LOCUS       DAMJXI010000001       148594 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.001, whole genome shotgun sequence.
ACCESSION   DAMJXI010000001 DAMJXI010000000
VERSION     DAMJXI010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 148594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 148594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..148594
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.001"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(141..335)
                     /locus_tag="PC465_000001"
     CDS             complement(141..335)
                     /locus_tag="PC465_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647342.1"
                     /translation="MFQVINFLCLFCVGFLVLDVMIYFCKDAMDIFEGTTNVNKVKSI
                     NVWVDRVRANSYSYENKIAK"
     gene            complement(644..2173)
                     /gene="lysS"
                     /locus_tag="PC465_000002"
     CDS             complement(644..2173)
                     /gene="lysS"
                     /locus_tag="PC465_000002"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HDF2647343.1"
                     /translation="MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRY
                     DRTHYSMDIKDNFDSLEGKTTKIAGRIMSKRIQGKAGFIDIQDQEGRIQSYVRLDAIG
                     EEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQE
                     LRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARP
                     FITNHNTLHIPMYLRIANELYLKRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIEL
                     YQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPWKRMSMEDCVKEYSG
                     VDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEV
                     SPLSKRNVEDPRRTDRFEAFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAF
                     EMDEDFLKALEVGLPPTGGLGIGIDRVIMLLTNSPSIRDVLLFPTMKPIDNNPNKEEE
                     N"
     gene            complement(2188..2667)
                     /gene="greA"
                     /locus_tag="PC465_000003"
     CDS             complement(2188..2667)
                     /gene="greA"
                     /locus_tag="PC465_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HDF2647344.1"
                     /translation="MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGD
                     LSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFD
                     EEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR"
     gene            complement(2776..3744)
                     /gene="dusB"
                     /locus_tag="PC465_000004"
     CDS             complement(2776..3744)
                     /gene="dusB"
                     /locus_tag="PC465_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HDF2647345.1"
                     /translation="MKIGNLELKNKVFLSPMAGVTDLPFRLICKEQGCGLLYTEMING
                     KALCYDDENTKKMLKIEEEEHPVAVQIFGSEPEFMGRAAEIMNDYSNEILDINMGCPA
                     PKVVKNGDGSALMKNPKLAEEVLRAVVKNSKKPVTLKIRKGWDDNSVNAVEIAKIAED
                     CGISALAIHGRTREQFYTGKADWDIIAEIKKNLSIPVIGNGDVFTIEDSINMLDKTGC
                     DAIMIGRGAQGNPWIFKRINHYMNTGEILPEPTLNEKISTAIKHLKLAVEEHGEYVAV
                     REMRKHIAWYLKGLRNSAKLRDEINKIEDYQEVVSKLEYYMEDSLT"
     gene            complement(3881..4651)
                     /locus_tag="PC465_000005"
     CDS             complement(3881..4651)
                     /locus_tag="PC465_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HDF2647346.1"
                     /translation="MLLVFDVGNTNMVLGIYKGDKLVNYWRIKTDREKTSDEYGILIS
                     NLFDYDNVNISDIDDVIISSVVPNVMHSLENFCIKYCKKQPLIVGPGIKTGLNIKYDN
                     PKQVGADRIVNAVAGIEKYGAPSILVDFGTATTFCAISEKGEYLGGTIAPGIKISSEA
                     LFQSASKLPRVELAKPGMTICKSTVSAMQSGIIYGYVGLVDKIISMMKKELNCDDVKV
                     IATGGLAKLIASETKSIDYVDGFLTLEGLRIIYEKNQE"
     gene            complement(4670..5260)
                     /locus_tag="PC465_000006"
     CDS             complement(4670..5260)
                     /locus_tag="PC465_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2647347.1"
                     /translation="MMNTSASVRKVNVRKMTIIGVLSAISIMLSMTPLGFIPVGPTKA
                     TIMHIPVIIGAIMEGPIVGAAIGFIFGISSLLNAITNPTVTSFVFINPLVSILPRVMI
                     GVLAYYVYQLIIKATNKVYISGLITGAIGSLLNTAGVLGMIYVLYADKYLHAMGKSGS
                     AGKVIMALAAANGVPEAIVGALVVAAVATVLKKSKK"
     gene            complement(5443..6411)
                     /locus_tag="PC465_000007"
     CDS             complement(5443..6411)
                     /locus_tag="PC465_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HDF2647348.1"
                     /translation="MYNNILDIEGLKVGQVEDRNGLTGCTVVICEEGATCGVDVRGSA
                     PGTRETDLLDPVNMVQKVHAVVLAGGSAYGLESTCGVSRYLEEKGIGFDVGVGKVPIV
                     VGAVLFDLGVGSFKCRPDLKMGYRACEVANTDILNQGNYGAGCGATVGKIRGQEYAMK
                     GGIGSYSIKLDNGLVVSALIAVNALGDVYENGKVIAGALNDKRTETIDTYKLMKQGES
                     KGGFSVDNTTIGIIATNAKLTKAGCKKISQMGHDGYAKSIFPIHTPHDGDTIFTISTG
                     EIEADITLVGSLAVEVVEKSIINAVKKADSVENIMAYKDIVKKREI"
     gene            complement(6404..7381)
                     /locus_tag="PC465_000008"
     CDS             complement(6404..7381)
                     /locus_tag="PC465_000008"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HDF2647349.1"
                     /translation="MRDKIIEIILNNKSEFISGEELSKQLGVSRAAIWKHMKALKEEG
                     YNIESVNKKGYRLAENPTDLLSPQNIYYKLDTEFIGKNIEHLDTIDSTNEHAKRIAIN
                     SVDGTVILSEHQDMGKGRLGRRWDSKPHEGIWMSIILKPNMEPFKAPFITLIAGASVT
                     KALNNLGANTLIKWPNDVILNGKKICGILTELSAEIERTNYVVLGIGINVKIMDFEQE
                     IADKATSLYKEGYMLSRVDIVRNVLTEFEKLYLDYTVNNSKEKTLKICRDYSAIIDKN
                     IYVLKGDNRELVKCLDINEEGNLLVQRSDGSIKEIISGEVSIRGEKGYV"
     gene            complement(7696..9666)
                     /gene="ftsH"
                     /locus_tag="PC465_000009"
     CDS             complement(7696..9666)
                     /gene="ftsH"
                     /locus_tag="PC465_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDF2647350.1"
                     /translation="MNKLLKGAGFYLLVFIIIVGIVQFSGKPTEKIKDLKFSEVYREL
                     TDENISRLYFVNQTSVEGTIKDTNTKFKSYVPTEVMGNKLADEVLDQAKAGKLTFGGE
                     AKPSTPWFVEMLPTLLLIFFMVIIWFVFMNQSQGGGGKVMSFGKSKAKVHKDDEKTRV
                     TFKDVAGLDEEKEDLQEVVDFLKNPKKYIELGARIPKGMLMVGPPGTGKTYLSRAVAG
                     EAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKSAPAIIFIDEIDAVGRKRGAGLG
                     GGHDEREQTLNQLLVEMDGFGVNQGIIIMAATNRPDILDPALLRPGRFDRQVVVGTPD
                     VKGREAIFKVHSRNKPLSDDVKMDVLARRTPGFTPADIENLMNEAAILTARKREKKIK
                     METIEEAITKVIAGVAKKSKVISEKERRLTAYHEGGHAVCAHVLEEVSPVHQVTIVPR
                     GRAGGFTMQLPVEDKFYATKNEMKENIVVLLGGRVAEELVLKDVSTGASNDLERVTAT
                     ARSMVTKYGMSSKLGPMSFDSDDEVFLGNSFSSKRNYSEEVAFEIDQETKRIVDGAYD
                     KTRSILQENMDRLEYVAQALLIYETLDAEQFVKAFNKELPLNEIENAVTEENSSKEVE
                     EQLTIKLEKDEEERNNVIDINKNLEDKSDKDK"
     gene            complement(9700..11088)
                     /gene="tilS"
                     /locus_tag="PC465_000010"
     CDS             complement(9700..11088)
                     /gene="tilS"
                     /locus_tag="PC465_000010"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HDF2647351.1"
                     /translation="MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKK
                     DFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIIFFVKSINVPKYCENEGLSLEE
                     GARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNC
                     IIRPILDVERNEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIE
                     SIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDNFVCLHDAIKVRVLRNS
                     IKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKDCIILTNEEIVNEE
                     IEFYYNVPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSR
                     RQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDSEGIICVGDYKISENYKIDEN
                     TKEVLKINFNKL"
     gene            complement(11271..11699)
                     /locus_tag="PC465_000011"
     CDS             complement(11271..11699)
                     /locus_tag="PC465_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HDF2647352.1"
                     /translation="MEEKSLSVKISINTRQYDEKGNMDTIEMTAFGKIFYKNDGIYVI
                     YKEKEENIEITNTIKILKNQVSIKKFGAINSTMLFKCGESSTTKYVTPQGTLLIDIDT
                     RELDINIQEGEHIKLKIDYNIKVQDLFLGRNKIDIYIGTK"
     gene            complement(11716..12522)
                     /locus_tag="PC465_000012"
     CDS             complement(11716..12522)
                     /locus_tag="PC465_000012"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HDF2647353.1"
                     /translation="MNNKPIGVFDSGLGGLTVLKEIMKILPNEDIIYFGDTARIPYGS
                     RSKETIIKYTFQAINFLKTKGVKAIVIACNTATARSLKEAQEKYDIPIIGVIEAGART
                     AVSSTKNKIVGIIGTEGTISSKAYNLEISKIDESIEIVNKACPLFVPIVEEGWANTEV
                     AKLTAKIYLQELKEKNIDSLVLGCTHYPILKRTIGEEVGEHIKLVNPAKETAKDLKKI
                     LEVQNIINNTEIHGTYQYYVSDIPEKFSDIAREFLKKKIDKIQKVEIQKY"
     gene            complement(12724..13209)
                     /locus_tag="PC465_000013"
     CDS             complement(12724..13209)
                     /locus_tag="PC465_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HDF2647354.1"
                     /translation="MATLLALTFIFMPIKEVFAYEPTENIKKVNKQEKNIAKKEVINL
                     SDNDLMLLSKLVAGEARGESYEGQVAVAAVVINRVLDPRFPDTIEEVIYQKNAFSVVL
                     DGSIKMAPTDSARKAAQEALYGTDPTNKAVYFWNPEIATCKWINRLNPYMRIGNHVFA
                     K"
     gene            complement(13260..13919)
                     /gene="spoIIR"
                     /locus_tag="PC465_000014"
     CDS             complement(13260..13919)
                     /gene="spoIIR"
                     /locus_tag="PC465_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HDF2647355.1"
                     /translation="MRKIKIRLGLLILSLISVISIMTIVINGEVKKVDNISKDYKDKL
                     IRFHVIANSNTDEDQELKLKVRDEVIKYLQPKLQNSKSIKESEAIIKKEYSSLEEISK
                     NIILKNGYNYSVKVGIQYSNFPTKQYSNIVLPAGEYKALKIIIGKGEGKNWWCVMFPP
                     LCFVDESNGVIDKSTDDKLKEVLTDKEYKLIKQDTPKKTSRVKIKFKVLEVVKDLEKK
                     F"
     gene            complement(14064..14744)
                     /locus_tag="PC465_000015"
     CDS             complement(14064..14744)
                     /locus_tag="PC465_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2647356.1"
                     /translation="MENLTKLNLDNYKPLRDVVFENLREAILEGKLKPGQRLMEVQLA
                     EQLGVSRTPVREAIRKLELEGLVVMLPRKGAYVANMSLKDIMDVLEVRASLEGLAAYL
                     AAERISDEDIKKLKDISEEFKKSTLESDVDALLKLDVEFHECIFKATNNKKLIQLINS
                     LWEQVYRFRVTYMSAYDTSHNIVEEHKYLLDAIIKGDSELSKKYATEHIEKAEQFMID
                     KAMISKDL"
     gene            complement(14728..15618)
                     /locus_tag="PC465_000016"
     CDS             complement(14728..15618)
                     /locus_tag="PC465_000016"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HDF2647357.1"
                     /translation="MDFIRLKSRAKINLSIDVLGKRQDGYHFVEMIMQTIDLYDIVKI
                     KELDEDEIKVKSTSLDIPLDEDNIVYKAAKILKNKFYIKKGVEIFIEKNIPVAAGMAG
                     GSSNAAAVLVGLNHLWELRLSEDELKEIGLNLGADVPFCISGRPALAQGIGEKLTNIK
                     GLPCDTNILICKPDLFVSTKEVYQGLDLNNIKKRPNNKYLIECLKSEDIKAVSESMVN
                     ILENVTIGKHKEISDIKQVMMKNNALGSMMSGSGPTVFGLFKNKEDALIGKKELLKKY
                     KQVYVVNSSQKGVEICGEFN"
     gene            complement(15736..17286)
                     /locus_tag="PC465_000017"
     CDS             complement(15736..17286)
                     /locus_tag="PC465_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 domain-containing protein"
                     /protein_id="HDF2647358.1"
                     /translation="MELIKDVIKVDNRIDFGKFQTFIEAEAVVPDKKLDVYEIVKTEG
                     YISLKKIEMADGKILCRGSFNYNVIYIADDKNTISNVDGKVDINEVIEKDNVIQDMEY
                     MLFSEVEHMDCTIMNERKIKVGALMNIRGSLFEKQRLDIVKDVAQVEGIQKHRKEICF
                     QDIVGIEKAESSIRDTITINTEEIQSIISLNPCVKVKESRVTDNKVIIGGVLEINPLA
                     CTYEGELVELDRVGIEFTQFVEVPGVSDGMTEEVLLSMSDFNHIFKQNSESNTGLLEI
                     DCMACCKVKVTDEVTREVLQDAYSPQKIIKFDHKPIQLNKTLRRSEETFMVREGIRND
                     NDDIQIKDIVSVCPTMSIENSYIEGNKSIIQGIIKVEILFVPVEGLKLVYKISEEIPF
                     EHDIEMDNLTDTASVFNTACIDKVEVDLNRDQIDLIIKIKRFTEALDKKAENFIIKGE
                     DQGVYDLSKAPSIIVYICKEGDTFWNIAKKYNTTENEIAELNDIKLDEPIKPGKCLIL
                     EKKVVLVD"
     gene            complement(17380..17646)
                     /locus_tag="PC465_000018"
     CDS             complement(17380..17646)
                     /locus_tag="PC465_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HDF2647359.1"
                     /translation="MATVQTLDKIRVSLERHIGKKILLKANKGRKQIITKEGILEKVY
                     PSVFVIKLDDESNGYPRVSYSYSDLLTSNVKLQVFRDQDKLQIS"
     gene            complement(17794..18654)
                     /gene="yabG"
                     /locus_tag="PC465_000019"
     CDS             complement(17794..18654)
                     /gene="yabG"
                     /locus_tag="PC465_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation peptidase YabG"
                     /protein_id="HDF2647360.1"
                     /translation="MKVGDIVARKSHNKDIVFKIVSFGVDENNEKIAILKGIAFRVIA
                     DAYIDDLELVKAPDIKDILIDKNVENLLYKSVRKAKERQKRMTRAVPKLQLNPNTYGM
                     PGKVLQIDGDKEYLKICLDVYAQLGIPAVGVAVSEQNQYKEVRALLEKYNPDILVITG
                     HDAMTIKRGDIEDMSNYRNSSNFVKTVKEARKWQPNLDNLVIFAGACQSNYEKIISAG
                     ANYASSPGRIMIHALDPVFIVEKIACSRIDVVVPIDEVIEQTITGVKGIGGSETRGKF
                     RWAMPKTILH"
     gene            complement(18738..19676)
                     /locus_tag="PC465_000020"
     CDS             complement(18738..19676)
                     /locus_tag="PC465_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HDF2647361.1"
                     /translation="MKFLDLHCDTIAKLMENVETSELKSNKYSVDIDRLKKGDSLAQT
                     FALFVDTEEVKHPFDYCMSMANKFHEEMKKNSDEIALATNYEEIMKNQSEGKLTALLS
                     IEEGAVLEGKLENLKKFYDLGVRMMTISWNHVNELSFPHNKVEYREKGLTDFGREVVH
                     KMNELGMLVDVSHISDGGFYEIAKISSKPIIATHSNSRAMMNHSRNLTDDMIKVLANK
                     GGVTGINFFHLFLSDKSESKLEDMVRHIKHIVNVGGIDVVSLGSDFDGIDSKVEIEDI
                     SQMGKLYEPLKKEGFSEDDIEKIYYKNALRVIKEVL"
     gene            complement(19786..19947)
                     /locus_tag="PC465_000021"
     CDS             complement(19786..19947)
                     /locus_tag="PC465_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647362.1"
                     /translation="MFILRFADDDDNLSVKDFTSLTDLKKYISENNIDKTWHQIEEVK
                     KVIPNLKEE"
     gene            complement(19957..20454)
                     /locus_tag="PC465_000022"
     CDS             complement(19957..20454)
                     /locus_tag="PC465_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HDF2647363.1"
                     /translation="MSLYTEWRNLSDNHESQEAEVKFWEEYLKVEAGIYNEILNNKMD
                     VVEGKVSELAEKFGTTNEFFMGFIDGISESLKEDIVLEEVEADKEVSIKIDWEKLYNN
                     MVTVEAHWLYNLQGWEDILPADQRKEIIKAYKKSKTIVKEAKIGRNDSCPCGSGKKYK
                     KCCGK"
     gene            complement(20569..21279)
                     /locus_tag="PC465_000023"
     CDS             complement(20569..21279)
                     /locus_tag="PC465_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0489 family protein"
                     /protein_id="HDF2647364.1"
                     /translation="MENYEYSGFYIEKPVGNNVFSYDKRENKSIYVPKLINGTLNDVR
                     LGNEVVFNEVDENKEIKAKGLENMVEYVLGNKKIYVFDNHNHAFYFWAKSLLKGEFTK
                     GCKLVHVDQHKDTREPENYDVDVNNLKDVFRYTNEVLNVGSFIKPALKYNIFSELIII
                     DSLYGFDLEVESEFVLDIDLDIFSSDMDYIPFELKFYKIKNLIKKAKVITIATSPYFI
                     NQEYAIKVLKELFNYDII"
     gene            complement(21455..21985)
                     /locus_tag="PC465_000024"
     CDS             complement(21455..21985)
                     /locus_tag="PC465_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647365.1"
                     /translation="MDIRALPIRITKEEAIEIAKSGKNSLFSKLILKNKYAHEVRLHY
                     IEFKIITLKIHKTKPIFKNRRYSNDINELKILVNGSTGSGSIVQDFPTYEIVKNVDCN
                     IVQYSDKDERRVKAKANKMAMRLTHRFMGGIPEIEIVKIESIFRPYWVVFFGKVELNR
                     RVSYLPIEADGFVIGM"
     gene            complement(22002..22232)
                     /locus_tag="PC465_000025"
     CDS             complement(22002..22232)
                     /locus_tag="PC465_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647366.1"
                     /translation="MSKLVSKVKKDLEIKWLGIDGFLVLLYFLITGFIFYGILTRNDI
                     IVGKIIPYGVMSVVIVIFFDYIYRVLKMTRKK"
     gene            complement(22247..23641)
                     /locus_tag="PC465_000026"
     CDS             complement(22247..23641)
                     /locus_tag="PC465_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HDF2647367.1"
                     /translation="MLTFWENGIIVIFAFILLGIGYYFSRNVKDMESYYLGNRSLPWS
                     LIVGTLVASWYGGVGTVGSVEYAAIYGISAWAVWSIAAHIGRMPLALWVGPRIHIRTN
                     ITVPDLLESFYGKHVAIIGAILMFIYCAQLGEITAMGTIGNVAWKIDKELIGLIMVGV
                     VVVLTVLGGLMGVAITDMVLFFCMVFGLTMVMPGQFEQIGGFQGLTEALKDAPQLMHP
                     TKGMSAMKALMLIVYSFGAYSDPTFYQRFSAADSPKVGRRALLTCFSLWICFDMVLTM
                     TGLIVRATYPEMAPAAGYITLVLDTLPQGIRVIFIIGILGSIISTLDSYYLAAGATLA
                     NDIYGRITKKELSQKQLVKFTRIGVCLAAVMGLSVAFRFENVYDACIFVGSIWMGSAF
                     VPIVGGLLGNGRRTSMGGILGMIVGGVTFGYFKIFPVQSFELEPLVIAIPFSFIAWMI
                     GNRIGENLNTQNNL"
     gene            complement(23767..25020)
                     /locus_tag="PC465_000027"
     CDS             complement(23767..25020)
                     /locus_tag="PC465_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2647368.1"
                     /translation="MESKNNVKRFLIIFILAFGTTAMYSLPYMKSSFYDPMQQALALS
                     HTQIGNLLSLYGLVGMVSYFIGGWFADRFSVRKLITFSLIASGILGFYFSTFPSYSMI
                     LLIFVLWGFTTILTFFSASVKVVRMQGSESEQGRIFGFYEGLSGVSGTLISFIGLYFF
                     GKFAEITVGFKYVVWLYSAASIICGILLFFLVEEKKDSGASDEGLSIKSLLKVVTMPK
                     AWLIGLIIFSTYLVFSSLTYLSPYLSEVYVMPMTLVSALSIIRTYVIKMGASPVAGVI
                     TDKVGSSIRVMFVGFILMTVSTAAYLVIPKSTGFIWIAVINMIILSVILFGFRGIYFA
                     SVSESNISLETTGAVVGFASFIGFSPDAFYYTIAGNWLDKYGQTGYTYIFILSVVCAV
                     IGIFATYALNKINKRENKGLNNKIA"
     gene            complement(25071..26225)
                     /locus_tag="PC465_000028"
     CDS             complement(25071..26225)
                     /locus_tag="PC465_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2647369.1"
                     /translation="MSNNINQNLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH
                     FEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGD
                     HIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPS
                     LDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLG
                     GAVAGSKELIDLVRWPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEF
                     LEEEENVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGINGLTRDQASRRLMN
                     SLELATIATSLGEEHTLVQMNGENLIRIAVGLESSNDIINDFKQAIEKLK"
     gene            complement(26785..27354)
                     /locus_tag="PC465_000029"
     CDS             complement(26785..27354)
                     /locus_tag="PC465_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2647370.1"
                     /translation="MIIIYGYCRVSTKNQTDNNSLYQQQQEILNKYNDAKIIKETYTG
                     TTTNRPKFEKIISSLKKGDLLVATKLDRLARSTSEGIQLIEGLFAKEVSVHILNIGLL
                     ENTSMGKFFLTTLLAVAELERNMIIERTQLGKEFAKKKKDFKDGRPKKYSNQQIQYAL
                     GLLNSKPYREVVKMTGISKSTLIRAKKSI"
     gene            27557..27784
                     /locus_tag="PC465_000030"
     CDS             27557..27784
                     /locus_tag="PC465_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2647371.1"
                     /translation="MNSLLKEAIDELKNIHCGEVFLLKELFKGYEWNRLEMNIRLKLG
                     KLFLYEVVTNPNLNVEVINKNSAYQQMYKKK"
     gene            complement(28003..28746)
                     /locus_tag="PC465_000031"
     CDS             complement(28003..28746)
                     /locus_tag="PC465_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDF2647372.1"
                     /translation="MENYQSTNTCTYNILYVQFNEDFERSKYFSYDVKYPVIYNIRNQ
                     STYVNPVILNNINNAVRMTVNNFKNGLQEEEREYNNAAPQNSLPKQSYWVSTSYAVTF
                     NKNYVLSMILNLMGFANNYGPKYNTLNNYNIDLTTGKELLLNDIFRDGVDYINIITDY
                     IKSQINENREMYYSNVELVIPEDQAFYLTDNGIIIYFGVDEIAPESFGIPKFELKFSD
                     FGNFINLRFYCISPDIYVQSRGRAKHFMG"
     gene            28914..29786
                     /locus_tag="PC465_000032"
     CDS             28914..29786
                     /locus_tag="PC465_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2647373.1"
                     /translation="MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESE
                     WALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAA
                     NWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
                     SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFV
                     DLCMGVLSDNPLFFLINSYTTGFSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDG
                     KILPCGIFGRWEKK"
     gene            29786..30451
                     /locus_tag="PC465_000033"
     CDS             29786..30451
                     /locus_tag="PC465_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDF2647374.1"
                     /translation="MIKVIYEDNHLLVVEKPVNILSQGDNTNDKDMVNLLKDYIKKKY
                     NKPGNVYIGLIHRLDRPVGGVMVFAKTSKAASRLSEQVRSKTFKKTYLAVVHGKIKSN
                     SDILKDFLYKNKKTNMVTVVKKSHKDAKEAELNYNVLDFKENLSLVQVNLKTGRSHQI
                     RVQFASRKHPLYGDQRYGKEINKIGQQISLWSNKIEICHPTTKEKMEFTCHPPDKYPW
                     NIF"
     gene            30472..31329
                     /locus_tag="PC465_000034"
     CDS             30472..31329
                     /locus_tag="PC465_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2647375.1"
                     /translation="MSKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYY
                     SIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKK
                     VLSTKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEKGLSSEETMELSRRQIANILE
                     DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICM
                     TYKGPYKENYTAFKKLVDYVEYKRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKK
                     REIDLRCLV"
     gene            complement(31485..34031)
                     /locus_tag="PC465_000035"
     CDS             complement(31485..34031)
                     /locus_tag="PC465_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2647376.1"
                     /translation="MNIFNKVALQGLKKNRTRTLVTIIGVVLSAAMITAVTTFGVSLM
                     NYMTNGAIIKYGDWHVQFLDVDSSFVQEQRVNDEVANTATFENIGYATLEGNRNPDKP
                     YLFIAGFSKEAFDTLPITLISGRLPENSREILVSSKVATDGGVKFAVGDTISLDVGKR
                     MSENEKLGQSDPYTAGSEVFVPQDKKTYTVVGICRKPVFEESSAPGYTLITKEDKQVK
                     TDSLSLFVTLKNPHQIRSYISSTKDHASIFNDNVLRFIGVSDNNLFNMFLYSVGGIVL
                     AIIMLGSIFLIYNSFNMSLNERTHQFGILSSVGATAKQLRNSVLFEGICIGAIGIPIG
                     VAIGIVSIGLVISVIAKNFANILYVNVPLTLTLSIPAIIVAAVVSMVTILISAYIPAR
                     KAANTPVMECIRQTNEVKIESKSVKTSKLTQRVYGLEGVLAMKNFKRNKKRYRSIVLS
                     LVLSIVLFISTSALVADLKQMSNQRSEVTDQDIIFSTQGMKDNEMLKLYDKLKTANGV
                     YEGLYQKLMTYSCVAKVSELTDDYLNYEGSHSMSEMLELPVDMQFLDDRTYLNIIKSL
                     GLPAEEYTGQNAKLIAVSMVTKDNNIIDIFNSSSMNVSLTPETNGKLEIPERQNVNIS
                     FVKVVPPDSPPGIRSSDVKKASFRVLAPYSAKDKFEIPGVSTGIESLSFQSKNPTQSV
                     AEMEQIIESEGVTNEYNLYNMYGMMDENRNYIFIANVFAYTFIIMISLISIANVFNTI
                     STNIKLRRRELAMLRSVGMSEHDFQKMMNFECAFYGMRALFFGLPIAVISSWLIHKVM
                     VTDDIDFVIPWFSIGISIFSVLFIVFITMLYTINKIKKENIIDALRDDMA"
     gene            complement(34031..34717)
                     /locus_tag="PC465_000036"
     CDS             complement(34031..34717)
                     /locus_tag="PC465_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2647377.1"
                     /translation="MAFLKIEDLCKVYGKNENKVTALDHVSLTIEKGEFTAIIGSSGS
                     GKSTLLHSIAGVDVPTSGKIYLEGQDVYGQSNEKLAIFRRRQVGLIYQFHNLIPTLNV
                     VENITLPILMDKRKVNQERLNDLLELLGLKERKTHLPNQLSGGQQQRVAIGRALMNAP
                     AVMLADEPTGSLDSKNGQEIIQLLKESHSKYHQTLIIVTHDENIALQADRIICISDGK
                     VVRDERKVNR"
     gene            complement(34800..35789)
                     /locus_tag="PC465_000037"
     CDS             complement(34800..35789)
                     /locus_tag="PC465_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2647378.1"
                     /translation="MFRNREFRKLAILFLLITILTVALGFAISIMTGILSIVSATTFG
                     IAFFVFTKNRYKSIAQISEQINLVLHNANHLYIAESDEGELSILQSEITKMTLRIREQ
                     NYALKKEKEHLADSLADIAHQLRTPLTSVTLILSLLENTSDEDERKELIRETEELLIR
                     MDWLITSLLKLSRLDAGIVVFQKEQIDVNNLISSALHQLLIPMELHNITLHIDIPKGV
                     RILGDLNWLSEAIQNIFKNCMESVGDNGKIDIICEDNFLFTQLTIHDNGAGFKKEDLP
                     CLFNRFYRGKNSSTAGYGIGLALCKTIIMRQGGTITAQNHPQGGAIFVIRFPK"
     gene            complement(35776..36462)
                     /locus_tag="PC465_000038"
     CDS             complement(35776..36462)
                     /locus_tag="PC465_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2647379.1"
                     /translation="MKRIFLVEDDKAIAKNLILLLNSEGFIVTHVSTRSEALVEIAKN
                     KFDLALIDISLPDGNGFTICTEIKEKQDIPVIFLTASGDESSVVTGLNMGADDYITKP
                     FRPRELIARIRTALRKSGRFGSTFEICGLYVDTATGVVKKNGNEVFLSALEYRLLLVF
                     ISNPKSIITRVRLLDELWDAAGEFVNDNTLTVYIKRLREKIEDDPSSPQIILTVRGTG
                     YRLGGSYVSK"
     gene            complement(36962..40168)
                     /gene="carB"
                     /locus_tag="PC465_000039"
     CDS             complement(36962..40168)
                     /gene="carB"
                     /locus_tag="PC465_000039"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HDF2647380.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQALKEEGIEV
                     VLVNSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKEKPDSLLAGMGGQTGLNLAVEL
                     HDAGILDKYNVKVIGTSIESIKKGEDRDLFREVMKEINQPVIVSDIVTNLEAGLEFAN
                     KIGYPVVVRPAYTLGGTGGGIADTEEELREILSHGLQLSPVGQVLLEKSIKGWKEIEY
                     EVMRDGNGNCITVCNMENVDPVGVHTGDSIVVAPSQTLSDEEYQLLRKASIDIINAIE
                     VQGGCNVQIALNPHSLEYAIIEINPRVSRSSALASKATGYPIAKVAAKIALGYTLDEI
                     ENAVTKKTYACFEPTLDYVVVKIPKWPFDKFRHANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHAPSEGRTLEELKARVVVPDDERLFDLAEMIRRGYKVEMISE
                     ITGVDKWFINKFKWIVEQEEKLKVLKIEDLDKEYLHELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIQPVYKMVDTCGGEFEALSPYYYSTYEQYDEVVVSDKRKVVVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMGIETIIVNNNPETVSTDFDTSDKLYFEPLTEEEVLNI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFRDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWTTNEGVEIAKELGYPVLVRPSYVLGGQGMEITYNEEKLIQYLDDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTAKSLRENGIEADIVNRIEEPRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKMRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDKLKVYNIAE"
     gene            complement(40361..41410)
                     /gene="carA"
                     /locus_tag="PC465_000040"
     CDS             complement(40361..41410)
                     /gene="carA"
                     /locus_tag="PC465_000040"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDF2647381.1"
                     /translation="MKARLILEDGTVFIGKAFGYLEESVGEVVFNTSMIGYGEVLTDP
                     SYYGQIVTMTYPLVGNYGINLSSAESEKVQVKGFIVREKSDSPSNFRCEIDIDQYLKQ
                     NKVIGLEGIDTRALTKILRNNGTMKGIITLEDSKLEDVKHKLDKFSNTEAVRTVTRKE
                     VEHIKGNGPKVAVMDFGVKRNILRSFIARGCDITIFPATTSPEDVLSINPDLIFLSNG
                     PGDPEDLEDVIENIKALIGKKPIVGICLGHQLLALALGGKTAKLKFGHRGGNHPVKDL
                     EEGKVFITSQNHGYYVSEVPEQMKVTHINLNDNTVEGMRHEKLDVYSVQYHPEACPGP
                     KDNDYIFDKFLELVK"
     gene            complement(41668..44874)
                     /gene="carB"
                     /locus_tag="PC465_000041"
     CDS             complement(41668..44874)
                     /gene="carB"
                     /locus_tag="PC465_000041"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HDF2647382.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQSLKEEGIEV
                     VLINSNPATIMTDKEVADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     YEKGILDKYGVKIIGTSVESIKKGEDRDIFREVMKEINQPVIVSDIVTDLQAGLDYAL
                     TIGYPVVVRPAYTLGGTGGGIADNEEELREILSHGLQLSPVGQVLIEKSIKGWKEIEY
                     EVIRDSKGNCIVVCNMENIDPVGVHTGDSIVVAPTQTLSNKECAMLKKASLDILNAVE
                     VQGGCNVQFALNPHSFEYAVIEINPRVSRSSALASKATGYPIAKVSSKIALGYTLDEI
                     ENAVTKKTYACFEPTIDYVVAKIPKWPFDKFKKANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHTPSEERSIEELKKRVVVPDDERLFDLAEMIRRGYKVEMIEQ
                     ITGIDKWFINKFKWIVEQEEKLKVMKIEDLTKDYLLELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIKPAYKMVDTCAGEIDAISPYYYSTYEQYDEVVVSDKKKVIVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIINNNPETVSTDFDTSDKLYFEPLTEEEVLSI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFDDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWSLNEGIEVANELGYPVLVRPSYVLGGQGMEITYNEEKLSQYLQDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTANSLRENGIEADIVNRVEESRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKIRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDELKVYNIAE"
     gene            complement(44927..45970)
                     /gene="carA"
                     /locus_tag="PC465_000042"
     CDS             complement(44927..45970)
                     /gene="carA"
                     /locus_tag="PC465_000042"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDF2647383.1"
                     /translation="MKGKLILEDGTVFEGKAFGYLKEAIGEVVFNTSMAGYGELLTDA
                     TYYGQIVTMTYPLIGNYGINLEDVESNKVQVKGLIVREKSDNPNNFRCEMDIDTYLKQ
                     NKVIGLEGIDTRALTKIIRNNGTKRGIITLENVSLQDVQSKLEEHCNKDSVKNVTRKE
                     IENIKGTGAKVVVIDFGIKNSVLESLKACNCDITIVPAMTTVEEILNINPDLILLSNG
                     PGNPEDINDIVENIKKLIGKKPLTGIGLGHQILALALGGKTSKLVFGHRGGNHPVKCL
                     ETGKVFITSQNHGYNVSEMPENTEVTHINLNDNTIEGMRHKELPIYSVQYIPEYTTKE
                     DLDCIFNKFLALI"
     gene            complement(45996..46712)
                     /gene="pyrF"
                     /locus_tag="PC465_000043"
     CDS             complement(45996..46712)
                     /gene="pyrF"
                     /locus_tag="PC465_000043"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HDF2647384.1"
                     /translation="MINGKEKLIVAIDTDEFDKAKELIDRLEDSVDIFKVGLEQYVAT
                     KGKTIDYLKEKGKKIFLDLKFHDIPNTMKSAVRAAVRDNVWLMTIHVSDMEGMRQCAL
                     IAREEAERLNIEKPLVVGVTVLTSLSNQDLQDIGCNMTTEELAIKRAKLAKESGIDGV
                     VCSAQEVDKIVEACGTDFITVCPGIRPKSAEVGDQKRVVTPSDAIKKGAHYLVVGRPI
                     TKAENPRESAINIVREIENA"
     gene            complement(47088..47723)
                     /locus_tag="PC465_000044"
     CDS             complement(47088..47723)
                     /locus_tag="PC465_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1847 domain-containing protein"
                     /protein_id="HDF2647385.1"
                     /translation="MYKCGKCNLRGCSNGNMDKLMKICPTREIELQQKAKQLYEEEEN
                     RKIAYNAGLVEAEGYCQYTRLKEIIEFAKKCGYKKIGIAFCIGLKREMQTVQKIFEHH
                     GFEVFSVICKNGAMPKSTIGLEASQTISKCSDEVMCNPIGQALFLNEAKVDLNVILGL
                     CVGHDTLAMKYMEAPITTLVVKDRVTGHNPVAAIYNAESYFEKKLFDKDEE"
     gene            complement(47747..48661)
                     /locus_tag="PC465_000045"
     CDS             complement(47747..48661)
                     /locus_tag="PC465_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647386.1"
                     /translation="MELYEAIFYRKSVRNFSSKKIKKPLMEEIKRSCKNLEYLNEDLN
                     IKAHVVDRGHIIHFLMGKECKVKAPHYIVVTSDKGEDYLQNIGFATEGVVLRLTTLGI
                     ATCWLEGNLKREDILEFVDIGNKNFEEDEEDDLDYLAGIKTEEDDENKIENPYIIIAF
                     GYPAKNEELFRTRYARPDRKPVKDMINKINRNRKWKDILELTRRAPSVKNSQPWYFHK
                     DERGLHLFEKRPKKHCEDMNKVSLGVALRHFDIACIKNKIDVSYEKLPIRNKIGKSYF
                     ITVVEHVKPEEETQEENVTLEKEESQDE"
     gene            49262..50491
                     /locus_tag="PC465_000046"
     CDS             49262..50491
                     /locus_tag="PC465_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDF2647387.1"
                     /translation="MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALK
                     EAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYA
                     QNPDLLKDVDPERVANFQKASGKALKEWRSYTLTDKCKWSIVSVPTKDWAKKVFPNLS
                     EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDL
                     TLDLPKGHVWLSGASKDPNGISFNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNII
                     DNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVPYNSPISNTDIIFYN
                     TLYDENASCHFAIGSAYKTCLEGGNNLKDEELDEHGVNDSLTHVDFMIGSADMDIIGE
                     TYDGKQIQIFKNGNWAF"
     gene            complement(50696..53077)
                     /locus_tag="PC465_000047"
     CDS             complement(50696..53077)
                     /locus_tag="PC465_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="HDF2647388.1"
                     /translation="MEIRQYLKNNILIFDGAMGTMLQQKGLKLGENPEVFGLQNPDKL
                     IEIHTAYLEAGSNVILTNTFGCNELKLDSKYTVEEVIDNAVLVARKAIENVDNTKPRY
                     VALDIGPIGEMLEPMGTLSFDKAYEIFKRQVLQGVKSGVDVIVIETMMDLYEAKVAVL
                     AAKENSDLPIFCTMTFDEGGRSFTGCMPECMVATIEGLGVDAIGVNCSLGPKQLLPIV
                     EKIASRATVPVMVQANAGLPNIVDGEAIYDVDAKEFFEGVKKFVEVGATIIGGCCGTN
                     PSFIKEISENINSVTKGCIEKIDKCVVCSPSKFVEVQSPTVVGERLNPTGRKSLQEAL
                     KNENVDYAINLGLEQVNAGAQILGVNVGLPEIDEKKLMPKLIREIQAVVDTPLQVDSS
                     NVEALEQGLRYYNGRTIVNSVNGKEESLESILPIVKKYGSCVVGLTLDEKGIPKKAEE
                     RFEIAKRIVNRAVSYGIKPKDIFIDCLSLTVSAQQEEAIETIKAITMVKTLGVKTILG
                     VSNISFGLPNRKALNASFLTLALGAGLDLAIINPNEYSMMEAINSFKILNNTDKGCIN
                     YINQYSNINNSKKSDSSTKIDKDLPLDILVERGLKDEAKNVTLNLLKEKDENYILDEI
                     LIPALDKVGKRYDSGDIFLPQLIQSAETVKVSLNTIKETLLSKSSNNVSKGKIIVATV
                     KGDIHDIGKNIVKIMLENYGYEVIDLGKDVPIEEVVEVAKNRNIKLVGLSALMTTTVQ
                     SMKDTIQALRDNEINAKVFVGGAVLTEEYAEEMGADYYSKDAKSAVEIAKLNF"
     gene            complement(53049..53774)
                     /locus_tag="PC465_000048"
     CDS             complement(53049..53774)
                     /locus_tag="PC465_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vitamin B12 dependent methionine synthase,
                     activation domain protein"
                     /protein_id="HDF2647389.1"
                     /translation="MENNLIGREDISINQSEVLRYLQYRGQEIDKDLKYTIDECVAIT
                     KNKINPRYLSRIYPIKINKDNVVELEGTNLTLESKDVYELLKECNECVIMAATIGIDI
                     EKEIRRHSYSNLTKGLIIDSCGTTAIEEVCDIVQNNLEKVFLKQDKFITMRYSPGYGD
                     LPIEKNIDILNVLNAQKQIGLTITSNGIMIPRKSVVAIIGISNTRINKSKKEKSCENC
                     KNYRNCTYRKGANSCGNKTISEK"
     gene            complement(53764..54219)
                     /locus_tag="PC465_000049"
     CDS             complement(53764..54219)
                     /locus_tag="PC465_000049"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HDF2647390.1"
                     /translation="MEKVESFKLDHTKVKAPFVRKCSVLDGVKGDKVTKFDLRFLQPN
                     VESFGTAAMHGLEHLLATYLRDTLDGVIDLSPMGCRTGFYLILWGDVDAKTVKIGLEE
                     ALKKVLESDKMPAATAIECGNYRDLSLFGAKEYAKDVLDKGFSLNIYGE"
     gene            complement(54501..55682)
                     /locus_tag="PC465_000050"
     CDS             complement(54501..55682)
                     /locus_tag="PC465_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HDF2647391.1"
                     /translation="MKNKSLLNHMFRPILDLIISCALTSMLILTSMYIIKSLYVNSDM
                     SVVNQLVYQARDFRSLIGYDLFYPFLFTITSLAIYSIISYKRNKQIVDFIRKTNRKNQ
                     KLEIIKSAVNLMDEGNLEKSIDIEYDLDILKDKEKDDIDELAHKINNIVHQLRNITIE
                     ERQAQQTKTDLITNVSHDLRTPLTSIMGYLGVIEEGKYKDEVQMMYYVDIAYEKSKNL
                     KVLINDLFELTKMQNNTIKLNKIEINLVELLSQVVSQFEIYFKQEFMVSRINFNEEKL
                     IVKADPNKLVRAFENLITNAVKYGKDGHYVDIVTEKKEDMAVVKVINYGEPIPVLDLP
                     NIFDRFYRVEKSRNRNVGGSGLGLAITKNIVNLHDGEITVSSDKYQTMFEVQLPIIQS
                     A"
     gene            complement(55672..56364)
                     /locus_tag="PC465_000051"
     CDS             complement(55672..56364)
                     /locus_tag="PC465_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2647392.1"
                     /translation="MNNTVLVVDDEKEIRDLIEIYLLNSGYNVIKAEDGKEALDILKK
                     ENIHLMILDIMMPKMDGIEVCRKVRESLNIPILMLSAKSEDMDKIQGIMTGADDYLTK
                     PFNPLELTVRVKSLIRRAYYFSGANNEDKDVIKVGVVIIDKEKHSVTVAGNEIILTSR
                     EFDILYLLANNKGRVYSTEEIFEKVWKEKYYQSNNTVMVHMSRIRDKIEKYTDGEKII
                     HTVWGVGYKIEK"
     gene            complement(56498..57214)
                     /locus_tag="PC465_000052"
     CDS             complement(56498..57214)
                     /locus_tag="PC465_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2647393.1"
                     /translation="MKKFKLIGAIILVVFISVFISKDRLLKKDNDPIVAAQHDSEQDV
                     EANSQNKNHSNSISNILLVNKTNGISKNYTPENITKVNIPFVEEATEEEKQMAGEPAK
                     AVEDLVKQANSEGIQFLGSSAYRSYDTQLDTYTRRVKSQGREKADAYVAKPGYSEHQT
                     GLCIDLTNPERWFVGSTKEAKWLAENAHKFGFIIRYPEGKEDITGTAYEPWHIRYVGK
                     DAAEEIYSKGLTLEEYLQNK"
     gene            57339..58073
                     /locus_tag="PC465_000053"
     CDS             57339..58073
                     /locus_tag="PC465_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HDF2647394.1"
                     /translation="MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILK
                     SYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRQEKNP
                     CALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
                     QDLTVIRPMVYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDF
                     KRNVFGALNNSEKLFIWDKEKIKNFK"
     gene            complement(58358..59209)
                     /locus_tag="PC465_000054"
     CDS             complement(58358..59209)
                     /locus_tag="PC465_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2647395.1"
                     /translation="MNSKIKYFLKFFILIFILIFIYSVAIEPSLLIVKKYNISENGAL
                     IKNDTIESKSESVKVVQISDTQIGSFYSTKNLKKVANKINTLNPDIIVFTGDLIDYSN
                     KNPSVDEITTILSSMNARLGKFSVFGNHDYMYKLPRYYRQIMKNSNFNLLVNENKKIK
                     LKDDKYINILGVDEILNGNPNIKYLESQIDNKSFNLLLAHEPDLVDMLSKDTMNLVLS
                     GHSHGGQIRLPIKGALVTPPYGRKYTKGFYDINGNHLYVSSGLGSTKLPFRFFNIPEI
                     IEFNIII"
     gene            complement(59235..60173)
                     /locus_tag="PC465_000055"
     CDS             complement(59235..60173)
                     /locus_tag="PC465_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDF2647396.1"
                     /translation="MKSILIMGGSDFIGSALAKRLIKCGYQIDILTNGKKEIDYNGFK
                     EHLICDRKVRKDMENIITGRKYDYIYDMTAYTKEDVSNLIDFISMDNLKKYIVLSAGA
                     VYKDSGRNIKEENEKGENENWGKYGLNKKEAEDFIINSPIPYIIIRPTYIYGENNNLY
                     REYYFFEKIEKNEKIPVPKGKQVSNQFIYIGDLVKVLESIMKNPHVREAYNVTNPQLI
                     SWDDLIYTCGEIIGKEPIIKYVDMEKVEFRERTYFPFRNIDFNLDINKLIEHGLYIPN
                     VLLKEGLTATYKWFSANKPKMHDRKMNKVESVMQIV"
     gene            complement(60276..60926)
                     /locus_tag="PC465_000056"
     CDS             complement(60276..60926)
                     /locus_tag="PC465_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDF2647397.1"
                     /translation="MKKNYEIILFDLDGTLTDPKEGITKSIQYSLNSFGIEEDLDNLE
                     QFIGPPLHDTFKEYYKFEDKKAKEAVEKYREYFADKGIFENKIYENMKEILEMLYKNG
                     KILLVATSKPTVFAETILRYFDIDRYFKYIAGSNLDGTRVNKNEVIQYVLDLCNVKDK
                     DKVIMVGDRKYDIIGAKKIGIDSIGVLYGYGSFEEISESEPTYIVENVESIKDILL"
     gene            complement(61075..61263)
                     /locus_tag="PC465_000057"
     CDS             complement(61075..61263)
                     /locus_tag="PC465_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HDF2647398.1"
                     /translation="MKAFVDKDVCVACGACIGTCPDVFSMSDEGHSVAIEGEIPADLQ
                     DLCKEAEEGCPVSAITVK"
     gene            complement(61370..62554)
                     /locus_tag="PC465_000058"
     CDS             complement(61370..62554)
                     /locus_tag="PC465_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2647399.1"
                     /translation="MKNLLIRNGTIISPTDGIKFEKRDILVLHGKIYAIGLNLKEKIR
                     KEKLLTNKEFEIINADNMYISPGFIDVHTHCYKRKLPTGMDSDSIGIEKGSTVIFDAG
                     TAGPSNYYDFKKKYMDECKTEVYSFLNVTNEGLNILNESTSLDVINFDKVESIVEKNI
                     EKIKGIKVKASKFQSNESGIDIIKKSKQVAKKLNLPLVVYIGEYPSYIDEVMNILGKG
                     DVVTPVYGNSTNGILKESGTLRKSVINAKNRGVLFDVCHGVDQFDFKVFKKAIKQGLE
                     PDLISTDMHIKNMKDVNYSLLNVINKIMELGISLEKCIEKVTEYPTKIFDLHGNKGRI
                     KIGGEGDFTIFTMEECNDIIKDYNNNELVLNKKLRLQYTVKSWMKSSEVYRHGYENTI
                     IN"
     gene            complement(62696..63613)
                     /locus_tag="PC465_000059"
     CDS             complement(62696..63613)
                     /locus_tag="PC465_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HDF2647400.1"
                     /translation="MNKIDLNLLEKVAELRGTPLGAYNIRKNGQGVERHSTENVTIIP
                     KTDKPGIDIIVKPNTKGENVHIPVIVTEAGVQDMVYNDFEIGENADVVIIAGCGIHNC
                     GCDDSEHNGIHRFFLRKGARLKYVEKHYGEGDGEGKRILNPVTIVNMDEDSYCEMETI
                     QIKGVDSTKREMDANLGKGAKIVVFEKLLTHGNQVAESNMKVILEGENSSAQVVSRTV
                     GQDNSKQKFNPCVIGDSLCSAHVQCDSIIMGNSQISAIPEIAANHPDALLVHEAAIGK
                     IAGDQILKMMTLGLTEEEAEQQILNCFLK"
     gene            complement(63635..64363)
                     /locus_tag="PC465_000060"
     CDS             complement(63635..64363)
                     /locus_tag="PC465_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2647401.1"
                     /translation="MLEIKNLSFNVESNNEELGIINDVSLSFERGKLIVITGPNGGGK
                     STIAKLIMGIEKATSGQIILDGEDITNLSITERAKKGIGYAFQQPPRIKGMTVENLLT
                     LAHGKPLSTDVCCQYLTDVGLCSKDYLNREVDNSLSGGEMKRIEIATLFARDLKVSIF
                     DEPEAGIDLWSFGKLNESFKKIHEESNQTIIIISHQERILELADEIIVLQDGSVKSHG
                     TKEAILPEIMCQVNSSCELMKDMN"
     gene            complement(64559..64759)
                     /locus_tag="PC465_000061"
     CDS             complement(64559..64759)
                     /locus_tag="PC465_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647402.1"
                     /translation="MFKKMAVLKDIATKIGRKKAYELLEMVEGNDAFVAEVKIKKNGI
                     ESKKEEIMLKDNQKIILEYIEG"
     gene            complement(64884..65264)
                     /locus_tag="PC465_000062"
     CDS             complement(64884..65264)
                     /locus_tag="PC465_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2647403.1"
                     /translation="MINKIGKITLYVNNQEDAKLFWTEKLNFVVTYEKEMGPNMKWVE
                     VAPSKNEFTTFVLYDKNLMMKQNKEINVSHPSIILSTRDINGTYEQMANNEVEVGELM
                     EMPYGRMFSFKDQDGNDYLVREDK"
     gene            complement(65537..66895)
                     /locus_tag="PC465_000063"
     CDS             complement(65537..66895)
                     /locus_tag="PC465_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2647404.1"
                     /translation="MFIRKNVIKLAIPIMIEQTFVMLLGVFNTMMAGHIGEEAVSAVG
                     MVDSINNIFISVFAALSVGATVVVAQQIGKKDGEKVNETIKQALVSGVILSFTITILM
                     WVFRTGVINLFYGSAEELVKSNAKLYIEFTLFTYPFIATQQIANGILRGCGDLKKPMY
                     VTMFMNIVNVTLGYILIYGIDLNPLGINLQTPSYGITGAAISIAIARIIGCIVIIRVL
                     FKGNEFISMGKIFPFKIDVETQKSIFNIGIPAGVEQLLFNAGKLIVQVFIVTMGTSAI
                     ASNAIGMSIASIINVIGNALALSATTLVGQYIGRGDIKGAKSTLLYLTKFATICLFIV
                     GAIFIPIAPWISSMYTQNASVIDISTQLIRSDCLAMVIWPISFVLSAGLKGAGDTRYT
                     MMTAVIGMWIFRIFTGYVLGVVLEFGVLGIWIGMYTDWLVRGTLYCLRLRGTKWLKHK
                     VA"
     gene            67343..67795
                     /locus_tag="PC465_000064"
     CDS             67343..67795
                     /locus_tag="PC465_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staygreen family protein"
                     /protein_id="HDF2647405.1"
                     /translation="MVNLNANNLNVNMVYPISSTAPIRFRRYTVSYLENMENIYLTIA
                     TYFDTLGLGTMNIDKVYGQWAWFTDNIYDLNLFVFVGNYPYQIAKNRYDTFVDILPVA
                     ITSIVNGDRVFLISNPCLLNSKITVRFISSHPTLNRTVDYGNIRDFIF"
     gene            complement(67952..68569)
                     /locus_tag="PC465_000065"
     CDS             complement(67952..68569)
                     /locus_tag="PC465_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HDF2647406.1"
                     /translation="MEIFAIGHSNYPYDKLINMIKKYDINCVVDIRETPYSKYNIQYN
                     KEAFNESLRNSGFLYIYMGKEFGAKRTNKDVYTQEGYADFEKVAKEDIFLNGIERLKK
                     GCQMGYRIVLLGAMQEPIRCHRSILVGKVLNKEGFDVKYIMHEGNLAYQEDIEESLLD
                     KYFSDRKQLSIDNLLGSALTREEMIQEGYKLANKEIGYRTEKLGK"
     gene            complement(68992..69804)
                     /locus_tag="PC465_000066"
     CDS             complement(68992..69804)
                     /locus_tag="PC465_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2647407.1"
                     /translation="MFSIGMFSKINKITTKTLRYYEDIGLLKPEYVDEFTKYRYYTTE
                     QLPKLHQIITLKQMGLSLAEIKKAVENPEEVENILMNKEKEMLDVIKSEEYKIIKLRN
                     YLMNLKGEVNMNDVIIKSLPKVKVASMRKVLKGYDELFNLFPNVMAEEMMKTGCTCAV
                     PDYCFNIYHDGEYRETDMDVEMCQAINDLKEDTDILKFKELDAVENAVCILHNGPYST
                     LGKTYADAFKWIEDNKYKVVGNPRESYIDGIWNKESEEDWLTEVQIPVKRML"
     gene            complement(69880..71298)
                     /locus_tag="PC465_000067"
     CDS             complement(69880..71298)
                     /locus_tag="PC465_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HDF2647408.1"
                     /translation="MTELMIISGLVLLICITSSKVLYKFGVPILLIFILLGMLFGSDG
                     MVGIYFDNYELTKQLCSIGLIFIMFFGGFGTNWNMAKPVAIPSILMSSLGVIITAGVT
                     GMFCHMVIGTSLLEGLLIGAIAASTDAASVFAVLRSQKLNLKGSLASLLEVESGSNDP
                     IAYMLTLILLTLMNNSGVELIAPMVIKQIAFGLAIGFILAKLSVYILRHSNFEIEGFY
                     TIFITAIAILSYAFSEYLGGNGYLSVYISGIIIGNSRIPLKKSLVHFFDGISWIMQIM
                     LFFMLGLLSFPSKLPNVFGIAMAISIFMIVIARPLATFIVLAKFKFSNKEKLFISWVG
                     LRGAASVVFAIYAVTQGVAIENDIFHIIFFIALLSVGIQGSLIPTVARKLDLVDDNTP
                     VLKTFNDYDGEISSKLIEVNVDEGNKWANKSIIDSNIPDDILIVMIKRKEQVLIPKGS
                     TIIKTGDILVLSGDRIEELIQL"
     gene            complement(71782..72699)
                     /locus_tag="PC465_000068"
     CDS             complement(71782..72699)
                     /locus_tag="PC465_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HDF2647409.1"
                     /translation="MVNMNIIEIRSDKIYKKIMDAPINKKEDIYRYELMKPFEFKWKC
                     MNVPIVARQKGGYDVIIASEMLGVLSPKDIDEKQKKNINVLSADKIWATCKETIENSI
                     NAFIKEGYDLNIKDYKYSILLANPNSPYTILSDGYWGDGGIPGYIFLSLVPNEYTINR
                     LPVLIAHECNHNIRFQFIEWNNNVTLEEMMINEGLAENFATWMFGEEMLGPWVSRTDI
                     ETLNTYIKPIIKSALKETGFQNITSYLYGDDIAKMQGYFPVGLPYCAGYACGYYMIKY
                     YLEKTNKSIIEATLLPYSEIIEAVKEFWE"
     gene            72961..73338
                     /locus_tag="PC465_000069"
     CDS             72961..73338
                     /locus_tag="PC465_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2647410.1"
                     /translation="MLTPYLIFNGTCEKAFNFYAEAFGGGKTIFARLDSNPNNPIMHA
                     SVTFTKYEGCIMGADTDKPVVISGMAICVVLPSREAIEEISVKLAEGGTLVQEFLPHP
                     PPHQNDGAAEVLDRYGYTWYLST"
     gene            complement(73494..73943)
                     /locus_tag="PC465_000070"
     CDS             complement(73494..73943)
                     /locus_tag="PC465_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2647411.1"
                     /translation="MKSGIILEMKQINSTEYDEMLQVWESSVRATHDFLTEKDIESLI
                     PLVEIGLKEVENIVCIKDNDIIKGFIGIDKDKIEMLFIEDKYRGNGIGKKLIKYAIDK
                     YNVKYVDVNEQNKKAVGFYIHLGFKVFDRSEIDGQGNPFPILHMKLI"
     gene            complement(74110..74514)
                     /locus_tag="PC465_000071"
     CDS             complement(74110..74514)
                     /locus_tag="PC465_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmaF family protein"
                     /protein_id="HDF2647412.1"
                     /translation="MSYQNYKCERDYVYDDYKYNKCNKCYNDYEEMTHVHEYSESVKL
                     AEECEDRHNHRAAGVTGEAIPINGGTNHVHKINDNVDFLDHFHKICVTTGPAIRIPGT
                     DKHIHLICGETTVNDGHCHKFLFTTQIEAPLV"
     gene            complement(74627..75493)
                     /locus_tag="PC465_000072"
     CDS             complement(74627..75493)
                     /locus_tag="PC465_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDF2647413.1"
                     /translation="MIDIHKNIYDNKLFEELKIDCKKCFGLCCVALYFSASDGFPIDK
                     ESGKPCINLQPDFKCSVHNSLMKRGFKGCTAYDCFGSGQKVAQVTYKGIDWMQSSELT
                     NQMSEVFLIMRQLHEMLWYLKEASVLNISDTIKSKIDLIIEETEKITNMGPEQIINLD
                     IISHRTKVNLLLSQASESVMGKVKSFIKTSTLKNMKKLSKNIDLIGADLRKINLIGAD
                     LRGRFLIAANLRNTDLSGANLIGADLRDCDIRGANLENSIFLTQLQVNTAKGDSSTKL
                     PASLIRPKYWEK"
     gene            complement(76063..76407)
                     /locus_tag="PC465_000073"
     CDS             complement(76063..76407)
                     /locus_tag="PC465_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HDF2647414.1"
                     /translation="MENLPNCPKCNSEYTYEDGTLLVCPECSHEWALGLGAEEDSNII
                     KDVNGNVLNDGDSVTVIRDLKVKGSSSSIKIGTKVKNIRLIHDSSDGHDIECKIDGFG
                     AMKLKSSVVKKA"
     gene            complement(76596..77213)
                     /locus_tag="PC465_000074"
     CDS             complement(76596..77213)
                     /locus_tag="PC465_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2647415.1"
                     /translation="MISLINISKKFKDKSIIDKFNLEISKGEFVAITGNSGSGKTTLL
                     NIMGLLEKPNSGDIIINNIKNPNSKQIRILQRDFYGYLFQNYALIENENVENNLKIAL
                     KYQKNINHNEKINYALESVGLRKYNKKKIYELSGGEQQRVALARVILKECEVIFADEP
                     TGNLDKKNRDIVFDILKSLNKNGKTIVFVTHDLELSEQADRVIKL"
     gene            complement(77218..79380)
                     /locus_tag="PC465_000075"
     CDS             complement(77218..79380)
                     /locus_tag="PC465_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HDF2647416.1"
                     /translation="MKKIIYVLFTIELLIVSLLGLNIVKDNEINNILYNDTTSISVMF
                     KDYKKLNKNYSKWIKDIADENNVTISKYVFNNNEKLSIYTTDTSLNNNIKLKSGKFPN
                     TNSNEFISNINTNNSNQVGKFSTMSKDISILIRDFGKISEVGESGILYISTQNEDTIN
                     KILRELNVDRSIFVARLHDRYVNSNLYLNPSIIRDLILIILCFLATIIHYSISVSREA
                     SILRLNGYSKLDIIARVIKNILRIMILSSVTALLIYIIYILKLNIGVRACLYFAMFSI
                     ICILINILISILIVGFNSRSSKYVLSLNGKKSYGFVNIMHFTLKIVFVSFLILSINNC
                     ILNYNMLQTQLGNLSEWDKAKNVYNLTLKDTGEQSLGKEEVIKNAKIKGFYKNLVEEK
                     DAFLIDSTNFEKLEDGSYMYEINSKGKNPEVSQYGKNIKINKNYLKVNPIYSNGKEIF
                     NLIDYGDKTINLLVPKKLQVHENEIKKEFRELFYFEKIEVENMYNKELNRELNKTKKS
                     DLNVNIIYVDNNQSYFTYNSLVMDDNRNLIDDPIAIVDIDNIDDSFYLSYISRCVYFN
                     SKKLDALADISNIIEAQGVEAHIQSLHAVYNEYGLEINKLEKYLNSEIFTIIIIAISN
                     LMITYNIVASYYERNKYKLYIKKIFGYSTTARSMLLIVSLILTNIIPIGIISTRVDLS
                     NNIILFGLLILVIEVIVSIALDKIISNSSFNKIIKGEH"
     gene            complement(79722..82229)
                     /locus_tag="PC465_000076"
     CDS             complement(79722..82229)
                     /locus_tag="PC465_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2647417.1"
                     /translation="MKEDIRLHRMCKKEQATKNEVISEDILKSMSIGVSKHFLDDSFT
                     IIWGNTSFYQLLGYTEEEFLVKFSSLKDYYEQNLYHFESMKNHFLEAYHHGEKSIEYQ
                     ICISANNGDPVWVIMTGILIESQDNEKSMVYILYSKINELKIKQEELSDMEKESTENF
                     KWMMSEYAGNVYISDMDTYELLYLNKHSCNTLQASANELIGRKCYEVIQGRTSPCPFC
                     TNSYLKKDDIYEWEFYNKKLKRTFIIKDRMLNWQGRRVRIELSYDMYSAEYKLAKKDQ
                     ERESILKTIPAGMVRLDARDYLTILWCNDIFLNMIEYTKEQFAEELNNQCGYLFSEDY
                     KRSKKLAQDLKESGDNVVFEAKIYTRSREERIWTVTLCYISGEDSWDGIPSFYSIGID
                     ITKERKQIEKLQHISEKDALTGIYNRAETERQIKKYFEKNLNVMGALFMIDTDNFKQI
                     NDTEGHMIGDIVLTEMASGMKKIMRDSDVVGRIGGDEFTIFMKNISSVKDAEKKAEEL
                     LYMFRHLFQKEKSFLKVTCSIGIAIYPKDGTTFKEIYARADKALYQAKNMGKNNYVIY
                     NQDYFKELEEFDCSSLGTVIDSEKQYAEYPDNLTRYIFRMLYQTDDIDQAINMILEVV
                     GKQFDVSRVYIFENTEDGRYTSNTYEWCNEGISSQMAYLQNSNYQDYEDYEKLFEDEL
                     VFYCRDIHTLSPKLEELFSSQGIHSTLQCAYKEDRVFSGFVGFDECTGLRLWSQEEIS
                     TLSLISQIISMFLQRKKNNKLNQQIQQYQNILDNIDQCICVINKENNFLLYVNKKFKN
                     TYSKFQIGQPYYLDSIDIHKISIIWNKKEAYLCTSTI"
     gene            complement(82707..83339)
                     /locus_tag="PC465_000077"
     CDS             complement(82707..83339)
                     /locus_tag="PC465_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketohydroxyglutarate aldolase"
                     /protein_id="HDF2647418.1"
                     /translation="MKKMNITKRMSECGALAIVREENLNRACEIAEGCIKGGITVIEM
                     SYTLNNAGEIIQGLNKKYGETLCVGAGTVLDSETARHAILHGAQFIIAPNYNEGVAKI
                     CNRYQIPYAPGCTSLTEAVDALSLGATFIKAFPISDFYGPKLVKVFKTPIPDMPVLAS
                     GGINIENLHIWLENGVDVCGFGGLLTKGSVEDIAKNAKKIREIIKNIRKI"
     gene            complement(83445..84350)
                     /gene="dapA"
                     /locus_tag="PC465_000078"
     CDS             complement(83445..84350)
                     /gene="dapA"
                     /locus_tag="PC465_000078"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDF2647419.1"
                     /translation="MKYKGIICAMITPFDENQNINSQATCQLIDYLIEKGIYGLFILG
                     TNGECHVLTDDEKVEFAKIVINHTNNRVPVFVGTGGNSTREVVDLSKRMEAIGASALS
                     IITPYFVTPTQQELILHYKTIANSVNLPIIMYNMPGKTGINIEPESVRELSKIKNIVG
                     IKDSSGKLDNMKAYIEATKNENFSVFSGSDSLILDSLKAGSQGAVAATTNFLTEIGIS
                     IYENFMKGDLEEAQKAQSSIEELRRILKLGTIPSVMKKTIVLNGINVGTARLPVTEPT
                     GEVLEEIKRVVENYRTILNKSSENR"
     gene            complement(84355..84954)
                     /locus_tag="PC465_000079"
     CDS             complement(84355..84954)
                     /locus_tag="PC465_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2647420.1"
                     /translation="MENTLSEFLDNISNELSEFIASIDETSINKACELILEAEKNHGR
                     VHVTGIGKPGHVSGYISSLLSSTGTSAYILHGTEAVHGSSGQVVEGDVVIAISNSGET
                     QELKATLKTLKVNGAKIIGVSGNESSFLKNISDIFLFAGVKQEGDCLNKAPRASILAE
                     TIILQSLSVVLQYAKGLNTQQYLKWHPAGSLGKSIREGI"
     gene            complement(85012..86283)
                     /locus_tag="PC465_000080"
     CDS             complement(85012..86283)
                     /locus_tag="PC465_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HDF2647421.1"
                     /translation="MEFIISLLSTPAVLLGVVACIGLILQKKSAVEVFTGSSKTLIGF
                     LIFGIGASAMTGALQNFNKLFQHGFGITGVIASPEAATALAQGTYGFAVSCTLILGFI
                     LNLVFARITKFKNIFFTTGHSLFFSCVLVLIMKAHGFDNTITILIGGTILGFMSAALP
                     QFCQPFMRELTGGDEQAIGHFNMIGYGLSGYIGRLFSKHKDDTTETIEFPKWLSIFRD
                     FLMGLSIVMLILFYIATLKAGQAFTQEIAGSTHWLVFPLIEAFTFVAGMSILMSGVRM
                     FLAEITAAFVIISEKYIPGSRPALDVPTVFPYAPNAVIIGFISAYAAGLLAIAIMASF
                     PSIFPVVIIPAAHICFFSGGTAAIFGNTSGGWRGAIAGSFVVGLLLAFLPVILYPVYG
                     TLGIEGATFPNIDYNVVGSILHNILQFIKPI"
     gene            complement(86310..86597)
                     /locus_tag="PC465_000081"
     CDS             complement(86310..86597)
                     /locus_tag="PC465_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2647422.1"
                     /translation="MYKILIACRAGVGSSLMLKIKTQQIIKENNFPIEVEHGSLDSLN
                     GFNGDAVETLIDVAEELKNKNLKFDIIGIHNIVDRNEIKTALEKFLASKEG"
     gene            complement(86612..88699)
                     /locus_tag="PC465_000082"
     CDS             complement(86612..88699)
                     /locus_tag="PC465_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2647423.1"
                     /translation="MVVDKEIVSILQILLNSTLITTNGLQEESNSSKRQITYRINKIN
                     DMLKVKNVPLICLRADKDIIVRKETKKAIKEILEKNYSKNTYYFSKTERLLYMYLMLF
                     INMEDISINHFINSIKVSRSTVNLDFKDLIPKLEKKNIKVKNNRINGYYIVGNEMEIR
                     RVLIKNIIETLSNEKSSRVFDIFIKEYNLDSFEEAKKIILKLIKKYEITFVEDRLIEF
                     IYIFIFLKARMYSTRIVTQENVDIPNISVMSSMKEYKFAKELLEVYGSEDKIKPHNIM
                     YISAWILGISVGNYEEDTEDKDVISKIVNKMMTKFGYLSGVYYISQEKIFKQLYSHFR
                     PAYYRLLFKLPIYNPICEKVKEEYKLVYRIVSNAMKEFCGLFGEEIQEEELAYLTMHF
                     ATLFSNKKEFDGFRKRIALIVCSNGVGSSAILHAELTNLFPDLHFIPMSESVGLENIS
                     EPVDIVFTTNYNAEGLKTDVPVIKVSPVMTTKEKYKITREVYIQLGDIFLRQPKIDEV
                     MDIIKKYANVTSESILSSELLAYFTQIENFTSKEGEGPMLSEITNETLVKIKVKAKNW
                     EEAIRQSASVLVENNKVTEGYVDAMINSAKASGPYIVITKHVALPHARPEAGSKEIAI
                     GIATLDSPIEFGNNENDPVKYVFCLSAIDNNSHLRAMSELVELLEEDEFFKVLDSAKE
                     AKEIIDFIKTHEL"
     gene            complement(89330..90154)
                     /locus_tag="PC465_000083"
     CDS             complement(89330..90154)
                     /locus_tag="PC465_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2647424.1"
                     /translation="MRTEKSLKRPIASFIILTNIIFLPLFLLVVVTIMLKLPTVISDI
                     ALCISAWSSTFAFMILFKKIYPDKKFLVHVKDRFRNKLKFSTVSIIISIQVLIAVVVI
                     FILASKNHGIMPNFTVSSWGAFIYLFLKNLFAGSLGEELGWRGFVQNHLQKRHSPLKA
                     SIIVGFWWGMWHLPIWFTTGFKGLDLIKYIIFFMIAIISISIIMTTFYNLNKTLIIPI
                     VIHQLFNFLIGIINGDLIELINYYAMLYLIVAIVLVAINPGNALYKRFSKNTTQIL"
     gene            complement(90258..91052)
                     /locus_tag="PC465_000084"
     CDS             complement(90258..91052)
                     /locus_tag="PC465_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2647425.1"
                     /translation="MYTIGQVSKFLGISRDTLKFYEDKGLVNPKKNDENGYRIYNQVD
                     IYDIATINFYREIDIEIKKIQEIRKSKSINNLELLLEEKEQIILKEIEYKKLLLKKVQ
                     LVKEDCDKIKTYFGKYTIKEMKPLEVKGKIKHVTNYEEYEALKENTNNLKKAVTLTDL
                     RRVINFNEEGIIEEKFIIVREVDDYNKIIEGEVLSHPNCIYTIIEDGRWSTGGENIDN
                     KVEDRLREIAIENECELLGIVYVNILLTTYEEGIERIFLEIYAPIK"
     gene            complement(91586..92440)
                     /locus_tag="PC465_000085"
     CDS             complement(91586..92440)
                     /locus_tag="PC465_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase"
                     /protein_id="HDF2647426.1"
                     /translation="MAMGFEFKIMRSLIYVGLAKEEYRPKLMDWLYRHHIPDSISTFG
                     PYCTKYAFYQAYPTPNEGERFGARKMQLTEHYWLVDEHMPEMANRIMTEYMPMDVLRW
                     QGCIPDVENKRVHENVESGDAGRAVGGDNGCPPFIFAFVPINWEEDFRGKGRTVQDGP
                     NYRWQFMIKYPDGISKEEGEKWFYDEVVPYFTNCCYVNRFVSSKIMINYGATAFDRVS
                     ELWFEGEEEWYKAVVEETKSFIKKPEWAQEEEFPYLKPQFNIASVFLGDIATMDAYSQ
                     YRGYIPMR"
     gene            complement(92472..92984)
                     /locus_tag="PC465_000086"
     CDS             complement(92472..92984)
                     /locus_tag="PC465_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HDF2647427.1"
                     /translation="MDRKKKEILTLSMGIALLPPLWAVLAPYIGIKTGAVALICAGLY
                     VTNGNKQKDGLKIMFGFWCGDLWAVLAILIMGYMNFNQNLELFLTLSILGFFAVVIAS
                     LFEKIIFLPSWLCGWAIGLTVMTGENIINLQDICIQIAVAMAVGVWYVGAGVDLFTIY
                     ILSKDRKKGN"
     gene            complement(92977..93201)
                     /locus_tag="PC465_000087"
     CDS             complement(92977..93201)
                     /locus_tag="PC465_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647428.1"
                     /translation="MNEKPSFKQIEVILAVIFLVLTYYKVRLTPAFIVIFIPLYLSYF
                     AVSMIVNQIAIKLLEIRQAREATNYNIGNG"
     gene            complement(93261..94214)
                     /locus_tag="PC465_000088"
     CDS             complement(93261..94214)
                     /locus_tag="PC465_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDF2647429.1"
                     /translation="MKILGISFGTKNGNNDTMCKVALKGAKEAGAEVEFIQMSSINIK
                     HCTGCCACVKTLLSGKGSMCVLKDDFEWLLDKMKDADGIVVSDPIFEEGASGLFHTIM
                     DRFGPRADRGNNIIGTKVAEVIGGKIPDSRMLNDKVISFMGIGGSDWGTRVQCEHAML
                     ALIPMWKVIDNAWFPWAKELVMDDTRLVQVHQIGLNIVEAAKDFEKASYQGEEGVCPH
                     CHNRLFYLEPGTKKAICALCGIVGELDTISGKTIFSFPEEQLGHAHDTLPGKFIHGDD
                     IKKMEGHYAEVRKTQEFKERKTSYNFIEPLTKEKQAGVSLG"
     gene            complement(94242..95630)
                     /locus_tag="PC465_000089"
     CDS             complement(94242..95630)
                     /locus_tag="PC465_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647430.1"
                     /translation="MEDKFYAKGNGNNGYIKNLEVCSFNNLDGTCGMFQMALYKRDEK
                     YYLYGCCFGGNKKNGVMISDITDPYNPQFIKHFQMLDPKEYPTTTTPKIQIADDLMIV
                     AMSCGSGPGALVDQAKLANIKCEAGIRIYSLKEDPLNPKFLGYWDCGLKHVMGVHRFM
                     YNGGRYVHLSSDCVGFEGLIYRVIDIINPTNPVEIGKWWRPDQYADGYPNRTFDAGAP
                     HCPEFMDKGWLHGPPFVRDGKAYCGYGGAGLVVLDVEDLTRPRCLGELPFTPAFSSRL
                     AGARTHTALPLPGRDLVVVQNEGERFQFFKPDNITDVQAMNNIHMVDVSDPTKPTLIA
                     QFPYPEVPKDFPYPNFNVAGLGKPGPFGPHNLHEPMDNKPWLEQRGDRVYCCYFHAGL
                     RVYDVSDPYYIKELAYFIPPNPNKTPEESYFPGFPGPRLAVTEDLIVDDRGYIIIDAL
                     DDGFYILKMKED"
     gene            95904..96785
                     /locus_tag="PC465_000090"
     CDS             95904..96785
                     /locus_tag="PC465_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2647431.1"
                     /translation="MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQIN
                     VTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYE
                     KNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYK
                     TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGF
                     VPNVVQRSNNLNTIESLVSSNMGISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVV
                     WNKKNTNPALEKFISII"
     gene            complement(96973..97965)
                     /locus_tag="PC465_000091"
     CDS             complement(96973..97965)
                     /locus_tag="PC465_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDF2647432.1"
                     /translation="MNILAFGEIMMRLSVPDYKFLTQTNELNYIITGTGLNILSGLKN
                     FGYNTYMLTKLPNNNVGKASSANIRKLGVKDDFITYGGNHIGVYFLENGYGERPSEVT
                     YLNRLNSSFCESKLQDYDIDKCLEEMDIVHICGIAMQLTDSVKEIALELARKSYEKGI
                     KVFFDFNFRQSLNPERTYDDLVNDYKKILPYCHGLFASYRDINKILNIDSLNIKSSSE
                     LIKKEYDIDIVAGTMRRFDDMNNRFIKGYISNDDGYFESREYKLEIYDRVGAGDGYVA
                     GIIYSYLENMKSEDIVEFGVASSVLAHTTYGDNSLVSTGHVLRLMNNEKIDILR"
     gene            complement(97970..98725)
                     /locus_tag="PC465_000092"
     CDS             complement(97970..98725)
                     /locus_tag="PC465_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HDF2647433.1"
                     /translation="MERINMNCIPQYYKNRVCLNVLAGSIKNAKEVYDACDGHVLIGV
                     LSKNYSTVEVAIEDMKKYSKEIDNAISVGLGAGDPNQSNMVSQISKELQPQHINQVFT
                     GVATSRALLGQNDSIINGLVSPTGKPGFVKISTGPLSSKEKDGIVPIETAIAMMKDMG
                     GSSIKFFPMGGLKTKDEYIEVAKACAKHNFYLEPTGGIDLDNFKEIVQIALDAGVEKV
                     IPHVYTSIIDKETGETKVEDIGVLYKIMKELLG"
     gene            complement(98775..99884)
                     /locus_tag="PC465_000093"
     CDS             complement(98775..99884)
                     /locus_tag="PC465_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HDF2647434.1"
                     /translation="MSSIFEKYSVRRVINASGKMTILGVSTVDKEVIEAIGEGCKNFF
                     IIEELINKTGEYIANLLGCESALIVSSASAGIAQSVGAMIAKDDMSLVYNVNNPKKQV
                     KREIIIPKGHNVDYGVPVEVMIRLGGGEVVEAGYANMCNKEHIIREINENTAAIMYIK
                     SHHCVQKSMLSVLDAVQVAKEYNLPLIVDAAAEEDLNVYYELGADLVIYSGAKAIEGP
                     SSGLVIGKKKYIDNVKLQSKGIGRAMKIGKENIVGLTCAIERYISNDKVTLKEMEDKL
                     NPFIDKINTIKGVSASITRDSAGREILRGEIDFNEDIINKSTQQIINELRSGEIAIYT
                     RDYKANEGKIEIDIRSVTGSDLDTIYNRIKNIVES"
     gene            complement(99902..101035)
                     /locus_tag="PC465_000094"
     CDS             complement(99902..101035)
                     /locus_tag="PC465_000094"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HDF2647435.1"
                     /translation="MKIDILIKGGKTVDKSIIDIAILDDKIIEVKNQIDDSKYQANQI
                     INLDGEKFISAGWIDIHTHCYERLDLYKDYPDEVGIKSGVTTVVDAGTTGALDIGKFY
                     EDTKKYKTNVYALINIAKQGITSQDELSSMMNIDEYELKRAVKKYKDFVVGIKARMSK
                     SVVISNDVEPLKVAKRIKNELNLPMMVHFGSSPPTIEDIFDYMEKGDILTHIYNGKPN
                     GILRGNEVKKEIIEARERGIILDVGHGTESFSMDIAMKSKDAGIFPDTISTDIYIKNR
                     INGPVYNLSTTMEKFIYMGYSLEDIIDKVTKNAADAISLKNKGLIKEGYDADLTIFDV
                     VNEEKELQDSLNKSVITSTSIKPRAVVVNGEYLNIGKSIGENE"
     gene            complement(101037..102131)
                     /locus_tag="PC465_000095"
     CDS             complement(101037..102131)
                     /locus_tag="PC465_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDF2647436.1"
                     /translation="MERRLGISVYPEHSNMEDDKAYIKMASKYGFKRIFMCMLSITRP
                     KEEVKKHFKEIITYARELGFEVILDIAPNIFDILQISYDDLTFFSELNASGIRLDYGY
                     DGSKEAMISFNPYDLKVELNMSNDVAYLDNIITYKPNVNNIYGCHNFYPQRGTGLPYD
                     FFVRCSNRFKKYGIRTAAFVNSKYATIGPWNINDGLCTLEMHRNLDIATATKHLFATG
                     LIDDVIVGNAYASEDELKRMSEVNKYQVVFNVVTEEKTSEVEKTIMANEQHFRRGDIT
                     NQVARSTEVRKKYAKENFLKHDNTTIFKRGDVVIGNDDFGKYKGELQLILQDCADERK
                     NKVGRIKEDEIMLLDFIEPWSKFKLILEGE"
     gene            complement(102268..103569)
                     /locus_tag="PC465_000096"
     CDS             complement(102268..103569)
                     /locus_tag="PC465_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2647437.1"
                     /translation="MEKFASFLERKIMPVAAKISNQRHMRAVRAGIIATLPLTIVGSF
                     FTILLNIPIDAYMDFIAPFKAILDIPFRYTVGFLSLYATFGIASSLAKSYDLDTTGVG
                     MLAVMAFLVSTIVPTQVVEPVGGVIEAGRWMDMAKLNSPSLFGAIVTSLITVEIYRFM
                     KEKNITIKMPAGVPVEVSNSFTALLPTAVILMLFWVIRHILGFDISVALSAMLSPLKG
                     FLSGNSLGGGLLTVFLITLFWVLGIHGPAIMGPVIRPIWDMSIAENITAFTEGVSAHA
                     MPNIFTEQFLQWYVWIGGAGATLALVVMFMFSKSQYLKSLGRLGFLPGLFNINEPIIF
                     GAPIVMNPILGIPFIIGPIIMTILSYVLTITGVIPMMVARLPFAMPAPIAAVMSTNWS
                     ILAGILVLINFVISFAVYYPFFKVFEKQQLQREQEEMSENL"
     gene            complement(103793..104494)
                     /locus_tag="PC465_000097"
     CDS             complement(103793..104494)
                     /locus_tag="PC465_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2647438.1"
                     /translation="MLRNQPLYIQVVDILKQKILNNEYKIDENIPTERELEQEFGVSK
                     ITIRKAIEILESEGYVEKKSGKGTKVISNSLFNKLSKAESFSSILLSKGHKLFKETIS
                     IEKIINDTNSQVFSIFGEKCSKITRMYYLDSKPYIFFTHYIPFDENLTVESFNNENSL
                     YMYLYRRNINITRFEDEFFIEESELEVSKALNLAKDILLGRKRKTYDENDNIVELSFA
                     RYNTEVQNYVIKYEI"
     gene            complement(104758..105024)
                     /locus_tag="PC465_000098"
     CDS             complement(104758..105024)
                     /locus_tag="PC465_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2647439.1"
                     /translation="MDEKIIEISFNIIGYAGEGKGLAFEAIKEAKNGNIEKAKELLKE
                     SREVINKAHRYQTELIQNEASGNRTEISVILIHAQDHLMNGMNF"
     gene            complement(105072..105383)
                     /locus_tag="PC465_000099"
     CDS             complement(105072..105383)
                     /locus_tag="PC465_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2647440.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMESAAKENGIESQIWAIPESTIQN
                     EIEKCDVLLLGPQVRYVLPKAQEIAKPYNIPVEVINMMHYGTVNGEAVLNRAIELNNT
                     K"
     gene            complement(105532..106011)
                     /gene="rlmH"
                     /locus_tag="PC465_000100"
     CDS             complement(105532..106011)
                     /gene="rlmH"
                     /locus_tag="PC465_000100"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HDF2647441.1"
                     /translation="MNISIVVVGKIKEKYLKLGIDEFKKRLSKYCKLEIIELDDEKAP
                     ENLSVKEMEIIKDKEGKKILGKIKHNSYVIALAIDGKGLSSEELAKTMSDLAVRGNSS
                     LCFIIGGSLGLSDEVLGRADYRLSFSRMTFPHQMMRLILLEQIYRAYRINNGEPYHK"
     gene            complement(106079..108181)
                     /locus_tag="PC465_000101"
     CDS             complement(106079..108181)
                     /locus_tag="PC465_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC/EAL
                     domain-containing protein"
                     /protein_id="HDF2647442.1"
                     /translation="MLKRNFENVEDNKILYSIKQGMILAIPAIMTGSTALVILNLPIK
                     AYQEYLSGLFNGEVTNILNFINDSTLGIISLIILLTISYSYGKIYGSKYTVLVPIVAM
                     CSFLVFSHGNELNSYIEIFKTKWLFTSIIVSMTSSVLFVKLTESFVTSVKFHTEGADA
                     DFNMVVSAIVPFIIVVFLFSIFRVIMISLIGSSNFQDIFYNLFSNVFNKMGTNLMSAL
                     LFIFLMHFMWFFGIHGSNVLDTVAKNLFENSMAININLVNNNQLPTEIFTKTFFDTMV
                     LLGGCGSLLCLVIAIFLSEKRINVRKLAKIASIPALFNINEMLVFGIPIVFNYIMFVP
                     FVITPIILTITSYVAMSTGIVPCTVSAVEWTSPIFLSGYMSTGSIRGSLLQVFNLCVG
                     VMIYIPFIKMSQNRYTYMFKNNIENLTNLLKRYELTGEQPNLLNHNGKIGSISKMLAS
                     DLKFAMKRGEIELFYQPQVNYNGNVVGAEGLLRWKHSIGGFIYPPLVIILAKEEGFLD
                     ELGEYIINKACIDLKKSEKLLRNPVKFSVNISPDQLDDPKLPEQIKNIISSNDINPNM
                     LGIEITEQIALSGSQIIIERINAIHNLGIKLIMDDFGMGHSSLIYLQNNNFDIVKLDG
                     SLVKEILTNKRSSEIIMTIVNLSKNLDFDIVVEYVENIDQRDKLYGLGCEIYQGYYYS
                     KAIPFEEFVEYANQEREI"
     gene            complement(108194..108991)
                     /locus_tag="PC465_000102"
     CDS             complement(108194..108991)
                     /locus_tag="PC465_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2647443.1"
                     /translation="MLKYCSVGSGSSGNCHYIGYKNTNILVDAGLSGKRITTGLKDIG
                     VDADKLKGIFITHEHVDHIKGAGILSRKFDIPVFANIKTWCSMKDKLGDIKDKNMKVF
                     ENDKTYSLGDIIVRPFSIEHDASDPVGYNFYTESDEKMSIATDIGCITQNIKKHLYKS
                     KLVVLESNYDPNMLMMGSYTYALKKRVMSSTGHLSNEDAANFCVELINEGTESILLAH
                     LSKENNFPELAYETSKGVLASNDIVVGQDVKLDVLSRNDVSNVYEMK"
     gene            complement(109093..110556)
                     /locus_tag="PC465_000103"
     CDS             complement(109093..110556)
                     /locus_tag="PC465_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HDF2647444.1"
                     /translation="MVIKFNQKVRRTLSVAILFMVLIIGCFIEKDDSLETYKEKTNSK
                     INQYNMDVIFDDETKRLMCNQNVDYINNTKSNIDKIYFHIYPNAFSKKDFAPFEKSEM
                     TRAYPNGFNEGYIDIKNILNNNSKMEYKIKGDKNDILEIELGKELKPNERMSLDIKYN
                     VKIPNSIGRFGYGENTINVTNWFPIACVNDERGWNLKSYETIGDPFYSETSDFHVKLL
                     IPNKYKIAHTGKLIDDKHDNKKMLYEIEAENVRDFAFILSSKFDVNKVDSKGVAINTY
                     NLNKKLSKKATEVAKDSINIFSELFGKYPYKEFSVVASDFFIGGMEYPMLVMIDQSLY
                     NEKNEFLLEYVIAHETAHQWWYSAVGNDEISEPWLDEALTEYSTIVYFEQKYGKDMAN
                     KLIKTMEIQTKSYLSENIFKPANEYKNSTEYSLNVYTKGAIAFNEIRKEVGDKVFFET
                     LNEYYNKYKHKNANGRAFVELWNSKGVDINKIISECK"
     gene            110681..111739
                     /locus_tag="PC465_000104"
     CDS             110681..111739
                     /locus_tag="PC465_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HDF2647445.1"
                     /translation="MFFKESNEIDLGEITIPNIFIDIFMPMADGLYVKVYLLGYRQAC
                     DITSNPKFDNNSIAKNLNIPLSDVLSAWKFWEEKKIIKIHDNGEYDNFNYSIEFLDLK
                     NFYIENILSNNSSIKSNTDKVVSTSENPSIRKMFNSINKIVGRYLDPSEKMSIMDIMN
                     KYNMSPDMILCAYEYVKDKTGTSKPVKYIEGIIRNWYDSNLYTPKDVEESFLVRSERY
                     ILYKTIFNELGFSRQPSKSEKELMDTWFDKFNMDIDLIINACSKSKNISNPSISYING
                     IIKNWNEKNIKNLNDLKQKEEERIVKENINKKQINTTQNNNTYKKTKFHNFNETFTQY
                     TSDELDEIIKKSQKEKFK"
     gene            111748..112740
                     /locus_tag="PC465_000105"
     CDS             111748..112740
                     /locus_tag="PC465_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2647446.1"
                     /translation="MNEDKIRKILAKYAKRRDDNELLLEHRKNEVYNRIPEIKSIDDE
                     ISKIGLSLAKIVLLNPKSKDEIVKKTKENIESLKVKKERLLAESNIPLDYLEIKFQCI
                     SCKDKGFLPNGEKCSCLKQEIVNEAYKMSNLDRILSQENFSNFNLNIFSPKKGSDGEI
                     SPRENMLNNLSICENFVHDFKKDNSENLLFYGSTGLGKTYMCNCIAKELLDKGNVVIY
                     QTSFRILDILEDYKFRRDTNNQISEDNYKNLFDCDLLIIDDLGTELNNSFTSGEIFNI
                     VNTRLVAGKKIIISTNLTPSQIGNTYTQRTLSRILDKFRILEFTGDDLRWERFK"
     gene            complement(113123..113197)
                     /locus_tag="PC465_000106"
     tRNA            complement(113123..113197)
                     /locus_tag="PC465_000106"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(113163..113165),aa:Thr,seq:tgt)
     gene            complement(113231..113306)
                     /locus_tag="PC465_000107"
     tRNA            complement(113231..113306)
                     /locus_tag="PC465_000107"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(113271..113273),aa:Val,seq:tac)
     gene            complement(113311..113385)
                     /locus_tag="PC465_000108"
     tRNA            complement(113311..113385)
                     /locus_tag="PC465_000108"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(113350..113352),aa:Glu,seq:ttc)
     gene            complement(113392..113467)
                     /locus_tag="PC465_000109"
     tRNA            complement(113392..113467)
                     /locus_tag="PC465_000109"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(113432..113434),aa:Lys,seq:ttt)
     gene            complement(113793..115082)
                     /locus_tag="PC465_000110"
     CDS             complement(113793..115082)
                     /locus_tag="PC465_000110"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HDF2647447.1"
                     /translation="MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLV
                     VEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEMFKTDNISTENIKISDRA
                     HVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL
                     KAQIDAKNEIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKV
                     LFEGAQGTLLDLDLGTYPFVTSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEG
                     PFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNGLTSISFMLLDV
                     LTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPE
                     NAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRRNIFA"
     gene            complement(115164..115472)
                     /locus_tag="PC465_000111"
     CDS             complement(115164..115472)
                     /locus_tag="PC465_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647448.1"
                     /translation="MEKISLKYIYPNIIKVLDEINLFRVIDNNLRESIVVYANNVDNQ
                     YHINMTNTNFGNIINICKLEKLLDVDKFMEKVIKYEKEIIEKEEFSKIEEYMLNIGEY
                     "
     gene            complement(115677..117005)
                     /gene="dnaB"
                     /locus_tag="PC465_000112"
     CDS             complement(115677..117005)
                     /gene="dnaB"
                     /locus_tag="PC465_000112"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HDF2647449.1"
                     /translation="MEDMTRIPPHSVESEQSILGSILLDKDAIITVTETIKPDDFYKE
                     AHKIIYECMITLSNKGEPIDLITLTEELRKQGHLNDIGGISYITSLSTIVPTTSNVKY
                     YADIVKEKSVLRKLIKASNEIINLGYSGATKIEDVLEQAEKSIFDISQEKTSDDFKSI
                     NLVLMDAYDMIEKLYTNKSDVTGITTGFKDLNKKINGLQRTDLILIAARPAMGKTAFS
                     LNLVQNAALKGDASVAVFSLEMSKEQLVQRMLSSQSSVELKKIKTGTLNDNDWPRIID
                     AMAVLSDAKIHIDDTPGIKISELRSKCRKLKIEKGLDLVLIDYLQLMEGEGNNESRQQ
                     EISKISRSLKILAKELNCPVVALSQLSRAPEQRADHRPMLSDLRESGAIEQDADIVMF
                     LYRDEYYHADSESKNIGEVIIAKNRHGETGSVELVWLGEVQRFGDKLRDL"
     gene            complement(117024..117473)
                     /locus_tag="PC465_000113"
     CDS             complement(117024..117473)
                     /locus_tag="PC465_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HDF2647450.1"
                     /translation="MKVILLKDVKGTGKKGEMKEVSDGYARNFLFPKKMAVQADSVAI
                     KELNEKNKSKEIKAQKEYEEAVLLGKQMEEINIEIYSKAGEGGRLFGSITSKEIAEQL
                     KKQKDIDVDKRKILLDEPIRSLGSTFVEIKIHQKVTTKIRVDVKEKQ"
     gene            complement(117474..119468)
                     /locus_tag="PC465_000114"
     CDS             complement(117474..119468)
                     /locus_tag="PC465_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HDF2647451.1"
                     /translation="MSNKQAFKLNMPEINLYIIVIGISSIILLYYNLYVGCLFFCIFV
                     YMVFHNWRTTNIRRHEWTEYIQNLSLDIDETTKKAIINLPIPLCILEFDGNISWYNGK
                     FYDMIGQKDLLDKNIEDIVKNLNLRKVLNENKEMYTEINYKEKEYTIIYNVIKNDQEK
                     NPKYLMILYWIDKTEYLKVKQNYDDEKNAMMLIQVDGYDEVLKSAAEDKRALINVEVE
                     KILSALELNSNGALRRTSKDKFFLVMHKKELKKLEAEKFSILDTIRHIDYGNNLPVTI
                     SIGIGIDGDTLNENLKLATGALDLALGRGGDQAVVKTKDKFVFYGGKSKAVEKKTKVK
                     SRLIGHALREVIQQSDQVYIMGHKYPDMDAMGAAVGVYDICKSCNKTANIVLQSVNES
                     IEIFINKINENNYYKKLFIGKEEAIDNCTKNTLVVVVDTHRPNYTECEELLKLSEKVV
                     VIDHHRRGVEFINDAVLLFHEIYVSSTCEMVTELVQYMDEDVTINKLTAEGLLAGISL
                     DTKNFAFKTGVRTFEAASYLRKVGADTIEVKKFFNSDVKDFIIKAEIIQSTKIINNRI
                     CLAYSSTEIDSINVIIAQTADELLNIKEVEASFVLGEKDDTIFISARSLGQINVHVLM
                     EKLGGGGHIDIAGAQLKNVSLKEAYKMVNKIIEEYLEEEE"
     gene            complement(119479..120435)
                     /locus_tag="PC465_000115"
     CDS             complement(119479..120435)
                     /locus_tag="PC465_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HDF2647452.1"
                     /translation="MNNKIRLSKAMSIIVLAIIIALVIAYIPMLGIFSMLAAVPYVII
                     GAITDRKYSLISILVTFCVLILFADISYALNICIMYSLPGIVIGKMLKRSFEQEDSNK
                     FEPIYGGTIIFVLSMLVYFFVLKTFLNVNLLDEVSKMISEIVNIQKNSFSATELKVFD
                     KMKPDEIVSYFTNMLPMMLFLQGLLSAFVTYYLSVFFIKRITKMNIRFPKFADFYLPG
                     NAILTTFLLYLLVLFIQIIGSKLYTELIMTNLQLVFNLMFVIQGIAVCIYFLKKWIRQ
                     GPNKIMFFSGIILCLFGFMGISFVGMVDSIIDFRKVRSYKST"
     gene            complement(120443..120763)
                     /locus_tag="PC465_000116"
     CDS             complement(120443..120763)
                     /locus_tag="PC465_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HDF2647453.1"
                     /translation="MKIDKGSEITRNIKIIEWMKTEILMSVSDLFNLLFKGVKPLDEA
                     IQDTLANIIMITYLLAKRLGISFRDVDYKVKEKIKIGIDEDHSVERWYGDLSNLKKHM
                     DNRE"
     gene            complement(120906..121133)
                     /locus_tag="PC465_000117"
     CDS             complement(120906..121133)
                     /locus_tag="PC465_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HDF2647454.1"
                     /translation="MMNKKRRKKKRVCQFCADKNAKIDYKSTQRLQKYITERGKILPR
                     RISGTCAKHQRELTVAIKRARNIALLPYTLD"
     gene            complement(121152..121586)
                     /gene="ssb"
                     /locus_tag="PC465_000118"
     CDS             complement(121152..121586)
                     /gene="ssb"
                     /locus_tag="PC465_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2647455.1"
                     /translation="MNQVVLVGRLTRDPELRYIPGTGTPVASFTIAIDRDYVKKDGSK
                     ETDFIPVEVMGKSAEFCANYITKGRLVALQGSIRVDNYQTQSGEKRTFTKVSTRSVQA
                     LDSKNKSENSYRESAPAFEPSFEPQGLDPQGFQAIDDDDIPF"
     gene            complement(121623..121901)
                     /locus_tag="PC465_000119"
     CDS             complement(121623..121901)
                     /locus_tag="PC465_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HDF2647456.1"
                     /translation="MRNYELVYVVKPNSDEEVREAILNKVKEVVATDGEIVKVDTWGT
                     KKLAYPIAKFTEGFYVLVNFKSAVDVPKEIDRNLKINENVIRHMIVVA"
     gene            complement(122115..123311)
                     /locus_tag="PC465_000120"
     CDS             complement(122115..123311)
                     /locus_tag="PC465_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2647457.1"
                     /translation="MAVKYAKRMQGLQGSEIRELLKLTQQPQIISFAGGMPAPELFPV
                     EEMKKVSVAVLEENGRSAMQYTTTEGYEPLREKIAARMNDKNKTNVNKDDILVTSGSQ
                     QGLDFAGKVFIDEGDVILCESPSYIGAINAFKSYQPKFIDVPTDSDGMIMEELEKILE
                     TTDRIKMIYVIPDFQNPTGRTWPLERRKKFMEIVNKFEIPVIEDNPYGDLRFEGETLP
                     SLKSMDTKGLVIFLGTFSKIFCPGYRLGWTCASPEILSKFNFAKQGADLQASTISQME
                     VSKFMDMYDLDAHVDKIKAVYVKRRDVMLKTMEEEFPEGLVFTHPEGGLFTWVELPSN
                     LNAKELMPKCLDKNVAYVAGGGFFPNGGRENTFRLNYSNMPEEKIIEGIKNIAAVLKE
                     AMGVEA"
     gene            complement(123414..123599)
                     /locus_tag="PC465_000121"
     CDS             complement(123414..123599)
                     /locus_tag="PC465_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HDF2647458.1"
                     /translation="MPMDLKIGDIVELKKQHACGCKEFEIIRTGMDIKIKCTRCSRLI
                     MLDRETLEKRVKKLIKK"
     gene            complement(123614..123877)
                     /locus_tag="PC465_000122"
     CDS             complement(123614..123877)
                     /locus_tag="PC465_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HDF2647459.1"
                     /translation="MNQMYIVSFNSTHHAIRSEKLFGENSLKVMALPTPREITASCGI
                     SIKFSFEDMEKIKTILVENNVDIKGIYCISKLENGSKEVEKLD"
     gene            complement(123950..124552)
                     /gene="yedF"
                     /locus_tag="PC465_000123"
     CDS             complement(123950..124552)
                     /gene="yedF"
                     /locus_tag="PC465_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HDF2647460.1"
                     /translation="MSIKIDARGLACPKPVINTKRELDNLEEGVVVTIVDNETAKENI
                     LKLAKSLSCEANIVDEKENFISIEIRKGKNILDKQNVVDNKESELDNTCIFISSDKMG
                     LGNDELGKVLIKGFIYTLTESKPYPKYVLLVNGGVKLSAENEETIENLKILENMGVEV
                     LSCGTCLDYYNLKDKLQVGTVTNMYTIVETLKNASNTISI"
     gene            complement(124657..125949)
                     /locus_tag="PC465_000124"
     CDS             complement(124657..125949)
                     /locus_tag="PC465_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2647461.1"
                     /translation="MEILSLGEKIKKLRKEKNMTLKELAGDRITAAQISHIERDKSHT
                     SYELLEYLGDKLDVSVEYLLETKEMQSKKITDNLILQSEIYIKENELNKAEDQIKEVL
                     DICKRYDLMENYGRCNFLMANINLKKSNYNDAIENFEKALYFFIKNSDSENILKCYLN
                     IGKIYMQEDFYKGAISHFNFAEEILSESKFEDVNIHKELYSKMAYCYIKLDNPNMSLK
                     YIEKINEIDNRNDRKEDVDILVLKANNMLEIGKYEESRDYFKKALKILESEDNKTGLA
                     NVYLTICDVYRKIGETDRVLEYSQKVYDIKKNDEDEYMMSGLFKIIEAYIDKEDYDLA
                     RKYCKIALASSIKNKNKFNEYKALRFYANMYKNQNEVTLAIEYLIKCIKIVSDLGNNR
                     ILANLYIDLGQLYSNISKEKELEYYQKGVFMYKNLEIM"
     gene            126209..126784
                     /locus_tag="PC465_000125"
     CDS             126209..126784
                     /locus_tag="PC465_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HDF2647462.1"
                     /translation="MKNKKIMLVLSILSISIFAVGCTNAQNGSDSSKKETKSNTNVEQ
                     PKEENNTEKEVPNNKAKPTPKEETKAQSATIYSFDVDKTDLIENKVDLNKIDENTLFE
                     ELQKLKVVPESAKLNSFTTKDIDGVKTGILDVSSDFTKSNLGSDAETLMLDSVARTYI
                     KNMNVEQIKITVDGSNYESGHIVLEEGDYLK"
     gene            complement(126918..128060)
                     /locus_tag="PC465_000126"
     CDS             complement(126918..128060)
                     /locus_tag="PC465_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HDF2647463.1"
                     /translation="MIYLDNAATTYPKPERVYNAVLDCMKNYCANPGRAGHKLAMRAA
                     REIYDTRENIAKLFNVSNPMNIVFTSNATDSLNLAIKGVLQEGDHVITTSMEHNSVIR
                     PIKALEKRGIENTVVKCDYEGFLDYEDLEKSIKNNTKLIVTTHASNVCGTLIDIKKVG
                     EIAKKHNILFLVDASQTAGVYDIDVNECNIDMLAMPGHKCLFGPQGTGILYVREGLNL
                     NILKEGGTGSKSEEIVQPELFPDKYESGTHNTPGIAGLNQGILFIFERGINNIRQHEE
                     ELCQYMIDKLEEVPDIKIYGPKDSKKRASVIALNIGDMDSGEVTFLLDSDYNIATRSG
                     IHCSPLAHTTLGTLKQGAVRFSIGYFNTKDEIDKAVEALKKISKNK"
     gene            complement(128093..128956)
                     /locus_tag="PC465_000127"
     CDS             complement(128093..128956)
                     /locus_tag="PC465_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HDF2647464.1"
                     /translation="MENKSKRSNRLGRGLSALIPEIKGETSEKEIVNIDIDKIYPNEV
                     QPRKQFDEEKIKVLSDSIKNYGVLQPIVVKMDENNKYMIIAGERRFRASKLANKNQIP
                     AIIKDIDMKDIMEIALIENLQREDLNSIEEALAYKSLIEHYNVTQEEISEAVGKSRPH
                     ITNTLRLLNLGQDVIEMIDSGRITAGHGKALLRIADKDLQLQIAKKIEEEELSVREVE
                     NIAKKISENKQEEPKKSKPKDVFILDVEDKLRNIFGTKVNISKGKKKGKIEIEYYNDD
                     DLNSIVSMLLE"
     gene            complement(128958..129731)
                     /locus_tag="PC465_000128"
     CDS             complement(128958..129731)
                     /locus_tag="PC465_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDF2647465.1"
                     /translation="MGKVIAVFNQKGGVGKTTTNVNLSASLGTLGKKILVLDLDPQGN
                     TTSGYGINKNEVENTIYEIMLDGLHIKEAIISTEFENIDVVPSATELSGAEIELTSKT
                     NREYILKNSIKAVIDEYDYIFLDCPPSLGMLTINCLTAVDSVLIPIQCEYYALEGVSQ
                     LMETIKLVKSRLNADIEIQGVVLSMFDGRANLSIQVVEEVKKYFKGSVYTTLIPRNVR
                     LAEAPSHGKPVIYYDKRCRGSVAYLELAEEFIDLEEEEW"
     gene            complement(129866..130651)
                     /gene="noc"
                     /locus_tag="PC465_000129"
     CDS             complement(129866..130651)
                     /gene="noc"
                     /locus_tag="PC465_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HDF2647466.1"
                     /translation="MEDKRVMEIPIEDVVPNPYQPRKIFSQVSLEELSNSIKVYGIIQ
                     PITVRAKDGKYELIAGERRLRAAKLAELKTIPAIINNMNDESSAVLALLENLQREDLN
                     FIEEAIGYENLIKEHAFTQQQLAEKLGKNQSTVANKLRILKLPNDIKMKLIENNLTER
                     HARAFLKLPSEDLMQSVLDKVIKNELTVKKTEKLIQDVLEETKVQEEPDKKQNIKGAM
                     SIRIYINTIKQAFDAISNTGIDAKYNEIDKGDYMEVVVKIPKK"
     gene            complement(130814..131533)
                     /gene="rsmG"
                     /locus_tag="PC465_000130"
     CDS             complement(130814..131533)
                     /gene="rsmG"
                     /locus_tag="PC465_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HDF2647467.1"
                     /translation="MNNIELLKNGIEGFNIDTNDSMLEKFKIYREILVDWNKKMNLTG
                     IEDEKEVYIKHFLDSISAVKNGYIKNGMSIIDVGTGAGFPGIPLKICLDSLELTLLDS
                     LNKRINFLEEVSRVLELDNITFIHGRAEDFGKNEDYREKYDVATARAVAGLPILMEFC
                     VPFVKVGGYFICLKGPNANLELEESQKAIDVLGLEYIEKIDVELPEVDLNHNILVFKK
                     VMETPVKYPRKAGKPAKNPIK"
     gene            complement(131526..133421)
                     /gene="mnmG"
                     /locus_tag="PC465_000131"
     CDS             complement(131526..133421)
                     /gene="mnmG"
                     /locus_tag="PC465_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HDF2647468.1"
                     /translation="MIKFEAGKYDVIVVGAGHAGCEAALATARMGYKTLIITMSLDSI
                     ALMPCNPSIGGTGKGQLVKEIDALGGQMGLNIDKTYIQSRMLNTAKGPAVHSLRAQAD
                     KFKYHEEMKKTLEDEPNLDIAMDEVVEILHEGNVVIGVGTKLGCSFKSKAVILATGVY
                     LNSKIYMGEVAFYEGPNALGYAKYLTDSLVELGLRMRRFKTGTPARVHRDSIDFSVMS
                     LQEGDEKVTPFSFMNENIEKKQEPCYLTRTTEETQKVILDNLKRSAMYSGVIESTGPR
                     YCPSIEDKVVRFSDKTSHQLFIEPEGLNTKEMYIQGISTSLPFEVQLDMYKTIKGLEN
                     CKIMRPAYAIEYDCVDPTQLKISLEIKGVENLFSAGQFNGTSGYEEAAAQGLMAGINA
                     VRKIEGKEPFVLDRSEAYIGVLLDDLVTKGTNEPYRMMTSRAEYRLYLRQDNADMRLT
                     QKGYDIGLVKKDRYERFLNKKAAVEKEFERLKNERVTPKEVNSLLEEKGATPIKVGIS
                     LYEFLKRPEVTYELLEELGKGAGDDVSREVKEQCVIITKYEGYIEKQLKQIDQFKKLE
                     NKKLDEKINYSSIEGLRLEARQKLDDIKPISIGQASRISGVSPADISVLLIYLEQIRR
                     TRGGKGE"
     gene            complement(133516..134895)
                     /gene="mnmE"
                     /locus_tag="PC465_000132"
     CDS             complement(133516..134895)
                     /gene="mnmE"
                     /locus_tag="PC465_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HDF2647469.1"
                     /translation="MFIDDTIAAIATAPGEGGIGILRISGEKALKVAEEIFKSMSGKS
                     IEEYNKRTLIYGNIVDNENIIDEVLLAYMKGPNSYTGEDVIEINCHGGFISVKKILEL
                     ILSKDVRLAEAGEFTKRAFLNGRIDLSQAEAVIDVIKAKTDIAHEVAQNQLEGSLSKK
                     IRELRDKVTEILAHVEVAIDYPEEDIEHITYQTLKEKTDELKKDIKKLYDTAESGKIL
                     REGLKTVIVGKPNVGKSSLLNSILGENRAIVTDIPGTTRDVIEEFVNIKGIPLKIVDT
                     AGIRDTDDIVEKIGVEKSKESFTSADLIVMVLDASRKLSEEDIEILEKLKDKQTIVLL
                     NKNDLKQEIEEEKILKYVENNSIIKISALQQEGIEELQDKIESMVYKGSIKNNSSLVV
                     TNSRHKDALSKAYKSATDALIALEQSMPFDFVEVDLKNIWDYLGYINGDTVTEDLLDN
                     IFHNFCIGK"
     gene            complement(135007..135636)
                     /locus_tag="PC465_000133"
     CDS             complement(135007..135636)
                     /locus_tag="PC465_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HDF2647470.1"
                     /translation="MRKSLKLIKSKSKEEAISKAIAELNLKAEDIEVEILENPSKGFL
                     GFIGAKDGTYEIFVIEREVDVAKNFIEVMLKNANVDAKVNVSQKDNLIMVDIEGKEAA
                     SLIGRRGETLDSIQFLTGLALNKINKDSHTRVLVDIENYRSKREESLIRYANKVAREV
                     AKTRKTKKLDYMNPYERRIIHSALQNDKYVITYSEGTDPYRRLVIECKR"
     gene            complement(135605..136312)
                     /locus_tag="PC465_000134"
     CDS             complement(135605..136312)
                     /locus_tag="PC465_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDF2647471.1"
                     /translation="MNIIGNFLGLILKVIFEFVNHYGISIILFTILVKIILLPLTIKQ
                     TKSTKAMQDIQPRIKEIQEKYKNKPEKQNEEIVKLYGEAKINPLSGCLPLLIQFPILI
                     GLFSVLREPVAHGVFANKAAFLAADNGFLWIKSLTSPDYVLAVFSGASAYVMQKVMTP
                     KDQLQGSMKVMTYVMAGMSFYWGFIFPAGLTLYWTVSNLFSIAQYYLIMNPLKAKLAA
                     NSKEEKVNEKKPKINKK"
     gene            complement(136344..136595)
                     /gene="yidD"
                     /locus_tag="PC465_000135"
     CDS             complement(136344..136595)
                     /gene="yidD"
                     /locus_tag="PC465_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HDF2647472.1"
                     /translation="MNKIIYILKEISKYLSNLCIYLVRFYQKYISPLKGPTCRFYPTC
                     SQYSIEAFKKYGFVKGMYLTIRRILKCHPFHPGGYDPLK"
     gene            complement(136627..136971)
                     /gene="rnpA"
                     /locus_tag="PC465_000136"
     CDS             complement(136627..136971)
                     /gene="rnpA"
                     /locus_tag="PC465_000136"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HDF2647473.1"
                     /translation="MDFNRTKGLKKDSDFRKVYKHGKSFANKYLVIYILKNKSDYSRV
                     GISVSKKVGKAITRNRVRRLIKEAYRLNIDEKIKPGYDIVFIARVSSKDATFKDIDKS
                     IKNLVKRTDISI"
     gene            complement(137049..137186)
                     /gene="rpmH"
                     /locus_tag="PC465_000137"
     CDS             complement(137049..137186)
                     /gene="rpmH"
                     /locus_tag="PC465_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HDF2647474.1"
                     /translation="MSKRTYQPKKRQRSKEHGFRKRMKTSNGRNVLKRRRAKGRNRLT
                     H"
     gene            137842..139164
                     /gene="dnaA"
                     /locus_tag="PC465_000138"
     CDS             137842..139164
                     /gene="dnaA"
                     /locus_tag="PC465_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HDF2647475.1"
                     /translation="MMDIVSLWDKTLQLIKGDLTSVSFNTFFKNIVPLKIHLNDLILL
                     APSDFNKDILENRYLHLIEDAISQLSLKKYNIKFVLSEKEVADLNSDSTDLNYRVLYP
                     NLNPKYTFDTFVIGNSNRFAHAACVAVAESPAKAYNPLFLYGGVGLGKTHLMHAIGHH
                     IVSQKKDSKVVYVSSEKFTNELINSIKDDKNEEFRNKYRNVDVLLIDDIQFIAGKERT
                     QEEFFHTFNTLHEANKQIIISSDRPPKDIPTLEDRLRSRFEMGLITDIQAPDFETRIA
                     ILRKKAQLERIDVPNEVMSYIAKNIKSNIRELEGALTRVVAYSSLSNRVISFDLATEA
                     LKDIITTSKNEEINVLRIKEKVSSVFNLKMEDFNSKKRTRSIAYPRQIAMYLTRELTD
                     LSLPKIGEEFGGRDHTTVIHAHDKVSKDIEESEEIKTKIDKIISDLKG"
     gene            139406..140512
                     /locus_tag="PC465_000139"
     CDS             139406..140512
                     /locus_tag="PC465_000139"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HDF2647476.1"
                     /translation="MKIICNQKILANRIGIAQKAINGKTTIELLKGILISTEEGQLKL
                     TGYDAEIGIETYVQAEIIEKGDVVVDARLFGDIIRKLPDSFVEIETDSENNIYINCVN
                     SRFKIKGYAAKEFPKLPELNEEDLYSIPQEILKNMIKQTVFAISQDQTKPVLMGELLE
                     IVDRNLNLVAIDGYRLAVKSCSVDSLTENIKVIIPGKTLIDVNSLLSGEDNVKVGFNE
                     KNAIFIINDTKIITRLLEGDFIDYKKLLPREHNSRVKLNTKELLNSIERASLLSQSEK
                     NNLIKLSIRDKVMAITSNTEKGNVYEEVEIDLDGDYLDIAFNSRYFIEGLKNIDNEEI
                     FIEFTTNVNPCIIKPTDDVNYIYLLLPVRISSNI"
     gene            140649..140855
                     /gene="yaaA"
                     /locus_tag="PC465_000140"
     CDS             140649..140855
                     /gene="yaaA"
                     /locus_tag="PC465_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HDF2647477.1"
                     /translation="MTEITIESEYIKLDQFLKLAEIASTGGHAKFLIQEGLVTVNDEI
                     ELRRGKKIKSGDIVEIEGTKIKVL"
     gene            140873..141988
                     /gene="recF"
                     /locus_tag="PC465_000141"
     CDS             140873..141988
                     /gene="recF"
                     /locus_tag="PC465_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HDF2647478.1"
                     /translation="MKLKSLQLVNFRNYKKLHLEFNGKVNLLVGKNGQGKTNIVESIY
                     MLSFGKSFRTNKDKEMVRFNSENLYIGGSFSKYNKYSLIELIIGKDKKGIRINKVPLQ
                     KIQELLGNLNVVIFSPEDLRLVKEGPKERRAFIDKEISQIIPKYYKYLTNYNKTLSQR
                     SRVLKNIHVDEALLDVYDDTLAKYGSYIYILRRDFIKKIANISENMHMNLTNGVERLS
                     IRYKNQINITDEDTIDTVYNKFLAKLSSNRPNDIESKTTRYGIHKDDLNIFINDLDAR
                     LFGSQGQQRTASISLKLSEIELIKNEVEEYPVLILDDVFSELDEARQKLLVNNLSNVQ
                     MFITSAEVSHKKIFDEKNVTIFNIENGDVISIENGGN"
     gene            141989..143890
                     /gene="gyrB"
                     /locus_tag="PC465_000142"
     CDS             141989..143890
                     /gene="gyrB"
                     /locus_tag="PC465_000142"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003226808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HDF2647479.1"
                     /translation="MKQEYGASQIQVLEGLEAVRKRPGMYIGSTSPRGLHHLVYEVVD
                     NSIDEALQGYCSDIYVSINEDGSVLVKDNGRGIPVEIHPKTGKSTLETVLTNLHAGGK
                     FGGGGYKVSGGLHGVGVSVVNALSKWMVAEVYLNGKIYKQTYEKGLPTSKLEVVGESQ
                     DKGTMIQFMPDETIFDEIEFKYETLEYRLRELSFLNKGIKIVFEDKREGQEKRKEFHY
                     TGGLVEYIKYLNKSRTGIHDDIVYIDKKVDDCFVELAMQYTDGYTENIYSFANNINTH
                     EGGSHLSGFKAALTKTVNDYAKRNKFLKENDVNLLGEDIREGLTAVVSVKLPEPQFEG
                     QTKTKLGNSFMRGIVDSVTVDELGSFLEENPSTARIIVDKALRAQRAREAAKKARELT
                     RRKSVLESTSLPGKLADCAEKDPSKSEIFLVEGESAGGSAKQGRDRNSQAILPLRGKI
                     LNVEKSRLDRILSSDEIKNMITAYGCGIGEDFDIDKARYHKIIIMTDADVDGAHIRTL
                     LLTFFFRYMRPLIDEGYVYAAQPPLYKVTKQKKEHYVYSDKELNILLDEIGRNGVELQ
                     RYKGLGEMNAEQLWETTMNPETRTLLQVTVEDAAIADEVFSMLMGDKVAPRKEFIEEN
                     ARFVRNLDI"
     gene            143910..146336
                     /gene="gyrA"
                     /locus_tag="PC465_000143"
     CDS             143910..146336
                     /gene="gyrA"
                     /locus_tag="PC465_000143"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HDF2647480.1"
                     /translation="MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVH
                     RRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHGDVAVYYAMVRMAQDFSTRALLV
                     DGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA
                     RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPT
                     AAIIMGKESIAEAYRTGRGKVKVRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIA
                     ELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYKHSQMEDTFSIIMLA
                     LVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVI
                     SLIRASKTGQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKIN
                     RLKEILADERLLLNVIKDEITIIKENYSDERRTEIRHAEGEIDMRDLISDEEIAITLT
                     HFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNKGRVFKL
                     NAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKR
                     EEFKNINKSGLIAIGLRDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTA
                     MGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNI
                     SEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVV
                     SIAKINIEEE"
     gene            146405..146701
                     /locus_tag="PC465_000144"
     CDS             146405..146701
                     /locus_tag="PC465_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDF2647481.1"
                     /translation="MCNKRSCKKGGFLLLGAILGFIFGMFFAPKKGSELRKETKEKFN
                     DVKENPKEVLHETFNDVKERIINLVDDDNNEEDIKISEEDIVISKSFDDEGDVN"
     gene            146701..146961
                     /locus_tag="PC465_000145"
     CDS             146701..146961
                     /locus_tag="PC465_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HDF2647482.1"
                     /translation="MNAWGWQIGAVLVGSSALIVAIYLAKTLNSINKVVEKAYKIVDY
                     NERHIQDIVENASSISKGIDDIVYVINKILSIGNIFKIIKRK"
     gene            146973..147290
                     /locus_tag="PC465_000146"
     CDS             146973..147290
                     /locus_tag="PC465_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HDF2647483.1"
                     /translation="MSMNIDSNLDSQNKFWNVCLDGELDVSTADKLKEHLHALIEKNM
                     LDVKINLKDLDYIDSTGLGAMIGVLKKLKINEKEIYIVNPKSNVRKIFTITGLDKIFK
                     VEG"
     gene            147315..147701
                     /locus_tag="PC465_000147"
     CDS             147315..147701
                     /locus_tag="PC465_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2647484.1"
                     /translation="MEITTNPDYVSIIRLTASGIANKMGFPIDDIEDIKVAVSEACTN
                     AIKHSKDDVFYIVFNILDNAINIEIQDNGKGYDVSSISTPDLENPKESGLGLFIIKTL
                     MDDVDIESEHNQGTKIKMTKYLGVDI"
     gene            147701..148474
                     /locus_tag="PC465_000148"
     CDS             147701..148474
                     /locus_tag="PC465_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="HDF2647485.1"
                     /translation="MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARL
                     LAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKV
                     WTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQ
                     PMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRF
                     FFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL"
BASE COUNT        48235 a        25937 c        16855 g        57567 t
ORIGIN      
        1 cttaaaaata attcgtcaat actttttttg ttttttattt taaaaaaggt tataactttt
       61 ggtttttttt aataaatata attaaaacta atagatataa cccttgatat tacaaacaat
      121 gcatgcatat ataattttac ctattttgca attttatttt cataagaata tgaattagct
      181 ctcactctat ctacccaaac atttatactc ttaactttat taacattagt tgtaccctca
      241 aaaatatcca ttgcatcctt acaaaaatat atcataacat caagaaccaa aaatccaaca
      301 caaaataaac ataaaaaatt aattacttga aacatcagac attcccccaa taatttttta
      361 tatatagtat tctcataaat tattcttttt accttctcat aaattattct aaatattttc
      421 ataataaatt actttcaatc atattttcta aatataaagt ctcaatcaac aaaaactaat
      481 atcaatttct aacgtttgtt ggtaatttat aaattaaata tctaaaagaa tctttgaagc
      541 atataaaaag cattctacac tgacatttta aataaaattt agctatttat tgataattta
      601 atagctaaac tttatttaaa acttagtaga atgctaatat ttcttagttt tcttcttctt
      661 tatttggatt gttatcaata ggtttcatag tcgggaataa taatacatct cttatagatg
      721 gagagttagt taataacata attactctat ctatacctat tcctagtcct cctgtaggag
      781 gtagacctac ctctaatgct tttaagaaat cttcatccat ttcaaaagct tcatcatcac
      841 ctaattctct ttttcttaat tggtctataa atcttccttt ttggtcaata gggtcattaa
      901 gttcagaaaa tgcattagct aactcccact tattagcaaa tgcctcaaat ctatcagttc
      961 ttcttgggtc ttcaacattt ctcttagata atggagatac ttcaactgga tgatgagtta
     1021 taaatgttgg ttggattaat ttatcttctc caaattcttc aaagaaagca tttattactt
     1081 cccctcttct cattccaggt tttatctcta tacctttttc cctagcaact tctagtgcct
     1141 cttcatctgt atttatagta gaaaaatcta caccagaata ttctttaaca caatcttcca
     1201 tactcattct tttccaaggt ggtgtaaagt ttatttctgt tccttgatag ttaactatca
     1261 tacttcctgt agcaacttca gccatatgtg caataacatt ttctgttatt tccatcatat
     1321 cagtatagtc tgcatatgct tgatataatt ctattgcagt atattcagga ttatgtttta
     1381 aatccatacc ttcatttcta aacattcttc ccatttcata aactttatca aatccaccaa
     1441 caataagtct ttttaaatac aattcattcg ctattcttaa atacattggt atatgtaaag
     1501 tattatgatt agttataaat ggtctagcat ttgccccacc tgctatagta tttaatattg
     1561 gagtctcaac ttctaaaaat cctctatcat ctaagtatgc tcttaatgct tttaatgctt
     1621 ttgttctaat taaaaaagca ttttttactt ctggatttac tattaagtca acatatcttt
     1681 gtctatatct tagttcttgg tcttttaatc catgatattt ttctggtaaa acttgtaaag
     1741 atttacatag taatactaca gatttagcct ttacagatat ttcacctttt ttagttttaa
     1801 agatttctcc ttcaattcca actatatctc caatatcata tgttgaaaat acactatatt
     1861 cttcctctcc tatagcatct agtcttacat aagattggat tcttccctct tggtcttgaa
     1921 tatctataaa gccagctttt ccttgtattc tcttgctcat tatacgtcct gctatttttg
     1981 tagttttacc ttcaagagaa tcaaagttat cttttatatc catagaataa tgagttctat
     2041 catatctact ttctttaaaa ggatctctac ctgactcttg taattttttt agtttatctc
     2101 ttcttacttg aagtacttca ctaaggtctt cttgaatttg cgcttcttca ttgctttgtt
     2161 gattattttt catttttttc ctccaaatta tcttcttatt tctaatattt caaacttagc
     2221 aactccatca ggaacttgca cttccacaac ttctttcgca gctctaccta aaagtgcttt
     2281 ccctacagga gattcgtttg atattttacc atcatatggg tctgcttctg tcgaaccaac
     2341 tatagtatat tcaacctctt catcaaattc taaatcctta actttaacta ttgatcctat
     2401 tgtaacaaca ttaaggtcta ttttgctttc atctatgata acagcttttc taaccatatt
     2461 ttctaatttt aaaattcttt cttcaacttg tgcttgttcc tttttagctt catcatactc
     2521 agcattttca gataaatcac caaaagatat agcaactttt attctctctg caacttcttt
     2581 tctctttaca acctttaagt tttctaattc ttcttctaat ttatcatatc cctcttgtgt
     2641 caataaaaac tctttatttt cttccattat aaatacaact ccttcacaaa tttcttagga
     2701 attttcctaa ttatatttta aaaattttat aatctttttt taatttatgc gctatattat
     2761 aagtcactat tatttttatg tcaaggagtc ttccatatag tactccaatt tcgacacaac
     2821 ttcttgatag tcttctattt tgttaatttc atcccttaat tttgcagagt ttctaagtcc
     2881 ttttaaatac caagcgatgt gttttctcat ttcccttaca gctacatact ctccatgttc
     2941 ttctactgca agttttaaat gcttaatggc agtacttatt ttttcgttaa gagttggctc
     3001 tggcaaaatc tcgcctgtat tcatataatg gtttattctt ttaaatatcc aagggttacc
     3061 ttgagcaccc ctacctatca ttatagcatc acaaccagtt ttgtctaaca tatttattga
     3121 atcttctatt gtaaatacat caccatttcc tataacaggt atactcaaat ttttcttaat
     3181 ctctgcaatt atatcccagt ctgctttgcc tgtataaaac tgttctctag ttcttccatg
     3241 tattgctaaa gcacttattc cacaatcctc tgctatcttt gctatttcaa cagcatttac
     3301 actattatca tcccagcctt ttcgaatctt taaagtcact ggcttttttg agttcttcac
     3361 tactgccctc aatacctctt ctgcaagctt aggatttttc ataagtgctg agccatctcc
     3421 atttttaact acttttggag ctggacaccc catatttata tcgagaatct catttgaata
     3481 atcattcatt atctctgctg ctcttcccat aaactctggt tctgaaccga atatctgaac
     3541 tgctacagga tgttcttcct cttctatctt aagcattttt ttagtatttt catcatcata
     3601 gcaaagtgcc ttaccattta tcatttctgt atataaaagc ccacatccct gttctttaca
     3661 aattaatcta aatggaaggt ctgttacacc tgccataggt gatagaaaaa ctttattttt
     3721 caattctaaa tttcctattt tcattgtttt tctcctattt ttgcctttat tttgtgattt
     3781 aactttaaat tcttatttcc tcattataat ataccacata tagctagaaa tctatcataa
     3841 aaagggaatt ggatatataa cccaattccc tgtatattaa ttattcttgg tttttttcat
     3901 atattattct caatccttct agtgttaaaa aaccatctac ataatctata cttttcgtct
     3961 ctgaagcaat cagtttagct aatccacctg tagctataac cttaacatca tcacaattca
     4021 attctttctt catcatactt attattttgt caactaaacc aacatatcca taaattattc
     4081 cagattgcat ggctgataca gtactcttac aaatagtcat acctggctta gctaattcta
     4141 ctctaggtaa tttagacgca ctttgaaata acgcctcact agatattttt attcctggtg
     4201 ctattgttcc acccaaatat tcaccttttt cagagatagc acaaaatgta gttgctgttc
     4261 caaaatcaac aagtatactt ggtgctccat acttttctat ccctgctaca gcattaacta
     4321 ttctatctgc cccaacttgt tttggattat catattttat atttagacct gtttttatgc
     4381 ctggacctac tattaatggc tgttttttac agtactttat acaaaagttt tcaagagaat
     4441 gcataacatt cggaactaca gatgatatta taacatcatc aatatcactt atattcacat
     4501 tatcataatc aaataggtta cttatcagga ttccatattc atcagacgtt ttttccctat
     4561 ctgttttaat tctccagtaa ttaactaatt tgtcaccttt atatatacct aaaaccatat
     4621 tagtatttcc aacatcaaat actagaagca tatgtcatta accttctttc tattttttgc
     4681 ttttcttaag tacagtggca acagcagcta ctactaaagc ccctactatt gcttctggca
     4741 ccccatttgc tgcggcaaga gccattatta cttttcctgc tgaaccactt ttacccattg
     4801 catgaagata cttgtcagca tataagacat atatcattcc taaaactcca gctgtattta
     4861 acagagaacc tattgcccct gtaattaaac ctgatatgta taccttattt gtagccttaa
     4921 ttattaactg atatacataa taagctaata cacctatcat aactcttggt aatattgaaa
     4981 ctaatggatt tataaaaaca aaagatgtta ctgttgggtt tgttatagca tttaagagac
     5041 ttgatatccc aaatataaat cctattgctg ccccaactat tggtccttcc ataatagctc
     5101 caataataac tggtatgtgc attatagttg cttttgtagg tccaactgga ataaatccca
     5161 atggagtcat agatagcata atagaaatag ctgatagtac tcctattata gtcatctttc
     5221 ttacatttac ttttcttact gatgcacttg tgttcatcat aaaaaataca cctccgttcc
     5281 agctcattaa gatgccggac tacttaattt tttaattttt tcgttttttt cttataatta
     5341 tgagtcaagc taccattgta ggatgcccgc tctaacaaga ataattttat caagatgagt
     5401 tgccattgtc aacaatttga caagaaaaat atgctaattt catcatattt ctcgtttttt
     5461 tactatatct ttatatgcca ttatattttc tacactatcc gcttttttta ctgcatttat
     5521 tatacttttt tccacaacct ctacagccaa tgaacctact aatgttatat ctgcttctat
     5581 ttctcctgtt gatattgtga atattgtatc tccatcatga ggtgtatgga taggaaaaat
     5641 agacttagca tatccatcat gtcccatttg agatatcttt ttacatccag ctttggttaa
     5701 cttagcattt gttgcaatta tcccaattgt agtattatct acactaaatc cacctttact
     5761 ttcaccttgt ttcattaatt tatatgtatc aattgtttct gtccttttat catttaaagc
     5821 accagctata accttaccat tttcataaac atctccaaga gcatttacag caattaatgc
     5881 agatacaact agaccattat ctaattttat agaatagcta cctattccgc ctttcatagc
     5941 atattcctga cctcttatct ttccaacagt ggctccacaa cctgctccat aatttccttg
     6001 atttaaaata tcagtatttg caacttcaca agctctataa cccatcttta aatctggtct
     6061 acatttaaag ctccctactc ctaaatcaaa taaaactgct cctacaacta taggcacttt
     6121 acctacacct acatcaaagc caattccttt ttcttctaag tatctactta caccacaagt
     6181 ggattcaaga ccatatgcag aacctccagc caaaactact gcatgaactt tttgaaccat
     6241 atttacaggg tctaataaat cggtttctct agtccctgga gcagagcccc ttacatcaac
     6301 accgcaagta gctccttctt cacatattac tactgtgcac ccagtaagac catttctatc
     6361 ctcaacctgc ccaaccttta agccttctat atccaaaata ttattataca tatccttttt
     6421 ctcctcttat agaaacttca cctgaaataa tttcttttat acttccatca cttctttgaa
     6481 ctaataaatt tccctcttca tttatgtcta aacatttcac tagttctcta ttatctcctt
     6541 ttaatacata tatattttta tctataattg cagaataatc tctacatatt tttaaggttt
     6601 tttctttgga attatttaca gtataatcta aatataattt ttcaaattca gtcaatacat
     6661 tcctaacaat atctactctg gataacatat acccttcttt atacaatgat gtggctttgt
     6721 cagctatttc ttgttcaaaa tccattattt taacatttat tccaattcca agaacaacat
     6781 aatttgttct ttcaatttca gcagataact ctgttaatat accacatatt ttttttccat
     6841 ttaaaataac atcatttggc cattttatta atgtatttgc tcctagattg tttaaagctt
     6901 tcgttacact tgctcctgct attaaagtta taaatggagc tttgaatggt tccatatttg
     6961 gttttaatat aatactcatc cagattcctt catgaggttt tgaatcccat cttcttccca
     7021 atcgtccttt ccccatgtct tgatgttcac ttaaaatcac agtcccatct acactattta
     7081 tagctatcct tttagcatgt tcatttgttg aatctatagt gtcaagatgt tcaatatttt
     7141 ttccaataaa ctctgtatct aatttatagt aaatattctg tgggcttaat aaatcagttg
     7201 gattttccgc taatcgatac ccttttttat ttacagattc tatattatat ccctcttctt
     7261 ttaaggcttt catatgtttc catatagctg cacgtgacac ccctaattgt tttgataatt
     7321 cttctcctga aataaattca gatttattat ttaatataat ctctattatt ttatctcgca
     7381 tatttcacct ctaatatgac ataatttcat gacttatttt cttctaataa ataattatac
     7441 attattaata tacttttaat actattaatt ttaaatttcc tttttaatta ttataatggt
     7501 tgttttatat tttatattga tgatttatat aattttacat tttatttaaa taattttaaa
     7561 ataataaaaa aactgaaagt atcaattaaa ttaatacatg caaatataat ttgcttatta
     7621 atttaatatt atactttcag ttttagtatt taatccacat cagataataa tcttaaaatg
     7681 accaaggtct taaaactatt tatctttatc agatttatct tctaaatttt tatttatatc
     7741 aataacattg tttctttctt cttcatcttt ttctaatttt atagttaatt gttcttcaac
     7801 ttctttagaa gaattttcct ctgtaactgc attttcaatt tcattcagag gtaactcttt
     7861 attaaatgct tttacaaatt gttctgcatc taaagtttca tatataagta aagcttgtgc
     7921 tacatactct aatctatcca tattttcttg taatatactt cttgtcttat catatgcacc
     7981 atcaactata cgctttgttt cttggtctat ctcaaaagca acttcttcag aataatttct
     8041 cttacttgaa aaactattac ctaggaatac ttcatcatca ctgtcaaatg acattggacc
     8101 aagcttagaa ctcattccat actttgttac catacttctt gcagtagctg taactctttc
     8161 taagtcattt gaagcacctg tagatacatc cttaagtact agctcttctg ctactctacc
     8221 accaagtaaa actacaatat tttctttcat ttcatttttt gtagcataga acttatcttc
     8281 aacaggaagt tgcattgtaa accctccagc tcttcctctt ggaactattg taacttgatg
     8341 aacaggactt acttcttcaa gtacatgggc acaaactgca tgccctcctt catggtatgc
     8401 tgtaagtctt ctttctttct cacttattac tttcgatttt ttagccacac ctgctataac
     8461 ctttgttata gcttcttcta tagtttccat cttaattttc ttttctcttt ttctagctgt
     8521 taatattgca gcctcattca ttaagttctc tatatcagca ggagtaaatc ctggtgttct
     8581 tctagccaag acatccattt ttacatcatc acttaatggt ttatttcttg agtgaacttt
     8641 aaatatagcc tctctacctt ttacatctgg tgtaccaaca acaacttgtc tgtcaaatct
     8701 tcctggtcta agtaaagctg ggtcaagtat atctggtcta tttgtagctg ccatgattat
     8761 tataccttga tttaccccaa atccatccat ttcaactaga agttgattaa gagtttgctc
     8821 tctttcatca tgacctccac caagacctgc acctcttttt ctaccaactg catcaatttc
     8881 atctatgaat atgatagctg gagcactttt cttagcctgt tcaaataaat ctcttactct
     8941 tgaagcacca accccaacaa acatctcaac gaaatcagaa ccacttatac tgaaaaaggg
     9001 aactcctgct tctcctgcaa ctgctcttga tagatatgtt ttaccagttc caggaggtcc
     9061 taccataagc attccttttg gtattcttgc acccaattca atatatttct taggattctt
     9121 taagaaatct actacctcct gcaaatcttc tttttcctca tctagtccag ctacatcttt
     9181 aaatgtaact ctagtttttt catcatcttt atgaacctta gcttttgatt tgccaaaact
     9241 cataaccttt ccgcctccac cttgagactg attcataaac acgaaccaaa taatcaccat
     9301 gaagaatatt aacagtaatg taggcaacat ttcgacaaac caaggtgtag atggcttagc
     9361 ttcaccacca aaagttagtt tcccagcctt agcttggtct aacacctcat ctgcaagttt
     9421 atttcccatc acttctgttg gaacatatga cttaaacttt gtatttgtat cttttatagt
     9481 accttctaca gaagtttgat ttacaaagta taatcttgat atattctcat ctgttaattc
     9541 tctatatact tcagagaatt ttaaatcttt tattttttct gtaggcttac ctgagaattg
     9601 aactatacct actataatta taaaaacaag tagataaaaa cctgcccctt ttagcaactt
     9661 attcaatata gaagccctcc tttcatacat tgctttgccc tataatttgt taaaattaat
     9721 ttttaatact tcttttgtgt tttcatcaat tttataattt tcactgattt tataatctcc
     9781 aacacatatt attccttcac tatctgtgat tataggaatt ttacatcttt cttctcttgg
     9841 gatttttaaa tctatgaata aatctttcac ttttttactt cccatagcaa gctttatctt
     9901 atcaccttgc cttctgcttc ttattactat accccctttt accttattaa aatcaaaccc
     9961 tttagatgaa ttgtctaatt tcatactctt atacctatct atgctcatta cttgggtctc
    10021 aataatttgt tttaattctt ttattttaat aaacccatta ctaggtacat tgtaataaaa
    10081 ttcaatttcc tcattaacaa tttcctcatt cgttaatatt atacagtctt tttttctata
    10141 aacaaatata tttcttggaa gagttaacat tttatttact tttgaattat cttctaaaga
    10201 cattatatcc tctatatgtc tttggtcaac aaaattagta tctcctagta tatgttttat
    10261 ggaatttcta agaactctaa ctttgatagc atcatgtaag caaacaaaat tgtctaaatt
    10321 tatctctaca aagccttttt cttttatatt cgaaacttct ctaaatttag cttctgcctc
    10381 tttctcaata taatcgttat cactttttaa actattgctc atcctcacta tagattctat
    10441 tacatttgaa ttaaaattat ccttcatata tggtaaaagg tctaacctta tcttatttct
    10501 agtgtatata ttttctaaat ttgttttatc tatcctcgga tttaaattat aagcttcaca
    10561 atactcctct atctcatttc tttccacgtc taatatgggt ctaattatgc aattatctct
    10621 aatataatca attcccttta aaccttttaa acctgttcct ctcatgatac gcatcataac
    10681 cgtttcggct tggtcattga gattatgacc tattgctatt ttattggctt taatcttatc
    10741 cttaatttca taaaacattt catatcttag cttccttgct ccttcttcta atgataatcc
    10801 ctcattttca caatattttg gtacattaat agactttaca aagaatataa ttcccatatc
    10861 ctcacaaagt ttagatacat ataatgcatc tttttgagct tctatccctc ttatttgatg
    10921 gtttaaatgt gctgcatata tttctatatt aaaatctttt tttaatctat ttagtacatg
    10981 caataaacaa actgaatcag gtcctccaga aagacctaaa actattttat cgcctttttg
    11041 tattaaatta tgtttattta tagtacttag taccttatca aatatcatat ttatccctct
    11101 tacacttagt tttattcact tttaagtata ctttctataa aaaaacgcta aacccttgta
    11161 tcaattttaa gaaattaaag tttaatataa atataataat accaaataaa ttaaataaaa
    11221 ggtagttttt tcactacctt tataaaattt ctggaaaata gccatagtta ttatttagta
    11281 cctatgtata tatctatttt attcctacct aaaaataaat cttgtacctt tatattatag
    11341 tctattttca attttatgtg ttccccttct tgtatattta tatctaattc tcttgtatca
    11401 atatcaatta ataaagtacc ttgtggggtc acatactttg tagtactact ttctccacat
    11461 ttaaacagca ttgttgagtt aatagcacca aactttttga tactaacttg atttttaagt
    11521 atctttatag tattagttat ttctatattt tcttcttttt ccttgtaaat aacatatatt
    11581 ccatcatttt tataaaaaat tttaccaaag gcagtcatct ctatggtgtc catatttcct
    11641 ttttcatcat attgtctagt atttatactt atttttacac tcaacgattt ttcctccata
    11701 gattcttcat ataaactagt atttttgtat ttctactttt tgaatcttat caattttttt
    11761 ctttaagaac tctcttgcta tatctgaaaa tttttcaggt atatctgata cataatattg
    11821 ataagttcca tgaatttctg tattgtttat aatattttgc acctctaaaa tcttttttaa
    11881 atcctttgca gtctctttag ctggattaac aagttttata tgctctccaa cttcttcacc
    11941 tattgttctc tttaaaatag gataatgagt acatcctaac actaaagaat ctatattttt
    12001 ttctttcaat tcttgtaaat atatctttgc tgtcaattta gccacttctg tatttgccca
    12061 tccttcttca acaataggta caaataaagg acatgcttta ttaacaattt ctatactctc
    12121 atctatttta gatatttcca agttgtatgc ttttgaactt atagttcctt cagttcctat
    12181 tattcctaca attttgtttt ttgtagaact tacagctgtt ctagctcctg cttctataac
    12241 tccaattatc ggtatatcat atttttcttg agcttctttt aagcttcttg cagtagcagt
    12301 gttacatgct ataactatag cttttacacc ttttgttttt aaaaagttta tagcttgaaa
    12361 agtatattta attatagttt ctttggatct tgaaccatat ggtattctgg cagtatctcc
    12421 aaagtatatt atatcctcat ttggtaatat cttcattatc tcttttagaa ctgttaatcc
    12481 acctaatccc gaatcaaaaa ctcctattgg tttattgttc atctttatac aacacctact
    12541 ttacattttt gtgtttaaca acaacttatt tatcgctaaa atttatattt atattcataa
    12601 ttaatatatt attacctaaa tgattattat agtttatttt acacaaaaaa taaaggagct
    12661 atcttaaatt agaaaataat ttctacaaaa agacaactcc tttcactact taaaaattta
    12721 aatttatttt gcaaacacat gatttcctat tctcatataa ggattcaatc tatttatcca
    12781 tttgcaagtg gctatttctg gattccaaaa atatactgct ttattagttg ggtcagttcc
    12841 ataaagagct tcctgagctg ctttacgtgc tgagtctgtt ggtgccatct ttattgaacc
    12901 atcaagcaca actgagaaag catttttttg atatatgact tcttctattg tgtctggaaa
    12961 tctagggtcc aatactctat ttattactac agctgctaca gcaacctgtc cctcatagct
    13021 ttctcctcta gcttctcctg caaccaactt agataataac atcaaatcat tatcagataa
    13081 atttattact tctttctttg ctatattttt ttcttgtttg tttactttct taatattttc
    13141 tgttggttca tatgcaaata cctctttaat aggcataaat ataaaagtca aagctaatag
    13201 tgtagccatc agtttactcc acctgtccat gattaaaacc actccttaca ttcttatttt
    13261 taaaattttt tctctaaatc cttgactact tcaagtactt taaacttaat ttttactcta
    13321 cttgtttttt ttggtgtatc ttgttttatt aacttatatt ctttatcagt taaaacttcc
    13381 ttcaacttat catctgtaga tttatctatc actccattag attcatcaac aaaacatagt
    13441 ggagggaaca taacacacca ccagtttttt ccttcacctt tcccaatgat aatctttaat
    13501 gctttatatt caccagctgg aagaactata ttagaatatt gtttagtagg gaaattgcta
    13561 tattgtatac ctacctttac actgtaatta tatccatttt taagaataat atttttactt
    13621 atttcttcca gactactata ttcctttttt ataatagctt cactttcttt tatacttttt
    13681 gaattttgaa gctttggctg taaatatttt attacttcat ctctaacttt tagtttaagt
    13741 tcttggtctt catctgtatt gctgtttgct ataacatgaa atcttattaa tttatcttta
    13801 taatcttttg atatattgtc tacttttttt acctcaccat ttattactat tgtcattatt
    13861 gatatgactg atataagact taatattaat agtcccaatc taatcttaat ttttctcatt
    13921 gaaaattccc cctcaagata aatttatatc atcaattatg tccaattaaa tttaatttat
    13981 tcataatatt ttttaatact aataaaaaaa gctatcttaa aatgattaca atcattttaa
    14041 aatagctttt taaaccttat attttataag tctttactaa tcatagcctt atctatcata
    14101 aactgctctg ctttttctat atgctctgta gcatacttct tggatagctc actatcacct
    14161 ttaattatag catcaagtaa atatttatgc tcttcaacaa tattatgtga tgtatcataa
    14221 gcagacatat aggtaactct aaatctatat acttgttccc acaatgagtt tattaattgg
    14281 attaattttt tattattagt tgctttaaat atacattcat gaaattctac atcaagtttt
    14341 aataacgcat ctacatcgga ttccaaagtg ctttttttaa attcttctga tatatcttta
    14401 agctttttaa tatcttcatc actaattctt tcagcggcaa gatatgctgc taagccttct
    14461 aggcttgctc ttacttctaa tacatccata atatccttta atgacatatt tgccacatac
    14521 gcaccttttc taggcaacat aacgactaaa ccttctaatt caagctttct tattgcctct
    14581 ctcactggag tcctacttac tcctaattgt tctgctagtt gcacttccat tagcctttga
    14641 ccaggcttta attttccttc taagattgct tctcttaaat tctcaaagac tacatctctt
    14701 aatggcttgt aattatccaa gttcagttta gttaaattct ccacaaattt caaccccttt
    14761 ttgactgcta ttaacaacat acacctgttt atattttttt aataattctt tttttccaat
    14821 tagagcatct tctttatttt taaatagtcc aaaaactgta ggaccacttc cactcatcat
    14881 agaacctaaa gcattatttt tcatcattac ttgttttata tcacttattt ctttgtgttt
    14941 acctatagta acattttcaa gaatatttac catgctttct gatacagctt ttatatcttc
    15001 agattttaaa cactctatca aatatttatt atttggtctt tttttaatat tattcaaatc
    15061 taatccttga taaacttctt tagtagaaac gaataagtct ggtttgcata tcaatatatt
    15121 tgtatcacat ggtaaacctt tgatgtttgt tagcttttct ccaatacctt gagctaaagc
    15181 aggtcttcct gatatacaaa aaggaacatc tgcgcccaaa ttaagtccta tttcttttaa
    15241 ttcatcttca gataatctaa gttcccatag gtgatttaaa cctactaata ctgcggctgc
    15301 attagaactt cctccagcca tccctgctgc tacaggaata tttttttcta tgaatatttc
    15361 tacacctttt tttatataaa atttattttt aagtattttg gcagctttat aaacaatatt
    15421 atcttcatct aaaggaatat ctaaactagt gctttttacc tttatttcat cttcgtctaa
    15481 ttcttttatc tttactatat cgtataaatc tatcgtttgc attatcattt caacaaaatg
    15541 ataaccgtct tgcctttttc ccaagacatc aatggataaa tttatttttg ctctactctt
    15601 tagtcttata aaatccattc tatcctcctt gtttaaagaa taatgcatca ctaacaataa
    15661 tattatacta caaaaaataa aataataggg tattataata ccctattata cttaattact
    15721 ttaaattttt taatattaat ctactaatac gacttttttt tctaaaataa gacacttacc
    15781 aggcttaatt ggttcatcaa gttttatatc attaagttct gcaatttcat tttctgttgt
    15841 attgtatttt tttgctatat tccagaaagt atctccttct ttgcatatat atacgattat
    15901 gctaggagct ttagataaat catatacacc ttggtcttct cccttgataa taaaattttc
    15961 tgctttctta tctaatgctt cagtaaatct cttaattttg ataatcaggt ctatctggtc
    16021 cctattcaaa tcaacttcga ctttatcaat acatgctgta ttaaacacag atgctgtatc
    16081 agttagatta tccatttcta tatcatgttc aaatggaatt tcctcactaa ttttataaac
    16141 caattttaaa ccttcaactg ggacaaataa aatttcaact tttatgattc cttgtataat
    16201 gcttttattt ccttcaatat aactattttc tatagacatg gttggacaaa cgcttacaat
    16261 atcttttatt tgtatatcat cattatcatt tcttatgcct tctctaacca taaatgtttc
    16321 ttcactacgt cttaaagtct tatttaattg aataggtttg tggtcaaatt ttattatctt
    16381 ttgaggcgaa tatgcatctt gtaatacttc tcttgtaact tcatctgtaa cttttacctt
    16441 acaacaagcc atacaatcta tttctaaaag acctgtgttg ctttcactat tttgcttgaa
    16501 aatatgatta aaatctgaca tagacaacaa tacttcttca gtcataccat cactaactcc
    16561 agggacttct acaaattgag taaactcaat acctactcta tccaactcta caagttcacc
    16621 ctcatatgta caagctaacg gatttatttc taatactcca ccaataataa ctttattgtc
    16681 agtcactcta ctttctttta ctttaacaca tggatttaaa cttattatag attgaatttc
    16741 ctctgtgttt attgttatag tatctcttat agaactttct gctttttcta ttccaactat
    16801 atcttgaaaa caaatttcct ttctgtgctt ttgtatgcct tccacttgcg ccacatcttt
    16861 tacaatgtct aacctttgct tttcaaacaa acttcccctt atattcataa gagctcctac
    16921 tttaatcttt ctctcattca ttatagtaca atccatatgc tctacttctg aaaataacat
    16981 gtattccata tcttgaataa cattgtcttt ttctattact tcgtttatat ctacttttcc
    17041 gtctacatta gaaatagtat ttttatcatc tgcaatatag attacattat aattaaaact
    17101 acctctgcaa agtatcttcc catctgccat ttcaattttt ttaagtgata tgtatccttc
    17161 tgtttttaca atttcatata catctaattt tttgtctggt acaactgcct ccgcttcaat
    17221 gaatgtttga aattttccaa agtctattct attgtcaact ttaattacat ctttaattaa
    17281 ttccatagtc tacctcctta agtattataa aaatatcaca ctatatttat atttaaggag
    17341 caaaaaaaaa attacaccta tttttaaata ggtataattt taacttattt gtaatttatc
    17401 ttgatctcta aaaacttgca actttacatt agatgttaat aaatctgagt aactataaga
    17461 tactctagga tatccattac tttcatcatc taactttata acaaacacgc ttggataaac
    17521 tttttctagt ataccctctt ttgtaataat ctgctttctt cctttattag ctttcaacaa
    17581 tattttcttt cctatatgtc tctctaagct tactcttatc ttatctagag tttgaacagt
    17641 agccacaata tcaccttctt taacgtttat atgtttacat aatatcacat ataaacattt
    17701 ttgtcaaatg tttaaactaa ttattttata tattttttgc aaaaatgtca atactatttt
    17761 tgaagatata cagtataatt atgttaattt ttgctaatgt aatattgttt ttggcattgc
    17821 ccatctaaat tttcctcttg tttcagaacc accaattccc ttaacacctg taatagtctg
    17881 ctctataacc tcatcaatag gaactactac atcaattctt gaacaagcaa ttttctccac
    17941 tataaaaaca gggtctaatg catgtatcat tattcttcca ggcgaacttg catagtttgc
    18001 tcctgcactt attatttttt cataatttga ttggcatgct cctgcgaata ttacaagatt
    18061 atccaaattt ggttgccatt tacgtgcttc ttttactgtt ttaacaaaat ttgaagagtt
    18121 tctatagtta ctcatatctt ctatatctcc tctttttatt gtcattgcat catgacctgt
    18181 tattactagt atatccggat tatatttttc tagtagtgct cttacttctt tatactgatt
    18241 ttgctctgaa acagctacac ctactgcagg tattccaagt tgagcatata catccaagca
    18301 aatttttaaa tattctttat ctccatctat ctgtagtact tttccaggca ttccatatgt
    18361 gttaggattt aattgaagtt ttggaactgc tctagtcatt cttttttgtc tttctttagc
    18421 ttttcttact gacttatata ataaattttc tacattttta tctattaata tatcttttat
    18481 atcaggtgct tttactaatt ctaggtcatc aatataagca tctgctatta ctctaaatgc
    18541 aattcccttt agtatagcta ttttctcatt attttcatct acaccaaaag agactatttt
    18601 aaatactata tctttgttat gtgactttct agctacaatg tctcctacct tcatagttaa
    18661 acctccaata aatttttatc ttagtttata ctatgttcga tataaaactt tgtttcctaa
    18721 tgtcaaaaaa acatttctta taatacttct tttatcactc ttaaagcatt tttatagtat
    18781 atcttttcta tatcatcttc actaaaccct tcttttttta gaggttcata cagtttaccc
    18841 atctgagata tatcttcaat ctcaactttt gaatctattc catcaaaatc tgaccctaga
    18901 gatacaacat ctattcctcc aacatttaca atatgtttta tgtgtctaac catatcttca
    18961 agtttacttt cacttttatc acttaaaaat aagtggaaga agtttatacc tgtaactcca
    19021 cctttatttg ctaatacttt aatcatatca tcagttaaat ttctagaatg attcatcatt
    19081 gctcttgaat tagaatgtgt agcaattatt ggtttagaag aaatctttgc aatttcataa
    19141 aatccaccat ctgaaatatg agaaacatca accaacattc ccaattcatt catcttatgt
    19201 accacttctc ttccaaaatc agtaagccct ttttctctat attctacttt attatgagga
    19261 aagctcaatt cattcacatg attccaactt attgtcatca ttctaacccc taagtcgtaa
    19321 aatttcttta aattttctaa tttaccttca agtactgcac cttcctcaat agataaaaga
    19381 gctgtaagtt taccttctga ttggtttttc ataatttctt catagttagt agctaaagct
    19441 atttcatcac tatttttttt catttcctca tgaaatttat ttgccatact catgcaataa
    19501 tcaaaaggat gttttacttc ttcagtatca acaaaaagag caaatgtttg agctaatgaa
    19561 tccccctttt tcaatctgtc tatatcaaca gaatatttat tagacttaag ttcacttgtt
    19621 tctacatttt ccattaattt tgctatagta tcacaatgta aatcaagaaa tttcatattt
    19681 ataccccctg tatattttat atttatatct aaaaatagaa atagttgtcc ttatagacaa
    19741 ctattgacaa ctatttttta atattctttt taatattact taatcttatt cttcttttaa
    19801 gttaggtatt acttttttaa cttcttcaat ttgatgccat gttttatcta tattattttc
    19861 actaatatat ttttttaaat cagttaaaga tgtaaaatct ttaactgata aattgtcatc
    19921 atcatctgca aatcttaaaa taaacatgag actcccttac tttccacaac atttcttata
    19981 tttttttccg cttccacatg ggcatgaatc atttcttcct atttttgctt ctttaactat
    20041 tgttttagac ttcttataag cctttattat ttcttttctt tggtctgctg gtagtatatc
    20101 ttcccaacct tgtaaattat atagccaatg agcctcaaca gttaccatat tgttatataa
    20161 tttttcccaa tctattttta tagaaacttc tttatcagct tctacttctt ctaaaactat
    20221 atcttctttt aagctttcac ttattccatc tatgaatccc atgaaaaatt cattagtagt
    20281 tccaaatttt tcagccaatt cacttacttt accttcaaca acatccattt tattatttaa
    20341 tatttcattg tatattccag cttcaacttt caaatattct tcccagaatt ttacttctgc
    20401 ttcttgactt tcatgattat cacttaaatt tctccattca gtatataaac tcatactttt
    20461 tcctcctaag tatacctata tttttatagt ttttatagta taaaatcttt tagttagatt
    20521 ggaagtttct tctttttgat tataccatat tctatttaaa gttaactctt atattatatc
    20581 ataattaaac aattctttta atacttttat agcatactct tggtttataa aataagggct
    20641 tgtcgcaatt gttattactt tggctttttt aattaagttt tttatcttgt aaaatttgag
    20701 ttcaaatggt atatagtcca tatcacttga aaatatatcc aaatctatat caagaacaaa
    20761 ctctgattct acttctaaat caaatccata tagactatct attattatta attctgaaaa
    20821 tatgttatat tttaaagcag gttttataaa acttcctaca tttaaaactt catttgtata
    20881 tctaaataca tcttttagat tatttacatc tacatcatag ttctcaggtt ctctagtatc
    20941 cttatgttgg tctacatgca ctaacttgca tccttttgta aactcaccct ttaacaaaga
    21001 ttttgcccaa aaataaaatg catggttatg attgtcaaac acatatatct ttttatttcc
    21061 caggacatat tcgaccatat tctccaatcc ttttgctttt atttccttat tttcatctac
    21121 ttcattaaat actacctcat tgcctaacct tacatcattt aatgtaccat ttattagttt
    21181 tggaacgtat atgctcttat tttctctttt atcatatgaa aatacattat ttcctactgg
    21241 tttttctata taaaatccac tatattcata attttccata aaactttatt tcctccattg
    21301 ttatataaat atataagtta taattttaaa aattaaaatg cacttattgt aaatcatatc
    21361 atctattata gaaaacatct tatataacta aatataatat cttctctcaa tatgtattat
    21421 acaataagtg caaaatatat ttatataaaa tatactacat tcctataaca aaaccatcag
    21481 cttcaattgg aaggtaacta actcttctat tcaactccac ctttccaaaa aatactaccc
    21541 aatatggtct aaaaatactt tcaattttaa ctatttcaat ctctgggatt cctcccataa
    21601 acctatgagt taatctcata gccattttat ttgcctttgc ttttactctt cgttcgtcct
    21661 tatcactata ctgcacaata ttacaatcca cattttttac aatttcatat gtaggaaaat
    21721 cttgtactat actaccagaa cctgtagaac cattcactaa aatttttaat tcatttatat
    21781 cattagaata tctcctattc ttgaaaatgg gtttcgtttt gtgaatttta agtgtgataa
    21841 ttttaaactc tatataatga agtctaactt catgagcata tttgttcttt aatattagct
    21901 tactaaataa agaatttttt ccacttttag ctatctctat agcttcttct tttgtaattc
    21961 ttataggtaa cgctcttata tccataaaat cattctcttt cttatttttt tcttgtcatt
    22021 tttaaaactc tatatatata atcaaaaaat attacaatta caactgacat aactccatat
    22081 ggaattattt ttccaactat aatatcattt ctagtcaata taccataaaa tataaatcct
    22141 gttattaaaa agtacaataa tactagaaaa ccgtctattc caagccattt tatttctaaa
    22201 tcttttttta ccttagacac taatttagac atagcagttt ctccttttat agattatttt
    22261 gtgtatttaa attttcacct attctattac caatcatcca tgcaataaat gaaaaaggta
    22321 tagctatcac aagaggctct aactcaaagc tctgaactgg aaatatttta aaataaccaa
    22381 aagtcactcc accaacaatc attcctaaaa taccacccat agatgttctt cttccatttc
    22441 caagaagccc acctactata ggtacaaatg ccgaacccat ccaaatactt cctacaaata
    22501 tacatgcatc atatacattt tcaaatctaa atgctacgct aagccccata actgctgcta
    22561 aacatacacc tattctagta aactttacta attgtttctg agataactct ttttttgtaa
    22621 ttcttccata tatatcattt gctaatgtag ccccagctgc tagataatag ctatccaatg
    22681 ttgatattat agaacctaaa attcctatta taaatattac tcttattcct tgtggtaatg
    22741 tatctaaaac taaagttata tatccagcag ctggagccat ttctggataa gtagctctta
    22801 ctataagtcc tgtcatagtt aacaccatgt caaaacatat ccatagtgaa aaacaggtta
    22861 ataaggctct tcttccaacc ttaggagaat ctgctgctga aaatctttga taaaaagttg
    22921 ggtctgaata agctccaaaa gaatatacaa ttaacatcaa tgctttcata gctgacatac
    22981 cttttgtagg gtgcataagc tgtggtgcat ctttgagtgc ttctgtaaga ccttgaaacc
    23041 ctcctatttg ttcaaattga cctggcataa ccatagttaa accaaatacc atacaaaaaa
    23101 acaataccat atctgtaatg gcaactccca taagcccacc aagtactgta agtacaacga
    23161 ctactcctac cattattaat cctattaatt ctttatctat tttccatgct acgttaccta
    23221 tagttcccat agcagttatt tctccaagtt gtgcacaata tataaacatc aaaattgccc
    23281 caattatagc aacatgcttg ccataaaaac tttccagtaa atcaggaact gttatattgg
    23341 ttcttatatg aatccttgga ccaacccaca atgctaaagg cattctccca atatgtgcag
    23401 ctattgacca aactgcccat gcagatattc catatatagc cgcatactct acactaccta
    23461 ctgtaccaac tcctccatac catgatgcaa ccaaagttcc tactattaag gaccatggta
    23521 aacttcgatt tcctaggtaa taactttcca tatcttttac atttctagaa aaataataac
    23581 ctattcctaa taatataaat gcaaatataa ctataatccc attttcccaa aatgttaaca
    23641 tatctaatct ccacattctt atattttaat ttttaacttt aatatctaaa tatgaacaac
    23701 tctacccatt tccataaaaa taggtagagt tatataataa ttataagtat ttaagtaatc
    23761 ttgttattaa gcaattttat tgtttaaacc tttattttct cttttattta ttttatttaa
    23821 agcataagta gcaaatatcc ctataactgc acatactaca gataaaataa atatatatgt
    23881 atatcctgtt tgtccatatt tatctaacca attacctgca atagtgtaat aaaacgcatc
    23941 tggagaaaat cctataaatg aagcaaatcc aactactgct cctgtagttt ctaaagatat
    24001 attagactct gaaacagatg caaagtatat acctctaaat ccaaataaaa ttacacttag
    24061 tattatcatg tttattacag ctatccatat aaatcctgta ctcttaggaa taaccaagta
    24121 agcagctgta cttactgtca ttaatataaa tcctacaaac attactctta tagatgaacc
    24181 aactttatct gttataacac cagcaactgg agatgctccc atttttataa cataagttct
    24241 tattattgat aaagcagaaa ctagagtcat tggcattaca taaacttctg ataagtatgg
    24301 acttaaataa gttaaacttg agaatactaa ataagttgaa aatattataa gaccaattaa
    24361 ccaagccttt ggcattgtaa ctacttttaa caatgactta atacttaatc cttcatctga
    24421 tgctccacta tcttttttct cttctactaa gaaaaataga agtataccac atattataga
    24481 tgctgcagaa tataaccata ctacatattt gaatcctact gttatttcag caaatttacc
    24541 aaagaaataa agacctataa aagaaattaa tgtacctgat acgcctgata acccttcata
    24601 aaaaccaaat attcttcctt gctctgactc acttccttgc attctaacaa ccttaacaga
    24661 ggctgagaag aaggttaata ttgtcgtaaa tccccataat acaaatatta aaagtatcat
    24721 actatatgat gggaatgtag agaaataaaa tccaagtatt cctgaagcaa ttaaagaaaa
    24781 agttattaat tttctaactg agaatctatc tgcaaaccat cctcctataa aataagatac
    24841 cattcctact aatccatata aactcaataa gttccctatt tgtgtatgac ttaatgctaa
    24901 agcttgttgc attgggtcat aaaatgatga tttcatatat ggtaaactat acatagctgt
    24961 tgttccaaat gccaatatga atattatcaa aaatctttta acattatttt tgctttccat
    25021 tgattctctc tccttaaaat tttattgttt ataatctcat tcatataatt ttattttaat
    25081 ttttctattg cttgtttaaa atcatttatt atatcatttg aagattctaa tcctacagct
    25141 attcttatta gattttcccc attcatttga actaatgtat gctcttcccc taagcttgtt
    25201 gctattgttg caagctctaa agaattcatt aatcttctac tagcttggtc tcttgtcaat
    25261 ccattgatac catccttaag tttaaatgaa actacacctc cacctaaacc attcatttga
    25321 gttttacaaa gctcatattg aggatgagat tttaatgctg gatactttac caattccaca
    25381 ttctcttctt cctctaaaaa ttctgctact gctaatccat tttcacaatg ctttttcatc
    25441 ctcatatcta acgttttcat accccttaaa atcatccatg cactcattgg tggtaaagat
    25501 gctcctgtaa aacaacataa acttggccat ctaactaaat ctattaattc ttttgaacct
    25561 gctactgctc cccctaaagt atccccatgt ccatttataa acttagtaag actatgtatt
    25621 actaaatctg cacctaaatc tattggtctt tgtacaattg gtgtcccaaa agtactatca
    25681 actatagcta agcttttatt ttcatgagca atttctgcta ttgtttttat atctactaag
    25741 tctaatgatg gatttaaagg actttctata taaactattt tagtatttgg tctcattgct
    25801 tcttttacat tttgtggatt tactgcatct acaaatgtaa cttcaactcc aaatttagat
    25861 aacaactcag acatgaataa tttagtgtgt gaaaatattc catctgaact aactatatgg
    25921 tcaccacttt ttaccaatgc taatatagta gaggttattg cccccatccc tgatgtacta
    25981 gatatggcac tttctgcatt ttcaagcata gccaacttag cttctaactc tgtaagagta
    26041 ggattacact ctcttgtata cacatatccc catgtcatac acaactcttc aaaatgctct
    26101 actgtctttg cagcaaatgt tgctgtttga catattggtg tagccaatgc acctgttgtt
    26161 gggtctgcac tatgtcccca atgtattatt tttgtctcta aattttgatt aatattgtta
    26221 ctcattttga tttcctccca ttttgactta tttatacaac gttttccctg ccaaatttca
    26281 tcaatttagc ttagtcttaa tacatttttt caagtatact tttttatttg ttataatttc
    26341 taaaaatatg acacttattt tgttttttta cagttctaat tataaactct atagtaacta
    26401 tagagtcaat atgtttttga tatttttttt acaatgttta aaatagtcaa tacaaaaata
    26461 ggtatatctt agaataacta aagtcatcct aagatatacc tatttttata tcacaatata
    26521 aataattaca tataagcatt agttttttta tcataaatag atttttcaag atttatcatt
    26581 ttttcataaa tatattatag ttaaatattt taatattacc taacatctac aataaaatat
    26641 actcttaaaa taaaattata taattaaaaa tactctataa aagctaaaaa gtttttctat
    26701 tcgctacatc taaaaataat tagatagagg tataaatgta tttagtttat ttatacctct
    26761 agtcttttat aaattatatc tctactaaat tgatttttta gcacgaataa gtgtgctctt
    26821 ggagatacca gtcatcttca caacctctct atatggctta gaatttaata accccaatgc
    26881 atattgtatc tgttgattgc tgtatttctt tggcctacca tctttaaagt cctttttctt
    26941 tttagcaaat tcttttccta attgagtacg ttctattatc atatttctct caagttctgc
    27001 aactgcaagt aatgtagtca aaaagaattt acccattgaa gtattttcta aaaggcctat
    27061 atttaaaata tgaacactta cttctttagc aaataaacct tctattagtt gtattccttc
    27121 tgatgtactt ctagctagtc tatccagctt agttgcaaca agtaagtctc ccttttttag
    27181 agatgatata attttttcaa atttaggcct gtttgtagta gtgcctgtat aagtttcctt
    27241 tattatttta gcatcattat atttattcaa aatttcttgc tgttgctgat acaaactgtt
    27301 gttgtctgtt tgattttttg tacttacacg gcaatatcca tatataataa tcatcacttc
    27361 ctaacataaa gattttgtac agaagttacc cagaagcttg tttttactta tctttatcca
    27421 ttttactaaa acgatttttg ggtgtcaata ctgttaactt ttgacaccat aataattcct
    27481 ttataatttg tttgactatg tcaaaaatta ccaatataat gaaattaatg agtttataca
    27541 aattggagga aataatatga atagtctgtt aaaagaagca atagatgaat taaaaaacat
    27601 ccattgcggg gaagtttttt tattaaaaga attgttcaaa ggctatgaat ggaacaggtt
    27661 ggagatgaat atcagattga aattaggaaa actttttttg tatgaagtgg taactaatcc
    27721 caatttaaat gtagaggtca tcaataaaaa ttctgcttat cagcaaatgt ataaaaaaaa
    27781 atagtgactt aaatgtatat aatagtataa tcttcttatt gattcaaaag ttaaaacttt
    27841 taatacaaaa caatcattct attttaacat ttatcaatat gtctaaattt atataattaa
    27901 cacatacgaa tagtattgtt taaatcacat tatttaagat agataaatct taaccctact
    27961 ccagcataaa tactaaaata gggcttagaa ttatctatat ttttatccca taaaatgctt
    28021 agctcttcct cttgattgaa catatatatc tggggaaata caatagaagc gtaaatttat
    28081 aaaatttcca aagtcagaaa acttcagttc aaacttaggt ataccaaaac tttcaggtgc
    28141 tatttcgtca acaccaaaat agattataat tccattatct gtaagataaa atgcttggtc
    28201 ttcaggtata actaactcaa cattagaata atacatttct ctattttcat ttatttgaga
    28261 tttaatgtaa tcagtaatta tattaatata atcaactcca tctctaaaaa tgtcattaag
    28321 taaaagttct tttccagttg tcaaatctat attgtaatta ttcaatgtat tgtatttagg
    28381 cccatagtta ttagcaaacc ccataaggtt taatatcata ctcagtacat aatttttatt
    28441 aaaagtaact gcgtaactgg tagataccca atagctttgt tttggaagtg aattttgagg
    28501 agctgcgtta ttatattctc gttcttcttc ctgtaagcca tttttaaaat tatttacagt
    28561 cattcttaca gcattgttta tgttatttaa aataactggg tttacatacg tggattgatt
    28621 tctaatattg tatataacag gatactttac atcatatgaa aaatacttac ttctttcaaa
    28681 atcttcatta aattgtacat ataatatatt atatgtacag gtatttgtag attgataatt
    28741 ttccattaaa atcctccccc ttttataaaa aaatcagata caatataata tgcttaaaac
    28801 agtaataatg ttaatggtaa atgtaaagaa tagaaagtat ctaaaacagc aaaaaatgac
    28861 taattttgtg gtataataca taggattgag agttatttta taggaggaaa aatatgttat
    28921 tattagcaga taaatggaaa gattatgaac ttatagatat gggaaatgga gaaaaattag
    28981 aacgttgggg aagttatgta cttagaagac cagacccaca ggttgtatgg ccaatggaat
    29041 ctgaatgggc tttatggaaa aaccctcatg gacattatca cagaagcaat aaaggtggag
    29101 gtcaatggga acacaaaaaa agatatccag aacaatggac tataaattat aaaaacttaa
    29161 agtttcacat taaaccaact ggctttaaac atactggatt attcccagag caagcagcta
    29221 actgggattg gatgatagag aaaataaaga aagctaacag acctataaaa gtgttgaatc
    29281 tttttgcata tacaggtgga gctactgtag catgtgcatc tgctggtgca gaagtatgtc
    29341 atgttgatgc tgcaaaaggt atggttaatt gggcaaaaga aaatatagaa ttatcaggtc
    29401 ttaaaaatca aacagtaaga tttatagtgg atgatgttgt aaagtttgtt gaaagagaaa
    29461 taagaagagg taaaaaatat gatgcaataa taatggaccc tccttcttat ggaagaggtc
    29521 ctaaaggaga agtatggcaa atagaagaaa agttatacag ttttgtagat ttatgtatgg
    29581 gagttttatc agataaccct ttatttttct taattaattc ttatacaaca ggattttctc
    29641 caatagttct tgaaaatgta ttgtctacaa caataggtaa aaagacaaat acaggagata
    29701 tatacggtgg ggaattagga ataccagctt ccagagatgg taagatactt ccttgtggta
    29761 tatttggaag atgggagaaa aaataatgat aaaagtcata tatgaagata accatttatt
    29821 agttgtagaa aaaccagtta acatattgtc tcaaggagat aatactaatg ataaagatat
    29881 ggtaaatctt ttaaaagact atattaaaaa aaagtataac aaacctggaa atgtatatat
    29941 tggtttaata catagattgg atagaccagt aggtggagtt atggtgtttg caaaaacatc
    30001 aaaagcagca tctagattgt ctgagcaggt aagaagtaag actttcaaaa aaacttatct
    30061 agctgttgtt catggcaaga taaaatctaa ctcagatata ctaaaagatt ttttatataa
    30121 aaataaaaaa actaatatgg taactgtagt gaaaaaaagc cataaagatg ccaaagaagc
    30181 tgaacttaac tataatgtat tagattttaa agaaaatcta agtttagttc aagttaattt
    30241 aaagactggt cgttctcatc aaataagagt tcaatttgca agcagaaaac atccattata
    30301 cggagaccaa agatatggca aagaaataaa taagattgga caacaaatat ctctttggtc
    30361 caataagata gaaatttgcc atcctactac aaaagaaaaa atggaattta catgtcatcc
    30421 acctgacaaa tatccatgga atatatttta aatctcaaat gaggtgatta tatgagtaaa
    30481 aaattttcaa taggagaaat gtctaaactt cataaaataa gcatacagac actaagatac
    30541 tatgaccaaa tagatttatt taaacctgtt catgttgacc aagaaagcaa ttacagatat
    30601 tactcaattg accaattttc acaattagat attataaaat atttaaaata tttaggtatg
    30661 cctttaaaag aaattaagtc aaagcttgat gaaaataatg aagaaattct aaaattacta
    30721 acaaataaaa ttaatatagt ggatgaaaaa attaaagaat tagagcttat aaagaaggta
    30781 ctaagcacaa agaaagaaac tatggaaaaa ggtatgaaag tagatgaagt tggtaaaata
    30841 gtgagaaaac atattccacg aagaagtatc ttatctatag agtatgaaaa aggattaagt
    30901 agtgaagaaa ctatggaact ttccagaaga caaatagcaa atatattaga agataatata
    30961 tctgtgttct atggtggagt aagtggactt gtatctatag ataaattttt aaaagaagat
    31021 aaagttattt atgacaatag ttttgttact gttgaaagag acttatttga tataaaatca
    31081 caaaaacata taacagaaat ttcatctggt gattttattt gtatgacata taaagggcct
    31141 tacaaagaaa attataccgc ttttaagaaa ctggttgatt atgttgaata taaaagaata
    31201 cctattgaaa attatatata tgaaatacct ataatagacc ctctgtctac aaacaacgaa
    31261 gaggaacttc taacagagat tcaaatacaa gttaaaaaga gagaaattga cttaagatgt
    31321 ctagtgtagt aatctagttt acttacacat cttaatatag ttgtctatta tcaacatatg
    31381 atttttctag atagtgattc ctaacagtga gattttcaaa aaataggagg aaatatggct
    31441 aatgctaatt ccctcctatt tttaattaat ccatatcatt ttaattaagc catgtcatca
    31501 cgaagtgcat caataatatt ttcttttttt atcttattaa tagtatacaa cattgtaata
    31561 aatactataa ataaaacact aaatatacta attccaatac taaaccatgg aatcacaaaa
    31621 tcaatatcat ctgtaaccat tactttatga attagccatg aagaaattac tgctatagga
    31681 agtccaaaga acaatgctct catgccataa aaggcacact caaaattcat catcttttgg
    31741 aaatcatgct cagacattcc tacagagcga agcatggcaa gttctctacg acgtaactta
    31801 atattagttg aaattgtatt aaacacattg gcaatcgaaa tcagagaaat cataattatg
    31861 aaagtatagg caaaaacatt ggcaataaaa atgtaattac ggttctcatc catcattcca
    31921 tacatattgt acagattgta ctcattcgta actccctcac tctcaataat ttgctccatt
    31981 tctgcaactg actgagtagg atttttcgat tgaaagctta aactttcaat tcctgtagaa
    32041 acaccaggaa tctcaaactt atctttggct gaataaggag ccaatactct gaagcttgct
    32101 ttcttcacat ctgaacttct gattcctgga ggagaatcag gtggcactac tttgacaaat
    32161 gaaatattca cattttgtct ctcaggtatc tccaacttgc cattagtttc aggagtgagg
    32221 ctaacattca tagaagaact gttgaaaata tcaataatat tattatcctt tgttaccata
    32281 gaaacagcaa tcagttttgc attttgtcca gtatattctt ctgctggtaa tccaagactt
    32341 ttaataatat tcagataagt tctatcatca agaaattgca tatctactgg taattcaagc
    32401 atttcactca tagaatgtga accctcatag ttcaaataat cgtctgtaag ctcacttact
    32461 ttggcaacac atgaataggt cataagtttc tgatacaaac cttcgtaaac accatttgca
    32521 gtttttagct tatcgtaaag cttcaacatt tcgttgtctt tcataccttg tgtagaaaaa
    32581 ataatatcct ggtcagtaac ctctgacctc tgatttgaca tctgttttag gtctgctact
    32641 aaagcacttg tagatataaa tagaactatg cttaaaacaa gtgacaatac aatacttcga
    32701 taacgtttct tgtttctttt aaagtttttc atagcaagaa ctccctcaag accataaact
    32761 cgctgtgtta gttttgatgt cttcacagat ttagattcaa tttttacctc atttgtctga
    32821 cgaatacact ccatcactgg tgtgttggca gcctttcttg ctggtatgta agcagaaatt
    32881 aagattgtaa ccatacttac cactgctgca acgatgattg cagggataga caatgttaat
    32941 gtcaacggaa cgtttacata gagaatattt gcaaagtttt tagctatgac agaaatcaca
    33001 agtccaatac tgactatacc gattgcaaca ccaattggta taccaatcgc accaatgcaa
    33061 attccttcaa atagcaccga atttcgtaac tgttttgctg tagctccaac agatgaaagt
    33121 attccaaatt gatgtgttcg ctcgttcaat gacatgttaa atgaattata tattagaaaa
    33181 attgagccta gcatgattat ggcaagcaca atgccaccaa ccgagtacaa aaacatattg
    33241 aacaaattgt tatcagaaac acctatgaag cgcaacacat tgtcattgaa aatggaagca
    33301 tggtctttag tgctacttat gtaagagcga atctgatgtg gatttttcaa tgtgacaaaa
    33361 aggctaagac tgtcagtctt gacttgttta tcttctttgg ttatcaaggt atatcctggt
    33421 gcagaagatt cttcaaatac gggctttcta cagataccca caactgtata agttttctta
    33481 tcctgtggca caaaaacttc actcccagca gtgtatgggt cactctgacc aagcttttca
    33541 ttttcactca ttcgtttccc tacatccaaa gaaatagtat cacctactgc aaatttgaca
    33601 ccaccatctg tcgcaacttt acttgaaaca agaatctctc tactattttc aggtaatctt
    33661 ccagaaatta aagttatagg caaagtatca aaagcttctt tgctaaatcc agcaataaaa
    33721 agatatggtt tatctggatt tctgttacct tcaagtgttg catagccaat attttcaaat
    33781 gttgcagtat ttgcaacttc atcattgact ctttgttcct gtacaaaaga agaatccaca
    33841 tccaaaaact ggacatgcca atcaccatat tttataatag ctccatttgt catatagttc
    33901 atcaaagaaa ctccaaaggt agtaactgct gtaatcatag cagctgacag aacaactcct
    33961 ataattgtta caagagttcg agtgcgattc tttttcaatc cttgcagagc aactttgtta
    34021 aaaatgttca ttaacgattc accttcctct catcacgcac tacttttcca tctgaaatac
    34081 agataattct atctgcttgt aaagcaatgt tttcatcatg tgtgacaata atgagagttt
    34141 ggtgatattt actatggctc tctttcagta actggataat ctcttgtcca tttttactgt
    34201 ctaagctacc tgtaggctca tcagcaagca taactgctgg tgcattcatc aatgcacgac
    34261 caatggcaac acgttgctgt tggccaccag aaagttgatt tggtaaatgt gtttttcgtt
    34321 cttttaaacc aagtaattct aacaagtcat ttaaccgttc ttgattgacc ttacgtttat
    34381 ccataagtat aggcaatgtg atattttcca ctacatttaa tgtgggtatc agattgtgaa
    34441 actgataaat caatccaact tgtcgcctac gaaaaatagc aagtttttca ttgctttggc
    34501 catatacatc ttgcccctcc agatatatct ttccacttgt tggtacgtct actcctgcaa
    34561 tggaatgtag tagtgtagat ttaccagaac cagaagaacc aatgattgca gtaaactccc
    34621 ctttttcaat agtaagtgag acatggtcaa gtgcagtaac cttattttca ttcttaccat
    34681 aaaccttaca taaatcttca atctttaaaa acgccattat ataagtctcc tttcatattt
    34741 tataaatata tcataggact ttcaacttac atttaagtga catttaaatg agagattcgt
    34801 cactttggaa aacgaataac aaatattgca ccaccttgtg ggtgattttg tgcagtaatt
    34861 gttcctcctt gtctcataat aatcgtctta caaagtgcca atcctattcc ataaccagct
    34921 gtgcttgaat ttttcccacg ataaaatctg ttaaatagac atggtaagtc ttctttttta
    34981 aagcctgctc cgttgtcatg aatagtaagt tgagtaaaca aaaagttgtc ctcacaaatg
    35041 atatcaattt ttccattatc acccacactc tccatgcagt ttttaaatat attttgaatt
    35101 gcttctgaaa gccaatttaa atcacccaaa atccttactc cttttggtat atcaatatgt
    35161 aaagtgatat tgtgcagttc cataggaatc aaaagttgat gaagtgcaga actaatcaaa
    35221 ttattcacat caatttgttc tttttgaaag actacaatac ctgcatctaa acgtgataat
    35281 tttaaaaggg aagtaatcag ccagtccatt cgtataagta attcctctgt ttctcgtatc
    35341 aactcttttc tctcatcttc atcagaagta ttctctaaca gtgacaaaat aagagttact
    35401 gatgtaagag gagtgcgaag ctggtgggct atgtcagcta gtgagtcagc aaggtgttct
    35461 ttttcttttt tcagtgcgta attttgctct ctaatacgta acgtcatttt agttatttca
    35521 ctttgtagaa tagaaagctc accctcatct gattcagcaa tatacagatg gttagcatta
    35581 tgaagcacaa gattaatttg ttctgaaatc tgtgcaatac ttttgtatcg atttttagta
    35641 aacacaaaaa atgctattcc aaaggtagtg gcagaaacaa tagaaagtat tccagtcata
    35701 atactgattg caaatcccag ggctacagtg agaatagtaa ttaataagaa taaaatagca
    35761 agttttcgaa actctctatt tcgaaacata acttcccccc aatctatacc ctgtcccacg
    35821 aacagtcaaa attatttgtg gacttgaagg gtcatcttct atcttctctc gcaagcgttt
    35881 gatgtacaca gtcaatgtgt tgtcattaac aaactcacct gccgcatccc acaattcatc
    35941 aagtaatctt accctcgtaa taatactttt aggattgcta ataaacacca ataacaaacg
    36001 gtattctaaa gctgaaagaa aaacctcatt gccattcttt ttcacaacac cggttgctgt
    36061 atctacataa agcccacaaa tttcaaaagt tgacccaaaa cgcccacttt ttcgtagtgc
    36121 tgttctaatt cgcgcaatca gttcacgtgg acgaaaaggt ttagtaatat aatcatctgc
    36181 acccatattc agtccagtaa caacacttga ttcatcaccg gaagctgtca aaaagataac
    36241 aggaatgtct tgcttttctt tgatttctgt gcaaatcgta aacccatttc catcaggtaa
    36301 agaaatatca ataagtgcca aatcaaattt attcttagca atctctacaa gtgcttcact
    36361 tcttgtggat acatgggtta ctataaatcc ttctgaatta agcaaaagaa taagattttt
    36421 ggcaattgct ttatcatcct caactaaaaa tatccgtttc atttactttc atcctccttt
    36481 attttattag ttttatatat tccagcagag caatagtaca ctactatttt acttatcatt
    36541 acacaatttt cagtagtttc ttttgttctt atataatcca tgcataatac ctccattgat
    36601 ttattatatt tcttataaca taaatacaca agataagaca aaaaacataa tgtaagtgca
    36661 agttttttaa ctcactaact tataaacata cactcctact aacactactt tcttgatgac
    36721 acatcttaca agcttatatt catacatcaa tgaaaaatta aatttatcca tttattaaaa
    36781 taaaaggcaa tagcttctat agctaatgcc ctttatctta aaatgattta aatactatac
    36841 aatttttata aatggctata aataaactca tatagaatat aaaatttatc tacagtcttt
    36901 tgttatacaa aatttataac ctcttataga acaaatttac cactttgcaa acttatcact
    36961 tttactcagc tatattataa acttttaatt tatctttgtt taaatgtttc ttcttaactt
    37021 ctactaaagc ttttagcgta tccagagatg tcattatttc agtagaaaat tcaatagctg
    37081 ttcttctcat tttaaagcca tctcttgtag agtcatttcc tttagttggt gtatttatta
    37141 ctatatcaac ttgtttattt cttatagcat ctaatatgtt tggtctaggt tcttcaattc
    37201 tatttactat atcagcctct attccatttt ctcttaaact cttcgctgtt ccttctgtag
    37261 caacaaaagt atatcctaat tctttcatat cttttgctat ctctataaac tcatctttat
    37321 catgattatt tacagtagca agtactactc ctctttcatc agacatatgt ctacctgctg
    37381 ccaagaaccc tttatataag gcttcttcta aattttctcc tacacctaga acttctcctg
    37441 tagacttcat ttcaggtcct agacttactt caactttaga taatttagac attgagaata
    37501 ctggtacttt tactgatact aattttggct ctttgtaaac tcctgtacca tatcctaaat
    37561 cctttaattt agctcctaac atacacttag tagccaagtc aactattggt actccactta
    37621 ccttacttat atatggaact gttctactag ctctagggtt aacctcaatt atatataatt
    37681 cattttgaaa ttctataaat tgtatattaa ccataccaag cacattaagg tctaaagcta
    37741 tttttttagt gtattctact atcttttctt ttatttcatc agatatattt tgacttggat
    37801 acattgttgt actatctcca gagtgaactc cagctctttc taaatgctcc attataccag
    37861 gtatcaatat atcttcttta tcacatatag catctacttc tatttctcta ccagttagat
    37921 atttatctat aagtactgga tttttatggt ctctatcaaa tgcatcatcc aaatactgaa
    37981 ttagtttttc ttcgttataa gttatttcca taccttgacc accaagtaca taagatggtc
    38041 taactaatac tggataacct aactccttag caatttcaac accttcatta gttgtccata
    38101 caccttttcc ttttggtcta tttatatcta gtctctctag taaatcatca aatttttctc
    38161 tatcttctgc tgcatctata tctctaaagt ctgttcccag tataggtata tttttttcat
    38221 gtaaaaactt agccaatttt atagctgttt gtccaccaaa ctgtagtatt acaccttctg
    38281 gtttttcttt ttctattata tttaaaactt cttcttctgt taatggttca aaatacaact
    38341 tatcagatgt atcaaaatcc gtacttacag tttcagggtt attgtttaca attatagttt
    38401 ctattcccat ttttcttaaa gattttacac aatgaactga acaatagtca aattctattc
    38461 cttgaccgat tcttattgga ccagaaccca atactacaac ttttctctta tcactaacta
    38521 ctacctcatc atattgttca taagttgaat agtaataagg tgatagagct tcaaattctc
    38581 ctccacatgt atcaaccatt ttataaactg gttgtatatt atataaactt ctcaattcat
    38641 ataatttttc tgggcttatc ttcattaagt cagatatacc tttatcagaa aatccctttt
    38701 tctttaattc atgtaaatat tctttatcta agtcttctat ttttagaact tttaattttt
    38761 cttcttgttc tactatccat ttaaatttat ttataaacca cttatcaaca ccagttattt
    38821 ctgatatcat ttctacttta tagcctcttc ttatcatttc agctaagtca aatagtctct
    38881 catcatcagg tactactact ctagccttta attcttctaa tgttctacct tctgatggag
    38941 catgaaccaa tgaatatttt cctgtttcaa gtgatcttat acctttaaga atagcagcct
    39001 caaagttact tcctatactc atgatttcac cagttgccat catcttagtt cctaattttc
    39061 tattggcatg tctaaattta tcaaatggcc actttggtat ttttactacc acataatcta
    39121 atgttggctc aaaacaagca taagtttttt tagttactgc attttctatc tcatccaaag
    39181 tataacctaa agctatctta gctgctactt ttgctattgg gtatcctgta gcttttgatg
    39241 ctagggctga tgacctacta actcttgggt ttatttctat tatcgcatat tctaaactat
    39301 gtgggtttaa agctatttga acgttacatc caccttgaac ctctattgca tttattatgt
    39361 ctattgatgc ctttctaagt agttgatact cttcatcact tagagtttga cttggagcaa
    39421 caactatact gtctcccgta tgaactccaa ctgggtctac attttccata ttacatacag
    39481 ttatacagtt tccatttcca tctctcatta cttcatattc tatttctttc caacctttta
    39541 tactcttttc aagaagaact tgtccaacag gacttagctg tagtccatgt gaaagtattt
    39601 ctcttaattc ttcctcagta tcagctatac ctccaccagt tccacctagc gtatatgctg
    39661 gtcttacaac tactggatat cctatcttat tggcaaactc aagacctgct tctaaatttg
    39721 taactatatc actaactatt actggttgat ttatttcttt cattacttct ctaaataaat
    39781 ctctatcttc gccctttttt atagattcta tagatgttcc tataactttt acattatatt
    39841 tatctaatat accagcatca tgtaattcta cagctaagtt taatcctgtc tgaccaccca
    39901 tacctgcaag taaactatct ggtttttctt tttctattat tttttctata aattctattg
    39961 ttaatggttc tatatatatt ttatctgcaa tttctttatc agtcattata gtagctgggt
    40021 tactatttac taatacaact tcaattccct cttcttttaa tgcttggcag gcctgtgttc
    40081 ctgaatagtc aaactctgca gcttgaccta ttattattgg ccctgaccct aatactaaag
    40141 ttttctttat actatctaat ttaggcataa ctctttctcc ttatctaaac aattttcaca
    40201 gttcttatct tcatcatcta tacaatcaac tttaattact ttattttatc ttaagttcaa
    40261 atttactcat caatacatct atttaataca tctatgttaa ttaaaccaga ctttttgatt
    40321 taagttattc ttgtttttta gttagctatt ctaatgttgt ttattttact aattctaaaa
    40381 atttatcaaa aatatagtca ttatcttttg gtcctgggca agcttcagga tggtattgaa
    40441 cactgtatac atctagcttc tcatgtctca ttccttcaac agtattatca tttaaattta
    40501 tatgtgtcac tttcatttgt tcaggaactt ctgaaacata ataaccatga ttttgagaag
    40561 ttataaatac ttttccttct tctaagtctt taactggatg atttccacct ctatgcccaa
    40621 atttaagttt agcagttttt cctccaagag ctaaagctaa aagttgatgt cctaagcata
    40681 ttccaactat aggtttttta ccaataagag cttttatatt ttctataaca tcttctaagt
    40741 cttctgggtc tccaggtcca tttgacaaga atattaagtc agggtttata ctcaatacat
    40801 cttctggaga tgttgtagct ggaaatattg ttatatcaca tccacgagct ataaatgatc
    40861 ttaatatatt tctttttact ccaaaatcca taacagccac ttttggacca tttcctttta
    40921 tatgctctac ttcttttctt gtaacagttc taactgcttc tgtatttgaa aacttatcca
    40981 atttatgttt aacatcttct aatttactgt cttctaatgt aattatacct ttcattgttc
    41041 cattatttct aagtatctta gtcaaagctc ttgtatctat tccttcaagt ccgataactt
    41101 tattttgctt taaatattgg tctatatcaa tttcacatct aaaattactt ggagaatcac
    41161 ttttctccct tactatgaat ccctttactt gaactttttc agactctgct gatgataaat
    41221 ttataccata atttcctaca agaggataag tcatagtaac tatttgacca tagtaagaag
    41281 ggtctgttaa aacttcacca tatcctatca tcgaagtatt aaatactact tctcctacac
    41341 tttcttctaa atatccaaat gcctttccta taaaaactgt tccatcttct aatattaacc
    41401 ttgctttcat actatagtac ctcctataat tctctttaga caaactaaag aacattaact
    41461 aaatataagc ttttaaatat ctatatctat ttttcacttt tacattctag ttttatactt
    41521 atttacattt attttttatc tttttctatt atactacaaa tttcttaaaa aaaagaagtt
    41581 atctcaaaag taaaaactcc tagaaaaaat aacctctttt tttttattta ataattaaat
    41641 tcttaaacta tacaatcaac ttaatttcta ttcagctata ttgtaaactt ttaactcatc
    41701 tttatttaaa tgtttcttct taacttctac taaagctttt agtgtatcca aagatgtcat
    41761 tatttcagta gaaaattcaa tagctgttct tcttatctta aatccatctc ttgtagagtc
    41821 atttccttta gttggtgtat ttattactat atcaacttgt ttatttctta tagcatctaa
    41881 tatgtttggt ctagattctt ctactctatt tactatatca gcctctattc cattttctct
    41941 taagctatta gctgttcctt ctgtagcaac aaaagtatat cctaattctt tcatatcttt
    42001 tgctatctct ataaactcat ctttatcatg attatttaca gtagcaagta ctactcctct
    42061 ttcatcagac atatgtctac ctgctgccaa gaacccttta tataaggctt cttctaaatt
    42121 ttctcctaca cctaggactt ctcctgtaga cttcatttca ggtcctagac ttacttcaac
    42181 tttagataat ttagacattg agaatactgg tacttttact gatactaatt ttggctcttt
    42241 gtaaactcct gtaccatatc ctaaatcctt taatttagct cctaacatac acttagtagc
    42301 caagtcaact attggtactc cacttacttt acttatatat ggaactgttc tactagctct
    42361 agggttaacc tcaattatat ataattcatt ttgaaattct ataaactgta tattaaccat
    42421 accaagcaca ttaaggtcta aagctatttt tttagtgtat tctactatct tttcttttat
    42481 ttcatcagat atattttgac ttggatacat tgttgtacta tctccagagt gaactccagc
    42541 tctttctaaa tgttccatta taccaggtat caatatatct tccttatcac atatagcatc
    42601 tacttctatt tctctaccag ttagatattt atctataagt actggatttt tatggtctct
    42661 atcaaatgca tcttgtaggt attgagataa tttttcttcg ttataagtta tttccatacc
    42721 ttgaccacca agtacataag atggtctaac taatactgga taacctaact cattagcaac
    42781 ttcaatacct tcgttaagtg accatacacc ctttcctttt ggtctattta tatctagtct
    42841 ctctagtaaa tcatcaaatt tttctctatc ttctgctgca tctatatcat caaaatctgt
    42901 tcccagtata ggtatatttt tttcatgtaa aaacttagcc aattttatag ctgtttgtcc
    42961 accaaactgt agtattacac cttctggctt ttctttttct attatactta aaacttcttc
    43021 ttctgttaat ggttcaaaat acagcttatc tgatgtatca aagtctgtac ttacagtttc
    43081 agggttattg tttatgatta tagtttctat gtccattttt cttaaagatt ttacacagtg
    43141 aactgaacaa tagtcaaatt ctataccttg acctattctt attggaccag aacctaatac
    43201 tatcaccttt ttcttatcac taacaactac ctcatcatat tgctcataag ttgaataata
    43261 gtaaggagat atagcatcta tctcacctgc acaagtatca accattttat atgctggttt
    43321 tatattgtat agacttctca attcatataa tttttctgga cttatcttca ttaggtcaga
    43381 tataccttta tcagagaatc cctttttctt taattcaaga agatagtctt tagttaaatc
    43441 ttcaattttc ataactttta atttttcttc ttgctctact atccatttaa atttatttat
    43501 aaaccattta tctatacctg taatttgttc tatcatttct actttatagc ctcttcttat
    43561 catttcagct aaatcaaata gtctctcatc atcaggtact acaactcttt tctttaattc
    43621 ctctatgctt ctctcctcag atggtgtgtg aactaatgaa tattttcctg tttcaagtga
    43681 tcttatccct ttaagaatag cagcctcaaa attacttcct atactcataa tttcaccagt
    43741 tgccatcatc ttagttccta attttctatt tgctttttta aatttatcaa aaggccattt
    43801 tggtattttt gccaccacat aatctatagt tggttcaaaa caagcataag tttttttagt
    43861 tactgcattt tctatctcat ctaaagtata acctaaagct atttttgacg aaactttagc
    43921 tattggatat cctgtagctt ttgatgctaa agctgatgat ctactaactc ttggatttat
    43981 ctctataact gcatattcaa aactatgtgg attaagtgca aattgaacgt tacaaccacc
    44041 ttgaacttct actgcattta atatatctaa agatgctttt ttaagcattg cacattcttt
    44101 gttacttaaa gtttgagttg gagcaacaac tatactgtct cctgtatgaa ctccgactgg
    44161 gtctatattt tccatgttac atacaactat acaatttccc tttgaatctc ttattacctc
    44221 atattctatt tctttccaac cttttatact cttttcaatt aatacttgtc caacaggact
    44281 taattgtaga ccatgtgaaa gtatttctct taattcttcc tcattatcag ctataccccc
    44341 accagttcca cctagtgtgt atgctggtct tacaactact ggataaccaa ttgtaagtgc
    44401 ataatcaaga cctgcttgta aatctgtaac tatatcacta actattacag gctgatttat
    44461 ttctttcatt acttctctaa atatatctct atcttcacct tttttgatag attctactga
    44521 agtacctatt atctttactc catatttatc tagtatgcct ttttcataaa gttcaactgc
    44581 tagatttagc cctgtttgtc cacccatacc tgcaagtaaa ctgtctggtc tttctttttc
    44641 tattattttt tctataaatt ctattgttaa tggttctata tatattttat ctgccacttc
    44701 tttatcagtc attatagtgg ctggattact atttattaat acaacttcaa ttccttcctc
    44761 tttcaaagac tggcaagctt gtgttcctga atagtcaaac tctgcagctt gacctattat
    44821 tattggtcct gaccctaata ctaaagtttt ctttatacta tctaatttag gcataaattt
    44881 ttctccttat ctaaatggtt tttactatct gtaaataata ctaaatctat attaatgcta
    44941 agaatttatt aaatatacaa tctaaatctt cttttgttgt gtattctgga atgtattgaa
    45001 cactatatat tggtaattcc ttatgtctca ttccttctat agtattgtca tttaaattta
    45061 tgtgagttac ttctgtattt tctggcattt ctgaaacatt atatccatga ttttgagaag
    45121 ttataaatac ctttccagtt tctaagcatt taactgggtg attacctcct ctatgtccaa
    45181 atacaagctt tgaagtcttt cctcctaatg ccaatgctaa aatttgatgt cctaaaccta
    45241 ttcctgtcaa tggctttttg cctattaatt tttttatatt ttcaactata tcatttatat
    45301 cctctggatt tcctgggcca ttagataata agattaagtc aggatttata tttaaaattt
    45361 cttctactgt agtcattgct ggtactatag ttatatcaca gttacaagct ttaagagact
    45421 ctagtacact atttttaata ccaaagtcta taactacaac tttagctcca gtacctttta
    45481 tattttcaat ttcttttctt gtaacatttt ttactgaatc tttgttacaa tgctcttcta
    45541 atttagactg aacatcttgt aatgatacat tttctaaagt tataattcct ctcttagttc
    45601 cattgtttct aataatttta gttaatgctc ttgtatctat tccttcaagt cctattacct
    45661 tattttgctt tagatatgtg tctatatcca tttcacatct aaaattattt gggttatcac
    45721 ttttttctct tacaataagt ccttttactt gcaccttatt tgattcaaca tcttctaaat
    45781 ttattccata gtttcctata agtggataag tcatagtaac tatttgtcca taataagttg
    45841 catctgtcaa tagttctcca tacccagcca ttgaagtatt aaatacaact tctccaatag
    45901 cttcctttag atatccaaat gcttttcctt caaatactgt tccatcttct aaaattaatt
    45961 tccccttcat ataagctacc tcccaaatat tttatctaag cattttctat ttctcttaca
    46021 atattaatag ctgattctct tggattttct gcttttgtta taggtcttcc aacaactaaa
    46081 taatgagcac ctttttttat tgcatctgat ggagttacaa ctcttttttg gtctccaacc
    46141 tctgctgatt taggtcttat tcctgggcaa actgttataa aatcagttcc acatgcttct
    46201 actattttat ctacttcttg cgctgaacaa acaaccccat ctattcctga ttcttttgcc
    46261 agtttagctc tctttatagc taactcttct gttgtcatat tacatcctat gtcctgtaaa
    46321 tcttggttgc ttaatgaagt taaaactgtt actccaacta ctaatggctt ttctatattt
    46381 aatctttctg cttcttccct agcaattagt gcacattgtc tcattccttc catatctgat
    46441 acatgtattg tcattaacca aacattatct ctcactgcag ctctcactgc acttttcata
    46501 gtatttggta tatcatggaa tttaaggtct aaaaatattt ttttcccttt ttctttaaga
    46561 taatctattg ttttaccttt tgtggcaacg tattgctcta gccctacctt aaatatgtct
    46621 acactatctt ctaatctgtc tattagttct ttagctttat caaattcgtc agtatcaatt
    46681 gcaactatca atttttcttt accatttatc atttttacat ctccttttta ataaagccta
    46741 aataatcata aaaaaatcct cacaccaaaa gaggcataag gattttatct atacataact
    46801 ctattcatta gctatgagat atctttccca gtctctctgg actagtttaa aagactttat
    46861 tatatttaaa tttttatttt atactcatca aaaacctcta gaagatttac tagaggttat
    46921 atactaacat tatctataac cctttagtct ctctggacta ctttaaggaa tttagctgta
    46981 atatttttct ttatttatat aactttatgt atctatagga taatttaaag ttttatcttt
    47041 tttataatta aaccactaat tgctttttat gtcaataagt ctttgaatta ttcttcatct
    47101 ttatcaaaca attttttctc aaaatatgat tctgcattat atattgcagc aactggatta
    47161 tgcccagtta ctctatcttt gacaactaaa gttgttatag gagcttccat atatttcatg
    47221 gctaaagtat cgtgaccaac acataatcca agaattacat taaggtcaac cttagcttca
    47281 tttaaaaata aagcttgtcc tattggattg cacattacct catctgaaca ctttgatatt
    47341 gtttgagatg cttctagtcc aattgtactc ttaggcattg ccccattttt acatataaca
    47401 gaaaatactt caaacccatg atgttcaaat attttttgca ctgtttgcat ttctcttttt
    47461 agtccaatac aaaatgctat gccaatcttt ttataaccac actttttagc aaactctata
    47521 atctctttta gtctagtata ttgacaatac ccctctgctt caactaatcc agcattataa
    47581 gctatttttc tattctcttc ttcttcataa agttgctttg ctttttgttg tagttcaatt
    47641 tctctagttg gacatatctt cattaattta tccatatttc cattagaaca gcctctaaga
    47701 ttacattttc cacacttata catatccaat atccccttcc aaaattttat tcatcttgcg
    47761 attcttcttt ttctagagtt acattttctt cttgggtttc ttcttctggt ttcacatgct
    47821 cgactacagt tataaaatat gattttccta ttttattcct tataggaagt ttttcatatg
    47881 aaacatctat tttatttttt atacaagcta tatcaaaatg tcttaaggct acacctaagc
    47941 taaccttatt catatcttca cagtgtttct taggtctctt ttcaaataaa tgaagacctc
    48001 gttcatcctt atggaaatac cacggttgag aattttttac agatggagct cttcttgtca
    48061 attctaagat atctttccac tttctattcc tatttatctt atttatcata tcttttactg
    48121 gctttctatc aggtctagca tatctcgtcc taaacaactc ttcatttttt gctggatatc
    48181 caaatgctat tattatataa ggattttcta ttttgttttc atcatcttct tctgttttta
    48241 ttccagctag ataatctaaa tcatcttcct catcttcttc aaaattctta ttcccaatat
    48301 ctacaaattc caagatatct tctctcttta agtttccttc caaccagcaa gtagctattc
    48361 ccaatgttgt aaggcgcaaa actacacctt ctgtagcaaa tcctatattc tgtaaatagt
    48421 cctcaccttt gtctgatgta actactatat aatgaggtgc ctttacttta cattccttac
    48481 ccatcaaaaa atgtattata tgacctctat caacaacatg tgctttaata tttaaatctt
    48541 catttaagta ttctaaattt ttacaacttc tttttatttc ttccatcaat ggctttttta
    48601 tcttcttact ggaaaaattt cttacagatt ttctataaaa aatggcttca taaagctcca
    48661 tttatgccct cctaactgaa atcttctgac gtataaactc tataaattta tataaatact
    48721 ttatattttt tatagtttta tttccttttt cctcctgccc tattttgaaa ttcataagaa
    48781 tatctactct agtttaatat agcattcaaa aggcttaaat tctaccttat caatgtctat
    48841 acattagcat aattttttta tttgattttc tatgctaatt taaataacaa cactagctat
    48901 taccttttta attaagcttt gccagaaaaa ttttttttca tttataaata tctatctcat
    48961 tattatatta taagtttttt tcggtattct tgtatagctt ttcactaaaa aagtattttt
    49021 atttctactt taatattatt atcaacaaaa aacatactgc ttaaataagt ttgttatcct
    49081 cataatttgt tttaattaaa atattttttt tatttctcaa tctataaagt ataaatattt
    49141 tgaatatgac ccaaaatcta agtaaagtta taatatttta taagttgttc aatattaaaa
    49201 acataagtaa tgttataata ctttataagt tattcaatat taaaaatata ggaggataaa
    49261 tatgaattta aatagaaatt tagaaaaata cgctgaatta gcaataaaag ttggagttaa
    49321 catacagcca ggtcaaattc tacttataaa gtcaccaata gaatgtgctg attttgcaag
    49381 aaatgcactt aaagaagcat ataaatgtgg tgctaaaaat gtttatatag agtggtctga
    49441 tgaagaaagt actcttatta aatacttata tgctccagat gaagcatttc atgagttccc
    49501 caaatggaca gcagaacaat atgtagatat agcaaaagaa ggtggggcat ttttatcagt
    49561 ctatgcccaa aatccagatt tattaaaaga tgttgaccct gaaagagttg caaattttca
    49621 gaaggcatct ggaaaagctt taaaagaatg gcgttcttac actctaactg ataaatgtaa
    49681 atggagtata gtctctgtgc caacaaaaga ttgggcaaaa aaagtgtttc caaatttatc
    49741 agaagataaa gcaatagaaa aactgtggga tgctatattt aaatgttcaa gagtagatgg
    49801 tcaggaccct ataaaagcat gggaagaaca taatgaaaat cttaaatcta aaatggactt
    49861 tctaaataaa aataacttta aaactttaaa atataaatcc tcaaaaactg atttgactct
    49921 agacttgcca aagggtcatg tttggctaag tggagcatcc aaagacccta atggaataag
    49981 ttttaatccg aatattccaa ctgaagagat ttttggaatg ccacataagt ttaaagtaaa
    50041 tggaactgtt tatagtacaa aacctcttgt ttatggtgga aacataattg acaatttctt
    50101 cttaacattt aaagatggta aaataataga tttctctgct gaaaagggac tagatacact
    50161 agaaaaactt attgaaacgg atgaaggctc tcattattta ggagaagttg ctcttgttcc
    50221 atacaactcg ccaatatcca atacggatat aattttttat aatactctat atgatgaaaa
    50281 tgcttcttgc cactttgcaa ttggttctgc ttataagact tgtctggaag gtggaaacaa
    50341 tttaaaagat gaagaattgg atgaacatgg tgtaaatgat agtttaacac atgtagattt
    50401 tatgattggt tctgctgata tggatattat tggtgagact tatgatggaa agcaaataca
    50461 gatttttaaa aatggtaatt gggcttttta acatatgatt ttaactaaaa agggctgatg
    50521 gaagttatac cagacttccc agcccttttt aatgttgatg ataaatattt tttatattaa
    50581 ttaatctcat tattatagat taattcctat tgttttaaac ataagtatct aaaacttata
    50641 tttatattat atataaaata tcctatttag taaaaccttt attttaattt atatgctaaa
    50701 aatttaactt tgctatttca acagcagact ttgcatcctt tgaataataa tcagcaccca
    50761 tttcttcagc gtattcttct gtcaaaactg cacctcctac aaataccttt gcatttatct
    50821 cattatctct cagtgcctga attgtatctt tcatactttg aacagtcgta gtcataagtg
    50881 cacttaatcc tactaatttt atatttctat ttttagcaac ttccactact tcttcaatag
    50941 ggacatcctt acctaaatct ataacctcat atccataatt ttctagcatt atttttacta
    51001 tatttttccc aatatcatgg atatcacctt ttactgtagc aactattatt tttcctttgg
    51061 atacattatt gctactttta cttaataaag tttcctttat tgtatttaat gaaactttta
    51121 ccgtttctgc tgattgaatc aattgtggta aaaatatatc tccactatca tatctttttc
    51181 ctactttatc aagagcagga attaaaatct catctaatat ataattttca tccttctctt
    51241 ttaaaagatt cagtgttaca ttttttgctt catcttttaa tcctctttca actaaaatat
    51301 ccaagggcaa atctttatca atctttgtag atgaatccga cttttttgaa ttatttatat
    51361 tgctatattg atttatatag tttatacatc ctttatctgt gttatttaat attttaaaag
    51421 aattgatagc ttccatcata ctatattcat ttggatttat aattgctaaa tcaagccctg
    51481 cccctaaagc taatgttaga aaagaagcat taagtgcttt cctatttgga agaccaaatg
    51541 aaatatttga aacacctaat atagttttta ctcctagtgt ctttaccatt gttatagctt
    51601 ttatagtttc tattgcttct tcttgttgtg ctgaaacagt taatgataaa cagtctataa
    51661 atatatcttt tggttttatc ccataagaaa ctgctctatt aactatcctt tttgctattt
    51721 caaatctttc ttcagccttt ttaggtatcc ccttttcatc aagtgtaagt ccaaccacac
    51781 atgaaccata ctttttaact attggtaata tactttctaa agactcctct ttgccattta
    51841 cagagtttac tattgttcta ccattataat atctaagtcc ttgctctaag gcctctacat
    51901 tggaagaatc aacttgtaaa ggtgtatcta ctactgcttg aatctctctt attaattttg
    51961 gcattagttt tttttcatca atctctggaa gaccaacatt tactccaagt atttgtgctc
    52021 cagcatttac ttgttctaaa cctaaattta tagcataatc aacattttca ttttttaatg
    52081 cttcttgtag agattttcta cctgtgggat tcaatctttc tccaacaact gtaggcgatt
    52141 gtacttccac aaattttgat ggtgaacaga ctacacattt atcaattttc tcgatacatc
    52201 cctttgtaac agaatttata ttctcagata tttcttttat aaaacttgga ttcgtaccac
    52261 aacatccacc tattatagta gcaccaactt caacgaactt tttaacccct tcaaaaaatt
    52321 cttttgcatc aacatcatat atagcctctc catcaactat atttggaaga cctgcatttg
    52381 cttgaaccat aacagggact gtagctcttg atgctatttt ttcaactatt ggtaaaagtt
    52441 gtttaggtcc taatgaacaa ttaactccta ttgcatctac acctagacct tctatagtag
    52501 ccaccataca ttctggcata catccagtaa aacttcttcc accttcatca aatgtcatag
    52561 tacagaaaat aggtaaatca gagttttctt ttgctgctaa tacagctact ttagcttcat
    52621 ataaatccat catagtctct attactatta catcaactcc agatttaacg ccttgtagta
    52681 cttgtctttt aaatatttca tatgctttat caaaacttaa agtacccata ggctctagca
    52741 tttctcctat aggaccaata tctaaagcta catatcttgg tttagtatta tctacatttt
    52801 ctatagcttt tctagccacc aaaacagcat tgtcaatcac ttcttctaca gtatacttac
    52861 tatctaattt tagttcatta catccaaaag tatttgtaag aattacattc gaacctgcct
    52921 ctaagtatgc tgtatgtatt tctataagtt tatctggatt ttgaagacca aatacttctg
    52981 gattttcacc taactttaac cctttttgtt gaagcattgt tcccattgca ccatcaaata
    53041 ttaatatatt atttttcaga tattgtctta tttccacaag agttcgctcc ttttctatat
    53101 gtacagtttc tatagttttt acaattttca cacgactttt ctttcttaga tttatttatt
    53161 cttgtattag aaatacctat aatagccact actgactttc tcggtatcat aattccatta
    53221 gaagtaattg ttagacctat ttgtttttga gcattcaaaa cgtttaatat atctatattt
    53281 ttttctattg gtaaatctcc atatcctggg ctatatcgca tagttataaa tttatcttgc
    53341 tttaaaaaaa ccttttctaa attattttga acaatgtcac acacttcttc tattgctgtt
    53401 gttccacatg aatcaattat tagtcctttt gttaaatttg aataagagtg tcgtcttatt
    53461 tctttttcta tatctatccc tatagtagct gccataatta cacactcatt acattctttt
    53521 aaaagttcat atacatcttt actctctaat gttaaatttg ttccctctaa ttctacaaca
    53581 ttatctttat ttattttaat aggataaatc ctagataaat atctaggatt tattttattt
    53641 ttagttatag ctacacattc atcaatagta tatttaaggt ctttatctat ctcttgacct
    53701 ctgtattgta aatatcttaa aacttcactt tgatttatgc ttatatcttc tcttccaatt
    53761 aaattattct ccatatatat ttaaagaaaa tcctttatct aaaacatctt ttgcatattc
    53821 ctttgcccca aataaagata agtctctgta gtttccacat tctatagctg tagctgctgg
    53881 cattttatct gattcaagaa ctttttttaa tgcttcttct aaaccaatct taactgtttt
    53941 ggcatctaca tctccccata gtattaaata aaatcctgtt ctacatccca ttggagataa
    54001 gtctattaca ccatctaatg tatctcttaa ataagtagct aaaagatgct ctaaaccgtg
    54061 catagcagca gttccaaaac tttctacatt tggctgtaaa aatctcaagt caaatttagt
    54121 tactttatct ccctttactc catcaagtac actacacttt cttacaaaag gagcttttac
    54181 ttttgtatgg tctagcttaa aactttctac tttttccatt atttaatcct ccattatact
    54241 ttaaaatttg ttacattaat tctaaaaaaa actcttccta tctattattg ataagaagag
    54301 tatattattt caagtcatct catcgttgtt agcaggacca cctgataaaa ggttggtata
    54361 ggatcactga gctaactctc tcccctaact cttgataagt atcttattaa actgacttaa
    54421 attatatatt acttttttat ttttgtaaac actttattgt tataatattt atatcacata
    54481 atcgtacttt tattttataa ctaagctgat tgtattattg gcagttgtac ttcaaacata
    54541 gtttgatatt tatcgcttga aacagtaatt tctccatcat gtaaatttac aatatttttt
    54601 gtaatcgcaa gacccaatcc agaacctcca acatttctat ttctcgattt ttcaactcta
    54661 taaaatctat caaatatatt tggtaaatct aacactggaa ttggttcccc ataatttatc
    54721 acttttacaa ccgccatatc ttcctttttc tctgtgacta tatctacata atgcccatct
    54781 tttccatatt tcacagcatt agttataaga ttttcaaatg ctcttaccaa tttatttgga
    54841 tcagctttta caattaattt ttcttcatta aaattaattc tactaaccat aaattcttgt
    54901 ttaaaataaa tttcaaattg agatactact tgacttaata actctactaa atttatttct
    54961 attttgttta attttattgt attattttgc attttagtca attcaaacaa atcatttata
    55021 agaactttta aatttttcga tttttcatat gcaatatcaa cataatacat catctgaact
    55081 tcatctttat acttaccttc ttctatcact cctaaataac ccattatgga tgtcaaaggt
    55141 gttcttaagt catgtgacac atttgttatt aaatctgttt ttgtctgctg agcttgtctc
    55201 tcttcaatag ttatatttct aagttgatgg actatattat tgattttatg tgctagttca
    55261 tcaatatcat ccttttcttt atcctttaat atatctaaat catactcaat atctatactt
    55321 ttttctaagt taccttcatc cattaaattt acagcacttt taatgatttc taatttttga
    55381 ttttttctat tagtctttct tataaaatct acaatttgct tatttctctt gtacgatata
    55441 atggaataaa ttgctaatga tgtgattgta aataaaaatg gataaaataa atcataccct
    55501 ataagacttc tgaaatctct tgcttgatat acaagttgat taactacaga catatcacta
    55561 ttgacatata atgattttat tatatacata cttgttaaaa taagcattga agttaaagca
    55621 cagcttatta taagatctaa tatgggtcga aacatatgat ttaataaact tttatttttc
    55681 aattttatat cctactcccc atacagtatg aattattttt tctccatctg tatatttttc
    55741 aattttatct cttattctgc tcatatgaac cattacagta ttattagatt ggtaatattt
    55801 ctctttccat accttttcaa atatttcttc tgtactatat actctgcctt tattatttgc
    55861 tagtaaatat aatatatcaa attctcttga tgtcaaaatt atttcatttc cagccactgt
    55921 tacactatgt ttttccttat ctataattac tactccaacc tttatgacat ctttatcttc
    55981 attattagca ccactaaaat aatatgctct tctaatcagc gacttcactc tcacagtaag
    56041 ttcaagtggg ttaaatggtt ttgtcaaata gtcatctgca ccagtcatta tcccttgtat
    56101 tttatccatg tcttctgatt ttgcacttaa cataagtatt ggtatattca aactttctct
    56161 aacttttcta caaacttcta tcccatccat tttaggcatc attatatcca atatcattaa
    56221 atgaatattt tcctttttta aaatatctag agcctctttt ccatcttcag ctttaattac
    56281 attatatcca ctatttaaaa gatatatctc tataaggtct cttatttcct tttcatcatc
    56341 cacaacaaga actgtattat tcatttttac acatcctaac ttaatctttg tatatagctt
    56401 tattcatata aaattatact atattttagt tagtgtaatc tataaattta ttaatttcta
    56461 aatttccaat ataatacaaa ttatttacac atttatatta tttattttgt aaatattctt
    56521 ctaaagttaa tccttttgaa taaatttcct cggcagcatc cttaccaaca tatctaatat
    56581 gccatggttc atatgctgta cctgttatat cttctttacc ttcaggatat cttattataa
    56641 atccaaactt gtgagcattt tctgccaacc atttagcttc ttttgtactt ccaacaaacc
    56701 atctttctgg atttgttaaa tcaatacaaa gtccagtttg gtgctcactg taaccaggct
    56761 ttgctacata tgcatctgcc ttttctcgtc cctgagattt tacccttctt gtataagtat
    56821 ccagttgagt atcataagat ctgtatgctg aagaccctaa aaactgtatt ccttctgaat
    56881 tagcttgctt aactaaatct tcaactgcct ttgcaggttc tcctgccatt tgtttttctt
    56941 cctctgttgc ttcttcaaca aaaggtatgt ttaccttagt aatattttca ggagtatagt
    57001 ttttgctaat tccatttgtc ttgtttacca ataatatatt tgatatacta tttgagtgat
    57061 ttttattttg agaatttgcc tcaacatctt gttctgaatc atgttgagca gctactattg
    57121 gatcgttatc tttcttaagt aatctatctt tagatataaa tacacttata aatactacta
    57181 aaataatggc tcctattaat ttaaattttt tcataattaa atcttctcct ttttgttatg
    57241 tttgctataa tgttaatttt agagtataag acttaagtat tttataagta aatcttaaat
    57301 aaatcttaaa tttaatattt ttaaaggatg gtgataaaat gtctatacaa aaacttctaa
    57361 gtaaagctcg taaggctata caagattttg atatgataca agaaaatgat aaaattgcgg
    57421 ttggactttc tggtggaaaa gatagtttaa ctttacttca tatacttaaa agttatcaaa
    57481 gattttctcc acaaaacttt gaattgatag ccataacatt aaatactgga ggtgttgata
    57541 attctccact agataaattg tgtaaagaaa taaatgttcc tttttatgaa tttcaaactg
    57601 acataaaaga aattgtattt gatataagac aagaaaagaa tccttgtgca ttatgtgcta
    57661 atttaagaag aggtgctttg aacgataatg ctaaaaaact tggatgtaat aaagtagctc
    57721 ttggtcatca taaagatgat gcaattgaga catttttaat gtctatgttt tatgagggta
    57781 gagtaaattg tttttcccca aagacatacc tagacagaca ggatttaaca gttataagac
    57841 ctatggttta catagaagag tatatgacta agaaaatttc aaaagattct aactatccta
    57901 ttatcacaaa tccctgccct gcaaatggtc atactaggag agagtacata aaaaatctta
    57961 ttgctaattt aaataaagag atgcctgatt ttaaaagaaa tgtatttggt gctttaaata
    58021 attctgagaa attgtttata tgggataaag agaagataaa aaattttaaa taataattaa
    58081 aatttttaaa taaaaaagca agattgtatt aattgtaaat aatctttata taatctacac
    58141 aatcttactt ttttatttat tatatgttat tatctttaat ctatatttta atagttctta
    58201 atagtattta ttttgtctaa tacattaatt ataacttaaa tattttatat attaatttaa
    58261 tctattaatt cattcaatct actggtttaa tccattttta cagtatatac atctacatat
    58321 tataaaaagc aaaattatat tttctaaata ttttatgtta gattataata ttaaattcta
    58381 ttatctctgg tatattaaaa aatctaaatg gtaactttgt acttccaaga cccgaactca
    58441 catataaatg atttccattt atatcataaa accctttagt atatttcctt ccatatggag
    58501 gagtaactaa tgctccctta ataggtaatc ttatttgacc accatgacta tgcccagata
    58561 gaactaaatt cattgtatct ttactaagca tatctactaa atctggttca tgtgctaaca
    58621 ataaattaaa acttttatta tctatttgac tctccagata ttttatatta ggatttccat
    58681 ttaatatttc atcaacacct aatatattaa tatatttatc atcttttaat tttatttttt
    58741 tattttcatt tactaaaaga ttgaagttgg aatttttcat aatctgccta taatacctag
    58801 gaagtttata catataatca tgattgccaa atactgaaaa ttttcccaac ctagcattca
    58861 tacttgataa aatagttgta atttcatcta cacttggatt tttattggag taatcaatta
    58921 aatcaccagt aaatactatt atatctggat tcaaagtgtt aatcttatta gctacttttt
    58981 tgagattctt agttgaataa aaactaccta tttgagtatc tgaaatttga actactttta
    59041 cactttcaga tttactctca attgtatcat tttttatcaa tgctccattt tcacttatat
    59101 tatatttttt cacaattaat agactcggct ctatcgcaac tgagtatata aaaatcaaaa
    59161 taaatattaa gataaaaaat tttaaaaaat acttaatttt tgagttcaaa atatctacct
    59221 acttatttat ttttttaaac tatttgcatt acagactcaa ctttgttcat ttttctgtca
    59281 tgcatttttg gcttatttgc tgaaaaccat ttatatgttg ctgtaagacc ttcttttagt
    59341 aacacgtttg gtatataaag cccatgttca ataagcttat ttatatcaag attaaagtct
    59401 atatttctaa atgggaaata cgttctttct ctaaactcta ctttttccat atctacatat
    59461 tttattatag gttctttgcc aataatttct ccacatgtat atataaggtc atcccaagaa
    59521 attaactgtg gatttgtcac attataggcc tctcttacat gaggattttt cattatgctt
    59581 tccaatacct ttaccaaatc cccaatatat ataaattgat tactaacttg ttttcctttt
    59641 ggtactggta tcttttcatt tttttctatt ttttcaaaga aataatactc tctatataaa
    59701 ttattatttt caccatatat gtaagttggt ctaataatta tatatggtat agggctattt
    59761 ataataaaat cttcagcctc ttttttattt aacccatatt ttccccagtt ttcattttca
    59821 cctttctcat tttcttcttt tatatttctt ccactatctt tatatactgc tcctgctgac
    59881 aatactatat acttttttaa gttatccatg cttataaaat caatcagatt acttacatct
    59941 tcttttgtat atgctgtcat atcatatatg taatcatatt ttcttcctgt gataatgttt
    60001 tccatatctt ttcgaacttt tctatcacaa attagatgtt ctttaaaacc attataatct
    60061 atttcctttt taccatttgt aagtatatca atttgatacc cacatttaat caagcgctta
    60121 gcaagtgcag aacctatgaa gtcgcttcca cccataatta aaatagattt cattttaagt
    60181 gcatcctcct cttttttaaa tgacttcctt aactataata tcatattttt aaatatgcga
    60241 caccattttg taatattttt gtctataaaa gatatttata acaaaatatc ttttatagac
    60301 tctacatttt cgacaatata agtaggttca ctttcactaa tctcttcaaa agaaccatac
    60361 ccatacaata ctccaataga atctatacct atctttttag ctccaattat gtcatacttt
    60421 ctatctccaa ccataataac tttatcttta tcttttacat tacataggtc tagtacatat
    60481 tgtataactt catttttatt cactcttgta ccatcaagat tgctacctgc tatatattta
    60541 aaatatctat ctatatcaaa atatctaagt atagtttctg caaaaactgt tggcttagaa
    60601 gttgctacta ataatatttt accattttta tagagcattt ctaatatctc tttcatattc
    60661 tcataaattt tattttcaaa tatcccttta tcagcaaaat attctctata cttttcaaca
    60721 gcttctttag cttttttatc ctcaaattta taatattcct taaaagtatc atgtaatggc
    60781 ggtcctataa attgttctaa gttgtccaaa tcttcttcta tgccaaagct atttaaagaa
    60841 tactggatag actttgttat tccttcttta gggtctgtaa gtgttccatc taaatcaaac
    60901 aatattattt cataattttt cttcatattt cagtcctcca tatttataaa aagtaatatc
    60961 ttatatatta agtttatcta ttttaaaaag ctatagtaat agaagtttct aatactatag
    61021 cttaagtacc aattaaatct tatatattta ttttaaaaat aaatttaaac agctctattt
    61081 aactgttata gctgaaactg gacatccttc ttcggcttct ttacataaat cttgtaaatc
    61141 tgctggtatt tctccttcaa ttgctactga atgcccttca tcgctcatac taaaaacgtc
    61201 tggacatgtt cctatacatg ctccacaagc tacacataca tccttatcaa caaatgcttt
    61261 catactaaaa tacctcccct aaaattatta ttttttaatt gttgtttcct tagatattta
    61321 tccaatatat accaatttaa acatatattt attattttat cactattgtt tagtttatta
    61381 tagtattttc gtatccatgt ctataaactt cactgctttt catccatgat tttacagtat
    61441 attgcaatct taatttttta tttaaaacaa gttcattatt attgtagtct tttataatat
    61501 cattacactc ctccattgta aatattgtaa aatcaccttc tccaccaatc tttattctgc
    61561 ctttatttcc atgtaaatcg aaaatctttg ttgggtattc agttactttt tctatacact
    61621 tttctaggga tatcccaagt tccataattt tatttataac atttaaaaga gaatagttta
    61681 cgtctttcat gttttttata tgcatatcag tacttattag gtcaggctct aaaccttgct
    61741 ttattgcttt tttaaaaact ttaaaatcaa attggtccac tccatgacat acatcaaaca
    61801 atactcctct attctttgca tttattactg attttcttaa tgtgccagat tctttaagga
    61861 ttccatttgt actatttcca tataccggtg taaccacatc tccttttccc aaaatattca
    61921 ttacttcatc tatatatgat ggatactctc ctatatatac cactaagggt aaatttaatt
    61981 ttttagcaac ttgctttgat ttcttaatta tatctatacc actttcatta gattgaaatt
    62041 tactcgcttt tacttttata ccctttatct tttctatatt tttttctaca attgactcaa
    62101 ccttgtcaaa atttataaca tctaaagaag ttgattcatt caatatattt agtccctcat
    62161 ttgtaacatt taaaaaagaa tatacttctg ttttacactc atccatatac ttttttttaa
    62221 aatcatagta gtttgaggga ccagctgtac ctgcatcaaa tataactgta gaaccttttt
    62281 caattccaat tgaatcagaa tccatacctg taggtaattt tctcttataa caatgggtgt
    62341 gaacatctat aaatcctggg gaaatataca tattatcggc atttattatc tcgaactctt
    62401 tatttgtaag taatttttct tttcttattt tctctttaag gttcaatcca atagcatata
    62461 ttttcccatg taaaaccaag atatctcttt tttcaaattt gataccatct gttggagata
    62521 ttattgtccc atttcttata agtaaatttt tcatttattc cacatcctaa ttacaatata
    62581 atttctctaa tagcttttct tacataaaga aaataagcct aaaaataaaa atattttaga
    62641 cttattcact atattatact atattaatta tattaaatta aataaaatct ttaatttact
    62701 ttaagaagca attaagtatt tgttgctcgg cttcttcttc agtaagacct aatgtcatca
    62761 tctttagtat ttggtctcct gcaatctttc caatagctgc ttcatgtact aaaagagcat
    62821 ctggatgatt tgcagcaatt tcaggtatag cactaatttg agaatttccc ataattattg
    62881 aatcacattg aacatgtgca gaacaaaggg aatccccaat aacacaagga ttaaactttt
    62941 gcttagaatt atcttgccca actgtacgag aaactacttg agcagaagag ttttcaccct
    63001 ctaagataac cttcatatta gattctgcaa cttgattacc atgagttaat aatttctcaa
    63061 atacaactat tttagctcct ttacctaggt ttgcatccat ttctctttta gttgaatcta
    63121 cacccttaat ttgaattgtt tccatttcac aatatgaatc ctcatccata ttgacaatag
    63181 taactggatt taaaattctc tttccttctc catcaccttc accataatgt ttttctacat
    63241 attttaggcg agctccttta cgtaagaaaa atctatgtat accattatgt tcactatcat
    63301 cacaaccaca gttatgtata ccacacccag caattataac aacatctgca ttttctccaa
    63361 tttcaaaatc attatatacc atatcctgta caccagcctc tgttactatt actggtatat
    63421 gtacattttc tccttttgta tttggcttta ctataatatc tattccaggt ttatcagttt
    63481 taggaattat agttacattt tcagttgaat gtctctctac tccttgccca tttttacgta
    63541 tattgtatgc tcctaatgga gttccacgaa gttcagcaac tttttctaaa agatttaaat
    63601 ctattttgtt catttaattt gccttccttt ctaattaatt catgtctttc attaattcac
    63661 aacttgaatt aacttgacac atgatttcag gtaatatagc ctcttttgtt ccatggcttt
    63721 ttactgaacc atcttgtaga acaattattt catcagctaa ctctaatatt ctttcttggt
    63781 gagaaattat gattatagtc tgattagact cttcatgtat tttcttaaaa ctttcattga
    63841 gttttccaaa gctccaaagg tctatccctg cttcaggttc atcaaatata gaaaccttta
    63901 aatctctagc aaaaagagtt gctatctcaa ttcttttcat ttcccctcca gaaagagagt
    63961 tatcaacttc acgatttaaa tagtcttttg aacacaatcc aacatctgta aggtattggc
    64021 aacatacatc agtagacaat ggttttccat gagcaagtgt aagtaaattt tcaactgtca
    64081 taccttttat tcttggtggt tgttgaaatg cgtatcctat tccttttttt gctctttctg
    64141 taatactaag atttgttata tcttctccat ctaaaattat ctgaccactc gtagcttttt
    64201 caattcccat aataagctta gcaattgtag attttcctcc accatttgga cctgtgataa
    64261 caataagttt tcccctctca aatgaaaggc taacatcatt tattattcct agttcctcat
    64321 tgttagactc aacattaaag gaaagatttt ttatttcaag cataataccc ctcttttcta
    64381 taaaatatta cattaatatc cattctttta ttatatcagt aatttttata tatcagcaac
    64441 tctaaggaga taaaatgtat attaaataat aaaacaaagt tattgaaaag taaaaaagat
    64501 gagttttatg taaactcatc tcagaaattt agtatatcaa cttatatgta tttaaaattt
    64561 aaccttctat atactctaat attatttttt gattatcttt taacataatt tcttcttttt
    64621 tagattctat tccattcttt tttatcttta cctcagctac aaaggcatca ttaccttcaa
    64681 ccatttctaa tagttcatac gcttttttac gacctatttt agttgctata tcttttagta
    64741 ctgccatttt cttaaacatt ttatcacctc tactcaaaat ttacacttaa tttttaatta
    64801 tataattcta atcctagact agtttataat aattattgtc tctaattata tcagatattg
    64861 agtaaattta atactttgta aaattattta tcctctctaa ccaaataatc atttccatct
    64921 tggtctttaa aagaaaacat ccttccatat ggcatctcca ttaattcccc aacctcaacc
    64981 tcgttatttg ccatttgttc ataagttcca ttaatatctc ttgtacttaa aattattgat
    65041 ggatgagata catttatctc tttgttttgc ttcatcatta gatttttatc atacaacaca
    65101 aatgttgtaa attcattttt acttggtgct acttccaccc atttcatatt tggacccatt
    65161 tccttttcat aagttactac aaagttcaat ttttctgtcc aaaataactt tgcatcctct
    65221 tgattattta catagagagt tatttttcct attttattta tcataacaat acccaccttt
    65281 attattaaat aaatacctaa tattttttat atttaataat atacccatat atattatttt
    65341 ctatagatat atatttctaa tatttatcgc caaattatgt aattctgctc aatatataat
    65401 ttataatatc catactatta tagcctttat ttatgtaatt taatcacctt atatatcata
    65461 cttataatta tgataataac tacataaaaa atcacttcta aatagagtta tccatctaaa
    65521 agtgatttca tatattctat gcaactttgt gttttagcca ctttgttcct cttaatctta
    65581 aacaatataa agtccctcta acaagccaat cagtatacat acctatccaa attcctaaca
    65641 ctccaaattc taatacaacc cccaatacgt aacctgtaaa aattctaaaa atccacatac
    65701 ctattactgc agtcatcatt gtatatctag tatcaccggc tccctttagc cctgctgata
    65761 atacaaagga tataggccat attaccatag ctaaacaatc acttcgaatt aattgtgttg
    65821 agatgtcaat tacactagca ttttgagtat acatacttga aatccaaggt gcaattggta
    65881 taaatatagc tcctactata aataaacaaa ttgttgcaaa tttagttaaa tataataaag
    65941 tactcttagc tcctttaata tctccacgtc ctatatactg tcccaccaag gttgtagcag
    66001 acaaagctaa agcattccca attacattta ttatggatgc aattgacatt cctattgcat
    66061 tggatgcaat tgctgatgtt cccatagtaa ctataaatac ttgaacaatc aatttacctg
    66121 cattaaaaag tagttgttca actccagctg gtattcctat attaaatata gacttttgag
    66181 tttcaacatc aatcttaaat ggaaatattt tacccataga tataaattcg tttcctttaa
    66241 ataaaactct tataattact atacatccaa ttattctagc tatagcaata gatatagctg
    66301 cacctgttat gccataggat ggtgtttgca aatttattcc tagaggattt aaatcaatac
    66361 catatataag tatatatcct aatgttacat ttactatatt cataaacata gtcacataca
    66421 taggtttctt taaatctcca caccctctta aaataccatt tgctatttgt tgtgtcgcaa
    66481 taaatggata cgtaaataat gtaaactcta tgtataattt tgcatttgat tttaccaatt
    66541 cttctgcgga accataaaat aaattaatta caccagttct aaaaacccac atcaatattg
    66601 ttattgtaaa ggataatatt actccagaca ctagagcctg cttaatagtt tcattcacct
    66661 tttcaccatc tttttttcct atttgttgag ctacaacaac agtagctcca acagatagtg
    66721 cagcaaatac agatataaat atattgttta ttgaatcaac cattccaact gcagatacag
    66781 cttcttcccc aatatgacct gccatcattg tattaaatac tcctaaaagc atgacaaacg
    66841 tctgctctat cattatagga attgctaact ttataacatt tttccttata aacatcccta
    66901 ttcctctttt ccctctttat ataaatttaa tttttaatta gtttatcgaa ctgtaaattg
    66961 acaatgcaaa gtttagaatt gtattgttcg cattataata tactgctttc aaataatata
    67021 aatcttgttt aatatcattt gaacacagta tatctttata attatcttat gtttattatt
    67081 ttttatggat accacattta aaatatttat taatttaata taaatatttt ccgttattat
    67141 taaaagtagc tatatttcgt taatattgta tcactatcgt gtagcaataa caataagtac
    67201 attttatata ttttttataa tattatttaa tcatccaaac ttttaccact ttttcaatat
    67261 ataaaatatt acactttaga tgtaacaaaa tcgcatccat ttaaatattg tattttatag
    67321 actaatttta ggatgtgata ctttggttaa tttaaatgca aataatctaa atgtaaatat
    67381 ggtttatcct atttcttcca cagcacccat acgtttcaga agatatactg tttcatattt
    67441 agaaaacatg gaaaatattt atttaactat agcaacatac tttgatacac ttggtttagg
    67501 cacaatgaat atcgacaaag tttatggtca atgggcttgg tttactgata atatatatga
    67561 tttaaatcta tttgtttttg taggaaatta tccttatcaa attgctaaaa acagatatga
    67621 tacatttgta gatattttgc cagtagctat tacttctatt gtcaatggag atagagtatt
    67681 tttaatttca aatccttgtt tgttaaattc aaaaattaca gttagattta tatctagtca
    67741 tcctactctt aatagaacag ttgattatgg caatattaga gattttattt tttaaaactg
    67801 caacatgatg tgctattaaa aaatacccta aatttaatga tattattaaa taactagaat
    67861 atttttaatt ggcacatcat gcctagctat tataaattca taatattatt ttacttaaga
    67921 taagtactgt attttatcta cttgtatatt tttatttacc tagtttctca gttctatatc
    67981 ctatttcttt attagctagc ttataacctt cttgtatcat ttcttctctc gttaatgcac
    68041 tccctaataa attgtcaata ctcagttgct ttctatcact aaaatactta tccaataatg
    68101 attcctctat atcttcctga tatgccaaat ttccttcatg cattatatat tttacatcaa
    68161 aaccttcttt atttaatact tttcccacca agatacttct atgacatctt ataggttctt
    68221 gcatagctcc taataaaact atcctataac ccatttgaca accctttttt aatctttcta
    68281 ttccgtttaa aaaaatatct tcttttgcta ctttctcaaa atctgcataa ccttcttgcg
    68341 tatatacatc tttattagtt cttttagctc caaattcttt tcccatgtat atatataaaa
    68401 atccggaatt tctaagagat tcgttaaatg cctctttatt gtattgaata ttatatttag
    68461 aatatggagt ttctctaatg tcaactacac aatttatgtc atattttttt atcatattaa
    68521 taagcttatc atatggataa tttgaatgtc ctattgcgaa tatttccata taaacaccct
    68581 cctattcttt gaaattagta tctatatatg tagatacccg atttacttaa aattaaataa
    68641 agtattactt taaataccca atatcttttt ttcttgatat tgtatatttt tttactttat
    68701 atccttaaaa aaatatacaa ctttatatat aaaacatcaa tatttatata tattttgtat
    68761 attaaataca attatttata aagtctttaa taaaaattta taaatagagc atctttagaa
    68821 aactattata ataaaaaaat aagaggctgt ctaaaaatat agataagcct tttttcataa
    68881 tcgtaattat aaaaatatac ttgatttcat atgaaaaaga gtgtctcata aactaaaatg
    68941 tttactttga gacaccacct tttttattct tatttatact ttgtagacat attataacat
    69001 gcgtttcact ggtatctgaa cttctgtcaa ccagtcttct tcactctctt tattccatat
    69061 accatctata taagattctc taggatttcc aaccacttta tatttattgt cctctatcca
    69121 tttaaatgca tctgcgtaag tttttcctaa tgttgaatat ggaccattgt gtaatataca
    69181 aactgcattt tcaactgcat ctaattcttt aaattttaat atatccgtat cttcctttaa
    69241 atcatttata gcttgacaca tttcaacatc catatcagtc tctctatatt caccatcatg
    69301 atatatatta aaacaataat caggaactgc acatgtacac cctgttttca tcatttcttc
    69361 agccattaca tttggaaata gattaaaaag ttcatcatac ccctttaaca cttttctcat
    69421 agaagcaact ttaacttttg gtaaagactt aataattaca tcattcatat tgacttctcc
    69481 tttcaaattc ataaggtaat tacgtagttt aattatttta tattcttcac ttttaattac
    69541 atccaacatt tctttttctt tattcattaa aatattttca acttcttcag gattttctac
    69601 agcttttttt atctcagcta atgataaacc catttgtttt aaagttatta tctgatgtaa
    69661 tttaggtaat tgctctgttg tataatacct atattttgta aattcatcta catattctgg
    69721 ttttaacaac cctatatctt cataatacct taatgtcttt gtagttattt tatttatttt
    69781 agaaaacatt cctatagaaa acatctcatc acctgcgcat tagatttgat taatttaagt
    69841 ttaaactttc cccttaggtt aaagtcaata caaaataaat tataattgta ttaattcttc
    69901 aattctatct ccactcaata ccaaaatatc ccctgttttt ataatggttg aacctttagg
    69961 tattaaaacc tgttcctttc tttttatcat aactattaat atatcgtctg gtatattaga
    70021 atctattata ctcttattag cccatttatt accctcatca acatttactt cgataagttt
    70081 agagctaatt tctccatcat aatcattaaa tgtttttaat acaggtgtat tatcatcaac
    70141 taaatccaac tttctggcta cagttggtat caatgaacct tgtattccta ctgaaagcaa
    70201 cgctataaaa aatattatat ggaatatgtc attctctatg gctactcctt gagtaacagc
    70261 ataaattgca aaaactactg aagccgcacc tctaagacct acccacgata tgaataattt
    70321 ttctttattt gagaatttaa attttgctag aactataaat gttgctaatg gtcttgcaat
    70381 aactatcatg aatatagata tggccattgc tataccaaat acatttggta acttagaagg
    70441 gaaagataac aatcctaaca taaagaataa cattatttgc ataatccatg aaattccatc
    70501 aaagaaatga accaaacttt ttttaagagg tatcctacta tttcctataa taatacctga
    70561 aatgtaaaca cttaaatatc catttcctcc aagatactcg ctaaatgcat aagaaagtat
    70621 tgcaatagct gttataaata tagtataaaa tccttctatc tcgaagtttg aatgtcttaa
    70681 aatataaaca gataattttg ctagtataaa tcctatagct aacccaaaag ctatttgttt
    70741 tattaccatt ggtgcaataa gttctacccc agaattattc atcaatgtca aaagaattag
    70801 tgtcaacata tacgctattg ggtcattact tccactttca acttctaata atgatgcaag
    70861 tgaacccttt aagtttagtt tttgagaacg caacacagca aacacagatg cagcatctgt
    70921 tgaagctgca attgccccaa ttaataaacc ttcaagtaaa ctagttccta ttaccatgtg
    70981 gcaaaacata cctgtaacgc cagccgtaat tattacaccc agtgaagaca ttaatataga
    71041 aggtatagca acaggtttag ccatattcca gtttgttcca aaccctccaa aaaacattat
    71101 aaatattagt ccaatagaac ataattgttt tgtcagttca tagttatcaa aatagattcc
    71161 taccatccca tcagacccaa ataacatccc tagtaagata aaaatcaata atattggtac
    71221 tccaaattta tacaatacct tgctagaagt tatacaaatc aatagtacta acccacttat
    71281 aatcattaat tctgtcatag catcaactcc atttcatata aattttgtag attaatttac
    71341 atctacaatt ttattactta ttcaaatata acatgacata aattttataa gttatggtac
    71401 ataaagttca acaaaaattt cacaatacat taaaatgtga gtgttatact taaatttata
    71461 tatttgtttt aattatattc atttaatatt tataatttga attttttttt attaatattt
    71521 cattttttag ttgattgttt aatatatttc attttttata gtaattttat atataactac
    71581 gaaatataaa gtaattagat aagtaacaag aaactaacat gtaatgttag gtactctaga
    71641 tatgaaatct taaaactttt aaatattgaa atatttcttt atatatatta ttgtatattt
    71701 cttataaatt attgtcaatt tattttttct taaaaataaa ataattgcat aatttatttc
    71761 aaattatgca atttataaaa tttattccca aaactctttt actgcttcga ttatctcact
    71821 ataaggcaat aaagtcgctt cgattattga tttatttgtc ttttctaaat aatacttaat
    71881 catataatat ccacaagcat atcctgcaca ataaggcaac cctactggaa aatatccttg
    71941 cattttagct atatcatcac cataaagata agatgttata ttttgaaatc cagtttcttt
    72001 taaagcactt tttattattg gctttatata agtatttaat gtttcgatat ctgttctact
    72061 gacccaaggt cctaacattt cctctccaaa catccatgtt gcaaaatttt ctgcaagacc
    72121 ttcatttatc atcatttctt ctaatgttac attattattc cactctataa actgaaatct
    72181 aatattgtga ttacattcat gtgctattaa tactggtaat ctattgatag tatattcatt
    72241 aggaaccaat gatagaaata tatatccagg aatcccacca tcaccccagt atccatcact
    72301 taatattgta taaggactat ttggattcgc caataatatt gaatatttat agtccttaat
    72361 gtttaaatca tacccttctt ttataaaagc atttatagag ttttctatgg tttctttaca
    72421 agtggcccaa attttatcag cagataacac atttatattc tttttttgct tttcatcaat
    72481 atccttaggc gataaaaccc ctaacatttc acttgctata attacatcat atccaccttt
    72541 ctgtctagca actattggaa cattcataca cttccactta aattcaaaag gcttcatcaa
    72601 ttcatatctg tatatatctt cttttttgtt tattggtgca tccattatct tcttgtatat
    72661 tttatctgag cgaatttcta taatattcat atttaccatc tcctttaaga caaagtatat
    72721 acaattacgt agcgtcaatg tcaatataca ttttttataa tgtcacctta atctttttat
    72781 tatattttat cctgtaaacc ttccgtacat ataacatttt tttaaattaa taaatttgta
    72841 taatataata ataaaaaatt atatacttca agttttccct atgatacaat ttactaaatc
    72901 ataatttaga ttatcaggtg caactataaa ttattctata tcaaggagga tatattggtc
    72961 atgctaactc catatttaat atttaatggt acttgtgaaa aagcatttaa tttttatgct
    73021 gaggctttcg gaggaggaaa aactatattt gcgcgattag acagcaatcc aaacaatcct
    73081 attatgcacg caagtgttac tttcacaaaa tacgaaggtt gtataatggg tgcggataca
    73141 gacaagcctg ttgtaatttc tggcatggcg atttgtgttg ttctaccatc tcgagaagcg
    73201 atagaagaaa tatctgtaaa acttgccgaa ggtggtacac ttgtacaaga atttttacca
    73261 cacccaccac cacatcaaaa tgatggcgct gctgaagtac ttgataggta tgggtatact
    73321 tggtatttaa gtacatagtt aaaataaaaa aactacatct aataatcata atatagaaca
    73381 gataaatttc aatttaatag tgtagtaaaa aagtcgtgtc ctaaaactgt cacgactttt
    73441 atttgtataa aaatttaagt aaatattttt gcgaataagt gagaagtata actttaaatt
    73501 aatttcatat gtagtattgg aaatgggtta ccttgtccat ctatttcaga cctatcaaac
    73561 actttaaatc ctaagtgaat ataaaatcct acagcttttt tattctgctc atttacatca
    73621 acatatttta cattgtattt atctatagca tattttatta attttttacc aataccattt
    73681 cctctatatt tatcttctat aaagagcatc tcaattttat ctttatctat tcctataaag
    73741 ccctttatta tatcattatc ttttatacaa actatatttt ctacttcttt aagtccaatt
    73801 tcaactaatg gtatcaaaga ttcaatatct ttttctgtta aaaaatcatg cgttgctctt
    73861 actgatgatt cccagacttg caacatttcg tcatattctg ttgaatttat ttgtttcatt
    73921 tcaagaatta ttccagattt cataaaaatt tcctccctat atcactttta attgcataac
    73981 acttttttat acaaaactta gaaaggacta cgaaggttaa atatcatagt cctcattaag
    74041 tttaaatatt atctattata tattattata ctataatcta gcaaattcac tacaataatt
    74101 cacatcagct tatactaaag gtgcttctat ttgagtagta aaaaggaatt tatgacaatg
    74161 accatcatta acagtagttt ctccacatat taagtgaatg tgtttatcag ttccaggtat
    74221 tctaattgct ggccctgttg taacacatat cttatggaaa tggtcaagga aatctacatt
    74281 atcatttatt ttatgaacat gatttgtacc tccatttatt ggtatagctt caccagtaac
    74341 ccctgctgca cggtggttat gtctatcctc acattcttct gctaacttaa cactttctga
    74401 atattcatga acatgtgtca tttcctcata atcattatag cacttgttgc acttattgta
    74461 tttataatca tcatacacat aatctctttc acatttataa ttttgataac tcatttttat
    74521 atctctccct atattatatt aagaaattct tgtaaagaat ctctaatgta taatatgaat
    74581 taaagtcaaa aaagttcata ttttgtaaaa ttatgtatta atttaattat ttttcccagt
    74641 atttagggcg tattagtgaa gctggtaact tcgtactaga atctcctttt gcagtattta
    74701 cttgtaattg tgttaaaaat atactatttt caagattagc acctctaata tcacaatctc
    74761 ttaagtctgc tcctattaaa tttgccccac tcaaatctgt atttcttaaa tttgctgcta
    74821 ttagaaatct acctcttaaa tctgctccta ttagatttat ttttctaagg tctgctccta
    74881 ttaaatctat atttttactt aattttttca tgtttttaag agtagaagtc ttgataaatg
    74941 atttaacctt tcccatcaca gactcactcg cttgtgataa taataaatta acctttgttc
    75001 tatgtgatat gatatccaaa ttaattatct gttctgggcc catattagtt atcttttcag
    75061 tttcttcaat tattaaatca atttttgatt tgattgtatc tgatatattt aatacagatg
    75121 cttctttaag ataccataac atttcatgta attgtctcat aattaaaaac acttcagaca
    75181 tttgatttgt tagttctgat gattgcatcc agtctatccc cttatatgtt acttgtgcta
    75241 ctttttgacc tgaaccaaaa caatcatatg cagtacaccc tttaaaacct cgcttcataa
    75301 gactattatg tacagaacat ttaaaatctg gttgtaaatt aatacagggt tttcctgatt
    75361 ccttatcgat aggaaatcca tctgaagcag aaaaataaag agctacacag caaagtccaa
    75421 agcacttctt acagtcaatc tttagctcct caaataactt attatcatat atatttttat
    75481 gtatatctat catatttttt ctcctcttaa actttatttt taatattata ttatctataa
    75541 ctaaatgata atcaagtccc ttatttaaca gttcttattc ttaattataa tttaaggtat
    75601 tatttattcc aatagcatac ataagtttct ttatacttgt aacaatacct ttatactaag
    75661 acttatttta aatgtagcac tgtaataata aattgtttat atactcataa tgtatttgat
    75721 aaattgtaaa tctttataga agttgaaatt tttaatgatt ttagaatcaa gatataataa
    75781 taaatacaat ttataaaatc agaaatatat aaattaacta tacaaaccta aataacatag
    75841 catttaaatt tacaatttca gtataaatag tacaaagtat attagtttaa ataagattgg
    75901 cttatttgta gaggagagaa tattttggtg ttcaataaaa tttatattta ataaaaccat
    75961 aagaaaatat aaagataaat aaacaaactt ttattactta atagattctt atggttttat
    76021 actgtactga aaaacaataa acactacagc ttatttataa tattacgctt ttttaacaac
    76081 agaagacttt agcttcatag ctccaaaacc atctatctta cattctatat catgtccatc
    76141 tgatgagtca tggattaaac ggatattttt cacttttgtt ccaatcttta tagatgatga
    76201 acttcctttt actttaaggt ctctaattac tgtaacagaa tctccatcat ttaatacatt
    76261 tccatttaca tctttgataa tatttgaatc ttcttcagct cccaatccta atgcccactc
    76321 atgagagcat tctggacaaa ctaaaagagt tccatcttca taagtatatt ctgaattaca
    76381 tttcgggcaa tttggtaaat tttccatctt tatatgtcct ccatttgtta tttttagatt
    76441 tcttattata taaaatttct tttgagcctt tatgatatca tattatactt atatttacaa
    76501 actactaatt tacttaatgt ttaaattcta ttcgtattat tattaaactt gatttagctg
    76561 taatctcttt cttatattta ttatagttga tattattaca attttataac tctatctgcc
    76621 tgctccgata actctaaatc atgagttaca aatacgatag ttttaccatt cttatttaga
    76681 cttttaagta tatcaaatac tatgtctcta ttttttttat ctaaattacc tgtaggttca
    76741 tctgcaaata ttacttcaca ttcttttaat attactcttg ctaatgctac cctttgttgt
    76801 tctcctccac tcaattcgta tatctttttt ttattgtatt ttctaagacc tacagactca
    76861 agtgcgtaat ttattttttc attatggttg atattttttt gatactttaa agcaattttc
    76921 aagttatttt caacattttc attctcaatt aaagcataat tttgaaatag atagccataa
    76981 aaatcccttt gtaaaattct tatctgttta ctatttggat tttttatatt atttattata
    77041 atatcaccag aattaggttt ttctaataat cccattatat taagtaaagt tgtcttacct
    77101 gaaccactat ttcctgttat cgctacaaac tcgcccttag aaatttccag gttaaatttg
    77161 tctattatag atttatcttt aaatttttta gatatattta ttaatgaaat catcttttta
    77221 atgttctcct tttataattt tattaaatga actatttgag ataatcttgt ctaatgcaat
    77281 agatacaatt acttctataa ctaatattag aagtccaaat aagataatat tattacttaa
    77341 atctactctt gttgatataa tgcctattgg aataatgttt gttaatatta atgaaactat
    77401 taacaacata cttctagctg tagttgaata accaaatatt tttttaatat ataacttata
    77461 tttatttctt tcatagtagc tagctactat attgtaggta atcattaagt ttgatattgc
    77521 tattattatt atagtaaaaa tttcactatt caaatatttt tctagtttat ttatttctaa
    77581 accatactca ttataaacag catgtaaact ttggatatgc gcttctacac cttgagcttc
    77641 aataatgtta cttatatctg caagggcatc taatttctta gaattaaaat atacacatct
    77701 agatatataa gaaagataaa aagaatcatc aatattatct atgtcaacta ttgctattgg
    77761 gtcatcaatg agattcctat tgtcatccat aacaagggag ttataagtaa aatagctttg
    77821 attattatct acatatatta tattaacatt taaatctgac ttctttgttt tatttaactc
    77881 tctatttaac tctttattgt acatattttc tacttctatt ttttcaaaat aaaataattc
    77941 tctaaactct tttttaatct cattttcatg tacttgtaac tttttaggaa ctaataaatt
    78001 tatagtctta tcgccataat cgattagatt aaatatttct ttgccatttg agtaaatagg
    78061 gttaacttta agatagtttt tatttatttt tatattttta ccatattgac ttacttctgg
    78121 gtttttaccc tttgaattta tttcatacat gtaacttcca tcttcaagtt tttcaaaatt
    78181 agttgaatct attaagaaag catctttttc ttctaccaaa tttttataga aacctttaat
    78241 cttggcattt ttaattactt cttcctttcc taaagattgt tcgcctgtat ctttaagagt
    78301 aagattataa acattttttg ctttatccca ctcagataga tttcctaact gagtttgtag
    78361 catattataa tttaaaatac agttatttat ggataatata agaaatgata caaatacaat
    78421 tttcaatgtg aaatgcatta tatttacaaa accataagat ttttttccat ttagagatag
    78481 cacatattta gaacttctac tattaaaacc aactattaat atagatatca aaatatttat
    78541 caaaatacat ataatcgaaa acatagcaaa gtataagcat gctctaacac ctatatttaa
    78601 ttttaaaata tagattatat atattaataa tgctgtgaca gatgataaaa tcataattct
    78661 aagtatattt tttataactc tagcaattat atctagctta gagtatccat ttaatcttaa
    78721 aatagaagcc tctctactca cactaattga ataatgtatt attgtagcca agaaacaaag
    78781 gataattagt attaaatctc taattattga aggatttaag tataaatttg agttaacata
    78841 tctatcatgt aatcttgcta caaaaatact tctgtctaca tttagttctc ttaatatttt
    78901 atttattgta tcttcatttt gagttgaaat atacaagatt cctgattctc caacttcact
    78961 tattttacca aaatccctaa ttaaaattga tatgtcttta ctcatagttg agaatttacc
    79021 tacttgatta ctattattag tgtttatatt actaataaat tcatttgaat tagtattagg
    79081 aaattttcct gattttaact ttatattgtt attcaaactt gtatcagtcg tatatataga
    79141 taatttttca ttattattaa aaacatactt tgatatagtc acattatttt catctgcaat
    79201 atctttaatc cacttactat aatttttatt taacttttta taatctttaa acattacaga
    79261 tatacttgtt gtatcgttat ataaaatatt attaatttca ttatctttaa ctatatttag
    79321 acctaataaa gatactatta atagttcaat tgtaaataat acatatatta tctttttcaa
    79381 ttatagctcc ctcctaattg tttttattct aaaagcaaaa tacattttac tttagttaaa
    79441 gtataatgct ttgtgccttt tctaaacaac tactatattg tcacattcta aatggcaagt
    79501 gtctatttcg tcacaaagat aaaaatagcc ttaaagcagt taatttttta taatcaactg
    79561 ttttaaggct attttttatt tttagcaaac aatattttaa tagtggtata aaattagtat
    79621 aattcattaa tatagattct agtcttttca gtaagcaact aaaataatat cttatttaaa
    79681 acgaaattta atttaagtcc aatataaact ttactttacc attaaatcgt gctagtacat
    79741 aggtatgctt cttttttatt ccatataatg gatatcttat gaatatctat agaatcaaga
    79801 taataaggtt gtccaatttg gaatttagaa tatgtatttt taaatttttt atttacatat
    79861 aataaaaaat tattttcttt attaatcaca caaatacact ggtcaatatt atctaaaata
    79921 ttctggtatt gttgaatctg ttgattaagt ttattatttt ttttacgttg taaaaacatt
    79981 gatataattt gagaaatcaa tgataatgta cttatttcct cttgtgacca tagacgtagt
    80041 cctgtgcatt catcaaatcc aacaaatcca ctgaaaactc tatcttcttt atatgcacat
    80101 tgaagtgtag agtggatacc ttgactagaa aacaattctt ctagtttagg acttaatgta
    80161 tggatatctc gacaataaaa aactaattca tcctcaaaaa gcttttcata atcctcatag
    80221 tcttgataat tgctgttttg caaataagcc atttgagaag agattccttc attacaccat
    80281 tcataagtat tagaagtata tctaccatct tctgtatttt caaaaatata aacacgactt
    80341 acatcaaact gtttcccaac aacctcaagt atcatattaa tcgcctggtc tatatcatca
    80401 gtctgataaa gcatacggaa tatataacgt gtaagattat caggatattc agcgtattgt
    80461 ttttctgaat caataactgt accaagagaa gaacaatcaa attcttctaa ttctttaaaa
    80521 taatcttggt tgtagattac ataattattt tttcccatat tttttgcttg atacagggct
    80581 ttatcagctc ttgcatatat ttccttgaat gtagtaccat cctttggata tatagctatt
    80641 cctatgctac aagttacttt tagaaaactt ttttctttct gaaatagatg acggaacata
    80701 tacaatagtt cttctgcttt cttttctgca tctttaactg aggaaatatt cttcataaaa
    80761 attgtaaact catctccacc tattcttcca acaacatcac tgtcacgcat tatttttttc
    80821 atacctgatg ccatctcagt aagtactata tctccaatca tatgcccttc tgtatcatta
    80881 atctgtttaa aattatctgt atcaatcata aacagtgcac ccataacatt taaatttttt
    80941 tcaaaatatt tcttaatctg cctttcagtc tcagcacgat tataaattcc tgttaatgca
    81001 tctttctctg atatatgctg taatttctca atctgttttc tttcctttgt tatgtcaata
    81061 cctatactat aaaaagatgg tattccatcc caactgtctt ccccactgat ataacacaat
    81121 gtaacagtcc atatacgttc ttcccttgaa cgtgtatata tttttgcttc aaatacaaca
    81181 ttatccccag actccttcaa atcttgtgcc agtttcttac tacgtttata atcttcagaa
    81241 aataaatatc cacattgatt attaagttcc tctgcaaact gttcctttgt atattcaatc
    81301 atattcaaaa atatatcatt acaccaaagt atagtaagat aatctcttgc atctaatcta
    81361 accattcctg ctggaatagt tttcaaaatt gattctcttt cctgatcttt ttttgctaat
    81421 ttatattcag cactatacat atcataagat aattcaatac gaactcttcg cccttgccaa
    81481 ttcaacatac ggtctttaat tataaatgtt cgtttcagtt ttttattata aaattcccat
    81541 tcatatatgt catctttttt taaatacgaa tttgtacaaa acggacatgg cgaagttcta
    81601 ccttgaatta cctcataaca ttttcttcca ataagttcat ttgctgatgc ctgtaaagta
    81661 ttgcatgagt gcttatttaa gtatagtaat tcatatgtat ccatatcgct aatataaaca
    81721 ttcccagcat actctgacat catccattta aaattctctg tactctcttt ttccatatca
    81781 gatagttctt cttgctttat ttttaactca ttaatttttg aatacaatat atagaccatt
    81841 gatttctcat tatcttgtga ttcaattaat ataccagtca ttattaccca aacagggtct
    81901 ccattatttg ctgaaatgca aatttgatat tctatactct tttcgccatg atgataagcc
    81961 tctaaaaaat gatttttcat agattcaaaa tgataaagat tctgttcata ataatctttt
    82021 aaactagaaa atttaactaa aaattcttct tctgtatatc ctaataattg atagaatgat
    82081 gtatttcccc atattattgt aaatgaatca tctaaaaaat gtttactgac cccaatactc
    82141 atagatttta gaatatcctc tgatataact tcattctttg ttgcttgttc ttttttacac
    82201 attcgatgta acctaatgtc ttctttcatt gttttaatta tcctcctatc tttagactca
    82261 cttttaattc actctgcttt ttaatataat gataaaagtg aatcttcaac gtgtataaat
    82321 tgatttcatt tacaattatt ttttgtttga aattgaattt tcacacacac ttgctaagat
    82381 tctccctcta aaacttttaa tttagtaatt tttttgatgc cctattcacc atttaatatc
    82441 ttaattatcg attcttgttc acttaaatct gtatttaact tttcccctaa aaacacatta
    82501 ttttctcata tttactaaaa atcgccttct tttaatgaaa ttatatcata acttaagttt
    82561 taaatcattt ttttccagat agaaaaatta agataaaatt actgaaatta tatgtaatat
    82621 aatagaaatg taaactgttt taaatttgaa taatattaaa aaggctgtat catagtaatt
    82681 ataagatact atgatacagc cctatgttaa atttttctta tatttttaat gatttcacga
    82741 atctttttag catttttagc aatatcttca acagaacctt tagttaataa accaccaaat
    82801 ccacatacat caactccatt ttctaaccat atatgtaggt tttcaatatt aatccctcca
    82861 cttgctaaaa ctggcatatc aggtattggt gtcttaaata cctttactag tttaggtcca
    82921 tagaaatctg atattgggaa agcttttata aaagttgctc ctaaacttag tgcgtctact
    82981 gcctcagtca atgatgtaca tcctggagca taaggaatct gatatctatt gcaaatcttc
    83041 gctacacctt cattataatt tggtgcaata ataaattgag ctccatgtaa tatagcatga
    83101 cgagctgttt cactatccaa aactgttcct gctcccacac aaagtgtttc accatacttt
    83161 ttattaagcc cttgaattat ttctccagca ttatttaggg tataactcat ttctataact
    83221 gttataccac cttttataca tccttcagca atttcacatg cacggttaag attttcttct
    83281 cttacaattg caagagcccc acattctgac attcttttgg ttatattcat ctttttcata
    83341 ttatcacctc tatactcatc aaaccacttt acttattcat taattttagt catgttttat
    83401 aatatatata ttaattatat accagtgtaa tttccctatt tatattatct attctcacta
    83461 cttttattaa gtattgtcct ataattttca actactcgtt taatttcttc aagtacttcc
    83521 ccagttggtt cagttacagg aagtcgtgca gttccaacat taattccatt caagacaata
    83581 gttttcttca taacagatgg aattgttcca agtttcagta tacgtcgaag ttcttctata
    83641 ctactttgag ctttttgagc ttcttccaaa tcccctttca taaagttttc atagatagag
    83701 ataccaatct ctgtgaggaa gtttgttgtt gctgcaacag ctccttgact accagctttt
    83761 agactatcca gaataagtga atctgagcct gaaaacacac taaaattctc attcttcgtt
    83821 gcttcaatat aagctttcat gttgtcaagt ttaccactac tatccttaat tccaacaata
    83881 ttctttatct ttgataattc acgtactgac tctggttcaa tattaattcc agtcttacct
    83941 ggcatattat acattataat aggtaaatta actgaattag caatagtttt gtaatgtaag
    84001 attaattcct gttgtgttgg tgtaacaaag tatggtgtaa taatagataa tgcacttgct
    84061 ccaatcgctt ccattctctt agataaatct acaacttcac gagttgaatt accccctgtt
    84121 ccaacaaaaa caggtacacg attatttgta tgattaataa caatctttgc aaattcaact
    84181 ttttcatcat ctgttaatac atgacattca ccattagtgc ccaaaataaa taatccataa
    84241 attccctttt caatcaaata atcaattaat tgacatgttg cttgtgaatt aatattttga
    84301 ttttcatcaa atggtgttat cattgcacat ataatccctt tatatttcat aaaattatat
    84361 cccctctcta atagactttc caagacttcc tgctggatgc cacttcaaat actgctgtgt
    84421 attaagacct ttagcatatt gtaatacaac acttaatgat tgtaatatta ttgtttcagc
    84481 taaaattgaa gcacgaggag ctttattgag acaatctcct tcctgcttaa cacctgcaaa
    84541 caggaatata tcagaaatat tttttaaaaa tgaactctca ttaccactta caccaattat
    84601 ctttgctcca tttactttta gagtcttaag agttgctttt aactcttgag tttcaccact
    84661 atttgatatt gcaataacaa catctccttc aactacttga ccacttgacc catgtactgc
    84721 ttctgtacca tgcaatatat atgctgacgt tccagtagat gaaagcaatg atgaaatata
    84781 tcccgataca tgtcctggtt tgccaatacc agtcacatgt acacgtccgt gatttttttc
    84841 agcttcaaga attaattcgc atgctttatt tatagatgtc tcatctattg aggcaataaa
    84901 ttctgacaat tcattagata tattatctaa aaattcagat aatgtatttt ccataagatg
    84961 tatcctcctt gaaatcatag taactatgac tatactttta tataatttag tttaaatagg
    85021 ttttataaat tgtaaaatat tatgtaatat cgaaccaact acgttgtaat caatattagg
    85081 gaaagttgct ccttctatac caagagtccc ataaactgga tatagtataa ctggcaaaaa
    85141 tgcaagtaat aaccccacaa caaatgaccc agcaatagcc cctctccatc ctcctgaagt
    85201 attgccaaat attgcagctg tacctcctga gaagaaacat atgtgagcag ctggaataat
    85261 tactacagga aatatactag gaaatgatgc cataatagca attgctaata gaccagcagc
    85321 atatgctgat ataaacccaa taataactgc atttggtgca tatggaaata cggttggaac
    85381 atctagcgca ggacgtgaac ctggaatata cttttctgaa atgattacaa atgctgcagt
    85441 tatttcagct aagaacatac gaacacctga catcaatatt gacatacctg ccacaaatgt
    85501 aaatgcctct ataagcggaa aaaccaacca atgtgttgaa ccagcaattt cttgagtaaa
    85561 tgcttgacca gcttttaatg ttgcaatata aaataagatt aacataacta tggatagacc
    85621 cattaagaag tctctgaata ttgataacca cttaggaaat tctatagtct ctgttgtatc
    85681 atctttatgt tttgaaaata aacgcccaat ataacctgat aaaccataac caatcatgtt
    85741 aaagtgacca atagcttgtt cgtcgccacc tgttaattca cgcataaatg gttgacagaa
    85801 ttgaggtagt gcagcagaca taaaccctaa gatagttcca cctattaaaa tagtgattgt
    85861 attatcaaat ccatgtgctt tcataattaa aactaataca caagaaaaga acaaactatg
    85921 acctgttgta aagaaaatat tcttaaactt tgtaatacgt gcaaatacta aatttaatat
    85981 gaatccaaga attaatgtac atgaaactgc aaaaccatat gtaccttgtg caagtgctgt
    86041 agctgcttct ggtgaagcta taacaccagt aattccaaag ccatgttgga acagtttatt
    86101 gaaattttga agtgctcctg tcatagcaga ggcaccaata ccaaatatca aaaaaccgat
    86161 aagtgttttt gaagagcctg taaatacttc aacagctgat ttcttttgaa gaatcaatcc
    86221 tatacatgca actacgccaa gcaaaacagc aggtgtactc agcaaactaa taataaactc
    86281 cataaatatt cctccttatc atcttaaatt tatccctctt ttgaagcaag gaatttttct
    86341 agtgctgtct ttatttcatt acggtcaaca atattgtgaa tcccaattat atcaaacttc
    86401 aaatttttat tttttaattc ttcagcaaca tcaattaatg tttctacagc atctccattg
    86461 aatccattta gtgaatccaa tgaaccatgc tctacttcaa ttggaaagtt attttcctta
    86521 ataatttgtt gagtctttat ttttaacatt aaacttgagc caactcctgc tctacatgcg
    86581 attaaaattt tatacataat taaatcctcc tttataattc gtgtgttttt ataaaatcaa
    86641 taatttcttt agcttcttta gcactatcta aaaccttaaa aaactcatct tcttccaata
    86701 gttcaactag ctcagacata gcacgtaaat ggctattatt gtctattgca cttagacaaa
    86761 atacatattt tacagggtcg ttttcgttat tcccaaactc aataggacta tctaaagtag
    86821 caatgcctat tgcaatctct tttgacccag cttctggtct agcatgtgga agtgcaacat
    86881 gttttgtaat tactatgtat ggtccagatg cttttgctga gttaatcata gcatctacat
    86941 acccttcagt tactttgtta ttttcaacta atacagaagc tgactgtcta atagcttcct
    87001 cccaattctt agcttttacc tttattttta ctagtgtttc attagtaatc tcacttagca
    87061 taggcccctc tccttcctta gatgtaaaat tctctatctg tgtaaaataa gctaatagct
    87121 cacttgaaag aatactttca gaggttacat ttgcatattt ttttattata tccataacct
    87181 catctatttt aggttgtctt aaaaaaatat cacctaattg aatatacact tcacgtgtaa
    87241 tcttatattt ttcttttgtg gtcataacag ggcttacttt aattactggt acatctgttt
    87301 ttaaaccctc tgcgttataa ttagtagtaa atacaatatc tacaggttca cttatatttt
    87361 ctaatccaac tgattccgac attggtataa agtgtaagtc aggaaataag tttgtaagtt
    87421 ctgcatgtaa aatagctgaa ctaccaacgc catttgaaca aactattaat gctattcttt
    87481 ttctaaaacc atcaaattct tttttatttg aaaaaagtgt tgcaaagtgc attgtaagat
    87541 atgctaactc ttcttcctga atttcttctc caaataatcc gcaaaactct ttcattgcat
    87601 tacttacaat tctataaact aatttatatt cttcttttac tttttcacaa atcggattat
    87661 agataggtaa tttaaataaa agtctatagt aggcaggtct aaaatgagaa tataattgtt
    87721 taaatatttt ttcttggctt atatagtaaa ctccacttaa atatccaaac tttgtcatca
    87781 ttttatttac aatttttgaa attacatcct tatcttctgt atcttcttca taatttccta
    87841 ctgatatacc taaaatccaa gcactaatat acattatatt gtgaggcttt attttatctt
    87901 cactcccata tacttctaat aattccttag caaatttata ctccttcatt gaactcataa
    87961 ctgaaatatt aggaatatct acattttcct gagtaactat tctagttgaa tacatccttg
    88021 cctttagaaa gataaatata tatataaatt ctattaatct atcttcaaca aaagtaattt
    88081 catatttttt tattagcttt aatataattt ttttagcctc ttcaaaacta tctaaattat
    88141 attctttaat aaaaatatca aatacccttg aacttttctc attagacaaa gtttctataa
    88201 tatttttaat aagcactctc ctaatttcca tctcattgcc aactatgtaa tatccattta
    88261 tacgattgtt cttaacttta atgttcttct tttcaagctt tggtatcaaa tccttgaaat
    88321 caagatttac agtagaccta cttactttta tagaatttat aaaatgatta attgaaatat
    88381 cctccatgtt aataaaaagc attaaataca tatataaaag tctttctgtc ttactaaaat
    88441 aataagtatt cttagaatag tttttttcta aaatttcttt aattgctttt tttgtttctt
    88501 ttctaacgat aatatcttta tcagctctta aacatataag tggtacattt tttactttaa
    88561 gcatgtcatt gattttattt attctataag taatttgtct ctttgatgaa ttagactcct
    88621 cttgtaatcc attagttgta atcaatgtgc tatttaataa aatctggaga attgatacaa
    88681 tttctttgtc cactaccatt aacccctact ttcttattaa gattagtctt catattatca
    88741 ttggattctt tcatcacctc cacaatactt attttatttg agaattttat cgttttcaat
    88801 ttcatttaag tataactttt gttttagatt gatacaaaaa ttaaacttct ctaaaataga
    88861 tactataata taactgtaga ttttataaat taaaaaaagt tccttatgtg aagaaaccaa
    88921 gaaaaattta tttaaagaat caaaacgata ctaattatgc ataaattacc ataaataaaa
    88981 ggcacattaa tttaaaataa aattaatgtg ccttatttat aattctaata tattaaattt
    89041 attttttaac ttgtagttta atatcctttt tcttcaatta attcatataa ataaagtatt
    89101 taataataaa tgttccttat aattttaata ttttaaacca agaaagttaa agtttctctc
    89161 atataataag ttgatactta tctatttcat tcttttaagt gtttcatcta atgaaataca
    89221 ctctgcatac cttccattcc agataaatct attgtaatat ttattaatta aaattaatta
    89281 ataaggagaa ttatttctct catttgtgat atgattctca cttatattat taaagtattt
    89341 gtgttgtgtt tttagaaaat cttttatata aggcatttcc tggatttata gctaccaata
    89401 caattgcaac tattaaatat aacattgcat agtaatttat aagctctatt aaatctccat
    89461 taattatccc tattaaaaaa ttaaatagtt gatgtattac aataggtatt atcaaagttt
    89521 tatttagatt ataaaaagtt gtcattataa tactgattga tataattgca atcataaaaa
    89581 atataatata ttttattaaa tcaagtcctt tgaatcctgt tgtaaaccat attggtaaat
    89641 gccacatccc ccaccaaaaa cctactatta tggatgcttt taaaggagaa tgtcttttct
    89701 gaagatgatt ttgaacaaat cctctccaac ctaattcctc acctaatgat cctgcaaata
    89761 aattttttaa aaataaatat ataaatgctc cccatgatga aactgtaaag ttaggcatta
    89821 ttccatgatt tttagatgct aatataaata taactactac agctattagg acttgtatac
    89881 taattattat agatactgtt gaaaatttaa gtttatttct aaatctatct tttacgtgta
    89941 ctaaaaattt cttatctgga taaatttttt taaataatat cataaatgca aaagtggatg
    90001 accacgctga tatacacaac gcaatgtcag atatcactgt tggaagtttt aacattatag
    90061 tcactactac caataaaaaa agtggtaaaa aaattatatt tgttagaata ataaaactgg
    90121 ctataggcct ttttaatgat ttctctgttc tcataagtaa tcctcatttc aaattaatat
    90181 ttaattgcta tataagttat aactgcttat atcatgagtt taaacctatg agtaagtccc
    90241 aggtcaatgc ttttatatta ttttataggt gcataaatct ctaaaaatat acgctcaatc
    90301 ccttcttcat aagtagtaag caatatatta acatagacta ttccaagtaa ttcacattca
    90361 ttttctattg ctatttctct taatctgtct tccactttat tatcaatatt ttctcctcca
    90421 gttgaccatc tgccatcttc aataatagta taaatacaat tgggatgaga tagaacttca
    90481 ccttctatga ttttgttgta gtcatctact tcccttacaa ttataaattt ttcttctatt
    90541 ataccttctt cattaaaatt tattactctt cttaaatcag ttaatgtaac tgcttttttt
    90601 aagttgtttg tattctcttt tagggcttca tattcctcat agttagtaac atgttttatt
    90661 ttacctttta cttccaaagg cttcatttct tttattgtgt attttccaaa atatgttttt
    90721 attttgtcac aatcttcttt gactaactga acctttttta agagaagctt tttatattct
    90781 atctctttta gtatgatttg ttccttctct tctagtaaga gttctaaatt gtttatactc
    90841 ttactttttc ttatttcttg aatcttttta atttctatat caatttctct ataaaagttt
    90901 attgttgcaa tatcatagat atcaacctga ttatatattc tatatccatt ttcatcattt
    90961 ttcttaggat ttactaatcc tttgtcctca taaaatttta gtgtatctct agatattcct
    91021 aaaaatttag atacttgtcc aattgtatac attatattct cctattatta gataaattct
    91081 ttatgctcat taaacgtatt tctattaaca attacaaaat cacctaaact ttgaagtatc
    91141 aaagtcagca tagtatttac aacctttgga attactcttt ttatttcata atccaagtgt
    91201 aaacttgtta atatgatacg ttataaagac tatattgtct acatatttct aacaatgatt
    91261 ctttcacttt aagatgttct taaacatatt taacttttat ttttaaaaat ttcctataca
    91321 taaaaatatt cctttcatga taacagtttt attatttcaa ctatctgcta ccataaaagg
    91381 aatatcttaa tctttaaaca cattctaaat gctcttttaa caaatattat caaattattc
    91441 taattctatt gtttcatatt tattagtctt agttttatat aaatttaaat ataaaactat
    91501 atattcacct acttttaagg atacaataag tcttcttcta ccagtaagag taaatgcctc
    91561 ctctacttat cacaaactat aatttttatc tcattggtat atatccacga tactgtgagt
    91621 atgcatccat agttgctata tcacctaaga atactgatgc gatattgaat tgtggtttta
    91681 aatatgggaa ctcctcttct tgtgcccatt ctggtttttt aataaacgac tttgtctctt
    91741 caaccacagc tttataccat tcttcttccc cttcaaacca tagttctgat acacggtcaa
    91801 aagcagttgc tccataatta atcattattt tactactgac aaaacgatta acatagcaac
    91861 agtttgtaaa gtatggcact acctcatcat agaaccattt ttctccttct tctttagaga
    91921 taccatctgg atacttaatc ataaattgcc aacgatagtt tggtccatct tgtacagtac
    91981 gtccttttcc tctaaagtct tcttcccagt ttattggaac aaaggcaaat ataaatggtg
    92041 gacatccatt atctccacct actgcacgtc ctgcatctcc actttctaca ttttcatgaa
    92101 cccttttatt ttctacatct ggtatacacc cttgccaacg tagaacatcc ataggcatat
    92161 attctgtcat aattctattt gccatctcag gcatatgttc atctacaagc caataatgtt
    92221 ctgttagttg catcttacgt gcaccaaaac gctcaccttc atttggtgta ggatatgctt
    92281 gataaaaggc atatttagta caatatggtc caaaagtgct aatactatct ggaatatggt
    92341 gacgatataa ccagtccatt agcttaggtc tatattcttc cttggcaagt cctacatata
    92401 ttaaacttct cattatttta aattcaaaac ccatagccat tctcctataa tcaaagtata
    92461 ttcacatgct ttcaatttcc ctttttccta tctttactca aaatatatat tgtaaacaaa
    92521 tctacacctg cacccacgta ccatactcct actgccatag ctacagcaat ttgaatacaa
    92581 atatcttgta aattaataat attttcacct gtcataacag ttagacctat agcccaacca
    92641 caaagccatg atggtaggaa aattattttt tcaaataagg atgcaattac aactgcaaaa
    92701 aaacctaata tgctaagtgt taaaaataat tctaggtttt gattgaaatt catatatccc
    92761 ataattaaaa tggctaacac tgcccataaa tctccacacc aaaaaccaaa cattattttt
    92821 aatccatctt tttgtttatt accattagtt acatataatc ctgcacagat tagtgctaca
    92881 gctccagttt ttattcctat ataaggtgct aatactgccc ataaaggagg tagtaaagca
    92941 atccccatag acagtgttaa tatttctttt ttctttctat ccatttccta tattgtaatt
    93001 agtagcttcc ctagcttgcc ttatctccaa tagcttaatt gctatttgat ttacaatcat
    93061 agatactgca aaataactta aatatagtgg tataaatata acaataaatg ctggagttaa
    93121 tctaaccttg taatatgtaa gtaccaaaaa aataactgct aaaataactt caatttgttt
    93181 aaaacttggc ttttcattca tacaataagc ctcctataac atctaacatc ccttaaaaaa
    93241 gagtcttagt attttaatta ttatcctaat gaaactccag cttgcttttc tttagttaat
    93301 ggctctataa aattataaga tgtttttctt tctttaaatt cttgtgtttt acgaacttct
    93361 gcataatgac cttccatttt cttaatatca tcaccatgta taaacttacc tggtaaagta
    93421 tcatgagcat gacctaattg ctcttctgga aaactaaata tagtttttcc acttatagta
    93481 tctaactctc caactatacc acatagagca caaattgcct ttttagtacc tggctcaagg
    93541 tagaataatc tattgtggca atgtggacat acaccttctt ctccttgata tgaagctttt
    93601 tcaaaatctt ttgctgcttc aactatattt aaaccaattt gatgaacttg aacaagcctt
    93661 gtatcatcca ttactaattc ctttgcccat gggaaccaag cattatctat aactttccac
    93721 attggtatga gagctagcat agcatgttca cattgaactc ttgtacccca gtcagaacct
    93781 cctattccca taaatgatat tactttatca ttaagcattc ttgaatctgg aatttttcct
    93841 cctataactt ctgcaacttt tgttcctata atgttatttc ctctatctgc tctgggtcca
    93901 aaacggtcca ttatagtatg gaataatcct gatgcccctt cttcaaaaat agggtctgaa
    93961 actactatac catctgcatc tttcattttg tcaagcaacc attcaaaatc atcttttaat
    94021 acacacatac tacctttccc agataataaa gttttaacac acgcacaaca tccagtacaa
    94081 tgtttaatgt taatagatga catttgaata aattctactt cagcccctgc ttctttggca
    94141 cctttaagtg caactttaca cattgtgtca ttatttccat tttttgttcc aaaagaaata
    94201 cctagtattt tcattttcaa ctctccctct ttagtattta tttaatcttc tttcattttt
    94261 aatatataga atccatcatc taaagcatct atgatgatgt agcctctatc atcaacgata
    94321 agatcttctg ttactgccaa gcgtggtcct gggaatcctg ggaaataaga ttcttctggt
    94381 gttttatttg gatttggtgg tataaaatat gctagctctt tgatataata tgggtctgat
    94441 acatcataaa cccttagccc tgcatggaaa taacagcaat atactctatc tcctctttgc
    94501 tctaaccatg gcttattatc cattggttca tgaagattat gtggaccaaa tggccctggt
    94561 tttcctaatc ctgcaacatt aaagttagga taagggaaat cttttggaac ttcaggatat
    94621 ggaaattgag caattaatgt tggttttgtt gggtcactaa catcaaccat atgtatatta
    94681 ttcatagctt gaacatctgt aatgttatct ggtttaaaga actggaatct ttctccctca
    94741 ttttgaacaa cgactaaatc tcttcctggc aatggtaatg ctgtatgagt tcttgcacct
    94801 gcaagtctac tagaaaatgc aggcgtaaat ggcaattcac ctaagcatct tggtcttgtt
    94861 aaatcttcaa catctaatac aactaaacca gctcctccat aaccacaata tgcttttccg
    94921 tctcttacaa atggaggtcc atgaagccat cctttatcca taaattctgg gcaatgaggt
    94981 gctcctgcat caaaagttct atttggatat ccatctgcat attggtctgg tctccaccat
    95041 ttacctattt ccactggatt agtaggattt attatatcta tgaccctata aatcagacct
    95101 tcaaagccaa cacaatcact tgataaatgt acatatcttc caccattgta catgaatcta
    95161 tgaacaccca ttacatgctt taagccacaa tcccaatatc ctaaaaactt aggatttaaa
    95221 gggtcttctt ttaaactgta tattctaatt cctgcttcac acttaatatt tgctaattta
    95281 gcttggtcaa caagtgctcc tggtccactt ccacaactca ttgctactat cattaaatca
    95341 tctgctattt gaattttggg agttgttgtt gtaggatact ctttagggtc taacatttga
    95401 aaatgtttta taaattgtgg attataaggg tctgtaatat cgctaatcat tactccattt
    95461 tttttatttc ctccaaaaca gcatccatat aaatagtatt tttcatctct tttgtacaga
    95521 gccatttgaa acattccaca agttccatct aagttattaa aggaacaaac ttcaagattt
    95581 ttaatatatc cgttatttcc gttgcctttt gcataaaatt tatcttccat tttttctccc
    95641 ttcttatttt aaagtattat caattgatat actttcattt tatgagacaa acttacttaa
    95701 atccaatatc gttttcattg gaatatataa gttattctta ttaataaatt tataaaatct
    95761 aatgtaaaga tatacttaaa acatatattt ttatacaaat attttctaat attctttaaa
    95821 agtaaatttt cttatactat aataagcttt aattatagat aaataaggtt tacaaacaat
    95881 caagtttaaa taggggtgat tatttgaata ctaaacaatt agaatatttt atatctgtag
    95941 cagaaaatct aagttttacc aaaacagcag aaaaatttta tatttctcaa actgctgtta
    96001 cacagcaaat aaaagcttta gaagaacaaa taaatgtaac tctatttaca agaagtaaac
    96061 gtcatgttga actaacacca gctggaaaag tttttttatc tgaggcacgt actataataa
    96121 aaaatatcaa tgatgctatt gcaaaaacac aacaatttgc acatggtttt tttggaactt
    96181 tgagcattgg aaccttaata ggatatgaaa aaaacaaact tcaacaatat ttaaaagaat
    96241 tttctaatac ataccctaat atatctatgg atatttgtac taatgaaata accgaacttt
    96301 taaacttagt aaaaaataat tctatggacc tcgcttttgt tattaatcca gaaaatcaac
    96361 cattaaaaga ttttgaatat aaaactgtag aaagatattc tttggtagct cttttacctc
    96421 ctggtcatcc actttacaat gaggattcta tcgatttaat tgaattacaa catgataaat
    96481 ttatttttgt aaaggaaaca ggggatgagt atggacaaaa atctatgata cagaatagat
    96541 atcgtgaagc agggtttgta cctaatgtgg tacaacgttc aaataatctt aatactattg
    96601 aatcattggt atcttctaac atgggaatat ccattttacc ttcattttgt gttacagata
    96661 caatgataga acgtgatatt gcaatagtac ctataaaaga agtagaaaat agaattgaag
    96721 ttgtagttgt atggaataaa aaaaatacaa atccagcatt agaaaagttc atttctataa
    96781 tataaaatta atcaatatta acgataaaaa tagcattaac cattttttct atagttaatg
    96841 ctattttcta ctattttatt atttaacttc taatttaata tttataatcg ttaaaaataa
    96901 ctctgtttaa caaatataag caagtcaaaa atgtgtctaa aaaagataaa aattttatta
    96961 tatacaaatg tattatctca atatatctat tttttcattg ttcatcagtc taagtacatg
    97021 acctgtgctt actaaagaat tatccccata agttgtatga gctaacaccg aactagcaac
    97081 cccaaactca actatatctt cactcttcat attttccaaa tatgaatata taattcctgc
    97141 cacatatcca tccccagcac caactctgtc atatatttct aacttatact ccctactttc
    97201 aaaataacca tcatcatttg atatatatcc ctttataaat ctattattca tatcatcaaa
    97261 tcttctcata gttccagcta caatatctat atcatactct tttttaatca attctgaact
    97321 agattttata tttagactat ctatattaag tatcttattt atatctctat aactagcaaa
    97381 tagcccatga caatatggta gtattttctt ataatcattt actaaatcat cataagtcct
    97441 ttctggattt aatgattgtc taaaattaaa atcaaagaat acttttatcc ccttttcata
    97501 agattttcta gctagttcta aagcaatctc tttaactgaa tctgtaagtt gcatagcaat
    97561 accacaaata tggactatat ccatttcttc taaacattta tcaatatcat aatcttgtaa
    97621 tttactctca caaaatgaac tatttaacct attcaaataa gtcacttcag aaggtctttc
    97681 tccataccca ttttcaagaa aatacactcc tatatgattc cctccatacg tgataaagtc
    97741 atcttttact ccaagctttc ttatatttgc acttgatgct ttacctacat tattattagg
    97801 caactttgtc aacatatagg tattgtatcc aaagttttta agtccagata atatatttaa
    97861 tcccgtgcct gtaattatat aatttagttc attggtttgt gttaagaact tgtagtcagg
    97921 tactgaaagt ctcatcatta tttcaccaaa agctaatata ttcataaatc tatcccaata
    97981 attctttcat tattttataa agtactccta tatcttccac tttcgtttca cctgtttctt
    98041 tatcaattat tgatgtataa acatgaggta taactttttc tacaccagca tcaagtgcaa
    98101 tttgaactat ctctttgaag ttatctaagt ctatacctcc tgttggttct aaataaaaat
    98161 tatgctttgc acaagctttt gcaacttcta tatattcatc ctttgtttta agccctccca
    98221 ttggaaaaaa cttaattgag cttcctccca tatctttcat catagctatt gctgtttcta
    98281 taggaactat accatctttt tcttttgaac ttaatggacc tgtggatatt tttacaaatc
    98341 ctggtttacc agttggagaa actaatccat ttattatact atcattttga ccaagcaatg
    98401 ctctagacgt agccacacct gtaaacactt gatttatatg ttgtggctga agttctttag
    98461 aaatctgaga taccatattt gactgatttg ggtctccagc tccaagcccc acagatattg
    98521 cattatctat ttcctttgag tattttttca tatcttcaat agctacttct acagtgctgt
    98581 aattctttga tagtactcct atcaatacat gcccgtcaca agcatcatat acttctttag
    98641 cattttttat gcttcctgca agaacattta aacaaactct atttttataa tattgtggta
    98701 tacaattcat atttatcctc tccattggta aaatttaatt tattaaatca ttataatgtc
    98761 acttactcta cactctaact ttctactata ttttttatcc tattataaat agtatctaaa
    98821 tcacttccag ttacacttct tatatcaatc tcaatcttgc cttcattagc cttatagtct
    98881 ctagtgtata tagctatctc tccacttcta agttcattta taatttgttg tgttgactta
    98941 tttattatat cttcattaaa gtcaatttct ccacgaagta tttctctacc tgctgaatcc
    99001 ctagttatac tagcactcac tccctttata gtatttatct tgtctataaa tggatttagc
    99061 ttgtcctcca tttcttttaa agttacttta tcattactta tatatctctc aattgcacat
    99121 gttagaccta caatattttc ttttcctatt ttcatagctc ttcctatacc ctttgattga
    99181 agctttacat tatctatgta ttttttctta cctattacta accctgagct aggaccctct
    99241 atagccttag caccactgta tatcactagg tctgctccca attcataata tacatttaaa
    99301 tcttcttctg ctgctgcatc tactatcaaa ggtaaattat attctttagc aacttgtact
    99361 gcatctaata cacttagcat actcttttga acacaatgat gagatttaat atacataatt
    99421 gctgctgtat tttcatttat ctctcttatt atatgttcct tgttacacat attagcataa
    99481 ccggcctcaa caacttctcc tcctccaagt cttatcatta cttctactgg aactccataa
    99541 tcaacattat gtccctttgg aattattatt tcccttttaa cttgtttctt aggattattt
    99601 acattgtaaa ctagactcat atcatctttt gctatcattg ctcccacact ctgtgcaatc
    99661 ccagcagatg cactagaaac tattagtgca ctttcacacc ctaataaatt tgctatatat
    99721 tcacctgttt tatttataag ttcttctatt ataaagaaat ttttacaccc ttcacctatt
    99781 gcttcaataa cttccttatc tactgttgat actcctagta tagtcatttt gcctgaagca
    99841 tttataacac gtcttacaga gtatttttca aatatactac tcatacaata gtttctccct
    99901 tctactcatt ctctcctata gacttaccta tatttaaata ttctccattg actactactg
    99961 ctcttggctt tatagacgta cttgtgatta ctgacttatt caaagaatct tgaagttctt
   100021 tttcttcatt aaccacatca aatatagtta aatcagcatc atatccttct tttattaaac
   100081 ctttattttt taaacttatt gcatctgctg catttttagt aactttatct attatatctt
   100141 caagtgaata gcccatatat ataaactttt ccattgttgt agatagatta tacactggac
   100201 catttattct atttttaata tatatatctg tacttatagt gtctggaaaa attcctgcat
   100261 ccttagattt cattgcaata tccatactaa aactttcggt tccatgacct acatcaagga
   100321 ttatacctct ttctctagct tctatgattt cttttttaac ctcattgcct ctaagtattc
   100381 catttggctt tccattatat atatgggtta atatatctcc tttttccata tagtcaaata
   100441 tatcctctat cgttggagga gaactcccaa agtgaaccat cataggtaga ttaagttcat
   100501 tttttattct tttagctact tttaaaggtt caacatcatt tgaaattaca acacttttac
   100561 tcattctagc tttgattcca acaacaaaat ctttgtattt tttaactgct cttttaagtt
   100621 catattcatc aatattcatc atacttgaaa gttcatcttg agatgttatt ccctgcttag
   100681 caatatttat taaagcatat acatttgttt tatatttttt agtatcttca taaaatttac
   100741 ctatatctaa agctcctgtt gttcctgcat ctactacagt agtaacaccg ctttttattc
   100801 caacctcatc tggataatcc ttataaaggt ctagtctttc gtagcagtgc gtatgtatat
   100861 ctatccaacc agcactaata aatttttctc catctaggtt tataatttga tttgcctgat
   100921 acttagaatc atctatctga ttttttactt ctattatttt atcgtctaat atagctatat
   100981 caattatact tttatctact gtttttccac cttttattaa tatgtctatc ttcactttac
   101041 tctccctcta aaataagttt aaatttactc caaggttcaa taaagtctaa aagcattatt
   101101 tcgtcttcct ttattctacc taccttattt tttctttcat ctgcacaatc ttgaagtatc
   101161 aactgtaatt cccctttata ctttccaaag tcatcattac caatcactac atctcctctt
   101221 ttaaagatgg tcgtattatc atgcttaagg aaattttctt tagcatattt ttttcttact
   101281 tctgtagacc ttgctacttg gttggttata tcccctcttc taaagtgttg ctcatttgcc
   101341 attattgtct tttctacttc agaagttttt tcctcagtta ctacattaaa tacaacttga
   101401 tatttattta cttcagacat tctttttaat tcatcttcac ttgcatatgc attccctaca
   101461 attacatcat caatcaatcc tgttgcgaat aagtgcttag ttgctgtagc aatatctaag
   101521 tttctatgca tttcaagcgt acacaatcca tcatttatat tccaaggtcc gattgttgca
   101581 tattttgaat taacaaaagc agcagttctt attccatact ttttaaatct atttgaacat
   101641 cttacaaaaa aatcatatgg caagcctgta cccctttgag gataaaaatt gtgacaacca
   101701 tatatattat ttacatttgg cttgtaagta attatattat ccaagtatgc tacatcatta
   101761 ctcatattta gttccacttt taaatcatat ggattgaaag aaatcatagc ttctttactt
   101821 ccatcatatc catagtcaag ccttattcca ctagcattta actcactaaa gaatgttaaa
   101881 tcatcataag atatttgtaa tatatcaaat atgtttggag ctatatcaag gattacttca
   101941 aatcctaatt ctcttgcata ggttataatt tctttaaaat gttttttaac ttcttcctta
   102001 ggtcttgtaa ttgaaagcat gcacataaat attcttttaa atccgtattt tgaagccatt
   102061 tttatatatg ccttatcatc ttccatgtta ctatgctctg gatatactga tattcctaat
   102121 cttctttcca tctttctcct cctcaaatta cattatttaa aatatataaa attaaaggca
   102181 aaggtcattc ctcctacctt tacccttaat aacttataag ttttttctat attttatata
   102241 gtacaaaacc tctatatcta tgtattttta taaattttca ctcatttctt cttgttctct
   102301 ttgtaattgt tgtttttcaa aaactttgaa gaatggataa taaacagcaa atgatatcac
   102361 aaagttgatt aatactaaga tacctgctag tatactccag ttagtactca ttactgctgc
   102421 tattggtgct ggcattgcaa atggtaatct tgctaccatc ataggtataa cccctgtaat
   102481 agtaagaaca tatgatagaa ttgtcattat tataggtcca attataaatg gtatccctag
   102541 tattggattc ataactattg gtgctccaaa tattataggt tcatttatgt tgaataaccc
   102601 tggtaaaaat cctaatctac ctaaactttt tagatattgt gacttagaaa acataaacat
   102661 tacaactaat gcaagagtag cccctgctcc ccctatccat acataccact gtaaaaattg
   102721 ttctgtaaat atgtttggca ttgcatgagc tgatactcct tctgtgaatg cagttatatt
   102781 ttctgctata gacatgtccc atataggtct tattactggc cccattatag ctggaccatg
   102841 tattccaagt acccagaata aagttattag gaatactgtc agtaacccac cacctaaact
   102901 atttcctgat aagaatcctt ttaaaggtga taacatagcg cttagtgcaa cacttatatc
   102961 aaatcctaaa atatgtctta ttacccagaa taacattaaa attactgctg tcggtaataa
   103021 tgcagtaaat gaatttgaaa cctctactgg aactcctgct ggcatcttaa ttgtaatatt
   103081 cttttccttc ataaaacgat atatttcaac tgtaattaat gatgttacga tagctccaaa
   103141 taatgatggc gaattaagtt ttgccatatc catccatcta ccagcttcta taactccacc
   103201 tactggttca actacttgag ttggaactat tgtagaaact aaaaatgcca taactgcaag
   103261 cataccaaca cctgttgtat ctaaatcgta gcttttagca agtgatgatg ctatcccaaa
   103321 agtagcatat agagataaaa atcctacagt atatctaaat ggtatatcta atattgcttt
   103381 aaatggagct ataaaatcca tataagcatc aataggtatg tttaataata ttgtgaaaaa
   103441 tgaccccact attgttagtg gtaatgttgc tattatacct gctcttacag ctctcatatg
   103501 tctctgatta cttatcttcg ctgctacagg cataatcttg cgctctaaaa aacttgcgaa
   103561 tttttccata gttatccccc tgtattattg atattatcct ttatttataa tgcaataacg
   103621 atttcataac ataaactaat ttttatgtaa ttgataatat cacttgttta ttaaaaatat
   103681 tataacatta taatgtttgg ttgtaaacat tataatgtta taatattttt tatttttaca
   103741 actaaacaaa aatcctgagc atattatcat ttcaataaac tcaggattct tattatattt
   103801 cgtatttaat tacatagttt tgtacttctg tattatatct tgcaaatgat agctcaacta
   103861 tattatcatt ctcatcatag gtctttcttt ttcttcctaa taatatgtct ttagctagat
   103921 ttaaagcctt tgatacctct agttctgatt cttctataaa aaattcatct tcaaatctag
   103981 ttatatttat atttctccta tataagtaca tatataaaga attttcatta ttaaaacttt
   104041 caacagttag attttcatca aaaggaatat aatgagtaaa aaatatatat ggcttactat
   104101 ctaaataata cattctagta atcttgctac atttttctcc aaatatacta aatacttgtg
   104161 aatttgtatc atttattatt ttttcaattg aaatagtctc cttaaataac ttatgacctt
   104221 tagataaaag tatacttgaa aaagactctg cttttgatag cttattaaaa aggctattac
   104281 ttattacttt tgtccctttt ccactttttt tctctacata tccttctgat tctaatatct
   104341 caatagcttt tctaatagta attttactga ctccaaactc ttgctctaac tccctttctg
   104401 ttggaatatt ttcatcaatt ttatattcgt tatttaatat tttttgcttt aatatatcta
   104461 caacttgtat atataatggt tgatttctta acatgattca cctcttaaat tatatgttat
   104521 aatattataa catataatct tatattatta ataataaata tttattaact ttaaactaaa
   104581 tataaaaaga gtcctcaaaa taatcctaat gtattactca ctaaatattg aatcaataat
   104641 ctaacaatta gtgtgctaca cataatgtat cttttaagaa ctctcttaat ttattctctt
   104701 taatttttat ttatcttgta atttcaaatg taaatcaacg atttcctcag ctaactgtta
   104761 aaaattcatg ccattcatta ggtggtcctg tgcatgtata agtatgacac ttatttcagt
   104821 cctgtttcca ctagcttcgt tttgtattaa ttctgtttga tatctatgtg ctttatttat
   104881 aacttcccta gactctttta ataattcttt tgctttttct atatttccat tcttagcctc
   104941 ttttattgct tcaaaagcta atcctttacc ttcacctgca taacctatta tattaaaaga
   105001 tatttctata atcttttcat ccatcctttg attctcccaa tttatatatt aaaaatacat
   105061 tataatttat attacttagt gttgttaagt tctatcgctc tatttaaaac agcttctcca
   105121 ttaactgttc catagtgcat catatttata acttctactg gtatattata tggcttagca
   105181 atttcttgag ccttaggtaa tacatatcta acttgtggtc ctagtaataa tacatcacat
   105241 ttttctattt cattttgtat agttgattct ggtattgccc aaatttgcga ctctatacca
   105301 ttttctttag ctgcactttc cattttagta actaataaac ttgtagacat tcctgctgaa
   105361 caggccaaca ttatttttat catatatttt cctccaaatt tttattaaca accatataaa
   105421 cattataatg ttataatatt ttatttaatt ctaccttaaa tgcaatatac tttcaatact
   105481 tttttgttat tttaatatta ttaagttgca aactaacaaa aaccgtatca tttatttatg
   105541 atacggttct ccattattta tcctataagc cctataaatc tgttctaaca atatcaatct
   105601 catcatctga tgaggaaaag tcatcctaga aaaagataac ctataatcag cccttcctaa
   105661 aacctcatca gaaagcccta gagaacctcc tattataaaa cagagactac tattacctct
   105721 aactgctaaa tcactcatag tcttagcaag ttcttcagag gataaaccct tcccatcaat
   105781 agccaaggct ataacataac tattatgctt tatcttccct aaaattttct ttccttcttt
   105841 gtcttttata atttccattt ccttaacact caaattctct ggagcttttt catcatccaa
   105901 ctctataatt tctaacttac aatacttaga aagccttttc ttgaactcat caatacctaa
   105961 ttttaaatat ttttctttaa ttttacctac tactactata cttatattca tatatttctc
   106021 ctaaacttaa ttttattaca aatctatgca ttactagaat ttacaagctc ttataaaatt
   106081 atatctctct ttcttgattt gcatattcta caaactcttc aaaaggtatt gctttgctat
   106141 aataatatcc ttgatatatt tcacatccta aaccatataa cttatccctt tggtctatat
   106201 tttcaacata ctcaacaact atatcaaaat ctaaattttt tgaaagattt acaatagtca
   106261 ttataatttc actacttctt ttatttgtaa gtatctcttt aactaatgaa ccatccaatt
   106321 taactatatc aaagttatta ttttgaagat atataagaga gctatgcccc atcccaaaat
   106381 catccataat taactttatt cccaagttat gtatcgcatt gatacgttca ataattattt
   106441 gtgaacctga taatgcaatt tgctctgtta tttctatacc taacatatta ggatttatat
   106501 cattactact aatgatattt tttatttgct ctggtaactt agggtcatca agttggtctg
   106561 gagatatatt tacagagaac ttaacaggat ttctcaatag cttttcactc ttctttaaat
   106621 caatacatgc tttattaata atatactctc caagctcatc taagaaccct tcttctttag
   106681 ccaaaattat aactagtggt ggataaatga accctcctat tgaatgtttc catctaagta
   106741 atccctctgc tcccacaaca tttccattat aattgacttg tggttgataa aaaagctcta
   106801 tttctcctct tttcatagca aacttcaagt ctgatgccaa catttttgaa attgaaccta
   106861 ttttaccatt atggtttaga agattaggct gttcacctgt taattcatac ctttttaata
   106921 agtttgttaa attttctata ttatttttaa acatatatgt atatctattt tgcgacattt
   106981 ttataaacgg aatataaatc ataacaccaa cacataaatt aaatacttgc aacaaactac
   107041 ctcttattga acctgtagac atatatccac ttaaaaatat aggtgaggtc cattctacag
   107101 ctgaaactgt acatggtaca atacctgtag acatagccac ataacttgta atggttaaga
   107161 ttataggagt aattacaaaa ggtacaaaca taatatagtt aaaaacaatt ggtatcccga
   107221 aaactagcat ctcattgata ttaaaaagag ctggtattga agcaatttta gctaactttc
   107281 ttacatttat acgtttttca ctaagaaaaa ttgcaattac taaacatagt aaagagccac
   107341 atcctcccaa taaaaccatt gtatcaaaaa aggtcttagt aaaaatttct gttggtaatt
   107401 gattattatt aactaaattt atgttaattg ccatactatt ttcaaataaa ttttttgcga
   107461 cggtatctaa tacattacta ccatgaatcc caaaaaacca cataaagtgc attaaaaaaa
   107521 taaacaacag agcactcata aggtttgttc ccattttatt aaaaacattt gaaaataaat
   107581 tataaaatat atcttgaaag tttgaactgc caattagact tatcattatc actctaaaaa
   107641 tagaaaacaa aaatactact attatgaaag gaactatagc cgaaactacc atattaaagt
   107701 ctgcatcagc cccttctgta tgaaacttta cacttgtaac aaaagattct gtaagtttta
   107761 caaacaatac agaagatgtc atagaaacaa ttatagatgt aaataaccac tttgttttaa
   107821 atatttctat ataagaatta agctcattac catgtgaaaa tactaaaaaa gagcacattg
   107881 caactatagg aacaagtact gtatacttgc tcccatatat ttttccataa ctatagctta
   107941 ttgttaataa tattattaat gaaataattc ctaaagtaga atcatttata aagttaagaa
   108001 tatttgtaac ctctccatta aacaagcctg ataaatattc ttgataagcc tttattggaa
   108061 gattcaaaat tacaagagca gttgaaccag tcataatagc aggtatcgct aaaatcatac
   108121 cctgctttat agagtataaa attttattat cctcaacatt ttcaaaattt ctctttagca
   108181 aagttattca cctctacttc atctcataaa cattagaaac atcatttcgt gatagtacat
   108241 ctagttttac atcttgtcca actactatat catttgatgc taatactcct tttgaagtct
   108301 catacgctaa ctcaggaaaa ttattttctt tacttaaatg tgctaataat atagattctg
   108361 taccttcatt aataagttca acgcagaaat tagctgcatc ttcattggat aaatgaccag
   108421 tacttgacat tactcttttc tttaaagcat atgtatatga acccatcata agcatattag
   108481 ggtcataatt tgattccaat actactaatt tagatttata tagatgtttt tttatatttt
   108541 gagttataca tcctatatca gtagctatag acattttttc atcactctct gtataaaaat
   108601 tatatccaac tgggtcagac gcatcatgtt ctattgaaaa aggtcttact atgatatcac
   108661 ctaatgagta ggttttatca ttttcaaata ctttcatatt tttatctttg atgtcaccta
   108721 atttgtcctt catagaacac catgttttta tattagcaaa tactggtata tcaaactttc
   108781 ttgataatat acctgctcct tttatatggt caacatgctc atgtgttata aatattcctt
   108841 ttaatttatc tgcatctaca ccaatgtctt taagacctgt agttattctc ttgccactta
   108901 atcctgcatc tactagtata ttagtatttt tataccctat atagtggcaa ttaccactac
   108961 taccactccc tactgaacaa tactttagca ttccttcacc tctttttctg ccttataaat
   109021 tatattatac caaaaaaaca gagtattaaa taaaatttaa tactctgcac aaaatttact
   109081 tacattcact gtttacttac attcacttat aatcttattt atatctacac ctttactatt
   109141 ccatagttcc acaaaagctc ttccattagc atttttatgc ttatatttat tatagtactc
   109201 atttaaagtc tcaaagaata ctttatctcc aacttctttt cttatttcat taaatgctat
   109261 tgcgcctttt gtataaacat tcaagctgta ttcagtagaa tttttatact catttgctgg
   109321 cttaaatata ttttcgctca aataactttt tgtctgtatc tccatagttt ttataagctt
   109381 gtttgccata tctttaccat acttttgttc aaaataaact attgtagaat attcagtaag
   109441 tgcttcatct aaccagggtt cacttatttc atcatttcca acagcagaat accaccattg
   109501 atgggctgtc tcatgggcaa taacatattc tagtaaaaat tcattttttt cattatataa
   109561 actttggtct atcataacaa gcatagggta ttccatcccc cctataaaaa agtcacttgc
   109621 tacaacagaa aattctttgt aaggatactt tccaaataat tcactaaata tatttattga
   109681 atcttttgcc acttcagttg cttttttaga aagcttttta tttaaattat atgtattgat
   109741 agctactccc tttgaatcta ctttgtttac atcaaatttg ctacttagta taaatgcaaa
   109801 atctctaacg ttttcagctt ctatttcata tagcattttc ttattatcat gtttatcatc
   109861 aataagtttt cctgtatgag caattttata tttatttgga atcaatagtt tcacatgaaa
   109921 atcgctagtc tcactataaa atgggtcgcc aatagtttca taactcttta aattccatcc
   109981 cctttcatca tttacacaag ctataggaaa ccaattagta acatttatag tattttctcc
   110041 atatccaaat cttccaattg aatttggtat ttttacgtta tattttatat ctaatgacat
   110101 tctttcattt ggttttaact ctttccctaa ttctatttct aatatgtcat ttttgtctcc
   110161 tttaatttta tactccattt tactattatt atttaatata ttctttatat ctatatatcc
   110221 ttcgttaaat ccattaggat aagcccttgt catttcactt ttttcaaaag gagcaaaatc
   110281 tttcttggaa aaagcattcg gatatatatg gaaatatatt ttatctatgt ttgattttgt
   110341 attatttatg tagtcaacat tctgattgca cattaacctc ttagtctcat catcaaatat
   110401 aacatccata ttatactgat ttatttttga attagttttt tctttgtatg tttctaaact
   110461 gtcatccttt tctataaagc aacctattat taataccata aatagaatcg ctactgataa
   110521 tgttcttctt actttttggt tgaattttat aaccaaaata tctcctcctt ttcaaaatga
   110581 atacttttag aaaatattta catgctaatc ttgtgacctt ttatttgttt acagacaaat
   110641 ataatataaa aaatgatata atttaatctg aggtgataaa atgtttttta aagaaagcaa
   110701 tgaaatagat ttaggtgaaa tcactattcc caatatcttt atagatatat ttatgccaat
   110761 ggcggacggg ttatacgtaa aagtttatct tttaggatat agacaagcat gtgatattac
   110821 ttctaatcct aagttcgaca ataattcaat agccaaaaac ctaaatatac cattgtctga
   110881 tgtgttatct gcttggaaat tctgggaaga aaagaagatt ataaaaatac atgacaatgg
   110941 agaatatgat aattttaatt attcaataga atttttagat ttaaaaaatt tctatattga
   111001 gaatatatta agcaataatt catctataaa atctaataca gataaagttg tatctacttc
   111061 tgaaaatcca agtattagaa aaatgtttaa ttctataaat aaaatagttg ggcgatatct
   111121 cgacccaagt gaaaagatga gtattatgga tataatgaat aaatacaata tgagccccga
   111181 tatgatactt tgcgcatatg aatacgtcaa agataaaact ggtacatcaa agcccgttaa
   111241 atacattgaa ggcattatta gaaattggta tgattcaaat ttatatacac caaaagatgt
   111301 tgaagaaagc tttttggtaa gaagtgaacg atatatttta tataaaacga ttttcaatga
   111361 attgggattt tcaagacaac catcaaaatc agaaaaagaa cttatggaca cctggtttga
   111421 taaatttaat atggatatag atttgataat aaatgcatgt tctaagtcta agaatatttc
   111481 aaacccaagt atatcttata taaatggtat aattaaaaat tggaatgaaa aaaatataaa
   111541 aaatttaaat gatttaaagc aaaaagagga agaacgtata gttaaggaga atattaataa
   111601 gaagcagatt aatactactc aaaacaacaa tacttacaaa aaaactaagt ttcataattt
   111661 caacgaaaca ttcactcagt atacctctga tgagctcgat gagattatta aaaaaagtca
   111721 aaaagaaaag tttaagtagg tgattaaatg aatgaggata aaataagaaa aatacttgct
   111781 aaatatgcta agagaagaga tgataatgaa ctcttattag aacatagaaa aaatgaggta
   111841 tataatagaa tcccggagat aaaatctata gatgatgaaa tttctaaaat aggtctcagt
   111901 ttagctaaga tagtactttt aaatcccaaa tctaaagatg aaattgtaaa gaagactaaa
   111961 gagaatatag agtctttaaa agtaaagaaa gaaagacttt tagctgaaag taacatacct
   112021 cttgattact tggaaataaa gtttcaatgt atttcttgta aagataaagg atttttacct
   112081 aatggagaaa aatgttcttg cctcaaacaa gaaattgtaa atgaagctta taaaatgtct
   112141 aatttagata ggattttaag tcaggaaaat ttttcgaatt ttaacttgaa tatattttct
   112201 cctaagaaag gctctgatgg tgaaatatct cctagagaaa atatgctaaa taatttaagt
   112261 atctgcgaaa attttgttca tgattttaag aaggataata gtgaaaatct actgttttat
   112321 ggttctactg gactaggaaa gacctatatg tgcaattgta ttgcaaagga attgttagat
   112381 aaaggcaatg ttgtaatcta tcaaacttct tttagaattt tagatattct tgaagattat
   112441 aaatttagaa gagacacaaa taatcaaata agtgaagata attataaaaa cttgtttgat
   112501 tgtgatttat taataataga tgaccttgga actgaactta ataattcttt tactagtgga
   112561 gaaatcttca atattgtaaa tacaagactt gttgctggta aaaaaatcat tatttcaacc
   112621 aacttaacac catctcaaat aggaaatact tacactcaaa gaactctctc tagaatatta
   112681 gataagttta ggattttaga atttactgga gatgatttga gatgggaaag atttaaataa
   112741 aatagccctt aaaaaacatt tttttatttt taaatagaga ggtaagagca aacttgcttc
   112801 tctgtttaaa acttatatca cataaattaa aacatacttt ttatttttct atttacatat
   112861 ctaatgtatc ttaatctaac aaatcattta cattcttagt agtctatatt tattgatact
   112921 ataaattaaa tttgctatat tacataatac tatgctagaa tgattctaaa ttttatattt
   112981 aaaactatca cattgcaagt aattcaaaat tttgttgtat gtttaatttc atttttaata
   113041 caataaaaat gaaattaaaa aaagatactt aaaagtatcc tgtaacatag aaaattatat
   113101 taatttgaat ttatgtactt tgtggagctg gtgataggaa tcgaacctac aacctgctga
   113161 ttacaagtca gctgctctac cgttgagcca caccagcata taatctagta tttatctcta
   113221 attcaaaatt tggtgggact aacagggctc gaacctgtga ccccctgctt gtaaggcagg
   113281 tgctctccca gctgagctat agtcccatac tggtgactcg taggggaatt gaacccctgt
   113341 taccgccgtg aaagggcggt gtcttaacct cttgaccaac gagccatatt ttggtgatct
   113401 atccgcgact cgaacgcggg acaccctgat taaaagtcag gtgctctacc gactgagcta
   113461 atagaccaca ttttttcgac ttttttcgtc gtttctttca ctcacaagtt atattatagc
   113521 gtctatataa tttttagtca atagtttttt ttactttttt tagaatataa ttaaaatcat
   113581 ctttagccat ttattttcaa caaaattctt tttaaaaaac ctatatgtat ctacataaat
   113641 tcaactttaa tttcagttag aatatgtata agtagcttta acttaataaa aaatcaatgt
   113701 aggtcaaata taaaagagca tctctaataa ctataaacat tatcttgaga tactcttctt
   113761 caactatttt aaattattta attgataaaa tattaagcaa atatatttct tcttattata
   113821 gtttgagctc tatttggacc aacagaaacc atatctacac ttactccaac tagctcttct
   113881 atttttgcta catatttctt tgcattctct ggaaggtcat caaagttatc tatttgagtt
   113941 atatcttcat tccatccatc taattcttca tatacaggtt cacattttgc taaatcatct
   114001 aatgaagctg ggaaatccgt tattatctta tcgcccattt tataagacgt acaaactttt
   114061 atcttatcaa atccagttaa tacatcaagt aacataaatg aaatactagt caatccatta
   114121 actctagctg catacttaac tataactgca tcaaaccacc cacatcttct tggtctacca
   114181 gtagttaccc caaattcatg tccttgttct cttatcttat ctccagtttc atttatttgc
   114241 tctgtaacaa acggtccttc tccaactctt gtagtatatg cttttactat accaacaacg
   114301 tcttttatca tatttggtcc tatacctgca ccaattgcaa atccaccaga tgttggatga
   114361 gaagatgtaa caaatggata agttcctaaa tctaaatcta ataaagtccc ttgtgctcct
   114421 tcaaacaata cttttttacc tgctcttact gcatcatata caataacaga cgtatctgcc
   114481 acatattttc ttatttgttc tgcatatcct agatattcgt tatatatagt ttcaaaatca
   114541 aatagttctt cttttccata tatattttta actatttcat ttttagcatc tatttgagct
   114601 tttaatttta tagcaaattt atctttatcc attaagtcac atattctaat accagatctc
   114661 tctgttttat ccatataaca aggtccaata cctttttttg ttgtacctat ctttaaatcg
   114721 cctctggctt cttctgacaa tgcatctagt tctttatgat atgggaatat gacatgtgct
   114781 ctatcactta tttttatatt ttctgtactt atattatccg ttttaaacat ttccaattct
   114841 tctaaaaatc ctttagggtc aaacactatt ccatttccga ttatattcac tgtatttgga
   114901 tttaaaactc cagatggaat tagatgtaat gcgtattttt taccttctac aactaatgta
   114961 tgtcctgcat tatttccacc ttgccctctt actactacat ctgcttgagt agcaagataa
   115021 tctataactt tacctttacc ttcatctccc cattgagaac caacaattgc aactgttttc
   115081 atgtaattca cctctatatt ttatatactc tcgaacactt tacttactta ttctatcaaa
   115141 cattcgtatt tttttcaact tttttagtat tctccaatat ttaacatata ttcttctatt
   115201 tttgaaaact cttctttctc tattatttct ttttcatatt ttataacttt ttccataaat
   115261 ttatccacat ctaaaagttt ttctaattta catatgttaa ttatgtttcc aaagtttgta
   115321 ttagtcatgt ttatatgata ctgattatcc acattattag cataaacaac aatagattct
   115381 cttaaattat tgtcaattac tctaaataag tttatttcat caagtacttt aattatattg
   115441 ggatatatat attttaagct tattttttcc atattattcc tcctaataat taatatttat
   115501 acacagataa agcaagccaa aagcttgctt tatctactta ttcacactta tcaacaggcc
   115561 atctgtggat agtgtggata gttttttagc taaatttcaa tgtttggaca tatttagtga
   115621 catgtatcca catttttcct gtagaaagaa aggacgttct gtggatattc gttagattat
   115681 aggtctctca acttatcccc aaatctttga acttcaccaa gccaaacaag ttccacagaa
   115741 ccagtttcac cgtgtctatt ttttgctatt attacttctc ctatattttt actctcagaa
   115801 tcagcatgat aatattcgtc cctgtataag aacataacta tatctgcatc ctgttctatt
   115861 gctccagact ctcttaaatc agataacata ggtctatggt ctgctctttg ttctggtgca
   115921 cgtgataact gagatagtgc tactacagga cagtttaatt cttttgctaa tatttttagt
   115981 gaccttgata tcttagatat ctcttgttgt ctgctttcat tattaccttc accttccata
   116041 agttgaagat aatcaataag cactaaatct agtccttttt ctatttttaa ctttctacac
   116101 tttgacctta gttctgatat ttttatacca ggagtatcat ctatgtgtat tttggcatct
   116161 gataatactg ccatagcatc tataattcta ggccaatcat tatcattaag tgttccagtc
   116221 tttatttttt ttaattctac actagattgt gaagataaca tacgttgtac taattgttcc
   116281 ttagacatct ctaaactaaa tacagctaca gaggcatcac cttttaaggc tgcattttga
   116341 accaagttta aagaaaaggc agttttaccc attgctggtc tagctgcaat taatattaaa
   116401 tcagtccttt gaagaccatt tatttttttg tttaaatctt taaaaccagt agttatacca
   116461 gtgacatcac tcttgttagt gtataatttt tctatcatat cataggcatc catcaaaact
   116521 aagtttatag atttaaaatc atcactagtt ttctcctgtg atatatcaaa tatactcttt
   116581 tcagcttgtt ctaaaacatc ttcaatctta gttgctccac tatatcctag atttattatt
   116641 tcattagaag cttttataag ctttctaagt acagactttt cttttactat atcagcatag
   116701 tattttacat ttgaagtcgt cggtactata gtagaaagac ttgtaatata actgattcct
   116761 ccaatatcat taagatgccc ttgttttctt agttcttctg ttaatgttat caagtctata
   116821 ggctcacctt tattacttaa agttatcata cattcatata ttattttgtg agcctcttta
   116881 tagaaatcat caggctttat agtttctgta accgttatta tagcatcttt atctagaagt
   116941 atagaaccca atattgattg ttctgattct acactatgag gaggaattct cgtcatatct
   117001 tccatcttaa tcacctctag ttattactgt ttttctttta catccactct tattttagta
   117061 gttacttttt gatgtatttt tatttctacg aaagttgaac ctaaagatct tattggttca
   117121 tctaataata tttttctttt atctacatct atgtcttttt gtttctttaa ttgctcagca
   117181 atttctttag aagttattga accaaataat cttccacctt ctcctgcttt tgaatatatt
   117241 tctatattaa tttcttccat ttgcttacct aataaaactg cttcttcata ctctttttgt
   117301 gcttttattt ctttagattt attcttttca tttaattctt ttattgctac actatctgct
   117361 tgcacagcca tctttttagg aaataagaaa tttcttgcat atccatcact tacttctttc
   117421 atttctccct ttttaccagt tccctttacg tcttttaata atataacttt catctattct
   117481 tcctcctcca aatactcctc tattatttta tttaccatct tataagcttc ttttagagaa
   117541 acatttttta actgtgctcc agctatatct atgtgtcccc cgcctcctaa tttttccata
   117601 agtacatgta catttatttg tcctaaagac ctcgcactta taaatatagt atcatctttt
   117661 tcacctaata caaaggaagc ttctacttct ttgatattta ataactcatc agcagtttga
   117721 gctattataa catttatact atctatctca gtacttgaat atgctaaaca tattctatta
   117781 ttaattattt tagtactttg aattatttca gcttttatta tgaaatcttt tacatcagaa
   117841 ttgaagaatt tctttacctc tatagtatct gctccaactt ttctaaggta agaagcagct
   117901 tcaaaagttc taacacctgt tttgaatgca aagtttttag tatctagact tatacctgct
   117961 aaaagccctt cagctgtaag tttatttatt gttacatctt catccatata ctgaactaac
   118021 tctgtaacca tttcacacgt tgaggataca tatatctcat ggaataaaag cactgcatca
   118081 tttataaact ctacacctct tctatgatgg tctataacta ctaccttctc tgatagcttt
   118141 aacagttctt cacattcagt ataatttggt ctatgagtat caactactac aactaatgta
   118201 tttttagtgc agttgtcaat agcttcctct tttccaataa acaacttttt atagtaatta
   118261 ttttcattta ttttatttat aaatatttct atagattcat ttacagattg taaaactatg
   118321 tttgcagttt tgttacagga tttacatata tcataaacac caactgctgc tcccatagca
   118381 tccatatcag gatatttatg tcccattata taaacctggt cactttgttg tataacctct
   118441 cttaaagcat gacctattaa tctggatttt actttggttt tcttttctac agctttagat
   118501 tttcctccat aaaacacaaa tttatctttt gtttttacaa cagcctggtc accacctcta
   118561 ccaagtgcta aatcgagagc acccgtagca agttttaggt tctcatttaa tgtatctcca
   118621 tctataccaa ttcctatact tatagtaaca ggaagattat ttccataatc aatatgtctt
   118681 attgtatcta aaatagaaaa cttctcagct tccaattttt ttaactcttt tttatgcatt
   118741 accaagaaga atttgtcttt tgaagttctt ctcaatgcac catttgaatt taattctaaa
   118801 gcagaaagta ttttctctac ttcaacatta attaaagctc tcttatcttc tgctgcactt
   118861 tttaatactt catcatatcc atctacttgt attagcatca ttgcattttt ttcatcatca
   118921 taattttgtt ttacttttaa atattcagtc ttgtctatcc agtataatat catcaaatat
   118981 ttaggatttt tttcttgatc attttttata acattataaa ttattgtata ttctttttct
   119041 ttatagttta tttctgtgta catctcttta ttttcattta atacttttct taaattaaga
   119101 tttttaacta tatcctctat atttttatca agtaaatctt tttgaccaat catatcataa
   119161 aactttccat tataccagga tatatttcca tcaaattcta aaatacataa tggtattgga
   119221 agatttatta tggctttttt agttgtttca tctatatcta aagataaatt ttgaatatac
   119281 tctgtccatt catgacgtct aatattagta gttctccaat tgtgaaaaac catatataca
   119341 aaaatacaga aaaataaaca ccctacatac aagttgtaat aaagcaaaat tatactagaa
   119401 ataccaataa caattatata taaatttatt tctggcatat ttaatttaaa ggcttgttta
   119461 ttactcattt ctatcctcct aagtggattt atagcttctt acctttctaa agtcaattat
   119521 actatctacc ataccaacaa aagatattcc cataaatcca aataaacata aaattatccc
   119581 tgaaaaaaac ataattttat ttggtccctg tcttatccat ttctttaaga aataaatgca
   119641 aactgctata ccttgaatta caaacattaa attaaaaact agctgtaaat tagtcattat
   119701 taattctgta tataattttg aaccaataat ttgaataaat aagactaata aataaagtaa
   119761 gaaagttgtg agtatagcat ttcccggtaa ataaaaatca gcaaacttag gaaatcttat
   119821 attcatcttt gtaatccttt ttataaaaaa tacactcaaa taatatgtga caaacgctga
   119881 taacaaccct tgtaaaaata acatcattgg tagcatattt gtaaaataac ttacaatctc
   119941 atctggcttc attttatcaa acactttaag ttcagttgca gaaaaactat ttttttgaat
   120001 atttacaatt tctgatatca tcttagaaac ttcatctaat agattcacat ttaaaaatgt
   120061 ctttaataca aaaaaatata caagcattga aagtacaaat attatggttc caccatatat
   120121 cggttcgaat ttattactgt cctcttgttc aaagcttctc tttagcatct ttcctattac
   120181 tatacctggt aaagaataca ttatacatat atttaatgcg taagaaatat ctgcaaatag
   120241 aatcagtacg caaaatgtaa ccaaaataga tataagagaa tactttctat cagtaatagc
   120301 acctataatt acatatggaa cagctgctaa catactaaat attcctagca ttggaatata
   120361 ggctattact aaagcgatta ttatagctaa aactattata gacattgcct tagatagtct
   120421 aattttatta ttcaatttaa tatcactccc tattatccat atgttttttt aaattagata
   120481 aatccccata ccatctttca acgctatggt cctcatctat accaattttt attttttcct
   120541 tgactttata atccacatct ctaaaactaa ttcctaatct ctttgctaag agatatgtta
   120601 tcattattat atttgctaaa gtatcttgaa ttgcttcatc taatggtttt acccctttaa
   120661 acaataaatt aaacaaatca cttacactca ttaatatttc tgttttcatc cattctatta
   120721 tctttatgtt tctcgttatc tcagaacctt tatctatttt cacgtttaca accctcctta
   120781 atatataata ttatatcata aataataata tatttaagta tataaacaaa aaaacgagct
   120841 ttatagctcg cctcatttag atatataaat acatataata aaaaatgagc acaaggctca
   120901 tttttttagt ctaatgtata tggtaaaagt gctatatttc tcgctctttt tatagcaact
   120961 gttaattctc tttgatgctt agcacaagtt ccagatattc ttcttggtaa tatctttcct
   121021 ctttcagtta tatacttttg taatctttga gtacttttgt aatctatttt agcgtttttg
   121081 tcagcacaaa attgacaaac tctttttttc ttacgtcttt ttttattcat catgactttt
   121141 ttccctcctt tttaaaatgg tatatcgtca tcatctatag cttggaaacc ttgtgggtct
   121201 aaaccttgag gttcaaagct tggctcaaaa gctggagcac tctctctata tgaattttcc
   121261 gatttattct tactatccaa agcttgtact gatctagtac ttacttttgt aaaagttctc
   121321 ttttcacctg attgtgtctg ataattgtct actcttatag atccttgaag tgctactaat
   121381 ctacctttag ttatgtagtt agcacaaaat tcagcagatt tacccattac ttcaacaggt
   121441 ataaaatcag tttctttaga tccatctttt tttacatagt ctctatcaat ggctattgta
   121501 aaggatgcca ctggtgttcc tgtacctggg atgtatctta attcagggtc tctagtcaac
   121561 cttcccacta atacaacttg attcataaaa acaccaccta ttttttataa taaaaccagt
   121621 tattaagcaa caactatcat gtgtcttatt acgttttcat ttatctttaa gtttctgtct
   121681 atctctttag gaacgtctac tgctgatttg aagttaacta atacatagaa accttctgta
   121741 aacttagcta ttggataagc taatttttta gttccccaag tatcaacttt aactatttct
   121801 ccgtcagttg caacaacttc cttaactttg tttagtatag cctctcttac ttcttcatca
   121861 gagtttggct ttaccacata aactaattca taatttctca ctataattca cctccctttg
   121921 gacttaacgg ctctacactc ttagagcaga gaaatgagac taaaatctca tacctacaca
   121981 ttttatcatt tattcttatt tctgtcaatt taaattttgg acaaagttta gtataaggtg
   122041 aattatatac ttttcaaaca aacaagggat ggcaacaacc atcccttgta ttatatataa
   122101 gttattattt ttaattaagc ttctacaccc atagcttctt ttaatacagc tgctatattt
   122161 tttatacctt ctattatttt ttcttctggc atatttgaat agttaagtct gaaagtattt
   122221 tctctaccac cattagggaa gaatcctcct ccagcaacat aagcaacatt cttatctaaa
   122281 cattttggca ttaattcttt agcatttaaa ttacttggaa gctctaccca tgtaaataat
   122341 ccaccttctg gatgagtaaa tactaatcct tctgggaact cttcttccat agtcttaagc
   122401 attacatctc tacgtttaac ataaactgct tttattttgt caacatgtgc atctaggtca
   122461 tacatatcca taaatttgct tacttccatt tgagatatag ttgatgcttg taagtctgca
   122521 ccttgttttg caaagttaaa cttagataaa atttctggag aagcacaagt ccatcctaat
   122581 ctgtatcctg ggcagaatat tttagagaaa gttcctaaga atattactaa tccttttgta
   122641 tccattgatt ttaaagatgg taaagtctct ccttcaaatc ttaaatctcc atatggatta
   122701 tcttctatta ctggtatttc aaatttattt actatttcca tgaatttttt acgtctttca
   122761 agtggccaag ttcttcctgt tggattttgg aagtcaggta ttacgtaaat catttttatt
   122821 ctatcagttg tttctagtat cttttctaat tcttccatta tcattccatc agaatctgtt
   122881 ggaacatcta tgaatttagg ttgataagat ttaaatgcgt ttatagctcc tatgtaagat
   122941 ggactttcac ataaaattac atcaccctca tcaataaata cttttcctgc aaaatctaga
   123001 ccttgttgag aaccacttgt aactaatata tcatctttgt ttacattagt tttgttttta
   123061 tcattcattc tagctgctat tttttctctt aatggttcat atccttctgt tgtagtatat
   123121 tgcatagctg atcttccatt ttcttcaagc actgcaactg atactttttt catttcctca
   123181 actggaaata actctggagc cggcattcca ccagcaaaag atattatttg tggttgttga
   123241 gtaagtttta aaagctcacg tatttctgat ccttgtaatc cttgcattct ttttgcatat
   123301 ttaactgcca taattaaagc acccccatga aaatgttttc ttcaattctt attataccaa
   123361 aattttggat attaatatac ggtatttgac attttttaag tgttaaattt ttatcacttt
   123421 tttattagct tttttactct cttttctaag gtctctctat caagcattat tagccttgaa
   123481 catctagtac attttatctt tatatccatt cccgttctta tgatttcaaa ctctttacac
   123541 ccacatgcat gttgcttttt taattcaaca atatcaccta tttttaaatc cattggcata
   123601 aataattagc ctcctaatct aacttctcta cttcttttga accattttct aatttactta
   123661 tacaataaat tccttttata tctacattat tttcaaccaa aatagttttt atcttttcca
   123721 tatcttcaaa agaaaattta attgatattc cacaacttgc tgttatttct cttggtgttg
   123781 gaagagccat tacttttaga ctattttcac caaataactt ttctgatctt atcgcatgat
   123841 gtgtcgaatt aaatgacact atatacattt gattcattac ttaatccttt ctgactatct
   123901 atttgagtta atctttattg ttagttttat attattaaac atacatacat tatatagaaa
   123961 tggtatttga tgcattcttt aatgtctcaa ctatagtata catatttgta actgtaccta
   124021 cttgtaattt gtcttttaaa ttataataat ctaaacaagt accacaagat aaaacttcta
   124081 cacccatatt ctcaagtatt tttagatttt ctatggtttc ttcattttca gcacttaatt
   124141 ttactcctcc attaactaaa agtacatact taggataagg tttagattct gttaatgtat
   124201 atataaatcc ttttattaac acttttccta attcgtcatt tccaagtccc atcttatctg
   124261 aagatataaa tatacatgta ttgtctaatt cactttcttt attatctaca acattttgtt
   124321 tatctagtat atttttacct tttctaattt ctatagatat aaaattctct ttttcgtcaa
   124381 caatatttgc ttcacaactt aaagatttag caagttttaa tatattctcc ttagctgttt
   124441 cattatcaac tattgtaact acaacacctt cttctaggtt atccaattct ctttttgtat
   124501 ttataactgg tttaggacaa gcaagccctc tcgcatctat ttttatactc attgtctgat
   124561 tcatctcctt aaaaatattc atacaattta tattttatca tagatattat cttgcttgtt
   124621 atagattgtt tctataccct tataggttta tttaccctac attatttcta agtttttgta
   124681 cataaataca cctttttgat aatattctaa ctctttttct tttgatatat ttgaatataa
   124741 ttgacctaag tctatatata aattggccaa tattctattg ttgcctaaat ctgatactat
   124801 ttttatgcat ttaatcagat attcaattgc aagagttact tcattctgat ttttatacat
   124861 attagcatag aatctcaatg ctttatattc attgaattta tttttatttt ttattgatga
   124921 agctaaggct atcttacaat attttctagc taaatcataa tcttctttat ctatatatgc
   124981 ttctattatc ttaaataatc ctgacatcat gtattcatct tcatcatttt tctttatgtc
   125041 atataccttt tgtgaatatt caagtactct atctgtttca cctatttttc tgtaaacatc
   125101 acaaattgtt aaatacacat ttgctaatcc agttttatta tcctcactct caagtatttt
   125161 tagtgctttt ttaaagtaat ctcttgattc ttcatatttt ccaatctcaa gcatattatt
   125221 tgcttttaac accaaaatat cgacatcttc ttttctatca tttctattat ctatttcatt
   125281 tatcttttct atgtacttca atgacatatt tggattatct agttttatgt aacaatatgc
   125341 catcttacta tatagttcct tgtgtatgtt aacatcctca aatttactct ctgacaaaat
   125401 ttcctctgca aaattaaagt ggcttatagc acctttataa aagtcttcct gcatatatat
   125461 tttccctatg tttaaataac acttaagtat attttcacta tcactatttt ttataaagaa
   125521 gtacaatgcc ttttcaaagt tttctatagc atcattataa ttagattttt tcaaattaat
   125581 attagccatt aaaaaattac atctgccata gttctccatt aaatcgtatc tcttacatat
   125641 atctaaaact tcttttattt ggtcctcagc cttgtttaat tcattttctt ttatataaat
   125701 ttcgctctgt agtattaaat tatcagttat cttttttgat tgcatttcct tggtctctaa
   125761 taagtattct acacttacat ctagcttatc gcctagatat tccaacagtt cataactagt
   125821 atgagattta tctctctcta tatggcttat ttgtgctgct gttatcctat ctccagctaa
   125881 ttctttcaat gtcatgtttt tttcttttct taacttttta atcttttctc ctaagctcaa
   125941 aatttccata ctattcccac cttttgaaga cattttttta taatataatt ataacttata
   126001 tttattttaa aaacactact tttattttac aatattttca ctgtacatta aatgatttcc
   126061 cataaaaatg actaaaattt agtttatttt gagttttatt aatttaaata aatcattttt
   126121 taaatttgtt actattttgt attcatatat ttgctcataa cgactataat tatatataag
   126181 aatagttttt aagagaggag aaatttttat gaaaaataag aaaataatgt tagtgttaag
   126241 tatattatct atatctatat tcgcagttgg ttgtactaat gctcaaaatg gaagtgattc
   126301 atctaaaaaa gaaactaaga gcaatacaaa tgttgagcaa ccaaaagaag aaaacaatac
   126361 tgaaaaagag gttcctaata acaaagctaa acctactcca aaagaagaaa ctaaagctca
   126421 atcagctact atttactctt ttgatgtaga taagacagat ttaattgaaa ataaagttga
   126481 tttaaataaa attgatgaga acactttatt tgaagaactt caaaaactta aagttgttcc
   126541 agaatctgca aaattaaatt catttactac aaaagacatt gatggtgtaa aaactggtat
   126601 attagatgtt agctctgact ttacaaagtc aaacttaggt agtgatgcag aaactttaat
   126661 gcttgattca gttgctcgta cttacataaa aaatatgaat gttgaacaaa taaaaattac
   126721 tgttgatggt tctaattacg aaagtggtca tatagttctt gaagaaggag attacttaaa
   126781 gtaatttctt gaaactatta tcaaatagat tagaggttct taggaacccc ttttcttttt
   126841 tgtacaaaaa aggagatgat tcaaattttt attttgaaat atcccctttt tttatttcta
   126901 tattattaaa tctcatgcta tttatttttt gaaatttttt tcaaagcttc cactgcttta
   126961 tctatctcat cttttgtgtt gaaatatcct atactgaacc ttactgcacc ttgttttaaa
   127021 gtacctaaag tggtatgtgc tagtggtgaa caatgtattc ctgatctagt cgctatatta
   127081 taatcactat ctaataagaa agtaacctct ccagaatcca tatctcctat atttagagct
   127141 attactgatg ctcttttttt actgtccttt ggtccatata tctttatatc tggtacttcc
   127201 tctaatttgt ctatcatata ttgacataat tcttcttcat gttgtcttat attgttgatt
   127261 cctctttcaa atataaatag tataccttgg ttaagacctg ctatacctgg agtattatga
   127321 gttcctgatt catatttatc tgggaataac tctggttgaa ctatttcttc tgatttacta
   127381 cctgttccac cttcttttaa tatatttaag ttcaaccctt ctcttacata taatatacct
   127441 gttccttgag gtccaaataa gcatttatga cctggcattg ccaacatatc tatattacat
   127501 tcatttacgt ctatatcata aacacctgct gtttgtgatg catctactaa aaatagtata
   127561 ttatgttttt tagctatttc tccaactttt tttatatcta ttaaagttcc acatacatta
   127621 gacgcatgtg ttgttacaat caatttagta ttattcttta ttgatttttc taaatcttca
   127681 taatctaaaa atccctcata atcgcatttt actacagtat tttcaatacc ccttttttcc
   127741 aatgctttta taggtcttat tactgaatta tgctccatag acgttgttat tacatggtct
   127801 ccttcttgta atacaccttt tatcgctaaa tttaaagaat ctgttgcatt agatgtaaat
   127861 actatattca taggattact tacattgaac aacttagcta tattctctct tgtatcatat
   127921 atctccctag cagctctcat agcaagttta tggccggctc tacctggatt tgcacaataa
   127981 tttttcatac aatctaaaac agcattatac actctttctg gttttggata tgtagttgca
   128041 gcattatcta aataaatcat aacaatcttc ctctctgttt tatatttttg ttctattcaa
   128101 gaagcattga tacaatacta tttaaatcat catcattata gtattctatc tctattttac
   128161 cttttttctt tcctttagaa atattcacct ttgttccaaa tatatttcta agtttatctt
   128221 caacatctaa aataaataca tccttaggtt tagatttttt aggttcttct tgtttatttt
   128281 cagatatttt tttagctata ttttcgactt ctcttacaga aagttcttct tcttctattt
   128341 ttttcgctat ttgaagttgc aaatctttat ctgcaattct caataaagcc ttaccatggc
   128401 ctgctgtaat tctaccactg tctatcattt ctataacatc ttgtccaaga tttaaaagtc
   128461 ttagtgtatt agttatatga ggtctactct tcccaacagc ttctgatatt tcttcctgag
   128521 ttacattgta atgctctatt aaactcttat atgctagagc ctcttctatt gaatttaaat
   128581 cttccctctg taagttttca attaaggcta tctccattat atctttcata tctatatctt
   128641 taattatagc aggtatttga tttttatttg caagttttga tgctctaaat cttctttctc
   128701 cagctattat catatattta ttattttcat ccattttaac cactattggc tgtaaaacac
   128761 cataattttt tatagagtca gacaatactt ttatcttttc ttcatcaaat tgctttctag
   128821 gttgaacttc gtttggatat attttgtcta tatctatgtt gactatttct ttttctgaag
   128881 tttctccttt aatttctggt atcaatgcac taagacctct acctaatcta ttacttcttt
   128941 tagacttatt ctccatacta ccattcctcc tcttctaaat ctataaattc ttctgctagc
   129001 tccaaataag ctacagaccc tctacatctt ttatcataat aaattacagg ttttccatga
   129061 cttggagctt ctgcaagtct tacatttctt ggaattaaag ttgtatatac actaccttta
   129121 aagtatttct taacttcttc aactacttgt attgataaat tagctcttcc atcaaacata
   129181 cttaaaacaa caccttgaat ttctatatca gcatttaatc ttgattttac taattttata
   129241 gtctccatta attgactaac accttctaaa gcataatatt cacattgtat tggaattaaa
   129301 acactatcta cagcagttaa acaatttatt gtaagcatcc ccagtgaggg tggacaatct
   129361 aaaaatatat aatcatattc atctattacc gcttttatgg aattttttaa aatatactct
   129421 ctattagttt tagatgtaag ctctatctct gcacctgata gttcagtagc tgatggaact
   129481 acatctatat tctcaaattc agtacttatt attgcttctt taatatgtaa cccatctaac
   129541 ataatttcat agattgtatt ttctacttcg tttttattaa taccatatcc actagttgta
   129601 tttccttgtg ggtctaaatc taatactaat attttctttc ccaaagttcc taagctagca
   129661 cttaaattta catttgttgt agttttcccg actccaccct tttgattgaa tacagctata
   129721 actttgccca tgatgttccc ccctttaaga attaaattaa ttttaaatgt tgaataggtg
   129781 ttttttaagt ataaataatg tctataaatc agtttatatt acaaggctta tattacaaaa
   129841 aaagattact ggtaagcagt aatctctatt ttttagggat ttttacaaca acttccatat
   129901 aatctccctt atctatttca ttatacttag catcaattcc tgtatttgat atagcatcaa
   129961 aggcctgctt tatagtattt atgtaaattc ttatactcat agcacccttt atattctgtt
   130021 ttttatcagg ctcttcttga actttagttt cttctaatac atcttgtatc aatttttctg
   130081 tttttttaac agtcaattca ttttttatga ctttgtctaa cacactttgc attaaatctt
   130141 cacttggtag tttaagaaat gctctagcat gtctttctgt taaattattc tctattagct
   130201 tcatttttat atcgtttgga agctttaata ttctaagctt atttgctaca gtagattgat
   130261 ttttgcccaa tttttctgct aattgctgtt gagtaaaagc atgttctttt attaagtttt
   130321 cataaccaat tgcttcttca atgaaattta agtcttctcg ttgcaaattt tctaataacg
   130381 ctagaacagc agaagattca tcgttcatat tatttataat tgctggtatg gttttaagtt
   130441 ctgctaattt agctgctctt aatcttcttt ctcctgcaat tagttcatat ttgccatctt
   130501 ttgctctaac tgttataggt tgaattatac catatacctt tatagaattg ctcaattcct
   130561 ccaatgaaac ttgtgaaaat atttttcttg gttgatatgg atttggaact acatcttcta
   130621 taggtatctc cataactctt ttatcttcca taacatacct ctcttatttt agatataaat
   130681 tatttttgtt ctctatatgt acatacaaat ttatttctgc atctacttta ataattcctt
   130741 tatttttgtt tttttacagt aagcttaatt atttcctgag aaataattaa gcttaccaat
   130801 aataaatttt tcattactta ataggatttt tggctggttt accagctttt ctagggtact
   130861 taactggtgt ttccatcact tttttaaaaa ctaatatatt atgatttaaa tctacctctg
   130921 gtaactctac atctattttt tcaatatact ccaatcctaa aacatcaata gccttttgtg
   130981 attcttctag ctctaaatta gcattcggac cttttaagca aataaaatac cctccaactt
   131041 ttacaaatgg tacacaaaat tccataagaa tcggtaatcc agcaacagct cttgccgtag
   131101 caacatcata tttttcccta tagtcttcat ttttaccaaa atcttcagct cttccatgta
   131161 taaatgtaat attatctaac tctagtactc tactaacttc ctctaaaaag tttattcttt
   131221 tatttaacga atctaacaaa gtaagttcta agctatctaa acatattttc aatggtattc
   131281 caggaaaacc agcacctgta ccaacatcta ttatagacat cccatttttt atatatccat
   131341 tctttacagc tgaaatagag tctaaaaaat gttttatata cacttctttt tcatcttcta
   131401 ttccagtaag attcatcttt ttattccagt caactaatat ctctctatag attttaaatt
   131461 tttctaacat actgtcattc gtatctatat taaaaccttc aatcccgttt ttcagaagtt
   131521 ctatattatt cacctttgcc acctctagtt cttctgattt gttctaggta tataagtaaa
   131581 actgatatat cagctggaga aacaccagat atacgagatg cttgccctat tgaaataggt
   131641 tttatatcat ctagtttctg tctagcctct aatctaagac cttctataga tgaataattt
   131701 attttctcat ccagcttttt attctcaagt tttttaaatt ggtctatttg tttcaattgt
   131761 ttctctatat aaccttcata tttagttatt attacacact gttctttaac ttctcttgaa
   131821 acatcatctc cagcgccttt ccctaattct tcaagcaatt cgtaagtaac ctctggtctc
   131881 tttaaaaatt catatagaga tattccaacc tttattggtg ttgctccttt ttcttctaac
   131941 aaactattta cttcttttgg tgtaactctt tcatttttta gtctttcaaa ttctttctct
   132001 acagcagcct ttttatttag aaacctttca tatctatctt ttttaactaa tcctatatca
   132061 taaccttttt gagttaatct catatctgca ttatcttgtc ttaaatatag tcgatattct
   132121 gctcttgatg tcatcattct gtaaggctcg ttagttcctt tagtaacaag gtcatctaat
   132181 aagacaccta tataagcttc tgaacggtct aatacaaatg gctcttttcc ttctatcttt
   132241 ctaactgcat ttataccagc cataagccct tgagctgctg cttcctcgta tccagaagtt
   132301 ccattaaatt gccctgcact aaataagttc tcaacaccct ttatttccaa acttattttt
   132361 agttgagttg ggtcaacaca atcatattca atagcatatg caggtctcat tatcttacaa
   132421 ttttcaagtc cttttatagt tttgtacata tctaattgaa cttcaaaagg taaactagtt
   132481 gaaattcctt gtatatacat ttctttagta tttaaccctt ctggttctat aaataattga
   132541 tgtgatgttt tatcactaaa tcttactact ttatcttcta tagaaggaca gtatcttgga
   132601 ccagtacttt ctattactcc actatacata gcagaccttt ttaaattatc cagtataact
   132661 ttttgagttt cttctgtagt tcttgttaaa taacaaggtt cttgtttttt ttctatattt
   132721 tcattcataa atgagaatgg agttactttt tcatcaccct cttgtaaaga cattacagag
   132781 aagtctatac tatctctatg aactcttgct ggagttcccg tcttaaatct tctcattcta
   132841 aggccaagct caactaagct atctgtaaga tattttgcat accccaatgc attaggacct
   132901 tcataaaatg caacttcacc catatatatc tttgagttca gataaactcc agtggccaat
   132961 attacagctt tagatttaaa tgaacatcct agtttagttc caactcctat tacaacattt
   133021 ccttcatgaa gtatttctac aacttcatcc atagctatat caagatttgg ctcatcttct
   133081 aatgtctttt tcatttcttc atgatattta aatttatctg cttgtgctct taaagagtgt
   133141 accgctggac ctttggcagt atttaacatt ctactttgta tatatgtctt gtctatattt
   133201 aatcccatct gaccgcctaa ggcatctatt tctttaacta attgaccttt accagtccct
   133261 ccaattgatg gattacaagg cattaatgct atggaatcca aagacattgt tattatcaaa
   133321 gttttatatc ccattcttgc agtagccaaa gcagcttcac atccagcatg tcctgctccg
   133381 actactataa catcatattt tcctgcttca aactttatca tttataattc ctttcttttc
   133441 aaaattaatg tttcatgaga aacacttcaa attttttaaa aatctctata ataaaaacaa
   133501 gtttactttt gtacattact taccaataca gaaattatgg aatatattat ctagtaaatc
   133561 ctctgttact gtatcaccat taatatatcc aagatagtcc catatatttt ttaaatcgac
   133621 ttctacaaag tcaaatggca tactttgttc caaagcaatt aaagcatctg ttgcagattt
   133681 atatgcttta ctaagtgcat ctttatgtct tgaatttgtt actactaaac tagaattatt
   133741 tttgatacta cctttatata ccatagactc tattttatct tgcaattctt ctattccttc
   133801 ttgttgtaaa gctgatattt ttattatact attattttct acatatttaa gtattttttc
   133861 ttcttcaatc tcttgtttca aatcattctt atttaacagc actattgttt gtttatcctt
   133921 aagtttttct aatatctcta tatcttcttc tgacaacttt ctagatgcat ctaaaaccat
   133981 tactatcaaa tctgcactag taaatgattc tttagacttt tcaacaccta ttttttcaac
   134041 aatatcatca gtatctctta tacctgctgt gtcaacaatt tttaaaggta taccttttat
   134101 gtttacaaac tcttctataa catctctagt agttcctggt atatcagtaa ctattgctct
   134161 attctctcct aaaatagaat taagtagtga agatttacct acatttggtt tcccaacaat
   134221 taccgtcttt aagccttctc taagtatttt tccactttca gctgtatcat ataatttttt
   134281 aatgtctttt ttaagttcat cagttttttc tttaagagtt tgatatgtta tatgctcaat
   134341 atcttcctca ggataatcta tagcaacttc tacatgagct aatatctcag tgactttatc
   134401 tctcaattct cttatcttct ttgataaaga accttctaat tgattttgag caacttcatg
   134461 agctatatca gttttggctt ttataacatc aattacagcc tctgcttgag ataaatctat
   134521 tcttccattt aagaatgctc ttttagtaaa ctcaccagcc tctgctaatc taacatcttt
   134581 tgatagtatt aattctaata tcttctttac cgaaataaat ccaccatggc aattaatttc
   134641 tataacatct tctcctgtat aggaatttgg tcctttcata tatgccaata aaacttcatc
   134701 aattatattt tcattatcca ctatatttcc atatattaat gttctcttat tgtattcttc
   134761 aatactcttt ccagacatag atttaaagat ttcttctgca accttcaaag ctttttctcc
   134821 acttattcta agtataccta taccaccttc tccaggtgct gtagctattg ctgcaattgt
   134881 atcatctata aacaaattta tcacctctta attcataatt ttttacatat agatttacat
   134941 ttaaccaatc attaatgatt taataatatt aaaaaataaa accccctaat gtttaggagg
   135001 ttgactttat cttttacact caattactaa tcttctatat ggatcggttc cttcactata
   135061 tgtaattaca tatttgtcat tttgaagagc tgaatgtatt attcttctct catatggatt
   135121 catataatct aattttttag tttttcttgt tttcgctact tctctagcaa ctttattagc
   135181 atatcttatt aaagattctt ctcgttttga tctataattt tctatatcta caagtactct
   135241 tgtatgagaa tctttattta ttttattaag agctaatcca gtcaaaaatt gaatagaatc
   135301 taaagtttcc cctcttctac caattaaact tgcagcttct ttgccttcaa tatcaaccat
   135361 gattaaatta tctttttgag atacattgac tttggcatca acatttgcat ttttcaacat
   135421 tacctctata aaatttttag ctacatctac ttccctctcg ataacaaaaa tttcataagt
   135481 accatcttta gcacctataa aacctaaaaa ccctttactt ggattttcaa gtatttctac
   135541 ttctatatcc tctgctttta aattcaactc tgctatagct ttacttatag cttcctcttt
   135601 actcttactt tttattaatt ttaggctttt tctcattaac tttttcctcc ttagagttag
   135661 cagccagttt agcttttaaa ggattcatta ttaagtaata ttgagctatt gagaataagt
   135721 tacttactgt ccagtacaat gtaagtcctg ctgggaatat aaatccccaa tagaaagaca
   135781 tacctgccat tacatatgtc attactttca tagagccttg taactgatct tttggtgtca
   135841 ttactttttg catgacatat gcacttgctc ctgaaaatac tgctaataca taatctggtg
   135901 atgttaagct ttttatccat aaaaacccat tgtcagctgc taaaaatgca gctttgtttg
   135961 caaaaacgcc atgagcaact ggttctctca aaacgctaaa taatcctatt aatataggaa
   136021 actgtattaa taaaggtaaa caaccagata gtggattaat tttagcttct ccatataact
   136081 taacaatttc ttcattttgt ttttctggct tatttttata tttttcttgt atctctttta
   136141 tacgaggttg tatatcttgc attgcctttg ttgacttagt ctgcttaatt gttaatggta
   136201 ataaaataat ctttacaagt atcgtaaaaa gtattataga aataccataa tgattaacaa
   136261 attcaaatat taccttaaga atcaatccta agaaatttcc tattatattc aattttttta
   136321 tacctcctaa tagttactct cttttatttt agagggtcgt aacctcctgg atgaaaagga
   136381 tgacatttta aaattcttct tatcgttaaa tacatacctt ttacaaatcc atatttctta
   136441 aacgcctcta ttgaatattg tgagcaagtt ggataaaatc tacaggtagg tccctttaag
   136501 ggagatatat acttttgata aaatctcact aaataaatac ataaattcga taaatactta
   136561 cttatttcct ttaatatata aattatttta ttcaaagtca ttaacctcca tatttatagc
   136621 atacaattaa atagaaatat ccgttctttt aactaaattt tttatagact tgtctatgtc
   136681 tttaaaagta gcatccttac tagataccct tgctataaat actatatcat atccaggctt
   136741 aattttttca tcaatattta atctgtaggc ttcttttatt aatcttctta ctctattcct
   136801 agtaatagct tttcctactt tttttgaaac agaaatacct actctactat aatctgattt
   136861 atttttaagt atatatatta ctaaatattt gtttgcaaaa gatttgccgt gtttatatac
   136921 ttttctaaaa tcagagtctt ttttcaaccc tttagtccta ttaaagtcca tagttaacct
   136981 ccataaacac agctatgaat tgtaattatt tacacaaaaa ggccaccttt gcagcggccc
   137041 ttttgtaatt aatgagttaa tctatttctt cctttagctc ttcttctctt taacacgttt
   137101 cttccgttag acgtcttcat tctttttctg aaaccatgtt ctttacttct ttgtctcttt
   137161 tttggttgat aagttctttt actcattatt ttgcaccgcc tttcagattt tattttccgt
   137221 ttataaaaat aataacttta ccctcaaagt aaacataaca catataatta taaatacttt
   137281 tactactgtt gtcaacgagt ttttgggacg cttatatcac aaaatctacc atatatatat
   137341 tatgtatttt ttttattgaa aatactagta aaaatctatt taattttatt ctaaattatt
   137401 tttttcaatt atatacacaa ataaagtaat tttaacatgt ttatattttt atcaacaatt
   137461 agttaatatt gtggataaat tagttacaaa tcattgaagt ttgacatata ttttgatatt
   137521 ataaatatac ttgttgataa tgtgcataaa tgttatcaac ttattagaaa ttattcacag
   137581 cttgtggata cttttgtgta taacttttaa gattactgac aatactctag ttataatcac
   137641 catttattgt atgtttatgt tatttataac tttatctaca tattgtttat atcttttcat
   137701 atttttttaa taatttatac tattattaat ttatcaacac cattatccat aaatttagtt
   137761 attctgtaaa atttatatat atttttgctt ttctgttaat aactttgtgg aaaatattaa
   137821 ttattctgtt cggaggttta tattatggat atagtttctt tatgggacaa aaccctacaa
   137881 ttaataaaag gtgacttaac ttcagtaagt tttaatacct tttttaaaaa catcgtacca
   137941 ttaaaaatac atcttaatga tttaatctta ctggctccta gtgattttaa taaagatatc
   138001 ttagagaata gatatttaca tttaattgaa gatgctatta gtcaactgtc attaaaaaaa
   138061 tataatatta aatttgtatt gagcgaaaaa gaggttgctg atttaaattc tgatagcaca
   138121 gatttaaatt atagagttct ttaccccaat ctaaatccaa aatacacatt tgatacattc
   138181 gttattggta atagcaatag atttgcacat gctgcatgcg ttgcagttgc agaatctcca
   138241 gctaaagctt ataacccact ttttttgtat ggaggagttg gattaggtaa gactcaccta
   138301 atgcatgcta taggtcatca tattgttagt caaaaaaaag actcaaaagt agtttacgtt
   138361 tcttcagaaa aatttactaa tgaacttata aactctataa aagacgataa aaacgaagaa
   138421 tttaggaata aatatagaaa cgtagatgta ttactaatcg acgatattca atttatagca
   138481 ggaaaagaaa gaactcaaga agagtttttc catacattca atactcttca tgaagcaaac
   138541 aaacaaataa ttatatctag tgatagaccg ccaaaagaca tacctacact agaagatagg
   138601 ctaagatcga gatttgaaat gggacttata actgatattc aagcacctga ctttgagaca
   138661 agaattgcta tacttagaaa aaaggctcaa ctagaacgta tagatgtgcc aaatgaggtt
   138721 atgtcatata tagcaaaaaa tattaagtca aacataaggg aactagaagg tgcattaact
   138781 agagtggttg cttattcttc tcttagcaat agggtaatat cttttgatct tgctacagaa
   138841 gctttaaaag atattataac aacttctaaa aatgaagaaa taaatgttct cagaataaaa
   138901 gaaaaagtat cttctgtatt caatttaaag atggaagatt ttaattctaa aaaaagaaca
   138961 cgttcaatag cttatccaag acagatagct atgtatttaa cgcgcgagct tactgattta
   139021 tcccttccta aaataggtga agagtttggg ggtagagacc atacaacagt aattcatgct
   139081 catgacaaag tatctaagga tatagaagaa agtgaagaaa ttaagactaa aatagacaaa
   139141 attatatcag atttgaaggg ataatttata cacaattgta tgtttatatc tcttgaataa
   139201 cctgttaata ctttttttga acaaaaatta ttaacaaatt atcaagtcta aaataacaaa
   139261 gatattaaca tcttatacac atgttaatat ctttgtattt ataatgttat acatacttat
   139321 taacattatc aacaacacct actactatta ctactatgat tttaacttat ttttatatat
   139381 aaaaagccag aggaggttat ccacattgaa aataatttgt aatcaaaaaa tcctagcaaa
   139441 tagaattgga attgctcaaa aagctattaa tggaaaaaca acaatagaat tattaaaagg
   139501 tatacttata tctacagaag aaggtcaatt aaaacttact ggatatgatg ctgaaatagg
   139561 aatagaaact tatgtacaag cagaaatcat agaaaaaggt gatgttgttg tagatgcaag
   139621 gctatttgga gatataatta gaaaattacc agattccttt gttgagatag aaactgattc
   139681 agaaaataat atttacataa attgtgtaaa ttcaagattt aaaattaaag gttatgcagc
   139741 aaaagaattt cctaaattac cagaattaaa tgaagaagat ttatatagca tacctcaaga
   139801 aatcctaaaa aatatgatta aacaaactgt atttgctatc tcacaggacc aaacaaaacc
   139861 tgttttaatg ggagaacttt tagaaattgt agatagaaac ttaaatttag tagcaattga
   139921 tggatataga ttagctgtaa aaagttgttc ggttgatagt ttaactgaaa atataaaagt
   139981 cataattcct ggaaagacac ttatagatgt aaatagtttg ctttctggag aggataatgt
   140041 taaagttgga tttaacgaaa aaaatgctat ttttataatt aatgatacga aaattattac
   140101 aagattgctt gaaggagatt ttattgatta taaaaaatta ttgccaagag aacataacag
   140161 cagagttaaa ttaaatacta aggaactttt aaatagtata gagagagcgt ctttattgtc
   140221 tcaatcagaa aaaaataatc ttataaagtt atctataaga gataaagtaa tggcaattac
   140281 ttctaataca gaaaaaggaa atgtgtatga agaagttgaa atagatttag atggagatta
   140341 cctagatata gctttcaatt ctagatattt tatcgaaggt ttgaaaaata tagataatga
   140401 ggaaatattt atagaattta ctacaaatgt aaatccttgt ataattaaac caacagatga
   140461 tgttaattat atttacttac tgcttccagt aagaatatca tcaaatatat agcagacatg
   140521 aaggagttgt cttttgtaga aaatttttct aatcttagac aactcctttt ataagcatat
   140581 ttatggtata atatactttt agtgtatcaa taggaatttg tttaaaatag tgacaaggag
   140641 gaactattat gactgaaata actatagaat cagaatatat aaagttggat caatttctta
   140701 aattagcaga gattgcatca acaggaggtc atgcaaaatt tttaattcaa gaaggtttag
   140761 tgacagtaaa tgatgaaata gaattaagaa gaggaaaaaa gataaaatca ggagatatag
   140821 ttgaaataga aggaactaaa ataaaagtat tgtaaaaaaa ggagaacttt ttgtgaaact
   140881 taaaagtttg caacttgtta attttagaaa ttataaaaag ttgcatctgg aatttaatgg
   140941 gaaagtaaat ctacttgttg gtaaaaatgg tcaaggaaag acaaatatag tagaatctat
   141001 ttatatgctt tcttttggaa aatcatttag gactaacaaa gataaagaaa tggttagatt
   141061 taatagtgaa aacttatata ttggaggaag tttttcaaaa tataataaat atagtctaat
   141121 agagctaatt attggaaaag ataaaaaagg gataagaata aataaagttc ctttacaaaa
   141181 gatacaagaa ctacttggca acttaaatgt tgttatattt tctcctgagg atttaaggtt
   141241 ggttaaagag ggtcctaaag aaagaagggc atttatagac aaagagatta gtcagattat
   141301 acctaaatat tataaatatc ttaccaatta taataaaaca ctttctcaaa ggagtagggt
   141361 gcttaaaaat atacatgttg atgaagcttt attagatgta tatgatgata cgttagcaaa
   141421 gtatggaagt tatatttata ttttgcgtag agactttata aaaaagatag ctaatatatc
   141481 tgaaaatatg catatgaatt tgactaatgg agttgaaaga ttatcaattc gatataaaaa
   141541 tcaaataaat ataactgatg aagatactat agatacagta tataataaat ttttagccaa
   141601 gttgtcatcg aatagaccta atgatataga atctaagact accagatatg gtatacacaa
   141661 agatgactta aatatattca taaatgattt agatgcaaga ctttttggtt cacaaggtca
   141721 acaaagaact gcttcaatat cattaaagtt atcagagata gaattaataa aaaatgaagt
   141781 tgaagaatat ccagtattaa ttttagatga tgtttttagt gagttagatg aagcaagaca
   141841 aaaactttta gtaaataatt taagcaatgt tcaaatgttt ataacaagtg ctgaagtttc
   141901 acataaaaaa atatttgatg aaaaaaatgt tacaatattt aatattgaaa atggcgatgt
   141961 tattagcata gagaatggag gaaattaaat gaaacaagaa tacggtgcaa gtcagataca
   142021 agtattagag ggattagaag ccgttagaaa aagaccaggt atgtatattg gtagtacaag
   142081 ccctagaggt ttacatcact tagtttatga agttgtagat aatagtatag atgaggcttt
   142141 acaaggatat tgttcagaca tatatgtatc tattaatgaa gatggcagtg ttttagtaaa
   142201 agataacgga agaggtatac ctgttgaaat acatcctaaa actggtaaat caactttaga
   142261 aacagtatta actaatcttc atgcaggagg aaagtttgga ggcggaggat ataaagtatc
   142321 tggaggtctt catggagttg gtgtttctgt agttaatgca ttgtcaaaat ggatggtagc
   142381 agaggtttat ttaaacggaa agatatataa gcagacatat gagaaaggat tgccaacatc
   142441 taagcttgaa gtagttggag aatctcaaga taaaggaaca atgattcaat ttatgccaga
   142501 tgagacaata tttgatgaaa tagagtttaa atatgaaaca ttggagtata ggcttagaga
   142561 actttctttc ttgaataaag gaataaaaat agtatttgaa gataaaagag aaggacaaga
   142621 aaaaagaaaa gaatttcact atacaggtgg tttggtagaa tatattaagt atttaaataa
   142681 atctagaact ggtatacatg atgacatagt ttatatagat aaaaaggttg atgattgttt
   142741 tgttgaacta gctatgcaat atacagatgg ttatacagag aacatatatt cttttgcaaa
   142801 caatataaat acacatgaag gtggttctca tttaagtgga tttaaagcag ctcttactaa
   142861 aactgtaaat gattatgcta agagaaataa atttttaaag gaaaatgatg ttaacctact
   142921 tggtgaagac ataagagaag gtcttacagc agtagtatca gttaaattac cagaacctca
   142981 atttgaaggt caaactaaaa caaagctagg taatagcttt atgagaggta tagttgatag
   143041 tgtaacagtt gatgaactgg ggtctttcct agaagaaaac ccatcaacag caagaatcat
   143101 agttgataaa gctttaagag cacaaagagc tagagaagct gcaaaaaaag caagagaatt
   143161 aacaaggaga aaaagtgtat tagaaagtac atctttacct ggaaaacttg cagattgtgc
   143221 agaaaaagat ccatctaaaa gtgaaatatt cttagtcgaa ggggagtcag cgggaggttc
   143281 agctaaacaa ggtagagata gaaatagtca agctatactt ccattaagag ggaaaatact
   143341 taatgttgag aaatcaagac tagataggat actatcttca gatgaaataa aaaatatgat
   143401 aacagcttat ggttgtggta ttggagaaga ttttgatata gataaggcta ggtatcataa
   143461 aattataatt atgaccgatg ctgatgtaga cggagcccat ataagaactt tattattaac
   143521 attcttcttt agatatatga gacctcttat agatgagggg tatgtttatg cagcacagcc
   143581 acctttatat aaagtgacaa agcaaaagaa ggaacattat gtttactcag ataaagagtt
   143641 aaatatctta ctagatgaaa ttggaagaaa tggtgttgaa cttcaaaggt acaaaggtct
   143701 tggagagatg aatgcagagc aattatggga aacaactatg aatcctgaga caagaacttt
   143761 attacaagtt actgtagaag atgctgcaat tgcagatgaa gtattttcaa tgcttatggg
   143821 tgataaggtt gctccaagaa aagaatttat agaagaaaat gcaagatttg ttagaaactt
   143881 agatatatag agagagggga ttagtataca tggaagaaaa taacaaaata ctccctattg
   143941 aaatagcgga agaaatgaaa aaatcgtata ttgattattc aatgagtgtt atagctggac
   144001 gtgctcttcc tgatgttaga gatggtttaa agccagttca tagaagaata ttatattcaa
   144061 tgagtgagtt aaatttaact ccagataaac catacaggaa gtcagctcgt attgttgggg
   144121 acgttttagg taagtaccat cctcatggag atgttgctgt ttattatgct atggtaagaa
   144181 tggcacaaga tttttcaact agagcacttt tagtagatgg tcatggtaac tttggttctg
   144241 ttgatgggga ttcaccagct gctatgcgtt atacagaagc taaaatgagt aaattatcat
   144301 tagaactact aagagatatt gaaaaggaaa ctgtagactt taaaccaaac tttgatgagt
   144361 cgttaaaaga gccttcagta ttgccagcta gatatcctaa tttattagta aatggctcaa
   144421 atggtatagc tgttggtatg gcaacttcaa tacctccaca taatttagca gaagtaattg
   144481 atgcaactgt atatttgata gataatccag agtgtagtgt agatgattta ataaaatttg
   144541 ttcaaggacc agatttccct acagctgcaa ttataatggg aaaagaaagt atagcagaag
   144601 catacagaac tggaagagga aaagttaaag ttaggtctag agcttttata gaagagctac
   144661 caaaaggaaa acagcaaata atagttacag aaatacctta tcaagtaaat aaggctaaac
   144721 tcgttgaaag aatagcagag ttagttaaag aaaagagaat agaaggtata tcagacctaa
   144781 gagacgaaag taatagaaat ggtatgagaa ttgttataga attaaagagg gatgctaatg
   144841 ctaatatagt attaaataat ttgtataaac attctcaaat ggaagatact tttagtataa
   144901 taatgcttgc acttgtagat ggtcagccaa gagttttaaa tcttaaacaa atattatatc
   144961 attatattaa acatcaagaa gatgttgtta caagaagaac taaatttgaa ctaaataaag
   145021 ctgaagcaag agcacatatt ttagaaggat taaagattgc tttagataat atagatgctg
   145081 ttataagctt gataagagct tcaaagactg ggcaagaagc taagctaggt ttaatagaaa
   145141 aattcaaatt aactgaaatc caagcacaag ctatattaga tatgagactt caaagactta
   145201 caggtttaga aagagataag atagaagctg aatatgaaga tttaatcaag aagataaata
   145261 gattaaaaga gattttagct gatgaaagat tacttttaaa tgtaataaag gatgaaatta
   145321 caataataaa agaaaattac tctgatgaga gaagaacaga aataagacat gctgaaggcg
   145381 aaatagatat gagagatctt ataagtgatg aagaaatagc aataactctt actcactttg
   145441 gatatataaa aaggcttcca tctgatactt ataagagtca aaaaaggggt ggaagaggta
   145501 tttcagcact tacaactaga gaagaagatt ttgtaaggca cttggtaact acaactactc
   145561 atagtagact attattcttt acaaataaag gtagagtatt taaattaaat gcatatgaaa
   145621 taccagaagg taagagacag gctaaaggta ctgctatagt gaatttactt caattgtcag
   145681 cagatgagaa aattgctact ctaataccta ttgatggtaa tgatgaaaat gaatatttat
   145741 tacttgcaac gaaaaaaggt attgttaaaa agactaagag agaagagttc aaaaatataa
   145801 ataaatctgg tcttattgct ataggtttaa gagatgatga tgagcttatt ggagtagaac
   145861 ttacagatgg aaaacaagaa gtacttttag taactaaaga aggtatgtct ataagatttg
   145921 atgaaaatga tataagatat atgggtagaa cagcaatggg tgtaaaaggt ataactttaa
   145981 gtaaagaaga ttttgttgtg tctatgaacc tttgcagtaa aggtacagat gtgttagttg
   146041 taagtaagaa tggttttgga aagagaacaa atatagaaga gtatagaagt caaataagag
   146101 ctggtaaagg aattaaaact tataatatat ctgaaaaaac tggtacaatt gtaggtgcag
   146161 atatggtcaa cgaagatgat gagataatga ttataaattc tgatggagtt cttattagaa
   146221 taagagtcaa tgaaatatca ctgtttggaa gagttacaag tggtgttaaa ttaatgaaga
   146281 cgaatgatga agtcaatgta gtttcgattg ccaaaataaa tattgaagaa gaataggata
   146341 aatatcctat tctttttgta taatgtagtt agataaaaat ttaaaattga aaggagtaat
   146401 tgttatgtgc aataaaagaa gttgtaaaaa aggtggattt ttattattag gagctatttt
   146461 agggtttata tttggtatgt tttttgcacc taaaaaaggt tctgaactaa gaaaagaaac
   146521 aaaagagaag tttaatgatg ttaaagaaaa tccaaaagaa gttctacatg aaacatttaa
   146581 tgatgttaaa gagagaataa taaatttagt ggatgatgat aataatgaag aagatataaa
   146641 gatttcagaa gaagatatag taataagtaa aagctttgat gatgagggag atgttaacta
   146701 atgaatgcat gggggtggca aattggagca gtgttagtag gaagctctgc tcttatagta
   146761 gcaatttatt tagctaaaac tctaaacagc ataaataagg ttgttgaaaa ggcatataag
   146821 attgtagatt ataatgaaag acatatacaa gatattgttg aaaatgcatc atcaatatca
   146881 aagggaatag atgatatagt ttatgtaatt aataaaatat tgagtatagg aaatatattt
   146941 aaaattatta aaaggaaata ggaggttttt acatgtctat gaatattgat tcaaatttag
   147001 attcacaaaa taaattttgg aatgtttgtc ttgatggaga acttgatgtt tctacagcag
   147061 ataaactaaa ggaacattta catgctttaa tagaaaaaaa tatgttagat gtaaagatta
   147121 atcttaaaga tttagattat atagactcaa caggcttagg agctatgata ggtgtattaa
   147181 aaaaattaaa aataaatgaa aaagagatat acatagtaaa tcctaagagt aacgtaagaa
   147241 agatttttac tataacaggt ctagataaaa tatttaaagt ggagggataa actttggctt
   147301 gtgagactat aaagatggaa attactacaa atccagatta tgttagtata ataagattaa
   147361 cagcatctgg aattgccaat aagatgggtt ttccaataga tgatatagaa gatataaagg
   147421 tagcagtatc tgaagcatgt acaaatgcaa taaaacacag taaagatgat gtgttttata
   147481 tagtatttaa tattttagat aatgcaatta atatagaaat tcaagataat ggaaaaggat
   147541 atgatgttag ctcaataagt acaccagatt tagagaatcc aaaagagagt ggtcttggat
   147601 tgtttataat taaaacttta atggatgatg tagatattga atcagaacat aatcaaggga
   147661 caaaaataaa aatgactaaa tatttaggag ttgatattta atgaaaaatg tagctaatgc
   147721 tacacattac ctaaatatgg atacaaaaga gctatttaat ttatataata aaaataaaaa
   147781 tgtagacatt agaaatattc ttattgaaag acatctgtat ttagcaagat tgttagctaa
   147841 gaagtatata aacaaaggtg ttgattttga agatatatat caagttgctt cattggcatt
   147901 aatttatgct attgatagat atgatgttga gaaaggattt gagttctcca gctttgcaac
   147961 accaactata gtaggagaaa taaaaaagta ttttagagat aaagtatgga cacttagagt
   148021 cccaagaaga atacaggaat taagcaaaaa gataagtgat gcgaagatta aattagaaca
   148081 agaaaataag aagcatccaa aggtaaaaga tatagctgat tatataggcg ttagtgaaga
   148141 agatgtttta gaggctatgg aggcttctta tggatatcaa ccaatgtctt tggattcatc
   148201 aagtaatgat gattcagagg ataaagatat aactcttatt gataagattg gaaaagaaga
   148261 aggtaacttt ggaagtatag agtatgaaga ttttattaat aagtttattg aaactttaaa
   148321 tgaattagaa gttaaaattt ttaaagatag atttttcttt gataaaacac aatctagtat
   148381 agctaaagaa ctagggatat cacagatgac tgtttctaga ctagagaaaa aggtagtaga
   148441 gaagctgaaa aaagaatatg aaaaaaattt ataaaaaaat ataaaaaaag tattgaccta
   148501 ctgttttaaa gatggtatag tattacttgt ccttgaaaaa aggaacaaga aataaacacg
   148561 aacattgaaa attaaacagt aggttaattt atat
//
LOCUS       DAMJXI010000002       147197 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.002, whole genome shotgun sequence.
ACCESSION   DAMJXI010000002 DAMJXI010000000
VERSION     DAMJXI010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 147197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 147197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..147197
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.002"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            290..757
                     /locus_tag="PC465_000149"
     CDS             290..757
                     /locus_tag="PC465_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HDF2647486.1"
                     /translation="MKFLNVLVVVEDIEKSKKFYYDVLGLKVICDFGENVVLEGNISL
                     QEKKLWLEFINKSDSEVKFNGNDAELYFEEDNFDTFVERLSTMKDIDYVHLAIEHRWG
                     QRAIRFYDLDGHIIEVGETMSSVCRHFLDSGLSIDEVAKRMDVTVEYIESVLE"
     gene            1888..2550
                     /locus_tag="PC465_000150"
     CDS             1888..2550
                     /locus_tag="PC465_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2647487.1"
                     /translation="MSILEIKNLNKIYGKSETEVKALSQINLKINSGEFVVIVGKSGS
                     GKSTLLHIMAGLETPTNGDVIIDNINISSLDEKKRSALRKEKLGLIFQSYNLIPVLTV
                     EENIKLPTINIKNKDEAYINELMELLGIKDRRMYLPNQLSGGQQQRVAIARALVNKPS
                     IVFADEPTGNLDTKTESDVLSLLKESQKKYNQTIIMITHNIDITKYADRVIEIEDGFI
                     RE"
     gene            2559..5066
                     /locus_tag="PC465_000151"
     CDS             2559..5066
                     /locus_tag="PC465_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2647488.1"
                     /translation="MKLNYIVKKYIMGNKKNTLLIIVSIVISTALFLIMNIISEDATN
                     LMINQAKNEFTLKHAQYINPKDEEIKYIENNTSIDKVGKSMLLGISDIGKGQTLQILS
                     QDKVAEELNDIYTLEKGKLPVAENEIAIDSWYIKQKKIKNPIGKRITLDYRRQGIDQE
                     DLYTGEKEFKITGILNSNPILKAQGTSIGLISNDCAIKNIPTKNKYDQIMFTFKKEKN
                     IQRQSQKLIKNGNLNENNIYFNNELLIAISDSMNLKIPYIIVNIVLALATILLIYNIF
                     YILVSNRIKDFGIFRALGFNPNDIFKIMILEVSIYSIISISIGLILGGIIASLSREYV
                     IGVIYNVNYINSIKNQNYINTYIISILLSLGTIIISVSKPLMLSVKTDPMICIRRNNE
                     KVDIKQNSFINKFMIKLFKDYGNIASKNIQRNKKRTNLSIASMVIIFFLMATIYTKST
                     SNFLSDGVLKYWIQGDYLLHNIDISTIRSNNKGYDKNVLQEIKAIDGVTKVNSYRHKW
                     FNIKIDDKSINKNSDYWKKNKDNIEARSEVKDGIKVYNNSFEFLGIEDTDILEDFLIN
                     GKENIDKFSKQPYLYITKKSSDSLNIKKGDRIKVYFDIIDSKTNNFTKTISQEFIVCG
                     IITTLPVTSQVGAEFGGVISTNQFNKFTGISSYERFDIWTSKLANDKYVESELNKITE
                     KTNKGILIPYKAETAEYEKIDNQKTLIMVLVTGIIVILSLFNCCNTIVTSINSRSREF
                     ALFRGIGISKHEINKIVKLESYIYIIVSFCISIIPILIVRSIIIKPFESINLINWKFI
                     GAIILIVFILVSIIMITTLKTLNKIQNENFMEEIKTL"
     gene            5397..5741
                     /locus_tag="PC465_000152"
     CDS             5397..5741
                     /locus_tag="PC465_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647489.1"
                     /translation="MYCLSVVLVIYGIYVFINCTEYIYTMLSTKQLTVTGNEYTIINY
                     YMSNFSQYIIFAILLASMGFVIQKIVHMHFSEIELSGNYSTTVRNISDISLDNDNEMF
                     NRGSIENSILKK"
     gene            5979..6665
                     /locus_tag="PC465_000153"
     CDS             5979..6665
                     /locus_tag="PC465_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2647490.1"
                     /translation="MSSILLVEDDLSLIYGLEYSIQKNGFSVDVARTVEEALQIYKEK
                     NYDLLLLDVSLPDGDGFDICKRVREASNVPIIFLTASDEEVNVVMGLDMGGDDYITKP
                     FKLNELISRIKALLRRYNFTSENVTELKSNNITVKLLENRVFKNEIELELTTAEYKLL
                     CLLMKNKNIVLTRKNILDKLWDGNGSFVDDNTLSVYVRRLRNKIEDNPENPKNLLTVR
                     RMGYKWNVIK"
     gene            6676..7917
                     /locus_tag="PC465_000154"
     CDS             6676..7917
                     /locus_tag="PC465_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2647491.1"
                     /translation="MKVFSNKDIKIFFLVIISVLLMFIVVGQIVVINITNDYKSALLE
                     HDYNIAGYLNSMGVDKSKIPAVFTTNEDKYTLKGKEILNTARYDFGTDDSFMPSVKLF
                     QGKYIKTMFLYLFVFFTMIIFILYVYFFRQQNKIEEASYKIDSFMNGNINVRLNTYEE
                     GSLSKLFGSIDAMSTSLNTHILKEKQNKEFLKNTISDISHQLKTPLTALMMYNQILQE
                     ESHNSEIVENFVQKSQNELERIESLIQNLLKITKIDSKTIILNKASVNVKKLITKILY
                     SFETRAEKEGKSISIRGLENTNLFCDYEWISEALSNLIKNALDNTKENDKIMIEWVET
                     PITTIISVSDTGNGIHIEDIHHIFKRFYRSKFSKSNQGLGLGLPLVKSIIEQHNGTIT
                     VESNFLQGSTFTLSFLKLTNM"
     gene            7988..8671
                     /locus_tag="PC465_000155"
     CDS             7988..8671
                     /locus_tag="PC465_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2647492.1"
                     /translation="MDILVVNNLCKTYGNGYTKVEALKDVSFTVSKGEFVTVVGESGS
                     GKSTLLNLLGGLDTPTSGKIFVDGKEICSMKEEKQTIFRRRNIGFIFQSYNLIPELTV
                     EQNIIFPLLLDYKKPDTIYLDEVLTILGLKDRKSHLPNQLSGGQQQRVAIGRALITKP
                     SIILADEPTGNLDSKNSSDVISLLKVTAEKYNQTIIMITHNTNIASTADRILQVSDGM
                     LKDLGVNRE"
     gene            8668..11001
                     /locus_tag="PC465_000156"
     CDS             8668..11001
                     /locus_tag="PC465_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2647493.1"
                     /translation="MRSYLELVPQYAKVHKKKNRTTILCIVIAVCLVTAIFGLADMAI
                     QCQKVQFIKDDGNWHIVLKNLNEEAISEISSRVDIAHYGRGQVIDNGEFKSKEILIQG
                     LDEDLAKQLGLEIIKGRYPVVENETLIDVDAVKSFNLKVGDFIKIKLADGRNKNYKIV
                     GEYSSLSSLRASDKHGLMLSILGTQAIKKSETYDYYYITFKDKVNIRKATSDIKNTFN
                     LSDKQIGKNEKLLSIIGQGDSDYSKPLYLTAGGLFILVLIASIIMIYNSFNMGVIERI
                     KFFGLLRCLGASKLQVKKFVVLESLILSVKAIPLGLLLGCIVTIISSIFLKYVNTELF
                     GSMPILKVSFIGIVFGIIVGFLTVILSAIVPAKKASGVSPLSAIRGNLMFKEILTSGK
                     ASKIANAGSSKIDVSMGINHAFSRKKSFILMTSSFAISIVLFLGFSVFIDFMYQALKP
                     IKPEATHISIVDADFKSVLTKDDINEISNIKGIKKVYSRMMTDVEATYNNKEATSQLI
                     SYEKNQFDWAKKYLVKGEINEDKLESENIGLVEEGHGFNIGDKIYIKNGNSKKEIEVA
                     GILSSISFDVKDKYIGNIITSENTFTSITDIKDYIIIDTQVDEDAPEDLIQNIRNVLD
                     DNLEVRDKRQGNLEAKNSFYTMAVFVYGFVFIIAIISMFNIINSMNISVTSRINYYGI
                     MRAIGMSNKQLRKMVIVESSTYAVSGCLLGSVLGLILHRYIFVSLVTLKFHIDWQIPF
                     DLLFIIVVTMIIITLLAVRKPIKKICELDIIEVVNAQ"
     gene            complement(11109..11671)
                     /locus_tag="PC465_000157"
                     /pseudo
     CDS             complement(11109..11671)
                     /locus_tag="PC465_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901678.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(11785..13134)
                     /locus_tag="PC465_000158"
     CDS             complement(11785..13134)
                     /locus_tag="PC465_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2647494.1"
                     /translation="MEKAKKLGLFSMILLGINSIIGSGIFLLPGKVYNLAGQNSMFIY
                     IFATLLVLSILLCFAEVGSMFDKNGGAYLYSKKAFGDFIGFEVGTMSWVIRIISWSTL
                     AVGFATALGSFWPESATEYKGYIAAILVTLLSINSLFGIKSTKIMNNVITIAKLVPLI
                     VFIIVGIFFIKFVNIVPSGNVVNSSMGPAIILVFYAFTGFESFIVASGEMENPKKNLP
                     VALITTIFICAIIYILIQIVCMGILGDRLFENSIPIADASSVFLGNYGKVFISVATLI
                     SIFGINIGSSIVTPKCGSSLAEEGSLPAFIGKTNKYGAPYVAIIISLICCIPLVLTGS
                     FEQLAVMSVIARFAQYIPTCLSVIVLRKRTDVKASFKIPFGPVIPMVAILGSSWLLQQ
                     AWAEDISKPITQNRVLIGLGAMLLIAPLYIFMKKNKEIEHKNKSEDSKLYISREKIQ"
     gene            complement(13171..14391)
                     /locus_tag="PC465_000159"
     CDS             complement(13171..14391)
                     /locus_tag="PC465_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2647495.1"
                     /translation="MQQALKLKYQTKELGKDFVIESCNSIKPWLINIRRELHKIPELA
                     LEENLTKQKVISYLKEIGIDYMEFTKHNGIMAYILKESADKTICIRADMDALPIEEEN
                     NIPYKSIHSGKMHACGHDAHTTMLLGACKVLHSIKDKLNVNVKFLFQPAEEGFGGAKF
                     LVEDGCLENPKADYIFGLHVMPHIETGLIETKYDTLNASVDTIKISIKGKRAHGAYPE
                     NGIDAIVTASQIVTSLQTIISRNLEPNNAAVLTIGKIYGGDTHNVICEDVKLEGTLRT
                     LNSKTRNFMIDKIAKIVGDTASAFGCVGTLHVSDENYPAVINEKELVDTVISNTKELL
                     GEEKFILRPNPSLGGEDFSFYTEHCKGAFFHLGCKNEEKGLISPLHTSSFNIDEDCLP
                     IGVMMHVMNTLYFN"
     gene            complement(14760..16772)
                     /locus_tag="PC465_000160"
     CDS             complement(14760..16772)
                     /locus_tag="PC465_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2647496.1"
                     /translation="MKKSVALVNDSRKDLIDFLENNLKLVFGDSININRYFINEINDN
                     DIINDDVILVMSVERLDKIINNILDKKKVIVVRRTFREDKIYNLLSLPQGTNVLIVND
                     SDETTLETISLFYKIGVTNIRPIPYMNDNNYKNIKIAITPGVPEKVPSFISDIFDLGH
                     RYIDISTFIEIINLLQIDSKEIQSNLVKYSEEIISLDTGIKDKYKELFLKIEELDTIL
                     NLSKDGILFTSKDGEINTYNSKVKDILDINEDIYGKYIEDIFVDSLKVLLSEKEILDK
                     VVVFNKKYINVNKKNIYNRDEKMGTYYSLQEITYIKKLEQNLTKKLREKGQIAKYTFK
                     DIKTNSPKMFECIDLAKKVSKSDLSILIRGESGTGKELIAQSIHNNSNRKNQPFIAVN
                     CAAVPENLLESQLFGYDKGTFTGGLKDGKQGLFELANNGTIFLDEIGDMPLELQTKLL
                     RVLQEKQIMPVGSHNVINIDVRIISATNKNLEQMIDNSQFREDLYYRLNTIPINIPPL
                     RERKEDILIIMEDLINKKLIITPEAKKLIQNYMWKGNIRELQNVTSYLNIMCEDIVLE
                     KDLPPNLRSSDNKNTSLKLKYSKNDILNILEILILNKESDVGIGRGLILKALLDKNLQ
                     ITEGKIKKIFEYLKKEELIICSSGRYGSKITQKGEDFYNKLKYKGL"
     gene            17243..17893
                     /locus_tag="PC465_000161"
     CDS             17243..17893
                     /locus_tag="PC465_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HDF2647497.1"
                     /translation="MKAEKTSIYPIIKNNLNKISIVEYKKGQRFVASDKDLQEVFFII
                     EGVALVECTTRGGNKFLVDIVPENEFIGKISYIYEHNLKCDIFAKTNIKLFRFEKNVF
                     EEFYLKPDFIALFHRKCTRRIYELYKTRMVRELFSCTEVIAYCISNKQENNVCNIKAI
                     RNFSEIYSISRKSRYHSLLKLTEKEIVKKMGNTYEILNYDELHKLAFEVKEFLEDE"
     gene            complement(18033..19409)
                     /locus_tag="PC465_000162"
     CDS             complement(18033..19409)
                     /locus_tag="PC465_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2647498.1"
                     /translation="MQELFSLKDENKRFYKILLSLCIPIIIQNLISTSVNVIDTIMIS
                     SLGETSVASVGVANQFFFLFNMSLSGITGGAGVFISQFYGKKDVSNIRKVTGLTCVLA
                     IVLSFVFVIPALLTPKPIIHIFSYDSEVVKLCIDYFSIAVFSYPLIAVSTVFSTGSRG
                     VRNPKLGMICSAFALVTNVILNYGFIFGNFGLPALGVKGAALATVIARICELILMITY
                     VYLYKKDYILKFGLKNLKAIDKIFIKSFSSKSFPIFVNDSVWAIGTVLYSVAYARAGT
                     SAIAASQIATSTGNFFIMTAVCIASGASIMLGNELGADHIKRAIEYAKKFSILVFSAG
                     LILGIILILNIPLLLKMFSVSDSLASDITKIFFIMGILMALKSFNTLVIIGILRSGGD
                     TKYALFLELGCMWLASIPLTFIAAFKGAPIFVLVLLTYSEEVVKFIFGVPRALSKKWA
                     INIVKEID"
     gene            complement(19425..21338)
                     /locus_tag="PC465_000163"
     CDS             complement(19425..21338)
                     /locus_tag="PC465_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2647499.1"
                     /translation="MIVLSCNNLNKSFGIDSILENISFTVNEGDKIGIIGVNGTGKTT
                     LFKIISGIYGYDSGDIYTSKDCEIGYLEQNTNFYSDNTILEEVLEVFKNLIEMESYLR
                     ELEVKISEESTKTNSPIIEKIMDEYSHKLELFSDLNGYGYKSEAKGVLKGLGFSDNDM
                     DKPISILSGGEKTRVLLGKLLLKKPTLLLLDEPTNHLDSEAIEWLEVFLKQYKGTVML
                     ISHDRYFLDQSVNRIFEVHNKKLKVYNGNYSKFVELSKIEKELELKKFEDQQKEIKKQ
                     EESIERLKAYGREKHLKRARSKEKALDKVDVLDKPEAYRKKARIQFTPSVQSGNDVLQ
                     IRDVSMGYGERILFKDLDLDIYRGEKVALIGANGVGKSTLFKIITNELQPLSGNIKFG
                     TNVHVSYFHQEQKTLNLDNTIIDEIWENNTHLTQTTLRNMLGAFLFVDEEVFKKISTL
                     SGGERARVAILKLILSNANLLLLDEPTNHLDIDSKEVLEEALTNYDGTIFTISHDRYF
                     LNTVVDKILVLDENGITEYLGNYDYYIDKKRQIQEMSIIEEKEEKTRTQIKDEKRKER
                     EQREIEKKNRIKRQNIEKEIEKLEIEIEKLDILLCQEEVYSNPDKAKEVSQEKINLEN
                     NLASLYDEWEEFM"
     gene            21474..22106
                     /locus_tag="PC465_000164"
     CDS             21474..22106
                     /locus_tag="PC465_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HDF2647500.1"
                     /translation="MLGNKNISMAVIRRLPKYHRYLGDLLDRDIQRISSKELSDIIGF
                     TASQIRQDLNNFGGFGQQGYGYNVEALHTEIGKILGLDRPYNAVLVGAGNLGQAIANY
                     AGFRKAGFEIKALFDANPRMIGLKIREFEVLDSDTLEDFIKNNNIDIAVLCIPKNGAQ
                     EVINRVVKAGIKGVWNFAPLDLEVPKGVIVENVNLTESLFTLSYLMKEGK"
     gene            22245..22784
                     /locus_tag="PC465_000165"
     CDS             22245..22784
                     /locus_tag="PC465_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HDF2647501.1"
                     /translation="MVFVEELWKKAIEFHGHECPGLAIGFKAALAAKKYLGCKQSGDE
                     EIVCISENDACGIDGIQVVLSCTMGKGNLLLRMTGKSVYHFFNRENGKSIRIYVKSKP
                     FEMDREGYKRYLLESDFEEIFEITDTKLRLPEKARIFKSLKCEVCGEFASEQYIRIEE
                     GKKVCLDCFDKYERFYEEY"
     gene            complement(22960..23130)
                     /locus_tag="PC465_000166"
     CDS             complement(22960..23130)
                     /locus_tag="PC465_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004619190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2647502.1"
                     /translation="MAYKITDACISCGACEAECPVSCISAGDDAYVIDAGSCIDCGSC
                     AGACPVDAPQPE"
     gene            23415..24482
                     /locus_tag="PC465_000167"
     CDS             23415..24482
                     /locus_tag="PC465_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HDF2647503.1"
                     /translation="MKNKLVYICIMSLLLFVVGCSNNPNKESTIKKDSKNNQSQVKEE
                     KREPVKKDITISFAGDVTMGNYKGSSYYGSFDHEFKRQGEDYNYFLKNVKPVFEKDDL
                     TVVNLEGPLTTASNAKEKKFAFKGKPGYVNILKSGSVEAVSIANNHSEDYFEEGMKDT
                     QFILDENKINYFGLGKDAVVDVKGIKVGLLGYNGLSTEYNEKNLKQMEDDIKSLKKKS
                     DVVVVYFHWGIELDYYPDKKQKDFAHYAIDKGADLVMGSHPHVIQGIEKYKNKYIAYS
                     LGNFCFGGNKNPSDTDSYIYQQTFTFSDNKLTSIKEPNIIPTSITSSNSRNNYQPKVL
                     DGSEKDRVLNKLEKISKDLNK"
     gene            24652..26553
                     /gene="cooS"
                     /locus_tag="PC465_000168"
     CDS             24652..26553
                     /gene="cooS"
                     /locus_tag="PC465_000168"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HDF2647504.1"
                     /translation="MACNTCKMCESADKKLESFVASKDVETAFHRTEDQKVKCGFGLQ
                     GVCCRLCSNGPCRVTPKSPRGICGADADTIVARNFLRAVASGAACYLHVVENTAKNLK
                     NVGITKGVVKGEKTLNQLAEMFGIESDEKYDKCIKVADKVINDLYKSRDDKMELVEKI
                     AYAPRVKKWKELGIMPGGAKSEVFDAIVKSSTNLNSDPVDMLVNCLNLGISTGLYGLT
                     LTNLLNDVMLGEPVIRMAPVGFNVIDPDYINIMITGHQHSTFANFQDRLKDEDVIKLA
                     QSVGAKGFKLVGCTCVGQDLQLRGEHYQEVFAGHAGNNFTSEAVLSTGAIDIVLSEFN
                     CTIPGLEPIADKYKVKMVCLDDVAKKANAEYIGLDRSKLDELSNTLIEKALESYKERR
                     GSIEIDIPKDHGFEQSLTGVSEKNLKAFLGDSWKPLINLIAEGKIKGVAAVVGCSNMT
                     AGGHDVNTVELTKELIKKDIIVLSAGCSTGGLENVGLMSPGAEELAGENLKEVCKTLG
                     IPPVLNFGPCLAIGRLEIVATELAAELGIDLPQLPLVLSAPQWLEEQALADGAFGLAL
                     GLPLHLALPPFITGGKLVTEVLTEKLKDLTGGHVIVNPDPKSSANQLEEIIIDRRKNL
                     GLKDVECNA"
     gene            26546..27019
                     /locus_tag="PC465_000169"
     CDS             26546..27019
                     /locus_tag="PC465_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2647505.1"
                     /translation="MHRIFINKDLCTGCKSCVLACMLKHNKDYDMYTLDLENIDNDSR
                     GHIELDSKHNNPVPILCRHCDEPECVLACMSGAMHKDSESGIVSYDEEKCGSCYMCVM
                     SCPYGLLKPDDRSKQNILKCDLCKDEEYPRCVANCPSGAIELQKEENDELCSVRS"
     gene            26994..28220
                     /locus_tag="PC465_000170"
     CDS             26994..28220
                     /locus_tag="PC465_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2647506.1"
                     /translation="MNYVVLGASAAGINAVKTLRELDKDSNIVVISKDENVYSRCMLH
                     HVISEHRTLKQINFVDEDFMEQNNVKWIAGKTVKGIDINKKVVQTEDITVNYDKLLIA
                     TGASSAIPPIKNLRDGNFVYSVRNIDDIYKIKEKAQNSKNVVIIGAGLVGIDALVGLF
                     KYEQLNISVAFMEKYILDRQLDEYTASVYENKFKEKGVKFYPSASIQEIVLDNSKNVT
                     GVAFSNGEVLDADMVIVATGVKPNADFLDGTGIEYDRGIIIDDMCQTTQKDIYAAGDV
                     VGKNAIWPLAVKQGIVAAYNMVGKDKKIEDEFAFKNSMNFMDIPTISIGMNTPVDDSY
                     KVLTRHGINDYKKFVFKDNVIYGAVIQGDISYVGVLTYLIKNKVEIYDLENRIFDICY
                     ADFFNIKENGEFCYSV"
     gene            complement(28359..29546)
                     /locus_tag="PC465_000171"
     CDS             complement(28359..29546)
                     /locus_tag="PC465_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2647507.1"
                     /translation="MNITKNFLKDYLERFGETPFLVRLKDEEEFLIGEGSPQFKVIVN
                     NDISKSELLKSTSLALGEAYINRDIEVEGDLFLTLNLLLKQIDKFNIDNSAVKHLLHS
                     SNSMRHQKKEIHAHYDIGNDFYSLWLDKTLSYSCAYFRNDNDTLYDAQVNKVHHILTK
                     LNLEEGMSLLDIGCGWGFLLIEAAKKYKIHGVGITLSEEQFKEFNTRIKEENLQDYLE
                     VRLMDYRELKKSDLMFDRVVSVGMLEHVGRENYELFIKNVNAVLKDGGLFLLHYISGL
                     QESYGDPWIKKYIFPGGVIPSLREMIHICSDYKYHTIDVESLRLHYVKTLLYWQKNFS
                     ENLPKIKEMFDDKFIRMWDLYLCSCAAAFNTGIIDIHQILFTKGIKNDLPLTREYMYN
                     CSK"
     gene            29821..30645
                     /locus_tag="PC465_000172"
     CDS             29821..30645
                     /locus_tag="PC465_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2647508.1"
                     /translation="MEVYALVGSSGTGKSFKALEFAYENDIEYIIDDGILIYKNKVLA
                     GISAKQANTTIEAVKRAIFYNLEHREEVREAIKKENIRKILIIGTSKKMVNQIVERLS
                     IGRVCKFINIQDISTKYEIEIAKQARKEGNHVIPVPAVEIKSMASGLSINSLKRLFRK
                     GNNRNMVVLEKTIIRPTFSYIGKFYISADVIKQIIEYEVYNFGSIDRINKINIENCNN
                     FMNIFVSININDLETIKKIEDIQQTIKKSIEKMTLVNVQKIDINIHKIKKINFLQC"
     gene            30774..32039
                     /gene="gluD"
                     /locus_tag="PC465_000173"
     CDS             30774..32039
                     /gene="gluD"
                     /locus_tag="PC465_000173"
                     /EC_number="1.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-specific glutamate dehydrogenase"
                     /protein_id="HDF2647509.1"
                     /translation="MSGKDVNVFEMAQSQVKNACDKLGMEPAVYELLKEPMRVIEVSI
                     PVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWMTFKCSVTGIP
                     YGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNGQIMSWMVD
                     EYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKKAKIAVQ
                     GIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHGNLLN
                     FPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADEVF
                     AERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIK
                     EEYNVTMREAAYMHSIKKVAEAMKLRGWY"
     gene            32252..32365
                     /locus_tag="PC465_000174"
     CDS             32252..32365
                     /locus_tag="PC465_000174"
                     /inference="COORDINATES: protein motif:HMM:NF017390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647510.1"
                     /translation="MHFKSKDFHLKYLVLFLKIVYWFNPFIYNGKIYGFGL"
     gene            32349..32840
                     /locus_tag="PC465_000175"
     CDS             32349..32840
                     /locus_tag="PC465_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HDF2647511.1"
                     /translation="MDLDCEFYCDERVLKNCTVQQKQEYALTIVNSMKRGTNFSNKFV
                     AGLNKQSDIRKRVINMFSEKYKNGILMALIISLFSSITFFKFDSTSIIEENDFLERSR
                     YTFEGRQEDVFVTIDFIYADAPIKLRKEHEENCRVNGIVPKDSDSIEIIPRFYKDCMD
                     LKK"
     gene            33170..34309
                     /locus_tag="PC465_000176"
     CDS             33170..34309
                     /locus_tag="PC465_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HDF2647512.1"
                     /translation="MSNFILNGIFRTVIVSSLSILMILIFKKNVFKRFSKKFNYYIWM
                     IVVIKLFLPFTYYTFTINILRSKKHININNINLEGFNNVSTISNNIILYTWIITVVVY
                     LIYTIFKYIKLKNLINDLSYDVDDGEIVNLYKNILEEFNITKDIKLKYSYEVETPAFF
                     NSCVLLPPHEYKLKELDWIFRHELMHFKSRDLYLKYVILFLKTVYWFNPFIYIMDKHI
                     DLDCELYCDERVLKNRNSDEKKDYALTILNAMRKGSNTSNKFIAGLHKQSDIKKRVMN
                     MFNEKYKNGILMALTLCLLSSITFLKVNSTSIVNLNILPKYDMEKLHVFRGSVTLLEF
                     TYADAPENVKKEHKRMYEAMGLIPKDSDKISFGVKYYDKLNNLLR"
     gene            34780..35802
                     /locus_tag="PC465_000177"
     CDS             34780..35802
                     /locus_tag="PC465_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2647513.1"
                     /translation="MKKKILIPVFASVMALSVSSIVNADEVNDSSQNKDDKTNTELNL
                     GEYKEVKYKVAKIKDGVAIKIREEGQVQNIAYSGDEFTVLGTQGEWVKVKVEDGEGWL
                     ATRYVDISEGVGYTNADKVNLRKDKSESSEVIEELEKGSSLLVLEDNGDWLKVKDGET
                     EGYVKSSYISDKAPVIEEPQVNPSIDQNVDSTNNNQQNNANTNQQNNNSNVPTANSNA
                     VQAVLNLAYSKQGCPYVWGAEGPNTFDCSGFTQYVYRNAVGKNIPRTSKAQSKYGQTV
                     SKANLQPGDLVFFTTNGSGSVSHVGIYVGGGNMIHSPSTGKTVSVTSINSSYYTARFV
                     TAKRIL"
     gene            36098..37018
                     /gene="pyrB"
                     /locus_tag="PC465_000178"
     CDS             36098..37018
                     /gene="pyrB"
                     /locus_tag="PC465_000178"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HDF2647514.1"
                     /translation="MLKSRNLIQPEDFSIEEIDEILELAQKIIDNPSKYSRICEGKLL
                     ATLFYEPSTRTRLSFESAMNRLGGRVVGFSEPNSSSASKGETLGDTMRIVSGYVDIIA
                     MRHPQSGAASEAARYTEVPFINAGDGKNQHPTQTLTDLLTIKSLKGTLESHTIGLCGD
                     LKYGRTVHSLVKAMARYKNTKFVFIAPEELKMPDYIKEAIKGHAYYETNNLDDVIGSL
                     DVLYMTRVQQERFEDKSEYERLKNYYILNKAKLEKASKDMLVMHPLPRVNEIDIDVDS
                     DDRAVYFKQAKYGMYVRMALIIKLLGINED"
     gene            37057..37749
                     /locus_tag="PC465_000179"
     CDS             37057..37749
                     /locus_tag="PC465_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HDF2647515.1"
                     /translation="MYKILENIYIGEDMYRMKVKGNFEGKMGQFYMLRAWDTYPVLSR
                     PISIHDIDEEGITFLYKVVGEGTQILSNLKVNDNIKLEGPYGNGYAKVDGKVALVGGG
                     IGVAPLYLVAKNIKNCDAYLGFREDVILEDEYKQVCNKVYTTVGNTFVTDIIDVEKYD
                     YILTCGPTPMMEKLVKMVEGTKTRIMVSLENHMACGVGACLVCTCKTNGGNKKTCKDG
                     PVFWGEDVIFNG"
     gene            37742..38644
                     /locus_tag="PC465_000180"
     CDS             37742..38644
                     /locus_tag="PC465_000180"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HDF2647516.1"
                     /translation="MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISS
                     KGLTLNKKPGNNGMRVHETPSGMMNSVGLENPGVQGFIDYELPFFSKLDLVRIANVGG
                     GTLEDYLLGVQMLNDKPIDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLP
                     LVIKLSPNAEDIVGMAKVCEEEGADGVSLVNTFKAMAIDIKNRRPVFENVYAGLSGPA
                     IKPIALRMVHEVCKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFMNPRIGIE
                     IIDGINEFMDREGIKSLDEIRGII"
     gene            38729..39313
                     /locus_tag="PC465_000181"
     CDS             38729..39313
                     /locus_tag="PC465_000181"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HDF2647517.1"
                     /translation="MSKVDVVDILKKSDALLEGHFLLSSGKHSNRYVQCAKVLRFPEY
                     AAEVLSTVVEQIKDLDIDLVVGPAMGGVIVSYELGRQLGKEAVFTERKDNTMELRRGF
                     EVKKGAKIIIAEDVVTTGKSTMETKRVLEALGGEVVGVACIADRTNHDIGMPIYSAIK
                     LDIQVYESDECPLCKEGKLPVVKPGSREFKELGM"
     gene            39528..40454
                     /locus_tag="PC465_000182"
     CDS             39528..40454
                     /locus_tag="PC465_000182"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HDF2647518.1"
                     /translation="MKNQLNENHKKVVFFGVGAVGATFAEQFFNSKYDFKILCDNERK
                     KRYLEEGFIINGKRYDFDYVTKDEYKQEADFIIIGLKYNNLKENIKELDGLVGKNTVI
                     MSLLNGVDSEEIIGERFGIEKMVYSYVTNIDAKKINNNIIHTTNGIIVFGNKDNSEDR
                     KTNIITEVFDDVNIEYTLSKDIQRDMWWKYMVNIGVNQTSAILGAPYGVFQSSEHLRE
                     LAKSAMREVVAIAQAKDISLTEDDVEHSLHRILEHSKEGRTSMLQDVEAHRLTEVDMF
                     SKNICKLGKKYNIPTPINQTFFYMIKVIESRF"
     gene            complement(40506..41396)
                     /locus_tag="PC465_000183"
     CDS             complement(40506..41396)
                     /locus_tag="PC465_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2647519.1"
                     /translation="MFEELKTFVAVVEYKNFTKAGEYLNLSQPSVSKHIKNLENYFKV
                     VLINRSIKQKTIFITESGQILYKRAKEILNLLNITYHDVSQVSDAITGHLKIGASLTI
                     GEYILPNFLALFSKKYPDIDVEVFIKNTSIVSSHVKDYILDIGLIEGTCSSPSFIQEY
                     FFEDKMVLALPYKSHLLKDFSFDKLQNQKWIVREDGSGTRDYLDMFLSVKEIIPKSMM
                     VFGSNYAVKESVRNNLGITIVSNLVTSLPVLNNELSVIELGSSYNRHFSYIFPKDITL
                     SKAATIFIEELKIFSNLNSI"
     gene            41584..42615
                     /locus_tag="PC465_000184"
     CDS             41584..42615
                     /locus_tag="PC465_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HDF2647520.1"
                     /translation="MLKKKSSLTLKTIREILPGLFVSVLVGYISIFISILIPKVGAAS
                     ISIFLGMFVGNLFLNQKVFQKGYKFSETDLLSYSIVLLGATLSVSTLIDLKVSGILFI
                     ILQMTITIIAALYIGKKLGFEENFRFLMASGNAVCGSSAIGATVPVVNATDKEKGIAV
                     TIVNVTGIFLMFLLPIISQFLYSHELVKTSAMIGGTLQSIGQVVASGAIVGENVKDLA
                     TIFKIVRVIFLVVVVLVFGHMKNQSNREILEEEKDEIKKKKVTIPWYVIGFFITCALF
                     SMNIIPKEVSVLCKEISNKLEIIALAAIGLKVNVKDLVKQGKEVSLYGLFVGTVQVVS
                     AVVLIKIFI"
     gene            42909..43784
                     /locus_tag="PC465_000185"
     CDS             42909..43784
                     /locus_tag="PC465_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxoguanine DNA glycosylase"
                     /protein_id="HDF2647521.1"
                     /translation="MNVYEKGNGVILERVTDFDPVHIFECGQCFRWHKQEDGSYTGVA
                     KGRILNVKKENDKIYLNNTNLKEFNSIWYNYFDLGTDYTEIKNKLKNMDEYLNKATEF
                     GWGIRILRQDGWEMLISFIISSNNRIPMIQRAIENLSRKFGKYIGEYEGNEYYAFPTP
                     EELNKASQEEIRACQTGFRDKYIKSTTQAVIENNDEVSEYTNLSTEDCRKELLKFNGV
                     GPKVCDCIALFGMQKYDSFPVDVWVKRVMQEFYIDEDMSLPKMRTYGIDKFKEMSGFA
                     QQYLFYYARELGIGK"
     gene            43802..45292
                     /gene="cls"
                     /locus_tag="PC465_000186"
     CDS             43802..45292
                     /gene="cls"
                     /locus_tag="PC465_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDF2647522.1"
                     /translation="MGVIGTIFLFYLIISYLAGAIISVIILLENRDPAKTMSWLLMFI
                     IFPGVGLMIYAISGRNIRKRKLFKTQKLANNIKEKKLFDTLEKITEIVELEKESIKQN
                     KLLRDEEDGSYRKRVINMLLKTGMFPFTKNNKVDVFVDGNEKFKRLIEDIREAKDHIH
                     LEYFIIKDSEIGRVLKEELIKKAKEGIKIRILYDDVGCWRFWFNRKFFREMREVGIEI
                     AAFLPTKFPIIGGKLNYRNHRKIVVIDGIIGYTGGINIGDEYLGKNDKFGYWRDTHIR
                     IKGISVYMLQMTFLIDWYYTTKEVLVTKNYFPSVGNVGESMIQVVASGPDSDWEDIHY
                     AYFSAICQARKNVYIETPYFIPDESLLKAIKSAALSGVDVRIIFPKIADHKIVNIASY
                     SYFEEILRAGGKVYLYNKGFIHSKVVIIDDKIASAGTANMDLRSFMLNFEVNAFIYDE
                     EVIRVMTDDFFEDLSHCEELNLEVFKNRNIIQKIKESVARLFSPIL"
     gene            45485..45769
                     /locus_tag="PC465_000187"
     CDS             45485..45769
                     /locus_tag="PC465_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012062101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HDF2647523.1"
                     /translation="MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVG
                     PGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE"
     gene            45802..47430
                     /gene="groL"
                     /locus_tag="PC465_000188"
     CDS             45802..47430
                     /gene="groL"
                     /locus_tag="PC465_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729227.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HDF2647524.1"
                     /translation="MAKEIKFSEETRRALEAGVNKLADTVKVTLGPKGRNVILDKKFG
                     SPLITNDGVTIAKEIELEDRFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREG
                     LKNVTAGANPILLRKGIQKAVTVAVEELKNQSRIVETQEAISQVASISAGDEEVGKLI
                     AEAMEIVGKDGVITVEESQTMNTELDAVEGMQFDRGFVSAYMVTDVDKMEAVLNDPYI
                     LITDKKISNIQELLPVLEQIVQQGKKLLIIAEDVEGEALSTLVVNKLRGTFDVVAVKA
                     PGFGDRRKEMLQDIAILTGAQVISEELGYDLKEADLSMLGRASSVKVTKESTTIVDGS
                     GDKKAIEDRVTQIKHQVEQTTSDFDREKLMERLAKLAGGVAVVKVGAATEVELKERKL
                     RIEDALNATRAAVEEGIVAGGGTAFVSVIPAIGTLIESLEGEVKLGAQIVKKALEEPL
                     RQIAINAGLEGAVIVQNVVNSEAETGFDALNEKYVNMIEAGIVDPTKVSRSALQNAAS
                     IASTFLTTEAAVADLPEKEDAGMPGMGGGMPGMM"
     gene            47692..48432
                     /gene="larB"
                     /locus_tag="PC465_000189"
     CDS             47692..48432
                     /gene="larB"
                     /locus_tag="PC465_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HDF2647525.1"
                     /translation="MDLRKLLEEVKNENIDIDFALEKLKDLPYEDLGYANIDHHRELR
                     NGYPEVIYCEGKSDEHILGIIDKMNQKSSNILGTRCRKETFLKIKEIYNHAEYEEVSK
                     ILKIQNHDIENIGKGKIVIATGGTSDIPVADEAYHTAKFLGNDVDRIYDVGVAGIHRL
                     LNKRHKIDSARVIVAVAGMEGALASVIGGLVDVPVIAVPTSVGYGANFGGLAALLAML
                     NSCASGISVVNIDNGFGAGYLASMINKL"
     gene            48516..49250
                     /gene="larC"
                     /locus_tag="PC465_000190"
     CDS             48516..49250
                     /gene="larC"
                     /locus_tag="PC465_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
                     /protein_id="HDF2647526.1"
                     /translation="MSEKILYFDIISGISGDMTLASLLNLGVPKEIFLEEIHKLRMSD
                     EFNINISSKTENGIVGTKVEVITKEKHTHRNLVDIFEVIDKSTLNENVKFKAKKIFMV
                     IGEAEAKVHGTTIDKIHFHEVGAIDSIVDIVGASILVDLLCVDKVCASTVSVGSGFVK
                     CEHGIIPIPAPATIEILKGVPIKLNNVNGECTTPTGAAIIKVLCDEFVDELEFSPKQI
                     GYGIGHKKFEVPNILRTVLGEKKKKN"
     gene            49280..49699
                     /locus_tag="PC465_000191"
     CDS             49280..49699
                     /locus_tag="PC465_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF111 family protein"
                     /protein_id="HDF2647527.1"
                     /translation="MSSEIYSYLYEKILDEKALDIYTESIYMKKNRPATKVSILCNES
                     DLEKFIKILLLETSTFGVRYNAYNREILERKFVKLDTKYGVVTVKLGYYKGKLVKATP
                     EYNECKTIAKNEDIPIKKVFADINFRIKEEFSENLLT"
     regulatory      49759..49860
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            50081..51616
                     /gene="guaA"
                     /locus_tag="PC465_000192"
     CDS             50081..51616
                     /gene="guaA"
                     /locus_tag="PC465_000192"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HDF2647528.1"
                     /translation="MKHELVLVIDFGGQYNQLIARRVRENNVYCEILPCTASIERIKE
                     KNPKGIIFTGGPNSAYLEDSPTISKEIFELGVPILGICYGIQIMSHVLGGVVRKGNKQ
                     EKEYGKTAITYGKSSLFEGITTNSVWMSHTDLIEKVPEGFTIVANTNDCPVAAMENVE
                     RNLYGVQFHPEVEHCLEGDKILTNFLYNICKVKGDWTTDSFIEDKIKELKEKIGDKKA
                     LCALSGGVDSSVAAVLIHKAIGDNLTCIFVDHGLLRKNEGNDVERIFREKFDINLIRV
                     NAEDRFLSKLKGVSEPEAKRKIIGEEFIRVFEEESNKLGKMDFLVQGTIYPDVIESGH
                     GNAATIKSHHNVGGIPEDVDFQEIVEPLRELFKDEVRKIGLELGIEEGLIFRHPFPGP
                     GLGIRVIGDVTKEKCDILREADAVYMDELRKAGLYREIWQAFATLPDVKTVGVMGDER
                     TYAYLVGLRAVTSSDGMTSDWYKMPYDVLERISNRIINEVDGVNRVVYDITSKPPGTI
                     EWE"
     gene            52155..53585
                     /locus_tag="PC465_000193"
     CDS             52155..53585
                     /locus_tag="PC465_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2647529.1"
                     /translation="MILNQIFIEAGGIMRNKIIIGITFSLVLLMSGCASKQTAEINVL
                     ATTDLHGVIPYELTSYVKEERKKDKNLTLVDAGDFFDSGEVFGSSMDSYFSARYKDGD
                     NNTESYIETPISKDMKEVGYDVAVLGNHEFISNNKFYLDNMISDFEKQKINILSANTY
                     KKNGDSYTKPYIIKNINTPEGNVKLGILGLTIKEVGERKQWKDGKLVDSKSLELKDQE
                     GYNGELYMNDLVEDAKKWVSIMEKEKPDIIVAVAHTGEKPKKPRNPGNRIQDLAQQVD
                     GIDAIVAGHNHVQIEQHDYKNKSGENVIVTEPGKHGECISKINFKLEKNNDKWNIVDK
                     SSKLIKFEKNQESDKFGEFISSINKVSKDKKEIRLSEVKTPEWDKIYVFKSGTSADDI
                     YKTIGYKWRNISSPKGDDMVQIVVMNNNKPVSYVYGEAEVMPINIKCDESEYKDNVVT
                     IYPNKNDKFKIEKGKQEYSINLKHIQ"
     gene            complement(53733..54608)
                     /locus_tag="PC465_000194"
     CDS             complement(53733..54608)
                     /locus_tag="PC465_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2647530.1"
                     /translation="MINIRYLEILEAIEQTGTFTGAAKKLHITQSAVSHAIAELEQQA
                     ETALFDRLPRGVCLTRCGISLLEEARSILTACRNLDKRISHLEECTPINIVSSITIAS
                     FLLPPILSRLKNSFPSLKVNVRVESANSAMDILKSGEADICFWEGIEPQGAFRTILLG
                     SYKLCVACAPTFPLSKQALSLRQLCTFPLLLREQGSAIRDTLDSVLSLSNQKAYPVWE
                     SVNSFALIKAAEAGLGITILPENLLLDSLLHKKLRLIELDGIDMENKMLAILHKDKNI
                     TQPLKIILDNISNVL"
     gene            54728..55291
                     /locus_tag="PC465_000195"
     CDS             54728..55291
                     /locus_tag="PC465_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF2647531.1"
                     /translation="MNQSRKTYFWLLIINLFISTFTFGGGYVVVPMIRRYFVNQKQFF
                     TEDDLMSMAAVAQSTPGAIAINLSALAGYRVAGTLGVVISCIAAIIPPLVILGLVSAF
                     YTTFISNAIVIAVLKGMQAGVAALIVDLIIDMCSMILKQRSLFLSAMIPIAFFANFVM
                     SINVIFILSVCCFVCVMQVFYKKRENK"
     gene            55288..55854
                     /locus_tag="PC465_000196"
     CDS             55288..55854
                     /locus_tag="PC465_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF2647532.1"
                     /translation="MNTIWNLFFIFLKIGLFSIGGGYAIIPLIQEKVVNQTGWISEKM
                     FTDIITISQMTPGPLAVNTSTFVGLQIGGFWGAVAATLGCVLCGVVISLFLYNFFQKH
                     QNSTYIFEILNGLKSASLGLIISAAATIIILALFGTNKVYFNSIFEMLNWTALIIFFV
                     TLLIVRKWKINPIVIIIISGILGIFFYL"
     gene            complement(55983..56219)
                     /locus_tag="PC465_000197"
     CDS             complement(55983..56219)
                     /locus_tag="PC465_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647533.1"
                     /translation="MLECFIAEDSKIKDGVNIPTLVFKTLHDRYFKTQYFDSYYNSLK
                     CKKKLVEINNVHNSYYIDSEKFCQEAYDWFVENQ"
     gene            complement(56529..59957)
                     /gene="uvrA"
                     /locus_tag="PC465_000198"
     CDS             complement(56529..59957)
                     /gene="uvrA"
                     /locus_tag="PC465_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF2647534.1"
                     /translation="MKINNYKNQSIITNPKKFENKYQDLPKTPIELLKVVQSLVIHGD
                     QGKLYGISFNKQQSDEELLRTIPQMLKRIFEINSNPLTIPRNPKQRLVGMCRDYSLLL
                     VSLLRYRGFEARMRAGFANYFESELTYEDHWLVEYYDTLTKRWIRIDAQIDDIQKNYF
                     QINFDTHDVGKTDGFLTGSEAWIRCRQGHAHPDDFGYNKNWKGWHSVKGNLLHDFNNM
                     IGLELLPWDLWTELSSKKYNQLTRAEKNLLDEMAEILSIGNIKIEDLNLLIEKLPEDY
                     LKSIFSQLKILGISEIKELGNPLELEKKFKFTKSINKSIKNSLCHNKSSIYLKGGRQN
                     NLKDVEVTIPKNQITVITGVSGSGKSSLAFDTIYEEGKRRYFENLSNGAKLSEQLQKP
                     EFDLLQGLTPTIAIEQKKGSQNPRSTVGTLTSIWDYLRMLFVSIGKSYCPYCKIPLEK
                     KNNTKNYCPHCQTIFSKINTSTFNANSHTGACHDCNGLGFTYQVNPQLIVKDPTISIL
                     DGATYYFGKLRGKKPNGNWMVGELYAIAKDKNIDLDIPWNELPRDFIDAILYGTDDKI
                     YEFSFESKGRESKIRRPASGAINHIQRLFRESSSENNTLHQYMNKIPCNTCGGELLCI
                     EARFTTIKGYRFPELTKMTIEQLWNWLCELPNQLQKNELSLVNDILTELKIRVSYLLK
                     VGLSYISTDRTAPTLSGGELQRVRLSSQLGSELVGLTYILDEPSIGLHPRDHNLIIKM
                     IEELRDKGNTVIVVEHDKDTILSADYIIDVGPSAGTKGGFIIAEGTTQEIIKNPNSIT
                     GKYLSTYNKTGSQNKIIPSKWLSLKGCHANNLKNIDVEIPLNCMCSITGVSGSGKSSL
                     VFHSLLPALEEKLKQKSIPDKNYTEFTGFDAIDDFILMDQTPIGKSSRSTPATYINIF
                     DEIRSLFAETPQAKQKLLDESYFSFNSKKGQCPNCQGLGKTKIILQYMADQWVTCSKC
                     QGKRYQKEILSIQYKGKTIADILDMEVAEAKTFFSDCSDIYRKLSLLDEVGLGYLKLG
                     QNTLGLSGGESQRIKLAKELGTKTKKRMLYILDEPTTGLHFKDIENLLITFRKLVNEQ
                     HSLLIIEHNTEVIRASDWIIDIGPDSGINGGEIVASGTPDEIKINPNSITGHFI"
     gene            60276..62510
                     /locus_tag="PC465_000199"
     CDS             60276..62510
                     /locus_tag="PC465_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2647535.1"
                     /translation="MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSK
                     NYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDVGI
                     IDLEGKAEFLSGKKFDLKNTVSYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSI
                     LIGVSNKESMNEILNIDNFNGKGTIEIINSKGKPLFIGKNTELIKDLSHKYKSSGDEP
                     WAQKMLEDFKNDKSGNITITSSKGVQCLLTYHPITRGLNDWHFLLIVPEDAVLGELNK
                     LNSFTITMTFIITCIIGIITLILYIIRRKYVNQIENIAYLDSITNGINSTKFSMLVKP
                     LISESPDSTYMMIAMNIKDFKLINDCFGSEKGNMTLKHLYNILYKNIDENEEFVCRHD
                     ADLFYLLIKNRPVLEALELLYKIEADTNYFNKNRENPYFLRLSVGIYTIENHNEDLIT
                     IQDHANTARKSFNKTHQSDFSFYSDIERKRLISEKEISNLMEKALENKEFFMCLQPKI
                     DIKSGKISGAESLVRWKNSEKGIIYPSDFIPLFEKSGFICKLDLYILEETCKLISKWI
                     KEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKYNVPTCLIDLELTESIFLENPEAID
                     IIEDIHSNGFKCSIDDFGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSI
                     IELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVFSKPLLISDFENFAYENNKIK
                     NIHY"
     gene            62766..64796
                     /locus_tag="PC465_000200"
     CDS             62766..64796
                     /locus_tag="PC465_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2647536.1"
                     /translation="MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNI
                     VLRSLNKSVIQKMNKGVLIIPDDFQVVCINNNEYVFSLTERVSIMKIISMFKIDNLNL
                     EKLSKEFQVSRSSIKNDLNVLSSELERNQITITYDKSFKISGEEDIIYKQRLNILKSY
                     SYLFGKEKSDLSVFEKYLVNVIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYV
                     SNIFLFTWYIHSDEKHPLESASLSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFF
                     TNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKGLLNHIAPLIERIKQ
                     NIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLSQIKNENETILLAIHFLGSIHRNER
                     NNYKNILLVCGFGYGVIAMLKDSLVNDYQINIVESIPSYKLQDYKEWESIDFIITTSK
                     IVIDLPKTIIEINPFLQEEDYLKFEEKGIKRKNVLTNYMSIKKRLDFLEEDAQKRVLS
                     IICQELGYSDERILFRQLNLSDLIGIDTIRIIDGDMKWEDAVKFSSNILANCDFVSAQ
                     YAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVKIIF
                     CLASRDKKEQIPAIINLTKMVYKTNFIAMLESAKTKEEAEVLIHKYEKEVTV"
     gene            64793..65245
                     /locus_tag="PC465_000201"
     CDS             64793..65245
                     /locus_tag="PC465_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2647537.1"
                     /translation="MNKLVNVKCSFKIHVNSKEEAIISLVDVVSKEGYLIDKNQFLKD
                     VLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKLDTPIEWTEEGEKVDLIFLISVT
                     KDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEEED"
     gene            65247..66302
                     /locus_tag="PC465_000202"
     CDS             65247..66302
                     /locus_tag="PC465_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HDF2647538.1"
                     /translation="MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPET
                     GWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIA
                     GFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLVGTLITGGIIVFLIGEPIASFMTWMTN
                     WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIP
                     PIGLGLATLLFPKKFSKEERDSGKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSI
                     VGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVAVLMKLVKKDVKEDE
                     EIEEDLDESIELIFEEL"
     gene            66369..66677
                     /locus_tag="PC465_000203"
     CDS             66369..66677
                     /locus_tag="PC465_000203"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HDF2647539.1"
                     /translation="MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGI
                     DNELSLKDIDEATCVILTNDVEIRNMERFKGKKVVRMSVSEIIKKSDALIKKIKDTFQ
                     "
     gene            66781..68046
                     /locus_tag="PC465_000204"
     CDS             66781..68046
                     /locus_tag="PC465_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II D-tagatose-bisphosphate aldolase,
                     non-catalytic subunit"
                     /protein_id="HDF2647540.1"
                     /translation="MKKLPIKTVVQRLLNLQEEGKSATLLGIGPMSPNLLQASFELAK
                     DDDFPLMFIASRNQVDADELGGGYVNGWNQETFTKDIKKVADKVGFDGLYYLCRDHGG
                     PWQRDKERNDHLPVDEAMELGKKSYLADIEAGFDLLMIDPTKDPFEIGKVIPLDVVLE
                     RTVELIEYCENERKRLNLPDIGYEVGTEETNGGLTSTETYETFITRLKVELDNRGLPM
                     PTFIVGQTGTLTRKTEQVGTFNFRNAYDLAQMAKKYGVGLKEHNGDYLDDVTLLEHIP
                     SQIIATNVAPQYGTEETRAYLKLAEVECKLEKEGLVEKTSNIRHVLLVNAIECGRWRK
                     WVVGEQKNLTTEEIFKDEVLSNEILDIAGHYTFNNDDVKKEIEVLYDNLSKNNIDGQR
                     FVVDHIKRPLRDYAECYNLKGVTTRILNK"
     gene            68134..68850
                     /locus_tag="PC465_000205"
     CDS             68134..68850
                     /locus_tag="PC465_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDF2647541.1"
                     /translation="MINLIFDVDDTLYNQLTPFYTAYNKVFSSIKDISIEDLYMSSRK
                     YSDEVFHMTENGEMPIKEMHIYRIMKAFEELGNSITEKDAQSFQDEYIYQQSQITLIP
                     EVERILNFSKERNINLGIITNGPSNHQRMKLKQLNIENWVDKSNIFISSEVGFSKPDT
                     NIFRVAENVMNLDRENTYYVGDSYRNDVLGAKKAGWKSIWLNHRGHEVEELFYKPDFV
                     ILEHKDLISLFIKICSYKNM"
     gene            complement(69045..69338)
                     /locus_tag="PC465_000206"
     CDS             complement(69045..69338)
                     /locus_tag="PC465_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HDF2647542.1"
                     /translation="MRNMIENLIKNNTYIDDKVIMLSMLSSAKASANMYLNSALTSST
                     PELRAIYSASLTQMVEGHTALTELSINKGWVKPYDKPIQQLTCSYKESQNVID"
     gene            complement(69344..69559)
                     /locus_tag="PC465_000207"
     CDS             complement(69344..69559)
                     /locus_tag="PC465_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647543.1"
                     /translation="MRILSETEKISLAAIIKMESDGLLMQRAINMLISDEDLKRQSES
                     SILATEGRIKAIQQFIVENEILISEEV"
     gene            complement(69971..70483)
                     /locus_tag="PC465_000208"
     CDS             complement(69971..70483)
                     /locus_tag="PC465_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2647544.1"
                     /translation="MLEVIKNRRSIRTYIDKNIEEDKITEILKSAMQAPSSKNAQPWE
                     FIIVDDKELLKQLSKSQHRAKHIEFAPLCIVVLGNRDKFLKPGKWIQDLGACTQNLLL
                     EVTNQGLAACWAGVFPKNKVVNKVRQTLDLPLKLVPYALISIGYSEEKNEFIDRFDEN
                     KIHRNVYKNR"
     gene            70933..71409
                     /gene="purE"
                     /locus_tag="PC465_000209"
     CDS             70933..71409
                     /gene="purE"
                     /locus_tag="PC465_000209"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HDF2647545.1"
                     /translation="MKVAVVMGSKSDYPKLEEGIKLLEKYGIEVVARALSAHRTPEQL
                     SIFLKEIEDDTDVIIAAAGKAAHLPGVIASQTLIPVIGLPIKSSTMDGLDSLLSIVQM
                     PKGIPVATVTIDLGLNAALLALQIMTLKYPKLKEDLKSYREEMAQKVLEDDKNLRG"
     gene            71415..72113
                     /locus_tag="PC465_000210"
     CDS             71415..72113
                     /locus_tag="PC465_000210"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDF2647546.1"
                     /translation="MLLYEGKAKQVYSTDNENEYVVYYKDDATAFNGEKKAEISSKGI
                     LNNKISTIIFEMLKENNINTHFIKSLSDREMLVKKVEILPLEVIVRNIAAGSICKRVG
                     LEEGVVFDEPIFEISYKNDAYGDPMLNDDYAVAMKLATREELKFLREETLKINELLKA
                     FFLKLNLKLVDFKIEFGKDSEGNIILADEVSPDTCRLWDVNTNEKLDKDRFRKDLGDL
                     VEGYTEVLSRMNNK"
     gene            72125..73492
                     /gene="purF"
                     /locus_tag="PC465_000211"
     CDS             72125..73492
                     /gene="purF"
                     /locus_tag="PC465_000211"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HDF2647547.1"
                     /translation="MCGVLGIYSNKDVTKELYYSLYSMQHRGQESCGLALLDDGEIKY
                     KKDMGLVGDVFKENELSKLKGNIGIGHVRYSTAGGSHVSNCQPLVGSCRKRQLAIAHN
                     GNLVNANYLKDMLEEDGYMFQTNSDTEVILYILARYYKGDIVESLKVTMDYIKGAYAL
                     VIMSQEELVAVRDPHGFRPLVLGKKGDEYIFASENCAIDILGGEVIRDVEPGEIIVVK
                     DGELKSYFYSENYKPVKKSCIFEHIYFARNDATIDNVNAYEFRIKCGERLAQNETVKA
                     DMVVPVPDSGWPGAIGYANASGLKISEGLVKNRYVGRTFIKPTQEEREIAVKIKLNPL
                     STIIKGKSIILVDDSIVRGTTSKQLVKSLREAGAKEIHLRITSPPVAYSCYYGIDTPN
                     RSKLIASSNNVEEMREYIGCDSLKFLDIEGMLDATEHKSTFCKACFDGEYPVKKIDKE
                     ELLSC"
     gene            73486..74562
                     /locus_tag="PC465_000212"
     CDS             73486..74562
                     /locus_tag="PC465_000212"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HDF2647548.1"
                     /translation="MLTYKESGVDIDEGNRAVDLIKGKIKGTYDGNVVGDLGNFSGLY
                     SLKDFVGMKEPVLLASTDGVGTKLKIAQMMDKHDTVGIDLVAMCVNDLICQGAKPLFF
                     LDYIALGKLVPEHIEKIVGGIADGCKMSGCALIGGETAEMPGMYGEDDYDLAGFSVGI
                     ADKEKIVSGNNVKSGDVLVGISSSGVHSNGFSFIRKIFLETYNYKMEQYVEELGMTVG
                     EALLTPTKIYVKLALDVLAKHDIKAIAHITGGGLIENITRVIPKGLGLDINKKSWEKP
                     PIFKMIEGFNAVDERELHKSFNMGIGLVLIVDKENADDVVNFINNRENDNADYVDKKY
                     SELLEDKAYIIGEVVDSHEGVELC"
     gene            74556..75149
                     /locus_tag="PC465_000213"
     CDS             74556..75149
                     /locus_tag="PC465_000213"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HDF2647549.1"
                     /translation="MLNIGVLISGGGTNLQAVIDGTESGEIKGQVKVVISSKQGAYGL
                     ERAKNHNIKAICETDEDKIIEILKENKIDLVVLAGYLKIISPKLVNEFRNKMINIHPS
                     LIPSFCGAGFYGEKVHQGVIDYGAKVTGATVHFVDEGADTGPIIMQDVVKVNQDDDAK
                     TLAKRVLEVEHRILKESISLFCENKIKLQGRRVFINE"
     gene            75142..76674
                     /gene="purH"
                     /locus_tag="PC465_000214"
     CDS             75142..76674
                     /gene="purH"
                     /locus_tag="PC465_000214"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HDF2647550.1"
                     /translation="MSKRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGV
                     NVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKESHVETVNEHKIHSIDLVAVNL
                     YDFEGTLKAGKSHDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTDT
                     MTLEDRKKLSYKAFSTTGRYDALISSYFAGEVGDTYPDILNLTFQKEQTLRYGENPHQ
                     NGFLYSQSNAKNPILNYEQLGGKELSFNNLNDLHGCLEVMREFKDSEEVVSVAIKHAN
                     SCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEKLNEIFLEIVVAYDFE
                     PEALEILKQKKNLRILKLAKIENSLQPYEMKYLDGKLLIQDRNNILAEKSENVTKEKP
                     TDAQLKDMEFGMRVVKNMKSNAIAIVKNGQTLALGCGQTSRIWALKNALENNKDKDFT
                     GAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHF
                     KH"
     gene            76685..77935
                     /gene="purD"
                     /locus_tag="PC465_000215"
     CDS             76685..77935
                     /gene="purD"
                     /locus_tag="PC465_000215"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HDF2647551.1"
                     /translation="MKILVVGGGGREHAICWKLSKEKNVEKIYCAPGNAGIANVAECV
                     NIGDTNIEELLKFAKENEIGLTIVGPEVPLVMGIVDEFEKEGLRVFGPNKKCAQLEGS
                     KAFSKEFMIKHNIPTAKYKEYTNLEEAISEIDSFGYPVVIKADGLAAGKGVVIPENRE
                     DAIATLKEMMSDKKFGAAGDKIVIEEFLKGIETSILAFVDNDTIVPMASAKDHKKVNN
                     YEQGPNTGGMGTFSPSEIYTEELANKVKETVLEKTLEGFKKDGLNFKGILFVGLMITE
                     DGEKVLEYNVRFGDPETQSVLFRLETDLHEIMEAILDNKLKDIEINYSDDEAVCVMLT
                     SGGYPDSYEKGKIITGLENLDDDIVVFHSGTKMFDGNLVTNGGRVIGITAKSTTVKDA
                     AEKVYENIKKINFEGMHYRTDIGR"
     gene            77960..81766
                     /locus_tag="PC465_000216"
     CDS             77960..81766
                     /locus_tag="PC465_000216"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HDF2647552.1"
                     /translation="MLNTENKDSMVRRVLVEKREGFDLEAKALKKDLVESLHIDNIEN
                     LRILNRYDVEGISEEVYENAAKTIFSEPNLDVVYYEEIPKLNDERVFAIEFLPGQYDQ
                     RGDWAAQCVQIVNQGIRPAINTAKVYILSGKITDEEFSKIKDYCINPVDSREASLEKP
                     ETLKMETEIPTTVEVLDGFIDLDENGLKTFVSEKGLAMTLGDLQHVQKYFKDTEKRNP
                     TITEIKVLDTYWSDHCRHTTFMTEIENVKIEDGKFNDIVKEAYQMYLNSRDNVYVNRH
                     KDICLMDIATVAVKELKKNGKLNDLDESEEINACSINVDVEVDGKMEKYLVMFKNETH
                     NHPTEIEPFGGAATCLGGAIRDPLSGRSYVYQAMRVTGSADPRTTLEDTLPGKLMQRK
                     ITTEAAHGYSSYGNQIGLTTGQVAEVYDENFVAKRMEIGAVIAAAPKENVVRERPEAG
                     DVIVLLGGKTGRDGCGGATGSSKEHSEESILTCSAEVQKGDAPNERKIQRFFRNKEVA
                     QMIKRCNDFGAGGVCVAIGEIADSLDINLDLVPKKYDGLDGTELAISESQERMAVAIK
                     KENKDKFIQLAVEENLEATHVATVTDTGYLRMFWNGKAIVDINREFLDTNGVKQTTDV
                     HVTKVDEENTFFSSNEIVKDVKCASMKDKFTKVLSDLNVCSQKGLVEMFDNTIGGNTV
                     LMPFGGKYQATPTQGMVAKIPVLGGETNTSTIMTYGYNPKVGKWSPFHGALYAVVESV
                     CKLVAIGGNYSTTRLTFQEYFEKLGNNPEKWGKPFSALLGAFYAQSKFEIPAIGGKDS
                     MSGTFKDIEVPPTLVSFAVDTVDAKKVVSPEFKKADSKVVMLCVNKAENDVVDFEELK
                     RNLDKVRELIHGNKVLSTYALGFAGVGEAISKMAFGNKIGFKFSEEAEKAFTDDKLFE
                     ASYGNIVLELANDDLSMLEGYNYVVLGSTVKEASIFIKGEELALDELYKAHCSTLEPI
                     FPTKTEEVKSKIETISYISQGEAKKSSLSIATPRVFIPAFPGTNCEYDSARAFERAGA
                     NASIRVFKNLTYKDIEDSIDTIVNEIKSSQIIMLPGGFSAGDEPDGSGKFIATVFRNP
                     RVQEAINEFLTQKDGLMLGICNGFQVLIKLGLVPYGEIRVPSESAPTLTYNNIGRHQA
                     KIARTRISSNKSPWLAQTNVGDIHNIAISHGEGKFVASEDVMRELIANGQVATQYVDF
                     NNEATYDIEFNPNGSFYAVEGITSADGRVFGKMGHSERIGEEVYKNIIGEKDQKIFES
                     GVKYFR"
     gene            81972..82844
                     /gene="rfbD"
                     /locus_tag="PC465_000217"
     CDS             81972..82844
                     /gene="rfbD"
                     /locus_tag="PC465_000217"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HDF2647553.1"
                     /translation="MKILITGSNGQLGKELVNQLEAINQSINQPKYVILATTRSDLDI
                     SNQTNVDNFILHNKPDVVVNCAAYTKVDACEDNIEIAYKINALGVRNLAIASEKVNAK
                     LIHISTDYVFNGFSKYPYREDNKTEPNSVYGKSKLMGEKFVEQFSHKYFILRTAWLYG
                     NGNNFVKTMIKLSLENKEVNVVNDQFGTPTSTVDLAKIIIRIMETEHYGVYHATCEGE
                     CSWYDFAKKIFKLKNIDIKVNPIKSNEFKCKAPRPLYSVLDNFMLKLIGLNSFRKWEE
                     SIEEYLERYDINEK"
     gene            82953..83822
                     /gene="rfbA"
                     /locus_tag="PC465_000218"
     CDS             82953..83822
                     /gene="rfbA"
                     /locus_tag="PC465_000218"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HDF2647554.1"
                     /translation="MKGIILAGGSGTRLYPITKCISKQTLPIYDKPMIYYPMSVLMLA
                     GIQDILIISTPRDIKAFEELFGDGSSLGINITYAIQEKANGIAEAFIIGEEFIGNDRV
                     SLVLGDNIFYGYGFSERLENAVKRKGATIFGYHVSNPNSFGVVEFDKDFNVLSIEEKP
                     TVPKSNYAIPGLYFYDNDVVEIAKLVEPSDRGELEITSINSEYLKRGKLKVELLGRGM
                     AWLDTGTHKGLLDASNYVEVVQTRQGLYIACLEEIAYTKGYISREQLMKLAKPLIKTE
                     YGQYLLKLASEDM"
     gene            83871..84428
                     /gene="rfbC"
                     /locus_tag="PC465_000219"
     CDS             83871..84428
                     /gene="rfbC"
                     /locus_tag="PC465_000219"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HDF2647555.1"
                     /translation="MGKINVIKTKIEGLYIVEPNVFYDERGYFMESYNKKDFIEQGLD
                     MCFIQDNESSSRKGVLRGMHFQVKYPQGKLVRVTEGEVFDVAVDLRKDSQTFGKWEGV
                     ILSDKNKKQFYIPEGFAHGFLVLSEKAVFSYKCTNYYYPEFENGFIWNDKQISIEWPL
                     KGIEEIFLSEKDKKQKSFKDICTRR"
     gene            84466..85449
                     /gene="rfbB"
                     /locus_tag="PC465_000220"
     CDS             84466..85449
                     /gene="rfbB"
                     /locus_tag="PC465_000220"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HDF2647556.1"
                     /translation="MKKILITGGAGFIGSNFIHYMLNKYVDYFIVNLDLLTYAGNLET
                     LIEIQDNSNYKFVKGDISNREQVYKLFEEERFDIVVNFAAESHVDRSVENPDLFIKTN
                     IIGTQVLLDASIKYGVKRYHQISTDEVYGDLPIDRKDLFFTEQSSINPSSPYSASKAS
                     ADLLVNSYYRTYGLLTTISRCSNNYGPYHFPEKLIPLMILNALENKQLPVYGNGENVR
                     DWLHVYDHCTAIDLIIHKGNIGEIYNIGGHNERSNLEVVKVILNLLGKSEELISYVND
                     RPGHDLRYAIDATKIENELGWKAKYDFDLGIKETVKWYIENESWWKAVLSV"
     gene            85479..86147
                     /locus_tag="PC465_000221"
     CDS             85479..86147
                     /locus_tag="PC465_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HDF2647557.1"
                     /translation="MNEISSLINILALTQLSGSNTTNQCNCTYNNSSGFDMIMMTLLK
                     ALSQNNQHTSNSYNLLSNSENLFNELDNVVNNTTSRFIDVDTKDKNVKLRIENAVDQA
                     SKKYNVDSNLIKAIIKVESDFNPNTVSSAGAKGLMQLMPENCRDLGVTDPFNIEQNID
                     AGTRHIKEYIDMFGGSIEMGLMAYNGGPGRMKSRGVESISDLYKMPKETQNYIPKVMK
                     YYRG"
     gene            86156..86584
                     /locus_tag="PC465_000222"
     CDS             86156..86584
                     /locus_tag="PC465_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaaR family protein"
                     /protein_id="HDF2647558.1"
                     /translation="MGINIDKLNISPSINMEVKKLKESNKFSDKLNSLKQSSSLEDIK
                     RNLESVKKAGERLVLTQNYGDISIYKNAVKEYLKSVVDNMYSLDKNSSFWEHQYYKNV
                     KIVDSKLEDMTSKLISEEKENIDIVSTVDMIQGLLIDMYR"
     gene            86608..86922
                     /locus_tag="PC465_000223"
     CDS             86608..86922
                     /locus_tag="PC465_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HDF2647559.1"
                     /translation="MNSKKEDIYELNFGQLIEEKSGVIEENQNVFNAKVNVAVSIGNT
                     TETIKNILDLKEGSIIKLSKNVDEKLDIYANDRLFAYGESIITNERLSVRLSKIEDPD
                     VN"
     gene            87074..87349
                     /gene="flgM"
                     /locus_tag="PC465_000224"
     CDS             87074..87349
                     /gene="flgM"
                     /locus_tag="PC465_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HDF2647560.1"
                     /translation="MDIKNVSSNIVVNNYLKNTSGIKKVEEVKKINKTDKIELSKFAK
                     EMASVSNMSDENIRNKKVDEIKNALENGTYKIKPKEIAKKMIEDMRG"
     gene            87354..87770
                     /locus_tag="PC465_000225"
     CDS             87354..87770
                     /locus_tag="PC465_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HDF2647561.1"
                     /translation="MITDLKVIIYEEKNIISKMMELLKEQFDYIVEKDLENLNMLNPK
                     LEDISRELASIEIKRRQLFGDDISMSEVVENSNDGYLKEIYTDLKHILALAKNQQESN
                     DSLIKKELIFTKKMINFIKPADKKTTTYNSYGNIRK"
     gene            87788..89098
                     /gene="flgK"
                     /locus_tag="PC465_000226"
     CDS             87788..89098
                     /gene="flgK"
                     /locus_tag="PC465_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HDF2647562.1"
                     /translation="MAGLFSILNTANSGMNAHQKAIQTISHNISNLDTDGYSRQRTEF
                     ATNSPMYMPSLSNSIARGQLGTGVHVTDVTRARNSFYDYQFRAEAHKYGKTVSKYDYY
                     NTIETILNEPSDYGISAGIDDFFKGWESLSKDINSDSKKSLVVENASNLATLISESYK
                     KLDKLKEDIDSNIDTEIKQINDMLKSLEDLNKSIDIISGSGSTPNDLLDERDRILDNL
                     SFKLDFENSDVKNMLADGKLELNELKNPDGTWKTGISGTLQGLFEMHGKIDTYKSDLK
                     DVSDGLAKQINDVYNTSAGITVTDFFITSNVDGEDIIKINPAIKSNPNELKLTADEAS
                     KIAKLKDEKIDIGVAGGKVSTISDHYKAFAESIGLDSQKVNQDEANQRKIINNIDNSR
                     MSVSGVSLDEEMTELIKIQRSYQASAKVMSTAVQLLDVVINGII"
     gene            89117..90049
                     /gene="flgL"
                     /locus_tag="PC465_000227"
     CDS             89117..90049
                     /gene="flgL"
                     /locus_tag="PC465_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HDF2647563.1"
                     /translation="MRVSTGMMSSSYLNSLQDNLQRLDKVNRQVNTTKEINKLSDNPY
                     KAIKILNSKSEIKTMETYVENCKDTGNWLETTDTALDQLGKLLSDIKKTLVASGDGAY
                     SDDELKTLSNETNEKMKEIANALNATHEGKYIFSGSNTGVPPVECIDNADGSVSLKFN
                     SSLNLNKLNDSLSMDIAQGISVDYNVKLSSLGFDPTKTDPFEELNNISKKLANPDADA
                     IKELTTTCLGDMEQLIENTVNVRSIYGTKANTVEAMKEKNDDSLIQLKDILSQNEEID
                     YGEKLVQLKAAELTYQASLQTGGKLFNVSILDYI"
     gene            90065..90457
                     /locus_tag="PC465_000228"
     CDS             90065..90457
                     /locus_tag="PC465_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HDF2647564.1"
                     /translation="MMKVTLKKGILGFENLKEYELLDIEDNDYLKEFNSTEEEGIGFV
                     VVSPFEIINEYEIVLNQETIEKLEVKSPKDVVLFNIITLGQTFEESTVNMKAPIVINI
                     KTNFGMQIILQDDKYSIRHPLLRGDNGC"
     gene            90451..90663
                     /gene="csrA"
                     /locus_tag="PC465_000229"
     CDS             90451..90663
                     /gene="csrA"
                     /locus_tag="PC465_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HDF2647565.1"
                     /translation="MLVISRKKDEAVLIGESIEVKIVGVDGNNVKLAISAPNNISILR
                     KEIYEKVKSENIKATNKNIKILKSLK"
     gene            90685..91080
                     /gene="fliS"
                     /locus_tag="PC465_000230"
     CDS             90685..91080
                     /gene="fliS"
                     /locus_tag="PC465_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HDF2647566.1"
                     /translation="MYGENPYNSYKQNAVFMASKEQLLLMLVDGAVKYTKIAKTAILD
                     KNTQKAHRELIRVQDIFTELMVTLDQNAGQWAKDMYRVYDFVRYELSRANIRKDIQII
                     DNVLPVIEQIKDTWHEADKKSKEERSRYK"
     gene            91080..91436
                     /gene="fliS"
                     /locus_tag="PC465_000231"
     CDS             91080..91436
                     /gene="fliS"
                     /locus_tag="PC465_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HDF2647567.1"
                     /translation="MELNLAELDKLSKEELLLMLVDGTVKYTNISKEALLNNDYLKAH
                     NELVRVQNIFTELMTTLDQDAGQWAKDMYKVYEFIKSELAIADENKDIKIIDDILPIV
                     KQIRDTWHEVYNQLKI"
     gene            91457..92980
                     /gene="fliD"
                     /locus_tag="PC465_000232"
     CDS             91457..92980
                     /gene="fliD"
                     /locus_tag="PC465_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HDF2647568.1"
                     /translation="MSSISPIRVTGLSGNFDMEGIIEASMIRDKEKVDKAKQEQQIVK
                     WKQEIYRNVIQESKDLYDKYLSVNSPNSIVSEKAYSSTRITSSDESIIVAKGSAGAEK
                     INYQFAVSQMAEPAKFTIKLNSSEPIVQQFPPNASGASSLTIGDVNIPISEQDTTSTI
                     VSKINSLCADNDIKASYSEMTGELIISRKQTGSSSDINLRVIGNDNLAQQIANDNGIT
                     FINDAGGNKVANVYGKNLEADVTDEHGRVTHISKEQNSFNIDNIDYNVNSKGTAKLTS
                     VTDTEEAVKNMQAFVDDYNKLMDKVYGLVTTKKPKDYPPLTDAQKEDMTTEEIEKWEK
                     KAKEGILRNDDELRGFVEDIQSAFFGDGKNIIALRKLGINESENYNKKGQISFNADTF
                     SKALIDDSDKVYKTLAGYSSNYDDKGMFEKLKDIVYEYSGSSTSKLPKKAGIEKTASA
                     SENVYSKQIAEQERNISRLVEKMNDKEKRLYAKYSALESLLNQYSSQMNYFSQAQGN"
     gene            92983..93318
                     /gene="fliT"
                     /locus_tag="PC465_000233"
     CDS             92983..93318
                     /gene="fliT"
                     /locus_tag="PC465_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HDF2647569.1"
                     /translation="MDKLKEKLNLYKDISLQIINLIEKEEYIKISIKLGERQEIINSV
                     SEIDRNDFIQLYNRMELIEIDSRIRDILQGQLLEVKKELHEYKLTKQVNTMYYNLNRE
                     KVNIFNKKV"
     gene            93420..94292
                     /locus_tag="PC465_000234"
     CDS             93420..94292
                     /locus_tag="PC465_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HDF2647570.1"
                     /translation="MRVNTNVSALIANNQMGRNVNAQSKSMEKLSSGVRIKRAADDAA
                     GLAISEKMRAQIKGLDQAGRNVQDGISVVQTAEGALEETGNILQRMRTLSVQSSNETN
                     TAEERQKIADELLQLKDEVERISSSIEFNGKKLLDGSSTEIRLQVGANFGTNVAGTSN
                     NNNEIKVALVNTSSIMSKAGITSSTIASLNADGTSGTNAAKQMVSSLDVALKELNTSR
                     AKLGAQQNRLESTQNNLNNTIENVTAAESRIRDTDVASEMVNLSKMNILVQASQSMLA
                     QANQQPQGVLQLLG"
     gene            94385..96526
                     /locus_tag="PC465_000235"
     CDS             94385..96526
                     /locus_tag="PC465_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2647571.1"
                     /translation="MLLSIVMIVKNEEKILEKTLKSLTTLRNSIESELIIVDTGSTDD
                     TIKISKKYTEKVYFHNWNNDFSSMRNISISYAKGEWLLILDADEILIDSSTIVKFFKD
                     GLDKKFNSASIQLKNLYSYDKKLYGYCSVLRLFKNVDFRYHGKVHEQPIYKNPIFNNV
                     ADFEHYGYLFEDEEIRLNKVKRNEKLLFQELKENDNSPYTNYQLGKNFIILGKYQEAL
                     YYLEKSYELYSKLELAPGYLITSLVKTYLYLGKHKKCERLCLKYIKKDMNNIDIYYYI
                     AQAQVDLGKYENSIDSYKRYIYLLDNYEISTQANSLFSDTDTVGLRDEAIITLIKIYY
                     KLEKYEFVISEYNNIEDVEKKKNVYFSLFMSLYKLNRFEDIKNYYKEVSNSKIEKNSF
                     YRNIEEVINNIKEDEKEYVYKILCDIEGNYGILNQIRINKCVSIDKCKEILNEEKEII
                     YAYIIKIAFEEKIDLLDIFYEMEYVWIEKYLKYLLALERSFNLVLYKYIISRPNTSDM
                     EKIRVYKAISKVVLESISLSDEKYKEIFYLYIMYSYKYIRYIYSNLSDFELIKFVCND
                     LDKFTIEFKHLLDIKNKVNNANEKLEYIHSMRKLLNEYPFYNKIIKILIGELEENIKE
                     SEEFKDLKDSFIISIENMIETGKINDAKLLVDDYSKTFVDDIKILNIKGILYMFENKL
                     DKADFMLKKALSLDVENEDTIYNIEYLKSLR"
     gene            96550..98427
                     /locus_tag="PC465_000236"
     CDS             96550..98427
                     /locus_tag="PC465_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2647572.1"
                     /translation="MNIPIVVNEKSKDIIKDWQYTCTNEDIKFTSIIILTYNQIEYTK
                     LCIESIRKFTPKNKYEIIIIDNNSSDGTVEWLKGQSDIKSVYNNKNLGFPKGCNQGIE
                     LATGENILLLNNDVIVTPNWLYNLNKALWSQDNIGAVGPITNACSYYQQIDVDYKSIE
                     DMFIFAHKINKSNINLWKYRLKLVGFCMLIKKTVLDNVGVLDELFTPGNFEDDDLSFR
                     MIESGYKLLLCQDTFIHHFGSVSFKENRNKYTDIMYINRRKFETKWGFNPEYSGMIRT
                     DLISKIDDSLEANINVLEIGCGIGATLLEIKNIYKNASIYGIEISESAGKLAKYSADV
                     LIANIEKVKLDYKKDFFDYIILGDVLEHLIDPWKIVNELKQYLKKDGYLVSSIPNIMH
                     VSVLRNLVLGNFTYEDSGILDKTHLRFFTLNEITKMFNDSNYIINSITATSMPLSEID
                     NSFIDTICKESCKEMRQQYESYQYIVKASKILDTKRYSSISMINLKYALMRIDNELDV
                     DSNLSYIFDNYNITEPCFVDDIEYLIDTFVINKATLLNRLGVEAFNRGLGDFSINMFM
                     TVLEMDRDDIDSIYNITSVLCELEEFDTAYNLIKNSSEKVQSESDIQEILCFIEGKKY
                     E"
     gene            98420..100534
                     /locus_tag="PC465_000237"
     CDS             98420..100534
                     /locus_tag="PC465_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDF2647573.1"
                     /translation="MNNDKICFITCVNDERLYEECLVYINSLDIPKNFSIETVALRGA
                     DSIASAYNKAMRETDSKYKVYLHQDTFIINKNFIHDILEIFKKNTDVGMIGVAGVKDM
                     PVNGIWWDSDKKAGKVYDSHTGKMDIYEFSNFEECFNEVMAIDGLIMITQYDVFWRED
                     KFDGWHFYDLSQSMEFRQNKYKVIVPKQNKPWCMHDSGVVNINNGYDEYRIKFVKEYI
                     NLDLYRENFYEFDKKKASTILKSNKHVMDCMKEELTEQLRLKNYKDVLGIVSKIAHFS
                     VFNHTGLYSCEECERALLECANNLPEIENTKLFTKKDLKRRKVLHVLSEGYSTGGHTR
                     LVKNWIEIDKDSVHSVVTTWQSDTLPDWLLKAINDSGGEVISLDLISDDYLKRAVALR
                     KIAYDWADIVILYVHMWDTIPVVAFGVDGKIPILHVNHYDSTFWLGTSIADIVIDFSE
                     TSQLITLDKRGIDKSEILPMPLKEKEVFSKSEVRKRYNLEDDVTIILTIASERKYNSV
                     NDINYFKIAKTLIENTDNTIIIVVGVDTENLYWKTLSNVTDNRVICFGTTANIDDFYK
                     ISDIYLESFMVGSHTSKLDAILYDLIPVKFKNEVSPIFTNMWNFIDKFDYKNIKEVID
                     MIRRYNTSEFDRDKIKAKQSEIKHFVIDKHCIEIKNYIDKIYNEVNHHKVKYDLYKND
                     EIEDYQLFVALYGYMVKNKNMS"
     gene            100543..101538
                     /locus_tag="PC465_000238"
     CDS             100543..101538
                     /locus_tag="PC465_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation glycyltransferase
                     FemA/FemB family protein"
                     /protein_id="HDF2647574.1"
                     /translation="MNNIHINKFEKSCEKNWDYFVENKSINGTFLQTRNFLNYHEEGK
                     FTDHSLIICKGEEILAVVPACETYEDGERIFFSHLGSTFGGIIIRSGFNDIRHVNAIT
                     NKLEIYLQEQNFDKVYLKNTSRIFCKEDTSLLEYFLFKNNYMFYDELSMFLELSKYKE
                     DILANFKYSKRRDFKYSLKNNLTFKRLYSDEDIVCFFNLLSNCLDSKGAKVIHSVEEL
                     LEFKNNRLKDIVEFYAVYIDDIMICGSMVFNFQERVYHTQYLASNSTYNKYYPMIFLY
                     YNLIKDALERNFKYLSFGISTLNRGKYLDEGLATFKEGFGSSAICNRTYYKNINK"
     gene            101630..102862
                     /locus_tag="PC465_000239"
     CDS             101630..102862
                     /locus_tag="PC465_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HDF2647575.1"
                     /translation="MKRLMILGSIKYFENIVMSAKREGIYTIVCDNRIDTPAKKICDE
                     AIDVDVFDFDKIKNIAIDKKIDGILTGFTDSLMKPYVYIANELNLPCVISCNQLESVT
                     NKAVMKNYFKNNGIPTTDYCIIESLKDLEKIQGLNFPLVIKPVDGYGSRGVYFVSNIE
                     ELIEKFEYSKEASQDGQVIIEEFYESEEIQGLAWVHNGESHVFYIGDRELVNIHTGRA
                     GKPDRLIYPSKYCFQYEEEIKSIYQNITQAFGIKNGPLYVQMLVGAYGIKVSEVMPRL
                     PGGCDYMAISQITDLDIGSLFANFSVNNEVNFDEIKKYNMHLSKCVYALPIYIRPGTI
                     KKINNIDKIENLDYVTQFLLLVKEGDTIGLYEDERQDCGRVYGVANNVFDANIKKKCI
                     HEMIEILDENNENMIENF"
     gene            102882..103826
                     /locus_tag="PC465_000240"
     CDS             102882..103826
                     /locus_tag="PC465_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase"
                     /protein_id="HDF2647576.1"
                     /translation="MKLITHEQIMSLNISQKQGYEWIKESFLTKKDCQLPPKISMVEE
                     GHVFYNVMPSLNHNHKIGGIKMVTRLPGRNPSLNSEIFLYNMEDAKLKAILDGNYITA
                     FRTAAVAALAIDTFAKKDFNTIAIMGLGVTASAIMNMLSYTLKDKNINIKLLKYKDQA
                     ESFVKKYEKNEQFSFEICDTHEELIVDSDVVISTVTYTDEYLSEFKWFKKGALLLPVH
                     VMGFGNVDYLFDKVYLDDYNHLKHLENIDRYKYSCEFYDVLSKQAKGRENDDERIISY
                     NIGLSIHDILFANKIYELCETLSCEEIELKEPKEKYWI"
     gene            103920..104327
                     /locus_tag="PC465_000241"
     CDS             103920..104327
                     /locus_tag="PC465_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxcM-like domain-containing protein"
                     /protein_id="HDF2647577.1"
                     /translation="MDKYNLIRFVSIGNEYIGNLVALESNKAIPFDIKRVYYIYDVPN
                     NVKRGFHAHKNLEQVLVCLNGSVKIKCYDGVKETIFNLHKNDVGLYIGTGVWHEMFDF
                     DEKTVLISIASEHYNEEDYIRDYKEFLKYLNNM"
     gene            104414..105505
                     /locus_tag="PC465_000242"
     CDS             104414..105505
                     /locus_tag="PC465_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HDF2647578.1"
                     /translation="MLVKFNNLLKQFQTHKEEYEQKIKDVMESGYYILGNEVKHFEEE
                     FANYVGSKYCVGLASGLDALIIAFRALGISEGDEVIVQSNTYIASVMGISINGATPVF
                     VEPNEYYNIDSSKIEEKINSKTKAILVVHLYGQASNMKDIQELCDKYNLYLIEDCAQS
                     HGAKYDGKMTGTFGDIGCFSFYPSKNLGAFGDAGAIVTSNEEIADKVKILRNYGSEKR
                     YYNKFVGYNSRLDEIQAGLLRVKLKYLNEIEIEKSKIVDRYLNEINNPKVILPKIENN
                     CTHVWHLFVLQVEKRDTFMEYLKKNGIESIIHYPIPPHLSEAYAYLGYKKGSFNIAEN
                     YSDKVVSIPLFIGMEDEEVSYIIKIINEY"
     regulatory      105814..105904
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            106314..106631
                     /gene="flgB"
                     /locus_tag="PC465_000243"
     CDS             106314..106631
                     /gene="flgB"
                     /locus_tag="PC465_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HDF2647579.1"
                     /translation="MNTYDIIKMGLDATNLRSQTIANNIANINTEGYKRHYVTFEETL
                     NDAMPKIEEKTDNSKGLRVDGNNVDIEEEKVNQAMTTLQYNALISFANGKIAMTKSII
                     SGR"
     gene            106639..107043
                     /gene="flgC"
                     /locus_tag="PC465_000244"
     CDS             106639..107043
                     /gene="flgC"
                     /locus_tag="PC465_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HDF2647580.1"
                     /translation="MSVFSGMRISASGLTAESLKMDIISSNVANINATRGPNGEAYRR
                     KVVSFEENYDNKLGMLGVKVTSVEDDKSPLKKVYDPSHPDAKPNGYVEYPNVNILVEM
                     TDLITASRAYDSNVDTLNAQKSMISKALEIGK"
     gene            107053..107367
                     /gene="fliE"
                     /locus_tag="PC465_000245"
     CDS             107053..107367
                     /gene="fliE"
                     /locus_tag="PC465_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HDF2647581.1"
                     /translation="MPITQINNLMQGAKLDNLIGETKPLTLNKEEKKNFEDVIIDTID
                     KVNFQQVTADDMKEKFIKGEDVSMHEVMLIGQEAQLSMQYLIEVRNKIHDAYQEMNKV
                     QI"
     gene            107392..108942
                     /gene="fliF"
                     /locus_tag="PC465_000246"
     CDS             107392..108942
                     /gene="fliF"
                     /locus_tag="PC465_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HDF2647582.1"
                     /translation="MIASFKNKIKEQVAKSRTKISSLKKGTKIALGIGVIAICLALVF
                     TAISASKNKYAVLFSELDVQDAADISAELESKKIDTKVKGSTIYVPRTEVDKLRLELA
                     PSLTSGSKGFALMDDSSSIGLTDEEFQIKKQRMIQGEIEKTIKSFPQVEDTRVHITFG
                     ESSVFEKEAVPGSAAVYLMLKPGTTLEKNQIKSVMALISGSVTNIPEKNVQVIDNKMN
                     LLSEGILEDENVNENNQPINSGISVDKNKASEQALNKQLEKSILEILEPIFGKGKVKA
                     TVNADLSFDTAEKTEIKIDPDKVAIKETRSKNSSKSATNNVQGVDANMNNQGNNNGTN
                     TEDSLDESFEYETGKIETHTIVAPGELNRLTASVAIDGKIAKGVQADVEDIVNNAIGM
                     DGARGDTLSVVSMVFDPEGKKEAKQELEEIKKEGFKKNIIKAVIGVVAVVAIGAIGYL
                     IYKKRSEREDMDYEDEDYISKSDSVDRKDNPLLGDDPELTLEEAVKMYAEEKPDQVTE
                     IIKTWLNE"
     gene            108955..110025
                     /gene="fliG"
                     /locus_tag="PC465_000247"
     CDS             108955..110025
                     /gene="fliG"
                     /locus_tag="PC465_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HDF2647583.1"
                     /translation="MSTEITNVNAFDLSDINESDKKEKIEGEGLKKAAVLLMTLGPNV
                     SSDIIKSLPDKQVQKIGLEIANISSIASKERREILKEFVEINRAKDYVIEGGLEYARE
                     LLSNALGNAKANKLLEGISINTSTKPFKHIIKLDVKKILEILRNESAQTIAVLLAHME
                     PENGAEVLSYLDFDLQNEVAMRISSMGSISPEVIKVIESSLEDKLHSMSGDDFKDYGG
                     VSTLVQILINSDRKTEKNILGTIEEQDPDLAAQIKSHIFVFEDIVKLDDISIQKVLKE
                     VTMKDLVYALKGVDDEISDAIYRNQSSRAAEALREEMEMVGVIKVTQVEAAQQKIANI
                     VRKLEREGAITIVRNFGGDFVE"
     gene            110018..110749
                     /locus_tag="PC465_000248"
     CDS             110018..110749
                     /locus_tag="PC465_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HDF2647584.1"
                     /translation="MNNKIIKSKKALYKGVLDLTIIDKVRVGESNVNKENDCRFRDEV
                     IKEAIESAEIKKNEILEEAKMNAQNIEKQAYEKGYSQGQKNGYEDGYKESYNEYTQKA
                     KDEADFIKNQADLILLQANEKMTEYIKEKNKEIVRLAINMASSVLKKHFEDEESMSDL
                     LKQIIQDYEGSSSFIVRCNSFYKDNIEKEFELFKEETSLKSSVFVIADDSIDKGNAII
                     QKENGRIIVGIDCAMEKLKEELLGE"
     gene            110753..112072
                     /gene="fliI"
                     /locus_tag="PC465_000249"
     CDS             110753..112072
                     /gene="fliI"
                     /locus_tag="PC465_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HDF2647585.1"
                     /translation="MYKTDISIDFDKINKKIENLELTISEGRVKKIIGLTVEVEGIKA
                     FVGELCVIYNQVNKPVNCEVVGFKDKEVILMALGELTLIAPGCKVISKGIPLSVMCSD
                     NLLGKVLDGLGNPIDNSDAVLGDRYNLNNEPPDPMKRKKIRNIMETGVRAIDAFTTCG
                     EGQRIGIFAGSGVGKSTTLGMIARNAKADVNVIALIGERGREVLDFIDKDLGEEGMKK
                     SVVVYATSDKAPLVRLKGALTATAIAEYFRDQGKKVILMMDSVTRFAMAQREVGVAIG
                     EPPAQKGYTPSVFAILPKLMERTGTSDKGSITAFYTVLVDGDDFNEPIADTTRGILDG
                     HIVLSRDLANKNHYPSIDVLNSLSRLMNEIASKEDIKIASFARDMLAEYREAEDLINI
                     GAYASGTNKKIDEAIYYHEHIINFLKQGINEKSSFNETISSLRGIFE"
     gene            112104..112550
                     /gene="fliJ"
                     /locus_tag="PC465_000250"
     CDS             112104..112550
                     /gene="fliJ"
                     /locus_tag="PC465_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HDF2647586.1"
                     /translation="MELDKNFKFRLQKVLDLKIKDEEEIKMEFAKIQQKKIDIETNLE
                     NLESNYSKYSIGKNNDSVQNQKITINYLLALNNSIMDLSEKLDKSTNELEKARKQLIS
                     KQIERKSLEKLKEKKYGQYYKEEQLKEQSTNDEFASMSYLRNRQVL"
     gene            112578..113783
                     /locus_tag="PC465_000251"
     CDS             112578..113783
                     /locus_tag="PC465_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HDF2647587.1"
                     /translation="MKIQADSYNIIKDIGNRKNSSKNKNIKNDKFEDNLYKTTDHKKV
                     KDRRETSKQNVSSDRPENSDNECHLDEDKSNHLEDENTYEKDCSNNNEALQQLLNLLK
                     ENYKKDKDINTILNNIKKLSISDELKQELKLNKNILNKIANQNSELNKANINNSNDIE
                     NLDIVKLRELLEDNANKDIEVITKTTENDTKNIDLYSFDSNRMDNLNSNKQKDDSSDI
                     LEKLAGVNGNKSGNFGQVINKNVDMNKIKNDNVNLKQIESNVMDDSIKAIKHMKTNDI
                     QELTIKLRPKELGDMNIQLLKDGESMRAVVTVFNKDVFDSINKNIADLKQHLELTNVN
                     IKDVSVQMHSDNTNTSDTFDKAFEQQNRQNNQENMSKKNTNDKHNNVVIEDDIKENTI
                     DDDRVDLLA"
     gene            113801..114409
                     /locus_tag="PC465_000252"
     CDS             113801..114409
                     /locus_tag="PC465_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlgD"
                     /protein_id="HDF2647588.1"
                     /translation="MYGIATALAGTQGNYRSNNLSQLERNINDIANKQVRSKGNQTVT
                     DNGTPIIGQGDDADKDLFMKILVAQMGNQDPMNPQDPTEYVSQLAQFATLEKMSAMNE
                     KLDVLLALSNSTLINSALSMATSLIGKEVEVSGEEKEDENIVGVVKSTYIKDGEVHLE
                     LEVDGSDKTVGVKYEKLLKIGEVDENSGEENDSSEHESPEEA"
     gene            114436..115419
                     /locus_tag="PC465_000253"
     CDS             114436..115419
                     /locus_tag="PC465_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein"
                     /protein_id="HDF2647589.1"
                     /translation="MIKAMYSGVSGMKANQTKLDVIGNNVANAGTTSFKKSSARITDS
                     FYQTVLYASAPTAALGGTNLGQVGVGSKISSINKDMVQGNVQPTNRPSDLMIDGDGYL
                     PVVRQGTVMYTRDGSFNLDTGFKAADGALKNIKGGRLVNGDGYMLQGMIYDGEYKADT
                     GEFVKKGDAKGKEPIVIPLQSISPKDGTVQNVLEYNISKDGTVEFLLSDGQRTQFVYD
                     IPDGAKVGDTPAGIDKLKGTIQKVQTYAFQNPAGLDAEGGNLFKPSANSGDPQIAGAT
                     GTIIQGAIEASNVDIAEEFTEMIIASRSFQANSKIISTSDEILQEIINLKR"
     gene            115432..115635
                     /locus_tag="PC465_000254"
     CDS             115432..115635
                     /locus_tag="PC465_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar FlbD family protein"
                     /protein_id="HDF2647590.1"
                     /translation="MIRVTDLNGRKYILNSDLIVRIDSVPESRILLTTGEKNLVKESV
                     DEIVDKVIKYKRKINVGYIRSEK"
     gene            115635..116453
                     /locus_tag="PC465_000255"
     CDS             115635..116453
                     /locus_tag="PC465_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HDF2647591.1"
                     /translation="MKKTDSLTFIGLIVSTVLVLVGAAKGSSSGLKNFFDVSSILITV
                     LGSFGALMITFTIDDIKLIKNALQYSFKTMSVSKLDLLEQFKTLSKKARKEGLLSIES
                     DVMGIEDPFMKKGLELCIDGLEINEIRSILELEIDSVEDTNNRYSKLFKTWGTFAPAF
                     GMLGTLIGLIQMLADLTSPDLIASGMGKALITTFYGSLLANIALNPIAYNIDEKTEKE
                     IYVKEMMLEGIISIQSGESSIVVEERLATYLSNNEKLEIMKSNKNTERAMSNGA"
     gene            116443..117138
                     /locus_tag="PC465_000256"
     CDS             116443..117138
                     /locus_tag="PC465_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDF2647592.1"
                     /translation="MARKKNKKKDEINPDAWLATYADTITLILTFFVLLYATSVVDME
                     KFKNIADALKGQFSGTSIFSTGSSTSEKSPIDSVLVDKNDKSNLEQDLKDKVNNSNLQ
                     NSVTVKDDSRGILLELDDSILFDSGISELKVDSKATLNKVYDMIKMMKNKIVIEGHTD
                     NVPVKSSTHESNWDLSSSRAVSVVRYFVEEKGMDPRLFSATGCGEYQPLVSNETAKGR
                     AENRRVNILITID"
     gene            117150..117593
                     /locus_tag="PC465_000257"
     CDS             117150..117593
                     /locus_tag="PC465_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated FliL family
                     protein"
                     /protein_id="HDF2647593.1"
                     /translation="MFKNKKIIIIILILIIFSAGAGFFILGEGGNKQVDKIAGLFIPT
                     GKGKDEVKTENLDLEEMVLKLADEGVRYLKVSITVSYDSSYKDIEKNTPLIRDNIINC
                     FMAKRADDFTADNLKNIKEEIKNTLNIQLGENVIQNIYFTNIVVQ"
     gene            117608..117982
                     /locus_tag="PC465_000258"
     CDS             117608..117982
                     /locus_tag="PC465_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliZ"
                     /protein_id="HDF2647594.1"
                     /translation="MILYLLKILICIPIILILIVLSLKISQGTLLKKYNDKYVKILDI
                     VNISKNNSIIILKIGEEGCIMASSSSSMSKIKDLTKEEVLKIENDIKERNFKIQDFKM
                     ERIKKKYDFSRYIGKFTKKEDK"
     gene            117983..118648
                     /gene="fliP"
                     /locus_tag="PC465_000259"
     CDS             117983..118648
                     /gene="fliP"
                     /locus_tag="PC465_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425215.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HDF2647595.1"
                     /translation="MELLSKLPLADVPYTSSMQLFLFLTALMFLPFVMFMMTSFVRIV
                     ISLSFLKSALGAQQAIPSQILVGLAIVLTIFIMRPVLNEINEKALQPYMKEEVTMEEA
                     MKEAEGPIKEFLLTQTRQTDLDLFVEQAGLKEKKLTRENIPLSVVVPAFAISELKTAF
                     QIGFLIYIPFLIIDLVVASVLMSMGMFMLPPVMISLPFKLLLFVMVDGWNLIVKTLIL
                     GFG"
     gene            118661..118930
                     /gene="fliQ"
                     /locus_tag="PC465_000260"
     CDS             118661..118930
                     /gene="fliQ"
                     /locus_tag="PC465_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HDF2647596.1"
                     /translation="MSEFMIMSVLKNGMFTGAMIAAPVLIVSLVVGLLISVFQATTQI
                     QEQTLTFVPKLIAILLVVAIGGSWMLHTLISFTSEIFNMISLITK"
     gene            118942..120756
                     /locus_tag="PC465_000261"
     CDS             118942..120756
                     /locus_tag="PC465_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused FliR family export protein/FlhB family
                     type III secretion system protein"
                     /protein_id="HDF2647597.1"
                     /translation="MIFVFIRIVAFFGTLRILFPAGTPALFKSLFAIIISILISSTMQ
                     IEYATNIDNIVLFTLYSVNETITGIMLGYITNLCFYSIRMAGSMMDQQMGLSMINMFD
                     PNSMTQTTLIDNLMNWTALMIFFNMDGHHVLIRGIRYSFELIPIGKPFVDNNIDYIIN
                     IFVQCFLTGFKIAIPIVLCLLMADFILGLISRSVPQLNVMIVGMPLKILVGIALFIIS
                     IPLIVNQISHLLSQIPKMYEGTFALAPMFFMGSADKTEEATPKKKGEQRKKGNIAKSR
                     ELPVAMTLLAFTLLVPTLFSYVVDTLKSSLNYFLSLDFYMNINYSNLEKLVIAGLMDF
                     FKIFLPIAIPFLVLGIIANLFQVGILFTGETLKPNLSKLNPISGFKNMFSMRSLSTLI
                     KDTAIISILAYIGYTFFQDNYLDILKLGNIYLPTLMYTVKDLVYSILSKICVAMIAIA
                     VADYVYQRYSHKKQLRMTKQEVKDEYKNSEGDPEVKAKIKQKQRQISSQRTMQAVPSA
                     TVIVTNPTHLSIAVRYEKGKDQAPVVVAKGADYLAFKIREIAKGNDIPIIENKPIARL
                     LYKQVEIDQEIPEDMYQAFAEILVAVYKIKNRYKVPKR"
     gene            120765..122840
                     /gene="flhA"
                     /locus_tag="PC465_000262"
     CDS             120765..122840
                     /gene="flhA"
                     /locus_tag="PC465_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HDF2647598.1"
                     /translation="MNKFNLKENMDVIVAFGVVGIVLMMIVPLPTFILDILLAINISL
                     SVLILLMTLFTTNVLDLSIFPTVLLVTTLFRLGLNLSSTRLILTQGYAGEVIEAFGSF
                     VVGGNYVVGIIIFLIILIVQFVVITNGSGRVSEVTARFTLDAMPGKQMSIDADLNAGV
                     IDDKTARKRRKELQQEADFYGSMDGANKFVKGDAIAGLIVTAINIIGGIVIGAVMLNM
                     TLMGAAQTYVRLTIGDGLVSQIPALLISTSAGIIVTRASTDENFGGLVGKQLTAIPKA
                     VMMTGCVLIVLGMMPGLPKPAFFSLGIGAIAAGYFLGREKKDTLEDLEFEKPDMVNPD
                     KNEVEDVTNLINVESIEVEIGYGLISLADESAGGDLLQRIASIRRQCAIDMGIVVQPI
                     RIRDNLQLNPNQYNIKIKGNVVGGYEIMPNMVLCMDPMNQGFSIFGIKTIEPTFGIEA
                     LWIESDKVEDAELKGYTVVDSSTILITHLLDIIKSNAHELLGRQEVKTIIDAARENYS
                     AVVDELIPDLMTLGEIQKVLKNLLREKVNIKDRVTILETLADQSRNTKDIELLTEYVR
                     IALARSICNNLVDEDKAIVVATLSPETEELVSNNLQRSVNGTYPAVDPENTNKIFESI
                     QEVMNNVYFNHNIPVIVVSPKIRAPFRKLVEIVYPNLTVLSLNEIPNDIKIKAEGVVS
                     IYDDEKVYS"
     gene            122815..123831
                     /gene="flhF"
                     /locus_tag="PC465_000263"
     CDS             122815..123831
                     /gene="flhF"
                     /locus_tag="PC465_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhF"
                     /protein_id="HDF2647599.1"
                     /translation="MMTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIRGIFS
                     KKDIELTIGWEKKDNLEQKDLKREIEQLKSIINNMGFDNKNDNDIDKICKNLLNLDLN
                     QEIVEFIKADLQEMKFNGIDTSKNLVESLKKKIKIENQAINGKIALVGPPGVGKTTTI
                     AKLAAKLVFEENKKVGVITIDTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDAM
                     KDCDVVLIDTTGRGYKNSMQILEIKNLIDKAETDNIHLVLNCTTRESDTKAIIDSYRN
                     VNFKSLIITKLDETITYGSIFNIMNYAQKPISYITTGQNVPDDIIKPNEDKIIRLLLG
                     VESI"
     gene            123828..124706
                     /locus_tag="PC465_000264"
     CDS             123828..124706
                     /locus_tag="PC465_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MinD/ParA family protein"
                     /protein_id="HDF2647600.1"
                     /translation="MIDQAQILRKMAMEKRGSDEIIVENENMPKIITIASGKGGVGKS
                     NLATNLSICLTKLDKKVLILDADIGMSNIDIIMGVNVKGTIIDVINGEKNIEDIISQT
                     KYGVNVISGGSALNHIEDFTEAQRNKFIHSIEQIHNVDFIIIDTGAGMSKSLLSFIYC
                     STEFFLITTPEPTSLTDAYSLLKAISNFGIKKSANIIINRVIDLEEAKSTYKRIKMVV
                     DKFLNLNLELYGYIIDDKKVSLCVKKQIPFILEYPTSIASKCIIAIAKRMVSQSREDI
                     VDNKSFLRKMFSIFKS"
     gene            124720..125421
                     /locus_tag="PC465_000265"
     CDS             124720..125421
                     /locus_tag="PC465_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliA/WhiG family RNA polymerase sigma factor"
                     /protein_id="HDF2647601.1"
                     /translation="MNREELIKENMPLVKSIARKFFIPGKGFEYQDLVNSGVIGLIDA
                     INKFDAEKGAKFSSYSYIKIKSAILDEIRNQSPISKHNLTKVNKYNRVVEKLQSKLLR
                     EPTSYEIAKELKVSEKELHDIESNIDMLNIVSLNYVIFEDTNETVQDVISDREEEAPE
                     NIIEEEEKLEILSKAISNLNEREKLILSLYYYEDLNLKEIGKVLGVSESRVSQLHRKS
                     IRNLRNKIKELKYSI"
     gene            125437..125859
                     /locus_tag="PC465_000266"
     CDS             125437..125859
                     /locus_tag="PC465_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HDF2647602.1"
                     /translation="MIQIILIVVSILIIVTIVINLHKESKNKDNRYFDKIFEQEYEAN
                     DRLIIAEKRRFFLDKVLAEIRSNNHIKVYENYNLIKANEERKENIFIESKKEVRQENE
                     LSLKVKHLISSGYDDVEICKMLDIGKGELSLIRSCYKI"
     gene            125844..126029
                     /locus_tag="PC465_000267"
     CDS             125844..126029
                     /locus_tag="PC465_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HDF2647603.1"
                     /translation="MLQNIRILLCDKKVFLGIGIGILISTLCIMLFSNNDMSKAEIEK
                     KARALGMKYTSEMKVLE"
     gene            126070..126843
                     /gene="flgG"
                     /locus_tag="PC465_000268"
     CDS             126070..126843
                     /gene="flgG"
                     /locus_tag="PC465_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HDF2647604.1"
                     /translation="MIRGLYTAVSAMITNQQKQNVVVNNLANMDTNGYKSKQLLTKSF
                     DELKLEGYNNYANGTKQKQIIGDISPGISMDETITNFNQGPIKTTDNKMDVAIQGKGF
                     FLVSDAAGNQFYTRNGNFRTDNQGDLITSEGYYVLGTNTATGAVGHINVGNQKFEVAK
                     DNTISLDGNAMYKFNIVDFNNYNNLKKEGDNLYSGGGAMKVNNALTIQSAIESSNVDM
                     VSEINNMMTISREYEANQKIIQAMDSKLAKIASEIGSVR"
     gene            126864..127625
                     /gene="flgG"
                     /locus_tag="PC465_000269"
     CDS             126864..127625
                     /gene="flgG"
                     /locus_tag="PC465_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HDF2647605.1"
                     /translation="MYTMFYTSKTALSANQSKLDIISNNIANSDSTGYKKINMEYSDL
                     VDEVLNRPSYPTNGKDISTGTGAKATAPMRNYEQGALAPTDSKSNLAIDGEGFFRVIR
                     KDGTYAYTRNGGFNVDALGKIVDDNGNILDVQFDAGYNYNNTNIDSTNLTVSRNGELF
                     VDNKKIGKINLYQPIGTQNFISEGDSLFVATDAAQIKQVEKVDIVQGYRERSNVSLQE
                     EFVDLIATQRAFQMNSKGIKTADEMWQIANNLRAK"
     gene            127648..128529
                     /locus_tag="PC465_000270"
     CDS             127648..128529
                     /locus_tag="PC465_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HDF2647606.1"
                     /translation="MNDMKEYDFGKPQSYSRENLTCLNFLLAEFCKKYKNYIIYELKC
                     NSSMVVDSIDQVNYQTFLDRVTSSCVVVQNAMEPVMKNFSFRIDRSVADMWIDITSGG
                     TGVVKDNDRELTELDKKVLLHLMDDLVRNMHLFEGFENIQVLDTHTHINLPQLCSPTA
                     PVCVVDLKVLNDNEYIGSVSLCFPYNGLEALLESISVIEFFDNDIGDDSEEFTKKIYN
                     SVSNIELSVIAEIGKVSINVEDLLKLEVGDVIVTNKKINDYIDIFVENSKSYTATPGF
                     ISSKKGVKINDAVGKEV"
     gene            128532..128906
                     /locus_tag="PC465_000271"
     CDS             128532..128906
                     /locus_tag="PC465_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HDF2647607.1"
                     /translation="MDNSNLISDEEAKMLLNDKVESEVDGDDELALDVSEVNRNNIQR
                     ILDLKLELSVVIGRTKMTLRDILNLHKGSLIELDTLADQDVEILIDNKVLAYGKVVVV
                     DLNFGVKITSIVSEEDMVKSLV"
     gene            128938..130341
                     /locus_tag="PC465_000272"
     CDS             128938..130341
                     /locus_tag="PC465_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2647608.1"
                     /translation="MVLILNLNDIKKDILKLNKKDSCSLYNESINNINNNCISSGLKF
                     LKQARDLNPDDVDILNLTGLVNLLKCNFDEAVESFYKSSLCEKTALCEKYINMLTSEE
                     FLIFFERYNQLIRLINRGMYKEAIQGFKLITEQYCDLIEPYELLALLYDKEEEYIKFD
                     ECLEVLKIIDKENYLLNQENNTLDMYNSANIQTKSNIKVDDYKNEFLHKSSSNHKIND
                     YNDVTKEKSSSKNQKSSDSNKKKSIKKNKYLYIAIILGILLVGQSIYSSYKMNNLTDK
                     ISKNNETKNEESIDSNLTKKENNIEENEDMSKASNINKSNKNINKEDDVKSKKNTVEN
                     EDDKDSDLFTEDELMSKANTLKSEKKTKSSIQLYKKVADIGENKGNTSEATYQVAILS
                     EKLKDYKTAEEYYKMYVENYSEKDAYFDESYYNLGMMYYNNGDLKNSKLTLKKLVNKV
                     PNSMYNNSKVKEILKEE"
     gene            130457..132394
                     /gene="htpG"
                     /locus_tag="PC465_000273"
     CDS             130457..132394
                     /gene="htpG"
                     /locus_tag="PC465_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HDF2647609.1"
                     /translation="MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSK
                     HKRLVSLGEISENKSSDYKITVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAE
                     DFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
                     EISESDTRNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLERE
                     AKEAEEKAKKQKEDGKEEIVDAKVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVF
                     DEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFL
                     LLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWD
                     DIQIFIKYGCLKDESFYEKVKECILFKTIDDEYITLQDYLEKCKDKHENKVFYVSDKE
                     QQSQYIKLFKEYDLSAVVLNSSIDTHFISFMEYKENGVKFNRIDADLSDVLKDKNENK
                     DSEENKEEIAKIEGLFKEAVGERVKHYSVEGLKNEDTPAMVLVSEQSIRMAEMQSRFA
                     GMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKITLICNQIADLALLSNKELK
                     PDELDSFVQRSNKLMSLFIEL"
     gene            132782..133912
                     /locus_tag="PC465_000274"
     CDS             132782..133912
                     /locus_tag="PC465_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF2647610.1"
                     /translation="MNFNYNLPVNILFGRGRINDVGKEVSKYGKKVLIVTGKNSTKKT
                     GLLDKTIDLLKDSKIEYEVFDRVEQNPLITTIYSGVEIIKSTGCDCVLGLGGGSIMDA
                     AKSIAFSYKNSGDLNDYIFGIRQGEEALPIILVPTTSGTGSEGNCFAVLTNSETKDKK
                     SIKKNSMYAKASIIDPELMVTMPKHIIASVGFDALAHNMEAYLSNGRNPLADVQAIYG
                     IELISENLIKVYNDVNDLEAWEKITLASTIGGMTIGTAGTALPHGMEHPVSGLRDVMH
                     GKGLAALTPTIIESSWDSDIERFGNISKVLGGTCAEDCSDAIRNFLKKIDLDIKLSDL
                     GIEKSDIDWLTDNCMKISVANIKRHPKYFNKEQIKEMYHKSL"
     gene            complement(134160..134399)
                     /locus_tag="PC465_000275"
     CDS             complement(134160..134399)
                     /locus_tag="PC465_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2647611.1"
                     /translation="MKKEYGYPTLKVICQASAGNETAIREILKFYDAYICKLCLRPFY
                     HSESGKIIMQVDEELKGQIHTEMMKAILKFEIRVK"
     gene            complement(134404..134823)
                     /locus_tag="PC465_000276"
     CDS             complement(134404..134823)
                     /locus_tag="PC465_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008728841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2647612.1"
                     /translation="MNPSSFEHIVRIQFNALMMTVIKCTVKNRNRQFARRSKREVLFC
                     ELSDTKNVECVTKDNYSCDYISFEVLNFTIQISNEKLAVALYKLSNKERDVILLRYFQ
                     SMSDQEIAELYHVSRSAIYRRRSNGLKKLKTVLKERN"
     gene            complement(135015..136400)
                     /locus_tag="PC465_000277"
     CDS             complement(135015..136400)
                     /locus_tag="PC465_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2647613.1"
                     /translation="MNKNIDFVNGNTKKCLLEMTVPMIIAMFLNMAYNLVDSLWIGNL
                     LGEQAYAALTNSTPIILILTSIGMGATNGLAILLSQVIGAKNEQKKKNIIVTSFFVSI
                     ILSVFMTIVLEIFLEPILIVLNTPTEIFDMAKNYLSIYALGYVAVYLYLYFTAILRSF
                     GNTMFQAVAMLVSTLLNAILDPIFINIIGFHGAAIATLISQIICLAFMCIYIYHKKLF
                     NLSLSDFDTKEIMPFVKNAVPSVIQQSIPAISTTFLTAIVSTYSISAIAGYGVAGKLE
                     MILFYPAMALNMVLTSIVGQCIGAQRIDRAKNYLKLALKYGIVVSSVLSAVVIFFSKQ
                     LAKLFVSNVAVTNVVSHYFLIVSIGYVLYTITSCYLGTLNGIGKPTKSMILMIFYYII
                     IRIPFAYLLSWLAENLNGVWIAILISHIVACIITILTSNQIIKRLYGKLYDRTKKARY
                     KSIESNCCGKF"
     gene            complement(136476..137036)
                     /locus_tag="PC465_000278"
     CDS             complement(136476..137036)
                     /locus_tag="PC465_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008728836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2647614.1"
                     /translation="MRISKEPEERKQEILETAIKLFSVNGFEKTSISDIAKEIGIAQG
                     LCYRYFPSKDVLFQSAINEYSNILVANMTKNINIKKDSLKDILRKMILFAEQEDDTYY
                     PVFHNNQNKNFHNLLTLNVCEKLFPIVSEIIERANYTNEIQVNDVEMYASFCIYGQLG
                     IILNTDISIKEKSSRIKAFFRDLFRL"
     gene            complement(137060..137671)
                     /locus_tag="PC465_000279"
     CDS             complement(137060..137671)
                     /locus_tag="PC465_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008728833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2647615.1"
                     /translation="MNITKQKSQKTFDKQAADYDTNIQGEHARKLYKPIIENLKNKNI
                     HSILDLGCGTGALLKEIKELNIAEQLFGIDISPNMLEIAKNKLGNDATLILGDSERLP
                     FEDSSFDAIVCNDSFHHYPQPDIVEKEVSRCLKQNGVFIIGDCWQPIGARQIMNYYMK
                     HSNSGDVKIYSKKEMLLLLSKDFHEIEWKSFGTRSCLIIAYNN"
     gene            complement(138022..138657)
                     /locus_tag="PC465_000280"
     CDS             complement(138022..138657)
                     /locus_tag="PC465_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2647616.1"
                     /translation="MEHYEKKVSFLGENIQTIRKHRGMKQQELADKIGINMQSLSKIE
                     RGVNYPTFDTLEKIMDVLGVTPNELLSGEWKYVNQAEKEVCQFLRIEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIVASDLYPIKEFIQHLKFQKLLERYDD
                     LYSMDMFGESIEGHKYRTPYQVVKMINPNAKEDMELLREVLKNNHFDDEDE"
     gene            139124..140215
                     /locus_tag="PC465_000281"
     CDS             139124..140215
                     /locus_tag="PC465_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018594174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDF2647617.1"
                     /translation="MTTHKNLSVKIDYISIVFETATAEDVIMHILDLPTDIFNVYPAT
                     IKFKTYQARWQIGDIYVSGDARKTEDNPQGLGCYLVMTGRGCDDIFRILDSRNYTFGD
                     MFRRCERRYGLDNFHFTRLDIAIDDKNEKPFFTIEQIKKKCEKEEFISNSEGYHFDES
                     KFDDFDTAKTVYIGAGKSGLSYRFYDKDKEVCSKHNKTLDEVGSWKRTEMQLRDDKAH
                     AFAMTFKDRPLELGELAFGLLANNLRFVVPNRNESNKSRWKTCRFWERFLGAVEVLKL
                     QVPKLHNSLEETQQWLTEGGVISAVKSFYFLEEHDALGGLEKVGTMLDKARYSNSLSS
                     KLTAHLQRIDRTDLIPYIQYDTKHGKGGI"
     gene            140215..140418
                     /locus_tag="PC465_000282"
     CDS             140215..140418
                     /locus_tag="PC465_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDF2647618.1"
                     /translation="MNNNDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWLI
                     MNGNRIQIKRRQFEQVIDKLDAI"
     gene            140497..141690
                     /locus_tag="PC465_000283"
     CDS             140497..141690
                     /locus_tag="PC465_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF2647619.1"
                     /translation="MKEKRRDSKGRILHTGESQRTDGKYLYKYVDAFGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRANVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDCVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKYYDDVLI
                     LLKTGLRISELCGLTIMDIDFIHEVVVINHQLLKSKEQGYYIETPKTKSGTRQVPLSR
                     ETIQAFQRVIKKRPKAEPFVIDGRGNFLFVNHKGKPKVAIDYNMLFVRIVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            142030..143052
                     /gene="splB"
                     /locus_tag="PC465_000284"
     CDS             142030..143052
                     /gene="splB"
                     /locus_tag="PC465_000284"
                     /EC_number="4.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore photoproduct lyase"
                     /protein_id="HDF2647620.1"
                     /translation="MFNPKRIIFEKGTLDTDVGKKIYNKFRDNKDVEIINISSNRIKE
                     HIPGENLYEQYRSGKQTMVVGIRKSLKFQTCKPSANYQLPLVSGCMGRCEYCYLNTQL
                     GDKPFIRVFVNVDEILEQTKKYIEDRKPQVTIFEGAATSDPVPVEPYTNSLKKTIEFF
                     GREEKGRFRFVTKYSDVDSLLDAEHNNHTEIRFSINTPRIINEHEHYTASANKRIESA
                     VKLARAGYQIGFIIAPVFLYEGWKEEYKNLIISIKEALPKDFDKKIIFEVISHRYTTK
                     AKNRILEIYPDTLLPMENEDRKFKYGQFGYGKYVYDKEQLDDMKEFFLKEINGVFKNS
                     LIKYII"
     gene            143234..144145
                     /locus_tag="PC465_000285"
     CDS             143234..144145
                     /locus_tag="PC465_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2647621.1"
                     /translation="MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKR
                     LVNKTVMEYIKLRRLARASEYLAEHKNRILDVALNFGFASHETFTRSFKKAYGLTPEK
                     YRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPI
                     CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVE
                     VESGTSVEGYSTFELPAKEYLVCGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTD
                     FAIEMYYPTTPEAAYLEHWIVPVPIEQ"
     gene            144160..144576
                     /locus_tag="PC465_000286"
     CDS             144160..144576
                     /locus_tag="PC465_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HDF2647622.1"
                     /translation="MNWQDAFFQDTKPTFEQINEFINNPLWDKLNKTLVSTYNVEPKL
                     EYSKCSMQRGWNVKYKKRGKSLCTLYPQEGYFKALVIVSESNRVEVDLFINTCCDYIK
                     KIYNEVNFFNGSKWLMIQVDSLLVLNDMLELIKFRA"
     gene            complement(144676..145068)
                     /locus_tag="PC465_000287"
     CDS             complement(144676..145068)
                     /locus_tag="PC465_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2647623.1"
                     /translation="MSINTEKNITKNVEELTCPIRYALDIVGGKWKLPIICMLAVENP
                     IRYSSIKRKLDGITNTMLAQSLKDLESTGIVHRKQYNEIPPKVEYTLTSKGKSIVPIL
                     QQFANWGATNMQEKNTCGLSCKECRKIK"
     gene            145209..145604
                     /locus_tag="PC465_000288"
     CDS             145209..145604
                     /locus_tag="PC465_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HDF2647624.1"
                     /translation="MKALEFLNKARVYYLATVDENNQAHVRPLGFVMEYNGKLTFCTS
                     NQKDMFKQLIFNPKVELCCIDQNLNTLRILGEAVFVTSKETQAKALEIMPSLGQMYSV
                     GDGKFEIFSIDKAKVSCCSMSGKKIDVEL"
     gene            146007..146213
                     /locus_tag="PC465_000289"
     CDS             146007..146213
                     /locus_tag="PC465_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647625.1"
                     /translation="MSKYSSLWEYVKKNNSQSFKLTFEEIKDIAGIEIDHSFLKYKKE
                     LNEYGYQVGKISLKEKTVIFDKIG"
     gene            complement(146370..147101)
                     /locus_tag="PC465_000290"
     CDS             complement(146370..147101)
                     /locus_tag="PC465_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647626.1"
                     /translation="MLSKKNVSLIILVIILSLLTAIFIFNNKNTNNKLKEVTKNNEEI
                     VPKNLEGLSIEQLIEIRDKAIDKNLEGLREFGEDSVKKRKDSILNFEFGLVAFVNKNY
                     SNLTEKEKLIRQINIVNYENSINDIMDPSGSFFELANQNYQVNEFLLKNGKDYKEWSY
                     EGLDFLIDHLEELCKFVDFDVKDVIDIIDPTIKTDLSEEQKKSLNDKLKKISSSDTLS
                     EEVKKEIKNWENNLNNLNMNKNNSN"
BASE COUNT        57758 a        16519 c        25415 g        47505 t
ORIGIN      
        1 tattaatatt cccttgaaat taaaaaaaca tagatatttc agtaatctaa aatagtctac
       61 aaaaataaca gttttagcaa aattaataag aatacatata gatttaaacc taaaagtatg
      121 aacatgtctg ttttttacaa gattaaaatt tatattatat gataaaatta acttaactat
      181 ttcaataaga cttataattt ttttctttat actagacctt attgaaacct ttatagttta
      241 attctaatta tatattataa ataaagtatg tgtatattaa ggaggtaata tgaagttttt
      301 aaatgtttta gtagtagttg aagatattga gaaatcaaaa aagttttatt atgatgtttt
      361 ggggttaaag gtaatctgtg attttggaga aaatgttgta ctagaaggta atatatcatt
      421 acaagaaaaa aagctttggt tagaatttat taataagagt gacagtgaag ttaagttcaa
      481 tggaaatgat gctgagttat attttgagga agataatttt gatacttttg ttgaaagatt
      541 gagtacaatg aaagatatag attatgttca tctagctata gagcataggt ggggtcaaag
      601 agcaattaga ttttatgatt tagatgggca tattattgag gttggagaaa ctatgtcatc
      661 tgtgtgtaga cattttttag atagtggtct ttcaatagat gaggtagcta aaagaatgga
      721 tgtaactgtc gaatatattg aatcagtttt agaatagatg gattatatta aagtaaaatt
      781 gaggtgaagg ctgtaagtaa acttgtgtga aaacaaattt gcttacagtt tttatttttc
      841 taaaataaag aatataatac ttgtttagct ttatttgagt ttttaaaaat attatgatat
      901 ttcttatata tttatactaa agtttaaatt tagaaaaaat atataaaaga tagttatatt
      961 tactattatc ttgtataatt atatatacta ttttatataa ctatgctaaa atttaattga
     1021 ataaattaaa aatataatga aagtttagtt ttaattcatt tatttaataa acatttcaag
     1081 taaaataatg tttaaatcag aaatataaat aaatattatt ataatcgtta ttaaagacca
     1141 aaaatcccat cttagaagtt tgtatcatat gaaaccttta tagattatga aagcaataat
     1201 atagtgtatg atatataaaa taagttataa aagtattttt ttagatattc aaaaagacat
     1261 tgtaagttat attaataata tgggtatcaa cgaattttgg atataatgag ttttttaact
     1321 taaagttatg taataatgaa tgtaaagaat atttaatgaa atcattttgt tggttatgtc
     1381 tagctgaata caataatctt ttagataaag attttatatt tgaagatagg tgtgaaaaaa
     1441 ttaagaagat attaacatca gcagtttaga ggcaaagcat gtaaagtaaa gtctgggtaa
     1501 ctaaaagtag taatttagat tgtaactatt gttataaata tgaaaatgag gaaacaggaa
     1561 atataagtta ggatgtagaa aataggttac taaataaaaa gcttaattat ataatcaaag
     1621 aaataggtat atactgtaca atttcatggt gaagaacttt tcctaaataa aaaggttggt
     1681 aaaagagata taagaaataa aattcaatta taagatatgg tatgataact aaaggcacta
     1741 tatggagtga ataggcggaa gaattttttg aaaattataa aaatagtttc tgttgctaca
     1801 tatcaataag tatagataga gattgcaaaa tccatagcaa aaatcgaatt tataagtgta
     1861 aataacatgt aagacaagga gtaaattatg agtattttag agataaaaaa cctaaataaa
     1921 atatatggta aatcggaaac agaggtgaaa gcgttaagtc aaataaatct aaaaataaat
     1981 agtggagaat ttgttgtgat agtaggtaaa agtggaagtg ggaaaagtac tttactacac
     2041 ataatggcag gacttgaaac tccaacaaat ggtgatgtga ttattgataa tataaatata
     2101 tcatctcttg atgaaaagaa aagatctgca ttacgtaaag aaaagttggg attaatattt
     2161 caatcatata atttgattcc agttttaact gttgaagaaa atataaaact accaactata
     2221 aatataaaaa ataaagatga agcttatatt aatgaattga tggagttact aggaataaaa
     2281 gatagaagaa tgtatttgcc aaatcaatta tcaggtgggc aacaacaaag agtagcaata
     2341 gcaagggctc ttgtaaataa accatcaatt gtatttgctg atgaacctac tggaaattta
     2401 gatacaaaga cagagtcaga tgtattaagt ttattaaaag aatctcaaaa aaaatataat
     2461 cagacaataa taatgataac acataatata gatataacaa aatatgctga tagagttata
     2521 gaaatagaag atggatttat aagagagtag gtagatttat gaaacttaat tatattgtaa
     2581 aaaaatatat aatgggaaat aagaaaaata cattattaat aattgtaagt attgtaattt
     2641 caacagcgtt gtttttaatt atgaatataa taagtgaaga tgcgacaaac ttaatgataa
     2701 atcaagctaa aaatgaattt acattaaaac atgcacaata tatcaatcca aaagacgaag
     2761 aaataaaata tatagaaaat aacacaagta tagataaagt tggaaaatca atgcttttag
     2821 gaattagtga tattggtaaa ggtcaaacac tacaaattct atctcaggat aaagttgctg
     2881 aagaactaaa tgatatttac acactagaaa aaggtaaatt accagtagct gaaaatgaaa
     2941 tcgctataga ttcatggtat attaaacaaa aaaagataaa aaaccctata ggaaaaagga
     3001 taacattaga ttatagaaga caagggatag atcaagaaga tttatatact ggggaaaaag
     3061 aatttaaaat aactggtatc ttaaatagta atcctatttt aaaagctcaa ggaacatcaa
     3121 ttggccttat aagtaacgat tgtgctatca agaatattcc tactaaaaat aaatatgatc
     3181 aaattatgtt tacttttaaa aaggaaaaaa atatacagag acaatcacaa aaacttatta
     3241 aaaatggaaa tttgaatgag aataacattt attttaataa tgaattatta atagctatat
     3301 ctgatagtat gaatttaaaa ataccttata taatagttaa tatagtacta gcactagcaa
     3361 ctatattatt aatttataat attttttata tattagtatc aaatagaata aaggattttg
     3421 ggatatttag ggctttaggg tttaatccaa atgatatttt taaaataatg attttagaag
     3481 tatctatata ctctattata agtatttcta taggtctaat tttaggtggg ataatagcta
     3541 gtttatcaag ggagtatgtt ataggagtaa tatacaatgt caactatata aattctataa
     3601 aaaaccagaa ctatataaac acatacataa tttctatatt attaagttta ggaactataa
     3661 taatatcagt ttcaaaacct cttatgttat cagttaaaac tgatccaatg atttgtataa
     3721 gaagaaataa tgaaaaagtg gatataaaac aaaattcctt tataaataaa tttatgataa
     3781 aacttttcaa agactatggt aacatagcat caaaaaatat acaaagaaat aagaaacgta
     3841 caaatttatc tatagcatca atggtaatta tatttttctt aatggcaaca atatacacaa
     3901 agtctactag taacttttta agtgatggtg tattaaaata ttggatacaa ggagattatt
     3961 tattacataa tattgatata agtactatac gttcaaataa taaaggttat gataaaaatg
     4021 tactacaaga gataaaggca attgatggtg taacaaaagt aaactcatat aggcataagt
     4081 ggtttaatat aaaaattgat gataaaagta taaataagaa ctctgattat tggaaaaaaa
     4141 ataaagataa tattgaagct agatcagaag taaaagatgg aattaaggta tataataatt
     4201 cttttgaatt tttaggaata gaagatacag atatactaga ggatttcttg ataaatggaa
     4261 aggaaaatat agataaattt agtaaacaac catatctgta tataacaaag aaatccagtg
     4321 attcgcttaa tataaaaaaa ggagatagaa taaaagtata ctttgatatt atagattcaa
     4381 aaacaaataa ttttaccaaa acaatatctc aagaatttat agtatgtgga attataacta
     4441 cattaccagt aacctcacaa gtgggagctg aatttggcgg agtaatatca acaaatcaat
     4501 ttaataagtt tacaggaata tcatcttatg aaagatttga catatggacg agtaaactag
     4561 ccaatgataa atatgttgaa agtgagttaa acaaaataac agaaaaaaca aataaaggaa
     4621 ttttaattcc atacaaagct gaaacagctg aatatgaaaa aattgataat caaaaaacac
     4681 taattatggt attagtaact ggaattatag ttatattatc tttatttaac tgttgcaata
     4741 ctatagttac tagtattaat agcagaagta gggaatttgc actatttaga ggaataggaa
     4801 tatcaaaaca tgaaataaat aaaattgtta aattggaaag ttatatatat attatagtaa
     4861 gcttttgtat atctataata cctattttaa ttgtaagaag tataataata aaaccttttg
     4921 aaagtatcaa tttaataaat tggaaattta taggggctat tatcctaata gtatttattt
     4981 tagtatctat aatcatgata actacactaa aaacattgaa taaaattcaa aatgaaaatt
     5041 ttatggaaga aataaagact ttatagtgaa cagcctataa attaaagagg ttttatatga
     5101 atttaattgc aattatcgat aatggtgtag atattgattt taaataattt agaaataaaa
     5161 ataaaataag ttatccaagt tatatgtatg atgtaatagg ggtacaatgt atagcaaata
     5221 taaatattgg cttaataaaa ctctactctt aagtctactg tcgttttaac acaagactaa
     5281 taataagtgt aacctaaaaa ttattgataa tacaataacc ttgtttatga taaataacaa
     5341 atattaagtg ttgtaaagat agtaagttta aaaaaatatc aaagatttca atcacaatgt
     5401 attgtttatc tgtagtgttg gttatttatg gtatatatgt atttataaat tgtactgaat
     5461 atatatatac tatgctatct acaaaacagt taacagtcac aggaaatgaa tataccatta
     5521 taaattatta tatgagtaac tttagtcagt atataatatt tgctatttta cttgcatcaa
     5581 tgggatttgt aatacaaaag atagtgcata tgcatttcag tgagatagaa cttagtggta
     5641 actattcaac aactgttaga aatataagtg atatctcttt agataatgat aatgaaatgt
     5701 ttaatagagg cagtattgaa aatagtattt taaaaaaata aataatataa atatataaaa
     5761 tgtgattgaa taaagcttag aatacttagt gtattttaag ctttttttat tattaagatt
     5821 tcaaagtatt aaattaacta tataaaatca tataaaaata attttaaaat atttaaatca
     5881 ttgatttcaa ggtattgtat ttttaaaaga gtaaaaatat aataagttag gtatataata
     5941 tatataaagt aaaaaataaa aaaatggaag tgattgagat gagtagtata ttgttggttg
     6001 aagatgattt aagtttgata tatggattag aatattctat acaaaagaat ggatttagtg
     6061 ttgatgtagc aagaacagta gaagaagcat tgcaaattta taaagaaaaa aattatgatt
     6121 tactgctttt ggatgtatcc ttacctgatg gtgatggttt tgatatttgt aaaagggtaa
     6181 gagaagcttc taatgtacca atcatatttt taactgcttc tgatgaagaa gtaaatgtag
     6241 tgatgggact tgatatgggt ggagatgatt acataacaaa accttttaaa ttaaatgagt
     6301 taatttcaag aataaaagct ttacttagac gttataattt tacaagtgaa aatgtaactg
     6361 aactaaaatc aaataatatt actgttaaat tacttgaaaa tcgtgttttt aaaaatgaaa
     6421 ttgagcttga gcttactaca gcagaatata aattattatg cttacttatg aaaaataaaa
     6481 atattgtact tacaagaaaa aatatattgg ataagttatg ggatggaaat ggtagttttg
     6541 tagatgataa tactctgtca gtatatgtaa gaaggttaag aaataagatt gaagataatc
     6601 ctgaaaatcc aaaaaatcta ttaacagtta gaagaatggg ttacaaatgg aatgttataa
     6661 agtgagggtg ttaatatgaa ggtattttct aataaagaca taaaaatatt ttttttggtg
     6721 attatatccg ttttattgat gtttatagta gtaggtcaaa tagtagttat aaatataact
     6781 aatgattata aaagtgcact gttagaacat gattataata tagctggata cttaaatagt
     6841 atgggtgttg ataaatcaaa aataccagca gtatttacta ctaatgaaga taaatatact
     6901 ttaaaaggaa aagaaatctt aaatacagct agatatgact ttggtacaga tgatagtttt
     6961 atgccaagtg tgaaattgtt tcaaggtaaa tatataaaaa ctatgttttt gtatttattt
     7021 gtgttcttta ctatgattat ttttatattg tatgtgtatt tttttaggca acagaacaag
     7081 atagaagaag ctagttataa aattgattca tttatgaatg gaaatataaa tgtacggtta
     7141 aatacttatg aagaaggtag tttatcaaag ttatttggtt caatagatgc tatgtcaaca
     7201 tctctaaaca cacatatatt gaaagaaaag cagaataaag aatttcttaa aaatacaatt
     7261 tcagatatat cacatcaact aaaaactcca cttacagcat tgatgatgta taatcaaata
     7321 ttgcaggaag agagtcataa tagtgaaatt gttgagaatt ttgtgcagaa gagtcaaaat
     7381 gaattagagc gtatagaatc attgatacaa aacttgttaa agattacaaa gatagattca
     7441 aagacaataa ttcttaacaa agctagtgtt aacgtaaaaa agttgattac taaaatttta
     7501 tatagttttg aaactagagc agaaaaagaa ggaaagagta tctctataag aggtctagaa
     7561 aatacaaact tgttttgcga ttatgaatgg atatcagaag ctttaagcaa ccttataaaa
     7621 aatgcattag ataatacaaa agagaacgat aaaataatga tagaatgggt tgaaacacct
     7681 ataacaacta ttatttcagt gagtgatacc ggaaatggaa ttcatattga agatatacat
     7741 catatattta aaagatttta taggagtaag ttttcaaaaa gtaatcaagg ccttggatta
     7801 gggttgccac tagttaaatc tatcatagaa cagcacaatg gaaccataac tgtagaaagt
     7861 aattttttac aaggaagtac atttactcta agttttttaa agcttactaa tatgtaagat
     7921 aggatacatc ttacagtaag gtgtatgaat tattcttata ttaatcatca gaaaggagat
     7981 agagcaaatg gatattcttg tggttaataa tttatgtaaa acatatggaa atggatatac
     8041 aaaagtagag gcattaaaag atgtatcatt tacagtttca aagggagagt ttgttactgt
     8101 agttggagaa tctggctcag gtaagagtac attattaaat cttttaggag gtcttgatac
     8161 tccaacctca ggaaaaatat ttgttgatgg taaagaaata tgttcaatga aagaagaaaa
     8221 acagactatt tttcgacgtc gtaatatagg ttttatcttt caatcatata atcttatacc
     8281 cgaattaact gtggaacaaa atataatatt tcctttacta ctagattaca aaaaaccaga
     8341 cactatttat ctagatgaag tattgacaat tttaggtctt aaagatagaa aaagtcatct
     8401 tccaaatcaa ttatctggtg gtcagcaaca aagggttgca attggaagag cattgattac
     8461 aaagccatca attatattgg cagatgagcc aacaggaaat cttgacagta aaaatagcag
     8521 tgatgtaatt tcacttttaa aagtgacagc agaaaaatat aaccaaacta ttattatgat
     8581 aactcataat acaaatatag cttctacagc agataggata ctacaggttt ctgatggaat
     8641 gcttaaagac ctaggggtga atagagaatg agaagctatt tagaactagt accacaatat
     8701 gcaaaggtac ataagaaaaa aaatagaact acaattttat gtattgtcat tgcagtatgt
     8761 ttagttactg ctatttttgg actagcagac atggctatac aatgtcaaaa agtacaattt
     8821 ataaaagatg atggaaattg gcacatagta cttaaaaatc ttaatgaaga agctatatca
     8881 gaaataagta gtagagtaga tatagctcac tatggtagag gacaagtcat tgataatgga
     8941 gagtttaaat caaaggagat tttgatacaa ggtttagatg aagatttagc aaaacaatta
     9001 ggtctagaaa taataaaagg tcgttatcct gttgtggaga atgagacttt aatagatgta
     9061 gatgcagtta aaagctttaa tctaaaagta ggagatttta tcaaaataaa attagcagat
     9121 ggtagaaata aaaattataa gatagtaggt gaatattcat cattatcaag cttaagagcc
     9181 tcagataagc atggattaat gctttcaata ttaggtacac aagctatcaa aaaatcagaa
     9241 acatatgatt attattatat tacatttaaa gacaaggtta atattagaaa agctacttct
     9301 gatattaaga atacctttaa tttaagtgat aaacaaatcg gtaaaaatga aaaattactt
     9361 tctattatag gtcaaggtga ctctgattat tctaaaccac tttacttaac agcaggagga
     9421 ctttttatac ttgtgttaat agcaagtatt atcatgatat ataatagctt taatatgggt
     9481 gtaatagaga gaataaagtt ttttggacta ttacgttgct tgggagcatc aaaactccaa
     9541 gtcaaaaaat ttgttgtttt agaaagttta attctaagtg taaaggctat tccactagga
     9601 ttgttattag gatgtattgt aaccattata tcctctatat ttctcaaata tgtgaataca
     9661 gagttatttg gttcgatgcc aattttaaag gttagcttta ttggtattgt gtttggaata
     9721 atagtaggat ttttaacagt aatattatca gctattgttc cagcaaaaaa agcttctggg
     9781 gtgtctccac taagtgctat acgtggtaat ctaatgttca aagaaatttt aactagtgga
     9841 aaagcaagta aaattgctaa cgcaggaagt tctaaaattg atgtttctat gggaataaat
     9901 catgcctttt caagaaaaaa atcttttata cttatgactt cttcatttgc tattagtatt
     9961 gtattgtttt taggttttag tgtatttata gactttatgt atcaggcact taaacctata
    10021 aaaccagaag ctactcatat atctattgtt gacgctgact ttaagtctgt tcttactaaa
    10081 gacgatatta atgaaataag taatatcaaa ggaataaaaa aagtatacag tagaatgatg
    10141 acggatgtag aggctacata caataataag gaggcaacat ctcagctaat ttcttatgaa
    10201 aaaaatcaat ttgactgggc caaaaagtat ctagtaaaag gggaaatcaa tgaagataaa
    10261 ttagagtcag aaaatatcgg attggtagaa gaaggtcatg ggtttaatat tggagataag
    10321 atatatatta aaaatggaaa ttctaagaaa gagatagagg tagcaggtat actttcttca
    10381 atttcatttg atgttaaaga caaatatatt ggaaatatta taacatctga aaatactttt
    10441 actagtataa cagatataaa agactatata ataattgata ctcaagttga tgaagatgct
    10501 cctgaagatt taatccaaaa tataagaaat gttctagatg ataatttaga ggttcgagat
    10561 aagcgacaag gtaacttaga ggctaaaaat tcattttaca ctatggcagt ttttgtatat
    10621 gggtttgtat ttataattgc gattataagt atgtttaata tcataaacag tatgaatata
    10681 agcgttacaa gtagaataaa ttactatggt attatgcgtg caataggcat gtccaataag
    10741 caattaagaa aaatggtaat agtagaatca agtacatatg ctgtaagtgg ctgtttattg
    10801 gggagtgtac ttggattaat attacataga tatatatttg tatccttagt aacattaaaa
    10861 ttccatatag actggcaaat accttttgat ttactgttta tcattgtagt aactatgata
    10921 ataataactt tgcttgcagt aagaaaaccc attaaaaaga tttgtgaatt agacataata
    10981 gaggtagtaa atgcacaata aatataagta gtaatttaaa tagaggtagt aatttaaata
    11041 aaaaatcgaa gtaaatatga aatagaaaat atctttcata atttacttcg atttttgtgt
    11101 tatataattt actttagata agttccatct tcatcttgat aaattaagtc tttcttcata
    11161 agtactccaa gagcacgttt aaaattttct tacttgaatt aaataagata gaaatatctt
    11221 taggatcaga tttatcattg aatctcatat atccatctga accttctaaa tagcttaaaa
    11281 tcttattttc taaggtatca agttcatctt ttctgtttcc tctaggagaa agtcctaatt
    11341 taccatcatc gtatattttt ataacatgta aattttcaag aacatcccca gcttttaatt
    11401 ctgtaaagta ttcattatga aggattacac cagcatattt attgtcaaca catatcatag
    11461 cagagttgtt ggtttggaat ccatatacaa ctccatttac aacatctcct acattgtaag
    11521 tatggtctgt ttctaaatat gaatctatgt ctgtagtagc agctattctt ccgcttttat
    11581 ccaagtatat atagaataaa tatttttcat ctctaaacaa tggataagtc ttagctttaa
    11641 aaggaactag tatgtctttt gtaagtccca tatctataaa agtaccaata tccgtgttat
    11701 caactacttt tagatacgta acatctccat ttctaattat ttctatagta ttagaaaaat
    11761 aatttttaaa tagtttgtaa aatattattg aattttttct ctcgaaatat ataatttaga
    11821 atcttctgat ttatttttat gctcgatttc cttatttttt ttcataaata tatatagagg
    11881 agctattaac aacattgccc ctaatcctat taaaactcta ttttgagtta taggttttga
    11941 aatatcttct gcccaagctt gttgtaacaa ccatgagcta cctaaaatag ctaccattgg
    12001 tataacagga ccaaatggaa tcttaaaaga ggccttaaca tctgttcttt ttcttaaaac
    12061 tattactgat aaacaagttg gtatgtactg agcaaatctt gcaattacac tcattactgc
    12121 aagttgttca aaacttccag ttagcacaag tggtatacaa caaattaaag atattattat
    12181 tgctacatat ggagcaccat atttatttgt ttttcctata aatgcaggaa gagaaccttc
    12241 ttctgctaga gaagaaccac atttaggagt tactattgat gaacctatat ttataccaaa
    12301 tatagatatt aatgttgcta cagatatgaa aactttacca taattgccta aaaatacact
    12361 tgaagcatct gcaattggaa tactgttttc aaatagtcta tctccaagta tacccataca
    12421 gacaatttga attaatatat aaattattgc acatataaat attgtggtta ttaatgcgac
    12481 tggaagattt tttttaggat tttccatttc tccacttgcc acaataaatg attcaaagcc
    12541 ggtaaatgcg taaaatacta atataatggc tggacccata ctagagttaa ctacatttcc
    12601 tgaaggaaca atatttacaa attttataaa gaatattcca actattataa aaactattaa
    12661 tggtactaat ttagctatag ttattacatt attcattatc tttgtgcttt taattccaaa
    12721 taagctattt attgaaagta gtgttacgag tattgcagct atataacctt tgtattcagt
    12781 ggcagattct ggccaaaatg aacctaaagc tgttgcaaat cctactgcta gagtagacca
    12841 tgatataatt ctaataaccc aagacattgt accaacttca aatcctataa aatctccaaa
    12901 agcttttttg gagtatagat atgctcctcc attcttatca aacatgcttc caacttctgc
    12961 aaaacataaa agtattgata gaactaagag tgtagcaaaa atgtatataa acatactgtt
    13021 ttgacctgct agattataaa ctttacctgg tagtaagaat atacctgaac ctattatgct
    13081 attaatccct aataatatca tactaaatag acctaatttc ttagcttttt ccatattaat
    13141 ttatctccta ttcttttatt aattactgta ctaattaaaa tacaaagtat tcattacatg
    13201 catcataaca cctattggta aacaatcttc atctatatta aagctagagg tatgaagagg
    13261 tgaaattaag cccttttcct catttttaca tcctaaatgg aagaatgctc ctttacaatg
    13321 ttctgtgtaa aaagaaaagt cttcaccacc taaagacggg tttggtctca atataaattt
    13381 ttcctctcca agtaattctt tagtatttga tataactgta tctactaatt ctttttcatt
    13441 tataacagca ggatagtttt catcacttac atgtaaagtc ccaacacaac caaatgcaga
    13501 tgcagtgtct ccaacaattt tagctatttt atcaatcata aagtttcttg ttttgctatt
    13561 taaggttctt aaagtgcctt ctaattttac atcttcacat attacattgt gtgtatcacc
    13621 accatatatt ttacctatag tcaaaacagc agcattattt ggttctaagt ttctacttat
    13681 tatagtttgt aatgatgtaa caatttgtga agctgtaact attgcatcaa taccgttttc
    13741 aggatatgca ccatgagctc ttttaccttt gatacttatt tttatagtgt ctacactagc
    13801 atttaatgta tcatattttg tttcgataag gcctgtttct atatgtggca taacatgaag
    13861 tccgaatata taatcggcct tgggattttc taaacaccca tcctcaacta aaaattttgc
    13921 tcctccaaaa ccttcttctg ctggttgaaa taagaatttt acatttacat taagtttatc
    13981 ttttattgaa tgtaaaactt tacatgctcc aagtagcatg gttgtatgtg catcgtgacc
    14041 acaagcatgc atttttccag agtgtattga tttataaggt atgttgtttt cttcttcaat
    14101 aggaagagca tccatatctg ctcttataca aatcgtttta tctgcacttt cttttaaaat
    14161 atatgccata attccattgt gttttgtaaa ttccatataa tcaattccga tttcttttaa
    14221 ataagaaatt accttctgtt tagtaagatt ttcttcaaga gctaattctg gaattttatg
    14281 taattctctt cttatgttta taagccatgg ttttatagaa ttacaacttt ctattacaaa
    14341 atcttttcct aattctttgg tttgatattt taatttcaaa gcctgttgca tttttattcc
    14401 tccaattgct ttttattgtt ttattaatat aataagcaat tattatgcca taattttcga
    14461 tggagaattt tgttttttat aagaatattg aataaatata atcatttatc tatatgtata
    14521 gtataaaaaa tgattgcata gtttcaattt tcagtaaaaa atattatttt gaagaaaata
    14581 tattttatat gctagtttat ataaaaaaaa taggaaataa aaaaattatc ctattcctat
    14641 taattcctat tatttatgta caaaataaat tataatttta gggtacttga aaaataaaaa
    14701 aacctattga aggagtactt taatcctgaa tagatttctt tgtttgataa attataattt
    14761 tatagacctt tatattttaa tttattgtaa aaatcttctc ctttttgagt tattttactt
    14821 ccatatcttc ctgaactaca aattataagt tcttcttttt ttagatattc aaatattttt
    14881 ttaatttttc cttctgtaat ttgaaggttc ttatcgagta gtgcttttaa aattaatcct
    14941 ctaccaatac caacatctga ttccttattt aaaattagta tctctaatat attcaatata
    15001 tcattcttac tatattttag ttttaatgat gtatttttgt tatctgaaga ccttaagttt
    15061 ggaggtaaat ctttctctaa tacaatatct tcacacataa tgtttaaata ggatgtaaca
    15121 ttttggagtt ctcttatatt acctttccac atatagtttt gtataagttt ttttgcttct
    15181 ggtgtgatta ttaatttctt attaattaaa tcttccataa taattaatat gtcttctttt
    15241 ctttctctta gaggaggtat atttattgga attgtattta atcgataata taaatcctct
    15301 ctaaattggc tattatcaat catttgttct aaattcttat ttgtagcaga tatgattcta
    15361 acatctatat taattacatt gtgagaccca acaggcatta tctgcttttc ttgaagaact
    15421 ctaagtagtt ttgtttgtaa ttctaaaggc atatcgccta tttcatctaa gaatattgtt
    15481 ccattattag caagttcaaa taatccttgt tttccatctt ttagacctcc agtaaaagtt
    15541 cccttgtcat atccgaatag ctggctttct aataaatttt caggaacggc tgcacaattt
    15601 actgctataa agggttgatt ttttctattt gagttgttat gtatagactg agctatgagt
    15661 tctttaccag ttccactttc acctctgata agtatgctta aatcagattt agaaaccttc
    15721 ttagctaaat ctatacattc aaacatttta ggactatttg tttttatatc cttaaatgta
    15781 tattttgcta tttgtccttt ttctcttaat tttttagtga gattttgttc taattttttt
    15841 atgtatgtta tttcttgtaa actataatat gtgcccattt tttcatctct attgtatatg
    15901 ttttttttat ttacatttat atatttctta ttgaatacga caactttatc tagtatctct
    15961 ttctcactca ataaaacttt taaactatct acaaatatat cctcaatgta ttttccatat
    16021 atatcctcat ttatgtctaa aatatctttt actttactat tatatgtatt tatttcacca
    16081 tcttttgaag taaataatat accatctttt gataaattca atattgtatc taattcttct
    16141 atttttaaaa ataattcctt atatttatct tttataccag tatctaaact tattatttct
    16201 tctgagtatt taactagatt agattgtatt tcctttgaat caatttgtaa taaatttatt
    16261 atttctataa atgtagaaat atctatatat ctgtgaccta aatcaaatat atctgagata
    16321 aagctaggta ctttttctgg aactcctgga gttatagcta tttttatatt tttatagtta
    16381 ttatcattca tatatggaat tggtctaata ttagtcactc caattttata aaataaactt
    16441 atagtttcta gagtagtttc atcagaatca tttacgatta gaacatttgt accctgtggt
    16501 aaagatagta gattataaat tttatcttcc ctaaaagttc ttcttaccac aatcactttt
    16561 ttcttatcta gtatattatt tataattttg tctaatcttt ctactgacat tactaatatc
    16621 acatcatcat ttataatatc attatcattt atttcattta tgaagtatct attaatattt
    16681 atagaatctc caaaaactaa tttcaaatta ttttctaaaa agtctattaa atcttttcta
    16741 ctatcattta ccagagctac tgattttttc atttatttct ccttatataa taaatagttt
    16801 ccaacaaaat agttgtataa agcaatataa ttttgataat ttaaatttat caaataaaaa
    16861 agaaagtgtc tataatgact ttataaaagt tgcattaaga cactttcttt cttataatta
    16921 aaaatcttgt caccaaatcc ccctaattgt tgcttaaaac ttaaactgta tgtatatttt
    16981 tcatttctat tcgattaaat tataatatac acccaaaaaa atttatttta ataaattcta
    17041 ttgataatat aattttgtaa atatagaatt atattaaaat aaattatata tgaaaatata
    17101 tatgtataag tttattctgc gtgagtagaa tgaatttgtc aagtttaatt tagttgtaat
    17161 tgtatctttt attaaaaata atataaatta aaacatataa ataaaatatt ttatacaata
    17221 tattgtaaag gaggtaactt tgatgaaagc agaaaaaaca agtatatatc caattattaa
    17281 aaataattta aacaaaatat caattgttga atataaaaag ggtcaaagat ttgtagcatc
    17341 agataaagac ttacaagaag tgttctttat aatagaggga gttgcattag tggagtgtac
    17401 tactagagga ggaaataaat ttcttgttga cattgtacct gaaaatgaat ttataggcaa
    17461 aatcagttac atatatgaac ataatttgaa atgtgatata tttgcaaaga ctaatataaa
    17521 attatttcga tttgaaaaaa atgtatttga agagttttat ctcaaaccag attttattgc
    17581 actatttcat agaaaatgta caagaagaat atatgaatta tataaaacca gaatggtaag
    17641 agaactattt tcttgcacag aagttattgc ctattgtata tcaaataaac aagaaaataa
    17701 tgtctgcaat ataaaagcta ttcgtaattt cagtgaaatc tattcaatta gtagaaaaag
    17761 tagataccat tctctgctaa agttaactga aaaggagata gtaaaaaaaa tgggtaatac
    17821 atatgaaatt ttaaactatg atgaattaca taaattggca tttgaagtaa aagaattttt
    17881 ggaagatgag taaaaattgt tacttaatca aaataaagta taataatttc tgtaaaaaat
    17941 agaaatagtc tcactgaaaa tcaaaaatac tttagttatt ttcaatgaga ctgtttagaa
    18001 atattgtata cttataatgt atagtataat tattaatcaa tttcctttac tatattaata
    18061 gcccattttt tagataatgc tctaggaaca ccaaatataa acttaaccac ttcttcacta
    18121 taagtgagca aaacgagtac aaatataggt gcacctttaa atgcagctat aaaagttaga
    18181 ggaatagaag ctaaccacat acatcctaat tctaaaaata gagcatattt agtatctcct
    18241 ccacttctta aaataccaat tataaccaat gtattaaaag atttaagagc cattagtatt
    18301 cccattataa agaatatctt agttatatca gaagctaagc tatcagaaac actaaacatt
    18361 tttaataata atggtatatt taaaattaaa ataattccaa gtattaaacc agctgaaaat
    18421 acaagtatag aaaacttttt agcatattca atggctcttt taatatggtc agctccaagt
    18481 tcatttccaa gcataataga tgcaccagat gcaatacata cagctgtcat tatgaagaaa
    18541 ttacctgtac tggttgctat ctggctagct gctatagcag aagtaccagc tcttgcatat
    18601 gcaacagaat acaggacagt tccaattgcc catacagagt catttacaaa tataggaaag
    18661 ctttttgatg aaaaagattt tataaaaatt ttatcaatag cttttagatt ttttagacca
    18721 aactttaata tatagtcttt tttataaagg taaacataag taatcattaa aattaattca
    18781 catattctag caataacagt agctagagca gcacctttta cacccaatgc aggaagaccg
    18841 aagttaccaa atataaatcc ataatttaaa ataacatttg ttacaagtgc aaatgcacta
    18901 caaatcatac ctaacttagg atttctaaca cctcttgaac cagtactaaa tacagtactt
    18961 acagcaatta atggataact aaatactgca atactaaagt aatctataca aagttttacc
    19021 acctcagaat catacgaaaa tatgtgtata attggctttg gtgttagtaa agcaggaata
    19081 acaaatacaa aacttaaaac aattgccaat acacaagtaa gacctgtgac ttttcttata
    19141 ttactcacat ccttctttcc ataaaactgt gaaataaaaa ctccagcacc tcctgtgata
    19201 ccagataagg acatattaaa aagaaagaaa aattggtttg caactccaac tgaagctaca
    19261 gatgtttccc ccaaactact tatcataatt gtatctatta catttacaga agtagaaatt
    19321 aagttctgta tgataatagg tatacataaa gatagaagta ttttataaaa tcttttattt
    19381 tcgtctttta aagaaaatag ttcttgcaaa taatcctctc ctttttacat aaattcttcc
    19441 cactcatcat atagagaggc aaggttattt tctaaattaa ttttttcttg gctaacttct
    19501 ttagctttat ctggattaga gtatacttct tcttgacata aaagtatatc taatttttca
    19561 atttcaatct ctaacttttc aatttctttt tctatatttt gtctttttat tctatttttc
    19621 ttttctattt ctctttgttc tctctctttt cttttttcat cttttatttg agttctagtt
    19681 ttttcttctt tttcttctat aatactcatc tcttggattt gccttttttt atctatataa
    19741 taatcataat ttcccagata ttcagtaatt ccattttcat ctaaaactaa aattttatca
    19801 acaacagtat ttagaaagta tctatcatgt gatattgtaa atatagtccc atcataatta
    19861 gttaatgcct cttcaaggac ttccttagaa tcaatatcta ggtgattagt aggctcatct
    19921 aataacaata agtttgcatt tgatagtata agtttaagta tggcaactct agctctttct
    19981 ccaccactca atgtagaaat cttcttaaaa acttcttcat ctacaaataa aaatgcccct
    20041 aacatatttc tcaaagtagt ttgagtaaga tgagtattat tttcccaaat ctcatcaatt
    20101 attgtgttat ctaaattaag agttttttgt tcctgatgga agtaggaaac atgtacatta
    20161 gttccaaatt taatattgcc actaagaggt tgtagttcat tagttattat tttaaataat
    20221 gtagatttgc caacaccatt tgcacctata agtgcaactt tttcccctct atatatatct
    20281 aaatccaagt ctttaaaaag tattctttct ccataaccca tagatacatc tctaatttga
    20341 agaacatcat taccactctg gacagaaggc gtaaattgta tacgagcttt tttcctataa
    20401 gcttctggtt tatctaaaac gtctaccttg tctaatgctt tttctttact tcttgcacgc
    20461 tttaggtgtt tttctctacc ataagctttt agtctttcaa ttgattcttc ttgctttttt
    20521 atttcttttt gttggtcttc aaatttctta agctctagtt ctttttctat tttagataac
    20581 tcaacaaatt tagagtagtt accattatat actttaagtt ttttgttgtg aacttcaaaa
    20641 attctattta cggattggtc taagaaatat ctatcatgag atattaacat gacagtccct
    20701 ttatattgtt ttaaaaatac ttctaaccat tctatcgctt cagagtctaa gtggttagta
    20761 ggttcatcaa gtaacaatag agttggtttc ttaagaagta attttcctaa aagaactcta
    20821 gttttttcac caccagaaag tatgcttatt ggcttatcca tatcattgtc actaaatcct
    20881 aatcccttta gaactccttt ggcttcagat ttatatccat atccatttaa atctgaaaat
    20941 aattctagtt tatgtgaata ttcatccatg attttttcta taattggaga gtttgttttt
    21001 gtactttctt cagatatttt aacctctaat tctcttaaat aggattccat ttctatcaaa
    21061 tttttaaaaa cttctagtac ttcttccaaa atagtattat ccgaataaaa attggtattt
    21121 tgttctaaat atccgatttc acaatcttta gaagtgtaaa tatctccact atcatatcca
    21181 taaattcctg aaattatttt aaataaagta gtttttccag taccattaac accgattata
    21241 ccaattttat cgccttcatt tactgtaaaa ctaatatttt ctaatataga atctatacca
    21301 aaacttttat ttaagttatt acatgacaaa acaatcataa atttctacct ccttgaacta
    21361 tctaaaatta taatgttttg atataatata atcaaggtta tatgtattag ttttgaaaaa
    21421 gaaatatttt attgtgaatc aaacaaaaaa gaggacactt ttaggaggtg aagatgttgg
    21481 gaaataaaaa tatatcaatg gcagttataa gaaggctccc aaaatatcat agatatcttg
    21541 gagacttatt agatagggat atacaaagaa tatcttctaa agaattgagt gatataatag
    21601 ggtttaccgc ttctcaaata agacaagatt taaacaactt tggtggattt ggacaacaag
    21661 gatatggtta taatgtagaa gctcttcata ctgagatagg taaaattctt gggttggatc
    21721 gaccatacaa cgcagttctt gtaggagcag gtaacttagg acaagctata gccaattatg
    21781 caggatttag aaaagctgga ttcgagataa aagctttatt tgatgcaaat cctagaatga
    21841 taggtttaaa gataagagag tttgaagtat tagattcaga tactttagaa gactttataa
    21901 aaaacaataa tatagatatt gctgtattat gtatacctaa aaatggagca caagaagtta
    21961 ttaatagagt tgtaaaagct ggaatcaaag gtgtatggaa ttttgcacct ttagatttag
    22021 aagttccgaa aggtgttata gttgagaatg taaacttaac agaaagttta tttaccttat
    22081 cgtatttaat gaaagaagga aagtagacaa cttaaacata ttaataatga gcagttgtaa
    22141 agagtattga gaaagtcaga agatttaata ttaaatcctc tggctttttg aaatattagg
    22201 ataaaaattt aaataatgta tggaaataaa caatattaag gagagtggtt tttgtggagg
    22261 aattatggaa aaaggcaatt gaatttcatg gtcatgaatg tccagggtta gctataggat
    22321 ttaaagcagc acttgcagca aaaaaatatt taggatgtaa acagtcagga gatgaggaaa
    22381 ttgtatgtat ttctgaaaat gatgcttgtg gaatagatgg tatacaagta gtgctaagtt
    22441 gcacaatggg taagggaaat ttactactta ggatgactgg aaaatcagta tatcatttct
    22501 ttaatagaga aaatggaaaa tctataagga tatatgtaaa gtcaaaacca tttgagatgg
    22561 atagagaagg atacaaaaga tatttattag aaagtgattt tgaagaaata tttgagatta
    22621 cagatactaa gttaagactt cctgaaaaag caagaatatt taaatccctt aaatgtgaag
    22681 tgtgtggtga atttgcatct gagcaatata taaggattga agaaggaaag aaagtatgtc
    22741 ttgattgttt tgataaatat gaaagatttt atgaagagta ttaaaattat aaattagatt
    22801 aaagttaaaa gtattagata tgtgctaaca gtattttaag atgaattagg tagcaacata
    22861 ataaagtata taaataatat taattgaatc atacataatt aaaaagaggc tgattagtat
    22921 ttataaaata aaatcagtct ctttatgaat aacgaattat tattctggtt gaggtgcatc
    22981 tacaggacaa gctcctgcac aagaaccaca gtctatacaa gaaccagcat ctataacata
    23041 tgcgtcgtct ccagctgata tacagctaac agggcattca gcctcacaag caccacagct
    23101 tatacaagcg tcagtaattt tatatgccat tttgaaatcc tcccttttat atgtattgta
    23161 attcaataac attataacaa atattattga atataacaat taaattaatt ctacaacaaa
    23221 aactttatta tgatattctt gttttaaagt tttacaataa agtttaatct gcttatattt
    23281 ttatttattt taaagaagtt tattttaaaa ataaaattaa atttaaaaag ttatgtattg
    23341 attatattta aaaatgttat actctaaaaa agtatatttt atttaaaaat ttattaatac
    23401 aaaggagatt tactatgaaa aataaattag tttacatatg tattatgagt ctattgctat
    23461 ttgtagtagg atgttctaat aatccaaata aggaaagtac cattaaaaaa gactctaaga
    23521 ataaccaaag ccaagttaaa gaagaaaaaa gagaacctgt gaaaaaagat ataactataa
    23581 gtttcgctgg tgatgtaact atggggaact ataaaggttc atcatattat ggcagttttg
    23641 accatgaatt taaaagacaa ggagaagatt acaattattt tcttaaaaat gtaaaacctg
    23701 tatttgaaaa agatgactta acagtggtta atttagaagg tccacttact acagcgtcaa
    23761 atgcaaaaga aaaaaaattt gcatttaaag gaaagcctgg atatgtaaat attttaaaat
    23821 ctggaagtgt agaggcagta agtattgcaa ataatcattc agaagattat tttgaagaag
    23881 gaatgaaaga tacacagttt atattggacg agaataaaat aaattatttt ggattaggga
    23941 aagatgctgt tgtagatgtc aaaggaatta aagtgggtct attagggtat aatggattat
    24001 caactgaata taatgaaaaa aatttaaaac aaatggaaga tgatattaag tccttaaaaa
    24061 agaaatcgga tgttgttgta gtgtactttc attgggggat agaattagat tattatccag
    24121 ataaaaaaca aaaagatttt gctcattatg ctatagacaa gggagcagat ttagttatgg
    24181 ggtctcaccc gcatgtgatt caaggaatag aaaagtataa aaataagtat atagcttata
    24241 gtctagggaa tttttgcttt ggaggaaata agaatccttc tgatacagat agttatatat
    24301 atcaacaaac ctttactttt tcagataata aattaacttc aattaaagag ccaaatataa
    24361 taccaacttc aataacatct agtaactcca gaaataatta tcaaccaaaa gtattggatg
    24421 gaagtgagaa ggatagagtt ttaaataaac ttgaaaaaat aagcaaagat ttaaataaat
    24481 aaaatgtaaa aaaaaataaa tatatatatt tattttaata atttatattt tgtttagggt
    24541 atggtaaatc gtggtattaa ataagtagat tttaatagtt aaattatagt caattataat
    24601 aaagctattt aatctacttt tttaatataa aaatataagg gggaatttgt aatggcttgt
    24661 aacacttgta aaatgtgcga aagtgcagac aagaaattag aaagttttgt agcttcaaag
    24721 gatgttgaaa cagcatttca tagaacagaa gatcagaaag ttaagtgtgg ttttggactt
    24781 cagggggttt gttgtagact ctgttcaaat ggaccatgta gagtaactcc taaatcacca
    24841 agaggtatat gtggagcaga tgcagacact atagtagcaa gaaacttttt aagagcagta
    24901 gcatcaggag cagcttgtta tttacatgtg gtagaaaata cagctaagaa tttaaaaaat
    24961 gttggaataa ctaaaggtgt tgttaaagga gaaaaaacat taaatcaatt agcagagatg
    25021 tttggaatag aaagtgatga aaagtatgat aaatgtataa aggttgcaga caaagttatc
    25081 aacgatttgt ataaatcaag agatgataaa atggaattag tagaaaaaat agcttatgca
    25141 cctagagtga aaaagtggaa agagttaggt ataatgcctg gtggtgcaaa gtcagaagtt
    25201 tttgatgcaa tagtaaaatc atcaacaaat ttaaatagtg acccagtaga catgctagtt
    25261 aattgtttga acttaggtat atcaacagga ttatatggtc ttacactaac taatctttta
    25321 aatgatgtta tgttgggaga accagttata agaatggctc ctgtaggatt taatgtaata
    25381 gacccagact acataaatat aatgataaca ggccatcaac attcaacatt tgcaaatttc
    25441 caagatagat taaaagatga agatgttata aaattagctc aatctgttgg tgcaaaaggc
    25501 tttaagctag taggatgtac atgtgttggt caagatttac aattaagagg agaacattat
    25561 caagaagtat ttgctggaca tgcaggtaac aattttacaa gtgaggctgt tttatcaact
    25621 ggagcaatag atatagttct ttcagaattt aactgtacta taccagggct tgaaccaata
    25681 gcagataaat ataaagtaaa aatggtttgt ttagatgatg ttgctaaaaa agcgaatgca
    25741 gaatacatag gtttagacag aagtaaatta gatgaactta gtaacacttt aatagaaaaa
    25801 gcattggagt cttataagga gagaagagga agtattgaaa tagatatacc aaaagaccat
    25861 ggatttgaac aatctttaac tggtgtaagt gaaaagaacc tgaaagcgtt tttaggagat
    25921 tcatggaaac ctcttattaa tttaattgca gaaggaaaaa ttaaaggtgt tgcagctgtt
    25981 gtaggatgtt caaatatgac agcaggagga catgatgtaa atactgttga acttactaaa
    26041 gaattgatta aaaaagatat aatagtacta tctgcaggat gttctactgg aggattagaa
    26101 aatgttggtc ttatgtcacc tggagcagaa gaattagcag gagaaaactt aaaagaagta
    26161 tgtaagactt taggaatacc accagtatta aactttggac catgtctagc tataggaaga
    26221 ctagaaatag tagcaacaga attagcagct gaacttggaa ttgacctacc acaattacca
    26281 ttagtgcttt cagctccaca atggttggaa gaacaagcat tagctgatgg agcgtttggt
    26341 cttgcccttg gcttacctct tcatttagct ttacctccat ttataacagg aggaaaattg
    26401 gtgacagaag tattaacaga aaaattaaaa gacttaacag gaggacatgt tatagtgaat
    26461 ccagacccta aatcttcagc taatcaatta gaagaaataa taatagatag aagaaaaaat
    26521 ttagggttaa aggatgtgga atgcaatgca tagaattttt ataaataaag atttatgtac
    26581 aggatgtaag agctgtgtac tagcatgtat gctaaaacac aataaagatt atgacatgta
    26641 cactcttgat ttagaaaata tagataatga tagtagaggg catatagaat tagatagtaa
    26701 acataataat ccagttccaa ttctttgtag acactgtgat gaacctgaat gtgtattagc
    26761 atgtatgagt ggtgcaatgc ataaagatag tgaaagtgga atcgtttcat atgatgaaga
    26821 gaaatgtggt tcatgttata tgtgtgtaat gtcttgtcca tatggattat taaagccaga
    26881 tgatagaagc aagcagaaca tacttaaatg tgatttatgt aaagatgagg agtatcctag
    26941 atgtgtagct aattgcccaa gtggagcaat tgaattacag aaggaggaaa atgatgaatt
    27001 atgtagtgtt aggagctagt gcagctggta taaatgcagt aaaaacatta agagaattag
    27061 ataaagattc aaatatagta gtaatttcta aagatgaaaa cgtatactca agatgtatgt
    27121 tgcatcacgt tatatctgaa cacagaactt taaaacaaat aaattttgtt gatgaagatt
    27181 ttatggagca aaataatgta aaatggattg caggtaagac tgttaaaggt atagacataa
    27241 ataaaaaggt agttcagaca gaagacatta ctgtaaatta tgataaactt ttaatagcta
    27301 caggtgcatc ttctgctatt cctcctataa aaaatttaag agatggaaat tttgtatatt
    27361 ctgtgagaaa catagatgat atttataaaa taaaagaaaa agcacaaaat tctaaaaatg
    27421 tagttataat aggtgctggt ttagttggta tagatgcatt agtgggatta tttaaatatg
    27481 agcagttaaa tatttctgta gcttttatgg aaaagtacat tttagataga caattggatg
    27541 aatatacagc atcagtgtat gaaaataagt tcaaagaaaa aggtgtaaaa ttttacccaa
    27601 gtgcatcaat acaagaaatt gtattggata acagtaagaa tgttacaggt gttgcatttt
    27661 caaatggtga agttttagat gcagacatgg taattgtagc tacaggggtt aaaccaaatg
    27721 ctgacttttt agatggaaca ggaatagaat atgatagagg tataataata gatgatatgt
    27781 gccaaacaac acaaaaagac atatatgcag caggagatgt tgtaggtaaa aatgctattt
    27841 ggcctctggc agtaaagcaa ggaattgtag ctgcctataa tatggttgga aaagataaga
    27901 agatagaaga tgaatttgct tttaaaaata gtatgaattt catggatata ccaactattt
    27961 ctataggaat gaatacacct gtagatgata gctataaagt attaaccaga catggaatta
    28021 atgattataa aaagtttgtt tttaaagata atgtaatcta tggagcagtt atacaaggag
    28081 atatttcata tgtaggtgta ttaacttatt taataaaaaa taaagttgaa atatatgatt
    28141 tagaaaatag gatatttgat atatgttatg cagacttttt taatataaaa gaaaatggag
    28201 aattttgtta tagtgtatag tatatacgtg gagtaaggtt tataaataca gtaaatcaat
    28261 aaatagagtt attctaaaat aagaaaaatg acaaatctta tttagaaata gctctatttt
    28321 ttgtaattaa atttaaatta tattcaattt gtaaaatatt attttgaaca attatacata
    28381 tactctctag ttagaggtaa atcatttttt atacctttag tgaaaagtat ttgatgtata
    28441 tctataatac cagtgttgaa agcagcagca caagaacaaa ggtataaatc ccacattctt
    28501 ataaacttat catcaaacat ttctttaatc tttggaagat tctcagagaa atttttttgc
    28561 cagtatagta aggtttttac ataatgtaat cttagacttt ctacgtctat agtatgatat
    28621 ttgtaatcac tacaaatatg tatcatttct cttaggctag gaataactcc tcctgggaaa
    28681 atatattttt ttatccaagg gtctccataa gattcctgca atccacttat atagtgaagt
    28741 aaaaacaatc caccatcttt taaaacagca tttacgtttt taatgaaaag ttcatagttt
    28801 tctctaccaa catgttcaag catcccaacg cttacaactc tatcaaacat aaggtctgat
    28861 ttttttaatt ctctatagtc cataagtctt acctcaagat agtcttgaag gttctcttct
    28921 ttaattcttg tgttaaattc cttaaattgc tcttcgctaa gtgtaattcc aacgccgtga
    28981 attttatatt tttttgcagc ttctattagt aaaaatcccc aaccacaacc aatatcgaga
    29041 aggctcatac cttcctctaa atttagttta gttaatatgt ggtgaacttt attgacttga
    29101 gcatcataaa gagtatcatt atcatttcta aagtatgcac aagaataact aagtgtctta
    29161 tctaaccata agctataaaa atcgttgcca atgtcatagt gggcatgtat ttctttcttt
    29221 tgatgtctca ttgaatttga tgagtgcaat agatgtttta cagctgaatt atcaatattg
    29281 aatttgtcta tttgttttaa aagtagattt aaagttaaga ataaatctcc ctcaacttca
    29341 atgtctctat ttatgtaggc ttctccaagt gctaaagatg tactttttaa tagttcagac
    29401 ttgctaatat cattatttac tataactttg aactgagggg agccctctcc aattagaaat
    29461 tcttcctcat ctttaagcct aactagaaat ggtgtttcac caaatctctc taaatagtct
    29521 tttaaaaaat tttttgtaat attcatatta ccagctcctt ctaatgtaaa tccagtaagt
    29581 ttccctgctt aaaatatatt atagtccttt ttttaaaaaa gtaaaatttt ttcaataaat
    29641 tttttattta aaggaaattt attttttata aagaaatttc atgttgtagt atattttttg
    29701 cttataaatt ttggtactgg atataatatt aaactgttaa tgatataata aatttaatct
    29761 ataaagtaaa taaaattttg taataaatag ttaaagctat tttataagga gatatgtagg
    29821 atggaagtat atgctttggt tgggtcaagt ggcacaggga agagctttaa ggctttagag
    29881 ttcgcatatg aaaatgatat agaatatata atcgatgatg ggattttaat atacaaaaac
    29941 aaggttttag ctgggatatc ggcaaaacaa gcaaatacta ctatagaagc agttaaaagg
    30001 gctatttttt ataatttgga gcatagagaa gaagttagag aagcaattaa aaaagaaaat
    30061 ataagaaaaa ttcttattat tgggacatca aaaaaaatgg ttaatcaaat tgtagagaga
    30121 ttgtcaattg gaagggtctg taagtttata aatatacaag atataagtac taaatatgag
    30181 atagaaatag caaaacaagc tagaaaagaa ggaaatcatg taattcctgt tccagcagtt
    30241 gagataaaaa gtatggcaag tggtcttagt ataaattctt tgaagagact ttttagaaaa
    30301 ggaaataata ggaatatggt agttttagaa aaaacaatta taagaccaac ttttagttat
    30361 ataggaaagt tttatattag tgctgatgta attaaacaga ttattgaata tgaagtatac
    30421 aactttggaa gcattgatag aataaataaa atcaatatag agaattgcaa taattttatg
    30481 aatatttttg taagtataaa tatcaatgat ttagaaacta taaaaaaaat tgaagacata
    30541 caacagacaa taaaaaagtc tattgagaaa atgactttag ttaatgtaca aaaaatagat
    30601 attaacattc ataaaattaa aaaaataaac ttcctccaat gttaaaaaat aaactgagaa
    30661 aatgatatac taatttgcaa taaagtgtgc tataattaaa ctgtaaattt aggaaatggt
    30721 tttttctaaa tggagtatac ataattataa cgtatttata agggggcttt caaatgtcag
    30781 gaaaagatgt aaatgtcttc gagatggcgc aatctcaagt aaaaaatgca tgtgataaat
    30841 taggtatgga accagcagtt tatgaattat taaaagaacc tatgagagtt atagaggttt
    30901 caattccagt aaaaatggat gatggttcta taaaaacttt taaaggattt agatcacaac
    30961 ataatgatgc agtagggcca acaaaaggtg gaataagatt ccatcaaaat gtttcaagag
    31021 acgaagtaaa agctttatct atatggatga ctttcaagtg ttctgtaaca ggtataccat
    31081 atggtggagg taaaggtgga ataatagtag atccatcaac tttatctcaa ggtgaattag
    31141 aaagattaag tagaggatac atagatggaa tatataaatt aataggtgag aaagttgacg
    31201 ttcctgcacc agacgtaaat actaatggtc aaataatgtc ttggatggtt gatgagtaca
    31261 ataaattaac tggacaaagt tctataggtg ttataactgg taagccagtt gaatttggtg
    31321 gttctttagg aagaacagct gctactggat ttggtgttgc tgttacagca agagaagctg
    31381 ctgctaaatt aggaatagat atgaaaaaag ctaaaatagc tgttcaaggt ataggaaacg
    31441 ttggttctta tacagttctt aactgtgaaa aacttggtgg tactgttgta gctatggctg
    31501 aatggtgtaa atcagaaggt tcttatgcta tatacaatga aaatggttta gatggtcaag
    31561 ctatgttaga ttatatgaaa gaacatggta acttattaaa cttcccagga gctaagagaa
    31621 tatctttaga agagttctgg gcttcagatg ttgatatagt aataccagct gcattagaaa
    31681 actctataac taaagaagtt gctgaatcta taaaagctaa attagtttgt gaggctgcta
    31741 atggaccaac tactccagag gctgatgaag tatttgctga aagaggaata gttcttactc
    31801 cagatatatt aactaatgct ggtggagtta cagtttctta ctttgagtgg gtacaaaact
    31861 tatatggata ctactggtca gaagaagaag tagagcaaaa agaagaaata gctatggtta
    31921 aagcatttga atctatttgg aaaatcaaag aagagtacaa tgttacaatg agagaagctg
    31981 cttacatgca ttcaattaag aaagttgctg aagctatgaa attaagagga tggtactaag
    32041 atttactctt aataaataat aggatataat tatttaagat ataaaggggc tgtacatagt
    32101 acagccctta aattatgtgg cttacaatga agtaagctat ttttgtttta acttataaag
    32161 aacttgataa attatgtaat ttagaatgta ttttttacca ccacatgatt acaaattaga
    32221 ggagttagat tgaattttta gacatgaact tatgcatttt aaaagcaaag actttcattt
    32281 aaagtatcta gtattatttt taaaaatagt atattggttt aatccattta tatataatgg
    32341 aaaaatatat ggatttggat tgtgaatttt attgtgatga gagagtttta aaaaattgta
    32401 ctgtacaaca aaagcaagaa tatgctctaa ctattgtaaa ttcaatgaaa agaggtacaa
    32461 atttttcaaa taaatttgta gctggattaa ataaacaatc tgatattaga aaaagagtaa
    32521 taaacatgtt cagtgaaaaa tataaaaatg gtatcttaat ggctttgatt ataagcttgt
    32581 tttcttctat tacatttttt aaattcgatt caactagtat tattgaagag aatgatttct
    32641 tagagaggtc aagatatacg tttgaaggaa ggcaagaaga cgtgtttgta acaatagatt
    32701 ttatatatgc agatgcacct ataaaactta gaaaagagca tgaagaaaac tgtagagtca
    32761 atggaatagt accaaaagat tcagattcaa tagaaattat tcctagattt tataaagatt
    32821 gtatggattt aaaaaaataa gttagactta atattgatgt tgatattatg aattttttat
    32881 atttaagcaa ttgaaaattt tattatagat tcaattttat acgtgtttaa gtatgaaatt
    32941 tatagatagt tgaaataatt aaatatgatt gatgcatagg aatcattact aagctataat
    33001 taattatagg ggagtttaaa taaattatga gttacacaat tataaaatga taaaaatagt
    33061 tatctgttac aaaaaatgta tctttttaat taataaagat aatatgaaaa cttaaaaggc
    33121 aaataaactt aaacataaaa tactcttaaa taagatagga gaaaaatgta tgtctaactt
    33181 tattctaaat gggattttta gaacagttat agtaagtagt ctaagcattc ttatgatatt
    33241 gattttcaag aaaaatgtat ttaaaagatt tagcaaaaaa tttaattatt atatatggat
    33301 gatagttgtt attaaattat ttttaccatt tacatattat acttttacaa taaatatctt
    33361 gagaagtaaa aaacacatta atattaataa cataaattta gagggattta ataatgtttc
    33421 aactataagt aataatatta tattgtacac ttggattata actgtagtag tttatttaat
    33481 ttacactata tttaaatata taaaacttaa aaatttaata aatgacttat cttatgatgt
    33541 tgatgatgga gagattgtaa atctttataa aaatatatta gaagaattta atataacaaa
    33601 agatataaaa ctcaaatact cttatgaagt tgaaacacca gcatttttta attcatgtgt
    33661 gcttttgcca ccacatgagt ataaattgaa agagttagac tggattttta gacatgagct
    33721 tatgcatttt aagagtaggg acctttattt aaaatatgta atcctgtttt taaaaacagt
    33781 atattggttt aatccattta tatatataat ggataaacat atagatttag attgtgaact
    33841 ttattgtgat gaaagagttt taaaaaatcg aaattcagat gaaaaaaagg attatgcttt
    33901 aacaattcta aatgcaatga gaaaaggttc aaatacttca aataaattta tagctggact
    33961 ccataagcaa tctgatatta aaaagagagt tatgaatatg tttaatgaaa agtacaagaa
    34021 tggtatatta atggcattaa ctttatgttt attatcttct attacttttt tgaaggttaa
    34081 ttcaacgagt attgttaatc ttaatatatt gcctaaatat gatatggaga agctacatgt
    34141 ttttagagga agtgttacac ttttagaatt tacatatgca gatgctcctg aaaatgttaa
    34201 aaaagaacat aaaagaatgt atgaagcaat gggattgatt cctaaagact ctgataaaat
    34261 aagctttggt gtaaaatact atgacaagtt gaacaattta ttaagataga tatttatata
    34321 atagcaaata gctgaaactt aaaagaattt aaaagtaagt attcacaaaa gtcctaaaga
    34381 aagtattaat aattatattc aattgtaaaa aatttcacaa aacaaccaac ttttatagtt
    34441 atttcatcaa aaaatatacg ccatataaaa gcgcataaaa aaacacataa aacaatattt
    34501 atgcgcactt taacctcgaa tggtacaaaa ttctttactt ttacagaccc atattatata
    34561 attaagtaaa taatgtatat ttaggtgaca tattggataa gctaatttat ttattttatt
    34621 aatataataa tactataaaa gttatataaa gtggtttaca aaaaagttac agatagagct
    34681 tttattaatg tattgtgtat tagtatttta tccttaggta cacttcacct acaaaataga
    34741 atcataagat aattatggga aaattttagg aggtttatcg tgaagaaaaa gatattaata
    34801 ccagtatttg catcagttat ggcattatca gtaagttcaa ttgtaaatgc agatgaagta
    34861 aatgattcat ctcaaaataa ggatgataaa acaaatactg aattaaattt aggtgaatat
    34921 aaagaagtaa aatataaagt tgcaaaaata aaagatggag tagctataaa gataagagaa
    34981 gaaggtcaag ttcaaaacat agcttattct ggagatgaat ttacggtttt aggaactcaa
    35041 ggagaatggg ttaaggttaa agttgaagat ggcgaaggtt ggttagctac tagatatgta
    35101 gatatatctg aaggtgtagg atatactaac gctgataaag taaacttaag aaaagataag
    35161 agtgaaagtt cagaagtaat tgaagagctg gaaaaaggaa gttctttatt ggttttggaa
    35221 gataatggag attggttaaa agttaaagat ggggaaacag aaggatatgt aaaatcatct
    35281 tatatatctg ataaagctcc tgtaatagaa gagccacaag taaacccaag tattgaccaa
    35341 aatgtagatt ctacaaataa taatcaacaa aacaatgcaa atactaatca acaaaataat
    35401 aattcaaatg tgccaacagc taactctaat gcagttcaag ctgtacttaa cttggcatat
    35461 tctaagcaag gttgtccata tgtttgggga gcagaaggac caaacacttt tgactgttct
    35521 ggatttacac aatatgtgta tagaaatgca gtaggaaaga atataccaag aacatctaaa
    35581 gcacaatcta aatatggaca aactgtaagt aaagcaaatt tacaaccagg agacttagta
    35641 ttcttcacaa ctaatggttc tggttctgtt agtcatgttg gaatatatgt aggtgggggt
    35701 aatatgatac attcaccatc aacaggaaaa acagttagtg taactagtat aaattcatca
    35761 tactatacag caagatttgt tacagcaaaa agaatattat aatcggtttg taatatgaca
    35821 aattgataaa tacataaata tatataaacg ctctatatta tatttaattt aatcatggaa
    35881 acaaaaaatg attatatttt aaatgtacta tagagcgttt ttgtatcact ttaaatctaa
    35941 tcaagattca agttaatatg actgttaaat aggagccttt tcatatgatg attatttgcg
    36001 caatcccttg acaggatagg gcaaaggtgg taagctacta acagtacaaa aatactttta
    36061 attttagttc agagaggcta aaaaaggagg acgaaagatg ttaaaatcaa gaaatttaat
    36121 ccaaccagaa gacttttcaa tagaagaaat agatgaaata ttagaattag ctcaaaaaat
    36181 aattgacaat ccgtcaaaat attctcgtat atgtgaagga aaactattag ctacattatt
    36241 ttatgaacca tcaacaagaa caagattaag ctttgaatct gctatgaaca gattaggagg
    36301 acgtgtagta ggcttttcag agccaaattc atcctctgca tcaaaaggtg aaactctagg
    36361 agatacaatg aggatagtat ctggttatgt tgatataata gctatgagac atcctcaatc
    36421 aggtgcagct tcagaagcag ctagatatac ggaagtgcca tttataaatg caggagacgg
    36481 caagaaccag catccaactc aaacacttac agacttactt actataaaat cattaaaagg
    36541 aactttagaa agccatacaa taggattatg tggtgattta aaatatggaa gaactgtgca
    36601 ttctttggtt aaggctatgg caagatataa aaatacaaag tttgtattta tagcgcctga
    36661 agagttaaaa atgccagatt atataaaaga agctataaag ggacatgcat attatgaaac
    36721 taataatttg gatgatgtta taggaagctt ggatgtttta tatatgacta gagttcaaca
    36781 agaaagattt gaagataaat cagagtatga aagacttaaa aactattata ttttaaataa
    36841 agctaaatta gaaaaggcat ctaaagatat gttagtaatg catccattac caagagtaaa
    36901 tgaaatagac atagatgtag atagtgatga tagagctgta tattttaaac aagctaaata
    36961 tggaatgtat gttagaatgg ctttaataat aaaactttta ggtataaatg aagactaata
    37021 gttatcatat aatagtaaaa caaaggagat tttgggatgt ataaaattct ggaaaatata
    37081 tatataggcg aagatatgta tagaatgaaa gtaaaaggta attttgaagg taaaatggga
    37141 caattctata tgttaagagc atgggatact tatccagtac tttcaagacc tataagtata
    37201 catgatatag atgaagaagg gataactttt ctttataaag tagtaggaga aggaactcaa
    37261 attttgagta acctaaaggt aaatgataat ataaaattag aaggccctta tggtaatgga
    37321 tatgctaagg ttgatggaaa ggtagctcta gtaggaggag gaatcggtgt agctccacta
    37381 tatttggttg ctaaaaatat aaaaaattgt gatgcatatc ttgggtttag agaagatgtt
    37441 atattagaag atgaatataa acaagtatgt aataaagtct atacaacagt aggaaatact
    37501 tttgtaacag atataattga tgttgagaaa tatgattata tattaacatg tggtccaact
    37561 ccaatgatgg aaaaattagt taagatggta gaaggtacta aaacgagaat tatggtatct
    37621 cttgaaaacc atatggcttg tggagtaggt gcctgtttag tatgtacgtg taaaactaat
    37681 ggaggaaata aaaagacttg taaagatggt ccagtgttct ggggagagga cgtgattttt
    37741 aatgggtaat ttaagtgtga aatttggaag tgtagaattt aaaaatccag taataatggc
    37801 gtctggaact tttggatttg gaaaagaata taatgagatt tatgatatac aaaaacttgg
    37861 tggtataagt agcaagggtc ttactttaaa taaaaaacct ggtaacaatg gtatgagagt
    37921 tcatgagaca ccatccggta tgatgaatag tgttgggctt gaaaaccctg gagttcaagg
    37981 atttatagac tatgaattac ctttttttag taaactagac ttagtcagaa tagctaatgt
    38041 tggaggtggg acattagaag actacttatt aggggttcaa atgttaaatg acaagcctat
    38101 agacattatt gaattaaata tatcttgccc aaatgtcaaa gctggtggaa tggcttttgg
    38161 tataaaaaat gaagtggcaa gagaagttgt tcgtgaggta agaaacataa cgaaactgcc
    38221 tttagtaata aaattatcac ccaatgcaga agatattgta ggaatggcaa aagtttgtga
    38281 agaagaaggt gctgatggag tttcattagt taatactttt aaagcaatgg caattgatat
    38341 aaaaaataga agaccagtat ttgaaaatgt atatgctggg ttatctggac cagctataaa
    38401 acctatagct ttgagaatgg tacatgaagt gtgtaaaaat gtaaatatac ctgtaatggg
    38461 aatgggcgga ataactaaag ccacagatgc tatagagttt ataatggcag gagctacttg
    38521 tatccaagtt ggaactgcaa attttatgaa tcctagaata ggtattgaaa taatagatgg
    38581 aattaatgaa tttatggata gagaaggaat aaaaagttta gacgaaataa gaggaattat
    38641 ataaggtaga ataaatagta ttttaaagat aaaaaatata gattaaataa acaataattt
    38701 tataacatta acatggagga aaaataatat gagtaaagta gatgtagtgg atatattaaa
    38761 gaaaagtgat gcattgttgg agggacattt tttattatct tcaggaaaac acagtaatag
    38821 atacgtacaa tgtgcaaaag tattaagatt tccagaatat gctgctgagg tattaagtac
    38881 agttgttgaa caaataaaag acttagatat agacttagta gtaggaccag ctatgggtgg
    38941 agtaatagtt tcttatgagt taggaagaca attaggaaaa gaagctgtat ttactgagag
    39001 aaaagacaat acaatggagt taagaagagg atttgaagtt aaaaaaggag caaagataat
    39061 aattgctgaa gacgttgtaa ctactggtaa atcaactatg gagacaaaaa gagtattaga
    39121 agccttaggt ggagaagttg taggtgttgc atgtatagca gatagaacta atcatgatat
    39181 aggtatgcct atatatagtg ctataaaact tgatattcaa gtttatgaat ctgatgagtg
    39241 tcctttatgt aaggaaggaa aattaccagt tgttaagcct ggaagtaggg agttcaagga
    39301 attagggatg taataaaaac ttaattattt atagtgttac ttaaaaaatg taaatttttt
    39361 agagtaaaaa tttgtaatat aacatataac ttaaaaataa aaagcagtta gccttataaa
    39421 tgaaggttag ctgttttttt tgttaaaaat atatttacaa aataagagat agtagcagta
    39481 caatataagt ataaggtaaa agtattatat attagggagg ggtaagtatg aaaaatcaat
    39541 taaatgaaaa tcataaaaag gttgtatttt ttggagtagg tgctgtagga gctacttttg
    39601 cagaacaatt ttttaactct aaatatgatt ttaaaattct ttgtgataat gaaagaaaga
    39661 aaagatattt agaagaagga tttataataa atggaaaaag gtatgatttt gattatgtaa
    39721 ctaaagatga gtataaacaa gaggctgatt ttataattat aggtctaaaa tataataatt
    39781 taaaagaaaa tataaaagaa ttagatggat tagttggaaa aaatacagtt ataatgtctc
    39841 tgctaaatgg agttgatagc gaagagataa taggagaaag atttggaatt gaaaaaatgg
    39901 tatattcata tgttaccaat atagatgcaa agaaaatcaa taataatatt atacacacta
    39961 ctaatgggat aattgtattt ggtaacaaag ataatagtga agatagaaaa actaatataa
    40021 taaccgaagt ctttgatgat gtaaatatag aatatacttt atcaaaagat attcaacgag
    40081 atatgtggtg gaagtacatg gttaatattg gtgtaaatca aacttcagct atacttggtg
    40141 caccttatgg agtttttcag agttctgagc atttaagaga attagcaaaa tctgcaatga
    40201 gggaagttgt tgctatagca caagcaaaag acatatctct tacagaagat gatgtggaac
    40261 attcattaca tagaatacta gaacattcaa aagaaggaag aacatcaatg cttcaagatg
    40321 tggaagctca tagacttaca gaagtagata tgttttctaa gaatatctgc aaacttggaa
    40381 aaaaatataa catacctact cctataaatc agactttctt ttatatgata aaagtaattg
    40441 aaagtagatt ttaaagggtc tttgtaagaa atattgataa ttattgattt taaattttat
    40501 taatgttata tactatttaa gttactaaat atttttaact cttcaatgaa aatagttgct
    40561 gcttttgata aagttatatc ttttggaaat atatatgaga aatgtctgtt gtagctgctt
    40621 ccaagctcta tgacagacag ctcattgttt agaacaggta agcttgtcac tagattagag
    40681 actattgtaa ttcctaaatt atttctaaca gattctttga cagcataatt acttccaaaa
    40741 accatcatac tttttggaat aatttcttta acacttaaaa acatatctaa ataatctctg
    40801 gttccagaac catcctccct gactatccat ttttggtttt gaagtttatc aaaactaaaa
    40861 tcttttaata aatgactctt gtatggaagt gctaaaacca tcttatcttc aaaaaaatat
    40921 tcttgaataa atgaagggga agagcaagtg ccttcaataa gaccaatgtc taaaatataa
    40981 tccttaacat gagaagatac gattgatgta ttttttataa aaacttctac atctatgtca
    41041 ggatactttt tagaaaataa tgctagaaaa tttggtaaaa tatactctcc aatagttaaa
    41101 cttgcaccaa tctttaagtg accagttata gcatctgaaa cttggcttac atcatgataa
    41161 gtaatattta aaagatttaa tatttcttta gctcttttgt acaagatttg tccactttct
    41221 gttataaaaa tggttttttg tttaatagac ctgtttataa gcacaacttt aaaataattt
    41281 tctagatttt ttatgtgttt acttacactt ggttgtgata gatttaaata ttccccagct
    41341 ttagtaaagt ttttgtattc aacaacagct acaaatgttt ttaattcttc aaacaatttt
    41401 ttgtctcctt tacctaatga aattttacat tttttatata ctttctacag ataattatac
    41461 tatatataat aaccattaaa aacattaatc attacgatat tatatattta ttttacttat
    41521 ggttattaca attatatact attgctatga agaaaactat attaattata aggtaggtat
    41581 attatgttaa agaaaaaaag cagtttgaca ttaaaaacta taagggaaat attaccagga
    41641 ctgtttgtat cagtattagt aggttatatt agtatattta tttctatttt aattcctaag
    41701 gtaggggcag catcaatttc tatattttta ggtatgtttg taggaaacct atttttaaat
    41761 caaaaggtat ttcaaaaagg ttataaattt tcagagacag atttgttatc atattcaata
    41821 gtactattag gagcaacact cagtgtatct actttaatag acttaaaagt ttcaggaatt
    41881 ttatttataa tattgcaaat gacaataaca ataatagctg cactttatat aggtaaaaaa
    41941 ctaggatttg aagaaaactt tagatttcta atggcaagtg gaaatgcagt atgtggttct
    42001 tctgcaatag gagcaacagt tccagtggtt aatgcgacag ataaagaaaa gggaattgca
    42061 gtaactattg taaatgttac tggtatattt cttatgtttt tacttccaat aatatctcaa
    42121 tttttatata gccatgaact tgtaaaaact tcagcaatga taggtggaac tttgcaatca
    42181 attggtcagg ttgtagcaag tggagcaatt gttggagaaa atgtaaaaga tttagctact
    42241 atttttaaga tagtaagagt aatatttcta gttgttgttg tattagtatt tggacatatg
    42301 aaaaatcaat ctaataggga aattcttgaa gaagaaaagg atgagataaa aaagaaaaaa
    42361 gtgactatac catggtatgt aattggattc tttataactt gtgcactttt ttcaatgaac
    42421 attataccaa aagaagtatc tgtgttgtgc aaagaaataa gtaacaaact agaaataata
    42481 gctttagcag caattggatt aaaggttaat gtaaaagatt tagtgaaaca agggaaagaa
    42541 gtttctttat atggtttatt tgtaggtaca gtacaagttg tatcagctgt agttttaata
    42601 aaaatattta tatagtataa aaatagtatt tgtaatacta atttgattaa ttaaaataat
    42661 atgatactaa taatttataa tataaataaa aaatgaattt cgataagttt aagtgggtat
    42721 aaacttatag aaattcattt tttatttaag gtaaaaattt aaagtaaaat attattttac
    42781 ataataataa ccttataaat tttgaaatta cttatctttg tgttaaaata agtaaaatgc
    42841 acatattaga gctaagtttt taagtaaata aacaaaatga aaatataaat attaaggaga
    42901 tttggtatat gaatgtttat gaaaaaggta atggagttat actagaaaga gtaacagatt
    42961 ttgacccagt acatatattt gagtgtggtc aatgttttag atggcacaaa caagaagatg
    43021 gctcatacac tggagttgca aaggggagaa tattaaatgt caaaaaagag aatgataaaa
    43081 tatatttaaa taatactaat ttaaaggagt ttaacagcat ttggtataat tactttgatt
    43141 taggaactga ttatacagaa ataaagaata agctaaaaaa tatggatgaa tatttaaata
    43201 aggctactga atttggatgg ggaataagaa tattaagaca agatggatgg gaaatgctta
    43261 tatcatttat aatttcctct aataatagga ttcctatgat acaaagagcg atagaaaatt
    43321 tatcaagaaa gtttggtaag tatataggtg aatatgaagg taatgaatac tatgcattcc
    43381 caacaccaga agaactaaat aaggcctcac aagaggaaat aagagcatgt caaacaggtt
    43441 ttagagataa gtacataaaa agtactacac aggcagttat agagaataat gatgaggtat
    43501 ctgaatatac aaatttaagt acagaggatt gtagaaaaga gcttttaaaa tttaatggag
    43561 taggaccaaa agtatgtgat tgtattgcat tatttggtat gcaaaaatat gattcttttc
    43621 cagttgatgt ttgggttaag agagttatgc aagaatttta tatagatgaa gacatgagtt
    43681 tacctaaaat gagaacttat ggaatcgata aatttaaaga aatgtctgga tttgctcaac
    43741 agtacttatt ttactatgca agagaactcg gtataggaaa ataaattaag ggggagaaat
    43801 tatgggagta ataggaacaa tatttctgtt ctatttaatt atatcatatc tagctggagc
    43861 cataatttct gtgattatat tacttgaaaa tagagaccct gcaaaaacaa tgtcttggct
    43921 attgatgttt attatatttc caggtgtagg tttaatgata tatgctattt caggtagaaa
    43981 tattagaaaa agaaaattat ttaagactca aaaactagct aataatataa aagaaaagaa
    44041 actatttgat acattagaaa agataacaga aatagttgaa ttagaaaaag aatctataaa
    44101 acaaaataag cttttaagag atgaagagga tggtagttat agaaaaaggg taataaatat
    44161 gttgttaaag actggtatgt ttccctttac taaaaataat aaagtggatg tatttgtaga
    44221 tggaaatgaa aagtttaaaa gacttataga agatataaga gaagctaaag accatattca
    44281 tttagagtac tttatcatca aagatagtga aataggtagg gtgttaaaag aagaacttat
    44341 aaaaaaggct aaagaaggca ttaagataag aattttatat gatgatgtag gatgctggag
    44401 attttggttt aatagaaaat ttttccgaga aatgagggaa gtaggtatag aaattgcagc
    44461 atttttacct acaaaatttc ctataatagg agggaaatta aactatagaa atcacagaaa
    44521 aattgttgtt attgatggaa taattggata tacaggtgga ataaatatag gagatgaata
    44581 tttaggcaaa aatgataagt ttggatattg gagagatact catattagga ttaagggtat
    44641 ttctgtatac atgcttcaaa tgacatttct gattgattgg tattatacaa caaaagaagt
    44701 attagtgact aaaaattatt tcccaagtgt agggaatgtt ggtgaaagta tgatacaagt
    44761 tgttgcgagt ggtccagaca gtgactggga agatattcat tatgcttatt tttctgcaat
    44821 atgtcaggct agaaaaaatg tttatataga aactccatat tttattccag atgaaagtct
    44881 actaaaagct ataaagagtg ctgctcttag tggagttgat gtgagaataa tatttcctaa
    44941 aattgcagac cacaagatag taaatatagc atcttattca tattttgaag aaatattaag
    45001 agcaggtggt aaagtttatt tatataataa aggatttata cattctaaag tcgtaataat
    45061 agatgataaa attgcttctg caggtacagc taatatggat ttaagaagtt ttatgcttaa
    45121 ctttgaggta aatgcattta tctatgatga agaagttatt agggtaatga cagatgattt
    45181 ctttgaggat ttaagtcact gtgaagaact taatttggag gtatttaaga atagaaatat
    45241 catacaaaaa atcaaagaat ctgtagcaag attattttca ccaatattat aaaaaattat
    45301 taaaaaaggt attgaaaatt atgtgtgatt ggtatattat aataattgtt agcactctat
    45361 tagatagagt gataataaat aaaaagtata tatataaatc tacatatata agtagtatta
    45421 atttaaaaat aactaaaaac ataggcgaac tagtctatac ttaatatttt aggaggcgtt
    45481 aataatgaaa ataagaccat tagctgacag agtagtaatt aaaaaagtag aagcagaaga
    45541 aaaaactgca agtggaatag ttttaccagg agcagctaaa gagcaacctc aaatagctga
    45601 agttgtagaa gttggaccag gtggaatagt tgaagggaaa gaaataaaaa tggaattgac
    45661 agtgggagat aaggttatat tccaaaaata ttctggaaca gaagttaaga tagaaggaca
    45721 agaatacaca atactaagac agagtgatgt attagctgtt attgaataaa tatagaataa
    45781 atttattagg aggggtttaa aatggctaaa gaaattaaat tttcagagga aacaagaaga
    45841 gctttagaag ctggtgtaaa taaattagca gatacagtaa aagtaacatt aggacctaaa
    45901 ggaagaaatg ttatattaga taaaaaattt ggttctccac ttataactaa tgatggagta
    45961 actatagcaa aagagataga actagaagat agatttgaaa atatgggtgc tcaattagtt
    46021 aaagaagtag caactaaaac taatgatgta gctggagatg gtactacaac tgctacagtt
    46081 ttagcacaag ctataataag agaaggttta aagaatgtaa cagcaggggc taacccaata
    46141 cttttaagaa aaggaataca aaaagcagta acagtagcag tagaagaatt aaaaaatcaa
    46201 tcaagaatag tagaaacaca agaggctata tctcaagttg cttctatatc tgctggtgat
    46261 gaagaagttg gaaaattaat agcagaagct atggaaatag taggtaaaga tggagttata
    46321 actgttgaag agtctcaaac tatgaatact gaattagatg ctgttgaagg tatgcagttt
    46381 gatagaggat ttgtttctgc atatatggtt acagatgtag ataaaatgga agcagtttta
    46441 aatgacccat atatattaat tactgataaa aaaatatcta acatacaaga attattacca
    46501 gttcttgaac aaatagttca acaaggtaaa aagttattga taatagctga agatgtagaa
    46561 ggtgaagcat tatctacatt agtagtaaat aaattaagag gaacatttga tgtagtagca
    46621 gttaaagctc caggctttgg agatagaaga aaagaaatgc ttcaagatat agcaatactt
    46681 acaggtgctc aagtaatatc agaagaatta ggttatgatt taaaagaagc tgatttatct
    46741 atgctaggta gagcttcatc tgttaaggta actaaagaaa gtactacaat agtagatggt
    46801 tctggagata aaaaagctat agaagataga gtaactcaaa ttaaacatca agtagagcaa
    46861 actacttcag attttgatag agagaaatta atggaaagat tagctaaact tgctggagga
    46921 gtagctgttg taaaagttgg agctgctaca gaagtagagt taaaagaaag aaagttaaga
    46981 atagaagatg ctcttaatgc aactagagca gctgtagaag aaggaatagt agctggtgga
    47041 ggaactgctt ttgttagtgt tataccagca ataggaacac taattgagag tttagaagga
    47101 gaagttaaac taggtgctca aatagttaaa aaagcgttag aagagccatt aagacaaata
    47161 gctataaatg ctggtcttga aggtgctgta attgtgcaaa atgttgttaa ttctgaagca
    47221 gaaactggat ttgacgcatt gaatgaaaaa tatgtaaata tgatagaagc tggtatagtt
    47281 gacccaacta aagttagtag aagtgcttta caaaatgctg catcaatagc aagtactttc
    47341 ttaactactg aagctgctgt tgctgacctt cctgaaaaag aagatgcagg aatgccagga
    47401 atgggtggcg gaatgcctgg tatgatgtaa tttaaaaaat ttaaaatata aattttaata
    47461 taaagaacta tttcgactta gattttaaac tctaagttga aatagttctt ttgtatatat
    47521 ctaatttttg tatatctata aattcaatac acatatttag ataatcagta tctagtttgt
    47581 aataatattt tagagtagta ttgttatttt ttaggttatg attttagata tatattaatt
    47641 aaggtataat tgttgataga gaataaatca aatttaaaag gatgcgataa tatggactta
    47701 agaaaattgc ttgaagaagt taaaaatgaa aatattgata tagattttgc gttagaaaag
    47761 ttaaaagatt taccttatga agaccttgga tatgcaaata tagaccatca tagagaatta
    47821 agaaatgggt atccggaagt tatttattgt gaaggtaaga gtgatgagca tattttaggg
    47881 attattgata aaatgaatca aaaaagttct aacatattgg ggacaaggtg cagaaaagaa
    47941 acttttctga aaattaaaga aatctataat catgctgagt atgaagaggt gtctaaaatt
    48001 cttaagattc aaaatcatga tatagagaat ataggaaaag gtaaaattgt gattgctaca
    48061 gggggaactt ctgatatacc agtagcagac gaagcttatc atacagctaa gtttttaggt
    48121 aatgatgttg atagaatata tgatgttgga gtggcaggta tacataggct tttaaataaa
    48181 agacataaaa tagatagtgc tagagtaata gtagccgttg caggtatgga aggtgctctt
    48241 gcaagtgtaa ttggtggact ggttgatgtt ccagtaatag ctgttccaac ttctgttgga
    48301 tatggagcaa attttggagg attagcagca ttactagcta tgttaaatag ctgtgcatct
    48361 ggaatatctg ttgtaaatat tgataatgga tttggagcag gatatttagc atcaatgata
    48421 aataaactgt aaatacattg atataaatta aacaaaacta tataataaaa tttaatttct
    48481 attatatttt tactattaaa attgaggaga catatatgag tgaaaaaata ctttattttg
    48541 atataataag cggtatatca ggggatatga cccttgcaag tttattaaat ttaggtgtgc
    48601 ctaaggaaat ttttttggag gaaattcata aactaagaat gagcgatgaa tttaatataa
    48661 acatcagctc gaaaactgaa aatggaatag taggtacaaa agtagaagta attacaaaag
    48721 aaaaacatac gcatagaaat ttagtggata tatttgaggt tatagataaa agcactctaa
    48781 acgaaaatgt aaaatttaaa gcaaaaaaaa tatttatggt aattggagaa gcagaagcaa
    48841 aagttcatgg aactacaata gacaagatac attttcatga ggtaggggct atagattcaa
    48901 ttgtagatat agtaggagct tctatattag ttgacttact ttgtgtagat aaagtttgtg
    48961 ctagtacagt gtctgttggt tcaggatttg taaaatgtga acatggaatt atacctatac
    49021 ctgcacctgc aactatagaa attttaaaag gtgtgccaat taaattaaat aatgtaaatg
    49081 gagaatgtac aactccaaca ggagctgcaa tcataaaagt cttgtgtgat gagtttgtag
    49141 atgagcttga attttctcca aagcaaattg gatatggtat aggtcataag aagtttgaag
    49201 taccaaatat actcagaact gtattaggtg aaaaaaaaaa gaagaattaa tttatgaaat
    49261 tagtgcaaac attgatgata tgtcttcaga aatctattct tatttgtatg aaaaaatatt
    49321 agatgagaaa gcattagata tttatacaga gagcatttat atgaagaaga atagaccagc
    49381 aacaaaagta tcaattttat gtaatgaatc agatttagaa aaatttatta aaatattact
    49441 tttagaaact agtacttttg gagtgagata taatgcatat aatagagaaa ttctagagag
    49501 aaaatttgta aaattagata caaaatatgg agtggttaca gtaaaactag ggtattataa
    49561 aggaaaacta gtcaaggcta ctccagaata taatgaatgt aaaactatag caaaaaatga
    49621 agatattcct ataaaaaaag tgtttgctga tataaatttt agaataaaag aagaatttag
    49681 tgaaaactta ttgacataag taataaattt tgataaatta atattcagcc ttattaaata
    49741 aaagtaaaca gaaaaaaata tataaaatat aaactcactc gtatatgctc agaaatatgg
    49801 tctgagagtc tctaccaaga taccgtaaat atcttgacta tgagtgaaat tattatacca
    49861 aaagacctag ttaagtaaat gtgtaggctg agttaaactc cctatgtgtt ggctataaga
    49921 taaaggtatt ttggaagcct gtatagtaat ttcacttttg ctagaaatta tggaagttac
    49981 tatacaggtt ttttgtgtaa aaagatttaa tataatttag actgtattgt gttaaaataa
    50041 atatataaaa actatattat acaaggagag atgtaaattt atgaaacatg aattagtact
    50101 tgtaatagat tttggaggac aatataatca gttgatagct agaagagtta gagaaaacaa
    50161 cgtatattgt gaaatacttc catgtactgc aagcatagaa agaataaaag aaaaaaatcc
    50221 taaagggata atatttacag gcggtccaaa tagtgcgtat ttagaagatt ctccaacaat
    50281 atcaaaagaa atatttgaac taggagtacc aatacttgga atatgctatg gtattcaaat
    50341 aatgtctcat gtattgggtg gagttgtaag aaaaggtaat aaacaagaaa aagaatatgg
    50401 aaaaacagct ataacttatg gaaaatcatc attatttgaa ggaataacta caaatagtgt
    50461 atggatgagt catacagatt taatagaaaa agttccagaa ggatttacta tagttgcaaa
    50521 tactaatgat tgtccagtag cagctatgga aaatgtagaa cgaaacctat atggagttca
    50581 attccatcca gaggtagaac actgtttgga aggggacaag atacttacaa acttcttata
    50641 taatatttgt aaagtaaaag gtgactggac tacagattca ttcatagaag ataaaataaa
    50701 agaattaaaa gaaaaaatag gcgataaaaa agctttatgt gctttaagtg gaggagttga
    50761 ttcttctgtt gctgcagttc ttattcataa agcaattggg gacaacttaa cttgtatatt
    50821 tgttgaccat ggtttactta gaaaaaatga aggaaatgat gtagaaagaa tatttagaga
    50881 gaaatttgat ataaatttaa taagagttaa tgcagaagat agattcttat ctaaattaaa
    50941 aggagtttct gaaccagaag ctaagagaaa aataataggt gaagaattta taagagtatt
    51001 tgaagaagaa tcaaataaat taggaaaaat ggatttctta gtacaaggaa caatctatcc
    51061 agatgttata gaaagtggac atggaaatgc tgctactata aagtctcatc ataatgttgg
    51121 tggaatccca gaagatgtag acttccaaga aattgtagaa ccattaagag agttatttaa
    51181 ggatgaagtt agaaaaatag gattagagct tggtatagaa gaaggattaa tatttagaca
    51241 tcctttccca ggaccaggtc taggaataag agttataggt gatgtaacta aagaaaaatg
    51301 tgatatatta agagaagctg atgctgttta tatggacgag cttagaaaag caggtttata
    51361 cagagaaata tggcaagctt ttgcaacatt accagatgtt aagactgttg gagttatggg
    51421 tgatgaaaga acatatgctt atttagttgg tttaagagca gttacttctt ctgatggaat
    51481 gacttctgac tggtataaga tgccttatga tgtattagaa agaatttcta atagaataat
    51541 aaatgaagtt gatggagtaa atagagtagt ttatgatata acttctaagc ctcctggaac
    51601 tattgaatgg gaataaaata tagaatgcca aaaatccaca taaatacagg atttgaggtc
    51661 tatcttactt ctatgttata ctggtttgat actatcaata tttgccagta tcttatggat
    51721 taataagtaa aaaacatcct gctgaatgat aaattcagcg gggtgttttt attttgtttt
    51781 agaactcctt tgctctgaaa ctcgaagtat ttaacactga tgattttgtt atcttttagt
    51841 tccttttgtg tcatgctctg aaagacaaat tgatacaata aaaaagtaat ttcttaatca
    51901 ttgatggaga tatgtattta tgttactctt gatggtaatt tgagtaatat tgttcatagc
    51961 tttttatatt cacttaatta gaaaaccatt tggtataatc ataaataaac ttgatgatat
    52021 aatagaaaag atttatactt attagaagta tataaaagta ttttatgtct atgaaatgta
    52081 tgtctataaa acatatagat gacttttgta tattaatgta tgaatattga tattatagaa
    52141 gaattgagtt gtcaatgata ctaaatcaaa tatttataga agctggaggg attatgagaa
    52201 ataaaataat tataggaatt actttttcac ttgtattact aatgtctgga tgtgcttcaa
    52261 aacaaaccgc agaaataaac gtattagcaa ctactgattt acatggagtt ataccttatg
    52321 agttaacttc ttatgtaaaa gaagaaagaa aaaaagataa aaatctaact ttagtagatg
    52381 caggagattt ttttgatagt ggagaagtgt ttggttctag catggatagt tattttagtg
    52441 ctagatataa agatggtgat aataacactg aaagttatat tgagacgcct atttcaaaag
    52501 atatgaaaga ggtaggttat gatgttgcag ttcttgggaa tcatgaattt atatccaaca
    52561 ataaatttta tctagataat atgatatctg attttgagaa gcaaaaaata aatattttat
    52621 cggcaaatac gtataaaaaa aatggagaca gttatacaaa accatacata ataaaaaata
    52681 ttaatacacc tgaaggaaac gtaaaactag gaattttagg gcttactata aaagaagttg
    52741 gtgagaggaa acagtggaaa gatggaaaac ttgttgactc taagtcttta gaactaaaag
    52801 accaagaggg ctacaatggt gaattgtata tgaatgattt agtagaagat gctaaaaagt
    52861 gggttagtat aatggaaaaa gagaagcctg acattatagt tgctgtggca catacaggtg
    52921 agaaacctaa gaaacctaga aacccaggaa atagaataca agacttagct caacaagttg
    52981 atggaattga tgctatagtt gcaggtcata atcatgttca aattgagcaa catgattata
    53041 aaaataaatc aggagaaaat gttatagtta ctgagccagg aaagcatgga gaatgtattt
    53101 ctaagattaa ttttaaatta gaaaaaaaca atgataaatg gaatatagtt gacaaatcta
    53161 gtaaattaat taaatttgaa aaaaatcaag aaagtgataa atttggagaa tttatttctt
    53221 caattaataa agtaagtaaa gataagaaag aaataagatt atcagaagta aagactcctg
    53281 aatgggataa aatatatgtt tttaaatctg gaacatctgc agatgatata tataaaacga
    53341 taggatataa atggagaaat atatcatctc caaagggtga tgacatggtg cagattgttg
    53401 taatgaataa taataagcct gttagctatg tatatggtga agctgaagtt atgccaatta
    53461 atataaaatg tgatgaatca gagtataaag ataatgttgt aactatttat cctaataaaa
    53521 atgataaatt taaaattgaa aaaggtaaac aagaatatag tattaattta aaacatatac
    53581 aatagaaact tttatcttat ttaagtttag attgtactta aaataaagtg tgtattattt
    53641 taaaaattga tgataattaa aatcacaaca ttaaggaata gtacacactt tttatgctaa
    53701 aaaatagaat gttaaaaaat taaaccttta aattaaagta cattgcttat attatccaat
    53761 attattttca aaggttgtgt aatattttta tctttatgta atattgctaa cattttattt
    53821 tccatatcta tcccatctaa ttcaatcaat cgcaattttt tatgtaagag tgaatctaat
    53881 aataaatttt ctggcaaaat ggttatacct aaccctgctt ctgcagcttt aataagtgca
    53941 aaagaattaa cactttccca aacaggataa gctttttggt ttgaaagaga taatacactg
    54001 tccaaagtat cgcgaatggc acttccttgc tcacgtaaca ataacggaaa cgtgcataac
    54061 tgtcgtagag ataaggcttg tttagataaa ggaaaagttg gagcacatgc aacacataac
    54121 ttataggaac ctaataaaat tgtacggaat gccccctgtg gttctatacc ttcccaaaag
    54181 catatatcag cttctccact ttttaaaata tccatagctg aattagcact ttcgacacgt
    54241 acattcactt taagagatgg gaatgaattt tttagtcgac ttaaaattgg tggaagtaaa
    54301 aaagaggcaa ttgtaatgct agaaacaatg tttataggtg tacattcctc taaatgactg
    54361 attcttttgt ctaaattacg acaagcagtt aagatactac gtgcttcttc taaaagagaa
    54421 atgccacagc gagtaagaca tacccctcgt ggtagtctgt caaataatgc tgtttcagct
    54481 tgttgttcaa gttcagctat agcatgagat acagcagatt gtgtgatatg taattttttt
    54541 gcagcacctg taaaagtgcc tgtttgttca attgcttcta aaatctctaa atatcgtatg
    54601 tttatcataa taaatatcct cactagacat gaataaaatt gattaattcc attaaattct
    54661 atcattttac agattgcaaa gcaacaggta tactgaataa tatgaagtga aaagaaggag
    54721 gaatattttg aatcaaagca gaaaaacata tttttggctt ttaattatta acttgtttat
    54781 tagcacattc acttttggtg gagggtatgt agttgtacct atgattagac gttattttgt
    54841 aaatcaaaag caattcttta cagaagatga tttgatgagc atggcagcag ttgcacaatc
    54901 aactcctgga gctattgcaa ttaatttatc tgctttggca ggttatcgag tagctggtac
    54961 tttaggggtt gtcattagtt gtatagcagc tataatacct ccgctcgtta ttcttggatt
    55021 agtatcagca ttttacacca cttttatatc taatgccatt gtaattgcag tattaaaagg
    55081 aatgcaagct ggtgttgctg cactaattgt ggatttgatt attgacatgt gctctatgat
    55141 attaaaacaa cgttctctat ttttatcagc tatgatacct attgctttct ttgcaaactt
    55201 tgtgatgagt ataaatgtaa tttttatatt atctgtttgc tgttttgtat gtgtaatgca
    55261 agttttctac aagaagaggg aaaataaatg aatacaattt ggaatttatt ttttatattt
    55321 ttaaaaatag gcttgtttag tattggtggt ggttatgcaa tcataccttt aatccaagag
    55381 aaagtagtaa atcaaactgg atggataagt gagaaaatgt ttacagatat tataactatt
    55441 tcacaaatga caccagggcc actggctgtt aatacttcta cttttgttgg acttcaaatt
    55501 ggagggtttt ggggagcagt tgcagccact ttaggttgtg tattatgtgg tgtagtaata
    55561 tctctatttt tatataattt ttttcaaaag catcagaact ctacttatat atttgaaata
    55621 ttaaatggtc taaaatcagc ttcattaggt ttaattatct cagctgcggc tacaattata
    55681 atccttgcat tatttgggac gaataaagtg tacttcaatt ctatatttga gatgctaaac
    55741 tggactgcac taataatctt ttttgttaca ctactgatag tacgtaagtg gaaaattaat
    55801 cctattgtga ttataataat aagtggtata ctgggaatat ttttttattt ataagttttt
    55861 gctaagtaaa ggatatctat ttttttatat cttaaatcca aatagccaat aaagtaaggc
    55921 tatttggatt tttaataaat tctgaaaaga taatcagaaa cccatataac atttaaatta
    55981 tatcactggt tttctacaaa ccaatcataa gcttcttggc aaaatttctc actatctata
    56041 tagtaactat tatgaacatt attaatttca acaagtttct ttttacattt tagtgaatta
    56101 taatagctat caaaatattg ggttttaaaa tatctatcat gaagtgtttt aaagacaaga
    56161 gtaggtatgt tgactccatc ttttatctta ctatcttctg caataaagca ttctaacatt
    56221 gtattaatta tctttgtact atttttccaa atatgaggat ttttcttttc aaatatttta
    56281 taaaattcat tatcatagac ttcattataa cctttatatt taggtggttt tactgttatg
    56341 tgaaaattag gaagaaactt aaagaaaaaa tataataatt tttatgttct gttttatata
    56401 ttattcatat tttatcacag ataatatact aaagttaatt tttttattgt acaactatta
    56461 taataattct tctataatat aagacattct ataattttat atttaagttc atgtgtattt
    56521 aattgttttt atataaaatg tccagtaata ctatttggat ttatttttat ttcatcagga
    56581 gttccagaag caacaatttc ccctccattt attccactgt ctggacctat atcgataatc
    56641 caatcagaag cacgtataac ctctgtattg tgttcaataa ttaaaagtga atgctgttca
    56701 tttacaagtt ttctaaaagt aattaacaaa ttttctatat ctttaaaatg aagtccagta
    56761 gtaggctcat ccaatatgta cagcattcgt tttttagttt ttgtccctaa ttcttttgct
    56821 aattttatcc tttgagattc tcctccactt aatcctaatg tattttgtcc aagctttaga
    56881 tatccaagtc ccacttcatc taataaggag agttttctat atatatcaga gcaatcgcta
    56941 aaaaatgttt ttgcttctgc tacttccatg tcaagtatat ctgcaattgt ctttcccttg
    57001 tattgtatag acagtatttc tttttgatat ctcttacctt gacatttact acaagttacc
    57061 cattggtctg ccatatattg cagaataatt tttgttttac ctaatccttg acagtttggg
    57121 cattgcccct ttttgctatt aaagctaaaa tagctttcat ccaataattt ttgttttgct
    57181 tgtggagttt cagcaaatag agaacgaatt tcatcaaaaa tattgatata tgtagcaggt
    57241 gtagaacggc tagattttcc aataggtgtt tggtccatta agataaaatc atcaatagca
    57301 tcaaatccag taaattcagt ataattttta tctgggatag atttttgttt caatttttct
    57361 tctagagcag gaagtaaact gtgaaataca agagagctct taccagaacc actaacacct
    57421 gtaatagagc acatacagtt taagggaatt tctacatcaa tattttttaa gttatttgca
    57481 tggcatcctt ttaagcttaa ccatttactt gggataattt tattttgtga acctgtttta
    57541 ttgtatgtac ttaaatattt acctgttata gagtttggat tttttataat ttcttgggtt
    57601 gtaccttctg caataatgaa cccccctttt gtaccagcac ttgggcctac atcaataata
    57661 taatcagcag acagtattgt atctttatcg tgttccacaa ctataacagt attaccctta
    57721 tctcttagct cttctatcat tttgatgatt aaattatggt ctcttgggtg taaaccaata
    57781 gatggttcat ctaaaatgta ggttaagcct actaattcac ttcctagctg acttgataat
    57841 cgtactctct gcagttctcc tccagataaa gttggagctg ttctatctgt tgatatatag
    57901 ctaagaccta cctttaatag ataactaact cgaattttta attctgttaa gatatcattt
    57961 accaaagaga gctcattttt ttgaagttga tttggtaatt cacacaacca attccataac
    58021 tgttctatcg tcatttttgt tagttcaggg aagcgataac ctttgattgt agtgaatcta
    58081 gcctcaatgc acagcaattc gccaccacat gtattgcaag gaattttgtt catatattga
    58141 tgcaaggtat tattttcaga actagattct ctaaaaagtc tttgaatgtg gttgattgct
    58201 cctgaagcag gtcttctaat ctttgattct cgtccctttg attcaaagct aaattcatat
    58261 atcttatcgt ctgtaccata taagattgca tctataaaat ctcttggtaa ttcattccaa
    58321 ggtatatcta ggtctatatt tttatctttt gctattgcat ataattcacc taccatccaa
    58381 ttaccatttg gctttttccc cctcaatttt ccaaaatagt aagtggctcc atctaatatt
    58441 gaaatagttg ggtcttttac aatcaattga ggattaactt gataggtaaa acctaatcca
    58501 ttacaatcgt gacaagctcc agtatgggag ttagcattga aggttgaagt atttatctta
    58561 gaaaaaatag tttgacaatg tggacaataa ttttttgtat tattcttttt ttctaatgga
    58621 attttgcaat atggacagta actttttccg attgatacaa ataacattct taaataatcc
    58681 caaatgcttg taagagtacc aacagtagag cgaggatttt ggcttccttt tttctgttcg
    58741 atagctatag taggggttaa tccctgaagt aaatcaaatt ccggtttttg aagctgttct
    58801 gaaagttttg ctccattact tagattttca aaataacgtc tttttccttc ttcataaatc
    58861 gtatcgaaag ctaaagaaga ttttccacta ccacttacac ctgtaataac agttatttga
    58921 ttttttggaa ttgtaacctc aacatccttt aaattgtttt gccttcctcc ttttaaatag
    58981 atagagcttt tattatgaca aagtgaattt ttaattgatt tatttattga ttttgtaaat
    59041 ttgaatttct tttcgagttc aagaggattg cctaattctt ttatttccga aatgcctaat
    59101 atttttaact gagaaaagat tgatttcaaa taatcttcag gcagtttttc tattaacaaa
    59161 ttaaggtctt ctatttttat atttccgatt gataatattt ctgccatttc atctaataaa
    59221 tttttttctg ctcttgttaa ttgattgtat tttttggaac ttaattctgt ccataaatcc
    59281 catggaagca attctaaacc aatcatatta ttaaagtcat gtagaagatt accctttaca
    59341 gaatgccaac ctttccaatt tttattatat ccaaagtcat ctggatgagc atgtccttgc
    59401 cgacatctta tccaggcttc tgaaccagtt aaaaaaccat ctgtttttcc gacatcatga
    59461 gtgtcaaaat taatttgaaa ataatttttt tgtatgtcat ctatttgtgc atctattctt
    59521 atccatctct ttgttagagt atcatagtat tctacaagcc agtggtcttc ataagtaagc
    59581 tcactttcaa aataattagc aaaacctgct ctcattctag cctcaaaacc tcgatatctt
    59641 aggagcgata caagaagtaa agaataatct ctgcacattc caacaagcct ttgttttggg
    59701 tttcttggaa tagttagtgg gttagaattt atttcaaata ttctttttaa catttgagga
    59761 attgtacgaa gcaattcctc atcagattgt tgtttattaa aggatatacc atataatttt
    59821 ccttggtctc catgaattac taggctttga accactttta ataactcaat tggagtcttt
    59881 ggtaaatctt gatatttatt ttcaaatttt ttaggatttg tgatgatact ttgattttta
    59941 tagttattta ttttcattta tatttcacct ctctaaatgg atgatatacc ctgacatggt
    60001 gtcatatgca aggacaattt agattttttg gccaaaattt aaaaataaat aaaaaatgat
    60061 acagtgataa attgtaatac aaatatagtt tcaaattgca tataatataa ttatttaata
    60121 aaaccattat ctattgaatg ttaatgaaat gttaagatgg cattcttgaa tattaagaaa
    60181 tagaatacta taatatagtg tgaaggattt ttagtaaaaa aatttgtaag tgttaatata
    60241 cattaaaaaa taggtttata atttggagga aaaaaatgaa attatcaagg tataagaaaa
    60301 atagtttagt tctgtctata attttatgtt cacttattat ttcaatcctt gtaattactg
    60361 tttttaatac cgtaaaacta cacaatatat ctaataaaca atctaaaaac tatttaaatg
    60421 atgtatctac acagattgta atgaatgttg attctaaaat caaatttatt ttatccgact
    60481 taagaataat ggcagatttt attaagcaat atgaaggtga tagtcgatat gagtatttat
    60541 ctaaaagaaa gactagttat aagtattatg atgttggaat aatagattta gaaggtaaag
    60601 ctgagttttt aagtggaaaa aagtttgact taaagaatac tgtttcctat aaaaaaggaa
    60661 ttgaaggtaa agaatactca gaagtaatag agtcaatggg ttttgttctt tatagtgtac
    60721 ctatatttaa tgataatcat gaagtatcta gtattttaat aggtgtatcc aataaagaaa
    60781 gtatgaatga gattcttaat atagataact ttaatggaaa aggaactatt gaaattatta
    60841 atagtaaggg aaaacctctt ttcataggaa aaaatactga attaataaag gaccttagcc
    60901 ataaatataa gagttctgga gatgaacctt gggcacaaaa gatgcttgag gattttaaaa
    60961 atgataaatc agggaatatt acaataacct catcaaaagg tgtacaatgc ttattaactt
    61021 atcatccaat tacaagaggt ttaaatgatt ggcattttct tctcatagta cctgaagatg
    61081 ctgtacttgg tgaacttaat aaattaaact cttttacaat aacaatgaca tttataatta
    61141 catgtattat tggaattata acattaattt tatatattat aagaagaaaa tatgtaaatc
    61201 aaatagaaaa tattgcatat ttagatagta taacaaatgg tataaattca actaagttta
    61261 gtatgctagt caaaccttta atttcagaat cacctgatag tacttatatg atgatagcaa
    61321 tgaatataaa agattttaag ctaataaatg attgtttcgg tagtgaaaag ggaaatatga
    61381 cactaaaaca tctttacaat attttgtata aaaacattga tgaaaatgaa gagtttgtgt
    61441 gccgtcatga tgcagacctt ttctatttgc ttattaagaa tagaccagtg ttagaagccc
    61501 tggagttatt atataaaata gaagctgaca caaattattt taataaaaat agggaaaatc
    61561 catacttttt aagactatca gtaggtattt acacaattga aaatcataat gaagatttaa
    61621 ttacaataca agaccatgca aatacagcaa gaaaaagctt taataaaact catcaaagtg
    61681 atttttcttt ttatagtgat atagaaagaa aacgattaat atctgaaaag gaaatttcaa
    61741 atttaatgga aaaagccctt gaaaataaag aattttttat gtgcttacaa cctaaaattg
    61801 atataaaaag tggaaaaatt agtggagcag agtctcttgt gcgttggaaa aattcagaaa
    61861 agggcataat ttatccaagt gattttattc ctcttttcga aaaaagtgga tttatatgta
    61921 agttagattt atatatacta gaagaaacat gcaaattgat ttctaagtgg ataaaagaag
    61981 gtaaagaagt gttgagaatt tctgttaatg tatcacgtca acatctgaat gataaattgt
    62041 ttttagaaaa atataagcat atatgcaata aatacaatgt accaacatgt ctgatagatt
    62101 tagaacttac tgaatctatt ttcttagaaa atccagaagc tatagatata atagaggata
    62161 ttcattctaa tggatttaaa tgttctatag acgattttgg atttgggtac tcatcattag
    62221 ggatattaaa ggattttaaa gttgatataa ttaagttaga ccgttcattc tttgttagca
    62281 aaaataatat agaccgtggt aaggtagtta ttaagtctat tattgaactt agcaaaaggc
    62341 taggtatgaa agtaactgct gaaggaattg aagaattaga acaagttgag ttcctaaaaa
    62401 atgtgggatg tgattatatt caaggttatg ttttttcaaa accattatta atttctgact
    62461 ttgaaaattt tgcatatgaa aataataaaa ttaaaaatat ccattattaa atgtacaaga
    62521 taaaaaattt aggcaagtta tataattaaa aatataactt gcctttttta tttatatatt
    62581 taataaaaat atatttgcag attttgtaaa aataattttc aaatgttgta agttgtggct
    62641 aaagctttat tgtattattc tgaatataga aagatagtta ctgtcttaga taaaaactga
    62701 aacatacata ataatataaa atttgctata ttaataactc taattatttt ggaaggaggg
    62761 aaaatatgat aagtgggaga atgttactca tcatgaattt tctaaaagga aaaaataaga
    62821 caagttacaa ggatattagc aaacaactta gtatagaaga aagaaaagtt agatatgata
    62881 taaataattt aaatattgtt ttgcgttcat taaacaagtc agtaatacaa aagatgaaca
    62941 aaggtgtgtt aattattcct gatgacttcc aagtagtatg tataaataat aacgaatatg
    63001 tattttcctt aactgagcga gtatctatta tgaaaattat atcaatgttt aaaatagata
    63061 atctaaactt agaaaaatta agtaaagaat ttcaggtttc tagaagttca attaaaaatg
    63121 accttaatgt tttgtcaagt gaattagaaa gaaaccaaat aactattact tatgataaat
    63181 cttttaaaat aagtggagaa gaagacatta tatataagca aagattgaac atattaaaat
    63241 cgtattctta tctttttggt aaggaaaaat ctgatttaag tgtatttgag aagtatttag
    63301 tgaatgtaat tgaaaaaata ttcaaaggga tttatttgat tgatatatat aattggtcta
    63361 tgaatttatt attgcaaatg ggatggactt taaatgatga atcttttaca tggtatgtgt
    63421 cgaacatttt cctttttaca tggtatatac attcagatga aaaacatcct ttagaatctg
    63481 cttcattaag tgagccgtgt tttgaaaata agtttgacca agaatttgaa acaattattc
    63541 aaaaaaagtt gactaaggaa caaatttttc tgttaaagag ttttgtattt tttacaaata
    63601 aatatgcaag tttaaacgag gatatggatt tgattagtac agaaattata gttcaagacc
    63661 taatttacaa tatgtcagaa atattagaga ttagctttaa agaagatatg attctttata
    63721 aaggattact caatcatatt gctccattga tagagagaat caagcagaat atacagattt
    63781 atgaggaatt acttcatgta ataccagata aatatcaata tgtacttgaa gctactaagg
    63841 tttctattca aaaaaacaga gttttaagtc aaataaagaa tgaaaatgaa acaatacttt
    63901 tggcaataca ttttttagga agtatacata gaaatgagag gaataactac aaaaatatat
    63961 tgttagtttg tggatttgga tatggtgtaa ttgctatgtt aaaggatagt ttagtaaatg
    64021 attaccagat aaatatagta gagagtattc catcatataa gttacaagat tataaagaat
    64081 gggaaagtat tgacttcatt ataacaacat caaagatagt aatagacttg cctaaaacaa
    64141 ttattgagat aaatccattt ttacaagaag aggattattt gaagtttgaa gaaaaaggga
    64201 taaaaagaaa gaacgtctta actaattata tgtcaataaa aaaaaggttg gactttttag
    64261 aagaagatgc ccaaaaaaga gtattaagta ttatatgtca agaacttgga tacagtgatg
    64321 agagaatatt atttagacaa cttaatttaa gtgatttaat agggattgat accataagga
    64381 taattgatgg agatatgaaa tgggaagatg ctgtaaaatt tagttcaaac atacttgcta
    64441 attgtgattt tgtatcagca caatatgctg agaatattat agatatttta aaaaatgtgg
    64501 gtttttatgc tgtaaaagat aacgaatttg ctttactaca tggcaatgat agttcattag
    64561 tcaaagtaag ttcgataagt ttattaatat gtaaagaagc agttagtttt ggagataaaa
    64621 aggttaaaat catattttgc ctagcaagca gagataaaaa agagcaaatt cctgcaataa
    64681 ttaatctaac taaaatggtt tataagacta attttattgc tatgttagaa agtgcaaaga
    64741 caaaagaaga agcagaagtt ttaattcata aatatgagaa ggaggtcact gtatgaataa
    64801 attagttaat gtaaaatgtt catttaaaat acatgttaat tcaaaagaag aagccattat
    64861 atcgttagtt gatgtagtgt caaaagaagg atatttaata gataaaaatc aatttttaaa
    64921 agatgtttta aagagagaag aaacattgtc gacttatatt ggacatggta taggtcttcc
    64981 tcatagtcaa agtgtaggtg ttaaaaactc ttgtattaca ataggaaagc ttgatactcc
    65041 tattgaatgg acagaagaag gagaaaaagt ggatttaata tttttgatat cagtaacaaa
    65101 agacaatgaa aataatcttc atttaaagat tttatcaaaa ttagcacgtt tattgatgca
    65161 tgaaagtttt agaaatcaaa ttagatgttc agatgaacaa actgtttata atcttataaa
    65221 agaaaaaata gaggaggaag attaaaatga gaattttaaa gtttttgcaa aaacatctta
    65281 tgacagcaac atcttatatg attccatttg tggttgcagg aggaatatta tttgctttat
    65341 cagtaacttt aagtggacaa gctgctgttc ctgaaacagg ctggttggct aaactgaatc
    65401 aaattggagc tgctggcttg gctttattca ttcctatatt aggtggatat atagcattta
    65461 gtatggcaga taaaccagga ttagctccag gtatgatagg tgcatattta gcaaaagaag
    65521 taaatgcagg ttttataggt ggtatcatag caggatttat agcaggattt gttgttttac
    65581 aattaaagaa aattaaatta gctcctacaa tgagaacttt aggttctata tttatttatc
    65641 ctttagttgg tacattgatt acaggtggta taattgtatt tttaattgga gaacctatag
    65701 cttcttttat gacatggatg acaaactggt taaatggaat gtctggtgtt tctaaaattc
    65761 ctttaggtgg aatcttagga ggaatgatag cctcagatat gggtggccct ataaataagg
    65821 ttgctgctac ttttgcccaa actcaagttg acacacttcc atatttaatg ggtggagttg
    65881 gcgttgcaat ttgtatacct ccaattggtt taggattagc tacattattg tttccaaaaa
    65941 aatttagcaa ggaagaaaga gattcaggta aagcttcact attaatggga tgtgttggaa
    66001 ttacagaagg agctattcca tttgcaacat cagatccagt tagagtaata ccttgtatta
    66061 tggctgggtc gattgtagga aatattatgg cttttttatt aggatgttta aatcatgcac
    66121 cctggggagg tctgatagtg ttacctgtag ttgacaatag gttggggtat attgcatcag
    66181 tattaactgg agcagtagtt gttgcggtat taatgaaatt agtaaaaaaa gacgtgaaag
    66241 aagatgaaga aattgaagaa gatttagatg aatcaattga attaatattt gaagaattat
    66301 aaatataaat ggaaggaatt tgtataaaaa agtaaatata aaactataaa tttaaaggag
    66361 ataagaatat gaaaattgta gcagtaacat cttgtcctag tggagtagca catacttaca
    66421 tgtcggctga atcacttgaa ttatcagcca aaaaatttgg tatagaaata aaggttgaga
    66481 ctcaaggaag ctctggaata gataatgaat tgtcacttaa agatattgat gaagcaactt
    66541 gtgtaatatt gactaatgat gttgagatta gaaatatgga acgttttaaa ggaaagaagg
    66601 tagtaagaat gagtgtatct gagataatta agaaatctga tgcattaatt aagaaaataa
    66661 aagatacttt tcaataaaaa ttgatttatt ttacatataa ctcaaagatg tttttaaaga
    66721 aatttttatt aaaagcatct ttgaaaatat cttaaaaata gaataaaagg agatatagtc
    66781 atgaaaaagt taccaataaa gactgtcgtg caaagattac taaacttaca agaagagggg
    66841 aaaagtgcaa ctcttttagg aattggtcct atgtcaccaa acttgttaca agcaagtttt
    66901 gaactagcaa aagatgatga ttttccttta atgtttatcg caagtagaaa tcaagtagat
    66961 gcagatgaac taggtggcgg ttatgtaaat ggttggaatc aggaaacttt tacaaaagat
    67021 attaagaagg ttgccgacaa agttggattt gatggtttat attatttatg tagagaccat
    67081 ggtgggccat ggcaaagaga taaagagaga aatgaccatt tgcctgttga tgaagcaatg
    67141 gagttaggaa aaaaatctta tttagcggac attgaagcag gttttgacct attgatgatt
    67201 gaccctacaa aagacccatt tgaaattgga aaagtaattc cactagatgt agtactagaa
    67261 agaactgtag aattaattga gtattgtgaa aacgagagaa aaagacttaa tctaccagac
    67321 ataggttatg aggttggtac agaggaaacc aatggaggtc tgacttcaac tgagacgtat
    67381 gaaacattta taactagact aaaggttgaa ctcgataata gaggtttgcc aatgccaaca
    67441 tttatagttg gtcaaactgg tactttaact agaaagacag aacaagtagg aacttttaat
    67501 tttagaaatg cttatgattt agctcaaatg gctaagaaat atggagttgg tttaaaagag
    67561 cataatggcg attacttaga tgatgtaact ttattagaac atataccatc tcaaattatt
    67621 gctacaaatg tagctcctca atatggtact gaagaaacta gggcatattt aaaattagca
    67681 gaagttgagt gtaaattaga aaaagagggt ttagttgaga aaacttctaa tatcagacat
    67741 gttcttcttg ttaatgcaat tgaatgtgga cgttggagaa aatgggtagt aggagaacaa
    67801 aaaaatctaa ctactgaaga gatatttaag gatgaagttt tatctaatga aatactagat
    67861 attgcaggac attatacatt taataatgat gatgttaaaa aagaaataga agtgctttat
    67921 gataatttaa gtaagaataa tattgatggt caaagatttg ttgtagacca tattaaacgt
    67981 cctttgcgtg attatgcaga atgctataac ttaaaaggtg ttactacgag gattttaaat
    68041 aaataatagg acttatagtg gtgagtattg ttatactagg tatttatagt tataattata
    68101 cttaccacta ttaaatttag gaggactaat attttgatta atttaatttt tgatgtagat
    68161 gatactttat ataatcaatt aacgcctttt tacactgcat ataataaagt gttttcttca
    68221 ataaaggata tttctattga agatttatat atgagtagta gaaagtatag tgatgaggta
    68281 tttcatatga ctgaaaatgg agaaatgcca atcaaagaaa tgcatattta taggataatg
    68341 aaagcttttg aggagttggg aaattctatt acagaaaaag atgcacaaag ttttcaagat
    68401 gagtatatat atcaacaatc acaaattaca ctaataccag aagttgagag gattttaaat
    68461 ttttctaaag aaagaaatat taatctagga attataacta atggcccatc aaaccatcaa
    68521 agaatgaagt taaagcagtt aaacattgaa aactgggttg ataaaagtaa tatttttatt
    68581 tctagtgagg ttggattttc taagccagat actaatattt ttagagtagc tgagaatgtt
    68641 atgaatttag atagagaaaa tacatattat gtgggtgatt cttatagaaa tgatgtatta
    68701 ggtgctaaaa aagctggttg gaagagtata tggttgaacc atagaggaca tgaggtagaa
    68761 gagttgtttt ataaacctga ttttgtaatt ttggaacata aggatttgat atctttattt
    68821 ataaaaatat gtagttataa aaatatgtag taaaaaaatg ttaataatag aattgtataa
    68881 aataattaat aataactata taaaattata tgtttagatt gtgagcaatc tattttatgt
    68941 taaaaataga ttatttagaa gaaggggaaa tcttaaaaaa atttgaatat ccccttttta
    69001 ttatttaatt aaaatgaaat agttagaaat atattttatt tagtttagtc aataacattt
    69061 tgggattctt tataactaca tgttaactgt tgaataggtt tatcatatgg tttaacccat
    69121 cctttattaa tacttaattc tgtaagtgct gtgtgacctt ctaccatttg agttaatgaa
    69181 gctgaatata tagctcttaa ttcaggtgta ctacttgtca atgcagaatt aagatacata
    69241 ttggcagatg ctttagcaga tgaaagcata cttaacatta ttactttatc gtctatataa
    69301 gtattgttct taattagatt ttctatcata tttctcatgt tatctatacc tcctcagaaa
    69361 ttagtatttc attttcaact ataaattgtt gtatagcttt aattcttcct tctgttgcta
    69421 atatactaga ttctgattgt ctttttaggt cttcatctga tattaacata tttattgctc
    69481 tttgcataag taatccgtca gactccattt ttataattgc tgctaaagat attttttcag
    69541 tttctgaaag tattctcatt taatcatctc ctatattgta atttatgctt taatagtatg
    69601 tctttctttt caaggaaata accattacac ttttttacag tattttatat tctctttata
    69661 tcaaaattta gtcgacctaa ttaatataat tttgtaggat atttatcatt aaatatctat
    69721 aaaataaatt atttgaatat tcataaagca aaatttattt gtatgtactt cttcaagagt
    69781 caatatgagt tttttcaaaa aattaatttt tatgataatc attaagggct atatttttct
    69841 taaagttgtg attatcatta ttaatttacc ttagaggtta attaggtgtt taatcaaagt
    69901 taatgccttt agaatacaaa tgtattctaa aggcattttt actatgtatt ttcatttata
    69961 ttactaaaca ttatctattt ttatatacat ttctatgtat tttattttca tcaaatcggt
    70021 ctataaactc atttttttct tcactatatc caatagatat aagtgcataa ggaactaatt
    70081 ttaatggtaa gtctaaagtt tgtctaactt tatttaccac tttattttta ggaaatactc
    70141 ctgcccaaca agcagctaga ccttgattag taacttctaa taataaattt tgtgtgcaag
    70201 cacctaaatc ttgtatccat ttaccaggtt ttaagaattt atctctattt ccaagcacta
    70261 ctatacataa tggtgcaaat tctatatgct ttgctctatg ctgtgacttt gagagctgtt
    70321 tcagcagttc cttatcatct actataataa attcccaagg ttgagcattt tttgatgaag
    70381 gtgcttgcat agctgatttt agtatttcag ttattttatc ttcttctata tttttatcta
    70441 tatatgttct tattgaacgt ctatttttta taacttctaa catacagatt ctcctttaaa
    70501 taaaattatt tctatttata taatatcatt actttaaatt ttagctatta cttatataaa
    70561 gaataaactt tgtgttggtt ttatctaagt aaaagtaaca ttcagaacta aaaaacaaga
    70621 ctataaatcc aaagtattaa ttaaaaaaga agtaataaaa aataatatac aagatttaaa
    70681 aaagagtatt gggcttaaaa tttaattaga aaaccaattt tgagataatc tgttttttat
    70741 tttaacaaaa aaacataaat aaagttcgat acgtagcgaa tgaaaaaatt acaagaaata
    70801 ttttttttta aaaatttcaa aaaagagttg ataatatatg tatattaata taaaatttaa
    70861 ggtgtataat tcgtataata atacgaatga tttgtagtgt aaaataactt ataaacggag
    70921 aggggaagtc taatgaaagt agcagtagtt atgggttcaa aatcagatta tccaaaatta
    70981 gaagaaggga taaaactgct tgaaaaatat ggaatagaag ttgtagcaag agcattatca
    71041 gctcatagaa caccagaaca actttcaata ttcctaaaag aaatagaaga tgatactgat
    71101 gtaataatag cagcagcagg aaaagcagca cacttaccag gtgtaatagc ttcacaaaca
    71161 ttaattcctg taataggatt acctattaaa tcatcaacta tggatggact agactcactt
    71221 ttatcaatag ttcaaatgcc aaaaggaatc ccagttgcaa cagttacaat agacttaggt
    71281 ttaaacgcag ctttattggc attacaaata atgactttaa aatacccaaa attaaaagag
    71341 gatttgaaat catatagaga agagatggca caaaaggtgt tagaagacga caagaattta
    71401 agggggtagc agaaatgtta ttatatgaag gaaaagcaaa acaagtatat tctacagata
    71461 atgaaaatga atatgttgtt tattataaag atgatgcaac agcatttaat ggagaaaaaa
    71521 aagcagaaat atcttcaaaa ggtatactaa ataataagat atcaacaata atctttgaaa
    71581 tgttaaaaga aaataatata aatactcact ttataaaaag tttatcagat agagaaatgt
    71641 tagttaaaaa agtagagatt ttaccattag aagtaatagt aagaaatatt gctgctggtt
    71701 ctatctgtaa aagagttggt cttgaagaag gtgtagtttt cgatgagcca atttttgaaa
    71761 taagctacaa aaatgatgct tatggggacc caatgctaaa tgatgattat gcagtggcaa
    71821 tgaagttagc aactagagaa gagttaaaat tcttaagaga agaaacttta aaaataaatg
    71881 agttactaaa agcatttttc ttaaaattaa acctaaagtt agttgacttt aaaatagaat
    71941 ttggtaagga ttctgaagga aatataatat tggcagatga agtatcacca gacacttgta
    72001 gactttggga tgtaaataca aatgaaaagt tagataagga cagatttaga aaagaccttg
    72061 gagaccttgt agaaggttat acagaagtac tttcaagaat gaataataaa taggaggcaa
    72121 atgtatgtgt ggagttttag ggatttactc taataaagat gtaactaaag aactatatta
    72181 ttctttatat tctatgcaac acagggggca agaaagctgt ggtttagctc ttttagatga
    72241 tggagaaatt aagtacaaaa aagatatggg attagttgga gatgttttta aggaaaatga
    72301 attatctaag ttaaaaggaa atatagggat tggacatgtt agatattcaa cagctggagg
    72361 aagtcatgtt tctaattgtc aacctttagt tggaagttgt agaaaaagac aattagccat
    72421 agctcataat ggaaatctag ttaatgcaaa ttatttaaaa gatatgctag aagaagatgg
    72481 atatatgttc caaactaatt cagatacaga agtgatttta tatatacttg ctagatatta
    72541 caaaggggat atagtagaaa gtttaaaagt gacaatggat tatataaaag gtgcatatgc
    72601 tcttgtaata atgagtcaag aagaattggt tgcagttaga gacccacatg gattcagacc
    72661 tcttgtactt ggtaaaaagg gtgatgaata tatatttgca tcagaaaatt gtgcaataga
    72721 tatacttggc ggagaagtta taagagatgt agagccagga gagataatag tagtcaaaga
    72781 tggagaacta aaatcatatt tttattcaga aaattataaa ccagttaaga aaagttgtat
    72841 atttgaacac atatactttg caagaaatga tgcaactata gacaatgtaa atgcatatga
    72901 atttagaatt aaatgtggtg agagattagc tcagaatgaa actgtaaagg cagatatggt
    72961 agttccagtt ccagattcag gttggccagg agctattggt tatgcaaatg ctagtggatt
    73021 aaaaataagt gaaggcttag ttaaaaatag atatgtagga agaacattta taaaacctac
    73081 acaagaagaa agagaaatag cagtaaaaat aaaattaaat cctctttcaa caataataaa
    73141 aggaaaatct ataattttag tagacgactc aattgtaaga ggaactacat ctaaacaatt
    73201 agtaaaatct ttaagagaag caggagcaaa agaaattcat cttagaataa cttctcctcc
    73261 agtagcttac tcttgttact atggaataga tactccaaat cgctctaaat taattgcatc
    73321 aagtaacaac gtagaagaaa tgagagaata tattggatgt gatagtttaa aattcctaga
    73381 tatagaagga atgttagatg caacagaaca taagtctact ttctgtaaag cttgttttga
    73441 tggagaatac ccagttaaga aaattgataa ggaggaacta ctttcatgtt aacatataaa
    73501 gaatcaggtg tagatataga tgaaggaaat agagcagtag accttataaa aggtaaaata
    73561 aaaggaactt atgatggaaa tgtagttgga gatttaggta acttcagtgg attatacagt
    73621 ttaaaagatt ttgtaggtat gaaagaacca gttttgcttg catctacaga tggtgttggg
    73681 actaagttaa aaatagctca gatgatggac aagcatgata ctgttggaat agatttagtt
    73741 gcaatgtgcg tgaatgattt aatttgtcaa ggagcaaaac cattattctt ccttgactat
    73801 atagctcttg ggaaattagt gcctgagcat atagaaaaaa tagttggtgg aattgcagat
    73861 ggttgcaaaa tgtctggttg tgcactaatt ggtggagaaa ctgctgaaat gcctggaatg
    73921 tatggagaag atgactatga tttagcagga ttttctgtgg gaatagcaga caaagaaaag
    73981 attgtttctg gaaacaatgt taaatcagga gatgtattgg ttggtatatc ttcaagtgga
    74041 gtacacagca atggattttc ttttataaga aagatatttt tagaaactta caattataaa
    74101 atggaacaat atgttgaaga actaggaatg acagttggag aagcactttt aacaccaact
    74161 aaaatatatg ttaaattagc tttagatgta ttagctaaac atgacataaa agctatagct
    74221 cacataactg gtggagggct tatagaaaat ataacaagag ttatacctaa agggttagga
    74281 ctagatatca ataaaaaatc ttgggagaag cctcctatat ttaaaatgat agaaggtttt
    74341 aatgctgttg atgagagaga acttcataag agttttaaca tgggtattgg gctagtttta
    74401 atagtagata aagaaaatgc tgatgatgtt gtaaacttta taaataatag agaaaatgac
    74461 aatgctgatt atgtagataa aaaatatagt gaattattag aagataaagc ttatataatt
    74521 ggtgaagtag tagatagtca tgaaggtgta gaattatgct aaatatagga gttttaatat
    74581 ctggtggggg aacaaattta caagcagtta tagatggtac tgagtctgga gaaataaaag
    74641 gtcaggttaa agtagttatc tcaagtaagc aaggtgctta tgggctagag agagctaaaa
    74701 atcataacat aaaagcaatt tgtgaaactg atgaagacaa gataatagaa attcttaagg
    74761 aaaataaaat agatttagta gttttggctg gttatttaaa aataatcagc ccaaagctgg
    74821 ttaatgagtt tagaaacaaa atgataaaca tacatccatc attaattcct tcattttgtg
    74881 gagctggatt ctatggagaa aaagttcatc aaggtgttat agattacgga gctaaagtaa
    74941 ctggtgctac agttcatttt gttgatgaag gtgctgatac tggaccaatc ataatgcaag
    75001 atgtagttaa ggtaaatcaa gatgatgatg caaagacact tgcaaaaaga gtgttagaag
    75061 ttgaacatag gattttaaaa gaaagtataa gtcttttttg tgaaaataaa ataaaacttc
    75121 aaggtaggag agtgtttata aatgagtaag agagctttaa taagtgtaac tgacaagact
    75181 ggtgtagtgg aatttgctaa agagttaaat aaattagatt atgaaattat atctacagga
    75241 aatacattta aaacattaaa agaaaatggt gttaatgtaa tgcaagttga agatgttaca
    75301 aattttccag aaatattaga tggaagagta aaaacattaa atccatatat acatggtggt
    75361 atactttata aaagagataa agaatctcat gtagaaactg taaatgaaca caaaatacat
    75421 tcaatagatt tagtagctgt aaatctatat gattttgaag gaactttaaa agctggaaaa
    75481 agtcatgatg aaataattga aaatatagat attggtggac catctatgat acgttctgct
    75541 gccaaaaact ataaggatgt aatagtagta gtagatataa aagattatga ttctataata
    75601 gaaaaattaa aaacagatac aatgacatta gaagacagaa aaaaattatc atataaagct
    75661 ttctcaacta caggaagata tgatgcgtta atatctagtt attttgctgg agaagttgga
    75721 gatacgtatc ctgacatatt aaatttaact ttccaaaaag aacaaacttt aagatatgga
    75781 gaaaatccac atcaaaatgg tttcttatat tcacagtcaa atgcaaaaaa tccaatctta
    75841 aattatgagc aattaggcgg taaagaactt tcttttaaca acttaaatga tttacatgga
    75901 tgtttagaag taatgagaga atttaaagat agtgaagaag tagtttcagt agctataaaa
    75961 catgctaatt catgtggggt agggttagga aaagatgctt ttgaagcata tacaaaatgt
    76021 tatgaagcgg ataaggtttc aatatttgga ggaatagtag gaataacttc tactatagat
    76081 aaagctacag cagagaaatt aaatgaaata ttcttagaaa tagtagtagc atatgatttt
    76141 gaaccagaag ctttagagat acttaaacaa aagaaaaatc taagaatatt aaaattagct
    76201 aaaatagaaa atagtttaca accatatgaa atgaaatatt tagatggaaa attattgata
    76261 caagatagaa acaatatatt agcagaaaaa agtgaaaatg taacaaagga aaaaccaaca
    76321 gatgcacaac ttaaggacat ggaatttggt atgagagtag taaaaaatat gaaatcaaat
    76381 gcaattgcaa tagtaaaaaa tggacaaact ctagctttag gttgtggaca aacatcaaga
    76441 atttgggcat taaaaaatgc tcttgaaaat aacaaagata aagattttac aggagctgtt
    76501 ttagcgtcag acgcattttt cccatttgat gattgtgtaa cattagctca tgaatatgga
    76561 atatcagcag tagttcaacc aggtggctct ataaaagata aagattcaat agaagcttgt
    76621 gacaagtatg atatggttat ggtatttaca ggaataagac acttcaaaca ctaaggagga
    76681 tattatgaag atattggttg taggcggtgg cggaagagag catgctatat gctggaaact
    76741 aagcaaagaa aaaaatgtag aaaaaattta ttgtgcacca ggtaatgcag gaattgcaaa
    76801 cgtagcagaa tgtgtaaata taggtgatac taatatagaa gaacttttaa aatttgccaa
    76861 agaaaatgaa ataggtctga caatagtagg accagaagta ccactagtta tgggaatagt
    76921 agatgagttt gaaaaagaag gattaagagt atttggacct aataaaaaat gtgctcaact
    76981 tgaaggaagt aaagcttttt caaaagaatt tatgataaaa cataacatac ctactgcaaa
    77041 atataaagaa tatacaaact tagaagaagc tatatcagaa atagatagtt ttggatatcc
    77101 agtagtaata aaagcggacg gattagctgc tggaaaaggt gttgtaatac ctgaaaatag
    77161 agaagatgct atagcaactt taaaagaaat gatgtcagat aagaagtttg gagctgctgg
    77221 agataaaata gtaattgaag agtttttaaa aggaatagaa acttcaattc tagcatttgt
    77281 agataatgat acaatagttc ctatggcaag tgcaaaagac cataaaaaag taaacaacta
    77341 tgagcaaggt ccaaacactg ggggaatggg aactttttca cctagtgaaa tatatacaga
    77401 agaattagca aataaagtaa aagagacagt attagaaaaa actttagaag gcttcaaaaa
    77461 agatggactt aattttaaag gtattttatt tgttggtctt atgataactg aagatggaga
    77521 aaaagtactt gaatataatg taagatttgg agaccctgag acacaatctg ttttatttag
    77581 attagaaaca gatttacatg agataatgga agctatacta gataataagt taaaagatat
    77641 agaaataaac tatagtgatg atgaagctgt gtgtgttatg cttacatcag gagggtatcc
    77701 agacagttat gaaaaaggga aaattataac tggtcttgaa aacttggatg atgatatagt
    77761 agtattccat agtggcacta agatgtttga tggtaatttg gttaccaatg gaggaagagt
    77821 aattggtata actgcaaagt caactacagt taaggatgca gcagaaaaag tttatgaaaa
    77881 cataaagaag ataaactttg aaggaatgca ctatagaaca gacataggaa gataattttt
    77941 ctaaaatgga ggataaggta tgttgaatac tgaaaataaa gactcaatgg ttagaagagt
    78001 attagttgaa aaaagagaag gttttgacct tgaggctaaa gctttaaaaa aagacttagt
    78061 agaaagttta cacatagata atatagaaaa tttaagaata ttaaatagat atgatgtaga
    78121 aggaatatca gaagaagttt atgaaaatgc agcaaagaca atattctctg aaccaaattt
    78181 agatgtagta tattatgaag aaataccaaa attaaatgat gaaagagtat ttgcaataga
    78241 atttcttcct ggtcaatacg accaaagagg tgattgggca gctcaatgtg tacaaattgt
    78301 aaatcaaggg ataagacctg ctattaatac agcaaaagtt tatatattat caggcaaaat
    78361 aactgatgaa gagttttcta aaataaaaga ttactgtata aatccagtag atagtagaga
    78421 agcatcttta gaaaaaccag aaacgttaaa aatggaaact gaaataccaa caacagttga
    78481 agtattagat ggatttatag atttagatga aaatggatta aaaacatttg taagtgaaaa
    78541 aggattagca atgactttag gagacttaca acacgttcaa aaatacttta aagatacaga
    78601 aaagagaaat ccaactataa cagaaataaa agtattagat acttattggt ctgatcattg
    78661 tagacatact acttttatga ctgaaataga aaatgtaaag atagaagatg gtaagtttaa
    78721 tgatatagta aaagaagcgt atcaaatgta tcttaactca agagacaatg tatatgtgaa
    78781 cagacataaa gatatatgtt taatggatat agccactgtt gcagtaaaag aattaaagaa
    78841 aaatgggaaa ttaaatgacc tagatgaaag tgaagaaata aatgcatgta gtataaacgt
    78901 agatgttgaa gttgatggta agatggaaaa atatctagta atgtttaaaa atgaaactca
    78961 caaccatcca actgaaatag aaccatttgg tggagcagct acttgtttag gaggagctat
    79021 aagagaccca ttatcaggaa gaagttatgt ttatcaagca atgcgtgtta caggaagtgc
    79081 tgacccaaga acgactttag aagatacttt acctggaaaa cttatgcaaa gaaaaataac
    79141 tacagaagct gctcatggat atagttcata tggtaaccaa ataggtctta caactgggca
    79201 agttgcagaa gtatatgatg aaaactttgt tgcaaagaga atggaaatag gtgcagttat
    79261 agcagcagca ccaaaagaga atgtagtaag agaaagacct gaagcaggag atgtaatcgt
    79321 tcttcttgga ggaaaaacag gaagagatgg ctgtggagga gcaactggtt catctaaaga
    79381 acatagtgaa gagtcaatct taacttgtag tgcagaagtt caaaaaggag atgctcctaa
    79441 cgaaagaaaa atacaaagat tctttagaaa taaagaagtt gctcaaatga taaaaagatg
    79501 taatgatttt ggagcaggtg gagtttgtgt tgctatagga gagattgctg atagcttaga
    79561 tataaactta gacttagttc ctaaaaaata tgatggactt gatggaactg agcttgcaat
    79621 ttcagagtca caagagcgta tggcagtagc cataaaaaaa gaaaataaag ataaatttat
    79681 acaattagca gtagaagaaa acttagaagc tacacatgta gctacagtaa cagatacagg
    79741 atatttaaga atgttctgga atggaaaagc aattgtagat ataaatagag agtttttaga
    79801 tacaaacgga gtaaaacaaa ctactgatgt tcatgttact aaagtagatg aagaaaatac
    79861 attctttagc tctaatgaaa tagtaaaaga tgttaagtgt gcaagtatga aagacaagtt
    79921 tacaaaagta ctatctgacc ttaatgtttg ttctcaaaaa ggattagtag agatgtttga
    79981 taatacaatt ggtggtaata cagtccttat gccatttgga ggaaagtatc aagcgactcc
    80041 aacacaaggt atggttgcta agataccagt acttggagga gaaactaata cttctacaat
    80101 aatgacttat ggatacaatc caaaggtagg aaaatggagc ccattccatg gtgccttata
    80161 tgcagtagta gaatctgtgt gtaaattggt tgctattgga ggaaattata gtacaacaag
    80221 acttacattc caagagtatt ttgaaaaact tggtaacaat ccagaaaaat ggggtaaacc
    80281 attctcagca cttttaggag cattttatgc acaaagtaaa tttgagatac ctgctatagg
    80341 tggaaaagac agtatgtctg gtacatttaa agatattgaa gttccaccaa cattagtttc
    80401 atttgctgtt gacacagtag atgcgaagaa agtagtatct ccagaattta aaaaagcaga
    80461 ctcaaaagta gtaatgttat gtgtaaacaa ggcagaaaat gatgttgtag attttgagga
    80521 attaaagaga aacttagata aagtaagaga acttatacat ggaaataaag ttttatcaac
    80581 atatgcatta ggatttgcag gtgtaggtga agcaataagt aaaatggctt ttggtaataa
    80641 aataggattt aagtttagtg aagaggctga aaaagcattt acagatgata aattatttga
    80701 ggctagttat ggaaatatag tacttgaatt agcaaatgat gatttaagta tgttagaagg
    80761 atacaattat gttgtgcttg gaagtacagt taaagaagct agtatattta tcaaaggtga
    80821 agaacttgca ttagatgaat tatataaagc acattgtagt actttagagc ctatattccc
    80881 aactaaaaca gaagaagtaa aatcaaagat agaaactata agttatatat cacaaggaga
    80941 agctaaaaaa tcatcattaa gtatagctac tccaagagta tttataccag cattccctgg
    81001 aacaaactgt gaatatgact ctgcaagagc atttgaaaga gcaggagcta atgcaagtat
    81061 aagagtattt aagaatttaa cttataaaga catagaagat tctatagata caatagtaaa
    81121 cgaaataaaa tcttctcaaa taataatgtt accaggtgga tttagtgctg gtgatgagcc
    81181 agatggttct ggtaaattta tagctactgt atttagaaat cctagagtgc aagaagctat
    81241 aaatgaattt ttaactcaaa aagatggact aatgttaggt atctgtaatg gattccaagt
    81301 attaattaaa ttagggttag ttccatatgg agaaataaga gttccaagtg aaagtgctcc
    81361 aacacttact tacaataata ttggtcgcca tcaagctaag attgctagaa ctagaatttc
    81421 atctaataaa tctccttggt tagctcaaac taatgttgga gatattcata atatagcaat
    81481 ttctcatgga gaaggtaagt ttgttgccag tgaagatgtt atgagagaat taattgctaa
    81541 tggacaagta gcaactcaat atgttgactt taataatgaa gctacttatg atattgagtt
    81601 taatccaaat ggttcattct atgctgttga aggtataact agtgctgatg gtagagtgtt
    81661 tggtaaaatg ggacattctg aaagaattgg tgaggaagta tataagaata ttataggtga
    81721 aaaagaccaa aagatatttg aatctggagt taaatatttt agataaagct ttgatgttta
    81781 attgatagct agaatatata atttagatat ttagatttaa agagatgtaa taatatgatg
    81841 ataatcattt aatattacat ctctttttta tttatctaag aaataataag ttcaacctaa
    81901 gttaaaatac aagctgtgtt ataattaatt attaagtaaa attgaatatt tattggaggg
    81961 caacataatt aatgaaaata ttaataacag ggtctaatgg tcaattagga aaagaattgg
    82021 ttaaccaatt agaagcaatt aatcaaagta taaaccaacc aaaatatgtt atattagcta
    82081 caacaagaag tgatttggat atatccaatc agactaatgt agataatttt attttgcata
    82141 ataaacctga tgtagttgta aactgtgcag catatacaaa ggttgatgca tgtgaagata
    82201 atatcgaaat tgcatacaaa ataaatgctt taggagtgag aaatctagca atagcatcag
    82261 aaaaagttaa tgctaagctt attcacatat caactgacta tgtattcaat ggtttttcta
    82321 aatatccata tagggaagac aataaaactg aacccaattc tgtatatgga aaaagtaaac
    82381 ttatgggaga aaaatttgtt gaacaattct cacataagta ctttatattg agaacagcat
    82441 ggttatatgg taatgggaat aattttgtaa agaccatgat aaaactttct ttagaaaata
    82501 aagaggttaa tgtggttaat gaccagtttg gaactccaac aagtacagta gacttagcaa
    82561 aaattataat aagaatcatg gaaacagaac attatggagt ttatcatgct acatgtgaag
    82621 gtgagtgtag ttggtatgat tttgccaaaa agatatttaa actaaaaaat atagatataa
    82681 aagtaaatcc aattaagagt aacgaattta aatgtaaggc tccaagacca ctatattctg
    82741 tattagataa ttttatgttg aagttaattg gtttaaattc ttttagaaag tgggaagaat
    82801 ccattgaaga atatttagaa agatatgata taaatgaaaa gtaaatgtat tattttgaga
    82861 aaagaaaata agatattata aaaaatataa atatttcttt tatttatccg ataatcataa
    82921 tatgacaaaa acaaatttaa ggatggaaaa agatgaaagg aattatttta gcaggagggt
    82981 ctggtacaag actatatcct ataacaaaat gtatatcaaa acaaacactt ccaatatacg
    83041 ataaaccaat gatatattac cctatgtcgg ttcttatgtt ggcagggata caagatatat
    83101 taataatatc tacaccaaga gatataaaag catttgaaga attatttgga gatggaagtt
    83161 cactagggat taacataaca tatgcaattc aggagaaagc aaatggaatt gcagaagcgt
    83221 ttataatagg agaagaattt ataggaaatg acagagtgtc tcttgtatta ggggataata
    83281 tattttatgg atatggattt agtgaaaggt tggagaatgc agttaaaaga aaaggagcaa
    83341 ctatatttgg gtatcatgta agtaatccaa attcgtttgg agttgtagaa tttgataagg
    83401 attttaatgt attgtcaata gaagaaaaac ctacagttcc taaatctaat tatgctatac
    83461 caggattata tttttatgat aatgatgttg tagagatagc aaagctagtt gaaccgtcag
    83521 atagaggtga attagaaata acctctataa acagtgaata tctaaaacga ggaaaactaa
    83581 aagtggaact tctaggaaga ggtatggctt ggcttgatac tggtacacat aaaggtctat
    83641 tagatgcttc taattatgtt gaagtggttc aaacaagaca gggattgtat atagcatgtt
    83701 tagaagagat tgcatataca aaaggatata taagtagaga acaattaatg aaactagcca
    83761 agccactgat aaaaactgaa tatggtcaat atctattaaa attggctagt gaagatatgt
    83821 aatatggtag ataaaattta ttataaattt tattaaggga gtttattata atgggaaaaa
    83881 tcaatgttat aaagactaaa atagaaggat tatatatagt cgaaccaaat gtattttatg
    83941 atgaaagagg atattttatg gaaagctata ataaaaagga ttttatagag cagggtcttg
    84001 atatgtgttt tattcaagat aatgagtcta gctcaagaaa aggcgtttta agaggaatgc
    84061 attttcaggt taaatatcct caaggaaaat tagtcagagt tacagaggga gaagttttcg
    84121 atgttgcagt tgatttaagg aaagattcac aaacatttgg gaaatgggaa ggtgtaatat
    84181 tgtctgataa gaataaaaaa caattttata ttccagaagg gtttgcacat ggatttttag
    84241 ttttatcaga aaaagcagta tttagttaca aatgtacaaa ttattattac ccagaatttg
    84301 agaatggttt tatatggaat gataagcaaa tatctattga gtggccttta aaaggaattg
    84361 aagaaatatt tttatcagaa aaggacaaaa aacaaaaaag ttttaaagat atttgtacaa
    84421 gacgttaata aaaatttatt agaattaaca tttaggagaa aaaatatgaa aaaaatactg
    84481 ataactggag gagcaggatt tattgggagt aattttatac attatatgct taacaagtat
    84541 gtagattatt ttattgttaa cctagacttg ttgacttatg ctggtaattt agagacatta
    84601 atagaaatac aagacaattc caattataaa tttgttaaag gagatatttc aaatagggag
    84661 caggtgtata agctatttga agaagaaagg tttgatatag ttgttaactt tgccgctgaa
    84721 tctcatgtag ataggtcagt tgagaatcct gatttattta ttaaaacaaa cattatagga
    84781 acacaagtac ttttagatgc atctataaaa tatggagtta aaaggtatca tcaaatatct
    84841 acagacgaag tgtatggtga tttaccaatt gatagaaagg atttattctt tacagaacaa
    84901 tcttctatca atccaagttc tccatattca gcttctaaag catcagcaga tttattggta
    84961 aattcttatt atagaacata tggattgtta acaactatat ctaggtgttc caacaattat
    85021 gggccatatc attttcctga aaaattgatt cctcttatga ttttaaatgc tttggaaaac
    85081 aaacaattgc cagtatatgg gaatggggaa aatgtaagag attggttaca tgtatatgac
    85141 cattgtactg ctatagactt aataatacat aaaggaaata taggggagat ttacaatata
    85201 ggaggtcata atgaaagaag taatctagaa gtagtaaaag tgatattaaa tcttttaggt
    85261 aaatctgaag agttaatatc ctatgtaaat gatagacctg gtcatgattt aagatatgct
    85321 attgatgcaa ctaaaataga gaatgagtta ggttggaagg caaaatatga ctttgatttg
    85381 ggtataaaag aaactgttaa gtggtatata gaaaatgaat cttggtggaa agctgtttta
    85441 tcagtataac tttaaaattt agaaaggggc gttttatatt gaatgagata agttcactaa
    85501 ttaatatatt agcattgact caattatctg gtagtaatac tacaaatcaa tgtaattgta
    85561 catataataa ttcatctgga tttgatatga ttatgatgac cttgttaaaa gcattatcac
    85621 aaaataatca acatacttct aatagctaca atttattgtc taattctgag aatttattta
    85681 atgaacttga taatgtagta aataatacca ctagtagatt tatagatgtt gatacaaaag
    85741 ataaaaatgt aaagttgaga attgaaaatg ctgtagatca agcatcaaaa aaatataacg
    85801 tagattcaaa tcttataaaa gcaataatta aagttgaatc agattttaat ccaaataccg
    85861 tttcttctgc tggtgctaag ggtcttatgc aacttatgcc agaaaactgc agagacttag
    85921 gagttacaga cccttttaat atagaacaga atatagatgc tggaactaga catattaagg
    85981 aatacattga tatgtttgga gggagcatag aaatgggatt gatggcatat aatggtggtc
    86041 ctggaagaat gaaaagtaga ggagtagaat caatctctga cctgtataaa atgccaaaag
    86101 aaacacaaaa ttatattcct aaggttatga aatattatag agggtaggct ttattatggg
    86161 aataaatata gataagctaa acataagtcc aagtataaat atggaggtta aaaaactaaa
    86221 agagagtaat aaattttctg acaaattaaa ctctttaaaa caatcttctt cattggaaga
    86281 tataaaacga aatttggaaa gtgtaaaaaa ggcaggagaa aggcttgtac ttactcaaaa
    86341 ctatggcgat attagtatat ataaaaatgc agtaaaagaa tacctaaaat ctgttgtaga
    86401 taatatgtat tcacttgata aaaatagtag cttttgggag catcagtatt ataagaatgt
    86461 aaagattgtt gatagtaaac ttgaggatat gactagtaag ttaattagtg aagaaaaaga
    86521 aaacatagat attgtttcta ctgttgacat gatacaaggc ttattgatag atatgtatag
    86581 ataaggttat acaaggagaa aaattttatg aatagcaaaa aagaggatat atatgaattg
    86641 aattttgggc aattaataga agaaaaatct ggtgttatag aagaaaatca aaatgttttt
    86701 aatgcaaaag taaatgtagc tgtttctata ggaaatacaa cagaaacaat aaaaaatata
    86761 ttagatttaa aagaaggctc tataataaaa ttaagtaaga atgtggatga aaaattagat
    86821 atatatgcaa acgatagatt gtttgcttat ggagaaagca ttattacaaa tgagaggtta
    86881 tctgtaagat tatctaaaat agaagatcca gatgtaaatt agcattttaa atagtatccc
    86941 tttaggctat tctgtatgag tttagctaag gggatatttt tataaaaaat ttaaaatatg
    87001 tgtgaattat ataaatattt ttattttatg agcgataact aaattataag tatgtaattt
    87061 tggaggtgaa actatggata ttaaaaatgt aagttcaaac attgtagtga ataattattt
    87121 aaagaataca tctggtataa aaaaagtgga agaggttaaa aaaattaata aaacagacaa
    87181 gatagagtta tctaaatttg caaaggaaat ggcaagtgtg tcaaatatga gtgatgagaa
    87241 tattagaaat aaaaaagtcg atgaaataaa aaatgcatta gaaaatggaa cttacaaaat
    87301 aaaaccaaaa gaaattgcga aaaaaatgat agaggatatg cgaggataaa gtcatgatta
    87361 cagacttaaa agttataata tatgaagaaa aaaatataat tagtaagatg atggaattat
    87421 taaaagaaca atttgattat atagttgaaa aagacttaga aaatttaaat atgttaaatc
    87481 ctaaactaga agatattagc agggagcttg catccataga aataaagaga agacaacttt
    87541 ttggtgatga tatttcaatg agtgaagttg ttgaaaatag taatgatgga tacttaaaag
    87601 aaatatatac agacttgaaa cacattcttg ctttagctaa aaatcaacaa gaatcaaatg
    87661 attctctaat aaagaaagaa cttattttta cgaaaaaaat gattaatttc ataaaaccag
    87721 ctgataagaa aactacaact tataattctt atggaaatat tagaaaataa atattaggag
    87781 gagaaatatg gcaggattat tttccatttt aaatacagct aattcaggaa tgaatgcgca
    87841 ccaaaaagca atacagacaa tttctcataa tataagtaat ctagatacag acggttattc
    87901 taggcaaagg accgagtttg ccacaaatag tccaatgtat atgcctagtt tgagtaattc
    87961 aattgcaaga ggacaattag ggactggagt acatgtaacg gatgtaacaa gagctagaaa
    88021 tagtttttat gattaccaat ttagggcaga agctcataag tatggtaaga cagtttcaaa
    88081 atatgattat tacaatacta tagaaactat actaaatgaa ccatcagact atggaatatc
    88141 tgcaggtata gatgattttt ttaaaggatg ggagtcatta tcaaaggata taaatagtga
    88201 cagtaaaaaa agtctagtgg tagaaaacgc atctaattta gcaactttaa taagtgaaag
    88261 ttataagaag cttgataagt taaaagaaga tatagattct aatatagaca ctgagataaa
    88321 acaaataaat gacatgttaa aaagtcttga agatttaaat aaatctattg atattatatc
    88381 tggttctggc tctacaccaa atgatttact tgatgaaaga gatagaattt tagataactt
    88441 gagttttaaa ctagactttg aaaatagtga tgttaaaaat atgcttgcag atggtaaatt
    88501 agaacttaat gaattaaaaa atccagatgg aacttggaaa acaggtatat cagggacctt
    88561 acaaggcttg tttgaaatgc atggtaagat tgatacatat aaaagcgatt taaaagatgt
    88621 atctgatgga ttagctaaac agataaatga tgtttataat acgtctgcag gaataacagt
    88681 aacagatttt tttataactt caaatgtaga tggtgaagat attataaaga taaatccagc
    88741 tataaagagt aacccaaatg aattaaagct tactgctgat gaagcttcaa aaattgctaa
    88801 gttaaaggat gaaaaaatag atattggggt ggctggtgga aaagtaagta caataagtga
    88861 ccactataaa gcctttgcag aatcaatcgg tttagattct caaaaagtaa atcaagatga
    88921 agcaaatcaa cgtaaaatta taaataatat tgataactca agaatgagtg tttcaggtgt
    88981 atctttggat gaagaaatga cagagcttat aaaaatacaa cgttcatatc aagctagtgc
    89041 aaaagttatg tcaacagctg tgcaactact ggatgttgta ataaatggaa taatttaata
    89101 gaagggggaa tttataatga gagtcagtac aggtatgatg tctagcagct atctaaactc
    89161 actacaagat aatctacaaa gattggataa ggttaataga caagttaata caacaaaaga
    89221 aataaacaag ctatcagata atccatataa agcaataaag atattaaact caaaaagtga
    89281 aataaagact atggagactt atgttgagaa ttgtaaagat acagggaatt ggttagaaac
    89341 tactgatact gcattagatc agcttggaaa attattatca gacataaaga aaactttggt
    89401 ggcaagtggt gatggtgcat actcagatga tgaattaaag actcttagta atgaaactaa
    89461 tgaaaaaatg aaagaaattg caaatgcttt aaatgcaaca catgaaggga agtacatatt
    89521 ttcaggttca aatacggggg taccacctgt tgaatgtata gataatgctg atggttcagt
    89581 gagtttaaag tttaattcta gtctaaatct taataaatta aatgactctt tgagtatgga
    89641 tatagctcaa ggaataagtg tagattataa cgttaaattg agtagccttg gatttgaccc
    89701 aacaaaaact gacccatttg aagagttaaa taacatatca aaaaaattag caaatccaga
    89761 tgctgatgct ataaaagagc ttacaacaac ttgtttgggc gatatggaac aactaataga
    89821 aaatacagta aatgttaggt ctatatatgg gacaaaagca aatacagtag aggctatgaa
    89881 ggaaaaaaac gatgatagtt tgatacagtt aaaggatatt ttgtcacaaa atgaagaaat
    89941 agattatggt gaaaaacttg ttcaattaaa ggcagcagag ttaacttatc aagcttcact
    90001 acaaacagga ggaaagttat ttaatgtatc tatattagat tacatataat aaaataacgc
    90061 agatatgatg aaggttacat taaaaaaagg tatattaggt tttgaaaatt taaaagaata
    90121 tgagctttta gatatagaag ataatgatta tttaaaagaa tttaattcta ctgaagaaga
    90181 aggtatagga tttgttgttg tatctccatt tgagattatc aatgaatatg aaatagtttt
    90241 aaatcaggaa acaatagaaa aactagaagt gaaatctcca aaggatgttg tattatttaa
    90301 tataattact cttggtcaga catttgaaga atcaactgtg aacatgaaag ctcctatagt
    90361 gataaatata aaaactaatt ttggaatgca aataatttta caggatgata aatattcaat
    90421 aaggcatcca ttattgagag gtgataatgg atgctagtaa tttcaagaaa aaaagatgaa
    90481 gcagtactta taggagaaag catagaagta aaaattgtag gagtagatgg aaacaatgta
    90541 aaactagcta tatcagcgcc taacaatata agtatattaa gaaaagaaat atacgaaaaa
    90601 gtaaagagtg agaatataaa agctacaaat aaaaatataa aaattttaaa gtcattaaaa
    90661 taataagctt ggaggaagta atatatgtat ggagaaaatc cttataattc ttataaacaa
    90721 aatgctgttt ttatggcatc aaaggaacaa ttgttactta tgcttgttga tggagcagta
    90781 aaatatacta aaatagccaa aacagctatc ttagataaaa atacacaaaa agcgcataga
    90841 gagcttataa gagttcagga tatatttaca gaactaatgg ttacattaga ccaaaatgca
    90901 ggtcaatggg caaaggatat gtacagagtt tatgattttg taagatatga actttcaaga
    90961 gctaatatta gaaaagacat tcaaataata gataatgtgt tgcctgtaat agaacaaatt
    91021 aaagatactt ggcatgaagc tgataaaaaa agtaaagaag aaagaagtag gtacaaataa
    91081 tggaattaaa tttagctgaa ttagataagt tatcaaaaga ggaattacta ttgatgcttg
    91141 tagatggaac agtaaaatat accaatatat ccaaagaagc tcttttaaat aacgactatt
    91201 tgaaagcaca taatgaactt gtaagagttc aaaatatatt tacagaacta atgactacat
    91261 tagaccaaga tgcaggtcaa tgggcaaagg atatgtataa agtttatgaa tttataaaat
    91321 ctgaattagc aatagctgat gaaaataaag atattaaaat aattgatgat atattgccaa
    91381 tagtaaaaca aattagagat acatggcatg aagtttacaa tcaactaaaa atataattgg
    91441 atggagggat aaaggtatgt caagtataag tcctataaga gttacaggtc tttcaggaaa
    91501 ttttgatatg gaaggcataa tcgaagctag tatgattaga gacaaggaaa aagttgataa
    91561 agcaaaacaa gaacaacaaa tcgttaaatg gaagcaagaa atatatagaa atgttataca
    91621 agaatcaaaa gatctttatg ataaatatct aagcgtaaat tctcctaata gtatagtaag
    91681 tgaaaaagca tactcttcta caagaataac cagttctgat gaaagtatta tagtagcaaa
    91741 aggctcagct ggtgcagaaa aaataaatta tcaatttgca gtttctcaaa tggctgaacc
    91801 agcaaaattt actattaaat taaattcaag tgaacctatt gttcaacagt ttcctccaaa
    91861 tgctagtgga gcgagttctt taactatagg agatgtaaat ataccaatat ctgaacaaga
    91921 tactacaagt actattgtaa gtaagataaa ctccctttgc gcagataatg atataaaggc
    91981 ttcttatagt gagatgacag gtgaattgat tatttcaaga aaacagactg gttcgtcatc
    92041 agacattaat ttaagagtaa ttggaaatga caatttagct cagcaaattg ctaatgataa
    92101 tggtatcaca tttataaatg atgctggtgg aaacaaagtg gcaaatgtat atggaaagaa
    92161 tctagaagct gatgtaactg atgaacatgg aagagtaact catataagta aagaacaaaa
    92221 ttcatttaat atagataata ttgactataa tgtaaattca aaaggaactg caaagttgac
    92281 ttctgtcact gatactgaag aagctgttaa aaatatgcaa gcatttgtgg atgattataa
    92341 taaactgatg gacaaggtct atggtttagt tactactaaa aaaccaaaag attatccgcc
    92401 tcttacagat gcccaaaaag aagatatgac aactgaagaa atagaaaaat gggaaaagaa
    92461 agctaaagaa ggtatactta gaaatgatga tgagttaaga ggttttgttg aagatattca
    92521 atctgcattt tttggagatg gaaaaaatat tattgcatta agaaaactag gtatcaatga
    92581 aagtgaaaat tacaataaaa aaggtcaaat atcatttaat gcagatactt tttcaaaggc
    92641 tcttatagat gatagtgata aggtatacaa aacactagca ggttattctt cgaattatga
    92701 tgataaggga atgtttgaaa agctaaaaga tattgtatat gaatattctg gaagttcaac
    92761 ttctaaactt cctaaaaaag caggtataga aaaaactgct tctgctagtg aaaatgtata
    92821 ttcaaaacaa attgcagagc aagaaagaaa tataagcagg ttagttgaaa aaatgaatga
    92881 taaagagaaa agactttatg ctaaatattc agccttagaa tctttgttga atcagtattc
    92941 ttcccaaatg aattatttct cacaagcaca gggtaattaa ttatggataa attaaaagaa
    93001 aaattaaatt tatataaaga tatatcttta caaattataa atttgattga aaaggaagaa
    93061 tatataaaga taagtattaa gttaggtgaa agacaagaga ttataaatag tgtaagtgaa
    93121 attgatagaa atgattttat acagctttat aatagaatgg aattaattga aattgatagc
    93181 aggataagag atattttaca aggacaatta ttagaagtaa aaaaagaatt acatgagtat
    93241 aagcttacta aacaagtgaa cacaatgtat tataacttaa atagagaaaa agtaaatatt
    93301 tttaataaaa aagtataaag ttatgtacca tcttgtccga ttatataaat gaagaattaa
    93361 taaaaaagat taaaagtaga aatgacaagg atgtcaacta tactaaggag ggtaaaataa
    93421 tgagagttaa tacaaatgta agtgctttga tagcaaataa ccaaatggga agaaacgtaa
    93481 atgcacaaag taagtctatg gagaagctat cttctggtgt tagaattaag agagctgctg
    93541 acgatgctgc tgggcttgct atatctgaga aaatgagagc tcaaataaaa ggtttagacc
    93601 aagcaggaag aaacgttcaa gatggtatat ctgttgtaca aacagcagaa ggtgcattag
    93661 aagaaactgg taacatacta caaagaatga gaactttatc agtacaatct tcaaatgaaa
    93721 ctaatactgc tgaagaaaga caaaagatag ctgatgagtt actacaatta aaagatgaag
    93781 ttgaaagaat atcaagctca attgagttta atggtaagaa attacttgat ggaagttcta
    93841 cagaaataag attacaagtt ggagcaaact ttggaacaaa tgttgcagga acatctaaca
    93901 acaacaatga aataaaagtt gctctagtaa atacttcaag tataatgagt aaagcaggta
    93961 taacaagttc tacaatagca agcttaaatg cagatggaac ttctggaaca aatgcagcta
    94021 aacaaatggt atctagctta gatgtagctc ttaaagaatt aaatacatca agagcaaaat
    94081 taggggcaca acaaaataga ctagaatcaa ctcaaaacaa cttaaataat actatagaaa
    94141 atgttacagc agctgaatca agaataagag atacagatgt tgcttcagaa atggttaact
    94201 tatctaaaat gaatatatta gttcaagcat cacagtcaat gcttgctcaa gctaatcaac
    94261 aaccacaagg agttttacaa ttattaggat aaaataattt tgtatattgg atatagaaga
    94321 aagggtaagg ctttgcttta ctcctttctt tttttacaaa tatacttttg aaaggaaaat
    94381 ttatatgtta cttagtatag ttatgattgt taaaaatgaa gaaaaaatac ttgaaaaaac
    94441 tttaaaatca ttaaccacat taagaaattc tatagaaagt gaacttataa tagtcgatac
    94501 aggttctaca gatgatacta taaaaatatc taagaagtac acggaaaaag tgtattttca
    94561 taattggaat aatgattttt ctagtatgag aaatatatca atatcctatg ctaaaggtga
    94621 atggttactt atattagatg cagatgaaat actaattgat tcttcaacta ttgtaaaatt
    94681 ttttaaagat ggtcttgata aaaaatttaa ttctgcttca atacaattaa aaaatcttta
    94741 ctcatatgat aaaaaattat atggatattg ttcggtgctt agacttttta aaaacgttga
    94801 ttttagatac catggtaaag tacatgaaca accaatatac aaaaacccta tatttaataa
    94861 tgttgctgat tttgaacatt atggatattt gtttgaagat gaagaaataa gattaaataa
    94921 ggtgaaaaga aatgaaaaac tattatttca agagttaaaa gagaatgata attctccata
    94981 tacaaactat caattaggga aaaattttat tatattagga aaatatcagg aggctttata
    95041 ctatcttgag aaatcttatg aattatattc taaactagaa ttggcacctg gttacttgat
    95101 aacaagcctt gtaaaaacat atttatattt aggaaaacat aagaagtgtg aaagattgtg
    95161 cttaaagtat attaagaaag acatgaataa tattgatata tattattata ttgcacaagc
    95221 acaagtagat ttaggaaagt atgaaaatag tatagattcg tataagagat atatttactt
    95281 gttagataat tatgaaataa gtacacaagc aaatagttta ttttcagaca ctgatactgt
    95341 agggcttaga gatgaggcta ttattacact gataaagatt tattataagc ttgaaaaata
    95401 tgagtttgta atttcagagt ataataacat tgaagatgtg gaaaagaaaa agaatgtgta
    95461 ctttagctta tttatgtcac tatataaatt gaatagattt gaagatataa aaaattatta
    95521 taaagaagtt tcaaattcta aaattgaaaa aaatagtttt tatagaaata tagaagaagt
    95581 tataaataat attaaagagg atgaaaaaga gtatgtatat aaaatccttt gtgacattga
    95641 aggtaattat ggcattttaa atcaaataag gataaataaa tgtgtatcta tagataaatg
    95701 taaagaaata ctcaatgaag aaaaggaaat aatttatgca tatattataa aaatagcttt
    95761 tgaagagaag attgatttac tagatatttt ttatgaaatg gaatatgtat ggatagagaa
    95821 atatctaaaa tatcttttag cattagaaag aagttttaat ttagtactat ataagtacat
    95881 aattagtcgt ccaaatacat cagatatgga aaagataaga gtatataaag ctatatctaa
    95941 agtagtttta gaaagtataa gcttaagtga tgaaaaatat aaggagattt tttatcttta
    96001 tataatgtat tcttataagt acataagata catatatagc aatttaagtg attttgaatt
    96061 aataaaattt gtttgtaatg atttagataa gttcactata gaatttaagc atctacttga
    96121 tattaaaaat aaagtaaata atgctaatga aaaattagag tatatacata gtatgaggaa
    96181 attactaaat gagtatcctt tttataataa aataataaaa atacttatag gtgaattaga
    96241 agaaaatata aaagaaagtg aagaatttaa ggatttaaaa gatagtttta ttattagtat
    96301 agaaaatatg attgaaactg gcaaaataaa tgatgcgaaa ttattggtag atgactattc
    96361 aaaaacattt gtggatgata taaagatttt aaatataaag ggaattttat acatgtttga
    96421 aaataagctt gataaagctg attttatgtt aaaaaaggca ttatcattag atgtagaaaa
    96481 tgaagatact atatataata tagaatactt aaaaagttta agataagtca aaaataggag
    96541 aattgaagaa tgaatatacc aatagtggtt aatgaaaaat ctaaagacat aataaaagat
    96601 tggcaatata catgtacaaa tgaagatata aaatttacaa gcataataat attgacatat
    96661 aatcaaatag aatatactaa attatgtatt gaaagtatta ggaaatttac cccaaagaat
    96721 aaatatgaaa taataataat tgataataac tcttctgatg gaacagttga gtggttaaag
    96781 ggacaatctg atataaaatc tgtgtataat aacaaaaact taggatttcc aaaaggatgc
    96841 aatcaaggta ttgagttagc tactggtgaa aacatattgt tgttaaataa tgatgtaata
    96901 gttactccaa attggctcta taatttgaat aaagctttat ggtctcaaga taatataggt
    96961 gctgtaggac ctattacgaa tgcatgttca tattatcagc aaattgatgt tgattataag
    97021 tcaattgagg acatgtttat atttgcacac aaaataaata aatctaatat taacctatgg
    97081 aaatatagat tgaagttagt tggattttgc atgttaataa aaaaaactgt tctggataat
    97141 gtaggggttt tagatgaatt attcacacct ggaaattttg aagatgatga tttatctttt
    97201 aggatgatag agtcaggata taagttatta ttatgccagg atacttttat acaccatttt
    97261 ggaagtgtgt cttttaaaga aaatcgtaat aaatatacag atataatgta tattaataga
    97321 agaaaatttg aaactaagtg gggatttaat ccagaatata gtggaatgat aagaacagat
    97381 ttgatttcta aaatagatga tagtttggag gcaaatatta atgttttaga aataggatgc
    97441 ggtatagggg ctactctttt agaaataaaa aatatatata aaaatgcatc aatatatgga
    97501 atagaaatta gtgagtcagc aggtaaactt gcaaagtata gtgcagatgt acttatagca
    97561 aatatagaaa aagtaaaatt ggattataaa aaagattttt ttgattatat aatattggga
    97621 gatgtacttg aacatttgat tgacccatgg aagatagtca atgaattgaa acaatatcta
    97681 aagaaggatg gttatctggt atctagtata ccaaatatta tgcatgtttc tgttttaaga
    97741 aatcttgtgt taggtaattt tacatatgaa gattcaggaa ttttggacaa gactcattta
    97801 aggtttttta cattaaatga gataacaaaa atgtttaatg atagtaatta cataattaat
    97861 agtattacag ctactagtat gccactttcg gaaattgata atagcttcat tgatacaata
    97921 tgtaaggaaa gctgtaaaga aatgagacaa cagtacgaat cttatcaata tatagtaaaa
    97981 gcctctaaaa tcctagatac taaaagatat tctagtatta gtatgattaa tttaaaatac
    98041 gctttaatga gaattgataa tgaattagat gtagatagta atttaagtta tatatttgat
    98101 aattataata taactgaacc atgttttgtt gatgatattg aatatctaat tgatacattt
    98161 gtgataaata aagcaactct attaaataga ttaggagttg aggcatttaa cagaggtcta
    98221 ggagatttta gtataaacat gtttatgaca gtattagaga tggatagaga tgatattgac
    98281 tcaatatata atataacaag tgtattatgt gaattagaag aatttgatac tgcttataat
    98341 ttaattaaaa atagtagcga aaaagtacag agtgaaagtg atatacaaga gatactttgt
    98401 tttattgagg ggaagaaata tgaataatga taagatatgt tttataacct gtgtaaatga
    98461 tgaaaggctt tatgaagaat gtcttgtata tataaatagc ctagacattc ctaaaaactt
    98521 tagtatagaa acagtagctt taagaggagc cgattctatt gcctctgctt ataataaagc
    98581 tatgagagaa acagattcta agtataaggt atacttacat caagatactt ttataattaa
    98641 taaaaatttc atacatgata ttttagagat atttaaaaaa aatacagatg tcggaatgat
    98701 tggtgtagct ggagtaaaag atatgcctgt gaatggaatt tggtgggatt ctgataaaaa
    98761 agcagggaaa gtatatgata gtcatacagg taaaatggat atttatgaat ttagtaactt
    98821 tgaagaatgt tttaatgaag ttatggctat agatggatta attatgatta ctcaatatga
    98881 tgtattttgg agagaggata agtttgatgg gtggcatttt tatgatttgt cacagagtat
    98941 ggagtttaga caaaataaat acaaagttat tgtaccaaaa caaaataagc cttggtgtat
    99001 gcatgattct ggagtagtaa atataaataa tggatatgat gaatatagga taaaatttgt
    99061 aaaagagtac ataaatcttg atttatatag agaaaatttt tatgaatttg ataagaagaa
    99121 agcaagtacc atacttaaga gtaataagca tgtaatggat tgtatgaaag aggagcttac
    99181 agaacaatta agattaaaga attacaagga tgttttaggt attgtttcta aaattgctca
    99241 tttttctgtt tttaatcata ctggtttgta ttcttgtgaa gaatgtgaga gagcattgct
    99301 agaatgtgca aataatttac cagaaataga aaatacgaaa ttatttacaa aaaaagattt
    99361 aaaaagaaga aaagtattac atgttttaag tgaaggatat tcaacaggag gtcatacaag
    99421 actagttaaa aattggattg aaattgacaa agactctgtt cattcagttg taactacatg
    99481 gcaatcagat acactgccag actggttatt aaaagcaata aatgatagtg gtggcgaagt
    99541 tatatctttg gatttaattt cagatgatta tttaaaaaga gctgtagctt tgaggaaaat
    99601 agcttatgac tgggctgata tagttatttt atatgttcat atgtgggata caatacctgt
    99661 tgttgctttt ggagttgatg ggaaaatacc tattttacat gttaatcact atgatagtac
    99721 tttttggtta gggacaagta ttgcagatat tgtcattgat tttagcgaaa ctagtcaatt
    99781 aattacatta gataaaagag gcatagataa atctgaaata ttaccaatgc cattaaaaga
    99841 aaaagaagta ttttcaaaat ctgaagttag aaaacgatat aatttagagg atgatgtgac
    99901 aataatattg actattgcta gtgaaagaaa atacaatagt gtaaatgata ttaattactt
    99961 taaaattgct aaaacattga ttgaaaatac agataataca attattattg ttgtaggagt
   100021 tgatacagag aatctctatt ggaaaacttt aagtaatgtt acagataata gagttatatg
   100081 ttttggaaca acagcaaata tagatgattt ttataagatt tcggatatat acctagagtc
   100141 tttcatggta ggaagtcata cttcaaaatt agatgcaatt ttatatgatt taattcctgt
   100201 taagtttaaa aatgaagttt caccaatttt tacaaatatg tggaatttta tagataagtt
   100261 tgattataag aatataaaag aggttataga catgataaga aggtacaata ctagtgaatt
   100321 tgacagggat aagataaaag caaaacaatc ggaaataaaa cattttgtta tagataaaca
   100381 ttgtattgaa ataaaaaact atatagacaa aatatataat gaagttaatc atcataaagt
   100441 taagtatgat ttatataaaa atgatgaaat cgaggactat cagctttttg tagcattata
   100501 tggctatatg gtaaaaaata aaaacatgtc ataggtggta aaatgaacaa tattcatatc
   100561 aataaatttg aaaaaagctg tgaaaaaaac tgggattatt ttgtagaaaa taaatctata
   100621 aatggtacat ttctgcaaac tagaaatttc cttaattatc atgaggaggg aaaattcact
   100681 gaccactcat taataatatg taaaggtgaa gaaatactag cagtcgtacc tgcatgtgaa
   100741 acttatgaag atggtgaaag aatatttttt tctcatttag ggagtacttt tggtggcatt
   100801 ataataagaa gtggttttaa tgatattagg catgtaaatg ccattacaaa taagttagaa
   100861 atatatttac aggaacaaaa tttcgataaa gtatatttaa aaaatacatc aagaatattt
   100921 tgtaaagagg atacttcatt actagaatat tttttattta agaataatta catgttttat
   100981 gatgaattaa gtatgttttt agaattaagt aagtataaag aagatatatt agccaatttt
   101041 aaatacagta aaagaagaga ttttaaatat tctttgaaga ataatcttac ctttaaaaga
   101101 ctgtatagtg atgaagatat agtttgtttt tttaatttac tttctaattg tttagatagt
   101161 aaaggagcta aagtaataca ttcagtagaa gaacttttgg agtttaaaaa taatagatta
   101221 aaagatattg tagaatttta tgcagtatat attgatgaca ttatgatttg tgggagcatg
   101281 gtatttaact ttcaagaaag agtttatcat actcaatatc tagcatcaaa ttcgacatat
   101341 aataaatatt atccaatgat atttttatac tataatctaa taaaagatgc tttagagaga
   101401 aattttaagt atctttcttt tggaattagc actctaaata gaggcaaata cttagatgag
   101461 ggtttagcta catttaaaga aggttttggt tcaagtgcaa tttgtaacag aacatactat
   101521 aaaaatataa ataagtgaga atcatgtttt atagagtttt tagagtatag taaatatcta
   101581 gtactataat attacataaa aataattagt ttataaagaa ggtttgtata tgaaaagatt
   101641 aatgatttta ggctcaatta agtattttga gaatattgtt atgtcagcta aaagagaggg
   101701 aatatacaca attgtttgtg ataatagaat tgatactcct gcgaaaaaga tttgtgatga
   101761 agcaatagat gttgatgtat ttgattttga taaaataaag aatatagcta tagataaaaa
   101821 gatagatgga attttaactg gatttacaga ttctttaatg aagccatatg tttatattgc
   101881 aaatgaacta aatttgccat gtgtgatttc ttgcaatcaa cttgaatctg taactaataa
   101941 ggctgttatg aaaaattatt ttaaaaataa tggaatacct acaactgatt attgtattat
   102001 tgaaagtttg aaagatttag aaaaaataca aggattaaat tttccacttg taataaaacc
   102061 tgttgatggt tatggttcaa gaggtgtata ttttgtatca aacatagaag aattaataga
   102121 aaaatttgaa tattctaagg aagcctcgca agatggacaa gtaataattg aggaatttta
   102181 tgaaagtgag gaaatacaag gactagcttg ggttcataat ggagagtcac atgtatttta
   102241 tattggagat agagagcttg taaatataca tacaggaaga gctggaaaac cagatagatt
   102301 aatttatcca tcaaagtatt gttttcaata tgaagaagaa ataaaatcca tatatcaaaa
   102361 tataacgcag gcttttggca taaaaaatgg acctctttat gtacaaatgt tagtgggagc
   102421 atatggaata aaggtatctg aagtaatgcc aagattacct ggaggttgtg actatatggc
   102481 tatttctcaa ataacagatt tagacatagg aagtttattt gcaaacttta gtgtgaataa
   102541 tgaagtaaat tttgatgaaa taaagaaata taatatgcat ctatcaaaat gtgtatatgc
   102601 attaccaata tacataagac ctggcacaat aaaaaagata aataatatag ataaaataga
   102661 aaacttagat tatgtcactc aatttctatt actagtaaaa gaaggagata caataggatt
   102721 atatgaagat gagagacagg attgtggaag agtttatgga gtagcaaata atgtatttga
   102781 tgcaaatata aagaagaaat gtattcatga aatgatagaa atacttgatg aaaataatga
   102841 aaatatgata gaaaattttt aaataaggga gtatgataga tatgaagcta ataactcatg
   102901 aacaaattat gtcattaaac atttctcaga aacaaggata cgagtggata aaagaatcct
   102961 ttttaacaaa aaaagattgt caattaccac caaaaataag catggtagaa gaagggcatg
   103021 tattttacaa tgtaatgccg tccctaaatc ataatcataa gattggtgga ataaaaatgg
   103081 ttacaagatt gccagggaga aatccaagtt taaattcaga gatatttcta tataatatgg
   103141 aagatgctaa attaaaggct attttagatg gcaattatat tacagctttt aggactgctg
   103201 ctgttgctgc cttggctatc gatacatttg ctaaaaaaga ttttaatact attgctatta
   103261 tgggtttagg tgtaactgct tctgctataa tgaatatgct ttcatatact cttaaagata
   103321 aaaatataaa tataaagtta cttaaatata aagaccaagc agagtcgttt gtaaaaaagt
   103381 atgaaaaaaa tgaacaattt agttttgaaa tatgtgacac acatgaagaa cttattgtag
   103441 attcagatgt agttatttct actgtgacat atacagatga atatttatca gaatttaaat
   103501 ggtttaaaaa aggtgcttta ttattacctg tacatgttat gggatttgga aatgttgatt
   103561 atctatttga taaagtatat ttggatgatt ataatcattt gaaacatcta gaaaatatag
   103621 atagatataa atattcttgt gaattttatg atgttttaag taaacaagct aaaggaagag
   103681 aaaatgatga tgagagaata atatcttaca atataggttt gtcaatacat gatatattat
   103741 ttgcaaataa aatttacgaa ttgtgtgaaa cactaagctg tgaagaaata gaattaaaag
   103801 aaccaaaaga aaaatattgg atatagttta tttcattcat atttacaata gtttattgta
   103861 aatatgaata tgaagtaata tattgttaga aaattagcat gaataggata gataaattta
   103921 tggataaata taatttaatt aggttcgtat ctattggaaa cgaatatata ggaaatttag
   103981 ttgcattaga atcaaataaa gcaatacctt ttgatataaa gagagtttat tacatatatg
   104041 atgtaccaaa caatgtaaag agaggatttc atgcacacaa aaacttggaa caagtactag
   104101 tttgcctaaa tggaagtgtg aagataaaat gttatgatgg tgtaaaagag actatattta
   104161 atttacataa aaatgatgtt ggattatata taggaacggg agtgtggcat gagatgtttg
   104221 attttgatga aaaaactgtt ttaatttcta tagcatctga acattataat gaagaagatt
   104281 atattagaga ctataaagaa tttttaaagt atttaaataa tatgtagtta ttatacagtt
   104341 agtgatgtat tttcttaatt aaataaattt aagatagcca catagagaat agatagatta
   104401 ggatgtgaat ttattgttgg ttaaatttaa taatttatta aaacagttcc aaacccataa
   104461 agaagaatat gaacagaaga ttaaggatgt aatggaaagt ggatattata tccttggaaa
   104521 tgaagtaaag cattttgaag aagaatttgc taactatgta ggtagcaaat attgtgttgg
   104581 tttagccagt ggtttagatg cactgataat tgcttttaga gcattaggaa taagcgaagg
   104641 tgatgaagta atcgtgcaat caaatacata tattgctagt gttatgggaa tcagtataaa
   104701 tggagcaaca ccagtatttg tagaaccaaa tgaatattat aatatagatt catctaagat
   104761 agaagaaaag ataaatagca aaacaaaagc tatattagta gtgcatttat atggtcaagc
   104821 aagtaatatg aaagatatac aagaattatg tgataagtat aacttgtatt taattgaaga
   104881 ttgtgctcaa tctcatggag ctaaatatga tggaaaaatg acaggaacat ttggtgatat
   104941 aggttgtttt agtttttatc caagtaaaaa tttgggtgca tttggagatg caggagctat
   105001 agtaactagt aatgaggaaa tagctgataa agtgaaaatt cttagaaact atggctcaga
   105061 aaagcgatat tataataaat ttgtcggata taattcaaga ttggacgaaa ttcaggcagg
   105121 tttattaaga gtaaaactta aatatctaaa tgaaattgaa attgaaaaat caaaaatcgt
   105181 agatagatat cttaatgaaa ttaataatcc caaagtcata cttccaaaga tagaaaataa
   105241 ttgtactcat gtatggcatt tatttgtttt acaagttgaa aaacgagata catttatgga
   105301 atacttaaag aaaaatggta tagagtctat aatacattat ccgataccac cacatctatc
   105361 tgaagcatat gcttatttgg gatataaaaa ggggagtttt aatatagctg agaactattc
   105421 agataaagtt gttagtatac ctttatttat cggtatggaa gatgaagaag ttagttatat
   105481 aattaaaatt ataaatgaat attaaactac tcataataat atcaaaaata aattttttat
   105541 atatcattta tttaagtttc gttaattgac atttttaaat attgatatat tgtacaaata
   105601 aaattgaaat atatggaaaa atatagaatt aagatgagat ttgtcttata tttttataaa
   105661 ttaaaaatat tttcaaagag tttattataa aattctagag tatagtgttt ataatatttg
   105721 taattattgg taactaaata taaaatataa aatatttgat tataaacaaa aaagatattt
   105781 aaaaaatttg ttatttattg tatacttaag ttaaaactaa ataggcaaat ctagagaaat
   105841 ctagtgacgc aaagctatag ggactaaggt ttatatacat gaactatgtc agccagttgc
   105901 caaaaagagt cctaggtgta ttgtatacct aagaaaagtc tagaatgact gcctttttgg
   105961 cagtcatttt gttatgaaaa aatcacttta tttcagtaga aaatacctat aattaacata
   106021 ctttaccaaa ttataacata aaataaagaa aaattatctt aaaaagttac tattttacaa
   106081 aaaagagcaa cttttcgaag aaatatttaa atacatatta aaattttttt atattttcat
   106141 gggacttcat tgaaaaaata ttagttttct tactaaaatg atacattatt gtattaatgt
   106201 aatggaaatg cgattaattt aaatgaataa agaagtcatt ttttgtaata tagcaacttc
   106261 atttttttat taataagcaa aataaataaa atatattttg aggaggagtg agtgtgaata
   106321 catatgacat tataaaaatg ggattagatg caactaattt aagaagtcag acaatagcaa
   106381 ataatatagc aaatataaat actgaaggat ataagagaca ttatgtaact tttgaagaaa
   106441 cattaaatga tgctatgccc aaaatagaag aaaaaacaga taattctaaa ggattaagag
   106501 tggatggcaa taatgtagat atagaagaag aaaaagtaaa ccaagcaatg acaacattac
   106561 aatataatgc tttgataagt tttgcaaatg gaaaaatagc aatgactaaa tcaataataa
   106621 gtgggaggta attaaaaggt gagtgtgttc agtggaatga gaatatctgc tagtggatta
   106681 acagcagaaa gcttgaaaat ggatatcata tcgtccaatg tagctaatat aaatgccaca
   106741 agaggtccaa atggagaagc atataggaga aaagttgttt catttgaaga aaactatgat
   106801 aataaattag gtatgctagg agtaaaagtt acatctgttg aagatgataa atcacctctt
   106861 aaaaaagtat atgacccatc tcatccagat gcaaagccaa atggatatgt agaatatcca
   106921 aatgtaaata tattggtaga aatgacagat ttaataacag cttcacgagc atatgattct
   106981 aacgtagata cattgaatgc tcagaagtct atgatatcaa aagctttgga aataggaaag
   107041 tagggataaa ttatgccaat tacacaaatt aacaatttaa tgcaaggtgc aaagttagat
   107101 aatttgattg gagaaacaaa accattaact cttaataaag aagaaaaaaa gaattttgaa
   107161 gatgtaataa tagatactat agataaagtt aattttcaac aagtgacagc agatgatatg
   107221 aaagaaaaat ttataaaagg cgaagatgtt tctatgcatg aagttatgtt aataggtcaa
   107281 gaagcacagc tatctatgca atatttaata gaagttagaa ataagattca tgatgcatat
   107341 caagaaatga ataaggtaca aatttagcct tttgaacagg agtaataatc aatgatagcc
   107401 agttttaaaa ataagattaa agagcaagtt gctaaatcta ggacaaagat aagttctcta
   107461 aaaaagggaa ctaaaatagc attaggtata ggggttattg ctatatgttt agcgctagta
   107521 tttacagcaa tatctgcgag caaaaataag tatgcagtct tattttcaga actagatgtt
   107581 caagatgctg cagatatatc agcagaatta gagtctaaaa agatagatac taaggtaaag
   107641 ggaagtacga tttatgtacc tagaacagaa gttgataagt taaggctgga gttagcacca
   107701 agtcttacaa gtggttctaa aggatttgca ctaatggatg atagttcatc aataggactt
   107761 actgatgaag agtttcagat taagaagcaa agaatgatac aaggtgaaat agaaaaaaca
   107821 ataaagagtt ttccacaagt ggaagacact agagtacata taacatttgg agagtcatca
   107881 gtatttgaga aggaggctgt tccagggagt gcagcagttt atttgatgct aaaaccaggg
   107941 acgactttag aaaaaaacca aataaagtct gttatggcac ttatatcagg aagcgttaca
   108001 aatataccag agaaaaatgt tcaggttatt gataacaaaa tgaatttatt atctgaaggt
   108061 attttggagg atgaaaatgt taatgaaaat aatcaaccaa taaatagtgg cattagtgtt
   108121 gataaaaata aggcatctga acaagcattg aataaacaac tagaaaagtc tattttagaa
   108181 atactagaac caatatttgg taagggaaag gtgaaagcta cagtaaatgc tgatttaagt
   108241 tttgatacag ctgaaaaaac tgagataaaa attgaccctg ataaagttgc aataaaagag
   108301 acaaggtcga aaaattcatc taaatctgct acaaataatg ttcaaggtgt agatgctaac
   108361 atgaataacc aaggaaataa caatggtact aatacagaag atagtttaga tgagagtttt
   108421 gagtatgaaa caggtaagat tgaaactcat actatagttg cgcctggaga acttaataga
   108481 ttgacagctt ctgttgcaat agatggaaaa atagctaaag gtgttcaagc tgatgtagag
   108541 gatattgtta ataatgctat aggtatggat ggagcgaggg gagatactct tagcgttgtt
   108601 tcaatggtat ttgacccaga aggtaagaaa gaggctaaac aagagctgga agagattaaa
   108661 aaagaaggat ttaaaaagaa cataataaaa gcagttattg gagtagtggc agtagtagca
   108721 attggagcta ttggatactt gatatataag aaaagaagtg aacgagaaga tatggattat
   108781 gaagatgaag attatatttc taaatctgat tctgttgata gaaaagataa tcctctatta
   108841 ggagatgacc cagaactgac attagaggaa gctgttaaaa tgtatgcaga agaaaagcca
   108901 gaccaagtaa cagagataat aaaaacttgg ttaaatgagt aagggggata gaaagtgtcc
   108961 acggaaatta caaatgttaa tgcgtttgac ttaagtgata taaatgagag tgataagaaa
   109021 gagaagatag aaggtgaggg tttaaaaaaa gctgctgtat tattaatgac attaggacca
   109081 aatgtttcta gtgatataat aaaaagcttg cctgataaac aagttcaaaa aataggtttg
   109141 gaaattgcaa atatttcttc aatagcttca aaagaaagaa gagaaatctt aaaagagttt
   109201 gtagaaataa atagggcaaa agattatgtt atagaaggtg ggcttgaata tgcaagagag
   109261 ttgttaagca atgctttagg aaatgccaaa gcaaacaaat tacttgaagg tatatcaata
   109321 aatacaagca caaagccttt taaacatatt ataaaactag atgtaaagaa aatattagaa
   109381 atacttagga atgaaagtgc acaaactata gccgttttac ttgcacatat ggagccagaa
   109441 aatggagcag aagttttatc atacttagat tttgatttac aaaatgaagt agctatgagg
   109501 ataagctcaa tgggttcaat atctccagaa gtaataaaag taattgaaag ttcattagaa
   109561 gataaattac actcaatgag tggtgatgat tttaaggatt atggaggagt gtctacctta
   109621 gttcaaatat tgattaattc tgatagaaaa acagaaaaga atattttggg aactattgaa
   109681 gaacaagacc cggatttagc agctcaaatt aaatctcata tatttgtctt tgaagatatt
   109741 gtcaagttag atgatataag tatacaaaaa gtgttaaaag aagtgactat gaaagattta
   109801 gtatatgcct taaaaggtgt ggatgatgag atttcagatg ctatatatag aaatcaatct
   109861 tctagggcag cagaggcact tagagaagaa atggaaatgg ttggtgtcat aaaagttaca
   109921 caggttgagg ctgctcaaca aaagatagca aatatagtaa gaaaacttga aagagaaggt
   109981 gccataacta ttgtaaggaa ttttggtggt gactttgttg aataataaga ttattaaaag
   110041 taaaaaagca ttatataaag gagtgctaga tttaaccata atagataaag ttagagtggg
   110101 agaatcaaat gtaaataaag aaaatgattg tagatttagg gatgaggtaa taaaagaagc
   110161 tatagaatct gctgagataa aaaagaatga gatattagaa gaagcaaaaa tgaatgcaca
   110221 aaatatagaa aagcaagcat atgaaaaagg gtatagtcaa ggtcaaaaaa atggatatga
   110281 agatggatat aaagagtcat ataatgaata tacccaaaaa gctaaagatg aagcagattt
   110341 tataaaaaat caggcagact taatactatt acaagctaat gagaagatga ctgagtacat
   110401 aaaagaaaaa aataaagaga ttgtaagact tgctattaat atggctagtt ctgttctaaa
   110461 aaagcatttc gaagatgaag aatctatgag tgatttgtta aagcaaatta ttcaagatta
   110521 tgaaggaagt agttcattta tagtaagatg taattctttc tataaagata atatagagaa
   110581 agagtttgaa ttattcaaag aagaaacatc actaaaatca agtgtatttg ttattgcaga
   110641 tgatagtata gataaaggca atgctatcat ccaaaaggaa aatggaagaa taatagttgg
   110701 tatcgattgt gctatggaaa aactaaaaga agaattgctt ggtgaataaa gtatgtataa
   110761 aactgatata tctatagatt ttgacaaaat aaataagaaa atagaaaatt tagaactcac
   110821 tatatcagaa ggtagagtca aaaagataat aggacttact gtagaagttg aaggaataaa
   110881 agcttttgtt ggagagttat gtgttatata caatcaagtc aataaaccag tgaattgtga
   110941 agtagtgggt tttaaagata aagaagtcat attaatggcg ttgggagagt taacattgat
   111001 agctcctggt tgtaaagtta tttctaaggg gataccttta agtgttatgt gtagcgataa
   111061 tttactaggc aaagtacttg atggtcttgg aaatcctata gataactcag atgctgtttt
   111121 aggagataga tacaacttga acaatgaacc tcctgatcca atgaagagaa aaaagatacg
   111181 aaatataatg gaaacaggtg taagagcaat agatgcattt actacttgtg gtgaaggaca
   111241 gagaataggg atatttgcag gaagtggagt aggtaaaagt acgactctag gtatgattgc
   111301 taggaatgca aaagcagatg taaatgtaat tgcccttatt ggagaaagag gaagagaagt
   111361 attagatttt attgataaag atttaggtga agagggaatg aaaaaatctg ttgttgtata
   111421 tgcaacatca gataaagctc ctttggttag gctaaaaggt gctcttactg ctactgcaat
   111481 agcagagtat tttagagacc agggcaaaaa agtaatactt atgatggact cggtaactag
   111541 atttgctatg gcacaaagag aagttggtgt agcaatagga gagccaccag ctcaaaaagg
   111601 atatacacca tctgtgtttg ctattttacc aaaacttatg gagagaacag ggacatcaga
   111661 taaaggttct ataactgcat tttatacagt attagttgat ggagatgact ttaatgagcc
   111721 aatagcagat acaacaagag ggatacttga tggtcatata gttttatcta gagacttggc
   111781 aaataagaat cattatcctt ctatagatgt attgaacagt ttaagcagac ttatgaatga
   111841 gattgcttca aaagaagaca taaaaatagc atcttttgcg agagatatgc ttgctgagta
   111901 tagagaagca gaagatttga taaatatagg tgcatatgct tcaggtacaa acaaaaaaat
   111961 agatgaagca atctactatc atgagcatat tattaatttt ttaaaacaag gaataaatga
   112021 aaagagctct tttaatgaaa ctataagtag tttaagagga atctttgaat aaacaattta
   112081 aaaaaatatt tgaataggtt gtgatggaat tggataaaaa ttttaagttt agattacaga
   112141 aagttttaga cttaaaaata aaagatgaag aagagataaa aatggaattt gctaagattc
   112201 aacaaaaaaa aatagatata gaaactaatt tagaaaactt agaaagtaat tacagcaaat
   112261 attctatagg taaaaataat gatagtgttc aaaatcaaaa aataactatt aactatttgc
   112321 tagctttaaa caactctata atggatttat cagaaaaact ggataagtcg acaaatgaac
   112381 ttgaaaaagc tagaaaacag cttataagca aacagataga gagaaagtca ttagaaaaat
   112441 taaaagaaaa aaaatatgga cagtattata aagaagaaca gttaaaagaa caaagcacta
   112501 atgatgagtt tgcaagcatg agttatttga gaaatagaca agttctataa aatagtagga
   112561 agtgaggata ttattgtatg aagatacaag cagattctta taatattatt aaagatattg
   112621 ggaatagaaa aaactcatct aagaataaaa atataaaaaa tgataaattt gaagataatc
   112681 tatataagac aacagaccat aaaaaggtta aagatagaag agaaacaagt aagcaaaatg
   112741 ttagctcaga tagaccggaa aatagtgata atgagtgtca tttagatgaa gataaaagta
   112801 atcacttaga agatgaaaat acatatgaaa aagattgtag taataataat gaagctttgc
   112861 agcaattact gaatctttta aaagagaatt ataaaaaaga taaagatata aacactatat
   112921 tgaataatat aaaaaaacta agtatatcag atgaattaaa acaagaactt aagcttaata
   112981 aaaatatatt aaataagatt gcaaatcaaa attcagagct aaataaagct aatataaata
   113041 actctaatga tatagaaaat ttagacatag ttaaattaag agaacttttg gaggataatg
   113101 ctaataaaga tattgaagta attactaaaa ctacagaaaa tgatactaaa aatatagatt
   113161 tgtatagttt tgatagcaat agaatggata atcttaactc aaataaacag aaagatgata
   113221 gctctgatat tttggaaaaa ctagcagggg taaatggaaa taagagtggg aattttggac
   113281 aagtaataaa taaaaatgtt gatatgaata aaattaaaaa tgataatgtc aatttaaaac
   113341 agatagaatc aaatgtaatg gatgactcta taaaagctat taagcatatg aaaacaaatg
   113401 atatacaaga attgacaatt aaattaagac caaaagaatt aggagatatg aatatacaat
   113461 tgttaaaaga tggtgaaagt atgagagctg ttgtgactgt tttcaataaa gatgtctttg
   113521 actctataaa taaaaacata gcagatttaa agcaacatct tgaacttact aatgtaaata
   113581 taaaagatgt atcagtgcaa atgcacagcg ataatacaaa tacatctgat acctttgata
   113641 aagcatttga acaacagaat agacaaaata accaagaaaa catgagtaag aagaatacaa
   113701 atgataagca taataatgta gtcatagaag atgacattaa agaaaatact attgatgatg
   113761 atagagtaga tttactagct tagtaagggg gaagtattgc atgtacggaa tagcaacggc
   113821 tttggcagga actcagggaa actataggtc aaataactta agccaacttg aaagaaatat
   113881 taatgatatt gccaataaac aagttagaag caaaggaaat cagacagtaa cagacaatgg
   113941 gactccaatt ataggacaag gtgatgatgc tgataaagac ttgtttatga agatacttgt
   114001 ggcacagatg ggtaatcaag acccaatgaa tccgcaagac ccaacagaat atgtgtcaca
   114061 attagcacag tttgcaactt tagaaaagat gtcagctatg aatgagaagc tagatgtact
   114121 tttagcctta agtaattcca ctctaataaa ctctgcttta agtatggcaa catcattaat
   114181 tggtaaagaa gtagaagtat ctggggaaga gaaagaagat gaaaacattg taggagtagt
   114241 aaagtccaca tatataaaag atggggaagt acacttagaa ttagaagtag atggaagtga
   114301 caaaactgta ggtgttaaat atgaaaaatt acttaaaata ggagaggtag atgaaaattc
   114361 aggagaagaa aatgattctt cagaacacga atctccagaa gaagcataat attaaatgag
   114421 aaaagaggta aattcatgat aaaagcaatg tattcaggtg taagtggaat gaaagcaaat
   114481 caaacaaaat tagatgtaat aggtaacaat gtagccaacg ctggaactac ttcttttaag
   114541 aaaagttcag ctagaataac agattcattt tatcaaactg tactatatgc aagtgctcca
   114601 acagctgcat taggaggaac aaacttagga caagtaggtg taggtagtaa gatatcaagt
   114661 ataaataaag atatggtaca aggaaatgta caaccaacta atagaccatc tgatttaatg
   114721 atagatggag atggatatct tccagtagta agacaaggaa cagttatgta tacgagagat
   114781 ggttctttta atttagatac aggatttaaa gcagctgatg gtgctttgaa gaatattaaa
   114841 ggtggaagac ttgtaaatgg tgatggatat atgttacaag gtatgattta tgatggggaa
   114901 tataaagctg atactggaga atttgttaaa aagggtgatg ctaaaggaaa agagcctatt
   114961 gtaataccac ttcaaagtat aagtcctaag gatggaacag ttcaaaatgt actagagtat
   115021 aatatatcaa aggatggaac agtagaattt ttattgagtg atggtcaaag aactcaattt
   115081 gtctatgata tacctgatgg tgctaaggta ggagatacac ctgctggaat agataaatta
   115141 aaaggtacaa tacaaaaagt gcaaacatat gcattccaaa atccagcagg actagatgca
   115201 gaaggaggaa acttgtttaa accatcagca aactcaggag acccacaaat agcaggagct
   115261 acaggcacaa taatacaagg ggcaatagaa gcttccaatg tagatatagc agaagaattt
   115321 acagaaatga taatagcaag taggtctttc caagcaaaca gtaaaataat atcgacatca
   115381 gacgagatac ttcaagaaat aataaatctt aagagatagt aggtacatat tatgataaga
   115441 gtaacggatt taaacggaag aaaatacata ttaaattcag accttatagt gaggattgat
   115501 tctgtaccag aaagtaggat tctccttaca acaggagaaa aaaaccttgt aaaagagtcg
   115561 gtagatgaga tagtagataa agtaataaag tataaaagaa aaataaatgt aggttatatt
   115621 aggagcgaaa aataatgaaa aaaacagatt cactgacatt tattggacta atagtatcta
   115681 cagtattagt tttagttggt gccgcaaaag gaagtagttc agggttaaag aatttttttg
   115741 atgtttcatc aatattaatc acagtgcttg gttcatttgg agctctaatg attacattta
   115801 ctatagatga tataaaactt ataaaaaatg cattacaata ctcatttaag acaatgagtg
   115861 tatcaaagtt agatttacta gaacaattta aaacactttc taaaaaagct agaaaagaag
   115921 gtcttttatc aatagagagt gatgtaatgg gaatagaaga tccatttatg aagaaagggt
   115981 tagagctgtg tattgatgga ttggaaatca atgagataag gtccatctta gaactagaga
   116041 tagattctgt tgaagataca aataacagat attctaaact atttaaaact tggggaacct
   116101 ttgcacctgc ttttgggatg ttgggaacac taataggttt aatacaaatg ttagctgacc
   116161 ttacatctcc agatttaata gcatctggca tgggaaaggc attaattaca acgttttatg
   116221 gttctttact tgccaatatc gctttgaacc caattgcata taatatagat gagaagactg
   116281 aaaaagaaat ttatgtaaag gaaatgatgt tggaaggtat aataagcata caatctgggg
   116341 agagcagtat agtagttgag gaacgtttag ccacatacct ttcaaacaat gagaagttag
   116401 aaattatgaa atccaataaa aatacagaaa gagcaatgag caatggcgcg taaaaaaaat
   116461 aagaaaaagg atgagataaa tccagatgca tggctggcta cttatgcaga tactataaca
   116521 ctgattctta catttttcgt attattgtat gcaacatcag ttgtagatat ggaaaaattt
   116581 aaaaacatag cagatgcgtt aaaaggtcag ttttctggga caagtatatt tagtacgggt
   116641 tcaagtacaa gtgagaaatc tccaatagac agtgttttag tggataaaaa tgataaatca
   116701 aatttagaac aggatttaaa agataaagtt aataattcta acttacaaaa tagtgtaaca
   116761 gtcaaagatg atagtagagg gattttacta gagttagatg attcaatttt atttgactct
   116821 gggatttctg agttaaaagt agatagtaaa gctactctta ataaagtata tgacatgata
   116881 aagatgatga aaaataagat agttatagaa ggccatactg ataatgtacc tgtaaaatca
   116941 agtacacatg aatccaattg ggatttatct tctagtagag cagtaagtgt tgtaagatac
   117001 tttgtagaag aaaagggcat ggaccctaga ctattttcgg caacaggatg tggagagtat
   117061 caacctttgg tttcaaatga aacagcaaag ggaagggctg agaatagaag agttaatata
   117121 cttataacta ttgactagga ggaagaggtt tgttcaaaaa taaaaaaatt attataatta
   117181 ttttgatact gattattttc tcagcgggag caggtttttt tatattagga gaaggtggaa
   117241 ataaacaagt tgacaagatt gcaggtttgt ttattccaac aggaaaaggt aaagatgaag
   117301 taaagaccga aaatcttgac ttagaagaga tggtattaaa gttagctgat gaaggtgtaa
   117361 gatatttaaa agtatcaata actgtatctt atgattcttc atataaagat atagaaaaaa
   117421 atacgccttt aattagggat aatattataa attgttttat ggcaaaaagg gcagatgatt
   117481 ttactgctga taatttaaag aacataaaag aagaaattaa aaatacatta aatatacaac
   117541 taggtgaaaa tgtaattcaa aatatatatt tcacaaatat agtagtgcaa taaaaggatg
   117601 gtaagacatg atactttatt tactaaaaat attaatatgt atcccaataa ttttaatatt
   117661 gatagtctta tctttaaaaa ttagccaagg aactttatta aaaaaatata atgataaata
   117721 tgtaaaaata ctagatattg taaatataag taaaaacaat agcataataa ttttaaaaat
   117781 aggtgaagaa ggatgcatta tggcatcttc ttcttctagc atgagtaaaa taaaagattt
   117841 gaccaaagaa gaagtattaa aaatagaaaa cgacattaaa gaaagaaatt ttaaaattca
   117901 agattttaaa atggaaagaa ttaaaaagaa atatgatttc agtagatata ttggaaaatt
   117961 tacaaaaaag gaagataagt aaatggaact attatcaaaa ttacctttgg ctgatgtacc
   118021 atatacaagt tcaatgcaat tgtttttatt tctaactgca ttaatgtttt taccatttgt
   118081 aatgttcatg atgacaagct ttgtcagaat agttataagt ttatcatttt tgaaatcagc
   118141 attaggagca cagcaagcaa ttccaagtca aattttggta ggacttgcaa tagtattgac
   118201 aatatttata atgagaccag tattaaatga gataaacgaa aaggcattac aaccatatat
   118261 gaaagaagaa gttactatgg aagaagctat gaaggaagca gaaggaccta ttaaagagtt
   118321 tttattaaca caaaccagac agacagattt agatttattt gtagaacagg ctggtttaaa
   118381 agaaaagaaa ttaactcgtg aaaatatacc actatctgtt gtagttccag catttgctat
   118441 aagcgaacta aaaactgctt ttcaaatagg ttttttaata tatataccat ttttgataat
   118501 agaccttgtt gtggcaagtg ttttgatgtc tatgggtatg tttatgttgc ctccagtcat
   118561 gatatcatta ccatttaagt tattattatt tgtaatggtg gatggatgga acttgatagt
   118621 aaaaacattg atattgggat ttggatagga gaaaaatagt atgagtgaat ttatgataat
   118681 gagtgttctt aaaaatggca tgtttacagg agctatgatt gcagctccag tactcattgt
   118741 ttctcttgta gttgggcttt taataagtgt gtttcaagct acaactcaaa tccaggagca
   118801 aacattgact tttgtaccaa aactaatagc tattctttta gtagtagcta tcggtggaag
   118861 ctggatgtta catactctta ttagttttac ttctgagata ttcaatatga tatctcttat
   118921 aactaaataa gtaggataca tatgattttt gtatttatta gaatagtagc attctttgga
   118981 acactaagaa tactatttcc agctggtaca cctgctttat ttaagtcact ctttgcaatc
   119041 attatatcaa tattgatttc aagtactatg caaattgaat atgcaacaaa tatagacaac
   119101 attgtattgt ttaccttata tagtgtaaat gagaccataa ctgggattat gcttggatat
   119161 ataaccaacc tatgttttta tagtatcaga atggcgggtt ctatgatgga ccaacagatg
   119221 ggattatcaa tgattaatat gtttgaccca aattcaatga ctcagacaac tttaattgat
   119281 aatcttatga actggacagc acttatgata ttttttaaca tggatggtca tcatgtttta
   119341 attagaggta taaggtatag ttttgagtta attccaatag gaaaaccatt tgtagataat
   119401 aacatagatt atataataaa catatttgtg cagtgctttt taactggatt caaaatagca
   119461 atacctattg tactttgtct gcttatggca gattttattt tagggcttat atcaagaagt
   119521 gtacctcaat taaatgtaat gatagttggt atgccattaa aaatattggt tggtattgca
   119581 ttatttatca tatcaatacc tttaattgtc aatcaaataa gtcatttatt aagtcaaata
   119641 ccaaagatgt atgagggaac ttttgcacta gctcctatgt tttttatggg ttcagcagat
   119701 aaaacagaag aagctactcc aaagaaaaag ggagaacaaa gaaagaaagg taatatagca
   119761 aagagtagag aattacccgt tgcaatgact ctacttgcat tcaccttatt agtacctaca
   119821 ttattttcat atgtagtaga tacacttaaa tcttcgctta attatttttt gagtctagat
   119881 ttttatatga acataaatta ttcaaaccta gagaaattag ttatagcagg attaatggat
   119941 ttttttaaga tatttttacc aatagctatt ccctttttag ttttaggcat aatagcaaac
   120001 ctatttcagg tgggaatact gtttactggt gaaactttaa aaccaaattt atcaaaatta
   120061 aatccaatta gtggattcaa aaacatgttt tctatgagaa gtttgtcaac cttaataaag
   120121 gatacagcga ttatatctat tttggcttac ataggatata cattcttcca agataattat
   120181 ttagatatat taaagttagg taacatatac ctaccaactt taatgtacac agttaaagac
   120241 ttagtatatt caatattgag taagatttgt gtagctatga tagctatagc agttgcagat
   120301 tatgtttatc aaagatacag tcataaaaag caactgagaa tgacaaaaca agaagttaaa
   120361 gatgaatata aaaactcaga aggagaccca gaagtaaaag ctaagataaa acaaaaacaa
   120421 agacaaattt cgtctcaaag gacaatgcaa gcagtaccaa gtgctactgt aatagtaacc
   120481 aatccaaccc acttatctat agcagtgaga tatgaaaaag ggaaagacca agctccagta
   120541 gtggtggcaa aaggtgcaga ttatttagct tttaaaataa gggaaattgc aaagggaaat
   120601 gacataccta taatagaaaa taaacctatt gctaggttgt tatataagca agtagaaata
   120661 gaccaagaaa ttccagagga catgtatcaa gcttttgcag agatattagt agcagtatat
   120721 aaaatcaaaa atagatacaa agtccccaaa aggtaggata agtaatgaat aagtttaatt
   120781 taaaggaaaa tatggacgta atagtggcat ttggtgttgt agggattgtt cttatgatga
   120841 tagtgccgtt acctacattt atattagata ttttactggc aattaacata agtttatctg
   120901 tgctaatttt actaatgaca ctatttacaa caaatgtact tgatttatct atatttccaa
   120961 cagtgttact tgtgacaaca ctatttagat tgggattaaa tctttcatca actagattga
   121021 ttttaacaca gggatatgca ggtgaagtta tagaggcatt tggaagtttt gttgtaggtg
   121081 gaaattacgt agtaggaata attatattct taattatatt aattgttcaa tttgttgtta
   121141 taaccaatgg ttctggaaga gtatctgaag taacagctag atttacgtta gatgccatgc
   121201 caggtaagca gatgagtata gatgcagatt taaatgcagg agttatagat gacaaaactg
   121261 ctagaaaaag aagaaaagag cttcagcaag aagcagattt ttatggctct atggatggag
   121321 caaataagtt tgtaaaggga gatgccatag caggtcttat agtaacagca ataaacataa
   121381 taggtggaat tgtaatagga gctgtaatgc tgaatatgac tcttatgggt gcagcacaga
   121441 catatgtaag acttactata ggggatggtc ttgtaagcca gatacctgct ctattaatat
   121501 ctacatcagc aggtataatc gtaacaagag cttctactga tgaaaacttt ggtggattag
   121561 taggtaaaca gttaacagca ataccaaaag cagtaatgat gactggctgt gttctaatcg
   121621 tacttggtat gatgcctgga ttacctaaac cagcattttt ttcactaggt ataggtgcta
   121681 tagcagcagg ttacttttta ggaagagaaa agaaagatac tttagaagac ttggagtttg
   121741 aaaaacctga tatggtaaat ccagataaaa atgaagtaga agatgtaaca aacttaataa
   121801 atgtagaatc aatagaagta gaaattggat atggtttaat atctttagct gatgaatcag
   121861 caggaggaga tttacttcag agaatagcat caataagaag acaatgtgca atagacatgg
   121921 gtatagtcgt acaacctata agaataagag ataatttaca gttaaatcca aaccaataca
   121981 atataaaaat aaaagggaat gtagttggtg ggtatgagat aatgcctaat atggttttat
   122041 gtatggatcc tatgaatcaa ggatttagta tatttggaat aaagacaatt gagcctactt
   122101 ttggaataga ggcactttgg atagaaagtg acaaggtaga agatgcagag ctaaagggtt
   122161 atacagttgt agattcatcc acaatactta taactcactt actagatata ataaaatcaa
   122221 atgcacacga attactggga agacaagaag ttaagactat tatagatgca gcaagagaaa
   122281 attatagtgc tgtagtagat gaattgatac cagatttaat gacacttggt gaaattcaaa
   122341 aagtacttaa aaatctgtta agagaaaaag taaatataaa ggatagagtt acaatacttg
   122401 agacacttgc agaccagtct agaaatacaa aagatataga gcttcttact gaatatgtaa
   122461 gaatagcttt ggctagaagt atttgtaata atttagttga tgaagataag gcaattgtag
   122521 tggctacatt gtctccagaa actgaagaat tggtatctaa taatttacaa aggtctgtaa
   122581 atggaactta tccagcagtt gacccagaaa atacaaataa aatatttgag agtatacaag
   122641 aagtaatgaa caatgtatat ttcaatcata atataccagt aatagtagta tcaccaaaga
   122701 taagagctcc atttagaaaa ttagttgaaa ttgtatatcc taatttgact gtattatcat
   122761 taaatgaaat acctaacgat attaaaatca aagcagaagg tgtggtgagc atatatgatg
   122821 acgaaaaagt atacagctaa cacaattcaa gatgctatga atctagccaa aatggaattg
   122881 ggtgacaata ttacattaat agataaaaaa gaggtaagaa aatctggaat aagaggcatt
   122941 ttttcaaaga aagatattga attgactatt ggatgggaaa agaaagataa tttagaacaa
   123001 aaagatttaa aacgagagat agaacaacta aagtcaatta taaataatat ggggtttgat
   123061 aataaaaatg ataatgatat agataaaata tgcaagaatt tactaaactt agatttaaat
   123121 caagaaattg tagaatttat aaaagctgat ttacaagaaa tgaagttcaa tggaattgat
   123181 acaagtaaaa atttagtaga aagtctaaag aaaaagatta aaatagaaaa tcaagcaata
   123241 aatggtaaaa ttgctttagt tggaccacca ggagtaggta aaacgactac aatagcaaag
   123301 ttggctgcca aattagtttt tgaggaaaat aaaaaagtag gagtaataac tatagataca
   123361 tacaggattg gtgctgtaga acagttaaag atatatactg atataatgaa tattcctttt
   123421 aaaggggtaa taagccctga tgagatggaa ttggcacttg atgcgatgaa agattgtgat
   123481 gttgtattaa tagatacaac aggtagaggc tataaaaact ctatgcaaat attagaaatc
   123541 aaaaatctta tagataaagc tgaaactgat aatatacatt tagttttgaa ctgtacaaca
   123601 agagaaagtg atacaaaagc aattatagat tcatatagaa atgtgaattt taaaagctta
   123661 ataattacaa agttagatga aacaataaca tatggctcaa tatttaacat aatgaattat
   123721 gcacaaaaac caatatcata tattacaaca ggacaaaatg ttcctgatga tattataaaa
   123781 cctaatgaag ataagattat aagattacta ttaggagttg aaagtatatg atagaccaag
   123841 ctcaaatttt gagaaaaatg gcaatggaaa aaagaggttc tgatgagatt atagtagaga
   123901 atgagaatat gcctaagata attacaatag cttctggtaa aggcggcgtt ggaaagagta
   123961 atctcgctac aaatttgtct atatgcttaa ccaaacttga taaaaaagtt cttatattag
   124021 atgcagatat aggaatgtct aatatagata taataatggg ggtaaatgta aaagggacta
   124081 taattgatgt aattaatggc gaaaaaaata tagaagatat aatttcacag actaagtatg
   124141 gtgtaaatgt aatatctgga ggttctgccc ttaatcatat agaagacttt acagaagctc
   124201 aaagaaataa gtttatacat agcatagaac agattcacaa tgtggatttt ataataattg
   124261 atacaggagc tggtatgagc aaaagcctat tgtcatttat atactgtagt actgaatttt
   124321 tcttaataac aactccagaa ccgacatcat tgactgacgc atatagttta ttaaaagcta
   124381 taagtaattt tggcataaag aaaagtgcaa atataataat caatagggta attgatttag
   124441 aagaagcgaa atctacatac aaaagaataa aaatggttgt ggacaaattt ctaaacctta
   124501 atctggaatt gtatggatat ataatagatg acaaaaaagt aagtttatgt gtaaaaaaac
   124561 agataccatt cattttagaa tatcctacaa gtattgcatc aaaatgtatt atagccatag
   124621 caaagagaat ggtaagtcag tcaagagaag atattgttga taataaaagt tttctaagaa
   124681 agatgtttag tatatttaaa agctaaggag gcgtagttaa tgaatagaga agaattaata
   124741 aaagagaata tgcctcttgt aaagagtata gcaagaaaat tttttatacc agggaaaggt
   124801 tttgaatatc aagacttagt aaatagtgga gtcattggat tgattgatgc aataaataaa
   124861 tttgatgctg aaaaaggggc aaagttttct agttactctt atataaaaat aaaatctgct
   124921 atattagatg aaattagaaa tcaaagtcca atttctaaac ataatctaac taaagtaaat
   124981 aagtataata gagtggtaga aaagttgcaa tctaaattat taagagagcc aacttcatat
   125041 gaaattgcaa aagaattaaa ggtttcagaa aaagaacttc atgatatcga aagtaatata
   125101 gatatgttaa atattgtatc attaaactat gtaatctttg aagatacaaa tgaaactgta
   125161 caagatgtaa taagtgatag agaagaggaa gctccagaaa atataataga agaagaagaa
   125221 aagttagaga ttctatccaa agcaattagt aatttaaatg aaagagaaaa attaatactt
   125281 tcactgtact attatgaaga tttaaatcta aaggagatag ggaaagtgct aggtgtttca
   125341 gaatcaagag tttcacaact ccacagaaaa tcaataagaa acttaagaaa caagataaaa
   125401 gaacttaaat attctatata gatggtgatt gataagatga tacaaattat attaatagta
   125461 gtgtctattt taataatagt aactatagtt ataaatttac ataaggaatc aaaaaataaa
   125521 gataacagat actttgataa aatatttgag caagaatatg aagcaaatga tagattaata
   125581 attgcagaaa aaagaagatt ctttttagac aaagtacttg ctgaaataag aagtaataat
   125641 catataaaag tttatgaaaa ttataaccta ataaaggcta atgaagaaag aaaggaaaac
   125701 atatttatag aatcaaaaaa ggaagtaaga caagaaaatg agttatctct taaagtgaaa
   125761 catcttataa gttcaggtta tgatgatgtg gaaatatgta agatgctaga tattggaaag
   125821 ggggaactgt cattaataag gagttgttac aaaatataag gatattatta tgtgataaaa
   125881 aagtattctt aggaataggt attggtatat taatatcaac tttatgtata atgcttttta
   125941 gtaataatga tatgagtaag gcagagatag aaaaaaaggc cagagcgtta ggcatgaaat
   126001 atacaagtga gatgaaagtc ttagaataga tgatactgtt tagacattta caaaaaagga
   126061 ggtcataatg tgataagagg attatataca gcagtttctg ctatgataac taatcaacaa
   126121 aagcaaaatg ttgttgtcaa taacctagct aatatggata caaatggata taaaagtaaa
   126181 caacttttga ctaaaagttt tgatgaatta aagttggaag gttacaataa ctacgcaaat
   126241 ggaactaaac aaaagcagat tataggcgat ataagtccag gtatttctat ggatgaaact
   126301 atcacaaatt ttaatcaagg acctataaaa actactgata ataaaatgga tgtagctatt
   126361 caaggtaagg gattttttct agttagtgat gcagctggaa atcaatttta cactagaaat
   126421 gggaacttca gaacagacaa tcaaggtgac cttataacaa gtgaagggta ttatgtactt
   126481 gggacgaata ctgctactgg tgctgtaggt catataaatg taggaaatca aaaatttgaa
   126541 gtggcaaaag ataatacaat atcactagac ggaaatgcta tgtataaatt taatattgta
   126601 gattttaata actacaataa cttaaaaaaa gaaggagata acttatattc tggaggagga
   126661 gctatgaaag taaataatgc acttacaata caaagtgcga tagagtcctc taatgtagat
   126721 atggtatctg aaattaataa tatgatgaca atatcaagag aatatgaggc aaatcaaaag
   126781 ataattcagg ctatggattc taaattagca aaaatagcaa gtgagattgg ttcagtaaga
   126841 taggtaatag gaggtgaatt tttatgtaca caatgtttta tactagtaaa acagctttat
   126901 cagcaaatca aagtaaacta gatataatat ctaacaatat agcaaattct gattcaacag
   126961 gatataaaaa aataaatatg gaatattctg atttagtgga tgaagtacta aatagaccat
   127021 cataccctac aaatggtaaa gatatatcga ctggaacagg agctaaggca acagctccca
   127081 tgagaaatta tgaacaaggt gcattggctc ctacagatag taagagtaat ttggcgatag
   127141 atggagaagg attctttaga gtgataagaa aagatggtac atatgcatat acaagaaatg
   127201 gtggatttaa tgtagatgct ttaggtaaga ttgtagatga taatggaaat atattagatg
   127261 tccaatttga tgcaggatat aactataata atacaaatat agatagtaca aacctgacag
   127321 tttcaagaaa tggagagcta ttcgtagata ataaaaaaat aggaaaaatc aacttatatc
   127381 aacctatagg aactcaaaat tttatatctg aaggagatag tttattcgtc gcaactgatg
   127441 cagcacagat taaacaagtt gagaaagtcg atatagttca aggctataga gagaggtcaa
   127501 atgtttcttt acaagaagaa tttgttgact taatagccac tcaaagagca tttcaaatga
   127561 actcaaaggg aataaagaca gcagatgaaa tgtggcaaat agcgaataat ttaagagcta
   127621 aataattatg taaggtgagg aatattcatg aatgatatga aagagtacga ttttggcaaa
   127681 cctcagagtt attcaagaga aaatttaact tgtttaaatt ttttattagc tgaattttgt
   127741 aaaaaatata aaaactatat aatttatgaa cttaagtgta attctagtat ggttgttgat
   127801 agtatagacc aagtaaatta tcagactttt ttagatagag taacttcttc gtgcgtagta
   127861 gtacaaaatg caatggaacc tgttatgaaa aacttttctt ttagaataga tagaagtgta
   127921 gctgatatgt ggattgatat aacttctgga ggaactggag ttgtaaagga taatgataga
   127981 gagcttacag aacttgataa aaaagtgctt ttacacctta tggatgattt agtaagaaat
   128041 atgcacttat ttgagggttt tgaaaatata caagtattgg atacacatac acatattaat
   128101 ttaccacaat tatgttctcc aactgcacca gtatgcgttg tagatttaaa agtgctaaat
   128161 gataatgagt atattggaag tgtttctctt tgttttccat acaatggttt agaagctctg
   128221 ttagaaagta tatctgttat agaatttttt gataatgata taggagatga ttcagaggaa
   128281 tttaccaaaa aaatatataa tagtgtatct aatatagaat tatcggttat tgcagagata
   128341 ggaaaagtat caattaatgt tgaagactta cttaaactag aagttggaga tgtaatagta
   128401 acaaataaaa aaataaatga ttatatagat atatttgtag aaaattcaaa atcatataca
   128461 gcaacaccag gatttatatc aagtaaaaaa ggtgtaaaaa taaatgatgc tgttggaaaa
   128521 gaggtgtagt tatggacaat agtaatctta tttcagatga agaagcaaag atgctattaa
   128581 atgataaagt tgaaagtgaa gttgatggag atgatgagtt agccttagat gtgtctgaag
   128641 ttaatcgaaa taatatacaa aggatacttg accttaagtt agaattatct gtggttatag
   128701 gaagaactaa gatgactcta agagatattt taaacctaca taaaggttct cttattgaac
   128761 tggatacttt agcagaccaa gatgtggaaa tactaataga taataaagtg ttggcttatg
   128821 gaaaagtagt ggtggtagat ttaaattttg gtgtaaagat aacaagtata gtaagtgaag
   128881 aagatatggt aaaatctctt gtttagagat aacatcaatt aatacttaag gcatgaggtg
   128941 gtacttattt taaacttaaa tgatataaaa aaagatatat taaaactcaa taaaaaagac
   129001 tcatgttctc tatataatga atctattaat aatataaata ataattgtat atcgagtgga
   129061 ttgaaatttt taaaacaagc aagagattta aacccagatg atgttgatat attaaatctc
   129121 acaggtcttg taaatttact aaaatgtaat tttgatgagg ctgtagaaag tttctataag
   129181 agttcacttt gtgaaaaaac tgctctgtgt gaaaagtata taaacatgct tacatctgag
   129241 gagtttttaa ttttctttga aaggtacaat caactcataa ggttaataaa cagaggaatg
   129301 tataaagaag ctatacaagg gtttaaactt ataactgagc aatactgtga tttaatagaa
   129361 ccttatgaat tgcttgcctt actgtatgac aaggaagaag aatatataaa atttgatgaa
   129421 tgtttagaag tattgaagat tattgataag gaaaattatt tattaaatca agaaaataac
   129481 acattagata tgtataatag tgctaatata caaactaaaa gtaatataaa agtagatgat
   129541 tataagaatg agttcttaca taaaagtagt agtaaccata aaattaatga ttataatgat
   129601 gtaactaaag aaaagagttc aagcaaaaac cagaaaagtt cagattctaa taagaaaaaa
   129661 agtattaaaa aaaataaata cctatatata gccataatat taggaatatt attagtagga
   129721 caaagtatat atagttctta taagatgaat aatttaactg ataaaatatc taaaaataat
   129781 gaaaccaaaa atgaagagtc aatagattct aacttgacta agaaagaaaa taatatagaa
   129841 gaaaatgaag atatgagtaa ggcttctaat ataaataaga gtaataaaaa cattaataaa
   129901 gaggatgatg taaaatctaa aaaaaatact gtagaaaatg aagatgataa agattctgac
   129961 ttatttacag aggatgaatt gatgtctaag gcgaatactt taaaatcaga aaagaaaact
   130021 aaatcttcta tacaactata taagaaagtt gcagatatag gtgaaaataa agggaataca
   130081 tctgaagcaa cttatcaagt tgctattcta agtgaaaagt taaaagacta taaaactgct
   130141 gaagaatatt ataaaatgta tgtagaaaat tactcagaaa aagatgctta ttttgatgaa
   130201 tcttattata atttaggtat gatgtactat aacaatggtg atttaaaaaa ttctaaattg
   130261 acattaaaga agttggttaa taaggtacca aatagtatgt ataataattc aaaagtaaaa
   130321 gaaattttaa aagaagaata gttaaattag ataagaaaaa taaattattt tattttaaaa
   130381 taatatgatt ataatatatt gacataccat tttaaaaaat ttaaaatatt aattataaaa
   130441 tgaggaggga taaaaaatgg aatttgaaaa agggagtatt tcaattcata cagaaaatat
   130501 ttttcctata attaaaaaat ggttatactc tgataaagat atatttataa gagagcttat
   130561 aagtaatgga tgtgatgcag taagtaaaca taaaagactt gtatcactag gagaaatatc
   130621 agaaaataag tcatcagatt ataaaattac agtatctgta aataaaggag aaggtacact
   130681 taaatttatt gacaatggaa ttggtatgac tgaagaagag ataaaaaaat acataaatca
   130741 agttgctttt tcaggtgctg aagatttctt taataaatat aaggataaga tggaagagtc
   130801 aaatgacata ataggtcatt ttggattagg attttattct gcatttatgg tgtctaaaaa
   130861 ggtacaaata gatacccttt catatacaga aggtgcaact cctgtaagat ggatatctga
   130921 aggtggtaca gaatacgaaa tatctgaatc agatactaga aatgatagag gaactactat
   130981 aacactattt attgatgatg atagtaaaga atttttagat gaatttactg taagaggaat
   131041 aataaataaa tactgttctt tcttaccagt agaaatatat ttagaagatg ttgaaagatt
   131101 agaaagagaa gctaaagaag cagaagaaaa agctaaaaaa caaaaggaag atggaaaaga
   131161 agagattgta gatgcaaaag taattgagcc tttaaacgac actaatcctc tatggttaaa
   131221 atctccaaaa gactgtactg atgaggagta taaagagttt tatagaaagg tattcaatgt
   131281 atttgatgaa cctttatttt ggatacattt aaatgtagat tatcctttca atttaaaggg
   131341 tatactttac ttccctaaat taaaaaatga gtttgaactg actgaaggaa aagtaaaatt
   131401 atacaacaat caagtgtttg tagctgacaa tataaaagaa gttataccag aatttttact
   131461 tttattaaaa ggtgttatag actgcccaga cttaccatta aatgtatcaa gaagtttctt
   131521 acaaaatgac agagacgtaa gcaaaatttc taagcatata attaaaaaag tagctgataa
   131581 gttaaaatct ctttgtaaaa atgaaagaga agaatacaat aagttttggg atgatataca
   131641 aatatttatt aaatatggtt gcttaaaaga tgaaagtttc tatgagaagg taaaagaatg
   131701 tatattattc aaaactattg atgatgagta tataacatta caagattatt tagaaaaatg
   131761 taaggacaaa catgaaaata aggtatttta tgtaagtgat aaggaacagc aatctcaata
   131821 cattaaacta tttaaagaat acgacttaag tgctgttgtt ttaaactcat caatagatac
   131881 tcattttatt tcatttatgg aatataaaga gaatggagtt aagtttaata gaatagatgc
   131941 agacctttct gatgtattaa aagataaaaa tgaaaataaa gatagtgaag aaaacaaaga
   132001 agagatagct aagatagaag gtctgtttaa agaagctgtt ggagaaagag tgaagcatta
   132061 ttctgtagaa ggattgaaaa atgaagacac tccagctatg gtgttagtat cagaacaatc
   132121 tattagaatg gcagaaatgc agtcaagatt tgctggaatg gatttaggaa tgaattttga
   132181 ggaagaaaaa actcttgtaa taaatgagaa cagtccaata atcaaaaaat tggtttctct
   132241 taaagatgat gaggaaaaga aagataagat tacgcttatt tgtaaccaga tagcagattt
   132301 agctttactt tctaataaag aattaaagcc agatgagtta gattcatttg tacaaagaag
   132361 taataagctt atgagtcttt tcatagaatt ataagattga atttgaatac attgaagcaa
   132421 atttataaaa agtattcaat atcagtgatg ataaagaagt gtctcaaaat gaacttttca
   132481 gttcatgggg cgcttttttt atgtgaaatt aaatttattt taatcatttc aacaatgaaa
   132541 aatatattta tctctatttt gagacagacc attctttatt tttttatctt tggttaattt
   132601 ttaaatattt aagtaggttc taataaaaaa ctctatttag ttaaatatag ttaacttgat
   132661 atataataag ataatacata taattaagta aaagattgtt ttttagttta tgtttaaata
   132721 cataattaca ctttgttaaa aacataaaat tattactaaa gtagaaatag gaggttttag
   132781 catgaatttt aattataatt tgccagtaaa tatcttattt gggagaggca gaattaatga
   132841 tgtgggaaaa gaagtatcta aatatggcaa aaaagtattg atagtaacag gtaaaaatag
   132901 tacaaagaaa actggattac ttgataaaac aatagattta ctaaaagact ctaaaataga
   132961 atatgaagtt tttgatagag tagaacaaaa tcctcttata actactatat attcaggagt
   133021 agaaattata aaatcaactg gatgtgattg tgttttaggg cttggtggtg gaagtattat
   133081 ggatgctgcc aagagtatag ctttttctta taaaaattca ggagatttaa atgattatat
   133141 atttggaatt agacaaggtg aagaagcttt acctataatc ttagttccaa caacatcagg
   133201 tacaggtagt gaaggaaatt gttttgcagt acttacaaat tcagaaacta aagataaaaa
   133261 atctataaag aagaatagta tgtatgcaaa agcatcaata attgacccag aacttatggt
   133321 tacaatgcca aaacatataa ttgcatcagt tggatttgat gcacttgccc ataatatgga
   133381 agcatatctt tctaatggaa gaaaccctct tgcagatgta caagctattt atgggattga
   133441 acttatatca gaaaacctaa taaaggtata taatgatgtt aatgatttag aagcatggga
   133501 aaagataaca cttgcaagta ctattggagg aatgacgatt ggtacagcgg gtacagcctt
   133561 gccacatgga atggagcatc ctgtaagtgg tcttagagat gtaatgcatg gaaaaggact
   133621 tgcagctttg actcctacta ttatagaaag ttcatgggat agtgatattg aaagatttgg
   133681 taatatttca aaggtattag gaggaacttg tgcagaagat tgttcagatg caattagaaa
   133741 tttccttaaa aaaatagatt tagatataaa gctaagtgat ttaggtattg aaaaatcaga
   133801 tatagattgg ttaactgata attgtatgaa aatatcagtt gcaaatatta agagacatcc
   133861 aaagtatttt aataaggaac aaataaagga aatgtaccat aagtccttat aatttgactt
   133921 tacatattta gttttatata aaaattataa attaataata aaaaattaaa gattaaattt
   133981 tatatctgat ttttgattat ccgcataaac actatacttt caaacatttt gaagtataga
   134041 aaactattca ttttaccacg aatttaccac gattgaatga gccttgatat gacacaaaaa
   134101 caacatggga gatagcacaa atatctgtgt atctcccgtt tttcattcat gtagtatgat
   134161 tattttactc tgatttcaaa tttcaagatt gctttcatca tttctgtatg gatttgacct
   134221 tttaattctt catcaacctg cataatgatt ttaccacttt cagagtggta aaacggacgc
   134281 aagcataatt tacatatata agcgtcataa aacttcaaaa tctctcttat ggcagtttca
   134341 tttccagcag acgcttgaca tattactttt aatgtagggt agccatattc ttttttcatt
   134401 ggttcaattc ctttctttca atactgtttt tagtttcttc aatccgttac ttcttctgcg
   134461 ataaatagca gaacgtgata catgatataa ttcggctatt tcttggtcgc tcatactttg
   134521 aaaatagcgt aatagaatta catcacgctc tttattcgat aacttatata aagcaacagc
   134581 aagtttctca tttgatattt gaattgtaaa attcaagact tcaaacgaaa tgtaatcaca
   134641 agaatagtta tccttagtta cacattcaac atttttcgta tctgataatt cacagaataa
   134701 aacttcacgc ttagaacgtc ttgcaaactg tctgtttctg ttttttactg tgcatttaat
   134761 aacagtcatc atcaaagcat taaactgtat tctaacgata tgctcgaaag aagatgggtt
   134821 cataatctca cctcctttcc gcatacgctg aaatatataa acggagatac cgtctatatc
   134881 tttggaaaat acaaaaagaa gaacaagaaa aaagtccgta caaaatatac cgtctgtacg
   134941 aacttttaat attgtaaaat atttagttgt tgataaaatg ctgttaggta gtgcataatc
   135001 gtataagatt attcctaaaa ctttccacag cagttacttt caatgctttt atatcttgct
   135061 tttttagtcc tatcataaag ttttccatat aaccgcttaa taatttgatt acttgttaaa
   135121 atagttataa tgcaggcgac tatgtgactg attaaaatcg ctatccaaac accatttaaa
   135181 ttttctgcca gccaagataa tagataggca aaaggaatac gaataataat atagtagaat
   135241 atcattagta tcatactttt tgttggtttt cctataccat ttaaagtacc taagtagcaa
   135301 ctagtaatag tgtaaagaac ataaccgata ctaacaatta aaaaataatg gctgacaaca
   135361 tttgttacag ctacgttgga aacaaacaat tttgccaact gtttagagaa gaaaataaca
   135421 actgctgata atacacttga aacaacaata ccatatttta acgccaattt cagataattc
   135481 tttgctctgt cgatacgttg tgctccaata cattgcccta cgattgaagt caacaccata
   135541 ttaagagcca tagcaggata aaataatatc atttctaatt ttccagcaac tccgtagcca
   135601 gcaatagcag aaatactata agtactaaca atagcagtta aaaatgttgt actaatagca
   135661 ggaatacttt gttgaatgac agacggcaca gcatttttta caaacggcat aatctctttt
   135721 gtatcaaaat cagatagtga aaggttaaat aattttttat gataaatata aatgcacata
   135781 aacgccaaac aaataatctg tgatattaag gttgcgattg ccgctccgtg aaatccaatt
   135841 atgttaatga aaataggatc taaaatagca ttcaataaag tagacacaag cattgcaact
   135901 gcttgaaaca tagtattgcc aaaacttctt aaaatggctg taaagtataa atacaaataa
   135961 actgctacat atcccaaagc atatatagat aagtaatttt ttgccatatc aaaaatttca
   136021 gtcggtgtat ttaaaactat caaaataggc tctaaaaaaa tctccaacac aattgtcata
   136081 aacactgaaa gaattataga tacaaaaaaa gaagtaacta taatattctt tttcttttgc
   136141 tcatttttcg caccaattac ctgtgataat agaatggcta acccgtttgt tgctcccata
   136201 ccaattgaag ttaagattaa aataataggt gtcgagtttg ttaacgctgc gtatgcctgc
   136261 tcacctaaca aatttccaat ccaaagactg tctacgagat tatatgccat atttaaaaac
   136321 atagctatta tcataggaac agtcatttca agtaaacatt tttttgtgtt tccgtttaca
   136381 aaatcaatat ttttgttcat tttaattcct cctattgaat gaaaattatt catttaattt
   136441 atttaaatat tccctgcctt ttggcagggg aagatttaaa gcctaaacaa gtccctaaaa
   136501 aatgccttta tccgtgaact cttttcttta attgatatat cggtatttaa aataattcct
   136561 agttgtccat atatgcaaaa actggcatac atttcaacat cattgacttg tatttcattt
   136621 gtgtaatttg ctctttcaat aatttcagat acaataggaa aaagtttttc acatacattc
   136681 aatgttaata aattatggaa atttttattt tggttattat gaaaaactgg ataatatgta
   136741 tcatcttctt gttctgcaaa aagtatcatc ttccgcaaaa tatcttttaa actatccttt
   136801 tttatattta tattttttgt catattggcg actaaaatat ttgaatattc attgatagca
   136861 gactgaaaaa gtacatcttt tgatgggaaa tatctataac ataatccttg tgctattcca
   136921 atttcttttg ctatgtctga tattgaagtt ttttcaaacc catttacact aaataattta
   136981 atggctgttt ctaaaatttc ttgtttacgt tcctctggtt cttttgaaat acgcattgtt
   137041 ttctttcctt tcttgcggtt taattattgt atgctataat taaacaagat cttgtgccaa
   137101 aagatttcca ttcaatttcg tggaagtctt ttgataataa taacaacatt tccttttttg
   137161 aataaatctt tacatctcca ctattgctgt gtttcatata gtaattcatt atctgtcttg
   137221 ctccgattgg ttgccaacaa tcaccgataa tgaatactcc attttgcttt aaacacctag
   137281 acacttcttt ctctacaata tctggttgtg gataatgatg aaatgagtca ttacatacaa
   137341 tggcgtcaaa agaactatct tcaaaaggta atctctcaga gtcgcctaag ataagtgttg
   137401 catcatttcc tagtttattt tttgcaattt caagcatatt gggagatata tctattccaa
   137461 atagttgttc tgctatattt aattctttta tttctttaag taacgcaccc gttccacaac
   137521 ctaaatctaa tatagaatgt atattcttat tttttaaatt ttctataatc ggcttataga
   137581 gttttcgagc atgttccccc tgaatatttg tatcataatc ggcagcttgc ttatcaaaag
   137641 tcttttgtga tttttgtttc gtaatattca tgtaatcaac tcctttcact aaaattatat
   137701 ctcgtgaatg aacgattgtc aatgaatgaa attcattgaa tttcattcat ttcaaagacg
   137761 tgtatctctg atttaaaata cacgcctttt tgattaccct acaatcttcc agttactatt
   137821 ccttatatag cccaaacttg taccgtgaca atttcattga tattatccga tttaccacaa
   137881 atcaaatttt atcttttctt cctcttgatt accctccaca gaaaagaaaa agccctgtca
   137941 agagccttgc caccattggt ggtgctttgc actctttact gggctttttg tttgctgtat
   138001 cttctacaaa gaggaaaaaa gttattcgtc ctcatcatca aaatggttat ttttcaatac
   138061 ttcccgtaat aattccatat cttcttttgc atttgggttt atcattttta cgacttgata
   138121 aggtgtccta tatttatgtc cctctatgct ttccccgaac atatccatgc tgtataaatc
   138181 atcatagcgt tctaacagtt tttgaaattt caaatgctgg ataaattctt tgattggata
   138241 aaggtcggac gctacaatac ttttcccgtt gatgtagtcg gtaatatatt cccgtaactt
   138301 ttccaactca tattccagcc attcttcctc gctgtcaaag aagttgtcat aatgtccatg
   138361 ttttagttct gcatttaatc gttcttcaat tcttaaaaac tggcagactt ccttttcggc
   138421 ttgattaaca tacttccatt ctcccgataa taattcattg ggcgttactc ccagcacgtc
   138481 cattatcttc tctaacgtat caaaggtagg ataattcacg ccacgttcaa tcttggaaag
   138541 gctctgcata ttgataccga ttttatccgc aagttcttgt tgtttcattc ctctgtgttt
   138601 tcttatggtt tgtatgttct ctcctaagaa actaactttc ttttcataat gctccataac
   138661 ttagtataac cgctcctttc gttgcttttc ttggtattta taagcatatc atacttaata
   138721 tatatctaaa agtcaacaaa aacttcttga caagtaattc taatggcgtt attatcatat
   138781 cagttagagt gattaagcac actagggtca atcacacgct tgagtaagca tagaaaagat
   138841 atattttcac tttgatagca tgaataagca tggactatca gaccgaaaat aaggtttctg
   138901 actggggctg ttccgtttag ccacgagcct tacaaggctc gtgagcgtta agaacggatc
   138961 agacacagga agaaagggaa cgcctttagg cgttcgtaaa gggcgtatat gtaacaccgc
   139021 cctgcgtata catgtcatag tacctagaaa ctgtgataaa taaaggaaaa aacacgattt
   139081 ttaccccgca aaaaaacggg gcatacgaaa ggagcaatgc actataacta cacacaaaaa
   139141 tttatccgtt aagattgatt acatcagcat tgtatttgaa actgcaaccg ctgaagatgt
   139201 aatcatgcac attttagatt taccgactga cattttcaat gtttatccag caacgataaa
   139261 attcaagact tatcaagcac gctggcagat tggagatatt tatgtatcgg gggacgcaag
   139321 aaagacagag gacaacccac agggactagg ctgttatctt gttatgactg gcagaggttg
   139381 tgatgatatt ttccgtattc tcgacagtag gaattatacc tttggggata tgttccgacg
   139441 ctgtgagcga agatacggac tggataattt ccatttcaca agacttgata ttgccattga
   139501 tgataagaac gaaaagccat tctttaccat agagcagata aagaagaaat gcgaaaaaga
   139561 ggaatttatc tcgaatagtg agggctacca ctttgacgaa agcaagtttg atgatttcga
   139621 caccgcaaag actgtttata tcggtgctgg taaatcggga ttgtcctacc gcttttatga
   139681 taaagataag gaagtctgtt caaaacataa taagacactt gatgaagtcg gcagttggaa
   139741 acggacagaa atgcaactgc gtgatgataa ggctcatgct tttgccatga cattcaaaga
   139801 cagaccgctg gaacttgggg aactggcttt cgggctattg gcaaacaact tacgctttgt
   139861 cgtgccaaac agaaatgaaa gtaataagag cagatggaaa acgtgtcggt tttgggaacg
   139921 ctttttaggg gctgtggaag tcttgaaact gcaagtaccg aaactacata attctcttga
   139981 agaaacacag caatggctca cagagggtgg tgtgatttcc gctgtcaaaa gtttttactt
   140041 cttagaagaa catgacgcat taggtggact ggaaaaagtg ggaactatgc ttgataaggc
   140101 aagatacagc aattcccttt ccagtaaact aaccgcccac ttacagagga tagaccgcac
   140161 cgaccttatc ccctatatcc agtatgacac gaaacatggg aaagggggta tctgatgaat
   140221 aacaacgata ttcctgtatg ggaaaaatac acccttacca ttgaagaagc gtcaaagtat
   140281 ttccgtatcg gagaaaacaa gttaagacga ttggcagagg aaaacaagga cgctggctgg
   140341 ctcattatga atggcaaccg catacagatt aaacgccgac agtttgaaca ggttattgac
   140401 aaattggacg ctatctaatg caaatgagcc ttgtatgtgt tatgatgaac acaagtcata
   140461 tcaaggctct ttccaacaag gaaaggagca gacaccatga aagaaaaaag acgggatagt
   140521 aaaggacgta tcctgcatac tggagagagc caacgaacag acggaaaata cttatataaa
   140581 tatgtggacg catttggaaa cacaaaatat gtgtatgctt ggagattgac acccacagac
   140641 ccgacaccaa agggaaaacg ggaaaaaccc tcacttcgtg aactggaaca gcagataaga
   140701 cgggatattg aggacggtat cgacagcaca ggcaagaaaa tgacgctttg ccaactctac
   140761 gccaaacaga acgcacagag ggcaaatgtg aagaaaagca cacagaaaca acgggaacag
   140821 ctcatgcggt tattgaaaga ggacaagtta ggtgctagga gcattgatac gataaaaccc
   140881 tctgacgcta aggaatgggc gttacgcatg aaagacaaag gcttttccta taacaccatt
   140941 aacaaccata aacgctcgtt aaaagcgtca ttctatatcg ccatacaaga cgattgtgta
   141001 aggaaaaacc cttttgattt caagttaagt gaagtcatag aaaatgatac caaagagaaa
   141061 gtcgcattga cagaggaaca ggaacaagcc ctactctcat tcatcaagac ggacaatgtg
   141121 tatcacaagt attatgatga tgtgctgata ctgttaaaga caggacttcg tatctcggaa
   141181 ctgtgcggac taacaatcat ggacattgat tttatccatg aagttgtggt tatcaaccat
   141241 cagttattaa agagcaagga acagggctat tatattgaaa cgcctaagac aaaaagcgga
   141301 acaaggcaag tgccattaag tagagaaacg atacaggcat ttcaacgggt tataaagaaa
   141361 cgcccaaagg cagaaccatt tgtgatagac ggacgaggca actttctatt tgtcaatcat
   141421 aaaggcaagc ccaaagttgc gattgattac aatatgcttt ttgtccgtat agtaaagaaa
   141481 tacaacaagc accataagga taaccctttg ccacatatca caccacatac gctacgccat
   141541 acattctgca caagattggc aagcaagaac atgaacccga aagatttaca gtatatcatg
   141601 ggacattcaa acatcagtat cacaatgaac tggtatgctc atgcgtccat agataccgca
   141661 aaatcagagg ttcagcgtct aattgcataa gaagtattta ccacgatttt aaccacgctt
   141721 gatagcgaaa atataagaag atagacctag atatgtgagg tttaccacaa aagcaaaatg
   141781 cccgtagagc cgataaaata aggctttgcg gacatttaag aagatataaa aagatagtca
   141841 aaaagacata tataatttat aagtaattaa tagtaaaaaa attgtgtata gaagttatat
   141901 atataataaa tttgtcttaa gcttttattt tactttctaa taaataaagg agtttaaaaa
   141961 agggaagatt aattaagtaa tattttataa aattcttcga tttaaaaact ttaagtagag
   142021 gtgaaataaa tgtttaatcc caaaagaata atattcgaaa aaggaacttt agacactgat
   142081 gtgggtaaaa aaatatacaa taaatttaga gataataaag atgtagagat aattaatata
   142141 tcatcaaata ggattaaaga acatattcca ggtgaaaatc tatatgaaca atatagaagt
   142201 gggaagcaga ctatggtagt tgggattaga aaaagtctga agtttcaaac atgtaaacct
   142261 tctgctaatt atcaactacc acttgtcagt ggatgtatgg gaagatgtga gtattgttat
   142321 ttgaacacac aattaggtga taaaccattt ataagggtat ttgtaaatgt agatgaaata
   142381 cttgaacaga caaaaaaata tattgaagat agaaagccac aggtaaccat atttgaaggg
   142441 gcagctacat cagacccagt tccagtagag ccatatacta attctttgaa gaaaacaata
   142501 gagttttttg gaagagagga aaaaggaaga tttagatttg ttactaaata cagtgatgtg
   142561 gatagcttat tggatgctga acataataat catacagaaa tacgatttag tatcaatact
   142621 cctagaatta taaatgaaca tgagcattat acagcctctg caaataaaag aatagagtca
   142681 gctgtaaaac ttgctagggc tggttatcag attggtttca taatagcacc tgtgttttta
   142741 tatgaaggtt ggaaagaaga gtataaaaat ctgattataa gtataaaaga agctttacca
   142801 aaggattttg ataaaaaaat tatatttgaa gttatatctc atagatatac aactaaagca
   142861 aaaaatagaa tactagagat ttatccagat acactattgc caatggaaaa tgaagataga
   142921 aagtttaaat acggtcaatt tggatatggt aagtacgtgt atgataaaga acaattagat
   142981 gatatgaaag agttctttct taaggaaata aatggagtat ttaaaaatag tttaataaaa
   143041 tatataatat agcaaatctt acctaaagat ttgctatatt ttatttttat atattttatg
   143101 tttataataa agcaatgaga tttagcacta tcatataaga aaattaaaaa gggcactatc
   143161 tatcaagaac attttttcta gttttgatac tataaaggat aagagtaaca aaaatatcag
   143221 gaggagttat agtatgcatg catgggagtc tattcaaatt acattggatt taatagaagc
   143281 aaatttatca gaagaaatat caattaatga attagcaaat aaagcaaatt tatcaccatt
   143341 ttactatcaa agactattta aaagattggt aaataagact gtaatggagt atataaagct
   143401 tcgtcgtctt gcaagagctt ctgaatactt agcagaacat aagaatcgta tacttgatgt
   143461 agctttaaat tttggatttg ctagtcatga gacatttaca cgttccttta aaaaagcata
   143521 tggattaact ccagaaaaat atagagcaaa tccagtaaaa ctcaatcact ttattaagcc
   143581 agaattaatt ttaaattatg ctatggttga tgaaggtgtt ccactgattg cagatgatat
   143641 agtgattgaa gtcaatcgta agacattgag taatccaagg acatttgttg gaatagaaat
   143701 agaagtacct atttgccagt tggtgggcgg tgaaacaact ggaattgcaa tagtagagga
   143761 attatggatg aaacttggaa gtcaaagaca taatatacca aatcaaattc caggtggaaa
   143821 tgaatttgct gctctttata tgggaaatgc aaaagaagga aattgtatgt atatggcagg
   143881 tgtagaggta gagtcaggta catcagtaga aggatatagt acttttgagt tgccagctaa
   143941 agaatattta gtatgtggat ttgaggcaga aaactttaat gagttagtta attcagctgt
   144001 ttttaaagca gataaattta tggaaagatg gatgaagaaa cataatttaa caactactga
   144061 ttttgcaatt gagatgtatt accccactac acctgaagca gcatatctgg aacattggat
   144121 tgttccggtt cctattgaac aatagaaagg atgatgaata tgaattggca agatgcgttt
   144181 tttcaagata ctaaacctac atttgagcaa attaatgaat ttattaataa tccattatgg
   144241 gacaagttaa ataaaacttt ggtttctact tataatgtag aacctaagct tgaatacagt
   144301 aaatgttcaa tgcaaagagg ttggaatgta aaatataaaa aaagaggtaa atcactatgt
   144361 actttatatc cacaagaagg ttattttaaa gctttggtta ttgtaagtga aagcaataga
   144421 gtagaggttg atttatttat taatacttgt tgtgattata tcaaaaaaat atataatgag
   144481 gtaaactttt ttaatggaag taaatggcta atgattcaag tagatagttt attggtatta
   144541 aacgatatgc ttgaactaat taaatttaga gcttaacata tagaacagga tgaatatata
   144601 agtcatcctg tttttatatt caatcagata aattaatata tagtctataa tatgaataat
   144661 ttagtaaatt taaatttact ttatctttct acattctttg caactaagtc cacatgtgtt
   144721 tttttcttgc atattagtag caccccaatt agcaaattgt tgtaaaatag gcacaatact
   144781 tttaccttta cttgttaatg tatattcaac ttttggagga atttcattat attgtttacg
   144841 atgaacaata ccagtagact ctaaatcttt taatgattga gctagcatag tatttgtaat
   144901 gccatccaat tttcttttta tgctactata tctaattgga ttttcaactg ctaacataca
   144961 tataataggt aatttccact taccaccgac aatgtctaat gcataacgga ttggacaggt
   145021 taattcttca acgtttttag ttatattttt ttcagtattt atactcattt taattactcc
   145081 ttagttatag tagtatcttt tttatacttt atcagaaaaa actgcatact tgttttttct
   145141 gtattttata ttaaaattat atcaaaggat aatccttaat acaagtattt aaaaggggtg
   145201 taagaattat gaaagcatta gaatttttga acaaggcacg agtttattat ttagcaacag
   145261 ttgatgagaa caatcaagca catgtgcgtc ctttaggatt tgttatggaa tacaatggta
   145321 aacttacatt ttgcacatct aatcaaaagg atatgtttaa gcaacttatt tttaatccaa
   145381 aggttgaact ttgttgtata gaccaaaacc ttaatactct acgtatttta ggtgaagcag
   145441 tatttgttac atcaaaagaa acacaagcta aggcacttga aataatgcca agtttaggtc
   145501 agatgtactc tgtaggagat ggtaagtttg aaatattctc tattgataag gcaaaagtta
   145561 gttgttgttc aatgagtggt aaaaagattg atgtagagct ttaattataa ttgaatcgac
   145621 atccatagtg aaaattaaga aaacgttatt actgaaatgt tgatagattt aatttaaatg
   145681 caataaaaag atttttaaat aatgaatatg taaaaatttt tagttattag atgtgtattt
   145741 caataatgat atactatttt gaataattac atactagaaa taagataatt aaaatttact
   145801 ttataatggg atagatttct tttaaaaaat attttaacta taattgattt ttatttaatc
   145861 tgaaaaaaat attatgacta taaaaaattg ctacttatta tttggatatt tttatatata
   145921 aataataagt agcatgactt tatacattaa taatgataga atataaatta atagataaga
   145981 tatgatttta aaaggagtga tataagatga gtaaatatag ttctttatgg gaatatgtta
   146041 agaaaaacaa tagtcaatcg tttaaattaa cttttgaaga aataaaagat attgctggga
   146101 tagagataga ccattcgttt ttgaaatata aaaaggaatt aaatgaatat ggatatcaag
   146161 taggaaaaat ctctttaaaa gagaagactg ttattttcga taaaattggt taagacataa
   146221 ataattacat ataataaaat aatttgtatt gatgattatt acaaataaaa aagggcgtag
   146281 cactattttt tagtgtcaca gccccttttt tgtttataat tatgtacatt tcacattatc
   146341 acgatataag catttttctt atgagaaaat taattagaat tatttttatt catatttaaa
   146401 ttatttaaat tgttttccca gttttttatc tcctttttaa cttcttcact taaagtatca
   146461 cttgaagata ttttctttaa tttatcattc aaagatttct tttgttcctc tgaaaggtct
   146521 gtttttattg taggatcaat aatatctatt acatctttta catcaaaatc aacaaatttg
   146581 cacagttctt ctagatgatc aattagaaaa tctagacctt catatgacca ttctttataa
   146641 tcttttccgt tttttaatag aaactcattc acttggtaat tctgatttgc taattcaaag
   146701 aatgaacctg aaggatccat tatatcattt atagagtttt catagttaac aatattaatt
   146761 tgtcttatta atttctcttt ttctgttaag ttgctataat tcttgttaac aaaagctact
   146821 aatccaaatt caaagtttaa aattgaatct ttacgttttt ttactgaatc ttctccaaat
   146881 tccctaagac cttctaaatt tttatcaatg gctttatctc taatctctat taattgttct
   146941 atacttaaac cttctaagtt tttaggtact atttcttcat tattcttagt aacttctttc
   147001 aatttattgt tagtattttt attattgaaa ataaatatag cagttaataa acttaaaatt
   147061 attactaaaa taattaaact tacatttttt ttacttaaca tattaaacct ccttttttaa
   147121 ataagtattg tacttgtgaa aaataaattt gtttatgaag ataacattta ctactgtttg
   147181 ttctaaagat tataata
//
LOCUS       DAMJXI010000003       138222 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.003, whole genome shotgun sequence.
ACCESSION   DAMJXI010000003 DAMJXI010000000
VERSION     DAMJXI010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 138222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 138222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..138222
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.003"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            116..307
                     /locus_tag="PC465_000291"
     CDS             116..307
                     /locus_tag="PC465_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HDF2647627.1"
                     /translation="MKKVALILAIIGALNWGAIGILGTDLIGSIFGGTYEMVSRIIYF
                     IVGLAGLYLIPSLMSDDRE"
     gene            462..1871
                     /locus_tag="PC465_000292"
     CDS             462..1871
                     /locus_tag="PC465_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2647628.1"
                     /translation="MFIINELNKIVNEEVISFHMPGHKKGQVYKKLGYKDILKNLYKM
                     DTTEILGTDNLHFPEGIIKNSQKKASRVFKSDYTCYLVNGSSCGIQSAIMSVCSPKSK
                     IITNRDCHQSVINGCILGDIDIEYVPCEISEETNILKGISISNVIDIIDKNLDAKAVL
                     LTYPTYYGMTYDLEYICNYAHSKKMVVIVDEAHGAHLGLSERLPKTALEQGADIVVQS
                     THKTLPAFTQSSMIHIQGDRVDIDKILNMLRITESSSPSYLLLSSLELAVDIYENKGK
                     ELMEELLNNIITFKNKVDSNINIYDTNDKTKIFISSKNMGLTGYELENILRNKYNIQV
                     ELSNYYGVLLICTIGNTAEDFSSLETALNNVVKEDFKFEKLENKKYPVVIPKKILTPR
                     EAFYKTKKSVKIYDSIGKVCGECIVPYPPGISVISPGEVISKEIIDYLMFCHSKGMIV
                     SGLKDVDLNFIQVIDLEDI"
     gene            2002..2691
                     /locus_tag="PC465_000293"
     CDS             2002..2691
                     /locus_tag="PC465_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HDF2647629.1"
                     /translation="MKGKLIIIESGSDASGKATQTEILYERLKKEGYMIKKVEYPNYE
                     SPSSALVKMYLKGDFGKNASDVDPYIASTFFTADRYASFKTDWEEFYNEGGIIIADRY
                     TTSNMVHQASKMDICDREEYLNWLADYEFNLFKIPQPDCVIFLDVPIEFSKKLMENRK
                     NKITGEEKKDIHESDIEYLEKSYNNALYIADKYDWKKINCVLDNKLRSIESIHNEIYK
                     IVLDSIKPMER"
     gene            2694..3629
                     /locus_tag="PC465_000294"
     CDS             2694..3629
                     /locus_tag="PC465_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HDF2647630.1"
                     /translation="MYFENIIGQDFAKKYLTNSIKKNKLNNAYMFEGMDGIGKKKFAD
                     ELSKLLLDYENLENSPDYVLIKPDGNSIKIAQIRNLQSDIVIRPHKDYKIYIINNAEK
                     MTVEAQNALLKTLEEPPNYAIIILVTNNKESLLETIKSRCDIIKFSPIPIEDLKRYLI
                     NTGIEEERAQLLAIFSRGSIENALNLSQSSEFSMMREDIQQYIQIMLDKNIVEILNIP
                     NNMEKYRGKIIALLDMMINYFRDIILLKENVNKNMLINVDKLVFIQNMSGKISYSQLS
                     KIIDIIEDAKSKIKSNCNFNISIQVMSLNIYEVIK"
     gene            3626..4519
                     /locus_tag="PC465_000295"
     CDS             3626..4519
                     /locus_tag="PC465_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HDF2647631.1"
                     /translation="MIKIVGIRFKSAGKIYYFDPVDFNIEQDMDVVVETARGLEYGKV
                     VVGPKDMDESELVSPLKPIIRIATEEDKKVYLENKEKAKETFELCQQKIKEHELTMFL
                     IDCEYTFDRNKLIFYFTAEGRIDFRELVKDLAAIFKTRIELRQIGVRDEAKSIGGLGP
                     CGRKLCCSSWLGDFQPVSIKMAKDQSLSLNPTKISGICGRLFCCLKYEHDVYSEAIEK
                     MPVVGALVQSDDGKGKVVEVNPLLEQIKVEFQDKTVKIYTREDIKILREPKKCDGCGG
                     KCKDNDGLDEATLRELKKLED"
     gene            4597..5343
                     /locus_tag="PC465_000296"
     CDS             4597..5343
                     /locus_tag="PC465_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HDF2647632.1"
                     /translation="MQLKDSERIDDLQLKGLKIIQDTNGFCFGIDAVLLANFTKIKKD
                     AKVVDLGTGTGIIPILIAGKSEAKKIIGVEIQEDVYEMATRSIKLNGLEERVEIINED
                     IKYIDKVLDINGYHVVTSNPPYMHIDGIKNPNDKKAISRHEVRCNLEDVIRAASRLVM
                     PRGKFFMIHRPTRLVDIITLGRKYKLEPKVIQFVHPRPQKAPNLVLVQFVKDGRPELK
                     ILDPLYVYGEDGNYTKELKAIYNNKDIGEL"
     gene            5344..6177
                     /gene="rsmI"
                     /locus_tag="PC465_000297"
     CDS             5344..6177
                     /gene="rsmI"
                     /locus_tag="PC465_000297"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HDF2647633.1"
                     /translation="MSGKLYICPTPIGNLEDITYRTLRILKEVDLIAAEDTRHSIKLL
                     NHFEISKPLTSYHEHNKDSKGDYLINKLIDGENIALISDAGMPGISDPGEEIIKQAIQ
                     NNIEIEVLPGATAFVTALVGSGMDTHRFVFEGFLDRDKKVRKAQLEELKEESRTIIFY
                     ESPHRLKDTLKDMLKILGNRNISINRELTKKYQEIIRENIETTIKIFEEKEVRGEFVL
                     IVEGFHGEKSKKENYDGLTDREYVLKLIESGMNKKDAIKIVCKDRKLKKDVVYKQVLD
                     L"
     gene            6200..6904
                     /locus_tag="PC465_000298"
     CDS             6200..6904
                     /locus_tag="PC465_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HDF2647634.1"
                     /translation="MEIGKIIIESLKREDTHKIFIELDNKHELEKIIPKISCMKSVGE
                     CKYHVVNCFEHSINALKELEIVLNDKDFFPIHLRKHVSNYLNTYIEEGINKLHVLKLG
                     TFLHDIGKPDSMTLDETGRVHFTNHEKIGAQIIDNMGIKLELSTETYRLISKYVRYHM
                     ILLSLYKKNDLSRKELINVFNLVDEDTIGVIMLGYADIVSTVKLLGKSGEVSVLKTYM
                     EYILTNYLYKSNYTHV"
     gene            complement(7092..7520)
                     /locus_tag="PC465_000299"
     CDS             complement(7092..7520)
                     /locus_tag="PC465_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HDF2647635.1"
                     /translation="MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEES
                     GVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLL
                     LKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL"
     gene            complement(7557..8987)
                     /locus_tag="PC465_000300"
     CDS             complement(7557..8987)
                     /locus_tag="PC465_000300"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HDF2647636.1"
                     /translation="MRNLTLLTDLYQLTMLNGYFEKNIHEDIVVFDMFFRKNACDGGY
                     TIVCGIDQVVEYIDNLHFSDEDLEYLKNLNLFSDKFLKFLKEFKFTGDIYAVEEGTIM
                     FPNEPLITVKAPLYQAQLIETALLTIVNFQSLIATKASRVCFAAQGDPVFEFGLRRAQ
                     GPDAGIYGARAAVVGGCAGTANVLAGKMFDIPIIGTQAHSWVQKFDNELEAFQAYADV
                     YPDKCLLLVDTYDVLNSGVPNAIKVFKNISEKGYKPMGIRLDSGDLAYLSKEAKKQLD
                     NAGFSDISITASNDLDEYTITSLKAEGATINSWGVGTKLITSFDSPSLGGVYKLAASC
                     EKGVLEPKIKISENPEKINNPGYKKVIRIYNEDNKAEADLIMLHDEVIDESKPLEIFH
                     PTYTWKTKVFTNYKVKELLKPLYIKGRCKYNKKAVLEIKNHVQYELSTIWEQYKRLSK
                     PHIYKVDLSRNLWYLKTQMIDSKKVL"
     gene            9119..9703
                     /locus_tag="PC465_000301"
     CDS             9119..9703
                     /locus_tag="PC465_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein A"
                     /protein_id="HDF2647637.1"
                     /translation="MIIIGKIWFYMVSIGIIGSLISKNMGELNKVILSETSKGIEFAI
                     SLAGIMALWMGIMNIAKESGLIEKIGQKLNPIMRRLFPSIPKGHKAMSYIVMNIALNM
                     LGAGNGATAFGLKAMSELQTLNNKKDTATNDMIMFMVINISSIQIIPFTIIKLRMDMG
                     AQNPSEIIFTTLFATIISTAVAIITCKFFQRRYR"
     gene            9719..10240
                     /locus_tag="PC465_000302"
     CDS             9719..10240
                     /locus_tag="PC465_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein B"
                     /protein_id="HDF2647638.1"
                     /translation="MEIFSNLLIPIIILYIVIYGKYKKIDVYDSFVKGAIDGLKAAWD
                     ILPYIIGIFLAIGIFKTGKGLDMLEWLFTPIANMMSIPKELIGLISVKPLSGSGALGM
                     YSELANRVGIGSLVEKMGATIVGSSETIFYTMAIYYGSLKIKNTRHTLSCAMISHVAG
                     VIAAVFICYVIFV"
     misc_binding    10306..10552
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10636..12573
                     /gene="metG"
                     /locus_tag="PC465_000303"
     CDS             10636..12573
                     /gene="metG"
                     /locus_tag="PC465_000303"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HDF2647639.1"
                     /translation="MSKPSFYVTTPIYYPSGGLHIGHTYSTVAADTIARFKRFCGYDV
                     KFLTGTDEHGEKIQKKAIEQGMSEIEYLDGMIKDIKALWNTMDISYDDFIRTTEKRHT
                     DIIQKIFTKLYEQGDIYKGEYEGRYCTPCESFWTESQLLEGNKCPDCGRETYLVKEES
                     YFFRLSKYEDRLKELFKDDSFCFPAARKNEMVANFLDKGLEDLSVTRTTFDWGIKVPF
                     DEKHVIYVWVDALCNYITALGYMTDNDEEFKKYWPANVQIVGKEIVRFHTIIWPALLM
                     ALGLEVPKQVFGHGWILFADDKMSKSKGNVVYPEPIIERYGIDTLKYFLLREFAFGQD
                     GSYTHRNFVTRINYDLANDLGNLISRTVAMVEKYNNGIIPTAKVSTNFDADLKEQAVS
                     TRENFEAEMDKMQFHEALESVWKLVRRTNKYIDETMPWALAKDETKKDELDTVLYNLC
                     ESIRIIATLINPIMNETANKIYEHIGIKGQDDITTWESTKTFGLIGENVKVFKGEPLF
                     PRLDVEKEIEELTKMFSGKPPVEEKPLEHKEEITIDDLDKIELRVGKIISCEKHPKAN
                     KLLVSQVKIGPETRQIVSGIAEYYKPEDLVGKEVTVVCNLKPVKLRGVESQGMILAAG
                     DDGDPYVLPFTQGAKDGCEVR"
     gene            12603..13373
                     /locus_tag="PC465_000304"
     CDS             12603..13373
                     /locus_tag="PC465_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HDF2647640.1"
                     /translation="MLFDSHAHLNDESFDEDRDELIGSLKDKGVDLVVNPGADIETSI
                     TAIELSKKYDFIYSAVGVHPHDVSKLDDTAIETLRKLATENEKVVAIGEIGLDYYYDY
                     SPREEQKEWFKKQIELANELKLPIIIHDRDAHGDTFEIIKNTKNPEIGCVLHCYSGNV
                     ELAREYVKMGCYISIPGTVTFKNNKKTREVVREIPLERLFIETDSPYMSPEPHRGKRN
                     NPSQVSFVADKIAQEKGISYEEVCRVTKENAKKFFNIK"
     gene            13711..14142
                     /gene="phnG"
                     /locus_tag="PC465_000305"
     CDS             13711..14142
                     /gene="phnG"
                     /locus_tag="PC465_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HDF2647641.1"
                     /translation="MYTVDSTKILINMNLEKLEKIYSMIKDTSSISIIKEPNLATVMV
                     RANESVKNTTFNLGEILVTECSVKVDESLGYGIVSENNNKKAIYLAVIDAVLHSNNSK
                     FDELKNYINKSVYEENLRYEQEIIDEFSLINKTKVQFNAMD"
     gene            14157..14732
                     /gene="phnH"
                     /locus_tag="PC465_000306"
     CDS             14157..14732
                     /gene="phnH"
                     /locus_tag="PC465_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HDF2647642.1"
                     /translation="MVNYTQEIYRKMLDSASFPGKLNNIDNINIENNTKLLNGAIGIA
                     ITLLDQEVTFYIENYTQKDIKNIRALTMSNQIDYRKSDYIFLDINSEVDILQIKIGSF
                     EYPDESATIVHQVNDLSTYSQTKYIKLDLSGPGIKSKNSIYINGIREEFIERLSSINK
                     DYPIGIDLILVDKKGEIAFIPRSSKLSWEVL"
     gene            14735..15820
                     /locus_tag="PC465_000307"
     CDS             14735..15820
                     /locus_tag="PC465_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-phosphorus lyase complex subunit PhnI"
                     /protein_id="HDF2647643.1"
                     /translation="MAYVAVKGGEEAILQAKNILEFYRVKGDSLPIDVKQIEEQMSYA
                     VDKVMSEGSLYNKELSALAIKQAQGDILEASFYVRALRSTMPRITYSEPINTEEMRIK
                     RRISATFKDIPGGQYLGATRDYENRILNVELLEEDEKKNRDFRDSFINELETVDEIPE
                     FTKISNIFRKENLLQEEVCENKLEEVIDDITRNSLRFPVSRSAKLQALTRGESGVVSG
                     FAYAIVRGFGDEHPYISELRTGNVFIKVKHPIYEDEEIIIGDMLVTECEIVSKASQNK
                     TENSKTNSEDKNKMSLGYGLCMGNNENKAISMAILDKSLEPNSEKLAQDEEFVLLHID
                     GIDSLGFISHFKLPHYVDFKADVERIK"
     gene            15840..16709
                     /locus_tag="PC465_000308"
     CDS             15840..16709
                     /locus_tag="PC465_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HDF2647644.1"
                     /translation="MIYNYGFLDENTKKEIRRKILKAISIPGYQVPFGSRELPIAKGW
                     GTGGLQLTLSLIGKNDVVKVIDQGSDDSTNACNIRSFIASVSNVETTKDTLEATLIQT
                     RHRIPEEKLKSNQILIFQVPIPETLRIVEPSEVETRRMHSEEDYSRMWVYLYEDIVRF
                     NDISIAVEYPCKVNDRYLMNPSPIPRFDIKKLNMSDNLFLFGAGREKRIYAIPPYTKV
                     EPLEFEDYKFEEEKFEGKYCSLCNSTNTFLDEVYDSDTNEKYYSCSDTSYCEKVRLKN
                     NSIDVTIGGTWNE"
     gene            16702..17568
                     /locus_tag="PC465_000309"
     CDS             16702..17568
                     /locus_tag="PC465_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2647645.1"
                     /translation="MSKINDSKRLENIDKQVLIGRNINLIYGDGCEKCFESTGYESNN
                     ICKYCGSIVACNNVNLELYEGEVLGIVGESGSGKSTLLKILFFQEHANSGEVYIFHYN
                     KDTNILELSDQKKRYIKNHFMGIVYQNPHLGLNLDFSSGGNIAEKLLMANLYNVEKIR
                     DRGKELLIKTNIPVERIDHKPKYFSGGMQQRVQIAKALSNNPPILLLDEVTTGLDVSV
                     QAEVLDLIREIQRELKISMIVVSHDFDVIKMLADRTIVMKNGSVIESGLTDQIMEDPQ
                     HPYTQQLINSLL"
     gene            17609..18322
                     /locus_tag="PC465_000310"
     CDS             17609..18322
                     /locus_tag="PC465_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2647646.1"
                     /translation="MKETILEVNNFSKDFELHALNKTITACSNISFEVSKGEFLGIIG
                     KSGAGKSTILKSIYKTYIPTTGEIIFNSEIYGNVDLAKIGDREMINLRKKEIGYVSQF
                     LKTLPRITAIELVVHSLIESGFEKDCSYDMAKDILNQFEIKENLWDAYPNNFSGGEKL
                     RLNLAQAMVKKPRLLLLDEPTASLDNQSKIYVKEKMLELKSQGTTMIGIFHDIEFMET
                     VIDKTFTMAKGTISESGVA"
     gene            18323..19492
                     /locus_tag="PC465_000311"
     CDS             18323..19492
                     /locus_tag="PC465_000311"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HDF2647647.1"
                     /translation="MIKLIHNANIVLEDMILENGHLIIEGDTIKKVSNDKIDYAFDFN
                     EIDEIIDAKNLYVIPGIIDIHSDAIEKEIEPRPSTLLPFNMAFYELDKKLPSNGITTV
                     YHSISLGDGVGVRSIDNSLKMIKNIDSYKNIDSKSINHKVHLRYEVLYYEGLEKVLEL
                     LDENKIDYLSIMDHSPGQGQYTNPTFYKEYATKVWGVTENYVDTWLDDLVNLHDNLDW
                     NKIANIIGIAKTKNINVASHDDDTLEKMDFIKNIGINVSEFPITLEVAKHSKKLGVLT
                     CLGAPNIVRGKSHNNNLKAMDAILEDCCDIVCSDYLPSAMIKSMCIVAERINNLNKAV
                     SLFTSNPAKAVGIYDERGSIKENKKADLVLVDIDSEYPKVVNTIVNGKTVYKREV"
     gene            19496..20332
                     /locus_tag="PC465_000312"
     CDS             19496..20332
                     /locus_tag="PC465_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HDF2647648.1"
                     /translation="MLTELHCHTSISDNNFTTEEIIKKAAEKNINILAITNHDTLSGL
                     DEALVLGEHYGITIIPGIEISAYDYKNRKRVHILGYNIDLNSQEIKNLCNPMVCDRHK
                     ASVKMVNKIIDLGYKISLEDVKKYSSKTGIFKQHIMKALIDKGYTDNIYSSLYKELFH
                     RGNGKVYVSLKYVDYRDAIKAIKNSGGICVLAHPGQMDNFSAIEEMVKVGLDGIEVYH
                     PSHNKELEKESLSYAKKYNLVVTGGSDYHGFYSQHNYELGSKSLNKEDLFKFRLALGG
                     VL"
     gene            20333..21328
                     /locus_tag="PC465_000313"
     CDS             20333..21328
                     /locus_tag="PC465_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2647649.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHGGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSNIDKKVKEVLEVVELSGYEKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIRSLHRKLGITTIMVTHDQEEALCLADKMVVMNRGEIIQVGTP
                     KEVYKNPETPFVADFIGTINFIDDGINKIAIRPEDIKVESNRDSKDKDIKVGEILDIE
                     FRGFNYRITVEYRSKQMKLDVVSKVAEQMKLCIGSKINFKIPKEGIVQYKSEGCA"
     gene            21346..23034
                     /locus_tag="PC465_000314"
     CDS             21346..23034
                     /locus_tag="PC465_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HDF2647650.1"
                     /translation="MITSKNKRRISDSTIQKYFLIFSVIVLIVFILFPLVSLLKNAFM
                     DTSGNFIGISNFSKYVENPSLIASFKNSIFVSTVSSLISLCLAFIYSYAITRTNIKFK
                     DFFKTMGMFPLFAPTMLYGISLIYLFGNKGIFTTMGLEVPLYGPLGIIISQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFCKITIPGIKYSLLSSFFVSFILAFTDF
                     GAAKVVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTLDKMASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIVCSFITLLIFILIFVSVIGSVIKLWPYNLSFTMEHY
                     TFKGILGSGIKTYLSSLKISTLTAIFGTIFVFFSAYMIEKVDKFPKLRQTAYLLSMIP
                     MALPGLVLGISYITFFNSASNPLNFLYGSTAILVIVNVVHFYSVCFITSNSSLKMLDK
                     EYELVAKSINIPFYKVFFNITVPMSITSILEIVVYYFVNSMVTVSALIFLYTPQTQTA
                     SISILKLDEIGYIGPSAAMAVLVLLTNIIVRLLYEFVTKKLKNNTQKWQQKDVA"
     gene            23046..24113
                     /locus_tag="PC465_000315"
     CDS             23046..24113
                     /locus_tag="PC465_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2647651.1"
                     /translation="MKFKKLVSLGVLSTLLLSVITGCSTDSSGSDSKSDSKTKGDLTV
                     YTAIEEDSIEPYLATFKEKYPDIKLNIVRASTGDITARLLAEKDNPQADVVWGVAATS
                     LLVADDQGMLEPYAPKGSEEIESAFKDDKEVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPSSSGTGYLTVSALIQIMGEEKAWQYMDKLHENIGVYT
                     QSGSAPATSAASGEYPIGISFGYRGIKLKEEGYPVEVVFPKEGSGWDIEANALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNYAVTTISTGNPIPEGFPKKPLEQMIDNDLKSAAK
                     NREDILNKWISKYDGKTEKES"
     gene            24597..24713
                     /locus_tag="PC465_000316"
     CDS             24597..24713
                     /locus_tag="PC465_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter ATP-binding protein"
                     /protein_id="HDF2647652.1"
                     /translation="MDDDINMIAIRPEDIRVEFNRDFKEIIDLKLRPYRYKN"
     gene            24877..25944
                     /locus_tag="PC465_000317"
     CDS             24877..25944
                     /locus_tag="PC465_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2647653.1"
                     /translation="MKFKKLVSLGILSTLLLSVITGCSNVSSGSNLKSNNKTKGELTV
                     YTAIEEDSIDTYLATFKEKYPDIKLNVLRLSVGGITARLLAEKDNPKADVLWGVAATS
                     LIILDDKEMLEPYAPKGFDKVNPAFKDDKKVPSWVGIDAWMTGITVNTKELKAKNISA
                     PSSYEDLIKPEYKDLISMPSPASSGTGYLTVSELIQIMGEEKAWQYMDKLHKNIGVYT
                     QSGSAPAILAASGEYPIGISFGNRGIKLKGEGYPVEVVFPKEGSGWEIESNALVKKDN
                     IKEAAKVFLDWAISKDAMNEYSKNFAVTTIDTGNPVPEGFPKNPLEQMIDNDLKSAAR
                     NREAILNKWIEKYDGKTEKES"
     gene            26136..26666
                     /gene="rnmV"
                     /locus_tag="PC465_000318"
     CDS             26136..26666
                     /gene="rnmV"
                     /locus_tag="PC465_000318"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HDF2647654.1"
                     /translation="MIKEIIVVEGRDDVTAVKRAIDAELITTGGFGFPKGVMERIKAA
                     NERRGVIIFTDPDFAGEKIRKKIASEVPGCKHAFLPREEAKKDGDIGIENATPQSIIA
                     ALNKVRTENTEKRYEFKQVDLIRNGLIGNEEASLRRDALGKILGIGYGNAKQFLNRLN
                     NYGVEREEFIDALKQI"
     gene            26837..27706
                     /gene="rsmA"
                     /locus_tag="PC465_000319"
     CDS             26837..27706
                     /gene="rsmA"
                     /locus_tag="PC465_000319"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HDF2647655.1"
                     /translation="MDRLSSHNATKEVVQKYNFKFSKSLGQNFLIDSNIIDKILSGAR
                     ITRGDNIIEVGPGIGTLTREMGKIAEKVVAIEIDRNLIPILKDTLSDLDNTEVVNQDI
                     LKVDIQELVKDKLNGGPVKLVANLPYYITTPIVMKFLEEDIPVTDIVVMVQKEVADRM
                     NAIPGTKDYGALSIAVQYYCDTEIVAKAPRHMFIPQPNVDSTVIGLHVRDKRKYDVHN
                     EDIFFKTVKASFGQRRKTLLNSLGGLGFLNKDEIREVLKEANIDEKRRGETLSIEEFS
                     VLSNIINTKVSSK"
     gene            27772..29034
                     /locus_tag="PC465_000320"
     CDS             27772..29034
                     /locus_tag="PC465_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647656.1"
                     /translation="MGSKRKFKRDYIILEAKDINFRYKERVLPKAFAKVEVNDEKAII
                     ALYVENLKYVKDGYKAVAIKDDHGLIDLGNIILNEQGRGEFVLDLEDYDDEIKGIALL
                     YERNIPLIGFKGNKLENYEDILFQEVEEEEYEEYEELEEEDEEIEDNEESDRDEGSEE
                     EYIIEEYDEDEYEDYWEDDEDIEEGELKARTEVEDSSDEEIEEFNNYKEIENYNRVKV
                     QEEYIDIEYDEEEEEEEVFEVNREEDRFVSSKPTKSKKVQKDQNNIEKIKRANGVSQG
                     ESGNKQTSTLLMPRQIKKGLKLFKEVKPFVTDYIDKTRWWKIEINPTTLCGYTMPYLG
                     YLNVLNYTMYSDAVLHSYKYRHYLFGVQYDEYNKRKHYIYAIPGNRNEQPDNGSTGFL
                     RYQACDNRTNSLGYWLCFIDSRQRNIVR"
     gene            29185..30300
                     /locus_tag="PC465_000321"
     CDS             29185..30300
                     /locus_tag="PC465_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF2647657.1"
                     /translation="MINEQRILNEFLELVQIDSLSLKEGNVAKVLVKKLEEIGCSVVI
                     DNAGEKANGETGNIIATLKGNKEGKKILFSSHMDTVTPGIGVKPIVDEANGIIKSDGT
                     TILGSDDKAGIAAILEGLRYINENNIEHTDIQVVFSICEECGLVGAKNLDYGKIDSEY
                     AFILDSGGSPGEIIVKAPAQDVINVKILGKTAHAGLEPEAGISAIMVAARAIENMNLL
                     RIDEETTANIGIINGGTATNIVTGEVNIIAEARSLKENKLDVQTKHMVETFEKAAKDF
                     GAQIEIDVNRAYTPIDVSEDSEIIKLAKKAFSNLGIEGHTESTGGGSDTNILSKNGIE
                     AITLGIGMKNAHTLSEHIAIKDLYDSAKMVVEIIKEA"
     gene            30486..31382
                     /locus_tag="PC465_000322"
     CDS             30486..31382
                     /locus_tag="PC465_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF2647658.1"
                     /translation="METRYEEANKITIQSILWNIVLTIIKVIAGVIGNSSAMIADGLH
                     SASDIISSIGVLIGNYVSSRPGDREHNYGHEKAETLVSFVLSILLIFVSITIGIEAIK
                     SLFNLDALSVPSILPLVVSVISILIKEYQYRITIKVAKKINSPALKADAWHHRSDALS
                     SVAAFIGIGGSILGFKPLDPIASVVVAIFVAKVGISILISSVNELMDVSVDEEEIKEL
                     KFIVADTEGVKNLGDIKTRKHGAMAYVDLTICVDENLTVKQGHDIATKLEKHIIKHME
                     FVKGITVHVEPCTNCQGNKCNN"
     gene            31452..32249
                     /locus_tag="PC465_000323"
     CDS             31452..32249
                     /locus_tag="PC465_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647659.1"
                     /translation="MSKKRKLKKKAAILIGVVVFFIIYFISFRIGINMEKDKSEVPKK
                     VEKEEEDNRSLRTQIKEKKKVYISDKNIENIKIEEDMWDEIKLFFSDFKKVRNTTSSY
                     EAVYEGYSDDGVKFSTDLNFFRVYTVNKEEYYKVPVSSKDAFKKLLDESIYTSFDLLS
                     HYKDWKEVTITHGKEIKKVHRWKFDDLAHKMISKRVVGKVQPEKSKERSDYNFTINIK
                     GDNFDVKVDTMGKDYVKVTSKKNVSYYEVHTSLFDYLKNEIFEIGKK"
     gene            complement(32304..33656)
                     /locus_tag="PC465_000324"
     CDS             complement(32304..33656)
                     /locus_tag="PC465_000324"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HDF2647660.1"
                     /translation="MNIHFIGIGGISMSALAEICINKGYQVSGSDSNESYLLDKLRDQ
                     GATIYIGQKKDNISDDVNMVVYTAAVHPDNEELVAAKEKNKLVMNRATFLGQIMREYK
                     NSIAVSGTHGKTSTTSMLSTIFEYADLDPTILVGGNLSMIGGNVKIGNSNHFITEACE
                     YVDSFLNFNPKISIVLNVEEDHLDYFSGIDEIKASFNKFGKLLPPEGYFIINGDDENI
                     DDILYDVKATIIKYGRDSDNDAVIKDIHFDNSGHGIFRIEYEGRDLGEFELSVYGLHN
                     IYNASSAIMAALVSGIDLETIRKNIKIYKGVGRRFETKGYYKNALVVDDYAHHPTELK
                     ATLAAAKKLKKSTLWCIFQPHTYTRTKSLLGEFSEAFYAADKVIITDIYAAREKDPGD
                     IHSKDLVEKLYQNNVDAIYIKEFEDIVKYLRENVKDNDLVITAGAGPIYKVADLLVEK
                     "
     gene            33875..34753
                     /gene="purR"
                     /locus_tag="PC465_000325"
     CDS             33875..34753
                     /gene="purR"
                     /locus_tag="PC465_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HDF2647661.1"
                     /translation="MKFKRTERIGAIVKILSDNPNKIYTLSYFTNQFNAAKSTISEDL
                     LVVKNVFEKLHLGKVITISGAAGGVKYIPKTSIAENAEFLMELCERICDKSRILSGGF
                     LYLIDLIYDPTIAAKIGKIFASNIEYVDADYVVTMETKGIPMALMTAKAMNLPLVIIR
                     KDIKVSEGPTLSMTYVSGNSSKVESMSLPRKALKPDSKVIIIDDFMRGGGTIKGMVDL
                     MNEFGAEVIGTGVFISTTNPSEKMVKDYISLIQLDVNGDKIVVEPNLKTFKDEYRNED
                     LDEEEDSEFEFEIDED"
     gene            34909..35187
                     /gene="spoVG"
                     /locus_tag="PC465_000326"
     CDS             34909..35187
                     /gene="spoVG"
                     /locus_tag="PC465_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HDF2647662.1"
                     /translation="MKITDVRVRKLTEEGKMKCIVSITFDNLFVVHDIKVIEGHNGLF
                     IAMPSRKVGEGNFRDIAHPINAEMRQVLEDAVLQAYHEALVQWEVAAE"
     gene            35400..36779
                     /gene="glmU"
                     /locus_tag="PC465_000327"
     CDS             35400..36779
                     /gene="glmU"
                     /locus_tag="PC465_000327"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HDF2647663.1"
                     /translation="MNFKAIILAAGKGTRMKSKYPKVIHKVCGKEMVNHIIDVSKKSG
                     VKDTVVILGHEADVVKEKLAEEIIIAMQTEQLGTGHAVKMAKEYINDEDTIVVLCGDT
                     PLIKEETLKRLFEYHIENKYHATVLTTRVGNPTGYGRIIRDKKGDLLKIVEQKDANSE
                     EKMISEINSGIYCFNGKSLREALDLLNNNNSQGEYYLTDTAKIMRDKGLKVGAFAGST
                     IEELMGVNSRVELSKAEEIMRRRINESHMVNGVTIIDTNSTYIESDVMIGNDTIIYPG
                     VMLQGKTRIGSDCIIGMNSSITNSEIGDGTEIKNSTIIDSKVGENSTVGPYAYLRPKS
                     DLGNNVKIGDFVEVKNAIIEDGSKASHLSYIGDAHVGKNVNIGCGVVFVNYDGKNKFK
                     SIVKDNAFIGSNSNLVAPVVVEEKGYIATGSTITHDVPDGALAIARERQVIKEGWVEK
                     KNQKDDQSK"
     gene            36874..37824
                     /locus_tag="PC465_000328"
     CDS             36874..37824
                     /locus_tag="PC465_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HDF2647664.1"
                     /translation="MNTSGSEIKIIAGNSSKELAQKIADYIGVSVLDCEVGTFSDGEI
                     CVNMNETVRGCDVFVVQSTNSPVNDNLMELLILIDALKRASAGRITAVIPYYGYARQD
                     RKAKARDPITAKLVANLITAAGADRVLTMDLHAAQIQGYFDIPLDHLLGGTILANYFN
                     EKKIEDLVVVSPDLGSVTRSRKFANTLNGEVPIAIIDKRRPKANVCEVMNLIGDVKGK
                     NVILLDDMIDTAGTIVNAANALKEFGAKDVYACCTHGVLSGPAIERIANSEISELIVL
                     DTIQLPEEKRIDKIKIKTVAPLFGDAIRMIFSNESVSKLF"
     regulatory      38668..38753
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            38915..39436
                     /locus_tag="PC465_000329"
     CDS             38915..39436
                     /locus_tag="PC465_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2647665.1"
                     /translation="MKLKKNKKGFTLVELLVVIAIIGILAVVAVPALFSNINKAKVAS
                     VESDYSSVKSAALSYYSDTNKIPVTPDGQTGLSVLETYMESLPDKADIGGEYKLIKVG
                     SKLVLQIGTNTEGVTLTEAQSAKLLSDIGEKKIYTSATTNSLGDPLTSNTKIDNKVLY
                     IVLIDNTVMDTTK"
     gene            39588..41264
                     /locus_tag="PC465_000330"
     CDS             39588..41264
                     /locus_tag="PC465_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HDF2647666.1"
                     /translation="MAKKVRIGDKLVEKGYITEEQLKWALSEQKNSGKRLGEFLVQEG
                     LIDSNLLISVLKELLDIESIFLEGTEIDTLATKMVPENICKRYTVFPFKIDGNKICLA
                     MSDPQDREAVQDVRRMSGKDVEIFISSTEDINKAIGHAYAHSEINKAMTEYNKNRTGG
                     VRETVILEEDVNAAPIVRLVNNILENAVRMEASDIHIEQSENYMRVRFRIDGMLREYM
                     RMNSAPYKAVISRIKIMSDINISEKRIPQDGRIYLKVDNKPIDFRVSTMPTNRDEKIA
                     MRVLDKSNFMVSKEVLGIDEHGSKIYDELINTPYGLILVVGPTGSGKTTTLYSMLNQL
                     NTENRNLLTIEDPIEYELPGVNQSQINEKAGLTFASGLRAFMRQDPDIIMVGEIRDTE
                     TAEIAIRASLTGHLVLSTLHANTAVGAISRLLDMDVESFLITSSVLGVISQRLTRKIC
                     EHCKVSYEADIGEKKALGIDVNESVTIYRGKGCERCNNTGYKGRLGIFEMLEITPEIK
                     ELIDSSANQREILKMARKQGMVSLKEDIVKKVLNGKTTVEEMIRIILMTD"
     gene            41276..42484
                     /locus_tag="PC465_000331"
     CDS             41276..42484
                     /locus_tag="PC465_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HDF2647667.1"
                     /translation="MKSFKYTVIKEDGKKQTDVIEANDFNEARNLLRKRNLRVIEIKE
                     SKNKNIRLSSRKRKKDLGADQISHFCRQFAIIVSSGINSISGLETLARRSTNITLREE
                     INRIVAEIKVGSTIADSMLSSKSKFPKLLGAMVATGEATGKLDEVLKSMASFYASEHR
                     VKQKLRNAATYPLIVLISSFIMIFIFTTFMVPKMINSITTVGATLPLITRIVMGFGMF
                     MKKFWIIVLLVIILFIYQFKKYLKTSVGRAHKDRVINKIPVLGKGINCMVATRFSRAL
                     YLFVSTGYPLVQGLDYIIDSVNNTMAEKILASAKDGITRGEGLAENLERYTYFDSVLV
                     QMIAIGEQTGELENISRQMAEFYEYESEIYLNRMASMIEPVLIIAVGIIVAILVVSIF
                     MPMLSIYDAM"
     gene            42499..44211
                     /locus_tag="PC465_000332"
     CDS             42499..44211
                     /locus_tag="PC465_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HDF2647668.1"
                     /translation="MNKVYVSYYGDSISIVEGRYKHDKDKFYVKNFNVFSIEDIAQDF
                     SKEKYALLRYALENVKLKSRHVVFCLNTRDVILKPQKLPNMDKKDLDGFMKLEMDEMM
                     ALESDEYVFSYEVSSETPDNSDGDESSLNLIIGAIQKEEVNAIVEIMHEFDLVLDRID
                     TLSTAYLRMLKNLDYNDIMVTNISDNSTIINIYKKDTLFISDNIPIKITAKDMDMQLL
                     NVVEESKGLMNYYSSRNFGKVTDTILILGKRYSNKLIYETFSSAFSSYVSQGLTEIMD
                     ISDMITGDIDEDDINSIVELLGSMIEPKGKRDFENINFLPMDILRKQIKAKQMKNILK
                     IAPIVILILAIPYLCLIFSNNLANKELENVNGEIRNIESAYYQIGNIEKMIQSKSEEI
                     KVYDMLIGKKVKWENLLDDIDKNTPSKVELTSLSTTYQNLGTNNKADNSKSNKTTTDK
                     SSNNETKSSTKSDSNGDKTDNDLNEDKTTNVSEALTGNSETNSNNTDKDDKTPLYDKI
                     PNVINIEGNAKDSSYVGQFLYKLKGLYYFKDVKLHSIKSNAEDSNYTFSMTLYLKEGV
                     LTNE"
     gene            44204..45112
                     /gene="pilO"
                     /locus_tag="PC465_000333"
     CDS             44204..45112
                     /gene="pilO"
                     /locus_tag="PC465_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HDF2647669.1"
                     /translation="MNKDIFKKDIKDIFKMEVSLKGILIKVIILLAILSYGYFGLYPQ
                     YQKYIATKNSVKQATEKLNIYKEKTALMPKYEKQLEEVESELKEKSKNLLYDMQDGLF
                     LIGLDKKMKAYNIDLTSYDVGNVKEYEHFYGISTTISVRGDYRNVKKLMAYLEEQKNV
                     TQILDYTMTSYIEPEKEEEETTNNKDLIKNVNINKDTKIYWVEGENKWHLYKDCPLIK
                     EGEIIKNDKLLDRSTNYLCNTCVLRAATEKEAKKEVVAPKAEGVVDATFKFIMYTKEN
                     TTMILDTDNPSSWRPGKYNPFKSSAK"
     gene            45139..45705
                     /locus_tag="PC465_000334"
     CDS             45139..45705
                     /locus_tag="PC465_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2647670.1"
                     /translation="MSLYKNNEKGLTLLEVIIAVFILTIVLSISYKVFNGITSAVKKQ
                     QIITDAQVNINLINKYLNRDLENCKELTKTGSGNNYEYNIEMPDNVVKYEVSIETKKN
                     TEVYSVTRIQNNTIDTENEVREEIIYNQPLVQNNKEMKETPFKIEKQTGKSIYTVSIY
                     YNESVQESHKNSNLNNKTYTFDVMSRIG"
     gene            45742..46269
                     /locus_tag="PC465_000335"
     CDS             45742..46269
                     /locus_tag="PC465_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2647671.1"
                     /translation="MSKKNSERGFSLIEVLVAMAIMGIVLFAFFNIINTNNKANTKND
                     TDITSLNYVQSEIENLREKIKSGEFDFDSLDKLEDGTVVYEKLIDKSKKVVYDKVLSE
                     GDVSLYDTPYEKITTIKDEDGNLIDKGNITNKIKTIVEDKSGQIYKIAVTGKSMNDYS
                     SKKEVKIVTEIFKDK"
     gene            46290..47828
                     /locus_tag="PC465_000336"
     CDS             46290..47828
                     /locus_tag="PC465_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647672.1"
                     /translation="MRKWNKFKSERGAALVLVLVVVALLSIVGLIFSNQIANRIKSTK
                     TTNEGIQAKYLAETCVENSIDKAYEKLYDELEKMDNEFKSENQEKSISRSKLRNISDE
                     DFNNQDEENIEAERLGYMNNINFYLNKASSDLEKASMELKKLYDLDMLDYRDIEYVDA
                     NIISHRDSILEICKNYTSGDISKINEYILKEDIDSTTLIEAKLVNNDILLKMFLEENK
                     IENEHLNSAFSHTYKALDNISLAMQNMIEYRHTFHIDEPKVEVSNGIPDSQQYYELIQ
                     NPIINSMEYSWNSKWDTLENLLEILPNQTQGFNSLRVHLRNNVRKFEKLSDNISSGKK
                     NTAKNFLKYKELLYEISDQCNQLKSMSYEKIPVKYDNMALITTFDYIQNELLAEIKCR
                     LKELKPQEIDKTEGITIKIPFYKADYDMTKEGWPKLKENGSGAELSLMVTGDKNGIKE
                     VEVTDGKKNIIGLGVEENSNSKYKVDAIVNFNLNIDTNVVGNYDIKDKILINHDISSY
                     KKVN"
     gene            47928..49010
                     /locus_tag="PC465_000337"
     CDS             47928..49010
                     /locus_tag="PC465_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HDF2647673.1"
                     /translation="MYIYDLLEQGIRLNASDIHITVGTNPVARVKGGFVKLSEQILTS
                     EVTMQMAKDIAGESMFKVIEEHGEADFSASLKTGERFRVNAYRQKGNYAIAIRTITAE
                     IPTFEKLGLPESIKSFTEKHKGLVLVTGPTGSGKSTTLASMINIINEKQQKHIITLED
                     PIEYVHHHKQSLVNQREVGTDTESFHSALRAILRQDPDVILIGEMRDPETVSIALTAA
                     ETGHLVFSTLHTVGAAKTIDRIVDMFQPSQQQQIKTQLSTVCEGVVSQQLLPTADGKG
                     RIAAIELMFATPAIKNLIREGKTYQIPNMIQTGVKVGMKTMDQDLMELYKNGKITKDM
                     ALSRCTDQEFMTRMIGGVNYNGYYNR"
     gene            48991..49773
                     /locus_tag="PC465_000338"
     CDS             48991..49773
                     /locus_tag="PC465_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDF2647674.1"
                     /translation="MDIIIVNLYVFIVGIVFGSFFNVCIFRIPEGISISRPPSHCMSC
                     NTRLKPIDLIPVLSYLMSGRKCRYCYEKISSRYAIVELITGLLFLTVFMLYGISTSTI
                     YYLVLVSLLIIITFIDIDHFIIPDKILVFGAIFSMIFNLLFKEIPVKDSILGVFICGG
                     SVWIIVLLIEFVIKKECMGGGDIKLFAMLGLYMGVKNGLLTALLSVYVGAVYGICVII
                     ISRIKGKEYNSVIPYGPFISIGALITILSGKQLLELYFSMVI"
     gene            49875..50525
                     /locus_tag="PC465_000339"
     CDS             49875..50525
                     /locus_tag="PC465_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDF2647675.1"
                     /translation="MEYIIIISLFFAHLINKSLCVFCDREKKNLYNTFFIYIITVVLS
                     VLIYLKFGISVECVQYMVLIPFLIIISIVDYYTIYVYDITIVSGIIVQGIIFLAFFNI
                     AQFDYINHIFGLLIGFIIPYIIAKLTKGLGYGDVGLYSLCCFALGNNYGFYVIVLSFI
                     LAFLFFIILYITKVFKDVDIRKQIPFTPFISLSTILIIFTEYNIFNFYYNLLYKFI"
     gene            50539..51099
                     /locus_tag="PC465_000340"
     CDS             50539..51099
                     /locus_tag="PC465_000340"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HDF2647676.1"
                     /translation="MYVVVGLGNPGKKYEKTRHNVGFDVIDILAKEYNISVTKIKHKA
                     LIGEGRVGTEKVLLVKPQTYMNLSGETLIDIYKYYKVDLSNIVVVYDDIDLEVGKIRI
                     RKKGSGGTHNGMKSITKCLGSNDFPRVRVGVSKPEAGQDLADFVLSRFRKEESDNINE
                     ALEKAADAIDSIIRENIDMSMNKYNG"
     gene            51116..54502
                     /gene="mfd"
                     /locus_tag="PC465_000341"
     CDS             51116..54502
                     /gene="mfd"
                     /locus_tag="PC465_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HDF2647677.1"
                     /translation="MNDVFLYPLQNSKEYKDIINCIKNTKGSLLVNGLLPVQKPHISY
                     SIFNDLSRQMIFITSSDLEAKKVYEDLSFYMEDKVEYLGFQDIYFYHLDAKDRNEEAK
                     KLKVLLKLANKEKIILVTSIEAVLRKYIPKQVLLDSVSHYKVGDSLDLEKLTEKLVSL
                     GYERVSKIEGFGQFSIRGGIIDVFSLEYTNPIRMELFDDEIDSIRTFDVYSQKSIDKL
                     QQFSITPSREFIYPEKTTDALVKLKKETTKNTDEGTFQNIDYISSKTYFEGVENYIDY
                     IYPEENKSIFTYLADDAIVFINDITRLKERCENYINEFRENYKLNLERGLAIKNQGKL
                     LYHYTDLEYLVKDKSVVLNSLLPKSINNFSIKSIINFESREVPTFNGKVDLLVEELNR
                     LKYNGYKIILATNTLERANKLGKDLLDKGLETTISKDRDIEIKSSQVIIVPAHINSGF
                     QYKSIKFVVITDNEMIGVYKRASKTSNKKVKKGKKIESFLDLSVGDYVVHENSGVGRY
                     TGIEQITVNAIKKDYMKIVYQGGDNLYVPIDQMDKVQKYIGAEVEKVKLNKLGTNEWT
                     KAKAKVKKEIEDMTKDLIELYAKREKIQGYKFSKDTPWQAEFESLFPYQETEDQLKAI
                     EETKKDMESSKVMDRLVCGDVGYGKTEVAIRSIFKACMDQKQVAVLVPTTILAQQHYN
                     TFKERFENYPLRVEVLSRFKTPKQQKQIIEDAKKGLVDILIGTHRIISKDINLPNLGL
                     VVIDEEQRFGVKHKEALKKIKSTVDVLTLSATPIPRTLHMSLSGIRDMSVIEEPPQER
                     HPVITYVTESKESVIQDEIERELSRGGQVFFVYNRVEHIEEMASMIQKLVPDARVAVA
                     HGRMTSKSLENIILGFLNKDYDVLVCTTIIETGMDISNANTMIIYDADKMGLAQLYQL
                     RGRVGRSSRQGYAYLLYEKDKTLSEIAEKRLKAIREFTEFGSGFKIAMRDLEIRGAGN
                     ILGSQQHGHMAVIGYDLYVKMLNDAIKKVKGEPIVEEIDVEIDLSVNAYIPDNYIKDE
                     LIKIEMYKKIASIENKEDMLDIQEELEDRFSDIPKPVQTLLTIAYIKSLCKILKIEKI
                     RQLKDEILLVPITKYRTKQKIGYNIVTELEELLEKMCKVK"
     gene            54533..55528
                     /locus_tag="PC465_000342"
     CDS             54533..55528
                     /locus_tag="PC465_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2647678.1"
                     /translation="MKKVITLVIAMILVVSVTACSSSKGETVATVEGTKISSDEFKKT
                     IALYKDSMEQTYGKDIWDKEVEKGVKYKDKFKDLILDQLITTEVIYSQAKKDNLLPKK
                     EDVEKSFKELKDAMGKDEKYKEQLKKLGIDDEFLRDQQEKDLAMQNYQSNFAKKTKIS
                     DEEMKKYYDTHKDEFKKDEVEASHILLKTVDDNNKPLSDKEKAEAKKKAEEALKEVKS
                     GEDFAKVAKKYSQDTSASDGGKLGFFSRGQMVAEFEDAAFSMKKGEVSDLVETQYGYH
                     IIKVTDRINEQTSFEDAKETIKDQLLKNKYQEQIEKLTKEAKVEKDEKVINKITI"
     gene            55652..56191
                     /gene="spoVT"
                     /locus_tag="PC465_000343"
     CDS             55652..56191
                     /gene="spoVT"
                     /locus_tag="PC465_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein T"
                     /protein_id="HDF2647679.1"
                     /translation="MKATGIVRRIDDLGRVVIPKEIRKTLRIREGDPLEIFTAKDGEV
                     ILKKYSPIGELNEFSQEYAETLAEVLGYGVLITDLDSIIAVSKLPKKDYKEKSISDEL
                     EAIISERTVKYSKDKNILPLFKEDQKEYTSQVIMPIISASGDCIGSIVVVSKDKDTIA
                     ESEEKSLKIAANFLGKQVQ"
     gene            56311..57924
                     /locus_tag="PC465_000344"
     CDS             56311..57924
                     /locus_tag="PC465_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDF2647680.1"
                     /translation="MNNNKNKDSFLKGALILGLAGVIVKIMGGFFRIPLGNMIGSEGM
                     GYYQAAYPVYTLFLTLATAGFPTAVAKLVSEKVAIGNFKGANKIFKVSHTVLFITGII
                     SFCILFFGADYIVTNVMKNPGALYSMKAIAPALLFVPAMSAYRGYFQGRQDMTKIAVS
                     QVAEQFFRVVLGLTLAYLLMKSLGQTFGAAGAISGATIGSIASMLYLVFAYMLGRKER
                     RAEIDASQRFKDERVSYIFKKLLTVAIPITIGASVMPLVNMIDNVIVIRRLMEAGFTY
                     KVANSMFGQLTGMAMATINLPAVITTAMSMSLVPAISKAYALGNKSKARKDTKSAVKV
                     TLLIVLPCAFGMASLAIPIMGLLFPHEPSSVGTILFTLTPCVLFLGLIQTLTGIIQGM
                     GKPIVPVIALCVGMLCKIVISYTLTGIPDINVLGSAFGTVTAYFVAAMINLLYVKKHM
                     NVNFSKKEFIIKPFITVMTMFIMVKLSYGALVGFLGNSISTIIAICVGGIVYVVVILG
                     IGGIKKEEILTMPKGDKLYKLLKKVKLIR"
     gene            58031..59479
                     /gene="mazG"
                     /locus_tag="PC465_000345"
     CDS             58031..59479
                     /gene="mazG"
                     /locus_tag="PC465_000345"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HDF2647681.1"
                     /translation="MGKISIVGLGPGDYSLISQGVLESLINSPKVFFRTEKHPIIDKL
                     KETIQYTSLDYFYEKEENFDNVYLKISEFIIEESAKGDLVYAVPGHPRVAEKTVSIIE
                     RLANEKHIAVEILPSMSFVDAMFNYLAIDPSEGFKLVDAFEIENSYIDLDTSMIITQV
                     YDKFIASNVKLKLMEHYDYNQEVCIVNGAGVKDLESKKFIKLCELDRNENFFDYLTSL
                     YIPKSSKKMYNTVHDLEIIVNTLRSPSGCEWDKKQTHQSLKNSVIEEAYELCNAIDNN
                     DIDEMVEELGDVLLQVIFHCQIGNEEGYFDLKEVVNGICKKLIHRHPHIFSGAKLDMS
                     KFEKTWEELKKEEKGESTITDGLRRIPKHLPALMKASKVQHKAALVGFDWDNVEDVFK
                     KIEEEYQELLDEHRVGNIKYIKEELGDLLFSIVNLARFLDIDSGEALNCTTEKFINRF
                     DFIEKSAMNLNKKLEDMTLEEMDEFWNQAKKQ"
     gene            59568..59846
                     /locus_tag="PC465_000346"
     CDS             59568..59846
                     /locus_tag="PC465_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003153447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HDF2647682.1"
                     /translation="MNKAELVSKMAEKSGLTKKEAEAALNAFMSSVQDALVNNEKVQL
                     VGFGTFETRERAARQGRNPRDPEQVIDIPASKAPVFKAGKGLKDIING"
     gene            59918..60160
                     /locus_tag="PC465_000347"
     CDS             59918..60160
                     /locus_tag="PC465_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HDF2647683.1"
                     /translation="MRLDKFLKVSRIIKRRTVAKDACDKGIVTINGKVAKSSSEVNIG
                     DTLEIQFGEKKMKFKINEVKEHVLKNDAKEMYEILE"
     gene            60222..60476
                     /locus_tag="PC465_000348"
     CDS             60222..60476
                     /locus_tag="PC465_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YabP"
                     /protein_id="HDF2647684.1"
                     /translation="MEQNITLKDRSKLVISGVEHIYSFNDKRVELKTSVGEMVIEGEN
                     LDMSKLSIDENIISIDGTINSMVYAKPKKPQESFLKKVFR"
     gene            60477..61010
                     /locus_tag="PC465_000349"
     CDS             60477..61010
                     /locus_tag="PC465_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647685.1"
                     /translation="MIPFTQDVSIFYATIYGGILIGVLFDFYRGLRGNFKFINYFAII
                     FDVLFWFLATVIIFVTINLTEFFDLRYYHFVALFIGFILYYNTISKIVLSIINKIIRF
                     VRNSFKKVTHYIVSFLNNLYYVIIYSLHLLFDIIFYIPNIFIATRKSIKRKSNKKLKN
                     KKKSKPKKKKNKTKKRV"
     gene            61016..61300
                     /locus_tag="PC465_000350"
     CDS             61016..61300
                     /locus_tag="PC465_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HDF2647686.1"
                     /translation="MNLRKKFSGQIIVISLFLGISIFSMMTGFVFEYTKAKEYKKEIA
                     SLNKQLKKTEIQINSLKKDEKSYEGDLEDIARKRLNMVKPNETVYVDINR"
     gene            61413..62333
                     /locus_tag="PC465_000351"
     CDS             61413..62333
                     /locus_tag="PC465_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA family phosphatase"
                     /protein_id="HDF2647687.1"
                     /translation="MKVGAIDIGTNSMRLLIADYRDGNFINRKKFVNTTRIGYGVDSK
                     GYIKEDAIKRNIKALKEFSDKCNDEKCEKIYCMGTSALRDSKNGDYFVKLAKEETGID
                     VDIVTGIEESNLGFKGVLEGIQGDDTIIVIDIGGGSTEFIVGDSEGIIFNKSENVGAL
                     RMTERFLKHDIIEDEEFEAMSSFIYGEIDKTLNHIKDRGLKTLIGIGGTITSLSAMNQ
                     ELEIYSMEKIHNSKIHKKEIEEILQKLIKMTLSDKKNLKGLQEKRADIITAGVKILNI
                     IMEKLEIEEITVSEYDNLEGLICQKSKKMY"
     gene            62423..64795
                     /gene="spoIIE"
                     /locus_tag="PC465_000352"
     CDS             62423..64795
                     /gene="spoIIE"
                     /locus_tag="PC465_000352"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein E"
                     /protein_id="HDF2647688.1"
                     /translation="MQRSVAVVKNKTVKPNVIKLISGYIDFTTAAFAVMGFLLSRSII
                     VDSVAPLGIAFFICASKIDKYKIPVFISTLLGILLSSNDFGNVAKYAVCLTIFMAMNK
                     KLKLSDSIAKVAFIGAIILLPISMGQAFFSNRYVYGLLIAGVEAIIMFISIYVFSYGI
                     GLMANVNNRMSVRTEEAISISLLLTFSIMGIGDISLFGISIRTILSTVLILLTSIVGG
                     ATMGASSGVIIGVASILNNMTSAVYMGIYSFSGLISGAFNKINKYFCILGYILSWTII
                     YLYTSGITSNMMQLRDILLGCLIVLVLPERLFNKIEKLIKSNVASNEIVYDYIMRSKN
                     LTNSRLNSIYKTYDDLADTFDKIREKDKVLDQRDIANVIDMIHNDECKSCSMRRMCWE
                     SRFNHTYTMIYNILEKIEEKGELSLNDIPKNFRKECMKPESIVKISNHYYKMFVLDYD
                     WSVKFSESRKLIANQIRSISKSIKSLSQDLEGDIMLDIEKEKNIYEQLERYDITVDKV
                     SYLTKSNSEFEISIEKKTCHDGCMCEDKIVNIISDLVGENMSVRKIGCHCLGGKCKAT
                     FVKSQKYKAVTEVSAMSRDGHILCGDNYTYMEINDGKYMMAISDGMGKGKKAYEESSA
                     TIDILEKMIDAKIKDEIVIDTINNMLLLKSSEEMFSTLDLGILDLKRGCLETIKMGAC
                     STYIKREDGEVDLISSSSLPVGILSDVKIDRKNVKVKEGDYVIMVSDGIVDAGRNNNL
                     GDNWLIYFLKNIETTNPKEISNLILDRALELQALQIEDDMTVLVTKICTK"
     gene            65146..67038
                     /gene="pepF"
                     /locus_tag="PC465_000353"
     CDS             65146..67038
                     /gene="pepF"
                     /locus_tag="PC465_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HDF2647689.1"
                     /translation="MNRKLCKAIIPLFISIFCMLIISIKADQGYQKNNDRAITVMNNN
                     DTEDDAEKKQEIDYEKTCWNLQSLFKSDDQWKKELKSFDKDTKELKNYIGKVTKSPTH
                     LSFALNIKEKLDIRLNKLSAYVKLKQDTNKNSYKYLDMNDSMSKSYGNYMGICSDLEL
                     EILKLSNKDYKKIISNKNINRKYGAYLRDIRRNKVHYLDDKSEDILSKVSSISSLPSQ
                     VYELFRNMDRKTNLTPAQYASELESSDRENRKKAYQDELITYNDNINTIAGLITGQVK
                     KNIFYSQERGYESSLEMYLESDNVDEKVYNNLIRTVNSNMDSLHKYIDLRKKVLKLDK
                     VHSYDMFVPMVKAVDNNINYEKAQSIVYSALSPLGKEYNDVVYKAFNEKWIDVYSHEN
                     KVSGGYCLSVYENHPYILLNYNNSLGSVSTLSHELGHAVYEYLSSKNQNYFNSNPSIF
                     THEVASTTNEALLYEMLIKEAKGNDEKAYYITQYLDLIKDTLYTQTMYAEFEKTIHEL
                     VEKGKSVNALVLNDVWGQLLKKYYGQSYELDQLSKVGWARIPHFYNSFYVYKYATGCS
                     AGVSFAQDILKNGSDNYMSFLKKGSSDYPINLLKSSGINLTNTKPIENTIKKFDSLVA
                     ELEKLL"
     gene            67152..68117
                     /gene="galU"
                     /locus_tag="PC465_000354"
     CDS             67152..68117
                     /gene="galU"
                     /locus_tag="PC465_000354"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDF2647690.1"
                     /translation="MQVKVKKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIE
                     EAVASGIEEILIITGRNKKSIEDHFDKSVELELDLEKKGKKELLEVVQNISNMINIHY
                     IRQKEPKGLGDAIYCARHFIGDEPFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGV
                     QKVNQEDTNKYGIIEAKNIEGRVYKVKDMVEKPESGKAPSNIAILGRYIITPEIFDIL
                     KDLPPGKGGEVQLTDALKILSKKEAMYAYNFEGKRYDVGDKLGFLEATVDFALKKEDL
                     KEDFIKYLKHVCSEFDKNNNVLYNNTDEKIDLIEVNESRELEIQK"
     gene            68617..70221
                     /gene="rho"
                     /locus_tag="PC465_000355"
     CDS             68617..70221
                     /gene="rho"
                     /locus_tag="PC465_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HDF2647691.1"
                     /translation="MRRIFLILDDKVLEGLGSKTLVELREIAKELKIKSITTYKKNEL
                     IEIINSKSKNEEKVNEETKEKNEDIKEDIKNRKENIERESIEKEVEYKSPTKSYNKKE
                     IDTQNISQNQEHRNQRNDYNKTTSVNDSNKSSNISNRMVRNNNKNYYMPKQVDESKIV
                     DEFNTSKEDEVVGVLEILPDGFGFLRGSNYLSTEGDVYVSPSQIRRFNMKTGDKIKGI
                     TRHPKSGEKFRALLYVQKINDENPDTAIQRNAFETLTPIFPEERLTLETNRNEIATRI
                     IDLISPIGKGQRGLIVAPPKAGKTVLLKSVANSIAKNHPNVELIVLLIDERPEEVTDM
                     KESIEGDVIYSTFDQVSSHHVKVAEMVLNRAQRLVEHGKDVVILLDSITRLARAYNLT
                     ISPTGRTLSGGIDPGALHGPKKFFGAARNIRQGGSLTILGTALVETGSRMDDVIFEEF
                     KGTGNMELHLDRKLAEKRIFPAIDIYKSGTRRDDLLLDDEEKTALWRLRREMSNNSVM
                     EITDKVIELIKRTKDNKEFVKSIKNL"
     gene            70374..70574
                     /gene="rpmE"
                     /locus_tag="PC465_000356"
     CDS             70374..70574
                     /gene="rpmE"
                     /locus_tag="PC465_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HDF2647692.1"
                     /translation="MQKEIQPKYNPVEVRCACGNTFVAGSTKDEIKVEICSECHPFYT
                     GKQKNIEKGGRIDKFKKRFKMD"
     gene            70719..71612
                     /locus_tag="PC465_000357"
     CDS             70719..71612
                     /locus_tag="PC465_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1385 domain-containing protein"
                     /protein_id="HDF2647693.1"
                     /translation="MAKQAVGGQAVIEGVMMQSKDKRVVAVRKSDGEIALKEDRIKSW
                     VRDKNIDKIPFVRGSFVMIDTMIQGIKSLNFSSEFFMEEAEEDKFDLFIKKIFKDKAN
                     DIIIIFSLVIAMLLSAGLFIFIPTLVGGAFSKVMPNDFMLNLIEGIIRIAILFAYIVL
                     ISRSKDIERVFQYHGAEHKSIYCYENDLELTVENARKFKRLHPRCGTNFLFIVMAVSI
                     ILFAFFGWPNPILRIFMRIICVPIVAGLSYEVIRVLGKYDNGFTKIIAYPGMMLQYFT
                     TKEPDDEQLEVALEALKAVVD"
     gene            71630..72478
                     /gene="prmC"
                     /locus_tag="PC465_000358"
     CDS             71630..72478
                     /gene="prmC"
                     /locus_tag="PC465_000358"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HDF2647694.1"
                     /translation="MTIKDIIIKYSDKLKDISDTPRLDTELLLQKTLGVDRLYIHLNL
                     NKELTEEQKTKFMGFAEERLNGRPIAYIVENREFMGLDFFVKEGVLIPRPDTETLVEE
                     IIEICREKKDVSILDIGTGSGAITISLAKYIENSKIMSFDISETALEIAKKNAIINEV
                     GEKIKYINSDLFTAISDSNIKFDIIVSNPPYIKKQDIETLHKQVKDYEPYNALEGGED
                     GLDFYRRITEQGKKYLNKCGILAYEVGHNQAEDVINIMKSNGYKKIYTKKDIQGIDRV
                     VIGYNI"
     gene            72522..73586
                     /gene="prfA"
                     /locus_tag="PC465_000359"
     CDS             72522..73586
                     /gene="prfA"
                     /locus_tag="PC465_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HDF2647695.1"
                     /translation="MLKKLEVLEDTYKDLSEKIGDPDVINDQKVWQKYIKEHADLEPI
                     VMKYREYKSVLDSIKESKEILQEESDEELRELAKMELAEMEEKVAPLEEEIKILLLPK
                     DPNDDKNVIVEIRGGAGGDEAALFAGDLFRMYSRYAERRRWKIELLSASDTGVGGYKE
                     VSFMIKGKGAYSRLKYESGVHRVQRIPSTESGGRIHTSTSTVAVLPEVEDVEVEINPN
                     DLRIDVFRSSGNGGQSVNTTDSAVRVTHIPTGEVVSCQDGKSQLKNKEQALKILKARL
                     YDKALAEQHKDIAAERKSQVGTGDRSERIRTYNFPQGRISDHRINLTLYKLDAFLDGD
                     IDEMIDALITVDQTEKMTAI"
     gene            73715..74395
                     /locus_tag="PC465_000360"
     CDS             73715..74395
                     /locus_tag="PC465_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HDF2647696.1"
                     /translation="MILKVTIIGLLAGVIGTGLGGVISAIFKREVDKYLSFFMGLSGG
                     IMLAVVVFDLMKESMDKMGIINTVIFTFVGALITMYIKTKLDVSGNMASGYLIFISIL
                     LHNLPEGLAIGSSFMSTESLGITLAIVIGLHNIPEGLAMALGLVCNKMKLSKVILFTV
                     IAGLPMGLGSFLGVYFGGVFTSLIGVFLATAGGTMMYVVLEEIFPHSKSVYCIIGFLL
                     GTMIVNYI"
     gene            74424..75464
                     /locus_tag="PC465_000361"
     CDS             74424..75464
                     /locus_tag="PC465_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HDF2647697.1"
                     /translation="MKTIISNIDINNIDYEEIKIQAKLLREGKTVIFPTETVYGLGAN
                     ALDENAVKKIYEAKGRPSDNPLIVHIYEKEEVYDLAKDISDKAKLVIEKLWPGPITII
                     LNKKDIIPYKTSGGLDTVAIRMPSNVIARAIIKEAGIPIAAPSANISGRPSPTKAKHV
                     YEEMNGRVDGIVLGGDSNFGLESTVLDLTEETPMILRPGSITKEVLEELLGEVKLDPS
                     LSKKEDNQKAKAPGMKYKHYSPNADVYIISGKRENVATKINDMIKSNRDKGLKTGVMC
                     ISRNREFYDGEVIDLGNSLEEVASNLFDALIEMDKKGVDVIYSEEFPKTGVGQAIMNR
                     LLKSAGYKVIKA"
     gene            75481..75930
                     /locus_tag="PC465_000362"
     CDS             75481..75930
                     /locus_tag="PC465_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HDF2647698.1"
                     /translation="MNILIVCTGNTCRSPMAEAILRKAIKESGRSIEEYSISSAGIST
                     ANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESDIILTMTKSHKEILVQAVPKC
                     KEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVKKI"
     gene            75947..76399
                     /gene="rpiB"
                     /locus_tag="PC465_000363"
     CDS             75947..76399
                     /gene="rpiB"
                     /locus_tag="PC465_000363"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HDF2647699.1"
                     /translation="MKIGLGCDHGGYNLKKEIISYLESKGIECVDYGTNNATDSVDYP
                     VYGEIVANSVINKEVDYGILCCGTGIGISLAANKVPGIRCAVVSDVFSAKMSKAHNDA
                     NMLSLGERVLGKGLALEIVEAWINTDFEGDRHARRVNMIKSIEEKHNK"
     gene            76435..77056
                     /gene="upp"
                     /locus_tag="PC465_000364"
                     /pseudo
     CDS             76435..77056
                     /gene="upp"
                     /locus_tag="PC465_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011098621.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
     gene            77357..78172
                     /locus_tag="PC465_000365"
     CDS             77357..78172
                     /locus_tag="PC465_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HDF2647700.1"
                     /translation="MKNCIVVRGAGDLATAVIHKLHNSGFKVVALEIEEPLAIRRQIS
                     FCEAVYEKKVTVEGVECIFCNTEKEIEEVLSQHKVALIIDPKGEKLSKLNPIVLVDGI
                     LAKKNLGTTKDMAPFTIALGPGFCAGEDVDVVIETMRGHNLGRIITNGRAEKNTGVPG
                     AIKGFSKERVMHSQYDGIMENVCKIGDIVEKGDLLCYINNYEKKHEVRATISGVLRGL
                     LKDGAKVNKNLKILDIDPRKEEVKNAFTISDKARCIAGGVLEAILNNGIYPQN"
     gene            78398..78835
                     /locus_tag="PC465_000366"
     CDS             78398..78835
                     /locus_tag="PC465_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HDF2647701.1"
                     /translation="MRPSWDEYFMEIAEVVKKRSTCIRRQVGAVIVRDKQILTTGYNG
                     SPRNLEHCENIGCKRQELNIPSGERHELCRALHAEQNAIIQAAHNGISVDGATLYVTT
                     RPCVLCAKMCINAGILKIVYEGDYPDDMSTELLKEAGIELIKF"
     gene            79020..79247
                     /locus_tag="PC465_000367"
     CDS             79020..79247
                     /locus_tag="PC465_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AtpZ/AtpI family protein"
                     /protein_id="HDF2647702.1"
                     /translation="MSKRNTHTEIAKLFSLISQIGLMIVISILGCTFLGKFLDSKLNT
                     TPVLTIIFLLLGVGGAFSGVYKTLIVYTRRK"
     gene            79252..79638
                     /locus_tag="PC465_000368"
     CDS             79252..79638
                     /locus_tag="PC465_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HDF2647703.1"
                     /translation="MDIKLLNQVRSVTKGIVIFDVVLIVLMLITSTLSKPVLLGLIFG
                     SIIAMLNFRLLAISLEKSVTFPAGKAQAYASAQYAVRLFIMAVVLIASATVPHLNIIG
                     TALGLLSTKFVILSKNFINKLKRKEA"
     gene            79641..80345
                     /gene="atpB"
                     /locus_tag="PC465_000369"
     CDS             79641..80345
                     /gene="atpB"
                     /locus_tag="PC465_000369"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HDF2647704.1"
                     /translation="MNQAHYYLIGNFKISETILVSWGIMAFLAIASYFLTRNLKKVPT
                     SKVQIFLEFAVGGLAKMVTDVMGKNTVKRMPYMIPYIGSLFLFFACSNLSPLLGLRSP
                     TTDLDTTAAWAMITFFMIYFAGVKFKGLSYFKELAQPLAIMLPINIIGELARPISLSF
                     RPFGNILGGTIIMGLFYQLLGFISSLIPGLSIPIGEILIPVPLHLYFDLFAGLLQAYI
                     FIMLTMVFISSAGELD"
     gene            80414..80674
                     /gene="atpE"
                     /locus_tag="PC465_000370"
     CDS             80414..80674
                     /gene="atpE"
                     /locus_tag="PC465_000370"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HDF2647705.1"
                     /translation="METAIVAAASAIGAGIAVATGIGAGIGQGIAAAKAAEAVGNQPE
                     AKGDITSTLLLGVAIAESSAIYGLVISIILLFVNPFFKYLGM"
     gene            80797..81294
                     /gene="atpF"
                     /locus_tag="PC465_000371"
     CDS             80797..81294
                     /gene="atpF"
                     /locus_tag="PC465_000371"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HDF2647706.1"
                     /translation="MEKALVGITWEFVFQIVNTFIIFLLLRKLLFKPVLNIIESREND
                     IKSDLAEGEKAKNEGLALKKEYESKINFAKDEGQEIIKQATIRAEQKSDDIVNTAKKD
                     ALDIKEKANKDIEQERQKVINEIKNDISNIALLAASKVIEKDLDKSKHEELIENFIKE
                     VGEAK"
     gene            81291..81836
                     /locus_tag="PC465_000372"
     CDS             81291..81836
                     /locus_tag="PC465_000372"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HDF2647707.1"
                     /translation="MINVIANRYAEALFQLGEEENSTDVLFKELEKVVDMMTKVSKDF
                     YKVLKSPLVSKSEKKNLVEIIFSKEVSSNIKNFLKVLVDKDRISYLEDIELAYKELLN
                     KKNNVIDGVAISAIPMSETDIKELEVKLSNKYNKNVTIENVVDKTILGGVLVRIGNEQ
                     IDGTVKTRLDKMKEKLSEVIS"
     gene            81853..83355
                     /locus_tag="PC465_000373"
     CDS             81853..83355
                     /locus_tag="PC465_000373"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003405060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HDF2647708.1"
                     /translation="MNLKPEEISSIIKQQIKNYENKVELTDTGSVLTVGDGIASVYGL
                     EKAMSGELLEFPGEIYGMALNLEEEVVGAVILGDDSEIKEGDIVKRTGRIVEVPVGEA
                     LIGRVVNSLGQPIDGKGPIAYTKTRPVESEAPGIIDRRSVYEPLQTGIKSIDSMIPIG
                     RGQRELIIGDRQTGKTSIVIDTILNQKGKDVICIYVAIGQKRSTIAQLVSSLEKGGAL
                     DYTIVVSATASESAPLQYIAPYAGAAMGEEFMYNGKHVLIVYDDLSKQAVAYREMSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNV
                     ISITDGQIYLQPELFYSGVRPAVDPGISVSRVGGSAQIKAMKKVAGTLKLAYSQYREL
                     AAFSQFGSDLDEDTKKRLAQGERIVEILKQGEHQPIKVENQVMIIYAVINNHLEDIPI
                     DNIARFESELYAFVDNNYPEISRKILGGEDFTHDLTDAINEFKEKFVVEV"
     gene            83383..84261
                     /gene="atpG"
                     /locus_tag="PC465_000374"
     CDS             83383..84261
                     /gene="atpG"
                     /locus_tag="PC465_000374"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HDF2647709.1"
                     /translation="MAGAGIKAIKTRMGTVESTKQITKAMELVASSKLRKAKEKAEDS
                     REYFNTLYNTVKDIAQTTRGIRNEFLKEREVKNKCYVVVAGDRGLAGGYNSNVLKESV
                     SHMKGKKETVITVGKKAHEFFSKRNYNIAKDINSVEACGYEDATEISQTIIDLYKKGE
                     VDEVYIAYTKFKSALSQEVEILKLLPLVFEKDTDEQGMAVKEEKQNRSKVQYIPSAEA
                     VLSYIVPQFISGTVYGGILESFASEQGARRTAMESATDNANEMLSNLELSYNRARQSA
                     VTQEITEIVGGVEALK"
     gene            84274..85668
                     /gene="atpD"
                     /locus_tag="PC465_000375"
     CDS             84274..85668
                     /gene="atpD"
                     /locus_tag="PC465_000375"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HDF2647710.1"
                     /translation="MANVGKVVQIVGAVLDVKFDSEQSLPNLLNALVIKLGDKEIVAE
                     VAQHIGDDTVRCIAMSATDGLVRGMEVVDTGGPISVPVGDETLGRIFNVLGKPVDGKP
                     APKSAPKLPIHRPAPAYDELETTAEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTV
                     LIQELINNIAKQHGGISVFSGVGERTREGNDLYGEMSESGVINKTALVFGQMNEPPGA
                     RMRVALTGLTMAEHFRDEQGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLA
                     TEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPATTFSHLDAKTVLSRQISSLGI
                     YPAVDPLESTSRILDPSIVGKEHYEVARGVQSILQRYKELQDIIAILGMDELSDEDKL
                     IVARARKIQRFLSQSFTVAEQFTGNPGQYVPVKETVRGFKEILEGKHDDLPESAFLFV
                     GTIEDAVRKAKGSM"
     gene            85671..85931
                     /gene="atpC"
                     /locus_tag="PC465_000376"
     CDS             85671..85931
                     /gene="atpC"
                     /locus_tag="PC465_000376"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit epsilon"
                     /protein_id="HDF2647711.1"
                     /translation="MASEFSLKVVTPSNTFYDGDVEMIVVRTTKGDKGVLKGHIPFVS
                     GIPVGTLKIKKEGSFKEAKIAEGFINVTQDKTVILTESAEWI"
     gene            86394..86774
                     /locus_tag="PC465_000377"
     CDS             86394..86774
                     /locus_tag="PC465_000377"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HDF2647712.1"
                     /translation="MNIFDIGVDIIEIDRIRKAVDKNNRFLEKIFTDREIEYFNSKNF
                     KAESIAGNFAAKEAISKSIGTGIRVFNFKDIEVLRNEMGKPIVKTYNNLAKMCIDYNV
                     LEIKVSISHSKDYAIANAITIIKD"
     gene            86789..87250
                     /locus_tag="PC465_000378"
     CDS             86789..87250
                     /locus_tag="PC465_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDF2647713.1"
                     /translation="MMDKTAKEIMTTDVIVAKQDDSIADVANMLIAEKIGGLPVVDSE
                     NRVVGIISETDILKKEKYIEAPLYINLLQGLIFLDDLKKVEKDIKQVAAYKVGELMSK
                     DIIKVHEDDKFDDVANVMIKKSINRVPVVDDDNKLKGIICRYDIIKALYNE"
     gene            87271..87861
                     /locus_tag="PC465_000379"
     CDS             87271..87861
                     /locus_tag="PC465_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647714.1"
                     /translation="MRKKWTIVCIMFLALVIIVIGCQKRQSTKEEVYKDFQKQISDMN
                     YYSCKAEVEVVGNKSPHNYVLIHTYKKTDNYKLEVISPKHLKGKSIEYQGDKILVKNP
                     KISDVVELPNTGKNNQYLFVGDFIKNYLQNEEMKVKLSKGHLVLETFIPGDNKYFNKQ
                     VLYINADTKNPEKMEVLDKEGVPRFTVKYKDFEYRN"
     gene            87876..89033
                     /gene="alr"
                     /locus_tag="PC465_000380"
     CDS             87876..89033
                     /gene="alr"
                     /locus_tag="PC465_000380"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDF2647715.1"
                     /translation="MQKITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYG
                     HGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKIT
                     MTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEESVQEIIELNKLEYID
                     LEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLR
                     LNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTG
                     KETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEV
                     ILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLLK"
     gene            89066..89353
                     /locus_tag="PC465_000381"
     CDS             89066..89353
                     /locus_tag="PC465_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HDF2647716.1"
                     /translation="MYDKSKEKIEVTLPDSLISEVDSIVQMENSNREDFAKAAFQFYI
                     TQKKKIHIKESMKTGYREMGQINLSLAELGMTVEEVSSDDKNEGKIAQGEY"
     gene            89322..89705
                     /locus_tag="PC465_000382"
     CDS             89322..89705
                     /locus_tag="PC465_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDF2647717.1"
                     /translation="MKGRLPKVSTNCEIKRGDLYYADLSPVVGSEQGGVRPVLIIQND
                     VGNKYSPTVIVSAITSQINKAKLPTHVEISSNEYGLNKDSVILLEQIRTIDKKRLREK
                     IGCLDENMMIKVDDGLQISLGLFTF"
     gene            89876..90703
                     /locus_tag="PC465_000383"
     CDS             89876..90703
                     /locus_tag="PC465_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDF2647718.1"
                     /translation="MRDHKGLNEIARIIRRDIVSMIHRAKSGHPGGSLSVVEILTALY
                     FDEMNVDSSNPKMEDRDRFVLSKGHAAPALYATLAEKGYFDKEELNGLRKIGRMLQGH
                     PDMKGTPGVEISTGSLGQGFSVACGMAMASKLDNAPWNVYTLLGDGEVQEGIVWEAAM
                     SAAHYKLDNLIAFLDNNGLQIDGDIESVMSLGSIVDKFKAFGWNVIEIDGHDFDQIFA
                     ALDIAKSTVKKPTMIVAKTIKGKGISFMENQAGWHGTAPSDEELEKALLELGGADNE"
     gene            90696..91637
                     /locus_tag="PC465_000384"
     CDS             90696..91637
                     /locus_tag="PC465_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HDF2647719.1"
                     /translation="MSKMATREAYGKALVKLGQINDNVVVLDADLSKSTKTHDFYKSF
                     PDRFFNMGIAEQNLIGAACGLSTAGKIPFASTFAMFATGRAFEIIRNSVCYPKLNVKI
                     CATHAGLTVGEDGASHESVEDIAIMRAIPNMTVLVPADGVETEKIIFEIAKYNGPVYV
                     RLGRSSVPVLFDEDYKFEIGKGTVLREGKDVSIIACGIMVNEALLAQEKLQEEGISAR
                     VINMSSIKPIDKDLILESAKETNAIVTVEEHSIIGGLGSAVSEVVGESCPTIVKKVGI
                     KDTFGESGTPNELLKKYELTCDDIVKTVKEAIIAKRM"
     gene            92060..93154
                     /locus_tag="PC465_000385"
     CDS             92060..93154
                     /locus_tag="PC465_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647720.1"
                     /translation="MSEKVNVKTVISFAGAYVATVIGSGFATGQEIMQFFSFYGFAGI
                     IGGIISMVLFSWMGASVMSKGKELQLKEPIKIYRVYCGKYLGIFFEWFGPLFLFGVFV
                     VMISGAGATLTEYYGLNPFVGRVGMAVVALLTVSLGLDKLSKILGGIGPIIIIFTLLV
                     GGISLAKNIGNIGEAAQVLSTVKIAKPVPNAYLSGVIYTTYNTIVVMAFLTGLGASAA
                     NKKEAICGGILGGVALMAAAIMMHLAILSDIGNLYSKAIPSLFLADKISPVIGVLFSI
                     ILILGIYTTAVPLLWSVTNRFVDDKHPKFKLITLIAAILGLIGGFLPFDKLVGILYPY
                     TGYMGVIILVCVLYRQITKTSGYQEGISDK"
     gene            93380..93796
                     /locus_tag="PC465_000386"
     CDS             93380..93796
                     /locus_tag="PC465_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647721.1"
                     /translation="MNVKFNIKGIIYGVIALVFVIGGFIFIPSMFVEKSKPIDYTVLQ
                     RNSIPEKILDVMDKYTNEERALAAKIDNKIYIIVTRGNNKYGIEMDKIESVVEEGKDV
                     LRVKIKYKDKEDSFPYIVVETNMSELPDRIELNATK"
     gene            complement(93978..94547)
                     /locus_tag="PC465_000387"
     CDS             complement(93978..94547)
                     /locus_tag="PC465_000387"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HDF2647722.1"
                     /translation="MKKEFRKKVIESRKNKSANFVLSNSNLITEKLLQMEDIRNATNI
                     MLYLNFNNEVQTDNLIKKLLSLKKIVSSPITIKENHTLIPTQITDLKEGLRIGAYGIR
                     EPNEKSPTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
                     QIFDSIPKETHDAQLDYIVTETRIITPNS"
     gene            94701..95858
                     /locus_tag="PC465_000388"
     CDS             94701..95858
                     /locus_tag="PC465_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HDF2647723.1"
                     /translation="MYLVISKKKAIFLGVILVIITAMVTSAFQLTLGNKVVISKELYE
                     DYKKYDKLLGLESIIKQDFYKKVSDTDLVNGASKGLFLGTNDKYSGYYTKDEMENLIN
                     DSEGSYVGVGMYIGASKDGGLVVVPMKDSPAEKAGVKSGDKLVKVNGKSVSYKNSDEA
                     VRMMKGKKGKIVELTILREDKQLNFKVKTDQIIEKSIESKVIDNDLGYIEITQFISST
                     YTDFDKALKELKAKNIKGLVIDLRNNPGGMLDICKEVADELIGEGTIVYTKDNKGNTE
                     YLKSDKEKLGLPIVVLTNGESASAAEILTAAIVDNKEGISVGTTTFGKGLVQSVVRLK
                     DGTGYKLTTAQYFTPNGDYINEKGIKPTIEEKDENKQLDVATKWLREQIDK"
     gene            96023..96378
                     /locus_tag="PC465_000389"
                     /pseudo
     CDS             96023..96378
                     /locus_tag="PC465_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(96760..97512)
                     /locus_tag="PC465_000390"
     CDS             complement(96760..97512)
                     /locus_tag="PC465_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HDF2647724.1"
                     /translation="MEKKSPIIKNIVDSFRIIDVINEKGSIGIAKISEILSIPKTSVF
                     RIVKTLEEIHVIKQLENSDYTLDYRLLSYAKGTSQENKLISVAEPYLQKISKETGESV
                     NLGIRYQNEVIIVKSIEGEFYQLQTTLIPVSPLYCSGMGKLFLSQESEEFLQDYFNNL
                     EKRTVNTITEYNEFLLAKKRILELNLSIDNEEYEYGLSCYAVPIFDCNNDLICAISIT
                     GPSNRLMHKGEEYLIKVLKEQANNLQTEFSKL"
     gene            97762..98679
                     /locus_tag="PC465_000391"
     CDS             97762..98679
                     /locus_tag="PC465_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HDF2647725.1"
                     /translation="MKVSIIGAGAVGATTAFTLAKTSFVDEIAIVDIDQNRAKGNALD
                     ILHGLSLMHETRIVSGDYDCAINSDVIVITVGVPEKVGESRLVPLQKNVKILQDIIPK
                     ITSTSPNGLLLVVSNPVDIISYFSQKISGWEAKRVIGLGTTLDSARLNYLIARDLKIS
                     QTDIQGLVIGEHGDSQVVAWSQTSVKGTPFLDYVKSNNISLQEDYCNNLAQEVKDTAF
                     DVWDMKGPNCYCVALAIERVIKAIARNEHAILPVSQPADSEMYISQPHIIGRDGVQRR
                     VILSYDTQELNAFDTSYQSLQDIVKQIEI"
     gene            98698..99378
                     /locus_tag="PC465_000392"
     CDS             98698..99378
                     /locus_tag="PC465_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition domain-containing
                     protein"
                     /protein_id="HDF2647726.1"
                     /translation="MNISQTKGFFKFLILTLLGIVFLLIPFRFENGMDTILFHYLKLF
                     ISENHAVIQTIVVLLVCLSATLSLIDQLLPNTILRKQRLLKKLFSTTPFYVFNRIMGV
                     IIAMLCYLQIGPKFIISIDTGGAMLDLGTQLSVLVPLMLLFQTLILEFGAMEFLGQLI
                     GFIAKPLFKLSEICAVNIISAWVGPGNAAIIGTKELFEKGYFTVKESAVIGSQFSISS
                     IGWVVLVC"
     gene            99391..100029
                     /locus_tag="PC465_000393"
     CDS             99391..100029
                     /locus_tag="PC465_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition domain-containing
                     protein"
                     /protein_id="HDF2647727.1"
                     /translation="MDHFALIFLGITLIGIILAFINVRIPPISNYPDTYVDGSTTSKI
                     VSSTQGTRLQRAIIQSSMRANQVTLKNFTSKIDNMSFYVLWLTPIIIFWGALALIVSL
                     YTPLLTWVSYPIELVLKLANISEPAITASAIMSGFADNYLPVILGKGLESIESKTIIT
                     MMSILQLIFMSEIATLLQSCKVVKSFKDIIIIFLQRTIIALPFVIIFTKLIL"
     gene            complement(100617..101771)
                     /gene="nagA"
                     /locus_tag="PC465_000394"
     CDS             complement(100617..101771)
                     /gene="nagA"
                     /locus_tag="PC465_000394"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDF2647728.1"
                     /translation="MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNVTDNVI
                     DFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDT
                     LSDSVENISNSFNRVEGAKIQGIYLEGPFFTEKYKGAQNEKYFKNPDINILKLWQKKS
                     KNLIRKIAIAPERKGSIELTRYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYN
                     GMSPLNHREPGMVGAAMVLKDTYAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMR
                     AGAMEDGKYTLGKFNVNVKNSVARLNSGSLAGSVLTMDKAVRNIVDWNIATLEDAIKM
                     ATYIPALSCNIDNVCGSIHQGMEADFIVTDKDFNIYETYISGICMYKVNK"
     gene            complement(101854..102579)
                     /locus_tag="PC465_000395"
     CDS             complement(101854..102579)
                     /locus_tag="PC465_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2647729.1"
                     /translation="MIKRNDKRPIYDQLVEILRTKIENEMEPNDRMLSERKICDEYGV
                     SRTTVRLAMAELEHMGYIYKRHGKGTFVAALSQNSQNLMESYSFTDYMRTQGKKPGTK
                     VLSFEVVESTKYFSEKLGITPGEKMIKIMRLRLADDLPMMLERTYLPMKEFIGLTKEK
                     IEQKPLYEIFREDYGEIIKVADEEFSAGIISDKEAKLLEVPGDSPCLKLLRTTYNDDN
                     IVIEFTLSVARSDKFVYRVRHVR"
     gene            102846..103775
                     /gene="pfkB"
                     /locus_tag="PC465_000396"
     CDS             102846..103775
                     /gene="pfkB"
                     /locus_tag="PC465_000396"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDF2647730.1"
                     /translation="MITVITFNPSIDRMYRVNNINIGEVQRVVSKNATAGGKGLNVAK
                     VCKILKENPLAMGFLGGFNGEFIKNELRKLDIQNKFTKIEQETRNCLNIIEDNKVSTE
                     FLEKGPIVEKSDLERFENDIEEVLKNTKILVASGSYCENMPIDYYEKIGNICRANNIK
                     FILDTSGEALKIALKSKPYLIKPNIDEIRHLLGMNIESREEIILSGKKLIEMGAENVC
                     ISLGKDGMVYLNEDNVYDVKVPVVKCINTVGSGDSTVAGFSVGILRGYKIENLLKFAN
                     ACGISNALNMETGFVDLVEIDKYQDLVEVKKLS"
     gene            complement(103904..104821)
                     /locus_tag="PC465_000397"
     CDS             complement(103904..104821)
                     /locus_tag="PC465_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDF2647731.1"
                     /translation="MKNIKMGMIGLGSIAQKAYLPILTKSERFEFVGAFTPNKVKREK
                     VCSDYRIMPFDSIESLAKKCDCIFLHSSTETHYEIIKILLNLGVHVYVDKPLASTVSQ
                     GEELIELSTKKNLNLMVGFNRRFCPMYKEIKNNATEIVSINICKHGLNSLRNVKFDST
                     LIDDYIHVIDTALWLANEDVEISGEDLFLTDNKNLIFVSHKLKGKNFSINTSMHRDSG
                     TKLEQVEILSKGNIQRVKNLNVLEIEEGGNLTLKQSGAWVNILKQKGFEDISNHFIDC
                     IENNIKPAINGEECIKAQRLLEKIINSVK"
     gene            105292..106461
                     /locus_tag="PC465_000398"
     CDS             105292..106461
                     /locus_tag="PC465_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2647732.1"
                     /translation="MKMFKLEEQKLKDLGAIITTNEIKQQPELWLETYEIYKSNKEKL
                     SRFIDTISNNHGQFRVIFTGAGTSAYIGNSILPYLKNKNDIRKYIFEAIPTTDIVSNP
                     YDYLKKDIPTLLISFARSGNSPESLAALNLGNKIVDNFYHLAITCNPEGELAKMTKND
                     ENNYLLLMPSKSNDEGFAMTGSFSCMMLSAMLIFDSLEDDVEKSYINAIIEMGRNVID
                     RKDEIHELINKDFDRVVYLGSGGLGGLTQEAQLKLLELTAGKISTVYDSPMGFRHGPK
                     SFIDENTLVFEFVSNCLYTRKYDLDVLEEIKRDKIAKFTCAVSVENENNFSGTKFEFK
                     EKYNKLPDVYLAMPYILFAQTIALFVSVKVGNKPDTPSATGTVNRVVKGVTIYEY"
     gene            106510..107361
                     /locus_tag="PC465_000399"
     CDS             106510..107361
                     /locus_tag="PC465_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HDF2647733.1"
                     /translation="MALVTTTSMLKKAQDEGYAVGAFNVENMEMVIAVIEAAEELNSP
                     VILQTTPSTVKYAGLDYYLANAKVAAERVNIPVAMHLDHGSSFDLAMKALRSGYTSIM
                     IDGSHESFENNISISKSVVKACSPSLIPVEAELGKVGGKEDDLDGGNSNDYTNPKEAK
                     EFVDRTGISSLAIAIGTAHGLYKGEPKIDLDRLSEIKNVVSIPLVLHGGSGIHDDIIK
                     EAIKRGIAKVNYATELRIAYSKGVKKVLDEDSEVIDPKKYGLAGLQSVKDFVKEKIKV
                     CGSVNRV"
     gene            107687..109588
                     /locus_tag="PC465_000400"
     CDS             107687..109588
                     /locus_tag="PC465_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2647734.1"
                     /translation="MRERIILETLKNSSGYLNIDYFADKLGVSTRTIRNEIKKIETIK
                     ECNGFKLEYKSKLGYILNIKDQDKFEHYLRNLPSDLVENPEQRLESIIVELLVNEGYK
                     TIEQLSKKFLVSSSQIKNDLKKIDEKIKDTELKLERKAHYGIKIEGSIKEIQSILVDS
                     YFRGNRNITEYRNKFIDNLKLANIRSTIKNVLNEHDLEANLTELEEILAQIIILYIRV
                     SMRVVGNASDLKLYTEDLIIDKLLDKIFRDKKYNLNYDEKYYLKELIKLKTKDKKATI
                     KNIDKNKLQDIMFEFFREIDKKYNSNFLEDKEFFNLFYLHIACLIERIKKNHKIINPF
                     SVKISQQYPTVFNLSIQFSKIIENEYHIKISQDEIGFIATHIAVPFEKREEANFNKKY
                     KIAIICSSGGGSAFLINLRLKEIFPNAEIRNFSLLEEKAVIEFAPDLIFSITNLLFEI
                     NAPVILINEILDELDYLDIKESVRFADHIGNISSPKQYILGLFDKNHFRCIKDKAKYK
                     DILDSMSKCIVDEGACSPTYPKDVWERESYLSTIYTNGVAIPHPIEMTGNKNIISVAL
                     IQTDIIYENRVPKIIFMISLIKGNLELHKQISKYLSKIMANKDMVDMLNKSQSYEEFM
                     YKLKIYLGG"
     gene            109591..110634
                     /gene="ypdE"
                     /locus_tag="PC465_000401"
     CDS             109591..110634
                     /gene="ypdE"
                     /locus_tag="PC465_000401"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDF2647735.1"
                     /translation="MNIEFFKRLSEADGIASNEEEVRHVLLEELKAYSDKIICDGLGS
                     IIFSKIKDESAPNVMICAHMDEVGFMVRSIDKLGMIHLITIGGVKPLAQFVQKVRITT
                     KEGKKIPAVINATYNNGKAENIYADIGAYTEEDVYNLGINVGDMVTYTTSFEEFTLPD
                     RLVGKAFDDRIGCFVMGEVLKELRKENLNCNIHFAATSSEEVGIRGAKTSTQLINPDI
                     VFVIDVACAKNEFVRDYTNQKQIDKGVMLMHRDRTLVPSRKMIDYVMEIADKNNIPLQ
                     HDMFESGGTDGGEAHLVNEGKPCVVTCVPVRYGHCAFSIVSNKDLENIIRLYTQLILN
                     FDEEQYKHIRNFI"
     gene            110649..110954
                     /locus_tag="PC465_000402"
     CDS             110649..110954
                     /locus_tag="PC465_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2647736.1"
                     /translation="MSTEVQIMELISTAGESKSKAFEALKKVKSKDFKGAKLLIEEAR
                     KIDIEAHRIQTELITQDLNEDVESPAMSLLMVHAQDHYMTSQLAKDLIEALIYCLDK"
     gene            111051..111386
                     /locus_tag="PC465_000403"
     CDS             111051..111386
                     /locus_tag="PC465_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2647737.1"
                     /translation="MKILLCCAGGFSTNMLMQNMKKVVKESAKLNEKDFEFTAIPADS
                     IESEVDDWDIVLIGPQIAHKIDFLKGILEPKNKPFAVIDKDVYGKMDGATVMKLALIT
                     YKKHQLAQG"
     gene            111418..112740
                     /locus_tag="PC465_000404"
     CDS             111418..112740
                     /locus_tag="PC465_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2647738.1"
                     /translation="MFSKFEAFMNRVFMPLAHKVDNQRHLGSIKAGMVAMTPFTILGS
                     IFAILPALPNMLGENNPISKFILNNSAILDLPVSLSIGLIGLYACMCIAFNLGNYYKL
                     YIPGCVALSTFSFLFLVASFTPDGALEIGNLGAKGLFTGMIAGLGSVELYNFCNKKNI
                     TIKMPENVPDFVSRSFELIPTTIIVCGTFIVARFISLKVFGELPPQILTQFLSPLVGS
                     MDNPWSVLALNFAICTIFFFGIHSSVFSPITRPIMITFIAENIAAMQAGETIPHFFTA
                     GASSAFFGFTGCGISIGCVIACMLSKNASYKKIGRVSLFPALFGINEPILFGAPIILN
                     PIMFIPHVFGGAIIGTLPMFFMHWGWLAKPVFDPPYVGVFLEGFLTNGDWHSILANAL
                     QLVLAVLLYWPFFKIMERQQNNKKQKEETKNIFSKEEEDLLDDLGLDF"
     gene            112750..113820
                     /locus_tag="PC465_000405"
     CDS             112750..113820
                     /locus_tag="PC465_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2647739.1"
                     /translation="MNNTMERLVSLIYKRGVDALLIKAKNTKRYIGALSGSGVYVLVT
                     KDKNYQILDGRYIDEADKKTTGFIKRIVSQGSYIPTIIELLKELNIKKLAIENQAMSI
                     QEYLSLKNEGFEINLITNELWKLRAIKSKEEIELIKKACEITDEVFDEVISEIKKDMT
                     ELEVSALIQYHALKKGASGMSFETIVVSGERGAMPHGRPTNKKLKVNEAITIDFGVVY
                     QGYQSDMTRTISIGKPPKIIKEIYDVVLEAQLSAIESIKEGTRASDVDKVARKIIDKH
                     GFGEYFNHGLGHGIGLGDGEVPTLNPNSEDILVEGMVMSCEPGIYIPNVGGVRIEDDI
                     VIIDGKGVPLNKTSKEFIILGE"
     gene            113825..115012
                     /locus_tag="PC465_000406"
     CDS             113825..115012
                     /locus_tag="PC465_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2647740.1"
                     /translation="MKYNFNKVLNRKEGNCRKWSNHVIKEKFGLNEDAIPMDLADIDF
                     ECAPAIKESILKRASVGDYSYTFIGDDFYDAIINWNKRRFDVYIEKDWIKLTFGTVST
                     LHYIVQAYTKEGEGVLINTPAYDPFAEAVVNNNRKLCCSSLKLDNNRYYLDLEDMENQ
                     MKYENIRLLIFCSPQNPSGRIWTKEELYQVSELCLKYNVILVSDEIHRDIIFKDYRFV
                     SLWNAHPEIYKNSIICVSPNKGFNLGGLKTSYVLIRDVKIRETLLERLKSNSITSPNV
                     FAIPAIVAAYNESEEWLDAMTSYVEENFEIVYDFFETNIPKAKVMKSDSSFLAWIDVR
                     EVFRNEEESKEFFRHANLTMVVGSYFVKDGDGFIRINVGCPRETLNEALNRIKKTYIS
                     MYC"
     gene            complement(115209..116081)
                     /locus_tag="PC465_000407"
     CDS             complement(115209..116081)
                     /locus_tag="PC465_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HDF2647741.1"
                     /translation="MNILQNENLIIESSSFGAELTKIFSKKYDKNVLWDGNKKYWGRQ
                     SPILFPIVGKLFDNETIIEENLYSMTQHGFARDMDFEIVDKGDTFVTYKLTDNESTLK
                     KYPYSFELIINYTLNDNSIEVEWIVKNTDSKDIFFSIGGHPAFNLPFYEQNDFSKHYL
                     EFKSKNDVEKINLNGSFTDDIIPIGKLKNLQLNPEVFKNDALIYTNIDEVSICNNDGS
                     KYVTISMEDFPLVGIWTPYYSETNSTAPFLCIEPWYGLADSINSNKIYKDKKFINKLS
                     KGKVFTASYNINIH"
     gene            complement(116475..116666)
                     /locus_tag="PC465_000408"
     CDS             complement(116475..116666)
                     /locus_tag="PC465_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647742.1"
                     /translation="MDDFSKLKSLYEDGYRCIYHDCVDNNYTIYLKNFYTEGSETIEL
                     SSESDFSQFKDYIDGLRMS"
     gene            116886..117932
                     /gene="cobT"
                     /locus_tag="PC465_000409"
     CDS             116886..117932
                     /gene="cobT"
                     /locus_tag="PC465_000409"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HDF2647743.1"
                     /translation="MSLLESISKNIYSLDNSSIEKTKQRLDRLIHPTGSLGKIEDICM
                     QLAGIFGNENFDTSKKVIIAFAGDHGVYEEGVAPDPQNITKLQFPNFSKGLCGVGVIS
                     KFVGADVVAVDVGINCDEKLDGVLDYKIRKGTSNMAKGPAMSKQEAIRCLEIGIEIAE
                     QCIEKDYKVIGIGEMGIANTTPSTAIISVISGCDPLEVTGIGAGLKKERLKHKAEVIR
                     KAIEINNPNPTDGVDILSKVGGFEIGSMAGVILGCSANRIPVVIDGFISYAAALIAYK
                     INPKTREYMIASHLSAESGTKRALDILKLDPLLNMDMRLGEGSGAALAFDIIEASNYT
                     YKNMATFDEIDMGR"
     gene            117964..118524
                     /gene="cobU"
                     /locus_tag="PC465_000410"
     CDS             117964..118524
                     /gene="cobU"
                     /locus_tag="PC465_000410"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HDF2647744.1"
                     /translation="MSKIILVTGGARSGKSNFAEKLCFDRNNNTAYIATSIPFDDEMK
                     DRVKKHQENRPRNWNTYEIYEDIYSIIKEIYKEHETVILDCVTLLVNNLMFEHNLNIE
                     ESSQEEINKLEQYIKEQVVKLIEEIEKTNLYFVFVTNELGMGIVPGNKLSRIYADIVG
                     RINQYIASKSNEVYFVVSGIAMKIKE"
     gene            118534..119307
                     /gene="cobS"
                     /locus_tag="PC465_000411"
     CDS             118534..119307
                     /gene="cobS"
                     /locus_tag="PC465_000411"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HDF2647745.1"
                     /translation="MKRFILILQFLTRIPIKLNVGFDDEFYKSIVYFPLVGFVIGILS
                     YLIGWISMLLFEPFIASIIITLAGVLITGGLHIDGLGDTFDAIYSYRDKEKMLEIMKD
                     SRLGTNSLLAIMFVLLLKVGFVYDIISNNSLWVIIFMPMIARLGVMLLTYKTVTPREK
                     GMGNLFIGKLTTSMLITAIIYTLLIVALITKFIFLLPNIVLIKVLGSIIVVFVFIILF
                     KKHIYKKIDGVTGDILGCGIELSELVYLIYIYLLIFMFF"
     gene            119327..119941
                     /locus_tag="PC465_000412"
     CDS             119327..119941
                     /locus_tag="PC465_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDF2647746.1"
                     /translation="MIRLILIRHALTNDNKKGRLSGHINSCISEEGKLQINKITRYLS
                     NENIDKVYTTPSTRTKDTVEKISKLKLLEIEEKEALREISFGDFEGRTFEEIKIKYPN
                     EFEKMIKEGNNYRYPNGESLIDSYKRVAKEIDNIILENDSNLDTKTILICSHAGTIRN
                     IITHLISGSYKYHWNFKIDNASITVLEIDGGFAVIDKMNFTDFI"
     regulatory      120008..120187
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            120317..121816
                     /locus_tag="PC465_000413"
     CDS             120317..121816
                     /locus_tag="PC465_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HDF2647747.1"
                     /translation="MLQGTASNVGKSVLVAGLCRIFKQDGYTVAPFKSQNMALNSFIT
                     KEGLEMGRAQVFQAEAAKIEPIADMNPVLLKPSGNNKSQVIVRGKVVGEMPSSKYHDY
                     KLELVDVLKETFNSLNSRYDIVVMEGAGSNAEINLKDRDISNMGMAEIADAPVIIVGD
                     IDRGGVFASLAGTMLLLNEDEKRRVKGVIINKFRGKKELLQDGVKMLEDIIKVPVIGV
                     VPYTDIKIEDEDSVTTRFKKKMNKSDIHIEIIRTPHMSNFTDFNIFETQEDVSIRYVD
                     YGESLGNPDILIIPGTKSTIDDLTYIRKSGLESQIKNLHSQGKLIFGICGGYQMLGKK
                     LKDPYHVESEIEEVDGIGLLDTETTFEKEKTTTQVEATIVECISEYMNNLKGKKVKGY
                     EIHMGITKRGNDVRSLDLITKKLDKEVNYTEGSVNKEGNVIGTYLHGIFDEISFTRAI
                     LNNIRKKKGLGELESKVNSFNEFKDKEYDKLADFLREHLDIEKIYEIMK"
     gene            121855..123231
                     /locus_tag="PC465_000414"
     CDS             121855..123231
                     /locus_tag="PC465_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HDF2647748.1"
                     /translation="MKKILIAGTNSGVGKTTISLGIMQALVKRNMKVQPYKVGPDYID
                     PSYHTFITGRHSRNLDSYMLDDEKIKYIVNKSSKDADISVIEGVMGLYDGFGIDLDNC
                     TSSHTSKVLKSPVILVINGKSMAASSAAMVLGYKELDKDVNIKGVIVNNVKTNSHYQI
                     IKSSIEKYCNVEVLGYFPPNNKFSLESRHLGLVPSVEMKSLREKFYTLADEIEHYIDI
                     DRIIEISESDEFESDFDFQTLIENNKIKEHVNNKSIAIAYDKAFNFYYRENIELLEEL
                     GLEINYFSPLEDVSVPNADYIYIGGGFPEIFGKELEANESMRTSILEAHNNNIPIYAE
                     CGGLMYLGEKLLNQEEQEFNMVGIFSGISKMTSSLKRFGYCIGVAKENTLLSKKGESI
                     KGHEFHHSIFESDEKCVYSMRKERDGNIVEEWDGGYSKGNTLATYLHTHFYNNLNCIE
                     NFLKKGNE"
     gene            123232..124203
                     /locus_tag="PC465_000415"
     CDS             123232..124203
                     /locus_tag="PC465_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HDF2647749.1"
                     /translation="MSILSIYIGYVTDLIVGDPYSFPHPVRFIGKLINFTQGIIRKVS
                     KNDRQLKFGGFILWFITVGITYLTTYVIVKLFSFNILLSIVVNSFIIYTTLATKCLKD
                     EALKIYNVLKTEDIEKSRIQLSYIVGRDTTNLSEPEIIRATVETVAENTVDGIIAPMF
                     YAFIGGAPLAMAYKAINTLDSTVGYKNKKYKDIGFASAKIDDIANYIPARISVILMTI
                     GSFFLNYNYRNCFKISIRDRKNHKSPNCAFSEGAVSGALGIQLGGTNVYFGEKVYKPT
                     IGDKLREIDKEDIIKTNKIMYASSFVSMLVFTLIYVLCRMILINLII"
     gene            124235..125305
                     /locus_tag="PC465_000416"
     CDS             124235..125305
                     /locus_tag="PC465_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2647750.1"
                     /translation="MKDLGHGANVDEMARLYGKNPKEIIDFSSNINPNVLPNLERYIL
                     KGLEECRNYPDINYTNLRENISKYIDINPDFIIPGNGATEVIYLLMKSIKKKLAIINP
                     TFSEYRRSAELNNLDIIDLELDLENNFKLNIDIIKENIKRFDSLFICNPNNPSGNVQD
                     LKELVHLLDKHNKVLIIDETFMEFVEDESKYSLVKYIESNKNIFIIKAVTKFFGMPGL
                     RLGYGLTSNTEIMNKIYEHKEPWTINSFADILSNFIFEDKEYIKNSKEYYIEERKYML
                     QELRNIRNIKVYDTDANFILIRIYKKTTKELKKDLFKQGNILVRDASNFIGLDDSFIR
                     VAIKSHEDNKILIENMKNLLGD"
     gene            125307..126194
                     /locus_tag="PC465_000417"
     CDS             125307..126194
                     /locus_tag="PC465_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HDF2647751.1"
                     /translation="MKSYGICPASCGEFVQGIIDDEEYLCSYAIDMYSKVYIEEKLVD
                     INLGRYKSRLAIEKVFEKFNLPKKYTKNISLNINSKIPVGKGMASSTADIGATIKATL
                     SLIDKDLSSEEISKLAAEIEPTDSIFIDKNSIFNPLNGTVIKYLGNLTNAKVVILEPN
                     KVLDTMKIRLRQDYNKLKVENKEVIKKSFALLEEGLKKNNLSLVGEACTLSSLANENI
                     EKKECLNEIIKISKKYGAYGVNIAHSGTVVGILIDKSMNDKKMIDALCESNINSVYNK
                     IYTQNIINGGIKGEIEWNT"
     gene            126182..126814
                     /locus_tag="PC465_000418"
     CDS             126182..126814
                     /locus_tag="PC465_000418"
                     /EC_number="5.4.99.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003724727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-8 methylmutase"
                     /protein_id="HDF2647752.1"
                     /translation="MEYIKNPMKIEEKSFELIQEIIDEIRPDYKFKNNIEEKIIKRAI
                     HTTADFDYLDILKISEEAVDSIIDALKNNASIYTDTNMALSGINKRKLESLGCKYKCL
                     VADDETVKLAKEKGITRSMAAVEIAAKEEGRKIFVLGNAPTALYKVMEMKSEGRLDLD
                     AVIGVPVGFVGAQESKDEVEKTDIPYIISKGRKGGSNLAAAIVNAILYTM"
     gene            126823..128049
                     /locus_tag="PC465_000419"
     CDS             126823..128049
                     /locus_tag="PC465_000419"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase"
                     /protein_id="HDF2647753.1"
                     /translation="MEEYVYIDGKKYRRGYTTGSCATGASKAAVYMLITKNRINTINI
                     DTPKGIPLLLKVDNINISDTFVECSIKKDGGDDIDATHTMDIYARAEIVAKNDKNKGY
                     LTLKDIDSLSTNSECKSELYKFIRVYGGTGIGVVTKKGLSVDVGKPAINPTPLKMINH
                     EIRKLIGDNFESILGNDKVLKITIFAPQGETVAKKTFNPRLGIVGGISIIGTTGIVEP
                     MSDEGWKKSLSIELQMKKEQGLDKIILVPGNHGEQFIREKLNLDIKYVVRVSNFIGYM
                     IKEAQRIGYKKILMAGHIGKFIKVSAGIFNTHSKVADARSEILVANLALMGARYEFLN
                     KINQCVTTEEAVELINNSEYREVYNILSNKCRERVKQYLNEDSDDIDVEVIIFSMDKS
                     LLGKSDNTDDLVEVFI"
     gene            128046..128654
                     /locus_tag="PC465_000420"
     CDS             128046..128654
                     /locus_tag="PC465_000420"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HDF2647754.1"
                     /translation="MINIIGLGPGNLDYITKKGENLISTSDVLIGGKRNLESIKNFEG
                     EKIVLDSNLREIIEYINNNKEKQISIIASGDPLIYGIGRYLSKNIDNKMLNMVSGISS
                     LQYIFSKIYVDMNDVYITSSHGKVPDFDYILSHKKVCMVTDSKIGPKQISREIIDRNL
                     NKIIVVGENLSYDNEKITIAKPEEIIRIDNFDMNVVVILDEE"
     gene            128644..129219
                     /locus_tag="PC465_000421"
     CDS             128644..129219
                     /locus_tag="PC465_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HDF2647755.1"
                     /translation="MRNSEFITGKVPITKEEVRAISISKLNLVNAKNLIDIGAGTGSV
                     SVEAAYNYPNLKVISIEKNDDAIELIEKNKKKFNLKNIEVIKGYAPINLGLNVKVESI
                     FLGGTGNNLEEIIEWSKKNLVTGGRLVANFIIIDTFNQTLKLLKKHGFKEIDVCVLNV
                     SKLEKLGKGEYFKPLNPIYIISCEKGENDDE"
     gene            129212..129964
                     /locus_tag="PC465_000422"
     CDS             129212..129964
                     /locus_tag="PC465_000422"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HDF2647756.1"
                     /translation="MNKVHFVGAGPGDKELITLKGYKLLSNADVVIYAGSLVNPELLE
                     YCKEDCQIHNSAHMDLQEIIDVMREGIENNKSVVRLQTGDFSIYGSIREQVEDLNKLN
                     IDYDCTPGVSSFLGAASSLGVEYTVPEISQSVIITRMEGRTPVPEKESIQSYAKHQTS
                     MVIFLSVQEIEKVVSKLLEGGYPKDTPIAVIYKATWADEKIVKGTLSDIAVKVKENNI
                     NKTALIMVGRFLGEEYNNSKLYDKDFKHEYRG"
     gene            129948..131069
                     /gene="cbiG"
                     /locus_tag="PC465_000423"
     CDS             129948..131069
                     /gene="cbiG"
                     /locus_tag="PC465_000423"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HDF2647757.1"
                     /translation="MNIEGNIAIICITENGKKLALKINSLVNNCVIYQVKNKKSNLVV
                     EETCVHTVQKKLSDFVGEIFSKFDYIVFIMATGIVVRSIAPYIISKFSDPAILVMDEK
                     GKNVISLLSGHIGGANSLTQYISSLIDANPVITTATDINQKASLDMIAKKLNAHIDNF
                     RESVKEVNSMLVNNKCVGLYIDEGYQVDTRGFKLIESKDELRDSFSNTYIEKLVVVSN
                     KINCIEDIENLNLDNKFEHCYSTKKIIKVIPRDIVIGIGCRRNTDSELMYNSLEEFLN
                     KQNIDIRAINTVGSIELKKDEKAIIELSKILKVPFKTFSVDEISKVDNLFDKSDFVKK
                     NVGVYSVAEPVAYLLSKGNLLVEKHKYKGITFSVGRIKI"
     gene            131066..131791
                     /gene="cobJ"
                     /locus_tag="PC465_000424"
     CDS             131066..131791
                     /gene="cobJ"
                     /locus_tag="PC465_000424"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011701973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HDF2647758.1"
                     /translation="MIYVVGIGPGSKDTMTLEAIKAIEDSEAIVGYKTYIKLIEEFIQ
                     DKEIIQNGMRQEVDRCKQAVEEAKKGKKVAVVSSGDAGIYGMAGLILELISKEDEDIK
                     VKVIPGVTASIGAAAILGAPIMHDFCHISLSDLMTPWEVIEKRLRLAAEADFVICLYN
                     PRSKGRSEHLSKAFKIMGEFKSGDTPVGVVKDVGREKEEKLVCTFENMDFEKVDMTTM
                     VIIGNKSTYINGELMITPRGYTV"
     gene            131788..132540
                     /gene="cobK"
                     /locus_tag="PC465_000425"
     CDS             131788..132540
                     /gene="cobK"
                     /locus_tag="PC465_000425"
                     /EC_number="1.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A reductase"
                     /protein_id="HDF2647759.1"
                     /translation="MILILGGTSDSLSICDKINELKNQPYILSVTTDYGRELAQQHAE
                     NVILGKLGKEDMLKFIKDNNIVKIIDATHPYAVEVSKTAITCAKLLNIDYIRFERKSL
                     IEEIDYDNKFIVDTIEEACEIANKIGTNIFIGTGSKNLNRFIEEISDKNLVVRVLPTS
                     EVILSCEKLGLSADNIVAMKGPFSQYINEETYKHYNIDLVITKESGIAGGFLEKVNAC
                     KTFNIPVIIIKRESINYENVFNDINKIKDILV"
     gene            132559..134037
                     /locus_tag="PC465_000426"
     CDS             132559..134037
                     /locus_tag="PC465_000426"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HDF2647760.1"
                     /translation="MKKALLVVSFGTSYHETREKTIDICEDKIKNSLKSHDFFRAYTS
                     NMIINKIKKRDGIEIDNPIQALDKIYEQGYDEVIIQTLHIICGEEFNKLKEQVDGYSS
                     KFKKIVLGRPLLTHIEDYQEAVEAIKHQIPHMESNEAVVFMGHGTLHESHSAYPALEY
                     MLRDNGINAYVGTVEGYPEIEHVIRRLKEGNIKTVNLMPFMLVAGDHAINDMAGDEED
                     SWKTILEENGFNVRVHLKGLGENSYIQDKFVRHAVKCAENAKFYGIGAGPGDGSLLTI
                     KAVNTLKKLDILYTPESKKGGDSLALSIVSEYLPESVEIKSRHFPMSFDGNEKSLAWD
                     NVAQEIISDVNDGKNVGFVTLGDPMIYSTYVYIMKRILGEVEVETIPGISSFSNIASN
                     QNFPLVMDKEALVVIPCTMEDDKIEYALQNYNSIVLMKVYKNFKEIIKKLEKYDLIEH
                     AILVSNSSQESENVFTDLKEAHLEDKISYFSTILVNKDNKIK"
     gene            134067..134972
                     /gene="hemC"
                     /locus_tag="PC465_000427"
     CDS             134067..134972
                     /gene="hemC"
                     /locus_tag="PC465_000427"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HDF2647761.1"
                     /translation="MNIVVGTRGSNLALIQTEWVINELKKKYPEISFEIKIIKTKGDL
                     IQNVSLDKIGDKGLFVKEIEQQLLDGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPR
                     DVLILREGYKNLDDLPHGAVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDE
                     NMHGIVLAASGIIRANLQDKISSYLPVDVVIPAPAQGALAIEIRSNDSTIEGIVNSLK
                     DENTEIQILAERGFLDGVNGSCHIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDG
                     DISSPRELGLKLAKLVLKEYENYEG"
     gene            134962..136461
                     /gene="cobA"
                     /locus_tag="PC465_000428"
     CDS             134962..136461
                     /gene="cobA"
                     /locus_tag="PC465_000428"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HDF2647762.1"
                     /translation="MKGKVYLVGAGPGDYKLMTLKGLECIRKSDVIVYDRLANSSYLR
                     EAKPDCELIYVGKASSNHILPQEDINRIIAEKAKEGKIVTRLKGGDPYVFGRGGEEAE
                     TLVDEGIEFEVVPGITSAIGGLCYAGIPITHRDHASSFHVITGHLKGDDSGELNWNAL
                     ANNKGTLVFLMGISNLEKISENLMKEGKDKDTPVALISWATRYNQRVVTSTLENVYET
                     AIKEEVKPPTLIVVGSVVGLREKLNFFESKPLFGKSIAVTRSRNQNSVLVEKIMDLGG
                     NPIEIPTIKVEKIQNNINLENEIKNINKYNYLILTSKNAVEIFFEKIYEMNFDLRILS
                     NLKVCAIGSATSNELKKRGIIADIVPKKFVAESLYEELAPILNDDDNILIPRAENARD
                     YLVDKLKAICEVTEVHIYRTVIDEEKKGEILDILNSNDIDYITFTSSSTVNNLVEIIG
                     KENIKILEKIKTLSIGPITTETINSLGIKLYKESATSTIDSLVDLIIKN"
     gene            136478..137443
                     /gene="hemB"
                     /locus_tag="PC465_000429"
     CDS             136478..137443
                     /gene="hemB"
                     /locus_tag="PC465_000429"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HDF2647763.1"
                     /translation="MLRRPRRLRASKAIRNLVRETKVNVEDLIYPLFVVEGENIKEEI
                     KSLPDVYHLSIDMLEDEIKEISELGIEHIMLFGVPDEKDECASQAFNDNGIVQKAIRK
                     VKEINSDINVITDVCMCQYTSHGHCGILTDTGYVDNDKSLEYLAKISVSHAKAGADMV
                     APSDMMDGRIQAIREALDENGLENVGIMAYSVKYASNYYGPFREAAHSAPSFGDRKTY
                     QMDPANSNEAIIETELDILEGADILMVKPALSYLDIIRRVKDNFDLPLAAYNVSGEYS
                     MLKFAVKEGLLNEDVILESITSIKRAGADIIITYFAKDIAKLLKK"
     gene            137596..138174
                     /locus_tag="PC465_000430"
     CDS             137596..138174
                     /locus_tag="PC465_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="HDF2647764.1"
                     /translation="MLYPINLKLDELDVVIIGGGEVAYRKCKNFLEFNKNVTIVSKQI
                     LNKFYDLKGNIKIIKDDYKEIYIKDASVIIAATNNRELNMEIGLYCKAKNKLVNVVDN
                     IEISNFTVPSYIKRGDLLISVSTGGKSPSLSSKIKKEIEERYTEDYEEYLNVLGDIRK
                     KVIKKYEDKSKRKDVLNMLVTLDLEELKKFDI"
BASE COUNT        55127 a        14907 c        25059 g        43129 t
ORIGIN      
        1 ttttttattt tttgtcaaaa aaaacaaaaa atacgtattt cttttttcat ttcgggaaaa
       61 ctaaacacag gaattatgga ctttataaaa atttaattct tgaggagtga tataagtgaa
      121 aaaagttgct ttaattttag ctataatagg tgcgcttaac tggggtgcaa ttggtattct
      181 aggtacagac ttaataggta gtatctttgg tggaacatat gaaatggtaa gtagaataat
      241 atacttcatt gtaggtttag ctggattata cttaatacca agtttaatgt ctgatgatag
      301 agaataattt atgcttttat gttaaatacc tcattctaaa tgtttagaat gaggtattta
      361 attttataaa aatattaatt tgtttctttt ttaatggtaa aatagataag aattgaagtt
      421 ttaaaaagaa gtattatgta aaaaaggagt actattaata tatgtttatt attaatgaat
      481 taaataagat tgtaaatgaa gaagtaatat cttttcatat gcctggtcat aaaaagggac
      541 aggtttataa aaagttagga tataaagata tactaaaaaa tttgtataaa atggatacaa
      601 ctgagatatt aggaacagat aatttacact ttccggaagg aattataaaa aattcacaaa
      661 aaaaagcatc aagagtattt aaaagtgatt atacttgcta tttagtaaat ggtagtagct
      721 gtggaataca atctgcaata atgtcagtat gtagtcctaa aagtaaaata ataacaaata
      781 gagactgtca tcagtctgtt ataaatggat gtattttagg agatatagat atagagtatg
      841 tgccttgtga gataagtgaa gagacaaata tcttaaaagg gatatctata agtaatgtga
      901 ttgatataat agataaaaac ttggatgcaa aagcagtact gcttacttat cctacatatt
      961 atggaatgac atatgattta gaatacatat gtaattatgc acatagcaaa aagatggtag
     1021 tgatagtaga tgaagcacat ggtgcgcatt tagggcttag cgagaggctt cctaaaacag
     1081 ctcttgagca aggcgcagat atagttgtac agagtacaca taaaactctt ccagcattta
     1141 cacaatcgtc aatgatacat atacagggag accgagttga tatagataaa atattgaaca
     1201 tgttaagaat tacagaatct tcaagccctt catatttatt attatcttct ctggaattag
     1261 cagtagatat atatgaaaat aaaggaaaag aattaatgga agagctttta aataatatta
     1321 taactttcaa aaataaagtt gattcaaata ttaatatata cgacacaaat gataaaacaa
     1381 aaatatttat atcatctaaa aacatgggtt taacaggtta tgaactagaa aatattttga
     1441 gaaataaata taacatacaa gtggagttat ctaattatta tggagttctt ttaatatgta
     1501 caataggaaa tactgctgag gatttctcta gtttagaaac agcattaaac aatgttgtaa
     1561 aggaagactt taaatttgaa aagttagaaa ataaaaaata ccctgttgtt attccaaaga
     1621 aaatattaac acctagagaa gcattttata aaactaaaaa aagtgttaaa atatatgaca
     1681 gcataggtaa agtttgtggt gaatgtatag ttccataccc acctggaata agtgtaatat
     1741 ctcctggtga agtaataagt aaagaaataa tagactatct aatgttttgt cattctaaag
     1801 gcatgattgt gagtggattg aaagatgtag atttaaattt tatacaagta atagatttag
     1861 aagacattta aaaattatga tataaaagta gatagaagta gatagtttaa aattgtgaag
     1921 agaaataaat agactgctta tatagagcta tctaataaaa gtactaaaaa agtaaaaagt
     1981 gtttgtatgg aggatatgaa aatgaaaggt aagttaataa ttatagagag tggttcagat
     2041 gcaagtggaa aggctactca aacagaaata ttatatgaaa gattaaaaaa agaaggctat
     2101 atgattaaaa aggtagaata tccaaattat gaatctccat catctgcctt ggtgaaaatg
     2161 tacctaaaag gagactttgg taaaaatgca tcagatgtag acccatatat agcatcaact
     2221 ttttttacag ctgataggta tgcatcattt aaaaccgatt gggaggagtt ttacaatgaa
     2281 ggtggaataa ttatcgcaga tagatataca acctctaata tggtacatca ggcctctaaa
     2341 atggatattt gtgatagaga agagtattta aattggttag ctgattatga atttaattta
     2401 tttaagatac cacaacctga ttgtgttata tttttagatg tgcctattga atttagtaaa
     2461 aagcttatgg agaatagaaa aaataaaatt acaggggaag aaaaaaagga tattcatgaa
     2521 agtgacatag agtatttaga gaaatcttac aacaatgctt tatatatagc agataaatat
     2581 gattggaaaa aaataaattg tgttttagat aacaaattaa gaagtattga aagtatacat
     2641 aatgaaattt ataaaatagt tcttgattca ataaaaccta tggagagata aatatgtatt
     2701 ttgaaaatat tatagggcaa gattttgcaa agaaatattt aacaaattct ataaagaaaa
     2761 ataaacttaa taatgcgtat atgtttgaag gaatggatgg aataggaaaa aagaaatttg
     2821 cagatgaatt atcaaaacta ttacttgatt atgaaaatct cgaaaatagt ccagactatg
     2881 tactcataaa accagatgga aatagtataa aaatagctca aatcagaaat ttacaatcag
     2941 atatagtaat aagacctcat aaagactata aaatatatat aatcaataat gctgaaaaaa
     3001 tgactgtgga agctcaaaat gcacttttaa agacgttaga ggaacctcca aactatgcta
     3061 taataatctt agtcacaaac aacaaggaat ctttattaga aactataaaa tctagatgtg
     3121 atataataaa gttctcacct ataccaattg aagacttaaa acgttatttg ataaatacag
     3181 gtatagaaga agaaagagct caattattgg ctattttttc gagaggaagt attgagaatg
     3241 ctctaaatct atctcagtct tctgagtttt caatgatgag agaagatata caacagtata
     3301 ttcagataat gttagataaa aacatagtgg agattttaaa tataccaaat aatatggaaa
     3361 aatatagagg taagattata gctttattag atatgatgat aaactatttt cgagatatca
     3421 tcctattaaa agaaaatgta aacaagaaca tgttaataaa tgtagataag ctagttttca
     3481 ttcaaaatat gagtggaaaa attagttatt ctcaattgtc caagattatt gatataatag
     3541 aagatgcaaa gagtaaaata aaaagcaatt gcaatttcaa tataagcata caagttatgt
     3601 ctttaaatat atacgaggtg attaaatgat aaagatagta ggtataaggt ttaaaagtgc
     3661 tgggaaaata tattattttg accctgttga ttttaatata gagcaagata tggatgtagt
     3721 tgtagaaact gcaagaggct tggagtatgg gaaagtagtc gttggtccaa aagatatgga
     3781 tgaaagcgaa ttagtttctc ctttgaagcc aattataaga atagctacag aagaagataa
     3841 aaaagtatat ctagaaaata aggaaaaggc aaaagaaact tttgagttgt gccaacaaaa
     3901 aataaaagaa catgagttaa caatgttttt aatagattgt gagtatacat ttgataggaa
     3961 taagttgatt ttttacttta cagcagaagg aagaatagat tttagagaat tggtaaaaga
     4021 cttagctgct atatttaaaa ctagaataga acttagacaa ataggtgtca gagatgaagc
     4081 taaatctata ggaggtctag ggccttgtgg tagaaaactt tgttgttcat cttggttagg
     4141 tgattttcaa ccagtttcaa taaaaatggc aaaagaccaa agtctatctc taaatccaac
     4201 aaaaatatct ggaatatgtg ggagattatt ctgttgctta aaatatgagc atgatgtata
     4261 tagtgaagca atagaaaaaa tgcctgttgt aggtgcattg gtgcaatcag atgatggaaa
     4321 aggaaaagtt gtagaagtga atcctttatt agaacaaatt aaagtggaat ttcaagacaa
     4381 gacagtaaag atatatacaa gagaagatat aaaaatactt agagagccta aaaaatgtga
     4441 tggctgtggt ggtaaatgta aggataatga tggattagat gaagccacac taagagagct
     4501 aaagaaatta gaagattaaa tttaaggtag ggcttttcct acctttttta aagcaattaa
     4561 tgcttaaagt tattaatatt tgaggagaat ttatatatgc aattaaaaga ttcagaaaga
     4621 atagatgatt tacaattaaa aggccttaaa attatacaag atactaatgg tttttgtttt
     4681 ggtatagatg cagttttatt agccaatttt actaaaataa aaaaagatgc caaagtagta
     4741 gatttgggta ctggaactgg aattatacct attttgatag ctggaaaaag tgaagctaaa
     4801 aaaattattg gcgtggaaat acaagaagat gtatatgaaa tggcaactcg ttctataaaa
     4861 ttaaatggat tagaagaaag agttgagatt ataaatgaag atataaaata catagacaaa
     4921 gtcttagaca taaatggtta ccatgtagtc acatcaaatc ctccatatat gcatattgat
     4981 ggaataaaaa atccaaatga taaaaaagca atatcaagac atgaagtaag gtgcaatttg
     5041 gaagatgtaa ttagagctgc atccagattg gttatgccta gaggaaaatt cttcatgata
     5101 catagaccaa caagattggt tgatataata actttaggga gaaaatataa attagaacca
     5161 aaggttattc aatttgtgca tccaagacct caaaaagcac cgaacttagt tttggttcaa
     5221 tttgtaaaag atggaaggcc agagcttaaa atattggacc cattgtatgt ttatggagaa
     5281 gatgggaatt atacaaaaga attaaaagca atatataata ataaagatat aggagagttg
     5341 taaatgagcg ggaaattgta catatgtcca acaccaatag gaaacctaga agatataaca
     5401 tatagaactt taagaatatt aaaagaagta gacttgattg cagcagaaga tacaagacat
     5461 agtataaaac ttttaaatca ttttgaaatc tcaaaaccac taactagtta tcatgaacat
     5521 aataaggatt caaagggaga ttatttgata aataaactaa ttgatggtga aaatatagct
     5581 ctgataagtg atgcaggtat gcctggtata tctgacccag gagaagagat aataaaacaa
     5641 gctatacaaa ataacataga gatagaagta ttgccaggtg caacagcctt tgtaacggct
     5701 ttagttggct ctggtatgga cacacataga tttgtttttg agggcttttt agatagagat
     5761 aaaaaagtta ggaaagcaca attggaagaa ttaaaggaag aaagtagaac tataattttc
     5821 tatgaatcac cacatagatt gaaggataca ctaaaagata tgcttaaaat tcttggtaat
     5881 aggaatattt ctataaatag agaacttaca aaaaaatatc aagaaataat aagagaaaat
     5941 atagaaacta ccataaaaat atttgaggaa aaagaagtaa gaggagagtt tgtattaata
     6001 gtagagggtt ttcatggtga gaagtcaaag aaagaaaatt atgatgggct tacagatagg
     6061 gaatatgttt taaaactaat tgaaagtggt atgaacaaaa aagatgcaat aaaaatagtt
     6121 tgtaaagata gaaagttaaa gaaagatgtg gtttataaac aagttttaga tttataaagc
     6181 ctgaatctga ggtgatttta tggaaatagg gaaaattata atagagagtt taaagaggga
     6241 agatacacat aaaatattta tagaattaga taataagcat gaattagaaa aaataattcc
     6301 taaaataagc tgtatgaagt ctgtaggtga atgtaaatat catgtagtaa attgttttga
     6361 acattctata aatgcattaa aagaattaga aatagtatta aatgataagg atttttttcc
     6421 aatacatcta agaaaacatg tgtcaaacta tttaaacaca tatattgaag aaggaataaa
     6481 taagttacat gtattaaagc tgggaacatt tttacatgat ataggtaagc ctgacagtat
     6541 gaccttagat gaaaccggaa gagttcattt cacaaatcat gaaaaaatag gtgctcaaat
     6601 aattgacaat atgggaataa agttagagtt atcaacagag acatatagac ttataagtaa
     6661 atatgtaaga tatcatatga tacttttgtc tctatataag aaaaatgatt tgagtaggaa
     6721 agaattaatt aatgtattta acttagtaga tgaggacact ataggtgtaa taatgcttgg
     6781 gtatgcagat atagtgtcta cagtaaaatt attgggtaag agtggagaag tcagtgtgtt
     6841 aaagacatat atggaatata ttttaacaaa ttacttgtat aagagtaatt atacacatgt
     6901 ataaatttag ttaatataat tgagttttag atgattaatt aaagtttgaa atatacggat
     6961 ttcaaaaaca taaaagaagt tgtctttgtt gtaaaattat gaaagacaac tttttttata
     7021 tcaaaaattg aaattttatt aaggatactt aatggtctat taattaataa accattagta
     7081 tttaatttat attacaatat tgattttgct tgtattggcg ttgatagtat aacagaggtc
     7141 ttagtagaac caattttctt tatagtatca atcacatttt ctagctcgta catatctttt
     7201 acaattactt ttaaaagtaa gcaatcatca cctgttatat ggtgacattc tacaatccta
     7261 gggtcctttg cagctgactc aataaattct gtatatccat tgcttggaag agaaatatga
     7321 ataaatgcct ttataactct gcctaatgaa tctgggttga caatagcttt atatccttct
     7381 ataacaccag actcttctaa tcttttgact ctttctgaaa ctgcaggaga agttaaacca
     7441 actatttttc ctaagtcctt catagaaatt ctcccatcat cctgtaaaat ttctatgatt
     7501 ctgtaatctg taacatccat aaataaacag tcccccttaa ataaaaataa ttaatgctat
     7561 aaaacttttt tagaatctat catttgtgtt tttaaatacc aaagatttct agataaatca
     7621 accttataaa tgtgtggttt tgaaagtctt ttgtattgtt cccagatagt acttaattca
     7681 tattgtacat gattttttat ttcaagaaca gcttttttat tatatttgca tctgcctttt
     7741 atatacaatg gtttaagaag ctctttaact ttgtaatttg taaatacctt tgttttccat
     7801 gtataagtag gatggaagat ttctaaaggt ttagactcat ctataacttc atcatgtaac
     7861 ataatcaaat ctgcctctgc cttattgtct tcgttatata ttcttataac tttcttgtaa
     7921 ccaggattat ttattttttc tggattctca gaaatcttta tcttaggttc aagaactcct
     7981 ttttcacaag atgcagctaa tttataaact cctccaagag aaggtgaatc gaaagatgta
     8041 atgagctttg tacctactcc ccatgaattt atagtagctc cttctgcttt aagtgatgtt
     8101 atggtatatt cgtctaggtc attagatgca gtgatgctga tatctgaaaa gccagcgtta
     8161 tctaattgtt ttttagcttc tttagataaa taagctaaat ctccagagtc aagtcttata
     8221 cccataggtt tgtatccttt ttcagaaata tttttgaata cttttattgc attaggaact
     8281 ccactgttta atacatcata agtatctaca agtagtaggc atttatctgg ataaacatca
     8341 gcatatgctt ggaatgcttc aagttcatta tcaaattttt gtacccaact gtgagcttgt
     8401 gtaccaatta taggtatatc aaacattttc cctgctagta cgtttgcagt tccagcacaa
     8461 ccaccaacta cagcagccct agccccatat atccctgcat ctggaccttg tgcacgacgt
     8521 aatccaaatt caaatacagg gtctccttga gctgcaaagc aaactctaga ggctttagta
     8581 gcaataagag actgaaaatt aactattgtt aacaatgctg tttcaataag ttgagcttga
     8641 tataaaggtg ccttaacagt aattaatggc tcattaggga acatgatagt tccttcctca
     8701 acagcatata tatctcctgt gaatttaaat tcttttaaaa attttaagaa cttgtcagaa
     8761 aataaattta agttttttaa gtactctaaa tcttcatctg aaaaatgaag attatctatg
     8821 tattcaacaa cctgatcaat accacaaact atagtatacc ctccatcaca agcgtttttt
     8881 ctaaaaaaca tatcaaatac aacaatgtct tcatgaatat tcttttcaaa atagccattt
     8941 aacatagtaa gctgatataa atcagtaaga agtgttagat ttctcattat ttctctcctt
     9001 aattattatt aaatattaaa aattgtaaaa actcccacac ttatactaaa acataatata
     9061 gtacaacttt caagtataaa gtattaccta actatcataa aattatttaa agaggaggat
     9121 gattataata ggaaaaatat ggttttatat ggtatcgata ggaataatag gaagcttgat
     9181 ttctaaaaat atgggtgaat taaataaagt tatattaagt gaaacatcaa aaggtataga
     9241 gtttgcaata agtctagctg gtatcatggc actctggatg gggataatga atatcgcaaa
     9301 agaatcaggt ttaattgaaa agataggtca aaaactaaat cctataatga gaagattatt
     9361 tccttctatt ccaaaaggtc ataaagcaat gtcttatata gttatgaata ttgctttaaa
     9421 tatgttgggt gctggaaatg gtgcaacagc atttggttta aaagcaatga gtgagcttca
     9481 aactttgaat aacaagaaag atacagccac taatgatatg attatgttta tggtaatcaa
     9541 tatatcatct atacaaataa ttccatttac cataatcaaa ctaaggatgg atatgggggc
     9601 tcaaaatcca agtgaaataa tttttacgac tttatttgca accataatat ctacagcagt
     9661 agcaataata acatgtaaat tttttcaaag aagatataga taaaggggat gtagatacat
     9721 ggagatattt tcaaacttac ttataccaat aataattctg tacatagtaa tttatggtaa
     9781 atataaaaaa atagatgtgt atgatagttt tgtaaaagga gcaattgatg gattaaaagc
     9841 tgcatgggat atcctaccat atataatagg tatatttttg gcaataggaa tattcaaaac
     9901 tggtaaaggt cttgatatgt tagaatggct atttacacca atagcaaata tgatgagtat
     9961 accaaaagaa ttaataggtc taataagtgt aaaaccttta tctggaagtg gtgctttagg
    10021 gatgtacagt gaacttgcaa atagagttgg aataggaagt ttagtagaaa aaatgggtgc
    10081 tacgattgta ggttcttctg agactatttt ttacacaatg gcaatatact atggaagtct
    10141 gaagataaaa aatactagac atacattatc atgtgctatg attagccatg ttgcaggtgt
    10201 catagcagct gtttttattt gctatgtaat atttgtataa tttgttgaca atatgggaaa
    10261 aattttataa tatagtgatt atatagaaac aaatagtaat acaaattaca agctatgaaa
    10321 agaagagtaa ataaaggttt tttctatcag agaactaggt taggtgaaag ctagtgtcaa
    10381 aagctttatt gaagatggtc ttggagcttt ttatctgagc aagtgtgcta gggtaaaacg
    10441 gttggacacg ttatagtcta ctaaggtatc tataaaatgt ttctacattt catgtgaaac
    10501 ataactatta tagatgaatt agggtggtac cgtgaataat ctcgccccta tgttaactca
    10561 taggaggcga ttttttatta tttaaatgaa agaatcatat gattacgaac gataaaaaat
    10621 taggaggtaa ataacatgag caaaccgagt ttttatgtaa caacaccaat atactatcca
    10681 agtggaggat tacacatagg acatacttat tcaacagtag ctgcagatac aatagctaga
    10741 ttcaagcgtt tctgtggata tgatgtaaag ttcttaacag gaacagatga gcatggtgaa
    10801 aaaattcaaa agaaagccat agaacaagga atgtcagaga tagagtatct tgatggaatg
    10861 ataaaagata taaaggcctt atggaatact atggatatat cttatgatga ttttataaga
    10921 actacagaaa aaagacatac agacataata caaaagatat ttactaaact atatgagcaa
    10981 ggtgatatat ataaaggtga atatgaaggt agatactgta ctccttgtga gagtttctgg
    11041 acagaatctc aattactaga aggaaataaa tgccctgact gtggaagaga aacatattta
    11101 gtaaaagaag aatcttattt ctttagatta tctaaatatg aagacagatt aaaagagtta
    11161 tttaaagatg atagtttctg ttttcctgct gctagaaaaa atgaaatggt ggcaaacttt
    11221 ttagacaaag gattagaaga tttaagcgta actagaacga cttttgactg gggtataaaa
    11281 gttccttttg atgaaaaaca tgtaatttat gtgtgggtag atgctttatg taactatata
    11341 acagcattag gttatatgac tgataatgat gaagaattta aaaaatattg gcctgccaat
    11401 gttcaaatag taggtaaaga aatagtgaga ttccatacaa taatatggcc agcgctttta
    11461 atggctttag gtctagaagt tccaaaacaa gtatttggac atggatggat actatttgct
    11521 gatgataaaa tgagtaaatc aaagggtaat gtggtttatc cagaacctat aatagaaaga
    11581 tatggaatag acacacttaa gtacttctta ttaagagagt ttgcatttgg gcaagatgga
    11641 agttatactc atagaaattt tgtaacgaga ataaattatg atttagcaaa tgatttagga
    11701 aacttaataa gtagaactgt agctatggtt gaaaaataca ataatggtat aataccaaca
    11761 gcaaaagttt caactaattt tgatgctgac ttaaaagaac aagctgtttc aactagagaa
    11821 aactttgaag ctgaaatgga taaaatgcaa ttccatgaag cattagagag tgtatggaaa
    11881 ttagttagaa gaactaacaa atatatagat gaaactatgc cttgggcact agctaaagat
    11941 gaaacgaaga aagatgaatt agacacagtt ttatataatt tatgtgaatc tataagaata
    12001 atcgcaacac taataaatcc tataatgaat gagactgcta ataaaatata tgaacatata
    12061 ggaataaaag gtcaagatga tataactaca tgggaaagta caaaaacatt tggtcttatt
    12121 ggagaaaatg taaaagtatt taaaggtgaa cctttattcc caagattaga tgtagaaaaa
    12181 gagatagaag aattaactaa aatgttctct gggaaacctc cagtagaaga aaaaccttta
    12241 gagcataaag aagaaattac tattgatgat ttagacaaaa tagagcttag agtagggaaa
    12301 ataataagct gtgaaaaaca tccaaaagca aataaattat tagtatcaca agttaagatt
    12361 ggaccagaaa caagacaaat agtatcagga atagctgaat actataagcc agaggattta
    12421 gtaggaaaag aggttacagt ggtatgtaac ttaaaaccag ttaaattaag aggtgtagaa
    12481 tctcaaggta tgatattagc agcaggtgat gatggagacc catatgtttt accatttaca
    12541 caaggggcta aagatggatg cgaggttcgt tagtaggtaa ttaaatagta aggagattaa
    12601 agatgttatt tgactcacat gcacatttaa atgatgaaag ttttgatgaa gatagagatg
    12661 aacttattgg ttcattaaaa gataaaggtg tagatttggt tgtaaatcca ggagcagata
    12721 tagagacgtc gataacagca attgaacttt cgaaaaaata cgactttata tattcagcag
    12781 ttggggtaca tccacatgat gtatcaaaac tagatgatac agcaatagaa actctaagaa
    12841 aacttgcaac tgagaatgaa aaagttgtag ctattggaga gattggatta gattattatt
    12901 atgattattc tccaagagaa gaacaaaaag agtggtttaa gaagcaaatt gaattagcta
    12961 atgagctaaa acttccaata ataatacatg atagagatgc acatggagat acttttgaga
    13021 taataaagaa tactaaaaat cctgaaatag gatgtgtact tcattgttat agtgggaatg
    13081 tagagttagc tagagaatat gttaagatgg gttgttatat atcaattcca ggcacggtta
    13141 cttttaagaa taataaaaaa actagagaag tagtaagaga aatacctcta gaaagattat
    13201 tcatagagac tgattcacca tatatgtcac cagagccaca tagaggaaag agaaacaatc
    13261 cttcccaagt atcttttgtt gctgataaga tagcccagga aaaagggata tcttatgaag
    13321 aagtatgtag agttacaaaa gaaaatgcaa agaaattttt taatataaaa tagacaaatt
    13381 aaatcttata atgatatata taataagtca ttataagtat aggatgagag tgcctcaaaa
    13441 tgagtttttt agttcatgag gcactctttt ttttatgaaa tcaaatatat tttcatcatt
    13501 tcaacaatga aaaagaagtt tatcatattt tgagatagtt tgtttttatt tatttaattc
    13561 atattttaaa atatattttc ttaacattgt taaaaaagaa tttacaagat attcattaga
    13621 attaactcaa ctctaatatt cacttaactt aagttgttta ttatattatt aaagagaagt
    13681 aaacgaaagg tagattaagg aggttgaatt ttgtatacag ttgatagtac taagatattg
    13741 ataaatatga acttagagaa actagaaaag atatactcaa tgataaaaga tacatcaagt
    13801 atttctataa ttaaagaacc taacttggct acagtaatgg taagagctaa tgaaagtgta
    13861 aaaaacacaa catttaattt aggagagata ttagttactg aatgtagtgt aaaggtagat
    13921 gaaagcttgg gttacggaat agtttcagaa aacaataata agaaagccat ttatttagca
    13981 gttatagatg cagttttaca tagcaataac agtaaatttg atgagttaaa gaattacata
    14041 aataaaagtg tatatgaaga gaacttaagg tatgaacaag agattattga tgaatttagc
    14101 ttgattaata aaacgaaagt tcaattcaat gctatggatt aaataggagg agaatcatgg
    14161 taaattatac acaagaaata tatagaaaga tgctagatag tgcttcattt cctgggaaat
    14221 taaataatat agataatata aatatagaaa ataatacaaa actattgaat ggagcaattg
    14281 gtatagcaat cactttatta gaccaagaag ttaccttcta tatagaaaat tatactcaaa
    14341 aagatataaa aaatataaga gcacttacaa tgtcaaatca aatagattat agaaaatcag
    14401 attatatatt tttagatatt aattcagaag tggatatatt acagattaaa ataggttctt
    14461 ttgaatatcc tgatgaaagt gcaactatag tacatcaagt aaatgattta tcaacgtact
    14521 ctcaaactaa gtatataaag cttgatttga gtggtcctgg tataaaatct aaaaatagta
    14581 tatatataaa tggaattaga gaagaattta tagaaagatt atctagcata aataaagatt
    14641 atccaatagg aatagatttg attttagtag ataaaaaagg agaaattgca tttataccaa
    14701 ggtcatcaaa attaagttgg gaggtattat agaaatggct tatgtagcag ttaaaggtgg
    14761 agaagaagcc atattacagg ctaaaaatat acttgagttt tatagggtaa aaggagatag
    14821 cttgcctata gatgtaaagc agattgagga acaaatgtct tatgctgtag acaaagtaat
    14881 gtctgaagga agtttataca acaaggaact atcagcattg gctataaaac aagctcaagg
    14941 tgatatatta gaagcctctt tctatgtaag agctttaagg tcaacaatgc ctagaattac
    15001 atattcagaa cccataaata cagaagaaat gagaataaaa agaagaatat cagctacttt
    15061 taaagatata ccaggaggtc agtatcttgg ggcaactaga gattatgaaa atagaatatt
    15121 gaatgtagaa ttattagaag aagatgaaaa aaagaataga gattttagag atagttttat
    15181 aaatgaatta gaaacagtag atgaaatccc tgaatttaca aaaatatcta atatatttag
    15241 aaaagaaaat ttattacaag aagaagtttg tgaaaacaaa ttggaagaag ttattgatga
    15301 tattacaaga aatagtttaa gatttccagt ttctaggtca gcaaagttac aggcattaac
    15361 tagaggtgaa agtggagtag tgtcaggttt tgcttatgct attgtaagag gttttggtga
    15421 tgaacatcca tatataagtg aacttagaac tggtaatgta tttataaaag taaaacatcc
    15481 catctatgaa gatgaagaaa taataatagg ggatatgctg gttactgaat gtgaaatagt
    15541 ttcaaaagca tcacaaaata agactgaaaa ttctaaaact aattcggaag ataaaaataa
    15601 gatgtcttta ggatatggtc tttgtatggg gaataatgag aataaggcta tatctatggc
    15661 catactagac aaatctttgg agccaaatag tgaaaaacta gcacaagatg aagaatttgt
    15721 attgcttcat atagatggaa tagattcatt aggatttata tctcacttta agcttcctca
    15781 ctatgtagat tttaaagcgg atgtagaaag aataaaatag tttgtggagg taagtttagg
    15841 tgatatataa ctatggtttt ttagacgaaa acacaaaaaa agaaataaga agaaagatat
    15901 taaaagcaat atcaatacct ggttatcaag ttccctttgg ttcaagagag ttgcctatag
    15961 ctaagggatg gggtactgga ggtttacaat taacactatc attaattggt aaaaatgatg
    16021 tagtaaaagt aattgaccaa ggaagtgatg attctacaaa tgcttgtaat ataaggagct
    16081 ttattgcaag tgtaagtaat gtagaaacca caaaagatac attagaagct acattgattc
    16141 aaacgagaca tagaatacca gaagaaaaac ttaaatctaa tcaaatacta atatttcaag
    16201 taccaatacc agaaaccctt agaatagtag aacctagtga agtagaaaca agaagaatgc
    16261 attcagaaga agattatagt aggatgtggg tatatcttta tgaagatata gttagattta
    16321 atgatatatc tatagcagtt gaatatccat gtaaagtaaa tgatagatat ttaatgaatc
    16381 catcacctat acctagattt gatataaaaa aattaaatat gtcagacaat ttattcttgt
    16441 ttggtgcagg tagagaaaaa agaatttatg ctattcctcc atatacaaag gtagaacctt
    16501 tagagtttga ggattataag tttgaagagg aaaagtttga aggaaaatac tgtagtttat
    16561 gtaacagtac aaatacattt ttagatgaag tatatgacag tgacactaat gaaaagtact
    16621 atagttgctc agatacaagt tattgtgaaa aagttagatt aaaaaataac agtatagatg
    16681 tgacaatagg aggtacttgg aatgagtaaa ataaatgact ctaaaagatt agaaaatata
    16741 gacaagcaag tattaatagg aagaaatatc aatcttattt atggagatgg gtgtgaaaag
    16801 tgttttgaaa gcacaggata tgaaagcaat aatatatgta agtattgtgg ttctatagtt
    16861 gcatgtaata atgtaaattt agaactttat gaaggagaag tccttggaat tgtaggtgaa
    16921 tctggttcag gaaaaagcac tttattaaaa atactgtttt tccaagaaca tgcaaatagt
    16981 ggagaagtat atatattcca ttacaataaa gacacaaata tactagagct ttcagaccaa
    17041 aaaaagagat acataaagaa tcattttatg ggtattgtgt atcaaaatcc ccaccttggt
    17101 ttaaatttag actttagtag tggtggtaat atagcagaaa aattattgat ggcaaattta
    17161 tataatgttg aaaaaataag agatagaggc aaagaacttt taataaaaac taatatacct
    17221 gtagaaagaa tagaccataa accaaaatac tttagtgggg gaatgcaaca acgagttcaa
    17281 atagcaaaag ctctttcaaa taaccctcca atattgctat tagatgaggt tacaacaggt
    17341 ttagatgttt ctgtgcaagc ggaagtattg gatttaataa gagaaatcca aagagaactt
    17401 aagatttcta tgatagttgt atcccatgac tttgatgtta taaagatgct tgctgatagg
    17461 acaattgtaa tgaaaaatgg aagtgtgatt gagtctggtc ttacagacca aataatggag
    17521 gacccacaac acccatatac tcagcaactt ataaattcat tgctataaat atcgtttgta
    17581 aataagcaaa atgggggttt ttaataaaat gaaagaaact atacttgaag taaataattt
    17641 tagtaaagac tttgagttac atgcattgaa caagactata acggcatgta gtaatataag
    17701 ttttgaagtt tcaaaaggtg agtttttagg aataataggt aaatctggag caggtaagtc
    17761 taccatatta aaaagtatct ataaaacata tataccaaca actggagaaa taatttttaa
    17821 ttcagaaata tatggtaatg tagacctggc taaaattgga gaccgagaaa tgataaatct
    17881 tagaaagaaa gaaataggat atgtatcaca gtttttaaag acacttccac gaataactgc
    17941 aattgaactg gtagtacatt ctttaattga gagtgggttt gaaaaagatt gttcgtatga
    18001 tatggcaaaa gatatactta accaatttga aataaaggaa aatttatggg atgcgtatcc
    18061 aaataatttt tctggtggag aaaaattaag attaaattta gctcaagcta tggttaaaaa
    18121 gcctagactt ttgttacttg atgaaccaac tgcatcactt gataatcaat ctaaaatata
    18181 tgtaaaagaa aaaatgttgg agcttaaaag tcaaggaact acaatgatag gaatttttca
    18241 tgatatagag tttatggaaa ctgttataga taagaccttt actatggcaa aagggactat
    18301 aagtgaaagt ggggtagcct agatgataaa actaattcat aatgcaaata ttgtattaga
    18361 agatatgatt ttagaaaatg gtcatttaat catagaggga gatacaataa aaaaagtatc
    18421 aaatgataag attgattacg catttgactt taatgagata gatgaaataa tagatgcaaa
    18481 aaacttatat gtaatacctg gtattataga tattcacagt gatgccattg aaaaggaaat
    18541 agagccaaga ccaagtacat tattaccatt taatatggca ttttatgaac tagataaaaa
    18601 actaccttca aatggaataa ctacagttta tcattctata tctttagggg atggagtagg
    18661 agttagaagt attgataact ctttaaagat gattaaaaat attgattcat ataaaaatat
    18721 agatagtaag agcataaatc ataaagttca tttaagatat gaagtgttgt attatgaagg
    18781 tttagaaaag gttttagaac tattagatga aaataaaata gactacttat caataatgga
    18841 ccattctcca ggacaaggtc agtatacaaa tccaacattt tataaagagt atgctactaa
    18901 agtgtgggga gttacagaaa attatgtaga tacatggtta gatgatttag taaatctgca
    18961 tgataattta gattggaata aaatagctaa tattataggt atagccaaaa ctaaaaatat
    19021 aaatgttgca tcacatgatg atgatacatt agaaaaaatg gatttcataa aaaatatagg
    19081 cataaatgta tctgaatttc ctataactct tgaagttgca aaacattcaa agaaattggg
    19141 tgttctaact tgtttaggtg caccgaatat tgtaagaggt aaatctcata ataacaattt
    19201 aaaagcaatg gatgctatat tggaagattg ttgtgacatt gtgtgttcgg attatcttcc
    19261 atcagctatg ataaagtcta tgtgtatagt tgcagaaaga ataaataatt taaataaagc
    19321 agtcagttta tttacctcaa atcctgctaa agcagttggt atatatgatg aaagaggtag
    19381 tataaaagaa aataaaaaag cagatttagt tttagtagat attgatagtg aatatccaaa
    19441 ggttgtaaat actattgtaa atggaaaaac agtttataaa agggaggtat aaagattgct
    19501 aacagagtta cattgtcata caagtatatc agataataat tttactactg aagaaataat
    19561 aaaaaaagca gcagaaaaga atataaatat cttagcaata acaaatcatg acacattatc
    19621 tggattggat gaagctcttg tgcttggaga gcattatgga ataacaataa taccaggtat
    19681 agaaatttca gcatatgatt ataaaaatag aaaaagagtt catattcttg gatataacat
    19741 agatttaaac agtcaagaaa taaaaaattt gtgcaatcca atggtatgtg acagacataa
    19801 agcatctgtt aagatggtaa ataaaattat agatttagga tacaaaatat ctttggaaga
    19861 tgtaaagaaa tattcatcaa agactggaat atttaaacaa catataatga aagctcttat
    19921 agataaaggg tatacagata atatatattc aagtctatat aaagaattgt ttcatagagg
    19981 aaacggcaag gtatatgtat ctttaaaata tgtggattac agagatgcaa taaaagctat
    20041 aaaaaattct ggtggaattt gtgtgctagc tcacccaggt caaatggata attttagcgc
    20101 tattgaagag atggtaaaag taggattaga tggaatagaa gtatatcatc catctcacaa
    20161 caaagaacta gaaaaagagt cgctttctta tgctaagaag tataatctag tggtcacagg
    20221 aggctcagat taccacggat tttattctca acataattat gaacttggaa gcaagagctt
    20281 aaataaagaa gatttattta agtttaggtt agctttagga ggggtattat aaatgtcttt
    20341 tttacaagta aaaaatgtag gtaaaagtta tggacaagtt aaggtgttaa aagacatatc
    20401 tattgatatt gaaaaaggag agtttatttg tttactaggt ccaagtggtt gtggaaagag
    20461 tacactactt agaataattg cagggcttga ggataaacat ggtggaaaaa taataataaa
    20521 tgataaggat atgactaatt caccacctga aagtagaaat tttggtatag tttttcaatc
    20581 atatgcatta tttccaaata tgaatgttta caaaaacata gcctttggac tagaaaataa
    20641 aaacataagt aaatctaata ttgataaaaa agttaaagaa gttctagaag ttgtagaatt
    20701 aagtggatat gagaaaaaat atccatcaca attatcaggt ggacaacaac aaagggttgc
    20761 attagctcgt gcgattgctt tagagccaga ctttttactt cttgatgaac ctttatctgc
    20821 attagatgca aaagtaagac ttaaacttag ggagcagatt agaagtttac atagaaaact
    20881 aggcattaca actataatgg taacgcatga ccaagaagaa gctctttgtt tagctgataa
    20941 gatggttgtt atgaatagag gagaaataat acaagttgga acgccaaagg aggtatataa
    21001 aaatccagaa acaccttttg tagctgattt tataggaaca ataaatttta tagatgatgg
    21061 tattaataag atagctatta gaccagaaga tataaaagta gagtctaaca gagattctaa
    21121 agataaggat ataaaagtgg gagaaatttt agatatcgaa tttagaggat ttaactatag
    21181 aattacagtt gagtatcgtt ctaagcaaat gaaattagat gtagtttcca aagttgcaga
    21241 acaaatgaaa ctgtgcatag gttctaaaat aaactttaag atacctaaag aaggaattgt
    21301 acaatataaa tcagagggat gtgcttaata gctaggggtg aataaatgat aacatcaaaa
    21361 aataaaagaa gaataagtga tagcacaata caaaaatatt tcttgatttt ttcggtaatt
    21421 gtactaatag tatttatatt atttccatta gtatcattat taaaaaatgc atttatggat
    21481 acaagtggaa attttatagg aatttcaaat tttagtaaat atgttgaaaa tccaagtctt
    21541 atagcatcat ttaaaaattc aatttttgta tctacagtct catctttaat atcactatgt
    21601 ttagcattta tatattcata cgcaataaca agaacaaaca taaagtttaa agattttttt
    21661 aaaactatgg gaatgtttcc actttttgca ccaactatgt tatatggtat ttcacttata
    21721 tacctttttg gaaataaggg aatctttaca accatgggtc tggaagtacc actatatggt
    21781 ccattaggaa taattatttc tcaaattcta tttacatttc cacaagcttt tttaatatta
    21841 tctgtagcac tttcgatggc tgattacaga ctttatgaag cagcagatag cttgggtgct
    21901 agtgaattta agaaattttg caaaataaca attcctggta taaagtactc attacttagt
    21961 tcattctttg tatcctttat acttgcattt acagattttg gagcagctaa ggtagttgga
    22021 ggaaactaca atgtactggc cactgacata tataaacaag tagttggaca atttaacata
    22081 ccaatgggag ctactgtttc tatggtaatg ttaattcctg tactaatagc atttacatta
    22141 gataagatgg caagtaagaa acaaggtatg accataactg caaagtctat gccatataag
    22201 attaaggaaa ataagtttag agatagagta tttttaatag tatgtagttt tataacattg
    22261 ctaattttta ttttaatatt cgtttcagtt ataggttcag ttataaagtt atggccatat
    22321 aatttaagct ttacaatgga acactataca tttaaaggta ttttgggaag tggaataaaa
    22381 acatacttaa gcagtttgaa aatatcaact ttaacagcaa tatttggaac tatatttgta
    22441 ttttttagtg cttatatgat agaaaaggtg gataagtttc ctaaattaag acaaacagct
    22501 taccttttat caatgatacc aatggcctta cctggcttag ttttaggtat atcatatata
    22561 acttttttta actcagcaag taatccatta aattttttat atggaagtac agcaatatta
    22621 gttatagtaa atgtagttca tttttattca gtttgtttta taacctcaaa ttcatcttta
    22681 aaaatgttgg ataaagagta tgaattagtt gcaaaatcca taaatattcc attctataaa
    22741 gtatttttta atataacagt tccaatgtct ataacatcaa tacttgaaat agtagtatat
    22801 tattttgtaa attcaatggt tactgtttca gcattaatat ttttatatac acctcaaact
    22861 cagactgcat caatatcaat actaaagtta gatgagatag gatatatagg accatcagct
    22921 gctatggcag tattagtgct tttaacaaat ataatagtaa gacttttgta cgaatttgta
    22981 acaaagaaat taaaaaataa cacacaaaaa tggcagcaaa aagatgttgc ataggggagg
    23041 taaaaatgaa atttaagaag ctagtttctt taggagtatt atcaacactt ttattaagtg
    23101 taataacagg atgtagtact gattcatcag gttcagattc aaagtctgat agtaagacaa
    23161 aaggggattt aacagtttac acagcaattg aagaagatag tatagagcca tatttagcta
    23221 catttaaaga gaaatatcca gatattaaat taaatattgt tagggcatca acaggagata
    23281 taacagcaag attattagca gaaaaggata atcctcaagc agatgttgta tggggagttg
    23341 cagccacaag cttattggtt gcagatgacc aggggatgtt agaaccatat gctccaaaag
    23401 gttctgaaga aatagagtct gcatttaaag atgataaaga agttccttct tgggttggga
    23461 tagatgcttg gatgacaggt ataacagtaa acactaaaga attaagtgat aagaacatcc
    23521 cagttcctag ttcttacgaa gatttaataa agccagaata taaaggtctt atatctatgc
    23581 ctaatccatc ttcttctggt acagggtact taacagtatc agcccttata caaattatgg
    23641 gggaagaaaa agcatggcag tatatggata agttacatga gaatattggt gtatacactc
    23701 aatctggttc agctccagct acatcagcag cttcaggaga atatcctatt ggtatatctt
    23761 ttggatatag aggtataaag ttaaaagagg aaggctatcc agtagaagta gtatttccaa
    23821 aagaaggttc tggatgggat atagaagcaa atgctcttgt gaaaaaagat aatataaaag
    23881 aagcatcaaa agtattttta gattgggcta taagtaaaga tgcaatgaac gaatactcta
    23941 aaaactatgc agttactact atttctacag gaaatccaat accagaagga ttccctaaaa
    24001 agccattaga gcaaatgata gataatgatt taaaatcagc agcaaaaaat agagaagata
    24061 tactaaataa atggatatca aaatatgatg gtaagacaga aaaagagagt taagtaaaac
    24121 tatacaaatg gagtaaaaag aaaaattttt ttaagtagat tttattataa taatataagt
    24181 tgagaataat ataggtcaag aaaagtgaat attctataaa aatgtataga gtaagtatac
    24241 cattcagttt gaatggtata ttttttattt ttagagatta atttagaaat agatatacta
    24301 cagtttaaaa tagtatattt taatttcatt attaaagtat agatgttata tataaagtaa
    24361 ataagatatt aaataattat aaactaaagt aaataaaata ttgagcgatt attaaaaaga
    24421 tatatatata taatttaatt tgagcagttt gttatatatt ataaaaaaga gaaaaataaa
    24481 aggtaaattg tttctggata acttaaaatt ggaagtaaga atatttaact agagaagaat
    24541 tatttaagct caggttagct ctaggagtag ctgattttat aggagcaata gattttatgg
    24601 atgatgatat aaacatgata gcaattagac cagaagatat aagggtagaa tttaatagag
    24661 atttcaaaga aattatagac ctcaaactca gaccgtatcg atataaaaac taaagctaga
    24721 tgatatagtg ttgtatatag gaccatcagc tgttatggca gtattagtgc ttttaacaaa
    24781 tataatagta aaacttttgt atgaattgat aataaaaaaa ttaaaaacca agacataaaa
    24841 atggcaacaa aaagaagttg aataagggag gtaaaaatga aatttaagaa gttagtctct
    24901 ttgggaatat tatcaacact tttattgagt gtaataactg gatgtagtaa tgtttcatca
    24961 ggttcaaact taaagtctaa taataagaca aaaggagagt taacagttta tacagcaatt
    25021 gaggaagata gtatagatac atacttagct acatttaaag agaaatatcc agatattaaa
    25081 ttgaatgtac ttagattatc agtaggaggt ataacagcaa gattattagc agaaaaagat
    25141 aatcctaaag cagatgtgtt atggggtgtt gcagctacaa gtttgataat tttagatgac
    25201 aaagaaatgc tagagccata cgctccgaaa ggctttgata aggtaaatcc tgcatttaaa
    25261 gatgataaga aagttccttc ttgggttgga atagatgctt ggatgactgg tataacagta
    25321 aatactaaag aattaaaagc taaaaatata tcagctccta gttcttatga agatttaata
    25381 aagccagaat ataaagatct tatatctatg cctagtccag cttcttcagg aacaggatat
    25441 ttaacagtat cagaactcat acaaattatg ggtgaagaaa aagcatggca gtacatggat
    25501 aaattacata aaaatattgg tgtatacact cagtctggtt cagcgccagc tatattagca
    25561 gcttcaggag aatatcccat tggtatatct tttggaaata gaggtataaa gttaaaaggt
    25621 gaaggttatc cagtagaagt agtatttcca aaagaaggtt ctggatggga gatagaatca
    25681 aatgcacttg tgaaaaaaga taatataaaa gaagcagcaa aagtattttt agattgggct
    25741 ataagtaaag atgcaatgaa tgagtattct aagaattttg cagttactac aattgacacg
    25801 ggaaatccgg tgccagaagg atttccaaag aatccattag aacagatgat agataatgat
    25861 ttaaaatcag cagcaagaaa tagagaggct atactaaata aatggataga aaaatatgat
    25921 ggaaagacag aaaaagagag ctaagcctta caataaaatt tagtacaaaa agcgcctaga
    25981 atataagttt tatatctagg ctcttttgat atatttattt aaaatgcata tttctatata
    26041 aaaataaata gtttagtacc ttgattaaat taaataaaaa ccttaaaata aagagatgta
    26101 aagaaaaact aaaaacgaat aaaaggtgaa tttatatgat aaaagaaata atagtagtag
    26161 agggtagaga tgacgttaca gcagttaaga gagcaataga tgcagaactt ataactacag
    26221 gtggatttgg atttccaaaa ggtgtaatgg agcgtataaa agctgctaat gaaagacgtg
    26281 gtgttataat atttacagac ccagattttg caggtgaaaa aataagaaaa aaaatagcat
    26341 cagaagttcc aggatgtaaa catgcatttc taccgagaga ggaagctaaa aaggatggag
    26401 atataggtat tgagaatgct actcctcaaa gtataatagc agctctgaat aaagttagaa
    26461 ctgaaaatac agaaaaaaga tatgaattta agcaagttga cttaattaga aatggtctta
    26521 taggtaatga agaagcatca cttagaagag atgcacttgg aaaaatactt ggaattggat
    26581 atggaaatgc aaaacaattt ttaaatagat tgaataatta tggagttgaa agagaagaat
    26641 ttatagatgc attaaaacaa atctaaacgt aatgtttaat gtatgaaaaa tatgtatata
    26701 aaataaattg tggaattacg gttaatttaa gataaattat ttataatata taccttattt
    26761 taaatcaatg taaatacata taaataagta taattaataa aattaaatat caaaataagt
    26821 taaaaaggag taaataatgg atagactatc ttcacataat gcaacaaagg aagtagtaca
    26881 aaaatataat tttaaatttt caaagtcttt aggtcaaaat ttcttgatag atagtaatat
    26941 aattgataaa atcttatctg gagctagaat cacaagagga gataatatca tagaagtagg
    27001 acctggtata ggaactctta ctcgtgagat gggtaaaata gcagaaaaag tagtggctat
    27061 agaaatcgat agaaatctaa ttcctatatt gaaagatacc ttgtcagatt tagataatac
    27121 agaggttgta aatcaagata tactaaaagt agacatacag gaattagtaa aagataaatt
    27181 aaatggtggg ccagttaagc ttgtagcaaa tcttccatat tatataacta ctccaatagt
    27241 tatgaaattt ttagaggaag acatacctgt aacagacata gtagtcatgg ttcaaaaaga
    27301 agttgcagat agaatgaatg ctattccggg tactaaagat tatggggcat tatctatagc
    27361 tgttcaatac tattgtgata cagagattgt ggcaaaagct ccaagacata tgtttatacc
    27421 acaaccaaat gtagattcca cagttatagg tttacatgta agagataaaa gaaaatatga
    27481 tgttcataat gaagacatat tttttaaaac agtaaaagca tcctttggac aaagaagaaa
    27541 aactcttctt aattcgttgg gaggtcttgg ttttcttaat aaagatgaaa taagagaagt
    27601 attaaaagaa gctaatatag acgaaaaaag aaggggtgaa actcttagta tagaagagtt
    27661 ttcagttctt tcaaatataa taaatacaaa agtatcttct aaatagaagg tacttttttt
    27721 aattttgtta acatatattg tttagagaaa ctgtgttaag gggggattgc agtgggttct
    27781 aaaagaaagt ttaaaagaga ctatataata ctagaagcta aagacataaa ctttagatac
    27841 aaagaacgag tactgccaaa agcttttgca aaagttgaag taaatgatga aaaagcaatt
    27901 attgcattat atgtagaaaa tctaaaatat gttaaagatg ggtataaagc agtagcaata
    27961 aaagatgacc atggattaat agacttagga aatataattt taaatgaaca aggaagaggt
    28021 gaatttgttt tagatttaga agattatgat gatgagataa aaggtattgc attattgtat
    28081 gaaagaaata tacctttaat tggatttaaa ggaaataagc ttgaaaatta tgaggacata
    28141 ttatttcaag aggtagagga agaagaatat gaagaatatg aagagttgga agaagaagac
    28201 gaagagatag aggataatga ggaaagtgat agagacgaag gtagtgaaga agaatatatt
    28261 atagaagaat atgatgaaga tgagtatgaa gactattggg aagatgatga agatattgaa
    28321 gaaggagagt taaaagcaag aacggaagta gaagattcta gtgatgagga aatagaagag
    28381 ttcaataatt ataaggaaat agaaaattat aatagggtta aagtacagga agaatatata
    28441 gacatagaat atgatgaaga agaagaggaa gaagaagttt ttgaagtaaa tagagaagaa
    28501 gataggtttg tttcctcaaa acctactaaa tcaaagaaag ttcaaaaaga tcagaataat
    28561 attgaaaaaa taaaaagagc taatggagta agtcaaggag agagtggaaa taaacaaacc
    28621 agtacattac ttatgccaag acaaataaaa aaaggtttga aattatttaa agaagtaaaa
    28681 ccttttgtaa cagattatat agataagaca agatggtgga aaatagagat aaatcctaca
    28741 acactgtgtg gatatacaat gccttattta ggatatttaa acgtattgaa ttacactatg
    28801 tatagtgatg cagttttaca ttcatataaa tacagacact atttatttgg agttcagtat
    28861 gatgaatata ataagagaaa acattatatt tatgctatcc caggaaatag aaatgaacag
    28921 ccagacaatg gaagcacagg atttttaaga tatcaagctt gtgataatag aacaaatagt
    28981 ttaggatatt ggctatgttt tatagattct agacaaagaa atatagttag gtaaaaataa
    29041 taaaaatgaa aaaatttaga ctcaattctt attttactga aaaaattaat gaaatgtagt
    29101 acaaaaattt aaaaactatt gataatattt aaatattaca ctacaatata tcttgaaata
    29161 cctattatat tatggaggaa aattatgata aacgagcaaa gaattttaaa tgagtttctt
    29221 gaattagtac agatagatag tttatcttta aaagagggga atgttgctaa agtattagtt
    29281 aaaaaattag aagaaatagg ttgttcagta gtaatagaca atgctggtga aaaagcaaat
    29341 ggagaaactg gtaatataat agctacatta aaaggaaata aagaaggaaa gaaaatatta
    29401 tttagttcac atatggatac agtaactcca ggtatagggg taaaacctat agtggatgaa
    29461 gcaaatggaa taataaaaag tgatggtact acaatattag gttctgatga taaagcaggt
    29521 atagcagcta tattagaagg cttaagatat ataaatgaaa ataatataga acatactgat
    29581 atacaagttg tattctctat atgtgaggaa tgtggattag ttggagctaa aaatttagac
    29641 tatggaaaaa tagattctga atatgcattt atattagata gtggtggttc tccaggtgaa
    29701 ataatagtaa aagctcctgc acaagatgta ataaatgtta agatattagg aaagactgct
    29761 catgcaggtc ttgaacctga agctggaata agtgctataa tggtagctgc cagagcaata
    29821 gaaaatatga atttacttag aatagacgaa gaaacaactg ctaacatagg aattataaac
    29881 ggtggaacag ctacaaatat agtaacagga gaagttaata taattgcaga agccagaagt
    29941 ctaaaagaaa acaaattaga tgttcaaact aaacacatgg tagagacttt tgaaaaagct
    30001 gcaaaagatt ttggagctca aattgagata gatgtcaata gagcatacac accaatagat
    30061 gttagtgagg attctgaaat aataaaactt gcaaagaagg ctttttcaaa cttaggtata
    30121 gaaggtcata ctgaatctac aggaggaggt agtgatacaa atatattaag taagaatggt
    30181 atcgaagcta taactttagg aattggtatg aaaaatgctc atacactaag tgaacatata
    30241 gctataaaag acttatatga ttctgctaaa atggtagtgg agataataaa ggaagcataa
    30301 atttaaataa tagtgtataa tatatatatc gcctagctta agctaggtga tttttcattt
    30361 tatagaagat tgataatctc tattgaaagc aaagagtata catttgcata taagagagtg
    30421 tttaatttat gttcaaatgt aggttcttaa taatatttag attgtttcat aagggaggaa
    30481 taaatatgga aacaaggtat gaagaagcaa ataaaataac aatacaatca atactttgga
    30541 atatagtatt aacaataatt aaggttatag ctggtgttat tggtaattct agcgctatga
    30601 ttgcggatgg attacattca gcatcagata ttataagttc tataggagta ctaataggca
    30661 attatgtatc ttctagacct ggagatagag agcataatta tggtcatgag aaagcagaga
    30721 cattagtatc atttgtgtta tcaatattgc ttattttcgt ttctataaca ataggtatag
    30781 aggcaattaa atctttattt aacttagatg cattaagtgt tccatcaata ttaccattag
    30841 tagtatcagt tatttcaatc ctgataaaag agtatcaata tagaataaca ataaaagttg
    30901 ctaaaaagat aaattcacca gccctaaaag ctgatgcttg gcatcatagg tcagatgctt
    30961 tatcttcagt agctgctttt ataggtatag gtggttctat tttagggttt aaaccattag
    31021 acccaattgc gtcagttgta gtggctatat ttgtagctaa agtaggaatt agtatactta
    31081 taagttctgt taatgaattg atggatgttt cagttgatga agaagagata aaagaattaa
    31141 aatttattgt agcagataca gaaggtgtta aaaatcttgg tgatataaag actagaaaac
    31201 atggagctat ggcatatgta gatttgacta tatgtgtgga tgaaaatttg acagttaagc
    31261 aaggtcatga tattgctacc aagcttgaaa aacatataat aaaacatatg gaatttgtaa
    31321 aaggcataac agttcacgtt gaaccatgta ctaattgcca aggaaataag tgtaataatt
    31381 aattaaaact taaaaaaaag tataaaaagt tatataattg ttttatgatt ataaactcta
    31441 ggggtggtta aatgagcaag aaaagaaaac taaagaaaaa agctgcaata ttaataggag
    31501 tagttgtttt ctttataata tactttatat cctttagaat aggaataaac atggaaaagg
    31561 ataaaagtga agtgccaaag aaggtagaaa aagaagaaga agataatagg tctttaagga
    31621 ctcaaataaa agagaagaag aaggtttata tatcagataa aaatatagaa aacataaaaa
    31681 ttgaagaaga tatgtgggat gaaataaagt tatttttctc agattttaag aaagtaagaa
    31741 atactacttc ttcttacgaa gcagtttatg aaggttattc tgatgatgga gttaaatttt
    31801 ctactgacct taactttttt agagtatata ctgtaaataa agaagaatat tataaagtac
    31861 cagttagttc taaggatgct tttaagaaac ttttagatga gagtatatat acttcgtttg
    31921 accttttaag tcattataaa gattggaaag aggttactat aactcatgga aaagaaatta
    31981 aaaaagttca tagatggaaa tttgatgatt tagcacataa gatgatttca aagagggttg
    32041 taggaaaagt tcaacctgag aaaagtaagg aaagaagtga ctataatttt actataaata
    32101 taaaaggtga taattttgat gtaaaagttg atacaatggg aaaagattat gtaaaagtta
    32161 cttctaagaa aaatgtatct tactatgagg ttcatacaag tttatttgat taccttaaaa
    32221 atgagatatt tgaaattgga aagaaataag actttaagaa ggctatcaaa ttagatattt
    32281 gatagcctaa attattttat atattatttt tcaaccaaca agtctgcaac cttataaatt
    32341 ggaccagcac cagcagttat tactaaatca ttatccttaa cattttcacg taagtatttt
    32401 actatatctt caaattcttt tatatagatg gcatctacat tgttttgata taatttctca
    32461 accaagtcct tagaatgtat atctcctggg tctttttccc tagcagcata tatatctgtt
    32521 atgataactt tatcagcagc atagaatgcc tctgaaaatt cacctaaaag agattttgtt
    32581 ctagtataag tatgtggctg gaagatacac cataaagttg atttttttaa ttttttggca
    32641 gcagctaaag ttgcttttaa ctcagttgga tgatgtgcat aatcatctac tactaaagca
    32701 ttcttatagt accctttagt ttcaaatctt cttccgacac ctttataaat ttttatattt
    32761 tttcttatag tctctaagtc aataccagaa acaagagctg ccattatggc agaagaagca
    32821 ttgtatatgt tatgaagacc atatacagaa agttcaaatt ctcctaaatc tcttccttca
    32881 tattctattc taaatattcc atgaccacta ttgtcaaagt gaatatcttt tattacagca
    32941 tcattgtcag aatctctgcc gtattttata atagtagctt taacatcata caatatgtca
    33001 tcaatatttt catcatcgcc atttattatg aaatagcctt ctgggggtaa taattttcca
    33061 aatttgttaa aagaagcctt gatttcatct attccagaga aataatcaag atggtcttct
    33121 tcaacattta aaactataga tatctttggg ttaaaattaa ggaaactatc tacatattca
    33181 catgcttcag ttataaagtg gttggaatta cctatcttaa cattaccacc tatcatactt
    33241 aagttaccac caactagtat agttgggtct aagtctgcat attcaaagat tgtagataac
    33301 atagatgttg tagaagtttt tccatgtgtt ccagaaactg ctatagaatt tttatattcc
    33361 ctcatgattt ggcctaaaaa agttgctctg ttcattacca atttattttt ttctttagca
    33421 gccacaagtt cttcattgtc tggatgaact gctgctgtat aaacaaccat atttacatca
    33481 tctgatatat tatctttttt ctgaccaata taaatagttg ccccttggtc cctaagtttg
    33541 tctaataggt atgattcgtt tgaatccgaa cctgaaactt gataaccttt attgatacat
    33601 atttcagcta atgcactcat gctgataccg ccaattccta taaagtgtat attcataata
    33661 aaaccacctt tctttttaat taagtcctac aatatgaact atttctgtgg tataataata
    33721 taatgttcaa tattttataa ttaatatgca tataatatta tatgtatttt atttttgaat
    33781 ataataaaac ataagtaata ttataccaca ataagaattg ttatgcatta gttagtttaa
    33841 cgttatataa aggtacttgt aggaggaaat aataatgaaa tttaaaagaa cagagagaat
    33901 tggagcaata gttaaaatac tgtctgataa tccaaataaa atatatactt taagttattt
    33961 tacaaatcaa tttaatgcag caaaatcaac aataagtgaa gatttattag ttgtaaaaaa
    34021 tgtatttgag aagctacatt taggtaaagt tataactatt tcaggagcag caggaggagt
    34081 aaaatatata cctaaaactt ctatagcaga aaatgcagag ttcttaatgg aattatgcga
    34141 gagaatatgt gacaagtcta gaatactatc tggtggtttt ttatacttga ttgacctaat
    34201 ttacgaccct acaatagctg ctaagatagg aaagatattc gcatcaaata ttgagtatgt
    34261 agatgcagat tatgttgtga caatggaaac aaaaggtata cctatggcac ttatgactgc
    34321 aaaagctatg aatttacctc tagttataat aagaaaagat ataaaggtat cagaaggtcc
    34381 tacacttagc atgacatatg tgagtggaaa cagttctaaa gttgaaagta tgagtttgcc
    34441 aagaaaagct cttaaaccag atagtaaagt tataattata gatgatttca tgaggggtgg
    34501 aggtactata aaaggaatgg tagaccttat gaatgaattt ggtgcagagg ttataggtac
    34561 tggagtattc atatctacaa cgaatccttc agaaaaaatg gtaaaagatt atatttcatt
    34621 gattcaattg gatgttaatg gagataaaat agtagtagaa ccaaacttaa agacttttaa
    34681 agatgaatat agaaatgaag atttagacga agaagaagat tcagaatttg aatttgagat
    34741 agatgaagat taataaaaaa aatatttaga aaaatatgta aaaataaaaa gaggatatcc
    34801 ctagttgttc atagaattat ttaaaaaaca gtttatatta atttattcca gcgataataa
    34861 ttttaatata aattaatttc tgtcaaaatc aaagggggat attttggtat gaagataact
    34921 gacgtaagag taagaaaatt aacagaagaa ggtaagatga aatgtatagt ttcaataact
    34981 ttcgataatt tgtttgtagt gcatgatata aaagttatag aaggccataa tgggctattt
    35041 atagcaatgc ctagcagaaa agtaggcgaa ggaaatttca gagatatagc tcatccaata
    35101 aatgcagaaa tgagacaagt tttagaagat gcagttttac aagcgtatca tgaagcatta
    35161 gttcaatggg aagtagctgc tgaataataa taaatatata aaatggagag agcccgaaca
    35221 tttaggctct ttttaaatgt agaatttcta ttaaaatatg tactttttag taaaaaagtg
    35281 ctatattatt agtgataatg tatatgttgt atacaaattg ttagataaat gtattataat
    35341 gtatattgat taagagaata atacgaataa aattaaatta gattgaatgg agtgtatcaa
    35401 tgaactttaa agctataatc cttgctgctg gcaaaggaac aagaatgaag tctaaatacc
    35461 caaaagttat acataaagta tgtggaaaag aaatggttaa ccatattata gatgtttcaa
    35521 aaaaatcagg ggtaaaagat actgtcgtga ttttaggaca tgaagctgat gtagttaaag
    35581 aaaagcttgc agaagaaatt ataatagcca tgcaaacaga acaacttggg acaggacatg
    35641 ctgtaaagat ggctaaagaa tatattaatg atgaagatac aatagttgta ctttgtggag
    35701 atactccact tataaaagaa gagacactaa agagactatt tgaatatcat atagaaaata
    35761 aatatcatgc tacagttctt acaacaagag ttggaaatcc aacaggttat ggtagaataa
    35821 taagagataa gaagggtgac cttcttaaaa tagtggaaca aaaagatgca aattcagaag
    35881 aaaagatgat aagtgagata aactctggaa tttattgttt taatggaaag agtcttagag
    35941 aagcactaga tttgctaaat aataacaatt cacaaggtga atattattta actgatactg
    36001 ctaaaataat gagagataaa ggattaaaag ttggtgcatt tgcaggttca actattgaag
    36061 aacttatggg cgttaactca agagtagaat tatcaaaggc agaagaaatt atgagacgaa
    36121 gaataaatga atctcatatg gtaaatggag taactataat agacactaac tctacctata
    36181 tagaatctga tgttatgata ggcaatgata ctataatata tccaggtgtt atgttacaag
    36241 gaaaaacaag gataggttca gattgtataa ttggaatgaa ttcatctata acaaattcag
    36301 aaataggtga tggtacagaa ataaaaaatt caactataat tgatagtaag gttggagaaa
    36361 attctactgt tgggccatat gcatacttaa gaccaaagag tgacttagga aataatgtaa
    36421 aaataggcga ttttgtagaa gtaaaaaatg ctattataga agatggctca aaagcatctc
    36481 acctttctta tataggagat gcacatgtcg gtaaaaatgt aaatattgga tgtggagtag
    36541 tatttgtaaa ctatgatggt aaaaataaat ttaaatcaat agtaaaagac aatgcgttta
    36601 taggttcaaa ttctaattta gttgcaccag tagttgtaga agaaaaagga tatatagcaa
    36661 caggttcaac aataacacat gatgtcccag atggtgcttt ggcaatagca agagaaagac
    36721 aagttatcaa agaaggatgg gtagaaaaaa agaatcaaaa agacgaccaa agtaagtaat
    36781 tatgtagttt attattttgg ctaaaaaatt tagctcgaaa ttattataaa ttatattcat
    36841 tagtatttta aaattttcag gagggttaca taaatgaata ctagcggaag cgagattaaa
    36901 attattgcag gtaattcatc gaaagagtta gcacaaaaaa tagctgacta tataggtgta
    36961 tcagtactag attgtgaagt aggtacattt agtgatggtg aaatatgtgt aaacatgaat
    37021 gagacagtaa gaggttgtga tgtgtttgta gtgcaatcta ctaacagccc agtaaatgat
    37081 aacttaatgg agttattaat cttaattgat gcgttaaaga gagcatcagc aggtagaata
    37141 acagcagtta ttccttacta tggatatgca agacaagaca gaaaggctaa ggcaagagat
    37201 ccaatcactg ctaaattagt tgcaaattta ataactgctg ctggagcaga tagagtatta
    37261 acaatggatt tacatgcagc tcaaatacaa ggatattttg atataccatt agaccactta
    37321 ctaggtggaa caatattagc aaattatttt aatgaaaaga aaatagaaga tttagtagta
    37381 gtatctcctg acttaggaag tgttactaga tcaagaaaat ttgctaatac tttaaatgga
    37441 gaagttccaa tagctataat agataaaaga agaccgaaag ctaatgtatg cgaagttatg
    37501 aacttaatag gtgatgttaa aggtaaaaat gttatactat tagacgatat gatagataca
    37561 gcaggaacaa tagttaatgc tgcaaatgca cttaaagagt ttggagcaaa agatgtttat
    37621 gcttgttgta ctcatggtgt gttatcaggt ccagctattg aaagaattgc taattcagaa
    37681 ataagtgagt taatagttct tgatactata caacttcctg aagagaaaag aatagataag
    37741 ataaagataa aaacagtagc tcctttattt ggagatgcta taagaatgat attctctaat
    37801 gaatcagtaa gtaaattatt ctaatttatt gtatttatga gagttgttta aaaggatata
    37861 aaccttttga gcaactcttt tttgatttta taattatgga atgttatttt tttcttgtta
    37921 gaaaggtata tattattgta aaaagagatt atagtttaaa attatgtata tttaagtaaa
    37981 ataaacttaa taaagggcat attattcaaa atattatgaa tataaaaaat attacaaaaa
    38041 agtattgaaa aaattcagat tatgtagtat tatgtaaata taaataaaga aagaaagagg
    38101 tgtttccaat gggaaggtta gaagatgaac ccctaataat taaatgattc agtcacaatc
    38161 taaagtgaat ataaaaatct attgaaagtt tatttataag aattgaaaat agtatctatt
    38221 ctatctttag tgtttgtgag agggttctgg attatataag attactgtaa agaagtaatt
    38281 ttgcacaata agcatatctg taaatgaaga gtttcgttta tataatgatt gtggctgaat
    38341 cataactata atagatagaa tgtttataat agatgatttt ataaaatact atattgtaat
    38401 agcttttagc tttcaaataa atattagcaa aggatggaaa tgacaatgat aaaactaaat
    38461 gataatttat aaatatctcc ttacgatata taataattgt agggagatgt ttcttttttt
    38521 tgtagagtat aatttttcta gaaattctgt ttcaatatgt aaaaagttgg tatatataaa
    38581 tagtataaac agtgttgcta aaatatggta gatattatat aatataaatg gatatgtata
    38641 tacattatga gttatataat ttgaatttaa taaaatagaa acgttgattt atgttctgta
    38701 atgtgggcac cttggagcat attgagttag tggtgcaacc ggctatgaaa ttgtatttat
    38761 ttataaatac tattattttc atagcttttt ttatttaaaa aatggttata tgttagaaat
    38821 aaatttggtt agtacgttta aataatttta cttagatttt taaccagata tattataagt
    38881 aagtattaat taaaaaattt aagggggaat aaaaatgaag ttaaaaaaga ataaaaaagg
    38941 tttcacttta gtggaattat tggtagtaat tgcaattata ggtatattag cagtagtggc
    39001 agttccagct ttatttagta atataaacaa ggctaaggta gcaagtgttg agtctgatta
    39061 tagttcagtt aagagtgctg cattatctta ttattcagat actaataaga taccagttac
    39121 accagatggt caaactggtt taagtgtttt agaaacttat atggagtctc ttcctgataa
    39181 agctgatata ggtggagaat ataaattgat taaagttggt agtaaattgg tattacagat
    39241 aggtacaaat actgagggag ttaccttaac agaagcacaa tcagcaaaat tattgagtga
    39301 tataggtgaa aaaaaaatat atacaagcgc tacaacaaat agtttgggag atccattaac
    39361 aagtaataca aaaatagata ataaagttct atatatagta cttatagata atactgtgat
    39421 ggacacaaca aaatagttaa aacaatattt ttataaagaa tattgtaaat ttaatgaaaa
    39481 atataatata aaagacagga agaaaatctt cctgtttttt tatactattt tctttaatgt
    39541 tcaattatga atgatgatat aattgagata gtaaaggagt gaaacctgtg gctaaaaaag
    39601 ttagaatagg agacaaactg gtcgaaaaag gatatataac agaagaacag cttaaatggg
    39661 cactatcaga acaaaaaaac agtggaaaaa gactaggaga atttctagta caagaagggc
    39721 ttatagatag taacttacta ataagtgtat taaaagaact cttggatata gaaagtatat
    39781 ttttagaagg gacagaaata gacactttag ctacaaaaat ggttccagaa aatatatgca
    39841 aaagatatac tgtatttcca tttaaaattg atggaaataa aatatgtcta gccatgtcag
    39901 acccacaaga tagagaagca gttcaagatg taaggcgtat gtctggtaaa gacgtagaga
    39961 tatttatatc aagtacagaa gatataaaca aagcaatagg tcatgcttat gcacattcag
    40021 aaataaataa ggcaatgact gagtacaaca aaaatagaac tggtggagta agagaaacag
    40081 taatacttga agaagatgta aatgctgctc caatagtacg attagtaaat aacatactag
    40141 aaaatgctgt tagaatggaa gcaagtgata tacatataga acaaagtgaa aattacatgc
    40201 gtgttaggtt taggatagat ggaatgttaa gagaatatat gaggatgaac tcagcaccat
    40261 ataaggcagt aatcagccgt atcaagataa tgtcagatat aaatatatct gaaaagagaa
    40321 taccacagga tggtagaatc tatttaaaag tagataataa acccatagat tttagggttt
    40381 ctacaatgcc aactaacagg gatgaaaaga tagctatgag agttcttgat aagagtaatt
    40441 ttatggttag taaagaagta ctaggaatag acgaacatgg ctctaagata tatgatgaat
    40501 tgataaacac tccttatggt cttatattgg ttgttggccc tactggaagt gggaaaacca
    40561 ctacattgta ttcaatgtta aatcaactaa atacagaaaa tagaaatcta ttaacaatag
    40621 aagaccctat agagtatgaa ttacctggtg taaatcaatc tcaaataaat gaaaaggcag
    40681 ggcttacttt cgccagcgga cttagagctt ttatgcgtca agacccagat ataataatgg
    40741 ttggagagat aagagatact gagacagcag aaatagcaat tagagcttct cttacaggac
    40801 atttagtttt aagtacatta catgcaaata cagcagttgg agcaatttca cgtcttttag
    40861 atatggatgt ggaaagtttt ttaataactt catctgtttt aggtgtaata tctcaaagac
    40921 ttacacgaaa aatatgtgag cattgtaagg tttcatatga agcagatatt ggagaaaaaa
    40981 aggctcttgg tattgatgta aatgaatcag taactattta tagaggaaaa ggttgtgaaa
    41041 ggtgtaataa tactggatat aaaggacgtc taggtatatt tgaaatgctt gaaattactc
    41101 cagaaataaa agagttaata gattcatctg caaatcaaag agaaatttta aagatggcta
    41161 gaaaacaagg tatggttagc ttaaaagagg atatagttaa aaaagtttta aatggaaaga
    41221 caacagtaga agaaatgatt agaataattt tgatgactga ttaaaggatg atattatgaa
    41281 aagttttaaa tacacagtaa taaaagagga cggaaaaaag caaactgatg tgattgaagc
    41341 caacgatttt aatgaagcta gaaatcttct tagaaagaga aatcttagag ttattgaaat
    41401 caaagaaagc aaaaataaaa atataagatt atctagtaga aagagaaaaa aagacttggg
    41461 agctgaccag ataagccact tttgcagaca gtttgctatt atagtatctt ctggtataaa
    41521 tagtatttct ggattagaaa cattagctag aaggtcaacc aacattacat taagagaaga
    41581 aattaatcgt atagtggcag aaataaaagt aggttctact attgcagatt caatgctttc
    41641 atcaaaatca aagtttccaa agttactcgg tgctatggta gctacaggtg aagctacagg
    41701 taaattagat gaagtattaa aaagtatggc ttcattttat gcaagtgaac acagggttaa
    41761 acaaaagctt agaaatgctg caacatatcc attaatagtt ttgatttctt catttataat
    41821 gatttttata tttacaacat ttatggtacc taagatgatt aattcaatta caacagtagg
    41881 agcaactctt ccacttataa caagaattgt tatggggttt ggtatgttta tgaagaagtt
    41941 ttggataata gtactcttag ttattatatt atttatctat cagtttaaaa aatatctaaa
    42001 aacgtcagtt ggaagggctc ataaagatag agttataaat aagatacctg ttttaggaaa
    42061 aggaataaat tgtatggtag ctacacgatt ttcaagagca ttgtatctat ttgtatcaac
    42121 aggataccca ttagttcaag ggcttgatta tattatagat agtgtaaata acaccatggc
    42181 agagaagatt ttagcatcag ctaaagatgg aataacaaga ggagaaggct tagcagaaaa
    42241 tttagagaga tatacgtatt ttgactctgt gttggtacag atgatagcta taggggagca
    42301 gacaggggaa ttagagaata taagtagaca gatggcagaa ttttatgagt atgaatccga
    42361 gatttattta aataggatgg cctcaatgat agagcctgtt ttaataattg cagttggtat
    42421 tatagttgcg atactggttg tatcaatatt tatgccaatg cttagtatat atgatgccat
    42481 gtaggaggga aaggacaaat gaacaaggtt tatgtatcat attatggcga ttctatttcc
    42541 atagttgagg gcagatataa acacgataag gataagtttt atgtaaaaaa ttttaatgtg
    42601 ttttcaatag aggatattgc acaagatttt tctaaggaaa agtatgctct attgagatac
    42661 gcattagaaa atgttaagtt aaaatcaaga catgtagttt tttgtttaaa tacaagagat
    42721 gtaattttaa aaccccaaaa acttcctaat atggacaaaa aggatttaga tggatttatg
    42781 aagctagaga tggacgaaat gatggctttg gagtcagatg aatatgtatt ttcgtatgaa
    42841 gtatctagtg aaacacctga taattcagat ggcgatgaat caagcttaaa tcttatcatt
    42901 ggagctatac aaaaggaaga ggtaaatgca attgtagaga taatgcatga atttgattta
    42961 gtattagata gaatagatac attatcaaca gcttacttaa gaatgcttaa aaatttagac
    43021 tacaatgata taatggtaac caatataagt gacaatagca caattataaa tatatataag
    43081 aaagatactt tatttattag tgataatata cctataaaga taactgctaa agatatggac
    43141 atgcaattat taaatgtagt agaagaatca aaaggtctta tgaattacta ttcgtcaaga
    43201 aactttggta aggttacgga tactatatta atattaggaa aaagatattc caataaatta
    43261 atttatgaaa cttttagctc tgcattttca agctatgttt ctcaaggcct tactgagata
    43321 atggatatat ctgatatgat aactggagat atagatgaag atgatataaa ttcaattgta
    43381 gagcttttag gaagtatgat agaacctaaa gggaaaagag attttgaaaa tataaacttt
    43441 ttaccaatgg atatacttag aaaacagata aaagctaaac aaatgaaaaa catactgaaa
    43501 attgctccaa tagttatttt gattcttgct ataccttatt tatgcttaat tttttcaaat
    43561 aatttagcaa ataaggaact tgaaaatgtt aatggtgaaa taagaaatat tgaatctgca
    43621 tattatcaga ttggaaatat agaaaaaatg atacagagta aaagcgaaga aataaaggta
    43681 tatgatatgt taattgggaa aaaggtaaag tgggaaaatt tattggatga tatagataaa
    43741 aatactccaa gtaaagttga actaacaagt ttatcaacaa cttatcaaaa tcttggaact
    43801 aataataaag ctgataattc aaaaagtaat aagactacaa cagataaatc aagtaacaat
    43861 gaaacaaaat caagtacgaa aagtgatagt aatggagata aaacagataa tgatttaaat
    43921 gaagataaga ctacaaatgt gtcagaagca ttaactggaa atagtgagac taatagtaat
    43981 aacacggata aagatgataa aactccattg tatgataaga taccaaatgt tataaatata
    44041 gaaggaaatg ctaaagattc ctcttatgta ggtcaatttt tatataaatt aaagggatta
    44101 tactatttca aggatgttaa attacatagc ataaaaagta atgcagaaga ttctaactat
    44161 acatttagta tgacattata cctgaaagaa ggtgtattaa ctaatgaata aagatatatt
    44221 taaaaaagat ataaaagata tatttaaaat ggaagttagt ctaaaaggga ttcttataaa
    44281 ggttataatt ttattagcta ttttatcata tggttatttt ggactttacc ctcaatatca
    44341 gaaatatatt gctacaaaaa attctgtaaa acaggctact gaaaaattaa atatatataa
    44401 agagaaaact gcacttatgc caaaatatga aaaacaactt gaagaagttg aaagtgaatt
    44461 aaaagaaaaa agcaaaaatc ttttatatga tatgcaagat ggtctttttt taataggttt
    44521 agataaaaaa atgaaggctt ataatattga cttaaccagt tatgacgttg gaaatgttaa
    44581 agaatacgaa catttttatg gtatatcaac aacaataagt gttagaggtg attatagaaa
    44641 tgtcaaaaaa ttaatggctt atttagaaga acaaaaaaat gttactcaaa tactagatta
    44701 tacaatgact tcatatatag aaccagaaaa agaagaggaa gaaacaacaa acaataagga
    44761 tttaattaaa aatgtgaaca taaataaaga tacaaaaata tactgggtgg aaggcgaaaa
    44821 taagtggcat ttatataagg attgtccatt gataaaagag ggagagatta taaaaaatga
    44881 caaactttta gataggtcta ctaattatct atgtaatact tgtgtactta gagctgcaac
    44941 agaaaaagaa gcaaaaaaag aagtcgtagc tccaaaggca gaaggtgtag tagatgctac
    45001 atttaaattt ataatgtaca ctaaagagaa tactacaatg atacttgata cagataatcc
    45061 atcttcatgg aggccaggaa aatataatcc atttaagtct agtgcgaaat aaagctaagt
    45121 aagctttaaa gataggtgat gagtttgtac aaaaataatg aaaaaggtct tactttatta
    45181 gaagtaataa tagctgtttt tatactgaca atagttttaa gtatttctta taaagtgttc
    45241 aatggtataa catcagcagt aaaaaagcaa cagattatta cagatgctca agtaaatatt
    45301 aatctaatta ataagtatct aaatagagat ttggaaaact gtaaagaact aactaaaact
    45361 ggttcaggta ataattatga atacaatata gagatgccag ataatgttgt aaaatatgaa
    45421 gtttctatag aaactaaaaa aaatacagag gtatattctg taacgagaat ccaaaacaat
    45481 acaattgata cagaaaatga agttagagaa gaaataatct ataatcaacc actagttcaa
    45541 aacaataaag aaatgaagga aacaccattt aaaatagaaa agcaaactgg taaatctatt
    45601 tatactgtaa gtatatacta taatgaatca gtgcaagaaa gtcataaaaa tagcaattta
    45661 aataacaaaa cttatacatt tgatgttatg tcaagaatag ggtaataaga atttattaaa
    45721 aaataagtag gttgataaaa tatgagtaaa aagaatagtg aaagaggatt ttccttaatt
    45781 gaagtgttag tagctatggc tattatggga attgtactat ttgcattttt taatattatc
    45841 aatactaata acaaagcaaa cactaaaaat gacacagata taacttcctt aaactatgtt
    45901 caaagtgaaa tagaaaatct aagagaaaag ataaaaagtg gagaatttga ttttgatagt
    45961 ttagataaac tagaagatgg aactgtcgta tatgaaaaat taatagataa atcaaaaaaa
    46021 gttgtatatg ataaagttct tagtgaaggt gatgtgagct tatatgatac tccatatgaa
    46081 aagattacaa caataaaaga tgaagatggt aatttaatcg acaaaggaaa tattacaaat
    46141 aagataaaga ctattgtaga agataaaagt ggtcagatat ataaaatagc tgtaactggg
    46201 aaaagcatga atgactattc aagtaaaaaa gaggttaaaa ttgtaactga aatatttaaa
    46261 gataaataat tttacttggg ggtgagattt tgaggaagtg gaataaattt aaaagtgaaa
    46321 gaggggcagc tttagtttta gttttggttg tagtagcatt gctttctatt gttggattga
    46381 tattttcaaa tcagatagct aatagaataa aatctacaaa gactactaat gaaggtatac
    46441 aagcaaagta tttagcagag acatgtgtgg aaaatagtat tgataaagca tatgaaaaat
    46501 tgtatgatga gcttgagaaa atggataatg agtttaaaag tgaaaatcaa gaaaaatcca
    46561 tatctaggtc aaaattaaga aatatatcag atgaagattt taataatcaa gatgaggaaa
    46621 atattgaagc agaaagactt ggatatatga ataatataaa tttctattta aataaagctt
    46681 cttcagactt ggaaaaagct agtatggaat tgaaaaagct atatgattta gatatgttgg
    46741 actatagaga cattgaatat gtagatgcaa atattatttc acatagagat tctatcttag
    46801 aaatttgcaa gaattatact tctggagata ttagtaaaat aaatgaatat attctgaaag
    46861 aagatataga ctcaactaca ttgattgagg caaagttagt gaataatgat attcttttaa
    46921 aaatgttttt agaagaaaat aaaattgaaa atgaacattt aaattcagcc ttttcacata
    46981 cttataaggc attagataac atttctttgg cgatgcaaaa tatgattgag tatagacata
    47041 cgtttcatat agatgagcca aaagtagaag tatctaatgg gattccagac tctcaacaat
    47101 attatgaact aatacaaaat cctataataa atagtatgga gtatagctgg aatagtaaat
    47161 gggatacatt agaaaaccta ttggaaattt taccaaatca aactcaagga tttaattctt
    47221 taagagttca tttgagaaat aatgtaagaa aatttgagaa gttaagcgat aatatatcta
    47281 gtggtaaaaa aaatacagca aaaaatttct taaagtataa agagttattg tatgaaatat
    47341 cagaccaatg taatcaacta aaaagtatgt cttatgagaa aatacctgtt aaatatgata
    47401 acatggcttt gataacaact tttgactata tacaaaatga gcttttagca gagataaaat
    47461 gcagattaaa agaattaaaa ccacaagaaa ttgataaaac agaaggtatt actataaaaa
    47521 taccttttta taaggctgac tacgacatga caaaagaagg atggcctaaa ttaaaagaaa
    47581 atggttcagg ggcggagtta agcttaatgg taactggtga taaaaatgga ataaaagaag
    47641 tagaagttac agatggtaaa aaaaatatta ttggtttagg tgttgaagaa aattcaaatt
    47701 caaagtataa ggttgacgcc attgtaaact ttaatctaaa tatagataca aatgtagttg
    47761 gaaattatga tataaaagat aaaattttga ttaatcatga tataagttca tacaaaaaag
    47821 taaactaaat ataagaagca acttagtata aataaataat aaaataattt tattatttac
    47881 tactaaaaaa ataagtaaac taatagaaga tatggagagt aaatattatg tatatttatg
    47941 atttattaga gcaaggtata agactaaacg catcagatat acacataaca gttggaacaa
    48001 atcctgtagc tagagtaaaa ggtggatttg taaaactaag tgaacaaata ttgacatcag
    48061 aagtaacaat gcaaatggca aaagacatag caggggaatc tatgtttaaa gtaatagaag
    48121 aacatggaga agctgatttt tcagcttctc taaaaacagg agaaagattt agggtaaatg
    48181 catataggca aaaaggaaat tacgcaatag caataaggac tataacagca gaaattccaa
    48241 catttgaaaa attaggcctt ccagagagta taaaatcttt tactgaaaag cataaaggat
    48301 tagttttagt tacaggtcca acaggaagtg gtaaaagtac aacacttgca agtatgataa
    48361 atataataaa tgaaaaacaa caaaaacata taattacact tgaagacccg atagaatatg
    48421 tacatcacca taaacaaagt ttagtaaatc aaagagaagt aggaactgat acagaaagtt
    48481 ttcattcagc ccttagagct attttgcgtc aggacccaga tgtaatacta ataggagaga
    48541 tgagagaccc tgaaactgtt tcaatagcat taacagcagc agaaacaggt catttagtat
    48601 tttcaacact acatacagtg ggggcagcta agacaattga tagaatagta gacatgtttc
    48661 aaccatccca acagcaacaa ataaaaacac agttatctac agtttgtgaa ggtgtggtat
    48721 cacagcagtt acttcctaca gcagatggga aaggcagaat agcagcaatt gaattgatgt
    48781 ttgctactcc agcaataaaa aacctgataa gggaaggcaa aacatatcaa attccaaaca
    48841 tgatacaaac tggagttaaa gtaggtatga aaactatgga ccaagattta atggaacttt
    48901 ataaaaatgg aaagattaca aaagatatgg cacttagtag gtgtactgac caagagttta
    48961 tgacaagaat gataggtgga gtaaactaca atggatatta taatcgttaa tctatatgta
    49021 tttatagtgg gtatagtgtt tggaagtttc tttaacgtct gtatttttag gattccagaa
    49081 ggtatatcta tttctagacc accttctcat tgtatgagtt gtaatactag actaaagcca
    49141 atagacttaa taccagtgct aagctattta atgagtggca gaaagtgtag atattgttat
    49201 gagaaaattt ctagtagata tgctatagtg gaattaatta caggactttt atttttaaca
    49261 gtatttatgt tatatggaat atctacatca actatttatt atttggttct tgtgtcttta
    49321 ctgattataa ttacatttat agatattgac cactttataa taccagataa aatattggtt
    49381 tttggagcta tattttctat gatttttaac cttttattta aagaaattcc agttaaggat
    49441 tcaattctag gtgtttttat ttgtggagga agtgtctgga ttatagttct tttgattgaa
    49501 tttgtaataa aaaaagagtg tatgggtgga ggagatatca aactatttgc aatgctagga
    49561 ctttacatgg gtgttaaaaa tggtcttttg acagccttac taagcgttta tgtaggagca
    49621 gtctatggaa tctgtgtaat aattataagt agaataaaag gaaaggaata taattctgtt
    49681 ataccatatg gaccttttat atctattgga gcattaataa caatcttatc tggaaagcaa
    49741 ttacttgaac tttatttttc tatggttata tagatgatag tcaagttaaa taaagtttta
    49801 atttaaaaaa atgaattaaa gtatttaata aggacaatat tattattaac cctattacta
    49861 aagtgctaca aactatggag tatataataa taatttcctt attttttgca catttgataa
    49921 ataaatctct atgtgttttt tgtgatagag aaaagaaaaa tttatataat acgtttttta
    49981 tttacataat aactgtagtt ttatctgtat taatatatct aaaatttggg attagtgtag
    50041 aatgtgtaca atatatggtt ttaattccat ttttaataat tatatccatt gtagattact
    50101 acacaatata tgtatatgat ataacaatag ttagtggtat aatagttcaa ggtataattt
    50161 ttttggcctt tttcaatata gctcaatttg attatataaa tcatatattt ggactattga
    50221 taggctttat tataccttat attattgcta aactaacaaa aggattaggc tatggagatg
    50281 taggtctcta tagcttatgt tgctttgcat tgggaaataa ttatgggttt tatgtgatag
    50341 ttttatcatt tattttagcg tttttgtttt ttattatttt atacataact aaagtattta
    50401 aagatgtaga tataagaaag caaattcctt ttacaccttt tatttccttg tcaacaattt
    50461 taataatatt tacagagtat aatatattta atttttatta taatttgtta tacaaattta
    50521 tataacagga ggtaagaaat gtacgtagta gtagggttag gtaatccagg aaagaagtat
    50581 gagaagacta gacataacgt tggatttgat gttatagata ttcttgctaa agaatacaat
    50641 attagtgtta ctaaaataaa gcataaagct ttgattggtg aagggagagt aggtactgaa
    50701 aaagtattat tagttaaacc acaaacttat atgaatttaa gtggagaaac attaatagat
    50761 atatataaat attataaggt tgatttaagt aatatagtag tagtatatga tgatatagat
    50821 ttagaagttg gaaagatacg tataagaaaa aaaggaagtg gaggaactca taatggcatg
    50881 aaatctataa ctaagtgcct aggttcaaat gactttccaa gagtgagagt aggtgtatct
    50941 aaaccagaag ctggtcaaga cttagcagac tttgtacttt ctagatttag aaaagaagaa
    51001 tctgataaca taaatgaagc attagaaaaa gcggcagatg ctattgactc aataataaga
    51061 gaaaatatag atatgtctat gaacaaatat aatggatagt gagagggaga tttaaatgaa
    51121 tgatgttttt ttatatcctt tgcaaaattc aaaagagtat aaagatataa taaactgtat
    51181 aaaaaataca aaaggctcat tattggttaa tggactttta ccagtacaaa aacctcatat
    51241 atcgtattct atatttaatg atttatcacg acaaatgatt tttataacga gtagtgattt
    51301 agaagcaaag aaagtatacg aagatttaag tttttatatg gaagataaag ttgaatattt
    51361 aggttttcaa gatatttatt tttatcactt ggatgcaaag gacagaaacg aagaagcaaa
    51421 gaaattaaaa gtattgttaa aactagcaaa taaagaaaaa atcattttag taacttctat
    51481 tgaagcagtt ttaagaaaat acataccaaa acaagttttg ctcgatagtg tatctcatta
    51541 taaggtggga gatagcttag acttagaaaa gttaactgag aaattagttt cattgggata
    51601 tgaaagagtt tcaaaaatag aggggtttgg tcaatttagt ataagaggtg gaattattga
    51661 tgtattttca cttgaatata caaatccaat tcgtatggaa ttatttgatg atgagataga
    51721 ttccatacga acttttgatg tatattcaca aaaatcaatt gataaattgc aacaattctc
    51781 tataactcca tctagggaat ttatttatcc cgaaaaaact acagatgcat tagttaaatt
    51841 aaaaaaagaa acaactaaaa atactgatga aggtacattt caaaatatag attatatatc
    51901 aagtaagact tattttgaag gtgtagagaa ctatatagat tatatttatc cagaagaaaa
    51961 caaaagtata tttacttatt tagcagatga tgcaatagta tttatcaatg atataacgag
    52021 acttaaagaa agatgcgaaa attatataaa tgagtttaga gaaaattata aattaaatct
    52081 tgaaagaggt ctggctatta aaaaccaagg taaattgtta tatcactata cagatttaga
    52141 gtacttagta aaagacaagt ctgtggtatt aaactcatta ttgccaaagt ctataaataa
    52201 cttttctata aaatctataa taaattttga aagtagagaa gttcctacat ttaatggaaa
    52261 ggtagatttg cttgtagaag aattaaatcg gctgaaatat aatggataca aaataatttt
    52321 agcaacaaat acattagaaa gagcaaataa attaggaaaa gatttattgg acaaaggctt
    52381 agaaacgacc atttctaaag atagagatat tgaaattaaa tcttcacaag ttataattgt
    52441 acctgcacac ataaacagtg gttttcagta taaatctata aagtttgttg ttataacaga
    52501 taacgaaatg ataggtgttt ataaaagagc gtctaagact agcaataaaa aagttaaaaa
    52561 gggaaagaaa atagaatcct ttttagattt aagtgttgga gactatgtag tccatgaaaa
    52621 tagtggtgta ggtagataca cagggattga acaaattaca gtcaatgcta ttaaaaaaga
    52681 ttatatgaaa atagtatatc aaggtggaga taatctatat gtgccaatag accagatgga
    52741 caaagtacaa aaatatattg gtgcagaagt agaaaaagtt aagttaaata agcttggaac
    52801 aaatgagtgg acgaaagcaa aagcaaaagt taaaaaagaa attgaagata tgacaaaaga
    52861 cttgattgag ctttatgcaa aacgtgaaaa aatacaaggg tataagtttt caaaagatac
    52921 accttggcag gcagagtttg aatcgttgtt tccatatcaa gaaacagaag accaattaaa
    52981 ggctatagaa gaaactaaaa aagatatgga atcaagtaag gtaatggata ggctagtatg
    53041 tggagatgtt ggttatggaa aaacagaggt agctattaga agtattttta aagcttgtat
    53101 ggaccaaaaa caagttgctg tattggttcc aacaacaata ttggcccaac aacattataa
    53161 tacattcaaa gagaggtttg aaaattatcc tttgagagta gaagttttaa gtaggtttaa
    53221 aacaccaaaa caacaaaaac agattattga agatgctaaa aaaggattag tagatatttt
    53281 aattggaaca catagaataa tatccaaaga tataaattta ccaaacttag gtcttgtagt
    53341 cattgatgaa gaacaaagat ttggagtaaa acataaagaa gctttaaaga aaattaaatc
    53401 tacagtagat gtacttacac tttcagcaac tcctatacca agaacattac atatgtcttt
    53461 aagtggaata agagacatga gtgttataga agaacctcca caagaaagac atcctgtaat
    53521 aacatatgtt acagagagta aggaaagcgt aattcaagat gagatagaga gagaattaag
    53581 tagaggtgga caggtatttt ttgtatacaa tagagttgaa cacattgaag aaatggcaag
    53641 tatgattcaa aaactcgtac cagatgctag agtggctgtt gcacatggaa gaatgacttc
    53701 taaatcatta gaaaatataa tcctaggatt tttaaataaa gattatgatg tactagtctg
    53761 tactacaata attgaaactg gtatggacat atcaaatgca aatacaatga ttatatatga
    53821 tgcagataaa atgggattgg ctcaacttta ccaattgaga ggtagggttg gaagaagttc
    53881 aagacaagga tatgcatatc ttttgtatga aaaagataaa actttaagtg agatagcgga
    53941 gaagagatta aaagctatca gagaatttac agagtttggt tctggtttta aaatagcaat
    54001 gagagacctt gaaataagag gagcaggaaa tattttaggt tctcaacaac atggtcatat
    54061 ggcagttata ggttatgatt tgtacgttaa aatgcttaat gatgcaatta aaaaagtcaa
    54121 aggtgaacct attgtggagg aaattgatgt tgaaatagat ttaagtgtaa atgcatacat
    54181 tccagataat tatatcaaag atgagttgat taaaattgaa atgtataaga aaatagcttc
    54241 tattgaaaac aaagaagaca tgttggatat acaagaagaa cttgaggata gattctctga
    54301 tatacctaaa ccagtccaga cacttcttac aatagcttat ataaaatcgt tatgtaagat
    54361 attaaaaata gaaaagataa gacaattaaa agatgaaata ttattagttc caataacaaa
    54421 gtatagaact aaacagaaaa taggttataa tatagttaca gaattagaag aattattaga
    54481 aaagatgtgc aaggtaaaat aacttgtaaa tttaagaagg gatgttttaa atttgaaaaa
    54541 agtaataaca ttggtaatag ctatgatttt ggtagtatct gtgactgctt gcagttctag
    54601 taaaggagaa actgtggcaa cagttgaagg tacaaagata tcatcagatg aatttaaaaa
    54661 aactatagct ctttataaag attctatgga acaaacttat ggaaaagata tatgggataa
    54721 ggaagttgaa aagggtgtaa aatacaagga caagtttaaa gatttaattc ttgaccaact
    54781 tataactaca gaagtaatat attctcaagc taaaaaagat aacttacttc ctaaaaaaga
    54841 ggatgttgaa aaaagtttta aagaattaaa agacgctatg ggtaaagatg aaaaatataa
    54901 agaacaactt aagaaattag gtatagatga tgagttttta agagaccaac aagagaaaga
    54961 tttagcaatg caaaactatc aaagtaactt tgctaaaaag actaaaatat cagatgaaga
    55021 aatgaaaaaa tactatgata cacataaaga tgaatttaaa aaagatgagg tagaagcttc
    55081 tcatatttta ttgaaaacag tagatgataa taacaagcca ctttcagata aggaaaaagc
    55141 tgaagctaag aaaaaggctg aagaggctct taaagaagtt aaatcaggtg aggattttgc
    55201 aaaagtagca aaaaaatatt cacaagatac ttcagcaagt gatggtggta aattaggatt
    55261 cttttcaagg ggtcaaatgg ttgctgaatt tgaagatgct gctttttcta tgaaaaaggg
    55321 tgaagtatct gatttagttg aaactcaata tggataccac ataattaaag tgacagacag
    55381 aataaatgag caaacatcat ttgaagatgc taaagaaact ataaaagacc aactgttgaa
    55441 aaataaatat caagaacaaa tagaaaaatt aactaaagaa gctaaggtag aaaaagatga
    55501 aaaagtaata aataaaatca caatctaaga cttaaaaaaa gagtaatatg cttaaaaaag
    55561 ctatatctgg ataagatata gctttttttg tatatttttc ttaacaatgg taaaaataaa
    55621 cttaaagtaa tttatggagg gattaaaaaa tatgaaagca acaggtatag ttagaagaat
    55681 agatgatctt ggaagggtag ttatcccaaa agagataaga aagacattaa gaattagaga
    55741 aggagaccct ttagagatat tcacagcaaa agatggagaa gtcatactta aaaaatactc
    55801 tccaataggt gaattaaatg aattttcgca agaatatgct gaaacattag ctgaagtact
    55861 aggatatgga gtgttgataa cagacttaga ttctataata gctgtgtcta agcttcctaa
    55921 aaaagattat aaagaaaaaa gtataagtga tgagttagaa gcaataataa gtgaaagaac
    55981 agtaaaatat tcaaaagata aaaacatttt accattattc aaggaagacc aaaaagaata
    56041 tactagtcaa gttatcatgc ctataattag tgcatctggt gactgtatag gttcaattgt
    56101 agttgtttca aaggataaag atacaattgc agaaagtgaa gaaaaatctt taaaaattgc
    56161 tgctaacttt ttaggaaaac aagttcaata attttatcat aaagaccttt tacatgaagg
    56221 tcttttgaag tttttgtgta aaatattgaa tatagcatta aaaatatggt atattaaagt
    56281 ttgttatata aacagtatgg aggttatgtt atgaacaata acaaaaataa agactccttt
    56341 ctaaaaggag cccttatact tgggctagca ggtgtaatcg taaaaataat gggtggattt
    56401 tttaggattc cccttggaaa catgattggt tcagaaggaa tgggatacta tcaggctgct
    56461 tatcctgtgt atactctatt tttaacatta gctactgctg gatttccaac agctgtggca
    56521 aaattggttt cggaaaaagt tgcaattgga aattttaaag gtgcaaataa gatatttaag
    56581 gtatcacata cagttttatt cattaccggt ataatatcat tttgtatatt attttttgga
    56641 gccgactaca tagtaacaaa cgtaatgaaa aatccaggtg cgttatactc tatgaaagcc
    56701 attgctccag cattactatt tgttcctgca atgtctgcat atagaggata ttttcaaggg
    56761 agacaagata tgactaagat tgctgtgtct caagttgcag agcaattttt tagagttgta
    56821 ttaggtctta ctttggccta cttgcttatg aagagtctag gtcagacttt tggtgcagca
    56881 ggtgctatat caggggctac aataggttca atagcatcta tgctttattt ggtgtttgct
    56941 tatatgctag ggagaaaaga gcgtagagca gagatagatg caagccaaag atttaaagat
    57001 gaaagagtgt cttatatttt taaaaagctt ttaactgttg ccattcctat aacaatagga
    57061 gcatcagtaa tgccacttgt aaatatgata gataatgtta ttgtaataag aagacttatg
    57121 gaagcaggct ttacatacaa agtggcaaat tcaatgtttg gtcaattaac aggtatggca
    57181 atggccacaa taaatttacc agcagtcata acaactgcaa tgagtatgag cttagttcca
    57241 gcaatttcta aagcatatgc attaggaaat aagtcaaaag ctagaaaaga tactaagagt
    57301 gcagttaagg taactttact tatagtattg ccttgtgcgt ttggtatggc ttctttagca
    57361 ataccaataa tgggtctttt atttccacat gaaccatctt ctgtaggaac tattttgttt
    57421 actcttactc catgtgtatt atttttagga ttaatacaga cattgactgg tataattcag
    57481 ggaatgggaa aaccaatagt acctgtaatt gctttatgtg ttggtatgct atgtaaaatt
    57541 gtaataagtt atactttaac aggtatacca gatattaatg tactgggttc agcatttggt
    57601 acagttacag catactttgt ggcagccatg attaacttac tatatgttaa aaaacacatg
    57661 aatgtaaact tttctaaaaa agaatttata ataaagccat ttataacagt tatgacaatg
    57721 tttataatgg ttaagttgag ttatggtgct ttagttggat tcttaggaaa cagcatatct
    57781 acaataattg caatatgtgt tggtggaatt gtatatgtag tagtaatact tggaataggt
    57841 ggaattaaaa aagaagagat tctaactatg ccaaaaggtg ataaattata taaattgtta
    57901 aaaaaagtta aacttataag ataatatagg aatatatatg caaataaagg aaatactata
    57961 caaatagtaa atctccttat ttgtataata atataaaaat aaagtgaaat ttgctaatag
    58021 gagtgatgtt atgggtaaga taagtattgt aggtcttgga ccaggagact attctcttat
    58081 aagccaaggt gtgttagaat ctttaataaa tagccctaaa gtttttttta gaacagagaa
    58141 acatccaata attgataaac ttaaagaaac tatacaatac acttctttag actactttta
    58201 tgaaaaagag gaaaattttg ataatgttta tttgaaaata tctgaattta tcatagaaga
    58261 atcagcaaag ggtgacctag tgtatgctgt tcctggtcat ccaagagttg cagagaagac
    58321 tgtaagtata atagagagat tagccaatga aaagcacata gcagtagaaa tattgccttc
    58381 tatgagcttt gtagacgcta tgtttaacta tttggctata gacccatctg agggatttaa
    58441 actggtagat gcttttgaaa tagaaaattc atatatagac ttggatacaa gcatgataat
    58501 aactcaggta tatgataaat ttatagcatc taatgtaaag ttaaaactta tggaacatta
    58561 tgactataat caagaagtat gtatagtaaa tggagcaggt gtcaaagatt tagaaagtaa
    58621 aaagtttata aagctttgtg aattagacag aaatgaaaac ttttttgact atttaactag
    58681 cttatatata cccaaaagtt ctaaaaagat gtataataca gtacatgact tagaaataat
    58741 agttaataca cttagaagtc catctggatg tgaatgggat aaaaaacaaa cacatcaatc
    58801 attaaaaaat tctgttatag aggaagcata tgaactttgt aatgcaattg ataataatga
    58861 tatagatgaa atggtagaag agttaggtga tgttctttta caggttatat tccattgtca
    58921 gataggaaat gaggagggct actttgattt aaaagaagta gtaaatggca tatgtaaaaa
    58981 attaattcat agacatcctc atatatttag tggtgcaaaa ttagatatgt ctaagtttga
    59041 gaaaacttgg gaagaattaa agaaagaaga gaaaggcgaa agtactataa cagatggcct
    59101 tagaaggata ccaaaacatt taccagctct tatgaaggct agtaaagttc aacataaagc
    59161 agcacttgtc ggctttgatt gggacaatgt agaagatgta tttaaaaaaa ttgaagaaga
    59221 atatcaggaa ttacttgacg aacacagggt cgggaatata aaatacataa aggaagagct
    59281 aggcgattta ttattttcga tagtaaatct agctagattt ttagacatag actcaggaga
    59341 agccttgaac tgtactacag aaaaattcat aaatagattt gactttatag aaaaaagtgc
    59401 aatgaacttg aataaaaaat tagaagacat gacacttgaa gagatggatg agttttggaa
    59461 tcaggctaaa aaacaataaa attgtggaag gaaatttgtc aaaaatctag aacttttatc
    59521 acaaagatag aagtctatat tataaacatt tttaggaggt aaatatcgtg aataaagctg
    59581 aattagtatc aaagatggca gaaaaaagtg gattaacaaa gaaggaagca gaagctgcgt
    59641 taaacgcatt tatgagttct gttcaagatg cactagtaaa taatgaaaaa gttcaattag
    59701 ttggatttgg aacatttgag acaagagaaa gagctgctag acaaggaaga aatccaagag
    59761 atccagagca agttatagat ataccagctt ctaaagcacc agttttcaaa gctggaaaag
    59821 gattaaagga tataataaat ggataattag aaatcttgtg aaaaagtgtg gataaatttg
    59881 ccacactttt tctatagaac caaggaaggt gataattatg agattagata aatttttaaa
    59941 agtatctagg attataaaaa gaagaactgt tgctaaagat gcatgtgata aagggattgt
    60001 cactataaat ggaaaagttg ctaaatcttc ttcagaggtg aatattggag atacattaga
    60061 aatacaattt ggagagaaga agatgaagtt taagataaat gaagtaaaag agcatgtatt
    60121 aaaaaatgat gcaaaagaaa tgtacgaaat tttagaataa aattaatagt cctctagtat
    60181 attaatagta gtattattga aatatttact ggggggatat tatggaacag aacataactt
    60241 tgaaagatag atcaaagctg gttatttcgg gagtcgagca catatactct tttaatgaca
    60301 aaagagtaga gctcaaaact tctgtaggcg agatggtaat tgaaggcgaa aacctagata
    60361 tgagcaagct aagtatagac gaaaatataa ttagcataga tggaactata aattctatgg
    60421 tatatgcaaa gcctaaaaag ccacaagaga gtttcttgaa aaaggtattt agatagatga
    60481 taccttttac tcaagatgta agcatttttt atgctactat ttatggtgga atactcatag
    60541 gggtgttgtt tgatttttat agagggctaa gagggaattt taaattcatc aattattttg
    60601 ctataatctt tgatgtattg ttttggtttc tagctacggt tataatattc gtaacaataa
    60661 accttacaga attttttgat ttaagatatt atcattttgt ggctttgttt attggtttta
    60721 ttttatacta taacaccata agtaaaattg ttttatcaat tatcaataaa ataattcgtt
    60781 ttgtgagaaa ttcttttaaa aaagttacac attacatagt cagtttttta aataatttgt
    60841 attacgttat aatctattca ctacacctac tatttgatat tatattttat ataccaaaca
    60901 tatttatagc aacaagaaaa agtataaaaa gaaaatcaaa taaaaaatta aagaacaaga
    60961 aaaaatcaaa acctaagaag aaaaaaaata aaactaaaaa aagggtgtag gaaaaatgaa
    61021 cttaagaaaa aaattttcag gacagattat tgttatcagt ttatttttag gaatatcaat
    61081 ttttagtatg atgacaggat ttgtatttga gtatacaaaa gctaaggaat ataaaaaaga
    61141 aatagcaagt ctaaataaac aattaaaaaa gactgaaata caaataaaca gcttaaagaa
    61201 agatgaaaaa tcatatgaag gagacttaga ggatatagca agaaaaagat tgaatatggt
    61261 aaaaccaaat gaaacagttt atgtagacat aaatcgttga ttaaaacttg ctaataagtt
    61321 tacagatgta ttgattttaa aatttaagat ttaataaaaa agtcattcag ttaaggatgg
    61381 ctttttgttt ttattgagga gggaatttca taatgaaagt aggagctata gatattggga
    61441 caaactcaat gagattattg atagcagatt atagagatgg gaattttata aacagaaaaa
    61501 aatttgttaa tacaactaga attggttatg gtgtggatag taaaggatat ataaaagaag
    61561 atgctatcaa aagaaatata aaagcattaa aagaattttc tgataagtgt aatgatgaaa
    61621 agtgtgaaaa aatttattgt atggggacat ctgctcttag agacagtaaa aatggagatt
    61681 actttgttaa attagctaaa gaagaaactg gaatagatgt tgatatagtt acgggaatag
    61741 aagaatcaaa tttgggcttt aagggtgttt tagaaggaat acaaggtgat gatactatta
    61801 ttgttataga tattggagga ggttcaacag aatttattgt aggtgattca gaaggaatta
    61861 tatttaataa aagtgagaat gtaggtgctc ttaggatgac agagaggttt ttgaagcacg
    61921 atattattga agatgaagag tttgaagcta tgagttcatt tatatatggt gagattgata
    61981 aaacgttaaa tcatataaaa gacagaggat taaaaactct tataggtata ggaggtacga
    62041 ttacatcatt atcagcaatg aatcaagaat tagagattta ctctatggaa aaaatacata
    62101 atagtaaaat acacaaaaaa gaaatagaag aaattctaca aaaattaata aagatgacat
    62161 taagtgataa aaagaactta aaagggctac aagaaaaacg tgcggatatt ataactgctg
    62221 gtgtaaaaat attgaatata ataatggaaa aattagaaat agaagaaata accgtaagtg
    62281 aatacgataa tttggaaggc ttaatatgtc aaaagtcaaa aaaaatgtat taatattttt
    62341 tgatttttaa aaccgattat gacaaaaaaa attactcctc tttgttacaa ttcttaatat
    62401 aaacaaaaga ggaggttttt ttatgcaaag aagtgtagca gttgtgaaga ataagactgt
    62461 aaaaccaaat gtcataaaat taataagcgg atatattgat tttactacgg cggcattcgc
    62521 tgtgatggga tttttactta gtaggtctat tatagtagac tctgtagctc ctttaggaat
    62581 tgcctttttt atatgtgcat caaagattga taagtacaag atacctgtat tcatatcaac
    62641 attattagga atattgttat catctaatga ttttggaaat gtagcaaaat atgctgtgtg
    62701 ccttacaata tttatggcta tgaataaaaa attaaaatta tcagattcaa ttgctaaggt
    62761 tgcatttata ggtgcaataa tactacttcc aatctccatg ggacaagctt tcttttcaaa
    62821 taggtatgta tatggtcttc ttatagcagg agtagaagca ataataatgt ttatatctat
    62881 atatgtgttt tcttatggga taggtttaat ggccaatgtc aacaatagga tgtctgtacg
    62941 gacagaagaa gccatatcaa taagtttact gctaaccttt agcataatgg gaataggaga
    63001 tatatctctg tttggaatat caataaggac cattttatcg accgtattga tattgctgac
    63061 ctcaatagta ggtggagcta ccatgggagc atctagtggt gtaattattg gtgtagcatc
    63121 cattttaaat aatatgacat cagctgttta tatggggata tattcttttt caggattaat
    63181 aagtggagca tttaataaaa taaataaata tttctgtata ctaggatata ttctaagttg
    63241 gacaataata tacctatata cttctggtat tacttctaat atgatgcaat taagagatat
    63301 actattaggt tgtttgatag tactagtatt gccagagcga ttatttaata agattgaaaa
    63361 attaataaaa agtaatgtgg cttcaaatga aatcgtatac gattatatta tgagaagcaa
    63421 aaacctaact aatagcagat tgaacagtat ttataaaact tatgatgacc ttgcagatac
    63481 atttgataag ataagagaaa aagacaaagt gctagaccaa agagacatag ctaatgtaat
    63541 agatatgatt cataatgatg aatgtaaaag ttgtagtatg agaagaatgt gctgggagtc
    63601 aagatttaat catacataca ctatgatata taacattctt gaaaaaattg aggagaaagg
    63661 ggagttaagt ctaaacgata tacctaaaaa ttttagaaag gaatgtatga aaccagagtc
    63721 aatagtgaaa atatcaaatc actattacaa aatgtttgta ttagattatg attggagtgt
    63781 gaagttttca gaaagtagaa agttaatagc aaatcagata agaagtattt caaaatccat
    63841 taaatcctta tctcaagatt tagaaggcga cataatgcta gatatagaaa aggaaaaaaa
    63901 tatatatgaa cagttagaaa gatatgatat aacagttgat aaagtaagtt acttaacaaa
    63961 aagtaacagt gagtttgaaa tatcaataga aaagaaaact tgccatgatg gatgtatgtg
    64021 tgaagataaa attgtaaata taatttcaga cctagtaggt gaaaatatgt ctgttagaaa
    64081 aataggatgt cactgtttag gaggtaaatg caaggcaaca ttcgttaaat ctcaaaaata
    64141 taaggctgtt acagaagttt cagcaatgtc aagggatggg catatccttt gtggagacaa
    64201 ttacacatac atggagataa atgatggtaa atacatgatg gctataagtg atggtatggg
    64261 aaagggtaaa aaagcatatg aagaatcttc tgccactatt gatatactgg aaaaaatgat
    64321 agatgcaaaa attaaagatg agatagtcat tgatactata aacaatatgt tgttgttaaa
    64381 atcttcagaa gagatgtttt caactctgga tttgggaatt ttagatttaa aacgaggttg
    64441 tttagaaact ataaagatgg gagcgtgttc tacttatata aaaagagagg atggagaagt
    64501 tgacttaata tcatcatcat cattacctgt gggtatatta tcagatgtaa aaattgatag
    64561 aaaaaatgta aaagttaagg aaggagacta tgttataatg gtttctgatg gaattgtaga
    64621 tgcaggaaga aataacaatt taggagacaa ttggttaata tacttcttaa agaatataga
    64681 gactacaaat ccaaaggaaa tttcaaattt aatattggat agagcattag agttacaagc
    64741 gttacaaatc gaagatgaca tgactgtttt agttacgaaa atatgtacaa aataaggttt
    64801 acaagattat gtgtataaga tgtggataac ttgtgtataa tatgttaata gacttttgaa
    64861 aaaagtatag ttattaacaa aaataacata taaatcaaca aaatttgttg ataagtatgg
    64921 cagaaatgtt aataaaatgt aaaaaaagaa aaaacaaaag ctattatcaa aagagattca
    64981 tgttgaaata actaaatttc taagtaaaga aaacctgtga atatgttgat tattatgtgg
    65041 ataactatta attcgatatt tatttatata gtatgaataa ttgaataata tatctaaaaa
    65101 aagccatcct attattaagt aaacttattg aaaggatggc tttttatgaa tagaaaattg
    65161 tgcaaagcaa taataccttt atttatttct attttttgca tgttaataat aagtataaaa
    65221 gctgaccaag gatatcaaaa gaataatgac agagcaatta ctgtcatgaa taataatgat
    65281 actgaagatg atgctgaaaa aaaacaagaa atagactatg aaaaaacatg ttggaatttg
    65341 caatctttgt ttaaaagtga tgaccaatgg aaaaaagaac ttaagagttt tgataaagat
    65401 actaaagagt tgaaaaatta cataggtaaa gtaacaaaat cgccaacaca tttgtctttt
    65461 gccttgaaca ttaaagaaaa acttgatata agactaaata aactttctgc ctatgtaaaa
    65521 ttaaaacaag atactaataa aaattcgtat aagtacttag atatgaatga tagtatgagt
    65581 aaatcctatg ggaattatat ggggatttgt tcagatttag agttagaaat actaaaatta
    65641 tcaaacaaag attacaagaa aattatttca aataaaaata taaataggaa atatggtgca
    65701 tatttaagag atataagaag gaataaagta cattatttgg atgataaatc agaagatatt
    65761 ctaagcaaag tatcttcaat aagtagtctt ccaagccaag tatatgaatt atttagaaat
    65821 atggatagaa aaactaattt gacaccagct caatatgcga gtgaattaga gtcatcagat
    65881 agagaaaata gaaaaaaagc ttatcaagat gaacttataa cttacaatga taatataaat
    65941 acaattgcag gtttaattac tggtcaagtt aaaaagaata ttttttattc tcaggaaaga
    66001 ggttatgagt cttctttaga aatgtacctg gaatctgata atgtagatga aaaagtatac
    66061 aataatttga taaggactgt aaatagtaat atggacagtc tacacaaata tatagattta
    66121 agaaaaaaag tattaaaatt agataaggtt cattcatatg atatgtttgt gcctatggtt
    66181 aaggctgttg acaataatat taattatgaa aaggcacaaa gtatagtata ttcagcgttg
    66241 tcacctttag gaaaagaata caatgatgta gtatataaag ctttcaatga aaaatggata
    66301 gatgtttatt cacatgaaaa taaagtaagt ggtggatact gcttatctgt ttatgaaaat
    66361 catccatata tacttttaaa ttataataat tcattaggtt cagtttcgac cttatcacat
    66421 gagcttggac atgctgtata tgaatattta agttctaaga atcagaatta ttttaattca
    66481 aatccgtcta tatttactca cgaagttgca tctacaacga atgaagcatt actttacgag
    66541 atgcttataa aagaagctaa aggcaatgat gaaaaagctt attatataac acagtattta
    66601 gacttgataa aagatactct ttatacacaa actatgtatg ctgaatttga aaaaactata
    66661 cacgagttag tagaaaaagg aaaaagtgta aacgcattag tattaaatga tgtttgggga
    66721 caacttctta aaaaatatta tggacaaagc tatgaattag accaattatc taaggtcgga
    66781 tgggctagaa tcccacattt ttataatagt ttctatgtct ataaatatgc tacaggttgt
    66841 agtgcaggag taagttttgc ccaagacatc ctaaagaatg gttcagataa ctatatgagc
    66901 tttcttaaaa agggaagttc agattatcca ataaacttgt taaaatcaag tggcataaat
    66961 ttaactaata caaaacccat agaaaataca atcaaaaaat ttgatagttt agtagcagaa
    67021 cttgaaaagc tattataaac attattgtaa tccacatggt aaatatatcg aattaatgat
    67081 aaaatatact aaaagtttaa agtcctatca agataggact ttttatttat taattagtgg
    67141 gagatgattc tatgcaagtt aaagttaaaa aggctgtaat accagcagca ggtttaggaa
    67201 ctagattttt gccagctaca aaggcacaac caaaagagat gttaccaata gttgataagc
    67261 caactctaca atacataata gaagaagctg tggcctcagg aatagaggaa atactaataa
    67321 taacaggtag aaataaaaaa tctattgaag accactttga taaatctgta gaattggaac
    67381 ttgatttaga gaaaaaaggt aagaaagaat tgttggaggt agtacaaaac atatctaaca
    67441 tgattaacat acattatata agacaaaaag agccaaaagg gttgggagat gcaatttatt
    67501 gtgcgaggca ttttataggt gatgagccgt ttgcagtaat gttaggggat gatattgtag
    67561 ataatgatgt accttgtcta aaacaactaa cagatgcata tgaggaatat agaactacaa
    67621 tattgggtgt tcaaaaggta aatcaagaag atactaataa atatgggata atagaagcaa
    67681 aaaatataga aggtagagtt tacaaggtaa aagacatggt agaaaagcca gagtcaggaa
    67741 aagctccttc aaatattgct attttaggta gatatataat aactcctgaa atctttgata
    67801 ttcttaagga tttaccacca ggtaaaggtg gagaggtaca acttacagat gctttaaaaa
    67861 tattatctaa gaaagaagct atgtatgcat acaattttga aggcaagaga tatgatgttg
    67921 gggacaagct aggattttta gaagctactg ttgactttgc tctaaagaaa gaagacctta
    67981 aggaagattt tataaaatat ttgaaacatg tatgtagtga atttgataaa aataacaatg
    68041 tgttatacaa taatacagat gaaaaaatag atttaattga agtcaatgaa tctagagaac
    68101 ttgaaattca aaaataatta atgaaaggtg atgtatggtg gcaaaatcaa gtcagaaaag
    68161 aattaataga ataatagctg ttgggattgt gggaatcctc gtaataacga gtataacagc
    68221 tgttttgagt atgattgcaa ctatgtaata agataaatga cagcagttga tatacataaa
    68281 tataaaaacc atatataact tgatgtagtc aaaaacttac aatattttag ttatatatgg
    68341 tttttagaat ttataaatgt aaaaaaaaat ttttataata gttgcatatt ttaaaggaaa
    68401 atattattat aagatataaa tatagtgata aatttataaa aacgtgctaa gattggactt
    68461 gaaatacagt aatatagtag gtaataatgt tttaaatttt atttattgac cataatatat
    68521 aaataatgat attattagac ttaactgttt aaataaaact tttctttttc atgccttcaa
    68581 tttccaaaat aagtatgtat ataaatgaat atatagatga ggaggatttt tttgatttta
    68641 gatgataaag tattagaagg attaggtagt aagaccttag ttgagctacg agagatagct
    68701 aaagaattaa aaataaaatc aattactaca tataagaaaa atgagttaat tgagattata
    68761 aattccaaaa gtaaaaatga ggaaaaagta aacgaagaga ctaaagaaaa aaatgaagat
    68821 attaaagaag acataaagaa tagaaaagaa aatatagagc gtgaaagtat agaaaaagaa
    68881 gttgaatata agagccctac caaatcatac aacaagaaag aaatagatac ccaaaatatt
    68941 tcccaaaacc aagaacatag aaatcaaaga aatgactata ataagacaac gagtgtaaat
    69001 gatagcaata agtcatcaaa tatatctaat agaatggtca gaaataataa taaaaactat
    69061 tatatgccta aacaagttga tgaatctaag atagtagatg aatttaacac atcaaaagag
    69121 gatgaagtag taggtgtact tgaaattctg ccagatggat ttggtttttt aagaggttca
    69181 aattatttgt ctactgaagg agatgtttac gtttcaccat ctcaaataag aagatttaat
    69241 atgaaaacag gagacaagat taagggaata actagacatc caaaaagtgg agagaaattt
    69301 agagcacttt tatatgttca aaaaataaat gatgaaaacc ctgacacagc tatacaaaga
    69361 aatgcgtttg agacattaac accaatattt ccagaagaac gacttacact ggaaactaat
    69421 agaaatgaaa tagctacaag aattatagat ttaatttcac ctataggaaa aggacaaaga
    69481 ggattgatag tagcacctcc aaaagctggg aaaacagttc ttttaaaaag cgttgcaaat
    69541 agtatagcta aaaatcatcc aaatgttgaa cttatagtac tccttataga tgaaagacca
    69601 gaggaagtta ctgatatgaa agaatctatt gaaggagacg ttatatattc cacttttgac
    69661 caagtatcaa gtcatcatgt caaggttgca gagatggtgt taaatagagc tcaaagatta
    69721 gttgaacatg gtaaagatgt agtaatttta ctagatagta taactagatt ggcaagggca
    69781 tataacctta caatatctcc tacaggtaga actttatctg gaggtattga ccctggtgca
    69841 cttcatggac ctaaaaagtt ctttggtgca gcaaggaata ttagacaggg tggttctttg
    69901 acaatattag gaacagcatt ggttgaaact ggttctagga tggatgatgt aatatttgag
    69961 gaatttaaag gtacaggaaa tatggagtta catttagata gaaaattagc agaaaaaaga
    70021 atattccctg caatagatat ttacaagtct ggtacaagaa gagatgattt attgcttgat
    70081 gatgaagaaa agactgctct ttggagatta agaagagaaa tgagtaataa ttcagtaatg
    70141 gaaattacag ataaagtcat tgaacttata aagagaacta aggacaataa agagtttgta
    70201 aaatcaataa agaatttgta aaatcaataa tacaaatgca aatatggatt atataaacta
    70261 atagaaaaat cacttgaatg gcataataag ttgtgctata ataatgtagt tgataatgta
    70321 aaaagaaagt taatataatt aattttttta aataaagaga agaggtgact ataatgcaaa
    70381 aggaaataca accaaaatac aatccagttg aagtgcgttg tgcttgtggg aacacatttg
    70441 ttgctggttc aactaaggac gaaataaaag ttgaaatatg ttcagagtgc catccattct
    70501 atacaggaaa acaaaagaac atagaaaaag gtggaagaat cgacaaattc aagaaaagat
    70561 tcaaaatgga ctaattttta taaaagtgga gttggaggaa gccaactcct attttattac
    70621 aaaaaaacat tcatattcta ctttaaattg tctttttgta ttataataat aaatatgtaa
    70681 aattgagtat tctaaataca ataaaatgag gtgagtggat ggcaaaacaa gctgtaggtg
    70741 ggcaagctgt tattgaaggt gtaatgatgc agtcaaaaga caaaagagtg gtagctgtta
    70801 gaaaaagtga cggagaaata gcactaaaag aagatagaat aaaaagttgg gtaagagata
    70861 agaatataga taagatacct tttgttagag gttcttttgt tatgatagat acaatgattc
    70921 aaggcataaa aagtttaaac ttttcttcag agttttttat ggaagaagct gaagaggata
    70981 aatttgattt atttataaag aaaattttta aagataaggc aaatgatata attataatat
    71041 tttcattggt catagcaatg ttactttctg ctggattatt catttttata cctacattgg
    71101 taggaggagc tttttctaaa gtaatgccta atgattttat gcttaattta atagaaggaa
    71161 tcataaggat agctatatta tttgcatata tagtattgat ttcacgaagt aaggatatag
    71221 aaagagtctt tcaatatcat ggagcagaac ataaatctat atattgctat gaaaatgatt
    71281 tagaacttac agtagagaat gctagaaaat ttaaaagatt acatcctaga tgtggtacaa
    71341 atttcctatt tatagttatg gctgtatcaa taatattgtt tgcatttttt ggttggccaa
    71401 atccaattct tagaatattt atgagaatta tatgtgtgcc tatagtagca ggtttatctt
    71461 atgaggtaat tagagttctt gggaaatatg ataatggatt tactaaaatt attgcatatc
    71521 caggaatgat gttgcaatat tttacaacaa aagagcctga tgatgagcaa ttagaggttg
    71581 ctttggaagc attgaaagca gtagtagatt agagaaaagg atatttgtta tgacgataaa
    71641 agatataatt attaaatatt cagataaact aaaagatata agtgatactc caagattaga
    71701 tacagagtta ttgttacaaa aaacattggg tgttgataga ttatatattc acttaaatct
    71761 gaataaagag ctaactgaag aacaaaaaac aaaatttatg ggttttgcag aagaaagatt
    71821 aaatggaaga ccaatagcat atatagttga aaatagggag tttatgggat tagatttttt
    71881 tgttaaggaa ggcgtattga ttccaagacc agatacagaa actttagtag aagaaataat
    71941 tgaaatatgt agagaaaaaa aagatgtaag tatattagat ataggaactg gttctggagc
    72001 tattacaata agtttagcaa agtacattga aaattctaaa atcatgtctt ttgatatatc
    72061 agagacagca ttagaaatag ctaaaaaaaa tgctattata aatgaagttg gtgaaaaaat
    72121 aaagtatatt aattctgatt tatttacagc aataagtgat agtaacataa aattcgatat
    72181 catagtttca aatccaccat atattaaaaa acaagatata gaaactctgc acaaacaagt
    72241 taaagattat gaaccatata atgctcttga aggtggagaa gatggattag acttttatag
    72301 aagaataaca gaacaaggta agaaatattt aaataagtgt ggaatattag catatgaagt
    72361 tggtcataat caagctgaag atgtaataaa tattatgaaa agtaatggat ataaaaaaat
    72421 atatacaaag aaggatattc aaggcattga tagagttgtt ataggttaca atatatgata
    72481 taatcaacaa ttgatatgtt acatttaatc gaggtgaaag tatgttaaaa aaattagagg
    72541 tattggaaga tacatataaa gacttaagtg aaaaaatagg tgatccggat gtaataaatg
    72601 atcaaaaagt ttggcagaaa tatataaaag aacatgctga cttggaacct attgttatga
    72661 aatacagaga gtataaaagc gttttagata gtataaaaga atcaaaagaa attttacaag
    72721 aagagtcaga tgaagaatta agagaattag ctaaaatgga gttagctgag atggaagaaa
    72781 aagtagcacc tctggaggaa gaaataaaaa tactattatt gcctaaagac cctaatgatg
    72841 ataagaacgt tatagttgaa attagaggtg gagctggagg agatgaagca gctctatttg
    72901 cgggtgattt atttagaatg tactcaaggt atgctgaaag aagaagatgg aaaatagaat
    72961 tattgagtgc aagtgatact ggagttggtg gatataaaga agtatctttt atgataaaag
    73021 gtaaaggtgc ttattcaaga ttaaagtatg aatctggagt tcatagagtt caaagaatac
    73081 catcaactga atctggtgga agaatacaca catcaacttc tactgttgca gtattaccag
    73141 aagttgaaga tgtagaggtt gaaataaatc caaatgattt aagaatagat gttttccgtt
    73201 cttcaggtaa tggaggacaa agtgtcaata ctactgactc tgctgttagg gtaacacata
    73261 tacctacagg tgaagtagta tcttgtcaag atggaaaatc acaattaaaa aataaagagc
    73321 aagctttaaa aatattaaaa gctagacttt acgataaagc attggcagaa caacacaaag
    73381 atatagcagc agaaagaaaa agccaagtcg gaacaggaga caggtcagaa agaataagaa
    73441 catataattt ccctcaaggt agaataagtg accatagaat aaatttaact ttatataagt
    73501 tagatgcatt cttagatgga gatatagatg aaatgataga tgctttaatt actgttgacc
    73561 aaacagaaaa aatgactgca atataagtaa tgttttaaag aagctgtttc ttcctagaaa
    73621 ttattttcta ttttgaaaca gctattttgc attttaggtc atgttatcat attctattgt
    73681 atataattgt tatatacaag tataggaggg ttatatgata ctaaaagtaa caataattgg
    73741 gcttttggca ggtgttatag ggacaggatt aggaggagta atatcagcca tttttaaaag
    73801 agaggtcgat aaatatctaa gtttttttat gggattatct ggtggaataa tgttggctgt
    73861 agtggtgttt gatttaatga aagaatccat ggacaaaatg gggataatca atacagttat
    73921 atttacgttt gttggagctc tcataactat gtacataaaa acaaaattag atgtgtctgg
    73981 aaatatggca tctggatatc ttatattcat aagtatatta ctacataatt taccagaagg
    74041 actagccatt ggttcttctt ttatgtcaac tgaaagttta ggtattacac ttgctatagt
    74101 tataggtcta cataatatac cagaagggtt agctatggca ttaggcttag tttgcaataa
    74161 aatgaaacta agtaaagtta ttttgtttac tgtaatagct ggattaccta tgggtctagg
    74221 aagtttttta ggtgtttatt ttggaggagt atttacttct cttataggag tatttcttgc
    74281 tacagcagga ggtactatga tgtatgttgt attggaagaa atttttccac attcaaaaag
    74341 tgtgtattgt ataattggtt tcttgttagg tacaatgatt gtaaattata tataaaatta
    74401 aaatgaaagc aggcatacaa aagatgaaaa ctattataag taatattgat ataaataata
    74461 ttgattatga ggaaataaaa atacaagcaa aacttcttag agaaggtaaa acagttattt
    74521 ttccaactga gacagtatat gggttgggtg caaatgcatt agatgaaaat gcagtaaaga
    74581 agatttatga agctaaagga agacctagtg acaatccatt gatagtccat atatatgaaa
    74641 aagaagaagt atatgactta gccaaagata taagtgataa agctaaactt gttatagaaa
    74701 agctttggcc aggacctata acaattatat taaataaaaa agatataatt ccatacaaaa
    74761 ctagtggagg gcttgataca gttgcaataa ggatgccttc taatgttatt gccagggcaa
    74821 taataaaaga agctggtata cctattgcag ctccttctgc aaatatctca ggtcgcccat
    74881 ctccaacaaa agcaaaacat gtatatgaag agatgaatgg aagagtggat ggaatagttt
    74941 taggaggaga cagtaatttt ggattggagt caactgtatt ggatttaaca gaagagactc
    75001 ctatgatact gagaccagga agtataacta aagaagtttt agaggaactt cttggagaag
    75061 taaagcttga cccatcatta agtaaaaaag aagataatca aaaagctaaa gctcctggaa
    75121 tgaaatataa acattattct ccaaatgcag atgtatatat aatatctgga aaaagagaaa
    75181 atgtagcaac aaagattaat gatatgataa aatctaatag agacaaaggt ctaaagacag
    75241 gtgtaatgtg tattagtaga aaccgagagt tttatgatgg agaagtaatc gatttaggaa
    75301 actctcttga agaagttgca agtaatctgt ttgatgctct tatagaaatg gacaaaaagg
    75361 gtgttgatgt catatattca gaagagttcc ctaagactgg agttggacaa gcaattatga
    75421 atagactact gaagtcagca ggatacaaag tgataaaggc ttaagaggga gttgtaaaat
    75481 atgaatatac ttattgtgtg tacaggtaat acttgtagaa gtcctatggc tgaggctata
    75541 ctaaggaaag caattaaaga atctggaaga agtattgaag aatattctat atcatcagca
    75601 ggtatatcta cagcaaatgg aatgggtgct tctgaaaatt ctatagaagt actaaaagaa
    75661 atcggtatag acttatcaaa tcatagaagt aaagtaatta ctaaaaaatt aattgatgaa
    75721 tcagatataa tactaacaat gactaaatct cataaagaaa ttttagtaca agcagttcca
    75781 aaatgcaaag aaaaagtgta tacttttaaa gggtttgcaa ataaaaatga ggaagatata
    75841 tctgacccat ttggtggaaa tttggatatt tatagaagca ctatgagaga aataatgtat
    75901 tctgtcaacg aaatagtaaa aaaaatatga aacggaggat aaacaaatga agataggatt
    75961 aggctgtgac catggaggat ataatttaaa aaaagaaata ataagctatt tagaaagtaa
    76021 aggtatagaa tgtgtagatt acggaactaa taatgctaca gattctgttg attatcctgt
    76081 ttatggagaa atagttgcaa attcagttat aaataaagaa gtagattatg gaatattatg
    76141 ttgtggtaca gggataggaa tatctttagc tgctaataag gttcctggga taagatgtgc
    76201 agttgtatca gatgtatttt ctgcaaaaat gtcaaaagca cataatgatg caaatatgtt
    76261 atcattaggc gaaagagttt taggaaaagg tctagcactt gagatagttg aagcatggat
    76321 taatacggat tttgaaggtg atagacatgc tagaagagta aacatgatta aatcaataga
    76381 agaaaaacat aataaataat aaaaattaca gttttatcag gaggaattat caaaatgagc
    76441 aaagtggtag agacaaacca tccattaata caacataaat taactttaat gagagataaa
    76501 aatactggtt ctaaagactt tagagagctt ttaactgaaa ttgcaatgtt aatggggtat
    76561 gaaataacaa aagatatacc attaaaagat gtagaaatag aaactcctat tcaaaaaaca
    76621 tcatctaaag tagttgcagg taaaaaatta gcaataattc caattttaag agcaggtctt
    76681 ggaatggtag atgagcttaa tgccagcagc aaaagttgga catgtaggac tatatagaga
    76741 cccagaaaca ttaaaaccag ttgaatatta ttgtaagctt cctcaagaca taggagaaag
    76801 agatataata gtagttgacc ctatgcttgc aacagggggt tctgctgtag cagctataga
    76861 tttacttaag tctaaaggag ctaaaagtat aaaattagct aatttagtag ctgcaccaga
    76921 aggtatagca gaagtgcaaa aatatcatga tgatgttgat atatatgttg catcagttga
    76981 cgaaagatta aatgaacatg gatatataat tcctggtctt ggtgatgctg gagatagatt
    77041 gtttggaact aaataaaaat aaataactat aaatatttat tagggacttt cttatatagt
    77101 gtatataatt ttatgtaaga aggttctttt ttatatattt tttctcaaaa taggaattat
    77161 tgaattgata aatttctcga attgagaata aaaagttttt accaattaaa aaagattgct
    77221 tattttacaa ggttttatag aatagtagtc tattttaatg tggcatgtta gttgcttacg
    77281 attaagatta taggtattaa gtgtattagt taaattgaga attgaatatt aataatatta
    77341 ttgggagtgg taatacatga agaattgtat agtagtaaga ggggctggag atttagcaac
    77401 agcagttatt cataaattac acaacagtgg ttttaaagta gttgcgttag aaatagaaga
    77461 gccattagct ataagaaggc aaatttcttt ttgtgaggct gtttatgaaa aaaaagtaac
    77521 tgttgaaggt gtagaatgta tattttgcaa tactgaaaaa gaaatagaag aagttttatc
    77581 tcaacataaa gtagccttga ttatagaccc aaaaggagaa aaattatcta aattaaatcc
    77641 aatcgttttg gttgatggaa tactcgctaa gaaaaactta ggtacaacta aagatatggc
    77701 accatttaca atagctttag gtcctggatt ttgtgcagga gaagatgtag atgttgttat
    77761 agagacaatg agaggtcata atctaggaag aataataact aatggtagag cagaaaaaaa
    77821 tacaggagta ccaggagcaa taaaaggttt ttctaaagag agagttatgc attcacagta
    77881 tgatggcata atggaaaatg tatgtaagat aggtgatata gttgaaaagg gagacctact
    77941 ttgctatatt aataattatg aaaaaaaaca tgaagttaga gcaacaatat ctggagtcct
    78001 tagaggttta ttaaaggatg gagcaaaggt aaacaaaaat ttaaaaatac tagacataga
    78061 ccctagaaaa gaagaagtta agaatgcttt tacaatatca gataaagcta gatgtatagc
    78121 tggaggggtt ttagaagcca tactaaacaa tgggatttat ccccaaaatt aatttatatt
    78181 agataaagct attaatattt tattaagatg atataataaa tttaatagat taaagagagc
    78241 atatgacggg tatttaaaat ttaaatggta aaaatgctct ttttttattg gacattcaat
    78301 taacatgtgt atataatata aaaataagta tttatttagg ttgaaatcta ataaatatat
    78361 aataccagta cataagcaaa gaggagaaaa gtaaattatg agaccatcat gggatgaata
    78421 cttcatggaa attgcagaag tagtgaaaaa gcgttcaact tgtattagaa gacaagtagg
    78481 agctgtaatt gtaagagaca aacaaatatt aacaactgga tataatggtt ctccgagaaa
    78541 tcttgaacac tgtgaaaata ttggatgtaa gaggcaggaa ttaaatattc cctcaggaga
    78601 aaggcatgaa ttatgcagag cattacatgc tgaacaaaat gcgataatac aagctgctca
    78661 taatggtatt agtgtagatg gggcaacttt gtatgttact acaagacctt gtgttttgtg
    78721 tgcaaaaatg tgcataaatg caggtatatt gaaaattgtt tatgaaggtg attatccaga
    78781 tgatatgtct acagaattat taaaagaagc aggaatagaa ctcataaaat tttagtggat
    78841 aaaatttata agacaataaa tgtcaaatta tgacactgaa atacaatgat atcaaatgat
    78901 taaaagaaag tatttgaaaa atcatcagat tagtagtaag atatatttta taattaaata
    78961 aatttatgag atagattaat tacatgttat ttattttata ataatgaggg atactattta
    79021 tgagtaaaag aaatacacat acagaaattg caaagttgtt tagtttaata agtcaaatag
    79081 gattgatgat tgtaatatca atattaggat gtactttctt aggaaaattt ttagatagta
    79141 aattgaatac tactccagtt ctgacaataa tatttttatt gttgggtgtt ggaggtgctt
    79201 ttagtggtgt ttataaaact ctaatagtat atacacgaag gaagtgatat attggatata
    79261 aaattactta accaggtaag gtcagtaaca aaaggtatag taatatttga tgtagtttta
    79321 attgtgctaa tgttgataac atcaacatta agtaaaccag tattattagg acttatattt
    79381 ggctctataa tagctatgtt aaattttaga ttattggcga tatcactgga aaaatcagtg
    79441 acatttcctg ctgggaaggc acaagcttat gcatcagcac aatatgctgt tagattattt
    79501 ataatggcag ttgttctaat tgcatcagct acagtaccac atttaaatat aatcggaaca
    79561 gcattgggat tattgagcac aaagtttgtc atattatcaa aaaactttat aaataaatta
    79621 aagaggaagg aggcataagt atgaatcaag cgcattatta tctcatagga aactttaaga
    79681 ttagtgaaac aatactagta agttggggaa taatggcctt tttagcgata gcatcttatt
    79741 ttttgactag aaacttaaaa aaagttccaa ctagtaaagt tcaaatattc ttagaatttg
    79801 cagtaggtgg tcttgctaaa atggttacag atgttatggg taaaaataca gtaaaaagaa
    79861 tgccatatat gataccatac ataggaagct tgtttttatt tttcgcatgt tcaaatttaa
    79921 gcccattact tggattaagg tcaccaacaa ccgacttaga cacaactgct gcatgggcaa
    79981 tgattacatt ttttatgatt tattttgcag gagttaaatt taaggggtta tcatacttta
    80041 aagaattggc tcaaccactt gccataatgt taccaatcaa tattataggt gagttagcta
    80101 gaccaatatc attaagtttc cgtccatttg ggaatatttt aggtggaaca ataataatgg
    80161 gtctgtttta tcaactttta ggttttatat ctagtttaat accaggatta tcaataccaa
    80221 ttggagaaat attaatacca gtcccattac acttgtactt tgacttattt gcaggattgt
    80281 tacaagcata tatatttata atgttaacaa tggtatttat atcaagtgca ggagagttag
    80341 attaagaaat caacttatat taagataaaa ataaaataat ttaaaaaatt aaagttttaa
    80401 ggaggaaata attatggaaa cagcaatagt agcggcagca tcagcaatag gagcagggat
    80461 agcagttgca acaggtatag gtgcaggtat aggtcaaggt atagcagcag ctaaagctgc
    80521 agaagcagta ggaaaccagc cagaagctaa aggtgatata acatcaactt tattactagg
    80581 agttgctata gcagagtctt cagcaatata tggtttggtt atatcaataa tacttctatt
    80641 cgtaaatcca ttctttaaat acttaggaat gtagatttag tccttaaata ttttgagata
    80701 ggtttatagg taaatcatct caaacttata atcatgagat gaactttatc atctcgtgat
    80761 tataagtagt tatgatttat ggaaaggagg ataattatgg aaaaagcact agtaggtata
    80821 acgtgggaat ttgtgttcca aattgttaat acttttataa tatttttact tctgagaaag
    80881 cttttattca agccagtatt aaatataatt gaatcaagag aaaatgatat taaaagtgat
    80941 ttggcagaag gcgaaaaagc aaaaaatgaa ggtttagctc tgaaaaaaga atatgagtca
    81001 aaaatcaatt ttgccaaaga tgaaggtcaa gaaatcataa aacaagcaac tataagagca
    81061 gagcagaaat cagatgatat agtaaatact gcaaagaaag atgctcttga tataaaagaa
    81121 aaagcaaaca aagatataga acaagaaaga caaaaggtta taaatgaaat caaaaatgat
    81181 atatctaaca tagcactact tgcagcatct aaagttattg aaaaagattt agataaatct
    81241 aaacatgaag aattgataga aaactttata aaagaggtag gggaagctaa atgataaatg
    81301 taatagcaaa tagatatgca gaagccctat ttcaattagg agaagaagaa aattcaactg
    81361 atgtcttatt caaagaacta gaaaaagtag tagatatgat gactaaagtt agtaaagatt
    81421 tctacaaagt tttaaaatca ccattagttt caaaatcaga aaagaaaaac ttggtagaaa
    81481 ttatttttag taaagaagta agttctaaca taaaaaactt tttaaaagtt ttagtagata
    81541 aagatagaat atcatattta gaagatatcg aattagctta taaagaatta ttaaataaga
    81601 aaaacaatgt aattgatgga gtagcaataa gtgctattcc aatgagtgaa acagatatta
    81661 aagaacttga agtcaaactt tcaaataaat acaacaaaaa tgttactata gaaaatgttg
    81721 ttgacaagac tatactaggg ggagttctag ttagaattgg aaatgaacaa atagatggca
    81781 ctgtgaaaac tcgtcttgat aagatgaaag aaaagctatc tgaagtaata tcttaagaat
    81841 ggcggtgaac ccatgaactt aaaacctgaa gaaataagtt ctataattaa acagcaaata
    81901 aaaaattatg agaataaagt tgagttgaca gatacaggta gtgttttaac agttggggat
    81961 ggtatagcga gtgtatatgg attagaaaaa gctatgtctg gtgagttgct agagttccca
    82021 ggtgaaatat atggtatggc acttaacttg gaagaagaag tagttggagc tgttatcctt
    82081 ggagatgaca gtgaaataaa agaaggcgat atagttaaga gaactggaag aatagttgaa
    82141 gttccagttg gagaagcttt aataggtaga gttgtaaact cactaggtca gccaatagat
    82201 ggaaaaggac ctatagcgta cacaaaaact agaccagttg aatctgaggc acctggtata
    82261 atagatagaa ggtctgttta tgaaccatta caaacaggaa tcaaatcaat agattcaatg
    82321 ataccaattg gtagaggtca aagagagtta ataataggtg acagacaaac tggtaaaaca
    82381 tctatagtta ttgacactat actaaatcaa aaaggaaaag atgttatctg tatatatgta
    82441 gcaattggac aaaaacgttc tactatagct caattagtta gctctttaga aaaaggtgga
    82501 gctttggatt atacaatagt agtttcagca acagcatctg aatcagcacc acttcaatat
    82561 atagcaccat atgctggagc agctatgggt gaagaattta tgtacaatgg gaaacatgta
    82621 cttatagtgt atgatgattt aagtaaacaa gctgttgcat atagagaaat gtccttgtta
    82681 cttagaagac caccaggacg tgaggcatat cctggagatg tattctattt acattcaaga
    82741 ttacttgaaa gagcagctaa gttatctgat gaattgggtg gaggttcaat gactgccttg
    82801 cctataatag aaactcaagc tggtgacgtt tctgcatata taccaacaaa tgttatatct
    82861 ataacagatg gtcaaatata cttacaacca gagttattct attcaggtgt aagaccagca
    82921 gttgaccctg gtatatcagt atcaagggtt ggtggttctg cgcaaattaa agcaatgaaa
    82981 aaagttgcag gaacattaaa acttgcatat tcacaatata gagaacttgc agcattctca
    83041 cagtttggtt ctgacttaga tgaagatact aaaaagagac ttgctcaagg tgaaagaatc
    83101 gttgagatat taaaacaagg tgagcatcaa ccaataaaag ttgaaaatca agttatgata
    83161 atatatgctg ttataaataa tcatttagag gatattccga tagataatat agctagattt
    83221 gaatcagaat tgtatgcatt tgtagataat aattatccgg aaatatcaag aaaaatatta
    83281 ggtggagaag acttcactca tgatttaaca gatgcaataa atgaatttaa agaaaagttt
    83341 gttgttgaag tataatcctt tttaaaaaag gaggtaaatt aattggcagg agctggaatc
    83401 aaagcaatca aaacacgtat gggaactgtt gaaagtacaa agcaaataac taaagcaatg
    83461 gaattagttg catcttctaa gcttagaaaa gcaaaagaaa aggctgaaga ttcaagagaa
    83521 tattttaata ctttatacaa tacagtaaaa gatattgccc aaacaacacg tggaattaga
    83581 aatgaatttt taaaagaaag agaagtaaaa aataaatgct atgtagtagt agctggagac
    83641 agaggacttg caggtggata caattctaat gtattaaagg aatctgtctc tcatatgaaa
    83701 ggtaaaaagg aaacagtgat tactgttgga aagaaagcac atgaattttt ttctaaaaga
    83761 aactacaata tagcaaaaga tataaatagt gttgaagctt gtggatatga agatgcgaca
    83821 gaaatttcac aaactattat tgacctgtat aaaaaaggtg aagtagatga agtttatatt
    83881 gcttatacaa aatttaaatc tgctttatca caagaagttg aaattttgaa attgcttcca
    83941 ttagtctttg aaaaagatac agacgaacaa ggaatggcag taaaagaaga aaaacaaaat
    84001 agatcaaaag tacaatatat accatcagca gaagcagttt taagttatat tgtacctcag
    84061 tttatatcag gtacagtata tggtggaatt ttggaatctt ttgcatcaga gcaaggtgct
    84121 agaagaactg caatggaatc agccacagac aatgcgaatg aaatgctatc taatttagag
    84181 ttaagttata acagagcaag acagtcagct gtaactcaag aaataacaga gatagttggt
    84241 ggagttgaag ctctaaaata gggaggttag gaaatggcaa atgtaggtaa agtagtacag
    84301 attgtaggag ctgtactaga tgttaagttt gatagtgaac aaagcctacc taacttatta
    84361 aatgcgttag taataaagtt aggagataaa gaaatagttg cagaagttgc tcaacatata
    84421 ggtgatgata ctgtaagatg tatagctatg agtgcaacag acggacttgt aagaggtatg
    84481 gaagttgtag atacaggagg gccaataagt gttcctgttg gagatgaaac tttaggtaga
    84541 atattcaatg ttcttggaaa accagttgat gggaaaccag ctccaaaatc tgcacctaaa
    84601 ttacctatac atagaccagc accggcgtat gatgaactag aaactacagc agagatacta
    84661 gaaactggta ttaaggtagt tgacttacta gctccatatc taaaaggtgg aaaaataggt
    84721 ctatttggag gagcaggagt aggaaagaca gttctaatac aagagcttat aaacaatatt
    84781 gctaagcaac atggtggtat ttctgtattt tcaggagtag gagaaagaac aagagaaggt
    84841 aacgaccttt atggcgaaat gagtgagtct ggagttataa ataaaacagc tctagtattt
    84901 ggtcaaatga atgaaccacc tggagcgaga atgagagttg ctttaactgg acttacaatg
    84961 gcagaacatt ttagagatga gcaaggacaa gacgttttac ttttcgttga taatatattc
    85021 cgtttcacac aagctggttc agaagtttca gcacttctag gacgtatgcc atcagctgtt
    85081 ggttatcagc caacattagc tactgaaatg ggtgcacttc aagagagaat aacatcaact
    85141 aagaaaggtt caataacatc tgttcaagca gtatatgtac cagcagatga cttaactgac
    85201 ccagcaccag ctacaacatt ctctcactta gatgcaaaaa cagttttatc aagacaaata
    85261 tcatcactgg gtatatatcc agcagttgac cctcttgaat ctacatcaag gattcttgac
    85321 cctagtatag taggaaaaga acattatgaa gtagctagag gtgtgcaatc aatacttcaa
    85381 agatataaag aacttcaaga tataattgct atacttggta tggatgaatt atctgatgaa
    85441 gataagttaa tagttgcacg tgctagaaag atacaaagat tcttatctca atcattcaca
    85501 gttgctgagc aatttacagg aaatccaggt caatatgttc ctgttaaaga gactgtaaga
    85561 ggatttaaag aaattcttga agggaaacat gatgacttac cagagtcagc attcttattt
    85621 gtaggaacaa tagaagacgc tgttagaaaa gcgaagggaa gtatgtagtc atggccagtg
    85681 aattttcatt gaaagttgta actccaagta atacttttta tgatggagat gttgaaatga
    85741 tagtagttag aactacaaaa ggagacaaag gggtgttgaa aggtcatata ccatttgttt
    85801 caggtatacc tgtaggaact ttaaagataa aaaaagaggg aagttttaaa gaggcgaaaa
    85861 tagcagaagg attcattaat gtaactcaag ataaaactgt catattgaca gaatctgctg
    85921 agtggattta ataaattaat ttagagtata aaaagtcatt ttgaccaaaa aaaacttttg
    85981 ggtaaaatgg cttttttgcg ttttggtgtt aataaaataa cgataaaatt gtaagttttt
    86041 agtgataata aattcacaaa atgtttaaat ttactgccaa attatgttgt aattaataag
    86101 ataaagaaga tttagatagc ttttatgtaa gtgaaaaagt cttcatataa gaaatacata
    86161 taaaattttt ataaaattta aaaaatttgc ttagttgtgt agtataataa ataatataat
    86221 agatttgtat ataatattca ttacaaataa ttttaaaagt tacagtttta ttataatgat
    86281 tattaaatta agataagtaa cataaactaa ataataatgt gtattatcga tagtaaattt
    86341 ataaattcat tattaattat tgaaagaagt attataaatt ttctggagga acaatgaata
    86401 tatttgatat tggcgtagat ataattgaaa ttgatagaat aagaaaggct gtagacaaaa
    86461 ataataggtt tttggagaag atatttacag atagagaaat agagtatttt aattctaaga
    86521 attttaaagc agaaagtata gcaggtaatt tcgcagccaa ggaagctata agtaaatcta
    86581 taggtacagg aattagagtg tttaatttta aagatataga agttctcaga aatgaaatgg
    86641 gaaaaccaat agtaaaaact tataataatc tagcaaaaat gtgcatagat tataatgttt
    86701 tagaaataaa agtttcaata tcacattcaa aagattatgc tatagcaaat gcgataacca
    86761 taattaagga ctaaggagtg attacattat gatggataaa acagcaaaag aaataatgac
    86821 aacagatgta atagtagcaa aacaagatga tagtatagca gatgtagcta atatgctaat
    86881 tgcagaaaaa ataggaggtc tgccagttgt agattcagag aatagagttg ttggaataat
    86941 ttctgaaaca gatattctta aaaaagaaaa atatatagaa gcacctctct atataaatct
    87001 attacaagga ttgattttct tagatgactt aaaaaaagtt gaaaaagata taaaacaagt
    87061 agctgcttat aaggttggag aacttatgtc taaagatata ataaaggttc atgaagatga
    87121 taagtttgat gatgtagcta atgtaatgat taaaaaatca ataaacagag ttcctgtagt
    87181 agatgatgac aacaaactta aaggtataat ttgtagatat gatataataa aagctttata
    87241 caatgaataa actgaagtag gaggtgtgat gtgagaaaaa agtggaccat agtatgtatt
    87301 atgttcttgg cactggttat aattgtaata ggatgccaaa aacgacagtc cacaaaagaa
    87361 gaagtataca aagattttca aaagcagatt tctgatatga attattacag ttgtaaagct
    87421 gaagtagaag tagttggaaa taaaagtcca cacaattatg ttttaattca tacttataaa
    87481 aaaaccgata actataaatt agaagtaatt tccccaaaac atttaaaagg gaaaagtata
    87541 gaatatcaag gtgataaaat attagttaaa aatccaaaga ttagtgatgt agtggagtta
    87601 cctaatacag gaaaaaataa tcaatatctt tttgtaggag actttataaa aaactatctt
    87661 caaaatgagg agatgaaagt aaagttatcg aaaggacatt tggttttaga gacttttatt
    87721 cctggggata ataaatattt taacaagcaa gtattatata taaatgctga cacaaaaaat
    87781 cctgaaaaaa tggaagtgtt agataaagag ggagtgccaa gatttacagt aaaatacaaa
    87841 gattttgaat acagaaacta agggggacta aagacatgca aaaaataaca gtgcctacat
    87901 gggcagagat aaatctagat aacttaagat ttaacttaaa taatattaaa aatttattag
    87961 aagaagatat taagatttgt ggagtaataa aagctgatgc atatggacat ggtgcagtag
    88021 aagttgcaaa attgctagaa aaagaaaaag tagattactt agcagtagca agaactgctg
    88081 aaggaattga acttagacaa aatggcataa cacttcctat tttgaacttg ggatatactc
    88141 cagacgaagc ttttgaagat tctataaaaa ataaaataac tatgacagtt tattctttag
    88201 aaacagcaca aaagataaat gaaattgcaa aatctttagg agaaaaagcc tgtgttcatg
    88261 ttaaaataga ctcagggatg actagaatag gtttccaacc taatgaggag tcagtacagg
    88321 aaataataga attaaataaa ttagaatata tagatttaga aggtatgttt actcattttg
    88381 ctacagctga tgaagtaagt aaagagtaca cttataaaca agctaataat tataaattta
    88441 tgtctgataa attagatgag gctggtgtaa aaatagctat aaaacatgta tcaaacagtg
    88501 cagctattat ggattgccct gatttaagat taaatatggt aagagcagga ataatattat
    88561 atggtcatta tccatctgat gatgtattta aagatagatt agaattaaga ccagccatga
    88621 aattaaaatc aaaaatcgga catataaaac aagttgaacc aggtgtagga ataagttatg
    88681 gactaaaata cacaactaca ggtaaagaaa caatagctac agttccaata ggatacgcag
    88741 atggatttac tagaatccaa aaaaatccaa aggttcttat taagggagaa gtgtttgatg
    88801 tagttggtag aatatgtatg gatcaaataa tggttagaat tgacaaagat atagacataa
    88861 aagttggaga tgaggttata ctatttggag aaggcgaagt tacagctgag cgtatagcta
    88921 aagacttagg aactataaac tatgaagtgt tatgtatgat atcaagaaga gttgaccgtg
    88981 tttatatgga aaataatgag cttgtacaaa taaacagtta tttgctaaaa taaaaccatg
    89041 atattataat ctgggaggcg attttgtgta cgataagagt aaagaaaaaa tagaagttac
    89101 tttacctgac tctctgattt ctgaagttga tagtatagtt cagatggaga acagtaacag
    89161 agaagatttt gcaaaagctg cttttcagtt ctatataact cagaaaaaga aaattcatat
    89221 taaagaatct atgaaaacgg gttatagaga aatgggtcaa attaatctgt cactagctga
    89281 attaggtatg acagttgaag aagtatcttc tgatgataaa aatgaaggga agattgccca
    89341 aggtgagtac taattgtgaa ataaagcgtg gtgatttata ttacgctgat ttaagtccag
    89401 ttgttggttc agagcaggga ggcgttagac ctgttctgat aatacaaaat gatgtaggta
    89461 ataaatatag tcctacagtt atagtatcag ctataacatc tcagattaat aaagccaaat
    89521 tacctactca tgtagagata agttccaatg aatatgggct taataaagac tcagtaattc
    89581 ttttagagca aattagaact atcgataaaa agagactgag ggaaaaaatt ggttgtctag
    89641 atgaaaatat gatgataaaa gtagatgatg gacttcaaat aagtttagga ttgtttactt
    89701 tttaaagagg gatttgtctt ttattagaca atcccttttt tcttttaaat atctcttaag
    89761 gtttaatttt aatgtactat gttaataaaa ttaaaaataa cgcaaaaaaa tagcataaaa
    89821 gtgatataat aatatggaat tgatataaaa ttacgaactc aagggaggta attgcatgag
    89881 agaccataaa ggattaaatg agattgcgcg tatcataaga agagatatag tttcaatgat
    89941 acatagagcc aaatctggac atccaggagg gtcattatca gtagttgaaa tacttactgc
    90001 gttatacttt gatgaaatga atgtggattc ttcaaatcct aaaatggagg atagagatag
    90061 atttgtatta tcaaaaggac atgctgcacc agcattatat gctacattgg ctgaaaaagg
    90121 ctattttgat aaggaagaac tgaatggatt aaggaagata ggaaggatgt tacaaggtca
    90181 tccagacatg aaaggcacgc caggtgtgga aatatctacg ggttctttag gtcaaggttt
    90241 ttcagttgca tgtggtatgg ctatggcatc aaagttggat aatgctccgt ggaatgtgta
    90301 tactttgctt ggtgatggtg aggttcaaga aggaattgtt tgggaagctg ctatgagtgc
    90361 tgcacattat aaacttgata atttaattgc ttttttagat aataatggac ttcaaataga
    90421 tggagatata gaaagcgtaa tgagtttagg ttcaatagtt gataaattta aagcttttgg
    90481 ttggaatgta attgagatag atggacatga ttttgaccaa atatttgcgg ctcttgatat
    90541 agctaaatca acagttaaaa aacctacaat gatagttgca aaaactataa aaggcaaagg
    90601 aatatctttt atggaaaatc aagcaggatg gcatgggaca gctccaagtg atgaggagct
    90661 agaaaaagcc ttgcttgaat taggaggtgc tgacaatgag taaaatggcg acgagagaag
    90721 catatggtaa agcattagta aaattaggtc aaataaatga caatgttgta gtattagatg
    90781 cagatttatc aaagtctaca aaaacacatg atttttacaa gtcatttcca gatagatttt
    90841 ttaatatggg tatagctgaa caaaatttaa taggcgctgc ttgtggatta tcaactgctg
    90901 gtaaaatacc ttttgcaagt acttttgcta tgtttgctac gggaagggct tttgagatta
    90961 taagaaattc agtttgttat ccaaagctaa atgtaaaaat atgtgctact catgcaggtc
    91021 ttactgttgg agaggatgga gcatctcatg aaagtgtgga agatattgct ataatgagag
    91081 ctataccaaa tatgacagtt cttgttccag ctgatggagt tgaaacagaa aaaattattt
    91141 ttgaaatagc taagtataat ggacctgttt atgttagatt agggagaagt tcagtaccag
    91201 ttttatttga tgaagattat aaatttgaaa taggaaaagg tacagtctta agagaaggaa
    91261 aggatgtatc aattatagct tgtggaatta tggtaaatga agctctatta gcacaagaaa
    91321 agttgcaaga agaaggtata agtgctagag ttataaacat gtcctcgata aaacctatag
    91381 acaaagattt aatattagaa tcagcaaaag aaacgaatgc tattgtaact gtagaagaac
    91441 atagcataat tgggggatta ggttctgctg taagtgaggt agtaggagag tcttgtccaa
    91501 ccattgtaaa gaaagttgga attaaagata catttggaga atctggtact ccaaatgaat
    91561 tgttaaaaaa atatgaatta acttgtgatg acatagtaaa gactgttaaa gaagctatta
    91621 ttgcaaaaag aatgtaagag atataaatta ttcatgtttg ttaataatat aatatattta
    91681 aaagagaggt ataaagtgtt atattaattt atatctctct tttttttata tgatatcaat
    91741 atatcaaaaa tgtaataaaa tattcaaatt tttacaaaaa tagagaaaat attcaaatat
    91801 atattgacta ttcagaaaaa tatgactaat atataattta tagagaaact aattttatat
    91861 ataatgacta cttagataaa agaatctaaa aaaattatga gaggaggagt agggtataaa
    91921 atcagattat aagttttaag ttattatact aaaaagctat aaaacagtta tcatgtattt
    91981 tatgttaaag gaaattgtag gtagtttatc gaattgttta atcagaagaa aaaatttcac
    92041 atggggaggt aactgagata tgtcagaaaa agtaaatgtt aaaacagtca tcagtttcgc
    92101 aggtgcgtat gtagcaacag taatcggttc tggatttgca acaggacagg aaataatgca
    92161 attcttctct ttttatggtt ttgcaggtat tattggtggg ataatttcaa tggtattatt
    92221 ctcatggatg ggtgcttcag ttatgtcaaa aggtaaagag cttcaactta aagaacctat
    92281 caaaatttat cgtgtttatt gtggtaagta tttaggaata ttctttgaat ggtttggacc
    92341 tttattctta tttggtgttt tcgtagtaat gatttcagga gcaggagcaa ctttaactga
    92401 atactatgga ttaaatccat ttgtaggtag agtaggtatg gcagtagtag cattattaac
    92461 tgtttcacta ggtcttgata aattatcaaa gatactaggt ggaatagggc ctataataat
    92521 aatctttaca cttttagttg gtggtataag tttagctaaa aacataggta atataggaga
    92581 agctgcacaa gttcttagca ctgtaaagat agctaaacca gttccaaatg cctatctatc
    92641 tggtgtaata tatactactt ataacacaat tgttgttatg gcattcttaa ctggattagg
    92701 agcaagtgct gctaacaaaa aagaagctat ttgtggtggt atattaggtg gagtagcact
    92761 tatggctgca gctataatga tgcacttagc tattctttct gatataggaa acttatattc
    92821 aaaagcaata ccatcattat tcttagcaga taagatttca ccagtaattg gagttttatt
    92881 ctcaataatt cttatattag gtatatatac aacagctgta cctttattat ggtcagtaac
    92941 taatagattt gtagatgata aacatcctaa gtttaaatta ataactttaa tagcagctat
    93001 attaggtctt ataggtggct tcctaccatt tgataagctg gttggtattt tatatccata
    93061 tactggatat atgggcgtca taatactggt ttgtgttctt tatagacaga ttacaaaaac
    93121 atctggatat caagaaggaa tcagtgacaa ataagtattt tttaatattg taaactcaag
    93181 agctatatga aaacaatgaa aatgttttca tatagctctt tttatttttt agctcgttta
    93241 ttatgaaata gaaaaaacat gttttttagt tacattacat atatttataa ttatgtataa
    93301 atatatacta atcaataatt tagagtctaa gataagttta taaatcatat atttagaata
    93361 tatgggagga gtgataagat tgaatgtaaa gtttaatatt aaaggtataa tttatggagt
    93421 tatagctctt gtattcgtta tagggggatt tatattcata ccaagtatgt ttgtagagaa
    93481 atctaaaccc atagattata cagtattaca aagaaattca ataccagaaa agatattaga
    93541 tgtgatggat aagtatacaa atgaagaaag agcattagcg gctaaaatcg ataacaaaat
    93601 atacattata gtgactagag gaaataataa atatggtata gaaatggaca aaatagaaag
    93661 tgtggttgag gaaggaaagg atgttttgag agtcaagata aagtataaag ataaggaaga
    93721 ttcttttcca tacatagttg ttgaaacaaa tatgagtgaa cttccagata gaatagaatt
    93781 aaatgcgacg aaataagaag gtattttata attaaataac tgcatattgt acaataaagt
    93841 catggttttt attaatgtaa gtaaattgtg tatggttctt attgttgtaa aagccatgac
    93901 ttaaaatgct tataaagtaa gatattaaca gtagtattta ttactacatt aaatggggtc
    93961 tggaaatact taatattcta actatttgga gtgataattc tagtttcagt aactatgtag
    94021 tctaattgtg catcatgagt ttcttttgga atagaatcga atatctggaa gtcaaatgct
    94081 atgccgatag ttatagcatc ttttcttaag ttttctaaaa atctatcata aaatcctcca
    94141 ccatatccta atctatagca atgtatatca tatgctacag ctggtacaat tacaacatct
    94201 aaggccttaa tatcaattgt aggtgatttt tcgttaggtt ctcttattcc atatgctcca
    94261 attctcaatc cctcttttaa atctgttatt tgagtaggga ttaatgtatg attttctttt
    94321 attgtgatgg gacttgatac tattttcttt agagacaaaa gttttttgat taaattatct
    94381 gtttgaactt cattgttaaa atttagataa agcattatat tagttgcatt tcttatatct
    94441 tccatttgaa gtaatttttc agttattaaa tttgaattac taagtacaaa gtttgcactc
    94501 ttattttttc ttgattcaat aacttttttt ctaaattctt ttttcataaa ataattcctc
    94561 ccttaatatg ttataatgtg tacagcaatt gtatttaata taaattttag tataatttat
    94621 tgtaataaag caatatattt gggtaaatgt aataaaaata acagctagtc atataataat
    94681 aatagtttat gtaaaaggag atgtatcttg tgatttcaaa gaagaaagct atttttttag
    94741 gggtgatttt agtaattata acagctatgg ttacatcagc atttcagttg acattgggga
    94801 ataaagttgt aatatcgaaa gaactctatg aagactataa aaaatatgat aagttgttag
    94861 gactagaatc tatcataaaa caagattttt ataaaaaagt atcagatact gatttggtaa
    94921 atggagcatc aaaaggtcta tttctaggaa caaatgataa gtattctggt tattatacta
    94981 aagatgaaat ggagaatcta attaatgata gtgaaggttc ttatgttggt gtaggtatgt
    95041 atataggggc atcaaaagat ggtggcttag tagtagttcc catgaaagat tctccagcag
    95101 agaaagcagg tgtaaaatca ggggataaat tagtaaaagt caatggaaaa tctgtctcat
    95161 ataaaaattc agatgaagct gttcgtatga tgaagggtaa aaaagggaaa atagttgaac
    95221 tgactatatt aagagaagat aaacaattga actttaaagt aaaaacagac cagataattg
    95281 agaagagtat agaaagtaaa gtaattgata atgatttagg atatatagaa attacccaat
    95341 ttatatcaag tacatatact gactttgata aagctttaaa agaattaaaa gcaaaaaata
    95401 tcaagggatt agtaatagac cttagaaata atcctggtgg aatgctagat atatgtaaag
    95461 aagttgctga tgagttaatt ggtgaaggaa ctatagtata tacaaaagat aataagggaa
    95521 atactgagta cttgaaatct gataaagaaa aattgggact tccaatagta gtgttaacta
    95581 atggagaaag tgcttctgct gctgaaatat taacagctgc aatcgttgat aataaagaag
    95641 gtatttctgt agggactaca acttttggta aagggttggt acaatcagtt gtaagattga
    95701 aggatggaac aggatacaag ctaactactg ctcaatattt tacacctaat ggggattata
    95761 tcaatgaaaa aggtataaag cctactattg aagagaaaga tgaaaataaa cagttagatg
    95821 tagcaactaa gtggcttaga gaacagattg ataaataaaa tttaattttt ataaatttat
    95881 attgtaaaat aaagaacctt aataaaagga gtgtctcaaa attaactttt tagggtcttt
    95941 aaaataaagt gtgtattctt ctaaaaagta gtgataattg aaatattaaa tatcactata
    96001 taaaggaagg tgcacacttt ttatgcttaa taaaaacaaa atattaaaaa acttattgaa
    96061 gaatatgatg ttaaaacaac tacagatatt caagatatgc gaaaagattt atttgcaagt
    96121 acaattcatc aaatgttaga agtatagctt gatgaccatt taggttatga tagatatgac
    96181 aataagaata aaaatactaa aaactctaga aagggatata gaaataaaaa tattaaatca
    96241 gattttggag aaataacttt aaatattcca agagaccgaa atggagattt tgaattaaag
    96301 gtaattagaa attatgaaaa tgatatatct cattctctaa tagataaaat tactgataga
    96361 gttatacctt tagctcattt aagtatttat tttgaagaaa aaatttaaaa tctaagttaa
    96421 taaagaaata tttcaaaaaa attaagaaat tttcttaaag gagtaataat ttttgcaaaa
    96481 ataaaaaaac atcaaagtaa ggctatgatt tttaaaggca tagccttact ttgatgttta
    96541 attattactt aaagaataaa tttttatttg tagtgaaaac tccgtagatt ctattaacat
    96601 gtatacagca ggtttttgct ttaatttatt tagagtcacg caatatctat atcatgggta
    96661 ccaccatagt tgtataggaa gttatttcac cgaatccttt tcttacttta tcgtatatta
    96721 tattgttgta ttattcttaa cattagtcta aagtactttc tataatttac taaattcagt
    96781 ttgcaagtta ttggcttgtt ctttaaggac tttaattaaa tattcttctc ctttgtgcat
    96841 taatcgattg ctaggaccag taatactaat agcacatatt aaatcattat tgcaatcaaa
    96901 aataggaact gcataacaag acaatccata ttcatactct tcattgtcta ttgataaatt
    96961 tagttccagt attctttttt tagctaacag aaactcgtta tactctgtga ttgtatttac
    97021 agtacgcttt tctaagttat taaagtaatc ttgaagaaat tcttcggatt cttgacttag
    97081 gaataatttc cccattcctg aacaatacaa aggactaaca ggtataaggg ttgtttgtaa
    97141 ttgataaaac tctccttcta ttgattttac aataataact tcattttgat aacggatacc
    97201 tagatttacg gattctccag tttctttgct gattttttgc aaatagggtt ctgctacaga
    97261 aattaattta ttttcttggc ttgttccctt cgcataagat aataaacgat aatcaagagt
    97321 atagtcgctg ttttctaatt gctttataac atgaatctct tcaagtgttt taactatacg
    97381 aaagacacta gtcttaggaa tagataatat ttctgaaatt ttagcaatac ctatacttcc
    97441 tttttcatta ataacatcaa ttattctaaa actatcaact atgttcttga taataggact
    97501 cttcttctcc ataattgccc accacctttc ttttaaattc taagtctaat tagttaaaat
    97561 ggcaagacgt attttcaaac ttcatatatg taaagctcac taattattag tattttttca
    97621 ctaattttag ttgtttcttt ataaaaaaga gataaaaaca aaaaaacttt gttatttatt
    97681 attaaaggta ttgactatat gattttataa tagtattata attttggaac gtgttccgaa
    97741 attataaaag ggggtaataa aatgaaagtt agtattattg gtgcaggtgc tgtaggtgct
    97801 acaactgctt ttacacttgc taaaacaagt tttgtagatg aaattgcaat tgttgatatt
    97861 gatcaaaacc gtgcaaaagg aaatgcatta gatattcttc atggattatc tttaatgcat
    97921 gaaacaagaa ttgtttcagg tgattatgat tgtgcaatta actctgatgt tattgtaatt
    97981 actgtaggag tacctgaaaa agttggcgaa tcacgtttgg ttccattaca aaaaaatgta
    98041 aagatacttc aggatattat accaaagatc acaagtacga gtcctaacgg attattattg
    98101 gttgtaagta acccagtcga catcataagt tacttttctc aaaaaatttc agggtgggaa
    98161 gcaaaacgtg ttattggttt aggtacaacc cttgattccg ctcgtttaaa ttatttaatc
    98221 gctcgtgatt taaaaatttc acaaactgat attcaaggtt tagtaattgg tgaacatggt
    98281 gactctcaag ttgttgcttg gagtcaaaca agtgttaaag gaacaccttt cttggattat
    98341 gttaaatcta ataacatctc gttacaagaa gattactgta ataatttggc tcaagaagtt
    98401 aaagatactg cgtttgatgt atgggatatg aaaggaccaa attgttactg tgttgccttg
    98461 gcaattgagc gtgtaattaa agcaatcgct cgtaatgagc atgcaatttt accagttagt
    98521 cagccagctg attcagaaat gtatatcagc cagcctcata taattggacg tgatggtgta
    98581 caaagaagag ttatcttatc ttatgatact caagagttaa atgcatttga tacgtcttat
    98641 caatcattgc aagatattgt taaacaaatt gaaatttaat taagggagaa ggatttcatg
    98701 aatattagtc aaacaaaggg tttctttaag ttccttatct taactttact aggtattgta
    98761 tttttattga ttccatttcg gttcgaaaat ggcatggata caatattatt tcactatcta
    98821 aaattattta tttcagaaaa tcatgctgtt attcaaacaa ttgtagtctt gttggtttgt
    98881 cttagtgcaa ccttatctct tatagatcaa ttgttaccaa atacgatttt acgtaaacaa
    98941 agattactta agaaactgtt ctcaacgaca cctttctatg tatttaatag aatcatgggt
    99001 gtaattattg ctatgctttg ttatttacaa ataggtccta aattcatcat ttcaatcgat
    99061 actggtggcg caatgcttga tttaggaaca caactttctg tacttgtacc attgatgcta
    99121 ctatttcaaa cacttatttt agagtttggt gctatggagt ttttaggaca attgataggg
    99181 tttattgcaa aaccattatt taaactttca gaaatttgtg ctgtgaatat aatcagtgcc
    99241 tgggttggtc ctggtaatgc tgcaattatt ggtactaaag aactttttga aaagggatac
    99301 tttacagtaa aggaatccgc tgttatcgga agtcagtttt ccatctcaag tattggttgg
    99361 gttgtactgg tttgttaagt tttagacaca atggatcatt ttgctttaat attcttagga
    99421 ataactctga taggtataat cttagctttc ataaatgtaa gaatcccacc tatttctaat
    99481 tatcctgata cttatgttga tggttcaaca acttctaaaa ttgtctctag cacacaaggg
    99541 acacgactgc aacgtgctat tatacaatca agtatgcgtg caaaccaagt tactttaaaa
    99601 aattttacaa gtaagattga taatatgagc ttctatgttt tatggctaac acctattatt
    99661 attttctggg gggcattagc acttattgtt tcattgtata ctcctctatt aacttgggta
    99721 tcttatccaa tagaattagt attgaagtta gcaaatatct ctgaaccagc aattactgct
    99781 agcgcaatta tgtcaggatt tgcggataac tatttaccag ttatcttggg caaaggatta
    99841 gaatccattg aaagcaaaac aatcattact atgatgagca tcctacagct tatctttatg
    99901 tcagaaatcg caacattact tcagtcatgt aaagttgtaa aaagttttaa agatattatt
    99961 attatatttt tacaaagaac tattatcgcc ctaccatttg taattatatt tacaaagctt
   100021 attctataag atttaaaggt tttaaagtgc ttgaatgatt attctttaat agtctttctt
   100081 ttcataattt agattgatga acattccttg aaatatcttt tgtataaggg agtttgctaa
   100141 aatatattgt taatttttta atatttattt aatttcttat ttaaagaaat tttgaagtca
   100201 tcacttcaaa tagttatatt gaatattcta tttatttttg tgattttcaa actatcatta
   100261 tgtaaagcat tatatagcca acctggatat ctaattgaat ttgttaaaaa ttaaatttat
   100321 aaagataaaa tatgtgaatt atattaaaaa tatacataag tagaagatat agggttggta
   100381 attctaatat tacaagccct attttatatt atttatggag tctttaaaat aaagtgtgta
   100441 ttcttctaaa aagtagtgat aattgaaata ttaaatatca ctatataaag gaaggttcct
   100501 acttttagtt tatgaggcac tctttttgta tgaaatcaaa tgtattttca tcattttaac
   100561 aatgaaaaag aggcttatct ctatttttag gaagcctcta taactttata ttgaatctat
   100621 ttattaactt tgtacataca tataccactt atataagttt cgtatatatt aaagtcctta
   100681 tctgttacta taaaatctgc ctccatacct tgatgtatgg agccacaaac attatcaata
   100741 ttacaactta aagcagggat atatgtagcc atttttattg catcttctaa agtggctatg
   100801 ttccaatcaa ctatatttct cacagccttg tccatagtta atacacttcc agctaaactc
   100861 ccactattta atcttgcaac actatttttt acatttacat taaacttacc aagagtatat
   100921 tttccatcct ccatagcacc agctctcata caatctgtaa ttaaagctat gttattacta
   100981 gacttagcat ccatcattat tttaacagct attgggctta catgatgacc atcacaaatt
   101041 aattcagcat aagtatcttt tagtaccata gcagccccaa ccattccagg ttctctatga
   101101 tttaaaggac tcatcccatt atatgtatgt acaaacactt tagcacctga attaacgact
   101161 tgtttaactt gctcaaatgt agctgaacta tgaccaagag aaactgatat attattttta
   101221 gttgcatatc ttgttaattc tattgaacct ttacgttctg gagcaattgc tatttttctt
   101281 attaaatttt tcgatttttt ttgccataat tttaatatat tgatgtcagg gtttttaaaa
   101341 tatttttcat tttgagcgcc cttatatttt tctgtaaaaa atggaccttc taaataaatc
   101401 ccttgtattt ttgcaccctc aactcgattg aagctattgc ttatattttc tacagaatca
   101461 cttagtgtat ctacagaatc agttaaagtt gtaggtagga aagatgttac tccatatttt
   101521 aataagcctt ttgaaattgt gtttattgct tcaaatgtat tgtccatgac atctgcacct
   101581 aaaagaccgt gaatgtgagt atcaactaag ccaggagcaa tatatttacc tgaaaaatct
   101641 ataacattat cagtaacatt aggtctttct tgttgaaatt caccgaattt gccattaatt
   101701 atactaaggt aacctttttc tttgattcca tgtttcataa aaaatttatc tgcataaata
   101761 aaacttttca aaataacctc cttataatta tactatcatt gtggcattga cgcttataat
   101821 atcattctgt tttcttgaaa gttatttaac ttactatctt acatgtctta ctctatatac
   101881 aaatttatcg cttctagcga cactcaaagt aaattcaata actatattgt catcattata
   101941 tgtggtacga agtaatttca gacaaggtga atctcctggt acttccaata acttagcttc
   102001 cttatcagag attattccag ctgaaaattc ttcatcagca actttaataa tctcgccata
   102061 atcttctcta aatatttcat ataaaggttt ttgttcgatt ttttcttttg tcaatcctat
   102121 aaattctttc ataggaagat atgttctttc aagcatcata ggaaggtcat cagcaagtct
   102181 taaacgcatt atttttatca ttttttcacc aggagttata cctaattttt cagagaaata
   102241 ctttgtactt tctactacct caaatgataa tacctttgta cctggctttt ttccttgtgt
   102301 tctcatataa tctgtaaagc tataactttc cattaagttt tgagaatttt gacttagtgc
   102361 agcaacaaaa gttccttttc catgtctttt gtatatatat cccatatgct ctaactcagc
   102421 catagctagt ctaactgtgg ttctacttac tccatattca tcacaaattt ttctttcgga
   102481 aagcattcta tcgtttggtt ccatctcatt ttcaatctta gttcttaata tctcaacaag
   102541 ctggtcatat attggtcttt tatcatttct ttttatcata aaaatatagt cctttctaag
   102601 tggttattac cacaatttga ttatagaata tagaattatt tatgtcaatg aataaagttt
   102661 aatcaaaatt caataagtaa ggctattaat ttattataaa attatggtac attgacaaaa
   102721 caagtaaaat aatttatatt caaattggta ataaccactt tggatatatt atatgaggta
   102781 ttttttattt tacagattaa tttattgttt agaaaagtaa aaattaataa tgaggagaat
   102841 ctagtatgat tacagtaata acattcaacc catctataga tagaatgtat agagtgaata
   102901 atataaacat aggtgaggtg caaagggtag taagtaagaa tgcaactgct ggaggtaaag
   102961 gattaaacgt agctaaggta tgtaaaattt taaaagaaaa tcctttagct atgggatttc
   103021 taggcggatt taatggagaa tttataaaaa atgaacttag aaaactagat atacaaaata
   103081 aatttacaaa aatagagcag gaaactagaa attgcttaaa cataattgag gacaataaag
   103141 ttagtacaga atttttagaa aaaggaccaa tagtagaaaa aagcgattta gagagatttg
   103201 aaaatgatat agaggaagta ctaaaaaata ctaaaatact ggtagcttct ggtagttatt
   103261 gtgagaatat gccgatagac tattatgaaa agataggaaa tatatgtaga gcaaataata
   103321 taaagtttat attagataca tcaggagaag cattaaaaat agctttaaaa tcaaaaccat
   103381 atttaataaa gccaaatata gatgaaataa gacatttatt aggaatgaat atagaatcaa
   103441 gagaagaaat tatcttgtca ggaaaaaaac ttattgaaat gggtgcagag aatgtatgta
   103501 tatctttagg aaaagatggt atggtgtatt taaacgaaga taatgtatat gatgtaaaag
   103561 taccagttgt aaagtgtata aatactgtag gtagtggaga tagcacagtg gctggattta
   103621 gtgtaggtat tttaaggggt tataaaatag aaaatttact taaatttgca aatgcttgtg
   103681 gtataagtaa tgctttaaat atggaaactg gatttgtaga tttggtagaa attgataaat
   103741 atcaagattt agttgaagta aaaaagttaa gttaaataca tttaatggga atataataaa
   103801 tttaatgttg ttgtaataga ttttaatttt aatataaaag atatagtctt atataaaaat
   103861 aggttagaaa aattcatttt taacctattt ttataataaa tatctatttt actgaattta
   103921 taattttctc tagtaatctt tgagccttga tacactcttc tccattaata gctggtttta
   103981 tattattttc tatacaatca ataaaatgat ttgatatatc ctcaaaaccc ttttgtttta
   104041 atatgtttac ccatgcacca ctttgcttta aagttaggtt tccaccttct tctatttcca
   104101 gtacattaag attcttaact ctttgaatat taccctttga aagaatttca acttgttcta
   104161 actttgttcc agaatctcta tgcatagagg tgtttataga gaaattttta cctttaagtt
   104221 tatgacttac aaatataaga ttcttattgt ctgttaaaaa taaatcctct ccactaattt
   104281 caacatcttc atttgctaac cataaagcag tgtcaataac atgtatatag tcatctataa
   104341 gagtactgtc gaatttaaca tttcttaagg aatttaatcc atgtttacat atattgatag
   104401 atacaatttc tgtagcatta tttttaattt ctttgtacat aggacagaat ctacggttga
   104461 atccaaccat taaatttaag ttttttttcg tacttaattc gataagttct tctccttgac
   104521 ttactgttga agcaagaggt ttgtctacat atacatgaac acctaaattt aataatattt
   104581 ttataatttc gtagtgtgtt tctgtagagc tatgtagaaa aatacaatca cattttttag
   104641 ctagggattc aatagaatcg aatggcatga ttctataatc actacagact ttttcccttt
   104701 taactttatt tggagtaaaa gctcctacaa actcaaatct ctcagactta gttaatatag
   104761 gtaaatatgc cttttgagct atggagccaa gacctatcat tcccattttt atatttttca
   104821 taatactttc tcctaaggtt tttatattta cagaattgat tataattcag acacataaat
   104881 ttgtaaactt tgtattaaaa aataaattta aagcttatat aagtaaatta gcgaaataag
   104941 aaatattgat aaagtaattt tgtaggatat ccataaaatt gattgatata aatattttat
   105001 gtattgacaa aaaattcaaa ttaatttata tttggattag tggtaattac cactttggtc
   105061 tgaacaagtt tttatcgtaa aataaaaata ctaaagtata tagagtatga ttttattaaa
   105121 tttttaaaga taaactataa aattaattaa aatctatagt gtatatttta tagtgagttt
   105181 aagtagtact aaaaaatcta agcaaaaaat tataaaagag tatatttttt tatagtttaa
   105241 agtggttata acctcattac caaatgtaaa cgttacaagt atgaaaggag aatgaaaatg
   105301 tttaaattag aagaacaaaa actaaaagat ttaggtgcaa taataacaac taatgaaata
   105361 aaacaacagc ctgaattatg gttagaaact tatgaaatat ataaatctaa caaagaaaaa
   105421 ttaagtagat tcatagatac aataagtaat aatcatgggc agtttagagt tatatttaca
   105481 ggtgctggaa cttcagctta cataggaaat tcaatacttc cttaccttaa aaataaaaat
   105541 gacataagaa aatacatatt tgaagcaata cctactacgg atatagtttc aaacccatat
   105601 gattacttaa aaaaagatat accaacatta ttaatttcat ttgcaagaag tggaaatagt
   105661 cctgaaagtt tggctgcttt aaatttaggg aataagattg tagataattt ttatcattta
   105721 gctataactt gtaatccaga aggagaactg gctaagatga ctaaaaacga cgaaaataat
   105781 tacttgttat taatgccatc aaaatcaaat gatgaaggct ttgccatgac aggaagtttt
   105841 tcgtgtatga tgttatctgc tatgttaata ttcgatagtt tagaagatga tgtagaaaag
   105901 tcatatataa atgcaataat tgaaatggga agaaatgtta tagatagaaa agatgaaata
   105961 catgagttaa taaataaaga ttttgataga gttgtatatt taggttcagg aggattaggt
   106021 ggtttgacac aagaagcaca actaaaactt ttagaactta cagccggaaa aatatctaca
   106081 gtgtatgatt ctcctatggg gtttagacac ggaccaaaat catttattga tgaaaataca
   106141 cttgtatttg aatttgtatc taactgttta tatacaagaa aatatgattt agatgtttta
   106201 gaggagataa aaagggataa aattgctaaa ttcacttgtg cagtgtcagt agaaaatgaa
   106261 aataacttct caggaacaaa gtttgagttt aaagaaaagt ataataaatt accagatgtg
   106321 tatcttgcaa tgccatacat attgtttgca caaactatag cattgtttgt atcggtaaag
   106381 gttggaaata agccagatac tccatcagct acaggaacag taaatcgagt agtaaaaggt
   106441 gtaacaatat atgaatatta aaagataaga ttaaaatatt ataactaaat aatttgggag
   106501 ggtatcaatg tggcattagt aacaacaaca tcaatgctta aaaaggcaca agatgaaggg
   106561 tatgcagtag gagcatttaa tgtagaaaat atggaaatgg taattgctgt tatagaagct
   106621 gctgaggagt taaattctcc agtaatatta caaactactc catctactgt aaaatatgca
   106681 ggtcttgatt attatctagc aaatgcaaag gttgctgcag aaagagtaaa tatacctgta
   106741 gcaatgcatc tggaccatgg ttcaagtttt gaccttgcaa tgaaagcttt aagaagtgga
   106801 tatacatcaa taatgataga tggttctcat gaaagctttg aaaataatat atctatatct
   106861 aaatcagtag taaaagcatg tagtccttct cttataccag tggaagcaga acttgggaaa
   106921 gttggtggaa aagaagatga tttagatggc gggaatagta atgattatac aaatccaaaa
   106981 gaggcaaaag agtttgtcga tagaacagga atatcttcat tggctattgc tataggtact
   107041 gcacatggat tgtataaggg tgaacctaaa atagatttag ataggttatc agaaattaaa
   107101 aatgtagttt caataccttt agtattgcat ggaggttcag gaatacatga tgatattata
   107161 aaagaagcta taaaaagagg tattgcaaaa gttaactatg caactgaatt aagaattgca
   107221 tatagtaaag gggttaaaaa agttttagat gaagattctg aggttataga ccctaaaaag
   107281 tatggattag cagggcttca atcagtaaag gattttgtga aagaaaagat taaagtgtgt
   107341 gggtctgtaa atagagtata aaaataaaat atcctaaatt tattttagat aagtttagga
   107401 tatttgttat atgaaaaatt tatattaatt atatgtaaat ggtgtatttt tttcatttaa
   107461 ttgatgaaaa atatcagctt ttattggtaa agtattacat atataattaa aatatactaa
   107521 aaattgaact atatatttta ttattataaa atatttatat taaattgtgg aattaaaata
   107581 tactaggata taaaattctt aaataaaaag aaaagattgt ttttataaaa aatatttttt
   107641 ataccacttt aaaaaacaca ataataacac tgagggaggt ggggatatga gagaacgcat
   107701 tattcttgaa acattaaaaa atagtagtgg ttatctaaac atagattatt ttgcagataa
   107761 gttgggggta tctactcgaa ctatcagaaa tgaaataaaa aagatagaaa ctataaaaga
   107821 atgtaatggt tttaaattag aatataagtc taaattagga tatattctaa atattaaaga
   107881 ccaagataaa ttcgagcatt atctaagaaa cttaccctca gatttagttg aaaatccaga
   107941 acaacggttg gagtctataa tagtagagct tttagtaaat gaaggttata aaactataga
   108001 acagttaagt aaaaaatttc tagtaagttc atcccaaata aaaaatgatt taaaaaagat
   108061 agatgaaaag ataaaggata cagaattaaa actagagcga aaggctcatt atggaattaa
   108121 aatagaaggt tctataaaag aaattcaaag tatattggtg gatagttatt ttagagggaa
   108181 tagaaatata acagagtaca ggaataagtt tatagataat ttaaaattag ctaatattag
   108241 aagtacaata aaaaatgtac ttaatgaaca tgatttagaa gcaaatttaa cagaacttga
   108301 ggaaatatta gcacaaatta ttatattgta tataagagtt agtatgagag tagtgggaaa
   108361 tgctagcgat ttaaaattat atacagaaga tttaattata gataaattat tagataaaat
   108421 ttttagagat aaaaaatata accttaatta tgatgaaaag tattatttaa aggagcttat
   108481 aaaactaaag actaaagata agaaagccac tataaagaat attgataaga ataaacttca
   108541 agatattatg ttcgaatttt ttagagagat agataaaaaa tataactcta attttttaga
   108601 agataaagag ttttttaact tattttactt acatattgca tgtttaatag aacgtataaa
   108661 gaagaaccac aagataataa atcctttttc agttaaaata agtcaacagt atccaactgt
   108721 ttttaactta tctattcaat tttcaaaaat catagaaaat gagtatcata taaaaataag
   108781 tcaagatgaa atagggttta tagctactca cattgctgtt ccttttgaaa agagagaaga
   108841 agctaatttt aataaaaaat ataaaatagc aataatatgc tcttctggtg gaggtagtgc
   108901 atttttgata aatttaagac ttaaagaaat ttttccaaat gctgagataa gaaatttttc
   108961 attactagaa gaaaaagctg taatagaatt tgcaccagat ttgatttttt caataacaaa
   109021 tcttttattt gaaataaatg ctccagttat acttataaat gaaattttag acgaattgga
   109081 ttatttagat attaaagaaa gtgttagatt tgcagaccat ataggaaata tatcaagccc
   109141 aaaacaatat atattaggtc tatttgataa gaatcacttt aggtgtataa aagataaagc
   109201 taagtataag gatatccttg atagtatgtc aaaatgtata gttgacgagg gagcttgttc
   109261 tccaacctat cccaaagatg tatgggaaag agaaagctat ttgagtacta tttatacaaa
   109321 tggggtggct atacctcatc caatcgagat gacaggaaac aaaaatataa tatcagtagc
   109381 tttgatacaa actgatatta tttatgaaaa tagggtgcct aaaattattt tcatgatttc
   109441 attaataaag ggaaatttag aacttcataa gcaaatatct aaatatttaa gtaagattat
   109501 ggcaaataag gatatggtag acatgctaaa taagtcacaa tcttatgaag agtttatgta
   109561 taagttaaaa atctatctgg gaggttagac atgaatatag agttttttaa gaggttgtca
   109621 gaagcagatg gtatagcatc taatgaagaa gaggttagac atgttttatt ggaagaacta
   109681 aaagcttata gtgataaaat tatctgtgat gggctaggga gtatcatctt ttctaaaata
   109741 aaagatgaga gtgcaccaaa cgtaatgatt tgtgctcata tggatgaagt tggatttatg
   109801 gtgagaagta tagacaaact tggtatgatt cacttaataa caataggagg agtaaaacct
   109861 cttgcacagt ttgtacaaaa agttagaatt acaacaaaag aagggaagaa aatccccgct
   109921 gtcataaatg ctacatataa taatggtaag gctgaaaata tatatgcaga tattggagca
   109981 tatacagaag aagatgtata taacctaggg attaatgttg gggatatggt aacatataca
   110041 acaagctttg aggaatttac tttaccagac cgattagtgg gaaaggcttt tgatgatagg
   110101 ataggatgtt ttgtgatggg agaagtttta aaagaactta ggaaagaaaa tctaaattgt
   110161 aatattcact ttgcggctac aagtagtgaa gaggttggaa taaggggagc aaagacatca
   110221 acacagctaa taaatccaga tatagtattt gtaatagatg tagcatgtgc taaaaatgag
   110281 tttgtgagag actatacaaa tcagaaacaa attgataaag gtgtaatgct aatgcataga
   110341 gataggactc tagtccctag tagaaaaatg atagattatg taatggaaat tgctgataaa
   110401 aataatatac cacttcaaca tgatatgttt gaatcaggtg ggactgatgg aggagaagca
   110461 catctcgtaa atgaagggaa accttgtgta gtaacttgtg taccagttag atatggtcat
   110521 tgtgcatttt caatagtaag taataaagat ttggagaaca ttataagatt gtatacacag
   110581 ttaattttaa attttgatga agaacaatat aaacatataa gaaattttat ctaaaggaga
   110641 ataagaaaat gtcaacagaa gtacaaataa tggaacttat atcaactgca ggagagagta
   110701 aatcgaaagc ttttgaggct ttaaaaaaag tgaagtcaaa agattttaaa ggagcaaaat
   110761 tgttaataga ggaagctcgt aaaatagata ttgaagctca caggatacaa acagaattaa
   110821 taactcaaga tttaaatgaa gatgttgaaa gtccagcaat gagtctttta atggtacatg
   110881 ctcaagacca ctatatgact tctcagctag caaaagactt gatagaggct ttgatatatt
   110941 gtctcgataa gtaattgtaa tgtagaaata gattatttat gtaaaaattc ttttaaaagt
   111001 ttagatgctt ttaagagata ataaaaatac aaactttagg aggaattatt atgaaaatat
   111061 tattatgttg tgcaggtgga ttttctacta atatgttaat gcaaaatatg aaaaaggtgg
   111121 taaaagagag tgctaaactc aatgaaaaag attttgagtt tacagctata ccagcagatt
   111181 caatagaaag tgaagttgat gattgggata tagtacttat aggtcctcaa atagctcaca
   111241 aaatagactt cttaaaagga atattagagc caaaaaataa gccttttgca gtaatagata
   111301 aagatgtata tggaaaaatg gatggagcta cagttatgaa gttggcatta ataacttata
   111361 agaaacatca attagctcaa ggataataaa aataatgagg gaaaagggag attagatatg
   111421 ttttcaaaat ttgaagcatt tatgaataga gtatttatgc ctttagctca taaggttgac
   111481 aatcaacgtc accttggttc tataaaggct ggtatggttg ctatgacacc attcacaata
   111541 ttaggaagta tatttgcaat acttccagca cttccaaata tgcttggaga aaataatcca
   111601 ataagcaaat tcatacttaa caattcagca atattggatt taccagtaag tctttccata
   111661 ggtttaatag gattatatgc ttgtatgtgt attgctttta atctggggaa ctactataaa
   111721 ttatatatac caggttgtgt tgcactatca actttttcct ttttattcct agtagcctca
   111781 tttacaccag atggagcttt agaaatagga aatttaggag ctaaagggct atttacaggt
   111841 atgatagcag ggcttggttc tgtggagtta tataattttt gtaataagaa gaatatcaca
   111901 ataaaaatgc cagaaaatgt acctgatttt gtatctaggt cttttgaatt aatacctact
   111961 actataatag tttgtggaac ttttatagtt gctcgtttta tttcattaaa agtatttgga
   112021 gaattacctc cacagatact tactcaattt ttatctccat tagtaggaag tatggataac
   112081 ccatggtcag ttcttgcact taactttgct atatgtacta tattcttttt tggaatacat
   112141 tcatcagtat ttagtcctat aactagacct ataatgatta catttatagc tgaaaacata
   112201 gcagctatgc aagctggaga aacaatacct catttcttta cagcaggagc ttcaagtgca
   112261 ttctttggat ttacaggatg tggaattagt ataggttgtg taattgcatg tatgttatca
   112321 aaaaatgctt cctataagaa gattggacgt gtatcattat tccctgcatt atttgggata
   112381 aatgaaccaa tattatttgg agcaccgata atattaaatc caataatgtt tataccacat
   112441 gtatttggtg gagctataat aggtacacta ccaatgtttt ttatgcactg gggatggtta
   112501 gcaaagccag tatttgaccc tccatatgta ggggtattct tagaaggatt tttaactaat
   112561 ggagattggc attctatatt agcaaatgca ttgcaattag tattagcagt tttattatat
   112621 tggccattct ttaaaataat ggaacgtcaa caaaataata aaaaacaaaa agaagaaact
   112681 aagaatatat tctctaaaga agaagaagac ttattggatg atttaggatt ggatttctaa
   112741 tattttgtta tgaataatac aatggagaga ttagtatcct taatctataa aagaggtgtt
   112801 gacgctcttt tgattaaagc aaaaaatact aaaagatata taggagcttt atcaggtagt
   112861 ggtgtatatg tgcttgttac taaggataaa aattatcaaa ttctagatgg cagatatatt
   112921 gatgaagcag ataaaaaaac gactggtttc ataaaaagga ttgtatctca aggttcttat
   112981 ataccaacta taattgagtt attaaaagaa ttaaatataa aaaagttagc aatagaaaac
   113041 caagctatga gtatacaaga gtatctttca ctaaaaaatg aaggttttga aatcaattta
   113101 ataacaaatg aattatggaa gctaagggct ataaaatcta aagaagaaat tgaacttatt
   113161 aaaaaggctt gtgaaattac agatgaagta tttgatgagg ttatttctga aattaaaaaa
   113221 gatatgactg agctagaagt atcagctcta attcagtatc atgcattaaa aaaaggtgca
   113281 agtggaatgt cttttgaaac aatagtggta tcaggagaaa gaggtgcaat gccacatgga
   113341 agacctacaa acaaaaaatt gaaagtgaat gaagctataa caatagattt tggtgttgtt
   113401 tatcaagggt atcaatcaga catgactcgt acaatatcta taggtaaacc tcctaaaatt
   113461 attaaagaga tatatgatgt agtattggaa gcacaattat ctgcaataga gtcaataaag
   113521 gaaggaacta gggcaagtga tgttgacaaa gtggctagaa aaattataga taaacatgga
   113581 tttggcgaat attttaatca tggactgggt catggtatag gtcttggaga tggtgaagtt
   113641 cccactttaa atccaaatag tgaagatata ttagtggaag gaatggtaat gtcttgtgag
   113701 ccaggtattt atattccaaa tgtaggggga gttagaatag aagatgatat tgttataata
   113761 gatggaaaag gtgttccact caataagaca tccaaagagt ttataatatt aggagagtaa
   113821 aattatgaaa tataatttta ataaagtatt aaatcgtaaa gaaggaaatt gtagaaaatg
   113881 gagcaaccat gtgattaaag aaaaatttgg cttaaatgaa gatgcaattc ctatggattt
   113941 agctgatatc gattttgagt gtgctcctgc tataaaagaa tctatcttaa aaagagcatc
   114001 agtaggagat tatagttata cttttatagg agatgacttc tatgatgcta ttataaattg
   114061 gaataaaaga agatttgatg tatatataga aaaggattgg ataaaattaa cttttggtac
   114121 tgtttcaacc cttcattata tagtccaagc atatactaaa gaaggagagg gtgtattgat
   114181 aaatacacct gcttatgacc cttttgcaga ggctgtagta aataataata gaaagttgtg
   114241 ttgtagctca ttaaaattag ataacaatag atattattta gatttagagg atatggaaaa
   114301 tcaaatgaaa tacgagaata taagattgct tatattctgt agtccacaaa atccatcagg
   114361 tcgtatatgg acaaaagaag aactatatca agtgtcagag ttatgtttaa agtataatgt
   114421 aattttggta agtgatgaaa ttcatagaga tataatattt aaagattata gatttgtatc
   114481 tttgtggaat gctcatccag aaatttataa aaatagtata atctgtgtat ctcctaataa
   114541 aggcttcaac ttaggtggat taaaaacatc atatgtatta ataagagatg taaaaattag
   114601 ggagacttta ttagaaaggc taaaaagtaa ttcaataact tctccaaatg tatttgcaat
   114661 accagcaata gttgcagcat ataatgaaag cgaagaatgg ctagatgcta tgactagtta
   114721 tgtagaggag aattttgaaa tagtttatga tttctttgaa actaatatac caaaagctaa
   114781 agtgatgaag tcagactctt cttttttagc ctggatagat gtaagagaag tatttagaaa
   114841 tgaagaagaa tctaaagaat tttttagaca tgcaaactta actatggtag ttggaagtta
   114901 ttttgtgaaa gatggagatg gatttattcg tattaatgtg gggtgtccta gagaaacatt
   114961 aaatgaggct ctaaatagaa tcaaaaaaac gtatataagt atgtattgtt aaatcataaa
   115021 aaaagtatct atggtttata taaaaacaca ttatttagtt atcaaatatt actggaattt
   115081 tgtattccag taatattttt tgattaagga atattattga ggaatattaa ataatattat
   115141 ttcataccct tatattaact tatataaaaa tattttatta ttttgggaac gggttagcta
   115201 acctttatct agtgtatatt tatattgtaa gaagcagtaa aaacttttcc tttactaagt
   115261 ttattaataa acttcttatc tttataaatt ttgttagaat ttatactatc agcaagacca
   115321 taccaaggtt ctatacataa aaaaggagca gtagaattag tttcactata ataaggagtc
   115381 caaataccaa ctagagggaa atcttccata gatatagtta catatttact accatcatta
   115441 ttacatatag acacttcatc tatgttggtg tatatcaaag catcattctt gaatacttct
   115501 ggatttaact gtaagttttt taattttcca ataggtatta tatcatctgt aaaagaacca
   115561 tttaaattga ttttttctac atcattttta cttttaaact caaggtagtg tttagaaaaa
   115621 tcattttgtt cgtaaaaagg aaggttgaat gcaggatgtc cacctataga aaagaatata
   115681 tctttagaat cagtattttt tacaatccat tctacctcaa tactattatc atttaatgta
   115741 tagtttatga ttagctcaaa agaatatgga tacttcttta aagtagattc attatctgtt
   115801 aatttataag ttacaaatgt atctccttta tctacaatct caaagtccat atctctagca
   115861 aacccatgtt gagtcatgct atataaattt tcttctatta ttgtttcatt atcaaaaagt
   115921 ttacctacta tagggaacaa tataggtgat tgtctacccc aatatttttt attaccatcc
   115981 caaagaacgt ttttgtcgta ttttttagaa aatattttag ttagttcagc accaaaactg
   116041 cttgattcga taattaaatt ttcattttgt aatatattca tttaaaatct cctttattat
   116101 attttatgag tatattatac tataaagtat aaagattatt aaattttatt tgatattata
   116161 tttgaaaggt agattttagt atattttgaa aattttgttt tgaaaatttg ggattattta
   116221 agaaattttg tattataaat agaaggaaat agataaattg tatagaataa aatatattaa
   116281 gataagttaa taatgttaaa tgggaagtga gtttatggaa aaaccaaata caaaagttgt
   116341 taactttcaa gagtataaag acagaaaaaa ccaaagagaa gtaaatagag acgaactttt
   116401 aaagcttata aaaaaaattg tgacttcaaa atagggagtt gttaaactcc ctattttaat
   116461 gggtttcata ataattaaga cattctaagt ccatctatat aatctttgaa ttgtgagaaa
   116521 tctgattcac tacttaattc tatggtttct gaaccttccg tataaaaatt cttaagatag
   116581 atagtataat tattatcaac acaatcatga taaatacatc tatatccatc ttcatacaaa
   116641 ctttttaatt tagaaaaatc atccacaata tcatctcctt aaagttcttt taaatatatt
   116701 tttacaaaaa gcatctaatt gtatgcaaat tgacaatgta aaataaagga aatgaacata
   116761 aaatgtagaa taatttttat atgtatgtaa aaataaaaag aaaaagttga aatttttaga
   116821 aaataagagt attttttatc taaaaagaga gtttaaaaaa taaaaaaatg ttgggaggat
   116881 aaaaaatgag tttattagaa agtatatcaa aaaacatata ttccctagat aactcttcta
   116941 ttgaaaaaac aaagcagaga ttggataggc ttatacatcc aactggaagc ttaggaaaga
   117001 tagaagatat ttgcatgcaa ttagcaggaa tatttggcaa tgaaaatttt gacacaagta
   117061 aaaaggttat aattgctttt gcgggagacc atggtgtata tgaagaaggc gtagcacctg
   117121 accctcaaaa tataacaaaa ttacagtttc caaatttttc gaaaggtcta tgtggagttg
   117181 gagtaataag taaatttgta ggggcagatg ttgtagctgt agatgtagga ataaactgtg
   117241 atgaaaaact ggatggggta ttagactaca agataagaaa agggacatca aatatggcaa
   117301 aaggtccagc tatgagtaaa caagaagcaa ttagatgttt agagataggt attgaaatag
   117361 cagagcagtg tatagaaaaa gattataagg ttattggtat tggggagatg ggtatagcaa
   117421 atactactcc aagtacagca ataatatctg taatttcagg gtgtgacccg ttagaagtta
   117481 ctggtatagg tgcaggtctt aagaaagaaa gactaaagca taaggctgaa gtaattagaa
   117541 aggctattga aattaataat ccaaatccaa ctgatggagt agatatttta tctaaagtag
   117601 gaggatttga aataggctca atggcaggtg ttatattagg ttgtagtgct aataggattc
   117661 cagtagtaat tgatgggttt atttcttatg cagcagcatt aattgcatat aagataaatc
   117721 caaaaactag agaatatatg atagcatctc atttatcagc agaatcagga actaaaagag
   117781 cattagacat attaaaatta gaccctctat taaatatgga tatgagatta ggtgagggaa
   117841 gtggagctgc tttagcattt gatataatag aagcttcaaa ctatacttat aaaaatatgg
   117901 caacttttga tgaaattgac atgggaagat aaatataaaa atttaatatg taggagtgtt
   117961 ttgatgagta aaattattct agtaacagga ggagctaggt cagggaagag taactttgca
   118021 gaaaaactat gttttgacag aaataataat acagcttata tagcaacctc tattccattt
   118081 gatgatgaaa tgaaagatag agtaaaaaaa catcaagaga atagacctag aaactggaat
   118141 acttatgaaa tatatgaaga tatatattcc ataattaagg agatatataa agaacatgaa
   118201 actgttatac tagattgtgt aacattatta gtaaataatc taatgtttga acacaattta
   118261 aatatagaag aatctagtca agaagaaata aacaaattag aacaatacat aaaagaacaa
   118321 gttgtcaaac ttattgaaga aatagaaaaa acaaatctat actttgtatt tgtaacgaat
   118381 gagttaggta tgggaattgt tcctgggaat aaacttagta gaatttatgc tgatattgta
   118441 ggtcgtataa atcaatatat agcttcgaaa agtaatgaag tttattttgt agttagtggc
   118501 atagctatga agataaagga gtagtatgca attatgaaaa gatttatttt aatactacag
   118561 tttttgacaa ggatacctat aaaattaaat gtaggatttg atgatgaatt ttataagtca
   118621 atagtatatt ttccacttgt aggttttgtc ataggtatat tatcctattt aataggatgg
   118681 atttctatgc ttttatttga accatttata gcttctataa taataactct agctggtgtc
   118741 ttaattactg gaggacttca tatagatgga ttaggagata catttgatgc aatatatagt
   118801 tatagagata aagaaaaaat gcttgaaata atgaaagatt caagattagg tacaaattca
   118861 cttctagcaa ttatgtttgt acttttatta aaggttggat tcgtttacga tataataagt
   118921 aataattcat tgtgggttat aatttttatg ccaatgattg caaggttagg agtaatgtta
   118981 ttgacatata aaactgtgac accaagagaa aaaggaatgg gaaatttatt tataggaaaa
   119041 ttaactacaa gtatgttaat aactgctata atatacacat tattgatagt tgctcttatt
   119101 actaaattta tatttttatt acctaatata gtgttgatta aagtattagg ttcgattata
   119161 gtggtttttg tatttataat attattcaaa aaacatattt ataaaaaaat tgatggagta
   119221 acaggagata tattaggctg tggaatagaa ctttcagagc ttgtatattt aatttacata
   119281 tatttgttaa tttttatgtt tttttaaagt aaaaagtggt gataatatga taagattaat
   119341 attaataaga catgcactga caaatgataa taaaaaagga agattatcag gccatataaa
   119401 tagttgtatt agtgaagagg gcaaactaca aataaataaa attaccagat atctgagtaa
   119461 tgaaaacata gataaggttt atacaacacc atctacacgt actaaagata cagtagaaaa
   119521 aatatcaaaa ttgaaattat tagaaataga agaaaaagaa gctttaagag aaattagttt
   119581 tggagacttt gaaggaagaa cttttgaaga aattaaaatc aaatatccaa atgagtttga
   119641 aaaaatgata aaagaaggta acaactatag atatccaaat ggagaaagtt tgatagactc
   119701 ttataaaaga gtggcaaaag aaattgataa tataatttta gaaaatgata gtaatttaga
   119761 tacaaagaca atacttatat gttctcatgc aggaacaata agaaatataa taacacattt
   119821 gatttctggt agttataagt atcactggaa ctttaaaatt gataatgcat ctattacagt
   119881 tttagaaatt gatggtggat ttgctgtaat agataaaatg aattttacag acttcatata
   119941 atttaatcaa aaccaaacat tacaatctgt gtttgtaata tatctgtaaa attagcaatg
   120001 aaaatagaat attagattaa aattaggttc ttaattagat gttaaaaggg aaaaaggtta
   120061 gatgcctttg cagcccccgc tactgtgaaa ccaacgaaac tataaatacc actgtcagtt
   120121 tgatgggaag gttatagaag taggatgaag ttaagccagg atacctgcct aatttaattt
   120181 aaaacaagag gtcttcgggg tgaaagattt ttaattaata tatataaaag tcctatcttt
   120241 agaagtatta ggactttttt taatttgttt tttagtaaat tttaacaagg agggatggaa
   120301 agtggggaaa aaaataatgc tacaaggaac agcttcaaat gtaggtaaaa gtgtcttagt
   120361 agcaggtttg tgtagaatat ttaagcaaga tggttatact gttgctcctt ttaagtcaca
   120421 aaatatggct ttaaattctt ttataactaa agaaggatta gaaatgggaa gagcacaagt
   120481 atttcaagca gaggctgcga aaatagagcc aatagctgat atgaatccag ttttattaaa
   120541 accttctgga aataataaaa gtcaagttat tgtaagaggt aaagttgtag gagaaatgcc
   120601 ttcttctaag tatcatgatt ataaattgga gttagtagat gtgttgaagg aaacatttaa
   120661 tagcttaaat tcaaggtatg atattgtagt tatggaaggg gcaggaagta atgcagagat
   120721 aaacttaaaa gatagagata tctctaatat gggtatggca gaaatagctg atgcacctgt
   120781 aataatagtc ggagatattg atagaggagg cgtatttgcc tcattagcag gaacaatgct
   120841 tttattaaat gaagatgaga aaagaagagt aaaaggtgta ataatcaata aattcagagg
   120901 aaaaaaagag cttttacaag atggtgtaaa gatgctagaa gacatcataa aagtacctgt
   120961 tataggagta gtaccttata cagatataaa aatagaagat gaagacagtg taactacgag
   121021 atttaagaaa aaaatgaata aaagtgatat acacatagaa ataattagaa ccccacatat
   121081 gtcaaatttt acagatttta atatatttga gacacaagaa gatgtaagta ttagatatgt
   121141 agactatgga gaatctttag gaaatccaga tatattaata atacctggaa ctaaaagtac
   121201 tatagacgat ttaacatata taagaaaaag tggtcttgaa tcgcaaatca aaaatttaca
   121261 tagtcaaggt aaattgatat ttgggatatg tggtggatac caaatgttag gtaaaaaatt
   121321 aaaagaccct tatcatgttg aaagtgaaat tgaagaagtt gatggaatag gtcttttaga
   121381 tacagaaaca acgtttgaga aagaaaagac tacaacacaa gtagaagcta ctattgttga
   121441 atgtatcagt gaatacatga ataaccttaa gggaaaaaaa gtaaaaggtt atgaaattca
   121501 tatgggaatt acaaagcgag gtaatgatgt aagaagttta gatttaataa ctaaaaaact
   121561 tgataaagaa gtgaattata ctgagggaag tgtaaataaa gaggggaatg taattgggac
   121621 ttatcttcat ggaatatttg atgaaataag ctttacaaga gcaattttaa acaatataag
   121681 aaagaaaaaa ggtttaggag aattagaaag caaagtaaac tcttttaatg aatttaagga
   121741 taaagagtat gataagttgg ctgatttttt aagagaacat ttagatatag agaaaatata
   121801 tgagattatg aaataatgat gacctttatt tataatttaa gtaggaggtg tattatgaaa
   121861 aaaattttaa ttgcgggtac taatagtgga gtaggtaaaa caacaatatc attaggaata
   121921 atgcaagctt tggttaagag aaatatgaaa gtacagccat ataaagtagg gccagactat
   121981 atagaccctt catatcacac ttttataact ggaagacatt ctagaaattt agattcttat
   122041 atgttagatg atgaaaaaat aaagtatata gtaaataagt cctcaaaaga tgcagatatt
   122101 tcagtaatag aaggtgttat gggcttatat gatggctttg gaatagattt agataattgt
   122161 acaagttcac atacttcaaa ggtattaaag tcacctgtta tattagttat aaatggtaaa
   122221 tctatggcag catctagtgc tgctatggta cttggatata aggaactaga taaagatgta
   122281 aatataaagg gtgttatagt aaataatgta aagactaata gccattatca aataattaag
   122341 agttctatag aaaaatattg taatgttgaa gtattggggt attttcctcc aaataacaaa
   122401 ttctctttgg aatctcgaca tctaggatta gttcctagtg tagaaatgaa atcactaagg
   122461 gaaaaatttt ataccttagc agatgaaatt gaacactata tagatattga cagaataatt
   122521 gaaatatcag aaagcgatga atttgagagt gattttgatt ttcaaacttt aatagaaaat
   122581 aataaaataa aagaacatgt taataataaa tcaatagcta tagcatatga taaagcattc
   122641 aatttttatt atagagaaaa tatagagctt ttagaggaac ttggtttaga aataaactat
   122701 tttagccctc ttgaagatgt atcagtgcca aatgcagatt atatttatat tggaggaggt
   122761 tttccagaaa tatttggaaa agaattagaa gcaaatgagt caatgagaac ttccatatta
   122821 gaagcacata acaataatat acctatttat gcagaatgtg gaggactgat gtacctaggt
   122881 gagaaactat tgaatcaaga agaacaagaa tttaatatgg ttggaatatt tagtggaatt
   122941 agtaagatga catcttcttt aaagagattt gggtactgta ttggtgtagc caaggaaaat
   123001 actcttttat ctaaaaaagg ggaatctatt aaagggcatg agtttcatca ttcaatattt
   123061 gaaagtgatg aaaaatgtgt atattcaatg agaaaagaaa gagatggaaa tatagtagaa
   123121 gagtgggatg gtggttatag taaaggaaac actttggcta catatcttca tactcatttt
   123181 tataataact taaattgtat agaaaatttt ttgaaaaaag gaaatgaata aatgagtatt
   123241 ttatctattt atataggata tgtgacagac ttaattgtag gagacccata ttcttttcct
   123301 catccagtga gatttattgg taaacttata aattttactc aaggtataat aagaaaggtc
   123361 tctaaaaatg ataggcagtt aaaatttggg ggatttatat tatggtttat aaccgttgga
   123421 ataacatatt taacaactta tgttatagtg aagttattta gttttaatat attattgagt
   123481 attgtagtga atagttttat aatttataca acattagcca caaaatgttt aaaagacgaa
   123541 gcattaaaaa tttataatgt attaaaaact gaagatatag aaaaatctag gattcagcta
   123601 tcttatatag taggtaggga tactactaat ttaagtgaac ctgaaataat aagagcaact
   123661 gtagaaactg ttgcagaaaa tactgtagat ggtataattg cgcctatgtt ttatgcattt
   123721 attggaggag caccacttgc tatggcctat aaagctatca atacattgga ctcaacagtt
   123781 ggatataaaa ataaaaagta taaagatatt ggttttgcat ctgctaagat tgatgatata
   123841 gccaattata taccagctag aatatctgtc attcttatga caattggaag tttcttttta
   123901 aattataact ataggaactg ttttaaaatc tctattagag atagaaagaa tcataaaagt
   123961 ccaaattgtg ctttttcaga aggtgcagta tctggtgctc taggaataca actaggaggt
   124021 accaacgttt attttgggga aaaagtatat aagccaacaa taggggataa gcttagggag
   124081 atagataaag aagatataat taaaactaat aaaattatgt atgcatcttc atttgtatct
   124141 atgttggtat ttacactaat atatgtgtta tgtaggatga ttttaattaa cttaattata
   124201 taaattattg tttgttaact taagggggac atagatgaag gatttagggc atggtgccaa
   124261 tgtagatgaa atggcaagat tatatgggaa aaacccaaaa gaaataattg attttagttc
   124321 aaacataaat ccaaatgtat taccaaattt agagagatac attttaaaag gattagaaga
   124381 gtgtaggaat tatccagata taaattatac aaacttgaga gaaaatatat caaaatatat
   124441 agatataaat ccagacttta taatacctgg caatggtgca acagaagtga tttatttgct
   124501 tatgaagagt attaaaaaaa aattggctat aataaatccg actttttcag agtatagaag
   124561 aagtgctgag ttaaataatt tagatattat agatttagag ttagatttag aaaataactt
   124621 taaacttaat atagatataa taaaagaaaa tataaaaaga tttgatagtt tatttatatg
   124681 taatcctaat aatccgagtg gtaatgtcca agatttaaag gaacttgttc atttactaga
   124741 taaacataat aaggtactaa taattgatga aactttcatg gaatttgttg aagatgaaag
   124801 taaatatagt ttggttaaat atatagaatc aaataaaaat atatttataa ttaaagctgt
   124861 gactaagttt tttggtatgc ctggtttaag gctaggatat ggtcttacaa gcaacactga
   124921 aattatgaac aaaatttatg aacacaaaga gccatggact atcaattctt ttgcagatat
   124981 actatccaat tttatttttg aagataaaga gtatattaaa aatagtaaag aatattacat
   125041 agaagaaaga aaatatatgt tacaagagtt gagaaacata agaaatataa aggtctatga
   125101 tacagatgct aattttatct tgataagaat atataaaaaa acaactaaag aattgaaaaa
   125161 agatttgttt aagcaaggaa acatattagt tagagatgca tctaatttta taggattaga
   125221 tgatagtttt ataagagtgg ctataaaatc tcatgaagat aacaaaattc ttatagaaaa
   125281 tatgaaaaat ttattgggtg attaaaatga aatcttatgg aatatgccca gcatcttgtg
   125341 gagaatttgt acaaggtata attgatgatg aagaatattt atgttcatat gcaatagata
   125401 tgtattctaa agtgtatatt gaagaaaaat tagtagatat aaatttaggg agatataagt
   125461 caaggttagc aattgaaaag gtatttgaaa aatttaattt acctaaaaaa tatactaaaa
   125521 atatttcttt aaatataaat agtaaaatac ctgttggaaa aggaatggca agttcaactg
   125581 ctgatatagg agctactata aaggcaacat tatcattgat agataaagat ttaagtagcg
   125641 aggagatttc taaattagca gcagaaatag aaccaacaga ttctatattt atagataaaa
   125701 atagtatatt taatcctcta aatggaactg ttataaaata cctaggaaat ctgaccaatg
   125761 cgaaagttgt aatacttgaa ccaaacaaag tactagatac tatgaagatt agattgaggc
   125821 aagattataa taaattaaaa gtagagaata aagaagtaat aaaaaaatca tttgctcttt
   125881 tagaagaagg attgaaaaaa aataatttat ctctagttgg agaggcttgt actttgagta
   125941 gcttagcaaa tgagaatata gaaaaaaaag agtgtttaaa tgaaataata aaaatatcaa
   126001 aaaaatatgg agcatatgga gtaaatattg ctcacagtgg aactgtagta ggtattttaa
   126061 ttgataagtc tatgaatgat aaaaagatga tagatgcctt atgtgaatct aacataaatt
   126121 ctgtctataa taaaatttat acacaaaaca taattaatgg aggaattaag ggggaaatag
   126181 aatggaatac ataaagaatc ctatgaaaat agaagaaaaa agttttgaat tgatacaaga
   126241 aataatagac gaaattagac cagattataa atttaagaat aatatcgaag aaaaaataat
   126301 aaaaagagct atacatacta ctgctgattt tgattactta gatatattaa aaatatcaga
   126361 agaagcagtt gatagtataa tagatgcatt aaaaaataat gcaagtattt atactgatac
   126421 aaatatggct cttagtggta taaataaaag aaagttagaa tcattaggat gtaagtataa
   126481 atgtttagtg gcagatgatg aaactgtaaa attagctaaa gaaaaaggaa ttactcgttc
   126541 tatggcagca gtagaaattg cagctaaaga agaaggaaga aaaatattcg ttttaggtaa
   126601 tgctccaaca gctttatata aagttatgga gatgaaatca gaaggtagat tagatttaga
   126661 tgcagttata ggagttcctg taggttttgt aggagcacaa gaatcaaaag atgaagttga
   126721 aaaaacagat ataccatata taatttctaa aggtagaaaa ggtggcagta atttagcagc
   126781 agcaatagta aatgctatat tatatactat gtaggtacct atatggaaga atatgtatat
   126841 atagatggaa aaaaatatag aagaggatat actacaggtt catgtgcaac aggtgcatct
   126901 aaggctgctg tatatatgtt gattacaaaa aatagaatca atactataaa tatagatact
   126961 cctaagggga taccattact actaaaagtt gataatataa atatttctga tacatttgtg
   127021 gaatgttcca taaaaaaaga tggtggagat gatatagatg caactcatac catggatatt
   127081 tatgcaagag ctgaaattgt agctaaaaat gataagaaca aagggtatct tactctaaag
   127141 gatatagata gtttaagcac caatagtgag tgtaaaagtg agctctataa gtttattagg
   127201 gtttatggcg gaactggtat tggtgtggtt acgaaaaaag ggcttagtgt ggatgttggt
   127261 aagcctgcta taaatccgac tccacttaaa atgataaatc atgaaataag aaagcttata
   127321 ggagataatt ttgaatctat acttggaaat gataaagttt taaaaataac aatctttgct
   127381 ccacaaggag aaactgtagc aaaaaaaaca tttaatccaa gattaggtat agttggagga
   127441 atatctataa taggtacaac tgggattgtt gaacctatga gtgatgaggg ttggaagaag
   127501 tctctatcta tagaacttca gatgaaaaaa gaacaaggct tagataaaat aatattggtt
   127561 ccaggaaatc atggagaaca gtttataaga gaaaaattaa acttagatat taagtatgta
   127621 gttagggtaa gtaattttat aggctatatg attaaagaag ctcaaagaat aggatataag
   127681 aaaatcttaa tggcaggtca tataggtaaa tttataaaag tatctgctgg tatttttaat
   127741 actcatagta aggtagcaga tgctagaagt gagatattag tggcaaactt agctttaatg
   127801 ggagctagat acgaattttt aaataaaata aatcaatgcg taactactga agaagctgta
   127861 gagctaataa ataatagtga atatagagaa gtatataata tattaagtaa taaatgtagg
   127921 gagagagtaa agcaatactt gaatgaagat tcagatgata ttgatgtgga agtaatcata
   127981 ttttcaatgg ataagtcttt attaggtaaa tcggataata cagatgattt agtggaggtc
   128041 tttatatgat aaacataata ggtctaggac ctggcaactt agactatata acaaaaaaag
   128101 gtgaaaattt aatttccact tctgatgtat taattggtgg taaaagaaat ttagagtcta
   128161 taaaaaattt tgaaggagaa aaaatagttc tggattctaa tttaagagaa attatagagt
   128221 acataaataa caataaagaa aagcaaatat caataatagc atctggggac ccattaatat
   128281 atgggatagg tagatatcta tctaaaaata ttgataataa gatgttaaac atggtttctg
   128341 ggattagttc attacagtac atattttcaa aaatatatgt agatatgaat gatgtatata
   128401 ttacaagtag tcatggcaaa gtaccagatt ttgattacat attatcacat aaaaaagtat
   128461 gtatggttac agattcaaag ataggaccaa aacaaataag tagagaaata atagatagaa
   128521 atctaaataa aattattgtt gtaggagaaa atctgtcata tgacaatgaa aaaataacaa
   128581 tagcaaaacc agaagagata ataagaatag acaattttga tatgaatgtt gtggtgattt
   128641 tagatgagga atagtgagtt tataacaggt aaagttccaa ttactaagga agaggttaga
   128701 gcaatatcaa taagtaagtt aaatttagta aatgctaaaa acctcataga cataggggct
   128761 ggtacaggaa gtgtaagtgt tgaagctgca tataattatc ctaatttaaa ggttatatct
   128821 atagagaaaa atgatgatgc tatagagctt atagagaaaa ataaaaaaaa attcaactta
   128881 aaaaatatag aagtgataaa aggatatgct ccaattaatc tagggttaaa tgttaaagtt
   128941 gagtctattt ttcttggggg aacaggaaat aatctggaag aaataataga atggtctaaa
   129001 aaaaatctcg ttacaggagg aagacttgta gctaatttta taataataga tacatttaat
   129061 caaactttaa aactgcttaa aaagcatgga tttaaagaaa tagatgtatg tgttttgaat
   129121 gtttctaaac tagagaaact aggaaaaggt gaatatttta aaccactaaa tcctatatat
   129181 ataatatctt gtgaaaaagg ggaaaatgat gatgaataaa gtacattttg taggagcagg
   129241 acctggagat aaagagctga taacattaaa aggatacaaa ttattaagta atgcagatgt
   129301 agtgatatat gcaggttcac ttgttaatcc tgaacttttg gaatactgta aagaagattg
   129361 ccaaatacat aatagtgcac atatggattt acaagagata atagatgtta tgagagaagg
   129421 tatagaaaat aataaatctg ttgtaagact gcaaacaggt gatttttcta tatatggttc
   129481 aattagagaa caagtggaag atttaaataa attgaatata gattatgact gtactccagg
   129541 agtaagttct tttttaggag cagcatcatc tttaggggtt gaatatacag ttccagaaat
   129601 ttctcaaagt gtaattataa caagaatgga aggcagaact ccggttccag agaaagaatc
   129661 aatacaatca tatgctaagc atcagacatc tatggtaata tttttatctg ttcaagaaat
   129721 tgagaaagtt gtgtctaaat tactggaagg tggatatcca aaagatactc ctatagcagt
   129781 tatatacaaa gcaacttggg cagatgaaaa aatagttaaa ggaactttaa gtgatatagc
   129841 tgtaaaagtt aaagaaaaca acataaataa gactgcttta ataatggttg ggagattttt
   129901 aggagaagag tataataatt caaagttata tgataaggat ttcaaacatg aatatagagg
   129961 gtaatattgc tataatctgt attacagaaa atggaaaaaa attagctcta aagataaatt
   130021 ctctagtaaa taactgtgtt atatatcaag taaaaaataa aaaaagtaat ttagttgttg
   130081 aagaaacatg tgtacataca gttcaaaaga agttaagtga ttttgtagga gaaatattta
   130141 gcaaatttga ttacatagta tttataatgg ctacaggtat agttgtacga agtatagcac
   130201 catacataat aagtaagttt agtgaccctg caattttggt aatggatgaa aaaggcaaaa
   130261 acgtaataag tttattgagt ggtcatattg gaggggcaaa cagcttgaca cagtacataa
   130321 gtagtcttat tgatgctaat ccagtaataa caacagctac tgatataaat caaaaagctt
   130381 ccttagatat gatagcaaaa aaactaaatg cacatattga taattttaga gaaagtgtaa
   130441 aagaagtaaa ttctatgcta gtgaataata aatgtgttgg attatatatt gatgaaggat
   130501 atcaagttga tactagggga tttaaactta tagaaagtaa ggatgagtta agagatagtt
   130561 tttcaaacac atatatagaa aaattagttg tagtaagcaa taaaataaat tgtattgaag
   130621 atattgagaa tttaaaccta gataataaat ttgaacattg ctatagtacc aaaaaaataa
   130681 taaaggtaat tccaagagat atagtgatag gaattggctg tagaagaaac acagatagtg
   130741 agctgatgta taattcactt gaagagtttc ttaataaaca aaatatagat attagagcaa
   130801 taaacacagt tggaagtata gaactgaaaa aagacgaaaa agcaataatt gaattatcaa
   130861 aaatattgaa ggtgccattt aaaacatttt cagtagatga aatatctaag gttgataatc
   130921 tttttgataa atctgatttt gttaaaaaaa atgtgggcgt gtattcagta gcagaacctg
   130981 tagcatatct tttgagcaaa ggtaatttgt tagttgaaaa acataaatat aaaggaataa
   131041 ctttttcagt ggggagaata aaaatatgat atacgttgta ggaattggac caggaagtaa
   131101 agatacaatg actttagaag caataaaagc aatagaagat tctgaggcta ttgttggata
   131161 taagacttat ataaaactaa tagaagaatt tatacaagat aaagaaataa tccaaaatgg
   131221 tatgaggcaa gaagttgata gatgtaaaca agcagtagag gaagcaaaaa aaggaaaaaa
   131281 agtagcagtt gtaagtagtg gtgatgctgg aatatatggg atggcaggtc ttattttaga
   131341 attaatatct aaagaagatg aagatataaa agtaaaggta attccaggtg ttactgcaag
   131401 tattggtgca gcagctatac ttggagctcc tattatgcat gatttctgtc atataagttt
   131461 gagtgattta atgactccgt gggaagtaat tgaaaaaaga ttgagattgg ctgctgaagc
   131521 cgattttgta atttgtttgt ataatccaag aagtaaggga agaagtgaac atctaagcaa
   131581 agcatttaaa ataatgggtg agtttaaaag tggagataca cctgttggag tggtaaaaga
   131641 tgtaggtaga gaaaaagaag aaaagcttgt atgtactttt gaaaatatgg actttgaaaa
   131701 agtcgatatg actacaatgg ttataatagg aaataagtct acctatatta atggtgaatt
   131761 gatgataact ccaagaggtt atacagtatg attttaattt taggaggaac ttcagatagt
   131821 ttatctatat gtgataagat aaatgaactg aaaaatcaac catatatcct ttcagttact
   131881 acagattatg gaagggaact tgcacaacaa catgcagaga atgtaatttt aggtaagctt
   131941 ggaaaagaag atatgctaaa atttataaaa gataataata tagtaaaaat aatagatgcc
   132001 actcatcctt atgcagttga agtatccaaa actgctatta cttgtgcaaa actattgaat
   132061 atagattata taaggtttga gagaaaatct ttaattgaag aaatagatta tgataataaa
   132121 tttatagtag atacaattga agaagcctgt gaaatagcaa ataaaatagg gacaaatata
   132181 ttcataggaa caggaagtaa aaatttgaac agatttatag aggaaataag tgataaaaat
   132241 ttagttgtta gagttcttcc aacgagtgaa gtcatattaa gttgtgaaaa attaggttta
   132301 agtgcagata atatagtagc tatgaaaggt ccatttagcc agtatataaa tgaagaaaca
   132361 tataaacatt acaatataga tttagtcata acaaaagaaa gtggaatagc tggtgggttc
   132421 ttagagaagg taaatgcatg taaaactttc aatataccag taataattat aaaaagagaa
   132481 tcgattaact acgaaaatgt atttaatgac ataaataaaa ttaaagacat acttgtgtaa
   132541 tttttaggag gagaatatat gaagaaagcc ttattagtag tgagttttgg tacaagctat
   132601 catgaaacga gagaaaagac aatagatata tgtgaagata aaataaaaaa ttcgttaaaa
   132661 agccatgatt tttttagagc ttatacatca aatatgataa taaataaaat aaaaaaaagg
   132721 gatggaatag aaatagataa tccaatacag gctttagata aaatatatga acaaggatat
   132781 gatgaagtaa taatccaaac acttcatatt atatgtggcg aagaatttaa caaattaaaa
   132841 gaacaagtag atggatattc ttctaaattc aaaaagattg tattaggaag acctttgctt
   132901 acacatattg aagattatca ggaagctgta gaggcaatta agcatcaaat tcctcatatg
   132961 gaaagtaatg aagcagtagt atttatggga catggaacac ttcatgaatc acattcagcg
   133021 tatccagcat tggaatacat gcttagggat aatggaataa atgcttatgt tggtacagtt
   133081 gaagggtatc cagaaataga acatgtaata agaagattaa aagaaggaaa tataaaaact
   133141 gtaaatttga tgccatttat gttagttgca ggagaccatg ctataaatga tatggcagga
   133201 gatgaagaag attcttggaa aacaatatta gaagaaaatg gatttaacgt aagagttcat
   133261 ttaaaaggac taggagaaaa ttcttatata caagataaat ttgttcgtca tgctgtaaaa
   133321 tgtgcagaga atgcgaagtt ctatggtata ggagcaggac caggagatgg ttctttactt
   133381 acgataaaag cggttaatac tttaaagaaa ctggatattc tatacactcc agaatcaaaa
   133441 aagggtggag atagtctagc tttatcaata gttagtgaat atttacctga atcagtggaa
   133501 ataaagtcta ggcatttccc aatgagtttt gatgggaatg aaaaaagttt agcttgggat
   133561 aatgtggcac aagaaattat atcagatgtt aatgatggta aaaatgtagg atttgttaca
   133621 ttaggagacc ctatgattta tagtacatat gtatatataa tgaaaagaat attaggagag
   133681 gtagaagtcg aaactatacc aggaatttca tcattttcca atatagcatc taatcagaat
   133741 tttccattag tcatggataa agaagcttta gtggtaattc cttgtactat ggaagatgat
   133801 aagatagagt atgctttgca aaattataat tcaatagtat tgatgaaagt atataaaaat
   133861 tttaaagaaa taataaaaaa attagaaaag tatgatttaa tagaacatgc tattttagta
   133921 agtaattctt cccaagaaag cgaaaatgtg tttacagatt taaaagaagc gcaccttgaa
   133981 gataagatat cttatttttc tactatacta gtaaataaag ataataaaat aaaataggtg
   134041 aaagcaatat ttaaaggaga cttaatatga atatagtggt tggaactagg ggtagtaatc
   134101 tagcgcttat acaaacagaa tgggtaataa atgaattaaa aaagaagtat ccagaaatta
   134161 gttttgagat taaaatcata aagacaaaag gagatttaat tcaaaatgtt tcactggata
   134221 aaataggtga taaaggattg tttgtcaaag aaatagagca acaattatta gatggaaaaa
   134281 tagacatagc agtacatagt atgaaagata tgccttctta tttagcagat ggactaaaat
   134341 ttgctcatac gcctaagaga gaagacccaa gagatgttct aatacttaga gaaggatata
   134401 aaaatttaga tgatttacct catggagcag taataggaac aggaagtaaa agaaggaagt
   134461 ttcaattatt gaaacaaaga cctgatttaa atatagtaca agttagaggt aatgtggaaa
   134521 ctaggatacg aaaaataaaa gatgaaaata tgcatggtat tgtgttggca gcatcaggaa
   134581 taattagagc taatttgcaa gataaaataa gttcttattt acctgttgat gttgttattc
   134641 cagcacctgc ccaaggagct ttagctatag aaattagaag caatgatagt acgatagagg
   134701 gaatagtaaa ttcactgaag gatgagaata cagaaatcca aatattggct gaaagaggtt
   134761 ttttagatgg tgtaaatgga agttgtcata ttccaatggc agcttattgt gaaataatcc
   134821 aagataaaat acatcttact ggcttatatg gagattcaga aggaaaaaaa gtagtaatca
   134881 agtctataga tggagatatt tcttctccta gagagttagg tttaaagtta gctaaacttg
   134941 tattgaagga gtatgagaat tatgaagggt aaggtttact tagtaggggc aggaccaggt
   135001 gattataaac tcatgacttt aaaaggttta gagtgtataa gaaaatcgga tgtaatagta
   135061 tatgatagat tagcaaatag tagttattta agagaagcta agcctgattg tgaacttata
   135121 tatgtaggca aggcatcaag taatcatatt ttgccacaag aagatataaa tagaattata
   135181 gcagaaaaag ctaaagaagg aaaaattgta actcgtctta aaggaggaga cccttatgta
   135241 tttggcagag ggggagaaga agcagagact ttagtagatg aaggtataga atttgaagtg
   135301 gttccaggta taacttctgc tataggaggt ttatgttatg cgggtattcc tataacacat
   135361 agagaccatg cttcgtcatt tcatgtaata acaggtcatt tgaagggtga tgatagtgga
   135421 gaattaaact ggaatgctct tgcaaataac aaaggtactc ttgtgttttt gatgggaatt
   135481 tcaaacctag agaaaataag tgaaaactta atgaaagaag gaaaagataa ggatacacct
   135541 gttgctctta taagttgggc aactagatat aatcaaagag ttgttacatc tacacttgaa
   135601 aatgtttatg aaactgctat taaagaagaa gtaaaaccgc caactcttat agtagttggg
   135661 agtgttgtag gacttagaga aaagttgaac ttctttgaaa gtaagccttt atttggaaaa
   135721 agtattgctg taactaggtc tagaaatcaa aatagtgtat tggtagaaaa aataatggat
   135781 ttaggtggaa atcctataga aatacctact attaaggtag aaaaaataca aaataatatt
   135841 aacttagaaa atgaaataaa aaatataaat aagtataatt atctaatact aactagtaaa
   135901 aatgccgtag aaatcttctt tgaaaagata tatgaaatga attttgattt aaggatatta
   135961 tctaatttaa aggtatgtgc tataggttct gctacatcaa atgagttgaa aaaaagagga
   136021 attatagcgg atatagtacc aaaaaaattt gtagcagagt cactgtatga agagttagcg
   136081 cctattttaa atgatgacga taatatactt atacctagag cagaaaatgc tagagattat
   136141 ctggttgaca aacttaaggc tatttgtgaa gtaacagaag tacatatata tagaacagta
   136201 atagatgagg agaaaaaagg tgagatatta gatattttaa attctaatga catagattat
   136261 ataacattta ctagttcctc aacagtaaat aatcttgttg aaattatagg aaaagaaaat
   136321 attaaaatat tagaaaaaat aaaaacacta tctataggtc ctataactac agagacaata
   136381 aatagtttgg gaataaaatt gtacaaagaa tctgctacat ctactataga ttcgttagta
   136441 gatttaatta taaaaaatta attttggagg cttgaatatg ttaagaagac caagaagact
   136501 aagagcaagt aaagcaatca gaaatttggt aagagaaact aaggtgaatg tagaagactt
   136561 aatatatcca ctgtttgtag tagaggggga aaatataaaa gaagaaatta aatctttacc
   136621 agatgtctat catttatcaa tagatatgct agaagacgaa ataaaagaaa taagtgagtt
   136681 gggaattgaa catataatgt tatttggtgt tccagatgaa aaagatgagt gtgcttcaca
   136741 agcttttaat gataatggaa tagttcaaaa ggcaattaga aaggtaaaag aaataaattc
   136801 agatataaat gtaataacag atgtctgtat gtgccaatat acaagtcatg gacattgtgg
   136861 gattttaact gatactggtt atgttgataa tgataaatca ttggagtatt tggctaaaat
   136921 atctgtaagc catgctaaag caggagctga tatggttgct ccatctgata tgatggatgg
   136981 aagaatacaa gcaataagag aagctttaga tgaaaatgga ttagaaaatg ttggaatcat
   137041 ggcttatagt gttaagtatg cttcaaatta ttatggacct tttagagagg cagctcattc
   137101 agcaccatct tttggagata gaaaaacata tcaaatggac ccagcaaata gcaatgaagc
   137161 tataatagag actgaacttg atatattgga aggtgcagat atacttatgg ttaaacctgc
   137221 attatcatat ttagatatta taagaagagt taaagataat tttgacttac ctctagcagc
   137281 ttataatgta agtggagaat actctatgct taagtttgct gtgaaggaag gtttattaaa
   137341 tgaagatgta attcttgaat caattacatc tataaaaaga gcaggagcag atataataat
   137401 aacttatttt gctaaagaca ttgctaaact gttgaaaaaa taaattctag tagtataaag
   137461 aatatcaaaa agtataggaa ttgtaattaa ctattataca gtagttttgt ttagacattt
   137521 attgaagaat aatagaaact aatttgcaat ttctatactt tatttatgta actaaataaa
   137581 atttggaggt agaagatgct atatcctatt aatttaaaat tagatgagtt agatgtagtt
   137641 ataattggtg gtggagaagt tgcatatagg aaatgtaaaa attttttaga gtttaacaaa
   137701 aatgttacta tagtttctaa acaaatttta aataaatttt atgatttaaa aggaaatata
   137761 aaaataataa aagatgatta taaagaaata tatataaaag atgcttctgt aataattgct
   137821 gccacaaata atagagagtt aaatatggaa ataggattat attgtaaagc aaaaaataag
   137881 ctagtgaatg tagttgataa tatagaaata tcgaacttta ctgttccatc atatataaaa
   137941 agaggagatt tacttataag tgtgtctact gggggcaaga gtccttcatt atcatcaaag
   138001 ataaaaaaag aaattgaaga gagatatact gaagattatg aggagtattt aaatgtatta
   138061 ggagatataa gaaaaaaggt tataaaaaaa tacgaagata aaagtaaaag aaaagatgtg
   138121 cttaatatgt tggtaacact tgacctagaa gaacttaaga agtttgatat ataaaaaata
   138181 aaataaaaaa tgttaaaaag gtgttgacgg attattttta ag
//
LOCUS       DAMJXI010000004       128030 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.004, whole genome shotgun sequence.
ACCESSION   DAMJXI010000004 DAMJXI010000000
VERSION     DAMJXI010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 128030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 128030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..128030
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.004"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(<1..1899)
                     /locus_tag="PC465_000431"
     CDS             complement(<1..1899)
                     /locus_tag="PC465_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein CwpV"
                     /protein_id="HDF2647765.1"
                     /translation="MKIPKKIAAMLTVTMIAGSSTAGIASAQTVATNLTGQERYETAV
                     KISQDGWKNADEVVIVNDSSIADALSATPFAKAKNAPILLTSKDKLNDKTKAEIQRLK
                     AKKVYLIGGTSVLSTNIEKEIKDLKISFERISGAERYQTSLELAKKLDAISDVKKIAV
                     VNGEKGLADAVSVGAPAAQNNMPVILADSKNGTAVADKFIKDAGITQSYVVGGESSIS
                     EAVKNKLPNSTRLGGTDRNDTNAKVIKEFYKKTDLKNAYVTKDGMNKQDQLIDALAVG
                     VLGAKNQSPVVLVGKNLSASQKSLVNSKSFDKITKVGGNGNETAFNEMKSLQEVKTVE
                     AKTISELKSAIDKATANDVINFKPTSEVKEAFTIQTDKAVTVNLNGTYTKTVTINMPN
                     GDVNNYAKVDDVVIDDVKDGTFVNYGKITNLKVNDKNGAKIENNSKGEIGSLTVASGA
                     SQVKVTNGGKITTVTNNSKGTTIDNKGTISSVKGDNSPTISGNSPSSNSSGGSSSSGG
                     SSGGSSGGSSSSKVGQIKFSATDKQIKMASGDKTVDPSDNTYILKLTNGTVKDGDVKA
                     NVKVAGLPSGLDYTAVGNRSANTITITVSGTASQSIQNDLNNVSVLVKAGAVSGTGAT
                     DSIANTTFE"
     gene            complement(2897..4036)
                     /locus_tag="PC465_000432"
     CDS             complement(2897..4036)
                     /locus_tag="PC465_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDF2647766.1"
                     /translation="MVIKLTIEEYKNKYFTGNKIVLSINSFDNKELYYHETENILNLI
                     NEIDKLTSSKIFKIIEDKNDLALESYYSSVIEGAFSNRKIAKSIIRGKMKPSNKSEYM
                     IYNNHRALEYGLDNLDKLYSHKFIYDLHHILGENCLDSEEYEYRTEKVYVCDSKGEII
                     HIGLEPLKIYDFMSKLIDFMENSKVSNLIKSAIIHFYFVYVHPFSDGNGRTSRALSYL
                     YLIDKGYDTFKEFSISYMISKNRTKYYKAILDVENKGNNLTVFIEFMLKSIIQSINEM
                     RNMHDRKSLESILKEELFENDITLSATEEHILKYICNKDNYSMTLENYIKKNKSRYLK
                     AGIKEIELVDQLMEVFNNLEGIEILSKEKNIYKVNDKYLKMLDID"
     gene            complement(4573..5412)
                     /locus_tag="PC465_000433"
     CDS             complement(4573..5412)
                     /locus_tag="PC465_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2647767.1"
                     /translation="MSDIKNEVSKKTLSKKDVIKSWLRWFFFAQSNYNYERLQSTAFS
                     HSMLPVLKKLYPDKDELKQEVETHLAFFNTEPICGCVIHGITIAMEEEKANGADEISG
                     DGMNAIKTGLMGPLAGIGDTLTQGVITPIVLAVCIGLTEGGASIAGPILFVIAQYIIM
                     TSISFGMWTNGYKYGKKAVESILQGGIVNKVIEGASILGTLVMGGLVGRFINLSTPIS
                     YTSGDFKFSLQTDLLDKIFPGLIPLVLTLLVLFALKKGLSPIKIMFILIVVGAITGIL
                     GLF"
     gene            complement(5436..6194)
                     /locus_tag="PC465_000434"
     CDS             complement(5436..6194)
                     /locus_tag="PC465_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2647768.1"
                     /translation="MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGII
                     LGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAV
                     PLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
                     VVYFGPNAIDGMLEVMNDNVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILM
                     AVYFKVDIIVISVIGVILALTITSIKYGKDSATS"
     gene            complement(6241..6714)
                     /locus_tag="PC465_000435"
     CDS             complement(6241..6714)
                     /locus_tag="PC465_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2647769.1"
                     /translation="MSNIALTRIDDRLIHGQVITAWCKITSAKRIIIVDDLVVKDPFI
                     VQVLQMAAPSTVKVEVHDVESGAEVLKSHNGDENLIVLVKYPKTVLGLVNSGVDLKEL
                     NVGGMGAGLGRKSFYKNISVSDEEKEIFRELISKDVKCFIQIVPDAKKIDVGTLL"
     gene            complement(6743..7159)
                     /locus_tag="PC465_000436"
     CDS             complement(6743..7159)
                     /locus_tag="PC465_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2647770.1"
                     /translation="MIHMAGIIIATHGNMAKAMLESAELIVGKQENVETLGLNHGDSI
                     DEFSRKLEDGIEKYKDEGVLVLLDFYGGTPFNTSAIIINKFAKVCELECLTGVNLPML
                     LELFLNRDTMKLKDLKNLCEEVGISGIKDVKTVLKL"
     gene            complement(7206..8258)
                     /locus_tag="PC465_000437"
     CDS             complement(7206..8258)
                     /locus_tag="PC465_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF2647771.1"
                     /translation="MKSVRFYGIRDLRVEDVDVPKILEKDDVIIKVKVAGICGSDISK
                     YSKTGPHMVGEILGHEFSGEVAQVGKEVRSFKIGDRVAVCPAMPCFECDECKKGLYSR
                     CNNVAIIGNKELGGCFAEYTKVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAK
                     VGDTVVVLGTGPIGLFSIQWAKIFGSTKVIAVDVFDEKLDLAKELGADICINAKEKNI
                     VEEIKRLTDGDGADIVIESAGTPLTCGQVLLLAKKGGTVLYAGVPYGDVALTREQFEK
                     IVRSELTVKGIWFGNSFPFPGKEWSAGLYHMQKGDMNVEKLVTHRINLEEVPAYFEKV
                     YKRDIFFGKIMINIDN"
     gene            8654..9334
                     /locus_tag="PC465_000438"
     CDS             8654..9334
                     /locus_tag="PC465_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDF2647772.1"
                     /translation="MKKVYQGKTKDVFELDNGNYLLKFKDDVTGKDGVFDPGENSVGL
                     SIDGIGRANLETSVKFFEILNNAGIKTHYVSANLEEATMEVLPAKVFGNGLEVICRYR
                     AVGSFLRRYGSCVEEGAKLDCYVEATLKDDDRCDPLITSEGLEALNIMTQAQFDSMKS
                     MTQKISNIVRDTIAEKGLELYDIKFEFGFYNDEVILIDEIASGNMRVYKDGVIVDPMD
                     LTALLLDK"
     gene            complement(9467..9787)
                     /gene="sugE"
                     /locus_tag="PC465_000439"
     CDS             complement(9467..9787)
                     /gene="sugE"
                     /locus_tag="PC465_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000118520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HDF2647773.1"
                     /translation="MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFY
                     FLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKL
                     LSTN"
     gene            10169..10996
                     /locus_tag="PC465_000440"
     CDS             10169..10996
                     /locus_tag="PC465_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HDF2647774.1"
                     /translation="MNFYKIAVCQMITTENKIENINHAVDMVTEAAINGAKIVVLPEM
                     FNCPYENKYFPKFAEEYPGETTTILSKLAEKHGIYLVSGSIPELEDGKIYNTCYVFDK
                     NGALIGKHRKMHLFDIEVTGKVSFKESDTLTAGNDVTVIDTEYGKVGIAICYDIRFPE
                     LSRLMALKGAEIVILPAAFNMTTGPAHWELSIRMRALDNQIFYVGAAPARNMNASYIA
                     FGNSRISDPWGRIIAQADEKECIIYADIDRDLIPDIRQQLPLLKHRRTDLYELNTLK"
     gene            11818..12492
                     /locus_tag="PC465_000441"
     CDS             11818..12492
                     /locus_tag="PC465_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2647775.1"
                     /translation="MNNKILVVDDEEGIITLLKDYFEMNGYEVYTAQSGKDALKKISK
                     NPDIILLDINMPEIDGIEVCNRIRDYVSCPILFLTARIENTDKINGFRAGADDYIVKP
                     FDLDELGARVSAHLRREQRKSNQTKIKFYNDLTIDYEKRLICIYNNQISLSKKEFDIV
                     ELLSMNPGQVFDKEKIYDRVWGYNSNGNSDVIMEHIRKIRIKLSKHTLENYIETVWGV
                     GYKWIK"
     gene            12480..13640
                     /locus_tag="PC465_000442"
     CDS             12480..13640
                     /locus_tag="PC465_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2647776.1"
                     /translation="MDKINNMSLKKAFFVLTLSSLIIASVLTTFAYILLNNLYNSIQD
                     KYLKTPINTGIITIVQNNVNQFSDYDKTLLNIINILQLVLPLIFFIGLLLLADIIFYK
                     VKLKTPIEILNKGAMEISNNNLDFCLEYNNNDELGNLCNAFEKMRSELNKNNIKMWTM
                     INDRKQLNAAFSHDLRNPLTVLKGYSNYLTKYIPTGKLSDEKILSTTQLMSEHINRIE
                     YYVENMSNAQRLEDLVVSKSMSNINKFIENLDENISIIAKQEGKSFTLKNQINNINLF
                     FDENIILRVVENIISNAFRYARNNVSILIYLEQELLTFVIEDDGIGFSKESLKLALRP
                     FYRDKTLNDSNAHFGMGLYISKILCEKHGGSISIENNSTNSAKITAKFSTRN"
     gene            13857..14384
                     /locus_tag="PC465_000443"
     CDS             13857..14384
                     /locus_tag="PC465_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014118918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HDF2647777.1"
                     /translation="MKSFANNITFSRIVFALLMLSSTFCSLPFWICYFWCGISDILDG
                     LIARKLRQQSGIGAKLDSIADFIFAVTILVTVGKNIALPMYLWWCIVAIALLRLISYS
                     IGFFKYRTFSSLHTLMNKITGISIFAFPLLYICFGLDVAGIMICIVAFLSSFEEIAIM
                     IKSKELNRDIKSIFM"
     gene            14670..15338
                     /locus_tag="PC465_000444"
     CDS             14670..15338
                     /locus_tag="PC465_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2647778.1"
                     /translation="MIIKAKQLSKIYGSNNNKVIALNNVNLEINSGEFVSVIGPSGSG
                     KSTLLHILSGLDNPTSGQVLLDDKDIYKHTEKELSALRRKSFGFVFQQFNLLPVLTAS
                     ENISMPVLLDKKQPDKGYLNEISSLLGIADRLNHLPHELSGGQQQRVAIARALIAKPD
                     IIFADEPTGNLDSKSGSEVMNLLIKTSKQFGKTLVVITHDDRIAKLADRKISIIDGVL
                     MEVK"
     gene            15341..17809
                     /locus_tag="PC465_000445"
     CDS             15341..17809
                     /locus_tag="PC465_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2647779.1"
                     /translation="MKNYLSLSIKELKSQKLMTTFIIIAIVLSTIMTTVVGQSIGILQ
                     NLRIEQARSFNGDRHVSFHQLTKNQVDDIKKDDRVYQAGTSITIGSSKIKDSGISVLV
                     KEYDKTGLSNYPKLMKLKSGHLPKDKNEIALDENTLKLMGIKPRLGVTIPMNLDISLL
                     NDTIPPYNYTANFKLSGILEDDYTGYVSGIVNGIVGKGTSENLLPKRYILSSLDFKIK
                     QQEKFQEIVNQLAKKINLSHNSIQYNWIYLNALKIQFEKDENSSNSDGISMIILVSLF
                     VALLVLLASGLVIYNILKISVTKKIKEYGCLRAIGAEPNQIYKIVILQILILCTVAIP
                     IGAVIGIISSKGITGMVTNILNPDILLANDNKEITELIHKNTTAYMFPLVLSTNVSLI
                     FSFISALPSAIYASHVSPKIAMVGSTTKIKRKIKREKTIKNFERHLAWLNLKRNKGRT
                     IITILSLFMSITVFVALSEFSNVLDVSRSVSNLKEGDFSLTNEISGFDKSTLDKITKM
                     KNVNRTSFIKYSEYKQGEIDTDINFENSGEMLKIIGIDEQTLKDLMPSITDSILEDFK
                     NGSICFIKNPIAISTPGVKTRHTNLKPKDSITINKKQLDIYSTVDKMFFLQGNGWING
                     VDVIVYDSVYNTLTNKNKFNQINIYAKDKSKLEQIGLSIEQICENNPGSHWISYIESD
                     KQLKESFKQIEFLAWAVILFVGLIGTLNIINTTHTNINTRTNEIGVKRAIGMSNSSLY
                     KMFLWEGVYYGIFAAIFGSIAGYASAIIINMATIEKLDFTNIPITSILQATIISVLAC
                     IIATLIPLRKVKKMNIIDCIDINL"
     gene            complement(18049..19473)
                     /locus_tag="PC465_000446"
     CDS             complement(18049..19473)
                     /locus_tag="PC465_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2647780.1"
                     /translation="MKNQSLITQFRHTFIFIIIASIVATVITYVFALYLYIHSLNKDI
                     YPPNYYERQVPRIEKYINEKNIALLSQSNEEGLKRTIRGDDMLYQVVDNNGNILYGTN
                     PKKLFKTKEELFNNNINKTVRKGGYIHTVPIKGDNGKIEGAVILFYQVKITFANIRGR
                     FVFAVIIMALFSPFLYIVGFTRWLSKRFVKNINQPLHLLIDASKKIKEKDLDFEIDYY
                     SDNELGKLCSAFSEMKDELKGSLSAQWKMEQERVEMVEALAHDLKSPLSIILGYTDAL
                     IGNNTDDNEKLHRYLTVIRENTEKSAALVQKMQYTSDLEKSNIQLNLVPINLPEFLRQ
                     KVQDYELQAHQKEVELILKMQGNIQSPIQIDVDRLTRIFDNIISNSLQYTPSGGNISI
                     TVKDEKNCISYEICDSGRGFSSKDLKKALDKFYRGDEARQTKGGHSGLGLYIVKQLVE
                     QLGGSVKIENSKSGGACVKFWHSI"
     gene            complement(19492..20184)
                     /locus_tag="PC465_000447"
     CDS             complement(19492..20184)
                     /locus_tag="PC465_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2647781.1"
                     /translation="MSKILIIDDEMDLVMLLEDELKAKGHEVLIAYDGQAGIELSKQE
                     PDLIILDIMMPKMNGFEVCQAIRDDVLCPIIFLSAKQSETDKIKGLTFGGDDYVTKPF
                     GLRELMARIEANLRREKRSQYINEENKRSTLYFGKLCLYMKERAIKIDGKNIDLTKIE
                     YDIVELLALHAGQVFSREQIYEKVWGCDSEGDSSTVVERVKKIRAKFSAVTPEKEYIS
                     TVWGIGYKWNKM"
     gene            complement(20236..21015)
                     /locus_tag="PC465_000448"
     CDS             complement(20236..21015)
                     /locus_tag="PC465_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HDF2647782.1"
                     /translation="MIKLLSSEWLRAKRTAVQWLTLCMPIIFSLCVVFYLTTKSGSTQ
                     EFAFEGFFTVWTVFIIPIGVGILAGFIVQEEELAGNFNGFLCVGISRVRLYLGKFLFL
                     LFCLTICTFIATLILCIGMSIAVPSGATIWLFLSAAGLVVIGTLPLLAIHLWVSFAWG
                     MGASIGISIGGILMAAILGLTSVGEKVWAFVPWTWPVKLGMLPGIYFIKEAGTISTEA
                     FYSKVMQTASIELIVVAIGLIIFLIGGVIWFKMWEGRKSYE"
     gene            complement(21012..21782)
                     /locus_tag="PC465_000449"
     CDS             complement(21012..21782)
                     /locus_tag="PC465_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HDF2647783.1"
                     /translation="MNALQSELLKYKRTFMGKLIVFFPVSFAAYAFIMQSTLMQNPLS
                     QTTSWAWQNLLALIFNWWSFLFLPIGFALFATLVAFQEKKAGNYRALRTHNVSPMTLW
                     INKVIAMAVYSFISTLVLIVVTIITGLILKAGPVPFGQIIGASIVCWVVSLAILPLQL
                     WLATWKGMFLSMGVGALGMIFGVLAATKPFWIAVPWSWAVRMVCPIINIHPNGTILEA
                     GDPLLNTSVIPIGIVVSLVVFIVLTALTAAWFNRRDDK"
     gene            complement(21779..22483)
                     /locus_tag="PC465_000450"
     CDS             complement(21779..22483)
                     /locus_tag="PC465_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF2647784.1"
                     /translation="MKDLILETKNLSKRYGEQMAVNNVSLQIERNSIYGLLGPNGAGK
                     STTLKMLVGLLRPTNGRIIFDRKPWKRESLAKIGSLIESPALYGNLTAEENLLVHTKI
                     LGIPKDKIYEVLEIVNLKNTGKKRASQFSMGMKQRLGIAIALLSDPELLILDEPTNGL
                     DPFGIQELRELIASFPKKGITVILSSHILSEVAQVVDNIGIINGGRLLFQGMPDPNEN
                     LEEFFTDVILKGGQNR"
     gene            complement(22738..23250)
                     /locus_tag="PC465_000451"
     CDS             complement(22738..23250)
                     /locus_tag="PC465_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647785.1"
                     /translation="MKKISQEKISTHIQEIPQEKIEQWKSLYEKYKSILKVNSKSVLE
                     IIEFLKRKYVIVEETSEEFKHVVINNIKLNKPFSQKISSDKELKPIVFTIPNEGNAKK
                     LYDTQEEIYSGCKIIVGMEFETGYVFVEGSDELNDEITSFKGLDKYDINNYYLVANYI
                     RCLKKYKLID"
     gene            23576..23833
                     /locus_tag="PC465_000452"
     CDS             23576..23833
                     /locus_tag="PC465_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647786.1"
                     /translation="MILNRAELFRGYSLNRFNEICNILSVNKIKYKYKVKNNAYSKKP
                     FFNEITLGNLGQKEDFSYEYLIYVHKDDYEQAESLINSKLR"
     gene            23976..24602
                     /locus_tag="PC465_000453"
     CDS             23976..24602
                     /locus_tag="PC465_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HDF2647787.1"
                     /translation="MKINIKSKLSEFIKQNNLFDDSRIISYLPNITIETDKIKTIMIN
                     EVVPTNTNDDFYSVDKDADYLKTTIPLFDSAGIKVSNINDILDMGIYITNAVKLPKSE
                     YTITRDTIKLHMPILEEEIKLFKNLEVVMLMGDVAKKSFNMITKKHIKKNVIPSISTY
                     KLRNNELYYDNLRVFPSYIMTGGNILIEKSKFEMASEDIKKMFEIING"
     gene            complement(24848..25627)
                     /locus_tag="PC465_000454"
     CDS             complement(24848..25627)
                     /locus_tag="PC465_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901940.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HDF2647788.1"
                     /translation="MNSKIYYFSGTGNSLVVSNILKETLNGSKEVIPLAIHRKENNID
                     INEDILVIVFPVYFADVPDIVKSFVEKLNFNINTHIYAIATCNGVAGHSLFTIDKLLK
                     KRGKKLSAGFLINMPGNALITPPDVEEERLKNQTNRVAEIAKCINNLEIGNIEGKNNL
                     KSHIDSVVLRLVGKNMQIATTKFFAENKCNGCGTCKRVCPVENISIVDKKPKWGNECE
                     RCLACFHWCPKEAINVKKSFLTNRKKYHHPDITVKDIFLDK"
     gene            complement(25695..26156)
                     /locus_tag="PC465_000455"
     CDS             complement(25695..26156)
                     /locus_tag="PC465_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2647789.1"
                     /translation="MGGARDYLNGGKMKDFEKLYEATTKLVSTSLKVKDDLKKMFKQN
                     GYDITTDHYALLRFLWEQDGISQIDLCEKSCKDKSNTTRILDVMKNKGLIVRKVDVKD
                     RRKFQIFLTDLGRELEEPLNEIASIYATETFKSISDEELPLFTDILDRIGK"
     gene            complement(26132..26809)
                     /locus_tag="PC465_000456"
     CDS             complement(26132..26809)
                     /locus_tag="PC465_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2647790.1"
                     /translation="MIITVINGSPRKNGATSKVLTYLYKDIERLIPDVKINYFDLSKV
                     NPSYCIGCLNCYKMGKCINQNDKVEYIHDIITKSDGVIFGSPTYGSSVTGLFKVFTDR
                     AHMMLERLLYRKPCIAVTTYENARGSKAISFIKSMVLDSGGYVCGSLSIKTGFNQNPI
                     TEKVESKIQKVSKKFIYCIEEKKNPPVLSQIYNFIAINAVLKPMAFKDIEQYKGIIDR
                     WEEQGII"
     gene            27042..27428
                     /locus_tag="PC465_000457"
     CDS             27042..27428
                     /locus_tag="PC465_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2647791.1"
                     /translation="MKKLPHISEAEYQVMKIIWKYAPISTTEVIEKLVETSTWSPKTI
                     QTMLLRLVKKGALTYEKNSRVFVYTPLVKEEEYVAKESSSFLNRFYNGTLNSMVLNFL
                     ENDKLSEDDIEELREILNKRTTKGDK"
     gene            27431..29230
                     /locus_tag="PC465_000458"
     CDS             27431..29230
                     /locus_tag="PC465_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaR1 family beta-lactam sensor/signal
                     transducer"
                     /protein_id="HDF2647792.1"
                     /translation="MYAPFFIRFLLSTLTLSILIAVILLAKKVFKKHISAKYQYNIGF
                     ILLIMLIIPFVPLKYINLGNVFNYLYTFNQLGSSTNRTSMIKNSPNSIINNSNALNDF
                     SVSLNQVNFDSLNILLLISWIIGILIMIAITIHCNIKIKNMKKSIQILRDEEIVFIFE
                     KCKKDIGINKDFILCKSPIINTPITFGYFKPHIILPDKSISKLSLKDIKYILLHELQH
                     FKNKDILINYIMCFLQILYWFNPLVWYAFKEMRIDREIACDISVLKKLDKDSHIEYGQ
                     TLINFVDNISRPSNLTLTSDIGGSKKQIKKRLLKIMDFHNESNTLKFKSILIFTLIAL
                     IVFGNIPKLSIMADINEKYRPTNEQTVYEDLSQYFKGFDGSFVMYDLKSKQYHIYNKE
                     KSKTRISPNSTYKIYSALLGLENGIITRNNSHIPWDGKHHSNSSWNEDQDLFSAMENS
                     VNWYFQTLDKKTGLKNIQTYLRQIGYGNYDVSGGISNFWLESSLKISPIEQVELLESF
                     YTNKFKFEDKNIETVKDSLLISKKDGVSLFGKTGTANINGKDVNGWFIGYVEKNENTY
                     FFATNIQSKDYSNGSSASKITLSILNDKKIYNP"
     gene            complement(29583..31670)
                     /locus_tag="PC465_000459"
     CDS             complement(29583..31670)
                     /locus_tag="PC465_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HDF2647793.1"
                     /translation="MIKVVYMRKNKKTRKMIIFGFLMCLLIVIIVFLAKFILDGLNKN
                     KPDEVFKQYMSFANKKQYEKMYDLLDEKSKSENKKEDFVLRNKKIYEGIDAHDISIKI
                     NDIKKNKNNDKVINYDSKMDTLAGEISFSNEVLLTRDRQKNYKIKWQSNVIFPELEED
                     NTVRVSKLKGKRGRILDRNGVMIAGQGLASMIGLVPGKMSDNIEDLKKLSTLLNVSVE
                     QIEKKLNASWVKENSMVPIKTIEKIKENTDGTVKEEDKELQESLLSIPGVKISNTEVR
                     VYPFGEKTGHLTGYVQNVNADILKEKEGKRYNDNSIIGKIGLENLLEDRIRGIDGYEI
                     IIADRYGDKKETLVTEPKVDGEDVKLTIDSKLQSKLYDQMKNDKGCAVVMNPKTGEVL
                     SLVSSPSYNPNEFILGMSEDRWNELNKNENKPMYNRFKARLCPGSSFKPVTAGIGITT
                     GKINPNENFGHSSLSWQKDSSWGSYKVTTLKDYGNTANMKNALIYSDNIYFAKAALKI
                     GEDVLAKELLKLGFDESMPFEFGLSSSKFGTDNKFETEIQLADTGYGQGKLLVNPVHT
                     ASIYSAFVNDGDMIKPHLEFKKAEFWKKGVFSKEAVKIIRDDLLQVVESPDGTGHSAM
                     IKGISIAGKTGTAEIKASKDDVTGTELGWFNAFTVDENSDKQYIVIAMIEDVKSRGGS
                     HYVIPIVKSVFED"
     gene            32031..32609
                     /locus_tag="PC465_000460"
     CDS             32031..32609
                     /locus_tag="PC465_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HDF2647794.1"
                     /translation="MPTKGEQTKQFIIDTSIMLFSEKGYSNVTMKDICEACNLSRGGL
                     YRHFNSPKEIFISILNTHKYYSQNLLDKGIKENISAKHMLEYFFQQQKADINGKYCGF
                     DFAIHEFAFVEKDQRDYMNKRYSSAITMLSNLIDYGQSKSEFKKCDSKSVAIHIMFLF
                     DSMKTSASILKLTNKDIDNQINIIKDMVILYE"
     gene            32602..33261
                     /locus_tag="PC465_000461"
     CDS             32602..33261
                     /locus_tag="PC465_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloramphenicol acetyltransferase CAT"
                     /protein_id="HDF2647795.1"
                     /translation="MNKQKFHKINLQNWERYTHFYYFSKMTNVGFNLTIEIDITNLLK
                     ETKKRNIKFYPAYLYTITTCLNRYRELKIAYDEDELGYWNTLTPLYAIFHDDNKTFSS
                     IWTEYDENFSIFYENYLADVKEYGKNHGFLAKPNPPRNCYTVSCLPWISFKSFTVHNH
                     GLENYFFPTIEAGKYYQKDEKILLPLSITVHHATTDGYHVSCFIDYIQKMCFNTKIWL
                     H"
     gene            complement(33472..35346)
                     /locus_tag="PC465_000462"
     CDS             complement(33472..35346)
                     /locus_tag="PC465_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2647796.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMIKDRETINDKK
                     VEKVNEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVFSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDVA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
     gene            complement(35351..37015)
                     /locus_tag="PC465_000463"
     CDS             complement(35351..37015)
                     /locus_tag="PC465_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDF2647797.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDEGYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESEDVIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVCLKPFHAVLLKAR"
     gene            complement(37029..37850)
                     /locus_tag="PC465_000464"
     CDS             complement(37029..37850)
                     /locus_tag="PC465_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2647798.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKKREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            complement(37949..38713)
                     /locus_tag="PC465_000465"
     CDS             complement(37949..38713)
                     /locus_tag="PC465_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2647799.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVIDDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            complement(38710..39459)
                     /locus_tag="PC465_000466"
     CDS             complement(38710..39459)
                     /locus_tag="PC465_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2647800.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KSDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            complement(39963..40568)
                     /locus_tag="PC465_000467"
     CDS             complement(39963..40568)
                     /locus_tag="PC465_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2647801.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMMKSIRELDNLKYEWICMSHGTPCIK"
     gene            40747..41385
                     /locus_tag="PC465_000468"
     CDS             40747..41385
                     /locus_tag="PC465_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2647802.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVIGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            41523..42185
                     /locus_tag="PC465_000469"
     CDS             41523..42185
                     /locus_tag="PC465_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2647803.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DN"
     gene            42185..43366
                     /locus_tag="PC465_000470"
     CDS             42185..43366
                     /locus_tag="PC465_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2647804.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTLWSKNFFYFLVISFGI
                     ISTMATVVYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGAKFIIKFY
                     T"
     gene            complement(43547..46207)
                     /locus_tag="PC465_000471"
     CDS             complement(43547..46207)
                     /locus_tag="PC465_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2647805.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWDSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAPKSKGESFKKISETTLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKISASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYDTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(46204..46887)
                     /locus_tag="PC465_000472"
     CDS             complement(46204..46887)
                     /locus_tag="PC465_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2647806.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTYGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            complement(47231..48184)
                     /gene="blaCDD"
                     /locus_tag="PC465_000473"
     CDS             complement(47231..48184)
                     /gene="blaCDD"
                     /locus_tag="PC465_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HDF2647807.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNNKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKCVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            complement(48726..50840)
                     /locus_tag="PC465_000474"
     CDS             complement(48726..50840)
                     /locus_tag="PC465_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2647808.1"
                     /translation="MSENKQVVNCDIIASNSKHNMCEYDAELLTFFPDEIAHLIEINN
                     KLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVK
                     VRDKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
                     YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEK
                     MKSIISTIQKEQNQIIRNDKADTLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNV
                     IILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINFESEKDPLEINDAKW
                     SERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVK
                     KRLEKVAEDIHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISN
                     MFVMVEKKTLEWSDVYPFIYIHATYEGIQEDKIIRHIVIDEMQDYTPIQYAVINLLFK
                     CKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKKIQDISS
                     LEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDAL
                     REEYSVHLISSESSSFTKGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDRSLLYIA
                     CTRAMHKLKLTYTCELTQLIDM"
     gene            complement(51098..51958)
                     /locus_tag="PC465_000475"
     CDS             complement(51098..51958)
                     /locus_tag="PC465_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2647809.1"
                     /translation="MSYKVINVITAIDYIEEHLSEKLDLDIVANAVHYSKYHLHRTFT
                     TSVGLTMHDYIKRRKLTEAAKLLVFSKKPIIEIALIAGYESQQAFTSIFKAMYKKSPN
                     KYRKEQEFYPLQLRFVLKKDNLFSKNVLELEKEIKLASMSDIPLWMNLVRLVIDGFPN
                     LQEEEYIYQLEQYILEERALILKLNNVAIANMVFNRETRSIDFFGIHPQYRNSDIAQV
                     FLKKVIEDFLIDTDISITTFREGDKADTGHRDMIKKLGFAEAELLVEFGYPTQKFILP
                     CVEERDNRQN"
     gene            complement(52569..53193)
                     /locus_tag="PC465_000476"
                     /pseudo
     CDS             complement(52569..53193)
                     /locus_tag="PC465_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860815.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
     gene            complement(53213..53827)
                     /locus_tag="PC465_000477"
     CDS             complement(53213..53827)
                     /locus_tag="PC465_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF2647810.1"
                     /translation="MNEKWLEWAIELQSIAQAGITYGKDIYDIERYERIREISAEMIA
                     YKTDISTEKVRNLFCNESGYQTPKLDTRAVIFENGKILLVKENTGKWSLPGGWVEVNL
                     SVKENTIKEVKEEAGLDITADRIIAIQDRAKHNLPIYAYGVCKIFVLCTVIGGTFKEN
                     IETTEFSYFSENELPELATEKNTEEQIKMCFEACRTDTWTVIFD"
     gene            complement(53895..54257)
                     /locus_tag="PC465_000478"
     CDS             complement(53895..54257)
                     /locus_tag="PC465_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2647811.1"
                     /translation="MKIYDILTRFYIQDIEKAIPFYENLLKEKCSLRFSYKEVGLELA
                     QIGNVLLLSGSDDALKPFIETKSTFMVDSVDEWRSYLLDNGAVVVRDKKKVPTGYNMT
                     LRHPDGTIIEYVQHTKQD"
     gene            complement(54555..55019)
                     /locus_tag="PC465_000479"
     CDS             complement(54555..55019)
                     /locus_tag="PC465_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDF2647812.1"
                     /translation="MTRISNITIAEQSEYCFLAIRKTIDFMVEFSEFSKQSFEKISKY
                     LEERGILSSGAPIVCFHNMDLAKLDVEVGFPVATYIDGKNEILQRIVPAQKIITAIDL
                     GPYELQDPTLEDLFSWANSNGYKLHGDIYYQYLNDINRPASEYLTKMMLPII"
     gene            complement(55283..56704)
                     /gene="nhaC"
                     /locus_tag="PC465_000480"
     CDS             complement(55283..56704)
                     /gene="nhaC"
                     /locus_tag="PC465_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDF2647813.1"
                     /translation="MKERECRKASLFDAMIPITCLILFLSLGVLVYGSSPHVPLIGAA
                     AVAGLVAVYRLGFKWKELELSMFNSIKMAMQAILIIIIIGVLIGTWIVSGVVPCMIYW
                     GLKILSPNIFLVASTLVCAIVSLATGSSWSTMGTVGVALLGIGQSLGMPIGLIVGSII
                     SGAYFGDKLSPLSETTNLAPAMAGTDLFTHIKYMLYSTIPSLLICLVIYGVIGMKYSG
                     QALDIKQIELIRSTLDSTFNTLSPVLLLAPAIVIGLVVFKVPAIPGLIVGAVLGVLFA
                     VVFQGESMNTILDAAQNGYVSSTQIQEVDALLSKGGIMNMMSTVSLTICALSLGGILE
                     KTGMLEVVASSLLRLAKGVFGTVLCTMVTCTITNIIAGEQYLSIVIPGRMYNKEYKKR
                     GIHPKMLSRALEDSGTLTSPLVPWNTCGAYITATLGVSALTYGPYALLNIINPIVSLV
                     LIACKFKIARIEDEPETCLNFDV"
     gene            complement(56734..57798)
                     /locus_tag="PC465_000481"
     CDS             complement(56734..57798)
                     /locus_tag="PC465_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/ornithine racemase family PLP-dependent
                     enzyme"
                     /protein_id="HDF2647814.1"
                     /translation="MYPRLEIDIEKLKHNAKLISQMCHERNIKISFVTKSFCAQKEIV
                     EEICSEGIDHIADSRIQNLKNLQDINLPKILIRIPMLSELEEVINYCDISFNSELGTI
                     KKLNELCESKNIIHKIVLMFDLGDLREGYFYEEDFFNNVREIVRLKNIEIIGIATNLT
                     CYGAIIPSRENIGRLVSIAKRMEEKFGINLEIVSGGNSSSIHLLINNNMPEGITNLRI
                     GESILLGRETAYGENINGTYQDAFKLICQVVECKEKPSVPIGEIGVDAFRNKPVYEDK
                     GILKRAIIAIGKQDINIDSLIPIDTDIKILGASSDHMILDVSNTKYDYKLGDNLEFLL
                     TYGGIMSSSTSKYVSKKIIV"
     gene            complement(57783..59192)
                     /locus_tag="PC465_000482"
     CDS             complement(57783..59192)
                     /locus_tag="PC465_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate mutase L"
                     /protein_id="HDF2647815.1"
                     /translation="MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAP
                     TTVFEGGDVRNGLSGAIKDLANKLSVDDIEYNDMFATSSAAGGLKMTVHGLVYDMTVK
                     AAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
                     ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVF
                     EEHITTAPGMKYIKEMVNENITPTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVT
                     DGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQSELSIDIDAVIENY
                     PPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVG
                     TGGALTRLPSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEAS
                     LKLLLKSLNFEEERLCILG"
     gene            complement(59192..61396)
                     /locus_tag="PC465_000483"
     CDS             complement(59192..61396)
                     /locus_tag="PC465_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892628.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HDF2647816.1"
                     /translation="MLKENKKLDIDYILKDLDKYKPKRRGWVWREHLENLEMGPFKYK
                     DCTKPLKKSVGLPSSKYFNNIDPQPSPVITTEIASGRFEDDIRRMRMAAHHGADHLMV
                     IRTAGQSHFDGLIEGTPQGIGGVPITRKQVRAQRKALDFIEEEVGRPINYHSYVSGVA
                     GPEVAVMFAEEGVNGAHQDPQYNVLYRNINMVRSFVDACEAKKIMAFANIAQIDGAHN
                     ANATAREAWKVMPELMVQHALNSIFSEKIGIDKSNICLSTVPPTAPPAPCLKIDLPYA
                     VALRELFSDYKMRAQMNTKYMESSTREATVTHVLNLLTSVLTRADIQSTITPDEGRNV
                     PWHIYNIEACDTAKQALVGMDGLMDMIELKDVGELRDKARELKERAVLYMEEISEVGG
                     YFESVEQGFFVDSGNYPERNGDGISRKIKGGVGEGTVYEREEDYLAPVTAHFGYNNVA
                     QYDENAIDNPSMLIDGCTFENPDKIIYIDELDDFDNVENRLKESYEYRNGTKIKPEME
                     WCADGIVMITMMLPTDKRTAEFAALEFVKKMNLQEIEVISREVMHESEGTRIEVKGRV
                     PFDIDLNNLVIPEEPKVLTDEEIRADIEEKPMKIVSATVGEDEHSVGLREIIDIKHGG
                     IEKYGIECHYLGTSVPVEKLVDAAIELNADAILASTIISHDDIHYKNMKKLHDYCVEK
                     GIRDKVMIACGGTQVTPEIAVEQGIDAGFGRNSKGIHVATFLVEKRREMSNK"
     gene            complement(61390..61764)
                     /locus_tag="PC465_000484"
     CDS             complement(61390..61764)
                     /locus_tag="PC465_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine aminomutase subunit alpha"
                     /protein_id="HDF2647817.1"
                     /translation="MKKREDDFEVRRKHLQELSEDELKERFWSLATQIVEPMIELGKK
                     NTTPSIERSVLLRMGFSSLEVKPILEGVMERGLIGKGAGHVVYKLAKSKNITVREAGL
                     LLVKGEYWDEVTCLFREGVESC"
     gene            complement(61842..63272)
                     /locus_tag="PC465_000485"
     CDS             complement(61842..63272)
                     /locus_tag="PC465_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent lyase/thiolase"
                     /protein_id="HDF2647818.1"
                     /translation="MNNSTSMKDMSYQAVMGRNNEIMKNAIGLDYSSFEQEGIGFDYE
                     KMMSETGYTLQDIEAIQSQYAVGNTPLIELKNLTKLARKCAKEGKGARIFVKDEAMNA
                     SGSFKARRAATAVYHAKQMGYKGVIAATSGNYGAAVASQAAMQGLKCIIVQECYDSNG
                     VGQPEIIEKARKCEAYGAEVVQLTVGPELFYTFLVLLEETGYFNASLYSPFGIAGVET
                     LGYELAIQFREKYKKDPDIVVCTNAGGGNLTGTARGLIKAGSINTKVVGASVDLKGLH
                     MASDNQFNKKSFTTGHTGFGIPYCTWPDRSDVPRSAARPLRYMDRYVLVKQGEVFYTT
                     ELLAQLEGIERGPAGNTSLAAAFSLAQELDEDKAIVVQETEYTGAGKHICPQLTFARE
                     NGIDIKFGNPREEIAGVNLILPERPELLKCVDIDMNKIRKSFIKNCISNNHIDNIDKL
                     SNRDIEFLMEEVKSSRDFVVDVLNNL"
     gene            complement(63265..63573)
                     /locus_tag="PC465_000486"
     CDS             complement(63265..63573)
                     /locus_tag="PC465_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-ketopentanoate thiolase"
                     /protein_id="HDF2647819.1"
                     /translation="MDAKINDWVIIHNIVLTPEERAPQVPEDTKKVSLEMWVKGFIQS
                     DASIGDLVEVKTITGRLVKGNLLKVNPYYTHDYGKCIPELLQIGIQAKEILFGGVYNE
                     "
     gene            complement(63717..64784)
                     /locus_tag="PC465_000487"
     CDS             complement(63717..64784)
                     /locus_tag="PC465_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-binding protein"
                     /protein_id="HDF2647820.1"
                     /translation="MRKVRVGIWGFGAMGIGMANMILKKEGIEIVSVCSRSTSGKSMY
                     DVLGIERGERPEVIINKNYEEVFREKSVDVVLLATDSFTKKAFDKIIFLLNRKINVIS
                     TAEQMAYPQADDADLAKKMDEVAKENGVSILGTGINPGFVLDLLVLALSGTCEEVTSI
                     KAKRVNDLSPFGKSVMVEQGVGVTREEFIKGVEDKTIAGHVGFVESINMIADGLGWKL
                     DKIEQTKEPIMTTVDRKSKYGEALAGNVAGCRQCGYGYVNGEVLIEMEHPQQIIPEAE
                     GIKTGDYVSIKGIPNIDLQINPEIPGGVGTYAMIVNSIPLIINARPGLKTMLDIPVPR
                     AIMGDIRNQIEVELEEESKAN"
     gene            complement(65040..66413)
                     /locus_tag="PC465_000488"
     CDS             complement(65040..66413)
                     /locus_tag="PC465_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2647821.1"
                     /translation="MNEILENIDEGVHFVNKDGKTIIYNNSVQKMEKMNRHDILTNSF
                     FDIVNKMKINRSTLLEVLEKREVIKDNIQKYLDKNGKEITAINTTIPIDIKGEFVGAL
                     EISKNMTTIENLLNRNYKKNLVNKVSSRQKKGYEFDDILGESNLIKEAIAKSKKACKS
                     DASVFIYGETGTGKELFSQSIHYGSNRKNYPFIAQNCAALPESLFEGILFGTSKGGFT
                     GAIDRPGLFEQANKGTLLLDEINSMPIMLQAKLLRVLQEGYVRRVGGTKDIPIDVRII
                     ATTNESPKVILNEHKMRKDLYYRLNIIHIKIPPLRDRKEDIPLLCKKFISKYNKKLNK
                     KVVGISDEAIKILKNYDWQGNIRELENIIYCTMSMMEDEVQIETSMINLNDYYNLKEN
                     KESNNYSLNDLEDKTLSKIISEIEEKYIYESLEKASYNITKAASILGMNRQNLQYKIK
                     KYNIKIL"
     gene            complement(66956..68914)
                     /locus_tag="PC465_000489"
     CDS             complement(66956..68914)
                     /locus_tag="PC465_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2075 domain-containing protein"
                     /protein_id="HDF2647822.1"
                     /translation="MKRAYYSSSVNEFIVKDIFTIFGEITCNDQFAADDLQKNTWKKE
                     IGILKRELSTFKDGHLLFEYTIPRIGSRIDNVLIYKGIVFLLEFKVDEDTYPRHAIEQ
                     VTDYALDLNCFHKESHDKLLVPILICTKAPQKDQRIRMMKENILETYCCNEFNIGKYI
                     KKICTTYNRSSFNSDTWINSLYMPTPTIIEAAQALYMGHNVEDISRNDASAKNLNQTT
                     KAINKIIDYSKTHNRKSICFITGVPGAGKTLAGLNIAIERQKVDENEHAVFLSGNGPL
                     VDVLQEALARDDVTRNGIRKSEAIRKAKEFIQIIHHFRDEAISVDTPPIERVTIFDEA
                     QRAWDEPNLTNFMKRKKGVLDFNMSEPEFLISILNRHIGWATIVCLIGGGQEINKGES
                     DGISGWFESLRNNYSDWDVYISNKIIDEEYSKGNSFDELTEGVNYRIIDDLHLSVSLR
                     SFRSENVSTFVKAVLDVDKVAAKELYNQFKKDYPICVTRDLELAKKWVRDKSKGSQRY
                     GMTASSGAKRLRKYGVWVQNKIDATNWFLNGKDDVRASYFLEETATEFDIQGLELDWT
                     IVCWDGNLRFKNNHFEYYNFNGTKWQNINKEDNILYLKNAYRVLLTRARQGFIIFVPI
                     GDESDITMQPNFYNGVYEYLKEIGIEEL"
     gene            complement(69107..70297)
                     /locus_tag="PC465_000490"
     CDS             complement(69107..70297)
                     /locus_tag="PC465_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HDF2647823.1"
                     /translation="MDKNKYKIETLMNHVGENLDGDYGAVNPPIYQSSIFARSTYEDI
                     EAYFEGSKDGYLYSRTKNPTNDILEAKLSALANAEASITFGSGMGAISSAILHFVKNG
                     DHIIASNNLYNPTMNFITKELKEKGNIENTIVEGDRIEDFENAIKQNTTLIYLECPST
                     SVFKMQDIKAIVALAKTHNIKTVIDNTWATPLYQRCIEMGIDLEVHSLSKYLNGHSDV
                     VGGCIIGSKKDIEEIRGSELALYGAKLAPFEAFLVIRGLRTLHARLSVHTKNAKEVVE
                     FLDNHSAVTKVYHPLSKYFNQKELAKKQLLNYTALLSFEIDAKDVNDVKKFVNKLDLF
                     KIGVSWGGHESLVFAPNIAILNEMTLEQAKALNVSPYTIRISLGLENSEDLINDLNDA
                     LSIL"
     gene            complement(70397..71863)
                     /locus_tag="PC465_000491"
     CDS             complement(70397..71863)
                     /locus_tag="PC465_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HDF2647824.1"
                     /translation="MKRKVTIQKQAISIVLFMAVLFCGLLLPMINNKPEYSLPIESIM
                     FISASIISLFIVVTTNKTWEEVFESGLDGVKGALPGLIILLVIGPLIAGFIMSGLMPM
                     LVYYGVKLINPRFVYATALILSALFSSFTGTSWGSAATIGVVMMGVGNAIGANNAIIA
                     GAIVGGAYFGDKMSPLSDTTNIAAIASKVNLYDHVASMLWTTGPATIIALVIYIACGF
                     IFPATNTNLNSPEITRLLADLSGMFNFNIILFIPLLIVLVGSAMKKPAIPVMTIAAFL
                     SLAFAVIFQGFSLADVLIGLNSGFSLDMVTWHEYAKPIEGQAYILGFFQKGGFWELGK
                     LLPISTSILFVVGVLGSIDAMPATVNVIFGWVKSRTAIICSSLLTGIAMIAMTANGIA
                     CSFVTAGIFGDKYDENNIDRRVLSRTTEDTGTLLEVLFPWTPAAIFFTQTLGVNVGEY
                     ALWSIVNWGTPIIAVILAVTGIGTYKNSKDKKQSNKVS"
     gene            complement(72140..72955)
                     /gene="rhaD"
                     /locus_tag="PC465_000492"
     CDS             complement(72140..72955)
                     /gene="rhaD"
                     /locus_tag="PC465_000492"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HDF2647825.1"
                     /translation="MSIMEMNFIKDFMKITYDAWLKGWHERNGGNITYRLTPEEISGI
                     KEFITEEIEYIPIGVTVENLANEYFLVTGSGKFMRNISINTVQNVGIVKIDEKGENYA
                     IVWGLDKAKPTSEFPSHLMSHSIKKDKTNGLHRVIMHSHTTNLIALTFILPLEGKVFT
                     RELWEMATECPAVFPEGIGIVPWMVPGGIEIAKATQNLMEKHNIVIWAHHGTFCSGET
                     LDLTFGLMDTVEKSAEILVKVISMGGKKQTITGDNFRDLSKNFKVSISEDYLY"
     gene            complement(72966..74222)
                     /gene="rhaA"
                     /locus_tag="PC465_000493"
     CDS             complement(72966..74222)
                     /gene="rhaA"
                     /locus_tag="PC465_000493"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HDF2647826.1"
                     /translation="MELKQRYEVAKKEYEKWGINVEEVLRVLSKVKISIHCWQGDDVT
                     GFEGNQQRLSGGIASTGNYPGKARNPQELRRDLDKALSLIPGKHKVNLHAIYAETGGS
                     FVDRDELKPEYFENWVKWAKERGLGLDFNPTIFSHPKSSDGLTLSHPDKKIRDFWIKH
                     CIASRKIGEYFGKELGQTCLTNIWIPDGYKDIPSDRLGPRRRLKESLEEILKVEINRE
                     YNLDCVESKVFGLGVESYTVGSNEFYLNFASKNNIISLLDTGHYHPTELVSDKLSSML
                     LFSDKVALHVSRPVRWDSDHVVILDDELKEIAKEIVRNDALDKVIIGLDFFDASINRI
                     AAWVIGTRNMIKALLSAMLMPHEELRKLQDEGDFTKRLAIMEEFKTYPMGDIWNYYCK
                     INNVAVKEDWIEVVKEYELTELLNRK"
     gene            complement(74243..75637)
                     /gene="rhaB"
                     /locus_tag="PC465_000494"
     CDS             complement(74243..75637)
                     /gene="rhaB"
                     /locus_tag="PC465_000494"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HDF2647827.1"
                     /translation="MRYYLAIDIGASSGRHIISYINNGKLEIEEVYRFKNNLIKKDGH
                     FCWDISKLFSEIKNGIKKCIKINKIPVSVAIDTWAVDFVLLDEKDNILGNCVSYRDNR
                     TDGIMEEAFKIIDKKELYLKTGIQFQKFNTIYQLLAIKNQQPDLLEKAKSFLMIPDYF
                     NFLLTGKKVTEYTNATTTQLVNTTTNNWDEEIINKLGFDKMLFAKIKTPKTILGSLKK
                     ELVEELGCDLEVILPVTHDTGSAFMSTPVKNRSILLSSGTWSLLGVELERPKCKLEAL
                     DYNFTNEGGYEYRYRFLKNIMGLWMIQEARKCYDSKHSFTELVEHARLSEGFKSIVDV
                     NDDRFLNPENMVQEIIKYCIETNQTEPQTVGEVAYCIFNSLAKSYSKSINEIEKIIEE
                     KLETISVFGGGCQNELLNELIAKESGKKVLAGPVEATALGNIVCQLIAKNELNDLEQA
                     RDIIRNSFDIIQYN"
     gene            complement(75844..76815)
                     /locus_tag="PC465_000495"
     CDS             complement(75844..76815)
                     /locus_tag="PC465_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2647828.1"
                     /translation="MRQYIHDKLREITEEEKNILEGNYIIDKSIYTDNSQFIIDSNKL
                     LNIDELIHIRKHTRFAQFPKHKHNYIEFNYVYRGKLVQTIDEYKINLKQGELIFLNQH
                     VIHEIEASDEEDIIINFIIKPEFFDYIISLLENDNKIMNFLMTTLYTNYNLGEYIYFK
                     VSEKEEIQDIIEKIIIELYEPSVVNKVKIKLLVGLLLVELVKNSEDVENHAVDNYEKM
                     MIIEILKYIDKDYKKGSLSEIASNLNQGDYKISKLVKKHLGYTFKDLVQEKRLSKACE
                     LLVSTNLSIAEIIENVGYENLTYFYKIFKNKYGITPKEYKKNIKNSQ"
     gene            complement(76939..77220)
                     /locus_tag="PC465_000496"
     CDS             complement(76939..77220)
                     /locus_tag="PC465_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647829.1"
                     /translation="MKDETLEDILKQKTQAERYILEYIVTKNVKKLDNKKIVSILHTI
                     LCWEEINGTIVLTDKNILSLDEDIIISKHRRFIDIPKHKHNFIEFHLMS"
     gene            77406..77726
                     /gene="rhaM"
                     /locus_tag="PC465_000497"
     CDS             77406..77726
                     /gene="rhaM"
                     /locus_tag="PC465_000497"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HDF2647830.1"
                     /translation="MNTIRKCFKMKLFKGFENEYKKRHDELWSEMIDMIHEYGGSNYS
                     IFLDEETNYLYGYIELKDAKLWDKSSETAICKKWWNYMSDIMETNEDNSPVSIELKSM
                     FYLK"
     gene            complement(78390..78530)
                     /locus_tag="PC465_000498"
     CDS             complement(78390..78530)
                     /locus_tag="PC465_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647831.1"
                     /translation="MENLMMSIITGVIASYIYDKLKSHSERPTKSGWELNIKFQKSKS
                     SK"
     gene            complement(79063..79950)
                     /locus_tag="PC465_000499"
     CDS             complement(79063..79950)
                     /locus_tag="PC465_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF2647832.1"
                     /translation="MKLSKTLLAIGMSVSLLIASCPTSNALSSINSIKGTNKYETAGL
                     IADKQNYDIAILINSENGLSDGLSASGLSGAKNAPILLTKKDTIPSETLKRLEKVKEV
                     YLIGGKNSIGASVQKILSDKKISINRISGTDRIDTSHKVAKEIGRVSTVKKVILTNAF
                     KGEPDAMSVASIAVRDKSPIVLTDGNTTSFATDGLETYAIGGKVSMSDKLINETKATR
                     IGGVDRYDTNKQIINKFYNGSKEFYIASGTDLVYSLVGSTIAQKTPIVLVGNGSNKSI
                     LKNASKITAIGNIDDVVIK"
     gene            complement(80121..80324)
                     /locus_tag="PC465_000500"
     CDS             complement(80121..80324)
                     /locus_tag="PC465_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4236 domain-containing protein"
                     /protein_id="HDF2647833.1"
                     /translation="MGFNFRKSINLGGGLKLNLGKKSVGISAGVKGARVSVNSKGRKS
                     ATLSIPGTGISYTKTSTKKRKPK"
     gene            complement(80411..81445)
                     /locus_tag="PC465_000501"
     CDS             complement(80411..81445)
                     /locus_tag="PC465_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHYH domain-containing protein"
                     /protein_id="HDF2647834.1"
                     /translation="MFKKKLIAVAMSITMISVGSFSYAHSGRTDSSGGHRDNKNKSGL
                     GSYHYHCGGYPAHLHNNGGCPYTGGGSSSGTTTSVNNEEKQKRSVGEKGYNQGYEDGY
                     KGNYSSSNYSGDYSDTYESKYSEGYEKGKAKLEEEEKVAKETGYNLGLTGAKSNNTYE
                     KEVLKNAYDTGYSTGYNEYKTKKIEEYKAKGIEDSNKDKEKMTFEENIDSEFIDAYNN
                     AYDEIQEQLKNDYTTQGFESAIKGERFDTSTIGNVKYANWFKEGYDNGKVKLPKAKES
                     VYNQGYNEEDFSIPDEMKSIETKLKGVYDEGLEKREEEKSRNATYGVGAGIAAVVAGV
                     VYKKKKRKKI"
     gene            complement(81984..83738)
                     /locus_tag="PC465_000502"
     CDS             complement(81984..83738)
                     /locus_tag="PC465_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007790003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2647835.1"
                     /translation="MNTKVKLIKASNTGARNRNALRLDLKRVAAYCRVSTDSKDQLES
                     YKSQVDYYTNLIKNNKNWTLAGIYADEATTGTTATKRADFMRLISDCQNGDIDMIITK
                     SISRFARNTLDTLKYVRLLKENNVGVVFEEENIDTLTMDGELLLTILSSVAQQEVENT
                     SAHVKKGLKMKMEKGELIGFQGCLGYDYDPITKSISINEEEAKIVRYIFKRYLEGNGG
                     SVIGRELEEQGYLTPRGKTKWSDTTVLGVIKNEKYIGDILMGKTFTVDPITKRRLANF
                     GESDKYHIENHHEPIISKEDFEKAQEIRLRRAQNRNTIANKDRKREKLSRQYAFSSML
                     ECGFCGEILSRRTWHTSSIYKKINWQCVKSTKKGKKYCPHSKGIQEAAIEKAFVESYR
                     QLCHADSTVIDDFLKIVEEEINDNTLVKDLKKLENQLNRIISQERKLVDLHLEDSIDE
                     EVYAKKYKKLTKQKEELLDEKKTLELTIKDEDSIKERLKQFKKVLENKEIIEEFNRTV
                     FESIVDKVVVGRIDKDGTVHPYDLTFYFKTGVKDSQDSNNFKDKRKNAKDNDINKLCS
                     YKNDEDKKLCSQSKDNAL"
     gene            complement(83794..83931)
                     /locus_tag="PC465_000503"
     CDS             complement(83794..83931)
                     /locus_tag="PC465_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012797125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647836.1"
                     /translation="MKAIKIYSMRVAMLCRLYDLKLINDKEYAKIKNRIENDYKKRDR
                     K"
     gene            complement(84469..84879)
                     /locus_tag="PC465_000504"
     CDS             complement(84469..84879)
                     /locus_tag="PC465_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2647837.1"
                     /translation="MDKEYYLFVEGKKVVVSKEVYLAYHSELNKEKYQMRRDRLNNCF
                     FFCSYDHDGNFEENLEDLEFDVEKIIETKEMIEEVRRAIYKLNPVERDLIESLFYKEE
                     TIREVAAKLNISHPAVIKRRNKVLEKLKEMLEDF"
     gene            complement(85149..85664)
                     /locus_tag="PC465_000505"
     CDS             complement(85149..85664)
                     /locus_tag="PC465_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647838.1"
                     /translation="MYADSDLKFEEISSAAKLILSLYRQVTWAVDSRANFMMFESKEN
                     YGSTSESAYLYLSTFAPERVEEKFNNRVSNVMDSKLILLIIYDACVRLKVYPEYGEIY
                     HKIIYNYYISEKKITDEACMRSVSLERTVYYQRKKEAIALVGVIIWGYTLPTAISQLK
                     DGRSIEEIMNI"
     gene            85859..86260
                     /locus_tag="PC465_000506"
     CDS             85859..86260
                     /locus_tag="PC465_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2647839.1"
                     /translation="MAFADRLKDFREKEKLSQADFAKMIGISTRTLVHYEDGERYPRD
                     VEVYKKIAEVMDCDYNYLLEESDEFLNRVYNMGGKRELEKARALTEGLSSLFAGGEIS
                     DEDKDAAFEAITRAYWEAKRENKKYGRKKKD"
     gene            86269..86817
                     /locus_tag="PC465_000507"
     CDS             86269..86817
                     /locus_tag="PC465_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004818771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HDF2647840.1"
                     /translation="MSMNRYIYDKVNRLIKKYKTRDPIELIEALNINLVYLPETKILL
                     GMYHYIQRNRFIFISSNTNFNRKTILAHELGHDQLHRDYCMSGGAFHDQTVLNPTNKF
                     ETEANIFAAHLLISDEDILDNINDQVCDYEIAGQLGVDINLLNLKISELAKMGKFNKP
                     VNVNIPQGDFLKNYRPEHDDYY"
     gene            86826..87308
                     /locus_tag="PC465_000508"
     CDS             86826..87308
                     /locus_tag="PC465_000508"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647841.1"
                     /translation="MGIFIAGYFLLILSGIVFYYLITTYSVKISAFLIDFIVVGLGFY
                     ISIKDKLDSKLAIPLSITVVIIYGILLVLINRKLPKVSRFLNYIIAFIGSSVALWLAL
                     DFITNTLAAFKIIGQTYHQLPITKSMMINSFIHYVIVFLISIPVFKGRMKFILGGNYE
                     "
     gene            87301..88374
                     /locus_tag="PC465_000509"
     CDS             87301..88374
                     /locus_tag="PC465_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence RhuM family protein"
                     /protein_id="HDF2647842.1"
                     /translation="MSREMDKNKDENQKKKELQIRSSAAEYLTFVAANGDDQEAIEIR
                     YEDENIWLTQKMMAALYDVSVSAINQHLKKIFDDNELDENSVIKKYLITANDGKSYNT
                     KHYNLQAIIAVGFKVNNERAVQFRKWANQIVKDFTIKGWAMDDERLKNSGTKLTKDYF
                     EKLLVKIREIRLSERRFYQKITDIYATSLDYDPSAKATKRFFAAIQNKLHYAIHGKTA
                     AELIVDRANHKTKNMGLTTWEGSPDSKIHKYDVVVAKNYLNEEELNQMQRIVSSYLDM
                     AELQAERHIPMTMEDWEKRLNGFLQLWDKEILNDAGKVSAALAKKHAESEFEKYRIIQ
                     DRLYKSDFDKFLELENDTKKLEE"
     gene            88545..88901
                     /gene="mobC"
                     /locus_tag="PC465_000510"
     CDS             88545..88901
                     /gene="mobC"
                     /locus_tag="PC465_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004026808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HDF2647843.1"
                     /translation="MDNRKRNNQLKIYLTDEEKEIFEKKMKLANCKTMSHFLRKCVLE
                     KEIYVVDLEPFRNLQWLLSNATNNINQIAKATNTTGVIYKNEIESMNKQIEKLSKEIW
                     QIHSLLLNKSKESSGD"
     gene            88903..90234
                     /locus_tag="PC465_000511"
     CDS             88903..90234
                     /locus_tag="PC465_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDF2647844.1"
                     /translation="MAITKIHPIKSTLNLAIDYITKSEKTDEKILVSSFKCHPSTAHI
                     QFMKTREDNDTKGTVLARHLIQSFLPGEVDPIKAHEIGMELCKKILKENYEFVLATHI
                     DRGHIHNHIIFNNVNYKTGKCYQSNKKSYHKIRYQSDELCKANKLSVIDKYYEAYKRK
                     YKTAGKSWYEYDQNKKGNSWKSKLQFDIDRVINKSNSWEEFLENMKSLDYEIKFGKHI
                     AFRHKDKKRFTRAKTIGEDYTEEKIKERIDLAIINKANPIKKRVGNVIDISTNEKAQS
                     SKGYEVWARKHNIKTMADSIIKLREQGINSITQLDDLIKKSADDRQDLLDKIKKFETE
                     MKSLSKDMENIYTINKYREIYKYHKKNPEDKQFEEEYYSELSVYKIAAKEILENYNKL
                     PNTKEILSKLDKLQEKKNTLMQEYSLNKEQFSDLVQYRKNYENYYGKEVER"
     gene            complement(91120..91812)
                     /locus_tag="PC465_000512"
     CDS             complement(91120..91812)
                     /locus_tag="PC465_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019108018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2647845.1"
                     /translation="MELKKITSRVFYYPHQPETDRPMLAYLNGDKIALAIDAGNSADH
                     VDEFYKSLEIENLKKPDFTVITHWHWDHTFGMHKIHGLSIAHHKTNEFLKQERAKLSD
                     SAYIKFLINDDECLAREYVDNKRIIAVLSDIQFEKELTLNLGGITAMIFHTVSPHSED
                     TVLIYIPEEKILFLGDSTSEDFYNDGYMDKEKLMSLTNLIESFDCKYCILSHAEPLTK
                     SDLLDYLKSILK"
     gene            complement(91803..92192)
                     /locus_tag="PC465_000513"
     CDS             complement(91803..92192)
                     /locus_tag="PC465_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019117958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDF2647846.1"
                     /translation="MNKQELYQIAFSIINHKKLRNFGTSGHVACALETNSGNIFTGIC
                     IDLPCSIGLCAEQSAIAEMVKNNETAIKRIIAVFEDGSILPPCGRCREFIAQIDNQNI
                     ETQIVLPEMEEVLLKDLLPERWDGKWN"
     gene            complement(92238..92762)
                     /locus_tag="PC465_000514"
     CDS             complement(92238..92762)
                     /locus_tag="PC465_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HDF2647847.1"
                     /translation="MQLIREDFSLPFLKQLKQVLRKECASLPMDLKCLLGAHIKPLEQ
                     SIDRVEGLSEILRRSNPKMALCHTDIHNWNLMQRDEQLVLIDWEGLKLAPVKADLMFF
                     VDKPYYDVFMNIYLKLHKDFLINTDALLFYHIRRKLEDIWEFIEQLLYDNQEDKERNE
                     TIKVLDGELNNLVF"
     gene            complement(92979..93710)
                     /gene="erm(A)"
                     /locus_tag="PC465_000515"
     CDS             complement(92979..93710)
                     /gene="erm(A)"
                     /locus_tag="PC465_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000810833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(A)"
                     /protein_id="HDF2647848.1"
                     /translation="MKQKNPKNTQNFITSKKHVKEILKYTNINKQDKIIEIGSGKGHF
                     TKELVEMSQRVNAIEIDEGLCHATKKAVEPFQNIKVIHEDILKFSFPKNTDYKIFGNI
                     PYNISTDIVKKIAFDSQAKYSYLIVERGFAKRLQNTQRALGLLLMVEMDIKILKKVPR
                     AYFHPKPNVDSVLIVLERHKPFILKKDYKKYRFFVYKWVNREYHVLFTKNQLRQVLKH
                     ANVTDLDKLSNEQFLSVFNSYKLFQ"
     gene            complement(93768..93899)
                     /locus_tag="PC465_000516"
     CDS             complement(93768..93899)
                     /locus_tag="PC465_000516"
                     /inference="COORDINATES: protein motif:HMM:NF033690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="erythromycin resistance leader peptide"
                     /protein_id="HDF2647849.1"
                     /translation="MYMYCSSRYYFISFIMKKIKGGKGMGMFSIFVIERFNYQSNQK"
     gene            complement(94444..96093)
                     /locus_tag="PC465_000517"
     CDS             complement(94444..96093)
                     /locus_tag="PC465_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000644977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HDF2647850.1"
                     /translation="MKAKPWEGGKIIMKEKFARWNILFLQYLKRDWKKIIIWVLGLGM
                     FSAGFVPAFKEIAKGQGLVGMFETLQNPAMISMVGPTPVETGADYTLGAMYAHEMLLF
                     CGLFAMIMSILHVIGHTRKEEDLGLTELLRSFQIGRQANSLAAIAEIVFINGILALFI
                     AVVMISFGADTISIFGSVLYGASIGMAGIIGAGIALIMAQIMPTSSAATGSSLGIVGL
                     LYIVRAGTDVSNVDLSMMNPLGWTYLTFPFTDNNWFPLIFALIFSIIVVFIAFSLEGG
                     RDMGAGYLPQREGRESAKQSLLSVRGLFININKGVIISWLIAYVVMGAAYGSIYGDMQ
                     TFLESNEMMKQMFSHTGFSIEESFTGTVMMVLIGLVSILPIAIVNKLFSEERRLHLSQ
                     IYATKVTRSQLYWTSIGLSILSGLLGVLLAAGSLGGTAISAMGNSGEMDIVDFFAAGF
                     NLFPTVLFFIGLAALALGWAPKLGKIVYIYLTFSFLLNYFSGLIDLPEWFLNTAIQSW
                     MPQMPMDDFEASVFLTVTIISIALIVIGFLGYSRRDMNEGA"
     gene            complement(96083..96964)
                     /locus_tag="PC465_000518"
     CDS             complement(96083..96964)
                     /locus_tag="PC465_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000129978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2647851.1"
                     /translation="MTDIVKVQGLQKKFGKFQALRDVSFTIKSGEVVGFIGPNGAGKS
                     TTIRALLGIIKRDAGIAEIFGKDVWKDSLEIHKRISYVPGDVALWGSLTGGEIIDLFI
                     KLHGSGDKEKRDYLIKRFELDPKKKAKGYSKGNRQKVGLIAALSVDSDLYIFDEPTSG
                     LDPLMEQVFQEEVEKIKASGKAILLSSHILSEVERLADKVVIIRQGEIVETGTLDELR
                     HLTRSTVTLVTSGDVSKMAFVDGVHDFVQNDSQATFSVDNQYLNSILIEASKLGVTRF
                     ESIPPTLEDLFMRHYES"
     gene            complement(97049..97675)
                     /locus_tag="PC465_000519"
     CDS             complement(97049..97675)
                     /locus_tag="PC465_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006309255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2647852.1"
                     /translation="MIIYSKFNNLKPEKQKQIINAAIKEFVRNGFEKASTNEIVKRAN
                     ISKGSLFNYFNSKKDLYLYLIEYSSKAIVNLNEEIDLSETDLFKRIERVALQKFYVQQ
                     KYPQAFEFLASTKQEESVEVKDIIKQRLNPIYNQAINKLYKDIDYSKFREGVDIEKAI
                     EILNWTMFGVGEKGLKELFTFDDIGRFGEKYLEEWNVYAELLKYSFYK"
     gene            complement(98233..98889)
                     /locus_tag="PC465_000520"
     CDS             complement(98233..98889)
                     /locus_tag="PC465_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF2647853.1"
                     /translation="MEYKDIRENLEEMMNDNYKDFIKAIVSIEKGINDEKALEEVYVL
                     YMNNDTTGLLSDDFDYMIDDMKEQGKIVENVSDIEEKDDLINLVGNIAGKVENLEREN
                     ANGEKFKVSNFSIVSKDDDGNKIYTNCSAYGDKTKDIENLKQGDFVKIFGQVKTSIDN
                     NGKEHKNVRILSSKLLKAKEQVKSQDKDKKSILGQIKSFKTDDKAKSNKKDHSKGTER
                     "
     gene            complement(98933..100261)
                     /locus_tag="PC465_000521"
     CDS             complement(98933..100261)
                     /locus_tag="PC465_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HDF2647854.1"
                     /translation="MTSKTPVRVAEDVDEASLSYSEIKALATGNPLIKEKMDLDNEVT
                     KLKMLEANYKSNKYKLEDKVNKIYPQSILKTEMEIQAVKEDIASVEKLGEGDSKFTSI
                     SLGANKILDKKEAGEKLLEEIKKVKINDSKVIGKYRNLDLQVSYNFMTNNHTFKLLGK
                     AEYFGEFSNSTDGNITRLDNAIEKMPSRLERLNQNLENYEESLENAKVELTKPFEKAD
                     ELRDKTLRLAEINKLLDMGEVEELENQSPLLEDLKRAIVDYTNYEFSESNSYEDFDKL
                     YPDLSHIGLAYTETPDGKHSIQYEVNLEEKTWSQYVDDVAIRTESFVEEDMSNSQAIK
                     DMTEAIKMSSFDDLVSVDEEDLKQALGLEIDDDGNFYDPLAKDLDNDGIPDRYDNDFK
                     DSDYFESTYDVEDNLHAREEKPSILGQISKFKSEGEKDKNQEKNEKGQER"
     gene            complement(100395..102065)
                     /gene="ltrA"
                     /locus_tag="PC465_000522"
     CDS             complement(100395..102065)
                     /gene="ltrA"
                     /locus_tag="PC465_000522"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019034340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HDF2647855.1"
                     /translation="MNSKMCATTNRAKNWESIDFSLAESYVKKLQMRIVKAWKMSKYG
                     KVKSLQHLLTTSFYAKALAIKRVTENQGKKTSGVDGELWLTPQAKYKAIEKLNLRGYK
                     PKPLKRVYIPKKNGKKRPLSIPTMTDRAMQTLYKFALEPIAETTADPNSYGFRAKRCT
                     QDAIEQCFTSLNKKKSAKWVLEGDIKGCFDNISHEWIMNNIPMNKSLLKLWLECGYIE
                     KQRLFPTETGSPQGSPISPVISNMVLDGLEKAIKEKYHKRTVNKKAYFPKVNFVRYAD
                     DFIVTGESAELLENGVKPIIVKFLEERGLELSEEKTLITHINDGFDFLGVNIRMYKDK
                     LLTKPSEKNFKAIVDKIRQIIKDNPSMKQEILIRKLNPIIIGWINYQKYNVSSKAFEK
                     LDYEIYKCLWNWCVRRHPKKSRKWIAKKYFHTIGNRTWTFSVATGDRMENGEKYYLRL
                     KYATDTDIKRFTKIQAEANPFDENWQIYFEEREELKIRNELKGRTVINRLYKTQNGIC
                     PVCGEKITLDTDFRVHQTTQNNITLKTLVHPWCHRKLHINDKENTLAL"
     gene            complement(102642..103430)
                     /locus_tag="PC465_000523"
                     /pseudo
     CDS             complement(102642..103430)
                     /locus_tag="PC465_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989360.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
     gene            complement(103432..103620)
                     /locus_tag="PC465_000524"
     CDS             complement(103432..103620)
                     /locus_tag="PC465_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004611678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2647856.1"
                     /translation="MKEQKHSYSQCIGKTTFIVNVKQSESAKKPLNTVFQDICKHEVL
                     GDFFTDKSFNLENPQKVS"
     gene            complement(103740..105005)
                     /locus_tag="PC465_000525"
     CDS             complement(103740..105005)
                     /locus_tag="PC465_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004611677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HDF2647857.1"
                     /translation="MAKNNKADMSCARVKKYTASDVSKAERHNERKNETYENMNVIEE
                     RIPYNVHFKKPFAPTYMEQLKQMETDGMVSLRGLRKDATLFNEIVIDVNTMYFERNGG
                     YEYAKQFYEEAFHFIEEKFGADNVISAVMHADEINVAATEELGKEVYHYHLHAMVLPV
                     VEKEILWSKRCKDEKLRGTVKEVVHQISHSKKWKSDIPLTDEKGNPLLRKNGKPMFRA
                     SYSILQDELFNHMTEQGFKGFQRGEYGSTAEHLTSLQYQIKQDKERLEKLQKRIQREQ
                     IKYEPARNVSKTYNEIDRMGQKTITGKMAISKEDYSELTALAKEGITSRAEISELEQS
                     ANYYRQKYFDSANALERMKTKYDELKEKCRPFLQALEHFPEVAKLFTEKVKQLFSFKE
                     AQERAEKEAREKERQERIKARRNKRGMER"
     gene            complement(105186..106208)
                     /locus_tag="PC465_000526"
     CDS             complement(105186..106208)
                     /locus_tag="PC465_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2647858.1"
                     /translation="MKLNENEMNFSVPLEIIKASEIEPKEVKWLWYPYIPFGKVTLLQ
                     GDPGDGKSKLMLSIAALLSKGEPIPFTETEENEPMTIIYQTTEDDADDTVVPRFNSAG
                     GDGENLIFIKEDEKTLSFGDNRIREAIEKYNAKLLILDPLSSYIGENCSMNNANETRA
                     EFNHLIAVAKDTGCAIVIIAHMNKMKDNNPLYRTNGSIDIAGAARSILAITRTPNKEA
                     PAERYLVQVKSNLAPTGSAILFEVAEKGVNFISEMEMTAEEAFLSLAPQIGRPNEKEM
                     KAKSFLIEMLQGGEMLSSDCEEKLEAAGFKKSTIKKAKKNAGVISKKKGFLWYWSLPM
                     SDIPRE"
     gene            complement(106457..107080)
                     /locus_tag="PC465_000527"
     CDS             complement(106457..107080)
                     /locus_tag="PC465_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-11 chloramphenicol O-acetyltransferase
                     CatP"
                     /protein_id="HDF2647859.1"
                     /translation="MVFEKIDKNSWNRKEYFDHYFASVPCTYSMTVKVDITQIKEKGM
                     KLYPAMLYYIAMIVNRHSEFRTAINQDGELGIYDEMIPSYTIFHNDTETFSSLWTECK
                     SDFKSFLADYESDTQRYGNNHRMEGKPNAPENIFNVSMIPWSTFDGFNLNLQKGYDYL
                     IPIFTMGKYYKEDNKIILPLAIQVHHAVCDGFHICRFVNELQELINS"
     gene            complement(107262..107633)
                     /locus_tag="PC465_000528"
     CDS             complement(107262..107633)
                     /locus_tag="PC465_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HDF2647860.1"
                     /translation="MQRFITDERTGIRYELIGDYYYPCLTAEEKPLLSRYGRMRERYL
                     KEHKRVLYYTLMTSGKLYEHLAEIDTSACDMAEYLIKEMARKQGVTEQLKAVDMMRWI
                     GLMNNIRACVDEIVLNDIVYS"
     gene            complement(107558..109681)
                     /locus_tag="PC465_000529"
     CDS             complement(107558..109681)
                     /locus_tag="PC465_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004611674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2647861.1"
                     /translation="MSRTSRITALYERLSRDDDLTGESNSITNQKKYLEDYARRNGFE
                     NIRHFTDDGFSGVNFNRPGFQSLIKEVEAGNVETLIVKDMSRLGRNYLQVGFYTEVLF
                     PQKNVRFLAINNSIDSNNASDNDFAPFLNIMNEWYAKDTSNKIKAIFDARMKDGKRCS
                     GSIPYGYNRLPSDKQTLVVDPVASEVVKRIFTLANDGKSTRAIAEILTEEKVLTPAAY
                     AKEYHPEQYNGNKFTNPYLWAMSTIRNILGRQEYLGHTVLRKSVSTNFKLHKRKSTDE
                     EEQYVFPNTHEPIISQELWDSVQKRRSRVNRASAWGTHSNRLSGYLYCADCGRRMTLQ
                     THYSKKDGSVQYSYRCGGYASRVNSCTSHSISTDNVEALILSSVKRFSRFVLNDEQAF
                     ALELQSLWNEKQEEKPKHNQSELQRCQKRYDELSTLVRGLYENLMSGLLPERQYKQLM
                     KQYDDEQAELETKMETMKTELAEEKVSSVDIKHFISLIRKCKNPTEISDTMFNELVDK
                     IVVYEAEGVGKARTQKVDIYFNYVGQVDIAYTEEELAEIETQKEQEEQQRLARQRKRE
                     KAYREKRKAQKIAENGGEIVKTKVCPHCNKEFIPTSNRQVFCSKECCYQARQDKKKTD
                     REAERGNHYYRQRVCAVCGNSYWPTHSQQKFCSEECQRVNHNKKTLEFYHHKKEKEKL
                     QCKDLSQTKERVSDMNLSGTITTPA"
     gene            complement(109753..110763)
                     /locus_tag="PC465_000530"
                     /pseudo
     CDS             complement(109753..110763)
                     /locus_tag="PC465_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989360.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            complement(115259..116209)
                     /gene="dcm"
                     /locus_tag="PC465_000531"
     CDS             complement(115259..116209)
                     /gene="dcm"
                     /locus_tag="PC465_000531"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002836657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HDF2647862.1"
                     /translation="MNKVKILELFGGIGAIRKAFINLKIPYEVVDYVEIDKACVKSYN
                     ALYGEDYKAKSVVGYKAPNEKIDLVMHGSPCQDFSRIGKKQGGAKNSGTRSSLLFETI
                     RIIKEMKDKPKWIIWENVKGVLDRNMRDSFFIYLKELESLGYESKYKILNAMDFGIPQ
                     KRERIFVVSCLGANNFSFNKLERKETRPLSEFFEKDVSELYTMTQPYMLKFLNKGIDN
                     SFRGRLKVIKDFSYTISTKQMRVPNSGIIDIGNGQYRYLTERECLRLMGFDDSDINKL
                     EEAHPRRKNCTSSKLYKQAGNSIVVDILMAIIKEIHRMEV"
     gene            complement(116202..117923)
                     /locus_tag="PC465_000532"
     CDS             complement(116202..117923)
                     /locus_tag="PC465_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HDF2647863.1"
                     /translation="MKLVIAEKPSVAVTIAKVIGSRTRKNGYYEGNGYIVSWCVGHLI
                     QMASPERHDEKWKKWSIENLPIIPEEYIYEVSKSTKKQYGILKKLLNDKNIDTVINAC
                     DAGREGELIFRLVYNQAKCKKKIKRLWISSMENKAIEDGFRNLKEGENFEDLYRSASA
                     RAIADWLVGMNLSRLYSCIYKETYSVGRVQTPTLYLIAKRDSEINLFKKKKYYTVDLS
                     YKGLKLVSDRIDRIEVAEQLLNLLEDEIVITEVEDKEISTKPDKPYDLTTLQREANKY
                     FGYSANDTLNLAQALYEKKLITYPRTDSRYLTDDMVTTMKELLEGLEEDFKINESNFK
                     SIFNSSKVTDHYAIIPTISGIGKAKDLTDKESKIYNLIKDKLLASCSDNLKESSRKIR
                     YEYDKFNFNASGKTIIDEGYTKYLKSYGKEKQKNELPDIKTGDKIKLTSKNISEKFTK
                     APSHYNEDTLLKTMENAGVESLDKAIEVERKGLGTPATRAGIIENLIHKDLIRRDKKN
                     LLVTEKGNRLVSIVEDKFKSAETTSEWEMKLAKISSGEVDKEDFLREIEDSIKELVDR
                     YKNNLNE"
     gene            complement(117987..118850)
                     /locus_tag="PC465_000533"
     CDS             complement(117987..118850)
                     /locus_tag="PC465_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HDF2647864.1"
                     /translation="MNKSIKRGVAIALLLFTFTVPATTFAMTNEGQIESQNESIYEPQ
                     KEEFEKMLKDDVFTPSKEEIPYQDVPRIPGNTSEATKPSNNPPKKTPLVKGGNTKAVN
                     SLATQENKARGSVIENVDRNGKDITPSGDTEKDKENPVDVRQFLTFQTKSGKTMHLIV
                     DHSSNQDNVRLLTEVGEQDLLNMIESEDKNTIKVEEPKKEEVKKEEPAVVPVKEEKKS
                     GIGSFLIVALVIGGVIGAGYYFKVVKAKEDKMLEDFEEDDEYISESEDESDNEESHEE
                     SLDEDDEDELL"
     gene            complement(118865..121216)
                     /locus_tag="PC465_000534"
     CDS             complement(118865..121216)
                     /locus_tag="PC465_000534"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019450.1,HMM:NF024702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat protein"
                     /protein_id="HDF2647865.1"
                     /translation="MKKFNTNRLRAFFMALLLVLTSTVHTSAFAKSDVTWTEDDFMYS
                     SEGNIIAFSDKGLEKKEKTNILVFPEGTKSINGNYSLSHSNDELRYKREFGRGKHWDK
                     VIIPDSVKHLGYAAFYEASIDQVKLSNSLTYLGGLAFFNCGLREVTLPDTLVNIEHNA
                     FERNNLQEIIIPKSVKTIEQYAFSRNKLHTIKVLGNPNINSKGVFHNQDVEYRPKQNP
                     FYENHFGFNGNQGFKSIPNGLRFENGEFVFDKNVDSVELEFDYNNDMYQGKMTIYNPN
                     KYSVDTQTDLTGQDIDEKDNKIDDLTKNIKDLENQIKDLNDKKQEDQSKIDELKAKLE
                     SCKDNGEKLKQEKAKLEEEIRDKDNKIAQLNKEIEELKNSNNDELIAEITQLKDELKR
                     LQDENAKLKEDYSSTKWELEAEKEKTDKNENKVKEMQEKLESLEGELAKKTKEIEDKD
                     NKIKGLEKALDEKDNKIKDLESKRKETENSKSECCKKIEELQKAIDSLKESSENTKKE
                     LEEKIKGLEEKQKAYEEEIKKLKEELDKKIEEAKKLIEEANKKAKEELEKQTKDDKDK
                     NLNQDLSKKLDELLKLQKENKEKKEDKKSQDKKWDELLKADDKNILNQFDLNKMKKQE
                     EQQNKKQVKDEKEFAVFQVDKNFYNIINKDGKTTVYMDVKTYVDQGRTMIPVRYIAYT
                     LGFNVEYDNSTREAIFSNKENNILAKKTLRLNIDTGVMKDSDGKVYNSDVKPVIINGR
                     IHASISNIAKAFGASHGDIKDGKNQTIEWDNARKAVYVFKNVK"
     gene            complement(121203..121442)
                     /locus_tag="PC465_000535"
     CDS             complement(121203..121442)
                     /locus_tag="PC465_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001080402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647866.1"
                     /translation="MNRKLISIRNKKKKIEEKLKDLNAKYKEICDEEIQVENEEIIVT
                     LRRNNISLEELMEKINDRKREEKLKEKENIHNEEI"
     gene            complement(121457..124036)
                     /locus_tag="PC465_000536"
     CDS             complement(121457..124036)
                     /locus_tag="PC465_000536"
                     /inference="COORDINATES: protein motif:HMM:NF013073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2647867.1"
                     /translation="MDKKLKKDFQKKIIRNRDAPEKNIDSKLVHSDDYTNKIIKTKDR
                     FGDKISEKESKLIHENVLAKDQKQDKLKDFQKAKNKERIRKEVLDNKDKAGETKQTNL
                     EMRTDESFKLDEDLDVDFKKVNFDSENSRNINSNKLTTDDISAKAQPISNKKASSKRQ
                     VLKNYEDKLIHSKDKFQDKINEKESKRIHTSEDKPIEAKKSKRIYRKDKLVKDEVSKN
                     ESNTNINKKQKQKLYQEKKFRDKEKISKEIDKENKLSEVDTDKTFDNSELKDNNKEFI
                     KDEKETSLKPSEQKKVNKKKTYYKRKNYESDKFTRKKIDDLKNESKKVTRKDSKKAQD
                     VKDFISDKKIGELEKSKSKLKDNILKNKTKGSLSSGVLLSGAKSSELVRDYLSSGSDN
                     TGVESGEKAANVSSKLQHGIRKYKLDKKKKSLKKLSKLDKKIRKRKSKLEFKSGLEDL
                     KKSESYIKKNRFKKFYQRKQMKSMIAKKHETRLVDRVKKAILSLGKASKELIVRKSKM
                     VLFLVIGLGLMLSIMIGGGSVGMSGLSNSVNSVMTTTYLSQDTILSEVNQEFSSMEYD
                     LQSQIESVKTSHPGYDEYIINKEGEIGHNTHELLSYITSRCGEVKSASEVKGILKDLF
                     DKMYKLDFKEEIEIRTRTVARTRYDSRGNPYTSYEKEEYEYKKLIVTLKKKEMDEVVR
                     EIFKDYPDNVVHYEALLEAKGNMGDVFGSGNWDLGEIVDNPNFGNPGLAFDSATAKAL
                     FNEAEKHIGKRYVFGASGPSNFDCSGFVCWSFTKSGVKRMPRTTAWRIYKDYCNPVSP
                     SEAQPGDIIFFHSTYNSGTPISHVGIYAGNGMMIHAGDPIQYTSINSKYWKSHFYGFG
                     RPR"
     gene            complement(124044..126467)
                     /locus_tag="PC465_000537"
     CDS             complement(124044..126467)
                     /locus_tag="PC465_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002836672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2647868.1"
                     /translation="MKQRKKQISDLNLREKQLKKDRKEVRRLKTKKDPTNSLLSVILK
                     KEKKRFTVEDTIPYIRMLPEGICQLDEKNYSKTISFQDINYQLALEEDRDLIFNQFAN
                     FLNSFDPSVHIELSYVNQLGRNRELQDAIKIADKGDFYDDVRKEFREMLKLQLAKGNN
                     GLKKMKYITFTTEADNLEQARAKLNRLEVDILSNFKSMGVRAESLDGEERLRLVHDML
                     NPDKNFDFSYKDLKKKESTKSHITPNIFNFAPANNFKFGKFIGAVSHFQILASELSDR
                     MLSEFLDIDDNIYVAFHIDVVEQAEAIKLIKRKNTDLDRMKIEEQKKAVRAGYDMDII
                     PSDINTFGADVKSMLSDLQNRDERLFVVTIVMMNFARTNQKLENTIAQISSIANRHNC
                     QVKRLSHQQEQGLVSVLPLGVNQVEIKRFLTSSSTAVFMPFTTEELFIDSANSLYYGL
                     NALSQNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMANAILVTDDDVIICDPEGEY
                     SNLVKQFNGEVIKVSAKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGSGL
                     TAAEKSVIDRCLPKIYQKYFEDPKPENMPILGDLYYMLLSQEEGVGRKLATEMEIYVK
                     GSLNVFNNRSNVDLNRQLLCFDIKELGTQLKKIGMLVIQDQVWNKVSLNRGNKSTRYY
                     IDEFHLLLKDPQTASYSVEIWKRFRKWGGIPTGITQNVKDLLTSQEIENIFDNTDFVL
                     MLNQASGDRDILAKKLKISPYQLNYITNSNAGEGLLFFGNTIVPFIDKFPKDTMLYKL
                     MTTKPEEAK"
     gene            complement(126358..126768)
                     /locus_tag="PC465_000538"
     CDS             complement(126358..126768)
                     /locus_tag="PC465_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012797153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HDF2647869.1"
                     /translation="MAYVPIPKDLDKIKTKVAFNLTKRQLIGFSVAGVIGIPTYLFMK
                     KYLPNDVSIIVMLIVTLPIFFITLYEKDTLTFEKYFKFFYLHKFYQPTKRIRKEAYLE
                     AKKKANQRLKSKGKTIKKRPKGSKKAKNKERSNK"
     gene            complement(126770..127060)
                     /locus_tag="PC465_000539"
     CDS             complement(126770..127060)
                     /locus_tag="PC465_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647870.1"
                     /translation="MLKKKNCALLGLGILLGGTYEILKEKKRNEEIRNLKRRINRLGR
                     CHNEFVMYQGEYNDRNEEKQEELEERISYLEEETTSNYDHILELSKKEVEGD"
     gene            complement(127070..127933)
                     /locus_tag="PC465_000540"
     CDS             complement(127070..127933)
                     /locus_tag="PC465_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647871.1"
                     /translation="MFGIFDKLTEFFKDMLLGGIKANLESMFLDINDKVGVIATDVGK
                     TPMGWNGEVYNFIKKINDNVIVPIAGLIITAVLCIELINMVMQKNNMHDTDTFEFFKY
                     IIKMFIAVYLASHAFEFSMAVFDVAQNLVNKAAGVITTSATVSGDQIVAMVDTLKEKD
                     VGALIMILVETSLVRIAIQCISLTITLIVYGRMFEIYVYSSVSSIPFATMGNKEWGQI
                     GTNYIKGLFALGLQGLFLMVCLGIYTVLIRTVQVTDIHASLFSILGYALLLGLMMFKS
                     GTVAKSIMNTH"
     gene            complement(127944..>128030)
                     /locus_tag="PC465_000541"
     CDS             complement(127944..>128030)
                     /locus_tag="PC465_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2647872.1"
                     /translation="QGIKQLMAGGGIVLIGIKLIPLLANALK"
BASE COUNT        40611 a        22811 c        15897 g        48711 t
ORIGIN      
        1 ttcaaatgtt gtatttgcaa ttgaatctgt agctcctgtt ccagatactg ctcctgcttt
       61 aactagcaca cttacattat ttaaatcatt ttgtattgat tggcttgctg ttcctgatac
      121 tgtaattgtt attgtatttg ctgatctatt tcctactgct gtataatcta gtcctgatgg
      181 taatcctgct actttaacat tagcttttac atctccatct tttactgtcc catttgttaa
      241 ttttagtata tatgtgttat ctgatggatc tactgtctta tctcctgatg ccatttttat
      301 ttgtttatct gttgcactaa attttatttg acctaccttt gatgaagaac ttcctccact
      361 acttcctcct gaagaacctc cacttgatga acttcctcct gatgaattag aacttggact
      421 atttccactt attgttggag aattatctcc cttaacacta cttattgtac ctttattatc
      481 tatagtagtc cctttagaat tatttgtaac tgtagttatc ttaccaccat tagtcacttt
      541 tacttgactt gctccagatg ctactgttaa actaccaatc tcacctttag aattattttc
      601 tatcttggct ccatttttat cattaacctt taagttagtt atttttccgt agttaacaaa
      661 agttccatct tttacatcat ctataactac atcatccact tttgcatagt tatttacatc
      721 accattaggc atgttgatag tcacagtctt tgtatatgta ccatttaagt ttactgttac
      781 tgctttatca gtttgtattg taaatgcttc tttaacctca ctagttggct taaagtttat
      841 aacatcatta gcagtagctt tatctatagc tgattttaat tcagaaattg ttttagcttc
      901 aactgttttt acttcttgta atgacttcat ttcattaaat gctgtctcat taccattccc
      961 accaacttta gttatcttat caaaactctt agagttaact agagattttt gtgaagctga
     1021 taagttcttt ccaactaaaa ctactggtga ttgattttta gcacctaata cacctactgc
     1081 tagtgcatct ataagttggt cttgtttatt cataccatct ttagttacat aagcattttt
     1141 taaatctgtc tttttataaa attcttttat tacttttgca tttgtatcat ttctatctgt
     1201 tccacctagt cttgtactat ttggtagttt atttttaaca gcttcagaaa ttgaactctc
     1261 tccacctact acataagatt gagttattcc agcatctttt ataaatttgt ctgcaactgc
     1321 tgttccattt ttagaatcag caagtattac tggcatattg ttttgtgcag ctggtgctcc
     1381 tacacttaca gcatctgcaa gtcctttttc accattaact acagctattt tcttaacatc
     1441 acttatagca tctaatttct ttgctaattc taaggatgtt tgatatctct cagctccaga
     1501 gattctctca aaagatattt ttaaatcttt tatttctttt tctatatttg tacttaatac
     1561 agaagttcca cctattaagt atactttttt agcttttaat ctttgtattt ctgctttcgt
     1621 cttatcattt aatttatctt tacttgttaa aagtattgga gcattttttg cttttgcaaa
     1681 tggtgttgca gatagagcat ctgctataga tgagtcgttt acgattacta cctcatcagc
     1741 atttttccat ccatcttgac ttattttaac agcagtttca tatctttctt gccctgttaa
     1801 atttgttgcc acagtttgtg cactagctat gcctgctgtt gaacttccag ctatcattgt
     1861 aactgtaagc attgcagcaa tcttctttgg tattttcatt ttattttctt cccccttgtc
     1921 catttgatat tacttaattt tttaactttg ttcccgttct aattctaaag gatacttaat
     1981 atctaatttt aaagaggttt ctaactataa tgatttcata attaatttgt aattattttg
     2041 ttacattgca gtcattatgt aaggaataaa gaaattttct tattgattga aaaatttgta
     2101 aatttatatt ttaaggtaag tttgattttt atgttaatga attgttataa aaaatagggt
     2161 tttgtataaa aaaagtagcc tttagaatta aaagcgctac tctttttaca aataaatttt
     2221 attatttata cttgtaatta tatattaaat aaccaatttt atccatatga aaaacaaata
     2281 attgcgatat ttttttaatt attctttata tttacatttt aattcgaatt acttttataa
     2341 agattatatc tgttgcatat actactttaa gtgctaatat atctccccct caattagaat
     2401 cctcgttatc tcaatagacg ttttctactg tcaaagttac caacatttga aacttattaa
     2461 atttttatat aaaaaagacc tagaatataa attccaagtc attttttatt aaatttattt
     2521 tttacaatat aatattgtca tgattaaaga acacaaatca tacacaaatt ggtcataaat
     2581 cttacataaa tcatctacaa aaaatacatt atttatatta aatctatata actaaattaa
     2641 gagcatattg tacaatatgc tcttagaaaa gatatttctt gtttatagtt tatagtattt
     2701 ctctatgatt tttattttta tcatttcaaa aataaaaatt aagattacag ttattatcat
     2761 attttgtgta ctattttcta taatattata atgaaacaat gaaaaaacaa taattaatga
     2821 aattacgttt atagccccag aaatcaaaaa tgcctttttc ttattattta tatattccct
     2881 ctccagatta tctaaattag tctatatcaa gcatttttaa gtacttatca ttaactttat
     2941 atatattttt ttctttagac aaaatctcta tcccttcaag attattaaac acttccatca
     3001 actggtcaac taattcaatt tcctttattc cagcctttaa gtatctactt ttattctttt
     3061 ttatataatt ttctaatgtc atagaatagt tatctttatt gcaaatatat tttaatatat
     3121 gttcttctgt tgctgataga gttatgtcat tttcaaacaa ttcttctttt aatatacttt
     3181 ctaaagattt tctatcatgc atattacgca tctcattaat agattgtatt atagacttga
     3241 gcataaactc tataaataca gttaaattat ttcctttgtt ttctacatca agtatagcct
     3301 tataatactt agttctgttt ttagatatca tatatgatat tgaaaactcc ttgaaagtat
     3361 catatccttt atcaatcaaa tatagatatg ataaggctct tgatgttctt ccattaccat
     3421 cactaaaagg atgaacatat acaaagtaaa aatgaattat agcactttta attaaattac
     3481 ttactttgct attttccata aaatctatta atttactcat aaagtcatat atcttcaaag
     3541 gttcaagccc tatatgtata atctcacctt ttgaatcaca tacatatact ttttcagttc
     3601 tatactcata ttcttctgaa tccaagcagt tttcgcccaa tatatgatgc aaatcatata
     3661 taaatttgtg actatataat ttatctaagt tgtctaatcc atattctaag gctctatgat
     3721 tattgtaaat catatattca cttttattac taggtttcat ctttcctcta attatagatt
     3781 ttgcaatctt tctatttgaa aaagcacctt ctattacact agaataataa gactctagtg
     3841 ccaaatcatt tttatcttct attattttaa atatcttact tgatgttaat ttatctattt
     3901 catttattaa atttaatata ttttcagttt catgatagta tagttcttta ttatcaaaac
     3961 tatttataga aagtacgatt ttatttccag taaagtattt gtttttgtat tcttctattg
     4021 tcagtttaat caccacctta gattatcttt atctattaat attaacaaaa agtattaatt
     4081 tttacactat ttttgattat ttgttttata attatcaaac tcaatttagc gttaaagcat
     4141 aataaatttt aataaataat gcaaaaattt aagaataagc atttaaaata tatggcacag
     4201 gaagtttaca actattattt ataatacatt agttacatat tataatatct cgacaatgtc
     4261 ttaacaatat ctcgattata tattttaata tgtaactaat atgttataat attttaatta
     4321 aattaaataa atttatattt ttttgaaatt acttaatatt ttatataaaa atgaaaaagc
     4381 acctcattct gattaaaaat ctttctgaga tactttttaa aatattaaat actacatata
     4441 gcttacataa gtttaaaatt taatctatta taaaattacc ctaattgcca aactttttaa
     4501 tataaatttt ccaacatcct acaaatataa tcaatagata tagaatccta acttacacca
     4561 atatatattt atttaaaata gtcctaaaat acctgtaata gctcccacta ctatcagtat
     4621 aaacattatt tttattggag aaagaccttt ttttaaagca aagagtacta ataaagtaag
     4681 taccaaagga attaatcctg gaaatatctt atcaagtaaa tccgtttgaa gactaaattt
     4741 aaaatcacca ctagtataac ttattggtgt agataaatta ataaacctac ctacaagtcc
     4801 ccccatgact aaggtaccta gtatagaagc cccttctata accttattta ctattccacc
     4861 ttgaagtata ctttcaacag cttttttccc atacttatat ccatttgtcc acattccaaa
     4921 agaaattgaa gtcattatta tatattgagc tattacaaat aatataggtc ctgcaattga
     4981 tgctcctccc tcagttaaac caatacaaac agccaacact ataggagtta taactccttg
     5041 agttaaagta tcgccaattc ctgctagtgg acccatcaag cctgttttga tagcattcat
     5101 accatctcca cttatttcat ctgctccatt agctttttct tcttccatag ctattgttat
     5161 tccatgtata acacatccac atataggttc tgtgttaaaa aatgctagat gagtctccac
     5221 ttcttgtttt aactcatcct tatctggata taatttttta agtactggca acattgaatg
     5281 tgaaaaagct gttgattgca atctttcata attgtaatta gattgtgcaa agaaaaacca
     5341 tcttaaccat gattttatta catctttctt gcttaacgtt ttcttagata cttcattttt
     5401 tatatctgac ataatatttt ccccctcaca tgtatttaag atgtagcact atcttttccg
     5461 tacttaattg aagtaattgt aagagcaagt attactccaa taacagatat tactattata
     5521 tctactttaa aataaacagc cattagtatt cctaatatga aaaaaggcat agtaaacttg
     5581 tttccaatca attttaaatt catagcaatc ccaagtgctg gcaacatagc cccaattaca
     5641 ttaaatacat gtaacacatt atcattcatt acttccaaca taccatctat cgcatttgga
     5701 ccaaaataaa caactaataa tgctggtata aaactcattg caaataacag tatctgtggt
     5761 ggtactatat ttataaatgc tactctatca acattccctt tttgaacctc tctatcagcc
     5821 caatgtgcaa aaaaagaatt tactgtcatc tttccaatcc aaagtacagt tgcaacagtt
     5881 cccaatggta cagctattgc cattgcagta cttacatcta gcttagatgc tatagctaaa
     5941 gcagtaccta catatcctgc aaaagctggg tcccccatct gagctccccc tgctgatata
     6001 aagcctagat atatcatatt tatacctgct cctataattg ctccttgaac agggtctcct
     6061 aatataattc ccgttacaaa tccagccaat agaggtctat tccatgtaaa aaatccaaca
     6121 taagtcaacc acggactcca agaaagataa taaaaaattg ctattaatac tgcttgaatt
     6181 agtgaaatgt gcatattctt cctccctatt ttcttttaaa gatttacaag atagtcttct
     6241 ttataataat gttcctacat caattttctt tgcatctggt actatttgta taaagcattt
     6301 aacatctttt gatattagct ctctaaatat ttctttttct tcatctgaca cagatatatt
     6361 tttataaaaa ctttttctac caagccctgc tcccatacct ccaacattca attcctttaa
     6421 atctaccccg ctatttacta aacctaagac agttttaggg tatttgacca atactattaa
     6481 attttcatct ccattatgtg attttaagac ttcagcacct gattctacat catgtacttc
     6541 aaccttaaca gttgatggag ctgccatttg taaaacttga actataaatg ggtcctttac
     6601 tactaaatca tccacgatta ttatcctttt tgctgatgta atcttacacc aagcagtaat
     6661 aacttgccca tgtattaatc tatcatcaat tcttgttaat gctatattac tcataattat
     6721 tcctccagat ttttaattta ttttacaact ttaaaacagt tttaacatct ttgattcctg
     6781 atatcccaac ttcctcacat aaattcttca agtcttttaa cttcatagta tctctgttta
     6841 aaaataactc taaaagcata ggtaaattta cacctgtcaa acattctaac tcacatacct
     6901 tagcaaattt atttattata atagcagatg tattaaatgg agttccgcca taaaaatcaa
     6961 gcaatactaa aaccccttca tccttatatt tctcaattcc atcttctaac tttctactaa
     7021 actcatctat gctgtcacca tggtttaatc ctaaagtttc tacattttcc tgtttgccta
     7081 ctattaattc agcactttct aacattgctt tagccatatt tccatgtgtg gctataatta
     7141 ttcctgccat atgaatcata cctttcttaa ccttttttat atggattatt atttagtact
     7201 ctaatctaat tatctatatt aatcattatc ttaccaaaga aaatatccct tttgtatact
     7261 ttttcaaaat aagctggtac ttcttctaaa tttattctat gtgttactaa tttttcaaca
     7321 ttcatatcac ccttttgcat atgatacaat ccagcactcc attcttttcc tgggaatgga
     7381 aaggagtttc caaaccaaat tccctttaca gttaattcac ttcttactat cttttcaaat
     7441 tgctctctag tcaaagctac atccccatat ggtacacctg catacaatac tgtacctccc
     7501 tttttagcta gcaacagtac ttgaccacat gtcagtggag taccagccga ttcaataaca
     7561 atatctgctc catctccatc agttaacctt tttatttctt ctacaatatt cttttctttt
     7621 gcatttatac aaatatctgc ccctaactct tttgccaagt ctaacttctc atcaaataca
     7681 tccacagcta ttacttttgt agaaccaaat atttttgccc attgtattga aaataatcct
     7741 attggacctg taccaagtac tacaacagta tctccaactt tagcttctga cctaaaaaga
     7801 ccatgtcctg ctatacatac tggttctagt gcagcggcag tctcataact tatctcatct
     7861 ggtattttta ttaaatttct ctctttcacc tttgtatact ctgcaaaaca acctccaagt
     7921 tctttatttc ctattattgc tacattatta catcttgaat acaagccttt tttacattca
     7981 tcacattcaa aacatggcat agctggacaa acagcaactc tatctcctat tttaaaactc
     8041 cttacttctt taccaacctg tgccacttct ccagaaaatt catgccctaa aatttctcca
     8101 accatatgtg gacctgtctt tgaatatttt gatatatcag aaccacatat tccagctact
     8161 tttactttaa ttattacatc atctttttct aatatttttg gtacatccac atcctccact
     8221 cttaagtctc ttataccata gaatctaact gacttcacta ttaaccaccc ctacttttta
     8281 tttgagaata tattcctatt gtttatatgt taaatatcta aagcaacttt catgccaata
     8341 tatgtaagca ttgtattcat gcattttaca aaattatcat taaatgtgtg tcaaagtgtg
     8401 tcaaaagttt cttatattaa aacttatgtg tgtcaatata aacgacacta acattttata
     8461 ttagttctct tattataagt tttataaaat gtactttttt tgttattttt ataaaattgt
     8521 tcggaaattt cccttctatt tgtgatataa tattaaatat aaggtatcaa tataaatttt
     8581 catgcgaata tcagaacttt tttgacacta atgccttatt caatataata atttaacttt
     8641 ttggaggttg tttatgaaaa aagtgtatca aggaaagact aaagatgttt ttgaattaga
     8701 taatggaaat tacttactta aatttaaaga cgatgtaact ggtaaagatg gagtatttga
     8761 cccaggcgaa aatagtgtag gtctaagtat agatggaatt ggtagagcta atttagagac
     8821 atctgttaag ttctttgaaa ttctaaacaa tgctggaatt aaaactcatt atgtaagtgc
     8881 taatttagaa gaagcaacta tggaagttct accagcaaaa gtttttggta atggattaga
     8941 agttatttgt cgttatagag ctgtaggtag tttcttacgt cgttatggtt catgtgttga
     9001 agaaggtgct aaactagatt gttatgtaga agcaacttta aaagatgatg accgttgtga
     9061 ccctcttata acatctgaag gtttagaagc tttaaacatt atgactcaag ctcaatttga
     9121 ttcaatgaaa agcatgactc aaaaaatttc taacatagtt cgtgatacta tagctgaaaa
     9181 aggtcttgag ctttatgata ttaaatttga atttggattc tacaatgatg aagtaatctt
     9241 aatagatgaa atagcatctg gaaatatgcg tgtctataaa gatggtgtaa tagttgaccc
     9301 tatggattta actgctcttt tattagataa atagtatata catataattt acaaatataa
     9361 taaacttata aataagataa gctatgaagt aaagactttt taaatgttga ttatttttaa
     9421 acattttctc gcctttaatt tcatagctta tttaaattaa tatactctaa ttagtagata
     9481 atagctttaa ccctacaatt cccaccacaa taaaacctat acatgcaatt cttgatatac
     9541 taataggctc atttaaaata gccatgccta caatagctgt accgacggta ccaattccag
     9601 tccatattgc atatgaagtt ccaagtggaa gatgttttag tgctaatgac aaaaaataaa
     9661 aacttacaat cattccaaca acagtaagta tacttggagt taatttagaa aatccatgtg
     9721 aattttttag ttgaaaagcc caaaacactt caaacaaacc tgcaacaaac aaaaataacc
     9781 atttcataaa ttcatccctc ttttcaaata tgtctcttat ttttccaata aaataacctg
     9841 agaaatatta taaaatatct cccaggtttt tgtccttccg tgttcacaac aaaaactatg
     9901 ttgtgggttt tatctcggac cagaccaatc attaataatt gcggaaccct ataaaactct
     9961 attaattatt ctattttatc tataataata ctatcaacat atataaaaaa agtcaatata
    10021 tgggttccat ctataataaa aataactttt atataccttt taatattctt attcacttct
    10081 ctccataccc atttaggtca atctaagaat atctaatttt tatttaatat gttataataa
    10141 cataaaaata ttgaaaggag taatttctat gaatttctat aaaattgcag tatgtcagat
    10201 gattactaca gaaaataaaa ttgaaaatat caatcatgct gtagatatgg taacagaagc
    10261 tgccatcaat ggagctaaaa ttgtagtttt gccagaaatg tttaactgcc catatgaaaa
    10321 taaatatttt cctaaatttg ctgaagaata tccaggtgaa acaacaacga tattaagtaa
    10381 attagctgag aaacatggaa tttatctagt ttctggtagt attcctgagt tagaagatgg
    10441 aaaaatctat aatacttgct atgtatttga taaaaatgga gctctaattg gaaaacatcg
    10501 taaaatgcac ttatttgaca ttgaagttac aggaaaagtt agttttaaag aatcagatac
    10561 tcttacagct ggaaatgatg tcactgtaat agataccgaa tatggaaaag ttggtatagc
    10621 tatttgctat gatattcgtt tccctgagtt atcacgttta atggctctta aaggtgctga
    10681 aatcgttatc ttacctgctg catttaatat gactactggt cccgcccatt gggagttatc
    10741 tataagaatg cgtgctttag ataatcagat attctatgtt ggtgctgcac ctgctagaaa
    10801 tatgaatgct tcttatatag cttttggaaa ttcaagaatt tcagaccctt ggggaagaat
    10861 aattgctcaa gctgatgaaa aagaatgtat tatttatgct gacattgata gagatttaat
    10921 tcctgacata agacaacagt taccacttct taagcacaga agaactgatt tatatgaact
    10981 taatactttg aaataaaaca gaacataacc ccataaatcg taaattaagt gttaaaaaaa
    11041 tttatggggt tctcattaat ttgatttaaa attaatttca taaaaataat gctaaaatta
    11101 atttaattaa ataatactaa taattactaa tgattatgct aattatcagc atttactaat
    11161 ttaatcacta ttagttattt cttttattaa atatctttac ttttttactt attatgtctt
    11221 ctagctttac atttggatta tggtatttct ttctattttt agtcacatct ttctattgaa
    11281 ttacttgctt aaaacaccaa tgcacacatg ccagataatg ttcacaatta tgtagaaatc
    11341 ttgctctacc ttcttcaatg ttgatattat ctctcctagt tgatattatc tttcctaaaa
    11401 tttcttttaa ttaaaaaaca acattagttg atatatcaag tatattttaa gcaactgaaa
    11461 aaaacaataa taattgatat atcaactaat taatgtagat taattcattt ttataattta
    11521 tatacttttt aattaatcta ccttatttaa ttaaaatcct tcctttctat ttatccattt
    11581 tcaacttaaa ttataagatt tcatcagcta tatttttgca taccaataag tattaaatat
    11641 caaatatata ttctattaaa atttctaata atttcatcct tgatttattt aatatataaa
    11701 aatatactaa ctttaatgat taagttttga aatataacta aaaatttgat aatttattga
    11761 gatttttata ctaaaatata catactatac aaacttaatt tagaagggag cattcttatg
    11821 aacaataaaa tactcgtcgt agatgatgag gaaggtataa taacactctt aaaagattac
    11881 tttgaaatga atggttatga ggtttacact gctcaaagtg gaaaagacgc attaaaaaaa
    11941 atatccaaaa atccagatat cattctactt gatataaaca tgcctgaaat agatggaatt
    12001 gaagtttgta atagaattag agattatgta tcatgcccta ttctatttct tacagctaga
    12061 attgaaaaca ctgacaagat aaatggtttt cgtgctggtg ctgatgatta tattgtaaaa
    12121 ccttttgatt tagacgaact tggagctaga gtatctgccc atttaagacg tgaacaaagg
    12181 aagtcaaatc aaactaaaat taaattttat aatgatttaa caatagatta cgaaaaaagg
    12241 ttaatttgta tatataataa tcagatttca ctttcaaaaa aggaatttga tatagtagag
    12301 cttctctcta tgaatcctgg acaagtattt gataaagaaa aaatatatga tagagtctgg
    12361 ggatacaata gcaatggaaa tagtgatgtt ataatggaac acattagaaa aatacgaatc
    12421 aaactatcaa aacatactct tgaaaattat atagaaacag tctggggagt tggttataaa
    12481 tggataaaat aaataatatg tcattaaaaa aagctttctt tgttcttact ttatcttcac
    12541 taattatagc atcagtactt actactttcg catacatttt acttaataat ctatataatt
    12601 ctatacaaga taagtattta aaaacaccta taaatacagg tattataacc atagttcaaa
    12661 acaatgtgaa ccaatttagt gattatgata aaacattact taatataatc aacatactcc
    12721 agcttgtact tccacttata ttttttatag gacttttatt attagctgat ataatttttt
    12781 acaaggtaaa attaaaaaca cccatagaaa tactcaataa aggtgcaatg gaaatatcca
    12841 acaacaattt agacttttgc ttagaatata ataataatga tgaattaggt aatctatgta
    12901 atgcttttga aaaaatgagg tctgaactaa ataaaaacaa cataaagatg tggactatga
    12961 ttaatgatag aaaacaactt aatgctgctt tttctcatga tttaagaaat cccctaacag
    13021 ttctaaaagg ttactcaaac tatttaacaa aatacatacc aacaggtaag cttagtgatg
    13081 agaagatttt atcaaccaca caacttatgt ctgagcatat taacagaatt gaatactatg
    13141 tagaaaatat gagtaatgct caacgattag aagatttagt tgtttcaaaa tctatgtcga
    13201 atataaacaa gtttatagaa aacttagatg aaaatatatc tatcattgct aaacaagaag
    13261 gaaaatcttt tacacttaaa aatcaaataa ataatataaa tctatttttt gatgaaaata
    13321 tcattcttag agtcgtcgaa aatataatat cgaatgcttt tagatatgct agaaataatg
    13381 tatccatact tatatatctt gaacaagaac tccttacctt tgtaattgaa gatgatggta
    13441 taggatttag taaggaatct ctaaaattag ctttaagacc tttctataga gataagactt
    13501 taaatgacag caatgcacac tttggtatgg gtctttatat ctcaaaaata ttatgtgaaa
    13561 aacatggtgg ctctatttct attgaaaata attctactaa cagtgctaaa attactgcta
    13621 aattctcaac aagaaattaa aatgattttg taagctttca ctgctattat ataaaatttg
    13681 ttagtttaga atttataaaa tgtatttcaa tttacaacca atatatatac tattttgtag
    13741 aagttgtaag agttgcttca attataatat tttggcaaaa ggcatttgaa acaataatag
    13801 aaatatatat ttaaatatgt agaatagtat gaaattagaa ttttggaggt gattatatta
    13861 aaagttttgc taataatatt acattctctc gtattgtgtt tgcattgcta atgcttagtt
    13921 ctacattctg ttcactgcct ttctggatat gttatttttg gtgtggaatt agtgatatac
    13981 ttgatggtct tattgcccga aagttgagac aacaaagtgg aataggtgca aagttagata
    14041 gtattgctga tttcattttt gcggttacaa ttttggttac tgtcggaaaa aatattgctc
    14101 ttcccatgta tctatggtgg tgtattgttg caatagcatt gttacggttg attagttaca
    14161 gtattggttt ttttaagtat cgcacatttt catcgcttca tactttgatg aataaaatca
    14221 ctggaatttc tatctttgcg tttccattac tctatatttg ctttggtctt gatgttgcag
    14281 gaattatgat atgtatcgtg gcttttcttt cttcttttga agaaatagca attatgataa
    14341 aatcaaaaga attaaatcgt gatataaaaa gtatatttat gtgacaactt agaatttgtg
    14401 acaaaaataa tttatataat aatgaggaag taaaacataa aaaattatcc acaagtttat
    14461 gtgtaaaata gttttaaagc aatagagttg tattgtaaag cctttagtgc ataaattaca
    14521 ttttaaatta aaaatgatac tgaaactgct tatcagcact gcgaattatc cgcaaatagt
    14581 gaagactttt tagatttaag ctaaaagttg ggaaaaaatt gagttttaaa acttacactc
    14641 ttcttatata gaaaaggaga gtgtttttta tgattataaa agcaaaacaa ttatcaaaaa
    14701 tatatggttc taataacaat aaagttatcg cacttaataa tgtaaattta gaaataaact
    14761 caggtgaatt tgtttctgta attggacctt ctggaagtgg aaaaagcaca cttttacata
    14821 ttttaagtgg attagataat cctacctctg gacaagtgtt acttgatgat aaagatatat
    14881 ataaacacac tgaaaaagaa ctatctgcac ttagaagaaa atcctttgga ttcgtctttc
    14941 aacaatttaa tcttttacct gttcttacag catctgaaaa tatttcaatg cctgtacttc
    15001 tagataaaaa acaacctgat aaaggctatt taaatgaaat ttcatcatta cttggaattg
    15061 cagatagact caatcatctt ccccatgaac tttcaggcgg tcagcaacaa agagttgcaa
    15121 ttgctagagc acttattgca aaaccagata taatatttgc tgatgagcct acaggaaact
    15181 tggacagtaa aagtggcagt gaagttatga atcttcttat aaaaacttca aaacagtttg
    15241 gaaagacttt agtggtaatt actcatgatg atagaattgc aaaacttgct gatagaaaaa
    15301 tttcaattat tgatggtgtt cttatggagg tgaaatagaa atgaagaatt acctttcact
    15361 ttcaataaaa gaattaaaaa gccagaaact tatgactaca ttcatcatta tagcaatagt
    15421 actatcaact attatgacaa ctgtggttgg acagtcaatt ggtatcctac aaaatttaag
    15481 aattgaacaa gcccgttctt ttaatggtga tagacatgta tcctttcacc aactcactaa
    15541 aaatcaagtt gatgacataa agaaagatga tagagtttat caagctggta cttcaataac
    15601 tattggcagt agtaaaataa aggattctgg tatctctgta cttgtaaaag agtatgataa
    15661 aacaggactt tctaactacc ccaaattaat gaaattaaaa tctggacatt tgcctaaaga
    15721 taaaaacgaa atagccttag atgaaaacac actaaagctt atgggtataa aaccaagact
    15781 aggagtgact atacctatga atttagatat ttcactttta aatgatacca taccaccata
    15841 taattacaca gctaacttta aattgagtgg cattttagag gatgattata caggatatgt
    15901 aagtggtata gtaaatggta ttgtaggtaa aggtacatca gaaaatctat tacctaagag
    15961 atatatttta tcctctttgg attttaaaat aaaacagcaa gaaaagtttc aagaaatagt
    16021 aaatcaatta gctaaaaaaa taaatctttc tcacaattca attcaatata attggattta
    16081 cttaaatgct cttaagatac agtttgaaaa agatgaaaat agttctaata gtgatggtat
    16141 atctatgatt atattggtat ctttatttgt tgccttattg gttttactgg cctctggact
    16201 tgtaatctat aatattttaa aaatctctgt tacaaagaaa attaaagagt atggatgttt
    16261 aagagcaata ggagctgaac caaaccagat atataagata gttattttac aaatcttaat
    16321 tttatgtact gttgccatac ctattggagc tgtaattgga attatatctt ctaaaggcat
    16381 aactggaatg gtcactaata tcttaaatcc agatatactt ctagcaaatg ataataaaga
    16441 aattactgag cttatacata aaaatacaac agcatatatg ttcccattag tattaagcac
    16501 taatgtatct ttgatttttt catttatttc agcattacca tcagcaatat atgcttcaca
    16561 tgtctctccc aaaattgcta tggttggtag taccaccaaa atcaaaagaa aaattaaaag
    16621 agaaaaaaca ataaaaaact ttgaaagaca tctagcatgg ctaaacttaa aaagaaataa
    16681 aggaagaact ataataacta tactatcatt atttatgagt ataacagtat tcgttgcact
    16741 gagtgagttc tctaatgtat tagatgtatc taggtcagta agtaatttaa aagaaggaga
    16801 tttttcctta acaaatgaaa tatctggttt tgataaatca acactagata aaataactaa
    16861 aatgaaaaac gtcaatcgca cttcctttat aaagtactct gaatacaaac agggggaaat
    16921 agatacagat ataaattttg aaaatagtgg tgagatgtta aaaatcattg gaattgatga
    16981 gcaaacttta aaagacttaa tgccttctat tacagattct atactagaag actttaaaaa
    17041 tggttctatc tgttttataa aaaatccgat tgctatttct acaccaggtg taaaaactag
    17101 acatacaaat ttaaaaccta aagatagtat cacaatcaac aaaaaacaac tagatatata
    17161 tagtacagta gataaaatgt tctttttaca aggtaatggc tggataaatg gtgttgatgt
    17221 tattgtatat gattctgttt ataacacctt gacaaataaa aacaaattca accagataaa
    17281 tatttatgct aaagataaat caaaattaga acaaatagga ttgtctatcg aacagatttg
    17341 tgaaaataat cctggctctc attggatatc atatattgaa tcagataaac aacttaaaga
    17401 gagttttaaa caaatagaat ttctagcatg ggcagttata ttatttgtgg gattgattgg
    17461 tactttaaac atcattaaca caactcatac aaatataaat actaggacta atgagattgg
    17521 agttaaaaga gctattggta tgagtaatag tagcttatat aaaatgtttt tatgggaagg
    17581 tgtttattat ggaatttttg ctgctatatt tggttcaatt gctgggtatg ccagtgctat
    17641 tattataaac atggcaacta tagaaaagct tgatttcact aatataccaa ttacttcaat
    17701 tttacaagct actattattt ctgtacttgc atgtattata gctactctta ttccgttaag
    17761 aaaagttaaa aagatgaata taattgactg tatagatatc aatttataac tattttacag
    17821 ataataatat aaattaaatt atcaatgact gtctctattt tctttcaaat ctaactaata
    17881 aatcttttta actataatat aagctttaaa aaaggcctgt ctcaaaatag agataagcct
    17941 tttttcattg tcgaaataat gaaaatatat ttaacttcac aaaaaaagag tgcctcacga
    18001 attaaaaatt tcgctttgag acactcccct ttaatttaaa atatatagtt aaatgctatg
    18061 ccaaaatttc acacatgctc cacctgattt tgaattttct attttaacag aacctccaag
    18121 ctgttccact aattgtttga caatgtaaag cccaagacca gaatgtccac cttttgtctg
    18181 cctagcttca tctcctcgat aaaatttatc aagagccttt tttaaatctt tagagctaaa
    18241 ccctctacca gaatcacaaa tctcataaga aatacaattt ttttcatcct ttacagtaat
    18301 actaatatta ccacctgatg gagtgtattg cagactgttg gatatgatat tatcaaaaat
    18361 tcgtgtcaac ctatccacgt cgatttgaat tggggattgt atattcccct gcattttcaa
    18421 tataagttca acttcctttt gatgagcctg taattcatag tcttgcacct tttgcctcaa
    18481 aaattcaggt aaatttatag gaacaagatt taattgtata tttgactttt ctaagtcaga
    18541 cgtatattgc atcttttgga caagagcagc acttttttct gtattttctc ttatcactgt
    18601 aagataccta tgaagttttt cattgtcatc tgtattatta ccaataagtg catctgtata
    18661 tcccaaaata atagaaagag gagattttaa atcatgtgct agagcttcca ccatttcaac
    18721 acgttcctgc tccatcttcc actgtgcaga taaagagcct tttaattcgt ctttcatttc
    18781 agaaaaggca ctacaaagtt taccgagttc attatctgaa taatagtcga tttcaaaatc
    18841 aaggtccttt tcttttatct tcttggacgc atcaatcaat agatgtaatg gttgattgat
    18901 attctttaca aagcgcttag aaagccatct agtaaaaccc acgatatata gaaatggaga
    18961 aaacagagcc attataataa ctgcaaatac aaatctccct ctaatatttg caaaggtgat
    19021 tttcacttgg tagaatagaa taacagcacc ctcaatcttt ccattatccc ctttgattgg
    19081 aacagtatgg atataaccac ctttacgaac agttttattg atattattat taaataattc
    19141 ttcttttgtt ttaaatagtt ttttggggtt agtaccatat aaaatattgc cattattatc
    19201 cacaacttga tatagcatat catccccacg aatcgttctt tttaaacctt cttcattcga
    19261 ttgtgataac aaagctatgt ttttttcatt gatgtatttt tcaattctag gaacttgtcg
    19321 ctcataatag tttggtggat agatatcctt atttaaggaa tgaatataca aatagagagc
    19381 aaatacataa gtaatcactg tggcaactat actggctatt ataataaaaa taaaagtatg
    19441 tctaaattgg gtaataaggg attgattttt catttaataa cctctctctc tttacatttt
    19501 attccactta tacccaatac cccaaactgt ggaaatatat tctttttctg gtgtcacagc
    19561 agaaaactta gctcgtattt tttttactcg ttcaacaaca gttgaggaat caccttcaga
    19621 atcacacccc catacttttt catagatttg ttctcttgag aaaacttgtc ctgcatggag
    19681 tgctagtaat tcaacaatat catactctat ttttgttaaa tcaatattct taccatcaat
    19741 tttaattgca cgttccttca tatataagca taacttccca aaatacaaag tagatctctt
    19801 gttctcttca ttgatatact gtgaacgctt ttccctacgc agattagctt caatccttgc
    19861 cataagttca cgcagtccaa atggctttgt tacataatca tcccctccaa aggtcaaccc
    19921 tttgattttg tcggtttctg attgctttgc acttaaaaat ataattgggc ataaaacatc
    19981 atctctaatt gcctgacata cctcaaatcc attcatttta ggcatcataa tatccagtat
    20041 aataaggtca ggctcctgtt ttgataactc tatacctgcc tgaccatcat aagctatcaa
    20101 cacttcatgt ccttttgcct tcaattcatc ctcaagtagc attactaggt ccatttcatc
    20161 atcaataatc aatattttac tcaatataac accacctttc tcttatggga aggtcagtat
    20221 taaaacaata ttcgtctact cataactttt ccttccctcc cacattttaa accaaataac
    20281 gcctcctatc aagaatataa tcaaacctat tgctactact ataagctcta tactagctgt
    20341 ttgcatcact ttagagtaaa atgcctcagt tgaaatagtt ccagcttctt taataaaata
    20401 aattcctgga agcataccta gttttactgg ccatgtccat ggaacaaatg cccatacttt
    20461 ttcaccaacg ctagttaatc caagtattgc tgccatcaaa attccaccaa tactaatacc
    20521 aatagatgca cccatacccc atgcaaaact cacccaaaga tgaatagcta atagtggaag
    20581 tgtcccaatc accacaagtc ctgctgctga caggaataac catattgttg ctccagatgg
    20641 cactgcaata ctcattccta tgcaaagtat caacgtagca ataaatgtgc atatagttag
    20701 gcaaaacaga agaaaaagaa attttcccag atataatctg acacgagaaa tacctacaca
    20761 taaaaaacca ttaaaatttc cagcaagctc ttcctcctgc actataaatc ctgctaaaat
    20821 acctactcca ataggaatga tgaatacagt ccatactgta aaaaatcctt caaaagcaaa
    20881 ttcttgtgta cttccagatt tagttgtgag ataaaaaacc acacataatg aaaaaataat
    20941 aggcatacaa agagtaagcc actggacagc tgtcctcttt gctcgaagcc attctgatga
    21001 taatagtttt atcatttgtc atccctccta ttgaaccaag ctgcagtaag tgctgttaat
    21061 actataaaca caaccaaaga aacaacaatc ccaataggaa tcactgaagt attcaaaagt
    21121 gggtctccag cttctaatat agtaccgtta ggatgtatgt tgatgattgg gcataccatt
    21181 ctaactgccc aactccaagg tactgcaatc caaaatggtt ttgtcgcagc aagaacacca
    21241 aatatcatac ctaaagctcc aactcccata cttaggaaca tacctttcca tgtagctagc
    21301 catagctgaa gtggaagtat agcaagagaa acaacccagc atacaatact tgcccctata
    21361 atctgtccaa aaggaactgg accagctttc aatattaaac cagttataat tgttacgact
    21421 attaaaacta gcgttgaaat aaaactgtag actgccatag ctataacttt attaatccaa
    21481 agtgtcatag gagacacatt gtgtgtacgt aaagcacgat aatttccagc ttttttttcc
    21541 tggaaagcta ccaaagtagc gaacaatgca aatccaatag gcagaaataa aaatgaccac
    21601 cagttaaaaa ttaatgctaa aagattttgc cacgcccaag aagttgtttg agataatgga
    21661 ttttgcatga gtgttgattg cattataaat gcatatgctg caaaagacac tgggaaaaaa
    21721 acaataagtt tacccataaa tgttctttta tactttaaaa gttctgattg taaagcattc
    21781 atctgttttg tcctccttta agaataacat ctgtaaaaaa ttcttctaga ttttcattag
    21841 ggtcaggcat tccttgaaat aatagtcgtc ctccatttat aattcctata ttatctacaa
    21901 cttgagcaac ctctgataga atatggctag aaagaattac agttatacct tttttgggaa
    21961 aagaagcaat caattcacgc aattcttgaa tgccaaaggg gtcaagacca ttggttggtt
    22021 catctagtat taacaactct gggtcactca aaagtgcaat agctattcct aacctttgtt
    22081 tcatacccat agaaaattgt gaagctctct ttttacctgt atttttcaaa tttactattt
    22141 ccaacacttc ataaatttta tctttaggta ttcccaatat ttttgtatgt actaacaaat
    22201 tttcctctgc tgtaaggttt ccatacaatg caggggattc tattaaagaa cctatttttg
    22261 caagagattc tcgtttccaa ggctttctat caaaaataat acgaccattt gttgggcgaa
    22321 gaagaccaac aagcatttta agtgttgtgg actttcctgc tccatttggt cctaaaagtc
    22381 catatatact atttcgttca atttgtagag aaacattgtt aactgccatt tgttctccat
    22441 atctttttga taagtttttt gtttcaagaa ttaaatcttt catattaatt tctcccttct
    22501 tgtaatacct taaatctgtt actaagagaa tactaacatg aaaaaataac aattctataa
    22561 cacctactaa ttttaataaa atttaaaata aaaaatagag ttaccaattt tattttggca
    22621 actctattta agtttatgtt ttacagttat attagattta agcttagttt cattatcaca
    22681 ctaacttcaa atttactcta taatccttaa atcaaacact aatttattaa tcaaacacta
    22741 atctattaat ttatatttct ttagacatct aatatagttt gctactaaat aataattatt
    22801 tatatcatat ttatctaatc ctttaaaaga agttatttca tcattaagct catcactacc
    22861 ttctacaaaa acataacctg tttcaaattc catacctaca ataatcttac agccactata
    22921 aatttcctct tgagtatcgt acaatttttt tgcatttcct tcatttggaa ttgtaaatac
    22981 aataggtttt aattctttat cactggaaat cttttgtgaa aaaggcttgt ttaacttaat
    23041 attattgata actacatgtt taaattcctc tgaagtttct tctactatta catattttcg
    23101 ctttaaaaac tctattattt ctaaaacaga cttagaattt acttttaaaa tacttttata
    23161 tttttcatat aaagatttcc actgttcaat tttttcctgt ggtatttctt ggatatgtgt
    23221 acttattttt tcttgagata tttttttcaa ttaaactctc ctttcaatac ttaaatattc
    23281 ttatgaatct cacatgacta aagttacaag gtttctactt aatagaattt tgcatactta
    23341 aatatgtctt attaattctc tacaggatat ctccgtagtt cctacaattc ttacataagt
    23401 tacttatttt aaattgttat tagttagatt ctaaaaatta tttattttat cactaatata
    23461 atactcttaa aaactttaca aatcaattta aatttgctac cttttattta taacaactta
    23521 tagtacattt ctcctatgct tttcaatata ttacttttaa aaggaggttt tccttatgat
    23581 tttaaataga gctgagcttt tccgaggata ttctttaaat agatttaacg agatatgcaa
    23641 tatattatca gtaaataaaa ttaaatataa gtataaagtg aaaaataatg cttactctaa
    23701 aaaacctttt tttaatgaaa taacacttgg caatttaggt caaaaggaag atttctctta
    23761 tgagtactta atttatgttc ataaagacga ttatgaacag gcagagtctc taataaattc
    23821 taagttgcga tagattattt ataaaacatg acattctgtt gtcatgtttt atatgttatt
    23881 atactttcaa atatgctact atattttcaa aattgtgtgc tttaaaacta gctttttata
    23941 gtaatttaaa gcttaaaact aaggagactc gttatatgaa aataaatata aaatcaaagt
    24001 taagtgaatt tattaaacag aacaatcttt ttgatgacag cagaataata tcctaccttc
    24061 ctaatataac aatagaaaca gacaaaataa aaactataat gattaatgag gttgtcccaa
    24121 ctaacaccaa tgacgatttt tatagtgtag ataaagatgc tgattattta aaaactacta
    24181 ttcctttatt tgacagtgca ggaataaaag tatctaacat aaatgatatc ctagatatgg
    24241 gtatctatat aactaatgca gtaaaacttc ctaaatcaga atatacaata actcgtgata
    24301 caattaaatt acatatgcct attttagaag aagaaattaa attatttaaa aacctagagg
    24361 tagtaatgtt aatgggagat gttgcaaaaa aatcttttaa tatgattact aaaaagcata
    24421 taaaaaagaa tgtcatccct tccatttcaa catataaact tcgtaataat gaactttatt
    24481 atgataattt aagagtattt ccatcatata ttatgactgg tggaaacata ctgattgaaa
    24541 aatcaaaatt tgaaatggca tcagaagata taaaaaaaat gttcgagatt ataaacggtt
    24601 gatattacaa aataataaaa actaatataa aataaaagtg catcaaaaac ttctatttat
    24661 gaggcacttt tattttatat tagtgtaact atatactatt aacataattt attatttata
    24721 ttgttctttt taatctctat tccatttagt ctaggtaaca ttactcttta caagattact
    24781 ttatatttct tttatatctc taacgttttt atttaataaa acaattatta atacaagtca
    24841 aatatatcta tttatctaaa aatatatctt ttacagtaat atctggatgg tgatacttct
    24901 tcctattcgt taaaaaagat ttttttacat taatagcctc ttttggacac cagtgaaaac
    24961 aagctaggca tctttcacac tcattacccc actttggctt tttatcaact atacttatat
    25021 tctctacagg acaaaccctt ttacatgtcc cacatccatt acatttattt tctgcaaaaa
    25081 atttagtagt tgcaatttgc atattcttac ctactaaacg aagtacaaca ctatctatat
    25141 gtgactttaa attgtttttt ccttctatat ttccaatctc caagttattg atacattttg
    25201 caatctcagc taccctatta gtctgatttt tcaatctttc ttcttcaaca tctggaggtg
    25261 ttatcaaagc atttccaggc atattgatta aaaaaccagc agataatttt ttcccccttt
    25321 ttttaagtaa cttatctata gtaaataaac tatgtccagc taccccatta caagtggcaa
    25381 tggcatatat atgagtatta atattaaaat ttaatttctc tacaaaagac tttactatat
    25441 caggaacatc agcaaaataa acaggaaaaa caattaccaa tatatcttca tttatgtcta
    25501 tattattttc ttttctatgt atagctaagg gtataacttc tttacttcca tttaacgttt
    25561 cttttaaaat atttgaaact actagcgaat ttcctgttcc agaaaaataa taaatcttac
    25621 tattcattct tatccctctt tctatatttc tacatcatca atagttaaaa agtctcttaa
    25681 aataggattt atatttactt tccaattcta tccaaaatat cagtaaacaa aggcaattct
    25741 tcatcagaga tagatttaaa tgtctctgtt gcatatatac ttgcaatttc atttaatggt
    25801 tcttctaatt ctctacctaa atctgttagg aatatttgaa acttacgtct atctttaaca
    25861 tctactttac ggacaattaa tcccttattt ttcataacat ctaagattct tgtcgtatta
    25921 gatttatcct tacatgattt ttcacataaa tctatctgag aaattccatc ttgctcccat
    25981 agaaacctta ataacgcata atggtcagtt gttatatcat atccattttg tttaaacatc
    26041 ttttttaaat catcttttac ttttaacgaa gtacttacta acttagttgt agcttcatat
    26101 agtttctcaa aatctttcat tttacctcca tttaaataat cccttgctcc tcccatctat
    26161 caattattcc cttatattgc tcaatatctt taaaagccat tggctttaaa acagcattta
    26221 tagcaataaa attatagatt tgagaaagca caggtggatt tttcttttcc tctatgcaat
    26281 aaataaattt tttagatacc ttttgtatct ttgattctac tttttcagtt ataggatttt
    26341 gattaaatcc agtttttata gataaactac cacaaacata acctcccgaa tctaagacca
    26401 tggattttat aaaagaaatt gcttttgaac cacgtgcatt ttcatatgta gtaactgcta
    26461 tacatggctt acgatacaat aatctttcaa gcatcatatg tgctctatct gtaaacacct
    26521 tgaaaagtcc agttacacta cttccataag ttgggctacc aaatataaca ccatcactct
    26581 tagtaattat atcatgaata tactctactt tatcattttg attgatacac ttgcccattt
    26641 tataacaatt taaacaacca atacaatatg atggatttac cttacttaaa tcaaaataat
    26701 taatttttac atctggtatt aatctttcta tatctttata caagtaagtt aaaacttttg
    26761 atgtagctcc attttttcta gggcttccat ttataactgt aattatcatt tctatatctc
    26821 ctttttagtt gttatatcaa caataagtat atcaactata tttttagctg tcaatataaa
    26881 ccatttattt aaagctatac ttacacagct taaataaaag ttttatttaa ctacatgtgc
    26941 ttatttaatc aactataaat gaattatttt taataattga caaactaaat taatgataat
    27001 atactttatg tattacaaat gtaagtagaa ggaggtatag tatgaaaaag ttaccacata
    27061 tttcagaagc agaatatcaa gttatgaaaa ttatttggaa atatgctcct atcagcacta
    27121 ctgaagtaat tgaaaagttg gtagaaacaa gtacatggag tcctaaaaca attcaaacaa
    27181 tgttattgag attagttaaa aaaggagctt taacatatga aaaaaatagc agagtattcg
    27241 tttatactcc acttgttaaa gaagaagaat acgtagctaa agaaagtagt tcttttttaa
    27301 atcgttttta taatggtact cttaattcta tggtactaaa ctttttagaa aatgataaac
    27361 tatctgaaga tgatattgag gaactgagag aaatcttaaa taaaaggacg actaaggggg
    27421 ataaataaat atgtatgccc cattctttat acgattttta ctcagtacat taaccttatc
    27481 aatattaatt gctgtaattt tacttgccaa aaaagtattt aaaaaacata tttctgcaaa
    27541 gtaccaatac aatattggat ttatattgct tataatgtta ataattccat ttgtccctct
    27601 taaatatatt aatcttggaa atgtatttaa ctatttatat acttttaatc aacttggaag
    27661 cagtactaat aggacttcta tgataaaaaa tagtccaaat tctataatta ataactcaaa
    27721 tgcattaaac gatttttcag tatccctaaa ccaagttaat tttgatagtt taaatatttt
    27781 attactaata tcatggataa ttggaatttt aatcatgata gctattacta ttcattgcaa
    27841 cattaaaata aaaaatatga aaaaatcaat acaaatttta agagatgagg agatagtatt
    27901 tatatttgaa aagtgtaaaa aagatattgg tataaataag gattttatac tatgcaaatc
    27961 acctattata aatacaccta ttacatttgg atactttaaa ccacacatta tattaccaga
    28021 taagtctata tctaaattat ctttaaaaga tataaaatat atcttacttc atgaattaca
    28081 acactttaaa aataaagata tactgataaa ttatataatg tgcttccttc aaatattata
    28141 ttggtttaat cctcttgtat ggtatgcatt taaagaaatg cgtatagacc gtgaaattgc
    28201 atgtgatatt tcagttttaa aaaagcttga taaagatagt catatagaat atggacaaac
    28261 tctaataaac tttgtggata atatttcaag accatcaaat cttacactta catcagatat
    28321 tggtgggtca aaaaaacaaa taaaaaagcg actattgaag ataatggatt ttcataatga
    28381 atcaaatacg ttaaaattca aaagcatttt aatttttaca ttgatagctt taattgtatt
    28441 tggaaatatt cccaaactat ctattatggc agatatcaac gaaaaatata gacctacaaa
    28501 tgaacaaact gtgtacgagg acttaagtca gtattttaaa ggttttgatg gaagttttgt
    28561 tatgtatgat ttaaaatcca agcaatatca tatttacaat aaagaaaaaa gtaaaacaag
    28621 aatttctcca aattctactt ataagattta tagtgcctta ttgggattgg aaaatgggat
    28681 aataacaaga aataattcac atatcccttg ggatggaaag catcattcta atagttcttg
    28741 gaatgaagac caagacttat tttctgctat ggaaaactcc gtaaactggt actttcagac
    28801 tctagataaa aaaacagggc taaaaaacat acaaacttat cttaggcaaa ttggatatgg
    28861 caattatgat gtttcaggtg gtatctcaaa cttttggcta gaatcttcat taaaaatatc
    28921 acctattgaa caggtagaat tacttgaaag tttttataca aataagttta aatttgaaga
    28981 taaaaatata gaaacagtaa aagattcatt gttaatatca aaaaaggatg gggtatcact
    29041 ttttggtaaa acaggcactg ctaatataaa tggaaaagat gtaaatggtt ggtttatagg
    29101 ttatgtggaa aaaaatgaaa atacttattt ctttgctaca aatattcaaa gcaaagatta
    29161 ttctaatggt agttcagcat ctaagataac attatccata ttaaatgaca aaaaaatcta
    29221 taatccttaa tatatttact gtacattcta aaaaattcac ataattttca tattaattat
    29281 caattaaatt catatacaag gcttattata taaacataga agatagtaaa actagcttaa
    29341 aaacataata taatacccta tacaaatagt ggcaactctc cctcacatcc tcaattgttg
    29401 ccactattta attttttgta tgaagttaaa tatattttca tcatttcaac aataaaaaag
    29461 aggtctatct ctattttgaa acaacctctt taattatttt agagtttact aagaagtcta
    29521 aaaacaattt atctaaaata ttattctcaa ctgagtaaga ttaatttcca aattgagtaa
    29581 atttaatctt caaacactga tttaacaata ggaataacat aatgacttcc cccacgactc
    29641 tttacatctt caatcatagc aattactata tattgtttat cactattttc atctacagta
    29701 aaagcattaa accatccaag ttctgtccct gtaacatcat cttttgatgc tttaatttct
    29761 gctgtaccag ttttcccagc aatgctaatt cctttaatca tagcactatg acctgtacca
    29821 tcagggcttt caacaacttg aagtaagtca tcacgaataa tttttacagc ctctttagaa
    29881 aacacacctt tcttccaaaa ttcagccttt ttaaattcaa gatggggttt tatcatgtct
    29941 ccatcattta caaaagctga atatattgat gccgtatgta ctggatttac aagaagctta
    30001 ccttgtccat agccagtatc tgctaattgt atttcagtct caaatttatt gtcagtgcca
    30061 aattttgaag aagacaatcc aaattcaaat ggcatacttt catcaaatcc aagcttcagc
    30121 aactcttttg ctaatacatc ttcacctatt tttaaggctg ccttagcaaa ataaatattg
    30181 tcagaataaa tcaaagcatt tttcatattt gcagtatttc cataatcttt taacgtggtt
    30241 accttataac ttccccaact agaatctttt tgccaactta gactgctgtg tccaaagttt
    30301 tcatttggat taatctttcc tgttgttata ccaataccag cagtaactgg tttaaaagaa
    30361 gacccaggac ataatcgtgc tttaaatcta ttgtacattg gtttattttc atttttattg
    30421 agttcattcc atctatcttc tgacattccc aatataaact catttggatt gtacgacgga
    30481 ctacttacaa gtgataaaac ctctcctgtt ttaggattca taactactgc acaaccttta
    30541 tcatttttca tttggtcata tagtttactc tgtagttttg aatctatagt tagctttaca
    30601 tcttctccat ctacctttgg ctcagttact aaagtttctt tcttgtcacc atatctatca
    30661 gctattataa tctcatatcc atcaatacca cgtattctat cttccagtaa attttctaaa
    30721 ccaatcttac caattatact attatcgttg tacctcttac cctctttttc ctttagtata
    30781 tctgcattta cattttgaac ataaccagtt aaatgaccgg ttttttcacc aaatggatat
    30841 actctaacct ctgtattaga tattttaact ccaggaatac taagaagtga ctcttgtagt
    30901 tccttatctt cttcttttac agtaccatct gtattttctt ttattttttc aatagttttt
    30961 ataggtacca ttgaattttc ttttacccaa gatgcattta atttcttttc aatttgttca
    31021 actgatacat tcaataaagt agataatttt tttaagtctt ctatattatc actcattttt
    31081 ccaggaacta atcctatcat agatgcaaga ccttgaccag caatcattac accgttccta
    31141 tccaggatac gtcctctctt acctttcagc tttgataccc ttacagtatt atcttcttca
    31201 agttctggaa atatgacgtt tgactgccat tttattttat aatttttctg tctatctcta
    31261 gttaatagta cttcatttga aaatgaaatt tcacctgcta aagtatccat cttagaatca
    31321 tagtttatta ctttatcatt atttttattt tttttaatat cattaatctt aatacttata
    31381 tcgtgtgcat caattccttc atagattttt ttatttctta aaacaaaatc ttctttttta
    31441 ttttcagact tgctcttttc atctaataaa tcatacattt tctcatattg ttttttattt
    31501 gcaaaagaca tatactgctt aaacacttca tctggtttgt ttttattgag tccatctagt
    31561 atgaattttg ctaaaaaaac aataataact ataagcagac acattagaaa accaaaaatt
    31621 atcatttttc ttgttttttt attttttctc atataaacca cctttatcat ttaatatatt
    31681 acatacgtaa gctttaaggt taaaatactc ttatagacat aactaatcta tgtttttatt
    31741 atgtttttaa gtatctcata aaaatatgta agcagtataa ttgatagtaa cttatatatt
    31801 acacatgtaa gttttaaaag tcaataatat tatcattatt taattatttt ttacatcaac
    31861 ttaaaaataa atcagttcca ttatattctt ttgtattctt caactatttt ataaattaac
    31921 cttattctat tgtaattatt ttatagtata taactttaac ttgacaaaac gacacaagtg
    31981 tctcataatt aaaagtgaca cttatgtcgt taaaaaggag gttaaaacat atgccaacaa
    32041 aaggagaaca aactaaacaa tttatcattg atacatcaat aatgctattt tctgaaaaag
    32101 gatatagtaa tgtgacaatg aaagatatat gtgaagcatg taatttaagc cgtggtggcc
    32161 tatatagaca ctttaattca ccaaaagaaa tttttatcag tatattaaac actcataaat
    32221 actactctca aaatttgttg gataaaggta tcaaggaaaa tatatcagct aagcatatgc
    32281 tagaatattt tttccaacaa caaaaggctg acataaatgg caaatattgt ggatttgatt
    32341 ttgcaataca cgaatttgct tttgtagaaa aagaccaacg tgattatatg aataaaagat
    32401 acagttcagc tatcacaatg ctttcaaatt taatcgatta tggacaatct aaaagtgaat
    32461 ttaaaaaatg tgattctaaa tcagttgcaa tacacataat gttcttattt gatagcatga
    32521 aaacatctgc ttccattttg aaacttacaa ataaagacat tgataatcaa ataaatatta
    32581 taaaggacat ggtgatttta tatgaataaa caaaaattcc ataaaattaa tttacaaaac
    32641 tgggaacgat atacacattt ttactacttt tcaaaaatga caaatgtagg gtttaatttg
    32701 actatagaaa tagatattac taatttgctt aaggaaacga aaaaaagaaa tattaaattt
    32761 tatccagcgt atttatatac aataactact tgcttaaatc gatatagaga actaaaaatc
    32821 gcatatgatg aagatgaact cggatattgg aacacgttaa cgccacttta tgcgattttt
    32881 catgatgata ataagacttt ctcatcaata tggacagaat atgatgaaaa tttctcaata
    32941 ttctatgaaa attatttagc tgatgttaaa gaatatggaa aaaatcatgg ttttctagca
    33001 aaaccaaatc cgccaagaaa ctgctatact gtttcctgcc ttccatggat tagctttaag
    33061 agttttactg tacataatca tggtcttgaa aattattttt tccctacaat tgaagcaggt
    33121 aaatactatc aaaaagatga aaaaatactt cttcctcttt ctataacagt gcatcacgca
    33181 actactgatg gataccatgt aagttgtttt attgattaca tacaaaaaat gtgctttaat
    33241 actaagatat ggctacacta aaaatttata caatataaaa agaactgtcg catgagcaaa
    33301 ttaaatttgc tatgagaaag ctctttttta cttacaatag ttaatatgag atgaattatt
    33361 tcttatactt tgaacttacc aatagttaat atgaaatgaa ttatttctca tactttaaaa
    33421 agattgaatt actcttgata atcttctttt gtagtcatta catatcacct actactcaac
    33481 acatattctt tgacctattt ttacatcctt gtttatatcc aaaatattta ccttcttacc
    33541 atctggaaac aataccattg ttaaagtaga ctttcctaat tcgtgtattc tctttaaatc
    33601 aacattaaca agaacgtctc cctgtttaac catatctcct tgtttaacag caacatcaaa
    33661 gccatctcca tttaatgcaa ctgtatcaat tccaacatga attaatactt ctccattagt
    33721 tcctttaatc ccaaatgcat gtccacttga aaatactgtt tctaatttac ctgaaatagg
    33781 agaaacaatt tttccatcta taatatcaat agcaaaacca tcacctaaca tttttttaga
    33841 aaatgtttca tctggtacat tttctaatgc aacaattttc cccttagctg gagacacaaa
    33901 gttttcatta ttttcattaa acactaattc ttcgtcttca tcttcattta tagcttcttt
    33961 aggcactcca aataaacatg ttacaataaa gcagaatgca accacaaata ttgatactaa
    34021 taagtatgtg attaaattat atccatcata gatatacatt aaataagaag gtaaaactgc
    34081 taatccatat gaattagatt gaatatgtaa aattgataat attgctgctc ctaaacctga
    34141 agatgcacac ataataatca aaggctttaa attatatcga agctgaatcc caaataaaac
    34201 aggctcactt ataccaaaaa gttgagatag cattgctcca actgcagttt gtttaacttg
    34261 attattttta gattttttca taaatgctag acatgttcca atattcgcaa atccatacat
    34321 tgcacaaaga gtaataaggg cattaaatcc tgtatttgct aatagtgatg tttcaatcat
    34381 tacataagta tgatgtaagc cagtaataac agctaatgga tatgtaaatc caataataaa
    34441 tcctccaatt cctaaaggca aatcaatcaa taagctgatg atatcaacca tttttaattc
    34501 tattgtatgc attatagggc ctacacctaa taaaataact aacattgtta ttagcataac
    34561 aaagaatggt gtgaaaataa ggtctaatac attaggcata tgtttacgga accatttttc
    34621 aagattagct ccaataaatg ctgtaacaat agctgttaaa acacttcctt gacaacctac
    34681 aataggaata aatccaaatg ccataattgc ttcaatttca tttgatgggt cagcaacaga
    34741 atatgcatta ggaagtattg gggaaactaa cataagtcca ataacaagtc caataacagg
    34801 tgttcctcca aatactttaa atgctgacca tacaataatt gctggtaaaa aagcaaatgc
    34861 tgtttctgta agaaccgaaa caagtgtctg aatatacaat ggaatatttg cagaagacat
    34921 tccaaataat ccaagtacat tatcattaaa caaacaaccc tttaatccca agaataatcc
    34981 tgttgctgca ataactggaa taataggaac aaatatatct gctagagttc tcataacttt
    35041 cttaaatcca gtttcattat ttttaactaa ttcatcttgt tctttttttg ataaagtttt
    35101 taatcccatt ttttcaactt ctgcataaac tttattaact attcctgttc ctaaaataat
    35161 ttgatactgt ccagaagtaa agaaaacacc tttaacctca ttgacctttt ccactttctt
    35221 atcattaata gtttccctat ctttaatcat cacccttagt cttgttgcac aatgtgtaat
    35281 agaaataata ttatcttcac caataatttt aataagctca tttgctattt tattatattt
    35341 attcattttt ctacctcgct ttcaataata ctgcatgaaa tggtttcaaa cacactgttt
    35401 tatttaatag atttatatca tctaaatttt ggaatacaat atcatatttt tcttctactc
    35461 ttatttctac aggtttatca gaaaaattat aataacaatc aataactacc aaatctaatt
    35521 gccttctata cgcaataaca tcttcacttt ctatatcaat aggttctatt gaaccataaa
    35581 tcaaacaatc agaatactca ctatcttgtc tcaactttat catcttttta taaaattcta
    35641 aaatactctc tgaattgtta atctgactct gtgcattaat atctttataa ttttcaataa
    35701 cctttaacca tggtgttgta tctgaaaaac ctgcattttc tttatctgcc catggaaatg
    35761 gcgttcttgc attatctcgg cttcttaaat tcacaaattc taacgcttct tcttctgagt
    35821 aaccttcatc tattgaacga tagtattggt caatgctaga taaatcatta aaatcattta
    35881 tggtatctct tttaaaattt gtcattccta attcctgccc ctgataaata aatggggttc
    35941 ctcttaaaaa gaaatacatt gctcccaaca tttttactgc atcatcattc ctttcgtatt
    36001 gcaaaagata ctttgttgta gctcttggtt ggtcatgatt ttcaataaaa ttagctgccc
    36061 atccatgttc ctgaacatac atttgactat ctaaaatgca ttttcttaaa tctggaattg
    36121 tccatgaaat tcttttaaac cactcactac cagaagcaac atctaagtca gcatgtttaa
    36181 agtcaaagac cattgaaaag aaaccatctt ctccaataaa atcacctaac tggtcatagc
    36241 taatacctgc tgcttcagca acagtcatac aatcatattt tttaaacgta ttttctttta
    36301 attcataaag cattttttct attccaggct gatttctaac tgtttttgta catttaacaa
    36361 gaccatcaac accatcactt tctaaacttt gaaaacttaa attctttttg atgaatgtaa
    36421 tagcatcaac tctaaatcct gccactccca tttgagacca ggtattaatc atttggtaaa
    36481 gttcacttct taatattgga ttttcccaat taaggtcagg ttgtttttta ccaaaagaat
    36541 gaaaataata ttcgtctcta ttctctacct tttcccaaac acttccacca aaaacagacc
    36601 tccagttatt tggtaaatcg tttccttttt taaaaatata ataatcatga taaggacttt
    36661 ctggattttt taatgcttct tgaaaccaag gatgttcatc acttgtatgg ttaagaacta
    36721 aatctaatat aattttgatt cctctatctt tactttcttt aattaactct tttaaatctt
    36781 ccatacttcc aaattcactt gcaatatcca aataatcact aatatcatac ccattatcgt
    36841 ccataggtga tttaaaaatt ggacataacc acaatgatgt aatacctaaa tcttttaaat
    36901 aatctaaacg agaaataatt ccctgtaaat ctccaattcc atcattatta ctatcttgaa
    36961 agcttcttgg ataaatttga taaacgattt ctttttgcca ccatttcttt tccataaatt
    37021 actccttttt atatgatatt tcttcttttt aattctttat aaattccatt atcgaatatg
    37081 tcctcacata tagatgtcgc tatatcttta agttgttgat gactattttt cattgcaatt
    37141 gtaacgtctg atgcttgaaa catgacaatg tcattttgac catcaccaaa acatatggtt
    37201 tctttttgag ttactcctaa tctttcttgt aatctcttaa ttgctttgcc cttatgaaaa
    37261 tctttttgaa taatttcata atactgacta gaaatatctc tctgtgctaa ttccatttta
    37321 tcttgtagta tatctttcac ttcgtcaaat accttttcat ttgaccataa acaaatttta
    37381 tgtatatctt gtgacttata ctcttcaatg ttattttcat atgttatttt ttcttggata
    37441 tgttgtttat ttatacaaga attagttcct ttcaactgat tcattgtttc aaatatttct
    37501 ttggcttttt gattcatgaa aactttttcc tgactctcaa tcgaaaaagc aacttccctc
    37561 ttttttaata aacaaacaac ttcctttatc aatctttgat taaaagattg attataaagt
    37621 aattcaccat gatattgaat gtaattacct cctcctgcaa tatatccatc aactcctaat
    37681 gataaaacat catcttgtat tgtacccata cttcttccag tacaaataac aacactacaa
    37741 tgattctttt gacataaacg tatagcatgc tttgcagatt ctgggattcc atatacctca
    37801 tctctaagcg taccatctat atcaagtatt aataatttgt acaatttcat cttcctttct
    37861 tactatcaaa atcataatag cattcaaaaa aaaagatatc aatattttga tatcttttaa
    37921 aaaatatgtt catttttagc acaaattttc attttcgggg aatatgttca ctttctaaat
    37981 acatcttgta tttaatataa agcagttcaa ttaaaataaa ataaggtgtt gttacatcgt
    38041 agtccagttg tttatctaca gaaatagata tagattgaat atacaggttt tcatcacata
    38101 atcttgctaa aggattactt atcatttttg taatagaaac catataaatt cctttcattc
    38161 tcatttcttt agcaaaatca ataattgtag atgcatctcc attcaatgaa ataaagaaaa
    38221 tcatatcatc tgtttttata aaatgattaa gtgcctgaat catatcataa ccataaacat
    38281 catatataat tttccctgtt ggtaagaaaa tccttttcat ctctttagca actctttcct
    38341 gagaataacc ttctccaaag acgattatac gatttgcctt tttcattctt tcaaacataa
    38401 tcgaacaatc cttcttctct atatcatcta tcaccttatt ataacaatcc attaattggt
    38461 gtttactttg atttttatat tctacttctg tttcatttaa gcgtataata actcttaatt
    38521 cactatatcc aggtaattgt agtttttgag caaaacgaga aagtgcactt gtagatatat
    38581 ggtatttgtc tgcaaattca tctatagaaa gtttaataca atcttcttta tgattaagaa
    38641 tacactcaca gatatactta tcatttgctg taaatgaatt ataatattta ttgaaaagtc
    38701 cttcaatttt cattcttttc tccttctata ctctatgtaa ttcatatgaa gcaaatctaa
    38761 tagagcataa aatgctccta cgacttcata agatatagct tgtaatgtat caagtttttg
    38821 agtttcaaca tacagattat actcacaaag tgttgcaatt gtattattat caagcctagt
    38881 taaagaaatc gtatgtatat gattgttgat aaattttgca atttcaattc ctgcttttgt
    38941 ttctccagat aaagaaataa taataaataa atcacttttt tgaaatgatt ctctcataaa
    39001 ttcaatttca cctatatcaa ataagtcaat aacacattta cctactgaaa gaaatattct
    39061 ctttatttct tgagctaaac ttttctgttc attacctgtc ccataaatat aaattgtttc
    39121 tgcatcatat attattttac aaatatcttg aaatgatatt ttttgtaatt cattcattaa
    39181 tagtcgataa ttctcgcaaa catcatgaaa attattatca ttattaacaa attctagttg
    39241 attattttta agtaaatact ttaaatcaga gaatgaatct aatccaattt ttctacaaag
    39301 ccttaataaa gtagctctag aaacattaca ttcatttgca attttttcac acgaaaaatt
    39361 acggtattct ctttgacaaa tcaatatttg tttaataata attttatcat tttcatttaa
    39421 attatcataa ttttggttaa ctaacgattc taatctcatt ttttccactc cctaaatatt
    39481 attttaatat acattagttg ctttttctag ggaagagttt taaataataa ggataaaata
    39541 atcatttgat tttattttta ttaaaataaa aataacctgc taaaagcagg caccaaaaag
    39601 tacttatcct ttcgaacatg tactttagat attgctttct tcggaagctt catctcttca
    39661 tactctaaaa tagagttttt tctaactcaa aagtattttc catggtagaa attactttaa
    39721 ttcatctgcc atttattttt tatcttattt aataattact actacttgaa tatttacttc
    39781 tttaagtaaa tttcatagtt aacaaagcta aaactattat tatagatgtt aaaatacaaa
    39841 attgtaagta ttgttataaa tatgcttaca gctacaaata tacatgatat attaaaaaga
    39901 agctgtaaat tattatcata catacaagca actacgcctc tattaatcca tgttaatttt
    39961 tattatttaa tacaaggagt tccatgagac atacatatcc attcatattt taaattatcc
    40021 aattctctta tagatttcat catcttttta taatcccaat tccatggatt aggataagga
    40081 actatatttc cattcttatt tttgactaaa tcacctgcaa ataatacatc ttcaaaaatc
    40141 atgcagacat gccctggagt atgaccagga gtatggataa tttttatatt cccaatctgc
    40201 atattctctc cataaggttc aacatcctta atgagccttc tggaaattgc ctttccaata
    40261 aacttcttaa acccaggtct atccttctct cctataataa aaggtatatc ctctacatga
    40321 gcccatactt ttgctcctgt tttttctttc aataatttaa tattagatat atggtcaaca
    40381 tcatgatgag ttaataaaat atgcttaata tctgtaagtt taataccaag tgtttttaat
    40441 tctttaatta tatttttccc cataaaagga agacctgtgt ctataagaat aatttcttta
    40501 tcaaacacaa taaaacaatt tgagccacga gtactatcta acattaatac attttctttt
    40561 atcttcataa ataaattccc cttatttggt attttaccta tataattaat taataaagtt
    40621 ataaatagtt ataatacttg atattaattt tattttttat taaagtatac tataggtata
    40681 caagtattat atttacataa gtataccatc agtatacttt tttatcaata gaaaggaata
    40741 atttatatgt cagaattatc aaaaagagat aaagaaaaaa tacaaagaga aaatgagatt
    40801 attgataagg cagaaaaatt attttgtctt aatggatttg ataatacaac tatgaatgaa
    40861 ttagcaaaag aagttgaata tactaaacgc accatataca agtacttttc atgtaaagaa
    40921 gatttattct ttgctgttgt cttaagagga tataaaagac tttgggataa tgttaaaata
    40981 gaaagtgcaa aaggcaaaac agggtttgaa aaaataaaac tttcatactt tgcttttcat
    41041 aaattttact ctgtagaacc ttctctatta tgccttatgg gaatgattgg tattgtaaac
    41101 tctgaaaaat cggatactga tatgctgttt aaagaaaagt ttttttcttt taataaattt
    41161 atgtttgatg aaatacaagg aatgtttgaa attggaaaaa atgatagaag tattaggcat
    41221 gatattgaaa tacctactct tatgtattca tcaatattta cacttacagg attttttaat
    41281 ttactatctg taataggaaa atcatacctg aacaacttta atatagatga ggaaaaattt
    41341 attgaaacaa ctcttgctct tttaatagat tcaattaaag cataaaccta agtttataaa
    41401 ttaaagttta tatacttaaa tttaaatgat aattttttct atctctaata taaaaaatat
    41461 taaacataaa actaataact tagttaatgg aataactaaa ttactgaaag gattaaaagt
    41521 aaatggctaa aatacttctt ttagaagatg atgatacaat tacatttgga ataaaaactt
    41581 cccttgaaaa gaaaaatcac actgtatgtt gttataatac gattgctgaa gctaaaaaaa
    41641 attttgataa aactattgat ttaattctgc ttgatttaaa tctacctgat ggtattggat
    41701 acgagttttg ccaatatgtt aaaagtatag aagatactcc agtgatattt ttgacagtcc
    41761 gtgatgatga aaaagacatt atacgtggat tagatatggg tgcagatgac tatgtggtta
    41821 aaccgttttt gctctcagta cttcaatcca gaattaatgc agttcttaga agaactcatt
    41881 caaatactaa caatactatt acatgtgaaa atataagctt gaataaggtt gaagtcaaag
    41941 catatttaga taatgttgaa gtacctttga cagcaggaga atataaactt cttctaagtc
    42001 ttatggaaaa taaaaataga gctatgactc gtacaaagtt actagaaatg ctctgggatg
    42061 tagatggtaa tttcgtaaat gataacactc ttactgttac aataaaacgt cttagagaaa
    42121 aattaaaaaa tccaccttgt ataaaaacat taagaggcat aggatataga atggaggaca
    42181 actagtgaaa actccaagaa atatcaacag tacagttgtt tttataatat tctgcttaat
    42241 tgtaactttt ttattgagtg taattctaac aactataact tcttttaatg aatacaatgt
    42301 actgtctaag gctcttggtg catcatatga gtacaatcct aagtctacag aaagtatact
    42361 aaaatcactg aaaaattcta gtgataagga ttttaaaaca ggaaatgaaa ttttatcaaa
    42421 acatggatat tctaaaagta cactttggag taaaaacttt ttttattttc tagtgatatc
    42481 gtttggtata atttcaacaa tggctacagt tgtatatata atcaaacata gaacaaataa
    42541 gcaaaaactg agtagaataa acaatcttac tcaatactta gaagaagtga atttaggaaa
    42601 agagtctgta cttttacgat gtgaagatga attttctcac cttgaagatg agatatataa
    42661 aacagttggg gaacttcgtt gttcaaaaga atttgcttta aaagaaagac aaactctttc
    42721 agataatctt gcagatattg ctcatcaact taagactcca attacttcta tgtcacttat
    42781 ggcacaatta ctttcagaaa attgtccaga tgaagaaata gattatatta acaggcttac
    42841 aaatcaaatc tcaagacttg agagactagt ttcatcttta cttacattat caaaattgga
    42901 tgcaagtact ttaatatttg aaagcaaact tatagatgta cattctcttc ttacttatgc
    42961 aattgagcct atagaaggtt ctttaagaga aaaacatcag acatttacta tcgaggcttc
    43021 tccttcggta gaatttgaaa tcgatattaa ttggacttta gaagctcttt taaatattct
    43081 taaaaattgt agtgagcata tagaagatgg tggatatata gttgcttatt atagtcaaaa
    43141 tcctctatat gttgagatta tcatagaaga taatggtaag gggtttgctc aggaagaact
    43201 tccatatatt tttaatagat tttatcgtgg taaaaatgct agtaaggaca gtattggtat
    43261 agggcttgct ctatcaaagt ctattataga acgtcaaaat ggtactctac atgcagaaaa
    43321 ttgccataat ggtggtgcaa aattcataat taaattttac acataaaatg ctggattata
    43381 ggtaaaatac ctataatcca gctatatcta tattctatgt tatctattgt tttagtaata
    43441 tacttctatt tacatttaag gttttattaa acaaacaaat taactatccc tatacttgta
    43501 agtagtctta aatcgaaacc tttaaataag ttcaaataga ttttgtttat attgtttcat
    43561 tttttataga ttctactata ttttcattct tcaactgctt gtatcctgtc atatatgatg
    43621 ctattacaat aaaaagtatc aatatagtaa aacctattat tgtagatata ggtgcaaatg
    43681 gtaaatactc tataaaatat atttcattta tacgtagaaa agcatacact attcctattt
    43741 gcacaggaat actaagtagt aatggtgtaa ttcctaagaa taaaccttcc aaaataagca
    43801 tcttttttat gccttctgga gataatccaa cagaacgcaa catagcaaac tcttgtcgtc
    43861 tacttctaat atttcctgac actgtagcaa gtacatttga taatccaatc atagccaata
    43921 aacctgtaat aaagcctact attaaattca tggtctttat tccactagcc ttttgttttt
    43981 cactttctaa aacatcctca atactataat ctcctgaacc atagtcttta ttataaatgg
    44041 actctaattt ttctcttact ctaggaatgt cctcacgatt atttacttta aatactccta
    44101 tcagcctatt tgaacgtaac ctacttactt catcataatt tttagatatt tcctgcacca
    44161 tagacattgg cactatttgc attaatgtat attttgaact agtatctact attttaggaa
    44221 gtgtgcttgt aatagctccc actttcatgt tgtaagtata atccccttta tcttcgtcat
    44281 atactttttc atttaattta atgttatctc ctattgaaag atttaaataa tctatatata
    44341 ctttatttct acgtgtacta cgattaatat cttcctcctt attatataca attgaggttg
    44401 gattttttgt atcataaaat aactttgggt ctacagaaat ttgcctacaa tattctgtaa
    44461 aactcttatc atcaagccca attatatttg aaattatacg aaacttgcca tcacgttcta
    44521 taggagagta ttttttagat gaaactatac ttttaaatcc tccatttttc gcaagttctt
    44581 ttgatgcatc tttttcagtc agccaagtgg aagcagatat tttttgataa tatagtgaac
    44641 tttttacacc ttctgtatta tctaattttt caatgaaagc agactctaca ggttcactat
    44701 tttccaaata aactgctata tctctttggt ccttataatt atcacttcca taaacagctt
    44761 ttgctccttc ttgatttgca attatatgca aaaaacatgt aagtaataaa aaagataatg
    44821 ttaaagatat tgttgcagta cgataagatt ttttacgagc acgtagtgcg tttgatgcaa
    44881 gttctccttc tattccaaat atctttccta atgaatattt atgcgacttt ttgattttaa
    44941 cactatctcc ttgtcgtatt gcttctatag gagatatctt tgatactttt cgtgctggta
    45001 taagtgcaga aatccagact gttactattg taagtaaaac tgctggcaga aaagcaggaa
    45061 taccataagt aaataccact tctggaacat cagtatgata attaactgaa ttaacataaa
    45121 ctataagcct attacacaat aaccatccta aaaataaacc tattggtaat ggtataattg
    45181 tcagtaaaaa tccttcaaac actacagacc ttttaatttg ttttggtgat gcaccaacac
    45241 tagataatat ccctaactga gtaagtctag catttgcaga cagtgaaaac gcgttgtaaa
    45301 tcaccattac aaacacggct actgtaaaaa ttgctattgt aagatacata ataggagttg
    45361 aaaattttga tatactactc atagatgctt tctgttctgg tgaaaagact aacatcttta
    45421 aaagataatt actattgtat ttaagattgt attttccata ttcattagtc ttccacccca
    45481 atgatttagc aagttttgga agttccttat acgtgtctct tatattttta aatcgcaagt
    45541 acacagttat actatcatta ggttttatac ttgttttatc aagatatcca agagctgtat
    45601 atgcaggtat tactgatgaa gtagaaacat ctacctttcc tactattgtc aatgtagtct
    45661 ctgaaatttt tttaaaactt tcccctttcg attttggggc tatgggttca agaggctttc
    45721 catttaggat tctatctcct attgggagag taattttatc accaattttt acacttggat
    45781 tattctcaaa atattgtttt gataatgcaa tttcattagc attatttggt cgacgaccct
    45841 ctattatagt atccttttct ggcatagaat cccaatactc tgatgtagca tttctataaa
    45901 ttatataatc tcttttctca tcattaattt tgcctacata ccattgtcct tttaccatta
    45961 catcatcaac tgaagaaaaa ttttcaatta atggtaagtc acttccataa gtatagtcaa
    46021 acaattcacc atgccagtta ccttctttct caattgaaag tcttataaaa tctgtccaca
    46081 tggtatacaa cagtccacac aaagaagaca tcatggttgt agtaagtaat atagctaaca
    46141 ttatagctat actactacgt ttattgcgtc gtacaaagtc taaggtgtat tcttgaagaa
    46201 tattcatttc ttcaccacct tttcagagac aatcactcca tcttccatag ttacaatacg
    46261 atttgcctct agtgctattt tctcatcatg agtaataaga agtattgtct gattaaatcg
    46321 tttatttgat aagtttaaca aatctacaat ttcttctgaa ttttttctat cgagattacc
    46381 agttggctca tctgctaata aaatagctgg tctataaatt aaacttctag ctatagatac
    46441 cctttgttgt tgtccacctg aaagttgact tggaagatgg tttaatctat cagataatcc
    46501 caatatagat acaatctcag agaatctatc ctcatccacc tttcttttat caagtaacat
    46561 gggtaataat atattttttc taacatcaag agtaggtata agattataaa attgataaat
    46621 aagacctact tttctacgtc taaaaactgc aagagcttct tcctttaaac ttgatatttc
    46681 tgtatcttca acataaatct ttccatatgt aggtctatct actcccccaa gcagatgtag
    46741 caatgtagat ttgccagaac cagatgctcc tacaatggat acaaaatcac ctttttgaac
    46801 tgataaattt acattattaa gggctgtcac tctggtttga tttgaaccat atatttttgt
    46861 gagattttca cattttaata tttccatata caatcatctc ctttatggtt aaattttagc
    46921 aacctaaaat gacattatag tgacatgaat acaaatataa attactatta aaaatattgt
    46981 ttagtttttg cacattattt aaaattataa tataaaacaa aaactatgca atatatttta
    47041 tttatacttt taatatatta catagtcttt aaaaggtatt aactttaaat ctataggtat
    47101 tcaatttaat aatcaatagc aagtatttta tgtactaaag gagttttgct ctatatagac
    47161 tcaatttagt aaaattattt aataaatatt acagactata ggtaaataat atttacaaat
    47221 aaaattaagt ttattccctt acactataat atttcttaat tatattaatt gcaatttcct
    47281 ttacctttgg ccctgtaatt tctttattgg aatcatctga tttaatagca aaataatagg
    47341 tgtcaccttc acgctctagc ataccaacaa accatgcatc cacacattta tttttttcat
    47401 caaatcctgt tccagttttt ccatatacat ttatgttttt atcatttaca tctattttca
    47461 taatatctct taaaatatta atatgctctt ttttaaagtt tgtatctccc tcaaatattt
    47521 ttgccattgt ttgcacttgt tcttttggag atatttgtaa tgaagattct aaccaaaatc
    47581 catttaaatg tccctttcca ttttttaaat ctccttccca ttcgctaata tcgcaattcc
    47641 catactttaa atcatctaaa atgttttgga cagatttagc atcaacttta tctatcaatt
    47701 ttttgtagta ccaaacacaa gactccttaa atgcctcttc taaactaaga tttttattcc
    47761 aatttttatt tggatactct gtaccatcat atcccataac tgattctttt gagtttatta
    47821 cccctttttc taaaccaatt aaagttgaaa ctattttaaa agtagaacat ggtgaccttc
    47881 ttgtttcaat taattctttg ttatatatat tatattcttt atttttagta ttataaaaaa
    47941 tagctcctcc actaatacct tcaaaacaat cactatagtc aaccatatta attttttctt
    48001 ttttgttttt attattgttt tcaattttgg atttatttaa ttcagactta tttaattcag
    48061 attttatata attcttatca gttttttgat ttatatcgtt atgttttttc cctacataat
    48121 acattaccat aactacacca accaataaga tagctatcca aataaaattc ttttttcttt
    48181 tcataattta tatcatctcc catatttaaa tttataacct actattaaaa tagtagacat
    48241 tatttgtaat atactccaat ctaggttcta cttataagaa acaagactaa atgaatagct
    48301 gtatctctta tattttcttc acctagtaca attatgttga ttaaacctat tgcgaagata
    48361 attaagtaac tattaataac atcctgtcct ccttttaatt tgtgatataa taattgattc
    48421 cacatttaaa acttactatt gtaatattta aatattacaa tagtaagttt taaatgtcaa
    48481 gttagtttgg gaaagttatt ttaattgtat aattgttatt acatttataa aatatggcat
    48541 gtttaaaatt attttgctat tgggaggatt aagataagca gtattataaa agctataaat
    48601 tataaaattt aatatataat ttatagcttt tacttttaca aatattgttt ttattgattt
    48661 attaatgaat tttattgaca ggttatattt atataagtaa acacttacat aattaagtat
    48721 ataatctaca tatctataag ttgagtcaat tcacaagtat atgtcaactt aagtttatgc
    48781 atagctcgtg tacaggcaat atataacaaa ctgcggtcat aatcactata atatgtttta
    48841 ttatttactg aaggtacaat aacttcatca aactctaaac cttttgacat tttaatagaa
    48901 gttatggata ctccttttgt aaagctagaa ctttcagaag atattaagtg aacactatat
    48961 tcttctctta acgcatcata tacagcttta gcgtcattat ctgtctttaa tataatacca
    49021 agagtcgcat tatcactctt tttaaattct tcaatttcta tttttatctt atttatttca
    49081 tcttgctcgt tattacattt taataaagct ggttcttcac catgtcgttc aataggctct
    49141 aatgaagata tgtcttgaat ctttttggcg aaattaataa tctcaaaagt agaacggtaa
    49201 ctcttgttca acataactaa ttccccatca ttatatagct gtttcatatc atctaatgta
    49261 tgagtatgat taggattaac caattgtcca aaatctccaa gaatagtctt tttacactta
    49321 aaaagtaagt ttattacagc atattgaata ggtgtataat cctgcatttc atcaataaca
    49381 atatgcctta taatcttatc ttcttgtata ccttcatatg tagcatgaat atatataaat
    49441 gggtatacat ctgaccattc aagtgttttc ttttctacca tcacaaacat gtttgatata
    49501 ttcatttgtt taaagaaatc cttatatagt gtaagagtat tttttattgt caacattcca
    49561 ttcaaacttt taagtatact ttttaccttt ggtaaatctt cttccataat attatctgat
    49621 tcaaatttat aatgaatgtc ttcagctacc ttctctaatc tcttcttaac tggatatcta
    49681 ttatatgcct caaatctact ctgtatccag tcacttttag ctgtaaaact tccaaaagtg
    49741 tagtcttttg gaataaaaat cttatttggc atttgtttta tataatcatc aataagtttt
    49801 acaaaatcaa gtgtagattt aaaacgcact ctttcagacc atttagcatc atttatttct
    49861 aatgggtctt tctcactttc aaaattaata actctatcta attgtacctc tgctatattt
    49921 tcaaaactta attcacataa tggctcttct ccaagctcag gaaggacatt ggaaatatag
    49981 tctccaaaga ctttattagg tgataggata attacattat ttgctgatat tttatcttta
    50041 aatcgataaa gaagaaaagc aattctgtgt aatgctatag atgttttccc agaaccagct
    50101 accccttgaa taatcagtgt atcagcttta tcatttctaa taatttgatt ttgttccttt
    50161 tgtattgttg aaatgattga cttcattttt tcatctgaag tgtgactaag ttctttttga
    50221 agaatatcat cttgtatatt aatggaactt tctagtgcat attctaattt tccattttta
    50281 attttaaatt gtcgttttct tgttatttct ccatccaccc atcctattgg agcatcatat
    50341 ccagcttttc cgatttcata atcataaaac atactggcaa ttggagaacg ccagtcaagt
    50401 attataagct catcttcata atcaaatgca aatctaccaa tataatactt agattcatca
    50461 tccatatctt tcagcctaaa atctattcta gcaaagtatg gagaatcttt gattttatta
    50521 atcttatctc gaacttttac cataaaagcc ccatagttat ctatttgttt tagtccttgt
    50581 tcattttgaa acatttcatg tgggtctatt tcaccacgat tttttaccat atacatttta
    50641 gcgtccatat aatccttatc aagcttgtca acaagatttt cagctttctt aaaagcattg
    50701 tctagcttgt tatttatctc tattagatgt gcaatctcat ctggaaaaaa agttaataac
    50761 tctgcatcat attcacacat attatgttta gaattagatg caataatatc gcaatttact
    50821 acttgtttat tttcagacat ttaaatcctc ctttgttaat taagtactta cactgaatca
    50881 ttatacttaa ttgtgttttg gagtttttaa tcattcttgc tatttaactt aaatgttagc
    50941 tttttagctt taaagttcct tttttaaaaa actaaatctt tctatattta ttaccataag
    51001 tacacttaca agcaaaatac attaaaagca gaaatgctct tatatataaa ataattcaaa
    51061 caaaaaatat gtggtaaact tttcatttaa tctacaatta attttgtcta ttatctcttt
    51121 cttctacaca aggaagaata aatttttgag taggatatcc aaattccaca agcaattctg
    51181 cttctgcaaa gcccaacttc tttatcatat ctctatgtcc tgtatcagct ttgtcaccct
    51241 ctcgaaaggt agtaattgaa atatctgtat ctatcaagaa atcttcaata actttcttca
    51301 aaaacacttg tgcaatgtct gaattacgat actgtggatg tattccaaaa aaatcaatac
    51361 ttctagtttc tctattaaac accatatttg caatagcgac attattaagt tttaatatta
    51421 aagctctttc ttctaaaata tactgttcta attgatatat atattcttcc tcttgcaaat
    51481 ttggaaatcc atctatgact aatctcacta aattcatcca taatggtatg tcagacatac
    51541 ttgcaagttt aatttctttt tccaactcta gtacattctt tgaaaatagg ttatcttttt
    51601 tcaaaacaaa tcttagctgc aaaggataaa attcttgttc tttcctatat ttatttggag
    51661 attttttata catagcttta aatatagaag tgaatgcctg ttgactttca tatccagcta
    51721 tcaatgcaat ttcaataatt ggtttctttg aaaataccaa taattttgct gcttctgtca
    51781 actttctccg ctttatgtaa tcatgcattg ttagaccaac agaagttgtg aaagttctat
    51841 gcaggtgata ttttgagtaa tgaacagcat tagcaactat atctaaatcc agcttttctg
    51901 ataaatgctc ctctatatag tcaatagcag ttatgacatt aattactttg taagacattg
    51961 cagcttccct ccttttatcc atgcaacatt atattaatta taacttagtt atatttaatg
    52021 aatcttaggt cagtttacaa ggaactacac gcagaccacg aaacggggct gcttacaaca
    52081 aataaaagct aaacatcaag cacagggaaa gcgcgaggtg ttcagactgt tttgttgtct
    52141 ggaatttcca aaggggcttt ccccttggca aacgacttta cttgcaaagt gtagtgtgtt
    52201 atacgctctg ttggcgttgc cgtaaaaatg ccgttgccgt cagggaaggc aagggcattt
    52261 gaagcggcag gaaaacagga ctgtgattgc atagcgtgaa gccacaagcg cagggcgggt
    52321 ttcagcagca tacatgtgta tatgaaagct cccgtccctc atcctacgct ccaacttgta
    52381 gccacactca cgaaaaagca gacggatttt cctctcaaaa ttgaaatagg cgggaagcca
    52441 ttttagggct ttcccatctt gattgcccgt cagcaaaatc agacggtgct gtcaacggtg
    52501 gcacatgaaa tgcgccgttc atcttgacca ttgactggct tggctgactt tgctattttc
    52561 tatgattgtt agttgcttga tacagatagt tgccttatca aatccaatgg tgtggtaaaa
    52621 gatattacag cgcttactct atcgccagaa ccccatttta ccagtccaaa atcaacattt
    52681 gcacgatagg cacattgcat atatactatc cccaatataa agcagttcat tgttttgaca
    52741 ttttgtcagt tccatgtatt tcaataatgg tactgctttt ggcttatgct ctagagtgtc
    52801 attggagcat actacagtat taaagtatgg tgctatgtca aagctcagaa aatcgtttct
    52861 aaattcttca tgagttttgg atgtaacaat tccaatgcca atatttaatt ttatgagttc
    52921 agtaagcatt tcctttattt ctttgaacac aagaactgta ttcttatact tttccatatt
    52981 cctatcccac attgatagag caattgttat atcttcgatt ttcaaataac gtaaagcgtc
    53041 ctcgcctgtt attcctaaag caaaagacaa ttctttgata ggaattatct ttctattgat
    53101 ttgttttatc gtgtcttgta gagagtgtaa aatggcgtat tcagtatcaa tcaatgtgcc
    53161 gtctacatca aagacgattt ctttgtaatc cattaatttc tccttaatta acctaatcga
    53221 aaatcactgt ccaagtgtct gtacgacatg cttcaaagca cattttaatc tgttcttctg
    53281 tatttttttc tgtggcgagt tcaggaagtt cattttcgga gaaataagaa aactccgtag
    53341 tttctatatt ttctttgaat gtacccccga taacggtaca aagaacaaat attttgcata
    53401 ctccgtaagc atatataggt aaattgtgtt tcgcacggtc ttgaattgca ataatcctgt
    53461 cggcggttat atctaatcca gcttcttctt tgacctcttt aatagtattt tccttgactg
    53521 ataaatttac ttcaacccaa ccacccggaa gcgaccactt ccctgtattt tctttaacaa
    53581 gaagtatttt tccattttca aaaataacgg ctctggtatc aagttttgga gtttggtatc
    53641 cgctttcatt gcaaaaaaga tttcttactt tttctgttga tatgtcagtt ttatatgcta
    53701 tcatttcggc ggaaatttct cgtattctct catatcgctc tatgtcgtat atatctttcc
    53761 cataagttat tccggcttga gcaatgcttt gcaattctat cgcccattcc aaccattttt
    53821 cgttcataaa attacctcca gttttccgaa gaatatatta taattagtta cttagtagta
    53881 aaatatattt ttaactaatc ctgctttgta tgttgaacat attctataat tgtaccatct
    53941 ggatgtctca atgtcatatt atatcctgta ggaacttttt tcttatctct tactacaact
    54001 gctccattat ccaatagata acttctccat tcatcaacag aatcaaccat aaaagtagat
    54061 tttgtttcta taaatggttt aagagcatca tcagaaccag ataatagtaa aacatttcct
    54121 atttgcgcta attctaaccc aacttcttta taagaaaaac gcaaagaaca tttttctttt
    54181 aaaagattct cataaaaagg tatggctttt tctatatctt gaatataaaa acgtgttaat
    54241 atatcatata ttttcatatt ttccccctat atatctatat agtatcactt ctaaattata
    54301 ccactctaca aattatataa caataaatta agcatagcct tttgagcatc ttaagtagac
    54361 cttaacaata tattggggtt acattagaat aataaattaa atctaaatta cactaagtta
    54421 gttataaatt gattatctac agttacatta gaatacataa attaaatcac cttgatatta
    54481 tttaggataa aatttatgta gtagcagtaa atgttcttct aattatcaac taacaaacga
    54541 taatctttaa ctttctatat aatgggtaac atcattttcg taagatattc actagctgga
    54601 cgattgatat catttaaata ctggtaatat atatcgccat gaagtttata tccattgcta
    54661 tttgcccatg aaaataagtc ttctaaagta gggtcttgta attcataagg tcctaaatca
    54721 attgcagtta ttattttctg tgcaggaaca atcctttgta gaatctcatt tttcccatct
    54781 atataagtgg ctacaggaaa ccctacttca acatccaatt ttgctaaatc catgttatga
    54841 aaacatacaa tcggtgctcc tgaagataaa attcctctct cctccagata tttagaaatt
    54901 ttttcaaaac tttgttttga aaactctgaa aactctacca taaagtcaat tgtttttcgt
    54961 attgccaaaa aacagtactc agattgttca gctattgtta tattggatat tctagtcatt
    55021 ttattcctcc attactttat tttcatttct aatcttttta taccaaatta tacgaaaatt
    55081 cactgtgtaa ctaattattt catatgaata taaaacataa cctccttcca tttcttatat
    55141 cgaaagtata gcaaaaacaa tctcatcatt cttgtcacac agtgctctta taatcagaac
    55201 atacttaaaa gacttgccta atttttaggc aagtctaaaa gaaatctttt tctataaaaa
    55261 atttatacaa acaattaaaa tatcaaacat caaaatttaa acaagtttca ggttcatctt
    55321 ctattcttgc tattttaaac ttacatgcaa ttaatactaa agatactatt ggatttataa
    55381 tatttaataa agcgtatgga ccatatgtta gtgcagatac acctaatgtt gctgttatat
    55441 acgccccgca tgtattccat ggtactaatg gagaagttaa agttccacta tcttctaaag
    55501 ctctcgacaa catcttagga tgtatacctc tctttttata ttccttatta tacattcttc
    55561 ctggtataac tatagataga tattgttcac ctgctattat attggtaatt gtacaagtta
    55621 ccatagtaca taatactgtt ccaaatacac cctttgctaa tcttagtaaa gaagacgcta
    55681 ctacttcaag catacctgtt ttttctaaaa tacctccaag agataaagcg catattgtta
    55741 aggatacagt ggacatcata ttcataatcc cacctttaga taataaagca tctacctctt
    55801 gtatttgtgt tgacgaaaca tatccatttt gtgctgcatc taatatcgta ttcatagatt
    55861 ctccttgaaa aactactgca aacaatactc ccaatacagc acctactata agccctggta
    55921 tagcaggaac tttaaataca actaatccaa ttactattgc tggagctaat aataatactg
    55981 gtgataaagt attaaatgta gaatctaatg tagacctaat taattctatt tgttttatat
    56041 ctagtgcttg acctgaatac ttcattccaa ttacaccata aattactaaa caaattaata
    56101 atgatggtat agtcgaatat agcatatatt ttatatgtgt aaacaaatct gttcctgcca
    56161 ttgctggagc taagttagtc gtttcagata aaggtgatag tttatctcca aagtaagctc
    56221 cagatattat agaacctacg attaatccaa ttggcatacc taaactttga ccaatgccta
    56281 aaagagctac tcctactgta cccattgtgc tccaagatga acctgtcgca agagatacta
    56341 ttgcacagac taatgttgat gctactaaaa aaatatttgg tgataaaatt tttagtcccc
    56401 agtaaatcat acatggaact actccactta ctatccaagt tcctataagt acgcctatta
    56461 taattatgat taagattgct tgcattgcca tctttatact attaaacata cttaattcta
    56521 actctttcca tttaaatcca agtctatata cagccacaag tcctgctact gctgctgctc
    56581 ctattagtgg tacatgaggt gatgaaccat acactaatac tcctagactt aaaaataata
    56641 tcaaacaagt aattggtatc attgcatcaa acagacttgc ttttctacat tctcgctctt
    56701 tcataaaata gtttcctcct aattatttaa acactacact ataatttttt ttgaaacata
    56761 tttgctcgta ctagatgaca tgataccccc ataagttaat aaaaattcta aattgtcacc
    56821 taatttataa tcatattttg tgttacttac atctagtatc atgtggtctg aacttgcccc
    56881 taatattttt atatcagtgt ctattggaat taaagagtca atatttatat cttgtttacc
    56941 tatagctatg attgcccttt ttaagattcc cttatcttca taaacaggtt tatttctaaa
    57001 ggcatcaact cctatttctc caataggaac tgatggtttt tctttacatt caactacttg
    57061 gcatattaat ttaaatgcat cttgatatgt tccatttata ttttcaccgt atgccgtttc
    57121 tctaccaagt agaatggact cgcctattct caaattagta ataccttctg gcatattatt
    57181 atttatcaac agatgaatcg aacttgaatt acctccagat actatttcta gatttattcc
    57241 aaatttttct tccattcttt ttgctatact taccagtctg cctatatttt ccctagatgg
    57301 tataatagct ccataacagg ttaagtttgt agctatacca attatttcaa tattttttaa
    57361 tcttactatc tctcttacat tattaaaaaa gtcttcttca taaaagtatc cttctcgtaa
    57421 atcgcctaag tcaaacataa gaactatctt atgaataata tttttacttt cacataattc
    57481 atttaatttc tttattgttc ctaattctga gttaaaacta atatcgcaat aattgataac
    57541 ttcttctaat tcacttaaca ttgggattct aatcaatatc ttaggtagat ttatatcttg
    57601 taaatttttt aagttttgta ttcttgaatc tgctatatgg tctattcctt cactacatat
    57661 ttcttctact atttcttttt gtgcacaaaa tgatttagta acaaaagata tcttaatatt
    57721 tctttcatga cacatctgcg aaattaattt tgcattatgc tttaactttt ctatatctat
    57781 ttctaaccta ggatacataa tctttcctcc tcaaaattca aactttttaa caggagctta
    57841 agagatgctt cttcatattt tttagataaa acacccatag atgccataat atagtcatta
    57901 tctattaata tctttgtttt ttcctttgga aatagtaatt cattattttt attgtatttg
    57961 agcatattat ctaatatttc aattctacta gggagcctag taagtgctcc ccctgtacca
    58021 actatatatc ttacttctgt taaatctttc ccttctgcaa ttttgacttt tccagttgtt
    58081 ccatagatat ttcttatttt tcctgaatgt cttagcatag ctttaacaac agcttctttt
    58141 gtcaacctct caacaaataa tatttcttct tttgattttg gtattggagg ataattctct
    58201 attactgcat caatatctat agatagttca ctttgtaagt tttctttacc tataacttct
    58261 actatattct tcatatttac atatacacct aaatccccct caacacttct ctttgcagta
    58321 ggttcaggat taaccaaaat tttattaata tagtcacttc catctgtaac agaatgtaca
    58381 tcagtagttg ctccacctac atccagagtt aataaatctc caatattttt atataaaagt
    58441 ttagaagctt ccattacagc tcctggggtt ggagtaatat tttcattaac catttcttta
    58501 atgtatttca ttcctggtgc tgtagttatg tgttcttcaa atacactttg aatgattctt
    58561 cttgtaggtt ctatattcaa taaatctatt ttagggtata cattttcagt tatataaagc
    58621 ttataattag tatcttcaaa tattaacctt atttcctctt gattttcaac attaccagca
    58681 tatataactg gtatgcctag attcatagaa gctatcattt ctgcattata aatagctgta
    58741 tctctttctc cataatcgac tccaccagct attaaaatta tgtttgggtt tatttctttt
    58801 attttattta aatcagttct tttaattcta cctgatgtta tttgacgaat aacagctcca
    58861 gcccctaaag ctgcttcttt agctgctttt actgtcatat catagactaa tccatgaaca
    58921 gtcattttta atccaccagc tgcactagaa gttgcaaaca tatcattata ctctatatca
    58981 tctacagata atttattagc taaatcttta atagcacctg ataagccatt tcttacatcg
    59041 ccaccttcaa acactgttgt tggagcttga ccttgaccca aaaatatagg attgttagta
    59101 ttaatatcgt ggaaagcgtt taccactgta gtagtacttc caatttcagc taccaacaca
    59161 tctattttta aagaaacttt gctattttcc attatttatt actcatttct cttctttttt
    59221 caactaagaa agtggctaca tgtatgcctt tgctgtttct tccaaatcca gcatctatgc
    59281 cttgttcaac agctatttca ggtgttactt gtgttcctcc acacgcaatc attactttat
    59341 ctcttatacc tttttctaca caataatcgt gtaatttttt catgttttta tagtgaatat
    59401 catcatgact tattattgta gatgcaagta ttgcatctgc attcagttca atcgctgcat
    59461 ctaccaattt ttctacaggt acagaagtcc ctagatagtg gcattctatg ccatattttt
    59521 caatacctcc atgttttata tctattattt ctcttaaacc aactgaatgt tcatcttctc
    59581 caaccgtagc tgaaactatt ttcataggtt tttcttctat atctgctctt atttcttcat
    59641 cagttagtac cttaggttct tctggtatta ctaaattgtt taaatctata tcaaacggaa
    59701 ctcttccttt cacttctatt ctagtccctt cagattcatg cataacttct ctacttatga
    59761 cctcaatttc ttgtaagttc atttttttga caaattccaa agctgcaaac tctgctgttc
    59821 ttttatcagt aggaagcatc attgttatca ttacaattcc atctgcacac cattccattt
    59881 caggcttaat tttagttcca tttctgtact catatgattc ttttagtcta ttttctacat
    59941 tatcaaaatc gtcaagctca tcaatatata ttattttgtc tggattttca aatgtacatc
    60001 catctattaa cattgatgga ttatctatag cattttcatc atattgagct acattattgt
    60061 atccaaagtg agcagttaca ggtgctaaat aatcttcttc tctttcataa acagtacctt
    60121 caccaactcc accttttatt tttctagata ttccatcacc atttctttct ggataatttc
    60181 cagaatcaac aaaaaatcct tgttccacag attcaaaata tccaccaact tcagatattt
    60241 cttccatata taatacagct ctttctttaa gttctcttgc tttgtctctt aattcaccga
    60301 catctttaag ttctatcata tccataagcc catccatacc aactaaagct tgctttgctg
    60361 tatcacatgc ttctatattg tatatatgcc aaggtacatt tctaccttca tcaggtgtta
    60421 tagttgattg tatgtcagct ctagttaata ctgatgttaa taagtttaat acatgagtaa
    60481 ctgttgcttc tctagttgat gattccatat atttagtatt catttgagct ctcatcttat
    60541 aatcactaaa taactctcta agtgcaacag cgtaaggtaa gtctattttt aaacatggtg
    60601 ctggaggtgc tgttggtgga actgttgata agcatatatt acttttatct atacctattt
    60661 tttctgagaa tatagagttt aaagcgtgtt gaaccataag ttcaggcatt accttccatg
    60721 cttctctagc agtagcatta gcattatgtg ctccatcaat ttgagctata ttggcaaaag
    60781 ccattatttt ctttgcctca caagcatcta caaaagacct taccatgttt atattcctat
    60841 acagaacatt atattgtggg tcttgatgtg ctccattgac tccttcctca gcaaacatta
    60901 ctgctacttc aggaccagca acaccactta catatgaatg gtaattaata ggtctaccaa
    60961 cttcttcttc tataaaatca agagccttcc tttgagctct tacttgtttt cttgttattg
    61021 gaactccacc tataccttgt ggagttcctt ctataagccc atcaaaatgt gattgtccag
    61081 cagttctgat aaccattaga tggtcagctc catgatgagc tgccattctc attcttctta
    61141 tatcatcctc aaatctacca gaagctattt cagtagtaat aactggactt ggttgagggt
    61201 ctatattatt gaaatactta gatgatggta gccctacact cttctttaaa ggttttgtac
    61261 agtctttata tttaaaaggt cccatttcaa gattttccaa gtgttctctc caaacccaac
    61321 ctcttcgttt tggtttatat ttatccaaat cttttaatat atagtctata tccaattttt
    61381 tattttcctt taacatgatt ctaccccttc tctaaataaa catgtaactt catcccaata
    61441 ttcaccctta actaataaca aacctgcttc tctaaccgtt atatttttag atttagccaa
    61501 tttataaact acatgccctg ctcctttacc tataagacct ctttccataa ccccttctaa
    61561 aataggtttt acttcaagag aagaaaatcc cattctcaac aagacagacc tttctattga
    61621 tggtgttgta ttctttttac caagttctat cattggttct actatctggg tagctaaact
    61681 ccaaaacctt tcttttaact catcctcact cagttcttga agatgttttc ttctaacttc
    61741 aaaatcatcc tctctttttt tcatgaacat tcctccattc gtattgattt aatcgaattt
    61801 tctgaatttt tattttatat taaattaaaa aacaataatt actataaatt atttaataca
    61861 tcaacaacaa aatctcttga actttttact tcttccatta aaaattctat atctcgatta
    61921 cttagcttat caatattatc aatgtgatta ttagatatac aattttttat aaatgacttt
    61981 cttattttat tcatatcaat atcaacacat ttcaataatt ctggtctttc tggtaatatt
    62041 aagtttactc ctgcaatttc ttctcttgga tttccaaatt ttatatctat tccattttct
    62101 cttgcaaagg taagttgtgg acatatatgt ttacctgcac ccgtatattc tgtttcttgt
    62161 accactatag ctttatcctc atctagctct tgagctaaag agaatgctgc tgctaaagat
    62221 gtatttcctg ctggacctct ttctatacct tctagctgtg ccaataattc agttgtataa
    62281 aaaacttctc cttgttttac taatacatat ctatccatat atctaagtgg tctagctgca
    62341 gacctaggta catctgacct atcaggccat gtacagtatg gtatcccaaa acctgtatgt
    62401 cctgttgtaa atgatttttt attaaattga ttatcactag ccatgtgtaa tccttttaaa
    62461 tctacacttg ctcctactac tttagtatta atagaaccag cttttatcaa tcctcttgca
    62521 gttccagtaa gattaccacc acctgcattt gtacaaacaa ctatatcagg gtctttttta
    62581 tacttttctc taaattggat agctaactca taacctaaag tttctacacc tgcaattcca
    62641 aatggtgaat ataatgatgc gttaaaatag cctgtttctt ctaataaaac taagaacgta
    62701 taaaataact ctggtccaac agttaactga acaacttctg ctccatatgc ctcacatttt
    62761 cgcgcttttt ctatgatttc aggttgacct acaccattag aatcataaca ttcttgaact
    62821 attatacatt ttaatccctg cattgccgct tgtgatgcta cagctgcacc ataattacca
    62881 ctagtagctg ctattacacc tttatatccc atttgtttgg catgatatac tgcagtagct
    62941 gctcttcttg ctttaaaact accagatgca ttcattgctt catcttttac aaatattcta
    63001 gctcctttac cttctttagc acattttcta gctaatttag tcaaattttt aagctctatt
    63061 aaaggagtat ttccaacagc atactgtgat tgaattgctt caatatcttg taatgtatat
    63121 cctgtttcac tcatcatttt ctcataatca aaccctattc cctcttgttc aaaagaagaa
    63181 taatccaatc cgattgcatt tttcattatt tcgttatttc ttcccataac agcttgataa
    63241 ctcatatctt tcattgatgt tgaattattc attatataca cctccaaata atatttcttt
    63301 agcttggatt cctatttgga gtaactctgg tatacattta ccataatcat gagtataata
    63361 tggatttact ttaagtaaat taccttttac aagtctacct gtaattgttt taacttctac
    63421 taagtcgcct atagaagcat cactttgtat aaaaccttta acccacattt ctaaggatac
    63481 tttcttagta tcctctggaa cttgtggagc tctttcttct ggagtcaata ctatattgtg
    63541 tataataacc caatcattaa ttttagcatc cattttttca tccccttatt aattgactat
    63601 tgccttacta attaatttac tgttatttta aattaaacat tattttacca attagctaac
    63661 tgttatctta ctaattagct agttgctatc ttactaatta gttagctgtt atcttactaa
    63721 ttagcctttg attcttcttc caattcaact tctatctgat ttcttatatc tcccattatt
    63781 gctctaggta ctggtatatc caacatagtt ttaagacctg gtctagcatt tattattaat
    63841 ggaatagagt ttactatcat tgcataagta cctactcctc caggtatttc aggatttatt
    63901 tgtaaatcaa tgtttggtat accttttatt gatacatagt ctcctgtttt aataccttct
    63961 gcttctggta ttatctgttg tggatgctcc atttcaatta aaacttctcc atttacatat
    64021 ccatatccac attgtctaca accagcaaca tttccagcca atgcctctcc gtacttagat
    64081 tttctatcta ctgtagtcat tattggctct tttgtttgtt ctatcttatc taatttccaa
    64141 cctaatccat cagctatcat atttattgat tctacaaaac ctacatgacc tgctatagtc
    64201 ttatcttcta caccttttat aaattcttcc cttgttactc caacaccttg ttccaccata
    64261 acagactttc caaatggaga taaatcattt actctcttag cttttatact agtaacttct
    64321 tcacaagtac ctgaaagtgc caatactagt aaatctaata caaatcctgg atttattcct
    64381 gttccaagta tacttactcc attttccttt gcaacttcat ccattttttt agctaaatct
    64441 gcatcatcag cttgtggata tgccatttgt tctgctgttg atataacatt tatttttcta
    64501 tttaataaga aaattatttt atcaaaagcc tttttagtaa atgaatcagt tgctaacaaa
    64561 acaacatcta cacttttttc tctaaaaact tcttcataat ttttattgat aataacttct
    64621 ggtctttctc ctctttcaat tcctaaaaca tcatacatac ttttccctga agtacttcta
    64681 ctacaaacag atactatttc tataccttct ttctttagaa tcatattagc catacctatt
    64741 cccatagctc caaatcccca tattcctact cttacttttc tcatatatac accctcctaa
    64801 aaatttatat attctcaata attagttaaa gcataaatcg tgccaacttt aaaattaaag
    64861 taaatattta ttggaacgtt gaaactataa ttattttatt atgtattttc ataaataaaa
    64921 aataatattt cttatgagaa ataaaaaaaa gagcaaaata ttttgctctt ttataataat
    64981 tttgctcctc tattttgctt ttttatttta ctttgatttt gtttttttat cttgcttatt
    65041 tataatattt tgatattata tttttttatt ttatactgta aattttgcct attcatacct
    65101 aaaattgatg cagctttagt tatattgtaa gatgcctttt ctaatgattc atatatatac
    65161 ttttcttcta tctcactgat aatcttacta agtgttttgt cctccaaatc gtttaaagaa
    65221 taattgttac tctctttatt ctctttaaga ttgtaatagt cgtttagatt aatcatactt
    65281 gtttctattt gtacctcatc ttccatcata ctcatagtac aataaattat gttttctagc
    65341 tctcttatgt taccttgcca atcgtaattt tttaaaattt taatagcttc atctgaaatt
    65401 cctaccactt ttttatttaa ctttttatta tactttgaaa taaatttttt gcacaataga
    65461 ggtatgtcct cttttctatc tctaagagga ggaattttta tatgaattat gttaagccta
    65521 taatataaat cttttcgcat tttatgctcg tttaaaatta cctttggact ttcatttgtc
    65581 gttgcaataa ttcttacatc tataggtata tccttagttc ctccaaccct tcttacataa
    65641 ccttcttgta aaacccttaa tagtttagcc tgtaacataa taggcatgga atttatctca
    65701 tccaataaca atgtcccttt gttagcttgt tcaaataagc ctggcctatc tattgctcct
    65761 gtaaatcctc ccttgctagt tccaaaaaga ataccttcga atagtgattc cggcaaagct
    65821 gcacaatttt gtgctataaa tggatagttt ttcctattac ttccatagtg aatggactgg
    65881 ctaaataact ctttacccgt tccagtttca ccgtatataa atactgaagc atcagacttg
    65941 caagctttct tagatttagc tattgcttct ttaatcaaat tactttcccc taaaatatca
    66001 tcaaattcat aacccttttt ttgtctacta ctaactttat tgactaaatt ttttttataa
    66061 tttctgttta gtaaattttc tatcgttgtc atattctttg atatttcaag tgcccctaca
    66121 aactcgcctt taatatcaat tggtattgta gtattaattg ctgttatctc ttttccattt
    66181 ttatccagat atttttgaat attgtctttg ataacttccc ttttttccaa aacttctaat
    66241 agtgtactcc tgtttatttt cattttgttg actatatcaa aaaatgaatt ggttaaaata
    66301 tcatgtctgt tcattttttc cattttttgt acagaattat tgtagattat agttttcccg
    66361 tctttattaa caaaatgtac cccttcatca atattttcca atatttcatt cattatttta
    66421 aaaaatatct cttggttcaa ctatatcacc ccagtaccta aatatataaa aacccaaaaa
    66481 attaataaaa tgttgctatt gtatttatct tatcatatat tgatgatatt ttttatgtac
    66541 attatattaa tatattttta agtatattta aaattttatt tatatatctt tcattatggt
    66601 tatatacaat atttgaattg tcattaaata taccaatagt tttatatatt attgatttta
    66661 ttaaaaaaag agatatacaa actaataagt tgtaatctct tttaaactct aaattagaat
    66721 tactctaata tataacttac aatataatcc aatgtcctgt ttatagtaaa aaccacattt
    66781 aaattttaga ttggatgaaa attattaaga ttatttataa actcaaattg ttactctcct
    66841 ttttcttatt atcttttgaa tgtattcttt agttaaaaag ttttactttc tcatatatta
    66901 taaaggaaga taatttttta caaataatcc acttaatagc atccttactt taaacctaaa
    66961 gttcctctat tccaatttct tttaagtatt catacacacc attataaaaa tttggctgca
    67021 ttgtaatatc actctcatca cctattggga caaatataat aaagccttgc cttgcccttg
    67081 taagaagaac tctatatgca ttttttaagt atagtatatt atcttcttta ttgatgttct
    67141 gccatttagt tccattgaag ttatagtatt caaaatggtt attcttaaat cttaagttcc
    67201 catcccaaca gacaattgtc cagtctagct ctaaaccttg gatatcaaac tctgttgcag
    67261 tttcttctaa aaaatatgaa gctcgtacat catccttacc attaagaaac cagtttgtag
    67321 catcaatttt attttgtacc cacactccat actttcgaag ccgtttagct ccagaacttg
    67381 cagtcattcc ataacgctgt gaaccttttg atttatctct cacccacttt ttagctaatt
    67441 ccaaatccct agtaacacat atagggtaat cttttttaaa ttgattatat aattcctttg
    67501 cagcaacttt atctacatcc aaaacagctt taacaaaggt tgatacattt tcacttctaa
    67561 aagaacgtaa cgatacagat aagtgcaaat catcaattat tctataatta acaccttctg
    67621 ttaactcatc aaaagaatta cctttagaat attcttcatc aataatttta tttgatatgt
    67681 aaacatccca atcagaataa ttatttctta gtgattcaaa ccaacctgat attccatctg
    67741 actcaccttt atttatctct tgacctccac caatcaaaca aacaatagtc gcccatccta
    67801 tatgacgatt taaaatacta ataagaaatt caggctctga catattaaag tctaatacgc
    67861 ctttttttct tttcataaag ttagtcaaat taggttcatc ccacgcacgt tgtgcttcat
    67921 caaaaattgt gactctttca ataggtggtg tatcaacaga tatagcttca tctctaaaat
    67981 gatgaattat ctgaataaat tctttcgctt ttcgaatcgc ttcagatttt cgtattccat
    68041 ttctggttac atcatcacga gctagtgctt cttgtaaaac atcaactaat ggaccatttc
    68101 cagaaaggaa gactgcatgt tcattttcat ctactttttg tcgctcaatg gcaatattaa
    68161 ggccagcaag tgttttacct gctcctggaa ctcctgtgat aaaacatatt gattttctgt
    68221 tatgagtctt actatagtct ataattttat ttatagcttt agttgtttga tttaaatttt
    68281 tagcacttgc atcatttctt gaaatatctt caacattatg gcccatatat aaagcttgtg
    68341 cagcttcaat aattgttgga gttggcatgt ataacgagtt tatccaagtg tctgaattaa
    68401 atgaacttct attatatgta gtacaaatct tctttatgta ttttcctata ttaaactcat
    68461 tacaacaata agtttctaaa atattttcct tcatcattct tattctttgg tctttttgag
    68521 gggcttttgt acaaataagt attggtacta aaagtttatc atgactttct ttgtgaaaac
    68581 aattaaggtc aagggcatag tctgtaactt gttcaattgc atgcctagga taagtgtctt
    68641 catcaacttt aaattcaagg agaaaaacaa tgcccttgta aattaacaca ttgtcaattc
    68701 tactgcctat tcgtggtatt gtatactcaa ataataagtg tccatctttg aaagttgaga
    68761 gctctctttt taatattcca atttcctttt tccatgtatt cttttgtaag tcatcagccg
    68821 caaattgatc attacacgtt atctcaccaa atatagtaaa aatatctttg actataaatt
    68881 catttacact acttgaataa tatgctcttt tcatacatct tcccccttta tatctaatat
    68941 tcattttata gcctacatct atactacaat ctaaaacttg actcctatac tttataaata
    69001 cactacatag atatgtttat gtatggtact ttgataataa tttttctttg ctaagtacat
    69061 tataaactat ttaattaata tgttttttcc atatatgctt attatattat aaaatggata
    69121 gcgcatcatt taaatcattg attaaatctt cactattttc aagacctaaa cttattctaa
    69181 ttgtgtatgg tgacacattt aatgccttgg cttgttctaa agtcatttca tttaatatag
    69241 ctatatttgg agcaaatact aaactttcat ggcctcccca actcactcct attttaaata
    69301 aatctaattt atttacaaat tttttaacat catttacatc ctttgcgtct atttcaaaac
    69361 ttaataacgc agtataatta agcaactgtt tctttgctag ttctttttga ttaaaatatt
    69421 tagataatgg atgatatacc ttagtaactg ctgaatgatt atctaaaaat tcaactactt
    69481 ccttagcatt tttggtatgt actgataatc tagcgtgtaa agttctcaaa cctcttataa
    69541 ctaaaaatgc ttcaaatggt gctaattttg caccatataa agctaattca ctccctctta
    69601 tttcttctat atctttttta cttccaataa tacatccacc taccacatct gaatgtccat
    69661 ttaaatattt agataaagaa tgaacttcta aatcaattcc catctcaata catctttgat
    69721 ataatggtgt agcccaagta ttatctatta ctgtttttat attgtgtgtt tttgctagtg
    69781 ctacaattgc ctttatatct tgcattttaa atactgatgt tgatggacac tctaggtata
    69841 ttaaagttgt attttgtttt atagcatttt caaaatcttc tattctatca ccttcaacta
    69901 ttgtattttc tatatttcct ttctccttca attcctttgt tataaagttc attgtaggat
    69961 tgtataaatt atttgaagct attatatggt caccattttt tacaaaatga agtatagcac
    70021 ttgatatagc acccattcct gaaccaaagg ttatacttgc ttcagcatta gctaatgcag
    70081 ataactttgc ttctaaaata tcattagtag gatttttagt tcttgaataa agatatccat
    70141 cttttgaacc ttcaaaatat gcttctatat cttcatatgt acttcttgcg aatattgatg
    70201 attgatatat aggtgggttt acagctccat aatcgccatc caaattttct cctacatgat
    70261 tcattaatgt ctctatctta tatttatttt tatccatgtt ctaaatctcc ttatgaaata
    70321 tttttatata tgaaaaatac atttaacata gcttattttt tataagctat gttaggtaat
    70381 aaagttaaaa tattcattat gatactttat tagattgttt tttatccttt gaatttttat
    70441 atgtacctat ccctgtaact gctaagatta ctgctataat tggagttccc cagttcacta
    70501 tagaccaaag tgcgtattct ccaacattaa ctcctagtgt ctgagtgaaa aatattgctg
    70561 ctggtgtcca aggaaataaa acttctaaca atgtacctgt atcttctgta gttcttgata
    70621 gtaccctacg atctatatta ttctcatcgt atttatctcc aaatatacct gctgttacaa
    70681 aactacatgc tataccattt gcagtcattg ctatcattgc tattcctgtt aataatgaag
    70741 aacatattat agccgttcta gacttaaccc acccaaatat cacatttacc gttgctggca
    70801 tagcatcaat acttccaagt actccaacaa caaataatat agatgttgat attggcaata
    70861 atttacctaa ttcccagaag ccaccttttt ggaaaaaacc taatatataa gcttgtcctt
    70921 ctataggttt tgcatattca tgccaagtta ccatatctag tgagaatcca ctgttaagtc
    70981 ctataagaac atctgccaaa gaaaaacctt gaaagattac tgcaaatgca agtgataaaa
    71041 atgctgctat tgtcattact ggtattgcag gttttttcat tgctgaacct actaatacta
    71101 ttaaaagagg tataaataaa attatattga aattgaacat tcctgataaa tctgccaata
    71161 atctagttat ttctggacta tttaaatttg tatttgttgc tgggaatata aacccacaag
    71221 caatatatat aactaaagct attatagttg ctggacctgt tgtccataac atagatgcaa
    71281 catggtcata taaattaact tttgacgcta ttgcagctat atttgttgta tctgataggg
    71341 gtgacatttt atcaccaaag taagctccac ctactatagc acctgctata atagcattgt
    71401 ttgctcctat tgcattacct acccccatca ttacaactcc tatagttgct gctgatcccc
    71461 aggaagttcc tgtaaatgaa gaaaacaatg ctgacaatat taatgctgta gcatatacaa
    71521 atcttggatt tatcaattta actccataat atactaacat aggcattaat ccactcataa
    71581 taaatcctgc aataagtgga cctattacta ataatattat taatcctggt aaagctcctt
    71641 ttacaccatc taatccactt tcaaatactt cttcccacgt tttatttgtt gtaaccacta
    71701 taaatagcga tattattgat gctgaaataa acattattga ctctattggc aaactatatt
    71761 ccggcttatt gttaatcatt ggaagtaata gcccacaaaa taaaactgcc ataaacaaaa
    71821 ctatagatat agcctgcttt tgaattgtaa cttttctctt catttattat ttcctcccac
    71881 ttttatttac tcattaattc aatttttaat aacgttttcc cttatctaac aataaaattt
    71941 actatcttat atttatattc aacaatatat ttatatatat aaatatattg ttgaatattt
    72001 tattataaac tccagtttat tcttaaacta ttttcttaag tgaatttact ttctatatct
    72061 tttaatcacc tcctctctca tagtgtttta ttaattgtac ataataagtt atcatagctt
    72121 tgtttatctt ttatcttatc tagtacaaat aatcctctga tattgaaacc ttaaaatttt
    72181 ttgataagtc tctaaagtta tctcctgtta ttgtttgttt tttccctccc atagatatta
    72241 cttttactaa tatctcagcc gatttttcta ctgtatccat aagaccaaat gttaagtcca
    72301 aagtttctcc tgagcagaac gttccatgat gagcccagat tactatgtta tgtttttcca
    72361 ttagattttg tgtagctttt gctatctcta tcccacctgg caccatccaa ggtacgattc
    72421 caattccttc tggaaataca gctggacatt ctgtagccat ctcccataat tctcttgtaa
    72481 atactttacc ctcaagaggc agtataaaag ttaatgctat gagattagtt gtatgtgaat
    72541 gcattattac tctatgtaat ccatttgttt tgtctttttt tatagaatga ctcattaagt
    72601 gagatggaaa ttcacttgtt ggtttagcct tatctaatcc ccaaactatt gcataatttt
    72661 cacctttttc atctatttta acaattccta cattttgaac agtatttata gaaatatttc
    72721 tcatgaattt gccacttcct gtaactaaga aatattcatt agctaaattt tcgactgtta
    72781 caccaattgg aatatattct atttcttctg ttataaattc ttttattcca gatatttctt
    72841 caggtgttaa tctatacgtt atattccccc cattacgctc atgccatccc tttaaccaag
    72901 catcataagt tattttcata aaatctttga taaagttcat ttccattata gacatatacc
    72961 cttacctact ttctatttaa taattctgtt aattcgtact cttttactac ttctatccaa
    73021 tcttctttaa cagcaacatt attaatttta caataatagt tccatatgtc tcccattgga
    73081 tatgttttga actcttccat tatagccaat ctttttgtaa aatcgccttc gtcttgtaat
    73141 tttcttaatt cttcatgagg cattaacata gctgataaca atgcttttat catatttcta
    73201 gttccaatta cccatgctgc tatacgattt atacttgcat caaagaagtc tagtcctatt
    73261 attactttat ccaaagcatc atttcttact atttccttgg ctatttcttt tagttcatca
    73321 tctaatataa ctacatggtc actatcccaa cgcactggac gacttacatg aagtgcaact
    73381 ttatctgaaa ataatagcat tgatgataat ttatctgaaa caagttctgt aggatgatag
    73441 tgccctgtat ctaataatga aattatgttg tttttactag caaaatttaa gtaaaactca
    73501 tttgacccaa ctgtataaga ttctacacct aatccaaaaa cttttgattc gacacaatct
    73561 aaattatatt ctctgtttat ctctaccttt aatatttctt ctagtgattc ctttaagcgt
    73621 cttctaggac ctaatctatc acttggtata tctttgtatc catctggtat ccatatgttt
    73681 gttaaacaag tctgaccaag ctcctttcca aagtattcgc ctatttttct agaagctatg
    73741 caatgcttta tccaaaaatc acgtattttt ttatctgggt gtgacaatgt taacccatca
    73801 cttgattttg gatgagagaa tattgttggg ttaaaatcta atcccaatcc tctttcttta
    73861 gcccatttta cccaattttc aaaatactct ggttttagct catctctatc cacaaagctt
    73921 ccaccagttt ctgcatatat agcatgtaag ttaactttat gtttccctgg tattaaactt
    73981 aaagccttat ccaaatctcg tcttaactcc tgaggatttc tagcctttcc aggataattt
    74041 cctgtagatg caattcctcc tgatagtctt tgttgatttc cttcaaaccc tgttacatca
    74101 tcaccttgcc aacaatgaat agatatttta actttagata aaactcttaa tacttcctct
    74161 acatttattc cccatttttc atattctttt ttagctactt catacctttg ctttaattcc
    74221 atcacttatc tcctttttca gattaattat attgaattat atcaaatgaa tttcttatta
    74281 tatctctcgc ctgttctaaa tcatttagct cattcttagc aattaattga catactatat
    74341 tacctaatgc tgtagcttca acaggtcctg ctaatacctt tttaccactt tcttttgcta
    74401 taagctcatt taacagttca ttttgacatc ctccaccaaa tacacttata gtttctaatt
    74461 tttcttctat gattttttct atttcattta tagatttact ataacttttt gctaaactgt
    74521 taaaaataca atatgctact tctccaactg tttgtggttc tgtttgatta gtttctatac
    74581 agtattttat tatttcttgt accatatttt caggatttaa aaatctatca tcatttacat
    74641 ctactattga tttaaatcct tctgatagtc ttgcatgctc tactagttct gtaaaagagt
    74701 gcttactgtc ataacacttt ctagcttctt gtatcatcca taaacccatt atatttttta
    74761 aaaatctata tctatattca tatccacctt cattagtaaa attataatct aaagcctcta
    74821 atttgcactt tggtctttct aactctactc ctaataaaga ccatgttcct gaactcaata
    74881 aaatgcttct attttttaca ggagtagaca tgaaagctga acctgtatca tgagtaactg
    74941 gtaaaatgac ttctaaatca catcctaact cttctactaa ttctttcttt aaactaccta
    75001 gtattgtttt gggagttttt attttagcaa ataacatctt gtcaaatcca agtttattta
    75061 ttatttcttc atcccaatta tttgttgttg tatttactaa ttgtgtagtt gttgcatttg
    75121 tatattctgt aacttttttc ccagttaata aaaagttaaa ataatcagga atcattagaa
    75181 agctttttgc cttttctaat aaatctggct gttgattttt tattgctaat aattgatata
    75241 tagtattaaa cttttgaaat tgtattcccg tttttaaata tagttccttt ttatcaatta
    75301 ttttaaaggc ttcttccata attccatcag ttctattatc tctgtatgat acacagttac
    75361 ctaatatatt gtctttttca tcaagtaaca caaaatctac agcccatgtg tctatagcca
    75421 cacttactgg aattttattt atttttatac atttttttat cccatttttt atttcagaaa
    75481 atagctttga tatatcccaa caaaaatgac catctttttt aatcaaatta ttcttaaatc
    75541 tatatacttc ttctatttcc aactttccat tatttatata agagataata tgtcttccac
    75601 tagatgcccc tatatcaatt gctaaatagt atctcaagac ttttcctcct tagatttatt
    75661 tattaattga attatacaag atgttagtat attcatttaa tatctaaatt tgtcatattt
    75721 attaacctaa tttgcaatat aactttattc tcaataataa ttttcaaaat ataatatctt
    75781 cagagctatt aaaatggttt atttaataat aaaaaagaat ctattttata gattctaatt
    75841 ttactattga ctatttttta tatttttttt gtattctttt ggtgtaatac catacttatt
    75901 tttaaatatt ttataaaaat aagttaaatt ttcataacct acattttcta taatttcagc
    75961 tattgataaa ttagtagata ctaataattc acatgcttta cttaaccttt tttcttgcac
    76021 taaatcttta aaagtatatc caagatgttt ttttactagt ttacttattt tataatcacc
    76081 ttgattcaaa ttacttgcaa tttcagataa actacctttc ttgtagtcct tatcaatata
    76141 ttttagtatt tctataatca tcatcttttc ataattatct actgcatgat tttctacatc
    76201 ttcagaattt ttaactaatt ctactaataa taatcctact aataatttaa tctttacctt
    76261 attaaccaca cttggttcat acaattctat tataattttt tctattatat cttgaatctc
    76321 ttctttctca gatactttaa aatatatata ttctccaaga ttataattag tatataatgt
    76381 agtcattaaa aagttcatta ttttattatc attttccaac aaagatataa tataatcaaa
    76441 aaactctggt tttattataa aattaattat tatatcttct tcgtcactag cttctatttc
    76501 atgaataaca tgctgattta aaaatattaa ttctccttgt tttaaattaa ttttatattc
    76561 atctatagtt tgtactaact ttcctctata aacataatta aattctatat aattatgctt
    76621 atgttttgga aattgtgcaa atcttgtatg ttttcttata tgtatcaact catctatatt
    76681 caataatttg ttgctatcta ttataaattg agaattatca gtataaatac ttttatctat
    76741 tatataattt ccttctaata tatttttttc ttcttctgtt atttccctca acttatcatg
    76801 aatatattgt ctcatgagct acctccttag ttagttcaac tactagttgt ttcaatttaa
    76861 aattattttt agcattaaat atataataat tatcacatct ttttcctttg tgtatagttc
    76921 ctgataaaaa attatatatt aactcattag atgaaactct ataaagttat gtttatgttt
    76981 gggtatatct ataaatctac gatgtttaga tattataatg tcttcatcta aagaaagtat
    77041 atttttatct gttagtacta tagttccatt tatttcttcc caacataaaa tagtatgcaa
    77101 tatagacact atttttttat tatctagttt ttttacattc ttagtaacta tgtattctaa
    77161 gatgtacctt tctgcttgtg ttttttgttt aagtatatcc tctagcgttt catctttcat
    77221 ttatatcccc ccagatttag ctatacttta ttacagtttt aaattatatt acaaatattc
    77281 tttatctaat tgtatcatat tagtttttga cagtaataat gttaaattat gacatttaaa
    77341 aatacctttt tttgttttaa aatacattta taggtaaata cttaaaattt aggaggtatt
    77401 tttttatgaa tacaatacgc aaatgtttca agatgaagct ttttaaagga tttgaaaatg
    77461 aatacaagaa acgtcatgat gaattatggt ctgagatgat agatatgatt catgaatatg
    77521 gtggtagtaa ctattctatt tttctagatg aagaaactaa ttatttatat ggatatatag
    77581 aacttaaaga tgccaaacta tgggataaaa gttcagagac agcaatctgc aaaaaatggt
    77641 ggaattatat gtctgatata atggaaacta atgaggataa tagccctgta tctatagaac
    77701 ttaaatctat gttttattta aaataaggac aaaaattatt ataaatcaca aaatggggat
    77761 atatcaaaat aaaaatttga attatctcct ttttgtataa aaaagataag tgattcctaa
    77821 aaacctctag tctatgtgat aattgttctg tgaaaaacta aaaacatatt tcgattatag
    77881 tagctaaaga tgttataaac aagtggtatt tctactagac attgaaacaa ttattcccaa
    77941 agatgattca gtaagactac ttaactttag aataattgat atatcttgtg ttgtttatat
    78001 taaattttta atttaagtaa tagtatatgt aatctttagt catcttctta ccagtttttt
    78061 atccactttt ctaatgaagt tattttttca tatgttaatt cctcttgaaa taatgatact
    78121 aaaagacttt ttataaaatt ataacttaaa agtttatata tttttttgat atgaatttat
    78181 agtacttatc ttctttaatt gagattgtgt atatttaact aaacattaca acaataattc
    78241 tatgaaatca aatcaattat ttacatattt ttttagaaca ataataagta tatattcaca
    78301 aaattttgtg ttaatatttt tagtttgtga tataataaaa gcaaggaaac atattttact
    78361 taactttgag tgatgtttcc ttcaacaaat tattttgaag atttactttt ctggaacttt
    78421 atattaagtt cccagccact cttagttggt cgctcagagt ggctctttaa tttatcgtaa
    78481 atgtaactgg ctataacacc agttataata ctcatcatta gattttccat agttttcacc
    78541 tcctctcata agaaagtgaa gaaacttcca tggaaacacc actcatagct ttttcaaata
    78601 tttattcctt gccatattaa ttatatcata aatattggaa acataaaatt ttaatactta
    78661 tcgtctttat tattattttt tataattaat aattttcttt ttaataatac ataatataaa
    78721 tttatatttc ttcaataaaa aagacaatct taattaattg tcttttttaa tatatatttg
    78781 gctaatacat tattttacac aaacattaca agggtctatt ttaccttgtg acttagcttg
    78841 ttttaatgtt actttattta ttgttttact tctttttagt gtagaacaat tttttgttag
    78901 atgatatgat tttccattag gagttacata tactgtactt ttatcagtta atccaggatt
    78961 attagagcta ggctcattac ttggtttgtt cgtattattt gaattagtat cttttacaat
    79021 acctgtattt gaatccccaa cattattagt tatatttaaa cattatttta taacaacatc
    79081 atcaatattt ccaatagcag ttattttact tgcatttttt aatatactct tattacttcc
    79141 atttccaact aacactatag gtgttttttg tgcaattgta gaaccaacta aagaataaac
    79201 taaatcagtc ccacttgcta tgtaaaattc ttttgagcca ttataaaatt tatttattat
    79261 ttgtttattt gtatcgtatc tatctactcc acctattctt gttgctttag tttcatttat
    79321 taacttatca ctcatactga cttttccacc aattgcataa gtttctaatc catctgtagc
    79381 aaaacttgta gtatttccat cagttaatac tattggagat ttatctctaa ctgctataga
    79441 agcaacactc atagcatctg gttcgccttt aaaagcatta gttaatatta cttttttaac
    79501 cgtacttact cttcctattt cttttgcaac tttatgactt gtatctattc tatcagttcc
    79561 acttattcta tttatgctta tttttttatc acttaatatt ttctgaactg atgctcctat
    79621 cgaatttttt cctccaatta gatatacttc ttttaccttt tctaatcttt ttaatgtttc
    79681 tgaagggatt gtatctttct tagttaacaa tattggggca tttttagctc ctgacaatcc
    79741 acttgctgac aatccatcag ataatccatt ttcagaatta ataagtattg caatatcata
    79801 attttgttta tctgctatta aacctgctgt ttcatactta tttgtacctt ttattgaatt
    79861 aatagaacta agagcgtttg atgttggaca actagcaatc aataatgaaa cagacatccc
    79921 tattgccaat agtgttttgc ttaatttcat aatgaaatcc tcctataaat tttataatat
    79981 tacttaaata ttataatttt acataaaaga atattttcct ttatgaaatt agtttatatt
    80041 tcaaaatttt gtcacttttt aaatctatat actaaaaaat agactatttg taacagtcta
    80101 tttcttagta tatcaaatat ttatttaggt ttacgtttct ttgtactagt ttttgtatat
    80161 gatattccag ttccaggtat actcaatgta gctgattttc ttccttttga attaactgac
    80221 actctagcac ctttaacacc agcacttata cctacactct tcttacctaa atttaatttg
    80281 agtcctcctc ctagatttat gcttttccta aagttaaatc ccatagatat aaccttccct
    80341 tctatatttt aaatatttat acttaaaatt atatttgtta tacacttgtc atcattggta
    80401 tatctagcat ctatatcttt ttacgttttt tcttcttata tactactcca gcaactacag
    80461 ctgctattcc agctccaacc ccataagtag catttctact tttctcttcc tctctttttt
    80521 ctaaaccttc atcatataca ccttttaact tagtttcaat agacttcatt tcatctggta
    80581 tactaaaatc ttcttcattg taaccttgat tatatacact ttcttttgct ttaggtaact
    80641 taaccttacc attatcatat ccttctttaa accaattagc atatttaaca ttacctatag
    80701 ttgatgtgtc aaatctttct cctttgatag cactctcaaa tccttgagta gtgtaatcat
    80761 tttttaattg ttcttgtatt tcgtcataag cattattata agcatctata aattcagaat
    80821 ctatgttttc ttcaaatgtc attttttctt tatctttatt gctatcctct atccctttag
    80881 ctttatattc ttctatcttt ttagtcttat attcattgta tccggttgaa tatccggtat
    80941 cataagcatt ttttaaaact tctttttcat atgtattatt agatttagca cctgtaagcc
    81001 ctaaattata tccagtctct ttagccacct tttcttcctc ttctaattta gccttacctt
    81061 tttcatatcc ttctgagtac tttgattcat atgtatcact ataatctcca ctataatttg
    81121 atgaactata atttccttta tatccatctt catacccttg attatatcct ttttctccaa
    81181 cagacctctt ttgcttttct tcattattaa ccgaagttgt tgttccagaa ctgcttcctc
    81241 ctccagtata aggacaacca ccattattat gtaaatgagc tggataacca ccacaatgat
    81301 agtgataact tcctaatcca gatttatttt tattatcacg atgacctcct gatgaatcag
    81361 ttcttcctga atgagcatac gaaaagctcc ctacactaat catagttata ctcattgcaa
    81421 cagctattaa ctttttctta aacataatct atttccccct aaaatattct atgattttat
    81481 tatatcagtc aatatattat gtttaaaccg ttaaaattcg acaatgtaaa tatttgatga
    81541 attgtatttg taaataaatc ttttagcata tcttgaatat ctgtagttgt tttgacatca
    81601 tattcttcaa taagtttttt aatatttcgt ttttgttaaa cataaaaagc gtgcactttc
    81661 ctttgtatag tgatatttga tattttaatt atcactactt tagaagaata cacactttat
    81721 tttaaaaacc ctgatactat gttattagaa aatggtacta atataaaaga tatccagcat
    81781 atactcggac atgctaaaac ttcaacaact atggatacat atttacatgt aactaataac
    81841 atgagaaacc agacggtaaa tatttttgaa atcattgtag aataaatttg ccacccaaaa
    81901 ataattatgg tagcaaatct acttttaaga cacactataa aagtctgaaa ccctgttatt
    81961 ctctaataag tttaactaca gtctcacaat gcgttgtctt ttgattggga acataatttt
    82021 ttatcctcgt cattcttgta ggaacacaat ttattaatgt cattgtcttt ggcatttttt
    82081 cttttatctt taaagttatt agaatcttga ctatctttaa ctcctgtttt gaagtaaaat
    82141 gttaagtcat aaggatgaac tgttccgtct ttgtcaattc ttcccaccac gactttatca
    82201 actatgcttt caaatactgt tctgttaaat tcctctataa tttctttatt ctctaagacc
    82261 tttttaaatt gctttaatct ttctttaata gagtcttcat cttttatcgt tagttccaat
    82321 gttttctttt catcgagtaa ttcttctttt tgctttgtaa gttttttata ctttttagca
    82381 taaacttctt cgtctatact atcttctaaa tgaagatcaa ctaactttct ttcttgacta
    82441 atgattctgt ttaattggtt ttctaacttt ttcaaatctt tgactaacgt attatcattt
    82501 atttcttctt caacaatttt taaaaagtca tctattactg ttgaatctgc atggcataat
    82561 tgcctatagc tttcaacaaa tgctttttct attgctgctt cttgtattcc ctttgaatga
    82621 gggcaatatt ttttaccttt ttttgttgac tttacacatt gccagttaat ttttttataa
    82681 attgaacttg tatgccatgt tcttcttgaa agtatctctc cacaaaatcc acattctaac
    82741 atacttgaaa aagcgtattg ccttgatagt ttttctctct tcctatcctt attagcaatg
    82801 gtgtttctat tttgtgctct cctgagtcta atctcctgtg ctttttcaaa atcttctttt
    82861 gatataattg gctcgtgatg attttcaatg tggtatttat cagattctcc aaaatttgct
    82921 agtcttcttt ttgttattgg atcaactgta aaagtttttc ccattagtat atcgccaata
    82981 tacttttcat tcttaattac ccctaacact gtagtatcag accattttgt tttacctcta
    83041 ggggtgagat atccttgttc ttctagttcc ctaccaatga ccgaaccacc attgccttct
    83101 aaatatcttt taaagatata tctaacaatt ttggcttctt cttcatttat agagatactt
    83161 tttgttatag ggtcatagtc gtatccaagg caaccttgaa aaccaataag ttcccctttt
    83221 tccattttca ttttcagtcc tttttttaca tgggctgagg tattttctac ttcttgttga
    83281 gctactgaac ttaatattgt tagtaatagc tctccatcca ttgtcaaagt atctatattt
    83341 tcttcttcaa atactacacc aacattattt tcctttagaa gccttacata tttcaaagta
    83401 tctaatgtgt ttctagcaaa tcttgatata gatttagtaa ttatcatgtc tatatctcca
    83461 ttttgacaat cactaattag tctcatgaaa tctgctcttt tagtagcagt tgttcctgtt
    83521 gttgcttcat ctgcatatat accagccaga gtccagttct tattattttt tattagattt
    83581 gtgtaataat caacttgcga tttatatgat tcaagttggt ctttactatc tgtacttact
    83641 cgacaatatg ctgcaacacg ttttaaatct aaacgtagtg catttctatt tctagctcct
    83701 gtatttgaag cttttattaa ttttacttta gtattcattt tacctccttc ccattttgta
    83761 tctttctaca gtgttattat atcacaagat taactacttt ctatctctct tcttataatc
    83821 attttctatt ctatttttta tttttgcata ttccttatca ttaattaatt taagatcata
    83881 aagcctacac aacatagcaa ctctcatgct ataaatcttt attgctttca taataacctc
    83941 ctatgtaaat ttaagttttt tgacattgac aagtgccttg gattagcaac ataggaatct
    84001 cacctccgcc tctgttcagg atgagccggc ttcaacctta gaagtatcat tatcctcatt
    84061 ttcttcatag cgaatagggt atccctccct atattcaaac tcttacttat cgctcccttt
    84121 cttcttccct tgcttttagc ttagcagtac ttgttttgcc gaattattca gcagaaagat
    84181 cttggcggat aggttatcac gctccaaaaa tgattaacgt cttgtcttgg tctattcaat
    84241 tgttaaggtt caaaatttat cgagagttat taatcttttt aaattttgac catcagaaaa
    84301 tacttatctt gatgaaacaa aattgtttaa aattaccctc ttatacttaa cagtgaaaag
    84361 aagtctttct tggtaaccaa ttttcaaaaa taaatttggt taaataaaaa ggtccaattc
    84421 ccactgtata agtaacagtg aaaattagac cctcttggca attgtcatct aaaagtcttc
    84481 caacatttcc tttagttttt ctaagacttt attacgcctt ttaataacgg ctggatgaga
    84541 aatattcagt ttagcagcta cttctctaat tgtttcttct ttataaaaaa ggctttctat
    84601 taggtctctt tcaacaggat tgagtttata aatagctctt cttacttctt caatcatttc
    84661 ctttgtttcg ataatttttt caacatcaaa ttccagatct tctaaatttt cttcaaaatt
    84721 accatcatga tcataggaac aaaaaaagaa acagttattt aacctgtctc ttctcatttg
    84781 atatttctct ttattcaatt cactatgata agcaagatat acctctttgc taacaactac
    84841 tttcttccct tctacaaata aataatattc tttgtccatt aatttttcct ccttgttgac
    84901 ttgaatttct gttatataaa aatgaaattc acacaaggag ggcttctaat tctatgcata
    84961 tactctcctg ggcataaaaa aagaccgaaa gaaaataaat tctttcagtc aataaatgcc
    85021 aatattaaat ttaggtgcaa atcacccatc atggatatta tatatgcact taagtacaca
    85081 taaaattcgt atatggtact tttttcattc ggaaatagta cgcaataagt tcgtcataaa
    85141 ttaagtcctt agatgttcat tatttcttca atgctacgac catctttaag ttggctaata
    85201 gcagtcggta aagtatatcc ccaaattatt acaccaacca atgcaattgc ttccttcttt
    85261 ctttgataat aaacagttct ctctaaagat acacttctca tacaagcttc atcagtaatc
    85321 tttttttcag aaatgtagta gttataaata atcttatgat agatttctcc atattctgga
    85381 taaactttta acctaacaca ggcatcataa attattaaaa gtataagctt actatccatt
    85441 acattggaaa ctctattatt aaacttttct tcaactcttt ctggagcaaa tgtagaaaga
    85501 tacaagtaag cagattctga agttgaccca tagttttctt tactctcaaa catcataaaa
    85561 tttgccctgc tatctactgc ccaagtaact tgtctatata aacttaaaat gagttttgca
    85621 gctgaactaa tttcttcaaa tttcaagtcg ctatctgcat acatgttcat tatattcttt
    85681 aaagttttac ttattctcaa tctaatcacc ccaatacaac ttatttacaa acttgaatgt
    85741 ttgtgctata atatgaatat aagttcagtt tgtattatat ctcaaattga aaaataattc
    85801 aagcactatt gttcgtatta aaagttataa atgcacatta gtacaggagg ttaaagttat
    85861 ggcttttgcg gatagattaa aggattttcg tgaaaaagaa aaattaagtc aagcagattt
    85921 tgcaaaaatg ataggaataa gtacaagaac tcttgtacat tatgaagacg gagaaagata
    85981 cccaagagat gtcgaggttt acaaaaaaat agctgaagtt atggactgtg attacaatta
    86041 tcttttagaa gaaagtgacg agtttttaaa tagagtttat aacatgggtg gcaaaagaga
    86101 attagaaaaa gctagagcat taacagaagg tctaagctct ttatttgctg gtggagaaat
    86161 ttctgacgaa gacaaagatg ctgcttttga agctattact cgtgcttatt gggaggctaa
    86221 aagagaaaac aagaaatacg gtcgtaagaa aaaagattag gtgattttat gagcatgaat
    86281 cgctatatat atgataaggt taatcgactt ataaaaaaat ataagacacg agatcctatc
    86341 gaattaatag aagctttgaa tattaacctg gtatatctac ctgaaacaaa aatactttta
    86401 ggaatgtacc attatattca aaggaacaga tttattttta tcagtagcaa cacaaatttt
    86461 aatagaaaga ctatattagc acatgaatta ggtcacgatc aacttcacag agattattgt
    86521 atgagtggcg gagctttcca tgaccaaaca gtgctaaacc ctacaaataa atttgaaact
    86581 gaagctaata tttttgcagc tcatttatta ataagtgatg aagatatcct agataatatc
    86641 aatgatcaag tttgtgatta tgaaatcgct ggacagttag gcgtagatat aaatttacta
    86701 aatttaaaaa tttctgagtt agcaaaaatg ggcaagttta ataaaccagt taatgttaat
    86761 atacctcagg gagattttct taaaaattat cgccctgaac atgatgatta ttattaggag
    86821 actctatggg aatttttatt gcaggatatt ttttattaat cctttctgga atagttttct
    86881 attatctcat cactacctac tctgtaaaaa tttcagcatt tttaattgat tttatagttg
    86941 taggtttagg attttacata tccataaaag ataaactaga tagcaaatta gctattcccc
    87001 tttcaattac agtagtaata atttatggaa tattgctagt tttaataaat cgaaagctac
    87061 caaaggttag cagattttta aactatataa ttgcttttat aggctcatca gtcgccctat
    87121 ggttggcact tgattttata acaaacactc tagccgcttt taaaataata ggtcaaactt
    87181 atcatcaatt accaataaca aaaagtatga tgataaattc ctttatacat tatgtaattg
    87241 tattcttgat tagtattcca gtgtttaaag gtagaatgaa atttatactt ggaggaaatt
    87301 atgagtagag aaatggataa aaataaagac gaaaatcaga aaaaaaaaga acttcaaatt
    87361 aggtcctctg ctgctgaata cttgactttt gttgcagcaa atggtgatga tcaagaagct
    87421 atcgaaatta gatatgaaga tgagaatatt tggctaactc aaaaaatgat ggcagctctt
    87481 tatgatgtaa gtgtatcggc aataaatcag catctaaaaa aaatatttga cgataacgaa
    87541 ctagacgaaa attcagttat taagaaatac ttaataactg caaacgacgg aaaatcatat
    87601 aatacaaaac actataacct acaagcaatt attgcagtag ggtttaaagt aaataacgaa
    87661 cgtgctgtcc aatttagaaa gtgggcaaac caaattgtaa aagattttac aattaaaggt
    87721 tgggcaatgg atgatgaaag actcaagaat tctggcacaa aacttaccaa ggattatttc
    87781 gaaaaattac ttgtaaaaat tcgtgagatt cgattatctg aaagaagatt ctatcaaaaa
    87841 atcacagata tttatgccac ttctttagac tatgatccat ctgcaaaagc aacaaaaaga
    87901 ttttttgcag ctattcaaaa caaattgcac tatgcaattc atggaaaaac tgcagctgaa
    87961 ttaattgtag atagagccaa ccacaaaact aaaaatatgg gacttactac ttgggaagga
    88021 tctccagatt caaaaattca taaatatgat gtagttgttg caaaaaatta tctaaatgaa
    88081 gaagaattaa atcaaatgca aagaattgtt tcatcatatt tggacatggc agaactacaa
    88141 gcagaaaggc atatccctat gactatggaa gattgggaaa aaagattaaa tggattttta
    88201 caattatggg ataaagaaat cttaaacgat gcaggaaaag tgtctgcagc tcttgctaaa
    88261 aagcacgcag agagtgagtt tgaaaaatat agaattatac aagatagact ttacaaaagt
    88321 gattttgata agttcttaga actagaaaat gatactaaaa aattagaaga ataacttaat
    88381 atacgcttaa tgcttataac tttaatagca agcacagtaa gtgagtaccc actcacgaaa
    88441 aattgatgaa gcagaacctt tatggactgc ttcttttttt tatcaatttt accttgttag
    88501 ggagaaccct aagaccccaa tattttatga taaggagata tactatggat aatagaaaaa
    88561 gaaataatca actaaaaata tatttaacag atgaagaaaa agaaatattt gaaaagaaaa
    88621 tgaaacttgc taattgtaaa actatgtccc actttcttag gaaatgtgta ttagaaaaag
    88681 aaatttatgt agtggattta gaaccattca gaaacctaca atggctactt tcaaatgcaa
    88741 caaataatat aaaccagatt gcaaaagcga ctaatacaac tggtgttatt tacaaaaatg
    88801 aaattgaatc aatgaataag cagatagaaa aattatctaa agaaatatgg cagatccatt
    88861 ccctacttct taataaatca aaagaaagtt ctggtgatta gtatggcaat tacaaaaata
    88921 catcctataa aatcaactct aaatttggca atagactata taactaagag tgaaaaaact
    88981 gatgaaaaaa tcttggtatc ttcattcaaa tgtcatccat ctactgccca tattcaattt
    89041 atgaaaacac gagaagataa tgatactaaa ggtacagttt tggctagaca tttaattcaa
    89101 tcttttctac caggagaggt tgatcctata aaagctcacg aaattggaat ggaattatgt
    89161 aagaaaattt taaaagaaaa ttatgaattt gttcttgcaa ctcatataga tagagggcat
    89221 atccataacc atattatttt taataatgtt aattacaaga ctggcaaatg ctaccaatct
    89281 aacaaaaaat cttaccacaa aatcaggtat caaagtgatg aattatgtaa agcaaataag
    89341 ctttcagtca ttgataaata ctatgaagct tacaagagaa aatataaaac tgctggtaaa
    89401 tcttggtacg aatatgacca aaacaagaaa ggaaattctt ggaagtctaa actgcaattt
    89461 gatatagata gagtgattaa taagtctaac tcgtgggaag aatttttaga aaatatgaaa
    89521 tctcttgatt atgaaattaa gtttggtaaa cacattgctt ttcgtcataa agataagaaa
    89581 agatttacaa gagctaagac tatcggagaa gattatactg aagaaaagat caaagaaaga
    89641 atagatttag ctataataaa taaagctaat cctattaaaa aacgagtagg aaatgttatt
    89701 gatatatcta ctaatgaaaa agcacaatcc tctaaaggtt acgaagtctg ggcaagaaaa
    89761 cacaatatca aaacaatggc agattcaata attaaattaa gagaacaagg cattaattcc
    89821 attacccagc tcgatgatct gatcaaaaaa tctgctgatg atagacaaga cttattagat
    89881 aaaataaaaa aatttgaaac tgagatgaag agtttatcca aagatatgga aaatatttat
    89941 actataaata agtatcgtga aatatataaa taccacaaga aaaatcctga agataagcaa
    90001 tttgaagagg agtattatag cgaactttcc gtctataaaa tagccgctaa agaaatctta
    90061 gaaaattata ataagctacc aaatacaaaa gaaatactat ccaagctcga taaactgcaa
    90121 gaaaaaaaga acacccttat gcaagagtat tctttgaata aagaacaatt ttctgacctt
    90181 gttcagtata gaaaaaacta tgaaaattat tatggaaagg aagtggagag atagaaagct
    90241 ataagtggat aaacttatag cttttttaaa attatttaca aatttttatt ctaaacttat
    90301 tatcttactt aaagagatcc tactagatga ctagcaaaca ttgctatagg aagtaataag
    90361 ataaaaagga catttaatgc cataaaaaac ctatcttttt cccttacccc aagtattaaa
    90421 cctactagtc caataattgg acagacaagc atgtgagaat aagcaataaa tacgcatctc
    90481 ataatttatt atatcatttt ttataaaaga aaaaacagcc cacaaaaagc tgtttaaatc
    90541 ctctaattga acaagttatg atactagaac tgtaaacatt acataggaag taataagagt
    90601 gttggtaatt taacactata aataacttgt ttttttcttt cctctattat tccatgctat
    90661 tctcctgtaa atatccccac atatagagca gtagacaata cttgaaaggg agtatttact
    90721 ggaatagatt cttcttttcc ctttgccact taccatatta gctcgtctat ccatttcttc
    90781 ttagacttgc atgaagattt cttttggtat gatcgcttcg tggctatttt ctatataata
    90841 ttgaggttct tgatcctcaa tttattcttt aattataatt aagatattta tctaaataga
    90901 aaaatggctt ttaggatttc ttctaaaacc ccaaaaacca ttaatttcaa cacttttata
    90961 gcctattatc ttattttcct tgacatcaat accaccgtct ccacatggct tgagaggata
    91021 gaatgaatgt catttgagtg tgtccgttct cgggaacata tccactgcgt ttttggggct
    91081 atcggtagac gggaacatat caatacacct catggattat tattttagaa tggattttaa
    91141 gtaatctaat aaatctgatt tagttagagg ctctgcatga cttaaaatac aatacttaca
    91201 gtcgaaactt tctatcaaat ttgttaatga cattaatttt tctttatcca tatacccatc
    91261 attgtagaaa tcctcgcttg ttgaatctcc caagaacaat attttttcct caggaatata
    91321 gataagcacc gtatcttccg aatggggtga aaccgtatga aaaatcattg cggttattcc
    91381 accgagatta agggtaagct ctttttcaaa ttggatatcc gatagaacgg caataattct
    91441 tttattatct acatattctc tagctaggca ctcatcatca tttatcaaaa attttatata
    91501 tgcactgtca gatagtttgg ctctttcctg tttcaaaaac tcgttggttt tatggtgtgc
    91561 aatggacaat ccgtgaattt tatgcattcc aaaggtatgg tcccagtgcc aatgagtgat
    91621 gacagtaaaa tctggcttct ttaggttctc gatttctagg gatttataaa attcatcaac
    91681 atggtctgct gaatttcctg catcaatggc aagtgcaatt ttatctccat ttaagtatgc
    91741 caacataggc ctatcagttt ctggttgatg tggataataa aaaaccctgc tagttatctt
    91801 tttcagttcc atttgccatc ccacctttct ggtaataaat ctttcagcaa cacttcttcc
    91861 atttcaggta atacaatttg ggtctctata ttttgattat ctatctgtgc aataaactct
    91921 ctgcaccttc cacatggtgg aagtatactc ccatcttcaa atacagcgat aatccttttg
    91981 attgcagttt cattgttctt taccatttca gcaatagctg actgttcagc gcataagcca
    92041 atagaacagg gcaagtcaat gcatattcct gtaaagatgt taccgctatt tgtctccaac
    92101 gcgcacgcaa catgccctga agttccaaag ttccgtaact ttttatgatt aattatactg
    92161 aaagcaattt gatataattc ttgtttattc attttcttct ccaatattat ttagcttaat
    92221 aatacgttat tcttttttca aaacactaag ttattcagtt caccatcaag aacttttata
    92281 gtttcatttc tttccttatc ctcttgattg tcatataaaa gttgttcaat aaactcccat
    92341 atatcttcta gtttacgtct aatatgatag aataacaaag catccgtatt gattaaaaaa
    92401 tctttgtgta atttcaggta tatgttcata aatacatcat aatatggctt atcaacaaaa
    92461 aacatgagat cagcttttac tggagccaat ttcaagcctt cccagtcaat tagaactaac
    92521 tgctcatccc gttgcatcaa gttccaatta tgaatatctg tatggcatag ggccatttta
    92581 ggattacttc gtcttagaat ctccgacagt ccttcaactc tgtcaataga ttgttcaagg
    92641 ggttttatgt gtgccccaag caagcatttt aagtccatgg gaagactggc gcattcttta
    92701 cgcaatactt gttttagctg tttcagaaat ggcaagctaa aatcttccct aattagttgc
    92761 acatatacct actatatcaa taaattttga gttatcattg actatattag ttgctattat
    92821 cagaatagtc gtcgataact atattttcgt gcaaatatgc aaataagtaa aatgatagtt
    92881 atgttatatc ataataattg aaaataatag aatgcatttt tcaatgtaat aagattaagc
    92941 gttctcttaa agttagagaa cgcttaatta tttttaattt attgaaataa tttgtaacta
    93001 ttgaaaacag acaaaaattg ttcattggat aatttatcaa gatcagtaac attcgcatgc
    93061 ttcagcacct gtcttaattg atttttagta aaaagaacat gatattccct gtttacccat
    93121 ttataaacga aaaatctata ctttttgtag tccttcttta aaataaatgg tttatgcctt
    93181 tcaagtacaa tcaatacaga atctacatta ggcttagggt gaaaatatgc tcgtggcact
    93241 tttttaagaa tttttatatc catttccacc attaacagca aacctaaagc tcgttgggta
    93301 ttttgcaacc ttttagcaaa tcccctctct acaataaggt agctatattt cgcttgacta
    93361 tcaaaagcaa tcttttttac aatatcagta ctaatattgt agggaatatt accaaatatt
    93421 ttatagtctg tatttttagg aaagctaaac ttcaaaatat cctcatgaat aacttttata
    93481 ttctgaaaag gttcaactgc ttttttcgtg gcatgacata aaccttcatc aatctctata
    93541 gcattcaccc gttgactcat ttccacaagt tccttggtaa aatgtccttt tcctgaccca
    93601 atttctatta ttttatcttg tttattgata ttcgtatatt ttaatatttc ctttacatgc
    93661 tttttagatg taatgaaatt ttgcgtattt ttcgggtttt tctgtttcat tataaccttc
    93721 tccttgccgg ttataatgaa ctaatcttaa gagctcatta taaccaatta tttttggttt
    93781 gattgataat taaatctctc aataacaaat atagaaaaca tacccatacc tttacctcct
    93841 ttaatttttt tcattataaa tgagataaag taatatctac tactgcaata catgtacaca
    93901 tatttaactc ctccttatgc aactgattat atcactttta atttctctat tcaataaagt
    93961 tctgtgctaa tctacctcac cctatggatt tttaatcccg aaacatcaaa tgtcatctgt
    94021 caaatgccct atttaaaagg gtcaaaaaac ggtatttttt agcctatttt tgacccaatt
    94081 ttcgtactca aaccactaca tgttgtggtt gactcctatt attccttgtc caaaccacaa
    94141 tacgtcatca gaattgctgc ttcaacgtgg gacgagttga tagaattgat gtatttatga
    94201 tttttagcga aaatgttgta tatgggaaca tatcgactaa tttgtacgtt cgtgagaaca
    94261 taacgactag ctttctaatg gtcgccaaaa gaatcgaaat ataattctag tttagaatac
    94321 ttctatcctt atcaaatata tgaaactgta ataataaaat ttaattgctt tcatcgacta
    94381 atgttaaaac ctacaacaca agaatttaaa tcattagatt acactattta ctattcaatc
    94441 aatttaagct ccttcattca tatcccttct actatacccc aaaaaaccta ttactattaa
    94501 agcaatgcta attatagtaa ctgtaagaaa aactgatgct tcaaaatcat ccattggcat
    94561 ttgaggcatc caactttgta tagcagtatt taaaaaccat tccgggaggt ctattaagcc
    94621 gctaaaataa tttaataaaa aagagaatgt aagataaata tacactattt tacctagttt
    94681 cggtgcccat ccaagagcta acgctgccag acctataaag aataaaacag tagggaaaag
    94741 gttaaagcca gcagcaaaaa agtcaactat atccatctct ccgctattcc ccatcgcaga
    94801 gatagcagta cctccaagac tacctgctgc taataaaact cctaataatc cgcttaatat
    94861 cgataaccct atactagtcc aatataattg actgcgggtt acttttgttg cataaatctg
    94921 acttaagtgt aatcgtcttt cttcagaaaa gagtttattt acaatcgcaa ttggtagaat
    94981 ggaaactaaa ccaatcaaaa ccatcataac tgtgcctgtg aatgattctt caatagaaaa
    95041 tcctgtatga gaaaacattt gtttcatcat ttcattactt tctaggaatg tctgcatatc
    95101 tccataaatc gaaccatagg cagcacccat aacaacatat gcgattaacc aactaataat
    95161 gacaccttta ttaatattta taaataatcc tcggacggac agcaaagact gctttgcact
    95221 ttcacgccct tctctttgcg gtaaatatcc agcccccata tcgcggccac cttcaagtga
    95281 aaaagctatg aacaccacta ttatactgaa aattaaagca aaaataagtg gaaaccaatt
    95341 attatctgta aaaggaaaag ttaaatatgt ccagcccaaa ggattcatca tagataagtc
    95401 aacattggag acatctgttc cagcacgaac aatgtatagt aagcctacaa ttcctaatga
    95461 tgatcctgtt gcagccgatg acgtgggcat aatttgtgcc attattagag caatcccagc
    95521 accaataatc cctgccattc caattgatgc cccgtataac acggaaccaa aaatagaaat
    95581 cgtatcggca ccgaaactta tcattactac tgcaataaaa agtgctagta taccattgat
    95641 aaagactatc tctgctattg ctgcaagaga atttgcctga cgacctattt gaaaggaacg
    95701 cagtagctca gtaaggccaa gatcttcttc tttacgagta tgacctatca cgtgtaaaat
    95761 agacattatc atcgcaaaca aaccacaaaa caacaacatt tcatgtgcat acattgctcc
    95821 taaggtataa tcagctcctg tttcaactgg ggtcggccct accatagata tcattgcagg
    95881 gttttgcaaa gtttcgaaca tgccgactaa accttgccct tttgctattt ctttgaaagc
    95941 tggaacaaat ccagccgaaa acatgccaag tcccaatacc catataataa tttttttcca
    96001 atctcgtttt aaatactgta aaaacaatat gttccaacga gcaaattttt ctttcataat
    96061 aatttttcca ccttcccacg gtttagcttt cataatgacg cataaacaaa tcttcaagtg
    96121 ttggcggtat agattcaaac cttgtgacac ctaatttgct agcttcaatt aaaatactat
    96181 tgagatattg attatcgaca gagaatgttg cttggctatc attttgaaca aaatcatgta
    96241 ctccatctac aaaagccatt tttgatacat ctccacttgt cactaaagtg acagttgacc
    96301 tagttaaatg tcgtaattca tcaagggttc cagtttcaac aatttcacct tggcgtataa
    96361 ttacaacctt atctgctaat cgttctacct cacttaaaat atgggaggac aataaaatag
    96421 ctttaccaga tgctttaatt ttttcaactt cttcttggaa aacttgttcc attagaggat
    96481 caagaccaga tgttggttca tcaaaaatat ataaatcaga atcaacagat aatgctgcaa
    96541 tcaatccaac tttttgacga tttccttttg aatatccttt ggcttttttc ttagggtcta
    96601 attcaaaacg tttaattaaa taatcgcgct tttctttatc tccactacca tgtaatttaa
    96661 tgaagagatc gataatttct cctcccgtta aagatcccca aagggcaaca tctccaggga
    96721 cataagaaat tcgcttatga atttcaaggc tatccttcca aacatcctta ccgaatatct
    96781 cggcaatacc agcatcacgt tttataattc ctaatagggc acgaatagtt gtagatttcc
    96841 cagcaccatt aggaccaata aacccaacca cttcccccga ttttatcgtg aacgaaacgt
    96901 cacgcaatgc ttgaaattta ccaaactttt tttgtaatcc ttgtactttt actatatcgg
    96961 tcataatata gacacactcc tttaaaattt ttttagataa aaatctaaag ctattatatt
    97021 ttcatttcaa tacaccttta atttagtttt atttataaaa gctgtatttc agtaattcgg
    97081 cataaacgtt ccactcttct agatatttct ctccaaatct accaatatca tcaaaggtaa
    97141 acaattcctt tagtcctttc tctcctacac caaacatcgt ccaattcaaa atctcaattg
    97201 ctttttcaat atcaactcct tccctgaatt tagagtaatc aatgtcttta tataatttat
    97261 ttatggcttg attatagatt ggattgagcc tttgtttaat gatatccttt acttctacag
    97321 actcctcttg tttagttgat gccaagaatt caaatgcctg tgggtacttt tgttgaacat
    97381 agaacttttg taaagcaact ctttcgattc ttttaaataa atcagtttca gacaaatcaa
    97441 tttcttcatt tagattcacg attgctttac tactatactc aatcaagtac aagtaaagat
    97501 cctttttact gttaaaatag ttaaacagcg agccttttga aatattagct ctttttacaa
    97561 tttcgttagt agatgctttt tcaaaaccat ttcgaacaaa ttcttttata gctgcgttaa
    97621 taatttgctt ttgtttttct ggttttaagt tattaaattt tgaataaatg atcaaaacca
    97681 cctttcttta taaaccgatg acccaactag tcatttagag tatatcaaaa ttgaccgatc
    97741 cagtcaatat gaaatgaagc aattaaaaat aacatatact taaaaataat attcatttac
    97801 atccatctac ataatatgat aaaaataaaa attcaccttt gttagatagg tattttttaa
    97861 gctttagcat tgctctttac gtaaattcac ctcaaagcct gattatgttt catttgataa
    97921 gataggatgt gagattcctt aaactcttat catctagaat tgataaggaa tcaataattt
    97981 taacaatgaa tttgaacttt gaaagatggg agtaggtttt taaagattct atgcttactg
    98041 gggctatcgt tgatagactt gctcataggg cccatattat ggatatgtct agggagaaaa
    98101 gttatcggat ggaagataca gtagagtggt caaaaaatat atgaaatata tttaaaacac
    98161 ctttccccta ttacgtcatt atacaaccta tatacatata aaaaataaag gcagtccgta
    98221 gactgccgat atttatctct ctgtaccttt gctgtggtct ttcttatttg acttagcttt
    98281 gtcatctgtc ttaaagcttt ttatttgccc taatatggac tttttatctt tatcttgact
    98341 ctttacttgt tcttttgctt ttaaaagctt agaagataaa atacgaacat ttttatgttc
    98401 ctttccgttg ttatcaatgc ttgtttttac ttgaccaaat atctttacaa aatctccttg
    98461 ttttagattc tctatatctt ttgtcttatc tccatatgct gaacaattgg tataaatttt
    98521 attcccatcg tcatcttttg aaacaattga aaaattgctt accttgaatt tttctccatt
    98581 agcattttct ctttcaagat tttctacttt tccagctata ttacccacga gatttataag
    98641 atcgtctttt tcttcaatat cactgacatt ttcaactatc tttccttgtt ctttcatatc
    98701 atcaatcata tagtcaaagt catcacttag taaacctgtt gtgtcattgt tcatatataa
    98761 aacatagact tcttcaagtg ccttttcatc attaatgcct ttttctatgc tcacaattgc
    98821 ttttataaaa tccttgtaat tatcattcat catttcttct aaattttctc taatatcttt
    98881 gtattccata atttcctcct tgtactaaat aaggagagcc tttcgctccc ctctaccttt
    98941 cttgtccttt ttcgtttttt tcttgatttt tatctttttc tccttctgat ttaaattttg
    99001 atatttgtcc caatattgat ggtttctctt cccttgcgtg aagattatcc tctacatcat
    99061 aagttgattc aaagtaatca ctgtctttaa aatcattgtc atacctatct ggtattccat
    99121 cattatcaag atcttttgct agtggatcat agaagtttcc atcatcatct atttctaagc
    99181 ctaaggcttg ttttaaatct tcttcatcta ctgataccag atcatcaaaa cttgacatct
    99241 ttatggcttc agtcatatct ttaatagctt gtgagttaga catatcttct tctacaaaag
    99301 attctgttct aatagctaca tcatctacat actgactcca tgttttttct tccaaattta
    99361 cctcatattg aatagagtgc ttaccatctg gtgtttctgt ataggcaagt cctatatggc
    99421 ttaaatcagg gtatagtttg tcaaagtctt cataactatt agattctgaa aactcgtagt
    99481 tagtataatc aactatcgcc ctttttaaat cttctaatag tggtgattgg ttttctaatt
    99541 cttccacttc tcccatatct aaaagtttat taatttcagc taatcttagt gtcttatccc
    99601 ttaactcatc tgctttttca aatggtttag ttaattctac tttagcattt tctaaagatt
    99661 cttcatagtt ttcaagattt tgatttaatc tttcaagtct tgaaggcatt ttttcaatgg
    99721 cattatcaag ccttgttata ttaccatcag tagagtttga aaactctccg aagtattctg
    99781 cttttcctag aagtttaaag gtgtgattat tagtcataaa gttatatgaa acttgtaagt
    99841 ctaaattcct atatttacca ataaccttgc tatcatttat ctttaccttt tttatttctt
    99901 ctaatagctt ctctccagct tctttcttat ctaaaatttt atttgcacca aggctgattg
    99961 aagtgaattt gctatctcct tctcctaatt tctcaacact tgcaatatct tctttaactg
   100021 cttgtatttc catttcagtt tttaaaatac tttgaggata aattttattt accttgtctt
   100081 caagcttata tttattagac ttgtagtttg cttcaagcat ttttagcttt gtaacttcgt
   100141 tatctaaatc cattttttct ttaattagag gattacccgt agctaaagcc ttaatttctg
   100201 aataagatag acttgcttca tcaacatctt ctgcaactct tactggagtt tttgaagtca
   100261 taatttgaga aatgaatttt tgcttattct ctatcgtctg gtcgagtagg tcggggatat
   100321 tactatccct ttcccctcta agaaccgtgc atgagagttt cccctcacac ggctcaagtt
   100381 tttataagcc ctaattaaag agccagcgta ttttctttat catttatatg caattttcta
   100441 tgacaccaag ggtgtactaa tgttttaagg gtaatattgt tttgagttgt ttgatgtact
   100501 ctaaagtctg tatccagagt tattttctct ccacaaacag ggcatattcc gttttgcgtt
   100561 ttatacagtc tatttataac tgtacgccct ttaagttcgt ttcgtatttt taactcttct
   100621 ctttcttcaa agtatatttg ccaattttca tcaaatggat ttgcttcagc ttgtatcttg
   100681 gtaaatctct taatatcagt atctgtagca tatttaagac gaagatagta tttctcgcca
   100741 ttttccattc tgtctccagt tgctacacta aaagtccaag ttctatttcc aatcgtatgg
   100801 aaatactttt tagctatcca ttttctactt ttcttaggat gtctacgaac acaccagttc
   100861 cacaggcatt tatatatttc ataatcaagt ttttcaaacg cttttgatga aacattatat
   100921 ttctgatagt ttatccaacc tataataatt ggatttaatt ttctaatcag aatttcttgt
   100981 ttcattgacg gattatcctt tatgatttgc cttattttat caacaatagc cttgaagttc
   101041 ttttcggatg gttttgttag taacttatct ttatacatcc taatattaac tccaagaaag
   101101 tcgaaaccgt catttatgtg cgttatgagt gtcttttcct cagacagttc taaccctctt
   101161 tcttctaaaa attttacaat gattggctta acaccatttt caagcaattc cgcactttct
   101221 cctgtaacga taaaatcatc tgcatatctt acaaaattaa cttttgggaa atatgctttc
   101281 ttatttactg ttcttttatg atatttttct ttgattgctt tttctaaccc atccaatacc
   101341 atattagata ttacaggtga tattggtgaa ccttgtgggc ttccagtttc tgtaggaaat
   101401 aatctttgct tttctatata tccgcattca agccaaagtt tcaataacga cttgttcatt
   101461 ggaatattat tcattatcca ttcgtggcta atattatcaa agcaaccttt tatatctccc
   101521 tcaagtaccc attttgcaga tttcttttta ttaagtgatg taaagcactg ctcgatagcg
   101581 tcttgtgtac atctttttgc cctaaatcca taagaattag ggtcagcagt agtttctgct
   101641 atgggttcaa gtgcaaattt atatagtgtt tgcattgccc tatctgtcat tgtgggaatg
   101701 ctgaggggtc ttttcttacc atttttcttt ggtatataca ctcttttaag aggtttaggt
   101761 ttatatcctc ttaaatttaa cttttctatc gccttatact ttgcctgtgg tgttagccat
   101821 aattcgccat ctacaccact tgttttcttg ccttggtttt cagttaccct cttaatagcc
   101881 aaggcttttg cataaaatga agttgtgagt aaatgctgta aagattttac ctttccatat
   101941 ttactcattt tccacgcttt cacaatacgc atttgtagtt ttttaacata gctttctgct
   102001 agagaaaagt ctatactttc ccagttttta gctctgttag tagtagcaca cattttactg
   102061 ttcatttgct ttctcctttc aaaaattcta caagttctct tgtgattaaa aaccaaatgg
   102121 aagtctgcac tctttcaagt tagggcaaat tttgaacccc tatccatctc attacaagat
   102181 ggcattcgct ttttccattc tcctttacct gcaccattat cagcatttct tacgatttgc
   102241 cttgcctttt ggcaatagta caggcttacc atgtttcact taattaacat tgataactta
   102301 ggctctacct ctctgccggt agtctttttg tccgtgtaat cccactgtgg aaaggattat
   102361 ccgactacac accattttgg ttcaggctta tcagcaactt tagcctgttc gccttaacga
   102421 catttatcag tagttcacat atgttagcca tattatcaag cctcgctccc taaccacttt
   102481 gttgctggca gtttcggtat ttcctcacgg ttttacctca agtagggcta ctttaatatc
   102541 ggcttaccac acttaagtgc agtcgatact cggctcaact aacggaatag ttggtttggt
   102601 catcatgcca aacagttaaa ttaagcgact tcatgtcgca cccacaaata cgcatcgaag
   102661 gtattctcag ttacatatct aaatatattt accttatcat tttcattacc ttgacgaaca
   102721 attctaccac ttctttgctc taggtcagat ggtctccaag ggacatctaa atcatgtaag
   102781 gctattagtt tattttgtac atttgtacct gctcccattt tttgtgtaga gcctaataat
   102841 actcttactt ctcctcttct taccttggag aatagttcat ctttttgttt gtctgtatct
   102901 gcttcgtgga taaaggctat ttcttcttta ggtattccca tattcactag cttatttcta
   102961 atatcatcat aaatattaaa ttctccatct ccttttggtg tggacatatc cgaaaatact
   103021 aattgagtcg atgaatcttc ttttgtctta tcccagattg aaaagatatt tttaacacat
   103081 acatttacct ttgaattagg atcatctgga agtaatggat ttattaatct ttggtcaagg
   103141 gcaagttttt taccatcatt tgtaatcttt agcatgttat cttctgttgg ttcgacttgg
   103201 ttgtttctaa ctgcgtctgc tctttctgaa atagcttcta atatttcttt ttgttcctca
   103261 gtaggttttg ttttaataac ttcaaaattt gcttctggca ctggcaaatt taacatatct
   103321 gaagtcttta tatctgctac ttctttaaac atgctcatca gttctggcaa gttatagaac
   103381 tttgaaaatc ttgtcttttg tctataccca gttccttcgg ggtcgagttt gtcaagatac
   103441 tttttgtgga ttttctaaat taaacgattt gtccgtaaag aaatcgccca aaacctcgtg
   103501 cttgcagatg tcttgaaaca ccgtattcaa aggctttttg gcactttcag actgctttac
   103561 atttacgatg aatgttgtct ttccaatgca ttgtgaataa gaatgtttct gttctttcat
   103621 atagtccgtt cctctctttc ataaaatttt gattgatggg tattcacatt agaacaccca
   103681 tcaaccgcag attttcaata tatcaacaag tcattaagtc gtgagtataa tggaaaaggt
   103741 tatctttcca taccacgctt gtttcttcga gccttgatac gctcctgtcg ttctttttcc
   103801 cttgcttctt tttcggctcg ttcctgcgct tccttaaaag aaaaaagttg cttcactttc
   103861 tcggtaaaaa gtttagcaac ttcggggaaa tgctccaacg cttgaagaaa aggtctgcac
   103921 ttttctttca gttcgtcgta tttggttttc attctttcaa gtgcgtttgc actgtcaaaa
   103981 tatttctgtc ggtaatagtt tgcactctgt tctaattcgc tgatttccgc acgactggta
   104041 atgccctctt tagcaagggc agtaagctca gaataatcct ctttggagat tgccatttta
   104101 cccgtgattg ttttctgccc catacggtca atctcgttat aggttttgga aacattacgg
   104161 gcaggctcat actttatctg ttcacgctga atacgcttct gcaacttctc taatcgttcc
   104221 ttgtcctgct tgatttgata ttgtagggaa gtaagatgtt ccgctgtact tccatattcg
   104281 ccacgctgaa agcctttgaa gccttgctcc gtcatatggt taaacaattc atcttgcaga
   104341 atactgtatg aagctcggaa catcggtttt ccgttctttc tgagaagcgg attgcctttt
   104401 tcgtcggtca gcggaatatc cgatttccat ttctttgaat ggctgatttg atgaacaact
   104461 tccttaaccg ttcctcgcag tttttcatct ttgcaacgct tgctccatag gatttctttc
   104521 tccaccacag gcaaaaccat agcgtgaaga tgatagtggt aaacctcttt tccaagttcc
   104581 tcggttgccg ctacattgat ttcatcagcg tgcataacag ccgatatgac attatcagca
   104641 ccgaattttt cctcgataaa atggaatgct tcttcgtaaa actgctttgc atattcgtag
   104701 ccgccgttac gctcgaagta cattgtgttc acatcaatca caatctcatt gaacagcgtt
   104761 gcgtctttcc tcagccctcg aagcgacacc ataccgtcag tttccatctg ctttaattgt
   104821 tccatatagg tcggggcaaa aggctttttg aaatgcacat tatagggtat gcgttcctca
   104881 atcacattca tattttcata ggtttcattc ttgcgttcgt tgtgcctttc tgccttgctc
   104941 acatcagaag cggtgtactt tttaaccctt gcacaactca tatccgcctt gttgtttttc
   105001 gccatttttg ctctcctttc tcggcagggc gaagccatta cacaacattc tttgaatgtg
   105061 tgtaacccac tatgacactt tcagacttcg tctgcaaaga tgtcgtgggc aagggtgttc
   105121 ccccttgacc tcctttgata cctcaatcac aaaaacagac tgtcccaccg acaggcattc
   105181 tgtttttatt ctctcggtat atcgctcatc ggcaaagacc aataccaaag aaaacctttc
   105241 ttcttggaga taactcctgc gtttttcttt gcctttttga tggtcgattt cttgaaccct
   105301 gcggcttcaa gtttttcttc acaatccgaa gaaagcattt ctccgccctg caacatttca
   105361 atgagaaatg attttgcttt catctctttt tcattcggtc tgcctatttg tggggcaaga
   105421 gataaaaacg cttcttcggc tgtcatttcc atttcggaaa tgaagttcac acctttctcg
   105481 gcaacctcaa aaagaattgc cgaacctgtc ggagcaagat ttgatttcac ttgcaccaaa
   105541 tatctttccg caggtgcttc cttgttcggt gtgcgtgtga ttgcaagaat gcttcttgca
   105601 gcacccgcaa tgtcaatcga gccgttggtg cggtagagtg gattattatc tttcatcttg
   105661 ttcatatgag cgataatgac aatcgcacaa cccgtatctt ttgcaaccgc tatcagatgg
   105721 ttaaactccg ctcgtgtttc gttggcatta ttcatagagc aattctctcc gatatacgaa
   105781 ctcaacgggt caagaattag aagctttgca ttgtactttt caatcgcttc acgaatgcgg
   105841 ttatctccga aagataaagt cttttcatct tccttgatga agataagatt ttctccgtct
   105901 ccgccggcag aattgaagcg gggtactacg gtatcgtctg cgtcatcttc cgttgtctga
   105961 tagatgatag tcataggctc attttcttcc gtttcggtaa aggggatagg ttcgcccttt
   106021 gagagcaggg cggcgatgga aagcattaac ttgcttttcc catcgcccgg atctccctgc
   106081 aatagcgtaa ctttgccaaa cggaatatac ggataccaca gccactttac ttctttcggc
   106141 tcgatttcac ttgccttgat gatttcaaga ggtacgctga aattcatttc gttttcattt
   106201 agtttcattt tttcttgttc tccttttctc tgaaaatata aaaaccacag attgatacta
   106261 aaaccttggt tgtgttgctt ttcggggctt aaatcaagga aaaatccttg ttttaagcct
   106321 ttcaaaaaga aacacaaggt ctttgtacta acctgtggtt atgtataaaa ttgtagattt
   106381 tagggtaaca aaaaacaccg tatttctacg atgtttttgc ttaaatactt gtttttagtt
   106441 acagacaaac ctgaagttaa ctatttatca attcctgcaa ttcgtttaca aaacggcaaa
   106501 tgtgaaatcc gtcacatact gcgtgatgaa cttgaattgc caaaggaagt ataattttgt
   106561 tatcttcttt ataatatttc cccatagtaa aaataggaat caaataatca tatcctttct
   106621 gcaaattcag attaaagcca tcgaaggttg accacggtat catagataca ttaaaaatgt
   106681 tttccggagc atttggcttt ccttccattc tatgattgtt tccataccgt tgcgtatcac
   106741 tttcataatc tgctaaaaat gatttaaagt cagacttaca ctcagtccaa aggctggaaa
   106801 atgtttcagt atcattgtga aatattgtat agcttggtat catctcatca tatatcccca
   106861 attcaccatc ttgattgatt gccgtcctaa actctgaatg gcggtttaca atcattgcaa
   106921 tataataaag cattgcagga tatagtttca ttcccttttc ctttatttgt gtgatatcca
   106981 ctttaacggt catgctgtat gtacaaggta cacttgcaaa gtagtggtca aaatactctt
   107041 ttctgttcca actattttta tcaatttttt caaataccat ctaagttccc tctcaaattc
   107101 aagtttatcg ctctaatgaa caaagatatt ataccacatt tttgtgaatt tttcaacttg
   107161 cccacttcga ctgcactccc gacttaataa cttcttgaac acttgccgaa aaagaaaaac
   107221 tgccatcact tgacagcagt tctctttcgg atagtattcc gttatgaata cacaatatcg
   107281 tttaatacga tttcatctac gcaagctctg atattgttca tcaatcctat ccatctcatc
   107341 atatccacag cctttaattg ctcggtaacg ccttgctttc ttgccatttc ctttatgaga
   107401 tattcagcca tatcacaagc cgaagtgtca atctcggcaa ggtgttcata taactttcca
   107461 cttgtcatca gagtgtaata taaaactcgc ttgtgttctt tcaaatatcg ctctcgcatt
   107521 cttccgtacc ttgaaagcaa aggtttttct tctgcggtta agcaggggta gtaatagtcc
   107581 ccgataagtt catatcggat acccgttctt tcgtctgtga taaatctttg cattgcagct
   107641 tctccttttc ttttttatgg tggtaaaatt ccaatgtttt cttattgtga tttacccttt
   107701 gacattcttc ggagcagaat ttctgttggc tgtgtgtagg ccaataggaa ttgccgcaca
   107761 cagcacatac acgctgtcgg taatagtgat ttcctcgttc tgcttctcgg tctgttttct
   107821 ttttgtcttg ccttgcttga tagcagcact ctttggaaca gaacacctgt cggttgcttg
   107881 tcgggataaa ctctttgttg caatgagggc aaacctttgt cttaacgatt tcgccaccgt
   107941 tttcagcgat tttctgtgcc tttcgctttt ctcggtaggc tttttcacgc ttgcgctgtc
   108001 ttgccaagcg ttgctgttcc tcctgctctt tctgtgtttc tatctcggca agttcttctt
   108061 cggtataggc aatatccact tgaccgacat agttaaaata aatatcgacc ttttgtgttc
   108121 gtgcttttcc cacaccctct gcttcataaa ccactatctt atcaacaagt tcattaaaca
   108181 ttgtatcgga gatttccgta ggatttttac acttgcgtat cagcgaaatg aaatgcttaa
   108241 tatcaacgga acttactttt tcttcggcaa gttctgtttt catcgtttcc attttcgttt
   108301 ccaactctgc ctgctcgtca tcatactgtt tcatcagttg cttatactgt ctttcgggca
   108361 gtaatcccga cataagattt tcatacaagc cacgaacaag ggtagagagt tcgtcatagc
   108421 gtttctgaca gcgttgcagt tccgattgat tgtgtttcgg cttttcctcc tgtttttcat
   108481 tccaaagaga ttgcagttcc aaagcaaatg cttgttcatc attcagaaca aaccttgaaa
   108541 agcgtttgac agatgataat atcaaggctt caacattatc ggtactaatc gaatgactgg
   108601 tacaactgtt cactctgctt gcatacccac cgcaacggta agaatactgc acagaaccgt
   108661 cttttttgct gtaatgtgtc tgcaaagtca ttcttcttcc gcaatcggca cagtacaaat
   108721 atccgcttaa acggttgctg tgcgttcccc aagccgaggc acgatttact ctgcttctgc
   108781 gtttttgaac gctgtcccaa agttcctgcg atatgatagg ctcgtgtgta ttcggaaata
   108841 catactgttc ttcttcgtct gtgctttttc tcttgtgaag tttgaaattt gtgcttaccg
   108901 actttcgcaa aacggtgtga ccgagatatt cctgcctgcc taaaatattt cttatcgttg
   108961 acattgccca aagataaggg tttgtgaact tgttgccgtt gtactgttcg gggtggtatt
   109021 cctttgcgta tgccgcaggg gttaaaactt tttcttcggt cagtatttct gcgattgccc
   109081 ttgtactttt gccatcattg gcaagagtaa agatacgctt taccacttcc gaagccacag
   109141 ggtcaaccac aagcgtttgt ttgtcgctcg gcagtcggtt atacccataa gggatagaac
   109201 cgctacaacg ctttccgtct ttcatacggg catcgaatat agccttgatt ttgttgcttg
   109261 tgtctttggc ataccattcg ttcataatat tcaaaaacgg agcaaagtca ttatccgaag
   109321 cgttgttact gtcaatactg ttgttaattg caaggaaacg gacatttttc tgtggaaaca
   109381 gaacttccgt ataaaaacct acttgcagat aatttcgccc caatcggctc atatccttaa
   109441 caatcaaggt ttctacattt cctgcttcaa cttcttttat cagagattga aagccagggc
   109501 gattgaaatt tacacccgaa aatccgtcat cggtaaaatg gcgaatgttc tcaaaaccat
   109561 tcctacgggc ataatcttcg aggtatttct tttgattggt aatagaatta ctctcgccag
   109621 taaggtcatc atctcttgac aaacgctcgt aaagtgctgt aattcttgaa gtccttgaca
   109681 ttttcttatc ctcctttccg tatgtatttt ttcaatttag gacagttaat ttttttgtcc
   109741 tattaaagta tagccctctg gagataattc aaaggtgttt tctgtttctc caaaggtaga
   109801 agcccaagcg tcaaaatgtt ctaatcctct tgcctttaaa tcgtcatatt gaaggtatct
   109861 ttgcatggta taaagctctg tcattgaatt tgatattggt gtaccagtag caaatacaac
   109921 tccctttcca tctgtcattt cgtccatata cctacatttc atatacatat ccgaagactt
   109981 aaaggcttca ctctgaccga tacccgcaac atttctcatc tttgtatgca aaaacaagtt
   110041 tttgtaatta tgagcttcgt ctataaataa cttatctact cctagttctt caaaggttat
   110101 tacatcatct tttttaaagt catcatttag tttttcaagt cttaccaaga gtttcttctt
   110161 tgtcttttcc agttgtttta ctgtgaaatt ttctcctcta tttcttttgt tctcatcaat
   110221 aaaggaaact atatcatcta tttgatcttg tatatgcctt acctggtatt ccttagacat
   110281 tggtattttt tcaaattgag agtgtcctat aataactgca tcatattctc ccgttgcaat
   110341 cctgccaata aatctttttc tatttttagg ttggaagtct tttttatcgg ccaccataat
   110401 atttgctgac ggatataatt gcataaactc cctaccaatt tgagtagtta gatggttagg
   110461 aactacaaat aatgatttac ttgcaagtcc taacttttta gattccatag cagaagctac
   110521 catttcaaaa gtttttcctg ctcctactac atgggcaagt agtgtatttc caccataaag
   110581 agtcctagct attgcatttt tttgatgttc tcgaagtcta atttcagtat tcattccatc
   110641 aaaagttaag ttagaaccat caaattctct atttctaatt gaattgaatt tttcattata
   110701 aatcttctct agcctatatc ttctatcagg atcttcaaat atccaattct taaattcttc
   110761 tttaatcagt tcctgctttt gacttgcaag catagtttct tttttgttta atacagaagt
   110821 cttagaacca tcatcattta ttacttggtc aaataccttt gtatctttta gattaagagc
   110881 attttcaatt agcttatatg catttactct acttgtacca taagtcatgt tagcaaggtc
   110941 attagttgag tcaatacttt taccttcaat gttccattca cttgtatgtg gtgagaacct
   111001 aacatttata ttccacctat cataacctgg tgtttttaaa agattaaaag taaagtcttc
   111061 tatatctttc tgaggtatcc aggttgctcc taatcttaca tttatatcag aagcagtgag
   111121 ttcttcaggc ataacttctt gtaatttttc tctttgatat ttaagtttgc ctaactcgtt
   111181 taataatgtg tctttctttt cataaggtgc taaatctatt acattttcaa tttctccgat
   111241 gtatgaattg aggtaaccaa tcttttctct aatgtttcca cttaaatatt catcagccga
   111301 tacatatgaa aaatgaaatg gatcgtcatt attaaagttt tcaaagggca ttctgttatt
   111361 tattaggtct gtatccttaa tatctaaaaa tatctcgccc tcaagttcac caattaaggt
   111421 ctccctatct ttacttgtga tagattccat atattcaaaa tctacatatc ccttttgtga
   111481 aacagataag actaaagctt caagggaagt atctacatgg tctactactt ttgcctttgt
   111541 tattgttctt tttgagaata tatcactctt agctttgaaa ttatcctcat catcaagtat
   111601 ttctattgat gaaactaaag gaaagtttga gtcttccttt aaggctctag tgtttgataa
   111661 ggagttaata aagccatgtt tctttgtaaa attatcatag acttcgttta actttgcttg
   111721 tgactctttt atttcctcgt ctgaaaaatc atccttttgc ttttctatta catctttcaa
   111781 agcattcatt acatcaagat aatcttttat cttttctttg tttttatctg atatattttg
   111841 ctttattaag actgagtttt ctcttaggta gacctcttca tcaataatgg tgtaagaaaa
   111901 attcttaaca tcatctgttg ctggaagact taattcttca tcttccaata gctcaacctc
   111961 ttcatatttt gaatttgaag atatttcctt acttgcaaga tccattaaat cttttaaatt
   112021 ttcgtcttct ttttcatcac aagtaatggt atttccaaat ctaccagata cttctttcat
   112081 atcccctaaa accatttgag gattatctac aaaatatttg ttgtaggtca gccctttgtt
   112141 atcagttgct agatgaatcc aatcgtcatc tctttctata actgaatctc tcttctttag
   112201 aaaaataata tctgaagtaa cttctgtacc agcaagtcct ttaaatgtag tattaggaag
   112261 cctcatagct cccaaaaact cacatcttgc attaatatat tttctaacag attcatcttt
   112321 tttatccata gttccagatg aagttatgaa ggcaataatt cctccatttc ttaccttatc
   112381 tattgacttt gcaaaaaaat aatcgtggat cagaaaatta tttctgttat attcacgatc
   112441 gttaacttta aaatctccaa agggaacatt tccaattact aaatcaaaga aattgtttga
   112501 gaagtttgtt tcttcaaaac ctttaatttg aatattagct tcaggataaa gttctctggc
   112561 tattcttccg cttaggctat ctttttctac tccatagatt ttagacgctt tcatttcatt
   112621 tggcatatta ccaatgaaat ttccgactcc tgcagatggt tcaaggatat tcccagtctt
   112681 aaaaccaata tctgttagag tcttatatat tccatccatt acctctctag gtgtataaaa
   112741 ggatgttaga gtagactctt tagcattcaa atactcttca tttgttagat tttcttttaa
   112801 aatatttctt gcttcaagcc attgacctcc tttttcttca tcgaagacat cggcaagacc
   112861 accccagcct agatagtcag caagataggc ttgttcatac tcccttggac tcctattttc
   112921 attttcaagt ctttttagca ttttaatagc ttttatattt ttatctagtc tttctgatgg
   112981 tgttaggtat tctgagtaga tatgattttt taagtcgtaa tttctagcaa aacttaactt
   113041 ttccttatta ggttcatagc ctagattctt taaatcttct ttacccctca ataagttttc
   113101 ggctgcttgt cttgggacat catacctatc catcatttgg tcaatttctg gattgtagtt
   113161 atcaataaaa ctttcttgct ctacttgtct ttcaatttga ttttcatgct cagataactt
   113221 gtatatttca taatctccac tatcaaaaag gtcatcaatt tttctacttt cttcaaatgt
   113281 ttcgccttta tataaaggaa tttcatcccc attaatttct actttagttc cagtttcaat
   113341 taagttaatt ctacgaaaag cattctcatc ttctaaaata aattcttttc caacttttac
   113401 tgctattttt tctgatgttt gacttagatt ttcaaagatt tcttcaaggt atgaatcgtt
   113461 tctatatgga attacttccg aacccctaat catacctccc atatattcca tattatctct
   113521 gatggttaca gttttaagtc ctccacttag tgcatcaaaa tctgtaatgg taaagtcctt
   113581 atctttatat ctaacctgat cccctatctt aaatttaggc tctatatttt cctttacttc
   113641 ttcttgtaaa gatttttcct cgcttattgc aacttgttct tctaaatatg aaaattcacg
   113701 ctcatttact tctacaccat caccaaggtc aatcctatag tgttcgacaa cttcgccgtc
   113761 tacatagtgg tcaaaataga atttgaaata tccgatataa tcatcagtca tttctccaaa
   113821 ttcattttct ccatgagttt gattatggtc tttaatatca atatcctttt gtcttaggat
   113881 attgattaag tctttagtta ctatctgccc actataatcg ggaactaatt cgtgattttc
   113941 attaaattct acaatccagt aatcttttct attttcagtg tttttgccat caaaaaaaga
   114001 agcttcatca gcttcctttt ctggacttat ttcattttct aagcttccac gtattccttg
   114061 attgccatct tcttcactgt tgccatcaag ttgttcatct gtccttggta ttcctctgga
   114121 ttccctctca tcattttctc tgtcaatcct tgtgctttca tcatcttgac tttctctctc
   114181 ttgataaagt ccactgcctg attctgaatt tccttcaggt ggttcaaaag tgttttctcc
   114241 tcgtacattt tctgaagttt cttccagttc tccatgtctt cgctccctac caggtaagac
   114301 agtcttagaa ctgcgtatgt tggattcgga aatctctcca taaattccag atccttctcc
   114361 atcatgtcca aggttttctc ttcgatcttc attgctattt cttctgtcgc ttccatctgt
   114421 gaaaactcgt ccatctctac ttcttgacct atcatctcgt ctatataaat catcttgacc
   114481 tcctctatct tcatttatat tttctatatc tctattatag tcgccaccag ccctttctgt
   114541 cagcagccta gctcgatcca tttccttaga tttttctatt gttctatcta taatatcttc
   114601 actaaccctt gatattacaa gacctatctg ctctaaagaa attgtattaa tcctagaaaa
   114661 attatttttt aaattttcca tatccatagg gtaggctgta ttaaacctat tagctaccgc
   114721 ataggatatt gagtccctca taaacttttc aaaactaagt ctatcctcta tatctatcct
   114781 taaatcagca agagccaagt taatatattc atctccataa attcgactca aagaaaatat
   114841 attttcattg agtgaatcac tagcttcaaa tgaagaatta tttattattt cttttaaagc
   114901 ctcgttatgg ttttcgtggt caaattgcca taagctaacc tcattaatat tcctatccat
   114961 tgatgtggtc tgactaatat caaaaatata tgaaactttt ttgtttatat cacttccaac
   115021 taaaattgga atgccctttt gacctctcat aacaactctg ccaaaatatt ttttccacat
   115081 ttcaaaagtc gcacaagctc tagcttcagg ttctttgtta tatatactta gttggctaga
   115141 aaaatcatat ttttgattgt tacctacaac ctttaagagt tttaaatatt ctttttcatc
   115201 ttgtaacact tcatatttta tagcttcttg tatattctta aaatcattta cttgcatttt
   115261 atacctccat tctatgaatt tcttttataa tagccattaa aatatcgacc acaatagaat
   115321 tgccggcctg cttatatagt ttacttgaag tgcaattttt tcttcttgga tgtgcttctt
   115381 ctagtttgtt aatatcactg tcatcaaaac ccattagtct taaacattct ctttctgtta
   115441 aatacctata ctgaccattt ccaatatcta ttattccaga attaggtact ctcatctgtt
   115501 ttgtagaaat agtataagaa aaatctttaa tcacttttag tcgccctcta aaactgttat
   115561 ctataccttt atttaaaaat ttcagcatat aaggttgggt cattgtataa agttcactta
   115621 catccttttc aaaaaattca cttagtggtc ttgtttcttt cctctccaat ttattaaaag
   115681 aaaagttatt tgctccaaga catgaaacaa caaatatcct ctcccttttt tgaggtatcc
   115741 caaagtccat tgcatttaag attttatact tgctttcata tcctaggctc tctagctctt
   115801 ttagataaat aaaaaaggag tccctcatat ttctatcaag gactcccttt acattttccc
   115861 aaattatcca tttaggtttg tctttcattt ctttaattat tctaattgtt tcaaatagta
   115921 agcttgatct agttcctgaa ttctttgctc ctccctgctt ttttcctatt cttgaaaagt
   115981 cttggcaagg acttccatgc ataactaagt ctatcttctc attaggagct ttatatccta
   116041 ctactgattt tgctttataa tcttctccat aaagtgcgtt gtatgattta acacaagcct
   116101 tatctatttc tacataatca acaacttcat aaggtatctt taaattaata aaagcctttc
   116161 taatagcacc tatgccgccg aaaagctcta atatttttac cttattcatt tagattattc
   116221 ttgtacctat ctacaagctc ctttatacta tcttctattt ctcttaaaaa gtcttcttta
   116281 tcaacttcgc cagagctaat ctttgcaagt ttcatttccc attcagatgt tgtttctgct
   116341 gatttaaact tatcctctac aatcgataca agtctattgc ctttttctgt tacaagtaga
   116401 tttttcttat ctcttcttat aagatcctta tggataagat tttcgataat tcctgctctt
   116461 gtagctggtg ttcctaagcc ttttctttct acttctatag ctttatccaa agattctact
   116521 cctgcattct ccatagtctt taaaagtgta tcttcattat aatgacttgg ggctttggtg
   116581 aatttctccg atatattttt agaagttagc ttaattttat ctccagtctt tatatctggt
   116641 aattcatttt tttgtttttc ttttccatag ctctttagat acttggtata accttcatcg
   116701 attatagtct tgccacttgc attgaagtta aatttatcat attcatatct gatttttcta
   116761 ctagattcct ttaagttatc cgaacatgaa gcaagtaatt tatccttaat tagattatag
   116821 attttacttt ctttatcagt taaatctttg gcttttccaa tacctgatat agtaggaata
   116881 attgcatagt ggtctgtaac tttagatgaa ttaaaaatag acttaaagtt tgattcattg
   116941 attttaaaat cttcttcaag tccttccaat aattctttca tagtagtaac catatcatcg
   117001 gttaaatacc tactatctgt tcttgggtat gtgattagct ttttttcata caaagcttgt
   117061 gccaggttta aagtgtcatt tgctgaatat ccaaaatatt tatttgcttc tctttgtaag
   117121 gtcgtgagat cataaggctt atctggtttt gtgcttattt ctttatcttc tacctctgta
   117181 ataactattt catcttctag cagatttaat agttgctctg caacttcaat tctatcaatc
   117241 ctatccgata caagtttcaa tcctttataa gatagatcaa ctgtataata ttttttcttc
   117301 ttaaataggt ttatttcact atccctttta gctattaaat atagggttgg ggtttgtact
   117361 ctaccaacag aatatgtttc cttgtaaatg caagaataaa gcctacttaa attcattcct
   117421 accagccaat ctgcaatagc tcttgcactt gccgatctat ataagtcttc aaagttttcc
   117481 ccttctttaa gatttctaaa gccatcctca atagctttgt tttccattga agatatccaa
   117541 agtcttttaa tcttcttctt acatttagct tgattatata caagtctaaa aataagttct
   117601 ccctctctac cagcatcaca agcatttata actgtgtcga tgttcttatc atttaaaagt
   117661 tttttcaaaa ttccatattg ttttttagtg cttttagata cttcataaat atattcttct
   117721 ggaattattg gaagattttc tattgaccat ttcttccatt tttcatcgtg tctttctgga
   117781 cttgccattt gaattaaatg accgacacac caagaaacaa tgtatccatt cccctcataa
   117841 tatccgtttt ttcttgttct tgatccaatt acttttgcaa ttgtaactgc tacacttggt
   117901 ttttctgcta ttactaactt cattcatacc tccataaatt aaaaaagagc gaaagatttc
   117961 tctctcgctc aagcttttaa aaattattat aatagttcat cttcatcatc ttcatctaaa
   118021 gattcttcat gactttcttc attgtcagac tcatcttctg actcactaat atactcatca
   118081 tcttcttcaa agtcttccaa cattttatct tcttttgctt taactacctt aaaatagtat
   118141 cctgctccta taactcctcc aattacaagt gcaacaatta gaaatgaacc tatcccgctt
   118201 ttcttttctt cttttactgg aacaacagca ggttcttctt tttttacttc ttctttctta
   118261 ggctcttcaa cctttatagt gtttttatct tctgactcaa tcatattaag taggtcttgc
   118321 tctcctactt ctgtcaatag ccttacatta tcttggtttg atgagtgatc cactattagg
   118381 tgcatagttt ttccactttt agtttgaaat gttaagaatt gtcttacatc tactggattt
   118441 tctttatctt tttctgtgtc tccacttggt gtaatatctt ttccattcct atctacgttt
   118501 tcaattactg aacctcttgc cttattttcc tgtgttgcta gactatttac tgcctttgta
   118561 ttaccacctt ttacaagtgg tgttttctta ggaggattat ttgaaggctt ggttgcttca
   118621 cttgtatttc ctggtattct cggaacatct tgataaggaa tctcttcttt tgatggtgta
   118681 aaaacatcat ctttcaacat tttttcaaat tcttcttttt gtggttcata gattgattcg
   118741 ttttgacttt ctatttgccc ttcatttgtc atcgcaaatg tagttgctgg tactgtaaat
   118801 gtaaaaagga gtaacgctat ggctactcct cgtttaatgc tcttattcat ttttctatcc
   118861 tttcttattt tacattttta aatacataga ctgcttttct agcattgtcc cattctattg
   118921 tttggttttt accatcttta atatctccat gacttgctcc gaaagcttta gcaatatttg
   118981 aaattgaagc atgaattctt ccatttataa tcactggctt aacatctgaa ttgtagactt
   119041 ttccatctga atctttcatg acaccagtat caatatttag tcttaatgtc tttttagcta
   119101 agatattatt ctctttattt gagaaaatag cttcacgagt agagttgtca tactcaacat
   119161 taaaacctag agtataagca atatatctta ctggaatcat agttcttcct tggtctacat
   119221 aagtttttac atccatatag actgttgtct taccatcttt gttgataatg ttataaaagt
   119281 ttttatctac ttggaaaact gcaaattctt tttcatcttt aacttgcttt ttgttttgtt
   119341 gttcctcttg ctttttcatc ttgttaagat caaattgatt tagaatgttc ttgtcatcag
   119401 ctttcaaaag ttcatcccac ttcttatctt gagatttctt atcttctttc ttttctttgt
   119461 tttctttttg gagttttaga agttcatcta attttttaga taggtcttga tttagatttt
   119521 tatctttatc atctttagtt tgtttttcaa gttcttcttt cgctttttta tttgcttcct
   119581 cgattaactt ctttgcttct tcaattttct tatctaattc ttcttttaac tttttaattt
   119641 cttcttcata agctttttgt ttttcttcta gtcctttaat tttctcttct aattcttttt
   119701 ttgtattttc agaagattct tttaaactat caatagcctt ttgaagctct tcaattttct
   119761 tacagcattc tgacttagaa ttttctgtct ctttcctttt agactcaagg tcttttatct
   119821 tattatcttt ttcatcaaga gctttttcca aacccttaat tttattatct ttatcctcaa
   119881 tttctttagt cttctttgca agttctcctt ctaaagactc gagcttttct tgcatttctt
   119941 tgactttatt ttcgttttta tcggtctttt ctttctcagc ttctaactcc cattttgtag
   120001 atgaataatc ttcttttagt tttgcatttt catcttgtaa tctttttaat tcatctttaa
   120061 gctgagtaat ttctgctatt agttcatcat tgttagaatt tttgagttcc tcaatttctt
   120121 tattcaattg agcaatctta ttgtctttat ctctaatctc ttcttctaac ttagcctttt
   120181 cttgttttag tttctctcca ttatctttgc aagattctaa ctttgccttt aattcatcta
   120241 tctttgattg gtcttcttgt ttcttatcat ttaagtcttt gatctgattc tctaaatctt
   120301 taatgttttt agttaaatca tcaatcttgt tatctttttc atcaatatct tgtcctgtta
   120361 gatctgtttg agtatcaacg gaatatttat ttggattgta aatagtcatc tttccttgat
   120421 acatatcatt gttataatca aattcaagtt ctacactatc tacattctta tcaaagacaa
   120481 actctccatt ttcaaacctt aatccattag gaatagattt gaacccttga tttccgttga
   120541 aaccaaaatg attttcgtaa aatggatttt gttttggtct atattcaaca tcttgattat
   120601 ggaaaactcc cttactgtta atatttggat tacctaaaac ttttatagtg tgcaatttat
   120661 ttcttgaaaa agcatactgt tcaattgtct tcacagactt cggtataatt atttcttgga
   120721 ggttatttct ttcaaaagca ttatgttcaa tatttaccaa agtatcaggt aaagtcactt
   120781 ctctaagtcc acaattgaaa aatgctaaac caccaagata agttaagcta tttgatagtt
   120841 ttacctgatc tatacttgct tcgtaaaagg cagcataacc taaatgctta acagaatcag
   120901 gaataattac tttatcccaa tgtttgccac gtccaaattc tcttttatat ctaagttcat
   120961 cgtttgaatg acttaaagaa taatttccat ttatagactt cgttccttca ggaaatacta
   121021 gaatatttgt cttctctttc ttttctaagc ctttatcact aaaggcaatt atatttccct
   121081 cagaggaata cataaaatca tcttccgtcc aagtaacatc agactttgca aatgcacttg
   121141 tatgcacagt tgatgttaaa actaataaaa gagccataaa aaaggctctt agtctgttcg
   121201 tattaaattt cttcattatg aatgttctcc ttttctttta atttttcttc tctttttcta
   121261 tcattgattt tctccattaa ttcttccaag ctaatattgt tcctcctaag agttacaatt
   121321 atttcttcat tttcaacttg tatttcttca tcgcaaattt ccttgtattt tgcatttaaa
   121381 tcttttaatt tctcttctat ttttttcttt ttgttcctaa tacttataag ttttctgttc
   121441 acataatatc tcccttctat cttggtcttc caaaaccata aaaatgtgat ttccaatatt
   121501 ttgaatttat tgacgtgtat tgaattggat ctcctgcgtg aatcatcatt ccgttacctg
   121561 cgtatattcc tacgtgagat attggtgttc cactgttata tgttgagtgg aaaaatataa
   121621 tatccccagg ttgggcttca cttggactta ctggattaca atagtctttg tatatcctcc
   121681 atgcagttgt tcttggcatt ctctttacac cagacttagt aaatgaccaa catacaaaac
   121741 ctgaacagtc aaagttagat ggtccacttg ctccaaacac atatcttttg cctatatgtt
   121801 tttctgcttc attaaaaaga gccttggcag tagcggaatc aaaagcaaga ccaggatttc
   121861 caaagtttgg attgtctact atttctccta agtcccaatt acctgatcca aaaacatctc
   121921 ccatatttcc cttagcttca agaagagctt cataatgaac tacattgtct ggataatctt
   121981 taaatatttc cctaacaact tcatccattt cttttttctt taaagttaca attaactttt
   122041 tatattcgta ctcttctttt tcatagctag tataaggatt gccacgacta tcatatctag
   122101 ttcttgctac tgttcttgtt ctaatttcaa tttcttcttt aaaatcaagc ttatacattt
   122161 tatcgaaaag atcttttaaa attcctttta cttcagatgc tgattttact tctccacatc
   122221 ttgaagttat ataggataaa agttcatggg tattatgacc aatttctcct tctttgttta
   122281 taatatattc gtcatatcca ggatgacttg tttttacact ttcgatttgt gattgtaggt
   122341 catattccat tgatgaaaat tcttgattta cttcacttag aattgtgtct tgtgataggt
   122401 atgttgttgt cattactgag ttaacagagt tacttaatcc actcatacca acacttccac
   122461 caccaatcat gattgatagc ataagaccta gccctattac tagaaataga accatcttac
   122521 tttttcttac gattagctct ttagaagcct tacctaaact taaaatagct tttttaactc
   122581 tatctacaag tcttgtttcg tgctttttag ctatcatgct cttcatttgt tttctctggt
   122641 aaaacttctt aaatctattt ttctttatat atgattctga cttttttaaa tcttccaagc
   122701 cacttttaaa ttccaacttg ctttttctct ttcttatttt cttatcaagt ttagatagct
   122761 tttttaagga ctttttcttt ttgtctaact tatacttcct tattccatgc tggagtttag
   122821 agcttacatt agcggccttt tctccagatt ctacaccagt attatcagat cctgaactta
   122881 aataatctct cactaattct gaagacttag ctccagataa taaaacccca gaagatagac
   122941 ttcctttagt tttattcttt aaaatattat cctttagctt gcttttagac ttttcaagct
   123001 ctccaatctt tttatctgag ataaagtctt taacatcttg tgccttctta gaatcttttc
   123061 ttgtaacttt cttagattca ttttttaagt catcgatttt ctttcgagtg aatttatcac
   123121 tttcataatt ttttctctta tagtaagtct tctttttatt aactttcttt tgttctgaag
   123181 gtttaaggct tgtttccttt tcatctttta taaattcttt attattgtct ttaagctcag
   123241 aattgtcaaa agtcttatct gtatcaactt cgcttagctt attttcttta tctatctctt
   123301 tagaaatttt ttccttatct ctaaacttct tttcttgata aagcttctgc ttttgctttt
   123361 tattgatatt agtattactc tcgttcttgc ttacttcatc tttaacaagc ttatcttttc
   123421 tgtatattct cttacttttc tttgcttcga taggtttatc ttcacttgta tgaattcgct
   123481 tagactcttt ctcgttgatt ttgtcttgga atttatcctt actatggata agtttatcct
   123541 cgtaattttt gagaacttgt cttttacttg atgccttctt attgcttatt ggttgagcct
   123601 tagctgaaat atcatctgtt gttagtttat tagaattaat atttctactg ttttcactat
   123661 caaaatttac ctttttaaaa tctacatcta agtcttcatc aagtttaaag ctttcatctg
   123721 tcctcatttc aagattagtt tgttttgttt ctccagcctt atccttatta tctaaaactt
   123781 cttttctgat tctttccttg tttttagcct tctgaaaatc ttttagttta tcttgttttt
   123841 gatctttagc taatacattc tcatgaataa gtttagattc tttttctgaa attttatctc
   123901 cgaacctatc cttagtttta attatcttat tggtataatc atctgaatga acaagtttac
   123961 tatcaatatt cttttcagga gcgtccctat ttcgtataat tttcttttga aaatcttttt
   124021 ttagtttttt atccatatca cacctactta gcttcttctg gttttgttgt cattagctta
   124081 tatagcatgg tgtctttagg gaatttatca ataaatggaa caatagtatt tccgaagaat
   124141 aagagtccct cacctgcgtt tgaattagtt atataattaa gctgataagg cgatattttt
   124201 aatttcttag caagaatatc tctatctcca gatgcttgat ttaacattag aacaaagtct
   124261 gtattgtcaa agatattttc tatttcctga cttgttaaaa ggtcttttac gttttgagtt
   124321 atacctgttg gaataccacc ccattttcta aatcttttcc agatttctac tgaatatgaa
   124381 gcagtttgtg ggtcttttaa taaaaggtgg aactcatcta tatagtatct tgtagacttg
   124441 tttcctctat taagggaaac cttgttccaa acttggtctt gaattacaag catacctatt
   124501 tttttaagtt gtgttcccag ctcttttata tcaaagcaaa gaagttgcct atttaggtca
   124561 acatttgacc tattattaaa tacattaaga cttcccttaa cataaatttc catttctgtt
   124621 gctagttttc taccaactcc ctcttcttga gataagagca tatagtataa atctcctaat
   124681 ataggcatat tttctggttt tgggtcttca aaatattttt gatatatctt tggtaagcac
   124741 ctatctataa cagatttttc tgcagcagta agaccagatc ctcctactac aagttcaagc
   124801 atagacatta tgaagtttgc cttatccttt aaaggtgcgt ccccatctcc atagttcata
   124861 ttaatatcta gtggatttag atagtccttt gactttgctg aaactttaat aacttctcca
   124921 ttaaattgtt ttacaaggtt tgaatactcg ccttcaggat cacaaataat tacatcgtca
   124981 tctgttacaa gaattgcatt tgccatctct ctctttgccg agaaagattt accagaacct
   125041 ggtgttccta atattaatcc gttagggttc ttaagtttct tcctatctgc cataatcaag
   125101 ttttggctaa gggcatttaa tccatagtac aaagaatttg ccgaatcaat aaatagctct
   125161 tctgttgtaa aaggcataaa tactgctgtt gatgatgaag ttaaaaatct ttttatctcg
   125221 acttggttaa ctcctaaagg taagacagaa acaagtcctt gctcttgttg gtgagataat
   125281 ctttttacct gacaattatg tctgtttgca attgatgaaa tttgagcaat tgtattttct
   125341 aatttttgat tagttctagc aaaattcatc attacaatgg taactacaaa gagcctctca
   125401 tctctatttt gtaagtcaga taacatggac ttaacatcag ccccaaaagt atttatatct
   125461 gaaggaataa tatccatatc atatccagca cgaactgctt tcttttgttc ttcaattttc
   125521 attctgtcca gatctgtgtt ttttctctta atgagtttaa tagcttctgc ttgttcaact
   125581 acatctatat gaaaagctac ataaatattg tcatcaatat ctaaaaactc agataacatt
   125641 ctgtctgata actcacttgc aagtatttga aaatgactta ctgctccaat gaatttgcca
   125701 aatttaaaat tatttgctgg tgcaaaatta aagatattgg gagttatatg tgattttgta
   125761 gactctttct tcttcaaatc tttatatgaa aaatcaaagt tcttgtctgg atttaacata
   125821 tcgtgaacaa gtcttagtct ttcttcgcca tcaaggctct ctgctcttac tcccatagat
   125881 ttaaagttag ataaaatatc tacttcaagt ctatttaact tcgctcttgc ttgctctagg
   125941 ttgtcggctt ctgttgtaaa ggttatatac ttcatctttt taagtccgtt attgcccttt
   126001 gcaagttgaa gctttaacat ctccctaaac tcttttctta catcatcata gaagtctccc
   126061 ttatcagcaa ttttaattgc atcttgtagt tctctattcc ttcctaattg atttacatat
   126121 gaaagttcaa tgtggacact tggatcaaaa gaatttaaaa agttggcaaa ttggttaaag
   126181 attaaatctc tatcttcttc caatgccaac tggtaattta tatcttgaaa tgaaattgtc
   126241 tttgaataat ttttttcatc taactggcat atgccctctg gtaacattct tatataggga
   126301 atagtatcct caacagtaaa tctctttttc tctttcttta aaattacact tagaagacta
   126361 tttgttggat ctttctttgt ttttagcctt cttacttcct ttcggtcttt ttttaattgt
   126421 ttttccctta gatttaagtc gctgatttgc ttttttcttt gcttcaaggt atgcctcctt
   126481 tcttattctc ttagttggtt gataaaattt atgaagatag aaaaatttaa aatatttttc
   126541 aaaagttaag gtatcttttt catataaggt tataaaaaag attggcaggg ttactattag
   126601 cattacaatg attgaaacat cattaggtag atatttcttc ataaataaat aggttggtat
   126661 gccaattact cctgccacag aaaaacctat aagttgtctt ttggttaagt taaaggcaac
   126721 ctttgtttta atcttatcca aatcttttgg tattggtaca tacgccattt taatctccct
   126781 ctacttcttt tttggaaagt tcaagtatat ggtcataatt agatgttgtt tcttcttcta
   126841 ggtagctaat tctttcttct aattcttctt gtttttcttc atttctgtca ttgtattctc
   126901 cttgatacat aacaaattca ttgtgacatc ttccgagtct gtttattctc ctctttaaat
   126961 ttctaatctc ttcatttctt tttttctctt ttaagatttc ataagttcct cccaataaaa
   127021 ttccaagtcc caataaagca caatttttct tttttaacat ttattcctcc tagtgcgtat
   127081 tcataatact ttttgcaact gttccactct taaacatcat aagtccaagt agtagagcat
   127141 atcctaatat actaaacaag cttgcgtgaa tatctgtaac ctgtaccgtc cttattaaaa
   127201 cggtgtagat acctaaacat accatcaaaa acaaaccttg tagtcccaag gcaaaaagtc
   127261 ccttgatata atttgttcca atctgacccc attctttatt tcccatagtc gcaaatggta
   127321 tggatgatac tgatgagtag acatatattt caaacatacg cccatatact attaaggtaa
   127381 tagttaaaga tatacattga attgcaatcc ttacaaggct tgtttcaact aatatcatta
   127441 ttaatgcacc aacatctttt tcttttaatg tatcaaccat tgcaactatc tgatctcctg
   127501 aaacagtggc agaagtagtg attacccctg ccgctttgtt tacaagattt tgtgccacat
   127561 caaagactgc cattgaaaat tcaaaggcat ggcttgcaag gtagactgct ataaacatct
   127621 ttataatata tttgaaaaac tcaaaagtat ctgtatcatg catattattc ttttgcataa
   127681 ccatatttat gagttcaata cataatactg ctgttatgat aagacctgct attggaacga
   127741 tcacattatc attaattttt tttatgaagt tatacacttc tccattccaa cccattggtg
   127801 ttttcccaac atcagttgca ataactccta ccttgtcatt tatatctaag aacatggact
   127861 caagatttgc tttgatacct ccgagtagca tatccttaaa aaattctgtt agcttgtcaa
   127921 agataccaaa catagacttt ctcctatttt aaagcatttg caagtagtgg aattaatttg
   127981 ataccgatta gcacaattcc tccaccagcc ataagctgct taataccttg
//
LOCUS       DAMJXI010000005       127499 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.005, whole genome shotgun sequence.
ACCESSION   DAMJXI010000005 DAMJXI010000000
VERSION     DAMJXI010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 127499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 127499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..127499
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.005"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            247..2901
                     /gene="adhE"
                     /locus_tag="PC465_000542"
                     /gene_synonym="adhC"
     CDS             247..2901
                     /gene="adhE"
                     /locus_tag="PC465_000542"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDF2647873.1"
                     /translation="MAHKEQVIIENKKENEVMSVGLDTVNNVESLVKKLAKIREAQKI
                     FATYSQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAY
                     KETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSP
                     HPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGM
                     VKSAYSSGKPAIGVGAGNTPAIIDDSADIKTAVNSILVSKTFDNGMICASEQSVIVLE
                     NIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPV
                     DTKVLIGEVESVEIEEAFAHEKLSPVLAMYKASDFDDAVRKAEKLVEDGGFGHTSSLY
                     IDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVS
                     ENVGVKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVALKELKDVMNKKRAFIVTD
                     TFLYNNGYTKAVTDLLDEMNIKHTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGG
                     GSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKMGEKANFVAIPTSAGTGS
                     EVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEA
                     YVSMLATDYTNGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFL
                     GVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDAPKKMGAFSQYKYPEALKRYAE
                     IASFLGLKGNSDEEKFQSLLVAIEDLKLKVGIPKSIKEFGVEESKFMDSIDEMVIQAF
                     DDQCTGANPRYPLMNEIKDMYLNSYYGR"
     gene            3177..5396
                     /locus_tag="PC465_000543"
     CDS             3177..5396
                     /locus_tag="PC465_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2647874.1"
                     /translation="MTGRNKSFTLITILFLTSLFLTMGYIYIEDTKHLLMSEAKIHIK
                     EVAVQGSQLAQRQIEKDLDVLNIFSNYYASNPDIPNEEKMKNLLDEMENQKFYTMAIV
                     DINGNAENTKGDKFSVKDREFFKNSIKGKKYVSSPYVDEVNKSIKKIAISVPLLNNDK
                     VVGVLYCTYNINTLMKLINISFYENNSISYVVKNNGTIILHPQGDSLSKNIYKLLKQD
                     NDIQEVNRLKKELQENKTGATVLNMLEERRYLGYATMDNGNSENNYIKDWNLIFSIPE
                     TVVFSNSKQIINRAVYAVLSIVLIFIAIIFYIIYIKKSNEKEILSLAYEDKVTYIGNQ
                     NKFYRECSKYLLDKPSLNYIIVYFDINNFKMINDTFGYEFGDNLLITIAKALKEELTE
                     GEVYARLSSDYFAIFCDYKNGRNKIIRKLDNIRSNIESNLSIVFEISLCVGIYFVEEG
                     EVDIQKAVNKANMARSVAKGKNINYAIYNEDVRNKLSEESMILDDIKIALVKNQFEVY
                     YQPKFSLVTGEMIGSEALIRWNHPEHGFISPAVFIPIAEKSKLILKIGRFVFERVCND
                     LYEWKKQGKKIVPVSVNLSRVELYQPDIVKFINKTIKMYNLSSDFIEIEITETVAINE
                     LNILKNVLNELRTYGFSISMDDFGTGYSSISCLRDMPIDILKLDKSFLGGIEHDERSR
                     NIAKSIVSLAKSLDLVVIIEGVESKEQAELMKQFGCDLVQGFYFARPMPAKNFLDLL"
     gene            5650..6312
                     /locus_tag="PC465_000544"
     CDS             5650..6312
                     /locus_tag="PC465_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HDF2647875.1"
                     /translation="MIDISIDDKLKERWPNAKLGCIQAKVAVNKSSEKLINEINEFCD
                     TINQSLKVEDITKLDKIKDARNAYKELGKNPSRYRTSSEALVRRIIQGKGLYTINNIV
                     EINNLISIKSLYPVGTYNVSKLHSPVCFTVGDEGEQYKGIGKELINIENLPILSDSVG
                     KFGSPTSDSERAMITEDANEILICIFSFSQESDIEEYFGYAKELLKEYADGKDIETKI
                     IK"
     gene            6683..8092
                     /locus_tag="PC465_000545"
     CDS             6683..8092
                     /locus_tag="PC465_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HDF2647876.1"
                     /translation="MIDGKEVKQESGQKNLKFKIAIVVGVLFVAYIGMAIFFRNHFYF
                     GTTINGVKASGKTVEQVNDLLASSTNSYTLNLEERNNKKEQIKAKDIDLKFTPDDKVQ
                     KIKDSQSAIGWIGGIFKSKEYNNMITLSYNKDLLEKRFNALSCFDSKNVVEPKSAYPK
                     YDSTKNAYVIVPEVLGNKVKKDDFYKLVQNSINSGNTSISLDESKVYEAPNNTKDSEK
                     LKQAIKTLDKYVGVVVTYDFSDRKETLDGSEINKWLKVDSEKNYDITFDNDAMVEYTR
                     GLSKKYSTFGDSRPFKTATGKDITISGGIYGWLIDKKKEAEALVDVVKAGKNVTREPI
                     YIQKAVSRNKDDIGNTYVEISLSGQHMWFFKNGEMLVSTDVVTGDLARGFATPSGIYP
                     LNYKARNVSLTGQGYSSPVSYWLPFNGNIGIHDATWRNSFGGSIYKSSGSHGCVNTPF
                     SKAKKIYENIEPGTPIILY"
     gene            8207..8482
                     /locus_tag="PC465_000546"
     CDS             8207..8482
                     /locus_tag="PC465_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif11-like leader peptide family natural product
                     precursor"
                     /protein_id="HDF2647877.1"
                     /translation="MNEKLTKILEEAKNDDEFRKELIKTREQRDVMDSFCKVVTSRGY
                     DMTVGELFSMGEEYTSNLLKSVNGGAAYPIEDWSDWYEDFFIMLSNI"
     gene            9112..9423
                     /locus_tag="PC465_000547"
     CDS             9112..9423
                     /locus_tag="PC465_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647878.1"
                     /translation="MAFEIIKSIVEAEQTADSIKVKAVTDAESIRADAVNKCESIFAD
                     VKKQAKLMEETLIEKAVTDSRAEVDKILANAKSECLKIEKTAEERKSKAIEAVIGKVV
                     R"
     gene            9425..11350
                     /locus_tag="PC465_000548"
     CDS             9425..11350
                     /locus_tag="PC465_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HDF2647879.1"
                     /translation="MAIVNMNKISIVGLEAQKSQILKLLMNRGFVQIDDSAFLTEEEE
                     LKNYLVKDSEESEVIMLEQKMSHVNQAINIVSSLVKQKKSLLAPKREFNKIDSEKEGQ
                     VYAEALELNNLHKEIGTIRSNINLLNNNKSMLEPWVNFDIPIENMETKYTKTILGTVP
                     ISANIDALRVKLEDEIPESVIGIVNSDKLMNYVYLITLKETFDDVLEVLKEFNFSVVS
                     LPNEEGTPLQAIKKYNEMIIRQENVSKDKTEEIKRHADSIHMLENLYDFYTIERDQKK
                     IIERLVKTKTTFCLNGWLPSKRADELIKEITEKFDCCVQTEEGSKEEGFPILLENNKL
                     VTPFESVTNMYSYPSTKDIDPNTILTFFFVVFFGMMLSDAAYGLIIAVVCGFVVYKLK
                     IQKGEGNLIKLIGICGVSTTVWGLIFGGILGDLIPIKALINPLEDVMTLMGMSLLFGI
                     IHIYVGLGIKAYTLIRSGKVIDAIFDIGFWYLCITGVCLLIIPFVAGDIGVFSEVGKY
                     LAIIGAIGLVLTQGRSFKGIPVKLFKGFSSLYGITSYFADILSYTRIMALCLTTGVIA
                     QVINLLGAIAGPILAVVIGVVGHTINLLINALGAYVHTSRLQYVEFFNKFYEGGGVPF
                     VPFKYKTKYTSINKKEM"
     gene            11353..11844
                     /locus_tag="PC465_000549"
     CDS             11353..11844
                     /locus_tag="PC465_000549"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HDF2647880.1"
                     /translation="MEFLNALGNGQFLAISGAAIAALFAGMGSAKGTSIAGQAAAGVV
                     TEDPSKFGQLLVLQLLPGTQGLYGFIIAFLILSKAGIIGGDAIPTSAQGLQLLMAGLP
                     IGLVGLVSGIAQGKAAAAGVGIVAKRPEELGKAITFAAIVETYALLGLLVSFLAYNGI
                     AIG"
     gene            11896..12459
                     /locus_tag="PC465_000550"
     CDS             11896..12459
                     /locus_tag="PC465_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HDF2647881.1"
                     /translation="MGNEQKMIDRIIADAKQEAQEILDKAKSEADLKVNSANEKAEKE
                     MASYTKLAEAEAEKAASKEISGAYMEAKKQILSKKQEILEEVILEAKNKLLNLKDNEY
                     EEIILNMIEKSNCTDDSEIVLSKKDKKTLKDVLSKKGIKVSDETRDITGGFIVKKGDI
                     EYNYSFEAIIAVEHEYIEQIAAEILFN"
     gene            12474..13451
                     /locus_tag="PC465_000551"
     CDS             12474..13451
                     /locus_tag="PC465_000551"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit C"
                     /protein_id="HDF2647882.1"
                     /translation="MAEEKTYPYAVARIRVLEKQLLNRQMFIQMAEAKSPEDSLRIIA
                     EAGYADTSNNNIHNFENILTQELSKTYEILKSLAPEEKFVDVFLYKNDYHNLKVLIKE
                     EISGVDGEKYLIDGGTIPLIKLRESLANRSFSDLPKIMSSAILEAFDVYNKTQNGQMV
                     DIVLDKATFTSMKETAKESQNKFVIDYVMKVCDLTNLKSFIRVKNMKKDFDMFMNVFV
                     SGGSLDKEKFLEAFSSDTPASCFKSTSYSDVCKNGMDSGFTVFEKLCDDYLMEYVRGA
                     KFKPLTLEPLIAYLYAKESEIKTIRIILTSKLNNIDADTIKERLRDAYV"
     gene            13438..13761
                     /locus_tag="PC465_000552"
     CDS             13438..13761
                     /locus_tag="PC465_000552"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HDF2647883.1"
                     /translation="MLMYKVGVVGDKDSIMGFLALGIDIFPAYDSDEIKKSIHKLVED
                     EYAIIYITEQASLLAKESIAKYKDYQLPAIIVIPGIGGSMGLGMNEVRESSKRAIGAD
                     ILFKE"
     gene            13878..15656
                     /locus_tag="PC465_000553"
     CDS             13878..15656
                     /locus_tag="PC465_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HDF2647884.1"
                     /translation="MKTGTIVKVSGPLVVAEGMRDANMFDVVRVSDKHLIGEIIEMHG
                     DKASIQVYEETSGLGPGEEVVSLGMPMSVELGPGLISTIYDGIQRPLEKMYDISGTNI
                     TKGVEVSSLDRTTKWEFKPKKSVGDKVVAGDIIGGVQETAVVECKIMVPYGVKGTIKE
                     IYSGEFTVEDTVCVITDEKGNDIPVTMMQKWPVRKERPYREKKTPDSLLVTGQRVIDT
                     FFPITKGGVAAIPGPFGSGKTVTQHQLAKWADADIVVYIGCGERGNEMTDVLLEFPEL
                     KDPRTGESLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRW
                     AEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGKVNCLGMDEREGTLTAIGAVSP
                     PGGDTSEPVSQATLRIVKVFWGLDASLAYKRHFPAINWLTSYSLYQEKVDVWADKNVN
                     DNFSAQRAQAMKLLQVESELQEIVQLVGVDSLSDGDRLILEVTRSIREDFLHQNSFHE
                     VDTYTSLHKQYRMMGLILKFYKSAQDAIKQNVTINDIIKLSVLEKIGRAKYVEEGDID
                     AAYDSIEDEIDNELADLIKKRGAEEL"
     gene            15653..17026
                     /locus_tag="PC465_000554"
     CDS             15653..17026
                     /locus_tag="PC465_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HDF2647885.1"
                     /translation="MIKEYKSIQEVAGPLMLINGVEGVKFDELGEIELSNGEIRRCKV
                     LEVNGDTALVQLFESSTGINLAESKVRFLGKSLDFGVSPDILGRVFSGMGRPIDGGPE
                     IIPDKRLDINGAPINPAARDYPAEFIQTGVSAIDGLNTLVRGQKLPIFSGSGLPHANL
                     AVQIARQAKVRGTDSKFAVVFAAVGITFEDAEFFISDFKATGAIDRSVVFVNLANDPA
                     VERVSTPRMALTAAEYLAFEQDMHVLVIITDITNYAEALREVSAAKKEVPGRRGYPGY
                     LYTDLATMYERAGKMKGHEGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRELY
                     KKDIQPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFAAYSRGKDAKELMAILGES
                     ALSEIDLMYAKFADEFEKEYVSQGFRTDRTIEQTLEIGWKLLSMLPKSELKRIRDEYF
                     EKYMPKE"
     gene            17032..17700
                     /locus_tag="PC465_000555"
     CDS             17032..17700
                     /locus_tag="PC465_000555"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HDF2647886.1"
                     /translation="MARLNINPTRMEMTRLKKLLKTATRGHKLLKDKLDELMKQFLEI
                     VRENKRLREEAENALDTAYKNFIIARAVMSQEYLGSALMMPKQSVSVDVSTRNIMSVD
                     VPVFDFKTENNQSDIYPYGLAFTSGELDSAMEAFSDAMQPLLRLAESEKSAQLLAQEI
                     EKTRRRVNALENVMIPNYIETIKYIAMKLEENERASTTRLMKVKDMVLKKALEEKKKN
                     DLVV"
     gene            17977..19026
                     /locus_tag="PC465_000556"
     CDS             17977..19026
                     /locus_tag="PC465_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2647887.1"
                     /translation="MKEFIFTCLCIVVITFMTSCISTTPQTTQGKGNNKLTIYAALEE
                     EQIAYYMEGFREEYPNIDVEIVMDSHGVIASKLLAEKDNPQADIIWGLSAMNMIELKK
                     DGALEAYKPKNYDKVDKKFKDTEDDVSWVGMSVPETAIVVNYKELKKLGIDIPKSYED
                     LIKPEYKGLITMPNPASSGTGYLTVSGLIQMMGEKDAYNYMDKLHKNIATYTHSGSKP
                     AKLAGSGEYPIGITLGYRATQQLSSGEPIEVVFPKEGSGWDLEANALVKKDNIKKEAK
                     LFLDWAISDSAMDRYAHEVAVTSIKTDNPVPKGYSKQPFEQLIKEVDLNSAAKNRSTV
                     LKTWESKYGSKSESK"
     gene            19122..20111
                     /locus_tag="PC465_000557"
     CDS             19122..20111
                     /locus_tag="PC465_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2647888.1"
                     /translation="MSYLKINNVFKSYDQKKVLNNISLDIEEGEFLCLLGPSGCGKTT
                     LLRIIAGLEDVNSGTIILQDKDITNLEPSKRGFGIVFQSYALFPNMTAYNNIAFPLKE
                     RKVSKEKIDNKVKEVLETVGLTNEAHKYPKALSGGQQQRIAIARALALEPKFLLLDEP
                     MSALDAKVRHKLRMDIKRLQKELNITTIMVTHDQEEAITMADKIAILNGGDIMQIGTP
                     EEIYQNPQNLFTAQFIGDTNCFDNGDSILTVRPEYVQIEKSTKENYQGIISNIEFRGN
                     LLRVEIKDKLNENFIISDVSIKEWVNLNLVEGDLVKISIDEKYYLKYPKVKGA"
     gene            20116..21834
                     /locus_tag="PC465_000558"
     CDS             20116..21834
                     /locus_tag="PC465_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HDF2647889.1"
                     /translation="MNNNAISSKSISLKSKMNLDIKKCMLTVLVMSLVIFLLAPIIYL
                     FVQAFLDKDGVFVGLQNFQEYLASESLLNSLKNTVFVSVISTVISLTLALVYAYALTR
                     TKIKFKGFFKSLAMFPMFAPTMMHAIGLVYLFGNQGLVTNLLGVHVPIYGAVGIILAQ
                     IIYVFPQSFQILYISLSSTDYRLYEASNTMGISKIREFISITIPSIKYSLISSAFVSF
                     TLCFTDFGAPKVIGGEFNVLSIDVYKQIIGQQNMPMGATVSILLLIPAIISFIVTKKI
                     EKNQNSYITSKSIPYKVKTNKLRDSILGGVVGIIAFGIIAVMLTVILSSLISVWPYDL
                     RLTLEHFSMKNSIDGIKPFINSIKMSLFTAILGTSFVFLFAYLNEKTEKAPYLKSFGY
                     FLSTLPMALPGLVLGIAYVLFFNKLEFNFMDTIYIKNLFNGLYGTLLIMVICNIVHFF
                     SVAFITATTAIKKVDKELDMVAKSMGINSASILKNVTIPLCLPAVLENFMYFFLNSMV
                     TISALVFIYTASSKVAAISIVQLDDKGSTAQAAALAVLILVTNILVKVIYEFIKNRLE
                     KRTNFN"
     gene            complement(21916..23070)
                     /locus_tag="PC465_000559"
     CDS             complement(21916..23070)
                     /locus_tag="PC465_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2647890.1"
                     /translation="MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYS
                     LSERSKHIYEYVERNIDKNTFTEINSKEDQSKKSYKSSKILLESVKNTTGVMYLYTAK
                     KTKDGSLVYVVDGLNSSRSDFRNAGDLIEKEIWGDLNKALDNHILLPKKIKSTSWGYI
                     FISYFPIHNDVGKVVGVIGIEFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFK
                     RISNPTYTDFANTDYLTGLKNRNAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKF
                     GHQTGDLYIKQASKIIQYVINKKYIVYRIGGDEYIIILKNLSHKEINNIINNINLKIV
                     EENSTNELKLSMSIGYAIFDEKVDVSLFDTYRRADSQMYDNKRKINKQYQ"
     gene            23569..24930
                     /locus_tag="PC465_000560"
     CDS             23569..24930
                     /locus_tag="PC465_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2647891.1"
                     /translation="MKDRLNLTEGRITEKLLKLSLPIMGTSFIQMGYNMIDMIWVGKA
                     GSKAVAAVGTAGFFPWLAMAFIMISKVGGEIKVAQSIGANNISTTKSYMKSAIEINII
                     LAIIYTISLIVLNKQLIGFFRLGDLEVITMSRQYLIIVALGMVFYFINPVFTAIFNGL
                     GNSKTPFRINTVGLITNIILDPILIFGWGFAPKLGVAGAAIATVFAQIVVTTCFIYII
                     VKSKEEYFKLRLFKEIETKYYKVLYKLGLPIAIQSGMFTVFSMLLGVIVASWGPVAVA
                     VQKVGSQIEAISWMTAEGLSVALGSFVGQNYGAKKYSRINKGCKIAITVSSVLGIITT
                     LVLVFAGESIFSIFIDESEAIEKGAVYLKILGYSQFFMCLEIITTGAFKGLGRTYIPS
                     IIITILTGARVPLAYFISRPEMLGLNGVWWSITLSSILKGILMISLFISLLKLGKLYK
                     ISE"
     gene            25021..25725
                     /locus_tag="PC465_000561"
     CDS             25021..25725
                     /locus_tag="PC465_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2647892.1"
                     /translation="MKEPIYKVIENHVRELINSDSLKEGDLIPSEKQLSEEFNVTRMT
                     VRSALNNLVKEGYITRQRGVGSIVIANNIYDNISSVSGFTKEMESKGYKVSNILVSLE
                     IVQADENLSSKLNISLEENVWEIKRVRLANDARVSYMITYMPVKLFPNLNKTHCEDSL
                     YNFVEEVCGYKIAMSEREVQAVISNEECMDNLKLEEPEPLLYISQICKLQNSEIFEYS
                     HTYHYGYTLTLNAVVE"
     gene            25925..26236
                     /locus_tag="PC465_000562"
     CDS             25925..26236
                     /locus_tag="PC465_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2647893.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMEDAAKENGIEAKIWAISEVNLKN
                     EIENCDVLLLGPQVRYVLGKATEMAKPYNIPVEVINMMDYGRCNGKAVLDRAVELNSS
                     K"
     gene            26258..27571
                     /locus_tag="PC465_000563"
     CDS             26258..27571
                     /locus_tag="PC465_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2647894.1"
                     /translation="MEKFMSFMDKYIVPVAAKIGAQRHLVAVRDAFIVMIPITMVGAL
                     GTLINNLPLEAYKNLMASIFGENWTTFGGDLWWGAIGTMAVFLVIGVAYFLAKSYESD
                     GLQSGLIALSIFFIMAPQIGKIVPEGGTTVVEGWGMIQQTYLGTAALFSSILIGLLST
                     EIFVRLSKVKKLTIKMPDGVPPAVSRSFAKLIPGMLTIMIFTVIGIFIKMLSNGSFLT
                     DILNTYLGAPLSNVADSLGSTMLIAFIIHILWTVGLHGANIALPFTETILMKLGGENA
                     ALAQAGATEGYHVLAGAFFDAFVYLGGSGMVLGLIVALLIAGRRRKEMIVLGGPPAIF
                     NIGEPLIFGLPIVLNPIFMIPFVLAPVICSAVSYLAIDFGLVAPVILPKIPWVTPPIL
                     GGAMATGDWTGGALALFNLILSILIYIPFVIASEKMEANKLKINN"
     gene            27648..28958
                     /locus_tag="PC465_000564"
     CDS             27648..28958
                     /locus_tag="PC465_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDF2647895.1"
                     /translation="MKKGLKIVTIGGGSSYTPELVEGFINRYEELPVKELWLVDIEAG
                     KEKLEIVGNLAKRMVKKAGVDMKINLTLDRREALRDADFVTTQLRVGLLDARIKDETI
                     PLSHGVMGQETNGAGGLFKALRTIPVIFDIIKDVEELCPNAWMVNFTNPTGIITEAVF
                     KYTNFRRYIGLCNVPIHLKNDVAKLFNVESDRISMDFAGLNHMVYGLNVSLDGEDVTK
                     EAIDKFVKADISMQNIKAIDFNAEFVKSLGAIPCPYHRYYYKTKEMLEDELREFKEGK
                     ARGQVVKELEEQLFELYKDEKLDVKPPQLEKRGGAYYSDAACNLISSIYNDKKDIQVV
                     NTLNKGSIRDFKDEQAVEVSSVITKNGPKPISIGYLPDSVHGLVSQIKSFEVLAAKAA
                     VYGDYESALLALCTNPLIPSDDLAKTILDEMLEAHKDYLPRFNR"
     gene            28984..29715
                     /gene="chbG"
                     /locus_tag="PC465_000565"
     CDS             28984..29715
                     /gene="chbG"
                     /locus_tag="PC465_000565"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HDF2647896.1"
                     /translation="MTKIIINADDFGYCEAVNYGIISAHNNGIVRSTSMMANMPGVEH
                     GVGLLKENKTLNCGVHMTLSCGRPLLSNLKTIVDKDGFFIRRITDEIIEKMDCDEIYR
                     ELCAQIDRVKGLGIDISHLDSHHHIHTLVSLKPVIEKIVTKYNLPIRGGFEYNLEYSK
                     VVPLIDSFYKENVSEEYFIKNIDEIMKYDVVDIMSHPAFLDDYILNSTSYAIDRTKEH
                     KILTSKKVKEFLEKNGLVISSYRDI"
     gene            29728..30045
                     /locus_tag="PC465_000566"
     CDS             29728..30045
                     /locus_tag="PC465_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2647897.1"
                     /translation="MDEKMIEISFGIIGFAGDAKGLAFEAIKEAKSGNIDKARECIEK
                     SKESIHKAHKFQTELIQNEANGNKTEISVILIHAQDHLMTAMNFQQLAEEFIDVYERL
                     ESK"
     gene            complement(30157..30621)
                     /locus_tag="PC465_000567"
     CDS             complement(30157..30621)
                     /locus_tag="PC465_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016208838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647898.1"
                     /translation="MVHLVYCDNAGKKGEKVLDKILAGTKTMVIRGAAGRKIPHSRVF
                     EDELLYFMEKGTAKISAKATVKKVENYVKLTEDEISKILNENQPKLNLSEKQKVRWHK
                     KCLCLVEFENVEEITPLDFDHQGNMDDWLIVEKIEDVVVGTSIPYNYEKSKF"
     gene            30891..31829
                     /locus_tag="PC465_000568"
     CDS             30891..31829
                     /locus_tag="PC465_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2647899.1"
                     /translation="MKKIKSLAIFISIITTLVLVTACSDKNTEDKDKSETRVVQSVKG
                     EVKIPSNPKKIVDISGSSEELLLAGYKPVATANVDSYETDKLPSYIREELKGVKIVGH
                     SMMDTMDMEAILEVNPDLIIMSQRQEKIYDQLKEIAPVVMMKDYANDWRSKLTDVSKL
                     FDKEEEAKSWLQKYDEKATKLGKEVIEKNGEKTYLPVLASSGQFMVFSDGGIGTLIND
                     DMKLARPKNMPKQDGITLPMVSMEGLTDIDADHIVVIATEADKKDLENSAIWAQIRAV
                     KDGNVTILDAVPFFSQSYNPIGKELLLESVKNELTK"
     gene            31957..32970
                     /locus_tag="PC465_000569"
     CDS             31957..32970
                     /locus_tag="PC465_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF2647900.1"
                     /translation="MTKLSKKNITYLLILVSIVVLVFGIVLSITIGAKDMNLSTVIDS
                     LIKMEDGINMRIVKDVRLPRAIAAALVGGFLAVSGAIMQGITRNPIAEPSVIGITQGA
                     TFAISISLVLQKKLPQLIHGSFSVMMFAFIGASISGLFIYFISSKSRGRVNNVKLALA
                     GVALGTLLISLASAISMYFNLSQQLSFWISGGLVGVKWEGIKLLFVAGGIGFILAIIM
                     APRITILSLGEEVAIGLGQKTNFVRFICIVLVILMTGASVSVSGNIIFIGLIVPQIAK
                     GIVGSDYKYIIPSSLVLGAVLLVYTDILSRMINPPYETPVGSITALIGVPIFIYLVRK
                     GEK"
     gene            32976..33998
                     /locus_tag="PC465_000570"
     CDS             32976..33998
                     /locus_tag="PC465_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF2647901.1"
                     /translation="MKNIIKINSKTLLVISILMVLIFITFLLSLNMGSFSIEPMDVIK
                     TFLGKGQRNHEIAIFKLRLPRIVIALLVGSALSTAGVILQGVTKNDLADSGILGINSG
                     AALFVVVYIYLMNGNVYEGMSNLTVFTMPIVALIGALFGAFLIYSLAWKGGINSSRLL
                     LIGIGVNIAFTSILTIFQLKFTTQEFNRVMAWTSGSIWGTSWKYVIAVLPFIVIFMGI
                     TIYKSKYIDVLNLGDEVSISLGVDVEKQRRRLIIYAVILSGVSTAVAGSISFLGLIAP
                     HIGRKIIGPKHKRLIPVSALIGTLLLLIADTISRNLLAPIEIPVGIVVSIIGVPYFIY
                     LMLVND"
     gene            34013..34795
                     /locus_tag="PC465_000571"
     CDS             34013..34795
                     /locus_tag="PC465_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004460318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2647902.1"
                     /translation="MNCINTKNLNVSYGNTDIIKNLNLNIPKGKITTIIGANGCGKST
                     ILKTIGRIISPNSGKIYINGEDIYKKKSKEIAKDMAVLPQSPQAPSGLTVSELISYGR
                     FPHKSGFGNSSKEDREIVNWSLEVTGIAEFKDRNMEDLSGGQRQRAWIAMALAQETDI
                     LLLDEPTTYLDLAHQLEILKLLDELNKKQGRTIVMVIHELNNAARFADHMIGIKKGKI
                     VCEGDAYDVMTKDNLKELFNIDAEIATDPRTNKPICITYDMV"
     gene            34807..36147
                     /locus_tag="PC465_000572"
     CDS             34807..36147
                     /locus_tag="PC465_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2647903.1"
                     /translation="MENQEALRHEKIWILLFRYSIPAIIAMMVTSLYNVVDRAFIGSM
                     EGIGSIAIAGLGVTMPVFTLIIAFGMLVSVGASTRLSIKLGERNREEAEKILGNALTL
                     SIIISLIITILGLVFLEDILFILGASKDSIFYAKDYMSVILVGSIFNLVAFYLNNAIR
                     AEGNPKLAARTMIVGCVLNLILDPIFIFVFNLGIKGAAIATVLCQIVVFFWVIHYFIR
                     GKSNLKLKKCNLKLNKDIVKKVFAIGMTPFAMEVAISITHMFTNNSLKVYGGDLAIGA
                     MTALTSILLMFMMPVFGLNQGMQTIISYNYGAKQYERAKKTLILSIIVSVVILSFGFL
                     VVQVFPEVFVGIFNKDSDLMDIAVRGISLNLITLPIMGISIVGPVYFQCISKVKHSMF
                     LTLLRQFILFIPLIIVLPIQFNLDGVWLAQPVADFIAMIIVLLFLKREFKTSRV"
     gene            complement(36242..38521)
                     /locus_tag="PC465_000573"
     CDS             complement(36242..38521)
                     /locus_tag="PC465_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2647904.1"
                     /translation="MNFENTKNKKIIATLLLTLLLIVSLTCVTFIMNLNKVTHNETER
                     YLVEVSQGISTTINVKCKSIFRTLYSMGDTYFEINDSEKEVNRYLSKKLKLFEFDWLG
                     IIDSNGNFVSALKDTGNVKGQDFYRKALQGKETITPVKSQSGTYGILYSVPLYNGDKI
                     VGAVAAWNTIDTMRNLLSVESFHGEGFSQIIDQDGNFIVSSANKNAPKNVVNFFDMIK
                     HQGKQVDKNKLEEMKINLKKNKTGSMYYTLNDGISKAMHYLPLQEENLYLLSIVPTKT
                     ASAQFDLLLKKAIFINILIVILFLLLIILIMFINQKNRAQLIKIAYVDSVTKGYSKAR
                     FDIEAKKIIQSSSSESYSLVSINIQKFKLINDSFGSEAGDKTLKYIHDVISNYLEPGE
                     LLCRVSNDQFNVLIKTIPQKEILKYIENITNDINSFNKNEECKYFIALSIGVYKIDDP
                     NLPLVSIQDRANVARKNNKGNIGNHPLYTCVFYSDLERLKMIKEKEMENRMEEALNNN
                     EFIVYLQPKISLKDNTIVGAEALVRWQDPNKGLIPPDEFIPFFEKNGFITKLDHYVFE
                     KVCSMIRKWIDNGETPIPVSVNFSRANLNNIDFLEKYRMLRNKYNIPAKLLEIELTET
                     LVFENLQKLINIIDQIHEEGFQCSLDDFGSGYSSLNMLKEIKVDTLKLDRAFFSSPNA
                     DNIAENHVIESIVNLAKKLNMNSISEGVETILQMDYLKKINCDMIQGYVFSKPLPQEI
                     FEKMTFGKKLEETSMDSSV"
     gene            complement(38859..40022)
                     /locus_tag="PC465_000574"
     CDS             complement(38859..40022)
                     /locus_tag="PC465_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF2647905.1"
                     /translation="MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIA
                     IPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVVGLGCDGIQAKELASEIATTGKK
                     VDYVVIQECGGTLKTVSKGAEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGI
                     ASNPSIGVASNLLVDEGGSSILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKR
                     AIAMGEDLRSGQPTPGNKTGGLSTIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGL
                     YFMDTPGQDIDSITGMVAGGAQIVIFSTGRGTPTGSPISPVIKITGNSDTYNKMPDNI
                     DINAGRIITDGAKIADIGQEIFNEIIEVCNGKHTKAESLGHREFGIYRISSTF"
     gene            complement(40035..40310)
                     /locus_tag="PC465_000575"
     CDS             complement(40035..40310)
                     /locus_tag="PC465_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF2647906.1"
                     /translation="MNAIIHANEKDNLVTCVRPLVKGEKVSIDGKSYIVNDNIPVFHK
                     MATEDVKKGDVVYKYGEIIGIATVDIKTGDYVHVHNIESTRGRGDKK"
     gene            complement(40331..41305)
                     /locus_tag="PC465_000576"
     CDS             complement(40331..41305)
                     /locus_tag="PC465_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HDF2647907.1"
                     /translation="MHILKSVKKIPGGLMVCPLLLGALFNTVCPQALEIGGFTTSLFK
                     TGAMSILALFCLCNGAQINIRQAGKPLTKGIVLTATKFIIGAVLGIIVSKFIGPKGII
                     GITPLAIVATMTNSNGGLFAALAGEYGDSTDVGAISILSLNDGPFFTMLAFGVTGLAN
                     VPIVALFAALIPILLGFILGNLDEDIREFLAPGTTLLIPFFAFPLGAALNFNQIITAG
                     LPGVVLGLGVTIITGMGGYFVMKLIRAEHPAVGAATGTTAGNAAGTPEALAAIDPTLA
                     TIAAVSTVQVAAAIIVTAICCPMLVSYLDKREKKKKSIFKTNKNIEVN"
     gene            complement(41576..43489)
                     /locus_tag="PC465_000577"
     CDS             complement(41576..43489)
                     /locus_tag="PC465_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2647908.1"
                     /translation="MKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYTNIDVVFGNLK
                     EGIPLAEKSINHGTRIIISRGGTYNMLKATYNIPIVEIKVDAYDIIKSYKEVKNSNEP
                     FGIIGFNNVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVAH
                     IVKRLNCKGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVD
                     KNFKITLFNKSAEKIFGIKKENALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTK
                     IITNRVPIIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLSKGLSAKYTFDDIIHASEK
                     TKDCIELAKKYACYDTPMIITGESGVGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSL
                     IESEFFGYEEGSFTGARKKGKAGIFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQV
                     MRIGGDKVIPIDVKIICASNKDLKNMMRNGLFRQDLYFRINILTLYLPSLKERKEDII
                     KLSEFFIHKYSNKYNKTPLIITPNIKKALLEREYEGNIRELEGMMERAVIVESFDSIL
                     LEKVSNEYTNNIVDKDNSDFECSNLDLKTLEKKYIYKIYNENNRNTTKTCEILKITRS
                     TLWRKLKEIEDDV"
     gene            complement(43666..44880)
                     /locus_tag="PC465_000578"
     CDS             complement(43666..44880)
                     /locus_tag="PC465_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDF2647909.1"
                     /translation="MNQEYVKGNPIFTNINKVPRQFPYLTDDIDTDVIIVGGGVTGCI
                     CAYYLAKNNIKSVILEKGRIAHGSTSVTTSLLQYELDDNLIDLTEVMTLKDALKAYNL
                     CTSALEELDTFIELYGNKCDYAKRDTLLYTANKLEVKAIKEEYNLRKENGFDVEYIDE
                     STNPFSFDLKSGLIAKNGGRELDPYKYSHHLIDVSLKNGLQVYENTEVKKVDLSNDKV
                     TAEVSYGYKVHGKKLIVATGYNTSLFTKRNFATKSNTFNIATKPLKNIASWKNNILIR
                     DNCDPYNYLRTTKDNRLIIGGEDVSFDDIENETLANEKYDILEQRLKSMFKDIKDIEV
                     EYKYCGCFASTLDNLGFIGPDNKNNNLWYCLGYGANGILFAILGGIMLSELYLGKQNK
                     NMKLFKVDRFDK"
     gene            45124..46506
                     /locus_tag="PC465_000579"
     CDS             45124..46506
                     /locus_tag="PC465_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HDF2647910.1"
                     /translation="MLSKNIASKVLEKCLITGGDFAEIFEEDTINNSISLIDNKVENA
                     IGGRNYGIGIRIFKGLKSIYAYTSDNSLNSLLDVAYKAAVALGKLEDGKSVILNDSIK
                     INNIHNIKIYPNSIGNKDKVSVMKVAYKSAKEFSNDISQVSVSYLDKDQKILIANTEG
                     IYVEDRRIRTRLGISSIASKGNENQTGFEGPGGCKGFEIFEEIDPEYYAKESARVAHT
                     MLHAKNCPAGNMMVAIDNGFGGVIFHEACGHSLEATSVAKGNSVFADKLGQQIASTKI
                     TAIDDGTIPNYWGSMNIDDEGNPTQKNILIENGILKSYMIDKLNGRRMGMNPTGSSRR
                     QNYKFAPTSRMTNTYIAAGEDKPEDIIKSIPDGLYAKKMGGGSVNPVTGEFNFVVSEG
                     YLIKNGEIQEPVRGASLIGKGSDILMNIDMVGNNVKQAQGMCGSSSGSIPTNVGQPMI
                     RVKEITVGGR"
     gene            46518..47867
                     /locus_tag="PC465_000580"
     CDS             46518..47867
                     /locus_tag="PC465_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HDF2647911.1"
                     /translation="MELKNFKDILFKKALSEGFEECEIYYYTGENLSINIYEGEVEKY
                     NLDKSFGLSFRGKVNGKIGYSYTEILDDKAVDMLIKNVKDGVNTIENEDVQFIYEGDK
                     HYNDVKTYSKELENLEADKLIDLALEMERETKAYSDKVVNLSKCTISYSVSSNGISNT
                     KGLNLSNKTNMLIGFVVPIIEDNGQKYDGIGYNIANSIEEIKPCEIAKLGVDNALSKV
                     GGKSIPSGKYKTILLNEAMVSLLSTFSGIFNADSAQKGLSLLKNREGDMIASPIVTIV
                     DDPLLENGMASTPFDDEGVATFKKEVVLNGKLITLLHNLKTANKAGVKTTGNGIKSSY
                     SSPISIYPTNFYIEKGDKSLDEIIKDIDEGLMVTSFAGLHSGANSVTGDFSLAAKGFY
                     IKEGKKVFPVEQITVAGNYFDLLKDIEAIGADLEFPMSSIGSPSVVIKELSVAGKDE"
     gene            48017..48550
                     /locus_tag="PC465_000581"
     CDS             48017..48550
                     /locus_tag="PC465_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF2647912.1"
                     /translation="MSDAHYDMHKRNGYSSDEPYPEIKVLGPNKYYAELLMDDYAGVS
                     SEFTSVNQYLYHNFDLDETHRELSEMWINISITEMLHMEILAKTIRLLGGNPVYRGST
                     SSCGAYWNGGFVCYGNSICNRLKLDLHLEHVAINNYYKDISLIEDPYIKAILNRIILD
                     EKLHVSLFEKAIEKYCK"
     gene            48634..49443
                     /locus_tag="PC465_000582"
     CDS             48634..49443
                     /locus_tag="PC465_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2647913.1"
                     /translation="MYYVYVNDINIAVYDLNPSAKKTVLFIHGWPLGHKIFEYQTNIL
                     PKLGYRTVSIDLRGFGKSDATSGGYTYSQLADDIYKVVHAIGLKDFTLVGFSMGGAIV
                     LRYMSLFNGYGVSKLVLAAAAAPSFVQRPPEFPYGMTREDVNKLIAQACTDRPEMVTD
                     FGEKVFASNPPESFRRWFNDIGFSASGIGTIGTAVSLRDEELFNDLKCVRVPTGIFHG
                     KLDEICPYEFAVFMNEKIEDSILYTFEYSGHAIFYDELKLFNQEFLQFLEE"
     gene            49853..51898
                     /locus_tag="PC465_000583"
     CDS             49853..51898
                     /locus_tag="PC465_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2647914.1"
                     /translation="MKKHNILFVSTDDKINIDISKQLENIFGEFCNIDNLVYVNRINI
                     ELSSYELVVCSDNDIKEYIHNNIDKNIPIVIVHRTINIENINQIISIENDSDVMVIDA
                     YKESADETAKIIRKLGLIHINLIPYYPGCDKSKCEIGIITGSRNSIPQNIKQIIDIGD
                     KVIDINTVIEIFTKLNISIDKLHIIKEKYNEDTVSGYRYYTTMNKTMKSFLEIIDEGI
                     ASVDKLGKFIYCNKVFSNLVGIDQNEIISNNFMDLFSDKVVKKIFFQEDEVNDEVVNL
                     NNKKLIINKVNVYENNERIKSIISIKNISAIQELEDKIQNKLQSKGFVSKYTFESVVG
                     ESKIIKEKINIARKIATTDFSVLILGENGTGKEIFAQAIHNESLRKNKPFVAVNLSSL
                     SDTLIESELFGYDEGSFTGAIKGGKMGIFERAHTGTIFLDEIGDISLDVQQRLLRVLQ
                     EKEVMRMGGSKIIPIDVRIIAATNKDLKKKIKEGSFREDLYYRINVLHIEIPRLRERK
                     EDIPLISKYFLDEINSNKCFTEESMQALTLYEWPGNVRELKNLIYYIDTIVEEDRVDY
                     EHLPEQFRFEKNNTLVNENFDSIILDFKQSNFFEESICILTSIETWNNKNILLGRNKL
                     QEILKEKDIVLSVDQIRKRIDKLKSHGLLLSGVKKQGSFITDEGKNFISYVKIKGVI"
     gene            52159..53358
                     /locus_tag="PC465_000584"
     CDS             52159..53358
                     /locus_tag="PC465_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HDF2647915.1"
                     /translation="MKSAYKGYEAYSYLEKGKDISSIEMCKGDKRVKEYLIELDDIQE
                     AKVKSIVDEKIFISLHEHPVLFPEHLERDIFEYNREGKQRCAYEALSRGYYDAIFDNL
                     MDGVCTITSNSGWKWDDILIDLGMRLCDLAHQDFVIKCEKVEDIYRAKSEGKVALIPT
                     LEGAAPIENELDRIDILYGFGIRLMGITYSESNALGSGLKEEKDGGLTNFGKKAVERM
                     NKIGMAIDCSHVGVQTTLDVIEYSKDPIILSHVGARSLWNTKRLTPDEVLIACAKKGG
                     VIGVEAAPHTTITEKNKEHSIESFMEHFEYIKNLVGIDHVAFGPDTVYGDHVKLHSVL
                     AAKFDIKKITGTKEHPKVEYVEGLENPTETSKNIVRYLVKHGYSDEEIEKVLGGNILR
                     VLKQVWK"
     gene            53410..54105
                     /locus_tag="PC465_000585"
     CDS             53410..54105
                     /locus_tag="PC465_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HDF2647916.1"
                     /translation="MDYLKLANHPLLWIASTVAVSIVVVQSLIFAIKSCKVGKTMGIT
                     DKQIKSAVKSSAISAIGPSMTIFAGMVSLIVTMGGPIAWMRLSFIGSVIFESMSAGFG
                     TDALGITLGSPEMTKLAFTNAVWTMILGSLGWIIFTLLFGHKLDKITNVISSGKKSFI
                     PIISLGAMLGSFAYLNADRVLRFDNGTIACISGMAIMVILCMLEKKKNIKWLREWGLT
                     ISMFSGMIIASVI"
     gene            54118..54795
                     /locus_tag="PC465_000586"
     CDS             54118..54795
                     /locus_tag="PC465_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647917.1"
                     /translation="MSKVKSIYNEEYLPFMIRYGRLTLSLGIIAALVPGIILSFGFGI
                     MPPISALLASTMAIVSMSAPNYIIEPVSYSPILGIPGTYMSFLSGNISNMRLPCSIAA
                     QKAAEVESGTEEGSIISTIGIAVSILVNISILTIGVILGGSVLSKIPAEVVEKLNLIL
                     PALFGSVFGQVFLQDKKLGLVAIVISVLTIILSKQGIIPQSLVVLICVFGTILIARAM
                     YKDKLSD"
     gene            54906..56507
                     /locus_tag="PC465_000587"
     CDS             54906..56507
                     /locus_tag="PC465_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2647918.1"
                     /translation="MIYDLILKNGFIIDGTGNPGFYGDIAIKDNLIAKIDSKINSNTN
                     KEIDCCGKVITPGFIDPHVHEEIVAILDGKFEKFLKQGVTTTINGNCGHSITPYSSEN
                     VYEYMYKNGLLLEEEKKYLIDKNKCWNNFTEYCDLISKSGISVNMGFLLGHGTIRWSV
                     MGGSKDRPPTEKEKNEITDIINDGMKSGAFGISTGLAYIPSKYADIDELVDIARQIKE
                     YDGIYTSHIRDYIGRYNAVKEAIEVGQKSGARVQVSHLSPVEIEAFDDILKARYNGVE
                     IMVDTVPRSSGHCMKKKRVIQFIMAISSSLFELGIDGVMDALRNEEGRTLILKEAFIL
                     GDRGSIILLNTKDINMEKKSIREIATQKGIDEDKLLLDLLLDGDEELIFCLGGMYRAD
                     FPDKLHDDKIIDNPFVMVGSDCLFSVGGDMSWFELQRRGAFPIFFNMYRKSGVRLEEI
                     VRRVTSLPARQFKIKNRGILKEGLIADIAVIDMDNYSYPRSEDIDFSKPQLLANGVEY
                     VIVNGKIALENGEITENKCGEVLKR"
     gene            56955..58244
                     /locus_tag="PC465_000588"
     CDS             56955..58244
                     /locus_tag="PC465_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDF2647919.1"
                     /translation="MRELLKVTLIVMLVLINAFFVACEFAMVKLRSSRIDTMIAEGNN
                     NAKRCKIIKDNLNSYLSACQLGITLCSLALGWMGESTVKELILPIVSVFNLSESIIYT
                     ISISISFLIITMMEVVIGELVPKALALYNTEKIMLSTSFLLVGFYKLTYPIIYFFNLS
                     TDLFLKPFGYSQADEVDEPHTGDEIRLLVEESYKSGLIDESEQRLVDNIFEFEEKKIR
                     EIMVPRTDMVCIYESDSEEKILAILKEEGVTRYPVCRKNKDDILGFVHIRDLYNQKIN
                     ENKIELEEILRDIIYISENLTIDKALERIRKEKLQLAIVVDEYGGTSGVVTIEDILEE
                     IVGEIQDEFDKEETHIKKIGAGSYLVDGTESINYINKYFGLDIEHDGFDSIGGWISYM
                     LGSNIKVNQSVTFENYNFTILELDKLRVVKLIIKSVI"
     gene            58273..58953
                     /locus_tag="PC465_000589"
     CDS             58273..58953
                     /locus_tag="PC465_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDF2647920.1"
                     /translation="MQKVEGIIFDMDGVLFDSERISLEFWMETFEKYGYTMTKEIYTS
                     VMGRNRKGIIEGLTDIYDSSVPIIDLYDEKTKNMIEFMERKGAPIKLGVNELISFLKE
                     NGYKMAVATSTKRERAVKRLAKANLKDYFDAIVCGDDVVNSKPNPEIFLKAAKKINVN
                     PKNCIVIEDSPMGVEAAYNGGIRCINVPDLKEPDEQIKSQSHKILENLLEVREYLKSL
                     NSKECHNL"
     gene            59054..59593
                     /locus_tag="PC465_000590"
     CDS             59054..59593
                     /locus_tag="PC465_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HDF2647921.1"
                     /translation="MDNVGSLLYFLFNFFLYGFIGWIIENLYSYYKQGHFQEDGFLNG
                     PFKPMYAIAMSIIIEVSRFIDPNNIFALLLLCLVVPTVVEYITGILMKVYFNKVYWDY
                     SDYKYNSRGIVCLKFSVYWTILTFIGVRYFQVYIVDSLYSLIIPYWPIVVTILLVTLF
                     VDEILTIKFLRGNKDIVER"
     gene            59769..60788
                     /locus_tag="PC465_000591"
     CDS             59769..60788
                     /locus_tag="PC465_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDF2647922.1"
                     /translation="MMGKIRFGIVGTSNIANIFLRAASRVKDFELVAVYSRNLEKARE
                     FGTLYGASIFFDDLEQMAKSKDIDAVYIASPNALHSKQTITCLKHKKHVLCEKSLASN
                     LKEVKSMIKTAKDNNVLLMEAMRITCVPNFKAVKENLYKIGKIRRFFGSYCQYSSRYD
                     KYKNGIIENAFKKELSNGALMDIGVYCIHPMVNLFGAPKTVKAVSHILQTGVDGEGSA
                     VFQYDDMDAIIQYSKVADSYIPSEIQGEEGSIIIEKLNLFEKAIIKYRDGREEDISIP
                     KEKAEEKPREIEGMYYELVEFISLINNNKIESNINSHENSIIVMEIMDEIRRQSSIVY
                     PADSI"
     gene            61076..62266
                     /gene="dltD"
                     /locus_tag="PC465_000592"
     CDS             61076..62266
                     /gene="dltD"
                     /locus_tag="PC465_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HDF2647923.1"
                     /translation="MRKLIYFITPFIIGVVFLFGLDKFLDSKTDELLREKNLLPIMDD
                     TLSDIKDKGVTANNHFLREKDIMILGSSELSNSTKQHPKYYFNTNRSKNKVFAIGRAY
                     TQTLQDAAILGSMNPNIDNKKVVLLISMQWFMEKDGVTSHHYQSRFSPIQFYRFLDNP
                     KISKQNKIEYAKKSSKLLWGSDEYKAEALYAKLYEPKTFPEKAEKVLLEPYFQGRKYC
                     IALKEKGILYKRLIKLDKKRATKRKRPINWSYERKKAIEDAKKRVGKNPLNIDKYYYK
                     EHFKDGIEQYKGRDKDVNLLTSKEFENYKLMLNVCTDLGIKPVVVLIPSMDKFYNLTG
                     ISEKERNQYYDKAQKIAESKGFEVLNLKDKGSDKYYLRDVMHLGTKGWVDVCERLFKI
                     FKEQ"
     gene            62387..63901
                     /locus_tag="PC465_000593"
     CDS             62387..63901
                     /locus_tag="PC465_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase"
                     /protein_id="HDF2647924.1"
                     /translation="MKIIEGIKKYSNTDRTALMCNGDKLSYKDLNEYSDAISVFLKDV
                     YKEEDTPIVIYGNKENMIMACMIGALKSGRAYVPLDISFPIDRVFEVTKEIKPKVLFN
                     FSDERNFGDINVIDMDKLNYIINEYQGKSLDKENWVKDDENAYILFTSGSTGKPKGVQ
                     ISSNNLDSFSDWISPYLNIDGSEKVIMNQPAYSFDLSVTTIYPGLIHGATLFSISKDV
                     LADYRELFRQFSISDIAVWVSTPSFAGVCITEKEFNSKMLPNLESMIFIGEALSKNLT
                     KELMSRFPNTRIINGYGPTEATVGVSVNDMTQKAIDDEKSLPVGYPMSNCKIKILDED
                     GNELKENEKGEIIIIGPSVSKGYFNNKEKTDEVFFYDEIDGVKWRAYKTGDMGYLLDG
                     NIYYCGRKDFQIKLNGFRIEIEDIENNLRKVHNVKNAVVLPVYKDEKIAYLKGIVELN
                     EKNDLSNIKNGRIIKKELGKYIPSYMIPRNISIISEFPTNINGKIDRKKLMEEI"
     gene            63901..65049
                     /gene="dltB"
                     /locus_tag="PC465_000594"
     CDS             63901..65049
                     /gene="dltB"
                     /locus_tag="PC465_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HDF2647925.1"
                     /translation="MIFSQYGDYFYLYILLLTSIPSVILGLMGKNIKYYGMLASLFMI
                     FLIVGIDVQLKYLVIFIILEIIIVKGYEYVRRKTKNKYIYWGFLFASMLPIIINKISP
                     VTSFGIIGFIGISYLNFRTIQMVIEIYDGAIKEVKISKMLYFMLFFPTLSSGPIDRSR
                     RFEQDLEKQISRKEYIEEYLLPGIKNIVMGVGYKFVIAFLINTYWVSRIPKDMSFINI
                     LSYMYAYSLYLFFDFAGYSLFAIGTGYIFGIQVPINFDKPFISKDMKEFWTRWHISLS
                     RWFGDYIFSRFVMSSMRKKRFKKRTTAAHVAQMITMITMGFWHGLTWYYVAYGVYQGL
                     ALVLTDIYQRKSKFYKKHKKDKWFERVQIFITFHIVCFGLLIFSGYLA"
     gene            65068..65298
                     /gene="dltC"
                     /locus_tag="PC465_000595"
     CDS             65068..65298
                     /gene="dltC"
                     /locus_tag="PC465_000595"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HDF2647926.1"
                     /translation="MQETVIEIFEDVLGTDEIREDLDLNLFETELLDSLAIIEVLLEI
                     ENRLGIELQPTDLERKDMSTVNNLVKFLETRK"
     gene            65515..66300
                     /locus_tag="PC465_000596"
     CDS             65515..66300
                     /locus_tag="PC465_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDF2647927.1"
                     /translation="MSLNSIDRKKEILKLLDSKGKVNTKELVKRLEVSSETIRRYLEE
                     LENENKLKKVYGGAIKINYGVIEPEHIKRNNTNLDKKQSIAKYAAKFVNDNESIIIDE
                     GTTNLQIVDYIISVNNLKIITNSYPVLSKLISYENQGLFDGEVIFIGGKVNLKHQRTA
                     CPMSIDTMKNLYVDKAFISSEGILDSFGISSIDQNKALLSKEYIKNSKESFVLCDSSK
                     IGIASMYKIADLEELDFVICDVEPPNEWKDKLSEINITWIEAK"
     gene            66579..68489
                     /gene="phnW"
                     /locus_tag="PC465_000597"
     CDS             66579..68489
                     /gene="phnW"
                     /locus_tag="PC465_000597"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HDF2647928.1"
                     /translation="MKKIYGEKIKAVVFDWAGTTVDYGCFAPLNVFIEIFKRRGIDVT
                     MEEARKPMGKLKIDHIREMCEMDRIKNIWSDKFGKVPTEDDVNELYAEFEPMLFETLE
                     DYTTPIPHVVETIEKLRKNGLKIGSTTGYTREMMNIVEPNAAKKGYSPDFLVTPSEVS
                     QGRPYPWMCYKNAEALGVSPMSSMVKVGDTISDVKEGVNAGMWSVAVIKGSSELGLTQ
                     EEVENMDKEELKAKMSIVSKKFKEAGAHFVIETMAELEDILIKIENETIKSDFVPEND
                     YILLTPGPLSTTKSVRASMLKDWCTWDIEYNNLVQDVRRRLVSLATQNTDKYTSVLMQ
                     GSGTFSVEAIIGSTISKDGKLLVIANGAYGKRMKDICNYLNIEFVDCTFKDIEAVDLN
                     VVENLLKENKDITHISMVHCETTTGRLNPIQEVGKLAKEYNKIYIVDAMSSFGGIEID
                     VEDFNIDFLVSSSNKCIQGVPGFGFIIANKEKLSKCKGIAKSLSLDVYAQWETMEENN
                     GKWRFTSPTHVVRAFYQALLELEEEGSVEKRYARYKENQFTIASRLKSLGFDTLVNDN
                     AQSPVITTFLYPKNAKFEFMEFYTYLKDNGFVIYPGKLTDIDTFRIGSIGEVYPTDME
                     RLADVIEKFINR"
     gene            68848..69669
                     /locus_tag="PC465_000598"
     CDS             68848..69669
                     /locus_tag="PC465_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647929.1"
                     /translation="MNEELSSLRFDGVGKCKGGIFDNVNISGTGKIEGSVKCSKFDSS
                     GSAKVFGTTECNEFFTSGLSKVEGNILASKVEISGLLRCTGNINSVEIDTSGIINVEG
                     SIKSDIIHGEGYLKANENIDCENINLSGILECNGFLNCEEVNISLNGTSNFNEVGASS
                     INIKKGHGDYCKKFRMLEKKHINFEKVSSNLISLGLLSIRKYTESKLFANIIEADEIS
                     LENSEVKVVRGKNIKIGKGCYVESLEYSESIEIDEDSIVGEIKNISEKIKLKKDK"
     gene            69710..70477
                     /locus_tag="PC465_000599"
     CDS             69710..70477
                     /locus_tag="PC465_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="HDF2647930.1"
                     /translation="MEKGSIKILGEGFISSGEYENIKIVGSSKSKGNVKSNEVKVLGD
                     AKFEGDINIKNFVVNGKTIIRGNLKAERVRVNGQLNIEGDAEIDDLVITAQQKVDGKL
                     KCNNVTIRGQLSVNENMYAQDIKIYGEMRNKSNIECEDIKVYGAIKCDGLLNGENIYV
                     YSGGGSYCKEIGATNIKIGRSKDAFSLIKIINIFSGKFKCNLIEGDTIELEDASIKDI
                     RGKSISLVDNCDVVNIEYSDNLSVSDNSTVKNSIKVG"
     gene            70485..71105
                     /locus_tag="PC465_000600"
     CDS             70485..71105
                     /locus_tag="PC465_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbD family protein"
                     /protein_id="HDF2647931.1"
                     /translation="MEELISKKDLLSKTNISYGQLYRWKRKNIIPEEWFIKKSAFTGQ
                     ETFFPRDKILERIELILSMKEETSLDDIANMFMKKDINKEFDIDFILSKEVICNYTKE
                     IFQNLYKKEQSIGKKELLILSIIEKFLVKSIITFEELKLIVNIIEENFTSIYNESGKI
                     YLFRKFGVPFVVGCLDYKKVKFEKDVVKIIEIDLTKEINDISIKLS"
     gene            complement(71405..71992)
                     /locus_tag="PC465_000601"
     CDS             complement(71405..71992)
                     /locus_tag="PC465_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HDF2647932.1"
                     /translation="MNLKDSKTKENLLRAFAGESQARNRYNISASVAKKEGLYIIESL
                     FNYTADQEKSHAKQFFSKLKEFAGENISISGAYPVDLYDKTAQHLKAAQHNELQEWDD
                     VYKNFGKTAREEGFESIAKLFENIAEIEKVHGDRFGRYATDLEEGTLFRRNEDIQWIC
                     THCGHIHIGKEAPKACPVCLHPQGYFLDFKNSLFE"
     gene            complement(72078..72515)
                     /locus_tag="PC465_000602"
     CDS             complement(72078..72515)
                     /locus_tag="PC465_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2647933.1"
                     /translation="MEDKYIVHFISKTKASMIKFIENKLSKNGLGELIPTHGNILTAL
                     YENNGILTMKEIAAKIGKDKSTVTVLVNKLINLGYLERQKCTNDKRITYIKLTKKALL
                     IEDTFNSISTQVKETAYHNITENEKQEFLRILKKINDNFKNAD"
     gene            72619..73617
                     /locus_tag="PC465_000603"
     CDS             72619..73617
                     /locus_tag="PC465_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdH/YhfP family quinone oxidoreductase"
                     /protein_id="HDF2647934.1"
                     /translation="MNKKFKSLYITEEEGNFRRNIVEREVDTLPEGEVLIKVKYSSLN
                     YKDALSANGNKGVTRKYPHTPGIDASGIVESSSCDDFKIGEEVLVTGYDLGMNTSGGF
                     SEYIRVPSSWVVKLPKNLSLKEAMDYGTAGFTAALSVYKFIDSVDKNMGDVLVTGGTG
                     GVAVIATKILIKLGYSVVVSTGKLEEQKEVLLNLGVKDVIHRSEVDDNSGRPLLRPRW
                     AGVIDTVGGNTLATAIKTTNYCGAVTTCGNAGGVDFTSSVYPFILKGITLYGIDSVDC
                     PMNLRLKIWDLLSNEWKLDDLDDMVNVVSLEELNDSIDSIMAGKHVGRTVVDLEKI"
     gene            complement(73737..74663)
                     /locus_tag="PC465_000604"
     CDS             complement(73737..74663)
                     /locus_tag="PC465_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HDF2647935.1"
                     /translation="MSKENKNVRIAVVQASPVIMDLEKTVEKALGLIKEAGRKGANIV
                     VFPEAFIPAYPRGLSFGFVVGSRTMEGREDWKRYYDNSVPVPSATTDLLGKAAQEAGV
                     YLSMGITERDGNDINCTLYCTNLFFSPEGKLIGKHRKLKPTGTERCIWGEGDGSTLTV
                     VDTPYGKMGSLICWENYMPLARTALYAKGVKLYIAPTADSREEWQATMKHIALEGRCF
                     VIGCNQYVEKNMYPTDLNYYKELDAEPEIMCPGGSCIVDPFGKYVAGPIFNKEEMLIA
                     DLDLEKIVLSRLDFDSEGHYSRPDVFELIVHE"
     gene            75049..76653
                     /locus_tag="PC465_000605"
     CDS             75049..76653
                     /locus_tag="PC465_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2647936.1"
                     /translation="MKEKIYYNGNIITMEDSICGDAILIKDKIIKKIGTKEEVFALKN
                     KDTEIIDLQGKTLMPSFIDSHSHLIAFATTLKLVPLEDATSFKDIVKKIQDFKESNNI
                     KKGDWIIGFSYDNNFLEENKHPDKSVLDSASSENPILISHASGHMGVANTLGLKQLGV
                     TNETRDPEGGHIGRVEGSEEPNGYLEENAFFNVASKIKQPSSNEIFNSIEKAQNIYLS
                     YGITTAQEGLMEENQFNILKAMANQNKLKMDVVGYVNLKKSKSVVDNNREFIKKYINR
                     FKIGGYKIFLDGSPQGKTAWLSRPYENSDDGYCGYPIYKDEEVEKFIDISLKEKMQLL
                     THCNGDAAADQLIDAFEKVLNLKEQSSENNIRPVMIHAQTVRADQIDDMKVINMIPSY
                     FVAHTYYWGDIHIKNLGEDRAFKISPLKTTIEKGLIYTLHQDTPVIAPNMLETVWCAV
                     NRITKKGIQIGENEKISPLDALKGVTINAAYQYFEEDKKGSIKEGKLANLIILDENPL
                     TIDPMKIKDIKVLQTIREGEVLYSLK"
     gene            77469..78740
                     /gene="serS"
                     /locus_tag="PC465_000606"
     CDS             77469..78740
                     /gene="serS"
                     /locus_tag="PC465_000606"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDF2647937.1"
                     /translation="MLDIKRIRENLDCIKKAMERRGEKDFNLDEVVKLDDERRKILQE
                     VEVMKNELNTASKNIPNLIKEGKDVENEKIKLKELSDKIKVIDQNLKEVEDKMEYLLM
                     RIPNVPHPEVPQGETDEDNVEVRTWGKTTTFDFESKAHWEIGTELGILDFETASKITG
                     SRFTLYKGLGARLERALLNFYLDTNTKVNGYTEVIPPFMANRNSFLGTGQLPKFEEDM
                     FKIEGMDYFMIPTSEVPLTNIHANEILKFEQLPINYTAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVEMVKIVAPEESYNELEKLTNNAETMLQLLNLPYRVVKICTGDLGFTASFK
                     YDVEVWMPSYNRYVEISSCSNCEDFQARRAGIRFKRDKDSKAEYVHTLNGSGLAIGRS
                     VAAILENYQQEDGSVVVPEVLRPYMGVSVIK"
     gene            79109..80614
                     /locus_tag="PC465_000607"
     CDS             79109..80614
                     /locus_tag="PC465_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF2647938.1"
                     /translation="MKIQNTEWGYIEWKHTYDENNPKQAMNIYIAVTMPGKKHFNHVH
                     YGQEQMIYILEGEGLYIINGVWKPFYQGMIFYIESGSTHETINTGDREIKELIVSNNV
                     DDVGESEVIDINPNNYLKKTLINYSESTLNLYAAVESIRGQFIDPFKIPLIIYDDSWN
                     IVLKNPYFPLFCFEKCNPMKFPQNCDCMNQKSSNQFVCEYGITIYNIPILYKSNSIGV
                     IRGGYVLLSDLNLDTEHNNLYDIPEGAARSIKRLLKQISKNIINFCSFNDIRKDLQEK
                     EKTIARTYHYGEQLEMNLKVAQDMVTNLRINHHFLFNTLNSMASIALDDGSYDLYSAI
                     IDLSRMFRYTMRSDLRFVELESEILYIKNYLNLQKLRYGDALKVKYLIPEKLYNLSVP
                     FNFIQPIVENAFTHGFRDIDTEKRIEIIARLDSQYAIIEIHNNGTILDGNNIDKIKAG
                     IRSNNGHGLSLIYTKFTSAYGNNFDMDIKSSDNEGTYIMIKIPIENYKEYV"
     gene            80728..81426
                     /locus_tag="PC465_000608"
     CDS             80728..81426
                     /locus_tag="PC465_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDF2647939.1"
                     /translation="MRRALIIDDEEAVLKIITHFIEMKDMPIKIVGKATSGDEAVDKI
                     IGLEPDIVFIDIQMPIYNGLEVIEKTSHLSKKINFVVITAFNYFEYAQKALRLNVKDI
                     LLKPLDMKEFTKSVEKIIGYQYTNNDLLNEILEYINLNYSNDLKLNDCARLFLTNPSN
                     ISRIFKSNLNTTFISYLNHIRIEKSIELLENTTKSINEIAEIVGYNSLNNFYKNFKIE
                     KGMTPKVYKLNTKN"
     gene            81711..82799
                     /locus_tag="PC465_000609"
     CDS             81711..82799
                     /locus_tag="PC465_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647940.1"
                     /translation="MSDKVNMKNIICIAGAYLATAIGSGFATGQEILQFFASQGYMGL
                     IGALISMVLFSFLGAEVITRGRELKLKEPTRIYTFYCGKILGKFYEWFSPIFLFGILI
                     VMISGAGSTLTEYYGINPYLGRVLMAVATLITVSMGLEKLVSILGRIGPVIAVFTIAV
                     GLISLFKHFDGLSMVGEAMKNIEVTKASESPIVSGVIYNTLNIIVMIVFLTGMGASIE
                     SKKDAFWGGLLGGIVFMTAGIVMYLAMISDIGNLYMKEIPSLYLADNISPIVGVCFSV
                     ALILGIYTTAVPLLWSVTNRIVEDEHPKFKLVTTVIAILACIGGFLPFGKLVNILYPY
                     TGYMGLLILVCMVYKAITCRKKSTQSQE"
     gene            83038..84228
                     /locus_tag="PC465_000610"
     CDS             83038..84228
                     /locus_tag="PC465_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2647941.1"
                     /translation="MHELILISEKYKEDILDFFTDIHMHPELSFKEFRTTKAIKDLLV
                     SLDIEILDLGMETGVVGLLKGKYDGPTVALRGDIDALPIYEEVDIKYKSRYDGIMHAC
                     GHDIHTSCLVGCAYVLSHIRDSLHGNVKFIFQPAEEVNKGAKMLVERGVMENPKVDAI
                     FGLHNHPDIPCGKIGVKLGGLMAAVDTIKIEVNGFGGHGGIPNRTIDPIVASSAIIMG
                     IQTIVSRNISPLESAVISIGTINGGTANNVISEKVDMTGTCRSFSNEVRKKISENLEN
                     IVCEIARGYQATAKLDYLFDLPAVINSKEMYAIACKSVCDLYSEDAIVDPIPSTGGED
                     FSIFMEKAPGFFYWLGVGNKEQDCIYQWHNPKFKADKNSILVGTNVLCQSVINYMDKL
                     KNKI"
     gene            84319..85821
                     /locus_tag="PC465_000611"
     CDS             84319..85821
                     /locus_tag="PC465_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HDF2647942.1"
                     /translation="MRALNVVERAGNKLPDPVTIFLLLCIIVVILSAVISNLGVEEIH
                     PSTKEVVKVVNLLEKEQIQSYLGSIVTNFQSFAPLGLVLVTMLGAGVAEKSGFMEVLM
                     KKGISKVPQKLVTVAIVFAGMLSHTAADVGFIILPPLAALVFLGIGRHPLVGMFAAFA
                     GVAGGFAANVMLSTTDVLLAGFTIPAAQMMDPSYQGNPAMNLYFAFISAIVLTFAGAF
                     VTEKFIAPRFTKYNDSTNDKDIQELSELENKGIKYALLSLLVVVVVIVALCIGDNAFM
                     KDPETGSILSSNAPLMKGIVPIITIIFLTPGLVYGKVSKKIKSDKDLVSMMGSSMSDM
                     GGYIVLAFIASQFINLFNLSNLGTILSITGAKLLAESGIPSYGLIIGFILLSGFINLF
                     VGSASAKWAILAPIFVPMFMLLDFNPALTQIAYRIGDASTNPISPLFPYFPVILAFAR
                     RYDKDIGIGTVISNMIPYSVVFTLIEIIILLLFMGIGIPLGPGGGISYVL"
     gene            85893..87149
                     /locus_tag="PC465_000612"
     CDS             85893..87149
                     /locus_tag="PC465_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDF2647943.1"
                     /translation="MLKTTKISDPELYKIVADELVRQEHNIEMIASESTAPTEVLELS
                     GCVFTNKTEEGYPGARFQAGSEEADKLETLAIKRAKEVFGAEHVNVQPYSGSTANYCV
                     YSSILKPNDTVLSMRLDQGGHLTHGSAVNFLHDIYKYEFYGVDPNTGRIDYDALEAKA
                     KECRPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAHVAGLVAAKVIPSPVPYA
                     DFVSSSTTKTFCGPRSGIVLCKAEHAKKLDKGVFPGTLGSIHLNTVAAKAFSLLYLST
                     DKFKKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRSKNLTGKQFEKALEY
                     VGITVNKNVIPDDPQSPFVTSGVRIGLTSISQRGLKEKEVIQIAGIMNKVAENIDNKE
                     VLDECKAEAQELISKFPLYPEGYFED"
     gene            87321..90095
                     /locus_tag="PC465_000613"
     CDS             87321..90095
                     /locus_tag="PC465_000613"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HDF2647944.1"
                     /translation="MRYYNKPTKEVLKYLKTNPEIGLDDNEVEERKLRYGLNEFTIKE
                     GRTFWDELGESLTEPMILILIGAAVISSFVGELHDALGILGAIFIGISIGIITEGKSK
                     KAAHALSKLTENIEVKVLRNGKIIKISKNDLVPGDIVYIETGDMIPADGRLIQSINLK
                     LREDMLTGESDDVAKNADAVLDMEVVYSKTEIIEQDAIPAKQVNMVFGGTLVAYGRGI
                     MVVTHTGDKTEMGKIAQNLSNEDQQTPLQIKLGKLGAKIAGISGIIATLLCMFMIIQM
                     QRKGMLILDTSSVLSFLQSLEPAKNAYMVCIALIVATVPEGLPTMINITLAITMQKMA
                     KINALVTKKEACETIGSVSVICSDKTGTLTQNKMMVEVAYVDGKYISGGEYQSNSYFE
                     QNCIVNSTADIEKEDNSFKYIGSATECALLLYHNDKNYNEMRKQTYLISQIPFSSEEK
                     KMSTLIRQEDSDILLSKGAPEVLLKKCSYVQQGKNIVPITPKVEKSILDEIKKLQIKS
                     MRTLGFAYKKMSNSKTEVAMTSEGELNLIGNSRSYMKEDNLVFSGFVGIVDPLREGVK
                     DSIDKAFNAGVDVKMLTGDNINTATAIGNELGLLNDGKKAVEATYIDVLTDKELREEI
                     KGISIVARSKPDTKMRIVSALQKSGEVVAVTGDGINDAPALSQADVGIAMGISGTEVS
                     KNAADIILTDDSFSTIVEGIKWGRGIYENFQRFIQFQLTVNIVAFIIAIISQLTGKDM
                     PFTTIQLLWVNIIMDGPPALALGLEPVRDYVLKRKPINRHSGIIARSMFVNIIINAIL
                     IITIVFTQSAFNILGATSEEQGTVIFSLFAFSALFNALNCREFGLNSTIPNFFKNKLA
                     LQIIVVTGIIQIIFTQVFQSFFNSVSLDFDMWIKIILFASTILLSNEFVKLILRTMKN
                     SRTMNFNSKN"
     gene            complement(90160..90345)
                     /locus_tag="PC465_000614"
     CDS             complement(90160..90345)
                     /locus_tag="PC465_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDF2647945.1"
                     /translation="MFFISDIYTKSPIKFDTPLQKKAYKILQKLDIDFECVDTDEAIT
                     MEDCVQINKKLNMKMVI"
     gene            90720..91898
                     /locus_tag="PC465_000615"
     CDS             90720..91898
                     /locus_tag="PC465_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF2647946.1"
                     /translation="MFSKILVKTFIRDSENVQNTDVRNKYGYVAGVVGILSNLLLFVI
                     KVFIGMLTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSAL
                     IVAFMVMLVGLQFVKSSIERIVNPIPVKFEVIPLILLIASIMIKIWLSRFNKFMGNKI
                     DSSALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKD
                     TINPLLGEAPDEEMVNSIIELLLSYKYIIGTHDLIIHNYGVGRCIASIHAEIPSNIDI
                     MEIHEIIDTAEREISEKLDIYLVIHMDPICLEDKEVMSAKKELEEILKKNSLVKSMHD
                     FRIVGKGSKKNLIFDIVVNPSEFSKNMSEDDLKEDITKLVKEINPEYNCVIVVDKDFI
                     "
     regulatory      92025..92110
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            92228..95146
                     /locus_tag="PC465_000616"
     CDS             92228..95146
                     /locus_tag="PC465_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021362860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HDF2647947.1"
                     /translation="MKKGNRKALLISLIMILSMVVSTIYPTVSYASELGENSQIQSGS
                     TNSSTGEEKESDNKKPEQTPEKDKATDNKKPEQTPEEEKPTDNKKPEQTPEEDKSTDN
                     KKPEQTPEGEKPIDNKKPEQIPEEDKSTDNKKSEQALEDEKPLDNKNTEKTPEEDNLL
                     EDENLLKVLEEELNEENEDYGFVVKINNNTIETESMKKISFNLTYTPTSKGIQAGDSI
                     TFKVPDVFNKVNLDYTSECFDKTESNGEYTLTFRELPNGQSVMQGKIGLEAYVKKVDE
                     DTNAKIHIETTGKIESGSGDIDVEIKPGDKTDVPDAKGTLKKLVEGKKSTTVFMPVKN
                     KDINYSIQVNEKQEELKDIILYDELPEGLTLINGSVSVVTSDGKEVSDFNIEQSKNSI
                     SVNFGNIDKSYTVKYKARISDKNAKHGNKYKNVARIESDGKKIQEDDATVSIFDRGDD
                     YLLTKGHSGATNITQVGQVINYQISINDDKSPISNVVITDNIPEGMRLTTSGEAGHDF
                     RVVEIPMNGSWTPWSKEKIANNISYKVEEKRNESGQVDKVITGFTINLSKEEVESKFF
                     IAYTLKVISIEDSYINRAVLDANNSEIDKNDEINFKKNSGLISAKKEVDKKVLNSSDN
                     QIVKYKINMSTYGVYDAGQVNLLDEVNSVLEISNIKYSDNLELKKEAGDGKNTIRLVN
                     KYEFKQIKEGEPVQSWVTFDANFTNVKVGETIRNVAQINGSSPPGVETTKQGYAFEAK
                     KVDALDKNVLSGAKFNLEDAFGNIVVKDLVSDEDGIIQSSVKNPGTYYLVEIMAPRGY
                     EKLKDKVKVEIGNEDIGKIVDIGNIENLKQENPPVNPPIPPDTDEPMVNPPVPPSTDK
                     PRKPSSSSDTEDTIVINPPVPPSEDIINPPIPEVLNPPVPPSEEMIETPVKQIIPIPE
                     VVKPSVSEEKNNKVKDDTLVNPPVPPKTGDSTTIIGEILLVIGAIVGLIVLRRNKNTN
                     "
     regulatory      95332..95417
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            95517..96179
                     /gene="zmp1"
                     /locus_tag="PC465_000617"
     CDS             95517..96179
                     /gene="zmp1"
                     /locus_tag="PC465_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease Zmp1"
                     /protein_id="HDF2647948.1"
                     /translation="MRPSKKLLIAIISIFLISSVPVSAHADSTTIQQNKDTLSQIVVF
                     PTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKIKLLSGKLTDEKEYAYLKGVVPKG
                     WEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDSINLELHETAHAIDHIVLNDISKSA
                     QFKQIFAKEGRSLGNVNYLGVYPEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNL
                     AK"
     gene            complement(96301..97263)
                     /locus_tag="PC465_000618"
     CDS             complement(96301..97263)
                     /locus_tag="PC465_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HDF2647949.1"
                     /translation="MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGL
                     VLLPFAVKRLRALSLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSC
                     NPVFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIF
                     SMYTVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILNKNKLHVFANI
                     PIFSGYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVISPILALL
                     ILKEIIPINMVVGILLIVIGSIISIIPTIITQMHNKHVEALYKE"
     gene            complement(97433..98623)
                     /locus_tag="PC465_000619"
     CDS             complement(97433..98623)
                     /locus_tag="PC465_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2647950.1"
                     /translation="MISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPS
                     VEPPETIKAVINDILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTRENLIM
                     TCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLD
                     ALKNAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYR
                     EIIYDGAKVPCVLKYYRNSFIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVA
                     NRILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSLIDMGYSCVKPNGTFYLF
                     PKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKL
                     YNLK"
     gene            98929..99375
                     /locus_tag="PC465_000620"
     CDS             98929..99375
                     /locus_tag="PC465_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2647951.1"
                     /translation="MDFKNLQYESLSYIICNLQKNFKLYCEKCLKPYKLTNGLYFYLI
                     YINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGE
                     EVLGDIKNIFSKWDNHIKKEFSDTEYKELVKNLHVVKDIKTAVEEE"
     gene            99377..100471
                     /locus_tag="PC465_000621"
     CDS             99377..100471
                     /locus_tag="PC465_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="HDF2647952.1"
                     /translation="MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFSDIAKS
                     GVALITLGDVSIRPSFHKVAISLSDEDGVMKYKKIVDEIHNSGAKVSAQLFCSDYDVN
                     LIKDTMKMGITSHDEIKKIMNDGVKDYITNMTKEEIKNIINLFKVTALNAKKAGFDMI
                     QIHGDRLVGSFSSSIFNNRNDEYGGTCDNRSRFASEIISSIRDEVKDIPIDYKFAIRQ
                     ENPHYGNAGVLLSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPTNNHPYFKDEGCF
                     LYLADEVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMVSMSRQLLADSNWLQKVKDG
                     RVDEIKKCCYCNKKCADALQTRSQFGCILD"
     gene            100559..101089
                     /locus_tag="PC465_000622"
     CDS             100559..101089
                     /locus_tag="PC465_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2647953.1"
                     /translation="MKSLVLYSSLTGNTKKIAYTIYDEIQEEKDIKDVNELVDYSIDY
                     ENYDIVFLGYWVDKGICDKNSKQVLENIHNKKIALFGTMGASKKGSYGASIIEKIESI
                     IPKDNEILGSFICQGKIAEGLKAKYKEMLKLSPDNEHIRQQLNNHEESQSHPDEQEIY
                     EASMFAKNMMIKASIV"
     gene            complement(102026..103402)
                     /locus_tag="PC465_000623"
     CDS             complement(102026..103402)
                     /locus_tag="PC465_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647954.1"
                     /translation="MKYKIGFLTTSYFMSDKFKQALKELNDTCEITFIELKGENPFNN
                     LPNIYYEQVDNFDGFVCSGIVPYSELIINIKDIKVPLNFLKLDERDFYKYLFKLLNSQ
                     KDIDFTKSFMDFLREDNNYYDIYSLIDSNKCPYTIKDFNIPQPVYDFKKLNDKLLEIH
                     LDLLRDNKINLSFTRNYIISCELNKLGYDCIYMVPSTESILNTFKSLVNEITLQNLDK
                     NKSATCIVTVNSSEYINEDLIFKNDEIQNQIYNTILNSLSRHGFYGVQVKKNDMKIEI
                     HTTKEMLNNMTNNYTDFFISEDLKEIKYSLNIGWGIGNTNIHAEQNARQANGKSASLN
                     GNCTFIVNDTNDTIGPLYSNKNSNNIEDSSIANKVASFIPLSNTNVSKIMCMINDRNS
                     NNVSAEILADYMNITLRSANRILSILYKAGIATIVNTKLDNQRGRPKKIYKVDFLSFL
                     NKMQKLNS"
     gene            103670..104842
                     /locus_tag="PC465_000624"
     CDS             103670..104842
                     /locus_tag="PC465_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2647955.1"
                     /translation="MNTYLNEISKFVDENREEIVSLWKEIVNMESYTHCKESVNKLAK
                     RLKFEFEKEGLDCELVDVGDNGSTLIGTLGSNINKKPIIFSGHMDTVFETGTFGENPF
                     KIIEGKAYGPGVLDMKGGIIISLYVIKALNKIGYKERPIKMVFSGDEEIGHKDSAGAD
                     VILREAKGGLCAFNMETGLVDNSLCVGRKGRIGCNIHVKGVETHAGNDFEGGRNAIEE
                     MANKILRIQKLTNLDVGTTVSVSVIKGGRVENSIPEDCSIKVDLRFEKVEEMENVKEQ
                     VREICKETYIEGTSTEVNFISEMMPFETTEDVMRFHTFVNEVSKENGFGELNAKRLGG
                     SSDASYLTIANVPTICSFGVRGEWNHTSREYAVVDSMFERVKLISTVILNLDKFEV"
     gene            104856..105503
                     /locus_tag="PC465_000625"
     CDS             104856..105503
                     /locus_tag="PC465_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647956.1"
                     /translation="MDVTAGDNKVTWKGYLSLFVLIVLFSGVFKDSQGFLKALDFANL
                     TGSFGTIADGVDFMGKGGTGAKDGFLFALTLIPTVCFAVGLIDVVESMGGMKAASKIF
                     NPLLRPLLGIPGIAGIAFVSSFTSSDVASIMTKELFESGEITDDERTIFVAYQYAGSA
                     VILNTINTQAPLLPIALLALGPIILIEIFCKILGANLVRLIIGVRNKKNKAKEAV"
     gene            105505..106014
                     /locus_tag="PC465_000626"
     CDS             105505..106014
                     /locus_tag="PC465_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HDF2647957.1"
                     /translation="MSQQNTGNAIVNSKPKKTAVEIFMGGAKKGFYIGVEQILPAMIM
                     GYVIVQFLQLTGLVDILGNIFGPVMGIFGLPGESVVVLIAAFFAKAAGAATAANLFAQ
                     GLITAPQATILIMPCMLMGTLVGHYARIVLVANASTKYRMLLLAVPIFDAIVGMLIVR
                     VLLTVMGLM"
     gene            complement(106387..107499)
                     /locus_tag="PC465_000627"
     CDS             complement(106387..107499)
                     /locus_tag="PC465_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDF2647958.1"
                     /translation="MKISEVATPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHK
                     STYIARLQKNAGASGFLAGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKIN
                     LICATDNIECAKAYSEAFSKSKIECKLLIIVDCGLHRFGVEPEKVVELATEISKLENI
                     KIVGISSHPGQVYGCSSPEGVPDVCVQEDSSMEKAYKALTDNGFNIEIVASGSTPTVE
                     SEAASKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVISKNSSGYYLIDCGSK
                     CLGLDKGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNH
                     SCSTANLTSNLLGFRGDTIEKVIEVDIRENSKQIIL"
     gene            107797..108063
                     /locus_tag="PC465_000628"
     CDS             107797..108063
                     /locus_tag="PC465_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HDF2647959.1"
                     /translation="MNLEPKKLIEQIGKEKDKKDIWIVGGGDIVKLFMKDNLIDDYYI
                     YILPIILGRGISLFKSGIDKTNLNFKKASNIGELVKLEYSKKQK"
     gene            108308..110035
                     /locus_tag="PC465_000629"
     CDS             108308..110035
                     /locus_tag="PC465_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003496244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2647960.1"
                     /translation="MKLILSYLKNYKLLIVLNILAIFSFALVELGIPTIIAKIIDNGI
                     ANQNIAYIKQMGIVIVIISIIGVVGSILLGYCSAKVSTSVTRDIRNDIFEKSQEFSHT
                     EYNKFGISSMITRTTNDAFQIQQFVNILLRTALLTPVMFIISIIMTIRTSVELSIVLA
                     ISVPFIIIGVAIIAKVSQAISSKQQKGLDKLNLISRENLTGIRVIRAFGNDDYETERF
                     EKTNTYYANVSKKLFKLMSITQPAFFLLLNIAVLAVFWISSEKINIGELQVGQLVAFL
                     EYLFHAMFSIMLFSMVFIMYPRAEVSANRIKELLNEEPLIKNPENGIKDTENKGIIEF
                     DNVTFTYPDGEASVLKDISFTAKTGETVAFIGSTGSGKSTLINLIPRFYDVTEGSIKI
                     NGVDIREYDLKALRKKIGFIPQKSLLFTGSIANNIRFGKHKAGESELEYSAKVAQAYE
                     FISKKPRKFDELISEGGANVSGGQKQRLSIARAIIRRPEIYIFDDSFSALDFKTDAIL
                     RAKLKKETKDAIVLIVAQRISSIIDADKIIVLNEGQVVGMGTHKELLKNCEIYYEIAT
                     SQLKKEELE"
     gene            110035..111825
                     /locus_tag="PC465_000630"
     CDS             110035..111825
                     /locus_tag="PC465_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2647961.1"
                     /translation="MKKSKGFKKTIGRLLPFVKKYKFSFIIAIICIISAATMNALAPK
                     TEGLIITQLTKDVISIAKGVPGASVNFDYVTKILVILACIYFANAIFTYTSSFLLTNA
                     IQNTMRDLRNEVENKIRRLPISYFDSNSFGDVLSRISNDVDTISNALQQSFMQIVNSI
                     LVIILALSMMFTINIYMALIALFIIPISYFVSKFVVKKSQSRFSLQQNALGKLNGKVQ
                     EMYTGFNEIKLYGKEEDSIKEFKKVNQELCENGFKAQFISSMMNPMVSLVTYFGIAAV
                     AVVGSIYAVSGGITVGNLQAFVRYIWQINQPLSQMTQLSTVIQSSFAAIERVFEILDE
                     EEEIPDVENPVKIENVKGNVTFEHVNFGYGENSTLIEDLNAEVKSGQMVAIVGPTGAG
                     KTTLINLLMRFYDVKKGAIKIDGVDIRDMKRKDLRSMFGMVLQDTWLFNGTIFENIEY
                     GRFGATKEEIIQAAKVANVHHFITTLPDGYNMFLNEEASNISLGEKQLLTIARAFISD
                     PSILILDEATSSVDTRLELMLQKAMRNLMNGRTSFVIAHRLSTIRNADLILVMNNGSI
                     IEQGNHDELMEKGGFYEKLYNSQFADKESE"
     gene            complement(111987..112295)
                     /locus_tag="PC465_000631"
     CDS             complement(111987..112295)
                     /locus_tag="PC465_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647962.1"
                     /translation="MFNKIYEKKEFIVFQVKKGYVVYNTRKSFEEGHTHLKHFEAAKT
                     AIDLAINKKIPRSKDGYYLTSLIRISDDGYYIDKLSELLYVREQKGKKEKYCNSGYQM
                     "
     gene            complement(112557..113105)
                     /locus_tag="PC465_000632"
     CDS             complement(112557..113105)
                     /locus_tag="PC465_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647963.1"
                     /translation="MIFLNEDVVTNETIDKDYAIEEVRMACKHFGDLYFYFSKVLFEE
                     FGEDKTSEILRKVLFERSEERAIAMRERAHENGDELIADNIISTTDVPFLGWVPEFEE
                     LHCPYGASWLLRFEENPWFKKFASLYCDVTDTTVAEVFTGDTSHKITKNILWGDKSCE
                     RIYFHDDKVSEGKYTYGNKNCK"
     gene            complement(113208..113879)
                     /locus_tag="PC465_000633"
     CDS             complement(113208..113879)
                     /locus_tag="PC465_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2647964.1"
                     /translation="MATFKRLQEQAYDYLKELILSGEMIENEIYSETKLASEIGISRT
                     PIRDALQRLSQDGFIDIIPSKGFRIHQITANEIVEIFQIRSAIEGFCTFLITSQYKEP
                     RAVETISKLKHLLDKQKDILLGDKNLNSFAEYDTLFHTTIVSYAQNTEFDKMFNNYMY
                     RIKKLALDSLSHEGRLETTLKEHTDIFNNIANGCIEDIYRTTLIHMETPKYINLEDFC
                     NNKLF"
     gene            114275..115180
                     /gene="garR"
                     /locus_tag="PC465_000634"
     CDS             114275..115180
                     /gene="garR"
                     /locus_tag="PC465_000634"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HDF2647965.1"
                     /translation="MEGYKMKLGFIGLGIMGKPMAKNLLKDGFNLLVYDINKSAVDEL
                     ISCGAKYASVLEMGQECDIVFTILPNGTIVQDILFGMDGLAKTLKEGSIVVDMSSVTP
                     TESILCANKLKDMGLEFIDSPVSGGEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSS
                     SILIGDNGSGSVTKLTNQVIVNLTIAAVSEAFVLAAKAGADPEKVYKAIRGGLAGSTI
                     LDVKIPMIMNRDFKPGGKISINLKDIKNVMQTAHNLDVPLPMTSQLLEIMQTLKVHGH
                     LEDDHSGIAQYFEKLAGVEIKKHNN"
     gene            115316..116698
                     /locus_tag="PC465_000635"
     CDS             115316..116698
                     /locus_tag="PC465_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF2647966.1"
                     /translation="MITGYGLLIAFVISIGILLVSIIKFKVNPFLALLITSIITGFMV
                     RMPINEISTTISTGFGNTLGSIGIVIGLGIIFGNILSESRATESIAKGLLAKTGEKNS
                     ALAVTTAGFLISIPVFMDAAFVIMMPIIKYVSRVTKKSLMVFVCALGVGTIVGHALVI
                     PTPGPLAVAANVNANVGSFILYSIIVAFPAALIGGWIYGKRFEKYPAYAIDENDREKN
                     LEQGKDSIKIEDDDSSKAPGFGISMFSLLFPILLILISNVFSMFLEKGSTMSGVLAFI
                     GDKNIAILLGILVAIGFLKKYINKPMGDVVIEAADSAGLILLITGSGGAFGSVINASG
                     IGNFLVDTMSGLSISVVVLGFLLSALLRISQGSATVALVTTSSILGPTILATGMSPVL
                     VGLAICAGGVGFSLPNDSGFWVLSRFSGLSVKDTLNSWTIGGTIAGVVAFIMILLLSV
                     INGIIPLPGL"
     gene            116769..118205
                     /locus_tag="PC465_000636"
     CDS             116769..118205
                     /locus_tag="PC465_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HDF2647967.1"
                     /translation="MREVKPISIDILNTFKQVDEDRLNKLLADELKHLDRKIVVLDDD
                     PTGVQTVHDISVYTDWDKDSMEQGFNEKNSMFFILTNSRGFTVAQTTKAHKEISKNIV
                     DVSKKVNKDFIIISRSDSTMRGHYPLETNLLKSEVERLSGKLFQGEIIMPFFKEGGRF
                     TIDNVHYVKEGEILVPAGMTEFAKDKSFGYKSSDIGEWCEEKTNGKYKSSDMIYISSK
                     ELRELNIEAITEKLKKAEGFNKIIVNATDYVDVKVFTIAFIRAVNSGKEFMFRSAAAI
                     TKVLGGVSDKELLTKDELVSKGNTNGGIILVGSHVNKTTQQLEELKNCKYPIEFIEFN
                     QHLVLQENGLKNEVKRVIKVVEEKISRGKTVAVYTRRERFDLDTNDKDKQLMISVEIS
                     DAVTSIIGMLNVRPNFIIAKGGITSSDVGTKALRVKKATVMGQIKPGIPVWMTGKESK
                     FPNMPYIIFPGNVGEISTLRESVEILMG"
     gene            complement(118391..119245)
                     /locus_tag="PC465_000637"
     CDS             complement(118391..119245)
                     /locus_tag="PC465_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647968.1"
                     /translation="MSTFYIQFLYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFC
                     PIYGFGALAIVATLTPFVHNIPLLFLFSIIITSIMEYCTSFILEKIFNMTWWDYSKHK
                     FNIHGRVCLENSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEIYFVLDLV
                     ITVHTILQLNGKLKQINLIIKELKDKKEYYKLITQETIENKLESLVENRLDTLEDRFE
                     ILKEKENYRYAKNRIDELKNKLNTLLSNHKLLHRRIIKAFPNISSNKHTDILNKIKEN
                     IKSIKKDK"
     gene            complement(119513..119836)
                     /locus_tag="PC465_000638"
     CDS             complement(119513..119836)
                     /locus_tag="PC465_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HDF2647969.1"
                     /translation="MERINCNVINCSHNNSHICYADKIFINGEKAHNDRHTCCSSFLD
                     ESIYSNLSSNVNNRNCEELVCTVKNCKYNKDGSLCTLDNILVAPETDRVNLYIETCCS
                     SFECK"
     gene            120039..120668
                     /locus_tag="PC465_000639"
     CDS             120039..120668
                     /locus_tag="PC465_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647970.1"
                     /translation="MFEKKKKELFPWKISALILVGVFVLSSGVYIGTRLKHNGVQTGE
                     VVSTSANMNEKSKEAFGLNKNCEVWLQSEGENETNYKRTLTMAGIVPESLLDKTKSEI
                     VSYFKKEYPTKKIKSMDKNEIILVESKYSDNKDVQAMDVTIKGKYTIENDNGNIALYK
                     YDDSGTKTLVEKTKIRVDSLPKTVQDEIKKGVVMDTEEEAYSRLEDFAS"
     gene            120996..121505
                     /gene="ruvC"
                     /locus_tag="PC465_000640"
     CDS             120996..121505
                     /gene="ruvC"
                     /locus_tag="PC465_000640"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HDF2647971.1"
                     /translation="MIILGIDPGIAIVGYGIIEYKNSKFKVIDYGAVTTPAHMNISRR
                     LELVYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEY
                     TPLQVKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNKLEKT
                     LKNIGGKYV"
     gene            121498..122100
                     /gene="ruvA"
                     /locus_tag="PC465_000641"
     CDS             121498..122100
                     /gene="ruvA"
                     /locus_tag="PC465_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HDF2647972.1"
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEAT
                     KIYTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASPAQLGAYIL
                     SEDIGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALV
                     ALGYTLSESKEAVQKCKKDGMNTEAIIKKALTYIMSKSLK"
     gene            122207..123226
                     /gene="ruvB"
                     /locus_tag="PC465_000642"
     CDS             122207..123226
                     /gene="ruvB"
                     /locus_tag="PC465_000642"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HDF2647973.1"
                     /translation="MQGFEDENRIITSTMKMEDIDIENSLRPKTLEDYLGQEKSKEQL
                     SIFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAA
                     ILTNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTL
                     IGATTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSSILDAEIQSNGALELAKR
                     SRGTPRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTII
                     EKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIP
                     YPNEK"
     gene            123544..124569
                     /gene="queA"
                     /locus_tag="PC465_000643"
     CDS             123544..124569
                     /gene="queA"
                     /locus_tag="PC465_000643"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HDF2647974.1"
                     /translation="MKTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFR
                     DIIEYLNPGDCLVLNNTRVIPARLIGEKLETGGKIEFLLLKRTEEDTWQALVKPGKRA
                     KVGTKFSFGNGKLIGEVVDLSDEGSRIIKFHYDGIFEEILDELGNMPLPPYITARLDE
                     KERYQTVYSKHNGSAAAPTAGLHFTEELLNKIKEKGVDIAFVTLHVGLGTFRPVKVED
                     VLNHKMHSEYYMVSQEAADKINRAKENGKNVICVGTTSCRTIESACNEDGKMKETSGW
                     TEIFIYPGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSF
                     GDAMIIK"
     gene            124581..125066
                     /locus_tag="PC465_000644"
     CDS             124581..125066
                     /locus_tag="PC465_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647975.1"
                     /translation="MHSLQKQKKNNPILKIAFIFERVLAVVVLIAVFLGTIDVLRLMW
                     GAYIVDFQNPVQYSQLNDFLAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLL
                     LPKNEGMIDVLIGVIAIAGLFAIKKFLVTKDKSALNIMSIHDEEAIKEQQNKEDEDKS
                     I"
     gene            125145..126266
                     /gene="tgt"
                     /locus_tag="PC465_000645"
     CDS             125145..126266
                     /gene="tgt"
                     /locus_tag="PC465_000645"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HDF2647976.1"
                     /translation="MYAVRYELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVK
                     SMTPEELKEIGSQIILSNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFS
                     LGPLRKIKEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYV
                     KNSLERTTRWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITNIDLPGYAIGG
                     LSVGEPKPLMYDVLEHTTPLMPKDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIA
                     RNGTAMTSQGKVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLI
                     TTHNLHFLLNLMKQIRQAIMEDRLLDFRNEFFAKYGYEI"
     gene            126400..126693
                     /gene="yajC"
                     /locus_tag="PC465_000646"
     CDS             126400..126693
                     /gene="yajC"
                     /locus_tag="PC465_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HDF2647977.1"
                     /translation="MPQQQIIMSIGLWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLSV
                     GDKVITIGGIVANVAKVEDDVVILELGPNRTKVPFEKWAIGTVKSKKEEIEED"
     gene            126751..127113
                     /locus_tag="PC465_000647"
     CDS             126751..127113
                     /locus_tag="PC465_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04086 family membrane protein"
                     /protein_id="HDF2647978.1"
                     /translation="MGKSNYIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSS
                     FITTISAAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEIGMIYKL
                     LLISAAGGIGGVLGVNFK"
     gene            127179..127322
                     /gene="scfA"
                     /locus_tag="PC465_000648"
     CDS             127179..127322
                     /gene="scfA"
                     /locus_tag="PC465_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="HDF2647979.1"
                     /translation="MENKHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQE
                     CER"
BASE COUNT        48669 a        14701 c        22007 g        42122 t
ORIGIN      
        1 tataaacgtt aaaaaaataa cgttatcctt aagtttttag atgatttcat tagtgatttg
       61 cgtaaaaaat aaagtgatat ctagttaaat taagtatttg taaagctaga tattattagt
      121 agaaatggtg ttatattaga taaaaaataa aatgttaaaa aaataacttg aaaatagaaa
      181 aagtaaatgc tataatgtta ataaattaac atgataaata aaaaactatc tcaggaggtt
      241 gttaaaatgg ctcataaaga acaagtaata atagaaaata aaaaagaaaa tgaagttatg
      301 tcagttggtt tagatactgt aaataacgtt gaaagcttag ttaaaaaact agcaaaaatc
      361 agagaagctc aaaaaatatt tgctacatat agtcaagagc aggtagataa aattttttta
      421 gcagcatctt tggcagctaa taagcaaaga gttcctctag ctataatggc acaaaaagaa
      481 actggtatgg gaattgctga agataaggtt ataaagaatc attatgcctc agagtatata
      541 tataatgcat ataaagaaac taaaacttgt ggtgttatag agaaagacga agcatttggt
      601 atgactaaaa ttgctgagcc aataggtgtt attgcagcag ttgtacctac aactaatcca
      661 acttctactg ctatctttaa agcactttta gctttaaaaa ctagaaatgg aataattttc
      721 tctccacatc caagagcaaa aaattctact atagaggctg caaaagttgt tcttgaggct
      781 gctgttttag ctggagctcc tgaaggtata ataggatgga tagatgagcc atctttagaa
      841 ttaactacaa ctgttatgaa agaagtggat ttgacccttg ctacaggagg tcctggaatg
      901 gttaaatcag cgtattcatc tggaaaacca gctattggag ttggtgcagg taatactcca
      961 gcaataattg atgatagtgc agatataaaa actgctgtaa actcaattct tgtatctaag
     1021 acttttgaca atggtatgat atgtgcttct gaacaatcgg ttatagtatt agaaaatata
     1081 tacaatgaag tcaaaaaaga atttaaagag cgtggtgctt atttattaga taaagatgaa
     1141 acagaaaaaa taagaaatat aattttagta aatggaggat taaattctaa aatagttggg
     1201 caaacagctt gtactatagc aaaacttgca ggctttgaag tcccagtaga tactaaggtt
     1261 ttaataggtg aagtagaatc agttgaaata gaagaagctt ttgctcatga gaaactttca
     1321 ccagtacttg caatgtacaa ggcaagtgat tttgatgatg cagttagaaa agcagaaaaa
     1381 ttagtagaag atggtggatt tgggcataca tcttcattat atattgatga tgtaaatcaa
     1441 agagaaaaac ttgataagtt tacttcagcc atgaaaactt gtagaatttt aattaatact
     1501 ccttcttctc aaggtggtat aggggactta tataatttta aactagctcc ttctcttact
     1561 ttaggatgtg ggtcttgggg tggaaattca gtatctgaaa atgtaggagt taagcattta
     1621 cttaatatta aaacagtagc tgagaggaga gaaaatatgc tttggtttag agcaccagaa
     1681 aaagtttatt tcaaaaaagg ttgtttagga gtagcattaa aagaacttaa agatgtaatg
     1741 aataagaaga gagcttttat tgtaacagat acattccttt acaataatgg atatactaaa
     1801 gcagttactg atttattaga tgaaatgaat attaagcaca ctacattctt tgaagtagaa
     1861 ccagacccaa ctttggaatg tgctaagata ggcgctaaag ctatgagaga atttaatcca
     1921 gatgtaataa tatctatagg tggaggaagt gcaatggatg caggaaaaat aatgtggaca
     1981 ttgtatgagc atccagatgt agatttccaa gacctagcta tgagatttat ggatataaga
     2041 aaaagggtat atacattccc taaaatgggt gaaaaagcta attttgtagc tataccaaca
     2101 tcagcaggta ctggttcaga agtaacacca tttgctgtta taactgacca agatacagga
     2161 gtaaaatatc cattagcaga ttatgaactg atgccaaata tggctatagt tgattctgat
     2221 atgatgatga atatgccaaa aagcttaaca tctgcttctg gtatagatgc tttaactcat
     2281 gcattagaag catatgtatc tatgcttgca accgattata caaatggatt agcgttacaa
     2341 gctattaaga gtatatttga atatcttcca cgtgcatatg ataatggtgc aaaagaccca
     2401 gaagctagag aaaaaatggc aaatgcttct acaatggcag gtatggcttt tgcaaatgca
     2461 tttttgggtg tttgtcactc tatggctcat aaattaggtg ctttccacca tgtaccacat
     2521 ggtgttgcaa atgctctttt gataacagaa gttatgaaat ttaattcttc agatgcacca
     2581 aagaaaatgg gagcattctc tcaatataaa tatccagaag cattaaagag atatgctgaa
     2641 atagcttcat ttttaggatt aaaaggaaat tctgatgaag agaaattcca aagtttattg
     2701 gtagctattg aagatttaaa acttaaagtt ggtattccta aatctataaa agagtttggc
     2761 gttgaagaat ctaagtttat ggattcaata gatgaaatgg taattcaagc atttgatgac
     2821 caatgtacag gagcaaatcc aagatatcca cttatgaatg aaataaaaga tatgtattta
     2881 aattcatatt atggaagata agtttgctat aaaatagata aaataaaaac tcttatacat
     2941 aaaacaaagt tttattgtat aagagttttt ttgtttgaga aaatggatag tttttattct
     3001 ttaatttaaa attcaattaa atagtgttat tataataata aaagaatgtt tttatggtta
     3061 ttatgttgat tttatgtgta acatttaaga atagttatat acaatataaa tgatgaattg
     3121 gtataaaaag gatatattat ctatatgaag tattgactaa ttaggggagg agtcgaatga
     3181 cagggagaaa taaaagtttt acattaatta caattctttt tttaacatca ttatttttga
     3241 caatggggta tatctatata gaagatacaa aacatcttct tatgtcagag gcaaaaatac
     3301 atataaaaga agttgcagta caaggctctc aactagcaca aagacaaatt gaaaaagatt
     3361 tagatgtttt aaatattttt tctaactatt atgcttcaaa tccagatata cctaatgagg
     3421 aaaaaatgaa aaatctttta gatgaaatgg aaaatcaaaa attttacact atggcaatag
     3481 ttgatataaa tggtaatgct gaaaatacca aaggtgataa gttttcagtg aaagatagag
     3541 aatttttcaa aaactcaatt aaaggtaaga agtatgtttc aagtccatat gttgatgaag
     3601 taaataagtc tataaagaag attgctattt cagtaccatt attaaataat gataaagtag
     3661 ttggagtttt atattgtact tacaatatca atactctgat gaaacttatt aatatatctt
     3721 tttatgaaaa taatagtata tcttatgttg taaaaaataa tggtacaatt atccttcatc
     3781 cacaagggga tagcctatca aaaaatattt ataaattgtt aaaacaggat aatgatattc
     3841 aagaagtaaa tagattaaaa aaagaattgc aagaaaataa aacaggtgca actgtattaa
     3901 atatgttgga agaaagaaga tatttaggat atgccactat ggataatggg aatagtgaaa
     3961 ataattatat aaaagactgg aatttaattt tttcaattcc agaaactgtt gtatttagta
     4021 attcaaaaca aataatcaac agagctgtat atgcagtgtt atctattgta ttaatattta
     4081 ttgcaattat tttttatata atttatataa aaaaatctaa tgaaaaagaa atattaagtt
     4141 tggcttatga agataaagtt acatatatag gaaatcaaaa taaattttat agagaatgta
     4201 gtaagtatct tttagataaa ccatctttaa attatattat agtatatttt gatattaata
     4261 actttaagat gattaatgat acttttggat atgaatttgg tgacaattta ttaattacaa
     4321 tagcaaaagc tttaaaagaa gaattaacag aaggtgaggt atatgcacga ctttcaagtg
     4381 attattttgc aattttctgt gattataaaa atggaagaaa taaaattata agaaaacttg
     4441 ataatatacg aagtaatatt gaaagtaatt tgagtatagt ctttgaaatt tctctgtgtg
     4501 tgggtattta ttttgttgaa gaaggtgaag tagatattca aaaggctgta aataaagcaa
     4561 atatggctag gtctgttgct aaaggtaaaa atataaatta tgctatttat aatgaagatg
     4621 ttaggaataa gcttagtgag gaatcaatga ttttagatga tataaaaata gcattggtaa
     4681 aaaatcaatt tgaagtgtat tatcaaccta agttttcact tgtaactgga gaaatgatag
     4741 ggagtgaagc actaataaga tggaatcatc cagaacatgg ttttataagt cccgcagtat
     4801 ttattccaat agcagagaaa agtaagttga ttttaaaaat tgggagattt gtatttgaaa
     4861 gggtttgcaa tgatttatat gaatggaaaa agcaaggtaa aaagatagtt ccagtttcag
     4921 taaatttatc tagggtcgag ttgtatcaac cagatattgt aaaatttatc aataaaacaa
     4981 taaaaatgta taatttaagt tcagatttca ttgaaataga gataacagaa actgtggcta
     5041 ttaatgagtt aaatatttta aagaatgttt taaatgagtt gaggacgtat ggattttcta
     5101 tttctatgga tgactttggt acaggatatt cttctattag ttgtttaaga gatatgccaa
     5161 ttgatatatt gaagctagat aagtcttttc ttggtggcat tgaacatgat gagagaagtc
     5221 gcaatatagc aaaatcaata gtgtctctag caaaatccct agatttagtt gtaattatag
     5281 aaggtgttga gagtaaagaa caagctgagt taatgaaaca atttggatgt gatttagttc
     5341 aaggatttta ttttgcacga ccaatgccag ctaagaattt tttagattta ctttaaaaca
     5401 aaatttgatt tttatataaa gcactattat gaatgcttga ttttaataaa tcattgctaa
     5461 ataattagtg tttttttatt ttatcaatgt attgtctaat ataaagcaaa aaataattgt
     5521 attttataaa aattatatta aaaataaatt tattttgcta ataaacatgt tattaacaaa
     5581 agaatagtac tataatgtat agatgataaa aactttaata aaaatttagt gtataggagt
     5641 tgtttaagta tgatagatat aagtattgat gacaaactta aggaaagatg gcctaatgct
     5701 aagctgggtt gcattcaagc aaaagtagca gtaaataaaa gctcagaaaa attaattaat
     5761 gaaataaatg agttttgtga tactataaat caaagtctaa aagttgaaga cattacgaaa
     5821 ctagataaaa ttaaagatgc aagaaatgct tataaagagc ttggaaaaaa tccaagtaga
     5881 tatagaacat cttcagaagc attggttaga agaattattc aagggaaggg tctttataca
     5941 ataaataata tagtagaaat aaacaattta atatcaataa aatcattata tccagtaggt
     6001 acatataatg taagcaaatt acattcacca gtatgtttta ctgtaggaga tgaaggagaa
     6061 cagtataagg gtattgggaa agaattaata aatatagaaa atcttcctat attgtctgat
     6121 tcagtgggta aatttgggag tccaactagt gattctgaaa gagcaatgat aacagaagat
     6181 gcaaatgaaa tattaatttg tatattttct tttagtcaag aatctgatat tgaagaatat
     6241 tttggatatg ctaaggaatt acttaaagaa tatgcagatg gaaaagatat agaaactaaa
     6301 ataattaaat agaatctata taacaacgtt atgttaagct aaaattcaat ataaaaataa
     6361 gttaagataa agaaactaac acaaaattag tttctttttt aaaatagtag tttagtgtta
     6421 caaaaataga tagatagtcc cacgattatt aaaagtatgg taatatatta atatagcaga
     6481 gattgtgttt aagggatttt gaaagggggg atttataata atcattttat ctaaaagata
     6541 aaatggtttt atagaaataa ctatatattt aaaaatataa ataatgatac agtaatttgg
     6601 gtatataaaa taaggcatac atggttttgt ttaaaaacca ataaggtaca taggtaatta
     6661 caatgtaagg aaggatttaa ttatgattga tggaaaagag gtaaaacaag aaagtggaca
     6721 aaaaaatcta aaatttaaga tagctatagt agtaggtgtt ttgtttgtag cttatatagg
     6781 aatggcaatc ttttttagaa atcattttta ctttggaacg actattaatg gcgtaaaggc
     6841 ttcaggaaaa acagttgagc aagtaaatga tttgttagca tctagtacta attcctatac
     6901 tttaaactta gaggaaagaa acaataagaa agaacaaata aaagcaaaag atattgattt
     6961 aaaatttaca ccagatgata aagttcaaaa gataaaagat agtcagagcg ctattggatg
     7021 gattggtgga atatttaaat ctaaagagta taataatatg ataactcttt catataataa
     7081 agatttacta gaaaaaaggt ttaatgcttt atcttgtttt gatagtaaaa atgttgtaga
     7141 acctaagagt gcttatccta agtatgatag cactaaaaac gcttatgtta tagtaccaga
     7201 ggtacttgga aacaaagtga aaaaagatga tttttataag ttagtacaaa actcaattaa
     7261 ttctgggaat acttctattt ctctggatga aagtaaagtt tatgaagcac caaacaacac
     7321 aaaggattca gaaaagttga aacaagctat taagacatta gataagtatg ttggtgtagt
     7381 cgttacatat gattttagtg accgtaagga aactttagat ggttctgaaa ttaataaatg
     7441 gttaaaagta gactcagaaa agaattatga cataactttt gataatgatg ctatggtaga
     7501 atatacaaga ggtttaagta aaaaatacag tacttttggt gactcaagac catttaaaac
     7561 tgccacaggt aaagatatta caatttcagg tggaatttat ggttggttga tagataaaaa
     7621 gaaagaagct gaagcattag ttgatgttgt aaaagctggt aaaaatgtta caagagaacc
     7681 tatttacata caaaaagctg tatctcgtaa taaagatgat attggaaata catatgtaga
     7741 gattagtctt tctggccaac atatgtggtt ctttaaaaat ggagaaatgc ttgtatcaac
     7801 agacgttgta acaggtgatt tagctagagg atttgctaca ccatcaggta tatatcctct
     7861 taattataag gctagaaatg tttcattaac tggtcaaggt tacagttcac ctgtaagtta
     7921 ttggcttcca tttaatggga acataggcat tcatgatgct acttggagaa attcttttgg
     7981 tggaagtata tataagtctt caggttcaca tggatgtgta aatacacctt tttctaaggc
     8041 aaagaaaata tatgaaaata tagaaccagg tacaccaatt attttatact agtaaatgtg
     8101 ttgctaacag ttaagcgaag tcatcttagt ttatttagga tggcttcctt tttatataaa
     8161 gcttattgaa gtttacagaa agactactta aaaggagaaa tacataatga atgaaaaatt
     8221 aactaaaatt ttagaagaag ctaagaatga tgatgaattt agaaaggaac ttataaaaac
     8281 aagagaacaa cgtgatgtta tggattcatt ttgtaaggtt gttacatcta gaggttatga
     8341 tatgacagta ggggaacttt tttctatggg agaagaatat acatccaatc tactgaaaag
     8401 tgtaaatgga ggagcagcat atcctattga agattggagt gattggtacg aggatttttt
     8461 tataatgttg tcgaatatat agagtaacta atgatattat ctacttaaga ttaatacatt
     8521 gccttaaaat aaaactatta gaactaggtg taagttttat caatctttaa aaatattgat
     8581 ttatttctaa ctagatataa aaaaattaga ttaaaaataa ggtgacaaaa atcgatatag
     8641 cttgatgatt tataaaagtt agataaaata gtgcgagata tttctaaaaa ttcaaaaaaa
     8701 acaataaact tcaatggtta gaggttgaaa aagaatataa aaaactttta tatgtaataa
     8761 attaaattaa aattataaaa aaaataaaat aaaaatttaa aatgtcgaca taacgttaat
     8821 tttaaaacaa aataacgcta ttgacaaact atatcgcttt aaattataat tattgaaaat
     8881 aatggtattt aaaaaccata ctcatgtcat agtctaaaag taagtcaaaa aaggatgtaa
     8941 atctaggcaa gtactattct aaaatatgtt ttattaagaa ataaacgttg aaaaatatta
     9001 attattatat aaaaatgctg tttatacttt aacaatgagg tagtaatcta attagaataa
     9061 aaaaatctaa ttggttatat acatagtaaa aaggtaagag aggtgatttg gatggctttt
     9121 gaaataataa aaagcattgt tgaggcagag cagacagcag acagtatcaa agtaaaagct
     9181 gttactgatg cagagtctat cagagctgat gctgtaaaca aatgtgaaag catatttgct
     9241 gatgtaaaaa aacaagcaaa gcttatggaa gaaactctta ttgagaaggc agtcaccgac
     9301 agtagagcag aggttgataa aatcttagct aatgctaaaa gtgaatgtct gaaaattgaa
     9361 aaaactgctg aagaaagaaa aagtaaggct attgaagcgg ttattggaaa ggtagtgaga
     9421 taatatggca atagttaata tgaacaaaat atctattgtt ggcttagaag ctcaaaaaag
     9481 ccagatttta aagctactta tgaaccgtgg gtttgttcag attgatgata gtgcctttct
     9541 tactgaggag gaggaattaa aaaattatct tgtaaaagat agtgaagaat ctgaagttat
     9601 aatgctagag cagaaaatgt ctcatgtaaa ccaagcaatt aatattgttt cttcactagt
     9661 gaaacaaaaa aaatccctac ttgcaccaaa aagagagttt aacaaaattg atagtgaaaa
     9721 agaagggcaa gtttatgctg aagctctgga gttaaacaat ttgcacaagg agataggtac
     9781 aataaggtct aacataaact tacttaacaa caataaaagt atgttagaac catgggtgaa
     9841 ctttgatatt cctattgaaa atatggaaac taagtataca aaaactatac ttggaactgt
     9901 gcccataagc gcaaacattg atgctttaag agtaaaatta gaagatgaaa taccagaaag
     9961 tgttattggg attgtcaatt ctgacaagtt aatgaactat gtttatttaa ttactttaaa
    10021 agaaactttt gatgatgttt tagaagtttt aaaagaattt aatttttcag tggtttcatt
    10081 accaaatgaa gaaggtacac cgttacaagc tatcaagaaa tacaatgaaa tgataattag
    10141 acaggaaaac gtttctaagg acaaaacaga ggaaattaaa agacatgcag atagtataca
    10201 catgcttgaa aacctatatg atttttacac tatagaaaga gaccaaaaaa agattataga
    10261 gagacttgtc aaaacaaaaa caacattctg tcttaatggt tggttaccaa gcaaaagggc
    10321 agatgaatta attaaagaaa ttacagaaaa gtttgattgt tgtgttcaga ctgaagaagg
    10381 aagtaaagaa gaaggcttcc caattctgct tgaaaacaat aaattagtaa caccttttga
    10441 aagtgtaact aacatgtaca gctatccaag tacaaaagat attgacccaa atacaatttt
    10501 aactttcttc tttgttgtat tctttggaat gatgctaagt gacgccgcat atgggttaat
    10561 aattgcagta gtttgtggat ttgttgtata taaattaaag atacaaaaag gtgaaggaaa
    10621 tttaattaaa cttattggta tctgtggagt ttcaactact gtatggggtc ttatattcgg
    10681 gggtattttg ggggatttaa ttcctataaa agcattaatt aatcctttag aggatgttat
    10741 gacacttatg ggaatgtcgt tactgttcgg tattatccat atatatgtag gtttgggaat
    10801 aaaagcatat acattaataa gaagtggaaa ggtaatagat gcaatctttg acataggttt
    10861 ttggtatttg tgtataacag gtgtatgtct acttataata ccttttgttg caggggacat
    10921 aggtgtattt tcagaagtag gaaaatattt agcaattata ggtgctatag gtcttgtact
    10981 tactcaagga agaagcttta aaggtattcc tgttaagctt tttaaaggat tttcaagtct
    11041 ctatggtata acaagttatt ttgctgatat attatcttat acaagaatta tggcgctttg
    11101 tttaacaaca ggagttatag cacaagttat caacctttta ggagctatag ctggtccgat
    11161 acttgcagtt gtaattggtg ttgtaggaca cacaataaac cttcttataa atgcactagg
    11221 tgcatatgtt catacaagta ggttacagta tgtagaattt ttcaataagt tttatgaagg
    11281 cggaggagtt ccttttgttc cgtttaagta taaaacaaaa tatacaagca ttaataaaaa
    11341 ggagatgtaa atatggaatt tttaaacgcg ttaggaaatg gtcaattttt ggcaatatca
    11401 ggagctgcta tagcagcatt atttgcaggt atgggttctg ctaaaggtac ttcaatagca
    11461 ggtcaagccg cagcaggtgt tgtaacagaa gaccctagta aattcggtca acttctagtt
    11521 ttacaacttc ttcctggtac acaaggtctg tatggattta tcatagcttt ccttatttta
    11581 tcaaaagcag ggattattgg tggagatgca ataccaacat cagctcaagg tttacaactt
    11641 cttatggcag gacttccaat tggtttagtt ggtttagtat caggtatagc acaaggtaaa
    11701 gcagcagcag caggagttgg aatagttgca aaaagacctg aagaacttgg taaagctata
    11761 acatttgcag caatagttga aacatatgct cttttaggac tacttgtttc tttcttagct
    11821 tacaatggaa ttgcaattgg ttaattataa attataattc ataagtaaaa aaaatgaaaa
    11881 ggaggaagca ctcctatggg taatgaacaa aaaatgattg acagaattat agctgatgcc
    11941 aaacaagaag cacaagaaat attggataaa gctaaaagtg aagcagattt aaaagtaaat
    12001 tcagctaatg aaaaagctga aaaggaaatg gcttcctata caaagcttgc agaggcagaa
    12061 gcagaaaaag cggcttctaa ggaaatatca ggagcttata tggaggctaa aaagcaaata
    12121 ttatcaaaaa aacaagagat tttagaagag gtaattttag aagctaaaaa caaactttta
    12181 aatcttaaag ataatgaata tgaagagatt atactaaaca tgattgaaaa atcaaattgt
    12241 acagatgatt cagagatagt attatctaaa aaagataaaa aaacattaaa agatgtgcta
    12301 tcaaaaaaag gcattaaagt gtctgatgaa actagagata ttactggagg tttcatagtt
    12361 aaaaaaggtg acattgagta caattattca tttgaagcca taattgcagt agagcatgaa
    12421 tatattgaac aaattgcagc agaaattttg tttaattaag gaggggttaa aaaatggcag
    12481 aagaaaaaac ttatccctat gccgttgcac gaataagagt gcttgaaaaa cagcttctta
    12541 acagacaaat gtttattcaa atggcagaag ccaaaagccc tgaagactct ttaagaatta
    12601 tagctgaggc aggttatgct gatacatcaa ataataatat acataatttt gagaatattt
    12661 tgactcaaga attatcaaag acatatgaaa ttcttaaaag tctagctcct gaagaaaaat
    12721 ttgttgatgt atttctttat aaaaatgact atcacaattt aaaagtgctg attaaagaag
    12781 aaatttctgg tgtagatggt gagaaatatt taattgatgg aggtacaatt cctcttatta
    12841 agcttagaga atctttagca aatcgtagtt ttagtgattt acctaagata atgtcatcag
    12901 ctatattaga ggcatttgat gtttataata agacacaaaa tggccagatg gttgatattg
    12961 ttctagataa agcaaccttt accagtatga aagaaactgc taaagaaagc caaaacaaat
    13021 ttgtaataga ttatgttatg aaagtttgtg atttaacaaa tctaaagagt tttataagag
    13081 tcaaaaatat gaagaaagat tttgatatgt ttatgaatgt gtttgtttca ggtggctcac
    13141 ttgataagga aaaattctta gaagcttttt cctcagatac tccagcatca tgttttaaat
    13201 ctacttctta ctctgatgtc tgtaaaaatg gcatggatag tggttttact gtctttgaaa
    13261 aactttgtga tgactatctt atggaatatg ttagaggagc aaaatttaag cctcttacat
    13321 tagaaccact aattgcatat ttatatgcta aagaatcaga gataaaaaca attagaatta
    13381 ttttgactag taagcttaat aatatagacg cagatactat aaaagaaagg ctaagggatg
    13441 cttatgtata aggtaggagt agttggagat aaagatagca tcatgggatt tttagctctt
    13501 ggaatagata tcttcccagc ctatgatagt gacgaaatta aaaaaagtat acataagttg
    13561 gttgaagatg aatatgcgat aatttatatt acagaacagg catcattgct tgcaaaagaa
    13621 tcaatagcaa aatacaaaga ttaccaactt cctgccatta tagttattcc aggtattgga
    13681 ggaagtatgg gattaggtat gaatgaagta agagaatcta gtaaacgtgc tataggtgca
    13741 gatatattat ttaaagaata gatgaaagtt gaataaaaga caatctcaaa ttttattggt
    13801 gctaaatata tgtgctaata aaatatagga gggaatattt aaattttgat aaagtatatg
    13861 attgcaggtg agagaatatg aaaacaggca caattgtaaa ggtgtcagga ccgcttgttg
    13921 tagcggaggg catgagagat gcgaatatgt ttgacgtcgt aagagtttca gataaacatc
    13981 ttataggcga gattatagaa atgcatggag ataaagcttc tatacaggtt tatgaggaaa
    14041 cttccggtct aggaccaggg gaagaagtag tttctcttgg aatgcctatg agtgttgaac
    14101 ttggaccagg tcttatttca actatttatg atggtattca acgtccactt gaaaaaatgt
    14161 atgatatttc aggtactaat ataactaaag gtgttgaagt atcttcactt gatagaacaa
    14221 ctaagtggga atttaaacct aaaaaatctg ttggtgataa ggttgtagca ggagatataa
    14281 ttggtggcgt tcaagaaaca gcagtagtag aatgtaaaat tatggttcct tatggagtta
    14341 agggtactat aaaagaaata tattctggtg aatttactgt tgaagataca gtttgtgtta
    14401 ttacagatga aaaaggtaat gatatacctg taactatgat gcaaaaatgg ccagttagaa
    14461 aagaaagacc atatagagaa aagaaaacac cagattcact tcttgttaca ggtcaaagag
    14521 ttatagatac atttttccca atcacaaaag gtggggtagc agctataccg ggaccttttg
    14581 gaagtggaaa aactgttaca cagcatcagc ttgctaaatg ggcagatgca gatatagttg
    14641 tatatatagg ctgtggcgag cgtggaaatg aaatgacaga tgttcttctt gaatttcctg
    14701 aattaaaaga cccaagaaca ggcgagtcac ttatgcaaag aactgtgctt atagcaaata
    14761 catcagatat gccggttgct gcacgtgaag cttctatata cactggtatt acaatagctg
    14821 aatattttag agatatggga tatagtgttg cacttatggc agactctaca tcaagatggg
    14881 ctgaggctct tagagagatg agtggtcgtt tagaggagat gcctggtgaa gaaggttatc
    14941 ctgcatactt aggttcacgt cttgctcaat tctatgagag agcaggaaag gtaaattgtc
    15001 taggtatgga tgaaagagaa ggaacactta cagcaattgg tgcagtttct cctcctggtg
    15061 gtgatacatc agaacctgtc agccaagcaa ctcttcgtat agtaaaagta ttctggggtc
    15121 ttgatgcatc tttagcatat aaacgtcatt tcccagcaat taactggttg actagttatt
    15181 cactctatca ggaaaaagtt gatgtatggg cagataaaaa tgtaaatgat aatttctcag
    15241 ctcaaagagc tcaagctatg aaacttttac aagttgaatc tgaacttcaa gaaatagttc
    15301 aattggttgg tgttgattca ctttcagatg gagatagatt gatactagag gttactcgtt
    15361 ctataagaga agacttcctt catcaaaact ctttccatga agttgatact tatacatcac
    15421 ttcataaaca atatagaatg atgggactta tattaaaatt ctataagtca gcacaagatg
    15481 ctatcaagca aaatgttact ataaacgata ttatcaagct ttcagttctt gaaaagattg
    15541 gtcgtgctaa gtatgtagaa gaaggcgata tagatgcagc ttacgattca attgaagatg
    15601 aaatagacaa cgagcttgca gaccttatta aaaagagggg ggctgaagaa ctatgataaa
    15661 ggaatataag tcaatacaag aggtagccgg tcctcttatg ttaataaacg gcgtagaagg
    15721 tgtaaaattt gatgaacttg gagaaattga actttcaaat ggagaaattc gccgttgcaa
    15781 agttctagag gtaaatggag atactgcact tgttcagctt ttcgaaagct caacaggtat
    15841 aaaccttgct gaaagtaaag ttcgtttttt aggaaagagt cttgactttg gagtttcacc
    15901 agatatatta ggtcgtgttt ttagtggaat gggtagacct attgatggag gtccagaaat
    15961 tataccagat aaaagacttg atataaatgg agctccaata aatccagcag cacgtgatta
    16021 tccggccgag tttatacaaa ctggagtctc tgctatagat ggacttaata cattggttag
    16081 agggcaaaaa cttcctatat tctcagggtc tggtttgcca catgccaatc ttgcagttca
    16141 gattgcaaga caggcaaaag tacgtggaac tgattctaag ttcgccgttg tatttgctgc
    16201 agttggtata acttttgaag atgctgaatt ttttataagc gattttaaag caactggtgc
    16261 aatcgaccgt tctgtagtgt ttgtaaacct tgcaaatgac ccagctgtag agcgtgtatc
    16321 tacacctaga atggcactta cagcagcaga ataccttgct ttcgagcaag atatgcatgt
    16381 acttgttata ataacggata ttacaaacta tgcagaggca ttgcgtgaag tttcagcagc
    16441 taaaaaagaa gttccaggac gtcgtggata tccaggatat ctttatactg accttgctac
    16501 tatgtatgaa agagcaggaa aaatgaaagg gcatgaaggg tctataacta tgattccaat
    16561 acttacaatg cctgaggatg ataagacaca tccaattcct gaccttacag gatacattac
    16621 agaagggcaa attatactta gccgtgaact ttataaaaaa gatatacagc ctcctataga
    16681 tgttttacca tcactttctc gtctaaaaga taaaggtatt ggtaaaggta agactcgtga
    16741 agaccatgca gatacaatga accagctttt tgcagcttat tcaagaggta aggatgcaaa
    16801 agaacttatg gctatacttg gtgaatctgc actttctgag attgatttaa tgtatgctaa
    16861 gtttgcagat gaatttgaga aagaatatgt ttcacaagga tttagaactg atagaactat
    16921 tgagcagaca ttagaaatcg gatggaagct tcttagtatg ttaccaaaaa gtgaacttaa
    16981 acgtatccgt gatgaatatt ttgaaaaata tatgcctaag gagtgatatc tgtggctaga
    17041 ttaaatataa atccaacacg tatggaaatg actagactta agaaactcct taaaactgct
    17101 acaagaggtc ataagcttct taaagataaa cttgatgaac ttatgaaaca atttcttgag
    17161 attgtaagag aaaataagcg attgcgtgaa gaagcagaaa atgctcttga tactgcttat
    17221 aaaaacttta taatcgcaag agcagttatg agtcaggagt atctgggttc agcacttatg
    17281 atgccaaagc aatcagtttc agtagatgtt tctacgagaa atataatgag tgttgatgtt
    17341 cctgtgtttg actttaaaac tgaaaacaat caaagtgata tttatcctta tggtcttgct
    17401 tttacatcag gtgaattaga ttctgctatg gaagctttct cagatgctat gcaaccactt
    17461 ttaagacttg cagaaagtga aaaaagtgca cagcttcttg cacaagagat agaaaagaca
    17521 cgtagacgtg ttaatgctct tgaaaatgta atgataccaa attacattga gactattaag
    17581 tatatagcta tgaagcttga agaaaatgag agagcaagta ctactagact tatgaaggtt
    17641 aaggatatgg tgcttaaaaa agcacttgaa gaaaagaaaa aaaatgattt ggttgtataa
    17701 ttaaatactt ataaaaataa gtctaacatt ctactttata gaggttagac ttatttttta
    17761 tgtttaaatt aaaatgtaga tactataaaa attaatatat tgtttaaaaa cagactgtat
    17821 ttaactaaaa ataatatatt taacaaaaat ttctaaaaat taacgaactg ttaatttaca
    17881 cttaacttta tattaacaaa ttaggtgtat tatataaaca taagcaaaaa caataaaaaa
    17941 caaataaaaa aaggaaaaaa cacaaagggg gaagatatga aagaatttat atttacttgt
    18001 ctgtgcattg tagtgattac atttatgaca agttgcatat caacaacacc acaaactact
    18061 caaggaaaag gaaataataa acttacaata tatgcagcac tagaggaaga gcagatagct
    18121 tattatatgg aaggttttag agaagagtat cccaatatag atgtagagat agttatggat
    18181 tctcatggtg taatagcttc aaaactatta gcagaaaaag ataatccaca agcagatatt
    18241 atatggggat tatcagcaat gaacatgata gagctaaaaa aagatggtgc acttgaagca
    18301 tataagccta aaaattatga taaagttgat aaaaaattta aagatactga agatgatgtg
    18361 tcttgggtag gaatgagtgt cccagagaca gcaatagtag ttaattataa ggaacttaag
    18421 aaactaggta tagatattcc aaaaagttat gaagatttaa taaaaccaga atataaagga
    18481 cttataacaa tgccaaatcc agcatcatct ggaacggggt atcttacagt atcagggctt
    18541 attcaaatga tgggtgaaaa agatgcttac aattacatgg ataaattaca taaaaatata
    18601 gccacatata cacactcagg ttcaaaacct gcgaagttag ctggctctgg agagtatcca
    18661 ataggtatta cacttggata tagagctaca caacaattat ctagtggaga acctatagag
    18721 gttgtatttc caaaggaagg ttcaggttgg gacttagaag caaatgcctt agttaaaaaa
    18781 gataatataa aaaaagaagc aaagctattt ttagattggg caataagtga ttcagctatg
    18841 gatagatatg cacatgaagt agcagttact tccataaaga cagataatcc agttccaaaa
    18901 ggttattcta aacaaccatt tgaacagctt ataaaagaag ttgatttaaa ctctgctgcc
    18961 aaaaacagaa gtacagtact taaaacttgg gaatcaaaat acggttcaaa atctgaaagt
    19021 aagtaaagtt taaattaata atttagatga aagaatttta gaagaaaaag taggatataa
    19081 aatttaaaat aaaaaaataa ctatataagg agagataaga tatgagttac ttaaaaataa
    19141 ataatgtgtt taaaagttat gaccaaaaaa aggttttaaa taatattagt ttggatattg
    19201 aagaagggga atttctatgt ttactcggac ctagtggatg tggtaaaact acattactta
    19261 gaataatagc aggtcttgaa gatgtaaata gtggaactat aattctccag gataaagata
    19321 ttacaaattt agagccatca aagagaggtt ttggtatagt atttcaatca tatgcattat
    19381 ttccgaatat gactgcttat aacaatatag cttttccact aaaagagaga aaagtttcaa
    19441 aagaaaaaat agataataaa gttaaggaag tacttgaaac agttggattg actaatgaag
    19501 ctcataaata ccctaaagca ttatcaggtg gacaacaaca gaggattgca atagcaagag
    19561 cattagctct tgaaccaaag tttttacttt tagatgaacc aatgtctgca ttagatgcaa
    19621 aggttagaca caagcttaga atggacatta aaagattaca aaaagaactt aatataacga
    19681 caataatggt aacacatgac caagaagaag ctataactat ggcagataaa atagctattc
    19741 taaatggagg agatataatg caaataggga ctccagaaga aatataccaa aatcctcaaa
    19801 acctatttac agctcaattt ataggagata caaactgttt tgataatgga gattctatat
    19861 taactgtaag accagaatat gttcaaatag agaaatcgac aaaagaaaac taccaaggga
    19921 taatatcaaa tatagagttt agagggaatt tattgagagt tgaaataaaa gataaattaa
    19981 atgaaaattt cataataagt gatgtttcta taaaagagtg ggttaattta aatttagtag
    20041 aaggtgacct tgtaaaaata agtatagacg aaaaatacta tttaaagtat ccaaaagtta
    20101 aaggagcata agtgtatgaa taataatgct ataagttcta aaagtataag tcttaaatca
    20161 aaaatgaatt tagatataaa aaaatgtatg cttacagtat tagttatgtc tttagtaata
    20221 tttttattag cacctataat atatctattt gtacaggctt ttttagataa agatggagtc
    20281 tttgtaggat tacaaaactt tcaagaatac ttggcttctg aatctctatt aaattctcta
    20341 aaaaatacag tatttgtatc agttatatca actgtaatat cactaacact tgcattagta
    20401 tatgcatatg cattaactag aacaaagatt aaatttaaag gtttttttaa atcattagct
    20461 atgtttccta tgtttgctcc aacaatgatg catgcaatag gtctagtata tttatttgga
    20521 aatcaaggtt tggtaactaa tttacttgga gtgcatgttc caatatatgg agcagtggga
    20581 ataatattgg cacaaattat atatgtattt cctcaatcct ttcaaatact ttatatatct
    20641 ctaagttcaa ccgattatag actatatgaa gctagtaata ctatggggat aagcaagata
    20701 agagaattta taagcataac aatcccaagt ataaaatact ctttaataag ttctgcattc
    20761 gtatcgttta cattatgttt tacagatttt ggagctccaa aggtgatagg aggagagttt
    20821 aatgtattat caatagatgt atataagcaa attatagggc aacagaatat gccaatggga
    20881 gcaactgtat caatattact tttaatacct gcaataatat cgtttatagt aactaaaaaa
    20941 attgaaaaaa atcaaaattc atatataact tcaaagtcaa ttccatataa ggttaaaact
    21001 aataagttaa gagatagtat tttaggaggg gttgtaggaa ttattgcatt tggtataata
    21061 gctgtaatgt taactgtaat cttatcttca ttaatatcag tttggccata tgatttaaga
    21121 ctgacactgg aacatttttc tatgaaaaac agtattgatg ggattaaacc atttataaat
    21181 tcaataaaaa tgtcactatt tacagctatt ctagggacga gctttgtttt cttatttgca
    21241 tatttgaatg aaaaaacaga aaaagctcca tatttaaaat catttgggta ttttttaagt
    21301 acattgccta tggcattgcc aggattagtt ttaggtatag cttatgtatt attttttaat
    21361 aaattagagt ttaattttat ggatacaata tacattaaga atttgtttaa tggattatat
    21421 ggaacattac ttataatggt tatatgtaat atagttcatt tcttttcagt agcatttata
    21481 acagctacta ctgctattaa gaaagtagat aaagaattag atatggtagc taaatcaatg
    21541 ggaataaaca gcgcatcaat tcttaagaac gtaactatac cactttgttt gccagcagtt
    21601 ttagagaact ttatgtactt tttcctaaac tccatggtga caatatcagc attagttttt
    21661 atatatactg caagttcaaa agtagctgca atatcaattg tacaactaga tgataagggg
    21721 agtactgcac aggcagcagc actagctgtg ttaatattag tcacaaatat attagtgaaa
    21781 gtaatatatg aatttataaa gaatcgttta gaaaaaagaa caaactttaa ttaaataatt
    21841 tatcttataa aaacacaaat ttaaaaaagt ctattcttgt gatttattat ttaaagaata
    21901 gactttttaa atttattatt gatattgttt attaattttc cttttgttat catacatttg
    21961 agaatctgca cgacgatatg tatcaaataa agaaacatct actttttcat caaaaatagc
    22021 atatccaata gacattgata attttaattc attagttgag ttttcttcaa ctatttttaa
    22081 attaatatta tttataatat tatttatttc tttgtgagat aaatttttta gaataattat
    22141 gtattcatca cctccaatac gataaactat atatttttta tttattacat attgtataat
    22201 tttacttgct tgcttaatat ataagtctcc tgtctgatgg ccaaatttat cattaatctt
    22261 ttttaaaccg tctaaatcta ttgatatgat agatattaga ttctttagat ttgaattgtt
    22321 taagttattc atatctattt caaaagcatt tctatttttt aggcctgtta aataatctgt
    22381 attagcaaaa tcagtatatg taggattaga tattctttta aatagaatca ctgcaatcaa
    22441 tgctgatatt agacaagtta ataatgctat tattggtgta actatactta taaatttaaa
    22501 tgtattgtat tgatgttttg cttcaaattc aattcctatt actccaacaa ccttaccaac
    22561 atcattgtga ataggaaaat acgatataaa tatgtatccc caagatgttg atttaatctt
    22621 tttaggtaac aatatatgat tatctaatgc tttgttaagg tctccccaaa tctctttttc
    22681 tatcaaatca ccagcatttc taaaatcact cctagatgaa tttaaaccat caacaacata
    22741 tactagtgat ccatcttttg tttttttagc agtatataga tacatgactc cagtagtatt
    22801 ttttacagat tctaaaagga ttttagaact tttataagac ttttttgatt ggtcttcttt
    22861 agaattaatt tcagtaaagg tatttttatc aatatttctt tctacatatt catagatatg
    22921 ttttgacctc tcacttaaag agtatatcat gctcttataa gttagtgtat aattaaaaaa
    22981 atatacacat gaggaagata ttattacaat aattgcagta agtattgaaa cctgcatatc
    23041 aactctattg aattttttat ttattttcat agcttaaatg tcttgtgaaa agaacctccc
    23101 acaatctccc cataattaat atatatctat aaatctcacc ataatatatt catatattat
    23161 caaatttgtg tggaaattac aattagtaaa catgcttaaa gcattcaaat atagtttttt
    23221 tattattata gtatactatt ttatgtataa ataaaattat atataaatca ttgatattgg
    23281 ttgtttatta atggaagata ccgtataaaa tattctaatt ggttacgata tgtatactta
    23341 attgaagtta agttaagggt tagaatatgt attgatgaaa tggctagatt tatattcata
    23401 agtattaatt ttatcataga taggtaaaat actgtatctt aaacataagt atgattgaga
    23461 tgcaatcctg agatatgata atataaattg aaggatagtg aactcaatca aataaaatga
    23521 ttaatctagc tatataagca aataaattta atataaaaga ggtggaaaat gaaagacaga
    23581 cttaatttaa cagaaggaag aattacagaa aaattactta agctatcact tccaataatg
    23641 gggacttcat ttatacagat ggggtataac atgatagata tgatatgggt tggtaaagcc
    23701 ggaagtaaag cagtagctgc agttggaaca gctggttttt ttccatggct tgcaatggca
    23761 tttattatga tttcaaaagt aggtggagag ataaaagtag cacaaagtat tggtgcaaat
    23821 aatataagca ctactaaatc atatatgaag tcagcaatag aaataaatat tatactagca
    23881 ataatatata caatttcttt aatagtactt aataaacaat tgataggttt ttttagatta
    23941 ggagacttag aagttataac catgtctaga cagtatttga taatagtagc tctaggtatg
    24001 gtattttatt ttattaatcc agtatttact gcaattttca atggtcttgg aaatagtaaa
    24061 actccttttc gtattaatac agtaggatta ataactaata ttatacttga ccctatatta
    24121 atttttggat ggggatttgc tccaaaactt ggtgttgcag gagctgctat tgcaactgta
    24181 tttgctcaga tagtagttac tacatgtttt atatatataa tagttaaaag taaagaagaa
    24241 tattttaaat taagactatt taaagaaata gagactaaat attataaagt tctgtataaa
    24301 ttgggattac ctatagcaat acaaagtggt atgtttacag tattctcaat gctattagga
    24361 gtaatagtag catcatgggg gcctgtggct gttgcagtac aaaaagtagg ctcacaaata
    24421 gaagcaattt cctggatgac ggctgaaggg ctatcagttg cattaggcag ttttgttgga
    24481 caaaattatg gtgccaagaa gtattctaga ataaataaag gttgcaaaat agctataact
    24541 gtatcttctg tacttggtat aataactact ttagtattag tgtttgcagg agagagtata
    24601 ttttctattt ttatagatga aagtgaggca atagaaaaag gagcagttta tcttaaaata
    24661 ttaggctatt ctcaattttt tatgtgttta gaaataataa caacaggagc tttcaaagga
    24721 ttagggagaa cctatatacc ttctattata attactatac tgactggtgc aagagtacca
    24781 ttggcttact ttatatctag accagaaatg ttgggtctaa atggtgtatg gtggagtata
    24841 accttatcaa gtatattaaa aggtatatta atgataagtc tatttatatc tttattaaaa
    24901 ctcggaaagt tgtacaagat ttctgaataa aatttaaatt atcttaaatg tatagacatt
    24961 ttctttgttt gtatataaaa ttatcttatt atataaaaga tttaataagg agtgaattaa
    25021 atgaaagagc caatttataa agttatagaa aatcatgtta gagagttaat aaattcagac
    25081 agtttgaaag aaggggattt aatcccttct gaaaaacagc tgagtgaaga atttaatgta
    25141 actagaatga ctgtaaggtc tgcacttaat aatctagtta aagaaggcta tataactaga
    25201 caaagaggtg taggtagtat agttattgca aataatatat atgataatat atcgtctgta
    25261 agtggattta ctaaagagat ggaaagtaaa ggctataaag tatctaatat attggtatct
    25321 cttgaaatag ttcaggcaga tgaaaattta tcaagtaagt tgaatataag tttagaagaa
    25381 aatgtttggg aaataaaaag agtaagatta gccaatgatg caagagtttc atatatgatt
    25441 acttatatgc cagttaagtt atttccaaat ttaaataaga ctcattgtga agattctctt
    25501 tataattttg ttgaagaagt gtgtggatac aagatagcca tgtcagagag agaagtacaa
    25561 gctgtaatat cgaatgaaga gtgtatggat aatctaaaat tagaagaacc agagccactt
    25621 ttatatataa gccaaatttg taagttacaa aatagtgaga tttttgagta ctcacacaca
    25681 tatcactatg gatatacatt aactttgaat gctgttgtcg aataaaattt aaataaaatg
    25741 aaaaagtttt cttgaaatgt atatacattt ggtatataat aatatcaaga attaaatgta
    25801 tatacattta aaaataagat atatacatta agaaaaaatt aatagaaaag catattttaa
    25861 atgtatagtt taaaaaactt atgacttaaa aaatatttaa tgaatctaat ttggagggga
    25921 aaaaatgata aaaataatgt tagcttgttc agcaggaatg tcaactagtt tattagttac
    25981 aaaaatggag gatgcagcaa aggaaaacgg tatagaagca aaaatatggg ctatatcaga
    26041 agtgaactta aaaaatgaaa tagaaaattg tgatgtctta cttttagggc ctcaagttag
    26101 atatgtatta ggaaaagcaa ctgaaatggc aaaaccatat aatattccag tagaagttat
    26161 aaatatgatg gattatggaa gatgtaatgg aaaagctgtg ttagatagag ctgtagagtt
    26221 aaatagttca aaataaagtt gtactggagg atgtaaaatg gaaaaattca tgtcatttat
    26281 ggataaatat atagtgcctg tagctgctaa aataggagct caaaggcact tagtagcagt
    26341 aagagatgca tttatagtaa tgatacctat aactatggta ggtgcattgg gaacattgat
    26401 aaataactta ccattggaag catacaaaaa tttgatggca agtatatttg gagaaaactg
    26461 gaccacattt ggaggcgacc tttggtgggg agcaataggt acaatggcag tattcttagt
    26521 aataggtgtt gcttattttc tagcaaaatc ttatgagagt gatgggttac aatctgggct
    26581 tatagcttta tctatctttt ttataatggc tccacaaatt ggtaaaatag ttcctgaggg
    26641 aggaactaca gtagttgaag gatggggaat gatacaacaa acctacttag gtacagcagc
    26701 tttattctct tctatattaa taggattatt atcaactgag atatttgtaa gattatctaa
    26761 ggtaaagaaa ttaactataa aaatgccaga tggagttcca ccagcagttt caagatcatt
    26821 tgcaaagtta ataccaggaa tgttaactat aatgatattt actgtaatag gaatatttat
    26881 aaaaatgctt tctaatggaa gtttcttaac agatatttta aatacttatt taggagcacc
    26941 actatcaaat gtagctgata gtctaggttc tacaatgctt attgcattta taattcatat
    27001 actttggact gttggacttc atggtgcaaa tatagcactt ccttttacag aaactatact
    27061 tatgaaatta ggtggagaaa atgctgcctt ggctcaagca ggagcaacgg aaggatacca
    27121 tgtacttgca ggtgcattct ttgatgcatt tgtgtattta ggtggttctg gaatggtatt
    27181 gggattaata gtagctttat taatagctgg aagaagacgt aaagagatga tagtattagg
    27241 tggtccacct gcaatattta acataggaga accattgata tttggacttc caatagtttt
    27301 aaatcctata tttatgattc catttgtact tgcaccagta atatgtagtg ctgtatcata
    27361 cttagcaata gattttggat tagtagcacc agtaatttta cctaaaatac cttgggtaac
    27421 acctcctata ttaggtggag caatggctac aggtgactgg actggtggag ctttagcact
    27481 atttaattta atattatcaa tattaatata tattccattt gtcatagcgt ctgaaaaaat
    27541 ggaagctaat aaattgaaaa ttaacaacta ggtagtttta tttcggtaaa taaatgtata
    27601 gggttttgta gagtatatta aattataggt aaggatggta taatgagatg aaaaagggac
    27661 taaaaatagt tacaattgga ggaggttcaa gttatactcc tgagcttgta gagggtttta
    27721 taaatagata tgaagagtta cctgtaaagg aattatggct tgtagatata gaagctggaa
    27781 aagaaaaatt agagatagtt ggaaatctag ctaagaggat ggtaaaaaaa gctggagtag
    27841 atatgaaaat aaatcttact ttagatagaa gagaagctct aagagatgca gactttgtga
    27901 caacacaact tagagtaggt cttttagatg cgagaataaa agatgaaact attcctttat
    27961 ctcatggagt tatggggcag gaaactaatg gtgctggagg tttatttaaa gcccttcgca
    28021 caataccagt tatatttgat ataataaaag atgtggaaga attatgtcca aatgcatgga
    28081 tggtgaattt tacaaatcca acaggaataa taacagaggc tgtattcaaa tatactaatt
    28141 ttagaagata tataggtcta tgcaacgtgc caattcattt aaaaaatgat gttgccaaac
    28201 tatttaatgt agaaagtgac agaataagta tggattttgc aggtcttaat catatggttt
    28261 atggtctaaa tgtatcttta gatggagaag atgttacaaa agaagcaatt gataaatttg
    28321 tcaaagcaga tataagtatg caaaatataa aggcaattga ttttaatgct gaatttgtaa
    28381 aatctttggg tgcaatacct tgtccatatc atagatacta ctataaaact aaagaaatgc
    28441 ttgaggatga gttgagagag tttaaagagg gaaaagctag aggtcaagta gttaaagaat
    28501 tggaagaaca attatttgaa ttatataagg atgaaaaatt agatgtaaaa ccacctcaac
    28561 ttgaaaaaag aggaggggct tactatagtg atgctgcttg taatttaata agttctatat
    28621 acaatgacaa aaaagatatc caagtagtta atacattaaa caagggttct ataagagatt
    28681 ttaaagatga acaagcagta gaagtaagta gtgtaataac aaaaaatggt ccaaaaccaa
    28741 taagtatagg atatttacca gattctgtgc atggattagt aagtcaaatc aaatcatttg
    28801 aagtattggc agctaaagca gctgtatatg gcgattatga atctgctctt ttggcacttt
    28861 gtacaaaccc attgattcca tctgatgact tagcaaaaac tatattagac gaaatgttgg
    28921 aagctcataa agattatctt cctagattta atagatagtt gtctatagaa agtaggttat
    28981 ggtatgacta aaattataat aaatgcagat gattttggat attgtgaagc tgtgaactat
    29041 ggaataattt cagctcataa taatggtata gttaggtcta cttctatgat ggcaaatatg
    29101 cctggggtag aacatggagt aggcttactt aaagaaaata aaactttaaa ttgtggagtt
    29161 catatgactt taagttgtgg tagaccatta ttatctaact taaaaactat tgttgataaa
    29221 gacggttttt ttattaggag gattacagac gaaattattg aaaaaatgga ttgtgatgag
    29281 atttatagag aactttgtgc tcaaatagat agggtaaaag ggcttggaat agatatatct
    29341 catttagata gtcaccatca tatccatact ttagtaagtt taaagccagt aatagagaag
    29401 attgtaacca agtataatct tccgataaga ggtggatttg aatataattt agagtattct
    29461 aaagtagttc ctttaataga tagtttttat aaggaaaatg taagtgaaga atattttata
    29521 aaaaatatag acgaaataat gaagtatgat gtagtggata ttatgtctca cccagctttt
    29581 ttagatgatt atattttaaa ttctacatct tatgctattg atagaacgaa agagcacaag
    29641 atacttacat ctaaaaaagt caaagaattt ttagaaaaga atggattagt catatcaagc
    29701 tatagagata tttaggaggt cgaataaatg gatgagaaga tgatagagat atcttttgga
    29761 ataattggat ttgcaggtga tgcgaaaggg ctagcatttg aagcaataaa agaagcaaag
    29821 agcgggaata tagataaagc tagagaatgt attgaaaagt cgaaagaatc aattcataaa
    29881 gctcataaat tccaaacaga attgatacaa aatgaagcta atggtaataa aactgaaata
    29941 agtgttatac ttattcatgc acaagaccat ttaatgacag ctatgaattt tcaacaatta
    30001 gcagaagaat ttatagatgt atatgaaaga ttagaaagta agtaatttaa atttattatt
    30061 aaaaaagagt gtataaaaat aatttttata attattaaat gcactctttt tttatttaag
    30121 tagagtttag caatatagta ttatgttatt gatactttag aatttagact tctcataatt
    30181 gtaaggtata ctagtaccaa caactacatc ttcaattttt tcaacaataa gccaatcatc
    30241 catatttcct tgatggtcaa aatcaagagg tgttatttct tcaacatttt caaattcaac
    30301 taagcataaa cattttttat gccaacgaac tttttgcttt tcagataaat ttaattttgg
    30361 ttgattttca tttaaaattt tagaaatttc atcttctgtt aatttaacat agttttctac
    30421 ctttttaaca gtggcttttg cagatatttt tgcagttcct ttttccataa aataaagtaa
    30481 ctcatcttca aatactctac tatgtggtat ttttctacca gcagcacctc taataaccat
    30541 tgtttttgtt ccagccaaga ttttatctaa gaccttttct cctttttttc ctgcattatc
    30601 acaatatact aaatgtacca tgttttgaat cctccttact aaattcatta tctataaatt
    30661 gcattttatc attgtttaac tgaaaagtca ttgtatttgt gtccaattct ttaaaaaaat
    30721 actgtttaat ataagaaaac cttatctaag ctatatataa ttaagattaa ttaggaattt
    30781 ttatcctttt acaaaataat attgactaaa aatagaaaaa tgctataata aatatgtgct
    30841 tatgataatc aatatcatgt aagtataata aacaagtagg agaagtaatc atgaaaaaaa
    30901 taaaatcact tgcaatattt atatctatta taactacatt agtacttgtt acagcatgtt
    30961 cagataagaa tacagaggat aaagataaat cagagacaag agttgtacaa tctgttaaag
    31021 gagaggttaa gataccatca aatcctaaaa aaatagttga tatatcagga agtagtgaag
    31081 aactattatt agcaggttat aagcctgttg caacagcaaa tgtagactca tatgaaactg
    31141 ataaattacc aagttacata agagaagagc ttaaaggtgt aaagatagtt gggcactcaa
    31201 tgatggatac tatggatatg gaagctatat tagaagtaaa tcctgattta ataataatga
    31261 gtcaaagaca agaaaaaata tatgaccaat taaaagaaat agctcctgta gttatgatga
    31321 aagattatgc aaatgactgg agaagcaagt taactgatgt ttcaaagtta tttgacaaag
    31381 aagaagaagc taaaagttgg ctacagaagt atgatgaaaa agctacaaag ttaggtaagg
    31441 aagttataga aaagaatgga gaaaaaactt atttaccagt gttggcaagt tcaggtcaat
    31501 ttatggtatt tagtgatggt ggaataggta ctctaatcaa tgatgatatg aaattagcta
    31561 gacctaagaa tatgccaaaa caggatggaa taacactacc aatggtaagt atggaaggtt
    31621 taacagatat agatgcagac catatagttg taattgctac agaagcagat aaaaaagatt
    31681 tagaaaatag tgctatctgg gctcaaataa gagcagtaaa agatggtaat gtaacaatac
    31741 ttgatgctgt tccatttttc agtcaatcat acaatccaat tggaaaagag ttattattag
    31801 aatcagttaa aaatgaatta acaaagtaat tcttaactta gtaggtgtga gataatgata
    31861 ttcatttttc acacctattt ttaataaatc ttaaaattaa aatacttaat agatgatatt
    31921 atactgacga ttaaaaggga aaaggaggta ggataattga ctaagctgag taaaaaaaat
    31981 ataacttatt tgttgatatt agtaagtata gttgtacttg tatttggaat tgtattatcc
    32041 ataactattg gggcaaaaga tatgaatcta tcaactgtta tagatagttt gataaaaatg
    32101 gaagatggaa taaatatgag aatagtaaag gatgttagac ttccaagggc aatagcagct
    32161 gcacttgttg gagggttttt agcagtttct ggggcaataa tgcaaggaat aacgagaaat
    32221 cctatagctg aaccatctgt tataggaatt acacaaggag ctacattcgc aatttcgata
    32281 tcactggtac ttcaaaaaaa acttcctcaa cttatacatg gaagttttag tgtaatgatg
    32341 tttgcattta ttggagcaag tataagtgga ttatttatat attttataag ttctaaatca
    32401 agaggaagag ttaataatgt aaaattagct cttgcaggag tcgctcttgg tacattgcta
    32461 atttctttgg catcagcaat atctatgtat tttaacctat ctcaacaatt aagtttctgg
    32521 atatcaggag ggcttgtagg agtgaagtgg gaaggtataa aattgctatt tgtagctggt
    32581 ggtattggat ttattttagc tattattatg gctccaagaa taactatatt aagtcttgga
    32641 gaagaagtgg caataggatt aggacaaaaa actaactttg ttagatttat atgtatagta
    32701 cttgtaatat taatgactgg agcatctgtg tcagtgtctg gtaatattat ttttataggt
    32761 cttatagttc ctcaaatagc taaaggaata gtaggttcag attataagta tataataccg
    32821 agctctttag tattaggagc tgtattgctt gtatatacag atatattaag taggatgata
    32881 aatcctccat atgagacacc agtaggttct ataacagcac ttataggagt gccaatattt
    32941 atataccttg ttagaaaggg ggagaaatag gtactatgaa aaatattata aaaataaatt
    33001 ctaaaacatt acttgttata tcaattttaa tggtgcttat ttttatcact tttttattga
    33061 gtttaaatat gggctcattt tctatagaac caatggatgt tataaagact tttttaggga
    33121 agggtcagcg taatcatgaa attgcaatat ttaaattaag attaccaaga atagtaatag
    33181 cacttttggt tggttctgca ttatcaacag caggtgtaat acttcaagga gttacaaaga
    33241 atgatttagc tgattctgga attttgggaa taaattcagg tgctgcattg tttgtagtag
    33301 tttatatata tcttatgaat ggtaatgtat atgaaggtat gagtaacttg actgtattta
    33361 caatgcctat tgttgcactt ataggagctt tatttggagc atttcttata tattctcttg
    33421 catggaaagg tggtataaat tcgtcaagat tactacttat tggtataggt gtaaacatag
    33481 cttttacttc aattttgacg atattccaat tgaaatttac aacacaagaa tttaataggg
    33541 ttatggcatg gacatcagga agcatttggg gaaccagttg gaaatatgta atagctgtgc
    33601 ttccatttat agtgattttt atgggtataa ctatttataa atctaaatat atagatgttt
    33661 taaatttggg tgatgaagta tctataagtc ttggtgtaga tgtagaaaaa caaagaagaa
    33721 gacttataat atatgcagta attttatctg gtgtatcgac agcagtagca ggtagtattt
    33781 catttttagg tttaatagct ccacatatag gtagaaaaat aataggacca aagcataaaa
    33841 gattaatacc agtatcagca ttgataggaa cattattact tttaatagca gatactatat
    33901 caagaaatct tctagcacct atagaaatac cagtaggtat agtagtttct ataataggag
    33961 tgccgtactt tatttattta atgttggtaa atgattagga aagggtgttg ttatgaactg
    34021 tataaatact aagaatctaa atgtatcata tggaaacaca gatattataa aaaatttaaa
    34081 tttaaatata ccaaaaggaa aaataactac catcataggg gctaatggtt gtggaaaatc
    34141 gacaatactt aaaactatag gtagaattat tagccctaat agtgggaaaa tatatataaa
    34201 tggagaggac atctacaaaa agaagtctaa agaaatagca aaggatatgg ctgtacttcc
    34261 acaaagccct caagctccta gtggtcttac cgtttcagaa ttaatttctt atggaagatt
    34321 tcctcataaa agtggatttg gtaattctag taaagaagac agagagattg taaattggag
    34381 tttagaagtt actggaattg cagaatttaa ggatagaaat atggaagatt tatcaggagg
    34441 acaaagacaa agggcatgga tagctatggc tttggcacaa gaaactgata tattattact
    34501 ggatgagcct acaacatatt tagatttggc acatcaattg gagatactaa aattattaga
    34561 tgaactaaat aaaaaacaag gaagaactat tgtcatggta atacatgaac ttaataatgc
    34621 agcaagattt gctgaccaca tgataggtat taagaaaggt aaaatagttt gtgaaggtga
    34681 tgcatatgat gttatgacga aggataatct aaaagaatta tttaatattg atgcagaaat
    34741 agcaacagac ccaagaacaa ataaaccaat ttgtataact tatgacatgg tgtaaatggt
    34801 gacaacatgg agaatcaaga agcattaaga catgaaaaaa tatggatttt attatttagg
    34861 tattcgatac ctgcaataat agcaatgatg gtaacttcac tttataatgt agtagataga
    34921 gcttttattg gttctatgga aggtattggc tctatagcta ttgcaggtct tggtgtaact
    34981 atgccagtat ttactctaat aatagctttt ggaatgttgg tatcagtagg tgctagcaca
    35041 agattgtcta taaagttagg tgaaagaaat agagaagaag cagagaagat attaggtaat
    35101 gctttgacat tatctataat tatctcttta attataacta tattaggatt agttttctta
    35161 gaagatatac tttttatttt gggtgcaagt aaagattcaa tattttatgc aaaagactat
    35221 atgagtgtca tattggttgg aagtatattt aatttagttg cattttatct taataatgca
    35281 attagggcag aaggtaatcc aaaattagca gcaaggacaa tgattgtagg atgtgtatta
    35341 aacctgatat tggaccctat atttatattt gtatttaatt taggtataaa aggagcagct
    35401 atagcaacag tactctgtca aatagtagta ttcttttggg taatacatta ttttataaga
    35461 gggaagtcca atttaaaact aaaaaaatgt aacttaaaat tgaataaaga tatagtaaag
    35521 aaggtatttg caataggaat gacacctttt gctatggaag tagctataag tataactcac
    35581 atgtttacaa ataattctct aaaggtttat ggtggagatt tagctattgg agctatgaca
    35641 gcacttacat ctattttatt gatgtttatg atgcctgtgt ttggattgaa tcaaggtatg
    35701 caaactataa tatcatacaa ttatggtgca aaacaatatg agcgtgcaaa gaaaacttta
    35761 atattatcta tcatagtgtc agttgtcata ttgtcatttg gatttttagt agtacaagtt
    35821 ttcccagaag tatttgtagg tatatttaat aaagattcag atttgatgga tatagcagta
    35881 agaggtataa gcctaaatct aattacattg cctataatgg ggatttctat tgtaggacct
    35941 gtgtattttc agtgtataag taaagttaaa cattcaatgt ttttaactct tttaagacaa
    36001 tttattttat ttataccatt aatcattgta cttccaattc aatttaattt agatggtgtt
    36061 tggttggcac agccagttgc agattttatt gctatgataa tcgtattatt attcttaaaa
    36121 agggaattta aaacaagccg agtgtaagaa atttagaaaa taaaattaaa ttggaaaata
    36181 aaaagacttg tctttataaa atgattaaaa ttattttata gagacaagtt ttttatttta
    36241 tttaaacgga actatccata ctggtttctt ctagtttttt tccaaaagtc attttctcaa
    36301 atatttcttg aggtagaggt tttgaaaaaa catatccttg tatcatatca caattaattt
    36361 ttttaagata atccatttgc aagattgttt caacaccttc tgatatacta ttcatattta
    36421 atttttttgc caaattaact atagattcta ttacatgatt ttcagcaata ttatctgcat
    36481 taggtgagct aaaaaaagca cggtcaagtt ttaatgtgtc aacttttatt tcttttaaca
    36541 tattgagtga agagtatcca cttccaaagt catctagtga acattgaaaa ccttcttcat
    36601 ggatttggtc tattatatta attaattttt ggagattttc aaatacaagt gtttcagtta
    36661 attcaatttc taagagcttt gcaggaatgt tgtatttatt acgaagcatt ctgtattttt
    36721 ctaaaaaatc tatattattt aaattagcac gtgaaaaatt aactgaaaca ggtattggag
    36781 tttctccatt atctatccat tttcttatca tactacatac tttttcaaaa acatagtggt
    36841 cgagttttgt aataaaacca tttttttcaa agaaaggaat aaactcgtct ggtggtataa
    36901 ggcctttatt tgggtcttgc catcttacta atgcttctgc acctacaata gtattatctt
    36961 ttaggctgat tttaggctga agatatacta taaattcgtt attatttaat gcttcctcca
    37021 ttctattttc catttctttt tctttaatca tttttaaacg ctctaaatca ctataaaaaa
    37081 cacatgtata aagtggatga tttccaatgt ttcctttatt attttttcgt gcaacatttg
    37141 cacggtcttg aattgaaact aaaggtagat ttgggtcatc aattttatat acacctatag
    37201 atagagctat aaaatattta cattcttcat ttttattgaa actattaata tcattggtga
    37261 tattttctat gtacttaaga atttcttttt gaggaatagt tttaataagt acattaaact
    37321 ggtcattaga aactcgacaa agcaattctc ctggttctag ataattacta atgacatcat
    37381 gtatgtactt taatgtttta tctcctgctt cactaccaaa agaatcatta ataagtttga
    37441 atttctgaat atttatagat accaatgaat agctttctga tgaagatgac tgtataattt
    37501 ttttagcttc aatatcaaaa cgtgctttac tgtaaccttt agttacagag tctacatagg
    37561 cgatttttat aagttgtgcc ctgttctttt gatttataaa cataatcaat ataataagca
    37621 ataaaaatag tataacaatt aaaatattga tgaagattgc tttttttaga agtaaatcaa
    37681 actgtgcact tgctgttttt gttggaacaa ttgaaaggag gtataagttt tcttcttgta
    37741 atggaagata gtgcattgcc ttagaaatac catcatttaa tgtataatac atagaaccag
    37801 ttttgttctt ttttaagttt attttcattt cttcaagttt atttttatca acctgttttc
    37861 cttggtgttt aatcatgtca aaaaaattta ccacattttt tggagcattt ttgtttgctg
    37921 aacttacaat aaaatttcca tcttggtcga taatttggga aaatccttca ccatgaaagc
    37981 tttctacact taataaattt ctcatagtat caatagtatt ccaagcagca acagctccaa
    38041 caattttatc gccattgtat agtggtacag aatataaaat tccatatgta ccagattgtg
    38101 atttaacagg agtaattgtt tctttgcctt gaagggcttt tctataaaag tcttgtcctt
    38161 taacattacc tgtatcttta agggcactta caaaatttcc attagaatct ataataccta
    38221 accaatcaaa ttcaaataat tttaattttt ttgataagta tctattgact tctttttcac
    38281 tatcattaat ctcaaaataa gtatctccca tagaatatag tgtcctaaat atacttttac
    38341 atttcacatt aattgtagtg gaaatacctt gtgaaacttc tacaagatat cgttctgttt
    38401 cattatgtgt tactttattt agattcataa taaaagtgac acatgttaat gacacgatta
    38461 aaaggagtgt caatagtaaa gtagctatta tttttttatt ttttgtgttt tcaaagttca
    38521 ttcttttgtt tcatcctcca tcctttattt gtttacaaat aagaattctc tcagacatat
    38581 tataccaaat atcttttcat acaaagatat taaattttat ttatcccact ttacatttag
    38641 ctttatttat gtcttcttag agattaatca agatacgttt attgtttaaa tcttatttta
    38701 taatattttg agtaaaagag gttaaaaaaa ggaactgttt tcaaaataat tttgatacag
    38761 ttccttttca gtatagaaaa tttttatagt attagaaaga acttttagct tatgtatcta
    38821 cataagtatt atatttataa aagatatttt gttacaatct aaaatgtaga tgaaattctg
    38881 taaatgccaa attctctatg accaagactt tcagctttgg tatgtttacc attacagact
    38941 tctattattt cattaaatat ttcttgacct atatctgcta ttttagcacc atctgttata
    39001 attctacctg catttatatc gatattgtct ggcattttgt tgtatgtatc actattccca
    39061 gtgattttaa taactggtga aatagggctt cctgttggag tacctctacc agttgaaaag
    39121 attacaattt gtgcaccacc tgctaccata ccagtgatag aatctatatc ttgacctgga
    39181 gtatccataa aatataatcc ttttttatca ggaggtacaa tatcagcata ttcaagagca
    39241 cctttgaatg gcttattgcc tgccttatac atacacccaa gtgacttttc ttcaattgtt
    39301 gaaagtccac cagttttatt gcctggagta ggttgaccac tacgtaaatc ttctcccata
    39361 gcaattgctc ttttttctac atcacttaca aatttaagaa acttatcttt catttcttca
    39421 tcttcaaaac gggtagccaa caaatgttct gcaccaatta cttctgtagt ttcacttagt
    39481 atgctacttc caccttcatc tacaagaagg tttgatgcaa cgcctattga agggtttgaa
    39541 gctattccac ttgttgggtc agaaccacca cattcaagtg ctaatgtaat ttcactcata
    39601 ccaaattcaa ctcttacttc ttttgacact tcacgagcca ttttacttac tatttcagct
    39661 cccttagaaa ctgtttttaa tgttccgcca cattcctgta taacaacgta atctaccttt
    39721 tttcctgttg tagctatttc agatgctaat tcttttgctt gaataccatc acatccaaga
    39781 ccaactacta aaactgcggc aacattagga ttttttccaa atcctattaa tgtctttgct
    39841 gtaagctcta tatcagaacc aatttgacaa catccatgtt gatgagggat tgctattgct
    39901 ccaggcacaa gtgatgctat tcttgtagct gtctcacttg aacatacaga tgttggaata
    39961 attaaaacat gattacgaat accaaactga ccattttctc ttaaataacc cattaatttc
    40021 attttaactt cctcctattt tttatctcca cgaccacgtg tactttcaat gttatgtaca
    40081 tgaacatagt caccagtttt tatgtcaact gttgcaattc ctatgatttc accgtatttg
    40141 tatacaacat cacctttttt tacatcttct gtagccatct tatgaaagac aggtatatta
    40201 tcatttacta tgtaagactt tccatcaatt gaaacttttt cacctttaac taaaggtctg
    40261 acacatgtaa ctagattatc tttttcattt gcatgaataa ttgcattcat taattttacc
    40321 tccttaagta ttaatttact tcaatatttt tatttgtttt aaaaatagat tttttctttt
    40381 tttctctttt atctagatag gaaactaaca ttggacaaca tattgctgta acaataatag
    40441 cagcagcaac ctgtactgtt gaaacagctg ctattgtagc tagagtaggg tctatagctg
    40501 ctaaagcttc aggagtacca gctgcatttc cggctgttgt acctgtagct gcacctactg
    40561 ctggatgttc tgcacgtata agtttcatta caaagtaccc acccatacct gttattatag
    40621 taactcctaa accaagtaca actccaggta gtccagcagt tataatttga ttaaagttta
    40681 atgctgctcc taaaggaaaa gcgaagaaag gaattaataa tgttgtacca ggtgcaagaa
    40741 attctcgtat atcttcatca aggttaccaa gtataaatcc aagtagtatt ggtataagtg
    40801 ctgcaaatag tgctactata ggtacatttg caagtccagt tactccaaaa gcaagcattg
    40861 taaaaaaagg accatcattt agagataaga tagatattgc tccaacatct gtggagtctc
    40921 catattcacc tgcaagagca gcaaatagac ctccatttga attagtcatg gtagcaacta
    40981 tggcaagagg tgtaatacca attatacctt taggtccaat aaatttacta acaataatac
    41041 ctaatactgc accaattata aattttgttg ctgtaagtac tataccttta gtcaatggtt
    41101 taccagcttg tctgatattg atttgagctc cattgcatag acaaaataga gcaagtatac
    41161 tcattgcacc agttttaaat aaggatgttg tgaatcctcc aatttcaaga gcttgtggac
    41221 atactgtatt aaatagtgct cccaataaca agggacagac cataagtcct cctggtatct
    41281 ttttcactga ttttaagatg tgcatctagt atcactccct ttcattttta tataggtatt
    41341 ataaaagcaa ttaatatgcc aatatataga gtttgtatct ttagttatca tgattatttt
    41401 taataatcga ttgaaatgct gtagattact tataattaaa agtacgattg acgagaattt
    41461 cacttacaaa gattcttttt atcatataat tgtatttttt attgaaaaca aataaacgtc
    41521 ttatgtatta aaattaaaca taaaacgttt tgatatatat agatatgtat tatttttaaa
    41581 catcatcttc tatttctttt aacttacgcc atagagtgga gcgagttatc tttagaattt
    41641 cacaggtttt tgtagtattt ctattatttt cgttataaat tttatagata tatttttttt
    41701 ctaaagtttt taaatctaaa ttactgcatt caaaatcact attatcttta tcaactatat
    41761 tatttgtata ttcattgcta accttttcta ataaaatcga gtcaaatgat tccacaataa
    41821 cagccctttc catcatacct tccaattccc ttatattacc ttcatattct cgttcaagaa
    41881 gtgccttttt aatatttgga gtgataatta agggcgtttt attgtatttg tttgaatatt
    41941 tatgtataaa aaattctgat aattttataa tatcttcttt tctttctttt aatgaaggaa
    42001 gatataatgt tagtatattt attctaaaat aaagatcttg tctaaataaa ccattgcgca
    42061 tcatattttt taagtcttta tttgaagcac agataatttt tacatctata ggaataactt
    42121 tatcaccacc aattctcata acttgttttt cctgcaatac tctcaataat cgaccttgaa
    42181 gttcaagagg gatttcactt atttcatcta ggaagattgt accttcatgt gctagttcga
    42241 atatacctgc tttacctttt tttctagcac ctgtaaatga accttcctca taaccaaaaa
    42301 actcactctc tattagagat ggaggtatgg cagcacaatt tacagcaaca aaaggtgcat
    42361 ttttacgctt actatagtta tgtatacttt gacaaaatag ttctttacca actccagatt
    42421 ctccagtaat aatcatagga gtatcataac aagcatattt ttttgcaagt tctatacaat
    42481 cttttgtctt ttcactagca tgaattatat catcaaaagt gtatttagca gatagacctt
    42541 tgcttaataa gctccttctt attgtatgtt caaaagaact tatctccttg ctatcttgaa
    42601 atgttgaaac agctccttga atctgaccat caacaatgat tggaactcta tttgtaataa
    42661 tttttgtact ccctatattt tgtatttcac caatttgagg ttccatagtc tcaactactt
    42721 gtggaagaac tgtgtttggg ataacatcta caacattatg ataaagtgca ttttcttttt
    42781 ttataccaaa tattttttca gcactcttat taaataatgt tattttaaaa tttttatcaa
    42841 ctgttattat tccatcatgt acaaaatctg tcatagcttc tatctgtaat cttctttttt
    42901 gttcatcctt ggttgcttcg agtatttgtt ctgcttgttg aatggctcta agtatgtttt
    42961 cttctctaga ttcgattaat attcccttac aattaagtct cttaacaata tgtgcaacag
    43021 tggtatctcc tatatatgtg tttatacctt tctttctgta cttttctata gcatcataaa
    43081 tttcttcttc tttttcaatt tcaatcatag ttattttctt attcaatatt tcttctataa
    43141 tatcgaaacc gtagatgaca ttattaaatc caattattcc aaatggttcg ttggaatttt
    43201 ttacctcttt gtaacttttt ataatatcat aagcatctac tttaatttca actataggta
    43261 tattgtaagt agcttttaac atattgtaag ttccacctcg gcttatgata attctagtac
    43321 catgattaat acttttttca gcaagaggta taccttcttt tagattgcca aatacaacat
    43381 caatatttgt atatttgttt tttttaacta tgtgaattga tttttcatag gttcctttag
    43441 tgggagcaat aacgagtatt tccttcataa taattcctcc atatttcatc aaataaactt
    43501 aaatattatc ttatgactaa attttattag ttatatttta acattttact ttatatttaa
    43561 ttataaataa agtattttta aaaggaacat tataaaagac tgtatcaaag ttaactttta
    43621 gaattataaa gtttcatctt tttacagtct tttaatatat aatatctatt tatcaaatct
    43681 atctacttta aataatttca tatttttatt ttgtttgcca agatataatt cacttaacat
    43741 tatacctcct aatattgcaa agagtatacc atttgctcca taacctaagc aataccatag
    43801 attgttattt ttattatctg gaccaataaa acctaaatta tctaaagttg aagcaaaaca
    43861 accacaatat ttatattcaa cttcaatgtc ttttatatcc ttaaacatac ttttcaatct
    43921 ttgttctaaa atatcatact tttcattggc taaagtttca ttttctatat catcaaaact
    43981 tacatcttca ccacctataa ttaatcgatt gtctttagta gttcttagat aattatatgg
    44041 gtcacagtta tctctaatta aaatgttgtt tttccaagaa gctatgtttt taagtggttt
    44101 cgttgctata ttaaaagtat ttgacttagt tgcaaaattt ctttttgtaa ataaacttgt
    44161 attgtaccct gtagctacaa ttaatttttt accatgaact ttgtatccat acgatacttc
    44221 agcagtaacc ttatcatttg ataaatctac tttttttact tctgtatttt catatacttg
    44281 aagaccattt tttaaactta catcaatcaa atggtgacta tatttatatg ggtctaattc
    44341 tcgtcctcca ttctttgcta tcaatcctga ttttaaatca aagctaaaag ggtttgtgga
    44401 ttcatcaata tattcaacat caaatccatt ttcttttctt aagttatatt cttctttgat
    44461 agccttaact tcaagtttgt tggcagtata aagtagagta tctcttttgg cataatcaca
    44521 cttatttcca tatagctcta taaatgtatc taattcttca agtgctgaag tacaaaggtt
    44581 gtatgctttt agagcatctt ttagagtcat aacctctgtt aaatctatca aattgtcatc
    44641 taattcatac tgtaatagag aagttgtcac gctagtgctt ccatgtgcaa tccttccttt
    44701 ttcaagaatg acagacttta tattgttttt agctagatag taagcacaaa tacatccagt
    44761 tacgccacca ccaacaatta taacatcagt atcaatatca tcagtaaggt atggaaattg
    44821 tcttggaact ttattaatat tagtaaaaat aggatttcct tttacatatt cttgattcat
    44881 atacttcact cctaaaattt attatgtatg agtgtattat tttctatagc aaataatatt
    44941 atacatttta attatctagt tatatgggta tgtatagata aaatgtgata acattttagt
    45001 ataaaacata tgtataatat attcataatt accttatttt aagtaatata gtatataatg
    45061 tttgttaaca agtaaaaaga ttgaataaaa gttaattaaa aatttaaagt aggaggtaaa
    45121 tttatgcttt caaaaaatat agcttctaag gtattagaaa aatgtctaat tactggagga
    45181 gattttgctg agatttttga agaagacact ataaataatt ctattagttt aatagataat
    45241 aaagtagaaa atgcaatagg tggaagaaat tatggtatag gaataagaat atttaaagga
    45301 ttgaaaagta tatatgctta tacaagtgac aattcattaa atagtctgtt ggatgtagca
    45361 tacaaagctg ctgttgcttt aggtaaattg gaagatggaa aaagtgtaat attaaatgac
    45421 agtattaaaa taaataacat acataatata aaaatttatc caaattcaat aggaaataaa
    45481 gataaagtaa gtgttatgaa ggttgcatat aagagtgcaa aagaatttag taatgatata
    45541 tctcaagtaa gtgttagtta tttggataaa gaccaaaaaa tattaattgc aaacactgaa
    45601 ggtatatatg ttgaggatag aagaataaga actagactag ggataagttc aattgcatct
    45661 aagggtaatg aaaatcaaac tggatttgaa ggtcctggag gttgtaaagg gtttgaaata
    45721 tttgaagaaa tagacccaga atattatgca aaagaatcag ctagagtagc gcatactatg
    45781 ttgcatgcta aaaattgtcc tgcaggtaat atgatggtag caatagataa tggatttggt
    45841 ggagtaatat ttcatgaagc ttgtggacat tctttggaag ctacatcagt tgcaaagggg
    45901 aactctgtat ttgcagataa attaggtcaa cagattgctt ccacaaagat tacagctata
    45961 gatgatggta caataccaaa ctactggggt tctatgaata tagatgatga aggaaatcca
    46021 actcaaaaga atatactgat tgaaaatgga attttgaagt cttatatgat agataaactt
    46081 aatggtagac gaatgggaat gaatcctaca ggaagttctc gtagacagaa ctacaaattt
    46141 gcaccaactt caaggatgac taacacttat attgctgctg gagaggataa accagaagat
    46201 attataaagt caataccaga tggactttat gctaaaaaaa tgggtggtgg ttctgtaaat
    46261 cctgtaacag gagagtttaa ttttgtagtt tcagaaggtt acttaataaa aaatggagaa
    46321 atacaagagc cagttagagg tgctagttta attggaaaag gtagcgatat acttatgaat
    46381 atagatatgg ttgggaataa cgtaaaacaa gctcagggga tgtgtggctc atcatcagga
    46441 agtataccaa ctaatgtagg ccaacctatg ataagggtaa aagaaattac tgtaggtgga
    46501 agataggagg gataattgtg gaacttaaaa attttaaaga tatattattt aaaaaggctc
    46561 taagtgaagg ttttgaagag tgtgaaatat attattatac aggagaaaat ttaagtataa
    46621 atatatatga aggagaagtt gagaaataca atcttgataa atcttttggt ttatctttta
    46681 gaggtaaggt aaatggaaag ataggttatt cttatacaga aattttagat gataaagctg
    46741 ttgatatgtt gataaaaaat gtaaaagatg gagtaaacac tattgaaaat gaagatgtac
    46801 aatttatata tgaaggagat aagcactata atgatgtaaa gacttattct aaagagctag
    46861 aaaatttaga ggcagataag ttgattgatt tagctttaga aatggaaaga gagactaaag
    46921 cttattcaga taaggtggta aatttatcta aatgtactat atcttattct gtatcaagta
    46981 atggtatatc taatactaaa ggtcttaatt taagtaataa aactaatatg cttatagggt
    47041 ttgtagttcc tatcatagaa gacaatggac aaaaatatga tggaatagga tataatatag
    47101 caaattctat tgaagaaata aaaccttgtg agatagcaaa acttggtgtt gataatgctt
    47161 tatctaaagt aggtggtaag agtattccat caggtaaata taaaactata ttgcttaatg
    47221 aagctatggt atctttgctt agcacatttt ctgggatatt taatgcagat tcagctcaaa
    47281 aaggattatc tttattgaaa aatagagaag gagacatgat agcatctcct atagttacaa
    47341 tagttgatga cccactttta gaaaatggta tggcatctac tccttttgat gatgaaggag
    47401 tagctacatt taaaaaagaa gttgttttaa atggaaagct tataacttta cttcataact
    47461 taaaaacggc taataaggca ggtgtaaaga ctacaggaaa tggaataaaa tcttcatatt
    47521 catcacctat aagcatatat ccaactaatt tttatataga gaaaggagat aaatctttag
    47581 atgaaattat aaaggatata gatgaaggat tgatggttac tagctttgca ggacttcatt
    47641 caggtgcaaa ttcagtaaca ggagactttt ctttagctgc caaaggcttt tatatcaaag
    47701 aaggaaaaaa agtatttcca gtagagcaaa ttacagtagc aggaaactat tttgacctgt
    47761 taaaagatat tgaagctata ggagcagatt tagaatttcc aatgagtagt ataggttcgc
    47821 cttcagttgt tattaaagag ctatcagtag ctggaaaaga tgaataatta aaaagtaatt
    47881 ttgtggataa aaggtcatgt taattttaat taatatggct ttttattatt taagtagatt
    47941 ttattatcta agttatatga aaaagtcgtg atgcatacaa ttaatatcat acattaaatt
    48001 taaaggagga gatattatga gtgatgcaca ttatgacatg cacaagcgaa atggatattc
    48061 aagtgatgag ccatatccag agataaaagt tttaggtcca aataagtact atgcagaatt
    48121 attgatggat gactatgccg gagtatcaag tgaatttacg agtgtaaatc aatatctata
    48181 ccataatttt gatttagatg aaacgcatag agagttaagt gaaatgtgga taaatatatc
    48241 tataacagaa atgttacata tggagatatt agcaaagact ataagattat tgggtggaaa
    48301 tcctgtatat agaggttcta caagttcttg tggtgcatat tggaatggtg gttttgtatg
    48361 ttatggaaat tctatttgta acagattaaa actagatttg catttggagc atgtggctat
    48421 taataattat tataaagata taagtcttat tgaagaccct tatataaaag ctatattaaa
    48481 tagaataatc ctagatgaaa aacttcatgt aagtttattt gaaaaggcaa tagagaagta
    48541 ttgtaaataa atttgaaaat ttagttattc atcattttat tcatatatat aaaataacca
    48601 tcatacattt tcttgaaggg agttgctgtt gatatgtatt atgtatatgt gaatgatata
    48661 aacatagcag tatatgattt gaatccgagt gctaaaaaaa ctgtactttt tatacatggt
    48721 tggcccttag gacataagat atttgaatat caaacaaata tattgccaaa actcggatat
    48781 agaacagttt caattgattt aagaggtttt ggtaaatctg atgcaacatc aggaggatat
    48841 acttatagcc aattagcaga cgatatttat aaggtggtac atgctattgg attaaaagac
    48901 tttacccttg ttggtttttc aatgggagga gcaatcgtac ttaggtatat gagtttattt
    48961 aatggatatg gagtgtcaaa attggtatta gctgcagctg ctgcaccatc atttgtacaa
    49021 agacctccag aatttccata tggtatgaca cgtgaagatg taaataaatt gatagcacaa
    49081 gcctgtactg atagaccaga aatggtaacc gattttggag aaaaagtatt tgcatcaaat
    49141 ccaccagaaa gctttagaag atggtttaat gatattggtt ttagtgcatc aggtattggc
    49201 actattggaa ctgctgtatc tttaagagat gaagaattat ttaatgattt aaaatgtgta
    49261 agagtgccta ctggtatatt tcatgggaaa ttagatgaaa tatgtccgta tgaatttgca
    49321 gtttttatga atgaaaaaat agaagattca attttatata cttttgagta tagtggtcat
    49381 gctatattct atgatgagct taaactattt aatcaggaat ttttacagtt tttagaggaa
    49441 tagatatatt ttattatcac ttagaaaaag agtaatatta tgtgaaaaga tttaagctaa
    49501 attttatgat gttttttaca ctaaacaaat agggttttag aacttgtaac taagttctga
    49561 gaccctatta ttatatattc ctaaaatttg ttataattta ttccttatca ttcttaaaaa
    49621 tgtattaata tattaacgaa tttatattaa atttttgttt atattccaat aatgtcaaac
    49681 taaccgtttt agaaattaaa ttatatgtga aaaaaatagc ttacattatt ttattatgga
    49741 aaataatagt aaatggtaca aaatttgatt tttaagattt aaaacttttt taaaaagtgc
    49801 tacaatagac caaattatta ctttctatac tcgttaaaca ggaggtggga ctatgaaaaa
    49861 acataatatt ttatttgtat caactgatga caaaataaat atagatatat caaaacaatt
    49921 ggaaaatata tttggagaat tttgtaatat agataacttg gtatatgtaa ataggataaa
    49981 tattgaactg tcaagctatg agcttgtagt atgttcagac aatgatataa aggaatatat
    50041 acataataat attgataaaa atatacctat tgtaatagta catcgtacta taaatattga
    50101 aaatataaat cagataataa gtatagaaaa tgattctgat gttatggtta tagatgctta
    50161 taaagagtca gcagatgaaa ctgccaagat aattagaaaa ctaggattaa ttcatattaa
    50221 tctaatacca tattatccag gttgtgataa gtctaaatgt gagattggaa ttattacagg
    50281 aagcagaaac agcataccac aaaacataaa gcaaataatt gacataggtg ataaggtaat
    50341 tgatataaat acagttatag aaatctttac aaaactaaat atatctatag ataaattaca
    50401 tattattaag gaaaaataca atgaagatac agtaagtgga tataggtatt atacaactat
    50461 gaataaaacc atgaagagtt ttttggagat tatagatgaa ggtattgctt ctgttgataa
    50521 attaggaaaa tttatatatt gcaacaaagt attttctaat ctagttggaa tagaccaaaa
    50581 tgaaattata tctaataact ttatggactt atttagtgat aaggttgtca aaaaaatatt
    50641 ttttcaagaa gatgaagtta atgatgaagt agtaaattta aataacaaaa aactgataat
    50701 taataaagta aatgtttatg aaaataatga acgaataaag agtattataa gcattaaaaa
    50761 tataagtgca attcaagagc ttgaggacaa gattcaaaat aaacttcagt caaaaggttt
    50821 tgtatcaaag tatacatttg agagtgttgt aggtgagagt aaaataataa aagaaaaaat
    50881 taatattgca agaaaaatag caactacaga cttttctgtg ttgatacttg gagaaaatgg
    50941 aacaggaaaa gaaatatttg cccaggcaat acataatgaa tctctaagaa aaaacaagcc
    51001 atttgttgca gttaatctat cttctttgtc agatacactt attgaaagtg aactttttgg
    51061 ctatgatgaa ggaagtttta caggagcaat aaaaggtggg aaaatgggta tatttgaaag
    51121 agcacacaca ggaacaattt ttttagatga gataggtgat atatctttag atgtacagca
    51181 gagattgcta agagtattac aggaaaaaga agttatgaga atgggcggaa gtaaaattat
    51241 accaatagat gttagaatta tagctgcaac aaataaagat ttaaagaaaa aaattaaaga
    51301 aggttccttt agagaagatt tgtattatag gattaatgta ttacatatag agatacctag
    51361 acttagagaa cgtaaggaag atatacctct tataagtaag tattttttag atgaaataaa
    51421 tagcaacaaa tgttttacag aggaatcaat gcaagcttta acattgtatg aatggccagg
    51481 aaatgtaaga gagcttaaaa atttaattta ttatattgat actatagttg aggaagatag
    51541 agtagattac gagcatttgc cagaacaatt tagatttgaa aaaaacaata ctttagttaa
    51601 tgaaaatttc gattcaatta tcttagattt caaacaatct aatttctttg aggaaagtat
    51661 atgtatattg accagtatag aaacttggaa taataaaaat atattattag gaagaaataa
    51721 actgcaagag attttaaaag aaaaagatat agttttaagt gtagaccaaa ttagaaaaag
    51781 aatagataag ttaaagagcc atggtttact tttatctgga gtaaaaaaac aaggtagttt
    51841 tataactgat gaaggaaaga actttatatc atatgtaaaa attaagggag tgatataggg
    51901 gactaaaaag gcaaaacacc ctaaaaaaat ccctataatg gatagaaata aataaaatta
    51961 tctttaagat taagataatt caaaaatatt gaataaataa tctaagaaga ttatttttaa
    52021 taaaacagta gtaaatatca accttactac tgtttttatt ttttgcaaga tttattatac
    52081 aattaaaatt tatattttgg cacatcaatt gctacatagg aaaaatataa aaaattgtag
    52141 aacttggagg atgttgttat gaagtcagct tacaaaggat atgaagccta tagttattta
    52201 gaaaaaggaa aagatatttc atctattgag atgtgtaaag gagataaaag agttaaagag
    52261 taccttattg aattagatga tattcaagaa gcgaaggtta aaagtatagt ggatgaaaaa
    52321 atatttatat cattacatga acatccagta ttatttccag aacacctaga aagagatata
    52381 tttgaatata atagggaagg taaacaaaga tgcgcttatg aagcattatc aagaggatat
    52441 tatgatgcta tatttgataa tttaatggat ggtgtatgta cgataacatc aaattcaggg
    52501 tggaaatggg atgatatatt aatagattta ggcatgagac tatgtgattt agctcatcaa
    52561 gattttgtca taaagtgtga aaaagtagaa gatatataca gagctaaaag tgaaggtaaa
    52621 gtagcattga taccaacatt agaaggtgca gcaccaatag aaaatgaact tgacagaata
    52681 gatatactgt atggatttgg tataaggtta atgggtataa catacagcga atccaatgca
    52741 ttaggttcag gactaaaaga agagaaagat ggaggtctta caaattttgg gaaaaaagct
    52801 gttgaaagaa tgaataaaat tggaatggca atagattgct ctcacgttgg agttcaaact
    52861 acacttgatg taatagaata tagcaaggac ccaataatat taagccatgt tggggcaaga
    52921 agtttatgga acacaaagag actaactcca gatgaagtat taatagcatg tgctaaaaaa
    52981 ggaggggtta taggtgtaga agcagcacct catactacaa taacagagaa gaataaagaa
    53041 cattcaatag agtcatttat ggaacatttt gagtatatta aaaatttagt aggaatagac
    53101 catgtagctt ttggaccaga tacagtatat ggcgaccatg taaaattaca ctcagtacta
    53161 gctgctaaat ttgatataaa aaaaataaca ggaacaaaag aacatcccaa agtagaatat
    53221 gtagaaggtc ttgagaaccc aacagaaact tcaaaaaaca ttgttagata tttagtaaag
    53281 catggatata gtgatgagga aatagagaag gtactaggtg gaaatatact tagagtacta
    53341 aaacaggttt ggaaatagat atattagaaa tattaataaa atttgaggat ttatagggag
    53401 gttttataaa tggattattt aaaattagct aatcatccac ttttgtggat agcgagtaca
    53461 gtagcagtat caatagtagt ggtacaatcc cttatatttg ctataaaatc ttgcaaagtt
    53521 ggtaaaacaa tgggaataac agataaacaa ataaagtcag ctgttaagag tagtgctatt
    53581 tcagctattg ggccttcaat gactatattt gctggaatgg tatcgcttat agtaactatg
    53641 ggtgggccta tagcatggat gagattatca tttataggtt ctgtaatttt tgaatcaatg
    53701 tcagccggat ttggaacaga tgcattaggt ataactttag gttctcctga aatgacaaaa
    53761 cttgcattta caaatgcagt ttggactatg atattaggtt ctttaggatg gataatattc
    53821 acattactat ttggacataa actagataag ataaccaatg ttatatctag tggcaagaaa
    53881 tcatttatac caataatatc tctaggagca atgttgggtt catttgcata tctaaatgct
    53941 gatagggtgt tgcgttttga taatggaaca attgcatgta taagtggaat ggctataatg
    54001 gtaatattgt gtatgcttga aaagaagaaa aatataaaat ggttaagaga gtgggggctt
    54061 acaatatcaa tgtttagcgg aatgataata gcttcagtaa tataaggggg gagttttatg
    54121 agtaaagtaa aatctatata caatgaagaa tatttacctt ttatgataag gtatggaaga
    54181 ctaacactat ctttgggtat tatagcagca ttagttcctg gaataatttt gagctttgga
    54241 tttggtatta tgcctccaat atcagcatta ttagcaagta caatggcaat tgtcagtatg
    54301 agtgctccaa attacataat agaaccagtt tcttattcac caatcttagg tatcccagga
    54361 acttatatga gttttctttc tggtaatata tctaatatga ggctaccatg ttcaatagca
    54421 gctcaaaagg cagcagaagt tgaatcaggt acagaagaag gctcgataat atctacaata
    54481 ggaatagctg tatctatttt agtgaatata agtatactaa ctataggggt aattttagga
    54541 ggaagcgtat tatctaaaat tccagctgaa gtagtagaaa aattaaactt aattttacca
    54601 gctctatttg ggtcagtttt tggacaagta tttttacaag ataaaaaatt aggtctagta
    54661 gcaattgtaa tatctgtatt gactattata ttatcaaagc aaggtataat accacagtct
    54721 ctagtagttc ttatatgtgt atttggtact atattaattg caagagctat gtataaagat
    54781 aagcttagtg actaattaca atgaaataat agtgaatttt caaatatgaa atataataat
    54841 ttgattttca aatataaaaa ttacattaag attatttaaa aattggtttt taaggaggga
    54901 atattttgat atatgattta atcttaaaaa atggatttat aatagatggt acaggtaatc
    54961 ctggttttta tggagatata gcaattaaag acaacttaat agcaaaaata gattctaaga
    55021 taaatagcaa tacaaataaa gagattgatt gttgtggaaa agttataaca cctggattta
    55081 ttgaccctca tgttcatgaa gaaatagtag caatactaga tggtaaattt gaaaagtttc
    55141 taaaacaagg agttacaaca actataaatg gtaattgtgg acattctata acaccatatt
    55201 cttctgaaaa tgtgtatgaa tatatgtata aaaatggtct attacttgaa gaagaaaaaa
    55261 agtatcttat agataaaaat aaatgttgga ataattttac agaatattgt gaccttatat
    55321 ctaaaagtgg tatttctgtt aatatgggat tcttgttggg gcatgggact ataagatgga
    55381 gtgttatggg aggttctaag gatagacctc ctacagaaaa ggaaaaaaat gaaattacag
    55441 atataataaa tgatggaatg aaaagtggtg cttttggaat atctactgga ttggcatata
    55501 taccaagtaa gtatgctgat attgatgaac ttgttgatat tgcaaggcag attaaagagt
    55561 atgatggtat atatacatct catattagag attacatagg aagatataat gcagtaaaag
    55621 aagccataga ggttgggcaa aaaagtggtg ctagggttca agtatctcac ttaagtccag
    55681 ttgaaataga agcatttgat gatatattaa aggctaggta taatggtgtt gaaataatgg
    55741 ttgacacagt accaagaagt tctgggcatt gtatgaagaa aaaaagagta attcaattta
    55801 ttatggcaat atcatctagt ctatttgaat taggtataga tggggtaatg gatgctctta
    55861 gaaatgaaga gggaagaaca cttatattaa aagaagcatt tatacttgga gataggggga
    55921 gtataatact tctaaacact aaagatatta atatggaaaa gaaatcaata cgtgaaatag
    55981 ctacacaaaa aggaatagat gaagacaagt tattactcga tttactttta gatggagacg
    56041 aagaacttat cttttgttta ggaggaatgt atagagctga tttcccagat aaactacatg
    56101 atgataaaat aattgataat ccatttgtta tggttggttc agattgtttg tttagtgtgg
    56161 gtggggatat gtcatggttt gaactacaaa gaagaggagc ttttccaatt ttcttcaata
    56221 tgtacagaaa gtctggtgtt agattggaag agattgtaag aagagttact tcattaccag
    56281 ctaggcaatt taaaataaaa aatagaggta ttcttaaaga agggttgata gctgatatag
    56341 cagttattga catggataac tatagttatc ctaggtcaga agatattgat ttttcaaagc
    56401 cacaattact agccaatggt gttgaatatg taattgtaaa tggaaaaatt gcgttagaaa
    56461 atggagagat tactgagaat aaatgtggtg aagtattgaa aagataaggt tttaaaaata
    56521 ataggattta gaaagtaaat aaatatctaa gtaagtaaag acgaagtttg agatttattt
    56581 aaataaaaat catgcttcgt ttttatttat agtattaata tttattttaa taatcagata
    56641 atatttgtac tttatagtga aaaaattaat atttttaatc attaaattat gtaaaaaatt
    56701 ggataaatag ataactaaat catttgagaa aagattttta gaaataaaaa atgataacta
    56761 aataacccct ttaatattta tcaaatagcc agtcataaat attaaagggg ttatttagtt
    56821 tataaaaatt atttgtaata aagtaggata tattaataaa tatgatagaa tatatattat
    56881 aaattaaatt tataaatata aggggggaac tttgagttct tatagatttc ttacattata
    56941 agaaccaata ctttatgcgg gagttattaa aagtaacact tatagtaatg cttgttttga
    57001 taaatgcttt ttttgtagct tgtgaatttg ctatggtaaa acttcgtagt tctaggattg
    57061 ataccatgat agctgaaggt aataataatg caaaaagatg taaaataata aaagacaact
    57121 taaattccta tctttctgca tgtcaacttg gtataacact ttgttcactt gcattaggtt
    57181 ggatgggaga atctacagtt aaagagttaa ttttaccaat agtaagtgta tttaatctta
    57241 gtgaaagtat tatatatact atatcaattt ccatttcttt tttaattata acaatgatgg
    57301 aggttgtaat aggagagttg gttcctaaag ctttagcact ttataataca gaaaaaataa
    57361 tgttgagtac atctttttta ttagtaggat tttataagtt aacatatcca ataatatatt
    57421 ttttcaactt aagtactgat ttatttctta aaccatttgg atattcacaa gctgatgagg
    57481 ttgatgaacc ccatacaggt gacgaaataa gactattagt agaagaaagt tataaaagtg
    57541 gacttataga tgaatcagag caaagattag ttgataatat ttttgaattt gaagaaaaga
    57601 aaattagaga gataatggtt cctagaactg atatggtatg tatatatgaa agtgattctg
    57661 aagaaaagat attagctatt ttaaaagagg aaggtgttac aagatatcca gtatgcagaa
    57721 aaaataaaga tgatatatta ggttttgtac atataagaga tttatacaat caaaagataa
    57781 atgaaaataa aattgaacta gaagaaatat tgagagatat tatatatata tctgaaaatt
    57841 taactataga taaagctctt gagagaataa gaaaggaaaa acttcaactt gctatagttg
    57901 tggatgaata tggtggtaca tctggtgtgg taacaataga agatatacta gaagagatag
    57961 ttggagaaat tcaagatgaa tttgacaaag aagagactca tattaagaaa ataggagcag
    58021 gttcttactt agttgatgga actgaatcta tcaactatat taataagtat tttggacttg
    58081 atatagagca tgatggattt gacagtatag gtgggtggat atcctatatg cttggttcaa
    58141 atattaaagt aaaccaaagt gtaacttttg aaaattacaa ttttacaata ttagaattgg
    58201 ataaattgag ggttgtaaaa ttaatcataa aaagtgtaat ataattatat caaaaaatat
    58261 tggaggaatt gtatgcaaaa agtagaagga attatttttg acatggatgg agttttgttt
    58321 gactcagaga gaatttctct tgaattttgg atggagacgt ttgaaaagta tggatatact
    58381 atgactaagg aaatttatac atcagttatg ggaagaaatc gtaaaggaat aatagaaggt
    58441 cttacagata tatacgatag ttctgtacca ataatagatt tatatgacga aaaaactaaa
    58501 aatatgattg aatttatgga gaggaaggga gctcctatca aattaggagt caatgaacta
    58561 atctcttttt taaaagaaaa tggatacaaa atggctgttg caacatcaac aaagagagaa
    58621 agagcagtaa agagattagc taaggcaaat ttaaaagatt actttgatgc tatagtttgt
    58681 ggagatgatg ttgtaaactc gaaaccaaac cctgagatat tcctaaaagc agctaaaaag
    58741 ataaatgtta atcccaaaaa ttgtattgtc atagaggatt cgcctatggg agtcgaagct
    58801 gcatacaatg gtggtataag atgtataaat gtaccagatt taaaagagcc agatgagcaa
    58861 attaaatcac aatcacataa gatacttgaa aatttactgg aagttagaga atacctaaaa
    58921 agtttaaact ctaaagaatg tcacaatcta taatataaag tattaattaa ataaattaaa
    58981 tataatttct ttgatttaga ataaatccat gaatatgaga aaaaataagt ataaacagct
    59041 aggaggaata ttcatggata atgtaggttc tctattatat tttttattta attttttctt
    59101 gtatggtttt ataggttgga taattgaaaa cttatatagt tattataaac aagggcattt
    59161 tcaagaagat ggatttttaa atggtccatt taaaccaatg tatgcaattg caatgtcgat
    59221 tataatagag gtctcaagat ttattgaccc caataatata tttgcattgc ttttattatg
    59281 tctagtagtg ccgacagtag tagaatatat tacaggaata cttatgaaag tatattttaa
    59341 taaggtctat tgggattatt cagattataa gtacaatagt agaggaatag tatgtctaaa
    59401 gttttctgta tattggacta tattgacatt tattggagtt agatattttc aagtgtatat
    59461 agttgatagt ttatatagtc ttataatacc ttattggcca attgttgtaa ctatactttt
    59521 agtaacattg tttgtggatg aaattcttac tataaaattt ttgaggggaa ataaagatat
    59581 agtagaaaga taactttaaa aatataagtt gaatttagat tgtagttaaa agaaagctat
    59641 gttaaaatgg tgaaatcatt taaaattagc tttctttttt atttgataaa attattttat
    59701 aatatatcta taagttgtaa agttttttat taaaattaaa ataaagtgta gaaaatgggg
    59761 agtgatttat gatgggtaaa ataagatttg gtattgttgg gacaagcaat atagcaaata
    59821 tatttctaag agctgcatct agggttaaag actttgaatt ggttgctgta tattctagaa
    59881 atttagaaaa agctagagaa tttggaactc tatatggagc aagtattttt tttgatgatt
    59941 tagaacaaat ggctaaatcg aaggatatag atgctgtata catagcttct ccaaatgcat
    60001 tacattcaaa gcaaaccatt acttgtttaa aacacaaaaa acatgtgctt tgtgaaaagt
    60061 cgttagcatc taatttaaaa gaagtcaaat caatgataaa aacagccaaa gataataatg
    60121 tattgcttat ggaagctatg agaattacat gtgttccaaa ctttaaagca gttaaagaaa
    60181 acttatataa aatagggaaa ataagaagat tttttggaag ctattgtcag tattcttcaa
    60241 gatatgataa atataaaaat ggaattatag aaaatgcctt taaaaaagag ttgtcaaatg
    60301 gagctttaat ggatatagga gtgtattgta tacatcctat ggtgaattta tttggtgctc
    60361 caaaaactgt aaaggcagtt tctcatatac ttcaaactgg agtggatgga gaaggttcag
    60421 ctgtatttca atatgatgat atggatgcga taattcagta ttctaaagta gctgattctt
    60481 atataccatc tgaaatacaa ggagaagagg gaagtataat aattgaaaag cttaatctat
    60541 ttgaaaaagc tattattaaa tacagagatg gaagagaaga agatatatct attccaaaag
    60601 aaaaagcaga ggaaaagcct agagaaatag aaggaatgta ttatgaactt gtagagttta
    60661 taagtcttat aaataacaat aaaatagaat caaatataaa ttctcatgaa aattcaataa
    60721 tagtaatgga aattatggat gagataagaa gacaaagtag tattgtttat ccagctgata
    60781 gtatatagtt tatattagaa aatataagaa tttataatat atattcttaa ataaatttaa
    60841 ttttaagtta aggtaaggcg tatacttaac caagtgttaa aatgtcaaat tataagtatg
    60901 aaaaagtgct aaaaagaaat ttatttttgg cgtttttttc ttttttttta caattttgta
    60961 acagtatcaa aaaaagtttt gacgatttta ttacaatttt gtagttgaat atacatatca
    61021 aaactaatat gattaataat aacataaatt tgaatatttt tagaggagag aaaatatgag
    61081 aaaattgata tactttatta caccttttat aataggcgta gtatttttat ttgggttaga
    61141 caaatttctt gattctaaaa ctgatgaact tttgagggag aaaaatctac ttccaattat
    61201 ggatgatact ttaagtgata taaaagataa aggggttaca gcaaataatc attttttaag
    61261 agaaaaggat attatgattt tggggtcatc agaacttagt aattcaacaa aacaacatcc
    61321 aaagtactat tttaatacaa ataggagtaa aaataaggtg tttgcaattg gaagagccta
    61381 tactcagaca ttacaagatg ctgcaatatt aggaagtatg aatcctaata ttgataataa
    61441 gaaagttgtc ttgttaattt ctatgcaatg gtttatggaa aaagacggag tcacaagtca
    61501 ccattatcag tctagatttt caccaataca attttatcga tttttagata atccaaaaat
    61561 atctaaacaa aataagattg aatatgcaaa aaaatcaagt aagttattat ggggaagtga
    61621 tgagtataaa gcagaagcat tatatgctaa gctatatgag cctaagacat ttcctgaaaa
    61681 agctgaaaag gtgcttttag agccttattt tcaaggaaga aagtattgta tagctcttaa
    61741 agaaaagggt attctttata aacgattaat taagctagat aaaaagagag caacaaaaag
    61801 aaaaagacca ataaattggt catatgagag aaagaaagcc attgaagatg ctaaaaaaag
    61861 agttggtaaa aatccactaa atattgataa gtactattat aaagagcatt ttaaagatgg
    61921 tatagagcaa tacaaaggaa gagacaaaga tgtaaattta ttaacatcta aggagtttga
    61981 aaattataaa ttgatgctaa atgtatgtac tgacttaggt attaagccag ttgttgtatt
    62041 aatcccaagt atggataaat tctataattt gactggtatt tctgaaaaag aaagaaatca
    62101 gtactacgat aaagcacaaa aaatagcaga aagcaaaggc tttgaagttc taaaccttaa
    62161 agataaaggg tcagataagt attatttaag ggatgtaatg catcttggta cgaaaggatg
    62221 ggtagatgtc tgtgagagat tatttaaaat atttaaagaa caataaagat ttgttaacta
    62281 gtatttgttt aactatggtt ataatattgg cgataggagt tctaacattt actccattta
    62341 aagaattgcc atttatttat aacggatttt aaaggagcat tcttatatga aaattattga
    62401 aggaataaaa aaatattcaa atacagatag aacagcacta atgtgtaatg gagataaact
    62461 ttcttataaa gatttaaatg aatattcaga tgctatatca gtatttctaa aggatgtata
    62521 caaagaagaa gatactccta tagtaattta tggaaataaa gaaaacatga taatggcatg
    62581 tatgatagga gctttaaaat caggcagagc gtatgtgcct cttgatatta gttttccaat
    62641 tgatagagtt tttgaagtca ctaaagagat aaaaccaaag gtattattta actttagtga
    62701 tgaaagaaat tttggagata tcaatgtaat tgatatggat aaattaaatt atataataaa
    62761 tgaatatcag ggaaaatcat tagataaaga aaactgggta aaagatgatg aaaatgcata
    62821 tatactattt acttcaggaa gtacaggaaa gccaaaaggg gttcaaataa gttcaaacaa
    62881 tttagatagc ttttcagatt ggataagccc atatctaaac atagatggaa gtgaaaaagt
    62941 aataatgaac caaccagcat attcttttga cctttcagtt acaacaatat accctggtct
    63001 tatccatgga gctacattat tttcaatatc aaaagatgta ttagcagact atagagaact
    63061 atttagacaa tttagtatct cagatatagc tgtatgggtg tcaactcctt cttttgcagg
    63121 agtatgtata actgaaaaag agtttaatag taaaatgctt cctaaccttg agtcaatgat
    63181 attcatagga gaagcacttt caaaaaatct tactaaagaa cttatgagta gatttccaaa
    63241 cacaagaatt atcaatggat atggaccaac cgaggctact gttggtgtaa gtgtaaatga
    63301 tatgactcaa aaggctatag atgatgaaaa aagtcttcca gttggatacc ctatgtcaaa
    63361 ttgtaaaata aaaatacttg atgaagatgg aaatgagctt aaagaaaatg aaaagggtga
    63421 aattataata attggaccat cagtttctaa aggttacttc aataataaag aaaagactga
    63481 tgaagtattt ttctatgatg aaatagatgg tgtaaagtgg agagcttata aaactggaga
    63541 tatgggatat cttttagatg gaaatatata ttattgtgga agaaaagatt ttcagattaa
    63601 attaaatgga tttagaattg aaatagaaga tatagaaaat aatttgagaa aagtacataa
    63661 tgtaaaaaat gcagtagttt taccagtata taaggacgaa aaaattgctt acttaaaagg
    63721 tattgttgag ttaaatgaaa agaatgattt aagtaatatt aaaaatggga ggataataaa
    63781 aaaggaactt ggaaagtata taccttcata tatgattcca agaaatattt caataatctc
    63841 tgagtttcca acaaatatca atggtaaaat agacagaaag aaacttatgg aggaaattta
    63901 atgatttttt cacaatatgg agattatttt tatctttata tattattatt aacatcaata
    63961 ccatcagtaa ttttaggtct aatgggcaag aatataaagt attatggtat gttggcaagt
    64021 ttgtttatga tattcttaat agtaggaatt gatgtccaac taaagtactt ggtaatattt
    64081 attattcttg aaataataat agttaaagga tatgaatatg taagaagaaa aactaaaaat
    64141 aaatacatat attggggatt cttgtttgca tcaatgctcc caataataat aaataaaata
    64201 tctccagtta cttcttttgg aataattgga tttattggaa tatcatactt aaatttcaga
    64261 actatacaaa tggttattga aatttatgat ggagctataa aagaagttaa aatttcaaag
    64321 atgctttatt ttatgttatt ttttccaact ttaagttctg gacctattga taggtcaaga
    64381 agatttgaac aggacttgga aaaacaaatc tctagaaaag agtatataga agaatactta
    64441 ctgccaggaa taaaaaatat tgtcatggga gtaggttata agtttgttat agcatttttg
    64501 ataaatacat attgggtatc aagaatacct aaagatatga gttttataaa tattttaagt
    64561 tatatgtacg catatagttt atacctgttc tttgattttg cgggatatag tttatttgct
    64621 ataggtacag ggtacatatt tggaatacaa gtacctataa actttgacaa gccatttatc
    64681 agcaaagata tgaaagagtt ctggacaaga tggcatataa gtctttcaag atggtttgga
    64741 gattatattt tttctagatt tgttatgtca tcaatgagaa agaaaagatt taagaaaagg
    64801 actactgctg ctcatgtggc tcagatgata accatgataa caatgggatt ttggcatggt
    64861 ctaacttggt attatgttgc ttatggtgta taccaaggat tggcacttgt gttaactgat
    64921 atatatcagc gaaaatctaa attttataaa aaacataaaa aagataaatg gttcgagaga
    64981 gtgcagattt tcattacatt ccatattgtg tgttttggat tgctgatatt ctcaggttat
    65041 ttagcttaat tttaaggagg aaaatttatg caagaaacag ttatagaaat atttgaagat
    65101 gtattaggaa ctgatgagat aagagaagat ttagacctta atttatttga gacggaactt
    65161 ttagactcat tagctataat tgaagtttta cttgaaattg aaaatagatt agggatagag
    65221 cttcaaccaa ctgatttaga gagaaaagat atgtctactg taaataattt agtaaaattc
    65281 ttggagacaa gaaaataaat tagtagttag actttaaata ttaatttata aaataaaatt
    65341 ttacaaagtc catctgatac taatatttga tggacttttt taatgataat acaaagtctt
    65401 ttgaaaataa ctttaattaa gtaaaaaatt taatacataa atatgatttc ataaatctta
    65461 ggtatcattg taatattata ggagaaaaat atattatatt taggaggaaa atgaatgtct
    65521 ttaaattcga tagatagaaa aaaagaaata cttaaattat tagattcaaa agggaaggta
    65581 aacactaaag aattagtaaa aagattagaa gtatcatcag aaacaataag aagatatttg
    65641 gaagaattag aaaatgaaaa taaattaaaa aaggtatatg gtggtgctat aaaaataaat
    65701 tatggagtga ttgaaccaga acatataaag agaaacaata ctaacctaga taaaaagcaa
    65761 agtattgcta aatatgcagc taaatttgta aatgacaatg agtcaattat catagatgaa
    65821 ggtactacca atttgcagat tgtagattat ataatatctg taaacaattt aaaaattatt
    65881 acaaactctt atccagttct atcaaaattg atttcttatg agaatcaagg tttgtttgat
    65941 ggagaagtta tatttattgg tggaaaagta aatttaaaac accaaaggac agcatgtcca
    66001 atgtcaatag atactatgaa aaacttatac gtagataaag cttttatatc tagtgaaggt
    66061 atacttgata gttttggaat tagtagtata gaccaaaata aggcattgtt gtcaaaagaa
    66121 tatataaaaa attcaaagga aagttttgta ttatgtgata gttctaaaat aggaattgct
    66181 agtatgtata agatagcaga tttagaggaa ttagattttg ttatttgtga tgtagaacct
    66241 ccgaatgaat ggaaggataa gttaagtgag ataaatataa catggataga agcaaaataa
    66301 acccttagtt ttatataata caactatgct caatacaact aaattcataa aatatagtca
    66361 gttcatagat taagattaga aagtaaattt tagattgtaa cttaggattt tatgggaata
    66421 tgatacaaaa taaaaacaac taaatacaac taaaaacaga aatttaatat atatttaacc
    66481 taaatatgat gtataattaa catatgaaag ttatacttta aaagtaaaaa caattaaaaa
    66541 cacaaaaatt ctaaaaagaa tctatggagg ctataaatat gaaaaagata tatggagaaa
    66601 aaataaaagc agtagtattc gattgggctg gaacaacagt agattatgga tgttttgcac
    66661 ctcttaatgt atttatagag atatttaaaa gaagaggtat agatgtaaca atggaagaag
    66721 caagaaaacc tatgggaaaa ttaaaaatag accatataag agaaatgtgt gaaatggata
    66781 gaataaagaa tatttggtca gataaatttg gtaaagtgcc aactgaagat gatgtaaatg
    66841 aactttatgc tgaatttgag ccaatgttat ttgagacatt agaagattat acgactccaa
    66901 ttcctcatgt tgttgaaact attgaaaagt tgagaaaaaa tggattaaaa ataggttcta
    66961 caacgggtta tacaagagag atgatgaaca tagttgaacc aaatgcagca aagaaaggat
    67021 actcacccga ttttcttgta acaccatcag aagtatctca aggaagacca tatccttgga
    67081 tgtgctataa aaatgctgaa gctttagggg tgtctcctat gagttctatg gtaaaagtag
    67141 gagatacaat aagtgatgta aaagaaggcg taaatgcagg aatgtggagt gttgctgtaa
    67201 taaaaggttc aagtgagtta gggcttacac aagaagaagt agagaacatg gataaggaag
    67261 aattaaaagc taagatgagt atagtttcaa agaaatttaa agaggcaggt gcacattttg
    67321 taatagaaac tatggctgag ttagaagata tactaataaa aatagagaat gaaactatta
    67381 aatcagattt tgtaccagaa aatgattaca tattacttac accaggacca ctatctacta
    67441 ctaaatcagt aagagcatct atgttaaaag attggtgtac ttgggatatt gaatataata
    67501 acctagtaca agatgttaga agaagattag tatctctagc aacccaaaat acagataaat
    67561 acacaagtgt attaatgcaa ggaagtggga ctttttcagt agaagctata ataggaagta
    67621 ctatttcaaa agatggtaaa cttcttgtaa ttgcaaatgg agcatatgga aagagaatga
    67681 aagatatatg taattatctt aacatagaat ttgttgactg cacttttaaa gatatagaag
    67741 cagtggattt aaatgtagta gaaaatttat taaaagaaaa caaggatata acacatatat
    67801 caatggttca ctgtgaaact actacaggta gattaaatcc tatacaagag gtagggaaac
    67861 ttgcaaaaga atataacaaa atttatatag ttgatgctat gagtagtttt gggggaattg
    67921 agattgatgt tgaagatttt aatatagatt ttttagttag tagttctaac aaatgtatac
    67981 aaggagtacc tggatttggt tttataatag ctaataaaga gaaattatct aaatgtaaag
    68041 gtatagctaa atcattatct cttgatgtgt atgcgcaatg ggagactatg gaggaaaata
    68101 atggtaaatg gagatttacc tcacctacac atgttgtaag agctttttat caagctttat
    68161 tagaattgga agaagaaggt tctgttgaaa aaagatatgc tagatataaa gaaaatcagt
    68221 ttacaatagc ttcaagatta aaatctttag gatttgatac tttggtgaat gataatgctc
    68281 aatcacctgt aataacaact ttcttatatc ctaaaaatgc aaagtttgaa tttatggaat
    68341 tttatactta tttaaaagat aatggatttg ttatctatcc aggtaaattg actgatatag
    68401 atacatttag aataggtagc ataggtgaag tttatccaac tgatatggag agactagctg
    68461 atgtaataga aaaatttatc aatagataga agaagatagt gtcttgtagg ttacagaata
    68521 gtgtggaaag cccactcctt taggtgtgtg agatgatagc acaaacagtg tataaaaagt
    68581 attgacagta gaatttaaag atttatattt tagaagttta tacaatgaat atataaagat
    68641 tgagtaatag ggatatattt tatttaaacc acaatctaag aaattagatt tatagtttaa
    68701 ataaagaatt tccctattat ttttatgcct atttatagaa aataaatgat agttgcttta
    68761 ttaagtatta ttatcatact tgacaacgta acaatgtttt gttatattag gtttagagat
    68821 aaaatacggt aaagaaagga tatcattatg aatgaagaat taagttcact aagatttgat
    68881 ggtgttggaa aatgtaaagg tggaattttt gataatgtta atatatcagg aacaggcaaa
    68941 atagaaggaa gtgtaaaatg tagtaaattt gattcttctg gttcagcaaa agtttttggg
    69001 acaacagaat gtaatgaatt ttttacatct ggtttaagta aagtagaagg aaacatactg
    69061 gcatcaaaag ttgagatatc gggacttctt agatgtacag gaaatattaa ttctgttgaa
    69121 attgatacta gtggaattat taatgtagaa ggaagtataa aatcggatat tattcatgga
    69181 gaaggatatt taaaagcaaa tgagaatata gattgtgaaa atatcaattt aagtggaatc
    69241 ttggagtgta atggattttt gaattgtgaa gaagttaata ttagtttaaa tggaacttct
    69301 aattttaatg aagttggagc aagtagtata aatataaaaa aggggcatgg agattattgc
    69361 aaaaaatttc gtatgctaga aaaaaagcat atcaactttg aaaaagtgtc ttcaaattta
    69421 ataagtttag gtctattatc aattagaaag tatacagaaa gtaaattgtt tgcaaatatt
    69481 atagaagcag atgaaataag cttagaaaat agtgaagtca aagttgtaag aggaaaaaat
    69541 attaaaatag gcaagggatg ttatgtagaa agtttggagt acagtgaaag tatagagatt
    69601 gatgaagatt caatagttgg tgaaataaag aatataagtg aaaaaataaa attaaagaag
    69661 gataagtaat aagtaggttt aaaaataaaa tttaaaatga ggtaataata tggaaaaagg
    69721 gtctataaaa atacttggag aaggctttat aagtagtggt gagtatgaaa atataaaaat
    69781 cgtgggaagc tctaaatcaa aaggaaatgt taaaagtaac gaagtaaaag tccttggaga
    69841 tgcaaaattt gaaggtgaca tcaatataaa aaattttgtt gttaacggaa aaactattat
    69901 aagaggcaat cttaaagcag agcgtgtaag agtgaatggt caacttaata tagagggaga
    69961 tgcagaaata gatgacttag ttataactgc tcaacagaaa gtggatggca aacttaaatg
    70021 taataatgtt acaataagag gacaattaag tgtaaatgaa aatatgtatg cacaagatat
    70081 aaaaatctat ggcgaaatga gaaataaatc aaatatagaa tgtgaagata taaaggtata
    70141 tggagcaata aaatgtgatg gtcttttaaa tggagaaaat atatatgttt attcaggagg
    70201 aggttcttat tgtaaagaga taggggcaac taatataaaa ataggaagaa gcaaagatgc
    70261 tttttcatta attaaaatca ttaatatttt ttcaggaaag tttaaatgta atttgataga
    70321 gggagatact attgaattag aagatgcatc aataaaagat atacgaggca aaagcatatc
    70381 tctagtagat aattgtgacg ttgtaaatat tgaatacagt gataatttat cagtttcaga
    70441 taattctact gtaaaaaaca gtataaaggt gggctagaaa agttatggaa gaattaatat
    70501 ctaagaaaga tttattgagc aaaactaata tatcttatgg tcaattatat agatggaaaa
    70561 gaaaaaacat aataccagag gaatggttta taaaaaaatc agcttttaca ggtcaagaga
    70621 ctttctttcc aagagataaa atactagaaa gaatagagtt aatattgtct atgaaagagg
    70681 agacttctct tgatgatatt gcaaatatgt ttatgaaaaa ggatattaat aaagaatttg
    70741 acattgattt tattctcagt aaagaagtta tatgtaatta taccaaagaa atatttcaaa
    70801 atttatataa aaaagagcaa agcataggta aaaaagaact gcttatattg agcataatag
    70861 agaagttttt agttaaatct ataataactt ttgaagagtt aaaattgata gtgaatataa
    70921 tagaagaaaa ttttacatca atatacaatg aaagtggaaa gatttatttg tttagaaagt
    70981 ttggagttcc attcgtagta ggatgtctgg attataaaaa agtaaagttt gaaaaagatg
    71041 tagttaagat tattgagatt gacttgacaa aagaaataaa tgatataagt ataaagttat
    71101 catagtgtat tatcttatat aatgtattat aataatatac ttaaaataca ctttatttaa
    71161 atatttagtt taaagataag attttatgtg agtgtgtaaa agttaaagat agatttaagt
    71221 aggttatagg gattagtaaa taataaaatg aaccatgatg aattactata aattgtattt
    71281 aaactacatt ttctacttat agtaatatca atggttcatt ttattgttat taagataata
    71341 cagtatttat aaaaatactt gatataaata tagtaaattg tttaaataga attattgcct
    71401 taatttattc aaataatgag tttttaaaat ctaagaaata tccttgtgga tgaagacata
    71461 caggacaagc ttttggagct tctttaccta tatgtatatg gccacaatgt gtacatatcc
    71521 attgtatatc ttcatttctt ctgaataaag taccttcttc taaatcagta gcatatctac
    71581 caaatctatc accatgaact ttttctattt cagctatatt ttcaaataac ttagctatag
    71641 attcaaatcc ttcttcacgt gctgtttttc caaagttttt atatacatca tcccactctt
    71701 gaagctcatt atgttgtgca gctttaaggt gttgtgctgt cttgtcatat aaatctacag
    71761 ggtatgctcc tgatatactt atattttcac cagcaaattc ttttaattta gaaaagaatt
    71821 gttttgcatg tgatttttct tggtcagcag tgtaattaaa taaagactct attatatata
    71881 atccttcttt ttttgctaca gatgcagaaa tattgtatct atttctagct tgactctcac
    71941 ctgcaaaagc tcttaataaa ttttctttag ttttactatc ttttaaattc atattctacc
    72001 tctctatcat aataaatttt tacaatattt gattcttttt atttattatt ccaataggag
    72061 atataattat gctcaattta gtcagcattt ttaaaattat cattaatttt ttttaaaatt
    72121 ctaagaaatt cttgtttttc attttctgta atattatggt atgctgtctc tttaacttgt
    72181 gttgagatgc tattaaaagt atcttctata agcagtgcct tttttgtaag ctttatatac
    72241 gtgatacgtt tgtcatttgt acatttttgt ctttctaaat atcctaggtt tataagttta
    72301 ttaaccaaca ctgtaacagt ggatttatct tttcctattt tagctgcaat ttctttcatt
    72361 gtaagtattc cattattttc ataaagtgca gttaaaatat ttccatgagt aggtattaac
    72421 tcacctaaac catttttact gagtttattt tcaatgaatt taatcatact agcctttgtt
    72481 ttacttatga aatgtacaat atatttatct tccataaatt attctccaat ctttaatcta
    72541 tttaaattag tttgacataa aactatttat aaactataat tagtttaaca taaaactaaa
    72601 tgtattggga ggaaatttat gaataaaaaa tttaaatcac tatatattac agaagaagaa
    72661 ggaaatttta gaagaaatat agttgaaaga gaagtagata cattgccaga aggcgaagtt
    72721 ctaataaaag taaaatattc ttctttaaat tacaaggatg cactttctgc aaatggtaat
    72781 aagggtgtta cgagaaagta tcctcataca ccaggaattg atgcatctgg tatagtagaa
    72841 tctagtagtt gtgatgattt taaaattgga gaagaagttt tagtaacagg ttatgacttg
    72901 ggaatgaata cttctggtgg tttttcagaa tacataagag ttccttctag ttgggtagtt
    72961 aaacttccta aaaatctttc actaaaagaa gcaatggatt atggtacagc agggtttaca
    73021 gcagctttat ctgtgtataa atttatagat tctgtagaca agaatatggg agatgtatta
    73081 gtcactggtg gtactggagg agttgctgta attgcaacta aaatattgat taaattaggt
    73141 tattcagttg tagtttcaac aggaaaatta gaagaacaaa aagaagtatt actaaactta
    73201 ggtgttaaag atgttataca taggtcagaa gtggatgata actcaggaag acctctgctt
    73261 agaccaagat gggctggagt aatagataca gtaggaggaa atactctagc aacagcaata
    73321 aagacaacta attattgtgg agcagtaaca acttgtggta atgcaggagg agttgatttt
    73381 acaagttcag tatatccatt tatattaaag ggaattactt tatatggtat agattctgtg
    73441 gattgcccaa tgaacttaag attaaaaata tgggatttat tatcaaatga atggaaatta
    73501 gatgatttag atgatatggt aaatgtagta tcattggaag agttaaatga tagtatagat
    73561 tcaataatgg caggaaaaca tgttggaaga acagtagttg atttagaaaa aatataggtg
    73621 aataaattta taattaggat tataggtttt aagcaaaaat gagatacttg aaatttactt
    73681 gtgagtatct cattttttta tgtaaaaaga tttatgtaga tgtttgtgta aaaagattat
    73741 tcatgaacaa ttaattcaaa tacatctggt cttgaatagt gaccttctga atcaaaatct
    73801 agtctactaa gtactatttt ttctaggtct aaatcagcta ttagcatttc ttctttattg
    73861 aaaataggac ctgctacata ttttccaaaa gggtcaacta tacaacttcc tcctggacac
    73921 ataatttctg gttctgcatc tagctcttta tagtagttaa ggtcagttgg atacatattt
    73981 ttttcaacat attgattgca tccaattaca aaacatcttc cttctaaagc aatatgcttc
    74041 atagttgctt gccactcttc tcttgaatct gcagtagggg ctatgtaaag ttttacaccc
    74101 ttagcataaa gagctgttct agctaatggc atataatttt cccaacaaat caacgaaccc
    74161 atttttccat atggagtatc aactactgta agagtacttc catctccttc tccccaaata
    74221 catctttctg ttcctgtagg tttaagtttt ctgtgtttac caattagctt accttctgga
    74281 gagaaaaata agtttgtgca ataaagggta caatttatat cattaccatc tctttctgtt
    74341 atacccattg atagatatac tcctgcttct tgtgctgctt ttcctaataa atctgttgta
    74401 gcactaggaa ctggtacaga attatcatag tatcttttcc aatcttctct accttccatt
    74461 gttctacttc caacaacaaa tccaaatgaa agacctcttg gatatgcagg tatgaatgct
    74521 tcagggaaaa ctacgatatt tgcccctttt ctaccagctt ctttaattaa tcctaatgct
    74581 ttttcaacag ttttttctaa atccattatg actggtgacg cctggacaac agcaattctt
    74641 acatttttat tttccttgct cataaaaaac ctcctaaaaa atatttaaat tttttgcatt
    74701 gaatagatta catgagatgt tatttgagaa ctaagatact tatattgtga ataataatgt
    74761 aactgtatat ttaaaataat acatcatgat ttaaaaaatt acaattgtac agatataatt
    74821 gagtttagat atttaaattt aacaacttat aatatttttt caattagtat aaagcctatt
    74881 aatttgtctt atttacaatg aatagtattt acttcttggc aaacaataat taaaaataaa
    74941 acttttatat gattaaactc taaagaaaaa gtttataaag aagataatat aattaagcag
    75001 aaaataatga aaaaaattta ttaaagtaga caacgtaagg agaattttat gaaagaaaaa
    75061 atttattaca atggaaatat catcacaatg gaagattcaa tatgtggaga tgctattctt
    75121 ataaaagaca aaataataaa aaagatagga acaaaagaag aagtatttgc tttgaaaaat
    75181 aaagatacag aaattataga tttacaaggt aagacattga tgccatcttt tatagattca
    75241 catagtcact tgatagcttt tgctactact ctaaagctag ttcctttaga agatgcaacc
    75301 agttttaaag acatagtaaa aaaaatacag gatttcaaag agtcgaataa tataaaaaaa
    75361 ggagactgga taattggatt ttcatatgat aataattttt tagaagaaaa taagcatcca
    75421 gataagagtg tactcgatag tgcatcttca gaaaatccaa tactaatttc acatgcttct
    75481 ggtcatatgg gagttgcaaa tacattgggg ttaaaacagc ttggtgttac caatgaaaca
    75541 cgtgacccag aaggtggaca tataggtaga gtagaaggca gtgaagaacc aaatggatat
    75601 ttagaagaaa atgcattttt taatgtagca tctaaaataa aacaaccatc atcaaatgag
    75661 atttttaatt caattgaaaa agcacagaac atatatctaa gctatggtat tacaacagca
    75721 caagaaggtt taatggaaga aaatcaattt aacattttaa aagcaatggc aaatcaaaat
    75781 aaattaaaaa tggatgttgt aggatatgta aatttgaaaa aaagtaagtc tgtagtagat
    75841 aataataggg agtttataaa aaaatatata aatagattta aaataggagg ttataagatt
    75901 ttcttagatg gttctccaca aggtaagaca gcatggttga gtagaccata tgaaaattca
    75961 gatgatggtt attgtggata tcctatatac aaagatgaag aagtagaaaa gtttatagat
    76021 atttcactaa aagaaaagat gcaactatta actcattgta atggagatgc agcagcagac
    76081 cagttgatag atgcgtttga gaaagtttta aacttaaaag agcaaagtag tgaaaataat
    76141 ataagaccag ttatgataca tgctcaaaca gtaagagcag accagattga tgatatgaaa
    76201 gtaataaata tgataccttc atactttgta gctcacacat attattgggg tgatattcat
    76261 atcaaaaacc ttggagaaga tagagcgttt aagattagcc cacttaaaac aactatagaa
    76321 aagggattaa tttacactct tcatcaggat acaccagtaa tagcacctaa tatgctggaa
    76381 acagtatggt gtgctgtcaa tagaattaca aaaaaaggta tacaaatagg agaaaatgaa
    76441 aagataagcc cattagatgc tttaaagggt gttactataa atgcagcata tcaatatttt
    76501 gaagaagata aaaaaggttc aattaaagaa gggaaattag ctaatttgat aatattagat
    76561 gaaaacccac ttacaatcga ccctatgaaa ataaaagata ttaaagtatt gcagactata
    76621 agagaaggag aagtattgta ttctttgaag tagatgaaag ttagatattt tataatctat
    76681 aaaaaatagt tttatataat aagttaggta gaattaaata agattacagt taaatcaaca
    76741 attatatttt tattaaattt taattattgt attgaagatt tataagtata attttattga
    76801 ttctaccttt ttaaataact gtagatttat taaagttatc tatgtactat attaaacaat
    76861 taagtagtta ttaattgcac ttattagttt attaaaaaac tatgtatatt actttgcagt
    76921 aagactttgg aactaaatct ataatagcaa atttaaattt attaaataga ttaccttata
    76981 acatttcata taaaatatat tgtgaatctg agaaaattac tatttttctt tgagtatttt
    77041 ttgtaagcag ttctaaaaga ttcaatttca tacctattac ttgaatcatt catcaaaata
    77101 attctaattt aaaaaataat tctatccaaa taatagatat ataggactat gttataatat
    77161 aaaaaaattt atataaaagt taataactat acaagattga taaagaaaaa gtcaaaatag
    77221 ataattgatt agcaaaatag atataattat aatgaagtta aatctagcaa tattctccta
    77281 aaattaaatt tcatttattt aattaaatat aatttgacaa tgggcaaaaa agtgagtaaa
    77341 atataaataa aataaaaata acaggttcgg ataaagaaaa aggtttctta acctcaagca
    77401 tgaagtatat tatctaagtt atttgagatt aagagataaa tccaatctta ggtactgagg
    77461 aggaaaaaat gcttgatata aaaagaataa gagaaaattt agattgtata aaaaaagcaa
    77521 tggaaagaag gggcgaaaaa gactttaacc ttgatgaagt agttaagtta gatgatgaaa
    77581 gaagaaagat tcttcaagaa gttgaagtta tgaaaaatga attaaataca gcatctaaaa
    77641 atataccaaa tcttataaaa gaaggtaaag atgtagaaaa tgaaaagatt aaattaaaag
    77701 agttatctga taaaattaag gtaatagacc aaaatcttaa agaagtagaa gataagatgg
    77761 aatacctatt aatgagaata ccaaatgtac cacatccaga agtaccacaa ggtgaaactg
    77821 atgaagataa tgttgaagta agaacttggg gaaagactac tacctttgat tttgaatcta
    77881 aggctcattg ggaaattgga acagaattag gtatacttga ttttgaaaca gctagtaaaa
    77941 taactggttc aagatttact ctttacaaag gattaggtgc tagattagag agagcattat
    78001 taaattttta cttagacacg aatacaaaag taaatggata tacagaagtt attccaccat
    78061 ttatggcaaa tagaaatagt tttttaggta caggacagtt acctaagttt gaagaagata
    78121 tgtttaaaat agaaggtatg gactatttta tgattccaac atcagaagtt cctttaacta
    78181 atatacatgc taatgaaata cttaaatttg aacaattacc gataaattat acagcttata
    78241 ctccatgttt taggtcagaa gctggttctg ctggaagaga tacaagaggt ttagtaagac
    78301 agcatcagtt taacaaagta gaaatggtta aaatagttgc accagaagaa tcttacaatg
    78361 agttagaaaa gcttactaac aatgcggaaa ctatgctaca attattgaat ctgccttata
    78421 gagtagtaaa gatatgtaca ggtgatttag gatttacagc ttcttttaaa tatgatgtag
    78481 aagtttggat gccaagttac aataggtatg ttgagatttc atcttgttca aactgcgaag
    78541 atttccaagc tagaagagca ggaataagat ttaaaagaga taaagattct aaagctgaat
    78601 atgtacacac attaaatggc tctgggttag ctattggaag aagtgttgca gctatattag
    78661 aaaattatca acaagaagat ggttctgtgg ttgttcctga agttttaaga ccatatatgg
    78721 gagtttctgt tattaaataa gagttaaatt atgtattttt aagcaataca ataatataga
    78781 ggtaataaaa aataattaat ataaaagtga tacttctaat atagaagtaa taaaaaaata
    78841 gttaatataa aagtgataca ataatataga agtaataaaa aaaaagttaa tataaaagtg
    78901 atacaataat atagaagtaa taaaaaatag ttaatgtaaa agtgatacaa taataataga
    78961 agtaataaaa aaaaataatt aatataaaaa tgtgtacaaa ctaatgaata ttgatatagt
    79021 aagctatcat atgaaagagt atgtacacat tttttttact aatttttcac aatatgaaca
    79081 taaataattt ataggaaagg aatcttttat gaaaattcaa aatactgagt ggggatatat
    79141 tgaatggaaa catacttatg atgaaaataa tccaaaacaa gctatgaata tatacattgc
    79201 agtaactatg cctggtaaga aacattttaa tcatgttcat tatggtcaag agcagatgat
    79261 atatatttta gagggagagg gtttgtatat tataaatgga gtttggaagc cattttatca
    79321 aggtatgatt ttttatatag aatctggtag cacacatgaa actataaata caggtgatag
    79381 agaaataaaa gaacttattg tttcaaataa tgtagatgat gtaggagaga gtgaagttat
    79441 agatattaat cctaataatt atttaaagaa gaccttgata aattatagtg aaagtacatt
    79501 aaatttgtat gcagcagtag aatcaattcg tggtcaattt atagacccgt ttaaaattcc
    79561 attaattata tatgatgatt catggaatat agttttaaaa aatccttatt ttccactttt
    79621 ttgttttgaa aaatgtaatc ctatgaaatt tcctcaaaat tgtgattgta tgaatcaaaa
    79681 aagtagcaat caatttgtat gtgaatatgg gataactata tataatatac caatactgta
    79741 caaaagcaat agcataggtg ttataagagg agggtatgta ctattatctg atttgaattt
    79801 agatacagag cataataatt tatatgatat tccagaggga gctgctagaa gtataaaacg
    79861 cctcctgaaa caaatatcta aaaatataat aaatttttgc tcttttaatg atataagaaa
    79921 ggatttacaa gaaaaagaga agactatagc aagaacatat cattatggag agcaacttga
    79981 aatgaattta aaagtagctc aagatatggt tactaattta agaataaatc atcacttttt
    80041 atttaataca ttaaattcaa tggcaagcat agcactagat gatggtagtt atgatttgta
    80101 tagtgcaata atagatttat caagaatgtt tagatataca atgaggtctg atttaagatt
    80161 tgtagaatta gaatctgaaa tattatacat taaaaattat ttgaatttac agaaattacg
    80221 ttatggagat gcacttaaag taaaatatct tattccagag aagttatata acctttctgt
    80281 gccttttaac tttattcaac ctattgtaga gaatgcattt acacatggat ttagagatat
    80341 tgacacagaa aagcgaattg aaataattgc aagattagat tctcagtatg ctattataga
    80401 gattcataat aatggaacta tcttagatgg aaataatata gacaaaataa aggcaggtat
    80461 tcgtagtaat aatggtcatg gtttgtcttt aatatataca aaattcacat ctgcttatgg
    80521 aaataatttt gatatggata taaagtcgag tgataatgaa ggaacttaca taatgattaa
    80581 aattcctatt gaaaattata aggagtatgt atagaacttg tgaaaaatta ataagtttta
    80641 taaatgttaa gaaatatatt agatgttttt atgttgtttt atatatctta cttttttata
    80701 ttattaagct aaaagggagg tattctcatg agaagagcac taataataga tgatgaagaa
    80761 gctgttctaa aaataataac acattttata gaaatgaaag atatgccaat aaaaattgtt
    80821 ggtaaagcaa catctggtga tgaagcagta gataaaatca ttggtttaga gccagacata
    80881 gtttttatag atattcaaat gccaatatac aacgggttag aagtaataga aaaaacatct
    80941 catttatcta aaaaaataaa ctttgtagta ataactgcat ttaactattt tgaatatgct
    81001 caaaaagctt tgagattaaa tgtaaaagat atactcctta aaccattgga tatgaaagaa
    81061 tttactaagt ctgtagaaaa aattattgga tatcaatata ccaataatga tttattaaat
    81121 gagatactgg aatatataaa tctaaactat agcaatgact taaagttaaa tgattgtgct
    81181 agattatttt taaccaatcc atctaatata tctaggattt ttaaaagtaa tttaaataca
    81241 acttttatat catatctaaa tcatataaga atagaaaaat ctattgagtt acttgaaaat
    81301 actacaaaaa gtataaatga gattgcagaa atagttggat ataatagcct aaataacttt
    81361 tataaaaact ttaagataga aaaaggaatg actccaaaag tttataaact gaacactaaa
    81421 aattgaaatt gataaataaa aagtcaatat agataattgt ttgagtgtgt ctgaataagt
    81481 atactttaat tatgataaaa attaaagcgc tttaaacata tttaataata ttaaacctta
    81541 taaaagctgt acctatttat ataaaaaaat atatataaat aaaaagaaaa agatatacaa
    81601 aataaaaaaa gtgaattaaa tactgtttca aaaagacaga attttcattt aatttactga
    81661 gagtttatat ttcttaaagg aaggtaactt tataatggag gtaatttaat atgtcagaca
    81721 aagtgaatat gaaaaatatt atctgtattg caggcgctta tctagcaaca gcaattggtt
    81781 ctgggtttgc tactggtcaa gaaattctac aattttttgc ctcacaaggg tatatgggtt
    81841 taattggagc attaatatca atggtattgt tttcatttct tggtgctgaa gttataacta
    81901 gaggtagaga attaaaactt aaagaaccaa caagaattta cactttttat tgtgggaaga
    81961 ttttaggaaa attttacgaa tggtttagtc caatattttt atttgggatt cttatagtaa
    82021 tgatttcagg tgcaggctca actttaactg aatactatgg tataaatcct tacttaggaa
    82081 gagtattgat ggctgttgct actttaatta cagtgtctat gggtttagaa aaattagtaa
    82141 gcatacttgg acgtattgga ccagtgatag cagtatttac aattgctgtt ggattaataa
    82201 gcttgtttaa gcattttgac ggtttatcta tggttggaga agctatgaaa aatattgaag
    82261 ttacaaaagc atcagaaagt ccaatcgttt ctggtgtaat atataataca ttaaatatta
    82321 ttgtaatgat tgttttttta acaggaatgg gagcttctat tgaaagtaaa aaggatgctt
    82381 tttggggagg tttattaggt ggaatagtgt ttatgactgc tggtatagtt atgtatttgg
    82441 ctatgatttc agatatagga aatttgtata tgaaagaaat accatcactt tatttagcag
    82501 ataatatatc tccgattgta ggtgtatgtt tttcagttgc attaatatta ggtatctata
    82561 caacagctgt tccactttta tggtctgtaa ccaatagaat tgttgaagat gaacatccta
    82621 aatttaaatt ggtaacaaca gtaatagcta ttttggcttg tataggaggt tttttaccgt
    82681 ttggtaaatt agtaaacatt ttatatccat atacaggtta tatggggctt ttaattttag
    82741 tctgtatggt gtataaagca attacatgta gaaaaaaatc aacacaaagt caggaataga
    82801 gccacttatt aatagttttt atttaaaaaa attttttata taatccgaat ttaaaaagtc
    82861 aaaatagtta aataaattgc aaaacatgat aatatattta attaaaataa tatagtaaaa
    82921 tataaatata aactaaaatt aaatttataa aaaatatctt tataaagatt attaacttat
    82981 ataatttgta gttaaattat aaaaaataaa aaaataaaat tttggagagg tgttagtatg
    83041 catgaactta ttttaatctc agaaaagtat aaagaagata ttttagattt ttttacagat
    83101 attcatatgc accccgaatt aagttttaaa gaatttagga ctacaaaagc tataaaagat
    83161 ttattagtga gtttagacat agaaatatta gatttaggaa tggaaacagg agttgttgga
    83221 ttattaaaag ggaagtatga tggtcccaca gtagcactaa gaggagatat tgatgcgttg
    83281 ccaatatatg aagaggttga tattaagtat aaatccagat atgatggtat aatgcatgca
    83341 tgtgggcatg atatacacac gtcttgcctt gtaggatgtg catatgtatt gtctcatatt
    83401 agagatagtc ttcatggaaa tgtaaagttt atatttcaac cagccgaaga agtcaataaa
    83461 ggtgcgaaga tgttagtgga acgaggagta atggaaaatc caaaagttga tgctatattt
    83521 ggacttcata atcatccaga tataccttgt ggaaaaatag gtgttaagtt aggtgggtta
    83581 atggcagcag tagacactat taagatagaa gtaaatggat ttggaggtca cggaggtata
    83641 ccaaacagaa caatagaccc tatagtagca tcaagtgcaa ttataatggg tattcaaacc
    83701 atagtaagca gaaacataag tccattagaa tcagctgtta tatcaatagg tactataaat
    83761 ggagggactg caaataatgt aatttcagaa aaggtagata tgacaggcac atgtagaagc
    83821 tttagtaatg aagtacgaaa gaaaatatca gaaaatttag aaaatatagt ttgtgagata
    83881 gctcgtggat atcaagcaac tgcaaagcta gattatttat ttgatttacc agctgttata
    83941 aatagtaaag agatgtacgc aatagcttgt aagtctgtgt gtgatttgta ttcagaagat
    84001 gctatagttg atccaatacc ttctacagga ggagaagatt tttctatatt catggaaaaa
    84061 gccccaggat ttttttactg gttaggggta ggcaacaaag aacaagattg tatatatcag
    84121 tggcataatc ctaaatttaa agctgataaa aattctatat tggtaggtac aaatgtacta
    84181 tgtcagtctg ttataaatta tatggataaa ttaaaaaata aaatttaaga tagagcattc
    84241 tggagataaa gtttatgagg gggtattagt ttgaggaaaa ttaattcaca ggaaaaaaac
    84301 aaagatagtg gattattgat gagggcacta aatgttgtag agagagcagg aaataaactt
    84361 ccagacccag taaccatatt tttattacta tgtataattg ttgtaatatt gtcagcagtt
    84421 atatctaatt taggagtaga agaaatacat ccttctacaa aagaagttgt aaaggtagta
    84481 aatctactag agaaagagca gattcaatca tatttaggta gcatagttac aaactttcag
    84541 tcatttgctc ctttaggatt agtactggtt acaatgcttg gagcaggtgt tgctgagaaa
    84601 tctggattta tggaagtgtt aatgaaaaag ggtataagta aagttccaca aaaacttgta
    84661 actgtagcaa tcgtatttgc aggtatgttg tcacatacag cagcagatgt aggatttata
    84721 atattaccac cacttgcagc acttgtgttt ttaggaattg gaagacatcc tcttgtaggt
    84781 atgtttgcag cttttgcagg tgttgcaggg ggatttgcag caaatgttat gcttagtact
    84841 acagatgtat tgttagctgg atttacaata ccagcagctc aaatgatgga cccatcttac
    84901 caaggcaatc cagcaatgaa tctttatttt gcttttatat cagcgatagt tttaactttt
    84961 gcaggagcat ttgtaactga aaaatttata gctcctcgtt ttacaaaata taatgattca
    85021 acaaatgata aggatataca ggaattgagt gaacttgaaa ataagggtat aaaatacgct
    85081 ttattatcat tgttagttgt agtagtagtg atagttgcct tatgtatagg tgacaatgca
    85141 tttatgaaag atccagagac tggttctata ctatctagta atgcaccttt aatgaaaggt
    85201 atagttccta taatcactat tatattttta actccaggat tagtgtatgg aaaagtaagt
    85261 aagaagataa aaagtgacaa agatttagta tctatgatgg gtagtagtat gagtgatatg
    85321 ggtggatata tagtcctagc atttatagca tcccagttta ttaatttatt taatcttagt
    85381 aacttaggaa caattttatc aataacagga gcaaaattac tagcagagtc ggggatacct
    85441 agctatggat tgataatagg atttatattg ctatctggat ttatcaattt atttgtagga
    85501 agtgcttctg caaaatgggc gattttagca cctatatttg ttcccatgtt tatgctacta
    85561 gactttaatc cagcattaac tcaaatagct tatcgtattg gagatgcttc aacaaatcca
    85621 ataagtccac tttttccgta ttttccagtt atattggcct ttgccagaag atatgataaa
    85681 gatataggta taggtactgt catatcgaat atgattccat actcagtggt atttacatta
    85741 atagaaataa taatattgtt actattcatg ggtattggca taccattagg acctggtgga
    85801 ggaatatctt acgttttata gaccgttata ataaatttat caatgaagat taaactaata
    85861 aaatatattc tttaattaag aggaggatta ttatgttaaa aacaacaaaa atttcagacc
    85921 cagagttata caagattgta gctgatgagt tggttagaca agaacacaat attgagatga
    85981 tagcttctga aagtacagca ccaacagaag tacttgaatt aagtggatgt gtatttacaa
    86041 ataaaacaga agaaggctat ccaggggctc gttttcaagc aggttctgaa gaagcagata
    86101 aacttgaaac cctagcaata aaacgtgcaa aagaagtatt tggagcagaa catgtaaacg
    86161 tacaaccgta ttcaggttct acagctaact attgtgtata ttcatcaata ttaaaaccaa
    86221 atgacactgt tttaagtatg cgtcttgacc aaggtggaca cttgacacat ggtagcgcag
    86281 ttaatttttt acatgacatt tataaatatg aattttatgg ggtagaccca aatactggac
    86341 gtatagatta tgatgctctt gaagcaaagg caaaagaatg tagaccaaaa cttataattg
    86401 caggggcaag ttcatatcca agattaatag attatgaaag aatatcaaag gttgcaaaag
    86461 aagtaggagc ttactttatg gtagatatgg cacatgttgc aggattagtc gcagcgaaag
    86521 taatacctag tcctgtacct tatgcagatt ttgtttcttc atctacgaca aagactttct
    86581 gtggaccaag aagtggtatt gtactttgta aagcagaaca tgcaaagaaa ctcgataaag
    86641 gtgtttttcc aggaacatta ggttctatac atcttaatac agttgcagca aaagcctttt
    86701 cactattata tttaagtaca gataaattta aaaagataat ggagcaagtt gtagtaaatg
    86761 ctcagactct agcttctgaa ctgatttcac atggttttag tattgtaagt ggaggtactg
    86821 ataatcatat agtaatggtt gacttaagaa gtaagaatct tacaggaaaa caatttgaaa
    86881 aagctcttga atatgtagga ataacagtta ataaaaatgt tatacctgac gacccacaat
    86941 caccatttgt aactagtggt gttcgtatag gtcttacatc aatatctcaa agaggtctga
    87001 aagaaaaaga agttatacag atagcaggga taatgaataa ggtagcagaa aatattgata
    87061 ataaagaagt attagatgaa tgtaaagcag aggcacaaga acttatatct aagtttccat
    87121 tatatccaga agggtatttt gaagattaaa tattttgatt tgtatagctc acaatttata
    87181 aagcctgtaa cataaaattt aataatatat aaccactata aggtgttgat taatcaacac
    87241 cttatttttt ttgaaaagta atatacaagc tatcataagc atataattcc ttatagataa
    87301 ttaacaaggg ggataaagtt atgaggtatt ataataaacc taccaaagaa gtattaaaat
    87361 acttaaaaac aaatccagaa attggacttg atgataatga ggtagaagaa aggaagctta
    87421 gatatggatt aaatgaattt actataaaag aaggtagaac attttgggac gagttgggag
    87481 aaagtttgac agaacctatg atattaattc tcataggagc agcagtaata agttcttttg
    87541 tgggagaatt acatgacgca ttaggtattt taggggctat ttttattgga atttctatag
    87601 gcataataac tgaaggaaaa tctaaaaaag cagctcatgc cctgtcaaaa ttaacagaaa
    87661 atatagaagt aaaggtgctt agaaatggga agataattaa aatatcaaaa aatgatttag
    87721 taccaggaga tattgtatat atagaaactg gggatatgat accagcagat ggaagactta
    87781 tacagtctat aaatttgaaa cttagagaag atatgctaac aggagaatct gatgatgtag
    87841 ctaagaatgc tgatgctgta ttagatatgg aagtagttta ttctaaaaca gaaataatcg
    87901 aacaggatgc aatacctgca aagcaagtca atatggtatt tggagggact cttgtagcat
    87961 atggtagggg cataatggtt gtcactcata ctggtgataa gacagagatg ggtaagatag
    88021 cacagaattt atcaaatgaa gaccagcaaa ctccacttca aattaaatta gggaagttgg
    88081 gtgctaaaat agcaggaata tcaggcataa tagctacttt attgtgtatg tttatgatta
    88141 tacagatgca gagaaaaggt atgttaattt tagatacaag cagtgtatta tctttcttac
    88201 aatcattaga acctgctaaa aatgcatata tggtttgtat tgcattaata gttgcaactg
    88261 ttccagaagg tttgccaact atgataaata ttaccttagc tataacaatg caaaagatgg
    88321 caaagataaa tgcattagta acaaagaaag aagcctgtga aactataggt tctgtttctg
    88381 taatatgttc cgacaaaaca gggactttaa cacaaaacaa aatgatggta gaggtagcat
    88441 atgttgatgg taaatatata agtggaggag agtatcaaag taatagctat tttgaacaaa
    88501 actgtatagt aaattcaact gcagatatag aaaaagaaga taattcattt aaatatatag
    88561 gaagcgcaac agagtgtgca ttacttttat atcataatga taagaactat aatgaaatga
    88621 gaaaacaaac gtatttgata tcacaaatac catttagttc agaagaaaag aagatgtcaa
    88681 cattaattcg tcaagaggat tcagatatat tactttcaaa aggtgctcca gaagtattat
    88741 taaaaaaatg ttcttatgta caacaaggaa aaaatattgt tccaataact ccaaaagtag
    88801 aaaaaagtat tttagatgag attaagaagt tacaaattaa atctatgaga acattaggat
    88861 ttgcttataa aaaaatgagt aattctaaaa cagaagttgc aatgacttca gaaggtgaat
    88921 tgaatttaat aggaaattca agaagttata tgaaggaaga taatttagtt tttagtggat
    88981 ttgtaggaat agtggaccca ttgagagaag gggtcaaaga ttccattgat aaagcattta
    89041 atgcaggagt agatgtaaaa atgcttacag gagataatat aaatacagca acagctattg
    89101 gaaatgaatt aggactatta aatgatggga aaaaggcagt tgaagcaaca tatatagatg
    89161 tattgacaga taaagaattg agagaagaaa tcaaaggaat atctattgtt gcaagaagta
    89221 aaccagatac aaaaatgaga atagtttcag cacttcaaaa aagtggcgaa gttgtagctg
    89281 taacaggtga tggtataaat gatgccccag cacttagtca agcagatgtt ggaattgcaa
    89341 tgggtatttc aggaacagaa gtatctaaaa atgcagcaga tataatattg actgatgata
    89401 gctttagtac tatagtagag ggaataaaat ggggaagagg tatatatgag aactttcaaa
    89461 gatttataca gtttcagctt actgtaaata tagtagcatt tataattgct ataatatctc
    89521 aacttactgg taaggatatg ccatttacta caatacaatt attatgggta aatataataa
    89581 tggatggtcc tccagcccta gcattaggat tagaacctgt tagagattat gtattgaaaa
    89641 gaaagccaat aaatagacat tctggaataa tagctaggtc tatgtttgta aatattatta
    89701 taaatgctat tcttataatt acaattgtat ttactcaatc agcttttaat atattgggag
    89761 ctacatcaga agaacaaggt actgttatat tttctttatt tgcattcagt gcccttttta
    89821 atgcattaaa ttgtagagag tttggtttaa atagtacaat accaaatttc tttaaaaata
    89881 aactagcatt gcaaataata gtagttacag ggataattca aataatattt acacaagtgt
    89941 tccagagttt ctttaattct gtttctttgg actttgatat gtggataaag ataatactat
    90001 ttgcatccac tatcctattg tcaaatgaat ttgtaaagct aattcttaga acaatgaaaa
    90061 atagtagaac tatgaacttt aatagtaaaa attaattctt atgaaaccgt aaagtactat
    90121 atattgtaac tttgcggttt ttgtttgttt aatgttgttt tatattacca ttttcatatt
    90181 taatttttta ttaatctgaa cacaatcttc cattgtaatt gcttcatctg tgtcaacaca
    90241 ttcaaagtca atatctaatt tttgtaatat tttgtatgcc tttttttgca aaggagtatc
    90301 aaatttaata ggtgattttg tgtaaatatc actgataaaa aacatgattt atttcattcc
    90361 tttccattta aaatcttata gttatagtgt atcataaggt tataaaatat agataaatat
    90421 agtataaatt taaaatatgt acagacaaaa caaaaaaatc atattctaag taatacttgg
    90481 gaaaaatgat attatcataa taaataatct ttgtaaaaac ttatatagaa tctattaaac
    90541 agacactaag ccataaaaac tttactaaat ataaaattcg tatctaaata gatatataga
    90601 ataatatttt actgaagtag agtgattttt aagaatttta tatataaatt atgttatcat
    90661 aaataaagag atagattata aaatttgtta ataaaataaa gggcagggag gtaagtttca
    90721 tgttttccaa aatcctagtc aaaacattta ttagagatag cgaaaacgtt caaaatacag
    90781 atgttagaaa taagtatggt tatgtagctg gtgtagtagg tatattatcc aatttacttt
    90841 tatttgtgat aaaggtattc ataggaatgc tcacatctag tatagctata atggctgatg
    90901 catttaataa tctttctgat atggcatctt cagcaataac tatgataggt tttaaattag
    90961 caagtaagcc agctgataaa gaacaccctt ttggtcatgg aagaatagag tatttatcag
    91021 cattaatagt agcatttatg gtgatgttgg ttggacttca atttgtaaag tcatctatag
    91081 aaaggatagt aaatccaatt cctgtaaaat ttgaagtaat accacttata cttttaattg
    91141 catctataat gattaaaatc tggttgagtc gttttaataa atttatggga aataaaattg
    91201 attcttcagc cttaaaagca gtttcacttg atgctttagg agatgtattt acttcaagtt
    91261 gtgtagttat atcatttatt gtagctagat ttactaattt tcccatagat ggatatgttg
    91321 gtatcgtagt atcattagtg atactttatg ctggtttctc tcttgtaaaa gatactataa
    91381 atcctctttt aggggaagca ccggatgaag aaatggtaaa ttctattata gagctattgt
    91441 tatcttataa atatataata ggtacacatg atttaattat tcataactat ggagttggta
    91501 gatgtattgc atctatacat gcagaaattc catccaacat agatataatg gaaatacatg
    91561 aaattataga tactgcagag agagaaatat ctgaaaaatt agatatatat ctagtaattc
    91621 acatggaccc aatatgtctt gaagataaag aagttatgtc agccaaaaaa gaacttgaag
    91681 aaatacttaa gaaaaatagt cttgtaaaat ctatgcatga ttttagaata gttggaaaag
    91741 gaagcaagaa gaatttaata tttgatatag tagttaatcc ttccgaattt tccaaaaaca
    91801 tgtcagaaga tgacttaaaa gaagatataa caaaattagt taaggagata aatcctgaat
    91861 ataattgtgt aattgttgta gacaaggatt ttatttaatt attaattaat ctcatcataa
    91921 ggtaaaaaat gtaaaaagga tagacaatag tatagaggca taatataata gaagtatata
    91981 attgtatttt taatataaat aaagcaattt taattgtttt tatgaaatat tatagagatg
    92041 ttgaagtata ttctattatt gggcacctta tggatatact gagtcagtgg tgcaaccggc
    92101 tatgaatata aatttattta ttttcatagc tttttttgta taatttttta gtaaaaatta
    92161 ctttatatac gatattaatg gaagattaga ttataaatta taggtaacct aaaggggtga
    92221 gatttacatg aagaaaggaa atagaaaggc attattaatt agtttaatta tgattttaag
    92281 tatggtggtg tctacaatat atccaactgt atcttatgct tcggaattag gagagaatag
    92341 tcagattcaa agtggttcaa ctaattcatc aactggagag gagaaggaaa gcgacaataa
    92401 aaagccagaa cagactccag agaaagataa ggcaacagat aataaaaaac cagaacagac
    92461 cccagaggaa gaaaaaccaa cagataataa aaaaccagaa cagaccccag aagaagataa
    92521 gtcaacagat aataaaaagc cagagcaaac tccagaagga gaaaagccaa tagataataa
    92581 aaagccagag cagataccag aagaagataa gtcaacagat aataaaaagt cagaacaagc
    92641 tttagaagat gaaaaaccac tagataataa aaatacagaa aaaactccag aggaagataa
    92701 tctattagaa gatgaaaatt tattgaaagt tttagaagaa gaacttaatg aagaaaatga
    92761 agactatgga tttgttgtaa aaattaataa caatacaata gaaacagaat caatgaaaaa
    92821 aatatcattt aatttaactt atactccaac atcaaaagga atacaagcag gagattcaat
    92881 aacttttaag gtgccagatg tattcaataa agttaattta gattatacaa gtgaatgctt
    92941 tgataaaaca gaaagtaatg gagagtatac acttacattt agagaattac ctaatggcca
    93001 aagtgtaatg caaggtaaaa taggtttgga agcatatgtt aaaaaggttg atgaagatac
    93061 taatgcaaaa atacatattg aaactactgg aaaaatagaa agtggaagtg gagatataga
    93121 tgtagaaata aaacctggag ataaaacgga tgttccagat gctaaaggaa cacttaaaaa
    93181 gcttgttgaa ggaaaaaaat caactactgt atttatgcca gttaaaaata aagatataaa
    93241 ttacagtata caagtaaatg aaaagcagga agagttaaaa gatattattt tgtatgatga
    93301 gcttcctgaa ggattgacat tgataaatgg ttctgtaagt gtagtaacaa gtgatggaaa
    93361 agaagttagt gattttaata ttgaacagag taaaaattct atttcagtta attttggaaa
    93421 tatagataaa tcgtatactg ttaagtataa ggctagaatc agtgacaaaa atgcaaaaca
    93481 tggtaataaa tataagaatg tagctaggat tgaatctgat ggtaagaaga tacaagaaga
    93541 tgatgctact gtaagtatat ttgatagagg agatgattat cttcttacta aaggacattc
    93601 aggagcaaca aatattactc aagttggtca agtaataaac tatcagattt caataaatga
    93661 tgataaatca ccaataagta atgttgttat aacagataat ataccagaag gcatgagatt
    93721 aactacttca ggagaagctg ggcatgattt tagagttgta gaaattccaa tgaatgggag
    93781 ctggactcct tggagtaaag aaaaaattgc caataatatt tcatataaag tagaagaaaa
    93841 aagaaatgaa agtgggcaag tagataaagt tataactgga tttacaatta atctcagtaa
    93901 agaagaagtg gaatcaaagt tttttatagc ttatacatta aaggtaatta gtattgaaga
    93961 tagctatata aatagagctg ttcttgatgc aaataatagt gaaattgata aaaatgatga
    94021 gataaacttt aagaaaaatt ctggattaat aagcgcaaaa aaagaagttg ataaaaaagt
    94081 tttaaacagt agtgataacc agattgttaa atacaaaatc aatatgtcaa cttatggagt
    94141 ttatgatgca ggacaagtaa atcttttaga tgaagtaaac tcagttctag aaatatctaa
    94201 tataaaatat tctgataatc ttgaacttaa aaaagaagct ggagatggaa aaaatacaat
    94261 aagattagta aataaatacg aatttaaaca gataaaagaa ggggaacctg tgcaaagttg
    94321 ggttacattt gatgcaaact tcacaaatgt aaaagttggg gagactatac gaaatgtggc
    94381 tcagattaat ggttcaagtc ctccaggagt agagactact aagcaaggtt atgcttttga
    94441 agctaaaaaa gtggatgctt tagataaaaa tgtactttca ggtgctaagt tcaatttaga
    94501 agatgcattt ggaaatatag tagttaagga tttagttagt gatgaagatg gtataattca
    94561 atctagtgta aaaaacccag gaacatatta tttagtggag ataatggctc cacgtggata
    94621 tgaaaaactg aaggataaag ttaaggttga aattggtaat gaagatattg gtaagatagt
    94681 agatattgga aatatagaaa atctaaaaca agaaaatcca ccagtaaatc caccaatacc
    94741 tccagataca gatgaaccaa tggtaaatcc accagtacca ccaagcacag ataaaccaag
    94801 gaaaccatca agttcatctg atacagagga tactatagtt ataaatccac cagtaccacc
    94861 atcagaagat ataataaatc cgccaatacc agaggtattg aatccgccag taccaccatc
    94921 agaagagatg atagaaactc ctgttaaaca gattattcca ataccagaag tagtaaagcc
    94981 atcagtgtca gaagaaaaaa ataataaagt taaagatgat actttggtaa atccaccagt
    95041 accaccaaaa acaggggata gtactacaat tattggagaa atacttttgg ttataggagc
    95101 tattgtagga cttatcgtat taagaagaaa taaaaataca aattagaccc taacattata
    95161 aaaaatataa gttatattaa aaaatatctt ctaaaacaat atttaataat gaaaatattg
    95221 ttagaagata tttttttttg aagatttatg taaaaaaata ataacttttt agaaaaaagt
    95281 tccaaaggga tatagacaat taaaaagata taagctataa tatagatata aaattaaatg
    95341 aggcaaaact agggaaacct agtcacgcaa agctataggg gctaaagttt agtaaaccat
    95401 gccagccagt tgccgaaaag agtaaaaatt tctttttgta tatacaaaga tactcttggg
    95461 tatctttttt attttgaaat ttattactcc cggcctaact caaaggaggg aataatatga
    95521 gaccaagtaa aaaattatta atagctataa tatcaatatt cttaataagt tcagttccag
    95581 taagtgcaca tgcagatagt actactatac aacaaaataa agacacactt agtcaaatag
    95641 tagtttttcc aactggaaat tacgataaaa acgaagctaa tgctatggta aatagattag
    95701 ctaatataga tggaaagtat ttaaatgcat taaagcaaaa taacttaaaa ataaaattat
    95761 taagtggaaa gttaacagat gaaaaagaat atgcttattt aaaaggtgta gttcctaagg
    95821 gatgggaagg tactggaaaa acttgggatg atgttccagg tttaggtgga agtacagtag
    95881 ctcttagaat aggatttagt aacaaaggta aagggcatga ttcaataaat ttagaattac
    95941 atgaaacagc acatgcaata gaccatatag tattaaatga tatatctaaa tcagcacaat
    96001 tcaaacaaat atttgctaaa gaaggtcgtt ctttaggtaa tgtaaactac ttaggtgtat
    96061 atccagaaga attttttgca gaatcatttg catattacta tttaaatcaa gatacaaata
    96121 gtaagttaaa atcagcttgt ccacaaactt atagcttttt gcaaaattta gctaaataga
    96181 gttttaataa atttaaaata aatataaata aagagatgct attataatgg catctctttt
    96241 atattgcgtt taaatctaat aaattttgtc ttatgtataa ctatgataga ttatcaatta
    96301 ctactcctta tacaaggctt caacgtgttt attatgcatt tgagtaatta tcgtaggtat
    96361 aatagaaatt attgaaccaa ttactatcaa taaaattcct acaaccatgt ttatagggat
    96421 aatttcttta agtattaata atgctagtat tggagatatt actggtttaa agaagaatac
    96481 taaagatgta agactagtag atgtagcttc cattgccata aagtaaagcg cataaccaac
    96541 acctgtaaca aatacgaata cataaatcat aatgggcata ttgtgtaagg tatatccact
    96601 aaaaataggg atatttgcaa atacatgaag cttattttta tttaatatat ctgcgataaa
    96661 attaatttta gtgagtaaaa ccaatatcaa catttccaaa ctaccaaata taaagctaaa
    96721 gcaggttaca actattccac caaattttaa ggtttttctt ttaccaaata cagtatacat
    96781 tgaaaaaata atagcagaag ataatgttaa gaatattcca ctaagagtta gttttgtatg
    96841 caatggattt attataacta taattccaag aacttctaat ataagtgaaa ttacattgtg
    96901 cctatatatt ttttccttca aaattaagta agctaaaagc attacaaaga ctggattaca
    96961 actgaacaaa acagcaacta cagatgcctt tgtgtttaga acagcaagtt gatacaatga
    97021 catacttact actacacaca taaaacctaa aaatgcaaag tattttaagt ctgattttgt
    97081 aatagaaaga ctaagggctc ttaatctttt tacagcaaaa ggtagtaaga ctaaaccgcc
    97141 aacaaaaaat cttgataaag ttatttgtaa gggattaaag tcattagtga cagtttttag
    97201 actaatttcc attgaactaa aaaataaggt agtcagtatt atataaacat aacctttttt
    97261 caagtcaaac acctccttgt aatttatatt agtactatag ataagaatat tcaagcatat
    97321 tggaataata tggtatgtat aaaatatagt acataaaatt ataaactacc ttaatataga
    97381 atgtaagtat tctatactaa ggtagttaat tatttgaatt actttgattt agttatttta
    97441 aattatataa tttggctaat ttttcaaatg ctggtaaaga acttttaact ttatcataag
    97501 atacacaata tgatactcta aaatgacctg gacaaccaaa agaagaacct ggtactaata
    97561 ataaattaaa ttgttttgca tcattgcaga attttttatc atcttcaatt ggagcttttg
    97621 ggaacaaata gaatgtacca ttaggtttaa cacaagaata tcccatatcg attaaactat
    97681 tatatagaag gtcaaaattc tttttataaa tatttacatc aacttctgca tctaaacttc
    97741 ttgcaataac cctttgaaaa agagaaggag catttacaaa tccaagtatt ctatttgcaa
    97801 catttaatga agacataaca tcatcaaaat catccatttg cccattagca acaatatatc
    97861 ctatacgttc accaggtaga gataatgatt tactataaga gtatcctata aatgaatttc
    97921 tatagtattt tagtacacaa ggaactttgg caccatcata aattatttct ctatatggct
    97981 catcagaaat taggtatatg cttgtattaa attctttttg ttttgaatcc aataattctc
    98041 caagattttt taataattct tcagaatata tgacaccagt aggattattt ggagtgttta
    98101 ttattaaagc tcttgttttt ggagtaatag cattttttag agcatctaaa tctggctcaa
    98161 aagtctctat atttgtagga acttctatta attttccatc atagttttct gtataatttt
    98221 tatactcacc aaaatacggt gcaaaagcaa taacttcatc accaggattt aaaagagttt
    98281 ttaaaataat atttagacca ccagcagcac cacaagtcat aattaaattt tctcttgtaa
    98341 gatttaatcc atctttttta tttatgtgtt cagcaatagc atctcttaca tcctcatatc
    98401 ctgagttgtt catatatcca tgaactaaat ttggagattc ttcatttaaa atatcattta
    98461 taactgcttt aatagtctct ggaggttcaa cacttggatt tcctatacta aaatcaaaaa
    98521 cattttcctc accataaata tcagaaagtt tctttccttc ttcaaacata gctcttataa
    98581 cagaactatt tgcaactaaa gtttgcattt tattagatat catatgtaac actccttttt
    98641 atagatttat attgcttatg tatatattac catattttta ctgaatttag acaattttcg
    98701 aaaaattact tgtttgaaaa tataaacttt tatataaaat atatttatgt acagtgcata
    98761 ttaaaaattc caatttctaa ttttatcatg attattttat ataatagttt tttaaagaat
    98821 taataaaaca tagatttaga gaataaaata ttcttgacta tattaattgt ttaatataat
    98881 atagttgata tagtcaaaca tattataatt atagaaggga aatttaagat ggattttaaa
    98941 aatttacagt atgaaagttt gtcatatatt atttgtaact tgcaaaaaaa ctttaaactt
    99001 tattgtgaaa aatgtttaaa accatataaa cttacgaatg gtctatattt ctatttaatt
    99061 tatattaata aaaataggaa ttgttcttta aatgatgttt ctacagaatt tgaagttgat
    99121 aaagctcata caacaagaac tatatctagg ttagaacaag atggatacat agaaaaaatc
    99181 caaaacccta atgatagtag agcttttcag ttgagagtaa cagataaggg tgaggaagta
    99241 ttaggggata taaaaaacat attttcaaag tgggataatc acataaaaaa agagttctcg
    99301 gatacagaat ataaagaact ggtaaagaat ttacatgtgg taaaggatat aaaaacagct
    99361 gtggaggaag aataggatgt attgtaattt attaaaacca attaaaattg gaaatttgga
    99421 attaaaaaat agagtatctt ttgcacctac aagcatgggt cttaaattgg aagaaaaaat
    99481 taaaaagttt tctgatattg ctaagtcagg agtagctctg attactctag gagatgtatc
    99541 tattagacct agttttcata aggtagctat aagcctatcg gatgaagatg gagtcatgaa
    99601 atacaagaaa attgtagatg aaatacacaa ttctggtgca aaggtatcag cacaactatt
    99661 ttgttcagat tatgatgtta atttaattaa agatactatg aagatgggaa ttacttcaca
    99721 tgatgagata aaaaaaataa tgaatgacgg agtaaaagat tacataacaa atatgaccaa
    99781 agaagaaatt aaaaatatta taaatttatt taaagtaaca gcattgaatg caaaaaaagc
    99841 aggttttgac atgattcaaa ttcatggtga taggcttgta ggaagttttt catcaagtat
    99901 atttaataat agaaatgatg aatatggtgg aacgtgtgat aatagaagta gatttgcaag
    99961 cgaaataatt agtagtatcc gagatgaagt taaggacatt ccaatagact ataaatttgc
   100021 aataagacaa gaaaatcctc attatggaaa tgcaggagtt ttactttcgg aagttgagta
   100081 ttttgttaaa aaatttgaat ccctaggtgt aaacagtttt catgtaacac ttgcaaatca
   100141 ttcaaaatta gaagatacta taccaaccaa taatcatcct tactttaaag atgaaggctg
   100201 ttttttatat ttagctgatg aggtaaagaa acacacaaat cttccagtat gtggggttgg
   100261 aaaattgtct agcccagatt ttatagaaag tattatttca aataatagag tagatatggt
   100321 ttctatgtca agacaattac tagcagatag taattggtta cagaaagtaa aagatggaag
   100381 agtagatgag attaaaaagt gctgttattg taataagaag tgtgcagatg ctttacaaac
   100441 acgctctcag tttggatgta tactagatta gaatatcctt ataaaaataa ataatttgtt
   100501 aaggttaata tatttttggt gatttagata agtatttaga taaagaggag gagacatcat
   100561 gaaaagttta gttttatatt caagtttaac tggaaatact aaaaagattg cttatactat
   100621 atatgatgaa attcaagaag aaaaagacat taaagatgta aatgaattag ttgattatag
   100681 tattgactat gaaaattatg atatagtatt cttaggctat tgggtggaca agggaatttg
   100741 tgataaaaat tcaaaacaag tgcttgaaaa tattcacaat aaaaagatag cactatttgg
   100801 aacaatggga gcaagtaaaa aaggaagtta tggagctagt ataatagaaa agatagaatc
   100861 aattatccca aaagataatg aaatattagg ttcattcata tgtcaaggta agatagcaga
   100921 aggattgaaa gcaaaatata aagagatgct aaaactttct cctgacaacg aacatattcg
   100981 ccaacaatta aataaccatg aggaatctca aagtcatcca gatgaacaag aaatatatga
   101041 agccagtatg tttgcaaaaa atatgatgat taaagctagt attgtgtagt agttaaacaa
   101101 taagttcata taagatatag aataaataat ttagtaaaaa agtatagcaa ataatttgct
   101161 atgctttttt tatgaaatca aaaaaataat aaaaatactt gactgtaaac cttgtttata
   101221 cattatttta tagaaaataa gatagtttta aatataaaaa aagatatatt attgaaagga
   101281 gatattattg tatgaaaact tataaaagat aattagtttg attttaagat atactaaata
   101341 tacaatttta tagagtgaaa atatttaaga ctatattata gttataaatt aatagaatag
   101401 agaggtagtg tttaaattgc aataacagta tttccaaagt tgccacctca aattcctatc
   101461 caatggaata atggtgtagc taattatgta gataaaaaat ttatttatgc ctaccctgtc
   101521 atttgtgttg tattcagaat acttttacgt ccatttatat ggagatggtt acaaatacat
   101581 gctttttata gtgatactat tgcagattat ttaacgaatt ttatgtgttt tgtagcgttg
   101641 tctatagaaa tcttctctat actttttatt tacaatattg ccagacatgt tacaataatt
   101701 atttttatag atatacttgt atttattgct ttactgataa taggtatgta taaattattt
   101761 aaaaaataca attaattttt aaaaattaag taataagtga tagtgtaaaa agtagccact
   101821 gcaaattatg gattgtagtg gctattttat tatttgtata tgaaattatt ttgtttttct
   101881 aataagttac gatatattat ggtttatttc actgataaaa ggtttaggta ttttaaagta
   101941 aaaagttgta tattctaata aaatttaaac attttgattc tttaaaatta gagaaaatac
   102001 attgctttta ttaaaaaatt aaatattaag aatttaattt ctgcatctta tttagaaaag
   102061 ataagaaatc aactttatat attttttttg gccttcctct ttgattatcg agttttgtat
   102121 ttacaatagt tgcaattcct gctttatata aaatactcaa tattctatta gcacttctaa
   102181 gagttatgtt catatagtct gctaatattt ctgctgacac attatttgaa tttctatcat
   102241 taatcataca catgatttta gatacatttg tattagatag aggtataaaa gaagcaactt
   102301 tattggctat tgagctatct tcaatattat tagaattttt atttgaatat aaaggaccta
   102361 ttgtatcatt agtatcattt actataaaag tacagtttcc attcaaagaa gcagatttac
   102421 cattagcttg acgagcattt tgctctgcat gaatatttgt atttccaatg ccccaaccta
   102481 tatttaagct atatttaatt tcttttaaat cttctgaaat aaaaaaatct gtatagttat
   102541 tggtcatatt gtttaacatt tctttagtag tgtgtatctc tattttcata tcattttttt
   102601 tgacctgaac tccatagaat ccatgtcttg atagagaatt taatatagtg ttatatattt
   102661 gattttgtat ctcatcattt ttaaatatca aatcttcatt tatgtactct gaactattta
   102721 ctgtaactat acaagttgca gatttatttt tgtctaagtt ttgtaatgtt atttcattca
   102781 ccagagattt aaatgtattc aggattgatt ctgtagatgg aaccatgtaa atacaatcat
   102841 atccaagctt attaagttca caactaatga tgtaatttct agtaaaagaa aggttaatct
   102901 tattatctcg caataagtct aaatgtattt ccaataattt atcatttaat tttttaaagt
   102961 catatacagg ttgagggata ttaaaatctt taattgtata tggacattta ttagagtcta
   103021 ttaatgaata tatatcataa taattgttgt cctctcttaa aaaatccata aatgattttg
   103081 taaagtcaat atctttttgg ctatttaata atttgaataa gtatttataa aaatctcttt
   103141 catcaagctt taaaaaattt aatggaactt ttatgtcttt tatatttatt ataagttcac
   103201 tatatggaac tataccactg catacaaatc catcaaaatt atctacttgc tcatagtata
   103261 tattaggtaa attattaaaa ggattctccc ctttgagctc aataaatgta atttcacaag
   103321 tatcatttaa ttctttaaga gcttgtttaa acttatctga cataaaataa gatgttgtca
   103381 aaaaaccaat tttatatttc ataaaacctc ctttaaaatt tcgagagtat tgtaactaat
   103441 caatcaattt ataacctcat tttataatag tagataaaac gcgtcaattt attttacaaa
   103501 aggataattg aaagaaaaat cagaaaatat aaaaaagact gaaaaatatg ttgactgtca
   103561 agaataattg tgctattttg taattaagga ctagtctttt aagatttcct aaaataaact
   103621 taggttttag gaaagaaata cattttattt gaaaataaag gagaagatta tgaatacata
   103681 tttaaatgaa atttctaagt ttgttgatga gaatagagaa gaaatagttt cattatggaa
   103741 agagattgtt aatatggaaa gctatacaca ttgtaaagaa agcgtaaata aattggctaa
   103801 gagattaaag tttgagtttg aaaaagaagg tttagattgc gaattagtag atgttggaga
   103861 taatggtagt acattgatag gtacacttgg ttctaatata aataaaaagc ctataatttt
   103921 ttcaggccac atggatactg tctttgaaac aggtacattt ggagagaatc catttaaaat
   103981 aatagaagga aaagcatatg gcccaggtgt tttagatatg aagggtggta taataatttc
   104041 cttatatgtt attaaagctt taaataaaat aggatacaaa gaaagaccaa taaaaatggt
   104101 attttctgga gatgaagaga taggacataa ggattcagca ggtgcagatg ttatattgag
   104161 ggaagcaaaa ggtggtcttt gtgcttttaa tatggaaact ggattagtag ataatagttt
   104221 gtgtgtaggt agaaaaggaa gaatcggatg taatatacat gtaaaaggtg tagaaacaca
   104281 cgcaggtaat gattttgaag gtggaagaaa tgctatagaa gaaatggcta ataagatact
   104341 acgcatacaa aaattgacta atttagatgt tggaactaca gtaagtgtaa gtgtgattaa
   104401 gggtggaaga gtggaaaatt ctattccaga agattgtagt ataaaagtag accttagatt
   104461 tgaaaaagta gaagaaatgg agaatgttaa agaacaagtt agagagatat gtaaagaaac
   104521 ttacatagaa ggaacttcta cagaagttaa ttttataagt gaaatgatgc catttgaaac
   104581 tacagaagat gttatgagat ttcatacatt tgtaaatgaa gtgtcaaaag aaaatggatt
   104641 tggagaatta aatgctaaga gacttggagg tagttcagat gcaagttatt taactattgc
   104701 aaacgttcct acaatctgtt catttggtgt aagaggggaa tggaaccaca catcaagaga
   104761 atatgcagta gtagattcta tgtttgagag ggtgaaatta atttctacag ttattttaaa
   104821 cttagataaa tttgaggtat aaagggggat tttatatgga tgtaacagct ggagataata
   104881 aggtaacatg gaaagggtat ttatctttat ttgtattgat agtattattt tcaggagtgt
   104941 ttaaagatag tcaaggcttc cttaaagcat tagattttgc taatctgaca ggttcatttg
   105001 gtactattgc agatggtgta gactttatgg gtaaaggagg aacgggagca aaagatggtt
   105061 tcttatttgc tctgactttg attccaactg tctgttttgc tgtaggtctt atagatgtag
   105121 ttgaatctat gggaggaatg aaagcggcat caaagatatt taatccattg cttagacctc
   105181 tgcttggtat acctggaata gcaggaatag catttgtatc ttcatttact agttcagatg
   105241 tagcctcaat aatgacgaaa gaattatttg aaagtgggga aataacagat gatgaaagaa
   105301 ctatatttgt agcatatcaa tatgctggtt cagctgttat actgaacaca ataaatactc
   105361 aagctccact tttaccaata gcattattgg cattaggtcc aataatcctt atagagatat
   105421 tctgtaaaat acttggtgct aatctagtta gattaatcat aggtgtaaga aataaaaaga
   105481 ataaggctaa ggaggctgtg tagtatgagt caacaaaata ctggaaatgc aattgtaaat
   105541 agtaaaccta agaaaactgc tgttgagata tttatggggg gagcaaaaaa aggtttttac
   105601 ataggtgttg aacagatatt accagccatg ataatgggtt atgtaatagt gcagttttta
   105661 caattaactg gtttagttga tattttagga aatatttttg gaccagtaat gggtattttt
   105721 ggactacctg gggaatctgt tgtagttttg atagcagcat tctttgctaa ggcagcagga
   105781 gcagctacag ctgcaaactt atttgcacaa ggtctaatca ctgcaccaca agcaaccata
   105841 ttaattatgc catgtatgtt aatgggtact ctagttggtc attatgccag aatagtgctt
   105901 gtagcaaatg ccagtactaa gtatagaatg ttactgttgg cagttcctat atttgatgca
   105961 atagtgggga tgttaatagt aagagtttta ctcactgtta tgggattaat gtaaataaca
   106021 taaaattata gcctaattat aaatgatata taagaattaa tatatgcaag aattgatgaa
   106081 tagtaattga tatatagtaa taaaataata tagtaattaa tatgtatatt gtatatcaat
   106141 taaaaaagaa gagagtatct caaagtgaac tttttagttc atgagatact ctctttgtat
   106201 gaaatcaagt atattttcat aatttcaaca atgaaagaga ggcttatctc tattttgaga
   106261 cagcctcttc ttttaaattt atatttctag aatttatgtt ttttatttat ccaacattaa
   106321 cattagttat tagaaataat tttaagaaaa atatactttc atgttaatat cagaataaat
   106381 gtgtttttaa aggatgattt gttttgaatt ttcacgaata tctacttcta tgactttttc
   106441 tattgtatct cctctaaaac ctaataaatt acttgtcaag tttgcagtgg aacaagaatg
   106501 attaggtata attcttattc tatcaccaat ttttatatca gtttcaccat ttactttaat
   106561 ttttccaact tcttctgaaa gtgaatcaat agtaagttct ggatgtccac ataccctacc
   106621 ataaccaaca atactactat ttccatgtgc acctttatca agtccaaggc acttacttcc
   106681 acaatcaatt aaatagtatc cactgctatt ttttgagatt acagtgcaca caacagtaag
   106741 agcacacata tcttcagtag cacaacctaa acctatctgt atagcatcat agtatacata
   106801 gtttccaggt cttacagcag ttatagtttt agaagcagct tcagattcaa ctgttggagt
   106861 actaccagaa gcgacaattt ctatattaaa tccattatca gttagagctt tgtatgcttt
   106921 ctccatagaa gaatcttctt gaacacaaac atctggaaca ccttctggag aactacaacc
   106981 atacacttga cctggatgcg aacttatacc aacaatcttg atgttttcta gcttagaaat
   107041 ttcagtagca agttcaacca ctttttctgg ttcaacccca aaacggtgta agccacaatc
   107101 tacaataata agtagcttgc actctatttt tgatttagaa aaagcttcac tataagcctt
   107161 agcacattct atattatctg tagcacagat taaatttatt tttgatgcca tagtcacaat
   107221 tctatttata tttacttctc ccatgtaagg ataagccaac ataatatctt caaaacctgc
   107281 ttttatcaga gcttcacctt catcaagtgt tccagctaga aaaccactag cacctgcatt
   107341 tttttgaagt ctcgctatgt aagtactttt atgtgtctta agcataggcc aaagttgttt
   107401 attattattt gtacaaattt gttgaatttt atctatattc ttttctaact ggtctaaatc
   107461 tagcaaaaaa tttggagtag cgacttctga aattttcatg ttatttacca cctttcaaca
   107521 aaagtaaatt aactataagt attataatta ttatattagt aatatcggct ttataatatt
   107581 aatagcttat aattatatta tagaactagc gttaacagag agcaatattt atttgtaata
   107641 attagaattt tcaataagtt agtgtagttt taaattattt atataatata tttttaattt
   107701 tatgcaaagt ttatttaaat tagtttgagg atttattaat agggtattat tgaatgagta
   107761 aaaaagtgat gtttacatag aataatcaca ctataaatta atttagaacc taaaaaatta
   107821 attgagcaaa ttggaaaaga gaaggataaa aaagatattt ggatagttgg tggaggcgat
   107881 atagtaaaat tatttatgaa agataactta attgatgatt attatatata tatattgcca
   107941 ataatattgg ggagagggat ttcactattt aagtctggta tagacaagac taatttgaat
   108001 tttaagaaag ctagtaatat tggagaactt gtaaaattgg aatacagtaa aaaacaaaaa
   108061 taaattacat gccaatttgt tacaatgtta tgaaacgaag catttaaaag acttttggct
   108121 atatgaattg acattacttg tcaaatatgt taacatataa gcgacttgtc ggagggtgta
   108181 ttaaaaagaa tatgctggag aagagagtgc gttaactctt ttctcctttt tttataaaat
   108241 taagcattta taaatttagt attattacat gattacacta tctcaaaaat taagaaagga
   108301 gaaaaatatg aaattaattt taagttattt aaagaattat aagttattaa tagtattaaa
   108361 catactggct atatttagtt ttgcattagt cgagttgggg attccaacta taatagctaa
   108421 aataattgac aatggtattg caaatcagaa tatagcttac ataaaacaaa tgggaatagt
   108481 gattgttatt atttctatta taggggttgt aggtagtata ttgttgggtt attgttctgc
   108541 taaggtatca acaagtgtaa ccagagatat aagaaatgac atatttgaga aatcacaaga
   108601 attttcacat actgaataca ataaatttgg aatttcttca atgattacaa gaacaacgaa
   108661 tgatgcattt caaattcaac aatttgttaa tatactacta aggactgcct tattaactcc
   108721 agttatgttc attataagta taataatgac aattagaacc agtgtggaac tttctatagt
   108781 attggctata tcagtacctt ttataattat tggagtagca ataatagcaa aagtatctca
   108841 ggcaatatct tcaaaacaac aaaaaggact agataaatta aaccttatat cgagagaaaa
   108901 tttaactgga ataagagtaa ttagagcttt tggaaatgat gattatgaaa cagagcgatt
   108961 tgaaaaaaca aatacatatt atgctaatgt ttctaagaaa ctatttaagc ttatgtcaat
   109021 tactcaacca gcattctttt tactgttaaa tatagctgtt ttggctgtat tttggatttc
   109081 aagtgagaag ataaatattg gagagcttca agttggacag ttggttgcat ttttggaata
   109141 tcttttccat gccatgtttt caattatgct tttttcaatg gtatttatta tgtatccaag
   109201 agcagaggta tctgcaaata gaataaaaga actattaaat gaagaaccat tgataaaaaa
   109261 tcctgaaaat ggaattaagg atactgaaaa taagggtatc atagaatttg ataatgtaac
   109321 ttttacctat ccagatggag aagcttctgt acttaaggat atttcattta ctgcaaaaac
   109381 aggtgaaaca gtcgctttta taggaagtac tggtagtggg aaaagtactc taattaactt
   109441 gatacctaga ttttatgatg taacagaagg tagcattaag ataaatggag tagatataag
   109501 agaatatgat ttaaaagctt taagaaaaaa gataggattc atacctcaaa aatcactgct
   109561 ttttactggt agcatagcaa ataatattag atttgggaaa cataaggcag gagagtcaga
   109621 attagaatat tccgcaaaag ttgcacaagc atatgagttt atatcaaaaa aacctagaaa
   109681 gtttgatgaa ttgattagtg aaggtggagc aaatgtatca ggaggtcaaa aacaaagact
   109741 ttctattgca agggctatta taagaagacc tgaaatatac atttttgatg atagtttttc
   109801 tgcacttgac tttaaaactg atgcaatact tcgtgctaaa ttgaagaagg aaacaaaaga
   109861 tgcaattgta ttgattgttg cccagagaat tagttctatt attgatgctg ataagattat
   109921 agtactcaat gaaggacaag ttgtaggaat gggaactcat aaagaattat taaaaaactg
   109981 tgaaatatac tatgaaattg caacatctca gttaaaaaag gaggaattag aataatgaaa
   110041 aagtctaaag gttttaagaa aacaattggt agacttcttc catttgtaaa gaaatataaa
   110101 ttttccttta ttatagctat tatatgtata atttcagcag ctactatgaa tgcacttgca
   110161 cctaaaactg aaggattgat aataacacaa ttgactaaag atgtaattag tatcgcaaaa
   110221 ggagtaccag gggcttccgt aaattttgat tatgtaacaa aaatattggt gattttagca
   110281 tgtatatatt ttgccaatgc aatttttacg tatacttcaa gttttctact tacgaatgct
   110341 attcaaaaca caatgagaga tttaagaaat gaagtcgaaa ataaaataag aagattgcct
   110401 attagttatt ttgatagtaa tagttttgga gatgtattaa gtcgtatatc aaatgatgta
   110461 gatacaatat caaatgcatt gcaacagagt tttatgcaaa ttgtaaactc aatcttagtc
   110521 ataattttgg cactttcaat gatgtttaca attaatatat atatggctct tatagctctt
   110581 tttataattc caattagtta ttttgtatct aaatttgtag taaaaaaatc tcaaagtaga
   110641 ttttcattgc aacaaaatgc tcttggaaaa ttaaatggga aagtacaaga aatgtatact
   110701 ggatttaatg aaataaaact atatggtaaa gaagaagatt ctataaaaga atttaaaaaa
   110761 gtaaatcaag aactttgtga aaatggattt aaggcacaat ttatatcaag tatgatgaat
   110821 cctatggttt cattagtaac ttactttgga attgcagctg tggcagttgt cggttctata
   110881 tatgcagtaa gtggaggaat aacagtagga aatttacaag catttgtgcg ttatatatgg
   110941 cagataaatc agccactttc acaaatgact cagttatcta cagtaataca atcttctttt
   111001 gcagctatag aacgtgtatt tgaaatttta gacgaagaag aggaaatacc tgatgttgaa
   111061 aatccagtta agatagaaaa tgtaaaagga aatgttacat ttgagcatgt taattttgga
   111121 tatggagaaa attcaacttt aatagaagat ttaaatgcag aagtaaaaag tggtcagatg
   111181 gtagctattg ttggacctac tggagcaggt aaaacaacat taataaactt attgatgagg
   111241 ttttatgatg taaagaaagg tgctattaaa attgatggag tagatataag agatatgaaa
   111301 cgtaaagatt tgcgttcaat gtttggtatg gtgcttcaag atacatggtt atttaatgga
   111361 accatttttg aaaatataga atatggtaga tttggggcta ctaaagaaga aattatacaa
   111421 gcagcaaaag tagcaaatgt tcatcacttt ataaccactc ttccagatgg atacaatatg
   111481 tttttaaatg aagaagcatc taatatatct ctaggggaaa aacagctttt aaccatagct
   111541 agagctttta tatcagaccc ttcaatattg atacttgatg aagctacgag ttctgttgat
   111601 actaggctgg aacttatgct tcaaaaagca atgagaaatc ttatgaatgg tagaactagt
   111661 tttgttatag cacatagact ttctacaatt cgcaatgctg acttgatttt agttatgaat
   111721 aatggaagta ttatagagca ggggaatcat gatgaattaa tggaaaaggg tggattttat
   111781 gagaagcttt ataatagcca atttgcagac aaagaatcag aatagataac ataaactttt
   111841 gtataaaatt ttgtatcaaa ttcaaatatt aatcatataa ttaaaaagag tatcagtaag
   111901 ttgttttttt atagatttac tgatactctt tgattttaag actaaaggta tttatgattg
   111961 gtacttataa ttcacaacta gtcttgttac atctgataac cagaattaca gtacttttct
   112021 tttttacctt tttgttctct aacatataac aattcgctta acttatcaat gtaataacca
   112081 tcatcactta tgcgaattaa actagtcaga taatatccat ctttgcttct aggaatcttt
   112141 ttatttattg ctaaatcaat agctgtcttt gctgcttcaa aatgctttaa atgtgtatga
   112201 ccttcttcaa aactctttct agtattataa actacataac cttttttaac ttgaaaaact
   112261 ataaattctt tcttttcata tattttatta aacattcaat cagcccttct caagatagtt
   112321 ttatagcata acattagaag cttctaaaaa attttacaaa gaacataaat attttataaa
   112381 ttataaatct aaaactataa tttataaaga taactttctg attatttata tgataattca
   112441 tatagattaa aagtaaatta tctttaggtt aaacaaaagt aaaataaaag actagttata
   112501 atatttatat gaaaaagtac aaaatatagt atatgaatat agaaaattta aattatttat
   112561 ttacagtttt tatttccata agtatattta ccttcagata ccttgtcatc atggaaatat
   112621 attctttcac aacttttatc tccccataga atgttttttg ttattttatg ggaagtatct
   112681 cctgtaaata cttcagctac agtagtatct gtaacatcac agtaaagaga agcaaatttt
   112741 ttaaaccaag gattttcctc aaatcttaaa agccaggaag ctccataggg gcaatgtaac
   112801 tcttcaaatt caggaaccca tcctagaaat ggaacatcag ttgtgctaat aatattgtct
   112861 gcaattaatt catctccatt ttcatgagct ctctctctca tagcaatagc tctttcttca
   112921 gacctttcaa ataaaacttt tcttaatatt tcgctagttt tatcttcacc aaactcttca
   112981 aataacactt tggaaaaata aaaatataaa tcaccaaaat gtttgcatgc catacgaact
   113041 tcttcaatag cataatcttt gtcaatagtt tcattagtta caacatcttc gttcaaaaaa
   113101 atcactcctt agaataagta ttagttacaa tataattata gaatattttt tataaattag
   113161 gaaattaatt tgagatagat atatttttaa taaatgaaag tataatacta aaataactta
   113221 ttgttacaaa aatcttctaa attaatgtat ttaggagttt ccatatgaat gagagtagtt
   113281 ctgtaaatat cttcaataca tccatttgca atattattaa aaatatctgt gtgctctttt
   113341 aatgttgttt caagccttcc ttcatgtgac aatgaatcga gagctaattt ttttattctg
   113401 tacatataat tgttaaacat tttgtcaaat tcagtatttt gagcatatga aactatagtt
   113461 gtgtgaaata atgtatcgta ttctgcaaat gagtttaaat ttttatcacc taataaaata
   113521 tctttttgtt tatctaaaag atgttttaat ttacttatag tttctactgc tctaggttct
   113581 ttgtattgac ttgtaattaa aaaagtacaa aatccttcta ttgcagagcg tatttggaat
   113641 atctctacaa tttcatttgc tgtaatttga tggattctaa atcctttgct tggaattata
   113701 tctataaatc catcttgact aagtctttga agagcatctc ttataggtgt tctagagata
   113761 cctatttcac tagcaagttt tgtttcagaa tatatttcat tttctatcat ttctccagat
   113821 agtatcaatt cttttaagta gtcatatgct tgttcttgta atcttttaaa tgtagccata
   113881 cttaataata cccccctaaa caatataaaa atacaaaaac ttatataatt ttaagcatac
   113941 aacatagtga aaataaggtc aatcttttgc aatttaaatt gcagataaga ttaaaaaata
   114001 taaaaaatta ttgaagtgtg aagcatgatt aacattaaag gcagattaat taaaactaat
   114061 tgaaattagt taaaatacaa aactgtaaaa gtagtatatt atatttgaaa acaatagtat
   114121 gtattaaaac ttatatagga tgactaaata taataaatga ctttaaaaat tactatttat
   114181 tgttaaaata aatactttta tattttatat tgaccggtat actggtatgt agtatactct
   114241 aaaacataaa aaacgttttc aaaaatgtga agatatggag ggttataaaa tgaaattggg
   114301 atttattgga ttaggaataa tgggaaagcc aatggcaaaa aatttattaa aagatggatt
   114361 taatcttttg gtgtatgaca ttaataaatc tgctgtggat gaacttatat catgtggagc
   114421 aaaatacgca agtgttttag aaatgggtca agaatgtgat attgtattta caatccttcc
   114481 aaatggaact attgtgcagg atatattgtt tgggatggat ggattggcaa aaactttaaa
   114541 agaaggaagt atagtagtcg atatgagttc agttactcct acagaatcaa tattgtgtgc
   114601 aaataaatta aaagatatgg gcttagaatt tatagactca ccagtaagtg gaggggagcc
   114661 aaaagcgatt gatggtacac ttgcttttat ggctggtggt aaggaagaaa tttataagaa
   114721 agtagagcca ttttttaata taatgggaag ctcatctatt ttaattggag ataatggtag
   114781 tggaagtgtt acaaaactta caaaccaagt aatagttaat ttgacgatag cagcagtttc
   114841 tgaggcattt gtacttgcag caaaagcagg tgcagaccca gaaaaagtat ataaggcaat
   114901 aagaggaggc ctagctggta gtacaatatt ggatgtgaag ataccaatga ttatgaatcg
   114961 tgattttaaa ccaggtggaa aaatatctat taatttgaaa gatattaaga atgtaatgca
   115021 aacagcacac aatttagatg taccactacc tatgacaagt caattattag aaattatgca
   115081 gacattaaaa gtacatggac atttggaaga tgaccatagt ggaatagcac agtattttga
   115141 aaagttggca ggtgttgaaa taaaaaaaca caataattaa tatttaaata tatcaatata
   115201 attaaataca tattattagg attagattat ataaatacag cgaggttaag ttatcatagt
   115261 aaaagaaaaa taaaattgat aaataataaa gtagaatgat aaaggggtaa agattatgat
   115321 tacaggatat ggacttttga tagcatttgt tatatctata ggaattttac ttgtatcgat
   115381 tattaaattt aaagtaaatc catttttggc attactgata acatctataa ttacaggctt
   115441 tatggttaga atgcctataa atgaaatatc aaccacaata tcgactggat ttggaaatac
   115501 attaggtagt ataggtattg taattggact tggaataata tttggaaata ttctttcaga
   115561 atcaagagca acagaatcta ttgcaaaggg gttgttagct aagactggag aaaaaaacag
   115621 tgctttagca gtaactacag caggtttttt aatttcaatt ccagttttta tggatgcagc
   115681 ttttgttata atgatgccta taattaagta tgtttcgaga gtaactaaga aatctctaat
   115741 ggtttttgta tgtgcattag gagttgggac tatagtaggt catgcacttg taatacctac
   115801 accaggacct ttagcagttg cagcaaatgt aaatgcaaat gtaggtagtt ttatacttta
   115861 ttctataatt gttgcttttc cagcagctct tataggtgga tggatttatg gaaaacgttt
   115921 tgaaaaatat ccagcttatg ctattgatga gaatgataga gaaaaaaatt tagagcaggg
   115981 aaaagatagc ataaaaattg aagatgatga ttcttctaaa gcaccaggtt ttggaatttc
   116041 tatgttttct ttattgttcc caatacttct tatacttata tcaaatgtat ttagtatgtt
   116101 cttagaaaaa ggttctacaa tgagtggagt acttgcattt ataggagata aaaacatagc
   116161 aatacttctt ggaatattgg tggcaatagg atttttaaag aaatacataa ataaacctat
   116221 gggagatgta gttattgaag ctgctgattc agcagggcta atattattga taacaggttc
   116281 aggtggtgcg tttggcagtg ttataaatgc aagtggtata ggtaacttct tagttgatac
   116341 tatgtctggt cttagtatat cagttgtagt gcttggattc ttattaagtg ccttgcttag
   116401 aatttctcaa ggttctgcta ctgtagcctt agtaacaaca tcatcaattt taggacctac
   116461 aattttggca actggaatgt caccagtttt agtagggctt gctatatgtg ctggaggagt
   116521 tggtttctcc cttccaaatg attctggatt ctgggtactt tcaagattta gtggattatc
   116581 agttaaagat actttaaact cttggacaat tggaggaacc attgctggag ttgtagcatt
   116641 tataatgatt ttattgctta gtgttataaa tggaattata ccacttccag gtctataaat
   116701 aacaaactat tgtttatatc atataaatta catttagact atacaaatta cataaagggg
   116761 cgttttaaat gagagaagta aaaccaatta gcatagatat acttaatact tttaaacaag
   116821 tagatgagga cagattaaat aaacttcttg cagatgagct taagcattta gatagaaaaa
   116881 ttgttgtatt agatgatgac ccaacaggtg tacaaacagt tcatgatatt tctgtttata
   116941 ctgattggga taaggatagt atggaacaag gttttaatga gaaaaatagt atgtttttta
   117001 tacttaccaa ttcaagggga tttactgttg ctcaaactac aaaagcacat aaagaaattt
   117061 caaagaatat tgtggatgta tcaaagaaag ttaataagga ttttataatc ataagtcgta
   117121 gtgattctac tatgagagga cattatcctc ttgaaactaa tttattaaaa agtgaagtag
   117181 agagattatc ggggaagtta tttcagggtg aaataataat gccatttttt aaagaaggtg
   117241 gtaggtttac tatagataat gtacattatg ttaaagaagg agaaatactt gtaccagcag
   117301 gaatgactga atttgcaaaa gataaatctt ttggatataa atcatctgat ataggtgagt
   117361 ggtgtgaaga aaagacaaat ggaaagtaca aatctagtga tatgatatat atttcgtcaa
   117421 aagaacttag agagctaaat attgaagcta taacagaaaa acttaaaaaa gctgaaggat
   117481 tcaataaaat tattgtaaat gcaaccgatt atgtagatgt aaaggtattt acaattgcgt
   117541 ttatacgagc agtaaatagt ggtaaggaat ttatgtttag aagtgctgct gccataacaa
   117601 aagtacttgg cggagtgagt gacaaggaac tacttactaa ggatgaatta gtatcaaaag
   117661 gtaataccaa tggaggaatt atacttgttg gttcacatgt gaataagact acccaacagt
   117721 tagaagaact taaaaattgt aaatatccga tagaatttat agaatttaat caacatttag
   117781 ttcttcaaga aaatggtcta aaaaatgagg taaaaagagt tataaaagtt gtagaggaaa
   117841 aaataagcag gggtaaaact gttgctgttt atactagacg agagcgtttt gacttggata
   117901 cgaatgataa agataaacag cttatgattt ctgtagaaat atcagatgca gttaccagta
   117961 taattggtat gcttaatgta agaccaaatt ttattatagc taagggtgga attacttcta
   118021 gtgatgttgg tactaaagca ctaagagtaa aaaaagctac agtaatggga cagataaaac
   118081 ctggtatacc agtatggatg acaggcaaag aaagcaaatt tcctaatatg ccatatataa
   118141 ttttccctgg aaatgtggga gagattagca cacttagaga atcagttgag atattgatgg
   118201 ggtagtatat tagtgtattg aagtttaaac gcttaaattt actgagttaa aattaaaata
   118261 aactaaaatt ataaattaag attaaaaata atagtatatt aattagggtt tagagtattt
   118321 tacaaaaaat attctaaacc ttaatcttat gtattagtat ttttattatt taacttatgt
   118381 gtttatttta ttatttatct tttttaattg atttaatatt ttctttgatt ttatttaaaa
   118441 tatctgtatg cttattagag cttatgttgg ggaatgcttt gattatacgt ctatgaagta
   118501 atttgtggtt agacagcaaa gtattaagtt tattttttag ctcatcaata cgatttttag
   118561 catagcgata attttctttt tctttaagta tttcaaacct atcttccaaa gtatccagtc
   118621 tattttcaac taaagattca agtttgtttt ctatagtttc ttgtgtaata agtttgtagt
   118681 attctttctt atcttttaat tccttaatta taagattgat ttgttttaac ttaccattta
   118741 attgtaaaat tgtatggact gtgataacta aatctaaaac aaaataaatt tctatagata
   118801 tagcaaatat aaatagcaca tttttggaga tagagttaat aaagtcaacc acaataggat
   118861 gtactataag cattacaatc aatgataata caccaaacat aagtgagttt tccagacaaa
   118921 ctcttccatg aatattaaat ttatgtttag aataatccca ccaagtcata ttaaatattt
   118981 tttctaaaat aaagctcgta caatactcca ttatgctagt tataattata ctaaacaaaa
   119041 ataacaaagg aatattgtgt acaaaaggag tcaaggtagc aactattgct aatgctccaa
   119101 atccatatat agggcaaaat ggaccattta aaaaacctct atttacaaat tgtttttgta
   119161 aaactgaaca atatgtagtt tcacaacacc atcctataaa gctataaatt acaaaataaa
   119221 gaaattgaat ataaaatgta ctcataagca cctcatttct agttagtata acactatata
   119281 ctcgatattt tatttttatg attaatttac taaattcaat ttacatattg attataccaa
   119341 tttatagaaa tttatcaaat ttaattacag ttagaacatt ataaacatgg ttataataat
   119401 gaaattttat ttaaaataaa taagggtgtc aagtataatc aaactaatag ttgtagatac
   119461 tctacactat gttagtttaa ttacatttga cacccttata tttatactat gactatttac
   119521 attcgaagct agagcaacat gtttcaatat aaagatttac tctatcagtt tcaggagcaa
   119581 ccaatatatt atcaagtgta cataagctac catctttgtt gtatttacaa ttttttacag
   119641 tacaaactaa ttcctcacaa tttctattat taacgttgct agataaatta ctataaatag
   119701 attcatctaa aaatgaacta caacaagtat gtctatcatt gtgagctttt tcaccattta
   119761 taaaaatttt atctgcataa catatatggc tgttgttatg tgaacagtta attacattac
   119821 agtttattct ttccaaagtt attacctcct aaacgattat ttattataaa ttatgtccat
   119881 ataattacaa gaatataacc attaagagaa aactaccttt tagaaaatat ctattcttag
   119941 agtaatttga aatataaata tattttcttc taaaatttac ctaaattgta taaaaactta
   120001 cagcttggag aaaataatag aaaaaggagg cgtaatcaat gtttgaaaag aagaaaaaag
   120061 aattatttcc ttggaaaata tctgccttaa tactggttgg agtatttgta ttaagtagcg
   120121 gagtttatat agggacaaga ttaaaacaca atggagttca aactggtgaa gttgtaagta
   120181 ctagtgcgaa tatgaatgaa aagtcaaaag aagcttttgg attaaataaa aattgtgaag
   120241 tttggcttca aagtgaaggc gaaaatgaaa ctaactataa gagaacactt acaatggcag
   120301 gaatagttcc agagtcatta ttagataaga cgaagtcaga aatagtatca tattttaaaa
   120361 aagaatatcc aactaaaaaa ataaagagta tggataaaaa tgaaatcata ttggtagaat
   120421 ctaaatatag tgataataaa gatgtacaag caatggatgt tactataaaa ggtaaatata
   120481 ctattgaaaa tgataatgga aatatagcac tatataaata tgatgatagt ggaactaaaa
   120541 cattagtaga aaaaacaaaa ataagagtag attcacttcc taaaacagtt caagatgaaa
   120601 tcaaaaaagg tgtagttatg gatactgaag aagaggccta ttcaagatta gaagactttg
   120661 caagttaata gtaaattaat attattttaa gttaaatact aagtaagtta aatactaagt
   120721 aaattaataa taaataattt aatattaaat agattagtat taaaattgta gtcacattta
   120781 attcctataa aaatacaata atttatttgt aataaatata aaagttatat tgaggtaaaa
   120841 tcttgctttg atataacttt tttatttgat tttatatttt acatagagca ttttatgatt
   120901 tgttaatatt atttatgata taatgattta gaacataagt ttttatgaga aatacatttt
   120961 ggtatttctt ttatttttag ggggaatttt aaaaaatgat aatattgggg attgacccag
   121021 gtatagccat agttggatat ggtataattg aatacaaaaa tagcaagttt aaagtaatcg
   121081 attatggagc agttacaaca cctgcccata tgaatatatc gagaagattg gaacttgtgt
   121141 ataaaggaat tgatacaata gtaaagaatt acaatataga tgaagttgga atggaagaat
   121201 tattctttaa caagaatgta aaaacagcta taacagttgc acaagctaga ggtgttacta
   121261 tgcttgcatg tgctcataat gggaagcctg tatatgaata cactccactt caagtaaaac
   121321 aaggtgtagt tggatatggg agagcagata aggcacaagt tcaacagatg gtaacttcat
   121381 ttttaagtct aaaaaaagtt ccaaaaccag atgatgttgc agatgcttta gctgtggcta
   121441 tttgccatgc tcattcaaac aaacttgaaa aaactctaaa gaatataggt ggtaagtatg
   121501 tatagttata taaaaggtac agtagaagaa atttatatag acagtatagt tgttgaaaat
   121561 aatgggatag gatataaaat aaatgtatca tccaatacaa taatgaattt acaagtggga
   121621 gaagccacaa aaatatatac taaattaatt gtaagagaag atgatatgag tctttgtggt
   121681 tttgtaagta gggaagaact taagatgttt gaattactaa catctgtatc taaaatagga
   121741 cctaaggtgg cgctttcaat actatcattt gcatcaccag cacagttagg agcatatatt
   121801 ttaagtgaag acattggaaa attatccaaa gctcctggtg ttggtaaaaa gacagcagaa
   121861 agaatcgtct tagagcttaa ggataaggta gacaaaaata acatagagtt tgaaccaacg
   121921 ttattatcac aaaaacctac cttgatatca caagatgagt ctgtagatgc acttgtagct
   121981 ttaggctata ctttgtcgga atcaaaagag gcagttcaaa aatgtaaaaa agatggtatg
   122041 aatacagaag ctattataaa gaaagcactt acatatataa tgagtaaatc tttgaaatag
   122101 tatttggatt ttataatatt tggattttaa aacaatattt aaggagttta tgtaaatttg
   122161 aaaatatata aagtagattt tcaaaagtat gagaggaggg gtataaatgc aaggttttga
   122221 agatgaaaat aggataataa cttctacaat gaagatggaa gatatagata tagaaaacag
   122281 tttaagacca aaaactttag aagattattt gggtcaagaa aaatccaaag aacaacttag
   122341 tatatttata gaagcagcta aatcgagaaa tgagcagtta gaccatgtgc ttttatatgg
   122401 accaccaggt cttggaaaaa ctacactagc aagtataata gcaaatgaga tgggggtaaa
   122461 tttaagaatt acgtcaggac ccgcaataga aagagctgga gatttggcag ccatacttac
   122521 gaatttaaat gaaaatgatg ttttatttat agatgagatt catagaatca atagaagtgt
   122581 tgaagaagtt ttatatccag caatggagga tttttgccta gatataataa ttgggaaagg
   122641 gccatctgct agaagcataa gacttgacct tcctaaattt acacttattg gagctactac
   122701 aagagctggt atgcttacaa atccacttag agatagattt ggtgttattt gtaaattgga
   122761 ctattataca gttgatgaac tttcaaaaat agtacttagg tcttcaagca tcttagatgc
   122821 agagatacag tctaatggag cattagaact tgcaaaacgt tcaagaggga ctccaaggat
   122881 agcaaataga ttactaaaaa gagttagaga ttttgcacaa gttagagctg atggaaaaat
   122941 aactgataag gtggcaaaag atgctctgga acttttagga gtcgatagtt tgggtctcga
   123001 ttttgtagat gagaagcttc ttatgactat aatagaaaaa tttagaggag gaccagtggg
   123061 tttagataca ttggcagctt ctatcggaga agatagaaat acaatagaag atgtatatga
   123121 gccatatttg cttcaattag gatttataaa tagaggtcct agaggaagag tagccatgcc
   123181 attagcatat gaacacttaa aaattccata tcctaatgaa aaataaaaat agattatacg
   123241 agtatttata aaataaaaga gtcattaaat taaaatattt ctaaaatggc taaaaattca
   123301 aacatatcca caaaatggta attatatctg tagatactgt ggataaacac gataaaaatt
   123361 gtgtgtattg tatctatata ttgtggataa gacatgtata tcgtggaaaa atatctatat
   123421 attgtggata tggtgtctgt taaaaatagc aatttcttga tagattatgg taatattgtg
   123481 gaaaataagt tgtttttttg atattattgt agctggagaa attttaagag aggaagttta
   123541 acattgaaaa caagtgattt taaatttgac ttaccacagg aacttatagc tcaagttcct
   123601 atagaagata gagctagctc aagattgatg gtattagata aagagacagg taatattgaa
   123661 cataaagtat ttagagatat aatagaatat ttaaatccag gagattgctt agtattaaat
   123721 aatactagag ttataccagc tagattaata ggagagaagc ttgaaactgg aggtaaaata
   123781 gagtttttat tattaaaaag aacagaggaa gatacttggc aggctttagt aaaaccagga
   123841 aaaagagcaa aagtagggac taaattttct tttggaaatg gaaagctaat tggagaagtt
   123901 gtagatttat cagatgaagg ttcaagaatt ataaaattcc attatgatgg aatttttgaa
   123961 gaaatattgg atgaacttgg aaatatgcca ctacctccat atatcactgc tagactagat
   124021 gaaaaagaaa gataccagac tgtttattca aagcataatg gttcagcagc agcacctaca
   124081 gcaggattac attttacaga agaattgtta aataaaataa aagaaaaagg tgtagatata
   124141 gcctttgtaa ctctacatgt tggtttagga acttttagac cagtaaaagt agaggatgtt
   124201 ttaaatcaca agatgcattc agaatattat atggttagcc aagaagcagc tgacaaaata
   124261 aatagagcaa aggaaaatgg aaaaaatgta atatgtgttg gtactaccag ttgtagaact
   124321 atagaatcag cttgtaatga ggatggaaag atgaaagaaa ctagtggatg gacagaaata
   124381 tttatatatc caggttataa atttaaagtt ttagataaac ttattactaa ttttcactta
   124441 ccagagtcta cactaataat gttagtaagt gctatttgtg gaaaggataa tgttttaaat
   124501 gcatataatg aggcagtaaa agaaagatat agattcttca gttttggaga tgctatgatt
   124561 ataaagtagg gaggtaatgg atgcatagtt tacaaaaaca aaaaaagaat aaccctatat
   124621 taaagattgc ttttatattt gaacgtgttt tagcagtagt agttctaata gcagtatttt
   124681 taggaactat agatgttcta agacttatgt ggggagcata tatagttgat tttcaaaatc
   124741 cagtacaata cagtcagctt aatgattttt tagcacaaat attactttta gtaataggtg
   124801 ttgaacttgt agtaatgcta tctcttcata taccaggagc atttattgag gcattacttt
   124861 acgcaatagc tagaaaaatg ttgctactgc ctaaaaatga aggtatgata gatgttttaa
   124921 taggagttat agctatagca ggactatttg ctataaaaaa gtttttagta acaaaagaca
   124981 agagtgctct taatataatg agtattcatg atgaagaagc aattaaggaa caacagaaca
   125041 aagaagacga agataaatct atttagacaa taaattatat gaatagctta ttacaaatat
   125101 atcttaagaa ataatgagaa ataaatatga ttaaggagaa ctttatgtac gcagtaagat
   125161 acgaattgat aaagacttgt aagcagagtg gtgcaaggtt aggaagatta cacactccac
   125221 atgggattat tgaaacacca atattcatgc cagttggaac tcaagcaact gtaaaatcta
   125281 tgacaccaga agaattaaaa gagattggtt cacaaataat acttagtaac acataccatt
   125341 tatatatgag accaggtcat gaacttataa aaagagctgg tggtcttcat aagtttatga
   125401 attgggataa accaatactt acagatagtg gagggttcca ggtatttagt ctagggcctt
   125461 taagaaagat aaaagaagaa ggtgtagaat ttaggtcaca cttagatggt tcaaaacatt
   125521 ttctaactcc agaaaaagct atggaaatac aaaatgcatt gggttcagac ataatgatgg
   125581 catttgatga gtgtgcacca tacccatcag atagagaata tgtaaaaaat tctttagaaa
   125641 gaacaacaag atggttaaaa agatgtaaag atgcccataa taataccgac aagcaagctt
   125701 tatttggtat aatacaaggt gggatgtata aagacttaag ggaacaatca gcgaaagaaa
   125761 taactaatat tgatttacca ggatatgcta ttggtggact tagtgttgga gaaccaaaac
   125821 cacttatgta tgacgtgtta gagcatacaa ctccacttat gccaaaggat aaaccaagat
   125881 acctaatggg agttggtagt ccagatgact tagtagaagg tgttataaga ggagtagaca
   125941 tgtttgattg tgtcctacct actcgtatcg ctagaaatgg aactgcaatg actagccaag
   126001 gtaaagtagt agttagaaat gcaacttatg ctgaagactt tactccactt gaccctgaat
   126061 gtgattgtta tgcttgtaaa aactattcaa gagcttatat aagacacctt ataaaagcaa
   126121 atgaaatact gggtgcaaga ttaataacta ctcataatct tcacttttta ttaaatttaa
   126181 tgaaacaaat aagacaagcg ataatggaag atagattact tgattttaga aatgaatttt
   126241 ttgcaaaata tggatatgaa atataggttt tgcactatta attataatca ttttaatata
   126301 taatattcaa tagtactcaa agatagagaa agtaaattgt tatataaaca tttattatga
   126361 tttacaaaag agtataattt acaaaggagt gaaaaattaa tgccacagca acaaataatt
   126421 atgagtatag gtctatgggt agtagtaatc gcaatctttt atttcctaat gattagacct
   126481 caaaagaaaa aagacaaaca attaaaagaa atgagaagta gcctaagtgt aggagacaag
   126541 gtcattacaa taggtggaat agtagctaat gtagctaaag ttgaagatga tgttgtaata
   126601 ttagaattag gaccaaatag aactaaagtt ccatttgaaa aatgggctat aggaactgtt
   126661 aaatctaaaa aagaagaaat agaagaagac taaattagta atttaaaagc cttttctcga
   126721 atatatatta atttgagagg aggttttttt atgggaaaat ctaattatat ttttaaaggt
   126781 ctaggatatg catatataat aactttggct gttttattag tgtataactt atttttgaca
   126841 tttacagata ttggtggaga taatataact atggtctcat catttataac tactatttct
   126901 gcagctatag gagggtttta cacttcaaaa cacatgaaag aaaaaggact tatgtatggg
   126961 cttttagtag gacttttgta catagtatgt atttttttga ctgtgttttt agcacaagaa
   127021 aagtttgtat ttgaaatagg gatgatttat aagttattgc taatatcagc agcaggaggc
   127081 attggaggcg tattgggtgt caactttaaa tagagtttat attaaagtag ttttatgata
   127141 taatcaatag gaaacaatta gaaatggagg cgttgaaaat ggaaaataaa catgtaaaaa
   127201 ctttatctca agctacttta aagcaaagtg ctgcaaaagg tggatgtgga gagtgtcaaa
   127261 cttcttgtca atcagcttgt aaaacttctt gtacagttgc aaatcaagag tgtgaaagat
   127321 agaaaattat tgatttagtt gtttgtaaga gggtatctca aagtgattct tttatcatta
   127381 tgaggtatcc tcttttattt tcaattatta tataaaaata tatattctat ttatgtaaaa
   127441 ttaaatttga tttcttatcg tttaattatg caaaaatatc taatcatata agaacattt
//
LOCUS       DAMJXI010000006       101957 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.006, whole genome shotgun sequence.
ACCESSION   DAMJXI010000006 DAMJXI010000000
VERSION     DAMJXI010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 101957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 101957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..101957
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.006"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            13..1293
                     /locus_tag="PC465_000649"
     CDS             13..1293
                     /locus_tag="PC465_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HDF2647980.1"
                     /translation="MNILGLIVEYNPFHNGHIYHLSKSIEKTNATHTVAIMSGNFLQR
                     GEPALFDKYTRAKIAVENGVDLVIELPTLFACQSAEIFSHGAITILNSLNCINSICFG
                     SEEGNTEILYNIAEILANEPNEFKLLLKKYLDDGLLFPTARANALFDYIHQDKKNNFI
                     QNYSKEQLSKTLNSSNNILGIEYIKNLIHLNSSIKPFTISRVQSEYNSEEIESDICSA
                     TAIRTSLKENTDLFHLKNVIPEKTYNILNEKIDNGFLPMFDDFFFDILKTIILRDMDT
                     LKEYFEVNEGIENRIYKDIFTSEFLHELQLAIKSKRYTLTKIKRTLNNILLGIKKSDM
                     QLIKNIDTIPYIRILAFNDKGREILKEIKNKSEIKIINKFSSISFSLDDTIFKTLISY
                     DIKATNIYNLIYYKNNKDLVKGPMDFYTHPIYVK"
     gene            complement(1556..2947)
                     /locus_tag="PC465_000650"
     CDS             complement(1556..2947)
                     /locus_tag="PC465_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDF2647981.1"
                     /translation="MYKLIDKKDIDFLIDTCGEENVLVGSDINEDFSHDELGGIEKCP
                     EVLVNVLETEQVSKIMKYAYKNNIPVTPRGQGTGLVGAAVAINGGIMINLCKMNKILE
                     VDYENLTLTVEPGVLLMTIGQYVQDRDLFYPPDPGEKSATIAGNINTNAGGMRAVKYG
                     VTRDYVRGLEVVLPNGEIINVGGKVVKNSSGYSIKDLLVGSEGTLGIVTKAILKLLPL
                     PKKSISLLIPFPDLSMAIETVPKIIKSKSIPTAIEFMERDVILAAEEFLGKKFPDNTS
                     DAYLLLTFDGNSTEDIEKEYEKVANLCLENGALDVFISDTQERNDSIWSARGAFLEAI
                     KASTTQMDECDVVVPRDKIAEFIRYTHELQDKLKIRIKSFGHAGDGNLHIYILKDGMD
                     DNTWKIRLKETFDYMYKKSRELSGQVSGEHGIGYAKKEYLHESNSDAYMMLIKNIKLA
                     FDPKNILNPGKIY"
     gene            complement(2958..4178)
                     /locus_tag="PC465_000651"
     CDS             complement(2958..4178)
                     /locus_tag="PC465_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HDF2647982.1"
                     /translation="MSKIVVNQDKITDLKRILEICPFGAIEEKSGIVEISAGCKMCKL
                     CVKSGPKGAFEFIESSKVQINKDEWRGIAVYVEHHNGNIHPVTYELIGKAREMASKIK
                     QPVYCVFVGKDIKDKCSNLISYGVDEVFVYDEDEFKDFRIEPYSKAIENFIDKIKPTI
                     VLVGGTTLGRSLAPRLAARFRTGLTADCTILDIQSNTDLDQIRPAFGGNIMAHINTPN
                     NRPQFATVRYKIFSAPEKIENTTGKITLCKVEKKELKSKIKVLSVKEKNKEVGLEEAE
                     VIVVASRAIKKQEDMEMIYKLADKLNAQVAGTRPVIEAGWIDAKKQIGLSGRTVKPKL
                     IITCGVSGAVQFVAGMQGADYIVAINKDDKAPILDVAHLALIGDIYDIIPKLIEKIEN
                     NKDNNQKYMASAAK"
     gene            complement(4192..4980)
                     /locus_tag="PC465_000652"
     CDS             complement(4192..4980)
                     /locus_tag="PC465_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003457975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF2647983.1"
                     /translation="MEILTCIKQVPGTTSVEVDETTGVLKRDGVDSKMNPYDLYALET
                     ALRIKEEKKANLKVLSMGPPQAKKVIEESFMMGADEGALISDRRFGGADVLATSYTIS
                     QGIKKMGKVDLIICGKQTTDGDTAQVGPEVAEFLDIPHVTNVTKLIEVKDESIVVEID
                     MPNDLQVCEIEYPCLITVEKDIFQPRLPSFKLKLNTKDREIPVYSLDDFEDKDENNYG
                     LNGSPTQVVRIFPPKPNTDKNIVRGNADELSFALVNKLEELKLV"
     gene            complement(4997..6271)
                     /gene="larA"
                     /locus_tag="PC465_000653"
     CDS             complement(4997..6271)
                     /gene="larA"
                     /locus_tag="PC465_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent lactate racemase"
                     /protein_id="HDF2647984.1"
                     /translation="MVKLKVPYSKQGMILEIPDERFLGVLESKSDNYIEHKTQEEIVE
                     ESMNNPIGSNSLEELVKGKKNVVIITSDHTRPVPSRITMPIILRRIRNVNPEIDVKII
                     VATGFHRPSTREELIYKMGEEIVDNEDIVMHISTDDKSMCKVGILPSGGDLYINKLAY
                     EAELLIAEGFIEPHFFAGFSGGRKSVLPGIASAKTIMYNHCSDFIDSDNSRTGKLNNN
                     PIHEDMVYAAKVAKLAFILNVVIDKDKKIIASFAGDVEKAHTKGCRFVTELSKVNSIK
                     SDIVVTTNGGYPLDQNIYQSVKGMTAAEATCKDGGVIIMISACNDGHGGQSFYENVAN
                     ADSPKQLLDKIRSVDRVDTIPDQWEFQILARILSKYTVIMVTDKCNPEMIKKMHMKHA
                     FNFKEALEMANSIVGKESKVVVIPDGVSVIVK"
     gene            complement(6389..7102)
                     /locus_tag="PC465_000654"
     CDS             complement(6389..7102)
                     /locus_tag="PC465_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDF2647985.1"
                     /translation="MFNSIASKKVYEQVIEQIQYKILNGELKKGDKLLSERELSEQMN
                     VSRTSIREAIRVLETMGVIESRQGEGNFICTNIEKTLIEPLSMIFKLNNGTLEDILEL
                     RIILEIEIAKLASKRITSSEVIELKHIIDEMRVETNKKDNNRVLVLLDQKFHSKLATL
                     SKNYLIQSLFMTASKLFDGFIEDAREKIIAEPFNENILLKQHEAIYNAVVENDVELAC
                     EKAKEHMDFISKNYRKNEN"
     gene            7227..8486
                     /locus_tag="PC465_000655"
     CDS             7227..8486
                     /locus_tag="PC465_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YlbJ"
                     /protein_id="HDF2647986.1"
                     /translation="MKKNKIIAFFAPSIIVGVLVLGIILYPNEAIKSAREGFSIWSNV
                     LVPSLLPFIIGANLIVDLKIVDIIGFIINPITRFVFNVSGKSALAFAISTVSGYPVGV
                     SLASEFRSNGQISKYEAQRLVSFCSTSGPLFIIGSVGTGMFQNSNLGYLMILCHYLGT
                     ILVGLFFRNYGNENLPKTKLDLKTNIKNVINIRNSSGNGFFVLFGNAVFNGVNTLLTV
                     GGFVIVFSVVFKILSLFNVISLIASVIYLPLSFLGVSKELCQAFVSGLFEITIGCNKV
                     SSITSSPEILRASLASFLIGFSGLSILAQCCTFLSKTDIDLKLYILSKFAHGVLAAIF
                     IFILYPIANSAVLVSSFADTYNVIYNNLIWFYYLSYYDTIIQIVVIIYLISAVFIAKK
                     HMKTLSTNGKLMRYKNTFFTKKFSRKK"
     gene            8754..9320
                     /locus_tag="PC465_000656"
     CDS             8754..9320
                     /locus_tag="PC465_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2647987.1"
                     /translation="MATRPIEIDEYKKIMELLHTGFTYSENGVEKRFRKNPKVALALM
                     LEANLGLRISDILRLKIGNFKGNMLEINEKKTGKLQYRPVNKNIIESINEHARKYNLK
                     SNDYLVNIKTKAIQKQLRIICKYLNLYNISTHSFRKLYATTQFEKSNNNLELVKELLN
                     HSSVATTQRYIRVTQQAINEASENFFIG"
     gene            complement(9521..10726)
                     /locus_tag="PC465_000657"
     CDS             complement(9521..10726)
                     /locus_tag="PC465_000657"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HDF2647988.1"
                     /translation="MKIAILGYGTVGSGLIDLIENNTSKRDIEVVGILVKNKEKHKYK
                     KYFDKITTDIEDIFDKDIDILVEVIGGLNPAFDYVTRALNKKIHVVTANKDLLAEKGS
                     DLIELANLNNVSIKFEASVAGGIPVLKPLIESLEGNNIKSINAILNGTCNFILSKMYD
                     ENLPYDVALKQAQELGFAEVNPDADVLGYDSARKLSILSTLSYGKIVYWKDLLLEGIT
                     SIDEKDIEYAKKLNCKIKLVARSKYESGEVSGFVRPALVDNNNMLSKIDNEFNVVILV
                     GDSVGELSFVGKGAGRGATGSAVYADIIDIIDNRSSNIKSFSKGKLDLSGLIEDECSA
                     VVRFGGYNNKDGILECLDKYVDSYDIIDDEELAIFVSAKSEHEIDRVLEIVKRNNYSE
                     SAKKLLKID"
     regulatory      complement(10829..10935)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(11027..11395)
                     /locus_tag="PC465_000658"
     CDS             complement(11027..11395)
                     /locus_tag="PC465_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HDF2647989.1"
                     /translation="MLKGKQRAYLRSLANTLKPTTQIGKEGVTESFLEQLDGMLRTRE
                     LVKVTILENAGLDTKETANAVCEALRAEFVQAIGFKFTIYKRNIEEPKILFPGHEQAK
                     AKTKNNNVTKKGKPTKRAVR"
     gene            complement(11447..12724)
                     /gene="obgE"
                     /locus_tag="PC465_000659"
     CDS             complement(11447..12724)
                     /gene="obgE"
                     /locus_tag="PC465_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HDF2647990.1"
                     /translation="MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASI
                     IFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGL
                     VLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
                     VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIE
                     GASEGIGLGHEFLRHVERTKVLIHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRP
                     QVVVANKFDILEDESKFEKFKSELEGRGYTVFKMSAATRQGIDEVIAYVSKMLKEVED
                     VELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQK
                     AMESQGVFDRLREMGIEDGDVVKIYELEFEFYN"
     gene            complement(12835..13125)
                     /gene="rpmA"
                     /locus_tag="PC465_000660"
     CDS             complement(12835..13125)
                     /gene="rpmA"
                     /locus_tag="PC465_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HDF2647991.1"
                     /translation="MLNMNLQLLASKKGVGSSKNGRDSISKRLGVKRFDGQLVTAGSI
                     IVRQRGTKIHPGTNVGKGSDDTLFALVDGTVKFERKDKKRKKVSIYPVAIAE"
     gene            complement(13139..13456)
                     /locus_tag="PC465_000661"
     CDS             complement(13139..13456)
                     /locus_tag="PC465_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HDF2647992.1"
                     /translation="MIKVKYYYNDDFLLQGFCLKGHADFAEIGYDIVCAAVTSNAIAV
                     INSLDKLQKIEFEKVVGEEGHIECIVKDTHVKDAQLLLNHFQLAVKEIKREYPKNIKI
                     LKK"
     gene            complement(13471..13782)
                     /gene="rplU"
                     /locus_tag="PC465_000662"
     CDS             complement(13471..13782)
                     /gene="rplU"
                     /locus_tag="PC465_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HDF2647993.1"
                     /translation="MYAIVKTGGKQYKVSEGDVLFVEKLEANAGDVVTLNEVLACSKD
                     GELKLGSPVVEGASVQAKVVEQGKAKKVIVFKYKAKKDYRRKQGHRQSYTKIVVEKIN
                     A"
     gene            complement(13883..15304)
                     /locus_tag="PC465_000663"
     CDS             complement(13883..15304)
                     /locus_tag="PC465_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HDF2647994.1"
                     /translation="MKKIVIESLIGSQKTAVLEDERLTELFVEDNLNKKTVSNIYRGI
                     VKKVIPGIEACFVDIGFKKLAYLQLKKGSTIKSGQDILVQINKEEIGTKGAKLNTEIS
                     ISGRYIVYIPSNDRTTISNKITDEKERFRLKKITKAVNKENLGLIIRTEAQGCTHDEI
                     KKDIEELKLKYENILKEYKLGIGPKLLYKSLDFATKYVKDNVNDDIESIITNSYDKYS
                     ELKSILRGIDKTYVDKLCLEENRDVFDLYRIESKIEKLLNKKVWLKSGGYLIIEKTEA
                     LTVIDVNTGKFIGTGKLDETVYKTNLEAAKEIVRQLRIRDIAGIIIIDFIDMHKKKHQ
                     KEILHILEEEFNKDKRKAEVLGMTKLGLVEVARRREKESIDKYYLMSCPCCDGEQTIK
                     SVHYILDSIEKEIMRISEHTVYKNIMVEFNDFIFEQIKEYYMDIIDKIGEKYNIKISL
                     NANSTLKHNKTNVIFDKIVDNKM"
     gene            complement(15322..16023)
                     /locus_tag="PC465_000664"
     CDS             complement(15322..16023)
                     /locus_tag="PC465_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2344 domain-containing protein"
                     /protein_id="HDF2647995.1"
                     /translation="MSKIIRVKFKKEGDMIYISHLDLQRLLQRAFRRAEINLSHSQGF
                     NPHPKMSYGNALALGTESQGEYVDIEIEEDDLSVEEFLNKVSIQLPDGIDFIKAKEID
                     RQTPSLSSVIDYGEYLFNIDLKRPMTKEFVKRKVIDFMNNKEIIITKKNKKGKMVEVD
                     IRPMIRTFDVLNLEDEHITLTATIATGSKTNLNTNILIPKILEMFELDIDPLDVDILR
                     RDLYVLEDGELVTPM"
     gene            complement(16025..17869)
                     /locus_tag="PC465_000665"
     CDS             complement(16025..17869)
                     /locus_tag="PC465_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03960 family B12-binding radical SAM
                     protein"
                     /protein_id="HDF2647996.1"
                     /translation="MNKVDLKKILKKVEKPARYLGNEINSIHKDTSNSELIRYAHCFP
                     DLYEVGMSHLGSHILYDVINKDEDVFCERVYSPAVDMENIMREKSIPLFALESREPIT
                     NFDFVTFTLQYELSYTNILNILDLANIPILKEERTLEDPFIMVGGPCAYNSEPLADFV
                     DVVILGEGEEVNLEVVNEYKEWKKNKTTREDFLYKISSIEGVYIPSFYDVKYNEDGTV
                     QSVTPNREGITKNPTKRIIKDVETVDYPEKLIVPYIDTVHDRIVLELFRGCTRGCRFC
                     QAGMIYRPIREKSVKRLKEILDKLVKNTGYDEISLSSLSTSDYSKLSELTDYLVDEYA
                     SNNIGISLPSLRLDNFSMEIADKIQQVRKSGLTFAPEAGTQRLRDVINKGVTEEDLEN
                     ATERAFEMGWNSVKLYFMIGLPTETYEDLDGIAKLAYKVIDIYRKVNGGKLKRSFSVT
                     VSTSTFVPKPFTPFQWHGQDTTEEVINKQRHLVNKLRNNNIKYNYHDSKTSLMEAVVA
                     RGDRRIGKVIYDAFRLGAKFDGWAEHFNLDIWKEAMEKNNLSIDFYAHRNRNYEEVFP
                     WDHIDVGISKKFLIREDENAKKEKITSDCRHNCNGCGINIHDIGRGLC"
     gene            18188..19381
                     /locus_tag="PC465_000666"
     CDS             18188..19381
                     /locus_tag="PC465_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HDF2647997.1"
                     /translation="MSKVFEVKKDIYFTGVVDEGLKVFDIIMETEFGTTYNSYLIKDE
                     KTVLFDTVKANFKDEFLSNLSEVTDIAKIDYVVIHHTEPDHAGSLKYLLDINPNIEVY
                     CTKAAKLYLDGQINRPFNCHVIKDGEILNIGKRNLRFITAPFLHWVDTMFTYIEEDKT
                     LLTCDAFGCHFASVDAEVVNSEDYLKSAKHYYDCIVKPFAKHVLSAVDKVVGLNIEFD
                     TILTSHGPMLTKDPMAAVKRYVEWSTEAVNTTNQNQVSIFYLSAYSNTLEMAKKIKEG
                     LDKEGAKAELYDLEDMTLTEMHDTLVVSKVILLGSPTINKTMVKPMWDLFSVIDPMAN
                     QGKIAGVFGSFGWSGEGITMAETLLKSMSFKMPVESLKKKFFPSEETLKECMAFGAEF
                     AKLVK"
     gene            complement(19593..20414)
                     /locus_tag="PC465_000667"
                     /pseudo
     CDS             complement(19593..20414)
                     /locus_tag="PC465_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428476.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(20544..21335)
                     /locus_tag="PC465_000668"
     CDS             complement(20544..21335)
                     /locus_tag="PC465_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2647998.1"
                     /translation="MKLIDEYLDKLYKKCDNKSTIELKQEMRCHLIESANEFKLEGLD
                     EEEACKKAIERFDDGDEMQYELCNIIKELSLSLDRHKSIVMGFKKVLGYISIIAFLIS
                     GFMWYYNNSLQHNMYNLGKELDGEIKQLAERHDMTKIGEYKLELEKILDKDKYSKVKA
                     LRLYVIDMKDGNTNLSSSGLNANMVYEREADYNNISNFIQHLGYNGKDFLDKNGNIVN
                     PDIFLEYFFYFESEMLIPVAFAFGLLCIIAYFILRFKISLIKNNN"
     gene            complement(21339..21668)
                     /locus_tag="PC465_000669"
     CDS             complement(21339..21668)
                     /locus_tag="PC465_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2647999.1"
                     /translation="MQLNKEVLKGYIDILIVSILEKKDCYGYEIAKQVRERSEFELKE
                     GTMYLALKRMESKNLIKSYYSNEQSSGGRRKYYNLTNEGKDFLEIKKQEWRFIKKVMN
                     QFLGEVD"
     gene            complement(22152..22565)
                     /locus_tag="PC465_000670"
     CDS             complement(22152..22565)
                     /locus_tag="PC465_000670"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HDF2648000.1"
                     /translation="MNIALVAHDQMKNTMVGFCIGYESILKKYGLYATGTTGKRIMDE
                     TELNINRLASGPLGGDQQIGSLIVTQEIDLVIFLRDPLTSQAHETDIQALIRLCDVYH
                     VPIATNLASAEIFIKALDRGELSWREVRKSKSQRI"
     gene            complement(22606..23736)
                     /gene="rodA"
                     /locus_tag="PC465_000671"
     CDS             complement(22606..23736)
                     /gene="rodA"
                     /locus_tag="PC465_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HDF2648001.1"
                     /translation="MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHAN
                     STGSYNQLIKQGLAFVLGIGMIIVILFFDYNLLGRYYKALYIISLILLAIVLLPGIGT
                     VKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFI
                     GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVR
                     IEAFLNPEDVTLKGNYQVMQSLIAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVV
                     GEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTV
                     ALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF"
     gene            complement(23821..24105)
                     /gene="minE"
                     /locus_tag="PC465_000672"
     CDS             complement(23821..24105)
                     /gene="minE"
                     /locus_tag="PC465_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HDF2648002.1"
                     /translation="MLDLFRVFSNEAKTSKSVAKERLKLVLVHDRVDCSPQLLEMIKT
                     DILKVIANYAEIEDDGLEIKMSKCRGEHDDKPVSALVANIPLKNIKDRCM"
     gene            complement(24123..24920)
                     /gene="minD"
                     /locus_tag="PC465_000673"
     CDS             complement(24123..24920)
                     /gene="minD"
                     /locus_tag="PC465_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HDF2648003.1"
                     /translation="MSEVIVITSGKGGVGKTTTAANLGTALSLENKKTVVVDADIGLR
                     NLDVVMGLENRIVYDIVDVVEGTCRLKQALIKDKRFDNLYLLPAAQTRDKNAVSVEQM
                     IDLCEKLKESFEYIIIDCPAGIEQGFKNAVAGADRAIVVTNPEISAVRDADRIIGLLE
                     ANEIKEIRLVINRIRNDMVKRGDMMDKQDIIEILAIDLLGLVPDDESIIISTNKGEPA
                     ILDSKSLAGQAYKNIAKRILNEEVPLLDLEVEDGFFGRLKKMFSMAK"
     gene            complement(24944..25627)
                     /locus_tag="PC465_000674"
     CDS             complement(24944..25627)
                     /locus_tag="PC465_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HDF2648004.1"
                     /translation="MSLREICSQELVEFKGNKRGIIVNIKREAPFEEIQEKIINKLEA
                     YVGFFNGAKISKINSDCLTDMEILELKEGITSRFDVEFVEDQKIEENSNFPTKYVNTL
                     RSGENIEFEGDVVILNDMKPGSKVLSKSNTVVMGDINAGAKVVAGGNVFVMGKIEGFV
                     HAGAEGNEFAYVVAGNLNPKILQIADNIAEAPDDEENYESESEISPEIAFVSNGRIVI
                     ESYLSKLDK"
     gene            complement(25725..28703)
                     /locus_tag="PC465_000675"
     CDS             complement(25725..28703)
                     /locus_tag="PC465_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HDF2648005.1"
                     /translation="MEENKQVDRLKIIKIVMGVIFLAILVKIIYMTTFKYEYYNELAE
                     NKTYKKLAIEAPRGEIKDRYGRLLAGNKNLFTVQVSGNDINKKDANKHSRANEISLKL
                     INLLERNGEEYVDEFPIYVENGKYYYTYDRDIREYKSENGIPNDYNAKESFYYLVDKL
                     ISAGILSQEDKRLDATRLQAKLNENGYYPPILVSKWMFTAERDKRDWLASYKIKETKL
                     SAKEAFEKVRNSDALEIDKSLSDEDARKIMVVRDLIKSKGYSQYNPVTIAKDVGETTI
                     AQIEESAMDLVGVSIAVEPVRYYPNGSLASHMLGYVGKMPSTQIESYLQKGYETGDMV
                     GLAGVEKSNESRLRGTDGYKMVKVDALGRISKEIESKKPKSGDTVYLTLDKDLQEVSD
                     NALKQIIEVASKGGTFKSKFGDKPISAYAGKAQSAALIAIDVKNGEVLASSSYPNYDP
                     NKFAKGISTEDYKALQPKNPNDLLAGSPLLNLVTQGEFQPGSSFKMLTSMAALENGLD
                     PNFTINDPGVIMLGKKSFGDYVWNHGRGNHGMTNLYKAIQESCNIYMATIGTGKTWPD
                     GKSIGIDMNANKILEYAKLFGLDQNTGLQDEVEERAGKVPSAEDKLKSTQALLKSNLE
                     REMANDFVDITREKNPKEYEKRINEIVSWAAEKKTPGRVETMNRLKKLDVKEDRIEEV
                     ADLAVFSYFNFTKWSTADTFNLAIGQGENAYTPAQISRYVAAIANGGNLVELSVVDRA
                     VSSDYSSVKINDQKKVEKIPFKNPDNLKELTKGMKLVVRQGTAKSAFADLPIDVAAKT
                     GTAEKSGKIPTDNEYEYLKSHMSSYNVNLNDAIKLADKMKAEKEKELSLAKEKEIKKK
                     LENKDLKDEERKKLEEELEDGVKVRLEDTDKVNSSYLRKAIKELNPKITDDQIDRFKQ
                     DYGSFTWTVAFAPADDPEIAVVCVIPQGDSSVFSLLPTREVIGTYMGLEPTNSKNDNK
                     TNDVNNSSDENINFESQINR"
     gene            complement(28715..29203)
                     /gene="mreD"
                     /locus_tag="PC465_000676"
     CDS             complement(28715..29203)
                     /gene="mreD"
                     /locus_tag="PC465_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HDF2648006.1"
                     /translation="MKKVLLCLLGIVLMTIENSITNYIDIFGISFNLVLIYVTIISLY
                     LDELEGGIIAAIIGLIKDITVGGIFGVNALILFIIAYAIGYMRDQLYKGSYIITFVLI
                     FIGSLIDSIVNIGTSSIIYQSYNISTLFVKGLLVAPIVNSLIGLVIYRLSKRAVLKLK
                     ED"
     gene            complement(29218..30111)
                     /gene="mreC"
                     /locus_tag="PC465_000677"
     CDS             complement(29218..30111)
                     /gene="mreC"
                     /locus_tag="PC465_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HDF2648007.1"
                     /translation="MALRFDKNKNEKKRINVKVIATGVVAITLIGIVGISIGKFSSGS
                     PVNLGVASDAITSVGKGINDGFSFIKNGFKDVANFKDNSKKVKKLEEENEKLKKNMIA
                     LNAKLDKTESLEELKKTLNFVQEEYKATSISASVVGKNDGNWYESFVIGAGKNSGVKK
                     ESIVMNGSGLVGIVYEVSNNYSKAISLLDSKASVSFKLAKDANAKGTITQNTTLDNKD
                     SYNSKGYLQGYMFDSSYNVIQGDIITTSGLGFFPDGIPIGEVEKVVDDKDKSLKYVVV
                     KPYVDFKNINDVVVIEPRNIG"
     gene            complement(30121..31131)
                     /locus_tag="PC465_000678"
     CDS             complement(30121..31131)
                     /locus_tag="PC465_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HDF2648008.1"
                     /translation="MTKDMGIDLGTANTLVYIKGQGIVVREPSVVAIRDDSKEVLAVG
                     EEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQKAADKKGVVSPRIAICVP
                     FGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVEEPEGNMVVDIGGGTSEI
                     AVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERTAENVKINIGSTFKDDEE
                     INMQIRGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIKSTLERTPPELASDIMEN
                     GIMLTGGGALLRGLDKLITQETGMSVQIAETPLDCVALGTGKSVEDQEIFEKVLMMNT
                     KN"
     gene            complement(31252..31911)
                     /gene="radC"
                     /locus_tag="PC465_000679"
     CDS             complement(31252..31911)
                     /gene="radC"
                     /locus_tag="PC465_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HDF2648009.1"
                     /translation="MAPEERPREKMLAKGVKSLSNAELLAILLRTGNKNKNAIELANY
                     IINRDIQGIRHLEDMTIEELCNIDGIGLSKSTQIKAALELGSRVASFKPIKYKIRNPW
                     DIQRYYMDSLRYLKKEVFKAVLLNTKNEIISDVDVSIGTLSSSLVHPREVFKEAIRRS
                     ASKIIVMHNHPSGSVEPSREDKNITSRLIKCGEIIGIEIIDHIIIGDGLYFSFKENMI
                     I"
     gene            complement(31956..32540)
                     /gene="maf"
                     /locus_tag="PC465_000680"
     CDS             complement(31956..32540)
                     /gene="maf"
                     /locus_tag="PC465_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HDF2648010.1"
                     /translation="MNIILASASPRRKEILENTNVRFDIIKNEIDEIILEGETPKHLV
                     MRLAFEKSMSVASEHNEDVVIGADTVVVLDNAILGKPKDESCARDMLKRLSGREHQVI
                     TGISLINLCEDKKVIDYVISNVKFKTLSEQDIEDYLKTNESFDKAGAYGIQGYGALLV
                     EEIRGDYFNIVGLPISRLGDLLKKYFSINLFYGV"
     gene            complement(32785..33756)
                     /locus_tag="PC465_000681"
     CDS             complement(32785..33756)
                     /locus_tag="PC465_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HDF2648011.1"
                     /translation="MVILTAVLVLGIMGLIFGIVLDFASKKFAVEVDERVEAILGVLP
                     GANCGGCGFPGCGGLANAIVEGNAPVNGCPVGGADVGAKVGEIMGISAEAGEKQVAKV
                     ICKGTCSSAKDKYEYEGISDCRAANVLNSGAKMCKFGCLGLGTCKDACKFDAISIVDG
                     IAVIDEEKCVNCGKCKEVCPKGIIITKPESQEVVVECNSKEFGKAVKEKCTAGCIGCG
                     MCVKACKFDAIIFEDKIAKIDPNKCVGCMQCVAKCPTKVISGDITKKKKVTIDQELCV
                     GCTVCKKQCKFDAIEGELKEKHKVDADKCVGCHLCMEKCPKKAIKIL"
     gene            complement(33772..34347)
                     /gene="rsxA"
                     /locus_tag="PC465_000682"
     CDS             complement(33772..34347)
                     /gene="rsxA"
                     /locus_tag="PC465_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HDF2648012.1"
                     /translation="MNLILLFLSIVLVNNVITSQFLGICPFLGVSKKVDTAVGMGVAV
                     TFVLTLASIITYFIQILLVKTGTGFLQTIAFILVIASIVQFVEMVIQKMSPSLYQALG
                     VYLPLITTNCAVLGIALVNVQKSYNLVETIINGFGAGAGFTLAIVIFAGIRERLELAD
                     IPEAFKGFPITLISAGLMSIAFLGFTGLIKL"
     gene            complement(34362..34955)
                     /locus_tag="PC465_000683"
     CDS             complement(34362..34955)
                     /locus_tag="PC465_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit E"
                     /protein_id="HDF2648013.1"
                     /translation="MNLAKVFKNGLIDENPTFVQVIGMCPTLAVTTSAINGIGMGLST
                     AAVLICANLVISLIRKITPDKIRIPIFIVVIATFVTIVGMLLKAYVPALDKALGIYIP
                     LIVVNCLILARAESFAFKTGAMPSIVDGVGQGLGFTVALTIIGAVRELLGNGSLFGMT
                     LFGASFQPVLIFILPPGAFLTLGFLFAGFNKLRSKKA"
     gene            complement(34968..35537)
                     /locus_tag="PC465_000684"
     CDS             complement(34968..35537)
                     /locus_tag="PC465_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HDF2648014.1"
                     /translation="MNSMVRLGGTLLAISAIAALALGATNQVTAPVIEQRNIQANNEL
                     RKAVLPEAKEFKEMKEDTYKGLGDGLIAEVYEGLDGSEVVGYTLKAKPSGYGGEIEVM
                     VGISSEGQVTGVDIGNMSETAGLGAKAKDDAFKGQYKGKTAEPLEVAKGSTTADNQIL
                     AISGATITSTAVTTGVNAAIDVFNSALNK"
     gene            complement(35537..36514)
                     /locus_tag="PC465_000685"
     CDS             complement(35537..36514)
                     /locus_tag="PC465_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HDF2648015.1"
                     /translation="MENKLIVSSSPHVRSNEDTSYIMKQVIIALLPAAVAGVYFFRLN
                     ALSAMFFCILGTVGTEFLYQKFTKQKSTIGDFSAVVTGLLLAFNVPASLPWWMCLVGG
                     IFAILVVKMVFGGIGCNFVNPALAARAFLLASFPVAMTAWTQPGVNWIGKNLDAVTTA
                     TPLSFLKNGAAGLADLSSNGISLADMMIGNIGGCIGETSAILLLLGGVYLMYKGIINY
                     VIPVFYIATVFILTFLLGGFNITFAIYQLFAGGLMLGGFFMLTDYTTSPMTKKGQIIY
                     AVLAGLITTVIRMYGGYPEGVSYSILLVNCLAPLIDKFVRNRVFGEVAK"
     gene            complement(36537..37874)
                     /gene="rsxC"
                     /locus_tag="PC465_000686"
     CDS             complement(36537..37874)
                     /gene="rsxC"
                     /locus_tag="PC465_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HDF2648016.1"
                     /translation="MKLLTFKGGIHPPYRKEYSNTKALEKAQAPKIVYIPLQQHIGAP
                     AKPIVEVGDEVKFGQKIGEQQGFVSCNVHSSVSGKVIAIEQHEVPGGSAQCVVIENDF
                     KEELHESVQPKGQLEDLSKEDIVGIIKEAGIVGMGGATFPNHVKVSPPPDSKAEVVIL
                     NGAECEPYLTADHRLMVENPEDVVFGLRALMKVLDVKKGFIGIETNKPDAIEAIQNVA
                     KDYSEIEVVGLQVKYPQGAEKQLIYACTGKEVPSGGLPIAAGAVVDNVATAAQIAKSI
                     KTGMPLVERITTITGSCIKEPKNLITKVGTLVSEIIEQCGGFKEDKKIGKVIMGGPMM
                     GIAQYTTEIATNKGSSGILCLDEEESRTPDIQNCLRCGRCTDVCPSFLQPLFISAYSL
                     KDDYDTAEYHRAMDCIECGSCSFICPARRPLLQSIRSAKREIGAKRRKQAAQK"
     gene            complement(38090..39034)
                     /locus_tag="PC465_000687"
     CDS             complement(38090..39034)
                     /locus_tag="PC465_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648017.1"
                     /translation="MNRRKTIYRGFNNNRHKIDLRKYVITIACLCLIGYYSYTKIKDS
                     KILEYVSAKIPFLNNSSDITYKDISDELNSIKKGKKSKSQTNSDDKQETNPEKAVNNT
                     KEPEEVKLATIEGWDMYTIQVAAIDNNDDLKKIQTSLVNNDIPFSVMEKDGVKKIQTY
                     SSFDENDVRKQISSVRKVFPDAFLSHLDAPMLSLEYTSNYAYIESISKELNKLITNFK
                     EESSFWSNAENNVDMEKYNTILTNRKAISQNISKEAEKIDYSEMRLFKDNLIEYVKNV
                     NEKIDTASKAANEEKYSVSKSLLLSSMQEYSMFINSIK"
     gene            complement(39145..40419)
                     /locus_tag="PC465_000688"
     CDS             complement(39145..40419)
                     /locus_tag="PC465_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF2648018.1"
                     /translation="MKKAIAALGIGAVAVSVSSINASALEKGTVTASALNIRSGPSSD
                     CDKVAKLYKGKTVEILEKSNGWYKVRVSSSVVGWGSAKYISTSGSSEGTSSQNNSTSS
                     GTTISGNGKVNVSSRLNVRSGAGTNYSLVGKANNGDVVKLLEQSNGWYKIKLSNGVTG
                     WASSQYISKTSEDVGTNNSSNSNSTNNSDKKPSSEESIEGKNGKVTSAVSLNVRSGPG
                     TSYSIIGKLNGGDVVELKAKSNGWYKVKLSSGTIGWVSASYISETNEDTKEKPNSSSN
                     QNSQSNSNSKPSFTGNSDKSTAKGSTIVDFAYTLIGIPYQWGASGPDKFDCSGFTQYV
                     FKHSVGVSIPRVSREQANFGSAISMGNYAPGDLVYFDTDGDGTTNHVGIYVGNSKFIH
                     CSGTQTNPNKVKVDNLTSSYWSKVLLGARRFV"
     gene            complement(40551..40922)
                     /locus_tag="PC465_000689"
     CDS             complement(40551..40922)
                     /locus_tag="PC465_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2648019.1"
                     /translation="MKFNFCHNNFNVTNLEKSLDFYKKALGLKEVKRKEAEDGSFILV
                     YLGDGITSHTLELTWLRDWDRPYNLGDNEFHLALEVEEFDEAKKLHKDLDCICFENES
                     MGIYFIADPDNYWIEILPKNH"
     gene            complement(41150..41749)
                     /locus_tag="PC465_000690"
     CDS             complement(41150..41749)
                     /locus_tag="PC465_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648020.1"
                     /translation="MESRGYKEDLKKMILDMAHKELESYVSQKGAKKYFEGNLDKIIN
                     NNIKKFNQSIGLNRVYLKMLKKCAYQESVTSISRTIKKEALFKSKKELFAFSEYLKLD
                     INKRLSYNQILRKISRYIYYNRSSYAQKYVVFKRGDEEYLLEPEKIKDELISSYRSKT
                     REDMRSIAKLLDIEVEDDYNAEDIRKKVINYIIKEKLKS"
     gene            complement(41950..42162)
                     /locus_tag="PC465_000691"
     CDS             complement(41950..42162)
                     /locus_tag="PC465_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HDF2648021.1"
                     /translation="MKKKLLVEGMSCGHCVNHLKTALTEDIDGIEVLDVDLENKCASV
                     DMKDDVSIEKLKEVIAELGFELKGIE"
     gene            complement(42235..43950)
                     /locus_tag="PC465_000692"
     CDS             complement(42235..43950)
                     /locus_tag="PC465_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2648022.1"
                     /translation="MKRIKVLTVVLAITLMVAGCSNTKTKQSSSDSSLQSQSSIDAKY
                     INLTMVTPKTINPITNTDKSVGYIMNLVYDSLFTIDENYNVIPQLVKEYNIAQDGMSI
                     DIKLKDAKWHDGKNVTSNDVNYTIGLIQKSADSPYNEFTKNIASVNIKSDKDFTIKFK
                     ARYAFSIDSLIFPIVSQNHLDSKDVNDKNNNMIGNGKYKIESYTEREGMVLSVNKDYY
                     EEVPKTMKNIKVGMVPNEDARTSMVMALDSDITNVTLNDLSKFQEKEFNITKYQGRDY
                     ECVLFNYNNPFFKDVNFRKAIAHSIDKDRIISEGYMDDATPVNFPLNSKSKYYNSEMK
                     DLEFNKDKAIECLAKVEYANVNSVNQNDNKVKNQKKSAKKNSKKLTPEEEAKAKKAEE
                     DRIKKEAEEKKNREKEEVKKSLSEMNLKIIVNRDNSERIKTANIINENLKAIGINSTV
                     NQLSDKDMENALNSKNYDLALVGWKLSIIPDASSIIASSGYTDDKLNGYMSALTSSTS
                     EIETKKAYKDVQTYIKDNATFISLAVRNNYIVSNSRLKGKITPNDFDVYEGISNLDIK
                     SNESN"
     gene            complement(43950..44504)
                     /locus_tag="PC465_000693"
     CDS             complement(43950..44504)
                     /locus_tag="PC465_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HDF2648023.1"
                     /translation="MNSKKVLILSIFIILFGALLMESKVIHKFLYPKKYSEYVEKYSK
                     EFNLDENIVYSVIKAESKFNSSAVSKKEAKGLMQILDITRDWGAEELNLKNVDIFDPE
                     TNIRLGCWYLSKLYKEFGKLDLVIAAYNGGSGNVKKWLENNEYSKDGENLHDIPFKQT
                     SKYVEKVKNNYEHYNKIYGKKGKN"
     gene            complement(44497..45099)
                     /locus_tag="PC465_000694"
     CDS             complement(44497..45099)
                     /locus_tag="PC465_000694"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HDF2648024.1"
                     /translation="MLILGLTGGIGCGKSSLSNIFRNLNIPIVDADIISRKIFEDKLL
                     LEKIFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLKELNNLTHPRIREKIISEIEKLR
                     KKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSEQEALSRINSQ
                     MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE"
     gene            complement(45108..47756)
                     /gene="polA"
                     /locus_tag="PC465_000695"
     CDS             complement(45108..47756)
                     /gene="polA"
                     /locus_tag="PC465_000695"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HDF2648025.1"
                     /translation="MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFK
                     MIDIYKPTHISVAFDRKAPTFRHLEYKEYKAGRKGMPDELAEQLQPLKDLLDKFRINR
                     LEIDGYEADDIIGTVSKKAEENGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY
                     NFNSVIEKYEMTPTQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENT
                     DKLKGSVKKKIEENKEIAIQSKRLATIIRDVPIEVDLDSMIFGDYDKDELLDKFRYFG
                     FTSLLSRLVDLVDSDDTEHVEEKIEILKLKDIEKFIDEVNKKGQVILKTVRGQGNILE
                     KNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLEN
                     MYFDITIAEYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDL
                     AEYMGQIICTVKETVPMMERSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILD
                     ELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTGYSTNAD
                     VLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRIS
                     STEPNLQNIPIKMEMGRKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFK
                     HHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKE
                     YIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAM
                     NAPIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKE
                     EMENAVNMDVHLDVDLNVGSSWYETK"
     gene            47908..47995
                     /locus_tag="PC465_000696"
     tRNA            47908..47995
                     /locus_tag="PC465_000696"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47942..47944,aa:Leu,seq:caa)
     gene            complement(48182..48625)
                     /locus_tag="PC465_000697"
     CDS             complement(48182..48625)
                     /locus_tag="PC465_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648026.1"
                     /translation="MKKNMLYVGIIYFICGILLVLLATFTEFSFEAFIWGLSGAALGP
                     GVCMILQYMYWSKPERAVDYEEKIKNQRIEMNDERRIMLRDKAGRITNQIMCYVLVIL
                     IFIVSILSVFSVMVISKWVLVVLGLLILFQFICSVVVYNKLDKRL"
     gene            complement(48628..48825)
                     /locus_tag="PC465_000698"
     CDS             complement(48628..48825)
                     /locus_tag="PC465_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004631111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2648027.1"
                     /translation="MKNRLEEIRKERGIKQEELASILQVSRQTIGSLENGRYNPSIIL
                     AFKIARYFDMSIEEIFIYEEE"
     gene            complement(49017..49883)
                     /locus_tag="PC465_000699"
     CDS             complement(49017..49883)
                     /locus_tag="PC465_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2648028.1"
                     /translation="MEWINKLNQAITYIEENLESGVDYAEAAKIACCSTFHFQRMFSY
                     IAEVPLSEYIRRRRMTKAAFELQNSNIKILELSEKYGYDSPTSFNRAFQNIHNISPSA
                     ARAKGVVLKAYPKMTLSIYVKGNIEMQYRIVEKKGFRIVGIKESMNMIVEECFEKVPK
                     LWAKCIKNGTIDKLSELINNEPCGLLGVSVCTNSKGLDYYIAAPTDKPVLEDTHEYLI
                     PSGTWAVFECVSPMPNALAIQELQKRIITEWLPSSGYVYANLPDIELYPNGDINAPDY
                     TTEVWIPIQKPN"
     gene            complement(50109..50978)
                     /locus_tag="PC465_000700"
     CDS             complement(50109..50978)
                     /locus_tag="PC465_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2648029.1"
                     /translation="MDYKTIILNRKSVREYKNTDIKEEYLSEIKKYSESCKKLVPEID
                     VDVRIMNRSEVFNNLDKVAGYKGNMIDSPSYIIILSDIKDNYIENSGYIGESIIFKVT
                     ELGIGSCWVTFEDGKKVKEKLGINSDKEVTGIIAIGYGENVSNAKVLNATKTGQNYSK
                     SDMQVVTDKGSTRLGVEDVVYMNEWGNVASIEILEERALLDAFHYARLAPSTLNRQPW
                     RFIVDGGTVVLAVRKDGHTNLYEEKIDIGIVMLYFATIISATMFDLKWNLGTPDKDYK
                     VPEDYKIVGYCNI"
     gene            complement(51484..51705)
                     /locus_tag="PC465_000701"
     CDS             complement(51484..51705)
                     /locus_tag="PC465_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648030.1"
                     /translation="MNVNNHKCPECGEHSKKFEIVEENEDCVIFECYTCGTISILKYC
                     ENCKEFVFVNIPNNVETYEYCCGKCNNKI"
     gene            complement(52206..53186)
                     /locus_tag="PC465_000702"
     CDS             complement(52206..53186)
                     /locus_tag="PC465_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648031.1"
                     /translation="MGDTSRFYESVKNKYPKLKDGTRVHLWPKENIIIGPIYDEEDGY
                     KKSIGNVDSLSWKQIVILAECDGKNTTDDIINILSNRYRNIHNMKEKVMEFFMFYENV
                     YLTFEDDIQTLSSVFEITGNKSYITPLYFTIEIDGDNNTNDYFSEITSLLNCMYEKGC
                     RFIEVIGEDILKNKSMREIFQYMLDHFDLIVVTKDSFTIDRSLIKELDNYRHKVIWKV
                     YSKNDDTRIKLKEDIKITSLIKRGHTVVRGDREKAIKIEDMRFKDTKERFSKYGAEWS
                     HLYISSDGSVKSYSFQKDKRIYLGNIFNNSVEEIFLEMQNKIDKLEIVYQ"
     gene            complement(53350..54222)
                     /locus_tag="PC465_000703"
     CDS             complement(53350..54222)
                     /locus_tag="PC465_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2648032.1"
                     /translation="MIIKVSMTVLVLILLYILYKYETQHIETTEYTIFNKKIPKEFDN
                     FKIVQVSDLHNKVFDKNNKVLIDKIESLNPDVIFITGDLVDGENKNFQVALDLIDNLV
                     EKYEVYHIIGNHEQKSLIKKYKHLYKDYFKELYSKKIINMENESVRIYRGNSHLNLYG
                     LIIPLECYPYLFANNKKLELSDNFVEDNLGKVNENEYNILLAHTPFFFEKYAKWGADL
                     VLAGHVHGGIIRIPFVGGVLSPNREFFPKYDWGKYEKDNSTMILNKGLGGSKVLIRLN
                     CKPEIVKITLKYEK"
     gene            complement(54386..54937)
                     /locus_tag="PC465_000704"
     CDS             complement(54386..54937)
                     /locus_tag="PC465_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2648033.1"
                     /translation="MDNKFPNVGENLRLLRQEMGISLDKASKMTGVSKAMLGQIERGE
                     SSPTVSTLWKISSGFKINFTTLLNENTNTYEVIKKEEVEPIVEQKGNMKLYPIYPFSP
                     QRRFELFIIELEENCTHVSSTHSHVLEEYVLVIEGKLDLNVDGKTYILESGHSIRFDG
                     TLEHIYKNLNKGKTIFHNIEVYR"
     gene            complement(54957..55859)
                     /locus_tag="PC465_000705"
     CDS             complement(54957..55859)
                     /locus_tag="PC465_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HDF2648034.1"
                     /translation="MSKKGRVVKVQHFSVNDGDGIRTTIFLEGCKLKCKWCSNPDSWS
                     NIVKLGVMKDKCVSCNRCIDVCPQNISSLFDRTQINNKCDLCGECIKVCLKDAICIMT
                     EEMSVEEIVEEVEKDFIFFFESNGGITFSGGEPTLQIDFLRELVDIFYDKGINIAIET
                     CGYFDWNKVNDVFEKIDHIFVDIKSMDDNIHKEYTGVSNKIILDNICRLSKLNKSMVI
                     RVPIIYGVNDSEENIRNTALFVKQNVPGGKMELLPYHKFGIDKYKALGLEDYIYEFDE
                     ICNNHMLKLKEIVELTGVKIIEYK"
     gene            complement(55874..58246)
                     /locus_tag="PC465_000706"
     CDS             complement(55874..58246)
                     /locus_tag="PC465_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase/glycerol dehydratase
                     family glycyl radical enzyme"
                     /protein_id="HDF2648035.1"
                     /translation="MSQTNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIR
                     RAKAFLETCKELPIKIFENELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDP
                     YVISKEQIEFIRKEIFPYWKGKSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGE
                     VTPDYQDILFVKGYKGIKEDADKKIKELDISVSENIEKIDFYKSVSIVAQGIMTLAQR
                     YSNLAKEMSKQETDEKRKLELIKISEICMNVPANPPTNFYEAIQFVWFVQLGGILSEN
                     PLALNLGRFDQYMYPYYENDAREGKITESEAQELIEALWIKLSEWVWTISANTANYFA
                     GYNQFQNLTVGGKKRNGTDGTNDISYMCLKATESVKTHQPGLSVRVSQGAPDNFVMAV
                     AKLVKQGTGFPAIHSDSAGAQMLLQDGYDAEDARDWSNCGCVVPHFRKTGQWTSAVNI
                     NFAAALEYAMNEGKSRLTGEKMGLDTKNITEFTSFEELKDEFLKQLAYLVKSSVIGTT
                     VAQQIHKEMVPRPFLSTCVDGCLDKGVDLSKGGAKYNIGPVLTGIGLGVVSNSLAAIK
                     KLVFEDKVTTLEELTKALNNDWEGYEELRKLALDVPKYGNDNDYVDSLAIEVSDFYYT
                     ETRKYKDIFGSKFNSAFMGISNYVPTGKIVGATPCGRKATKPLTEGVSPFVGTDTTSP
                     LAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLRNLTSMIKSYFALGGFHVQFNT
                     ISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLSREMQDAIIARNSHSNF"
     gene            complement(58467..59156)
                     /locus_tag="PC465_000707"
     CDS             complement(58467..59156)
                     /locus_tag="PC465_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648036.1"
                     /translation="MKVKRNINRVAIIVALNLSLALMVGCMSPVSDKNLSSSEQISKD
                     SLKEQVEDKKDESIELFNNYSQKINDAKGREEVKKDLSQRFSKAIIDSGYSITNSKSD
                     GSFVVSINGAEKPPEKNIRSLFYSMSEDDKEGKVTIDILCAKEYPEDDKLSESDKYIK
                     FIYNLFKSLTNTNLTEKEIFSMVEEDFNKGVGVVELPYMKDIHVEVNKVKQSTKVLKL
                     SLVYKFDISNH"
     gene            complement(59399..60778)
                     /locus_tag="PC465_000708"
     CDS             complement(59399..60778)
                     /locus_tag="PC465_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2648037.1"
                     /translation="MLNFMTELLVVLSIFIQFSIMNGVLIYKKDSKKNEKIVFYIVLF
                     LIYIIIQISRLFNGGNYFSNINYLFYILAFIAWGGYYNYFYKMGYIKYSIFFYLFSVY
                     YKCLDAVIYRILFFAITGNVISSKESLLVPHLESIKIQIYSNLIIILIYLIFSFFRKS
                     IKLISQDKRNYVYLLFALLVNTMNMLVNYVLKKLERFGSLHSEGYYFDNFVNPKLVGA
                     SSIFLILLFKEIIKENRLKSQAELIKNKLDMQYAHYLSIQESHMRVKKLYHDINNHIY
                     CIDNLRNNSKEINEYVNNLKDEIKTFKYIYNTGNMILDIIINEKSEICLKKGIKFTCS
                     INFSKVNFVKPIDVSSIFSNILDNAIEACDKIVDENVNKYIRIKGTITRSFFVLKCEN
                     SKLNQLTFNKNILLTNKMDKFVHGIGIQSIKSSLQKYNGELLFENSIDKFILNIYIPL
                     DQDTDSWGD"
     gene            complement(60772..61485)
                     /gene="rgbR"
                     /locus_tag="PC465_000709"
     CDS             complement(60772..61485)
                     /gene="rgbR"
                     /locus_tag="PC465_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgbR"
                     /protein_id="HDF2648038.1"
                     /translation="MIKIAVCEDEKETQLLIEDYLENILKDISIEYEIQKYISGEELL
                     ESNLKDIDILLLDIKMEKLNGMDTARKIREVDNEMEIIFVTSLIDYVQEGYEVRAYRY
                     LLKPIELEELKKHVLTCIKDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIH
                     TINKNFDIKYSLGKIEKELNPYKFIRCHKSFIVNLRYVENIKPNTAILESGEEVPISR
                     YRYKEVKEKFLKFLGDTIC"
     gene            complement(61735..62295)
                     /locus_tag="PC465_000710"
     CDS             complement(61735..62295)
                     /locus_tag="PC465_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HDF2648039.1"
                     /translation="MSAMEKKIKFKFDWYSSPDKIEKWLEDIEAKGYNLYKINKFGGI
                     FYFHKGSPRKIKYTVDYYYDVENNYFDEHKSNGWNLVFRSIGSFMGTSAWYIWSKEYK
                     DIPPKLYSDSDKTNKVKSILFMNMFIFFMLVVIFIYLLNIEIRNLYSGYGASVTAIVL
                     QIILLILYAVQLYRRLMYYLRLKKFK"
     gene            complement(62391..63194)
                     /gene="zupT"
                     /locus_tag="PC465_000711"
     CDS             complement(62391..63194)
                     /gene="zupT"
                     /locus_tag="PC465_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HDF2648040.1"
                     /translation="MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSA
                     GVMIYVSMIEIFPKAQDALTKSMGEKLGSWSTVIAFFIGMAIIAVIDKLIPQEENPHE
                     IKKMENIEEKNIKKNKSLLRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
                     AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGI
                     VFAIVGGIMVFISLDELLPSAREYGEHHLSIYGLIAGMGVMAISLLLFK"
     gene            complement(63345..64508)
                     /locus_tag="PC465_000712"
     CDS             complement(63345..64508)
                     /locus_tag="PC465_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2648041.1"
                     /translation="MDIKEITKSYKDYVIKLRREFHENPEKSMEEVRTSKRVKEELDK
                     IGIPYVSAGGTGVIATIKGANPGKTVALRGDMDALQVVECTDVEYKSKNEGLMHACGH
                     DGHTSMLLGAAKVLNDIKDSINGTVKLFFQPGEEVGKGARAMIQDGAMEGVDSVFGIH
                     LWTDVESGTISVEEGPRMASADFFKITVKGRGGHGSLPHQGVDAVLASSAIVMNLQSM
                     VSREVSPLEPLVVSVGVLNSGTRFNVIASEAILEGTIRLFNPELRKQIPGILERIAKS
                     TAEAYRADAELEYGYLTPAVINDKECSKIATDAAIKLFGEDCITLFEKVTGAEDLAEF
                     MNIAPGALAFVGARNESKGACYPHHHGCFNIDEDVLEIGTALYVQYAVDFLNK"
     gene            complement(64568..65755)
                     /locus_tag="PC465_000713"
     CDS             complement(64568..65755)
                     /locus_tag="PC465_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648042.1"
                     /translation="MEAITAFCLVLVSLTIGDIVSAKTKAFVPSVFVSAIIFIVGFWT
                     FFPENIVDLAALGTPLAQLGMLLLITHMGTMMSIKELAGQWKTIVIALAGIVGICVGA
                     LALGTVVFGWDTAVIATPPLTGGLVASIMMADAATAKGLASLSVLAILMYVAQGFAGY
                     PITALMLKKEGKRLLSDFRSGKVTVNTDEEKVKDLPEQKSRFKIIPDLPEKYDTTYMI
                     ILRLGFVAWLAVQFTNLTNEVVSRYVICLIFGVIASELGIVDRKPLNKSGSFGWLMTS
                     LMAFIFAGLAKATPAMLVEMAVPLVGIIIFGVIGMGIFSIIVGKLLGESKEMAFSVSL
                     TSLYGFPPNYILTEEAVKALAETPEEKEFLMDKMLPKMLVGGFTTVTIASVVIAGIFV
                     NLI"
     gene            complement(66118..67818)
                     /locus_tag="PC465_000714"
     CDS             complement(66118..67818)
                     /locus_tag="PC465_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2648043.1"
                     /translation="MIKQFVKYYKPYKKIFTLDLIAAFLFSLCDLVYPMITRNIMDDV
                     VPNKNLRMLVVFAVALILIFIAKAGLNYFMQYWGHVIGVDMQADMRNEVFTHLQRLPN
                     TYFDNNKSGVTMSRIVNDLMDITELAHHGPEDLFISIVMLVGSFFILIDINIPLTLII
                     FAILPFIIWFAIAKKDKMNIAFMKSRVTIGDVNATLENSIAGMKVTKSFCTEKEELNK
                     FVRSNKLFRRARQDSYKVMAEYYSGMNLYMDILEWVVVIAGGYFTYIGKITLGDFAAY
                     ILYVKMFIQPMKKLINFTEQYQNGMTGFKRFIEIMEQDHQKEAKNPIELENVKGDIEI
                     ENISFTYEDKTQVLDNLSLSIKAGKTIALVGPSGGGKTTLCNLLPRFYEFDKGDIKID
                     GKSIKDVSLKSLRKNIGIVQQDVFLFTGTIRDNILCGNPNATDEEMIAAAKKARIHDF
                     VETLPDGYDTYIGERGVKLSGGQKQRISISRIFLKNPPIIILDEATSALDNVTEREIQ
                     ESLEELSKDRTNLVVAHRLTTIKNADEIIVLTDKGIEERGTHEELVNKNGVYSRLHNN
                     "
     gene            complement(68061..68336)
                     /locus_tag="PC465_000715"
     CDS             complement(68061..68336)
                     /locus_tag="PC465_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2648044.1"
                     /translation="MKKILVACGAGIATSTIVCDRVERLVKENNIQAEVEQCKIAECS
                     TKQEGADLIVSTTILPTTYDIPTIKATGYITGINTTALDKKILNALK"
     gene            complement(68455..69027)
                     /gene="mobB"
                     /locus_tag="PC465_000716"
     CDS             complement(68455..69027)
                     /gene="mobB"
                     /locus_tag="PC465_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HDF2648045.1"
                     /translation="MLLLDSFMKGHNFMYNILSVVSYSGVGKTTLIEGIIKELNKKGY
                     RVGVIKHTCHDFDMDEEGKDTYKHRKSGARKVCIISDKRVAYIEELKEKNPLYKMIQL
                     YEDMDLIIIEGYKNYRFKRLEVTRKGKYEDILSNKSDLIGIVSDIEYKLNIEQFNLND
                     YKNISKYIESCIKNEILSISNVEIKNILKE"
     gene            complement(69011..70192)
                     /locus_tag="PC465_000717"
     CDS             complement(69011..70192)
                     /locus_tag="PC465_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HDF2648046.1"
                     /translation="MIELEDAIKIIEKNVLPINRVKIVNLIDAVNKVVAEDIYSTIDS
                     PPFDRSPYDGYAYNANSENRNLKVIGTLYAGDVFNRVLNKNEAVKIMTGGKIPQGANC
                     VIKKEDVTVIGDMITLNIKLKEYDNYIFKGEDIKKGQLIINKNQNIGYDGIGVLASIG
                     ISKVTVYDDLKVGILNTGTELQDINETLENGKIYDSNRYTLYSRLLKLGIQADTICNC
                     SDDILELEKKVKNMLQSVDFLITTGGVSVGDKDLIPDVFKKIGATELFWKINIKPGGA
                     CYVGTLGEKLLFGLSGNPHAAIVVFDNVIVPVIEHLTYKKGTHHIKAIFKGEFNKLSN
                     KDRFVSGKLYTSEGKLYVELNDKKDAKARLSATLRSNCMIKIKKNETIKENQLVDVVI
                     R"
     gene            complement(70403..71137)
                     /locus_tag="PC465_000718"
     CDS             complement(70403..71137)
                     /locus_tag="PC465_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648047.1"
                     /translation="MKLKRSLVCVTILGIILVGCHKENTKEKNQVASKATQQKTMTKV
                     QNDVNEIMNKDYKYIIKNMGIPYNTFYYIKPKVLKESNTMQDINTSSYMTLVYPKYTG
                     NDELDGSALYVDINENKVVNVETNSFSSQGISVIDAESSIVIEKSDHEKSAVSLENFR
                     HIDLGEYVGVEDSRINEIVGDANYDLTAYNHEGSKVVKSYRLKEDNKILKKEVLTISI
                     VDNKIKSIKTIESDKIVKIIKGTLLE"
     gene            71499..72404
                     /locus_tag="PC465_000719"
     CDS             71499..72404
                     /locus_tag="PC465_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2648048.1"
                     /translation="MDFKQLEVFVAVAKHQSFSKAARELFLTQPTVSAHIQNLERELE
                     TVLINRSNKVITLTKSGEILYEHAIYILNNCKRAIYDIKEYSGKIEGIIDIACSSIPE
                     TYILPDFMKSFSMSYPDVKFSISHYDSQYAISEILNERISFGLVGSKINNPQIEYLDL
                     LDDELVLITPSDFKIDNKNNCIDIGELAYLNFIMRKEGSGTRNLILNTLSKNNFPVSK
                     LNVIAHVESNEAIKEMVRLGLGVSFISYISAIDYLNAGKIKCYKIKDVDFTRKFFFIY
                     SKKKTFSPLEDKFLNRLCEYFEIII"
     gene            complement(72564..73406)
                     /locus_tag="PC465_000720"
     CDS             complement(72564..73406)
                     /locus_tag="PC465_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2648049.1"
                     /translation="MTTSSKKLETISPDSKITRKDFWKCFRRSLTLDSSWNYERMQNI
                     AYAYMMAPIIRRLYKDDKEKKSKALKRHLEFMSVTPHISTLLVGISGAMEEENAKNKE
                     FDANSINAVKSSLMGPVSGIGDSFFWGTLKLIAAGVGIALASQGNIMGPILFLLIINV
                     PHFIIRYICLDKGFKYGTQFFKDVSGSSIVSKVMEAASMLGLMVIGGMTASNVMLKLS
                     VNVGSGEWAEPIQTYLDQIMPCMLPAMIFGIMYWLLGKKVKTTTILISVMIICIVLAA
                     IGVV"
     gene            complement(73390..74148)
                     /locus_tag="PC465_000721"
     CDS             complement(73390..74148)
                     /locus_tag="PC465_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2648050.1"
                     /translation="MEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNL
                     HTGIVIGSTLELVFMGAFPVGASNPPDFVSGSIIATAFVILTGQDVSAAVVLAVPIAT
                     LVLLIDNFLMTVVLTWGAHIADRYAEEGNIEGVERVQLLFGIGNKLILAIIVGIGFSL
                     GVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYL
                     NITVTGVALFGLAIALIYVNFVGEKEVIVDDNEF"
     gene            complement(74165..74635)
                     /locus_tag="PC465_000722"
     CDS             complement(74165..74635)
                     /locus_tag="PC465_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2648051.1"
                     /translation="MIKLVRVDHRLIHGQVAFTWTKFLSTDCILIASDDLLKDELRMA
                     GLKMAKPSNVKLVMKSIADSIKALNSGVTDKYNLLILCESVEDVYRLAKEVKAIKSIN
                     LGGTKSDDNRENISKAVHVSKDDIKMIKELDSEGVNVFVQLVPDDDATNVMKLI"
     gene            complement(74635..75378)
                     /locus_tag="PC465_000723"
     CDS             complement(74635..75378)
                     /locus_tag="PC465_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane biogenesis protein"
                     /protein_id="HDF2648052.1"
                     /translation="MKKKGILSVFKSKKPIIAMIHLKGDTPEDIFERAKKEITIFEEN
                     GVDGIMLENYYGNYYDLERILEYVSKANLSIPYGVNCLNVDTMGFELATKYNASYIQV
                     DSVVGHVKPRDEATLEEFFKLQRSKCPAYLIGGVRFKYQPVLSENDVEEDLKIGMTRC
                     DAIAVTENATGQETSMEKIELFRKNLGDFPLVIAAGVTLENAKKQLKLGDMAIIGSYF
                     KDNYKDFGDVSVEHVKTFMDEIKKIREEL"
     gene            complement(75382..75795)
                     /locus_tag="PC465_000724"
     CDS             complement(75382..75795)
                     /locus_tag="PC465_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2648053.1"
                     /translation="MKKIILASHGDFSKGLLNAVKMIVGDLADCVSSYGLYPGQSASD
                     FALELEKTISEDKECEYIILSDLYGASVCTAMLRLTNLHNVRLFSGMNLNMVLELLTR
                     FSDELTVEDIDQLVEESRRGIQSVTLQIKEEEEVF"
     gene            complement(75821..76573)
                     /locus_tag="PC465_000725"
     CDS             complement(75821..76573)
                     /locus_tag="PC465_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2648054.1"
                     /translation="MDEKRQKKEMDLEVNSFVPLYQQLYDNIKKQIASGIYKPGDKLP
                     SEGDLCKEFNISRITVRNALNELVKEDILCKKRGKGTYVTIPERIEATCAGNSFTNSC
                     HRINAKPSTKIISVLIKKADKQVAEALSIELEEKVICIKRLRLIDEVPVIFEVDYFRI
                     DYMFLLKEELEDKSLMEVISNNISTLPKRVENIFEVKHSNKEYSDHLKCASNMPLLKV
                     RQSVYTENNDVLYYNEQFIRSDKYKYAVSAEI"
     gene            complement(76813..78207)
                     /locus_tag="PC465_000726"
     CDS             complement(76813..78207)
                     /locus_tag="PC465_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDF2648055.1"
                     /translation="MNLKYEFKNAWDFERKENTIEQIMQYSRNYMEFLSKSKTERLSV
                     KEIIKLAKENNYISIDEAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGS
                     HIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTAIPLALHGIVILNDGTKVDIS
                     IGEEDSDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNIPLEDEEKEPITANI
                     LKILNEKYNIVEEDLLSAEIEVVPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILE
                     TEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGDYCDIKVRRALANSK
                     VLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKGI
                     FNKGNVIWQTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIY
                     EMYKGYKAFFNINL"
     gene            complement(78227..78436)
                     /locus_tag="PC465_000727"
     CDS             complement(78227..78436)
                     /locus_tag="PC465_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HDF2648056.1"
                     /translation="MFDKKKLDRINELAKKNKEGILSADEIKEREILRKEYLENFRAH
                     FRSRLDSVKVVSPEEYEQYMKNNKN"
     gene            complement(78465..79910)
                     /locus_tag="PC465_000728"
     CDS             complement(78465..79910)
                     /locus_tag="PC465_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2648057.1"
                     /translation="MEKYRIDLNEKKSTKYIQIFNHIKELIINKELVEHEKLPPIRKL
                     SNFLQVNNTTIVKVYELLENEGYVYKIIGSGTFVSSLNSYKSGIDNRKNKIIVQREDL
                     IHFDNGNPSNDMFPIDSFKNAVNMALSKDGSSIFEYDEGLGSEELREKMVEYLSDGNI
                     KTTKENIQIISGAQQGIDIVCKGLISYSDVVFMEEPSYNGAIEVFKSRGAKIISIPML
                     DDGIDIGILKLKLEKIKPRLIYIMPNFQNPTGISYSTYKKKKLIELAEEHDFYIIEDD
                     FISDFVFESKDNRTIRSYDDKNRVVYIKSFSKILMPGLRIGIVEMPNELLKKVLWAKY
                     SSDISTPGLIQKSMYYYMNNFDWKNYLSHIEKIYTDKYKLAKNLINDKLSGKLKVRKS
                     CGGINFFLELPRGYTSQAFTNFMLNKGVSMLPGTYFFDNLVDDRFFRINIARPSMEEL
                     EKGISIISDNIDEFFCEYKNKLDIKSNKLFY"
     gene            80020..80814
                     /locus_tag="PC465_000729"
     CDS             80020..80814
                     /locus_tag="PC465_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HDF2648058.1"
                     /translation="MFYDYHMHSSFSTDGKSTMEEMVKKSIELGLEEICFTDHVDYDV
                     YADDSFSIVYEDYFKSLETLQSKYKDKISIKKGIEFGVQTQLMDTYKKEAHQYPLDFI
                     ICSIHAIDTMDLYLGNYFKDKTQHEVYENYYLYLYNIVKNYKDYSVLGHLDLIKRYAP
                     YDTILDDRLFSDIIEETLKQAIYDGKGIEINTSCYRYNLPDLTPSKYILQMYKDLGGE
                     IITTGSDSHHISQVACEFDYIYSLLKNMGFKYVSKFNKLKPEFIKL"
     gene            80865..82187
                     /locus_tag="PC465_000730"
     CDS             80865..82187
                     /locus_tag="PC465_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDF2648059.1"
                     /translation="MKVPYLVLSTVILFISNFIVRIFGFLYKIFLSRALGETGLGIYH
                     MIFNFLMICLAVTTTGIPTALSCLVAKRKALNDRHNTNALFISTLYISFFVALIISIV
                     ASFNSSFLSLKFLKDAKLNLFILAVCPAIVIITLSNVLRGYYYGIKNVKIPAIGQIIE
                     QIGKILFVFLLVMYINNKSMNCYIALLGISIGELSNIIFMLICLWRDSSFDNRYIISI
                     KDFYNSSMETLKMSIPITCNRMSNILLQSISSMMIPSRLALSGMTYQQSLSMYGIVSG
                     MVMPFIFLPFTVGSALIVNLIPTISQEIALRKRKSVIKKIKYSILLTLFVGILSSIFF
                     YFFGKDLCILVFKNTLAGEYLKAMFLVPLFMSLNQTLSGILHSIRKELASSINTITGM
                     LIQLIALYVFLPIPGLNIYAYIYTMTIVSIFTCLLHTIVLFKSLKSIR"
     gene            complement(82287..83504)
                     /gene="cdeC"
                     /locus_tag="PC465_000731"
     CDS             complement(82287..83504)
                     /gene="cdeC"
                     /locus_tag="PC465_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeC"
                     /protein_id="HDF2648060.1"
                     /translation="MQDYKKNKRRMMNQPMSTMNEEEVYTDEINSEDMRGFKKSHHHN
                     GCNTDNKCECHDDCNPCNPCNPCKPNPCNPCKPNPCDDNCGCHDNCKCDCEPCEMDSD
                     ECFENKCGPECCNPISPRNFSVSNAVPFAIEANRIFDTMQFQTFTDATGPNGEPLTFE
                     TEVVEVFGSVPSAGQASVTIEKICLSNDGIVIDTGMTTLEDFDLDPLGDIVGRNCETT
                     FEFAVCGERNSECCRQGKGKSVAYKQRGLTVAVRNLVLELRGRCGCTEFVALAFPAVR
                     AGGGCKRRVDYVEFTFNTLSAPICLPADGRAVTLRQEYQTNLTVDCIGKSILKLECNE
                     CCEPFYELIIPNDIDLVLCLQETVSTLISEQIVVLASPNPIQPRLVDTFSKVCDFSQC
                     GPNHGSGKPSCHR"
     gene            complement(83687..83867)
                     /gene="ssrS"
                     /locus_tag="PC465_000732"
     ncRNA           complement(83687..83867)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="PC465_000732"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(83982..84887)
                     /locus_tag="PC465_000733"
     CDS             complement(83982..84887)
                     /locus_tag="PC465_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648061.1"
                     /translation="MNNLLFLIGVIALSNGNISIFDDKNKSKGNNRVRKNKKNANDKL
                     SQSTHGNLRFDANDIKRGLRLMDLSEEDLEMGMEIITRTKKYMSRDERKILIKIESVL
                     DLVRGIKKLNNIDMVDTEDETDFFRKMDSDDKKNMMIKEIIDVFPEKRKNSVEKAIGM
                     KKKIDLFAELFLPDDFGEGGFSLSSLANINNLGSMNNLKLLGSLLRGDDSNNDDEDNN
                     DELNYEDEELDCEDKELDDDELTDEGEMEDNEDELVEDKNTGYENIENDEDIVYDEEL
                     YNINEQESEYNYNEKNTKTRAKKKR"
     gene            85099..85497
                     /locus_tag="PC465_000734"
     CDS             85099..85497
                     /locus_tag="PC465_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648062.1"
                     /translation="MKKLDTESLEKMAKQKNIDKDKIEKMADSYKGKSENELMEELIK
                     IGKNLDGRDEVVSKFKAFLDENQRKKLDNIMEKISDAENQRDTKPAKTKKAKPTKGKS
                     NSPAPKNTPGSQQKKSKSLFKKTKKSNPHE"
     gene            complement(85620..86636)
                     /gene="ccpA"
                     /locus_tag="PC465_000735"
     CDS             complement(85620..86636)
                     /gene="ccpA"
                     /locus_tag="PC465_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator CcpA"
                     /protein_id="HDF2648063.1"
                     /translation="MKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEVIK
                     ETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANTYS
                     DKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYTVS
                     TSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKSLI
                     KYGGTDYESGYNSMKELLDDGIIPHAAFVTGDEAAIGAINAICDAGYKVPEDISVAGF
                     NDVKIARMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKKIELPYRIVDRESVT
                     ERKK"
     gene            complement(86889..87089)
                     /locus_tag="PC465_000736"
     CDS             complement(86889..87089)
                     /locus_tag="PC465_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648064.1"
                     /translation="MLDRFFGEEGGFGGGGWWIIVLFFLFLAFEDCWRDIDIMSWIPF
                     LILLLITCSCGGFFDGEVGCGC"
     gene            complement(87123..87302)
                     /locus_tag="PC465_000737"
     CDS             complement(87123..87302)
                     /locus_tag="PC465_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648065.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFGDSWAEFDIMAWIPF
                     LIVLLILCCCGGCLE"
     gene            complement(87484..87690)
                     /locus_tag="PC465_000738"
     CDS             complement(87484..87690)
                     /locus_tag="PC465_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648066.1"
                     /translation="MTKLEDNMERFFGGCEGFFGNKMLIIIVIVFLLLCTDILEDLLC
                     DDNIWIWVILIVLLLFNFDDGCCC"
     gene            complement(87738..88163)
                     /locus_tag="PC465_000739"
     CDS             complement(87738..88163)
                     /locus_tag="PC465_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648067.1"
                     /translation="MKYVGLLLTSVGMFLLIAVNFYYNSITLDMQRIEDYVMETNLIL
                     EDVAEKESYVSNEKEDYISRLMHVKKGIENSKTSFLIERYKEYKIKSIESLIYTISEE
                     KKDYLDEVDRYNKLGEKEINKLINKNFLEVTYLSITTYI"
     gene            88335..88562
                     /gene="acpP"
                     /locus_tag="PC465_000740"
     CDS             88335..88562
                     /gene="acpP"
                     /locus_tag="PC465_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDF2648068.1"
                     /translation="MFEKIKEIIAEQLGVDNLDEITMEASLMDDLEADSLDAVEIIMA
                     LEDEFGIEIPDEEAENFKCIGDICKYIEENK"
     gene            complement(88706..89710)
                     /locus_tag="PC465_000741"
     CDS             complement(88706..89710)
                     /locus_tag="PC465_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HDF2648069.1"
                     /translation="MIIHKFIIHVLDKNSDVPILNDFEGKVNQEVDGFFQKAIKRIAK
                     DEDLRKGVFKDYNDNLIKNCCEQIIYDESTFLKNSKEIASYLFDVMKINAALESCDLA
                     ICLYTIKDEKSVAILKLDYKKLYTHSIEFVDDKFNIQMVSNEIGIPETLRQKQGALIS
                     LSGINDEFHLRLLDKDAEKEGSESKFVTEFLNAKKIDDDKYKTKVFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLKEKHEVDINDFVDNSIKDDELKDSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRSIKTDNGFDIKGNLTDFEDPMKYTVKQNQDGTIDIIIKNVTFYEEK
                     "
     gene            complement(89724..90626)
                     /locus_tag="PC465_000742"
     CDS             complement(89724..90626)
                     /locus_tag="PC465_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDF2648070.1"
                     /translation="MFKKENQRYNLISYTNEEEMTLKEVLLDKLNFSVRSLSKMKREK
                     SVLVNGVYKKPSLKVYSGDLIEVKIDEEKANFEPQDLNLQIIYDDFDIIMVNKPPFMV
                     VHPTKSHYDKTIANGISYYIDNQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSTA
                     MSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRIIDERGQSSVTHYKVIERL
                     ENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGYVDEELINRQALHAYKLEFEQP
                     RTKEKLKFKADIPEDMKELISKLR"
     gene            complement(90821..91996)
                     /locus_tag="PC465_000743"
     CDS             complement(90821..91996)
                     /locus_tag="PC465_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HDF2648071.1"
                     /translation="MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANIT
                     PDMIDESLLGGVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLI
                     ALGDADIMLVGGAENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGIT
                     AENIAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEY
                     IKPGTTMEKLAKLRPAFKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIV
                     SYGTAGVDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDM
                     NKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR"
     gene            complement(92083..92928)
                     /locus_tag="PC465_000744"
     CDS             complement(92083..92928)
                     /locus_tag="PC465_000744"
                     /EC_number="1.1.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="HDF2648072.1"
                     /translation="MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLD
                     KNLTKLVTKGKMDEATKAEILSHVSSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLD
                     ELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVT
                     FDTVFELSKSINKVPVDVSESPGFVVNRILIPMINEAVGIYADGVASKEEIDEAMKLG
                     ANHPMGPLALGDLIGLDVVLAIMNVLYTEFGDTKYRPHPLLAKMVRANQLGRKTKIGF
                     YDYNK"
     gene            complement(93026..93823)
                     /locus_tag="PC465_000745"
     CDS             complement(93026..93823)
                     /locus_tag="PC465_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HDF2648073.1"
                     /translation="MSTSDVKVYENVAVEVDGNICTVKMNRPKALNAINSKTLEELYE
                     VFVDINNDETIDVVILTGEGKAFVAGADIAYMKDLDAVAAKDFSILGAKAFGEIENSK
                     KVVIAAVNGFALGGGCELAMACDIRIASAKAKFGQPEVTLGITPGYGGTQRLTRLVGM
                     AKAKELIFTGQVIKADEAEKIGLVNRVVEPDILIEEVEKLAKIIAKNAQLAVRYSKEA
                     IQLGAQTDINTGIDIESNLFGLCFSTKDQKEGMSAFVEKREANFIKG"
     gene            complement(93842..94852)
                     /locus_tag="PC465_000746"
     CDS             complement(93842..94852)
                     /locus_tag="PC465_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDF2648074.1"
                     /translation="MGNVLVVIEQRENVIQTVSLELLGKATEIAKDYDTKVSALLLGS
                     KVEGLIDTLAHYGADEVIVVDDEALAVYTTEPYTKAAYEAIKAADPIVVLFGATSIGR
                     DLAPRVSARIHTGLTADCTGLAVAEDTKLLLMTRPAFGGNIMATIVCKDFRPQMSTVR
                     PGVMKKNEPDETKEAVINRFKVEFNDADKLVQVVQVIKEAKKQVKIEDAKILVSAGRG
                     MGGKENLDILYELAEIIGGEVSGSRATIDAGWLDKARQVGQTGKTVRPDLYIACGISG
                     AIQHIAGMEDAEFIVAINKNPEAPIFKYADVGIVGDVHKVLPELISQLSVAKEKGEVL
                     AN"
     gene            complement(94871..95653)
                     /locus_tag="PC465_000747"
     CDS             complement(94871..95653)
                     /locus_tag="PC465_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF2648075.1"
                     /translation="MNIVVCIKQVPDTTEVKLDPNTGTLIRDGVPSIINPDDKAGLEE
                     AIKLKEEMGAHVTVITMGPPQADMALKEALAMGADRGILLTDRAFAGADTWATSSALA
                     GALKNIDFDIIIAGRQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFE
                     DCCHDLKVKMPCLITTLKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEVDPSNLGLK
                     GSPTSVFKSFTKSVKPAGTIYNEDAKTSAGIIIDKLKEKYII"
     gene            complement(95712..96848)
                     /locus_tag="PC465_000748"
     CDS             complement(95712..96848)
                     /locus_tag="PC465_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HDF2648076.1"
                     /translation="MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKM
                     AKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGN
                     EEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAI
                     AGDIYVVMAMTDKSKGNKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRI
                     PKENLLGKEGQGFKIAMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSK
                     FQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGVEAAMAKLFAAETAMEVTTKAV
                     QLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK"
     gene            complement(97557..98024)
                     /locus_tag="PC465_000749"
     CDS             complement(97557..98024)
                     /locus_tag="PC465_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HDF2648077.1"
                     /translation="MSISNVREYFKQFGKEDSILEFEQSSATVELAAEAAGVIPARIA
                     KTLSFKIGDDAILIVTAGDAKIDNKKYKAEFNCKAKMLTPEEVLEFTGHAIGGVCPFG
                     LKNSIKVYLDDSMKRFDTVFPACGSSNSAIELTCEEMEKFSKCEKWVDVCKNW"
     gene            complement(98103..98645)
                     /locus_tag="PC465_000750"
     CDS             complement(98103..98645)
                     /locus_tag="PC465_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648078.1"
                     /translation="MKKFIKVSFFILGIFTLFIAINKLVYRDMVSVKDYEINHLEEIV
                     FDFDSRRSRDVGTIVRFKISNNSKYSYKLNSAKMKFENCVENKKGMNKCSAYVNVDLF
                     NEKNSITERTLKYGIKPNNQGYVDFVIPKGLNFDYRYFNESGMSVEYKGEYIVNIPMA
                     KGLYLVVGKNNDTWNANIME"
     gene            complement(98697..99383)
                     /locus_tag="PC465_000751"
     CDS             complement(98697..99383)
                     /locus_tag="PC465_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HDF2648079.1"
                     /translation="MFNLIRKDLIIGISSDGIRNLKYILLFFVFYFFLNSISYYTVSI
                     VVSYLIFINTFECDYENDSRIFIRSMPVSIEDIVYSKYLLGVGLIISVTIIVSLLSKL
                     TSLVFFRNMVLNDVFFSVNIFLAILTILLPLIFKFGYGKMKVCGFIVSILIYFVYGSL
                     LKMISMIVYQVKHFNYSKVGGVYLSNYVTDIANTKYINLYSMTFLTIIIFIISMYFSI
                     KISKKNKFNY"
     gene            complement(99383..100243)
                     /locus_tag="PC465_000752"
     CDS             complement(99383..100243)
                     /locus_tag="PC465_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2648080.1"
                     /translation="MFSIRNITKKLGKFKLNNINLELKEGDIVGIIGPNGSGKTTLIK
                     IIMGIIDADEGEIELCNETIENSPISFKNNIGFVYDSLQFYPHLKVKEFRKIVSLFYK
                     NFDRERFDEYLNKFDIEENMHIENLSKGQSEKLMLSSALSHNAKLLILDEPTAGIDPI
                     VRTEIMQYLQDFVKNGSSSVIISTHNTDNLIKIADYLVFINRGNQIFTVKKELIEQEY
                     KIIRANKAELEAIKESIVGVKEYKYYNEALVKVGDSLKVKSLLIEIDKHKVKNPTIEE
                     LMYYYVNEVR"
     gene            100378..101178
                     /locus_tag="PC465_000753"
     CDS             100378..101178
                     /locus_tag="PC465_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HDF2648081.1"
                     /translation="MKRIITINTNQLNKSLETKELLTRKLINAGFEVYSDIYPDTELI
                     ISIGGDGSFLRTVRDFDFPEIPIMGINTGHLGFFPDILPDKIDSFIEAYTKKDYIIQE
                     MSLLNAEVYTTTSGSNMLAVNEVVIRGDKSRTIHLNLSLDNKHIQNFSGDGMIISTST
                     GSTAYNYSAGGSIVDINLELMQITPLHPINTNAYRCFTSSIICSNESVIKIAPEYRFE
                     DSVLIVVDGVEHRFRQIENIKVSISDAKIKLLRMSNYEFWHRVSEKFL"
     gene            101203..101772
                     /gene="yfcE"
                     /locus_tag="PC465_000754"
     CDS             101203..101772
                     /gene="yfcE"
                     /locus_tag="PC465_000754"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HDF2648082.1"
                     /translation="MKIGIMSDTHGSLLYFEKALNVLSDCDVLLHGGDVLYHGPRNDI
                     PEGYNPKKFIETLNKLENIVIVKGNCDADVDQMVIEHPIQSPYVMSQFGEIRIILNHG
                     YIESEEEIIDKAKKMGGDILVLGHTHVKKLYMDDNLIVINPGSTSIPKDGSHSVAIID
                     IIKTDDEDELELDINLIDINTGNIININD"
BASE COUNT        32417 a        18551 c        10918 g        40071 t
ORIGIN      
        1 aaggagtatt ttatgaacat acttggatta atagttgaat ataacccatt tcataatgga
       61 cacatatatc atttatctaa atctatagaa aaaacaaatg caacacatac tgtagcaata
      121 atgagtggaa attttctaca aagaggcgaa ccagctttat ttgataaata cactagagca
      181 aaaattgctg tcgaaaatgg tgtagactta gttatagaat taccaacttt atttgcttgt
      241 caaagtgctg aaattttttc tcatggtgct ataacaattt taaattcact aaactgcata
      301 aattctatat gttttggtag tgaagaagga aatacagaaa ttctttataa tatagctgaa
      361 attttagcaa atgaaccaaa tgaatttaag ttacttttaa aaaaatattt agatgatggt
      421 ctgttatttc caacagctag agctaatgca ctttttgatt atatacatca agacaaaaaa
      481 aataatttta tacaaaatta ttcaaaggaa caattatcaa aaacattaaa ttcatcaaac
      541 aacatactgg gtatagaata cataaaaaac ctcatccatt taaacagtag tataaaacca
      601 tttactatct ccagggtcca atcagaatat aattccgaag aaattgagag tgatatttgt
      661 tctgctactg ctataagaac ttcacttaaa gaaaatacag acctttttca tttaaaaaat
      721 gttattccag aaaaaactta taacatccta aatgaaaaaa tagataatgg ttttttacct
      781 atgtttgatg acttcttctt tgatatttta aaaacaatta tacttagaga tatggacact
      841 ttaaaagagt attttgaagt aaatgaaggc atagaaaaca gaatctataa agatatcttt
      901 acatctgaat ttctacatga actacaatta gcaattaaat ccaagcgata cactttaacc
      961 aaaatcaaac gaactctaaa caatatattg ctaggtatta aaaaaagcga catgcaactt
     1021 ataaaaaaca tagatactat accttatata agaatacttg cttttaatga taaaggtaga
     1081 gaaattctaa aagagataaa aaataaatct gaaataaaaa taataaacaa gttttcaagt
     1141 atatcatttt cattagatga tacgattttt aaaacactca taagttatga tataaaagct
     1201 acaaatatat ataatttaat atattataaa aacaataaag atttagtaaa aggccctatg
     1261 gatttttata ctcatccaat atatgtaaag tagtttttta aaataactat atttataaaa
     1321 atcattttat taactcttta ttatataaga tacaatagtc ttactttatt tatgtacaca
     1381 tgcttttagg atgacaacat caacttaaat attatattac tttctaaatt taagtaaata
     1441 ttgccatcct aaaaatttta caatttagct tcagatttaa aagtaaagtt taaaatatta
     1501 tatttaaatc taatttaata ttttttgttt tgtaaatatt attaaattaa tatttctaat
     1561 atattttccc tggatttaaa atatttttag ggtcaaaagc taactttata tttttaatta
     1621 acatcatata agcatctgaa tttgattcat gtaagtactc ttttttagca tatcctatgc
     1681 catgttcacc agaaacttga ccactaagtt ctctagattt tttatacata tagtcaaaag
     1741 tttcttttaa tcttattttc catgtattat catccatacc atcttttaaa atatatatgt
     1801 gtagatttcc atctcctgca tgaccaaaac tttttattct tatttttaat ttgtcttgaa
     1861 gctcgtgagt gtatcttata aactctgcta tcttatctct tggaacaacg acatcacatt
     1921 catccatttg tgtcgtagat gcctttatag cttctaaaaa tgcacctctg gctgaccata
     1981 tagaatcgtt tctttcttgt gtatctgata taaatacatc taatgcacca ttttctaaac
     2041 ataaattagc tactttttca tattcttttt ctatatcttc agtgctattt ccatcaaatg
     2101 taagcaaaag ataagcatct gatgtattat ctggaaactt tttacctaaa aattcttctg
     2161 ctgccaatat tacatctctt tccataaatt ctatagccgt tggtattgat tttgatttta
     2221 ttattttagg aacagtttct attgccattg ataaatctgg aaatggtata agcaaactta
     2281 tacttttctt tggtaaagga agcaatttta atatagcttt agtaactatt cctaaagtac
     2341 cttctgagcc cactaataaa tcctttatac tatatccaga actattttta accacctttc
     2401 cacctacatt tataatttct ccatttggta gtacaacttc aagacctctt acataatccc
     2461 ttgtaacgcc atattttact gctctcatac cacctgcatt agtgtttata ttacctgcaa
     2521 ttgtagcact tttttcacct gggtcaggtg ggtaaaataa atctctatct tgaacatatt
     2581 gacctattgt catcaataaa acacctggtt ctactgtcaa tgttaaattt tcataatcaa
     2641 cttcaagtat tttattcatt ttacatagat taatcattat tccaccattt atggcaacag
     2701 cagcacctac aagaccagta ccttgacctc ttggtgtgac tggtatatta tttttatatg
     2761 cgtatttcat tattttagat acttgttcag tttcaagtac atttactaaa acttcagggc
     2821 acttctcaat ccctccaagt tcatcatgtg aaaaatcttc atttatatca cttccaacta
     2881 atacattttc ttctccacaa gtatctatta aaaaatctat atctttttta tcgattaatt
     2941 tatacatttc tatcccccta tttagctgct gatgccatat atttttgatt attatctttg
     3001 ttattttcta ttttttcaat caatttagga ataatatcat aaatatcacc tattaaagct
     3061 aaatgtgcta catcaagtat aggcgcttta tcatctttat ttattgctac tatatagtca
     3121 gcaccctgca tccccgcaac aaattgaaca gctccagata caccacaagt tattatcaat
     3181 ttaggtttta cagttctacc actaagacct atttgttttt tagcatctat ccaacctgct
     3241 tctattacag gtcttgttcc tgccacttga gcgtttaact tatcagctaa tttatatatc
     3301 atctccatat cttcttgttt ttttattgct ctacttgcca caactatcac ttcagcttct
     3361 tccagaccaa cttctttatt tttttctttt acactcagta ccttaatttt agattttagt
     3421 tctttttttt ctactttaca taaagttatc tttcctgtag tattctctat tttttctggt
     3481 gctgaaaata ttttatatct tacagtggca aattgtggtc tattattagg tgtgtttata
     3541 tgagccatta tatttccacc aaatgctggt cttatttggt ctaaatcagt atttgattga
     3601 atatcaagta ttgtacaatc tgctgtaaga cctgttctaa atctagcggc aagtcttgga
     3661 gctaatgacc tacctaatgt agttccacca actaatacta tcgttggttt tattttatct
     3721 ataaagtttt ctattgcttt tgaatatggt tctatcctaa aatctttaaa ttcatcttca
     3781 tcatatacaa atacttcatc caccccataa gaaatcaaat tactgcactt atcttttatg
     3841 tcttttccta caaatacaca atacacaggt tgttttattt ttgatgccat ctcacgagct
     3901 ttacctataa gctcgtacgt tacaggatgt atatttccat tatgatgttc aacatatact
     3961 gcaattcccc tccattcatc tttattaatt tgtactttac tactctctat aaattcaaat
     4021 gcgccttttg gtccactttt gacacacaac ttgcacatct tacagccagc acttatttct
     4081 actatacctg acttttcttc tatagcccca aaaggacata tttctaaaat tctctttaag
     4141 tcagttattt tatcttgatt tacaactatc tttgacattt attactcccc cttacaccaa
     4201 ctttaattcc tctaatttat ttacaagtgc aaaacttagt tcatctgcat ttcctcttac
     4261 aatattttta tctgtatttg gctttggagg aaatattctt acaacttgag taggagaacc
     4321 attaagtcca tagttatttt catctttatc ttcaaagtca tctaagctat atacaggtat
     4381 ttctctatct ttagtattaa gttttaattt aaatgaaggt agtcttggtt gaaaaatgtc
     4441 tttttctaca gttattaaac atggatattc aatctcacat acttgtaaat catttggcat
     4501 atctatttca acaactatac tttcatcttt aacttcaatt aattttgtaa cgttagtaac
     4561 atgaggtata tctaaaaatt cagctacttc aggtcccacc tgtgctgtat caccatcagt
     4621 agtttgtttt ccacaaatta ttaggtctac ctttcccatc ttcttaatac cttgtgatat
     4681 ggtataggaa gtagccaata catctgctcc tccaaatctc ctatcactta ttaatgctcc
     4741 ttcatcagct cccatcataa aactttcttc aattaccttc tttgcctgag gaggacccat
     4801 gctaagtact tttagattcg ctttcttctc ttcctttatt ctaagagctg tttctaaagc
     4861 atataggtca tagggattca tttttgaatc tactccatct ctttttagta ctcctgtagt
     4921 ttcatcaact tctactgaag tcgttccagg aacttgttta atacatgtca aaatttccat
     4981 aaagtacact ccttttttat ttaactataa ctgatactcc atcaggtata actactactt
     5041 tgctctcctt accaactata ctattcgcca tttctaaagc ttctttaaag ttaaatgcat
     5101 gtttcatatg catttttttt atcatttcag gattacactt atctgttacc attatcacag
     5161 tatatttaga taatattctc gctagtatct gaaattccca ttggtctgga atcgtatcta
     5221 ctctatcgac acttctaatt ttatctaaaa gttgttttgg agaatctgca tttgctacat
     5281 tttcataaaa agattgacct ccatgaccat cattacatgc tgaaatcatt attattactc
     5341 caccgtcttt acaagtagct tcagctgctg tcattccttt aacagattga taaatatttt
     5401 ggtctagtgg atatccacca tttgtagtta caacaatatc agattttata gaatttactt
     5461 ttgataactc tgttacaaat ctacatcctt tagtatgtgc tttttcgaca tcaccagcaa
     5521 aggaagcaat tattttttta tctttatcta ttacaacatt caatatgaat gctaattttg
     5581 caactttagc tgcatatacc atatcctcat gaataggatt attattcaat tttccagttc
     5641 ttgaattatc actatctata aagtcactac agtgattgta cattatagtc tttgcagatg
     5701 cgattcctgg aagtacgctt tttctgccac ctgaaaaacc tgcaaagaaa tgaggttcta
     5761 taaaaccttc tgctatcaaa agttctgcct catatgctag tttgtttata tataaatctc
     5821 cacctgaagg caatatccct actttacaca tagatttatc atcagtagat atatgcataa
     5881 ctatatcttc attatctact atttcttctc ccattttata aattagctct tcccttgtac
     5941 ttggcctatg aaatccagtt gccactataa tcttcacatc aatttctgga ttaacattcc
     6001 taatccttct taatataatt ggcatagtta ttctacttgg tacaggtctt gtatggtcac
     6061 ttgtaattat gactacattc tttttcccct taaccagttc ttccagagaa ttagagccta
     6121 taggattatt catagattct tcaactatct cttcttgagt cttatgttct atataattat
     6181 ccgattttga ctccaaaaca ccgagaaaac gttcatcagg tatttctaaa atcattcctt
     6241 gttttgaata cggtactttt aactttacca tttttaatct cccattataa taaactataa
     6301 aattggtatg tggtcatacc agttttacat ttatatgata gtaccattat ctaccatttg
     6361 caagaataat ttattttata acaaactttt aattttcatt ttttctataa tttttactta
     6421 taaaatccat atgttccttt gctttctcac atgcaagttc tacatcattt tctacaactg
     6481 cattgtatat agcttcatgc tgtttaagca atatattttc attaaaaggt tctgcgatta
     6541 ttttttctct tgcatcttct ataaatccat caaataattt tgatgctgtc ataaaaagac
     6601 tttgaattaa ataattttta cttaatgttg ctagtttact gtgaaatttt tggtctaata
     6661 acaccagtac tcgattatta tcttttttat tagtttctac cctcatttca tctattatat
     6721 gtttcaattc tataacttca gaagaagtta ttctctttga agcaagtttt gcaatctcaa
     6781 tttctaggat tattctaagc tctaatatat cttcaagtgt accattatta agtttaaaaa
     6841 tcatagataa aggttctatt aaagtttttt ctatatttgt acatataaaa tttccttcac
     6901 cctgtctgct ttctatcact cccatagtct ctaataccct aatagcttcc cttatggaag
     6961 ttctactcac attcatttgt tcagacagtt ctctttctga tagtaattta tccccctttt
     7021 ttaactctcc atttagtatt ttatattgta tttgctcaat tacttgttca taaacttttt
     7081 tactagctat actattaaac attttttcct ccaatatgat aatcgttgtt gtaatatata
     7141 tctattatat atcttaagcc attacattca tatattttta ttacttttaa tataatatct
     7201 tataactcaa atttacaggt gatattatga aaaaaaataa aattattgct ttttttgctc
     7261 catctatcat agttggagtt ctagttttag ggattatcct atacccaaat gaagctataa
     7321 aatctgcaag agaaggcttt tctatatggt ctaatgtttt agttccatca ctactaccat
     7381 ttataattgg agcaaactta attgttgatt taaaaatagt ggatattata gggtttatca
     7441 tcaatcccat aactagattt gtatttaatg tttcaggaaa gagcgcttta gcttttgcta
     7501 tatctacagt atctggttat ccagtaggag taagtttagc ttctgaattt aggagtaatg
     7561 gacaaatttc taagtatgaa gcacaaagac ttgtgtcttt ttgttctaca tcaggacctt
     7621 tattcataat aggttcggtt ggtacaggta tgttccaaaa ttcaaactta ggttatttaa
     7681 tgattctctg ccattatcta ggaactatat tggttggtct tttctttaga aattatggta
     7741 atgaaaacct tccaaagaca aaattggatt taaaaacaaa tataaaaaat gtaatcaaca
     7801 ttagaaattc aagtgggaat ggtttttttg ttttatttgg aaatgctgta tttaatggag
     7861 taaatacatt acttacagtt ggtggatttg taattgtttt ttcagtagta tttaaaatac
     7921 tatctctttt taatgtaatc tcattaatag catcagttat atatttgcct ctttcatttt
     7981 taggtgttag taaagaactc tgtcaagcat ttgtaagtgg tctatttgaa attactatag
     8041 gatgcaataa agtatctagt ataacaagtt ctccagaaat tttaagagca tctttagcta
     8101 gttttttgat aggatttagt ggattatcca tcctagctca atgttgtaca tttctatcaa
     8161 aaacggacat agatttaaaa ttatacatac taagtaaatt tgcgcatgga gttttagctg
     8221 ctatctttat atttatactt tatccaattg caaactctgc tgtgttggtt tctagctttg
     8281 ctgatacata caacgttata tataataatt taatctggtt ttattacctt agctattatg
     8341 atacaattat tcaaattgta gtaataattt atctaatctc agccgtattt attgcaaaaa
     8401 aacatatgaa aactttatct acaaatggga aactaatgcg atataaaaat acttttttca
     8461 ctaagaaatt ttcacgaaaa aaataaaact aataaaactt aactaaatac ttccattttt
     8521 ttattatatt tgtcataatt ttaataacct ttttaattag tttaacagca tagttatttc
     8581 atcacaattt aataatttta ttagaaatat ttttcaaaaa attctcctta atcacatata
     8641 tcacacttgt ataagtttac tggaaaattt ttccattata taatatttca tttatattat
     8701 ataataaata ccgacctaaa cttaccaaat caaactaaga ggagtggttg aaaatggcaa
     8761 caagacctat agaaatagac gaatataaaa agataatgga actattacat actggcttta
     8821 cttatagtga aaatggcgtt gaaaaaagat ttagaaaaaa tcctaaagtt gcattggcac
     8881 taatgttaga agctaattta ggtctaagaa tatcagatat tttaagatta aagataggta
     8941 attttaaagg taatatgttg gaaataaatg aaaaaaagac gggcaaatta cagtatagac
     9001 cagttaataa aaatataatt gagtccataa atgaacatgc aagaaagtat aatcttaaat
     9061 caaatgacta cttagtaaat ataaagacaa aggctattca aaaacagttg aggataattt
     9121 gtaaatactt aaatctgtat aatataagta cacatagctt tagaaagctc tatgctacta
     9181 ctcaatttga aaagagtaac aataatttag agttggttaa agaactttta aatcacagct
     9241 ctgtagccac tacacagcga tatataaggg taactcagca agctattaat gaagctagtg
     9301 aaaatttctt tattggttaa ttataacgta tacatttttc tattatctta ttaattcacc
     9361 agatattaaa aaagagtgtc tcaaaatgaa ctttttagtt catgagacac tcttttttta
     9421 taaaatcaaa tatattttta ttatttcaac actggaaaaa aggcttatct ctctattttg
     9481 agacacccta ttaaattttc ataattcttg cataaacata ttaatctatc ttcaataatt
     9541 ttttagctga ttcactgtaa ttatttcttt ttacaatttc caaaactcta tcaatctcat
     9601 gttctgactt tgcacttaca aaaatcgcca attcttcatc atctataata tcataactat
     9661 ctacatattt atctaaacat tctaaaattc catctttatt attataccca ccaaatctaa
     9721 ctactgcact acactcatct tctataagtc cacttaaatc caatttccct tttgaaaaag
     9781 actttatatt tgaacttcta ttatctatta tatctataat atctgcataa acagcacttc
     9841 ctgttgcacc tcttccagct cccttaccta caaaagaaag ttcacctact gaatcaccta
     9901 ctaaaataac tacgttgaac tcattatcta tctttgaaag catattatta ttgtccacta
     9961 atgctggtct aacaaatcca cttacttctc ctgattcata cttacttcta gcaaccaatt
    10021 ttatcttaca atttaatttt tttgcatatt ctatatcttt ttcatctatt gaagttattc
    10081 cttctaataa taaatctttc caatatacta tttttccata agataaagta gacaatatag
    10141 ataactttct agcactatca tatcctaaaa catctgcatc tggattaact tctgcaaatc
    10201 ccaactcttg tgcctgtttt aaagcgacat catacggtaa attttcatca tacatctttg
    10261 ataatataaa attacaagtc ccatttaaaa tagcgtttat gctctttata ttgttgcctt
    10321 ccagtgattc tatcaatggt tttaaaactg gaataccacc tgccacagat gcttcaaact
    10381 tgatgctaac attatttaag ttagctaatt ctataaggtc actacctttt tcagccagta
    10441 aatctttatt agctgtcact acatgtattt ttttatttaa cgctcttgtt acataatcaa
    10501 aagctggatt taatcctcca attacttcaa ctagtatatc aatatccttg tcaaatatat
    10561 cttctatatc agtagttatc ttatcaaagt acttcttata cttgtgtttt tctttatttt
    10621 taactaaaat tccaacaact tctatatctc tttttgaagt attattttct attaaatcaa
    10681 ttaatccact tcctactgtt ccatacccta atattgctat cttcactgta acataccccc
    10741 atcattttga ttatattaaa ttatttatat atataaatat accaataaaa aaagcttgag
    10801 tataaactca agccatatga cgggtttata ctcatctttc agcataaatg ctgcaggatt
    10861 tagcaccaat gtataattaa atatactggt tgccgggctt cacagggcca gtccctctgc
    10921 cactcttgat aagattgcta atttaaattt atgtttaata gtataataca atttcttcca
    10981 attgtcacta tttttttaac ttatttccct aaaaggatat aaactattat ctaacagctc
    11041 ttttagttgg tttacccttt tttgtaacat tattattttt agtctttgct ttcgcttgtt
    11101 catgtcctgg aaaaagtatt ttaggctctt caatattcct cttgtaaata gtaaatttaa
    11161 aaccaatagc ctgcacaaat tcagctctta aagcttcaca tactgcatta gcagtttctt
    11221 tagtatcaag acctgcattt tctaatatag taacttttac taattctcta gttcttaaca
    11281 taccatctaa ttgctctaag aaactctctg taacaccttc tttaccaatt tgtgtagtag
    11341 gctttaaagt atttgccaaa gatcttaaat acgccctttg ttttcctttt aacatattct
    11401 cacctctata attctatact taaattatct ataatctata tttaaattaa ttgtaaaact
    11461 caaattctaa ttcataaatt ttaaccacat ctccatcttc tattcccatt tctctaagtc
    11521 tatcaaaaac accttgactc tccatagctt tttggaaata ttgaagggat tccatatcat
    11581 caaaatttac agaatacatt attcttctaa gtgctttacc tgtaactaca tacacaccat
    11641 cttcaatatc tatacttaac tcttcttcag taccaatatc aagttctggt ctatacattt
    11701 cttcttctga aactagctcc acatcttcta cttcttttag cattttagaa acataggcta
    11761 ttacttcatc tatgccttga cgagttgctg ctgacatttt aaatactgta tatcctctgc
    11821 cttctaattc actcttaaac ttctcaaact tactctcatc ttctaatata tcaaatttat
    11881 ttgcaactac aacttgtggt ctctttgaaa gcttttcatt gtacaattta agctcatcat
    11941 ttatcttgtc aaaatcttca atagggtctc ttccctctaa tccagatata tctacaatat
    12001 gtatcaatac ctttgttctc tcaacatgtc ttaagaactc atgacctaat cctatgcctt
    12061 cagaagcacc ctctataatt ccaggtatat ctgcaagtac aaaactatct ccaaacttag
    12121 tttgaacaac acctagattt ggtgtaagtg ttgtaaaatg atagtttgca attttgggtt
    12181 tagctttagt tacaactgat agaaatgttg atttacctac atttggaaat cctaaaagac
    12241 caacatctgc tatcatttta agttcaagag ttatccatct ttcttctcca tctgtaccag
    12301 attttgcaaa agctggagct tgtcttactg catttgcaaa gtgttggtta cctttaccac
    12361 ctataccacc ttttgcaact atagctgtat ctccttcttt ttttaaatct gctaatacaa
    12421 gacctgtagc ctcatctctt attactgtac ctgctggtac ttttaatact aaattttctc
    12481 catttttacc agctcttttt cctttgcttc cgtcgccacc attttgagct tgatattttt
    12541 tctggtactt aaagtccatt agagttctaa gccccaaatc aacttcaaat atgatgcttg
    12601 ctccacgacc accatctcca ccgtctggac caccagctgg aacgtatttt tctcttctaa
    12661 atgctaccga accatttcca ccatttccag ccttaacaaa tattcttgcc ttatctataa
    12721 acaaattctt cacctactta attaaaaact tttaattagc attaccaaaa ataccattat
    12781 aaattcatca gtattataag aaaaaggagt gcctcaacac tccttttatg tatattactc
    12841 agctattgct actggatata tactaacttt ttttctcttc ttgtcttttc tttcgaattt
    12901 aacagtacca tcaactaatg caaataaagt atcatcacta ccttttccaa cattagttcc
    12961 tggatgtatt ttagttcctc tttgtctaac tattatactt ccagcagtta ctaattgacc
    13021 atcgaatctc ttaacaccta atcttttaga tatagaatct ctaccatttt tagaagaacc
    13081 tacccctttt ttagatgcta ataattgtaa attcatgttt aacatatgga gtcaccccct
    13141 acttttttaa aatttttata ttttttgggt attcccgttt aatttcttta accgctaatt
    13201 gaaagtgatt tagtaataat tgtgcgtctt ttacatgtgt atctttgact atacactcta
    13261 tatgaccttc ttctcctact actttttcaa attcaatctt ctgtaatttg tctaaagaat
    13321 ttataactgc aatagcatta gatgtaactg cagcacatac tatatcatag cctatttcag
    13381 caaaatcagc atgtcccttt aaacaaaaac cttgcaacaa gaaatcatca ttataataat
    13441 atttaacttt tatcataact taaccaataa ctaagcgttt attttttcta caactatctt
    13501 agtgtatgat tgacgatgtc cttgttttct tctgtaatct ttttttgctt tatacttgaa
    13561 aactataact ttcttagctt taccttgttc aacaacttta gcttgaacag atgctccttc
    13621 tactactgga gaacctaatt ttaattctcc atctttagag caagctaata cttcgtttaa
    13681 agtaacaaca tcacctgcgt tagcttctaa tttttcaacg aataatacat caccttcaga
    13741 aactttatat tgctttccac cagtctttac tatagcgtac attaaataca cctcctcggc
    13801 ctcaaactcg ccagtacaag gtacttcatt tgaagattta aacctttact gtgcggcatt
    13861 acaattatta attataaaat atttacattt tattgtcaac tattttatcg aaaataacat
    13921 tggttttatt gtgctttaat gtactatttg cgtttaaaga aatctttata ttatattttt
    13981 caccaatttt atcaattata tccatataat attcttttat ttgttcaaaa ataaaatcat
    14041 taaattctac cattatgttt ttgtaaacag tatgttcact tattctcata atttcttttt
    14101 caatactatc tagtatataa tgtacagatt ttattgtttg ttcaccatca caacatggac
    14161 aagacattaa ataatactta tcaatggatt ctttttctct acgcctagca acttctacta
    14221 aaccaagttt tgtcatacct aatacttcag cttttctttt atctttatta aattcttctt
    14281 ctaggatgtg taaaatctcc ttttgatgct tctttttatg catatcaata aaatcgatta
    14341 ttattatccc agctatgtct ctaattctaa gctgtcttac aatttctttt gcagcttcaa
    14401 gattagtttt ataaacggtt tcatcaagtt taccagttcc aataaactta cccgtattta
    14461 catctataac cgtaagagct tctgtttttt caattattaa ataacctcca ctctttaacc
    14521 atactttttt atttaataat ttttctattt tagattctat tctgtataaa tcaaatacat
    14581 ctctattttc ctcaagacac agtttatcaa cataagtctt atctatacct cttaaaatag
    14641 acttaagttc agagtactta tcataactat tggtaattat agattcaata tcatcattca
    14701 cattatcttt tacatattta gttgcaaaat ctaaagactt atataataat ttcggaccta
    14761 taccaagttt atattctttt aaaatgtttt catactttaa tttcaactct tctatatctt
    14821 tctttatttc atcatgagtg caaccttgag cctcagtcct tattattaat cctagatttt
    14881 ccttatttac tgccttagta atttttttta atctaaatcg ttctttttca tcagtaattt
    14941 tatttgatat tgtagttcta tcattggaag gtatatagac aatatacctt ccagaaatac
    15001 taatctcagt gtttaatttt gcgcctttag ttcctatttc ttctttattt atctgaacca
    15061 aaatatcctg accagatttt atagtacttc ccttttttaa ttgtaaataa gcaagtttct
    15121 taaatccaat atctacaaaa caagcttcta ttcctggtat aacttttttt acgattccac
    15181 gatatatatt ggatacagtc ttcttattta aattgtcttc aacaaaaagt tctgttaatc
    15241 tttcatcttc aagtactgct gttttctggg accctattag ggactcaata actatctttt
    15301 tcacaacttc acctctcgag cttacatagg agtcactaat tccccatctt ctaatacata
    15361 taaatctctt ctcaatatat caacatctaa tgggtcaata tcaagttcaa acatctctaa
    15421 tatctttggt ataagtatat tagtatttaa attagttttt gagcctgtag ctatagtagc
    15481 agtaagagta atatgttcat cttctaaatt taaaacatca aaggttctta tcataggtct
    15541 tatatctact tcaaccatct tacctttttt attctttttt gttatgatta tttctttatt
    15601 attcataaag tcaattactt ttctttttac aaactctttc gtcataggtc ttttcaaatc
    15661 tatattaaac aaatattctc catagtctat cacagaagaa agagaaggtg tttgtctatc
    15721 aatttctttt gctttgataa aatctatccc atctggaagt tgaattgata ctttatttaa
    15781 aaattcctct actgataaat catcttcttc tatttcaata tctacatact caccttgact
    15841 ttctgtccct aaagccaaag cattgccata actcatttta gggtgaggat taaatccttg
    15901 agaatgtgat aagtttattt cagctcttct aaacgctctt tgtaacaatc tctgaaggtc
    15961 aagatgtgat atatatatca tgtcgccttc ctttttaaat tttactctta ttatcttact
    16021 catattagca aagccccctt cctatatcat gtatatttat tccacaacca ttgcagttat
    16081 gtctacaatc agaagtgatt ttttcttttt tagcattttc gtcttctcta attaagaatt
    16141 ttttactaat acctacatct atatggtccc aaggaaatac ctcttcatag tttctatttc
    16201 tatgtgcata aaaatctata gaaagattat tcttttccat agcttctttc catatatcta
    16261 aattaaaatg ttctgcccat ccatcaaatt tagcacctag tctaaatgca tcatatataa
    16321 cttttcctat tcttctatcg cctctagcta ctactgcttc catcaaacta gtctttgaat
    16381 catgataatt gtattttata ttgttatttc ttaatttatt tactaaatgt ctctgcttat
    16441 taataacttc ttctgtagta tcttgaccat gccattggaa aggtgtaaat ggctttggta
    16501 caaatgtaga agtactcact gtaacactaa aacttctctt tagctttcct ccatttactt
    16561 ttctataaat atcaataact ttataagcta atttagctat accatctaaa tcttcataag
    16621 tctcagttgg taaaccaatc ataaaataca acttaacact attccacccc atctcaaaag
    16681 ctctttctgt tgcattttcc aaatcttctt ctgtaacacc tttatttata acatctctaa
    16741 gtctttgagt tcctgcttct ggagcaaaag taagtccaga ttttcttact tgttgtattt
    16801 tatcagcaat ttccattgaa aaattatcta atctaaggga tggaagcgaa atcccaatat
    16861 tattagatgc atattcatct accaaataat cagtcaactc tgataactta ctataatcac
    16921 tcgtactaag tgatgataat gatatttcat catatccagt attcttaact aatttatcta
    16981 atatttcttt aagtctttta acactctttt ctcttattgg tctgtatatc atacctgctt
    17041 gacagaatct acatcctcta gtacatcctc taaataattc tagtactatt ctatcatgaa
    17101 cagtatctat ataaggtact attagttttt ctggataatc tacagtctca acatctttta
    17161 ttatcctttt agtaggattt ttagtaatcc cttctctatt aggagttaca ctttgaactg
    17221 taccatcttc attgtacttg acatcataaa aacttggtat gtatactcct tctatgctag
    17281 atattttata taaaaaatct tctctagtcg ttttattttt cttccattct ttatactcat
    17341 ttactacttc taaattaacc tcttcacctt cacctaatat tactacatct acaaaatctg
    17401 ctaatggttc ggaattataa gcacaaggac caccaaccat tataaatggg tcttccaaag
    17461 ttctttcttc ttttaatatt ggtatattgg ctaaatctaa tatatttaag atattagtgt
    17521 atgaaagttc atattgaagt gtaaaagtga caaaatcaaa gtttgttata ggctctcttg
    17581 actctaatgc aaataatggt atactttttt ctctcattat attttccata tcaactgcag
    17641 gagaatacac tctctcacaa aatacatctt catccttatt tattacatca tataatatat
    17701 gactccctaa gtgactcata ccaacttcat ataaatctgg aaagcaatgt gcatatctta
    17761 tcaattcact attactagta tctttatgaa ttgaatttat ttcatttcca agatatctag
    17821 caggcttttc tacttttttt aagatttttt tcaagtctac tttattcatt tattaaaatt
    17881 cctccaaaca agctctttat ttttattctt atttataagt aatattatac acgataaaat
    17941 attttctatc aaaaatataa ctaaaatatt gaatttaaaa tacatattat tcacaaaata
    18001 gaatagctaa aaatatttaa gaatattttc tattaaattt ttattgaaat acaatttttt
    18061 tacaaagtat gatatattat aaacataaaa ctattgtttt acatgactta tcatgacatc
    18121 ttttgtttca ttcacctcaa aatggggtat gttacttata taatgataaa ttttaggagg
    18181 gttaaaaatg agtaaagttt ttgaagtaaa aaaagatatc tactttactg gcgtagtaga
    18241 tgaaggttta aaagtattcg acataataat ggaaactgag tttgggacaa cttacaactc
    18301 ttatttaatc aaggacgaaa aaacggtttt atttgacact gtaaaggcaa attttaaaga
    18361 tgagttttta agtaatttat cagaggttac tgatatagct aaaattgact atgttgtaat
    18421 tcatcacaca gaaccagacc atgcaggtag tttaaaatac ttattagata taaatcctaa
    18481 tatagaagtt tattgtacta aagctgccaa actatactta gatggtcaaa taaatagacc
    18541 ttttaactgt catgtaataa aagatggtga aattttaaat atcggtaaaa gaaatcttag
    18601 atttataact gctccattct tacattgggt tgatacaatg tttacttaca ttgaggagga
    18661 caagactctt ttaacttgtg atgcatttgg ttgtcacttt gcaagtgttg atgcagaggt
    18721 agtgaatagt gaagattatc taaaatcagc taaacactac tatgattgta tagttaagcc
    18781 atttgctaaa catgttttaa gtgctgtaga taaggtggta ggactaaaca tagaatttga
    18841 tactatattg acttctcatg gtccaatgct tactaaagac ccaatggctg ctgttaaaag
    18901 atatgttgag tggtctacag aagctgttaa tacaactaat caaaatcaag tttctatatt
    18961 ctacttatca gcttatagta atactttaga gatggctaaa aagataaaag aaggacttga
    19021 taaagaaggt gcaaaggctg aattatatga tttagaagat atgacattaa cagaaatgca
    19081 cgatacatta gtagtgtcaa aagtaatatt actaggctct ccaactataa acaaaactat
    19141 ggttaaacct atgtgggatt tattctctgt tatagaccca atggctaacc aaggcaagat
    19201 agcaggagta tttggttcat ttggttggag tggtgaaggt ataactatgg ctgagacttt
    19261 acttaaatct atgtcattca aaatgcctgt agaatctctt aagaaaaaat tcttccctag
    19321 tgaagagaca ttaaaagagt gtatggcatt tggtgcagaa tttgcaaaat tagttaaata
    19381 gccattaatc acacataata ttatttaaaa taaatgattt tatatttaaa aataaattaa
    19441 aaaggagttg tctcaaaatt aatttttcta atctaatttt aagttcaact ccttttttat
    19501 tttctaaaat gactgatata atgataaatg caccctttgt gcgagggtgc attatttata
    19561 atatgttcta tttgtacact agtatatttg tattaattca catatctagc gtatgctacc
    19621 atccctcttc cagaattaga tgccgtttca ccaatttcca ctttaataat tacattattt
    19681 tctttacact tttttgataa ttctgctgca gaaaggttct taccagtaaa atctaaagaa
    19741 aatggcttat catattcaaa aggatactca tcaggtacac catctggagc taatgcaacc
    19801 ataccatatg gtgtattcat aaaccctatt acagtaactg tatgctttga tgggtctaaa
    19861 tttgaatttt tgcttgtaaa cttaattgta tttattgatg agttgattaa actacacgga
    19921 actccctcat acatttcaat ttttggacgt agattatttc cataaacttc atcaagtatt
    19981 gccccttgtt gatctgctat catagtgtga ttcccaggtc caactggcgc agaaggctta
    20041 gctggcgtag gtttcttaac agttggcgtt ggattctgtg tctttactac ttcgccaaca
    20101 gctggatatg ctttcttgtc aaatggtaat gggtgagtaa gactcttgta tatgatgtct
    20161 gctcctgctg atttgttggc atcaatatct acatgataca aacgtccatc ctcaaaacga
    20221 ataagattcc actgatggtc atttgttgta ctatgtacat aataacattc aattcccata
    20281 gcatcacata aagctttcaa gctcctacac attccagaac aagcaccttt tttagtaacc
    20341 aatgtataag cagtattggc tccctctgct gcgttccagt taacatatgt tgtgttgttt
    20401 ttaatgtgat tatgtataga tacaatccac tatggagaaa tataaaagaa aagagtataa
    20461 caaacaataa aaaataagat gattcaaatt ttattttgaa acatcttatt tactctacaa
    20521 attaagatta tttggtgaat tatttaatta ttatttttta ttaaagaaat tttaaatctt
    20581 aatataaaat acgctattat acataataat ccaaatgcaa atgctactgg aattaacatc
    20641 tccgattcaa aataaaagaa atattctaag aaaatatctg gatttactat attcccattc
    20701 ttgtctaaaa aatcttttcc attatatcct aaatgctgta taaaattact tatgttatta
    20761 taatctgctt ccctctcata taccatatta gcattcaatc ctgaagaact taaattagtg
    20821 tttccatctt tcatatctat tacatatagt ctaagagctt tgactttact atacttatct
    20881 ttatcaagta ttttttcaag ttctaactta tattcaccaa tctttgtcat atcatgtctt
    20941 tctgccaatt gctttatttc tccatcaagt tcttttccta aattatacat attatgttgt
    21001 aaactattat tgtaatacca cataaatcca gaaattaaaa atgcaattat acttatgtaa
    21061 cctaatactt ttttaaaccc cattacaatt gatttatgcc tatccaatga taaagatagt
    21121 tcttttatta tattacataa ttcatactgc atttcatcac catcatcaaa tctttcaatt
    21181 gcttttttac atgcttcttc ttcatctaat ccttctaatt taaattcatt tgcagattct
    21241 ataagatggc atctcatttc ctgttttaat tctatagtac ttttattgtc acatttttta
    21301 tatagtttat ctaaatattc atctattagt ttcataaatt aatccacctc tcccaaaaat
    21361 tgattcataa cctttttaat aaatctccat tcttgtttct ttatttctaa aaaatcttta
    21421 ccttcattag ttaaattata atattttctt cttccacctg aactttgttc attgctataa
    21481 taagatttaa ttaaattttt agattccatt cttttaagtg caagatacat tgttccttct
    21541 tttaattcaa actcacttct ttctcttact tgctttgcaa tttcatatcc ataacaatct
    21601 ttcttttcta atatagaaac aattaatata tcgatataac cttttaacac ttctttattt
    21661 aactgcatta tgtaccaccg ccttttcacc tactactcta taatgtatag tacttatatt
    21721 tactataata ttacatagta ctctataatg caaggtttat attctaaaat agactcaaaa
    21781 ataataaata gctgtatatt aatatttaat ctataaatac taatatacag ctatttatca
    21841 aattttaaaa ataaattttt gttttattaa tgttgtcata acaacattta cttgattgaa
    21901 atagtattac ctataagttt aaatatatat aataatagac ttgattctat ttcatattat
    21961 taaaatagag taatagttaa attctactac tctatctata atctatttcc taattattta
    22021 atctcaaatt tagctcttca tcatttaaat ctttcataag atttctacag gtactaggtt
    22081 tattccaaca gaaagactag ggcattaaac acttatatat ctgtttcttt agactgtaat
    22141 attaatattt tttaaatacg ttgacttttg ctttttctaa cttctctcca tgatagttct
    22201 cctctatcaa gagcttttat aaatatttct gctgaagcta gatttgtagc tattggaaca
    22261 tgataaacat cacaaagtct tattaacgct tgtatatctg tttcatgagc ctgagatgtc
    22321 aatgggtctc ttaaaaaaat aactaaatct atttcttgtg ttactattaa agaacctatt
    22381 tgttggtctc cacctaaagg accagatgct aatctattta tatttaattc agtttcatcc
    22441 attattcttt ttcctgtagt tccagttgca tatagtccat acttttttaa aattgattca
    22501 taacctatac aaaatccgac catagtgttt ttcatttggt catgtgctac taatgctata
    22561 ttcatatatc taatctcctc aatttatgtt tagatgtatt taaatttaga aatttatttt
    22621 ctttcttctc atacacacat ttagtactaa tcctaagttt gctaaagatg tcaataacga
    22681 acttcctcca taacttacaa aaggtaatgt tactccagtt actggtatta acgcaaccgt
    22741 catacctata ttttggatta tctggtaacc aaacattccc ataacaccaa ccactatgag
    22801 ggttccataa aaatcttttg catctcttgc aattgctaaa agccttaata ggaatatcat
    22861 aaataagatt atcaacactg ccattcctat tacaccaagt tcttcaccta caacagcaaa
    22921 tataaaatca ctatcttgta caggtaaaaa atcttcttga ttttgacttc cattgtaaag
    22981 tcctttacca gttacgcctc cagaaccaat tgcaatcaga gattgcataa cttgatagtt
    23041 tccttttaga gttacatctt ctggatttag aaaagcttct attcttacct tttgatggtc
    23101 tgccatcatt aaatacatca gtggcattga cactaatagt atgattattc ctctttttat
    23161 caactttgag ctaagacctg ctgtgaacag cattgcaaat atcatacaac aaaatacaat
    23221 tcctgttccc aagtctggtt gtgcaatcaa taatccgata aatggaagag aataaactac
    23281 aacaggcata acttccttta acgtatttaa tttatccttt ttggattcaa gtatctttgc
    23341 ataacttagt acaaatgtta atttgactat ttcagatgtc tgcaagtcaa gtggtcctaa
    23401 gttaatccac gacctagctc caccttttac tgtcccaatt ccaggtaata aaactatggc
    23461 taacaaaata agacttatta tataaagcgc tttataatac ctgcctagaa ggttatagtc
    23521 aaaaaataat atgactataa tcattcctat cccaagtaca aaagctaatc cttgtttaat
    23581 caattgatta tatgaacctg ttgaattagc atgtgttgca ctactaagta taacaagccc
    23641 aaaaataaag atagctaata ctgtaactat aagtttccag tctaactgtt ttatcaactt
    23701 aattgtcgac ttataattaa tattgatttt tttcaaagaa tcaccgtctt tctatcttta
    23761 aacatataat taaataaaag gggcatatac caataaggat atcccccttt taagcactaa
    23821 ttacatacat ctatctttta tattctttag tggtatatta gcaactaatg cagatacagg
    23881 tttgtcatca tgctcacctc tgcatttaga catttttatt tcaagaccat catcttctat
    23941 ttctgcataa ttagctatta ctttcaaaat gtctgttttt atcatctcta aaagttgtgg
    24001 tgaacaatct actctatcat gaactaaaac tagctttaac ctctctttag caacagattt
    24061 actagtttta gcctcgttag aaaaaactct aaataaatct aacacagatg tatcctcctt
    24121 tgctacttag ccatgctaaa cattttttta agtctaccaa agaatccatc ttcaacttca
    24181 agatcaagta gaggaacttc ttcatttagt atcctttttg cgatattttt gtatgcttga
    24241 ccagcaagtg acttagaatc aagtatagct ggctctcctt tatttgttga tataattatg
    24301 ctttcatcat caggaacaag acctaacaaa tctattgcta atatttctat tatatcttgt
    24361 ttatccatca tgtctccacg cttaaccata tcatttctaa ttctatttat aactaatctt
    24421 atctctttta tttcatttgc ttctaataga cctattattc tatcagcatc tcttactgct
    24481 gatatttctg gattagtaac tacaatagct ctatctgctc cagctactgc atttttaaag
    24541 ccttgctcaa tacctgctgg acagtctatt attatatact cgaaagattc ttttagtttc
    24601 tcacacaggt caatcatctg ctcaactgag acagcatttt tatctctagt ttgtgctgct
    24661 ggtaataaat atagattatc aaatcttttg tcttttatta gagcttgctt aagcctacaa
    24721 gttccttcaa ctacatctac tatgtcataa actattcgat tttcaagacc cattactaca
    24781 tctaagtttc taagtccaat atctgcatcc acaactactg tttttttatt ttctaggctt
    24841 agcgcagttc ctaagtttgc tgcggtagta gtttttccaa ccccaccttt accagatgtt
    24901 ataactataa cttcgctcat aatactaccc cctatttttc tttctatttg tctaactttg
    24961 acaaatagct ttcgattaca attcttccat tacttacaaa ggctatttct gggctaattt
    25021 ctgattcact ttcataattt tcttcatcat ctggagcttc tgcaatatta tctgctattt
    25081 gtaatatttt aggattaaga tttccagcaa caacatatgc aaattcattg ccttctgcac
    25141 ctgcatgtac aaaaccttct attttaccca ttacaaaaac attacctcct gctacaacct
    25201 tagcaccagc atttatatct cccataacaa ctgtatttga ttttgaaagg acttttgaac
    25261 caggtttcat atcattcaat ataactacat caccttcaaa ttcaatattt tcaccagatc
    25321 ttagggtatt gacatatttt gttggaaaat tactattttc ttcaattttt tgatcttcaa
    25381 caaattccac atcaaatcta gaagtaattc cttctttaag ttctagaatc tccatgtcag
    25441 ttaaacaatc actattaatt ttactaattt tagccccatt aaaaaagcca acatatgctt
    25501 ccaatttgtt tattattttt tcctgtattt cctcaaatgg agcttctctt tttatattta
    25561 ctattatccc tcttttatta cccttgaact ctactagttc ttgactacaa atttctctta
    25621 aagacataac aacctccaga gtgatatatc atttatattc ttcaaatacg ctttaaaccc
    25681 ttttattttt tctatataaa gctaaagttt atacatagat tgagctatct attaatttgt
    25741 gactcgaaat ttatattttc gtcagaagaa ttgttaacat cattcgtctt gttgtcattt
    25801 ttactattag ttggctctaa tcccatataa gttccaataa cttctctagt tggtaaaagt
    25861 gagaatacac ttgaatcacc ttgaggaatt acacatacaa cagctatttc tgggtcatct
    25921 gctggagcaa aagcaacagt ccacgtaaaa gaaccataat cttgtttaaa tctatctatt
    25981 tggtcatctg ttatttttgg atttaattct tttatagctt ttcttagata tgaagaattc
    26041 accttatcag tgtcctctaa tctaactttt actccatctt ctaattcttc ctctaatttc
    26101 tttctttctt cgtctttcaa atctttattt tctaatttct tttttatttc cttttcctta
    26161 gctaatgaaa gctctttttc tttttctgct ttcatcttat cagctagttt aatcgcatca
    26221 tttaggttga cattataaga tgacatatga ctttttaaat attcatactc gttatctgta
    26281 ggtattttcc cacttttctc agctgtacca gtttttgctg ctacatctat tggcaaatca
    26341 gcaaaagcac tcttcgctgt accttgtctt acaaccaatt tcataccttt tgttaattct
    26401 tttaagttat ctggattttt aaaaggtatt ttttcgactt tcttctggtc attaatttta
    26461 actgatgaat aatcacttga aacagctcta tcaactacag ataattctac taaattacct
    26521 ccatttgcta tagcagctac atatcttgat atttgagctg gtgtataagc attttcacct
    26581 tgacctatag ctaagttaaa tgtatctgca gtactccatt ttgtaaagtt aaaataacta
    26641 aatactgcta aatctgctac ttcttcaatt ctatcttctt taacatccaa tttttttagc
    26701 ctattcattg tttcaactct accaggagtt ttcttttctg ctgcccagct tacaatctca
    26761 ttgattcttt tctcatattc tttaggattt ttttctctag ttatatcaac aaaatcattt
    26821 gccatttctc tttctaaatt tgactttaga agagcttgtg ttgatttcaa tttatcttct
    26881 gcgctaggaa ctttacctgc tctttcttct acttcatctt gaagccctgt attttggtca
    26941 agcccaaata attttgcata ctcaagtatt ttatttgcat tcatatctat accaatgctt
    27001 tttccatctg gccatgtttt acctgtacca attgttgcca tatatatatt acaagactct
    27061 tgtattgctt tatataagtt tgtcatacca tggtttcctc taccatggtt ccatacatag
    27121 tcaccaaaag attttttacc taacattata accccagggt catttatagt aaagtttgga
    27181 tccagaccat tttctaacgc tgccattgaa gttagcatct taaatgaaga acctggctga
    27241 aattcccctt gtgtaaccaa gtttaaaagt ggacttcctg ctagtaagtc atttggattt
    27301 tttggttgaa gtgctttata atcctctgta gaaatacctt ttgcaaattt atttgggtca
    27361 taattaggat aacttgatga agctaatact tctccatttt taacatcaat agctataaga
    27421 gctgctgact gtgcttttcc tgcatatgca ctaattggtt tgtccccaaa tttactttta
    27481 aaagtacctc ctttagaagc aacttcgatt atctgtttta atgcattgtc tgaaacttct
    27541 tgtaaatctt tatctagtgt aagatacaca gtatctcctg atttaggttt tttagattca
    27601 atttctttac tgattctacc caatgcatca actttaacca ttttataacc atcagttcct
    27661 cttaatctac tttcattact cttttctact cctgcaagac ctaccatgtc tccagtttca
    27721 taaccttttt gaaggtatga ttctatttga gtggatggca tttttcctac atatcctaac
    27781 atatgagaag ctaatgaccc attaggataa tatcttactg gttctactgc tattgaaaca
    27841 ccaacaaggt ccatagcact ttcttcaatt tgagcaatcg tagtttctcc tacatcctta
    27901 gcaatagtta ctggattata ttgagaatat ccttttgatt ttatcaaatc ccttacgacc
    27961 attatttttc ttgcatcttc atcactcaaa cttttatcaa tttctaatgc atcactattt
    28021 cttacttttt caaacgcttc tttggcactc agtttagttt cttttatctt ataactagcc
    28081 aaccaatctc tcttatctct ttctgctgtg aacatccatt tactaactaa aataggtgga
    28141 taatatccat tttcatttag ttttgcctgt aatcttgtcg catccaatct tttatcttct
    28201 tgagataata ttccagctga tataagttta tccaccaagt aataaaaact ttccttagca
    28261 ttataatcat ttggaatacc attttctgat ttatattccc taatatctct gtcatatgta
    28321 taatagtact ttccattttc tacatatata ggaaactcat ctacatattc ttcaccattt
    28381 ctctccagca aatttataag ttttaatgat atttcatttg ctcttgaatg cttatttgca
    28441 tctttcttat taatatcgtt acctgaaact tgaacagtaa ataagttttt atttcctgcc
    28501 aacagtcttc catatctatc ttttatttct cctcttggag cttctattgc caacttttta
    28561 tatgttttat tctcagctaa ctcattgtaa tattcatatt taaatgtagt catatagatt
    28621 atttttacta aaatagctaa aaatatcacg cccatgacta tcttaattat ttttagtcta
    28681 tcaacttgtt tattttcttc catgaaatca ccaactaatc ttctttaagt tttaaaactg
    28741 ctcttttaga taagcgatat attactaaac caattaaact attcactatt ggtgctacta
    28801 gtagaccttt tacaaaaagt gttgatatgt tgtagctttg ataaattata ctagatgtac
    28861 ctatattgac aattgaatca attaaactgc ctataaaaat taaaacgaaa gtaataatat
    28921 aactaccttt atatagctga tctctcatgt atccaattgc atatgcaata ataaacaaaa
    28981 ttaatgcatt tacaccaaaa attccaccaa cggttatgtc tttaataagc cctattattg
    29041 ctgctataat cccaccttct aattcatcta aataaagaga gattatggtt acatatataa
    29101 gaactaaatt aaagcttatg ccaaaaatat ctatataatt tgttatacta ttttctatag
    29161 tcataagcac aatccccaac agacaaagta aaactttttt cattgttttt atccccttta
    29221 tcctatattt cttggttcta tgactacaac gtcatttata ttcttaaaat caacataagg
    29281 ttttacaact acatatttta atgacttatc tttatcatca accacttttt caacttcgcc
    29341 aattggtata ccatctggga agaatccaag acctgatgtt gttattatat ctccttgaat
    29401 tacattatat gatgagtcaa acatatatcc ttgcaaatat cctttactat tataactatc
    29461 tttattatct aaagtagtat tttgagtaat tgtaccttta gcattggcat cctttgctag
    29521 tttaaagctt acagatgcct tagaatccaa tagtgaaatt gccttactat aattgttgga
    29581 aacctcataa actatgccaa ctaatccact accattcata actatacttt ctttttttac
    29641 acctgaattt tttcctgcac ctatgacaaa actctcatac cagtttccat catttttacc
    29701 aacaacactt gctgaaatac ttgtcgcctt atactcttct tgtacaaagt tcagtgtctt
    29761 ttttaactct tctagcgatt ctgttttatc tagtttggca tttaaagcta tcatattttt
    29821 tttaagtttt tcattttctt cttctaattt ttttaccttt ttagaattat ctttaaaatt
    29881 tgctacatct ttaaaaccat ttttgataaa agaaaatcca tcatttattc ccttacctac
    29941 acttgtaata gcatctgaag ctactcctaa atttactgga ctaccactag aaaatttacc
    30001 aattgatata cccacaattc caattaaagt gatagcaact acgcccgttg ctatcacttt
    30061 aacattaatc ctttttttct catttttgtt cttgtcaaat ctcaaggcca tcaccaactt
    30121 ctaattctta gtattcatca ttaatacttt ttcaaagatt tcttggtctt caacagattt
    30181 acctgttcca agtgcaacac aatcaagagg tgtttctgct atttgtacag acataccagt
    30241 ttcctgtgta ataagcttat caagacctct aagcaaagcg cctcctcctg ttagcattat
    30301 tccgttttcc attatatctg aggctaattc tggtggagtt ctttctagtg tagattttat
    30361 tgcatctact attgaactta caggttcttt taatgcttct ctaacttctg tagagcatat
    30421 ttctattgtt ttaggtaatc ctgagattaa atctctacct cttatttgca tatttatttc
    30481 ttcatcatct ttaaatgtag aacctatgtt aatttttaca ttttcagcag ttctttcacc
    30541 tatcataaga ttatattctt tttttacata agccactata gactcgtcaa attcgtctcc
    30601 acctattctt atagatttag cagtaacgat tcctcctaaa gatattacag ctatttctga
    30661 agtacctcca ccaatatcaa ctaccatatt accttctggt tcttcaactt ttaatccagc
    30721 ccctatagcc gctgccattg gctcttctat aaggaatgca tctttagctc ctgcttgtct
    30781 tgcagcctct tctatagctc tcttttctac ttctgtaact ccaaaaggaa cacatatagc
    30841 tattcttgga cttacaacac cttttttatc agccgctttt tgtataaaat agctaatcat
    30901 tgattgagtt atgtcaaaat cagctattac tccatctttc ataggtctta tagctactat
    30961 atttcctggt gttctaccta tcattttttt ggcttcttca cctactgcta atacctcttt
    31021 actatcatct cttattgcga caactgatgg ttctctaaca acaatacctt gtccttttat
    31081 gtaaactaat gtatttgcag tccctaaatc tattcccata tcctttgtca tcttattaaa
    31141 actaaaaaaa cctttttttt ctttcttttt ttccttagcc atgattttac tccttcctac
    31201 tattaagaat catgtttaaa acattctcct attattttat cacatataaa gtcaaattat
    31261 catattttct ttaaagctaa agtataatcc atctccaata attatatggt ctattatttc
    31321 tattccaatt atttctccac atttaataag tcttgatgtg atatttttat cttctcttga
    31381 tggttctaca cttcctgaag ggtgattatg catcactatt atcttacttg cacttcttct
    31441 tatagcttct ttaaaaacct ctcttggatg gactaatgac gagcttaaag tccctataga
    31501 tacatctaca tcagatatta tctcattttt tgtgtttaaa agaaccgctt taaaaacctc
    31561 tttttttaaa taccttaggc tatccatata atacctctgt atatcccaag gattccttat
    31621 tttatacttt ataggtttaa aactagctac tctagagcct agttctaaag ctgctttaat
    31681 ttgggttgat tttgataacc caattccatc tatattacac agctcctcta ttgtcatatc
    31741 ttctaaatgt ctaataccct gaatatctct atttattata tagttggcta attcaatagc
    31801 atttttattc ttgttgccag ttcttaaaag tatagccaac aactcagcat ttgataagct
    31861 ttttacgcct ttggcaagca tcttttctct gggtctttcc tctggtgcca tttcttttac
    31921 cttaatggtt gaattaaatg actttttcag ataaatcaca ctccataaaa aagatttata
    31981 ctaaaatatt tttttaatag gtcgcctaac cttgaaattg gaagaccaac tatattaaaa
    32041 taatctcctc taatttcttc aactaacaaa gctccataac cctgtatacc ataggctcct
    32101 gctttgtcaa atgactcatt agttttcaga taatcctcaa tatcctgctc tgataacgtt
    32161 ttaaatttca cattgctgat tacatagtca attacctttt tatcttcgca caagtttatt
    32221 aagctaatac ctgttatgac ttgatgctct cttccagata gtctttttaa catatctctt
    32281 gcacaagact catcttttgg ttttcctaaa atagcattgt ctaaaacaac aactgtatca
    32341 gctccaataa caacatcttc attatgttca gatgctacag acatactttt ttcaaaagct
    32401 aatctcataa ctaaatgttt tggtgtttca ccttccaata taatctcatc aatttcattt
    32461 ttaattatat caaatcttac attcgtattc tctagaattt ctttccttct tggagaggct
    32521 gatgccaaga ttatattcat ttattcacct catttgtacg taatttgtac ctatttagtc
    32581 tatcactatt tgtacctatt tagtctatca ctatattgta aaaaattcaa cagaaatgtc
    32641 gaaccttttt tgttacacta ttgttatatt tattaccatt agaataaata tacataaaat
    32701 agaggtatgg aaattattcc atacctctgt tttatgtact cattagagat atggaaatta
    32761 ttccatatcc ttattttgtc catattacaa aattttaata gctttctttg gacatttttc
    32821 catacataaa tggcatccta cacatttatc tgcatctacc ttatgttttt cttttaattc
    32881 tccctctatt gcatcaaact tacattgttt tttgcacact gtacatccaa cacaaagttc
    32941 ttggtcaata gtaactttct ttttcttagt tatgtcacct gatattactt ttgtagggca
    33001 ttttgctaca cattgcatac aacctacaca cttattaggg tctatcttag ctattttgtc
    33061 ttcaaatatt attgcatcaa atttacaagc ttttacacac attccacagc caatacatcc
    33121 agcagtacat ttttctttaa cagctttacc aaactctttg ctattacact ctacaactac
    33181 ttcttgactt tctggttttg tgattattat acccttagga caaacttctt tacattttcc
    33241 acaatttaca cacttttctt catctattac tgctattcca tcaactatag aaatagcatc
    33301 aaatttacaa gcatctttac atgttccaag acctaaacat ccaaatttac acatcttagc
    33361 acctgagttt aaaacatttg ctgctctaca atctgatatt ccttcatact catatttatc
    33421 ttttgcactt gaacaagttc ctttacaaat aacttttgct acttgtttct cacctgcttc
    33481 agcacttatt cccattattt ctccaacttt tgcaccaaca tctgctccac ctacagggca
    33541 accattaact ggtgcattgc cttcaactat cgcatttgca agacctccac aacctggaaa
    33601 tccacaacct ccacagttgg ctcctggaag tactcctagt atagcttcca ctctctcgtc
    33661 tacttctaca gcaaactttt tagatgcaaa atctagtact atcccgaaga ttaagcccat
    33721 aattcctaaa actaatacag ctgtaagtat caccattttc acccctcttt tttatagctt
    33781 tataagtcct gtaaatccta agaaagctat tgacattaaa cctgctgata taagcgttat
    33841 agggaaacct ttaaatgctt ctggtatatc agctaattct agtctttctc ttatacctgc
    33901 gaatattact attgctaaag taaatccagc tccggctcca aatccgttta ttattgtttc
    33961 tactaaatta taactttttt gaacattaac tagagctata ccaagaactg cacagtttgt
    34021 agttataaga ggtaaataaa ctcctaatgc ttgatataaa gatggactca tcttttgaat
    34081 taccatttca acgaactgaa ctatagaagc tataaccaat ataaaagcta ttgtttgtaa
    34141 gaatccagtt ccagttttta ctaataaaat ctgtataaaa taagttataa ttgaagctag
    34201 agttaaaacg aatgtaactg caactcccat ccctactgct gtatcaacct tcttagaaac
    34261 tcccaagaaa ggacatatac ccaagaattg agatgttata acgttattaa caagaacgat
    34321 acttaaaaat aaaagtatta aattcattta ttacacctcc actatgcttt tttacttctt
    34381 aatttattaa atcctgcaaa taagaatcct aatgttaaga atgcacctgg tggtaatata
    34441 aatattaata ctggttggaa agatgctcca aataatgtca ttccaaataa actaccattt
    34501 ccaagtaatt ctcttactgc acctattatt gtaagtgcaa cagtaaatcc aagaccttga
    34561 cctacaccat caactattga aggcatagct cctgttttga aagcaaaact ttctgcacga
    34621 gctaatatta aacagttaac aactattaat ggtatatata taccaagagc cttatcaaga
    34681 gcaggaacat atgcttttaa aagcatacct actattgtaa caaatgtagc tataactact
    34741 ataaatatag gtattcttat cttatctggt gtaatttttc ttattaaaga tataactaaa
    34801 tttgcacata ttaaaactgc tgctgttgaa agacccatac caattccatt tattgctgaa
    34861 gttgtaacgg ctagtgttgg acacatacct ataacttgaa caaatgttgg gttctcatct
    34921 attagcccat ttttaaatac tttagctaaa ttcataatta accctcctta tttattaaga
    34981 gcactattga aaacatctat agcagcattt actcctgtag taactgctgt agatgtaata
    35041 gttgcacctg atattgctaa tatttgatta tctgctgttg tacttccttt tgctacttca
    35101 agaggctcag cagtttttcc tttgtattga cccttaaatg catcatcctt agcttttgct
    35161 ccaagacctg ctgtttctga catattacca atgtcaacac ctgtaacttg accttcagat
    35221 gatataccta ccataacttc aatttctcca ccatatccac ttggtttagc ttttaaagta
    35281 tatccaacca cttcagaacc atctaaacct tcatacactt cagctataag accatctcca
    35341 aggcctttgt aagtatcttc cttcatttct ttaaattctt ttgcttctgg aaggactgct
    35401 tttctaagtt cattatttgc ttgtatattt ctttgttcta ttactggagc tgtaacctga
    35461 ttagtagctc caagagctaa tgcagctatt gcacttatag caagtaaagt accacctaat
    35521 ctcaccatac tgttcattat ttagccacct ccccaaatac tctatttcta acaaacttat
    35581 ctataagtgg agcaagacag ttcactaata gtattgagta agatacacct tctggatatc
    35641 caccatacat tcttataaca gttgttataa gaccagctaa tacagcgtat attatttgac
    35701 cttttttagt cataggcgaa gttgtataat ccgtaagcat gaagaatcca cctaacataa
    35761 gtcctccagc aaacagttga tatattgcga aagttatatt aaatccacct aaaaggaatg
    35821 ttaatataaa tacagttgct atgtaaaata ctggtataac ataatttatt atgcctttat
    35881 acattaggta tactccacct aataataata atattgctga tgtctcacct atacatccac
    35941 caatattccc tatcatcatg tcagcaagac taattccatt gctagaaagg tctgccagtc
    36001 ctgctgctcc atttttcaaa aagcttaatg gagttgctgt agtaactgca tctaaatttt
    36061 tacctatcca gttaacacct ggttgagtcc aagcagtcat tgctactggg aatgatgcta
    36121 ataaaaatgc tcttgcagca agtgctggat tgacaaagtt acatccaatt ccaccaaata
    36181 ccattttaac tactaatatt gcaaatattc ctcctactag acacatccac caaggaagtg
    36241 atgctggtac gttaaatgct aataataatc ctgttacaac agctgaaaaa tctcctatag
    36301 tacttttttg cttcgtaaat ttttgatata aaaattcagt acctactgta ccaagtatac
    36361 aaaaaaacat agcactcaaa gcattaagtc taaagaagta tactcctgct actgctgctg
    36421 gaaggagtgc tataataact tgtttcatta tatatgaagt atcttcatta cttctcacat
    36481 gaggagaaga tgatactatc aacttatttt ccatcgtttt tcccccttaa ctttctttat
    36541 ttctgagcag cttgctttct tctctttgct cctatttctc tctttgctga tcttatagat
    36601 tgaagtaatg gtcttcttgc tggacaaata aatgagcaag acccacattc tatacaatcc
    36661 attgctctat gatattcagc tgtgtcatag tcatctttta aagaatatgc acttatgaaa
    36721 agtggttgta agaatgatgg acatacatct gtacatcttc cacatcttaa acagttttga
    36781 atatctggag tacgtgattc ttcctcatcc aaacataaaa ttcctgaaga acctttgtta
    36841 gtcgctattt cagtagtata ttgagctatt cccatcatag gtccacccat tataacctta
    36901 ccaatcttct tatcttcttt aaatccacca cattgttcta ttatttctga aactaatgtt
    36961 ccaacttttg ttattaggtt ctttggctct ttgatgcaac tacctgttat tgtagtgatt
    37021 ctttcaacca aaggcatacc tgttttaata gacttagcta tctgtgctgc tgtggcaacg
    37081 ttgtcaacaa ctgcacctgc tgctattggt aatccaccag atggaacttc tttgcctgta
    37141 cacgcataaa taagttgttt ctctgctcct tgtggatatt tcacttgaag gccaacaact
    37201 tcgatttcgc tatagtcttt agctacattt tgaattgctt ctatagcatc tggtttattc
    37261 gtttcaattc ctataaatcc ttttttgaca tctaatacct tcattaatgc tcttaaacca
    37321 aacacaacat cttctggatt ttcaaccatt aatctgtggt ctgcagttaa gtatggttca
    37381 cattctgcac catttaatat aactacttct gccttgctat ctggtggagg agatactttt
    37441 acatggttag ggaatgtagc tccacccata cctactattc ctgcctcttt tatgatacct
    37501 actatatctt ctttgctcaa atcctctaac tgaccttttg gttgaacact ctcatgtaat
    37561 tcttccttaa agtcattttc gataactaca cattgagctg aacctcctgg tacttcatgt
    37621 tgttcaatag caataacttt acctgatact gaagaatgaa cgttacatga aacaaaacct
    37681 tgttgttcac ctattttttg cccaaacttt acttcatcac caacttcaac aataggttta
    37741 gctggtgccc ctatatgttg ctgaagagga atgtaaacta tctttggagc ttgagctttt
    37801 tcaagtgcct ttgtgttaga gtactctttt ctatatggag gatgtatccc tcccttaaaa
    37861 gttaagagtt tcattgtttt acccccttat ctataaaaaa acattttttc tgccttctat
    37921 aagtatacta tatatattaa aaaatcttaa caattgttaa aaaaatatcc gtatttttat
    37981 aatttatttt ataaatcaat acctctatat taagtcaaac cgaggaaaag gattgcttaa
    38041 ttaaacaatc cttttcatat agctttctaa agtccaaatt ttctgtattt tattttatag
    38101 aatttataaa catagagtac tcctgcatgg atgataaaag cagactttta cttacactat
    38161 atttttcttc atttgctgct tttgaagctg tatcaatttt ttcattcaca ttctttacat
    38221 actctattaa attatcttta aataaacgca tttcagaata gtcaatcttt tcagcttctt
    38281 ttgatatatt ttgtgatatt gcctttctat ttgtcaaaat agtattatat ttttccatat
    38341 ctacattatt ttcagcattc gaccaaaaac ttgattcttc tttaaagttt gttattaatt
    38401 tatttaattc tttagatata ctctctatat aagcgtagtt acttgtatac tctaaagaca
    38461 acataggtgc atctaagtgt gataaaaatg catctggaaa cacctttctt acactgctta
    38521 tctgctttct aacatcattt tcatcaaaag aggaataggt ctgtattttt tttactccat
    38581 ccttctccat aactgaaaaa ggtatgtcat tattaactaa tgatgtctgt atttttttca
    38641 aatcatcatt attatctatt gcagcaactt gaatagtata catatcccag ccttctatag
    38701 tagctaattt gacttcttct ggctctttag tgttatttac cgctttttct ggattagttt
    38761 cttgtttatc atctgaattg gtttgtgatt tagatttttt cccttttttt attgaattta
    38821 attcatcaga tatatcttta taagttatat ctgatgaatt atttagaaat ggtattttag
    38881 ccgatacata ctccaatatc ttgctatctt ttatttttgt ataagaataa tagccaatta
    38941 gacacaagca agcaatcgtt ataacatatt tacgtaaatc aatcttatgt ctattattat
    39001 taaatcctct gtatatcgtt tttcttctat tcattagttt gtccctccca aaattatatt
    39061 attaataaag tatattttta agagtcacaa tttatgaata taaataatta tttcttctaa
    39121 ttttttaata agaaattgta cttactaaac aaatcttctt gcaccaagta atactttaga
    39181 ccaatatgaa ctagttaaat tatctacttt aaccttatta ggattagtct gagtaccact
    39241 acaatggata aatttactat ttcctacata tatacctaca tgattagttg ttccatcacc
    39301 atcagtgtca aaataaacta aatctcctgg tgcataattc cccatagaaa ttgcacttcc
    39361 aaaattagcc tgttctctag aaactctagg aatagaaacg cctacagaat gtttaaaaac
    39421 atactgtgta aatccagaac agtcaaattt atcaggccct gaagctcccc attgatatgg
    39481 tattccaata agagtatatg caaaatctac gattgttgaa ccttttgctg tagatttatc
    39541 tgaatttcca gtaaatgatg gctttgagtt actattagat tgagaatttt ggttagatga
    39601 tgaatttggt ttttcttttg tatcctcatt agtctcagaa atataactgg cactcaccca
    39661 tccaattgtt ccactcgata actttacctt ataccaacca ttacttttag cttttaattc
    39721 aacaacatct ccaccattta attttcctat tatagaatag cttgtcccag gaccacttct
    39781 tacatttaaa ctcacagcag atgttacctt accattcttt ccttcaattg attcttcgct
    39841 agatggtttt ttatcagaat tattagtact atttgaatta ctagaattgt tcgttccaac
    39901 atcctctgat gttttagaga tatattggct actagcccat ccagtaactc catttgatag
    39961 ttttatttta taccatccat tgctttgttc tagtaacttt actacatctc cattatttgc
    40021 tttaccaact aatgaatagt tagtacctgc accacttctt acattcagtc tagaactcac
    40081 atttacttta ccatttccac taatagttgt cccacttgaa gttgaattat tttgacttga
    40141 tgtaccttca gacgaaccac ttgttgatat gtattttgca cttccccatc caacaacaga
    40201 actcgatacc cttactttat accatccatt agacttttct aaaatctcta cagtttttcc
    40261 cttgtataat tttgctacct tatcgcaatc agaacttggt ccacttctta tattcaaggc
    40321 acttgctgtt actgttccct tttcaagagc acttgcattt atggagctaa cagatactgc
    40381 tactgcccca attcctaaag ctgctatagc ttttttcact actatcactc cccccaacaa
    40441 atttttatag tcataaattc ataacattat tatccatttt tagtccctac aatttaatga
    40501 taacttattt tcttattaat tgtaaagaaa ttataaacat atccttaaaa ttagtgattt
    40561 ttaggaagta tttcaatcca ataattatct gggtccgcta taaaataaat tcccatactt
    40621 tcattttcaa aacatatgca atctaaatct ttatgaagtt tttttgcctc atcaaactcc
    40681 tcaacttcta aagccagatg aaattcattg tctcctaaat tatatggtct atcccaatct
    40741 ctaagccaag ttaattctaa tgtatgacta gtaatgccat ctcctaaata aactaatata
    40801 aaacttccat cttctgcttc cttgcgcttt acctctttaa gccctaaagc ttttttataa
    40861 aaatctaaac ttttttctaa attagtaaca ttgaaattgt tatgacaaaa attaaacttc
    40921 attttgaaat cactctccaa tttttatttt ttttatatta tatcattatt ataaatttat
    40981 ttaaatcata ttaagttaaa aatttgaatg atgatgacca attaccaaat catggtaaat
    41041 tatttaaaag aatatgtcaa aaaaagaata agctctttca aatgcataaa aaatttatac
    41101 ccaagttata cttaatcatg caaattggca gaacttattc tttaaaactc taacttttaa
    41161 gtttttcttt aataatataa tttattactt tttttctaat atcttcagca ttataatcat
    41221 cttctacttc tatatccaaa agttttgcta ttgacctcat atcttctcta gtctttgacc
    41281 tatagcttga tattaattca tcttttattt tctctggttc taaaagatat tcttcatctc
    41341 ctcttttgaa aacaacgtat ttttgagcat atgaacttct attgtagtat atatatcttg
    41401 atatttttct taaaatttga ttatatgaaa gtcgcttgtt aatatcaagt tttaagtact
    41461 ctgaaaaagc aaatagctct ttttttgatt taaataatgc ttctttcttt atagtccttg
    41521 atattgaagt tacactttct tgatatgcac acttttttaa catttttaaa tatactctat
    41581 taagaccaat actttgattg aattttttta tattattatt aataatctta tccaagttac
    41641 cttcaaagta tttttttgct cctttttgtg atacataact ctcaagttct ttgtgggcca
    41701 tatcaagtat catttttttt aaatcctctt tatatcccct agattccatg atactccctc
    41761 ccttagctat ttatagtata ttcaaaaagc tcaagaaatg tgagtcatta caaaattttt
    41821 ttacttttta tgtatatatt aatttaaaag gggagataat agtaatgtaa aatcaaacat
    41881 actcaatctc ccccattttt agacctctat tactccccca atagaggtct ttttttagtt
    41941 tatcaatttc tattcaattc cctttagttc aaatcctaat tctgctatca cttcttttaa
    42001 tttttcaata gatacatcat ctttcatatc tacagatgca cacttatttt ctaaatctac
    42061 atctaaaact tcaataccat ctatatcttc tgttaatgca gttttaagat ggtttacaca
    42121 atgaccacaa ctcatacctt ctactaatag tttcttcttc atttaattac ctccttatac
    42181 cctataaggg tattctatca tatagtttat actttttaaa tagaaattaa tcatttaatt
    42241 tgattcattc gattttatat ctaaattaga tattccctca tatacatcaa aatcatttgg
    42301 agtaatttta ccttttaatc tactattact tacaatatag ttgtttctca cagctaaact
    42361 tataaatgtt gcattatctt ttatatatgt ctgtacatct ttgtatgctt tttttgtttc
    42421 aatttcagac gtagaacttg taagtgcaga catatatcca tttaacttat catcagtata
    42481 tccactactc gctataatac tacttgcatc tggtataatt gatagtttcc atccaactaa
    42541 tgctaaatca taatttttag aattaagagc attttccata tccttatctg acagctgatt
    42601 tactgtacta tttattccta tagcttttaa gttttcattt attatgtttg cagtttttat
    42661 tctctcacta ttatctctgt ttactattat ctttaagttc atttcagaaa gacttttctt
    42721 tacttcctct ttttctctat tttttttctc ttcagcttct tttttgattc tatcttcttc
    42781 tgctttttta gcttttgctt cttcttctgg cgtaagcttc tttgagttct ttttagctga
    42841 ttttttctga ttttttactt tattgtcatt ttgatttact gagtttacat ttgcatattc
    42901 taccttagca agacactcta tcgccttatc tttattaaac tctaaatcct tcatttcact
    42961 attatagtat tttgattttg aattaagtgg aaaattaact ggagtagcat catccatata
    43021 accttcacta ataattctat ctttatctat agagtgtgca attgcttttc taaaattaac
    43081 atctttgaaa aaaggattat tataattaaa taatacacac tcataatctc ttccttgata
    43141 ttttgttata ttaaactctt tttcttgaaa cttacttaaa tcatttaatg taacattggt
    43201 tatatcacta tcaagagcca taaccataga tgtccttgca tcttcattag gcaccatacc
    43261 tacttttatg ttcttcatgg tttttggaac ttcttcatag taatctttgt ttacagataa
    43321 aaccattcct tctctttctg tatatgattc tattttatat ttcccatttc ctatcatatt
    43381 attattcttg tcatttacat cttttgaatc taaatgattt tgagatacaa ttggaaaaat
    43441 taaactatca attgaaaaag catatctagc tttaaatttt attgtaaagt ctttatctga
    43501 tttaatattc acagaagcta tatttttagt aaattcatta tatggactat ctgcactttt
    43561 ttgaattaaa ccaatagtat agtttacatc atttgaagta acattttttc catcatgcca
    43621 ctttgcatct tttagcttta tatctatact cattccatcc tgagctatat tatactcctt
    43681 aactaattga ggaattacat tgtagttctc atctatagta aataaactat cataaactaa
    43741 attcattata taaccaacag acttatcagt attagttata ggatttatag tttttggagt
    43801 taccattgtt aagtttatat acttagcatc tatagaactt tgactttgta aacttgaatc
    43861 actactactt tgttttgttt tagtattact acaaccagct accataagag ttatagctaa
    43921 aacgactgtt aagactttta ttctcttcat tagttttttc ctttcttgcc atatatctta
    43981 ttataatgtt cgtaattatt ttttactttt tctacatatt ttgaagtttg cttaaaaggt
    44041 atatcatgta gattttcgcc atctttacta tattcattat tttctaacca ttttttcaca
    44101 ttacctgaac caccattata tgcagctatc actaaatcta atttaccaaa ttctttgtat
    44161 aacttactta aataccaaca gccaagtctt atattagtct ctgggtcgaa aatatccaca
    44221 ttttttaaat ttagttcctc tgctccccaa tctctagtta tgtctaatat ttgcattaat
    44281 ccttttgctt ccttttttga aacagcagaa ctattaaact tactttcggc tttaataaca
    44341 ctgtaaacta tattttcatc taaattaaat tctttcgaat acttttctac atactctgaa
    44401 tattttttag gatataaaaa tttatgtatt actttgcttt ccattaatag tgccccaaat
    44461 aagattataa aaatagatag aatcaatact ttcttactat tcacgccaat tctccttcat
    44521 gtactcaata aatttatgtg ctttactttc taattcagtt attgttcccg aattatctat
    44581 tatataatca ccatatttgg atttttcttc ctgactcatc tgtgaattta tcctactaag
    44641 tgcttcctgc tcactgcaat tatctctctt ttgtattcta ctaatttgta cttcttgttt
    44701 acaagtaact actaatagct tgtcaaccat atctaaaaaa ccactttcta ccaatattgc
    44761 cgcatctaac actactatat tttcgccttt ttttctcaat ttttctattt cacttattat
    44821 tttttctctt attcgtggat gagtcaagtt atttaattcc ttaagttttt cttcatcact
    44881 aaaaactatt ttcccaagag cttttctatt tagagttcca tcatcatttt ttatactttg
    44941 cccaaaatgg acaaatattt tttccaataa caacttatcc tcaaatatct tcctggatat
    45001 aatatcagca tccactatag gaatgttaag atttctaaat atatttgata ggctgctttt
    45061 tccacagcct attcctcctg taagtcctaa tatcaacata aaatcaccta ctttgtctca
    45121 taccaagaac tacctacatt taaatctaca tctaagtgaa catccatatt tacagcattt
    45181 tccatttctt cttttactat tttcttaact atatctattt catcatcaat tgcttcaact
    45241 atcaactcgt cgtgaacttg tagtataagt tttgatttca aattgttctc ttccaatttt
    45301 ttatgaacat ttatcatagc aatttttatt atatctgctg cacttccttg tattggtgca
    45361 ttcattgcaa atctctttcc tctatttctt tccataaaat tgcttgactt tatttctggt
    45421 atatatcttc ttctgtttaa aattgttaca gcatatccat cctcactagc cttttctact
    45481 gttgtgtcca taaactcttt tattttatgg tatttagcaa aataactttc gatatattct
    45541 ttcgcctttg gaacaggtat atttaaatca tcagctagac caaagtcact tttaccatat
    45601 ataataccaa agtttacagc tttagctgca cctctcaatt cactagtaac atcttccata
    45661 ggaacattaa aaacttgtga agctgttttg gtatgaatat cttcatgatg tttaaatgct
    45721 tctatcatat tttcatcctg actcatatgt gcaagaactc ttagctctac ttgtgagtaa
    45781 tcggcatcaa ccaacttaca gttatcatct gcaataaaca cttttcttat ttttctaccc
    45841 atttccattt ttataggtat attttgaaga tttggttctg tagatgaaat tcttcctgta
    45901 gtcgttatag tttgattaaa tgatgaatgt attctattac tttctggatt tattatattt
    45961 aaaagtcctt caacgtaagt agaatttaac tttactattt gtctatactc agttatctta
    46021 tctattattg gatgcttatc tcttaatttt tctaaaacat ctgcattagt tgaatatcca
    46081 gttttagttt ttttaattat tggaagctct aatttttcaa ataatataac acccaattgt
    46141 tttggtgaat ttatattgaa tggctctcct gataattcat aaatttcctt ttctaatgta
    46201 gctattattt ctttaaattc aacactcaat tcatccaata tacttttgtc tacttttata
    46261 ccttcatact ccatatgacc taagacttct actaaaggca tctctacatg ataaaaaaga
    46321 ccatccatac tcatatccat tagacttctt tccatcatag gaactgtttc tttaactgtg
    46381 catattattt gacccatata ctctgctaaa tcctcaaatt ctaaatcctc atagttttta
    46441 gatttaacac cctttcctaa taattcttct tttgatttaa ccttttttga taaatacttc
    46501 atagctattg cactacaatc atatgaggta gatgaagttg aatctattaa gtactcagct
    46561 attgttatat caaaatacat attttctaag tttatattat atggttttaa agatatataa
    46621 tcatctttta aattatatcc atacttttta atttcattat ttgaaaatat actatctaac
    46681 tttgacactt catttgaatc tacataatat attttttctc catctacact tataaaaata
    46741 tatattatat ttttttcaag tatattacct tgtcctctaa cagtttttaa aataacttgt
    46801 ccttttttgt ttacttcatc tataaatttt tctatatctt ttaattttaa tatttctatt
    46861 ttttcttcta cgtgttctgt gtcatctgaa tcgaccaaat caactaatct tgataagaga
    46921 cttgtaaatc caaagtatct aaatttatct aaaagttcat ctttatcata atcgccaaaa
    46981 atcatactat ctaaatccac ttctattggc acatctctta taattgttgc aagtctttta
    47041 ctttgaatag ctatttcttt gttttcctct attttctttt ttacactacc tttaagctta
    47101 tctgtattct ctattagatt ctctatacta gaaaactctt ttataagctt tatacctgtt
    47161 ttttcaccta ttccaggtac tccaggtata ttatcagact tgtctcccat aagacccttt
    47221 aaatcgataa attgtgttgg agtcatctcg tatttttcaa ttacagaatt aaagttgtat
    47281 tcttcaactt ctccaactcc tttttttgtt ataagagtag ttgtattgtc tgaagcaagt
    47341 tgaatagcat ctttgtctcc agttactatg tataccttat atccattttc ttctgctttt
    47401 ttagaaacag tacctataat atcatctgcc tcatagccat ctatttccaa tctatttatt
    47461 ctaaatttat ctaaaaggtc ttttaatggc tgtaattgtt ctgccagttc atctggcatt
    47521 ccctttcttc cagccttata ctctttatat tctaaatgtc taaatgtagg tgcttttctg
    47581 tcaaatgcta cacttatatg tgttggttta tatatatcta tcattttaaa tagcattgtt
    47641 gtaaatccat atattgcatt ggtctttagc ccttctttat tattcatttc tggaagagca
    47701 taaaaagctc tatttattat tgaatttcca tctattataa ttaatttttt ttccaaatta
    47761 tatcactcct aaaaattatc tatttttgta acatatatat tatataccaa tatactgtta
    47821 tttaatattc ccataataat aatagtatat taaaattaaa tatgttgcaa acaatatatt
    47881 tttttgctat aataatatac atgacatgcc cgagtggtgg aattggtaga cgcagtggac
    47941 tcaaaatcca ccggactaat actccgtgcc ggttcgagtc cggcctcggg caccattaaa
    48001 aactcctaaa gctatttatt caatagatta ggagtttttt tatttttgat ttaaatttta
    48061 agttattttt tgaaattact gtgtcttttt aaaatttata taattatata aatttatctt
    48121 ctagcattaa tttaaaaact aatttacttt tatataattt tctattttat atcataactt
    48181 attacaacct tttatctaat ttattgtata caacaacact acaaataaat tgaaataaaa
    48241 taagcaatcc aagaacaact aaaacccact tgcttattac cattacagaa aatacactca
    48301 atatagaaac aataaatata agaattacaa gaacatagca catgatttga ttagtgatac
    48361 gtccagcttt atcacgtaac ataattcttc tttcatcatt catctctatc ctttgatttt
    48421 ttatcttttc ttcataatct actgctcttt caggtttact ccaatacata tattgaagaa
    48481 tcatacatac acctggacct aaagcagctc cagataatcc ccaaataaag gcctcaaatg
    48541 aaaactcagt aaatgtagcc aataaaacaa gtaaaattcc acaaataaaa tatataattc
    48601 caacatataa catattcttt ttcattttta ctcctcctca taaataaata tttcttcaat
    48661 actcatatca aagtatctag ctatcttaaa ggctaagatg atagaaggat tatacctacc
    48721 attttctaat gaacctatag tttgtcttga tacttgcaaa atagaagcaa gttcttcttg
    48781 ttttatgcct ctttcttttc ttatttcttc taatctattt ttcacatcta tcccccttta
    48841 atatctcaac tacggaaagt ctactttcca taattataca actatattcc atttatgtaa
    48901 agcttacttt ccatatttac aaaaaaataa cagactattt tcagcctgta attttagaat
    48961 ttcatgttgt ttattaattt taatgttatt tattaattcc atattattta ttaattttaa
    49021 tttggtttct gaattggaat ccaaacttct gtagtataat caggagcatt gatatcgcca
    49081 ttgggataaa gttcaatatc tggtaaatta gcatacacat acccagaact tggtaaccac
    49141 tcagtaataa ttcttttttg caattcctgt attgccagag catttggcat tggagaaaca
    49201 cattcaaata ctgcccatgt gcctgatggt attaagtatt catgagtatc ttctaataca
    49261 ggcttatctg ttggagcagc aatataataa tctaaaccct tactatttgt acacacacta
    49321 actccaagca atccacaagg ttcgttattt attaactctg aaagtttatc aattgttcca
    49381 ttttttatgc atttagccca taacttagga actttctcaa aacactcttc tacaatcatg
    49441 ttcatacttt cttttatacc aacaatacga aaccctttct tttctacaat acgatattgc
    49501 atttctatat ttccttttac ataaatgctt aatgtcatct taggatatgc ttttaaaaca
    49561 acaccctttg ctctagctgc agatggagaa atgttatgta tattttgaaa agctctatta
    49621 aaagatgttg gtgaatcgta accatacttc tcagatagtt ctaaaatttt gatgttactg
    49681 ttctgaagtt caaatgcagc cttagtcata cgtcttcgtc taatatattc agataatggt
    49741 acttctgcaa tatatgaaaa cattctttga aaatgaaagg ttgaacaaca tgcaattttt
    49801 gctgcttctg cataatccac tccactttcg agattttctt caatataagt aatagcttga
    49861 tttaatttat ttatccattc catttgatat tacctccaag caaattatac agtttaataa
    49921 aataatatac ctctctattc atgcacaaaa ttgtaagcat ttaaattcat aagtattttt
    49981 caatcaatac aataaatata aaaattgtat tatacaataa aaaagttcaa taacattata
    50041 ttataaaatg ttattgaact ttttataaaa attaatttaa gtgtagttaa attaagtatt
    50101 acactatctt atatattaca atatcctact atcttatagt cttctggcac tttataatct
    50161 ttgtctggag tacctaaatt ccattttaaa tcaaacatag ttgcacttat tattgttgca
    50221 aaataaagca taactatacc aatgtctatt ttttcttcat ataaattagt atgaccatct
    50281 tttctaacag ctaaaactac agtgcctcca tcaactataa atctccatgg ttgtctattt
    50341 aatgtagatg gagctaatct tgcatagtga aatgcatcaa gaagtgctct ttcttctaag
    50401 atttctatac ttgcaacatt tccccattcg ttcatataaa caacatcttc tacacctagt
    50461 ctagtagacc ccttatctgt tacaacttgc atatcagatt ttgaataatt ttgcccagtt
    50521 tttgtagcat ttaatacttt agcattactt acattttctc catatccaat agctataatt
    50581 cctgttacct ctttatctga attaattcca agtttttctt ttaccttttt tccatcttca
    50641 aaagtaaccc aacaagaacc aattccaagt tctgttactt taaagattat actttctcct
    50701 atgtaccctg aattttcaat gtaattatct tttatgtcag ataatattat aatataactt
    50761 ggagaatcta tcatatttcc tttgtaccct gctactttat ctaaattatt aaaaacttca
    50821 cttctattca taattcttac atcaacatct atttctggaa ctagtttctt acaagattct
    50881 gagtatttct taatttcact aagatattct tctttaatat ctgtgttctt atattctcta
    50941 acagactttc tatttaatat gattgtttta taatccataa ttttatcctc cccaaactag
    51001 tattgtctta attatatacc cattaatata ttattttact catttattta ataaataaag
    51061 attacaattt tgtaattatt atttattaat aatattccac ttttacatta ataatgacca
    51121 gttgtgcaaa atccattgcc aaccaccaaa taaaaacata ttataaaggt aatataaaat
    51181 aacaaacaaa tcttaacaaa aaattaaact ttttttacac gaaagaaggc ttcccgttgc
    51241 cttctttatt tttataaaaa aataagctgt ttctaaaatg atttcacatt tttgaaacag
    51301 ccaagttatt ctataatgac aactataatt tgaggatgtg agggagagtt gtcattataa
    51361 atttagggta attatattat gttttaagct agttctttct atatttatat aatacatttt
    51421 atatatgaat tttatatgag attggtataa atgatatatg aaattacata tgtttatatt
    51481 atattaaatt ttattattac attttccaca acaatactca tatgtctcca cattatttgg
    51541 aatatttaca aatacaaatt ctttacagtt ctcacaatac tttaatatag atatagttcc
    51601 acaagtgtaa cattcaaata ttacacaatc ctcattttcc tctactattt caaacttttt
    51661 actatgttca ccacactctg ggcacttgtg attatttaca ttcataaata ctcctcctta
    51721 ttagtatagt tacatgtcaa aaacttaatt aatgtattct atattactta ttatatattc
    51781 tataataaat catattctaa tataataaaa caaattaaat aaaaaaaaac cataaatttt
    51841 aaatttatgg attaattctt gtaatgataa ctctatttga ggatgtgagg gagggttatc
    51901 attacaatag ggtattatat tatggttttt aagctagtct ttctacacct catatgatac
    51961 atatgctata tgaattttat atgattttta cataaatatt ttatgaaatt taaatttttt
    52021 agtcattttg aaatttgtaa aaagttctct aaaaatccac agcatcataa acagccaaaa
    52081 tttaagtaaa acatcataaa aaaatttgtc caataatttt aacaagtaat ctcacctcat
    52141 tataattatt gacacaaact taaataaaca atctataaat cttctataaa tcttaaactt
    52201 tccccctatt gatacacaat ttctagtttg tcaattttat tttgcatttc taagaaaatt
    52261 tcttcaacag aattgttaaa tatattgcct aaatagattc ttttatcttt ttgaaatgaa
    52321 taagatttta cactaccatc agaagaaata tataaatgac tccactctgc tccatatttt
    52381 gaaaacctct cctttgtatc tttaaacctc atatcttcta tttttattgc tttttctctg
    52441 tctcctctta ctacagtgtg accccttttt attaaactgg ttatttttat atcttctttt
    52501 aatttaatac gtgtatcatc attttttgaa tatactttcc atatcacttt atgacgataa
    52561 ttatctaatt cctttattaa gcttctatca atagtaaaac tatctttagt taccacaatt
    52621 aaatcaaaat ggtctaacat atattgaaat atttctctca tacttttatt ttttaaaata
    52681 tcctcaccaa taacctctat aaatctacag cctttctcat acatgcagtt caataaactt
    52741 gtgatttcag aaaaataatc atttgtatta ttatctccat ctatttctat agtaaagtac
    52801 aaaggagtaa tgtatgattt atttcctgtt atctcaaata cacttgatag tgtctgtata
    52861 tcatcttcaa acgttaagta tacattctca taaaacataa aaaattccat aactttttct
    52921 ttcatattat ggatatttct atatctattg gataatatat ttattatatc gtcagtagta
    52981 tttttcccat cacattcagc cagtataaca atttgcttcc aacttaagct atccacattt
    53041 ccgatacttt ttttatatcc atcttcttca tcataaatag ggccaattat aatgttttct
    53101 tttggccaca gatgaaccct agttccatct tttaatttcg gatatttatt ttttacagac
    53161 tcataaaatc tacttgtatc acccatgatt ctttactacc ccccatagtt taaatattct
    53221 atgctaaaaa tagcacttta tttttattaa ttcaacaatt attcaaaatt ggtcattata
    53281 tatgtttaaa tggatttaac atcaacctta tttatatgtt attgatgttt atatatgtta
    53341 tataaaatct tatttctcat acttcaatgt aatcttaact atctctggtt tacaattaag
    53401 cctaattaaa acttttgagc ctcctaagcc tttatttaaa atcatagtgc tattatcttt
    53461 ttcatatttt ccccagtcat acttaggaaa gaactctcta tttggagata atacacctcc
    53521 aacaaaaggt attcttatta tacctccatg aacatgtcct gctaaaacca aatctgctcc
    53581 ccattttgca tatttttcaa agaaaaatgg tgtatgtgct aaaagaatgt tatattcatt
    53641 ttcattaact ttacctagat tgtcttctac aaaattgtca cttagttcta attttttgtt
    53701 attagcaaat aaatatggat agcattccaa tggtataatt aaaccatata aattaagatg
    53761 gctattacct ctatatattc ttacagattc attttccata tttattattt tctttgaata
    53821 tagttcctta aaataatcct tatatagatg tttatacttt tttattaaag atttttgttc
    53881 atgatttcca attatatgat atacttcata tttttcaacc aaattatcta ttaaatctaa
    53941 tgcaacttga aaatttttat tttctccatc tactaaatct cctgttataa atataacatc
    54001 tgggtttaat gattcaattt tatctatcaa taccttatta tttttatcaa acaccttatt
    54061 atgtaaatca ctcacttgaa ctattttaaa gttatcaaat tcctttggaa tttttttgtt
    54121 gaaaatagta tattctgtcg tttctatatg ctgagtttca tacttataca gaatatacaa
    54181 taatattaat actaatactg tcattgaaac ctttataatc atattctctt cctctttatt
    54241 ctattttgtt aatattatta taatgctttt atgttttttt taaaacaata acatcatcac
    54301 atacatataa atcttttcga cattataaaa ataagttatc cttttctaaa attttcattt
    54361 attttagaaa aggataacta taaaattatc tataaacctc tatattgtga aatatagttt
    54421 ttcctttatt taaattttta tatatatgct ctaaagttcc atcaaaccta atagaatgtc
    54481 cagactctaa aatataagtt ttcccatcca cattaaggtc aagtttacct tctattacga
    54541 gtacatactc ttctaaaaca tgactatgtg tagatgaaac atgagtacag ttttcctcaa
    54601 gctcaattat aaaaagttca aaccttcttt gagggctaaa agggtatatt ggatataact
    54661 tcatgttccc tttttgctca acaataggct ctacttcttc tttctttata acctcatagg
    54721 tatttgtatt ttcatttaat agtgtagtaa aatttatttt aaatccagat gaaattttcc
    54781 ataaagtaga tactgtcgga cttgattcac ctctctcaat ctgtccaagc attgctttac
    54841 tgacacctgt catctttgaa gctttgtcta aacttatgcc catttcttgt ctcaataacc
    54901 ttaaattttc tcccacatta ggaaatttat tatccatgtt aaaatcctcc tgatagctat
    54961 ttgtattcta tgatttttac tcctgtaagt tctactatct cttttaattt taacatatga
    55021 ttgttacaaa tttcatcaaa ttcatatata taatcttcaa gccctaatgc cttatattta
    55081 tcgattccaa atttatgata tggaagtaac tccatcttgc ctcctggaac attttgttta
    55141 acaaataatg cagtatttct tatattttct tcactatcat ttactccata aataattggc
    55201 actcttataa ccatagattt attcaacttt gaaagcctac atatattatc taatataatt
    55261 ttattactta ctcctgtata ttctttatga atattatcat ccatagattt tatatctaca
    55321 aatatgtggt ctattttctc aaatacatca tttaccttat tccaatcaaa atatccacaa
    55381 gtttcaattg caatatttat gcctttatca taaaaaatat caactaattc tcttaaaaaa
    55441 tcaatctgaa gtgtaggttc acctccagaa aaagttatcc ctccattaga ttcaaagaaa
    55501 aatataaaat ctttttcaac ttcctctact atttcttcaa cactcatttc ttcggtcatt
    55561 atacaaatgg catctttaag acataccttg atacactctc cacataaatc acatttatta
    55621 tttatttgcg ttctatcaaa tagtgaactt atattttgag gacaaacatc tatacatcta
    55681 ttacaggata cacatttatc tttcataaca cctaatttta ctatgttact ccaggaatct
    55741 ggattagaac accacttaca ttttaattta catccttcta aaaatatagt agtccttatt
    55801 ccatctccat catttactga aaaatgttgt acttttacaa ctctaccttt tttactcata
    55861 atctacctca taattaaaaa ttgctatgtg aatttctagc tattatagca tcttgcattt
    55921 ctcttgataa attaacaaat tgagtactat atccagcaac cctcactaat aaatctttat
    55981 attcttctgg attttcttgc gcttttaata gagtatcatt tgatatcgta ttaaattgta
    56041 catggaatcc tcctaaagca aaatatgatt taatcataga tgttagattt ctaagtcctc
    56101 tttcagtttc caccaaatct tgattcagtc ttaaatttag aagtgttcca ccagtatgaa
    56161 catcatgatt tatttttgat gcagatttca ttgctgctag tggacttgtt gtatcagtac
    56221 caacaaatgg agaaactccc tctgtcaaag gttttgtcgc ttttcttcca caaggagttg
    56281 cacctactat ttttccagtt ggtacatagt ttgatatacc cataaatgca ctattaaatt
    56341 tagagccaaa aatatccttg tattttctag tttcagtata ataaaaatca gaaacttcaa
    56401 ttgctaatga atctacataa tcattatcat ttccatactt aggaacatcc aacgcaagtt
    56461 ttcttaattc ttcataacct tcccaatcat tatttagtgc ttttgttaat tcttctaacg
    56521 tagtcacctt atcctcaaat actaattttt ttatagctgc caatgaattt gaaactacac
    56581 ctaaccctat accagttaat acaggaccta tattatattt tgctcctcct ttacttaaat
    56641 caactccctt atccaaacat ccatctacac aagtagataa aaatggtctt ggtaccattt
    56701 ctttatgaat ttgttgagca acagtagttc ctataacaga actttttaca agatatgcta
    56761 attgctttaa aaactcatcc ttaagttctt caaaagaagt aaattctgtg atattttttg
    56821 tatctaaccc cattttttct ccagttaatc tactcttacc ttcattcata gcatattcta
    56881 aagctgctgc aaaattgata tttacggctg aagtccactg tcctgttttt ctaaaatgag
    56941 gaactacaca accacagtta ctccaatctc tagcatcttc tgcatcatat ccatcttgta
    57001 ataacatttg tgcccctgca ctatcgctgt gtatagcagg gaaaccagtt ccttgtttta
    57061 ccaatttagc aactgccatt acgaaattat ctggtgctcc ttgactcact ctaacactta
    57121 atcctggttg gtgagttttt acactttctg tagcctttaa acacatatat gagatatcat
    57181 tcgttccatc agtaccattt ctctttttac caccaacagt aagattttgg aattgattat
    57241 atcctgcaaa gtaatttgct gtatttgctg atatagtcca tacccattct gataacttaa
    57301 tccaaagtgc ttctatcaat tcttgagctt ctgattcagt tattttacct tctctagcat
    57361 cattttcata atatggatac atatattggt caaatctacc taaatttaat gccaatggat
    57421 tttctgatag aataccacct aattgaacaa accatacaaa ttgtattgct tcataaaaat
    57481 tagttggagg gtttgctggt acattcatac atatctctga aatttttata agttctaact
    57541 ttctcttttc atctgtttct tgcttactca tctcttttgc aagatttgaa tatctttgtg
    57601 ccaatgtcat aataccctgt gcaactatag aaacagattt gtaaaaatct atcttttcaa
    57661 tattttctga aactgatata tctaattctt taattttttt atctgcatct tccttaatcc
    57721 ctttatatcc ttttacaaac aatatatctt gataatctgg tgttacttca ccaactgcct
    57781 gtctccactt agaatcatta tctattattc ctgtatctac taatatctta gctgtatctt
    57841 ctgggattct tgctaagaaa acttcttcca aagattttcc cttccaatat ggaaatattt
    57901 cttttcttat aaattctatt tgttcttttg atattacata tgggtcttga gttcttttat
    57961 caaaagtatc catttctttg tctacccatt gccaagaaaa ctctggtgtc aatatccctg
    58021 ttcttctaaa ttttcctgct gtacctacta ttaattcatt ttcaaagatt tttataggaa
    58081 gttctttaca tgtctccaaa aaagctttag ctcttcttat acagatagct tctccctcag
    58141 tttttttatg tgattctgta aaaattctag ccctttcaca acatatcata ggtttagaat
    58201 taatatattc ttgtctaaat gcttctattc tattagtttg actcatttaa aatccccctt
    58261 tggataatat atactacatt tttgtatgtt ataacatact ttaattatat tatactgtcc
    58321 tttagcataa aatggaagca aaataactta ttttttttca tctaccttga acacctatat
    58381 attaatactt tttttgttaa atttataaaa tctaaaaaaa ttttctatga tatattttct
    58441 atattgttat agttatgtct aatatactaa tgatttgaaa tatcaaattt gtatactaga
    58501 cttagtttta aaaccttagt tgattgttta actttgttaa cttcaacatg tatatccttc
    58561 atataaggaa gctctacaac acctactccc ttattaaagt cttcttcaac catagaaaaa
    58621 atttctttct cagttaagtt cgtattagtc aatgatttaa ataaattgta tataaattta
    58681 atatatttat cactctcaga taacttatca tcttctggat actctttagc acagagaata
    58741 tctattgtta cttttccttc tttatcgtct tcagacatag aatagaataa acttcgaata
    58801 tttttttcag gtggtttttc agcaccattt atagatacta caaagctacc atctgatttt
    58861 gagttagtaa tactataacc actgtctatt atagctttcg aaaatctttg agataaatct
    58921 ttttttactt cttctctacc tttcgcatca ttaatctttt gtgagtaatt attaaatagc
    58981 tcgatagatt catctttttt atcttcaact tgttctttca atgaatcttt actaatttgt
    59041 tctgagctac ttaagttctt atcagataca ggagacatac accctaccat caatgctaag
    59101 ctaagattta aagccacaat tattgccact ctatttatat tcctttttac tttcatacac
    59161 aatcctccca tcacactaac cgctctaaag tattattcat tgcactagaa tatatttata
    59221 ttttctttat attaaagatt tattattcaa tacatatcac cttcctatcc aattcttata
    59281 acttactatt agtaaaatat tataagctcc ttaatacaga aataaggatg ttatcttttg
    59341 ttattaaaag ataacatcct tatttttttg tatcaataca tatgtcccaa ctggtaactt
    59401 aatcgcccca actgtcagta tcttggtcca atggtatata tatatttagt ataaatttat
    59461 cgatactatt ttcaaataat aattctccat tatatttttg taaagaagat ttaatactct
    59521 gaatacctat tccatgtacg aacttatcca ttttgtttgt taacaatata tttttattaa
    59581 aagtaagctg atttagttta ctattttcac atttaagtac aaaaaatgac cttgttatag
    59641 ttcctttaat tctaatatat ttattaacat tttcatccac tattttatca catgcttcta
    59701 ttgcattatc caaaatatta gaaaatatgc ttgacacatc tataggtttt acaaaattta
    59761 cttttgaaaa atttatagag caagtaaatt taattccttt ttttaaacat atttcactct
    59821 tttcgttgat tataatgtct aatatcatat ttcctgtatt atagatatat ttaaatgttt
    59881 ttatttcatc ttttaaattg ttaacatatt cattaatttc tttgctattg tttctaaggt
    59941 tgtctataca ataaatgtga ttatttatat cgtgatatag tttcttaact cgcatatgag
    60001 attcttgaat acttaaataa tgcgcatatt gcatatctaa cttatttttt attaattcag
    60061 cttgagattt taatctattc tcttttatta tttctttaaa caatagtata agaaatatac
    60121 tactagctcc taccaatttt ggattaacaa aattatcaaa atagtatcct tctgaatgta
    60181 atgacccaaa ccgttctaat ttttttaata cataatttac aagcatattc attgtattaa
    60241 ctaataaggc aaataataaa tatacataat ttctcttatc ttggctaatt aattttatag
    60301 actttctaaa aaagctaaat ataagatata taagaataat tattaaatta ctatatatct
    60361 gaatttttat agattctaag tgaggtacta ataaagattc tttagatgaa ataacattac
    60421 ctgtaattgc aaaaaatagt attctatata taacagcatc caaacattta taatatacac
    60481 taaatagata aaagaaaatg gaatacttaa tataacccat cttataaaaa taattatagt
    60541 atcctcccca agcaataaat gctaatatat aaaataaata gtttatatta ctaaagtaat
    60601 ttcctccatt aaataatcta cttatctgaa ttataatata aataagaaac aagacaatat
    60661 agaatactat tttttcattt tttttactat cctttttata aattaaaact ccgttcatta
    60721 tagaaaactg tataaatata gataaaacta ctaatagctc agtcataaag tttagcatat
    60781 tgtatcacca agaaatttta aaaatttctc cttaacttct ttatatctat atctactaat
    60841 aggtacctct tctccacttt ccagtattgc agtattaggc tttatatttt caacatatct
    60901 taaatttact ataaaacttt tatggcatct tataaattta tatggattta attctttttc
    60961 tattttgcct aaactatatt ttatatcaaa attcttgttt attgtgtgta ttagcatatc
    61021 ttttttttga acttctatat attttatttc atttaaataa atcttatatg tattagactt
    61081 attttttatt gtaatatgac tttccttatt tatttcaata tctttgatac aagttagcac
    61141 atgttttttt agttcttcca actctattgg ctttagtaaa tacctataag ctcttacctc
    61201 ataaccttct tgcacataat ctattaatga agttacaaat attatttcca tttcattgtc
    61261 tacttctcta atctttcttg cagtatccat tccatttagt ttttccattt ttatatcaag
    61321 aagtaatata tctatatctt ttaaattact ttccagtaac tcttctccag atatatactt
    61381 ttgtatctca tattctatac ttatatcttt taatatattc tcaaggtaat cttctattaa
    61441 aagttgtgtt tctttttcat cttcacaaac tgctatctta atcataaaat gcctccttac
    61501 ataatttcta gttaatacaa ttaaaatatt tataatatat ttaaagataa ttttgtatat
    61561 ctgatacttt aggataacat ttttaaatta tttttatcaa tactcaatcc cacacaacta
    61621 ttatttgata tttcaattta aagacagaaa ttactataat taaaaacagt acttactgac
    61681 aaaagaagat gtcttaaaat attaaaaaaa taattttagg acaccttctt ttatttattt
    61741 aaacttttta agccttaaat aatacattaa tctcctatat aattgtactg catataaaat
    61801 caacaatata atctgtagta caatagcagt tacagatgct ccataaccac tatataaatt
    61861 tcttatttca atattcaata aatatataaa tattactact aacataaaga atataaacat
    61921 attcataaat aaaattgact ttactttatt tgttttatca gaatcactat ataatttagg
    61981 aggtatgtct ttgtattctt tcgaccatat ataccatgca gatgtaccca taaaactacc
    62041 aatactccta aatacaagat tccagccatt tgatttatgt tcatcaaaat aattattctc
    62101 tacatcatag tagtaatcaa cagtgtattt tatttttctt ggacttccct tatgaaaata
    62161 aaatattcct ccaaatttat ttatcttata taaattatat cctttagctt caatatcttc
    62221 taaccatttc tctatcttat caggtgaact ataccagtca aatttgaatt ttattttctt
    62281 ttccatagca ctcattctcc aaaatgatat ttttaaatag cttaaaaatc tatttaaata
    62341 attatatcat tttgatacta attttaggtt acaatcatat atttaaaaag ctatttaaat
    62401 agtaataaac taatagccat aacacccatt cctgcaatca atccataaat agataaatga
    62461 tgttccccgt actctctagc tgatggcaat aattcatcta gtgatatgaa taccataatt
    62521 cctcctacaa ttgcaaatac aattccaaga gttatatcat ttaaaaaatt tctaagaagt
    62581 acatatccaa taatcgctcc taaaggctca gacataccag ataaaaagga ataataaaaa
    62641 gctttctttt tatctcctgt ggcataataa actggtacag atacagatat accttctggt
    62701 atattgtgta ttgcaattgc aattgctatc ggaatagcta ttgtaacatc atcaagagct
    62761 gatataaatg tagctaatcc ttcaggaaaa ttgtgaattg ctatagccat tgctgtaaat
    62821 atacctgttc tcaaaagaga cttatttttt ttgatattct tttcttctat attctccatt
    62881 ttctttattt catgtggatt ttcttcttgt ggaattagct tatcaataac agcaatgata
    62941 gccataccta taaaaaaagc tattacagtt gaccaacttc ctaatttctc tcccatagat
    63001 tttgtcaaag catcttgtgc tttaggaaaa atttctatca tagaaacata aatcataaca
    63061 ccagcagaaa atcctaaact tatagaaaga aacttagtat ttgttttttt agcaaaaaat
    63121 gctatacaac ttcctatacc agtagataaa ccagccaata atgttatcaa aaatgcaaat
    63181 attacattat tcaaataaat caccttcttt ttaattgata ttgattatca ttttctttat
    63241 gctatcatat atattttata tagtcaatat ttataaaaaa tatacacaat aaaaaagcag
    63301 agatataaac ttagtctctg ctttttcttt atagtatatt aaaattattt atttaagaaa
    63361 tccactgcat attgcacgta taaagcagtt ccaatttcta gaacatcttc atctatatta
    63421 aagcatccat gatgatgagg ataacaagca ccttttgact catttctagc tcctacaaat
    63481 gctagtgcac caggtgctat attcataaac tcagctaaat cttctgctcc tgttactttt
    63541 tcaaatagtg ttatacagtc ttctccaaat agcttaattg ctgcatctgt agctatcttt
    63601 gaacattctt tgtcatttat aactgctggt gttaagtacc catactctaa ttcagcatct
    63661 gctctatatg cttctgctgt agattttgct atacgttcta aaattccagg aatttgcttt
    63721 ctaagctctg gattaaatag ccttattgta ccttctaaga tagcttcact cgcaattaca
    63781 ttaaatctag ttccagaatt taaaactcca acactcacaa ctaatggttc cagaggactt
    63841 acttctctac taaccataga ttgtagattc ataactattg ctgaacttgc aagcactgca
    63901 tcaacacctt gatgaggaag tgaaccatga ccacctctac cttttacagt aattttaaag
    63961 aaatcagcag aagccattct tggtccttct tctaccgata tggtcccaga ttctacatca
    64021 gtccaaagat gtattccaaa cacactatct acaccttcca tagcaccatc ttgaatcata
    64081 gctcttgcac ctttaccaac ttcttctcct ggctggaaaa ataattttac agttccattg
    64141 atactatcct taatatcatt taacactttt gctgccccta gaagcattga tgtgtgacca
    64201 tcatgaccac aagcatgcat aagtccttca tttttagatt tgtattctac atcagtgcat
    64261 tcaacaactt gtagagcatc catatcaccc ctaagtgcta cagtctttcc tggattagct
    64321 ccttttatag ttgcaattac acctgtacct ccagctgata catatggtat ccctatttta
    64381 tcaagttctt ctttaactct ctttgatgtt ctaacttctt ccatactttt ctcaggattt
    64441 tcatgaaatt cccttctaag cttaattaca tagtctttat aactcttcgt tatttcttta
    64501 atatccattc catacctcca agtagtacac attcttctta tttaaaatac tttttatcac
    64561 tcaaatacta tattagattt acaaagatac ctgctattac tacagaagct attgtaactg
    64621 tagtaaatcc tccaacaagc atctttggaa gcatcttatc cattaaaaat tctttttctt
    64681 ctggtgtttc agccaaagcc tttactgcct cttcagttaa tatatagttt ggtggaaaac
    64741 cataaagtga tgtaagcgaa actgaaaaag ccatttcttt actttcacct aaaagcttac
    64801 ctactataat agagaatatt cccataccta ttacaccaaa tattatgatt cctacaagag
    64861 gaactgccat ttcaacaagc attgctggtg tagcttttgc taaccctgca aatataaaag
    64921 ccatcaatga tgtcattaac catccaaatg aaccagattt attaagtggt tttctatcaa
    64981 ctattccaag ttctgatgct attacaccaa atattaaaca tataacatat cttgatacaa
    65041 cttcatttgt aagatttgta aattgtactg ctaaccatgc tacaaatcct aatctaagta
    65101 ttatcatata tgtcgtatca tatttttctg gtaagtctgg tattatctta aatctgcttt
    65161 tttgttcagg taaatcctta actttttctt catctgtatt tacagttact tttccacttc
    65221 taaagtctga taaaagtctt tttccttctt ttttaagcat taatgctgta ataggataac
    65281 ccgcaaatcc ttgtgcaaca tacatcaaaa ttgcaagtac tgataaactt gcaagacctt
    65341 ttgctgtagc agcatctgcc atcattatag atgcaactag ccctccagta agaggaggtg
    65401 tagctattac tgctgtatcc catccaaata ctactgtccc taatgccaaa gcacctacac
    65461 atattcctac tattcctgcc aaggctatta ctattgtttt ccattgacct gctaattcct
    65521 taatactcat catagttccc atatgagtta ttaacaaaag catacctaat tgagctaatg
    65581 gtgttcctaa agcggctaag tccacaatat tttctgggaa aaaagtccaa aatcctacta
    65641 taaatataat tgctgataca aaaaccgacg gaacaaaagc tttagttttt gctgaaacta
    65701 tatctcctat cgtcagtgat actaaaacta gacaaaaagc tgttattgcc tccatacaaa
    65761 atcccccctc ataataaata tatttttata aaatgtatgt atagttatcc attattttac
    65821 tacttttgaa aaacatttca agtcaaaatt cgattttttt cataaaattc gataaattcc
    65881 ataaattaaa gttagttttc taaattattc tttttgtaaa aacgttatcc cgaccattgg
    65941 ctatttaact ctattcttac aaagagaatt aaatgtaatt tgcaaaaaat aaaacatagg
    66001 atacatttta ttcataaaac atcttataaa tataaaatga attgtcttta tgaatcttaa
    66061 tatatcctat gtttgtaagt ttaatgtgta tgttagctat ggtgtaaaat ttgtatacta
    66121 gttattgtgt aacctactat atactccatt tttgtttact agctcttcat gagtacctct
    66181 ttcttcaatt cctttatccg tcaatactat gatttcatca gcatttttta tagtagtcaa
    66241 tctatgtgca acaactaaat ttgttctatc tttacttaat tcctctaaag actcttgaat
    66301 ttctctttct gttacattgt ctaaagcaga tgtagcctca tccaatatta ttattggagg
    66361 attctttaaa aagattcttg aaattgaaat tctttgtttt tgcccacctg ataattttac
    66421 gcctctttct cctatataag tatcatatcc atctggcaaa gtctctacaa agtcatgtat
    66481 tctagctttt ttagcagcag ctatcatttc ttcatctgta gcattagggt tcccacaaag
    66541 aatattatct cttatagttc ctgtaaataa aaatacatct tgttgaacta tacctatatt
    66601 ttttctcaat gattttaaac taacatcttt tatactcttt ccatcaattt ttatatcacc
    66661 cttatcaaat tcataaaatc ttggcaatag attacataat gtagtctttc ctcctccaga
    66721 aggtccaact aatgctatag tcttaccagc ttttatagat aaacttaaat tatccaaaac
    66781 ttgagtctta tcttcatatg tgaaagatat attttctatc tcaatgtcac cttttacatt
    66841 ttcaagttca ataggatttt tagcttcttt ttgatggtct tgttccatta tctctatgaa
    66901 tcttttaaaa cctgtcatac cattttgata ttgctctgta aagtttatta attttttcat
    66961 aggttgtata aacattttta catatagtat ataagcagca aaatcaccca aagtaatctt
    67021 tcctatataa gtaaaataac caccagctat tacaactacc cactctaaga tatccatgta
    67081 taaattcata ccagagtaat attctgccat taccttataa gaatcttgtc ttgctcttct
    67141 aaataattta ttgcttctta caaacttatt taactcttct ttctcagtac aaaaagactt
    67201 agttaccttc atacctgcta tactattttc taaagtagca tttacatcac ctatagtaac
    67261 tctactcttc ataaaagcaa tattcatctt atctttttta gctattgcaa accaaattat
    67321 aaacggtaat atagcaaata ttataagcgt aagaggaata tttatatcta taagtataaa
    67381 gaatgaacca accaacatta ctatagaaat gaataaatct tcaggcccat gatgtgcaag
    67441 ttctgttata tccattaaat catttactat tctagacata gttactccag atttgttatt
    67501 atcaaaatac gtatttggaa gtctttgtaa gtgtgtaaat acctcatttc tcatatcagc
    67561 ttgcatatct acaccaataa catgtcccca atactgcata aaatagttaa gccctgcttt
    67621 tgctataaat ataagtataa gtgctactgc aaaaactact aacattctta agtttttatt
    67681 tggaacaacg tcatccatta tatttctagt tatcatagga taaactaaat cacataagga
    67741 aaatagaaaa gctgctataa ggtctagtgt aaaaattttc ttatatggct tataatattt
    67801 gacaaattgt tttatcataa gtattaaatc cctcctttat tagtacttct aaaaaatacc
    67861 cataaattag tataacataa caataacttt aaatctttta taaacttaca aagtaataac
    67921 aatctttttc ataaaattga agatttatat catatagttg tatacttgaa acaacataaa
    67981 aagagctata tctctatatt taaaatttta taaagataca actctatatt taatactaaa
    68041 ttttttttat aaatacaaaa ctacttcaat gcatttaata tctttttatc taatgctgtt
    68101 gtatttatac ctgttatata tcctgttgcc tttattgtag gtatatcata agttgttggt
    68161 agtatagtag tagatacgat taaatcagca ccttcttgtt ttgttgaaca ttcagcaatt
    68221 ttacattgct caacttctgc ttgtatatta ttttctttaa ccaatctttc tactctgtca
    68281 caaactattg ttgatgttgc gattcctgct ccacaggcta ctaatatttt tttcatatat
    68341 tgtcctccta caatttcttt aatattttat aactcaaaat aaaattgata aatttcttat
    68401 atctttattt atataaataa ttatatcatt ttatataaga agaacatctt aaaattattc
    68461 ttttaatatg ttttttattt caacattgct tatacttaaa atttcatttt ttatacaaga
    68521 ctctatgtac tttgatatat ttttataatc atttaaatta aactgttcaa tattcaattt
    68581 atattctata tcactgacaa tacctatcaa atcagactta ttagataaaa tatcctcata
    68641 cttacctttt ctagttactt ccaatctttt aaatctataa tttttatatc cttctatgat
    68701 aatcaagtcc atatcttcat ataattgaat cattttatat aatggattct tctcttttag
    68761 ttcttcaata tatgctactc gtttatctga tattatacag acttttctcg ccccagattt
    68821 tctatgttta taagtatctt ttccttcctc atccatatca aaatcatgac aggtatgttt
    68881 aataactcca acacgatacc cttttttatt taattctttt attatgcctt caatcaacgt
    68941 agttttacct actcctgaat atgagacaac tgacaatata ttatacataa aattgtgtcc
    69001 tttcataaaa ctatctaata acaacatcca ctaattgatt ttcttttatt gtctcattct
    69061 ttttaatctt aatcatacaa ttacttctta gagttgcaga taatctagct tttgcatctt
    69121 tcttatcatt tagctctaca tacaatttac cttcacttgt atatagtttt ccacttacaa
    69181 atctatcttt atttgaaagt ttattaaatt ctcctttaaa tatagctttt atatgatgtg
    69241 ttcccttctt atatgttaaa tgctcaataa caggaactat cacattatca aataccacta
    69301 ttgctgcatg tggattacca gaaagaccaa ataatagctt ttctcccaat gtacctacat
    69361 aacaagctcc accaggttta atgtttatct tccaaaataa ttctgttgcc cctatttttt
    69421 tgaatacatc tggaattaaa tctttatctc caacagaaac accacctgtg gtaattaaaa
    69481 aatctacact ctgtaacata ttctttacct ttttttctaa ctccaatata tcatcagaac
    69541 aattgcatat tgtatctgct tgtattccaa gttttaataa tcttgaatat aaggtatatc
    69601 tattactatc gtatatttta ccattctcta aagtctcatt tatatcttgt agttctgtac
    69661 ctgtattcaa aattccaact tttaaatcat cataaacagt tactttggat attccaatac
    69721 ttgctaatac tccaatacca tcatatccta tattctgatt tttattaata atcaattgcc
    69781 ccttttttat atcctcaccc ttaaatatgt aattatcgta ttcctttaat tttatattta
    69841 aagttatcat atcacctata actgttacat cttctttttt tattacacaa tttgcaccct
    69901 gtggtatctt tccaccagtc attatcttca ctgcttcatt tttatttaat accctattaa
    69961 atacatctcc tgcatacaaa gtccctataa cctttaaatt tctattttca gaatttgcat
    70021 tatatgcata accatcatag ggtgacctat caaatggagg actatcaatt gttgaatata
    70081 tatcttctgc aactacctta tttactgcat ctataagatt tactatcttg accctgttta
    70141 ttggtaaaac atttttttca ataattttta tggcatcttc taattctatc attttaaata
    70201 ctccccaata tattttttat ttaagatatt tctatgtaat atattataga ttataaaagt
    70261 tggaaatact tttatcttat atttaattat aactaatagt tatctataag tgcagttcaa
    70321 attttataaa tctaataaaa aaactgttcc cagctagaaa tttccttcta tcttgaaaca
    70381 gcatcatatg ctttagaata ttttattcta ataaagttcc ttttattatt tttacaattt
    70441 tatcactttc aatagttttt atagatttta ttttgttatc cacaatactt attgtaagta
    70501 cctctttttt taatattttg ttatcttctt tcaatctata actcttaact actttactgc
    70561 cttcatgatt atatgctgtt aaatcataat tcgcatctcc tacaatttca tttattctgg
    70621 aatcttcaac accaacatac tctcccaggt caatatgtct aaaattttct agtgatacag
    70681 ccgatttttc atggtcactt ttttcaatca ctatactaga ttcagcatca atgactgata
    70741 taccttgtga tgaaaaagaa ttggtttcaa cattgacaac tttattttcg ttaatatcaa
    70801 catataaagc acttccatct agttcatcat ttccagtata ttttggataa actaatgtca
    70861 tataacttga tgtatttata tcttgcattg tatttgattc ttttaaaact ttaggtttta
    70921 tataataaaa tgtattataa ggtataccca tattctttat aatgtactta taatctttat
    70981 tcataatttc attaacatca ttttgaactt ttgtcatagt tttttgctgt gttgctttac
    71041 ttgctacttg atttttctct ttagtatttt ctttatgaca tccaacaagt ataataccta
    71101 aaatagttac acaaactaat gaccttttta acttcataaa tcaatcctcc tttcttaaat
    71161 tttatagtat ttatctatat ctcaatttac agttatctct tttttcaata attatattta
    71221 ttatattata aaataattat ataatattta tttgaattta ataagattaa gaagctaatt
    71281 gtaatttttc tgtaataaaa aacactttaa agttgaattt tgaaaattca atttacgata
    71341 tttttattgt aagtacctta caacattata ccaaattatt cctaaacaat caaaaactcc
    71401 atgaatattt aaaggttttc tattttaaaa atcacctttg actattaatt tatcaaatat
    71461 gttataatag ttttagataa tttaaggagg attaaataat ggattttaaa caacttgaag
    71521 tatttgttgc tgttgcaaaa catcagagtt tttcaaaggc tgcaagagaa ctttttttaa
    71581 ctcaacctac tgtaagcgca cacatacaga atttagagag agagctagaa actgttctta
    71641 taaatagaag caacaaagtt attacactca caaaatctgg tgaaattctt tatgaacatg
    71701 ctatatatat attgaataat tgcaaacgtg caatttatga tataaaagaa tattcaggaa
    71761 aaatagaagg tatcatagat atagcatgta gttccatacc tgaaacttat attttacctg
    71821 attttatgaa gagtttttct atgagttatc cagatgtaaa attttccata agccattatg
    71881 attctcaata tgctatatca gaaattttaa atgaacgaat aagctttgga ttagttggtt
    71941 ctaaaatcaa taatcctcaa atagagtacc tagacttatt agatgatgaa cttgttctta
    72001 tcactccttc agattttaaa attgataata aaaataattg tatcgatata ggagaattgg
    72061 cttatctaaa ttttattatg agaaaagaag ggtcaggtac aagaaactta atactaaaca
    72121 cacttagtaa aaataacttt ccagtaagta aattaaatgt aatcgctcat gtagaatcaa
    72181 atgaggctat taaggaaatg gttagattag gtcttggagt atcctttata tcgtacattt
    72241 cagctattga ttatctcaat gcaggtaaaa taaaatgtta taaaataaag gatgttgatt
    72301 ttactagaaa gtttttcttc atttactcta aaaagaaaac tttttcccca ttagaagata
    72361 aatttctaaa cagattatgt gagtatttcg aaattataat ataataactt taataaagta
    72421 gtgcttaatt ttgagtttat aactaattaa taagctaatt ataactatca cataaatgct
    72481 tataaattat tatgaaccat ctttcttttt tatttaattt agtcaaaaaa tccctcgttc
    72541 aaatgaactt gggatttttt tatttatact actccaatag cagccaatac tatacaaata
    72601 atcataactg aaattaatat cgtagttgtc tttacctttt ttcctaataa ccaatacata
    72661 ataccgaata tcatagctgg aagcatacat ggcattattt ggtctaagta agtttgaata
    72721 ggctctgccc attctccact acctacatta acactaagtt ttaacattac attagatgca
    72781 gtcatacctc caattaccat aagccctaac attgaagctg cttccataac ttttgaaact
    72841 atacttgaac cactcacatc tttaaagaat tgagttccat acttaaatcc tttatctaga
    72901 catatatagc gtataataaa atgaggaaca tttattatta aaaggaataa aatcggtccc
    72961 attatgttac cctgagaagc taaagctata ccaaccccag ctgctataag ctttaatgtt
    73021 ccccagaaaa atgaatctcc tatcccagaa actggaccca ttaaacttga tttaacagca
    73081 tttatactat tagcatcaaa ttctttattc tttgcatttt cttcttccat agctccagat
    73141 atacctacca aaagagtact tatatgagga gtaactgaca taaattctaa atgtcttttt
    73201 aaagccttag atttcttttc tttatcatct ttatataatc tacggattat tggtgccatc
    73261 atgtatgcat atgctatatt ttgcatacgt tcgtagttcc aagatgaatc taatgtcaat
    73321 gaccttctaa aacatttcca aaagtctttc ctcgttattt tactatctgg tgaaattgtc
    73381 tctaacttct tagaactcgt tgtcatctac tattacctcc ttctctccta caaagttaac
    73441 atatattaaa gctattgcta atccaaacaa tgcaactcct gttactgtta tgtttaggta
    73501 agcaaccaat ataaatccta ataataaaaa tgctactgtt ttcttattaa gcatcattct
    73561 agctaacatg gcaaaaccta ttgctggaat cacgcctgct gcaacatcca ttccatgagt
    73621 tacatatgat ggtataaatg aaagtatttt ttctattact ggaacaccta atgaaaatcc
    73681 tatacctact attattgcta atattaattt atttcctata ccaaataata attgcacacg
    73741 ttctacgcct tcaatattcc cctcttctgc ataacggtca gcaatatgag ctccccatgt
    73801 aagtactact gtcattaaga agttatctat aagcaatact agagttgcta taggaactgc
    73861 aagtacaact gctgctgata catcttgacc cgttaatatt acaaacgctg tggcaataat
    73921 agaaccagac acaaaatcag gaggattact tgccccaaca ggaaatgcac ccataaatac
    73981 taattctaat gttgaaccta ttactatacc tgtatgaaga ttacctagtg ctaaaccaac
    74041 aagtggtgca acaactatag gtctattatg cattgtagaa cctacaaaac tatgcatata
    74101 tgcaaagaat gcaattagag ttatcaaaat aacttgtgta aattccattt tcatccccct
    74161 aaaattatat taatttcatt acatttgtag catcatcatc aggaactaat tgtacaaata
    74221 catttacgcc ttctgaatct aactctttaa tcatctttat atcatctttt gatacatgca
    74281 ctgctttaga tatattttca cgattatcat ctgattttgt tccaccaagg tttatagatt
    74341 taatagcttt tacctcttta gcaagtctgt aaacatcttc tacagattca caaagtatca
    74401 ataagttgta tttatcagta acacctgagt taagtgcttt tatagaatct gctatgcttt
    74461 tcattactaa cttaacatta gatggtttag ccattttaag tcctgccatt cttaattcat
    74521 cttttaataa gtcatcactt gctatcaata tacagtctgt acttaaaaac tttgtccatg
    74581 taaatgctac ttgtccatgt ataagtctgt ggtctactct tactaattta atcattataa
    74641 ttcctcccta atttttttga tttcatccat gaatgttttt acgtgttcta cactaacatc
    74701 cccaaaatct ttgtaattat ctttaaagta acttcctatt attgccatat ctcctaattt
    74761 aagctgtttt tttgcatttt ccaatgtaac tccagcagct ataaccaatg ggaagtctcc
    74821 taaattttta cgaaacagtt ctattttttc cattgatgtt tcttgacctg tagcattttc
    74881 tgtaactgct atagcatcac atcttgtcat tcctattttt aaatcttctt caacatcatt
    74941 ttctgataat actggctgat atttaaaacg tacgcctcca attaaatacg ctgggcattt
    75001 tgaacgttgt aatttaaaaa actcttctaa agtagcttca tctctaggtt taacatgacc
    75061 tactacagaa tcaacctgta tataactagc attatatttt gttgccagtt caaatcccat
    75121 agtatcaaca tttaaacagt ttactccata tggtattgat aaattagctt ttgatacata
    75181 ttcaagtatt ctttctaaat cataataatt accatagtaa ttttctaaca ttattccatc
    75241 tacaccattt tcttcaaaga ttgtaatctc ttttttagct ctttcaaaga tatcttctgg
    75301 agtatctcct tttaagtgta tcattgctat aattggtttt ttacttttaa atactgataa
    75361 tattcccttt tttttcataa actaaaatac ctcttcttct tctttaattt gtaatgtcac
    75421 gctttgtatc cctcttctag attcttccac taattggtct atatcttcaa ctgttaattc
    75481 atcagaaaac cttgtaagaa gttctaatac catattcaaa ttcattccag aaaataacct
    75541 aacattatgt agattagtta atcttaacat tgctgtacat acacttgctc catataagtc
    75601 agataaaatt atatattcac attctttatc ttctgatatt gttttttcta attctaaagc
    75661 aaaatctgaa gcactttgtc cagggtacaa accatacgaa ctgacacaat ctgctaaatc
    75721 tcctactatc atttttactg catttaaaag cccttttgaa aagtctccat gagatgctaa
    75781 tattatcttt ttcatactca tcctcctact aaattataga ttatatttct gctgatactg
    75841 catatttgta cttatcactt cttataaatt gctcattgta atataagaca tcattatttt
    75901 ctgtatacac cgattgtctt actttcaata gtggcatatt acttgcacat ttaagatggt
    75961 cagaatattc tttgtttgaa tgttttactt caaatatatt ttctactcgt ttaggtaatg
    76021 tgcttatatt attagatata acctccatta aagatttatc ttctaattct tcttttaata
    76081 aaaacatgta atctattcta aaatagtcaa cttcaaaaat aacaggtact tcatctatta
    76141 atctaagtct tttaatacat attaccttct cttctagttc aatacttaaa gcttcagcta
    76201 cttgcttatc tgcttttttt attaaaacag agattatttt ggtacttggt tttgcattaa
    76261 tacgatgaca agaattagta aaactatttc ctgcacatgt tgcttctatt ctctctggta
    76321 ttgttacata agtcccttta ccacgttttt tacataatat atcttctttt acaagttcat
    76381 taagtgcatt tctcacagtt atacgactta tattaaattc tttacataag tctccttcag
    76441 atggaagttt atctcctggt ttatatatgc cagatgctat ttgttttttt atgttgtcat
    76501 atagttgttg atataaagga acaaaggaat ttacttctaa atccatttct tttttttgtc
    76561 tcttttcatc cattttgctc acctccctat gtaacatttt tataacatta tataacaagt
    76621 tctttattac atattataac aagatgaaat cgttgtcaat ttttttttaa ataattttta
    76681 atttgacagt attttctttt attttctcta gtgtgacaaa ttgctatttt tacataaaaa
    76741 taagactgtt gtacaacaga ttaaattgtt tatacaacag cctttattca cttattacat
    76801 ttatattttt acttataaat ttatattaaa aaatgcctta tatcccttat acatttcata
    76861 tatgtctact ttagagacaa tctcatgtgg tgcatgcata tttaaaactc caacaccaca
    76921 gtctataacc tctgcacctt gatttgccaa tatatgggct atagttccgc ctcctccttg
    76981 gtctactttt ccaagttcag cagtttgcca tattacattt cctttattaa aaattccctt
    77041 tacttctgac ataaattcag cattagcatc attacatcca ctctttcctc ttgaacctgt
    77101 atacttagtt aaaactactc catttcccat atatgccgaa tttctctttt catatgcttc
    77161 tccaaaattt gggtcatatc cagcagaaac atcagctgat aataccttac tatttgctaa
    77221 agctcttctt actttaatat cacaataatc tccttctaaa gcaatcagtt cagccacagt
    77281 attttcaaaa aactttgagt gcatacctgt attcccttta gaaccaattt cttctttatc
    77341 tacacataat gcaactgaag taaattctgg ttgttcagtt tctagtatag cttttacagc
    77401 agcatatgaa cataccctat catcatgccc atatcccaac accatagacc tatcaagccc
    77461 taaatctcta gccttaccag ctggaactac ttcaatttca gcacttaata aatcttcttc
    77521 aactatattg tatttctcat ttaaaatctt taatatattt gctgttatag gttctttttc
    77581 ttcatcttct aaaggaatat tcccaattaa tatatttaaa gcttctccac taattccttc
    77641 tgatagtttc ttttgcattt ggtctccagc caaatgaatc aataaatcag ttacacaaaa
    77701 tactgggtca ctatcttctt ccccaataga tatgtccact tttgttccat catttaatat
    77761 aactatacca tgtaaagcaa gtggaatagc cgtccattgg tattttttta ttccaccata
    77821 ataatgagtc ttaaaaaaac ctagattact ctcttgatac agtggatttg gttttaaatc
    77881 taatcttggt gaatctatat ggcttcctat aatcttcata cctttttcta tataattttt
    77941 acctattaca aaaagtgcta ctgccttctc tttatttatg acataaatct tatcaccaca
    78001 acttatgctt cctttttcca tagcttcatc tattgaaata tagttatttt ctttagccaa
    78061 ttttataatt tcttttactg aaagtctttc agtctttgac ttacttaaaa actccatata
    78121 attgcgagaa tattgcataa tttgttcaat agtattttct tttctttcaa aatcccaagc
    78181 attcttaaat tcgtacttta agttcatatt ttcctcctac taagttctaa tttttattgt
    78241 ttttcatgta ttgctcatat tcttctggtg aaactacttt gacactatct agtcttgatc
    78301 taaagtgggc tctaaagttt tctaaatatt ctttccttaa aatttctctt tctttgattt
    78361 catcagcaga aaggattccc tctttatttt tctttgctaa ttcattaatc ctatctaatt
    78421 tcttcttgtc aaacattttt tcctcctaaa aaacctctat ttatttaata aaataattta
    78481 ttgcttttta tatctaactt gtttttatat tcacaaaaaa actcatctat attatcactt
    78541 attatagata ttcccttttc tagttcttcc atgcttggac gagctatatt tatcctaaag
    78601 aatctatcat ccactagatt gtcaaaaaaa taagtccctg gaagcattga cactcctttg
    78661 tttaacataa aatttgtaaa tgcttgagat gtatatcctc ttggtaattc taaaaaaaag
    78721 tttattcctc cacaagattt tctaactttt aatttaccac tcaatttgtc attaatcaag
    78781 ttttttgcca atttatactt atcagtatat atcttctcta tatgactcaa ataattcttc
    78841 caatcaaaat tattcatata gtaatacatt gatttttgaa ttaaacctgg tgttgatata
    78901 tctgatgaat atttagccca taaaactttt tttaacaact catttggcat ttctacaatt
    78961 cctatcctaa gacctggcat aagtattttt gaaaagcttt ttatatatac tactctattt
    79021 ttatcatcat aacttctaat tgttctattg tcctttgatt caaaaacaaa atcacttata
    79081 aaatcatctt ctattatata aaaatcatgt tcttctgcca attctatcaa tttctttttt
    79141 ttatatgttg agtaagatat tccagttgga ttttgaaaat taggcataat gtatataagt
    79201 cttggtttta ttttttccaa ctttaatttt aaaataccta tatcaattcc atcatctaac
    79261 ataggtatag atattatttt tgcacctcta cttttaaaca cttcaattgc tccattgtaa
    79321 gaaggttctt ccataaaaac aacatctgaa taacttataa gtcctttaca aactatatct
    79381 ataccttgtt gagcacctga tattatttga atattttcct tagtagtttt tatatttcca
    79441 tcacttagat actctaccat tttttctctt aattcttcag agccaagacc ttcatcatat
    79501 tcaaatattg aactaccatc tttagataat gccatattta cagcattttt aaatgaatcg
    79561 ataggaaaca tatcattaga tggattccca ttgtcaaaat gaattaaatc ttctctttgc
    79621 acaataatct tatttttcct gttatctata ccgcttttat aagaatttaa acttgataca
    79681 aaagtaccac tccctataat tttatataca tatccttcat tttctaaaag ctcgtatacc
    79741 ttaactatag tagtgttatt tacttgtaaa aaatttgata gttttcttat tggaggcaat
    79801 ttttcatgtt ctactaactc tttatttatt atcaattctt ttatatgatt aaatatctgt
    79861 atatatttag ttgatttttt ctcatttaaa tctattctgt atttttccaa atttatcacc
    79921 gctcattgta tttatatttt attgatgctt ttatgtatat ttgatattat ttagtatgta
    79981 tatataatac caaaattttt ataaaaaggg gaaatattta tgttttacga ctatcacatg
    80041 cactcaagtt tctctacaga cggaaaatct acaatggaag aaatggtaaa aaaatctatt
    80101 gaactcggtt tggaggaaat ttgtttcaca gaccatgttg actatgatgt atatgctgat
    80161 gattcttttt caattgtcta tgaagattat tttaagagtt tagagactct tcaaagcaaa
    80221 tataaagata aaatatcaat aaaaaaagga attgaatttg gagttcaaac tcaattaatg
    80281 gatacataca aaaaggaagc acatcaatat ccattggact ttataatatg ttctatccat
    80341 gctatagata caatggactt ataccttggt aattatttta aagataaaac tcaacatgaa
    80401 gtttatgaaa attactatct ttatttatat aatattgtta agaattataa agattactct
    80461 gtcttaggtc atttagattt gattaaaagg tatgcacctt atgacactat tttagatgat
    80521 agactatttt ctgatataat tgaagaaact cttaaacaag ctatttatga tggcaaaggt
    80581 atcgagataa atacctcttg ttatagatat aatcttccag acctaacccc atctaagtat
    80641 atacttcaaa tgtataaaga cttgggaggg gaaatcataa ccacaggttc agattcacat
    80701 catataagtc aagttgcatg tgagtttgac tacatatatt cattactaaa aaatatggga
    80761 tttaaatatg tatctaaatt taataaattg aaaccagaat ttataaaatt ataaattttt
    80821 acacctcctt gtgaatatat ttaaaagata aggaggtgat ttttttgaaa gtaccttatt
    80881 tagtactatc aacagttatt ttatttatat ccaattttat tgtaagaata tttggttttt
    80941 tatataaaat attcttatca agagcactag gtgaaacagg tttaggtatc tatcatatga
    81001 tttttaactt tttgatgatt tgcttagctg ttacaacaac aggtatacct actgcactta
    81061 gttgtctagt tgcaaagaga aaagctttaa acgatagaca caatactaat gctttattta
    81121 tatcaacttt atatatatca tttttcgtag cactaattat atctatagtt gcatctttca
    81181 atagttcttt tttatcactt aaatttttaa aagatgctaa attaaatcta tttatactag
    81241 ctgtttgtcc tgctatagtt ataataactc tttcaaacgt actaagagga tattactatg
    81301 gcataaagaa tgtaaaaatc cctgctattg gacaaatcat tgaacaaatt ggtaaaatat
    81361 tatttgtttt tttacttgtt atgtacataa ataataaatc tatgaattgt tatatagctc
    81421 tattaggtat atcaattggt gagttgagta atattatatt tatgcttatt tgcttatggc
    81481 gagattcatc atttgacaat aggtatatta taagcataaa agatttttat aattcttcta
    81541 tggaaacatt aaaaatgtct attcccataa cttgtaatag aatgtcaaac atacttttgc
    81601 aatctataag ttctatgatg ataccatcaa gattagcatt atcaggaatg acttatcaac
    81661 aatctttaag tatgtatggt attgtcagtg ggatggtaat gccttttata tttttacctt
    81721 ttactgttgg ttcagcgctt attgtaaatt taataccaac tatttcacag gaaattgctc
    81781 taagaaagcg taagagtgta attaaaaaaa tcaaatactc catacttctt actttatttg
    81841 taggcatact atcatcaata tttttttatt tctttggaaa agatttatgt atattagtat
    81901 ttaaaaatac acttgcagga gaatatctaa aagctatgtt tttagttcca ctatttatgt
    81961 ccctaaatca aactctatct ggcattttac attcaataag aaaagaatta gcttcaagta
    82021 taaatactat tactggcatg ttaattcaac taatagcttt atatgtattt cttccaattc
    82081 caggacttaa tatttatgca tacatataca caatgacgat agtatcaatc tttacttgtc
    82141 tattacatac tatagtgctt tttaaatcac taaaatctat acgctagtta taaaaacgtg
    82201 aaggctacca atgtaaatta tacactttgg tagccttcct tagatgattt ttatttataa
    82261 tttaaactgt ctatatatct acctatctat ctgtggcaac ttggctttcc acttccatga
    82321 ttaggtccac attgcgaaaa atcacatact ttagagaaag tatcaacaag tcttggttgg
    82381 attggatttg gtgatgctaa aactactatt tgttcactta ttaatgtgct aactgtttct
    82441 tgtaagcaaa gtactaaatc tatatcattt ggtataatta attcatagaa aggttcacaa
    82501 cattcgttgc attctaattt taatatagat tttcctatac aatctacagt taagttagtt
    82561 tgatattctt gtcttaaagt aacagctctt ccgtcagctg gcaagcatat tggtgctgaa
    82621 agtgtgttaa aagtaaattc tacataatca actcttctct tacatccacc tcctgctcta
    82681 actgctggga aagctaatgc aacgaactct gtacatccac atctacctct tagctctagt
    82741 actaaattac gaactgctac agttaatcct ctttgtttat aagctactga tttgcctttt
    82801 ccttgtctac agcactcaga gtttctttct ccacaaactg caaattcaaa agttgtttca
    82861 cagtttcttc ctactatatc tcctaatggg tctaaatcga aatcttctaa agttgtcatt
    82921 cctgtgtcta taacgattcc atcattactt aagcatattt tttctatagt tacacttgct
    82981 tgacctgcac ttggaactga accaaatact tctactactt ctgtttcaaa agttaatggc
    83041 tctccatttg gtcctgttgc atctgtaaat gtttggaatt gcatagtatc aaatattcta
    83101 ttagcctcta ttgcaaatgg cactgcattt gatacagaga agtttcttgg agatatagga
    83161 ttacagcatt ctggtccaca tttgttttca aaacattcat ctgaatccat ttcacatggt
    83221 tcacaatcac atttacaatt gtcatggcat ccacaattgt catcacatgg attaggtttg
    83281 catggattgc atgggttagg tttacatgga ttacatgggt tgcatggatt gcaatcatca
    83341 tggcactcac acttattatc agtattacat ccattatgat ggtgtgattt tttaaaacct
    83401 ctcatgtctt ctgaatttat ttcatctgta tacacttctt cttcattcat tgtagacatt
    83461 ggctgattca tcattcttct tttatttttt ttataatctt gcatttttca ttgccctccc
    83521 tgtaagcgat tcttattaag tctttggctt tttgaagcct aattaatact atgcttttat
    83581 aatcttaatt gttacttgct ttttgaattt atcaataatt aggcgtattt agtagaaaaa
    83641 tgcatattaa taaaaaaagt actactattt gaaatagtag cacttttttt gtcccgaaac
    83701 accggtggct aagtaaattc acaccctagg cactcccagg tgggtgactt gccagtaacc
    83761 tttaacgtcc aaactaacta ggcatgttat aatttaccag acacggtctc ccgtatttca
    83821 tttgtaggtt gaatttaaaa aagccttatc gtatgtttca ggatttcata ttattattat
    83881 ataataaatt ttgaattttt taaagtggtt ttatatagta attgagataa tcttattcta
    83941 tcattacttt ttcttccttt tttctttatg tatttagtta attatcgttt tttcttagct
    84001 ctagttttag tatttttttc attataattg tattcggatt cttgctcatt aatgttgtat
    84061 agttcctcat cgtatactat atcttcatca ttttctatat tttcatagcc tgtgttctta
    84121 tcttctacta attcatcttc attatcctcc atttcacctt catctgttaa ctcatcatca
    84181 tccaattctt tgtcttcaca atctaattct tcgtcttcat aatttaactc atcattattg
    84241 tcttcatcat cattattact atcatcacct cttaaaagac ttcctaacaa tttgagatta
    84301 ttcatactac caagattgtt tatatttgcc aaagagctca aactaaatcc accttcacca
    84361 aagtcatctg gtaaaaataa ttctgcaaat aaatctatct tctttttcat tcctatagct
    84421 ttttcaactg aattttttct tttttctggg aatacatcta taatttcctt tatcatcata
    84481 ttctttttat catcactatc catttttctg aaaaaatccg tttcatcttc tgtatctacc
    84541 atatctatat tatttaattt ttttattcct ctaactaaat ctaaaacact ttctattttt
    84601 attagtattt ttctttcatc tcttgacatg tattttttag ttcttgttat tatttccatt
    84661 cccatttcta aatcttcttc acttaaatcc atgagcctta aacctctttt tatatcattt
    84721 gcatcaaacc ttaaattgcc atgtgtagac tgtgaaagtt tatcatttgc attttttttg
    84781 ttttttctaa ctctattatt tccttttgat ttatttttat catcaaatat agagatatta
    84841 ccattactca atgcaatcac tccaatcaaa aatagtaagt tattcaagac aattccccct
    84901 tatattatat aattgcccta tattaaagta tgtttttcat attttaatgt tccattttta
    84961 aagctcagtg catatatatt atctataaga atttttattt atattatata tcactcacaa
    85021 ttcaccactt caatattatt tctatatata aatagtatga atataattca atatatattt
    85081 atagaaaggg gtttttttat gaaaaaatta gatacagagt cattagaaaa aatggctaaa
    85141 caaaaaaata ttgacaagga taaaatagaa aagatggctg atagttacaa aggaaaatca
    85201 gaaaatgaac ttatggagga acttataaaa ataggtaaga acctagatgg cagagatgaa
    85261 gtagtatcaa aattcaaagc atttttagat gaaaatcaac gcaaaaaact ggataatata
    85321 atggaaaaaa tctcagacgc agaaaaccaa agagatacta aaccagctaa aactaagaag
    85381 gctaaaccta ctaaaggtaa gtcaaattca cctgcgccaa aaaatacacc aggtagtcaa
    85441 caaaaaaaat ctaaaagttt atttaagaaa actaaaaagt ctaaccctca tgaatagata
    85501 aaaataaact atttaagtaa ttagataatt atttttagtt aatctattat taaatttgat
    85561 attattgaca taaaaaatca ggtagtgcct taggcactac ctgattgact ttaatagttt
    85621 tatttttttc tttctgtgac actttctcta tcaacaattc tataaggtaa ttctattttc
    85681 ttattttcaa ttaattcctt atttattaat tttataacca ttcttattgc tactgctccc
    85741 atatcgtata gaggttgata tactgtagta agtttaggtc tatacattct agctatctta
    85801 acatcattaa atcctgcaac agatatgtct tctggaacct tatatccagc atcacatata
    85861 gcatttatag cacctatggc agcctcatca cctgttacaa aagccgcatg aggtattatt
    85921 ccatcatcta atagttcttt catactattg tatccactct cataatcagt tccaccatac
    85981 ttaatcaaac tcttgtctaa ttctatattg ttatttgaaa gtgctttctc ataaccagca
    86041 agtctttcca tttctaaaac agtatcatct ttactcgtca ttataaaagc tatcttttca
    86101 tgacctttct ttataagatg ctctgtcata tcaaaagtag cttcttcgtt gctagtactt
    86161 actgtatata tatcataatt tctagcagtt ttacttatat atgtcgctgg tattccacaa
    86221 ttttgtatat agttgatatg ttcttgttca actatccatg aaatcataac tataccttcc
    86281 acttgttttg ctctcaatag atttatactc ttaagttctt gttccttatc agagtatgta
    86341 ttcgctaaaa gaatatcata gtcatacatt ttagcaacct cttctatccc atttaacacc
    86401 tcattaacaa aagaatctga aacttctgga actattaccc ctattaattg actcttcttt
    86461 gttactaagc ttctagcaag tggatttggt atatatccag tctcttttat aacctctaaa
    86521 actttttgtt tgacttcatc agttacaggt tttgaatcat ttataactct agatacagta
    86581 gatattgaca ctcctgcttg tttagcaaca tcttttatcg ttatattgcc tttcatcttc
    86641 atcctcctta ttttactaaa tttatctaaa actgaaccaa atttttgaag gttcctattt
    86701 taactacatt tatataagtt tttattttac cataaaagca agtacattta aatacattat
    86761 attttatatt ataccctata ttcaacaaat ttaataatat tcattcttaa tttaaatcat
    86821 attaaaaaat aaaataaaaa aatgctggta taaaatacca gcattttttt attctaatga
    86881 tttaagtatt agcagccgca acctacttca ccatcaaaga atccaccaca tgaacaagtt
    86941 attagcaata atattaagaa aggtatccat gacattatgt caatgtctct ccagcaatct
    87001 tcaaaagcta agaataggaa gaatagtact attatccacc atcctcctcc accaaagcct
    87061 ccttcttctc caaaaaatct atctaacata acaaagccct ccttttttta ataactgtgt
    87121 tcttattcta agcatccacc acagcagcaa agtattaata aaactattag gaatggtatc
    87181 catgccatta tgtcaaattc tgcccagcta tctccaaaag ctaagaatag gaagaatagt
    87241 actattatcc accatcctcc tccaccaaaa catccttctt ctccaaagaa tctatctaac
    87301 attatacgtt acctcctgtt gatattttgt tgagcttttc gctcctaaca tatactatgc
    87361 atttggtttc cattttgcta atgtattttt actatttttt taaatttttt aatttgaact
    87421 aaaaaaggta aaaccataac ttgtataagt tactggtttt acctatttaa taatcaatat
    87481 tttttagcaa caacaaccat catcgaagtt aaataataac aatactatta atataaccca
    87541 tatccatata ttgtcatcgc ataataagtc ttctaaaatg tctgtgcata atagtaagaa
    87601 tactataact attattatca acattttatt cccaaaaaat ccttcgcatc ctccaaagaa
    87661 acgttccata ttgtcttcta attttgtcat aactaatcct ccttgaatca ttaagagact
    87721 aagttttgtc tctttaatta aatatatgta gtaatagaca gataagttac ttctaaaaag
    87781 tttttattga ttagtttatt tatttctttt tcaccaagtt tattgtatct atcaacttca
    87841 tccagataat cttttttctc ctctgatata gtatagatta aactttctat tgattttatt
    87901 ttgtactcct tatatctttc tatcaagaag gatgtttttg aattttctat tcctttcttt
    87961 acatgcatta accttgatat gtagtcttct ttttcattag atacataact ctccttttca
    88021 gctacatctt caaggattaa attggtctcc attacataat cctctatacg ttgcatatct
    88081 aaagttattg aattataata aaaatttact gctataagta aaaacattcc tactgaagtt
    88141 agtaatagtc ctacatattt catagcattt cctcctaagt tatatttgtt atcaataaag
    88201 tttattcatc aaataatact ttattactac atttataaaa ttttattatt ttttatagat
    88261 tccatattga aaaattcttg atattatatt aaactaacat taaaattaat taaaactgct
    88321 ttaggaggct taaaatgttt gagaaaataa aagaaataat agcagaacaa ttaggggtag
    88381 acaatttaga tgagataact atggaagcat ctttaatgga cgacttagaa gctgattcat
    88441 tagatgctgt tgaaattata atggcccttg aagatgaatt tggaatagaa ataccagacg
    88501 aggaagctga gaactttaaa tgtattggtg atatatgtaa atatatcgaa gaaaacaaat
    88561 agtatcgttt tgtctacaaa tataaatagt ctgtgtaaac ttctacataa taaattatat
    88621 tagagttcgc acagactaga ttacatttat ttacaatata taaaatacac gctcttatat
    88681 ttaatttata tactaagtat ataaattact tttcttcata aaatgtaaca ttctttatta
    88741 ttatatctat agttccatct tgattttgtt ttacagtata cttcattggg tcttcaaaat
    88801 cagttagatt cccttttatg tcaaaaccat tatccgtttt tatacttctt tttttaagct
    88861 ttttctcaac ccatttttta tctatactaa aactttcatc aagacctttt tcttccatat
    88921 gctctttaaa gctatccttt aactcatcat ctttaattga attatcaaca aagtcattta
    88981 tatcaacttc atgtttttcc ttcagtgtat aatttaatat acttcttaca tcttcagctt
    89041 gctttatatc attactaaga gcattggtta tccaattttc agctgtattt ttaaatacct
    89101 tggtcttgta cttatcatca tctatttttt tagcatttaa aaattctgtt acaaacttag
    89161 attctgaccc ttctttttca gcatccttat ctaaaagcct tagatgaaac tcatcattta
    89221 taccacttag actaatcaaa gctccttgct tttgtcttaa agtctctggg ataccaattt
    89281 catttgaaac catttgaata ttaaatttat catccacaaa ttcaattgaa tgagtgtaca
    89341 actttttata atctaatttc agtattgcta cactcttttc atctttaata gtatataagc
    89401 aaattgccaa atcacaagat tctagtgcag cattaatttt cataacatca aacaagtaag
    89461 atgcaatttc tttagaattt ttcaaaaaag tactttcatc atatattatt tgttcacaac
    89521 agtttttaat taaattgtca ttataatctt taaaaacacc ttttcttaaa tcctcatctt
    89581 ttgcaattct ttttatagct ttctggaaaa aaccatccac ttcttgatta actttgcctt
    89641 caaagtcatt taatattgga acatcactat ttttgtccaa aacatgtatt ataaatttat
    89701 gtattatcat atatatcacc ccattatctt aatttcgata ttaactcttt catatcctct
    89761 ggtatatctg ctttaaattt caatttttct tttgttcttg gttgttcaaa ctctaactta
    89821 tatgcatgaa gtgcttgcct atttattagc tcttcatcta cataaccata caactcatca
    89881 cctattattc catgacctat atgagccata tgtactctta tttgatgtgt tctaccagtt
    89941 tctaagctta cttctaatac agttgcattt tctagtcttt ctattacttt atagtgagta
    90001 acagatgact gtcctctttc atctattatc ctctttattg aatcttctgt aggtctataa
    90061 attggctcat ctatagttcc ctcattttct tttataattc catcaactac tgttatatac
    90121 tttttttcaa ctttattttc actcattgct gtagacaaag tatgatgtgc ataagcattt
    90181 tttgctacta taactaaccc tgaagtattc atatctaacc tatttacaaa tcttattttt
    90241 acattttctt tttgattatc tatatagtaa ctaataccat ttgctattgt tttatcatag
    90301 tggctttttg ttgggtgaac taccataaac ggaggtttat tcaccataat tatatcaaaa
    90361 tcatcataaa ttatctgtaa atttaaatct tgaggttcaa aatttgcttt ttcctcgtct
    90421 atttttactt ctattaaatc accactatac acctttaaac ttggtttttt atatactcca
    90481 tttactaaaa cactcttttc cctcttcatt tttgataatg acctaactga gaaatttagc
    90541 ttgtccaata aaacttcttt taaagtcatt tcttcttcat ttgtatacga tataagatta
    90601 tatctttgat tctctttttt aaacaaactt ttacctactt tcttttatat cttcctactt
    90661 tttatatctt caaaatcatg atattatata ttttacacta tttttgttta atagataata
    90721 attattttta actataaaaa cctgtaagaa taacaaatag ttattcttac aggttaaatt
    90781 cataattaaa tatttaattt gtaaatatta taatctaaaa ctatctctta actattaaag
    90841 tagttcccat tccaccgcct atacaaagtg tagcaagacc agttttagca tctcttctct
    90901 tcatttcata taaaagtgta gtaagtattc ttgctcctga gcatcctatt ggatgtccta
    90961 tagctattgc tccaccatta acattaactt tattcatatc tatatttaag tctcttatta
    91021 cagctacaga ttgggcagca aatgcctcat tagcttcaac taaatctata tcttcaatag
    91081 tcatattagc agcttctaaa gcttttttag ttgctggaac tggtccatat cccattattt
    91141 tagggtcaac accagctgtt ccataagaaa ctatagttgc aagaggctct attcctagtt
    91201 cttcagcttt ttctttagcc attactacta gcatagcagc accatcattt attcctgatg
    91261 cattaccagc agtaactgtt ccatcttttt taaatgcagg tcttaactta gcaagtttct
    91321 ccattgtagt gccaggctta atatattcat ctttatctac tacagtgtca ccttttcttc
    91381 cttttataac aacaggaact atttcttcat caaattttcc ttcagcttga gctttttcag
    91441 ctttattttg acttgcaaga gctaattcat cttgttcttc tctagttata ttccattgct
    91501 ctgctatgtt ttcagcagta atacccatgt gatagttatt aaatatgtct gataatccat
    91561 cttttatcat tgaatcaaca aaagcagcat cacccattct tgcaccatat ctcgcacttg
    91621 gtactaaata aggagacata ctcatgtttt cagctccacc aactaacatt atatcagcat
    91681 cacctaatgc tataagttga gatgccattg aaacagatct taatccagaa ccacaaacta
    91741 tatttatagt catagctggt ttttctactg gtattcctgc tcctaatgct atttgtcttg
    91801 ctatattttg tccaagacct gctgtaagta ctccccctaa aagagattca tctatcatat
    91861 ctggagttat gttagctctt tttatagctt ctttagctgc tgttacccct aactctaccg
    91921 ctgaaactga tttaaatgct cctccaaaac ttcctactgc tgttctagct gcactggcaa
    91981 ttactacttc tctcatattc attaccccca ttaaattaga tttttcatat atccgaaatt
    92041 gttttttaaa caattttatt taaactttta attcccaaat tcttatttat tataatcata
    92101 gaatcctatc ttagtttttc ttcctaattg attagctcta accattttag ctaaaagtgg
    92161 atgaggtcta tatttagtat ctccaaattc agtatataaa acgttcatta tagctaaaac
    92221 aacatctaat ccgattaaat cacctaatgc tagtggtccc attggatggt ttgctcctaa
    92281 tttcatagct tcatctattt cttctttact tgcaacacca tctgcatata taccaacagc
    92341 ttcatttatc ataggtataa gtattctatt tactacaaat ccaggagatt cagatacatc
    92401 tactggtact ttattgatac tcttagataa ttcaaatact gtatcaaaag taacttttga
    92461 tgttaactga ccacttataa cttcaactaa tttcatcata ggaactggat taaagaaatg
    92521 cattcctata actttatctg gtctcttagt agaagaagct atttctgtta tagataatga
    92581 tgaagtattt gttgccaaga tagtatcttc tttacataat tcatctagta acttgaaaac
    92641 atctttcttt atattcatgt cttctacaga tgcttctatt attaaatcca tatcttttaa
    92701 atcttcataa ttagtagttg aactaacatg acttaatatt tctgcttttg tagcttcatc
    92761 catttttccc ttagtaacta acttagttaa atttttatct aataaagcta aacatttatc
    92821 tatagcacct tgagttctac tctttaaaca tacatcatgt ccacaacttg caaaagtttg
    92881 tacaatacca cttcccatag ttccactacc tattacagct aatttcatag ttataacctc
    92941 ctgttatttt agtatttata ttctgttaac tagattaaaa tactatttaa tctagttaac
    93001 agcaaatata tttttaatta gatttttacc cttttataaa gttagcttct ctcttttcaa
    93061 cgaaagctga cattccttct ttttggtctt tagttgaaaa acaaagacca aataaattag
    93121 attctatatc tattccagta tttatatcag tttgagcacc aagttgtatt gcttctttag
    93181 agtatctaac tgcaagctga gcatttttag ctattatctt agctaatttc tcaacttctt
    93241 ctattaaaat gtctggctca acgactctat ttactagccc tattttttca gcttcatcag
    93301 cttttataac ttgacctgta aagattaatt cttttgcttt tgccattcca accaatcttg
    93361 taagcctttg agttcctcca tatcctggag ttattccaag agttacttct ggctgaccaa
    93421 atttagcttt agcagatgca attcttatat cacatgccat tgcaagttca catcctccac
    93481 ctaaagcaaa tccgtttaca gcagctatca ctactttttt actattttct atttctccaa
    93541 aagcttttgc tcctaagata ctaaaatctt tagcagctac agcatctaaa tctttcatgt
    93601 atgcaatatc tgctccagct acaaatgcct ttccttcccc tgtcaatatt acaacatcaa
    93661 tagtttcatc attattaata tctacaaata cttcataaag ttcttctaaa gtctttgaat
    93721 ttattgcatt aagggcttta ggtctattca ttttcactgt acatatattt ccatctactt
    93781 caacagctac attctcataa actttaacat cacttgtact cataataccc tccccaagaa
    93841 attagttagc taaaacttca cctttttctt ttgcaacact taactgactg ataagttctg
    93901 gaagcacttt atgaacatct ccaactatac caacatcagc atatttaaat attggagctt
    93961 ctggattttt atttatagca actataaact cagcatcttc cataccagct atatgttgta
    94021 ttgctccaga tataccacat gctatataaa ggtctggtct tacagtttta ccagtttgac
    94081 caacttgtct tgctttatct aaccaacctg catctatagt ggcacgagaa ccagaaactt
    94141 ctccacctat aatttcagct aattcataaa gtatgtctaa gttttctttt ccacccattc
    94201 cacgtccagc agaaactaat atcttagcat cttctatttt aacttgtttt ttagcttctt
    94261 ttattacttg tacaacttga actaatttat cagcatcatt aaattctacc ttgaaacggt
    94321 taattacagc ttctttagtt tcatcaggtt catttttctt cataacccct ggtctaactg
    94381 tagacatttg aggtctgaaa tctttacaaa ctattgttgc cattatattt ccaccaaagg
    94441 caggtcttgt cattaataat aattttgtat cttcagctac tgcaagacct gtacagtcag
    94501 cagtaagacc tgtatgtatt ctagcagaaa ctctaggcgc taaatctcta cctattgaag
    94561 ttgcaccaaa taatacaact atagggtcag ctgcttttat tgcttcataa gctgcttttg
    94621 tatatggttc agttgtatac actgctaaag cttcatcatc tactactatt acctcatctg
    94681 caccatagtg tgctaatgta tctattaaac cttctacctt actacctaaa agtaatgcag
    94741 aaacttttgt atcataatct tttgctattt ctgtagcctt tcctagtaat tctaaagaaa
    94801 cagtttgaat tacattttct ctttgttcta ttactactaa aacgttaccc attctttatc
    94861 cccccttaaa ttatatgata tacttctctt ttaatttatc tatgataatt ccagctgatg
    94921 ttttcgcatc ttcattgtat attgtaccag ctggtttaac tgattttgta aatgatttaa
    94981 atacactagt tggagaacct ttaagaccta aattagaagg gtcaacttct atatctttta
    95041 cagtccatgt ttctactaca tcattttcga aagcatcata tattcttcca actttcatgt
    95101 atcttggtgt gttcatatct ttaagagttg ttataaggca tggcatttta acttttaagt
    95161 catggcaaca atcttcaaat tgtcttttta ctaatacata ttcaccttca gtttttattt
    95221 cttcagcata tgttattgat ggaagattta aatgttcagc tatttgaggt ccaacttgtg
    95281 cagtatctcc atctatcgcc tgtcttccag ctattataat atcaaaatct atatttttta
    95341 atgctcctgc taatgctgat gaagttgccc aagtatcagc acctgcaaat gctctatctg
    95401 ttaataatat acctctatct gcacccattg ctaaagcttc ttttaaagcc atatctgctt
    95461 gaggaggtcc cattgttata acagttacat gagcacccat ttcttctttt aattttatag
    95521 cttcttctaa acctgcttta tcatcagggt ttattatact tggtactcca tctctaatta
    95581 aagtacctgt attaggatct agtttaactt ctgttgtatc tggaacttgt tttatacaaa
    95641 cgactatatt cataaatcct tcctccatat ctattttaat atcgacctat tgtgtatatt
    95701 ttaatattta tctattttaa tagttttcct gaaataacca ttctttgaac ttcactagtt
    95761 ccttcatata tttcagttat cttagcatct ctcatcattc tttctactgg atagtcacga
    95821 gtgtatccat atcctccatg aagttgtaca gcttttgtag taacttccat agctgtttca
    95881 gctgcaaata attttgccat tgctgcttct actccataag gttttcctaa gtctttattt
    95941 atagctgctt gatatacaag gtgtctagcc gcttgtacct taacttccat atcagctaat
    96001 tggaattgtg tattttggaa ttttgataat ggtctaccaa attgtactct ttcttttaca
    96061 tatttaacag tttcatcaag agcaccttgt gctaaaccta aagcttgtgc agctatacca
    96121 attctaccac catcaagagt agacattgct atcttaaatc cttgaccttc ttttccaagt
    96181 aaattttctt taggtattct gcaatcctca aatattaatt cactcgtagc tgaacctctt
    96241 atacccattt tcttttcttt aactccaaag ctaaacccag gagttccttt ttcaactata
    96301 aatgctgata ttcctttgtt ccccttagat ttatcagtca ttgccattac tacatatatg
    96361 tcaccagcta ttgcgtttgt tataaatatt tttgagccat taagtatgta ttcatccccg
    96421 tctaaaacag cagttgtttg ttggccagac gcatctgtac cagcattagg ctcagtaaga
    96481 ccaaatgctc ctaatttttc tccacttgct agtggtctta agaatttttg tttttgttct
    96541 tcattaccat attgatatat aggccatgag ccaagagatg tatgagctga taatataact
    96601 cctgtagtac cacaaactct agacaattct tcaactgcca ttatatatcc tacagtgtct
    96661 ccaccttctc caccatattc ttttggatat ggtataccca tcattcctgc ttttgccatt
    96721 ttttccactg tttcataagg aaatctttct tcttcatcaa gttctgttgc taaaggttta
    96781 acttcatttt cagcgaagct tacatatagc tctttaagca tctgatattt tttagaattt
    96841 aaatccataa tagcctcctc agtattttat aaatatttta ttttcattta ttaattaaaa
    96901 tctcggcaac atctataata aggtatttga atatacgtcg agaaatttat aaccttaatc
    96961 aaactacgct ctatatttat atgtgattat actaaccaat tatgacatta atttaatcat
    97021 aaattgttaa tttaaaatca actatactta aaaaaaatct cgctttttgg aattttgtga
    97081 aatttcaagt tagaataaga tttctttcac actggttaga gataaaataa tttgtttacg
    97141 atatttatat tagggtatat taaacattaa atattgtctg tacatctgtt ttttagccat
    97201 gtacagaaga tttttatcgt ataaaaatta ttttaataga gctaaataat catattttta
    97261 tctgactatt ttttattttt aaatatctta catctataat agtatcactc aaaggataat
    97321 ttttcaataa tttctaatta tttttttaac aatatttatt acattttttc cacttttttg
    97381 tcattttttt attgtttcga aaaaaaatca gaatttttta actttatttt ggattattag
    97441 tttaaattag attttcctct tagatttata aatatttaca caaaaaaact acctctgtat
    97501 agattgtata cagaggtagt tttttactaa ttcctactat agtttactat atttttttac
    97561 caattcttac aaacatctac ccatttttca cacttagaaa acttctccat ttcttcacat
    97621 gtaagttcta ttgcagagtt actactgcca catgcaggaa atactgtatc aaatcttttc
    97681 attgaatcat ctaaatagac ttttatagaa ttttttaaac caaatggaca gactccacca
    97741 atagcatgtc cagtaaactc caagacttct tctggtgtca acattttagc cttacaatta
    97801 aattcagcct tatacttctt attatcaatc ttagcatcac cagctgtcac aattaaaatt
    97861 gcatcatctc ctattttaaa tgagagtgtc ttagctattc ttgctggaat aaccccagct
    97921 gcttcagctg caagttccac agtagcacta gattgttcaa attctaagat actgtcttcc
    97981 ttgccaaatt gtttaaaata ctctcttaca ttacttattg acattaaata cccctcctag
    98041 tctgaacttt tataaatttc atattattct taattatatc tataattgat ttatttttca
    98101 aattattcca taatattagc attccatgta tcattatttt ttccaactac tagataaagt
    98161 ccttttgcca ttggaatatt gacaatatat tctcctttat actctacact cataccagat
    98221 tcattaaagt acctataatc aaaatttagt ccttttggaa ttacaaaatc aacataacct
    98281 tgattatttg gttttattcc atatttcaga gttctttcag ttatagaatt tttttcatta
    98341 aataaatcta catttacata tgcagaacac ttattcattc cctttttatt ttccacacaa
    98401 ttttcaaact tcattttagc actgtttaat ttataactat atttactatt attgcttatt
    98461 ttaaatctta caatagtacc aacatctcta cttctcctgc tatcaaaatc aaaaacaatt
    98521 tcctctaaat gatttatttc ataatctttg acacttacca tatctctata tactaattta
    98581 tttatagcta tgaatagtgt aaaaatcccc aaaataaaaa atgaaacttt tataaacttc
    98641 ttcattttta gtctccttat attttgtgct attgtgctat aatattaatc aaaattttaa
    98701 taattaaact tattcttttt tgaaatctta atagaaaaat acattgatat tataaaaatt
    98761 attattgtta aaaatgtcat actatataaa tttatatact tagtattagc tatatcagtt
    98821 acataatttg aaagatatac tcctccaact ttactataat taaaatgctt tacttgatat
    98881 acaatcatac taatcatctt caaaagactt ccatatacaa agtaaattaa aatacttact
    98941 ataaaaccac aaactttcat ttttccatat ccaaacttaa aaattaaagg cagtaaaatc
    99001 gtcaaaattg ctaaaaatat atttacagaa aaaaatacat catttaaaac catatttcta
    99061 aagaacacta gtgatgtcaa tttacttagt aaggacacaa ttattgttac agaaattatt
    99121 aatcctacac ctaataaata ttttgagtaa actatatctt ctatactaac tggcatactc
    99181 cttataaaaa tccttgaatc attttcataa tcacactcaa acgtatttat aaatatcaaa
    99241 taactaacaa caatacttac tgtataatat gaaattgaat taaggaaaaa ataaaacaca
    99301 aaaaatagca atatgtactt taaattacgg ataccatctg aactaatccc tattattaaa
    99361 tcttttctta ttaaattgaa catcatctca cctcatttac ataataatac attagttctt
    99421 ctatagtagg atttttgacc ttatgcttat caatttctat caataggctt tttactttca
    99481 agctatctcc aactttaaca agtgcctcat tataatattt atactctttc acaccaacta
    99541 tgctttcttt aattgcttct aactctgctt tatttgccct aattatctta tattcttgtt
    99601 ctattaattc tttcttaaca gtaaaaatct gatttcctct atttataaaa acaagataat
    99661 cggcaatttt aattaaatta tcagtattat gagtagaaat tattacacta ctacttccat
    99721 ttttcacaaa atcttgtaag tactgcatta tttcagttct tacaattggg tctatcccag
    99781 cagttggttc atccaaaatc aataacttag cattgtgact aagtgcactt gataacataa
    99841 gcttttcaga ttgaccttta gataaatttt caatatgcat attttcttct atatcaaact
    99901 tattaaggta ttcatcaaac ctttctctat caaaattctt ataaaataaa gaaactattt
    99961 ttctaaattc cttaaccttt aaatgcggat aaaattgtaa agaatcatat acaaaaccaa
   100021 tattgttttt aaaacttatt ggagaatttt caatagtttc attacaaagt tcaatttcac
   100081 cttcatctgc atcaataatc cccattataa tttttattaa agtcgttttt cccgaaccat
   100141 ttggtcctat aatcccaaca atatcccctt cctttaactc taagtttata ttatttaact
   100201 tgaattttcc taattttttt gtgatattcc ttatgctaaa cacatcttca cctcttatgc
   100261 atttttttat acccacctat acatatttta acacattcat tacaaaggtc atttataaat
   100321 ttataaatta agaattataa aactatgtta taatacaaag tatgaagagg tgaatatatg
   100381 aaaagaatta taactataaa tacaaaccaa ttaaataagt cccttgagac taaagaactc
   100441 ttaactagaa aacttatcaa tgctggcttt gaagtgtatt cagatattta tccagacaca
   100501 gagcttatta tatcaattgg tggtgatggc tcttttttaa gaacagttag agatttcgat
   100561 tttcctgaga ttcccataat gggaataaat acaggtcatc tggggttttt tcctgatatt
   100621 ttaccagata agattgatag ctttattgaa gcttatacaa aaaaagatta tattattcaa
   100681 gaaatgtcac ttcttaatgc ggaagtatat acaactacta gtggttctaa tatgcttgct
   100741 gtaaatgagg ttgttataag aggagacaag tctaggacta tacacctaaa tttaagcctt
   100801 gataataaac atatacaaaa ttttagtgga gatggtatga ttatttctac ttccacaggt
   100861 tcaacagcct ataactattc tgctggaggt agtattgttg atataaatct tgaacttatg
   100921 cagattacac ctttacatcc gataaatacc aatgcatata ggtgctttac atcaagtata
   100981 atatgttcaa atgaatctgt tataaagatt gcaccagaat atagatttga agattctgta
   101041 ttgattgtcg ttgatggagt tgagcacaga tttagacaaa tcgaaaatat aaaagttagt
   101101 atatctgatg caaaaataaa attacttaga atgtcaaact atgagttttg gcatagagta
   101161 tctgaaaaat ttttatagac tgtacttagg aggattttta atatgaaaat aggaataatg
   101221 agtgatactc atggtagctt actttacttt gaaaaagcgt taaatgtatt atctgattgt
   101281 gatgttttat tacatggtgg agatgtctta tatcatggac ctagaaatga tattccagaa
   101341 ggatataatc ctaaaaaatt tattgagaca ttaaataaat tagaaaacat tgtgattgta
   101401 aaagggaact gtgatgcaga tgttgaccag atggttatag aacatcctat tcagagtcct
   101461 tatgtcatga gccaatttgg tgaaattaga attatattga atcatggtta tatagaatca
   101521 gaagaagaaa ttattgacaa agcaaagaaa atgggtggtg acatattagt tttaggacat
   101581 actcatgtaa aaaagctata catggatgat aatttaatag taataaatcc aggaagtact
   101641 tctatcccaa aagatggaag ccattctgtc gcaattatag atatcataaa aactgatgat
   101701 gaggatgagc ttgaacttga tataaactta attgacatca atactggaaa tataataaat
   101761 atcaatgatt agtaaatttt taataaaaat aaaataagct ttaatttatt aaactcataa
   101821 taaaaacaag taaaccattt tatttctatc tcaattagaa gtttaagtac aataccttaa
   101881 acttctaatt aaatagaatc tggtttactt gttttattat atgctatatt gaaatataac
   101941 ttagtttact tgtttct
//
LOCUS       DAMJXI010000007        88521 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.007, whole genome shotgun sequence.
ACCESSION   DAMJXI010000007 DAMJXI010000000
VERSION     DAMJXI010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 88521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 88521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..88521
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.007"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            215..874
                     /gene="cprR"
                     /locus_tag="PC465_000755"
     CDS             215..874
                     /gene="cprR"
                     /locus_tag="PC465_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CprR"
                     /protein_id="HDF2648083.1"
                     /translation="MSKILVVDDELDMLKLIENVLKRDGHEVKVISDVEKAMNMDFNY
                     FNLIILDVMMPKMDGFEVCKTIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPF
                     GVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVSIDGKKINFTKSEYLICEFL
                     AKNKGQVFSKERIYESVYGFDGESDISTITEHIKNIRSKLKQYDIYTIETVWGIGYKW
                     V"
     gene            1085..2143
                     /locus_tag="PC465_000756"
     CDS             1085..2143
                     /locus_tag="PC465_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDF2648084.1"
                     /translation="MDRLKNIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMV
                     DKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASG
                     SQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMP
                     LVFLGIAINSFVLIMIILVILNPKKIKYFMRITIKHLSKIKFLKFLDNKIESIESFID
                     DYSKAINFFAKNKKVLISTIIVTFIQLSAYFSVSFWIYKAFNLQGYSYIYILTLQAFL
                     YMAISPIPTPGNVGANELAFFTIFKSVFPQPLMGYAVFLYGGFMYYLILIGSGIFTVI
                     THYRMKNRIGRNIVLSEN"
     gene            2394..4538
                     /gene="fdhF"
                     /locus_tag="PC465_000757"
     CDS             2394..4538
                     /gene="fdhF"
                     /locus_tag="PC465_000757"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:2808..2810,aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HDF2648085.1"
                     /translation="MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCL
                     KGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYTASRLNEIKEKYGPDSI
                     MGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSI
                     PEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIK
                     GGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEEL
                     IRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQ
                     NNVQGACDMGALPNVYPGYQNVTDDKIREKFEKAWGVKLSPNNGYSLTQVPDLVLKEK
                     KLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEH
                     EGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLC
                     PSFLGATYEKIETQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPM
                     EVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAEKLGIEDDE
                     LVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCA
                     VKLEKLEDQELAEKCVREEYQSLKDKMTATNI"
     gene            4587..5420
                     /gene="fdhD"
                     /locus_tag="PC465_000758"
     CDS             4587..5420
                     /gene="fdhD"
                     /locus_tag="PC465_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HDF2648086.1"
                     /translation="MNNIYSKTKLQENSKDKVFENSYSLVDYKYLNSFNVEVSKINEH
                     EVSIDNEEIIAEYPLSFILNDKYINTFLCTPYNLEELIVGFLKTKGYIENKKSLLKFE
                     INESERFAKVTIQEKQKNQDEQIIFLNSLDYITCAPVKSNIKINYDTIYSIMDKNLNS
                     SELFKNTGGVHSVSVFNFDKKIVTCEDVARHNAMDKAIGFCVLNDITLKDKIVAVSGR
                     ISLEMILKAAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIK
                     K"
     gene            5431..5604
                     /locus_tag="PC465_000759"
     CDS             5431..5604
                     /locus_tag="PC465_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648087.1"
                     /translation="MCTKKEEQRYSKCEICGVLIDDTDKVYNNTYNLCKKCKRNISTE
                     KIVKYINIYDENN"
     gene            5641..6192
                     /locus_tag="PC465_000760"
     CDS             5641..6192
                     /locus_tag="PC465_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2648088.1"
                     /translation="MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVD
                     IPVIPRLYLVKGDNFCMPIQCRHCEDAPCLNSCPQKAIVKENNIMSVNEEKCIGCKTC
                     LLACPFGAIDLLPQYEDGKEVEQVILDENKKIAYKCDLCKDNEKIACISACPQEALKL
                     VTPIDDKKAKNRQAALSLLLTNK"
     gene            6217..7593
                     /locus_tag="PC465_000761"
     CDS             6217..7593
                     /locus_tag="PC465_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HDF2648089.1"
                     /translation="MIINIDKDLCTGCRECSKVCPVNAIEGEEGKPQEINLDRCVMCG
                     QCVQTCKSYASVIDEGFEFLQEKKQEREIPESINEPIFAAYNVCDIDKVKKALSDPNV
                     FTMVQCAPAVRVALGEDFGYYLGYLGAGKMAAALRALNFDRVYDTNFAADLTIMEEGS
                     ELIKRVTEGGTLPMFTSCCPAWVKFMEKNYPKLTNHLSSCKSPQQMGGAIFKTYGAEI
                     NNVDASKIFSVSIMPCTCKKYECDREEMDSSGYRDVDVVLTTRELAYLIKDMGIDFKN
                     LREEKFDSPLGSYSGAGTIFGVTGGVMEAAIRTGYELITGESIPDVEVKQVRGENGFR
                     KSTIKIGDLDLRVGVVSGLKNVIPVLEDLEKGKLDVDFIEVMTCPVGCVSGGGQPKIL
                     LEEYKELAYENRTKATYVHDEHLAIRKSHENPDIKKLYDEYLVEPLGEKSHHLLHTTY
                     CIGKEVAK"
     gene            7593..8108
                     /locus_tag="PC465_000762"
     CDS             7593..8108
                     /locus_tag="PC465_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2648090.1"
                     /translation="MNYFVIADPDKCIGCRTCMIGCVVAHSDEDIFYQNPDEINFNPK
                     LSVIKTKEVSAPIQCRHCEDAPCAKACPNGGIVRVGNTIKINEENCIGCKTCMLACPI
                     GAIDIVTLKDVDEGKLCFRERMTANKCDFCIESPEGPACVNVCPTKAFTIVKDEDIDS
                     KVKNKRKLAIL"
     gene            complement(8186..9469)
                     /locus_tag="PC465_000763"
     CDS             complement(8186..9469)
                     /locus_tag="PC465_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugated bile salt MFS transporter"
                     /protein_id="HDF2648091.1"
                     /translation="MNTLLNNKFSIKNFSNAWVIVLGCMLIQAVPFSIVASIQPQFIS
                     YVVEGEGFSLASFSLIFTIGTIASAIASPFIGVLFSKVNIKILYLLGCIISSIAFATF
                     SICTELWQFYTVSCIVQIGATIISAIGIPVLISAWFDEESKGKALGFAFAGGSIGSIF
                     LQPLAVRLLATQGYSRSYLIFGIIALIVGIPVILFILRMPKDINEKVKSKGKKEKASD
                     KISPSVWGYTLKEAKKIKYFWIMTIGFIFVGIYVSSLSVQYPTYLRNYLNPILIGTVG
                     STFALFALIGNLFGGLLFDKFGQTKPLIISFVLVLIATLSLLLVDKSSTFAFVFAILK
                     GLSVFAYMIGPAYLTGSFFGQKEFGSIYGIVQLIFAVGFALGSTLFGLLVDNFGYRFS
                     WSIIILSVIIAYTLLIITSIGMKKLNKERLDKLMQ"
     gene            9657..10079
                     /locus_tag="PC465_000764"
     CDS             9657..10079
                     /locus_tag="PC465_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HDF2648092.1"
                     /translation="MSFEKINNNNLDKIHNRKCIMLVNFNKKELSLIKNVSNFAGIRD
                     HIILSDKNGENIIRDILDGNISNECENGIKSKSVIFNNTPSTQVNAFLEGLKKVRINR
                     PFTAMVTETSIDWTLNNLIENLVQERNAMSLGKTIEHK"
     gene            10181..11119
                     /locus_tag="PC465_000765"
     CDS             10181..11119
                     /locus_tag="PC465_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HDF2648093.1"
                     /translation="MKVLFTINYGKEKFDKIRELGYDVIHYSEDSIENNEDVNTADVL
                     VTYNPFERLDISKMKNLQYIQTTSVGIDQLPKEEVLKRNIKIANNRGGYSVPIGESIV
                     LYILEIYKNSAKFFKQQQNKEWKMDFSVSELYGQRVGFLGTGTISSEAAKRLKAFGVE
                     IWGVNTDGSSKKYFDKCFATEDMNIVFEECDIVVVAMPSTKSTDGIVNKDMFKLMKDG
                     SVFINVGRGNTVNQKDLEECVEKFRGVALDVFESEPLNKDNKLWECENVIVTPHNSWV
                     SDKNKERTFNMVYNNLKHYIMENKPVDNVVDISRGY"
     gene            11305..13329
                     /gene="ligA"
                     /locus_tag="PC465_000766"
     CDS             11305..13329
                     /gene="ligA"
                     /locus_tag="PC465_000766"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HDF2648094.1"
                     /translation="MSIKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISL
                     EEEHPELKRIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVG
                     ENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTVKSIPLKINDKK
                     ELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFV
                     FNMENIEEYDLESHSESLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLDYE
                     IDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSA
                     ILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDE
                     IDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRGIIHFVSRDAMNIDGLGESI
                     ITLLLNEKIIQDVSDLYYIKKEDVVDLERMGEKSADNLINSIEKSKENDLWRLINGLG
                     IKFIGVKAAKILAYNFKDLDEVISATSEQLEELEEFGSIMANSVVEFFKEDKNMNVIN
                     KLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLPTLKRNDAKDMIEKRGGKATSSVS
                     KSTTFVLAGEEAGSKLTKASDLGIKVIDEERFLELLKLSSKDEVKAVLES"
     gene            13489..14838
                     /gene="rph"
                     /locus_tag="PC465_000767"
     CDS             13489..14838
                     /gene="rph"
                     /locus_tag="PC465_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HDF2648095.1"
                     /translation="MTRSYDRSNEQIRPVKITRDYTKYAEGSVLIEMGETKVICTASV
                     EEKVPPFLRNSGTGWINAEYSMLPRATQQRKIRDASRGKIDGRTQEIQRLIGRAIRSV
                     VDLNKLGERTIWVDCDVIQADGGTRTASITGAFVAVAEAIYKLYKAKTIKEMPITNFV
                     SAISVGIVNGIHMLDLCYEEDSKAQVDMNIIMTDKCEFVEVQGTGEEKPFSRADLNLL
                     LELGEKGNKELIRLQREALGEIADEILGMDYGNEVVIATNNAHKLEEIGEILKDFEYK
                     VYSLKDVDLAGIEIVEDGKTFEHNALIKARTIAKKTKLIAISDDSGLEVDALGKKPGV
                     YSARYAGEHATDEENRKKLLKAMQNVPMSKRNARFVSAIAVVFPDGKEFVVRGICEGM
                     IGFEEKGKNGFGYDSLFIVKGYDKTFGEIPSVIKNSISHRANALKLMKQEFIKRVVK"
     gene            14838..15308
                     /locus_tag="PC465_000768"
     CDS             14838..15308
                     /locus_tag="PC465_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2648096.1"
                     /translation="MKIGIVSDTHMMIKNMEKTIPYLKECDLIIHAGDNFTDSRYIHS
                     MTNVGIIAVKGNCDFDAVEEEVVFEVANKTIFLCHGDKYGVKYGTNMLEKKATEVDAD
                     IVIFGHTHTPFREIKDGVLYINPGSTSLPRGVSYKSFVIMNIEEDDIKIEEIRI"
     gene            15502..16788
                     /locus_tag="PC465_000769"
     CDS             15502..16788
                     /locus_tag="PC465_000769"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HDF2648097.1"
                     /translation="MKAELIKKEGNKVTLKITVDNNKFEAAVNKAYNKSRNKYNIPGF
                     RKGKAPRIVIETQYGKGIFYNDAIEILFPEVYPEAIKELDIDPIDNPDLDIEEISKDN
                     GLVMVLNVEVKPEFELGNYKGIEIAKVENTVSDENVDAKLQEMVEKNARLVSVEDKAL
                     EDGDTAIIDFEGFENGVAFDGGKGENYNLVIGSNTFIPGFEEQLVGKKAGEEVEVNVT
                     FPEEYHSQDLAGKPVVFNVKINDVKVKELSALDDEFAKDTSEFDSLDELKADVRANLE
                     EEAKNRADAETRNSVVEKVAENTEIEIPEVMIQHQIDNMLNELNYQLQYQGFGLQQLL
                     EMTGRTMEELREERKEDAKKLVKSSLVLEAITKAEGIEATEEEFKAELEKMASAYNME
                     VEKIEASLRDADKEDIKGQIKIRKTIDLLVDNATIA"
     gene            16938..17522
                     /gene="clpP"
                     /locus_tag="PC465_000770"
     CDS             16938..17522
                     /gene="clpP"
                     /locus_tag="PC465_000770"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDF2648098.1"
                     /translation="MALVPVVVEQTGRGERSYDIFSRLLKDRIIFLGDQVNDATAGLI
                     VAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICIGMAASMGAF
                     LLAAGAKGKRLALPNSEIMIHQPLGGAQGQATDIEIHAKRILKIKETLNEIFSERTGQ
                     PLEKIKMDTERDNFMSALEAKEYGLIDEVFTKRP"
     gene            17541..18791
                     /gene="clpX"
                     /locus_tag="PC465_000771"
     CDS             17541..18791
                     /gene="clpX"
                     /locus_tag="PC465_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HDF2648099.1"
                     /translation="MSKYEEKRQLKCSFCGKNQDQVRRLIAGPNVYICDECVELCDEI
                     IQEEIEDTIDEDTTSLPKPKEMMEILNDYVIGQEKAKKALSVAVYNHYKRIYSKKSSS
                     KDIEIQKSNILLLGPTGSGKTLLAQTLARTLNVPFAMADATSLTEAGYVGEDVENILL
                     KLIQAADFDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAN
                     VPPQGGRKHPHQEFLKIDTTNVLFILGGAFDGLEKIIQKRGGDKTLGFGAKIESKKEL
                     DLGKLYEKVLPEDLLKYGIIPEFIGRIPVLATLELLDEDALMQILQEPKNALVKQYKK
                     LLELDDVELEFEEGALRAIAKKAIERNTGARGLRSIVESVMMETMFEVPSRDNIKKVI
                     VTEKSVNEDSVNPIIVLKDQEESA"
     gene            complement(18862..19389)
                     /locus_tag="PC465_000772"
     CDS             complement(18862..19389)
                     /locus_tag="PC465_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF2648100.1"
                     /translation="MSEIILLFLIFLKIGAFSFGGGYAMLPFIQQEFISKYHFITNQE
                     FLDLLAISQSTPGPVAINSATFVGFKTAGFFGSLAATIGVTIFALIGLTIISKLFSKF
                     KNNKKVENLLTVLRPITLGFILSAAFSSAKEVNWDLYGIIAFIASFYLLYKGKIGSIA
                     IVFVFGILGILLTFL"
     gene            complement(19377..19889)
                     /locus_tag="PC465_000773"
     CDS             complement(19377..19889)
                     /locus_tag="PC465_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF2648101.1"
                     /translation="MLKLFLTFLKIGAFTFGGGYAMVPLIQDELVNKQKLLEQEEFID
                     YLSIAQSYPGVLAVNISVLLGYKLYGIPGVLICTLGSALPSFCIVLVLSYLYFKNSSS
                     KILDGFFKGVAPVVIALILYSFTSMFKKLPKSKTNILLLIIAVLSVGVFNISPIYLII
                     GGGVYSLCQK"
     gene            20069..22432
                     /gene="lon"
                     /locus_tag="PC465_000774"
     CDS             20069..22432
                     /gene="lon"
                     /locus_tag="PC465_000774"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HDF2648102.1"
                     /translation="MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQA
                     MMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGRVK
                     KIEQEDGYFRAVIEEIVFDSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILI
                     SLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKK
                     ITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEK
                     IEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLE
                     KVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVR
                     DEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVL
                     DPEQNKDFVDHYLEIPFDLSKILFVTTANSLGNIPRPLLDRMEVIEVSGYIEEEKLNI
                     AKKYLLPKQIKEHALKESFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKY
                     VEDPTLEEVVINKSDLETYLGKDMFKYQLAEVNPQIGLVNGLAWTEVGGVTLEVEVNV
                     LKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPEFYKTNDIHIHIPEGAVPK
                     DGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITK
                     VLIPKECEADLDEIPENVKEKMEFVLVEHMDEVLEQALLKSGENNEN"
     gene            22422..23033
                     /locus_tag="PC465_000775"
     CDS             22422..23033
                     /locus_tag="PC465_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HDF2648103.1"
                     /translation="MKIRSSEITMSAVNKSQYPAEGIPEIALAGRSNVGKSSIINTLL
                     NRRNFARTSQTPGKTRTINFYLINNEFYFVDLPGYGYAKIAKSEKEKWGGIMERYLES
                     RQELCSIFLLVDIRHEPTADDKLMYEWIKHFGYNCVVIATKADKISRGQYQKHISIIR
                     KKLQMESSEKVIPVSSLKKTGVEELWEEIVNQYNQHGYEITVD"
     gene            complement(23298..24668)
                     /locus_tag="PC465_000776"
     CDS             complement(23298..24668)
                     /locus_tag="PC465_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2648104.1"
                     /translation="MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQ
                     WVVTAYMLVVTATMLFFGKLGDKVGSNRLYTLGFFIFTIGSFLCSMSNNLSTLISSRI
                     FQAVGASILMATGLGIVSNAFPANEKGKAIGITGAVVGIGNMSGPVIGGIILEHFGWP
                     SIFIINIPIGIIAVFLGIKFLPKPVLDEQNKSFDIPGLLLFASCTTLILLAMNEKGNT
                     RLYLGITALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLL
                     PFYLEQLKNLSPMMAGYVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLV
                     GMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATIRNL
                     SFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNQSYWIAASVCFIGLILTVFFMRK
                     TDKSIS"
     regulatory      complement(24843..24958)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            25246..26325
                     /locus_tag="PC465_000777"
     CDS             25246..26325
                     /locus_tag="PC465_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2648105.1"
                     /translation="MEGKVKKAFPGGNTSQGSYSFFDYIIPENVKRVFCLKGGPGVGK
                     SSLMKKIYKEFLHRGYDIDLYHCPSDPSSLDGLVIKKLGVVLMDATAPHTMDPKLPGA
                     LDEIINLGDYWNTEELEKNKQEISVYDKDISNSFKRAFKFLKSAEPIFRDIEEKYSDC
                     MDYGKVNLVTEEFIKRLFDGVKSTGNLKREKHLFGSAITPVGCLDYTENILKDVKKVY
                     YLDGEIGTGKTTLLNKVYKKAIEKGLNVEVYHYPLIPEKIETVLLTDLDIGITISTTF
                     KEEDTIDLNQFLNREKLLKYEEDIKFDEKVLDDLICWAVLNLKRAKSKHDIIESYYSP
                     NMRFDEVGKLRDKLIKRILKYEENL"
     gene            26716..27396
                     /locus_tag="PC465_000778"
     CDS             26716..27396
                     /locus_tag="PC465_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HDF2648106.1"
                     /translation="MKKQYVFIILASTILGILVGTIFRDYNNEETVYTSKDKSIRKEI
                     KMTRKSIKELTKEKDKLDKEINSMKQNQKNSEEISEIETLRDSLSYSDVKGSGIILSI
                     DAIDEKTGNIANSIDYNKILVKVINELKVNGGKYIEINGQRINQYSEVVLAGSHININ
                     GVPVAQPYEIKCIGDKEKLSNYVDKGSKYLDSIQTNYPMKISIKTEENISMKKMNIPN
                     KLKYIKGD"
     gene            27389..28768
                     /locus_tag="PC465_000779"
     CDS             27389..28768
                     /locus_tag="PC465_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HDF2648107.1"
                     /translation="MIKIILEESSLPMLIPEKLAKKYNVFPVEFQDDNLVVEIEDEDI
                     YALQDLRLATGKEIILKKEKKELISEKIEKYYNSFELDEDYAKKLFENLLEKAIKENA
                     SDIHIEPFKEHLIVRMRVDGELKEVSKFLVDVYPSLSTVIKLKASMDITEKRLPQDGR
                     VDIKLGGNLIDIRVSSIPTVYGEKIVLRILNRDTFLKDKLELGFSEEAIKSINRIINK
                     RAGILLVTGPTGSGKTTTVYSLLNDLKGINKNIMTIENPVEYKMDGISQIQVNSKVGL
                     SFDVGLRAILRQDPDIIMVGEIRDAETAKIAVRAAITGHLVISTLHTNDAVSSIARLL
                     EMQIPPYLLNASLIGVISQKLVRKVCNHCSHEIMIKDNFSGDVNTKVAVGCEKCNDKG
                     YFGRTAIYEILEINDDIKTCIRNMEDSSTIKDVAQNNGMITFEDSCKRLINEKITTLE
                     ECLVVNEMI"
     gene            28939..30024
                     /locus_tag="PC465_000780"
     CDS             28939..30024
                     /locus_tag="PC465_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HDF2648108.1"
                     /translation="MRLSKNIFYNLEKFYLVLNRISDKEIRVICKEIGILLESGCEIT
                     KIFEIIESQSSKKVKNLLSIVSNHIQKGNSIAESFQITGIFSKFFISMIKAGETSGNL
                     DIIMSDLSNYYDKEYKLKMKIITISIYPIILIILSILSMLFIFVFVIPNFQVVFTNNG
                     IEPPLITRVLMGISIVVTNNLAYIIFSFILFSIGNIYFFITNDNIKKLINSLKFKIPF
                     IKKINQLVATTRFSRALSVLISSGIQIVEAIDMSASVVDNEFIYERLKISNNYIKKGN
                     SIGKSLNLANIFPKLFISMANTGEESGKLDKSLNVINKFYENELNNKIEQIMKFIEPM
                     LIVFMGLIIGTFILAMVVPMFDAITNF"
     gene            30078..30437
                     /locus_tag="PC465_000781"
     CDS             30078..30437
                     /locus_tag="PC465_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HDF2648109.1"
                     /translation="MINLINKKRKGFTLVEMIVVVTILGVISSIALVKYSKVQESAKL
                     NADYTNAANIVTAASMAINDDEKTIDSLSVETLKEKGYLNTVPVPQSTSGKFELVIND
                     SGTDISVNINSKQFYPK"
     gene            30490..31362
                     /locus_tag="PC465_000782"
     CDS             30490..31362
                     /locus_tag="PC465_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HDF2648110.1"
                     /translation="MAIIKKILNLEINDDYIRLVFLRKSHKKVFIDKSIIKEINFDIK
                     NDSNSIEKIKYIEDVVRFVKEEIGKSKILYKNLYFNIQIQDIVIRNVEVLNTKKKRDI
                     LSMIEFEITQYIPININNYSIKYKVINSKNDKLNIQVILFPKSIIQLIKNISENLNMN
                     PKTININFDILQKLINLNLIENFSEEGVFIECKKSQLIINITKDKKIRETYLLSKEGK
                     SYEFIKRLLRDFKYVYYYGIENCFIEEYFKYTDKSIEVNPLRLKDKVKVENNFDADLE
                     DNRINYINSIGMII"
     gene            31363..31806
                     /locus_tag="PC465_000783"
     CDS             31363..31806
                     /locus_tag="PC465_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648111.1"
                     /translation="MKVDKTINFLNGFKKTKPCNKIYKIIIVLILTCILFKSFMYVKS
                     INELEDYISQNKLVDKSKNTLPTTDKTREKFSKIKLNEIKKIYETIGINSITKISIDK
                     NKLEMEGVCSDLDVLNNLRKIKYIKYYYIDSIVRDGEYYRFRIKS"
     gene            31821..32405
                     /locus_tag="PC465_000784"
     CDS             31821..32405
                     /locus_tag="PC465_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648112.1"
                     /translation="MRLNNREKNLLKILLILVIILASDIAVSYLEENLTSLKNEKQNI
                     INKINNQDNYQIKDNKHIDDKYIESVESNKNEELKNNFNNSFLDKKTNKDIVLLVENE
                     LRDIVNVEYINQESSLDNHNKKQVNLEIKVNGELANVLKLEGVMKKLRLNNKLEKIEI
                     NKLKVNNFDVQNIPNEYKQEKDNIVECKMTVRVI"
     gene            32658..33695
                     /locus_tag="PC465_000785"
     CDS             32658..33695
                     /locus_tag="PC465_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HDF2648113.1"
                     /translation="MLGRNELCPCGSGKKYKKCCLNKDIVSERACRKTELSQKQYTDL
                     YSKLYDYSRQDKFKEECEKAKEMFYIMQNDSVNEKFERFFNTYLIQDHIMENKKVMTV
                     GFLEENGANLSQSEVSILKSMFESYVSIYEVKEVSAGKIVLKDCLSGNELCTEDVKLL
                     RSFKIGSCMIARIVDIEGTNILIDITISISNEVKDIILKDIMNLFNQYQDVYKDMKSF
                     LIYHTHILYKYIQQLLDPSIAEYLKRERDKNDTKVNSENELAEEECKVLDTLKENVEK
                     ENIDACIEFWNEYKKNHENIKGAENGWAAAVEYYVKKEAGQPITQVQISKKYDISSST
                     LGKRYKDLKIS"
     gene            33776..34141
                     /locus_tag="PC465_000786"
     CDS             33776..34141
                     /locus_tag="PC465_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648114.1"
                     /translation="MSLSLGNAIAVSTNFIKSNPAVPVYNGEEIYAVIYHIEIGYNNG
                     VSPDTKQYIIIDYKEFDLSMDKKNELINIAKEYCKSKGIVENENLEINLLDNEEAENF
                     LEKVFNNMKVIRGLITKKG"
     gene            34146..34463
                     /locus_tag="PC465_000787"
     CDS             34146..34463
                     /locus_tag="PC465_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648115.1"
                     /translation="MDYIGIENITPYENTYEFSVYEYDDEITLGSEKLYVCELRVVLI
                     KVNSLYVERLHKSVEAMVLVKNLKKDLDKTLVVNKIKNFVLDEIWVENLVKENIEVIF
                     VES"
     gene            34511..36115
                     /locus_tag="PC465_000788"
     CDS             34511..36115
                     /locus_tag="PC465_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648116.1"
                     /translation="MLRVSNVKLGIDKDISLLKDVILKKLKIKEKNLVKYSIYKESID
                     ARKKGKMEFVYSVDVEVKDENKILNSKIKDVTKIKEIRYVNVPVGDKKLKNNPLVIGS
                     GPAGLFAGLLLAQMGYEPIILERGLDVDSRTKDISDFWTTRKLKNNSNVQFGEGGAGT
                     FSDGKLTTRIKDIRCRKVLEELVQFGAPDEILYSHKPHVGTDILKNVVKNIRNEIISL
                     GGQVRFNSKVTDIVVSNDSIQSVIINDTEKIDTDTIILAVGHSARDTYEMLYSRGIKI
                     VQKPFAIGARVEHPQDLINKAQYKDFYNHPRLGAADYRLIEHVSNGRTAYTFCMCPGG
                     SVIASASNDFEIVTNGMSEHARDKINANSAFLVNVTPEDFKSDNPLAGVHFQQKYEKL
                     AFELGGKNYNAPVQLVGDFINNKTSLNLGSVEPSYRPGYTLTNLSECLPSFVTETMRE
                     AFISLDKKLNGFAMYDAVLTGVETRSSSPIRIVRDENTLESVSIKNLYPCGEGAGYAG
                     GIVTAAVDGIKCAEKIIQKYTNNTKI"
     gene            36239..37867
                     /locus_tag="PC465_000789"
     CDS             36239..37867
                     /locus_tag="PC465_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HDF2648117.1"
                     /translation="MNIIISLMGGLGLFLYGMNLMGEGLQKSAGTKLKKIIKLLTSNL
                     FMGVLVGTGVTAVIQSSSATTVMVVGFVNAGIMTLKQAIGVIMGANIGTTVTAQLVSF
                     DLTGMAPVALGVGIILYLFGNKPRIKNIAEILIGFGILFTGMDFMKMAVEPLRDYQGF
                     TDLLVTFGRYPLLGLLLGFGITAIIQSSSASMGMLVALAAEGLVPLSAALPILYGQNI
                     GTCVTSLLSSIGANKNARRAAMMHLIFNVLGTVIFLIFLNKPVVSMVTSWDPSNVARQ
                     IANTHTLFNIISVLILLPFTNLIIKLAIKLVPDRAGDIDEDETKTIKYIDDRMIETPS
                     IALANTIKEALRMGEKAKESLNASMEALVEHSTEKIDKTYRRERLINDLQKAILNYLL
                     KLSKAPLDDDSREVVDTLFNTVNDIERIGDHAKNIAELSQVAIDSNISFSEEGQSELD
                     VMYNRVVSAYTYALESMRTDNVDLACKVIKIEEQVDIMEKSCRANHMYRLNNNLCSIE
                     NGVIYLDVISNLERISDHAVNIAQQVIAKRLGND"
     gene            38132..39481
                     /locus_tag="PC465_000790"
     CDS             38132..39481
                     /locus_tag="PC465_000790"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HDF2648118.1"
                     /translation="MGKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTF
                     LGWIDLPKNYDKEEFDRIKKSADKIKSDSDVLLVIGIGGSYLGSRAAIDMVSHSFRNG
                     LKKEQRKAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKD
                     YLEKKYGKEEARKRIYATTDASKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLP
                     IAAAGLDIDAMMKGANDAREAFQNPDLKSNDSYRYAVARTILHRKGKDVELLVNYEPQ
                     LHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENC
                     KRNITISSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYN
                     FGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK"
     gene            39637..40716
                     /locus_tag="PC465_000791"
     CDS             39637..40716
                     /locus_tag="PC465_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDF2648119.1"
                     /translation="MSRRKKGISLVILVAIISSILSSFLTIILVKDNLVSKSTGSSTP
                     IVVNDDGKSQNIYQAVAEKATPSVVGITTTSVDTSNMFAIPTETQGVGTGIIVDSNGY
                     ILTNSHVISDGQATSVNVLFNDGSTTSGKVVWFDQQLDLAIVKVDKTGLTPAEFADSD
                     KVKVGDISIAIGNPLGLDFQKTVTQGIISGLDRTIQTEKTNMTGLLQTDASINAGNSG
                     GPLLNQKGQVIGINTAKASQAEGLGFAIPINTAKSIVEEVIKNGKYEKVTLGIKGTDV
                     SNYEAATGTKLSTDKGVYVAEVISGSSAEKAGVKVGDIITKVGDTDITGMNDLNKKLY
                     TFSKGASTKITVNRGGKAVTINVNF"
     gene            41061..41969
                     /locus_tag="PC465_000792"
     CDS             41061..41969
                     /locus_tag="PC465_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HDF2648120.1"
                     /translation="MNPLVINLQKCSIHDGPGIRSTVFFKGCPLECVWCHNPESQTYT
                     KQVLYNEERCSKCEACINICPHKAIYKGETKICLDQDKCEFCETCLDYCVNNAREIVG
                     QEYSVRDLVKEIEKDRIFYEESGGGVTLSGGEVMAQDMDFICGVINMCKSKGIHVAID
                     TCGYAKSENYERVAKCADLFLYDIKLIDEDKHIKFTGKSNDLILKNVKILSELGANIN
                     IRIPLIVGVNVDDENLEVKKMIEFLKPLNIQAVSLLPYHNIGKHKYDKIYKKYEGEEL
                     QRPSEEKLEEIKRLFEASNFNTKIGG"
     gene            41974..44343
                     /locus_tag="PC465_000793"
     CDS             41974..44343
                     /locus_tag="PC465_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HDF2648121.1"
                     /translation="MSRGTFERTKKLREESINAEPHISIERAVLMTEAYKKYEGSVEI
                     PVLRALSFKHYIENRTLSINDGELIVGEKGDSPNGAPTYPEICCHTMEDLEVMHNRDI
                     INFSVSEEARKIHKEEIIPFWKKRQTRDKIINAMTPEWLAAYEAGMFTEFMEQRAPGH
                     TVCGDTIYKKGFLDLKKDIEARLKELDFLNDLDAYNKKADLEAMAIACDAMVILGKRY
                     AEKARQMAEEETDEAKKKDLLLIAETCDVVPAHKPETYHQAIQMYWFVHIGVTTELNI
                     WDAFTPGRLDQHLNPFYERDVENGILDRDRAQELLECLWVKFNNQPAPPKVGITLKES
                     STYTDFANINTGGINPDGQDGVNEVSYIILDVMDEMKLIQPSSNVQISKKTPQKFLKR
                     ACEISRKGWGQPAFYNTEAIVQELMEAGKTIEDARLGGTSGCVETGCFGKEAYVLTGY
                     MNIPKILELTLNNGYDPISKKQIGIETGDPRNFQSYEELFEAFKKQLHYMIDIKIEGN
                     AVIENICAKHMPCPLMSTIVDDCIEKGKDYQRGGARYNTRYIQGVGIGTITDSLTAIK
                     YNVFDKKKFDMDTLLKALDANFEGYEAILNLVSNKTPKYGNDDDYADEIMQEIFNAYY
                     NEVTGRPTVCGGEYRVDMLPTTCHIYFGEIMGASPNGRLCAKPVSEGISPEKGGDTNG
                     PTAVIKSCAKMDHIKTGGTLLNQRFAPSVVQGEKGLDNMANLVRAYFNMDGHHIQFNV
                     FDKNVLLEAQKNPQDYKDLIVRVAGYSDHFNNLSRTLQDEIIGRTEQTF"
     gene            44668..45471
                     /gene="proC"
                     /locus_tag="PC465_000794"
     CDS             44668..45471
                     /gene="proC"
                     /locus_tag="PC465_000794"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDF2648122.1"
                     /translation="MKTLGFIGSGNMGSAMIGGIVQSGLVKAEDITVSDLSQVALDKV
                     KEEFGVNTTTDSKVAVTNSDVVIVALKPNICEKALTPLKELIDANKIIVSIAAGKTIE
                     SLESFIGSDKKIVRVMPNTPALVGEGMSALCKNSNVTDEELNMIKALFESFGEAEIVS
                     EYLMDTVTGISGSSPAYVFMFIEAMADAAVLAGMPRQQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPAGTTIEAVKVLEEEGFRAAVIKSIVACIDKSKDMSK"
     gene            46069..48825
                     /locus_tag="PC465_000795"
     CDS             46069..48825
                     /locus_tag="PC465_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2648123.1"
                     /translation="MRDEILSFVNECVLFNNFDELKKESGIITEDIVKKFNLSRTQSS
                     RLLNDLVKSDNLIKINSRPVIFLPKNKINDVVGPTKKSIYENLDELKNECKLLKQETV
                     FNSIIGYENSLKEVIEQIKTAVLYPNGGLTIMLTGESGVGKTFLAKIIYKYSVSSNVL
                     EKNSPYNVLNCAQYYNNLELLSSLLFGHVKGAYTGANESRAGLIEQSDGGVLFLDEVH
                     RLNSEGQEKLFTFMDTGTFSRIGENGVIRKARVRLIFATTESLSEFLQTFLRRIPINI
                     YVPNIEERGTIEKRKIVEHFIYEESKVLGLPIEITQITLNAILKIKFKGNIGECKNVI
                     KYACGRAYAKNQRRNGNIFVTLQDLPRNLYIENVDIFQFQSGKSKSIIFSPKQFSIEM
                     SNGRNKRNIIYQSFIKCLDYFDRLEKNEITKEKFSKKSSNLMIRLMDNLVFSNNDENN
                     NVLMELIISIMQDIFRNLEVNNNIKYDGNNVLAFSSYLYLKDESYQLSDEYKALENKL
                     LIYLKKESYKEYSIISKISTLITNRLDMYLNNVDTIIMIIFIKSTIIRMKFNQVNATI
                     IAHGYATASSMANVCNRMLGKNIFTAIDMPIDATIADVSKQMSRYLEGDRIKNGLIVL
                     FDMGSLNLIYEDLKNKINSPMLFIDQISTISALEVGNLLMQGKNIEEIAEIMDEETKP
                     NIQLYYPQKNKEYAIISSCFTGIGTAIKIQHLLSESLIGIVDVKIIPYDYDSLVSMGD
                     KEPVFEMYDVMAIVGTANPNVNGVDFILLEDIISGKGEDDVFRIFSRVVENEKIKNIN
                     DSIVKNFSLIRVIDSLTILDSKKIIERIEEGINAIENIQKKKLSNDKKISLYVHLSCM
                     IERLVRQTEIEEYTDMDLLIKNHHSEVKLIKNAFSVLEKSYSVQIPISEIGYIYNIIY
                     GLPQ"
     gene            48957..49436
                     /locus_tag="PC465_000796"
     CDS             48957..49436
                     /locus_tag="PC465_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2648124.1"
                     /translation="MVSLMRIDDRLIHGQVAYGWATSLGINVILVANDEAKNDQMKAM
                     SLNLAKPSNVTLYIRGVEESGEIVEKFASSKKSNVLVLVKNTKDALVVAKNSGGVLKE
                     INVGGLRYEEGKKKLTDLVAVDDDDINNFKQIGDLGIDIEFRMLPRDKKKQLSDLIK"
     gene            49452..49874
                     /locus_tag="PC465_000797"
     CDS             49452..49874
                     /locus_tag="PC465_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HDF2648125.1"
                     /translation="MKKFLIATHGELSRELVDTSKLIIGSLTNIEYFCMTTDKSADDA
                     EKEIRSILSNNKDSEEFVVLTDVFGGSVANICTNLLLQGFKFELLTGVNLPMLLSILL
                     LVEEDTKLIVKSGLEEAKNGIVYVNELLENQNKIKNVM"
     gene            49914..50705
                     /locus_tag="PC465_000798"
     CDS             49914..50705
                     /locus_tag="PC465_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2648126.1"
                     /translation="MLVQATMLAIIAGVGILDGRIFGQSMLDRPIVTGMLVGLVLGDI
                     KSGIMIGAQLELIWMGIAGIGAATPPDVVTGGVLGTAFAILSGNGAEVALAVAVPVAV
                     LAQSLGVLVRIINSYFSQKAVFYAKQADFKKVTIMMWLPVILFFLSTSVPTFLAIMIG
                     ADKVTALINAIPKVILDGLGVAGTLLPAVGFALLMDMLLSKKMSVFFFIGFLLASYGG
                     LDITAIALFGVCVAFVLNFYINNKENNQNPQLAINTLTEGEIDFE"
     gene            50698..51498
                     /locus_tag="PC465_000799"
     CDS             50698..51498
                     /locus_tag="PC465_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2648127.1"
                     /translation="MNKLTKKELRSMFWRSFALQGAFNYERMQNLGYCYSMLPAIKKL
                     YNKKENQAKAIERHLEIFNTTTVVVPAILGITAAMEEENANNPEFDESSISAVKTALM
                     GPLAGIGDSLFWGTFRIIAAGVGVSLAKEGNIFGPLLFLLLYNIPAFALRIFGLKYGY
                     QVGVNSLERIQREGLMEKIMSMATTVGLFVVGGMVATMLSITTPLKFNLNGAEVILQD
                     ILDKIIPNMLPLTFAFVIYYMLKRKVSVTKLTIGTIVTGIALHAIGLL"
     gene            51546..52601
                     /locus_tag="PC465_000800"
     CDS             51546..52601
                     /locus_tag="PC465_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2648128.1"
                     /translation="MTIQDYMLETPVRMREIISNADSLFNEVKRTNLKKIIITGSGTS
                     YHSGVQVQPYLQNLLDIDVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMK
                     LAEDKGCKIASMAGCKNALIDEISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQI
                     AREKGIISSEKYNEEINKILDAINRFEAVYKLSKQWIERNKEKLVNSKEIRIIGHSDI
                     YGDTLEAALKLLETMRIPVTGYEFEEFIHGIYNAINSDSTIFILDTGKEPRVTKMIDV
                     LSGWTENVFAIGRDVTENDKNLKIDITDNPYYQTFNFIVPIQLICGEIPTLRGVDPSV
                     PKDTRFHMKLGSKKLNK"
     gene            complement(52780..54726)
                     /gene="feoB"
                     /locus_tag="PC465_000801"
     CDS             complement(52780..54726)
                     /gene="feoB"
                     /locus_tag="PC465_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDF2648129.1"
                     /translation="MINVALLGNPNVGKTTVFNLLTGSNQYVGNWPGVTIEKKEGFLG
                     KEIKVVDLPGIYAMDTFSNEEKVSKSYLENEDVDVIVNVVDASNLSRNLYLTTQLMQF
                     NKPIVILLNMLDIAESKGVNIDAKKLSEELGVIVVPIIAKKKNGVDRIEEEIKGATQK
                     AFIYQKNFGSETETYKKLESILSRCTKTTYTQKKSISDKIDNIVLNPILAYPIFIGVL
                     FLLFKFTFDWVGGPLQEGFASLIEAYISAPVSDMLSNSSPWFKSLIVDGIIGGVGGTL
                     PFFPLIFTLFFGISLFEDSGYMSRTAFLMDKVMRKVGLSGKAFIPIVMGMGCSSPAIM
                     ATRTLESEKDRRVTALIAPLMTCGAKLPIYALFVAIFFPHNAALVTTSLYLVGIVMAI
                     VVALFLNKTAFKTEAEPFILELPEYRIPTIDALIKNTWNKSKGFLIRVVTVMFAMSVV
                     IWGLSSFNVFGYTEDINVSFLATLGHIISPIFKPLGFDDWRTSVAILSGLGAKEIVVN
                     SLNILYGNLTVVLPTIFNGVTAYTFLIFTALYTPCIAALATMKKEYGNKMMFTSFAYQ
                     FILAWIMAFIVKSIGGVLFMGNSIIEALIGGIIIVLALFILFNKFKSTKNGNVCSGCS
                     ICSGCPSANSCSSKEDSNKKNNAH"
     gene            complement(54744..54962)
                     /locus_tag="PC465_000802"
     CDS             complement(54744..54962)
                     /locus_tag="PC465_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2648130.1"
                     /translation="MTVYDLKIGEKGFINSIDGDIKLSKRLLALGCINSTEIEVKKVA
                     PLGDPIIIRFRGFDLAIRKSDAKNISLQ"
     gene            55168..55677
                     /locus_tag="PC465_000803"
     CDS             55168..55677
                     /locus_tag="PC465_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HDF2648131.1"
                     /translation="MKTRKMTFLGLMIGYSLALYVLETYIPNPLIVIFPGAKLGLSNI
                     ITLISLMLLGVKDTVIIVTIRVILSSIFAGPLSYLLFSIGGAYLSLLFMYLASKIKDL
                     SLIGISIIGAIGHNIGQLIVASLIIENILAIGYLPFMLMASLVTGMFVGLVSRYTIPK
                     LKHFYSKFY"
     gene            55755..55916
                     /locus_tag="PC465_000804"
     CDS             55755..55916
                     /locus_tag="PC465_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="HDF2648132.1"
                     /translation="MANNELEALKNEIEAVREEINTYIEYPEIFQEELVESSKKIDIL
                     INKYMYLSK"
     gene            56067..56732
                     /locus_tag="PC465_000805"
     CDS             56067..56732
                     /locus_tag="PC465_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDF2648133.1"
                     /translation="MIDIGSKEIAIRLLLALIIGGIIGLEREKIRQFAGFRTHILIAI
                     GSCIVSITSIQLFFDYNLYTNADPARMPAQVLSGIGFLGAGAILKNKGGVKGLTTAAG
                     MWATACIGIAVGYGYYELAILGGLFVMIALFVLRIINTFLFSQEKNVLILKLSNLDSI
                     PFLYDKFEKNQLIVRNMEIECRNEEYWKVNFFVSYAKRIHLHDVMKEINMIEGVINVD
                     YLD"
     gene            56798..58582
                     /gene="pepF"
                     /locus_tag="PC465_000806"
     CDS             56798..58582
                     /gene="pepF"
                     /locus_tag="PC465_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HDF2648134.1"
                     /translation="MGTDRSTIEEKYKWKIDKMYSSKEEIEKDISKVKNLIQEVKEYK
                     GKLSESKENLYKVLNISENASRIVQNLYVYTHMKQHEDTRINDNQGRATKTEMLSTDL
                     GVATSYIVPEILAIEENKLSEYLKDEKLSFYAKYIKDILRDKPHTLSEREEEILAATS
                     ELSTIPENVYDMLAYADMEFPEIEDEEGNKVKLSHSNYSLFIKSKNSRVRKDAFEGEF
                     STYEKYKNTFASTLYGGIKSEIFYAKTRKYNSAIEASLFSDDVSLDVYNNLISAIDKS
                     IPNLNKYVELKKKFLGLNEIHMYDLYVPLTDKFDMDIPYDKAQDIILEALKPLGEEYL
                     KIIKSAFDEGWIDVYDNEGKKGGAYSWGSYDSHPYILMSYKNDLNSLFTLIHELGHSV
                     HSHYSRTSQPFLYSDYKIFVAEVASTLNELLLINYLLENSKSKDETIYLLNYYLEQFR
                     TTVHRQTMFAEFEKIVHQRVESGEPLTADEFTNIYYKLNEKYYGKSAIVDKQIGIEWA
                     RIPHFYSNFYVYKYATGFSAASALSQQILSEGSTAVDRYINFLKSGGSEYPLEQLKSA
                     GVDMTKKESIEEALNVFAELVNKLEKEL"
     gene            58834..59667
                     /locus_tag="PC465_000807"
     CDS             58834..59667
                     /locus_tag="PC465_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2648135.1"
                     /translation="MFKKKIGVLLASTMLVGALAVGCGSNSGDSGDSSKVSVSGSTSI
                     GPLMETIGEKFQEKNQGVSVEVQQIGSSGGIKNAIEGTSEIGMSSRDLKDEEKSAGLK
                     ETKIAIDGIALITNTANSVKNLTMDQVKGIYTGKITNWKEVGGNDAPIVIVSREEGSG
                     TRDGFQEIVGFDSEELTKDAQISDGSGNIKTTVEGNENAIGYISFGYVDEKVNSLKIN
                     DVEATDANVIANKYPISRPFILVNKEDGLSEKGKALIDYILSDEGQALVSEKGFIKVN
                     Q"
     regulatory      59900..59983
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            60563..61239
                     /locus_tag="PC465_000808"
                     /pseudo
     CDS             60563..61239
                     /locus_tag="PC465_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            61311..63326
                     /locus_tag="PC465_000809"
     CDS             61311..63326
                     /locus_tag="PC465_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF2648136.1"
                     /translation="MKKYNILKGTLIVLIVSLLAITGLNLLYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGKLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGT
                     QSPYGNATYRMRIKNEGKDKLLSLELPEIFSASEVWINGEMVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKNTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKIYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDLSY
                     FMVVLCIICINGSISKIEENKVYRFLILPLGITMSIISIVIPIILFPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFVIVILFSVMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KRFLADVAHDLKAPVSAIQAFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNNFIKEIYENNLPDTQACGVNFEAYVLEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKISDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLCFL"
     gene            63376..64056
                     /locus_tag="PC465_000810"
     CDS             63376..64056
                     /locus_tag="PC465_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2648137.1"
                     /translation="MQTKILIIDGDKDNCQKLKGFLEEKGISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILSDGDGWTLCKKIRNVTTCPIVYMTYINEDQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
     gene            64573..65019
                     /locus_tag="PC465_000811"
     CDS             64573..65019
                     /locus_tag="PC465_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648138.1"
                     /translation="MAISDLAFGTECLKTSFQMLFSVISLVNINLLQAQILIAIGGLI
                     SILAMVSLTLFLSAKCKDSLTSMLIAFSICLIPMGIGVSWIGYLLPPGGIGFKISLLY
                     QMTSFNFLHLGGMSFWTPHIILFFSVIEIPIFIFLAIRTYCKHQVS"
     gene            65400..66317
                     /gene="pstC"
                     /locus_tag="PC465_000812"
     CDS             65400..66317
                     /gene="pstC"
                     /locus_tag="PC465_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HDF2648139.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQSIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            66319..67143
                     /gene="pstA"
                     /locus_tag="PC465_000813"
     CDS             66319..67143
                     /gene="pstA"
                     /locus_tag="PC465_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HDF2648140.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVVIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVTGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            67162..67926
                     /gene="pstB"
                     /locus_tag="PC465_000814"
     CDS             67162..67926
                     /gene="pstB"
                     /locus_tag="PC465_000814"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HDF2648141.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            67954..68607
                     /gene="phoU"
                     /locus_tag="PC465_000815"
     CDS             67954..68607
                     /gene="phoU"
                     /locus_tag="PC465_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HDF2648142.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            68765..69634
                     /locus_tag="PC465_000816"
     CDS             68765..69634
                     /locus_tag="PC465_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDF2648143.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGDYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKILRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            69721..71157
                     /locus_tag="PC465_000817"
     CDS             69721..71157
                     /locus_tag="PC465_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase"
                     /protein_id="HDF2648144.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     DLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTEDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENKYKK"
     gene            71205..72032
                     /locus_tag="PC465_000818"
     CDS             71205..72032
                     /locus_tag="PC465_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2648145.1"
                     /translation="MKIKDNKAVFHVFIRIFIIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENITPKNFWQENL"
     misc_binding    72333..72595
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            72671..75337
                     /locus_tag="PC465_000819"
     CDS             72671..75337
                     /locus_tag="PC465_000819"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HDF2648146.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKEHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKAKKEKFEEMIKSVEERLTNLESKIK"
     gene            75762..76472
                     /gene="rgaR"
                     /locus_tag="PC465_000820"
     CDS             75762..76472
                     /gene="rgaR"
                     /locus_tag="PC465_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgaR"
                     /protein_id="HDF2648147.1"
                     /translation="MFRVVICDDEKIQRSILKEFTEKLLSERCLNYQILEFSCGEDLI
                     SKYPEKIDIIFLDIQMKDINGIEVAKKIRKFDEKVEIIFTTAFSEYAPQGYEVRAYRY
                     LVKPIEYSNFAMGVNLCIDNLQRKKERYIVLNSKKGFNRILIDSILYVETVKRDLVVH
                     TIGRDYKANMSMKQAEKLLCENGFFRCHTSFIVNLRRIEDLRDNMITINEQFIPISKY
                     RLKDLKVALTSLLCDIMY"
     gene            77518..78549
                     /locus_tag="PC465_000821"
     CDS             77518..78549
                     /locus_tag="PC465_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HDF2648148.1"
                     /translation="MENICDMNNKVKVAVLDTGIDKEHDYLKDNLVGGIAFECMHDYI
                     FISDKFDDEDGHGTACASIIKKEYEDVELFVIKILRKDGITNIKVLEEALRYLLDTNI
                     RLINLSLSVIGVESVKGLFEVCYELFRKGKIIVCSLANDFDLSYPAMFNNVIGVRGFT
                     LDGDDSFWYNKKYDVQCVMDSNSYISCDINNSYRLPPKCNSYLSAKLTGKIAKILSEK
                     PGITISDLNDKLESLATRNHWDSCDFDECSRIVNFKLDLYDKENALLMKVADVVRDCL
                     DIEDNNEKLFKGSLFNKEIGLVYDNCFNLLKKLEHRFDIKFNYMDISKYDLVSIYTLT
                     ELVERYKNL"
     gene            78682..79980
                     /locus_tag="PC465_000822"
     CDS             78682..79980
                     /locus_tag="PC465_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HDF2648149.1"
                     /translation="MKYEEALEYISQTNKFGIRLGLENIGKLLELLGNPQETLNIIHV
                     AGTNGKGSVCSFVSNILRECGYKVGLYTSPYLETFTERIRVNGQNIPQDDVARIIELI
                     KEKIEIMVKEGYAYPTEFEVVTAMAFYYYSEQKVDFVALEVGLGGRYDATNIITKSLV
                     SVIVSISLDHTGILGDTIEKIAYEKAGIIKENGVVLVYDQTDEAKDVIKSVCKEKKAK
                     YIEVDFDDINIKKSDINSQIYDCTVMKETYRDLEIKLIGEHQINNSILAISVIKYLKD
                     INKLANINEESIRKGLINTKWPGRIEKIKENPIFIIDGAHNEDGAKSLAKALDKNFKG
                     RKLTLLIGMLEDKDIDSVLEILLSHFNKVITTTPNNPRAINSDILREKVLKYVDDVTS
                     KHEIEDAVNYTLETSSEDDIIISAGSLYMIGTVRTLVKKL"
     gene            complement(80094..80339)
                     /locus_tag="PC465_000823"
     CDS             complement(80094..80339)
                     /locus_tag="PC465_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HDF2648150.1"
                     /translation="MKVTFNPSGVCCREMIFEVDENNVIVDAEFIGGCNGNLSGLRSL
                     IIGQNALEVADKLNGIDCGGKGTSCPDQLSKAIRQSI"
     gene            80487..81353
                     /locus_tag="PC465_000824"
     CDS             80487..81353
                     /locus_tag="PC465_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HDF2648151.1"
                     /translation="MKIYISNYLSKSISIVDYSTLELEKEIVLEDNIYPHHFCIEKEK
                     NLIYIPSSSNGILYVLDLSNDKIIDTVSIGGSLSQVVLSDNELFVANEDSNSIYVLDK
                     NTLNPIGIIGVDNMPHGFDFDRESKKLYVPCINSIVCIDTINKNIQKKINMDFRAWHI
                     ELDKQKKEMYISTLDGKLIIIDEVSMDIKKVLYEFLLPVEIRFNYSGKKVYVADLGYN
                     NVRILDYTTSRYIGNIEINGIPQGLEISKDEKLLFVSDTQENSVKVYETANNKLIKEI
                     KVGKEPTTIICL"
     gene            complement(81357..81893)
                     /locus_tag="PC465_000825"
     CDS             complement(81357..81893)
                     /locus_tag="PC465_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HDF2648152.1"
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNY
                     FSLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDS
                     NKENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKN
                     NASYMYAEVIDLLIRDIH"
     gene            complement(82084..82287)
                     /locus_tag="PC465_000826"
     CDS             complement(82084..82287)
                     /locus_tag="PC465_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HDF2648153.1"
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTARE
                     NGYVGGYMTKKLVEMAERQMAGK"
     gene            82578..83342
                     /locus_tag="PC465_000827"
     CDS             82578..83342
                     /locus_tag="PC465_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2648154.1"
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKSDNSKM
                     PIYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAI
                     DEKGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKRTNLFRPPFGDVNNKA
                     MDICSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESQPGSIVLFHANINDVDNYLDT
                     IISRLKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     gene            83731..85044
                     /gene="prdC"
                     /locus_tag="PC465_000828"
     CDS             83731..85044
                     /gene="prdC"
                     /locus_tag="PC465_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="HDF2648155.1"
                     /translation="MNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIY
                     ASVSGKISEINDQAIVIEADEVQEDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKL
                     NIDLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKH
                     PKAIEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVIN
                     VETLTRIVEAVEQKRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKG
                     EYGEIILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRD
                     IATKMGVTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCT
                     DCSNTVMGSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
     regulatory      85448..85533
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            86115..88262
                     /locus_tag="PC465_000829"
     CDS             86115..88262
                     /locus_tag="PC465_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HDF2648156.1"
                     /translation="MKTKIKKSSIISLVIAFSMVFTAFTPIVSYADEVTSNDTILNGE
                     EQSNGQTPDVEKPSDGQVPDGEKPSDSQVPDGEKPSDGQVPDGEKPSDGQIPDGEKPS
                     DGQIPDGEKPSDGQIPDGEKPSDSQTPDVEKPSDGQMPDVEKPLDEQTPEEEKPLEEK
                     IVIEEMSLKQDIDKILDMTLSQINKIVYNFWEDEEDVKADEQSEINQVFTSKDSFISL
                     WYDKKAKVKNSCLLKEIDGSDRPYHDLRFDDITKTLTFDYVIKGLVGASSKDDKYVIE
                     GEDGEQTAFCYNNHLRPPSSNGKSPYLPAEDFNGQENQNEEAVKSILYAGSEFDGFGY
                     KQQFNLGGEENELMTYSATQSAIWIILGQMDEQERLKQYQGSINLCDKLIERAKTEEE
                     RAEYQKRKEVAINTKAYLEALLKAGREELKPNDTGKPSLSNGLTKINFEKNEDGTYET
                     EAVALVGYSGVVKLKLPDGVTAYDVDGNIIGTGEVEISTQQKFKLKSVGKPDAKANIS
                     AVSYDYIFPKAIQYYKAVLDLGQKDHSSSLPSSKQNLLSYTIEKKNGQEVNFNIGLPT
                     DDDVVNPPVPPIDDDVVNPPVPPTDDTNGHKPKPSPPIDDTVINPPVPPMDDTIINPP
                     VPPTEDAVLNPPVPPMEDAVLNPPVPPTDDTVLNPPVPSVSDTVEKTPELSRDDTIIK
                     SPKTGDETQLMSYVFISVIAICGLAYQCKIKRN"
BASE COUNT        35724 a         9453 c        15708 g        27636 t
ORIGIN      
        1 tgttaaataa atttttatat ttaagtaaat acgtgtaaaa tgaatataaa gtttttgaaa
       61 tataaagttt ttgtatctaa aatattttat ttgtaaaata gtaattaatt attgtaagct
      121 ataatatgag agtattatgg ttaatgtgaa ttttaaagat attattaaat atataaatta
      181 gaatgctatt agatggataa atggaggagt tattatgtct aagatattag tagtagatga
      241 tgagttagat atgttaaagt tgattgaaaa tgtgttgaaa agagatggac atgaagtaaa
      301 ggtaattagt gatgtagaaa aggctatgaa catggatttt aattatttta atctaataat
      361 attagatgtt atgatgccta agatggatgg ttttgaagta tgtaaaacta taagaaataa
      421 ggttgattgt ccaatactgt ttttgacagc aaaaaatatg gaaagtgata ttatgtacgg
      481 tcttggtata ggtgcagatg actatataac caaacctttt ggtgtaggag aattaagggc
      541 taggataact gctcatttaa ggcgagaaag tagagaaaaa aagaatttat taactatctc
      601 aaatgttcaa tttaactttt taggcaaaga agtttcaatt gatggtaaaa aaattaattt
      661 tactaaaagt gaatatctaa tatgtgaatt tctagcaaaa aataagggac aagtattttc
      721 aaaagaaaga atatatgagt cggtatatgg ttttgatgga gaaagtgata taagtactat
      781 cacagagcat ataaaaaata tacgaagcaa attaaaacaa tatgatattt atacaataga
      841 aactgtatgg gggatagggt ataaatgggt gtaataagta taagtgttgt ttagtgaaaa
      901 tattatatat atctacaaaa tgtttgtaaa atattaatct atatattaaa atttaattta
      961 tagattaata ttttttgtaa atgacaaaat tgtaaggtat tttgttataa aatattaaga
     1021 ttcatagtgt atactaataa tatagtattt agtataaatc ttgagcaaag gatggttatt
     1081 tctaatggat agactaaaga atattagaaa gagtttacta cagtatacat ttttattttt
     1141 gttaataggt ataacaattt acctagtgtt taaaacattg gatattaaaa tgctatcaaa
     1201 tgttatggtt atggtagata agaagttttt attcataggt gctttggcaa taatgtgtca
     1261 cataatgctt gaaggagtag taatgaagat aattatagaa agcactcaca aagttaatat
     1321 tagatttatt ggttttaagc tagccattat gggattttat tataatttaa taactccttt
     1381 tgcttcagga agccaaccag tacagatata tgtacttaaa aaatgtaaaa tgccacttag
     1441 taaggcaagt gcagttgtta ccaataagtc tattatcttc caaatagtag ttacttttta
     1501 ttgtacaata cttgttttaa tgaattttgc tatgttagaa aaacaaatga aaatgattat
     1561 gcctctagtg tttctaggga tagccattaa ttcatttgtc ttaattatga taatattagt
     1621 tattttaaat cctaaaaaaa taaaatattt tatgagaatt actataaagc atttatcaaa
     1681 aattaagttt ttaaaatttt tagataataa gatcgaatcc atagaaagtt ttatagatga
     1741 ttatagtaaa gcaataaatt tttttgcaaa gaataaaaag gtattaattt caactataat
     1801 agtaactttt attcaattaa gtgcttactt tagtgtttca ttttggatat ataaagcatt
     1861 taatttacaa ggttatagct atatttatat actgacatta caagcatttt tatatatggc
     1921 aatatctcca ataccaacac ctgggaatgt aggagctaat gaattagcct ttttcactat
     1981 attcaaatca gtattccctc aacctttgat gggatatgca gtatttttat atggtggatt
     2041 tatgtactat ttgattctga ttggaagtgg aatatttact gtaattactc actatagaat
     2101 gaaaaataga attggcagaa atattgtttt aagtgaaaac taaataagtt taaagaatat
     2161 atattgagta tattaaaaaa tatgtcataa gaactagaat attttaatta aatggttgaa
     2221 atataaagat tattatgaca tatttttttt gaaatttaag aggaattgtg agaaaattgt
     2281 tgaatttaat agatagtatt gcaaaatatt tatgattttg catattataa aaacactcat
     2341 tatctttaag ataaatttta cttatcaggg gataaatcta aggggggaat tgtatggaga
     2401 aaaaaatttt aacagtttgt ccatactgtg gagctggatg ccaattatat ctagtagtaa
     2461 aagataataa gatattaaga gctgaaccgg ctaatggtag aacaaatcaa gaaagtttgt
     2521 gtttaaaagg tcgttatgga tgggattttc taaatgaccc taaaattcta acacctaggc
     2581 taaaaaagcc aatgataaga aaacaaggtg tactagaaga ggttgaatgg gatgaggcta
     2641 taaactatac agcttcaaga ctaaatgaaa ttaaagaaaa atatggacct gattctatta
     2701 tgggaacagg ttctgcaaga ggacctggta atgaagcaaa ctatataatg caaaaattta
     2761 tgagagctac aataggaact aataatgttg accattgtgc tcgtgtctga catgcaccat
     2821 ctgtagccgg tctggcttac tcattaggta gtggtgcaat gtctaattct ataccagaga
     2881 tagaaaatgc agatgtttta tttatatttg gatataatgg agcagattca catccaatag
     2941 tggcaaatag aatagtaaaa gctaaaaaaa atggtgctaa attaattgtt actgacccta
     3001 gagtaactga atctgcaaga attgctgata tacatctacc tataaaaggt ggaacaaaca
     3061 tggttttagt aaatgctttt ggaaatgtat taatagaaga aggtctttac aataaagaat
     3121 ttgttcaaaa tcatacacaa ggatttgatg agtataaaga aattgttaaa ccatatacag
     3181 ctaaatatgc tgaaaagatt acaggaatcc cagaagagct tataagaaaa gctatgagag
     3241 aatatgcaaa aggtaaaaaa gctatgatac tttatggaat gggtgtctgt caatttggtc
     3301 aagctgttga tgtagttaag ggacttgcat caattgctct acttacaggt aattttggta
     3361 gagaaagcgt tggaatagga cctgtacgtg gacaaaataa tgttcaagga gcttgtgata
     3421 tgggagctct tcctaatgta tatcctggct atcaaaatgt aactgatgat aagataagag
     3481 aaaagtttga aaaagcttgg ggggtaaaat tatctcctaa taatggttat agtttaactc
     3541 aagttccaga cttagtacta aaagagaaaa agcttaaagc ttattatata tttggagaag
     3601 acccagtgca aagtgaccca gatgcatcag aagttagaga agcattagat gaattggaat
     3661 ttgtcattgt tcaagatata tttatgaata agacagcact tcatgctgat gttatacttc
     3721 cagctacttc ttggggagaa catgagggag tatatacatg tgcagataga ggattccaat
     3781 tgatgagaaa agctatagag ccacaaggag atgtaaaacc agactggcaa attataagcg
     3841 aaatttctac agcaatggga tatcctatga actataaaaa tactaaggaa atatgggacg
     3901 aacttagaca attatgtcca agtttcttag gtgctactta tgaaaagata gaaactcaag
     3961 gatgcgttca atggccttgt aagagtgaaa gtatggaaga taaaggaact atgtatctgt
     4021 atgaaggtca aaagttttct actcctaatg gtaaaggtaa tttgttcgct gctgaatgga
     4081 gaccccctat ggaagttgaa gatgatgaat acccatttag tttatgtact gtaagagaag
     4141 ttggacacta ttcagtaaga acaatgactg gtaattgtag aacacttagt tcattagaag
     4201 atgaaccagg acgtgttcaa ataaattcta atgatgctga aaaattagga attgaagatg
     4261 atgaattagt tagaattagt tcaagaagag gaagtgtaat aacaagagca acagttactg
     4321 atagagttaa ggaaggtgca acatatatga cttatcagtg gtgggttgga gcttgcaatg
     4381 aacttacaat agcaaattta gaccctatat ctaaaacacc agagtataaa tattgtgctg
     4441 ttaaacttga aaaacttgaa gaccaagaat tagcagaaaa atgtgtaaga gaagagtatc
     4501 aaagtttgaa agacaaaatg acagctacaa atatctaatg atttattaga tttaagattt
     4561 ataaaaggca gaaaggctaa tattttatga acaatatata ctcaaaaact aaattacaag
     4621 aaaatagtaa ggataaagtt tttgaaaata gttatagtct agtggactac aaatatttaa
     4681 attcttttaa tgtagaagta agcaaaataa atgaacatga agtatcaata gataatgaag
     4741 aaataattgc agaatatcca cttagtttta ttttaaatga taaatatata aatacatttt
     4801 tatgtacccc atataattta gaggaactta tagtaggatt cttgaaaaca aaaggataca
     4861 tagaaaacaa aaaaagctta ttaaaatttg agataaatga gagtgaacgt tttgcaaaag
     4921 taactattca agagaaacaa aaaaatcaag atgagcaaat tatattttta aattcactag
     4981 actatataac atgtgctcct gtaaagagca atataaaaat aaattatgat acgatttaca
     5041 gtataatgga taaaaattta aattcatcag aattatttaa aaatactggt ggggtacata
     5101 gtgtatctgt atttaatttt gataaaaaaa tagtcacttg tgaagatgta gcaaggcata
     5161 atgcaatgga taaggctatt ggattttgtg ttttaaatga cataacatta aaagataaaa
     5221 ttgtggctgt aagtggaaga atatcattgg aaatgatatt aaaagcagct atgactcaaa
     5281 ttcctattgt agtatcaaaa tcagcaccga ctaatttatc aatagagctt tctaaaaaat
     5341 taaatataac gcttattgga tttgtaagag gaagacggat gaatatttat gcaaatccac
     5401 agagagttat caaaaagtga gaatgaatat atgtgtacta aaaaagaaga gcaaagatat
     5461 tcaaagtgtg aaatctgtgg agtattaatt gatgatactg ataaggtata taataacaca
     5521 tacaatttgt gcaaaaaatg taaacgaaat ataagtactg agaaaatagt gaaatatata
     5581 aatatatatg atgaaaataa ctagagggtt ggaaatatac aaattgaaag gtgggataat
     5641 atgaaaaata aaataggctc ttttgtaata gcagacccaa acaaatgtac aggttgtaga
     5701 gcttgtgaag tagcttgttt tacaatgcat aatcagcata ataatgtggg ttatacagtt
     5761 ggaacagttg atatacctgt tatacctaga ctttacttag taaaaggtga caatttctgt
     5821 atgccaatac agtgtagaca ttgtgaagat gctccttgtt taaactcatg tccacaaaaa
     5881 gctatagtta aagaaaacaa tattatgtct gtaaatgaag aaaagtgtat aggatgtaaa
     5941 acttgtctgc tagcatgtcc ttttggagct atagacttac ttccacaata tgaagatggt
     6001 aaagaagtag aacaagtaat tttagatgaa aataagaaga tagcttataa atgtgactta
     6061 tgtaaagaca atgaaaaaat agcttgtata agtgcatgtc ctcaggaagc attaaaactt
     6121 gttactccaa tagatgacaa aaaagctaag aatagacaag ctgcacttag tttattgtta
     6181 acaaataaat aaaggataca ggggtaggtg acgtttatga taataaatat agataaggat
     6241 ttatgtactg gatgtagaga atgttcaaag gtctgtccag taaatgctat tgaaggtgaa
     6301 gagggaaagc cacaagagat aaatttagat agatgtgtta tgtgcggtca atgtgttcaa
     6361 acttgtaaat cttatgcctc agttatagat gaaggatttg agtttttaca agagaaaaaa
     6421 caagaaagag agataccaga gtctataaat gaacctatat ttgcagcata caatgtatgt
     6481 gatatagata aggtgaagaa agctttaagt gacccaaatg tattcactat ggtccaatgt
     6541 gcaccagcag ttagagttgc tttaggagaa gatttcggat attatttagg atacttaggt
     6601 gctgggaaaa tggcagcagc acttagagct ttaaattttg atagagtcta cgatactaat
     6661 tttgcagcag atttaactat aatggaagaa ggtagtgaat taattaaaag agtgacagaa
     6721 ggtggaactc ttccaatgtt tacatcttgt tgtccagctt gggtaaaatt catggaaaaa
     6781 aattatccta aattaactaa tcatttatct tcttgtaaat cacctcagca gatgggtggt
     6841 gcaatattta aaacttatgg tgcagagata aataatgtag atgcatcaaa gatatttagt
     6901 gtttctataa tgccatgtac atgtaaaaaa tatgaatgtg atagagaaga aatggattct
     6961 agtggatata gagatgtaga tgtagtatta actactagag aactagctta tttaataaaa
     7021 gacatgggaa ttgattttaa aaatttaaga gaagaaaaat ttgatagtcc tttaggtagt
     7081 tatagtggag ctggaactat ctttggtgtt actggtgggg ttatggaagc tgctataaga
     7141 acaggatatg agcttataac tggagaaagt attcctgatg tagaagtaaa acaagtaaga
     7201 ggagaaaatg gttttagaaa gtcaactatt aaaataggag acttagactt aagagttgga
     7261 gtagtaagtg gattaaaaaa tgtaatacca gtgcttgaag acttggaaaa aggaaaatta
     7321 gatgtagatt ttattgaagt tatgacttgt cctgttgggt gtgtaagtgg tggaggtcaa
     7381 ccaaaaattt tactagaaga atataaggaa ttggcttatg aaaatagaac aaaagcaaca
     7441 tacgtgcatg atgaacattt agcaattaga aaatctcatg agaatcctga tattaaaaaa
     7501 ctgtatgatg aatatctggt agaaccatta ggagaaaaat ctcatcatct attacacact
     7561 acatattgta taggaaagga agtggctaag tgatgaacta ttttgttata gcagaccctg
     7621 ataaatgcat aggatgtaga acttgtatga taggatgtgt agttgcacat tcagatgaag
     7681 atatttttta ccaaaatcca gatgaaataa attttaatcc aaaactttct gtcataaaga
     7741 caaaagaagt aagtgctcca atacagtgta gacattgtga agatgctcct tgtgcaaagg
     7801 catgtccaaa tggtggtata gttagggttg gtaacacaat aaaaatcaat gaagaaaatt
     7861 gtataggatg taagacttgt atgttagcat gtcctatagg tgcaatagac atagttacat
     7921 taaaagatgt agatgaagga aagctttgct ttagagaaag aatgacagca aataagtgtg
     7981 atttttgtat agaatcgcca gaagggcctg catgtgtaaa tgtttgtcca actaaggcat
     8041 ttactatagt taaggatgag gatatagata gtaaagttaa aaataagaga aaattagcta
     8101 tattgtaata taaaaaagat ggagttttat ttatgattaa aagctccatc ttttttatta
     8161 taatatttat atatctaaaa atcaattatt gcattagttt atctaatctt tctttattca
     8221 attttttcat tcctatagaa gttataataa gtaaagtata ggcaattata actgataaaa
     8281 ttataataga ccaagaaaat ctgtatccaa aattatcaac taacaatcca aataatgttg
     8341 aacctaatgc aaatcccact gcaaaaatta attgtacgat tccatatatg ctaccaaact
     8401 ccttttgacc aaagaaagag ccagttaaat aagcaggacc aatcatataa gcaaatacag
     8461 aaagaccttt caaaatggca aatacaaatg caaaagtaga agatttatct accaatagta
     8521 atgataaagt tgctataaga accaatacaa aagatataat aagtggcttt gtttgaccga
     8581 atttatcaaa caataatcct ccaaataaat taccaatgag agcaaataaa gcaaatgtgg
     8641 agcctactgt tcctattaga ataggattta gataatttct aagataagtt ggatattgta
     8701 cagataatga tgaaacatat ataccaacaa atataaatcc aatagtcata atccaaaaat
     8761 atttaatttt tttagcttct tttaatgtat aaccccatac tgaaggagaa attttatcag
     8821 atgctttctc ttttttacct ttagatttta ccttttcatt aatatcttta ggcatcctga
     8881 gtataaataa tattacaggt ataccaacta ttaatgctat aattccaaat attagataag
     8941 aacgactgta tccttgagtt gctaataagc gaactgcaag tggttgtaga aatatactac
     9001 caatagaacc accagcaaaa gcaaagccca aagcttttcc tttgctttct tcatcaaacc
     9061 aagcacttat taaaacaggt attcctatag cagatataat tgtagcgcca atttgaacaa
     9121 tacatgatac agtgtaaaat tgccatagtt cagtacatat agaaaaagta gcaaaagcaa
     9181 tactagaaat tatacaacct aataaatata gtatcttaat attgacttta gaaaataata
     9241 cacctataaa aggtgatgca attgctgagg caatagtacc aatagtgaat attagagaaa
     9301 aagaagctaa actaaagcct tctccttcta caacataact tataaattga ggctgtatac
     9361 ttgctacaat actaaatgga acagcttgta ttaacataca accaagtact ataacccaag
     9421 catttgaaaa gtttttaatg ctaaatttat tgtttagtaa tgtattcatg gtatctctcc
     9481 tttaggttat gatttgtaga tattaatcta attattctaa ttttatatat tagttttgga
     9541 tagcctaact atttaaatat aatttgggta ttaatataaa aattaactat aaaaattgat
     9601 tattttaaat gtatggggta aattaaagta tataaataaa tgaaaggatg gataaaatgt
     9661 catttgaaaa aataaataat aataacctag ataaaataca caacaggaag tgtattatgc
     9721 ttgtaaactt taataaaaaa gaattatcat taattaaaaa cgtaagtaac tttgctggaa
     9781 taagagacca tatcatctta agtgataaaa atggagagaa tataataaga gacattttag
     9841 atggaaatat atcaaatgaa tgtgaaaatg ggattaagag taagtctgta atatttaata
     9901 acactccaag cacacaagta aatgcatttt tagaagggct aaaaaaagtg agaataaata
     9961 gaccttttac agctatggta acagagacat ctattgattg gacattgaat aatttaatag
    10021 aaaatttagt tcaagaacgt aatgctatgt ctttaggaaa aacaattgaa cataagtaaa
    10081 tttaagatat cttatagtaa ttttaactaa tgtacattga gtatcatatt atattttaga
    10141 atataaaatt ttaaatgtgg gtagatggag gagatttgag atgaaagttt tatttacaat
    10201 aaattatgga aaagaaaaat ttgataaaat aagagaatta ggctatgatg tcatacatta
    10261 ctctgaagat agtattgaaa ataatgagga tgtaaataca gcagatgtac tagttacata
    10321 caatccattt gagagattag atatttctaa gatgaaaaat ttacaatata tacagacaac
    10381 tagtgtaggt atagaccaac ttccaaaaga agaggtattg aagagaaata ttaagatagc
    10441 taataataga ggcggatata gtgtacctat tggtgaaagt attgtattgt atattttaga
    10501 aatatataaa aatagtgcaa aattttttaa acaacaacaa aataaagaat ggaagatgga
    10561 tttttctgta tcagaattgt atggacaaag agttggattt ttaggaacag gtactatatc
    10621 ttcagaagca gcaaaaagat taaaagcttt tggtgtagaa atatggggtg tcaatactga
    10681 tggaagtagt aaaaaatact ttgataagtg ttttgctact gaggatatga atattgtatt
    10741 tgaagaatgt gatatagtag ttgtagcaat gccttctaca aaaagtacag atggaatagt
    10801 aaacaaagat atgtttaaac ttatgaaaga tggttctgta tttataaatg taggtagagg
    10861 aaatacagtt aatcagaaag atttagaaga atgtgtagag aaatttagag gggtagcatt
    10921 agacgtattt gaaagtgaac ctttaaacaa ggacaataag ttgtgggagt gcgaaaatgt
    10981 catagtaact cctcataatt cttgggtgtc agataaaaac aaagagagaa catttaatat
    11041 ggtttataat aatttgaaac actatataat ggagaataaa cctgtagata atgttgtaga
    11101 catatcaaga ggctattaaa aataaaaaat tttgataaaa ataaaaactt ttattagtcg
    11161 tattaaagat actaataaga gttttttttg taataaattt aaagccaaaa aagtgatata
    11221 ctaaaaaata tataaatagg agataattaa ttatagggaa atttcaaaat aatttaattt
    11281 taaaaatatg aagaggtgca aaaagtgagc ataaaagatg aaattaataa acttatagag
    11341 acaataaact accataatga aaggtattat aatcaagata gcccagaaat atcagattat
    11401 gaatacgata agttaatgaa ggagttaatt tctttagaag aagaacatcc agaactaaag
    11461 agaattgatt ctccaacaaa tagggtagga ggtaagccat tagataagtt caatcaaatt
    11521 gtacataaaa ctcctatgtt gagtttatca aatgcttttt cagagcaaga tttgagagat
    11581 tttgataaga gagttcaaga atatgtggga gaaaatgttg aatatgttgt tgaatttaaa
    11641 atagatggtc tttctgtagg tctaacttat aacaatggag agtttgaaaa aggagcaact
    11701 agaggagatg gagttgtagg agaagatatt tctcaaaact taatgacagt aaaaagcata
    11761 cctcttaaga taaatgataa aaaagaacta atagttagag gagaagtata tatatcaaaa
    11821 gataatttta gaaaagtaaa tgaacaacaa gaagaacaag aacagccatt atttgctaat
    11881 ccaaggaatc ttgcagctgg ttcattgaga caattagacc caaaactaac agcaaagaga
    11941 ccattagata tatttgtatt taatatggaa aatatagaag aatacgattt agaaagtcac
    12001 agtgaatcac tagagtactt agaaaaacta ggattttcag taagtcagag ttataaagtt
    12061 tgtaaaagta tagatgaagt tattgagcat attgaatact ggacagataa caggggtaat
    12121 ttagactacg aaatagatgg tatggtaata aaagtaaaca atataaaaca aagagacgaa
    12181 atgggatata cagccaaaag tcctagatgg gcaattgcat ataaattccc agcagaaaag
    12241 aagaaaacta aaatagtaga tataatagta gaagttggga gaactggtac aataacacct
    12301 tcagcaattc ttgaaccagt cagacttgca ggtactactg taagtagagc tacacttcac
    12361 aatgaagatt atataagaga aaaagatata aaaataaatg atacagtatt agttcaaaaa
    12421 gcaggggaca taatacctca agttttagaa gttataaaag aagaacgtac tggagatgaa
    12481 atagatttta aaatgccaga aaagtgtcca gtttgttcag agccaacaat aagattagaa
    12541 ggagaggctg ctgtaaaatg tatcaatatg tcttgcccag cccaaataag aaggggaatt
    12601 atacactttg tgtcaaggga tgcaatgaat atagatggat tgggagaatc tataattaca
    12661 ctgctattaa atgaaaaaat tattcaagat gtatctgatt tatattatat aaaaaaggaa
    12721 gatgtagtcg acctagagag aatgggcgaa aaatctgctg acaatttaat aaattcaatt
    12781 gaaaaatcaa aagaaaatga tttatggaga cttataaatg gattaggtat taaatttata
    12841 ggagttaaag cagctaagat acttgcatat aactttaagg atttagatga agtaatttct
    12901 gcaactagtg agcaactaga agaattagag gaatttggaa gtataatggc aaacagcgtt
    12961 gtcgagtttt ttaaggaaga caaaaatatg aacgttataa acaagttaaa aaatgtagga
    13021 gtaaatacaa aatcattgga taatacaggt gaaaaagtag aaaaaatatt tgaagggatg
    13081 aaaatcgtat tgactggtac acttcctaca ttaaaaagaa atgatgcaaa agatatgata
    13141 gaaaaaagag gtggaaaagc tacatctagt gttagtaaat cgacaacatt tgttttggca
    13201 ggtgaagaag ctggttctaa acttactaaa gcaagtgatt taggaattaa agttatagat
    13261 gaagagagat ttttagaatt attaaagtta tcatcgaaag atgaagtaaa agctgtatta
    13321 gagagttaaa aagtcgctta atttagtaga aaactactat aattaatgat agaatagttc
    13381 agtaagctaa taagattacg aaaaatgaca ataattaata tttgacaaaa ttaaaaatta
    13441 taaaaataaa tttataaaaa ataaaaaata tgagaaagga tataaaaaat gaccagaagt
    13501 tatgatagaa gtaatgaaca gataagacct gtaaagataa ctagagatta tacaaagtat
    13561 gcagaaggtt ctgttcttat agaaatggga gagacaaagg ttatatgcac tgcatcagtg
    13621 gaagaaaaag ttcctccttt tttaagaaat agtggtactg gatggataaa tgctgaatat
    13681 tctatgctac caagagcaac acaacaaaga aagataagag atgcatctag gggaaaaatt
    13741 gatggaagaa cacaagaaat acagaggtta ataggaagag caataaggtc tgttgtagac
    13801 ttgaataaat taggagaaag aactatttgg gtagattgtg atgtgattca ggcagatggt
    13861 ggaactagaa ctgcatctat aacaggggca tttgtagcag ttgcagaagc aatatataaa
    13921 ttatataaag caaagacaat aaaagagatg ccaataacaa attttgtatc tgcaattagt
    13981 gttggtattg taaatggaat acacatgcta gatttatgtt atgaagaaga ttctaaagca
    14041 caggtagata tgaatataat aatgactgat aagtgtgagt ttgtagaagt acaggggaca
    14101 ggagaagaga aacctttttc gagagcagat ttaaatttat tgttagagtt aggtgaaaaa
    14161 gggaataaag aattaataag gcttcaaaga gaagctttag gtgaaatagc agatgagata
    14221 ttgggtatgg attatggtaa tgaagtagtg attgctacta ataatgctca taagctagaa
    14281 gaaataggtg aaatcttaaa agattttgaa tataaagtgt actctttaaa agatgttgat
    14341 ttagcaggta tagagatagt agaagatgga aaaacatttg agcataatgc gttgataaaa
    14401 gctagaacaa tagcaaaaaa gactaaactt atagcaatat cagatgattc tggcttagaa
    14461 gtagatgctt taggcaaaaa acctggtgtt tattcagcta gatatgcagg agaacatgca
    14521 acagatgaag aaaatagaaa aaaactgtta aaagctatgc aaaatgtacc aatgagcaaa
    14581 agaaatgcaa gattcgtctc tgcaatagca gtagtttttc ctgatggaaa agaatttgta
    14641 gtaagaggaa tttgtgaagg aatgatagga tttgaagaaa aaggtaaaaa tggttttgga
    14701 tatgatagct tatttatagt aaaaggatat gataagactt ttggtgaaat acctagtgtt
    14761 ataaaaaatt caatcagtca tagagcaaac gcactaaaac ttatgaaaca agagtttata
    14821 aaaagggtag tgaagtaatg aaaataggca tagtaagcga cacacatatg atgattaaaa
    14881 atatggaaaa aacaatacca tatttgaaag aatgtgacct aataattcat gcaggagata
    14941 actttactga ttcaagatat attcatagca tgactaatgt aggtattatt gcagttaaag
    15001 gtaattgtga ctttgatgct gttgaggaag aagttgtctt tgaagtggca aataaaacca
    15061 tattcttatg ccatggagat aagtatggtg taaaatatgg aactaatatg ttagaaaaaa
    15121 aggcaactga agttgatgct gatatagtta tatttggcca tacccatacc ccatttagag
    15181 aaattaaaga tggtgtactt tacataaatc ctggaagcac ttcacttcca agaggagtat
    15241 cgtataaaag ttttgtcatt atgaatatag aagaagatga cataaaaatt gaagaaatac
    15301 gcatataaag gtgtatttat ctaaaaaaat ggcaaaaaac gctcaaaaaa ttaaatttta
    15361 tcaaataagt acaacgatat taatggaaca cttgtaaata aaaaaactta tgtgatataa
    15421 ttaagtggtt gaattataaa tagaatgaat tataataccg ttatcgggta ttacataaat
    15481 atcactagga ggattagaag gatgaaagca gaactaatta aaaaagaggg taataaagtt
    15541 actttaaaaa taacagtaga taacaataaa tttgaagcag cagtaaataa ggcttataat
    15601 aaaagcagaa ataaatacaa tatacctgga tttagaaaag gtaaagctcc aagaattgtt
    15661 atagagactc aatacggaaa aggtatattc tacaatgatg ctatagaaat attattccca
    15721 gaagtttatc cagaagctat caaggaatta gacatagacc caatagacaa tccagattta
    15781 gatatagaag aaataagtaa agacaatggg ttggttatgg ttcttaatgt agaagttaaa
    15841 ccagagtttg aattaggaaa ctacaagggt atagaaatag ctaaggttga gaatactgta
    15901 agtgacgaaa atgttgatgc taaactacaa gaaatggttg aaaaaaatgc cagattagta
    15961 agtgtagaag acaaagcttt agaagatgga gatacagcta taatagactt cgaaggtttt
    16021 gaaaatggtg tagcttttga tggtggtaaa ggtgaaaatt ataacttagt tataggttca
    16081 aacacattta taccaggatt tgaagaacaa ttagtaggta aaaaagctgg tgaagaagta
    16141 gaagttaatg ttactttccc agaagaatat cactcacaag atttagctgg aaaaccagtt
    16201 gtatttaatg taaaaataaa tgatgtaaaa gtaaaagaat tatctgcact tgatgatgaa
    16261 tttgctaaag atactagtga atttgattct ttagatgaat taaaagcaga tgtaagagct
    16321 aatttagaag aagaagctaa aaatagagca gatgcagaaa ctagaaattc agtagtagaa
    16381 aaagttgctg aaaatacaga aatagaaata ccagaagtta tgatacaaca tcaaatagat
    16441 aatatgttaa atgaacttaa ctaccaatta caatatcaag gatttggatt acaacaatta
    16501 ctagagatga ctggtagaac tatggaagaa ttaagagaag agagaaaaga agatgctaaa
    16561 aaattagtta agtcttcttt agtattagaa gcaataacta aagctgaagg aattgaagca
    16621 acagaagaag aatttaaggc tgagttagaa aaaatggctt ctgcttacaa tatggaagta
    16681 gaaaaaatag aagcttcttt aagagatgct gacaaagaag atataaaagg tcaaataaaa
    16741 ataagaaaaa caatagattt attagttgat aatgcaacaa tagcttaata aaataaacgc
    16801 taactaatat agttgacgtt atgaaatgtt tagtatataa tgatgtgcaa atataattta
    16861 gttaaatgcg tataataatt tacagtagct taaaaaaagc tactgtaaat tatatagaat
    16921 aaagggggta taaaaccatg gcattagtac ctgtagttgt tgaacaaaca ggaagaggag
    16981 aaagatctta tgatattttt tctagactat taaaagacag aataatcttc ttaggagatc
    17041 aagttaacga tgccacagca gggcttatag tagcacagct attattttta gaagctgaag
    17101 acccagacaa agatatacat ttatatataa attctccagg aggaagtata acttctggaa
    17161 tggctatata tgatactatg caatacatca aaccagatgt aagcactata tgtataggta
    17221 tggctgcttc tatgggagca ttcttgttgg cagcaggagc aaaaggaaaa agactagcac
    17281 taccaaatag tgaaataatg atacatcaac cattaggtgg agctcaaggt caagcaacag
    17341 atatagaaat tcatgcaaag agaattttaa aaataaaaga gactctaaat gagatattct
    17401 ctgaaagaac tggtcagcca ttagaaaaaa ttaaaatgga tactgaacgt gataacttca
    17461 tgagtgcact agaagccaaa gaatatggtt taatagatga agtatttaca aagagaccgt
    17521 agatagagag aggtgttaat atgtctaaat atgaagaaaa acgacaatta aagtgttcat
    17581 tctgcggtaa aaatcaagat caagtaagaa gattaattgc aggtccaaat gtatatattt
    17641 gtgacgagtg tgttgaactt tgtgacgaaa ttattcagga agaaatagaa gatactatag
    17701 atgaagatac tacatcttta ccaaaaccaa aggaaatgat ggagattcta aatgattatg
    17761 taataggtca agaaaaagct aaaaaagctt tatcagttgc ggtttataat cattataaga
    17821 gaatatacag taaaaaatct agtagtaagg atatagaaat tcaaaagagt aatatacttt
    17881 tattaggacc tacaggttct ggaaagacat tacttgctca aactctagca agaactctaa
    17941 atgtaccttt tgcaatggca gatgctacat cattgactga agctggatat gttggagaag
    18001 acgttgaaaa tatactttta aaacttattc aagctgctga ttttgatata gaaaaagctg
    18061 aaagaggtat aatatatata gatgagatag ataagattgc aagaaaatct gaaaacccat
    18121 ctataactag agatgttagt ggtgaaggtg ttcaacaggc acttctaaaa atattagaag
    18181 gtactgttgc aaatgttcca ccacaaggag gaagaaaaca tcctcatcaa gaatttttaa
    18241 agatagatac tactaatgta ttatttatat taggtggagc ttttgatgga ttagagaaga
    18301 taattcaaaa acgtggtgga gataaaacac taggttttgg agctaaaata gaaagtaaaa
    18361 aagaattaga tttagggaag ctatatgaaa aagtacttcc agaggattta ttaaaatatg
    18421 gtataatacc agagtttata ggaagaatac cagttttagc tactttagag ttgttggatg
    18481 aagatgcatt aatgcagata ttacaggaac ctaaaaatgc tctagtaaaa cagtataaaa
    18541 agttattgga gttagatgat gttgagctag aatttgaaga aggtgctctt cgtgcaatcg
    18601 ctaaaaaggc catagaaaga aatacaggag ctagaggact tagaagtata gttgaaagcg
    18661 taatgatgga aactatgttt gaagtaccat ctagagataa tataaagaag gttatagtaa
    18721 cagagaaatc tgtgaacgaa gactcagtaa atcctatcat agtacttaag gatcaagagg
    18781 aaagtgcata agatgatgaa aaggagcttt aaaagctcct ttttttatgt taatatgcta
    18841 aatataaaat aggtatcatt attataaaaa tgtgagtaat atacctagaa taccaaagac
    18901 gaatacaatt gcaatggaac caatttttcc tttatataaa agataaaatg atgctataaa
    18961 tgcaattatt ccatataaat cccaattaac ttctttggca gatgaaaaag ctgctgataa
    19021 tatgaatcct agagtaattg gtctaagaac tgtcaataaa ttttctacct ttttattatt
    19081 tttaaattta gaaaataact ttgatataat agttagacct attaatgcaa aaattgtaac
    19141 accaatagtt gcagctagag aaccaaagaa gccagcagtc ttaaatccta caaatgtagc
    19201 actatttatt gctacaggac ctggtgtaga ttgtgatata gcaagtaaat ccaaaaactc
    19261 ttgattagtt ataaagtgat atttagatat aaattcttgc tggataaatg gtagcatggc
    19321 ataaccgcca ccaaaactaa atgcccctat tttaaggaat attaagaaga gtagtattat
    19381 ttctgacata gactatatac acctcctcca attattaaat aaatagggct tatattgaat
    19441 acaccaacag ataaaactgc tataattaat agtagtatgt tagttttaga ctttggtagt
    19501 ttcttgaaca tgctcgtaaa agaatacaat ataagagcta ttacaacagg cgcaactcct
    19561 ttaaaaaatc catctaaaat tttagatgat gaatttttaa agtatagata cgataagact
    19621 aagactatac aaaatgatgg taaagcagag cctaaggtac atataagaac tcctggtata
    19681 ccataaagtt tatatcctaa taatacagat atattaactg ccagtactcc aggataactt
    19741 tgagctatgg ataaataatc aataaattct tcctgctcta aaagtttttg tttgtttaca
    19801 agttcatctt gtataagagg aaccatagcg tatccaccac caaatgtaaa cgcaccaatt
    19861 tttaaaaagg ttaaaaacaa tttcaacata atagaaacct ccaaaagata aataacatct
    19921 aagtatacta atattaatat tatatcataa taaaaagata atatagtatg atagtattct
    19981 aagaatttat cattaatgtt gaaaattaac ttgttcaaat atataatatt aaaagcaaag
    20041 caattagact agaaaaggag taatgttgat ggaacaaaat tatactaaaa tagatcatga
    20101 attaccatta attcctctaa gaggattagc tatatttcca tatatgatat taaattttga
    20161 tataggtaga gagatatctc ttaaagcttt agaccaagct atgatggatg aagaacttat
    20221 atttttaact tctcagaaag aagcagaggt agatgagcca ggagaagagg atttttatca
    20281 tgtgggaaca atctgtaaag ttaagcaaat gataaaatta ccaggagata cagttcgtgt
    20341 tttggttgaa ggtgtatcaa ggggtagagt aaagaaaata gaacaagaag atgggtattt
    20401 cagagcagta atagaagaaa tagtatttga tagtgataat ttggatagtg aaacagaagt
    20461 tgaaattgaa gcatttgtaa gaaatgtatt tgatgccttt gaagagtata taaatattgg
    20521 aaatagggta tcaccagaaa tattaatatc tttagctgat atagaagatg tagatagatt
    20581 tatagatacg atagctgcaa acatatatct aaaatcaagc caaaaacaag aaatattaga
    20641 agaatttgat attagaaaaa gacttgaact tatttattct atattattag aggaaataga
    20701 tatattaaaa atagaaaaga aaataacttt aagagtaaaa aaacagatga ataaggttca
    20761 aaaagaatat tatcttagag aacaattaaa agctatacag aaagaattag gtgaagaaga
    20821 agatataaac tctgaagcag atgagtatag agaaaagctt aaaaaaataa aagcacctaa
    20881 gacaactaaa gagaaaatag aaaaagagat agataaattt tcaaaaatat cttctatgtc
    20941 tccagatgta tctgtaagta gaaactattt agatactata ttctcattgc catggaataa
    21001 agagacaaaa gataaattag atataactaa ggcaaaagat atattagatg aagaccatta
    21061 tggattagaa aaagttaagg agagaatact agagtatcta gctataagaa ctcttgctaa
    21121 gtcacttaaa ggtcctataa tatgtctagt tggtcctcca ggaacaggaa agacatctat
    21181 agtaaaatca atcgccagag cattaaatag aaaatttgta agaatatctt tgggtggagt
    21241 tagagatgaa gcagaaataa gaggtcatag aagaacttat gtaggttcaa ttccaggaag
    21301 aataattaat ggggtaaaag aagcccaaac aaaaaatcct gtattcttat ttgatgagat
    21361 agataagatg gcagcagatt ataaaggtga cccagcttca gcaatgctag aagtattaga
    21421 cccagagcaa aataaggatt ttgtggacca ttacttagaa ataccttttg atttatcaaa
    21481 aatactattt gttacaacag caaatagtct aggtaatata ccaagaccat tattagatag
    21541 aatggaagta atagaagtat ctgggtatat agaagaagaa aaattaaata tagcaaaaaa
    21601 atacctactt ccaaaacaga ttaaagaaca tgctttaaaa gaaagcttta taaaaataga
    21661 tgatgaaact ttaagaagta taatcaacca ttatacaaga gaagctggag taagaacact
    21721 agaaagaact attggtaaga tttgtagaaa ggttgcaaaa aaatacgttg aagacccaac
    21781 tcttgaagag gttgttataa ataagtctga cctagagaca tatcttggaa aagacatgtt
    21841 taagtatcaa cttgcagaag ttaaccctca aataggatta gtaaatggtc ttgcatggac
    21901 agaagttggt ggagttacac ttgaagtaga agtaaacgta cttaaaggta aaggagaaat
    21961 tgtattaact ggaaaattag gagatgttat gaaggaatct gcgaagacag gtatctctta
    22021 tataaggtca atagtggaca agtttgatat agaccctgaa ttttataaga cgaatgatat
    22081 tcatatacac attccagaag gtgctgttcc aaaagatgga ccatcagctg gtataactat
    22141 ggctcttgca gtaatctcag cacttactaa aagacctgtg cctggaaata tagcaatgac
    22201 aggagagata actttaagag gtagagtctt agcagtagga ggagttaaag aaaagttatt
    22261 agcagctcat agagctggta taacaaaagt attaattcct aaagaatgtg aagctgattt
    22321 agatgaaata ccagaaaatg taaaagaaaa aatggagttt gtgcttgtag aacatatgga
    22381 tgaagtatta gaacaagctt tattaaagag tggtgaaaat aatgaaaatt agaagttcag
    22441 agataactat gagtgctgtg aataaatcac agtatccagc agaaggaatc ccagagatag
    22501 cattggctgg taggtcaaat gttggaaaat catcaataat aaatacattg cttaacagaa
    22561 gaaactttgc tagaaccagt caaacaccag gaaaaactag aactataaat ttttatctaa
    22621 taaataatga attttatttt gtagaccttc caggctatgg atatgcaaag atagctaagt
    22681 ctgaaaaaga aaagtgggga ggtataatgg aacgatatct agaaagtaga caagagttat
    22741 gttctatatt cctacttgta gatattagac atgagcctac agcagatgat aagcttatgt
    22801 atgaatggat aaagcacttt ggatataact gtgtagttat tgcaactaag gcagataaaa
    22861 tatctagagg acaatatcaa aaacacataa gtataataag aaaaaaattg caaatggaaa
    22921 gtagtgaaaa agtaattcct gtttcttcac taaaaaagac tggtgttgaa gaattatggg
    22981 aagagattgt aaatcaatac aatcaacatg gatatgaaat aacagtagat taaatttaaa
    23041 atgttaaata ttgacataag atttgtttga ataataaatg taataatagt tagttttaat
    23101 tatattaata ttaaagcaaa atataggatg ccttaaaata gttttaatga actttttttg
    23161 gcatccttat tgtttataaa caataaatat cagtaatttt gctaaatact aataaatttt
    23221 agtaaggtat gggaaaatta gtataaatta gttcaactaa aaaattattg acttatgtag
    23281 tcagcaataa atagcattta agaaatagat ttatctgttt ttctcataaa gaaaacagtt
    23341 agtataagcc ctataaaaca tactgatgct gcaatccaat aagactgatt gctagctata
    23401 acataggctg atgtgtgact tttaaacttt tgattgtatg taagactttg tgcaaaaaaa
    23461 ctactaaaaa atgctgttcc aagagcaaat gataaattac gaatagttgc aagaaaactg
    23521 cctccgtatc cctgtttttg aggaggaaca tctgctaaaa tactactatt gtttggtgaa
    23581 ctaaatgctc ctagcccaag tccaaaaata actaaacata caattaaaag atacaatgga
    23641 gaatctgctt ttaaaagtgc cattccaact agtgagatgg tcataaatga aaaagatgct
    23701 gttagaatgt tttttgcacc gtgtttatca gaaagtgaac ctgcaatagg tgctataagt
    23761 accataataa gtggatgtac agtcattaca taaccagcca tcataggaga taaatttttt
    23821 aattgttcta aataaaatgg aagtagaaaa gatactgcca tttgaggaaa ataacaagct
    23881 actccaatga tattgcctac agtaaagttt ctatttttaa atagaggtag gtcaataaag
    23941 ctttgttcaa attttacttc tcttaatgcc aacaataaga agattataag tgctgttata
    24001 cctaaataca atcttgtatt acccttctca ttcattgcaa gtaatataag cgtagtgcaa
    24061 gatgcgaaaa gtagaagacc tggaatatca aagctcttgt tttgttcatc caaaacaggt
    24121 ttaggcagaa atttaatgcc aagaaagact gctataatac caataggtat attgataata
    24181 aaaatagaag gccatccaaa atgttctaaa attatacctc caattacagg accactcata
    24241 tttcctatac caactacagc tccagtgatt cctatagctt ttcctttttc atttgctgga
    24301 aatgcattgg aaactatacc aagcccagta gccattaaaa tacttgctcc aactgcctga
    24361 aagattcttg aagaaattaa tgttgataaa ttgtttgaca tactacacag aaaagaacct
    24421 attgtaaata taaaaaatcc taatgtgtat agacgatttg aacctacttt atcgccaagt
    24481 tttccgaaaa ataacatagt agctgttaca acaagcatat aagctgttac aacccactga
    24541 atttgtgaca tgttaatttt aaagtcagca gcaattgtag gatttgcgat atttagtata
    24601 cttccatcaa gagtagacat aaatacacca atacagatga taatcaatac tatccatttt
    24661 tgtttcatga taacactcca atcttaatag attttataag tacgatataa ttgtaaaata
    24721 aacaacaaaa aaagcacctg tatattaggt accttgaata tgtctaattt catgaataaa
    24781 tacggtagtt gaaggatttg tatagattac tcatgtaaaa ttacataaag gtactcatat
    24841 actattttct tctaccatcc agattttact gtcggctttg gaatatgacc aaattatgcc
    24901 ataaggctcg cgggctttta ctgccgatag ggaatttcac ccgtttatga agaaaaacag
    24961 atgtattttg taatattatt ttaacataaa attataatgg aaacaattgg atttaagtaa
    25021 tatccagctg tattacaata caaatatttc aatatggaca cttaaattgt atttatagat
    25081 agaataagga acagtatgag aatctataat aattagataa aattaacctg ttattagtat
    25141 tagatggcaa gttttaaatt tatcaaaatc agaaagctgt aataaaattc ttataatatg
    25201 aatatcttaa ttaagagata ttgtaaatta tgaggaggcg ctaatatgga aggaaaggta
    25261 aagaaggcat tcccgggtgg aaatacatca caaggctcat attctttttt tgactatata
    25321 attcctgaaa atgtaaaaag agttttttgt ttaaagggtg gacctggagt aggaaaatcc
    25381 tcacttatga aaaaaattta taaagagttt ttgcatagag gatatgatat tgatttatat
    25441 cattgtcctt ctgacccaag ttcgttggat ggtttagtta taaagaaatt aggcgtggta
    25501 cttatggatg caactgcccc acatactatg gacccaaagc tacctggagc tttggatgag
    25561 ataattaatt taggtgatta ctggaataca gaagaattag aaaagaataa acaagaaata
    25621 tcagtttatg ataaagatat tagtaattca tttaaaagag catttaagtt tttaaaatca
    25681 gcagaaccaa tctttagaga catagaagaa aaatattctg attgtatgga ttatggaaaa
    25741 gtaaatttgg tcacagaaga atttataaaa aggttatttg atggagttaa aagcacagga
    25801 aatctaaaaa gagaaaagca tttatttggt tcagctataa ctcctgtagg gtgtttagat
    25861 tatacagaaa acattttaaa agatgtaaag aaagtctatt atttagatgg agaaatagga
    25921 actgggaaaa ctacattatt aaacaaagta tataagaaag ctattgaaaa aggtttaaat
    25981 gtagaagttt atcattatcc acttattcca gagaaaattg aaactgtact attaactgat
    26041 ttagatatag gcataactat aagtacgact tttaaagaag aagatacaat tgatttaaat
    26101 cagtttttaa atagagaaaa actacttaaa tatgaagaag atattaaatt tgatgaaaaa
    26161 gttttagatg atttaatttg ttgggcagta ctaaatctta agagagccaa gtctaaacat
    26221 gatattatag aaagttacta tagtcctaat atgagatttg atgaagtagg gaaattaaga
    26281 gataagttaa ttaaaagaat tttaaaatat gaggaaaact tataaacgta tatgtttaaa
    26341 attaatgtta ataataatat aatttttagt aaattggtgt agctttgagg ctatgccatt
    26401 ttactttttt tgctaaaaaa tgatattaat aatctccaaa gtcattattt gtttttcata
    26461 attattattt ccgttcctaa tttatgtttt tttataatat cacaacaatg tttattgaaa
    26521 gtttatataa ttttaagaac atctaaaaat gcatacttga tattggtaaa ttagtgatag
    26581 gagttcaatg tatgatatta tatactaaag atgaatttta atatataact ttgatataat
    26641 aagcatatgt aaatgtttaa tatttaatta aagaaaatta tcatataaaa ataaatttgt
    26701 aaggagcaat acagtatgaa aaaacaatat gtgtttataa tactagcaag tactatttta
    26761 ggtatacttg ttggaaccat atttagagat tataacaatg aagaaacagt ttatacaagc
    26821 aaagacaagt caataagaaa agaaataaaa atgacaagaa aatctataaa agaattaacc
    26881 aaagagaaag acaagttaga taaagaaatt aattcaatga aacaaaatca aaaaaattct
    26941 gaagaaatat cagaaataga aacacttaga gatagtctat catattcaga tgtaaagggt
    27001 agtgggataa tattaagtat agatgctata gatgaaaaaa cagggaatat agctaatagt
    27061 atagactata ataagattct tgtaaaagtt ataaatgaat taaaagtaaa cggaggaaaa
    27121 tacatagaaa taaatggtca aagaattaat caatattcag aagttgtact tgcaggaagc
    27181 catataaata taaatggagt tcctgtagca caaccatatg aaataaagtg cattggagat
    27241 aaggagaaac tatctaatta tgtagataaa ggtagtaaat atttagatag catacaaacc
    27301 aattatccaa tgaaaataag cataaaaact gaagaaaata tctctatgaa aaaaatgaat
    27361 atacctaata aattaaagta tataaagggt gattaagatt atattagagg aaagcagttt
    27421 gccaatgtta ataccagaaa aacttgcaaa aaaatataat gtatttccag ttgagtttca
    27481 agatgataat ttagttgtag aaatagaaga tgaggatatt tatgctctac aggacttgag
    27541 attagctaca ggtaaagaaa ttatattgaa gaaggagaaa aaagaactta taagtgaaaa
    27601 gattgaaaaa tattataata gctttgaact tgatgaggat tatgcaaaaa aattatttga
    27661 aaatctttta gaaaaagcta taaaagaaaa cgcaagtgat atacatatag aaccatttaa
    27721 agaacattta atagtgagaa tgagggtaga tggagaacta aaggaagtat caaaattttt
    27781 agttgatgtc tatccatcat tgtctacggt tataaaatta aaggcatcaa tggatataac
    27841 agaaaaaagg cttcctcagg atggtagggt ggatataaag ttaggtggaa atttaattga
    27901 cattagagtt tcatcaatac caactgtcta tggtgaaaaa atagttttga ggatacttaa
    27961 tagagatact tttttaaaag acaaattaga acttggtttt tcagaggaag ctataaaatc
    28021 tataaatcgt ataataaata aaagagcagg aatattatta gtgacaggtc ctacaggtag
    28081 tggaaagact acaacagtat attccttatt aaatgattta aaaggaataa ataaaaatat
    28141 tatgactata gaaaatcctg tagagtataa gatggatggc ataagtcaga ttcaagtaaa
    28201 ttcaaaagta gggttgagct ttgatgtagg tcttagagcg atattaagac aagacccaga
    28261 tataataatg gtcggagaaa taagagatgc agaaacagct aagatagcag taagagcagc
    28321 tataacaggt catttagtta taagtacttt acatactaat gatgcagtat cttccatagc
    28381 tagattacta gaaatgcaaa taccaccata tcttttaaat gcctctctta taggtgttat
    28441 atctcaaaag ttggttagaa aagtctgcaa tcattgtagc catgagatta tgataaaaga
    28501 taattttagt ggagatgtaa atactaaggt agctgtaggg tgtgaaaaat gtaatgataa
    28561 aggatacttt ggaagaacag caatttatga aatcttagaa attaatgatg atataaagac
    28621 atgtataaga aatatggagg attctagtac tattaaagat gtggcacaaa ataatggaat
    28681 gataacattt gaagatagtt gtaaaagact aataaatgaa aaaataacga cattagaaga
    28741 gtgtttagta gtaaatgaaa tgatttaact gaattgtata gttaaacttc gtttggtcag
    28801 ttgtctttat ttaatctatt ttaattaaga tgtttgagta taaattatat ttaagtgaaa
    28861 taaaattaaa tgcattaaat tagaaaatat taagtttatt taattgtaat taatataatt
    28921 tggaaggtat tatagtacat gagattatct aaaaatatat tttataattt agaaaagttt
    28981 tatttagtat taaatagaat cagtgataaa gaaattagag taatttgcaa agagataggc
    29041 atattgctgg aatctggatg tgaaattaca aaaatatttg aaatcattga gagtcagtca
    29101 agtaaaaaag taaagaattt gcttagtata gtatcaaatc atattcaaaa aggtaactca
    29161 atagcagaat catttcaaat aacaggtata ttttctaaat tctttataag tatgataaaa
    29221 gcaggagaaa ctagtggaaa cttagatata ataatgagtg atttatctaa ttattatgat
    29281 aaagaataca aattaaaaat gaaaataata actatttcaa tatatccaat aatacttata
    29341 atattatcta tcttatcaat gttgtttata ttcgtatttg taatacctaa ttttcaggtg
    29401 gtttttacca acaatggaat tgaaccacct ttaataacta gagttttaat gggaatatct
    29461 atagtggtta caaataactt agcttatata atatttagtt ttatattgtt ttcaatagga
    29521 aacatttatt tctttataac aaatgataat ataaaaaaat tgattaattc gttaaaattc
    29581 aaaatacctt ttataaaaaa aattaatcag ttagtagcta caacaagatt ttcaagggca
    29641 ttgtccgttt taattagcag tggaatacaa attgtggaag ctatagacat gtcagctagt
    29701 gttgtagaca acgaatttat ttatgaaagg ttaaagattt ccaataatta tataaaaaaa
    29761 ggaaatagca taggtaaatc tttgaattta gcaaatattt ttccaaaatt atttatttca
    29821 atggcaaata caggagaaga aagtgggaaa ctagataaaa gtctaaatgt aataaataaa
    29881 ttttatgaaa atgaattaaa taacaaaata gagcaaataa tgaaatttat agaacctatg
    29941 ctaattgtat ttatgggatt aattattggt acttttattt tagcaatggt tgttcctatg
    30001 tttgatgcaa ttactaattt ttagagagaa aaataaattt tattagatga aacttttgaa
    30061 aaggagagaa tatttaattg ataaatttga taaataaaaa acgaaaagga tttacacttg
    30121 ttgaaatgat tgtagtagta actattttag gcgttatatc tagtatagca ttagttaagt
    30181 atagtaaggt tcaagaaagt gccaaattaa atgcagacta tacgaatgct gctaatatag
    30241 taaccgcagc tagcatggca attaatgatg atgaaaagac aatagactct ctaagtgtag
    30301 agacattgaa ggaaaaggga tacctaaata ctgttccagt tcctcagagt acatcaggta
    30361 aattcgaact tgtcataaat gatagcggaa cagatataag cgtaaatata aattctaagc
    30421 aattttatcc aaaataatat tttatattga ttgctgtaag ttttaaaatt atttttattt
    30481 aagaaggaga tggctataat taaaaaaatt ctaaacttag aaataaatga tgattatata
    30541 aggcttgtat ttttaagaaa aagtcataaa aaagttttta tagataaatc aattataaaa
    30601 gagattaact ttgatataaa aaatgatagt aattcgattg agaagattaa atatatagaa
    30661 gatgtagtta gatttgtaaa agaggagatt ggtaaatcaa aaatattata taaaaattta
    30721 tactttaaca ttcaaattca ggatatagtc attagaaatg ttgaagttct aaatactaag
    30781 aaaaaaagag acatattaag catgattgaa tttgaaataa cacaatacat tccaataaac
    30841 ataaataact attcaataaa atataaagtt ataaattcta aaaatgataa attgaatata
    30901 caagtaattc ttttcccaaa gagtattatt caattaatta agaacatttc agaaaatcta
    30961 aatatgaatc caaagactat aaatataaat tttgatatat tacaaaagct tataaactta
    31021 aatttaatag agaatttttc agaagaaggg gtatttatag aatgtaaaaa aagtcagtta
    31081 attataaata taacaaaaga taaaaaaata agagaaacat acttgctatc aaaagaggga
    31141 aaatcatatg agttcataaa aagattatta agggatttta agtatgttta ttactatggt
    31201 atagaaaatt gttttattga agaatacttt aaatatacag ataaatctat tgaagtaaat
    31261 ccattaagat taaaagataa agtaaaagta gaaaataatt ttgatgcaga tttagaagac
    31321 aataggataa attatataaa tagtatagga atgattattt aagtgaaagt ggataaaaca
    31381 ataaattttc ttaatggatt taaaaaaact aaaccatgta ataaaatcta taaaataata
    31441 atagtcttaa ttttaacgtg tattttattt aaatcattta tgtatgtgaa atctataaat
    31501 gaacttgaag attatataag tcaaaataag ctagtggata aatcaaagaa cactttacca
    31561 acaacagaca aaactagaga gaaattttct aaaataaaac ttaatgaaat aaaaaaaata
    31621 tatgaaacaa ttggaataaa tagtattact aaaatatcaa tagataaaaa taagctagag
    31681 atggaaggtg tgtgtagtga tttagatgtt ttaaacaatt taaggaaaat aaagtacata
    31741 aaatattatt acatagacag tattgtaaga gatggagaat attatagatt tagaataaaa
    31801 agttagatgg gtgattattt ttgagattaa ataatagaga aaaaaatcta cttaaaatat
    31861 tgttaatatt agttattata ttggcaagtg atatagcagt aagttatttg gaagaaaacc
    31921 taactagttt gaagaatgaa aagcaaaata taataaataa aataaataat caagataatt
    31981 atcaaataaa ggataataag catatagatg ataaatatat agaaagtgtt gaatcaaata
    32041 aaaatgaaga attaaaaaat aattttaata actcattttt agataaaaaa acaaataaag
    32101 atatagtgtt attagtagaa aatgaactga gagatattgt gaatgtagaa tatattaatc
    32161 aagaaagtag tttagataat cacaataaaa aacaagttaa tttagaaata aaagttaatg
    32221 gagaacttgc aaatgtgttg aaacttgaag gtgtaatgaa gaagttaaga ctaaataata
    32281 aacttgaaaa gatagaaatt aataaattaa aagtcaataa ttttgatgtt caaaatattc
    32341 caaatgaata taaacaagaa aaagacaata ttgttgaatg taaaatgaca gttagagtca
    32401 tataacaaaa aagaatagat aaagtaaaaa actattatca attaataaaa ttttatagag
    32461 gaattagttt tacgataatt catttctaca agagggattg ttgatgattt tatcgaaatc
    32521 ctaattaaag ttaatatatt gtaccaaaat ataagtgaat ttaatagaat atttacttat
    32581 actatagatt gattaataaa aaaatggtat aataacaaat tgtactttaa tttaataata
    32641 agggagtgga agtcatattg ttagggagaa atgagctatg cccttgtgga agtggcaaaa
    32701 aatacaagaa atgttgttta aataaagata ttgtttcaga aagagcatgc agaaaaactg
    32761 aactttcaca aaaacaatat acagatttat attcaaagtt atatgattat tcaagacagg
    32821 ataagtttaa agaagaatgt gaaaaagcta aagaaatgtt ttatataatg caaaatgata
    32881 gtgtaaatga aaaatttgaa agatttttta atacttattt aatacaagac cacataatgg
    32941 aaaataaaaa ggttatgaca gttggttttc ttgaagaaaa tggtgcaaac ctaagtcaat
    33001 cagaagtatc aatattaaaa agtatgtttg aatcatacgt aagtatttat gaggtaaaag
    33061 aagtttctgc tggaaaaata gtattaaagg actgtttaag tggaaatgaa ctttgtacag
    33121 aagatgtaaa acttctgaga agttttaaaa tcggaagttg tatgatagct agaatagttg
    33181 atattgaagg aactaacata ttgatagata taactataag tatatcaaat gaggttaaag
    33241 atataatttt aaaggatatt atgaatctat tcaatcaata tcaagatgta tacaaagata
    33301 tgaagtcgtt cttaatttat catacacata tactatacaa gtatatacaa cagcttttag
    33361 acccaagtat agctgaatat ttaaagagag aaagagataa aaacgataca aaagttaatt
    33421 cagaaaatga attagctgaa gaagaatgta aagttctaga tactcttaaa gaaaatgtag
    33481 aaaaagaaaa tatagatgca tgtatagagt tttggaatga atataagaaa aatcatgaaa
    33541 atataaaagg agctgaaaat ggttgggcag ctgctgttga atactatgtt aaaaaagaag
    33601 caggacaacc tataactcaa gttcaaatat caaagaaata cgatataagc tctagtacac
    33661 taggaaagag atacaaggat ttaaaaatat cttaattaat tataaaaagc tttaagtcat
    33721 agataaagaa tctatagtat aatatatgta taatgtttag aaagaggtat taataatgag
    33781 tcttagttta ggaaatgcaa ttgctgtatc aacgaacttt ataaaatcta acccagctgt
    33841 acctgtgtac aacggagaag aaatatatgc agttatttat catatagaaa taggatataa
    33901 taatggtgta tcacctgata ccaaacaata tataataata gactataaag agtttgattt
    33961 atctatggat aaaaaaaatg aactaataaa tattgctaaa gagtactgta aatctaaagg
    34021 tattgtagaa aacgaaaacc ttgaaataaa ccttttagac aatgaagaag cagagaactt
    34081 cttagaaaag gtgtttaata atatgaaggt tataagaggt cttataacta aaaaaggata
    34141 aataaatgga ctatatagga atagaaaata taacacctta tgaaaataca tatgaattta
    34201 gtgtatatga atatgatgat gaaatcacct taggtagtga aaagttatat gtatgtgaat
    34261 taagggttgt attgattaaa gttaattctc tgtatgttga aagattgcat aaatcagttg
    34321 aagcaatggt cttagtaaaa aacttgaaaa aagatttaga taaaacactt gttgtaaaca
    34381 aaataaagaa ttttgtgcta gatgagattt gggtagaaaa tctagtaaaa gagaatatag
    34441 aagttatatt tgtagaaagc taggaataac cctagctttt ttatattaca atctaagaga
    34501 ggaaaacaat atgttaagag tatctaatgt aaaacttgga attgataaag atatatcttt
    34561 attaaaagat gttatactta agaagctaaa aataaaagaa aaaaacttag tcaaatatag
    34621 tatatataaa gaatctatag atgctagaaa aaaaggaaaa atggaatttg tttattctgt
    34681 agatgtagaa gttaaagatg aaaataaaat acttaactca aaaataaaag atgtaacaaa
    34741 aataaaggaa atcagatacg taaatgtacc tgtgggtgat aaaaaattaa agaataatcc
    34801 tttggtaatt ggtagtggac cagctggctt gtttgcaggt ctgcttttag ctcaaatggg
    34861 ttatgaacca atcatacttg aaagaggtct tgatgtagac agtagaacca aagatataag
    34921 tgatttttgg acaactagaa aattaaaaaa taattcaaac gttcaatttg gagaaggtgg
    34981 agcaggaact ttttcggatg gtaaacttac aactagaata aaagatatac gatgtagaaa
    35041 agtattagaa gagttagttc agtttggagc accagatgaa atattatact cacataagcc
    35101 acatgttgga acagatatat taaaaaatgt agttaaaaat ataagaaatg aaataataag
    35161 tttaggtggt caagttagat ttaattcaaa agtaacagat atagttgtat caaatgattc
    35221 tatacaatct gtaataataa atgatactga aaaaatagat acagatacaa ttatattagc
    35281 tgttggacat agtgcaagag atacttatga aatgttgtat tcaagaggta taaaaatagt
    35341 tcaaaaacct tttgcaatag gagctagagt tgaacatcca caagatttaa taaataaagc
    35401 acagtacaag gatttttata atcatcctag gttaggagct gcagattata gacttataga
    35461 gcatgtttca aatggaagaa cagcatatac tttttgtatg tgtccaggag gtagtgtcat
    35521 agcatctgca tcaaatgatt ttgaaatagt tacaaatggt atgagtgaac atgcaagaga
    35581 taaaataaat gcaaatagtg catttttagt aaatgtaacg ccagaagatt ttaagagtga
    35641 taatccacta gcaggtgttc atttccagca gaagtatgaa aaattagctt ttgaattagg
    35701 tggaaaaaat tataatgcac cagttcagct tgttggagat tttataaata ataagacttc
    35761 tttgaattta ggaagtgttg agccatcata tagaccagga tatacactta caaatttaag
    35821 tgaatgtttg cctagcttcg taacagagac tatgagagaa gcgtttatat ctcttgataa
    35881 aaaattgaat gggtttgcaa tgtatgatgc tgttttgacg ggagtagaaa ctaggtcatc
    35941 atcaccaata agaatagtaa gagatgaaaa tactttagaa tcagtgagta ttaagaatct
    36001 atatccatgt ggtgaaggtg ctggatatgc aggtggtata gttacagcag cagttgatgg
    36061 tataaaatgt gcagaaaaaa taatacaaaa atacaccaat aatacaaaaa tttaacataa
    36121 acttaatgat tttttaatat ttaacatgaa tttaacatta tcactcctat aatttgataa
    36181 aatacaatag gttataaaat ttttagatac agtaatctct ttacaaggag gaaataattt
    36241 gaacattata ataagtctaa tgggtggatt aggtctgttc ttatatggta tgaaccttat
    36301 gggagaaggt cttcaaaaat ctgctgggac aaagctaaaa aagataataa aactacttac
    36361 tagtaaccta tttatgggag ttttggtagg tacaggagtt acagcagtaa tacaaagttc
    36421 aagtgctact actgtaatgg ttgttggttt cgtaaatgca ggaataatga ctttaaaaca
    36481 ggcaatagga gttataatgg gtgctaatat agggactact gttacagccc aattggtatc
    36541 tttcgactta actggtatgg ccccagtagc attaggtgta ggtattatac tttatttatt
    36601 tggaaataag cctagaataa aaaatatagc cgaaatactt ataggttttg gtatattatt
    36661 tacaggtatg gattttatga agatggcagt ggagccacta agagactatc aaggatttac
    36721 tgacttactt gttacatttg gtagatatcc actacttgga ttattattgg gatttgggat
    36781 tacagcaata atacaaagtt caagtgcatc tatgggtatg ttggttgcac tggcagcaga
    36841 aggtctagtg ccactatcag cagcactgcc aattctttat ggccaaaata ttggtacatg
    36901 tgtaacttca ctgttatcaa gtattggtgc taacaaaaat gcacgaagag cagctatgat
    36961 gcatctaatc ttcaatgttt taggaacagt gatattctta atattcttga ataaaccagt
    37021 agtaagcatg gttacaagtt gggacccaag caatgttgca agacaaatag ctaatacaca
    37081 tacattgttt aatataatat ctgtattgat acttttacca tttacaaatc ttattataaa
    37141 actagctata aagcttgttc ctgatagagc aggtgatata gatgaagatg aaactaaaac
    37201 tattaaatat atagatgata gaatgataga aactccttct atagctcttg caaatacgat
    37261 aaaagaagca cttcgtatgg gtgagaaggc gaaggaaagc ctaaatgcat ctatggaagc
    37321 tttagtagaa cattcaactg aaaaaataga taagacatat aggcgagaga gattaatcaa
    37381 tgatttacag aaagctattt taaattattt acttaaactt tcaaaagcac ctttagatga
    37441 tgattcaaga gaagttgtgg atactttgtt taatacagtc aatgatatag aaagaattgg
    37501 tgaccacgct aaaaatatag ctgaattatc gcaagttgca atagattcaa atatttcttt
    37561 ctcagaagaa ggacaatctg aacttgatgt tatgtataat agagttgttt cagcatatac
    37621 ttatgcatta gaatcaatga gaactgataa tgttgattta gcttgtaagg ttataaaaat
    37681 tgaagaacaa gttgatataa tggagaaatc ttgtagagct aatcacatgt atagattgaa
    37741 caataatcta tgtagtatag aaaatggagt tatttattta gacgtaataa gtaatttaga
    37801 gagaatatct gaccatgctg tcaatatagc acaacaagtt atagcaaaga gattaggaaa
    37861 tgattaaaaa taattaattt aaaataatat aaaatttaaa atagaggata aataaaagag
    37921 aaactttaaa tgatacgttt agagtttctt tttttgtaaa tttatttgac taaaattttt
    37981 aaatttatac atagttatag catttagaag aatcgatttc ctgataataa atgatgagat
    38041 atgtatgatt ttgtggcaaa cttttaaaaa aaacacctat attttgtgtt ataatctctt
    38101 taaaacgaat atgctgaaaa gagggattta aatgggaaaa ataaattttg attatagtaa
    38161 agctacagag tttttttgtc aaaacgaaat agatgtcatg caaccatatg tagatgttgc
    38221 gcacgacatg ttacataata aaactggttt aggaaatact tttttaggat ggatagacct
    38281 tcctaaaaat tatgataaag aagagtttga cagaataaaa aaatctgctg ataagataaa
    38341 atcagactca gatgttcttt tggtaatagg tataggaggc tcttatttag gttcgagagc
    38401 tgctatagat atggtaagtc attcttttag gaatggactt aaaaaagagc aaagaaaggc
    38461 tccagaagta tattttgtag ggcataatat aagctcaaca tatattatgg atttattaga
    38521 tataattgaa ggaaaggata tttctgtaaa tgtaatatct aaatcaggaa ctactacaga
    38581 accagctctg gcttttagaa tatttaaaga ttacttagag aaaaagtatg gtaaggaaga
    38641 agcaagaaag agaatttatg caacaacaga tgcaagtaaa ggtgcactta gacagttagc
    38701 tacagaagaa ggatatgaga cttttgtaat accagatgat gtaggtggtc gtttttctgt
    38761 attgacagca gttgggttac ttcctattgc tgctgctgga cttgatattg atgctatgat
    38821 gaaaggcgca aatgatgcta gagaagcatt tcaaaatcct gacttaaaaa gtaatgatag
    38881 ttatagatat gctgttgcta gaacaatttt acatagaaaa ggaaaagatg tagagttatt
    38941 agtgaactat gaacctcaac tacattatgt aagtgagtgg tggaaacagc tttatggaga
    39001 aagtgaagga aaagaaaata aaggtttatt ccctgcttct gtagatttct caacagattt
    39061 acattctatg ggtcaataca tacaagatgg aaaaaggctt ttatttgaga cagtacttaa
    39121 tgttgaaaac tgtaagagaa atataactat aagttcagag gaagtagact tagatggttt
    39181 aaattattta gcaggcaaga ctgtagattt tgtaaatcat aaagcttttg aaggaactct
    39241 attggctcat acagatggaa aagtacctaa tttagtaata aatatacctc aactagatga
    39301 gtataatttt ggatatttag tttatttctt tgagaaggct tgtggaataa gtggatattt
    39361 attgggagtt aatccatttg accaaccagg agtagaagct tacaagaaaa atatgtttgc
    39421 tttactaggc aaaccaggtt atgaaaaaga aaaggaagag ctagaaaaaa gacttaaata
    39481 attttaaata gttaaggttt aattaagatt aaaataatat aatgaaatca tcgaaaagga
    39541 gtttactcaa aatagatgat ttcatttttt ttatgaaaaa ttgggaaaaa tatattttga
    39601 taatttatat tatattaaga tagggagtgg tatgagatgt caagaagaaa gaaagggata
    39661 agtttagtaa tattagttgc tataataagt tcaatactta gtagttttct aacaataatt
    39721 ttagttaagg acaatttagt aagtaaatct acaggaagtt ctacgccgat agttgtaaat
    39781 gatgatggta agagtcaaaa tatttatcaa gcagttgcag aaaaagctac gccatctgtt
    39841 gtaggtatta caacaactag tgttgatact agtaatatgt ttgcaatacc aactgaaaca
    39901 caaggtgtag gaactggaat catagttgat tcaaatggat atatacttac taattctcat
    39961 gttatatcag atggtcaagc tacaagtgta aatgtattat tcaatgatgg ttcaacaact
    40021 tcaggtaaag tagtatggtt tgaccaacaa cttgatttag ctatagttaa ggttgataaa
    40081 actggactaa caccagcaga atttgctgat agtgacaaag taaaagttgg agatatatca
    40141 atagcaatag gtaatcctct tggattagat tttcaaaaaa cagttactca agggataata
    40201 agtggattag atagaactat acaaacagaa aaaactaata tgactggttt attacaaact
    40261 gatgcaagta taaatgcagg aaatagtgga ggaccattgt taaatcaaaa aggtcaagta
    40321 attggtataa acacagcaaa agcttctcaa gcagaaggat taggatttgc aataccaatc
    40381 aatacagcta agagtatagt tgaagaagta atcaaaaatg gaaaatatga aaaagtaact
    40441 ttaggcataa aaggtacaga tgtatcaaat tatgaagcag caacaggtac aaaattaagt
    40501 actgataaag gtgtttatgt tgcagaagta atatctggtt catcagcaga aaaagctgga
    40561 gtaaaggtag gggatattat aactaaagta ggagatacag atataacagg tatgaatgat
    40621 ttaaataaaa agttgtatac tttctcaaaa ggtgctagta caaaaataac agtaaataga
    40681 ggcggaaaag cagtaacaat aaatgtgaat ttctaaatat gaccagaaag atagagacta
    40741 catggtaaag tgtagtctct atttttattt aatttttata gtatatacat ctaaattaat
    40801 taaaatgatg tattgtttat agtttattgc tatattttct tataaaaata aatttaataa
    40861 atatttaaat ttaatttaca aaaacaatat aaatatcata ataaaataaa attttttaat
    40921 attactaaaa atatatagac aaaataataa caaatatagt attatgtaat tgtagaaatg
    40981 cttttcatag gtatattcta tgaagatgaa ttgcataaaa atgaaaaaat ggaatggata
    41041 ttatttaggg gtgaaaaatc atgaatccat tagttataaa cttacaaaaa tgtagcatac
    41101 atgatggacc agggataaga agtacagtat tttttaaagg gtgtccactt gaatgtgttt
    41161 ggtgtcataa tccagagagt caaacatata caaaacaagt tttgtataat gaagaaagat
    41221 gttcaaaatg tgaagcatgt ataaatatat gccctcataa ggcaatttac aaaggtgaaa
    41281 caaaaatatg cttagaccaa gataagtgtg agttttgtga aacttgctta gactattgtg
    41341 taaacaatgc aagagagatt gttggtcaag agtattctgt aagagatttg gttaaagaga
    41401 tagagaagga tagaattttc tatgaagaat caggtggtgg agtaactcta tcaggtggag
    41461 aagtaatggc tcaagatatg gacttcattt gtggagtaat aaacatgtgc aaatcaaagg
    41521 gaatccatgt agcaattgat acatgtggct atgcaaagtc agaaaattat gaaagagttg
    41581 ctaaatgtgc agatttgttt ttatatgata ttaagcttat tgatgaagat aagcacataa
    41641 aatttacagg aaaatcaaat gacttaatac tgaaaaatgt taagatttta agtgaattag
    41701 gggctaacat aaatataaga ataccattaa ttgtaggagt aaatgtagat gatgaaaatt
    41761 tagaggttaa aaaaatgata gagtttttaa agcctttgaa tatacaagca gtaagtcttc
    41821 ttccatatca taatattggt aaacacaagt atgataaaat ttataaaaag tatgaaggag
    41881 aagaactaca aagaccatca gaagaaaaat tagaggaaat aaaaagactg tttgaagcaa
    41941 gtaatttcaa tactaagatt ggagggtaat aaaatgtcaa gaggaacttt tgagagaact
    42001 aaaaaattaa gagaagaaag tattaatgca gaaccacaca tatctattga aagagcagta
    42061 cttatgacag aagcttataa aaaatatgag ggaagtgtag agattcctgt acttcgtgct
    42121 ttatcattta agcattatat tgagaataga actcttagca taaatgatgg agaattaata
    42181 gtaggtgaaa aaggtgattc tcctaatgga gcaccaacat atccagaaat ttgttgtcat
    42241 acaatggaag atttagaagt aatgcacaat agagatataa taaattttag cgtatcagaa
    42301 gaagctagaa aaatacataa agaagaaata attccttttt ggaaaaagag acaaacaaga
    42361 gataagataa taaatgcaat gacacctgag tggttagcag catatgaagc aggtatgttt
    42421 acagagttta tggaacaaag agctccagga catacagttt gtggagatac aatatataaa
    42481 aaaggatttt tagatttaaa gaaagacata gaagcaagat taaaagagct agattttctt
    42541 aatgatttag atgcatataa taaaaaagca gatttagaag ctatggcaat agcttgtgat
    42601 gcaatggtta tattaggtaa aagatatgct gagaaagcaa gacaaatggc agaagaagaa
    42661 acagatgaag ctaagaaaaa agatttatta ctaattgctg aaacttgtga tgttgtacca
    42721 gctcacaaac cagaaactta tcatcaagct atacaaatgt attggtttgt tcatataggg
    42781 gttactactg aacttaatat atgggatgct tttactccag gaagacttga ccaacatcta
    42841 aatcctttct atgaaagaga tgtagaaaat ggaatactag atagagatag agcacaagaa
    42901 ttacttgaat gtttatgggt taaatttaac aatcagccag caccaccaaa agttggtata
    42961 acattaaaag aaagtagcac atatacagat tttgcaaata taaacactgg tggaataaat
    43021 ccagatggtc aagatggtgt taatgaagtt agttatataa tacttgatgt tatggatgaa
    43081 atgaaattga tacaacctag ttcaaatgtt caaataagta aaaagactcc tcaaaaattc
    43141 ttaaagagag cttgtgaaat atcaagaaaa ggatggggtc aaccagcatt ttataatact
    43201 gaagcaatag ttcaagagct tatggaagct ggaaaaacta tagaagatgc aagacttggc
    43261 ggaaccagtg gttgtgttga aactggatgt tttggtaaag aagcatatgt tctaactgga
    43321 tatatgaaca ttccaaaaat acttgaatta acattaaata atggatatga cccaattagt
    43381 aaaaaacaaa taggtattga aactggagac cctagaaatt tccaatctta tgaggaacta
    43441 tttgaagcat ttaaaaagca attacattat atgattgaca taaaaataga aggaaatgct
    43501 gtgatagaaa atatatgtgc aaaacacatg ccttgtccac ttatgtctac aatagttgat
    43561 gattgtatag aaaaaggcaa ggattaccaa agaggtggag caagatacaa cactagatat
    43621 atacaaggtg ttggtatagg aactataaca gatagtttaa cagcaataaa atataatgta
    43681 tttgataaga aaaaattcga tatggataca ttgcttaaag cacttgatgc taattttgaa
    43741 ggatatgaag ctatacttaa tttagtttca aataagactc ctaaatatgg aaatgatgat
    43801 gattatgctg atgaaataat gcaagagata ttcaatgcat attacaatga ggtaactggt
    43861 agaccaactg tttgtggtgg agaatacaga gtagatatgt taccaacaac ttgtcatata
    43921 tactttggag aaattatggg agcaagtcca aatggtagac tttgtgcaaa accagtttca
    43981 gagggaattt cacctgaaaa aggtggagat actaatggac ctacagcagt tataaaatct
    44041 tgtgctaaga tggaccacat aaaaactggt ggaacattat taaatcaaag atttgcacca
    44101 tcagtagttc aaggagaaaa agggttagat aatatggcta atctagtaag agcatacttt
    44161 aatatggatg gtcatcatat acaatttaat gtatttgata aaaatgtact gttagaggct
    44221 caaaagaatc ctcaggatta taaagactta atagttagag ttgcaggata tagtgaccat
    44281 ttcaataatt taagtagaac actacaagat gagataatag gaagaactga gcaaacattc
    44341 taggtttgct tgtaaataaa acttcttact atataaaatc gtaactgata taataaagta
    44401 taaatggttt gattccattt ttaaaatttt agattaatta tgagctaact ttctaaatag
    44461 gaagttagct cgttaagttt aatgaaaaaa tcgttaaatt tatatttagt aaatcataca
    44521 catattagta agtaatacat acaaaagaat aatttattat agttataata aggttatatt
    44581 ttataaaaat aagataattt taagcagtta aaataaagtc aatttagcta ctttaaaata
    44641 aaactaatag aaaaaaggag atttgatatg aaaactttag gatttattgg ttcagggaat
    44701 atgggaagtg caatgatagg tggcatagta cagtcaggat tagtaaaggc agaagatata
    44761 actgtatcag atttaagcca agttgcctta gataaagtaa aagaagaatt tggagtaaat
    44821 actacaactg attcaaaggt agctgttaca aattctgatg tggtaatagt agcacttaaa
    44881 cctaatatat gcgaaaaggc tttaactcca cttaaagaat taatagatgc aaataaaata
    44941 atagtatcta tagcagcagg taaaactata gaaagtctgg aaagttttat aggttcagat
    45001 aaaaaaatag taagagtaat gcctaatact ccagcccttg ttggcgaagg aatgtcagct
    45061 ctttgtaaaa atagtaatgt aacagatgaa gagttaaata tgattaaggc tctgtttgaa
    45121 tcttttggtg aggcagaaat agtatcagaa tatttaatgg atacagttac aggtattagt
    45181 ggttcttctc ctgcatatgt atttatgttt atagaagcta tggcagatgc agcagtatta
    45241 gctggaatgc caagacaaca agcttataaa tttgcatctc aagcagtaat ggggtcagct
    45301 aagatggttc ttgaaactgg aaaacatcca ggtgaattaa aagatatggt ttgttctcca
    45361 gcaggaacta ctatagaagc tgttaaggta ttagaagaag aaggctttag agcagcagtt
    45421 ataaaatcta ttgttgcttg tatagataag tctaaagata tgagcaaata acagatgtaa
    45481 ttaagtttac tatatggttt cttgaattgt ttttttagtg cttatttata tctatacata
    45541 aatgtatttg gtataagtaa aataagagta atttactata aaaaggaatt taatgattga
    45601 gtgagaattt attacttaaa tattaataat taaatagata tatttttaac tatatttgag
    45661 atatatcatt gtgaaaaaat aaaatttata agtattattg tgaggttata agtagattta
    45721 tttaaaaata aatttattta tagccttttt aaatttgaaa taatattcat aaggtaataa
    45781 aagttacaaa tattttcttc gctaataagt tttaaaatac ctataatgtt ttacttttta
    45841 ttataataaa tacaataaat atattcttat ataaattcta tgtcagatat atggaaagat
    45901 aagaaccttg agattatgtt aaaaaatcta gattttatac ttataaaaag tttgatttta
    45961 caaccttaca aaagagaatc aagataggaa tataattatc tttttcataa atatataaat
    46021 gatatactaa tattatagta ttattgatat ttgtattgga ggttgaacat gagggatgaa
    46081 attttaagtt ttgtaaatga atgtgtatta tttaacaact ttgatgaact taaaaaagaa
    46141 agtggcataa taacagaaga tatagtaaaa aagtttaatt taagtagaac tcaatcaagt
    46201 agattattaa atgatttagt aaaatctgat aatcttataa agataaacag tagacctgtt
    46261 atttttttac ctaaaaataa aataaatgat gtagtaggac ctacaaaaaa aagtatttat
    46321 gaaaatttag atgaacttaa aaatgagtgt aaattattaa agcaagagac tgtgtttaat
    46381 agtatcatag gatatgagaa tagcttaaaa gaagtaatcg aacaaataaa aaccgctgta
    46441 ctttatccaa atggcggact tacaataatg ctgacaggtg aaagtggagt aggaaaaact
    46501 tttttagcca agataatata caaatatagt gtaagcagta atgtattaga aaaaaattct
    46561 ccatacaatg tgttaaactg tgcgcagtat tataataatt tggagttatt gtctagtcta
    46621 ttatttgggc atgtaaaagg agcatatact ggagcaaatg aatctagagc aggtctaata
    46681 gaacaatcag atggtggtgt tttattttta gatgaagtac atagattaaa tagtgaaggt
    46741 caggaaaagt tatttacatt tatggataca ggtacgtttt ctaggattgg agagaatgga
    46801 gtaattagaa aagctagggt aagattaata tttgctacaa cagaaagtct atctgaattt
    46861 ttacaaacct ttttaagaag aatacccata aatatttatg ttcccaatat agaagaaaga
    46921 gggactattg aaaaaagaaa gattgtagaa cattttattt atgaagaaag taaggtactt
    46981 ggtttgccta tagagataac tcaaattaca ttaaatgcga ttttaaagat aaaattcaag
    47041 gggaatatag gtgaatgtaa aaatgtaata aaatatgcat gtggacgagc ttatgcaaaa
    47101 aatcaaagaa gaaatggaaa tatttttgtt actcttcaag accttcctag aaatctttat
    47161 atagaaaatg tagatatatt tcaattccaa agtggtaaaa gcaaaagcat tatcttttct
    47221 cctaaacaat ttagtattga aatgtcaaat ggaagaaata aaagaaatat aatctatcaa
    47281 agtttcataa aatgtttaga ttactttgat agactagaaa aaaatgaaat aacaaaggaa
    47341 aaatttagta aaaagagttc taatctaatg attagactaa tggacaattt agtcttttca
    47401 aataatgatg aaaataataa cgtacttatg gagcttataa tatcgataat gcaggatata
    47461 tttagaaatt tagaagttaa taacaatata aaatatgatg ggaataatgt attggcattt
    47521 tcgtcttatc tttatttgaa ggacgaatct tatcaattgt ctgatgagta taaagcttta
    47581 gaaaataaat tactaatata tttaaaaaaa gagagttaca aagaatactc tataataagt
    47641 aaaatatcaa cattaataac gaatagattg gatatgtatc ttaataatgt agatacaatc
    47701 ataatgatta tatttattaa atcaacaatt ataagaatga aatttaatca agttaatgcg
    47761 actattatag cacatggata tgctactgcc agtagtatgg cgaatgtatg taatcggatg
    47821 ttgggtaaaa atatatttac agctattgat atgcctatag atgctactat tgctgatgta
    47881 tcaaaacaaa tgtctagata cctagaggga gataggataa agaatggttt aattgtgtta
    47941 tttgatatgg gctctcttaa tcttatatat gaagatttaa agaataagat aaatagccca
    48001 atgttattta tagaccaaat atccactatt tctgcactag aagtaggaaa tttattaatg
    48061 caaggtaaaa acattgaaga gattgcagaa attatggatg aagaaactaa acctaatata
    48121 caattgtatt atcctcaaaa aaataaagaa tatgctataa tatcatcttg ttttacaggg
    48181 ataggtactg ctataaaaat ccaacatcta ctttccgaaa gtttaattgg aatagttgat
    48241 gtcaaaataa taccttatga ttatgatagt cttgtttcta tgggagataa agaaccagtt
    48301 tttgaaatgt atgatgtgat ggctatagta ggaactgcca atccaaatgt gaatggggta
    48361 gattttatat tattagagga tataatatca ggaaaaggag aagatgatgt ttttagaata
    48421 tttagcagag tagtagaaaa tgaaaaaata aagaacataa atgattctat tgtaaagaat
    48481 ttttcattaa ttagagtaat agatagtcta actattttag attcaaaaaa gataatagag
    48541 agaatagaag aaggaattaa tgctatagaa aatattcaaa agaaaaaact ttcaaatgat
    48601 aaaaagattt ctttatatgt tcacttaagt tgtatgattg aaagattagt tagacaaact
    48661 gaaattgaag agtatactga tatggatttg ttaatcaaaa accatcatag tgaagtaaaa
    48721 ctaataaaaa atgcatttag tgtgctagaa aagagttata gtgtgcaaat accaatttca
    48781 gagataggat atatttataa tattatctat ggtctaccac agtaaaatac aagattacaa
    48841 aataagtgaa tgaaatttaa aaaagtatgc cagtatttgg catacttttt gcttttatag
    48901 ataaatgaga gtataaacaa taaaaatttt aatgtatgat ggaggatttg gggaaaatgg
    48961 tatctttgat gagaattgat gacagattga tacatggtca ggttgcatat ggatgggcaa
    49021 catcactagg tataaatgta atactagttg caaatgatga agcaaaaaat gaccaaatga
    49081 aagctatgtc actgaactta gcgaaaccta gcaatgtaac tttatatata aggggggtag
    49141 aggaatctgg agaaatagta gaaaaatttg cttcttcaaa gaaaagcaat gtattagtgt
    49201 tagtaaaaaa taccaaagat gctttagttg tagctaaaaa ttcaggagga gtattaaaag
    49261 aaataaatgt aggaggatta agatatgagg aagggaagaa gaaacttaca gatttagttg
    49321 ctgttgatga tgatgatata aataacttta aacaaatagg tgatttaggg attgatatag
    49381 aatttagaat gttacctaga gacaaaaaga aacaactatc agatttaata aaataattta
    49441 ggagaaagag aatgaaaaaa tttctaattg caacacatgg agaattgtcc agagagcttg
    49501 ttgacacaag taaattaata attggttcat taactaatat tgagtatttt tgtatgacaa
    49561 cggataaatc agcagatgat gctgagaaag aaattagaag tatattatca aataataaag
    49621 atagtgaaga atttgttgtc ttaacagatg tttttggtgg aagtgtggca aacatatgta
    49681 caaacttact tttacaaggg ttcaaatttg aattattgac aggagtaaat ttaccaatgc
    49741 ttttatctat acttttatta gttgaggagg atacaaaact aatagttaaa tcaggattag
    49801 aggaagcaaa aaatggaatt gtttatgtaa atgagttatt agaaaatcaa aacaaaatca
    49861 aaaatgtaat gtaatttaat gtaaattaaa ctaagttaaa atggaggttc aatatgttag
    49921 tacaagctac tatgttagct attatagcag gagttggtat actagatggg cgtatatttg
    49981 gtcaatctat gcttgatagg ccaatagtta caggtatgtt agtaggatta gttttaggag
    50041 acataaaatc aggaattatg attggtgcac agcttgaatt aatttggatg ggaattgcag
    50101 gaataggtgc agctactcct ccagatgtag taacaggagg cgtattaggt acagcttttg
    50161 ctatattatc aggtaatggt gcagaagttg ctttagcagt agcagtacca gtagcagtct
    50221 tagcacaatc tcttggagta ttagttagaa taataaattc gtacttttct caaaaggcag
    50281 ttttctatgc taaacaagct gattttaaga aagttaccat aatgatgtgg ttgccagtaa
    50341 tattattctt tttaagtaca tcagttccaa cctttttagc aattatgatt ggtgctgata
    50401 aagttacagc attgataaat gcaataccta aagttatatt agacggactg ggtgttgcag
    50461 gaacattgtt gccagcagta ggttttgcat tgcttatgga tatgttactt tcaaaaaaga
    50521 tgtctgtatt tttctttata gggtttttgt tagcatctta tggtggatta gatataactg
    50581 ctatagcttt atttggagta tgtgtagcat ttgtactaaa cttttatatc aataacaaag
    50641 aaaataatca aaatcctcaa ttagcaatca atactttaac ggaaggagag attgactttg
    50701 aataaattaa caaaaaaaga attaagaagt atgttttggc gttcatttgc tcttcaaggt
    50761 gcatttaatt acgaaagaat gcaaaactta ggttactgtt attcaatgtt acctgcaata
    50821 aagaagctat acaataagaa agaaaatcaa gcaaaagcaa tagaaaggca tttggagatt
    50881 tttaatacaa cgacagtagt agttcctgct atattaggta taacagcagc tatggaagaa
    50941 gagaatgcta ataatccaga atttgatgaa agttcaatta gtgctgttaa aacagctctt
    51001 atgggacctc ttgcaggaat tggtgattca ttattctggg gaacatttag gattatagca
    51061 gcaggagtag gagtatcact tgcaaaagaa ggtaatatct ttggaccact attattctta
    51121 ctattataca atataccagc atttgccctt agaatatttg gacttaagta tggttatcaa
    51181 gtaggggtaa attctcttga aagaatacaa agagagggac ttatggagaa aataatgtct
    51241 atggctacaa ctgttggttt attcgttgta ggaggaatgg ttgcaactat gttgagtata
    51301 actactcctc tgaaattcaa cttaaatggt gcagaagtaa ttttacaaga tatactagat
    51361 aaaataatac ctaatatgtt acctttaacc tttgcatttg taatatacta catgttaaag
    51421 agaaaggtaa gtgtaacaaa attaactata ggcactatag taacaggaat cgctttacat
    51481 gctataggtt tgttatagaa attaattata atttattgaa tatatagata aggaaggtgt
    51541 ataaaatgac aatacaagat tatatgttag aaacaccagt tagaatgaga gaaattatat
    51601 ctaatgcaga tagcttattt aatgaagtta agagaacaaa tctaaaaaag attataataa
    51661 caggttcagg tactagctat cactcaggag tgcaagtgca accatattta caaaatttat
    51721 tagatataga tgttgtgaaa atgtatccat ttatgataac tgaagataca ttcaagtttg
    51781 ataatgaaaa taccctagta gtaggtgtat ctcaaggtgg gagtagttat tctacataca
    51841 acgctatgaa gttagctgaa gataagggct gtaaaatagc atctatggca ggttgtaaga
    51901 atgctttaat agatgagatt tctgattata tattaacagt aaattgtggt gaagaaaaat
    51961 ctggagctaa aacaaaagga tattattgta caaagttaaa cttaatgtta ttaggtcttc
    52021 aaatagctag agaaaaaggt ataatatcta gtgaaaagta caatgaggaa ataaataaga
    52081 tattagacgc aattaataga tttgaagcag tgtataagct ctctaaacaa tggattgaaa
    52141 gaaacaaaga aaagttagtt aattctaaag aaataagaat aataggtcac tctgatatat
    52201 atggagatac attagaagca gcattaaaat tattggaaac aatgagaata cctgtaactg
    52261 ggtatgagtt tgaagagttt atacatggta tatataatgc tataaatagt gattctacta
    52321 tatttatact agatacagga aaagaaccta gagtaactaa gatgattgat gtactttctg
    52381 gttggacgga aaatgtattt gctataggta gagatgttac agaaaatgat aaaaatttaa
    52441 agattgatat cacagataat ccttactatc aaacatttaa ttttatagta cctatacaac
    52501 taatatgtgg ggaaatacct acattaagag gtgtagaccc aagtgttcca aaagatacta
    52561 ggttccacat gaagttaggt agcaagaaac tgaataagta acaaaaaaag aggttgtctc
    52621 aaaatagaga taagcctctt ttttactaga taagctcttt tttactgttg aaatgatgaa
    52681 aatatatttg attttctata aaaaagagtg cctcatgaac taaaaagtta attttgagac
    52741 acccactttt atcttatttt aaactaaaat atttatatat tagtgtgcat tatttttttt
    52801 attgctgtct tccttacttg agcaagaatt agcacttgga catccagaac aaatagaaca
    52861 tccactacag acatttccgt tttttgtaga cttgaattta ttaaacagaa taaagagtgc
    52921 aaggactata attattccac ctatcaaagc ttctattatt gaattaccca taaatagtac
    52981 tccacctata cttttaacta taaaagccat tatccatgct agtataaatt gatatgcaaa
    53041 tgatgtaaac atcattttat tgccatattc ttttttcata gttgcaagtg cagctataca
    53101 tggagtatat aaagcagtaa atatcaagaa tgtatatgca gtaactccat taaatattgt
    53161 tggtaagaca acagttagat taccatatag tatatttaaa gagtttacta cgatttcttt
    53221 tgctccaaga ccacttaaaa tagcaactga agttctccaa tcatcaaaac caagaggttt
    53281 gaatatagga gatataatat gacctagagt agccaagaag cttacattta tatcttctgt
    53341 atatccaaaa acattgaatg aagaaagtcc ccaaattacg actgacattg caaacatgac
    53401 agtaacaact cttatcaaga aaccttttga tttattccaa gtatttttaa taagtgcatc
    53461 tatagtaggg attctatatt ctggtaattc taatataaat ggttcagcct ctgttttaaa
    53521 ggctgtttta tttaagaata atgcaactac aattgccata actataccca ccaaatacag
    53581 tgatgtagtt actaaagcag cattatgtgg aaagaatata gctacaaata gtgcatatat
    53641 aggtagcttt gctccacaag tcataagtgg tgcaataaga gctgtaactc ttctatcttt
    53701 ttcgctttcc aatgttctag ttgccattat agctggagaa gaacatccca tacccataac
    53761 tataggtata aaagctttac cagatagacc aacctttctc ataactttat ccattaaaaa
    53821 tgctgttctt gacatatatc cactatcttc aaacaacgat ataccaaaga ataatgtaaa
    53881 tattaaaggg aagaatggta aagtaccacc aacacctcca attattccat caactataag
    53941 tgatttaaac catgggctag agttagataa catatcacta acaggtgcag aaatataagc
    54001 ctctataaga ctagcaaatc cctcttgtag tggacctccg acccagtcaa aggtaaattt
    54061 aaataagagg aacaatacac caataaatat cggatatgct aatataggat tcaagactat
    54121 attgtctatc ttatcactga tagatttctt ttgtgtatat gtagtttttg tacatcttga
    54181 taaaatggat tctaattttt tatatgtttc tgtttcactt ccaaagtttt tctgatatat
    54241 aaaagctttt tgcgtagctc ccttaatctc ttcttctatc ctatcaacac catttttctt
    54301 ttttgctata attggaacaa caattactcc aagttcttca cttaattttt tggcatctat
    54361 attaactcct ttagattctg caatgtctaa catattaagc aatataacta taggcttgtt
    54421 aaattgcata agttgagttg ttaagtaaag gtttcttgat aaattagaag catcaactac
    54481 atttactatt acatcaacat cttcattttc taaatatgat ttagaaacct tttcttcatt
    54541 tgagaaagta tccattgcat atataccagg taaatcgaca acctttatct cttttccaag
    54601 aaatccttct tttttttcta tagtaacacc aggccagtta cctacatatt gatttgaacc
    54661 tgtaagtaga ttaaaaacag tagttttacc gacatttggg tttcctaata atgctacatt
    54721 aatcacgggt agctcctcct ctattattgt aaagaaatat ttttagcatc agattttcta
    54781 atcgcaaggt caaagcctct aaatctaatt ataattgggt ctccaagtgg ggcaaccttt
    54841 ttaacttcta tttcagtact atttatacat ccaagtgcaa gcaatctttt agataattta
    54901 atatctccat ctatactatt aataaatcct ttttctccta tttttaaatc gtaaacagtc
    54961 attattaaca cctcctaatg aaattcatta tcattaaaat tgtaacaagt atgatacaaa
    55021 aagtcaagat ttatagaggt aattgcacat tgaaataact aatatttatt ctaaatagat
    55081 taaaaatatt ttagtctaaa ttaggtgttt ttatatattt tgtattataa tgtaagatga
    55141 tagataaaat ttggaggagt taacttaatg aaaactagaa aaatgacatt tttaggtctt
    55201 atgatagggt atagtttagc tttatatgta ttagagacat atataccaaa tcctcttata
    55261 gttatatttc caggggcaaa attgggtttg agcaatatta taactttaat ttcattaatg
    55321 ttgttaggtg tcaaagatac tgttataatt gttactatca gggtaatttt gtcatcaata
    55381 tttgcaggcc ctttatcata tctactattt agtataggag gagcttatct gagtctttta
    55441 tttatgtatt tagcgagtaa aataaaagat ttatcactaa tagggataag cattataggt
    55501 gcaatagggc ataatatagg tcaattaata gttgcaagtt taatcataga aaatatactt
    55561 gctatagggt acttaccatt tatgttaatg gcatcattag taactggtat gtttgtaggc
    55621 ttagtatcca ggtatacaat acctaaatta aagcattttt atagtaagtt ttattgacat
    55681 aatattgaca aaatataata ttgtttgata aaatgtatat aaaaatatac aaatttgtaa
    55741 tagtggtgat tattatggcg aacaatgaat tagaagcgtt aaaaaatgag attgaagcag
    55801 ttagggaaga gataaataca tacatagaat atccagaaat atttcaagaa gagttagtag
    55861 aatcaagtaa gaaaatagat atattaataa ataaatacat gtacctaagc aaatagccca
    55921 cagttgtggg tttttttgta tcaaaaatta acagatggct atattttaca tatattaata
    55981 ataatattaa gatataaaat agtatttctg atgtgtaaat tatctgtagg acataagttg
    56041 taattaagtc aggagggttt tatattatga ttgatatagg aagtaaggag atagcaataa
    56101 ggttactatt agcactaata ataggaggaa taataggctt agagagagaa aaaataagac
    56161 agtttgcagg atttaggaca catatactaa ttgcaatagg ttcttgtatt gtttcaataa
    56221 cttcgattca attattcttt gattataatt tgtatacaaa tgctgaccca gcaagaatgc
    56281 ctgctcaagt attatctgga attggttttt taggtgcagg agcaatttta aaaaataaag
    56341 gtggagtaaa agggcttact acagctgctg ggatgtgggc aactgcatgt attggtatag
    56401 cagttggata tggttattat gaattggcaa ttctaggtgg attatttgta atgatagcat
    56461 tatttgtgct taggataatc aatacgtttt tatttagcca agaaaagaat gtgttgatat
    56521 taaaattaag caatttggac tctatacctt ttttatatga taaatttgaa aaaaatcaac
    56581 ttatcgtaag aaatatggaa atagaatgtc gtaatgaaga atactggaag gttaattttt
    56641 ttgtatctta tgctaagaga atacacttac acgacgttat gaaagaaata aatatgatag
    56701 aaggagtaat aaatgtagat tatttggact aaaatatata caatatattt tgtaaagtga
    56761 ataaaatata aaacaaatta aaatagaggt gtatgatatg ggaactgata gaagtacaat
    56821 agaagaaaag tacaaatgga agatagataa gatgtactcc agtaaagagg aaattgaaaa
    56881 agacataagt aaagtaaaaa atcttatcca agaagtaaaa gaatataaag ggaagctttc
    56941 tgagagtaag gagaacttat ataaagtatt aaatatctct gaaaatgcat ctaggattgt
    57001 tcaaaattta tatgtatata ctcatatgaa acaacatgaa gatactagaa ttaatgataa
    57061 tcaaggaaga gccactaaga cagaaatgtt atctactgat ttaggtgtgg ctacttctta
    57121 tatagttcca gaaatactgg cgatagaaga gaataagtta agtgaatact taaaagatga
    57181 gaagctatcc ttttatgcaa aatatataaa ggatatattg agagataaac cacatacttt
    57241 gagtgaacga gaggaagaaa tacttgcagc tacatcagaa ttatcgacaa ttccagaaaa
    57301 tgtatacgat atgttagcat atgcagatat ggaatttcct gagatagaag atgaggaggg
    57361 gaataaggtt aagctttctc attcaaacta ctctttattt ataaaaagta agaatagtag
    57421 agttagaaaa gacgcttttg aaggtgaatt ttcaacatat gagaaatata aaaatacatt
    57481 tgcctcaacg ctttatggtg gaataaaatc agagatattt tacgcaaaaa ctagaaagta
    57541 taattcagca atagaagcgt ctttattttc agatgatgta agtttagatg tttacaataa
    57601 tcttatatca gctatagata aaagtattcc taatctaaat aaatatgttg agcttaaaaa
    57661 gaaattttta ggattgaatg aaatacacat gtatgatttg tatgttcctt tgacagataa
    57721 atttgacatg gatataccat atgataaagc acaggatatc atattagagg cacttaaacc
    57781 tttaggagaa gaatacttga agatcataaa aagtgctttt gatgaagggt ggattgatgt
    57841 atatgataat gaaggtaaaa aaggaggagc ttattcttgg ggaagttatg attcacatcc
    57901 ttatatatta atgagctata aaaatgacct taattctcta ttcactttaa ttcatgaatt
    57961 agggcactct gttcacagtc attattcaag aacaagtcaa ccatttttat attcggacta
    58021 taagatattc gttgcagaag ttgcatctac attaaatgaa ttacttctta taaattattt
    58081 attagaaaat tctaagtcta aggatgaaac tatatactta ttaaattatt atttagaaca
    58141 atttagaact acagttcata gacaaactat gtttgctgaa tttgaaaaaa ttgtacatca
    58201 aagggtagag agtggagaac cacttactgc tgatgaattt actaatatat actacaaatt
    58261 aaatgaaaag tattatggaa aatctgcaat agtagataaa caaataggaa tagaatgggc
    58321 gagaatacct catttttatt caaacttcta tgtatataag tatgccacag ggttttctgc
    58381 tgcaagtgct ttaagtcaac agatactttc agaaggaagt actgcagtag atagatatat
    58441 aaacttctta aaaagtggag ggtcagaata cccactagaa caattaaaat ctgctggtgt
    58501 agatatgacg aaaaaagaat ctatagagga agccttaaat gtatttgctg aattagttaa
    58561 taaactagaa aaagaattat aggatgtgat aggttgatag cttcaatgaa gacttctgat
    58621 aatatgagtt gtattatgtt tatatctgcc taaagtaact ttaaaaagtt aatctaatta
    58681 agaataaatc atataaaatt aagtttttac atgtatttaa caatatttac atttacttaa
    58741 ccctgctcta atattcattt aacaaagaat ctgtattatt aaaatataga aaaatgacaa
    58801 caaaaaatta aaatataagc gggggtaagt aaaatgttta aaaagaaaat aggcgttctt
    58861 ttagctagta caatgttagt tggagcttta gcagtaggat gtggctctaa ctcaggagat
    58921 tcaggagatt caagcaaagt ttctgtttca ggttcaactt caataggtcc tcttatggaa
    58981 actatcggag aaaagtttca agaaaaaaat caaggtgtta gtgtagaagt acaacagatt
    59041 ggttcttctg gaggtataaa aaatgctata gaaggaacat ctgaaatagg aatgagttca
    59101 agagatttaa aagatgaaga aaaaagtgct ggattaaagg aaactaaaat agcaatagat
    59161 ggtatagcat tgataactaa tactgcaaac tcagtaaaaa atctgacaat ggaccaagtt
    59221 aaaggtatat atacaggaaa gattactaac tggaaagaag taggaggaaa tgatgcacca
    59281 atagtaatag tatcaagaga agaaggttca ggaactagag atggattcca agaaattgta
    59341 gggtttgatt cagaagaact aactaaagat gcacaaataa gtgatggttc aggaaatata
    59401 aaaactacag ttgaaggaaa tgaaaatgct ataggatata tatcatttgg atatgttgat
    59461 gagaaagtaa atagtttaaa aataaatgat gttgaagcaa ctgatgcaaa tgtaatagct
    59521 aataaatatc caatatcaag accatttata ttagttaata aagaagatgg tttgtcagaa
    59581 aaaggtaaag ctttaataga ttatatatta agtgatgaag gacaagcact tgtttcagaa
    59641 aaaggattta ttaaagttaa tcaataacaa gagttataat ataaagtaaa catataatac
    59701 cctgtgagat aagctcataa aaatgatgct ttaacttgca gggtattgtc tattattgaa
    59761 tgtagaaata taaatatctt tagataaaat aggtatttta gtatcttatc tctaagaata
    59821 tggaaatatt gacaaaataa tattacaatg ttagaataaa aaagaaattt atgaaaatat
    59881 ataaaagatt tttaataaaa atattttaga aactgagaag tatatcttat tattgggcat
    59941 ctagagatat atggagttag tggtgcaacc ggctatgaat ataattttta tattgcatag
    60001 tctttttttg ttttaaaatt aacaaatatg ttgcaaaatt tgaaaatagg agtattagtc
    60061 gttaagattt ttattgatag gtaaaatttt ggcttttaaa gtagccattt gttggaaaag
    60121 ggaaattttt ttaaaagaat aatagtatta taataagaaa ataaagtttt tataaacatt
    60181 gagatgcaga atataaacct tttgtaacaa tatatttacc aaaataatac aatttatttt
    60241 atattataac catataaatc atataaatca atactcaaac tagccaatag acaagtttct
    60301 agaaaaataa taaatttata cgtgaaaatg actttaagct ccattctcca acaatcggag
    60361 actttaatta gtatttaata atgaatctta atgtttaata caatattcaa gaattattca
    60421 aaaatactta agtattatag tctagtttgt aaagatatta taaaataata ataccagtta
    60481 tatatgaaaa taaaacatta taatttgtaa taactataaa acttggaatt ataattaaaa
    60541 tacctttgaa tggagtggtg taatgtataa tttactggtt gtagatgatg atgttgatat
    60601 tttaaacata aatcaaattt atttttctaa tataggtttt aatgtatata catcagagac
    60661 tgctaaagat gctatggata tagtagagag tatagtttta gactgtataa ttttggatat
    60721 ttcattgcca gatatagatg gatataaaat gtgcaatgat ataaaagaaa aggttaacat
    60781 acctataata tttttatcta attatgagca tgaagaagaa aaagttcggg gatttttagc
    60841 tgggggggat gattatataa caaaacccta tagtttaaaa gaacttgaac ttagaatata
    60901 tgctcgtatg aggcagtaca aaaatattac atcagttcct aatgtgttaa agttttcagc
    60961 gttagtaata aatgtaaatt caagaaaagt aacttttgat ggagaaagta tagatttaac
    61021 tactatggaa tttgaaatat tattgtttct agctgaaaac aaagaacaag tattttcgaa
    61081 gatagagata tataaccaag tttggaaaat gcctgatatt ggagatcaac atacagtgca
    61141 ggttcatatt gcacagatga gaaaaaaatt aattctttaa gcagggagca tcaatacatt
    61201 caaaccgtat ggggaaaagg atataagttt gtaccataag tgagatactg taattaataa
    61261 atagttcttg ttttatttaa tactactatg aaagagatgt ggttgataca atgaaaaagt
    61321 ataatatact aaaaggaact ctcattgtat tgatagtctc tctgttggca ataacaggat
    61381 taaatcttct gtataaatat gataataaat atacatataa gtctattaga gcaagtaatg
    61441 gaattttaac tatagataat gatactttca ctaaaggtaa acttgtcttt ttgatagatg
    61501 actgggagtt ttataatcat aaaatattta aaccgaatga ttttacagag caagatataa
    61561 aaccagaata tgtttttata ggtcaatatc cagatttttc tatgagaaag gggactcagt
    61621 caccatatgg gaatgctact tatcgtatga gaataaaaaa tgaaggcaag gataagctac
    61681 taagtttaga gcttcctgag attttttccg caagtgaagt atggataaat ggagaaatgg
    61741 tttctaaatt aggagatgta ggaacagaaa aatatagacc caaaattaaa aattcagtag
    61801 taagttttat tgcaaagaaa aatacagaaa ttataatcaa tgtatcgaat ttttcacatt
    61861 attatagtgg tttgtattat ccgcctgcat taggagaaac aaaggacata agtaatatga
    61921 tgttttatcg attacttttt tatagtataa tttgcttcac aacttttgca atagctatat
    61981 tttcattgtc tgtatggttt ctttcaaaca aaagtaaaat ttacttatat tttggatgta
    62041 tgtgtgtttt ctttgccatc catgtatcct atccctttgt acatttgtta ggactgcctt
    62101 tggtaagctt tacatatgcg gttgaagatt tgtcatattt tatggtagtt ttatgtatta
    62161 tttgtataaa tggaagtata tccaaaatag aagaaaataa agtgtacaga tttttaattt
    62221 taccattagg aattacaatg agtatcatat ctatagtgat accaattatt ctttttccat
    62281 atgatatgta ctttgtcaac atatatggga agttaataga catatataaa tatattgtat
    62341 ttatatatat attaatgtct tcgctggttt caatatataa aaagacatgc tctgagcata
    62401 taagttctta tattttagtt tcagtaaaca ctgtttttgg aattagcata ttatttgatg
    62461 cagttacgag taatagattt gagcctatat ttacagggtg gcaaacagaa tattgtgggt
    62521 ttgtaattgt tattttattt tctgttatga tgataaacag gaatagaata ataataaaag
    62581 agaatgaaaa acttacaagg aatcttgaac atgaagttga agtgagaact aatgaactta
    62641 caacattgtt aaatgaacgt aaaagattct tggcagatgt agcacatgat ttaaaggcac
    62701 ctgtttcggc tatacaagca tttatagatt tgataaaggt tggtaatatt catgtagatg
    62761 aagagacaag aacctatctt tatgctataa atcaaaagtc aaatgaagta caaaatagag
    62821 tacgtagttt gcaagaattt acatcacaag ataaaagcat tggtattagt gaaaaaatat
    62881 gtctgaataa ttttattaaa gagatatatg aaaataattt gccagataca caagcatgtg
    62941 gtgtaaactt tgaagcttac gtattggaga aaaaaatata tgcaaagata aataaagaga
    63001 tgcttacaag agcatttgag aatttaattt ataatgcttt gacctttact ccatttgatg
    63061 gaaagataat tttatcaatg gataaagaag atggatttgc aattattaaa atttctgata
    63121 atggaaaagg tatacctcca gaaaatatac caaaggtatt tgacagattc tttacagaaa
    63181 gagacaataa tgagccaaaa gggcaagggt tagggctata tattgtcaaa tccattataa
    63241 gagagcatgg tggagaaatc tttgtagatt cagaactagg aaaaggaact gtttttacaa
    63301 taaaattaag tctatgtttt ttataataat agcttattta atataaaaga ataatgatat
    63361 ttgggagtga ttataatgca aactaagata ttgataatag atggagacaa ggataattgc
    63421 cagaagctaa aaggatttct ggaggaaaaa ggaataagta tagatttagc atataattgt
    63481 gaagaagcta ttggaaaaat atttagcaat aaatatgatt taatattttt agaaataatt
    63541 ctaagtgatg gtgatggatg gactctttgt aaaaaaatta gaaatgtaac tacttgtcca
    63601 attgtttata tgacttatat aaatgaagac caaagcattt taaatgcttt aaattctggt
    63661 ggagacgatt acttaataaa gcctctaaat ttagaaatat tatacgcaaa agtaaaagct
    63721 attttaagaa gaatgaactc atatgtaaat aataatgaaa ataatacaaa attagaggaa
    63781 tataatagaa ctagtggagt aataaagtta gaagataaaa taataaaatt gactccaaca
    63841 gaaaataagt tgttaaactt ttttatagag aatcctgaaa agactttgac tactaaagag
    63901 atatatgaac atgtatggat gaatgaatac ttagaggata actatagtgt ggtagttgca
    63961 gtgaatggat taagaaagaa aatagagaaa gattataaaa atcctcagaa aattataaca
    64021 ataagaggag caggatatta ttttaataaa gaataataaa tatattaata tcattaataa
    64081 ttgttataaa tgtgaaatac taacgatatc taaactaaat tattataaaa tagctgactg
    64141 taatttaatt gataaagcct attcttctag actttgccaa ttaaattaca gtcagtttta
    64201 ttatataaaa aaatgcgtaa cagaactatt attttataga ttatatttga aaagataaat
    64261 aaattgtata tctaaatcta tatattattt tttaccttta atatatatta aataataaaa
    64321 tagttaaata ataagattaa gaatttctta ataaatccag aagatgcttt cgattatata
    64381 atattttata tttttatatt attaattata tgtgttgcaa ttgctgcacc tactttttct
    64441 ggtgagtatc agacacaatc agatagcatc cttcgttgta cgaaacatgg acatattcgt
    64501 ctagcgttta ctaaaatatt agctctattt tctatattta taataatgtt tgttatatgt
    64561 atttctatcc atttggcaat ttctgattta gcttttggta ctgaatgttt gaaaacctca
    64621 tttcaaatgt tgttttctgt aattagtcta gtaaatataa atttactaca agcacagatt
    64681 cttatagcta ttggtggtct aatttcaata cttgcaatgg ttagtttaac attattttta
    64741 tctgcaaaat gtaaggattc tcttacttct atgctgattg ctttttctat ttgcttaatt
    64801 cctatgggaa taggtgttag ttggattgga tacctattac caccaggggg aattggtttt
    64861 aagattagtt tattatatca aatgacatca tttaatttct tacacttagg aggtatgagt
    64921 ttttggacac cacacattat actgtttttc tcagtgatag aaatacctat ttttatattt
    64981 ttggctattc gtacctattg caaacatcaa gtatcgtaac aatttgatgg aaataatagt
    65041 gatataaact agaggataca ataattatat atgtagtata aaagttaaat ttagttaaca
    65101 aatcttaata gcagatatag gtaataaatt atacataaac tgtattatta tctatatctg
    65161 ctattttaat atagagaaac aacagtatat tgtaaagtaa atgtcaaata tagttttaaa
    65221 agtaaaatta atgttaaaaa gtaaatataa ttttacactt gcttaactta atcctaatat
    65281 agatttaact taaaaaaagt agaataaaag tataggaaat ttgatgaaga cgaattataa
    65341 aaaattaaat tttgaataca gaacgaaaat cgataagtat attttaatgg gagggtatta
    65401 tgatagtaaa atctagatta gtaggtttag aaaaaaatga caataatggc aataagacaa
    65461 aatacgtaat tgaaaaagta gcaaaaaata tttttctact tagtgcttta gtagcagttg
    65521 caagtttact tttgataata ggattcgtat tttataaagg attaagacca tttatatttg
    65581 aaggatattc atttatagac tttttaactg gtgcagattg ggttccttct gccaataaat
    65641 ttggaatatc atctatgata gtagcatcaa tatttgcaac acttggagca cttgtgatag
    65701 gagtacctgt tggtatatta acctctgtat ttatagcaga agtagcacct aaaagattag
    65761 caaaaataat gtcaccagca gttgaacttt tagcaggtat accttcagta ttatatggtg
    65821 tatttggtct tgcagtgata gttccaacta tacaaagtat atttaatctt ccaaaaggtc
    65881 aaagtttgtt agcaatagta atagtattag cagtaatgat gttaccaaca ataatatctg
    65941 tatcagaaac agcaataaga gcagtaccaa aagcatacaa agaaggttca ttagcacttg
    66001 gtgcatcaaa aatagaaaca atattcaaag ttgtattacc tgctgcaaaa tctggagtat
    66061 tagccgcagt agtgttagga gtaggaagag ctttaggtga aacaatggca gtaatacttg
    66121 ttgcaggcaa ctcaccagtt atgccaactg caataacaga tagtgtaaga ccacttacaa
    66181 ctaatatagc acttgaaatg ggatacgcat ttggtacaca tcaagaaatg ctatttgcaa
    66241 ctggagtagt attgtttaca tttatattaa ttttaaactt agttttaaat aaactttcaa
    66301 ataaggcggt aaattaagat gagaaagttc aaagagaatc tattgaagtc attagtatat
    66361 ctatcagcac tatttacaat agtatcatta gtagttatag tgggatttat atttataaag
    66421 ggaattggca acatgaattt taatttctta tttagcaatt attcagcatc aggtgatggt
    66481 ggtatacttc caatgataat tacaacatta tatacagtag tggtttctat agttgtagca
    66541 actcctatag gaatattggc tgctatatat ttacaagaat atgctaaaaa aggaaaagca
    66601 gttacagcta taagatttgc aactgaaagt ttatcaggga taccatctat agtatatgga
    66661 ttatttggag gaattttctt tgtagttaca ttaaaaatgg gatattccat agttacaggt
    66721 tcacttacag ttgcaataat aatattacca gtaataattc gtacaacaga agaagcttta
    66781 aaaacagttc ctcaagctta tagagaatca tcattggcat taggagctac aaaatttcaa
    66841 actttatata aggtagtact tccaagtgca ataccaggaa ttttatctgg agtaatctta
    66901 tcagttggtc gtataattgg agaatcagct gcaatattac ttacagcagg tactgtagcc
    66961 aagatgccag gtggaatatt tgatagtgca agaacattaa ctgtacactc atacttactg
    67021 actaaagaga gtggagatat agcaacagca gccagtatag gaattgtttt aatagtaatt
    67081 gtattagcac taaacatgct agcaagattt gttgctaaga aattaaataa agctaattat
    67141 taaatttaag aggtgtgaat aatggaatta atcgataaga taaaaatgag tgtaaaagat
    67201 ttggatttat tttatggtga taagcaagca ttaaagaaaa taaatatgga tataaaagag
    67261 aataaggtta ctgctttaat aggtccatct ggatgcggaa aatcaacttt tataagaacg
    67321 ttaaatagaa tgaatgactt aatcgaagat gtaacaatta aaggaaacat ttctgttgat
    67381 ggagaggaca tatatacctc agatgatgtt ataaatcttc gtactaaagt aggaatggta
    67441 tttcaaaagc caaatccatt tcctatgagt atatatgata atgtggcata tggtcctcgt
    67501 acacatggac taagagataa gaagcaatta gataaaattg tagaagaaag cttaaaaggt
    67561 gcagctattt gggatgaggt taaagacagg cttaaatcat ctgcactagg actttctggt
    67621 ggtcaacaac agcgtatatg tatagcaaga gcaattgcta tgagaccaga agttattctt
    67681 atggatgaac ctacatctgc tttagaccca atttcaacat taaaagtaga ggaacttata
    67741 gaggatttaa aaaaagacta cacaatagtc atagttacac ataatatgca acaagctgct
    67801 cgtatatcag atgaaacagc ttttttctta aatggagagg ttatagaatt tagcgataca
    67861 aaaactatgt ttaccactcc tgtagataaa agaacagaag actatataac aggtagattt
    67921 ggttaaaata tataactata aaggagttag acaatggtca ataatagttt agatataagt
    67981 attgatactt taaaagaaca aacagtgctt atgatggaaa aatgtgaaga agcaatagaa
    68041 aagtctgtga cttgtatgat agagaaggat ttagagggtg caagaaaagt agtagaagat
    68101 gatgaagaaa taaataaatt aagagaagaa ataagagata agagtataga gctaatagta
    68161 ttaaagcaac caatggcaag ggacttaaga tttatttatt cattaggtaa tatatctata
    68221 gagctggaaa gaataggaga ttatgcagca aatatagcta gagaaatgtt gaagataggt
    68281 ggagaggctt atataaaaga gctaatagat attcctaaga tggcaaaaga atgtaagtct
    68341 atgatgtctc agactagaga agctttaatc ttatttgatg caagtatagc ttatgatgtt
    68401 ggaactaaag atgatattgt agatggattg tatgaacaag tacaaattga ttgtttaaaa
    68461 ataatgcatg aaaactcaaa taccatagac caaggtgtaa aacttctact tataggaaga
    68521 taccttgaaa gaattggaga ccatataaca aatgtatgtg agaagataat ttttgcaatt
    68581 gagggtaaaa tggttgagat aggataaaaa actgctttaa agcagttttt ttattgtcta
    68641 aattaagaaa gaattgataa aaaaatatga ttaatgggta aatttaaaaa attgtgatat
    68701 actaggaaca tattaaatat gaggatgcgt attttatata aggtgctttt taggaggtgg
    68761 aactttgaaa cttcaaaaga tgggtatgag gactataaaa acaggaatta gtgtcacttt
    68821 atgtatgatt cttggtgact atttagtaga gaatatgttt tattctctgg tagcatgtat
    68881 aatttctgtt caagatacag taaaaggttc tttaaagacg ggaatcaata gagtggaagg
    68941 tactatttta ggtggtataa taggattcat atttgcaatc attaaagctg gagacccatt
    69001 tttatgtggt ctaggagtaa tgtgctcaat atatttatgc aatctgttta aaataaagtc
    69061 agtagtagtt gcctgtgtaa cctttctggc tatacatcta ggtgtaggaa atagtgaccc
    69121 tgtgtattat tctttacata gggtgttaga tacatctgtg ggtgttttgt ttggagtact
    69181 tgttaattat tatgttgcta gaccaaatta tctaaatagt gttatagatg agtttaaaaa
    69241 gatagaagaa ctttcaatgt tgcttattga agataaaatt cttagaaaag aaaatttaaa
    69301 tgtagagaaa tttgaagaag aagtagaaaa attagaagaa atatattcaa aacttattga
    69361 tgagttggat tatagtttga gtgaaactaa tatagaaaaa attgagaatg ccttaaggat
    69421 atgtagagaa atacattttc atatgcagtc tatagagtta cttgaaaata aactttattt
    69481 gaaagagcat acatataaat accttaagaa aacatataat gtggataagc tagactggaa
    69541 tatagatgaa gaaaaaagcc ctgtattcaa ctatcatcta atgaaaataa tgattgaaat
    69601 agagttgttg agaaagctaa ataaatcata ttaataatag tagttaaata ataaataaaa
    69661 aatagtatct ttgtaaatat taaacatata taagtttaat ttatggaggt actatttttt
    69721 atgaatacta gaaatgacaa ttctaaaata ctagaaatat ataaaatgaa gctttttggc
    69781 gaacttgtaa aagcagtgtg gaatgatgat atagaggata ttgaaaactt acctaataaa
    69841 attttaaatg aagatttaaa ggataattta aataattatt ttagtggaaa atttgataaa
    69901 gatactatgg taaatttaat tagggtaact atgggattgg atgtgacaga agatacagat
    69961 aaaaatttaa aagagtcact acatgaagct gtaaatttag atgaagtcaa aagaccaata
    70021 atatctgtaa tatcagatgc ttgcaaatat tgtgatgaaa ataataagga agatgagtca
    70081 tgtaagataa gaagtaagca tattaattgt aatgaggaag atgtatgtag tgcttgtggt
    70141 gattgtgtat caagatgtaa gttgggtgca atttcagata aaatagaatt tataccaatg
    70201 ataaaattgt taaaagatat aaagagccct gtatatgcaa tagttgcacc agcttttgta
    70261 ggacagtttg ggaaagatgt aagccctggt aaattaagaa ctgcattaaa aaagatagga
    70321 tttgaagata tgatagaagt tgctttggca gcagatatgc ttactgcaaa agaagcatat
    70381 gattattatg agcatatgaa aaaggacgaa gaaggatgct ttataactag ttgttgctgt
    70441 cctatttggg ttagtttgat acaaaatagt tttcctcaga tattggaaaa tgtatcacca
    70501 tccgtttctc ctatgattgc ttgtgggaga gctgtaaaaa ttttaaatcc agatgctaaa
    70561 gttgtattca taggtccttg tatggcaaaa aagaaagagg caatgttaga agatataaaa
    70621 gatgcagttg attttgtgct tacatttaaa gagttgcaag aaatatttga tgcattagag
    70681 ttaaatccag caataatgga tgagagtaat agagtagagg cgtccctttc aggtagagtt
    70741 tatgctagaa caggaggtgt aagtaaagca gttaagttat cagttagaag aattgacaaa
    70801 aatataaaat ttgaagaaaa ggcatttgaa ggaacaaaag agtgcatgga cggtctaaag
    70861 aaagttctaa ataaagaaat agaagctaca tttatagaag gaatggggtg tgtaggaggc
    70921 tgtgtaggag gtccgaagcg tattttaagt gtggaagaag gtactaagaa tgttgatgaa
    70981 tatagtgaaa gtacgaatat ggaaactcca tttgataatt taaatgtatt acaattttta
    71041 acttctttgg gaatcaaaag agtagaatct ttaggagaaa aagaagaaga aaaggttaaa
    71101 aaaatattta gtagagatat aaaaagtaat aagaaagaga ataaatataa aaaataactt
    71161 tttaagtctt aaacttatgc ttttataaaa gggagatatg ggggatgaaa attaaagata
    71221 ataaggctgt ttttcatgta tttataagga tatttattat agctgtttta attttaactg
    71281 gaacattatt ggaggaaaaa attaataatg ttccagttga aaatataagt tcaaaaggtg
    71341 aaaatacact ggaactgctt tctcaaagta atactttagg agaaatcata tacaaagcat
    71401 ctcaagaaga aacaaaaggt ccaggggcta cttctgaaaa agtagcatac ataacaatag
    71461 atgatggtcc atcaaaatat acaaatgcac tacttgatat tttaaaagaa aatgatgtca
    71521 aagcgacatt tttcatgctt aatcagaata tgaaaaacca caaggaagaa gtaaggagag
    71581 tcttggaaga agaaaactca ataggttttc atagtgtaag tcatgatata cataagttat
    71641 ataaaagccc agaagtaaca gttggggaat ttaatacatg caataatact ctacaagaaa
    71701 taactggtca gagttcaaaa ttaataagat taccatacgg aagtaaacca tatatgccag
    71761 aaggttcata taataaactt atggcaaatg attatttaat ttgggactgg aatttggata
    71821 cacaggattg gaagtcttct acaagtcaga tagtaagtaa tatattatat tatggaagaa
    71881 aaagagatga attagtagta ttaattcatg agaaagagca aagtttaaat gctttaaata
    71941 atattataag aatcttaaaa gagagaggat atacaatatt gccaattaca gaaaatataa
    72001 cacctaaaaa tttctggcaa gaaaacttat aataaattta aatatagtaa aagataaagt
    72061 aaattattta taaaataaaa catataatat aaaaaatacg aataagaggt atactgtaag
    72121 gataatataa tataaaatta atgagaaagc attaaaatta aaataaaata atcttgcaat
    72181 tattgacatt ataagacaga ataactgtaa aaacatattt taaaatataa caactatata
    72241 aaagagaata gacataatta agaaaattca gaaaaaataa aataaaaata attgacaaag
    72301 agaataatat ttgtatataa taatatgtaa tattaaagac tgagaagaag aggagtaagt
    72361 aaatactact aaaagagagg aaaattcact ggctgtaaga ttttctaagt ataagattta
    72421 ctgaatgtag ctttggagtt tctaaactga actataagta agtttagacg gttagaaccg
    72481 ttaaattctt tgagagtcaa agttgataaa ataacattaa ccaataattt aattatatgt
    72541 taatgtattt taagctttgg aattaaggtg gtaacgcgag cttttcgtcc tttttaaaga
    72601 ggatgaagag ctctttttta tttctaaaga tatttaaaaa atttatttat aaaatacagg
    72661 aggcaggaca atggaaaata cgaatttatc aaaaacttat aacccaaaag attttgaggc
    72721 taggctatat aaaaaatgga tggatgaagg gtattttaaa tctaaaccaa atccagataa
    72781 aaaaccattt acaataatga tgccaccacc aaatataaca gggcaattgc atatgggaca
    72841 cgctcttgac catacacttc aagatatatt aatcagatgg aaacgtatgg atggatatga
    72901 agctttttgg cttccaggaa ctgaccatgc ttctatagca acagaagtta aagttgttga
    72961 aagaataaaa aaacaagaag gcaagacaaa gtatgaaata ggtagagaag aatttttaaa
    73021 gagagcctgg gaatggaaag atgaatttgg aggaaaaata tctaatcagc ttaaacaact
    73081 aggtgattct tgtgattggg ataaagaaag atttactatg gatgaagggt gtaatgaagc
    73141 agttatagaa ttttttgtaa gcctatatga aaaaggtcac atatacagag gaaatagaat
    73201 aataaactgg tgcccagatt gcaaaactac tttatcagat gcagaagttg aacatgaaga
    73261 acacgacgga aacttttatc atataaagta cccactaaaa gatagtgaag actttttaga
    73321 aatagctaca actagacctg agacaatgat aggagatact ggtatagcag taaatccaga
    73381 agatgataga tataaacatt taataggaaa aacagcaata cttccattag taggaagaga
    73441 acttccaata gttgcagata gttatgttga tttagagttt ggaactggtg cagttaagat
    73501 gactccagca catgacccta atgattttga agtaggatta agacataatc ttgagcagtt
    73561 aaatactatg aatgaagatg gaactatgaa tgaagtttgt ggaaaatatg aaggtatgga
    73621 tagatttgag tgtagaaaag ctatcgtagc agacttaaaa gaacaaggtt acctaattaa
    73681 gataaaagag cataatcata atgtaggaac ttgttataga tgccatacag tagttgagcc
    73741 tagattatca gagcaatggt ttgttaagat ggaagaactt gcaaaaccgg ctatagatat
    73801 tcttaaaaaa ggagaattag aatttgttcc agataaattt gataaaactt atttacaatg
    73861 gctagaaaat ataagagatt ggtgtatatc aagacaatta tggtggggtc atcaaatacc
    73921 agcttattat tgtcaagagt gtggagaaat agtagttgct agaaaaatgc cagataagtg
    73981 tcctaaatgt ggaagcactc attttaaaca agatgaagat gctttagata cttggttcag
    74041 ttctgcatta tggcctttct ctactctagg atggccaaat aagactgaag ctttagatta
    74101 ttattatcca acaagtgtac ttgttacagg atacgatata atattcttct gggtagttag
    74161 aatggcattt gcaggtatgt tctgtatgaa tgaaaagcca tttgaccatg ttttggttca
    74221 tggattagta agagattctc aaggtagaaa aatgagtaaa tctttaggaa atggtatcga
    74281 cccattggag ataatcgagc aatatggagc tgatgcccta agatttacat taacaactgg
    74341 aaattcccca ggaaatgata tgagattcta tatggaaaga gtagaatttg ctagaaactt
    74401 tgcaaataag ttgtggaatg catcaagatt tgtatttatg aatattgatg aagatataat
    74461 taaaaacatg actagagaaa gtgttaaaga ggacttaact ctagctgata aatggataat
    74521 atcaagagca aataatattg taaaagaagc aactaataac atggataagt ttgatttagg
    74581 aatagcactt caaaagatat acgattttac ttggtcagaa tactgtgact ggtatattga
    74641 aatggttaaa cctagattat atggagaaga tgcaaatgct aaatctgcag cattatatac
    74701 attaacttat gttcttgaaa aaatattaaa attattacat ccatacatgc catttataac
    74761 agaggaaata tatactcatc ttcctactgt tgaaggatgt ataatagtat ctgaatggcc
    74821 aaaatataat gaagaagata acatggctga agaagaagat atgatgaact tattgatgga
    74881 aggtataaga agtataagaa atgtgagagc agaaatgaat gtaccacctt ctaagaaagc
    74941 taaattgata ataatcccaa gtgaagaaaa aatagaagct attgagcttg gtaaagacta
    75001 ttttataact ttagcatctg cttcaaatgt agagatagca aaagataaat ctaatgttcc
    75061 agaagatgca gttggagtag ttattgatgg tgttgaaata tttatacctc ttaatgaatt
    75121 agttgatttt gaaaaagaaa ttgagagatt atctaaagaa aagaaaaagt tagaaggcga
    75181 aataaagaga gttaatggaa agcttgcaaa tcaaggtttc ttagcaaaag ctcctgaaag
    75241 tttaattgaa gaagaaaaag caaaaaaaga aaaatttgaa gagatgatta aatctgttga
    75301 ggaaagatta acaaatttag aatctaaaat aaaataaata taagaattag taaaaacata
    75361 caaaaagtat atattctata ctttttgtat gtttttcttt atatatatac aaatatgatg
    75421 ttataattct ttacagatgt gttatatttt tattttatgt tgtgaatata tgaattttat
    75481 gtcttaaaat ttataagcaa taaaaatttg atatattatg atgtttaata tagggtaata
    75541 aatacatatt atatttattt tactatattt ttttacataa tatatctaga aaagtatagg
    75601 aatttatcgt aatttaagtt taaatattaa agagaatttc tataagtagt ttaatcgaca
    75661 atttaaattt ataaagaaat ttaaatttga aagctagtga gtacagtttg gaaattgaaa
    75721 taaagtaaac taaatgatat tttagatttg gaggtgatat tatgttcagg gtagttatat
    75781 gtgatgacga aaaaatacaa agaagcatac taaaagagtt tacagaaaaa cttttgtctg
    75841 aaagatgtct aaattatcaa atactggaat tttcctgtgg agaagattta atatccaaat
    75901 acccagaaaa aattgatatt atatttttag atatccaaat gaaagatatc aatggaattg
    75961 aggtggctaa aaaaataaga aagtttgatg aaaaagtaga aattatattt acaacggctt
    76021 tttcagagta tgccccccaa ggttatgagg ttcgtgctta tagatattta gtaaagccta
    76081 tagagtatag taactttgca atgggtgtaa atctttgtat tgataacctt caaagaaaga
    76141 aggagcgtta tatagtttta aatagtaaaa aaggatttaa tagaatactg atagattcta
    76201 ttttatatgt tgaaactgta aagagagatt tagtcgtaca tacaataggt agagattata
    76261 aagctaatat gagcatgaaa caagcagaaa aattactgtg tgaaaatggc ttttttagat
    76321 gtcatacaag ttttattgtt aatttaagaa gaatagaaga tcttagggat aatatgatta
    76381 ctattaatga acaatttata cctataagta agtatagact taaagattta aaagtagcat
    76441 taacaagctt gttatgtgat ataatgtatt aattttaaaa aggtaattga aaatatcgta
    76501 aaaaagattt aatgtcatca cagggctatt gattgaaact gtcttaatat ataaaatgtt
    76561 atttatatta agacagtttt attatgcaaa atagtagttt atagattttt aatatggttt
    76621 aacatgtata tgtagagttt ccattataat agcatgatta ttaattagta gcttgattat
    76681 caatatacta ttattgattt ttatatgcat tatatgtatt tttagaatat gattaccttt
    76741 ttaaaataat gactatttat aaaactctat agatatttgt ttcatttagc tacgcatact
    76801 ttaattaatt atattaatat ttaatggagt acaatataaa tattaaagcg acatcttata
    76861 gtttattgaa cctatagtaa tgaattaata aatagtttaa ttctatgaaa agatttcctt
    76921 ttatgcaatt tatttattga aatatgatat aatatataaa ggtgtaagta ttagttgtta
    76981 aaataatatt tatattagtt tttatacata cttggtataa gtttttcata tattgattaa
    77041 aattgatgtt gatttattat ttttagtatt ttttcacctt ttgattcata ctttgtagaa
    77101 tggtgtattt tctaaaactg attataagac aagttcattc aaattagcat ttttatatca
    77161 tataaataat tgttccccct aaataagatt tagatgtata gtattaaaat caaaaagtat
    77221 aaaataaaat tgatgcttaa tcatagataa atattaataa aatatacaag gggattgtct
    77281 aataaaaaga taatctcctt ttttacaaat aattctaaat tgtgatataa atctaaaaat
    77341 tttatcttaa catttaacca tttaatgata ataattgata taataaatat aaattaaata
    77401 tatggtgtac ttattttatg tttttagcaa gaaatatagc atttaaaaga taaattgtgc
    77461 aacttaaatc aaagtttaag atgaactatt aacatagata tattaaaaac ttttgtaatg
    77521 gagaatatat gtgatatgaa taataaagtt aaggttgcag tattagatac aggaatagac
    77581 aaagaacatg attacttaaa agataattta gttggaggaa ttgcttttga atgtatgcat
    77641 gattatatct ttatatcaga taaatttgat gatgaagatg gtcatggaac tgcttgtgca
    77701 tcaataataa agaaagagta tgaagatgta gagttatttg taataaaaat tttgagaaaa
    77761 gatggtatta caaatataaa agttcttgaa gaagcattaa gatacctttt agacactaac
    77821 ataagattaa ttaatttaag tttatcagtc ataggagtag aaagtgttaa gggcttattt
    77881 gaagtttgtt atgaattgtt tagaaaagga aaaataatag tatgttcact cgctaatgat
    77941 tttgacttaa gttatccagc tatgtttaac aatgttatag gtgtaagagg atttacttta
    78001 gatggagatg attcattttg gtacaacaaa aaatatgatg ttcaatgtgt tatggatagc
    78061 aattcatata taagttgtga tataaataat tcctatagat taccaccaaa atgtaatagt
    78121 tatttatcag caaagcttac tggtaaaata gctaagatat tatcagaaaa accaggcata
    78181 acaatatctg atttaaatga taagcttgaa tcattagcaa ctagaaatca ttgggatagt
    78241 tgtgattttg atgagtgtag tagaattgta aactttaaat tggatttgta tgacaaagaa
    78301 aatgctcttc ttatgaaagt tgctgacgtt gttagggatt gcttagatat tgaagataat
    78361 aatgaaaaac tctttaaggg tagccttttt aataaggaga taggcttggt ttatgataat
    78421 tgttttaatc tgttgaaaaa gctagagcat agatttgaca taaagtttaa ttatatggac
    78481 atctcaaaat atgacttagt ttcaatatat acactgactg aattagtgga aagatataaa
    78541 aacttataaa taaagatttg tagctaaatt taatgtagaa ggtattaaat tatatgtatt
    78601 ctttgtcggt agattaaaag taaaaaatat actataatta gatagcataa gagaaaatgc
    78661 caatacaggg ggagttagat aatgaaatat gaagaagcat tagagtacat atcacaaact
    78721 aataaattcg gtataagatt aggattagaa aatatcggaa agttattaga attattagga
    78781 aatccacaag aaactttgaa tataatacat gtagctggaa ctaatggaaa aggttctgtg
    78841 tgttcttttg tttctaatat actaagagag tgtggatata aagttggttt atatacatct
    78901 ccatatttag aaacttttac tgagcgtata agagtaaatg gacaaaacat accacaggat
    78961 gatgttgcta gaataattga gttaataaaa gaaaaaatag agattatggt aaaagaaggc
    79021 tatgcatatc caacagaatt tgaagtggtt actgcaatgg cattttatta ctattcagaa
    79081 caaaaggtag actttgtggc attagaagtt ggtttaggtg gcagatatga tgctacaaat
    79141 ataataacaa aatcacttgt aagtgtgata gtatctataa gtttggacca tacaggtata
    79201 cttggagata caatagaaaa aatagcgtac gaaaaggctg gaataataaa ggaaaatgga
    79261 gtagtactag tatatgacca gactgatgaa gcaaaggatg ttataaagtc agtttgtaaa
    79321 gagaaaaaag ctaaatatat agaagttgat tttgatgata taaacataaa aaaatcagat
    79381 ataaattctc aaatatacga ttgtactgta atgaaagaaa cttatagaga ccttgaaata
    79441 aaattgatag gcgaacatca aataaacaat tctatcttgg caattagtgt aataaaatat
    79501 ctaaaagaca taaataaatt agcaaatata aatgaagaat ctataagaaa aggacttata
    79561 aatactaaat ggccaggaag aatagaaaag ataaaggaaa atccaatttt tataatagat
    79621 ggtgcacata atgaagatgg agcaaaatct ttggcaaaag cacttgataa gaattttaaa
    79681 ggtagaaaat taaccttatt aataggtatg ttagaagata aagatattga tagtgtttta
    79741 gagatattgt tgtcacattt taataaggta ataacaacaa caccaaataa cccaagggcc
    79801 ataaattcag atatattaag agaaaaagta ttaaaatatg tagatgatgt aacatcaaag
    79861 catgagatag aggatgcagt aaattataca ttagaaacat caagtgagga tgatattata
    79921 ataagtgcag gttcattata tatgattggt acagtgagaa ctttagtaaa gaaattataa
    79981 ttttataaaa taagtataca aataaaaata taaaaaagag ttgtctaaaa aatggacaac
    80041 tctttttata taaaataagt ttttaataat tttactgatg tttatataag taattatata
    80101 gattgacgta tagctttaga taattggtct gggcaagaag taccttttcc accacagtca
    80161 ataccattta atttatcagc aacttcaaga gcattttggc caattattaa gcttctaagt
    80221 cctgataaat taccattaca tcctcctata aactcagcat caacaatcac attattttca
    80281 tcaacttcaa aaatcatttc tctacaacat acaccacttg gattaaatgt tactttcatt
    80341 aaaaagacct ccattaaata ttatttcttt ttttaacatt aataataata ccaaatatat
    80401 gcgtaataat gcaactataa agcataatac aagctaatga aataatatat tattgtagta
    80461 tatgtattgt agagaggagg ggttatatga aaatctatat ttctaactac ttatcaaaga
    80521 gtattagcat agttgattat tctacacttg aactagaaaa agaaatagta ttagaagata
    80581 atatatatcc acaccatttt tgcatagaaa aagaaaaaaa tttaatatac atacctagtt
    80641 caagtaatgg gatactctat gtcttagatt taagtaatga taaaataatt gatactgtct
    80701 ctataggagg aagtcttagt caagttgtac ttagcgataa tgaattgttt gtggcaaatg
    80761 aagattctaa tagtatatat gtactagata aaaacacatt aaatccaata ggaattattg
    80821 gagttgataa tatgccacat ggatttgact ttgatagaga aagcaaaaag ttatatgtac
    80881 cgtgtataaa ctcgatagta tgtatagata caattaataa aaatatacaa aagaaaataa
    80941 atatggactt tagagcttgg catatagaac ttgataaaca aaagaaagaa atgtatatat
    81001 caacacttga tggaaagctt ataataatag atgaagtaag catggatata aaaaaggtat
    81061 tatatgaatt tttattacca gtagaaataa gatttaatta tagtggcaaa aaagtttatg
    81121 ttgctgattt gggttataat aatgtaagaa ttttagatta tacaacgagt agatacattg
    81181 gaaatattga aataaatggg attccccaag gattagaaat atctaaagat gaaaagttac
    81241 tatttgtatc agatacacaa gaaaattcag taaaagttta tgaaactgca aataacaaat
    81301 taataaaaga aatcaaggta ggaaaagagc ctacaactat aatttgtttg taggctttaa
    81361 tgtatgtctc ttataagtaa atcgataact tcggcataca tataagatgc attatttttc
    81421 cagttattgc aaataagttt tgcttgtttc tctgatgaaa catttagatt taaatctatt
    81481 aagttagact gattttctat gactctaagg ttgacaataa attcattatc actttgtttt
    81541 acaaaactag actttacttg agtatctgct agtagatttt ctttgttaga atctatatac
    81601 ttgtctattt tttcagtaac actagtaggt attcgattaa agaagtattc tagactttct
    81661 acgcctcttt gagtaagagc ataatattct ctgtcagagt ctttatatgt agtcaaaaac
    81721 ttagattcca taagctgaga taaaagctgt tgtaatgaaa aataattcat catctcagtc
    81781 tctaatacta cttgagttat ttgagaatta gttaaatcca ttttaatttt ttctaatata
    81841 tataaaatta aaagtttgtg ataggctaat tcttcagacg agttttcaaa cataaatatc
    81901 atcctccgtc aaactatttc tatatataat atattaaact aatttgtaca aaattaaaag
    81961 aacaatttgt attgtattat taatctttaa taattcatat aaaaacaatt ttataaataa
    82021 atatagagaa acagggctgc taattagcag ccctgttgat acccaggtgt caaaatttac
    82081 tatttatttt ccagccattt gtctttcagc catttcaact aatttcttag tcatatatcc
    82141 accaacatat ccattttctc tagctgttaa gttacctttg tctatgtttt catagttaga
    82201 taaacctatt tcgttagcta tttctaattt catttggttt aaagcagctt ttgcttctgg
    82261 aactactgtt ctgtttgaat ttgacatagt aaatttcctc ctcaaataat tagtttatga
    82321 tgtctaacaa cacttttatt tatgtgatgt taatactaat ttctccaaaa taaaaataat
    82381 atatacagaa aaataaaggt aaaaatgtaa aaaatataaa aaaattaaat aaatgagtat
    82441 tttagagagt ttaattaggt caatataggt tttatttttt tagttattgt cttataaatt
    82501 aaatattaca gtactttttt gagctgaaaa aaaataaatt ttaaatatag aagaaattat
    82561 ttcaaagggg gaatagtatg aaaagagaag ttaaaaggac taaagctttg atatatagtg
    82621 ttttattttt ttcattatta ttagtgttaa tatttgtttt tgtttatgga ataaaataca
    82681 tatgttctaa atctgacaat tcaaaaatgc ctatatataa agttgataca aatgagaaaa
    82741 aaatagcttt gagttttgat gtagcatggg gaactgataa tatggatgat attttaaaaa
    82801 ttttagataa acataatgta aaagctacct tctttttagt tggtagttgg gtggatgata
    82861 atgaagaaat tgtaaaagct atagatgaaa aaggacatga aattggaaat cattcaaata
    82921 ctcatgccaa tttgaaggaa atatcaaaag aagacataac aaaagagata gaaactacat
    82981 cagaaaaaat atataatata acaggaaaaa ggactaattt atttagacct ccttttgggg
    83041 acgtaaacaa taaagctatg gacatttgta gtgatttagg ttataaagta attaagtggg
    83101 atgtagattc tatagattgg aaggagcttg gaccaaatca tgtaattgag aaagtaataa
    83161 aagaatctca acctggttca atagttttat tccatgctaa tataaatgat gtagataact
    83221 atttggatac tataataagt cgactaaaaa aagatggata cagtctagtc aaaatatctg
    83281 atttgttgta taaagataat tatgtagttg attccaatgg agtgcaaaaa actaagaatt
    83341 aataagtaat aaatgtatat tttaagtaaa gttgtgataa attatatagt atatgttaga
    83401 aaagtgtcga taaaaagacg gtgtctattt tttgacactt tttatacatg tatgcaatat
    83461 caataattat agattaaatt gattaaaaaa gtgtctaata attgactttt ttttgatggg
    83521 tttaaaaatt tagaagaatt aatgaatgct gtaagacagt atttccaaag ggtataagtt
    83581 tgtttaaaag ttggcataga aattgctttg ttaataagcg atatgttcta tagaaataaa
    83641 caatatgtta agaccttata atagaaaaat agcattaaca ttatttgaac agcttataaa
    83701 aaaattaata tacttaaggg ggcgtactag ttgaacaaac tatattctat tttattaaaa
    83761 caacacgttg gtggtccaga taagccagta gtaagtgttg gagatgtagt aaaaaaagga
    83821 actctaatcg cagaaccaac tggattaggg gcaaatattt atgccagtgt tagtggaaaa
    83881 ataagtgaaa taaatgacca agcgatagta attgaagctg atgaagtaca agaagatact
    83941 tttgaaccat taaaaggaga aggtatactt gacttaatta aagaagctgg agtagtagga
    84001 atgggtggag caggattccc tactcatgta aaattaaaca tagatttaaa tggtggaaca
    84061 atattagcaa atgcagctga atgtgaacct ttattagctc ataatataaa agaaatagaa
    84121 gaaagaccag aaatagttta tcaaggtata aaatatgcta tggaagttac taatgctgga
    84181 aaaggtatgc tagcaataaa aagtaagcat ccaaaagcaa tagaagcttt caaaaaagta
    84241 ataaagccag gagacaacat agaagttgca gaattagttg atatgtaccc aatgggagaa
    84301 gagagagcaa tagtaagaga cgttctagga aaattacttg agccaactca attaccttca
    84361 gaggctaatg cagtagtaat aaacgtagaa acactaacta gaatagtaga ggctgttgag
    84421 caaaaaagac cagttatatc taaaaatata actgtagttg gtcaattaaa cagtggaaaa
    84481 gaatctatag tgtttgaaga tgtgccaatt ggaacaactg tcggagaatt aattgaaaga
    84541 gctggtggaa taaaaggtga atatggtgaa ataatcctag gaggaccttt cactggtaaa
    84601 gctactactt tagatgctcc aataactaaa actagtggtg gtataatagt tactatgcca
    84661 tttgttaatg aaaagagaaa aatgggtctt ttagtttgtg catgtggacc taatgaagaa
    84721 agaatgagag atatagcaac taaaatggga gttactgata tagtatcagt tcaaaaatgt
    84781 aaacaagctc aagaaattaa aggtgcatta aaatgtgaaa atccaggaca ctgtccagga
    84841 caagctcaaa aatgtattga atttaagaaa gctggagcag aagttatatt aataggaaac
    84901 tgtactgact gtagtaacac agtaatgggt tctgcaccaa aattaaaatt aggtgtatat
    84961 catattactg accatgtaat gagaacagtt aatcacccat taataagaag aataaaaggt
    85021 gacgtaagat taaaaataaa ataatagata aatagaagtt agacatcttt agaagtaaaa
    85081 cttaaaagtt acttctaagg atgtttttta atgtattttg agggcaatat atatattgta
    85141 aaataaatgg aaaaaataga caaaatatgc tagatattgt ataatgataa caatagctat
    85201 tacaattaat attggacaaa aataatgata ctcaagtatg tggtttgtat taatatgcat
    85261 attatattaa gtcaactatc cgatagagta aaaggttttt gtgatatttg aagatactct
    85321 atagtatctt ttttattata aaaactaatt tttgtttttt attagataag tatctaggat
    85381 actaatttat attttattga gttgttaaaa aagtgcactt aaaaagttaa aaaagaaaaa
    85441 ttaaaaacct atttatagaa actgtgaagt atatcttaaa cctgggcact taaaagatat
    85501 atggagttag tagtgcaacc tgctataaat ataaatagga gtaactttta attgtcaaaa
    85561 atatataaaa taaatacata aataagtaat tgatagaaga tagatataaa tatatttttg
    85621 aaatgctccc tgcattcata acgagtgtag agtggcagat atctgcccaa aactccttta
    85681 attgctggaa gttcctaaag ctaactaaac cacaacataa tcatgaaata aggataagtg
    85741 tgatagagtg tgcatttaat aagcacttga ggttacgaaa gtagaaaaaa ttagttagat
    85801 agcataaggt taaatcctaa gtgccttgaa aatggataat cagcaggtaa gcttcgaaaa
    85861 gaagaaactt caacgactag agagaaatct cgtacctaca agtgtgggga aatggggagt
    85921 acctaattta tggttaggta atgagatagt ctgtgcttaa tagaaatatt aagaagttca
    85981 taggagaact ggttaggagt aacgacccta attgaacaca ctaaagatgt attattgaat
    86041 aagattcata taatatttaa taattttaat tatattaagt gaatacaata tatgttttta
    86101 gtatcaggag aattttgaaa acaaaaatta aaaaatcaag tataatcagt ttagtaattg
    86161 cttttagtat ggtatttact gcatttacac caatagtatc ttatgctgac gaagtgacta
    86221 gcaatgatac aatacttaat ggagaagaac aatcaaatgg tcagacacca gatgtagaga
    86281 aaccatcaga cggtcaggta ccagatgggg agaaaccatc agacagtcaa gtaccagatg
    86341 gggagaaacc atcagacggt caggtaccag atggggagaa accatcagat ggtcagatac
    86401 cagatggaga gaaaccatca gatggtcaga taccagatgg agagaaacca tcagatggtc
    86461 agataccaga tggagagaag ccatcagata gtcagacgcc agatgtggag aaaccatcag
    86521 atggtcagat gccagatgtg gagaaaccat tagatgagca aactccagaa gaagaaaaac
    86581 cattggaaga aaaaatagtt atagaggaaa tgagtttaaa acaagatatt gataaaattc
    86641 ttgatatgac tttatctcaa ataaataaaa tagtatataa cttttgggaa gatgaagaag
    86701 atgtaaaggc agatgaacaa tcagaaatta accaagtttt tacttcaaaa gactcattta
    86761 ttagcttatg gtatgacaaa aaagcaaaag taaaaaattc ttgtttacta aaagaaatag
    86821 atggttcaga tagaccttat catgatttaa gatttgatga tattacaaag actttaactt
    86881 ttgactatgt aataaagggt cttgtaggag caagctcaaa agacgacaaa tatgtaatag
    86941 aaggtgaaga tggagagcaa actgcatttt gttacaataa tcatttaaga ccaccaagta
    87001 gtaatggaaa gagtccatat ttaccagcag aagattttaa tggtcaagaa aaccaaaatg
    87061 aagaagcagt taaatctata ctatatgcag gttctgaatt tgatggattt ggatataagc
    87121 aacaatttaa tttaggtgga gaagaaaatg aattgatgac ttactcagct actcaaagtg
    87181 caatttggat tattcttgga caaatggatg aacaagaaag acttaagcag tatcaaggtt
    87241 ctataaacct ttgtgataaa cttatagaaa gagcaaaaac tgaagaggaa agagcggagt
    87301 atcagaagag gaaagaagta gcgataaata caaaagctta tttagaagca ttgttaaaag
    87361 caggtcgtga agagttaaag ccaaatgata caggaaaacc tagtttgagt aatggtttaa
    87421 ctaagattaa ctttgaaaaa aatgaagatg gtacttatga aacagaagct gtagccttag
    87481 taggttatag tggtgtagta aagttaaaac taccagatgg agtaactgct tatgatgtag
    87541 atggtaatat aataggtaca ggcgaagtag aaatttcaac gcaacagaaa tttaaactta
    87601 agagtgttgg aaaaccagat gccaaagcta atatttctgc tgtatcttat gattatattt
    87661 ttccaaaagc tattcaatat tataaggcag tgcttgattt aggacaaaaa gaccattcat
    87721 cttcattacc atctagcaag caaaatttat taagttatac aatagagaaa aagaatggtc
    87781 aagaagttaa ctttaatata ggtttaccaa cagatgatga tgttgtaaat ccaccagtgc
    87841 caccaataga tgatgatgtt gtaaatccac cggtgccacc aacagatgat acaaatggac
    87901 ataagccaaa accatcacca ccaatagatg atacagtaat aaatccacca gtaccaccaa
    87961 tggatgatac aataataaat ccaccagtac caccaacgga ggatgcagtg ttaaatccac
    88021 cagtgccacc aatggaggat gcagtgctaa atccaccagt gccaccaaca gatgatacag
    88081 tgttaaatcc accagtacca tcagtaagtg atacagtgga aaaaactcca gaactatcaa
    88141 gagatgatac aataataaaa tcaccaaaaa caggtgatga aactcagcta atgtcatatg
    88201 tatttattag tgtcattgca atttgtggat tagcgtatca atgtaaaata aaaagaaatt
    88261 aatctagatt attattaagt ttaaaataaa aagtctcaaa ttgatttata agtcattttg
    88321 gggctttttt atgtaaatat aatatgcaaa tatagtttgt ttaaaaatat ctatcttaat
    88381 tatattctta aatttatgat tggatacagg cattcattaa ttgtttgatg aatagaaaaa
    88441 tgttttgaag gtgaaaatag tattgaaaaa ataatatact aagggtataa ttcatttgat
    88501 ttcatttgta taaatttaat t
//
LOCUS       DAMJXI010000008        82179 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.008, whole genome shotgun sequence.
ACCESSION   DAMJXI010000008 DAMJXI010000000
VERSION     DAMJXI010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 82179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 82179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..82179
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.008"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            62..691
                     /locus_tag="PC465_000830"
     CDS             62..691
                     /locus_tag="PC465_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HDF2648157.1"
                     /translation="MDEKITKNNYNVPFDYVRKKLKELDPHTISNLSNIPFNNDLNRF
                     TLNFFDRQYIIDYPNGEVWNSNGSLCNNFELKILIVRYLINAKGIPRTNKYVTFKEIP
                     GGNVYYPNFLNRTLYRLSEVFTSQIDKYKLVMEKIGAEKVNMGDLAYRFTYMGNTSMV
                     FILWFGDDEFPPNSNILFDSNIVYYFNAEDLAVVPDTAINAILNKINQL"
     gene            718..1356
                     /locus_tag="PC465_000831"
     CDS             718..1356
                     /locus_tag="PC465_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase"
                     /protein_id="HDF2648158.1"
                     /translation="MIFSTWREDGRFKLYPNGGIYPCHTANAANVLCHMGYASDIRMQ
                     KTFQHFLDTQYTDGGWRCNKFSFGRGPETEYSNPLPTLNILNAFRFSNYLNKESKLDK
                     AVDFLLDHWTIKKPIGPCHYGIGTLFMQVEYPFRNYNLFLYVYVLSFYNCAKKNNRFL
                     EALKILESKMIGNKIVVESVVPKLSKLSFCKKGESSEIAKTHYYEILKNLEK"
     gene            complement(1452..2240)
                     /locus_tag="PC465_000832"
     CDS             complement(1452..2240)
                     /locus_tag="PC465_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648159.1"
                     /translation="MCILELIKFELKKIELKHVLIFVIISILCIFITGILDYNELIFY
                     NDVPIMDTYSIAGWLGIIKISDVFIPIMSAITIIYVFSKDYSGNINEILTLYNKKKYN
                     QFIVFRWCVILAIYTVLLLISITIVYTFTSVKGFNIDKIDFVYSVKPIDVFLKTFPTL
                     LWYTTFPLMILTLTKNRFTTIAILITYTFADIFFILHMYPFVSMINVNGFYIQKMFYM
                     PNNIDVRFNELKNYFFINRGSLVVISIIIVFYIARKSTVLKKSK"
     gene            complement(2241..3113)
                     /locus_tag="PC465_000833"
     CDS             complement(2241..3113)
                     /locus_tag="PC465_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2648160.1"
                     /translation="MINKLEIRNLNFNYKNKKALDNINLTLTDGVVALLGPNGAGKST
                     LMRLLVTLYETSIGEIELNNIKYSKNNEKIKANVGYVPQDFDMYNNINGQEYLEFVAK
                     MRGVSKNDLKKHIQKVVSKVNLDKFINKKIGTYSGGVKRRLGIAQALIGDSKLIVMDE
                     PTVGLDPEQRNEFRRLLPEISKNSIVLISTHIVEDIQFNCDKLIILNQGKILYDGTIN
                     KFIDMVEVYSVVVSNDEFEYLERNIDIIDYRRVKDGVQVKYIGKNTEKLKDSLRIDTT
                     LQDAYINFLHKELK"
     gene            complement(3128..4837)
                     /locus_tag="PC465_000834"
     CDS             complement(3128..4837)
                     /locus_tag="PC465_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648161.1"
                     /translation="MSSIKVISDFITKIIRKNILFAITVIIINYHLIQRWTHISNRGI
                     SFNDYLSLSVYTCMTISILTMLNVIFYMRKSYDTVKILCRNNFDYFLGISVAVTRNNF
                     IFCCIPIIYAIAYSSLIRTLSIVTIKSTIFILIFEWFLPLTILSIVISFISVIINNLI
                     LKITLSSVFLYLTSTNMLDRVIDIKEPFFKALFKSLNIFEDQSYAYYSDFVGKVNNSA
                     YVIDKIIPTLFAITLIIVAYLILNDIRKKQIKSLIVIVVYSILFIGLNYISIDMSTYR
                     DEERSYGEYLKKSNISDIKIKSHDMKIDFKSKSNIKDRIVLLNTSNEELTNINMILDE
                     IFDIKYIKVNSENIKFNIKKDLIEVNLKESLEPNDEVTLDIEYEGYINVLTSWNQNKY
                     IATKDDIMLPPGSLAWYPKVNQSSYMAYKINLSSKSNVYSNLPLLNKTSNFLKKDYIF
                     EGKSNDIAIYAGEFKEEVKDDIKIIYPSDSNVNMDIEEKIKFLIETRNEILGDSKASV
                     DAKKYVDEVDNVMESIKRKKINMILVADLPSNEFLYEDSKGEKISITIYHWLSGNILI
                     IDK"
     gene            complement(4920..5294)
                     /locus_tag="PC465_000835"
     CDS             complement(4920..5294)
                     /locus_tag="PC465_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648162.1"
                     /translation="MNLKKKIKKLGVTFAIGTIIVSSLGTSVFADEVSTYALISKAFS
                     GKNNIISSSVYTSGSRTFKTTDSQGGFSCRLTERFSGSSPDRIVKRHEANASSKVSLS
                     GGTYYIRYEGSTNNAKTYATLN"
     gene            complement(5551..6128)
                     /locus_tag="PC465_000836"
                     /pseudo
     CDS             complement(5551..6128)
                     /locus_tag="PC465_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891808.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
     gene            complement(6187..6327)
                     /locus_tag="PC465_000837"
     CDS             complement(6187..6327)
                     /locus_tag="PC465_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HDF2648163.1"
                     /translation="MKKIALNLLKNISALSFGIAVLSANSASSWVAHQAKEPQALQKL
                     KK"
     gene            complement(6339..7655)
                     /locus_tag="PC465_000838"
     CDS             complement(6339..7655)
                     /locus_tag="PC465_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2648164.1"
                     /translation="MLTNLSVGFWNIINLVSGTIDWIIFFLVIHLVGKRKISNIRYIF
                     TTIIIIIFMAYINVVKVFPNIKILLCMVIGISFYITSYEDKIYKSIIVSLLFWLGLMV
                     AEGSAVGLVVFINKLNNINITQHENLFRIQAIIMSKVFLFIGFILFKYFKLSLDFKPK
                     DMILIGIPILSNIVSLLLIFEYNLRVNTITTENLFIFIFAILLILSSSIILLIVIGKI
                     VQDDKLNLEYELINERIKTNYRNYENINEVHDRLKYVYHDLKNHMICIKNYDTKEEII
                     SYINNLEFQISEFEHFKNTGNKTLDLILAEKISICKKYDIQIEDNINISKLNFIKNND
                     ICSIFANSLDNAIEACMDINNEIEKRIEVKATYINKFAIIKFINTKVNDIKLIDKCIQ
                     TSKDDNKIHGIGLASIKYIVNKYGGETIVNYSDNEFILKIMIPIKS"
     gene            complement(7649..8359)
                     /locus_tag="PC465_000839"
     CDS             complement(7649..8359)
                     /locus_tag="PC465_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2648165.1"
                     /translation="MINIGICDDELHYRIKIKDILSEILSSYPINYNIYEFSAGEELL
                     NNYPKDLDILIMDIQMKTINGMDTARKIREFDHKLEIIFVTSFVEFMQEGYEVKAYRY
                     ILKPINKEKISKSVLPCINEMMKKRNNYLTINVKNYVDRIKIDSITYIETDRPNILIY
                     THDDMYITKMSISKIEKILNEYGFFRCHNSYIVNLKLVESMSGSTVIVDGKSIPISKY
                     RVKGLKLAITNILGDIVC"
     gene            complement(8798..9373)
                     /locus_tag="PC465_000840"
     CDS             complement(8798..9373)
                     /locus_tag="PC465_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HDF2648166.1"
                     /translation="MKKITWEVEYISQLPVIRYCKKCGKKTEYICSGLFRVNAQHKYL
                     DIWLIYKCSNCDSTWNSTIYSRVNPKSLNPEILEQFHTNDYNLVKQYAMNMELLHRNG
                     AEVGIPEYKIVGQEININDLTQVHIISKYPCQLKVSTLLREKLGLSRKVFDEMLDCGI
                     IRSNSGVDLKKGKLNYEIMLDIGKEKQKSSN"
     gene            complement(9666..9944)
                     /locus_tag="PC465_000841"
     CDS             complement(9666..9944)
                     /locus_tag="PC465_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648167.1"
                     /translation="MSYKKAIHILPEELLELIQEYVDGECIYIPRKSNNKKEWGSNTP
                     TREELSIRNMQIYEDYQVGYDLQYLSEKYYLSLKSIQRIVLQEKRKDI"
     gene            complement(10253..11014)
                     /locus_tag="PC465_000842"
     CDS             complement(10253..11014)
                     /locus_tag="PC465_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HDF2648168.1"
                     /translation="MKNKIEISMNNFVKNYHKSNNITTKWQELLFAYASAEDDMFQKL
                     KSVVGTSHAMPKDFLENGKTIITYFIPFDESVNNSNIGGFECSEIWARAYIETNMLIS
                     NLNDFLCEELEKIGANSYAIPGSYNFDSEKLVSDWSQRHVAFIAGLGTFGLNNMLITE
                     KGCCGRIGSIITSLELEPTKRPENEYCLYKHNNSCKKCVNKCVKEALKEDGFNRNKCY
                     EMCMINEKKYTYIGGCDICGKCIVGVPCSVINPSR"
     gene            complement(11183..13084)
                     /gene="bclA3"
                     /locus_tag="PC465_000843"
     CDS             complement(11183..13084)
                     /gene="bclA3"
                     /locus_tag="PC465_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA3"
                     /protein_id="HDF2648169.1"
                     /translation="MLLIMSRNKYFGPFDDNDYNNGYDKYDDCNNGRDDYNSCDCHHC
                     CPPSCVGPTGPMGPRGRTGPTGPTGPTGPGVGATGPTGPTGPTGPTGNTGNTGATGLR
                     GPTGATGATGPTGATGAIGFGVTGPTGPTGATGATGADGVTGPTGPTGATGADGITGP
                     TGATGATGFGVTGPTGPTGATGVGVTGATGLIGPTGATGTPGATGPTGAIGATGIGIT
                     GPTGATGATGADGATGVTGPTGPTGATGADGVTGPTGATGATGIGITGPTGPTGATGI
                     GITGATGLIGPTGATGTPGATGPTGATGPTGVGVTGATGADGATGVTGPTGATGATGA
                     NGLVGPTGATGAAGTPGATGPTGATGPTGVGITGATGATGATGPTGADGATGPTGATG
                     NTGADGVAGPTGATGATGNTGADGATGPTGATGATGADGATGPTGATGATGVTGATGP
                     TGATGATGATGASAIIPFASGIPLSLTTIAGGLVGTPGFVGFGSSAPGLSIVGGVIDL
                     TNAAGTLTNFAFSMPRDGTITSISAYFSTTAALSLVGSTITITATLYQSTAPNNSFTA
                     VPGATVTLAPPLTGILSVGSISSGIVTGLNIAATAQTRFLLVFTATASGLSLVNTVAG
                     YASAGIAIN"
     gene            complement(13151..14227)
                     /locus_tag="PC465_000844"
     CDS             complement(13151..14227)
                     /locus_tag="PC465_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2648170.1"
                     /translation="MITISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGNPTLSYYRERLFKRSSNHKWVDPIHEVVPLFGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKTLEPRHQFYYSRELYYNARYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTNGGFKSNDCYGYIPSIQLSVCYDRLGESDKAIYYHEK
                     TKEIKPNDSAVLHNENYFSKFKNS"
     gene            complement(14539..15123)
                     /gene="clpP"
                     /locus_tag="PC465_000845"
     CDS             complement(14539..15123)
                     /gene="clpP"
                     /locus_tag="PC465_000845"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDF2648171.1"
                     /translation="MSLVPHVIEQTGQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSATSGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRCALPNSEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDKILSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            complement(15120..15578)
                     /locus_tag="PC465_000846"
     CDS             complement(15120..15578)
                     /locus_tag="PC465_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2648172.1"
                     /translation="MEIIDYIEENLTENLNLDKIAYIANYSKYHLHRMFTNVVGCTIH
                     QYIQRRRLTEAARQLIFTDKYIIDIAITVGYSTHQSFTLAFRNLYKESPQVYRNKDEF
                     YPIQQRFVLNLNHQIQSEKCISYANMNYKQRRDEINSYLNFNINCEVKVA"
     gene            complement(15801..17216)
                     /locus_tag="PC465_000847"
     CDS             complement(15801..17216)
                     /locus_tag="PC465_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2648173.1"
                     /translation="MWITINRNSNISLSRQIYCEIKDMILDGSLKFEQKLPSSRTLSK
                     ELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNDTFRDEKDLHTN
                     KQKNYIDFRSGVPELKLFPRKEFSKLYKQILYDLSDSDFRYGSTAGVWVLRVEISKYL
                     FRTRGIRCNPKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSV
                     VGIKVDDKGMNTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKCATENDYYII
                     EDDYDSEFRYEGQPISSLYELSPNKVIYIGSFSKILSPAIRVGFMLLPDNILESYKTL
                     KMYSDVHTETILQHVLAEFIGNGGLEKYIFRMKKLYNRKRKYLIKVLNTEFKNEFKIK
                     GEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIENILEYDHEIILGYAHLS
                     FDEIEKGVKILSKIIHMNQGT"
     gene            17331..17999
                     /locus_tag="PC465_000848"
     CDS             17331..17999
                     /locus_tag="PC465_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648174.1"
                     /translation="MLEISHKVKEIYPNIKFGVMVINITHSKPNKENFLVLKNSTIKN
                     IIEQHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIES
                     MFLAELKNLLLTAGHDLDKMELPLKIELANGSEHFYGIGGKEHILTKDDLFLSDNIGI
                     LSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKHYISSAFPDLKVNS
                     IDIF"
     gene            complement(18175..18693)
                     /locus_tag="PC465_000849"
     CDS             complement(18175..18693)
                     /locus_tag="PC465_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2648175.1"
                     /translation="MNFVELAKKRYSCRNYQDRKVEKEKLEKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGINKLSKAANIYDAPLAILVCGDKDKVWTRPFDGKQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKIPESPERHEKTR
                     VPLSEIVSYETL"
     gene            18845..19168
                     /locus_tag="PC465_000850"
     CDS             18845..19168
                     /locus_tag="PC465_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2648176.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLENL"
     gene            complement(19173..19757)
                     /locus_tag="PC465_000851"
     CDS             complement(19173..19757)
                     /locus_tag="PC465_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HDF2648177.1"
                     /translation="MKVLVFLAKGFETMEFSVFVDVMGWARNDYGHDIDVVTCGFKKQ
                     VMSTFNIQVLVDKTIEEVCVDDYDALAIPGGFEEFGFYDEAYDSSFLNLIREFNSKEK
                     IIASICVAALPVGKSGVLKNRKATTYHLKNGKRQRQLSEFDVNVVNEPIVVDKNIITS
                     YCPETAPHVAFKLLEMLTSKEQMDEVKLAMGFKL"
     gene            complement(19806..20261)
                     /locus_tag="PC465_000852"
     CDS             complement(19806..20261)
                     /locus_tag="PC465_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HDF2648178.1"
                     /translation="MDEIDLKIINSLKKNSRASTSEISRQINLSVPAVSERIRKIEQS
                     NLIQKYTIQINREKTKYKLLAFIFINTDLSKSMKEFKKTILEYDTVLECHHISGEYDY
                     LIKVLAEDTSNLEEFISVTLKEIGGIQKANTTIVLSTIKEEFNTIKDIF"
     gene            21143..22681
                     /locus_tag="PC465_000853"
     CDS             21143..22681
                     /locus_tag="PC465_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2648179.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGTGKST
                     LIKILLGEVVPDSGEIKWQPNINIGHLDQYAEINRDTTISLYLHTAFEELYKIEKEMN
                     LLYQKSAISENGQYLIKASDYQEQLIANNFYSIDNEINKIANGLGLDSIGMNRVVGEL
                     SGGQRAKVILAKLLLSNHDVLLLDEPTNFLDKEHVEWLSNYLNTFNGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKSHLREDYIRRYQAQQKKIEKEETFIRKN
                     KAGVNSKIARGRQKQLDKIERIAPPSFTGKPNIQFSEIEISAQNALTITNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPRISGDFQFSEQVKIGYYEQDL
                     KWENPDKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLSPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKVFNIE
                     KQLV"
     gene            complement(22953..23666)
                     /locus_tag="PC465_000854"
     CDS             complement(22953..23666)
                     /locus_tag="PC465_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2648180.1"
                     /translation="MDTCFNKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAI
                     SLCKIACPDVVILDIMLPDIDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGD
                     DYITKPFSPREIAFRVKAQLRRQQYQSIVPSDSEVIKIGDITIDIEGNRVYKDRNEIE
                     LTGREYHLLSYMAKNVNKIIGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSN
                     PKILITVKGLGYKLVNRID"
     gene            complement(24114..25493)
                     /locus_tag="PC465_000855"
     CDS             complement(24114..25493)
                     /locus_tag="PC465_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2648181.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNALSAINIVCPIINLIVGIGTMLATGGSAIVARKIGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCRSYLFIILVFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTISGMVFFSKNKGLLKFCIPRLDKRILFEACFNGSSEMVGQLSTAVTTFLFNAMM
                     MKLIGEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVETFSQRGSRVYEIARSGFYIFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNILNINGIWLAVPSAEILTLFLTVFCIF
                     KYKNRYKYM"
     gene            complement(25778..26572)
                     /locus_tag="PC465_000856"
     CDS             complement(25778..26572)
                     /locus_tag="PC465_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HDF2648182.1"
                     /translation="MMKKNLKIIFMLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLM
                     FNSIYSHVDSIGGWQQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQEGELDYYIT
                     KPLDPLFRLTFENINIGSSPLILASILIVLYGISELNSEITLVMIIIYIFMVLLMTLL
                     FYDVCIILRTVSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGVFKVLFYLILPYGIMS
                     TIPTQILAGTITINGLIYSILIVFLFTLFMWRFWKLGMRHYKSASS"
     gene            complement(26569..27432)
                     /locus_tag="PC465_000857"
     CDS             complement(26569..27432)
                     /locus_tag="PC465_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HDF2648183.1"
                     /translation="MSIMSNYNEASSNYSMFYKFKQSIRRYYEVAKINFKVQLIWRFD
                     VVVNMVFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLAGIDMSKSTSE
                     EICNRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKIDFAFT
                     SNPVQILISILMIFLGFIFMMKLHFFIGILSFKFLEISFFRMIIENIVEFITGTMIPL
                     VLLPETIVTVMKVFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYK
                     RMRTLFDGVGI"
     gene            complement(27410..28405)
                     /locus_tag="PC465_000858"
     CDS             complement(27410..28405)
                     /locus_tag="PC465_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2648184.1"
                     /translation="MSIIELNELTKSYRRFEKKAGFMGSVKSLFNRKYTEKTAISSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIVPSSGEISVMGYYPNKLENNFKKQYAVV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSDYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAIAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSRKIYDGSTEKLFNHFQKYKKITVSFSNETNIVFPKDCKVVEQT
                     NHKISVIVPKERGNETIKWIFDKYDVKDVMIEEEDIGSIVERIYKKGSDEYYEQL"
     gene            29108..30064
                     /locus_tag="PC465_000859"
     CDS             29108..30064
                     /locus_tag="PC465_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2648185.1"
                     /translation="MENNTIQKQLRDLSKKIWHIYILNPEEENLKFIISLLDDNLALI
                     GTGKHEFYETLEEFIIGLEKDQTESEQIDFEIIDEWYSCTKVTDEAFIVYGTLWVIEK
                     DYLEKDIYVEMDTRFTMVYRVTDDMIKLIHVHHSIPNFDQMKDEYYPKTITEKAQEAL
                     AMANEFKLKSEKDLMTGLYNRHFFEVHIKEMLKTVSHGYFYIFDLDNFKQVNDIFGHV
                     RGDEILIHFSNILTKVFVNDAIIGRLGGDEFAVFEYSNQSKENVENKAKKVLELCLES
                     NSCSIGISKLENNSDTFQSLYKQSDYALYYSKRNNKGNFSWF"
     gene            complement(30465..31355)
                     /locus_tag="PC465_000860"
     CDS             complement(30465..31355)
                     /locus_tag="PC465_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648186.1"
                     /translation="MKKNILTTMITMIIILMMSMTVMAEPYQEDETSSLKKQSANERN
                     QTNIGTMDGRVQTNAISKGANYDPKYPLKGMLTQLGLNTTGKEGWDLLYGGNPNGVEL
                     RADGKYYYINKGMEGLGFYAAALSGGSYQRIGFGKLDPIEVIADGNWISYKQAQDTLT
                     VIRNFLNSFDWRNASEMERANRAAKLVTEAKYADSKYCNIVYGNLVDKRGVCGSFASS
                     FHLLTRLMGMNSLFILNPSLNHAWNYIQIDGKWYRFDGSEISAFGGSLDFDYRKLKDA
                     TREMTTYYDAKALSILGFNQ"
     gene            complement(31533..32231)
                     /locus_tag="PC465_000861"
     CDS             complement(31533..32231)
                     /locus_tag="PC465_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648187.1"
                     /translation="MKISSQYRSQYSFRYESNINNTRINENMVKKNETVGKDTYLSNI
                     MKQKQELNDRIRDLKYRQEVYAKKINDAIKNLCKSEIRETTNNFSNIEIGIKNSIIED
                     KNKSTMLDENSTYLNTNDEKESLITKESNEKIEEEILNDEKLEELEQKKDYKEDSNKK
                     EKVSEDLSLVGKTREELENMLKNFINLTQEEIMKLESRIEKLDKDAEEYKQNSKTNIF
                     DKTDEQKKHINVLI"
     gene            complement(32767..33834)
                     /gene="rsgA"
                     /locus_tag="PC465_000862"
     CDS             complement(32767..33834)
                     /gene="rsgA"
                     /locus_tag="PC465_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HDF2648188.1"
                     /translation="MNGMKQINLQDYGLNRNFITQSMEYHDLYLARIISQEKNFYQAV
                     CVNGVLFAEVSGKLRFEATIQSDFPTVGDFVMLDRCNNKNGNAIIHHVLHRKSLFVRK
                     AAGKVNEEQVVAANIDIVFLCMSLNKDFNIHRLERYLSLTWESGAIPVVVLTKSDLCD
                     NVHRKLQVVNSIALGVDVVVTSSIEPDGYKQISKYIKPGCTVALLGSSGVGKSSLINC
                     LMGGEFLNTKEIRIDDDKGRHATTRRELFLISGGGIVIDTPGMRELGMWDVSEGLDKS
                     FADIEAYFGKCHFRNCTHTSEPGCAIWEAIAHQELSPKRWESYRRLKTEAVFADNKSE
                     YLAKKEKKFKNISKINKKIRR"
     gene            complement(33831..34232)
                     /locus_tag="PC465_000863"
     CDS             complement(33831..34232)
                     /locus_tag="PC465_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNHCP domain-containing protein"
                     /protein_id="HDF2648189.1"
                     /translation="MNYKNRKRAYYQENSCMDNFICKNCGCLVVPEGAGTQHRNHCPH
                     CLHSLHVDIIPGDRAADCDANMEPIGVWVRKNGEWAIIHRCTRCGHLSSNRIAADDNS
                     VKLMSIALKPLAQPPFPLERIIEKLEKEETE"
     regulatory      35028..35124
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            35178..35354
                     /locus_tag="PC465_000864"
     CDS             35178..35354
                     /locus_tag="PC465_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648190.1"
                     /translation="MFRDKMDRCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            35764..36402
                     /locus_tag="PC465_000865"
     CDS             35764..36402
                     /locus_tag="PC465_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648191.1"
                     /translation="MSNQRKDFDITNDMFQESIPITTKIILEDMPSNDELNHVFSKGC
                     ERKMKKRKIVLITLLLIDVLLLGSILYNLFLGKTANISMLKESWNFDIPIPNKEIEVF
                     DTQDSINGDGQSYFIQGFSEKNFKKVFNLKGGIVVSKDNINEIEKYIDKFKRDSVNIN
                     KSNKNKIEEDFKKYKLEVKKDDKYIYKRNYENYVVLIIKKDEQKLYSLIWNQ"
     gene            complement(36896..38644)
                     /locus_tag="PC465_000866"
     CDS             complement(36896..38644)
                     /locus_tag="PC465_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005338363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2648192.1"
                     /translation="MEVEIIKANNPFDESSKVRKVDRLRVAAYCRVSTDDEDQIKSYN
                     SMVKHYTELIQNNEQWVFAGVYADKAITGTKVDKREDFQRLIQDCMDGKIDMVIAKSL
                     PRFARNTLDTLKYVRMLKERKIAVYFEVEKINTLKDGEFLMTILSSVAQQEVENTSAY
                     VKKGLKMKMKRGELVGFQGCLGYDYDVATKSISINEEGAEVVRYIFDRYVAGAGSSMI
                     ARELNEQGITTIRGNSWTSSSVMGIINNEKYKGDILLGKTFTVDPISKRRLENLGEED
                     RFYIKDHHEPIISAETFARAQEIRERRNGGRKSVTPGKREKYSRQYAFSCLLECGFCG
                     ANLSRRRWHSSSKYKKTIWQCVKSTKDGKRFCPDSKGIPEQVIEEAFIESYKMLCADN
                     KDVLEEFISRVEKTLSEDSIRDKLIKLQKSADNLQAKRKRLLENYLEGIVAQDIYEET
                     DVGYERKLSDIKANLKILEQQMDDEFSLKQRVADFKKALSKNGVLEEFDRGIFESIIE
                     KVIVGGYDEDGNKDPYKITFIYKTGFKNEIGKAKERFDKSKSVSDKAKELCSHIVDEV
                     KGVCSYVSDNTCGNCS"
     gene            complement(38840..39070)
                     /locus_tag="PC465_000867"
     CDS             complement(38840..39070)
                     /locus_tag="PC465_000867"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648193.1"
                     /translation="MILPDCRAVCNPVNKMTVQDRCGQCNELPPVLQFLSANKWGEAY
                     SAYLLADKAVQGNRRIFGNLRKDDCLWKERRY"
     gene            complement(39322..39570)
                     /locus_tag="PC465_000868"
     CDS             complement(39322..39570)
                     /locus_tag="PC465_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2648194.1"
                     /translation="MKKRCKNSEEKNLLPFHIIKAASEGDVMAINTVLKHYEGYIITL
                     STRKMYDEGGRLHFCVDETLRRRLETKLITKILAFEAV"
     gene            complement(39554..39994)
                     /locus_tag="PC465_000869"
     CDS             complement(39554..39994)
                     /locus_tag="PC465_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2648195.1"
                     /translation="MKKPSCHDELTIRHRFDRLCQMSLKGEAINYYRHMDYRREHEAM
                     FSELSEKELNQLFVMDEYGVENSHFTVHGYDIEVKDTLIAEALQALSERKRNVILLSY
                     FLEMSDADIAREMNLVRSTIHEHRTRSLEILRKIMEEKADEKEM"
     gene            40510..40857
                     /locus_tag="PC465_000870"
     CDS             40510..40857
                     /locus_tag="PC465_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2648196.1"
                     /translation="MARKKKIDKEMGFRLKQARTEQKLTYEELAEKSGVSSRYIKEIE
                     NHGNVPSLEKLGQLIRALHISADPFFYPTVPADNLDYQRLLVYLSQCTEEQITTILAI
                     VEAYLRTYKNFSK"
     gene            complement(40992..41447)
                     /locus_tag="PC465_000871"
     CDS             complement(40992..41447)
                     /locus_tag="PC465_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009242487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2648197.1"
                     /translation="MNQEQTDITTGKQIRHLRTQSGMTQEELAGELNVTRQALSNWER
                     DVSEPDLNTLKKICYLFGVHMDDFAKEVITKMETYEKKEKRQFNKYDMAIGLFYGVGI
                     FLGIGIFFVGGFMTMSGAGWGASLFGGGCFSLVFGLICHAVITLRRNDK"
     gene            complement(41529..41946)
                     /locus_tag="PC465_000872"
                     /pseudo
     CDS             complement(41529..41946)
                     /locus_tag="PC465_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003505402.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            42161..42682
                     /locus_tag="PC465_000873"
     CDS             42161..42682
                     /locus_tag="PC465_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003505403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2648198.1"
                     /translation="MNPKIYLITGLMASGKSTVSDLLAKSIEKCVHLRGDVFRKMIIS
                     GRENMSATPSAEAVRQLYLRYKLTADAAKSYFDNGFSVVIQDNYYGDELNRMINYLHK
                     YPVEVIVLCPDVETIKERERYREKTGYSGFTVETLYDTFMQTTPRIGFWLDNSNQTPQ
                     QTAETILNARKSV"
     gene            42875..44794
                     /gene="tet(32)"
                     /locus_tag="PC465_000874"
     CDS             42875..44794
                     /gene="tet(32)"
                     /locus_tag="PC465_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003505402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(32)"
                     /protein_id="HDF2648199.1"
                     /translation="MKIINIGILAHVDAGKTTLTESLLYTSGAIAEQGNVDKGTTRTD
                     TMILERQRGITIQTAVTSFCWNDYKINIVDTPGHMDFLTEAYRSLSVLDGAVLVISAK
                     DGVQAQTRILFHALQKMDIPTIIFINKIDQNGIDLRRVYQSIKDKLTSDMIVMQEVSL
                     SPKITMTDISDLDKWDMIISGSDELLERYVAEDSLDIQELQYEKCKRTRCCSLFPVYH
                     GSAKDNLGTEKLIEAITETFITETDDIQSELCGYVFKVEYTERKKRLSYLRLYHGTLH
                     LRDTLLLSKKEKIKITEMCIPSNGEIVPVDHACPGEIVILADDTLKLNDILGNEKLLP
                     HKTRIDNPMPLLRTTVEPQKPEQREALLNALAEIADTDPLLHFDIDTVTHEIILSFLG
                     KVQLEVICSLLEEKYHVGVAMKEPSVIYLERPQKKASCTIHIEVPPNPFWASIGLTVT
                     PLPVGSGTQYKSEVSLGYLNQSFQNAVMEGVRYGMEQGLYGWGVTDCQICFDYGVYYS
                     PVSTPADFRFLAPVVLEQALKKAGTQLLEPYLSFTLFAPQEYLSRAYNDAPKYCAIIE
                     STRLEKDEVIFKGEIPARCIGEYRNDLNFYTNGRSVCITELKGYQETSGEPVFQPRRP
                     NSRLDKIRHMFQKIM"
     gene            44876..45331
                     /locus_tag="PC465_000875"
     CDS             44876..45331
                     /locus_tag="PC465_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009242487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2648200.1"
                     /translation="MNQKQTDITTGKQIRHLRTQSGMTQEELAGELNVTRQALSNWER
                     DVNEPDLNTLKKICFLFGVHMDDFAKEIITKMETCEKKEKRQFNKYDMAIGLFYGVGI
                     FLGIGIFFVGGFMTMSGAGWGASLFGGGCFSLVFGLLCHAVITLRRSDK"
     gene            45561..45764
                     /locus_tag="PC465_000876"
     CDS             45561..45764
                     /locus_tag="PC465_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648201.1"
                     /translation="MEYSKEDLMEAKRQIDSTLHKLRETIITFEAKETPERYKSQITL
                     AKRRIRAFEIANYFIENEIENSQ"
     gene            45966..47168
                     /locus_tag="PC465_000877"
     CDS             45966..47168
                     /locus_tag="PC465_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014256234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HDF2648202.1"
                     /translation="MMGNYLKENNVKVKDGTDVNSIMRDMMSIILEGALEQEMDEELG
                     YSKYDYRNKETDNSRNGHSQKTMHTSYGDMEIDIPRDRKGEFEPQIVKKYQNTVTQDM
                     EEKIISMYAKGMTTNDIESHMRELYDIEISDSTISRITDKILPIVKEWQERPLEEIYA
                     VVFMDAIHYHVRNEGRIVKRAVYIAIGIDMEGHKDVLGMYVGQNESAKFWLSILNGLK
                     NRGVEDILIACVDGLTGFPQAIEAVFPDTEIQQCIIHQIRNTTKFVSYKELKPLMADL
                     KRVYAAPTEEIARAELDGFDEKWSGKYPKIAKSWKDSWANLSTYFKYPEAVRRLIYTT
                     NTIEGFNRQLRKVTKSKTVFPSDESLLKMLYLAMVDITKKWTGHRQDWGQIHSQLEIF
                     FEERLSGL"
     gene            complement(47472..48017)
                     /locus_tag="PC465_000878"
     CDS             complement(47472..48017)
                     /locus_tag="PC465_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2648203.1"
                     /translation="MRYNKTIILSNGMECCLRNGTESDGQLVVDNFNLTHSETDYLLT
                     YPDENSFNVEQESQFLKEKAESEREIELLAIVDSVIAGTAGIEAIGTKYKVRHRAEFG
                     ISVVKKYWGLGIGKALLASCIECAKTAGYNQLELKVVAENERAVSMYERAGFVECGRN
                     PKGFRSRIVGFQEVISMRLEL"
     gene            complement(48075..48938)
                     /locus_tag="PC465_000879"
     CDS             complement(48075..48938)
                     /locus_tag="PC465_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2648204.1"
                     /translation="MEYRTLENTDSVCIYEAFTQAFSDYQVSVDMPFKSFETMLKRNG
                     FMPAVSVGAFADRTLVGFILNGVRDWDNEKTVYDLGTGVIPDFRRTGIMGELLNLVST
                     ICIKNKISMYQLEVIQDNEKALTLYKKQGFRINRILNCYQLTGKIKEPGVHKVWKLEH
                     PEKLQDDQWTAVKDFWTYPPSWQNAKDAVCAIAKSFSYTIVKFDGNLIGYGIVDKIKG
                     DIAQLAVHPQYRRMGVATEILLDLLKQTKSLEMRVINVDERDQALNAFLKKLKFSVFV
                     KQYEMRKHFSD"
     gene            complement(48960..49316)
                     /locus_tag="PC465_000880"
     CDS             complement(48960..49316)
                     /locus_tag="PC465_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HDF2648205.1"
                     /translation="MLRPKEVVQLWVDAFNKHDVEAITALYHENATNHQVANEPVVGI
                     EAIRTMFTAEFSTADMTAIVENIFEDGQWAILEWRDPLGLRGCGFFQVVNGKILFQRG
                     YWDKLSFLKQHNLPIE"
     gene            49722..50063
                     /gene="mobC"
                     /locus_tag="PC465_000881"
     CDS             49722..50063
                     /gene="mobC"
                     /locus_tag="PC465_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015560860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HDF2648206.1"
                     /translation="MANRTRTNRNEFHLDDKEQFILDEKFKLSGMKSKSAFLRKLILY
                     GYVYDVDYSFLREYNTELGRISSSLNQIAKRINSTNHVYQEDMDEVKELMKQVWHTQK
                     SMLSQQPLIKR"
     gene            50012..51385
                     /locus_tag="PC465_000882"
     CDS             50012..51385
                     /locus_tag="PC465_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDF2648207.1"
                     /translation="MAYTKIHAITATVDKAVAYICNPDKTDESIYISSYACAPETAAI
                     DFKYTLDHCRENSPNKAYHLIQAFAPGEVSFEEAHQIGKELADKVLEGKYSYVVTTHI
                     DKGHVHNHIIFCAADNLEHNKYHDCKQTYYRIRKLSDELCSEHNLSVIIPGGERGKKY
                     NEWQSDKNGAAWKTQIRKDINAAIKSSSTYEEFLLLMRAKGYEIKGESSGEDAPKYIS
                     FRPLGKDRFVRGSVKSLGREYTKERIKERIELKRERKAVIPKKDYAGKRLVDTSDEKF
                     QNSPGLQRWAAIENLKIAAQAYNEAGSIKELEQKIATIAATGKEAKQTVRKLENRIKD
                     LAEIIKYAEQYKANKSYNIAYKKAKNPDAYFRKHESQIILYGGARRMLEQAGISLKGL
                     NIDKLKAEYQELTAQKKELAATYKNCDKELKTLNRKLENLNQYLGRSEPLKDAPKEPD
                     RNNTPAR"
     gene            complement(52076..52279)
                     /locus_tag="PC465_000883"
     CDS             complement(52076..52279)
                     /locus_tag="PC465_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HDF2648208.1"
                     /translation="MDKFTVEEVNLMCVFEGQDRRGMIADIKNVIPHIQDSEMVELAG
                     QVLGKLETMSDEEFAEIELEAAE"
     gene            complement(52283..56854)
                     /locus_tag="PC465_000884"
     CDS             complement(52283..56854)
                     /locus_tag="PC465_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HDF2648209.1"
                     /translation="MADARTEKQKVKEITDRLEEGLKELFEGEKYKSYLNTMSKFHNY
                     SANNIQLIEMQCPDATYVAGYKAWQKNFERHVNRGERGIRILAPSPYKIKEEQEKIDP
                     VTNEPVLDRDGMPVVEEVEIKIPAFRVVTVFDYSQTDGKELPGLGVSELQGNVERYRD
                     FMEALARVSPVPIRYEGMEGDRKGYFIDLNHPIAIKEGMGEAQTAKTGVHEVAHAKLH
                     AKEVEQETGIAKDRETKEVEAESIAYTVCQHFGIDTSDYSFGYIAEWSSGKEMPELKS
                     SLDTIRRTSSELIKGIEAQLLEIDKERAAEQAQEDIILLVANTDRSEYDLLSVRGMER
                     TELFNSLHDMKDDDRQSVEAYLERAGAWVTLLGNERSEEVEEYHLDYAYNTDTYEITD
                     FKALQEERERANKPIEYADVVVRIAMPENGEYETIKIINMQSEVENALYDMLPGEGNE
                     WGGSVTDYLKEKGFECVTIMKSGGVNDGYPQFYDFEVDMGKKEIHAASELPIMQRAEQ
                     LINLMEFHRSVYGTDERNLIMNHAFKLDDMEKTTSLAYSLAEQKDDLPLLLETKEVAQ
                     AEIDALPDGMVGLSEMHEYGYLWNEMLPLTKERASELFEEGMEVYLLHSDGSETLAED
                     WGAVQGHDGLFGVEQDDWSAYLEQGLEEDAPSPEMRLLYGNESRFGIYQLKDTEETRD
                     FRFMAMDYLEMKGIPVSKENYTLVYTGELKEGMSLEDIYTRFNIDRPVDFTGHSLSVS
                     DIVVLHQDGENTSHYVDAVGYREIPEFTKELSVFSETREEKNTDIEDVAEVAENTAES
                     GIQEEADADKFTYYVIEDLSAGVGSNPEKGEVERFDSLVEAITKFKECREREDSDQTG
                     MTKAVFGFGINGKEFDVLHVKNNRNCVPLEFTQNEVENSRFKSDLQTLYQEVGFDRAE
                     VYRERTPEETKDLVKELFEFQLKTSGINDVSMYMDRFDILYEQGKMGNLMPEGEQNHI
                     LENIPFTEWKNPYIDASGREETELAFQLADRYISIQEASEGYDYTIYDMGYWKLDGGV
                     YDNPDITIRQALDEIVADLKEPAHRSALEGNIQADDELIPIDYDGLMEKAEQAEMAHL
                     EERIRNEVPEAAESKVVADFKARTEELWNGINGQTQEDIELTIYAYLQSKIDEYDMDI
                     ELVDVAVSGSRCRGLEQDNSDLDVVVEYRGGETEDFLFNTFNEDGLSIGGVKVDINPI
                     TEGKTGTLGQYLPGVESYLAERRAALQERNTEQAQEEKQTVITLTVAECGEFHNLGEY
                     HEDIASVEEAIEIFNQIPPERMNGIRSIGINIHTEGTEAYEDTQMDIVSGRTADLEIL
                     DYVPDITDNPKAVAVIAELIDKLPDIEVLGSLEKWQAAFLAAEIDQLSYDYDTYQYND
                     TVKDREAQVANIAEDIRNGNTEYLNDFLNAMISDSMREGITDLFGKGTELDDSEGVQT
                     ARKAKELLDKLAEYKPLAKIEELEECNYNMIDNVLNNEKPKEEKEHKAGRVSIKEKLA
                     EKKAVIEQRDKSGKEAPEKGTEKKSEREI"
     gene            complement(56946..57785)
                     /locus_tag="PC465_000885"
     CDS             complement(56946..57785)
                     /locus_tag="PC465_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648210.1"
                     /translation="METAEQNTKQVMEENEALKQLIELLNQQDMDGQSQDFMGIFWYV
                     AGMQMQLTAMVDELQGVREQLSQMQENQPKSVTEKLMDKVAHLQEKITSLSECLSSVR
                     NNLVETAQQAVSAFKEKGKAEMCKVLQTGISGVKSMLSDYRERLVDVMTDCEKTANQI
                     DSIGDELKQIGNSVSNVGRLLAGKGTKEVSDEKPGVGMTRVINKPVKKAVENLRKKID
                     GIDKAFEKLDRLSSSLDAGKEAEKGGRVSVKDKLSQMKEKAGQKKAPEQDKAKPKSKE
                     ECL"
     gene            complement(57872..58222)
                     /locus_tag="PC465_000886"
     CDS             complement(57872..58222)
                     /locus_tag="PC465_000886"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648211.1"
                     /translation="MGKKKTEETIVTFTVAECGEYHNLGEYHEGIRTLEEAVRLYQQI
                     PSERMNGIPSIGINLHVVGTNKLEDSQADILSGSEIDIGFISFMPEFSGNPQVQAAIK
                     EIIELFPDKEVIDY"
     gene            complement(58249..59541)
                     /locus_tag="PC465_000887"
     CDS             complement(58249..59541)
                     /locus_tag="PC465_000887"
                     /inference="COORDINATES: protein motif:HMM:NF013658.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009258273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase family
                     protein"
                     /protein_id="HDF2648212.1"
                     /translation="MNKHTISDLYQMQSLPLSAKIRMTEYRIREWVDYYGDDGVYISF
                     SGGKDSTVLLDIARKMYPKIGAVYVDTGLEYPEVREFVKQHDNVEIIRPKMNFRQIII
                     KYGYPMIGKEVAGCVYGARRYVEKLIEQEKGADSGGIIPNYSYIADLIGIDRREDREN
                     TAYKSLSRGEIPSSDIKMPVRYLILQGKYPHKENGVETSEYSKMYNKERYKFFLEAPF
                     EISDHCCSIMKKAPMHNYAKKTGKMPMTAQMASESRLRTTNWLKSGCNGFNMKSPISN
                     PMSFWTEQDVLEYIYHNHIPIADVYGEVVADCGKGQAQENSMDLGIFDTGKPVFETTG
                     CNRTGCVYCGFGCHREKSPNRWELAEKLSNPEIIDYMMRGGAFDESGIWKPDNRGLGF
                     WFVIEWINVHGNLHIIMPHREKYLGQYMTEDTDKYLVA"
     gene            complement(59602..68517)
                     /locus_tag="PC465_000888"
     CDS             complement(59602..68517)
                     /locus_tag="PC465_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3849 domain-containing protein"
                     /protein_id="HDF2648213.1"
                     /translation="MRKYDLISALSAETSKEVARNEESWKKYLNTASRLYKYPFKDQL
                     LIYAQRPDATACASIEIWNEKMHCWVNKGAKGIALIDEEGSPYTGLRYVFDISDVHKA
                     RRIGRFPQLWEMKEEHQEAVLDRLEGIYGDTNKEAGFTDRIREIAARIAQDCYGELAS
                     DMEYLKEGSFLEELDELNVAVRVRETLADSIAYMVLKRCGMDDAELAEEIQFPYIHEF
                     NTVETLSHIGDSISDLSKPVLMEIGKAIGAYDRNEASKNLVEKGLANTVDTRYNALKR
                     ESETQDIQPTTQTGNAGERGNNDESDLREKRGLSDTNVTDGRAAGGDADEVRVDEEEL
                     LTGTQEGNLHRTSAEREAERASSDHSGTGRAEDGTADSADGESRGRDGGTESSRSDEM
                     GGDDEQHQALSGGNRAERADIQPVNEEEITENKELPEPGNEENTLSGFSLSEIEKGIL
                     QFDEFMEHKCPDIAGVMLFEPDKGKQTEYIKNSYRHGEYTEFYVGEVRAGYRADENGL
                     TVWRGNYLNRTAESSVSWETVRDSIAFYMEKGEYLKEGQIPQWEEPEPKETEVYQQLS
                     LFPTIEEQIGTIEAAQAGEKYIMPAAFSLPKEQLEAILRTGGGRDNSRSRIYAKYQQG
                     KTPEEMAEFLKNEYRTTGKGFDFGNNPISVWFSESGMSIGYGMSAKENPVAVMGWQEV
                     EGIVRSMVENGTYMGANEVFLVDAVERQRVSNDLFNFFRDGIGEVPENIPIKNYNHPE
                     SITNLCELLSTQEGRDIVSGELSKAKEQLEAGEKQIKWRYVKSPEHLLSEIADLSVEK
                     REYPAQDSVEVRNEDFITQDEIDTRLTGGSSFHHGQFRIYEYFMEGHDKKDNIAFLKN
                     EYGTGGSSHALIGSDKGHEEHDAKGIRLEKGSYGSPYAKVLLKWNVVEKRISELVKAD
                     KYLSPKGKEAYAQYKKEQAEEAMRREQEKLEHGIRVECKNAIEQAIAEKFDGYTLPRD
                     TAEGVIRQYRKERVEIVLANTITHLSHDGRFSPNNKEWAKSLVLSADWQTRDYIVTSH
                     PAVLDGFTNQARRYIERDREPEKAAVPEQETESSGQKAQNPEPENNISDSEKALIERL
                     AEMSAVVKVCGVLSMKNVVGWNEDTGEVAIEDADRRLEGKAVYDALFLEAADYVLMQS
                     LSGNTEKAVEMDALLKEAQKYAARYENEPEQQREEKAAEEVSKAEPEDLSEEPEREET
                     ENIEPIPETDTEKAGQPETGSIPKEDISDTEDDFPDIDAQAVRERLEKAGIVDEQLVD
                     ENALENDPFIRQVMGDVEALTGESEEEPEKASEKEPEIDKSGAVNYHISFNEAENTGK
                     GFAPKEKFRQNIEAIRTLEKIEGEHRTATPEEQEILAKYVGWGGLADAFDSSKANWAN
                     EYQELKSLLSPEEYASARESTLNAHYTSPVIIQTIYDAVGKMGFTRGNVLDPAAGIGN
                     FYGCLPEGMKESRLYGAELDGLTGRIAKQLYPHADIKITGFENTSYPNDFFDVAVGNV
                     PFGQYKVSDRQYDKHNFLIHDYFFAKTLDKVRPGGIVAFVTSKGTMDKKNPEVRKYLA
                     QRAELLGAVRLPNTAFKENAGTEVTSDILFLKKRDRVMDIEPDWVHLTEKDGIVMNQY
                     FADHPEMVLGKMEMVSGAHGMESACLPDTSLPLSAQLKNALSHVEGSIEQADFNEIDD
                     ELAKENIPADPDVKNYSYTVVDDTVYYRENSIMKPVDVSEKAEQRIKGMVAIRDCTQE
                     LINFQLEEYPEDMIQNKQTELNQLYDDFSKKFGLISSQTNKRAFNQDSSYCLLCSLER
                     LDDEGNFIGKADMFTKRTIKKQEVVTSVDTASEALAVSLSEKAGVDLAYMSQLAGKSG
                     EEITKELAGVIFQNPVTEEWETADEYLSGNVREKLSVARTFAENHPEYAINVTSLEGV
                     QPKELDASEIEVRIGATWISTKYIEDFMRETFETPEYLFDRKAMGVQYSNVTGQWNVK
                     GKNADRGNALVNMTYGTSRANAYRILEDSLNLRDTRIFDVVTEDGKEKRVLNKKETML
                     ASQKQEAIREAFKDWVFRDPERRQDLCAKYNELFNSTRPREYDGSHLKFPGMTPDIIL
                     RPHQLNAVAHQLYGDNTLLAHCVGAGKTFEMIAAAMESKRLGLCQKSLFVVPNHLTEQ
                     WASDFLRLYPGANILAATKKDFEPANRKKFCSRIATGDYDAVIIGHSQFEKIPLSTER
                     QMAMIERQIAEIEMAIEALKAENGERYSIKQMEKTKKSLNTRLSRLNDASRKDNVVTF
                     EQLGVDKLFVDESHNYKNLFLYTKMRNVAGIAQSEAQKSSDMFAKCQYMDELTGGKGI
                     TFATGTPISNSMTELYTNMRYLQYNTLQRLGLGHFDSWAASFGETQTAIELAPEGTGY
                     RAKTRFAKFFNLPELIALFKESADIQTPDMLKLPVPEADYENIVLKPSEYQQDMVHSL
                     ADRAEAVRDRKVQPNIDNMLKITNDGRKLALDQRLINAMLPDEENSKATTCVEKAFEI
                     WEQTKEQKSAQLIFCDLSIPKGDGTFNVYEDIRDKLMAKGVPENEIAFIHDANTETRK
                     AELFAKVRSGQVRFLLGSTAKMGAGTNVQDRLIALHHLDVPWRPSDIEQQEGRILRQG
                     NMNDKVKIFRYVTEGTFDSYSWQLIENKQKFIGQIMTSKSPVRSCEDIDEAALTYAEV
                     KALATGNPYIKEKMDLDIQVSKLKLLKANHTSQKYRLEDNIVKHYPIQIASMKERLAG
                     YRADIQTYTQNKFPDKDTFSIKIGNRVYTDKKEAGAALIDMCRSAKQPNMAVTIGEYQ
                     GFKMSVSYDSFFSKFTVNLKGSISHEVEIGADPLGNLQRLSNALEGMGKRMEEVAQKL
                     ENVEHQLETAKVEVTKPFPQEAELAEKLERLTELNALLNMDEKGGDGIDMDDEPGNDG
                     EQEEMDTEEMGHDAEAVADAPFKPQINRAVSEKVAEHGKGQMLSDSPRGRISVKEKLA
                     EMRQKAYGQKMPEKPEIQKSKGKEETL"
     gene            complement(68594..68929)
                     /locus_tag="PC465_000889"
     CDS             complement(68594..68929)
                     /locus_tag="PC465_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2648214.1"
                     /translation="MLTTGDKLLNMMKEEEVSIMELSRMSGVPERTIMDILAGIREPE
                     LGVVCRIADGLGICVHELRADEEQYAISIQKDTLAKLIVVSEINGVELEELIHTILEK
                     GIEEHGFYE"
     gene            complement(68944..71064)
                     /locus_tag="PC465_000890"
     CDS             complement(68944..71064)
                     /locus_tag="PC465_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HDF2648215.1"
                     /translation="MQLVITEKPSVARSISEVIGATEISDGYMEGNGYIVSWCVGHLV
                     ELAQPESYGEQWKKWTYESLPVNPEKWQYEVKPDTKAQYDVLFQLMHREDVSATICAT
                     DAGREGELIFRLVYEMAGCDKPIKRLWISSMEESAIREGFENLQPGSDYDNLYHSALC
                     RQEADWLVGINGTRLFTVLYGGKVLKVGRVQTPTLAMLVDREAKIMNFQKEKYYMAHI
                     LMDGIDAATGRIDDKKKADEIVGACQNGQALTTSVVKEEKTVMPPKLYDLTTLQRDAN
                     RLFGFTAKQTLEYTQSLYEKKLATYPRTDSQFLSDDMGQTAESVIEAVFHSLMFEENK
                     APRPDIKRILNSKKVTDHHAIIPTMEIAKADLAALPETERKILSLVANRLLCATGEKH
                     LYETVKAEFSCNGHIFAVSGRSVTHNGWKSFEDAFKRSFKISGNQEEEKEEKKLPELS
                     EGQAFDGVQTKISEHFTSPPKHFTEDLLLSAMERAGAEDMGDDVERKGLGTPATRADI
                     IEKLVKDGFVKREKKQIIPTEDGLKLITVLPDVVKSPKLTADWENALTLVAKGELPME
                     DFMADIENMVSELIHTYHEVSDEQKKMFAQEQTVLGTCPNCGGQVVKGKFGAYCVKKC
                     GMNVSWVMGAALTDTQVKDLLAGKKILLKGLKSKAGKPYDAYIIPSGTEEYHYTKNGE
                     EKSGVQFKFVMEFPKKKSSGGKKK"
     gene            complement(71065..72696)
                     /locus_tag="PC465_000891"
     CDS             complement(71065..72696)
                     /locus_tag="PC465_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HDF2648216.1"
                     /translation="MKKKLSVRAVASLLLSALLFCMPIGAVMANSGNTVDAYAEESSA
                     GEETEEGTGTEGSKEAEESTETEPGDSGGESEEETEGGTVSGNEIPKPECTCTEKCTQ
                     YSIDKDCEACKEDYSLCEYVNPNVKITISTPSGWHNDTTKVHISIEDVAHSGNFTIKT
                     VQAKVAQNGSWTDITEDMYVEISENTTVYVLVTDQRGKTYEKNRYIKCFDFTKPTLNA
                     AVSDGLLSVQAHDTDSGIKAVYVNGYEFTELTNGVLNIRLQQFDAGYQYFTISAMDNA
                     GNMSEIYKTANPYYTDPEKEDSSEKNPAEQLPVNAQATKPSSATAQVTEHTKTDSDGN
                     TVSELSPAEQKKQAMAEAAASEEKEESGEKEKSETGKEFYTIQTASEKVFYLIIDRDG
                     EEEMVYFLTEVTENDLLNVTADNSETLPKNSAALESAIPVSEGALPNNNGEQETEEEL
                     TEEPDGDGEENTEEPEPEPEKAEENPMATYIILGVVAVIAIGGGYYFKVVRKKKEEFL
                     DEDDDEEDEEEEYEDDEENEDSEDDFFEDKEGEDE"
     gene            complement(72674..72934)
                     /locus_tag="PC465_000892"
     CDS             complement(72674..72934)
                     /locus_tag="PC465_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope biogenesis protein TolA"
                     /protein_id="HDF2648217.1"
                     /translation="MTKERIEKELTKVRAQLETLQAKQKDLEEQKRMAERAEKMDIIE
                     KHKISSEKLQLLIKFSEDEILKLLEEKENAKEMAGNEEKVIS"
     gene            complement(72944..75715)
                     /locus_tag="PC465_000893"
     CDS             complement(72944..75715)
                     /locus_tag="PC465_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HDF2648218.1"
                     /translation="MAEKKGKKKQDTAYRKEVNAEFRKGADNAFTGGGSAAYQPRDAD
                     TKKPGHGSAGKRQAEKVTQAHQETFGQKVQKSGNGQLQENQTFSEHKGVDSQKGDTRQ
                     RESNHASKAKAKKQMYQTTSGQKVQKSDAKPGQEEKPDFVRESSGFTGQDNFSQPEEM
                     EKKQPDTEDYHRRDTYRQSQKKGKYHKKRVEKEHRVKGGTKEKTENKTFTEESFAENT
                     GNLFQGEGGSEFTGSKKLQKKQRQAGKAGKKVQKARAKLPKTREYTLQRVFDEKTGKG
                     KYVVVPLDKEKPFKQEGIPKTTMRRMQNESRNFVHGKIAETEKENSAVEGAHKSEQKG
                     EELFSFVKRQIKGKEQKQRAKVAKLEKKQFKKEVNFQYQKFLEENPQIQKKALQKRLQ
                     KQRIKREYIKARKKAASAKTAEQAFEKTKNGAVTVARKLQEFARKNAGLLVTVGIMAL
                     LLMMIMVSVSSCGAMFADTQSTILAASYLSKPKEIDAADLQFTRLELDLQKEIDRVET
                     DNPGYDEYSYNLGAIGHNPFTLISYLSAVHTEFTASGVESEVQALFDEMYTLTLTPDT
                     ETRTRTVTKTGTRTVTDPVTGEETEEEYEYEEEEEYEVSILRVTLTVIPLESLVSGKM
                     DTEQAEIFSMYGETNGLLQEFASPLNLYWYYYVSSYYGYRKNEVTGNEEFHRGVDIAV
                     PTGTTVYAAHDGTVTAAAYDSHYGNYVAIEIDGYTTKYAHMDSLSVSAGQTVEKGVVI
                     GTTGNTGSSTGSHLHIECLYNGEYYNPLFYFDVGEGTLYGETPGGLPGNAIPPDAYDD
                     ASVQALMEEAAKYLGFPYVWGGSSPSTSFDCSGFVCWVFTNSGVHNLPRTTAQGIYDQ
                     CTPVSASDAKAGDIIFFTGTYNSAGAVSHVGIYCGNGTMIHCGDPISYASINSPYWQS
                     HFYSFGRLN"
     gene            complement(75715..78213)
                     /locus_tag="PC465_000894"
     CDS             complement(75715..78213)
                     /locus_tag="PC465_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HDF2648219.1"
                     /translation="MKKKQKAAVGKPKPQKNRQTPEKAGLTFSEKKRLSELRRVLAGN
                     SKEQAKPDTAQKTITFKKMYRDGICQVADTYYTKMVEFFDINYDLLEVEDQADILEEY
                     SKLINYFDPSIRFQLFLFNRQVSEQALAEQFDTPLQDDDFNDIREEYTQMLKHQSAKG
                     NNGIIKSKYIIFGVESTGIKEARSKLSNIEKDVVHNLNNIGTNARGLDGKERLRILHE
                     YFNQGTMEPFRFSFKELSESGKSVKDYIAPPGFDFRYPSRFKSGSIYGSVSYLDMIAP
                     KFTDEMIKKLLDIDDNLTLTMHMQTIDPVEAIKMIKRALTDIQKMKIEEQKKAVRSGY
                     DMDILPTDIVTYEKDTLELLDDLNTSNQKLIKMTFLITCYGRTKRELENLTQRVSGII
                     QQANCNLRCLQYLQEQGLMASAPIGCNDVGIERNLTTKSTAVLVPFCTQELFMPAPAI
                     YYGLNALSNNMIMADRKRLRTPNGVILGTPGSGKSFSAKREILSCFLITKDDIIVCDP
                     EGEYFPLVQALHGQVVRLATNSKDFLNPMDIQLSHKGDKEALKLKSDFLITLCDLIAG
                     GKDGLENDEKGIIDTCIKHIYDGYFKHPKPENMPILEDLYNALLKYEPRDVAPEMQRE
                     AKQKAVRIANSLVLYVHGSQNYFNHRTNVDANNRIMCFDIRDLGNQLKEIGMLIVQDA
                     VWNRVSQNRERKVATRYYCDEFHLLLKEKQTAIYSVEIWKRFRKWGGIPTGLTQNVGD
                     FLKSEEIEGILGNSDFVYLLNQNAKDQHILADKLGLSEKQLMHVTNSEPGSGLILFDN
                     VVIPFVDKYPANTKTFAIMNTKPEESVTKEDEEG"
     gene            complement(78161..78568)
                     /locus_tag="PC465_000895"
     CDS             complement(78161..78568)
                     /locus_tag="PC465_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HDF2648220.1"
                     /translation="MAISVPVPKDLSGIKTKVALNLTKRQIICFSGAALVGVPLYFLT
                     KGVLGTQGAAIIMVGAMLPFFFLAMYEKDGFPAEKILYFMLRQKVLTPGIRPYKSENL
                     YEQLEEREKIRKEVCFLEEKAKGGSGKAKAAEK"
     gene            complement(78997..80829)
                     /locus_tag="PC465_000896"
     CDS             complement(78997..80829)
                     /locus_tag="PC465_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HDF2648221.1"
                     /translation="MRSPENVLESLKSKACNKSYKYGRLYRNLYNPQFYLLTYQRIQA
                     KPGNMTAGTDGKTIDGMGMARINALIEKMRDFSYQPNPARRTYIPKSNGKMRPLGIPS
                     FDDKLIQEVVRLILESIYEPTFSDYSHGFRINKSCHTALKYVQKYFTGTKWFVEGDIK
                     GCFDNVDHHVLIDILRKRIADEHFIGLLWKFLKAGYMEDWNYHNTYSGTPQGSIISPI
                     LANIYMNELDSYMAEYAEKFNCGNRRKINPAFKKKLDVCRGKEQRLKRNLSKMSEEEK
                     EDLIAEIRELRRSLKSMPYSDQMDDSYKRICYVRYADDFLIGVIGSKEDAEQVKQEVG
                     CFIREKLHLEMSGEKTLITHGHDFAKFLGYEVTITKGEYSKKTKTGATRRVNNGKVLL
                     YVPHDKWLKRLLSYNALKIKYDKQNGNKEVWEPVRRIRLLHLDDLEILNQYNAEIRGL
                     YNYYRLANNVSVLNNFYYVMRYSMLKTFAGKYRTRISRIIRKYRQGKDFAVEYPKKNG
                     KVGKVLFYNNGFRRNTKVESGNPDIVARVVENYGRNSLIKRLQANKCEWCGAENVPLE
                     VHHVRKLKDLSGRKQWEIAMIGRRRKTMALCIDCHDKLHAGKLD"
     gene            complement(81405..82079)
                     /locus_tag="PC465_000897"
     CDS             complement(81405..82079)
                     /locus_tag="PC465_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007037038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2648222.1"
                     /translation="MGGIIDKITDFIKEMLQGWVLDNLGTMFTDVNDKVGTIAGEVSK
                     TPSTWNSGIFSMVRTLSENVVIPIAGLIISFVLIYELITMVIDKNNMHDFDTSLFFRF
                     LFKACIAVMLLSKTFDIVMAVFDVGSHVVTQAASSISGSTSLDVEATLTSMFNSQIDT
                     MGIGELIGLGLETMVISLCMKIMSVLITVILYGRMIEIYRASRSAAFHPKAVRGHFGN
                     PALASR"
     gene            complement(82093..>82179)
                     /locus_tag="PC465_000898"
     CDS             complement(82093..>82179)
                     /locus_tag="PC465_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002575635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2648223.1"
                     /translation="QGIKQLMSGGGIIIVAQTVIPQLSTLFS"
BASE COUNT        23900 a        17732 c        12760 g        27787 t
ORIGIN      
        1 ttaataataa gaaaactttt tataaatata cttttaattg tttaaattgg aggaaaaaat
       61 tatggatgaa aagataacaa aaaataatta taatgttcca tttgactatg ttcgaaaaaa
      121 actcaaagaa ttagaccctc atacaattag taatttaagt aatatacctt tcaataatga
      181 tttaaataga ttcacactca atttttttga tagacaatat attatagact atccaaatgg
      241 agaagtttgg aatagtaatg gtagcctttg caataacttt gagcttaaaa tcttgatagt
      301 tagatattta atcaatgcta aaggtattcc tagaactaat aaatatgtaa cttttaaaga
      361 aataccagga ggcaatgttt attatccaaa ttttttaaac aggactctat ataggctttc
      421 agaagttttt acatctcaaa tagacaaata taagttagtt atggagaaaa ttggagctga
      481 aaaagtaaac atgggagatt tagcttatag gtttacatat atgggtaata catctatggt
      541 atttatactt tggtttggag atgatgaatt tcctccaaat tcaaatatat tatttgattc
      601 taatatagtt tattacttca atgcagaaga tttagcagtt gttcctgata cagctataaa
      661 tgcaatttta aataaaataa atcaattata aatataaata atattataat aaagtttttg
      721 atatttagca catggcgaga agatggacgt ttcaaactat atccaaatgg aggtatttac
      781 ccttgtcata ctgcaaatgc tgctaacgta ctctgtcata tgggatatgc atctgacatt
      841 agaatgcaaa aaacgtttca acatttttta gatacacagt atactgatgg tgggtggcgt
      901 tgcaataaat ttagttttgg tcgaggtcca gaaactgaat actcaaatcc actaccaact
      961 cttaatatat taaatgcatt ccgttttagt aattatctaa ataaagaatc aaaacttgac
     1021 aaagctgtag attttctact tgaccattgg actattaaaa aaccaatcgg cccttgtcac
     1081 tatggaattg gaaccttatt tatgcaagtt gaatatcctt tccgtaatta taacctattc
     1141 ctttatgtct acgttttatc attttataat tgtgcaaaaa agaataatag atttttagaa
     1201 gcattgaaga tacttgaatc taaaatgata ggtaataaaa ttgtcgttga aagtgtagtt
     1261 ccaaaactat ccaaattatc tttttgtaaa aaaggcgagt caagtgaaat agccaaaaca
     1321 cactattacg aaatattaaa aaacctagaa aaataatagt tatatagata aaacatatta
     1381 aaaaatagtg gctttaaatt ttttaaagtc actattctat ataaatataa caatataaaa
     1441 aatatattaa actatttact cttttttaaa accgttgatt ttcttgctat ataaaaaact
     1501 attattatag aaataactac tagagaacct ctatttataa agaaataatt ctttaattca
     1561 ttaaatctaa catctatatt gttaggcata taaaacatct tttgaatata aaatccattt
     1621 acattaatca tactaacaaa tgggtacata tgtaaaataa aaaatatatc agcaaatgta
     1681 tatgtaatta atattgctat tgttgtaaat ctattttttg ttaatgttaa tatcattagt
     1741 ggaaatgttg tataccataa taatgtagga aacgtcttta aaaacacatc tattggcttt
     1801 acactataaa caaaatctat tttgtctatg ttaaaacctt tcactgacgt aaatgtatat
     1861 actattgtaa ttgaaattaa taataataca gtatatatag ctaatataac acaccatcta
     1921 aatactataa attgattata ttttttttta ttatataaag taagtatctc atttatatta
     1981 cccgaataat cttttgaaaa cacataaatt attgtgattg ctgacattat tggtataaaa
     2041 acatctgata tctttataat tcctaaccat cctgctatag aatatgtatc cattataggt
     2101 acatcattat aaaatattaa ctcattataa tctaatatgc ctgtaataaa tatgcataat
     2161 atagaaataa ttacaaatat taacacatgt ttaagctcta tttttttaag ctcaaatttt
     2221 attaactcca atatacacat ttattttaac tccttatgta aaaagtttat ataagcatct
     2281 tgtaaagttg tatctatcct taagctatct ttaagtttct ctgtattttt acctatatac
     2341 tttacttgca caccatcttt aactctccta taatcaataa tatcaatatt acgttctaaa
     2401 tattcaaatt catcattaga aactactacc gaatacacct caaccatatc aataaactta
     2461 ttaattgtac catcatataa tattttgcct tgatttaata taattaattt gtcacagtta
     2521 aattgtatgt cttctactat gtgagttgaa attaatacta tagaattttt acttatttct
     2581 ggtaacaatc ttctaaattc attcctttgc tctggatcaa gaccaactgt aggttcgtcc
     2641 ataactatta acttagaatc acctattaaa gcctgtgcta tacctagtcg tctctttaca
     2701 ccacctgagt atgtacctat ttttttattt ataaacttgt ccagattaac ttttgatact
     2761 actttttgta tatgtttctt taaatcattc ttagatacac ctctcatttt agctacaaat
     2821 tctaagtatt cttgcccatt tatattatta tacatatcaa aatcttgagg tacatatcct
     2881 acatttgcct tgattttctc attgtttttg ctatacttta tattatttaa ttctatctct
     2941 ccaattgaag tttcataaag agtcactaat aacctcatta atgttgattt tccagcacca
     3001 ttaggaccta ataatgcaac tactccatct gttagggtta aatttatatt atccaaagct
     3061 tttttatttt tgtaattaaa atttagattt cttatttcta acttgtttat catattaacc
     3121 tcctttatta tttatctatt ataaggatat ttcctgaaag ccaatgataa atagttatgc
     3181 taattttctc tccctttgag tcttcatata aaaattcatt gctaggtaag tcagcaacta
     3241 atatcatatt aatttttttt ctttttattg attccataac attatctact tcatctacat
     3301 attttttagc atctacagat gctttgctat cacctaatat ttcatttctt gtttcaatta
     3361 aaaatttaat tttttcctct atatccatat ttacattact atctgatgga tagattattt
     3421 ttatatcatc ttttacctct tctttaaact cacctgcata tattgcaata tcatttgact
     3481 ttccttcaaa tatataatct ttttttaaaa aattactagt cttattcagt aaaggtaaat
     3541 ttgaatagac attactttta gaacttaaat ttattttata agccatataa cttgattgat
     3601 ttacttttgg gtaccacgct aaagaacctg gtggaagcat aatatcatct ttagtagcta
     3661 tatatttatt ttgattccaa gatgtcaaca cattaatata gccttcatac tctatatcta
     3721 atgtcacctc gtcattaggc tctaaacttt cctttaaatt aacttcaatt aaatcctttt
     3781 ttatgttaaa ttttatattt tccgaattta cttttatata ttttatatca aatatttcat
     3841 ctaaaatcat attaatattt gttaactctt catttgatgt gtttaataaa acaattctat
     3901 cttttatatt tgacttgctt ttaaagtcaa tcttcatatc atgcgatttt attttaatat
     3961 cactaatatt agatttcttt aaatactctc cataactacg ctcctcatct ctatatgttg
     4021 acatatctat tgatatataa tttaatccaa taaataaaat actgtacact actataacta
     4081 ttaatgattt aatctgtttc tttctaatat catttaatat cagatatgct actattatta
     4141 aagtaattgc aaatagtgta ggtataatct tatctataac atatgctgaa ttattaactt
     4201 tccctacaaa atcagaatag taagcatatg attgatcttc aaatatgtta agtgatttaa
     4261 ataatgcttt aaaaaatggt tctttaatat caataactct atccaacata ttagttgatg
     4321 ttaaatataa aaatactgat gataaggtaa tctttagtat taaattattt ataataactg
     4381 aaataaatga tatcactata gataaaatag taagtggtaa aaaccattca aatatcaata
     4441 taaatatagt tgatttaatc gttacaattg acaatgttct tattaaactt gagtatgcta
     4501 tagcatatat aattggtatg caacaaaata taaagttgtt tctagttaca gcaacagaaa
     4561 tacctaaaaa ataatcaaaa ttatttctac ataatatttt tacagtatca taactttttc
     4621 tcatataaaa aattacattt aacatggtta aaatactaat tgtcatacaa gtatatacac
     4681 tcaaggataa gtaatcatta aatgaaattc ctctattgga tatatgtgtc catcgttgta
     4741 tgagatggta atttataata ataactgtta ttgcaaataa aatatttttt ctaattattt
     4801 tggttataaa gtctgatata accttaatac tactcatatt tatgcccctc ctagccagtc
     4861 ttttgattat aacaattaca aaaacatcct ataaaaataa ttataggatg cttttaatac
     4921 taatttaaag ttgcatatgt tttagcatta ttcgttgaac cttcatacct tatatagtat
     4981 gttcctcctg ataaactaac ttttgaagaa gcatttgctt catgtctttt tacaattcta
     5041 tctgggctag atcctgagaa tctttctgtt agcctacaag aaaatccccc ttgagaatct
     5101 gtcgttttaa aggttctact tccagaagtg tatactgaac tagatataat attgttttta
     5161 cctgaaaaag ctttagatat taaagcatat gtgctaacct catctgcaaa tacagatgtc
     5221 cctaaacttg atacaattat agttcctatt gcaaatgtaa ctcctaactt tttaattttt
     5281 ttcttcaaat tcattgtatg tatccctccc cttagttaat ataattttta taaaaatgta
     5341 atttcaaatt acattttcat actatcgtat taacttttac aattcaatac tctgttacaa
     5401 actggttatt aagtgaatct atttgtcctt tgatacaacc cacaatagat tcaactatat
     5461 ttaataagtt caaatactta ccttgacatt atttttttaa agttaatatt aattagtgaa
     5521 gttaattaat ttagaaaatg ttttataatc ttactgatca ctattaacct tcattccaat
     5581 atatattaat atagcaatcc aatatataga aattattgca taaatcatat attgctgaaa
     5641 aatattaagt attttacata aaataattaa acatattatt acgaatagta ttttttgcac
     5701 agtctttcta taatgctttt tctcactttc actaagaggt ttgtttctat gttctaaagg
     5761 agctaacttg taaattgtta gtatactaat aatcattaat aatactaata aatacttata
     5821 tttatatcta tattattagc tgaaaaaata gttatcaaat aaataactgc aaatgttaat
     5881 gtacactctt tataattcct agcatgataa cctcctgtga actgtcttaa agtgcaataa
     5941 caacttaaaa atataactgt atgtataaat ctatcaaaaa taattcctat aaataatgct
     6001 accaaaatat taactatgaa ataaatcaaa gtttcaaatc catatctata tatttcaaaa
     6061 tcttcacttt ctacaatctc attattaact aatatattgg caaatttata tgataatctt
     6121 ttaaacatat ttcctcctca acatgtaaaa cctctccttt aataagaaga ggtcctttta
     6181 ttaatgttat ttttttagtt tttgtaaagc ttgtggctct tttgcctgat gtgctaccca
     6241 agaacttgca ctgtttgctg ataatacagc tatcccaaaa cttaatgctg agatgttttt
     6301 aagtaagttt aacgctattt ttttcatttt gtactctcct aactttttat tggtatcatt
     6361 atttttaata taaactcatt atctgagtaa ttaactattg tttcaccacc atatttattt
     6421 actatatatt taatactagc aagtcctatt ccatgtatct tattatcatc cttactagtt
     6481 tgaatacatt tatcaataag tttaatatca tttaccttag tatttataaa ttttattatt
     6541 gcaaatttat ttatatatgt agctttaact tctattcttt tttctatctc attatttata
     6601 tccatacatg cttcaattgc attatctagt gaatttgcaa atattgaaca tatatcatta
     6661 tttttaataa agtttaattt agatatattt atgttatctt caatttgaat atcatacttt
     6721 ttacaaatac ttattttttc tgctaaaatt aaatctaatg ttttatttcc agtattttta
     6781 aaatgttcaa attcacttat ctgaaactct aagttattta tatatgatat aatttcttct
     6841 ttagtgtcat aattttttat acaaatcata tggtttttca agtcatgata aacatatttt
     6901 aatctatcat gaacttcgtt tatattttca taattcctgt agtttgtttt tattctttca
     6961 tttataagtt catactctag atttaattta tcgtcttgta caattttccc tattactatt
     7021 aaaagtatta tacttgatga taaaatcaat aaaattgcaa atataaatat aaataagttt
     7081 tctgtagtaa ttgtattgac tcttaaatta tattcaaata taagtaataa gctaactata
     7141 ttagataata taggtattcc tattagtatc atatctttag gtttaaaatc taaagataat
     7201 ttaaaatact taaacaatat aaaacctata aataaaaata cctttgacat aataatagct
     7261 tgtattctaa ataagttttc atgttgtgtt atgttaatat tatttaattt atttataaat
     7321 actactagac ctactgcaga accttcagca accattaatc ctagccaaaa caataaacta
     7381 actattatac ttttatagat tttatcttca tatgatgtta tataaaatga tattcctatt
     7441 accatacata gaagaatctt aatatttgga aacactttaa ctacatttat gtatgccata
     7501 aatataatta taattattgt tgtaaatata tatcttatat tagatatttt cctctttcca
     7561 actaagtgga ttactaaaaa aaatataatc caatctatag tacctgaaac taaattaata
     7621 atattccaaa atcctacact taaatttgtt agcatactat gtcccctaat atattagtta
     7681 tcgcaagctt caagccttta accctatatt tacttattgg aatacttttt ccatctacta
     7741 taacagtact tccactcatt gattctacta attttaagtt aactatatag ctattatgac
     7801 atctaaaaaa tccatattca tttaatatct tttctatttt agatatactc attttagtaa
     7861 tatacatatc atcatgtgta taaatcaata tattcggtct atctgtttct atataagtaa
     7921 tagaatctat tttaattcgg tctacataat tttttacatt tatagttaag taattatttc
     7981 tctttttcat catctcattt atacaaggta atacactttt agaaattttt tctttattta
     8041 ttggctttag tatatatctg tatgctttta cctcataacc ttcttgcata aactctacaa
     8101 atgaagtaac aaatattatt tctaacttat gatcaaactc tcttatcttc ctagcagtat
     8161 ccataccatt tattgttttc atttgtatgt ccataattaa tatgtctaaa tctttaggat
     8221 agttatttag taactcttct cctgctgaaa attcatatat gttataattt ataggatatg
     8281 aacttaatat ttcacttaat atatctttta tttttattcg ataatgtagt tcatcatcac
     8341 atattcctat attaatcaca attcttaaac atcctttctt atatattttt aataaaaata
     8401 tataaatttc tattcatttt acatatttta acatacttct gtagtaaata gctatttaga
     8461 ttttaatttt agctttttgg acattaagta ttactttttg gatttgcaat ctattttgat
     8521 tttcattata atacaatttt ttaatatata ttaaatatat ttagggattt taataaaata
     8581 ttcctcgaaa agtttttaat atctagtttt tgttaaataa aaagtatgca ccttcctttt
     8641 tatagtaatg ttttaattat cgctataaat ttgaagaata cacactttat tttaaatact
     8701 catataaaac atattaaaaa atagtggctt taaatttttt aaagtcacta tttttttaaa
     8761 tgatgttcct gaaaatatat taagttagtt attctaatca atttgaagac ttttgcttct
     8821 ccttgcctat atctaacata atttcataat ttaatttacc tttctttaaa tcaactcctg
     8881 agttacttct aataatccca caatccaaca tttcgtcaaa taccttccta gataaaccta
     8941 gtttctcacg taataatgtt gataccttta actgacatgg atatttacta ataatatgaa
     9001 cttgtgtaag gtcattaata ttaatttctt gtcctactat tttatactct ggaataccaa
     9061 cttctgctcc atttctatgt aaaagttcca tattcatagc atattgctta acaagattat
     9121 aatcatttgt atggaattgt tctagtattt ctggatttaa gctttttgga ttaacacgag
     9181 aatatatagt tgagttccat gttgaatcac aatttgaaca cttgtatatt aaccatatat
     9241 ccaaatattt atgttgagca ttaaccctaa ataaacctga acaaatatat tcagtctttt
     9301 ttccacattt tttacaatac ctaattacag gtaactggga gatatattcc acctcccaag
     9361 taattttttt cataaatgca atttcctttc tataagatta ctaaattaat agaaagttat
     9421 gaaaaggtgg aatataatca agtatttttt tcaaaacaag acctcctaat tttaataaat
     9481 tttaatttca aacatataaa aagctactac ttcttattag atactttaca accagctttg
     9541 ttagctactg tataagttat tgaaattact taaattatat catccactta aaagaaacta
     9601 tacctcaaac acttttatca aaagaaaatg agccagtata attataaaac tatactggct
     9661 catccttaga tatcttttct tttttcttgt aatacaattc tttggatact tttcaaagat
     9721 aaataatact tttccgataa atattgcaaa tcatatccaa cttgatagtc ttcgtaaatc
     9781 tgcatatttc taattgacaa ctcttcacga gtaggtgtat tacttcccca ttctttttta
     9841 ttattagatt ttctaggaat atagatacat tcaccatcta catattcctg tattaattca
     9901 agtaattctt ctggtaatat atgtattgct tttttatagc tcattttgct ctcctattaa
     9961 atagtaattt ttcattagga atagcaaagg gctatttata tattaaattt catagttgca
    10021 atagcccttg ctatgcaaaa ataaagatta aatcaaacat aaaatctcaa ccctccttat
    10081 atatcacagc gatacatata agtctatcaa cagtataact ggttgtcaat caacacaaat
    10141 tatttatcca ttttttaaac acatttattt agtttttata ttatatttat tttgataact
    10201 aaaatttttt cattataaac tatctttaaa attattagtc aacttaagtc cattatcttg
    10261 atgggtttat tactgaacaa ggaactccaa ctatacactt tccacaaata tcacatccac
    10321 ctatataagt gtattttttt tcatttatca tacacatttc ataacactta ttcctattaa
    10381 atccatcttc ttttaaagct tctttcacgc atttattgac acattttttg caactattat
    10441 tatgtttata caagcagtat tcattttctg gtcttttagt tggctctaat tctaaacttg
    10501 tgattatgct tcctattctt ccacaacacc ctttttctgt aataagcata ttatttaaac
    10561 caaaagttcc aagacctgct atgaatgcta catgtctttg tgaccagtca cttaccaatt
    10621 tttcactgtc aaaattatac gacccaggaa tagcatatga attagcccct atcttctcta
    10681 gttcttcaca taagaaatca tttaaatttg aaatcaacat attagtttct atgtacgctc
    10741 ttgcccatat ttcagaacat tcaaaccctc caatattact attatttaca ctttcatcaa
    10801 aaggtataaa atatgtaatt atagtttttc cattttccag aaaatctttt ggcatagcat
    10861 gagatgttcc tacaacactt tttagcttct gaaacatatc atcttcagca gatgcataag
    10921 caaacaaaag ttcttgccac tttgtagtta tattatttga tttatgataa ttttttacaa
    10981 agttgttcat tgatatttca atcttatttt tcatagtatc acccctagat aattctatat
    11041 ttccaattta atgttattat tttatattat ataatagtat tttataatat gcgcactaat
    11101 taatattaaa actatgttca tcaatcattc ttaaaaaagc tcctaatatc aatacgatat
    11161 tagaagcctt ttcttatcta atctaattta ttgcaattcc tgcacttgca tatcctgcta
    11221 cagtattaac taatgaaaga cctgaagctg ttgcagtaaa tactagtaag aatcgagttt
    11281 gcgctgttgc tgctatattt aatcctgtta caattccact agaaattgaa ccaactgata
    11341 atatacctgt aagtggtgga gctagtgtaa ctgtcgctcc tggtacagct gtaaatgagt
    11401 tatttggtgc agtagattgg taaagtgttg ctgtaattgt aattgttgaa ccaacaagtg
    11461 aaagtgctgc tgttgtactg aagtatgctg aaatagatgt tattgttcca tctcttggca
    11521 ttgaaaatgc aaagttagtc aatgttcctg ctgcgtttgt aaggtctatt actccaccaa
    11581 ctatacttaa tcctggagct gaactaccaa atccaacaaa tccaggtgta cctactaatc
    11641 ctccagctat agttgtaagt gatagtggta tacctgatgc aaaaggtatt attgcactag
    11701 cacctgttgc tcctgttgct cctgttgctc ctgttgggcc tgttgctcct gtaactcctg
    11761 ttgcccctgt tgctcctgtt ggacctgttg ctccatctgc ccctgttgct cctgttgctc
    11821 ctgttggacc tgttgctcca tctgctcctg tatttcctgt tgctcctgtt gctcctgttg
    11881 gacctgctac tccatctgct cctgtatttc ctgttgctcc tgttggacct gttgctccat
    11941 ctgctcctgt tggacctgtc gctcctgttg cccctgttgc tcctgttatt cctactcctg
    12001 ttgggcctgt tgctcctgtt ggacctgttg ctccaggtgt tcctgctgct cctgttgctc
    12061 ctgttgggcc tactaatcca tttgctcctg ttgcccctgt tgctcctgtt ggacctgtta
    12121 ctcctgttgc tccgtctgct cctgttgctc ctgttactcc tactcctgtt gggcctgttg
    12181 ctcctgttgg acctgttgct ccaggtgttc ctgttgcccc tgttggacct attaatcctg
    12241 ttgcccctgt tattcctatt cctgttgctc ctgttggacc tgttgggcct gttattccta
    12301 ttcctgttgc tcctgttgct cctgttgggc ctgttactcc atctgctcct gttgcccctg
    12361 ttgggcctgt tgggcctgtt actcctgttg ctccatctgc ccctgttgct cctgttgctc
    12421 ctgttggacc tgttattcct attcctgttg ctcctattgc ccctgttgga cctgttgctc
    12481 caggtgttcc tgttgctcct gttggaccta ttaatcctgt tgctcctgtt actcctactc
    12541 ctgttgctcc tgttgggcct gttggacctg ttactccaaa tcctgttgcc cctgttgctc
    12601 ctgttggacc tgttattcca tctgctcctg ttgctcccgt tggacctgtt ggacctgtta
    12661 ctccatctgc tcctgttgct cctgtcgctc ctgttgggcc tgttggacct gttactccaa
    12721 accctatagc tcctgtcgct cctgttgggc ctgttgcccc tgttgctcct gttggacctc
    12781 ttaatcctgt tgctcctgta ttccctgtat ttcctgttgg gccagtcgga ccggttggtc
    12841 ctgttgggcc tgttgcccct actcctggac ctgttggacc cgttggacct gttgggccgg
    12901 ttctacctct tggacccatt gggcctgttg gacctacaca tgatggtgga cagcaatgat
    12961 ggcaatcaca gctattataa tcatcacgac cattgttaca atcatcatat ttatcatagc
    13021 cattgttgta atcattatca tcaaatggtc caaaatattt atttctactc attattaaaa
    13081 gcacctcctg atatatttga gcttttaagc tctatatata atatgtcaaa tttagtatga
    13141 ttgtgaccta tcaactattt ttaaatttac taaaataatt ttcattgtgc aaaacagcac
    13201 tatcgttagg tttgatttct tttgtttttt catgataata aatagcttta tctgattctc
    13261 ctaacctgtc ataacagaca cttaattgta tagatggtat atatccataa caatcatttg
    13321 acttaaaacc tccattagta tcattcttat ctcttgttaa tgctacctta taccaaaaaa
    13381 tggcttcttt atatttttgt ctatcaaaca tatgctttcc tatgtcacaa caaatttctg
    13441 ctcttggctc atcaaattcg aaacttctaa acaatgaata taatgcactt ttttcatcat
    13501 taattaagta ataacatgtg gctaaatctc tgcaagcact gatacaatcc tcaatccatc
    13561 ctcttgatga gtctaaaaac ttagtaaaac cttctattgc ttctttatac ctagcattat
    13621 agtacaactc tctagaataa tagaattggt gtcttggctc caatgttttt ccttctgaaa
    13681 tcattttttc aaaaattcta agatttctta gagggtcctg tctatgaagc tttttatgag
    13741 atattgcaat gtcagaataa aatacctctc caaaaagagg tactacttca tgaatagggt
    13801 caacccattt atgattagaa cttcttttaa acaatcgttc tctataatac gagagagttg
    13861 ggttaccatt ttcatcaaag gatacattgt attttgccat aacaatatca atggaagtat
    13921 ccaagctttc tttaatcttt aataattttt ctctatcagc ttctaaaatt atgtcatctg
    13981 catcaagcca catagtatag tctttagaag ctttagaaaa tgaaaaattt cttgcagcag
    14041 agaaatcatc tatccattcg aaatcgtaca ccatgtctgt atattttgag actatttctt
    14101 ttgtggaatc tgtagaaccg gtatctacaa ttataatttc gtctactata tcctttacac
    14161 attctaagca tctgcctata acttcttcct cattcttaac aatcatgcac aaacttattg
    14221 taatcataat gtacaactcc tttgtcttct atatattgca gacataagta atatatggta
    14281 ttttctcttg ttttgttatt aaatttataa aaacttttga cgacagaaag ttactaaaga
    14341 accttatctt ttatgtattt tttatagtag aatttattaa acttgaaatt tggtaataat
    14401 tgttgaaatg ataaaaccat atttaatttc atacaaaaaa gagtgtccca taaattaaaa
    14461 agttcatttt gagacactct tatttaatat tatatatata cttgtaaaac agacatttta
    14521 atatgatact ttgatacttt attcattcct attcattata taatcaatca gcccgtactc
    14581 tttagcctct agtgcagtca taaaattatc tctatctgta tctctcctaa tatcttctat
    14641 tgatttacct gtattttcag aaagaatttt atctaatcgt tcttttattt tcaatatatt
    14701 atctacagct atttttacat cagttgcttg acctttagct cctcccattg gctgatgaat
    14761 cataatctct gaattgggta aagcacatct ttttccatgt gttcctcctg caagtaaaaa
    14821 agcactcatg cttgcagcca taccaataca aatagtcgat acatcacatc tgacataatt
    14881 catagtatca tatatagcaa atcctgatgt agcagagcca ccagggctat ttatatatat
    14941 aattatatct gaatctgggt cttctgattc taaaaacagt aattgagcta ctactaaact
    15001 tgcaatagca tcattaattt cttctcctat aaatataatt ctatctttta ataattttga
    15061 atatatatca taagaccttt ccccttgacc tgtttgttca attacatgtg gcactaaact
    15121 catgctactt tcacctcaca attaatatta aagttcagat aagaattgat ttcatctctt
    15181 ctttgtttat aattcatatt tgcataagaa atacattttt cgctttgaat ttgatgattt
    15241 agatttaaaa caaatctctg ttgaatagga taaaattcat ctttatttct atatacttgt
    15301 ggagattctt tatataaatt tctaaatgct agtgtaaaag attgatgtgt agaatatcct
    15361 actgtaatag ctatgtctat aatatatttg tctgtaaata taagttgtct agctgcttca
    15421 gtaagtctcc tcctctgtat gtattgatgg atagtacatc ctacaacatt tgtaaacatt
    15481 ctgtgtaaat ggtattttga ataattagca atataagcta ttttatctaa atttagattt
    15541 tctgtaagat tttcttctat ataatcaatt atctccataa taacatctgt atttgttttc
    15601 aactctatcc tctcctttta agtattataa cctatgcaaa aagttttttc ttaatataaa
    15661 ttgctatctt aatttagtgt atagcaataa agtatcgata aaaaaatatc aggtattttt
    15721 atacaaaaat attaatatat atttctttta aagtttaaac ttaattacat ctattatatg
    15781 tagattgcta tatgttttat ctatgtacct tgattcatat gtattatttt gctgagtatt
    15841 tttacacctt tttcaatttc atcaaaacta agatgagcat aacctagtat aatttcatgg
    15901 tcatattcta atatattctc aattgcatat tgttgtatag gataaacttt tatacctgct
    15961 tcaaaaattt tatgaattaa actttccgta aatttaacat tatagaaatg agcaactata
    16021 tgaagccctg ctgcttcacc ttttatttta aattcatttt taaattccgt gtttaaaact
    16081 tttatgaggt acttacgttt tctattgtac aacttcttca ttctaaatat gtacttctct
    16141 aaacctccat ttccaataaa ttcagctaat acatgttgca atattgtttc tgtatgaaca
    16201 tcagagtaca tttttaaggt tttatagctt tctaaaatat tgtctggtaa taacataaat
    16261 ccaacacgaa tagctggaga taatatttta ctaaaagaac ctatgtaaat tactttattt
    16321 gggctaagtt cataaagaga actaattggt tgaccctcat atctaaattc actatcataa
    16381 tcatcttcaa ttatatagta atcattctct gttgcacatt taataagctc tagtcttctt
    16441 tgaataggta aaatccctcc taatgggtat tgatgagaag gtgtagtata aacaaaagaa
    16501 atccctttta ttgattttat taagttggta ttcattccct tatcatctac tttaattcca
    16561 acaactgaat atccaataga tgaaataacc tttaataagc ctttatgaat agggtcttct
    16621 acagcaacct ttttattact tttgtataaa agctgtgaaa ttaaagataa accttgtgtt
    16681 gaaccagaaa caatcataat gtttttggga ttacatctaa ttcctctagt acgaaataaa
    16741 tacttagata tttccactct taaaacccat acaccagctg tacttccata tctgaaatcc
    16801 gaatctgata aatcatacag tatttgttta tatagctttg aaaattcttt gcgtggaaat
    16861 agttttaatt ctggaactcc tgaacgaaaa tctatataat ttttttgttt attagtatgt
    16921 aaatcttttt catctctaaa agtatcattt aacttaaaat caactttatg ccctgatatt
    16981 cctttagcta caattgttcc atatccattc cttgtttcca aatatccttc tgcaattaat
    17041 tgattatatg catctaaaac tgtattacga gatacagata gttcttttga taaagtccta
    17101 gatgatggca gtttttgctc aaactttaag cttccatcca gaatcatatc ttttatctca
    17161 caataaattt gtcttgataa tgatatatta ctatttctat taatcgtaat ccacattcta
    17221 atacctccaa aagtggttct ataaaattac tataaaaatg gaactacaaa atccactttt
    17281 aatttgctaa gattatatca taaaatataa aataaaaagg agtctatatt atgttagaaa
    17341 tatcacataa agttaaagaa atttatccca atattaaatt tggagttatg gttataaata
    17401 ttacacattc aaaacctaat aaagaaaatt ttttagttct taaaaactct acaattaaaa
    17461 atattataga acaacaccca gaatacaatc gtaaagaaaa aattaaaaca gagcctgttt
    17521 caagttatat aaagtattat aaaaaattca agaaaactta ccctgtattg cttcaattag
    17581 aatctattct attaaaatca aaaggtatcc cagatgtagg tgtaacaatt gagtcaatgt
    17641 ttttagcaga attgaaaaat cttcttctaa cagcaggtca tgaccttgat aaaatggaat
    17701 tacctttgaa aatagaatta gcaaatggaa gtgaacattt ttatggtata ggtggtaaag
    17761 aacatatttt aacaaaagat gatttatttt tatcagataa tattggtata ttatctagta
    17821 ttcttaatgg ccctgataat cgaacagcta taacaaaaga tactaaaaat attatgtatt
    17881 ttgtatatgg acctgataaa atatcagaaa agcaaattca agaccattta aatgatataa
    17941 aacactatat ttcaagtgct tttccagatt tgaaagttaa ttcaattgat atattttagt
    18001 taatatatta aaatcctcat aaatattttg aataaataaa ttagtgaagt atacattcta
    18061 gttaaactag atatacttca ctaaaattaa ttatatgtag atattattta ttttgaattt
    18121 tgtttataat aaacacttta ttacatttat cctatgaata acttaatttt ataattaaag
    18181 agtttcataa gaaacaattt cacttaaagg aacacgagtt ttttcatgtc tctctgggct
    18241 ctctggtatc ttagattcat atcccatcaa taatatattt attggttcta gattatctgg
    18301 caaactaaac tcttctctaa ttatatctgg attaaaatag cacacccaaa cacttgccaa
    18361 tccaagttca gttgcctgta acatcatatg gtctgtaact atacttgtgt caatatctgt
    18421 aagttgtttc ccatcaaaag gtcttgtcca aactttgtct ttatctccac atacaagaat
    18481 tgctaatggc gcatcatata tattggcagc cttagaaagt ttatttatac cttctttttc
    18541 ctgaataaca atcaatcttt gaggttgacg attaccacca gttggagcta ttcttgcaac
    18601 atctaaaacc ttctcaagtt tttctttttc aacctttcta tcttgataat tacggcaaga
    18661 atatcttttt tttgcaagtt caacgaaatt catttattta ccccctattg ttttattagg
    18721 ctaagttgat gatttattta acctatgcta taattttatc actatggtac tatattacaa
    18781 taatgcactt ttttgtaata tagtacctaa aaagatactt taaaataaat aaaggagccc
    18841 aaaaatgaaa aaatgtttag ataattacag ttgcccaata gaagcaacac ttgcattgat
    18901 tggtggtaaa tataagacac ttatactttg gcatcttaaa gacactatat tgaggttcaa
    18961 tgaattaaaa aaattaattc ctaaagcaac gcctaagatg ttaactcaac aattacgtga
    19021 attagaatca gatggtttaa ttataagagt ggtttatcct gttgttcctc caaaagtaga
    19081 atactcgcta tctgattttg gaaagagtat tattccaatt ttagattcca tgtgtgactg
    19141 gggttctgat tacttagaaa atctataaac cattacagtt taaatcccat tgctaattta
    19201 acttcatcca tttgttcttt agatgtcaac atttctaaaa gcttaaaagc tacatgtgga
    19261 gctgtttctg gacaatatga ggttataata tttttatcta caacaattgg ttcattaact
    19321 acatttacat caaactcact taactgtctt tgtcttttac catttttcaa atgatatgta
    19381 gtagctttac gattttttaa aacaccactt tttccaactg gcaatgctgc cacacaaata
    19441 gaagcgatta ttttttcttt tgaattaaac tcccttatta gatttaaaaa agatgaatca
    19501 tatgcttcat cataaaatcc aaattcttca aatcctccag gaatagctag agcatcataa
    19561 tcatcaacac atacttcttc tatcgtctta tcaactaata cttgtatatt aaatgtgctc
    19621 ataacttgtt ttttaaatcc acaagtcact acatcaatat catgcccata atcgttacga
    19681 gcccatccca taacatctac aaatacacta aattccatag tttcaaaacc ttttgctaaa
    19741 aaaactaaaa ctttcatatt ctattttcct cctaaaatat aattaacact ttactagtaa
    19801 attatttaaa aaatatcttt tattgtatta aattcttctt taattgtaga taaaacaatg
    19861 gttgtattag ctttttgaat ccccccaatt tccttcaaag tcactgatat aaactcttca
    19921 agattacttg tatcttctgc taatactttt attaagtaat catactctcc tgaaatatga
    19981 tgacattcta atacagtatc atattccaat atagttttct taaattcttt catactttta
    20041 gataaatcag tattgataaa tataaaagcc aaaagcttat attttgtttt ttcccgatta
    20101 atttgaatag tgtacttttg aattaaattt gactgctcaa ttttccttat acgctctgag
    20161 actgctggta ctgataaatt aatttgtctg cttatttcag aggttgaagc cctactattc
    20221 ttttttagag aattaattat ttttaaatct atttcatcca gagctactca cctccttaat
    20281 tatttaatac aattttagct aataatttac attaagtaaa taaatttaat catttcaata
    20341 aaatttaata caaatatgtt atttttcctt aaaattttag ttttctttaa tcaaaacaca
    20401 tataatactt aaaattattt aagttgaatt aatgttttta ttttgtataa tatattagaa
    20461 ccttaatata tcattgaaaa ttcaacaata ctagacatat acttctacat gttgtaatat
    20521 ttatgaaaat agtatcccta tatcaaaatt ataaaactca taatcttaat tttcttatag
    20581 actataaaat tttattgata gcgagtcttc aaataacttt gtaatgatag atttactaaa
    20641 ttaatataat aatagtaaat ataactttct tattgactat aactaagtat tatgataaca
    20701 taacttaagc tataattaat aaaacgtatt ttaaataaat aagataatcc acaaagtaca
    20761 aaagtacaat ttaaatatag ataaactaga attaatacta agattaggat gtgaataatt
    20821 atgatttata tagaattagt taaacttgtt agaaaactta actctacaca aatgtatacg
    20881 atgaagcgtt gtgtagaggt taatctgaaa gcttaaagct ttctatcttc atcggcaaat
    20941 ataggtttag tatagttttt tggctatgct tatttaaaat tacctatttg ccgatagata
    21001 atatagattt tctggtcata gacaacaatg cttgtctatg accttttgtt tttccaaaag
    21061 cagaggtcgg cattttacaa tgccattcct ctgctttttt tatttccata aattttttaa
    21121 taaaagaaaa ggagtttgaa ttatgagttt attaaaagta actaatttat cacaatgttt
    21181 tatggataaa tcactgtatg agaaagctaa ctttgattta ttcaaaggtg aacatatagg
    21241 tgtagttggc caaaatggta caggtaaaag tacattaatt aaaattttat tgggagaagt
    21301 tgttccagat tcaggagaaa tcaagtggca acctaatatc aatataggcc atttagacca
    21361 atatgcagaa atcaatagag atacaacaat atcactctat ttacacactg catttgagga
    21421 actttataaa atagaaaagg aaatgaatct actctatcaa aaaagtgcta tatctgaaaa
    21481 tgggcaatat ctaatcaaag catcagatta tcaggaacaa ctaatagcaa ataatttcta
    21541 ttctatagat aatgaaataa ataaaatagc aaatggtctt ggattagatt caataggaat
    21601 gaatcgtgtt gttggagagc ttagtggtgg tcaaagggca aaggtaattt tagcaaaatt
    21661 actactttct aaccatgatg ttctattatt agacgaacca acaaactttt tagataaaga
    21721 acatgttgaa tggctctcaa attatttaaa tacatttaat ggggcattta ttgtagtttc
    21781 ccacgatttt gactttttag aaaaaatttc tacaggtatt cttgatatag aatttggcat
    21841 gattaagaaa tatcatggaa aatattcaga gttccttaaa caaaaatcac atttaagaga
    21901 agattatatt agaaggtatc aagcacaaca aaagaaaata gaaaaagaag aaacatttat
    21961 acgtaaaaat aaagctggag taaattcaaa aattgcaaga ggaagacaaa aacaattgga
    22021 taaaatagaa agaatagctc ctcctagttt tacaggaaaa ccaaatattc aattttcaga
    22081 aattgaaata tcggctcaaa atgctcttac tataacaaat cttgaagttg gatactacta
    22141 ttctttactt ccaaaattaa atttttctgt tgatggaggt caaaaaatag ttataactgg
    22201 ttttaatgga atcggtaaat ctaccttgtt aaagacatta gtaaaagata ttcctcgtat
    22261 atctggagat ttccagtttt cagaacaagt taaaattggt tattatgagc aagatttaaa
    22321 atgggaaaat cctgataaaa ccccacttca aatagtagca gataaatatc caaaattaaa
    22381 tacaaaagag attagacgtc atctagccag atgtggtgtg aaggaagagc atgtttcaag
    22441 gagtgtatct actttaagtg gtggtgaaca atctaaggtt aaattatgtt gtatgatgtt
    22501 atctccttgt aattttctta ttctggatga accaaccaat cactttgatg cagagacaaa
    22561 ggatgcttta caaaatgctt tgaaacagtt tagaggaagt ataatcctag tttcccatga
    22621 agaaaaattt tataaaggtt ggattgataa agtatttaat atagaaaaac aattagtata
    22681 agtttataca caatatacaa tattatttaa ttggtatttc aatgcaaatt ttaatgttct
    22741 agttaatgtt tcactgcaaa taaactaaaa aaattttatt agaacataaa gtacattacc
    22801 aggatataaa cttaatgagg ctatctcaaa atagagatag acctcttctt cattgttgag
    22861 ataacgaaaa tacatttgat ttcacccata aaagaatgcc tcattaacta aaaattcaac
    22921 ttgagatatc ttcattaata ttaaaatcta ttctaatcga ttctattcac aagtttatat
    22981 cctagtcctt taactgttat aagtatttta ggatttgagg ggttatcttc aattttttct
    23041 cttatatgtc gtatatgcac cataattgta ttgtcacaaa tactactata tactccccat
    23101 acttgttcat agagtctttc ttttcctata attttattta catttttagc catgtagctt
    23161 aaaagatgat actcccttcc agttaactca atctcatttc tatctttata tacacggttt
    23221 ccttctatat caatagtaat atctcctatt ttaataactt cactatctga tggtacaatg
    23281 ctttgatact gttgtctacg taattgcgct ttaactcgaa aagcaatttc tcttggactg
    23341 aatggctttg ttatatagtc atctccccca ctactaagac ctagtatttt gtcaatatca
    23401 tcattttttg atgataaaaa aagaatagaa cagtatgaaa actctcgaat ttttttacac
    23461 acttctatac catctatatc tggtaacatt atatcaagaa tgacaacatc tggacatgct
    23521 atcttacaca gcgaaatagc atctagacca ttataagctt taataatgtt tttaaaacca
    23581 tcatttatga gtacttcttc aattaaatct actatatcct tttcatcatc aacaagtaat
    23641 atttttttat taaaacatgt atccatattg aaatctctcc ataaaaattt attatattct
    23701 aatcttgcag tatcactatc ttgtttttta tattcactac tcttgctttt acattactaa
    23761 tagtaacatc tctaatagac aaattcaatc actatgaaaa ttaagataag tttctttaaa
    23821 ataaagtgta tgatacatta aaacctatag aaaattaatt tcatccaaag tttataatat
    23881 tagactaata cacttacaga tacagattaa tacaatagta aaataaaagg agttgtctta
    23941 aaattgactt tttctaatca aactttaagt tcaactccct tttaaacttt tatatgttat
    24001 ttttattaat tctttatatc aattataact ttaattttca atagtatata tctaccacta
    24061 attgaattac ttattaaaac ataaaatatc tatctaagct atttatttaa tatctacata
    24121 tatttatatc tattcttata cttaaatata caaaaaacag ttaaaaataa ggttaaaatc
    24181 tcagcacttg gtactgctaa ccatatccca tttatattta atatatttgg caatatcaat
    24241 aaacctatag ttataaatcc aaatgtacgt agaaaagata atattgcaga cacctttcca
    24301 tttgataatg ctgtaaacat agatgaggta aaaatattat atccacaaaa aataaaacta
    24361 aaagaaaata tataaaatcc ggaccttgca atttcataaa ctcggcttcc tctttgagaa
    24421 aaagtctcta caatgattgg tgaacatgat atagaaaaga taaataccaa taaagatgct
    24481 actgaaataa ataatataca aatcttaaaa acatgattta actgcgtatt attttcactt
    24541 ccatagttat aacttattat tggtgcaaca cccattgaga aacctatata aagcgaagtt
    24601 aaaagaaatt gagaataaat aattattgta atagctgcaa ccccatcttc accaattaat
    24661 ttcatcatca tagcattaaa taaaaaagta gtaactgctg ttgatagttg acccaccatt
    24721 tcagatgaac cattaaaaca agcttcaaat aatattcttt tatctagtct aggtatacaa
    24781 aatttaagta accctttatt ttttgaaaag aaaaccatac ctgaaatggt aggaattagg
    24841 tatcctactc cagttgcaag tgctgctcca ctaataccca tttgtaacag aacaatgaac
    24901 acatagtcaa gaattatatt agcacaccca gcacctaaca ctagccataa tccaaattga
    24961 ggctttccag ctgttacaaa taaacattga aataatactt gtagtatatt tgcagaagca
    25021 aaaaccaaga taataaaaag atatgaacga caatatttaa ttaaaacttc acttgctcct
    25081 aaccatataa tgatataatc cataaataca atacctatac cagtaattat taccccaatt
    25141 acaactcctg ataatacgat taaagaaaaa gctttatttg ctccctcaat atcaccattt
    25201 cctatcttac gtgctacaat agcacttcct ccagtggcaa gcatagttcc aattccaact
    25261 ataagattaa taattggaca tacaatatta attgctgata gagcatttgt attaataaat
    25321 cttgatacaa atatagtatc tacgattgta tacaacccca taaaaatcat cataaaaata
    25381 gtaggaaatg caaacttcaa tagagtaaat aaattaaatc tttgtgccag taaattatct
    25441 tgctcataaa gattatcttg ttcatgattt tctgaataat atacatcact cattttgttt
    25501 atttttctgt acattaatta tttttaaaat atattccaaa caattagaca tttacagacc
    25561 tcctttctgc ataagaatta tatctaatta tttggatata gttttaatta atcttgcttt
    25621 tttacacaat tatatttcta ctaaagaaac ttttaaattc ttactttaat aattttatag
    25681 ctttcagtgc ctttagcgca aatacttgtt cacatagttt agtgtcatat gaaacgtatt
    25741 tatatatagt tatacattgt ttatttttac taatttatta actacttgca cttttataat
    25801 gtctcatacc taacttccaa aatctccaca taaacaatgt aaacaaaaat acaattaaaa
    25861 ttgagtatat taatccatta attgttattg tcccagccaa aatttgagtc ggaattgtcg
    25921 acataattcc atatggtaag attaaataga ataatacttt aaaaacacct tcatatatta
    25981 caccaggaat tttcatattc attggcaata aattatcttc taatctcatt atcgcagaag
    26041 atgatataac aaaaaatgaa actgttctaa gtatgataca tacatcataa aaaagtaatg
    26101 tcatcaataa caccatgaaa atatatatta ttatcataac taaagttatc tctgagttta
    26161 actcagatat tccatataaa acaataagta tacttgctag aattaatggt gatgaaccaa
    26221 tattaatatt ttcaaatgtt aacctaaata gtggatctaa tggttttgta atatagtagt
    26281 ctaattctcc ttcttggatt tttcgtggaa tatcataaat accaaaaaag aaaatcgtca
    26341 tatttatcgc atttattaat gagaaagttc ctataaatat taacatctct ccttgttgcc
    26401 atccccctat tgagtctaca tgagaatata tactattaaa cattagaagt tgtaatataa
    26461 ataatgaact atctacaaaa aatgctccaa aaaaatcaaa tctaaatacc atcatctttg
    26521 ataatttcat ttttaataac ataaatatta ttttcaaatt ttttttcatc atatacccac
    26581 cccatcaaat aatgttctca ttcttttata cataacttta tttactacag aaaaaaataa
    26641 aacccataat gctagaataa ttaatccttg tattgcctca ttgctgtttc tacctattag
    26701 taacatagat ggcaaatatg ttgtataata aaatggaaat accttcataa ctgttactat
    26761 agtttctggt aagagtacaa gtggtatcat tgttcctgta ataaattcaa caatattttc
    26821 aattatcatt ctaaaaaaac taatctcaag aaatttaaat gacaaaatcc caataaagaa
    26881 gtggagtttc atcataaaaa taaaccctag aaaaatcatc aaaattgaaa ttaatatttg
    26941 aactggattt gatgtaaagg caaaatctat tttaaatata aaaatccata caaatgcaga
    27001 aatcatatta aatacaaaat aaaaacatgt cattccaaaa tttttagcaa taaaataatt
    27061 ttgaacatta attggaataa tcatgtactt tgaaaaggtg cccaatttta cacgattaca
    27121 tatctcttca ctggtactct ttgacatatc aatacctgct aaaaatgagc ttattatata
    27181 gtaagataac atagagttaa atgtaaaacc agagactatt ttattttcac caaaaattgc
    27241 tttccataaa atataagcaa ataaaatttt tacaatcgta aacaccatat taaccaccac
    27301 atcaaatctc cagataagtt gcactttaaa attaattttg gctacttcat aataccttct
    27361 aatactctgt ttaaatttat aaaacattga ataatttgaa cttgcttcat tatagttgct
    27421 cataatactc atcacttcct ttcttatata ttctctctac aatactacct atatcttctt
    27481 cttcaatcat tacatcttta acatcatatt tatcaaaaat ccatttaatc gtttcatttc
    27541 ctctttcttt tggcacaatt actgatatct tatgatttgt ttgttcaaca actttacaat
    27601 cttttggaaa tacaatgtta gtttcattgg aaaaactaac tgttattttt ttatattttt
    27661 gaaaatgatt aaatagtttc tctgtagaac catcatatat tttacggcta ttttctacaa
    27721 caatacttct actacagaga ctcttaatat cttccatgta atgagaagta agtataatag
    27781 tagttccttt tgtttcattt acttctttta ggaaatacct aatttgtttt tgggctatag
    27841 catctaagcc tatagttggt tcatccaaaa ataatatttt tggattatgt agaagggcta
    27901 ctattagttc cattttcatt ctttctccta aagaaagcgt cctaacttga acatttaaat
    27961 agtcagatac ctcaaataat tcgataaagt aatccaagtt ttttttatat tcttcattag
    28021 atatatcata taattcttta aataaaagaa acgtatctgc tggtgtcaat tcaaagaata
    28081 gttgactttt ttggcccata acaacagcat attgtttttt aaaattattt tctaatttgt
    28141 tagggtaata acccataaca gatatttctc cagaagacgg tacaataata ccagttaaca
    28201 tcttaataag agtagttttg ccagctccat tttgacctat taatccaaca aattctcctt
    28261 cttctatctt taaatcaaat gacgatatag ctgttttttc tgtatatttc ctattaaata
    28321 aagactttac actccccata aatcctgcct ttttctcaaa tcttctataa gatttagtca
    28381 gttcattaag ttcaattata ctcattttaa ctacctccat atttcataat ttatataaaa
    28441 aaagtccaca ggtatatatc tgcctttttc tgtgcttata tttaacagca caaaaacaga
    28501 aaactcctgt ggactagaaa aattaatact ctctatttca aaatagttat caaaataata
    28561 ctatacaaaa ttaataaaag tgtagcagat taaagcctac tacaccataa tttaacaaag
    28621 taatatatat tttaaatact atttgttgtc atatgtcagt tatctataaa ggcagaataa
    28681 gacacaaaaa ttaaatgtat taaaaataca cttaaaattt ctgattatac agaatatatg
    28741 tgtctccaac tatttaattg ttggttacca ttatataact ccgacatcaa ggcactcctc
    28801 tcataatatt attattgata tcatatcata aaggttattt atgttcaagt atggatttat
    28861 atactaatac atttagctta tttcttcagg gttgaattta aatttcattt ataatattcg
    28921 tttataaatt aaaaatataa tacgtatatt aaaactggtt attttactgt aatattttta
    28981 ttgtaaaaga tatactttta cctatacagg atgtaatttc tttagttcta tattataata
    29041 atattgtaat aagagttcaa cttataatac attaaaatat aaactgtaaa tcttaagggg
    29101 gtaatctatg gaaaataata caatacaaaa acaattaaga gatttatcaa aaaaaatttg
    29161 gcatatttat attttaaatc cagaagaaga aaaccttaaa tttattattt ccttattaga
    29221 tgacaacctt gcattaattg gaacaggaaa acatgaattt tacgaaacat tagaagaatt
    29281 tattataggt cttgaaaaag accaaacaga atcagagcaa atagactttg agattataga
    29341 tgagtggtat tcatgtacca aagttacaga cgaagctttt atagtatatg gtactctttg
    29401 ggtaatagaa aaagattacc tagaaaaaga tatctatgta gaaatggata ctcgatttac
    29461 tatggtatac agagttacag atgatatgat taaacttatc catgttcacc attctattcc
    29521 aaactttgac caaatgaaag atgagtatta ccctaaaaca ataactgaaa aagcacaaga
    29581 agcactagca atggcaaatg aatttaaact aaaatcagaa aaagacctta tgactggact
    29641 atacaataga catttttttg aagtacacat aaaagaaatg cttaaaactg tttcacatgg
    29701 atacttttac atctttgatt tagataattt taaacaggta aatgatatct ttggtcatgt
    29761 tcgaggagat gaaatactaa tacatttttc aaatattttg actaaagtat tcgtaaatga
    29821 tgctattatt ggaagacttg gtggagatga atttgctgtt tttgaatata gtaatcaatc
    29881 aaaagagaat gttgaaaata aggcaaagaa ggttttagaa ttatgcctag agagtaattc
    29941 ttgttctata ggtatatcta aattagaaaa taactctgat actttccagt ctttatacaa
    30001 acaatcggat tatgctttgt attattcaaa acgaaataat aaaggaaact ttagttggtt
    30061 ttagtacaaa agatattaaa ataggcaaat ttattagagt atcttgtcct atatactaat
    30121 aagtaaagta aacaacaagc tatctttgca tatatttata taaaccaact attcttaata
    30181 aaactacaat agtcaacatg accactatta tagaatataa taaactaaaa acattattaa
    30241 catgattaat attatatttt aataatttta tttttaaaag taagtccaaa atgttatatg
    30301 ttttgattaa aactgatgtt gatataaaaa attttactta aaaaaacact tagaaaggct
    30361 ttataaagag ccttttttgc ttttattgat taaattttca tataaaattc cttattaaat
    30421 ttcaaatcaa taaaaaaagg ctctataaga agcctcccct atttttattg attaaatcct
    30481 aatatagaca atgccttagc atcatagtaa gtagtcatct ctcttgttgc atcctttaat
    30541 ttacggtaat caaagtctaa tgatccacca aaagctgata tttcagaccc atcaaaccta
    30601 taccatttcc catcaatttg tatatagttc caagcatgat ttaatgacgg atttaatata
    30661 aatagtgaat tcattcccat taaccttgtt aataaatgaa agctacttgc aaaacttcca
    30721 catacaccac gtttatcaac cagattacca tagactatat tacaatattt agagtctgca
    30781 tattttgctt cggttaccaa ttttgcagct ctattagctc tttccatctc agatgcattt
    30841 ctccagtcaa aactatttaa aaaattcctg attactgtaa gtgtatcttg agcttgtttg
    30901 taagaaatcc aatttccatc ggctattact tctatagggt caagttttcc aaagcctatt
    30961 ctctgatatg agccacctga caatgctgcc gcataaaatc ctagcccttc cataccttta
    31021 tttatataat aatatttacc atctgctcga agctcaactc cattgggatt tcctccatag
    31081 agtaaatccc atccctcttt acctgttgta ttaagaccaa gttgtgttaa cattccttta
    31141 agaggatatt tagggtcata attagcacct ttacttattg catttgtttg cactctgcca
    31201 tccattgtgc ctatattagt ctgattacgt tcatttgcac tctgtttttt caagctagat
    31261 gtttcatctt cttgatatgg ctctgccatt actgtcatac tcatcatcaa tataataatc
    31321 atggtaatca tagtagttaa tatattcttc ttcatactac tcccccttat ttaattcttt
    31381 ttaaaacata aaattattaa ctcataaata tatggttatt agtaaattga aattaaatct
    31441 gattcataaa ttattggttt aatagaagtg tattgaaatt gtacctttat attttcatta
    31501 tataataaac ttattttttt aaaacatatt gtttaaatca gtacatttat atgttttttt
    31561 tgttcatctg ttttatcaaa tatattagtc tttgaatttt gtttgtattc ttcagcatct
    31621 ttatctaact tttctattct cgactcaagt ttcattattt cttcttgtgt taaatttata
    31681 aaatttttaa gcatattttc aagctcttca cgagttttac ctactaaaga taagtcctca
    31741 gatactttct cttttttatt ggaatcctct ttataatcct ttttttgttc taactcttct
    31801 aatttttcat catttaatat ttcttcttca attttttcat tagactcttt agtgattaaa
    31861 gattcttttt catcatttgt atttagataa gttgaatttt catctaacat tgtactttta
    31921 tttttatctt ctataatgct atttttaata cctatttcta tattagaaaa gttattagtt
    31981 gtttctctta tttctgattt acataagttc ttaattgcgt catttatttt tttagcataa
    32041 acctcttgtc tatattttaa atctctaatt ctatcattaa gttcttgctt ttgtttcata
    32101 atattagata aataagtgtc ttttcctaca gtttcatttt tcttaaccat attttcattt
    32161 attcttgtat tatttatatt actttcatat ctaaatgaat attgacttct atattgacta
    32221 gatattttca tttatttcac ctccctaaaa taaatttatg tttatagaaa ccaacttaac
    32281 ttaattatat tttatcatca aaagtataca tttacaaata ttagttaata gttttatagg
    32341 ttcgagcatt attttcaaca aaaaattttt attataaatt aaaacaataa tttttataaa
    32401 tatattattt gtattttata attcatatat ttttacttta taaattagca atattgcagt
    32461 tttgctctta agaaacatct ctatcataca taagcatata ctctattatg tattagtata
    32521 aatatgcctt ttcttatctt acataagacc tctttataaa gaagcctatc gtaacaaata
    32581 tgtatacatt atcacatgta tatatcatca tataaaaaat caaactttat taaaaaaatt
    32641 aataaattgc tttaaataat accacaaacc aaatttgcca tcaaaatcac attaaagtaa
    32701 caaattgatg gcaaatttaa tatattaata gtatatagac tcatagaatg aacaaaaaaa
    32761 ctacacttat cttctaatct tcttatttat ttttgagata tttttaaatt tcttttcttt
    32821 ttttgctaag tattcgcttt tattgtctgc aaatactgct tcagttttaa gcctacgata
    32881 ggattcccat cttttaggcg aaagttcttg atgagcaata gcttcccaga tagcacagcc
    32941 tggttctgag gtgtgagtac aattacgaaa atgacatttt ccgaaataag cttctatatc
    33001 tgcaaaactt ttatctaaac cttctgaaac atcccacatt cccaactctc tcatacctgg
    33061 tgtgtcaata acaataccac cacctgaaat taaaaatagc tctcgtctag tcgtggcatg
    33121 tcttccttta tcatcatcta tgcgaatttc ctttgtattt aaaaattctc cacccatcag
    33181 acaattaatt aatgaagatt ttccaactcc tgaagaacca agtaaggcaa cagtacagcc
    33241 tggtttaata tacttagaaa tctgtttata accatctggc tctatagatg aggtaacaac
    33301 tacatctaca cccaaggcta tagaattaac tacttgtaat ttacgatgca cattgtcaca
    33361 taagtctgat ttagtaagta ctactactgg gatagctcca ctttcccatg ttaaagacag
    33421 atacctctcc aatctatgaa tgttaaaatc cttattcagt gacatgcaca aaaaaacaat
    33481 gtcaatatta gctgcaacca cctgctcctc atttaccttt ccagcagcct tacgcacaaa
    33541 caagcttttt ctatgaagca catgatgaat aatagcatta ccatttttat tattgcaacg
    33601 atccaacata acgaaatcac caactgtggg aaaatcagat tgtatagtag cctcaaaacg
    33661 cagctttcct gaaacctctg caaacagtac accatttaca catacagctt gataaaagtt
    33721 cttttcctgc gagataatcc gagcaaggta taaatcatga tattccatac tttgagtaat
    33781 aaaatttcta tttagaccat agtcttgtaa attgatttgt ttcataccat tcattctgtt
    33841 tcctcctttt ccaacttttc aatgattctt tctagtggga aagggggctg tgccagtggt
    33901 tttaatgcaa ttgacattaa tttcactgaa ttatcatcag ctgcaatacg attagaacta
    33961 agatgtccac agcgtgtaca acgatgaata attgcccact caccattttt tctcacccac
    34021 actccaatag gttccatatt agcatcacaa tctgcagcac ggtcaccagg aatgatatct
    34081 acatgaagac tatgtaaaca atgtggacaa tgatttctat gttgtgtacc agctccttca
    34141 ggaactacaa gacaaccaca atttttgcaa ataaagttat ccatacagga attttcctga
    34201 taataagctc gttttctatt tttataattc atttttattt cctccgtatc ttgtattttc
    34261 tacaaaaaaa gtccacaggt atttatatct gcctttttat gtggtataca tatttaccta
    34321 cacaaaaaca gaaaacccct gtggactaga aaatttagta tcttctattt caacataatt
    34381 atattcaaaa taatactgtg taaaattaat aaaagtgtag cagattaaag cccactacac
    34441 cacaatttaa caaagtaata tgtaatatta ttatttgttg tctaatgtta gttatctata
    34501 aaggcagagt aagacacaac aatcaaatgt atcaaaaata cacttaaaaa ttctgattaa
    34561 acaggaccca tatgcgtctc caactattta tttgttggtt accattatat ataactctga
    34621 catcaggcaa gacactcctt cactaataat tattattgaa attttatcat aaaatataag
    34681 tatgttcaag tataatttaa tatattcata tatttatgtt tgtctcattt tcttattcta
    34741 taaaatctag tggtatttta aaatttaatg ttcacctagt attaataata aaaattaact
    34801 gctattattt gttttctcat tttatgcctg ttgctcaatt tatctcactt aaattaataa
    34861 caactgtctt ttcatacaaa acctacaatc aagtttttcc atatattcta catgcatagt
    34921 ctattttttt gatataaaat aacgttcata tttgtaaatt tatttaattt tcaaataagt
    34981 atattgaata ataagcaatt ctattgtatt attgtaattg tagaataaaa ctaaatcggc
    35041 aaaactagag aaatttagtg acgcaaagct atagggacta acgcttataa aataaactat
    35101 gagttatgtc agccagttgc caaaaagaga tattcttttt gtttttatga aagtttttta
    35161 gggggataat aatatatatg tttagagata aaatggatag atgtacacat atgttgactg
    35221 cttatattgg tagttcatat gattattgtg attttataga tacacaacta gatgatttta
    35281 tactagagta cggagaaaat gtggtagaat cttgtttgca tcaagtgatg gtattagtaa
    35341 gtaagtataa ttaaatagat ttggttttct agagaaccct ttttagtttt atctacttta
    35401 aatagcctta tgttagaaag ctaattaaga tagatttcta gtattcataa ttttattttt
    35461 tatttaaaat acatataata aagatgtaaa tttgtatcaa ataataaata tgagaactta
    35521 aattctctta tctatgtgaa aataaacatc tcttaaaatg aaattctgca aacataaatg
    35581 attttttagt ttgaaggatt agattaacaa aattataaat ttgcaaataa gctatattaa
    35641 aaaatataat aattttttat ataacttatt cttttataac ttttaatttt aaaagaggag
    35701 aatgtatata agagtattca atgtactaga aaaaatcaaa agaaatatta gaagaaatgg
    35761 atattgagta atcaaagaaa agattttgat attacaaatg atatgtttca agaaagcatt
    35821 cctatcacaa caaaaattat tcttgaagac atgccttcaa atgatgaatt aaatcatgtt
    35881 ttttcaaaag gttgtgaacg aaaaatgaaa aagagaaaaa ttgtattaat cacactacta
    35941 ttaatagatg ttttgttatt aggaagtatc ctatataatc tttttttagg aaaaacagct
    36001 aatatttcaa tgctaaagga atcttggaat tttgatatac caatacctaa caaagaaatt
    36061 gaagtatttg atactcaaga tagtattaat ggagatggac aaagttattt tattcaagga
    36121 ttttctgaaa aaaatttcaa aaaagttttt aatttaaaag gtggtatagt tgtaagcaaa
    36181 gataatatta atgaaataga aaaatatatt gataaattta aaagagattc tgttaacatt
    36241 aataaaagta ataaaaataa aattgaagaa gattttaaaa aatataagtt agaagttaaa
    36301 aaagatgata agtatatata taagagaaat tatgaaaact atgtagtttt aattataaaa
    36361 aaagatgaac aaaaattata cagtttaata tggaatcagt aggtacatat gtattattaa
    36421 gaattataaa taataaaaat aaattttagt caatatacaa aaacctttta aattgtttgg
    36481 aaatcacctc ctcatttgtt ataaaaacat acaacaaatg aagaggtgat tttatggttt
    36541 aaaaaaaaat aattataagt ggatatgtgc tttcacatgt ttatcaacat ttgtaatgcc
    36601 tatatttgct aatgaattat aatataaaaa tattaaataa tattcaacta tagattatgt
    36661 aaattattct atgaaaaaaa tgagttgtat aaaatctggc tactgtagat tgacgatttc
    36721 ttttaaaatt acaattataa taagttttat agaattaaaa ataaaacttt agagattttt
    36781 gataacattg tagactaaat ttgccaccaa aatcgcttta cagtggcaaa tcggtggcaa
    36841 atacaatata ttattagtat ataatctata taaacattac tattgtttga ttatcttagc
    36901 tacagtttcc acatgtgttg tcactaacat aggaacacac accttttacc tcgtctacga
    36961 tatgggaaca caattctttg gctttatcgc tcacactctt agacttgtcg aaacgctctt
    37021 ttgcctttcc aatttcattt ttaaaccctg ttttatatat gaaagtgatt ttatagggat
    37081 ctttgtttcc atcttcatca tagccaccga ctatgacttt ttcaattatg ctctcaaata
    37141 ttcctctgtc aaattcctcc aatacaccat tttttgataa tgccttttta aaatctgcca
    37201 ctcgctgctt taaagaaaat tcatcatcca tttgttgctc taaaatcttt aaattggctt
    37261 ttatatctga taatttcctc tcataaccta catctgtttc ttcgtaaata tcttgtgcaa
    37321 caattccttc gagataattt tccaacaatc tttttctttt agcttgaaga ttatctgcac
    37381 tcttttgtag ctttatgagt ttatctctta tggaatcctc actcaaagtc ttttctactc
    37441 tggaaataaa ttcttccagt acatccttgt tatctgcaca cagcatttta tacgattcga
    37501 taaatgcttc ctctattact tgttccggta ttcccttgct atccggacag aatctttttc
    37561 cgtcctttgt agatttaacg cattgccaaa tcgtcttttt atatttagaa ctgctatgcc
    37621 atcttcgcct tgataaattt gctccacaaa acccacattc caacagacag ctaaatgcat
    37681 attgtctgct atatttctct cgtttccccg gagtaaccga cttccttcct ccatttctcc
    37741 gctctcgaat ctcttgcgcc ctagcaaaag tttcggctga aataatgggt tcatggtggt
    37801 ctttgatata aaacctatct tcttctccaa gattttctaa tcttcttttt gaaatcggat
    37861 caacggtaaa cgtttttcct aatagtatat cgcctttata tttctcgtta ttgataattc
    37921 ccattacact ggaagatgtc caactattac ctcttatcgt tgtaatcccc tgttcattta
    37981 attctctggc aatcattgag cttcccgcac cagcaacata cctgtcaaat atatacctta
    38041 caacttctgc accttcttca tttatggaaa ttgattttgt tgcaacatcg taatcatatc
    38101 ctaaacaccc ctgaaatccg accaattctc cacgcttcat tttcattttt aatccctttt
    38161 ttacatatgc cgaggtattc tctacctcct gctgtgcaac agagcttaaa attgtcatta
    38221 aaaattcgcc atctttcaat gtatttatct tttcaacctc aaaataaact gcgatttttc
    38281 tttcttttaa catcctgaca tatttcaagg tatccaatgt atttcttgca aatcgaggta
    38341 agctcttggc aataaccata tcaatcttac catccataca gtcttgaatc agacgctgga
    38401 aatcttctct tttatcaact ttcgttcctg taatcgcttt atccgcatat acgcccgcaa
    38461 atacccactg ctcattattt tgtatcaatt cggtataatg cttgaccatc gaattataac
    38521 ttttaatctg atcctcatca tccgtactga cacgacaata tgctgcaact ctcaagcggt
    38581 ctacttttcg gactttggaa gattcatcga atggattgtt tgcctttata atttctactt
    38641 ccatatcttc ctcctttttt gtgttcctat cgtagtgttc gcttttatta taatgcaata
    38701 cagttcataa gtcaagctgt aatgttggac actatcccat aatcccgcat tagctttttt
    38761 tgaatctgct catactccaa ctcatttatt agcttcagat ttaatagttg ttttagcata
    38821 gataattgaa tgctatatct taatatcttc tttccttcca taagcaatca tcctttcgta
    38881 aatttccaaa tatcctccta tttccttgca cagccttatc tgctaataaa taggcagaat
    38941 acgcttctcc ccatttatta gcagataaaa actgcaatac aggtggcagc tcattacact
    39001 gcccacatcg gtcttgcacc gtcattttat tgaccggatt gcagactgct ctgcaatccg
    39061 gaagtatcat tattacagat atgcttcatc gccccatgta actgctacat attttgcccg
    39121 atctcactcg ctccttacct ttgcttcaat gtaccgtttc aacatttcct cacgttcacc
    39181 ccgtcataag acaaggcagg tacgtcatgg cgcatctgct tagtggctct gcatatcctc
    39241 acgtcctgta tgcaatacaa tattcaattt tcaaggtaca ccgctgataa tcagctatgg
    39301 aaaagggcag atagccgccc cttataccgc ttcaaacgcc agtatcttcg taatcagctt
    39361 tgtttcaagc ctccggcgca gcgtttcatc aacacaaaaa tgcagccgtc ctccctcgtc
    39421 atacattttc cgggtggaca gggtaattat gtatccctca taatgcttca ggactgtgtt
    39481 gattgccatt acatcgcctt ctgatgctgc ctttatgata tggaaaggca gcaaattctt
    39541 ttcttcgcta ttcttacatc tctttttcat ctgctttttc ctccataatc tttcttaaaa
    39601 tctcaaggga gcgtgtccgg tgttcgtgga tcgtactgcg tacaaggttc atttcccttg
    39661 ctatatccgc atcgctcatt tccagaaaat acgaaagcag tattacattc cgcttccgtt
    39721 ctgaaagtgc ctgcaatgct tccgcaatca gggtgtcttt cacttcaatg tcatatccat
    39781 gtactgtaaa atgactgttt tccactccat actcatccat aacaaacaac tggttcagct
    39841 ccttttcaga cagttcagaa aacatggctt catgctccct gcggtaatcc atgtgccggt
    39901 aatagttaat cgcttcacct ttcagcgaca tctgacacag gcggtcaaag cgatgtctga
    39961 ttgtcagttc atcatggcaa gaaggtttct tcatacgagt tcacctcctc ccccgttgtg
    40021 acgtgacaaa ggcatacgcc ttttcccttt ccgttgtatc tgccaaatgg cgataggctg
    40081 atgttcgggt gggagtaaaa attttatgta tataaaaaac gccctgacag gctgatgccc
    40141 gttggacgct attcatatct gttattctgt tttctccaca agctacgagt gcgtatagtt
    40201 cactctctaa ggtatattct gcttcacttc cagtaaagca ccttataaaa gaaccttccc
    40261 acgccaatag ccggacaggt tcccgaagtc aaaaaaatat ccctcagacc gttcagaaca
    40321 cataaattcc cctaaacgta cccaaaggat aaaatccacg caaaaaacct ctggatactg
    40381 cgttttttta tatgcaatat ccaaagttat tctatttcgt tgtgtgcatt atgcccctct
    40441 tataaagtga attattagta catttcaaaa gtaaaatgtg caatatacac tatacatgga
    40501 ggtgcatata tggcaagaaa aaagaaaatt gacaaggaaa tgggatttcg tctgaaacag
    40561 gctaggactg aacaaaaact gacctatgaa gaactggcag aaaaatccgg cgtttcctca
    40621 cgctatatca aggaaatcga aaatcatgga aacgtgccaa gccttgaaaa gctagggcag
    40681 ctcatacgag ccttacatat ttccgccgat ccgttttttt atccaactgt cccggcagac
    40741 aacctcgact accagcggct gttggtttat ctgtcacaat gtacagaaga acagattaca
    40801 acaattctcg ctattgtgga agcctatctt cggacatata aaaatttttc aaagtaaatc
    40861 cactccctct cctatctctt ttctaaaaca agggcggcta cccttagccg cctaattacc
    40921 tccttcctct gtaaaactgt ggctcgtttt gctgtacaga acgcttcttt ttaaggaagc
    40981 ggaatatgtc atcatttgtc atttcttctc aatgtaataa ctgcatggca tatcaagcca
    41041 aatacaagag aaaaacagcc tccgccaaat agtgatgctc cccaccctgc acccgacatt
    41101 gtcataaaac cgccaacaaa gaaaatacca atgccaagaa atataccaac accataaaaa
    41161 agtccaattg ccatatcgta cttattaaat tgtcgtttct cctttttttc atatgtttcc
    41221 atctttgtta ttacctcctt cgcaaaatcg tccatgtgga ctccaaaaag atagcaaatt
    41281 tttttcaatg tatttaaatc gggttcacta acatctctct cccaattcga tagcgcctgc
    41341 cgggtaacat tcaattcccc ggccagttct tcctgtgtca ttcccgattg tgttcgcaaa
    41401 tgacgtattt gctttcctgt tgtaatatcc gtctgttcct ggttcaaaat agttcctcct
    41461 ctctgatact gattttatca atgatatttc gcaatagcca gcaatgaaca cttgcattgc
    41521 gcaagacatt acattatctt ctgaaacata tggcgaacct tatctaaccg actatttggg
    41581 cggcaaggtt gtactacagg ttcctctgaa gtttcctgat accctttcaa ttctgccaag
    41641 caaacgcttc ttccatttgt atagaaattc aaatcacttt tatattcccc gatccgccga
    41701 gctggtattt ctccagttaa aattgcctca ttattttata acgaagttgt ttcaattacc
    41761 gcatcatatt tcacagcatc atgataagtt cgtgaaagat attcctgtgg cgcaaatagg
    41821 gtaaaagaaa gatagggttc taaaacttgt gttcccgctt ttttatacct gttccaacac
    41881 aacaggcgca agaaggcgga aatctgccgg agtactgacc gggccgtaat aaacaccata
    41941 ttcaaagctg aaccaaagac caaaaaataa gcattgtggg aaaatttaaa cttttggatt
    42001 ttcctacaat gccgactacg gcggaatccc tcccactcct tatacctttc tttccgtata
    42061 cattgaattt gtatttagta actgctataa tgtccctatt caaattaaaa atgtgttgaa
    42121 ttagttacat gtacatattt tttgtaccgg aggaagtgaa atgaatccaa aaatttatct
    42181 cattacaggc ttaatggctt ctggaaaatc tacagtttcc gatttactgg caaaatcaat
    42241 agaaaaatgc gtccatcttc gtggtgatgt gttccgaaaa atgattattt caggcagaga
    42301 aaatatgtca gctaccccat cagcggaagc agtccgccag ctgtaccttc gatacaaatt
    42361 gactgctgat gcggcaaagt catactttga taacggcttt tctgtagtga tccaagataa
    42421 ctactacggt gatgaattaa accgaatgat aaattatctg cataaatacc ctgttgaggt
    42481 tatcgttctt tgtccagatg tggaaacaat aaaagaaagg gaacgataca gggagaaaac
    42541 aggctattcc ggctttacgg tcgaaacctt atacgataca tttatgcaga caacaccacg
    42601 gatcggcttt tggctggaca attccaacca aacaccacag cagacagcag aaaccattct
    42661 gaacgccaga aagtcggtat gattgttaca tataagggga agaaaaattt cttttaggta
    42721 ctttctttcc taaaactaat gtgatataat agcatcattc caaaaaagga gtaaaaaata
    42781 tgcggcaagg tattcttaaa taaaactata gtaaaagtat tttactgctg gggattttta
    42841 tgcccttttg gggctgtaaa aggaggacaa tcacatgaaa ataatcaata ttggaattct
    42901 cgcccatgta gacgcaggaa aaacaacatt gacggaaagc ctgctgtaca ccagtggagc
    42961 gattgcggaa caaggaaacg tggataaagg aactacaaga acagacacta tgattttgga
    43021 acggcaacgg ggaattacta ttcagacagc ggttacttct ttttgctgga atgattataa
    43081 aatcaatatt gtggacactc ccggccatat ggatttttta accgaagcat accgctcttt
    43141 atctgtcctt gacggagctg ttttagtcat ttcggcaaaa gacggcgtac aggcacaaac
    43201 ccgtatatta ttccatgcgc ttcagaaaat ggacatcccg acaattatct ttataaataa
    43261 gatagaccaa aatgggatcg acctgcggcg tgtttaccaa agcattaaag ataaacttac
    43321 cagtgatatg attgtcatgc aggaggtttc cctgtcgcca aagataacca tgaccgatat
    43381 ttctgatttg gacaaatggg atatgattat ttccggaagc gatgaactat tagaacgata
    43441 tgttgcagag gattctttgg atatacagga attacaatat gaaaagtgca aaagaaccag
    43501 atgctgctct ttgtttcctg tttatcatgg gagtgcaaaa gacaatttag gaacagaaaa
    43561 actgattgaa gcgattacag aaactttcat tacagaaaca gacgatattc agtctgaatt
    43621 atgtggatat gtttttaagg ttgagtatac agagcggaaa aaacggcttt cttatttacg
    43681 cctgtatcat gggacgctcc atttacggga taccctgctg ctgtcaaaaa aggaaaaaat
    43741 aaagattaca gaaatgtgta ttccgtcaaa tggtgaaatc gtcccggttg accatgcctg
    43801 tccgggagaa attgttattt tagctgatga tactttgaaa ctgaacgaca ttctgggaaa
    43861 tgaaaaactc ctgcctcaca aaacacggat tgataatccc atgccattac ttcggacaac
    43921 ggtagagccg caaaagccgg agcaaaggga agccctgtta aatgccctcg cagagattgc
    43981 tgatacagac cctcttttgc attttgacat tgatactgtt acacatgaga ttatattatc
    44041 ttttttggga aaagtacagt tagaagttat ttgttcgcta ttagaagaaa aatatcatgt
    44101 gggcgtggct atgaaagagc cttcggttat ttatctggaa agaccgcaaa aaaaagcgag
    44161 ctgcacgatt catattgaag tgccgccgaa tccgttttgg gcatctattg gtctgactgt
    44221 aacaccgctt cctgttggaa gcggaacaca atataaaagc gaggtatctc tcggctattt
    44281 aaaccaaagt tttcaaaatg ccgtcatgga gggtgtgcgt tatggaatgg agcagggctt
    44341 atatggctgg ggagtgacag actgccaaat ttgttttgat tatggagttt attacagccc
    44401 ggtcagcacc cccgctgatt ttcgttttct tgcgcctgtc gtgttggagc aggcattgaa
    44461 aaaagcagga acacaactgt tggaaccata cctttccttt accctttttg caccgcagga
    44521 atatctttca cgggcttata atgacgcacc aaagtattgc gcaatcattg aatcaaccag
    44581 acttgaaaaa gatgaagtta tttttaaggg ggaaatccct gcccgttgta tcggtgaata
    44641 tagaaatgat ttgaattttt atacaaatgg aagaagtgtc tgcattacag aattaaaagg
    44701 gtatcaggaa acttccggcg agcctgtgtt tcagccacgc cgcccgaaca gccgtttaga
    44761 caagatccgg catatgtttc agaagataat gtaacatctt gcgcaatgca aacgttcatt
    44821 gctggctatt gcgaaatatc attgataaaa tcagcatcag agaggaggaa ctattttgaa
    44881 ccagaaacag acggatatta caacaggaaa acaaatacgt catctgcgga cacaatcggg
    44941 aatgacacag gaagaactgg ccggggaatt gaatgttacc cggcaggcgc tatcgaattg
    45001 ggagagagat gttaatgaac ccgatttaaa tacattgaaa aaaatttgtt ttctttttgg
    45061 cgtccacatg gacgattttg cgaaggagat aataacaaaa atggaaacat gtgaaaaaaa
    45121 ggagaaacga caatttaata agtatgatat ggcaattgga cttttttatg gtgtcgggat
    45181 atttcttggc attggtattt tctttgttgg cggttttatg acaatgtcgg gtgcagggtg
    45241 gggagcatca ctatttggcg gtggctgttt ttctcttgta tttggcttgc tatgccatgc
    45301 ggtaattaca ttgagaagaa gtgacaaatg atgacatatc ctgctttctg gacttttcgg
    45361 tcatatcgca aaaaaagccg ctgcttttgg ctttccaata gcggcggctt aatgcaagcg
    45421 gcggcaaagg gaaatatcct ttgcatacct tacagaagaa aagttttgca gcattacaaa
    45481 aataaaagcc tataccattt tggaaagaaa agatacataa tagtcaagac agcaacaatc
    45541 agaagttatg gagggtaaca atggaatata gtaaggaaga tttaatggaa gcaaaacggc
    45601 aaattgattc aacattgcat aaattgcggg aaaccataat aacctttgaa gcaaaagaaa
    45661 ctccagagag atataagtca cagattactt tggcgaaaag acggataagg gcttttgaaa
    45721 tagcaaatta ttttatagaa aacgagattg aaaacagtca gtaaattcaa aacaagtgta
    45781 tctttggcgt tggcattcgt tttgaatgct gtaatattaa tcgaaagaac cataatctga
    45841 aaaggaaggg gagtatccca aagtttgtgt aaaccttcaa attgatgtaa gatagactta
    45901 ccagtttgga ggtttatttt atggcaagga aaaaggatac accacaaaaa gcagcccttc
    45961 gggaaatgat gggcaactat ctgaaagaga acaatgtaaa ggtcaaggat ggaacggatg
    46021 tcaattccat tatgcgggat atgatgtcca tcattttgga aggtgccctg gagcaggaaa
    46081 tggatgagga actgggatat tccaagtatg attatcgaaa caaggaaaca gataattcca
    46141 gaaatggcca ttcccagaag accatgcata ccagctacgg cgatatggag attgatatcc
    46201 caagagaccg gaaaggggag tttgaaccac agatcgtcaa aaagtatcag aatacggtca
    46261 ctcaagacat ggaagaaaag atcatctcca tgtatgccaa aggaatgacc acgaatgata
    46321 tcgaaagcca tatgcgggaa ctctatgaca tcgagatttc tgacagcacc atcagcagga
    46381 tcacggataa aatcctgccc atcgtaaaag aatggcagga acggcctttg gaggaaatct
    46441 atgcggtcgt tttcatggac gccatccatt accatgtccg taatgaaggc aggattgtaa
    46501 aacgtgcggt ttatatcgct atcggaatcg atatggaagg gcataaagac gtgctcggca
    46561 tgtatgtagg gcaaaatgag agtgcaaagt tctggctttc cattttgaac ggactgaaga
    46621 accgtggcgt agaagatatc ctgatcgcat gcgtagacgg cctgacaggc tttccccagg
    46681 cgattgaagc cgttttcccg gatacggaga tccaacagtg tatcattcat caaatccgga
    46741 atacgacaaa gtttgtttcc tacaaggaac tcaagccgtt gatggctgat ctgaaacgtg
    46801 tatatgcagc cccaacggaa gaaatcgcac gggctgaact ggatggcttt gatgagaaat
    46861 ggagcgggaa atatcccaaa atcgcaaaat catggaaaga cagctgggca aatctttcaa
    46921 cgtatttcaa gtatccggaa gcggtccgcc gcttaatcta taccacgaat accatcgagg
    46981 gatttaaccg gcagctgagg aaggtcacga aatctaagac ggtattccct tcggatgaga
    47041 gtctcctgaa aatgctgtat ctggccatgg tggatatcac gaaaaaatgg actggacacc
    47101 gacaggattg gggacagatc cattcgcagc tggaaatatt ttttgaagaa cgattatccg
    47161 gattataagc tgtttctggt ctttcagggc tggcccagcc agccctgctt gacatgtctg
    47221 gaaactgcat tataatacaa gcaagggcag aacctcaaaa aatcggctct gcccagagta
    47281 actaatgaca tatcttatat cagttttttg agtttacaca aaacttgaaa cggtctcaaa
    47341 ggaagataat atttaaaaaa cattaaggaa aatttggcta ctccccatac tggcttttgc
    47401 taaacaactc caaccagtca ccccagcaga cagtaacctc cattttgaaa ctggaataaa
    47461 tttatcgatc atcacaattc caatctcatg gaaatgactt cctgaaatcc gactatgcgg
    47521 gagcgaaatc ctttgggatt tcttccacac tcaacaaatc cagcccgttc atacatagaa
    47581 actgctcttt cattttcagc aactacttta agttcaagct ggttatatcc cgctgtttta
    47641 gcacattcga tacacgaagc cagcaaagcc ttaccaattc caagtcccca atactttttc
    47701 acaacactga tgccaaattc tgctcgatgc cgtaccttat attttgtacc gattgcctca
    47761 attcctgctg ttcccgcaat tacactgtca actatggcaa gcaattcaat ctctctttca
    47821 ctctcagctt tttctttcag aaactggctc tcctgttcga cattaaaact gttttcatct
    47881 ggatatgtaa gcaaataatc tgtttcacta tgtgtcagat tgaaattatc cactacaagc
    47941 tgaccatcac tctctgttcc attcctcaaa caacattcca tgccattact taatattatt
    48001 gttttgttat atctcataac tgctccttta ctgacaactg tcctcaaagt cagcttcttc
    48061 atctatacaa tatcctaatc agaaaaatgt tttctcattt catattgttt aacaaataca
    48121 ctaaatttca atttcttcaa aaaagcgttc aatgcctgat cccgttcatc cacatttatt
    48181 accctcatct ctaaactctt tgtttgttta agtaaatcta acaaaatctc tgtggcaact
    48241 cccattctgc gatattgggg atgtaccgct aactgcgcaa tatctccttt tattttgtcc
    48301 acaataccat atccaatcaa gtttccatca aatttaacaa tcgtataaga aaaggattta
    48361 gcgattgcac aaacagcatc ttttgcgttt tgccatgaag gtggataagt ccaaaaatct
    48421 ttgaccgctg tccattgatc atcttgtaat ttttccggat gttccagttt ccacacttta
    48481 tgtacgcccg gttcttttat cttgcccgtc agttggtaac aattcaatat tctgttaatt
    48541 cgaaatccct gttttttata taaagtgagc gccttctcat tatcttgaat cacttccagt
    48601 tgatacatgc tgattttatt ttttatacat atagtgctaa ccagattcaa taattccccc
    48661 ataattcctg ttctccgaaa atcggggata actcctgttc cgaggtcata gactgtcttt
    48721 tcgttatccc aatctctcac tccattcaag ataaaaccga caagcgttct atctgcaaag
    48781 gctccaactg aaaccgcagg cataaatcca tttcttttca gcattgtttc aaaagattta
    48841 aaaggcatat caactgaaac ctgataatca gaaaatgcct gtgtaaacgc ttcgtatata
    48901 caaacggaat ctgtattttc caatgtccgg tattccatat tttctcctta atgctatatt
    48961 tactctattg gaagattgtg ctgtttcaaa aatgaaagct tatcccaata gcctcgttgg
    49021 aataaaattt tcccattcac tacctgaaaa aaaccacacc cccgtaaccc caatggatca
    49081 cgccattcca agattgccca ttgcccatcc tcaaaaatat tttccacgat agctgtcata
    49141 tccgctgttg aaaattcggc tgtgaacatg gtacggattg cttcaattcc tactactggt
    49201 tcattcgcta cttggtgatt cgtcgcattt tcatgataaa gggctgtaat tgcttccaca
    49261 tcatgtttat tgaatgcatc tacccataac tgaacaactt ctttcggtct taacatttct
    49321 gtttttcctc ctatgccttg tgtgttttta ttatatcaaa aagcaagttg aaagtcgaga
    49381 atcattataa aggcacaaaa actccacaaa ccaacacacc ctccgggagt gtcgagggta
    49441 gaatagcaag cactgcctat gtccggacac ataggcgaaa ttccccatac ttccctaccg
    49501 tccgtatgat gaaattacca tagggaagta tccctaaccc tctttgattt tctttctgct
    49561 ttttccctgc cagtccttga acattttccg cagatttgct ataataacac atggataatt
    49621 ctatccaaaa acaactgaac agacacgaaa ccagactgtt gtaaaccgag cattttacag
    49681 cagttttttt gtacccaaaa acaggaaagg aagtatcaga aatggcaaac aggacacgca
    49741 ccaaccggaa tgaatttcat ttagacgata aagagcagtt tatccttgat gagaagttta
    49801 agctgtccgg catgaaaagc aaatcagctt ttctccggaa acttatcctc tacggatatg
    49861 tctatgatgt tgattacagt ttcctccggg agtacaacac agagcttgga cggatcagct
    49921 ccagcctgaa ccagattgcg aaaagaatta acagtacaaa ccatgtctat caggaagata
    49981 tggacgaagt aaaggagttg atgaaacagg tatggcatac acaaaaatcc atgctatcac
    50041 agcaaccgtt gataaagcgg tagcctacat ctgtaacccg gataagactg atgaaagcat
    50101 ctacatttcc tcttatgcct gtgcgccgga aaccgcagcg attgacttca aatatacctt
    50161 agaccactgc cgggaaaaca gcccgaataa agcctatcat ctgatacagg ctttcgctcc
    50221 cggagaggtc agttttgaag aagcgcacca gatagggaaa gagcttgccg acaaagtttt
    50281 agaagggaaa tattcttacg ttgtcaccac acatattgat aaaggtcacg tccataacca
    50341 catcattttt tgtgctgccg acaaccttga acataacaaa taccacgact gtaaacagac
    50401 ctattaccgc atccgaaaat taagcgatga gctgtgcagc gagcataacc tttccgtcat
    50461 tatccccggc ggggagcgtg gcaaaaaata taacgaatgg cagtcagaca aaaacggtgc
    50521 cgcatggaaa acacagataa gaaaggacat caatgctgcc ataaaatcat cctccactta
    50581 tgaggaattt ctactcctga tgcgggcaaa aggctatgaa ataaaagggg aaagttctgg
    50641 ggaagatgcg ccaaaatata tctcattccg tccgcttgga aaagaccgtt ttgtacgtgg
    50701 cagtgtgaag tcactcggca gggaatacac aaaagaacgc atcaaagaac ggattgaatt
    50761 gaaacgggag cggaaagctg ttatcccgaa aaaagattac gcaggcaaaa gactggttga
    50821 cacctctgat gaaaaattcc agaacagtcc gggactgcaa aggtgggcag cgattgaaaa
    50881 tttaaagata gctgcacagg cttacaacga agccggttct attaaggaac tggaacaaaa
    50941 aatagccacc atagccgcca ccgggaagga agcaaaacag actgtccgta agttagaaaa
    51001 ccgcatcaaa gaccttgcgg aaatcatcaa gtatgcagaa cagtataagg caaataaatc
    51061 ctataacatc gcctacaaaa aagctaaaaa ccccgatgca tatttccgta agcatgagag
    51121 ccagatcatt ctctatggcg gcgcaaggcg tatgctggag caggcgggca tcagtctaaa
    51181 aggcttgaac attgacaagc tgaaagctga atatcaggag ctgaccgcac agaagaaaga
    51241 actggctgcc acctacaaaa actgtgataa ggaactgaaa acgctgaacc ggaaacttga
    51301 aaatctcaac cagtatttag ggcgctcaga gccgctaaaa gacgcaccaa aagagccaga
    51361 caggaataac acccctgccc ggtaaaaagg gcggagaatc gcctgttaaa agccaaaaaa
    51421 agcactgtgg aaatgtgcat aactccccat tccgtcatgg acaacaccgt tcacaggaca
    51481 tggaaaagca aaatgcagct ttcccacatc ctgcaaacaa tgttgcccac aactccatga
    51541 gaaggggagt tatacacatt acgcacagtg ccgacgcctg ctgaatccca ccctttcctt
    51601 cctgcctttt tatatgattc gtaaaaatct cttgcaggca aggctctttt cctgtaatat
    51661 agtcaacaaa tccgcaaaaa aataggagtg ccgaagcacc cccacttcct aaaccctctt
    51721 gcaaaatctg cagtgttggt ttataatcat catagaagcc gaaggattct agcacgtccg
    51781 acggttgtac aatcggaaac gagtaatcaa ttttagaaaa acaaacggat cactggctat
    51841 cccctattcg cagtagagaa tagccttttc cgttacttgc ggttgtgttt attgtctatg
    51901 tatgtcaagg ctgcaaaaat caccagcacc aacgtaagca cttctaacgt attcataccg
    51961 acctcctttc cgtttccaga aaggacaacc gcagactatc cctacctgct ctaatctgac
    52021 taaaaagaat tatagcactt cctgtcgaat aatgctataa aagtttcacg ataaattatt
    52081 ctgccgcttc cagttcaatc tccgcaaatt cctcatcgct catagtttcc agtttcccta
    52141 agacctgccc ggcaagctcc accatttcgc tgtcctgtat gtggggaatc acattcttta
    52201 tgtcggcaat catgcccctt ctgtcctgcc cctcaaacac acacatcaga ttgacttctt
    52261 ccactgtaaa tttatccata gctcatatct ccctctctga ttttttctcc gtcccctttt
    52321 ccggagcttc ttttcctgac ttatccctct gctcgatgac tgcctttttc tccgccagtt
    52381 tttcctttat ggaaaccctg cccgccttgt gttctttttc ctcttttggc ttctcattgt
    52441 tcaggacgtt atcaatcatg ttatagttac attcttccag ttcctcaatc ttcgcaagcg
    52501 gcttatactc tgccagtttg tctaaaagct cctttgcctt ccttgcagtc tgtacaccct
    52561 cactatcatc aagctccgtc cctttcccga ataaatccgt tatgccctcc ctcatgctgt
    52621 ctgaaatcat ggcattgagg aaatcattca gatactccgt attcccgttc ctgatgtcct
    52681 ctgcgatatt tgctacctgt gcttccctgt ccttcaccgt atcattgtac tgataagtgt
    52741 catagtcata ggaaagctgg tctatttctg cggcaaggaa agccgcctgc cacttttcca
    52801 gtgagccaag cacttcaata tccggcagct tgtcgatcag ctccgcaatt accgctaccg
    52861 ctttgggatt gtctgtaatg tccggcacat aatctaaaat ctccagatcg gcagtcctgc
    52921 ccgacacaat atccatctgt gtgtcctcat acgcttccgt tccttccgta tgaatgttga
    52981 tgccgatgct ccggatacca ttcatcctct ccggcggtat ctggttgaaa atttcgattg
    53041 cttcctccac gcttgctata tcctcatggt attctccgag gttatggaac tccccacact
    53101 ctgccactgt aagggtaatc actgtctgct tttcttcctg tgcctgttct gtattcctct
    53161 cctgcagggc agcacgtctt tccgcaaggt acgattctac ccccggaaga tactgcccaa
    53221 gcgtcccggt ctttccttct gtgatagggt tgatgtcaac tttcacgccg ccaatgctta
    53281 acccgtcctc attaaatgtg ttaaacagga aatcctccgt ttccccgccc cggtattcca
    53341 caaccacatc aaggtcagaa ttgtcctgtt ccagacctct gcacctgctc ccggacaccg
    53401 ccacatccac aagctctatg tccatatcat actcgtcaat cttggactgc aaataggcgt
    53461 atatggtaag ttctatatcc tcctgtgtct gcccattgat gccattccat aattcctctg
    53521 tccgggcttt aaaatcagct acaaccttgc tttccgccgc ttccggcact tcatttctga
    53581 tacgttcctc cagatgcgcc atttccgcct gctctgcctt ttccatcaat ccgtcataat
    53641 caatcggtat cagttcatca tccgcctgta tgttgccttc caaagcgctc cggtgcgccg
    53701 gctctttcaa atccgccaca atctcatcaa gtgcctgtct gattgttata tccggattgt
    53761 catacacccc accgtccaat ttccagtaac ccatatcgta aattgtgtag tcataccctt
    53821 cactggcttc ctgaatactg atatagcggt ctgccaactg gaaagcaagc tctgtttctt
    53881 ccctgccact ggcatctatg tacggattct tccattccgt aaaagggata ttttcaagga
    53941 tatggttttg ctccccctct ggcatcagat ttcccatttt cccctgttca tagagaatat
    54001 caaacctgtc catatacatt gaaacatcat ttatgccgct ggtctttagc tgaaactcaa
    54061 acagttcttt tactaaatct tttgtttcct ccggcgttct ctcccggtaa acctctgccc
    54121 ggtcaaaacc gacctcttga tataaagtct gcaaatcact cttgaaccga ctgttttcca
    54181 cttcattctg cgtaaattca agcggcacac agttccggtt atttttcaca tggagaacat
    54241 caaattcctt tccattgata ccaaatccaa atactgcctt tgtcatgcct gtctgatcag
    54301 aatcttccct ctcccggcac tccttaaact ttgtgattgc ttccacaaga ctgtcaaatc
    54361 gctctacctc gcctttttcc ggattactgc ctacccctgc agataaatcc tcaatgacat
    54421 agtaggtaaa tttatccgca tccgcttctt cctgtatgcc gctttctgcg gtattttccg
    54481 ccacttctgc cacatcctct atatctgtat ttttttcttc tctggtttct gaaaataccg
    54541 aaagttcttt cgtaaactct ggtatctccc tgtaaccaac agcatccaca taatggcttg
    54601 tattctcccc gtcctgatgc agcactacta tatcactgac cgaaagggaa tgtccggtaa
    54661 aatccaccgg acggtctata ttgaaccggg tataaatatc ttcaaggctc atgccctcct
    54721 tcagctcccc ggtgtagacc agagtgtaat tctctttaga aaccgggata cctttcatct
    54781 caagatagtc cattgccata aaacgaaaat cccttgtttc ctccgtatct ttaagctgat
    54841 agataccaaa cctgctctca tttccataca gaagccgcat ttccgggctt ggtgcatctt
    54901 cctctaatcc ctgttccaga taagcactcc aatcgtcctg ttccacgcca aacagaccgt
    54961 catgcccctg cactgcgccc caatcttcag caagcgtttc cgaaccgtct gaatggagca
    55021 gatatacctc cataccttcc tcaaacagtt ctgatgcccg ctcttttgtc agcggcagca
    55081 tttcattcca aagatagcca tactcgtgca tctccgataa acctaccatg ccatccggaa
    55141 gggcatctat ctccgcctgt gccacttcct ttgtttctaa cagcagaggt aaatcgtctt
    55201 tctgctccgc aagggaatat gcaagggaag tggttttctc catatcatcc agtttaaacg
    55261 catggttcat aatcaggttg cgctcgtcag tgccatatac cgacctgtgg aactccatga
    55321 ggttaatgag ctgctctgcc cgctgcatga ttggaagctc cgaagcagca tgaatctcct
    55381 ttttgcccat atctacctca aaatcataaa actgcggata accgtcattt accccaccgc
    55441 ttttcataat tgttacacat tcaaagcctt tttctttcag atagtccgta acactcccac
    55501 cccactcatt tccttcgccg ggcagcatat catataaggc attttccact tctgactgca
    55561 tatttatgat tttaatggtt tcatactccc cgttttcggg catggctatc cggacaacaa
    55621 catcggcata ttcaatcggc ttgttagctc tctcccgttc ttcctgcaat gccttaaaat
    55681 cggttatctc ataagtatcc gtattgtaag cgtaatctaa gtggtattcc tccacttcct
    55741 cgctccgttc attcccaagc agtgttaccc acgccccggc tctttcaagg taggcttcca
    55801 cgctctgcct gtcatcatct ttcatatcat gcagggaatt aaaaagctct gtccgttcca
    55861 tgcccctaac gctcaaaagg tcatattctg aacggtctgt attcgccaca agcagaatga
    55921 tgtcctcctg tgcctgttct gcagcacgtt ctttatcaat ctccaaaagc tgtgcttcaa
    55981 tcccctttat cagctccgag gaagtccggc gtatcgtatc aagggaagat tttaactccg
    56041 gcatttcctt cccgctgctc cactcggcga tatacccaaa agaatagtcg gacgtgtcaa
    56101 tcccgaaatg ctggcagacg gtataggcga tgctctcggc ttccacttcc tttgtttccc
    56161 tgtctttggc aatccctgtt tcctgttcaa cctcctttgc atggagtttt gcgtgtgcta
    56221 cctcatgtac cccggttttt gcagtctgcg cttctcccat gccctccttg atagcgatag
    56281 ggtggtttaa atcaataaaa tagcctttcc tgtcaccttc catgccctca tagcggattg
    56341 gtacagggga aacccttgca agtgcttcca taaaatcccg gtaacgctct acattccctt
    56401 gcagctcgct cacgccaagt ccgggaagct ctttcccgtc cgtctgtgaa tagtcaaaca
    56461 ctgtgacaac ccggaaagca ggtatcttta tctccacttc ctccacaacg ggcatcccgt
    56521 cccggtcaag cacaggctca ttcgtgaccg gatcaatctt ttcctgttcc tctttgattt
    56581 tataaggcga aggcgcaagg atacggatac ccctctcgcc cctgttcaca tggcgctcaa
    56641 aattcttctg ccatgcctta tacccggcaa cgtaggttgc gtcaggacat tgcatctcga
    56701 taagctggat attgtttgcg ctgtaattat ggaattttga catggtattc agatagcttt
    56761 tgtacttttc cccttcaaat aattccttca agccttcctc cagcctgtcc gttatctcct
    56821 tcactttctg tttttcagtt ctcgcatctg ccatacagct atttctcctt ttcctccata
    56881 aaaacaggaa gcagataggt ttccctctct gcccccgttc cggatatttt tatttgcagt
    56941 tatttttata aacattcctc tttgcttttt ggctttgcct tatcctgctc cggcgctttc
    57001 ttctgccctg ccttttcttt catctgcgac agtttatcct ttacggacac ccgccctcct
    57061 ttctccgctt ccttcccggc atccagactg gaagaaagcc gatccagctt ttcaaatgcc
    57121 ttatctatcc cgtcaatctt cttccgaagg ttctccaccg ccttttttac aggcttattg
    57181 attacccttg tcatgccgac acccggcttt tcatccgata cctctttcgt gcctttcccg
    57241 gctaacagcc tgcccacgtt ggaaacgctg ttcccgatct gcttcagttc gtccccgatg
    57301 ctgtcaatct ggttggctgt cttttcacag tccgtcatta catcaaccag acgctcccgg
    57361 taatcggaaa gcatggactt cacgccggaa attccggtct ggagaacctt gcacatctcc
    57421 gctttccctt tttccttaaa ggcgctgacc gcctgttgcg ctgtttccac caaattgttt
    57481 cttaccgatg acaggcattc cgaaaggctt gtgattttct cctgaaggtg cgccacttta
    57541 tccatgagct tctctgtcac agattttggc tggttttcct gcatctgcga aagctgctcc
    57601 cggacaccct gtaattcatc caccattgcg gtaagctgca tctgcatacc cgccacatac
    57661 cagaaaatcc ccatgaaatc ctgtgactgt ccgtccatat cctgctggtt aagcagttct
    57721 ataagctgtt ttaatgcctc attttcttcc atgacctgtt ttgtgttctg ttctgctgtt
    57781 tccatttttg caatcctcct ttaatttacg cataataaaa gacagtcttt tcctgactgc
    57841 cctctgcaca actgccattt caacttataa cttaataatc aatgacctct ttatccggaa
    57901 aaagctcaat gatttctttt attgctgcct gtacctgcgg attaccgcta aactccggca
    57961 taaagctgat aaatcctata tcaatctcac ttccggaaag tatgtcagcc tgtgaatctt
    58021 ccaacttgtt agtccccact acatggagat tgataccaat ggaagggata ccgttcatgc
    58081 gttccgacgg tatctgctga tataatctga ccgcttcctc taatgtcctg ataccctcat
    58141 gatattctcc aagattgtgg tattccccac actccgccac tgtaaatgtt acaatcgttt
    58201 cttctgtttt cttttttccc attgtcaaat tcctccgctt tcccattttt atgcaacaag
    58261 atacttgtct gtatcttccg tcatgtactg cccaagatat ttctcccggt gcggcatgat
    58321 aatatgcaga tttccatgca cattgatcca ttctataaca aaccagaacc caagccctct
    58381 gttatccggc ttccagatac cactttcgtc aaatgccccg ccacgcatca tataatctat
    58441 gatttcagga ttagacagtt tctccgcaag ttcccacctg ttcggtgact tttccctatg
    58501 acagccaaat ccacaataaa cgcaccctgt tctattgcat ccagtagttt caaatacagg
    58561 cttccccgta tcaaaaatcc ccaaatccat tgaattttcc tgtgcctgcc cttttccaca
    58621 atctgccact acttccccat atacatccgc aatgggtata tggttatggt agatatattc
    58681 cagcacatcc tgttctgtcc agaacgacat aggattgctg atagggcttt tcatgttaaa
    58741 accattacag ccacttttca gccagtttgt agtccttaac ctgctttcac tcgccatctg
    58801 cgctgtcatt ggcattttcc ctgtcttttt tgcataattg tgcataggcg cttttttcat
    58861 aatcgaacag cagtggtctg atatttcaaa aggagcttcc aaaaagaatt tatatctttc
    58921 tttattgtac atcttggaat attctgatgt ttccacccca ttttctttgt gcggatattt
    58981 cccctgcagg ataaggtagc ggacaggcat ttttatatcc gaacttggta tttcaccccg
    59041 gctcagactt ttgtacgctg tattttccct atcctcccgg cggtctatcc ctatcagatc
    59101 cgctatatag ctataattgg gaattattcc cccactgtct gcaccttttt cctgttctat
    59161 cagtttttcc acatatctcc ttgcgccata tacacagcct gccacttctt ttcctatcat
    59221 tggatagccg tattttataa taatctgccg gaaattcatt ttaggtctga tgatttcaac
    59281 attgtcatgc tgtttcacaa attccctcac ttccggatat tcaagtcctg tatccacata
    59341 tacagcccct attttcgggt acattttcct tgcaatatcc aataaaactg tactgtcctt
    59401 gcccccgctg aaactgatat aaacgccatc atccccataa tagtccaccc attcccggat
    59461 acggtattct gtcatccgta ttttagcgga aagcggaagt gactgcatct ggtataaatc
    59521 actgattgta tgcttgttca tgttgtcctc ctgtctgtaa aatgggaaca ggcagctttt
    59581 tatggctgcc tgttctaaat gttataaagt ttcttctttt cccttgcttt tctgaatctc
    59641 cggcttttcc ggcattttct gtccataagc cttctgccgc atctcggcaa gtttttcttt
    59701 tacggaaatg cgccctctcg gactgtctga taacatctgc cctttcccat gctccgctac
    59761 tttttccgat accgcccggt taatctgcgg cttaaaaggc gcatccgcca cagcttccgc
    59821 atcatgcccc atttcctctg tatccatttc ctcctgttcc ccgtcattcc ccggttcatc
    59881 gtccatatca atcccatcgc cgcccttttc atccatgttc aacagggcat ttaattccgt
    59941 caggcgttcc agtttctccg caagctccgc ttcctgcggg aatggctttg taacctccac
    60001 ttttgcggtt tcaagctgat gctccacgtt ttccagtttc tgcgccactt cttccattct
    60061 cttacccatg ccctctaagg cgttgcttaa cctctgcaaa ttccctaacg gatcagcgcc
    60121 gatttccacc tcatgactga tgctgccttt caaattgacc gtaaacttgg aaaagaacga
    60181 atcataggaa acactcattt tgaatccctg atattccccg attgtgaccg ccatattcgg
    60241 ctgttttgcg ctccggcaca tatcaatcag tgctgccccg gcttcttttt tgtccgtata
    60301 tacccggttc ccgattttta tagaaaaggt atctttatcc gggaacttat tctgtgtata
    60361 ggtctgaata tcggcacgat accccgcaag gcgttctttc atggaagcaa tctgtatcgg
    60421 gtaatgcttc acgatattgt cctccaaacg gtacttctgg ctggtatggt tcgcctttaa
    60481 cagttttagc ttcgatacct gaatatctaa atccatcttt tccttaatat agggattacc
    60541 ggttgcaaga gccttcacct ccgcataagt gagcgccgct tcgtctatgt cctcacagct
    60601 ccgcaccgga gatttgctcg tcataatctg cccgataaat ttctgcttat tttcaatgag
    60661 ctgccaactg tacgaatcga atgtgccttc cgtcacatac cggaaaatct ttaccttgtc
    60721 attcatgttg ccctgcctta aaatcctgcc ttcctgctgc tcaatgtcgg aaggacgcca
    60781 aggcacatca aggtggtgca aagcgataag ccgatcctgc acattggttc cggctcccat
    60841 ttttgcggtt gagcctaata aaaaacgaac ctgcccgctc cttacttttg cgaacagctc
    60901 cgctttcctt gtttccgtat tggcatcatg gataaaggcg atttcattct ccggcactcc
    60961 cttcgccatg agcttatccc tgatgtcctc atatacatta aatgtaccat ctcctttcgg
    61021 tatagataaa tcacagaaga taagctgcgc cgacttctgc tctttggtct gctcccatat
    61081 ttcaaacgcc ttctccacac aggttgtagc tttggaattt tcttcatccg ggagcatagc
    61141 atttataagc cgctggtcta acgccagctt tcttccatcg ttggttatct tgagcatatt
    61201 gtcgatgttc ggctgcactt tcctatccct gaccgcttcc gccctgtctg caagggaatg
    61261 taccatgtcc tgttggtatt cgctcggctt taacacaata ttttcataat ccgcttccgg
    61321 cacaggcagc tttaacatat ccggtgtctg aatgtcggcg ctctctttaa acagtgcaat
    61381 cagctccggc aagttgaaaa acttagcaaa ccttgttttc gcccggtagc ctgtaccttc
    61441 cggcgcaagc tctatggctg tctgcgtttc cccgaacgat gccgcccaac tgtcgaaatg
    61501 ccccaaacct aaacgctgca aggtattgta ctggagatag cgcatattcg tgtataactc
    61561 tgtcatgctg ttagaaattg gcgtacctgt tgcaaatgtg atgcccttcc ctccggtcag
    61621 ttcatccata tactggcatt ttgcgaacat atcagaagat ttctgtgctt ccgactgtgc
    61681 gatgcccgcc acattccgca tttttgtgta taaaaagaga ttcttatagt tatggctttc
    61741 atctacaaac agcttatcta cgcccaactg ttcaaaggtc actacattat ctttccggct
    61801 tgcatcattt aagcggctca acctcgtatt cagcgatttt tttgttttct ccatctgctt
    61861 aatggagtaa cgctccccat tctctgcttt caaggcttcg attgccattt caatctctgc
    61921 tatctgcctt tcaatcatcg ccatctgtct ttcagtggaa agcgggattt tctcaaattg
    61981 actgtgaccg ataatcacag catcataatc gcctgttgca atccttgaac aaaatttttt
    62041 ccggttcgcc ggttcaaagt ctttcttcgt ggcagctaaa atattagcac ccggatacag
    62101 gcgcaggaaa tcgcttgccc actgttctgt caaatggttc ggcacaacaa ataagctctt
    62161 ttggcacagt cctaaccgct tgctctccat tgctgcagca atcatttcaa aggtctttcc
    62221 tgcccctaca cagtgggcaa gcagcgtatt atccccgtat agctgatgcg ccacagcgtt
    62281 aagctggtgc ggtcttagta tgatgtccgg tgtcatgccg gggaatttta agtgtgaacc
    62341 gtcatattcc ctcggtctgg tggaattgaa aagctcgtta tactttgcac ataagtcctg
    62401 cctgcgctcc ggatcacgaa atacccaatc cttaaaggct tcccgtatcg cttcctgttt
    62461 ctggcttgca agcatggttt cctttttatt gagaactctc ttttctttcc cgtcctccgt
    62521 caccacatca aaaatacggg tgtcacgaag gttcagggaa tcttccaaaa tcctgtaagc
    62581 atttgcccgg cttgtgccat aggtcatgtt gacaagggca tttcccctgt ccgcattttt
    62641 ccccttcacg ttccactgcc cggtcacatt ggaatactgt acgcccattg ccttacggtc
    62701 aaacaggtat tccggcgttt caaaggtttc acgcatgaaa tcctcaatat attttgtgga
    62761 aatccatgtt gcgccgatcc gcacctcaat ctccgatgcg tcaagctcct tcggctgtac
    62821 gccctccaat gaagttacgt taatggcata ttccgggtgg ttctccgcaa aggttcttgc
    62881 cactgacagc ttctcccgca cattcccgct taaatactcg tctgcggttt cccattcctc
    62941 tgtcaccggg ttctggaaga ttacacccgc aagctccttt gtaatttctt ccccgctttt
    63001 acccgcaagc tgtgacatat acgctaagtc cacgcccgcc ttttcactga gcgataccgc
    63061 cagcgcttca ctggctgtgt ccacgcttgt cacaacctcc tgctttttaa tggttcgctt
    63121 cgtgaacata tccgccttgc cgatgaagtt cccctcatcg tccagccttt caagggaaca
    63181 taacaggcag taactggaat cctgattgaa cgccctttta ttggtctgtg agctgataag
    63241 accgaatttc ttggagaaat catcgtatag ctggtttaac tccgtctgct tgttttggat
    63301 catatcttcc gggtattctt ccaactggaa atttatcagc tcctgtgtgc agtcccggat
    63361 tgccaccatg cccttaatcc tctgctctgc cttttccgac acgtccacag gcttcataat
    63421 ggaattttcc cggtaatata cggtatcgtc caccaccgta tagctgtaat tcttcacatc
    63481 cggatcggcg ggtatgttct cctttgccag ttcatcgtca atctcgttaa aatccgcctg
    63541 ctcgatgctg ccctccacat gggaaagcgc atttttaagc tgtgctgaca agggaaggga
    63601 agtgtccggc aggcaggcgc tttccatgcc atgcgccccg gaaaccatct ccatttttcc
    63661 caataccatc tccgggtggt ctgcaaaata ctggttcatc acaataccgt ctttttccgt
    63721 cagatgtacc cagtccggct ctatatccat tacccggtca cgcttcttta aaaacagaat
    63781 atccgaagtg acctccgtac ccgcattttc cttaaacgct gtgttcggga gcctgaccgc
    63841 ccctaacagc tccgccctct gtgcaaggta tttccgcact tccgggtttt tcttatccat
    63901 tgtccccttt gaagtgacaa aagcgacaat gccgcccggt ctgaccttat ccagtgtctt
    63961 tgcaaaaaaa tagtcatgga taaggaaatt gtgcttgtca tactgcctgt cagacacttt
    64021 atactgtccg aaaggcacat ttcccaccgc cacatcaaaa aagtcattgg gataactggt
    64081 attctcaaat cctgttatct taatatccgc atgagggtaa agctgttttg caatccgccc
    64141 ggtcaacccg tcaagctccg ccccatacag cctgctttcc ttcattccct ccggcagaca
    64201 gccatagaaa ttccctatcc ctgcggcggg atctaacacg ttccctctgg taaatcccat
    64261 tttccccact gcgtcataga ttgtctgaat gatgaccggg cttgtataat gggcatttaa
    64321 cgtgctttcc cttgcggaag cgtattcttc cggggataac aggctcttta attcctgata
    64381 ttcattcgcc caattcgctt tggaagaatc aaaagcatcg gcaagaccgc cccaccctac
    64441 atattttgct aaaatctcct gttcttccgg tgtggcggtg cggtgttcgc cctcaatctt
    64501 ttcaagggtg cgtatggctt ctatattctg gcggaacttc tcttttggcg caaacccttt
    64561 cccggtgttt tcggcttcat taaaagaaat atgataattt actgctcccg acttatcaat
    64621 ctccggctct ttttctgatg ctttttccgg ttcttcctct gattcccctg tcagtgcttc
    64681 cacgtcaccc atgacctgcc tgataaacgg atcgttctct aaagcgtttt catctacgag
    64741 ctgctcatcc acaatgcctg ctttttccaa acgctcccgg actgcctgtg cgtcaatatc
    64801 ggggaaatca tcttccgtat cagaaatatc ttctttcgga atactccccg tttctggctg
    64861 tcctgccttt tctgtatcag tttctggtat tggctctata ttctccgttt cttcccgttc
    64921 cggttcttca gataaatctt ccggctctgc ctttgaaact tcctccgcag ctttttcttc
    64981 cctctgctgc tccggctcat tctcataacg tgccgcatat ttctgtgctt ccttcagcag
    65041 agcgtccatt tccaccgctt tttctgtatt gccacttaat gactgcatca ggacataatc
    65101 ggcggcttct aaaaacaaag cgtcataaac cgcttttccc tctaaccgcc tgtcagcgtc
    65161 ctcaatggca acctccccgg tatcctcatt ccagccgacc acatttttca tggacagcac
    65221 accgcagact tttaccacag cggacatctc cgcaagcctt tcaatcagcg ctttctcact
    65281 gtcactgatg ttattttccg gttcaggatt ttgtgctttc tgtccggaag attctgtttc
    65341 ctgctccggt acagccgctt tctccggctc cctgtcacgt tctatgtacc ttcttgcctg
    65401 attggtaaaa ccgtccagta cagccgggtg ggaagtgacg atataatccc ttgtctgcca
    65461 gtcagcggaa agcacaaggc tttttgccca ttccttattg ttcggggaaa accgcccgtc
    65521 atgggataaa tgtgtgattg tattggcaag gacaatctct acacgctcct tcctgtactg
    65581 cctgataacg ccctcggcgg tatccctcgg aagtgtataa ccgtcaaatt tttccgcaat
    65641 cgcctgttct atggcatttt tgcactctac ccggatacca tgctccagct tttcctgctc
    65701 ccggcgcata gcttcctctg cctgctcttt tttatactgt gcataggctt ccttgccctt
    65761 tggcgaaagg tatttatccg cttttacaag ctcgctgatg cgtttctcca ctacattcca
    65821 ttttaaaagg acttttgcgt atgggcttcc ataactgccc ttttccagac ggataccctt
    65881 tgcgtcatgt tcttcatgcc ctttatcact cccgattagt gcgtgggaac tgccgcctgt
    65941 tccatattca tttttaagga aagcaatatt atctttttta tcatgccctt ccataaaata
    66001 ctcataaatg cggaactgcc catgatgaaa gctactgccc cctgtcagcc gggtgtctat
    66061 ctcgtcctgt gtgataaaat cctcattccg cacctccaca ctgtcctgcg ccggatattc
    66121 tcttttttcc acacttaaat ctgctatctc tgaaagcaga tgctccggac ttttcacata
    66181 ccgccacttt atctgctttt ccccggcttc aagctgttct ttcgctttgg aaagctcccc
    66241 ggaaacaata tcccgccctt cctgcgtgga taaaagctca caaaggttcg tgatgctttc
    66301 cgggtggtta taattcttta tgggtatgtt ctccggcact tccccgatac cgtcccggaa
    66361 gaaattgaac aggtcatttg acaccctctg ccgctccact gcgtccacaa ggaacacttc
    66421 attagcgccc atataagtgc cattctccac catagaccgg acaatgccct ccacttcctg
    66481 ccagcccatc accgcaaccg ggttttcctt tgcagacatc ccgtagccga tgctcatgcc
    66541 ggattcactg aaccagacag aaataggatt gttcccaaag tcaaagcctt tcccggtagt
    66601 ccggtattcg tttttcaaaa actccgccat ttcctccggc gtcttgccct gctggtactt
    66661 tgcataaatg cggcttctgc tgttatcccg tccgccgcct gtacgcagaa tggcttcaag
    66721 ctgttctttt ggcaaagaaa aagcggcggg catgatgtat ttctctcctg cctgcgccgc
    66781 ttcaatcgtg ccgatctgtt cctctatcgt agggaataaa ctaagctgct gataaacctc
    66841 cgtttccttt ggctctggtt cttcccactg cggtatctgc ccctctttca gatattcgcc
    66901 tttctccata taaaaagcga tgctgtccct cacagtttcc catgacacag acgattccgc
    66961 tgtccggttc aggtagttcc ctctccagac ggtcagaccg ttctcatccg ccctgtaccc
    67021 ggctcttacc tccccaacat aaaactccgt atattcccca tgcctgtaac tgtttttgat
    67081 atattccgtc tgctttccct tatccggctc aaaaagcatt accccggcaa tatccgggca
    67141 tttatgctcc ataaactcgt caaactgcaa aatacccttt tcaatttcag acaaagaaaa
    67201 gccggataat gtgttttctt cattacccgg ctctggcagc tccttatttt cagttatttc
    67261 ttcctcattt acaggctgta tatcagctct ttcagcacga tttcctccgc tgagtgcctg
    67321 atgttgttca tcatccccac ccatttcatc tgatcggctg ctttcagttc ctccgtcacg
    67381 ccctctgctt tcgccatctg cgctgtcagc agttccatcc tctgctctgc ctgttcctga
    67441 atggtcagaa gatgctcttt cagcttccct ttcagcagaa gtccggtgta gattcccttc
    67501 ttgtgttcct gtaagtaatt cttcctcatc aacccgtact tcgtcagcat cccctccggc
    67561 tgctcgtcca tctgtaacat tggtatcaga taatccccgt ttttctcgta ggtcagattc
    67621 atcattattt cccctttccc cggcatttcc ggtctgtgtg gtaggttgta tgtcctgcgt
    67681 ttcactttcg cgctttaaag cattatagcg tgtgtcaaca gtatttgcaa gtcctttttc
    67741 aactaaattt ttcgatgctt catttctgtc atacgccccg attgccttcc caatttccat
    67801 aaggacaggc ttggataaat cggatatgct gtccccgata tgcgacaggg tttccaccgt
    67861 attaaattca tggatataag ggaactggat ttcctctgcc agttccgcat catccatgcc
    67921 gcaccgcttt aagaccatgt aagcgatact gtccgccagc gtttccctga cacgcacagc
    67981 aacattcaat tcgtccagtt cctccagaaa acttccctct ttcaggtatt ccatatccga
    68041 agcaagctcc ccataacaat cctgtgcaat ccgggcggca atctccctga tcctgtccgt
    68101 aaaaccagct tctttgttgg tatccccgta aatcccttcc agacggtcaa gcaccgcttc
    68161 ctgatgttcc tctttcattt cccatagctg cgggaaacgc ccgatacgcc ttgccttatg
    68221 cacgtccgat atgtcaaaga cataccgcag tccggtgtaa ggacttcctt cttcatcaat
    68281 cagggcaatc ccttttgccc ctttgtttac ccaacagtgc attttttcat tccatatctc
    68341 tatggaagcg caggctgtgg catccggtct ttgggcatag ataaggagct ggtctttgaa
    68401 cgggtatttg tagagccttg atgctgtgtt cagatatttc ttccagcttt cttcattcct
    68461 cgccacttcc tttgatgttt ctgcggaaag tgcggaaatt aaatcatatt ttctcatggt
    68521 aaacctccat taaaaaatgg ctgcaaaata caaaatgcgt atcttgcagc ctgttttttg
    68581 ttactttccg gcattactca tagaaaccat gttcctcaat gcctttttcc agaatggtat
    68641 gtatcagttc ctccagttcc acaccgttaa tctcgctgac tacaatcagc tttgcaaggg
    68701 tatctttctg tatggatatt gcatactgtt cctcatcggc acgaagctca tggacacaga
    68761 tgccaagtcc atccgcaatc ctgcatacca caccaagctc cggctctctg atgcccgcca
    68821 gaatatccat gattgtccgc tccggcactc ctgacattct ggaaagctcc ataatgctga
    68881 cttcttcctc tttcatcatg tttaataact tatctcctgt tgtaagcata tcttttcctc
    68941 cctctatttt ttcttcccgc cggaagattt cttttttgga aattccatga caaatttaaa
    69001 ctgtaccccg cttttttctt ccccgttttt ggtatagtga tattcctccg tcccactcgg
    69061 aatgatataa gcatcataag gcttgcccgc cttgctcttt aaccctttta acaggatttt
    69121 cttcccggca agcaaatcct ttacctgcgt atcagtaagg gcagctccca ttacccaact
    69181 cacgttcata ccgcatttct tcacgcagta cgcaccgaat ttacccttta ccacctgacc
    69241 gccgcagttc ggacacgtcc caagcaccgt ctgttcctgt gcgaacatct ttttctgttc
    69301 atcgctgacc tcatggtagg tgtgtatcag ctccgacacc atgttttcaa tatccgccat
    69361 gaagtcctcc attggaagct ccccttttgc taccagtgtc agggcatttt cccaatcggc
    69421 agtaagtttc ggggatttca caacgtctgg caggactgta atcagcttca atccgtcctc
    69481 ggtaggtatg atctgttttt tctcacgctt tacaaaaccg tcctttacca gcttttcaat
    69541 gatgtccgcc cttgtcgcag gcgtacccaa gcctttccgt tccacatcat cgcccatatc
    69601 ttccgccccg gcacgttcca ttgccgataa taacaaatct tctgtaaaat gcttcggcgg
    69661 ggaagtgaaa tgctcgctga ttttcgtctg cacaccgtca aatgcctgtc cttccgacag
    69721 ttccggcagc ttcttttcct ctttttcttc ctcctgattc ccggagattt taaaggaacg
    69781 cttaaaggca tcttcaaaag acttccaccc gttatgcgtg acagacctcc cggaaacagc
    69841 aaatatgtgc ccgttacagg aaaactctgc cttgactgtt tcatacagat gcttctcccc
    69901 ggtggcgcat aaaaggcggt tcgcaaccag agataagatt ttacgttccg tttctggcag
    69961 tgccgcaagg tcagctttcg caatctccat tgtggggata atggcgtggt ggtctgtcac
    70021 ctttttactg ttcagaatcc tctttatatc cggtctggga gccttatttt cctcaaacat
    70081 cagggaatgg aacaccgctt caatgacgct ttctgcggtc tgccccatgt catcagataa
    70141 aaactggctg tccgtcctcg gatatgtggc taactttttc tcataaaggc tctgtgtgta
    70201 ctctaaggtc tgctttgcgg taaacccaaa caggcggttc gcatccctct ggagcgtagt
    70261 aaggtcatag agcttcggcg gcatgactgt cttttcctct tttacaaccg atgtggtaag
    70321 agcctgccca ttctggcaag ctcccacaat ctcatctgct ttctttttat catcaatgcg
    70381 cccggtggcg gcatctatcc catccatcag gatatgtgcc atataatatt tttctttctg
    70441 gaaattcata atctttgctt ccctgtccac cagcattgca agtgtgggtg tctgtaccct
    70501 gcccaccttc aggactttcc cgccatacaa aacagtgaac agccttgtac cgttgatgcc
    70561 cacaagccag tccgcttcct gcctgcacag tgcggaatgg tataaattat cgtaatcact
    70621 ccccggctgt aaattctcaa acccttcccg gattgcgctt tcctccattg aggaaatcca
    70681 caggcgtttg atcggcttgt cacagcctgc catttcatac accagacgga agataagctc
    70741 gccctcccgc ccggcgtcag tggcacagat tgtagccgac acatcttccc tatgcatcaa
    70801 ctgaaaaagc acatcatact gcgctttcgt atccggcttg acctcatact gccatttttc
    70861 cggatttacc ggaaggctct catacgtcca tttcttccac tgttccccgt agctttccgg
    70921 ctgtgccagc tccaccagat gccccacgca ccagctcaca atatacccgt tcccttccat
    70981 atatccgtca ctgatttccg ttgcgccgat tacttctgaa atacttcttg caacacttgg
    71041 tttttccgtt atcactaact gcatttattc atcctctcct tctttatcct caaaaaaatc
    71101 gtcctcgctg tcctcgtttt cctcgtcatc ttcgtactct tcttcctcgt cctcctcatc
    71161 atcgtcctcg tcaagaaatt cctctttctt tttccggact accttgaaat aatagccgcc
    71221 gccgatagcg ataactgcca caactccaag aatgatatag gttgccatcg ggttttcttc
    71281 tgctttctcc ggctctggtt caggttcttc ggtattttct tccccgtccc cgtctggttc
    71341 ttccgtaagt tcttcttctg tttcctgttc cccgttgtta ttgggcagtg cgccctccga
    71401 cacagggatt gcagattcca gagcagcgga atttttcggt aaggtttcgc tgttgtccgc
    71461 tgtcacgttt aacagatcat tttccgtaac ttccgtcagg aagtacacca tttcttcctc
    71521 cccgtcccgg tcaatgataa ggtagaacac tttttccgat gcagtctgga ttgtataaaa
    71581 ttccttcccg gtttcgcttt tttccttctc cccggattct tccttttcct ccgatgcagc
    71641 cgcttccgcc attgcctgtt ttttctgttc agccgggctt aattctgata cggtattccc
    71701 gtcactgtcc gttttggtat gctccgttac ctgtgcggtg gcagaggaag gcttggttgc
    71761 ctgtgcatta accgggagct gctctgccgg gttcttctca ctgctgtcct ccttttccgg
    71821 atcggtgtaa tacgggttgg ctgttttata gatctctgac atatttccgg cattgtccat
    71881 agcggaaatg gtaaaatact gataacctgc gtcaaactgc tgcaggcgga tatttaagac
    71941 accgtttgta agctccgtaa attcgtaccc gttcacatac accgccttga tgccggaatc
    72001 cgtatcatgc gcctgtacgc ttaacagacc gtcactgacc gcagcgttta aggtaggctt
    72061 tgtgaaatca aaacatttaa tataacggtt tttctcatag gtcttgcccc tctggtctgt
    72121 cacaagcaca taaacggtgg tattttccga aatctccaca tacatatcct ctgtgatgtc
    72181 cgtccagctc ccgttctgtg cgacttttgc ctgtacggtc tttatggtga aattgccgga
    72241 atgtgccaca tcttctatgg agatatgtac ctttgtggtg tcattgtgcc acccggacgg
    72301 agtggagatt gtgattttaa cattcgggtt cacatattca cataagctgt aatcctcctt
    72361 gcaggcttca caatctttat caatggaata ctgcgtgcat ttttctgtac aagtacattc
    72421 cggctttgga atctcattcc ccgataccgt tccgccctct gtttcttctt ctgattcgcc
    72481 gccgctgtca ccgggttctg tttcagtgct ttcctctgct tctttgctgc cctctgttcc
    72541 ggtgccttcc tctgtttcct ctccggcact gctttcctcc gcataagcat ctaccgtatt
    72601 cccgctgttc gccataaccg cccctatggg catacagaac aataatgccg ataacagcag
    72661 cgacgccact gccctaactg ataacttttt cttcatttcc tgccatctcc tttgcgtttt
    72721 ctttttcttc caataacttc aaaatctcgt cctcgctgaa tttaatgagt aattgcagct
    72781 tctcggacga gattttatgc ttttcgataa tatccatttt ttcggctctt tccgccatgc
    72841 gcttctgttc ttccaaatcc ttctgcttcg cctgtaatgt ttcaagctgc gcccgcactt
    72901 tggtaagctc cttttcaatg cgttcctttg tcataaatgc ctcctaattt aacctgccga
    72961 aactgtaaaa atggctctgc cagtatgggg aattgatgct tgcgtaacta atcggatcgc
    73021 cgcagtgtat cattgtcccg ttgccgcagt aaatccccac atggctcacc gccccggctg
    73081 aattgtaagt cccggtaaag aatataatat cccctgcctt tgcgtccgat gcggaaactg
    73141 gcgtacactg gtcataaatc ccctgtgcgg tggttcgtgg aaggttatgt accccgctgt
    73201 tggtaaatac ccagcagaca aaaccggaac agtcaaaact tgtggaaggg cttgaaccgc
    73261 cccacacata cgggaatcct aaatattttg cggcttcctc cataagagcc tgcaccgatg
    73321 catcatcgta ggcatccggc ggtatggcgt tccccggcag tccgcccggt gtttccccgt
    73381 acagtgtgcc ttcgcctaca tcaaaataaa atagcgggtt gtaatactcc ccgttatata
    73441 aacattcgat atgcaaatgg cttcctgtgc tgctcccggt attgcccgtt gtcccgatga
    73501 ccaccccttt ttccactgtc tgccccgcac ttacgcttaa actgtccatg tgggcatact
    73561 tggttgtata accgtctatc tcaatcgcta cataattccc atagtggctg tcgtatgctg
    73621 ccgctgttac cgtaccgtca tgcgccgcat atacggttgt gcctgttggg actgctatat
    73681 ccacgccccg gtggaattcc tcattccctg tgacctcatt tttccggtat ccgtaatagc
    73741 ttgacacata ataataccag tagaggttaa gcggcgaagc aaactcttga agcagaccgt
    73801 tcgtttcccc atacatggaa aaaatctccg cctgttcggt atccattttc ccggaaacaa
    73861 ggctctctaa cggtatgacc gtaagtgtca ctctgaggat actgacctcg tattcttctt
    73921 cctcctcgta ctcatattct tcctcggttt cttccccggt aaccggatca gtgactgtcc
    73981 ttgtgccagt ctttgtgacc gtccttgtcc tcgtttccgt atccggcgtg agcgtcagcg
    74041 tatacatctc gtcaaaaaga gcctgtactt cactttccac cccgcttgcg gtaaactccg
    74101 tatggactgc ggataaatag ctgataaggg taaacgggtt atgcccgatt gcgccaagat
    74161 tataggaata ttcgtcatac cccggattgt ctgtttccac ccggtcaatc tctttctgca
    74221 ggtcaagctc cagacgggta aactgcaaat cagcggcgtc aatctccttc ggcttgctta
    74281 aatagctcgc cgctaaaatc gttgactgcg tatccgcaaa catcgccccg caggacgata
    74341 cggaaaccat aatcatcata aggagcagag ccatgatgcc caccgtcaca agcaagccgg
    74401 catttttcct tgcaaactcc tgtaacttcc tcgccacagt gaccgcaccg tttttcgtct
    74461 tttcaaacgc ctgctccgct gttttggcag atgccgcttt cttcctagcc ttgatgtatt
    74521 cccgcttgat acgctgtttc tgtaaccgct tctgcaacgc ttttttctgt atctgcgggt
    74581 tttcctccaa aaacttctgg tactggaaat tgacttcctt tttaaactgc tttttttcca
    74641 gctttgccac cttcgcccgc tgtttctgct cttttccctt tatctgcctt ttgacgaaag
    74701 aaaacagttc ttcccctttc tgttctgatt tgtgtgcgcc ctccactgct gaattttctt
    74761 tctccgtttc agcaatcttc ccatgcacaa aattccggct ctcattctgc atccggcgca
    74821 tggtggtttt cggtatgccc tcctgcttga agggtttctc cttatccaga gggacaacca
    74881 catattttcc cttcccggtt ttctcgtcaa atactctctg caaggtgtat tcccttgtct
    74941 ttggcagctt tgcccttgcc ttctgtacct tcttcccggc tttccctgcc tgccgctgtt
    75001 tcttttgcag ctttttactg cctgtaaatt cagagcctcc ttccccctga aacagatttc
    75061 cggtattctc cgcaaaagat tcttcggtaa aggttttatt ttccgttttt tcctttgtgc
    75121 cgccttttac ccggtgttcc ttttctaccc gctttttatg gtatttccct tttttctgcg
    75181 actgcctgta agtatccctc cggtggtaat cttccgtatc cggctgtttt ttctccattt
    75241 cctccggctg gctgaaattg tcctgcccgg taaatccact gctttccctg acaaaatcag
    75301 gcttttcttc ctgccccggc ttcgcatcgg acttttggac tttttgtcca gaagtggtct
    75361 ggtacatctg ctttttcgct ttggcttttg aagcatggtt cgattcccgc tgtctggtat
    75421 ctcccttttg ggaatccaca cccttatgtt ccgaaaaagt ttgattttcc tgtaactgcc
    75481 catttccgga cttctggact ttttgtccaa aagtttcctg atgcgcctgc gtaacttttt
    75541 ccgcctgcct tttcccggct gaaccatgcc ccggcttctt ggtatcggca tccctcggct
    75601 gataggcagc actgccgcca cctgtaaagg cattatcggc tcccttacgg aactccgcat
    75661 ttacttcttt acggtaggcg gtatcctgtt ttttcttccc tttcttttct gccattaacc
    75721 ttcctcatct tccttcgtta cggattcctc cggttttgtg ttcataatcg caaaagtttt
    75781 tgtattagcc gggtatttat ccacgaatgg gataaccaca ttgtcaaaca gtatcagacc
    75841 gcttcccggt tcggaattag tgacgtgcat gagctgtttc tccgacaatc ccaacttatc
    75901 cgccaagata tgctggtctt tggcgttctg gttcagcaga tatacaaaat cgctgttccc
    75961 caagatgccc tcgatttcct ccgatttcag aaaatcgccc acgttctgcg tcaagcctgt
    76021 cgggattccg ccccatttcc tgaaacgctt ccaaatctcc accgaataga tagctgtctg
    76081 cttttccttt aaaagcaaat ggaactcatc acagtagtat cttgtggcaa ctttgcgctc
    76141 ccggttctgc gacaccctgt tccagaccgc atcctgcaca atcagcatcc caatctcttt
    76201 taactggttt cccaagtcac gaatgtcaaa acacatgatc cggttgtttg cgtccacgtt
    76261 cgtcctgtgg ttaaaataat tctgtgagcc atgcacatac agtacaaggc tgttggcaat
    76321 ccgaaccgcc ttctgcttcg cttccctctg catctctggc gcaacgtccc tcggctcata
    76381 ctttaacagc gcattataca aatcttccag tatgggcata ttctccggct tcgggtgctt
    76441 gaaatacccg tcataaatgt gtttgatgca ggtgtcaata atgcccttct cgtcattttc
    76501 cagaccgtcc ttccctccgg caatcaaatc acacagcgta atcaggaagt cactctttag
    76561 cttcaacgct tccttatccc ctttatggga aagctgaatg tccatcggat ttaagaagtc
    76621 ttttgaattg gtagcaagcc ttaccacctg cccatgaagc gcctgcacca gagggaaata
    76681 ctctccttcc ggatcgcaga caataatatc gtccttcgtg ataaggaaac aggacaatat
    76741 ctctctcttt gcggaaaaag acttgccgct tcccggtgtc cccaaaataa ctccgttcgg
    76801 tgtacgaagc cttttccggt ctgccataat catgttgttg gaaagtgcgt tcagaccgta
    76861 ataaatagcc ggtgcgggca tgaaaagctc ctgtgtgcag aacggtacaa ggacagcggt
    76921 gcttttggtg gtaaggtttc tctcaatccc cacgtcattg cacccaatcg gcgcacttgc
    76981 catcagcccc tgctcctgta aatactgcaa acaccgtaaa ttacagtttg cctgctggat
    77041 aatgccggac accctctgcg tcaggttttc aagctccctc tttgtcctcc cgtaacaggt
    77101 aatcaggaat gtcattttga taagtttctg gttgcttgtg ttcagatcgt caagcagctc
    77161 caatgtgtcc ttctcatacg tcacgatgtc agtcggcaga atatccatat cgtaaccgct
    77221 ccggactgcc ttcttctgtt cctcaatctt cattttctga atgtcggtaa gcgcacgttt
    77281 tatcatcttg attgcttcca ccggatcaat ggtctgcatg tgcatggtaa gggtaaggtt
    77341 atcatcaata tccagcagct tcttaatcat ctcgtccgta aacttcggcg caatcatgtc
    77401 aaggtaagac acgctcccgt aaatgctgcc agacttgaaa cggctcggat aacggaaatc
    77461 aaaccccggc ggcgcaatat agtccttgac cgacttcccg gactctgaca gttccttaaa
    77521 ggaaaaacgg aaaggctcca tcgtaccctg attgaaatac tcatgtaaga tacggagcct
    77581 ttccttcccg tcaagacctc tggcgtttgt gccgatattg tttaaattat gtaccacatc
    77641 tttctcaatg ttgcttaact tgctccttgc ttctttgatg cctgtgcttt ccacgccgaa
    77701 aataatgtac tttgatttga tgatgccatt gttacccttt gccgactggt gctttaacat
    77761 ctgtgtatat tcctcacgaa tatcattaaa atcatcgtcc tgcaggggag tgtcgaactg
    77821 ctccgcaagc gcctgctcgc tgacctgcct gttgaataag aacaactgga atcttatgga
    77881 cggatcgaaa tagttaatca gcttgctgta ttcctccaga atatcagcct gatcctccac
    77941 ctccagcaag tcatagttaa tatcaaaaaa ttccaccatt tttgtataat aagtgtccgc
    78001 cacctgacag atgccgtccc ggtacatttt tttaaatgta atggttttct gtgcggtgtc
    78061 cggcttcgcc tgttctttgc tattcccggc aaggacacgc ctaagctctg acagacgttt
    78121 cttttccgaa aaagtcagcc ctgccttttc cggtgtctgc ctatttttct gcggctttgg
    78181 ctttcccact gccgcctttt gctttttctt caaggaaaca tacctccttc ctgatttttt
    78241 cccgttcctc caactgctcg tagaggtttt ccgatttata cggtctgatt cccggcgtga
    78301 gtaccttctg ccggagcatg aagtataaaa tcttctctgc cgggaaaccg tctttttcat
    78361 acatagccaa aaagaagaat ggcagcattg cacccaccat gataatcgcc gccccctgtg
    78421 tgcctaatac cccttttgtg aggaaataca agggaacacc cacaagggca gctcccgaaa
    78481 aacagataat ctgccttttg gtaaggttca atgctacttt tgtcttgatt ccactcaggt
    78541 cttttggcac tggtactgaa attgccataa attttgctcc tttcgtgggc aatgcccgcc
    78601 aagcacagcc ttctgtgctt agtgggcatt gaaaattgat ttgcttaaag agcctgtctt
    78661 gaataagctg aaacagagga ttacggtata tgccgctacc gaccataatg cgctgtgcag
    78721 gttgcccgcc actgcgacgc ttgccaccag cacagcataa atcgccacgc ataccatgat
    78781 aaagaaaccc tgaaacgcca gtgcgacaag cccctttaaa tagttcgttc caattgtacc
    78841 ccattcccgg ttggtaactg tcgctgccgg gattggcgct accgatacat aaagtaaggt
    78901 aagaacccgg cgccttgcca tatcactatg gcaggtttcc gaaaactccc ctccgaaccg
    78961 gacttacacc tctcaatgta tccggctctc cagatgtcag tctaatttcc ctgcgtgtaa
    79021 cttatcgtga cagtcaatac agagtgccat tgtcttgcgc ctgcgcccaa tcatggcgat
    79081 ttcccattgt ttcctgccac ttaaatcttt gagttttcgt acatggtgta cttcaagcgg
    79141 cacattctct gcgccgcacc actcgcattt attcgcttga agtcttttta tcaagctgtt
    79201 gcgcccgtag ttctcaacca ctcttgccac tatgtcgggg ttgccgcttt cgactttggt
    79261 attccggcgg aacccattgt tgtagaacag cactttaccc actttgccgt ttttcttcgg
    79321 atattccact gcaaaatctt tcccttggcg gtacttgcgt ataattctgc tgattcttgt
    79381 tcggtatttt ccagcaaaag ttttgagcat actgtatctc attacatagt agaagttatt
    79441 gagtacggac acgttgtttg cgagccggta gtagttatac aatccacgga tttctgcatt
    79501 gtactggttt aggatttcca agtcgtccag gtgcaacagg cggatgcgcc ggactggttc
    79561 ccagacctct ttgtttccat tctgtttgtc gtatttaatc ttgagggcat tgtaggagag
    79621 caggcgtttt aaccatttat catggggaac atagagcagg acttttccgt tgttcactcg
    79681 tctggtagcc ccggttttgg tctttttgct gtactcgcct ttggtgattg tgacctcgta
    79741 ccccagaaac tttgcaaagt catgtccgtg ggtaatcagt gtcttttccc cggacatttc
    79801 cagatgaagt ttttcccgga taaaacagcc cacttcttgt tttacctgtt ctgcgtcctc
    79861 tttactgccg ataaccccta tcagaaaatc atccgcatac cggacatagc aaatcctctt
    79921 atagctgtcg tccatctggt cactgtacgg catggatttc aaacttcgcc gcagttcccg
    79981 gatttccgca attaagtcct ctttttcttc ctcgctcatt ttagaaagat ttcttttaag
    80041 ccgctgttct tttccccggc aaacgtccag cttcttcttg aacgcaggat tgattttacg
    80101 gcggtttccg cagttgaatt tctctgcata ttctgccata tagctgtcca gttcgttcat
    80161 atagatgttt gcaaggattg gactgatgat agagccttgg ggagtgccgg agtaagtatt
    80221 gtgataattc cagtcctcca tatatccggc tttcaaaaac ttccatagca gaccaatgaa
    80281 atgttcgtct gcaatccgct tccgcagaat gtcaatcagc acatgatggt ctacattgtc
    80341 aaaacagccc tttatatccc cctcaacgaa ccactttgtt cccgtaaaat atttctgcac
    80401 atatttgagt gccgtatggc agcttttgtt tatgcggaaa ccgtgggagt agtcgctgaa
    80461 agttggctca tagatgctct ctaagatgag ccgcaccacc tcctgtatca gtttgtcgtc
    80521 aaatgacggt attcccagag ggcgcatttt cccattggat ttcgggatat acgttctcct
    80581 cgccgggttg ggttggtagc tgaaatcacg cattttttca atgagggcgt ttatccttgc
    80641 cattcccata ccgtcaatgg ttttgccgtc tgttccggct gtcatgttgc ctggtttcgc
    80701 ctgtatccgc tggtatgtca gcagatagaa ttgtggattg tacagattgc ggtataaccg
    80761 cccatacttg taactcttgt tacacgcctt ggatttcagg ctttccaaca cattttcagg
    80821 acttctcata atgcctcacg cacctttcct ttttatgaat tggttgacat cctgcctccc
    80881 ttcgccatgt agacggcttt cccgccctcg gactactacg gaggctccgt tgccatgccg
    80941 gatattcagc gtcatctttc ttgggttttt accccttgaa atttatcgcc ttgcggcatt
    81001 acgcatagcc ggataatccc ggcgttccgg tttaggcaat ctccagttag acactttggg
    81061 aaaagcgtat tgtgatgtcg gtaatgggtt ttcgtccttt tccgcttatt gcggctggct
    81121 gtcataagta tcgtgcggtc tgtgtttacc tgtcacattc cgctatgaca tacggcgaat
    81181 acaaccatcc tgcgccgccg ggtcgagtat cccgcctcgg actgccctta aagcagttta
    81241 gccttgttcc tcattcacaa tgttgcgtct tgccgctcag tcgtgggtag atggtttccc
    81301 caacttgcga tttttccggt acgctattgt cccccttatg gtttccctcc ggagtaaacc
    81361 gaatgacgct aaagtgacgt ttttcacatc tttgatactt ttctttaccg gcttgccaaa
    81421 gccggattcc caaaatgccc gcgtaccgcc tttggatgaa aagcggcact tctggacgcg
    81481 cggtatattt caatcatgcg cccgtataaa atgacggtga tgaggacgga catgattttc
    81541 atacacaggc tgattaccat agtttccaga cctaaaccga tcagctcccc gatgcccatt
    81601 gtgtcaatct ggctgttgaa catggaagta agcgttgctt ccacatcaag gcttgttgag
    81661 cctgatatgg aagatgccgc ctgcgtcact acatggcttc caacgtcaaa taccgccatg
    81721 acaatatcaa aagtcttgga aagcagcatg acagcgatgc aagccttaaa taaaaaacgg
    81781 aagaacaggc ttgtatcgaa gtcatgcata ttgtttttgt ctattaccat tgtgataagc
    81841 tcataaatca gcacgaaact gataatcagc cctgctatgg ggattaccac attctccgac
    81901 agcgtcctta ccatgctgaa tatgccggag ttccatgtac ttggtgtctt gctgacttcc
    81961 ccggcaatcg tgcctacctt gtcattgacg tcggtaaaca tcgtgccgag gttgtcaagc
    82021 acccacccct gaagcatttc ctttatgaaa tcagtgattt tgtcaatgat tccgcccatg
    82081 aagggttatc tcttatgaga acagtgtgga aagctgtgga atcaccgtct gcgccacaat
    82141 gataatgccc ccgccactca taagctgttt aatgccctg
//
LOCUS       DAMJXI010000009        81178 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.009, whole genome shotgun sequence.
ACCESSION   DAMJXI010000009 DAMJXI010000000
VERSION     DAMJXI010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 81178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 81178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..81178
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.009"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            32..1144
                     /locus_tag="PC465_000899"
     CDS             32..1144
                     /locus_tag="PC465_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5009 domain-containing protein"
                     /protein_id="HDF2648224.1"
                     /translation="MNSRIKSIDIIRGLSIALMIVCNNPGTWMRMYPQLRHAVWHGVT
                     LADFAFPFFVISLGVTIPISINSKIKNNKSTLSIILSIFKRSILLILFGFFLNYLGNP
                     DLDTVRILGVLQRMGLVYFVTSLVYLLLKKLNVGSTATIITFLCISTFIIVGYYILAK
                     PYGFELEGSLAQLVDLHFFKGHLYKPEFEPDGFLTSIVAISSGMLGCTMGCVLLKENL
                     GEYKKFFKILVMSIILLIGAFIFNQYFPFNKRLWSSSFVLLMAGSYGILLSIFYFICD
                     IKNKSKIFTPIIALGSSPIFTYMCLEILSHVFWNVPKLTNKVDYPTTLVEWTTYELIT
                     PWAGTTWDSLIFSLLYVLFWVIVMSIMYKKKIFIKI"
     gene            1398..3422
                     /locus_tag="PC465_000900"
     CDS             1398..3422
                     /locus_tag="PC465_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2648225.1"
                     /translation="MKKTTKLLATGMLSVAMVAPNVALAAENTTANTESNSDININLQ
                     RKSVVLGSKSNASVKFKEKLNADSITLNFMCYDMPLEATLNYNEKTDSYEGVINYNKD
                     PEYLNVWELQSIKINGKDEQKVLNKEDLESMGLNLKDYDVTQEFIISDANSTKAVNEY
                     MRKTSAPVKKLAGATRFETAVEISKQGWKDGSSKVVIVNGELAADGITATPLASTYDA
                     PILLANKDDIPESTKAELKRLNPSDVIIIGDDGSVSQKAVSQIKSAVNVNVTRIGGVD
                     RHETSLLIAKEIDKYHDVNKIYIANGYAGEYDALNISSKAGEDQQPIILANKDSVPQG
                     TYNWLSSQGLEEAYYIGGSQSLSSKIIDQISKIAKNGTSKNRVSGADRHETNANVIKT
                     FYPDKELSAMLVAKSDIIVDSITAGPLAAKLKAPILITPKTYVSAYHSTNLSEKTAET
                     VYQIGDGMKDSVINSIASSLSKHNAPTEPDNSGSAAGKTVVIDPGHGGSDSGATSGLN
                     GGAQEKKYTLNTALATTEYLRSKGINVVMTRDTDKTMALGERTALSNTIKPDLFTSIH
                     YNASNGAGNGVEIYYKVKDKNGGTTKTAASNILKRILEKFNMKNRGIKTRTLDNGKDY
                     LYVLRNNNYPAILVECAFIDNKSDMDKLNTAEKVKTMGTQIGIGIEDTVK"
     gene            3642..4328
                     /locus_tag="PC465_000901"
     CDS             3642..4328
                     /locus_tag="PC465_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HDF2648226.1"
                     /translation="MSGYTNDECEIPKIKSYPGADKEIASEIDYSIVKGTVLFDLYQR
                     IMDLVLSIIGLVIGLPLIAIFGILIKIEDKGPITYKQERLGKCGRRFYIYKLRSMRTD
                     AEKFGAQWAEKDDPRITKVGKFIRKTRIDEIPQLFNILKGDMGLIGPRPERPNFTVQF
                     NEEIPGFINRLAIKPGLTGWAQVNGGYEITPEEKLKEDIYYIKNRSILLDFKILFKTV
                     KVVLTGDGAR"
     gene            4423..5478
                     /locus_tag="PC465_000902"
     CDS             4423..5478
                     /locus_tag="PC465_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp7"
                     /protein_id="HDF2648227.1"
                     /translation="MIKKISTILSLVLLISISSTIGVFADANPKRELIEGSIPEISTE
                     LNKRAFKDSKEVILVNEESIVDSISATPLAYAKNAPIVVTKSKNLGRVTRNYLKELGP
                     EKVTIVGGLKAVSKDAERNIEKMGMKVERIRGKDRYDTSLKIAREMYRTVGFDEAFLL
                     SSTTGLENAISVYSYAAKSGMPIIWAKDEGFEEQIDFLKGKNLKKIYALGDSKEFIAE
                     IDSNLKNIEGIKQINKSSTNVDLIKKFYDEKDIKKIYTARLDFGSRSDVNEYISLGVV
                     SAKENMPILICSDNLSRAQDKFLKDSNINDVVEVGYTVGDYSLFKSIFNLTFLSCIVL
                     ILLLLLITFRALRYESK"
     gene            5593..7149
                     /gene="murJ"
                     /locus_tag="PC465_000903"
     CDS             5593..7149
                     /gene="murJ"
                     /locus_tag="PC465_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HDF2648228.1"
                     /translation="MSKTAKAALWIMAATMFSKVLGFLRELVLANFYGTGMYADVFVL
                     TLNIPGLIIAVIGSAVATTYIPMYFETKKRLGDEGALKFTNNVLNICYIMAIVIAIIG
                     LLFTEQFVTVFAAGFRNDPAKFQAAILFTKIMISGVLFLSGSKIFSSFLQVNDSFVIP
                     GLIGIPYNIIIIAAIALSAGKNVWILPAGALLAMASQLLFQLPFAFKKSYKYKPYINL
                     KDESIKELVNLVLPMLVGVAVGQLNIFVDRLLATTLGDGKLSALNYANRLNEFVMALF
                     VTSIITVIYPKLAKMSGKDNKEGFISTIVKSSNCIILVVLPISIGAIILAEPLVRILF
                     QRGKFDALSTDLTSIALRLYSLGLLACGVRDVLYRAFYSLSDTKTPMINGSIALIINI
                     VLNLILIRPLGHAGIAISTSTSNIITVILLFISLKKKNGYFGGDKIIKTGLKSLVASG
                     VMAVATLLIYNNLYAFMGSGTIKEIISVGAGVLGGASVYTVLIVLFKVEEMDLAFEFL
                     RKGKQKLLRR"
     gene            7195..8901
                     /locus_tag="PC465_000904"
     CDS             7195..8901
                     /locus_tag="PC465_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HDF2648229.1"
                     /translation="MDYKNNYEMWLNSPYFDEQTKNELLSIKDDEKEIQDRFYKNLEF
                     GTGGLRGIIGAGTNRINIYTVRRATLGVLNYIMKTQGEEGKQKGIVIAHDSRYMSREF
                     CIEVAKTLSAYGVKAYIFEELKPTPELSFAVRYLKCAMGIVITASHNPKEYNGYKVYD
                     SDGGQICIDMANDIIAEVNKIDDYSTIKSIDFKEALSKNLITILDNEVDDEFIKAVKK
                     QVLRQNIIDEYGKKLKIIYTPIHGTGNKPVRKVLNECGFENVMVVKEQELPDSNFSTV
                     KYPNPEEKSVFNIAIEMAKNNGTDLIIGTDPDCDRVGIVVKDSSGEYVVLNGNQVGSL
                     LVRYILESLVEENKLPKNNPTIIKTIVTSELGAKIAKAYNVDCLNTLTGFKFIGEKIK
                     AFEESNDRSFIMGYEESYGYLIGTHARDKDGVVSSLMICEMAAYYSSKGMNLYEALID
                     TYNKFGYYKEDLKSVTLKGIDGIKKIKEMMLYFRSVKIDNVADVKVDKILDYKDSVDD
                     LPKSDVLKFLLEDGSWIAIRPSGTEPKIKFYFGANSDNQEDVEFKLNNLISYILNVVD
                     SI"
     gene            8923..9996
                     /locus_tag="PC465_000905"
     CDS             8923..9996
                     /locus_tag="PC465_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="HDF2648230.1"
                     /translation="MKVYNVIMAGGGGTRFWPLSRQEVPKQLINLSGEDALINETINR
                     IDSLAKKDDLFIVTNEKQLEALKDIVKDKCLDSNILPEPCARNTAAAIGFAAFNIMKK
                     YGDGVMCVYPADHYIKDEKEFKSILEKAIYIAENNDKLVTIGITPTFPSTGYGYINFN
                     RENTIEDVAYEVVEFVEKPNYEIAKEYVNSKKYVWNSGMFVWKVSKILEDFKRYLPKV
                     YEKLEDISKYLGTKEEMEKIKEIYPTIQSISIDYGIMERSNDVIVVPGDFGWNDVGSW
                     DSLGAIYPTDDEGNIKRGENITIDTKNSIIYSDDKLISTIGISDLIVVSTNDAVMVCR
                     KDKAQDVKKIVEQLKEEDRQEYM"
     gene            10008..10730
                     /locus_tag="PC465_000906"
     CDS             10008..10730
                     /locus_tag="PC465_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2648231.1"
                     /translation="MIPKKIHYVWFGGPKGNIENICINSWKEKLPEYEIVEWNEKNFD
                     IEKEIKGNKFLEECYKRKLWAFISDYTRIKVLYEQGGVYMDTDMQILKDITPLLENNR
                     LICGYEDDREYINGAIIGVEKGHPFLKDLLEYYEKEVLTSSLFTIPKIMTHLMEKNYK
                     KIDLNNYEEGIRVYDKEYFYPFGFKEDFTPECITENTFGIHWWGKSWAKKRNYFLESK
                     HLTGVNKIWKCCKIFASNTLRS"
     gene            10746..11903
                     /locus_tag="PC465_000907"
     CDS             10746..11903
                     /locus_tag="PC465_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HDF2648232.1"
                     /translation="MKTLNDDRNIMIRKYLYIFVLFIILLRKYMISFIDPNMDIGMIK
                     SALFYSSIGILMLLFLFDKRKSITEMVLVGVCVLLYLLNREGAILLIVLLAVSAKQID
                     DKFIVKNYLIISACFLMVAILLFNLFPSLIFNQEVHYRYIEKIDMLVTRMDFGLGNPN
                     SVFYHMVTIYAAYIFLRYKDYNKWDRIILFGSAFFVYQTTYSRTGFFTILAGLIFVEI
                     IRWIDIKKIKGLPMLLKTLPIILTLFSVIIGKVFDKSTLLNRLLASRPKFWHVYLAEK
                     GNFLKPFGNSYSPAIKATNPLDSSYVYIISVLGVVACILFMYLMYKGIESFIEKDKKA
                     YLVALFIFLLYSFAENLLLEASFSFAVVLLIKEVILNDKREIDLWKMKSRR"
     gene            11906..12745
                     /locus_tag="PC465_000908"
     CDS             11906..12745
                     /locus_tag="PC465_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2648233.1"
                     /translation="MLISLIMPTLNRYDDIYLLMDSLENQTYKNFELIVVDQNDNSKV
                     KEIVDKYIDKLDIKYIKSSKKGLSYNRNVGIDNAVGQIIGFPDDDCVYENDTLEKVIN
                     FFNKNKDYKIYSCKTMDSNKVDAFKKMYDGTCDITSSNVLDTITSITFFIDFEGKDYT
                     RFDEKLGVGGEFGAGEEIDYVLNLLSLGFKGKYFGNDIIYHPAKKHSKSKEKYQKDYN
                     YGRGFGALCKKEIVYRKNYKFAKVMVSKLVRNIGGLILSSNRDYHSATIKGRINGFRQ
                     YKL"
     gene            12760..13935
                     /locus_tag="PC465_000909"
     CDS             12760..13935
                     /locus_tag="PC465_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HDF2648234.1"
                     /translation="MDKVKFLINMLLAFFIYPFNKHKFNGRDIWLIGGHSGDIYNDNS
                     KFFYEYMLKEHNDVETYWVVNKDSKVFDKIPGKKLIRGSVENYLYYYNSKAIVFSHAP
                     SADIAPYNFAVPVLNYFHKKTIKVFLNHGTISFKKRKPMNKKFKNIIDNLYKSYNIVT
                     ASSEFERNVMVNDWGMLDDSVYIIGNARYDNLPTNEVAQTRDILYTPTWRDWIKFSSG
                     KFTDTDYFKNIMNFLNDDKLNKILDEKDINVKIYMHHLMHEFIDDIKENITGKRIVFL
                     DKGVTLANEIRKSAANITDYSSVAIDFLYMNRPILFYQFDLDEYMEKVDSYIDLKSEM
                     FGSLAYNNDEAVNKLIDIIENNFEVMDNQKNERNKFFRYNDNKNCKRIYDCVLSKIK"
     gene            13964..14713
                     /locus_tag="PC465_000910"
     CDS             13964..14713
                     /locus_tag="PC465_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2648235.1"
                     /translation="MKKNLVSIITPMYNSEKFIEATIKSVLNQTYQEWEMLIIDDCST
                     DNSPNIVKSYMQQDSRIKCIKTETNKGVSNARNLALSKATGQFIAFLDSDDQWNSSKL
                     EKQVNFMLENDYVISFTSYELMDENDKKLNKVIKVPPNVDYRRLLKGNILGCLTVVID
                     KSKLDFEIRMSGVRHEDYVLWLSILKKGHIAHGINEVLALYRKSSNSLSGNKIKAAMW
                     TWNIYRNIEKIPLYKAIYYFINYGINGIKKS"
     gene            14735..15643
                     /locus_tag="PC465_000911"
     CDS             14735..15643
                     /locus_tag="PC465_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2648236.1"
                     /translation="MYKYKFTVFTPTYNRAHLLENLYNDLKAQTYDFNDFEWLIVDDG
                     SSDSTKELVEKFISENKLNIRYIYKENGGKHTAINLGVKNADGELFFIVDSDDGLIKD
                     SLEIANDEWDSLENKEGFSGVVGLCVYPSGDLIGTEMPEDKKICHFADLYFKYGVKGD
                     KSIVFVTDELIKFPFPERKEVRFLPESAVWNEMSKYYKVICVNKPMIIRDYLDDGLTK
                     NILSKNALRGRALEFLYLINQNTYPLSRYPYMWIKNYINLARYSLLSDSHYFGELRKV
                     SDKLLYLALFPLGYYKYIGQRKLVSK"
     gene            15691..16443
                     /locus_tag="PC465_000912"
     CDS             15691..16443
                     /locus_tag="PC465_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2648237.1"
                     /translation="MNEPLVSIITPVYNSEEFLSETIKSIQNQTYKNWQLLLVDDCSK
                     DNSSEIIKSFRKEDARIKYIKLEKNSGAAVSRNVGIKNAEGRFIAFVDSDDLWDSRKL
                     EIQIEYMLKENVGFSFTSYRYMRQDGSKTNKVARAPKKIDYEGLLRNTIIGCSTVVID
                     KEIVGEFSMPLVRRGQDTATWLQLLKKEKYAYGIQEDLVNYRLVGNSISSNKIKALKR
                     TWNTYRNVENLSLPKSLYVFCFYVFNAIKKRV"
     gene            16397..17764
                     /locus_tag="PC465_000913"
     CDS             16397..17764
                     /locus_tag="PC465_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HDF2648238.1"
                     /translation="MYFVSMFLMPLKKEYKFYILGGKKMKIAIAGTGYVGLVTGVCLA
                     EVGNENVVCVDVDEQKVKSMKLGIAPIYEEGLEELMVKNYNRGRIDYTTDYKKAYEDV
                     DVILIAVGTPERSDGSANLDYIKAVAKQIAETVTKDTLVVIKSTVPIGTNEEIEDYIN
                     RNLKNDVKVELASNPEFLSQGTAVKDTLHASRIVIGVESEWAREILEEIYKPFNQPII
                     VTNRNSAEMIKYASNNFLALKISFMNDIANLCEIAGANIEDVALGMSYDDRIGSKFLK
                     AGIGYGGSCFPKDTKALHWLSEHNGYELKTVKAAIEVNESQKLKLVRKASKLVESFQD
                     MKVAVLGLTFKPDTDDIREAPSIPNIKYLLERGARVTVYDPIGVNNTKKIFGDSILYA
                     DSVDDAIEDAEICFIMTEWKDVLNYDIHKYKEKMKNPLVLDGRNCYKIKDMEELGIEY
                     YSIGR"
     gene            17770..18861
                     /locus_tag="PC465_000914"
     CDS             17770..18861
                     /locus_tag="PC465_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2648239.1"
                     /translation="MKTVCYLADGSNPHTLKWCSFFKNKGYDIHVISLNGGHMEGIKI
                     YNFGSNVEELKNENISKKTGYLGSIKQIKKLVNEIKPDILHAQYASSYGFIGSLLGYH
                     PYIISVWGTDIYDFPNNGFIQKQIIKHNFRKADYIFSNSRDMAKEANKYTAKHVDVTF
                     FGVDMDRFKPMEVEKEDAFVIGIIKSLEKKYGIEYLIQAFKMLKDEYKDKKIILKIGG
                     SGSQMDNLINLAKELGIENDVQFLGRISPENVSKTFNSFDVTVFPSLREGFGVAAIES
                     EACEVPVIVTNVGGHPESVWENETGLIVEPKQPEEIKNAIIKLMENDELRLNMGKKGR
                     QFVRENYEVNLNFNDIEKIYDSIFDKYKK"
     gene            18945..20858
                     /locus_tag="PC465_000915"
     CDS             18945..20858
                     /locus_tag="PC465_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDF2648240.1"
                     /translation="MRESIDLEKESFFNRLFKKYKFRHLTLLILDICSVLVAFRMSLS
                     LTGNLNAFTTNDIIISVCIYIVLHIVSFRLFKCYNTLWRYAGEEEIISIFVATLAYLI
                     PIYIINKLLGFDYPIMFYVLNTIFIIMFTSGARIAYRAIRIVMNKTYSRGKVSNILII
                     GAGDAGEMVIQELKRNPELKKVAVAIIDDDKNKIGRIIHNVKIVGTTSDIKDVVEKYN
                     VDEIIFSIANIEKRRKKDIIDICKNTNCKIKTIPGIYEIIDGKVDIKQIREVEIEDLL
                     GREPIKTNLREISNYIEGKVILITGGGGSIGSELCRQIAGFNPKELIIVDNYENNAYS
                     IQQELLRKYKNKLDLKTVIASIREEKRMDEIFNKYKPEVVFHAAAHKHVPLMESSPGE
                     AIKNNIFGTLNIAGLSSKYRAKKFVLISTDKAVNPTNIMGATKRAAEMIIQTMNAESQ
                     TEFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTHPDIIRYFMTIPEAVGLVIQAGA
                     MAKGGEIFVLDMGEPVRILDLAKNLIKFSGFEPDVDIKIEFSGLRPGEKLYEELLMSE
                     EGLLDTEHKKIFIGRPIDVDREKITKYLKLLREITNNEEVEKIDGIMRELVPTYIKPE
                     DANIKEIATTREK"
     gene            21057..21764
                     /locus_tag="PC465_000916"
     CDS             21057..21764
                     /locus_tag="PC465_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2648241.1"
                     /translation="MMNIKNKKHILKKFIAMVLIAGVVTVEAGAITASAAEPTNSPMS
                     ATVDQCDFLNVRSGASANDAVVGKINTGDKVEVLELHSNGWIKIKSVDNVTGWVNGDY
                     LTIQGGNVDAKVQNVLNLAFKQQGKPYKWGATGPNSFDCSGFTSYVYKNGAGVNLPRV
                     SRSQATVGKKVSRAELKPGDLVFFGSGGSINHVGLYVGDSKFIHSPQTGDVVKVTSMA
                     PGTNYAKRLITATRVLQ"
     gene            22066..24177
                     /locus_tag="PC465_000917"
     CDS             22066..24177
                     /locus_tag="PC465_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding glycosyl-hydrolase Cwp19"
                     /protein_id="HDF2648242.1"
                     /translation="MKKISILVLSLIMTLTMCSVSSFADSSNDKEMRAAWISTVYNLD
                     WPKTKNNEAKQKKEYTDLLDKLKSVGINTAVVQVRPKSDALYKSNINPWSEYLTGTQG
                     KDPGYDPLPFLIEEAHKRGMEFHAWFNPYRITMADESIDKLPANHPAKKNPSWVVKHG
                     NKYYYDPGLPEVRKYIVDSIAEVVQNYDIDGVHFDDYFYPGVSFNDTATYQKYGKGQN
                     KDNWRRENVNTLLRDVKASIKSIKPNVVFGVSPAGIWRNKSSDPTGSDTSGNESYVGT
                     YADTRAWIKQGLIDYVVPQLYWPIGLKAADYSKLVAWWANEVKGTNVDLYIGQGIYKQ
                     GQSSYGGQNIAKEIVQQVTLNRKYSEIKGSMYFSAKDIANSTSIQKDLKSLYSSSEEP
                     VTPPSNVKVEKLRGDERYDTAVAISKKGWATNSDTVVLVNGYSIVDGITSTPLATSND
                     APILLVNKDNIPTSTKNELKRLNPSKVILIGGNNSIGDKVESEIKDTLSNVSINRVGG
                     SDRYSTSLMIAKELVKTNPVEKLYITSGTGEADSLSIASKAGEEKQPIVLVSKDNVSD
                     EVYNWISDLKVKDAYFIGGNLSISDSVINKLDKVITNDVSKNRIAGENREETNGKVIQ
                     KFYPNAEYSSMFVSKSNQLVDALTSGPLAAKLKSPVVMLGNSVTSAQKTALEPKKTTL
                     VYEAGDGINQNTLNTFLNLVK"
     gene            complement(24375..25340)
                     /locus_tag="PC465_000918"
     CDS             complement(24375..25340)
                     /locus_tag="PC465_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDF2648243.1"
                     /translation="MSKLKKFVILLAFLVVIFPISVYGYFYYKLSAIHDSSISSDLLD
                     NNDHKNEDGIINILLMGTDARPNEDSSRSDAMMILTIDNKHNDIKLTSLARDSYVDIP
                     GHGKQKLTHAYAYGQADLLIQTIEENFNIDIQNYACVNFESFMYIIDAIGGVEVTVEK
                     GEIRELNKFIPETYKWNKSDDKGSIQYIRNSGKQTLNGYQALSFARIRHNDTAFARDG
                     RQRQIIQAIIKKTETLPVTKYPGLLDAVLPYVKTNMKPNAILSLGAQVLKMGDLNIKQ
                     FEFPIDDEIHSTGGIYGKAGWVLRFDPDTLDILHDFIFNDIEFKQ"
     gene            complement(25625..26581)
                     /locus_tag="PC465_000919"
     CDS             complement(25625..26581)
                     /locus_tag="PC465_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDF2648244.1"
                     /translation="MSGLKKFVIFLALLVIAFPVSIYGYVFTKLKTIQDDSINTEALS
                     SNDYKNEENITNILLLGTDARPGEEVSRSDAMMILTIDNKNKSLKLTSLNRDTYVNIP
                     GRGEQKLTHAYVYGQANLLIETIEENFQLDIQNYAVVDFFSFMDIVDALGGVTVTVDK
                     SEIRELNKFIPETYKWNKNDNKGSLKYIRNSGEQKLNGYQTLAFSRIRKNDSTDERDR
                     RQRSVIQSLINGVKDLPVTKYPNLVNTILPYVKTNMNPNEIISLGKELLSIGNLNLKS
                     MEFPLSTENGRKIGNAGYVIPFEEYELDAMHDFIFKDIMVED"
     gene            26949..27737
                     /locus_tag="PC465_000920"
     CDS             26949..27737
                     /locus_tag="PC465_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2648245.1"
                     /translation="MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGR
                     QYQNLIKKFEDIKDDMMFISENGTLVVYKGKEILSNPLNKELVNEIIETTRSIKGKKI
                     VMSGKKYAYIESKDEAFIQEVSTYYAKFKIVEDLTKVEGDILKIAVFDFKGAEHNNNI
                     YFEKFSDRAQVCISGVEWLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEM
                     MKSAYHSYAMENANEHLKQIARFRAKRNTENGVVDKIKEVIKIG"
     gene            complement(27860..28330)
                     /locus_tag="PC465_000921"
     CDS             complement(27860..28330)
                     /locus_tag="PC465_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HDF2648246.1"
                     /translation="MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLL
                     IKESKIFDAKDFNYFNDVEEDIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYK
                     KDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENATQIENKILNIIKK"
     gene            28469..29113
                     /gene="uppS"
                     /locus_tag="PC465_000922"
     CDS             28469..29113
                     /gene="uppS"
                     /locus_tag="PC465_000922"
                     /EC_number="2.5.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="di-trans,poly-cis-decaprenylcistransferase"
                     /protein_id="HDF2648247.1"
                     /translation="MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCR
                     DLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPE
                     ELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDL
                     IIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG"
     gene            29156..30061
                     /locus_tag="PC465_000923"
     CDS             29156..30061
                     /locus_tag="PC465_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2648248.1"
                     /translation="MKKKLLDGKITLIICKSVKIYTKKGEEMSKGNNNNNSRNKSKKT
                     SHLNRKKRKLNKKKLAVLICFTVLFLFIAFKATQGVVALVKSMDKSNKTNQQQNVNSE
                     QFDLGNEEENKKKKYTVFIDPGHGGNDKGTESKTSNRYEKDLNLQIAKKLANKLSKQK
                     DIQVVVSRTDDTYISLKDRAILANNSSADVLVSIHLNAEKNGNTATGIETWYRNKATD
                     GSKELAQTVQSTIVSYVKVRDRGIVENNFEVLRESNMPAILIECGFLTTPSEEQKIIN
                     EKYQDQLAEGIVQGVLSYLDSKGNK"
     gene            30376..31923
                     /locus_tag="PC465_000924"
     CDS             30376..31923
                     /locus_tag="PC465_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2648249.1"
                     /translation="MNKNSMTRIYSLNKIIFIIIGILGIVLLTRHIEVDIKVLILILL
                     TLFSINVFISYLKIKLYEDKINLGLINNSDKFINITKDENFLKHVQNYIISNEKENCV
                     MACFDLCRLKLINDIYGYELGDEVLNNILSNLKNYFGKEAIYGKLKSDVFVLIIKLEN
                     REQKIPYLVNLIKNKIVILSQIDSFKMDINIEASIGIYKFNNNEIDIKKAIDNADMAR
                     LKSKGLKHIEYVEFDNAMEEEIQSIMKIERDLFLAIKNKEFVIHYQPKVDSSTGNIIG
                     SEALIRWLHPSLGMVGPNKFIPIAEKNGLINNIGRWLIQEVFITINKWISEGINVLPV
                     SINLSRVELYKNDLVDFFKLMFNTYNIPKELIELEITETTALRDVKFISERLYEIKSL
                     GMNISLDDFGVGNSNFINLKGIPLDIIKIDRSLILDIVTNTKTKFMVKAIVNLSHDLN
                     VTVICEGVEDMHQVKVLSELGCNFIQGYVFFKPLDEMNYKKLLTDGSYINLKDTLLDK
                     CMTVEEE"
     gene            31926..32324
                     /locus_tag="PC465_000925"
     CDS             31926..32324
                     /locus_tag="PC465_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDF2648250.1"
                     /translation="MISEDVDYSIRIIRAIFNNGEDKPIDAKMILKSEDIPILTLYRL
                     LRKLCANNILTFNKEDGKTYMLNVSLDTISLRTIVEVIDGKIYINKCTRYVSNCSNCL
                     KGCKVNRELLEIEKEIYKLLSRKSIRQILE"
     gene            32364..34097
                     /locus_tag="PC465_000926"
     CDS             32364..34097
                     /locus_tag="PC465_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HDF2648251.1"
                     /translation="MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKT
                     LKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIH
                     RHILNYCIYGADIDEKAISILKDSLTNKKVVNDLDESDIKINLFCCDSLKKKWRYKFD
                     YIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGIGSVIT
                     PRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYID
                     VFKIKNEDICINKFETLEELLKSSKFEHFNITQRLLSDEWILVNKDDETFYNKIQEKC
                     KYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYIVDKSEY
                     RLIYSNDIDNENTNKRILDEIIGLYKTKLENRRECKSGIRKWYELQWGREKLFFERKK
                     IMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLDKFSYEYLVGILNSSVYDKYFKI
                     TAKKMSKNIYDYYPNKVMKIRIFRDNNYEEIENLSKQIISILLNKSIDKGKVEKLQIK
                     MDNLIMDSLGI"
     gene            34329..35540
                     /locus_tag="PC465_000927"
     CDS             34329..35540
                     /locus_tag="PC465_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF2648252.1"
                     /translation="MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGA
                     YIIQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEG
                     IDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIA
                     SSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQ
                     NINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEE
                     YCFDKFRSMSNETIQYICNLLNIKRDASLRTVMESVIPKLGEVLGLPKDFSYKDLFYC
                     IYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRNLASNFEVRPKISIKKNKNTKLLT
                     NCIIKDIKNQS"
     gene            35733..35993
                     /locus_tag="PC465_000928"
     CDS             35733..35993
                     /locus_tag="PC465_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HDF2648253.1"
                     /translation="MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAK
                     SIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE"
     gene            36347..38059
                     /gene="ptsP"
                     /locus_tag="PC465_000929"
     CDS             36347..38059
                     /gene="ptsP"
                     /locus_tag="PC465_000929"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDF2648254.1"
                     /translation="MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLEN
                     AVAVSKEELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTESVNAEYA
                     LNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAH
                     DLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVV
                     FNGDTGEVIVNPDEETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGT
                     PNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEIQYEAYKAVLEGMDGKPIVIRTLD
                     IGGDKELSYLSMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASVHGRLRIMFPMI
                     SSLEELLQAKEVVKEVLAELDSEGVAYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSI
                     GTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQ
                     KMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADDVLNMGTAEEIKSYIEK
                     TFNI"
     gene            complement(38851..39516)
                     /locus_tag="PC465_000930"
     CDS             complement(38851..39516)
                     /locus_tag="PC465_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648255.1"
                     /translation="MKGNIVQYNFADIEEEVYSLDYAIAWNTDEENVNIIPFTNKFCK
                     ESIESFCLGKINNFVEILNEGFVENHHYVHLDKMISVPKKKVNLVYQQDTHGYLLRDD
                     NDNLIPAKITSEQSKSISSKMELFCAGEEKCLINILLKADPSYILDVDSIKDKNILNL
                     GYESIDRYKEYNFDDDKILIFFINKKRYSVIMKKTNNSDNDLVSRNNAIKELFTNKAG
                     NLN"
     gene            39860..41290
                     /locus_tag="PC465_000931"
     CDS             39860..41290
                     /locus_tag="PC465_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HDF2648256.1"
                     /translation="MDIKNKIKSIFLPEKNDYLDDEEFEYDIENNEEDLKEDNKVHLN
                     DLSRVKYDYRELKDIENQTEEMCLLAVKQDGTIIEFVKDKTYKVCMEAVKQTYKSLKY
                     ITNQNEDICIEAVKQNYRALYYINNKTENVLIEAIKNASTYDVMEVFKFVEEQTEDVC
                     LAFIERASKNDVAEILKGIKEQTPAICLEAVKKDGKSLAYVKEQSNSICLEAVKENYS
                     ALSCVKEQTEEICIEAVKQNDFALYYVNEQTEKICMEAVKRSYMALQYVNKQTEEICL
                     EAVRIDGRALQYVKEQTEEICLESVRQNGKVLQYVKKQTENICIEAVRGSFEELEIKE
                     ILSYVKIPTERIFVEAVKQNGKILKYVENQTELICLEAVRENYNALAYVKEQTEKICL
                     EAVNQSYEALKYVKEQTEEVCLKAVKQDYRMLKYVNNQTEKICLEAVKQNYRALEFVD
                     NQTEKVCLEAVKQNRKALQYVKQKQS"
     gene            41658..42236
                     /locus_tag="PC465_000932"
     CDS             41658..42236
                     /locus_tag="PC465_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HDF2648257.1"
                     /translation="MFKRYAEKMTSVLICNNMIDNNESKVYSYGFEILIAFIVNITTM
                     LFIGFLFGKFTYVLFFLMCYCPIRQFSGGYHADNYFRCLLTFIFIILSTILIIENINI
                     DLFKNIIMIIASVSWVGICVLCPIEHRSNPISDREKLVYKKTAIFISTVVLLITILSL
                     SLSIFVDYFTYSAFAMFWIFVMLVLGKLKAKV"
     gene            42266..42412
                     /locus_tag="PC465_000933"
     CDS             42266..42412
                     /locus_tag="PC465_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HDF2648258.1"
                     /translation="MKKFIVRFMKFASSLALSTAILSANSTCPWIIHQPKVPKEISNL
                     KKTN"
     gene            42717..44096
                     /gene="scfB"
                     /locus_tag="PC465_000934"
     CDS             42717..44096
                     /gene="scfB"
                     /locus_tag="PC465_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="HDF2648259.1"
                     /translation="MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEE
                     ILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAH
                     DCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNF
                     EVVKQLVDYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVN
                     DNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGF
                     KLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYADRQLQGDGFKFFHFMIDLNQ
                     GPCVIKRITGCGAGNEYLSVTPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMF
                     REAHVYTKEECKQCWNKFYCSGGCHANAINFNNDISKPYELGCEMQRKRTECSIMIQA
                     KLMLEGATN"
     gene            44125..44622
                     /locus_tag="PC465_000935"
     CDS             44125..44622
                     /locus_tag="PC465_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HDF2648260.1"
                     /translation="MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRG
                     DEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILD
                     NAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKKYIDESYEWYLEAA
                     QNQKY"
     gene            44920..46584
                     /locus_tag="PC465_000936"
     CDS             44920..46584
                     /locus_tag="PC465_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HDF2648261.1"
                     /translation="MRISYRNLKRYREIGYVLIKYGFSFIVERLNIEGIAYKIPLFDP
                     PEEIKNMTTGERMKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDS
                     NIAIDIFKEEVGLSIEEIFLEFKEEPIAAASIGQVYEGVLKTGEEVIVKIQRPNIEKI
                     IKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFK
                     NSDEVYIPKVYSEYNTKKILVMEKVNGTKLSDVEKIRRLGYNTKTIVEIGVRSFFTQV
                     LSHGFFHADPHPGNIFVVAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKII
                     YLLIEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMP
                     AQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNVEEI
                     LLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVG
                     SSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD"
     gene            46597..49047
                     /gene="recJ"
                     /locus_tag="PC465_000937"
     CDS             46597..49047
                     /gene="recJ"
                     /locus_tag="PC465_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HDF2648262.1"
                     /translation="MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEI
                     FMNPSLDYLRDPFLMKDMQKAVDRIKLAVEKNEKIWIYGDYDVDGVSSTSILCLYFKS
                     IGYNVDYYIPNRLEEGYGINEDAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDV
                     IITDHHECQSEIPSAFAVINPKQEDCNYPFDSLCGCGVAFKMIQALTPKEEFKTSMYN
                     YLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHI
                     GFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILEEKNNERQMIEAKMYHEAE
                     EMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLGIENGEATGSARS
                     IKGFNIFEALIKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIE
                     NVNVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKL
                     SIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPK
                     SASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSIN
                     GFYRAMSDISLIDLDFNINYNIIEDVSKNTDKLELIFSPNIDKIDLKRYNNIILYDYL
                     YNKGEYSYIYENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALIKKEI
                     DLDMVNIRETFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKLDLNE
                     SLILNNLKNLEKQYNSSY"
     gene            49060..49572
                     /locus_tag="PC465_000938"
     CDS             49060..49572
                     /locus_tag="PC465_000938"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HDF2648263.1"
                     /translation="MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEEL
                     KDKDVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLE
                     IHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLS
                     NYDVNSLIKY"
     gene            49646..51853
                     /locus_tag="PC465_000939"
     CDS             49646..51853
                     /locus_tag="PC465_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003229747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HDF2648264.1"
                     /translation="MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSG
                     EPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGV
                     TKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYK
                     AKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGI
                     VELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCY
                     AVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAE
                     NGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYV
                     FTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTS
                     SNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPL
                     VEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEE
                     DLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGV
                     AIHRADCPNANNNGDFFQNRLVEVSWSSAGKGKFEAEIQIKAIDRRGIVNEITHIVAM
                     DKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN"
     gene            51878..52327
                     /locus_tag="PC465_000940"
     CDS             51878..52327
                     /locus_tag="PC465_000940"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HDF2648265.1"
                     /translation="MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDY
                     MIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNAARPELA
                     NNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF"
     gene            52342..52956
                     /locus_tag="PC465_000941"
     CDS             52342..52956
                     /locus_tag="PC465_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2648266.1"
                     /translation="MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKE
                     NELNIEYIILTHGHGDHIGYVKDIKEKTGAKVVAHVDEKELLNDKNKNLSYTMRCGAQ
                     EFDADIYVNDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDL
                     YSGDFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM"
     gene            53047..54603
                     /locus_tag="PC465_000942"
     CDS             53047..54603
                     /locus_tag="PC465_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="HDF2648267.1"
                     /translation="MLYVFLKGHDYKYEVAELIKLFTSEFKFKDSNANNNIESKHLIN
                     RLIYENGVLFSSTEYYENGNLKYESIQNIKNMNLEFLDGFDSSKTIEEFLNSLDSESK
                     RNFKKLCKENIKKSMFLVLKQVFNSYVPWGILTGIRPVKIVHNLMDKKLDDNSIRTIL
                     KDNYFIIDEKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQ
                     FGHLKREYVYKLIEEIKGFAKVIKETKKEVETLYIGGGTPTTLDEEELDLLINSLFNE
                     LDLSKIKEFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSD
                     LVDCFNMARRMGFDNINMDIILGLIDEDLNMVKNTLEEIKKLSPESLTVHTLAIKRAS
                     NLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKE
                     GYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKR
                     KKEEVYKNVD"
     gene            54593..55855
                     /locus_tag="PC465_000943"
     CDS             54593..55855
                     /locus_tag="PC465_000943"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HDF2648268.1"
                     /translation="MLTKAPRGTKDITPKEAYKWRYVENKFREICALYGYEEMVTPIF
                     EHTELFKRSVGDTTDIVQKEMYSFKDKGDREITLKPEGTAGVVRAFIENKLYADTQPT
                     KLFYVTPCFRYERPQAGRQRQFHQFGIEALGSDTPSMDAEIIALAVQFFNEVGLNDLV
                     VSINSVGCPVCRKEYNALLKEYLDSKADILCDTCNERREKNPMRVIDCKNPTCKENIK
                     DIPFIADHLCDDCKSHFDKLQEYLKEMNINFVIDKTIVRGLDYYRKTAFEIISNDIGA
                     QSTVCGGGRYDGLVEQLGGPKGISGIGFGLGIERLLLTLEGNGIEIENPQSTDIFIVT
                     IGEEANTRSFKLLKDLRQNHISADKDHIERSVKAQFKYSDKINSKFTIVIGDDELKND
                     TATLKNMKTSEQTTVKLSTLVEELKQKL"
     gene            55929..57716
                     /gene="aspS"
                     /locus_tag="PC465_000944"
     CDS             55929..57716
                     /gene="aspS"
                     /locus_tag="PC465_000944"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HDF2648269.1"
                     /translation="METLKGLKRTHYCGELREKNINEEVVLMGWVQKKRNLGGLVFVD
                     LRDTSGLCQIVFDTDVDKEAFEKAEKLGAEFVIAVKGKVCERQSKNPNMPTGDIEIFA
                     TELRLLNKSETPPIYIKDDDDVSEALRLKYRYLDLRKPSMQRNLKLRHKVMNITRNYL
                     SNNRFCEIETPFLIAPTPEGARDYLVPSRVNPGKFYALPQSPQLYKQLLMVSGMDRYF
                     QIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDVMSMIEGLLEAIFKEVLDVELALPL
                     PKMTYAEAMSKYGSDKPDTRFGYELTDISDVVCNCGFKVFADATQPGKSVRGINVKGK
                     ADDFTRKQISSLEEHAKTYRAKGLAWMKVGQEGVTSPIAKFFNEEEMNAILTRMNAEV
                     GDLLLFVADKNSIVFDALGQVRLEVANRLNLLDKNVYNLLWVTEFPVFEEDEETGTFS
                     AMHHPFTSPMDEDLDKLEEGDKSSLRAKAYDIVLNGYEIGGGSVRISNSDVQSRMFKA
                     LGFTEERANEKFGYLLEAFKYGTPPHAGLAFGLDRLVMLLAGTDNIREVIAFPKNQNA
                     VCPMTNAPTLAEDEQLEELSIKVDIKDNE"
     gene            58175..59407
                     /locus_tag="PC465_000945"
     CDS             58175..59407
                     /locus_tag="PC465_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HDF2648270.1"
                     /translation="MQEREELVLNPVPKEERVGWLAPLFNMLGSNIAISELMVGGTLI
                     LGMTLSNMIITSIIGNLILVAIIMIQGYIGYKEGLNTYVLAKGAFGEIGGKYLISLLL
                     GITSFGWFGVQAGVAGLSVQKIFPSVNLTLVTVILGLFMVVFALYGFKAMAKFNYLVI
                     PPLMILMVWGVFKAFSTYGVEAIYNYTPQTTMSMVEGLNIVVGLVIVGAIISPDQLRY
                     TRRVKDIWIISFLGLGIISLFQQVAAGVMSMGAPTWDITEVLANLGFGWVAFVILILA
                     SWSTNVSNAYSGGLALKTIFPNVKRNVLTLVAGLIGTIIAATGIIFKFQSFLSFLGIA
                     VPAIAGIMWCEYYFIQGRTYKHREGINWIAVISWLIGFAASYYSSKINFLIPPINGIV
                     VSMVIYYILMKCFGIKDK"
     gene            59421..60227
                     /locus_tag="PC465_000946"
     CDS             59421..60227
                     /locus_tag="PC465_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase"
                     /protein_id="HDF2648271.1"
                     /translation="MGRKVKIGIIQQHSVLGDVKKNIEKAVEMIDDLGKQGADIICLP
                     ELFATGYNLESLGGVKTLELIREHNKYIEESMSEAAKRNNVYLISPYGTLEKGSTHVY
                     NSAVIFDRKGKIMGEYCKNHLWSLEAVYFKGGEKVEVYDADFGRFGVMICYDAGFPEV
                     SRELTLKGSEIIFIPSAWRIQDEDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGK
                     SKICNPRGTVITQLDTYREKYVLSEIDLDEIKKYREDIPYLKDRKSSYNI"
     gene            complement(60339..61208)
                     /locus_tag="PC465_000947"
     CDS             complement(60339..61208)
                     /locus_tag="PC465_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2648272.1"
                     /translation="MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELG
                     VQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKKELQDTSLENSGEVKILSPAAAN
                     VLPSLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
                     LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSP
                     YTIYALIKSLQGVGFICGKSWGLSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVL
                     LFKNFLINYFKNI"
     gene            61580..63007
                     /locus_tag="PC465_000948"
     CDS             61580..63007
                     /locus_tag="PC465_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp14"
                     /protein_id="HDF2648273.1"
                     /translation="MKLTKSISSMLCLSLVLSLSPVAYANEISRTTVENTLVGQDRYQ
                     TAVEVSKKGWSSANEAVVVNSESIVDALAVTPFAKLKNAPILLTEKNDLNSQTEKELK
                     RLGVKKVYIIGLSSSISNDVQKQLESNNLTTDRVGGSDRYQTALSIAKKIEGLKDISE
                     IAVVNGYTGLADAVSIASVAATNGMVILPVSDASGISSFKDFIESKNINKSYIIGSTN
                     AVSDKIKQSLPNSERIGGADRNETNGKVIEKFYTSNKLNNVFVAKDGMKNQNQLIDAL
                     AVGVLASKENSPVLIVGEQLSATQKSVFSNKNATSITQVGSGGNENAFKELKDLQANS
                     NNKRVMYVTNTDKVNIRNDATIEASVIGYLNNGDEVEVLDVLKTGWVKIKYNEGIGYV
                     SGSYLTNNKPDNSNENIKIKYVKEKDGLNVRKGPSTEDEKIGHLSYGSKVETIEMFAT
                     GWVKIKYNGGYGYVSNDYLSDTPVI"
     gene            complement(63083..63352)
                     /locus_tag="PC465_000949"
     CDS             complement(63083..63352)
                     /locus_tag="PC465_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648274.1"
                     /translation="MKFEYYYLIQDIAGILLAFIGLRMSIIGFRILSMKGLSINTLLI
                     VIKYCLFTIAGLNLLISKFGIRHWIWSVCMLIISIIINPRIKVSK"
     gene            complement(63355..64797)
                     /gene="nhaC"
                     /locus_tag="PC465_000950"
     CDS             complement(63355..64797)
                     /gene="nhaC"
                     /locus_tag="PC465_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDF2648275.1"
                     /translation="MKMNTERKIPSFRYSLLVMLAIIALTSVGIVVFNASITTMFLLS
                     WLIVVPAAMKLGYTNDEIEAFGFEVGKDAFQSNLIILSVGVLIAAWIAAGTIPTVVYS
                     GLTIITPKYFLLTTLIVCSLTSVATGTSWGTLGTSGIAMMSIGTSMGIPLGLTAGAVI
                     SGAFFGDKMSPLSDSTNLAAAVCKTDVITHMKHMFYTTGPAYVICIVLYTVIGFKYSN
                     NTIDYVQINQIKDVLNSNFHIGLVAMIPIIFLLLLLLLQKPPIISILSSAIMGLIIAV
                     FQEGEKIGDVLNYMLSGFTIDTGFVYANKLLNRGGIMSMAETVLLVFVVFVIAGILQK
                     TGFLEVLLQPLITKIGKSRTKLVGSTFVVSYFANAFSSSMMFTSVFVGTLMSPIYKEF
                     KLKPQNLSRIIEDTATLGGPLIPWNSNAVFCAQTLGVSPLEFIPYCFLSWITPIISFI
                     YGVTGFTMLTYTDDEIEELEIFDTAQRRVD"
     gene            complement(64822..65988)
                     /locus_tag="PC465_000951"
     CDS             complement(64822..65988)
                     /locus_tag="PC465_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2648276.1"
                     /translation="MNYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAA
                     PCIIDSLKNRLEQEIYGYTTRPDSYNESIVNWLDRRHNWKIKSEWLIYSPGVIPAISL
                     LINELTKANDKIMIQEPVYSPFNSVVKNNNRELIISPLQKLENGNYIMDYEDIENKIK
                     DVKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPMAS
                     ISKEFEKNTITCMAPTKTFNIAGLQSSYVILPDEKDYKLLDDAFTRIDIKRNNCFSLV
                     ATEASYNNGESWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGL
                     SDEELESILVQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKNAIN"
     gene            complement(66213..68333)
                     /locus_tag="PC465_000952"
     CDS             complement(66213..68333)
                     /locus_tag="PC465_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2648277.1"
                     /translation="MKQMELAIVSLKKDAGEIYENQIRQFLGDNLKINLYSFEEGNLK
                     FFKEKLILLSAYLKYDEIVKLSHYDAQIIVPKLTFEKNSIDMISKLEKDKIIYVYNLS
                     KDMAIETISLIHRLGIDNINILPCYPEIEFTPTDAVILTPGEKILPKFKNCEVIDLKY
                     RIIDLSCIVEIATKTKLKHLIKDDLIKKYVEKIIPTSYSTGELLLDANKFERQFDLLL
                     SIIDDGIICTNNDGIIQFYNHMARKILSINANEMIDSFVGDCIKDINFQSILTNKTPF
                     FEKLIKINHIDINLEIKHIQLNVFDGFILKMTKFSQLEKKQAKLRAQLVNSGNISKYT
                     FDDILGSSIQTINTKKIANKMAQSNSSILIIGESGTGKELFAQSIHSASRRKDGPFVA
                     VNCSTFQENLLQSELFGYDEGAFTGAKKGGKIGLFELANNGTIFLDEIGEMDLNSQSK
                     LLRVIQEKQVRRIGSNNVIDIDVRIIAATNRNLKELVSKNMFRRDLYFRLNVLPLKIH
                     PLRERPADIFEIFGSLKYDIPCNFILSEEVKEIFKMYRWEGNVRELRNLGEYFCYLEK
                     DIIEICDLPEYILDTIDSNYSRTVCNKVSDNIKKYQFNIGKDKNIMEYDYNFKKSLDE
                     YIFILDNLKKAYDLKERIGRKSLCKIALEENRFLTEQQIRNMLLELQDFGLVDILIGR
                     GGSIITSKGVEFLKNINRSNKLNS"
     gene            68561..68962
                     /locus_tag="PC465_000953"
     CDS             68561..68962
                     /locus_tag="PC465_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648278.1"
                     /translation="MKKCLYCNRDIKSPNNKLAIKYDDNMNIYPCRAECKEKIEEYIA
                     KKPTYKFINILEVLLGVGGIFCFLSKWTIAAQVVLGIDALVIFLFPLAGFKMNGKLSM
                     EQTKNQSRSIAISILAFIVIITVLYFKQVGK"
     gene            69005..69298
                     /locus_tag="PC465_000954"
     CDS             69005..69298
                     /locus_tag="PC465_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HDF2648279.1"
                     /translation="MEERKLAPNNEREALIKRLKRIEGQVKGIQKMVEQERYCVDILV
                     QISAIRSAINRVGTIILENHIKGCVAESIKHDDADKTEEMIKELMDTINKFTK"
     gene            69313..69753
                     /locus_tag="PC465_000955"
     CDS             69313..69753
                     /locus_tag="PC465_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HDF2648280.1"
                     /translation="MNQQGFIMEIVDDRTAKLKMQRHSACAACGKCATTNSAESKEIL
                     VEVDNTIGAKVGDHVEVSMDNMNVLKAAVMAYIIPLIALLVGTIGTYYILGAIGMTTG
                     VEAISGLVGICLTIICYLYLKKNDKKFRDSREFIPVITRILIDL"
     gene            complement(69845..70318)
                     /locus_tag="PC465_000956"
     CDS             complement(69845..70318)
                     /locus_tag="PC465_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF2648281.1"
                     /translation="MTDMSMILHFLFSGVATAGFAVFFNAPLYLLLPAGVTGGIGWIV
                     YVYLFNFTTNAVFAGFIAAALVSACSETLARKLKQPAIVFVIPGILPLIPGIGLYNTM
                     LSLIQKNYSLAMSKGTDALFLSAAIALGVLVVTSFVRTLNLLKIRKNFIPYRKSK"
     gene            complement(70318..71106)
                     /locus_tag="PC465_000957"
     CDS             complement(70318..71106)
                     /locus_tag="PC465_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF2648282.1"
                     /translation="MNQNEELEYKKNILKLALFVGELMIKNGAETSRVEDSVLRICRS
                     RGFYHVNIFTTPTVIIISDEKFDGFSFMKTIQSRGINLNKISLLNSFSREFVSDKEYD
                     IDNAIARLYEIQDVKPYPLWLFYSCTGIASACFACLLGGNYVLNFILTFIIAIFAAIT
                     YDKTMKISAISAFSCLVSSFLIALSGVLLVEIGILDDPKMLIVGAIMPLLPGVAFIKA
                     IRDLISGNLISGISRAFDAAMIIIAIASGVGFVLDTWYRIGGPF"
     gene            71434..72678
                     /locus_tag="PC465_000958"
     CDS             71434..72678
                     /locus_tag="PC465_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDF2648283.1"
                     /translation="MFENLKKADPEIYESMKRELKRQQRNIELIASENIVSVPVMETM
                     GSHLTNKYAEGYSGKRYYGGCEYIDEVETLAIDRIKKIFGAEHANVQPHSGANANIGV
                     YFAMLKPGDVVMGMNLSQGGHLTHGAPVNISGQYYKFYEYGIDKDSGLIDFDEVRKIA
                     HEVKPKMIVAGASAYPREIDFKKFREIADEVGALLMVDMAHIAGLVAAGLHQNPCEVA
                     DFVTTTTHKTLRGPRGGVILCKEKYAKDIDKAIFPGIQGGPLEHIIASKAVCFKEALS
                     DEFKEYQVQVAKNAKALAEELIKRDFKLISGGTDNHLILLDLTNKNITGKAAEKRLDD
                     AYITANKNTIPFDPNGALVTSGIRLGTPAVTTRGMKEEDMAIIAEAIDLCLTYDEESK
                     ARTLVVGLTEKYPLYEEYNIMD"
     gene            73001..74098
                     /locus_tag="PC465_000959"
     CDS             73001..74098
                     /locus_tag="PC465_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-diphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDF2648284.1"
                     /translation="MKVLILTGKFGMGHYSASNSLSEDIKAKFDNSEIIIKDIFEYIM
                     PNYSDKMYKTFSILVNRGSSLYNLFYKCAENGKKDIKFTFSDYFLNKLDTLLHEVQPT
                     VVISTFPFCSQLVSRYKEKYNSNLPLITCITDISSHSEWISKNTDCYLVASKSTKEEL
                     VFKGIDESKIKVNGIPVKKEFKRIEHVNHSTKKNILIMGGGLGLLPKSEQFYKELNSL
                     EGVKTTVITGNNKKMYYKLYGRYENIEVVGYTNEVYKYMKDSDLIISKPGGITLFETI
                     YSELPILAFNPFLQQEIDNASFILNNEIGRILGKNKKYYVDEIKDLIYDDATLKEMSS
                     NMKELKKQFDNNTLENILFSLDEQGACRECM"
     gene            74089..74787
                     /locus_tag="PC465_000960"
     CDS             74089..74787
                     /locus_tag="PC465_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2648285.1"
                     /translation="MYVVGLIIVVALIFLVHSIIPTYYNKLLNKEVLKNMAGENEIAL
                     TFDDGPDKRYTEKLLDVLKENDIQAMFFVVAKNAEKEPEIIKRMLRENHIVGLHSLEH
                     RNAWLYSYSYVKKDFIESTNIMKNLGVDVNYYRPPWGHTNIFSNSFVKKYNLKMTLWD
                     VMAEDWEKDSTVDIIINKLMSRTKENSIICLHDAGENSGGAVGAPERTIEALKIAIPK
                     LKASGLKFVTPERM"
     gene            74790..75854
                     /locus_tag="PC465_000961"
     CDS             74790..75854
                     /locus_tag="PC465_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDF2648286.1"
                     /translation="MISKTEKKNKCLGSVAFLVLLMGITGYFVFRGQSVESLIKSLKG
                     ASPMFILIGFAMMFIYVACEGINIYLGMKALNQKTTLLKCMGYAFIGFYFSSITPSAS
                     GGQPAQVYYMKKDDINISYSSLILLVIVVIHQVVILAYSGIMFIMEREFILNNVSGMN
                     ILLIYGVITNVALVIGVIAIIFSKKLVNNFIISITNLLGKLRIIKDVESSRKVIISQI
                     EEYVKGAQYIKQNPKLVVQILVITIVQITAMFLVPFFVYKAFHLSTYTVFEILAIQSL
                     LNIAVSSLPLPGAVGASENSFMTLFKIFFPGHLLVPAMLLSRGISFYAFVAISGLICI
                     VVHVKSSEKVKAVKKVAYVR"
     gene            76037..76741
                     /locus_tag="PC465_000962"
     CDS             76037..76741
                     /locus_tag="PC465_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2648287.1"
                     /translation="MNKEIPKKILVADDNPEIREIVEILLTGEGYEVIMATNGEEAVN
                     LVDSTIDLIILDVVMPVKTGFVACNEIREKTTAPILFLTAKTQDSDKVIGFSAGGDDY
                     LSKPFSYSELISRVKSLLRRYYIYQGKEKEREPNILKTKELCVNLDTQDVTLNGEPVF
                     LTTIEYSILILMLKNRKKVFSSENLYETIWDEQYFYTANNTIMVHIRNLRKKLEKDQK
                     NPQYIKTAWGKGYYID"
     gene            76734..78056
                     /locus_tag="PC465_000963"
     CDS             76734..78056
                     /locus_tag="PC465_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2648288.1"
                     /translation="MINKIKPSKLGVILLIYVVISAAVAFILNIPFYSAVESIVKDVS
                     EGKVYFKREVNQLMDNFQTYVNNNGIRADDGDDIAKWNSDNWFVSMKIYKGNKVFYDT
                     LYYPNEVPDKSEENEFYSSPMARNYEIQFSDIKANIVVVALFRFRFQNFIEAISITFM
                     ALTFIITFLLLFSRKIKYLRKIEMGIKIVESGSLKYRIPVKGNDELSSLASSINEMSH
                     TLENQLIKEREMKNKNKDIVTSISHDVRTPLTSVICYLDLIKDHKYNSPEQLEQYIKN
                     VRSKAYQIKDLTDDLFTHFVNSGEEVSKGYEKINANEFIFQLLLDSSYTLEEKGFHIT
                     IENELYNQYHIYVDVTQFRRIFDNLCSNIIKYARKDKPIVFLIKVEDSKLLIIQKNRV
                     SNFSKNVESFGIGIKNCEKIVAYHNGSINVNSDDKEFAIEISIPAKES"
     gene            78222..79595
                     /locus_tag="PC465_000964"
     CDS             78222..79595
                     /locus_tag="PC465_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648289.1"
                     /translation="MVLTGAHYIYILFMVIILITMIMKKDTIVPCILGVFFMGLFFEK
                     NIFGAITAVFNSFIISLNELGPIILIIAIMVALSKALEANNAIQYMVRPFSRVIKNSN
                     TAFFVTGFVMLVLSWFFWPTPAVALVGAVFLPVAMRAGLPAIGVAVALNLFGHGLALS
                     TDFVIQGAPSITAGAAGVAVSYVINDGMILFWVMGIVTISMAFYTLKRDINKGMFREE
                     LKGFESEEVEEFNGKSKIATILVALGFLADIIAMYVFDLKGGDASALLGGTAVFLIII
                     INVINFGKDSLENVCENIIDGFVFGIKIFGAIIPIAAFFYMGEVAPLTGVFGKVLAPG
                     SQGLLSDIGIALSQTIPLNKFAVSGIETVVGAITGLDGSGFSGISLVGSLASVFGTAI
                     NASVGALAALGQISGIWVGGGCLVPWGLISASAICGVSPIELAKRNFVPVITGLVVTT
                     IVAMFII"
     gene            complement(79967..80905)
                     /gene="pdaA"
                     /locus_tag="PC465_000965"
     CDS             complement(79967..80905)
                     /gene="pdaA"
                     /locus_tag="PC465_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HDF2648290.1"
                     /translation="MFRKVLHYLTLLSISIFFIVGCSNSQNNQNENQNKETQLQEDKE
                     KIDSGKDTSNVIVSDGTDKPSKATTNNDNNKLDVSSLDNTTLDWFYIPNNKHKTPEVN
                     TDIEFKFSDYDALYNGPTKDGQKTLYLTFDEGYENGYTTKILDTLKQNQVKAVFFVTA
                     PYIKENKDLVKRMVSEGHIVGNHSKTHPSMPTKTSNLKNFNDELYDVEKLYKDVTGKD
                     MVKFFRPPMGKYSEKSLAMTKNLGYKTVFWSFAYRDWDTDKQPSHEEATQKIMDNLHD
                     GSILLLHAVSKTSTEILNDFISNARKLGYEFELLEY"
BASE COUNT        31845 a         8865 c        13988 g        26480 t
ORIGIN      
        1 aatttcaaat aatgctgtag attctaaact tatgaatagt aggattaaat caatagatat
       61 aataagaggg ctatcaatag ccctcatgat agtctgcaat aatcctggga cttggatgag
      121 aatgtatcct caattaagac atgctgtatg gcatggtgta acacttgcag attttgcatt
      181 tccttttttt gttatatctt taggtgttac aattccaata tcaataaata gtaagataaa
      241 aaataataaa tccacactga gtataatact tagtatattc aagagaagta tcttattgat
      301 attatttgga tttttcttaa attacctagg aaatcctgat ttagatactg taagaatact
      361 tggagtactt caacgtatgg gattagtcta ttttgtgact agtttagtat atttactact
      421 aaaaaaatta aatgttggaa gtactgctac aataattact tttctatgta tatctacatt
      481 tataatagtt gggtactaca tattagcaaa accttatgga tttgagctag aaggttctct
      541 tgcacagtta gtggatttac atttcttcaa gggacatttg tacaagccag aatttgaacc
      601 agatggtttt ttaactagta tagtagcaat ttcttcaggt atgttgggat gcactatggg
      661 atgtgtactt ttaaaagaaa atctaggaga atataaaaaa ttctttaaaa tactggttat
      721 gagcataatc ctgctaatag gtgcttttat ctttaatcag tattttccat ttaataaaag
      781 attatggtct agctcatttg tacttttaat ggctggcagt tatggtatat tactgtcaat
      841 attttatttt atatgcgaca tcaaaaataa aagtaaaata tttaccccaa taatagcact
      901 tggaagtagc cctattttta catatatgtg ccttgaaata ttaagtcatg ttttttggaa
      961 tgttccaaaa cttacgaaca aagtcgatta tccaactacc ttggtagagt ggactacata
     1021 tgaacttata acaccttggg caggtacaac ttgggattct cttatatttt ctttattgta
     1081 tgtcctattc tgggttatag taatgtctat aatgtacaag aaaaaaatat ttattaaaat
     1141 ttagtgcaat atttttagat gataaagtct ttgatttgtt caaatatacg gaaactatca
     1201 gatataatca aaatttctcc tcgataaaat ttaaaaacca tgccataaaa gattacaaaa
     1261 agtttacaat ttgtaatttt ttgtgctata atgaaaaaag atttacataa tattgaattt
     1321 atgtaatata aaacaagctt aagatgtatt aaaaaagatt taaagattta aagaaccaaa
     1381 aaattagggg ggatatgatg aaaaaaacaa caaaattatt ggcaacagga atgttgtctg
     1441 tagcaatggt ggcaccaaac gtagctttag cggctgaaaa tactactgca aatacagaat
     1501 ctaattcaga tattaatata aatttacaaa gaaaaagtgt agtgttagga agtaaatcta
     1561 atgcaagtgt aaaatttaaa gaaaaattaa atgctgattc aataacatta aattttatgt
     1621 gttatgatat gccacttgaa gctactttaa attacaatga aaagacagat tcatatgaag
     1681 gtgtaataaa ctataacaaa gacccagaat acttaaatgt atgggaactt caaagcataa
     1741 aaataaatgg taaagatgaa cagaaagttt taaacaaaga agacttagag tctatgggat
     1801 taaatcttaa ggattatgat gttacgcaag agtttataat aagtgatgca aattcaacaa
     1861 aagcagtaaa tgaatatatg agaaaaactt ctgcaccagt aaaaaaactt gctggagcta
     1921 ctagatttga aactgctgtt gagataagta aacaaggttg gaaagatggg tctagtaagg
     1981 ttgtaatagt taatggagaa ttagcagcag atggaattac agctactcca cttgcatcta
     2041 catatgacgc accaatatta cttgcaaata aagatgatat accagaaagt acaaaagcag
     2101 agttaaaacg tctaaatcca agtgatgtaa taattatagg tgatgatggt tcagtttcac
     2161 aaaaggcagt gtctcaaatt aaatctgctg taaatgtaaa tgtgactcgt attggtggag
     2221 ttgatagaca tgaaacatct ttacttatag caaaagaaat agataagtat catgatgtta
     2281 ataaaatata catagcaaat ggatatgctg gtgaatatga tgctcttaat atttcatcaa
     2341 aagctggtga agaccaacaa cctataatat tagctaataa agattctgta ccacaaggta
     2401 catataattg gttatcttca caaggtttag aagaagctta ttacataggt ggtagtcaaa
     2461 gtttatcatc aaaaattata gaccaaatat ctaaaatagc aaaaaatggt acttcaaaaa
     2521 atagagtttc tggagcagat agacatgaaa caaatgcaaa tgtaattaag actttctatc
     2581 cagataaaga gttgagtgca atgttagttg caaaatctga cataatagtt gattcaataa
     2641 cagcaggacc tttagcagct aaattaaaag ctccaatact tataactcca aaaacttatg
     2701 tttctgcata ccatagtaca aacttatcag aaaaaacagc agaaacagta tatcaaattg
     2761 gtgatggaat gaaagatagt gttataaatt ctatagcatc tagtttatca aaacacaatg
     2821 caccaacaga accagataat tcaggttcag cagcaggaaa aactgtagtg atagacccag
     2881 gccatggggg ttctgattca ggggcaacaa gtggattaaa tggtggagca caagaaaaga
     2941 aatatactct taatacagca ttagcaacta ctgaatattt acgttcaaaa ggtataaatg
     3001 ttgttatgac tagagataca gataaaacaa tggctttagg agaaagaaca gcattatcaa
     3061 atactataaa gccagattta tttacaagta tacattacaa tgcgtctaat ggagctggta
     3121 atggtgtgga aatttattac aaagtaaaag ataaaaatgg tggaacaact aagactgcag
     3181 catcaaatat cttaaaaaga atactagaaa aatttaacat gaaaaataga ggaatcaaga
     3241 caagaacact tgataatgga aaagattacc tatatgtgtt aagaaataac aattatccag
     3301 caatacttgt tgaatgtgca tttattgaca ataagagcga tatggataag ttaaatactg
     3361 cagaaaaagt aaaaacaatg ggaactcaaa ttggaatagg aatagaagat acagtaaaat
     3421 aaaatagaaa atattaaagc aaaacatatc atctcctgtt ataatgtaaa atataacaag
     3481 agatgatata tttttgtaaa gaatcaaatt gtttacaatg atgtttcttg tattgataat
     3541 ctgctcatta ttgagtataa tatagaaata agtcaaaaat aagatagaaa taagttgaaa
     3601 ttaagaatta aaaaaatttt tattccaata tggaggtaac tatgtctgga tatactaatg
     3661 atgagtgtga aatacctaaa attaaaagct atccaggggc agataaagaa attgcaagtg
     3721 agattgacta tagcatagta aaaggaacag ttttattcga cttgtaccaa agaattatgg
     3781 atttagtttt atctataata ggacttgtga taggtttacc tttaatagca atatttggaa
     3841 ttcttattaa aatagaggac aaaggaccaa taacttataa gcaagaaaga ctaggaaaat
     3901 gcgggagaag attctatata tataaattga gatctatgag aacagacgca gaaaaatttg
     3961 gcgcacaatg ggctgaaaaa gatgatccta gaataactaa ggttggaaag tttattagga
     4021 aaactagaat tgatgagatt ccacagctgt ttaatatatt aaagggggac atgggcttaa
     4081 taggtcctag accagagaga ccgaacttta ctgttcaatt taatgaggaa atacctggat
     4141 ttatcaacag gctcgctata aaacctgggc ttacaggttg ggcacaagta aatggtggat
     4201 acgaaatcac tcctgaagaa aaacttaaag aagatattta ctatataaaa aataggagta
     4261 tattacttga ctttaagata ctctttaaaa ctgttaaagt agtattgaca ggagacggag
     4321 ctagataatt ttaaaatatt agattactaa tcaatgaaaa agctctttaa aaagagcttt
     4381 tttattgtca aaaaatacaa aaaagaaaag gaatgagaac ttatgattaa aaaaatttct
     4441 actatattat cgttagtttt gttaatctct atttctagta cgataggagt atttgcagat
     4501 gcaaatccca aaagagagtt gatagaaggg agtataccag agatttcgac agaattaaat
     4561 aaaagagcat ttaaggattc taaagaagta attcttgtaa atgaagagtc aattgtagat
     4621 agtataagtg caacaccttt agcatatgca aaaaatgctc caatagttgt aactaagagt
     4681 aaaaatcttg gtagagtaac aagaaattat ctaaaagaac taggtccaga gaaggttacg
     4741 atagtaggtg gtttaaaggc agtatctaaa gatgctgaac gtaatataga aaaaatggga
     4801 atgaaagtag aaagaataag agggaaagac agatatgata catctttaaa gatagctaga
     4861 gaaatgtata gaacagtagg atttgatgaa gcatttttac ttagctcaac aacaggatta
     4921 gagaacgcca tatctgtata ttcttatgcc gctaaaagtg gaatgccaat aatatgggct
     4981 aaagatgaag ggtttgagga acaaattgat ttcttaaaag gcaaaaacct taaaaaaata
     5041 tatgcattag gtgattcaaa agagtttatt gcagagattg attctaactt aaaaaatata
     5101 gaaggaataa agcaaataaa taagtcaagt acaaatgttg atttaataaa gaagttttat
     5161 gatgaaaaag atataaagaa aatctatact gctagattag actttggtag tagatctgat
     5221 gtaaacgaat atatttcttt gggagtagta tcagcaaaag aaaatatgcc aatactgatt
     5281 tgtagtgata acttaagtcg tgcacaagat aaattcttga aagatagcaa tataaatgat
     5341 gtagttgaag ttgggtatac agtaggtgat tatagtctat ttaagagcat atttaatcta
     5401 acattcttat cttgtatagt attaatacta ttattactat tgattacatt tagggcactt
     5461 agatatgagt cgaaatagtt tttgatttat aaggaagctt ttcataggtt aaatttactt
     5521 aattagaata atgtttataa gcagttttaa aagttctact tttagagttt aaattagata
     5581 aggagaaaga agatgtcaaa aacagctaaa gcagcattgt ggattatggc agccactatg
     5641 ttttcaaaag tattaggttt ccttagagaa cttgtacttg caaatttcta tgggacaggt
     5701 atgtatgcag acgtatttgt attaacatta aatatacctg gtttaatcat agcagtcata
     5761 ggctctgcag ttgctacaac ttatatacct atgtactttg agacaaagaa aagactcgga
     5821 gatgaaggtg ccttaaaatt tactaataat gttttaaata tatgctatat aatggctata
     5881 gtaatagcta ttattgggct tttatttaca gagcaatttg ttacagtatt tgcagcagga
     5941 tttagaaacg accctgctaa gttccaagca gcaatattat ttactaaaat aatgatttca
     6001 ggagttttat tcctgagtgg aagtaagata tttagttcgt ttttacaggt gaatgacagt
     6061 tttgtaattc ctgggcttat aggaatccca tataatatta taataatagc agcaatagca
     6121 ctaagtgcag gtaaaaatgt atggatactg ccagcaggag cattattggc tatggcgagt
     6181 cagctattgt ttcaactgcc atttgcgttt aagaagtcct acaagtataa gccatatata
     6241 aatttaaagg atgagtccat aaaagagtta gtcaacctag tattgcctat gttggtagga
     6301 gtagctgttg gacagttaaa tatatttgtt gaccgattat tggcaaccac tttgggtgat
     6361 ggaaagttgt ctgctcttaa ctatgcaaat aggctaaatg agtttgttat ggcattattt
     6421 gttacatcta taataacagt tatatatcct aaactagcaa aaatgtctgg taaagataat
     6481 aaagaaggat ttataagcac tattgtaaaa tcttcaaatt gtattatatt ggtggtgctt
     6541 cctatatcta taggagctat tatattagca gagcctcttg ttagaatatt attccaaagg
     6601 ggtaaatttg atgcgttatc aacagacctt acatctatag cgcttagatt atattcacta
     6661 ggtttattgg cttgtggagt aagagatgtc ttatataggg cattttactc tctttcagat
     6721 acaaaaacgc caatgataaa tggaagtata gctttaataa taaatatagt tcttaattta
     6781 atattgataa gaccattggg tcatgcaggt attgctatat caactagtac atcaaacata
     6841 attacagtta tattattatt tatatctctt aaaaagaaaa atggatattt tggaggggat
     6901 aaaattataa agactggtct aaaaagtttg gtagcatctg gtgtgatggc agtagctact
     6961 ttattgatat ataataatct atatgcattt atgggttcag gaacaattaa agaaattata
     7021 tcagttggag ctggagtatt aggtggagct tctgtatata ctgtattgat agttttattt
     7081 aaggtagaag agatggattt agcttttgaa tttttaagaa aaggaaaaca aaaactactt
     7141 agaagataga taattacctt gaaattttaa attagagtca gaaaggatga aaatatggat
     7201 tataagaata attatgagat gtggttaaat tctccttatt ttgatgaaca aacgaaaaat
     7261 gagctattaa gtataaaaga tgatgaaaaa gaaatacaag atagatttta taaaaattta
     7321 gagtttggaa caggtggttt aagaggtata ataggagcgg gaactaatag aatcaatatt
     7381 tatactgtta gacgtgcgac actgggcgtt ttaaattata tcatgaaaac tcaaggagaa
     7441 gaaggtaagc aaaagggaat agttatagca catgatagta gatacatgtc tagggagttt
     7501 tgtatagaag tagcaaagac tttaagtgct tatggtgtaa aggcttatat ttttgaagaa
     7561 ttaaagccta caccagaact ttcttttgct gttagatatt taaagtgtgc tatgggaata
     7621 gtaataacag caagtcataa tcctaaagaa tacaatggat ataaagtata tgactcagat
     7681 ggtggtcaaa tctgtataga tatggcaaat gatataatag cagaagttaa taagattgat
     7741 gattacagta ctattaaaag tatagatttt aaagaagctt tatctaaaaa tttaataact
     7801 atattagata atgaagtaga tgatgagttt ataaaagctg ttaagaagca agttttaaga
     7861 caaaatataa tagatgaata cgggaaaaaa ttaaaaataa tatatacacc tattcatggt
     7921 acaggaaata agccagtaag aaaagtctta aatgaatgtg gttttgaaaa tgtaatggta
     7981 gttaaggagc aagaattgcc agattctaat ttttcaacag taaagtatcc taatcctgaa
     8041 gaaaagtcag tgtttaatat agctattgaa atggcaaaga ataatggcac tgatttgata
     8101 ataggaacag accctgattg tgatagagta ggtatcgttg taaaagattc aagtggtgaa
     8161 tatgtagtct taaatggaaa tcaagtcggt tcacttttag ttagatatat attagagagt
     8221 ttagttgaag aaaataaact tcctaaaaac aatcctacaa taataaaaac tatagttaca
     8281 tcagaactag gtgcaaaaat agcaaaggct tataatgtag attgtttaaa tactttaaca
     8341 ggatttaaat ttataggaga aaaaataaaa gcgtttgaag aaagcaatga tagaagtttt
     8401 ataatgggat atgaggaaag ttatggttac ttaattggaa ctcatgctag agataaagat
     8461 ggtgttgtat cttcacttat gatatgtgaa atggcagcat actattcttc aaaaggtatg
     8521 aacttgtatg aagctttgat agatacatat aataaatttg gatactacaa agaggactta
     8581 aagtcagtaa ctttaaaagg catagatgga ataaaaaaaa taaaagagat gatgctttac
     8641 tttagaagtg ttaaaataga taatgtggct gatgtaaaag tagataaaat tttagactat
     8701 aaagatagtg ttgatgattt acctaagtca gatgtactta aatttttact tgaagatggc
     8761 tcttggatag ctataagacc ttcaggtaca gaacctaaaa ttaaatttta ctttggagca
     8821 aattcagaca atcaagaaga tgtagaattt aagttgaaca atttaatatc ttatatatta
     8881 aatgtagtgg attctatata aaaagctaag gggagataaa caatgaaagt atacaatgtc
     8941 ataatggctg gaggaggagg aactcgtttc tggccactta gtagacaaga agtacctaaa
     9001 cagcttataa atttaagtgg agaagatgct ttaataaacg aaactataaa cagaatagat
     9061 tctctagcaa aaaaagatga tttatttata gtaaccaatg agaagcaatt ggaagcttta
     9121 aaggatatag taaaagataa atgtttggat agtaatatat tgccagagcc atgtgccaga
     9181 aatacagcag cagctatagg ctttgcagca tttaacataa tgaaaaaata tggtgatggt
     9241 gttatgtgtg tatatccagc tgaccattat ataaaagatg aaaaagaatt taaatctatt
     9301 ttggaaaaag ctatctatat agcagaaaat aatgataaac tagtaactat tgggataact
     9361 cctacatttc catcaacagg atatggatac ataaatttta atagagaaaa tactatagaa
     9421 gatgttgcat atgaggtagt ggagtttgta gaaaaaccaa actatgaaat tgctaaagaa
     9481 tatgtaaact ctaaaaagta tgtatggaat agtggaatgt tcgtatggaa ggtatctaaa
     9541 atactagaag attttaagag atacttgcca aaagtatatg aaaaattaga agatataagt
     9601 aaatacttag gaacaaaaga agaaatggaa aaaataaaag aaatataccc aactatacaa
     9661 tcaatctcta tagattatgg tattatggaa agaagtaatg atgttatagt agttcctggt
     9721 gattttggat ggaatgatgt tggttcttgg gattctctag gtgcaatata tccaactgat
     9781 gatgaaggta atatcaaaag aggtgaaaat attactatag atactaaaaa ttcaattata
     9841 tattcagatg acaaattaat atcgacaata ggtattagtg atttgatagt agtatctaca
     9901 aatgatgcag ttatggtttg tagaaaagat aaagctcaag atgtcaaaaa aatagtagag
     9961 cagttaaaag aagaagatag acaagaatat atgtaggagg tgttcatttg attcctaaaa
    10021 aaatacatta tgtatggttt ggtggtccaa aaggaaatat agaaaatata tgtataaatt
    10081 cttggaaaga aaagcttcca gaatatgaga tagtagagtg gaatgaaaaa aactttgata
    10141 tagagaaaga aataaaagga aataagtttt tggaagaatg ttataaaaga aaactttggg
    10201 cattcatatc tgattataca agaataaaag tactctatga acaaggtgga gtttatatgg
    10261 atacagatat gcaaatatta aaggatataa ctcctctttt agaaaataat aggctaatct
    10321 gtgggtatga agatgataga gagtatataa atggtgctat aataggtgta gaaaaaggac
    10381 atcctttttt aaaagactta ttggagtact atgaaaaaga agtacttact tcttcattgt
    10441 ttacaatacc aaagataatg actcatctta tggaaaagaa ttataagaag attgacctaa
    10501 ataattatga agaaggaata cgtgtttacg acaaagaata tttttatcct tttggattta
    10561 aagaagactt tacaccagaa tgtataacag aaaacacttt tgggatacat tggtggggaa
    10621 aaagttgggc taaaaagaga aattatttct tagaaagcaa acacttaaca ggtgtaaata
    10681 agatatggaa gtgttgtaaa atatttgcaa gtaatacttt acgaagctaa aagggagaaa
    10741 gtaaaatgaa gactttaaat gatgatagaa atattatgat tagaaaatat ctttatatat
    10801 ttgttttgtt tatcatatta cttagaaagt atatgatatc atttattgac ccaaatatgg
    10861 atatagggat gattaaatca gcgttatttt attcttcaat aggaatacta atgctacttt
    10921 ttttatttga taagagaaaa agtataacag aaatggtact agttggagtt tgtgtcttac
    10981 tttatttatt aaatagggaa ggagctatat tattaatcgt tttattagct gtatcagcta
    11041 agcaaataga tgataaattt atagttaaaa attatttaat aatatcggca tgttttttaa
    11101 tggtagctat attattattt aatctatttc cttcattaat atttaatcag gaagtccact
    11161 atagatatat agaaaaaata gatatgcttg ttacaagaat ggattttgga cttggtaatc
    11221 caaatagtgt attttatcat atggttacta tatatgcagc atatatattc ttaagatata
    11281 aagattataa taaatgggat agaataattt tatttggttc tgcatttttt gtttatcaaa
    11341 ccacatatag tagaactgga tttttcacta tattagcagg attaatattt gtagaaataa
    11401 taagatggat agatataaaa aaaataaaag gactaccaat gctcctaaag acattaccga
    11461 taatacttac tttatttagt gtaattattg gtaaagtatt tgataaaagc actttattaa
    11521 atagattatt agcaagtaga cctaagttct ggcatgtata cttggctgaa aaggggaact
    11581 ttctaaaacc ttttggaaat tcatatagtc ctgctataaa agcaactaat ccattagata
    11641 gttcttatgt atatataatt agtgtactag gagtagttgc ttgtatatta tttatgtatt
    11701 tgatgtataa aggaatagaa agctttatag aaaaagataa aaaagcatat ttagtagctt
    11761 tatttatatt tttactatac tcttttgcag aaaatttatt attagaagct tcatttagtt
    11821 ttgcagtagt attactaata aaagaagtga tattaaatga taaaagggaa atagatttgt
    11881 ggaagatgaa aagtaggagg tagtaatgtt aatatcatta ataatgccaa cattaaatag
    11941 atatgatgat atatacttac ttatggacag cttagaaaat caaacttaca aaaactttga
    12001 acttatagta gtagaccaaa atgataatag caaagttaaa gaaatagttg ataaatacat
    12061 tgataagtta gatataaagt atataaaaag ctctaaaaaa ggattgagtt ataacagaaa
    12121 tgtaggcata gacaatgctg tagggcaaat tataggtttc cctgatgatg attgtgtcta
    12181 cgaaaatgat acattagaaa aagttataaa tttctttaat aaaaataaag attataaaat
    12241 atacagttgc aaaactatgg attcaaataa agttgatgca tttaagaaaa tgtatgatgg
    12301 aacttgtgat atcacaagtt ccaacgtttt ggatactata acatccataa ctttttttat
    12361 tgattttgaa ggtaaagact atacaagatt tgatgagaaa ttgggtgttg gtggagagtt
    12421 tggtgctggt gaagagatag attatgtttt aaacttattg agtttaggtt ttaaaggaaa
    12481 atactttgga aatgatataa tttaccatcc tgcaaaaaaa cattctaaat ctaaagaaaa
    12541 gtatcaaaaa gattataact atggaagagg ctttggagcg ctttgcaaaa aggaaatagt
    12601 ctatagaaaa aattataagt ttgcaaaagt tatggtatca aaacttgtaa gaaatatagg
    12661 aggtcttata ttgagttcca atagagatta tcatagtgcc actataaaag gaagaattaa
    12721 tggatttaga cagtacaagt tataatgagg atggtgttta tggacaaggt taaattttta
    12781 ataaatatgc ttttggcttt ttttatatat ccatttaata agcataagtt taatggtaga
    12841 gatatctggc ttataggtgg acattcaggg gatatataca atgataattc aaagtttttt
    12901 tatgagtata tgctaaaaga acataatgat gtagaaactt attgggtagt aaataaagac
    12961 agtaaagtat ttgataaaat tccaggcaaa aaattaataa gaggaagtgt agaaaactat
    13021 ctgtattatt acaattcaaa agctatagta ttttcacatg caccatcagc agatatagca
    13081 ccatacaatt ttgctgtacc tgttcttaat tattttcata aaaaaacgat aaaagtgttt
    13141 ttaaatcatg ggactataag ttttaaaaaa agaaaaccta tgaacaaaaa gttcaaaaat
    13201 attatagata acctatataa aagctataat atagttacag caagttctga atttgaaaga
    13261 aatgttatgg taaatgattg gggaatgtta gatgactcag tttatataat tggaaatgca
    13321 agatatgaca atttaccaac aaatgaagtt gcacaaactc gagatatatt atatactcct
    13381 acatggagag attggataaa atttagttca ggaaaattta cggatacaga ttattttaaa
    13441 aatataatga attttttaaa tgatgacaaa ttaaataaaa tattagatga gaaagatata
    13501 aatgtaaaaa tttatatgca tcatcttatg catgagttta tagatgatat aaaagaaaat
    13561 ataacaggaa aacgaattgt gtttttagat aaaggggtaa ctctagcaaa tgaaatcaga
    13621 aaatcagctg caaatataac tgattattca agtgtagcca tagacttttt gtatatgaat
    13681 agacctatct tgttttacca attcgatttg gatgaatata tggaaaaagt tgattcatat
    13741 atagatttaa aaagtgaaat gtttgggtct ttggcttata ataatgatga agccgtgaat
    13801 aaacttattg atattattga aaataatttt gaggttatgg ataaccaaaa aaatgaaaga
    13861 aataagtttt tcagatataa tgataataag aactgcaaga ggatatatga ttgtgtatta
    13921 agtaaaatta aataaatatt ttataaatga tgaggaaggt aatatgaaga agaatttagt
    13981 atctataatt actcccatgt ataattctga aaaatttatt gaagcaacca taaaatcagt
    14041 attaaaccaa acttatcaag aatgggaaat gttaattatt gatgattgct caacagataa
    14101 tagtcctaat atagtcaaat cttatatgca acaggatagt agaataaaat gtataaagac
    14161 tgagactaat aagggtgtct ctaatgctag aaatttagca ctaagtaagg caacaggaca
    14221 atttatagct tttttagata gtgatgacca atggaatagt agtaagttag aaaaacaagt
    14281 aaattttatg ttagaaaatg actatgtaat ttcatttact tcatatgaac tgatggatga
    14341 aaatgataaa aaattaaaca aagtaataaa agttccacct aatgtagatt atagaagatt
    14401 attaaaagga aatatcttag gatgtcttac tgttgtgatt gataagtcta aattggattt
    14461 tgaaataaga atgagtggtg taagacatga agattatgtt ttatggttat cgatattgaa
    14521 aaaagggcat attgctcatg gaataaatga agttctagca ttatatagaa aatctagcaa
    14581 ttccctaagt ggtaataaaa taaaagctgc tatgtggact tggaatatat atagaaatat
    14641 agaaaaaata cctttataca aagctatata ctactttatt aattatggaa taaacggaat
    14701 caaaaaaagt tagacagaga ggaagattta attaatgtat aaatataaat ttactgtatt
    14761 tactccgacg tataacagag ctcatttact tgaaaatttg tacaatgatt taaaagctca
    14821 aacttatgat ttcaatgatt ttgaatggtt gattgttgat gatggaagta gcgacagtac
    14881 taaagagtta gttgaaaaat ttatatcaga aaataaatta aatataagat atatatacaa
    14941 agaaaatgga ggaaaacata ctgcaataaa tctaggtgta aaaaatgcag atggagagct
    15001 atttttcatt gtagatagtg atgatggttt aattaaagat tctcttgaaa ttgctaatga
    15061 tgagtgggat tctttagaga ataaagaagg atttagtgga gttgttggac tttgtgtata
    15121 tccaagtgga gatttgatag ggacagaaat gcctgaagat aagaaaatat gtcactttgc
    15181 agacctatat tttaagtatg gcgttaaggg agataaaagc atagtatttg taactgatga
    15241 gcttataaaa tttccttttc cagaaagaaa agaagtgaga tttttaccag aaagtgcagt
    15301 atggaatgaa atgtctaaat actataaagt tatatgtgta aataaaccta tgataataag
    15361 agattatttg gatgatggtt tgactaagaa tatattaagt aaaaatgcat taagaggtag
    15421 agcattagag tttttatatt taataaatca aaatacatat ccattaagta gatatccata
    15481 tatgtggata aaaaattaca taaatttagc cagatactca ttgttgtctg atagtcatta
    15541 ttttggtgaa ttaagaaaag tatctgataa attgttgtat ttagcattat tcccattagg
    15601 atattacaaa tatattggac aaagaaaatt agtatctaag taaacttgtt ggtatagtac
    15661 tgctagttgc tatataagga gagtaaaaat atgaatgagc ctttagtatc gataattact
    15721 cctgtttata attcagaaga gtttttatca gagacgataa agtcaatcca aaatcaaact
    15781 tataaaaatt ggcagctttt attagtggat gattgttcta aggacaattc aagtgaaatt
    15841 ataaaaagtt ttcgaaaaga agatgctaga ataaaatata taaagcttga aaaaaattct
    15901 ggagctgcag tatctagaaa tgttggtatt aagaatgcgg aaggtcgatt tattgcattt
    15961 gtagatagtg atgatttatg ggatagtaga aaattagaga ttcagataga atatatgtta
    16021 aaagaaaatg taggtttttc ttttacatct tatagatata tgagacaaga tgggtcaaaa
    16081 acgaataagg ttgcaagagc tcctaagaaa attgactatg aaggattact tagaaatact
    16141 ataataggat gttctacagt ggtcattgat aaggagattg taggagagtt cagcatgcct
    16201 ttggtaagaa gaggacaaga tactgcaacc tggttacagt tacttaaaaa ggaaaaatat
    16261 gcatatggga ttcaagaaga tttagtgaat tacagattag ttggaaattc tatatcaagt
    16321 aacaagataa aagcattaaa acgaacttgg aatacttata gaaatgttga aaatttaagt
    16381 ttaccaaaaa gtctatatgt attttgtttc tatgttttta atgccattaa aaaaagagta
    16441 taagttttat atacttggag gtaaaaaaat gaaaatagct atagctggga cgggatatgt
    16501 aggtttggtt acaggtgttt gtctagcaga ggtaggcaat gaaaatgtag tctgtgttga
    16561 tgtagatgaa caaaaggtta aatcaatgaa acttggaata gcacctatat atgaagaagg
    16621 cctagaagaa cttatggtta aaaattacaa cagaggaaga atagattaca ctacagacta
    16681 taaaaaagct tatgaagatg tagatgtaat attaatagct gtaggtacac ctgagagaag
    16741 tgatggctca gccaacctag attatataaa ggcagttgca aagcaaatag ctgaaactgt
    16801 gacaaaagat actctagtag taataaaatc tacagttcca attggtacaa atgaagagat
    16861 agaagattat ataaatagaa acctaaaaaa tgatgtaaaa gtagaacttg catctaatcc
    16921 agagttttta tcacaaggaa cagcagtaaa agatactcta catgcttcaa gaatcgttat
    16981 aggtgtagaa agtgaatggg ctagagaaat attagaggaa atctataagc cttttaatca
    17041 acctataata gttacaaata gaaatagtgc tgagatgata aaatacgcat caaataactt
    17101 cttagctctt aaaatatcat ttatgaatga tattgcaaat ctttgtgaaa tagcaggagc
    17161 taacatagaa gatgtagctt taggaatgag ttatgatgat agaataggaa gtaagttttt
    17221 aaaggcggga ataggatatg gtggttcttg ctttccaaaa gacacaaaag ctcttcactg
    17281 gttatctgaa cataatggtt atgaattaaa aacagtaaaa gctgcaatag aagttaatga
    17341 aagtcaaaaa cttaaattag ttagaaaggc atctaagtta gtagagagct ttcaagatat
    17401 gaaggttgct gttttaggtt tgacttttaa gccagatact gatgatataa gagaagcacc
    17461 atctatacca aatataaaat atttgctcga aagaggggca agagttactg tatatgaccc
    17521 aattggtgta aataatacta agaaaatatt tggtgattct atactttatg ctgattctgt
    17581 agatgatgcg atagaagatg cagagatatg ttttataatg acagaatgga aagatgtatt
    17641 aaattatgat atacataagt ataaggaaaa gatgaaaaat cctttagtcc ttgatggaag
    17701 aaattgttat aaaattaaag atatggaaga gttaggaatt gagtattatt cgataggaag
    17761 gtaaatatta tgaagactgt ttgttattta gctgatgggt caaatcctca tactttaaaa
    17821 tggtgtagtt tttttaaaaa taaaggatat gacattcatg taatctcttt aaatggaggt
    17881 cacatggaag gaataaaaat ttataatttt ggttctaatg tagaagaact aaaaaatgaa
    17941 aatatttcta aaaaaacggg atacttaggt tcaataaagc agataaagaa gctagtaaat
    18001 gaaataaagc cagatatatt gcatgcacag tatgcaagta gttatggatt tataggcagt
    18061 ctacttgggt atcatccata tattatttct gtttggggta ctgatattta tgatttccct
    18121 aataatggtt ttatacaaaa acaaattata aaacataact ttagaaaagc agactatatc
    18181 ttttcaaata gtagagatat ggctaaagag gctaataaat atacagctaa acatgtagat
    18241 gtaacctttt ttggagtaga tatggatagg tttaagccta tggaagtaga aaaagaagac
    18301 gcttttgtaa taggaattat aaagagttta gaaaaaaaat atggaataga atatttaata
    18361 caagcattta agatgcttaa agatgaatat aaagataaga aaataattct taaaataggt
    18421 ggctctggaa gtcagatgga caacctaata aatttagcta aagaattggg tatagaaaat
    18481 gatgttcagt ttttaggaag aatatctcca gaaaatgtaa gcaagacttt taattctttt
    18541 gatgtaactg tatttccttc tttaagagag ggatttggag tggcagctat agaatcagaa
    18601 gcatgtgaag tacctgttat agttacaaat gtaggaggac atccagaatc tgtatgggaa
    18661 aatgaaactg gcttaattgt agaaccaaaa caaccagaag aaataaaaaa tgctataata
    18721 aaactaatgg aaaatgatga acttagactt aatatgggta agaaagggcg tcaatttgtt
    18781 agagaaaatt atgaggttaa tttaaacttt aatgatatag aaaaaattta tgattctata
    18841 tttgataaat ataaaaaata aaatgaaaaa atacagcaaa agatagatgt tgttggctat
    18901 gcttaggtgc gtagcttttg ctgtttaaag gagggcttct agttatgcga gaaagtatag
    18961 atttagagaa agaaagcttt tttaataggc tttttaaaaa atataaattt agacatttaa
    19021 cactattaat tctagatatt tgtagcgtac tagtagcgtt tcgaatgtct ttaagcttga
    19081 caggtaattt aaatgcattt accactaatg atataataat ttcagtgtgt atatatatag
    19141 tacttcatat agtatcattt agattgttta agtgctacaa cacattatgg agatatgcag
    19201 gagaagaaga aattatatct atttttgtgg caactttagc ttatttaatt ccgatttata
    19261 taataaataa attattaggg tttgattatc ctataatgtt ttatgtatta aatacaatat
    19321 ttattataat gtttacaagt ggcgcaagaa tagcctatag agctataaga atagtcatga
    19381 acaagacata ttctagagga aaggtttcaa atatccttat aattggtgca ggagatgcag
    19441 gagaaatggt tatacaggaa ctaaaaagaa atccagaact taaaaaagta gcagtggcta
    19501 taattgatga tgataaaaat aaaattggaa gaataatcca taatgtgaaa attgtaggaa
    19561 caacttcaga tataaaagat gtggtagaaa agtacaatgt agatgagata atcttttcaa
    19621 tagcaaacat agagaaacgt agaaaaaaag atattattga tatatgtaaa aacactaact
    19681 gtaaaataaa gacaatacca ggaatttacg aaattataga tggaaaagtt gatataaaac
    19741 agattagaga agtagagata gaagacttgt tgggtagaga gcctataaaa acaaatttaa
    19801 gagagataag taattacatt gagggaaaag taatcttaat aactggagga ggaggctcaa
    19861 ttggttcaga gctttgcaga cagattgcag gatttaatcc taaagagctt attatagttg
    19921 ataattatga aaataatgct tactcaatac aacaagaatt acttagaaaa tataaaaata
    19981 aattagattt aaaaacagta atagcatcaa taagagaaga aaaaagaatg gatgaaatat
    20041 ttaataaata taaaccagaa gtggtatttc atgcagcagc acataaacat gttcctctta
    20101 tggaatcgag ccctggcgaa gctataaaga ataatatatt tggaacttta aacatagctg
    20161 gcttgtcttc aaaatataga gctaagaaat ttgtccttat atctacagat aaggctgtaa
    20221 accctactaa cataatggga gctactaaaa gagctgctga aatgattata cagactatga
    20281 atgctgaaag ccagactgaa tttgttgctg ttagatttgg aaatgtgctt ggtagtaatg
    20341 gtagtgtaat tccacttttt aagaagcaaa ttgaagatgg cggaccagtg acagttactc
    20401 atccagatat tattagatat tttatgacaa taccagaagc agtaggctta gtcatacaag
    20461 ctggggctat ggctaaaggt ggagaaatat ttgtacttga tatgggagaa cctgtaagaa
    20521 tattggattt agcaaaaaac ttaattaaat tcagtggatt tgagccagat gttgatataa
    20581 aaattgaatt ttctggtctt agaccaggag aaaagttgta tgaagaacta cttatgtcag
    20641 aagaaggtct gttggataca gagcataaaa agatttttat tggtagacca atagatgttg
    20701 atagagaaaa aataacaaaa tacttaaaac ttttaagaga aattactaac aatgaagagg
    20761 ttgaaaaaat agatggtatt atgagggaat tagtgccaac ttatattaaa ccagaagatg
    20821 ctaatatcaa agaaattgca acaactagag aaaagtagaa tatatttcta atttgtaacc
    20881 agggggagca aaaagaaaca aatatatact aaaaagaaac aaaagattac aaaaagatta
    20941 caaaaagatt acaaaaaagg ttgcaattta ttttgatgta agatagaatg ttaattagga
    21001 attggaaacg aaggaacaaa atgttaaatt ttcgaaagga ttaggtattt gagattatga
    21061 tgaatattaa aaataaaaaa catatattga aaaaatttat agctatggtg ttaatagcag
    21121 gagttgtcac agtagaagca ggagcaataa cggctagtgc agcagagcca actaattcac
    21181 ctatgagtgc aacagtagac cagtgtgatt ttttaaatgt aagaagtgga gctagtgcaa
    21241 atgatgcagt agtaggaaag ataaacacag gagacaaagt tgaagtttta gaattacatt
    21301 caaatggatg gattaaaata aaaagtgttg acaatgttac aggatgggta aatggagatt
    21361 atttaactat tcaaggtgga aatgtagatg caaaggtaca aaatgtttta aacttagcat
    21421 ttaagcaaca aggtaagcca tataaatggg gagcaactgg accaaattct tttgattgtt
    21481 ctgggttcac ttcttatgtc tataaaaatg gagcaggagt taatttacca agagtatcaa
    21541 gatcacaagc aacagtagga aagaaagtat caagagcaga attaaaacca ggagatttag
    21601 ttttctttgg ttcaggtggt tcaataaatc acgttggatt gtatgtagga gattctaaat
    21661 tcatacattc accacaaaca ggagatgtag taaaagttac tagcatggct ccaggaacta
    21721 attatgcaaa aagacttata actgctacac gtgttttaca ataataatag atattgattt
    21781 acataggatt gaatattaac attaaatata taattacatt taatgtttta catagagatt
    21841 taagagttta gtaatattaa aatagtgatg aacgttataa aaacagcaaa gaagataaat
    21901 ttctttgctg ttttttttat aataaattat ttcatattat aatcaaatat caaatataaa
    21961 ttttaactat attattcaat atttgacaga taatatgaat tttagatata cttaataaga
    22021 agtatattgt agaaaaaata aatttaaaaa attaaggggg atgaaatgaa aaaaataagt
    22081 atattagtat tatcattgat aatgacactt actatgtgta gtgtaagttc atttgctgat
    22141 tcatcaaatg ataaggaaat gagagctgct tggatatcta cagtttataa tttagactgg
    22201 cctaagacta agaataatga agccaagcaa aaaaaggaat acacagattt attggacaaa
    22261 ttaaaaagtg taggaataaa tacagcagtg gttcaagtaa gaccaaaatc agatgcttta
    22321 tataaatcaa atataaaccc atggtctgaa tatcttaccg gtacacaagg taaagaccct
    22381 ggatatgacc cattaccatt tttaatagaa gaagcacata aaagaggaat ggaatttcat
    22441 gcatggttta atccatatag aataactatg gcagatgaga gcatagataa attgccagca
    22501 aatcatccag caaagaaaaa tccaagctgg gtagttaaac atggaaataa gtattactac
    22561 gacccaggtt taccagaagt tagaaagtac atagtggata gtatagcaga agtagttcaa
    22621 aattacgata tagatggagt tcattttgat gattacttct atccaggagt aagtttcaat
    22681 gatactgcaa cataccaaaa atatggaaaa ggacaaaata aggataattg gagaagagaa
    22741 aatgtaaata ctctacttag agatgtaaaa gcgtctataa agagtataaa gcctaatgtt
    22801 gtatttggtg taagcccagc aggtatatgg agaaataaga gtagtgaccc aacaggttca
    22861 gatacatcag gtaatgaaag ttatgtaggt acatatgcag atacaagagc atggataaaa
    22921 caaggattga ttgactatgt agttccacaa ctttactggc caattggtct taaagcagca
    22981 gattattcta aattagtggc atggtgggct aatgaagtaa aaggaacaaa tgtagactta
    23041 tacataggac aaggtatata taagcaaggt caatcgagtt atggtggaca aaatatagca
    23101 aaagaaatag tacaacaagt aacattaaat agaaagtata gtgaaataaa aggtagtatg
    23161 tatttctcag ctaaagatat agcaaatagt acttctatac aaaaggattt aaagagttta
    23221 tattctagta gtgaagaacc agttactcca ccatctaatg ttaaagtgga gaaattaaga
    23281 ggcgacgaaa gatatgacac agcagtagca ataagtaaaa aaggttgggc tacaaattca
    23341 gatacagtag tattagtaaa tgggtactct atagttgatg gtataacatc aacaccactt
    23401 gctacatcaa atgatgctcc tatactattg gtaaataagg ataatatacc tacatccact
    23461 aagaatgagt taaaaagact taatccaagt aaagttattt taattggagg aaataactct
    23521 attggagata aagttgagag tgagataaaa gatacattgt caaatgtatc aataaataga
    23581 gttggtggtt cagatagata tagtacatct ttaatgatag caaaagaatt agtaaaaact
    23641 aatccagtag aaaaactata tataacaagt ggtacaggtg aagcagattc tctttctata
    23701 gcttcaaaag caggagaaga aaagcaacca atagtattag tatcaaaaga taatgtaagt
    23761 gatgaagttt acaattggat atcagattta aaagtaaaag atgcttattt tataggtggt
    23821 aatctaagta tatctgattc agtaataaat aagctggata aggtcattac aaatgatgta
    23881 tctaaaaata gaatagctgg agaaaataga gaagaaacaa atggaaaagt aatacaaaaa
    23941 ttctatccaa atgctgaata ttcatcaatg tttgtaagta aaagtaatca attggtagat
    24001 gcattaacat caggtccttt agcagctaaa ttaaaatcac cagtagttat gcttggaaat
    24061 agtgtaacat ctgctcagaa aactgcttta gagcctaaga aaactactct agtatacgaa
    24121 gctggagatg gtataaatca aaacacatta aacactttct taaacttagt taagtaataa
    24181 aaaagttaat ttaaaataca gagtatttta taaatgtaga ttaaaatgaa aattatcatg
    24241 ataaattaga aaataaaaaa gaactatatg cattttgtaa tcaagtgtac acagcaactt
    24301 gaaaataatt atgcgatata gttctttttt agtaattaat cttatacttt ttaataaact
    24361 ttatgttgaa ttttttattg tttaaactct atgtcattaa atataaaatc gtgtaatatg
    24421 tctaaagtat ctgggtcaaa tctaagaacc catccagctt ttccatatat accacctgta
    24481 ctgtgaattt catcatcaat aggaaattca aattgcttaa tatttaagtc acccattttt
    24541 aaaacttgag ctcctaaaga aagtattgca ttaggcttca tgttagtttt aacatatgga
    24601 agaactgcat ctaataaacc tggatattta gtaacaggta aagtttccgt tttcttgatt
    24661 atagcttgta taatctgtct ctgtctgcca tctctagcaa aggctgtatc gttgtgtctg
    24721 atacgtgcaa aagatagtgc ctgatatcca tttagagtct gctttccaga gtttctaatg
    24781 tattgtatgc tacctttatc atcactttta ttccatttat aagtttcagg aataaattta
    24841 tttagttctc gtatttctcc tttttcaaca gtaacctcaa cgccaccaat agcatcaatt
    24901 atatacataa atgattcgaa attaacacaa gcataatttt gaatatcaat attaaaattc
    24961 tcttcaattg tttgtattaa taaatcagct tgtccataag cataagcatg agtaagtttt
    25021 tgtttaccat gaccagggat gtctacatag ctatcacgag ctaatgatgt aagtttgata
    25081 tcattgtgtt tgttatcaat agtaagtatc atcatagcat ctgaccttga agaatcttca
    25141 tttggtctag catctgttcc cataagtagt atgttaatta tcccatcttc atttttatgg
    25201 tcattgttat ccaataaatc actacttatg ctcgagtcat gaatagcaga taatttataa
    25261 taaaaatatc catagacact tatagggaat attactacca agaaagccag tagtataaca
    25321 aatttcttta attttgacaa aagtacccct tctttcttct ttttcctgta tattttttaa
    25381 tagcatacac ttaattatat taaagtattg agatatattc aatacttgtt tcagttacaa
    25441 aaaaaagaca atgatataat ttataagaaa atttatcgac ctatatatat agttaaaagt
    25501 atatataata tattttttaa aagtaattta tattttaaaa taaaaacaca ccccataaat
    25561 acaaaataat ttgcatttaa gaggtatgta tttatcatca aattattggt ttgttttgga
    25621 atttctaatc ttcaaccata atatctttaa atatgaaatc atgcattgca tctagttcat
    25681 attcctcaaa aggtattaca tagcctgcat tacctatttt tctaccattt tcagtagaaa
    25741 gaggaaactc catagatttc aaatttaaat ttcctatact taaaagttct tttcctaaag
    25801 atattatttc attaggattc atattagttt ttacatacgg aagtattgtg ttaactagat
    25861 taggatattt agtgactggt aaatccttaa caccatttat taaactctgt ataacacttc
    25921 tttgtcttct atctctttca tctgtgctat cattttttct tatacgagaa aatgcaagtg
    25981 tctgatatcc atttaatttt tgctcaccag aatttcttat atatttaaga gaacctttat
    26041 tgtcattttt attccattta taagtttcag gaataaattt atttaattct cttatttcac
    26101 tcttatcaac agtaacagta actccaccta aagcatcaac tatatccata aaagagaaaa
    26161 agtcaactac ggcgtagttt tgtatatcaa gttggaagtt ttcttctata gtttctatta
    26221 ataagttagc ttgtccatat acgtaggcat gtgttaattt ttgttctcca cgtcctggta
    26281 tattaacata agtatctcta tttaatgaag ttagcttaag acttttattt ttattatcaa
    26341 tagtaagtat catcatggca tcagaacgag aaacttcttc tcctggtctt gcatctgtac
    26401 ctaacaataa tatgtttgtg atattttctt cgtttttata gtcattacta ctaagcgcct
    26461 ctgtatttat actatcatct tgtatagttt ttaatttagt aaaaacatat ccatatatac
    26521 taacaggaaa tgctataact aaaagggcta gaaatataac gaactttttg agtcctgaca
    26581 ataatatccc ctactttcta aattttttaa ttacacatag ttaattatat taaaaatttg
    26641 ttacataagc aataaaaaac acaataaatt agcataagtt tgtcataata taattatttt
    26701 tatagtattt tatagaagaa agtgtgtagt tattattgat tttattggaa tataattgta
    26761 tgaagactta aatttttata aactaatgtg tatattgaaa aaaatatttt cctgaatgta
    26821 gttatagcat cttatgaaag gtgcaaattg taatttaaaa tttttagtgt ataataagaa
    26881 ttgaaaattc aaaccgataa aaattaataa aaaataatta taaattaata atttggggga
    26941 ggaaatgtat gataaaatta atagcaacag atttagatgg aactttgtta gatgaaaaga
    27001 gcgaaataaa tccagagttt tataaagtat ttaaaaaatt aagagagaga gggataatgt
    27061 tttctgctgc tagtggcagg cagtatcaaa atcttataaa aaaatttgaa gatataaaag
    27121 atgatatgat gtttatatca gaaaatggaa cactagtagt atataaagga aaagaaatat
    27181 tatcaaatcc tttaaataaa gaattagtaa atgaaatcat agagacaaca agaagtataa
    27241 aagggaaaaa aattgtaatg agtgggaaaa aatacgctta tatagaaagc aaagatgaag
    27301 cgtttataca agaggtcagt acttattatg caaagtttaa aattgtagaa gatttgacga
    27361 aagtagaggg agacatattg aagatagctg tatttgactt caaaggtgca gaacataata
    27421 ataatatcta ctttgaaaag ttttctgata gagctcaagt atgtatttct ggagtggagt
    27481 ggcttgattt aactgcaaaa ggtgcaaata aagggagtgc cataaaaaaa gtacaaaaaa
    27541 tgttagatat aaaatatgaa gaaactatgg tatttggtga ccagttaaat gatgtggaaa
    27601 tgatgaaaag tgcctatcat agttatgcca tggaaaatgc aaatgaacat ttgaaacaaa
    27661 ttgctagatt tagagcaaaa agaaatactg aaaatggcgt tgtagataag ataaaagagg
    27721 ttataaaaat tggatagtca tatgtataga tgaaaaagat tattttgaag aaatcaaaaa
    27781 aatatcaatg taattttgat aaataagttt atttatgcga aaattacatt gatatttaat
    27841 aaacatcaat aatagatatt tattttttta tgatattcag tattttgttt tctatttgag
    27901 ttgcattttc agcagaaatt aaataaacat atctacctgc cttctcaatt atagtattat
    27961 ttgctatttc agaattgatt ttttctccat gtccttctcc aaaaggtgct tgtatcatat
    28021 cttttttata attttctaga gttttataga ttttatctac ctcgtcagtt tttataacga
    28081 taatatcttc tagagataat ttttcagaag aattaattac aaaaccttga attatgtctt
    28141 cctctacatc attaaaatag ttaaaatcct ttgcatcaaa gatttttgat tcctttataa
    28201 gtaaatcaga agattttaat gcttttttta tttttgatgt agaaacgttt ttgtaatcac
    28261 cacttgaaga acaactaacc attcctaatg ataagattat cgaaaaaaac aatattaaaa
    28321 tttttttcat gataaacctc caagtttttt aaactctgtc ttaaattagt ttactacata
    28381 attatataaa aataaatgta tttaatgtta cagttttgat taataatgta atattttgat
    28441 aataatacct attgagaggt gattagaaat gagaatacca aaacatgtag gaattatacc
    28501 ggatggaaat agaaggtggg caagtcaaaa tggtatgaca aaagataaag gatatgaaag
    28561 tggaatagac cctggactag agtcttatag attatgtaga gatttaggct gtgaagaggt
    28621 gactttttat ggatttacaa ctgataatac aagacgtcca tcagtgcaga caaaagcttt
    28681 tacaaaagca tgtattgatg ctgcaaatat attaatagat gaaggtgctg ctttattagt
    28741 tgtaggaaat acaaaatcgc caatgtttcc agaagaatta ttaccatata ctaatagaat
    28801 taaagccaaa gaaggtcaaa taaaagcaaa tcttctggta aattatggtt ggtattggga
    28861 cttaaataat atatcaggag tagaaaatgt aaataaaaat aatatacagg attacataca
    28921 gtcatttgat gtatccagac tagacttgat aatcagatgg ggtggaagaa ggagattaag
    28981 tggtttcctt cctgtacaat caatttatgc agatttttat gttatagata attattggcc
    29041 agattttaag agtgacgata taaaggacgc atttagttgg tatgatacac aagatgtaac
    29101 tttaggtgga taattaaaaa tattctgatt taaggttgta gagtgtttta aattattgaa
    29161 aaaaaaactt cttgatggta aaataacact aataatatgt aaaagtgtaa aaatttatac
    29221 caagaagggt gaagaaatgt caaaaggcaa taataacaat aattcaagaa acaaatctaa
    29281 aaagaccagt catctgaata gaaaaaagcg aaaattaaat aagaaaaagt tagcagtgtt
    29341 gatttgcttt acagttttat ttttatttat tgcatttaag gctactcaag gtgtagtagc
    29401 tttggtaaaa agtatggata aaagtaataa aactaatcaa caacaaaatg ttaactcaga
    29461 acaatttgac cttggtaatg aagaggaaaa taaaaagaaa aaatatactg tatttataga
    29521 cccaggtcat ggaggcaatg ataaaggaac tgaaagcaag accagtaata gatatgaaaa
    29581 agacctaaat ctacaaattg caaaaaaatt agcaaataaa ttatctaaac aaaaggatat
    29641 tcaagtagta gtatccagaa ctgatgatac atatatatca ttaaaggata gagctatctt
    29701 agcaaataat agttctgctg atgtgcttgt ttctattcat ttaaatgcag agaaaaatgg
    29761 taatacagca acaggtatag aaacttggta taggaataaa gctacagatg gttcaaaaga
    29821 acttgcacag acagtacaaa gtactatagt atcctatgtt aaagttagag ataggggaat
    29881 agttgaaaat aactttgaag tacttagaga atcaaatatg cctgctatat taatagagtg
    29941 tggtttttta acaacacctt cagaggaaca aaaaataata aatgaaaaat atcaagacca
    30001 acttgcggaa ggaattgttc aaggtgtact ttcataccta gattctaaag ggaataagta
    30061 agttaacttt actttaatgt gaggataaat ttaaaagttt aactgtgtaa attgtattaa
    30121 ctttatttcg taatgttgga aatattgttt gaatttagaa actatgaaat tagaaattat
    30181 tttatctata tctaatttca tagttttttt tgcaaaaaat ttatagttat aaaattttaa
    30241 aaaataaatt tagtataatg taatgtagtt atttatatgt gattttaact tgcattgatt
    30301 tgctatcaat tgtgctttat aattagtata tataaagttt aactgtaaga taatttaaaa
    30361 aataggggaa tttatatgaa taaaaatagc atgacaagaa tttacagttt aaataaaata
    30421 atttttatta taattggaat tttaggaata gttttactca caagacatat tgaggtagat
    30481 attaaagttt taattttaat tttattaacc ttgtttagta taaatgtatt tatttcatat
    30541 cttaaaatta agttgtatga ggataaaatt aatttaggat tgataaataa ttcagataag
    30601 tttataaata ttactaaaga tgagaacttc ctaaaacatg ttcaaaatta tattatcagt
    30661 aatgaaaaag aaaactgtgt aatggcttgt tttgatttat gtagactcaa acttataaat
    30721 gatatatatg gttatgagct aggggatgaa gtgttaaata atattttaag taacttaaaa
    30781 aattattttg gaaaagaagc tatttatgga aagttaaaaa gtgatgtttt tgtattaata
    30841 ataaagcttg aaaataggga acagaagatt ccttatttag taaatcttat taagaataaa
    30901 attgtgatac taagtcagat tgacagtttt aaaatggata taaatattga ggcttctatt
    30961 ggaatttata aatttaacaa taatgaaatt gatataaaaa aagctataga taatgctgat
    31021 atggcaaggc ttaaatcaaa aggactaaag cacatagagt atgtagaatt tgataatgct
    31081 atggaagaag aaatacaatc aattatgaaa atagagagag atttattctt ggctattaaa
    31141 aataaagagt ttgtaattca ctatcaacct aaagttgatt caagtacagg taacattata
    31201 ggttcagagg cattgataag atggttgcac ccatcattag gcatggttgg accaaataag
    31261 tttataccta tagctgaaaa aaatggtctg ataaacaata ttggtagatg gctaattcaa
    31321 gaagttttta ttaccattaa caagtggatt tcagaaggta taaatgtctt accagtctca
    31381 ataaatcttt ctagagtaga actatataaa aatgatttag ttgatttttt taaactgatg
    31441 tttaatacat ataatattcc aaaagaactt atagaattag aaattacaga aacgacagca
    31501 ctaagagatg taaaatttat aagtgaaagg ctttatgaga ttaaatcttt aggtatgaat
    31561 atatcattag atgattttgg agtaggtaat tcaaatttta tcaatcttaa ggggatacca
    31621 ctagatatta taaaaattga taggtcactt atattggata tagttacaaa tacaaaaaca
    31681 aagtttatgg tgaaagcaat tgttaacctt tcacatgatt taaacgtaac tgttatatgt
    31741 gaaggggtag aggatatgca tcaggtcaaa gtcttaagtg aactgggatg taatttcata
    31801 caaggttatg tattttttaa acctttggat gagatgaatt ataaaaaact tcttactgac
    31861 ggaagttata taaatctgaa agatactctt ttagataaat gcatgacagt tgaggaggag
    31921 taaggatgat ttcagaagat gtagattatt caataagaat cataagagct atatttaata
    31981 atggagaaga taaaccaata gatgctaaaa tgatattaaa aagtgaagat ataccaatac
    32041 taacactata cagactgctt agaaagcttt gtgcaaacaa tattcttact tttaacaaag
    32101 aagatggcaa gacatacatg ttaaatgtgt cattggatac aataagtcta agaactattg
    32161 tagaagtaat tgatggaaaa atatatataa ataaatgtac gagatatgta tctaattgca
    32221 gtaattgctt aaaaggttgt aaagtaaatc gtgaattgct agaaatagaa aaagaaattt
    32281 ataaactttt atcgagaaaa tctataagac aaatactaga ataaaaaatt ttcagctatg
    32341 ataataattg gaggttttcg gttatggatg atatatctca agataatttt ctactgtcta
    32401 aagagtatga gaatagctta gatgtagata ctaaaaaagc aagtggaata tattatactc
    32461 ctaaaataat tgtagattat attgtaaaaa aaactttaaa aaatcacgat ataattaaaa
    32521 atccatatcc acgaatactt gatatttcct gtgggtgtgg aaattttctt ttagaagtat
    32581 atgatatttt atatgactta tttgaggaaa atatatatga attgaaaaag aagtatgatg
    32641 aaaattattg gactgttgat aacatacacc gtcatatatt aaactattgt atatatggtg
    32701 ctgatattga tgaaaaagct ataagtatat taaaagatag cttaacaaat aaaaaggtag
    32761 taaatgattt agatgaatct gatataaaga ttaatctatt ttgttgtgat agtcttaaaa
    32821 agaaatggcg atataagttt gattacatag tgggtaatcc accctatatt ggtcataaaa
    32881 aacttgaaaa gaaatataaa aaatttctcc tagaaaaata tagtgaagtt tataaggata
    32941 aagctgactt atatttttgt ttttataaaa agattataga tattttaaag caaggaggga
    33001 ttggcagtgt tataactcca agatattttt tagaaagtct atcaggtaaa gatttaagag
    33061 aatatattaa atcaaatgtc aatgttcaag aaatagtgga ttttttaggt gcaaatatat
    33121 ttaaaaatat aggggtatct agttgtattc taacttttga taagaaaaaa acaaaagaga
    33181 catatataga tgtatttaaa atcaaaaatg aggatatatg tataaataaa tttgaaacat
    33241 tggaagaact tctaaagagt agcaaatttg aacattttaa tataactcag agattgctat
    33301 ctgacgaatg gatacttgta aataaagatg atgaaacttt ttataataag atacaagaaa
    33361 aatgtaaata tagcttggaa gatatagcaa taagttttca aggaataatt acagggtgtg
    33421 ataaagcgtt tattttaagt aaagatgatg taaagttgaa ccttgtagat gataaatttt
    33481 taaaatgttg gataaaaagt aagaatataa ataaatatat agtagataaa agtgaatata
    33541 ggctaatata ctcaaatgat atagataatg agaatacaaa taaaaggata ctagatgaaa
    33601 ttatagggct atataaaaca aaattagaaa acagaagaga atgtaaaagt ggaataagga
    33661 aatggtatga acttcaatgg ggtagagaaa agcttttctt tgaaagaaaa aagataatgt
    33721 atccttataa atcaaatgaa aatagatttg ctatagatta tgataacaat ttttcaagtg
    33781 cagatgtata ttcttttttt ataaaagaag agtatttaga taaattttca tatgaatatc
    33841 tagttggaat tttaaattcc agtgtttatg ataaatactt taaaataact gctaaaaaaa
    33901 tgagtaaaaa tatatatgat tactatccta ataaggttat gaagataagg atttttagag
    33961 ataataatta tgaagagata gagaatttat caaagcaaat aatatcaatt ttattaaata
    34021 agtctataga taaaggaaaa gtagaaaaat tgcagataaa aatggataac ttgataatgg
    34081 attctttagg tatataagca gttgtaagta ttaaaaaatt ataatctttt aattgtttat
    34141 ttaaatttag aaataaaaag ttagccatat aaaaaatatt aaaaatatat acttttcaat
    34201 atttttttga taaaataaga atgaatttgt gcaattttat ttttctccaa taactaaaaa
    34261 tagttttttg aattaatatt tgcttaagaa taaaaatcag aaacgttttt gatatagtag
    34321 gtgataatat gaaaggatta gttttagaag gtggaggaac aaaaggagcc taccaaatag
    34381 gtgcatataa agctttaaga gagcttggta tagagtttca aggagtaact ggcacatcaa
    34441 ttggtgcttt aaatggagca tatataattc aaaatgatat tgaagtaatg gaagatattt
    34501 ggttaaatta tgactatact cattttatga atattgatag agaaacctat gagaggttta
    34561 aaaatgtaga tttcactact aaaaatctca atgcagtgtt tgagcttata aataaagcta
    34621 gaaaaaatga aggtatagat ataagcccat taagacaact aatggagaca acattaaatg
    34681 aagacataat aaggaaatca aaaaaagact ttggacttgt tacggtctgg tgggataaaa
    34741 aaattaatcc atatccattg tatatcgaag atatacctaa aggaagattg attgattatt
    34801 taattgctag ttccagtttg cctatttttc aaacgaacat gatggatgat aagttgtatc
    34861 ttgatggaat gttttgtgat aacatgccaa taggactctt ggaagacaaa ggttatgaag
    34921 atgttgttgt aattaggttg attgatgatt ttattgggaa aatgaatcta aatcgacatc
    34981 aaaatataaa tataaaaact ataataccat cagaatatct aggaggttct cttaataaag
    35041 atagagataa tgtagaaaaa aacatccgac taggttactt agatactatg aaagcatatg
    35101 aaagatgcac tggaattaag tattattttg atgtagagta taaatataat gaagaatatt
    35161 gttttgataa atttagaagt atgagcaatg aaacaataca atatatctgt aatttattga
    35221 atataaaaag agatgcttca cttagaactg ttatggaaag tgtaatacca aagcttggtg
    35281 aggtgcttgg attgccaaag gatttttcat ataaagattt gttttactgt atatatgaaa
    35341 agaaacttga agaaaataat ataaacagga taaaattata tgattttaac aaggttatag
    35401 atgttgtaaa tacaaatatt gattctaata gaaatttagc ttctaatttt gaagttagac
    35461 ctaaaattag tattaaaaag aacaaaaaca caaaattatt gacaaattgt attataaaag
    35521 acataaaaaa tcaaagttaa ataaaaaaca aaaaaaaatt tgtaattata ctcgaaaaaa
    35581 gtgtatatta gtagtataat atttttgtag cactagtggg aacaaaaaat gaccatagga
    35641 caaaaaagta ccacttagta ccattaaagt aaaaaacagg aaaacaattt taaaaaatat
    35701 aaaatgtaaa gtttatagga ggatttaaaa aaatggaaaa agtagttagt atcaaaaatg
    35761 caagtggatt acatgctaga ccagcaggaa tgtttgttaa gaaggcagct gaatttaaat
    35821 caacagtaga ggttgtagca aaagacaaaa ctgtaaatgc aaaatcaata atgggaataa
    35881 tgagtttagg tttagctcaa ggagaagaat taaagttagt tgtaaatgga gaagatgaag
    35941 aagtagcttt agctgcaatg gttgaattag ttgaaagtgg atttggagaa tagatataat
    36001 aattttttaa aaatttgata tttagaatct aatattactt aaagtaaagt aacagagaag
    36061 tattaaacat atacagacca acatttgtag atatttaatt tctttgttac tttcatgttt
    36121 atttaatcag aagattaaga ctattgttaa ttgggtataa aaatataaat attttagaaa
    36181 atgaaataag atatttttaa tcataaattc agagtaaaaa tacagtaaca aatagtttat
    36241 aaaattttat aaaaaattat aagtaaataa aactataaaa atgtaaatta tttataaaat
    36301 tttatagagt ttatgtgcta gatgatattt tttaggaggt agggttatgg cttacaaagg
    36361 aataggtgct tctcctggtg ttgctttagg gaaagcgtta gtagttgaac atagtgaatt
    36421 agtaattgaa aaaaaatcta tagataatgt tgaagctgaa attgctaaat tagaaaatgc
    36481 agttgcagtt tctaaagaag aattagtaaa agttaaggaa aaggcttctg aagaattagg
    36541 agcagaggaa gcagaaatat ttgaagcaca tttattagtc ttagaagacc cagaattaat
    36601 tggttctgca atagataaaa tcaaaactga aagtgtaaat gcagagtatg ctttaaatga
    36661 aataaaagag atgtttgtta gcatgtttga gtctatggac aatgagtaca tgaaagaaag
    36721 agcggcagat ataaaagatg ttacaaatag aatacttaga catatattag gaattaaagt
    36781 tgttgattta tctgctttaa gcgaagaagt tgtattaata gcacatgatt taactccatc
    36841 agacacagca actatgaata aaaaaatggt tttaggattt ttaactgata taggtggaag
    36901 aacttctcat actgctatca tgtctagaac tttagaaata gctgcaatcg ttggattaaa
    36961 tgatataact tcaaaagtta aggatggaga ttttgtagtt ttcaatggag acacaggtga
    37021 agtaatcgtg aatcctgatg aagagactat aaataaatat actgaattaa aagctaagta
    37081 tgaagatgag agaaaagcat tacagctatt aaaaggaaaa ccatctgtaa ctttagatgg
    37141 aaaacatgta gaattagctg gtaacatagg aacacctaac gatatagaag gtctaataaa
    37201 gaatgatgct gaaggtgttg gtctttatag aacagaattt ttatacatgg atagagattc
    37261 tttcccaaca gaagaaatac aatatgaagc atacaaagct gtattagaag gaatggatgg
    37321 aaagcctata gttataagaa cattggatat aggtggagat aaagaattaa gttatttaag
    37381 tatggaacct gaaatgaatc cattcttagg ttacagagca ataagacttt gcctagatag
    37441 aaaagatata tttaagactc aattgagagc tttatataga gctagtgttc atggaagatt
    37501 aagaatcatg ttcccaatga tttcatcttt agaagagttg ttacaagcta aagaagttgt
    37561 aaaagaagtt ttagcagaac ttgattctga aggtgtggct tatgctaaag atgtagaaat
    37621 tggtatgatg atagaagttc catctgctgc tgtgatatct gatgtattgg ctaaacacgt
    37681 agatttcttc tctataggaa ctaatgattt aattcaatac acttgtgcag ttgatagaat
    37741 gaatcaaaag ataagttatc tttacaatca atttaatcca gctgttttaa gacttataaa
    37801 gactgttata gacaatgcac acaaagaagg aaaatgggca ggtatgtgtg gagaatctgc
    37861 tggagaccaa aaaatgatac caatactttt aggtatggga ttagacgagt tctctatgtc
    37921 tccaatatca atacttcctg ctagaaagtt aataacttca gttaaagagt cagatatgaa
    37981 aaaattagct gatgatgtac ttaatatggg tactgctgaa gaaataaaaa gctatataga
    38041 aaagactttt aatatataat taatgttata tagttactaa aattcatttt tctaaataac
    38101 aaaattatat tttacgaatt aaaaagaaga tgtttcaaaa taaaaatttg aagcatctct
    38161 tttttataaa agattactaa gaattactta atctttgtaa tagtcatttt gtgaaaaagc
    38221 aaaactgcat tgtgactata gtatatatgg atgttattat caataaaagt actattaaaa
    38281 tgaagattca ttctcaaatg gtatcaaaag tagttgtgat ggagtaagat aatattttgt
    38341 gatttaatag taaaaattaa aaaaatatgg tattgaaaaa taattaaaag tatttaataa
    38401 tagaattagg gaagaataag tttataagta aaaataattg attagtagtt aataaaataa
    38461 atgtgatatc caaataaatc ctaaatctaa tttgagtttt aatatagata gtctaaagtt
    38521 tgattattaa agatttaatt gtaagttgtt acagttgatg atattgatta gagattaaag
    38581 tttagagtag aaagttacct taaatttaaa aatgcaagat aacccaatct aaaaattata
    38641 atcactcgat aggtttaagg atttatttgt ttattataaa taggagggtg tctcaaaatg
    38701 aactttttag tttatgaggc actctctttt atatagaatt aaatatattt tattatttca
    38761 acaatgaaaa agaagcttat ctctattttg agacagcctc tttgtatact attattaatt
    38821 taatcaataa cataatttaa aattatatta ttagttaaga tttcctgctt tattagtaaa
    38881 taattcttta atagcattgt ttctggaaac taaatcgtta tcagagttgt ttgttttttt
    38941 cataatcact gaataacgtt ttttatttat aaaaaatatt aaaatcttat catcatcaaa
    39001 attgtattct ttatatctgt caatagactc ataacctaga tttagaatgt ttttgtcttt
    39061 tatactatct acatctaaaa tatatgatgg gtcagccttt agtaatatat taattaaaca
    39121 tttttcttca ccagcacaga ataactccat cttacttgat atagatttag attgctctga
    39181 agttattttt gcaggaataa ggttgtcatt atcatctctt agaagataac catgtgtgtc
    39241 ttgttgatat actaaattaa cctttttctt aggaacacta atcattttat ctaaatgtac
    39301 ataatgatga ttttcaacaa aaccttcatt taatatttca acaaagttat taattttacc
    39361 taggcaaaaa gattctatag attctttaca gaatttattt gtaaatggta ttatgtttac
    39421 gttttcctcg tctgtattcc atgctatagc ataatccaac gaatatactt cttcctctat
    39481 atctgcaaaa ttatattgta ctatgtttcc tttcaaaatt actcgacctc catcttataa
    39541 tatatttaat atactttata aaacttatat tatatttaaa taatatcata aattggataa
    39601 atatgatata gtaaataaga aaaaatttga aaaaaatcac tataaatgag taataaatat
    39661 aaatagtgta tactaatggg atggaaaatg tccactatta actttattac cccacatata
    39721 taagataaaa ttattaatat aaaatataat ctatcgacaa tgaatagact tttaaataaa
    39781 cttaatataa aattaattaa ataagtgctt aaaaacgatt tactttaatg atagaatcat
    39841 attaaaggag gataatttta tggatataaa gaataaaatt aaatctatat ttttaccaga
    39901 aaaaaatgac tatttagatg atgaagaatt tgagtatgat atagaaaata atgaagaaga
    39961 tttaaaggaa gataacaaag tacatttaaa tgatttaagc agagtaaaat atgattacag
    40021 agagttaaaa gacatagaaa accaaacaga agagatgtgt ctgctagcag taaagcagga
    40081 tggtactata attgagtttg taaaggacaa gacttataaa gtatgtatgg aagcagtaaa
    40141 acagacatat aaatctctta agtatataac aaatcaaaat gaggatattt gtatagaagc
    40201 agtaaaacag aactacagag ctttgtacta cataaataat aagacagaaa atgtactaat
    40261 tgaggctata aaaaatgcat caacttatga tgtcatggaa gtatttaaat ttgtggaaga
    40321 gcaaacagaa gatgtatgtc tagcatttat agaaagggca tctaaaaatg atgttgcaga
    40381 gatattaaaa ggaataaaag agcaaactcc agccatatgt ttagaagctg taaaaaaaga
    40441 tggaaaatct ttagcttatg taaaggaaca aagtaatagt atatgtttag aagctgtaaa
    40501 agaaaactac agtgcactat cttgtgtaaa agagcaaact gaagaaatat gcatagaagc
    40561 agtaaaacag aatgactttg cattgtatta tgtaaatgaa cagacagaaa aaatatgtat
    40621 ggaagcagta aaaagaagtt atatggctct acagtatgta aataagcaaa cagaagagat
    40681 ttgtttggaa gcagtaagaa ttgatggaag agcattacag tacgtaaaag agcaaacaga
    40741 agaaatttgc ttggagtcag ttagacaaaa tggaaaagta ctgcaatatg taaaaaaaca
    40801 gactgaaaat atatgtatag aagcagtaag aggttcattt gaagaacttg aaataaaaga
    40861 aatattaagt tatgtaaaga taccaacaga aagaatattt gtagaagcag taaagcaaaa
    40921 tggaaaaatt cttaaatatg tagaaaatca gacagaatta atatgtttag aggcagtaag
    40981 agaaaactat aatgctttag cttatgtaaa ggaacaaaca gaaaagattt gtttagaagc
    41041 agttaatcaa agttatgaag cgcttaaata tgtgaaagaa caaacagaag aagtttgtct
    41101 aaaagcagta aaacaagatt atagaatgtt gaaatatgta aataatcaaa cagaaaaaat
    41161 atgtttagaa gcagtaaagc aaaattatag agctttagaa tttgttgata atcaaacaga
    41221 aaaagtttgt cttgaagcag taaaacagaa tagaaaagca ctacagtatg taaaacaaaa
    41281 acaaagttaa aaggctaaaa tatatagaaa atatatgcaa ataaataaaa tttgatattt
    41341 tgtaataaat aaaatgggta tctcaaaatg aactttttag tttgtgagat actcttttta
    41401 tatgaaataa aatatatttt tagcctttta acaataggga aaaggtttat ttctattttg
    41461 acataggctt tttatgcata taaagcttga taaaattgtt ttattataat tgttttgtta
    41521 tatgaataat aagaagaaaa ttatataggt ctttttttga ccagttttac atttttaaca
    41581 actagttttg taaagtatat tgaattttct caaaaaagaa tgtactctat atatgtaaaa
    41641 tttttttgga ggtaaaaatg tttaaaagat atgctgaaaa aatgacatct gttttaattt
    41701 gtaataatat gatagataat aatgaatcta aagtctattc ttatggattt gaaatattaa
    41761 tagctttcat agttaatata accaccatgc tgtttatagg ttttttattt ggtaaattta
    41821 catatgtatt atttttttta atgtgttatt gtccaataag acaattttca ggagggtatc
    41881 atgcagacaa ttattttaga tgcttattaa cctttatttt tataatttta tctacaatct
    41941 taattataga aaatataaat atagacttat ttaaaaatat tattatgatt attgcaagtg
    42001 ttagttgggt tggaatttgt gttctgtgcc caatagaaca taggagtaac cctataagtg
    42061 atagggaaaa gttggtttat aagaaaactg ctatatttat atctacagta gtgttattga
    42121 taacaatttt aagtctttct ttgagtatat ttgtagatta tttcacatat agcgcatttg
    42181 ccatgttttg gatttttgtg atgttagtat taggtaagtt aaaagctaaa gtataagtaa
    42241 aatatgtatg agggagagtt aagttatgaa aaagtttatt gtaagattta tgaagtttgc
    42301 tagctcattg gcacttagca ctgctatttt gtcagctaat agtacctgtc cttggattat
    42361 tcatcagcct aaagtaccca aagaaatcag caatctaaag aagacaaatt aaatacaagc
    42421 acttatttat acaaaattat caggaaaaaa gaaattatta tattttaata agattaaaac
    42481 aatataaaat cagatacaaa atttatttta tttattttat aggagcctaa tacctatttg
    42541 gtaatatatt agtgcgccaa tttaggggga tatagtgtat ttaatgaaat gacttacgga
    42601 gagtaagtca tttttgtatt gtatgtattt tatgtaaact tatgatataa tgaagggtaa
    42661 agtttaatta aaataataaa aaactttagt atagatagta atttaggagg tagggtatga
    42721 gtatgataca taaattttct atgaatggat ataatatcgt tttagatgtg aatggtggag
    42781 ctgttcatgt gttagatgat gttgcatacg atttgttaga tttttataaa gaaaaaagta
    42841 aagaagaaat attagagata ttaaaatcaa aatatcaaga agaaaaaata aatgaagcat
    42901 atgaagaaat attaaatttg gaaaaagagg gtcttttata tacagaagat acatatcaat
    42961 atcatccaag ctttgtacat agagagcctg tagtaaaagc tttatgttta aatgtagctc
    43021 atgattgtaa cttaaaatgt aaatactgtt ttgcagctca aggtgatttt ggaggagaaa
    43081 aagaacttat gagttttgaa gttggtaagg cagcaattga ctatttgatt gctaattcag
    43141 gaagtagaaa gaacctagag atagatttct ttggtggaga gcctttgatg aactttgaag
    43201 ttgtaaaaca actggttgac tatggaagaa gtgtagaaaa agattataat aaaaatataa
    43261 gatttacaat aactacaaat ggtgtactgc taaatgatga gattatagat tatataaatg
    43321 aaaatatgca taatgtagtt ttaagtttag atggaagaaa agaagttaat gataatatga
    43381 gaccaacttt aaatgataaa ggaagttatg atattacatt accacgattt aagaaacttg
    43441 tggaaaaaag agcaaaagat aagtattatt atataagagg tacttttaca agagataatt
    43501 tagatttttc aaaagatgtt atgcattttg cagatttagg atttaaatta acctctgtag
    43561 agccagtcgt tggagatgag agtaatccat atgcacttag agaagaagat ttacctaaga
    43621 tatttgaaga gtacgaaaaa tttgctgtag agtatgcaga tagacaatta caaggagatg
    43681 gatttaaatt tttccatttt atgatagacc taaatcaagg tccatgtgta ataaagagaa
    43741 taactggatg tggagctgga aatgagtatc tttctgtaac tccaaatgga gatatctatc
    43801 catgtcatca atttgttgga aatgaagaat ttaaaatggc aaatatattt gatgaagaaa
    43861 tagtacttcc agaaaattta aaaaatatgt ttagagaagc tcatgtatat actaaagaag
    43921 agtgtaaaca atgttggaat aagttttact gttcaggtgg atgtcatgca aatgcgataa
    43981 actttaataa tgacatatca aaaccatatg aattaggatg tgaaatgcaa agaaaacgta
    44041 cagagtgctc tataatgata caagctaagt taatgttaga aggagcaacc aactaaattt
    44101 atattttaaa ggagttgttt atatatgatt agagattatt tagaagataa acctttaatt
    44161 gacgaaagtg tatttgtggc aaaatcagca gatgtaattg gaaatgttaa aataggcaaa
    44221 gattcaagta tatggtacaa tgcagtagtt aggggtgatg aaggaccaat aactattgga
    44281 gaaaacacta atatacaaga ttgttctata gtgcatggag atacagaaac tataattggt
    44341 aacaatgtaa cagttgggca taggtctata gttcatggtt gtaaaattag tgataatgtg
    44401 ttaattggta tgggttcaat aatattggat aatgctgaaa taggagaata tactctgata
    44461 ggagcaggta cactaattac atctaataag aagtttccac caggtgtttt gataatgggt
    44521 tctcctggta aggttgttag agagcttaca gaagaagata aaaaatatat tgatgaatct
    44581 tatgaatggt atttagaggc agcacaaaat caaaaatatt agtttaaaga gtggttgttt
    44641 caaaacatat ttaaatctgt tttgaggcaa ccactaattt attttattag attttgttga
    44701 tattttagtt ttcaaaaagt atttgattaa accagatata aaatgtcaaa aataaaaatt
    44761 aactgagtta aataatttta ataaaattgg tagtatatgt gataaaatta aatattaaag
    44821 aggatatagg atattagaat atcaattggt gaaataatgt catatacgat aaattaaggt
    44881 gtaagttttt gggtatacct atcttaggag tgaaaagatt tgagaataag ttatagaaat
    44941 ttaaagcgat atagagaaat tggatatgtt ttaataaagt atggttttag ttttattgta
    45001 gaaagactaa atatagaagg aattgcctat aaaataccac tatttgaccc accagaagaa
    45061 ataaaaaata tgacaactgg tgagagaatg aaaagagttt tagaagaact aggacctaca
    45121 tatataaaaa taggacagat attgagtaca agaaaagact tgttagacca ggatataatt
    45181 gatgaaatat caaaactcag agatgatgta gagaaatttg attcaaatat agctattgat
    45241 atatttaaag aagaagtggg tttaagtata gaagaaatat tcttagaatt taaagaagaa
    45301 ccaatagcag cagcttcaat tggtcaagtt tatgaaggtg tacttaaaac gggagaagaa
    45361 gtaatcgtaa aaattcaaag accaaatata gagaaaataa taaaatctga tttagagatt
    45421 cttagaacta ttgcaaatac tttaaaagat ttaaaaaaag attttaattt agatttagta
    45481 cagatgattg aagaatttca aactcaatta atgagggaac ttgattatac atttgaagct
    45541 ataaatgcaa ctaaattctc taggatattt aaaaatagtg atgaagtata tatacctaaa
    45601 gtatattcag aatataatac taagaaaatt ttagtaatgg agaaagttaa tggtacaaag
    45661 ttaagtgatg tagaaaaaat aaggagacta ggttataaca caaaaactat tgttgaaata
    45721 ggcgttaggt cattttttac acaggtatta tctcatggat tttttcatgc agacccacat
    45781 ccaggtaata tattcgtagt tgctaaaaat aagatagcat atatagattt tggaatgatt
    45841 ggaattattg ataataaaac tttaaaccaa ttaaatgaaa ttgcattagc aggtgtagaa
    45901 aagaatgttg acaagataat atatctattg atagaaatgg atgcattaaa tggagaggct
    45961 gatattaagg gacttagaca ggatttactt tatctaatac attattacta tgatatttct
    46021 atagaaaaaa taaatgtaac agatatatta aatgaactat ttaggttttt tagacagtat
    46081 aaaatagtca tgcctgcaca atttgtaact cttgcaaaga cagttataac attagaagga
    46141 acaagtagaa ctttaaacac agatttttct tttggttcta tgggaaaaga gtttatgaaa
    46201 catcattata agagtaaatt taaccctaaa aatgttgttt taagttcaag acaaaatgta
    46261 gaagaaatat tactggacat aaaaactatt ccaaagcaat taaaagcaat tttaaaaaat
    46321 atagaaagaa ataatataaa aatgcaaatt gaagatgtta aaatgacgag gttagaaaat
    46381 tgtataatag agctaacatc tcaaatatct ttgagtttag tgttggcatc tattatagta
    46441 ggttcttctc ttataattgc atctccaaat atagaaaata atatatggat aaaatttact
    46501 gcaatagcgg gtttctttat atcctttata ataggccttt gcttagttat aagaagtatt
    46561 aggtcaaaat acaaaaaaga ttagggggaa ttaaatttga aaaaatggat attgaagtat
    46621 aaaggtaaga tagaggaaag tgaatttagc aaaaaactta atatttcccc ggaaatctgc
    46681 caaattttaa aaaatagagg gatatgtact gaaaaagatt cagaaatatt tatgaatcca
    46741 tctttagatt atttaagaga ccctttttta atgaaagata tgcaaaaagc tgttgataga
    46801 ataaagttag cagttgagaa gaacgaaaaa atttggattt acggagatta tgatgttgat
    46861 ggtgtatcat ctacatctat cttgtgctta tattttaaga gtataggtta caatgttgat
    46921 tactatattc ctaatagatt agaagaaggg tatggtataa atgaagatgc tattaagctt
    46981 ataagctcta ggggatgtga cttgattata agtgttgact gtggaattac atcagtgtct
    47041 gaggtcaata cagcgaatga tttgggcata gatgttataa ttacagacca tcatgaatgt
    47101 caaagtgaaa ttccatcagc ctttgcagta ataaatccaa aacaagaaga ttgtaattat
    47161 ccatttgatt cactatgtgg atgtggtgta gcatttaaaa tgattcaagc cttgactcca
    47221 aaagaagaat ttaaaactag tatgtataat tatttggaaa tagtaacact agcaactatt
    47281 tgtgatattg ttccacttat agatgaaaat agaataattg taaaaaatgg tttaaaatca
    47341 atgaaagaag gcaaaaatat tggattaagg gagcttataa aagtttgtgg tgtagaaagt
    47401 gataagatag gttcttctca tataggtttt gcaataggtc ctaggataaa tgcttcaggt
    47461 cgattgggat attcttactt aggagtagag ctatttacta ctcaatcaca agaagaggca
    47521 gtagaaatag ctagtatatt ggaagaaaaa aataatgaaa gacagatgat agaagctaag
    47581 atgtatcatg aagctgaaga aatgctaaag tctaatagca gatacaatga tgacaaggtg
    47641 ttggttttag ctaaagaggg ttggcaacat ggaataatag gaattgtagc atcaaagtta
    47701 actgaaaaat actacaaacc aacaattctt ttaggtatag aaaatgggga ggctactggt
    47761 tcagcgaggt caataaaagg atttaatata tttgaagctc tcataaagtg caaagacttg
    47821 atgactaagt ttggtggtca tgaacaagca gcagggttat ccttggattc agacaatgta
    47881 gaaattttag caaatgaaat aaataaattt gcagattata atttaactga agatgatatg
    47941 atagagaatg taaatgtcga gtttgaatta caagaaaatg taataaattt aaatcttgta
    48001 gaagaattac ataagttaga accctttgga ttaaataatc ctaatcctag atttatagtt
    48061 agaaattata ttttaaaaga tttgaaagtt ataggtaaga atcaacaaca tctgaaatta
    48121 agcatagaaa aagagaaaag ctatgaatgt ataggattta atatgagtca tttaaaatca
    48181 atgtataaag taggagacaa ggtagatgta ctattccaat tagatgaaaa taactatatg
    48241 ggaaatagga aagtacaatt tttacttaaa gatatacgat tggctcgacc taaaagtgca
    48301 agtaatgaca aactttcatt gaaattaatg tcaaaaataa taccaaaaga tactcaaagc
    48361 ctgtataata tatctgtgtc tgattttgaa ttatttgatg gaaatacaga tataaatata
    48421 tttgattatt ttgaaaaaga tacactaata atatctaatt ctataaatgg attttataga
    48481 gcaatgtcag atatatcact tatagatttg gattttaaca taaattacaa tattattgaa
    48541 gatgttagca aaaatactga taaattagag cttatatttt ctcctaatat tgataaaata
    48601 gacttaaaaa gatataataa tattattctt tatgattatt tatacaataa aggcgaatat
    48661 tcgtatatat atgagaataa aagagaagaa agtgaaatta taaaatatta taataaaaca
    48721 gacctattat atttaaagaa tgtagttagt aatatagttc catcaagaga tgaatttata
    48781 acaatttata aacaagcact cataaaaaaa gaaattgatt tggatatggt aaatataagg
    48841 gaaactttta atgtaattcc attaaagttt tttacgatat taaatgtatt tagagaatta
    48901 aatttacttg actttaattt aaattatgaa aaaaattctg tactcataag aatattgcca
    48961 aaaccacaga aaaaattaga cttaaatgag agtttaatac tcaataatct aaaaaattta
    49021 gaaaaacaat acaatagcag ttattaggag gcgtttccca tggatttaaa aaactttata
    49081 aggaatattg atgatttccc aaagccaggc atagatttta aagatgtgac aactctattt
    49141 aaagatggag atgcatttaa atatgcagtg gattctatag ttgaagaatt gaaagataaa
    49201 gatgtagatt tagtaatagg accagaagca agaggatttt tgatgggtac acctgtagca
    49261 tatgctttag gagtaggatt tgttccaatt agaaaacctg gaaagttacc aggtgaagtt
    49321 gagagttatg agtatggatt agagtatggt acagatactt tagagataca taaggatgca
    49381 attaaaaagg gtcaaaaagt agcaatagta gatgatttat tggctactgg tggaactatg
    49441 gaagccgctg ccaagcttgt agaaaaatta ggtggagaag tagtttctat gcaatttttg
    49501 attgagctaa aattcttaaa tgggagagaa aagttgtcta actatgatgt taattctctt
    49561 ataaaatact agtactttta taatagttgg tataacacca actattttca tatatattaa
    49621 aattttatac aaaataggtg gttatatgca tgataaagaa ttacaagaaa taattgaaaa
    49681 aataaaagtt tatgcaccta atgcaaattt tgaaatggtt gaaaaagcct ataatcttgc
    49741 aaaaaaagcg catgaaggac aatatagaaa atctggggaa ccatacttta ttcatccatt
    49801 agcagttgca aatattttaa tagagatgga gttagatatt gaaactataa cagcaggttt
    49861 acttcatgat gttgtagaag atacagaata tacctatgaa gacataaaaa aagaatttgg
    49921 caaagaagta gcggatttgg ttgatggagt aactaaactt ggtcaaataa aatatcgttc
    49981 gaaagaagaa actcaatctg aaaatttaag aaaaatgttt ttggcaatgg cgaaggatat
    50041 aagggttata cttataaaac ttgctgatag attgcacaac atgagaacat taaaatacat
    50101 gcctccagaa aaagcaaagt ataaagcaaa agagacactt gaaatttatg gtggtatagc
    50161 tcatagatta ggaatttcca agataaagtg ggaactagaa gacagagcat taagatttat
    50221 ggacccagaa gggtattatg atttagttag tagagtatca atgaagagaa gtcaaagaga
    50281 ggattatatt caaggaattg ttgaacttct taaagataag tttaaagatt taagtatacc
    50341 atgtgatgta tatggtagac caaagcattt ttacagtata tatagaaaga tgcaaaaaaa
    50401 acataagact tttgaagaga tttttgattt aacagcagta aggatattgg ttgataatgt
    50461 aaaggattgc tatgcagtac ttggtatagt tcatacatta tggagaccta ttccaggaag
    50521 atttaaagat tatatagcaa tgccaaaacc caatatgtat caatcattac acaccactgt
    50581 tgtaggtcct gatggagaac ctttagagat acaaataaga actcatgaga tgcataatat
    50641 agctgaaaat ggtatagcag cccattggaa atataaagaa ggtatctcta gcaaagagtc
    50701 aaaggttgaa gaaaaacttc aatggttgag acagatgatg gagtgggaaa aagatttaaa
    50761 agacccacaa gagtttatgg atgcacttaa agaagatgta tttaatagtc aagtttatgt
    50821 atttacgcca aaaggagacg taattgaatt accagcagaa tcaacaccta tagattttgc
    50881 ctatagggtt catacaaatg taggtaataa atgtgtagga gctaaaattg atggaagaat
    50941 agttcctatt gattataagc ttcaaaatgg taatattgtc gaggtactta catcatctaa
    51001 ttctaatgga ccaagtaggg attggcttaa tatagtgaag accccaaatg caaaaagtag
    51061 aattagacaa tttttcaaga aggaaagaag agaagaaaat gttgaccgtg gaaatacaat
    51121 attagaaaga gaatttaaga agcatgatat accacaaaaa gaccctcttg ttgaaaaata
    51181 tatggcatta gttgctaaga aatttaatca gccaagtgtt gaggacttaa ttgccactgt
    51241 aggttatggt ggtataatgt catctcaagt ggtatctaag gtaaaagacc tatatttaaa
    51301 agaggttaaa aaagctaaaa aggaacaaca gatacaagaa gaagatttaa ataaacacaa
    51361 tataagtgaa acagaataca gtaaaaagag aaagaaaaac gcatcacaag gaattatagt
    51421 aaaagggctt gacaatatct tagtaagatt tgctaagtgt tgtaatcctc ttccaggaga
    51481 tgaaattgta ggatatatta ctaagggtag gggagtagcc atacacagag ctgattgccc
    51541 aaatgcaaac aataatggtg atttcttcca aaatagattg gtggaggttt catggagttc
    51601 agcaggaaaa ggtaagtttg aagcggaaat tcaaataaaa gctattgata gaagaggaat
    51661 tgttaatgaa ataactcata ttgttgcaat ggataaactt agtttaaacg gaataaatgc
    51721 aagaaaaggt aaggatagta ttgtaagtat aaacttactt gtagaggtta atgacacaga
    51781 ggaattaaaa attctaatga aaaaattaaa agcaattcct ggtgtagaaa gtatttatag
    51841 aatgacaaat tagagttaaa ataataggga ggaaactatg agagcagtag tgcaaagagt
    51901 atcttcatct aaagttacag tagatgaaaa cactataggt caaataaata aggggttact
    51961 agtattgtta ggagtgactc atgatgataa atcaagtgat gtagattata tgattgataa
    52021 aatattgaat ctgagaattt ttgaagatga aaatgacaag atgaatttat ctctaatgga
    52081 tataggtgga gagcttttag tagtatctca atttacttta tatggagatt gcagaaaagg
    52141 aagaagacct ggatttagta atgcagctag accagaactt gcaaataacc tttatgaaga
    52201 atttgtaaaa aaagcaaaag ataaaggtgt gacagttggt acaggtcaat ttgcagctca
    52261 tatgatggta gagttaacta atgatggtcc agtaacaata ctattagact caagtaaatc
    52321 tttttaaggg ggaaaacttt aatgattata aaaaaatttg tagatagtta ttttggagta
    52381 aatacttatg tattaggtga tgaaaagact aaaaaatgtg cagttataga cccaggtgga
    52441 agtttagtag agacattaag ttttgtaaaa gaaaatgaat taaatattga atatattatc
    52501 cttactcatg ggcatggaga ccatatagga tatgttaagg atattaaaga aaaaactggt
    52561 gctaaagtag ttgcacatgt tgatgaaaaa gaattattaa atgataaaaa taaaaatcta
    52621 agttatacaa tgagatgtgg agcgcaagag tttgatgcag atatctatgt gaatgataaa
    52681 gacaagcttg aacttggtga attaaaaatg actttcttgc atactccagg acatactcaa
    52741 ggatgtatgt gtataagagt tgaagatgaa atgttcacag gagatacttt gtttgctgga
    52801 agtattggta gaactgattt atatagtggg gattttaacc aaatggaaaa atcacttaag
    52861 aaattatgca aatatgaaga tgctgttaga gtatatcctg gacatggacc aaccagtact
    52921 ctaggggttg aaaagaagac aaatccttac atgtaatttt atattagtat ttaaaaaagt
    52981 ataaaatatt taataactat attagtgagg gggttcttct actgttaaat agaaggagtt
    53041 aagttgatgt tgtatgtttt tttaaaagga catgattata agtatgaagt agcagaactt
    53101 ataaaattgt ttaccagtga atttaagttt aaagactcta atgctaacaa taatatagag
    53161 tcaaagcatt taataaatag attgatttat gagaatggtg tattattctc aagtactgaa
    53221 tactatgaaa atggaaactt aaagtatgag tcaatacaga atataaaaaa tatgaatctt
    53281 gaatttttag atggatttga tagtagcaaa acgattgaag aatttcttaa tagcctagat
    53341 agtgaaagta agaggaactt taaaaagctg tgtaaagaaa atatcaaaaa aagcatgttt
    53401 ttagtgctta aacaagtatt taattcttat gtaccatggg gaattttgac tggtattaga
    53461 ccagtcaaaa ttgtccacaa tttaatggat aaaaagctag atgataatag cataagaacc
    53521 attctaaaag ataattattt tataatagat gagaaaatag atttagctct tgaaatagct
    53581 aaaagagagc gattatttat gtatcctata gataaaaata aaatttctct ttatgtaagt
    53641 attccatttt gtccaactag atgtgtatat tgttcatttc cttcaaattc attaaaacaa
    53701 tttggacatt taaaaagaga atatgtttat aaattgattg aagaaattaa ggggtttgcc
    53761 aaagttatta aggagactaa gaaagaagtt gaaactctat atattggtgg tggaactcca
    53821 actacacttg atgaggaaga attggatttg cttataaatt cattgttcaa tgaattagat
    53881 ttaagtaaaa ttaaagaatt tactgtagaa gcaggtagac ctgacactat tacagaacaa
    53941 aaactaagag tgttaaaaaa acacaatgtt agtagaatta gtataaatcc tcaaactatg
    54001 aatgatgata ctttagtaaa gattggaaga gagcatagag tatctgattt agtagattgc
    54061 tttaatatgg ctcgtagaat gggatttgat aatataaata tggatataat tttaggtctt
    54121 atagatgaag atttaaatat ggtaaagaat acattggagg agataaaaaa actttctcct
    54181 gaaagcctta cagttcatac attagccata aagagagcat ccaacttaaa tataaatatg
    54241 gataggtata aagaacatct aacacaatat gaagaaatgg taaaaatgat agatttatca
    54301 atgaaatatg caaaagatat gggattaaat ccatattata tgtacagaca aaaacatatg
    54361 ttgggaaatt tagaaaatat aggttatgct aaagaaggat atgagtgcat ttataatata
    54421 cagattatgg aagaaaaaca aagtaactat gcattaggtg caggtgctat atcgaaattt
    54481 gtttatgtag atgaagatag aattgaaaga gtagaaaatg taaaaaatgt tgaacaatac
    54541 attgaaagag tagatgaaat gataaaaagg aagaaagaag aggtatataa aaatgttgac
    54601 taaagctcct agaggaacta aagacataac tccaaaagag gcttacaaat ggcgttatgt
    54661 agaaaataaa tttagagaaa tatgtgcttt atatggatat gaagaaatgg taacacctat
    54721 atttgaacat acagaacttt tcaagagaag tgttggagat actacagata tagttcaaaa
    54781 agaaatgtat tcttttaaag ataaaggtga tagagaaatt accctaaagc cagaaggtac
    54841 agcaggtgta gtaagagcat ttatagaaaa taaattatat gcagatactc aaccaacaaa
    54901 attattttat gtgacacctt gttttagata tgaaagacca caagctggta gacaaagaca
    54961 atttcaccaa tttggaatag aagcacttgg aagtgatact ccttcaatgg atgctgaaat
    55021 aatcgcacta gctgttcaat tttttaatga agttggatta aatgatttgg tagtgagtat
    55081 aaattcagtt ggctgtccag tttgtagaaa agaatacaat gctttattaa aagagtatct
    55141 tgactcaaaa gctgatatat tgtgtgatac ttgcaatgag agaagagaaa aaaatccaat
    55201 gagggttata gactgtaaaa atcctacatg taaagaaaat atcaaagata taccatttat
    55261 tgcagaccat ttgtgtgatg attgtaaatc tcactttgat aaacttcaag aatacttaaa
    55321 ggaaatgaat ataaactttg taattgataa aacaatagtt agaggcttag attactatag
    55381 aaaaactgct tttgaaatta tatctaatga tataggagct caaagtactg tatgtggtgg
    55441 aggaagatat gatggtcttg ttgaacaatt aggaggacca aaaggtataa gtggaattgg
    55501 gtttggacta ggaattgaaa gacttttact tacacttgaa ggtaatggaa ttgaaataga
    55561 aaaccctcaa tctacggata tatttatagt aactataggt gaagaagcaa atacaagaag
    55621 ctttaaattg ttaaaagact tgagacaaaa tcatataagt gcagataaag accatataga
    55681 gagaagtgtt aaagcacaat ttaaatattc agataaaata aattcaaaat ttacaatagt
    55741 aattggagat gatgaactta aaaatgacac tgcgacatta aaaaatatga aaacatcaga
    55801 gcaaactact gtaaaattaa gtacattagt tgaagaatta aagcaaaagc tgtaaaataa
    55861 gaaagtatga tgttttgtgt attagataaa tatatagcat taaaattaaa taaaatggag
    55921 gtagtatctt ggaaacttta aagggtttaa agagaactca ctactgtgga gagttgagag
    55981 aaaaaaacat aaatgaagaa gttgtactta tgggatgggt acagaaaaaa agaaatttag
    56041 gtggtcttgt atttgttgat ttaagagata caagtggatt atgtcaaata gtttttgata
    56101 cagatgtaga taaagaagct tttgaaaaag ctgaaaaatt aggggctgaa tttgtaatag
    56161 ctgtaaaagg aaaagtatgc gaaagacaat ctaaaaaccc taatatgcca actggtgata
    56221 tagaaatatt tgcaactgaa cttagacttt taaacaagtc agaaactccg cctatttata
    56281 taaaagatga tgatgatgtt tctgaagcac taagattaaa atatagatac ttagatttaa
    56341 gaaaaccatc tatgcaaaga aatttaaaat taagacataa agtaatgaat attacaagaa
    56401 attacttatc aaacaataga ttttgcgaaa tagaaacacc atttttaata gctccaacac
    56461 cagaaggagc aagagattat ctagtaccaa gtagagttaa tccaggaaaa ttttacgcat
    56521 taccacaatc accacaatta tataaacaat tattgatggt aagtggtatg gatagatatt
    56581 tccaaatagt taaatgcttt agagatgaag acttaagagc agatagacaa ccagagttta
    56641 cacaaataga ctgcgaaatg tcttttgttg agcaagaaga tgttatgagt atgattgaag
    56701 gtttgcttga agcgatattt aaagaagttt tagatgtaga attggcactt ccacttccta
    56761 agatgactta tgcagaagct atgtctaaat atggttcaga taaaccagat actagatttg
    56821 gatatgagtt aacagatata tctgatgttg tttgtaactg tggatttaaa gtgtttgctg
    56881 atgctacaca accaggaaaa agtgttagag gtataaacgt aaaaggcaaa gctgacgact
    56941 ttactagaaa acaaatatca tcactagaag aacatgctaa gacatataga gcaaaaggtc
    57001 ttgcttggat gaaagtagga caagaaggag taacttctcc aatagcaaaa ttctttaatg
    57061 aagaagaaat gaacgctata cttacaagaa tgaatgctga agtaggagat ttacttttat
    57121 ttgtagctga taaaaactca atagtatttg atgctttagg acaagttaga cttgaagtag
    57181 caaataggct taatctattg gataaaaatg tatataactt actatgggta actgagttcc
    57241 cagtttttga agaagatgaa gaaacaggca cattctcagc aatgcatcac ccatttacat
    57301 cacctatgga tgaagattta gacaagttag aagaaggtga taagtcatct ttaagagcga
    57361 aagcttatga tattgtattg aatggttatg aaataggtgg aggaagtgtt agaatatcaa
    57421 attctgatgt tcaatcaaga atgtttaaag cacttggttt tacagaggaa agagctaatg
    57481 aaaagtttgg ttatttatta gaagcattta aatatggtac tcctcctcat gctggtctag
    57541 cttttggtct tgatagactt gttatgttac ttgcaggaac tgataatata agagaagtta
    57601 ttgcattccc taaaaatcaa aatgctgttt gccctatgac aaatgctcct acattggcgg
    57661 aagatgagca attagaagaa ttaagtataa aagttgatat aaaagataat gaataatatg
    57721 tagttgcaag aaactaaaat gtaaaaagtc tggatataaa gtatatttat attcagactt
    57781 tttttattag aattatttta tattttttct ctatatattt tcataaatta tacttgtatt
    57841 ctcaaccaat ataattaaaa tactatgtct aaaaatttta cataaacttg gttgttttag
    57901 aaactacttc tgtaatgagt acacgatttt aattaaagaa tatataacaa atttgaaata
    57961 agtctaatat atgacttaat agattaaatt aaaataataa atttggacta tttatctatt
    58021 tataacttaa attatatcaa attgataaca aactagatat tatacttttt tgtagaatag
    58081 aattacaatt atataaagaa aaattctatt aatagtgaaa aaaaagtaga aaaaagtaga
    58141 aattattctt ttataaagaa agggagggat aatattgcaa gagagagaag aattagtttt
    58201 aaatccagtt ccaaaagagg aaagagttgg atggttagct ccattgttta atatgcttgg
    58261 ttctaacata gctatatctg aactaatggt tgggggaact ttaattttag gaatgactct
    58321 ttctaatatg attattacat caattatagg gaacttaata ttagttgcaa ttattatgat
    58381 acaaggttat ataggttaca aagaagggtt aaatacgtat gtattagcta agggggcatt
    58441 tggagagata ggaggaaagt atcttatatc tctattactt ggtataacta gttttggatg
    58501 gtttggtgta caagcagggg ttgcaggact atcagtacaa aagatattcc caagtgtaaa
    58561 cctaacatta gttacagtta tacttggatt atttatggtt gtttttgcac tgtatggttt
    58621 taaagctatg gctaaattta attacttagt tataccacca cttatgatat taatggtatg
    58681 gggagttttt aaagcttttt ctacttatgg agttgaagct atttataatt atactcctca
    58741 aacaactatg agtatggttg aaggtcttaa tattgtagta ggtcttgtta tagttggtgc
    58801 aattatatca cctgaccagt taagatatac gagacgagta aaagatattt ggattatcag
    58861 ttttttaggt ctagggatta tttcattatt ccaacaagtt gcagctggtg taatgtctat
    58921 gggagcacct acttgggata taacagaagt attggctaat ttaggttttg gatgggtagc
    58981 gtttgttatt ttaatacttg catcttggtc aacaaacgta tcaaatgctt attctggtgg
    59041 attagcatta aaaactattt ttccaaatgt aaaaagaaat gttttgactt tagttgcagg
    59101 tctaataggt acaataatag cagctactgg tataatattt aaatttcagt catttttatc
    59161 tttcttggga atcgcagttc ctgcaatagc aggaattatg tggtgtgagt attattttat
    59221 acaaggaaga acttataagc atagagaagg aataaattgg attgcagtaa taagctggtt
    59281 aataggtttt gcagcgtcgt attatagttc aaaaataaat ttcttaatac ctccgataaa
    59341 tggaattgta gtgagtatgg ttatttatta tatattaatg aaatgttttg gaatcaaaga
    59401 taaataaagg gggcaattac atgggtcgta aggtgaaaat aggtataatt caacaacaca
    59461 gtgtacttgg agatgttaaa aaaaatatag aaaaggcagt agagatgata gatgacttag
    59521 gaaaacaagg ggcagatata atttgtttac cagaactatt tgctacagga tataatttag
    59581 agtctttagg tggagttaaa acattagaat taataagaga acataataag tacatagagg
    59641 aatcaatgtc agaagctgct aaaagaaata atgtatacct gatatctcca tatggaacct
    59701 tagaaaaagg gtctacacat gtttataatt cagcagttat atttgataga aaaggtaaga
    59761 ttatgggaga atactgtaaa aatcatctgt ggtcattaga agcagtatac tttaaaggag
    59821 gggaaaaagt agaggtatat gatgctgatt ttggtagatt tggtgtaatg atatgttatg
    59881 atgcaggttt tccagaagta tccagagaat tgacattaaa aggttctgaa ataatattta
    59941 taccatctgc atggagaata caagatgaag atatgtggga tttaaatgta tctcaaagag
    60001 ctttagagaa cactgtatat acagtaggtg taaatttagt aagtaatgac tctaatttaa
    60061 tactatttgg aaagagtaaa atatgcaatc ctagaggtac tgtaataact caattagata
    60121 catacaggga aaaatatgta ttatcagaga ttgatttaga tgaaataaaa aagtataggg
    60181 aagatatccc ctatttgaaa gacagaaaaa gtagctataa catataattc tatactataa
    60241 tacaagttca atataaaatg ataaaaagag gatgtatcaa tattaagatt aaatttatta
    60301 tactttgata tatcctcttt aatattatca actttgattt aaatattttt aaaatagttg
    60361 ataagaaagt ttttgaacaa caacacagct ttagattcat agttttcgct aaaccatgaa
    60421 agatttaaat atcttttaaa ttcaatatct ttgatatgta acaacttaat ctcagggtct
    60481 tgagataatc cccatgattt tccacatata aatccaactc cttgaagtga ttttataaga
    60541 gcataaattg tatatggtga atcagactca aatgctattt tgggtttgaa attagctgat
    60601 tcacacagga tatcaattac ctctctataa ttctcaccct tcgttataac tataaagttt
    60661 tcatctgaaa cttcgcttag atatacttca tcctttaatg ataaaggatg atttattgaa
    60721 actcctaata gtatttcttc gcatgttaaa gttatgctat tttctgagtt tagctttgta
    60781 aatgaagaag atatgtacaa atcaaaatca ctttttttat aagatgatgg caaagtatgt
    60841 gacacattaa aagtaatatt gggatatagt tttctgaaat tactcaaaag tgatggtaac
    60901 acattagccg ctgcaggaga taatatcttt acttctcctg aattttctaa agaagtgtct
    60961 tgtaactcct tttttgaact ttctactaaa tctaaaatgc tatctactct ttttagaaac
    61021 aatcttccat actcatttaa aacaatatat cttccttttc tgtcaaataa ctgaactcca
    61081 agttcttttt ctaaggaaga tatagttttg cttaaagctg gctgtgctat atttaacttg
    61141 tgtgatgctt ttgttatgtg ctccattcta gcaacagttt gaaaatactt aagatgcaat
    61201 aaatccatag tataaaatac acctctttta atatgacttg agttatatca attttataat
    61261 caactccaca ttatacatta taatataaag tttatataat aaactacaat atattaaaaa
    61321 gttatttaaa ttgttattta tattttgtac ataatctaat taaaaaaagt aactttaaat
    61381 gattaactaa ggaaatgttg ttacaaactt tagttatata aaaaattcat ttgatgagca
    61441 aagtattaat gtcaagtaag aataaaagct tattagataa gaaaaataat attttataat
    61501 aatgatgtta cttaaattat tatgttatac tattttaaat aggaaacatt tagatactat
    61561 aattttaggg ggagtcaaga tgaaattaac taaatcaata tcatcaatgc tgtgcttatc
    61621 tctagtttta agcttatcac cagtagcata tgcaaatgaa ataagtagaa caacagttga
    61681 gaatacttta gtaggtcagg atagatatca aactgctgtt gaagtaagta aaaaaggatg
    61741 gagtagtgca aatgaggctg tagttgtaaa tagtgaatct attgtagatg cattagctgt
    61801 aacaccattt gctaaattaa aaaatgctcc tatattattg acagaaaaaa atgatctaaa
    61861 ttcacaaact gagaaagaat taaaaagatt aggcgttaaa aaagtttata taattggtct
    61921 atctagttct atatcaaatg atgtgcaaaa acagttagaa tctaataatt taactactga
    61981 tagagttggt ggtagtgata gataccaaac agctttgagt atagctaaaa aaatagaagg
    62041 attaaaagat atatcagaaa tagctgtagt aaatgggtac acaggtcttg cagatgcagt
    62101 tagtatagct tctgtagctg ctactaatgg aatggttata cttccagtat ctgatgcatc
    62161 tggtatatct agctttaaag attttataga atctaagaat ataaataaat catacataat
    62221 aggctctact aatgctgtat cagataaaat aaaacaaagt ttacctaatt cagaaagaat
    62281 aggtggagca gatagaaatg aaactaatgg taaagtaata gaaaagtttt atacatctaa
    62341 taaattaaac aatgtatttg tggctaagga tggaatgaaa aatcaaaatc aacttataga
    62401 cgctctagca gtaggagtac tagcatcaaa agaaaattct cctgtactaa tcgtaggaga
    62461 acaattaagt gcaacacaaa agagtgtatt ttcgaataaa aatgctacct ctataactca
    62521 agttggtagt ggaggaaatg aaaatgcatt taaagaatta aaagatttac aggcaaatag
    62581 taacaataag agagtaatgt atgtaactaa tacagataag gtaaatataa gaaatgatgc
    62641 tacaatagaa gcttctgtta taggatatct aaataatggt gatgaagtag aagttttaga
    62701 tgtgttaaaa actggatggg taaaaataaa atacaatgaa ggtattggat atgttagtgg
    62761 gtcttatttg acaaataata agcctgataa tagtaatgaa aatataaaaa taaagtatgt
    62821 aaaagaaaaa gatggtctaa atgttaggaa aggaccaagt acagaagatg aaaagatagg
    62881 tcacctttca tatggaagca aagtagaaac aatagaaatg tttgctactg gatgggtaaa
    62941 aataaagtat aatggtggat atggttatgt aagtaatgat tacttatctg atacaccagt
    63001 tatttaatta taagtaacaa taaaaaactg ctttaatttg taaagcagtt tttttataaa
    63061 aatttaagtc taataactat ttctattttg ataccttaat cctgggattt attattatgg
    63121 atattatcaa catacaaaca ctccaaatcc agtgtctaat tccaaactta gatattaata
    63181 aattcagtcc tgctatggta aataagcagt atttaattac aattaaaagt gtatttatag
    63241 aaagcccctt catagaaagt atcctaaatc caataataga cattctaagt cctataaatg
    63301 ccaataatat acctgcaata tcctgaatta agtaatagta ttcaaatttc atattcaatc
    63361 aactcttctc tgagcagtat caaatatttc taactcttca atttcatcat ctgtgtatgt
    63421 aagcatagta aaaccagtta caccataaat aaatgaaatt ataggtgtaa tccaacttaa
    63481 gaaacaatat ggaataaatt ctagtgggct tacaccaagg gtctgagcac agaaaacagc
    63541 atttgaattc catggtatta atggaccacc aagtgtagct gtatcttcta taattctaga
    63601 tagattttgt ggttttaatt taaattcttt gtatattgga gacattagag ttccgacaaa
    63661 tacagaagtg aacatcattg atgaactaaa tgcatttgca aagtagctta ctacaaaagt
    63721 agacccaacc aatttagttc ttgattttcc tattttagtt ataagaggtt gaagcagtac
    63781 ttctaagaat ccagtttttt ggagaatacc agcaataacg aaaactacaa atactagtaa
    63841 aacggtttca gccatactca ttattccacc acgatttaat agtttgttgg catagacaaa
    63901 tccagtatct atagtaaatc ctgatagcat gtaatttaaa acatcaccta ttttttctcc
    63961 ttcttgaaat actgctataa taagtcccat gatagctgaa cttagtatag atataatggg
    64021 tggcttttgt agcaataaaa gtaataataa aaatattatt ggaatcattg ctactaaacc
    64081 aatatgaaag tttgaattta atacatcctt gatttgattt atttgaacat agtctatagt
    64141 attatttgaa tacttaaatc caattactgt atacagaact atacatatta cgtatgcagg
    64201 tcctgtggta taaaacatat gcttcatatg tgtaattaca tctgtcttac aaactgctgc
    64261 agctaagttt gtagaatctg atagaggtga catcttatct ccaaagaaag caccagaaat
    64321 gactgcacca gctgttaaac caagaggaat acccatacta gtaccaatac tcatcattgc
    64381 tataccagaa gttccaagag tcccccaaga tgtaccagta gcaacagaag ttaatgaaca
    64441 tacgattaat gttgtaagca gaaaatattt aggggttatt attgttagtc cactatatac
    64501 tactgttggt attgtaccag cagctatcca agctgctatt agtacaccaa cagaaagtat
    64561 aattaagttt gattgaaagg catctttacc aacttcaaat ccaaaagctt ctatttcatc
    64621 attagtataa ccaagtttca tggctgcagg aactactata agccatgaaa gtaaaaacat
    64681 tgtagttata gaagcattaa atacaactat accaactgat gttagagcta ttattgcaag
    64741 cattactaac aaggaatatc taaatgaagg tatttttctt tctgtattca ttttcatagt
    64801 gcaaattctc cttaaatatt tttagttaat tgcatttttt attcttataa gagcttcttc
    64861 aagcatactt cttggacaag ctaagtttat tctttgatac ccacttcctc caatgccaaa
    64921 gctgtttcct tgatttagag caactttacc tttttgtaca agtatacttt ctagttcctc
    64981 atcacttaat ccaagtgcac taaagtctac ccataataaa taagtacctt ctggttttct
    65041 aactttaagt tttggcatat tttcatttat atattttata gcaaaatcta tattagattc
    65101 taaatattct aaaaatgatt ctagccaaga ttcaccatta ttatatgaag cttcagttgc
    65161 aactaagcta aagcaattat ttctctttat atcaattctg gtaaaggcat catctaacaa
    65221 tttatagtct ttttcatcag gtagtattac atatgatgat tgaagaccag ctatattaaa
    65281 agttttagtt ggagccatac aagtaattgt atttttttca aattctttag aaatagatgc
    65341 cataggaata tgcttatgtt tttttaatat aatgtcacta tgtatttcat cagatatgat
    65401 ttttacatta tgcttaagac aaatatctcc tagttttttt aattcatctt ttgtccatac
    65461 tctaccaact ggattatgag gattacaaag tatgaataat tttacatctt taatcttgtt
    65521 ttcaatgtct tcataatcca ttatgtagtt tccgttttct agtttttgta atgggcttat
    65581 aattagttct ctattgttat tttttacaac actattaaaa gggctgtaaa ctggttcttg
    65641 tatcattatt ttatcatttg ctttcgtgag ttcatttatt aaaagactta tagctgggat
    65701 aacacctgga ctataaatta accactcact ttttattttc cagttatgtc tcctatctag
    65761 ccagtttact atagattcat tgtaagaatc tggtcttgtt gtgtagccat aaatctcttg
    65821 ttctagtcta ttttttaagg aatcaattat acaaggtgca gccttaaaat ccatgtcagc
    65881 cacccacata ggaagtaaat cattagttcc atactttttt tccatttctg accatttaga
    65941 tgaaaaatta ttgcttctat caacaatctc attaaaatta taattcattg taaatacctc
    66001 cagtaatttt aattttatgt taataatatt aagcaaacaa cgtgccaata ttgataataa
    66061 aaaatattta ttcacaagtt aatatttaat attaagtaat ttcagagcat agataagata
    66121 aaaatattaa ttatacttaa aactttgtgg aaaaggttat ttctaataaa tttttaaata
    66181 tatgaaaatg taattaaata ggttaaatag gtttaactgt ttaacttgtt agacctattt
    66241 atatttttta gaaattctac tccttttgat gttataattg aacctccacg accaataagt
    66301 atgtctacaa gcccaaagtc ttgtagttct aaaagcatat ttctaatctg ttgttctgtc
    66361 aaaaatctat tttcctctaa agctatttta cataagcttt ttctacctat tctttctttt
    66421 aaatcataag ccttttttaa attatccaat ataaatatgt attcatctag tgacttttta
    66481 aaattatagt cgtattccat gatgtttttg tctttgccaa tgttgaattg atactttttt
    66541 atattatcac ttactttatt acaaacggtt ctactataat ttgaatctat agtatccaat
    66601 atatattcag gtaaatcaca tatttctata atatcttttt ccaagtaaca gaagtattct
    66661 cctaagtttc ttaattctct tacatttcct tcccatctat acattttaaa gatttctttt
    66721 acttcctcac ttagaataaa attacatgga atatcatatt ttaatgaacc aaaaatttca
    66781 aatatatcag caggtctttc cctaagtgga tgtattttaa ggggaagaac attcaaccta
    66841 aaatataaat ctcttctaaa catattttta gatacaagtt cttttaaatt tctattagta
    66901 gctgcaatta ttcttacatc aatgtcaatg acattattag aaccaatacg tcgtacttgt
    66961 ttttcttgta tgactctaag taatttagat tgagaattta aatccatttc tccaatttcg
    67021 tctaaaaata tagttccatt gttggctaat tcaaataaac caattttccc acctttttta
    67081 gcaccagtaa aagccccttc atcatagcca aataattcac tttgcagtag attttcttga
    67141 aaagtactac aatttactgc gacaaaagga ccatcttttc tcctagaagc actatgaatg
    67201 gattgagcaa ataattcttt accagtacca ctttcaccaa ttataaggat agatgaattt
    67261 gattgagcca ttttattagc aatttttttt gtattaatag tttgtatact agaacctaat
    67321 atgtcatcaa atgtgtattt actgatatta ccagagttta ctagttgtgc tcttaattta
    67381 gcttgctttt tttctaattg agaaaacttt gtcatcttta gtataaatcc atcaaataca
    67441 tttaattgta tatgtttaat ctctaaattt atatcaatat gatttatttt aatcaatttc
    67501 tcaaaaaatg gagttttatt ggtcaatatg ctttgaaaat tgatgtcttt tatgcaatca
    67561 ccaacaaatg agtcaatcat ttcatttgca tttatagaca aaatttttct agccatatga
    67621 ttatagaatt gaattattcc atcgttattt gtgcatataa ttccatcatc aattatagat
    67681 agtaacaaat caaattgtct ttcaaactta tttgcatcta acaataactc acctgtacta
    67741 taacttgtag gaattatttt ttctacgtat ttttttatta ggtcatcttt tattagatgt
    67801 tttaatttgg tttttgtagc aatttcaaca atacaactta aatctattat tctgtatttt
    67861 aaatctataa cttcacaatt tttaaactta ggcaagattt tttcgccagg agttaggatt
    67921 acagcatctg tgggagtaaa ctcaatctct ggatagcagg gcaggatatt tatattgtct
    67981 attcctaatc tatgtattaa agaaattgtt tctattgcca tatctttact taagttatat
    68041 acataaataa ttttatcttt ttctaatttg gatatcatat caatactgtt cttttcaaat
    68101 gtcaacttgg gaacaatgat ttgagcatca tagtgagata attttactat ttcatcatat
    68161 tttaaataag cagataggag tataagtttt tctttaaaaa actttaaatt tccctcttca
    68221 aatgagtata aatttatctt tagattatca cctaagaatt gccttatttg attttcataa
    68281 atttctccag cgtctttttt taaacttaca atagctaatt ccatttgttt cattttaacc
    68341 tctcatacaa atttgactta ttttagatta cataataatt aaattaaata atattattta
    68401 attattatta taaatttatt atagactaca cattgaagta aaagaagtag ctaaaattat
    68461 tccttttatt tttgtttttt gtatctattt ggtataatag tattagagcg tataataatt
    68521 taggcaaaat tttttaagga agactagagg agaatataaa atgaaaaaat gtctttactg
    68581 taatagggat ataaagtcac caaataataa attagctata aaatatgatg acaatatgaa
    68641 tatatatcca tgtcgtgcag aatgtaagga aaaaattgaa gaatatatag caaaaaaacc
    68701 tacatataag tttataaata tattagaggt tcttttaggt gtgggcggaa tattctgctt
    68761 tttgagtaaa tggactattg cagcccaagt tgtacttgga attgatgcac tggttatatt
    68821 tttattccca ttggcaggat ttaagatgaa tggaaagtta agtatggaac aaactaagaa
    68881 tcaaagtagg tctattgcaa tatcaatttt ggcatttata gtaataataa ctgtattata
    68941 ttttaaacaa gttggtaagt agagcataat tgtataagac atcattagag tatgaggtga
    69001 gtttatggaa gaaagaaaat tagcaccaaa caatgagagg gaagctctca taaaaagatt
    69061 aaaaagaata gaaggtcaag ttaagggtat acaaaagatg gtggaacaag aacgttattg
    69121 tgttgatata ttggttcaaa tatctgctat aaggtctgct ataaatagag taggcacaat
    69181 tatcttagag aatcatataa aaggatgtgt agcagaaagc attaaacatg atgatgctga
    69241 taaaactgaa gagatgataa aagagcttat ggatactata aataaattta caaaataagg
    69301 aggcggttag ttatgaatca acaaggattt attatggaaa ttgttgatga tagaactgca
    69361 aagttaaaaa tgcaaagaca ttcagcttgt gctgcttgtg gaaaatgtgc tactacaaat
    69421 tcagcagagt caaaagaaat attagtagaa gtagacaaca caattggtgc aaaagttggt
    69481 gaccatgtag aagtgagtat ggataatatg aatgtattaa aagcagctgt aatggcttat
    69541 ataatacctc ttatagcact tcttgtagga acaataggga cttattatat attgggggca
    69601 attggaatga caactggagt tgaagccata agtggattag ttggaatttg tcttacaata
    69661 atctgttatt tatacttaaa gaagaatgac aaaaaattta gagacagtag agaatttata
    69721 ccagtaataa caagaatatt aattgatctt taagataatt ataattaaaa aatagcaatg
    69781 tgctttttaa ataaatactc aatacgtatt tgtagagttt aagtacattg ctatttttat
    69841 atttttattt tgattttctg taaggaataa agttttttct gattttcaaa agattcaatg
    69901 ttcttacaaa agaagttaca actaatacac caagtgctat tgcagcactt agaaatagcg
    69961 catctgtacc ttttgacata gccaaagaat aatttttctg aatcaaagac aacattgtat
    70021 tatatagccc aattcctggt attagaggaa gaatacctgg aattacgaac acaatagctg
    70081 gttgctttag ttttcttgct aaagtctcac tgcacgctga gaccaaagca gcagcgataa
    70141 aacctgcaaa aactgcattt gtagtaaaat taaataaata aacatataca atccaaccaa
    70201 ttccgccagt tactccagct ggaagaagta gatatagtgg agcattaaag aaaacagcaa
    70261 atccagcagt tgcaacacct gaaaataaaa aatgcaaaat catagacata tcagtcatta
    70321 gaaaggacct cctattctat accatgtatc aaggacaaaa ccaactccag aagcaattgc
    70381 aataataatc atagcagcat caaaagcacg agaaattcct gatattaaat tccctgatat
    70441 taaatctcta atagctttta taaaagcaac tcctgggagt agtggcatta tagcgccgac
    70501 tataagcatt ttagggtcat ctaaaatgcc tatttcaact agtagaactc ctgaaagtgc
    70561 aattaaaaaa gaagatacta aacaggaaaa tgcagatatt gcacttatct tcatcgtttt
    70621 atcataagta attgcagcaa agattgctat tataaacgta agtataaaat ttaatacata
    70681 attccctcca agcaaacaag caaaacaagc agatgcaatt cctgtacaag agtaaaataa
    70741 ccataaagga taaggtttta catcttggat ttcataaaga cgtgcaatgg cattatcaat
    70801 atcatactct ttgtcactaa caaattctcg agaaaaactg tttaataaag aaatcttatt
    70861 taagtttata cctcttgatt gaatcgtttt cataaacgaa aagccatcaa atttctcatc
    70921 tgaaataatt attactgtag gagttgtaaa aatatttaca tgataaaacc ctcttgacct
    70981 gcatattcta aggacactgt cttcaaccct agatgtttca gctccatttt ttatcatcag
    71041 ttcccctaca aatagagcta gttttagaat atttttctta tattcaagtt cctcattttg
    71101 attcataaat acacctccaa attaaaaaac gtaatattga aattatatca aatttttaag
    71161 taatattcct taatatctat ataaatatat tatctttttt ttgtttcaaa atagtcacat
    71221 ttaaattata tccaattaaa agaattagac aatattattt attatatttt aacttaaaaa
    71281 taaagaaagt aactatgtta aatatggaaa aatggcaaaa cacttgacta ttaattggta
    71341 aaggactata ataataaatt atcatattga taaaaacgaa aattatgaaa tgtctgtaaa
    71401 aataaaattt aaataataac taggaggagt aatatgtttg agaacttgaa aaaagcggac
    71461 cctgagattt atgaaagtat gaaaagagag ttaaaaagac aacaaagaaa tattgaatta
    71521 atagcatctg aaaacatagt atcagttcca gtaatggaaa ctatgggaag tcatcttaca
    71581 aataagtatg cagaaggtta ctcaggcaaa agatattatg gtggatgtga atacatagat
    71641 gaagttgaaa ctcttgcaat agatagaatc aaaaaaatat ttggagcaga acatgctaat
    71701 gttcaacctc attctggagc aaatgcaaat attggtgtat attttgctat gttaaaacca
    71761 ggtgatgttg ttatgggaat gaatttatct caaggtggac atttaactca tggtgctcca
    71821 gttaatattt ctggtcaata ttataaattt tatgaatatg gtatagataa agacagtgga
    71881 cttatagatt ttgatgaagt tagaaagata gcacatgaag taaaacctaa aatgatagtt
    71941 gcaggagcaa gtgcatatcc tagagaaata gattttaaaa agtttagaga gatagctgat
    72001 gaggttggag cattgcttat ggtagatatg gctcatatag caggtcttgt ggctgctggt
    72061 cttcaccaaa atccatgtga agtggctgat tttgttacaa caacaactca caaaacttta
    72121 agaggacctc gtgggggtgt tattctttgt aaagaaaaat atgctaaaga catagacaaa
    72181 gcaatattcc ctggtattca aggtggacct cttgaacata taattgcttc taaggcagtt
    72241 tgctttaaag aagctttaag tgatgagttt aaagaatatc aggtacaagt tgctaaaaat
    72301 gcaaaagcct tagctgaaga acttattaaa agagatttta aattgatttc tggaggtaca
    72361 gataatcatt taatactatt agatttgact aataaaaata taactggtaa agcagcagaa
    72421 aagagattgg atgatgctta tataacagct aataaaaata caattccatt tgacccaaat
    72481 ggtgctcttg ttacaagtgg aataagactt ggtactccag ctgtaactac tagaggtatg
    72541 aaagaagaag atatggcaat aatcgctgag gctatagacc tatgtttaac ttatgatgaa
    72601 gaatctaagg ctagaacatt ggttgttggt ttaactgaaa aatatccttt atatgaagaa
    72661 tataatatta tggattaatt ataaagaaca actaaataaa atacatttaa ataattacaa
    72721 tgattgtgta tgtatttgaa tatatttaga tataaaaaag gtgtctcaaa atgaactttt
    72781 tagtttatga ggcacttttt tgtatggaat cgaacatatt tgtattattt aaataataaa
    72841 aaatatggtt atctctattt ttagatggtc tctttgtatt ttttaattaa aactttaaga
    72901 tttcttaaga attatactag gtttttctaa agatttaaag tctatactta taagtatagt
    72961 aatcacatga aaagaaaagc tttaacgagg agggaatctt atgaaggtat taattcttac
    73021 aggaaaattt ggtatgggtc attactcagc atcaaattct ttaagtgaag atataaaagc
    73081 aaaatttgat aattcagaaa taataattaa agatatattt gagtacatta tgcctaacta
    73141 ttcagataaa atgtacaaga ctttttctat tcttgtaaat cggggaagta gtctttataa
    73201 tttattttat aaatgtgctg aaaatggaaa gaaagatata aaatttactt tttcagatta
    73261 ttttttaaat aaattagata cattacttca tgaagtacaa ccaacagtag ttatttcaac
    73321 ttttccattt tgttctcaat tagtatcaag atataaggaa aaatataact caaatcttcc
    73381 tttaataaca tgtataactg atataagtag tcactcagaa tggattagta aaaatacaga
    73441 ctgttattta gtagctagta aatctactaa ggaagaactt gtttttaaag gaatagatga
    73501 atctaagatt aaagttaatg gtattccagt aaaaaaagaa tttaaaagaa tagaacatgt
    73561 aaatcattca actaaaaaaa atattcttat aatgggtgga ggattaggat tactgcctaa
    73621 atcagaacaa ttttacaaag aattaaatag tttagaagga gtaaaaacta ctgtaataac
    73681 tggtaataat aaaaaaatgt actataaact atatggtaga tatgaaaata tagaggtagt
    73741 aggttacacc aatgaagtat ataaatatat gaaagattct gaccttatta tttctaaacc
    73801 aggtggaata acactatttg aaacaattta ttcagaactt ccaatattgg catttaatcc
    73861 atttttacaa caagagatag ataatgctag ttttatatta aataatgaaa ttgggagaat
    73921 acttggtaaa aataaaaaat actatgtaga tgagataaaa gatttaattt atgatgatgc
    73981 tactcttaaa gaaatgagca gtaacatgaa agaattaaaa aaacaatttg ataataatac
    74041 cttagagaat attttatttt cacttgatga acaaggagcg tgtagagaat gtatgtagta
    74101 ggtttaatta tcgttgttgc attgattttt ttagtccatt caattatacc tacatactat
    74161 aataaactat taaataaaga ggtattaaaa aatatggctg gagaaaatga aattgcactt
    74221 acatttgatg atggtccaga taagagatat acagaaaaat tactagatgt gttaaaagaa
    74281 aatgatatac aagctatgtt ttttgtagta gcaaagaatg ctgaaaaaga gcctgaaatt
    74341 ataaaaagaa tgttgagaga aaatcatata gttggtttac attcattgga acacagaaat
    74401 gcatggcttt atagttatag ttatgttaaa aaagatttta ttgaaagtac aaatataatg
    74461 aaaaatttag gtgtagatgt aaactactat cgtccaccat ggggtcatac taatatattt
    74521 tcaaattcat ttgttaaaaa atataatcta aaaatgactt tgtgggatgt aatggcagaa
    74581 gattgggaga aagatagtac agtagacatt attataaaca agttaatgag tagaacaaaa
    74641 gaaaattcta taatttgttt acatgatgca ggtgaaaatt caggtggtgc agtaggtgca
    74701 cctgagcgta ctattgaagc tttaaagata gctattccaa aacttaaagc cagtggttta
    74761 aagttcgtaa caccagaaag gatgtagtta tgataagtaa aactgaaaag aaaaataaat
    74821 gcctaggtag tgtagctttt ttagttttac taatgggcat aacaggatat tttgttttta
    74881 gagggcagtc agttgaatca ttgataaaat cattaaaagg tgcaagccct atgtttatac
    74941 taattggatt tgcaatgatg tttatatatg ttgcctgtga aggtataaat atatacttag
    75001 gtatgaaagc tttaaaccaa aagactactc ttttaaaatg tatgggatat gcttttattg
    75061 gattttattt tagttctatt acaccttcag catcaggtgg tcaaccagca caagtttatt
    75121 atatgaaaaa agacgatata aatatatcat attcttcact tatactatta gtcattgttg
    75181 ttattcacca agtagttata ctggcatata gtggaataat gttcattatg gaacgtgagt
    75241 ttatattaaa taatgtaagt ggtatgaaca ttttactaat atatggtgta ataacaaatg
    75301 ttgctcttgt cattggagta attgcaatta tattttcaaa aaaacttgta aacaatttta
    75361 taatatcaat aacaaattta ttaggtaagt taagaataat aaaagatgtt gaaagttcaa
    75421 gaaaagttat aatatctcaa attgaagagt atgttaaagg tgctcaatat ataaagcaga
    75481 atccaaaact tgtagtccaa attttagtca taactattgt acaaataaca gctatgtttt
    75541 tagttccttt ctttgtatac aaagcttttc atctatcaac atatactgta tttgagatat
    75601 tagcgataca atccttgctt aatattgctg tttcttcatt accattgcca ggggctgttg
    75661 gagcttctga aaatagtttt atgacattat ttaagatatt tttccctggt cacttattag
    75721 ttccggcaat gttacttagt agggggataa gtttttatgc atttgtagct ataagtggat
    75781 tgatatgtat agtagtacat gtaaaatctt ctgaaaaagt aaaagcagtg aaaaaagttg
    75841 cttatgtaag ataatattat atagattatt tttattaata tgtcaatttg tgtgtatatt
    75901 ttaattaagc tttaaacatg tttacaggag tagaaactat taaaacgtgt gacattgcta
    75961 agcttttgct aataaagtat aatattttat atagtttgaa atatttaaga aatatagcaa
    76021 aaaaaggagc ttggtgatga ataaagagat tccaaaaaaa attttagtag ctgatgataa
    76081 tcctgagatt agggaaatcg tagaaatact tttaactggt gaaggttatg aagttattat
    76141 ggcaacgaat ggagaagaag ctgtaaactt agtagatagt acgattgatt tgattatttt
    76201 ggatgttgta atgcctgtaa aaacaggatt tgttgcatgt aatgaaatta gagaaaaaac
    76261 gacagcacca atattatttt taactgcaaa aactcaagac tctgataaag ttattggatt
    76321 ttcagcagga ggagatgact atttatcaaa gcctttttca tattctgaac taatttcaag
    76381 ggttaagtct ctacttagac gttattatat ataccaggga aaggaaaagg aaagagagcc
    76441 aaatatatta aaaacaaaag agttatgtgt caatttagat actcaagatg ttacactaaa
    76501 tggagaacct gtgtttttga caactataga atatagtata ttaattctta tgttgaaaaa
    76561 tagaaaaaaa gttttttcgt ctgaaaattt atatgaaact atttgggatg agcagtattt
    76621 ttatacagca aataatacaa taatggttca tattagaaat ttaagaaaaa agttagaaaa
    76681 agaccaaaaa aatccacaat atataaaaac cgcatgggga aaggggtatt atattgatta
    76741 acaaaattaa gccatctaag ttgggagtta tactattgat atatgtagta atctcagctg
    76801 cagtggcttt cattttaaat ataccatttt actctgctgt tgaatctata gtaaaagatg
    76861 tatcagaagg gaaagtatat tttaaaagag aagtaaatca acttatggat aattttcaaa
    76921 cttatgtgaa taacaatggt ataagagcag atgatggaga tgatatagca aaatggaata
    76981 gtgataattg gtttgtttct atgaagatat ataaaggaaa taaggttttt tatgatacat
    77041 tatactatcc taatgaagta cctgataaga gtgaggaaaa tgagttttat agcagtccca
    77101 tggctagaaa ctatgagata caattttctg atattaaagc taatatagtt gtagtagctt
    77161 tatttagatt tagatttcaa aattttatag aagcaatttc tattacattt atggcactta
    77221 catttattat aacattttta ctgttgttta gtagaaagat aaagtaccta aggaaaatag
    77281 aaatgggtat aaagatagta gagagtggca gtttaaagta tagaatccca gtaaaaggta
    77341 atgatgaatt atcatcactt gcatctagta ttaatgagat gagtcataca ttggagaatc
    77401 aacttataaa agaaagggag atgaagaata aaaataaaga tatagtaact tcgatatcac
    77461 atgatgttag aactccatta acgtcagtaa tttgttattt agatttgatt aaagaccata
    77521 aatacaatag tcctgagcaa ttggaacaat acataaaaaa tgtaaggtct aaagcatatc
    77581 aaataaaaga tttaacagat gaccttttta cgcattttgt taattctgga gaggaagttt
    77641 caaaagggta tgaaaaaata aatgctaatg aatttatttt tcaattactt ttagatagtt
    77701 catatacatt ggaggagaaa ggatttcata taacaataga aaatgaactt tataaccaat
    77761 atcatattta tgtagatgtt acacaattta gaaggatatt tgataattta tgttctaata
    77821 taataaaata tgctaggaaa gataagccta tagtattttt aattaaagta gaggattcta
    77881 aattactaat tatacaaaaa aatagagtaa gtaatttttc taagaatgta gaaagttttg
    77941 gaattggtat aaagaattgt gagaaaatag ttgcatatca taatggaagc ataaatgtaa
    78001 attcagatga taaagaattt gctattgaaa tatctattcc agcaaaagaa tcataaaaat
    78061 ttaaattata tattgtgtaa ttgcttatgt aaaattctat gaagcaggaa gcatgtgact
    78121 ttagttatgg gatgttcaat attgtgtacc tctaggcaag taacaagttt acttacaaga
    78181 ccatataata ttattatctt aaaaaaaggg gacataataa tatggttttg acaggagcac
    78241 attatattta cattctattt atggtaatta tattaattac tatgattatg aaaaaggata
    78301 caatagtacc atgtatatta ggtgtttttt ttatggggtt gttctttgaa aaaaacattt
    78361 ttggtgctat aacagcagtg tttaactctt ttattatatc tttaaatgag ttgggtccaa
    78421 ttatcttgat tatagctatt atggttgcat tatctaaagc cctagaagcc aataatgcta
    78481 tacagtatat ggtgagacca ttttcgagag ttataaaaaa ttctaataca gcattttttg
    78541 taactggatt tgttatgtta gttctttctt ggtttttctg gccaactcca gctgttgcct
    78601 tagttggagc tgtattttta cctgttgcta tgagagctgg gctaccagca attggtgttg
    78661 cagtagcatt aaatttattt ggtcatggtc ttgccttatc tacagacttt gttattcaag
    78721 gagctccaag tataacagct ggtgcagcag gtgttgcagt atcatatgtt ataaatgatg
    78781 gtatgatttt gttttgggtg atgggaatcg taaccatatc tatggcattt tatacattaa
    78841 aaagagatat taacaaagga atgtttagag aagaactaaa aggttttgaa agtgaagaag
    78901 tagaagagtt taatggaaaa tctaaaatag caactatttt agtagctttg ggatttcttg
    78961 ctgatataat tgctatgtat gtatttgacc taaaaggagg agatgcatca gctcttttgg
    79021 gtggaacagc agtattttta ataataatta taaatgttat aaattttggc aaagatagtc
    79081 ttgaaaatgt atgtgagaat ataattgatg gttttgtgtt tgggataaaa atatttggag
    79141 caattatacc aatagcagca tttttctata tgggtgaagt tgcaccattg acaggtgtat
    79201 ttggaaaagt attagcacca ggttcacaag gtttattatc agatataggc atagctcttt
    79261 ctcaaacaat accacttaat aaatttgccg tatcaggtat agaaactgta gtgggagcaa
    79321 taactgggct tgatggttct ggattttctg ggatttcatt agttggttca cttgcctctg
    79381 tatttggaac tgctataaat gcaagtgttg gtgcactagc tgcattagga caaatcagtg
    79441 gtatatgggt aggtggaggc tgtctagttc cttggggtct tatttcagca tcggcaattt
    79501 gtggagttag tccaatagaa ttggcaaagc gaaactttgt cccagttata accggattgg
    79561 ttgtaacaac catagtagca atgtttatta tttaataaat cgaataaatc tttaattgta
    79621 taaattaaaa atagatgtgt agctataatt tattataatt gttttactaa ttctaagcca
    79681 tacatctatt tttattgata tttttattag tattctttaa taaaataata tttttcatta
    79741 tactatacat aacatctaaa tataacatct aaaatactgt tatctatatt taatatcttg
    79801 ccaaattttt tgatgtttta ttgccctgtc ccaccaacat atataagcta tcacaagttt
    79861 ttacctatac tatcaccaaa caaaaattct aattttaatt tattatttta taacctatat
    79921 tatattaact atattagttt gtagacttta gatgtaatta taaatattaa tactccaaga
    79981 gttcaaattc atatcctagt tttcttgcat ttgatataaa atcatttaaa atttctgtac
    80041 tagttttgga aactgcatgt agtaacaaga tagaaccatc atgtagatta tccattattt
    80101 tttgcgttgc ttcttcatgt gatggttgtt tatcagtatc ccagtctctg tatgcaaaac
    80161 tccaaaatac agtcttgtat cctaaatttt tagtcattgc caagcttttt tctgagtatt
    80221 ttcccatagg aggtctaaaa aatttaacca tatctttccc agttacatct ttatataact
    80281 tttcaacatc atataattcg tcattaaagt tttttagatt gcttgttttt gttggcatag
    80341 atggatgggt tttactatga tttccaacta tatgtccctc agaaaccatt ctttttacta
    80401 aatctttatt ttcttttata tatggagctg taacaaaaaa aactgcttta acctgatttt
    80461 gttttagagt gtcgagtatt tttgtagtgt atccattttc ataaccttca tcaaatgtaa
    80521 gatatagtgt tttttgacca tcttttgtag gtccattgta tagggcatca tagtcagaaa
    80581 atttaaattc aatgtccgta tttacttctg gtgttttatg cttattgttt ggtatataaa
    80641 accaatcaag agtagtgtta tctaaagaag atacatctaa tttattatta tcattattag
    80701 tagtggcttt tgatggttta tctgttccgt ctgaaactat tacattggaa gtatctttac
    80761 cactatctat tttttcctta tcttcttgta actgtgtttc cttattttga ttttcgtttt
    80821 gattgttttg tgaatttgaa catccaacaa taaaaaaaat agaaatagaa agtagtgtta
    80881 aataatgcaa tacttttcta aacattttga agctcctttc taaattaata ataattgcat
    80941 ataataatga ttatatgatt aattacaatt gcatatagta ttattataat tggaaattac
    81001 tattaataat agttatatct ttaaaaataa agtcacaata gtatgacaaa gggtgaataa
    81061 tcaataaatt taaaaaaaaa tgaaaaaaat agttgaccat attatgagaa gatgttatta
    81121 taataaatgt gctcaacaag aagtaacaaa ataacaagca caaagaagtt aattgaat
//
LOCUS       DAMJXI010000010        80004 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.010, whole genome shotgun sequence.
ACCESSION   DAMJXI010000010 DAMJXI010000000
VERSION     DAMJXI010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 80004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80004
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.010"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            <1..1781
                     /locus_tag="PC465_000966"
     CDS             <1..1781
                     /locus_tag="PC465_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2648291.1"
                     /translation="NYLYQIFNVIINSTKLIFNYSWIYIFLCIIFSVFQGFFPIISLL
                     IMQKMINAIQMKNIGQDIFLKLIFIYIVLEMIDLMAVEIYNLYSTTFMKRFTRHIEIL
                     MLEKANRLTTKDFENKEIYDLINRAQSQNGATVIDYFNSWILIFQQAITIFSSIIIII
                     SYQYWIVILIIIAPVIQFYYSQKLGHEQYEISMKRTSEERKCWYINFLMLLGNSIKET
                     ILYGLGNLFINQYGKLKEKFILQDYKIMKKTFEMNFIIIIIGQLFTGVIYFHILLNGF
                     WQKIYMGDVTTYITCITTIKNGIEVILSMMSTIYSKSLYMELLFRFFDIPEKTELNKT
                     KLKIDNIEKIELKHLYYKFTEDSGYVLKDINLELKKNSPIALVGRNGSGKSTLIKIIL
                     GIYDDYEGDILINGINLHNIEKENYYNKISCVFQDYTKYEASVKENVGYGNLDQINNE
                     DLIKESLIKSGLDINQLGSNKLNTILGYWFGENQLSEGQWQKIAISRAMMKDADFYIL
                     DEPDAALDGIAENDMLLTYKKMFENKFGIFVSHKTHHLNLLCENIIVLNNGQIAECGN
                     HEQLIEKEGIYHQLYSSQIISKLETN"
     gene            1810..3237
                     /gene="ccpM"
                     /locus_tag="PC465_000967"
     CDS             1810..3237
                     /gene="ccpM"
                     /locus_tag="PC465_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-rich peptide radical SAM maturase CcpM"
                     /protein_id="HDF2648292.1"
                     /translation="MEQKPFIHLFQTSTGFYFYDVNTDSILNIDENVYDYLKKEQLGE
                     SSSNTLEYVEFLRKQGYLKSNKVKITEHPETEVLKYHCENRVEGIILQVTQNCNLHCD
                     YCTYSGGYINRIHTNKRMSKETAKRGIDYLISHSRDCQYVSIGFYGGEPLLEFDLIKW
                     CIEYSKANIEGKNLKYNLTTNATLITEEIIELFEENNVSIMISLDGPAEIHDKNRKFA
                     NNNVGSFSTIMKKLDMISTKYPNYFKNNVHFNSVLATDNFSCVNKFFTKEELFQNSLF
                     LSSIVSEVNAKVKTEKSQSFYEESQYALFIGYLTLLGRIKKEDSSKLLQTQISTIGDT
                     RNGKQGKQRLVMPEKWHHGGPCVPGVMRLFINVDGYFYPCEKASEASDSMNIGNLDQG
                     YDLKKVEKLLNIERINGDKCHSCWAYENCRICAVSLSVDSTQEDIAKECEYIRSSIES
                     DFQDYCVLKELGFDFETKELIENTI"
     gene            3300..4376
                     /locus_tag="PC465_000968"
     CDS             3300..4376
                     /locus_tag="PC465_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04066 family peptide maturation system
                     protein"
                     /protein_id="HDF2648293.1"
                     /translation="MKKVLIYPFTEEMAPFVKQENLLKDIDITSIVSLKGNGILGDKY
                     KFNGKSLEVSENFDKELEKCTYILLNNFYSDESENIILENIKKAVNHGKKIIFFSNSN
                     SNIDNLKMIIPKEQQFEINSSKNMVKDFQGRIYNIDTPVIFVCSIFEGLEKFDIQLAL
                     RNKLLIDGYKVLQIGTRQVCELFDFYSFPEFMYSNNIEEQDKVLMLNNTLKKLELEKK
                     PDLIIIGIPGGILPFSSKAFGDFGITMYKVLQAVTPDCTILSIPYGKYSDEEISYFGK
                     ITKSKFNIEVDYYNIAAKSILSHPTETMGKPFYLTLGKSLVEKKIATLQNKNVFCLSN
                     KSEIDRLIELMIKEFIKYGTVASI"
     gene            4410..4700
                     /locus_tag="PC465_000969"
     CDS             4410..4700
                     /locus_tag="PC465_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide maturation system acyl carrier-related
                     protein"
                     /protein_id="HDF2648294.1"
                     /translation="MVNTEVMNKLDIYTVLVNIFEKRSKINFDENCYLKNENLFESKI
                     MMPARELVLTLYDIEDYFSISIPEDVILSGRFNSFNNIYDIVKKLENSINFN"
     gene            4742..4960
                     /locus_tag="PC465_000970"
     CDS             4742..4960
                     /locus_tag="PC465_000970"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648295.1"
                     /translation="MSNFGKRNLYDSANGEIDPKGGCNCGALCANLCSCSCSGGTWSF
                     YHTNQVKGSKINNGQQFRSPGEIPGQKK"
     gene            complement(5164..6831)
                     /locus_tag="PC465_000971"
     CDS             complement(5164..6831)
                     /locus_tag="PC465_000971"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HDF2648296.1"
                     /translation="MKNWWKKATVYQIYPKSFKDSNNDGIGDINGIIEKLDYLYSLGV
                     DLLWLTPMYVSPQRDNGYDIEDYYNIDPKYGTMNDFEKLLKEAHKRDIKIMMDMVLNH
                     TSTEHKWFKESKKSKDNPYRDYYFWKDAKPDGSVPNNWISRFSGTAWKYDETTNQYYL
                     HLFEETQADLNWENEKVREECYKILEFWADKGIDGFRLDVVNLLSKTPGLPDDPITGP
                     KGDGRTHYADGPRIHEYLHNMNQKVFKPKNIVTVGEMSSTTPEECINYTRENREELSM
                     VFSFHHMKTDYKGGAKWTNEMFSLDKLKKAQSDFQYKMYEGKGWNALFYSNHDQPRAL
                     SRFGDDRFFRQESAKMLAITLFGLQGTTYIYQGEEIGMTNAYFTKIDEYDDAESKNSY
                     YHMIKSGIDEKEALLILQQKSRDNARTPMQWDNTIYKGFSNHKPWLKVNNDNISVENE
                     LNDSRSVFYTYQRLIKYRKQYDIFTEGTYRLLDENHKNLFVYEREYKNQNLLVISNFT
                     HDNVVYKLPETYLNKLNYTILETNYTRDIIENKMEIKPYESIMIYYK"
     gene            complement(7028..7750)
                     /locus_tag="PC465_000972"
     CDS             complement(7028..7750)
                     /locus_tag="PC465_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2648297.1"
                     /translation="MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNT
                     VRRAISQLNTEGYVQSIKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSV
                     LHFSKILIDNKLSKKTGFKVGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIA
                     QGSIYKYIEECLGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKL
                     FEYTESKHTPETFVFMDVTQRY"
     gene            8141..9568
                     /locus_tag="PC465_000973"
     CDS             8141..9568
                     /locus_tag="PC465_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2648298.1"
                     /translation="MMQQLSLLGKTMLVPIAVMPAAGILGLLFGPNMLNVPAISNISN
                     IVFSNVDYLFLLGAASAYSKSKDKTSVMVAAVVAYMIFKSNLELLNDTLNAGVFGGII
                     VGACIAWTYNKTYKVKVPAFLSFFAGEKCVITLSPVVALILSYIFSLLWIYPQAAMNQ
                     FGFWLGGAGAIGIFLFLFCNRALIPTGLHQVLNAYILFEMGEYTTSTGEVIRGEIPRF
                     MAGDPNAGFFWTGFYIIMMFSIPAISYAIYKTAQDKKKQEVKGAMTAGALTSFMATVT
                     EPIEFSFLFASPKLYIIHSFYSGLGGVVLYLLGARLGSFNGASIIDYVLSFSYGDKAW
                     LVIPVGVVFFVLYYVTFKYIIIKDNVQTPGREVEIEIGDKVSEKEKNLKLSHGNFSYM
                     AKQIIKNCGGYENIVTLNNCMTRLRLEVKDATILNDDNIKKTGAKGVIKLSNTSVQII
                     IGTDVVKVKDEMEMQLDELRKQADA"
     gene            9561..10340
                     /locus_tag="PC465_000974"
     CDS             9561..10340
                     /locus_tag="PC465_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HDF2648299.1"
                     /translation="MHKMKKLVVRADDIGYSEGVTLGIISSYKNGIVTSAGIMVNMPF
                     SRQAIEMVKNDDVCFGLHVNLVIGEPCCKEHIKIKNLLDEGGKFVSSKIRRTQLLTGK
                     EVFNYEEVYEEVCAQIETYKLYMSKLPEYIDIHGIEEDVSISAMCDAAKEYGIPSCPY
                     YLDSCISMPSKYPQNDFYKLNKSFVKLFEEKYINLDKDITLMVTHPGFIDYSLIKSSS
                     LIQERVYEHAMLCDKEVKMWLKRNNIELVDFKDIFKSNNYI"
     gene            10603..11328
                     /locus_tag="PC465_000975"
     CDS             10603..11328
                     /locus_tag="PC465_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2648300.1"
                     /translation="MEFYERAKKYEYKFTDTEDMIIEYMRKNKEEIVKLSIQSLADKF
                     FTVPNTIVRLCKKMEYDGFSQLKNNLKEELKNENKEPKNGFESDIKKTLELIDYEKIN
                     KVADIIQKSRSIIVYGIGQNIPLCEILVKEIRGGHDNITYYSQRHEVLHDIGKLGEQD
                     MFFALSLSGETKEVIEAAKTAVNKGCKVVALTHICENQLQQIADISLYCYSTIKQVNG
                     YNISDKVPIMMIMRAIIEQYWLR"
     gene            11458..13398
                     /gene="mngA"
                     /locus_tag="PC465_000976"
     CDS             11458..13398
                     /gene="mngA"
                     /locus_tag="PC465_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HDF2648301.1"
                     /translation="MEFKKITNENLVFLKQKIKTKKDAIKFLARKLYDEGKLTSYEEY
                     LEAVMYRETLSPTGFERGLAIPHGKSKSVKEAAFAAMTLETPIENWESVDPNNKVEII
                     FLIAVPENEGGNTHIQILSELVTRLSNEDYMNMLLNSKTKKELFNNLDIKEKKEQIKE
                     EIRIQNESKKIILAITACPAGIAHTYMSAEALIKAGKEIGVDVYVEKQGANGMVDPHT
                     PDIIKRADAIIYATDVAPKNTERFEHLPNIKTSVAAPLKRAKEIIYEALEVAQKQGKG
                     DYIEKSSDISYCEKSSWKKDVKSAILTGVSHIIPLIVAGGMILAFAVLASQAFGLQEL
                     YNQEGSWLWQLRKLSGGMLGTLMVPVLSAYMSYSLAEKPGLGPGFAAGLAADLIGSGF
                     LGGMLGGLLAGYIVKFLKKNIPAKGTLAGFVSFWVYPVVGSLVVGLLMLFVVGKPVAA
                     LNNGLINWLNGMTGVNAILLGAIIGAMVSFDLGGPINKAAYTFAIGAIASGNFIPYAI
                     FASVKMVSAFGVTIATVLGRDLFSESEKEIGKQTWILGLAGITEGAIPFMIEDPIRVI
                     PSLVAGSAITGSIVAFFNIGLQVPGAGIFSLALLEGSMSGFIIASIWFFAAVLGAIIS
                     AILLIITRKQKNQRKIHKKIRY"
     gene            13527..16142
                     /gene="mngB"
                     /locus_tag="PC465_000977"
     CDS             13527..16142
                     /gene="mngB"
                     /locus_tag="PC465_000977"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HDF2648302.1"
                     /translation="MKKNVHIVPHMHWDREWYFSTEESRILLVNNMEEIMDMLENNHN
                     YPYYVMDGQTAILEDYLAVKPECKERIKKLVQEGRLIIGPWYTQTDEMVVGGESILRN
                     LLYGIKDCDEFGEYMKIGYLPDSFGQSAQMPQILNGFDIKYSMFWRGCSERKGTNKTE
                     FNWKSDDGSSVLVQILPLGYAIGKYLPMNEDELRTRMDKYLPVLDKGATTDHIILPNG
                     HDQMPIQKNIFEVIYKLKECYPERKFFLSRYENIFKELEKNEDIDTIKGEFLDGKYMR
                     VHRSIFSTRMDIKSANARIESKITNILEPLASIAYSLGFEYHHGLIELIWKEIMKNHA
                     HDSIGCCCSDKVHHEIMNRFFLAEEKVDQLITFYKRRIVDAMSCEMALDKLVAFNLMP
                     YDRNEIVNAQVITKMKAFEIFDKDNNKLDFEVVHKEVIDAGLIDRQIVHYGNYDSFMV
                     YTINFKDKIPAMGYKAYMIKEIGHMLEKAYEVCDMVDNDFYTIQVNENGTLKIFDKKL
                     NKTFENVLLMENGGDEGDEYDFSPLPNEKLIFNDNIVANSTIKKNRFNNEIKINYRLK
                     VPKDIQARKNNRADSFIDFDIVINVPNDKAIIDVVFNINNQARDCRVRTYIPTNIASK
                     FSVSDNQFGHIKRSVYDDAMEVWQQEEWSERPDSIYPMLTFVGLSDKEHGVAVLTNST
                     REFEIVGEKFDTIAITLFRSVGFLGKEEMARRPGRPSGIKLPTPDSQMIGDIKIDLAI
                     VTHEKSTLEANVANMAKEYLTKIQTYNKMPYNAMKLNQSEIEVDYSYSLLKETNKDLV
                     LSVVKKAEKQEALVVRFYNSKEETKSANIVFNKNIKTAKWINLNEKELESISIDNNFV
                     NVECLMNQVKTILVK"
     gene            16402..17556
                     /locus_tag="PC465_000978"
     CDS             16402..17556
                     /locus_tag="PC465_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HDF2648303.1"
                     /translation="MKILISIDSLKGSLSSIEAGNAIKKGILKVKEDAQVKILPLADG
                     GEGTVDALVQGMNGKKETIEVTGPIAKKVDATYGLLKNTSTAIIEIAQASGLTLVPTE
                     LRNPLYTTTYGVGEIIKEAINKGYRNFIVGIGGSATNDAGIGMLQALGFEFYDENNKL
                     VGLGGKVLNEIRHIKIENRLKELDECKFKIACDVNNPLFGKNGAAYIYGSQKGATSEI
                     IEELDNGLRNFSKVVKSYLSKDVANVEGAGAAGGLGFAFLAFLNSKLESGIKIILEEI
                     KLEEELKDADFVITGEGRLDNQTAMGKAPIGVAKLAKKYGVKVIGLAGATTEDAVKCN
                     EEGIDAYFSIVNRAMTIEEAMDKATASENMTSTTTQIFNLITSIQQSKNM"
     gene            complement(17679..19592)
                     /locus_tag="PC465_000979"
     CDS             complement(17679..19592)
                     /locus_tag="PC465_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2648304.1"
                     /translation="MKTSKKELFLNFIKTQHDWIDSSTLANYLNVSTRSIRKYVNEIN
                     SNGEFILSSKKGYKVNLNNNCQTKVDSSENISPDNRLNLILKELIVNSNGINIFDLSE
                     ELFVSPATIEGDIVKANKFIGSYNLKIKQSKFLLKLIGNESAKRKLMSSIIFKETGSD
                     FLSLFDVQKIYQEYNLTKLKENIIYILKKYNLFINEYAINNILLHLMITIDRIKKNNY
                     IESVEVVNYIDNNNDISISRDISNFLESEYNITLTSAELYYLVFQLTNKTTVLNYHEM
                     DTKSLPNYIDDHFVKLTKKIIKNVYDLYLIDLSDEEFVVKFTLHVKNLISRAKNNQVL
                     RNQIPQKLKDSYPLIYDISVYICNQIQTLENVDIDEDEISYISLHVGSFFDRQKLLED
                     KVLCALITPNYYDLQFKIVRDLEKRFNESIEIIQIFSDTHNLDFDNKVDMVITTLPIN
                     DRCPIPFVYVNPYLNRKDYDNIQSKFIQIKDKKNILTVQNHLEMYFSESLFMKNIYLD
                     SAKDYIKFMGNILYENKYVKPNYIDDVLIREKMSSTAFNNNVAIPHSMKMDALKTGVC
                     LIVNDKPVKWGEEKVQIIAMIPINEKEKEKFNYIFESFIEILSEWNNVKELTKADNYS
                     SFMNRIAYLIQNI"
     gene            19834..20151
                     /locus_tag="PC465_000980"
     CDS             19834..20151
                     /locus_tag="PC465_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2648305.1"
                     /translation="MKNIRVLLACGSGASTGFMATSMRKSAKKKGIEADIKARSESEI
                     DKYLSEIDCLLLGPHLDYMKEEIQQKANEYNVPVACISKTAYGRLDGAKALEEALELI
                     SNK"
     gene            20159..21406
                     /locus_tag="PC465_000981"
     CDS             20159..21406
                     /locus_tag="PC465_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2648306.1"
                     /translation="MGRVFMNKFIDFLSEKFTPVVNNMTKNIWVQSVQSTIMKVLPMV
                     FVGSLVTIVSVLKNYISFLPDLSPINQYTFGLLGLFIAFLLPMEIMKNKKFESMSVVA
                     GLAGAGLMLMMIRPEITNEGAIFNFNRFGGEGMLVSLVAGLFSGLIMSLFGSFSFFGE
                     DSALPDFVSKWFDNMLPITVIMFVGWGLIYGLNFDMFEIIVRVFKPVSDIAQTLPGFV
                     LLNFLVVFIYSLGISGWVLSPITYSIQLGAIAANAAAVASGGVATNIYVYEVIQTGWI
                     TLGGLGATLPLVIMMCLSRVGRIKAIGRACIVPSIMNINEPVIFGAPVAWNPFLMLPM
                     WIGTIVISITTYLSMSMGFVTIPSKVFNLWYVPFGISTFMVNQDVRGLIVLAINIVLL
                     FMIWYPFFKAYEKEEIKLESQEV"
     gene            21435..21788
                     /locus_tag="PC465_000982"
     CDS             21435..21788
                     /locus_tag="PC465_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2648307.1"
                     /translation="MTIEEHIIDEELVEVAMQIILRAGEARTEIKHALNDLEKFDYRN
                     ADLKLAKAKGFMTEAHRAQTKIIQGEADGEKRAHSLLFAHAQDTLMTIFSELNITMSL
                     VGIVKSIEYKVNNSK"
     gene            21810..23255
                     /locus_tag="PC465_000983"
     CDS             21810..23255
                     /locus_tag="PC465_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF2648308.1"
                     /translation="MIKLGKFPKGFLWGGAVAANQLEGAWNEGGKGWCLADVHMYDKD
                     RDISKPYESDMTIERIKFAMKDNNGYYPKRSGIDFYHTYKEDLKLLKELGLKCFRFSI
                     NWARIFPNGDDLEPNEEGLKFYDNLINEVIDNGMEPIVTLLHYETPLNLVLKYKGWSN
                     RKVVDFFVRYAELILNRYKNKVKYWIVINQINLIHYESFNSVAFCVDQVDDVEEAKYQ
                     AIHHQFMATALTKKLGKEINSDMMIGMMMADCTSYPEDCDPENVVFALKRNRIQYFFT
                     DVSFRGEYPVYIKRFFKENNINIVIEEGDDKILKENTMDFLALSYYYSTTVSASKNTM
                     NPTDNIKNPYLKANPWGWAIDPKGLYNTLSQYYDRYQKPIMIAENGFGMHDKFEDGKV
                     HDSYRIDYLGKHIEQIGEAIADGTEILAYCMWSPIDIVSCSSQEMEKRYGFIYVDIDN
                     NGNGSKERYKKDSFYWYQNVIRTNGEELREK"
     gene            23647..24399
                     /locus_tag="PC465_000984"
     CDS             23647..24399
                     /locus_tag="PC465_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2648309.1"
                     /translation="MIIELNKSNSENLTKTELEIIKFINENESILPELSIVEIAHETY
                     SSPATVSRAIRKCGLNGFNELRYRLTVKDENDDIQNMGDIINKSFIEAQRVIEQISLT
                     TLINIIKTINKSSKIYILARGLTEYVAKEFSLKLQLLDFNVVFINDPNIMKIKSKSIK
                     KDELIIIFSLNGNTIELVESAQNANLVGAKVITCCCSESAKLIKYSDLYIVGYKHEHI
                     SISEYEVSSRLPLYIISRIIIDYMVRYNNSEN"
     gene            24501..25421
                     /locus_tag="PC465_000985"
     CDS             24501..25421
                     /locus_tag="PC465_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HDF2648310.1"
                     /translation="MIYTLTTNPAIDMNISTNGIKRKLVNRTSNAVYSPNGKGLNVTF
                     VLGHYGIESKILGFFGGFSGKYIVEESEKRGFDVLPTWVEDTTRINIFLNDGSDEFKF
                     VNSGSYVNEKQKLDMLDKIQSLADISYLSISGSLPPGIDDNYYEDIFKICKNKSIKTI
                     LDISSPKLKELLQYNPYLIKPNDEEIKDIFGIIVRDEEDIKDVLKLLHLKGAQNILLT
                     LGEKGSYFYNGKSIYYASAQPVTVVSSACAGDSALAAFLSIWLENPEHIEEALKRSAA
                     TGASVAESNGIGNLENVEDYIKNIRVRKVV"
     gene            25424..27340
                     /locus_tag="PC465_000986"
     CDS             25424..27340
                     /locus_tag="PC465_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HDF2648311.1"
                     /translation="MGKKMILGVTGCPTGIAHTFMAEEALKNSARELGCDIKVETNGA
                     IGVENKLTAKDIEMADAIIVACDKNVDMDRFNGKPVIEVPVKEGIHKANELIQRCIDG
                     KVAIRKGNLSSSKIAEEGNLSFGQKLYKDLMNGVSHMLPLVVAGGVLTAISFLWGIYS
                     FDPNSEQYNQIAATLKSVGGYSMNLMVPVLAAFIAQSISGRAGMLAGLVGGMISFDTG
                     SGFLGGIISGFLAGYLVKLFVHLLRKLPRQLEGLKSIFIIPIVSVGLVGVAMLLLGGP
                     CSALNNAMMNFLSGLQNSSPIILGIVIGCMSAFDMGGPVNKAAYVTGTMLLGQGNYLF
                     MAGVSAACITPPLVIAIASTLFKNRFTEEDRAAGLINYILGSTHITEGAIPFAAKNPL
                     KVLPVLMIASSISSILTYIMKIEVPAPHGGFLVLGLVNKPLLWVGCIFVGSLVGAVLY
                     MMVTPKVVNEKNTIENTNATKDEHKNESAESENVSNNISLYSEETVILDVKGKNKTDV
                     IDEMIGILDKSGVLLDKKKFKEEILKREEISSTGFGMGIAIPHAKTDAVKVPRVAVGV
                     SKEGFDFESEDGSLAHIIFMIAATDNGDNLHLKTLSQLSSKLMNEEFLNELLNSKTSR
                     EIVSKLNNEEIKSV"
     gene            27360..28229
                     /gene="gatY"
                     /locus_tag="PC465_000987"
     CDS             27360..28229
                     /gene="gatY"
                     /locus_tag="PC465_000987"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HDF2648312.1"
                     /translation="MALVTTKQILLDAQEGHYAVGAFNVENMEMVMAVIEAAEELKSP
                     VILQTTPSTIKYAGLDYYLANVKVASEKASVPVAMHLDHGSSFGLAMQALRVGYTSIM
                     IDGSHESYEDNISISKSVVDACMPSDIPVEAELGKVGGKEDDLDGGDGGAYTDPLEAK
                     EFVERTGVSSLAVAIGTAHGLYKGEPKLDLDRLSEIRDVVSVPLVLHGGSGIPDEVIK
                     ESIKRGICKVNYATELRIAYSNGVKNVLNSDPEVIDPKKYGKKGLESVKDFVKSRMEV
                     CGCVGKAIETVKC"
     gene            28739..30202
                     /locus_tag="PC465_000988"
     CDS             28739..30202
                     /locus_tag="PC465_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HDF2648313.1"
                     /translation="MITGELRSKVDKIWETFWTGGLTNPLEVIEQFTYLLFIKGLDEV
                     ETKNEAEATLLGVSFERIFNDEHQHLRWSKFSNEGNSEKMYEIVQNEVFPFIKKLHGN
                     KDSAYAKYMGDAIFKIPTPLMLSKIVDGISNLELSKDRDTKGDLYEYLLSKVATAGTN
                     GQFRTPRHIIDMIVRLIKPTPEDIIVDPAAGSAGFLVSSQQYLRDNHSSLFLVQGLKE
                     HFNNGMFYGFDMDRTMLRIGAMNMMLHGVDNPNIEYKDSLSEVNTDKDKFTLVLANPP
                     FKGSLDYEAVSADLLKVTKTKKTELLFLALFLRVLKIGGRCACIVPDGVLFGSTGGHK
                     SIRKEIVDNHKLEAIISMPSGVFKPYAGVSTAIMIFTKTGTGGTDKVWFYDMKADGYS
                     LDDKRNEIKDSDIEDIIKRFDNLDGEVDRKRTEQSFFVDVEEIRENGYDLSINKYKEV
                     VYEEVVYDAPSVIMGRVKALEKEIVDGLEELERMLEV"
     gene            30206..31390
                     /locus_tag="PC465_000989"
     CDS             30206..31390
                     /locus_tag="PC465_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HDF2648314.1"
                     /translation="MVDEAKILDVVSISGENVKKFDGERSYLSTGNLDFNKISNLEIV
                     TYENKPSRANQTVNIGEVIFAKMKDTKKTLVINKTNKNIIVSTGFYVLKPSKEILPQY
                     LYHYLNSSYFLNQKNRLSKGATQSALNNEGLANIKIRMYNLKVQEKVVRVLDKAQELI
                     DKRKEQIEVLDELVKSRFIEMFGTPSKNEKNWEISEIGKYLDVLTDYHSNGSYETLRD
                     NVTLLDTKGYALMVRTTDLENNNFEKGVKYIDEHAYNYLEKSKVFGGEVIINKIGSAG
                     KVYLMPFLNKPVSLAMNQFMLRFNEDKVNHIFLYNLLLTSYMESKIKEKVRGAVTKTI
                     TKDAVRKINIIVPPIRLQNQFANFVKQVNSLKFEMETSLKELEDNFNSLMQKAFKGEL
                     FN"
     gene            31423..31731
                     /locus_tag="PC465_000990"
     CDS             31423..31731
                     /locus_tag="PC465_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648315.1"
                     /translation="MNQIELDLYHNMVNIYKEADLQCNYKPTRFLQLINNKGALLAAK
                     ELINKEGATEGFTRLWECKRLDLSLEVLVLKEKYKELFTDEEREICINRLKDYGYKFN
                     "
     gene            31764..32144
                     /locus_tag="PC465_000991"
     CDS             31764..32144
                     /locus_tag="PC465_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HDF2648316.1"
                     /translation="MRNIPNEIKNSIINVFPKENTLAIIIFGSYGTDKHTSESDIDIA
                     WIPIKKVPITELATKTEALRNILDIDVDLKIVTDNYTIALKKAILEGEVIYESKDFKD
                     YINKFYFENSDVIDILDWRDMYGN"
     gene            32134..32562
                     /locus_tag="PC465_000992"
     CDS             32134..32562
                     /locus_tag="PC465_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648317.1"
                     /translation="MVIRNKLSWNSIEEVNRDFGSCLYDLQNFKILYDKEEMPELWAR
                     YIKEGFKSYMVSFLELTKAMLYYKSIDLNIKSKNFYDYLLACEYHNLLPKNSSIVIET
                     LRKLRNDDSHGYDIPQFEDMYELFTENEEVFVSIRNSCKK"
     gene            32611..35946
                     /locus_tag="PC465_000993"
     CDS             32611..35946
                     /locus_tag="PC465_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDF2648318.1"
                     /translation="MGNFDFLQKKKNFNSFNTACLEAEKSILVSPSTCATITRRALEL
                     AVKWLYANDSDLVLPYQDNLSTLIHNNSFIELIDYDMLPLLKYIVKLGNLSVHTSANI
                     ERGEAILSLNNLHQFVSWIDYCYSDEYTAEDFNEDLLLYGEEKRTRPDELKNLYERLS
                     SKDKKLEEVIKENEELRKSLTEKRKVNTVNYDFKIDEVSEFETRKRYINIELKLAGWE
                     FGKDIGEEIEVQGMPNESGVGYVDYVLYGENGKPLAVVEAKRTSKDPKIGQQQAKLYA
                     DCLEKRYSQRPVIFLTNGFDMYIWDDYSDRKVYGFYKKSELQLMIDRRKSKKSLSSVT
                     INDEISNRYYQKEAIRAVCEALENKQRKTLLVCATGTGKTRIAISIVDVLSRHNWIKN
                     ILFLADRKALVKQAKKSFTKLLPNLALCNLLDSKDSPEDARMIFSTYPTMMNAIDDTK
                     SKDGKRLFTPGHFDLIIIDESHRSIYKKYKSIFDYFDSYLMGLTATPKDEIDKNTYSV
                     FDMENGVPTYAYEYNKAVEDGYLVDYTSIEFKTKIMEDGIKYDELSDEEKEEYENTFN
                     DDESIGDEIGNNAVNEWLFNSDTIDLVLNKLMTEGLKIEGEEKIGKTIIFAKNTKHAR
                     AIVERFNKLYPKYGGNFVKAVDYSINYVDSIIDDFSDKNKLPQIAVSVDMLDTGIDIP
                     EILNLVFFKKVRSKTKFWQMIGRGTRLCPDLLGVDMDKERFLIFDFCNNFEFFKFNPK
                     GFEGNKAETLTEKLFNIKVSMVKELQDIKYIEGEYAELRKELLEELITSVKALNEDSY
                     IVRMNLSYVHKYKNENVWSNIGAVAQNEIREYISPLITSYSDDELAKRFDVVMYNIQL
                     AYLQNNNASKGIRHVMATAEKLSKLGTIPQIQQQKYTIEKAMTEDFWEDSDIFEVEEV
                     RISLRELIKYLEKSSQKIYYTSFEDMIVAEYRNDSVYNANNLKNYKKKVEYYLNSHKD
                     ELAIFKLRNNKKITKQDVETLEEILLKQLGNCDDYKKEFGDTPVSQLVRRLVGLDREA
                     ANEAFSEFLNNKSFNTKQIHFVKLIVDYVVKNGFIEDNKVLMEDPFRTVGSIIDLFEN
                     HIEERNKLIKTINKIKENASEIG"
     gene            36327..38390
                     /locus_tag="PC465_000994"
     CDS             36327..38390
                     /locus_tag="PC465_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HDF2648319.1"
                     /translation="MKAGEIEFLSYLEGSNKSFVVPVYQRNYNWKKEQCKRLFDDLED
                     IIDSGFRTHFLGSVVSIYSMGKEYLIIDGQQRVTTVSILLIAMCQIIKEFGESKGIIT
                     TEEQIKECYLINKHSRDKDGKIKLKPIAEDRKAYYELFEEEMNTDRNSNIVSNYLYFY
                     NRIKEDNISIDDLFDAIQKLTIVEIELKNGEDDPQLIFESLNSTGLDLSEADRVRNFV
                     LMGRSSKLQEEFYNNYWYKIEKNTSSNVSSFIRDYLTIKERSIPNKNKVYFSFKRYVS
                     DNGIDIEILLKDLLKFSNYYREISYSCTDDNDVNKVLKRINKLEIFVSYPFILELFDD
                     YNEGIINKKVLVESLNLVECFILRRIVCDVPPNALNKVFMNLGREIKKFSDYKENYSN
                     ILRYIFINKKSSQRFPTDSEFSNAFETKDIYNTKSKNKLYILERLENYNNKEIVDLEN
                     LINNNMLNIEHIMPQTLTNKWKESLGDNYKEIHDKYLHTIGNLTLTGYNSKLSNKTFE
                     EKKEMEDGFKDSRLYLNKYISSIDKWNEEEIKNRTKILLDRAVEIWKYPSVTYEPPSN
                     SENIFTLEDDDVNFTNESIVSFSILGESYKAKNWTEFYEQVALTLYDLDSVRFNSIVD
                     KTYKRDFIDNIKSRDAYKLRKGIKISENIYLETNLNTEAKLNIIRFLLNEFDIELNEV
                     IFSIK"
     gene            complement(38607..39173)
                     /locus_tag="PC465_000995"
     CDS             complement(38607..39173)
                     /locus_tag="PC465_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2648320.1"
                     /translation="MDTKKVTFSSMCIVINIVLGMVISMINIPLLFLDTVGTVLGAVV
                     LGPFWGALIGGCTNLVLGVISGPTNIPFALVNIVLGLIVGYISKKKGFGYKEAIITGV
                     ILSIVCPLIGTPISVLLFGGLSGSGADLLVGFLVQSGQKIFTAAFFPRILSNIVDKPL
                     SCIMVVYFISKMPKGFIKQYSKNTSSSY"
     gene            39339..39860
                     /locus_tag="PC465_000996"
     CDS             39339..39860
                     /locus_tag="PC465_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HDF2648321.1"
                     /translation="MKRNREIVVVCHCILNCNSKVEGLSEFKGAQNIAIDLINKGYGI
                     IQLPCPEMIMYGINRWGHVKEQFDNLFFREQCRQMLIHHVRQFDEYLKNDYDIKSIIA
                     IDGSPSCGYNKTCSSKRWFGELSGCNELMDKINDIQMVDGKGIFIEELEKLLKEYNLN
                     IPIVGFDELREDK"
     gene            40659..42737
                     /locus_tag="PC465_000997"
     CDS             40659..42737
                     /locus_tag="PC465_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HDF2648322.1"
                     /translation="MIKISEDYIEKRFDNELLRIEAWGKNSLRIRSFVDQNFVDENYA
                     LNEKPKLNKDDITINKNEDGSAIIKNGKIKAVLDHRDRITFYNDKNEILLKEYIRLRA
                     VKHDDGGEDVGTIEITKDFNSTLKLKSREYRPSYSGEFEVTTRFESEPSEKIFGMGQY
                     QHKFLDLKNTVLELAQRNSQISVPFYISSLGYGLLWNNPGIGKVSFAKNMTEWKMFST
                     NFIDYWITCGESPKELNKNYSQVTGTVPMMPENLLGLWQSKLRYRTSEEVLDVVKEYS
                     KRGIKLSSIAIDYFHWPKQGEYKFDLDYWKNPKELVKKLKEEYSVEPIVSVWPTVQSD
                     AENYNDYLENGYLVNVNRGVRMTMQIQGNTVFVDMTNENAREYVWDRIDKNYKQLGID
                     YYWLDVAEPGYSVYDFDNYRYKKGNVLSCGNIYPIDYLKMIYDGLHNDIESVVTLVRG
                     AWAGAQKYGALVWSGDIDSSFEAFNNQVNTGLNMGLAGIPWWTTDIGGFHGGNPKDPE
                     FRELMVRWFQYATFSPILRMHGDRLPHSKPLSNKGGGSMVTGAPNEIWSYGEEVEVIL
                     TKFIKIRESLKTYLKKLMKEAHEDGTPVMRTLFYEFPEDDKTWEVDNTYMLGDEILVA
                     PIMNYKDRSRKVYLPKGHTWENIFSGVSYEGGKTYEVECPLEEIPIFLKQDSSYNFKE
                     LKNILGEVKS"
     gene            42737..43516
                     /locus_tag="PC465_000998"
     CDS             42737..43516
                     /locus_tag="PC465_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2648323.1"
                     /translation="MEPQLWQLLLIVLYGFFINYEKNSTMFGTYQPVTAGFITGLILG
                     DINTGLYIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTKQEASVGISIGIPV
                     ALLMVQLDVLRNTIGIWLVHKAEDGAKKGNYKNITYMQMLGVLLTAATTGIPVALSVI
                     FGPSLINTILKYTPEWLTGGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVLAVY
                     MKVPLLGVALIGGAIALIIYKKNLENQEQQYTVVGGMDEDE"
     gene            43509..44318
                     /locus_tag="PC465_000999"
     CDS             43509..44318
                     /locus_tag="PC465_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2648324.1"
                     /translation="MSDKVSLNKSNEKVKKSVLWRWFFTSSVSSNYEKMQALAYCYAV
                     LPFLKVVYKDNPEKLQSAVLNHLQFFNTNPWVAPYILGINVAMEELSSEETEEAVASI
                     KTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPFGILLWIVVSVALKLLSIPLF
                     NAGYTSGTKLISSIEKSLKILTESTSILGLMVVGALIPSVVKANVALNFQQGDFTMKG
                     QEILDQIMPGLVPAILVVIVYWALKKNIKPIYLILGVMVVSIILYALGILK"
     gene            44338..44820
                     /locus_tag="PC465_001000"
     CDS             44338..44820
                     /locus_tag="PC465_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2648325.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDAVANNS
                     VQKQVLRMATPAGIASSIITEETAIKNITAGKYEGQNVLLIVKSPVDLIPFVEAGFKI
                     HNINVGNMSSRKDTTVLRPNISVTEEEKEAFKRLLDEGIEITTIMTPDDKKTYLVDIL
                     "
     gene            44841..45245
                     /locus_tag="PC465_001001"
     CDS             44841..45245
                     /locus_tag="PC465_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2648326.1"
                     /translation="MNSIILMSHGNMAEEVLNSAKMIIGDSIDYPTVNMKQDDGIEGT
                     IEKLKKALEVYKESSEIIIMADLLGGTPCNAALLVANNDSRIKIISGLNLGMVIESAF
                     LDTKELAAKLEKIGKDNISMVEQNASLLSDDE"
     gene            complement(45401..46561)
                     /locus_tag="PC465_001002"
     CDS             complement(45401..46561)
                     /locus_tag="PC465_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HDF2648327.1"
                     /translation="MVTDKYTIREMNERLVLEQIIKNGPISRASIASTIGLNKATISA
                     ITKKLIDESLVHEIGIGNSTHSGGRKPILLVFNKCAGISLSMDVGYDYIFSSLSYLDG
                     TIINSKKLTDIQVSKDNVIQLIDEIINSYNISKIDTPYKVIGLTLAIHGITCENKVLF
                     TPYYNLNEIDLYSILSKKYDFPIHIENEANLTALAENTFSTVHNSLLSLSIHSGFGSG
                     IIINNKLYSGRNGMSGEIGHTIIMPNGKLCPCGNRGCLEQYCSEKKVFEQLSSLENIP
                     KIDSDIVKQLYYEDNQNAKKVIHEFCSYLTIAINNAITTYAPEIIYLNSQIISDIPEI
                     LQITKDMLVSSFNKGINIEISSLGSEASLYGGSAVNIKSFLNIQNLTLINEI"
     gene            46769..48319
                     /gene="xylB"
                     /locus_tag="PC465_001003"
     CDS             46769..48319
                     /gene="xylB"
                     /locus_tag="PC465_001003"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HDF2648328.1"
                     /translation="MKLEYVLGVDIGTSGTKTVLFDKLGNTIKSCTYEYPLIQEKSGW
                     AEQDANDWWKAVVESIREVVQSSNISSECIKGIGLSGQMHGLVMLDNEGKTLRNSIIW
                     CDQRTVKECEEITDLVGEERLIEITANPALTGFTASKILWVRNNEPDIYKNTNKILLP
                     KDYIRYKLTGEYATEVSDASGMQLLDIRKRDWSDEVLEKLNIDKNLLGKVYESQEITG
                     YVTRDVASLTGLKEGTIVVGGAGDQAAGAIGNGIVKDGVVSSTIGTSGVVFAYTKEPK
                     IDKEGRVHTFCHAIPNTWHVMGVTQGAGLSLKWFKDNFCQSEVEVSNSLGEDVYEIIN
                     NQVSQVPTGCNGLLYLPYMMGERTPHLDPYARGVFFGLSPIHSKKEIARSIMEGVSYS
                     LKDCMDIIENLNIDVNEVRASGGGGKSKVWRQMQADMFNQDVYTINSSEGPALGVAIL
                     ALVGAGIYENIQKACDAIIKTSTKLEPISENVDTYNIYHRLYKRIYKSLKDDFKLLDE
                     VVNAKINN"
     gene            48415..49752
                     /gene="xylA"
                     /locus_tag="PC465_001004"
     CDS             48415..49752
                     /gene="xylA"
                     /locus_tag="PC465_001004"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HDF2648329.1"
                     /translation="MSEIFKGIGQIKFEGVKSDNELAFRYYNPEQVVGNKTMKEHLRF
                     AMSYWHTLCGEGNDPFGVGTVERPWNNITDPIEIAKIKVDAGFEFMSKMGIEYFCFHD
                     RDIAPEGRDLEETNKILDEIVEYIKVNMEKTGIKLLWGTANMFGNPRFVHGASTTCNA
                     DVYAYAAAQVKKAMEITKYLGGENFVFWGGREGYETLLNTNTELEMDNFARFLQMAVD
                     YAKEIGFTGQFLIEPKPKEPTKHQYDFDTATVLGFLRKYNLDKYFKMNIEANHATLAG
                     HTFQHELNIARINNVLGSIDANQGDLLLGWDTDQFPTNIYDATLAMYEVLKQGGIAPG
                     GFNFDSKVRRASFEVEDLFLAYIAGMDTFAKGLLIAHKLLEDEVFENFTKERYASFSE
                     GIGKDIVEGKVGFKELESYALQMPVIKNKSGRQEMLEAILNRYIYEVDTISNK"
     gene            50275..51474
                     /locus_tag="PC465_001005"
     CDS             50275..51474
                     /locus_tag="PC465_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S41"
                     /protein_id="HDF2648330.1"
                     /translation="MKKKVLFLVIILAFIILLGNSTYSQKNQLSEEEKVDDFNYVYNV
                     VKTGYPYLGVNKRLNNIDWLANKDEYTKRIKNTENDEEFIEELSSILSDLNNKHTEVI
                     DNKKRYELFKKSYSNNDWYDFLNDKKVVDRYDSMNLKIKMPDDIFVKKELILKDVIKG
                     QIGYMYLPSMSSKNGSINNDLKIIGDYINTLEKHKALIIDIRGNLGGSDRYWQGIVSK
                     LIKNDIKINGYRIYRNNNEIVKKYTNARNIKLNPVENLPASVKENAPKEIIKDFNDFE
                     DTSYTIKSTDDSKFKGNIYLLVDRKIYSSSESFAMFCKENKFATLVGETTGGDGGCID
                     PVLFNLKNSGLIVRMASCMYLNKNGICDEEFKTIPEFKVKDCKRTADFKDDNCIRKAL
                     ELENINY"
     gene            51641..52426
                     /locus_tag="PC465_001006"
     CDS             51641..52426
                     /locus_tag="PC465_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2648331.1"
                     /translation="MRLEEMIFFNYNKLNDTDLLIWKYITANKKHCSKMSINELAMKC
                     NVSRATITRFVKKLDLKGFSEFKVLLSWESEKVHVIENQSFDIACNSIIKYVEDQKNK
                     DYDALCKLLYESRTIYAYGSGDIQNVVAKQIKRMFLSCQEIIYDFEGRTFDDSFYNIV
                     SKNDVMIIISLSGENENTLNIARRLKLIGTKIISITEFKNNTLTDLSDESIYISATNI
                     SFLQMHPSYKLTMLYFILIELLFIKYSIYKRHRMITEGIDCKL"
     gene            52595..54160
                     /locus_tag="PC465_001007"
     CDS             52595..54160
                     /locus_tag="PC465_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003233606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2648332.1"
                     /translation="MMKKIQRFGGAMFTPTLLFAFAGIMVGFSIVFQNQSIMGSLATP
                     ENIWYQFWGVISSGAWMVFNQLPLLFAISLPIALAKKQQARACMEALATYLTFNYFVG
                     SMLSFWGKSFGVDFAAEISAGSGLVSIAGIKTLDTGMVGALLISGIVIYIHNRFYDKE
                     LPDFIGLFRGSSLVVAICFFVMIPVALLTCFIWPHIQNVIRHLQTFFINSGNIGVWCY
                     AFLQKILIPTGLHHFVYAPICYDSVVVPGGTSVYWATHIQDFQTSAKTLKEMYPIGFS
                     LSGLSKVFGSLGVFGAFYVTAKPEKKKKVLGLMIPATLTAVLTGITEPLEFTFLFVAP
                     LLFLVHAFLDACLQTISFALGVVGDFGGGIINWVVLNWLPLGMYHWKVYVVQVVVGII
                     FSFIWFFVFTFLIKKFDMKTPGREEDSEETKLYTKNEYLETKDEKGNKLSKASQQASE
                     YIKLVGGAENVVDVTNCATRLRLTLKDDSIISKEEDFKAVGAHGLVHNGKAIQIIIGL
                     SVPSVREEFENLL"
     gene            54174..55505
                     /locus_tag="PC465_001008"
     CDS             54174..55505
                     /locus_tag="PC465_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF2648333.1"
                     /translation="MERKRQRILIAGGGSTYTAGIVTMLIESVAKFPIESIKLYDNND
                     ERQRKVAEACAIIVREKNPEIKFSYTTNPEEAFTDIDFVMAQIRVGLYALREQDEKIP
                     LKYGVVGQETCGAGGIAYGLRTIGPIIEMIDYMEKYSPNAWMLNYSNPAAIVAEACRV
                     LRPNSRIINICDMPVCLEEIFARVLGLNSRKDFDVRYYGLNHFGWWTSIKDKEGNDLM
                     PKVQEYCAKKGYEEFTPQGQHKESSWLETMRAAKDLLEIEPTTLPNTYLKYYLMADET
                     VEHANPNYTRANEIMDRREKDTFEECERIIKNGTARDTWFDASEHSQFIVELACALAF
                     NTQERFLLIVPNNGAIENFADDAMVEIPCLVGKDMVEPMSIGKIPTFQKGLMEQQVAS
                     EKLAVEAWIEKSYQKLWQSFTMSKTVPSAKVAKEILDEMIVANKDFWPTFK"
     gene            55519..56007
                     /locus_tag="PC465_001009"
     CDS             55519..56007
                     /locus_tag="PC465_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648334.1"
                     /translation="MITNKIKNITAVLKDENIFLSVVMVCFLILPVLYIVYLELTSLF
                     TNISFSQLLNNDVNASLNLISNFSAVYSAYVIYNIKKNKEIKENMIAFYLVLLGQIFQ
                     IYTITIVIMFTYIYKFVGIKQIISSIKELQWGKSYKALFSSIAVCLISLFVMIIRIKL
                     IM"
     gene            56021..56488
                     /locus_tag="PC465_001010"
     CDS             56021..56488
                     /locus_tag="PC465_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2648335.1"
                     /translation="MFFKRKKEAITINSYIDGKIINLGEIPDKVFSTKVMGDGFAMIA
                     KDNILKSPTKGVISFIAQTNHAIGIKLQNDVQILIHIGLDSATTKKENFKLEVKQGQE
                     VNMGEKLVEIDNKLLENTLYIPLVIVENPNTVKYHLSNLNQEGNSGIKVINFD"
     gene            56491..57645
                     /locus_tag="PC465_001011"
     CDS             56491..57645
                     /locus_tag="PC465_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2648336.1"
                     /translation="MINKAIKFKFIIFYFFSYIIFAFASTKFTPFLSKLGYSAFERGI
                     ILSSYAITNILFQLLFGVLADKYQTMKKIVLISLSVYGIASVIMFSTESATFIIYLLL
                     VALSGGLLNTCCSLYDTWIIGCGDNINNYLSFIKTFGSIGWAIGSMVASYLILRFSYF
                     GLSVAIGLIVVLLIINILLLPDIEKINKKINVTNKDIIELLKDKKYILLVCILFLLYS
                     MVVANNCTVIDKMIALNATNSQISLKWSLQSVLEIPTYLAGSYLLKKYSSLNLLKLSA
                     IMITVQFLLFALTNDSNIIIILCVFQVFSTPLILITSKRLIFEVSPKKLRSSSQLIAL
                     SIFMGGSSLIIPTVAGFLSINIGYNYTLMVLSLFGCLAYCLIVLLNYLQE"
     gene            57928..58653
                     /locus_tag="PC465_001012"
     CDS             57928..58653
                     /locus_tag="PC465_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009003081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2648337.1"
                     /translation="MLKNYGIKGFKTNVLKNISLTVNEGDFISIMGPSGAGKTTLLNL
                     MSTLDKQTSGEIILDGINISKVKNNELSKLRREKIGFIFQDYNLLDNMKLMDNIALPL
                     ALGKKKSKEIEAKVFSIAKKFGLENHLDKYPYQLSGGQKQRGAAARSLITNPTVIFAD
                     EPTGALDSKSAYELLESLEKINRENNATIIMITHDPLTASYSNEVYMINDGNIKCKLN
                     KGNSRKEFYGKIMDMLASMGGEM"
     gene            58654..60561
                     /locus_tag="PC465_001013"
     CDS             58654..60561
                     /locus_tag="PC465_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2648338.1"
                     /translation="MSILGIAYNNFKSNIRTYLAFFISMVFSVVVLTNFELLRYGDAI
                     NVLQDENKKFTLSVLVAVIMILSVFLFFFIWYATNIFFKNRSKEIGILSFMGLDLYTI
                     GKIYFVENMLIGISSCITGIIIGIITSRFFQVVIIKLSGFNIKVSNGLSIEAILYATL
                     IFISIFIIMAVKGFITICRSSVINLINISKKQEKIPKVGIGIYILAIVSIIVIGYGYY
                     LSTNIRTGDITSVLPVIGIIIVGTYGLFKSVMPVIFDIIIKNKKILFNGNNIIAINNI
                     NYRLNKNYKTYAIIAIIITTTISTLGASVAMKRIHKNAQEQRNVYTISIVSMDKDEVN
                     KKQIENIIKDTNKIKYSVNPELTILKKTDIKEAYDTTDTIMKYSDFCNTLKVNGNDKE
                     LKEYGERLVSGNNVIELKSPQTIASIATKEAKIKLDGQLYNISRGEVKVPVLGTGLNQ
                     SIIVVNDDTYFKLRDKGQQVYFYGAKVFQEENSQVMFNNIEKNLSLKNVYIQNGYKAQ
                     GESQWMKFAYVVLVFLFLVFAIVAGSIIYMKIYSDAYEDKEKYKILLKIGTTEKDINR
                     AVLKEVAIFYTLPMLSATISSYFALRLAGDLLMTDLFGIYILSLVICLIIFIIYGAVS
                     VNKFKSVVYKN"
     gene            60713..61393
                     /locus_tag="PC465_001014"
     CDS             60713..61393
                     /locus_tag="PC465_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2648339.1"
                     /translation="MYRILLVEDDIDLSKEIALAFEKWGFKVELIDDFEVVLDEFIDK
                     KPDVVLLDVNLPLYNGFYWCEKIRAISNVPLIFLSSRDSDMDLIMGINNGADDYITKP
                     FSIEILVTKINGIIRRVYNYSDSNSILYCEDLMFDVGKGIIKHKYKDKSIELTKNEIK
                     ILTLLLKNKNRVVSRESLMMTLWDNDEFVTDNALTVNMNRLRSKVKELGFDDFIKTKK
                     GIGYIIQC"
     gene            61387..62406
                     /locus_tag="PC465_001015"
     CDS             61387..62406
                     /locus_tag="PC465_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2648340.1"
                     /translation="MLVKYLKGRSKYIALPLVVVSIINIYLFAIDIFKNKYSELIYLD
                     FLVLFIIMVFFVIDYINFRNSYTNLYNCIENSGEIDSYLVDGQSFEENLIKDIIENLK
                     IKNNSDIETYKQSLKELDEYIAKWVHEIKIPISSLSIITDRLSSIEDSLDIKNQVAKI
                     NFLVNSILYSSRSNTMFEDVFINKFNLEKLVKMSIKNNSFLLIKNNIEVSLNELENDV
                     YTDSKCMSYVLDQIINNAIKYSKEVGKIEFNSKKLENGVVLSIKDFGIGINEEDISRV
                     FDKGFTGKNGRNQLYKSTGMGMYFVKKMIDSLGHEIEVCSENGSYTIFNIYFYDISDY
                     LSLDS"
     gene            62837..63997
                     /locus_tag="PC465_001016"
     CDS             62837..63997
                     /locus_tag="PC465_001016"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HDF2648341.1"
                     /translation="MITMYSVGLMSGTSLDGVDAVLAEISGNGRNTKVKQIEFITLEI
                     PKDIKDEIRKCCIEEESSVDLICSLNFKLGYLFSKAVKSVCHKANFHIANLDFIASHG
                     QTIFHIPRSYNNFVSSTLQIGEPAVIAYETNTKVISNFRVMDIAAGGEGAPLVPYSEF
                     LLYSDNNKNLALQNIGGIGNITIIPKSCNIDDVFAFDTGPGNMIIDGVCQRLFNRKYD
                     KNGYFASKGKINEEMLKDLMSHKYLSQAPPKSTGREIFGQVYLDNMLNKYKHVDKYDL
                     IATVTMFTAKAIYYNYKNFILPKVNVDTLLIGGGGAHNLTLIGYIKELLLEVEVLTQD
                     EYGYSSDAKEALAFVILGNETLNNSFSNVISATGAKNKVILGNITPKPFGGK"
     gene            63999..64397
                     /locus_tag="PC465_001017"
     CDS             63999..64397
                     /locus_tag="PC465_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648342.1"
                     /translation="MSNNKKKKRKKNNNYKNAKSTKSNKNTKKEMEKNQRTDYNIPTI
                     SFKSGLILIVSSLVSTVVFPLLLSIFGIDNRFGVVIGNSLITSFAVAYTRYFVETKRG
                     FSLGFFRLYILFALSFAIIGYFWIYKGIHI"
     gene            64659..64967
                     /locus_tag="PC465_001018"
     CDS             64659..64967
                     /locus_tag="PC465_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2648343.1"
                     /translation="MRVLFVCSSGMSSAIAVNALQKEGAKNGIDIDVLAVGTQEFEDE
                     VKNGWDIAMVAPQVRHRFDYLKAFADEVSVPCALIQAQAYSPLGGPKLLKQVQELLSK
                     "
     gene            65056..66402
                     /locus_tag="PC465_001019"
     CDS             65056..66402
                     /locus_tag="PC465_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2648344.1"
                     /translation="MLDKFTEFLDTKLSTSMARLAEQRHLRAVRDGIVASLPLIIVGS
                     FFLILAFPPLPDSWGVTQYLKENAVTILLPYRMTFFIISVYSTFGIGYSLAKSYKLDG
                     LTGGLLATATFLLTIVPTAIEGLTPDLLKIVEKSPELLAWYNSIPQGWQMPMANLGGG
                     SMFVAIVTSIIGVEIYRFTDKSKFKITMPEAVPASVTRSFEALTPAALIIILMAIVTY
                     FLGFDWHGFIAKLVTPLVSATDTLPSVIILIFLITFFWSFGIHGVSIIGSLARPLWIQ
                     LLDANTASYAAGQAVPGIAAEPFFQWFIWIGGSGATIGLALLLAFRAKSAYGKSLGKA
                     TVIPAIFNINEPIIFGAPIVLNPILIIPFVVAPIVMATVSWFAMSANLVSRVVVTAPW
                     TLPGPVGAYLATGGDWRASVLNLLCIAISIIIYYPFVKMYDKRLLHEEKVEEQEAY"
     gene            66635..67732
                     /locus_tag="PC465_001020"
     CDS             66635..67732
                     /locus_tag="PC465_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDF2648345.1"
                     /translation="MGRLGISIYPEKTTSKEIYDYIDKAAENGFTRIFSCLLSVKDTK
                     ENIIKKFKRINEYAKFKGFEVILDVNPRVFGELEISYKDLTFFKKTKADGIRLDMGFT
                     GSEEALMTFNPQNLKIEINMSNNTNYIDTIMDYQPNKENLIGCHNFYPHRYSGLNLKH
                     FIKCTERFNKYGLRTAVFVTSQNETTFGPWPVTDGLPTIEMHRNLPIDIQVKHIIAMN
                     NINDIIISNCYPTYEELKVLGSMRKDMVTFDVAIEENIREVEKKILFEEIHFNRGDIS
                     DSLIRSTQSRVKYKGYKFELFNTPKIIKRGDIVIESSEYGHYAGELQIALTDMKNSGK
                     SNVVGYIRKEELFILDYIKPWQKFNFKPSTK"
     gene            67831..68745
                     /gene="murQ"
                     /locus_tag="PC465_001021"
     CDS             67831..68745
                     /gene="murQ"
                     /locus_tag="PC465_001021"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HDF2648346.1"
                     /translation="MLIKTLENLVTEGRNKNTLQIDKEDTLGIIELINNEDKTVAYAV
                     EEQKESIAKAVNIIVDRMKQGGRLFYIGAGTSGRIGILDATECPPTYGVDFELVQAII
                     AGGNQAIFKAIEGAEDDKELGKQDIIDRGVTSKDVICGIAASGRTPYVIGAMEYAKEL
                     GCAVLSITMNPNSEMSKKADLPINIIVGAEVIMGSTRMKSGTAQKMVCNMLTTASMVK
                     MGKVYSNLMVDVKTSNEKLVERAKRIIMIATNVKYDVAEKFLEEADNSVKLAIFMIKS
                     GLDKDSAKSILDRQEGYISEALKSIEKL"
     gene            68855..69775
                     /locus_tag="PC465_001022"
     CDS             68855..69775
                     /locus_tag="PC465_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA reductase"
                     /protein_id="HDF2648347.1"
                     /translation="MYFLGVDGGGTKTTFTLVDEELNIVGTITKGTCHYNQIGFDNLT
                     KLLITGLEEVCKDAKINVEEITYAFVGLAGYGKIKEVLYALEVATKNAYSHINYTLGN
                     DVEIALAGSLNGEKGINIIAGTGSIAQALDKDGNLHRCGGWGYVLGDEGSAYYIGMAT
                     LKMFTMQSDGRCSKTKLYDLIKRHLNIENDYDIIKYVNDEIQGDRIEIAKFATICLKA
                     VIEGDNTASKIFDDAAYELSRLIIGLDHHFEQGTKIKVSYSGGVFKSGDLILEPLKKY
                     LNKTRFGIVRPVLTPDLGACLLAKKKYYSK"
     gene            69792..70643
                     /locus_tag="PC465_001023"
     CDS             69792..70643
                     /locus_tag="PC465_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2648348.1"
                     /translation="MSCILKLKQIYEDLTEVDKKIADYILNNTEAISKLSVSELASNS
                     KTSTASIVRFSRKMGYSGFGDLKIEIAKDLMGKENEYTYVDENYDCNIDSVINKITNK
                     NIETINQTRLLNEKDIIKEAVEQIIKAKNVYIFGVGGSALVALDLQMKLLRINKQAFT
                     SLDSHTQLMVSSNVDKEDIAIAISYSGESKEVIKSIENAKLKGCKVICITKYSDNHLS
                     KISDLKLVVPNIEKRLREGAISSRIAMLTLIDIIYISIIQENLNEAEQKLQETKRILD
                     YLNINNA"
     gene            71255..72316
                     /locus_tag="PC465_001024"
     CDS             71255..72316
                     /locus_tag="PC465_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HDF2648349.1"
                     /translation="MKKIRKLATKLLITTIVLISGMSMTVYGMTAKEVTAKAPKSYVT
                     GTNSVYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKILVAYNHIKNNTTYVDWNA
                     VEGANTAYTLVTKKGACSGMARSMKALCDAMGIESYYVHSTSNDHQWNLIRFGDGRLY
                     HVDIDANKSAGKDIIYKSLSHPLPFDKTAYPKVGAIVQTVKPEQTQKPAPPGKHTMLP
                     HQEGAKAVGNFGKKGEDINEKHVMYEGVRCSVVNSSVNTITFTGSESNLDPSNLTIAV
                     IGFMNTPYGMFALAPEGKPVEYPFKYDKPFSLDFSGKNRSGAELAKYCKKNDVTIKIE
                     ITDEKANIGLGQIMYVRYE"
     gene            complement(72432..73406)
                     /locus_tag="PC465_001025"
     CDS             complement(72432..73406)
                     /locus_tag="PC465_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648350.1"
                     /translation="MNNINSLKVIKLSLGCSLAIFIAWLLKLEYSMVAGVIVLLTVKD
                     TKRETLKGSIGKIYGFLLCTIFSYLCFNILGYNLTSFSIFIFIIIPLCFLLNIQDVIA
                     MCVVIASHYYLQGETSIKWILNEAGIFAVGTGIGVLINMYIPTNIHKIHEVQKKLQEE
                     VSIVLIDIADIIVNPKKENGYSRDLYTLNSLIDSSISETYDNINNTLLSDTRFFLEHM
                     DIIKSQRDILENLYSYVSQLNSTPPQAHILSAFIHKIGYTEFEAETGNLLLEELKRLM
                     LSMKNQPLPVDRTEFENRAILFLCLTELKQFLVNRKHAQMLRDNNFYK"
     gene            73862..74743
                     /locus_tag="PC465_001026"
     CDS             73862..74743
                     /locus_tag="PC465_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline iminopeptidase-family hydrolase"
                     /protein_id="HDF2648351.1"
                     /translation="MKITEGYMPFKGFKTYYRIVGENTEGKKPLVLLHGGPGSTHNYF
                     EVLDKIAESGRQVIMYDQIGCGNSFVEGHPELFNADTWIEELIELRKHLGLDEIHLLG
                     QSWGGMQAIWYAIEYKPKGIKSYILSSTLSSAKLWEKEQKRRISYMSEVDQKALLDAV
                     NTGDYSSKEYNDALERFMEMYCAGEVTEDSPECLRRPKKSGSEAYIVGWGQNEFSPTG
                     TLSGYEFTDRLHEIKEPCLVTSGAIDLCSPYIAKTMYDRIPNSKWELFEYSRHMPFVE
                     ENEKYIKVLTEWLNAND"
     gene            75125..75928
                     /locus_tag="PC465_001027"
     CDS             75125..75928
                     /locus_tag="PC465_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648352.1"
                     /translation="MEKLRVIEMIKNNPNIIATIDNPTDEMKLLAIKENGLVLEYINN
                     PTREMQELAIDNNIRAIKFIDNPTEDMMIKAVNEGWSILDYIKNPTDKVIEMAINQAG
                     WAIKYAKNPSEELQLLAVRKNYDSIKFIKQPYESVQEEAVRISYDALRYIDSPSYNAE
                     LIAIKNNEAAISFITDLDKNKMLEFLKVNILVIKYILKKVSKDELESVLKEVLSKEDV
                     EEKYIRDFLNCSVIDRNSESIPIDKIMFIYKYGSKTAKKIAVDEKLKIM"
     gene            75940..77070
                     /locus_tag="PC465_001028"
     CDS             75940..77070
                     /locus_tag="PC465_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2648353.1"
                     /translation="MNFIDTLKSVDLILSTGEVPLIVGESGIGKTALANKLAKENDWS
                     LIVIDGNLLKEGEIGGLPTIESYVGVNSNGYKTEKKTTVYAVHNKLREIDEEISKSKT
                     VLLFIDEINRCEHTVQQELMNLILNREINGYKLHDDVKILAAMNPSSKYGSDFDYQVV
                     DMDAAQENRFVWLNMESDHTQWIKWAIDEGIERKVIEFISTFPEYLHKINEDDVRATP
                     RSYERVSKIYKVYKEKNNSIPRAVFLNVVKGNVGKVIAEEFISFIESNSEPLISYEDV
                     FLGESIDESIVERVKNESHTRLYLSAMNILKDLELNIKNDKYESNHYINRFIEFLKMY
                     PVDLMIGIMKDIRNSYIEVYKKAIENEEFVKSYFESYSLIRG"
     gene            77074..78483
                     /locus_tag="PC465_001029"
     CDS             77074..78483
                     /locus_tag="PC465_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648354.1"
                     /translation="MENYFDKQAKELYNKASEIINTHSMLKANRANEKFDIDIPQDFK
                     YEFFSLVDKVNLSLMEEEDNFYGYFLFQMSREIRFDISSPTGVNFKGAKYVIYFNPII
                     FLTLDIKQMETTIKHEIHHILSMHLMRAKELKGKYSTLAINMAMDIVVNKFLNNLPPY
                     ATTLEWVNLKYSLKLEPYEPFEYYVEKIQTELDLMEVDEDGEEDDSDKYGDIEIDYSP
                     ERTHDIWDESNEIDENTLREFTEKFINSSQKGKVPAYLESMISSLKNSKGELPWNLYL
                     NRIMGTVENNKKKTITRRNRRQPNRLDLRGELRSHKSEIAVALDVSGSISDEEFKQAI
                     KEVLSIVKNYNHEITIIECDNEIRRVYKVRTEKDIKDRIRIGGGTRFSPVFEYANNKK
                     INLLVYFTDGKGENKLQVIPRGYKILWVISGRGDKISLKEPYGAVKKLTKVKTNDEIL
                     EINDVRNDGYSMNSQAPIL"
     gene            78694..79203
                     /locus_tag="PC465_001030"
     CDS             78694..79203
                     /locus_tag="PC465_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HDF2648355.1"
                     /translation="MVMFLFKIDDYIMYGMTGVCKVMDITNERFTNGIKKEYYVLSPI
                     YSNNTVIKIPVDNEKVPMRKLLSKINVLSLINDIPNMDTSWIDNEKLRSEQFKKILRG
                     GKCEELIKLVRSIDNNREYVKSIGKKTHQADDNIMKEAERLLNEEFATILDISPNEVS
                     SYISSHIPQ"
BASE COUNT        31438 a         8434 c        13969 g        26163 t
ORIGIN      
        1 aaaattatct ttatcaaatt tttaatgtta taataaacag tactaaatta atctttaatt
       61 atagctggat atatattttt ttatgcatta ttttttcagt atttcaaggt ttttttccaa
      121 taatatcttt gttaataatg caaaaaatga taaatgcaat tcagatgaaa aatatagggc
      181 aagatatctt tttaaaatta atttttatct atatagtctt agagatgatt gatttaatgg
      241 ctgtagaaat ttataattta tactctacga catttatgaa aaggtttacc agacatatag
      301 agattttaat gttagaaaaa gctaatagat taactacgaa ggattttgaa aataaggaaa
      361 tttatgattt aatcaataga gctcaatctc aaaatggagc tacagttatt gattacttta
      421 actcctggat tttaattttt caacaggcaa tcacaatatt ttcctcgatt attataatta
      481 tatcttatca atattggatt gtaatattaa tcataatagc cccagttata caattttatt
      541 actctcaaaa attagggcat gagcagtatg aaataagtat gaaaagaact tctgaagaaa
      601 gaaaatgttg gtatattaat tttttaatgc tattaggaaa ttcaatcaaa gaaacaattt
      661 tatatggatt aggaaattta tttataaatc agtatggaaa attaaaagaa aaattcattc
      721 ttcaagatta taaaataatg aaaaaaacat ttgagatgaa ttttataatt ataattattg
      781 gtcaattatt tacaggagtt atatattttc atatacttct taatgggttt tggcagaaaa
      841 tatatatggg agatgtaact acttacataa cctgtataac aacaataaaa aatggtatag
      901 aagtgatatt atcaatgatg agtacaatat atagtaaatc tctatatatg gaactattat
      961 ttagattttt tgatattcct gagaagacgg aacttaataa aacaaaactt aaaatagata
     1021 atatagaaaa aatagagcta aaacatttat attataaatt tactgaagat tcaggttatg
     1081 ttctaaagga tattaatcta gaactaaaaa agaatagtcc tattgcactt gttggtagaa
     1141 acggttctgg taaatcaact ttaatcaaaa ttatactagg aatttatgat gattatgaag
     1201 gagatatctt aataaatgga attaacctac ataatatcga aaaagaaaat tactacaata
     1261 aaataagttg tgtttttcaa gactatacca aatatgaagc tagtgtaaaa gaaaatgtag
     1321 gatatggaaa cctagatcag ataaataatg aggatttgat aaaagagtca ttgataaaat
     1381 ctggactaga tattaatcaa ttggggagta ataaattaaa taccatttta ggatattggt
     1441 ttggagaaaa tcaactttca gaaggccaat ggcagaaaat agcaatatca agagctatga
     1501 tgaaagatgc tgatttttac attttagatg aaccagatgc cgctttagat ggaatagctg
     1561 aaaatgatat gcttttaact tataaaaaaa tgtttgaaaa taaatttggt atattcgtat
     1621 ctcataaaac acatcattta aatttgttat gtgaaaatat aatagtttta aataatggac
     1681 aaattgcaga atgtggaaat catgagcaat taatcgaaaa agaaggaatt tatcatcagt
     1741 tatattcaag tcaaattata agtaaactag aaacaaatta ataattactt tgaaaaggag
     1801 ttaagaatta tggaacaaaa accttttatt catttatttc aaacatcaac tgggttctat
     1861 ttttatgatg tgaatactga ttctatatta aatatagatg aaaatgtcta tgattatcta
     1921 aagaaagaac aacttggaga gtcaagtagt aatacattag aatatgtaga atttttaaga
     1981 aagcaaggat acttaaaatc aaataaagtg aaaataacag aacatccaga aactgaagta
     2041 ttaaagtatc attgtgaaaa tagggtagaa ggaataatat tacaagtaac tcaaaattgt
     2101 aacttacatt gtgattattg tacttattct ggaggatata taaatagaat acatacaaac
     2161 aaaagaatgt ctaaagagac tgctaaaaga ggaattgatt atttaataag ccattcaaga
     2221 gattgtcaat atgtgagtat aggtttttat ggcggagagc cattactaga atttgattta
     2281 attaaatggt gtattgaata ttcaaaagcg aatatagaag gtaaaaattt gaaatacaat
     2341 ttaacaacta atgcaactct tataacagaa gaaattatag agttatttga agaaaataat
     2401 gttagtatta tgattagtct agatggtcct gctgaaatac atgataaaaa tagaaagttt
     2461 gcaaataata atgtaggatc ttttagtact ataatgaaaa aactagatat gatatctact
     2521 aagtatccaa attattttaa aaataatgta cattttaatt ctgtattagc aactgataac
     2581 ttctcttgcg ttaataaatt ctttactaaa gaagaattat ttcaaaattc attattttta
     2641 tcttcaattg ttagtgaagt aaatgctaaa gttaaaactg agaaatcaca aagtttttat
     2701 gaagaaagtc agtatgcttt attcatagga tatttaactt tacttggtag aataaaaaaa
     2761 gaggatagtt ctaaattatt acaaactcaa atctctacta ttggagatac gcgaaatggt
     2821 aaacagggca aacaacgttt agtaatgcca gaaaaatggc atcatggggg tccatgtgta
     2881 ccaggagtta tgagattatt cataaatgtt gatggttatt tttatccatg tgaaaaagca
     2941 tcagaagcat cagatagtat gaatatagga aatttagatc aaggatatga ccttaaaaaa
     3001 gtagaaaaat tattgaatat tgaaagaata aatggtgata aatgtcatag ttgttgggct
     3061 tatgaaaact gcagaatttg tgctgtttct ttaagtgttg attcaacaca agaagatata
     3121 gcaaaggagt gtgaatatat tagaagtagt atagaaagtg atttccaaga ttattgcgta
     3181 ttaaaggaat tgggatttga ttttgaaaca aaagaactta tagaaaatac catttaattt
     3241 aagatagcat cttaaattat tacattatga aactaattag aatctattgg aggattaaaa
     3301 tgaaaaaagt attaatttat ccattcacag aggaaatggc tccatttgtt aaacaagaga
     3361 atttactaaa agatatagat ataacatcaa ttgtaagttt aaaggggaat ggaatcttag
     3421 gagataaata taaatttaat ggtaagtctt tagaagtttc tgaaaatttt gataaggaat
     3481 tagaaaaatg tacatatatc ttacttaata atttttatag tgatgaaagc gaaaatatta
     3541 ttttagaaaa tataaaaaaa gctgtaaatc atggtaaaaa aataatcttt tttagtaatt
     3601 caaatagtaa tattgataat ttaaaaatga ttatacctaa agaacaacag tttgaaatta
     3661 atagttcaaa aaatatggta aaagattttc aaggaagaat atacaatatt gatacacctg
     3721 ttatttttgt atgtagcata tttgaaggct tagaaaaatt tgatattcaa ttagcattaa
     3781 gaaataagtt actaattgat ggatataagg ttcttcaaat tggaacacgt caagtttgcg
     3841 aattatttga tttctactca ttccctgagt ttatgtactc aaataatata gaagaacaag
     3901 acaaggtact aatgcttaat aatactctaa aaaaattaga attagaaaaa aaacctgacc
     3961 ttataattat cggaattcca ggtggtatac ttccattttc ttcgaaagca tttggtgatt
     4021 ttggaattac aatgtacaaa gtacttcaag cagtaactcc agactgtaca atactatcta
     4081 ttccatatgg taaatatagt gatgaagaaa tttcttattt tggtaaaatt acaaaaagta
     4141 agtttaatat agaggtagat tattacaata ttgctgcgaa atcaatatta tctcacccaa
     4201 cagagactat gggaaaacca ttttatttaa cattaggaaa atcattagtc gagaaaaaaa
     4261 tagccacatt acagaataaa aatgtatttt gtttatctaa caaatctgaa atagacagat
     4321 taatagaatt aatgatcaaa gaatttataa aatatggtac tgtagcatct atataaaata
     4381 ttttacataa aggatggtga aatactgata tggtaaacac agaagttatg aataaactag
     4441 atatctatac agttttagta aatatatttg agaaaagatc aaaaataaat tttgatgaaa
     4501 attgttattt aaaaaatgaa aatttatttg aatctaagat aatgatgcct gctcgtgaac
     4561 tagtattaac attgtatgat atagaagact atttttctat atctattcca gaggatgtaa
     4621 ttttatcagg aagatttaat tcttttaaca atatttatga tattgttaaa aaacttgaga
     4681 attctattaa ttttaattaa ttaaaatata ataatataac aaatgagagg ggaaaaatga
     4741 tatgtctaat tttggaaaaa gaaatttata tgattctgca aatggagaaa tagatcctaa
     4801 aggaggatgt aattgtggtg ctctgtgtgc aaatctatgc tcttgtagtt gttctggggg
     4861 aacatggtca ttctatcaca caaatcaagt gaaaggttct aaaataaata atggtcaaca
     4921 atttagatca ccaggagaaa tacctggaca aaaaaaataa aaagagttaa atataattag
     4981 ttttagcttt atcaattaac ataattaact ttattaaaat taatagaatc taattacaat
     5041 tgtttattat atctataaaa gcaactttaa aataccttgt tttatatatg ttaattaaaa
     5101 atggtaggag ctgtcgtgct agaaaatagt gctacagctc ctaccatttt tacataaata
     5161 actttattta taatatatca ttatactttc gtaaggtttt atttccattt tattttcaat
     5221 tatatctcta gtgtaattgg tttcaagtat tgtgtagttt aatttattca aataagtttc
     5281 aggtaattta tatactacat tatcatgagt aaaattactt ataacaagaa gattttggtt
     5341 tttatactct ctttcataaa caaatagatt tttatgattt tcatctaaca atctataagt
     5401 accttctgta aaaatatcat attgtttacg atatttgatt aatctttgat aagtataaaa
     5461 gactgaacga gaatcattaa gctcattttc tacactaata ttgtcattat taacttttaa
     5521 ccacggttta tgattagaaa accccttata aatagtatta tcccattgca taggagtacg
     5581 ggcattatct ctggattttt gttgaagtat aagcaatgcc tccttttcat caataccaga
     5641 tttaatcata tgatagtatg aattcttact ttcagcatca tcatattcat ctattttagt
     5701 aaagtaggca tttgtcatac ctatttcttc accttgatat atgtatgtag taccttgtag
     5761 accaaatagt gttatggcta acatcttagc actttcttga cgaaaaaatc tatcatctcc
     5821 aaatcgagat aaagctctag gttggtcgtg attagagtaa aatagagcat tccatccctt
     5881 tccttcatac attttatatt gaaagtcaga ttgtgctttt tttaatttat ccagagagaa
     5941 catttcatta gtccattttg cgcctccttt ataatctgtt ttcatatgat ggaagctaaa
     6001 aaccatagat agttcttctc gattttctct agtatagttg atacactctt caggtgtagt
     6061 agatgacatt tcacctacag taactatatt tttaggtttg aaaacttttt gattcatatt
     6121 atgtaaatat tcgtgtatac gaggaccatc agcgtagtga gttcttccat ctccttttgg
     6181 tcctgttata gggtcatcag gtaatccagg tgttttggag agtaggttga ctacatctaa
     6241 acgaaaacca tcaatacctt tatcagccca aaattctagt attttgtaac attcttcacg
     6301 aaccttttca ttttcccaat ttaaatcagc ttgagtttct tcaaataaat gtaaataata
     6361 ttggttagtg gtttcatcat atttccaagc agttccacta aatctggata tccagttatt
     6421 aggaacagaa ccatcaggtt tagcatcttt ccagaaataa taatcacgat atggattgtc
     6481 tttgcttttt ttagattctt taaaccattt atgttcagta gatgtatggt ttaggaccat
     6541 atccatcatt atttttatgt ctcttttatg agcttctttt aagagttttt caaagtcatt
     6601 cattgtccca tattttgggt ctatattata ataatcttct atatcatatc cattatctct
     6661 ttgaggagaa acgtacatag gagtcaacca taataaatca acacctaaag aatacagata
     6721 atctaatttt tctataatac catttatatc acctatacca tcattgttgc tatctttgaa
     6781 actttttgga tatatttgat agacagttgc ttttttccac caatttttca tacttgatac
     6841 ctcctgtaat ttataagtta attataatat gtttaaacaa attgtcaagt attaaactga
     6901 tattaaagct aaaatataca ataaataatt atttgtataa acatataatt gtatatagaa
     6961 tagtgaggtt agtatgggat aaagtgtcta aacgtaaaaa aattatgttt aattaaacat
     7021 aattttttta atatctttga gtaacatcca tgaatacaaa tgtttcaggt gtatgctttg
     7081 attcagtata ttcaaaaagc tttccatcat cagtatatac actattttta ataacaccaa
     7141 cacaattata atcatttaga ggtagcgttt ttaactcaag ctctgtagct ttttcaattt
     7201 taaatatctt tctggatgaa acaatttttg tacctagaca ctcttctata tatttataaa
     7261 tagagccttg tgctatagaa acatcaaggt ctttaactat actacataga aaatagttaa
     7321 tgtcgagaat tttaggtatg ttatcaatat atcttagtct gtgaaggtaa tatacttcac
     7381 taccaacttt aaaacctgtc tttttagata acttattatc aattaagatt ttgctgaagt
     7441 ggagaacact agtagcagta ttaacctttt tatcttctac aatcgattct acacctttga
     7501 aattgtgcat atttagaaaa aaatcattag aacaactatt ttctaacact acaacacctt
     7561 tgccttttat actttgaaca tatccttctg tgtttaattg agaaattgct ctacgtacag
     7621 tgtttctgct acatgaaaac ctttcaataa gttgaagttc agtaggcagc atcatattac
     7681 ttgtatattt accatcaagt atttcctctt tcaatacttc atatatctct gaaaatttat
     7741 ttttagccat atacccctat ccctccttaa aggtctttag taatcttatt gaactgatat
     7801 gaacaaatta tatcaaatgt gtttagacat gtatagtgaa aatagaatca tatcaaccat
     7861 aaaaaggaca aaatagaatt attttgtggg ttgtttcaaa tacatggtta aacatatttt
     7921 taaaataaaa aaaatgaatt aaaaaaatag gctagatata gcaatacact taaaaggatt
     7981 tatatgttaa accaaatgat aaaaataaaa tgaataaaaa atattgacaa tttgtttaaa
     8041 caaatataat atttaaaata taaaatgtga ataaatcgtt ttcataaaaa attaaaccga
     8101 aatagaaagg ggattgtata tgaagaggtt cttaaacaaa atgatgcaac aactgtcact
     8161 tttaggaaag actatgctgg tgccaatagc tgtaatgcca gcagcaggta tattaggatt
     8221 attatttggt ccaaatatgc tcaatgtgcc agctatatct aatatatcta atatagtatt
     8281 ttcaaatgtg gactacttat ttttattagg agcagctagt gcctactcaa agtctaaaga
     8341 caagacaagt gtaatggttg cagccgtagt tgcatatatg atatttaagt caaatttaga
     8401 gttattgaat gatacattaa atgcaggtgt atttggtggg ataattgttg gagcttgtat
     8461 agcatggact tacaataaaa catataaagt taaagttcca gcatttttaa gcttctttgc
     8521 aggagaaaaa tgtgtaatta cactatcacc agtggttgct ttaattttat catatatatt
     8581 tagtttatta tggatatatc cacaagctgc aatgaatcaa tttggttttt ggttgggagg
     8641 agctggtgca ataggaatat tcttgttttt attctgtaac cgtgcactaa taccaactgg
     8701 gttacatcaa gttttaaatg cttacatatt atttgaaatg ggtgaatata caacatcaac
     8761 aggagaagtt ataagaggag aaattcctag atttatggca ggagacccaa atgcaggatt
     8821 cttctggaca ggattttaca taattatgat gttttcaata cctgctattt cttatgctat
     8881 atataaaaca gcacaagata aaaagaagca agaagtaaaa ggtgcaatga ccgctggagc
     8941 attgacttct tttatggcaa cagtaactga accaatagaa ttttcgtttt tatttgcatc
     9001 tccaaagtta tatataattc attcttttta ttctggtcta ggtggagttg tactatattt
     9061 actgggtgct cgcttgggtt catttaatgg agcaagtata attgactatg tcttaagttt
     9121 tagttatgga gataaagcgt ggttagttat acctgtagga gttgtattct ttgtattata
     9181 ttatgtaaca tttaaatata taataataaa agataatgtg caaacaccag gacgtgaagt
     9241 tgagatagag ataggtgata aagttagtga aaaagaaaag aatttaaaac tttctcatgg
     9301 taatttttca tatatggcta aacagataat taaaaattgt ggtggttatg aaaatatagt
     9361 gactcttaat aattgtatga cgagattacg tttagaagtg aaggatgcta ctattttgaa
     9421 tgatgataat attaaaaaaa caggagccaa aggggtaatt aaattgagta atacatcagt
     9481 tcaaatcatc ataggaacgg atgttgttaa agtaaaggat gagatggaaa tgcaacttga
     9541 tgagttgaga aagcaggcag atgcataaaa tgaagaaatt agtagttagg gcagatgata
     9601 taggatattc agaaggtgtt acactaggga taatatcttc ttataagaac ggtattgtta
     9661 caagtgctgg aatcatggtg aatatgcctt tttcaagaca agctatagaa atggtaaaaa
     9721 atgatgatgt atgttttggt ttacatgtta atttagtaat aggagaacct tgttgcaaag
     9781 aacatattaa gataaagaat ttgttagatg aaggtggaaa atttgtttct agcaaaataa
     9841 gaagaacgca actactgaca ggtaaagagg tttttaatta tgaagaagta tatgaagaag
     9901 tttgtgctca aattgaaact tacaagttgt atatgagtaa attgcctgag tatattgata
     9961 tacatggtat agaagaagat gtatcaatat cagcaatgtg tgatgctgca aaagaatacg
    10021 gtataccaag ttgtccctat tatttagatt cgtgtattag catgccaagt aaatatcctc
    10081 agaatgattt ttacaagtta aataaatctt ttgttaaatt atttgaagaa aaatatataa
    10141 atttagataa agatataaca ttgatggtta ctcatccagg atttatagat tatagtctta
    10201 taaaatcatc ttctcttatt caagagagag tatatgaaca tgcaatgcta tgtgataagg
    10261 aagttaaaat gtggttaaaa agaaataata ttgaattggt tgattttaaa gatattttca
    10321 agtctaataa ttatatataa agaatagatt acctaaagtt ttaattaaaa ataagtattt
    10381 gaaaaaaatg tgtattttct aaaaaaatat tgatagagat gtatcaaaat aaaaacttga
    10441 atcatctcta tcaatatagg aagtacacat tttttatgta taataaaaag agtagtatgc
    10501 attaataaat taaaaatatt aaattataat tatattaacg aaaattttag ctaatatttt
    10561 tgaattttac ttatgaataa taaaatagat ggaggagaaa ctatggaatt ttatgaaaga
    10621 gcaaaaaaat atgagtataa atttacagat acagaagaca tgataattga atatatgaga
    10681 aaaaacaaag aagaaatagt aaaattatca atacaatctt tagcagataa attttttact
    10741 gtcccaaata ccatagttag gctatgtaaa aaaatggagt atgatggttt ctctcaacta
    10801 aaaaataatt taaaagaaga gttaaaaaat gagaataaag agccaaaaaa tggttttgaa
    10861 tcagatataa aaaagacatt agagctaata gattatgaaa aaataaataa agtagcagat
    10921 ataattcaaa aatctaggag tattatagtt tatggaatag gtcaaaacat tcctttatgt
    10981 gagatattag taaaagaaat tagaggtggg catgataata taacttacta tagtcaaaga
    11041 catgaagtac ttcatgatat aggaaaatta ggtgaacaag atatgttttt tgcacttagt
    11101 ttaagtggag aaacgaaaga agttatagaa gcagcaaaga cagcagttaa taagggttgt
    11161 aaggtagtag ctctaacaca tatatgtgaa aatcaattgc aacaaattgc agatataagt
    11221 ttatattgct attcaacaat taaacaagta aatgggtaca atatatcaga taaggttcca
    11281 attatgatga ttatgagagc aataatagaa caatactggt taagatagag atttgtgtat
    11341 aaatacacaa atctttattt tttaagaaga aattgtgtgt ataatttcaa aaaaacattt
    11401 tcataattta ttttatgcta tattcatagc attaaatgat ttaaggaggg cgtaattttg
    11461 gaatttaaga aaatcacaaa tgaaaacctt gtttttttaa aacaaaaaat aaaaacaaag
    11521 aaagacgcaa taaagttctt agcaagaaag ctatatgatg aaggcaagtt aacatcttat
    11581 gaggaatatt tagaagctgt aatgtacaga gaaactttat ctccaacagg ttttgaaaga
    11641 gggcttgcaa ttcctcatgg aaaatctaag tcagttaaag aagctgcatt tgcagctatg
    11701 accttagaga caccaataga aaattgggaa agcgtagacc caaataataa agtagagata
    11761 atatttttaa tagcagtacc agaaaatgaa ggtggaaata cacacataca aatactttct
    11821 gagttagtta ctagactgtc aaatgaagat tatatgaata tgttgttaaa ttcaaaaact
    11881 aagaaagagt tatttaataa cttagatata aaagaaaaga aagaacaaat aaaagaagag
    11941 attaggattc aaaatgaatc aaaaaaaatt atattagcaa taacagcatg ccctgcaggt
    12001 atagcacata catatatgtc agcagaagca ttaattaaag ctggtaaaga aatcggtgtg
    12061 gatgtgtatg tagaaaagca aggagctaat ggtatggtgg accctcatac accagatata
    12121 ataaaaaggg cagatgcaat aatatatgca acagatgtag cacctaaaaa tacagaaaga
    12181 tttgaacatt tgccaaacat aaaaacgtca gtagcagctc cactaaaaag agcaaaagaa
    12241 ataatatacg aagctttaga agtagcacaa aaacaaggta aaggtgatta tatagaaaaa
    12301 tcatctgata tatcatattg tgaaaaatca tcatggaaaa aagatgtaaa atcagcaata
    12361 cttacaggag tatctcatat aataccactt attgtggcag gaggtatgat acttgcattt
    12421 gcagtattag catctcaagc atttggtcta caagaactat acaaccaaga aggttcttgg
    12481 ttatggcaat taagaaagct ttctggaggt atgttaggta cattgatggt tccagtatta
    12541 tcagcatata tgtcttactc actagctgaa aaaccaggtc ttggaccagg atttgcagca
    12601 ggtctagcag ctgatttaat aggtagtgga tttcttggag gtatgttagg aggtttactt
    12661 gctggttata tagtaaaatt tttaaagaag aatataccag ccaaaggcac attagctgga
    12721 ttcgtaagtt tttgggtata tccagtagtt ggttctttgg tagtaggttt attgatgtta
    12781 tttgtagtag gaaagcctgt agcagcactt aacaatggtc ttataaattg gttaaatggg
    12841 atgactggag taaatgcaat actactaggt gcaataatag gagctatggt ttcatttgac
    12901 ttaggtggac caataaataa agcagcctat acatttgcaa taggagcaat agcaagtgga
    12961 aattttatac cttatgcaat atttgcatca gttaagatgg tttcagcttt tggagttaca
    13021 atagctactg ttttaggcag agatttattt tcagaatcag aaaaggaaat aggaaagcaa
    13081 acttggatat taggattggc tggaataact gaaggtgcaa taccatttat gatagaggac
    13141 ccaatccgtg ttataccatc attggtagct ggttcagcca taactgggtc tatagtagca
    13201 ttcttcaata taggtcttca agtgcctgga gcggggatat tctcattggc gcttttagag
    13261 ggaagtatgt caggatttat tatagcatca atatggttct ttgcggcagt acttggagct
    13321 ataatatcag caatattatt aataataact aggaaacaaa aaaatcaaag aaagatacat
    13381 aaaaagatac gttattagat atttaaatca aaggtttaat tatagtgata aaataaatat
    13441 taaaaaattt tgtaaactca gtagtatttt tattggattt ttaattagac agaaaatatt
    13501 atcagataag ttttggagga taagcaatga aaaaaaatgt acacatagtt cctcatatgc
    13561 attgggatag agaatggtac ttctcaactg aggaatctag aatattactt gtaaataata
    13621 tggaagaaat aatggatatg ttagaaaata atcataacta tccatattat gtgatggatg
    13681 gtcaaactgc tatattagaa gattatttag cagttaagcc tgaatgtaag gagagaataa
    13741 aaaaattagt tcaagaagga aggctaataa taggtccttg gtatactcaa actgatgaaa
    13801 tggtagttgg tggagaatcc atacttagaa atttactata tggaataaaa gattgtgatg
    13861 aatttggaga atatatgaaa ataggatatt taccagattc atttggtcaa agtgctcaaa
    13921 tgccacaaat actaaatggg tttgatataa aatactcaat gttttggaga ggatgttctg
    13981 aaagaaaagg aactaataaa acagagttta attggaagag tgatgatggg tcttctgttt
    14041 tggttcaaat acttccatta ggttatgcaa taggaaaata tctaccaatg aatgaagatg
    14101 agctaagaac aagaatggat aaatatttac cggttcttga taagggtgca actactgacc
    14161 atataatact tccaaatgga catgaccaga tgccaattca aaagaatata tttgaagtta
    14221 tatataaatt aaaagaatgt tatccagaga gaaaattttt cttaagtaga tatgaaaaca
    14281 tatttaaaga gctagaaaaa aatgaggata tagatacaat aaaaggggaa tttttagatg
    14341 ggaaatatat gagggttcat agaagtatat tctcaacaag aatggatata aaatcagcaa
    14401 atgctagaat agaatcaaag ataaccaaca tattggagcc actagcttct attgcatatt
    14461 ctctaggatt tgaatatcat catggattaa tagagttaat ttggaaagaa ataatgaaaa
    14521 atcatgctca tgacagcatt ggatgttgtt gttcagataa agttcaccat gaaataatga
    14581 atagattttt cttagctgag gaaaaagtag accaattaat aacattttac aaaagaagaa
    14641 tagttgatgc aatgagttgt gaaatggctt tagataagtt agtagcattt aacttaatgc
    14701 cttacgatag gaatgaaata gtgaacgccc aagttataac taaaatgaaa gcatttgaaa
    14761 tatttgataa agataataat aagttggatt ttgaagtggt acataaagaa gtaatagatg
    14821 caggattaat agaccgtcaa attgttcatt atggaaacta tgattcattt atggtatata
    14881 caataaactt taaagataaa atacctgcaa tggggtataa ggcgtatatg ataaaagaaa
    14941 ttggacatat gttagaaaaa gcttatgaag tatgtgacat ggtagataat gacttttata
    15001 ctattcaagt taatgaaaac gggacattaa agatatttga taaaaaatta aataaaactt
    15061 ttgaaaatgt attattgatg gaaaatggag gagatgaagg agatgagtat gatttttcac
    15121 cacttccaaa tgagaaatta atatttaacg ataatatagt agcaaattcc actataaaga
    15181 aaaatagatt taataatgag ataaagataa attatagatt aaaagtacca aaagatatac
    15241 aagctagaaa aaataataga gcagattcat ttattgactt tgatatagtt ataaatgttc
    15301 caaatgataa agctataata gatgtagtat tcaacataaa taaccaagca agagattgta
    15361 gggttagaac ttatatacca acaaatatag cttcaaagtt ttctgtgtct gataatcagt
    15421 ttggacatat aaagagaagt gtgtatgatg atgctatgga agtttggcaa caggaagaat
    15481 ggagtgaaag accagattct atatatccaa tgctaacatt cgttggattg tctgacaaag
    15541 agcatggagt agctgttctt acaaacagta caagagagtt tgaaatagta ggggaaaaat
    15601 ttgacacaat agctataaca ttatttagaa gtgtaggatt cctaggtaaa gaagaaatgg
    15661 caagacgccc aggtcgtcca tcaggaataa agttgcctac tccagattct caaatgatag
    15721 gagatataaa aatagactta gcaatagtta ctcatgaaaa atctacacta gaagcaaatg
    15781 ttgcaaatat ggctaaagag tatttaacaa aaatacaaac ttataataaa atgccatata
    15841 atgctatgaa attgaatcaa tcagaaatag aagtagatta ttcatatagt ttacttaagg
    15901 aaactaataa ggaccttgtg ttaagtgttg taaaaaaggc tgaaaaacaa gaggcattag
    15961 tagttagatt ttacaattct aaagaagaaa caaaatcagc taacatagta tttaacaaaa
    16021 atattaaaac agctaaatgg attaacctaa atgaaaaaga attagaatct atatcaatag
    16081 ataataactt tgtaaatgta gagtgcttaa tgaaccaagt taaaactata ttggttaaat
    16141 agtgctaaaa aggaattgtc ttaaaataga gataatcctc cttatcattg ttgaaataat
    16201 aaacatatat ttgattttat acaaaaagag tgtctcatga actaagaaat ttattttgag
    16261 acactccctt tttataagat aaaagaatat taatggtata agttgtatac aaagagagat
    16321 gtagagtata aaataaaaga taaattaagc ttataaaatt atatgtttaa aataaggagt
    16381 aataaaaagg agtagataag tatgaaaata ttaatttcta tagattcttt gaaaggaagc
    16441 ttatcttcaa tagaggcagg aaatgcaata aaaaagggga tattgaaggt taaagaagat
    16501 gcgcaagtaa agatattgcc acttgctgat ggtggtgaag ggacagtaga tgctttagtt
    16561 caagggatga atggtaaaaa agagactata gaagttactg gaccaatagc taaaaaagtg
    16621 gatgcaacat atggattatt aaaaaataca agtacagcaa taatagaaat agctcaagca
    16681 tcaggactaa cattggttcc gactgaactt agaaatcctt tatacactac aacttatggt
    16741 gttggggaaa taataaaaga agcaataaat aaaggctata gaaattttat agttgggata
    16801 ggtggaagtg ctactaatga tgctgggata ggtatgcttc aagccttagg gtttgagttt
    16861 tatgatgaaa ataacaagtt agtaggatta ggtggaaaag ttttaaatga aataagacat
    16921 ataaaaatag aaaatagatt aaaggaatta gatgaatgta agtttaaaat agcctgtgat
    16981 gtaaataatc cgctgtttgg gaaaaatgga gctgcataca tatacgggtc tcaaaaaggt
    17041 gcaacatcag aaataattga ggagttagat aatgggctta gaaatttttc caaagtagtt
    17101 aaaagttact taagtaaaga tgtagctaat gtagaaggag caggagcagc aggaggatta
    17161 ggttttgctt ttttagcatt tttaaattca aaattagaat ctggaataaa aataatatta
    17221 gaagaaatta aattagagga agagttaaaa gatgcagatt ttgtcataac tggtgaaggt
    17281 agattggaca atcaaactgc tatgggcaag gctccaatag gagttgcaaa actggcaaaa
    17341 aaatatgggg taaaagtaat aggtttggct ggagccacaa cagaagatgc agttaaatgt
    17401 aatgaagagg gtatagatgc ttatttttct atagtaaata gagctatgac aatagaagaa
    17461 gcaatggata aagcaactgc tagtgagaat atgacatcta caacaacaca aatattcaat
    17521 cttataacta gtatacaaca gtcaaaaaat atgtagtatt aaaacaaggt atattaggta
    17581 aaaagctgtc acatattaat ttagactttt tagtgtgaca gcttatctat tttatgttaa
    17641 taacttaaga aacatatatt ggaaataaat taacggattt agatattttg aataagataa
    17701 gctattctat tcataaaact actatagtta tctgccttag taagttcttt aacattattc
    17761 cactcagata atatttcaat aaagctttca aatatgtaat tgaatttttc tttttctttt
    17821 tcatttatag gtatcatagc tataatctga actttttcct caccccattt aactggttta
    17881 tcgttaacaa ttaaacatac tccagttttt aaagcatcca ttttcatgct atgaggaatt
    17941 gctacattgt tattaaatgc agttgaagac attttttctc ttataagaac atcatctata
    18001 taattgggtt tgacatattt attttcgtac agaatatttc ccataaattt tatataatct
    18061 ttagcactat ctaaatatat atttttcata aacaaagatt cactaaagta catttctaaa
    18121 tgattttgta cagtaagtat atttttttta tctttaatct gaataaattt actttggata
    18181 ttatcataat cctttctatt taggtaagga tttacataaa caaaaggtat agggcatcta
    18241 tcgttaattg gtaaagtagt aataaccatg tctaccttat tgtcaaaatc aagattatga
    18301 gtatctgaaa aaatctgaat aatttctatg gattcattaa atctcttctc gaggtctctt
    18361 actattttga attgtaaatc atagtaattt ggagtaatta atgcacatag aactttatct
    18421 tctaataatt tttgtctatc aaagaatgaa cctacatgaa gagatatata agatatttca
    18481 tcttcgtcta tatctacatt ttctaaagtt tgaatctgat tgcaaatata aacagatata
    18541 tcatatatca aagggtagga atcttttaac ttttgaggta tttgatttct taaaacttga
    18601 ttatttttgg ctctactgat taaatttttt acatgaagag taaattttac aacaaattcc
    18661 tcatcagata aatctataag atataagtca tatacatttt taattatttt tttagttaat
    18721 ttaacaaagt gatcatctat ataatttggc aatgacttag tatccatttc atgataattt
    18781 aagactgtgg ttttgtttgt taactgaaat actaagtagt ataattctgc actagttaaa
    18841 gttatattgt attcagactc taaaaaattt gatatatctc ttgaaatgct tatatcatta
    18901 ttattatcta tgtagtttac tacttcgaca gattctatgt agttattctt ttttattctg
    18961 tctatagtta tcattaaatg aagaagtatg ttatttatag catactcatt tataaacaaa
    19021 ttgtattttt ttaatatata tattatattt tctttcagtt tggtcaaatt atactcttga
    19081 tatatttttt gtacatcaaa taagcttaaa aaatcacttc ccgtttcttt aaatattata
    19141 gagctcatta atttgcgctt tgcagactca tttccaatta gtttcaataa aaatttcgat
    19201 tgctttatct ttaaattata acttcctata aatttattag ctttgactat atccccttca
    19261 atagtagctg ggctaacaaa caattcttca cttaaatcaa atatattaat tccattacta
    19321 ttaactataa gttcttttaa aattaaattt aacctgttat caggtgatat attttctgaa
    19381 ctatcaacct tggtttgaca attattattg agatttactt tatatccttt tttagaggat
    19441 aatataaatt caccattgga attaatttcg tttacatatt ttctaattga acgcgttgag
    19501 acattaagat aattagccaa tgtagatgaa tctatccaat catgttgtgt ttttatgaaa
    19561 tttaaaaata gttctttttt agatgttttc attagattcc ctcgcatagt tttaaaataa
    19621 aatctggatg atatgataat tatataattg aatgtacgta ttataagata cattatacta
    19681 tattaatatg tttaattaag agtaactgat ttcctattat taggaaatat atttatgtga
    19741 aatgaactta tttggtaagt acaatataaa cataataaaa taaaaagttc attaagaaat
    19801 aaattaatgg ataaaaatat tggaggtatt attatgaaaa atataagagt gcttttggcg
    19861 tgtggttcag gagcaagtac aggttttatg gcaactagta tgagaaagag tgcaaagaaa
    19921 aaaggtatag aagcagatat aaaagcgaga agtgagtcag agatagataa gtatttatca
    19981 gaaatagatt gtttattact aggaccacat ttagattata tgaaggaaga aattcaacaa
    20041 aaggctaatg aatataacgt tccagtagca tgtatatcta aaactgcata tggaagacta
    20101 gatggtgcaa aggctttgga agaagcacta gaactaatat caaacaaata aaatatttat
    20161 ggggagagtg tttatgaata aatttataga ttttttaagt gaaaaattta ctcctgttgt
    20221 aaataatatg actaagaata tatgggtaca atcagttcaa tcaactataa tgaaagtttt
    20281 gccaatggta tttgtaggct cattagtaac tatagtttct gtcttgaaga attacataag
    20341 ctttttacct gatttaagtc caataaatca atatacattt ggacttttag gattatttat
    20401 agcattttta ttgcctatgg aaataatgaa gaataagaaa tttgaaagta tgagtgtagt
    20461 cgctggtctt gcaggtgctg gattaatgtt aatgatgatt cgtccagaga ttacgaatga
    20521 aggagctata tttaacttca acaggtttgg aggagaagga atgcttgtat cgctagttgc
    20581 aggattattc tctggattaa taatgtcctt atttggttct ttttcatttt tcggagaaga
    20641 ttcagcactt ccggattttg taagcaagtg gtttgataat atgttaccta taacagtgat
    20701 aatgtttgta ggctggggat taatttatgg actcaacttt gacatgtttg aaataatagt
    20761 tagagtattt aaaccagtat cagatatagc acagacatta cctggatttg tactcttaaa
    20821 ctttttagta gtatttatat attctttagg aataagtggg tgggtactat cccctataac
    20881 ttattcaatt caacttggtg caattgcagc taatgcagca gcagtagcat caggaggagt
    20941 agcaactaat atatatgttt acgaagttat tcaaacaggt tggataactt taggagggtt
    21001 gggtgctaca ttaccattag ttataatgat gtgtttatcc agagttggaa gaataaaagc
    21061 aataggaaga gcatgtattg tcccttctat aatgaatata aatgaaccag taatatttgg
    21121 agctccagtg gcatggaacc catttttaat gttacctatg tggataggta caatagtaat
    21181 atcaataact acttatttat caatgagtat gggatttgtt acaattccaa gtaaggtgtt
    21241 taatttatgg tatgttcctt ttggtatatc tacttttatg gtaaatcaag atgttagagg
    21301 tcttattgtt ttagcaataa atatagtatt gctatttatg atatggtatc cattttttaa
    21361 agcttatgag aaagaagaga taaaattaga gagccaagag gtttaaattt agaaattgaa
    21421 aggaaattat aaatatgaca attgaagaac atataataga tgaagaatta gtagaggtgg
    21481 caatgcaaat aatacttcgt gcaggtgagg ctagaacaga aattaaacat gctcttaatg
    21541 atttggaaaa gtttgattat agaaatgctg atttaaaact agctaaagca aaagggttta
    21601 tgacagaagc acatagagct caaaccaaga ttatacaagg ggaagctgat ggagagaaaa
    21661 gagcacattc gctgttattt gcacatgctc aagatactct tatgaccata ttcagcgagt
    21721 taaatataac tatgtcttta gtaggaatag taaagtctat agaatataag gtaaataata
    21781 gtaaatgatt taaataaata aaataaggag tgattaaatt gggtaagttt cctaaaggtt
    21841 ttttatgggg aggagctgta gcagctaatc aattagaagg tgcatggaat gaaggtggca
    21901 aaggttggtg tttagctgat gtacatatgt atgataaaga tagagatata tctaaacctt
    21961 atgagtctga tatgactata gaaagaataa agtttgctat gaaagataat aatggatatt
    22021 atcctaagcg tagtggaata gacttttatc atacatacaa agaagattta aagcttttga
    22081 aagagctagg gttaaagtgt tttagatttt caataaattg ggctagaata tttccaaatg
    22141 gagatgattt agagcctaat gaagagggat taaagtttta tgataatctt ataaatgaag
    22201 taatagataa tggtatggaa cctattgtaa cactacttca ctatgagact cctttgaatt
    22261 tagtattaaa atataaagga tggtctaata gaaaagtggt agatttcttt gttagatatg
    22321 cagaattaat actaaataga tataaaaata aagttaaata ttggatagtt ataaatcaaa
    22381 taaatttaat acattatgaa tcatttaatt cagttgcatt ttgtgtagac caggtagatg
    22441 atgtagaaga ggccaaatat caagctattc atcatcaatt catggctaca gctttaacta
    22501 agaagcttgg aaaagaaata aattcagata tgatgatagg gatgatgatg gcagattgta
    22561 catcttatcc agaagattgc gaccctgaaa atgtggtgtt tgctttaaaa agaaatagaa
    22621 tacaatattt tttcactgat gtaagtttta ggggagagta tccagtctat attaagagat
    22681 ttttcaaaga aaataacata aatatagtta tagaggaagg agatgataaa atcttaaaag
    22741 aaaatactat ggattttcta gctttatcat actattattc tacaacagta tcagcaagta
    22801 aaaacaccat gaatccaact gataatataa agaatccata tttaaaagca aatccttggg
    22861 ggtgggcaat tgacccaaaa ggattataca atactttatc tcaatattat gatagatacc
    22921 aaaagccaat aatgatagct gaaaatggat ttggaatgca tgataaattt gaagatggaa
    22981 aagttcatga tagttacaga atagattatt taggaaaaca tatagaacaa ataggtgaag
    23041 ctatagctga tggaaccgaa atattagctt attgtatgtg gtcgccaata gatatagtaa
    23101 gttgttcatc tcaagaaatg gaaaaaagat atggatttat atatgtggat atagataaca
    23161 atggaaatgg aagtaaagaa cgttataaaa aagatagttt ttattggtat caaaatgtaa
    23221 taagaactaa tggagaagaa ttaagagaaa agtaaatagt ttttaaatat aaacaacccc
    23281 ccttataaat actgtatata ttattaatat agttttataa ggggggttat aattgtaaat
    23341 aaaatgattt attaattata tgattcatag cgaaatttat atttatactt ttaatcataa
    23401 acatatcagt atgaggaata tctattgtac ttcatccaaa ttttggtaga ggtacaattc
    23461 ttttttattt taaaatgcta taagataaca taataaactt taagcaaaaa attattatat
    23521 tataaattta catatataga cattgactaa atcttaattg tatataaaaa taagtagtta
    23581 agaggtaata tattatatta ctcgataaat ttagacaaat aaaacttata taaggggaga
    23641 taacatatga taattgagct aaacaaaagt aattctgaaa atctaacgaa gacggaactt
    23701 gaaataatta aatttataaa tgaaaatgaa tcaatattac cagaattatc tatagtagag
    23761 attgctcatg aaacatattc atctccagca accgtttcaa gagcaattag aaaatgcggt
    23821 ttaaatggat tcaatgaact taggtataga ttaacagtaa aagatgaaaa tgatgatata
    23881 caaaatatgg gggatataat aaataaatcc tttatagaag cacagagagt tatagaacaa
    23941 atatctttaa ctacactaat caatataata aaaactataa ataaatctag taagatatat
    24001 attttagcaa gagggcttac tgaatatgta gcaaaagagt ttagtcttaa attgcaatta
    24061 cttgatttta atgttgtttt tataaatgac cccaacataa tgaaaataaa atctaaatca
    24121 ataaaaaaag atgaacttat aattatattt tcattgaatg gaaataccat agagcttgta
    24181 gaatcagcac agaatgccaa tttagttgga gctaaggtta taacttgctg ttgtagtgaa
    24241 agtgcaaaac ttataaagta ttcggattta tatattgtag gatacaaaca tgaacatata
    24301 tcaatttctg aatatgaagt atcttccaga ttgcccttgt atattatatc taggataatt
    24361 atagattata tggtcagata taataattct gaaaattaaa ttgaaaagtc tatgaaaatc
    24421 gattttctat ttgtgaaaag attttcatag acttttttat tataatgaaa acatacacag
    24481 cacaagcaag ggggaagaca atgatatata cattaactac aaatcctgca atagatatga
    24541 atatatctac taatgggata aagagaaaat tagtaaatcg tacatcaaat gctgtatatt
    24601 ctcctaatgg aaagggatta aatgtaactt ttgtactagg tcattatggt atagaatcta
    24661 agatattagg attttttgga ggattttcag gaaaatatat agttgaagaa agcgaaaaga
    24721 gaggatttga cgtattgcct acttgggtag aagatacaac tcgtataaat atatttttaa
    24781 atgatggaag tgatgaattt aaatttgtaa actctgggtc atatgtaaat gaaaaacaaa
    24841 aactagatat gctagataag atacagtcat tagcagatat aagttactta tcaataagtg
    24901 gaagtctacc tcctggtatt gatgataatt actatgagga tatatttaaa atttgtaaaa
    24961 ataaaagtat aaagacaata ctcgatataa gttcaccaaa attaaaggag ttactacagt
    25021 ataatccata tttgataaaa ccaaatgatg aagaaatcaa agatatattt ggaattattg
    25081 taagagatga agaagatatt aaggatgtac ttaaattact acatttaaaa ggtgctcaaa
    25141 atatattgct aactttagga gaaaaaggtt cttattttta taatggaaaa tcaatttatt
    25201 atgctagtgc tcaaccagtt acagtagtca gctctgcatg tgctggtgat tctgcattag
    25261 ctgctttttt aagtatatgg ttggaaaatc cagaacatat tgaagaagca ttaaaaaggt
    25321 cagcagcaac aggagcaagt gtggctgaaa gtaatggtat aggtaatttg gagaatgtgg
    25381 aagattatat aaaaaatata agagtcagaa aggtggtata aaaatgggaa agaaaatgat
    25441 tctaggggta acaggttgtc caactggaat agctcatact tttatggcag aagaagcatt
    25501 aaaaaattca gccagggaat tagggtgtga cataaaagtt gaaacgaatg gagctatagg
    25561 tgtagaaaat aagttaacag caaaagatat cgaaatggca gatgcaataa tagttgcttg
    25621 tgataaaaat gttgatatgg acagattcaa tggaaagcca gtaatagaag tacctgtcaa
    25681 agaaggtata cataaagcta atgaacttat acaaagatgt attgatggaa aagtagctat
    25741 tagaaaagga aacttatcaa gcagtaaaat tgcagaagaa ggaaacttat cgtttggtca
    25801 aaagttgtat aaagacttaa tgaatggtgt atctcacatg ttacctttag tagtagcagg
    25861 tggagtactt actgctatat catttttatg ggggatttat tcatttgacc caaattcaga
    25921 acaatataat caaatagcag ctacattaaa atctgttggt ggatattcta tgaacttgat
    25981 ggttcctgta ttggcagcat ttatagctca atctatatcg ggaagagctg gtatgttggc
    26041 aggacttgtt ggaggaatga tatcatttga tacaggttcg gggtttttag gtggaatcat
    26101 atcaggattt ttagcaggtt acttagttaa actatttgta catttgttaa gaaaattacc
    26161 acgacaatta gaaggtctta aatcgatttt tataattcct attgtcagcg taggtcttgt
    26221 gggtgtagca atgttgttac ttggtgggcc atgttcagca cttaacaatg ctatgatgaa
    26281 ctttctatcg gggttacaaa attcaagccc tataattttg ggaatagtaa taggatgtat
    26341 gtcagcattt gatatgggag gtccagtaaa taaagcagca tatgtaactg gaactatgct
    26401 tctaggacag ggaaattatt tatttatggc aggtgtatct gcagcttgta taacaccacc
    26461 attggtaata gcaatagcat ctactttatt taaaaataga tttacagaag aagatagagc
    26521 agcaggatta atcaattata tactaggtag tactcatata acagaggggg caataccttt
    26581 tgcagcaaaa aatccattaa aagtgttgcc agtacttatg attgcatcat caatatcatc
    26641 aattttaact tatataatga aaatagaagt accagctcca catggagggt ttttggttct
    26701 aggattagtc aataagccac ttttatgggt agggtgtata tttgtaggtt cattagtagg
    26761 tgctgtactt tatatgatgg ttacacctaa agtagtaaat gagaaaaata ctatagaaaa
    26821 tacaaatgca acaaaagatg aacataaaaa tgaaagtgca gaatcggaaa acgtatctaa
    26881 taatatctct ttatatagcg aagaaacagt aattttagat gttaagggaa aaaataaaac
    26941 agatgtaatt gatgaaatga ttggaatact tgataaatct ggtgttcttt tagataaaaa
    27001 gaagtttaaa gaagaaatcc ttaaaagaga agaaatatca tctacaggtt ttggtatggg
    27061 gatagcgata ccacatgcaa aaacagatgc agtaaaggta ccacgtgtag cagtaggtgt
    27121 atcaaaagaa gggtttgact ttgaatcaga agatggaagc ttggcacata ttatatttat
    27181 gatagcagct acagataatg gtgataattt acacttaaaa acattatctc aactatcttc
    27241 aaaattaatg aatgaagaat ttttaaatga gttattaaat agcaaaacaa gtagagaaat
    27301 agtatcaaaa ttaaataacg aagaaattaa atcagtataa acatatagga ggagaaatta
    27361 tggcattagt gacaactaaa caaatattat tagatgcaca agaagggcat tatgcagtag
    27421 gtgcatttaa tgttgaaaat atggagatgg ttatggcagt aatagaggct gctgaagaac
    27481 ttaaatcacc agtaatattg caaacaacac cttcaacaat aaagtatgca ggactagatt
    27541 attatttagc gaatgtaaag gtagcatcag agaaggcaag tgttcctgtg gcaatgcact
    27601 tagaccatgg ttcaagcttt ggactagcta tgcaggcact tagagttgga tatacttcta
    27661 ttatgattga tggttctcat gaaagttatg aagataatat ttcaatatct aaatctgttg
    27721 tagatgcatg tatgccttca gatatacctg ttgaagctga attaggtaaa gttggaggta
    27781 aggaagacga tttagatggt ggtgatgggg gagcatatac agacccatta gaagcaaaag
    27841 agtttgtaga gagaacaggg gtatcatctt tagcagtagc aataggtacg gcacatggat
    27901 tatataaggg agagccaaag cttgatttag atagattatc tgaaattaga gatgttgtat
    27961 cagttccatt agtattacat ggtgggtctg gaataccaga tgaagttatt aaggaatcta
    28021 taaaaagagg gatttgcaag gttaattatg caactgaatt aaggattgct tatagcaatg
    28081 gagttaagaa tgtgcttaat tctgacccag aggtaattga ccctaagaaa tatggtaaaa
    28141 aaggtttaga gtcagttaaa gattttgtta agagtaggat ggaagtttgt ggatgtgtag
    28201 gaaaagcaat agagacagtg aagtgttaat aataaaggga aagaataagt aagattaaat
    28261 taaggggtgt ctcaaaatga actttttagt tcatgaggca ctcttttttg tatgaaatta
    28321 aatatatttt catcattctg acaataaaaa agaagattat atctattttg agacagcatc
    28381 ttattttatt ttttgattaa tattgtaatt gagaaatttg aaataaggaa gatgatataa
    28441 ttaaataaaa aagttctttc taagtttaaa ttaatattaa aaagttataa tatggtaaga
    28501 attatccagg tagatgactt ctatgatgga tatatgataa aataattttg tatggtatat
    28561 ataataatca taaaataaga gtattgcatt agttttttaa ctaaaacatg taaataggaa
    28621 aaataattta ataactgtgt agtaaaaact tggatttaac ataagacact aactattaag
    28681 gcgtacgact aaaatatata tttaaattat tttatgaaca ctggagggaa agtcatatat
    28741 gattacagga gaattaagga gcaaagtaga caagatttgg gagacatttt ggactggtgg
    28801 attaactaat ccattagaag ttatagaaca atttacatat cttttattta ttaaaggatt
    28861 ggatgaagta gaaacaaaaa atgaagcaga agcaactctt ttgggagttt cttttgaaag
    28921 gatatttaat gatgaacatc aacatttaag atggagtaag ttttctaatg aaggaaattc
    28981 agaaaaaatg tatgaaatag tacaaaatga agtgtttcct ttcataaaaa aattacatgg
    29041 aaataaagac tcagcttatg caaagtacat gggagatgca atatttaaaa ttcctacgcc
    29101 tcttatgtta tctaaaatag ttgatggtat tagtaattta gaattaagta aggatagaga
    29161 tacaaaggga gatttgtatg agtatttatt atccaaagtg gctacagcag gtactaatgg
    29221 tcaatttagg actccaagac acataataga tatgatagta agacttatta aaccaacacc
    29281 agaagatatt atagtagacc cggcagcagg ttcagcaggt tttttagtat catcacaaca
    29341 atacttaagg gataatcatt caagtctttt cttagtgcaa gggctgaagg agcattttaa
    29401 taatggtatg ttctatggat ttgatatgga tagaactatg cttagaatag gtgctatgaa
    29461 tatgatgttg catggcgttg acaatcctaa tatagagtat aaggattctt tatcggaggt
    29521 taatacagat aaagataagt ttacattggt gttagcaaat cctcctttta agggaagttt
    29581 agattatgaa gcagtgtcag cagatttatt aaaagtgact aagacaaaga aaacagagtt
    29641 attattcttg gcactttttt taagagtttt aaaaattggt ggaagatgcg catgtatagt
    29701 gccagatgga gtattgtttg gttcaacagg tggacataaa tcgataagaa aagaaatagt
    29761 tgataatcat aaattggaag ctataatatc aatgccaagt ggagtgttta agccttatgc
    29821 aggagtatct acagctataa tgatatttac taaaacagga acaggtggaa ctgataaggt
    29881 atggttctat gatatgaaag ctgatggtta ttctttggat gataagagaa atgagataaa
    29941 ggatagtgat atagaggata ttattaagag atttgataat cttgatggtg aagtagatag
    30001 aaaaagaaca gagcaaagtt tttttgttga tgtggaagag ataagagaga atgggtatga
    30061 tttatctatt aataagtata aagaggtagt gtatgaagaa gtagtttatg atgctcctag
    30121 tgttattatg ggtagggtta aggcgttaga gaaagagata gtggatggat tagaggaact
    30181 agaaagaatg ttagaggtgt agagtatggt tgatgaagca aaaattttag atgttgttag
    30241 tataagcggg gaaaatgtaa aaaagtttga tggagaacgc tcatatctta gtactggaaa
    30301 cttagatttt aacaagataa gcaatctaga aatagttact tatgaaaata aaccttctag
    30361 agcaaatcaa actgtaaata taggagaagt tatatttgca aaaatgaagg acacaaagaa
    30421 aacattagtt attaataaaa ctaataaaaa tataatagta tcgactggat tttatgtttt
    30481 aaaaccatca aaagaaatat tgcctcaata tttataccat tacttaaata gtagttattt
    30541 tctaaatcaa aaaaataggt taagtaaagg tgctacacaa tcagctttaa ataatgaagg
    30601 attagctaat ataaaaatac gcatgtataa tttaaaagtg caagaaaagg tagtgcgtgt
    30661 tttagacaag gctcaagagt taatagataa aagaaaagag caaatagaag tattggatga
    30721 attagttaaa tcaagattta ttgagatgtt tggtactcca tcaaagaatg aaaaaaactg
    30781 ggaaatttca gaaataggga aatatttaga tgttttaact gattatcatt caaatggtag
    30841 ttatgaaacc ttaagagata atgtaactct tttagataca aaaggttatg ccttaatggt
    30901 aagaactaca gatttagaaa ataataactt tgaaaaaggt gttaagtata tcgatgaaca
    30961 tgcatataat tatcttgaaa aatcaaaggt gtttggtggt gaggttataa taaataagat
    31021 aggtagtgca ggtaaagttt atttaatgcc atttttaaat aaaccagtat ctttagctat
    31081 gaatcaattt atgcttagat ttaatgaaga taaagtgaat catatattct tatataacct
    31141 tttactaaca tcctatatgg aaagtaaaat aaaagagaaa gtaagaggag ctgtaacaaa
    31201 aacgataact aaagatgctg ttagaaaaat aaatattatt gtacctccta ttagacttca
    31261 aaatcaattt gccaacttcg ttaaacaagt aaactctttg aagtttgaaa tggaaactag
    31321 cttaaaagaa ctagaagaca actttaactc attaatgcaa aaagctttta aaggagagtt
    31381 attcaactaa aatacaatta ttaaaatggg ggaataaaat ctatgaatca aatagagcta
    31441 gatttatacc ataacatggt aaatatctat aaagaagctg atttacaatg taactataag
    31501 ccaacaagat ttttacaact gataaataac aaaggagcct tattagctgc taaagaatta
    31561 atcaataaag aaggagctac tgaaggattt acaagactat gggagtgtaa gagattagat
    31621 ttatcattag aagtattagt attaaaagaa aagtataaag agttgtttac tgatgaagaa
    31681 agagaaatat gtataaatag attaaaagat tatggatata aatttaatta agtaatatta
    31741 cctaataaac aagaggtgat taaatgagaa atataccaaa tgagattaaa aactcaataa
    31801 taaatgtatt tccaaaagaa aatactctag caatcataat atttggtagt tatggaacag
    31861 ataaacatac atcagaaagt gatatagaca tagcttggat tcctatcaaa aaagtaccaa
    31921 ttacagaact tgcaactaag acagaagctc taagaaatat attagacatt gatgtagacc
    31981 taaaaattgt tacagataat tatacaatag cacttaaaaa agctatttta gaaggtgaag
    32041 ttatttatga atctaaagat tttaaggatt atataaataa attctatttt gaaaacagtg
    32101 atgtaataga tatcttagat tggagggaca tgtatggtaa ttagaaacaa attatcttgg
    32161 aactcaatag aagaagtaaa tagggatttt ggttcttgct tgtatgacct gcaaaacttc
    32221 aaaatcttat atgataagga agaaatgcct gagttatggg ctagatacat aaaagaaggc
    32281 tttaaaagct atatggtatc atttctagaa ttaacaaaag caatgttgta ttataaatca
    32341 attgatttaa acataaaatc taaaaacttt tatgactacc ttttagcttg tgagtatcac
    32401 aatttattac ctaaaaattc ttctatagtt atagaaacac ttagaaaatt gagaaatgat
    32461 gattctcatg gatatgatat accacagttt gaagatatgt acgaattgtt tacagaaaat
    32521 gaagaagtat ttgttagtat aagaaacagc tgtaagaaat agtttttaga gagatttatt
    32581 ttaactaagg gacaaaaggg ggataaaagc ttgggtaatt ttgatttttt acaaaagaag
    32641 aaaaatttca atagttttaa tactgcttgc ttagaagcag aaaaaagtat actagttagt
    32701 ccatctactt gtgcaactat aacaagaaga gctttagagc ttgcagtaaa atggctatat
    32761 gctaatgata gtgatttagt attgccttat caagataatc tcagtacgtt gattcataat
    32821 aatagtttta tagaacttat agactatgat atgttacctt tattaaaata tatagttaaa
    32881 ttaggtaatt tatctgtaca tactagtgcg aacatagaga gaggagaagc aatactttca
    32941 cttaacaatt tgcatcaatt tgttagttgg atagactatt gttattcaga tgaatataca
    33001 gcagaagact ttaatgaaga tttattactt tatggggaag agaaaaggac gagaccggac
    33061 gaacttaaaa atctttatga gagattaagt tcaaaagata aaaagcttga agaagtaata
    33121 aaagaaaatg aggaattaag aaagtcacta actgaaaaga gaaaagttaa tactgtaaac
    33181 tatgatttca agatagacga agtaagcgaa tttgagacaa gaaaaagata tataaatata
    33241 gaattaaagc ttgcaggttg ggaatttgga aaagatatag gggaggaaat agaagtacaa
    33301 ggtatgccta atgaaagtgg tgtaggatat gtagattatg ttctttatgg tgaaaatggt
    33361 aagccattag cagtagttga ggcgaaaaga acgagtaaag atccaaaaat tggtcaacaa
    33421 caagctaaat tatatgcaga ttgtttggaa aagagatata gtcaaagacc agtaatattt
    33481 ttgactaatg gttttgatat gtatatttgg gatgactatt cagatagaaa agtttatgga
    33541 ttttataaaa aatcagaatt acaacttatg atagatagaa gaaagagtaa gaagtcttta
    33601 agttctgtaa caataaatga tgaaatatcc aatagatatt atcaaaaaga agctattagg
    33661 gctgtatgtg aggctcttga aaataagcaa cgcaaaactc ttttggtatg tgctactggt
    33721 acaggaaaaa caagaattgc tatatctata gttgatgtac tttcaagaca taattggatt
    33781 aaaaatatat tatttctagc agatagaaaa gcattggtaa agcaagctaa aaaaagtttt
    33841 actaagctat tacctaactt ggcgttatgt aatttattgg atagcaaaga cagcccagaa
    33901 gatgctagga tgatattttc tacatatcca acaatgatga atgcaattga tgatacgaag
    33961 tctaaggatg gaaagagatt gtttacacct ggccattttg atttaattat aatagatgaa
    34021 tcgcatagaa gtatttataa aaaatataag tcaatctttg attattttga ttcttactta
    34081 atgggtctta ctgctacacc aaaggatgag atagataaaa atacttattc agtttttgac
    34141 atggaaaatg gagtacctac atatgcttat gagtataata aggcagtcga ggatggatat
    34201 ttagtagatt atactagtat tgagtttaag actaagatta tggaagatgg aattaagtat
    34261 gatgagcttt ctgatgaaga gaaggaagaa tatgaaaata catttaatga tgatgagagt
    34321 attggagacg aaatagggaa taatgcagta aatgagtggc tatttaattc tgacacaata
    34381 gatttagttt taaataagct aatgacagag gggttgaaaa tagaaggaga agaaaagatt
    34441 ggtaagacta taatttttgc aaagaataca aagcatgcta gggcaatagt tgaaagattt
    34501 aataagctgt atccaaagta tggtgggaac tttgtaaaag cagttgacta tagtataaat
    34561 tatgtagatt ctataataga tgatttttct gataagaata aattacctca aatagcagtt
    34621 tcagtagaca tgcttgatac aggaattgac atacctgaaa tactaaatct tgtttttttc
    34681 aagaaagtga gaagtaagac taagttttgg caaatgatag gtagaggaac tagattatgt
    34741 ccagatttat taggtgttga tatggataag gagagattct taatatttga tttttgtaat
    34801 aattttgaat tttttaaatt taatcctaaa ggatttgagg gaaataaagc agaaacactt
    34861 actgaaaaat tatttaatat aaaggtaagt atggttaaag aacttcaaga tattaaatat
    34921 atagaaggtg agtatgcaga acttagaaaa gaattgttag aagaacttat aacttctgta
    34981 aaagctttaa atgaggatag ttatatagtt aggatgaatt taagttatgt acataagtat
    35041 aaaaatgaaa atgtttggag caatattgga gcagtagcac aaaatgagat aagagaatat
    35101 atatcaccac tcataacttc atatagtgat gatgaattgg ctaaaagatt tgatgtagtt
    35161 atgtataata tacaacttgc atacttacaa aataataatg caagtaaagg tataaggcat
    35221 gtaatggcta cagcagaaaa actttcaaaa cttgggacta taccacagat tcagcaacaa
    35281 aaatatacta ttgaaaaagc aatgacagag gatttttggg aagattcaga tatatttgag
    35341 gtagaagaag tacgtatatc attaagagag cttattaagt atcttgaaaa gtctagtcaa
    35401 aagatatatt atacaagttt tgaagatatg attgtagcag aatatagaaa tgattctgta
    35461 tataatgcaa acaatcttaa gaattataaa aagaaggtag agtattattt aaatagccat
    35521 aaagatgaat tagcaatatt taaattaaga aataataaaa agataacaaa gcaagatgtt
    35581 gaaacgttgg aggaaatact cttaaaacag ttaggtaatt gtgatgatta taagaaggag
    35641 tttggagata ctccagtaag ccaattagtg agaagactag tgggattgga tagagaagct
    35701 gcaaatgaag ctttttcaga gtttttaaat aataagagct ttaatactaa gcaaatacat
    35761 tttgttaaac ttatagtcga ttatgtagtc aagaatggat ttatagagga taacaaagtg
    35821 ttgatggaag acccatttag aactgttgga agtataattg atttatttga aaatcatatt
    35881 gaagagagaa ataaattgat taaaactata aataaaatta aagaaaatgc atcagagata
    35941 ggctaatgat gttatttagt gcaaaattat tgttaatgat gtagagaata aatttattag
    36001 taggtagtct aatattgggt tgaaatagat aactagatat ggataatgta aatatacaaa
    36061 gagaggtatt gaataattat gcaatatctc tttttaattg ataaataact atgaattact
    36121 catgaagaag attaaataat aatttttaaa attaagtatt tgtatatttt atagaataat
    36181 catgtattta ctttaataaa ataaaaacag gtataaaaag gtatataata aggctttcat
    36241 atacatttat gagtcaaaat tttgatataa tatatagata catggagtta tgaatggaat
    36301 ttatttaact tataggggga gttaatatga aagcaggaga aattgaattt cttagttatt
    36361 tagaggggtc aaacaaaagt tttgtagtac ctgtatatca aagaaattat aactggaaga
    36421 aagaacaatg taaaagattg tttgatgatt tagaggatat aatagattct ggatttagaa
    36481 ctcatttctt agggtcagtt gtatctatat atagtatggg aaaagaatat ttaataatag
    36541 atggacaaca aagagtgact actgtgtcaa tattattgat tgccatgtgt caaataataa
    36601 aagagtttgg ggaatcaaaa ggaattatta caacagaaga acagattaag gagtgttatc
    36661 ttataaacaa gcactcaaga gataaagatg gaaaaataaa gttaaaacca atagcagaag
    36721 atagaaaagc gtactatgaa ctatttgaag aagaaatgaa tacagataga aattctaata
    36781 tagtttcaaa ttatttatat ttttataata gaataaaaga agataatata tcaatagatg
    36841 atttgtttga tgctatacag aaattaacta tagtagaaat agagttaaaa aatggtgaag
    36901 atgaccctca attaatcttt gaaagtctaa attcaactgg cttagattta agtgaagctg
    36961 atagagtaag aaactttgtg ttaatgggta gaagctctaa gttacaagag gaattttata
    37021 ataattattg gtataaaatt gaaaaaaata caagtagcaa cgtaagtagt tttataagag
    37081 actatttgac tataaaggag agaagtatac cgaataaaaa taaagtatat tttagtttta
    37141 aaaggtatgt atcagataat ggtatagata tagaaatttt attaaaagat ttacttaaat
    37201 tttctaacta ttatagagag atatcttatt catgtactga tgataatgat gtaaacaaag
    37261 ttttgaaaag gataaacaaa cttgaaatat ttgtatcata tccgtttata ttagaattat
    37321 ttgatgatta taatgaaggt ataataaata aaaaagtact tgtagaatcc cttaatttag
    37381 tagaatgttt tatattaaga agaatagtat gtgatgtacc tccgaatgca ctgaataaag
    37441 tatttatgaa cttaggaagg gaaattaaaa aatttagtga ttataaagaa aactattcta
    37501 atatattaag atatattttt ataaataaga aatcatctca aagatttcct actgacagtg
    37561 aattttcaaa tgcttttgaa actaaagata tatataatac taagtcaaag aataagttat
    37621 atatacttga gaggttagag aattataata ataaagaaat tgttgattta gaaaatttaa
    37681 tcaataataa tatgctaaat atagagcata taatgccaca aacattaaca aataaatgga
    37741 aggaatcact aggagataac tataaggaga tacatgataa atatttacat acaattggaa
    37801 atttaacttt gacaggatat aattcaaaac taagtaataa aacatttgaa gaaaagaaag
    37861 aaatggaaga tggatttaaa gatagtaggc tttatctaaa taaatatatt tcatctatag
    37921 ataaatggaa tgaagaagaa ataaaaaata gaactaagat attactagat agagctgtag
    37981 aaatttggaa atatccaagt gttacatatg aacctccaag taacagtgaa aatatattta
    38041 cgttagagga tgatgatgtt aattttacaa atgaaagtat agtatcattt agtatattag
    38101 gagagtcata taaggctaaa aattggacag aattttatga acaagttgct cttactttat
    38161 atgatttgga ttctgtaagg tttaacagta ttgtagacaa aacttataaa agagatttta
    38221 tagataatat taagtctaga gatgcatata aattaagaaa aggtattaaa atatcagaaa
    38281 atatatattt agaaacaaat ttaaatacag aggctaaatt aaatataatt agatttttac
    38341 ttaatgagtt tgatatagag ttaaatgaag taatattttc cataaaataa tgaaatatat
    38401 gcattttttg cgtaatagaa tattaattat attaaaaata aaatagcacc tcttgatata
    38461 gatttatagc tcaaatttat atcaagaggt tacgtttaat taaagtaata caaatactat
    38521 ctaattaaat tattaataaa aatgttatat aaaaatgagt atatagcatt ttaaagagta
    38581 ataaacctta cataataaat gatttattaa tatgaactag aagtattttt actatattgt
    38641 tttataaaac ctttaggcat tttacttata aaatatacca ccataataca agacaaaggt
    38701 ttgtctacta tattactaag aatccttgga aagaacgcag cagtaaatat cttctgacca
    38761 gactgaacta aaaaaccaac caataaatca gcaccacttc cacttaaacc accaaacaat
    38821 aaaactgaaa taggagtacc aattaaagga caaacaatag ataaaattac tcctgtaata
    38881 atagcttctt tataaccaaa accttttttc ttagaaatat atccaacaat aagaccaaga
    38941 acaatattta caagggcaaa aggtatattt gtaggacctg atataacacc taaaactaag
    39001 tttgtacatc caccaataag agcaccccaa aaaggaccta atacgacagc cccaagtaca
    39061 gtaccaactg tatctaaaaa taataatggt atatttatca tagatataac catacctaag
    39121 acaatattaa taactatgca cattgaagaa aatgtgactt ttttagtatc caattataat
    39181 acctcctaaa aaaatatata catttatcat agtatagatt ataaaagatt actaattgta
    39241 tatttctata tagaatattg gaaatataga acaaataaat aatataatta tcaaaatatg
    39301 tagtatcatt aaaattaaga ataactaagg agattattat gaaaagaaat agagagattg
    39361 tagtagtatg tcattgtata ttaaattgta attctaaagt ggagggattg tcagaattta
    39421 agggagcaca aaatatagcg atagatttaa taaataaagg gtatggaata attcaactac
    39481 catgcccaga aatgattatg tatggaataa ataggtgggg acatgtaaaa gaacagtttg
    39541 acaatttgtt ttttagagaa caatgtaggc aaatgttaat acatcatgta aggcagtttg
    39601 atgaatattt aaaaaatgat tatgatataa aaagtatcat tgcaatagat ggcagtccaa
    39661 gttgtggtta taataagaca tgtagttcta aacgttggtt tggtgagtta agtggttgca
    39721 atgaattgat ggataaaata aatgatatac aaatggtgga tgggaaaggt atttttatag
    39781 aagagctaga aaagctactt aaagaatata atttaaatat acctatagtt ggatttgacg
    39841 agcttagaga agataagtag agatataaat atttattgtc tcattatgaa acaccattat
    39901 atttggcaga aaaatatgac tgatggacag tacaggaacc atttttaagt ggagtaatta
    39961 gtacttataa agatgtatcc actagttgaa agaaaatgta gagaggtaat aaatgaatta
    40021 agaagtagat aatatatata aaggagtgtc taaaagtgaa ctttttagtt tatgagacac
    40081 tcttttttta tattaaatca agtatattaa atcaaatata ttttaatcat tttagcaatg
    40141 aaaaataaat ttatctatat tttgagacaa catctttttt agttttattt atttgttgtc
    40201 gtttttgact tggtatacaa ttatatattt tattaaataa tttcataaat tatttataat
    40261 tataaaatcc attgttttga acaatatcta atatattatt atctgtattt ataaggtcac
    40321 tatacatatt ttcaagtccg atattatcta cataataggc aaactttatt cctgtatgtg
    40381 ttttaaaaaa actagatgta tataggtatc atcacagata ttaaaagtat aaataaaaga
    40441 tattaagaac gactttccag caatatatta gaaaatttta ctaaaatccg gaaagcgatt
    40501 gacaaacaaa gtcaaataaa gtatattatt ggtaagttag tttaatgtac aaatgaatta
    40561 tatataaaac ctaatttata aataacgata ctaaacgaca ttatttaact taagctacac
    40621 aaagatagaa tattatacca ttgatttagg aggtagccgt gataaaaata tctgaagact
    40681 atattgaaaa aagatttgac aatgaactat tgcgaataga agcatgggga aaaaactctt
    40741 tacgtattag gtcgtttgta gaccaaaatt ttgttgatga aaactatgct cttaacgaaa
    40801 aacctaagtt aaataaagat gatattacaa ttaataaaaa tgaagatgga agtgcaatca
    40861 ttaaaaatgg aaagataaaa gctgtcttag accatagaga tagaattact ttttataatg
    40921 ataaaaatga aatattattg aaagaatata ttcgattaag agctgtaaaa catgatgatg
    40981 gtggagaaga tgtagggaca attgagatta ccaaagactt taactctact ctaaagttaa
    41041 aatcaagaga atatcgacca agctatagtg gagaatttga agtaactact agatttgaat
    41101 ctgagccttc tgaaaagatt tttggaatgg gacaatatca acataaattt ttagatttaa
    41161 agaatactgt tttggagtta gcccaaagaa attctcaaat atcagttcct ttttatattt
    41221 ctagtctagg ttatggactt ttatggaata atccgggaat tggaaaagta tcttttgcta
    41281 aaaatatgac agaatggaag atgttttcta caaattttat agattattgg attacttgtg
    41341 gagaaagccc aaaagagtta aataaaaatt actctcaagt tactggaact gttcctatga
    41401 tgcctgaaaa ccttttagga ctatggcaaa gtaaactaag atatagaact tcagaagaag
    41461 ttttagatgt tgtgaaggaa tattctaaaa gaggaattaa gctttcatca attgcaattg
    41521 actattttca ttggcctaag caaggtgaat ataaatttga cttagattat tggaaaaatc
    41581 ctaaagaatt agttaaaaaa ttgaaagaag agtattcagt agaaccaata gtatctgtat
    41641 ggcctacagt tcaaagtgat gcagaaaact acaatgatta tttagaaaat ggctatttag
    41701 tcaatgttaa tcgtggtgtt agaatgacaa tgcaaattca aggaaataca gtctttgtag
    41761 atatgacaaa tgaaaatgca agagaatatg tttgggatag aatagataaa aattataaac
    41821 aacttgggat tgactattat tggttagatg tagctgaacc tggctattct gtgtatgatt
    41881 ttgataacta tagatataaa aaaggaaatg ttttaagttg tggtaatatt tatcctattg
    41941 attatttaaa aatgatttat gatggtttac ataatgacat agagtctgtt gtaactcttg
    42001 taagaggagc ttgggcagga gctcaaaagt atggagcttt agtatggtct ggtgacattg
    42061 attctagttt tgaagctttt aataatcaag taaatacagg gttaaatatg ggactggcag
    42121 gtataccatg gtggactact gatattggag gtttccatgg aggaaatcct aaagacccag
    42181 aatttagaga acttatggta agatggttcc aatatgctac tttttcacca attttgagaa
    42241 tgcatggaga tagattgcct catagtaaac cattatcaaa taaaggtgga ggctcaatgg
    42301 taactggagc tcctaatgaa atatggtctt atggtgaaga agttgaagta attcttacaa
    42361 aattcataaa aattagagag agcttaaaaa cttatttaaa aaaactgatg aaagaagcac
    42421 atgaagatgg aacaccagtt atgagaactt tattttatga atttcctgaa gatgataaaa
    42481 cttgggaggt ggataataca tatatgcttg gagatgaaat tttagtagct ccaataatga
    42541 attataaaga tagaagtaga aaagtatatt taccaaaagg acatacatgg gaaaatatat
    42601 ttagtggagt tagttatgaa ggtgggaaaa cttatgaagt tgaatgccca ctggaagaaa
    42661 ttcctatttt cctaaagcaa gattccagtt ataattttaa agaactaaaa aatattttgg
    42721 gagaggtgaa atcataatgg agccacaatt atggcaatta ttattaatcg tactatatgg
    42781 attttttata aactatgaaa aaaattcaac aatgtttgga acatatcaac cagtaacagc
    42841 aggttttatt actggtctta tcttaggaga tataaataca ggattatata ttggaggtac
    42901 attacagcta ttatcattag gtattagtaa ctttggtgga gcatcaatac ctgattatca
    42961 aacagcaagt atagtagcca catttataac tattacgact aagcaagaag catctgtagg
    43021 aatctctata ggtattccag ttgctttatt gatggtacaa ttagatgttc ttagaaatac
    43081 tattggtata tggctagttc ataaagcaga agatggagct aaaaaaggaa attataaaaa
    43141 tataacctat atgcaaatgt taggagtact attaacagca gctacaacag gtattccagt
    43201 tgctctatct gtaatatttg gaccttcttt aattaatacc attttgaaat atacacctga
    43261 atggttaaca ggtggtttaa cagtagctgg aggactactt ccagcagtag ggataggatt
    43321 attacttaga tatcttcctg ctaaggagta ttttagttac ttagtaattg gttttgtttt
    43381 agcagtatat atgaaagtac cattattagg tgtagcttta attggtggag caattgcact
    43441 tataatttac aaaaagaatt tggaaaatca agaacaacaa tatactgtag taggaggtat
    43501 ggacgaagat gagtgataag gtatcattaa ataaatcaaa tgaaaaggtg aaaaaaagtg
    43561 tcttatggcg ctggtttttt actagttctg tttcttcaaa ttatgagaag atgcaggcct
    43621 tggcatactg ttatgcagta ctaccttttt taaaagtagt atacaaagat aatccagaaa
    43681 agttacaaag tgctgtatta aatcatttac aattttttaa cactaatcct tgggttgccc
    43741 cttatatttt gggtattaat gtagcaatgg aggagttatc aagtgaagag actgaagagg
    43801 ctgttgcttc aattaaaaca ggcttgatgg gaccagtagc aggtttagga gatagtttat
    43861 ttgtcgttat tccgtggaca atttttggag ctatagcagc taatatggcg atagatggaa
    43921 gtccgtttgg aatcttactg tggattgtag tgagtgtagc attgaaatta ttaagtatac
    43981 cactatttaa tgctggttat acatcaggta ctaagctaat atcttcaatt gaaaaaagtt
    44041 taaagatttt aactgagagt acatctattt taggtttaat ggttgtaggt gcattaatac
    44101 cttcagttgt aaaagctaat gttgctttga actttcaaca aggtgatttt acaatgaaag
    44161 gtcaagaaat attagaccaa attatgcctg ggttagttcc tgcaattcta gttgtgattg
    44221 tttattgggc tcttaaaaag aatataaaac ctatatactt aattttagga gtaatggttg
    44281 tttcaataat tttatatgca ttaggtattt taaaataagg aaaggatgat attagatatg
    44341 gaaatgaaag gtattaaaaa tattcgtata gatgaccgtt taatccatgg tcaagttgca
    44401 actatgtgga gtaataaatt gggtgttaca agattaatgg tagtaaatga tgcagtagct
    44461 aacaattctg ttcaaaaaca agttttaaga atggctacac ctgcaggtat agcgtcatct
    44521 ataattacag aagagactgc tataaaaaat attactgcag gaaagtatga aggacaaaat
    44581 gtattattaa ttgttaagtc tcctgtggac cttattccat ttgtagaggc aggatttaaa
    44641 atacataata taaatgtagg aaatatgtca agtagaaaag atacaacagt tctaagacct
    44701 aatatcagtg ttactgaaga agagaaagaa gcatttaaaa gacttttaga tgaaggaatt
    44761 gaaattacaa ctataatgac gcctgatgat aagaaaactt atcttgtaga catcttatag
    44821 atttaaagag gtgtattaaa ttgaatagta ttattttgat gagtcatggc aatatggctg
    44881 aagaagtctt aaattctgca aaaatgataa taggggattc tatagattat cctactgtaa
    44941 atatgaaaca agatgatgga atagaaggaa caatagaaaa attaaaaaaa gctttagaag
    45001 tgtacaagga aagttcagaa ataattataa tggcagattt actaggtgga actccatgta
    45061 atgctgcttt attagtagcc aataatgaca gtcgaattaa aattatttca gggctaaatt
    45121 taggtatggt tattgaatca gcttttttag atacaaagga attggcagca aaattagaga
    45181 aaataggtaa agataatatt tctatggttg aacaaaatgc aagtttatta tctgatgatg
    45241 agtaggaaga ttatattaat atttaaaacg aaatacttat gttaatattt aattgatata
    45301 caatttttaa aaaatatagc taatcttgca taaactatat aataaatcta attttagaat
    45361 gtataattta aagggttatg gctgtatata gtcataaccc ttatatttca ttaattaaag
    45421 ttaaattttg tatattcaaa aagctcttga tatttacggc agagccacca tatagagatg
    45481 cctcagaccc taatgatgaa atttctatat ttattccttt gttaaaagag ctaactaaca
    45541 tatcttttgt aatctgtaat atctcaggga tatcactaat tatttggcta tttaaatata
    45601 ttatttcagg agcataagtt gtaatagcat tatttatagc tattgttaag taactacaaa
    45661 actcatgaat aacttttttg gcattctggt tatcttcata atatagttgc tttactatat
    45721 cagaatctat tttaggaata ttttctaaag aagaaagctg ttcaaatacc tttttttctg
    45781 aacaatactg ttctaaacag ccacgatttc cacaaggaca tagtttacca ttaggcatga
    45841 tgatagtgtg accaatttct ccactcatac catttctgcc actatataat ttattattta
    45901 ttataatgcc tgaaccaaat ccactgtgaa tactgagact aagtagtgag ttatgtacag
    45961 ttgaaaaagt attctcagct aaagctgtta agtttgcttc attttctata tgaataggaa
    46021 agtcatactt tttgctaagg atgctatata agtcaatctc attaagattg taatatggag
    46081 taaacaatac tttattttca caagtaatcc catgtatagc caaagtaaga ccaattacct
    46141 tataaggagt gtctattttg gatatgttat aactatttat aatttcatct atcaattgta
    46201 taacattgtc tttacttact tgtatatctg ttaatttctt agaatttata atagttccat
    46261 ctaagtaaga tagagaagaa aatatatagt cgtatccaac gtccatactt aaagaaatcc
    46321 ctgcacattt attaaatact aataatatgg gttttcttcc gccactatga gtactatttc
    46381 caattcctat ttcatgaact agagattcat caataagttt tttggtaata gcggatatag
    46441 ttgctttatt caatcctata gtagaagcta tacttgccct agaaatagga ccatttttta
    46501 taatttgttc aagtaccaat ctttcattca tttctcgaat agtgtattta tcagtaacca
    46561 atttgatatt cctccttaaa ataatattgt aatacttttt acacaaaaat aaaaggttat
    46621 tttgcattga caaagataat taaatatttt attattagtt cataagttag tttaatatac
    46681 taacaaaaat aaagcaagta aaatatacct aaaatataaa aaaattagga taggaaaacg
    46741 atagttatga agtggcattc aaggagggat gaagttggag tatgtattag gtgtggatat
    46801 tggtacatca ggtactaaaa cagttttatt tgataaacta ggaaatacta taaaaagttg
    46861 tacatatgaa tatcctctta tacaagagaa atcaggttgg gcagagcagg atgcaaatga
    46921 ttggtggaaa gctgtagtcg aatctataag agaagtagtt caaagttcaa atataagcag
    46981 tgaatgtata aaaggaattg gattatcagg acagatgcat ggtctagtta tgctggacaa
    47041 tgaaggtaaa acattgagaa actctataat atggtgtgac caacgaacag taaaagagtg
    47101 tgaggagata actgatttag taggtgaaga aagactgatt gaaataactg ctaatccagc
    47161 acttacagga tttacagcat caaagatatt atgggttaga aacaatgaac cagatatata
    47221 taaaaatact aataaaatac ttcttccaaa agattatata agatacaaat tgacaggtga
    47281 atatgctaca gaggtatcag atgcaagtgg tatgcagttg ctcgatataa gaaaaagaga
    47341 ttggagcgat gaagtactag aaaagttaaa tatagataaa aatcttttag gtaaagttta
    47401 tgaatcacaa gagattacag gttatgtgac tagagatgta gcaagtttga cagggcttaa
    47461 agaaggaaca atagtggtag gaggagctgg agaccaagca gcaggagcta taggaaatgg
    47521 aatagttaaa gatggagtag tttcatctac tataggtaca tcaggtgtag tatttgctta
    47581 tacaaaagag ccaaaaattg ataaagaagg tagagttcat actttctgtc atgcaatacc
    47641 aaatacatgg catgttatgg gagttactca aggagctgga ttgtcattaa aatggtttaa
    47701 agataatttc tgtcaaagtg aagtggaagt ttcaaattct ttaggtgaag atgtatatga
    47761 gattataaat aatcaagtaa gtcaagtacc aacaggatgt aatggattgc tttacttacc
    47821 atatatgatg ggagaaagaa cccctcatct tgacccttat gcaagaggtg tgttctttgg
    47881 attatctcca atccattcta aaaaagaaat cgcaaggtca ataatggaag gtgtttcata
    47941 tagtcttaaa gactgtatgg atataataga gaatcttaat atagacgtta atgaagtaag
    48001 agcctcaggt ggaggtggaa aaagtaaagt atggagacag atgcaagcag atatgtttaa
    48061 tcaagatgta tatactataa attcaagtga aggaccagca cttggagttg caattcttgc
    48121 attagtagga gctggaatat atgaaaatat acaaaaagca tgtgatgcta taataaaaac
    48181 ttcaactaaa ttagaaccaa taagtgaaaa tgtagataca tacaatatat atcatagatt
    48241 gtataaaaga atatacaaat ctttgaaaga tgactttaag ttattagatg aagtagttaa
    48301 tgcaaaaata aataattaaa ttagcttaaa aagaaaaata aagatagaaa atagttttaa
    48361 attaagaaaa catactacat atattatatg tgtaaaatat taggaggaca tgaaatgagt
    48421 gaaatattta aaggaatagg acagataaaa tttgaaggag taaaatctga caatgaatta
    48481 gcatttagat actacaatcc tgaacaagtg gtaggtaata agactatgaa agaacactta
    48541 agatttgcaa tgagctattg gcatacttta tgtggagagg gtaatgaccc atttggagta
    48601 gggacagtag agagaccttg gaataatata acagacccaa ttgagatagc aaagattaaa
    48661 gttgatgcag gatttgaatt tatgtctaag atgggaattg agtatttctg ttttcatgac
    48721 agagatatag caccagaagg aagagattta gaagagacaa ataagatatt agatgaaata
    48781 gttgagtata taaaagttaa tatggaaaag acaggtataa agttattatg gggaactgcc
    48841 aatatgtttg gaaatccaag atttgttcat ggtgcatcta caacatgtaa tgcagatgta
    48901 tatgcatatg cagcagctca ggttaaaaaa gctatggaaa taactaagta cttaggagga
    48961 gaaaattttg tattctgggg tggaagagaa ggttatgaaa ctttacttaa cactaataca
    49021 gaacttgaaa tggataactt tgcaagattc ttacaaatgg ctgtagatta tgctaaggaa
    49081 ataggattca ctggccaatt cttaatagag cctaagccaa aagagcctac taaacatcaa
    49141 tacgattttg atactgctac tgttttagga tttttaagaa agtataatct ggataaatac
    49201 ttcaaaatga atatagaagc aaaccatgca acacttgcag gacatacttt ccaacatgaa
    49261 ttaaatatag caagaataaa caatgtttta ggtagtatag atgcaaatca aggagaccta
    49321 ttattaggtt gggatacaga ccaatttcca acaaatatat atgatgcaac acttgctatg
    49381 tatgaagtgt taaagcaagg tggaatagca ccaggaggat ttaactttga ctctaaagta
    49441 agaagagcat cttttgaggt agaagactta ttcctagctt atattgcagg aatggataca
    49501 tttgcaaagg gattattaat agctcataaa ttattagaag atgaggtatt tgaaaacttt
    49561 actaaagaaa gatatgcaag ttttagtgaa ggtataggta aggatatagt agaaggtaag
    49621 gttggattta aagagttaga atcttatgca ctgcaaatgc cagttataaa gaataagtct
    49681 ggaagacaag aaatgctaga agctatactt aacagatata tatatgaagt agatacaatt
    49741 tctaataagt aattgtgtag taattaaact tggatttttg aataaaataa gtaggatatg
    49801 ttcttgtttt tattctaaaa cggacaaaga taagtatttg taaaaattct cataatcatg
    49861 ataaattaag gatatagact taagtataat tagtttatat ccttaaaatt tctataaaaa
    49921 ataatcattt ctatagttat caatattttt aattatcaat atctttctca actaataaat
    49981 aaaaatcagt aaagtatcta aatttaagtc attataatgg ataaattttt tagcatatct
    50041 tttttagtat atcactgata agaatttact ttcaggatat agcagtaaaa tagatatttg
    50101 aatataattg ttattttata actttcatga aataattttg aaaatacaaa taaaaatttt
    50161 taaatagaat aatagtggaa tatatcttca agaatttctt ttaactgttt aggtgataat
    50221 aaaataatga tacaatgtat taaaatataa aatctgaaag tggatgagaa ttacatgaaa
    50281 aagaaagtat tatttttagt aattatttta gcatttataa tcttattagg taattctact
    50341 tattctcaaa agaatcagtt gtctgaagag gaaaaggtgg atgactttaa ttatgtgtat
    50401 aatgttgtaa agacaggata tccatatcta ggtgtaaata agaggcttaa taatattgat
    50461 tggttagcaa ataaggatga atatacaaaa cgaataaaaa acactgaaaa tgatgaagaa
    50521 tttatagaag aactgtcatc tatattatct gatttaaata ataaacacac agaagtaata
    50581 gataataaga aaagatatga actttttaag aaatcatact ctaataatga ttggtatgat
    50641 tttcttaatg ataaaaaagt tgtggataga tatgactcta tgaatcttaa aataaaaatg
    50701 ccagatgata tttttgtaaa aaaagaatta attttaaagg atgttattaa gggtcagatt
    50761 ggatatatgt atttaccatc aatgtcatca aagaatggct ctataaataa tgatttaaaa
    50821 ataattggag attatattaa cactttagaa aaacataaag ctttaattat tgatataaga
    50881 ggtaatttag gtggaagtga taggtattgg cagggaatcg tatctaaact cataaaaaat
    50941 gatatcaaaa taaatggtta tagaatttat agaaataata atgaaatagt aaaaaaatat
    51001 acaaatgcaa gaaatataaa attaaatcct gtagaaaatt taccagcaag tgtaaaggaa
    51061 aatgcaccta aagaaattat aaaagatttt aatgattttg aagatacttc ctatactata
    51121 aaatctacag atgattcaaa atttaagggt aatatatact tacttgttga tagaaaaata
    51181 tattcatcat cagagtcgtt tgcaatgttt tgtaaagaaa ataaatttgc gactttagtt
    51241 ggtgaaacta ctggcggaga tggagggtgt atagaccctg tattgtttaa tttaaaaaat
    51301 agtggtctaa tagttagaat ggcaagttgt atgtatttaa ataagaatgg aatatgtgat
    51361 gaggaattta aaactattcc agaatttaaa gtaaaagatt gtaaaaggac tgctgatttt
    51421 aaagatgata attgtataag aaaagcacta gaacttgaaa atattaatta ttagataaaa
    51481 gaataaaatt aaaactacat ttttttaaac atcaattata gcagtatttt ttatagtcaa
    51541 ttttatgggc taaatagtaa atataagaat acgctgtaat ttaatgttga atattggtat
    51601 aatatttatg acgattttta attaaagggg gtaatagttt atgagattag aagaaatgat
    51661 tttttttaat tataataaat tgaatgatac agatttatta atatggaaat atataactgc
    51721 aaataaaaaa cattgtagta agatgtcaat aaatgaactt gctatgaaat gtaatgtgtc
    51781 tcgtgcaact attacaagat ttgttaaaaa attagattta aaaggtttca gtgagtttaa
    51841 agtattatta agctgggaat cagaaaaggt tcatgtcata gaaaatcagt catttgatat
    51901 tgcatgtaat tcaataatta agtatgttga agatcaaaaa aataaagatt atgatgcatt
    51961 gtgtaaactt ctttatgaat caagaacaat atacgcttat ggttcaggtg atattcaaaa
    52021 tgtggttgca aaacagataa agagaatgtt cttatcatgt caagaaataa tatatgattt
    52081 tgagggaaga acatttgatg attcttttta caatattgtc agtaaaaatg atgttatgat
    52141 tattatatcc ctaagtggtg agaatgagaa tacacttaat attgctagaa gattaaaatt
    52201 aataggaact aaaataattt caattacaga gtttaaaaat aatacattga ctgatttaag
    52261 tgatgaatca atttatattt cagcgactaa tatctcattt ttacaaatgc accctagtta
    52321 taaattgaca atgttatatt ttatattgat tgagttatta tttattaaat atagtattta
    52381 taaaaggcat agaatgatta cagaagggat tgattgcaaa ttgtagtcat tctttttttt
    52441 atgagaattt gaacataaaa atgtgcaaaa acttatttga ctgtgaataa gctccgaata
    52501 taccctaaag attgtatata tttattaacc tgttaaaata atagatatct aaggccaaag
    52561 ataaactaaa aatatgagga ggggagtaat ttatatgatg aagaaaatac aacgttttgg
    52621 aggggcaatg tttacaccaa cactattatt tgcttttgct gggataatgg ttggattctc
    52681 aattgtattt caaaatcagt caattatggg ttcacttgct acaccagaaa atatttggta
    52741 ccaattttgg ggtgtaatat ctagtggagc ttggatggta tttaatcaat taccattatt
    52801 atttgctatt tctttaccaa tagcacttgc aaaaaagcaa caagcaagag cttgtatgga
    52861 ggctttagca acgtatttga cttttaatta ttttgtaggt tctatgttaa gtttttgggg
    52921 aaaaagcttt ggagttgatt tcgcagctga aataagtgct ggaagtggac ttgtaagcat
    52981 tgctggtatt aaaacattag atactggtat ggttggtgct ttgttaatat caggtattgt
    53041 catttatatt cataatagat tttatgataa agaactgcca gattttattg gattatttag
    53101 aggctcatca cttgtagttg caatttgttt ctttgttatg ataccagttg cattattaac
    53161 ttgttttatt tggcctcata ttcaaaatgt tattagacat ttgcaaacgt tttttataaa
    53221 tagtggaaat ataggagttt ggtgttatgc attcttacaa aagattttaa taccaactgg
    53281 attacatcat tttgtatatg caccaatttg ttatgatagt gttgttgttc caggtggtac
    53341 atcagtatat tgggctactc atattcagga ctttcaaact tcagctaaga ctctaaagga
    53401 aatgtatcca atcggatttt cattatccgg attatcgaag gtgtttggtt cattaggtgt
    53461 atttggtgct ttctatgtaa ctgcaaagcc agaaaaaaag aaaaaagtat taggtttaat
    53521 gattcctgct actcttactg cagtattaac tggaattact gagccgttag aatttacatt
    53581 tttatttgta gcaccacttt tattcctagt acatgcattt ttagatgcat gcttgcaaac
    53641 gatttcgttt gccctaggag ttgttggtga ttttggtgga ggaattatta actgggttgt
    53701 attaaattgg cttcctcttg gaatgtatca ctggaaggta tatgttgttc aagttgttgt
    53761 agggattata ttttcattta tctggttctt tgtatttact ttcttaatta agaagtttga
    53821 tatgaaaact cctggtagag aggaagatag tgaagaaaca aaactatata ctaaaaatga
    53881 atatttagaa actaaagatg aaaaaggaaa taaattgagt aaagcctctc aacaagcatc
    53941 tgaatacata aaattagttg gtggagcaga aaatgttgta gatgttacaa actgtgctac
    54001 gagattgaga ttaaccttga aagatgactc aattatttct aaagaagaag attttaaggc
    54061 agtaggtgca catggtttag tgcataatgg aaaagctatt cagattatta ttgggctttc
    54121 agtaccaagt gtaagagaag aatttgaaaa tttattataa aggagaagga aagatggaaa
    54181 gaaaaagaca gaggatacta attgctggtg ggggtagtac ttatactgct ggaattgtaa
    54241 caatgttaat tgaaagtgtt gctaaatttc ctattgaatc aattaaatta tatgacaata
    54301 atgatgagag acaaagaaaa gttgctgaag catgtgcaat aattgttaga gagaaaaatc
    54361 cagaaattaa atttagttat acaacaaatc cagaagaagc atttactgat attgattttg
    54421 taatggcaca aattcgtgtt ggtttatatg ctttacgtga acaagatgaa aaaattccac
    54481 taaaatatgg ggttgttggt caagaaactt gtggggcagg tggaattgcc tatggattaa
    54541 gaacaatagg tccaataatc gaaatgattg attatatgga aaaatattct ccaaatgctt
    54601 ggatgcttaa ttattcaaat ccagcagcta tagttgcaga agcatgtcgt gtattaagac
    54661 caaattcaag aattattaat atttgtgata tgccagtatg tttagaggaa atatttgcta
    54721 gagttttagg tttaaattct cgtaaagact ttgatgttag atattatgga ttgaatcatt
    54781 tcgggtggtg gacaagtatt aaggacaaag aaggaaatga tttaatgcct aaagtacaag
    54841 aatattgtgc taaaaaagga tatgaggaat ttacacctca aggtcaacac aaagaatcta
    54901 gttggttaga aactatgaga gcagcaaagg atttattgga aatagaaccg actacattac
    54961 ctaatactta tttaaaatat tatttaatgg ctgatgaaac tgttgaacat gctaatccaa
    55021 attatacaag agcaaatgaa attatggata gaagagaaaa ggatacattc gaagaatgtg
    55081 aaagaattat aaaaaatggc acagcaagag atacatggtt tgatgcaagt gaacattctc
    55141 aatttattgt tgaattagct tgtgcattag catttaatac tcaggaaaga tttttactga
    55201 ttgttcctaa taatggagct attgaaaatt ttgcagatga tgcaatggtt gaaattcctt
    55261 gccttgttgg aaaagatatg gttgaaccta tgtctatagg taaaattcca actttccaaa
    55321 aaggtttaat ggaacaacaa gttgcttctg aaaaattagc tgtagaagca tggatagaaa
    55381 aaagttatca aaaattatgg cagtcgttta ctatgagtaa aactgttcca agtgcaaaag
    55441 tagcaaaaga aatcttagat gaaatgattg tggctaataa ggatttctgg ccaactttta
    55501 aataaggaga acaaaaacat gataacaaat aaaataaaaa atatcacagc agtattaaaa
    55561 gatgaaaata tatttctttc agtggttatg gtttgttttc taatattacc tgttttatat
    55621 atagtgtatt tagaattgac atcattattt acaaatattt cattttcaca acttttaaac
    55681 aatgatgtta atgcaagttt aaatttaatc tctaacttta gtgcagtata cagtgcatat
    55741 gttatttaca atataaaaaa gaataaagag ataaaagaaa acatgattgc tttctattta
    55801 gtcttattag ggcagatatt ccaaatttac acaataacta ttgttatcat gtttacctat
    55861 atttataaat ttgttggaat taaacaaatc ataagcagta ttaaagaact acaatgggga
    55921 aagagctata aggctctttt ttcctcaatt gcagtatgct taatatcgtt atttgtaatg
    55981 ataattagaa taaagttaat tatgtagagg agtgtctata atgttcttta aaagaaaaaa
    56041 agaagcaatt acaattaatt cctacattga tggaaaaata attaatcttg gagaaattcc
    56101 tgataaagta ttttcaacta aggtaatggg agatggattt gctatgatag caaaggacaa
    56161 tattcttaaa tcaccgacta aaggagtaat aagttttatt gctcaaacta accatgctat
    56221 aggaattaaa ttgcaaaatg atgttcaaat tcttattcat attggattgg atagtgcaac
    56281 aacaaaaaaa gaaaacttta aattagaagt taaacaaggt caagaagtta atatggggga
    56341 aaagttagta gaaattgata ataagttact tgaaaatact ttatatattc ctttagttat
    56401 tgtagagaat cctaatacgg taaaatatca tctttcaaac ttaaatcagg aaggaaatag
    56461 tggtattaaa gttatcaatt ttgattgatt atgattaata aagcgattaa atttaaattt
    56521 atcatattct attttttctc atatattatt tttgcctttg cttcaacaaa attcacacct
    56581 ttcttatcaa aattaggtta ctcagcgttt gaaagaggaa ttatattatc gagctatgca
    56641 ataaccaata tattgtttca attattattt ggagtattag ctgataagta tcaaacaatg
    56701 aaaaaaattg ttttaattag tttatcagtt tatggaattg catcagttat tatgttttct
    56761 actgaatctg caacttttat aatatactta ttacttgttg ctttatcagg aggattatta
    56821 aatacttgct gtagtttata tgatacatgg ataataggtt gtggagataa tattaataat
    56881 tatttgtcat ttattaagac ttttgggtcg attggatggg ctattggaag tatggtagca
    56941 tcttacttga ttcttagatt ctcatatttt ggattatctg tagcgattgg tttaattgta
    57001 gtattactta ttataaatat actattatta cctgatattg aaaagattaa taagaaaata
    57061 aatgtaacta ataaagatat tattgaatta ttaaaagata aaaaatatat cttactagta
    57121 tgtattttat tcttattata ctcaatggtg gtagcaaata actgtactgt aatagataaa
    57181 atgatagctt taaatgctac aaattctcag atatctttaa agtggtcttt acagtcagtg
    57241 ttagagatac caacatatct ggctggttct tatttattaa aaaaatatag cagtttaaac
    57301 ttattaaaat taagtgctat tatgataaca gttcagtttc tactatttgc tttaacaaat
    57361 gattcaaata tcattattat actgtgtgtt tttcaagtgt tttctactcc tttaatttta
    57421 attacttcaa aaagattaat atttgaagtt tctcctaaaa aacttagaag tagtagccaa
    57481 ttaatagctt taagtatatt tatgggaggt tcatctctga ttattccaac tgttgctggt
    57541 tttttaagca ttaatattgg gtataattat acattaatgg tattaagtct ttttggatgc
    57601 ttagcttatt gcttgatagt cttattgaat tatcttcagg aataattgtt ttaatatata
    57661 gtagtaatat cacttgttta tagtatctgt atttgccaca atcaatgtgt attttggttt
    57721 tttatagaga agaataattg tatagattag aggcttctta ggagcttctt ttctttgttt
    57781 atacaaagaa gtaaatcatg cttttatttt aagatatttc cattataatt ataatagtct
    57841 tccatatgtt acaaaagtgt aatgctaaca gttaaaatgt aatatttact taaggattta
    57901 tttatataaa acctttaaaa taaatatata ttaaaaaatt atggaataaa aggatttaaa
    57961 acaaatgtat taaaaaatat atctcttaca gtcaatgaag gtgattttat atcaataatg
    58021 ggtccatctg gtgcaggaaa gacaacattg ctaaatttaa tgtctacact tgacaaacaa
    58081 acttcaggag aaataatact agatggaatt aatatatcaa aagtaaaaaa taatgaacta
    58141 tcaaaattaa gaagagaaaa aatagggttt atatttcaag actataatct attagacaat
    58201 atgaaactaa tggacaatat agcacttcct ctagcattag gaaaaaagaa aagtaaggag
    58261 atagaagcta aggtattttc tatagctaaa aaatttggat tagaaaatca tttagataaa
    58321 tatccatatc agttatcagg aggacaaaaa caaagaggcg cagcagctag gtcattaatt
    58381 acaaatccaa cagtcatatt tgctgatgag ccaactggtg ctttagactc taaatcagca
    58441 tatgaacttt tagaatcatt agaaaaaata aacagagaaa ataacgctac tattataatg
    58501 attacacatg accctctaac agcaagttat tcaaatgaag tatatatgat aaatgatgga
    58561 aatataaagt gtaaattaaa caaaggaaat agtagaaaag aattttatgg aaaaattatg
    58621 gatatgctag cctctatggg aggtgagatg taagtgagta tacttggaat tgcttataat
    58681 aattttaaga gtaacataag aacttatcta gcatttttta tatctatggt tttttcagta
    58741 gttgtgctaa ctaattttga attattaaga tatggtgatg ctataaatgt gttacaagat
    58801 gaaaataaaa aatttacact atcagtgtta gtagctgtaa taatgatact atcagtattt
    58861 ttatttttct ttatatggta tgcaacaaat atatttttta agaataggtc taaagaaatt
    58921 ggaatattgt cttttatggg attagattta tatactatag gaaaaatata ttttgtagaa
    58981 aatatgctta taggaataag ttcttgtata acaggaataa ttatagggat aataacatct
    59041 agattttttc aagtagtgat aataaagtta tctggattta atataaaggt atctaatgga
    59101 cttagtatag aagctatact atatgctact ttaatcttta tttctatatt tataataatg
    59161 gctgtaaaag gttttataac aatatgtaga agtagtgtaa taaatctaat caatatatct
    59221 aaaaaacaag aaaaaatacc aaaggtagga ataggtatat atatattagc tatagtatca
    59281 attatagtaa taggatatgg ctactatctt tctaccaata taagaactgg agatataact
    59341 agtgtactac ctgttatagg tataataata gtaggtactt atggattatt caaatcagtt
    59401 atgcctgtta tatttgatat tataatcaaa aataaaaaaa tattatttaa tggaaataat
    59461 ataattgcaa taaacaatat aaactaccga ttaaataaaa actataaaac ttatgctata
    59521 atagctataa ttataactac aacaatatca actcttggtg cttcagttgc gatgaagcgt
    59581 atacataaga atgcccaaga acaaagaaat gtgtacacta ttagcatagt ttcaatggat
    59641 aaagatgaag tgaataaaaa acaaatagag aatataataa aagatactaa taagataaag
    59701 tactcagtaa atccagaact aacaatttta aagaaaacag atataaaaga agcttatgat
    59761 acaacagata ctataatgaa atatagtgat ttttgtaata ctcttaaagt gaatggcaat
    59821 gataaagaat taaaagagta tggtgaaaga ttagttagtg gaaataatgt aatagagtta
    59881 aaaagccctc aaacgatagc atcaatagct acaaaagaag ccaagataaa acttgatggt
    59941 cagttatata atatttcaag gggagaagta aaagttccag tactagggac aggacttaat
    60001 caaagtatta tagtggtaaa tgatgataca tattttaaac taagagataa gggtcaacaa
    60061 gtgtattttt atggtgcaaa ggtatttcaa gaagaaaata gtcaagtaat gttcaacaat
    60121 attgaaaaga atttaagttt aaaaaatgtg tatattcaaa atggatataa agctcaaggt
    60181 gagagtcaat ggatgaagtt tgcatatgta gtgcttgtgt ttttattctt agtctttgca
    60241 attgtagctg gaagtataat atatatgaaa atatatagtg atgcatatga agataaagag
    60301 aaatataaga ttttgttaaa aataggtact acagaaaaag atataaatag agctgtactt
    60361 aaagaagtag ctatttttta tactttgcca atgttaagtg caactatatc tagttatttt
    60421 gcattgagat tagcaggaga tttattgatg accgatttat ttggtatata tatactaagt
    60481 ttagtgatat gtttgataat attcataata tatggagcag tatctgttaa taagtttaag
    60541 agtgtagtgt ataaaaatta gttgatatat taataaagag aaaggagatt cttgtaataa
    60601 gagtctcctt gttgattaac taaataattt gggtaataaa ttcatataaa atatgttatg
    60661 atattaataa ttcatagcat agtgaaatat taggataatg gagaatatac aaatgtatag
    60721 aattttatta gtagaggacg atattgattt atcaaaagag attgcattag catttgaaaa
    60781 atggggattt aaagtagaat taattgatga ttttgaggta gtattagatg aatttataga
    60841 taaaaaacca gatgtagtac ttttagatgt aaatttacca ttatataatg gattttactg
    60901 gtgcgaaaaa ataagagcta tttcaaatgt accattaata tttttatcat caagagattc
    60961 tgatatggat ttaataatgg gtataaataa tggagcagat gattacatta ccaaaccatt
    61021 ttctatagaa atattggtta ccaaaataaa tggtataata agaagagtct ataattatag
    61081 tgattctaat agtattttgt attgtgaaga tttgatgttt gatgtgggga aagggattat
    61141 aaaacataag tataaggata aaagtataga gttgactaaa aacgaaataa aaattttaac
    61201 attattatta aaaaataaga atagggttgt atcaagggaa agtcttatga tgactctatg
    61261 ggataatgat gagtttgtga cagacaatgc acttactgta aatatgaata gattgagaag
    61321 taaagttaaa gaactaggtt ttgatgattt tataaaaact aagaagggga taggatatat
    61381 aatacaatgc tagtaaaata tttgaaaggt aggtctaagt atattgctct acctttagtt
    61441 gtagttagta taataaatat ctacttattt gctatagata tttttaaaaa taaatattca
    61501 gagttaatat atttagattt tttagtgctg tttataataa tggtattttt tgttatagat
    61561 tatataaatt ttagaaatag ttacacaaat ttatataatt gtatagaaaa tagtggtgaa
    61621 atagacagtt atttagttga tggacaatct tttgaagaaa atctaataaa agatattata
    61681 gaaaacttaa aaataaaaaa taatagtgac atagagactt ataaacaatc attaaaagaa
    61741 ttggatgagt acatagctaa atgggttcat gaaataaaaa ttccaatatc ttctttaagt
    61801 ataattacag ataggttaag tagcatagaa gatagtttgg atattaagaa tcaggttgca
    61861 aagataaatt ttttagtaaa ctctattttg tatagtagta gaagcaacac tatgtttgaa
    61921 gatgtattta taaataaatt taatttagaa aaattggtaa aaatgtctat aaaaaataat
    61981 tcatttttgc ttataaaaaa taatatagaa gttagtttga atgaattaga aaatgatgtt
    62041 tacacagatt ctaaatgcat gtcatatgtt ttagaccaaa ttattaataa tgctataaag
    62101 tattcaaagg aagttggtaa gattgaattt aattcaaaaa agttagaaaa tggagtggta
    62161 ttatctataa aagattttgg tataggtata aatgaggaag atatatctag ggtttttgac
    62221 aagggattta cggggaaaaa tggaagaaat caattgtata agtctactgg aatggggatg
    62281 tattttgtaa agaaaatgat agatagttta gggcatgaga ttgaggtatg ttcggaaaat
    62341 ggttcatata caatttttaa tatctatttt tatgatatat cagattattt aagcctagat
    62401 agttaggtta ttagactata aaatctatca tcatatacaa atcgacatat acaataagaa
    62461 taaatttagt tcttgaaaat agtgaagatt taattagtgc cttaaatgat gctctatcta
    62521 tattataaaa taataattat tatatatgaa aaacatatca gatatgtacc tggtatgttt
    62581 tttatttgta gtaactattt taatatggtt tttggagaga gaatatgttt tgtttgtgaa
    62641 aaaaaattac atggtattac attgacactg aaaataaatt aatgtaagat ttagctaagg
    62701 taaaaaacgt gtataagatt aactcaatta atttcataag agtaaattat cgtaattaaa
    62761 gatgaaataa gattaattct aaaattatta aacttaatac cttgatttgg ggaggaataa
    62821 ctataaactt aaaaggatga taactatgta tagtgtaggt ttaatgtcag gaacttcctt
    62881 agatggagtt gatgcagtac tagctgaaat tagtgggaat ggtagaaata ctaaagttaa
    62941 gcaaatagaa tttataactc tagaaattcc taaagatata aaagacgaaa taagaaagtg
    63001 ctgtatagaa gaggaatcga gtgttgattt aatctgtagc ttaaatttta agcttggata
    63061 tttatttagt aaagctgtaa aatcagtgtg tcataaagca aactttcata tagcaaattt
    63121 ggattttatc gcatctcatg gtcaaacaat ctttcatata ccaagaagtt ataataattt
    63181 tgtatcttca acgcttcaaa taggtgaacc agcagttata gcatatgaaa caaatacaaa
    63241 ggtaatatct aattttagag taatggatat agcagcaggt ggagaaggtg ctccattagt
    63301 accatatagt gaatttttat tatatagtga taacaataaa aatttagcac ttcaaaatat
    63361 tggtggaata ggaaatatta ctataatacc taaatcatgt aacatagatg atgtatttgc
    63421 atttgataca ggaccaggaa atatgataat agatggagta tgtcaaagat tatttaatag
    63481 aaagtatgat aaaaatggat actttgcatc aaaaggtaaa attaatgaag aaatgttaaa
    63541 agatttgatg agtcataagt atcttagtca agcgccacct aaaagcactg gaagagagat
    63601 atttggacaa gtctatttgg ataacatgct taacaaatat aaacatgtag ataaatatga
    63661 tttgatagca acagtaacta tgtttacggc aaaagctata tattataatt ataaaaactt
    63721 catacttcca aaggttaatg tagatacttt attaattgga ggtggaggag ctcataatct
    63781 aactttaata ggatatataa aagagttatt attagaggtt gaagtattaa ctcaagatga
    63841 atatgggtat tcttctgatg caaaggaggc tttggcattt gtaatcttgg gcaatgaaac
    63901 attaaataat tctttttcta atgtaatatc tgcaacaggg gctaaaaata aagttatttt
    63961 agggaatata acacctaaac cttttggagg taaatgacat gtctaataat aaaaaaaaga
    64021 aaagaaagaa aaataataat tataaaaatg caaaaagtac aaaaagtaat aaaaatacta
    64081 agaaagaaat ggagaaaaat caaagaacag attataatat tccaactata agttttaaaa
    64141 gtggattaat actaatagtt tcatctcttg taagtactgt agtttttcct ttgttattat
    64201 ctatatttgg aatagataat agatttggag ttgttatagg aaattcatta attacatctt
    64261 ttgcagttgc atatacaaga tactttgttg aaactaagag aggtttttct ttgggatttt
    64321 ttagactgta tattttattt gctttatcat ttgcaataat aggttacttc tggatatata
    64381 aaggaataca tatttaaaaa agtattgaga ctattttatg ttaataataa gatagtcttt
    64441 tttctttttt aagaaaagat atgagtattt taagtagtgt gtaattttag acaaaagaat
    64501 gattagataa ataaagcaat taaagcaaga tataaattca tgaaataaaa ttacaaataa
    64561 aaatgtaaaa tatgaaaaaa tatatacaaa cgtattcctg taatcaaaaa tacatgctat
    64621 aatgattgaa aagaaataaa aaaacagggg gaatcaatat gagagtatta tttgtttgtt
    64681 catcagggat gtcaagtgct atagcagtta atgcattaca aaaagaagga gcaaaaaatg
    64741 gaatagatat agatgttttg gctgttggta ctcaagagtt tgaggatgaa gttaaaaatg
    64801 gatgggatat tgctatggta gctccacaag tcagacatag atttgactat ttaaaagctt
    64861 ttgctgatga ggttagtgta ccatgtgcat taatacaagc acaagcttat agtccattag
    64921 gaggaccaaa gttattaaaa caagttcaag aactgttgag taaatagtag ttgcagtgtt
    64981 gttagattag aagaaagttg attttataaa aattttaatg ataataaaaa taaatattaa
    65041 ttaaggagag aaaagatgct agataaattt acagaatttt tagacactaa attatcaact
    65101 tctatggcca gattggcaga acaacgtcac ttaagagctg taagagatgg aatcgtagct
    65161 tcattaccac ttataatagt tgggtcattt ttcttgatat tagcatttcc tccattacca
    65221 gattcatggg gggtaactca gtatctaaag gaaaatgcag ttacaatatt actaccatat
    65281 agaatgacat tttttattat atcagtatat tctacatttg gcataggtta tagtttggca
    65341 aagtcatata agttagatgg attgacagga ggtttattag ctacagctac attccttttg
    65401 acaatagttc ctactgcaat agagggtctt acccctgatt tattaaagat agttgaaaag
    65461 agtccagaac ttttagcttg gtataattca attcctcaag gatggcaaat gccaatggct
    65521 aatcttggtg gaggttcaat gtttgttgct attgtaacat ctataatagg tgttgagatt
    65581 tatagattta ctgacaaatc taaattcaag ataaccatgc cagaagcagt tccagcatca
    65641 gtcacaaggt cttttgaagc tctgacacca gccgcattaa taataatttt aatggctatt
    65701 gttacttatt tcctagggtt tgattggcat ggcttcatag ctaaattagt aactccatta
    65761 gtttcagcca ctgacacatt accatcagta attatactaa tatttttaat aacgtttttt
    65821 tggtcatttg gaatacatgg tgtatcaata ataggttcat tggcaagacc tttatggata
    65881 caattattag atgctaatac agcttcatat gctgcgggtc aagcagttcc aggtattgct
    65941 gctgaaccct tttttcaatg gtttatatgg attggaggtt ctggagctac aataggctta
    66001 gctttacttc ttgcatttag agcaaaatca gcttatggaa agtctttagg aaaagcaact
    66061 gtaataccag caatattcaa tataaatgaa ccaataatat ttggagcacc aatagtatta
    66121 aacccaatat taataatacc atttgttgta gcaccaatag taatggcaac agtttcatgg
    66181 tttgctatga gtgctaattt agtatccaga gtagtagtta ctgctccttg gacattacca
    66241 ggaccagtag gggcatattt agccactggt ggagattgga gagcttcagt tcttaactta
    66301 ttatgtatag ctatatcaat aataatttac tatccatttg tcaagatgta cgataagaga
    66361 ttgcttcatg aagaaaaagt tgaagagcaa gaagcttatt aattagaaac tatattggaa
    66421 attaaaaact atattagatt agtataaatt tcaaagtata acagttatga aataagtaac
    66481 gaagatattt tgttgattgt ttataaaaaa agaaaaggta aacttttctt tttttataaa
    66541 tatatatgaa actttttttc accaaatttt taaaaaagtt tcgtgtaatt cgaaataaat
    66601 ttaaacacat ataggatata aggagatgac acagatggga agattaggaa tatcaattta
    66661 tccagaaaaa acaacatcta aggaaatata tgattatata gataaagctg ctgaaaatgg
    66721 atttacacgt atattttcat gtttattatc agttaaagat actaaagaaa atataattaa
    66781 aaaatttaaa cgtataaatg aatacgctaa gtttaaaggt tttgaggtaa tacttgatgt
    66841 aaatcccaga gtatttggtg aattagaaat aagctacaaa gatttgactt tttttaaaaa
    66901 gacgaaggca gacggaataa ggcttgatat gggatttaca ggttctgaag aggcattaat
    66961 gacttttaat cctcaaaatc ttaaaataga aatcaatatg agtaataata ctaattatat
    67021 agatacaata atggactacc aaccaaataa agaaaatttg ataggatgtc ataactttta
    67081 tccacataga tatagtggat taaatttaaa acactttata aaatgtacag aaagatttaa
    67141 taagtatgga ttaagaacag cagtttttgt aacaagtcaa aatgaaacta catttggacc
    67201 atggcctgta actgatgggc ttccaacaat tgagatgcac agaaatctac ctatagatat
    67261 tcaagtaaag catataatag ctatgaataa tataaatgat ataataatat caaattgtta
    67321 tccaacatat gaggagctaa aggtattagg ttctatgaga aaagatatgg ttacatttga
    67381 tgtagcaata gaggaaaata tacgagaagt tgagaagaag atactctttg aagaaataca
    67441 ttttaataga ggggacatat ctgatagtct gataaggtct actcaatctc gtgttaaata
    67501 taaaggatac aaatttgaac tatttaatac tcctaaaata ataaaaagag gagatatagt
    67561 aattgaaagt agtgaatatg gtcattatgc aggggagtta caaatagcct tgactgatat
    67621 gaaaaacagt ggtaaatcga atgtagtagg atatataaga aaagaagaat tatttatatt
    67681 agattatatt aaaccatggc aaaagtttaa ttttaaaccc tcaacaaaat aatttattat
    67741 gaaaatatta atttattata aaaatataat tatgaaagtt ggaattaaaa tgtgtttaaa
    67801 aatttaatat taagaaaatg aggaaatgat atgttaataa aaactttaga aaatttagtt
    67861 acagaaggta gaaataagaa tacattgcaa atagataaag aagatacatt aggcataata
    67921 gaattaataa ataacgaaga taaaactgta gcctatgctg ttgaagaaca aaaggagagt
    67981 atagcaaaag ctgttaatat aatagtagat agaatgaagc agggaggtag attattctat
    68041 ataggagcag gtaccagtgg gaggatagga atactagatg ccacagaatg tcctccaact
    68101 tacggagtgg attttgagct tgttcaagct ataatagctg gtggaaatca agcaatattt
    68161 aaagcaatag aaggtgctga agatgataaa gaacttggaa agcaagatat aatagataga
    68221 ggagttacat ctaaggatgt tatatgtggt atagctgcat caggaaggac tccttatgtt
    68281 ataggtgcaa tggagtatgc taaggaattg gggtgtgcag tactatcaat aactatgaat
    68341 ccgaatagtg aaatgagtaa aaaagcggat ttaccaataa acattatagt aggggcagaa
    68401 gtaataatgg gctcaactag aatgaaaagt ggtacagctc aaaaaatggt atgtaatatg
    68461 ttaacaacag cttctatggt taagatggga aaagtatact caaacttgat ggtagatgtt
    68521 aagacatcaa atgaaaagtt ggttgaaaga gcaaaaagaa taataatgat agctacaaat
    68581 gtaaaatatg acgttgcaga aaaattctta gaagaagcag ataatagcgt taaattggct
    68641 atatttatga taaaaagtgg tttagataag gatagtgcaa agagtatcct agatagacaa
    68701 gaaggttata taagtgaagc tttaaaatca atagaaaaat tgtaaaataa ataatagtac
    68761 tgataacctt tcaatattaa aaaaacagca ttggaaggtt atttttagat attaagtatt
    68821 gaaagaatta ttaaagatat tgtaggagga tagtatgtat tttttaggtg tagatggtgg
    68881 aggaacgaaa acaacattta cattagtaga tgaagaatta aatatagtag gaaccataac
    68941 caaaggaact tgtcattata atcaaatagg atttgataat ctaacgaaat tattaataac
    69001 tgggttggaa gaagtttgta aagatgctaa gataaatgta gaagaaataa cgtatgcatt
    69061 tgttggactt gctggatatg gaaaaataaa agaagtattg tatgcattag aagtagcaac
    69121 aaaaaatgca tatagtcata taaattatac tctaggtaat gatgtagaaa tagcattagc
    69181 aggttcttta aatggggaaa aaggtataaa tataattgca ggtactggtt caatagcaca
    69241 ggctttagat aaagatggga atcttcacag atgtggagga tggggctatg tattaggaga
    69301 tgaaggttca gcgtattata taggaatggc taccttaaaa atgttcacaa tgcagtctga
    69361 tggaaggtgt tcaaaaacaa aattatatga tttaataaaa agacatctta atatagagaa
    69421 tgattatgac ataataaaat atgtaaatga tgaaatacaa ggagatagaa tagaaatagc
    69481 aaagtttgct acgatatgtt taaaagcagt tattgaaggt gataatactg ctagtaaaat
    69541 atttgatgat gcagcttatg aattaagtag gcttataata ggattagatc atcattttga
    69601 acaaggtaca aagataaagg tatcttattc aggtggagtg tttaagtcag gagatttaat
    69661 attagagcca cttaaaaaat atttgaataa aacgagattt ggtatagtga gaccagtgtt
    69721 gactccagat ttaggagcat gtttacttgc taagaagaaa tattatagta aataggtaga
    69781 ggtggtagag tatgagttgc attttaaaat taaaacagat atatgaagat ttaacggaag
    69841 tagataaaaa aatagctgat tacatactta ataatacaga ggctataagt aagctttctg
    69901 tatcagaatt ggcgtcaaac tcaaaaacaa gtacagcaag tatagttagg ttttctagaa
    69961 aaatgggata ttcgggtttt ggggatttaa aaattgagat agctaaagat ttgatgggca
    70021 aagaaaatga atacacatat gtagatgaaa actatgattg taatatagat agtgttataa
    70081 acaaaattac aaacaaaaac atagagacta tcaaccaaac aaggttgttg aatgaaaaag
    70141 atataataaa agaagcagtt gaacagataa taaaggctaa aaatgtatat atatttggag
    70201 taggtggttc ggctttagtt gcactagatt tacagatgaa acttttaagg ataaataaac
    70261 aggcatttac ctctttagat agtcatacac aacttatggt atcttcaaat gtagataaag
    70321 aagatatagc tatagcaata tcttactctg gagaatcaaa agaagtaata aagtctatag
    70381 aaaatgcaaa attaaaagga tgtaaggtca tttgtataac taaatatagt gacaatcatc
    70441 ttagtaagat tagtgattta aagctagtag taccaaatat agaaaaaaga cttagagaag
    70501 gagctatttc ttcaagaata gcaatgctta cgttgataga tataatatat atttctataa
    70561 ttcaagaaaa cttaaatgag gcagaacaga aactacaaga aacaaaaagg atacttgatt
    70621 atttaaatat taataatgct taaaactagg ttatatatca actaaacaaa taagttaggc
    70681 tataagcgta agtcaataag aaatagataa atatctaaaa tattgactta cttaataata
    70741 atatatagca tttttataat acaaatgagt tgtcttaaaa ttgatttttt ttaatcaaat
    70801 tttaagttca actccttttt tatattttta tagatatatc ctatattttc ccagaaaacg
    70861 tattgaatat acaaattata agaagtataa tgttgttggg agagaatgta tgaaatgtat
    70921 acaaagttga ttttaactgt attattgata attctcttta ctcttaccat tattaatgat
    70981 tgaagacaat ggtatttatt ataggtcaaa gattccgaat gtattaatca tcatcatttt
    71041 ctcaaactaa cagcaaacac cctgatttgc gagttgtatt gtatacaaat tatctagaaa
    71101 atatctatta gattttccat gaaatttaaa tatttcacga atgtatgaat ggagaaatat
    71161 acatgttgac aatccacctt tttaaatcct aaattaattt tattaatggt agagaatagg
    71221 aagtaacaat gttttataaa ggagaatatt aagtatgaag aaaattagga agttagctac
    71281 caagttattg attacaacaa tagttttaat ctcaggtatg agtatgacag tttatggtat
    71341 gacagccaaa gaggtaacag caaaagcacc aaaaagctat gtcactggaa ccaatagcgt
    71401 atatggtcca aagctgtcac aagcccaact aaactcagta gcacaagcaa cagcagattt
    71461 tatgaacaag aaaatcacaa agaatatgac cacagatgct aagattttag ttgcctacaa
    71521 tcacattaaa aataacacaa catatgttga ctggaatgca gtagagggag caaatactgc
    71581 ctatacattg gttactaaaa aaggtgcatg ctcaggaatg gctaggagca tgaaagcttt
    71641 gtgtgatgct atgggaattg aatcttatta tgtacacagc acatcaaatg accaccagtg
    71701 gaatcttatc cgttttggtg atgggcgttt gtatcatgta gatattgatg ctaataaatc
    71761 agcaggaaag gatatcatat acaagagtct tagccaccca ttaccatttg ataagacagc
    71821 atatccaaaa gttggtgcaa tagtacagac ggtaaaacca gaacagacac agaaaccagc
    71881 accacctggg aagcacacta tgttaccaca tcaagaaggg gcaaaggctg ttggaaattt
    71941 tggaaaaaaa ggagaagata taaatgaaaa acatgtaatg tatgaaggtg ttagatgtag
    72001 tgtagttaat tcatcagtaa atacaattac atttacaggt agtgaatcaa atttagaccc
    72061 atcaaatctt acgattgctg taataggatt tatgaacaca ccatatggga tgtttgcatt
    72121 agcaccagag ggtaaacctg ttgaatatcc ttttaaatat gataagccat tttctttaga
    72181 ttttagtggt aaaaatcgtt ctggtgcaga attagcgaag tactgtaaaa aaaatgatgt
    72241 gactattaaa atagaaatca ctgatgaaaa agctaatatt ggacttggtc aaataatgta
    72301 tgttcgatat gaataatgat ttaatcatga cagtagaata agttataaac attgcgccct
    72361 cttactaggg gcgcatttaa tattatatct gatattttgt agtcaggtca actgctagat
    72421 ttctcccctt tttatttata aaaattatta tctctaagca tctgagcatg tttacgatta
    72481 actaaaaact gttttaactc agtcaagcat aggaataaaa tagctctatt ttcaaactct
    72541 gttctgtcaa caggtagagg ctggtttttc atactaagca ttagtctctt taattcttca
    72601 agaagaagat tgcctgtttc agcttcaaat tcagtataac ctatcttatg tataaaagca
    72661 gatagaatat gagcttgtgg tggtgtagaa tttagttgag atacataact atacaaattt
    72721 tctaagatat cccgttgact ttttataata tccatatgct ctaagaagaa tctagtatca
    72781 cttaataaag tattattaat attatcgtaa gtttcagaaa tactgctgtc aataagtgaa
    72841 tttaatgtat ataaatctct actatatcca ttttcttttt taggatttac aataatatct
    72901 gcaatgtcta taagtacaat actcacttct tcctgtaact ttttttgaac ttcatggatt
    72961 ttatgtatat ttgttggaat atacatattt attaagacac ctattccagt tcctactgca
    73021 aatattccag cttcatttaa aatccatttg atagaagttt ctccttgaag gtagtaatgg
    73081 gatgctatga ctacacacat agcaataaca tcttgaatat ttaacaaaaa acaaagtggt
    73141 ataattataa atataaatat tgaaaatgaa gtcaaattat atcctaaaat attaaaacat
    73201 aaatatgaaa aaatagtaca taaaagaaaa ccataaatct ttccaatgga gcctttaaga
    73261 gtttctcttt tagtgtcctt tactgtaagt agtactataa ctccagcaac cattgaatat
    73321 tctaatttta atagccaagc aataaatata gcaagagaac atccaagaga taattttatt
    73381 actttaagtg aattaatatt attcaaatgc aaacctcctg taaatcaata taataaaatt
    73441 ctaacataaa actaatattg cttgaaaggt aagtaactat acttaattat tttattgccc
    73501 tatttgttta gatacaatca atataatttt attttatgaa aattttttgt aaaattttaa
    73561 atttagagac taacatgaga ccacaaagag gaagtttatt ataggaagaa aacttaaaat
    73621 tgattttaag cagcaaatga aaataatcaa atatgtatat actattatta aaaaataaaa
    73681 ttatatagtt aatataattt tataattggt ttagtataga gatttttaac ttttatgtta
    73741 tactatttat aaaagtaggt ataaagatta aaatacataa tcaaatatgt ataagaggtt
    73801 ttaaatagta ttgttaatga acttgattat tgtttataat tacaaattgg aggagataga
    73861 catgaaaatt actgaaggat atatgccttt taaaggtttt aaaacgtatt accgtatagt
    73921 aggagaaaat acggaaggga agaagccatt agtattactt catggaggtc caggttctac
    73981 acacaactat tttgaggtat tggataagat agctgaaagt ggtagacaag taataatgta
    74041 tgaccaaatt ggttgtggaa attcatttgt agaagggcat cctgagctat ttaatgcaga
    74101 tacttggata gaggagctta ttgaactaag aaaacatcta ggacttgatg aaattcatct
    74161 gttaggtcaa tcttggggag gtatgcaggc tatttggtat gctattgaat ataaaccaaa
    74221 aggtattaag tcttacatcc tttcatctac tctttcttct gcaaaacttt gggagaaaga
    74281 acaaaaaaga agaatatcat atatgagtga ggttgaccaa aaagcattac ttgatgcagt
    74341 aaatactgga gattactcta gcaaagaata taatgatgca ttagaaagat ttatggaaat
    74401 gtattgtgca ggtgaagtga cagaagattc tccagagtgc ctgagaagac ctaaaaaatc
    74461 aggttctgaa gcatatattg taggatgggg acaaaatgaa ttttctccta caggaactct
    74521 ttctggatat gaatttacag atagattaca tgaaataaaa gagccttgtc tagtaactag
    74581 tggagcaata gatttatgtt caccatatat tgcaaagact atgtatgata gaatacctaa
    74641 tagtaagtgg gaattatttg agtattcaag acatatgcca ttcgttgaag aaaatgagaa
    74701 atatataaaa gtcttaactg agtggttgaa tgcgaacgat taaaaactat ataaatttat
    74761 ataaaaaaat gagtgtctca aaatgaactt tttagttcat taggcactct ttttgcatga
    74821 aatcaaatat attttcatta tttgaacgat aaaatgaagc ttatatctat tttgggaaag
    74881 taatttttta ttactagcgt tagattctaa tctaattgta tacttattga aataatagaa
    74941 atatattggt gtttataact taattttatt gttttttaga aattttttta tatattggta
    75001 taattattct gtttaaattt gattaaaaag tatattaatt ataataagaa acaattatat
    75061 aaataggaat agattattat aattaatata gatataaaaa taattataga aggaaaggca
    75121 cattatggaa aaattgagag ttattgaaat gataaaaaat aatcccaata ttatagctac
    75181 aatagataat ccaactgatg aaatgaaatt gttagctatt aaagaaaatg ggcttgtact
    75241 agaatatata aataatccaa ccagagagat gcaagaacta gcaatagata ataatattag
    75301 agcaattaaa tttatagata atccaacaga agatatgatg ataaaagcag taaatgaggg
    75361 atggagtata ctggattata tcaaaaaccc aactgataaa gttattgaaa tggctataaa
    75421 tcaagcagga tgggcaatta aatatgctaa aaatccaagt gaagaattac aactattagc
    75481 agtaagaaaa aattatgatt cgataaagtt tataaaacaa ccttatgaaa gtgtacaaga
    75541 ggaggcagtg agaataagtt atgatgcctt gagatatata gattcaccta gttacaatgc
    75601 agaacttata gctataaaaa ataatgaagc agctattagc tttataactg atttagataa
    75661 aaataaaatg ttggaatttt taaaagtgaa tattttagtg attaagtaca ttctgaaaaa
    75721 agtatctaaa gatgaattag agagtgtatt aaaagaagta ttatccaaag aagatgttga
    75781 ggaaaagtat attagagatt ttttgaattg tagtgttata gatagaaata gcgaaagtat
    75841 accaatagat aaaattatgt ttatttataa atatggaagt aagacagcaa aaaaaatagc
    75901 tgtagatgag aaattaaaga ttatgtagga gagagaaaaa tgaattttat agacacatta
    75961 aaaagcgttg acttaatatt atccactgga gaagtacctt taatagtagg tgaaagtgga
    76021 ataggaaaaa cagctttagc aaataagctt gccaaagaaa atgattggag tttaattgtt
    76081 attgatggaa acttacttaa agagggtgaa ataggtggtc ttccaactat agaatcttat
    76141 gtaggagtta attctaatgg atataagact gaaaagaaaa caacagtgta tgctgttcat
    76201 aacaaattaa gagaaattga tgaagagata tctaaaagta agacagttct tttatttata
    76261 gatgagataa atcgttgtga gcatacagta cagcaagaac ttatgaattt aattttaaat
    76321 agagaaatta atggatataa actgcatgat gatgtaaaga ttttagcagc aatgaatcca
    76381 tcaagtaaat atggttcaga ttttgattat caagtggtag atatggatgc agcccaagaa
    76441 aataggtttg tttggttaaa tatggagagt gaccatacac aatggataaa atgggcaata
    76501 gatgagggta ttgaaagaaa agttatcgag tttatttcca cttttccaga atatctgcat
    76561 aaaataaatg aagatgatgt aagagccact cctagaagtt atgagagagt atctaaaatt
    76621 tataaagttt ataaagaaaa aaataattct attcctagag cagtattttt aaatgttgta
    76681 aagggtaatg taggtaaagt tattgcagaa gaatttataa gttttattga atcaaactct
    76741 gaaccattaa tatcctatga agatgttttt ttaggagaat ctattgatga gtctattgta
    76801 gaaagagtaa aaaatgagag tcatacaaga ctttatctat cagctatgaa cattctaaaa
    76861 gacttagaat taaatattaa gaatgataaa tatgaatcaa accactatat taatagattt
    76921 attgaatttt taaaaatgta tcctgtagat ttaatgatag gtattatgaa ggatattaga
    76981 aacagttata ttgaagtata taaaaaagct atagaaaatg aagagtttgt aaaatcatat
    77041 tttgaatctt atagtttaat aaggggataa tgtatggaaa attattttga taaacaagca
    77101 aaagagcttt ataataaagc aagtgaaatt ataaatactc attctatgct aaaggcaaat
    77161 cgtgctaatg agaaatttga tatagatata ccacaagatt ttaagtatga gttttttagt
    77221 cttgtagata aagtgaattt aagtcttatg gaagaagaag ataattttta tggatatttt
    77281 ttgtttcaga tgtcaagaga aataagattt gatataagta gtcctacagg tgtgaatttt
    77341 aagggagcta aatatgttat atattttaat ccaataatct ttttaacgct tgacataaag
    77401 caaatggaga ctacaattaa acatgaaatt catcatatat tatctatgca tttgatgaga
    77461 gcaaaggagt taaaaggaaa gtatagtaca ttagcaatta atatggcaat ggatatagta
    77521 gtaaataaat ttctaaacaa tttaccacca tatgcaacta ccttagagtg ggtaaattta
    77581 aagtattcct taaaacttga accatatgaa ccttttgaat attatgtaga aaagattcag
    77641 actgaattag atttgatgga agtggatgaa gatggtgagg aagatgatag tgataaatat
    77701 ggagatatag aaattgatta tagccccgaa agaactcatg atatatggga tgaatccaat
    77761 gagatagatg aaaataccct tagagaattt actgaaaaat ttattaacag ttctcaaaaa
    77821 ggtaaagttc ctgcttattt agaaagtatg atatcatcac ttaaaaatag taagggtgaa
    77881 ttgccatgga atttatatct taatagaata atgggaacag ttgaaaataa taaaaagaag
    77941 actataacaa gaagaaatag aagacaacca aatcgtttag atttgagggg agaacttaga
    78001 agtcataagt cagaaatagc agttgcactt gatgtaagtg gaagtattag tgatgaagag
    78061 tttaaacaag ctattaaaga agttcttagt atagtgaaaa actataatca tgaaattaca
    78121 attatagaat gtgataatga aattagacgt gtatataaag tgagaactga aaaagatata
    78181 aaagatagaa ttaggatagg tggaggcact agattttctc cagtctttga gtatgcgaat
    78241 aataaaaaga ttaatttgtt agtctacttt actgatggta aaggtgaaaa taaactacaa
    78301 gtaataccta gagggtataa aattttatgg gttatttctg gaagaggaga taaaatttca
    78361 ttaaaagaac cttatggagc agttaaaaaa cttactaagg ttaaaacaaa tgatgaaata
    78421 ttagaaataa atgatgtaag aaatgatggg tactcaatga atagccaagc accaatttta
    78481 taggtattca caggagataa gctttattaa tttattttga tatgcttgtt ataaaaatct
    78541 aaaaaataca ttaatcaatg gttaatgtat tttttaattt taataatata agttttactt
    78601 acatttaagt cttaaaatgt gttaaaatat aatatatagc agatagtttt ggcaaggtgg
    78661 atttagttgt caaaactatt ttttttatta aggatggtga tgtttttgtt taagattgat
    78721 gattatataa tgtatggtat gacaggagtc tgcaaagtca tggatataac aaatgaacga
    78781 tttacaaatg gaataaaaaa agagtattat gtattgagtc ctatttattc taataataca
    78841 gtaataaaaa ttcctgtaga taatgaaaaa gtaccaatga gaaagttact ttctaaaatt
    78901 aatgtgcttt cattaataaa tgatattcct aatatggata catcatggat agataatgaa
    78961 aaattgagaa gtgagcaatt taaaaaaata ctcagaggtg gtaaatgtga agagttaata
    79021 aaattagtaa gaagtataga taataacaga gagtatgtaa aatctattgg taaaaaaaca
    79081 catcaagcag atgataatat aatgaaagaa gctgaaaggt tattaaatga agaatttgca
    79141 actattttag atatttctcc taatgaagtt agttcatata tttcaagtca tatacctcaa
    79201 taaagtgttt tagtatcctt tatttaatct attttaagta ttatttatgt atgctggttt
    79261 tggtaaaata aaatatataa ttaaattata taaaaaataa taatgattgt attgaagaat
    79321 tacagaatag tgcggagagc ctactccttt aggtgtgaga tggatatcac ttaaagattt
    79381 aaattgttat tgtagatgtt tttaatataa aacaagatta ataagtgtat tgtaagcttt
    79441 aagtgaaatt gatactataa tgagttactt agattttaaa atatataata ttataaaaaa
    79501 tccttttagg ttttgaatga ataagatgga tactatgttg aatagaatcc atcttattta
    79561 agttttattt atgttgttta tttgtaagca ttatttttgt acatgaaaac acagtgtaaa
    79621 aatatgctta gaattatgaa gttttattaa aaagatattc gacaaaataa gactaaaaat
    79681 attcttaaac ttataactaa gataaatatt gtatatttat agtgtagcct gaaaaattgt
    79741 gaatgtacga aatttattta gtattttatt gaaacaaagt agaagaagta ctatagttta
    79801 tctttgaata gattgttatt ttttagtgaa aaagttatta ggttaataca taaatataat
    79861 agcttataaa tagtttaagc atgttaaaaa agtagttatt agagatatat agttacattg
    79921 cttataagat acttaaaatg atagcattca cttatattta gaaaattaag ataaaaaatc
    79981 atttttatat agtaaagcat acct
//
LOCUS       DAMJXI010000011        77173 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.011, whole genome shotgun sequence.
ACCESSION   DAMJXI010000011 DAMJXI010000000
VERSION     DAMJXI010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 77173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77173
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.011"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            777..2447
                     /locus_tag="PC465_001031"
     CDS             777..2447
                     /locus_tag="PC465_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF and EAL domain-containing protein"
                     /protein_id="HDF2648356.1"
                     /translation="MREESNSLSLDHIEIFFELLSQSTEDYIFFWDINRNKFKISSAI
                     FDEFNLSKEIESDLVNCWSKIVYPDDVQIWKDDIQELLHGKKGEHNLEYRLINKYKEI
                     VWISCRGKVYVSDDPKTIFLVGRIKNIGEKNKFDSITGTWNREQFEHRMNYLIKEKIY
                     KNGAMFIMDIDNFKNINEKYGHSYGDKVLRAIATEVLEYLPKDVRLYRLDGDEFAFFY
                     PMCTKETIEKIYEKIQMYTNTQHEIESNKYYCTVTAGVAMYPEDGDNYLDLFKHVDIA
                     LDIAKISGKNRIKFFSQELYENKLKVISMQQKLRECVENNFNDFELFFQPQVNAVTKE
                     VIGAEVLLRWHSSTYGEVSPVEFIPILEQSNLIIPVGKWIIKEAVKQCKEWHKINPDF
                     KISVNVSYIQLKEDFFRDFIVECLVEYQLRPEFLILELTENCWIPDINLLNDKFISLK
                     GIGVYIAIDDFGTGYSSLNYLKELSVNIIKIERSFVKNITYNSYEYTFLEYIIKLAHI
                     INLKVCVEGIESYEEYDIVKSLGVDIIQGFLFGRPVSASEFYKFQLSK"
     gene            complement(2569..3303)
                     /gene="pflA"
                     /locus_tag="PC465_001032"
     CDS             complement(2569..3303)
                     /gene="pflA"
                     /locus_tag="PC465_001032"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HDF2648357.1"
                     /translation="MIKGKIHSIETFGTVDGPGIRYILFFQGCPLRCKYCHNRDTWDI
                     KSGKEYTVDEIITDALKYTSFMKFSGGGITASGGESTLQPEFLSELFKKAKENDIHTC
                     LDTSGFVDIETIDPVLDNTDLVLLDLKHMVEEKSIDLTGVGMDKALKLARHLESRNIP
                     VWIRHVLVPGITDDIDNLEKLGQFVATLKNVERFELLPYHSMGIHKWESLGIDYELKD
                     VPDATKEDVQKASEIISKFGVKVYNS"
     gene            complement(3463..5694)
                     /gene="pflB"
                     /locus_tag="PC465_001033"
     CDS             complement(3463..5694)
                     /gene="pflB"
                     /locus_tag="PC465_001033"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HDF2648358.1"
                     /translation="MNAWQGFKTGRWTKEINVREFIQLNYSPYEGNDSFLAGATENTK
                     KLWDEAMVLFKKERENGGTLDVDTKTVSGIAAYAPGYLDKELETIVGLQTDAPLKRAV
                     MPYGGIKMVENSCEAFGYELDPEIKDIFTKYRKTHNQGVFDVYTPEMRAARKSGIITG
                     LPDAYGRGRIIGDYRRVALYGVDALIEDKNEQKKSLEVSCMDEEVIRLREEITEQISA
                     LNELKKMAESYGFDISKPATNSKEAVQWLYFGYLGAVKDQNGAAMSLGRTSTFLDIYF
                     ERDLKAGIVTEEELQEYMDHFVMKLRMVKFLRTPDYNNLFSGDPTWVTECIGGMGIDG
                     RTLVTKNSFRMLNTLYTLGPSPEPNLTVLWSTKLPQGFKDFCSKVSIDTSSVQYENDD
                     LMRAYWGDDYGIACCVSAMRIGKQMQFFGARVNLAKTLLYAINGGVDEKSGVQVGPRF
                     EPITSEYLDYDEVMSKFEPFTDWLATLYVNTLNVIHYMHDKYSYEALEMALHDRDIFR
                     TMACGMAGLSVCADSLSAIKHAKVKTIRNEQGIAVDFEIEGDYPKYGNNDDRVDSIAV
                     ELVESFMNKIRKNKTYRNSYPTQSILTITSNVVYGKKTGNTPDGRRAGAPFAPGANPM
                     HGRDTNGALASLSSVAKLPYEHAQDGISNTFSIVPAALGKDMTERINNLSAMMDGYFA
                     QNAHHLNVNVFDRATLEDAMEHPEEYPQLTIRVSGYAVNFIKLTKEQQLDVINRTFHG
                     KMA"
     gene            5987..7048
                     /locus_tag="PC465_001034"
     CDS             5987..7048
                     /locus_tag="PC465_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HDF2648359.1"
                     /translation="MEKRKSIHLHKLNIYLIGGGDRLFITVVLFLVGFLLITKGADIF
                     INCTVEIGKKTNISEIILGATIVSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICN
                     TGLALGLVVFISPFNVDKKMFFSKSLLLIVSVIVLILLSLDGVITRGDSLLLIIILIF
                     YMVNNYRSVVGKSDTKNRNIKNNTSKDISTKKGKNYRGFSVLEIVKILLLFATGLIMM
                     IIGSQILIESGVIIASFLNIPQGIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNI
                     LGANILNIVSVIAVSAIPNNIPILSQNRQLDIPFMILLLLIVIIPTLKSNKLSRIQGI
                     LMLFTYFLYISILYFMYII"
     gene            7139..8752
                     /locus_tag="PC465_001035"
     CDS             7139..8752
                     /locus_tag="PC465_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2648360.1"
                     /translation="MNITKFEDLPISEGIKKAIAEMGFEEPSPIQAQSIPAILSGKDV
                     IGQAQTGTGKTAAFSIPILETIDPNNRSLQAVVLCPTRELAIQVSTEIRKLAKYSHGI
                     KTLPIYGGQPIDRQIKSLKSGVQVVIGTPGRTIDHINRKTLKMDNVKMIILDEADEML
                     DMGFREDIEMILSKIPEERQTTFFSATMPRGILELTKRYQKDPEHIKVVRKELTVSNT
                     KQYYIETRSSNKLEVLCRLVDVYDPKLSVVFCNTKRKADELVGDLQARGYFADALHGD
                     LKQTQRDIVMDKFRNGTIDILVATDVAARGIDVDDVECVFNYDLPQDEEYYVHRIGRT
                     GRAGREGMSFTFVFGKEMRKMKDIERYTKSKLIKHNIPTITDVEEKKVGTFFAQVKQT
                     IEEGHLTKQLQWLEGFCNDEDYAMVDIAAALVKLSLGEEMKEEIIEEKPRRERGDRKG
                     GTGAKDGMIRLFINIGRNQRVQAKDIVGAIAGEVGIPGKVVGTIDIYDKYTFVEIPKK
                     DAKTVIEKMKDIKIKGNKINIEKANKKKK"
     gene            9027..11012
                     /locus_tag="PC465_001036"
     CDS             9027..11012
                     /locus_tag="PC465_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDF2648361.1"
                     /translation="MSMTYMDPRVFLILEMVLEEDTNTLEQFSNVLGVSTRTIRNYIN
                     QINRELKGGIAKIVKNEKGTYSIRIEDESKLIEIVNFNRGKLSNFINLNSPDERINYV
                     LDILTMTNNPITIDDLAEEICIGRTTLIKDLKKADRILAEYDLELKRKPNIGMILVGE
                     EMDIRLLILDRLYENYIDVLENVNQINLVKDYDIECLRDELKKLFKKEELYITEQVLR
                     DVERYIIMSVLRNLNGYKFEKIDKRFEVIRCSDEYTLGLKLKDLLEKIFNIVLNEKET
                     IFLTMPLIGRKAPSTKLALSSIKINDSVKEVVDEVTSFLLETSGIDFKEDKKLIENLE
                     YHLYFALNRMRFNIRVKNPLLQEIKERYTFPYSVAKIAAMIIEEKFDLKICDHEIGYI
                     ALHFGSYFEKNSRKVLNVNRVAVVCGTGLGTAQLIRIKIGKILGESVEVNTFSDIEAK
                     ANLDLLKYYDLVFTTVDFKTDLDVPIFRVNALFNEESIKKEIENAILLKNSINLKSIK
                     KIEKNIPFIGKLIEEDKFFILNKSTFMENLEDMLEKLVHKGIIDIEFKKKVLKREKKS
                     STALDNYIALPHSVNTNGENLYLAFGILEKPVIWDTKEIRIIILMIIPDKNVDSTDLI
                     IKSYEEVLEVGRDKKMVEELAKAKSFDEFYKIITKRR"
     gene            11017..11451
                     /locus_tag="PC465_001037"
     CDS             11017..11451
                     /locus_tag="PC465_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HDF2648362.1"
                     /translation="MDPVIFIIASLITVYLLNIFLGYLQLKDFNKNYIELKRKGRVAI
                     GRKKGRISSGTIVLILINDDGVIVETRKMQGVTVLARVKSFEGLVGKSLEYIEKSDLT
                     VYNKLLKKAILDAVKQYITFEKNKCEDTNNLSTDEECRMEVV"
     gene            11480..12040
                     /gene="srlA"
                     /locus_tag="PC465_001038"
     CDS             11480..12040
                     /gene="srlA"
                     /locus_tag="PC465_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418408.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HDF2648363.1"
                     /translation="MTQFFQVLASGADSFMNLFRAGGQQFVGFVTDIVPLLVALLVTM
                     NAIINFIGTDRVERLAKKCSANIFTRYLILPVLGTFVFANPMTLSLGRFLPEKFKPSY
                     FAAASFSCHTMNGLFPHINPGELFIYLGIANGITTLGFSTADLAVRYLLVGIVANFIK
                     GVVTDYTTKFVEKQQGIALNSDIKIG"
     gene            12104..12472
                     /locus_tag="PC465_001039"
     CDS             12104..12472
                     /locus_tag="PC465_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sorbose transporter subunit IIB"
                     /protein_id="HDF2648364.1"
                     /translation="MAFNKVKIVKGSGGWGGPLIIEPTEKKNKVVYVTGGAKPETAVK
                     IAELTGCELIDGFSQGVKDDEIACVIINCGGTLRCGIYPQKKIPTINIMKTGKSGPLA
                     MFIKEDIYVSGVKPTNVEQL"
     gene            12497..13063
                     /locus_tag="PC465_001040"
     CDS             12497..13063
                     /locus_tag="PC465_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HDF2648365.1"
                     /translation="MAYDTKKKISEQSQGIVAKIGIALGNLTSTLFQAGRDTIDTLIH
                     TILPFMAFVAVLIGIINQSGIGNWVANLLTPLIGNVGGLVVLSIICSFPLLSPFLGPG
                     AVIAQIVGVLVGTEIGKGNIPPSLALPALFAINSQAACDFIPVGLGLAEAEPDTVQVG
                     VPSVLYSRFLTGAPTVLLAWLASFGLYK"
     gene            13104..13469
                     /locus_tag="PC465_001041"
     CDS             13104..13469
                     /locus_tag="PC465_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDF2648366.1"
                     /translation="MELIYSTQINKIGDNANEFLQHNMFVTFKDNAPQELENYCYIHS
                     ENNLVKEILTDDVLSINNVDYKITSVGELVNQNLSELGHITFKFTGEKDGAIGGTLYL
                     EEKEIAPIGVGTILKIIRK"
     gene            13570..14343
                     /gene="srlD"
                     /locus_tag="PC465_001042"
     CDS             13570..14343
                     /gene="srlD"
                     /locus_tag="PC465_001042"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HDF2648367.1"
                     /translation="MRKVALVVGGGRSLGEYLSKHLAKVGYDVAIADLNEDNAKKVAE
                     EIKTEFGCKSVGYSCNAIDERQVISTVKAIENDFDRIDLLVYNAGVAVSKKITDFGYK
                     DFKFIVDVNLNGYFLFAREVSKVMIAKGIEGRIIQINSKSGRVGSKHNSGYSAGKFAG
                     VGLTQSLALDLAEHKITVNALMLGNLLDSDMFESLIPQYAVKLGIPESEVKQVYIDKV
                     PLKRGCRFIDVANMLTFYASKEAEYCTGQSINITGGQVM"
     gene            14692..16836
                     /locus_tag="PC465_001043"
     CDS             14692..16836
                     /locus_tag="PC465_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2648368.1"
                     /translation="MDIIKKLSHGCTLDCHDCCKFNVYTKGNNVVKIEGDKNHPYTKG
                     FICKKGMAHLDRLNHKDRIKTPMLKVDGVWKEISFDKAIEIMAEKLTYYKEKYTSKSV
                     MHYDQYGSGSVLKYIGDIFFNFYGGVSRHKGGPCWSAGMHAQKYDFGVAKSHAIEDML
                     NSKSIFVWGKNPAYTTIHTMQIIKKAKEKGIKIVVIDPIYTKTAQIADKYVQVNPGTD
                     GALAIAMAKIIVEDKLYDEEYINSYVIGFEEYKKYLSSLELSFLIDECGVKENDIREL
                     VDLYTNKYSSINVGYGLQKYKNGGNTIRAIDALGAITGQIGFSGGGVNYANKVYPSVI
                     NSDPYNSQSYGEDREFYVSNISKFIEESLKNTSNKVNYASDELDMTSNKVNYVSDELD
                     ITSNKTDYISNELYNLSNKSIKDNIPIKMAVITKSNMLNQLPDLVELERVFSKIEFKV
                     CFDMFITDTATLCDMFIPCTNTLESEDIIYSSMTNPYITYNERAVKPAHKLMDEYYFF
                     MELAKKMGLNDYPFVEKRTYLEKVIEPLKRFDKNLDIEKLKNNYFTIHNPVAWEDKKF
                     ETPSGKYELYSESIKNLGISPTPVYISNKYKEIEDKNISFRLLTNHHADTLFSQHFMD
                     KKSIAQAYINRRMAKKVGIEDKDIVILRSKKAKINVQINIDDGVGNYIVKMYVGWWKK
                     HGNPNSLTDTGISDFGGQVTYNESMVEIIRQN"
     gene            16924..17259
                     /gene="spoIIAA"
                     /locus_tag="PC465_001044"
     CDS             16924..17259
                     /gene="spoIIAA"
                     /locus_tag="PC465_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor antagonist"
                     /protein_id="HDF2648369.1"
                     /translation="MVNYSLEHKNLYIEFMCSELDHHVANEIREEIDNLLSVNQVKNV
                     VFNFENINFMDSSGIGVIIGRYKKISNEGGRVSVINISSRVKKIFDLSGLNKIIGIYD
                     TYEEALSSL"
     gene            17273..17701
                     /locus_tag="PC465_001045"
     CDS             17273..17701
                     /locus_tag="PC465_001045"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor"
                     /protein_id="HDF2648370.1"
                     /translation="MNNIMEVKFSAISENESLARVIVASFAAKLDPTVDELVDIKTAV
                     SEAVTNAIIHGYEEDSSKFVFLRCEIEGNTIKIIVEDEGYGIENVEKAMEPLYTSKPE
                     LDRSGMGFTVMKSFMDDVEVSSVKDNGTRIEMTKKINVPK"
     gene            17724..18488
                     /gene="sigF"
                     /locus_tag="PC465_001046"
     CDS             17724..18488
                     /gene="sigF"
                     /locus_tag="PC465_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigF"
                     /protein_id="HDF2648371.1"
                     /translation="MEVTVAREEKKPLLSHEETLELIEKVQNGDEEAKEILISSNLGL
                     VRSVVSRFLNIGYDREDLFQLGSIGLIKSIYKFDPKFNVKFSTYAVPMILGEIKRYLR
                     DDGMIKVSRSLKQIAVKAKMESEALTKKLGREPSIEELAKAIDVEKEDLVMAMEANFN
                     VEYLQGVIHEEEGSPICLIDKISMKGESEEEKVVDNILLKDILGRLDKRERQIIVLRY
                     FEDMTQSEIGEMLNISQVQVSRIEKKVLSKLKEYIS"
     gene            18768..19205
                     /gene="spoVAC"
                     /locus_tag="PC465_001047"
     CDS             18768..19205
                     /gene="spoVAC"
                     /locus_tag="PC465_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AC"
                     /protein_id="HDF2648372.1"
                     /translation="MDKNYKKYVDQISPKPTYLKNYTLAFIVGGIICMIGQAINDLYM
                     KVGGLDKLGASSATSITLIFIGAFLTGLGVYDLIGKRAGAGSIIPITGFANSIVSPAM
                     EYKREGYVLGVGANLFKIAGPVLVYGIGSSILCGIIYYIFKMF"
     gene            19372..20385
                     /gene="spoVAD"
                     /locus_tag="PC465_001048"
     CDS             19372..20385
                     /gene="spoVAD"
                     /locus_tag="PC465_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AD"
                     /protein_id="HDF2648373.1"
                     /translation="MKNKRIGKRTVKLENKPTIISTGTIVGPKEGEGPLKDYFDMIMT
                     DDLYGEKTWELAESKMVETASQQAIQKAGKKLSDVNYMLGGDLINQIVPASFAARELA
                     IPFLGIYGACSTMAEGLCIGSMLIDGGFADLVLSGTSSHYCTAERQFRFPLELGNQKP
                     MTAQWTVTGAGSVLLAPNGDGPKVKYVTVGKVIDEGIDDGNNMGPAMAPAAIDTIYSY
                     FEDTNDDPNSFDIIATGDLGTLGKQIAEDFLKEKGVDISKVYTDCGIEMFNLKEQDVH
                     CGGSGCGCSATVFAGYIYDKLRKKEFNKVMLVSTGALLSPTSTLQKQTIPCVAHAVVI
                     VNE"
     gene            20399..20761
                     /gene="spoVAE"
                     /locus_tag="PC465_001049"
     CDS             20399..20761
                     /gene="spoVAE"
                     /locus_tag="PC465_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AE"
                     /protein_id="HDF2648374.1"
                     /translation="MLMDYVRVFIVGGIICLIAQVMMDYFKMQTPYVMVTYVTTGVVL
                     TFLGLYEPLVKFAAAGATVPIIGFGYSLATGVIKSIQSDGFLGIFLGGTTATAGGIAA
                     AIFFGYIMSVVFTPKAKP"
     gene            20944..21960
                     /locus_tag="PC465_001050"
     CDS             20944..21960
                     /locus_tag="PC465_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2648375.1"
                     /translation="MVTIKDIARNLGISYSTVSRCLNNNPNVSEKTKKKVVEEANRLG
                     FHFNVNARNLAKKETNRIGVIFSNNFNHQDTRKFFSDIMDSSINSIETNKYDFIIQPN
                     NNISGDSNVYKMVNGQMVDGLVIVSQSIKKEEYDFLKDNNFPHVFIYFKPSFIGEVDN
                     FFWDDNVYGGYIATKHLIDHGHKDIITVTSDDKSSKMHEDRTKGYLNAMEEANLKTEV
                     IKSKMDFESQVEFLEKYIDKIKKASAIFVQQDVPAISIIQELKTTYGINVPEDISIIG
                     YNNIELISYFRSHLSTIDDPREQVIKNGVDSLVNIINKKSTEHIPRKLYPRLIIRNSV
                     KRIK"
     gene            22335..23177
                     /locus_tag="PC465_001051"
     CDS             22335..23177
                     /locus_tag="PC465_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HDF2648376.1"
                     /translation="MKEKAGIRNAIIAAFIITILAELIGPISFKVMGINVTLLSILWA
                     IFIGMAVSPHLLGRVIPALKKFIGDNEINVSPYLLSLTLYPLGIMFGINAGPKVGILL
                     QAGPALLLQEFGHMGTMLIALPVGVALGLGRSALGGTFSLCRDTALGIIGDKYGLNSP
                     EGIGTLGTYISGSIFGTLLFSFLAPVGVLLGFHPYALAMASGMGSGSMMGAATASLMN
                     TVPQMSEQILAYSATSGLITAVTGIYIELFLSLPVANYYYSKVAPVIERFRGRKTRRT
                     SNKL"
     gene            23192..23656
                     /locus_tag="PC465_001052"
     CDS             23192..23656
                     /locus_tag="PC465_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648377.1"
                     /translation="MEKTFKTIMEQIKIVLFIYIIICFGQMIALKTQAQDLLIGSVSG
                     FLLVIIAIIIKNFVKKPNLPGFAWATLVAFVLSLPISPVGDIIATNVGKINFMSTVTP
                     LLAFAGISVGNQLDILKTLSWKLVVISFIVMTSTYFGSAFISQTVLRLNGML"
     gene            23643..24815
                     /locus_tag="PC465_001053"
     CDS             23643..24815
                     /locus_tag="PC465_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2648378.1"
                     /translation="MECFKEVVNMNELKAKIKEEIKLLSEEKKTSFEKVSDYLFSNPE
                     LAFEEYKSQKALCDLLEENEFNVTKGVGGLETSFEAVYSNGTNGKTVAFLAEYDALPG
                     MGHACGHNIIGTSSVGAGIILKEIMKKHNIEGTVKVFGTPAEERVGGKITMIKEGVFN
                     NVDAALILHPSDASMPDDISFAQVNLKFDFTGKASHAAAFPWEGKSALSGVIALFNSV
                     NSMRLHLKDYARVHGIITDGGSIHNIIPEKSTAIFNVRALSIEYLNEICEMLKNCAKG
                     AAISTGTNVEIVQLDEIYKEIKNDSELVNIVRQNFEVLGEDYVERDLSQGIGSTDTGN
                     LTHEIPAIQAYIKLKENTATHTDEFAVAAGGEEGKVALIKAIKVLAMCGVDILYSK"
     gene            24859..25794
                     /locus_tag="PC465_001054"
     CDS             24859..25794
                     /locus_tag="PC465_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1177 domain-containing protein"
                     /protein_id="HDF2648379.1"
                     /translation="MILKQVIEVYDILDKANANGEEVKTYLQGYGEVDVTVKELSSSK
                     GSTDLVKLTIPGKNGKLKGGDAPTLGILGRLGGIGARPEVIGFVSDGDGALVAIAVAA
                     KLLDMQRKGDILDGDVVISTHICPDAPTKEHYPTPFMDSPIDMMTMNENEVDSSCDAI
                     LSIDTTKGNRVINTRGFAISPTVKEGYILKTSDNLLDIMQTVTGKSPFVFPLSIQDIT
                     PYGNNLYHLNSILQPAVATDAPIVGVAITTEMPVAGCATGATNFSDLDSAGRFAIEVA
                     KLFGRNKCDFYDKEEWEMLIKRYGKLNRFQTFGIQ"
     gene            complement(26069..28762)
                     /locus_tag="PC465_001055"
     CDS             complement(26069..28762)
                     /locus_tag="PC465_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HDF2648380.1"
                     /translation="MNNDNDKNGNKIRRKKVSSSGNTNKPINRTSANKTRSTKNKKKS
                     KKSDKFKKLRVFGIVFLVLLVVGTAGTAGLVFASLRDVTPVTEAVLDKQTNQTTTIKY
                     ANGKTLSTAPSVNKKTPVPLDKISPYLQHAVIAIEDERFYEHKGVDIKGLFRSVLKTL
                     TGTKQGGSTIPMQVSKMLLTTEQQTIPRKIKDIYYAHEMSKTVSKDKILETYLNNFFV
                     GRGLAGAEAGARGYFDKSAADLTLAESALLAGSTKNPSRFSAYKTSKLEGNETKEDLE
                     NKLLFFVNTTDDDLDDPTQVDFDMIEKIKSWELISNDTYRQLKAGTLVVRKAVSNPEA
                     KKRQEIVLKKMLELKYIKQSEYDEAIKAKIEIKLPQSSDKVSSSVEDLIESEVINALM
                     EQGHTNDEAQNLFYNGGLIVNTTIDPKMQDALEEEFDRNSNFPGHMVGPDGVSQPQAA
                     MVILDYKNGEIRALAGGRNISGRKTLNRATNPHQPGSSIKPLAIYTPAIDTLKITQAT
                     ALSDSRGGYKFEENNKWNPRTTTAGHGSMSLRKALAKSSNTIAVKTAGMLGDSYDECV
                     DIMMDYLKNFGITTLKNNHSGSSEASDRIFPSLTLGGMANGITPLQMAAAYGTLANHG
                     IYVEPSIFTTITTFDGQLLVKNAPEEHKVVEPEVAYVVTDMLESVITEGTGGVAALPK
                     GMPVAGKTGTTNIAYDAWFVGYTPYYVGATYIGDDAGRKDDSGNTIKRREVPHGSTST
                     AKLWEKIMEKIHANLTVTEFEVPKNVYFTKINLEDGGKQSSGSKAAFIEGTAPTKVSS
                     QPSSEDTKKPDNNQPEENNNNNNNTGDNGGGSTPPDNGGNNGGGSTTPPDNGGNNGGG
                     GSTPPDNGGNNGGGSTTPPDGGGNNGGGSTTPPDGGGTPAT"
     gene            28976..29674
                     /gene="yunB"
                     /locus_tag="PC465_001056"
     CDS             28976..29674
                     /gene="yunB"
                     /locus_tag="PC465_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YunB"
                     /protein_id="HDF2648381.1"
                     /translation="MNRIVDRKTKNEFRKIIAIFLVILFLSVFIGSFIYIDKTLRPTI
                     TVLAETKALELANRSINKAVAEMVEGKINYEDLMDIQLDNNGKITMIQANTIMMNEIA
                     SAIALEIQDELKKDKTASSYIPIGTALGSPILAKYGPKLEVSIEPIGTVSVNFKTEFE
                     SSGINQTRHRIYLEAQTQVKVVIPLITSTKQIKAQIPICETIIVGDVPESYVNIPEKN
                     LGNVLPNTGKNTNK"
     gene            complement(29886..30893)
                     /locus_tag="PC465_001057"
     CDS             complement(29886..30893)
                     /locus_tag="PC465_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HDF2648382.1"
                     /translation="MQLKNFHFKNNTLSKKTNLAKSKFTIVLTFLFLLYFFSNNLIYA
                     QNLQKNEPEYLIPIGNVLQIDAELKNIIVRNPGEASPFRLGDAIVKVNNAEVDGYSDF
                     ANTLNALPEEKQVSILLNRGGQLITMKTTKHILEKISFNNLLSGFATLTYINPDTSEF
                     GAVGHPISVGNARKIPIKTGSISTTKHLNIEKSYKGSVGCINAKRENIIGSFTENTDF
                     GIRGQINNFDISKLKKYKVASLDEVKLGKAQIILQDNFNKCKKYNIEIIDIENQKHPE
                     SKSFKIKITDKKLLAQTGGIVQGMSGTPIVQDNKIIGAVSHAIENDPAVGYGVFIKWM
                     L"
     gene            31121..32005
                     /locus_tag="PC465_001058"
     CDS             31121..32005
                     /locus_tag="PC465_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2648383.1"
                     /translation="MKKYRLLVTCIIAMGIIIIGTSNPVSNFYKTTNLISSGNITNEK
                     ADKDENSNKNNKDKNEDKSNSKSNKDKSSEDKSSDNKNEIQKNKKLLICIDPGHQGKG
                     DSNLEPVAPGSSSKKARVSSGTEGIATKKPEYVLNLEASLVLKSILESKGYNVIMTRE
                     THDVNISNSERAILANDKKADMVVRIHADSLNNSSKTGASILIPEKDGKYTAPIYEES
                     NKCAEFIKQNMEQSGIQINGIVQRGDLTGFNWSKVPAVLVEMGFMSNYNEDQMMSNPD
                     YQRKMMQCIADGLDAYFK"
     gene            32207..33757
                     /locus_tag="PC465_001059"
     CDS             32207..33757
                     /locus_tag="PC465_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2648384.1"
                     /translation="MLVVENVSHGFGARTILENVSFRLRKGEHIALVGANGEGKSSFL
                     NIITKKLMPDAGNIKWSSRATVGYLDQHTVLSKGKTIREVLREAFKHMFDLEQEMIAM
                     YDKMGEASDDEMSKLLEETAEIQTILENSGFYMIDAKIQEVANGLGLGEIGLDKDVTD
                     LSGGQRTKVLLTKLLLENPTILILDEPTNYLDEEHITWLTKYLQEYENSFVLVSHDIE
                     FINNTCNVIYHMENGELNRYKGNYDEFVRLNDIKKRQEEQAYDKQVEERKRLEDFVAR
                     NKARVATRGMANSRQKQLDKMEILERPKEKIKPTFAFKDARAASKIIFETEDLVLGYD
                     EALTKPLNFHLERGKKIALKGMNGIGKSTLLKTLLGIIKPFEGNVKLGDYLEVGYFEQ
                     ESSRENSNTPMDEVWSEFPGLTNFEVRQALAKCGLTNEHITSQMRVLSGGEAAKVRLC
                     KVMLKNINFLVLDEPTNHLDVEAKDELKKAIKEFKGTVLLVCHEPEFYSEIVDDVWNI
                     EDFTTKIV"
     gene            33786..34433
                     /locus_tag="PC465_001060"
     CDS             33786..34433
                     /locus_tag="PC465_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HDF2648385.1"
                     /translation="MKKFLNVLFSICISIVIIVGVINFTVGFKQLYYFDIDYLNISEL
                     SGLSKDDIKLNYDYLIDYNLNKNVSEFKLPTLKSSPQGKIHFEEVRNIFQNINKLAKL
                     LLVVSLVGIILSVKNKNIKILKTTSITLIIMPLLLTVPILLNFEKSFIIFHKLLFRND
                     YWIFNPDLDPVINILPEEFFFHSGMMILILILLVSIVLFVMYKLCKSLSIKIFQC"
     gene            complement(34575..34835)
                     /locus_tag="PC465_001061"
     CDS             complement(34575..34835)
                     /locus_tag="PC465_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich small domain-containing protein"
                     /protein_id="HDF2648386.1"
                     /translation="MGENYKFFNHKDCEFFPCHKTNKPEEFNCLFCYCPLYALGENCG
                     GNFKYTDKGIKDCSSCILPHKKDNYNYIMSKFQDLVKITSKK"
     gene            35052..36335
                     /gene="hflX"
                     /locus_tag="PC465_001062"
     CDS             35052..36335
                     /gene="hflX"
                     /locus_tag="PC465_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDF2648387.1"
                     /translation="MKEIQEKALLVGLNLTTIVKKNDDIDTNESMEELKELTKAAGAE
                     VVGSLIQNKHSVDAAYYIGKGKVEEIRAYSDSLDATLVIFNDELSGAQIRNIENVVGR
                     KVIDRTTLILDIFAQRALSKEGKLQVELAQLKYRLPRLYGMGGEMSRTGAGIGTRGPG
                     EQKLEIDKRHILNKAADIRRELKEVKKNRETQRVKRLKSNIPIVALVGYTNAGKSTLL
                     NELIKTHKDYEQEKEVFVKDMLFATLDVTLRKALLPNKKEFLVVDTVGFVSKLPHDLV
                     EAFKATLEEVQYADLILHVIDATNTSYELQKSTTEGVLKELGVNDKKHILVYNKVDKL
                     ELDIYPKSQEDIVYISAKQGINMDKLLNMIEIALMENTYSVSLMLPYERGDIFSRIKD
                     KYNVENFEYGESGITLDVDLDEEDFNIYREYILEK"
     gene            36343..37020
                     /locus_tag="PC465_001063"
     CDS             36343..37020
                     /locus_tag="PC465_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HDF2648388.1"
                     /translation="MDINWENIDNLEDYFITYLLYKESKTVSQISKIRNISSTEASEQ
                     LIQAKLKIKEMQKDDFEASKDILDKFLELDKIKRLDFMDSLDDEKMVYFKRKVFKRIL
                     VEKNAEDLIVLIWATGELKDDRFLKLLHQLTNHRHSDIRRITYSAIRKIESPSSREVL
                     QKGLYDKNAQTRQYCAKALSKLGDENSLKILQQLKDKNKNFEKEYVLRAYDEAIKSLE
                     NAKNLKK"
     gene            37106..37549
                     /locus_tag="PC465_001064"
     CDS             37106..37549
                     /locus_tag="PC465_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF2648389.1"
                     /translation="MIVRRCAGGVVFYANKVLIVKNDRGEWTLPKGKILGGGLPYESA
                     VQRVKVETGIDAKMIDVAGDTMYEFFSRSRQQEVCNAIMWYVMEACNTDCVLAPEFQE
                     GGFYKVKDALEMLSHHKEQALVEVSYKKFKELKKLVSEGDDVPAN"
     gene            37854..38498
                     /locus_tag="PC465_001065"
     CDS             37854..38498
                     /locus_tag="PC465_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HDF2648390.1"
                     /translation="MSNYRTLHEFGTDEITIEKSVFIGYAKPIKSEEEALEFINEIKK
                     KHKDATHNVWAYTVGKNMNIQRYSDDGEPQGTAGIPTLEVIKKEDLRDVAVVVTRYFG
                     GTKLGAGGLVRAYTKGAKLGLEAGKIIYKVMYQEVKVKIDYTQLGKVQNELMNLGYFI
                     KDTVYEDNVEIVVYSRLEDVEKLSEKMIDITSGTGKIVLGEEFYLSEQNGEILI"
     gene            complement(38584..38961)
                     /locus_tag="PC465_001066"
     CDS             complement(38584..38961)
                     /locus_tag="PC465_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDF2648391.1"
                     /translation="MLFALIGFFAGIIGGMGMGGGTILIPALVLLAGIDTKIAQSVNL
                     LSSIPMTLIALAIHIKNKNVIFKLVIPIAVFGVLGAVFGSLLANYLSSDILKKIFGIF
                     LLLVGLFEVKKGFCAKSDKKPLN"
     gene            complement(38961..39347)
                     /locus_tag="PC465_001067"
     CDS             complement(38961..39347)
                     /locus_tag="PC465_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDF2648392.1"
                     /translation="MKKTDDLKQKYFDFNLKNTIIGVFTGFINGVFGSGGGTLLVPIL
                     NDIVKVEEHKSHATALSIIIFLTTASSVLYVSKGTYDVNLTIKVAVGSILGGIIGAKL
                     LNKVTGKFLRISFGIIMIIAALRMVF"
     gene            39526..40281
                     /gene="nadE"
                     /locus_tag="PC465_001068"
     CDS             39526..40281
                     /gene="nadE"
                     /locus_tag="PC465_001068"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HDF2648393.1"
                     /translation="MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLI
                     KKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKD
                     KHLYREEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGV
                     DILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEG
                     RLDEVPKRDQEIIERLHRLSEHKRKTPAQPPKF"
     gene            40364..41083
                     /locus_tag="PC465_001069"
     CDS             40364..41083
                     /locus_tag="PC465_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2648394.1"
                     /translation="MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKEGGADPEYNA
                     ALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDN
                     KNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAE
                     DFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNK
                     LVDMLEEDDDVQDIYHNWEVE"
     gene            complement(41250..42254)
                     /locus_tag="PC465_001070"
     CDS             complement(41250..42254)
                     /locus_tag="PC465_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDF2648395.1"
                     /translation="MATIKDIAKDCGLSSATVSYVLSGKGNERRIPLHTQELILNSAD
                     KLGYKRSTPIKHNNIKIAFYWQDEGFELASTNILQAINHIISLEHLNINIIIRPYKVG
                     HLCDDEYFFANNYYDGIVLTGINADDIEYLVKNKPKIPVVVVNREIPGFSSVSIDNEE
                     TGRIAALHAIQNGKNDIAVVFNPTSFTCMTLRGKSFLKTCKEHGIHLSDSIYYCSNKI
                     DSGYDIAQKMLAKNSLKKVIFCNHDVVALGMMNAFHESGIVIGEDIQIFAASNGPSRL
                     MARSIPPLTVIDLKMEETAERSLRMIIDTVTGRINGIQQQVIYPSIIYRQSSPAQNLL
                     "
     gene            42521..43417
                     /locus_tag="PC465_001071"
     CDS             42521..43417
                     /locus_tag="PC465_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="HDF2648396.1"
                     /translation="MSKVNIFEVGPRDGFQNLKEFLETDKKLKIIDGLIASGIKQLEI
                     SSFVSPKAIPQMKDAKEVATYCVEKYPDVKLYALVPNLYGAKVAWECGIRDISYVISL
                     SETHNKKNINRTHEESIDELKKIMNTYPDMNICIGMATVFGCPFEGLPKIEDAIRFAK
                     RLWENGIREINLADTIGIADPKQVRETISALVEALPECRWQVHIHDTRNMGMVNTLVA
                     IESGITTVQSTLGGLGGCPFAPGASGNTATEDLVYMLERMGYDTGVDFVKLLELSKYQ
                     KSFVNGVYSGHHINIKSDSCNC"
     gene            43555..44817
                     /locus_tag="PC465_001072"
     CDS             43555..44817
                     /locus_tag="PC465_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648397.1"
                     /translation="MDIIALLLFLGVIIIAFVRKNNAGILALAIGVIAVRIFGMDDKE
                     LYGAISNSMFTTLVGITLLFAIVNSTGALKLVAEKIVAASGKRVWLIPIAVFIAGFVV
                     AGVGPGAIPALAIIPAMAVPVAITVGYNPVMLALIGECGLMAGRMTPITPEGQIITTV
                     AEGVGIENVMPTILACQTLSTIVFSIVLFIIFKGYKLKKPINVIDSKQIEKFNIKQII
                     SLISIVVMIAFIIIFDMNVGLAAFAVSAVLIFFNIADEGECIKSIPWSTIVMVLGVGA
                     MMTIVDAAGGIDLMSNALSSLMNSKTATPIMSISAGLMSMVSSALAVVYPTMMPMCVD
                     IAKAVGGVDPLALIAAVGVGGSLAGVSPLSTGGALILAAMGSSKKDFNKEEQNKVFVQ
                     LFIMSAVGLLVIAVVSILSFNAITHLMN"
     gene            44893..46086
                     /locus_tag="PC465_001073"
     CDS             44893..46086
                     /locus_tag="PC465_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HDF2648398.1"
                     /translation="MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGD
                     DTRGFGPFVNGESLYYANINRNKKGITLNLKSEEGKNIFLEMVKHADVVVENYRPGVM
                     EKLGLGYDELAKVNNQIIYGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEP
                     TRVGNAMGDVLGGMNLTIGILTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDS
                     GQPELMGNRYASAYPYDSFKASDGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTN
                     LNRCEHYKALKPEIEKWSVKHTIKEAVDLISEAGVPAAPIYNLDCVTTDEHIAKAREM
                     IVDISHPIIGNMKVNGNPVKLMTTKAKIDMPAPSLGESNEEIYNGWLGFDSDKIKDLK
                     ENGVI"
     gene            46715..47509
                     /locus_tag="PC465_001074"
     CDS             46715..47509
                     /locus_tag="PC465_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HDF2648399.1"
                     /translation="MESVMENLNNLKVELKDKVCVITINRPKALNALNSDTLRELSQV
                     IDVVSENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGIFDKIEALEK
                     TVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTG
                     IAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESMKMMNQIVEKAPIAIRYAKVVI
                     NKGIDMDLKNALELEKDIAGLTFATRDKQEGMNAFIEKRKPVFENK"
     gene            47604..48944
                     /locus_tag="PC465_001075"
     CDS             47604..48944
                     /locus_tag="PC465_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF2648400.1"
                     /translation="MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITG
                     SLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDK
                     ALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMV
                     APGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFIVGSTILYKMVSKEKANGGHFIA
                     HESDIFDEAEATNSKRENGPNGVIALIPLIVSILIINVKVNGKAIVPIEVGVFIGALL
                     VYLLLNKYQDNTKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNI
                     PGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAAL
                     DSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP"
     gene            49081..50313
                     /locus_tag="PC465_001076"
     CDS             49081..50313
                     /locus_tag="PC465_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HDF2648401.1"
                     /translation="MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDP
                     GRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSETGIEIMDKLLSEANVFVSSYR
                     TGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAE
                     KDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLA
                     STQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEE
                     KFASSVESKKNATELISILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAI
                     ANNYIYEHTSKNGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIE
                     ALIESGIVTMNKEECEIC"
     gene            50353..51495
                     /locus_tag="PC465_001077"
     CDS             50353..51495
                     /locus_tag="PC465_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HDF2648402.1"
                     /translation="MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSK
                     MAKIGFNGIGTPVEYSGSGGADIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGT
                     EEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
                     GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNC
                     RVPKSNLLGKEGKGFNIAMTCLDGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPI
                     SALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASRTAREVTNL
                     ALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG"
     gene            51506..52300
                     /locus_tag="PC465_001078"
     CDS             51506..52300
                     /locus_tag="PC465_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF2648403.1"
                     /translation="MNIVVCLKQVPDTNEVKINKETGTLIRDGVPSIINPDDRNALEE
                     ALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIA
                     AAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVQDDKLLVTRYT
                     ETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKITVLTLADLDVDTTQI
                     GLKGSPTNVYKSFVPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV"
     gene            52311..53333
                     /locus_tag="PC465_001079"
     CDS             52311..53333
                     /locus_tag="PC465_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDF2648404.1"
                     /translation="MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLA
                     DQLGKELAVVIAGYEVEKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERK
                     KPEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMAT
                     IVCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSV
                     NLTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGT
                     TVRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICDYGIVGDLYEIIPEM
                     IESLNR"
     gene            53432..54808
                     /locus_tag="PC465_001080"
     CDS             53432..54808
                     /locus_tag="PC465_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HDF2648405.1"
                     /translation="MKEQWYKDIFARVLSMTDDGFIVVNTSGVIIDINDKYCDFLGKE
                     RKDIIGQNIQSIIPNTKMLDVMKNKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGE
                     VVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
                     VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGY
                     DEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKT
                     IKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILN
                     KLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMD
                     NISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIK
                     KYEIELNN"
     gene            complement(55140..55484)
                     /locus_tag="PC465_001081"
     CDS             complement(55140..55484)
                     /locus_tag="PC465_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648406.1"
                     /translation="MDQIKRLHELQQKSYLTKEEFEELKNNTYIERFELRDECDNSYI
                     YTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSC
                     GKELDKEVENYD"
     gene            55972..56982
                     /locus_tag="PC465_001082"
     CDS             55972..56982
                     /locus_tag="PC465_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HDF2648407.1"
                     /translation="MHEDKNDIFESIDTEDFDNKTEEECLELVRKNGLNLIYIKNQTE
                     EICLEAVRQNCNAIKCVQNQTEKICIEAVKQDWRMLEFVEEPTEEICMLAINQDGTAL
                     KYIENQTEELCLRAVEKNGAALEYVKEQTEEICIEAVRNSEFGLARVKNQTEKICMEA
                     VKHCSYNLKWVENQTEEICMEAVRQNGLDLKFVKNQTETICLRAVRQNGMALEFVKEQ
                     TVGICLKAVRQYGMALKFVKEQTEEICTEAIKQDKRALSFVKGDKEKYKALYDNNEPF
                     AKRYVRNVIEKENRALIKKGEENAKIKIAGKLYDRGMSFEDISDIVEIEISKLKVSLG
                     VF"
     gene            57118..57606
                     /locus_tag="PC465_001083"
     CDS             57118..57606
                     /locus_tag="PC465_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2648408.1"
                     /translation="MKITVLYQTRSGNTERVAKLIEDGAKKVDGVDVKLMRLDNIDLD
                     YLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAI
                     LTIVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKEL
                     FA"
     gene            57782..59710
                     /locus_tag="PC465_001084"
     CDS             57782..59710
                     /locus_tag="PC465_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2648409.1"
                     /translation="MVWHIEYEIFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSF
                     LFIISNILGSFCLNNIDKIPIFITFLLNQIYLLLLPIPAALVSFYVMAIIYQDIRYMK
                     KRLLFLSIPLIICIILSITNPFTHILFGLSKETGYIRGCGYVATFASFFFYAIYSAFL
                     SFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRG
                     LIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALEEV
                     GKYLIQIHDVNHVYRIGGDIFSIVVNSQLGIEPDDIIRKIEERFKKPWLVEEISFNLA
                     TSIAVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKKKHVIKNCL
                     KEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFIPIAEQTGLINS
                     IGLVVFEKVCRFIASDEFEDLKLDNIAVNLSVVQCMQKNLADDLLYLMNKYNVSPTKF
                     KLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIAYSGVTNMLSLPFSVIKLDKS
                     LIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSK
                     PVPEDVFKNLLKENTFTS"
     gene            59887..60297
                     /locus_tag="PC465_001085"
     CDS             59887..60297
                     /locus_tag="PC465_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDF2648410.1"
                     /translation="MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVF
                     IDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFI
                     VMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE"
     gene            60319..60621
                     /locus_tag="PC465_001086"
     CDS             60319..60621
                     /locus_tag="PC465_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HDF2648411.1"
                     /translation="MNKKIVAVCESERSLNSLKTAANDLGFDLVYEIQENDNIKNELS
                     IYDIEDASIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN"
     gene            complement(60838..61530)
                     /locus_tag="PC465_001087"
     CDS             complement(60838..61530)
                     /locus_tag="PC465_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDF2648412.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIEELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMMAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(61556..62743)
                     /locus_tag="PC465_001088"
     CDS             complement(61556..62743)
                     /locus_tag="PC465_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2648413.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRLPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSIFYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            63079..64956
                     /locus_tag="PC465_001089"
     CDS             63079..64956
                     /locus_tag="PC465_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2648414.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKKVYDEVIKIVPQSNNVGKKNESQENQGIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEIIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSSIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKAGYDVTTPVIVNNTFDFGQVVSCKSSYVSTNDNIISLVLAG
                     N"
     gene            65266..66672
                     /locus_tag="PC465_001090"
     CDS             65266..66672
                     /locus_tag="PC465_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF2648415.1"
                     /translation="MNTGFPKDFLLGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLEFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHSFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEILDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            66700..67548
                     /locus_tag="PC465_001091"
     CDS             66700..67548
                     /locus_tag="PC465_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2648416.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            68209..68901
                     /locus_tag="PC465_001092"
     CDS             68209..68901
                     /locus_tag="PC465_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2648417.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            68898..69833
                     /locus_tag="PC465_001093"
     CDS             68898..69833
                     /locus_tag="PC465_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2648418.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIYKRLKDIEEIL
                     ADVQIGDENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQVSVESEIGKYTVFTVSLPLI"
     gene            69981..70904
                     /locus_tag="PC465_001094"
     CDS             69981..70904
                     /locus_tag="PC465_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2648419.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            70888..71658
                     /locus_tag="PC465_001095"
     CDS             70888..71658
                     /locus_tag="PC465_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2648420.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVPKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPILSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            71668..72450
                     /locus_tag="PC465_001096"
     CDS             71668..72450
                     /locus_tag="PC465_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2648421.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVTLVVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            72827..73363
                     /locus_tag="PC465_001097"
     CDS             72827..73363
                     /locus_tag="PC465_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HDF2648422.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            73395..73784
                     /locus_tag="PC465_001098"
     CDS             73395..73784
                     /locus_tag="PC465_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDF2648423.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            73821..74207
                     /locus_tag="PC465_001099"
     CDS             73821..74207
                     /locus_tag="PC465_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HDF2648424.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            74334..75776
                     /locus_tag="PC465_001100"
     CDS             74334..75776
                     /locus_tag="PC465_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF2648425.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVEDESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            76073..76888
                     /locus_tag="PC465_001101"
     CDS             76073..76888
                     /locus_tag="PC465_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2648426.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINDFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKKVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEMRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
BASE COUNT        29018 a         9100 c        13898 g        25157 t
ORIGIN      
        1 aattttgtag tgtaatcgta ttttttatta attcttacaa aatcaatgaa aataagtata
       61 tccattttaa agtacataaa tttaaaaatc cagaaaaata tacttaaatt atgtaagtaa
      121 aagaggggtt gaatcagttg aaaatgtaat attagtaaat agtacatcaa tcctatatac
      181 cctgtaagca actctatttt catgtactaa aaatgtacct attttattaa ctgaaaagaa
      241 taaattaaat gtaagtacat aagaagatag aaaaaattaa aaacaaaaaa tatttatata
      301 aataaatata aaaaatgata taatccctat taaaaaattt atagatgatg aagaaatatc
      361 aaaatcttat attataggaa gagacacttc tttgccaaaa tctatagaaa aacaatacca
      421 aatccaaaga gaataggcgg agaaaaaaat aaaataaatt caagagtaat agaaaagttt
      481 tatagaataa agaactgata actctttata taacgaaaaa tagaatttta agagaaaatg
      541 atttaataaa tgatttaaca tggtgtttta gcaggtaaaa ataaatcacc agtaatgatt
      601 atagaaaaat tactttatga atctcaaaaa acttagttaa gagtaagaga tttgataaga
      661 taactaaagt tggggaaatg tgtttgatga gacaaaaaat tagtaaaata gtataatcta
      721 gataaggata ttttgttgat taaactacac taatagtaat attgtagggg gaaaagatga
      781 gagaagaatc gaactcttta agtttagacc atatagaaat tttctttgaa cttttatctc
      841 aaagtacaga agattatata tttttttggg atataaatag gaataaattt aaaatttctt
      901 cagcaatttt tgatgaattt aacttaagta aagagataga atctgattta gtcaattgtt
      961 ggagtaaaat tgtttatccg gatgatgttc aaatatggaa agatgatata caagaattac
     1021 tacatggaaa aaaaggtgag cacaatttag aatataggtt gattaataaa tataaagaaa
     1081 tagtatggat ttcttgtaga ggtaaagttt atgtgtcgga tgacccaaaa actatatttc
     1141 tagttgggag aataaagaat attggtgaaa aaaataaatt tgattctatc acaggaacgt
     1201 ggaatagaga acaatttgaa catagaatga attatcttat aaaagagaaa atttataaaa
     1261 atggtgctat gtttattatg gatattgata attttaaaaa tataaatgaa aaatatggac
     1321 attcttatgg tgacaaagta ttgcgtgcaa ttgctactga agtattagaa tatcttccaa
     1381 aagatgtaag attgtatagg ttagatggag atgaatttgc atttttttac cctatgtgta
     1441 ctaaagaaac tatagagaaa atatatgaaa agatacagat gtatacaaat actcagcatg
     1501 aaattgaatc aaataagtac tattgcacag tgactgcagg cgttgctatg tatccagaag
     1561 atggagataa ttatttagat ttatttaaac atgttgatat tgcattggat atagcaaaaa
     1621 ttagtggtaa aaatagaatt aagttttttt cacaagagct ctatgaaaat aaactaaagg
     1681 taatttcaat gcaacaaaaa ctaagagagt gcgttgaaaa taattttaat gactttgagc
     1741 tgttttttca accccaggta aatgctgtta caaaagaggt aataggggca gaggtacttt
     1801 taagatggca ttcgagtact tatggagaag tatctcctgt tgaatttata ccaatactag
     1861 aacagagtaa tttaattata ccagttggga agtggattat aaaagaagct gtaaaacagt
     1921 gtaaagaatg gcataaaata aatccagact ttaaaatatc tgtaaatgta tcgtatattc
     1981 agttaaagga agattttttt agagatttta tagtagaatg tttagtagag tatcaattaa
     2041 gacctgaatt tttaattttg gaattaacag agaattgttg gataccagat ataaatttac
     2101 taaatgataa atttattagt ttaaagggta taggagtata tattgcgata gatgactttg
     2161 gtacaggata ttcatcttta aattacctta aagaactgtc tgttaatata ataaaaattg
     2221 aaagaagttt tgttaagaat attacatata atagttatga atatactttt cttgaatata
     2281 tcattaaatt agctcatatt ataaatttaa aagtttgtgt tgagggaata gagtcttatg
     2341 aagagtatga tatagtaaaa agcttaggtg tagatattat tcagggtttt ttatttggaa
     2401 gacctgtaag tgcctctgaa ttttataaat ttcagctatc aaagtgatgt atataaaatg
     2461 agatatatag tatataaaaa tagggcaaag tggaagtttt gaagtttatt aaaaatttac
     2521 actttaccct attttgttat gtcttctata aaggattaat atactacact aactattata
     2581 tactttcact ccaaatttag agattatttc actagctttt tggacatctt ccttagtggc
     2641 atcaggaaca tcttttagtt cataatcgat acctaaactt tcccatttgt gtattcccat
     2701 agaatggtat ggtagcaatt caaatctttc tacatttttc aatgtagcta caaattgacc
     2761 tagtttttct aaattatcta tatcatcagt aatgccagga actaaaacat gtcttatcca
     2821 tacaggaata tttcttgatt ctaagtgtct agcaagtttt aatgccttat ccataccaac
     2881 accagtcaaa tcaatagatt tttcctcaac catatgtttt aaatcaagta aaaccaaatc
     2941 agtattatct aaaactgggt ctatagtttc tatatctaca aatccagatg tatccaagca
     3001 agtgtgtata tcattttctt ttgctttttt aaataattca cttaaaaatt ctggttgaag
     3061 agtggattca ccaccagagg cagttatacc tccaccagaa aacttcataa aagaagtata
     3121 cttaagagca tccgttatta tttcatcaac tgtgtattct tttcctgatt taatatccca
     3181 tgtatccctg ttatgacagt atttgcatct aagaggacac ccctgaaaaa ataatatata
     3241 tcttattcct ggtccatcta cagtaccaaa cgtttctata gaatgtatct ttcccttaat
     3301 catagagttc acctcacaat atattttaat aaccttatca atagttataa tatttctcta
     3361 aaaaaggcca tcttatacca gaaataattc aaatataaga tagcctttta tttttatttt
     3421 ttacacagta gtaatcttag ttaaagtata aaaatttaaa gactaagcca ttttaccgtg
     3481 gaatgttctg tttataacat ctaattgttg ctctttagtt aattttatga agttaactgc
     3541 atatccagat actcttatag ttaattgtgg atattcttct ggatgttcca tagcatcttc
     3601 taaagtagct ctatcaaata catttacatt taagtgatga gcattttgag cgaagtatcc
     3661 atccatcatt gcagaaagat tgtttattct ttcagtcata tcttttccta aagcagcagg
     3721 tactatagag aaagtattag atataccatc ttgagcatgt tcatatggta atttagcaac
     3781 tgaagataat gaagctaaag caccattagt atctctacca tgcattgggt tagcaccagg
     3841 agcaaatgga gcaccagctc ttctaccatc tggtgtatta ccagttttct taccataaac
     3901 aacatttgaa gttattgtaa gtatagattg agttggataa gaatttctat aagttttatt
     3961 ctttcttatt ttattcataa agctttcaac taactctaca gctatactat caactctatc
     4021 atcattattt ccgtattttg gataatctcc ttctatttca aaatcaacag ctattccttg
     4081 ttcatttcta atagttttaa ccttagcatg ttttatagca gataatgagt ctgcacaaac
     4141 tgataatcca gccataccac aagccatagt tctaaatata tctctatcat gtaatgccat
     4201 ttctaatgct tcataagaat atttatcatg catataatgt attacattta aagtatttac
     4261 atataatgtt gctaaccaat cagtgaatgg ttcaaattta ctcataactt catcataatc
     4321 taagtactca gaagttatag gttcaaatct tggtccaact tgaacaccag atttctcatc
     4381 tacaccacca tttatagcgt ataataaagt tttagctaag ttaactctag ctccaaagaa
     4441 ctgcatttgt ttaccaattc tcattgcaga tacacaacaa gctataccat agtcatctcc
     4501 ccagtatgct ctcattaaat catcattttc atactgtact gaacttgtat ctatagatac
     4561 tttagaacag aaatctttga atccttgagg taatttagtt gaccatagaa ctgttaagtt
     4621 tggctctgga gaaggtccta atgtatatag agtatttaac attctaaatg agtttttagt
     4681 aactaatgtt ctaccatcta ttcccatacc tcctatacac tcagttaccc aagttgggtc
     4741 tccagagaat aggttattgt aatcaggagt tcttaggaac ttaaccattc ttaatttcat
     4801 aacaaaatgg tccatatact cttgtaattc ttcttctgtt acgattccag cttttaaatc
     4861 tctttcaaag tatatatcta agaaagtaga tgttctacct aaagacattg cagcaccatt
     4921 ttggtcttta acagcaccta aataaccaaa gtataaccat tgtacagctt cttttgagtt
     4981 agttgctggt tttgagatat caaatccata agattcagcc atttttttaa gttcatttaa
     5041 agctgatatt tgctcagtta tttcttctct taatctgata acttcctcat ccatgcaaga
     5101 aacttctaat gatttctttt gctcattttt atcttctatt aaagcatcaa caccgtatag
     5161 agcaactctt ctgtagtcac caattattct acctctacca taagcatctg gaagacctgt
     5221 tattatacca gattttctag cagctctcat ttctggagta taaacatcaa aaactccttg
     5281 gttgtgtgtt tttctgtatt tagtaaatat atcttttatt tctgggtcta attcatatcc
     5341 aaaagcttcg catgaatttt caaccatctt tataccacca tatggcatga cagctctttt
     5401 taaaggggca tccgtttgta acccaactat tgtttctaat tctttatcta aatatcctgg
     5461 agcatatgca gctattccag aaacagtttt tgtatcaaca tctaaagtac caccattttc
     5521 tctttctttt ttaaatagga ccattgcttc gtcccataat tttttagtat tttcagtggc
     5581 accagctaag aaagagtcat ttccctcata tggagaatag tttaattgta taaactctct
     5641 aacatttatt tctttagtcc atcttcctgt tttaaatcct tgccatgcat tcattaagta
     5701 tttcctcctt agatttaaat gataaataat actattaaaa ttaattttta tatacttaat
     5761 ttattttata tattttttta aaaatatatt ttctaatata ataatagcat attattcgta
     5821 tcctgtatac ataaaaaata aaaaattgtc gctttaaagt ataaaacaga ttatatgtta
     5881 ataatgtggt gaaattatac ccatatataa ataaaataaa acaaataaat agctaattaa
     5941 ggagaaaata ttttttattt tttgtttagg ataaataaat tttattatgg aaaaaagaaa
     6001 aagcatacat cttcacaaac tgaatattta tttaataggg ggaggtgata gattgtttat
     6061 cacagtggta ttatttttag taggtttcct attaattact aaaggcgcag atatctttat
     6121 aaattgtact gtagagatag gtaaaaaaac gaatatatca gaaattatac ttggagctac
     6181 tatagttagt tttgcaacaa cattacctga gtttacagtg tctctacttg cttctattga
     6241 tggtcatact actatgagtt taggaaatgc agttggttct ataatatgta atacagggtt
     6301 agcattaggg ttggttgttt ttataagtcc atttaatgta gataaaaaaa tgtttttttc
     6361 taagtcttta ctattaatag tatccgttat agttttaatt ttattgagtt tagatggagt
     6421 tataacaaga ggtgattcat tattacttat aataatatta atcttttata tggttaataa
     6481 ttatagaagt gtcgttggaa aatctgatac taaaaataga aatattaaaa ataacactag
     6541 taaagacata tctactaaaa aagggaaaaa ttataggggt ttttccgtat tagaaattgt
     6601 aaaaatacta ttactttttg ctacaggatt gataatgatg ataataggtt cacaaatcct
     6661 tatagagagt ggagtaataa tagctagttt tttaaatata cctcagggta tagtaagttt
     6721 aactataata gcacttggaa cttctctgcc agagatagtt tcgtcgatta ctgctataag
     6781 aaaaaatcat catgaaatat cagtaggaaa tattttgggt gcaaacatat tgaatatagt
     6841 atcagtaata gctgtatcag caataccaaa taacatacca atactatctc aaaatagaca
     6901 gttggatata ccattcatga tattattatt attaatagta ataataccaa cacttaaatc
     6961 taataaactt agtagaatac aaggtatatt gatgttattc acatattttc tgtacatatc
     7021 aattttgtat ttcatgtata ttatttaact atactgttta aaatattaat tgcagaatat
     7081 cctaaaaaag tatataatgg ataggttaag attaattgat aacggagagg aataatatat
     7141 gaatataaca aagtttgaag atttaccaat aagtgaggga ataaaaaaag ctatagctga
     7201 aatggggttt gaagaaccat ctcctataca agcacagtct atacctgcga ttttgtcagg
     7261 taaagacgtt ataggacaag ctcaaactgg tacgggaaaa acagctgctt ttagtatccc
     7321 tatactagaa acaatagacc caaataatag aagtttacaa gctgtagtgc tttgtccaac
     7381 aagagaactg gcaatacaag tatcaacaga aataagaaag ttagctaagt attcgcacgg
     7441 aataaagaca ttacctatat atggtggtca gccaatagat agacaaataa aatctctaaa
     7501 gagtggtgtg caagttgtaa taggtacacc aggacgtaca atagaccata tcaatcgtaa
     7561 aacattaaag atggataatg taaaaatgat tatattagat gaagcagatg aaatgctaga
     7621 tatgggattt agagaagata tagaaatgat tttaagtaag attccagaag aaagacaaac
     7681 aactttcttt tcagctacta tgccaagagg aattttggaa ttaactaaga gatatcaaaa
     7741 agacccagag catataaaag ttgttagaaa agaacttaca gtttcaaata caaagcaata
     7801 ctatatagaa actaggtcat caaataaatt agaagtatta tgtagattag tagatgtata
     7861 tgaccctaaa ctatctgttg ttttctgtaa tactaagaga aaagcagacg aattggtagg
     7921 agatttacaa gcaagaggat attttgcaga tgcattacat ggtgacttaa aacagactca
     7981 aagagatata gtaatggata agtttagaaa tggtacaata gatatacttg ttgctactga
     8041 tgttgcagct agaggtatag atgttgatga tgttgaatgt gtattcaact atgacttacc
     8101 acaagatgaa gagtattacg ttcatagaat tggtagaact ggtcgtgctg gtagagaagg
     8161 tatgtcattt acttttgtat ttggaaaaga aatgagaaag atgaaagata tagaaagata
     8221 tactaaatct aaactaataa agcataatat accaacaata actgatgttg aagagaaaaa
     8281 agtaggtact ttctttgcac aagttaaaca aactatagaa gaaggtcact taactaaaca
     8341 attacaatgg ttagaaggtt tctgtaatga tgaagattat gcaatggttg atatagctgc
     8401 tgcacttgta aaactatctc taggtgaaga aatgaaagaa gaaataatag aagaaaaacc
     8461 tagaagagag cgtggagata gaaaaggtgg tactggagct aaagatggta tgattagatt
     8521 atttatcaat attggtagaa atcaaagagt acaagcaaaa gatatagttg gtgccatagc
     8581 tggagaagtt ggaataccag gtaaagtagt aggtactata gatatatatg ataagtatac
     8641 ttttgttgaa atacctaaaa aagatgcaaa aacagtaatt gaaaagatga aagatattaa
     8701 gataaaaggt aataagatta atatagaaaa agcaaataag aagaaaaaat aacgtatagt
     8761 atacaaaact ataattagaa aatatataaa ataatatatt ggatatttaa aaagcctgat
     8821 gtgttttcaa aacagatagt agataatctg taagagttaa cagcataagg cttttcttgt
     8881 tttatatgat gttataattt tccagattat tgtgaaaaat gtatattagt tccttttttt
     8941 caaatctgat ttgaaaaaga gaatattaat tatctatata gtttagatta taataaaaaa
     9001 tgtaagataa caaaggggag aaaaagatgt caatgactta tatggaccct agggtttttt
     9061 tgattttaga aatggtgtta gaagaagaca caaatactct agaacaattt tcaaatgttt
     9121 tgggtgttag tactaggact atcagaaact atataaacca gattaatcga gaattaaaag
     9181 gtggtattgc taaaatagtt aaaaatgaaa aaggtacata tagtataaga attgaggatg
     9241 aaagtaaatt aattgagatt gtaaatttta atagaggaaa gctatcaaat tttataaatt
     9301 taaattcacc tgatgaaaga ataaattatg ttcttgatat tttaactatg accaacaatc
     9361 caattaccat agatgatttg gctgaagaga tatgtatagg aagaacaaca ttaataaagg
     9421 atttaaaaaa agcagacaga attttagctg aatatgattt agaattaaaa aggaagccaa
     9481 atataggtat gattttagtt ggtgaagaaa tggatataag attattaatc cttgatagat
     9541 tgtatgaaaa ttatattgat gtcttggaaa acgttaatca gataaattta gttaaagatt
     9601 atgatattga atgtcttaga gatgaattaa aaaagttatt taaaaaagaa gaactctaca
     9661 taacagaaca ggtcttgaga gatgttgaaa gatatataat catgtctgtc ttaagaaatc
     9721 taaatgggta caaatttgaa aagatagata agagatttga agtgataaga tgttcagatg
     9781 aatatacttt aggattaaag ctcaaagatt tattggaaaa gatatttaat atagttttaa
     9841 atgaaaaaga aaccatattt ttgacaatgc cattaatagg tagaaaagct cctagtacaa
     9901 aattagcact tagcagtata aagataaatg atagcgtaaa ggaagttgta gatgaagtaa
     9961 ctagtttttt attagagacc tcagggattg attttaaaga agataaaaag cttatagaaa
    10021 atttggaata tcacttgtat tttgcactta atagaatgag attcaacata agggtaaaaa
    10081 atcctctttt acaagaaata aaggaaagat atacatttcc atatagtgtt gcaaagatag
    10141 ctgcaatgat aattgaggaa aagtttgact tgaaaatatg tgaccacgaa ataggatata
    10201 tagcattaca ttttggaagt tattttgaaa aaaattcaag aaaagttcta aatgtaaata
    10261 gggtagctgt tgtttgtgga acaggtcttg ggactgcaca acttattaga ataaagatag
    10321 gaaaaatact tggagaaagt gtagaagtaa atactttttc tgatatagaa gctaaagcta
    10381 atttagattt attaaagtat tatgatttag tatttacaac agtagatttc aaaacagact
    10441 tagatgttcc aatttttaga gtaaatgcgt tatttaatga agaaagtata aagaaagaga
    10501 tagaaaatgc aatacttttg aaaaatagta taaatcttaa gtctataaaa aagattgaaa
    10561 aaaatatccc ttttataggt aaattaattg aagaggataa gttctttata ttgaataaga
    10621 gtacgtttat ggaaaattta gaagatatgt tagaaaaatt agttcataaa ggaattattg
    10681 atatagagtt caaaaaaaag gtattaaaaa gagaaaagaa atcttcaaca gcattagata
    10741 attatatagc attgcctcac tcagttaata ctaatgggga aaatctttat ctggcatttg
    10801 gaatattaga aaaaccagtg atttgggata caaaggaaat tagaataata atattgatga
    10861 taattccaga taagaatgta gatagtacag acctgataat aaaaagttat gaagaagtac
    10921 ttgaagtagg gagagataaa aagatggtag aagaacttgc taaggcaaaa tcatttgatg
    10981 aattttataa aataattacc aagaggaggt aataatatgg acccagtaat ttttattata
    11041 gcatcactta ttacagtgta tttattaaat atttttcttg gatacttaca gcttaaagat
    11101 tttaataaaa attatattga actaaaaaga aaaggaagag tggcaattgg cagaaaaaaa
    11161 ggaagaattt catcgggtac aattgtgttg atacttataa atgatgatgg tgtgattgta
    11221 gagactagaa aaatgcaagg tgttacagta ttggcaagag taaagtcatt tgaaggtttg
    11281 gtaggaaaga gcttagagta tatagaaaaa tcagatttaa ctgtttacaa taaactactt
    11341 aaaaaagcaa tactagatgc agtcaaacag tacataacat ttgagaaaaa taaatgtgaa
    11401 gatacaaata atctgagtac tgatgaagag tgtaggatgg aagtagttta aaaaaatata
    11461 tttataagga ggagttaata tgacgcaatt ttttcaagta ttagcaagtg gtgcagatag
    11521 ttttatgaat ttatttaggg caggtgggca acaatttgta ggttttgtaa cagatatagt
    11581 accactttta gtagcattat tagttacaat gaatgcaatt atcaacttta ttggtacaga
    11641 tagagtcgag agacttgcaa aaaaatgttc tgcaaatata tttactagat atttgatatt
    11701 accagtcctt ggtacatttg tatttgcaaa cccaatgaca ctatcattag gaagattctt
    11761 gccagaaaag tttaaaccta gttactttgc agcagcaagc ttttcatgcc atacaatgaa
    11821 tggattattc ccacatatca atccaggtga actatttata tatctaggaa ttgcaaatgg
    11881 tataacaact ttgggattct caacagcaga tttagcagtt agatatttgt tagtgggtat
    11941 agttgcaaac tttattaaag gtgtagttac tgactataca acaaaatttg tagagaaaca
    12001 acaaggaata gcattaaatt cagatataaa gattggataa ttactttaag gtataaataa
    12061 atttttcaaa taaaaagata gtgtatagag gaggataaat tatatggcat ttaacaaagt
    12121 taaaatagta aaaggttctg gaggatgggg tggaccattg ataatagaac caacagaaaa
    12181 gaagaataag gtagtatatg tgactggggg agcaaagcca gaaactgcag taaaaatagc
    12241 tgaacttaca ggatgtgagt taatagatgg attttcacag ggtgttaaag atgatgaaat
    12301 cgcatgtgta ataataaatt gtggtggaac attgagatgt ggtatatatc ctcaaaagaa
    12361 aataccgact ataaatataa tgaaaacagg aaaaagtgga ccattagcaa tgtttataaa
    12421 agaagatata tatgtttcag gggtaaaacc aacaaatgta gagcagttat aattgaggta
    12481 gtaggaggga agaaatatgg cttatgatac taaaaagaag ataagtgagc agagtcaagg
    12541 aattgttgca aaaataggta tagcactagg aaatttgaca agtactcttt ttcaagctgg
    12601 tagggatact atagatacat taatacatac tatactgcct tttatggctt tcgttgcagt
    12661 cctaataggt ataataaatc aatcgggtat aggaaattgg gtagccaatt tacttactcc
    12721 attaatcgga aatgttggag gtttagttgt cttatcaata atatgttcat ttccgttgtt
    12781 gtctccgttt cttggaccag gagctgttat agctcagata gtgggggtat tggttggtac
    12841 agaaatagga aaaggaaata ttccaccaag tttagcatta ccagcattgt ttgcaataaa
    12901 ctcacaagca gcttgtgact ttataccagt aggtcttggt cttgcagaag ctgaacctga
    12961 tacagttcaa gtaggagttc cgtcagtttt atattctaga tttttaacag gtgcaccaac
    13021 tgttctatta gcatggttag caagctttgg gttatataaa tagaagaata ctttataaat
    13081 aattagagag aggttcagtt gatatggaat taatatacag tactcaaata aataaaatag
    13141 gagataatgc aaatgaattt ttacaacata atatgtttgt aactttcaaa gataatgctc
    13201 ctcaagagtt agaaaattac tgttatatac attctgaaaa taatttagta aaagaaatac
    13261 ttacggatga tgtgctatca ataaataatg ttgattacaa aattacttct gttggtgagt
    13321 tagtaaacca aaatctttca gaattaggtc atataacatt taagtttaca ggtgaaaaag
    13381 atggagcaat tggaggaacc ttatatcttg aagaaaaaga aatagcacct attggcgtag
    13441 gtactatact aaaaataatt agaaaataaa atttaaaacg aatctaatca tattataagt
    13501 aaattataga taaaagtcaa tttaactaat caagttaact tttaatgtga taaaaaaggg
    13561 gaaatgaaaa tgagaaaagt ggctttagtc gttggaggag gaagaagttt aggtgaatat
    13621 ttatctaaac atttagctaa agtaggttat gatgttgcta ttgcagattt aaatgaagac
    13681 aacgcaaaaa aagtagctga agaaataaaa actgaatttg gttgtaaatc tgtaggatat
    13741 agttgtaatg ccatagatga aagacaggtt ataagtactg tcaaagctat tgaaaatgat
    13801 tttgatagaa tagatttatt agtgtacaat gcaggagtgg ctgtaagtaa aaaaataact
    13861 gattttggat acaaagattt taaatttatt gtagacgtaa atttaaatgg gtactttcta
    13921 tttgcaagag aagtatctaa agtcatgata gcaaaaggta ttgagggtag aataatacag
    13981 ataaattcaa aatcaggtag agtgggaagc aagcataatt caggatattc agcaggtaaa
    14041 tttgctggag taggacttac tcaaagttta gcgctagatt tggcagaaca taagataact
    14101 gtaaatgcac tgatgctcgg taatttactt gattctgata tgtttgaaag tttaattcct
    14161 caatatgcag taaaattggg aatacctgaa tcagaagtca agcaagttta tatagataaa
    14221 gtacctttaa aaagagggtg tagatttata gatgttgcaa atatgcttac attttatgct
    14281 tcaaaggaag ctgaatactg cactggtcaa tctataaata ttactggtgg acaagttatg
    14341 taaggttttt atggagtgtc tcaagatgaa ctctttagtt catgaggcac ttttttgtat
    14401 aaaattaaat atattttcag catttaaaca atgaaaaaga ggtttatctt tattttgaga
    14461 tagcctcatt tttgtaatta aaaaacatag tgtttaagta aacatataag attgttagtt
    14521 ttttaaaaga gaatttttta ataatattat atttatgaag tatttttaaa cttaatttga
    14581 taaaatatag ctatgtttta tatactgtag ttttgaacat agaaagttta ataaattata
    14641 gtatatatgt taatttttaa taaggtaaga aagtagaaag aaggatattt tatggatata
    14701 ataaaaaaat taagtcatgg gtgtacatta gattgtcatg actgttgtaa attcaatgtt
    14761 tatactaaag gaaataatgt agtaaaaatt gaaggagata aaaatcatcc ttatacaaaa
    14821 ggttttatat gcaaaaaagg gatggcccat ttagatagat taaatcataa agatagaata
    14881 aagactccta tgcttaaagt tgatggagta tggaaagaga tttcttttga taaagctata
    14941 gaaataatgg cagaaaagct tacatactat aaagaaaagt atacatcaaa gtctgtcatg
    15001 cattatgacc aatatggaag tgggtctgtg ctaaaataca taggagatat attttttaat
    15061 ttttatggag gtgttagcag acataagggg ggtccctgtt ggagtgcagg gatgcatgct
    15121 caaaaatatg attttggagt agctaagagt catgctatag aagatatgtt aaatagtaaa
    15181 agtatatttg tttggggaaa aaatccagca tatactacaa ttcatactat gcaaataatt
    15241 aaaaaagcta aagaaaaagg gataaagata gtagtgattg accccatata tacaaaaaca
    15301 gctcaaatag cagataagta tgtacaagta aatcctggaa cagatggagc tttagctata
    15361 gctatggcaa aaattatagt agaagataaa ttatatgatg aagaatatat aaactcgtat
    15421 gttattggtt ttgaagaata taaaaaatat ttatcttcat tggaattaag ttttttaatt
    15481 gatgaatgtg gtgttaaaga gaatgatata agagagttag tggatttata tactaacaaa
    15541 tattcaagta taaatgttgg atatgggctt caaaaatata aaaatggtgg aaacacaata
    15601 agagcaatag atgctttagg tgctataact ggtcaaatag gatttagtgg tggaggggta
    15661 aactatgcta ataaagttta tccgagtgtt ataaattctg acccttacaa tagccaatca
    15721 tatggtgaag atagggagtt ttatgtaagt aatatcagta aatttataga agaatcttta
    15781 aaaaatacat caaataaagt aaattatgca tcagatgaac ttgatatgac atcaaataaa
    15841 gtaaattatg tatcagatga acttgatata acatcaaata aaacagatta tatatcaaat
    15901 gaattgtata atttatctaa taagtcaatc aaagataata ttcctataaa gatggctgtg
    15961 ataactaaaa gtaatatgct gaatcaactg ccagatttag tagaattgga gagggtgttt
    16021 tcaaaaattg aatttaaagt atgttttgat atgtttataa ctgatacagc tactttatgt
    16081 gacatgttta taccatgtac aaatacacta gagagtgaag atataattta tagttcaatg
    16141 accaatccat atataaccta taatgaaaga gctgtaaagc cagcacataa attgatggat
    16201 gaatattact tctttatgga gctagctaaa aagatgggat taaatgatta tccttttgta
    16261 gaaaagagaa cttatttaga aaaagtgatt gaaccactta agcgttttga caaaaatctg
    16321 gatatagaaa aacttaaaaa caattacttt actatacata accctgttgc ttgggaagat
    16381 aagaagtttg agactccatc tggaaaatac gagctttatt cagaaagtat aaaaaacttg
    16441 ggaataagtc caacacctgt atatataagc aataaatata aagaaataga agataaaaat
    16501 atttctttta gattattaac taatcatcat gcagatactt tatttagtca gcattttatg
    16561 gacaaaaaat ctatagctca agcatatata aatcggagaa tggctaaaaa agtaggtatt
    16621 gaggacaaag atattgtgat attgaggtca aaaaaagcaa aaataaatgt acaaataaat
    16681 atagatgatg gagtaggtaa ttatatagta aaaatgtatg ttggttggtg gaagaaacat
    16741 ggaaatccta atagtttaac agacactggt atatcagatt ttgggggtca ggtaacatat
    16801 aatgaaagta tggtagaaat aatacgacaa aactagttaa atttcattga aggaataaaa
    16861 atataattat agaattgatt aaaagttact atttttacaa aactattgaa ggagggattt
    16921 ttgatggtaa attattcctt agaacataag aatctataca tagaatttat gtgctcagaa
    16981 ctagaccacc atgtagccaa tgaaataagg gaagaaatag ataacttatt aagtgtaaat
    17041 caagtaaaaa atgttgtatt taattttgaa aatattaatt ttatggattc ttcaggtata
    17101 ggcgtcatca taggtagata taaaaagatt tctaatgaag ggggacgagt ttcagtaatt
    17161 aatataagtt cacgagttaa gaagattttt gatttatctg ggttaaataa aattattggc
    17221 atttatgata cgtatgaaga agctctaagt tctttgtagg gaggagtatg tgatgaataa
    17281 tattatggaa gttaaatttt cggcaatatc tgaaaatgaa agtttagcaa gagttatagt
    17341 agcatccttt gcagctaagt tagacccaac agtagatgag ttagtagata taaaaactgc
    17401 tgtctctgag gctgttacga atgctataat acatggatat gaagaagaca gttctaagtt
    17461 tgttttctta agatgtgaga tagaaggaaa tactataaag attatagttg aagatgaagg
    17521 gtatggaata gaaaatgtgg agaaggcaat ggaaccactt tatacatcaa aaccagaact
    17581 tgatagatca ggaatgggat tcacagtaat gaaaagcttt atggacgatg tagaggtaag
    17641 ttctgtaaaa gataatggga ctagaattga aatgactaaa aaaataaatg tgcctaaata
    17701 aagtccaaaa gtgaggtttt attatggaag taactgttgc cagagaagaa aaaaaacctc
    17761 ttcttagtca tgaagagact ctagaactta ttgaaaaagt tcaaaatgga gatgaagagg
    17821 caaaagaaat attaatatca agcaatttag gtctagttag gagcgttgta tctagatttt
    17881 taaatatagg atatgataga gaagatttat ttcagttagg ttctataggc ttaataaaat
    17941 caatatataa atttgaccca aaatttaatg taaaattctc tacttatgca gtaccaatga
    18001 ttttaggtga aataaagaga tacttaagag atgatggtat gataaaagta tcaaggtcgt
    18061 taaagcaaat agctgtaaag gcaaagatgg aaagtgaagc tttaactaaa aaattaggta
    18121 gagagccgag tatagaagaa ttagctaaag caatagatgt agaaaaagaa gatttagtaa
    18181 tggctatgga agctaatttc aatgttgagt atttgcaagg agttattcat gaagaggaag
    18241 gttctccaat atgccttatt gataaaataa gcatgaaagg agaaagtgaa gaagaaaaag
    18301 tagtggataa catattgtta aaagacatac ttggaagact ggataagaga gagcgtcaaa
    18361 taatagttct cagatacttt gaagacatga ctcaaagtga aataggagag atgctcaata
    18421 tatcacaagt tcaagtatct aggatagaga agaaagtatt gtctaagtta aaagaatata
    18481 tatcgtgata atacttatga tatgtagaat aacaaaatat aataaatata ttactaaaat
    18541 aaaatgtaat aactttttat gttaagtttt taaattatta aaagatatta aaataataaa
    18601 aagcattaaa aaagtaaaaa tataaaaaca aggtgtcttt atggaaaaat agattttttc
    18661 tttattagac atctttttta ttttttgacc aaactttaga tagtcaaaat aaataatagg
    18721 tttatttttt taaaattaac aaataatact ttagagaggt gtttagtatg gataaaaatt
    18781 ataaaaaata tgtagaccaa ataagcccaa aacctacata tttaaaaaac tatacacttg
    18841 catttattgt aggtggaatt atttgtatga tagggcaagc aataaatgat ttgtatatga
    18901 aagttggagg tcttgataaa ctaggtgcta gttctgcaac atcaataaca ttaatattta
    18961 taggggcatt tttaactgga ttaggagtct acgacctaat aggaaaaaga gctggagctg
    19021 gttctataat tccaataaca ggttttgcta actcaatagt atctccagca atggagtata
    19081 aaagagaagg ctatgtatta ggtgtaggtg caaacttatt taaaattgca ggaccagttt
    19141 tagtttatgg gataggttct tctattttat gtggaattat ttattatatt tttaagatgt
    19201 tttagatgat ttttatttaa tttaaatttt attaattatg aagaaggtat aaaatctgaa
    19261 aatagctact aaagtaacta attgaaaaat aattgtgcag atttaattaa aatttttaat
    19321 taatattaaa aatttgaata gtaaaatgca aaattaaaaa ggtgtgaaaa tatgaaaaat
    19381 aaaagaattg gaaaaagaac agtcaagtta gaaaataaac caaccataat atcaactgga
    19441 actatagtag gtcctaagga aggtgaagga ccactaaagg actattttga tatgattatg
    19501 actgacgatt tatatggtga aaagacttgg gaattagctg aaagtaaaat ggtagagact
    19561 gcatctcaac aagctatcca aaaggcaggt aaaaaattgt cagatgtaaa ttatatgcta
    19621 ggtggcgatt taataaatca aatagttcca gcatcatttg cagcaagaga actggctatt
    19681 ccatttttag gtatatatgg agcttgttct acaatggcag aaggtctttg tataggttct
    19741 atgcttatag atggtggttt tgctgattta gtactgtcag gtacatcaag tcactattgt
    19801 acagcagaaa gacaatttag attcccactt gaacttggaa atcaaaaacc aatgacagcc
    19861 cagtggacag ttacaggagc aggaagtgta ttattagctc ctaatggaga cggtccaaaa
    19921 gtaaagtatg ttactgttgg taaagtaata gatgagggta ttgatgatgg taataatatg
    19981 ggaccagcta tggctccagc agcaatagat actatctact cttactttga agatactaat
    20041 gatgacccaa atagctttga tataattgct actggagatt taggtactct tggaaaacag
    20101 atagcagaag actttctaaa agaaaaaggt gtagatatat caaaagttta tactgactgt
    20161 ggtatagaga tgtttaacct taaagaacaa gatgtccact gtggtggaag tggatgtggg
    20221 tgttcagcta cagtgtttgc aggatatata tatgataagt tgagaaaaaa agaatttaac
    20281 aaagtaatgc ttgtatcaac aggagcacta ctttcaccga caagtacact acaaaagcag
    20341 acaataccat gtgttgcaca tgcagtagta atagtaaatg agtaggaagt gatataatat
    20401 gttaatggac tatgtaagag tatttattgt aggtggaatt atatgtttaa tagcccaagt
    20461 aatgatggat tatttcaaaa tgcaaactcc atatgttatg gtaacgtatg taacaactgg
    20521 tgtagtttta acttttctag gactttatga gccattagtt aagtttgcag cagcaggtgc
    20581 aacagttcct ataataggat ttggatattc acttgctaca ggagtaataa aatcaattca
    20641 aagtgatggt tttttaggta tttttttagg aggtacaact gctacagctg gtggaatagc
    20701 agcagctata ttctttggat atattatgtc agtagtattt actccaaaag caaaaccata
    20761 aatctttatt aaaagaataa taagtttttg aaataataac tttttataaa gcaggtggat
    20821 atcttttaga ttccacctgt tttttatata aagaagcgtt tacataattg aagttgacaa
    20881 ttatttacaa catagtgtag tattatatta tcaaaataaa atgaagtgaa gtaggggata
    20941 aagatggtaa ctattaaaga tattgcaagg aatctaggta tcagttattc aactgtttct
    21001 aggtgcttaa acaataatcc taatgtatct gaaaaaacaa aaaagaaagt ggtagaagag
    21061 gcaaatagac tagggttcca ttttaatgta aatgcaagaa atttagcaaa aaaagaaact
    21121 aacaggatag gggtaatctt ttcaaataat tttaatcatc aagatactag aaagtttttt
    21181 agtgatataa tggatagttc tataaattct attgagacta ataaatacga ttttataata
    21241 cagcctaata ataacattag tggtgatagt aatgtatata aaatggtaaa tggacaaatg
    21301 gttgacggat tagtaattgt gtctcaatca ataaaaaaag aagagtatga ttttttaaaa
    21361 gacaataatt ttccacatgt atttatatat tttaaaccat cttttatagg agaagtagat
    21421 aatttctttt gggacgataa cgtgtatgga ggttatatag ctaccaagca tttaattgac
    21481 catggtcata aagatataat aacagtaact tcagatgata agagttcaaa aatgcatgaa
    21541 gatagaacca agggatattt gaatgctatg gaagaagcaa atttaaagac agaagtcatt
    21601 aaatctaaaa tggattttga atctcaagtt gaatttttag aaaaatacat tgataaaata
    21661 aaaaaagctt cagctatatt tgtacaacaa gatgtaccag cgatttctat aatacaagag
    21721 ttaaaaacta cttatggtat aaatgtacca gaagatattt ccataatagg gtataataat
    21781 attgaattaa tatcatattt taggtcgcat ttatcaacaa tagatgaccc aagagagcaa
    21841 gttataaaaa atggagtaga tagtttagta aatataataa ataaaaagag tacagaacac
    21901 attccaagaa aattatatcc aaggttaata atacgaaata gcgttaaaag aataaagtag
    21961 taagctttta agtatcaaac gtttattaaa aatattatag attatgtgaa gttttttaac
    22021 aaataatata aataaaaatt aaaaggagta ggtgtatata agtacattgt actcctttat
    22081 ttattgagat agtttttata atatgaatga ataattttat tcaattattt gaaaatccgt
    22141 tattttaaca atataaatta ataaattatt tgtattttat atcatgaatc tataatattt
    22201 ttttgattca taactaaaag tatataaaaa tgatgaataa atatatatta tacattatca
    22261 atgataggtt atataataaa atcactaaca attatattat aagaaaatta taaaaattac
    22321 aaggaggtat agaaatgaaa gaaaaagcag ggattagaaa tgccataata gcagccttta
    22381 taatcacaat attggcagaa ttaattggac ctatttcatt taaagttatg ggaattaatg
    22441 taactttact tagtatacta tgggctatat tcataggaat ggctgtttct cctcatttat
    22501 tagggagagt tataccagcc ttaaaaaagt ttatagggga taatgaaata aatgtatctc
    22561 catatttatt atctttgaca ctatatccat tagggataat gtttggaatt aatgcagggc
    22621 ctaaagttgg tatattactt caagcaggac cagcactttt attacaagaa tttggtcata
    22681 tgggtacaat gttgatagca ttacctgttg gagtagcatt aggtcttgga agaagtgcat
    22741 taggtggtac tttttcatta tgtcgtgaca cagcactagg aattattgga gataagtatg
    22801 gattaaactc accagaaggt ataggaacac taggaactta cataagtggt agtatatttg
    22861 gaacattatt attttcattt ttagcaccag tgggtgtact tttaggattt catccatatg
    22921 ctttagcaat ggcatcagga atgggtagtg gttcaatgat gggagctgca acagcatcat
    22981 taatgaatac agttccacaa atgtcagagc agattttagc atattcagct actagtggat
    23041 tgattacagc tgttactgga atatatatag aattattctt atctttacca gtagccaact
    23101 actattatag caaagtagct ccagttattg aaagatttag aggaagaaaa acaagaagaa
    23161 caagtaataa attgtaaagg aggatatata tatggaaaaa acttttaaga ctattatgga
    23221 gcagataaaa atagtattgt ttatatatat tattatttgc tttggacaaa tgatagcact
    23281 taagactcag gctcaagatt tgttgattgg aagtgtatct ggatttttgt tggtgataat
    23341 tgctattata ataaagaatt ttgttaaaaa acctaattta ccaggttttg catgggctac
    23401 attagttgca tttgttttat cgcttccaat atctccagtg ggggatatca tagcaacaaa
    23461 tgtagggaaa atcaatttta tgtctacagt aacaccatta ttagcttttg caggaatctc
    23521 tgtaggtaac caattagata tattaaagac tttgagttgg aagttagtag ttatatcatt
    23581 tatagttatg acatctactt actttggttc tgcttttata tctcaaacag ttttaagatt
    23641 aaatggaatg ctttaaggag gtagtaaata tgaatgaatt aaaagcaaaa attaaagagg
    23701 aaataaagtt attatctgaa gagaaaaaga catcatttga aaaagtttct gactatttat
    23761 tttcaaatcc agaattagca tttgaggagt ataagtcaca aaaagcatta tgtgatttgt
    23821 tagaagaaaa tgaatttaat gtaactaaag gtgtaggagg attagaaaca tcttttgaag
    23881 ctgtgtattc aaatggaact aatgggaaaa cagttgcttt tttagctgaa tatgatgcac
    23941 ttccaggaat gggacatgca tgtgggcaca atatcatagg gacaagttct gttggtgcag
    24001 gtatcatatt aaaagaaatc atgaaaaaac ataatataga agggactgta aaggtttttg
    24061 gaacacctgc agaagaaaga gtaggtggaa aaataactat gattaaagaa ggtgtattta
    24121 ataatgtaga tgctgcatta attttacatc caagtgatgc ttcaatgcct gatgatatat
    24181 catttgctca agttaattta aaatttgatt ttactggtaa ggcatcacat gctgctgctt
    24241 ttccttggga agggaaaagt gccttaagtg gagtaatagc actatttaac agtgtaaata
    24301 gcatgagatt acatcttaaa gattatgcaa gagtacatgg aattataact gatggaggta
    24361 gcatacataa tataattcct gaaaaatcta cagctatatt taatgtaaga gctttaagca
    24421 tagaatattt aaatgagatt tgtgaaatgc ttaaaaattg tgctaaagga gctgcaattt
    24481 ctactggaac taatgtagaa atagttcaat tagatgaaat atacaaagag attaagaatg
    24541 attctgaatt agtgaatata gttagacaaa attttgaagt tttgggtgaa gactatgttg
    24601 aaagagattt aagtcaaggt ataggttcaa ctgatacagg aaatttaact catgagatac
    24661 ctgcaataca agcatatata aaattaaaag aaaatactgc aactcataca gatgaatttg
    24721 ctgttgcagc tggtggtgaa gaaggcaaag tagcacttat aaaagcaatt aaggtgctag
    24781 caatgtgtgg agtagatatt ttgtatagta aataatatat aattttaaaa tatattaaga
    24841 aaggaaatca gattagacat gatattaaaa caagtaatag aggtttatga cattttagat
    24901 aaagcaaatg ctaatgggga agaagtaaaa acttacttac aaggttatgg tgaagtagat
    24961 gtaactgtaa aagaattgtc ttcaagtaaa ggctcaacag atttagtaaa gcttacaatt
    25021 cctgggaaaa atggaaaatt aaaaggtgga gatgctccta ctcttggcat tttaggtaga
    25081 ctaggaggga ttggagcaag accagaagtt ataggttttg tttcagatgg tgatggagca
    25141 ttggtagcaa ttgcagtggc tgctaaactt ttggatatgc aacgaaaagg agatatatta
    25201 gatggtgatg ttgtaatttc aactcatatt tgcccagatg ctccaactaa agaacactat
    25261 cctactcctt ttatggattc tccaattgat atgatgacta tgaatgaaaa tgaagttgat
    25321 agtagttgtg atgcaatact ttctatagat actactaaag gaaatagagt aatcaatact
    25381 agaggatttg caatatcgcc aactgttaaa gaaggctaca tattaaaaac tagtgataac
    25441 cttttagata ttatgcagac tgtaacaggg aaatctccat ttgtattccc tttgtctatt
    25501 caagatataa caccatatgg aaataatctg tatcacttaa atagtatttt acaaccagca
    25561 gtagctacag atgcaccaat agtaggagta gcaattacaa cagagatgcc tgttgctgga
    25621 tgtgctacag gtgcaactaa ttttagtgat ttagattcag ctgggagatt tgcaattgaa
    25681 gttgccaagc tatttggtag aaataagtgt gatttctatg ataaagaaga gtgggaaatg
    25741 cttattaaga gatatggcaa attaaataga tttcaaacat ttggtataca gtaattagaa
    25801 aaatattaag tttatataat ttgtgatata actatttaag aatatataaa caattaggaa
    25861 taaaagtaag aataaagcac ttagttaaaa actttaaaaa taaaatattt atttgtttat
    25921 ataaaaaagg aggattctgg ttattgggat tctctttttt atgaatacaa ataatatatt
    25981 gtaattataa aaaaaggagc gtttcaaagt gattttttta atcaccttga gacaactcct
    26041 tatattttta tttaaattct attttttatt aagttgctgg agttccacca ccatcaggag
    26101 gagtagtaga gccaccacca ttatttccac caccatcagg aggagtagta gagccaccac
    26161 cattgtttcc gccattatca ggaggtgtag aaccgccacc accattattt ccgccattat
    26221 caggaggagt agtagagcca ccaccattgt ttccgccatt atcaggaggt gtagaaccgc
    26281 caccattatc acctgtgtta ttattgttat tattattttc ttctggttgg ttattgtctg
    26341 gtttttttgt atcttcagat gatggttgag aacttacttt agtaggagca gtaccttcaa
    26401 taaatgctgc tttagagcca gaagattgct ttcctccatc ctctaaatta atttttgtaa
    26461 aatatacatt tttaggaact tcaaattcag taaccgttaa attagcatgt attttttcca
    26521 taattttttc ccataatttt gcagtgctag tacttccatg tggtacttct ctacgtttta
    26581 tagtgttacc agaatcatct tttctaccag catcatctcc aatataagtt gcaccaacat
    26641 aataaggagt gtaaccgaca aaccaagcat catatgcaat atttgtagta cctgttttac
    26701 ctgctacagg cattcccttt ggaagtgcag caacaccacc agtaccttca gtaattacac
    26761 tttctaacat atctgtaacg acataagcta cttcaggttc tacaacttta tgttcctcag
    26821 gagcattttt aactaataat tgaccatcaa aggtagttat agtagtaaaa atagaaggtt
    26881 ctacataaat accgtgattt gccaatgtac cataagcagc agccatttga agtggagtaa
    26941 taccattcgc cataccacct agtgtcaatg atgggaatat tctatcactt gcttcagatg
    27001 aacctgagtg attattcttt aaagttgtta taccaaagtt ctttaagtaa tccatcatta
    27061 tatctacaca ttcatcataa gagtctccaa gcattccagc agttttgaca gctatcgtgt
    27121 ttgaagattt agcaagtgct ttacgtaaac tcatagaacc atgaccagca gtagtagttc
    27181 ttggattcca tttattattt tcttcaaact tatatcctcc tcgagaatca cttagagcag
    27241 ttgcttgtgt tatttttaga gtatcaatag ctggcgtata tattgctaaa ggttttatag
    27301 aagaacctgg ctgatgaggg ttagtagcac gatttaaagt ttttctacca cttatatttc
    27361 ttcctccagc tagtgctctt atttcaccat ttttataatc taagattacc attgcagctt
    27421 gcggttggct aactccatca ggaccaacca tatgtcctgg gaaattgcta tttctatcaa
    27481 attcttcttc taaagcatct tgcattttag ggtctatagt tgtgtttaca attagaccac
    27541 cattgtagaa taagttttga gcttcatcat ttgtatgtcc ttgttccatt aaagcattta
    27601 taacttcact ttcgataagg tcttctacag atgaagaaac tttatctgat gattgaggca
    27661 attttatttc tattttagct ttgattgctt catcatattc actttgtttt atatatttca
    27721 attctaacat tttctttaaa acaatttctt gtcttttttt agcttcagga ttacttacag
    27781 cctttctaac aactaatgta cctgctttta attgtctata agtatcatta gatataagct
    27841 cccaagattt tattttttca atcatatcaa agtccacttg agtagggtca tctaaatcat
    27901 catcagttgt gttaacaaaa aataataatt tattctctaa atcctcctta gtttcatttc
    27961 cctctaactt agaagtttta taggctgaaa atcttgatgg atttttagtt gaaccagcaa
    28021 gaagtgctga ctctgctaga gtaaggtcag ctgcagactt atcaaaataa ccacgtgcac
    28081 cagcctcagc acctgctaga cctctaccaa cgaagaagtt atttaaataa gtttctagta
    28141 ttttatcttt acttactgtt ttactcatct catgtgcata gtaaatatcc tttattttac
    28201 gaggtatagt ttgctgttca gttgttaaca gcattttgga tacctgcata ggaatagtac
    28261 taccaccttg cttagtacct gtaagggtct ttaatactga cctaaataaa cctttaatat
    28321 cgacaccctt atgctcataa aaacgctcat cttctattgc aattacagca tgttgaagat
    28381 aaggggaaat cttatctaat ggaacgggtg tctttttatt tacacttgga gctgtagata
    28441 atgtttttcc attagcgtat ttaatagtag ttgtttggtt cgtctgttta tctaaaacag
    28501 cttctgtaac tggagttaca tctcttagtg acgcaaatac tagaccagca gtacctgctg
    28561 taccaacaac tagtaaaact aaaaatacta tcccaaatac tcttagtttt ttaaatttat
    28621 cgcttttttt agattttttc ttgttttttg ttgaacgagt cttgttagct gaagttctat
    28681 taattggttt atttgtatta ccagatgagc taactttttt tctcctgatt ttatttccat
    28741 ttttatcatt atcgttattc ataagatttt aacctcctta cttaatgcaa tattataaca
    28801 caaataggag tagttttgca attaatagaa aaaatgaatt tgctataata ttctgtacat
    28861 tgtatatgta taaacgtaat atattaaaaa gtctatattt ttattttatt tatttttgac
    28921 aaatattata aaaattatgc caaagctaca tataaataaa taggagggga taattttgaa
    28981 tagaatagta gatagaaaaa caaaaaatga atttagaaaa atcatagcta tttttttagt
    29041 aattcttttc ttgtctgtat ttataggcag ttttatatat atagataaaa ctttaagacc
    29101 aacaataaca gttttagcag agactaaagc tcttgaacta gcaaataggt cgataaataa
    29161 agctgttgct gaaatggtag aaggaaaaat aaattatgaa gatttaatgg atatacaact
    29221 tgataataat ggtaaaataa ctatgataca agcaaacact ataatgatga atgaaattgc
    29281 atctgcaata gctttagaaa tacaagatga attaaaaaag gataagacag caagttctta
    29341 catacctata ggaacagcat taggaagtcc tatattagct aaatacggtc ctaaacttga
    29401 agtatctatt gaacctatag gaacagtatc agtaaacttt aaaacggaat ttgagtcttc
    29461 aggtataaat caaactagac atagaatata tttagaagct caaacacaag ttaaagtagt
    29521 aataccactt ataacttcaa caaaacaaat taaagctcaa atacctattt gtgaaactat
    29581 aatagtaggt gatgttccag aaagttatgt aaatattcca gaaaaaaatc taggaaatgt
    29641 tttacctaac actggaaaga ataccaacaa gtaatataaa gttgtatatt tttaaataaa
    29701 ttcaaaataa tagtttataa ataaaatttt tggaaataat attaatataa ttttaataaa
    29761 aatttatatt ttatactatg taaaatatct aatatatttg gtctgtaggt taaataaaag
    29821 tacctttaga ccaaatatat tattaataac ttaataacat cttaaaactt atttatttat
    29881 attatttaca acatccattt aataaataca ccataaccta cagctgggtc gttttcaatt
    29941 gcatgtgaca ctgctccgat tattttatta tcttgaacta ttggagtacc actcatacct
    30001 tgtacaatac caccagtttg agctaaaagc tttttatctg taattttaat tttaaaactt
    30061 ttactttctg gatgtttttg gttttctata tctataattt caatattata ttttttacac
    30121 ttattaaagt tatcttgtaa aattatttga gcttttccta atttaacttc atctaaagat
    30181 gctactttat atttttttaa cttggaaata tcaaagttat taatttgacc tcttattcca
    30241 aaatcagtat tttctgtaaa gctaccaata atattttctc gttttgcatt tatacatcca
    30301 acactacctt tataagattt ttctatatta aggtgcttag ttgtagaaat tgaacctgtt
    30361 ttaataggta tttttcttgc attaccaaca cttattggat gacctacagc tccaaactct
    30421 gatgtatctg gattgatata cgttaaagta gcaaatccag aaagtaaatt gttaaaacta
    30481 attttttcta atatgtgttt ggtagttttc attgttataa gttgtccacc tctatttaat
    30541 aaaatagata cttgtttttc ttctggtaaa gcatttaagg tattggcaaa gtcactatat
    30601 ccatcaactt cagcattatt tacctttact atagcatcac ctaatctaaa tggagatgct
    30661 tctccaggat ttctaactat gatatttttt aattctgcgt caatttgaag tacgtttcca
    30721 attggtatta aatattcagg ttcatttttt tgtaaatttt gtgcataaat taaattattt
    30781 gagaaaaaat ataataaaaa taaaaatgtt aaaacaattg taaattttga cttagctaag
    30841 ttggtttttt tacttaaagt attattttta aaatgaaaat ttttaagttg cataaaacac
    30901 ctctttctta ttaaattatt ttaataatag aattgaagtt ttcttgctgc ttctatatta
    30961 tgttgtgcaa gaatcatgtt ttgatgcttg gaaaactagc tcaataacac cttagttttc
    31021 ataaaaataa ataaaataaa tagtgtatat gataaaataa atacatattc atataaataa
    31081 aaataaacaa taactgtcta gcataagaaa ggagcaaaaa atgaaaaaat atagattgtt
    31141 agttacttgt ataattgcca tgggaatcat aattatagga acatcaaatc cagttagcaa
    31201 tttttacaag actacaaatt tgattagttc aggaaatatc acaaatgaaa aagcagataa
    31261 agatgaaaat tcaaacaaaa ataataaaga taaaaatgaa gacaaatcta attctaaaag
    31321 taataaagat aagtcatcag aggacaaatc gtcagataat aaaaatgaaa ttcaaaaaaa
    31381 caaaaaactt ttaatttgta tagacccagg gcatcaagga aaaggagata gcaatttaga
    31441 accagtagct ccaggttctt cctctaaaaa agcaagagta tcttcaggaa cagagggtat
    31501 tgctacaaaa aagccagaat atgttttaaa cttagaagca tctcttgttt taaagagtat
    31561 attagaatct aaaggttata atgtaataat gactagagag acacatgatg taaatataag
    31621 taattcagaa agagcaatac ttgctaatga caaaaaagca gatatggttg taagaataca
    31681 tgcagatagt ttaaataatt cttcaaaaac tggagcatct atattgattc ctgaaaaaga
    31741 tggaaaatat acagctccta tatatgaaga aagtaataaa tgtgctgaat ttatcaaaca
    31801 gaatatggaa caatcaggta tacaaatcaa tggaatcgtt caaagaggtg atttgactgg
    31861 attcaactgg tcaaaagtac cagctgtatt agtagaaatg ggatttatga gtaactataa
    31921 tgaagaccaa atgatgtcaa atccagacta ccaaagaaaa atgatgcagt gtatagctga
    31981 tggattggat gcgtatttta aataagatat gaatagagaa aaagttaggt tggtattatt
    32041 ttcctaattt ttatctctat tttttattgt acataacaca aagaagaagt ttattttagg
    32101 ttaaattgtc gtaaatataa ctaaaaatat tgggaatact tgatttaagt ttaaaaagaa
    32161 tatattatag tatagaatgt gtaaaatttt tttgagaggt gttgaaatgc tagtagtaga
    32221 aaatgtgagt catggatttg gtgcgagaac aatattagaa aatgtatcct ttagacttag
    32281 aaaaggtgaa catattgcac tagttggtgc taatggagaa ggaaaatcga gttttttaaa
    32341 tataataaca aagaagctta tgccagatgc tggaaatata aaatggtctt caagagctac
    32401 agtaggttac ttagaccaac atacggtatt aagcaaggga aaaactataa gagaagtgct
    32461 tagagaggct tttaagcata tgtttgactt agagcaagaa atgattgcta tgtatgacaa
    32521 aatgggagaa gctagtgatg atgaaatgag taagcttctt gaagaaacag cagagataca
    32581 aactatactt gaaaatagtg gtttttatat gatagatgca aagatacaag aagttgcaaa
    32641 tggtcttggt cttggagaaa ttggtcttga taaagatgta actgacttaa gtggagggca
    32701 aagaacaaaa gtacttctta ctaaacttct acttgaaaat ccaactattc ttatattgga
    32761 tgagcctaca aactatttag acgaagagca tataacatgg cttactaagt atcttcaaga
    32821 gtatgagaat agttttgtct tagtttctca tgatattgaa tttataaata atacatgtaa
    32881 tgtaatatat catatggaaa atggagagtt aaatagatat aaaggaaatt atgatgaatt
    32941 tgtaagactt aatgatataa agaaacgtca agaagaacaa gcttatgata aacaagttga
    33001 agaaagaaaa agactagagg attttgtagc tagaaataaa gctagagtag caactagagg
    33061 aatggctaac agtagacaaa agcaacttga taagatggaa atattagaaa gaccaaaaga
    33121 aaaaataaaa cctacttttg cttttaaaga tgctagagca gctagtaaaa taatttttga
    33181 aacagaagat ttagttttag ggtatgatga agcattgaca aaaccactta atttccattt
    33241 agaaagagga aaaaagattg ccttaaaagg aatgaatggt attggaaaat ctactctatt
    33301 aaaaacttta cttggaataa taaaaccatt tgaaggaaat gttaaattag gtgactattt
    33361 ggaagttgga tattttgaac aagagagttc aagagaaaat agtaatacac ctatggatga
    33421 agtttggagt gaatttccag ggcttacaaa ctttgaagtt agacaggctc ttgcaaaatg
    33481 tggacttaca aatgaacata taacgagtca aatgagagta ttaagtggtg gagaagctgc
    33541 taaggttaga ctttgcaaag taatgttaaa aaatataaat ttcttagtat tagatgagcc
    33601 tacaaatcat ttagatgttg aggcaaaaga tgaattgaag aaggctatca aagagtttaa
    33661 gggaacagtt cttttagtat gtcatgagcc agaattttat tcagaaattg ttgatgatgt
    33721 atggaatata gaagatttta caactaaaat cgtgtagtga tttaacttat tgctgggggg
    33781 atttcatgaa aaagtttcta aatgtacttt tttcaatttg tattagtatt gttataatag
    33841 taggtgttat taattttact gttggattta aacaacttta ttattttgac attgattact
    33901 taaatatatc agagttatct ggtttatcta aagatgatat aaaattgaac tacgattatc
    33961 taattgatta taacttaaat aagaatgtgt ctgagttcaa attaccaaca ttaaaatctt
    34021 ctccacaagg gaagatacat tttgaagaag tcaggaatat atttcaaaat ataaataaat
    34081 tagctaaatt attattggta gtttctttag taggaattat attgagtgta aaaaataaaa
    34141 atataaaaat cttaaaaact acatcaataa cacttataat tatgccatta ttattaacag
    34201 ttccaatttt attaaatttt gaaaagtcat ttattatttt tcataaatta ttatttagaa
    34261 atgattattg gatatttaat cccgatttag acccagttat aaatatattg ccagaggaat
    34321 ttttttttca ctctggaatg atgattttaa tattaatttt gttagtaagt atagtactgt
    34381 ttgtaatgta taaattatgt aaatctttat caataaaaat atttcaatgt taaatagagg
    34441 gatattttta tttccaaaat aagataataa aaaaggatta gattaaaagt tatacaataa
    34501 aaatagctgt gcaataatat ttagactatg aaagtagtta aaaaatattt atgcacagct
    34561 atttataata gaatttactt tttactagtg attttaacta aatcttgaaa tttactcata
    34621 atgtaattgt aattatcttt tttatgaggt aatatacaac tactgcaatc tttgatacct
    34681 ttatctgtat acttaaagtt tccaccacag ttttctccta aagcatacaa aggacaatag
    34741 caaaatagac agttaaactc ttctggttta ttagttttat gacaagggaa aaattcgcaa
    34801 tctttgtgat taaaaaactt ataattttcg cccatatttt cctcctaatt aaataaaatt
    34861 taaatttttt atactatata agattttggt gataatataa ttatactaaa taattttatg
    34921 aatagtcgat aatatagtat tattaatcat agtattaatg gtataattag tcaacagaaa
    34981 aataatgtaa aaataatgta agtgtatttt gtaattagaa tatgttttat aacaaaaaat
    35041 gaggtgatta agtgaaagaa attcaagaaa aagcacttct tgtaggtctg aatttgacta
    35101 caatagtgaa aaaaaatgat gatatagaca ctaatgaatc tatggaagaa ttaaaagaac
    35161 taacaaaagc tgctggggca gaagttgtag gtagcttaat tcaaaataaa cactctgtag
    35221 atgcagctta ttatatagga aaaggtaaag tagaagaaat aagagcctat agtgactctt
    35281 tagatgctac tttagtaatt tttaatgatg aattatctgg tgctcaaatc agaaatatag
    35341 agaatgttgt tggaagaaaa gtaatagata gaactacttt aattttagat atatttgctc
    35401 aaagggcact tagcaaagaa ggtaaattac aagttgaatt agcacaatta aaatatagat
    35461 tgccacgact ttatggaatg ggtggtgaga tgagtagaac aggtgcaggg attggtacta
    35521 gaggtcctgg agaacaaaaa ctagaaatag ataagagaca tatacttaat aaagcagcag
    35581 atataagacg tgaacttaaa gaagtaaaaa agaatagaga gacacagaga gttaagcgtt
    35641 taaagtcaaa tataccgatt gtagcacttg ttgggtatac aaatgcagga aaatctaccc
    35701 tgttgaacga attaataaag acacacaagg attatgaaca agaaaaagaa gtttttgtaa
    35761 aagatatgct ttttgcaact ttagatgtaa ccttgagaaa ggctcttttg ccgaataaaa
    35821 aagaattttt agtagtagat actgttggat ttgtaagtaa acttccccat gatttagtag
    35881 aagcgtttaa ggcaacattg gaagaagtac agtatgcaga tttaatctta catgtaattg
    35941 atgcaacaaa tactagttat gaattgcaaa aaagtacgac tgaaggtgta ttaaaagaac
    36001 ttggtgtaaa tgataaaaaa catatacttg tatataataa agtggacaag ctagaattgg
    36061 atatataccc taaaagtcaa gaagatattg tgtatatttc tgcaaaacaa ggcataaata
    36121 tggataagtt attaaatatg atagaaattg ctttaatgga aaatacttat tcagtaagtt
    36181 tgatgttacc ttatgagaga ggtgatatat ttagtagaat aaaagataaa tataatgtgg
    36241 agaattttga gtatggggaa agtggtataa cgctagatgt agatttagat gaagaagatt
    36301 ttaatatcta tagagagtac atactagaaa aataggttga atatggatat aaactgggaa
    36361 aatatagata atcttgaaga ttattttata acctatcttc tttataaaga atctaaaaca
    36421 gtatctcaaa ttagtaaaat tagaaatatt tcaagtactg aagcaagtga gcaacttata
    36481 caagcaaagt taaaaataaa ggaaatgcaa aaagatgatt ttgaggcatc taaggatatt
    36541 ttggataaat ttctagaact agataaaatt aagagacttg attttatgga tagcttagat
    36601 gacgaaaaaa tggtatactt taagagaaag gttttcaaaa gaatccttgt agaaaaaaat
    36661 gctgaagatt taattgtttt aatttgggcg acaggtgagc taaaagatga taggtttttg
    36721 aaattgcttc atcagctcac aaaccacaga cactcagata ttagaagaat aacttattca
    36781 gcaatcagaa agattgaatc accaagtagt agagaagtac tgcaaaaagg tctctacgac
    36841 aaaaatgcac agactaggca gtactgtgca aaagctcttt caaaattggg agatgaaaac
    36901 agtttaaaga ttttacagca gttgaaagac aagaataaga attttgaaaa agaatatgtg
    36961 cttagagctt atgacgaagc cattaagtca ttggaaaatg caaaaaattt gaaaaagtaa
    37021 ttttttatta aagcaatttg tttgcttaat gatgtatttc taaagtttaa caaggtaata
    37081 aataaattaa tgggaggggt ttcaaatgat agtaagacgt tgtgcaggtg gagtagtgtt
    37141 ttatgctaat aaagtactta ttgtaaaaaa tgataggggt gaatggacac ttccaaaagg
    37201 aaagatacta ggagggggac ttccatatga gagtgctgtt caaagagtta aagtagaaac
    37261 tggcatagat gctaaaatga tagatgtggc tggcgatact atgtatgaat ttttctcaag
    37321 aagtagacaa caagaagttt gtaatgcaat aatgtggtat gttatggaag cttgtaacac
    37381 tgattgtgta cttgctcctg aatttcaaga aggtggattt tataaagtaa aggatgcttt
    37441 agaaatgtta tcacatcata aagagcaagc tttagtagaa gtatcttata aaaagtttaa
    37501 ggaattaaag aaattagttt cagagggcga tgatgttcca gcaaattaat tgtgaattta
    37561 gaggattctg aggaagggat agccccttcc ttttttaatt gaagcagttt taagcgtaaa
    37621 ttatatagtc tctttaaact atgatttatc aatttagaga tttagtagtt tatatttaaa
    37681 atcagtaaga tatatttaaa ataaaaatta aaaagtatac aattttatta tataattgtc
    37741 ttatgatgtt gattaaagaa ttattaaaag tccatttatt tttaaataga ataattttat
    37801 aaatatatat ttgatgtgta tattagaaaa tgattaaaat aggaggaaat acaatgagca
    37861 attacaggac attacatgaa tttggaacgg atgaaataac gattgaaaag tctgttttta
    37921 ttggatatgc taagcctata aagagtgaag aagaagcatt agagtttata aatgaaataa
    37981 agaaaaagca taaagatgca actcacaatg tgtgggctta tactgtaggt aaaaatatga
    38041 atatacaaag atatagtgat gatggagaac cacaaggaac agctgggata cctacattag
    38101 aggttataaa aaaagaagat ttgagagatg tagcggttgt tgttactagg tattttggag
    38161 gaacaaaatt aggtgcaggt ggtctagtta gagcttatac aaaaggtgct aaactgggac
    38221 ttgaagcagg taagataatt tataaggtaa tgtatcaaga agttaaggtt aagatagatt
    38281 atactcaact tggaaaagtg caaaatgagt taatgaattt ggggtatttt ataaaagata
    38341 ctgtatatga ggataatgtt gaaatagtag tatattcaag attagaagat gtagagaaat
    38401 tatcagaaaa aatgattgat ataacaagtg gaacaggaaa aatagtttta ggagaggaat
    38461 tttatttgtc tgaacaaaat ggagaaattt taatataatc taaaaggtta ttagaatagt
    38521 taatacctca aatagccaat tagtattttt aagtgaaaag ccattaaatt gatttaatct
    38581 aaatcaattt aatggctttt tatcggattt tgcacagaat ccttttttta cttcaaataa
    38641 accgactaaa agtaaaaata tcccaaatat tttttttaat atatctgaag acagataatt
    38701 agctaatagt gaaccaaata cagctcctaa aaccccaaac acagctatag gtataaccaa
    38761 tttaaaaatt acatttttat tttttatatg tatagcaagt gctataagtg tcatagggat
    38821 agatgaaagt aaatttacgc tttgtgctat tttagtgtct atgccagcaa gtaaaacgag
    38881 tgcaggtata aggattgttc ctccacccat tcccattcct ccaataattc ctgcaaaaaa
    38941 tccaattaga gcaaataaca ttaaaacacc atccttaatg ctgcaattat cataattatt
    39001 ccaaaagaaa ttctaagaaa ctttccagta accttattta gtaatttagc tcctataata
    39061 ccaccaagaa tacttccaac tgcaacttta attgttaagt taacatcata agtaccttta
    39121 gatacatata aaacagaact tgctgtcgtt aagaatatta ttatagaaag agcagttgca
    39181 tgagatttat gttcttctac cttaacgatg tcatttaata ttggaactaa aagagtacct
    39241 cctccagaac caaaaactcc atttataaat cctgtaaaaa ctccaattat cgtatttttt
    39301 aagttaaaat caaagtattt ttgctttaaa tcatcagttt ttttcataaa aatcaccttc
    39361 tgaaatagtt ttaccaaaat aggcaaatta tatttatata aaataagatt aaatataatc
    39421 tttcatgttt gtttaatttt gcataaaaaa aaacatatta aaacaacata ttaatatatg
    39481 gtataatata ttaaaacaaa gtagcaaatt tgagaggaga taacaatgtc aaatataaaa
    39541 atacaaatag acaaaactgt agaatggctt ataaataagg ttaatgaggc aaatgcaaaa
    39601 ggattaattg ttggtgtatc tggaggaatt gattcggcag tagttgctaa tttaattaaa
    39661 aaggcatttc cagaaaactc tatgggagtt ataatgagca taaaaagtaa tcctcaagat
    39721 agagaagatg cacttaaggt tatagaggga tgtgatatag aataccttga tttagacctt
    39781 atagaaccac aaagtgctat attagacatg gtagtaggaa atttaaaaga taaacattta
    39841 tatagagaag aatatttaaa gatgacagat gcaaacttaa gagcaagagt aagaatgagt
    39901 acaatttata caattgctaa caatctagga tatctggttg ttggtacaga caatgctgca
    39961 gaaatacaca caggatattt tactaaattt ggtgatggtg gagttgatat tttacctatt
    40021 gcaaatttaa ctaaaggaga ggtgtatgaa tgggcaaaag agcttggtgt tcatgaagat
    40081 ttaataaaca aagctccttc agcaggtctt tgggaaggtc aaacagatga agatgaaatg
    40141 ggaactactt acaatatgat agatgctgta ttagaaggta gattggatga agttcctaaa
    40201 agagaccaag agataattga aagacttcat agattaagtg aacacaagag aaaaacgcct
    40261 gcacaacctc ctaagttcta atttactatt tataagattt gtgataaaat ttacaagtga
    40321 tgaaaattag aataattaat tgtacgtatt aaggagtgga aatatgggac gtataggtaa
    40381 tataattaat agaaaaggta aacaagatgc tcaaagagca aagatattta ctaaacatgc
    40441 tagagcaata gcagttgcag ctaaagaagg tggagcagac ccagagtaca atgcagcgtt
    40501 aaaaacagct atagaaaaag ctaaggcaga taatatgcca aatgataata tagatagagc
    40561 tatcgctaaa ggtgctggag caggtgctgg agaagactat gaaactatag tttatgaagg
    40621 atatggacct ggtggagttg ctgttatagt agaaacttta actgacaaca aaaacagaac
    40681 tgctggtaac gtaagatact attttgacaa aaacggagga aacttaggaa ctagtggatg
    40741 tgtgtctttt atgtttgata aaaaaggaca aatattagtt ggtttaggag atggagtttc
    40801 agaagaagaa ttgatggatg ttgcattaga agcaggagct gaagatttca taacagaaga
    40861 agatggttat gaaataataa ctacaccaga agatttttct agtgttcgtg atgagttaaa
    40921 agctaaagga tatgagttta tatctgctga tgtgaagatg atacctcaaa ctacaactgt
    40981 attgactgaa gaatctcatt taaaaatgat gaataaatta gttgatatgc ttgaagaaga
    41041 tgatgatgtt caagatatat atcataactg ggaagtagaa taaatagtat aagcatattg
    41101 aaatttataa gtatttaatc aattttaaca tgtgataaat tttatagaat aagaaacact
    41161 aaaatagaca tacgcacctc taacctatat ttgcataata atatgtaagc ataggtaagg
    41221 ggtgttttta tatttatagg ttaagaaatt taaagtaaat tttgagctgg actcgattgt
    41281 ctataaataa ttgatgggta tataacttgt tgctgaatac catttatacg cccagttact
    41341 gtatcaataa tcatcctaag actacgttct gctgtctctt ccatttttaa atctataact
    41401 gtcaaaggag gaatacttct tgccattagt cgtgaaggtc cattacttgc tgcaaatatt
    41461 tgaatatcct ctccaattac aattcccgat tcatgaaatg cattcatcat accaagagct
    41521 accacatcat gattacaaaa aattactttt tttagtgaat tttttgcaag cattttttga
    41581 gcaatatcat atccactatc tattttatta gaacaataat atatagaatc tgatagatgt
    41641 attccatgtt ctttacatgt ttttaaaaaa gatttacccc ttaaagtcat acatgtaaag
    41701 gaagttgggt tgaatacaac agcaatatca tttttaccat tttgaatagc atgtaaagct
    41761 gctatacgac cagtttcctc attatcaata gatacacttg aaaaaccagg tatttcacga
    41821 tttacaacaa ctacaggaat tttaggttta ttttttacta gatattctat atcatcagca
    41881 ttgatacctg ttaaaacaat tccatcataa taattatttg caaaaaagta ttcatcatca
    41941 catagatgac caactttgta aggtcgtatg atgatattta tgtttaaatg ttctaaagaa
    42001 attatgtggt ttattgcttg aagtatattg gttgatgcca actcaaatcc ctcatcctgc
    42061 caataaaaag ctattttaat attattatgt ttaataggag tagagcgttt atatccaagc
    42121 ttatcagctg aatttaatat aagctcttgt gtatgtagcg gaatcctgcg ttcatttcct
    42181 ttaccactta agacgtacga gacagttgct gaagaaagac cacagtcttt tgcaatatct
    42241 ttgattgttg ccatgataaa atcctcctta aatagttgct taaatttgct tataccaata
    42301 atcttaacat atattcaact aaagaacaat attctacaag gtgcatattt tacaggatta
    42361 gaataaataa attaaaaaaa aacttcttac ttatgttgac ataatttagt ttataggatt
    42421 ataatatgct taaataagct tatgattaac ttaaattaag caaagttaag caggaacatg
    42481 caatgctagc ttgcaatgtg actgtaaagg gggaaaaggt atgagtaagg taaatatatt
    42541 tgaagttggt cctagagatg gatttcaaaa cctgaaagag tttttagaaa ctgataaaaa
    42601 gcttaagatt attgatggtc ttattgcttc agggattaaa caacttgaaa ttagttcatt
    42661 tgtaagccca aaagcaatac ctcagatgaa agatgcaaaa gaagtagcaa cttattgtgt
    42721 agaaaaatat cctgatgtga aactttatgc attagttcca aatttatacg gtgctaaagt
    42781 tgcatgggag tgtggtataa gagatatatc ctatgttata tctttgagtg aaactcataa
    42841 taaaaaaaat ataaatcgta cccatgaaga gtctattgat gagcttaaaa aaataatgaa
    42901 tacttatcca gacatgaata tatgtattgg aatggctact gtatttggat gtccttttga
    42961 aggtttacca aaaattgaag atgccataag atttgctaaa cgcctttggg aaaacggtat
    43021 cagggagata aatctagcag atacaatagg gattgctgac cctaagcaag taagagaaac
    43081 tattagtgca ttagttgaag ctttaccaga gtgcagatgg caagtacata ttcatgatac
    43141 tagaaatatg ggaatggtta atactcttgt ggctattgaa tctggaatta ctactgttca
    43201 gtctacactt ggaggattag gaggatgccc atttgctcct ggagcatctg gcaatactgc
    43261 aactgaagat ttagtatata tgcttgaacg tatggggtat gatacaggag ttgattttgt
    43321 taaacttctt gaattatcaa agtatcagaa gagttttgta aatggagtat atagtggtca
    43381 tcatataaat ataaagtctg atagttgtaa ttgttagttc tattgattaa tcgattaaaa
    43441 aaatatgttg attaaaaaaa tatgctgatt ggtaaaatag atttattgat aaaaaatata
    43501 aattataaaa tacattatct aataaaacaa ataaaaaaat tgagggggat tagtatggat
    43561 attatagctt tacttttatt tttaggagtt attattattg catttgtacg taagaataat
    43621 gcaggtattt tggctctagc tattggtgtc atagctgtta gaatttttgg aatggatgat
    43681 aaagaacttt atggagctat aagcaactca atgtttacta cacttgttgg tataacacta
    43741 ctctttgcaa tagtgaactc aacaggagca ttaaagcttg ttgcagaaaa aattgtagct
    43801 gcttctggta aacgtgtttg gcttatacct atagcagttt ttatagcagg atttgttgtt
    43861 gctggtgttg gacctggggc aattccagca cttgcaatta tcccagcaat ggctgttcct
    43921 gtagccataa cagttggtta taatcctgta atgcttgcac ttataggtga atgtggatta
    43981 atggcaggtc gtatgactcc tattactcca gaaggtcaaa ttataacaac cgttgcagaa
    44041 ggggttggaa ttgaaaatgt tatgcctact atcttagcct gtcaaactct ttctacaatt
    44101 gtattttcaa tagtattgtt tataattttc aaaggatata aacttaaaaa acctataaat
    44161 gttatagata gtaagcaaat agaaaaattc aatataaagc agataatttc tctaataagc
    44221 atagtagtta tgattgcttt tatcataatt tttgatatga atgttgggct tgcagctttt
    44281 gcagtttcag ctgtacttat ttttttcaat attgctgatg aaggagaatg tatcaaatca
    44341 attccatgga gcacgatagt aatggttctt ggagtaggtg caatgatgac aatcgtagat
    44401 gcagcaggag gtattgactt gatgagtaat gcattatcat cactgatgaa tagtaaaaca
    44461 gctactccaa ttatgagtat ttcagcagga cttatgtcta tggttagttc tgctttagca
    44521 gtagtttatc caactatgat gcctatgtgt gttgatatag ctaaggcagt tggaggagta
    44581 gacccactag cacttattgc tgcagttggt gttggaggtt ctcttgctgg tgtaagccca
    44641 ctttctactg gtggggcatt gattttagca gctatgggtt caagtaagaa agactttaat
    44701 aaggaagaac aaaataaggt ttttgtacag cttttcatta tgagtgcagt tggcttattg
    44761 gttattgcag tagtatcaat attatcattt aatgcaataa cacatttaat gaactaatta
    44821 gaataactga aaataaatca ttaaatttaa cttttaatat taatcaatat aatataattt
    44881 ggaggggaag ttatgaaaaa aggagcatta agcaatataa aggtacttga ccttacaaga
    44941 gttcttgcag gtccatattg tacaatgatg ttggcggatt ttggagctga tgttataaaa
    45001 atagagatgc caagaaaagg tgatgataca agaggttttg gaccttttgt aaatggagag
    45061 agtttatact atgcaaatat aaatagaaat aaaaaaggta tcactctaaa ccttaaatca
    45121 gaagaaggaa aaaatatatt tttagaaatg gtaaaacatg ctgatgttgt agtagaaaat
    45181 tacagaccag gtgtaatgga aaagttaggt ctgggttatg atgagttggc taaagttaac
    45241 aatcaaataa tttatggagc tgtatcagga tttggatgtt atggaccata ttcagaacgt
    45301 ccaggttatg atattattgc acaggcaatg ggtggtctta tgagtataac agggcaagaa
    45361 ggaggagaac caacgagagt tggtaatgct atgggtgatg tactaggtgg aatgaattta
    45421 actattggta tactcacagc actcaacgct agaaaaataa taggaaaagg acaaagagta
    45481 gatgtttccc tcgttgattc tgttgtatcg tctctcgaaa ctggtataca gagatacttt
    45541 gattcaggac aacctgaact tatgggtaat agatatgctt cagcctatcc ttatgactct
    45601 tttaaggcaa gtgatggaag ttttgtaata ggctgtggta atgacaaact ttttgaaaag
    45661 ttatgtaaaa aagttctttt tagagaagac cttttaatag atgagagatt taaaacaaat
    45721 cttaatcgtt gtgaacatta caaggctctt aaaccagaaa tagaaaaatg gtctgttaag
    45781 catacaataa aagaagcagt tgacttaata tcagaggctg gagttcctgc tgctcctatc
    45841 tataatcttg attgtgttac aacagatgaa catatagcaa aagcaagaga aatgattgta
    45901 gatattagtc atcctattat aggaaatatg aaagtcaatg gaaatccagt taagttgatg
    45961 acaacaaaag ctaaaattga tatgccagca ccatctctag gggaaagtaa cgaggagatt
    46021 tataatggtt ggcttggttt tgatagtgat aaaataaaag atttaaaaga aaatggagtt
    46081 atttgattaa aaaatagcta aacacacttg tgactttagt catgggaggt tcagttagaa
    46141 taatatcaaa aaatattaaa tcaatactgt aaatcaaata tagaattgtc agaagcattt
    46201 aagatgggaa aagctactta gacattgagt ctttgtggct tttcctattt tcattaagaa
    46261 ttttatatta tcagaataga tatgtactaa actaaagtat taacaattta aattaataga
    46321 aaataaacta cctaattatg ttgaataaag actactttag tgaaaataaa cttatagaga
    46381 tgctatttaa attattttaa tggaaatatc aaaaatgaga ctgcattctc aaaaatgaga
    46441 ctgcgttttt taagtatttt ctcgaaaatg agacaaaaat attgttttat gggttttatt
    46501 gaagaaaaat tcttctgtga attacaattt aatcaatttt aaagttgaaa attattaaaa
    46561 atttagtgaa atttatgtat atttcgttta ttttattaaa aataacaatt ttttactaaa
    46621 aataaagaac ttcaatggtg attggcatag tacttgctat tttatattaa caagaaatgt
    46681 agaaaaaata acaatgtata atggggggaa tatgatggaa tctgtaatgg aaaatttgaa
    46741 caatcttaag gtggagctta aggacaaagt ctgtgttatt actataaata gacctaaagc
    46801 tttaaatgct cttaatagtg acactcttag ggaactatca caagttattg atgtagtatc
    46861 agaaaatgag gcaatattag gagttattat tactggagaa ggtaaagttt ttgtagctgg
    46921 tgctgatata cgccagatgc aaaactataa aagtgaggaa ggcagaaaat atgcaggtta
    46981 tgctcaggga atttttgata aaattgaagc tctggagaaa acagtaatag cagcagttaa
    47041 tggatatgca ttaggtggtg gatgtgaact tgctatgagt tgtgatatta gaattgcatc
    47101 agaaaaggct atatttggac aacctgaagt taatttagga gttattccat gttttggtgg
    47161 aactcaaaga ttatcaagac ttgttggaac tggaatagct aaagagttaa tttttacggg
    47221 gagacaagta aatgcagaag aagctaaatc tattgggctt attaataaag tggttccaag
    47281 tgatttactt ttagaagagt ctatgaagat gatgaaccaa atagttgaaa aagcgccaat
    47341 agcaataaga tatgcaaaag ttgttattaa caaagggata gatatggatt taaagaatgc
    47401 tcttgaacta gagaaagata ttgcaggttt aacttttgct acaagagata agcaagaagg
    47461 aatgaatgca tttatagaaa agagaaagcc agtttttgaa aataagtagc tattataact
    47521 aaaattggaa caatgtagaa tatattcaaa atctaaattt cgtgaaaaaa tacatatagt
    47581 ttaattttaa aaggagttaa tttatgaata cgggagtaat tataagttta gtagggatta
    47641 tcatagctct atctcttcta gttgtaatgg ttatgaaggg aataaatatt tttattatag
    47701 caattgtatg ttcatcatta gttgctataa caggaagcct aaatgtgtat gatgcactta
    47761 aagtggatta tatgacaggg tttgttggat ttcttcaggc aaatttcttt attttcctaa
    47821 caggtacatt aatgggaaaa ataatggaga ttactggtgg agcaaaatct attgctaaga
    47881 tgattgtaag atggattggg aaggataaag cactactttc tattccaata gcttgtggaa
    47941 tattagccta tggtggagta agtgttttcg ttgtaagttt tgcagtgttt ccgatagctt
    48001 tagaaatttt taaagaagct gatttgccac gaagatttat accagcagct ttgacttttg
    48061 gatgctcaac ttttgctatg gttgcaccag gggcaccaca aattcagaat attgttccag
    48121 catcaacatt agggacagat attatggctg gagcagtaaa tggttttata tcatgtgcag
    48181 taatgtttat agttggaagt acaattttgt acaaaatggt ttcaaaagaa aaagccaatg
    48241 gtggtcattt tatagcacat gagtcagata tatttgatga agcagaagca actaattcta
    48301 agagagaaaa tggtcccaat ggtgtaattg ccttaattcc attgatagtg tcaattttaa
    48361 taattaatgt aaaagttaat ggaaaagcga tagtaccaat tgaggtggga gtatttattg
    48421 gagctttatt agtatattta ttgttaaata aatatcaaga taatactaaa atagttggac
    48481 atgttggtga tgcatgtaaa actacagtag tagcaatatg taatacttgt gctgtagttg
    48541 catttggttc agtagtaaaa tcagcagttg gttttgactt catagttaat gccatgacta
    48601 atattcctgg tcctcctatt gcaggggctg cagttggaac tacagttatt gcaggtattt
    48661 gtgggtcagc ttcaggtgga ctaggaattg cagctccact tcttggacca gtatttttag
    48721 ccaagggtgt ttccgctgca gcattaacta ggactatggc aatttcatca gcagcattag
    48781 attcacttcc acacaatgga tatattgtta ctgtaacaaa tggtctttgt aaagaaacac
    48841 ataaggatgc ctatatgcca atattctggg taactgtttt aaccccattt attggaacca
    48901 tagtagcagt cctactgttt acaatgttcc cgggattgcc ataagagaaa agataaaagg
    48961 tataaattat attttgatat tataaaatca attttcaaaa tatatacaat aaatttcatg
    49021 ttttaatact gtaaatatgt atttaaaata acaaattgac catataagga ggaattgaaa
    49081 gtgttaaata aaccattaga gggagttaag gttattgacc taacgtattt tgtagcaggt
    49141 ccagggactt ctaaaatatt agctgactgg ggtgctgacg ttattaaggt agagccaagc
    49201 tttggagacc caggaagaaa gacaggggca acaatgacaa tgccaataga tgattataat
    49261 aatccttttt acagcacata taattcaaat aaaagaggtt tgtctataaa tcttaagagt
    49321 gaaactggaa ttgaaattat ggataagctt ttaagcgaag caaacgtatt tgtttcaagt
    49381 tatagaacag gagcgttaaa aagactaggt cttgattatg aatcattaag taaaaagcat
    49441 ccacacctta tctggggtca gataaatggt tttggcgatt ttggacctgc taaggataat
    49501 gcaggatttg atacagttgc cttttgggca agaagtgggg ctatgcttga tatagcagaa
    49561 aaagatacaa gtccaataaa tccacctata gcctttggag atgcaacaac ttcttgtagt
    49621 ttatctggag gaatatgtgc agctttgtac cagcaagcta agactggcaa aggacaaaaa
    49681 gtaatggcat ctttatttgg gcaagcaata tggaatgcat catctttatt agcatctaca
    49741 cagtttagtg atgagtatcc aaaaactaga aaaaatgcta tttcaccagt aataaattct
    49801 tatcgttgta aggatggaaa gtggatattc ttaagtattt tagagcatga aagatatttt
    49861 gaggcacttt gtagattatt tggaagagaa gacttaataa aagaagagaa atttgcatct
    49921 tcagtagaaa gtaagaaaaa tgccacagaa cttattagta ttttggatgg tgaatttgca
    49981 aagtttactc aaaatgagat ggttgaaaaa cttactgctg ctgatatagc tcatgaaaaa
    50041 attcaacatg ttaatgatgt agtgactgat gaacaggcta ttgctaataa ctatatatat
    50101 gaacatacaa gtaaaaatgg gaataagaca atgcttgcat ctactccagt taaatttgga
    50161 aatattgaag ttaacatgac ttgtgatgct ccacttatag gagaacattc agatgagata
    50221 ttgagagaac ttggatacag tgattctgat atagaagctc taattgaatc tggaattgta
    50281 acaatgaata aagaagaatg tgaaatatgt taataaacat gtgaagtatg ttaataaata
    50341 ggagggaatt ttatggattt tagattaaca gaagcacaat taatgcttca aagagtagca
    50401 aaagaatttg cagagaatga aatagcacca atagctgctg aaacagacaa aacaggtatt
    50461 tttccaaggg agctttttag caaaatggct aaaataggat ttaatggaat tggaacacct
    50521 gtagagtata gtggttctgg tggggcagat atagaaaagg taattgttgt tactgagatt
    50581 gccaaaaaat gtgcagcatc tgcagcaata ttatcaatac acacaatata tgctcaagct
    50641 attttgaaat ttggtactga ggaacaaaag aaaaaatacc ttccaatgat ggctgaaggt
    50701 gggtgtgtag gtgcttttgc cttaaccgaa cctaatgctg gttcagatgc tgcgagagct
    50761 gcaacaactg caattattga tgaagaaact gatgaatatg ttttaaatgg aactaagtgt
    50821 tttatttctg gtggaggtca agcagaatca ttaataatat ttgcattgac agacccatca
    50881 aagggaataa agggaatgtc tgctatcatt gtcgacaaag gtactccagg tttttcaata
    50941 ggaaaaattg aagaaaaaat gggtattcat ggttcagaaa ctgcagagtt aatatttgat
    51001 aactgtagag ttccaaagtc taacttatta ggaaaagaag gtaaaggatt taatatagct
    51061 atgacttgtt tagatggagc aagaattgga gttggagctc aagctgtagg aattgctgaa
    51121 ggggctttag aagaaagtat caaatattct aaagaaagag tccagtttgg caagccaatt
    51181 tcagctttgc aaggtattca atggtatata gcagatatgg cgacaatggt ggaatcagca
    51241 aaattattag tatattatgc tgcagatttg aaagctagag gagaaaaaca cactaaagaa
    51301 gctgctatgg caaaatacaa tgcgtcacgt actgcaagag aggttacaaa tttagccctt
    51361 caaatccatg gtggatatgg atatatgaag gattatccat tagagagaat gtacagagat
    51421 gccaaaataa cagaaattta cgaaggtact tcagaaatac acaaagttgt tatttcaaga
    51481 gcagtactag gataggagga aaagaatgaa tatagttgtt tgcttaaagc aagttccaga
    51541 tactaatgaa gttaaaataa ataaagagac aggtactcta ataagagatg gtgtaccaag
    51601 tataatcaat ccagatgata gaaatgcttt agaagaagct ctaaaaatga aagatgaact
    51661 aggagcagtg attaaggtta taagcatggg acctcctcaa gctaaaagtg ctttaaaaga
    51721 agctttggca atgggagctg atgaagctta tttaatctca gatagagctt ttggtggttc
    51781 agatacttgg gctacatcta caattattgc tgctgctata gagaaggttg gaaagtatga
    51841 tgtaatattc tgcggaagac aagctataga tggagataca gctcaggttg gaccagaggt
    51901 tgcagaattt ttagggatac cacaagttac ttatgcgaaa gaagtaaagg ttcaagatga
    51961 caaattacta gtaactcgtt atacagagac aggggattat ttaatagaag caaagatgcc
    52021 agttttatta actgctataa aagagttaaa caatccaaga tatccaagtg tcaagggaat
    52081 cttagaagct tataataatg gagatgcaaa gattactgta ttaacacttg cagatttaga
    52141 tgttgataca actcaaattg gattaaaggg ttcacctaca aacgtttata agtcttttgt
    52201 accagttaaa gacaagcata atgaaataat agaaggtata aataaaaaag aaaaagctga
    52261 gaaactaata gaaatactat tcgatttgaa actagtatag gagtgttaag atgatgagag
    52321 caaaagttaa tcaaggtata aatttaaatg attataatgg tgtttgggta ataggagagc
    52381 aaagggaagg taaaattaat cctgttacga tagaacttat tggtgaagga agaaagcttg
    52441 ctgaccaatt aggaaaagag cttgcagttg tgatagctgg atatgaagta gagaaagaag
    52501 tgaaggaatt acttcactat agtgttgata aagtatatta catcaatgac cctcttctta
    52561 aagatttcac tactgatgga tatgcaattt caattgcaaa tttaatcgaa agaaaaaagc
    52621 cagaggttgt attggttggt gctacttcta taggaagaga tatagcgcct agaattgcag
    52681 gtaaggttgg aacaggtcta actgctgact gtacaaaact tgaaatagat tcaacagata
    52741 ataagttatt acaaacaaga ccagcatttg gtggaaattt aatggccact attgtttgtc
    52801 caaaaaatag accacagatg tcaacagttc gtccaggagt tatggcaaaa gctgtaagaa
    52861 acgaatcaga gactggaatt ttagaagttg ttactccaga acttactgaa aaaatgatta
    52921 gaactagatt agtagagata cttccacaag aaaagaaatc tgtaaatcta actgatgcta
    52981 gaataatagt atcaggggga agaggattaa aaagagcaga aggatttgag cttataaaag
    53041 aattggctga taaattgggg gcagagattg gtgcttcaag agcagcagta gattcagggt
    53101 ggatagaaca ttctcatcaa gtgggacaaa caggaactac tgttagacca gaactataca
    53161 ttgcatgtgg aatatctgga gcaatacaac atttagcagg tatgagtgat tctaaatata
    53221 tagttgctat aaataaagat gcaaaagccc ctatttttag tatatgtgac tatggaatag
    53281 taggagattt atatgaaatt atacctgaaa tgatagaatc attaaatagg taacttttag
    53341 aaaacattga atatgtagaa tgataagtct tataatattg tattgtaaga cttattattt
    53401 ttgctgaagg ttatagtggg gagatgaaac aatgaaagag cagtggtata aggatatatt
    53461 tgcaagagta ttatctatga ctgatgatgg ttttattgtt gtaaatacaa gtggagtaat
    53521 aatagatatt aatgataaat attgtgactt tttaggaaaa gaaagaaaag atataatagg
    53581 acaaaatata caaagtatta taccaaatac aaaaatgcta gatgttatga aaaataagta
    53641 ttgtgaagaa ggagctatac atcattattc aggtggaaat acaaaagaaa aaagtgtaat
    53701 agtaagtagg tcttatgtgg aaaatgacaa tggagaagta gttgcaggag tagctcaagt
    53761 taaatttaga ttgcaatcat ttgatgtagc taaaaagtta atgtcagaat atatggagct
    53821 ccaatattat aaagagcagt ttaaggataa ctgtggtttt gacaagctca taggtgaaaa
    53881 tagagacttc atagaactta agaaaacagg tgtgaaagct tctaaaacaa actttccagt
    53941 acttttaacg ggtgaaacag gcacaggtaa agaagttttt gctagagcaa ttcacaataa
    54001 tagcagtagg tcagataaac ctatggttag tataaattgc gctgcaatac cagaagaatt
    54061 attagagtca gagctatttg gctatgacga aggagctttt acaggagcaa aaaagggtgg
    54121 taaaaaaggt aaatttttag ttgcgaataa tggtacaatc tttttagacg agataggtga
    54181 catgcctttg accatgcaag caaaactttt aagagttctt caggaaagtg agatagaacc
    54241 agtgggaggt cttaaaacta taaagataga tgtaagagta atctctgcca caagaaagaa
    54301 tttaagtaaa atggttgaag agggattatt tagagaagac ctatactata gattaaatgt
    54361 aataaacatt catatgatgg aattgaagga caggcaagat gatattttat tgctagcaaa
    54421 ttatatatta aacaaattaa atgttgaata caaggaattg aaggttttaa gtgataaggt
    54481 taaaaattgt tttattaact atacttggcc gggaaatata agagaactac aaaatgtaat
    54541 aaaaagtgcc tatgctgtaa gtgatgatat ggtcattatg atgtgtgacc ttccatctaa
    54601 gatggataat atcagcagag tagctcaatg taatgtggat agcaattgtt caattcatga
    54661 aatggttgag aattatgaaa agagcttaat tattgatgtg ttaaggaagt ataattggaa
    54721 atgttctaag gcagcagagg ttatgggaat acacaagagt cttttatata agaaaataaa
    54781 aaagtatgaa attgaattaa ataattaaga taacttgaat taaggcaatg ctaaaaaagc
    54841 gcccttattc aaagcgaact gtataaactg ttttatgcag ttaaaacgtg taaaagtaga
    54901 tgtgaagtac taatgtcaat cattagtact tttttattat atttataatt actatctata
    54961 tttcagtatc ttttgatatc taagattatt atgtttaatt tagtatataa caaaaccctc
    55021 ttagttatgg acagtttttt atattttaac tgtctactaa gaggggatag tttagtttaa
    55081 atttagagta aattttatct agcatttata aaaaatattt tgaatagctt ttttgttatt
    55141 tagtcataat tttctacttc tttatcaagt tctttgccac aagaatcaca cttatatata
    55201 gcattgtatc cgtaatcata ttcatcaact attttctttt gtctaaatac accaccacac
    55261 tcacatagga aaccaatttt tataagtgta acgataaatt gtgattttat aaattttata
    55321 tcattgcatt tatcgttagt gtaaaatgta taaatataag agttatcgca ctcatctctt
    55381 aattcaaatc tttcaatata tgtgttattt tttaattcct caaattcttc tttagttaaa
    55441 tatgattttt gttgcaattc atgtaaacgc ttaatttggt ccattattta tatcctccca
    55501 ataattttag tattttaagc ttagataagg aatctaagtt ttattaaatt tatcccaagg
    55561 aattatttaa atcatattta gttttattaa ttacaacata tataaattac acgaaaataa
    55621 aactaattgt aaaaataata tcctgtgaaa acctaaacta ctaacccctt actaacccga
    55681 aaactaaaaa aagaaaatat atccaaatat aagtgatata taaataaaga tgtttcatat
    55741 aaatttaact ttaaatattc tgacaataat atatataaat atattatagt taaaatatac
    55801 cacatatttt gggtattgta tactggaatt agagtaatta atttattttt taacatacaa
    55861 atgattttat gaaaaaaaac aagactcaaa aatttttata ttctttgata gaataaaatt
    55921 gagagtaaat ttattgaatt ttataaaatt tataaggggt gagtctaaga tatgcatgaa
    55981 gataaaaatg atatatttga atcaatagat actgaggatt ttgataataa aacagaagaa
    56041 gaatgtttag agctagtaag aaaaaatgga ttgaatttaa tatacataaa aaatcaaaca
    56101 gaagagatat gtctagaggc tgttagacaa aattgtaatg caataaaatg tgttcagaat
    56161 cagacagaaa aaatatgtat agaagcagtt aaacaagatt ggagaatgtt agaatttgtg
    56221 gaagagccaa cagaagaaat ttgcatgttg gctattaacc aagatggaac agcattaaaa
    56281 tatatagaaa atcagacaga ggagttatgc ttaagagccg ttgaaaaaaa tggtgcagct
    56341 ttggagtatg taaaagaaca aacagaagaa atatgtatag aagcagttag aaacagcgaa
    56401 tttggattgg caagagtgaa aaatcaaaca gaaaaaatat gtatggaagc agttaagcat
    56461 tgtagctata atctaaaatg ggtagaaaat caaacagaag aaatatgtat ggaagcagtg
    56521 agacaaaatg ggcttgattt gaaatttgta aaaaatcaaa cagaaacaat ctgtttaaga
    56581 gcagtaagac aaaatggaat ggcattagaa tttgtaaagg aacagactgt tggtatatgc
    56641 ttaaaggcag taagacaata tggaatggca ttaaaatttg taaaagaaca aacagaagaa
    56701 atttgtacag aagctataaa acaagataaa agagcactta gttttgtaaa aggagataag
    56761 gaaaaataca aggctctata tgataataat gaaccatttg caaagagata tgttagaaat
    56821 gtaatagaaa aagaaaacag agcattgatt aaaaaaggag aagaaaatgc aaaaatcaaa
    56881 attgcaggaa aactttatga tagaggcatg tcttttgaag atatatcaga tatagttgag
    56941 attgaaataa gcaagttaaa agtgagttta ggtgtttttt aaagtaataa atgtaggtgt
    57001 tttttatggg aaatagttaa taaaaaaata atcgactagc tctttgtagg acagcaaaat
    57061 tagtgatata atttgatgta taataaatta tttttattag ataaggggga attaaagttg
    57121 aagattacag tattatacca aacaagaagt ggaaacacag aaagggtcgc taagctgata
    57181 gaagatggag ctaaaaaggt ggatggagta gatgtaaagc ttatgagact tgataatatt
    57241 gatttagatt atttaaatga aagtaaagca gtaatatttg gaacacctac ttatttagca
    57301 aatacaactt gggaagtaaa aaaatggttt gatgaagatt caaaaaaagt taatttagct
    57361 ggaaaattag gagctgtttt tgctacatgt gattatatat gtggaggtcc agatgttgcg
    57421 atacttacta tagtaggaca tttgatggtt aaagggatgc ttgtgtattc tggaggtggt
    57481 tctttaggaa agccatttat acatttagga catgtacatt caattgaagg tccagagtta
    57541 caagatgaga aggctataat atttggtgaa agaattgcta ctaaggcaaa agaactattt
    57601 gcttaatttc tatatgcata ataatgatta gagtaaattt agggttttaa tggagatttg
    57661 aagtaaaagt tataaaataa aaaattttcc ataaaattac tcaagatgaa ttataatata
    57721 attataaata aattatatta ttaaaatatt taaaatcaaa cgtcaatagc gagggaagtt
    57781 tatggtatgg catatagaat atgagatttt ttctgcaatt atagttattt ttttaatggt
    57841 atactttttt agaagtaaat ttatacctac tttacaaaac aaaatatatt gtgcactttt
    57901 aatattctca tttttattta taatttcaaa tattttaggt tcattttgtc taaataatat
    57961 agacaaaatt ccaattttta ttactttttt attgaatcag atatacttat tgttattgcc
    58021 aataccagca gcacttgtat cattttatgt tatggctatt atttatcaag atataaggta
    58081 tatgaaaaaa agattattat ttttatctat accacttata atttgtataa tcttatctat
    58141 tacaaatcct tttacgcata ttctatttgg attgtcaaaa gaaacaggtt atatacgagg
    58201 ttgtggatat gttgcaactt ttgcatcttt tttcttttat gcaatatatt cagcattttt
    58261 atcttttaaa tatagaaaag caatgcatga atcaaaaata tgggctatta gaggttttct
    58321 tatagtttca attgtggcaa ttatcttaca ggcaattttt ttacagtatc ttcttacagg
    58381 aactgcatgt gcatgtagtt tacttttgac atatctttct atgcagaatc gaggtcttat
    58441 tattgatgac cttactggtg tactcaatag acaatctttt attcaagagc tagatttgaa
    58501 tatcaatact gaacaatcag gatttattat tacaattgcg cttgatgatt ttaagtttat
    58561 gaatgaaact tttggaacaa aaaatggaga tattgcacta gaagaagttg gaaaatattt
    58621 gattcagata catgatgtaa accatgtata tagaataggg ggagatatat tttctattgt
    58681 tgtcaatagt caattaggta tagaaccaga tgatattatc agaaagatag aagaaagatt
    58741 taaaaagcct tggctagtag aagagataag ttttaattta gcaactagta ttgctgttgt
    58801 ttattaccca gaaaatgcag aaacgacaga agatgtaatt gttgctatag atttctctat
    58861 acatgaagca aaacgctctg agtcaaggcg agttgtttat gcagatgcgt ctataagtga
    58921 aaagataaag aagaaacatg ttattaaaaa ttgtttaaaa gaagcattaa aaaatgatgg
    58981 gtttgaagtg tactaccaac ctatattttc taatagcagg ggcaggttta cttcagcaga
    59041 ggcattactt aggctagaac acaaagagtt aggttttata cctcctgatg aatttattcc
    59101 aattgcagaa caaacaggat tgattaactc aattggatta gtagtctttg agaaggtatg
    59161 tagatttata gctagtgatg agtttgaaga tttaaaattg gataatatag ctgtgaatct
    59221 ttctgtagta caatgtatgc aaaaaaactt agctgatgat ttactttatc ttatgaataa
    59281 atataatgta tcaccaacta aatttaaact tgaaattact gagactgtgg ctatgggctc
    59341 ttttaatata attaaagaaa caatggaaag attaattgat ttaggtgtta agtttgcact
    59401 tgatgatttt ggaattgctt attctggagt tactaatatg ctttctttac cattttcagt
    59461 aattaagtta gataagagtt tgatttggtc tatgaatgaa gatagtaggc ataaacttac
    59521 agttgagacg attatagcac ttataaataa attgaatatg aaggctgtag cagaaggtgt
    59581 tgaaaccatt aagtgtgctg aagatttaat agctatggag tgtgaatatt tgcaagggta
    59641 ttatttttct aaaccagttc cagaagatgt ttttaaaaat ttgttgaaag aaaatacttt
    59701 tacaagttaa caccctttat ttttttaatt acaactttgt tcattgacac tgccagcgat
    59761 atattataaa attaacacaa taataaatat taaatttatt atacatatta ttaatattaa
    59821 ttaatggagt aaagatttat tatatatttt atttaattat cctaaagtga gaaaggaaga
    59881 tgtgacatga ataaaaagaa aatattagtg ccaattgatg ggacagaaag aagtatgcat
    59941 tctttggaat ttataaaagg aatatttaaa aaagatgaag ttgaagtaga aataatgaat
    60001 gtaaaagaac tagtatttat tgatggcata tccctggctg aagagataaa aaattctgaa
    60061 aatttaggaa gaagaatctt ggataaagca gcagagataa tgggagagta tgatgttaaa
    60121 gtacatttta cttttggata tccaggagat gagataatta gaaaagcaaa agaagataat
    60181 gtagatttta tagttatgac aaaatctact aaaaaaggtc ttacaagaat gataggttca
    60241 gtaacagcaa gtgtagttaa acaagcaaaa tgtatagtga tgattgtacc ggagtagaat
    60301 tagaaaggta tttgaaatat gaataaaaag atagtagcag tttgtgaaag tgaaagaagt
    60361 ttaaattctc ttaagacagc tgcaaatgat ttaggatttg atttagttta tgaaattcaa
    60421 gaaaatgata atataaaaaa tgaactttct atttatgata tagaagatgc atccatagtg
    60481 ttatttgtta caagtgattc tatagaaagc atagagaaga ttgatagatt tatagataga
    60541 gaattttatg aagttgatcc aaagtatata atagaggatg caaaatctat agtaagtgaa
    60601 attttaatag acttaaatta atcgtgggtg tcgcactaag aatagagcga cgccttttta
    60661 tatattttac acaagaaata aagaggttgt atcaaaatat agataagact ctttttcatt
    60721 gttgaaatga tgaaaatata tttgatttca tacaaaaaag agtacctcat aactaaaaag
    60781 ttcactttga gacactccat ttttatatgt tagttgcatt taaggtaaaa tataagttta
    60841 atcatgttga aataactgaa ttacatcttc taaatgattg tacattgatg tataacctaa
    60901 gtaagagtct ttactatcaa atgccatcat tatcttgtta tggtggctaa tcatatcctt
    60961 gagagaattt ctatatttaa aaccgaagta ttggttagaa gaaactgttt taggtattaa
    61021 ctcataatat tttataaaaa ttggattatg agaagctaaa attatctctt tgtgaaattg
    61081 caagtcagca tcataacatt cttctatcaa accatgagaa accttatcca attcctctat
    61141 tgactttagg taagtatatt ttattttttg aagttcttta gatgtagcat ttaaaattgc
    61201 tagtttagta gcttcgcttt cgataagttg tcttgctctt aaagattcta cataaaattc
    61261 ttgtatgtta tgatttttat agatttcacc atcatcaaat aggtcaactt ttttaaatcc
    61321 ttcaactata ggacttgaat aaggcacagc tctaagtatt ccttccttac agagtatatt
    61381 tatggcattt cttacaggta ttctacttat gttaaatagg tcagcaatct ttctctcact
    61441 tggtaattta ctattaattt taaaagttcc atttagaatg tttaatttaa tataatcaat
    61501 aattttttca gtggcattta agcttttcat aaaaactcct aaacatataa tttttttatg
    61561 attgtattat atcatagtta agagttaaat ctactttttt ataatatgta taagacagga
    61621 tagaggccaa aatagctata atagccaaga taaagtatcc atattgtatt gaagtatatt
    61681 ccgatatttt accaactatc attggaaata cagacattcc tatagcataa attgcttgaa
    61741 aaaaacccat tgcagtagat ttctgatgtt ttggtacatt tttcatagac tcgctagtaa
    61801 ggtaagaaag gagtatacct gtagatatac ctggtagtac ttgtagtaca aatattatat
    61861 taatattttt tattgttggg actaaaaagc aataggctga aactaaaata aaaactaaag
    61921 gaatccaaaa ttttggtcca tacttagtac aaaatttagt agaagcaaag ccagaagaag
    61981 caacagcaca caccatgtaa aatatagaag atagacctat gagggtagaa ctagaaccta
    62041 agtttttaag aatttgagta gtaaatgaca ttgttgtaga catttgaata ccctgttgaa
    62101 ttaatgccat aaaggaaaaa aatacaagtc ttttatcctt gcagatagat aaatattttt
    62161 taattgatat tttttcaggt attttttttg aattatgatt ttttatattt aaggctagaa
    62221 tcgttccaat aactgaagac aatacactca tgatacataa ggctgtcatt cctaattttt
    62281 cataaaataa agtactcata acaaatccaa tcaacattcc tagattgttt accaatatta
    62341 tcgtacttgt agctttttgt tgatgttctg tagaaaaaaa gttggtatag tgaaccatgt
    62401 aagaaatcca agttgatgat gatattccag ataaaatgtt agctataaga aaaccattgc
    62461 ctccaggaga aaagactctt ataagagatg ctaaaccagc aaagaaaatt ccagacagta
    62521 taaatatttt atgtttattt atagaatcag caaatactcc aacaggaagc cttaataaac
    62581 attgtgatat tccatatgca cctattatta taccaatcat atttgtagat acattacatg
    62641 cacttaaata tggattttgg aaaggtatat atacatattg tgaaaaccag aaaaatgtaa
    62701 caatagaaag taaaagtaat ttttgattag atattttttt catattatcc tccatatggt
    62761 atttttataa tgcaaataat ataccattta gattttttaa tcaagtactt tctctattaa
    62821 aaaaaattta aatatataat tattatttac aaaaaaatta tactttatag ttgaattaag
    62881 aaaacgctta tgatactata aagttaacaa atttgaatat ataacagtag acgtgttact
    62941 ggtaatgcag gcaagatcga atcaattttt atagattatc tatagagtac tatgggtata
    63001 atctatttat ttggttcgat ttttttgttt aattggccat aaaacaaaaa gcctatagtt
    63061 gaaaatggag gattttttat ggattataaa aatatagctc aagaaattct actaaatgta
    63121 ggaggaaaag agaatgtaaa tgaagtgact cattgtatga caagacttag atttaaagtc
    63181 aaaagcgctt ctaaagtgaa taaggataaa ttatctaaaa ctgaaggagt aataactgtt
    63241 gttgagagta tgggtcaaat acaagttgta attggaaata aagtaaaaaa agtatatgac
    63301 gaggttataa aaattgtacc tcaatcaaat aacgtaggta aaaagaatga aagtcaagaa
    63361 aaccaaggta taattaattc tatattatca gcagtagctg gtatatttac acctacaata
    63421 cctgctatag caggggttgg tatgattaaa ggtattttat cagttcttgc tatgtattat
    63481 atgaataaaa atggagtaga tataaaagaa acgcaaagct atattatctt aaatgctatg
    63541 gctgattcta tattctattt tatgcctatt atactaggat atactgcggc taaagtattt
    63601 aatgcaaata aaataatatc tatggtatta ggagctacac tttgttatcc aacttttact
    63661 gctttgatgg caggtgaaga atctgttaga tttttaggat tggcagtaac aaaagctacg
    63721 tatacatcat ctgttattcc aataattatt gctatatggg ctctttcata cgttgaaaaa
    63781 gtattagaaa agtatatacc tgagataatt aaaataataa tggttccaac tttatcattg
    63841 gttgtaatgt tacctgcaac attattttta tttggaccaa tcggaattta tataggaaat
    63901 gtcataaact tttcttataa gtatatttat gaattaagcc cagcattgtg tggagcattt
    63961 gtaggtgggt tatggtgtgt gttggttata tttggtgctc atagagcatt attaccaata
    64021 ggtataagtg atgttgctca aacaggaaga cagaatctat tggcgtttgc aggagctgca
    64081 aacttttcac aagcaggggc tgctctagga gtattcttta aaactaaaaa tcaaggacta
    64141 aaaacaattt ctatgtctgc aactataaca gctttatttg gtataactga acctgcaata
    64201 tacggtgcca atcttagatt aaaaaaacct atggtatgtg ccgtaatatg tggtgcattt
    64261 ggaggtgcga taatgggaat gggtggagct tatggtaatg catttgcaaa ccaaggtgtt
    64321 ttaactatac ctgtatatgc tgaagcaggt gcattaggtt tcttaagtta tctaggtggt
    64381 tgtgctatag cattttttgg ttcagctatt tcaacttatc tagttggatt tgaagatttg
    64441 gaagagtctt ctaataagga aaattcatct ataaaagtag aaacgaagga tggtgttatt
    64501 gatataactt cacctgtaga gggcgaatgt atagaattgt cagaagtaaa ggatgatgta
    64561 tttgcttcaa aagctatggg agaaggtata gctgtgttac ctacaaaagg agtaataaca
    64621 gcccctactg attgtgaagt agcttcttta tttccaacat tacatgcaat aggattaaaa
    64681 ttagataatg gagcagaaat gttaatacat gttggaatca atacagtaga gttaaatggt
    64741 aaatacttta caaaacatgt taatcaagga gatttagtga aaaaaggtga taaacttata
    64801 tcctttgata tagataaaat aaaaaaggct ggttatgatg taactacgcc agttatagta
    64861 aacaatacat ttgattttgg gcaagtagtt tcttgtaaat ctagttatgt ttcaaccaat
    64921 gataatataa tttcattagt attagctggt aattaagtta atttgactag agataagtaa
    64981 attgatttaa aaggaaataa gtaaatcaac aattaaatac atctaaaagt aagtttattg
    65041 caatgaattg ttaaagaaaa taattaatat ggagtaaatc tattgcaatg aagtaacaaa
    65101 gaaaataatt aatatagagt aagtttattg taatgaattg ttaaagaaaa taattaatat
    65161 agggtaaatc tatctcaatg aaataacaaa gaaaagagtt aatatagagt gaacttattg
    65221 caatgaatca acaaagaaaa taattaataa aaaggagaaa tatttatgaa tacaggattt
    65281 ccaaaagact ttttattggg agcatcatct tctgcatttc aagtggaagg agcttgggat
    65341 aaagacaata aaggaaaaac cgtagccgac tataattctt ttaaaaagtc tcatttacag
    65401 gcagatacta aagtcgcatc agacttttac cataattatg aagaagatat tgaattaatg
    65461 aaagaattag ggatgaaaac atatcgtttt tcaatttcat gggcaagaat aataccagat
    65521 ggtgaaggag agataaacca gaaaggttta gaattttata ataagataat agacaaacta
    65581 atagagtgtg atattgagcc attcgtaact ttataccatt ttgaccttcc atttaaatta
    65641 gtagagaaat ataatggttg ggaaagtaga gaaactgtct atgcttttga aagatttgct
    65701 aaaatatgct ttaagcattt tggagatagg gtaaagtatt ggcaacctca taatgaacag
    65761 aatttaattg ttagagtgga ggagagaatt aatatatatg atgaaacaga ttcatggaag
    65821 atagataaaa tgcgtgctca gatggattat aatctttgct tagcacatgc attagcagtc
    65881 aatgcatgtc atgagatgat aaaagaaagt aaaattggag cagcagtatc atcatctgta
    65941 acatatcctc ttacttctaa gccagaagat gtatatgcag ctagaatgaa tgataatttt
    66001 aaagtgtact atatgcttga tatgcatcat tatggagaat atccagggta ttatatgaag
    66061 tatcttgaaa aaagaaatat agttcctcac atggaagatg gggataaaga gatacttaaa
    66121 aaagctaaaa tggattttat agctgtaaat tattatagga caaattgtgc agaagcttta
    66181 cctgaagatt cacaacattc atttggatta agagaaggaa ctgttgattt tagtatgtat
    66241 ggactattta aaatgtcaat gaatcctaac ttagaggcct ctgagtatgg agcagcaata
    66301 gacccatcag gtcttagagt tgccttaaat gaatattggc aaagatatca cttacctgtt
    66361 ataataacag aaaatggtct aggagctaaa gatatattag aagatggaaa aattcatgat
    66421 gactatcgta tagactattt aagaagtcat ataaatgcat gtaaactagc tattgaagat
    66481 ggtgtagaga tgattggata ttgtccatgg tcatttacag accttttaag ttcttctcaa
    66541 ggttttaata agcgttatgg acttgtttat ataaatagaa ctgaccatga aattttagat
    66601 ttaaaaagaa tcaagaaaga tagtttttac tggtataaag aagttataga gaacaatgga
    66661 atagtaaaat aaacataaat atatattgag ggttttagta tgtacattac aaaggtatta
    66721 aataattcgt tgctacttgc aaaggatgat aatgatgaag aaataatatt gatggggaaa
    66781 ggcattggcc ataattataa ggccgggtct gagttaaata aaaaagatat agaaaagatt
    66841 tttgttcttc atgatgaaaa tataaaaaag agtattatac aattggcaac agaaatagat
    66901 gcagaatatt ttggtatagc tcaaatgata attgcatatg gaatagaaaa atataactta
    66961 aaacttatga accatatata tttggcctta actgaccaca ttgcctttgc agtgagacgt
    67021 tttaaagaag gtataatgat tgaaaatcac tatttgttcg aaatcaagga atttaatcca
    67081 aaagagtatg atataggaaa atatgctatt actgttttta aggaggttct tggtttagac
    67141 ctaccagaag aagagattgg taatatagca ggccatttta taaatgcaca acaagataat
    67201 ccttatagtg atagaaataa gagaagtgct aaaattgtaa atgctatttt gcaaatagtt
    67261 cattatcact tttctattgt atataataaa gagtcatttt attataggag atttgtaatg
    67321 catctaaagg ccttttcaca aagatttctg gctaatgaac catcaagaga aaaaatagat
    67381 tttatatatg agcaagttca aaaaaattgt aaggaagagt atgaatgtgt gaaaaaggta
    67441 ggagcttata tgtataagga atactccaga gaattaccaa gacaagagga gttatatttg
    67501 atgattcata ttcataagat tttaggagaa ttatgcgaaa atagttagaa tatcttaata
    67561 tgctagtaat attataaaaa attaaaaatt aactgcactt taaatatgaa taattgcatt
    67621 acttaagggg gttgtcttaa aattgatttt tttaattaaa tttgaagctc aactcctttt
    67681 ttaaaccttt atatcattac aactttaatg tttatacgcc tgtactttag atgtatatct
    67741 actttttaca tttctcaaca tgcaaaccta ccattttttg cagtatgtta attgaaataa
    67801 accattgagt taaccctaaa tttattctgg acttatagga atagttccaa agatacttta
    67861 aaatattttc tggaataatt gcttatttca catatgtttt attgtgatgt tttgatttaa
    67921 taaattcttc aactctgtat atagtaaatg tattatcatg tttgttttat tcaagcacac
    67981 ttataatacg cttgattttt tcacaatgat gaaatatact aatgggtgtt ataggtataa
    68041 gaatcgcatt acacttgaag aagtaagtga taaatgagat ataaatcctc atatgataaa
    68101 ctactatttc attgaggaac atattctaag tgatgtcaag atactacaat atgactaaat
    68161 tcctagtgat aaaaaagtct acgaatgagt gtagaaaggg gaactaagat gaataaagtt
    68221 ttaattatag atgatgataa agatctttgt attttgttaa aaaagagtat ttcaattgaa
    68281 cagattgaag caaactattg ccattctggg agagatggac tggttgaact ttcaaaacaa
    68341 gattatcagt tagtagttct agacgtgatg atgccaggta tggatggttt tgaaactatg
    68401 gaacaaatac gaaaatatag cagtattccc atcttaatgc tgacatcaaa aagcgataat
    68461 tacagcaaag tgcatggatt gcgagctggt gcagatgact atctaaccaa accatttgaa
    68521 attacagaat ttactgctcg tgtactgtct ttaatccgac gttacacccg ttttaatcca
    68581 aaaaatgagg agccacagca actttctttc aaaggtttgt tgattgacct tgaccagcat
    68641 acagttacta ccaatggcga acctatgttg cttccaccca aggaatttgg tgtacttctt
    68701 tactgtgcaa ggcatcaggg taagattttg acaaaacagc agatttatga agccgtgtgg
    68761 ggtgagccat atgtatatga tgacagcaat atcatggcta ttatcagtcg cctaagaaaa
    68821 aaaattgaac tagacccatc atctcccatc tatttgcaaa caataaaagg aattgggtat
    68881 caattcaaca cggaggtatg aaaatggatg aacaaacgat aattcttttc ttactcttgc
    68941 tgtcgattgg tctacttttt ctttccatat ttgctttttc caagcttggg catatttaca
    69001 agcgcctaaa agatatagag gagatactgg ctgatgtaca aattggagac gaaaatcgta
    69061 aaatactaat taagccatgt gatgttatgg ctccattggt ttatcagctt aatgagattg
    69121 tctacgatta tgaaaataag ttactttctc tgaaaaagtc ggataaagct agcaaacaac
    69181 ttatgacaag tttatctcat gatgttcgta caccattaac aactctgatt ggttatctgg
    69241 atgctgtaca cagtggtata gttatcgaac aagagcggga ggaatacctt gaaatcgcta
    69301 ggcgtagagc ctacgacctc aaggattaca ttgatgttct ttttgactgg tttcggttga
    69361 actctgatga atttacgctg tcaatagaat ctgtggaaat tgcagagttg tcacgcaata
    69421 ttttgaaaga ctggattcct atattccatg aaaagaaact gaattttgaa attgatattc
    69481 cagaaaatcg actaatggta aacctcgacc cagatggata ttcccgtgtg gtcaataatc
    69541 tggttcaaaa tgttcttgct cacagtaagg ctcggcaaat caaaattacc atgagtgagg
    69601 attccagaat ggtattactc cgtgttgagg atgatggtgt tgggattgcc agagaaaatt
    69661 taccacatat ttttgagcga ctgtataagt gtgataaagg acgttcagaa aaaggaagtg
    69721 gtcttggtct atctattgtc agtcaaatgg tggagcgaat gggtggtcag gtttccgtag
    69781 aaagtgagat tggaaagtat accgtattta cagtgagctt accattaata taaaattgtt
    69841 tttcccccat gtgacatgta tacacagggg gattttttgt aagttataaa gttgcaaggt
    69901 taatacaagg ttgttgcaag gttaatgtaa gattgaggtg gtatgataac tttaataaac
    69961 aaaggaggct tttattattt atgaataatt taattattga aacaaaaaat ctcactaagc
    70021 aatatggtgc tcaaaagagc gtttctaatt tgaatattca cgttcagaaa ggtcgcattt
    70081 acggattgct aggaagaaac ggtgcgggta agacgacaac tatgaaaatg ttattgggtc
    70141 taacaaaacc aactactgga gaaattaaaa tatttggtca ggacattcac aataacgaga
    70201 agaagcttct tcctcgaatt ggatgtttga ttgaatcacc agggttttat cctaatctga
    70261 caggaacaga aaatctcaaa atctttgcaa ggcttagagg aataccaaaa aaaaatgcag
    70321 tagaatcagc actggatgta gtcggtttgc caaacaatga caaaaagtta ttttctcaat
    70381 actctcttgg tatgaaacag aggttggcga ttgctcttgc cattatgcat gacccacaac
    70441 tgttgatttt ggacgagcct atcaatggac ttgatcctat tggtattgca gaagtaagaa
    70501 catttattcg tgatctctgc acagaacgag gtaaaactat tttgatttcc agtcacattc
    70561 tttctgaaat tgccttgttg gcagatgaca ttggcattat tgaccatggt attttgttgg
    70621 aggaagaaag tcttgcccaa ttagaagaaa aaaacagtaa atacatacat tttgctgtat
    70681 ctgatgcagc acaggcagca aggcttctgg aaacccaact taacctgaaa aatttcaaag
    70741 tagcagataa ttacaatatt atgctatatg atacagatgt ttctgttgca gaaataaatc
    70801 gtgctttcat tctaaacaac attgaggtat cagaatctca tttatgcgaa gatactcttg
    70861 aagattactt caagaaagta acagggggtg aaggaattgc ttgatataat ttcatgtgaa
    70921 ttttcaaaac tcaagcggtt aaaatttata ctgatttcta ttttaggtgc ttgcttattt
    70981 ccaattcccg caacaatttt gattgcaaag gataacttgc cctttgagca attgttcaaa
    71041 ttagttgtca attttggata ttttttgcta ttaccaattg tattaagtat tgttgctagc
    71101 caactatttt ttatagaaag agataatgat gtattaaaaa atcttgcaac agtgccagtg
    71161 ccaaaaggaa aactggctct ggcaaaattg gctgtgttgc tgtttatatc attgttctac
    71221 tctgttgcag ggttaggagc tactatcatt ggaggtttca ttgttggaat agtagagggg
    71281 gttgctgtaa aattaggaat gagcattgct tttggaatta tgttttttgt tactgtactt
    71341 cctgttgtgg tactcattgt atatttcaat cgcagctata ttttttctat tatactttct
    71401 tttgtatatg ctattttcaa ttttagtata tccttaaata ttatcaattt tgaaccaaat
    71461 aacccaatat taagtgtatt acctgctcct gttataatgc gttggtggat ggcattttgg
    71521 ggagatccca ctggcgaata cacggcactt agacagccat atttgctctc aactcctgct
    71581 tgtgtaggta ttttatgttt gataaccatt atagcagtcc tgctgatttg tatgatatac
    71641 aaaaagcagg agaattagga ggtatctatg cttgatataa ttactacaga atttcaaaaa
    71701 ataaaaagat ataatattct atggattggt gttgttgctg ttctgttttc agcactattg
    71761 gcagtttttc aggttgtaag ttcacacggc agtgaccctc taacgtatga gagctttgca
    71821 aacggagtta tctggaataa tttcagtctt agttttccat ttgggattac acttattgga
    71881 ggatatctta ttaaccgtga atatacagac caaaccttaa aaaacatcct aactgttcct
    71941 atttcattac gcaaattgct agtgggaaaa ttaattgcag ttggaggaat tactgtattg
    72001 ttaagtcttt tcagcttctt atgcacattt attttggggt tgttattttg taatatcaat
    72061 atatctgtta cactcgttgt aaaatcctta gttcagattt tgtctgttaa tctgtattgt
    72121 tatgttgctg ttttgccgat tattgcttat tttggtcgta aacaaaatgc atttctgaca
    72181 ggtgtaggga ttgcatttgt atacggtttt tgtggtgtgt ttgttgctgg aagaaatctg
    72241 acagactttt atccaatcac agcaggtctt ggtctagttg gatacaacaa tggtgctggt
    72301 actgtttatc agccacttat cggtgctatg actttgattg taattctaat cttgacaact
    72361 attctacttg tatttacacc taattatgat aaagttatga ccatatctaa gaaaaaaggg
    72421 ataaagcata aaaagtattc tcataaataa cataaatatt gtttctatta tttaagttgc
    72481 tagacagtga aaagaaaaaa tctgtcgtac agtggctata tgctcatgta ttcaagaagc
    72541 tacagttttg atttttcata actgtagctt ctttttgtat ttattaaatc acgactatca
    72601 taatacttgc aataggtata gcgacaagag agagtactgt catatgtgtt ttatatatta
    72661 cattaagtat attctaaaat atatgtttta aataatatat ttgaaaatag gaatatttaa
    72721 ataaaaaaaa taatattata tatagttgac aaaaattggc aaatgagata ctatataaat
    72781 atagaaatag taatcattac tattattaaa aagggaggaa ttaattatga acttaaaagg
    72841 aactaaaaca gaaaagaatt taatggcagg atttgcagga gagtcagaag caagaaataa
    72901 atatacatac tacgcttcaa aagcaagaaa agaaggttat aatcaaatag ctgctatatt
    72961 tgaagaaact gctaacaatg aaaaggaaca tgctaaatta tggtttaaac ttttacatga
    73021 tggtatgcct tcaacagagg aaaatttaaa ggatgcagca gcaggtgaaa actatgaatg
    73081 gactgatatg tatgcaaaat ttgctaaaga agctagagaa gaaggatttg acaagatagc
    73141 ttatttattt gaagctgttg gaaaaataga gaaagagcat gaagaaagat acttaaagct
    73201 tttagaaaac ttaaatgaag gaaaaatatt taaaagagat gaagaagttg tttggcaatg
    73261 tcaaaactgt ggtcatgtgt atgtaggtac tgaagcacca gaaaaatgcc cagtatgtga
    73321 ccatccaaaa gcatatttca atataaaagc tgaaaattat taaaaattat cattattaaa
    73381 aaggaatgtt aactatgaaa ttttctaaac aacgagaact gattttaaat gaaatattaa
    73441 ataatccggt tcatcctact gcggattacc tatatgaaaa cttaaaaaaa gataatccaa
    73501 atttaagctt aggaactgtg tatagaaatt tagctcagct aacggaacat ggctttataa
    73561 gaaaggttag tattccaggg tatccagata gatttgatgg tcgaatagat aatcactatc
    73621 atatcatatg tgaagtatgt ggagaggtat acgatttaga atccgaagtt cttaataatt
    73681 tacaagaatt aatatctgag gagacagaca taaaaataac atcttataac ataagtttta
    73741 aagggatttg taataattgt aaaaggtgta gccaagtagg ttagttttca aattctaaaa
    73801 ataattaatg aggtgagttt atgtgtagtg aacaaaaatt ttttatatgt gagacttgtg
    73861 gaaaccttgt aggaatgata caaagtggtg gtgtacctat tttctgttgt ggaaaaccta
    73921 tgaaggaact tgttcctaat acaacagatg cagcagttga aaaacatgta cctgtaattg
    73981 aagtggatgg aaataatgtt actgttaaag taagtagcac aactcatcca atgactaaag
    74041 aacatcatat agcatgggtg tatcttatga ctgaacaagg tggtcaacgc aaatgtctag
    74101 cagtagatgg agaacctgta gttaaatttg ctttgaatga tgatgataaa gtgatttctg
    74161 cctatgctta ctgtaattta catggattat ggaaggctga actgtaatat ttaaataaat
    74221 tgagtcaaaa aggaggctat aaatgtattt tcatacaaat agcctcctat aaatttatat
    74281 aaattcaagt tttaattttg tttaatgtca atataatata aggagaaaat aatatgtcaa
    74341 tttataaatg tagtgtttgt ggatatattt atgatgaatc taagaatgat aaaacatggg
    74401 atgaattaag tgaagattgg gaatgccctg tatgtacaaa aggtcgtagt tattttggaa
    74461 agataagtac tgtttactat gaagaagatg aaaagatagc agaagacata gttgaagatg
    74521 aatctaaatt aaatactgaa aaagagggag atttaaatta cttaagtaca tatttaagaa
    74581 gagatgatga agttgagaaa catatggata taattcacga aatggctgtt acaggaaaat
    74641 ctataataga acctatgaga actaaactac cagtaatttc ttgggatgat attttaatta
    74701 tgggtgctca attaaatcca ttacctttaa atgagcatga tgaagtaaat acaacaacaa
    74761 taataggaaa aaaagcaaag aaacctatga ttatagaaaa tccagtttat atttcccaca
    74821 tgtcatttgg agctttgtct aaagaactaa aaatagcttt agcaaagggt gcagcccaaa
    74881 ataagacagc tatgtgtagt ggtgaaggag gtatattacc agaagagaag gaagcttcat
    74941 acaagtatat ttttgagtat gtaccaaata aatatagtgt aactgaagaa aatcttaaaa
    75001 attctgatgc tatagagata aaaattggtc aaggaacaaa acctggtatg ggaggtcatc
    75061 ttcctggcga aaaagtaact gaagaaatag caaaagtaag aaataagcct gtaggtcaag
    75121 atgtaataag tccatcttgt tttgaggaaa tacaatccaa agaagattta aagaaacttg
    75181 tagatgaact tagagaagtt tcagaagggc gtccaatagg tgttaaaatt tcagcaggtc
    75241 atattgaaaa agatatggaa tttatagctt atgctaaacc tgattttgta actattgatg
    75301 gtcgtggtgg agctactgga gcaagtccaa agttgcttaa agatgcaact tcaattccaa
    75361 caatatttgc tctttatcgt gctagaaaat acatagatac acatggatta gatatagatt
    75421 tggttataac aggtgggctt cgtatatcta ctgattttgc taaggcaatt gctatgggtg
    75481 ctgatgcagt tgctattgca agttctgctc ttatggcagc ggcgtgtcaa caatatcgta
    75541 tatgtggttc tggtaagtgt cctgtaggag tagctactca ggatgaggaa ttgagaaaaa
    75601 gattacatat agaaaacagt gctaatagag tggcaaactt tttaaatgta agtttagaag
    75661 aacttaagac ttttgctaga atttctggtc ataaagatat acatgattta agtgttgatg
    75721 atttatatac tgttaactct gaaatatcaa attatacaaa catacagcat gtatagattg
    75781 aagtttgaaa ctattagatt ttagatagct ataaaagtaa atgataaata tattttataa
    75841 aagagagtgt cttaaaatga actttttagt tcataagtca ctcttttttt gatgaagcca
    75901 aatatattta tcattttagc aatgaaaaag aatcttatct ctttattttg agatagactc
    75961 cttctattta tgaaaattaa agatattaaa ttgtaaaata ttctgtgatg tcgtactatt
    76021 aaactaaaga ttctgtactt taaagtaaat aaaaatttaa ggagtgatta ttatggaaag
    76081 attgaagata caagttttag ttgacaataa tacttatatt gatagatact ttgttggaga
    76141 accagcagta agctattata ttgagattga tggaaatagg attttgtttg actcagggta
    76201 ttcagatgta ttcatatcaa acgctgaaaa attaaatata gatttaggaa atttaactca
    76261 tgttgttttt tctcatgggc ataatgacca tacaagaggt atccagtttc tagaaaatag
    76321 gtatgattta tctacagttg aacttatttc acatcctaac tgttttatac ctagaaaaca
    76381 tggagagaaa agcataggag ctccattttc tgctgaggaa attaaaaata tttttatgta
    76441 taatcctaag gataagccat ttaatctaag taagaattgt gtgtttttag gtgaaatacc
    76501 ttctataaat gattttgaaa aaagagctaa aattggtaaa tgtaaaatag gagatttgtg
    76561 ggaagatgat tatgttttag atgattctgc tatagtttgt aaaactgata aaggtatttt
    76621 tattgttaca ggatgttctc atagtggaat ttgtaatata gtagagtatg ctaaaaaggt
    76681 atgtggagat gatagagtta ttggtatact aggtggtttt catctttttg aattgaataa
    76741 taggttagat agtacaatac aatatttgga taaagaagaa atgagaatgt tgtacccttg
    76801 tcactgtgtt tcttttaagg taaaagcgaa gatgaatgaa atattgaata taaatgaagt
    76861 tggagtaggg ctgaccataa gtatatagta tttgaaagta tataagattt aagttgaagg
    76921 ttaaaaagat attttctata gaaaatatct tttttgttac gtttatttta agagaaatca
    76981 atatactttt atatgaaata ttgtaaaaaa atttattttt aatgagaata tattttcatt
    77041 aataaacaat tttattatgt attaataatg ttagaataaa tataaataaa tcaaagttac
    77101 ttacattaca gtatattttt tcacaaaata tattgattta ttcttttaaa gtttgataat
    77161 tccaatgaat gta
//
LOCUS       DAMJXI010000012        73317 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.012, whole genome shotgun sequence.
ACCESSION   DAMJXI010000012 DAMJXI010000000
VERSION     DAMJXI010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 73317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73317
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.012"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(279..920)
                     /locus_tag="PC465_001102"
     CDS             complement(279..920)
                     /locus_tag="PC465_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HDF2648427.1"
                     /translation="MNNNFQDNQTINLIQSRRSIRKFTTEQISDEQVNTLLHCAFAAP
                     SGCNKQPWHITVVQDQKLLKEISDDTLSRIHEVSNVEINKNFKLFYGAPTVLFISYDE
                     SSSWAPYDIGILTGNITTAAQALGLGSCIIGMVRGLFTPVEQGDIEGLVSVLDKEDVK
                     ESESIKMKFDTNKKYRELLDIPEGYSVPFGIAVGIPDGNLPNAREVVYKVSRV"
     gene            complement(1163..1966)
                     /locus_tag="PC465_001103"
     CDS             complement(1163..1966)
                     /locus_tag="PC465_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2648428.1"
                     /translation="MNKKGFTLIELLVVISIIGILVIVAVPALFRNIEKSKAVTCLSN
                     RENIKTQIVIAMAEESSKDKNEVIKEVLENKDGKYFETEPKCKSGGIYSATFDDGYDG
                     ITGIESIAKVYVTCTKHPDGVEMARDVHQSMKDLIASFAQDPSIIPGASKGNDDFRKY
                     LLDNKYKNGWPTIPDEFKAKYGLSKDTLYIQPYAYNPTKSDATVVVFANNKTGGNWYT
                     SLVYDYDEGRWYKGKNGISVAGRSWDVDTDSVKSVKTEIHSKEGWGPLN"
     gene            complement(2122..3297)
                     /gene="thiI"
                     /locus_tag="PC465_001104"
     CDS             complement(2122..3297)
                     /gene="thiI"
                     /locus_tag="PC465_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HDF2648429.1"
                     /translation="MVYNILIVKYGEIGVKGKNRYIFENRLIRNIRNMLKPIGRFNVY
                     KEYGRIYVDLEDYDYEEVIEEVRKVFGIVGVCPGVRAKKDYDTLKEIALKMLEEKIEA
                     GYKTFKVESRRGDKSFGLTSQEMSMDIGGYLLSKVGDRINVDVRNPEVKIKCEYREFH
                     TMVYSDTIPGYGGLPLGTNGRAMSLLSGGIDSPVATWMVAKRGMEVEAVHFHSYPFTS
                     ERSQEKVKDLAKILAKYCGRVRLHKVNILEIQKAIGENCNEEEATILSRRFMMRIAQR
                     LSEKRHCDALITGESIGQVASQTIQGLTCTNAVVDLPVFRPLIAMDKSDIVDIAKKIG
                     TFETSIVPEEDCCSVFSPRKPVTKPRLEKIEKSETALDIEKLVQDAIDKIEVEDIEF"
     gene            complement(3343..4494)
                     /locus_tag="PC465_001105"
     CDS             complement(3343..4494)
                     /locus_tag="PC465_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDF2648430.1"
                     /translation="MEIYLDNSATTKPYQEVIDKMVYALNTEYGNPSSVHRKGVEVEK
                     AIKEVRQDIAKSLGAKEKEIYFTSGGTECNNTIIRGITSLNKKRKNHIISTNIEHPSV
                     LNTLKDLEEDGFEVTYLEVGKDGKINIEDLKNAIKSTTCLVSMMHVNNEIGTIQPIGE
                     VGKYLKGLKEKIYFHVDAIQSYGKINFRPSKYNIDFMSVSAHKFHGPKGIGFMYIKEN
                     NRLKPMLTGGGQEIGIRSGTENVPGIYGLGEAVRILNKDLDAVISKVDNLKNILKNEI
                     IDNIEDIKINSPEDGVCHILNVSFRGTKGEVLLHYLEQKGIYVSTGSACSSKKKGSYV
                     LNAIGLTNEEINGTIRFSLSDMNTEEEMLEAVKVLKESICDLRSIMKRK"
     gene            complement(5142..5864)
                     /locus_tag="PC465_001106"
     CDS             complement(5142..5864)
                     /locus_tag="PC465_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004398740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDF2648431.1"
                     /translation="MITIKNLSKSFGDLNVLKNIDLEIAKGEIMVIVGPSGSGKSTLL
                     RCMNLLEIPTGGEIIFEGKNLVDKKTNIDEVRQNIGMVFQNFNLFPHKTILDNITLAP
                     IKLKKMTKEEAEKKAEILLSRVGLLDKKDSYPSQLSGGQKQRIAIARALAMEPDMMLF
                     DEPTSALDPEMVNEVLDVIKELAKEGMTMAIVTHEMGFAKEVADRVIFIDGGSILEDN
                     TPEEVFGNPKHERTKAFLAKVL"
     gene            complement(5923..6600)
                     /locus_tag="PC465_001107"
     CDS             complement(5923..6600)
                     /locus_tag="PC465_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF2648432.1"
                     /translation="MSLDFSFLSRFGTSFLEGTGVTVSISLVALCFGFIIGIIICMAK
                     ISKSKVLRAISSIYIEVLRGTPLLVQIYIVWFGLPQLGIRFPMLFGIPSEFIASAFAL
                     SVNSGAYVAEILRSGIQSVDNGQMEASRSLGLNYWSTMRYIIIPQAIKNILPSLANEF
                     ITLVKESSIISVIGVVEIMRTADIVKNAAFRALEPLIVAAAIYFVITFTLSRLVGLLE
                     KKLSVSN"
     gene            complement(6628..7443)
                     /locus_tag="PC465_001108"
     CDS             complement(6628..7443)
                     /locus_tag="PC465_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF2648433.1"
                     /translation="MKVFKKLLSLGLVLGLTLSLVGCSGGGEKTKLEQIKDNGKLVVG
                     TSAEFPPFEFHKVVDGKDSIKGFDIMLAEEFAKELGVKVEIKDMSFDGLIGALNADQV
                     DIVLAGMSPTPEREKSVDFSELYYLSRNAVIVKDADIDKVKTEDDLKKLRVGVQAGSI
                     QEEYVVNTLKMTTTKSLKAIPDLITELKNGNIDAVVTNEAVSLINVKKYDGIKMANTE
                     VGKDVTEGMAAAIKKSDNNKDFIELLNKKIKELQDGKKIEEFLNEASTEAASN"
     misc_binding    complement(7669..7879)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(8262..10328)
                     /locus_tag="PC465_001109"
     CDS             complement(8262..10328)
                     /locus_tag="PC465_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDF2648434.1"
                     /translation="MVELIITTNIDIRKLNENQLEAVEHIDGPCMILAGPGSGKTRVI
                     TYRIANMVVNKNIAPTRILAISFTKASSIEMKNRALNLSDDIRLNKVTYGTFHSVFFK
                     ILRYFERYNLDSIFDEKSKRMTIKAILKSLNIENADDDENIGQVINEISYVKNELMDK
                     NEFNSEVLTKDEFLKVYNLYEEQKSKVNKIDFDDMLIRTYYLLLNNKSALEMVRNVYK
                     YILIDEFQDINKVQFEVLKLICSPLNNIFAVGDEDQSIYGFRGARPDFLLEFEQYFNN
                     TKKIILDINYRSKSEIVHTANRLIDKNKNRYEKIIKCSQGDGGSVTYISPHDSEEEAL
                     YIAREIIDEIQKDYVEYSDFAVIYRTNIQSRALVDVFMDMRIPFVVKDSVITIYDHWA
                     SQDILAYLRIGINPKSNKDWLRIINKPFRYISKDSINMVKDENDFITALINKCNLHPK
                     QVKTINDLEIDLSYLNTLNPKNAISYIRTSLDYDRYVLDYCSNRKIKTNGLVEILNEL
                     ESSATNFNTVTEFLEHIDRVKTELTENNKNKQTEGVIFTTMHSAKGLEFRNVYIIGVN
                     EGTIPHEKSYDICKEEKKEEQLEEERRLMYVAITRAEEKLCISSTLNKYGKKVDKSLF
                     INDIKSPTKKEIDSIGVGDKVYHKKFHEGEIIKKDGIMFTIKFKDRERILDLKTCLLK
                     NIIYTI"
     gene            complement(10405..13434)
                     /locus_tag="PC465_001110"
     CDS             complement(10405..13434)
                     /locus_tag="PC465_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2648435.1"
                     /translation="MENNLRKNNSIMKKMIFPLIIVMLIQTSLFCATILWGGTIKKLN
                     DNSFDILNERVINRKNYIQNEMLQRWSNTSETEATINSSVKKVLNEKNSLIEDVGNNE
                     EINKDIIKSISNDLIYLLRKNSVTGAFIILSDKNINDKSIDSKGEISRTGLYIRDLDP
                     KFNPNDNSDLLIERGSSDIARSFGISMDSYWEPKFSFKSENEQDGDDFFYKPFRAAID
                     NPNVSSSNLGYWGSKFLLTNAGDRLMTYTVPLIYEDGTVYGVLGIDLSVNYLRELLPY
                     SEINGNKKGNYILGVDRNNDMAFENVISNGYSLKEKFWDGLHSNLEQKESYKNIYKIK
                     NKDNECGNGNIYASVQYLDLYNSNTPFENERWALLGIIEEKSLLSFSKRVEKLVIISI
                     AISLLIGLIGIYIASRLFTKPIVLLANKVRNSNPSKPVNLDKINISEIDELSSAIELL
                     SANVADSSSKLSQIIEMVDMPIGAFELYKNAENVFCTKEFFSVFTTEIKFEEYGYMEK
                     NKFLKKLRGLDKYLQESYETENTYIYKFESKDKKLKWIRMNIFEDELKVLGVVVDVTK
                     EFIEKRKIEYERDFDILTNLLNRRAFHSQIQEKFKNKDELKIAAFIMWDLDNLKYIND
                     TYGHDAGDEYIRCAADILKKFISWNGIVSRLSGDEFYVFIYGYESKDSIRDIINSVKK
                     QMNNTLLKLHDGTEFKIRASAGISWYPDDSTNYDELMRYADFAMYQIKNTIKGEVSEF
                     DINIYNKDSFLLSNREELNKLIDGQLVEYAFQPIVDCKGKVFAYEALMRPKIKTFSSP
                     IDVIRLARSQSKLYQIERITWFKALKSFKKYKEKFGDCKLFLNSIPNNNLSKVDFEEI
                     EDLYGEYLNRVVLEITENDKINEDFIEKKKAYIDHWNIEIALDDFGTGYNGDAVLLYI
                     MPDYVKIDMSIVRGIDKDENRQKILKNLISYSNERNIKVIAEGVETKGEMETLINLGV
                     DYMQGYYISKPSFIPEDISDKIKKELKICHENRNDVV"
     gene            complement(13487..14947)
                     /locus_tag="PC465_001111"
     CDS             complement(13487..14947)
                     /locus_tag="PC465_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDF2648436.1"
                     /translation="MNRCKFAKLIITSMIVLLLTGCSLKKEDNYKLDPENPTSIQIWH
                     YYNGQQKMAFDKLVKEFNDTVGAEKGIIVEAFSQGNVVDLSEKVLDSANKKVGSEDVP
                     NIFAAYSDTAYEMDKLGLLVDMDKYISKEELNEYIDEYVEEGRINSKDEFKLFPIAKS
                     TEILMLNKTDWDKFAKATNSNINDIKTIEGLVETSKKYYEWTDSLTKEPNDGKAFFGR
                     DALANYIIIGSKQLGVEIFSVKDGKVTLNIDEKVMKKLWDNFYVPYINGYFASYGKFR
                     SDDAKTGDILALVGSSSGAAYFPDRVMLNDNESYNIETSVFQAPRFKGEGKYAVQQGA
                     GMAVTKSTKEEEYASVEFLKWFTDKEPNIKFSIASGYLPVKKKTNDLDVIKEVMKKDN
                     LSLSDKVEGSIASSIEQINSCNLYTNKAFDGGTKARQILEYSMLDKAKEDSNKINELV
                     KSGTSKKDAVAQFNNDKNFKTWFENFKAELENAIKK"
     gene            complement(15039..15413)
                     /locus_tag="PC465_001112"
     CDS             complement(15039..15413)
                     /locus_tag="PC465_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648437.1"
                     /translation="MGNKNKNTKYKDKTRERYNKKVENLNKEKLNKINKQSKKVDKID
                     DIINKSSIVLCVLLVVFSLLYLFKLVQLNIIMILLVITVAIQQGLVSFGAFRNKNYVK
                     ALFSIFVIVCFLIAFKYVVNPV"
     gene            complement(15589..16329)
                     /locus_tag="PC465_001113"
     CDS             complement(15589..16329)
                     /locus_tag="PC465_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDF2648438.1"
                     /translation="MLYDEDEKEENNERWLLTYSDLITLLMIFFVIMYSMSNVDAEKY
                     KQLSQSLNSAFGGSSGVIEGGNSKIEPVVEPGSNDLDTLQNAKFKKFGEEIQKYLNEN
                     GMANSVSLRVQDRGLVISLKDTILFDTGKAIVKDNSRDKIIQIGKMLNEMNSYMRVEG
                     HTDNMSIKNSEFKSNWDLSVMRATNVVQLLIDNAGIAPDKLSAVGYGEFRPIAENSSE
                     EGRSKNRRVDIVLVDSKYDNVENVSKDK"
     gene            complement(16350..17138)
                     /locus_tag="PC465_001114"
     CDS             complement(16350..17138)
                     /locus_tag="PC465_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HDF2648439.1"
                     /translation="MTTLIFFIVGIASLVVAFVIDGGHVGALFVFSSALVVFGGTIGA
                     VGASTPFPVFKKSIKIMLLAFKNKKPNNIENIIYFKEIATKARKEGLLSIDKEISEND
                     ELDPFIRKGLELMVDGVDAVTIRNILESQIQITSKRHKEGIAIFDSAGGYAPTLGIIG
                     TVMGLVHILGNLSSNPDALGPQISVAFLATLYGVGSANLIWLPIASKLKAINQQEVSE
                     RLLVIEAILSILEGDNSNLMTEKLKIFLNSKELIELEEIGGRAE"
     gene            complement(17226..17316)
                     /locus_tag="PC465_001115"
     tRNA            complement(17226..17316)
                     /locus_tag="PC465_001115"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17280..17282),aa:Ser,seq:gct)
     gene            17524..18075
                     /locus_tag="PC465_001116"
                     /pseudo
     CDS             17524..18075
                     /locus_tag="PC465_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418382.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
     gene            complement(18901..19413)
                     /locus_tag="PC465_001117"
     CDS             complement(18901..19413)
                     /locus_tag="PC465_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648440.1"
                     /translation="MKVKKFKSGIVMALTVMAIGASLTNVSAMELNKSKEFETKYNEM
                     KRDFQEEYGKEDKFNITLDDEFTKEEVNGAKGIIKTTNKMNNEVVVLNYFDEMKSGIE
                     FELKPKAEKNAILRDEFQQGYGKEDKFKVVLDDEFTKEEVNGAKGIIKTTDKETGEVI
                     VYNYFDELEK"
     gene            19966..20850
                     /locus_tag="PC465_001118"
     CDS             19966..20850
                     /locus_tag="PC465_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HDF2648441.1"
                     /translation="MKKRLIIMILSVVLVLSSILTIFAYSNIKYNNNNKLIYSNMIDK
                     KTQNSVKEILKENKINEKDIDTFIKAVNNYNKLQVKILQNNINISKSGYSSINAKQVP
                     YNLEKLQDNWVKKFPDYMDVNCRITAFRLFKDFINSNKKFTGDSIDLNVDLDTIMNNK
                     DAKFSTKDVEKFINFFSAIPAKDTDDTIKISEQIKNEWKKRKISFKNNKNISIINGFL
                     RYPETKNVFIGHTGICIKTKNGILFLEKYGVTSPYQVTKFKNKEDVKNYMFNRLKMSE
                     GEIELPDPIIMENDKLMK"
     gene            complement(21163..21942)
                     /gene="hisJ"
                     /locus_tag="PC465_001119"
     CDS             complement(21163..21942)
                     /gene="hisJ"
                     /locus_tag="PC465_001119"
                     /EC_number="3.1.3.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ"
                     /protein_id="HDF2648442.1"
                     /translation="MKDGHIHSPYCPHGSKDDFEKYVQRAMDVGITEMTFTEHFPYAN
                     GFRDPAPENDSCMSIEDLPKYFNDVKKLKEKYEGKIKINVGSEVDFIEGYEEGIKENL
                     NKYGKELEDSLLSVHIIKIDDDYYCVDYSVEEFQNLIDKLGSIEAVYNKYYETLIKAV
                     NSDLGIHKPKRIGHLNLVRKFNQVFPYDYKGNTILEELIKLIKEKGYELDYNVSGNRK
                     EYCKEPYIDGYLLELVKKYDIPLVLGSDSHCAEEINKYDII"
     gene            complement(22512..22862)
                     /locus_tag="PC465_001120"
     CDS             complement(22512..22862)
                     /locus_tag="PC465_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter"
                     /protein_id="HDF2648443.1"
                     /translation="MIFDKEIVRYHHGHHDHDHCHEHTHGDICHEHPHDHAHDHDHEH
                     SHEESSESKDEKTLKILLVHWINHNETHEEGFREWVEKARAIGKEETAKSIEKAIEYM
                     EEANKMLLEAKKHM"
     gene            complement(22878..23294)
                     /locus_tag="PC465_001121"
     CDS             complement(22878..23294)
                     /locus_tag="PC465_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3842 family protein"
                     /protein_id="HDF2648444.1"
                     /translation="MIIAVIDGMGGGIGAQIVSSLREELPTYVEIYALGTNSIATSSM
                     MKAHANKGATGENAIVVSAKKANIIVAPISVIIPNSMMGEVTCNISEAIADSEALKIL
                     LPIMPENVELVGLEGKPLALLVKDSVNLIKKEFNIK"
     gene            complement(23313..23504)
                     /locus_tag="PC465_001122"
     CDS             complement(23313..23504)
                     /locus_tag="PC465_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CooT family nickel-binding protein"
                     /protein_id="HDF2648445.1"
                     /translation="MCESSAFICKSNNELEKVMENVVNIDPCDGKIYLTDLLGEQKII
                     DGIIKEIRLMDHKIIIQEN"
     gene            complement(23655..24470)
                     /locus_tag="PC465_001123"
     CDS             complement(23655..24470)
                     /locus_tag="PC465_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HDF2648446.1"
                     /translation="MNQWRVIHNKSYEGAMNMAIDEAIFTAYKKGHNKPTLRFYTWEP
                     ACLSIGYFQKLEDEIDLDKCRCMNIDYTRRITGGRAVLHDNELTYSIIIGEDNPLIDK
                     SINLSYRYISEGLVKGLNLSGIETDNLNRGERISRENLSAACFNAHASYEVTINNKKV
                     IGSAQSRKDGVLLQHGSIILDFDVEKLFKLIKTKTPELKERAMKFTAKKASGIENEIG
                     RKIDIDILQKNIVKGLAEQFNVEFVEGDLTDYEKQLVKELYEKYKNEEYNKKR"
     gene            complement(24517..25455)
                     /locus_tag="PC465_001124"
     CDS             complement(24517..25455)
                     /locus_tag="PC465_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2648447.1"
                     /translation="MIRLSVGTAIELGILNKKSDIPPTTAYIMIGEKCINKCSFCSQS
                     IESSTRKDKLSRVIWPEFSKEEILDALKAYKGKNIKRICIQSMASEEAHNSVLDFINY
                     ISGRIDMPISLSAKLENDEQIKKFFSVGVDKIGIAIDAANKELYEKIKGNNYDEKLKF
                     ITEMSKSYPNKISTHIIVGMGESHEDIYNLYTYLKENDVMISLFAFTPVRGTKMEKIS
                     QPSIESYRRVQLMSYMINKGYPKEYFKFKNGYLNSIKLDNDILKDINKGYPFEIRGCK
                     DCNRPYYNERPGSTIYNYSRPLNQSEIDLAIREINL"
     gene            complement(25452..26324)
                     /locus_tag="PC465_001125"
     CDS             complement(25452..26324)
                     /locus_tag="PC465_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2648448.1"
                     /translation="MNKNLSEKMKIAFDIKLKNFGNKIEFAYPNQTLALSTTSNQCSL
                     KCAHCNGHYLNNMVPIEEYEEKVQSRNITSFLLSGGCSYEGDVPINTHINTIKNLKEQ
                     GYRLNAHLGLMDKDSIVELCKYLDIVSFDLVFDDETIREVYKMKKSKEDYIEVYNTIQ
                     EHTEVAPHICIGLKGGQIKGEYEIIEYLQKNPPNKLTFIVLIPTKGTEYENVEPPELE
                     GVADILCEARINLPDTEINLGCMRPRGVYRKELDQLSIMCGVNRIVLPSRSAKNKAIE
                     MNMTINECKECCVL"
     gene            complement(26349..28277)
                     /locus_tag="PC465_001126"
     CDS             complement(26349..28277)
                     /locus_tag="PC465_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4445 domain-containing protein"
                     /protein_id="HDF2648449.1"
                     /translation="MIKVSFTPNNKEVYCNEGDILLEVARNADIFIDAPCNGNVSCGK
                     CKVKLLNGKVDTEKTRHITDDEWEQGYILACCTKVISDIEIEVPSKVSSSMHGMKIEG
                     SNKKEDREIFERAKKIIEEHNLQFKTNIKKKYIEMEEPNLDDNISDVDRLERYVRNNL
                     GYNEIDFRLDILRKMPTVFRKSDFKVTITYVQKQKKLTIINIEQGNKENSLYGVAIDI
                     GTTSVVVCLVDLYSKEVVDKASSGNAQIKYGADVINRIIYSTKKNGLETLHKAIVEET
                     INPLLKTIYERNGIDKEDVVTLVAAGNTTMTSLFLGVYTDFLRQEPYIPPFLKSPKLM
                     GENVGLFVNDSAYVYLAPSVASYVGGDITAGVLSAGIWSSEENVLFIDLGTNGEIVFG
                     NKDYMMSCACSAGPAFEGGGISCGMRASAGAIEKVIIDKDTLEPTLKIIDECAPVGIC
                     GSGIIDLICQMITKGVIDRRGKIYRDLDNKRVRFNEHEIGEYVLAFKEEFDLENDIVV
                     NEVDIDNFIRAKGAIYSGAYTLVDSLGMDFSILDRVYIAGGIGNNLDIENSIIIGLLP
                     DIDREKFTYIGNSSLVGSYLALISKDAKNKLEEIGNQITYVELSVYPSYMDEFISACF
                     LPHTNIEQFPTAKKLLEE"
     gene            complement(28389..28766)
                     /gene="gcvH"
                     /locus_tag="PC465_001127"
     CDS             complement(28389..28766)
                     /gene="gcvH"
                     /locus_tag="PC465_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HDF2648450.1"
                     /translation="MKLLPELKYSKDHEWVKVIDGDVVYIGITDYAQDQLGEILFVET
                     PEVEDTVTKGVDFGVVESSKVASDLISPVNGEVLEVNEKLEDEPECINEDPYENWILK
                     VKLADVAELDTLLSDKEYEAGLE"
     gene            complement(28853..30979)
                     /gene="cdhC"
                     /locus_tag="PC465_001128"
     CDS             complement(28853..30979)
                     /gene="cdhC"
                     /locus_tag="PC465_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CO dehydrogenase/CO-methylating acetyl-CoA
                     synthase complex subunit beta"
                     /protein_id="HDF2648451.1"
                     /translation="MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSL
                     PCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYST
                     MDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
                     LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLN
                     GLLEYTANRVPAFVNAFGPLSELVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYD
                     KIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKE
                     ATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNY
                     IEGVMHVGQRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDA
                     EKVSELKGEAIAKYNARDERLASLVDESVDTFYSCNLCQSFAPAHVCVVTPERLGLCG
                     AVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVESVTLYSI
                     LEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFM
                     GHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDET
                     IADDSEGVLAFLEEKGHPALAMESVM"
     gene            complement(31036..31842)
                     /locus_tag="PC465_001129"
     CDS             complement(31036..31842)
                     /locus_tag="PC465_001129"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HDF2648452.1"
                     /translation="MEKFMIIGERIHCISPSIRKALAERDPAPILKRAKEQLEAGAHY
                     IDFNIGPAERDGEEIMTWGIKLLQSEFNNVPIALDTANKKAIEAGLKVYDRTNAKPII
                     NSADAGSRFDLIDIAAEYEAMVIGLCAKEGIPRDNDERMAYCQEILEKGLMLGMEPTD
                     ILFDPLCLVIKGMQEKQVEVLEAIKMMTEMGLLTTGGLSNVSNGCPKHVRPVLDSAFL
                     AMAMANGFSSAIMNPCDPELMKTVKSCDIINGASLYADSFLELNEGGFAF"
     gene            complement(31892..33259)
                     /locus_tag="PC465_001130"
     CDS             complement(31892..33259)
                     /locus_tag="PC465_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit gamma"
                     /protein_id="HDF2648453.1"
                     /translation="MALKALDIFKLTPKKNCKDCGFPTCMAFSMKVASGAVEVGKCPH
                     MSDDAIAKLSEATAPLMKALKVGAGASEYELGGETVLFRHEKTLVSRNRYAVSFCTCM
                     SDEAVDAKIANMKKVDYVRIGEQMKVEMAVLEYCGDKDAYLKLIDKIKGSGLEVAYIL
                     ACDDAQVVKEAVEVLKDARPMVYGATKENYKDMIEVVKGASLPLGVKAGSLEELYETV
                     ELIQAAGYKELVLDVTGENIKDTYTNAIQVRRTALKEQDRTFGYPSIVFANRLSNSNP
                     MMEVALSSIFTIKYGSIIVIDDISYAKALPLFALRQNIYTDPQRPMRVEPKIYPINNP
                     DENSPVLVTVDFALTYFIVAGDIERSKVPVWLVIPDAGGYSVLTSWAAGKFGGNSISA
                     FIKESKVEEVTNCKDLIIPGKVAVLKGDIEDNLPGWNVVIGPEESMELPKFLKGYQEK
                     ACQTN"
     gene            complement(33290..34234)
                     /locus_tag="PC465_001131"
     CDS             complement(33290..34234)
                     /locus_tag="PC465_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit delta"
                     /protein_id="HDF2648454.1"
                     /translation="MAFKMSTQKYSGKISEVEVGIGEKAIKLGGENVLPFYSFDGEVG
                     NSPKIGIQISDVYPESWTDSYKELYKDVANCPVEWAKYVEANTQADFICLKFDGSDPN
                     GLDKSVDECADVAKAVIEAIKLPLVVAGSGNHEKDGKLFEKLAQTLDGHNCLFMSAVE
                     DNYKGVGASAGMAYAHKVGAESSVDINLAKQLNVLLTQLGVKGENIVMNVGCSAVGYG
                     YEYVASTMDRIRLAAFGQNDKTLQMPIITPVAFEVGHVKEAIAPIEDEPDWGCPEERT
                     IAMEVSTAASVLVGGSNAVILRHPKSIETIKELVNALA"
     gene            complement(34254..35024)
                     /locus_tag="PC465_001132"
     CDS             complement(34254..35024)
                     /locus_tag="PC465_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2648455.1"
                     /translation="MGYNIAVAGKGGTGKTSLTGLLIDYLVKDKKGPVLVVDADANAN
                     INEVLGIEVEATIGEIREEVNQREKLGNAFPGGMTKAQYLQFRLNSIIEEGEGYDLLV
                     MGRSEGEGCYCFVNGILREQVNKISGHYKYLVMDNEAGMEHLSRKVTRHVDTLLLVSD
                     CSRRSIQAVARIRDLAEELKLSVGRILLIVNKVPNGVMNDGVKEEIEKHNLELIGVVP
                     MDELIYEYDSTGIPLVNLPEDSKSKVAMKEIFAKLELK"
     gene            complement(35080..36465)
                     /gene="lpdA"
                     /locus_tag="PC465_001133"
     CDS             complement(35080..36465)
                     /gene="lpdA"
                     /locus_tag="PC465_001133"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDF2648456.1"
                     /translation="MKIVVVGGGPGGYVAAIKASMLGADVTVVEKRRVGGTCLNAGCI
                     PTKALLASSGVLNTVKEAKDFGIEIDGTVKPNFTAIMERKNKVVNQLISGIEFLFEKR
                     GVNLVNGFGKLIDKNTIEVTKDDGTVETIKADKIILANGSVPVVPRMFPYDGKVVITS
                     DEVLGLEEIPESMLIVGGGVIGCEIGQFFRALGTEVTIVEMVDQILLNEDKDVAKQLL
                     RQFKKDKIKVITGIGVQTCEVVDGKAVATLSNGKVIEAQYALVCVGRRPNLDNSGVED
                     IGIEMERGKVVVNEHLETNVEGIYAIGDIIDTPFLAHVASKEGIVAVENALGKTKVVD
                     YRAIPRCVYTEPEVAGVGKTEKQLEAEGVEYNVGQFDFRGLGKAQAIGHFQGFVKVIA
                     DKETDKIIGAAVVGPHATDLLTELSLAVHLGLTVEQVGDAIHPHPSLSEGLMEALHDV
                     HGECVHSVPKL"
     gene            complement(36509..37390)
                     /locus_tag="PC465_001134"
     CDS             complement(36509..37390)
                     /locus_tag="PC465_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HDF2648457.1"
                     /translation="MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAA
                     NVTDFQSAVMRATSLATCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLL
                     ALTGDHTSVGDHPQAKGVFDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTP
                     EYSPIEVQLLKMKKKIKAGAKFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSP
                     GMAKFMTANVPGIFVPDEQIERLRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIM
                     AIGAEENIPAILDAAGL"
     gene            complement(37426..38100)
                     /locus_tag="PC465_001135"
     CDS             complement(37426..38100)
                     /locus_tag="PC465_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase C-terminal
                     domain-containing protein"
                     /protein_id="HDF2648458.1"
                     /translation="MIISENKPLEEVLGYLKDFDKLVLVGCNQCAATCKSGGEEEVLK
                     MKETLEGEGKKILGYVMLDPACNLLKSKKDLKALKEETKEADAVLSLACGDGTQTIVK
                     NLKDKPVYPANNTLFIGEVQRVGEYEEACKACGDCELGWTGGICPVTMCAKGLMNGAC
                     GGAKNGKCEVNSENDCAWIKIYERLEAIGQLDNLAEIRPPKDYSKQNNPRSISAKKKK
                     EAAANS"
     gene            complement(38137..39009)
                     /locus_tag="PC465_001136"
     CDS             complement(38137..39009)
                     /locus_tag="PC465_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylene-tetrahydrofolate
                     dehydrogenase/5,10-methylene-tetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HDF2648459.1"
                     /translation="MEGMSTKGQIIKGKPVADKISEELIKEVDLLVKEGINPKLTIVR
                     VGARSDDLSYERGALKRCQNIGITTEVLELAEDITQEEYIDVLKRVNDDKNVNGILCF
                     RPLPKHLNEEVIKYVIAPEKDVDCFSPINSAKVMEGDKSGFPPCTPTAVVEILKHYNV
                     DLKGSKVTVLGRSMVVGKPVSMLLLSEHATVTICHSKTKNLSGVAAEADVLIAAIGRA
                     KMVDESFVKDGAVVIDVGINVDEEGNLCGDVDTNAVLDKVSMITPVPAGVGSVTTSIL
                     AKHVVKACKLQNNK"
     gene            complement(39101..39733)
                     /locus_tag="PC465_001137"
     CDS             complement(39101..39733)
                     /locus_tag="PC465_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HDF2648460.1"
                     /translation="MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCN
                     LTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKR
                     IKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
                     GGQLNVVININSIQDKEYVNKVKTEVDKLVEDGVKICDEVYAKVEKALGK"
     gene            complement(39838..41514)
                     /locus_tag="PC465_001138"
     CDS             complement(39838..41514)
                     /locus_tag="PC465_001138"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014355320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HDF2648461.1"
                     /translation="MGFKSDIEIAQEAKPQDIREVAKKLGLGEDDVELYGKYKAKVDY
                     NLLKRETGKKAKLILTTAINPTPAGEGKTTTTIGVADAFAKLDKNVLVALREPSLGPV
                     FGVKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMLDNHIHQGNALRIDPK
                     KITWRRCVDMNDRQLRNIVDGMGKKGDGAVRQDGFDITVASEIMAAFCLASDISDLKE
                     RLGNIIVGYSYEGEPVTARQLKANGAMAALLKDALKPNLVQTLEGTPSFVHGGPFANI
                     AHGCNSVIATRMAMHFADYVITEAGFGADLGAEKFLDIKCRMANLKPDAVIIVATVRA
                     LKYNGGVAKADLNNENLEALEKGLPNLLKHVENITQVYGLPAVVAINRFPLDTEAELK
                     LVEDKCKELGVNVALSEVWAKGGEGGIAVAKEVLRLLDEEENNFRFCYEDDLSIKDKI
                     NAIATKIYGADGVDYTPEADKEIANLEKLGFTKVPVCMAKTQYSLTDDQTKLGRPTGF
                     RITVRQATISAGAGFIVALTGEIMKMPGLPKVPAAEKIDVDENGVIAGLF"
     gene            complement(41763..42542)
                     /locus_tag="PC465_001139"
     CDS             complement(41763..42542)
                     /locus_tag="PC465_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2648462.1"
                     /translation="MKIAITGKGGVGKTTFSSMLSRMFAEDGYRVVAVDADPDANLAL
                     ALGFPKEVYESIVPISEMKKLVSDRTAASVGSFGKMFKMNPKVDDIPENFCKEYNGVR
                     LLTLGTVDSGGTGCVCPEHVLLKRLCSHLILQNKDVVVMDMEAGIEHLGRGTAQGVDA
                     FIVVVEPGERSLQTYRKVKKLGHDIGVNKVFVVGNKIRNKEDEEFIIQNLEDGESLGF
                     IYYNQDVIDSDRANQSPYDSSETTKEQIKAIKDKLMSLKDK"
     gene            complement(42852..44771)
                     /gene="cooS"
                     /locus_tag="PC465_001140"
     CDS             complement(42852..44771)
                     /gene="cooS"
                     /locus_tag="PC465_001140"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HDF2648463.1"
                     /translation="MDEKMLTIDLNSQKMIAKAREEGVETMYDRKEGFKAQCGFGLQG
                     VCCRICGMGPCRISPKTPRGLCGADEHTIVGRNFARMVAGGTAAHSDHARDIAHTLAL
                     ADPNGNYKIRDEAKLITLAKEWDVETEGRDIYDVAHEVAEIALMEFGKPFGTLRFIKN
                     APEPRQKIWKEYAIEPRAIDREIATIMHSTHIGCTGDIDSLIHMSLRTSMADGWGGSM
                     IGTRLSDILFGTPVPRRTEANLAVLEENKVNIILHGHEPALSEMIVLASEEPDLVALA
                     KEVGADGINLAGMCCTGNEITMRHGVKIAGDFHQQELAIITGAVEAVIVDVQCIFPAL
                     ARVADCYHTKFVTTSPKAKITGSTYIEFREEQALDDAKAIVKEAILNFKNRDKSKVLI
                     PELKSGATVGYSVEAVVNQLDRVVNSHIDPAGTVKPLTDCLKAGVLRGAAGVVGCNNA
                     KGVSNEAHVTIMKELIKNDIIVVTTGCGASAAAKFGLMESDAAEKYAGKGLATVCKLV
                     GIPPVLHMGSCVDISRILDLVGAAANYLDMDMCDLPVVGIAPEWMSEKAVAIGCYVVA
                     SGIDTYLGIMPPIAGSSRAVDILTSELKDKVGATFTVNTNPKELAATIIEDIEKKRVH
                     FEALVEEKMAEKAEA"
     gene            complement(45378..46289)
                     /locus_tag="PC465_001141"
     CDS             complement(45378..46289)
                     /locus_tag="PC465_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HDF2648464.1"
                     /translation="MIKKLDDILEQLKGGEKIVLSVAAAHDKEVLMAIKDAVERNIIT
                     PILVGNEGKIREISKEIGFDLSGIKIVDKDDIKECAEIAVKLVSSKEADFVMKGLLDT
                     SVILKEVLNKDYGLRTDSLLSHVMVYELEKYHKLLITTDGGMNIAPDYEQKAKILKNS
                     IKAAKALGMETVKVACLAAKEKVNPKMQATVDADMLAKACKEGEFGENVIVEGPLAFD
                     LAVSKEASEIKGFKSEVSGDVDIILVPTIEVGNGIGKAFTYMADSKSAGIIMGAKAPI
                     VLVSRADSHESKLYSIAYGAIVAKNMK"
     gene            complement(46405..46983)
                     /locus_tag="PC465_001142"
     CDS             complement(46405..46983)
                     /locus_tag="PC465_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDF2648465.1"
                     /translation="MNINEFLTHINQRKPVSSKSEIHEFMVKLSNEAMKITSKLNSSY
                     HEPEEVRSLFSELIGKKVDESFFMFPPFYTDCGKNITIGKNVFINSSCHFQDQGGIEI
                     GDNTQIGHNVVLATLNHGIAPEKRGTTYPSPITIGKNVWIGANVTVVPGVTIGDNAII
                     AAGAVVTKNVAENTIVGGVPAKLLRVIDEIPE"
     gene            47209..48132
                     /locus_tag="PC465_001143"
     CDS             47209..48132
                     /locus_tag="PC465_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2648466.1"
                     /translation="MEIRVLRYFLAIAREESISGAATFLHITQPTLSRQIMELEEELG
                     VKLLVRGNRKITLTNEGRLLHKRAEEIISLVDKVELEFDNPNEIISGDIYIGSGETEA
                     MRLIARTAHHFHQKYPNVRYHLFSGNADDVTEKLDKGLLDFGILIEPANIQKYDYAQI
                     PATDVWGLLMRKDSALASQSTINPKDLCNIPLIISRQTLVDKAISKWLQGSNEKLNII
                     ATYNLVYNASLLVEEGLGYALCLDRLVNTTENSNLCFRPLSPPLEAKLNIIWKKHQIF
                     SKAAEKFLLQIQKDFSSIMLDTSKLDTPKEK"
     gene            complement(48304..49446)
                     /locus_tag="PC465_001144"
     CDS             complement(48304..49446)
                     /locus_tag="PC465_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2648467.1"
                     /translation="MDFKIEKYLLKKAEELAFITIKHGGEFKLKSYEVPKGGLDVPIK
                     NEVLVKGIKEKTAQDKLNSMSIADAMIYIIGIDSKFKNNAEYEKFLNALSKDIDLDLK
                     SYMGYMSRKYFEIGEHTDSLIYIKAFITMYPDDLDAMYNYAIVCQEIAKQYQKDMDDK
                     AMNAFLLEAMAKLEKVIDVDENFALGYYHLGYHYYNQGQYLKTKLTWEEALRLGLDAD
                     LVAEVQENLGKMDFKVQYEEGYTLVFQGKFKEGLEKLLPLEEEHMDWWNLLFMIALGY
                     KGMDEIEQAKMYLEKILIIKPNQVDTIVELGLCEAYKNNLDKAIEYFEQAAKIKEDPE
                     ILCNLGMAYLNNGDIDDATYYIERAYELNPQDEITIACLRELGINK"
     gene            complement(49464..51218)
                     /locus_tag="PC465_001145"
     CDS             complement(49464..51218)
                     /locus_tag="PC465_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HDF2648468.1"
                     /translation="MKILLTTLNSKFIHTNLAIRYLKEFVRDLIEVNMKEYTINNDLD
                     YILKDIYKNEYDIILFSTYIWNVGDIVKLCDNLKKIRPNTKIALGGPEVSYDSYEAMK
                     KYDFVDYILYGEGELIFRDLVLHLQGKMEINDVNGLVYRQGNEIIVNKPMELLQDLDE
                     IPSPYENLNPKEYENRIVYYESSRGCPFNCQYCLSSTIPGLRYFSLDRIKSDLKALID
                     ARVSQIKFIDRTFNANRKVAMEIMDFLMKNDNGYTTYHFEVTAYLIDDKMLEFLADCK
                     EGLFQFEIGVQSTNEKTLDAVGRRDDFKKLSHVVQTVASYRNIHQHLDLIAGLPYEDY
                     KSFENSFNDVFNLGIEHLQLGFLKMIKGTGMRKVADEHGFKYKDYAPYEFLYNNYISY
                     EETLKLKDIEDILERYYNSKNFVLSMRYIIGRFYKQSPFKFFEVFAKYFDENGYFDLA
                     QGKNQLYKILMDFYNEKINIDNDVFNDILKYDYISLGKTSNIPQFFNKLDVDDFKNRC
                     HVFLQDNDNLSTYLPSFVDKPAKHIIKYVHFEPFRFNVVDLKNDINTEIREVENVVLF
                     EYDDKKIFEKSKTHKVEI"
     gene            51354..51560
                     /locus_tag="PC465_001146"
     CDS             51354..51560
                     /locus_tag="PC465_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648469.1"
                     /translation="MELIEKVSINSLSKRDLLLIIKSLEYTNENTQISDFIDLRNNIV
                     KELCFLTDTKEKDFLDYLEKNSTL"
     gene            complement(51565..52488)
                     /locus_tag="PC465_001147"
     CDS             complement(51565..52488)
                     /locus_tag="PC465_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648470.1"
                     /translation="MNDELLKKVYTSSFSSASRALKDLTIINTKSLIDDKTQRCVYID
                     ENRLRDELIYYRFYGEKIGNINFLNILLPLILSNTNIQKSEDEVIKLIKKYVIYFKKE
                     ELLFDYLLGSVVYNSIMHNLINNSKIEYVELLQSIKDKIIGFSIELDKSDVVKFQMAR
                     IKAIQLIDKYIDLKSEDYDEESILLNVLNVLYDVYMEDRTVENEGINSIKKSILSILG
                     EDSKLNEDNIDFIFSMSEYVVKLRKYKIGVKAYNKSIDPRSLIRLEEGNTIVDPIFNQ
                     ITVMSKTFNDNILSIKINSKSGIYILKFKKV"
     gene            complement(52742..54442)
                     /locus_tag="PC465_001148"
     CDS             complement(52742..54442)
                     /locus_tag="PC465_001148"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HDF2648471.1"
                     /translation="MQDFKVAISNCLKEKIEDLSKEEIEALIEVPPNKDMGDYAFPCF
                     KLAKVFRKAPNMIASELAESIEPSGEITKVIQLGGYVNFFVNKSQLAETVIKKVLDEK
                     ENYGHSDFGKDKTVIVEYSSPNIAKPFHIGHIRTTVIGNALYKIYDSQGYKTIRINHL
                     GDYGTQFGKLIVAFKKWGEKEVVESNPIPELLKLYVRFHDEAEQHPEMEDEARAWFNK
                     LENGDEEAQELWQWFRNESLKEFNRVYKLLDIEFDSLAGESFYSDKMNRVIELLEEKN
                     LLKESKGARIVDLEEYKMPPALITKNDGSTLYMTRDLAAAIYRKETYDFDKCIYVVGS
                     QQNLHFQQWFKVIELMGYDWAKDLIHVGFGMVALEEGTMSTRKGRVVFLEDALNQAID
                     KTKEIILAKNPNAKNVDEISKQVGVGAVVFQELSNSRIKDYTFSWERTLSFDGETGPY
                     VQYTHARCCAVLRKAEVEVTSDIDYSLLADEDSAEVLRVIESFNKNILLALKKNEPHI
                     VTRFMLDLAQAFNKFYHDNPILVENLEIRKARLALVLATKQTLENSLKLLGMHAPERM
                     "
     gene            complement(54854..55267)
                     /locus_tag="PC465_001149"
     CDS             complement(54854..55267)
                     /locus_tag="PC465_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HDF2648472.1"
                     /translation="MILVSACLIGINCKYSGDNNDNEKVKEYLKGKEFTLVCPEQLGG
                     LSTPRPPAEIVDGKVITKDNKDVTENFVRGANETLKIANLYVCSEAILKEGSPSCGCN
                     LIYDGSFSGKKIPGKGITARLLEEEGIKVKSEKDL"
     gene            complement(55333..57711)
                     /locus_tag="PC465_001150"
     CDS             complement(55333..57711)
                     /locus_tag="PC465_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HDF2648473.1"
                     /translation="MNEKSLRVLEYNKIIDLLKKKASSSLGLKYIENLVPNTDFVEVK
                     SMLEETSEAQSIIIKRGSVGLEGIHDIEDKVKRAYIGASLDPGSLIMIADTLRVARRL
                     RNSLSSSDEEDFNYPIIQSLSNSLYVYKDIEDQIYNAIISEVEISDNASSTLRDIRRR
                     IAQKNQSIRSKLNSIISSTTYQKYLQDAIISLRGDRFVVPVKSEYRSQVAGIVHDQSS
                     SGATLFIEPMTIVEMNNELRQLKLGEQEEIERILSELSAMVGEVSEDLISNQEILGRL
                     DFAFSKGKLSIQMRGIEPTLNEDKYLNIKNGRHPLLDKKKVVANTIYLGRDFHTLVIT
                     GPNTGGKTVTIKTVGLFALMTQSGLHIPADYGSSMCVYDNVFADIGDEQSIEQSLSTF
                     SSHMTNIVSILQNVTADSLVIFDELGAGTDPVEGAALAIAVLEDINSVGAKCIATTHY
                     SELKNYALTKPGVENAAVEFDIETLSPTYKLLIGVPGKSNAFEISRKLGLSDYVISRA
                     KEYINTENIALEDVLQNVEKNRIKAVEDREEAERLKEEIEKLKVEYDEKLEKLVSQRD
                     KMIEKAKSEAFSIIRQAKEEVDIIIKELRSLEQERASKEKNRKIEELRKELTSSMGSL
                     QPTVKSMIVPKVSNKEIKDLKPGEEVKVITLNQNGSVVSVDKKRKEAVVQIGIMKMTL
                     PFKSLQKTRKDVSTNVTKSTRNIIRSKSGSVKNEVDLRGLNLEEAIMEVEKYLDDAYV
                     AGLESVTVIHGIGTGVLKAGLQDILRRNRHVKSQRGGQYGEGGAGVTIVKLK"
     gene            58030..59481
                     /locus_tag="PC465_001151"
     CDS             58030..59481
                     /locus_tag="PC465_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HDF2648474.1"
                     /translation="MGNVLEGLKPESVFKNFEKISQIPRGSGNEKGISDFLLSFGKNL
                     GLETIQDESLNIIIRKPATKGYENCPGVVLQGHMDMVCEKEKNVEHDFLKDPIKLRID
                     GDMIYATGTTLGADNGIAVAMGMAILEDNTLEHPALEVLVTVNEEDGMNGADALDPSL
                     IKGQYILNMDSEEEGYLLVSCAGGKTCVVSLPVEYKKVEGDKQGLLVEVTGLLGGHSG
                     MEIVLQRANANKAIARVLSVLNVDYELASVDGGTKHNAIPREAKCVIAVNKADVESAK
                     KQINDILTAFKHEFTTSDPGMTYSVAETSVDKVLTKDCKEKVVQMSCLTPHGVQSVSL
                     DIEGLVESSTNFAIIETKESTIEFLTSVRSSVMSIRDEIADRIRLLAQALGANYDLIA
                     QYPAWEFKKGSKLEKICSETYEKLTGKVPTVMALHAGLECGLLLDKLPHAEAISIGPD
                     MFDVHTPNEHVSIPSVANVWDYVIEILKSMNQY"
     gene            complement(59685..62198)
                     /locus_tag="PC465_001152"
     CDS             complement(59685..62198)
                     /locus_tag="PC465_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF2648475.1"
                     /translation="MEDCVVNLKKLLLLIIVITSIFTSCIFSFGINAIGNDNRTIRVA
                     YPIQKGLTEIDEQGNYFGYTYEYLLEIAQYTGWNYEFVQVPGDINESITKLMKMLENG
                     EIDIMGGMLYNEPMQKIYNYAGNNYGVANTVLQALYENTDIDNIMSSQDVKKIRIAVI
                     ENSDTRLKELDEYCKMNLMSPELVYCKTNDEQLEALKSGKADVLLNVSMNPLEGVRTV
                     AKFSSKPFCFITPKGSTNLTQKLNSAINNIEQKDPYFSTTLYEKYFTPENNQMFLSDE
                     ETDYIKETEKLKVGVLLNKPPFQNIDKDTGELRGISIDLLNHICDKTGLEFELVPVKS
                     QEDLENMTKKREIDIVAGMIYDYEYSREHNIVMSRPFLSTQYTMMINNKLNENSLDGK
                     RVALAKGINYYGQFEENIVWYDNLEECIEAVNKGYADYTYGEGYSMQYYMNQPKYKNV
                     RLVPQTYKAKSICFGIIKKDKQELLNIFNKAIISISSEKMQSIVYQNTTYRQDFSLLY
                     IMQQNPIETIFIVASLLICIIGFMAFGLHTRTSMNEKISLELKKHTQLYEMTSEYFFE
                     YDYKQDKLIISMPEKGIETYYGLDKNDKESENGNIENERDKIRKEYNKKFFDVIKSQE
                     NGTTEMYSIMLDDTFHWIRVTSKIIYNDRKIPMYVIGKICNIDSEKEEKNRLLDKAQR
                     DSLTNIYNAAYIRKLTAQNLLNLSTEKNGALLIIDIDYFKSINDTYGHLLGDKVLIDV
                     AKVLDESFAKNDIVGRLGGDEFSVYINDIINKEELINKCNDVYNHIHLIKLPNGESLS
                     ISMGVVIAKPGQEYDELYQIADNALYDSKRQGRNRFKIV"
     gene            complement(62421..63242)
                     /locus_tag="PC465_001153"
     CDS             complement(62421..63242)
                     /locus_tag="PC465_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2648476.1"
                     /translation="MIDINLEKCVGCGMCESDCLVNAIKVKDDKAKVKNILCINCGHC
                     MAICPTDAIEMQGFDKNEVIEYNRESFELEPEKLLNFIKFRRSIRQYKDIEVEEEKIK
                     NIVEAGRYTPTGGNRQPIRYILVKEKLKEVKELAIQGLYNLALDTDDNDPVRSIYKNT
                     FKKMYKRYKENGNDSLFYDAPLLMVVVGDMSLGGSAYVDGGLAASNMELMAYSQGLGI
                     CYNGFFVMASNVEPKIKELLGMSENEAVITSFILGYPDVKYKRTVNRNTAKFEVR"
     gene            complement(63760..64236)
                     /locus_tag="PC465_001154"
     CDS             complement(63760..64236)
                     /locus_tag="PC465_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HDF2648477.1"
                     /translation="MKLTTICYIEKDDKTLMLYRNKKKDDIHEGKYVGVGGKFEQGET
                     PEECVIREVKEETGLTLKSLSYKGLITFPKFKDEEDWYMFLYFSDEFEGELSEKDLND
                     CKEGNLIWVDNDKIFDLNMWEGDRLFLNWAKTGNIFSAKIVYDNGKLKDYNVSFLD"
     gene            complement(64270..64848)
                     /locus_tag="PC465_001155"
     CDS             complement(64270..64848)
                     /locus_tag="PC465_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDF2648478.1"
                     /translation="MREEALEILFKYLETDRMRKHCYAVEAVMRELAKRLEPEKEEEW
                     AVAGLLHDLDSDIVGRKPGEICEGHATTTVELLKKENFGDEEMYRAILGHHDGMGVTR
                     TSLMEKAIYAADPITGFITAIALVYPDKKLTSVKTKSVIKRMKETRFASNVNRDAMRS
                     IEDIGIPFDEFAELSLNAMKNISDVLESAENN"
     gene            complement(64952..67552)
                     /locus_tag="PC465_001156"
     CDS             complement(64952..67552)
                     /locus_tag="PC465_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDF2648479.1"
                     /translation="MKKIELLAPVGSFDSLKAAVQNGANAVYLGGKDFSARASANNFD
                     RNELIEAVKYSHIRGVQVFVTVNTLIKQYEIEDFVEYVKFLYDIDIDALIVQDIGMAR
                     LIKKLLPDFELHASTQMVAHSLEDVKYLQSVGFDRVVLARELNVDEIKWICENTTVDI
                     EVFVHGALCVCYSGQCLMSSMIGNRSGNRGRCAQPCRQKYELIDINTGEVVKSNGDYL
                     LSPRDLSTIEDLDKIIEAGVLSLKIEGRMKKPEYVATVVSGYREAINEFVDKKKISIS
                     EEIINNLYTIFNRKFTKGYILGEVGKDIMNSNRPNNQGLYIGKVLDYNRKNKRLRVML
                     ENTLKKGDGINLGGGTIGRIIKDGEITTIAHKGDLIELDFVGEAKRNQLIYKTSDSEL
                     MDRVQATFQQDKEFIKTNIRAKVSIKLGKKPELFISDFCGNKSVVEGDKIVEKAIKVA
                     LSKEKIETQIQKLGNTPYKLKEIEIDLDEGVSMPISVLNQMRRDCIELLDEERIKIKD
                     RKFKKNRLKYQPNRVNKQKKLDTVPKIRVKVKNLEQLEAVLNYNVDLIYYEDINTLSK
                     ALQMVSSISIDSNISIDSSISMDLDTSSSLDTPKELMGSNTNNIDTLSNTSKIDTLNK
                     NHYNTAVTNKKLIYSAPRIVRNKEYKQFEILDNIKGINKVQIGNWGSMEYFKKKDLNI
                     DCYLNAFNSESINHFKEEGASTVCLSQELNLNEIKQTLKYTDVEIEAVIYGYAPMMVT
                     EYCPMGVVVRDCKKDKRVAKCKESSYALRDFTDASYRITQDIFCRSTIYNSKVTCMLD
                     NLYELEEIGIDVFRIDFTVEDSEMVKKVIEAHIEVLSNNYKLGKKATDLYKKLDEIGT
                     VAGHYYKGVE"
     gene            complement(68005..68688)
                     /locus_tag="PC465_001157"
     CDS             complement(68005..68688)
                     /locus_tag="PC465_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HDF2648480.1"
                     /translation="MTSKSQMSESFFLCSLLAITGGFLDIYTYVVRGKVFANAQTGNI
                     VLFGLNIAEGNVKESFYYLIPILAFMLGVFIAEKIRKYFTNNKTKIHWRQVIIIIEMI
                     TILIVSFIPRGRFNMFVNVAISFICSMQVESFRKVNGNSFATTMCTGNLRSATETLFH
                     YIHTKNIFMIKKSLQYYAIIIFFISGAILGTFFTKIFVEKSILICFFILAVVFGIMFI
                     NKDDSFNEN"
     gene            complement(68908..69498)
                     /gene="zapA"
                     /locus_tag="PC465_001158"
     CDS             complement(68908..69498)
                     /gene="zapA"
                     /locus_tag="PC465_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HDF2648481.1"
                     /translation="MNKVMVKIHGAEYPMVGDKSEKFMISIADFVDKEMDKITRQNPK
                     LSLSVAAILTALNISDLLFECSDENEKLIKANEELSKKVGASNEELQLEIKSLKLTIA
                     EKEAENREAETKMKELIEIIENKKQEIFELSNTTEGSRAELDAYKNKIEELSTQLEEA
                     NERATIAENLASEFQNKAYDLQLKCTGLNNDAKNVE"
     gene            complement(69523..71916)
                     /locus_tag="PC465_001159"
     CDS             complement(69523..71916)
                     /locus_tag="PC465_001159"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HDF2648482.1"
                     /translation="MLVSLKWLRDYVDIDMDVKEFADKMTMTGTKVETIDYYGEEIEN
                     ILVGKILEIKQHPNADKLVVTKVDIGDKVVQIVTGATNISEGDYIPVAVNGSKLPGGV
                     EIKQTDFRGELSDGMMCSAAELGIDEHYIEEYKRGGIYILDHEDSYELGKDIKDVLGL
                     KDALIDFELTSNRPDCKCMMGIAREAAATIGTKVKYPEIEVKESDEEIDFKVEIDNPD
                     LCRRYVARMVTDVKIEPSPYWMQRRLTEAGVRPISNIVDITNFVMLELGQPLHAFDIN
                     QVETGRIVVRNAKDGEKLVTLDDVERTLDKDMLVITNGEKSLGLAGVMGGANSEITSN
                     TKTVLFESANFKPENIRMTAKKVGIRSEASSRNEKDLDPNLAEIAANRAAQLVEMLGA
                     GKVLKGVVDVYPNKPEPKKLVVNPQRINHLLGVDVPMEQFVGILESLEFKCNLVANDK
                     LEIDVPSFRTDMEQEADVWEEIARIYGFENIPSVQLEGNTTAGIKTSKQKFMDALKDN
                     STAVGLNEILTYSFVSPKGVDKIRVPEGNAKRNFVKLLNPLGEETSVMRTTLIPNMLD
                     VLSTNVSHKIEEVSAFECGHIFIPQDSELPKEENRMCVGMYGKDVDFFALKGTIETIL
                     VNVGFKGYEIEPQDNNTTFHPGRCAKIVYNNKYVGTLGELHPDVIENYNLGQRVYVAE
                     IDIDFVFDNSDRTKNYVPLPKYPSTSRDIALIVKDDVFVKQIEDIIKENGQGLVESYK
                     LFDVYKGSQIEAGYKSIAYSITYRSKDKTLTDEDVAKVHDKILSELSEKLNANLRSN"
     gene            complement(71933..72952)
                     /gene="pheS"
                     /locus_tag="PC465_001160"
     CDS             complement(71933..72952)
                     /gene="pheS"
                     /locus_tag="PC465_001160"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HDF2648483.1"
                     /translation="MQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILK
                     EMGKLSAEERPVVGKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVL
                     KVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFY
                     INDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGK
                     DVTMAEFKGTMDIFVEKLFGSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKY
                     EGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMR
                     FLNQF"
     misc_binding    complement(73002..73236)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT        22682 a        13803 c         7901 g        28931 t
ORIGIN      
        1 ttaaattttt aacttggata aattttaaag catatactta aaattaacat acttgttttc
       61 tattttatta cacttaatcc ttatttttat cattctacaa aacaaaaata aaaaagaata
      121 agataataaa taaaatactt atcaccttat tctttattta attattttac aacgaaaaat
      181 ctaaactact ttttaaatag cttcctcttc catcaattta tttgtatatt actgatttaa
      241 ttcttcaagt aactgattgt ttcttgcaat acttcatcct aaactctgga aactttataa
      301 actacctctc tagcatttgg taaatttcca tctggaatac ctacagcaat accaaatggt
      361 acagaatacc cttctggtat atcaagtagt tctctatatt ttttatttgt atcaaacttc
      421 atctttattg actctgattc ttttacatct tctttatcca atacactcac aagaccttca
      481 atatcccctt gttcaacagg tgtaaataaa cctctaacca ttcctattat acaacttcca
      541 agccctagtg cttgtgcagc tgttgttata ttccctgtaa gtattcctat atcatatgga
      601 gcccatgaac tactttcatc ataagaaata aataaaacgg ttggagcacc ataaaataac
      661 ttaaagtttt tatttatctc aacattactc acctcatgaa tcctagataa agtatcatca
      721 ctaatctctt ttaaaagttt ctggtcttgc acaacagtta tgtgccaagg ctgtttatta
      781 catcctgaag gtgctgcaaa tgcacagtgt aataatgtgt ttacttgctc atcactaatt
      841 tgttctgtcg taaattttcg tatacttcta cgactttgta ttaaatttat tgtttggttg
      901 tcttgaaaat tattattcat atctattccc ctttttatgt atttcttagt acaaatacta
      961 aatcttcaga aaattaatct tataattaaa tttctttaca atattattat aattattttt
     1021 agcttgtatg tgaagactta aaaatataaa cacttttaat atatctcaat tatatatata
     1081 aatgaaaatc tggtattcgt catctataga aactgctctt ttctatagtt taatcaatac
     1141 cagattaata aaacatgata tattaattta aaggacccca tccctcttta gaatgaatct
     1201 ctgtttttac agacttaaca ctatctgtgt caacatccca tgacctacct gcaacagaaa
     1261 taccattttt acctttatac catctacctt catcataatc gtaaactagg gaagtatacc
     1321 aattacctcc agtcttatta tttgcaaata caactacagt agcatcagat ttagtaggat
     1381 tatatgcata tggttgtata tatagtgtat ccttacttaa tccatatttt gccttaaatt
     1441 catctggaat tgtaggccac ccatttttat atttattgtc taataaatat tttctaaaat
     1501 catcattgcc ctttgaagct cctggtatta tagaagggtc ttgtgcaaat gatgcaatca
     1561 aatctttcat actttgatgc acatccctag ccatttcaac accgtctgga tgttttgtac
     1621 aagtaacata cacttttgca atgctttcta ttccagttat tccatcataa ccatcatcaa
     1681 acgttgctga atatattcca cctgacttac actttggttc tgtttcaaag tacttaccat
     1741 ctttgttttc taatacctct tttatgactt cattcttgtc tttacttgat tcctcagcca
     1801 ttgcaataac aatttgagtc tttatatttt ctctattaga aagacatgta actgctttac
     1861 ttttttctat atttctaaat aacgctggaa cagctactat aactaaaatt cctattatag
     1921 atataactac caacaattca attaatgtaa aacccttttt attcataata atcattccca
     1981 ttaaataaaa ttatagtact tatttttaaa tactacatat taataaattg tctacataaa
     2041 tcctttcaac agaactacta atatacttac agaactacta atatactcaa tattcaattt
     2101 aataattaaa taacttgtat gctaaaactc aatatcctct acctctattt tgtcaatagc
     2161 atcctgtact aatttttcaa tgtcaagtgc tgtttcagat ttttctattt tctctaatct
     2221 aggtttagtg acgggctttc taggagaaaa tacactacaa caatcttctt caggcactat
     2281 agatgtttca aaagtcccta tttttttggc tatatcaact atatctgatt tatccattgc
     2341 tataagtggt ctaaacactg gtaagtctac aacggcatta gtacaagtaa gtccttgtat
     2401 agtttgagat gcaacctgcc caatactttc acctgtaatt aaagcatcac aatgtctttt
     2461 ttcagaaagt ctctgtgcta tcctcatcat aaatcttctt gaaagaatag tagcttcttc
     2521 ttcattacaa ttctcgccaa ttgctttttg tatttctaag atattaactt tatgaagcct
     2581 tactctacca cagtattttg ccagtatttt agctaaatcc ttaacttttt cctgtgacct
     2641 ttcacttgta aatggataac tatgaaagtg aactgcctct acttccatac ctctttttgc
     2701 aaccatccat gtagctactg ggctatctat acctcctgat aaaagagaca tagctctacc
     2761 attcgttcca agtggcaatc caccatatcc aggtatagta tcactataga ccatagtatg
     2821 aaattctctg tattcgcact ttattttaac ttctggattt cttacatcaa cattaatcct
     2881 atctcctacc tttgataata agtatccacc tatatccata ctcatttctt gagaagtcaa
     2941 tccgaaagac ttatctcctc ttcttgactc taccttaaaa gttttatatc cagcctctat
     3001 tttttcttct aacattttta aagctatttc ttttaatgta tcataatctt ttttagctct
     3061 tactccaggg cacacaccca ctatcccaaa tacttttcta acttcttcaa ttacttcttc
     3121 ataatcatag tcttctaaat caacatatat tcttccatac tctttatata cattaaatct
     3181 tccaattggt tttaacatat ttcttatatt tcttataagc ctattctcaa atatatatct
     3241 attctttcct tttactccaa tttctccata ctttactatt aatatattat acaccatttc
     3301 acctcttaaa ctaatttatt atcactattt atacagtatt ctttattttc ttttcattat
     3361 tgaccttaag tcacaaattg attctttcaa aactttcaca gcttctaaca tttcttcttc
     3421 tgtattcata tcagataaac taaatcttat tgttccattt atttcttcat ttgtaagacc
     3481 tatagcattt aatacgtaac tacctttctt tttagaagaa catgcagagc cagttgatac
     3541 ataaatacct ttttgctcta agtaatgaag taaaacttct ccttttgtcc ctctaaatga
     3601 tacatttaat atatgacata ctccatcttc tggagaattg atttttatat cttctatatt
     3661 atcaattatt tcatttttta atatattttt taagttatct actttcgaaa taacagcatc
     3721 taaatctttg tttagtattc taacagcttc tccaagacca tatattccag gtacattttc
     3781 tgttcccgac ctaattccaa tttcctgacc accacctgtt aacataggct taaggcgatt
     3841 attttctttt atatacataa atccaattcc ctttggacca tgaaatttat gtgcacttac
     3901 actcataaaa tctatattgt atttagatgg tctaaagtta atttttccat atgattgaat
     3961 agcatcaaca tggaaataaa ttttttcttt taaacccttc aaatactttc caacttcacc
     4021 tattggctgt atagttccta tttcattgtt aacatgcatc atgcttacta agcatgtagt
     4081 tgactttatc gcatttttta aatcctctat atttattttc ccatcttttc cgacctctaa
     4141 ataagttact tcaaaaccat cttcttctaa atcttttaat gtatttaaaa cagaaggatg
     4201 ttctatgtta gtagatatta tgtgattttt tcttttttta tttaaactag taatacctct
     4261 tattatagta ttattacact ctgtaccacc tgatgtaaaa taaatctcct tttctttcgc
     4321 tcctagagat ttagctatat cttgtcttac ttcttttata gctttttcaa cttctacacc
     4381 ttttctatgg acagaagaag gatttccata ttccgtatta agtgcataaa ccattttatc
     4441 tataacttct tgataaggtt ttgtagttgc gctattgtct aagtatattt ccaacttaat
     4501 tacacctacc tttatttaaa atcttcaact ctaactatta taccactaat tatagtattt
     4561 tttttgttaa tctttattaa aaagacaatc ttaaattata aaatattatt tcatgaaaag
     4621 ctagtttttt cactttatta caaattttta tagtaaaata taatatactt atactatacc
     4681 ctacaaaaat atattataaa atacaatata tgataaaata atatattata taaaataaat
     4741 atattatatt atacatatac ttatttttac tataaaagtt aaatttataa gcttacttgt
     4801 tataaaaata acttttataa tttatttcaa aaaaaatatt gatttttgtg tcgcattttg
     4861 ttataataaa ttaaggttat ccccctggta accctagtta gttaatatat ctattcccaa
     4921 taccctttca taaggatata ttttatattt attaaaaatc ggattagtaa cggaaattaa
     4981 ttcggtggaa aaaaagagct taccccgagc tctttttttt tctgcaaaaa atcgtaaaaa
     5041 taaagttaat attaatataa ctttaatttt aaaattaata ttaaccatca ctaaaaaagg
     5101 atgtattgaa tttctaatat caataacatc ctttttatat attatagcac ttttgctaaa
     5161 aatgcttttg ttctttcatg ttttggattt ccgaaaactt cttctggagt attatcttca
     5221 agtatacttc ctccatctat aaaaataact ctatctgcaa cttccttagc aaatcccatc
     5281 tcatgagtta caattgccat tgtcatacct tctttagcaa gttcttttat aacatccaaa
     5341 acttcgttta ccatttctgg gtcaagagca gatgttggct catcaaacaa catcatatct
     5401 ggttccatag caagtgctct agctattgct attctttgct tttgtcctcc agataattgt
     5461 gatggatatg aatctttttt atctaaaaga ccaactctac tcaacaaaat ttctgctttt
     5521 ttttctgctt cttccttagt catctttttt aatttaattg gtgctaatgt tatattatct
     5581 aaaatagtct tatgtgggaa taaattaaag ttctgaaaca ccatacctat attttgtcta
     5641 acctcatcaa tattagtttt tttatcgacc aaattttttc cttcaaatat tatttctcca
     5701 cctgtaggta tttctagtaa attcatacat ctaagaagtg tacttttacc agaaccactt
     5761 ggacctacta taaccattat ttcgccttta gcgatttcta agtctatatt ttttaataca
     5821 tttaaatctc caaaagattt acttaaattt tttattgtaa tcatattatc actttccttt
     5881 ttactattct atgttttccc taaatgctaa acatgctctc atctagttag acacagatag
     5941 tttcttttct aataatccaa ctaatcttga tagagtaaat gttataacaa agtaaattgc
     6001 tgctgctact attaatggct ctaatgctct aaatgctgca ttttttacta tatcagcagt
     6061 acgcattatc tcaacaactc ctattacaga tattattgaa gattctttta caagtgtaat
     6121 aaactcattt gctaatgaag gtaatatatt ttttatagct tgaggtatta ttatatatct
     6181 catagttgac caataattta atcctaatga tctacttgct tccatttgtc cattatcaac
     6241 tgattgtata cctgatctaa gtatctctgc cacgtatgca ccagagttta ctgataatgc
     6301 aaatgcacta gctataaatt cacttggtat accaaacaac atagggaatc ttattcctaa
     6361 ttgaggtaaa ccaaaccata ctatatatat ctgtactaat aatggtgtcc ctcttaaaac
     6421 ctcaatatag attgatgata ttgctcttaa tactttgctc tttgatattt ttgccataca
     6481 gataattata cctattataa atccaaagca taatgccaca agagaaattg atactgtcac
     6541 acctgttcct tccaaaaaag aagtcccaaa tctacttaaa aaactaaaat ctaaactcat
     6601 aatttcatct cccacataac tttcttacta atttgaagca gcttcagtag atgcttcatt
     6661 taaaaattct tctatcttct tgccatcttg taattctttt atctttttgt ttaataattc
     6721 tataaaatct ttgttattgt cagatttttt gattgctgct gccatacctt ctgttacatc
     6781 tttcccaact tcagtatttg ccatttttat tccatcatat tttttaacat ttattaaaga
     6841 aactgcttca ttagtaacaa ctgcatctat gtttccattt tttaattctg taattaaatc
     6901 aggtattgct ttcaaagatt ttgtagttgt catttttaaa gtgttaacta catattcttc
     6961 ttggatactt cctgcttgaa ctccaactct aagtttcttt aaatcatctt cagtttttac
     7021 tttgtctata tctgcatctt taactataac tgcatttcta cttaaataat ataattctga
     7081 aaaatcaaca ctcttttctc tctctggtgt tggagacata cctgcaagaa caatatcaac
     7141 ttggtctgca tttaaagcac ctattaatcc atcaaatgac atatccttaa tttcaacctt
     7201 tacaccaagc tcttttgcaa attcttcagc caacattata tcgaatcctt ttattgaatc
     7261 ttttccatct actaccttat gaaattcaaa tggaggaaat tctgcactag taccaacaac
     7321 taattttcca ttgtctttta tttgttctaa ctttgttttt tctcctccac cactacatcc
     7381 tactagcgat aatgtcaatc ctaatactaa tcctaaactt aataattttt taaatacttt
     7441 cattttaact acccctctct tttaattata atttccctca gattttaata cttaaatgtt
     7501 tcgagttaca aaaaaagtct ctcagtcttt aatgactaag agacgacttt accgcgttac
     7561 cactcttatt gataaatact tatattactt tcaaaatttg tgactgttag cttttaagct
     7621 gtatggatat ttttatttta aaatcaaaaa agtcccttag ctttacagct aagagacgaa
     7681 ttatatccgc gttaccactc tttttgataa gtaagtactt atcctctcaa tcccttaagg
     7741 cgggtaaacc aattatcata ctaaagtttc tgataatctc ctccagagct ctcttcacat
     7801 agacttcatt gctaggctta caccaacccc taactcgctg taaatccata tatgctactt
     7861 tctctatcat tggatttgtt tccttaaatt gttaatacaa ttgtacttcc ttataatatt
     7921 tttgtcaata agttttttat ttttttaata atttttactt gtaaattatc taaatactac
     7981 tgtttatatt tattgatatt atttgtgtaa ttataaatag tatatttcat atttttagct
     8041 atttcttaaa taatactaaa taatatcttt cacattgttg cttttcttta ataatactaa
     8101 ataatatttt ccacattgtt gctttttcta aacaactata aataatatat taaaccctta
     8161 tttctttttc taataagtta aataatacac tttacacata tctatttgtc ttgcacataa
     8221 taaataatac attatatttc tatctaaatt tagattctaa attaaatagt ataaattata
     8281 ttcttcaata aacaagtttt caaatccagg attcgctctc tatctttaaa ctttattgta
     8341 aacataattc catctttttt aattatttct ccttcatgaa attttttatg gtatacctta
     8401 tctcctacac caatactgtc aatttctttt ttcgttggag attttatatc attaataaat
     8461 aatgatttat caactttctt accatactta tttaaagtag agcttataca taacttttct
     8521 tcagctcttg taatagcaac atacataagt cttctttctt cttctaattg ttcttctttt
     8581 ttctcttcct tacaaatatc atatgatttt tcatgaggta ttgttccttc atttacacct
     8641 ataatataaa catttctaaa ttctaatcct tttgcactat gcatagttgt aaatatgaca
     8701 ccctcagtct gcttattctt gttattttcc gttaactcag tctttactct atcaatatgc
     8761 tctaaaaact ctgtaacagt attaaaatta gttgctgaac tctcaagttc atttaatatc
     8821 tctacaagtc cattagtctt tatctttctg ttgctacaat aatctaaaac atatctatca
     8881 taatcaagac tagttctaat ataagatatt gcatttttag gatttaaagt atttaaataa
     8941 cttaaatcta tttccaaatc atttattgtt ttaacttgtt taggatgaag attacactta
     9001 tttattaatg ctgttataaa gtcattttca tccttaacca tatttatact gtctttggat
     9061 atatatctaa aaggcttgtt tataattctc aaccaatctt tatttgattt tggattaata
     9121 cctattctta aataggctag tatgtcttga cttgcccaat ggtcatatat tgtaattact
     9181 gagtctttta ctacaaatgg aatcctcata tccataaata catctactaa tgctcttgac
     9241 tgtatattag ttctataaat tactgcaaaa tctgaatact ctacataatc tttttgtatt
     9301 tcgtcaatta tttccctggc aatatataag gcttcttcct ctgaatcatg cggagaaata
     9361 taggtaacac ttcctccatc cccctgacta cacttaatga ttttttcata tctattttta
     9421 tttttgtcga taagtctatt tgcagtatgc actatctcac ttttagacct gtaatttata
     9481 tctaatatta tttttttagt attattaaag tattgttcaa attcaagcaa aaaatctggt
     9541 ctagcacctc taaatccata tatactttgg tcttcatctc caactgcaaa tatattgttt
     9601 aatgggctac aaattaactt taaaacttca aactgtactt tatttatatc ttgaaattca
     9661 tctatcaata tatatttata cacatttcta accatttcta gtgcagactt attgttcaaa
     9721 agtaaataat aagttcttat aagcatatca tcaaaatcta ttttattaac tttagatttt
     9781 tgttcttcgt ataagttgta tacttttaaa aactcatctt ttgttaatac ttctgaatta
     9841 aattcatttt tatccataag ttcatttttt acataggaaa tttcatttat aacttgtcct
     9901 atattctcat catcatcagc attctctata tttaaacttt ttaggattgc cttgattgtc
     9961 attcgctttg acttttcatc aaatatactg tctaagttgt atctttcaaa gtatcttaga
    10021 attttaaaaa atacagagtg aaaagtacca taggttacct tattaagtct tatatcatca
    10081 cttaaattca aagctctatt tttcatttct attgaagatg ccttggtaaa acttattgcc
    10141 aagattcttg ttggtgctat gtttttgttt acaaccatat tggctattct atatgtaatt
    10201 actctggtct tacctgaacc aggccctgca agtatcatgc aaggcccatc tatatgctca
    10261 actgcttcta attgattttc atttaacttt cttatatcta tatttgttgt gattattagc
    10321 tccaccacct tgatttataa ttatattatt ttctttttaa ttataaacta aaagttcata
    10381 aaaataaatt taatttttcc tctattaaac cacatcattc ctattttcat gacatatctt
    10441 gagttctttt ttaattttgt cgcttatatc ttcaggtata aatgatggtt tactaatata
    10501 gtagccttgc atataatcta ctccaagatt aattagtgtt tccatttcac cttttgtttc
    10561 tacaccttct gctatcactt taatatttct ttcgttagaa tatgagataa gattttttaa
    10621 tattttctgt ctgttttcat ctttatcaat acctcttaca atagacatat caatctttac
    10681 atagtctggc attatatata atagtacagc atctccgttg taacctgtcc caaagtcatc
    10741 taaagcaatt tctatattcc aatggtctat atatgctttc tttttctcaa taaaatcttc
    10801 attaatctta tcattctctg ttatttctag tactactcta tttaaatatt caccatataa
    10861 atcttcaatt tcctcaaaat ctacttttga caaattatta ttaggaatag aatttaagaa
    10921 cagtttgcaa tcgccaaatt tttctttgta ttttttaaat gatttaagtg ctttaaacca
    10981 tgtaatacgc tcaatttgat ataatttaga ctgtgaacga gctaatctaa tgacatctat
    11041 tggtgaacta aaagttttta ttttaggtct cataagtgct tcatatgcaa aaactttacc
    11101 tttacaatct acaataggct gaaatgcata ctcaactaat tgaccatcaa ttaacttgtt
    11161 taattcttct ctattactca ataagaatga atccttatta tatatattaa tatcaaattc
    11221 actaacttca cccttgattg tatttttaat ttgatacata gcaaaatctg cgtatctcat
    11281 taattcatca tagttggttg aatcatcagg gtaccaggaa attcctgctg atgcccttat
    11341 tttaaattct gttccatcat gaagttttaa taaggtatta ttcatctgtt tcttaacaga
    11401 attaataata tctcttatac tatctttact ttcatatcca tatataaata cataaaactc
    11461 atcacctgaa agtctagata ctataccatt ccatgatata aacttcttaa gtatgtctgc
    11521 agcacaccta atatattcat caccagcatc atgtccatat gtatcattaa tatattttag
    11581 attatctaaa tcccacataa taaatgctgc tatcttaagt tcatctttat tcttaaattt
    11641 ttcttgtatc tgtgaatgaa aagctctcct atttaaaaga ttcgttaaaa tatcaaaatc
    11701 tctttcatat tctatcttcc ttttctcaat aaattctttt gttacatcaa caacaacacc
    11761 aagaaccttt agctcatctt caaagatatt cattcttatc cacttaagtt ttttatcttt
    11821 agattcaaac ttatatatat atgtattttc tgtttcataa ctttcttgca aatatttatc
    11881 tagtcccctt aattttttca ggaacttatt tttttccata tatccatatt cttcaaattt
    11941 gatttcagta gtaaacacgc taaaaaattc ttttgtacaa aaaacattct ctgcgttttt
    12001 gtataactca aaagctccaa ttggcatatc taccatttca ataatctgtg ataattttga
    12061 cgaagaatct gcaacatttg cactgagcaa ctctatagct gaagataatt catctatttc
    12121 agatatattt atcttatcaa gatttactgg ttttgatgga ttactgtttc taactttgtt
    12181 ggctaaaaga acaattggtt ttgtaaataa tcttgatgca atataaatac ctattagacc
    12241 tattaataaa gaaattgcta tagatattat aactaatttc tctacccttt ttgaaaatga
    12301 caaaagactt ttttcttcaa taatacccaa aagagcccaa cgttcatttt caaatggagt
    12361 attggagtta tataaatcta agtattgtac actagcataa atgttgccat taccacattc
    12421 attatcttta tttttaatct tatatatatt tttatacgat tccttctgct ctaaattaga
    12481 atgtaaacca tcccaaaatt tttcttttaa tgagtatcca tttgaaatta cattttcaaa
    12541 ggccatatca ttatttctat ctacacctaa aatataatta ccctttttat tcccatttat
    12601 ctctgagtat ggaagtaatt ctcttaaata atttacactt aaatctattc caagtactcc
    12661 atatacagtt ccatcttcat aaataagggg aactgtatat gtcataagcc tatcacctgc
    12721 atttgtcaat aaaaacttac ttccccagta tcctaaatta gaacttgata catttggatt
    12781 atcaattgca gctctaaatg gtttataaaa aaaatcatct ccatcttgct cattttcact
    12841 tttaaatgaa aacttaggtt cccaataact gtccatagat attccaaaac ttcttgctat
    12901 atctgatgaa cctctctcaa ttaacaaatc agaattatca tttggattaa acttagggtc
    12961 taaatccctt atatacaatc ctgtcctact tatttcacct ttactatcta ttgacttatc
    13021 gttaatattt ttgtcactta ggattataaa agctcctgta acagaatttt ttctcaaaag
    13081 atatattaaa tcatttgata tgctttttat aatatctttg ttaatttctt cattgttgcc
    13141 tacatcctca attaaggaat ttttttcatt taatactttt tttacagagg aattaattgt
    13201 agcttccgtt tcacttgtat ttgaccatct ttgtaacatt tcattttgta tataattttt
    13261 acgattaatt actctttcat ttaagatgtc aaacgaatta tcatttaatt tcttaatagt
    13321 tcctccccat aaaattgtgg cacaaaataa acttgtttga attagcataa caataattag
    13381 gggaaatatc atctttttca ttattgaatt gttttttctt agattgtttt ccatacccat
    13441 tccacctata cctttgtgct cgtcaacaca ctaactgcca attcatctat ttttttatag
    13501 cattttcaag ctcagcctta aaattttcaa accaagtttt aaaattttta tcattattaa
    13561 attgtgctac tgcatccttc ttagaagttc cactttttac taattcattt attttatttg
    13621 aatcttcttt agctttatca agcattgaat attcaagtat ttgtctagct ttagttccac
    13681 catcaaatgc tttattagta tataaattac aactgttaat ctgttcaata gatgaggcta
    13741 ttgaaccttc aactttatca gataaactca aattatcttt cttcataact tcttttataa
    13801 catccaaatc attcgttttt ttctttactg gtaagtatcc agaagcaata gagaatttta
    13861 tattaggttc tttatctgta aaccatttta aaaattctac tgatgcatat tcttcttctt
    13921 tagtagattt tgttacagcc attcctgcac cttgttgtac agcatatttt ccttctcctt
    13981 taaaacgtgg tgcttgaaaa acagatgttt caatattata actctcatta tcatttagca
    14041 ttactctatc tggaaagtat gctgctcctg aactagaacc tacaagagct aatatatcac
    14101 ctgtttttgc atcatcagaa cgaaacttac cataagaagc aaaatatcca tttatatatg
    14161 gtacatagaa attatcccat agttttttca taactttttc atcaatattt agtgtaactt
    14221 taccatcttt aacagaaaaa atttctactc ctagttgttt acttcctata ataatataat
    14281 ttgctaaagc atctcttcca aaaaatgctt taccatcatt aggctctttc gttaaactat
    14341 ctgtccattc ataatatttt tttgatgtct ctactaatcc ttcaattgtt tttatatcat
    14401 ttatatttga atttgtagct tttgcaaatt tatcccaatc agttttattt aacatcaaaa
    14461 tttcagttga ttttgcaatt gggaaaagtt taaactcatc cttagaattt attctgcctt
    14521 cttctacata ttcgtctatg tattcattta attcttcttt acttatgtac ttatccatat
    14581 ctactagtaa ccctaattta tccatttcat atgcagtatc tgagtatgct gcaaatatat
    14641 ttggtacatc ttcagaacca acttttttat ttgcagaatc taaaactttc tctgataaat
    14701 caactacatt accttgactg aatgcttcaa caataattcc tttttcagca cctacagtgt
    14761 cattaaattc cttaacaagc ttatcaaaag ccattttctg ctgtccatta taataatgcc
    14821 aaatttgtat tgatgtcgga ttttctgggt ctaacttata attatcttcc ttctttaaac
    14881 tacatcctgt aagtaataaa acaatcattg atgtgataat taattttgca aacttacacc
    14941 tattcataaa atctactcct tcaaattata aaatttataa tagcattaaa actgtaactt
    15001 cactatttat attaattata gaacgtttat tgatatattt aaacaggatt tacaacatat
    15061 ttaaaagcaa ttaagaaaca tactattaca aatatagaaa ataaagcttt tacataattt
    15121 ttatttctaa atgcaccaaa tgacaccaat ccttgttgaa tagctactgt aattactaaa
    15181 agtatcatta ttatattaag ttgaaccagt ttaaataagt aaagcaatga aaacactact
    15241 agaagtacac ataatacaat actagattta ttaataatat catcaatctt atctaccttc
    15301 ttagattgct tattaatttt atttaatttt tctttattta aattctcaac ttttttatta
    15361 tacctttctc ttgttttatc tttatattta gtatttttat ttttatttcc catttatttt
    15421 ccatcctcta taaatttttt aattgagctt atacattatt taaatattat atatttaaga
    15481 taccatatat tcctacaaaa aggtaactta ctatgtatct atttttgatt ttcgcataaa
    15541 aaagccatct cctttagaat taattctgta ttgagacagc taatttaact atttatcctt
    15601 tgaaacattt tctacattat catatttact atcaactaaa actatatcaa ctcttctatt
    15661 ttttgaccta ccttcttcag atgaattttc tgctattggt ctaaactcac catatcctac
    15721 agcagataat ttatctggtg ctatacctgc attgtcaata agaagttgaa caacattggt
    15781 tgctctcata actgataaat cccaatttga cttaaactct gaatttttta tagacatatt
    15841 gtctgtatgg ccttctactc tcatgtaact attcatttca tttaacatct tacctatttg
    15901 aataatctta tctctagaat tatccttcac aatagctttc cctgtatcaa atagtattgt
    15961 atctttaagg cttattacta atcctctatc ttgaactctt aatgatactg aattagccat
    16021 accattttcg tttaaatact tctgaatttc ttcaccaaat tttttaaact tagcattttg
    16081 taaagtatct aaatcattac ttcctggttc aactactggt tctatcttgc tattaccacc
    16141 ttcaataact ccagaagaac caccaaaagc agaatttaga gattgagata attgtttata
    16201 tttctccgca tcaacattac tcatagaata cattattaca aagaaaatca taagtaatgt
    16261 tatgaggtct gaataagtta aaagccatcg ctcattgttt tcttcttttt catcttcatc
    16321 atacaacata aacattccat ccttttatat tattcagctc taccaccaat ttcttcaagt
    16381 tcaattagtt cttttgaatt taaaaatatt tttaattttt ctgtcattaa attagaatta
    16441 tcaccctcaa gtatggataa tattgcttct atcaccaaaa gtctttcact tacttcttgt
    16501 tgatttatag ccttaagttt tgatgctatt ggtaaccata ttaaattggc agaaccaaca
    16561 ccatacaaag tagccaaaaa tgcaacagaa atttgaggtc ctaatgcatc tggattactt
    16621 gaaagattac ctaaaatatg tactaatccc ataactgtac ctattatccc cagtgtaggt
    16681 gcatatccac ctgctgaatc aaaaattgct attccttctt tatgtcgttt tgatgttatc
    16741 tgtatctgtg attccaatat atttcttata gtaactgcat ccactccatc taccataagt
    16801 tcaagccctt ttctaataaa agggtctaat tcatcattct cacttatttc tttgtcaata
    16861 ctaagaagcc cctctttcct agcctttgtt gcaatttctt tgaaatagat tatattttct
    16921 atgttattag gctttttatt tttaaaagct aataacatta tctttataga ctttttaaac
    16981 acagggaatg gagtcgaagc tccaacagct cctatagttc caccaaacac aacaagtgct
    17041 gatgaaaata caaataatgc tccaacatgt cccccatcaa taacaaaagc aactaccaaa
    17101 gatgctatcc ccactatgaa aaaaattaaa gttgtcatct attccctcct ttctttagtt
    17161 atacatatct aatcatttat gacattataa aaagactatc tttaataaaa atagccttta
    17221 ataattggcg gagaaggagg gattcgaacc ctcgcaccgg ttacccagcc taatccctta
    17281 gcaggggatc ctcttgagcc acttgagtac ttctccatat ctctatacta gtaaattata
    17341 taataaaatc atattttagt caattgtttt ataaaatttg agttattttg aattattaaa
    17401 catctatttt tacttttttg cttaaatgta agttttaaat atggtaaaat tatcttgcat
    17461 aacacttata atattatttg ataaatatac atacattaac aaatatacct aaactctgac
    17521 ttaatagata taataacagg tgttggtggt aaagctcttg gagcatttcc aggttctgca
    17581 tacctttgtg ctaaagagag tattttacaa aatattaaag aaaatcaatg taagaatgtg
    17641 tatcttaatc tttataaaca ctataaagtt gctaaatcat cttctcaaac accaaataca
    17701 cctaatgtta ctttaatatt tgcccttaat gaagctttaa ctgagttttt ggaagatgac
    17761 agtaaaatag aaagatacaa agaatgttct gctattttaa ggaatggtat ggaagaattg
    17821 ggtctaacat ttttacttcc agataagtat atgtctaata cagtaacatc tgtatttcta
    17881 cctaaagaaa tcaatgtaaa tgagtttata ttagggctag aaagggaaag tggctatgtt
    17941 gtctatccag gaaaaggcaa attcctagat gctaacatat tccaagtagc aaatatggga
    18001 gaaatatatc cagaagattg ttataaattc ttagatatct taaaatcaaa attggagata
    18061 aaaaaagtta tataacagtt tgtttgtaaa atcctacaat atatcagtat aaattaaata
    18121 gactgatttt tttaaatttt cctataataa attatatttt atatttttgt ataagggtga
    18181 actataatat gtaaagttca cccctatttc aaatcttttt ccttcaatat aatctttttc
    18241 ttttaattta ttttatattt ttgacataat tattcttaca tttaattgtt ttttattttt
    18301 gacgcaatcg ttttttattc agtcatttta tattcttgat acaatcattc ttacacttaa
    18361 ttatttttta tttttgacac aatcgttttt tgttgaatca ttttatattc ttgatacaat
    18421 cattcttaca cttaattatt ttttgttttt gacacaatcg ttttttattc agtcatttaa
    18481 tattttcaac acaatcattc ttacattcta ttattgtttg tttttgatac aactgttttt
    18541 attcagtcat ttaatattct tgacacaatt attcttacat tctattattg tttatttttg
    18601 acgcaatcgt tttttattca gtcatttaat actttcgaca caatcatttt tacattctat
    18661 tattgtttgt tttgatacaa ctgtttttat tcagtcattt tatattttcg acataattat
    18721 tcttacattc tattattgtt tatttttgac gcaatcgttt tttattcagt cattttatat
    18781 tttcgacaca atcattctta cattctatta ttgtttgttt ttgatacaac tgtttttatt
    18841 cagtcattta atattctcaa cacaattacc ttttcattca atcaaagtaa tctttaagca
    18901 ttatttttca agctcatcaa agtaattata tacgataacc tcacctgtct ctttatctgt
    18961 agtctttata atgcccttag ctccatttac ctcttctttt gtaaattcat catctagcac
    19021 aactttgaat ttatcttcct ttccataacc ttgttgaaat tcatctctca aaattgcatt
    19081 tttttctgct tttggcttca actcaaattc aattccagat ttcatttcat caaaataatt
    19141 taatactaca acctcattat tcattttatt agttgtcttt ataatccctt tagctccatt
    19201 tacttcttct tttgtaaatt catcatccaa tgttatatta aatttgtctt cttttccata
    19261 ttcctcttga aaatccctct tcatttcatt gtatttagtt tcaaactctt tactcttgtt
    19321 taattccata gctgatacat ttgtcaatga tgctccaatt gccattactg ttaatgccat
    19381 tactatacca cttttaaatt tttttacttt catatcttac ctcctaaatt aaatgttctc
    19441 aatgaaatta tataaagaaa atcctaagtt ttacagtttc attcttgtaa ctaaaattac
    19501 tattatgtaa ccaaactttt tgcttcaact attccttaaa agttgctttt ttgaggaata
    19561 gttgaagtta aataattaga ttttatctat atttatagat ttaaaatcaa atttatccat
    19621 ataaataaat acttattttt gcaaaataaa aatttttaat tactccaatc cttcttattt
    19681 acttaaaatc ctatgataag aaatttaaaa gtctttacct tctttaacaa taatttattt
    19741 acttttaaca tacaaaatat agagagtata tcaaaatcat tttactgaat attctaaaaa
    19801 taagtacccc ctattagtat atatatttac atattaaaaa aaagttttaa ataaagttat
    19861 attttttaca acagttttgt aattaaaaac atattgaagg taaatttaaa ggtactatat
    19921 actataaata tgtcgacaca ataaatttaa aaaggagaac taaatatgaa aaaaagatta
    19981 ataataatga tattgtctgt tgtcttagta ctatcaagta tacttacgat atttgcatat
    20041 tcaaatatta aatataataa taataataaa ttgatatatt ctaatatgat agataaaaaa
    20101 actcaaaata gtgtaaagga aatcctaaaa gaaaataaaa ttaatgaaaa agacatagat
    20161 acatttatta aagcagtcaa caattataat aaattgcaag ttaaaatact tcaaaataat
    20221 ataaatatat ctaaatctgg atattcttca atcaatgcaa aacaagttcc atataaccta
    20281 gaaaaattgc aagataattg ggtgaaaaaa ttccctgatt atatggatgt aaattgtaga
    20341 ataactgctt ttagactttt taaagatttt ataaattcaa ataagaaatt tactggagac
    20401 tctattgact tgaatgtcga cttggacact ataatgaata ataaagatgc taaatttagc
    20461 accaaagatg tagaaaaatt tatcaacttc ttttctgcaa taccagctaa agatacagat
    20521 gatacaatca aaatttcaga acaaataaaa aatgaatgga aaaaaagaaa aatatctttt
    20581 aaaaataata aaaatatatc tattataaat ggatttcttc gttatccaga aactaaaaac
    20641 gtatttatag gtcatacagg catatgcatt aaaactaaaa atggcattct atttttagaa
    20701 aaatatggtg ttacatcacc ttatcaagtt actaaattta aaaataaaga agatgtaaaa
    20761 aattatatgt ttaatagatt gaagatgtca gaaggtgaaa ttgaattacc tgaccctata
    20821 ataatggaaa acgataaact tatgaaataa taactttaaa cgcaaaatag tatttataat
    20881 tactaagtca atataataga gaaggtctat agatttgtgt aaatacaagc ttatctacaa
    20941 tcttatataa gaatgtttat ataaataaga tagattaatc ctaagtccta ttattctatt
    21001 gaattttatt attattttat ttagattcta ttgttatttt acttagaact tattattatt
    21061 ttatttaagt tctattacta ttttcaatca tataaattta caaaagactg tacataaatt
    21121 tattttatac aaacttatct acagtctttt gtgtgaatat atctaaataa tatcgtattt
    21181 atttatttcc tctgcacagt gagaatcaga acctaaaact aatggaatat cgtatttttt
    21241 taccaactct aataagtatc catctatata aggctctttg cagtactctt ttctatttcc
    21301 agaaacatta taatcaagtt cataaccttt ttctttaatt aactttatta actcttcaag
    21361 aattgtattt cctttataat cgtatggaaa tacctgatta aactttctaa ctaaatttaa
    21421 atgacctatt ctttttggtt tatgtatacc taaatctgaa tttacagctt ttatcaatgt
    21481 ttcataatac ttattataaa cagcttcaat acttcctaat ttgtcgatta aattttgaaa
    21541 ctcctctaca ctgtaatcta cacaataata atcatcatca atcttaatta tatgtactga
    21601 taaaagagaa tcctctaatt cctttccata tttatttaaa ttctccttta tcccttcttc
    21661 gtatccttct ataaaatcca cttccgaccc aacatttatc ttgattttac cctcatactt
    21721 ttctttcaac ttcttgacat cattaaaata ctttggtaaa tcttcaatac tcatacaact
    21781 atcattttca ggagcagggt ctctaaatcc atttgcatac ggaaaatgtt ctgtaaatgt
    21841 catttctgtt attccaacat ccattgctct ttgtacatat ttttcaaaat catccttact
    21901 tccatgagga caataaggtg aatgtatatg accatctttc ataaataatt cactcctttt
    21961 ttaaagaaaa aatctaatat aaatgcataa atcttttaac ttcaaaataa tatttttaat
    22021 catgctaatt tttattatat ctaatattag agtaatttta aactgccttt taagtatctt
    22081 atcattagta ctattttcaa cttaacatta atattatttt ttaacttaac attaatatta
    22141 ttttttaact taacattaat actatcttta aatagtaata ctcaatatat aattacttaa
    22201 cataaaataa ctcaaattgc ttgatgaggc ttttgcagta tttaaagaat atataattat
    22261 ttaacattaa ataatccaat cttgtaataa aatttactca ttaaagtata ttacagaaaa
    22321 tacctcaaaa taaacttttt agttcatgag atactctttt ttacatgaaa ttagatatat
    22381 ttttatcatt tcaacaatga aagggaggct tatatccatc tttagacaac cccttagata
    22441 aaatttttaa taattaaaca tcacaaaata taaaaatcgc ttatatcaaa cgtataagcg
    22501 attaattata tttacatatg ttttttagcc tctaacaaca ttttattagc ttcttccata
    22561 tactctatag ccttttcaat actctttgct gtttcttctt ttccaatagc tctagccttt
    22621 tcaacccact ctctaaatcc ttcttcatga gtttcattgt gatttatcca atgtactaaa
    22681 agtattttta aagttttttc atccttagac tctgatgatt cctcatgact atgttcgtgg
    22741 tcgtggtcgt gagcatggtc atgtggatgt tcatgacata tatctccatg agtatgttcg
    22801 tggcagtggt catggtcatg atgtccatga tgatatctta caatctcttt atcaaaaatc
    22861 attagttatt ccccctgtta ttttatatta aactcttttt ttataaggtt tacagaatct
    22921 tttacaagta gtgctaatgg tttaccttct aatccaacta actccacatt ttctggcata
    22981 ataggtaaaa gtatcttaag tgcctcactg tctgcaatag cttcacttat attacaagta
    23041 acttctccca tcatagaatt aggtattatt acagaaatag gtgcaactat tatatttgct
    23101 tttttagctg atactactat agcattttcc cctgtagctc ctttattagc atgagctttc
    23161 atcatagaac tagttgctat agaattagtc cctagtgcat aaatttctac atatgtaggt
    23221 aactcttctc tcaaagaaga aactatctgg gctccaatac ctccacccat tccatctatc
    23281 actgctatta tcatatgaaa ttcccctatt aattaatttt cttgtattat tatcttatgg
    23341 tccatcaatc ttatttcttt aattatccca tctattatct tttgctctcc taataaatcc
    23401 gttaaataaa tctttccatc acaagggtct atattaacca cattttccat aaccttttct
    23461 aactcattat tacttttaca aatgaaagct gatgattcac acatataaat ctcctcctaa
    23521 tatgattttt attaaaaatc aaaaaaagat tcccttaggt atttcaataa accaaagaaa
    23581 ccttcatgat ttcagttttt gtatattatt ataccttaag tatatcactt taatttatgt
    23641 aaagtcaatt aaagttaacg ctttttatta tactcttcat tcttgtattt ttcatatagt
    23701 tctttaacta attgcttctc ataatcagtc aaatctccct ccacaaactc aacattaaat
    23761 tgttcagcta atccctttac tatgtttttc tgtagaatat ctatgtctat ttttctgcca
    23821 atttcatttt ctattccact tgctttttta gctgtaaatt tcatagctct ttctttcaat
    23881 tctggcgtct tagtttttat taatttaaac aatttttcta catcaaaatc cagtattatt
    23941 gaaccatgtt gtaataaaac accatctttt ctgctttgag cacttccaat taccttctta
    24001 ttattaatag taacttcata tgatgcatgt gcattaaaac atgcagctga taaattttcc
    24061 ctacttattc tctcgcctct atttaaatta tctgtttcta taccacttag attcaatcct
    24121 ttaactagac cttcacttat atatctataa gataggttga tgctcttatc gattaaagga
    24181 ttatcttctc ctataattat actataggtt agctcattat catgtaatac agctcttcca
    24241 cctgtaattc ttctagtata gtctatattc atacatctac acttatctaa atctatctca
    24301 tcttccaatt tctgaaaata tcctatactc aaacaagctg gttcccatgt ataaaatcta
    24361 agagttggct tattatgtcc tttcttatat gcagtaaata tagcttcgtc aattgccata
    24421 ttcattgctc cttcatatga tttattatgt ataactctcc actgattcat gattattacg
    24481 cccccatttt tagtataaat atatcctaga aatcctctat agatttattt ctcttattgc
    24541 taaatctatc tcactttgat ttaaaggtct tgaatagttg tatatagtac ttcctggtct
    24601 ttcattatag tatggtctat tacaatcctt acaacctctt atttcaaaag gatagccttt
    24661 gtttatgtct tttaaaatat cattgtcaag ctttatacta tttaagtatc catttttaaa
    24721 cttaaaatac tcttttggat aacctttatt tatcatataa gacattaact gtacccttct
    24781 ataactttct atgcttggtt gacttatctt ttccatttta gttcctctaa ctggagtaaa
    24841 tgcaaataaa ctaatcatta catcattttc ctttaaataa gtatataaat tgtatatatc
    24901 ttcatgactt tcacccatac caactattat atgtgtactt attttattgg gatatgattt
    24961 tgacatttca gttataaatt ttaacttttc atcatagtta tttcctttta ttttttcata
    25021 tagttcttta tttgctgcat ctattgctat tcctatttta tcaactccta ctgaaaaaaa
    25081 cttctttatc tgttcatcat tttctaattt tgcagatagt gaaattggca tgtctatcct
    25141 accacttata tagtttataa agtctaaaac agagttatgt gcttcttcac ttgccattga
    25201 ttgaatacat attctcttta tattttttcc tttataagct tttaaagcat ctaatatttc
    25261 ttcttttgaa aactctggcc aaattactct tgataattta tcttttctag tactactttc
    25321 tattgattga gaacaaaaac tgcatttatt tatgcatttt tctccaatca ttatatatgc
    25381 tgtggtagga ggtatatcgc tttttttgtt taatatccca agttctattg ctgtcccaac
    25441 tgatagtcta atcataaaac gcaacactcc ttacactcat ttattgtcat attcatttct
    25501 atagccttat tctttgcaga ccttgatggt aatactattc tattgactcc acacattata
    25561 gataattggt ctagctcttt tctatacact cctcttggtc tcatacaacc tagattaatt
    25621 tcagtatctg gtaaattaat tctagcttca cataaaatat ctgctacccc ttctaactca
    25681 ggaggttcta cattttcata ctcagttcct tttgttggaa taaggactat aaatgtaagc
    25741 ttattaggag gatttttttg taggtattct ataatttcat attcaccctt tatttgtcct
    25801 ccttttaaac caatacatat atgtggtgct acttctgtat gttcttgtat tgtattatag
    25861 acttcaatat aatcttcttt actctttttc atcttataaa cttctcttat tgtctcatca
    25921 tcaaacacta aatcaaaaga aactatatct aaatacttac acaactctac aatgctatct
    25981 ttatccataa gacctaaatg agcattcaat ctatatcctt gctcttttaa gtttttaatg
    26041 gtattaatat gagtatttat agggacatct ccctcataac tacaaccgcc actcaataga
    26101 aagctagtta tattccttga ttgtactttt tcctcatatt cttctattgg caccatattg
    26161 tttaagtagt gaccgttgca atgggcacat ttcaaactac attgattgct tgtagtacta
    26221 agagctagtg tctggttagg ataagcaaac tctattttat ttccaaaatt ctttaattta
    26281 atatcaaatg ctattttcat tttttcagat agattcttat tcatagttta ttccttctta
    26341 agtacatttt actcttctag taatttcttt gctgttggga actgctctat attcgtatgt
    26401 ggtaagaaac atgcagaaat aaattcatcc atataacttg gatatacact aagttcaaca
    26461 taagttattt gattacctat ttcttcaagt ttattttttg catctttact tataagagct
    26521 aagtaagaac caacaagtga actattccct atataagtaa atttttctct atcgatatca
    26581 ggaagtaacc ctataattat tgagttttct atgtctaggt tgtttcctat accacctgct
    26641 atataaaccc tatctaatat actaaaatcc atacctaaac tatctacaag agtgtatgcg
    26701 cctgaatata tagctccttt agctctgatg aaattatcta tatcaacttc attgactact
    26761 atatcatttt ctaaatcaaa ttcttcttta aatgctaata catactctcc tatctcatgc
    26821 tcattaaatc taactctctt attatctaaa tccctgtata ttttacctct tctatctatt
    26881 acacctttag taatcatttg acagattaaa tcaattatac cagaaccaca tataccaact
    26941 ggtgcacatt catcaataat ctttaatgtt ggctctaaag tatctttatc aataattact
    27001 ttctctattg ctcctgctga tgctctcatt ccacagctta tccctccacc ttcaaaagca
    27061 ggtcctgctg aacatgcaca gctcatcata taatctttat ttccaaatac aatctctcca
    27121 ttagttccta aatctataaa taaaacattt tcttcacttg accatatccc tgctgataat
    27181 actcctgctg ttatatctcc tcctacataa cttgcaacag atggagctaa gtacacatat
    27241 gcactgtcat ttacaaaaag accaacattt tcacccataa gttttggaga ttttaaaaat
    27301 ggtggtatgt aaggttcttg tcttaagaag tctgtataca cacccaagaa taaacttgtc
    27361 atagttgtat tcccggcagc cactaatgta actacatctt ccttatctat tccatttctt
    27421 tcatatattg tttttaatag tggatttata gtttcctcaa ctatagcttt atgaagtgtc
    27481 tctaatccat ttttcttagt tgaatatata attctattta taacatctgc tccatatttt
    27541 atctgtgcat ttccagaaga tgctttatct actacctctt ttgagtatag gtctactaaa
    27601 caaacaacta ctgaagttgt accaatatct attgcaactc cgtataagga attttcttta
    27661 tttccttgtt ctatatttat gattgtaagt ttcttttgtt tttgaacata tgttattgta
    27721 accttaaaat cactctttct aaatacagtt ggcatttttc taagtatatc caatctaaaa
    27781 tctatttcat tatatcctag gttatttcta acatatcttt ccaatctatc tacatcactt
    27841 atattatcat ctaaatttgg ttcttccatt tctatgtatt tcttttttat atttgtttta
    27901 aattgaaggt tatgttcttc aattattttt ttagctcttt caaaaatttc cctatcctct
    27961 tttttattac taccttctat cttcatacca tgcatagaag atgatacttt agaaggaact
    28021 tcaatttcta tatctgatat tacctttgta caacaagcta gtatataacc ttgctcccac
    28081 tcatcatctg ttatatgtct tgttttttct gtatcaactt ttccattcaa taattttact
    28141 ttacacttcc cacaagacac gtttccatta caaggagcat ctatgaatat atctgcattt
    28201 cttgcaacct ctagtaatat atccccctca ttacaataaa cctctttatt gtttggtgta
    28261 aaacttactt ttatcatgtt atccctccca atttgttcta tatatgataa aaggaaagta
    28321 tagctaaatt tgcgtgcact caaattttac tatactttcc ccaattataa taatatctta
    28381 atctttaatt attctaatcc agcctcgtat tctttatcac ttaataacgt atcaagttca
    28441 gccacatcag ctagttttac ttttaatatc cagttttcat atgggtcttc atttatacat
    28501 tctggctcat cttctaattt ttcattaact tccaatacct caccattaac aggagatatt
    28561 aaatcagaag ctactttaga agactcaact actccaaaat ctactccctt agttacagta
    28621 tcttctactt ctggtgtttc aacaaacaat atttctccta attgatcttg agcatagtct
    28681 gttataccta tatatacaac atctccatca attactttta cccactcatg atctttagag
    28741 tattttaatt ctggtaataa tttcatttcg atagaccccc aatattatat tattgattaa
    28801 attacttaaa tcatattaat attatatcat attattttaa attttccatc aattacatta
    28861 cactttccat agctaatgct ggatgacctt tttcttctaa gaaagctaat actccttcag
    28921 aatcgtcagc tatagtttca tcacaaacca tatcacagaa gttttctatt ccagtcattt
    28981 ctttaactgt agcatttaat ttatcagcta cataatcttt taattctttt ggcatccaaa
    29041 ctattctttc tggtccacct tctgcataag cgaatttttt agaagatatg aaatgtcttc
    29101 cgtgtcccat aaatcctgga gtttgaactc ctccacctgt catagaagca agttctccga
    29161 aagtcatacc aactggagta acacttgcaa attctctgtt aactacaaca aatccatttg
    29221 cttctggcat tataccacag atacattcga agcatccaca agaagtcatt gggtcttcta
    29281 gtatagagta taatgtaaca gattcaactg caccttgaga tatttggttt acagtttcat
    29341 ttactgaatt ccatacacct gttctatcat ctaagcactc gcctttttct attggttgac
    29401 aaggacctgt tgggtctagt tctttagtag ccttagcatc taaccagcta actgctccac
    29461 aaagaccaag tctttcagga gtaacaacac aaacgtgagc tggtgcaaat gattgacata
    29521 agttacaaga atagaaagtg tcaacacttt catcaactaa tgaagctaat ctttcatctc
    29581 tagcattgta cttagctatt gcttcacctt ttaattcaga aactttttca gcatctgtaa
    29641 ttatagttat ttcacactta tcaactactg attcaaattc atctaacatc ttagcatata
    29701 aaacttctcc tatatgctca agtctaaatc ctttatcaaa tgcatcttta gagattctta
    29761 cccaagccat atctctttgt ccaacgtgca ttacaccttc tatatagttt aagaagtagt
    29821 ggaaacgtct ttcaagaact ggctcgaaat cttcttgcat atttttacca gctattttaa
    29881 ctattacagc aagtggtaat cttaatacac catctgcatc aacttcatct atatttggtc
    29941 ctattatttc tatcttatgg tcttcaactt ctgttgcttc tttcttaaca acaagctccc
    30001 aagcttcagt tctgtttcca ccaaactcag caaacatatc gctctttcta attctctcac
    30061 cttcaaatgc tgctgcaaat gaaactggga taggtatttc agtaactttt atttttattc
    30121 ctctagcttc taatgaagta gctactatct tatcgtaatc tttttgagtt aataggttca
    30181 ttggaacttc aagaactgtt tggtcagtta taactgggaa tcctaaagct attgctccag
    30241 cacctgcaga tacaactaat tcacttaatg gtccaaatgc attaacaaat gcaggaactc
    30301 tattagctgt gtactctaat aatccgttta aatcaccagg agttaatcca ccgaatatta
    30361 atgctgctct tactgcaaca gatacaacgt gtataacaga agttacatca tatcctagag
    30421 gtataactct tagctcaaga cccattttta ctccagcttc tatagcttgg tctataactt
    30481 taccaactaa gaaagttagt aaacctttag attggtaatc ttttataact tttgctgctg
    30541 attctgcatc tggacactca ccaagaacaa ctgcaacacc aggtatatct cctgtaacta
    30601 atggtacacc aagtgatctg attatagggt cagttatatg acctgcacat ggctcactat
    30661 atggagcatc catagttgaa tattttaatg cttcaattac ttctgctgct aaagctgtag
    30721 ctaaaccagc attaaaagca tgttctagta aatgagttct atttattaaa gattttacta
    30781 cttctaaagc accttctaag tcccctaaag tgttcatctt ttgtcctgtt gcagcatata
    30841 tacaaggtaa tgaatatgct gtatcaggga aagcaacttt atgctctttt ccattctttt
    30901 ctatagcttc agctaacata gcttgagccg cacctaaagc ttgttctgac cctgtaaaga
    30961 ttatattata tagattcatt ctatttcccc ctttaatatt tacacctatt ttttattaac
    31021 tataccctaa aaaccctaga aagcaaatcc accttcattt aactctaaga aagagtctgc
    31081 atataaagat gccccgttga ttatgtcaca agattttaca gttttcatta attctgggtc
    31141 acatggattc attatagctg aactaaatcc attagccatt gccattgcta agaatgcact
    31201 atctaaaaca ggtctaacat gcttaggaca tccattagat acgttagata atcctcctgt
    31261 agttaaaagt cccatctcag tcatcatttt tatagcttct aaaacttcta cttgtttttc
    31321 ttgcatacct tttataacta agcataatgg gtcaaatagt atatcagttg gctccattcc
    31381 taacattaag cctttttcta atatttcttg gcagtaagcc atacgctcat cattatctct
    31441 tgggatacct tcttttgcac ataaacctat aaccattgct tcgtattcag ctgctatatc
    31501 tattaaatca aatcttgaac cagcatcagc agagtttatt attggttttg cattagttct
    31561 atcataaact tttagtccag cttcgatagc ttttttatta gctgtatcta atgctatagg
    31621 aacattgttg aactcagatt gaagtaattt gattccccat gtcattattt cttcgccatc
    31681 tctttcggca ggtcctatat taaaatctat atagtgtgct cctgcttcta attgctcttt
    31741 tgctcttttt aagattggag ctgggtctct ttctgctaat gcttttctta ttgaaggtga
    31801 tatacaatgt attctctcac ctataatcat aaatttttcc atttataatg tcccccttta
    31861 aatttaatat taatagttag ttaatatttt attagtttgt ttggcatgct ttttcttggt
    31921 atccttttaa gaacttaggt aattccatag attcctctgg tcctataact acattccatc
    31981 ctggtaagtt atcttctata tcacctttaa gtactgcaac ttttcctgga atgataaggt
    32041 ctttacaatt agttacttct tctaccttac tttctttaat gaaagcagag attgagtttc
    32101 caccaaattt accagcagcc caagatgtaa gaactgaata tccacctgca tctggtatta
    32161 ctaaccatac tggaactttt gatctttcta tatcaccagc aactatgaag taagttaatg
    32221 caaagtcaac agtaactaat actggagaat tttcatctgg gttgttgatt ggataaatct
    32281 ttggttcaac tctcattggt ctttgtgggt cagtgtatat gttttgtctt agtgcaaata
    32341 atggtaatgc cttagcataa ctaatatcat ctattactat tatagaaccg tattttatag
    32401 tgaatattga tgataaagca acttccatca tagggtttga attagataat ctatttgcaa
    32461 atactattga aggatatcca aatgttctat cttgctcttt taaagctgtt cttctaactt
    32521 gtatagcatt agtgtaagta tcttttatgt tttctcctgt tacatctaat actaattctt
    32581 tatatccagc ggcttgaatt aattcaactg tttcatataa ttcttctaag ctaccagctt
    32641 ttacacctaa tggtaaactt gctcctttaa ctacttctat catatctttg tagttctctt
    32701 tagttgctcc atataccatt ggtctagcat cttttaatac ttcaacagct tctttaacta
    32761 cttgtgcatc atcacaagct aaaatataag ctacttctaa tccactgcct tttattttat
    32821 ctattaattt taaatacgca tctttatctc cacaatactc taaaacagcc atttcaactt
    32881 tcatttgttc accaattctt acatagtcaa cttttttcat gttagctatt ttagcatcta
    32941 ctgcttcatc actcatacaa gtacagaatg aaactgcata tctatttcta cttactaatg
    33001 ttttttcatg tctaaataat actgtttctc cacctagttc atactcagat gcaccagcac
    33061 caacttttaa agctttcatt aaaggtgcag tagcctctga taattttgct atagcgtcat
    33121 cagacatatg tgggcattta cctacttcta cagctcctga agcaaccttc atagagaaag
    33181 ccatacaagt tgggaatcca caatccttac agtttttctt tggtgttaat ttaaatatat
    33241 ctaaagcttt taatgccatt attttttccc cctaacctta acaatttaat taagctaatg
    33301 cgttaaccaa ttcttttata gtttctattg attttggatg acgaagtata actgcgtttg
    33361 aaccacctac taaaacactt gctgcagttg aaacttccat tgctatagtt ctttcttctg
    33421 gacaacccca atctggctca tcttctattg gagctatagc ttctttaaca tgacctactt
    33481 caaaagctac tggtgttatg ataggcattt gtaatgtctt atcattttga ccaaatgctg
    33541 caagtctaat tctatccata gtagatgcaa cgtactcata tccataacca actgctgaac
    33601 atccaacatt cataactata ttttcacctt taacgcctag ttgagttaac aatacgttta
    33661 attgtttagc taggtttata tcaacagaag attcagctcc tactttatgt gcataagcca
    33721 taccagctga tgctcctact cctttgtagt tatcttctac tgctgacata aataagcagt
    33781 tatgtccatc caatgtttga gctaattttt caaataattt accatctttt tcatgatttc
    33841 ctgaaccagc tacaactaaa ggtaatttta ttgcttcaat tactgcctta gctacatcag
    33901 cacattcatc aactgactta tctaatccat ttgggtcaga accatcaaat tttaaacaaa
    33961 taaaatctgc ttgtgtatta gcttcaacat atttagccca ctctactgga caattagcta
    34021 catctttgta taattcctta tatgaatcag tccagctttc aggataaacg tctgatattt
    34081 gtatccctat ttttggagaa ttacctactt ctccatcaaa actataaaaa ggtaatacat
    34141 tttccccacc taatttaatt gctttttccc ctattcctac ttcaacttct gatatttttc
    34201 cagaatattt ttgagtagac attttaaatg ccatattttt ttccccctta agcctatttt
    34261 aattctaatt tagcaaaaat ttctttcata gccactttag attttgaatc ttcaggtaaa
    34321 ttaactaaag gaatacctgt agaatcatat tcatatatca attcatccat aggtacaaca
    34381 ccgattagct ctaggttatg cttttcaatt tcttctttaa caccatcatt cataactcca
    34441 tttggaactt tatttacaat caaaagtatt cttccaacac ttaactttag ttcctcagct
    34501 aaatctctta ttctagcaac agcttgtatg ctacgtcttg agcaatcact aaccaataaa
    34561 agtgtatcaa catgtctagt gacttttcta cttagatgtt ccataccagc ttcgttgtcc
    34621 atgactaagt atttgtaatg accagatatt ttgtttactt gttctctaag tatcccattt
    34681 acaaaacagt aacatccttc accttctgac ctacccatta ctaataagtc atatccttcg
    34741 ccttcttcga ttatagaatt taatctaaat tgaagatatt gtgcctttgt cataccacca
    34801 gggaatgcat tgcctaactt ttctctttga tttacttctt ctcttatttc tcctattgtt
    34861 gcttcaactt cgatacctaa tacttcattt atgttagcat tggcatcagc atctacaact
    34921 aatactggtc cctttttgtc cttaaccaaa taatcaatca aaagccctgt gagacttgtt
    34981 ttaccagttc caccttttcc tgcaacagct atattgtatc ccattttaag acttccccct
    35041 taaatctagc cacagagcct tatgtactct gtctgtctat tataatttag gtacagaatg
    35101 aacacattct ccatgtacat catgaagtgc ttccattagc ccttcagata aacttggatg
    35161 tggatgtatt gcatccccta cttgttctac tgttaatcct agatgaacag caagtgacaa
    35221 ctctgtcaat aaatctgtag catgaggtcc tactactgct gcacctatta tcttatcagt
    35281 ttctttgtca gctataactt ttacaaatcc ttggaaatgt cctatagctt gtgcttttcc
    35341 aagacctcta aaatcaaatt gacctacatt gtattctaca ccttcagctt caagttgctt
    35401 ttcagtctta ccaacaccag caacttcagg ttcagtataa acacatcttg gaattgctct
    35461 ataatctact accttagtct tacctaaagc attttcaact gctacgatac cttctttaga
    35521 agcaacatgt gctaggaaag gagtatctat tatatcgcct attgcgtata taccttctac
    35581 attagtttca agatgttcat taactactac ttttcctctt tccatttcaa ttcctatatc
    35641 ttctactcca gaattgtcaa ggttaggtct tctaccaaca catactaatg catattgtgc
    35701 ttctataacc tttccattag aaagagttgc aacagcctta ccatcaacta cttcacaagt
    35761 ttgtactcca atacctgtaa taaccttaat tttatctttc ttaaattgtc taagtagttg
    35821 tttagctaca tctttgtctt catttaatag tatttggtca accatctcaa ctatagttac
    35881 ttctgttcct aaggctctaa agaactgccc tatctcacat cctataactc caccacctac
    35941 tattaacata gactcaggta tctcttcaag tccaagaact tcatcactag ttattacaac
    36001 ttttccatca tatgggaaca ttcttggtac aactggaaca gaaccatttg ctagtattat
    36061 cttatctgct tttatagttt ctactgttcc atcatcttta gttacttcta tagtgttttt
    36121 atcaattaat tttccaaaac cattaactaa gtttactcct cttttttcaa ataagaactc
    36181 tataccactt attaattggt ttacaacttt attttttctt tccattatgg cagtgaagtt
    36241 tggcttaact gtaccatcta tttctatacc aaaatccttt gcttctttta cagtattcaa
    36301 tactcctgaa gaggcaagaa gtgctttagt tggtatacat cctgcattta agcaagttcc
    36361 tccaactctt cttttttcaa caactgttac atctgcacca agcatagaag cttttatagc
    36421 tgctacatat cctcctggtc caccacctac tactactatc ttcatcttta attcccccaa
    36481 acctaatata atctacaatc ttgcaatact ataaacctgc ggcatccagt atagcaggta
    36541 tattctcttc tgccccaatt gccattatat gaacaccatc acataaatct tcttctttta
    36601 attgtttgat aagttcccct gccattttta ttccttcact tacccagttt tcttttccag
    36661 ctgctcttaa tctttcgatt tgttcatctg gaacaaatat tcctggtaca tttgcagtca
    36721 taaatttagc cattcctggt gattttaaag gtactattcc tgctaatacc ttgcaatcca
    36781 tatcccttgt taattctcta aactttctca ttgtatttat gtcataaagt gcttgtgttt
    36841 ggaaaaattt agcccctgct tttattttct ttttcatttt taataattga acttctattg
    36901 gagaatattc tggagttact gatgctccta gataaaaatc tggagaacct tttaacttat
    36961 taccagccat gtccgtacct gccattaaag tctcagcagt ttgaagtatc cccacagaat
    37021 ctaaatcaaa cactccctta gcttgtggat ggtctcctac gctagtatgg tctcctgtta
    37081 gtgccaacag attgtttatc ccaaatacac ctgctgacaa catttctcct tgtatagcta
    37141 ttctatttct atctctccct gttatttgaa taactggctc taatccagca tcttttaata
    37201 atttacatgt agcaagagaa gttgctctca taactgccga ttgaaagtct gttacatttg
    37261 ctgcatgaac tcttccaact aacggctttg cacattctat taaatgtgaa aggtcagtcc
    37321 cttttggagg agccatttca gtagtaactg caaattttcc actttctaat gtttctctta
    37381 ataagctcat ctctaatccc ccttttaacc ttctaaaaaa aacttttatg aatttgctgc
    37441 tgcttctttc tttttctttg cacttatact tcttggatta ttttgcttag aatagtcttt
    37501 tggtggtctt atttctgcta agttatctaa ttgtcctata gcttctagtc tttcatatat
    37561 ctttatccaa gcacaatcat tctctgagtt tacttcacac ttaccatttt tagctccacc
    37621 acaagcccca ttcataagac ctttagcaca catagttact ggacatatcc cacctgtcca
    37681 accaagttca cagtctccac aagccttaca ggcttcttca tattctccaa ctctttgtac
    37741 ttcccctata aacaaagtat tgttggctgg ataaactggc ttatctttta aattcttaac
    37801 tattgtctgt gtaccatctc cacatgctaa agataaaact gcatcagctt ccttagtctc
    37861 ttcttttaga gcctttaaat cctttttaga ctttaaaagg ttacaagcag ggtcaagcat
    37921 tacatatcct aagatttttt tgccttcacc ttcaagagtt tccttcattt ttaaaacttc
    37981 ttcttcccca ccacttttac aagttgctgc acattgatta caaccaacta aaaccagctt
    38041 gtcaaaatct tttaagtacc ctagcacttc ttctaatggt ttattttcag aaattatcat
    38101 atctacttcc cccctaaacc ttccacatat atatatctat ttattgtttt gtaatttaca
    38161 agccttaact acatgttttg caagtataga tgttgtaact gaaccaaccc ccgctggaac
    38221 tggagttatc attgatactt tgtctaaaac tgcatttgta tcaacatctc cacataaatt
    38281 tccttcttca tcaacattta taccaacgtc tataactacc gctccatctt taacaaaact
    38341 ttcatcaacc atcttagctc taccaatagc tgctattagc acgtctgcct ctgctgctac
    38401 acctgataga tttttagttt ttgaatgaca tattgtaaca gttgcgtgtt cacttaataa
    38461 aagcattgat actggctttc caactaccat tgatcttccg agaactgtta ccttacttcc
    38521 ttttaaatca acattatagt gttttaatat ctcaactact gctgtaggtg tacatggtgg
    38581 aaatccactt ttatcccctt ccattacctt agcagagttt attggactaa aacaatctac
    38641 gtctttttcc ggtgcaataa catattttat aacttcttca tttaagtgtt ttggaagagg
    38701 tctaaaacat aatataccat taacattttt gtcatcatta actctcttta atacatcaat
    38761 atattcctct tgtgttatat cctcagctaa ctctaacact tctgttgtta tacctatgtt
    38821 ttgacatctc tttagtgctc ctctttcata agataaatca tcacttcttg ccccaactct
    38881 aactattgtt agtttaggat ttataccttc tttaactagt aaatcgactt cttttattaa
    38941 ttcttcacta attttatcag ctacaggttt tccttttata atttgtcctt tagttgacat
    39001 tccttccata cattcacaac tcccctacaa gcaaacttaa attaatttat tctatatacc
    39061 acatattaat aacatagtat ctactttcgt catttaaaaa ttattttcca agagcttttt
    39121 caactttggc ataaacttca tcacaaattt ttacaccatc ttcaactaac ttatctactt
    39181 ctgtttttac cttattaaca tattctttat cttgtataga atttatattt ataactacat
    39241 ttaattgtcc accaagtata gcagctctta aacactgaac tcctacacca acatcactta
    39301 tagcaagtct tgaaccttta tcaactaaat cttcatgtaa cttaatagct tcatagcaaa
    39361 ctcttactat gtttaatggt acttcacaag caacttttaa tgccttttcc attgtttctg
    39421 cttttattct tttttcttct tctgtttctt taggaagccc gtaagctttt gataatggta
    39481 agaaacattc tgcatcatca tctatcattt ttaataaatc tttttctaac tttcctgcct
    39541 tacttaatat ctcttttaca ctttcttcat actcagcata cttcttcttc cctattgtaa
    39601 ggttacatac catactacct aaagccatac ctattgcacc tactagtgca gcagctcccc
    39661 caccacctgg tactgcttct ttggaagata gtacttctac aaaatcaaca caagttttat
    39721 ctgctatttt catgataatc ctccttgaaa ggatgtagga aaatatctca aattgttcga
    39781 gatattttac gaactatttt aagatatctc ctactcttta tttataaatt aatttcctta
    39841 gaataatcca gctattactc cattttcatc aacatctatt ttttctgctg ctggaacttt
    39901 tggtaatcct ggcatcttca ttatttctcc agtaagtgca actataaatc cagctcctgc
    39961 tgaaattgtt gcttgtctta cagttattct aaatcctgtt ggtctaccta atttagtttg
    40021 gtcatcagtt aaagaatatt gagtcttagc catacatact ggaactttag taaatccaag
    40081 tttttctaag ttagctattt ccttatcagc ttcaggagta taatctacac catctgctcc
    40141 ataaatctta gtagctatag catttatctt gtcttttata gataaatcat cttcatagca
    40201 gaatctaaag ttattttctt cttcatccaa taatcttaaa acttctttag ctactgcaat
    40261 tccaccttct ccaccttttg cccatacttc agaaagagca acattaacac ctaattcctt
    40321 acacttgtct tcaacaagtt taagttcagc ttcagtatca agtgggaatc tgttgattgc
    40381 aacaactgct ggtaatccat atacttgagt tatgttttca acatgtttta ataagtttgg
    40441 aagtcctttt tcaagagctt ctaggttttc gttatttaag tctgctttag caactccacc
    40501 attgtatttt aatgctctta cagtagcaac tattataaca gcatctggtt ttaagtttgc
    40561 cattctacat tttatatcta agaatttttc tgctccaagg tcagcaccga aaccagcctc
    40621 agttattaca taatctgcaa agtgcatagc cattcttgta gctataacag agttacatcc
    40681 atgagctata tttgcgaatg gtccaccgtg tacaaatgat ggtgttcctt caagagtttg
    40741 aactaggttt ggttttaaag catcttttaa taatgcagcc atagcaccat tagcttttaa
    40801 ttgtctagct gttacaggtt caccttcgta gctgtatcca actattatgt ttcctaatct
    40861 ttcttttaaa tcagatatat cacttgccaa acagaacgct gccattattt cagaagcaac
    40921 agttatatcg aatccatctt gtctaactgc tccatcacct tttttaccca taccatcaac
    40981 gatatttcta agttgtctat cgttcatgtc tacacatctt ctccaagtta ttttcttagg
    41041 gtctattcta agtgcatttc cttggtgaat atggttatca agcatagcag ctaaaagatt
    41101 gttagcagct cctatagcgt gaaaatctcc tgtgaagtgt aagtttatat cttccatagg
    41161 aacaacttgt gcatatcccc caccagctgc tccaccttta acaccaaata ctggtcctag
    41221 agatggttct cttaaagcaa ctaatacatt tttgtctagt ttagcaaatg catcagcaac
    41281 acctatagta gtagtagttt ttccttcacc tgctggagtt gggtttatag ctgtagttag
    41341 tattaactta gcttttttac cagtctctct ttttagtaga ttgtagtcaa cttttgcttt
    41401 gtatttacca taaagttcta catcatcttc acctagtcct aatttttttg caacctctct
    41461 aatatcttga ggcttagctt cttgagctat ttcaatgtca gatttaaatc ccataactga
    41521 atctcctccc acaacctaaa tagatttaaa atataatttt tgtaaaaatt gtattaatat
    41581 gtaaaaatta tattttataa gataattata catgtaaaat tacttaaaaa ctagctacta
    41641 agctattaaa atattcaaac ttaatagcta gttatttatc taattactta cttattacct
    41701 atctattgcc tatgtctaac ctttaaccaa cttaaaatcc caaatcaaaa tttctatcta
    41761 ttttatttat ccttaagtga cattaattta tcttttattg ctttaatctg ttctttcgtt
    41821 gtttcactag aatcatatgg agattgattg gctctatcag aatcaataac atcttggtta
    41881 taataaataa atcctaaaga ttctccatct tctaagtttt ggattataaa ttcttcatct
    41941 tccttatttc taattttatt tcctactaca aatactttat ttacacctat atcatgtcca
    42001 agtttcttaa cttttctata agtctgtaga cttctctctc ctggttctac aactactata
    42061 aaagcatcta caccttgggc tgttcctctt cctaagtgtt caattcctgc ttccatatcc
    42121 ataacgacta catctttatt ttgtagtatt aaatgtgagc agagtctctt caaaagaaca
    42181 tgctctggac atacacatcc agtaccacca gaatctacgg ttcccaatgt aagtaatctt
    42241 actccattgt attctttaca gaaattttca gggatatcgt ctactttagg attcatctta
    42301 aacatttttc caaatgaacc tacagaagca gctgttctat ctgaaactaa ttttttcatt
    42361 tctgatatag gtactattga ttcatatact tcttttggaa aacctagtgc taaagctaaa
    42421 ttagcatcag ggtcggcatc aacagcaaca actctgtatc cgtcttcagc aaacatccta
    42481 gagagcattg aagaaaaagt cgttttacct actccacctt tacctgttat tgctatcttc
    42541 ataatcccta ccacctttta ttactatttg ctttttagta gttaatttta cagttaaata
    42601 ttttttatac tctatatttt tatacactaa aaataaacta cagctagtcc ttacaggaac
    42661 caattaaatt taccctacta gcttttcaaa gcagcatgta tagttttatt attctttaat
    42721 attgtttata ttttatttat tcagtatatt cattatattt tgatgttctt tactttaata
    42781 tttgacttta ttcaacttta ctcaaccaga aacttcttat aaaaacgttt attctataac
    42841 ttcactattt tttaagcttc agccttttct gccatttttt cttcaactaa tgcttcaaag
    42901 tgaacacgtt ttttctctat atcttctatt attgtagctg ctaactcttt tggatttgta
    42961 tttacagtaa atgtagctcc aactttatct tttaattcac tagttaatat atccactgct
    43021 cttgaagaac cagctattgg aggcattatt cctaaataag tgtctatacc agaagctaca
    43081 acatagcatc ctatagcaac tgctttttct gacatccact ctggagctat acctacaact
    43141 ggaaggtcac acatatccat atctaagtaa ttagctgctg ctccaaccaa atctagtata
    43201 cgacttatat caacacaaga acccatatgt agtactggtg ggattcctac taatttacag
    43261 acagttgcaa gacctttacc tgcatatttt tcagccgcat cagattccat taaaccaaac
    43321 ttagctgctg ctgaagctcc acaacctgta gtaactacta ttatgtcgtt tttgattaat
    43381 tctttcatta ttgttacgtg agcctcattt gaaactcctt tagcattgtt acatccaact
    43441 acaccagctg ctcctcttaa tactccagct tttagacagt ctgttaatgg cttaactgtt
    43501 cctgctgggt ctatatgaga gtttacaact ctgtctaatt gatttactac tgcttctaca
    43561 ctatacccaa ctgttgcgcc tgattttaat tcaggtataa gtacttttga tttatctcta
    43621 tttttaaagt ttaaaatagc ttctttaact attgctttag catcatcaag tgcttgttct
    43681 tctctaaatt caatataagt tgaacctgtt atcttagctt ttggagaagt tgttacaaat
    43741 ttagtatggt aacaatctgc aactctagct aatgcaggga atatacattg aacgtcaact
    43801 attacagctt caactgctcc agttattatt gcaagttctt gttgatggaa gtctcctgct
    43861 atttttacac catgtctcat tgtaatctca ttacctgtac aacacatacc tgctaagttt
    43921 attccatcag caccaacttc tttagctaaa gctactaagt ctggctcttc tgatgctaaa
    43981 actatcattt ctgataatgc tggctcatgt ccatgtaata ttatgttaac tttattttct
    44041 tctaatactg ctaaattcgc ctctgttctt cttggcactg gagttccaaa taagatatcg
    44101 cttagacgag tacctatcat agaaccaccc caaccatcag ccatagaagt tctaagactc
    44161 atgtgtatta aactatctat atcaccagta catcctatat gagtagagtg cattattgtt
    44221 gcaatttctc tatctatagc tcttggctct atagcgtatt ctttccatat tttttgtctt
    44281 ggttctggtg cattttttat aaatcttaat gtcccaaaag gttttccaaa ttccattaat
    44341 gcaatttctg ccacttcatg tgctacatca tagatatctc taccttctgt ctctacatcc
    44401 cattctttag ctaaagtaat taacttagct tcgtctctta ttttatagtt tccatttgga
    44461 tcagctaatg ctaatgtatg tgctatatct ctagcatggt ctgaatgggc agctgtccca
    44521 ccagcaacca ttcttgcaaa gtttctacct actatagtat gctcatctgc tccacataac
    44581 ccccttggag tcttagggct tattctacat ggtcccattc cacatattct acagcaaaca
    44641 ccttgaagac caaaaccaca ttgtgcctta aagccttctt ttctatcata cattgtttct
    44701 acgccttctt ctctagcttt agctatcatc ttctggctgt ttaaatcaat tgttaacatt
    44761 ttttcatcca tattcctatc cccttttttt gatttttaaa atcccccagg tgactgactt
    44821 catgtcataa aataataaaa taaatgcttt ctaagttgat tatatactaa ttttcagtgc
    44881 tttgctttag atttaaatat ttttttaaca aaattagata atacataaaa attttatttt
    44941 ctacacttaa tttaagttga ttttatcgct tgtttttggc tatttgttaa tatctaaacc
    45001 tacttttttg atacttcagt ttaattaaat tatgttttga tttttttaaa tcaaatttga
    45061 aatttttcta gtcattttta tattattgca gattgtttgt gtatttatta tctttcacta
    45121 ctgtttggac ttattacaga tttttactcc ctaaacttaa ttagtaaaaa tttcttagaa
    45181 tagcattttt tggactaatt tttttgaatt tttttatttt tcctacttta atattaatta
    45241 tagcttcaaa ttgaacattt gtatatattc atttgaagct ataattattt tttatataaa
    45301 acttttttaa tacagcatta atttagacat tttgactatt ttttctactt taattcattt
    45361 atttcaagcg atttatccta tttcatattt ttagctacaa tagccccata tgcaatagaa
    45421 tataatttag attcatgtga atcagctctt gacactaaaa ctataggagc ttttgcaccc
    45481 ataattatac ctgctgattt agagtctgcc atatatgtaa aggctttccc tattccatta
    45541 ccaacctcta ttgttggaac caatatgata tctacatctc cagatacttc acttttaaac
    45601 ccttttatct cactagcttc ttttgaaaca gctaaatcaa aagccagagg accttctaca
    45661 attacatttt caccaaattc tccttcttta caagcttttg ctaacatatc tgcatctaca
    45721 gttgcttgca tcttaggatt tactttctct ttagctgcca aacatgcaac ttttacagtt
    45781 tccattccta aagcttttgc agcttttata gaatttttta atatctttgc cttttgttca
    45841 taatcaggag ctatattcat acctccatct gtagttataa gtaatttatg gtatttttct
    45901 aactcatata ccataacatg acttaataaa ctatcagttc taagaccata gtctttattt
    45961 aacacttctt ttaatatgac agatgtatct aataatcctt tcattacaaa gtcggcttct
    46021 ttacttgata ctaatttaac tgctatttct gcacactctt tgatatcatc cttatccact
    46081 attttgatac cacttaaatc aaatcctatt tcttttgata tttctcttat tttgccttca
    46141 tttccaacca atataggagt aattatattt ctttctacag catcctttat tgccattaaa
    46201 acttctttat catgagctgc tgctacagag agtacaattt tctctcctcc cttaagttgt
    46261 tctaaaatat catctaattt ttttatcaaa agtaacccct cccttatata tatttaacta
    46321 aataatacca tatttgctat accttttctc aatttatttt ttatgttata aagaatttat
    46381 ataactaaaa gacagtttaa tattttattc tgggatttca tcaataactc ttaaaagctt
    46441 tgcaggaaca ccacctacaa tagtattttc tgcaacattt tttgttacaa ctgctccagc
    46501 agcgataatt gcattatctc caatagtaac tcctggaact acagttacat tagcaccaat
    46561 ccatacattt tttcctattg tgattggaga aggataagtt gtaccacgtt tctctggtgc
    46621 aataccatgg ttaagtgtag ccaataccac attatgccca atttgcgtat tatctccaat
    46681 ctcaatcccc ccctggtctt gaaaatggca actgctattt ataaaaacat tttttcctat
    46741 tgtgatgttt tttccacaat ctgtataaaa tggtggaaac ataaaaaatg attcatctac
    46801 cttttttcca attaactcag aaaataaact acggacttct tctggttcat gataagaaga
    46861 atttaactta cttgtgattt tcattgcctc attactcaac ttaaccataa attcatgtat
    46921 ttctgattta ctagaaacag gttttctttg attgatatgt gttaaaaatt cattgatatt
    46981 cattttatac atcctttcaa tatgtgcttt aatttatttg tacattctaa ataatatttt
    47041 aataaaaatt aatttaattt atttttatta aaatatcatt gcttctttta gtgtaatata
    47101 caattatatc tatatcaaat atctatatta aatacttaac tatacttaaa aagcatttaa
    47161 attgatataa ttatataata aataagttaa tattgaggag ggataattat ggaaataaga
    47221 gtattaagat attttttagc aattgcaaga gaagaaagta tatctggtgc ggcaaccttt
    47281 ttacatataa cacaaccaac actttctaga caaattatgg aacttgaaga agagttggga
    47341 gttaaattat tggttcgagg aaatagaaaa atcaccttaa caaatgaagg taggctttta
    47401 cataaaagag cagaagaaat tatatcatta gttgataagg ttgaattaga atttgacaat
    47461 cccaatgaga ttattagtgg tgatatatat ataggaagtg gtgaaactga agctatgcga
    47521 cttatagcga gaactgccca tcattttcat caaaaatacc ccaatgtaag atatcacctt
    47581 tttagtggga atgctgatga tgtgactgaa aaattagaca agggactgct tgattttggt
    47641 attttaattg aacccgcaaa tatacagaag tatgattatg cacaaattcc tgctactgat
    47701 gtatggggtt tactaatgcg taaagatagt gcccttgcat cacaaagcac aataaatcca
    47761 aaagatttat gcaatatacc tcttattatt tcaagacaga cacttgttga taaagcaatt
    47821 tctaaatggc ttcaaggcag taatgaaaaa ctaaacatta ttgcaacata caatttagtt
    47881 tataatgctt ctcttttggt agaagaaggt ctgggctacg ctctgtgttt agatagactc
    47941 gtcaatacta cagaaaacag taatctttgt tttagacctc tatctcctcc tttagaagct
    48001 aaattaaata ttatatggaa aaaacatcaa atattttcaa aggcagcaga aaaattttta
    48061 cttcaaatac aaaaagattt ttcttctatc atgttggata catctaagtt ggatacaccc
    48121 aaagaaaaat aaatcataat aaaaagtgag agtgtctcaa aatgaacttt gcactgtata
    48181 aggcactctt ttttatacaa agtaaaatat atgttcatca tttcagcact aaaaaagagg
    48241 cttatctcta ttttgagata gccccactta accaataaaa ttaaatacaa cttaacaata
    48301 tccttactta tttattccaa gttctcttag acaagcaata gtaatttcat cttgtggatt
    48361 taattcataa gctctttcta tatagtaagt tgcatcatca atatcaccat tatttaaata
    48421 agccattcct aaattgcaaa gtatttctgg gtcttccttt atcttagccg cttgttcaaa
    48481 atactctatt gctttatcta aattattctt ataagcctca caaagcccca attccactat
    48541 agtatccact tgattaggct ttattatcaa tatcttctca agatacatct tagcctgctc
    48601 tatttcgtcc atacccttat atccaagtgc tatcataaac agcaagttcc accaatccat
    48661 atgttcttct tctaatggaa gtaacttctc taatccttcc ttaaacttac cttggaatac
    48721 aagtgtatat ccttcttcat attgaacttt aaagtccatc ttgcccagat tctcttgtac
    48781 ctcagctact aaatcagcat ctaaccctag ccttaacgct tcttcccaag tcagcttagt
    48841 ctttaaatat tgaccttgat tataataatg gtagcctaag tgataataac ctaatgcaaa
    48901 attctcatca acatcaatta ccttttcaag cttagccatg gcttcaagta agaatgcatt
    48961 cattgcctta tcatccatat ctttttgata ctgtttagct atctcttggc aaacaatcgc
    49021 atagttatac attgcatcta aatcatctgg atacattgtt ataaatgctt ttatatatat
    49081 taaagaatct gtatgttcac caatctcaaa gtattttctc gacatatatc ccatatacga
    49141 tttcaaatcc aaatcaatat cttttgataa agcatttaaa aacttctcat actctgcatt
    49201 gtttttaaac ttactatcta ttccaattat atatatcatt gcatctgcta tagacattga
    49261 atttaactta tcttgagcag tcttttcttt tatccctttt actaatacct cattttttat
    49321 aggtacatct aatccacctt ttggcacttc atagcttttt aatttaaact ctccaccatg
    49381 ttttatagtt ataaaagcta attcttctgc tttttttagc aaatattttt ctatcttaaa
    49441 atccatttta tcctcctaaa tacttaaatc tctactttat gagttttaga tttctcaaat
    49501 atttttttat catcatactc aaataagact acattttcta cttctcttat ttctgtattt
    49561 atatcatttt ttaaatccac aacattaaat ctaaatggct caaaatgaac atattttatt
    49621 atatgtttag ctggtttatc aacaaaacta ggtaaatatg ttgataagtt atcattatct
    49681 tgtaaaaata catggcatct attcttaaaa tcatccacat ctagcttatt aaaaaactgt
    49741 ggtatatttg atgttttacc cagtgatata tagtcatatt ttaatatatc gttgaataca
    49801 tcattatcta tgttgatttt ttcattatag aaatccatca atattttata taactgattc
    49861 tttccttgtg ccaaatcaaa gtagccattt tcatcaaaat acttggcaaa aacctcaaag
    49921 aatttaaaag ggctttgttt ataaaatctg cctataatat atctcataga taacacaaag
    49981 tttttagaat tgtagtatct ctccagtata tcttctatat cctttagctt caaagtttct
    50041 tcatagctta tataattatt gtataaaaac tcatatggag cataatcctt atatttaaaa
    50101 ccatgctcat ctgcaacttt tctcatacct gtccctttaa tcatctttaa aaagcctaat
    50161 tgcagatgct ctatacctag attaaataca tcattaaaag aattttcaaa gctcttataa
    50221 tcttcataag gcagtcctgc aattaagtct aagtgctgat gtatatttct ataagatgct
    50281 acagtttgta caacatgaga caacttttta aaatcatccc ttctgcctac tgcatcaagt
    50341 gttttttcat tcgttgactg aacccctatt tcaaattgaa aaagaccttc tttacaatca
    50401 gccaaaaact caagcatctt atcatctatc aaatacgctg taacttcaaa atgataagtt
    50461 gtatatccat tatcattttt cataaggaaa tccatgattt ccatagccac ttttctattt
    50521 gcattgaatg tcctatctat aaactttatc tgtgatactc ttgcatctat taaagctttt
    50581 aaatcactct ttatcctgtc taaactaaaa taccttagac ctggaatagt agatgataaa
    50641 cagtactggc agttaaaagg gcaacctctt gatgattcat aatacactat tctattttca
    50701 tattcttttg gattcaagtt ttcataagga ctaggaatct catccaaatc ttgaagtaat
    50761 tccataggct tattcactat tatctcattg ccttgtctat atacaagtcc atttacatca
    50821 tttatttcca tctttccttg caagtgaagt actaagtctc taaaaattaa ttctccctct
    50881 ccataaagta tataatccac aaaatcatac tttttcattg cctcataact atcataactc
    50941 acttccggtc cgcccaaagc tattttagta ttaggtctaa ttttttttag attatcacaa
    51001 agtttaacta tatctcccac attccagata tatgttgaga ataatattat atcatattca
    51061 tttttatata tatcctttaa aatatagtcc aaatcgttgt ttatcgtgta ttctttcata
    51121 ttaacttcta tcaaatctct tacaaattct tttagatatc ttatagccaa atttgtatga
    51181 ataaacttgg aatttaatgt tgttaataaa attttcaaat atttctcacc tctttttaag
    51241 attatactgt ctttttgtac cccttatagg ttaaaatagt atatgtaaag tctaaataat
    51301 atctatataa ttaatttatt aatttcaagt aatgtgagga aaggaagttt tttatggaat
    51361 taattgaaaa agtatctatc aactctttat caaaaagaga tttactactt attataaagt
    51421 ctcttgaata cactaatgaa aatactcaaa ttagtgattt cattgacctt aggaataata
    51481 tagtaaagga attatgtttt ttaactgaca ctaaggaaaa agatttttta gattatctag
    51541 aaaaaaatag cacactctaa taacctaaac ctttttaaac tttaatatat aaatacctga
    51601 tttagaattt atttttatgc ttaatatatt atcattaaag gttttcgaca taactgttat
    51661 ttgattaaat atagggtcta ctatagtatt accttcttca agtcttataa gacttcttgg
    51721 gtctatgctt ttattatatg ccttaactcc aattttatat tttctcaatt taacaacata
    51781 ttcggacata gaaaaaataa aatctatatt atcttcattt aatttactat cttcacccaa
    51841 aatggataat atagattttt ttatgctatt aattccttca ttttctacag ttctatcttc
    51901 catatataca tcatatagaa catttaaaac atttaataaa atactttctt catcataatc
    51961 ttcagatttc aaatcaatgt acttatcaat taattgtatt gctttaatcc ttgccatctg
    52021 aaattttaca acatctgatt tgtctaattc tatagaaaat cctattatct tgtctttaat
    52081 actctgtagt aattcgacat actctatttt actattattt ataagattgt gcataatgga
    52141 attatacact acagaaccta ataaataatc aaataaaagt tcttcttttt taaaataaat
    52201 aacatacttt tttattagtt taataacctc atcttcactt ttttgaatat tagtatttga
    52261 taaaattagt ggtaataaaa tatttaaaaa attgatattt cctatttttt ctccataaaa
    52321 tctatagtaa ataagttcat ctctcagtct attttcgtct atatacacac atctttgcgt
    52381 tttatcatct attaaggatt ttgtatttat tatagttaaa tctttaagag ccctacttgc
    52441 actactaaaa gaagatgtgt agactttttt tagtaattcg tcattcataa atatatcctt
    52501 tctgaaaaat tgaatgtaaa taaattgtta ttaaaaaaaa agagacagcc cgtttaagaa
    52561 gctgtcatat atagggggat agtagtgtac aaaaatcatt gtaatctact atctatatat
    52621 tattatacga tactactttt ttatatgtaa agcatcagtt ttcgacatcc ctatatttta
    52681 cagttataca aattgcgtac taagttcaat tttattcttt ttatttcaac attttatcat
    52741 gctacattct ttcaggagcg tgcattccca acaatttcag agaattttct aaagtttgtt
    52801 ttgttgctaa aactaatgca agtcttgctt ttcttatttc caaattttct actaaaattg
    52861 gattgtcatg ataaaattta ttaaacgctt gagctaaatc tagcataaat ctagtcacta
    52921 tatgtggctc atttttcttt agagcaagta aaatattctt attgaatgat tctataactc
    52981 taagaacttc tgcactatct tcatcagcta atagactata atctatatca gaagtcactt
    53041 ctacttctgc ttttcttaaa actgcacagc atctagcatg tgtatactga acatatggtc
    53101 cagtctcacc atcaaaacta agcgttcttt cccaagagaa ggtatagtct ttaattctac
    53161 tattagataa ctcttggaat actactgccc caacacctac ttgcttagat atttcatcca
    53221 catttttagc atttgggttt ttagctagta taatttcctt agttttatct atagcttgat
    53281 ttaaagcatc ttctaaaaat actactcttc cttttctagt cgacatagta ccttcttcaa
    53341 gtgcaaccat accaaatcca acatgaatta aatcttttgc ccaatcatat cccataagct
    53401 caattacctt aaaccattgt tggaaatgta agttttgttg agaaccaact acatatatac
    53461 acttgtcaaa atcataagtt tcttttctat atattgcagc agctaaatct cttgtcatat
    53521 ataacgttga accatcattc ttagtaataa gtgctggtgg cattttatac tcttctaaat
    53581 caacaattct tgctccttta gactctttta aaagattttt ctcttctaat agttcgataa
    53641 ctctgttcat tttatcagaa taaaaactct ctcctgctaa agaatcaaat tctatatcta
    53701 aaagtttata aactctgtta aactctttta aactctcatt tctaaaccat tgccataatt
    53761 cttgtgcttc ttcgtcacca ttttctaatt tattaaacca tgctcttgct tcatcttcca
    53821 tttctgggtg ttgttcagct tcatcatgga atcttacgta taattttagc aattctggaa
    53881 ttggattaga ctctactact tctttttctc cccacttttt aaaggccact attaacttac
    53941 caaactgagt tccatagtca cctaaatgat ttattcttat agtcttgtat ccttgcgaat
    54001 catatatctt atataaagca ttacctataa ctgtagttct tatgtgccct atatggaaag
    54061 gttttgctat atttggagaa gaatattcaa ctattacagt tttatctttt ccaaaatcac
    54121 tatgtccgta attttctttt tcgtctaaaa cttttttaat tacagtttct gctaattgag
    54181 atttatttac aaagaaattt acatatccgc ctaattgtat tacttttgtt atctctccac
    54241 ttggttctat actttccgcc aattcacttg ctatcatgtt tggagctttt ctaaacactt
    54301 tggctaattt aaagcatgga aaagcatagt cccccatatc cttatttggt ggaacttcta
    54361 taagtgcctc tatctcttct ttcgataaat cttctatttt ttctttaagg caatttgata
    54421 ttgccacctt aaaatcttgc attctgttgc tcctctctac attgttcctg gtttatattg
    54481 tgcttatctc tttatgttaa atcaaatttc gtgttttttc aagtatttca ttacagtgta
    54541 aaacacttta gtaattatgt tttctgtata tattaaaaat actataattg cagtttttaa
    54601 tcacactatt attgattttt tataagactt ttttctattt tattgtttct tgtactatcc
    54661 agttgacttt atatactttt tttaatcttt tatctatttt catacgtcaa tgctaatttt
    54721 atatactttt cttttaatct tttattaatt ttcatacatc aatgttaact ttatatacgt
    54781 ttttttaatc ttttatctat tttcatacat caatgtcagc tttatatact ttttttactc
    54841 ttttatctat tttctataaa tctttttcac tcttaacttt tattccttct tcttctaata
    54901 gccttgctgt tatacctttc cctggtatct ttttacctga aaaactacca tcatatatta
    54961 gattacatcc acaagagggg ctaccctctt ttagtattgc ttcgctacat acatataaat
    55021 ttgctatttt tagagtttca ttagcccctc ttacaaagtt ttctgttaca tccttattat
    55081 ctttagtaat tacttttcca tcaactatct cagcaggtgg tcttggtgta gatagaccac
    55141 ctaactgctc tgggcataca agtgtaaatt ctttgccttt taaatattcc ttgacttttt
    55201 cattatcatt attatcgcca ctatatttac aatttattcc tattaaacat gcagatacca
    55261 atatcataaa aatgtgctcc tatacaaatt atatatattc tcatacaaat tactaatgta
    55321 ttcttataca aattatttta atttaacaat tgttactcct gctccacctt ctccatattg
    55381 accacctctt tgtgatttta catgtctatt tcttcttaaa atgtcttgta gccctgcttt
    55441 taatactcct gtacctattc catgtattac tgttacagac tctaaacctg ccacatatgc
    55501 atcatcaaga tacttttcta cttccattat agcttcttct aggtttaacc ctctaaggtc
    55561 aacttcattt tttacactac cagattttga ccttataatg tttctcgttg atttagttac
    55621 atttgttgaa acatctttgc gtgttttttg taaagactta aaaggtagag tcatcttcat
    55681 tataccaatt tgcactactg cttcttttct ctttttatct actgaaacta cactaccatt
    55741 ttgatttaaa gttattacct taacttcttc acctggcttt aagtctttta tctccttatt
    55801 tgataccttt ggaactatca tactttttac tgttggctga agacttccca tagagctggt
    55861 caattctttt ctaagttctt ctatcttacg attcttttct tttgaagctc tttcttgttc
    55921 aagacttcta agttctttta ttataatatc tacttcttct ttagcttgtc ttataattga
    55981 aaatgcttct gatttagctt tttcaatcat cttatctctt tgactgacca atttttcaag
    56041 cttttcgtca tactctactt tcagtttttc aatctcttct tttaatcttt cagcttcttc
    56101 tctatcttct actgctttga ttctattctt ttcaacattc tgtaacacat cttctaaagc
    56161 tatgttttct gtatttatat attctttagc acgtgaaatc acataatcac ttagcccaag
    56221 ttttctagaa atctcaaacg catttgattt tccgggaaca cctataagta acttatatgt
    56281 tgggcttaaa gtttctatat caaattcaac tgctgcattt tctacacctg gtttagtaag
    56341 agcataattt ttaagctcac tatagtgagt ggtagctata catttagctc ctacagaatt
    56401 tatatcttct aatactgcta ttgcaagggc agctccttca acagggtctg ttcccgctcc
    56461 taactcgtca aatataacta aagagtctgc tgttacgttt tgtaatatag atactatatt
    56521 cgtcatatga gatgaaaatg ttgatagact ctgttcaata ctctgctcat ctcctatatc
    56581 tgcaaataca ttatcatata cacacatact acttccataa tcagcaggta tatgaagtcc
    56641 actttgtgtc ataagtgcaa atagacctac agtttttatt gtaacagtct taccacctgt
    56701 gtttggacct gttatcacca atgtatggaa gtctcttcct aaataaattg tatttgctac
    56761 taccttcttt ttatccagca gtggatgtct tccatttttt atgtttaaat atttatcctc
    56821 atttaaagtt ggttctattc ctctcatctg tatagaaagt tttccctttg aaaatgcaaa
    56881 gtccaatctt ccaagtatct cttgattaga aattaagtct tcactaactt ctccaaccat
    56941 agcagaaagc tctgataaaa ttctttctat ttcttcttgc tcacctagtt ttaactgtct
    57001 caattcattg ttcatctcta ctatagtcat tggctctata aaaagtgtcg caccagaaga
    57061 tgactggtca tgcactatac cagctacttg cgacctatat tcagatttta caggtactac
    57121 aaatctatca cctcttagag aaattattgc atcttgtaag tacttttgat aagtagttga
    57181 acttattatt gaatttaatt ttgacctaat ggattgattt ttttgggcta ttcttcttct
    57241 gatatctcta agtgtacttg aagcattgtc agatatttct acttcactaa ttatagcatt
    57301 gtatatctgg tcttctatgt ccttgtatac atatagagaa tttgatagag attgtattat
    57361 tggataatta aaatcttctt catcactact agataagcta tttcttaatc ttctagccac
    57421 tcttaaggta tctgctatca taatcagact tcctgggtca agagaagcac ctatataagc
    57481 tctctttacc ttatcttcta tatcatgaat accttccaac cctactgaac ctctctttat
    57541 aataattgat tgagcttcac tagtttcttc tagcatagat ttcacttcta caaaatcagt
    57601 atttggtact aaattttcta tatattttag acctaaagaa gatgaggctt tcttctttaa
    57661 caaatctatt attttattgt attctagaac tcttaacgat ttctcattca ttttctatat
    57721 tcaccatcct cgatatttta acttttttat ttaattttaa aaatgtatgt tttcaagcat
    57781 ttccaataaa aactgcaagt tttatttctt tttcatttct aaaattatta tattttttct
    57841 cttttagata tattttacac atattttgta ttatactatg tatgtagcta tctatatatt
    57901 atacataaac atgctttatt tgtaatataa tctgttaaaa aatcttcttt aatattttta
    57961 aaggagttta ttttagctta taaaaaaaaa tagctactta tatagataaa ttaaggagga
    58021 acatgagtca tgggaaacgt attagaagga ttaaaaccag aaagtgtttt taaaaacttt
    58081 gagaaaatat ctcaaattcc tagaggttct ggaaatgaaa aaggcataag tgatttttta
    58141 cttagctttg gtaaaaattt aggtcttgaa actattcagg atgaaagctt aaacataata
    58201 ataagaaagc ctgctacaaa aggatatgaa aattgtccag gtgtagttct tcaaggacat
    58261 atggatatgg tttgcgaaaa agaaaagaat gttgaacatg attttcttaa agaccctata
    58321 aaattaagaa ttgatggtga catgatatat gctactggaa ctactctagg agctgacaat
    58381 ggtatagctg ttgctatggg tatggctata ttagaagata atactttaga gcatcctgca
    58441 ctagaagttt tagttactgt taatgaagaa gatggtatga atggtgcaga tgcactagac
    58501 cctagcttaa ttaaaggtca atatatccta aatatggact ccgaggagga aggatactta
    58561 ttagttagct gtgctggtgg taaaacttgt gttgttagtt tacctgttga atacaaaaaa
    58621 gttgaaggtg acaaacaagg attattagtt gaggttactg gactattagg tggacactct
    58681 ggtatggaaa ttgttttaca aagagcaaat gctaacaaag caatagctag agtattaagt
    58741 gtattgaatg ttgattatga attagcttct gttgatggtg gtactaagca caatgctata
    58801 cctcgtgaag ctaaatgtgt aatagctgtt aataaagctg atgttgaatc tgctaaaaaa
    58861 caaataaatg acattttaac tgcatttaaa catgagttta ctacttctga ccctggcatg
    58921 acttactcag tagctgaaac ttctgtagac aaagttctta ctaaagattg caaagaaaaa
    58981 gttgttcaaa tgtcttgctt aactcctcat ggagttcaat cagtaagtct tgatatagaa
    59041 ggattagttg aaagttctac taacttcgct ataattgaaa ctaaagaatc tactattgaa
    59101 tttttaactt ctgttagaag ttctgttatg tctattagag atgaaatcgc tgatagaata
    59161 agacttttgg ctcaagcttt aggtgctaat tacgacctta tagctcaata cccagcttgg
    59221 gaatttaaaa aaggctcaaa attagaaaaa atatgcagtg aaacttatga gaaattaact
    59281 ggtaaagttc ctactgttat ggctctacat gctggtcttg agtgtggatt attacttgat
    59341 aaacttcctc atgctgaagc tatctctata ggaccagata tgtttgatgt tcatactcca
    59401 aatgaacatg ttagtatccc ttctgtagct aatgtttggg attatgttat tgaaatatta
    59461 aaatctatga accaatatta aatttaagtt ttgattctaa gtagatttta attttaagta
    59521 atctatataa aattaactct gtaaattaat actactgtta gtataatatt tactttcaat
    59581 attaacttat agaaataaag cctaatgata gataataaca tgtatcatta ggctttattg
    59641 taatttaaat attattaagc tttattctgt tttaaaatta attcttatac tattttaaat
    59701 ctatttcttc cttgtctctt agaatcataa agagcattat ctgctatttg atacagttca
    59761 tcatactctt gaccaggctt tgctataact acccccatac taatagataa actttctcca
    59821 tttggcaact taatgagatg aatatgattg tatacatcat tacatttatt aataagttct
    59881 tccttattta ttatatcatt gatataaaca ctaaattcat ctccacccaa acgacctact
    59941 atatcatttt ttgcaaaact ttcatcaagt acctttgcaa catcaataag tactttatct
    60001 cctaacaagt gaccataagt atcattaatc gacttaaaat aatcaatatc tataatcaat
    60061 aaagcaccat ttttttcagt tgataaattc aacaaatttt gtgcagttaa ttttctaata
    60121 tatgctgcat tataaatatt ggttaaacta tccctttgag ccttatctaa caatctattc
    60181 ttttcctctt tttcagaatc aatattacat attttcccga ttacatacat tggtattttt
    60241 ctatcattat aaattatttt tgaagtaact ctaatccaat gaaaagtatc atcaagcata
    60301 atagaataca tttcagttgt tccattttct tgtgatttta ttacatcaaa aaacttttta
    60361 ttatattctt tccttatttt atctctttca ttttctatat tgccattttc actttcctta
    60421 tcatttttat ccaaaccata ataagtctca ataccctttt ctggcataga aattatcaat
    60481 ttatcttgct tataatcata ctcaaaaaag tattcacttg tcatttcata caactgagta
    60541 tgttttttga gttctaaaga tatcttctcg ttcatacttg tacgagtatg caaaccaaat
    60601 gccataaatc caataataca aattaataaa ctggctacaa taaaaatagt ctcaattgga
    60661 ttctgttgca taatataaag caacgagaag tcttgtctat atgtagtatt ttggtagaca
    60721 attgattgca ttttttctga tgaaatactt ataatagctt tattaaatat attcaataat
    60781 tcttgtttat cttttttaat tataccaaaa caaatactct ttgctttata agtttgagga
    60841 actagacgca catttttata cttaggttga ttcatatagt actgcataga ataaccttcg
    60901 ccataagtgt aatctgcata gcctttatta acagcttcta tacactcttc taaattatca
    60961 taccaaacta tattctcttc aaactgacca taataattaa tacctttggc tagagctaca
    61021 cgttttccat ctaaactatt ctcatttaat ttattattaa tcatcatagt atattgagta
    61081 gaaagaaaag gccgagacat aactatatta tgttcacgag agtattcata atcataaatc
    61141 attcctgcta caatatcaat ttcacgcttt ttagtcatgt tttctaaatc ttcttgagat
    61201 tttacaggca caagttcaaa ttctaagcct gttttatcac atatatgatt taacaaatca
    61261 attgatatac ctcttaattc acctgtatct ttatctatat tttgaaatgg tggtttgttt
    61321 aaaagtactc ctacttttaa tttttctgtc tctttaatgt aatcagtttc ttcatcagat
    61381 aaaaacattt gattgttctc tggtgtaaag tatttttcat ataaagtagt tgaaaaatat
    61441 gggtctttct gttcaatatt attaattgct gagttaagct tttgagttaa atttgtacta
    61501 cctttaggag taatgaaaca aaatggtttt gatgaaaatt ttgctacagt acgtacacct
    61561 tctagtgggt tcatactcac attaagaagt acatctgctt taccactctt tagtgcttct
    61621 agttgctcat catttgtttt acaatatacc aattcaggtg acataagatt catcttacaa
    61681 tactcatcta actctttaag cctagtatca gaattttcta ttacagcaat acggattttt
    61741 ttcacatctt gtgaactcat tatgttatca atatctgtat tttcatataa tgcttgtagt
    61801 actgtatttg ctactccata attattccct gcataattat atattttttg cattggctca
    61861 ttgtataaca tacctcccat tatatcaatt tcaccatttt ctaacatctt cattaatttt
    61921 gtaatagatt catttatatc tccaggaact tgaacaaatt cataattcca tccagtatac
    61981 tgtgcaattt ctagtaaata ttcatatgta tacccaaaat agttaccttg ctcatctatt
    62041 tcagttaaac ctttttgaat aggataagca acacgaatgg tacgattatc attacctata
    62101 gcgttgatac caaaagaaaa tatgcaagaa gtgaatatag atgtaattac aataattaat
    62161 aaaagtaatt tttttaaatt cactacacaa tcctccatat agttaagatt tacagtataa
    62221 attactgcat aaacttgtag acatgtaaaa atagattagt atataaaagg atatataaat
    62281 ctacttagaa atttaaatat ccttaatata tacaatatat ttaaattata actcatttat
    62341 atgtctatta caacaaattt accctgctaa atacctactc tatatcccat aattttacaa
    62401 gttgtagtga agtttaagtt ctatctcacc tcaaatttag cagtgtttct atttacagtt
    62461 cttttatatt tcacatctgg ataacccaat ataaatgaag tgataacagc ttcgttctcg
    62521 ctcattccta acagttcttt tatctttggc tctacatttg atgccataac aaaaaatcca
    62581 ttataacaaa ttcctaatcc ttgagaatag gccataagtt ccatattaga tgcagccagt
    62641 cctccatcta cataagcact tccacctaga gacatatctc ctacaactac cataagtagt
    62701 ggggcatcat aaaataaaga atcatttccg ttctctttat atcttttgta cattttctta
    62761 aatgtatttt tatagataga acgtacaggg tcattgtcat cagtatctaa tgccaaatta
    62821 taaagacctt gtattgccag ttctttcact tcttttagct tttcttttac taatatgtat
    62881 cttataggct gtctattacc acctgttggt gtgtatctac cagcttccac tatgtttttt
    62941 attttttctt cttctacctc tatatcttta tattgtctta tacttcttct aaatttaata
    63001 aaattcaata acttttcggg ttctaattca aaactttcac gattgtattc tattacttca
    63061 tttttatcaa atccttgcat ttctattgca tctgttgggc aaattgccat acagtgacca
    63121 cagttaatac agagaatatt tttaaccttt gctttatcat ccttaacttt tattgcattt
    63181 acaagacagt ctgattcaca cataccacag cctacacatt tttctaaatt tatgtctatc
    63241 attccaaatt attcctcctt ttaaaaaatt tactttagta taaaacaaat agttgtctaa
    63301 gtcaattttt atttttttaa caatatacta gccttaacta cactttaatg gagaaaaata
    63361 tacataaatt ggaacttaaa ttagaactta ttcaaagtaa aagataaaag aagtagatgt
    63421 ctaaaagtga actttttagt taattagata ttctttattg tatgaaatca agtggatatt
    63481 tatcatttca acaataaaaa aggcttacct ctattttgga tatgtccctg tcaagtagac
    63541 agactaaaaa aaggctatct ttatgcactg agatagcccc ttttcccaac tactattgtt
    63601 tatcttaata ttagtcaata aatttaattt gctataacct gtaagttaca ttttaatttg
    63661 atgtaacttt aaattacatt tttaagtaat atctttaaat tatattctta aaatatatca
    63721 ttaaactaca ttttaattaa tctaaaaact atatcttaat taatctaaga aacttacatt
    63781 ataatctttt agtttcccat tatcatatac aatctttgca ctaaagatat ttccagtctt
    63841 agcccaattt aagaacagcc tgtcaccttc ccacatattt aaatcgaata ttttatcatt
    63901 atcaacccaa attaaatttc cttctttaca atcatttaaa tctttttcag ataattcacc
    63961 ttcaaactca tctgagaaat acaaaaacat ataccaatct tcttcatctt taaattttgg
    64021 aaaagttatc aaccctttat atgacaatga tttaagagta agaccagtct cttcttttac
    64081 ttctctaatt acacattctt ctggggtctc tccttgttca aactttcctc caactcctac
    64141 atacttacct tcatgtatat catctttctt tttatttctg tacaacatca aagtcttgtc
    64201 atctttttct atataacaaa tagttgtaag tttcatgtat ctcgccttgc tttctcttta
    64261 tattctcaac taattatttt cagcactttc aagcacatca cttatattct tcattgcatt
    64321 aagagaaagc tctgcaaatt catcaaatgg aatccctata tcttctatac ttctcattgc
    64381 atctctattt acatttgaag caaatctcgt ttctttcatt cttttaataa cagacttagt
    64441 ctttacactg gtaagttttt tatctggata aactaaagct atagcagtta taaacccagt
    64501 tatagggtct gctgcatata ttgctttttc cattaggcta gttcttgtaa ctcccattcc
    64561 atcatgatga ccaagtattg ctctatacat ttcttcgtca ccgaagtttt cttttttaag
    64621 cagttctact gttgttgtag catgtccttc acatatttct cctggctttc ttccaactat
    64681 atctgaatcc aaatcatgta aaagacctgc cactgcccac tcttcttctt tttctggctc
    64741 tagtcttttg gctaattctc tcataacagc ttcaacagca taacaatgtt ttctcattct
    64801 atcagtttct aaatacttaa ataaaatttc taaagcttct tctctcattt tcaccaatcc
    64861 ccctgttttt tcacatatat gatattttta tatattaata cacataaatt caagttttta
    64921 tatatattca tgtatatttt tcatgttata tctattctac acctttatag tagtgtcctg
    64981 caactgttcc aatttcatct aatttcttat acaagtctgt agcctttttt ccaagtttat
    65041 aattattact caatacctca atgtgagctt caataacctt tttaaccatc tcactatctt
    65101 caactgtaaa atctatccta aatacatcta ttccaatttc ctctaactca tatagattgt
    65161 ccaacataca agtaaccttc gaattgtaaa ttgtacttct acagaatata tcttgtgtta
    65221 tcctataact tgcatccgta aagtctctta aagcataact actttcctta catttagcaa
    65281 ctctcttgtc ctttttacaa tctctaacaa ctactcccat aggacagtat tctgtaacca
    65341 tcataggagc atatccatat attactgctt caatttctac atctgtatat tttaaagttt
    65401 gtttaatttc atttaagttt agttcttgtg acaaacaaac tgtacttgct ccctcttctt
    65461 tgaagtggtt tatactttca ctattgaatg catttaagta gcaatctata tttaagtctt
    65521 ttttcttaaa gtattccata gagccccagt taccaatttg aaccttatta attcctttta
    65581 tattatccaa tatctcaaat tgcttgtact ctttatttct aacaatcctt ggtgctgaat
    65641 agattaattt tttgttagtg actgctgtat tatagtggtt cttattcaaa gtatctattt
    65701 tacttgtatt tgacaaagta tctatgttat ttgtatttga acccattagt tctttaggag
    65761 tatctaaaga cgaagaagta tctaaatcca tagaaatact tgaatctata gaaatatttg
    65821 aatctataga aatacttgag accatttgta aagcttttga taatgtattt atatcttcat
    65881 aatagattaa atctacatta taatttaata ctgcttctaa ttgctccaag ttcttaactt
    65941 taactctaat cttaggaact gtatcaagtt ttttctgttt atttactcta tttggctggt
    66001 attttaatct attcttctta aattttctat cttttatctt tattctttct tcatctaaaa
    66061 gctcaataca atcccttctc atttgattta acacacttat aggcatactt acaccttcat
    66121 ccaggtcaat ttctatctct tttaacttat atggtgtatt tccaagcttt tgaatttgtg
    66181 tttctatttt ttctttactt aaagccacct ttatagcttt ttcaactatt ttgtctcctt
    66241 ctaccaccga tttatttcca caaaaatcac ttataaaaag ctctggcttt ttacctagtt
    66301 taatactcac ttttgcacgt atattagttt ttatgaactc tttatcttgc tgaaatgtag
    66361 cttgtactct atccatcaat tcgctgtcag aagtcttata tataagctga tttctctttg
    66421 cttctccaac aaaatctaat tctatcaaat cccctttatg tgctattgta gttatctctc
    66481 catcctttat tattcttcca atagtacctc cacctaagtt aattccatca cctttcttaa
    66541 gcgtattttc tagcattact ctaagtcttt tgttctttct attataatct aaaacttttc
    66601 caatatatag cccttgatta ttaggtctat tagagttcat tatatcctta ccaacttcac
    66661 ctaatatata tccttttgta aactttctat taaatatggt atacaaatta tttattattt
    66721 cctcagaaat acttattttt ttcttatcta caaattcatt aatcgcttct ctatatcctg
    66781 aaaccacagt agctacatac tctggctttt tcattctacc ttcaattttt aaagataata
    66841 cacctgcttc aattatttta tccaaatctt ctatagtact taaatctcta ggactcaaca
    66901 aataatctcc attacttttt actacttctc ctgtatttat atctatcaac tcatactttt
    66961 gtctacatgg ctgtgcacac ctacctctat ttccagacct attgcctatc atactactca
    67021 taaggcattg acccgagtaa catacacata aagccccatg tacaaaaact tctatatcta
    67081 cagttgtatt ttcacaaatc cattttatct catcaacatt taattctctt gctaaaacaa
    67141 ctctatcaaa ccctacactc tgaaggtatt ttacatcttc taaggaatgt gctaccattt
    67201 gagtgcttgc atgtagttca aagtcaggta atagtttttt tataagtctt gccattccta
    67261 tatcctgtac tattaaagca tcaatatcta tatcgtataa aaattttaca tactctacaa
    67321 aatcttctat ttcatactgt tttatcaatg tatttacagt aacaaagact tgcactcccc
    67381 ttatatgaga gtatttaaca gcctcaatca gctcatttct atcaaagtta tttgcagatg
    67441 ctctagcact aaagtcttta ccacctaaat acacagcatt tgctccgttt tgaactgctg
    67501 cttttaatga atcaaaagag cctactggtg caagtaattc tatttttttc atatttttct
    67561 cctctattta tacttgttag gttaatataa ttatatctat aacttaaata tttgtattaa
    67621 atttatatat ttcttactat attttaaatt cttcaatcaa tttatatatt agttatttat
    67681 atttggttca tttgagttaa catatacatt atttactata tttagtatat ttctattaac
    67741 ttatatattt attactgtat tttaaattct tcaattaatt tatatactgc ttactaaatt
    67801 taaaacattt taattaattt gtacactgtt tactatactt gaaatacttc tattaatcta
    67861 tatattgcct actatactta agacatttta attaatttat acactgctta ctatatttta
    67921 aattctttaa ttaatctata caatatttgc tatatataaa gtatatcaaa taacagcttc
    67981 atttttttgt aaatttacag aaagttaatt ttcattaaat gaatcatctt tattgataaa
    68041 cataattcca aagaccactg ccaaaataaa aaaacatatt agtattgatt tttccacgaa
    68101 aatttttgta aaaaaagttc ctaaaatagc tccagatata aagaatataa taatagcata
    68161 atactgtaaa ctctttttta tcataaaaat attcttagta tgtatataat gaaataaagt
    68221 ttctgtagca cttcttaaat ttccagtaca cattgtcgtt gcaaaactat tcccatttac
    68281 ttttctaaaa ctctctactt gcattgaaca aataaaagaa atagcaacat ttacaaacat
    68341 attaaatctt cctctaggaa taaatgaaac aataagtatt gtaatcattt caattataat
    68401 gataacctga cgccaatgaa tctttgtctt attatttgta aaatactttc ttatcttctc
    68461 ggctataaat acacctaaca taaatgccaa aataggaatc aaataataaa atgattcctt
    68521 tacattacct tctgctatat taagcccaaa caaaactata tttccagttt gtgcattagc
    68581 aaagacttta cctcttacca cataagtata aatatccaaa aatcctcctg ttattgccaa
    68641 caaagaacat aaaaagaatg attcagacat ctgactcttg cttgtcatat ataaacctct
    68701 cgctttctaa tgatagatac aaaatcaaaa tcattttaga ttctattttt cattgatata
    68761 aaaaaattat ttatatttaa atattgtcta tatttataca tcatttatat ttatttatat
    68821 ttaaacatta tctatatcta tatagcattt atatttatac attaaaagaa gctgtctcaa
    68881 aaaacaagag acagcaaatc ttttagttta ttccacattt tttgcatcat tatttaaccc
    68941 tgtacatttt aactgtaaat cataagcttt gttttgaaac tcagaagcta agttttcagc
    69001 tatagtagct ctttcatttg cttcttcaag ttgagtactt aactcctcaa tcttgttttt
    69061 ataagcatct aactctgctc tagaaccttc tgtcgtatta ctaagttcga atatttcttg
    69121 ctttttattt tctataatct caattaactc tttcatctta gtttcagctt cacgattttc
    69181 tgcttctttt tctgctatcg taagctttaa agatttgatt tctaattgaa gctcttcatt
    69241 agatgctcca accttcttac tcaattcttc attcgcttta atcaacttct cattctcatc
    69301 tgaacattca aataaaaggt ctgatatatt taatgcagtt aatatcgcag caactgataa
    69361 gctcaatttc gggttttgac gtgttatttt atccatttct ttgtctacaa aatcagcaat
    69421 actaatcata aacttctctg atttgtctcc aaccattgga tattcagcgc catggatttt
    69481 aaccattact ttgttcatcc taacctcccc cgacattagt tgttaatttg atcttaagtt
    69541 agcatttaat ttttcgctta attcacttaa tatcttatca tgcaccttag ctacatcttc
    69601 atctgttaga gttttatctt tacttctata agttattgaa tatgcaattg acttgtatcc
    69661 agcttctatt tgagaacctt tgtaaacatc aaataacttg tagctttcta ctaatccttg
    69721 accattttcc tttattatat cttctatttg ttttacaaat acatcatctt taacaataag
    69781 agctatatct cttgatgtag atggatattt tggtaatggc acataattct ttgttctatc
    69841 agaattatca aatacaaagt caatatctat ttcagcgaca taaactcttt gacctagatt
    69901 gtagttttct ataacatctg gatgcaattc acctaatgta cctacatatt tattattata
    69961 cactatttta gcacatctac cagggtggaa ggtagtatta ttatcttgag gttcaatttc
    70021 ataaccttta aatccgacat ttacaagtat agtttctata gttcctttta gtgcaaagaa
    70081 gtcaacatct ttaccataca tacctacaca cattctattt tcttccttag gtaattctga
    70141 atcttgtggg atgaatatat gtccacactc aaatgcagat acttcttcta ttttatgaga
    70201 tacattagtt gataaaacat ctaacatatt tggtattaaa gtagttctca ttacagaagt
    70261 ttcttctcct aatgggttaa gtaatttaac aaaatttctc tttgcattac cttctggtac
    70321 tcttatctta tctactccct tagggcttac aaatgaatat gttaatattt catttaatcc
    70381 tacagcagtt gaattatctt ttaaagcatc catgaatttt tgttttgaag ttttaattcc
    70441 tgctgtcgta tttccttcta attgtacaga aggtatattc tcaaatccat aaattctagc
    70501 tatttcttcc catacatcag cttcttgttc catatctgtt ctaaagcttg gtacatctat
    70561 ttctaattta tcattagcta ccaaattaca tttaaactct aatgattcta aaattcctac
    70621 aaactgctcc attggtacat ctacacctaa taggtggtta attctttgag gatttactac
    70681 caatttttta ggttctggtt tatttggata tacatctaca acacctttta aaacttttcc
    70741 tgctcctaac atttcaacaa gttgtgcagc tctatttgct gctatctctg caagattagg
    70801 gtctaagtct ttttcatttc ttgaagatgc ttctgaccta ataccaactt ttttagctgt
    70861 cattcttatg ttttctggtt tgaaattggc actttcaaaa agtacagtct tcgtattaga
    70921 agttatttct gagttagcac cacccattac accagctaaa ccaagtgatt tttctccatt
    70981 tgttataact agcatatctt tgtctaatgt tctctcaaca tcatctaatg ttacaagttt
    71041 ctctccatct ttagcatttc ttactactat tcttccagtc tctacttgat ttatatcaaa
    71101 agcatgaagt ggttgaccaa gctctaacat tacgaagttt gttatatcga ctatgttact
    71161 tataggtctt actcctgctt ctgtaagtct tctttgcatc caatatggag aaggttctat
    71221 ttttacatct gtaaccattc tagcaacata tcttctacat aaatctggat tatctatctc
    71281 aactttgaaa tctatctctt cgtcactttc ttttacttcg atttcaggat attttacttt
    71341 tgttcctata gttgcagctg cttctctagc tatacccatc atgcatttac aatcaggtct
    71401 gtttgaagtt aattcaaaat ctattaaagc atcttttaat cctaaaacat cttttatatc
    71461 ttttcctaat tcataagaat cttcgtggtc taaaatatat ataccacctc ttttatactc
    71521 ctcaatgtaa tgttcatcta tacctagttc agctgctgaa cacatcatac catctgataa
    71581 ttcacctctg aaatcagtct gtttgatttc aactcctcca ggtaacttag aaccatttac
    71641 agctactgga atataatctc cttctgatat atttgtagct cctgtaacta tttgaacaac
    71701 tttatctcca atatctactt tggttacaac caacttatca gcatttggat gttgttttat
    71761 ttctaaaatc tttccaacca atatattttc tatttcttca ccataataat ctattgtttc
    71821 aactttagtt cctgtcattg tcattttatc agcgaactct tttacatcca tgtctatatc
    71881 aacatagtct ctaagccatt ttaaagatac taacatctac ataccctcct aattaaaatt
    71941 gatttaagaa tctcatatca ttttcgaata ataatctaat atcatctatt tcgtatttaa
    72001 gcattgcaag tctttcaacc ccaactccaa atgcaaatcc actgtaaact tctgggtcta
    72061 ttccacaatt tctaagcaca tttggatgaa ccatacctga acctaatatt tctatccaac
    72121 cttcatattt acacattggg caacctttac caccacattt gaaacaagta acatcaacct
    72181 ctgcacttgg ttctgtaaat ggaaagttgt gaggtctaaa cttagttttg atatcagaac
    72241 caaacaattt ttcaacgaag atatccatag ttcctttaaa ttctgccata gtaacatctt
    72301 ttccaacaac aagcccttct atctgatgga acattggtga gtgtgtagca tctggcgagt
    72361 ctgacctaaa acatctacct ggtgcaatta cttttattgg taactcttga cttctcatag
    72421 ttcttacttg aactggagat gtttgagttc taagtaatac cccatcattg atatagaatg
    72481 tatcgctcat atctcttgat ggatggtctt taggagcgtt taatgcgtca aagttgtttt
    72541 caacagtctc aacttctggc ccttctgcta tagagaatcc cattccgata aatatatctg
    72601 ttacttcatc tataatttga gttattggat gcttcttccc aacctttaaa acttttcctg
    72661 gttgagtaac atctatcact tcctctttta attttctttc tttttcaata gcatttattt
    72721 cttctttttt ggaatttatg ctaagttcaa tgttttctct tacctcattg gcaaccttac
    72781 caactactgg tctttcttca gcagataatt tacccatttc tttaagtatg gcagttatct
    72841 cacctttttt tcctaagtac ttaactctta aactttctac actttctatg ctttgtgctt
    72901 cttttatttc agccaaagct gcttcacgta aagcaagtaa tttttcttgc acacatatca
    72961 ccctttcgtt tttttgtata aaaaaagccc ctcaatccct gtctagggac gaaaggctat
    73021 agtttcgcgg taccacccta gtagtttaac aatttaaaaa tcatcaaacc acctctaaca
    73081 aacttaacgc gtttttaacg tcaaagccta ctgtaaaatt tcagctctgt tactccagag
    73141 ggaacttctc atgacctctt agaaaacact cccagcctag gtgtttatct ctttactaag
    73201 tttaatcaaa atactttcct ctttcattgc atttacaata ttatattgtt tattttagta
    73261 ttatatcatt tccattcaaa ttatgtgact atttttaata tatatccaat acataat
//
LOCUS       DAMJXI010000013        72843 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.013, whole genome shotgun sequence.
ACCESSION   DAMJXI010000013 DAMJXI010000000
VERSION     DAMJXI010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 72843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72843
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.013"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            86..1282
                     /locus_tag="PC465_001161"
     CDS             86..1282
                     /locus_tag="PC465_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HDF2648484.1"
                     /translation="MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHE
                     KAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFAT
                     SVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSS
                     YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAA
                     VDGGKCVDTSMGFTPLEGLIMGTRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVY
                     GMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVG
                     ENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARD
                     TLRLVK"
     gene            1375..1899
                     /locus_tag="PC465_001162"
     CDS             1375..1899
                     /locus_tag="PC465_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HDF2648485.1"
                     /translation="MKVSIEKINRKETDKIDLNFCEKIDTISYCDEIYKLVSPVNLKG
                     KVSKTNKGLYLDIDVNFTIVDNCSRCLKEVEIPLEYSIQGFLVKEEDYDEDEFEEFDP
                     FIFDGEEIDLIDIIEQTLDFNVPHKVLCSENCKGLCQVCGANLNEEECSCSEITNDEE
                     YIDPRFAKLKDLFN"
     gene            1924..2100
                     /gene="rpmF"
                     /locus_tag="PC465_001163"
     CDS             1924..2100
                     /gene="rpmF"
                     /locus_tag="PC465_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HDF2648486.1"
                     /translation="MAVPKRKTSKSNTKMRRAANSKMEATGFVSCPQCHEPKLPHRVC
                     PDCGYYKGKEVVSK"
     gene            2307..2864
                     /gene="fapR"
                     /locus_tag="PC465_001164"
     CDS             2307..2864
                     /gene="fapR"
                     /locus_tag="PC465_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HDF2648487.1"
                     /translation="MKKKSKAQRQKELIDMLKTDPFYTDEELSSLFDVSIQTIRLDRM
                     SLNIPELRERVKSIAETQSSKVKTLGVKEITGEIIDLSVGRLGISMLEVTQDMIYSKT
                     NTLKDTYIFSLADSLAMAIIDAPKVIMRVANVKSFKLIEQQDRLIAKAEVYRNIDKKH
                     YVKVVINNKAQEQIFRGKFIFEELD"
     gene            2875..3897
                     /gene="plsX"
                     /locus_tag="PC465_001165"
     CDS             2875..3897
                     /gene="plsX"
                     /locus_tag="PC465_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HDF2648488.1"
                     /translation="MKIVIDGMGGDNAPKSNVEGAVNAIKEYQVDLIITGDKDLLEKE
                     FSNYEFDRNKLEIVHTTEIIENEDKPVKAIRSKKDSSMVVALNLVKEGKADAIISAGN
                     TGALLAGGLFVVGRIKGIDRPCLCSAIPNVKRGMTLIADCGANADCKPKNLVEFAAMS
                     NIYSRKVLGLENPKVALANVGLEEGKGNDLVKRSYEEIKKLDLNFIGNVEAREVINAY
                     TDIIICDGFTGNILLKSAEGVALSVMSLIKETFMASTKSKIGALLIKDDLRKLKSFID
                     YSEYGGAPLLGLNGGVIKAHGSSDAKAIKNAINQGIKFSKGKVVEDINQFISKYNEEN
                     KNNEDE"
     gene            3923..4909
                     /locus_tag="PC465_001166"
     CDS             3923..4909
                     /locus_tag="PC465_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HDF2648489.1"
                     /translation="MNTKAGILGVGSYLPEQSYDNFHFEKIMDTSDEWISTRTGIKER
                     RFAKESEATSDLASKAALKAIECAKLNVEDIELIILATITPDMSLPSTACIVQDAIGA
                     VNATAFDISAACSGFVYGVTIAKQFVETGCYKNVLVIGAETCSKFLNYDDRTTAVLFG
                     DGAGAAVIGPVNEGGILSTHMGSDGKGKDCLKVPAGGSRLKASKETVEANLHTIEMAG
                     SDVFKFAVRKMAETSLRALEKANLNTTDIDYLVPHQANIRIIQASSKRLELDMKKVYV
                     NIDKYGNMSAASIPVALDEAYREGKIKKGDNVVLVGFGGGLTWGASVVKWTL"
     gene            5018..5947
                     /gene="fabK"
                     /locus_tag="PC465_001167"
     CDS             5018..5947
                     /gene="fabK"
                     /locus_tag="PC465_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HDF2648490.1"
                     /translation="MNKICKILNIKYPVIQGGMAWVATASLASAVSNAGGLGIIAAGN
                     APKEAIKKEIVECKKLTDKPFGVNVMLMSPFVDDIIDLIIEEKVQVITTGAGNPAKYM
                     DRLKEAGTKVIPVVPTIALAQRMEKLGATAVIAEGTEGGGHIGELTTMVLVPQVADAV
                     NIPVIAAGGIVDGRGIAASFALGASAVQVGTRFICSEECSVHSNYKNLVLKAKDRDAI
                     VTGRSTGHPVRTLKNKLSKEFLKMEQNGATPEELDKKGTGALRFATVDGDIEKGSFMA
                     GQSAAMVKEITPCKEIIEAMVNQAREIMPAIEL"
     gene            5963..6913
                     /gene="fabD"
                     /locus_tag="PC465_001168"
     CDS             5963..6913
                     /gene="fabD"
                     /locus_tag="PC465_001168"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HDF2648491.1"
                     /translation="MGKVALVFPGQGAQYVGMAKDLYENNAVAKSVIDEASDALNMDL
                     KNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAQIDLKYNACLGLSLGEYSALVAA
                     DAIDFKDAVCLVKKRGKFMQETVPAGVGAMAAVLGLDRNVLENVVKDIQGGIVEVANY
                     NSPGQIVISGENEKIEEAMVKCKEAGAKRAVKLNVSGPFHSSMLKEAGVKLASELEKV
                     NITKPKVDVVANVNADYYKNEGKDLLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGK
                     TLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI"
     gene            6913..7662
                     /gene="fabG"
                     /locus_tag="PC465_001169"
     CDS             6913..7662
                     /gene="fabG"
                     /locus_tag="PC465_001169"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HDF2648492.1"
                     /translation="MINLTGQVAVVTGGSRGIGKEIAKKLASFGADVVINYTSKEDEA
                     LKTKNEIESMGVKCTSIKCDVSKFDEVNQMIDSVVSEFGKIDILVNNAGITKDGLLMR
                     MKEEDFDRVIDINLKGVFNCTKAVTKPMMKKKYGRIINMTSVVGIMGNAGQTNYCASK
                     AGVIGFTKASARELASRNININAVAPGFIETDMTKVLSDDVKESTLANIPKKSYGKPE
                     DVANAVAFLVSDMSSYITGQVINVDGGMVMQ"
     gene            7716..7940
                     /gene="acpP"
                     /locus_tag="PC465_001170"
     CDS             7716..7940
                     /gene="acpP"
                     /locus_tag="PC465_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDF2648493.1"
                     /translation="MFNKVVEIIIEQLGVEDKEITMETSLMKDLEADSLDAVEIIMAL
                     EDEFGIEIPDTEAENFKSIGDIVKYIEANK"
     gene            7969..9207
                     /gene="fabF"
                     /locus_tag="PC465_001171"
     CDS             7969..9207
                     /gene="fabF"
                     /locus_tag="PC465_001171"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HDF2648494.1"
                     /translation="MNKRVVITGLGCVTPLGTGKEEFWSNIKSGVSGIDKITNFDAST
                     YQTQIAGEVKNFHPEEYISKKELKRLDKFAQFAIVSAKLAVEDANLDLDKVDRERFGV
                     IIGSGIGGVEAIETQHKILLEKGNKRVSSLFVPMMIGNMAAGQVSIFLGAKGPNTNVC
                     TACASGTHSIGDAFKVIQRGDADIMVAGGSEAAVTGLAFAGFCNMKAMSTRNDDPKTA
                     SRPFDKDRDGFVMGEGAGIVILEDLEHALARGAKIYAEVVGYGLTADAYHMTTPAENG
                     EGAARSMNMALKDGNVPLEEVDYINAHGTSTYYNDLYETMAIKTVFGEKAYDLCVSST
                     KSMTGHLLGASGAIEAVVCAMSIEDSFVPPTINIQEVGEDLDLDYVPNQGKEKNIRYA
                     LSNSLGFGGHNATIVLKKYV"
     gene            9433..11151
                     /locus_tag="PC465_001172"
     CDS             9433..11151
                     /locus_tag="PC465_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2648495.1"
                     /translation="MNFRLPKKRLPKKIIFICIILISIILFIKYDQNGLKEREIINKG
                     KYMSESLVADKEYDEAKKVVKTSFESIPEKKYNKVYNEVWDMLKTISYVPDGTKIVID
                     SLEKMRESDVKLSDECRFNIEKRLASVYIMDNNYSKAVDLTVKSIKLAEKLGNNYEKA
                     RLDVDLASIFLKIGGYETGEKLIKDSFKIDIDEGEKNGMVRLYAIINLAEIYVEEGEY
                     DKAIEISSRIKDYKKFVNTDNYNDFDIMASIMQSNAYVGKNNIQKAKTFLEKADYLIK
                     SDRTVYILDKDMYYYMAMGNLEYKSENYNSAIDNYKKSLEISTKRKLTQEKIKNLNKI
                     LNIYEKQGNIESLNEYQKMLINEYKENKSIRDSETSFYIIDKVSNESKLFEKTKKEIK
                     YYKILFTVILIAILGSTFLYNRLKYFKAQNLHDGLTNVYNRKSFDIMYEKYREKDDNF
                     ALVMIDIDNFKLINDNYGHKFGDTVIKGITNTICVMLEQDDKVFRYGGEEFSVLIRNK
                     SGEEVADIIDSIRVAIANKKWNDDVTVTISAGVAHISDSKDVLEEADKNLYKAKQLGR
                     NKVVYK"
     gene            11182..13182
                     /locus_tag="PC465_001173"
     CDS             11182..13182
                     /locus_tag="PC465_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2648496.1"
                     /translation="MKQSIAIVTDKITKLSSFLEENIRLVLGNYIDINHYYLEVLKEN
                     DKIQGDFVLVMNDDRLNSMRKHLVQDSKIIVIRRTLKENEIYGLFSIPNGTEVLVVND
                     TKETTLETISLFYKIGVKNLKFTPYIEGKIYKNIDIAITPGVKGKVPSYINKVIDLGN
                     RYIDISTFIEIINGLRIDVKEIRKNLMAYSESLISLDNGVKDNYRQLFLKIEEQDVIL
                     NLSKDGIIFTSADGIINTFNKEALKILGINENPQGKNIEDIISEDLNILLEDKEIIDE
                     VVFTNKKYINVNKKNIFSMGNKAGIYYNLQEITYIKKLEQNLTNKLREQGQIARYTFK
                     DIKTKNKNMVKCVELAKKISKSDLSVLIIGESGTGKELLSQSIHNASNRSNQPFIAVN
                     CAAVPDSLLESQLFGYEKGSFTGALREGKKGLFELANNGTIFLDEIGDMPPLLQTKLL
                     RVLQEKQVMPIGSHNVINIDVRVIAATNKNLLKMIREGKFREDLYYRLNVLPIDVPSL
                     RNRKEDIITLMNFFLKNNIRLSPEVITILEKYNWPGNIRELQNVASYVSLMCDSMVFR
                     DDLPPYIRVECANNYEDGFGYTRKEFEEILRILYERRESSSGIGRGFIIEKLIQEGIE
                     ISESKVRKVLSYLSECGYISSKSGRGGSQITSEGIKLYNNIN"
     gene            13533..13778
                     /locus_tag="PC465_001174"
     CDS             13533..13778
                     /locus_tag="PC465_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HDF2648497.1"
                     /translation="MKYKTTGTCATEIEFEVKENKVTNVNFIGGCDGNLKGLKVLVEG
                     MNIEDVIQKLKGIECKTKPTSCPDQLSLALENYMNIK"
     gene            13813..14538
                     /locus_tag="PC465_001175"
     CDS             13813..14538
                     /locus_tag="PC465_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HDF2648498.1"
                     /translation="MKPIIGILGNLIIMENGMFPGLERSYVNNDYINAVLKGGGSPVI
                     IPVNTDKEVIKKQIEMVDGVLISGGWDINPQLYGEETREETTFIYPEVDEFDLIAISI
                     ALELKKPILGVCRGLQILNVSLGGTLYQDNNLIEGSYIKHTQSSKRHVATHKVDVKEG
                     SILEGILGKQLLTNSYHHQSVNQLGKGLKAIAYSKDGMIEAIEKEDENFVVGVQWHPE
                     MMVDYCDKMEKLFKYFINICSNL"
     gene            14560..15873
                     /locus_tag="PC465_001176"
     CDS             14560..15873
                     /locus_tag="PC465_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2648499.1"
                     /translation="MNEKNKMGLISIILLGINAVVGAGVFLLPGDAMKSFGVASIFVY
                     IFDMLLVLSMAFCFAEVAGKFNKNGAAYVYTKEAFGDFCGFEVGLMKWVIGCISWGAL
                     IVGFPTSLSAVWAPAGEPHIQKIIIVAMIVGLTIINLLGVSLSKIVQNVITVGKLIPL
                     ILFIGIGIFFIKGVNFTSSTMVPPGAGATEFGAAALLMFYSFTGFESIAVAAEDMENP
                     QKNIPIAIISVIVIASIIYILNQVVCVGILGDSLSSTSTPVADAARICFGNMGAGLVT
                     FGTLVSVGGICMCGAFVNPRSCVALADDKMLPRIFARKDKKGTPYVAIIATMLITIPI
                     ALSGSFAELAAISAVARFIQYIPTSLSVLVFRKKRPELVGTFKTPFGAVIPLIAVCVG
                     TWLLFQASMHQLIMGLGALAIGVPLYFIMKSYNRKVYGENLKKIV"
     gene            16079..16618
                     /locus_tag="PC465_001177"
     CDS             16079..16618
                     /locus_tag="PC465_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2648500.1"
                     /translation="MPTITLKNGVDVLIREGVREDAQSIIDFYNEVGGETHFLSFGKD
                     EYKISLEEQENAIESAKASDNSVKLIAFIDGEIVGIATIDSNQKAKGKHVGVLGIVVK
                     EKYWGIGLGKRLMLDLIEWCKSNGITKKITLVTNEENYNAIGLYKKVGFEVESILKKE
                     CYYNGVYTDLIGMSLLLGI"
     gene            16707..18692
                     /locus_tag="PC465_001178"
     CDS             16707..18692
                     /locus_tag="PC465_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="HDF2648501.1"
                     /translation="MKNLCKISDDYLNSKLKYLKLLSKQYPSISKASTEIINLEAILN
                     LPKGTEHFITDVHGEYEPFVHVLKNGSGVIKRKIEELFSNTIRDSEKKMLATLVYYPE
                     QKLDLIIKQEENIDDFYRINIYRLIELCKYASSKYTRSKVRKLLPENFKYIIEELLHE
                     HVKSEHKEEYYKSIVETIVDIGIAKEFIIAISTVIQKLVVDRLHVIGDIYDRGPRPDI
                     IVDKLIEHHCVDIQWGNHDILWMGAASGEKTCIANALRISARYANLDIVEDIYGINLL
                     PLATFAIEMYKDDPCKEFIPKVNDQSVTTTEKSLMAKMHKAISIIQFKLEGEVIRRRP
                     EFEMEHRLLLNMINYDEGTINLKGKTYKLKDTYLPTIDKKDPYKLTMEERNVIDKLVS
                     SFRGSEKLQKHVSFLFSKGSIYLKANSNLLIHGCVPLNEDGSFMSMNIMGKEYKGKAL
                     MDKMESLAREGFFFKDKAEEKLYGMDIMWYLWTGKCSSLFGKDDMTTFERYFIAEKET
                     HKENKNPYFKLRENEMACKRLFEEFDLELDESHIINGHVPVESKNGESPIKANGKILV
                     IDGGFSRAYQKTTGIAGYTLIYNSRTLQLVSHEPFNSAEEAIANESDILSTTVVVEHK
                     AKRKMVRDTDEGVKIQEEIEDLKLLLMAYKKGLIKEM"
     gene            18916..19884
                     /gene="spoIIIAA"
                     /locus_tag="PC465_001179"
     CDS             18916..19884
                     /gene="spoIIIAA"
                     /locus_tag="PC465_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AA"
                     /protein_id="HDF2648502.1"
                     /translation="MNKLSDEIINSLSTTIREKVEKVSNNNLNIEEIRLRSQKPLILN
                     ANSKDYFYNQKTMTLDLNQQNSYVVTREDVEQTFQIICKYSIHSFMDDIKKGFITLRG
                     GHRVGLVGKAIVEDGQVKNIKHISSLNIRVSREIIGCSDKILSHIIKGKNQINNTLII
                     SPPQCGKTTLIRDIVRNLSNGNEDYGFKGLKVALVDERNEIAGSYLGVPQMDVGIRTD
                     IIETCPKDLGITMLLRSMSPNVIVTDEIGSEKEIKALYTALNGGIGLITTVHGDSIED
                     IQNRKELNRLLDKELFKKVIILSAKRGAGTIEKIYDLEEKRWYFAN"
     gene            19874..20395
                     /locus_tag="PC465_001180"
     CDS             19874..20395
                     /locus_tag="PC465_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AB"
                     /protein_id="HDF2648503.1"
                     /translation="MQIKIIIIAFLIGSSYLIGEQIYKTYTRRHKQLNDLIRVLEILR
                     MDLSFGLYTLEEIFNRIGGNKEFCFWKFFYQISEGLHNEQSKTLEIIISENIDVLSKE
                     TYLGNKEIEELKNLILTLGKSDIESQQRMIDLSIENLKKQTYETKEDINKKGVLYKKL
                     VTFIGIGICIILI"
     gene            20412..20609
                     /gene="spoIIIAC"
                     /locus_tag="PC465_001181"
     CDS             20412..20609
                     /gene="spoIIIAC"
                     /locus_tag="PC465_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AC"
                     /protein_id="HDF2648504.1"
                     /translation="MEISLILKVAGVGILISVLNMILEKTDRKDWAGLTTLAGVIIVL
                     GMVITEISDLFNTVRTMFQLY"
     gene            20625..21011
                     /gene="spoIIIAD"
                     /locus_tag="PC465_001182"
     CDS             20625..21011
                     /gene="spoIIIAD"
                     /locus_tag="PC465_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AD"
                     /protein_id="HDF2648505.1"
                     /translation="MEIMQLIGIAIISTTLCLVIKKDRPEIANFIAIITGVIILLSVM
                     FKLNFIVDSIQDLANKANIPTMYISLIIKLIGIAYLMEFAIQLCKDCGEGNIASKLEF
                     GGKIIVMSMSFPILLSIVEMVVNIIP"
     gene            21096..22301
                     /gene="spoIIIAE"
                     /locus_tag="PC465_001183"
     CDS             21096..22301
                     /gene="spoIIIAE"
                     /locus_tag="PC465_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AE"
                     /protein_id="HDF2648506.1"
                     /translation="MKKRFLPMIIGFLFTFFFVNIFAIMIFANEVPSSEDKEYGETKN
                     SIDKYIDGQLDKLDINEIQDYINKEIVINDVNLKSFVKDLISGEKNILDLFNKDGLKI
                     LMFDEFKASLKVVAVILVLALLSSILKSLENSFSSGAVSQIATYIIFITMVSLTLIGF
                     KDVLQICYDAIDHTVGLMQVIMPILITFLLLIGFPITSTTLNPIFIGGVTFINVFFKN
                     FLFVSITVAFGILIINNLSKNIRLKRFFSFVKQINYVSIGAMFTVYLGLVSIQGLYVT
                     SFDKFSVKTAKFAIGNFIPVVGGFVSDSVDILLSSSQLIKNIFGGIGLILLVGICLLP
                     VIKILSVIVVYKLAAIIVEPVGEDGISNFLNEVANLMIIMLASVIAITVMFFVTVAIL
                     TSISVVSQG"
     gene            22361..22978
                     /locus_tag="PC465_001184"
     CDS             22361..22978
                     /locus_tag="PC465_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AF"
                     /protein_id="HDF2648507.1"
                     /translation="MLEGIKAWIVSVLIGAFIVNIVDMILPSSKIKPYVNLVLNFMFV
                     FIVITPVVGFFSKDMSLEDRILKSMGNYNKQYVDSTNALAKETGNNSLSKGYEDGLKE
                     VLKLKLDEYGYDLEDIELNGANINNIKIKEKNNSAKSNNSSNEENKNNSTKREEENIN
                     SNDKENSKQVFKKGTEYGLNLNEEKLKNDLIKVLDVSIEDIQIDK"
     gene            22990..23544
                     /locus_tag="PC465_001185"
     CDS             22990..23544
                     /locus_tag="PC465_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AG"
                     /protein_id="HDF2648508.1"
                     /translation="MLKNLNDKDKRKVYSLITIAGICVVSLVLLSCFPSSKSDKQVGK
                     TETNKNAEKQVTKEQEKDDLESKLTAILSKIDGAGDVDVMVTFESSEEIQPAFNSNNT
                     TETTEEKDAQGGERTVTTSSENKTMITSNSSDPVVIKTTEPKIKGVIVVASGASDPSV
                     KETLYSAVQTSLQVAGHQVEIYSK"
     gene            23571..24260
                     /locus_tag="PC465_001186"
     CDS             23571..24260
                     /locus_tag="PC465_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAH-like family protein"
                     /protein_id="HDF2648509.1"
                     /translation="MKFNYKGRGFVIITLTAMLVVVGTVNYQLSKKSLLETSKEFKAY
                     EEAQLQKNTDESDSSKTEDSSNIDKQDGKESADIDIVDSKASKVKEKATETSKEIKAQ
                     LSSEKNMKKASYILDMKMNREKQRNELVQDLNEMINNPSTTEESRKEASNMKLNIVKI
                     QEKELQIENLLSTKGYEEALVYISDNKVNVVVNEAKLEKKDAAKIFDLVAEQANVKYE
                     NIKLTNNNSNK"
     gene            24370..24732
                     /locus_tag="PC465_001187"
     CDS             24370..24732
                     /locus_tag="PC465_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDF2648510.1"
                     /translation="MEDNKFGQVKISNDVIATIAGLAALEVEGIETTATLTDKLLKNN
                     GVKIQIEEEDVNLDVMVTIKYGMSIPDTAFKVQENVKNTVETMTGLKVSQVNIHIQGI
                     SFKKDKVDKEEAKATKKN"
     gene            24817..25323
                     /gene="nusB"
                     /locus_tag="PC465_001188"
     CDS             24817..25323
                     /gene="nusB"
                     /locus_tag="PC465_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HDF2648511.1"
                     /translation="MKKDRAQKSTTREYIMKLIYQININKEDFETLEDKVDNFLKDNS
                     EHIINRYKELALQYSKNTNLKLEDTEIEDVIDKKYINTVCKALKENHDKIDELINKHA
                     KNWTVDRMPKVDVSILRLSVCEILYLDTPNKVSINEAVELAKIYCDDKSPKFINGILG
                     SVVDEIGK"
     gene            25307..26377
                     /locus_tag="PC465_001189"
     CDS             25307..26377
                     /locus_tag="PC465_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="HDF2648512.1"
                     /translation="MKLGNNIIIGIDTSCYTTSIAAISLDKKVILNEKIMLEVRDNSK
                     GLRQSEAVFQHINNLGILSDRIKSFKDKFNVEGVCSSKKPRPVENSYMPVFNVGHNFG
                     KLLSSIYGCRFYETTHQENHIEASLLNSKLKNNNKFISVHMSGGTTEILLTSKQDSHH
                     NVCDTNLGKIAKISIKKDDKSKLYNNFGYNIDIIGGSKDISFGQLIDRVGIKLGYKFP
                     SGKYLDENALNCNLKIESGLKTSVRDGYMNLSGLENQVNKIINDNGDNTNQKEYISKL
                     VLDSVVRNMFKSLVYLCETYNVNEVVFAGGVSASKYILRELSMKLRKKHIEAYFTEPQ
                     YSTDNAVGCAIIGLNNFLGERV"
     gene            26374..27579
                     /locus_tag="PC465_001190"
     CDS             26374..27579
                     /locus_tag="PC465_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HDF2648513.1"
                     /translation="MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGN
                     VYLSLKDETSKLNCVIFKSNFNRNLKLDNGVKIIANGYISVYERDGAYQLYINEIEIE
                     GIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRR
                     YPKVNIKLYPVTVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMV
                     AREVFNSQIPIISAVGHETDFTICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKS
                     RMSKSLTNQIELDQYRLETVFNKINNYLDSYTIKDKVIQLDKIYDKIIFGIENNLKLE
                     DEKLVKIGALLHNLSPLATMDRGYSITQKNGKVINSIKGLKVKDSIDIVLKDGNLECM
                     IDKIENKEG"
     gene            27581..27796
                     /gene="xseB"
                     /locus_tag="PC465_001191"
     CDS             27581..27796
                     /gene="xseB"
                     /locus_tag="PC465_001191"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HDF2648514.1"
                     /translation="MNLTYEEAYKRLESILSELESKNASLDESLSLYEEGISLYKHCN
                     KLLDDAKLKISKFNQLGIEEDFKIEEE"
     gene            27799..28686
                     /locus_tag="PC465_001192"
     CDS             27799..28686
                     /locus_tag="PC465_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HDF2648515.1"
                     /translation="MEFKQCLKEKASFVEKVLKEYMPKEEGYQKTVIEAMNYSLSAGG
                     KRLRPILTLEACKIVGGNEDEAIPFAIAIEMIHTYSLIHDDLPALDNDDLRRGRPTNH
                     KVYGEAMGILAGDALLNYAFEVMLAGSINKENPEKYLKAINEIAKGAGIYGMIGGQVV
                     DVESENKQIEKEKLDYIHMNKTAAMMVGCMRAGATIGGANSEQMEEITKYAKNIGLSF
                     QIVDDILDIVGDEAKLGKKVGSDIENHKSTYPSLLGLDKSKEIAHNLIDEAKKSIEKL
                     SDDVDFLKGLAEYIIDREY"
     gene            28716..29153
                     /locus_tag="PC465_001193"
     CDS             28716..29153
                     /locus_tag="PC465_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent PAP2 family protein"
                     /protein_id="HDF2648516.1"
                     /translation="MDFFSEIFNNGALGISLIACFLAQFIKIFTGKEKRIELSRILIS
                     GGMPSSHSSFVTSLATVVGIEKGFNSTDFAIITVLALIIMYDAAGVRRAVGKQATILN
                     QMVADIQHGKHIEQKKLKELIGHTPLEVWFGALLGIVTALILM"
     gene            29187..31052
                     /locus_tag="PC465_001194"
     CDS             29187..31052
                     /locus_tag="PC465_001194"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HDF2648517.1"
                     /translation="MYKYLDKVNSPKDIKNMSIEEMDLLAKDIRKFLVKSVSKTGGHL
                     ASNLGVVELTLALHKVFDSPKDKIVWDVGHQSYVHKIVTGRKDCFVSLRQFNGLSGFP
                     KENESPHDIFDTGHSSTSISIATGIACARDIKKENYSVISVIGDGSITGGMALEALNQ
                     LGYIDTNMIVILNDNEMSIDKNVGGMSKYLSSIIRNSTVEKMTDEVDKILNVTQTGEI
                     LSKTAHRFKDKLMYSFSPQDCSFFDSLGIRYYGPIDGHNTKELIDILRKAKHKKGPVL
                     LHVITKKGKGYRFAEEQPDKYHGVSKFDIKTGVTSAKVKSMSISVGEKLVDMANSNEN
                     IVAITAAMPSGTGLNLFESAYPKRYYDVGIAEQHATGFAAGLAKNGMKPYFAVYSSFL
                     QRAYDQVIHDVCITKKPVTFLIDRAGLVGNDGETHHGMFDLSYLNSIPNIVVMAPKDT
                     REMELMMDLSLKLDCPLAIRYPRGSSYYLDKGEYGEIVLGKYEVLDDGQDTVILCIGS
                     MVKHALEAKEILSREGINPTIVNARFLKPIDEGMLKALLKNHKNVVTIEDNIVTGGFG
                     SRINKFIIDNEYNVNILNIAIPEEFVKHGNIDELYDFVGLSPKSIADKIRKLVIE"
     gene            31185..31997
                     /locus_tag="PC465_001195"
     CDS             31185..31997
                     /locus_tag="PC465_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family rRNA
                     (cytidine-2'-O)-methyltransferase"
                     /protein_id="HDF2648518.1"
                     /translation="MKKRIDLLLVEQGYFESRERAKKAIMAGLVFVDNQRCDKAGTEV
                     KEDCSIEVKGNPIPYVSRGGLKLEKAMKNFDLTIDGKVCMDIGASTGGFTDCMLKNGA
                     IKVFSIDVGYGQLAWKLRQDDRVVCMERTNIRNVTIEDTKQFADFASIDVSFISLKLV
                     LPKAKELVRHDGEVVALIKPQFEAGREKVGKKGVVREKSTHIEVIKMISDFSVENGFE
                     ILGLDFSPIKGPEGNIEYLIHLRNGNEGYEFDGETYNNKIVEVVEASHNLDK"
     gene            32017..33696
                     /gene="recN"
                     /locus_tag="PC465_001196"
     CDS             32017..33696
                     /gene="recN"
                     /locus_tag="PC465_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HDF2648519.1"
                     /translation="MILELYMKNCALVEELRLNIDKNLNILTGETGSGKSIIIDALGL
                     CLGDKYDRSFLRKGTDKGLVEAVFFSDNRYLKKILEENDISMEDDNLLVITRLIYSDG
                     KSTARVNGRTVKVSLLKEIASTLIDIHGQHQNQALFNKDTHLKFLDLFGENELEEFKI
                     AYKKVYHKYSEVKKALNCLTENKDEMQIQREIDLLRFQINEIEAANLNKNEYEDLLKQ
                     REVYRNSEKIYNNLNSSYSKLHNGEYNVIDLIGLASKELNDISKYDSVLSEYSDTVER
                     IMYELQDISGEIRNYKDNIDFEPYELEQIELRIDEINNLRRKYGDSIDDIFEYYGKIK
                     DRLDEILNRDERVEQLRSKLMNIEEDLKIKASKLTKARIEVATTLEKILLDELKSLNM
                     KNVMFKVNFEKGPFTLDGVDDIEFMISFNLGEDIKPIYKVASGGEMSRFMLAFKTILA
                     DIDDIDTLVFDEIDTGISGIAAQIVGEKLSDIAKKKQIICITHLPQIAANADTHYCIE
                     KDTSNNRTFTNVSKLNESQRKNEIARLIAGNNITEKTIEHASEIIELAKKC"
     gene            33911..34777
                     /locus_tag="PC465_001197"
     CDS             33911..34777
                     /locus_tag="PC465_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648520.1"
                     /translation="MNKKDTMHLIFIIVIFILLWYIVVAVSEINKNIESCSNKLDYLS
                     QELMSTKSDISNTINEEMSKSYITKSIDLKVKKIEKKECIIDVDVQLSKLGKNGKVFF
                     MYKEDSDKWNETEMTKYGELSYACEIKINTGSEYDYKVVTSGAISESSDVQKFTKSDY
                     MPEQPIFNSGIRDNREYFIEIVENSNLFNHESEKSKNKAYDNIRLEKVDIIVNEGKKD
                     TIYKAKLAEGLDDGKTNNSNRNQVNYEVSFPKRDIDDIIYIKAKLTYNNGVEYTKDIT
                     EDITMGLQDLEK"
     gene            complement(34870..35361)
                     /locus_tag="PC465_001198"
     CDS             complement(34870..35361)
                     /locus_tag="PC465_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2648521.1"
                     /translation="MADKMAQNITLQFVEEKDLENLENVKLLFTEYSNSLNIDLCFQD
                     FNNELKTLPGKYKKPSGSLILAFVDENLAGCVALKKLEGKICELKRLYVRNQFRGLKI
                     GKILLEEIIEEAKKFGYTHMRLDTLPSMKSAQGLYEKFGFYDIEPYTYNPIEGARYME
                     LKL"
     gene            complement(35422..35862)
                     /locus_tag="PC465_001199"
     CDS             complement(35422..35862)
                     /locus_tag="PC465_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2648522.1"
                     /translation="MKLNVRIADINNWHDLVSLSVDKSQLDYIESNALSIAESKFITA
                     WVPVGIYDENSLIGFAMYGRLEDDRVWLDRFMIDSKYQGKGYGKASLDFLVNHLKNEY
                     NCDELYLSIFEDNKMAIKLYKDFGFEFNGELDYGGEKVMVLKSN"
     gene            36023..37081
                     /locus_tag="PC465_001200"
     CDS             36023..37081
                     /locus_tag="PC465_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HDF2648523.1"
                     /translation="MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFAI
                     KNHDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVDYIGGIQIGDNIVKIDNKRIKNSQ
                     DVSEILNKIKKSKVEVTFERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
                     PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLM
                     GNFSNNSELGISGNITENHNKEFNVANKEKQLIEVGRPQDVKIGDAVILFEDKNKNIT
                     SYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVF
                     RDNPKKGYGIFIDEMIKL"
     gene            37223..38047
                     /gene="spo0A"
                     /locus_tag="PC465_001201"
     CDS             37223..38047
                     /gene="spo0A"
                     /locus_tag="PC465_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="HDF2648524.1"
                     /translation="MGGFLVEKIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGI
                     EALDLVKKTQPDLLILDVIMPHLDGLGVIEKLNTMDIPKMPKIIVLSAVGQDKITQSA
                     INLGADYYIVKPFDFVVFINRIRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIE
                     TEITNIIHEIGVPAHIKGYLYLREAIKMVIDNVELLGAVTKELYPSIAKKFNTTPSRV
                     ERAIRHAIEVAWSRGKVDTINQLFGYTVHNTKGKPTNSEFIAMIADKLRLEHSMVK"
     gene            38460..39581
                     /locus_tag="PC465_001202"
     CDS             38460..39581
                     /locus_tag="PC465_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648525.1"
                     /translation="MRVEAPIKVDRKTKKLAKRVESGEIAVINHIDIDEVAANSLVEA
                     KIKLVINAAPSISGRYPNKGPGILTENNILIIDNVGEELFEELKEGETIEVVDGKIYR
                     KGKFLGAGEVLDKYEVSHQIKAAYENLAVELDRFIDNTIDYAKKEKGFILGEVEIPKV
                     KTNYANKHVLIVVRGQDYKEDLSTMLSYIEEVKPVLVGVDGGADALIEFGYTPDVIVG
                     DMDSVSDEALKKASEIVVHAYTDGRAPGLKRVEELGLDAVVFPAPGTSEDIAMLIAYE
                     YKAELIVAVGTHSNMIDFLEKGRKGMASTFLVRLKIGSKLIDAKGVNLLYRSKLKIKY
                     IWALIATALFPVLVVASLSPGVQQFIQLMQLKFRVLLQM"
     gene            39599..40474
                     /locus_tag="PC465_001203"
     CDS             39599..40474
                     /locus_tag="PC465_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter"
                     /protein_id="HDF2648526.1"
                     /translation="MHINMKYYIVTIGAIFIALGIGMLVGFNLNNNQQLSEQQANIIN
                     DLDDKFDILKEKNDKLDSDLASVNRDYEEAVNFINKNVDKILAGSLNGKSIGIISANE
                     NDDYTKNIEDIINKSNGSIAFNIILKENITNPEKLKEMSTKLGTDVKNANDAVNYIID
                     TLKKEDASDILTYLQELDVIKFNFIGDTYLKYDSVVIAGGNDAKDSTKQFEKIEKFVV
                     SKLKSENKYLVEVQNTGVKTSYVELYSKNKVATIDNIDEGIGSISLAILLQQGNIVGN
                     FGRLDTATSLLPSIK"
     gene            40498..41190
                     /locus_tag="PC465_001204"
     CDS             40498..41190
                     /locus_tag="PC465_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2648527.1"
                     /translation="MDSYISIIIPAYNEESRIKYTLESILDIKQINEIIVVDDGSIDN
                     TAKVVSELENEKIKFFKLDKNRGKGYALNYGIKLAMKNADIIGFLDGDLGSSAKEVEK
                     LIVPILNGEADVTIAKFPPAKRKGGLGFVKGLAKNSVFEMTGVELDATLSGQRIFKRE
                     VLEKFDEIPFGYGVEVGMTIDILKYGFKIKEVLVNMTHNETGRNLKGFIHRGKQYYHI
                     KKVLGQKKKEWR"
     gene            41198..42022
                     /locus_tag="PC465_001205"
     CDS             41198..42022
                     /locus_tag="PC465_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDF2648528.1"
                     /translation="MKDYILYTILLLTGLFGTYAVIPLFKNLLINGNVLRPNYKKDMI
                     PVSMGIVFLPMIVINGIILAFFTTEFKDLAYIFMFMFGMISMFFAGILDDVIGNRDVS
                     GLKGHFKSLFKGSLTTGGFKALFGGFVGLIVSVAISKDIIDIIVNTLIIALSTNLMNL
                     LDLRPGRAIKAYLFIMVIIFLTLTGFVQVLPLLIVPNVLAYFNYDLKARAMMGDTGSN
                     VLGISIGMLISFGYPFNIRLGWLIFVVIMHIFTEKYSLTKIIEKNKLLNFIDKLGR"
     gene            42027..43094
                     /locus_tag="PC465_001206"
     CDS             42027..43094
                     /locus_tag="PC465_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3866 family protein"
                     /protein_id="HDF2648529.1"
                     /translation="MISKRVGIVESIVSQTETLDDIRVNINGEIQRAYNYPKISGTIN
                     IGDEVVLNTTAVELSLGTGGYHFVITNLNNIESTLTEGGHIMKLRYTPLQIKVDSVEE
                     QESIYHDKFANFKGLEGLSVVVGTLHSMLTPFAASFKRNNPNKKLVYIMTDGASLPIY
                     LSKNVDTLKEKKLIDSTITIGNAFGGDYECINIYTALITAKEILKADAVFVSMGPGIA
                     GTGTKYGFTGIEQGSILDAVKKLEGRAIAIPRISFADKRERHQGISHHSMTVFKEIVN
                     VNVDIPITIYDDEKLNFIKEQINLNGLDKKHNIIYIDNNKTKEDLDYFNLKVKSMGRN
                     YEQDEAFFKAASTAAYYLMEV"
     gene            43096..43632
                     /locus_tag="PC465_001207"
     CDS             43096..43632
                     /locus_tag="PC465_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF2648530.1"
                     /translation="MVLEEKTISSDRVYTGKVITLKVDTVEIPGQGYQKRELVEVGGA
                     VGIVAITDDNKVVLVKQFRKPIEKPIFEIPAGKLEKNESPKECAERELKEETGYSAKN
                     IKLIHKFFTSAGFSNEIMFVYLATGLTPGENNLDADEFLDVYEIELEEAYNMVLKNDV
                     EDAKTSIGLLLVKDMFKN"
     gene            43700..44305
                     /locus_tag="PC465_001208"
     CDS             43700..44305
                     /locus_tag="PC465_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HDF2648531.1"
                     /translation="MRRTYRKNDFRELNRQIIIIGLLFMMSIVIGSYINKILPGSSNN
                     ILNNINPAVEYYNLNISIKDTVIQNLKSDAIFMGSIALLSLFVVTIPAVLVAFVLKGM
                     SIGYTINSCILALKFKSIKMILIILFKNLIIIPCAIILALISLSYFKEMVYEFKKKNR
                     KNMQFLIKRYILNIIIIIALSLGLQLILNTASIGIIKFLAK"
     gene            44317..45231
                     /locus_tag="PC465_001209"
     CDS             44317..45231
                     /locus_tag="PC465_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2648532.1"
                     /translation="MDIIEGYIDYIKDKKKLSENTVASYFMDIKKYMEYINQKSIKLV
                     DIVENDIISYLIKLEKDNVSIATIARMISSIKSFHDYLFLNHICANNPAKDIKKPKIK
                     KENINILTEEEIERLLNFPKLTTPKLIRDKAIFEVLYGTGIKVSELVEMNIEDIDLDI
                     DYIYCNSCCKNQRVIPLCDITKLYLEKYLKEARPKMAVEGEKSLFVSSLGQRFTRQGL
                     WKVIKKYSNLANIDKNINPTMLRHSFAIHLLNEGANIAVVSKILGNVNLSSLQVYLNH
                     IDKNVRREIKEKHPRNDVDVELQKAEAK"
     gene            45273..46445
                     /locus_tag="PC465_001210"
     CDS             45273..46445
                     /locus_tag="PC465_001210"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HDF2648533.1"
                     /translation="MSRVIWIVIDSVGIGALPDAEKFGDSKDVSTLGNIFKEYPDIQI
                     PNMRNLGIGNIDGIDFFESIKEPIGCFGKCKEMSQGKDTTTGHWEMTGIIVDKPFKTF
                     EHGFSKEIIEEFEKKTGRKVVGNKPASGTVIIDEYGEHQIKTGDVIVYTSADSVFQIA
                     ANEEVIPLEELYNMCKIAREIMMGDNAVARVIARPFIGKKKGEFVRTSNRRDYSLDPF
                     EPTVLDNIKESGLDVLAVGKIEDIFNGKGITDAIHTKSNMDGVDETLNYMKQDNKGLI
                     YSNLVDFDSKYGHRRDPEGYKKALEEFDSRLPEIMANMREDDILIINADHGNDPTYKG
                     TDHTREYIPVMIYGNKIKKGFNLGVKDTFADIGATVADILNVKLPKHGSSFKEDLF"
     gene            46492..47304
                     /locus_tag="PC465_001211"
     CDS             46492..47304
                     /locus_tag="PC465_001211"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDF2648534.1"
                     /translation="MFEKIAQSSKFINSKSNIKPKIGLILGSGLGDLANDIEDPVTIK
                     YSEIPNFPVSTVAGHAGQLVIGKLEGKEVIAMQGRFHYYEGYSQKEATFPVRVMKELG
                     VEILIVTNAAGGVNKEFKAGDLMLIRDHINFSGSNPLVGKNDDRFGARFPDMSDAYSS
                     KYVDVVKNCAKECNIDVKEGVYMFFSGPNYETPAEVRMAQILGADAVGMSTVPEVIVA
                     SHSNIGVIGISCITNMAAGILNQPLSHEEVIETTQKVKSEFMNLVKTTVKNL"
     gene            47508..48833
                     /locus_tag="PC465_001212"
     CDS             47508..48833
                     /locus_tag="PC465_001212"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HDF2648535.1"
                     /translation="MRMYDIIKKKRDNLELSKKEINYFIENYSKGDTPDYQASALLMS
                     IYLNKMNKQETVHLTEAMMNSGDMINLSEIDGIKVDKHSTGGVGDKTTIALIPLVASC
                     GAPVAKMSGRGLGHTGGTIDKLESIPGFSTEMEISKFIDSVNKSKIAVCGQSAKVAIA
                     DKKIYALRDVTATVDNISLISSSVMSKKLASGADAIVLDVKTGDGAFMKTLEESFELA
                     KSMVDIGTGMNRDTIGIVTDMDEPLGFAVGNSLEVIEAIETLKGNGPKDLVELCEVLG
                     AYMLVLSKVAHDFEDGVEKIRESIKSGTAIQKLKEFIENQGGNKDVVDDYSLFKKSKY
                     KYPVKSTKSGYISKIKAEDVGVSAMILGAGRETKDDILDLSAGIILEKKVGDYVNEGE
                     VLAYMYYNDEQKLSLAKGRFIDSYSIVDSKIEKNKLIYGIVTKEEIKKF"
     gene            49036..50115
                     /gene="mltG"
                     /locus_tag="PC465_001213"
     CDS             49036..50115
                     /gene="mltG"
                     /locus_tag="PC465_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HDF2648536.1"
                     /translation="MNFKENRLKIAVLIIVILIILAGIFVFIQIGPYDKNNKKDVIID
                     VPSGASVGKISDILYENKLIKNELLFKLLVKVSNKAPSIKSGTYLLNQSYSNNDIISL
                     LVSGKIYQDGIKVTIPEGATSKEIIAMLVSKNLGDKATFENLIKKPQEFYDKFPYLKE
                     DGITSLEGFLYPETYYFNSKKQSEEDILSEMLKVFDSKYTDKFKKKQKELNMTLQEVM
                     EMASIIEKEAVLDKDRPIIASVFYNRLKVGMPLQSDATIQYIFEERKKIVTYDDLKID
                     SPYNSYKNKGLPPTPISNPGIKSIEAALYPEKTDYLYFVAKIDGGNNYSTNYQDHLKY
                     VKEYKEARDKQSKDTKATNKENTKK"
     gene            50287..50961
                     /locus_tag="PC465_001214"
     CDS             50287..50961
                     /locus_tag="PC465_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HDF2648537.1"
                     /translation="MSNIVNDLVEDYIRVTLKEKEGFLKDLEIYAEENSVPIIHKEVS
                     DLLKVLLKVQKPKRILEVGCAIGYSSIFFATIIGKDADIITVERNEKMIEKAKENIKL
                     AGFDNNITILEGDAEEKLSQVQGEFDLIFIDAAKGQYKLFFDLVIDKLKDGGLLVSDN
                     ILYKGMVAHDDFVVRRKKTIVKRMRNYLDYICNCDYLSTSLVPIGDGVALSYKESKRG
                     DVDGIK"
     gene            50948..52195
                     /locus_tag="PC465_001215"
     CDS             50948..52195
                     /locus_tag="PC465_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDF2648538.1"
                     /translation="MELNKVELLAPAGDLERLKIAITYGADAVYIGGEIFGMRSAAKN
                     FSKEDMAEGVAFAHERGKKVFVTVNIIPHNEDFLQLEDYLLELEEIGIDAVIIADPGV
                     LSVIKKVIPNMEIHLSTQANTTNYLSANFWYEHGIKRVVVARELSFDEISEIRAKTPL
                     DMDIEAFMHGAMCISYSGRCLISNYMTGRDANKGSCAQSCRWQYHLVEEKRPGEYFPI
                     YEDERGTFFFNSKDLCMIEYIPELIKSGITSLKIEGRMKTAYYVATVVRAYRMAIDEF
                     YRDPENWKFNPMWMEELKKGSHRHFTSGFYLNKPTTEDQNYQSASYVRNYDFIGIVRE
                     TEDEDGLIVVEQRNKMCVGDEIEVMGPYKETMFTKIEEMYNEEGEAIESAPHPRQIVK
                     LKLSVKVGKDYMLRKVIEEKVEE"
     gene            52267..53931
                     /locus_tag="PC465_001216"
     CDS             52267..53931
                     /locus_tag="PC465_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HDF2648539.1"
                     /translation="MSKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDK
                     YKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKSQILIVEKEKLNNNYKILELIKK
                     ATKMNDLDIYKAVQEQLTRPIIQIQTKNIDKSMKKELEKNGIMVEEKTMRYAKDGLLS
                     HTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKTVD
                     NKDKDRHLKTTIDYNIQKKLEQILNKEENPTAAIISEASTGEILAMCSRPNFDQNDIS
                     KSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYNCTGKTKVGNTNE
                     ILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGLDE
                     EKIREAPKNISIRNLAIGQENIEFTPLQINQMTQIIANNGTFKPLYLYKSLVDNNMNT
                     IKTYKSSKKEELISPYVCTQVKEYMKSVSRTGTAKDLKDIEGGCGVKTGTAQSSLNKK
                     AIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIK"
     gene            complement(54028..54669)
                     /gene="sigK"
                     /locus_tag="PC465_001217"
     CDS             complement(54028..54669)
                     /gene="sigK"
                     /locus_tag="PC465_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigK"
                     /protein_id="HDF2648540.1"
                     /translation="MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVA
                     YIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSN
                     KKNKTQVSLQDPIGTDKEGNEISLLDILGTEANYVLDEVELKVQVGKLYEQLNKILTP
                     REREIVQLRYGLTPYGYKTQREIAQKLDISRSYVSRIEKKALKKLEKELVQES"
     gene            55236..55598
                     /locus_tag="PC465_001218"
     CDS             55236..55598
                     /locus_tag="PC465_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648541.1"
                     /translation="MKIRKSGFISIECIISIAILYVAVYLVSTSLYNCYSFISRNISD
                     REMLSTAKKYIEDEKYRIQNSKYELIEDKIEKNYINGYEINSRIEQILDYYQCYEINI
                     EIKNEFKKLRFNSYVTRK"
     gene            55582..56298
                     /locus_tag="PC465_001219"
     CDS             55582..56298
                     /locus_tag="PC465_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648542.1"
                     /translation="MLLENKGSILIITLIIFSIISTVCIMCIGLIYTHNNMFELGYKD
                     IQLKEISLSGIEISVSNVLSCVEEAIDVSNNEDEFREYFLGNNMIECIKKIKDTSYSS
                     LEELSLKVENNTIYDRGDFFEFDIESNVREKEFLKAIKVRVKIKNPWIGIDIEDYMDK
                     SNNNKIDDKTFNNYKASENNEILNQFKNESENIRNQEVGGFTEEDEEYEEELKQNIIE
                     NIKKNFDEKNLVQVYKYRGV"
     gene            56318..56737
                     /locus_tag="PC465_001220"
     CDS             56318..56737
                     /locus_tag="PC465_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648543.1"
                     /translation="MTVIELIVSISIILLIVTLSFPKDNLENHKINLFARQLCSDIRY
                     VRRINMFSNYNTYIYYINQGKHEGYVLRKDGKNIKSIMLPKNAKIARSIEIIKFKSDG
                     SPQKASTIEIYNNRLRKTITITPVSGRVLLKEGKYET"
     gene            56727..57251
                     /locus_tag="PC465_001221"
     CDS             56727..57251
                     /locus_tag="PC465_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648544.1"
                     /translation="MKHKYGYLLLESVVSLSSMVIIILVLYSIFLSTINLKLKVEDKI
                     ELQQQSLEIIKSMEGIIGNSMGIMNISNYEETFKKTTSIKCRYVDENNNEEGISNKEI
                     ILNERRNKLFVNSLNGESSQAGGYEIGDYVDEMYVSITNNGQYVNIKLKLSKRSQKYE
                     TDFKIKVWNFSESI"
     gene            57563..58120
                     /gene="efp"
                     /locus_tag="PC465_001222"
     CDS             57563..58120
                     /gene="efp"
                     /locus_tag="PC465_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HDF2648545.1"
                     /translation="MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNL
                     KTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYEQVEDAI
                     KFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVV
                     QVPLFINTGDKVKIDTRTGEYLSRV"
     gene            58212..58667
                     /locus_tag="PC465_001223"
     CDS             58212..58667
                     /locus_tag="PC465_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2648546.1"
                     /translation="MKHLYEEVAYLKGLAEGLEISAESKEGKMIHKIVDALEVFADAI
                     VTLDEEQEELQDFVESIDEDLADLEEDIADMEEDLYEEDDDEDDEDFSYIEMECPNCG
                     ELVEIDEDLLYDDEVDVVCPDCKAVILSSEDDCDDDCTCGGCSSCDDRE"
     gene            58830..59540
                     /locus_tag="PC465_001224"
     CDS             58830..59540
                     /locus_tag="PC465_001224"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HDF2648547.1"
                     /translation="MKISKKLLDNIQRFENVINYKFKNKEYILEALTHSSYSNENKKY
                     NFNERLEFLGDSVLGIVISDYLFNEEANLPEGELTKLRANIVCEDSLSEVANDINLGI
                     HMLLGRGEEATGGRHRTSILADAFEAVIAAIYLDGGFESARQFILHHMENIIYDSRKG
                     NIFRDYKTHLQEVLQGNGENNIWYRLIEEKGPDHNKRFVMEVGINDDVLGIGEGKSKK
                     EAEQLAAKIALKKKLWEK"
     gene            59594..60664
                     /locus_tag="PC465_001225"
     CDS             59594..60664
                     /locus_tag="PC465_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2648548.1"
                     /translation="MKKRIIPIFVPHKGCPHDCIFCNQKKITGVSTDVTSEDARNIIE
                     ECLETIDKDADVEIAFFGGSFTAIDIDIQKSLLSVAKEYVEKGLVKDIRMSTRPDCID
                     EDILSMLKEYKTSIIELGVQSLDEKVLLDSIRGHQSEIVYKSSKMIKNSGIKLGLQMM
                     IGLPADTEEKCIFTAKKFVELKPDCVRVYPTLVVKDTGLEKLMEQNKYNPFTLEESVN
                     IVKKVLVLFYVNNINVIRVGLQATDDIQIGKAVLAGPYHPAFRELVEADMIKDYLEFV
                     IFQNKNIKQMLVKSNKKNISKIIGNKKTNVKYMEEKFGVLLKTQESDLDINQLEIVLD
                     GKSLISANMRDIHRKLYDIYDL"
     gene            60692..64246
                     /gene="smc"
                     /locus_tag="PC465_001226"
     CDS             60692..64246
                     /gene="smc"
                     /locus_tag="PC465_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HDF2648549.1"
                     /translation="MYLKRLELKGFKSFPVKTDIIFKEGITAIVGPNGSGKSNISDAV
                     RWVLGEQSIKSLRGDKLEDVIFAGTDTKKPMNYCEVALTIDNSENQLELDFTEVTIRR
                     RAYRNGESEFFLNNKSCRLKDIKEVFLDTGIGKDGYSIIEQGKVDEILSNNPLSRRKV
                     FDEACGISKYRYKKQEAERNLSNTKENLERIDDVYIEIENQLKPLFNQQTKAKKYLEI
                     SEKLKTLEVNSFIREIEGIEKELSEVNEHRNVIEKELNEKEEQKNVVEKKQEDINKEV
                     EVLQDVIEKSVDYINSIKGVISKKESQINLIKERIRNFTNEISRKNLEIKDIKEKLNE
                     NKQYIKELESNKLSGSEELSTLQENIKVLEGSKDKQKIKLESLNNEIELLKESIIDIL
                     NKKQEFSNKLSTLNANKENMNIRDENINSEITELNKNIEIKSSELDTINKEFNMQNEN
                     LKNVNNRHKELSINLQDSISEHNKLEDEIQKSKYNLNGYNSKLNVYIDMENHYEGFNR
                     GVKEVLKNKNLKGVHGALGQIINVPEKYEKSIEAALGAYMQNIITDNEFSAKSAINYL
                     KQNNLGRVTFLPLNIIKSNKISLGNLKANTKFIGIASDLITFDEKYRNIIENILGRTI
                     LINNIDEGIKFAKETGHRFKIVTLDGEILNPGGSLTGGSLKTNGNILSRKRYINEYTE
                     KISNIKNQISHLELKRESLDKDVKNIKNEIDSHESKIKDLEKSIIIKSTSIKNVESEI
                     ESLKGSITKLENEKNDLNSNLNYTLEKSDDVRKDMEELDDLYNKNKEKIDALNEEIKR
                     YNDLYDKEKSEFDELNLSLVKKTEVYNSIVRDIKRISGENCELEEKNKQLEESLNYEE
                     HEIIKLQDSILTEEKEKENLTKQLGDSNRNLETRKIAKDDLKNSFDEINKELKTIDRQ
                     HIELKESLFKVGGRLERLKTSQDTYINKLFEQYDMTLVQALEIKDEDLDIDRKFLESL
                     KREIRSLGNINIDSIKEYEEIKERYDFYSEQKQDLEESMEEIEKLIHTLEENMKSEFE
                     IKFEEISKNFKYVYKRLFGGGCGELTILDKENLLESDILITAQPPGKKMKNLNLLSGG
                     EKALTAISILFAILITKPTPFCILDEIEAPLDDANIFRFGEFLKDLSKETQFISVTHR
                     RGTMEAADYIYGVTMQEKAISKVISLKLKEAQEITDII"
     gene            64273..65553
                     /gene="ftsY"
                     /locus_tag="PC465_001227"
     CDS             64273..65553
                     /gene="ftsY"
                     /locus_tag="PC465_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HDF2648550.1"
                     /translation="MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDNLENLEETIFSG
                     FEEEVIDKVEDVEEKNEESVNNEGTEEIENFEKIEVEMDSNGKEVENISNNDSQEEIV
                     EELENYDEIESKEIEDKEDKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELL
                     EDLEEILITADVGVNTTMDIIERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTL
                     DIEPAPCIILMVGVNGVGKTTTIGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWAN
                     RTNVDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHNKANLMNELGKVFKI
                     VDREFPEAKREVLLVVDATTGQNAVVQAKTFKEVADITGIVLTKLDGTAKGGVVLAVK
                     SEVDVPVKLIGVGESVEDLQDFNAKSFSDALFGN"
     gene            65656..66024
                     /locus_tag="PC465_001228"
     CDS             65656..66024
                     /locus_tag="PC465_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HDF2648551.1"
                     /translation="MNIEKMVEIGLLFEQYKELLTDKQKEIVALYYEEDYSLGEISEN
                     LNVSRQGVYDTLKRSEKILRDYEEKLHLVSKIQEQEKNIKIIKDKIIDIKEDLLHNKD
                     CANLIPKLENIEDVCREMIK"
     gene            66021..67373
                     /gene="ffh"
                     /locus_tag="PC465_001229"
     CDS             66021..67373
                     /gene="ffh"
                     /locus_tag="PC465_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HDF2648552.1"
                     /translation="MIFEGLSDKLQGAFSKLKSKGKLTEVDVKNAMREVKLALLEADV
                     NFKVVKDFIKKVQERCVGQEVMQSLTPAQHVIKIVNEELTSLMGDVQSKVMISSKPPT
                     ILMMVGLQGAGKTTTAGKLGGYFKKQGKKPLLVACDIYRPAAIKQLQVVGEKLDIPVF
                     NMGDKENPVNIAKAGLSHAIKNANDLVIIDTAGRLHIDEVLMDELKSIKSEVKPHEIL
                     LVVDSMTGQDAVNVAESFNEALGVDGVVLTKLDGDTRGGAALSIRAVTQKPIKFMGMG
                     EKLDDIEPFHPDRMASRILGMGDVLSLIEKAQENIDLEKAKELEQKIKKQELDFEDFL
                     QQMEQIQNMGPLDKILGMIPGMGNVKDQLGDVDLNGKEMKRTKAIIQSMTTYERRNPG
                     VLNASRKKRIAKGSGTSVQDVNRLIKQLNEMKKMMKMFAGSQKSMKKRGGLGGLPFFK
                     "
     gene            67411..67683
                     /gene="rpsP"
                     /locus_tag="PC465_001230"
     CDS             67411..67683
                     /gene="rpsP"
                     /locus_tag="PC465_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HDF2648553.1"
                     /translation="MAVKIRLKRMGANKKPFYRIVVADSRAPRDGKFIEEIGYYNPIS
                     EPKQVRINDEKAIKWLATGAQPTEVVKKLLVKNGVIEKFEASKQAK"
     gene            67748..67975
                     /locus_tag="PC465_001231"
     CDS             67748..67975
                     /locus_tag="PC465_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HDF2648554.1"
                     /translation="MKELVVDIAKALVDNPDSVVVEEFEDNDGIVLKLTVAQEDMGKV
                     IGKQGRIAKAIRTVVRSVANRENIKVSLEIV"
     gene            68083..68598
                     /gene="rimM"
                     /locus_tag="PC465_001232"
     CDS             68083..68598
                     /gene="rimM"
                     /locus_tag="PC465_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HDF2648555.1"
                     /translation="MKEKLTHFKVGQIVNTQGLKGEVRVYPLTDDIERFDELKDFYLG
                     KDLNNKLAVEKVRYKGSMVIMKIKGIDSIEKAEKLKNKFMYVAREDSRELEEGEFFIA
                     DMIGMEVLTVDGKYVGILEDVLQYSANDVYVVKGEEDKEFMIPAIKKFVPTIDIDERK
                     MIIDPIKGMID"
     gene            68607..69302
                     /gene="trmD"
                     /locus_tag="PC465_001233"
     CDS             68607..69302
                     /gene="trmD"
                     /locus_tag="PC465_001233"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HDF2648556.1"
                     /translation="MRFHIMTLFPEIFNSYMDESIMKRAVEKGIIEVHIYNIRDFSNN
                     KHKKVDDYPFGGGAGMVMTPQPIYDTYKHIITTHNINNPSVIYLTPKGKVYNQSMAKQ
                     MSLKEDIILLCGHYEGIDERIIDLIVTDEISIGDYVLTGGELPALIMIDSISRLIPGV
                     LNQEESFEEESFKDNLLEYPHYTRPRDFEGLKVPEVLLSGNHKKIDEWRREESIRITK
                     ERRFDLYKKSNEK"
     gene            69487..69837
                     /gene="rplS"
                     /locus_tag="PC465_001234"
     CDS             69487..69837
                     /gene="rplS"
                     /locus_tag="PC465_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HDF2648557.1"
                     /translation="MNEMLRAIEQEQLKNEVPNFGPGDTVKVHVRIIEGKRERIQVFE
                     GVVLKRQGGGARETFTVRKMSFNVGVERTFPVHSPKIEKIEVTRKGKVRRAKLNYLRG
                     RVGKAAKIKEARNK"
     gene            70158..71054
                     /gene="ylqF"
                     /locus_tag="PC465_001235"
     CDS             70158..71054
                     /gene="ylqF"
                     /locus_tag="PC465_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HDF2648558.1"
                     /translation="MSNEYEEYLMNDNLHINWYPGHMKKTKELVKNNLKLIDVVIELL
                     DARIPFSSKNPDIDRLVGDKPRVVVLNKSDMADRDKLNQWIEYYKKINIKAIPVDTIK
                     GVGINKIIEECKNVTREKMSSLKDKGRKERAIRIMIVGVPNVGKSSLINKLTGRKSTQ
                     TGDKPGVTKGKQWVRLKGNLELLDTPGILWPKFEDQEVALNLAFSRAIKDEILDTETL
                     ALRLIEKLMKIEPEKLKARYKLDCLGETPIETMDMIGHKRGFITGKKELDYTRIATTV
                     LNEFRDGKIGNITLEVPENVKR"
     gene            71443..72735
                     /gene="brnQ"
                     /locus_tag="PC465_001236"
     CDS             71443..72735
                     /gene="brnQ"
                     /locus_tag="PC465_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDF2648559.1"
                     /translation="MGKTKDVIVFGFALFAMFFGAGNLIFPPYLGIITGPEWLIAFLG
                     FTFADAGLALLAVMATAKFDGNVVEMFKRCGMKLGILIGCADILCIGPFLAIPRTGAT
                     TYEMGIMPLFGTSIPVLLFCILFFAISYVLTIRPSKVVDIVGQFLTPALLIALAFIII
                     KGIISPLGDIVDKPMIPNVFAEGIGQGYQTMDAFAAIALASVLIVSLNDKGYSTISDK
                     LKMIGKAGVLACGGLALVYGGLCFLGATVSTMYGTDAVQSQVIVNITEGLLGNVGKAI
                     LAVVVSLACLTTSIGLTSATGQYFSRLTKGKLSYEKIVLAVSVFSAVVASFGVGTIIK
                     IASPILSIVYPPSIVLIILAFFNEKIKNDNVYKGAVYMSLLVSILTVISSYGVAVPVV
                     NSLPLNSLGFNWVVPVIIAGIIGNFIPSKSQSNTLGTN"
BASE COUNT        29858 a         7257 c        13569 g        22159 t
ORIGIN      
        1 aaaagataga gttttattta gacatttatt acaaatcaaa atttattaca tattatttat
       61 aaaaaaatct aaggaggaaa taataatgaa aatattagta ttaaactgtg ggagttcttc
      121 attaaaatat caattaatag atatgaataa tgaagaagtt ttatgtatag gattggttga
      181 aagaatagga atagaaggtt ctatattaaa acatgaaaaa gcaggtagag atgataaata
      241 cgttgttgaa caaccaatga aggaccacaa agatgcaata gcattagttt tagaagctgt
      301 tgctcatcca gaatttggtg cagttaaaga aatgaaagaa atagatgcag taggacatag
      361 agttgtacat gctggagaaa aatttgcaac ttcagtagta ataactccag aagtagaaga
      421 agctttaaaa gaatgtatag atttagctcc acttcataat ccagcaaaca taatgggaat
      481 agatgcttgt aaagctatac ttccagatgt accaatggta ggtgtatttg atactgcttt
      541 ccatcaaaca atgcctaaat cttcatactt atatggttta cctcatgagc tatatactaa
      601 atatggggta agaagatatg gattccacgg aacttctcat aattatgtat ctcaaagagc
      661 agcagagata ctaggaaaag atataaaaga tttaaaaata gtaacttgtc acttaggaaa
      721 tggtgcttct atagctgctg ttgatggtgg aaaatgtgta gatacatcta tgggattcac
      781 tccattagaa ggattaataa tgggaactag atgtggagat atagacccag ctatattacc
      841 attcttaatg agaaaagaag gtttagatgc tgatggattg gataaattaa tgaataaaga
      901 atctggagta tatggaatga ctggaatttc tagtgacttc agagatatag aagatgcagc
      961 taaaaatgga gacgaaagag ctcaagctac attagaagcg tatgttaaaa aagtacaaaa
     1021 atatataggc gcttatgctg ctgaaatgaa tggattggat gttgtagtat ttactgcagg
     1081 cgttggtgaa aatggaaagg ctataagagc agatattgct tctaacatgg agtttttagg
     1141 aatgaaatta gataaagaag ctaatgatgt tagaggaaaa gaaacagtaa tatctactgc
     1201 tgattctaaa gtaaaaatgc ttttaatacc aactaatgaa gaattaatga tagctagaga
     1261 tacattaaga ttggtaaaat aattaaatta aacctatgcc tatcaagtaa aaatacttga
     1321 caaacaaatg ctagatttgt ataataaatt tggtgatatg ttgaggtgaa cttaatgaaa
     1381 gttagcatag aaaaaataaa tagaaaagaa actgacaaaa tagacttgaa tttttgtgaa
     1441 aaaattgata ctattagtta ttgtgatgag atttacaaat tagtatcacc tgtaaattta
     1501 aaagggaaag tgtcaaagac taataaaggt ttgtatctag atatagatgt caattttaca
     1561 attgttgaca attgttcaag atgtcttaaa gaagtagaaa taccactaga gtattctata
     1621 caaggttttt tagtaaaaga agaagattat gatgaagatg agtttgagga atttgatcct
     1681 tttatattcg atggtgaaga aatcgacctt attgatataa tagaacagac attagatttt
     1741 aatgtacctc ataaagttct ttgtagtgaa aactgtaaag gtctttgtca agtatgcggg
     1801 gcaaacttaa atgaagaaga gtgttcttgc agtgaaatta caaacgatga ggaatacata
     1861 gatcctcgtt ttgctaaatt aaaagattta tttaattaaa ttttgactaa ggaggtggcg
     1921 taaatggcag taccaaagcg taaaacgtct aaatcaaaca caaaaatgag aagagcagct
     1981 aactcaaaga tggaagcaac aggatttgta agttgcccac aatgtcatga gccaaaatta
     2041 ccacatagag tgtgtccaga ctgtggatat tataaaggta aagaagttgt gtctaagtaa
     2101 tagcttctaa aaagcatgta gagtatactc tacatgtttt ttttgtacat ataaaaaaat
     2161 aagatgattt actagagaaa ataagtggat tttatgcata ttaaaaaata gaaaaataat
     2221 aatataagta ttgaaaattt ttgtgtgtta ctatatacta ctattagtag ctggtactaa
     2281 ttacagctat aaaatttgga gggaacatga aaaagaaaag taaagcccaa agacaaaaag
     2341 agcttataga tatgctaaag acagatcctt tttatactga tgaagaatta tcaagtctgt
     2401 ttgatgtaag tatacagacc ataagattag atagaatgag tctaaacata ccagagctaa
     2461 gagaaagagt caaatcaata gcagaaactc agagttcaaa agtaaagact ttaggagtaa
     2521 aggaaattac aggagaaatc attgatttat ctgtagggcg attaggtata tctatgttag
     2581 aagttacaca ggacatgatt tactctaaga ctaatacttt aaaagatacg tatatttttt
     2641 ctctagcaga ttcattggca atggctataa tagatgcacc taaggttatt atgagagttg
     2701 caaatgtaaa aagttttaag ttgatagaac aacaagatag acttatagca aaagcagaag
     2761 tgtatagaaa tatagataaa aagcattatg taaaagttgt tatcaacaat aaagcccaag
     2821 agcaaatatt tagaggaaag tttatctttg aagaattaga ttaggaggga aattatgaaa
     2881 atagtaattg atggaatggg tggagataat gcacctaaat ctaatgtaga aggcgcagta
     2941 aatgctataa aagaatatca ggttgattta ataatcacag gagataaaga tttacttgaa
     3001 aaggaatttt caaattatga atttgataga aataaattag agatagttca tactactgag
     3061 attatagaaa acgaagataa accagtaaag gctataagaa gtaaaaaaga ttcatctatg
     3121 gtagtagcat taaatcttgt aaaagaagga aaggcagatg ctataatatc agctggaaat
     3181 acaggagcct tacttgctgg tggattattt gttgttggta gaataaaagg aatcgataga
     3241 ccttgcttat gttcagcaat accaaatgta aagcgaggaa tgacacttat agcagactgt
     3301 ggcgcaaatg cagattgtaa acctaagaat ctagttgaat ttgcagctat gagtaatatt
     3361 tattcaagaa aagttttagg tcttgaaaat cctaaggtag cattagcaaa tgttggacta
     3421 gaagaaggca aaggcaatga tttagtcaaa aggtcatatg aagaaattaa aaaattagat
     3481 ttaaatttta tagggaatgt agaagctaga gaagttataa atgcatacac agatataatc
     3541 atatgtgatg gatttacagg taatatatta cttaaatctg ctgaaggtgt agcactttca
     3601 gttatgagtc ttataaagga aacttttatg gccagtacaa aaagtaaaat aggagcatta
     3661 cttataaagg atgatttaag aaaattaaaa agttttatag attattctga gtatggggga
     3721 gctccacttt taggtctaaa tggaggagtt ataaaagctc atggtagttc tgatgctaaa
     3781 gctataaaaa atgctataaa tcaaggaata aaattttcaa agggaaaagt cgttgaagat
     3841 attaaccaat ttataagcaa atacaatgaa gaaaataaaa ataacgaaga tgaataaact
     3901 cgttttggag gtttaatata taatgaatac aaaggctgga atattaggag taggaagtta
     3961 tctacctgag caatcatatg ataattttca cttcgaaaaa ataatggata catcagatga
     4021 gtggataagt actagaactg gtattaagga aagaagattt gccaaagagt ctgaagcaac
     4081 ttctgactta gcatctaaag ctgccttaaa agctatagaa tgtgcaaagt taaacgtaga
     4141 ggatatagag ctgattatat tagctacaat tactcctgat atgtctttgc cttcaactgc
     4201 atgtatagta caagatgcaa taggagcagt gaatgctact gcatttgata tatcagcagc
     4261 ttgttctgga tttgtatatg gagtaactat tgcaaagcaa tttgtggaaa caggttgcta
     4321 taaaaatgtg cttgtaatag gagcagaaac ttgttctaag tttttaaatt atgatgatag
     4381 aacaacagca gtattgtttg gagatggagc tggagcagct gttattggcc ctgtaaatga
     4441 gggtggaata ctgtctacac atatgggctc tgatggtaaa ggaaaagatt gtttaaaagt
     4501 acctgctgga ggttcaagac ttaaggcaag taaagagact gtagaagcta atctacatac
     4561 aatagaaatg gcaggtagtg atgtgtttaa atttgcagtt agaaagatgg cagaaacttc
     4621 tttaagagct cttgaaaaag caaatctaaa tacaactgat atagactact tagtgccaca
     4681 tcaagctaat ataagaatca tacaagcttc ttctaagaga ttagagcttg atatgaaaaa
     4741 agtttatgta aatatagaca aatatggaaa tatgtctgct gcatctatac cagtagcatt
     4801 agatgaagct tatagagaag gtaaaattaa aaagggtgat aatgtagttt tagttggctt
     4861 tggtggaggt ctaacttggg gggcttcagt tgtcaagtgg actttatagt ataaaatatc
     4921 taaaatgatt taattaacaa aattaaactt atacacaaaa taaagttgat taataataaa
     4981 aagtttactt ttatgatttc aaatgaagga gaattgtatg aataaaattt gcaaaatatt
     5041 aaatataaaa tacccagtta tccaaggggg aatggcatgg gtagctactg catcattagc
     5101 aagtgctgta tctaatgcag gaggacttgg cataatagca gcaggaaacg caccaaaaga
     5161 agctataaag aaagaaattg ttgagtgtaa aaaattaaca gataaacctt ttggagtaaa
     5221 tgtaatgctt atgtcgccat ttgttgatga tataattgat ttgattatag aagaaaaagt
     5281 tcaagttatt actactggtg ctggaaatcc tgcaaagtat atggatagat taaaggaagc
     5341 tggaacaaag gttattcctg tagtacctac aatagctttg gcacaaagaa tggaaaagct
     5401 aggagctaca gcagtaatag cagaaggtac tgaaggtgga ggacatatag gagaacttac
     5461 tactatggtc ttagttccac aagttgctga tgctgtaaac atacctgtaa tagctgctgg
     5521 aggaattgta gatggtagag gaattgcagc atcatttgca ttaggtgcca gtgcagttca
     5581 agtaggaact agatttattt gcagtgaaga gtgttctgtc cattcaaact ataaaaactt
     5641 agtactaaaa gcaaaagata gagatgcaat tgtaacagga agaagtactg gtcatccagt
     5701 aagaacatta aaaaataaac tatcaaaaga atttttaaag atggaacaaa atggagctac
     5761 tcctgaagaa ctggataaaa aaggtacagg agctttaaga tttgcaacag tagatggaga
     5821 catagaaaaa ggttcattta tggcaggtca aagtgctgct atggtaaaag aaataacacc
     5881 ttgtaaggaa attatagagg ctatggtaaa tcaagcaaga gagattatgc cagcaataga
     5941 actgtaaatc aggaggagca agatgggaaa agttgcacta gtattccctg gtcaaggagc
     6001 tcaatatgta ggtatggcca aggatttata tgaaaataat gctgttgcta aaagtgtaat
     6061 agatgaggct agtgatgcct taaatatgga tttaaaaaac cttatgttta atggaaatga
     6121 agaagaactt tctaaaactg aaaacactca acctgccatg gttacacata gtgtagcagt
     6181 attaaaagcg gtacaagctc aaatagattt aaaatataat gcatgcttag gattatcctt
     6241 aggagagtat agtgcgttgg ttgcagcaga tgcaattgac tttaaagatg ctgtatgttt
     6301 agttaaaaaa agaggtaagt ttatgcagga aacagttcca gcaggtgttg gagctatggc
     6361 agcagtttta ggtttagata gaaatgtact tgaaaatgtg gttaaagata tacaaggagg
     6421 tattgtagaa gtagcaaatt acaattctcc tggacaaata gttatatctg gtgaaaatga
     6481 aaagatagaa gaagcaatgg taaaatgcaa agaagcagga gcaaaaaggg cagttaaatt
     6541 aaatgtaagt ggaccttttc actcatcaat gttaaaagaa gctggtgtaa aattggccag
     6601 tgaattagaa aaagttaaca taactaaacc taaagttgat gtggtggcaa atgtaaatgc
     6661 agattactat aaaaacgaag gtaaagacct gcttataaaa caagtaagtt catctgttct
     6721 ttgggaagat tctatagaaa gacttttaaa tgatggatat gatactttta tagaaatggg
     6781 acctggaaaa actttaaaag catttattaa gaagatagct tccaataaaa aagcaaatgt
     6841 caatatttat aatatagatg gtatagattc tcttaatgaa tttgtacaaa attatagaaa
     6901 tggagagata taatgataaa tcttacagga caagtagcag ttgttactgg tggctctagg
     6961 ggtataggaa aagaaatagc aaaaaaacta gcatcttttg gagctgatgt agtaatcaat
     7021 tatacttcta aagaagatga agcactaaaa actaaaaatg aaatagaaag tatgggggta
     7081 aagtgtacct ctataaaatg tgatgtatct aaatttgatg aagtgaatca aatgatagat
     7141 tctgttgtaa gcgaatttgg aaaaattgat atattggtta ataatgcagg cataactaaa
     7201 gatggtctgc ttatgagaat gaaagaagaa gattttgata gagttataga tataaactta
     7261 aaaggtgtct ttaattgtac aaaagcagtt actaaaccta tgatgaaaaa gaagtatgga
     7321 agaataataa atatgacttc agtagttgga attatgggta atgcagggca aactaattat
     7381 tgtgcatcaa aagcaggtgt aattggattt acaaaagctt ctgcaagaga gttagcatca
     7441 agaaacataa atataaatgc agtagcacct ggatttatag aaacagatat gactaaagta
     7501 ctaagtgatg atgtaaaaga atcaacacta gcaaacatac caaagaaatc ttatggtaaa
     7561 ccagaagatg tagccaatgc cgtagcattt ttagttagtg acatgtcaag ttatataaca
     7621 ggacaagtaa taaatgtaga tggtggaatg gtaatgcaat aataatttaa aaagtagaga
     7681 aatctattaa aataaaaaat tttaggaggt acacaatgtt taataaagtt gtagaaataa
     7741 taatagagca attaggagta gaagataaag aaataactat ggaaacatca ttaatgaagg
     7801 atttagaagc agattcatta gatgcagtag aaataataat ggcacttgaa gatgaatttg
     7861 gtatagaaat accagataca gaagcagaaa acttcaaatc tataggagat atagttaagt
     7921 atatagaagc taataaatag tcgagcttta aaaaagtgga ggtatccgat gaataaaaga
     7981 gtagtaataa caggacttgg atgtgttacg ccgttgggaa caggaaaaga agagttctgg
     8041 agtaatataa aatctggagt atctggtata gataaaataa ctaattttga tgctagcaca
     8101 tatcaaactc agatagcagg agaagttaag aattttcatc cagaagaata tataagtaaa
     8161 aaagaattga agagattaga taaatttgct caatttgcaa tagtatctgc taaattagca
     8221 gttgaagatg caaatcttga tttagataaa gttgatagag aacgttttgg tgttataata
     8281 ggttctggaa taggtggagt tgaagccata gaaactcaac ataaaattct tttggaaaaa
     8341 ggaaataaaa gagtaagttc actttttgta cctatgatga taggaaatat ggcagctggt
     8401 caagtttcaa tatttttagg agcaaaaggg cctaacacta atgtatgtac agcttgtgca
     8461 tcaggaactc attcaatagg tgatgctttt aaggtaattc aaagaggtga tgcagacatt
     8521 atggtagcag ggggttctga agctgctgta acaggtcttg cttttgctgg attctgtaac
     8581 atgaaggcta tgtcaactag aaatgatgac cctaaaactg catcaagacc atttgataaa
     8641 gacagagatg gttttgtaat gggagaagga gcaggtattg ttatcttaga agacttagaa
     8701 catgctttag caagaggcgc taaaatatat gcagaagtag ttggatatgg tttaactgct
     8761 gatgcatacc atatgacaac tccagctgaa aatggagagg gagcagctag gtctatgaat
     8821 atggctttga aagatggaaa tgttccatta gaagaagtag attatataaa tgctcatgga
     8881 acttcaactt attacaatga tttatatgaa actatggcta taaaaactgt atttggagaa
     8941 aaggcatatg acttatgtgt gtcatcaaca aaatctatga ctggtcactt attaggagca
     9001 tcaggtgcta tagaggctgt tgtttgtgct atgagtatag aagatagttt tgtgcctcca
     9061 actataaaca tacaagaagt tggtgaagat ttggatttag attatgttcc aaatcaaggt
     9121 aaagaaaaaa atattagata tgcactatca aattctttag gatttggtgg gcataatgct
     9181 acaatagtac taaaaaaata tgtataaata aatattaaat ataaaactaa aaaacaagca
     9241 cttgttttaa ctgtataaat ttatattagc ttaaatttaa agtctcctaa attattttag
     9301 gagacttttt tattaagatt taagtctagg atatgttgta aatcattttg atatattgta
     9361 ttattaatta ttaagaggtt atttatatat gcaagttttc attctacaat atacaaaagg
     9421 aggactaaaa ttttgaattt tagactacca aagaaaaggt tacccaaaaa gataattttt
     9481 atatgtataa tacttattag tattattttg tttataaagt atgaccaaaa tggattgaaa
     9541 gaaagagaaa ttataaataa gggaaaatat atgtctgaaa gccttgtggc agataaggag
     9601 tatgatgaag caaaaaaagt ggttaagact tcttttgaat ctattccaga aaaaaaatac
     9661 aataaagtat ataatgaagt ttgggatatg ttaaagacta tttcatatgt tccagatgga
     9721 acgaagatag tcattgattc tttagaaaag atgagagaat cagatgtgaa attatctgat
     9781 gaatgtagat ttaatataga aaaaagatta gcatcagtgt atataatgga taataattat
     9841 tctaaggcag tagatttaac tgtaaagtct ataaagttgg ctgagaaatt ggggaataat
     9901 tatgaaaaag caagactaga tgttgatttg gcgagcatat ttttaaagat aggtggctat
     9961 gaaacaggag agaaattaat aaaggattct tttaaaatag atattgatga aggtgaaaaa
    10021 aatggaatgg ttagattata tgctattata aatctagcag aaatatatgt agaagaggga
    10081 gaatatgata aagctattga aataagtagc aggataaaag attataaaaa gtttgtaaat
    10141 acggataatt acaatgattt tgatataatg gcctctataa tgcagtcaaa tgcgtatgtg
    10201 ggcaaaaata atatacaaaa ggcaaagact tttttagaaa aagctgatta tcttataaaa
    10261 tcagatagaa cagtttatat attagataaa gatatgtact attatatggc aatgggaaac
    10321 ttagaatata aaagcgaaaa ttataattct gcaatagata attataaaaa aagtttagag
    10381 atatctacca aaagaaagtt aacccaggag aaaataaaaa atttaaataa gatattaaat
    10441 atatatgaaa aacaaggaaa tatagaatct ttaaatgagt atcaaaagat gttaataaat
    10501 gaatataaag agaacaaaag tataagagat tcagagacta gtttctatat aattgataaa
    10561 gtatcaaacg aaagtaagct atttgaaaaa actaaaaaag aaataaaata ttataaaata
    10621 ttatttaccg taattttaat tgctatatta gggtctactt ttttatacaa ccgattgaag
    10681 tattttaaag cacaaaattt acatgatggt cttacaaatg tttataatag aaaaagtttt
    10741 gatattatgt atgaaaagta cagagagaaa gatgataatt ttgcacttgt gatgatagat
    10801 attgataatt tcaagctcat aaatgataat tatggacata aatttggtga cactgttata
    10861 aagggaataa caaataccat ttgtgttatg ttagaacaag atgataaagt ctttaggtac
    10921 ggaggagaag aattttctgt attaataaga aataaatctg gtgaggaagt agcagatata
    10981 attgacagta taagggttgc aattgcaaat aaaaagtgga atgatgatgt gactgtgact
    11041 ataagtgcag gtgtagctca tatttcagat agcaaagatg tactagaaga agctgataaa
    11101 aatttatata aagcaaaaca acttggtaga aataaagtag tatataagta attatatact
    11161 atataaataa gaggtataaa tatgaaacaa tcaatagcta tagtaactga taaaataact
    11221 aaactatcat ctttcttaga agaaaatata cgtttggttt taggtaatta tattgatata
    11281 aaccactatt atctggaagt tttaaaagag aatgataaaa tacaaggtga ttttgtacta
    11341 gtaatgaatg acgatagatt aaacagtatg agaaagcatt tagtacaaga tagtaagatt
    11401 atagtgataa ggagaacact taaagaaaat gaaatatatg gattattttc aataccaaat
    11461 ggaactgaag tattggttgt aaatgataca aaagaaacta ccttagaaac gataagctta
    11521 ttttacaaaa taggagtaaa aaatttaaag tttactccat atattgaagg aaaaatttat
    11581 aaaaatatag acatagctat aacgcctgga gtaaagggaa aagtaccaag ttatataaat
    11641 aaagtaatcg accttggaaa tagatatatt gatatatcta cctttataga aataataaat
    11701 ggtcttagaa tagatgttaa agaaatacgt aaaaatttaa tggcatattc tgagagttta
    11761 ataagtttag ataatggagt taaagataat tataggcaac tgtttttaaa aatagaagaa
    11821 caagatgtta tattgaatct atcaaaagat ggaataatat ttacttcagc agatggtata
    11881 ataaacacat ttaataaaga agctttaaaa attttaggta taaatgaaaa tccacaaggc
    11941 aaaaacatag aagatatcat ttctgaagat ttaaatattt tacttgaaga caaagaaata
    12001 attgatgaag tggtatttac aaataaaaaa tatataaatg taaataaaaa aaatattttt
    12061 tctatgggga ataaagctgg gatatattat aacttacaag aaataacgta tataaaaaaa
    12121 ttagaacaaa atcttactaa taaattaaga gaacaaggtc agatagcaag atatacattt
    12181 aaagatataa aaactaaaaa taaaaatatg gtaaagtgtg tagaattggc taaaaaaata
    12241 tctaaatcag acctttctgt attaataata ggagaaagtg gtactggtaa agaattatta
    12301 tcacaatcaa ttcataatgc ttccaataga agtaatcaac cgtttatagc agttaattgt
    12361 gcagcagttc cagatagtct attagaaagt caactgtttg gatatgaaaa aggctctttt
    12421 acaggagctt taagagaagg aaaaaagggt ctatttgaac ttgctaataa tggaactata
    12481 tttctggatg aaattggaga tatgcctcca ttgctacaga caaagttact aagggtatta
    12541 caagaaaagc aggttatgcc tataggttcc cataatgtta taaacataga tgttagggtc
    12601 atagcagcaa caaacaaaaa cttactaaag atgattagag aaggaaaatt tagagaggac
    12661 ctgtattata gactaaatgt attgccaata gatgtaccat cattgaggaa tagaaaagaa
    12721 gatataataa cacttatgaa tttctttttg aaaaacaata taagactttc gccagaagtt
    12781 ataactattt tagaaaaata taattggcca ggaaatataa gagagttaca aaatgttgct
    12841 tcttatgtaa gtctaatgtg tgatagtatg gtttttagag atgacttacc accatatata
    12901 agggtagaat gtgctaacaa ttatgaagat ggatttggtt atacaagaaa agaatttgag
    12961 gaaatactga ggattctata tgaaagaaga gagtcatcct ctggaattgg aagagggttt
    13021 ataatcgaaa agcttataca ggaaggtatt gagatttctg aaagcaaagt tagaaaggtg
    13081 ctatcttatt taagtgaatg tggatacata tcatctaaat ctggtagagg aggaagtcaa
    13141 ataacctcag aggggataaa actttataat aatataaatt aagctaagta tttgatattg
    13201 aaatcacata ttttgaattt agatatttaa ataataataa acttttatat ttatagagat
    13261 taatttatat tatgtcagaa agaatattgt aatttacact taaatattaa taggttttta
    13321 aaataggatt agataggtaa taggttaagt tagaataacc cattacctat ttttatttgt
    13381 aagaaaagtg tacatagaat tagaagtaaa aaatacaact aataaaacta ttgaaaatac
    13441 tagataaata ataaataaaa ataattatag attttggcat acatattgct aattatagag
    13501 ataagacgac aaaataattg ggaggtttaa tgatgaaata caaaacaaca gggacttgtg
    13561 ctacagaaat tgaatttgaa gtaaaagaaa ataaagttac aaatgtaaac tttataggtg
    13621 gatgtgatgg aaatttaaaa gggctaaaag tattagttga aggcatgaat atagaagatg
    13681 taatacaaaa gttaaaagga atagagtgta aaacaaagcc aacatcttgc ccagaccaac
    13741 tgtctctagc attggaaaat tatatgaata taaagtaata cataaaacaa tcgattagtt
    13801 aggagtttaa ttatgaaacc aataataggg attttaggaa atttaataat aatggaaaat
    13861 ggtatgtttc caggtcttga aaggtcatat gtaaataatg attatataaa tgcagtgcta
    13921 aaaggtggcg gtagtccagt aataattcct gtaaatacag ataaagaagt tataaaaaaa
    13981 cagattgaaa tggttgatgg agtcttaata tctgggggat gggatatcaa tcctcaactg
    14041 tatggagaag aaacaagaga agaaacgaca tttatatatc cagaagtgga tgaatttgat
    14101 ttaattgcaa taagtatagc attagaactt aaaaagccta tattaggtgt atgtagggga
    14161 ctacaaattt taaatgtaag tttaggagga actttatatc aagataataa tcttatagaa
    14221 ggaagttata taaaacatac acaatcttct aaaagacatg tagctactca taaagttgat
    14281 gttaaagaag gaagtatttt agagggaatt ttaggaaaac aattacttac aaatagttat
    14341 catcatcaaa gtgtcaatca gcttggaaaa ggattaaaag ccatagcata ctcaaaagat
    14401 ggtatgatag aagctattga gaaagaggat gaaaattttg tagtaggagt acagtggcat
    14461 ccagaaatga tggtagatta ctgtgataaa atggaaaaac tatttaaata ttttataaat
    14521 atttgttcga atttataata taccttgggg ggattgaaca tgaacgaaaa gaacaaaatg
    14581 ggattaataa gtattatact tttaggtatt aatgcagtag taggagctgg agtttttcta
    14641 ttaccaggag atgcaatgaa atcatttggt gtagcaagta tatttgtata tatatttgat
    14701 atgttgttag ttttatctat ggcattctgt tttgctgagg ttgcaggtaa attcaataaa
    14761 aatggtgctg cctatgtata tacaaaagaa gcttttggag atttttgtgg ttttgaagta
    14821 ggtcttatga aatgggtaat aggatgtatt tcttggggag ctttaatagt aggttttcct
    14881 acatcattat cagcagtatg ggctccagca ggtgaaccac atatacaaaa aattataatt
    14941 gtagccatga tagttgggct tacaattata aacttattag gtgtatctct atcaaaaatt
    15001 gtacaaaatg ttataactgt aggtaaacta attccattaa tactatttat aggaataggt
    15061 atatttttta taaaaggagt taattttact tcttcaacaa tggtacctcc aggagctgga
    15121 gcaacagagt ttggagcagc agcactttta atgttttatt catttacagg atttgaatct
    15181 atagcagttg cagcagaaga tatggagaat ccacaaaaaa atataccaat agcaattata
    15241 agtgtaatag taattgcatc aataatatat atattaaatc aagttgtatg tgttggtata
    15301 ctaggagatt cattatctag tacatctaca ccagtggcag atgctgcaag aatatgcttt
    15361 ggaaatatgg gagctggatt ggttaccttt ggaacattgg tttctgttgg tggaatttgt
    15421 atgtgtggtg cttttgtaaa tccaagaagt tgtgtagctt tagctgatga taaaatgtta
    15481 ccgagaatat ttgcaagaaa agataaaaaa ggtacaccat atgtagcgat aatagctact
    15541 atgttaatca ctataccaat agctctatct ggaagttttg ctgaattagc agcaataagt
    15601 gcagttgcta gattcataca atacatacca acatctttat ccgtattagt gtttagaaag
    15661 aaaagaccag aattagtagg tacttttaaa actccttttg gagcagtgat tcctctaatt
    15721 gctgtatgtg ttggaacatg gttattattc caagcatcta tgcatcaatt aattatggga
    15781 ttaggagctt tggcaattgg agtaccatta tactttataa tgaagtctta taatagaaaa
    15841 gtctatggtg aaaatttaaa gaaaatagtt taattatgtt ataacagttt attgagttaa
    15901 agttagacat tggcagaaaa ttaaatacaa ataagtatct ataaggctat attaaaatat
    15961 tattaatttt ttattttaat atagccttaa attgttatca ataagtgaaa aatattgtaa
    16021 caatagaaga acaatagtat tatgtttata gacaaaaaac ttattaggag gtaaatttat
    16081 gccaacaata acattaaaaa atggtgtaga cgtacttatt agagaaggag taagggaaga
    16141 tgctcaaagc attatagatt tttataatga agtgggtgga gaaactcatt ttctgtcatt
    16201 tggaaaggat gaatataaaa tatctttgga ggaacaagaa aatgctatag aatcagcaaa
    16261 agcatctgat aattctgtta aactgattgc atttatagat ggtgaaatag ttgggattgc
    16321 aacgattgat tctaatcaaa aagcaaaagg aaagcatgtt ggagtattag gaattgttgt
    16381 aaaagaaaaa tattggggaa ttggattggg taaaaggctt atgttagacc ttatagaatg
    16441 gtgtaaatca aatggaataa ccaagaagat aactcttgtc actaatgaag aaaattataa
    16501 tgctatagga ttatacaaaa aagttggatt tgaagtagaa agcatactaa agaaagaatg
    16561 ttattataat ggtgtttata ctgatttaat aggaatgtca cttttattgg gaatataatt
    16621 agtgtacatt ttatctcgaa aaaagtatat taagtatggt ataattaaaa aagaatataa
    16681 cttaatataa ttttggagga cgaattatga aaaatctgtg taaaatatca gatgattatt
    16741 taaacagcaa gcttaagtat ttaaagttat tatcaaaaca atatccaagt atatcaaaag
    16801 caagtacaga aataataaat ttagaggcta tattaaatct tccaaaggga acagagcatt
    16861 ttataacaga tgtacatggt gaatatgaac catttgtaca tgtattaaaa aatggttctg
    16921 gtgtaataaa gagaaaaata gaagaattgt tttcaaatac aataagagac agcgaaaaaa
    16981 aaatgttagc aactcttgta tattatcctg aacaaaagtt agacctaata attaagcaag
    17041 aggaaaatat agatgatttt tatagaataa atatttatag acttatagaa ctttgtaaat
    17101 atgcttctag caaatatact aggtctaaag ttagaaaact gttaccagaa aattttaaat
    17161 acataataga agaacttttg catgagcatg ttaaaagtga acataaagaa gagtactata
    17221 aaagtatagt tgaaacaata gttgacatag gaatagctaa ggagtttata attgctattt
    17281 ctacagttat acaaaaattg gttgtagata gacttcatgt aataggagat atttatgata
    17341 gaggtccaag accagatata attgtcgata agcttattga acatcattgt gtagatattc
    17401 aatggggaaa tcatgatata ttgtggatgg gtgcagcctc aggtgaaaaa acttgtatag
    17461 caaatgcact gaggatatca gctagatatg cgaatttaga cattgtagaa gacatatatg
    17521 gaataaatct gttgcctttg gccacttttg ctatagaaat gtataaagat gacccttgta
    17581 aagaatttat tccaaaggtt aatgaccaaa gtgtaacaac aacagaaaag tctttaatgg
    17641 caaaaatgca caaagcaata agtataattc aatttaagct tgaaggtgag gttataagac
    17701 gaagacctga atttgaaatg gaacatagac tcttgcttaa tatgataaac tatgatgaag
    17761 gtacgattaa tttaaaaggt aaaacatata aattaaaaga tacttattta cctacaatag
    17821 acaaaaaaga cccatataaa ttaactatgg aagaaagaaa tgttattgat aaattagtat
    17881 cttcatttag aggtagtgaa aaattacaaa aacatgtttc atttttgttt tctaaaggaa
    17941 gtatatattt aaaggctaac tcaaatttac tgattcatgg atgtgtaccg ttaaatgaag
    18001 atggaagctt tatgtctatg aatataatgg gaaaagagta taaaggtaag gctcttatgg
    18061 ataagatgga gtctctagca agagaaggat ttttctttaa agataaggca gaagaaaaac
    18121 tgtatggcat ggatattatg tggtatttat ggactgggaa atgttcatca ttatttggta
    18181 aagatgatat gactacattt gaaagatact ttatagctga aaaagagact cataaagaaa
    18241 ataagaaccc atattttaaa cttagagaaa atgagatggc ttgtaaaaga ttatttgaag
    18301 aatttgattt agaacttgat gaatctcata taataaatgg tcatgttcct gtggagagta
    18361 aaaatggaga gagcccaata aaagctaatg gtaaaattct cgttatagat ggtggttttt
    18421 ctagggctta ccaaaaaact actggtatag ctggatacac tttgatatac aattctagaa
    18481 ctttgcaatt agtatcgcat gaaccattta attctgctga agaagccatt gcaaatgaaa
    18541 gtgatatctt atcgacaact gttgtagtag agcataaggc aaagagaaaa atggtgagag
    18601 atactgatga aggagtaaag atacaagagg aaatagaaga tttaaaacta cttttaatgg
    18661 cgtataagaa agggctaata aaagaaatgt agatgttata gaggcacttc atgattgaag
    18721 tgtctttttg ttaatactta ttaaatatat tataaagatt aataatagta gtttatatta
    18781 tacttactaa gtgaatccaa gataaatggg ttcacttttt ttatttataa acattattaa
    18841 aaaaatatag atgttttggt tatattcctt gtcctttata aatagaatta tataaacaaa
    18901 ggaggaggac aagagatgaa taaactttct gatgaaataa taaactctct ttctacaact
    18961 ataagagaaa aggtagaaaa agtctcaaac aataatctga acatagaaga aattaggtta
    19021 cgctcacaaa aaccattgat actaaatgca aactctaaag attattttta caatcaaaaa
    19081 actatgacac ttgatttaaa tcaacaaaac tcatatgtag taacaagaga agatgtagag
    19141 caaacttttc aaataatatg taaatattca atacattcat ttatggatga cataaaaaaa
    19201 ggattcataa ctttgagagg aggtcataga gtagggttag ttggaaaagc aatagtagaa
    19261 gatggacaag tcaaaaatat aaagcatata tcatctttaa atataagggt atcaagggaa
    19321 attattggat gctcggataa gattttaagt catatcataa agggaaaaaa tcagattaat
    19381 aatactttga taatatcacc acctcaatgt ggaaaaacaa ctttaataag agatatagta
    19441 agaaatttaa gtaatggtaa tgaagattat ggatttaaag gtttaaaagt ggctttagta
    19501 gatgagcgta atgagatagc aggatcttat ctaggtgttc cacaaatgga tgtgggaata
    19561 aggactgata taatagaaac ttgcccaaaa gacttgggta ttacaatgct tttaaggtct
    19621 atgtcaccaa atgttattgt gacagatgaa attggaagtg aaaaagaaat aaaggcatta
    19681 tacacagcat taaatggagg tataggatta ataactactg tgcatggaga ttcaatagag
    19741 gatatacaaa atagaaaaga attaaataga cttctggata aagagttatt taaaaaggtt
    19801 ataattcttt ctgcaaaaag aggagcagga acaattgaaa aaatttatga tttagaagaa
    19861 aagagatggt attttgcaaa ttaaaataat tattatagct ttcttgatag gaagtagtta
    19921 tttgataggt gaacaaatat acaaaactta tactcgtaga cataaacaat taaacgattt
    19981 aataagagtt ttagaaattt tgaggatgga tttatctttt ggactttata cattagaaga
    20041 aatctttaat aggataggtg gaaataaaga gttttgtttt tggaaatttt tctatcaaat
    20101 atcagaagga cttcacaatg aacaaagtaa aactttggaa ataataatat cagaaaatat
    20161 tgatgtatta agtaaagaaa cttatctagg caataaagaa attgaggaac tgaaaaatct
    20221 aatacttact ttagggaaaa gcgatataga gtcacaacaa agaatgatag atttatctat
    20281 agaaaatttg aaaaaacaaa cctatgagac aaaggaagat ataaacaaaa aaggcgtatt
    20341 gtataaaaaa ttagtgacat tcataggtat aggtatatgt attatattga tttaatatgg
    20401 ggaggtttat tatggaaata tcattgatat taaaggttgc aggtgtcggt attctaatat
    20461 cagtattgaa tatgatattg gaaaaaacag atagaaaaga ttgggcaggt cttactacat
    20521 tagcaggtgt aataatcgta ttgggtatgg taataacaga aataagtgac ttgtttaata
    20581 ctgtaagaac aatgtttcaa ctttactaaa gaggagggag taatttggaa ataatgcaat
    20641 taataggaat tgcaatcatt tcaactacac tctgtttagt aattaaaaaa gatagaccag
    20701 agatagcaaa tttcatagct ataataactg gagtaataat actattgtca gttatgttta
    20761 agctaaattt tatagtagat agtatacaag atttggctaa caaggctaac atcccgacta
    20821 tgtatatatc attaataata aaattaattg ggatagcata cttaatggaa tttgcgatac
    20881 aactttgtaa agattgtggg gaaggaaaca ttgcttcaaa actagaattt ggaggtaaaa
    20941 taatagttat gtcaatgtct ttccctatac ttttgtccat tgtagaaatg gtggtgaata
    21001 taattccata gatgtgtatc ttggaatgaa tataagtata ttagagagct ttcgttgtat
    21061 tgaggtttat agagtgaaga gaggcatggt tgcttatgaa aaaaagattt ttaccaatga
    21121 ttataggttt tttatttact ttcttttttg taaatatctt tgctattatg atatttgcta
    21181 atgaagtacc aagtagtgaa gataaagaat atggtgaaac aaaaaatagc atagataagt
    21241 atatagatgg tcaattagac aagctagata taaatgagat tcaagactat ataaataaag
    21301 aaatagttat taatgatgtt aatttaaaat catttgtaaa agatttaatt agtggagaaa
    21361 aaaatatctt agatttattc aataaagatg gattgaagat attgatgttt gatgaattta
    21421 aagcaagttt aaaggtagta gcagtaattt tggtactggc tctgctatca tctattttaa
    21481 agagtctgga aaactctttt tcatcaggtg cagtaagtca aatagcaaca tatataatat
    21541 ttatcacaat ggtatcactt acacttattg gttttaaaga tgtattacag atttgctatg
    21601 atgcaataga ccatactgta ggtcttatgc aagttataat gccaatatta ataacatttt
    21661 tacttttaat tggattccca ataacgtcga ctactttgaa tcctatcttc ataggaggag
    21721 taacatttat aaatgtattt tttaaaaatt ttctatttgt atctattact gttgcatttg
    21781 gaattttaat aataaacaat ttatcaaaaa atataaggct aaagagattt ttctcctttg
    21841 taaaacaaat aaattatgtt tctattggag ctatgtttac tgtttactta ggtcttgtat
    21901 ccatacaagg actgtatgta accagttttg ataaattcag tgtgaagact gctaaatttg
    21961 ctataggtaa ttttattcct gttgtaggtg gatttgtatc tgactctgtg gatattttat
    22021 tatcttcatc tcagcttata aaaaatatat ttggaggaat agggcttatc ttacttgttg
    22081 gaatttgctt acttccagta ataaaaattt tatcagtaat agtagtgtac aaattagcag
    22141 caataattgt agaacctgtt ggagaggatg gaatatctaa ttttttaaat gaagtggcaa
    22201 atttaatgat aataatgcta gcatcagtaa ttgctataac agtaatgttc tttgtaactg
    22261 tagctatctt gacctcgata agtgtcgtaa gtcaagggta atttatatat cagtgaaaaa
    22321 taattacatt taatctaata tttttagaga ggaggatgct atgttagagg gcataaaggc
    22381 atggatagtt agtgttttga taggagcatt tatagtaaat atagtagata tgattttacc
    22441 aagttctaag ataaaacctt atgtcaacct agttttaaac tttatgtttg tatttattgt
    22501 aataactcca gtagtaggat ttttttcaaa agatatgagt ttagaagata gaatattaaa
    22561 atctatggga aactacaaca agcagtatgt agatagtaca aatgctttgg caaaagagac
    22621 tggaaataat agtctatcca agggatatga ggatgggtta aaagaagtac ttaaattaaa
    22681 acttgatgaa tatggttatg atttagaaga tatagagctt aatggggcaa atataaataa
    22741 tataaaaata aaagaaaaga ataatagtgc aaaaagtaat aacagttcca atgaagaaaa
    22801 taaaaataat agtactaaaa gagaggaaga aaacataaac tctaatgaca aagaaaattc
    22861 taaacaagtc ttcaaaaaag gtacagagta tgggttgaac ctaaatgaag aaaaattaaa
    22921 aaacgactta ataaaggtgc tggatgtttc tatagaagat atacaaattg ataaatagga
    22981 gttgggagaa tgttgaaaaa cttaaatgac aaagataaga gaaaggtata ttcactaata
    23041 actatagcag gaatatgtgt ggtttcatta gtattattat cttgttttcc tagtagcaaa
    23101 agcgataaac aagttggaaa aacagagact aataaaaatg ctgaaaagca agtcactaaa
    23161 gaacaagaaa aagatgattt agagtcaaaa ttaacagcaa tactatctaa aattgatggt
    23221 gcaggagacg ttgatgtaat ggttacattt gaatcaagtg aagaaataca acctgctttt
    23281 aattcaaata atacaacaga aacaacagag gaaaaagatg cacaaggtgg agaaagaaca
    23341 gttacgactt ctagtgaaaa taaaacaatg ataacttcaa attcaagtga ccctgtagtt
    23401 ataaaaacta cagagccaaa gataaaggga gtgatagtgg tagcaagtgg agcaagtgac
    23461 ccaagtgtta aagagacact ttatagtgca gtacaaacat cattacaagt agctggtcat
    23521 caagtagaaa tatattctaa ataaatacat ataaccgggg ggataaatga atgaagttta
    23581 attataaggg aagaggattt gtaataataa ctttaactgc aatgttagtg gtagtaggaa
    23641 cagtgaatta tcaattaagt aagaaatctt tattagaaac atcaaaagag tttaaggcat
    23701 atgaagaagc acagttacaa aaaaatactg atgagagtga tagtagtaag acagaggatt
    23761 ctagtaatat agataaacaa gatggtaagg aaagtgctga tattgatata gttgatagca
    23821 aagctagtaa agtaaaagaa aaggcaactg agacaagtaa ggaaataaaa gctcaattat
    23881 catcagagaa aaatatgaaa aaggcatctt atattttaga tatgaaaatg aatagagaaa
    23941 aacaaagaaa tgagttagtt caagatttaa atgaaatgat aaataatcca tctacaacag
    24001 aagaatctag aaaagaagct tctaatatga aattaaatat agttaaaatt caagaaaaag
    24061 aacttcaaat agaaaacctt ttgagtacaa aagggtatga agaagcgtta gtttatataa
    24121 gcgataacaa agttaatgta gttgtaaatg aagctaaatt agaaaagaaa gatgcagcaa
    24181 aaatatttga tttagttgca gaacaagcca atgtgaagta tgaaaatatt aaacttacaa
    24241 ataataatag taataagtaa agtataaacc tcagaattaa ctgaggttat tttcttgcaa
    24301 agtagacttg tatttggtat tattatactt ataaaaatag ttccttaaaa tcaggaggta
    24361 agttttaata tggaagataa taaatttgga caagtaaaaa tatctaatga tgtaatagct
    24421 acaatagctg gtttagcagc attagaagtt gaaggcatag aaactacagc aacattaaca
    24481 gataagttgt taaaaaataa tggagtaaaa atacaaatcg aagaagagga tgttaattta
    24541 gatgtaatgg ttacgataaa gtatggaatg tcaataccag atacagcttt taaagttcaa
    24601 gaaaatgtaa aaaatactgt tgagacaatg acaggactga aggtttctca agtaaatata
    24661 cacattcaag gaatcagctt taagaaggat aaagttgata aagaagaagc aaaagcaact
    24721 aagaaaaatt aatattagcc ctctgaaaag tcagagggtt ttttgctggt aattgatttt
    24781 atatggataa ttaaacttaa aggagaattt tgattgatga aaaaagatag ggcacaaaag
    24841 agtacaacaa gagaatatat aatgaaactt atataccaaa taaatattaa taaagaagat
    24901 tttgaaactt tagaagataa agtagataat tttttaaaag ataattcaga acatattata
    24961 aatagatata aagaacttgc acttcaatac tcaaaaaata caaatttaaa gttagaagat
    25021 actgaaattg aagatgttat agacaaaaaa tatataaata cagtatgcaa agcattgaaa
    25081 gaaaatcatg acaaaataga tgagttaata aataagcatg ctaaaaactg gacagtagat
    25141 agaatgccaa aggtagatgt ttctatactt agattgtctg tgtgtgaaat actttatcta
    25201 gacactccta ataaagtatc aataaatgaa gcagtagaac ttgcaaaaat atattgtgat
    25261 gataagtctc ctaaatttat aaatggtata ttgggaagtg ttgttgatga aattgggaaa
    25321 taatataata attggaattg atactagctg ctatactact tctatagcag ctatctcttt
    25381 agataagaaa gttatattaa atgaaaaaat aatgttagaa gtaagggata attcaaaagg
    25441 tttaaggcaa agtgaagctg tatttcaaca tatcaataat ttagggattc ttagtgatag
    25501 gataaaatct tttaaagata agtttaatgt agaaggagtt tgctcatcaa aaaaaccgag
    25561 acctgttgaa aactcatata tgcctgtatt caatgtaggt cataattttg gaaaattatt
    25621 gtctagtata tatggttgta ggttttatga gactactcat caagagaatc atattgaagc
    25681 aagtttatta aatagtaaat taaaaaataa taataaattt atttctgttc atatgtctgg
    25741 tggtactaca gagatacttt taacaagcaa acaagatagt catcacaatg tatgtgatac
    25801 taatttaggt aaaattgcca aaataagtat taaaaaagat gataaaagta agttatacaa
    25861 taattttgga tataatatag atataattgg aggaagtaaa gatattagct ttggtcaact
    25921 tatagataga gtaggaatta agcttggata taaatttcct tcaggaaagt atttggatga
    25981 aaatgcttta aattgtaatc ttaaaataga aagtggtctg aaaacttctg taagagatgg
    26041 gtatatgaat ttatcaggat tagaaaatca ggtaaataag attataaatg ataatggaga
    26101 taatactaat caaaaagaat atatatctaa attggtatta gattcagtag ttagaaatat
    26161 gtttaaatct ttagtgtatt tatgtgaaac ttataatgta aatgaagtag tatttgctgg
    26221 tggagtttct gcaagtaagt atattcttag agaattaagc atgaagttaa gaaaaaagca
    26281 tatagaagct tattttacag aaccacaata ttcaactgat aatgctgtcg ggtgtgctat
    26341 aataggattg aataactttt taggagaaag agtatgaaac taagagcttt agatataagt
    26401 gaagcaaact catatattaa aagaatttta ataaacgacc caatactttc taatcttaaa
    26461 gttaaaggag aaatttctaa ttttaaggtt catagtagtg ggaatgtata tttatcactt
    26521 aaagatgaaa catcaaagtt aaactgtgta atttttaaaa gtaattttaa tcgcaattta
    26581 aaattagata atggtgtaaa aattatagct aatggatata tatcagtcta tgaaagagat
    26641 ggtgcgtatc aattatacat taatgaaatt gaaatagagg gaataggaaa tttacacata
    26701 gagtttaata gattaaagga aaaacttaat aaagaaggat tatttgaccc taaatacaag
    26761 atacctatac ctaaaatgcc aaactcaatt ggcgttataa catctccaac aggtgctgtt
    26821 ataagagata taataaatgt aataaaaaga agatatccga aagttaatat aaagctttat
    26881 ccagtaacgg ttcaaggaga taaatcagct gaagaaatct gtgaagcaat tagatttttc
    26941 aatcatatga agaatgttga tacacttata gttggtagag gtgggggttc aatagaagaa
    27001 ctttggtctt ttaatgatga aatggtagca agagaggttt ttaattctca aattccgata
    27061 atatcagcag ttgggcatga aacggatttt actatttgtg actttgtgtc tgatatgaga
    27121 gccccaacgc catcagcagc agctgagatt gctactccat cattggatga tataaactat
    27181 aaacttggaa acataaaaag taggatgagt aagtctctta caaatcaaat agagctagac
    27241 caatataggt tagaaacagt atttaataag ataaataact atttagattc gtacacaata
    27301 aaagataaag ttatacaatt agacaaaata tatgataaaa taatttttgg aatagaaaat
    27361 aatttaaaat tagaagatga aaaattagta aaaattggag cattactcca taatttaagt
    27421 ccattagcta ctatggatag aggttatagt ataactcaaa aaaatggaaa agtaataaat
    27481 agtataaaag gattaaaagt aaaggatagt atagatatag tattaaaaga tggaaattta
    27541 gaatgtatga tagataaaat tgaaaataaa gagggatagt atgaatttaa cctacgaaga
    27601 agcttataaa agattagaaa gtattttaag tgaattagaa tctaaaaatg ctagcttgga
    27661 tgaatcttta agcctatatg aagaaggtat aagcctttat aaacattgta ataagctttt
    27721 agatgatgct aaattgaaaa taagtaaatt taatcaattg ggaatagaag aagactttaa
    27781 aatagaggag gaataaaatt ggaatttaaa caatgtctaa aagaaaaagc aagttttgta
    27841 gaaaaagtac ttaaagaata tatgcctaaa gaagaagggt atcaaaaaac tgttattgaa
    27901 gctatgaact atagcttaag tgctggaggt aaaagattaa gaccaatact tacattggag
    27961 gcttgtaaaa tagttggagg taatgaagat gaagctattc cttttgctat tgcaattgaa
    28021 atgatacata catattcact aatacatgat gatttgccag ctcttgacaa tgatgattta
    28081 agaagaggaa gaccaacaaa tcataaagta tatggagaag ctatggggat tttagcagga
    28141 gatgctttgt taaactatgc ttttgaagta atgcttgcag gctcaatcaa taaagaaaat
    28201 ccagaaaagt atctaaaagc tataaatgaa attgccaaag gtgctggtat atatggaatg
    28261 ataggtggtc aagtagtaga tgtagaaagc gaaaataaac aaattgaaaa agaaaaatta
    28321 gattatatac atatgaataa aactgctgca atgatggtag gctgtatgag agcaggagct
    28381 actataggtg gagcaaattc tgaacaaatg gaagaaataa ctaaatatgc aaaaaatatc
    28441 ggattatcat tccagatagt agatgatata ctagacatag taggagatga agctaagtta
    28501 ggtaaaaagg ttggaagtga tatagaaaat cataaatcaa catacccatc tcttttaggt
    28561 ttagataaat ctaaagaaat tgcacataat ttgattgatg aagcaaagaa aagtatagaa
    28621 aaattatctg atgatgtaga ttttttaaag ggattggctg aatatataat agatagagaa
    28681 tactaaaata tacagctaaa atcgaggagg gaaaaatgga ttttttttcg gagattttta
    28741 acaatggggc tttgggaata agtctgattg cttgtttctt agcacaattt ataaaaatat
    28801 ttactggtaa ggaaaaaaga attgagttat caagaatact tatttcagga ggtatgccta
    28861 gttcccatag ttcttttgtt acaagtttag ctacagtggt aggtattgaa aaagggttta
    28921 attctactga ttttgctata attaccgtgc ttgccttaat tataatgtat gatgcagcag
    28981 gtgttagacg ggctgttggt aaacaagcta ctatattaaa tcaaatggtg gcagatatac
    29041 agcatggaaa gcatatagag cagaagaaat taaaagaatt aataggtcat acaccactag
    29101 aagtttggtt tggagcttta cttggaatag taacagcttt aatattgatg taaattgaaa
    29161 atttacagaa taaaggtgag gataatatgt ataaatattt agataaagta aattctccaa
    29221 aggatataaa aaatatgagt atagaagaaa tggatttact tgcaaaggat ataagaaagt
    29281 tcttagtaaa atctgtttca aagacaggag gacacttagc ttctaatcta ggagtggttg
    29341 agttaacatt agcacttcat aaagtatttg atagccctaa agataagatt gtatgggatg
    29401 tagggcatca atcttatgtt cataaaatag ttactggaag aaaagattgt tttgtatctt
    29461 tgagacagtt taatggacta agtggttttc caaaggagaa tgaaagtcct catgatattt
    29521 ttgatacagg acatagcagt acatctattt ctatagctac aggtattgcc tgtgctaggg
    29581 atataaaaaa agaaaactat agtgttatat ctgtgatagg agatggttct ataacaggag
    29641 gtatggcact tgaagcttta aatcaattag gatatataga taccaatatg atagtaatcc
    29701 ttaatgataa tgagatgtcc atagataaaa atgttggagg aatgtctaaa tatctgtcaa
    29761 gtattataag aaactcaaca gttgagaaaa tgacagatga agttgataaa attttaaatg
    29821 ttacacaaac aggtgaaatt ttatctaaga ctgcacatag atttaaagat aaactaatgt
    29881 atagcttttc tcctcaggac tgttcatttt ttgattcatt aggtataaga tattatggac
    29941 ctatagatgg ccataatact aaagaactaa tagatatatt gagaaaagct aaacacaaaa
    30001 aagggcctgt tcttttacat gtaattacga aaaaaggaaa agggtacaga tttgcagaag
    30061 aacaacctga taaatatcat ggagtatcaa agtttgatat aaagacaggt gttacatctg
    30121 caaaagttaa gtctatgtca attagtgttg gagaaaaact tgttgatatg gctaatagta
    30181 atgaaaatat agtagcaata acagctgcaa tgccatctgg tacagggcta aacctgtttg
    30241 aaagtgcata tccaaaaaga tattatgatg ttggtatagc tgaacaacat gcaacaggat
    30301 ttgcagcagg tcttgcaaaa aatggtatga aaccttactt tgctgtgtac tcatcatttt
    30361 tgcaaagggc atatgaccaa gttattcatg atgtatgcat aacaaaaaag ccagttactt
    30421 ttcttataga tagagctgga ttagttggaa atgatggaga aactcatcat ggtatgtttg
    30481 atttaagtta cttaaattct attccaaata ttgtagtaat ggctccaaaa gacacaagag
    30541 agatggagct tatgatggat ttgtcattaa aattagattg tccactagca attagatacc
    30601 caagaggaag tagttattac ctagataagg gagagtatgg agagattgta ctgggtaaat
    30661 atgaggtatt agatgacggt caagatacag tcatactttg tattggaagt atggtaaaac
    30721 atgctttaga ggctaaagaa atattatcaa gagaaggaat aaatccgaca atagttaatg
    30781 ctagattctt aaagccaatt gatgaaggta tgttaaaagc attattaaaa aatcataaaa
    30841 atgtagttac tatagaggat aatattgtaa ctggaggatt tggaagtaga ataaataagt
    30901 ttattataga taatgaatat aacgtaaata tacttaatat agcaatacca gaagaatttg
    30961 taaaacatgg caatatagat gaattatatg attttgtagg attatcgcca aaaagtattg
    31021 ctgataagat aaggaaatta gttattgagt aaaagtctaa tgtagatatt gtaaattaaa
    31081 atttatataa aatatagaat ttatcaatta gaataaatat caagtgtgtt acttcaagct
    31141 actttagtta tcattaaagt agcttttaac agaaaggtaa ttgtatgaaa aaaagaatag
    31201 atttattatt agtagaacaa gggtactttg aaagtagaga aagagccaaa aaagcaataa
    31261 tggctggatt ggtttttgtt gataatcaaa ggtgtgataa ggctggtaca gaagtaaaag
    31321 aagattgtag tatagaagta aaaggaaatc caataccata tgtcagtaga ggtggtttaa
    31381 aacttgaaaa agcaatgaaa aactttgatt tgactattga tggaaaggta tgtatggata
    31441 taggggcatc cacaggtggt tttacagatt gtatgctcaa aaatggagca ataaaagtat
    31501 tttctataga tgttggttat ggtcaacttg catggaaatt gagacaagat gatagggttg
    31561 tgtgtatgga aagaaccaat ataagaaatg tgacaataga agatacaaag cagtttgctg
    31621 attttgcgtc aattgatgtg tcttttatat cgttaaagtt agtacttcca aaggcaaagg
    31681 agttagtacg tcatgatggg gaagttgtcg ctttaattaa acctcaattt gaagcaggaa
    31741 gagaaaaagt aggtaaaaaa ggagtagtta gagaaaaatc tacacatata gaagttataa
    31801 aaatgatttc tgatttctca gtcgaaaatg gatttgagat tttagggtta gatttttctc
    31861 ctattaaagg tcctgaaggt aatatagaat atctaattca tttgagaaat ggaaatgaag
    31921 gatatgaatt tgatggtgag acatacaata acaaaatagt agaagttgtt gaagcttctc
    31981 ataatttaga caaataggtt aaaagggggc ttagatttga tcctcgaatt atatatgaaa
    32041 aattgtgcct tagttgaaga actaaggttg aatattgata aaaacttaaa tatacttaca
    32101 ggtgaaactg gttcaggaaa atctataata atagatgcac ttggactttg tttaggtgat
    32161 aaatatgata ggtctttttt aagaaaagga acagataagg gacttgttga ggctgtattt
    32221 ttttcagaca atagatatct taaaaaaata ttagaagaaa atgatataag tatggaagat
    32281 gataatttat tggtaataac taggttgata tactcagatg gtaagagtac tgctagagta
    32341 aatggaagga ctgttaaagt gtctcttctt aaagaaattg catctacact tatagatata
    32401 catggtcaac atcaaaatca agctttgttt aataaagata ctcatttaaa atttctagac
    32461 ctttttggag aaaatgaatt ggaagagttt aaaattgctt ataaaaaggt gtaccataag
    32521 tatagtgaag taaaaaaagc tttaaattgc ttgacagaaa ataaagatga gatgcaaatt
    32581 caacgagaaa tagatttatt aagatttcaa ataaatgaaa ttgaagctgc aaatctaaat
    32641 aagaatgaat atgaagattt attaaaacaa agagaagttt atagaaatag tgaaaagata
    32701 tataataatc taaattcgag ttatagcaag ttacataatg gtgagtataa tgttattgac
    32761 ctaataggtc ttgcatctaa ggaacttaat gacatatcta aatatgacag tgttttaagt
    32821 gaatatagtg atactgtaga aagaatcatg tatgagttac aagacatatc tggtgagata
    32881 agaaattaca aagataatat agactttgaa ccttatgagc tagagcagat tgagcttaga
    32941 atcgacgaga ttaataactt aagaagaaaa tatggagaca gtatagatga tatatttgag
    33001 tattatggaa aaattaaaga tagattagat gaaatattaa acagagatga aagagttgaa
    33061 cagttaagaa gcaaactgat gaatatagaa gaagatttaa aaataaaagc cagtaaattg
    33121 actaaagcaa gaatagaagt agcaactact ttagaaaaaa tacttcttga tgaattaaaa
    33181 agcttaaata tgaaaaatgt aatgttcaag gttaattttg aaaaaggtcc atttacttta
    33241 gatggagtag atgatattga atttatgata tcttttaact taggagaaga tattaagcct
    33301 atatataaag ttgcatcagg tggtgagatg tccagattta tgttagcgtt taaaaccata
    33361 ttggctgata tagatgatat tgatacatta gtgtttgacg agatagatac tggaataagt
    33421 gggatagcag cacagatagt tggtgagaaa ttgagtgata tagcaaagaa aaaacagata
    33481 atatgtataa ctcatttacc tcaaattgct gcaaatgcag acactcatta ttgtatagag
    33541 aaagatactt caaataatag gacgtttacc aatgttagta agttaaatga atctcaacga
    33601 aaaaatgaaa ttgccagact tatagcaggt aataatataa cagaaaaaac tattgaacat
    33661 gcaagtgaaa tcattgaatt ggctaaaaaa tgttagtgaa aaacaagcat tttaataggt
    33721 gtaaagaatt tttatagaaa tgctttacac ctatttttta taatgaaatt attttaaaat
    33781 atctagtgcc tatattgaag aaaagtaggt ttgaaaatgg aataaaattt gtataacttt
    33841 gtaactttga aatttctaaa tgcttaagta taatattatt tattaaggta gtagtgaggg
    33901 gaggcataaa atgaataaaa aagatactat gcacttaatt tttataattg taatttttat
    33961 tttattatgg tatattgtgg tagcagtaag tgagattaat aaaaatattg aaagttgtag
    34021 taacaaatta gattatttgt cacaagagct tatgagtact aagtcggata ttagtaatac
    34081 tataaatgaa gaaatgtcaa aaagttatat aacaaaaagt attgacttaa aagtaaaaaa
    34141 aatcgagaaa aaagaatgta ttattgatgt agatgttcaa ttaagtaaac ttggaaaaaa
    34201 tggaaaagta ttttttatgt ataaagaaga tagtgataaa tggaatgaaa ctgagatgac
    34261 aaaatatgga gaattatcat atgcatgtga aataaagata aatacaggaa gtgaatatga
    34321 ctataaagta gttacaagtg gagctatatc tgaaagttct gatgtgcaaa aatttactaa
    34381 atctgattat atgcctgaac aacccatatt taattctggg ataagagata atagagaata
    34441 ctttattgaa atagtagaaa atagtaatct tttcaatcat gagagtgaaa agtcaaaaaa
    34501 taaagcttac gataatatta gattagaaaa agtagatatt attgtaaatg aaggaaaaaa
    34561 agacactata tacaaagcca aattagctga aggcttagat gatggcaaaa ctaataattc
    34621 aaatagaaat caagtgaatt atgaagtaag ttttcctaaa agggatattg atgacataat
    34681 ttatattaaa gctaaactta catacaataa tggagtagaa tatacaaagg atataactga
    34741 agatataact atgggattac aagatttaga aaaataaata catatttaaa taaatattca
    34801 aatagatttg ttcaataaaa tagagtataa ataaaactgt agtagtttta cttatactct
    34861 attaaaaaat tataatttta attccatata tctagcccct tcaattggat tataagtata
    34921 aggttctata tcataaaaac caaacttttc atataatcct tgtgcacttt tcatgcttgg
    34981 aagagtatct aatctcatgt gtgtatatcc aaatttttta gcttcttcaa tgatttcttc
    35041 caatagtatt tttcctattt ttaatcctct aaattgattt cttacatata atctttttaa
    35101 ttcacatatt ttaccttcaa gtttttttaa agcaacacaa cctgccaaat tttcatcaac
    35161 aaatgccaat atcaatgagc ctgaaggttt tttatatttt cctggaagtg tttttaattc
    35221 attattaaag tcttgaaaac ataagtctat atttagagaa tttgaatatt cagtaaatag
    35281 aagttttaca ttttcaaggt tttctaaatc tttttcttca acaaattgta aagttatatt
    35341 ttgagccatt ttatccgcca ttatatacac atgtttatat aatgacttca cctccttgat
    35401 atatgtatat ttttcttaat atcaattaga ttttaatacc attacttttt caccaccata
    35461 gtcaagctct ccattaaact caaatccaaa atctttataa agcttaatag ccattttatt
    35521 gtcttcgaat atactaagat atagttcatc acagttatat tcatttttaa gatgatttac
    35581 aagaaaatct aatgatgctt ttccatatcc tttaccttga tattttgaat caatcataaa
    35641 tctatcaagc caaactctat catcttctaa acgaccatac atagcaaatc ctattaaaga
    35701 attttcatca tatattccaa caggtaccca agctgttata aatttagatt cagcaataga
    35761 aagtgcattg ctttctatat aatctaactg acttttatct acagacaaac taactaaatc
    35821 atgccaatta tttatgtctg caattcttac atttaatttc aagatattac cgcccttcaa
    35881 actttttgtt acaatctaat actatcatat tatgtattaa aaatcactta ttaagatttt
    35941 aaataaactt tttaaatgaa taaattctca ggaaaaagga attataaata cataataata
    36001 cagcatagga gtagatggat atatgaacaa aataaataaa aatttcaaaa atatttggat
    36061 aatattagga gctgtatcga tttttaccat ggttataatt tttaataaaa attgtaatgt
    36121 taataaagag actcaaatag aagcttttgc aattaagaat catgataaaa aatttgtata
    36181 tcctatggga aatataattg gagtaaaagc aaatacagat ggtgtattgg tcttaggata
    36241 tgaggaagag gatgtagact atattggagg catacaaatc ggtgataata tagtaaaaat
    36301 agataataaa aggataaaaa atagtcaaga tgtatcagag attttgaata agattaaaaa
    36361 aagtaaagtt gaagtgactt ttgagagaaa aaataagtat aaaacagaag taatagagac
    36421 taaaaaagaa aatggcaagt ataaacttgg attatgggta agagataaaa tatctggaat
    36481 tggaactatg actttttacg accctagtat ggaaaagttc aaagcaatcg gtcatgccat
    36541 aaaagattcg gatactaatg aactattaaa gataaagcaa ggatatatat ataagccaga
    36601 acaattaaaa atagtaaaag ctagtaatga aaaagtaggt aaaataaaag gagattttaa
    36661 tgacagcaat ttaatgggta atttctcaaa taattcagag ctaggtataa gtggtaatat
    36721 tacagaaaac cataataaag agtttaatgt agcaaataaa gaaaagcaat taatagaagt
    36781 tggaaggccg caagatgtaa aaataggaga tgcagtaatt ctttttgagg ataaaaacaa
    36841 aaatataaca agctatgata taaaaataga aagtatagta tatgataaag gaaattatag
    36901 agatatggta ataaaagtag tagatgacaa gttattggaa tacacaggag gtatcgtaca
    36961 ggggatgagt ggagctccaa taatacaaaa taataaaatt attggtgcaa taactcatgt
    37021 ttttagagat aatccgaaaa aaggatatgg tatttttata gatgaaatga taaaattgta
    37081 ggtgaggcat taaaaaattt tattatttta tcaattatct aggaggaata taattttgga
    37141 gtgtcgaata tgctttagag tagataatta ggaagcaatt gtgtaaaaag tttagttttc
    37201 tgtaataaga agatgttttt taatgggggg atttttagtg gaaaaaatca aaatagtttt
    37261 agcagatgac aataaggatt tttgtcaggt attaaaagag tatttgtcta atgaagatga
    37321 tatcgatata ttaggcatag ctaaggatgg aattgaagca ttagacttag taaaaaagac
    37381 acaaccggac ttattaatac tagatgtaat aatgccacat ctagatggat taggtgtaat
    37441 tgaaaaattg aatactatgg atatacctaa aatgccaaaa ataatagtac tatcagcagt
    37501 aggtcaagat aagataactc aaagcgcaat aaatctagga gcagattact acatagtaaa
    37561 gccatttgat tttgttgtgt ttataaacag aattagagag ctagtttcta atagagttac
    37621 acaagttgag ccaaaaccta gaccagttca agagactcaa atgactagaa gtgattttgt
    37681 taagaatgta ggaaatatag agacagaaat cacaaatata atacatgaaa taggagtacc
    37741 agctcatata aaaggatatt tatatttaag agaagcaata aaaatggtta ttgataatgt
    37801 tgagctttta ggtgcagtaa caaaagagtt atatccaagt atagctaaaa aattcaatac
    37861 aacaccaagt agagttgaaa gagcaataag acatgcaata gaggttgcat ggagtagagg
    37921 aaaagttgac acaataaatc aattatttgg atatacggta cacaatacta aaggaaaacc
    37981 aactaattca gaatttatag caatgattgc tgataaatta agactagaac atagtatggt
    38041 taaataaaca agacataaaa agtaaggctt tttaattaag gcattggcta taaatgcgta
    38101 ttacaagcag cgaaacggta taaccactag ggttataccg tttcgctatt ttaataaata
    38161 taaaaatttt ctttattatt tgcttactat atcaatataa taattttatt atactatgga
    38221 tatagtatgt gtctttacaa gttgtaaact gacagtggtt tattttttaa tataaatatt
    38281 gactttgatg caggtaaact ttgtattttt aagcgtatta tggaatatgt taaataaaaa
    38341 aatgatgaaa tatagtattg taaatgccaa agatgcaaaa caaacttaaa acatttattt
    38401 tattgttaag taatgctata atataatgtg attttaataa tgatagtgga ggtttaaata
    38461 tgagagtcga ggcccctata aaagtagatc gaaaaaccaa aaaacttgct aaaagagttg
    38521 aaagtgggga aatagcagtt ataaatcata tagacataga tgaagttgct gcaaactctt
    38581 tagtagaagc taaaataaaa cttgtcataa atgcggctcc ttctataagt ggtaggtatc
    38641 ccaataaagg tccagggata ttaactgaaa ataatatact aataattgat aatgttggag
    38701 aagagttatt tgaagaatta aaagaaggag aaactataga agttgtagat ggaaagatat
    38761 atagaaaagg aaaattttta ggtgcaggag aagttttaga caagtatgag gtttcacacc
    38821 aaataaaggc tgcctatgag aatttagctg tagaattgga tagatttata gataatacta
    38881 tagattatgc taaaaaagaa aaaggattta tacttggaga agtagaaatt ccaaaagtga
    38941 aaactaatta tgctaataaa catgtattga tagttgtaag aggtcaggac tacaaagaag
    39001 atttaagtac tatgctttct tatatagaag aggtaaagcc agtattggtt ggtgttgatg
    39061 gaggagcaga cgctttaatt gagtttggat atactccaga tgtgattgta ggtgatatgg
    39121 atagtgtaag tgatgaagct ttaaaaaagg ctagtgaaat agtagtacat gcttatacag
    39181 atggaagagc accaggtctt aagagggttg aggaattagg cttagatgca gttgtatttc
    39241 ctgcgccagg aactagtgaa gatatagcta tgcttatcgc ctatgagtat aaggctgagt
    39301 taatagtagc agttggtaca cattcaaata tgattgattt tcttgaaaaa ggaagaaaag
    39361 gtatggcaag tactttttta gttagactaa aaataggttc aaagcttata gatgctaaag
    39421 gcgttaattt gttatacaga agtaaattaa aaataaagta catatgggca ttaatagcaa
    39481 cagcattatt tcctgtgttg gtagttgcat cattgtcacc aggagttcaa cagttcatac
    39541 aactaatgca attaaagttt agagtattat tacagatgta aattttagga ggataaatat
    39601 gcatattaat atgaaatatt atatagtcac tataggggct atatttatag ctttgggtat
    39661 aggcatgtta gtaggattta atttaaataa taatcaacaa ttaagtgaac aacaagcaaa
    39721 tataataaat gatttggatg ataagtttga tatcttaaaa gaaaaaaatg ataaacttga
    39781 cagtgactta gcaagtgtaa atagagatta tgaagaggca gttaatttta taaataaaaa
    39841 tgtagataag attttagctg gttcgctgaa tggtaaaagt ataggaataa tatctgctaa
    39901 tgaaaatgac gattatacaa aaaatataga agacataata aataaatcta atggaagcat
    39961 tgcatttaat ataatattaa aagaaaacat aacaaatcca gaaaagttaa aggaaatgtc
    40021 aactaaacta ggtacagatg taaaaaatgc aaatgatgca gttaattata taattgacac
    40081 tcttaaaaag gaagatgcaa gtgacatttt aacatatctt caagaactag atgtaataaa
    40141 gtttaatttt attggagata catatctaaa atatgattcc gttgtaatag ctggtggaaa
    40201 tgatgcaaaa gacagtacaa aacagtttga aaaaatagaa aaatttgtag tttcaaaact
    40261 taaatcagag aataaatatt tagtagaagt tcaaaataca ggagttaaaa cttcttatgt
    40321 agaactatat tctaaaaaca aagttgcaac tatagacaat attgatgaag gtataggaag
    40381 tatatctcta gcgattcttc tacaacaagg taatatagtt ggtaattttg gtagattgga
    40441 tactgcaact tcattgttgc catctattaa atagaaataa ttttaaggag agaaaaaatg
    40501 gattcttata taagtataat aataccagct tataatgaag aaagtagaat aaaatataca
    40561 ttagaaagca tattggacat taagcaaata aatgaaataa tagttgtgga tgatggttca
    40621 attgacaata ctgctaaggt tgtatctgag ctagaaaatg aaaagattaa attttttaag
    40681 ttagataaaa atagaggtaa aggatatgct ttaaattatg gtatcaaatt agcaatgaaa
    40741 aatgcagata ttataggttt tctggatgga gatttaggaa gttctgctaa agaagttgaa
    40801 aaattaatag tacctatatt aaatggtgag gcagatgtta caatagccaa gtttcctcct
    40861 gcaaagagaa aaggaggttt gggatttgta aaaggtttag ctaaaaattc tgtgtttgag
    40921 atgactggtg ttgagttaga tgcaactttg tcaggtcaaa gaatatttaa aagagaagtt
    40981 ttagaaaagt ttgatgaaat accttttgga tatggagtag aagttggaat gaccattgat
    41041 atattaaagt atggatttaa aattaaagaa gtattagtaa atatgactca taatgaaaca
    41101 ggaagaaatt taaaaggttt tattcataga gggaaacagt attatcacat aaaaaaggtt
    41161 ttaggacaaa aaaagaaaga atggaggtaa tatcttagtg aaagattata tactttatac
    41221 cattttatta ttaactggat tatttggaac ctatgctgta attccactat ttaaaaattt
    41281 attgataaat ggaaatgtac ttagaccaaa ctataaaaaa gatatgatac cagtaagtat
    41341 gggaattgta tttttgccta tgattgtaat caatggaata atacttgctt tctttactac
    41401 agaatttaag gatttagcgt atatatttat gtttatgttt ggtatgatat ccatgttttt
    41461 tgcagggata ctagatgatg tcattggaaa tagagatgta agtggtttaa aggggcattt
    41521 taaaagttta tttaaaggaa gtcttacaac aggaggtttt aaagctttat ttggtggatt
    41581 tgtagggctt atagtttctg ttgctatatc aaaagacata attgatataa tagtaaatac
    41641 actaataata gctctatcaa ctaatttaat gaatcttttg gatttaagac caggaagggc
    41701 aataaaagca tatttattca taatggtaat tatattttta acattgacag gatttgttca
    41761 agttcttcca ttacttatag taccaaatgt acttgcatac tttaattatg atttaaaagc
    41821 aagggctatg atgggagata ctggttcaaa cgtccttgga atatctattg gaatgctcat
    41881 ttcttttggg tatccattta acattagatt aggatggtta atatttgtag ttattatgca
    41941 tatattcact gagaaatact cattaactaa gataatagaa aaaaataaac tattaaattt
    42001 tatagataaa ttgggaaggt agtattatga taagcaaaag agtggggatt gttgaatcaa
    42061 tagtaagtca aactgaaact ctagatgata taagagtaaa tataaatgga gaaatacaaa
    42121 gggcatataa ttatcccaaa atatctggaa ctataaatat aggtgacgaa gtggttttaa
    42181 atacaacagc agtagaactg agcttaggta caggtggata ccattttgta ataactaatt
    42241 taaataatat agaatctact ttaactgaag gtggacatat aatgaaactt agatatacgc
    42301 ctcttcaaat aaaagtggat tctgttgagg aacaagaaag tatttatcat gataaatttg
    42361 cgaattttaa aggattagaa ggtctttctg ttgtagtagg gactcttcat agtatgttaa
    42421 ctccatttgc agcttcattt aaaagaaata atccaaataa aaaattagtg tatataatga
    42481 ctgatggagc atctcttcca atttatttaa gtaaaaatgt ggatacttta aaagaaaaaa
    42541 aattaataga tagtacaata actataggaa atgcgtttgg tggagattat gaatgtataa
    42601 atatatatac tgcattaatt acagcaaaag aaatactaaa agcggatgca gtatttgtca
    42661 gtatgggacc tggaattgct gggacaggaa caaaatatgg atttacaggg attgaacaag
    42721 gctctattct tgatgccgta aaaaaacttg aaggaagagc aattgcaatt ccaagaatta
    42781 gttttgctga caaacgagaa agacatcaag gtatttcaca tcatagtatg actgtattta
    42841 aagaaattgt aaatgtaaat gtagacatac caataactat atatgatgat gaaaaattga
    42901 actttataaa agagcaaatc aatttaaatg gtttagacaa aaagcataat ataatttata
    42961 tagataataa taaaacgaaa gaggatttag actattttaa tctaaaagta aagagtatgg
    43021 gaagaaatta tgaacaagat gaggcatttt tcaaagctgc aagcacagca gcatattact
    43081 taatggaggt ttaagatggt attagaagaa aaaactatta gtagtgatag ggtttataca
    43141 ggtaaagtaa ttactttaaa ggttgatact gttgaaattc cagggcaagg atatcaaaaa
    43201 agggagttag tagaagttgg tggagcagta ggaatagttg caatcacaga tgataataaa
    43261 gttgtgttag ttaagcaatt tagaaaacct atagaaaagc caatctttga aattccagct
    43321 ggtaaactag aaaaaaatga aagtccaaaa gaatgtgctg aaagagaatt aaaagaagaa
    43381 actgggtata gtgcaaaaaa tattaagcta atacataaat ttttcacttc agcaggtttt
    43441 tctaatgaga taatgtttgt atatttagca acaggtctta ctccaggaga gaataattta
    43501 gatgcagatg agtttttaga tgtctatgaa attgagcttg aagaagcata taacatggta
    43561 ttaaaaaatg acgttgaaga tgcaaaaaca tctattggat tattattagt aaaagatatg
    43621 tttaaaaatt aatatttata aaatgaataa ccctttgtcc taaagcatac tattttataa
    43681 aggacaaggg ggaattaaat tgagaagaac atatagaaaa aatgatttta gagaattaaa
    43741 tagacaaata attattatag gattgttgtt tatgatgtct attgttattg ggtcttacat
    43801 aaataaaata ttgccaggtt ctagtaacaa tatattaaac aatataaatc ctgctgtaga
    43861 gtattataat ctaaatataa gcataaaaga tacagtgata caaaatttaa aatcagatgc
    43921 aatctttatg ggctcaatag ctctattaag tctatttgta gtaacaattc cagcagtgtt
    43981 ggtagctttt gtattaaaag ggatgtcaat tggttataca ataaatagct gtatattggc
    44041 attaaaattt aaaagtataa aaatgatttt aataatatta tttaaaaatt tgattattat
    44101 tccatgtgca atcatattag cattaattag tttaagttat tttaaagaaa tggtttatga
    44161 atttaaaaag aaaaatagaa aaaatatgca atttttaatt aagaggtata tactaaatat
    44221 tataattata atagcactat cattggggtt gcaattaata ttaaatactg caagtattgg
    44281 tattattaag ttcctagcta aataaaggag tttataatgg atattataga gggatatata
    44341 gattacataa aagataaaaa aaaattatca gagaatacag tggcatcata ctttatggat
    44401 ataaaaaaat atatggaata tataaatcaa aaaagcatta aactagtaga tatagtagaa
    44461 aatgatatta taagttactt aataaagttg gaaaaagata atgtatcaat agctacaata
    44521 gcgaggatga tatcctctat aaaatctttt catgattatt tatttttaaa tcatatatgt
    44581 gcaaataatc ctgcaaagga tataaaaaaa cctaaaataa aaaaagaaaa tataaatata
    44641 cttacagaag aagaaattga aagactatta aattttccaa agttaacaac gcctaaattg
    44701 attagggaca aggctatttt tgaagtatta tatggtactg gtataaaagt atctgaatta
    44761 gtagagatga atatagagga tattgaccta gatattgatt atatatattg taattcatgt
    44821 tgtaaaaatc aaagagtgat accactttgt gatattacaa aactttactt agaaaagtat
    44881 ctaaaagaag caagacctaa aatggctgta gaaggtgaaa aatcattatt cgtaagttca
    44941 ttaggtcaaa ggtttacacg acaaggtctt tggaaagtca taaaaaaata ttctaatcta
    45001 gccaatatag ataaaaatat aaatcctaca atgcttagac attcatttgc tattcatttg
    45061 ttaaatgaag gtgctaacat tgctgttgta agtaaaattt taggaaatgt taatttatct
    45121 agtttgcaag tatatttaaa tcatatagat aaaaacgtga gaagagaaat aaaggagaaa
    45181 catcctagaa atgatgttga tgtagaatta caaaaagcag aagctaaata gactatatag
    45241 caaattttat aatttagaag gagcatattt atatgagcag agtaatttgg attgtaattg
    45301 atagtgttgg gataggagca ttgcctgatg ctgaaaaatt tggtgatagt aaggatgtaa
    45361 gtacccttgg aaatatattt aaggaatatc cagatattca gattcctaat atgagaaatt
    45421 taggtatagg aaacatagat ggtatagatt tttttgaaag tataaaagaa ccaataggtt
    45481 gttttggaaa gtgtaaggaa atgtctcagg gaaaagatac tactacaggt cattgggaaa
    45541 tgactggtat aatagttgac aaaccattta agacatttga acatggattc tctaaggaga
    45601 taatagaaga gtttgagaaa aaaactggaa gaaaagtagt aggaaataaa ccagcttcag
    45661 gaactgtaat aatagatgag tatggagagc atcaaataaa aactggagat gtaatagtat
    45721 atacatcagc tgatagtgta tttcagattg ctgctaatga agaagtaatt cccctagaag
    45781 aactctataa tatgtgcaaa atcgctaggg aaataatgat gggggataat gcagtagcta
    45841 gagtaattgc tagaccattc ataggtaaga aaaaaggtga gtttgtgagg acttcaaata
    45901 gaagagatta ttcactagac ccatttgaac caacagttct tgataatata aaagaatcag
    45961 gacttgatgt tttagcagtt ggaaaaatag aagatatttt taatggaaaa ggaattacag
    46021 atgctatcca cactaaaagc aatatggatg gagtggatga aactttaaat tatatgaaac
    46081 aagataataa aggtctaata tattcaaatc tcgttgattt tgattctaaa tatggtcata
    46141 ggagagaccc agaaggatat aagaaagctc ttgaagagtt tgatagtaga cttcctgaaa
    46201 taatggctaa tatgagagaa gatgatattt taataatcaa tgcagaccat ggaaatgacc
    46261 caacatataa aggtacagac catacaagag aatatatacc tgttatgatt tatggcaata
    46321 agattaaaaa aggttttaat ttaggagtaa aagatacttt tgctgatatt ggagcaactg
    46381 ttgcagatat actaaatgta aagttgccta aacatgggtc aagctttaaa gaagatttat
    46441 tttaaactat aaaatgataa aaacttagct taataggatg gagagattgg aatgtttgaa
    46501 aagatagcac aaagtagtaa atttataaat tctaaaagta atataaaacc taagattggt
    46561 ttgatattag gttctggact aggtgattta gcaaatgata tagaagaccc tgtcacaatt
    46621 aaatatagtg aaattccaaa cttccctgta tcaacagtag caggacatgc tggacaactt
    46681 gtaattggaa aacttgaagg aaaagaagtt attgctatgc aaggtagatt tcattactat
    46741 gaaggatatt ctcagaaaga agctactttt ccagtaaggg ttatgaaaga attaggagtc
    46801 gagattctta tagtaactaa cgctgctgga ggcgtaaata aagaatttaa agcaggagat
    46861 ttgatgctta taagagacca tataaacttt agtggaagta atccattagt aggaaaaaat
    46921 gatgacagat ttggtgctag atttccagat atgtcagatg catattcttc taaatatgta
    46981 gatgtagtta aaaactgcgc taaagaatgt aatatagatg tcaaagaagg cgtttatatg
    47041 ttttttagtg gtccaaacta tgaaacacca gcagaagtga gaatggcaca aattttggga
    47101 gctgatgctg taggtatgtc tactgttcca gaagtcatag tggcttctca ctctaatata
    47161 ggagttattg gtatatcttg tataacaaat atggctgctg gcatcttaaa tcaaccacta
    47221 agtcatgagg aagtaataga aactactcaa aaagttaaat cagaatttat gaatttagtt
    47281 aaaacaacgg ttaaaaattt ataagttaaa gcttattata gattttttga ggaagtttat
    47341 aataaaatag ttaatgttta atttgaaaag aattaataaa aagctgtctt gatatagaaa
    47401 gttatttcta ataaaggaca gtttttttat aatactacaa catttgaaag tgttttaaag
    47461 tttaatattt atttaaatta ttataggtta gaatggagat ttcaattatg agaatgtatg
    47521 atattataaa aaaaaagaga gataacctag agcttagtaa aaaagagata aactacttta
    47581 tagaaaacta ttcaaaggga gatacacctg actatcaagc ttctgcacta ttaatgtcga
    47641 tttacttaaa taagatgaat aaacaggaaa ctgtacatct tacagaagca atgatgaact
    47701 ctggagacat gataaaccta tctgagatag atggaataaa ggtagataag catagtactg
    47761 gtggtgttgg agataagact accatagctc ttataccttt ggttgcttca tgtggagcac
    47821 cagttgcaaa gatgtcaggt agaggtcttg gtcatactgg tggtactatt gataaattgg
    47881 agtctatacc aggtttttcg acagaaatgg agataagtaa atttattgat tctgtaaata
    47941 agtctaaaat agcagtttgt ggtcaaagtg caaaggtagc aattgcagat aagaaaatat
    48001 atgctcttag agatgttaca gcaactgttg ataatatatc attgatatca tcaagtgtaa
    48061 tgtctaaaaa gttagcttca ggagctgatg caattgtgct agatgtaaaa actggtgatg
    48121 gagcatttat gaagacatta gaagagtctt ttgagttagc taaatctatg gttgatatag
    48181 gtactggtat gaatagagat acaataggga ttgtaacaga tatggatgaa cctttaggtt
    48241 ttgcagtggg aaactcttta gaagttatag aggcaattga gacattaaaa ggaaatggac
    48301 ctaaagacct tgttgagcta tgcgaagtat taggagcata tatgttggtt ttatcaaagg
    48361 tagcacatga ttttgaagat ggtgttgaaa aaataagaga atcaataaaa tctggtactg
    48421 ctatacaaaa actcaaagag tttatagaga atcaaggtgg taataaagat gtagtagatg
    48481 attattcttt attcaaaaaa tcaaagtata aatatccagt taaatcaact aaatcaggtt
    48541 atataagcaa aattaaagct gaagatgttg gtgtatcggc tatgattctt ggagcaggta
    48601 gagaaactaa agatgatatt ttagatttat cagcagggat aattttagaa aagaaagtag
    48661 gagattatgt aaatgaaggt gaagttttag cttacatgta ttataatgat gaacaaaagc
    48721 tttcattggc aaagggaaga tttattgatt cctactctat tgtagattca aaaatagaaa
    48781 aaaataaatt aatatatggt attgtaacta aagaagagat taaaaagttt tagaaaagtg
    48841 attataaaag gcctaacatg tcaaaaataa tgttaggttt tttatttttt gataaactat
    48901 aaattatacc aaaaatatat attttaaaac attttttaca atataaataa gtttattcta
    48961 caagatgatt gaaaattaaa gtatctagtt ttataataga aaatggataa atatacataa
    49021 ggagtagatt atattatgaa ctttaaagaa aatagattga aaatagcagt attaataatt
    49081 gttattttga ttatcttagc aggtatattt gtgtttatac aaataggtcc ttatgataaa
    49141 aataacaaaa aagatgtaat tatcgacgtt ccaagtggag catctgttgg aaaaatatct
    49201 gacatattat atgaaaataa attaataaag aatgaactat tatttaaact tttggtaaag
    49261 gttagcaata aagctccgtc tataaaatca ggaacatact tacttaatca atcgtattca
    49321 aacaatgata taataagtct tttagtttca ggtaaaatat atcaggatgg tataaaagtg
    49381 actattccag agggagctac atctaaagaa attatagcaa tgttagtaag taaaaattta
    49441 ggagataaag ctacttttga aaatttaata aaaaaacctc aagaatttta tgataaattt
    49501 ccatatttga aggaagatgg aataacctct ttagaagggt tcttgtatcc agaaacttat
    49561 tattttaatt caaagaaaca atcagaagaa gatattttaa gcgaaatgtt aaaagtattt
    49621 gacagtaaat acacggacaa gtttaaaaag aaacaaaaag aattaaatat gactcttcaa
    49681 gaagtaatgg aaatggcatc aataattgag aaagaagctg ttcttgacaa agacagacct
    49741 ataatagcaa gtgtgtttta taatagactt aaggtaggta tgcctcttca atcagatgct
    49801 acaatacaat atatatttga agagagaaag aaaattgtaa catatgatga tttaaaaatt
    49861 gattcaccat ataatagtta taaaaataag ggattacctc ctacaccaat atcaaatcct
    49921 ggtataaaat ctattgaagc agcattatat ccagagaaaa cagactattt atattttgta
    49981 gctaagattg atggtggaaa taattatagt acaaactatc aagaccattt aaaatacgtt
    50041 aaagaatata aagaagcaag ggataaacaa tcaaaagata caaaagcaac aaataaagaa
    50101 aatacaaaaa aataaaccat gattataaaa agtctaacag ggtaagaata atgttgggct
    50161 tttttattga aaattgttat tcttagattt ataataaaga aagtgtaaat atatataaca
    50221 atatgaattt aaaaaataat aaattaatat aaaacttgaa tatttattat tttagggagt
    50281 gtttttatga gtaatatagt taatgatttg gttgaagatt atataagagt gacattaaaa
    50341 gaaaaagaag gatttttaaa agatttagaa atttatgcag aggaaaatag tgttcctata
    50401 atacataaag aagtttcaga tttattaaaa gtcttgttaa aggttcaaaa accaaagaga
    50461 attttagaag taggatgtgc aattggttat tcttctattt tttttgcaac tattatagga
    50521 aaagatgcag atataataac tgttgagaga aatgaaaaaa tgatagaaaa agcaaaagaa
    50581 aacataaaat tagctggatt tgacaataac ataactatac tagaaggaga tgcagaagaa
    50641 aaacttagtc aagtccaagg tgaatttgac cttatattta tagatgcagc caaaggtcaa
    50701 tataagctat tttttgattt agttatagat aaattaaaag atgggggact tttagtatct
    50761 gataatattt tgtataaagg tatggttgct catgatgatt ttgttgtaag aagaaaaaag
    50821 actatagtta aaagaatgag aaattattta gattatatat gtaattgtga ctatttaagc
    50881 acatcattgg taccaatagg tgatggtgta gcactaagtt ataaagaaag taaaagaggt
    50941 gatgtagatg gaattaaata aagtagaact tttagctcca gcaggtgatt tggagagatt
    51001 gaaaatagct ataacatatg gagcagatgc cgtttatata ggtggagaaa tttttggaat
    51061 gaggtctgca gcgaagaatt ttagtaagga agatatggca gagggagtag cttttgcaca
    51121 tgaaagaggc aagaaagtat tcgtaacagt aaatataata cctcataatg aagattttct
    51181 acaattagaa gactatttgt tggaactaga agagatagga atagatgcag ttataatagc
    51241 tgacccagga gtgcttagtg tcattaaaaa agtaattccg aatatggaaa tacatttaag
    51301 tacacaagca aatacaacca attatctaag tgcaaacttc tggtacgagc atggaataaa
    51361 aagagttgta gtggcaagag aattatcttt tgatgaaata tctgagataa gagcaaaaac
    51421 acctttagat atggatatag aagcgtttat gcatggtgct atgtgtattt cttattctgg
    51481 cagatgttta ataagcaact atatgactgg aagagatgca aacaaaggtt cttgtgctca
    51541 atcttgtaga tggcaatatc atttggtgga agaaaaaaga cctggtgagt attttccaat
    51601 atacgaagat gaaaggggta cattcttctt taactcaaaa gatttatgta tgatagagta
    51661 tataccagag ttaatcaaat ctggtataac aagtttaaaa atagaaggta gaatgaagac
    51721 tgcatactat gtagctactg ttgtaagagc atacagaatg gcaatagatg aattttacag
    51781 agacccagaa aactggaagt tcaatccaat gtggatggaa gaactaaaaa aaggtagtca
    51841 tagacatttt acatcaggtt tttacttgaa taaaccaaca acagaagacc aaaattatca
    51901 atcagcatca tatgttagaa actatgattt tataggtata gttagagaaa cagaagatga
    51961 agatggtctt attgttgttg agcaaagaaa taaaatgtgt gttggtgatg aaatagaagt
    52021 tatgggacca tataaagaaa ctatgtttac taaaattgaa gaaatgtaca atgaagaagg
    52081 agaagctata gaatcagctc ctcatcctag acaaatagtg aagttaaaac tatcagtaaa
    52141 agttggtaaa gattatatgc ttagaaaagt tatagaagaa aaggttgaag aataataaaa
    52201 aattgataaa aatagtatta gccccttaga aattgtcaat aatgaaatta tctaaggggt
    52261 gatttcatgt caaaaaagaa gactccattt ttgaaaaaag tgggaaagag aagctggtgt
    52321 atatttacta taattttaat aatttatagt gttttaattt ataggctagt tgatatacaa
    52381 gtattaaaag gtgataaata caaacaaagt gttgaatcac aaagcgttga gaaagtcgag
    52441 ttaaatagtg gaagaggaat aatctatgat agaaacaaca agaagcttac agatacaagt
    52501 aaatctcaga tattaattgt tgaaaaagaa aaattaaata ataactataa aattttggaa
    52561 cttattaaga aagctactaa gatgaatgat ttagatatat ataaagctgt acaagagcaa
    52621 ttgacacgcc ctataataca gattcagact aaaaatatcg ataagagtat gaaaaaagaa
    52681 cttgagaaaa atggaataat ggtagaagaa aaaactatga ggtacgcaaa agatggttta
    52741 ttatcacata caataggata tataaaagaa gatgataaat caggtcaatc aggaattgaa
    52801 aagagtatgg atagtgtact tagaaattca aatgaaaagt atataagtgc ttttaaagct
    52861 ggagatgcag gaaatgaaaa atctctaaac atactaaagg gaagtgtaaa aactgttgat
    52921 aataaggata aagatagaca tctaaaaact actattgatt ataacattca aaaaaaatta
    52981 gaacaaatac taaataaaga agaaaatcct acagcagcaa taatctcgga agcatctaca
    53041 ggtgaaattc ttgcaatgtg ctctagacct aattttgacc aaaatgacat atcaaaaagt
    53101 ttaaaaggaa aaaatggaga atttgaaaat agagttataa aagcgacata tccaccaggg
    53161 tctgtattta agatggtagt tttattttct gcacttgaaa atggtgttat agatgagaac
    53221 tatacttaca actgtacagg taagactaaa gttgggaata ctaatgaaat actgcgatgt
    53281 aataaaagag atggtcatgg ttttcaaaac ttaagacaag ctttttctaa ttcatgcaat
    53341 cctgcatttt tagatatagc tatgaaactt ggaaaagaaa agatactcaa atctgctgaa
    53401 aaattacatt tatttgaaaa ggttgatatt ggtcttgatg aagaaaaaat tagagaagct
    53461 ccaaaaaaca tatcaataag aaatttagct ataggtcaag aaaatataga atttacacca
    53521 cttcaaataa atcaaatgac tcaaataata gctaataatg gaacattcaa accactatac
    53581 ttatataaaa gtcttgtgga caataatatg aatacaataa aaacttataa gtcttcaaaa
    53641 aaagaagaac ttatttctcc ttatgtgtgt acacaagtta aagaatatat gaagtctgta
    53701 tctaggactg gtacagctaa agacctaaaa gatattgaag gtggttgtgg agttaaaact
    53761 ggtacagctc aaagtagttt aaataaaaaa gctatagacc acggatggat aacaggattt
    53821 tatcctgaag aaagacctaa gtatgtaata actgtgttag tagaaggaac tcaaaaagga
    53881 aataaatctg caacacctat atttaaggaa atatgtgaaa gtataaaata aattatgtac
    53941 tataaaattt aaggatatat cgtaactttg attttagata gaaaattttg tctaatgatg
    54001 tacgatatat ccttttaaaa tatagtatta actttcttga acaagctctt tttctagttt
    54061 tttaagagct tttttttcga ttctagatac atatgacctt gatatatcga gtttttgtgc
    54121 aatttctctt tgtgtcttat agccataagg agttaaccca tatcttaact ggacaatttc
    54181 tctttctcta ggagtaagaa ttttgtttag ttgttcgtaa agttttccaa cttgaacttt
    54241 tagttcaact tcatcaagaa catagttagc ctctgtacca agtatatcta aaagacttat
    54301 ttcattacct tctttatctg ttccgatagg gtcttgtaga gatacttgag ttttattttt
    54361 tttgttagat ctaatattca ttaaaatctc attttcaata catctagaag catatgttgc
    54421 taatcgagtt cctttatcta tgttataagt ttctatagct ttaattaatc ctattgtacc
    54481 tatggatatt aaatcatcct gatcttccgt tgaattatta tatttctttg ctatataagc
    54541 tactaatctc atgtttcttt caattaatgt atcttttgca cttttatcgt tttctatttt
    54601 aaatttagtt aaatactcaa tctcttcttc aggggttaag ggtttttcaa aagatttaag
    54661 agctgccaat aggtcacccc cttttcaacg gtcactttaa attatatgaa ggagacttat
    54721 ccaagttgac tgttatctaa taaaataata tgcatatttt tagaatttaa aacatatatt
    54781 tgcaaacttt tgaatggaat atgacataaa gagtgggaat ttaaatttaa gtttttgttg
    54841 tatatatatg aaacaaggcg aagaaattat tgatttataa agtataaatt ggaattgagg
    54901 tgtcaataaa tataaaagga aatagtattt atatatgttt tggtgttgaa gtaaaagatt
    54961 aatgcaaagt attagagtct ataaaaatat gaatatagga ggtgtaattt tacaatattt
    55021 aaaaaagtaa atgtaattaa ttgtttgtat aaagttgatt acaagcaaaa gtatcagtca
    55081 tagttaatac tgttaaggat gaaggtggtg tgttaattta tatatgtatg ggaagaaatt
    55141 ttgattacaa tgaaaaaact tacaaaagat atttacaaaa aaacttatag ttaaatgttt
    55201 atatataaaa tactatttag gggttgtttt tattattgaa aataagaaag agtggtttta
    55261 tatcaatcga atgtataata agtattgcta tattatatgt ggctgtttat ttagtttcta
    55321 catcattgta taattgttat agttttatca gtagaaatat atctgacaga gaaatgttaa
    55381 gtacagcaaa aaaatatata gaagatgaga agtatagaat acaaaatagt aagtatgagt
    55441 taattgaaga taagatagaa aaaaattaca taaatggata tgaaattaac agtagaatag
    55501 agcaaatttt agattattat caatgctatg aaataaatat agagataaaa aatgaattta
    55561 aaaaactgag gtttaatagc tatgttacta gaaaataaag gctctatatt aataataaca
    55621 ttgataatat tttctattat aagtactgtg tgcattatgt gtataggttt aatttataca
    55681 cataataata tgtttgagtt aggatacaaa gacattcaac taaaagaaat ttctttaagt
    55741 ggaatagaaa tatcagtaag taatgtactt tcttgtgttg aggaagctat tgatgtatct
    55801 aataatgaag acgaatttag agaatatttc ttaggaaata atatgattga atgtataaaa
    55861 aaaataaaag atacatctta tagtagttta gaagaacttt ctttaaaagt agaaaataat
    55921 actatttatg acagaggaga tttttttgaa tttgatatag aaagtaatgt tagagaaaaa
    55981 gaatttttaa aagcaataaa agtaagagtg aaaatcaaaa atccatggat aggaattgac
    56041 attgaagatt atatggataa atctaataac aataaaattg atgacaaaac attcaataat
    56101 tataaagcat ctgaaaataa tgaaattcta aatcaattta aaaatgaaag tgaaaatata
    56161 aggaatcaag aggttggtgg atttacagaa gaagatgaag aatatgaaga agaacttaaa
    56221 caaaacataa ttgaaaatat aaagaagaat tttgatgaaa aaaacctagt acaggtatat
    56281 aagtataggg gtgtataact ttgaaaaaag aaggaatgtg actgtaatag aattaatagt
    56341 atctatcagt ataatactct tgatagttac attatctttt ccaaaagata atcttgaaaa
    56401 tcataaaata aatttatttg cacgtcaact ttgttcagat ataaggtatg ttaggcgaat
    56461 taatatgttt agtaactaca atacatatat atattatata aatcaaggta aacacgaagg
    56521 ttatgtattg agaaaagatg gtaaaaacat taaatcaata atgctaccta aaaatgcaaa
    56581 aatagctagg agtattgaaa taataaagtt taaatctgat gggtcgcctc aaaaggcgtc
    56641 tacaatagag atatataata atagattaag aaaaactata acaataacac ctgtaagtgg
    56701 aagagtactt ctgaaagagg gaaaatatga aacataaata tggttacttg cttttggaaa
    56761 gtgtagtatc attgtcttca atggtgataa ttatactagt tttatattct atatttttgt
    56821 ctacaataaa cttaaagtta aaagtagaag ataagataga actacaacaa caaagtcttg
    56881 aaatcataaa atctatggaa ggaattattg gcaattctat gggaataatg aatatatcta
    56941 attatgaaga aacatttaaa aagacaacgt ctataaaatg tagatatgta gatgaaaata
    57001 ataatgaaga aggcataagt aataaagaaa ttatattgaa tgaaagacga aataagttat
    57061 ttgtaaattc tttaaatggc gaaagtagtc aagcaggtgg ttatgaaatt ggagattatg
    57121 tagatgaaat gtatgtatca attactaata atggtcaata tgttaatatt aaattgaaat
    57181 tatcaaaacg tagtcaaaaa tatgagactg atttcaaaat aaaagtatgg aattttagtg
    57241 aaagtatata aaaatacata aatttaagag aaagaaatga catcaataag tcatataaaa
    57301 tataattatt gagaactata taactaaata atatcaatat gtaaagtgta tagattaaga
    57361 atatagagga taataataaa aatatagaat aagtaatttg ccaaatactt gtttatattg
    57421 tataacttat gatattatga tattagtaaa aatttgtaat cctgacttga cagaattcaa
    57481 gtaagagata taattttaaa ggcatagtaa tgtaaaattt actaaaaaat aagaaattta
    57541 ttttaatatg gaggaacaaa aaatggtatc agcaggtgat tttagaaaag gtgttacatt
    57601 tgaaaaagat ggacaaccat gtttagtagt tgattttcaa cacgttaagc caggtaaagg
    57661 agctgctttc gttagaacta aatacaaaaa cttaaaaaca ggagctataa gagaagaaag
    57721 tttcaatcca agtgaaaaat tccctaaggc tgttatagat acaagacaaa tgcaatatct
    57781 atacaatgat ggtgagttat attattttat ggatcaagaa aattttgaac aaataccatt
    57841 aaactatgag caagttgaag atgcaattaa gttcttaaaa gaaaatgaag ttgctacaat
    57901 aagattttac caaggacaac cattccaagt ggaagcgcca aactttgcag agctagaagt
    57961 tacagataca gagccaggta taaaaggtga tacagcaagt aatgtaacta aagcagctac
    58021 agttgaaact ggagcagttg ttcaagttcc attatttata aatactggag ataaagtaaa
    58081 gatagatact agaacaggtg aatatttatc aagagtataa aaatttatgt atataaaagc
    58141 ttatatgtct taataatata agatatatga gcttttagtt tatatataaa aaagaaagcg
    58201 aggggtgtta catgaaacat ttatatgaag aagttgcata cttaaaaggc ctagcagaag
    58261 gactagaaat aagtgctgaa agtaaagaag ggaaaatgat acataaaata gttgatgcat
    58321 tagaagtatt tgcagatgct attgtaacat tggatgaaga acaagaagaa cttcaagatt
    58381 ttgttgaatc tatagatgaa gatttagcag atttagaaga agatattgct gacatggaag
    58441 aagatcttta tgaagaagat gacgatgagg atgatgagga cttcagctat atagaaatgg
    58501 aatgcccaaa ttgtggagag ttagtagaaa tagacgaaga tttgttatat gatgatgaag
    58561 tagatgttgt ttgtcctgat tgtaaggctg tgatattatc atcagaagat gattgtgatg
    58621 atgattgtac atgtggtggt tgttcaagtt gtgatgatag agagtaaaaa ttcataagaa
    58681 ttaaaactgc ctatgatgcc tatgagatat tttgcttcat aggtagtttt atttttatga
    58741 ggaagggtat tatgtatttt ggttttgcaa tacttggaca aaaatagtac actagaattt
    58801 atagaatagg attttggagg gatgtaaata tgaaaataag taaaaaatta ctagataata
    58861 tacaaagatt tgaaaatgtt ataaattata aatttaaaaa taaagaatat atactagaag
    58921 ctcttactca tagttcatat tctaatgaaa ataaaaaata taattttaac gaaagattgg
    58981 aatttttagg ggattcggtt ttaggcatag tgataagtga ttatttattt aatgaagaag
    59041 ctaatctgcc cgaaggggaa ctaactaaac ttagagcaaa tatagtctgt gaagattcat
    59101 taagtgaagt agctaatgat ataaatttag gtattcacat gttattaggt agaggagaag
    59161 aagcaacagg aggaagacat aggacttcaa tattagcaga cgcatttgaa gctgtaatag
    59221 ctgctatata tcttgatgga ggttttgaaa gtgcaagaca gtttatactt catcatatgg
    59281 aaaatataat ttatgattca agaaaaggaa atatatttag agactacaaa acgcatcttc
    59341 aagaggtgtt acaagggaat ggagaaaata atatctggta caggcttata gaagaaaaag
    59401 gaccagacca taataaaaga tttgtaatgg aagttggaat taatgacgat gtacttggta
    59461 taggagaagg caagagtaaa aaagaagctg aacagttagc tgctaaaata gctttaaaga
    59521 aaaaattatg ggaaaaataa atataatatg taaaaatata aaaagaaata tttatattag
    59581 aaggatgttg tagatgaaaa agagaattat acctatattt gttcctcaca aaggatgtcc
    59641 tcatgattgc atattttgta atcaaaaaaa aataacaggt gtgagtactg atgttactag
    59701 tgaagatgca agaaatataa ttgaggaatg tttagagact atagataaag atgcagatgt
    59761 agaaatagca ttttttggtg gtagctttac tgctatagat attgatatac aaaaaagttt
    59821 attatcagtt gctaaagaat atgtagaaaa aggtcttgta aaagatatta gaatgtctac
    59881 aagaccagat tgtattgatg aagatatatt aagtatgtta aaagaatata agacaagtat
    59941 aattgaacta ggagtacaat ccttagatga aaaagtatta ttagatagta taagaggtca
    60001 tcaatctgaa attgtataca agagttcaaa gatgataaaa aatagtggaa tcaaacttgg
    60061 attacagatg atgattggtc ttccagctga cacagaagaa aagtgtatat ttacagcaaa
    60121 aaaatttgta gagctaaaac cagattgtgt tagagtctat ccaactttgg tagtaaaaga
    60181 tacaggtctt gaaaagttaa tggaacaaaa taaatataat ccatttactc ttgaagagag
    60241 tgtaaatata gtaaaaaaag ttcttgtact gttttatgtt aataatatca atgtaataag
    60301 agttgggctt caagctactg atgatataca aattggaaaa gctgttttag caggaccata
    60361 tcatcctgca tttagagagt tggtagaagc agatatgata aaagattatt tagaatttgt
    60421 tatttttcaa aataaaaata taaagcaaat gttggtcaaa tctaataaaa agaatatttc
    60481 taaaatcata ggaaataaaa aaacaaatgt taaatatatg gaagaaaaat ttggtgtgct
    60541 tttaaaaaca caagaatcag atttagatat aaatcaatta gaaattgtgt tagatgggaa
    60601 aagtttaatt agtgctaata tgagagacat tcatagaaaa ttgtatgaca tttatgacct
    60661 ttagttttaa taatgaaggg agagaaaaga tttgtattta aaaagactag agttaaaggg
    60721 atttaaatcc tttccagtaa aaacagatat tatttttaaa gaaggaataa cagccatagt
    60781 aggaccaaat gggagtggaa aaagtaatat atctgatgct gtaagatggg tattaggaga
    60841 acagagtatt aagagtctta gaggggataa actcgaagat gtaatatttg caggtacaga
    60901 tacaaaaaaa cctatgaatt attgtgaagt ggctcttact attgataatt ctgaaaatca
    60961 attggaatta gattttacag aagtaactat aagaagaagg gcttatagaa atggtgaaag
    61021 tgaatttttt ctaaataata aaagttgtag attaaaagat ataaaagaag tctttttaga
    61081 tactggtatt ggaaaagatg gttattcaat catagaacaa ggaaaagtag atgaaatatt
    61141 aagtaataat cctttaagca gaagaaaagt ttttgatgaa gcttgtggca tatcaaaata
    61201 tagatataaa aaacaggaag cagaaaggaa tttaagtaat acaaaggaaa atttagaaag
    61261 aatagatgat gtatatatag aaattgaaaa tcaattaaag cctcttttta atcaacagac
    61321 aaaggcaaaa aagtacttgg aaataagtga aaaattaaag acacttgaag taaatagctt
    61381 tataagagaa attgaaggaa tagaaaaaga attaagtgag gttaatgaac atcgtaatgt
    61441 tattgaaaag gagctcaatg aaaaagaaga acaaaaaaat gttgtagaga aaaagcaaga
    61501 agatattaat aaagaggtag aggtattaca agatgtaatt gaaaaatctg tagattatat
    61561 aaattcaatt aaaggagtta tatcaaaaaa agaatcccaa ataaatttaa ttaaggaaag
    61621 aataagaaat tttacgaatg aaattagtag aaaaaattta gaaataaagg atataaaaga
    61681 gaagctaaat gaaaataagc aatacataaa agaattagaa agcaataaat tatcaggtag
    61741 tgaagaacta tctaccttgc aggaaaatat aaaagtattg gaaggaagta aagataaaca
    61801 aaaaattaag ttagaatccc taaataatga gatagaatta ttgaaagaaa gtataattga
    61861 tatattaaat aagaaacaag agtttagtaa taagctgtct actttaaacg caaataaaga
    61921 aaatatgaat atcagagatg aaaatataaa ttcagagata acagagttaa acaaaaatat
    61981 tgaaataaaa tcatctgaat tagatactat aaataaagaa tttaatatgc aaaatgaaaa
    62041 tttaaagaat gtaaataata gacataaaga attatcaatt aatttgcagg attcaattag
    62101 tgaacacaat aaactagaag atgaaataca gaaaagtaaa tataatttaa atggatataa
    62161 ttcaaagtta aatgtctata tagatatgga aaatcattat gaaggattta atagaggagt
    62221 aaaagaagta ctaaaaaata aaaatttaaa aggagttcat ggagcattag gacagattat
    62281 aaatgtacct gaaaagtatg agaaatctat agaagcagct cttggtgctt atatgcaaaa
    62341 tataataact gataatgagt ttagtgctaa gtctgcaata aactatctaa aacagaataa
    62401 tttaggtaga gtaacatttc ttccattaaa tataattaaa tcaaataaaa taagtctagg
    62461 aaatttaaaa gcaaatacta agttcatagg aatagcaagt gatttaatta catttgatga
    62521 aaagtataga aatataattg aaaatatact tggaagaaca atacttataa ataatataga
    62581 tgagggcata aaatttgcaa aagaaactgg tcataggttt aaaatagtaa ctttagatgg
    62641 tgaaatctta aatccaggag gttctttgac tgggggaagt ctaaaaacta atgggaatat
    62701 actatcgaga aaaagataca ttaatgaata tacagaaaag ataagtaata tcaagaatca
    62761 aatttcacat ctagaattaa aaagagaatc tttagacaaa gatgtgaaaa atatcaaaaa
    62821 tgaaattgat tcacatgaaa gtaaaataaa agatttagaa aaaagtataa taataaaaag
    62881 tacaagtata aagaatgttg agtctgaaat tgaatcgtta aaaggtagta ttactaaatt
    62941 agaaaatgag aagaatgatt taaattctaa cctaaattat acacttgaaa aaagtgatga
    63001 tgttagaaaa gatatggaag agttagatga tttatacaat aaaaataaag aaaaaattga
    63061 tgcattgaat gaggaaataa aaagatacaa tgatttatat gataaagaaa aatctgaatt
    63121 tgatgaattg aacttaagtt tagtgaagaa aacagaagtt tacaatagta tagttagaga
    63181 tataaaaaga atatctggtg aaaattgtga gctagaagaa aaaaataaac aattagaaga
    63241 gtcattaaat tatgaagaac atgaaataat taaattacaa gattctatac tcactgaaga
    63301 aaaagaaaaa gaaaatttaa caaaacaact aggggatagt aatagaaatc ttgaaactag
    63361 aaaaatagca aaagatgatt taaaaaatag ttttgatgaa attaataaag aattaaaaac
    63421 tatagataga cagcatatag aacttaaaga aagtttattt aaagttggtg gaagattaga
    63481 aagattaaaa actagtcaag acacatatat aaataagttg tttgagcaat atgatatgac
    63541 cttagtacaa gcattggaaa ttaaagatga agatttggat atagatagaa aattcttaga
    63601 aagtctaaag agagaaataa gaagtcttgg aaatataaat atagactcta taaaggaata
    63661 tgaggaaata aaagaaagat acgattttta tagcgaacaa aagcaagatt tagaagagtc
    63721 tatggaagag atagaaaaac ttatacatac tttagaagaa aatatgaaat ctgaatttga
    63781 aattaagttt gaagaaataa gtaaaaattt taaatatgta tataagagat tatttggtgg
    63841 aggttgtgga gaattaacta ttttagataa agaaaattta ttagaaagtg atatactaat
    63901 aacagctcaa cccccaggta aaaaaatgaa aaatttaaac ctattatctg gtggagagaa
    63961 agctttaacg gcaataagta tattatttgc tatattgatt acaaagccaa caccattttg
    64021 tatattagat gagattgaag cgccacttga tgacgcaaat atatttagat ttggagaatt
    64081 tttgaaggat ttatctaaag agactcaatt tatatcagta actcatagga gaggaactat
    64141 ggaagctgct gattatatct acggagttac aatgcaagaa aaagccattt caaaagttat
    64201 tagtttaaaa ttaaaagaag ctcaggaaat aacagatatt atataactta gattgacata
    64261 ggaggaataa cagtgttaaa aaaattattt ggttttggaa aagacaagga aaaggaaata
    64321 gaaaaaaaag atgctgaaga agaaatagaa gttgaagaca gtgttgataa tttagaaaac
    64381 ttggaagaaa ctattttttc aggatttgaa gaagaagtga tagataaagt ggaagatgtt
    64441 gaagaaaaaa atgaggaaag tgtcaataat gaaggcactg aagaaatcga aaactttgaa
    64501 aaaatagaag ttgagatgga tagtaatgga aaagaggtag aaaatatttc aaataatgat
    64561 tctcaagaag agatagtcga agaattagaa aattatgatg aaattgagtc taaagagata
    64621 gaagataaag aagataagaa agttaacttg tttgaaagac taaaacaagg attgacaaaa
    64681 gcaaagcaag gaataactga tagaatagat gaagttttaa aatcatatac aaagatagat
    64741 gaagaattac ttgaagattt agaggaaatt ttaataacag cagatgttgg tgtaaataca
    64801 actatggata taattgaaag actaagagat aaaataaagc aaaaaggtat tactgaacca
    64861 ataaaggtaa gagaagaact taaatctata gttgaagata ttcttacaaa tgaaaactct
    64921 acactagata tagaaccagc accatgtata atattaatgg tgggtgtaaa tggggtcggt
    64981 aagactacta caataggtaa actagcaaat agatacaaaa aagatggtaa aaaagtttta
    65041 ttagcagcag cagatacatt tagagcagca gcaacagagc aattagaaat ttgggcaaat
    65101 agaaccaatg tagacataat aaaacatcaa gagggagcag accctggagc tgtagtattt
    65161 gatgctataa aagctgcaaa agctagaaaa acagatgtat taatatgtga tacagcagga
    65221 agattacaca ataaggctaa tcttatgaat gaacttggaa aagtatttaa aatagtagat
    65281 agagaatttc cagaagcaaa acgtgaagta cttcttgtgg tggatgctac aacaggtcaa
    65341 aatgcagttg ttcaagcaaa gacatttaaa gaagttgcag atataacagg tatagtactt
    65401 acaaaacttg atggaactgc aaaaggtgga gtagtccttg cagtaaaatc agaagtagat
    65461 gtacctgtaa aacttattgg agttggagaa agtgtagaag acctacaaga tttcaatgca
    65521 aaatcatttt cagatgcatt atttggtaac taatgttctt ttaaaaataa tggttgacaa
    65581 gagtgttgtt atgatataaa atacaatagt gtaaagtaaa taacctttac agtatactgc
    65641 taggaagtgt aagatatgaa tatagaaaaa atggtcgaaa ttggattgtt atttgaacag
    65701 tataaagaat tattaactga caagcagaaa gaaatagttg ctctatacta tgaagaagat
    65761 tattctttag gtgaaattag tgaaaatctg aatgtatcaa gacaaggtgt ttatgatacc
    65821 ttaaagcgtt cagaaaaaat actaagagat tatgaagaaa agttacactt agtatcaaag
    65881 attcaagagc aggaaaaaaa tattaagatt ataaaagata aaattattga cattaaagaa
    65941 gatttattgc acaataaaga ttgtgctaat ttaatcccta agctagaaaa tatagaagat
    66001 gtatgtaggg agatgataaa atgatatttg aaggattgtc tgataaacta caaggggcat
    66061 ttagtaagtt aaaatctaaa ggaaaactta cagaagtaga tgtaaaaaat gctatgagag
    66121 aagttaaact tgctcttctt gaggcagatg ttaactttaa agtagttaaa gatttcataa
    66181 aaaaagttca agagagatgt gttgggcaag aagttatgca aagcttaact ccagctcagc
    66241 atgtaatcaa aattgtaaat gaagagctta caagtttaat gggagatgta caaagtaaag
    66301 taatgatttc ctcaaagcct cctacaattt taatgatggt tggattgcaa ggtgcaggta
    66361 agactactac agcaggaaaa cttggaggat attttaaaaa gcaaggtaaa aaacctctat
    66421 tagtagcttg tgatatttat agaccggcag ctataaagca acttcaagtt gttggagaaa
    66481 aattggatat acctgtattc aatatgggag ataaagaaaa tccagtaaat attgcgaaag
    66541 caggtttaag tcatgcgatt aaaaatgcta atgatttagt tattatagat acagctggta
    66601 gacttcatat agatgaagta cttatggatg agttaaagtc tattaaatca gaagttaagc
    66661 cacatgagat acttttggtt gtagattcta tgacaggtca agatgctgta aatgttgcag
    66721 aaagcttcaa tgaggcactt ggtgttgatg gagtagtatt aactaaattg gatggagata
    66781 ctagaggtgg tgctgcactt tcaataagag cagttacaca aaagcctata aaatttatgg
    66841 ggatgggaga aaagctagat gatatagaac ctttccaccc agatagaatg gcatcaagaa
    66901 tattaggtat gggagatgtc ttaagtttaa tagaaaaagc acaagaaaat atagacttag
    66961 agaaagctaa agaattagag caaaaaatta aaaaacaaga gcttgatttt gaagatttct
    67021 tacaacaaat ggaacaaata caaaatatgg gacctcttga caagatactt ggtatgatac
    67081 ctggtatggg aaatgtaaaa gaccaacttg gagatgtaga tttgaatggc aaagaaatga
    67141 agagaacaaa agccataatt cagtcaatga ctacatatga gagaagaaac ccaggagtat
    67201 taaatgcttc aagaaagaaa agaatagcta aaggcagtgg aactagtgta caagatgtaa
    67261 atagacttat aaaacaactt aatgaaatga aaaaaatgat gaagatgttt gctggttcac
    67321 aaaagagtat gaagaaaagg ggcggcttag gcggtttacc tttttttaaa taaaatataa
    67381 aaaagtaaaa attattcgga ggtgactgta atggcagtta aaataagatt aaaaagaatg
    67441 ggagctaaca aaaaaccttt ctacagaata gtagtagctg attcaagagc tccaagagat
    67501 ggaaaattta tagaagaaat aggatactat aatccaattt ctgaacctaa acaagtaaga
    67561 ataaatgatg aaaaagctat aaaatggtta gctactggtg ctcagccaac agaagtagtt
    67621 aaaaaattac ttgtaaaaaa cggagtaata gaaaaattcg aagcttctaa acaagcaaaa
    67681 taattttttc ttggcaatta gtttaagtaa gggctcattg ctaaggttac tttaggagat
    67741 gaaatatatg aaagagctag ttgtagatat agctaaggct ctagttgata atcctgactc
    67801 agttgttgtt gaggaatttg aagataatga tggtatcgtc ttaaagctta cagttgctca
    67861 agaggatatg ggtaaggtta ttgggaagca gggaagaata gctaaagcta taagaactgt
    67921 cgtaagatct gttgcaaata gagaaaatat aaaagtttct cttgagatag tataaaatag
    67981 gaggattagg tataatgcct agtccttttt atataaatgc gtagtttaag attttatgat
    68041 gatatgacca cataagatta aattttttaa gaaggtgata acatgaaaga aaaattaact
    68101 cattttaagg taggtcaaat agtaaataca caaggtttaa aaggtgaagt aagagtttat
    68161 ccgcttactg atgatataga gaggtttgat gaattaaaag atttctatct gggaaaagat
    68221 ttaaataata aattggctgt tgaaaaagta agatacaaag gttctatggt tataatgaag
    68281 ataaaaggca tagacagcat agagaaagca gaaaaactaa aaaataaatt tatgtatgta
    68341 gctagagaag atagcagaga gcttgaagaa ggcgaatttt ttatagcaga tatgattgga
    68401 atggaagttt taactgtaga tggaaaatat gtagggatac tagaagatgt tcttcaatac
    68461 tcagcaaatg atgtctatgt agtaaaaggt gaggaagata aagaatttat gataccagct
    68521 ataaaaaaat ttgtacctac aatagatatt gatgaaagaa aaatgattat agaccctatt
    68581 aagggaatga tagattaggt ggtaatatga gatttcatat aatgacactt tttccagaaa
    68641 tatttaattc gtacatggat gaaagtataa tgaagagagc agttgaaaaa ggtataattg
    68701 aggttcatat atataatata agagattttt ctaataataa acataaaaaa gtagatgatt
    68761 atccatttgg aggaggagcg gggatggtaa tgactcctca acctatatat gacacatata
    68821 agcatataat aacaactcat aatataaata acccaagtgt aatttatctt actccaaaag
    68881 gtaaggtata caatcaatct atggcaaagc agatgtcttt aaaagaagat ataatactac
    68941 tatgtggtca ttatgaagga atagatgaga gaatcattga tttaatagtt actgatgaaa
    69001 tttcaattgg agattatgta ttaactgggg gagagctccc agcacttata atgatagatt
    69061 ctatatcgag attaatacca ggtgtattaa accaagaaga atcatttgaa gaagaatcat
    69121 ttaaagataa cttattggaa tatcctcatt acactagacc tagagatttt gaaggattaa
    69181 aagtaccaga agtgctttta tcagggaatc ataagaagat agatgagtgg agaagagaag
    69241 aatctataag gataaccaaa gaaagacgat ttgatttata taaaaaatct aatgaaaaat
    69301 aaaaatctaa tgaaaaatta atatatatgt atacaataaa gtacctataa atggaattaa
    69361 aaacataaaa gtgcttgtaa taactattga agtatagtat aatataaaat gttgaaaata
    69421 cgggcgttcc tctgtttaca ctggtcgggt agttaagaac gtctatgata tctaggagga
    69481 agaaagatga atgaaatgct aagagcaatt gagcaagaac aattaaaaaa tgaagttcct
    69541 aattttggac ctggggacac agttaaagta cacgttagaa ttatagaagg aaaaagagaa
    69601 agaatacaag tattcgaagg tgtagtatta aagagacaag gtggaggagc aagagaaact
    69661 ttcacagtta gaaaaatgtc tttcaatgtt ggtgtagaaa gaactttccc agttcactct
    69721 ccaaaaatag aaaaaataga agttactaga aaaggtaaag taagaagagc taaactaaac
    69781 tacttaagag gtagagtagg taaagctgct aagataaaag aagctagaaa taaataatta
    69841 aaaactttac ttataaatgg ggggctgatt tatcagtcct ctttctattt taatgaaaat
    69901 tacagcaaat aattatacta gaaataaata gaaatatttg ttgaaaatat acattattta
    69961 tctatgaatt tatagctttt aaaatgaaaa ataaaattgg taaatattgc attatatttt
    70021 gtaacaatat taaaaataag agaacagtat tatgtaaagt atgacgttaa aaagatgaca
    70081 atattatagc ttgttaagat agatttttta agtggaatta ggatataata atataatatt
    70141 aataaggagt gatacatgtg tcaaatgaat acgaagagta tcttatgaat gacaatctac
    70201 atataaactg gtatccaggt catatgaaaa aaactaagga gttagtaaaa aataacttaa
    70261 aattgattga tgtagtaatt gaacttttgg atgctagaat cccgtttagt agtaaaaatc
    70321 cagacataga caggcttgta ggagataagc caagagttgt cgtacttaat aagagtgata
    70381 tggcagatag ggataaattg aatcaatgga ttgaatacta taagaaaatt aatatcaaag
    70441 ctataccagt agatacaata aaaggcgttg gtataaataa gataatcgaa gaatgtaaaa
    70501 atgtaactag agaaaaaatg agttctttaa aagacaaagg gagaaaagaa agagctatac
    70561 gaataatgat agttggagtt ccaaacgttg gtaaatcgtc tcttataaac aaattaacag
    70621 gtagaaaaag cactcaaact ggagataagc caggagtaac gaaagggaaa caatgggtta
    70681 gattaaaggg aaatcttgaa cttttagata cacctggaat actttggcct aagtttgaag
    70741 accaagaagt tgcattaaat ttagcattta gtagagctat aaaggatgag attttagata
    70801 ctgaaacttt ggctttaaga cttatagaga aacttatgaa aatagaacct gagaagttga
    70861 aagccagata taagttagat tgtctaggag aaactccaat tgaaactatg gatatgattg
    70921 gccataaaag agggtttata acaggtaaaa aagaactaga ttatacacgc atagccacaa
    70981 ctgtattaaa tgaatttaga gatggaaaaa taggaaatat aacattggaa gttccagaaa
    71041 acgttaaaag atagatttta aaacaaaatc aaaaatttaa tgttaaaaat ttaaaaaagc
    71101 cttttagcaa aggctttttt atttttttga aatatagaca aatatctcca tataaaagta
    71161 taaattaggt tagaaaacct ttaaaaatat taatttaaga caaatatacc taatattttg
    71221 aaaattaaaa tgagtgtgat tatttaaaat tttagcatat tgacttgctt gtttcgtata
    71281 atatataata agcacaaata aatacaatat attaaaaatt taatttattt aattttatta
    71341 atttaataat aagttcttat tgtttaattc aacttactta tgcaagcgta aacaatcgag
    71401 acattttatt aatttaataa ggttaaaaag ggggatttta taatgggtaa gaccaaggat
    71461 gttatagtat ttggatttgc gttatttgca atgttctttg gagcaggtaa cttaatattt
    71521 ccaccttact tgggaataat tacaggtcca gaatggttaa ttgccttctt aggatttacg
    71581 tttgctgatg ctggattggc acttctagca gtaatggcta cagctaaatt cgatggaaac
    71641 gtagttgaaa tgtttaaaag atgtggtatg aagttaggaa ttcttatagg ttgtgcagat
    71701 attttatgta taggaccatt cttagctata ccaagaacag gtgcaacaac ttatgaaatg
    71761 ggtataatgc ctttgtttgg aacttcaatt ccagtgttat tattctgtat actttttttt
    71821 gcgatttcat atgtactaac aataagacct tctaaggtcg tagatatagt tggacagttt
    71881 ttaactccag ctcttctaat agctttagca tttataatta taaaaggtat tatatcacct
    71941 cttggagata tagtagataa acctatgata cctaatgtat ttgcagaagg tataggtcaa
    72001 ggatatcaga caatggatgc ttttgcagca atagcacttg catcagtgct aatagtatct
    72061 ttaaatgata aaggatattc tactattagt gacaagttga aaatgattgg taaggcgggt
    72121 gttcttgctt gtggaggatt agctctagtt tatggaggat tatgtttcct tggggcaact
    72181 gtatcaacaa tgtatggaac agatgcagta caatcacaag taatagtaaa tataactgaa
    72241 ggattgcttg gaaatgttgg gaaagcgatt ttagcagtag tagtatcatt agcatgttta
    72301 actacatcta taggtcttac atctgccaca ggtcaatatt tctctagact tacaaaaggt
    72361 aaattgagtt atgaaaaaat agtattagct gtatctgtat tcagtgcagt agtagcatct
    72421 tttggtgttg gaactataat aaagatagca tctcctatac taagtatagt ttatccacca
    72481 tcaattgttt taataatttt agctttcttc aatgaaaaaa ttaagaatga taatgtatac
    72541 aaaggagcag tatatatgtc attgcttgta agtatactaa cagttatatc tagttatgga
    72601 gtagctgttc cagtagtaaa ttctttacct cttaattcat taggatttaa ctgggtggtg
    72661 ccagttataa tagctggaat aattggtaat tttataccat caaagagtca atctaataca
    72721 cttggaacaa actaagtttt gtttaattaa aatataatca attgtaaata aatgagttaa
    72781 ctaaaagtaa aaggagttat ttgtacaaat aactcctttt atttttagat tctatattta
    72841 att
//
LOCUS       DAMJXI010000014        71553 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.014, whole genome shotgun sequence.
ACCESSION   DAMJXI010000014 DAMJXI010000000
VERSION     DAMJXI010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 71553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71553
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.014"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            194..910
                     /locus_tag="PC465_001237"
     CDS             194..910
                     /locus_tag="PC465_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2648560.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMKLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVSIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAVNTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
     gene            885..3218
                     /locus_tag="PC465_001238"
     CDS             885..3218
                     /locus_tag="PC465_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2648561.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQASAKGGA
                     ENPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVLD
                     TTKNDASKENSDENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSYG
                     VNQKVINQMLLSKAREDLMDTSLGGNSISYKLSPIKNITLVYAVPKAISKGDSVEYGY
                     GNTYFDDGIISYISNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTLS
                     RIPLEILFIALAIIQGLVDLYPTVIISNTLSGNYVEYLINNDISAKMASILVSLMNLT
                     YWFVIFSIIFVFIILLKHILNVGIREYFTKHTMTGMFFVWLKKAGKTVINQIRTINLK
                     EKPNKTIVTILGINLLIIVIMCSMWFFGIILALIYSVVLFKILSDYSKKTIYEYNQLL
                     DVTKKISDGNLDVNMEKDLGFFNPIKDELGNIQTGFKKAVDEEVKSQKMKTELISNVS
                     HDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKANSGD
                     VYLNIVNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENLI
                     INISKYAMPNSRVYIDILETDNKVNIMLKNMSASEIDFSVDDIMERFVRGDKSRNTEG
                     SGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
     gene            complement(3535..6213)
                     /gene="mngB"
                     /locus_tag="PC465_001239"
     CDS             complement(3535..6213)
                     /gene="mngB"
                     /locus_tag="PC465_001239"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HDF2648562.1"
                     /translation="MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKE
                     DFKYFTMDAQASLLDDYLKWRPQDEYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIR
                     NLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE
                     FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNG
                     FDQAPIRKNLPDILKKANEIDNENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHM
                     RIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPHLVIKDIWKLMFENA
                     AHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGF
                     PEVRNEVVEFDTYIPGQDFVIKNKNGEILNYIIKEKEDITNYILTQTIRLNPSKKIYI
                     PKTVYRAKIALSVKDIPPMGYTQLVFELDTKNKCEIETSNCKEIENKYYKITANKNGS
                     LEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLKSNIQEE
                     MILKYSLTIPASLEERAIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRV
                     LFNTEIASKFSIADQQFGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLED
                     GQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGRENLLYRPGRASGEKIIATPD
                     AQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLIFAFNDEKQ
                     IYENEYSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYS
                     AMLDEIYDNTSKLKVNTKTVEVNSLSHCKVQTIVIK"
     gene            complement(6288..7394)
                     /locus_tag="PC465_001240"
     CDS             complement(6288..7394)
                     /locus_tag="PC465_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDF2648563.1"
                     /translation="MSKKNKSLLSELKGHLMTGISYMLPLVIGSSLVVAIPKLTALAV
                     GITSLDAYKNVSGFYHILYLMEQVGWTGIGLLNTVLAGFIAFSIGEKPAMGAGFIGGL
                     IASNTNAGFLGAVIAGFFAGYVCKFLKKKIKISGSASGMMPLIIMPLITVGLTGFLMS
                     VVLAGPLGNINTSLNAWVAEMCQNGTNSVVLALILGAMIGFDLGGPVNKAAWMAGNAL
                     LLEGIYLPAILVNCAIVIPPLGYGLATFIRKSKFSNALAETGKGNIVMGIIGITEGAI
                     PFTLTNPLKLVPVNMIGCALGVGLSALLGVHAIMPPVGGLYGFISIGSGWAYLVGAIF
                     GALVIAILSTTLVDFNEDETTENIEFDEIELDIM"
     gene            complement(7508..7816)
                     /locus_tag="PC465_001241"
     CDS             complement(7508..7816)
                     /locus_tag="PC465_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDF2648564.1"
                     /translation="MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGR
                     VNTITKEEAQDADFILIASDQTISGMERFDGKKVIKVKIGIALKKPEAVLTKCIEAIS
                     "
     gene            complement(7819..8271)
                     /locus_tag="PC465_001242"
     CDS             complement(7819..8271)
                     /locus_tag="PC465_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2648565.1"
                     /translation="MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTNKEALLKDL
                     LKRENEFPTGIKDGFAIPHTKSVNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAP
                     HKNEGNIHLKTLSKLATCLMEDDFTSEVKNASDASHLVKYITNKMKEE"
     gene            8505..10433
                     /locus_tag="PC465_001243"
     CDS             8505..10433
                     /locus_tag="PC465_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2648566.1"
                     /translation="MHKRLLTLFKLLNESDDKITCKTLSNHLKVSERTIRNDITSING
                     TLEKNGAIIKIKKGEGYYIDILNLALYQQYLALISDDIMDSSEIPDSPIERNQYILKY
                     ILYNNTYIKLEDLANSLYVSKFTILNDIKRIKPILSKYNLILVSKPYYGVKVEGKEID
                     IRRCISNNMINRNFENYIIGITDREIELFNNVDLIELQRVVLSEINKFNINFLDFNLK
                     NFIIHLAITVSRILDGYCLDNVLDVVLTDFQSNTTVENIFNYIESKYTIIISKADRVY
                     LYNHFITKSSLLDNVSNRVDTKIIEYVEEILEVINNQYTFDLRNDSVLFDDLVLHFKS
                     ILNSKSYNLNKVNPLINTIKSNYPLAFEITLNAIEKVFKNSIYSLTEDEIGYVSLHIG
                     AGIERFFQSNIKCKNVVLVCGSGYGSSRLLEVQLNKVFHDKINILQCLSFNQFLASEL
                     SDVDIIISTIPLNHDSIPIVLVDLKLLKKDIENISKSITNNSHIYSNLLDNFFDKNLF
                     IVNPKIKDKDELIKLMCNKLTQSEIVFPSFAESVFYRESLSSTNIDDFLAIPHPMELS
                     SIRTKICISILDEPIYWSEDSTVKLIMMLAINKDDYIKINSIYDILLKIIHDNDIRDS
                     ISNCNDFDNFLSIIKSIV"
     gene            complement(10693..11454)
                     /locus_tag="PC465_001244"
     CDS             complement(10693..11454)
                     /locus_tag="PC465_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2648567.1"
                     /translation="MEYTVQKLSKLAGISTRTLRYYDEIGLLKPLKINSSGYRIYGQN
                     EVNKLQQILFYRELGINLENIKNIINSPNFDSLSALKEHHNKLLAKRKQIDLLIENVT
                     KTIALKEGKYTMTDIEKFEGFKEKMIDENEKNYGTEIREKYGKDIIDTSNKKLKNMSK
                     QDYENWQNLNIEIISKLKKAFKTGDASSELAQEVAKLHHKWLSYTWNTYSKEAHSSLA
                     QMYVYDERFTSYYDREQPGLAKFLRDAIVIYTRDK"
     gene            11673..12149
                     /locus_tag="PC465_001245"
     CDS             11673..12149
                     /locus_tag="PC465_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDF2648568.1"
                     /translation="MNLKRSNEKREEYRRMYSDKESFLSLIQNFTSVSIAKELTLKNI
                     ELETSFICEYKGKEVDIIYKVFSKSGKVSHYIVLEFQTEMDTEIVPRLKSYREQIWKS
                     FIMKKSLEEIEDKNFKLPKVIPVVLYSGPERLSRKKGILDIVESISEFSNNSSMKN"
     gene            12247..12399
                     /locus_tag="PC465_001246"
     CDS             12247..12399
                     /locus_tag="PC465_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate translocator"
                     /protein_id="HDF2648569.1"
                     /translation="MRNNKSKVLLGILCLATGMAVILSMLLPGWIWSALTALILIGCG
                     ALLFFC"
     gene            complement(12559..12747)
                     /locus_tag="PC465_001247"
     CDS             complement(12559..12747)
                     /locus_tag="PC465_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HDF2648570.1"
                     /translation="MAKVCSVCGKGKVSGNQVSHSNKHNKRTWSANLRSVRAIIDGAP
                     KRVKVCTRCLRSGKIERA"
     gene            13108..13458
                     /locus_tag="PC465_001248"
     CDS             13108..13458
                     /locus_tag="PC465_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDF2648571.1"
                     /translation="MSAKVTNQYGNIEIDNQVIAQVVYRAAMESYGLVGLAYKSKGIV
                     ELLKGENATKGVRVEEVEEDAIAIELYVIIQYGTNISTVANNIIDRVKYVVEKMTGVR
                     VTRIDINVQGIRVK"
     gene            13477..15120
                     /locus_tag="PC465_001249"
     CDS             13477..15120
                     /locus_tag="PC465_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HDF2648572.1"
                     /translation="MIQYIDGKRLREMFISGANNLQNNKELVDKLNVFPVPDGDTGTN
                     MSLTISYALKELAKVENDNISDIGKALSKGSLMGARGNSGVILSQIIRGIAKSIEGKS
                     KLSTEDLAKAFKNGSDTAYKAVIKPIEGTILTVVRESGEFAIKTAKKEKDVVKFLSML
                     VKESNSSLERTPDLLKNLKEAGVVDSGGKGLVLIYEGMLASIKGDNIEIKNVDLDTNI
                     STSMDFTKSTTSTDDIKYCYCTEFILESSKVEDTKIRDIMMAYGDSLAVVGDDGVIKV
                     HVHTNDPGNVLQEALKYGQLLTIKIENMKLQHENTLLDVEEKKENDSEPLEEEKEFGF
                     IATSMGEGLANIFKDFGVDHIIEGGQTMNPSTEDFMNAIKHINAKNIFIFPNNSNIIM
                     AANQAKELSDKNIIVIPTKNTPQGFAALVTFNGELSEDENKEAMMNALNSVKSGQVTF
                     AVRDTVMNEIDVKEGNIIGIAEGNLLSAGDYVDEVTSNLIEKLVDEDTAIITLFFGED
                     VTESQANELRTSLEEKFEDVDVELYYGGQPLYYYLISVE"
     gene            15201..17258
                     /gene="recG"
                     /locus_tag="PC465_001250"
     CDS             15201..17258
                     /gene="recG"
                     /locus_tag="PC465_001250"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HDF2648573.1"
                     /translation="MDLYKDVQYVKGIGPKKADKLNKLGIFTLKDLLYYFPRQFEDRN
                     NLKKIAQLEDGEKVTIKAVISSINTFSPKEGMTLTKIDVKDETGSAKLVFFNKSYIKN
                     TFRPGDSILVFGKVKKKFNNLELTSCELEYLTNSPKNTCRFMPVYQLTYGVTNKEIMS
                     IIRTVLEDKELIIQEYMPQRIIEKYRLCSIDFAVRNIHSPSSKESLKIALYRIVFEEL
                     LILQLGLFVFKSGRNKEDGIKFETSKDLKKIISALPFKLTKAQNRALDEIIQDMNLEK
                     IMNRLVQGDVGSGKTVVALLALANCVLNGYQGALMAPTEILAGQHYISLTESLKDFGI
                     NVGLLIGSLTKKQKDTVLEQIKNNEIDILIGTHALIEDKVEFNNIGLVITDEQHRFGV
                     MQRSKLSLKGANPDILVMTATPIPRTLALILYGDLDISIIDELPPGRQPIETIAIEKS
                     KRDRAYNNLVRREVESGRQVYIVCPLVEESEAIEAKSAVELVEELRAEYFHDLRLGLL
                     HGKMKSSEKDEVMRLFKNKEIDILVSTTVIEVGVNVPNATLMIIENAERFGLAQLHQL
                     RGRVGRGSHKSYCVLIYDSKTDVCRQRMAIMEETNDGFKISEKDLEIRGPGEFFGTRQ
                     HGLPELKVANLFKHIKILKLAQQEARYILGEDNNLQLKENMALKKEIIDKFKDTLKEI
                     SLN"
     gene            17317..17871
                     /gene="rsmD"
                     /locus_tag="PC465_001251"
     CDS             17317..17871
                     /gene="rsmD"
                     /locus_tag="PC465_001251"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HDF2648574.1"
                     /translation="MRVISGKARGLKLNTPKNEDVRPTTDRVKESLFNMINSYIMESE
                     VLDLFAGTGSLGIECLSRGAKSCTFVDISKESIDIVKSNIKKARVESESIILNLDFKT
                     AIDKLKLQNSKFDIIFMDPPYYKNMFIEAIEKIDNSNLLNEDGIIVVEHDTNDLFPDK
                     ICKLEKTRDKKYGNTTLTFYKMEA"
     gene            17873..18370
                     /gene="coaD"
                     /locus_tag="PC465_001252"
     CDS             17873..18370
                     /gene="coaD"
                     /locus_tag="PC465_001252"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HDF2648575.1"
                     /translation="MENKPRKAIFAGSFDPITNGHLDIICRASKLFDELQIGVLNNPN
                     KKGLFSFDERVKLIEKSTSHLNNIKVVTFDGLLINYCQENGIGALVRGVRSGADVDYE
                     LQMAHMNRELNPDIETIILPSCTKYSFISSSLIKEVLLFDADIKNLVPKIVLEELKKK
                     TSGGN"
     gene            18374..18898
                     /locus_tag="PC465_001253"
     CDS             18374..18898
                     /locus_tag="PC465_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648576.1"
                     /translation="MKIDLEMIELFEQLEEIFRSASTIPFSHKCTVDKDEVLAIINDI
                     RTLIPEEVTQAVWINKERNKIISQAKQDATNIVEQAKKEAERIQQEYQDNIEELKKNS
                     EDVVKAYVESSEPVVQADQRAKDIVDRAERIANEIRIGSIEYAEDVLSSVEYNLREIL
                     EEVKRDKAELRPKK"
     gene            19242..21161
                     /locus_tag="PC465_001254"
     CDS             19242..21161
                     /locus_tag="PC465_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2648577.1"
                     /translation="MKERAKKILDFIIKNNNVTSQELQEKFNVSKRTIYYDILAINKQ
                     LGKSGNIKNVKHKFIFEGNLCDARKIISTEEDKFLDSDYRKTFILNKILLGEKISIEK
                     LTNEMLLSKNTVVQTITDVKKYLQTMGLRLEYKGKYKIIGDEYVIRELFLIIVQENVL
                     EINSISEEVSSFDTKGHIKLTDYSLLNLTKFVEFLNKRIRDGKTLYSYKYLNEAKKIS
                     YFSNCKELLCEEANENEQAYICTYISSLPSLNSEVKEDVVEEYVDKLIDKFEVNTAIK
                     LESKHEFKKNILRHLHSSYNRIRFKFPIRNPMLDETKYKHESLYKIIKSIIENEEEFP
                     VFEGIREEEIGFIAAYFGGYLRGSRDNGLRRNKVLLVCPNGLMVSKSLEIQLYKYIPT
                     IEIVGIVSIKQLKEVNVYYDYIITTIDIQNVNNVIVVNPLLTSSDVQLLMNKLISVKE
                     NEKYFNLELIIQAIRKNGVINNEEALKADLLNIIHKIDEGEMYQPMLKELINAERVNI
                     IKNVRDWKEAIKIASKPLLEDNSIEELYIENMIKSVEKYGPYIVLADRFALPHASSKE
                     GVNKLAMSLLIVEDEVDLLGKPVNIFMVLAAVDNTTHIRALASLSEMMYEEENVKLII
                     NGDKSSILELINKQN"
     gene            21174..21461
                     /locus_tag="PC465_001255"
     CDS             21174..21461
                     /locus_tag="PC465_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2648578.1"
                     /translation="MKILAVCGFGVGSSMVLKMTIQKALKQLGIECEVENTDINSARG
                     ADCDCIFTSQELLNELKGTCNVDVYPVKKYMDLAEVTEVVQTFLSDKNDKK"
     gene            21594..22853
                     /locus_tag="PC465_001256"
     CDS             21594..22853
                     /locus_tag="PC465_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDF2648579.1"
                     /translation="MLDFISNNILRNPSMLIGLIAAFGLVLQKKKASDVIKGSLLAAF
                     GIIIMETGTGMLVSSIAPINGAFQSISGGAVTKGLSDVTFTASYGGIIGLAMFAGLAI
                     HLMIARFTPIKTIFLTGHMLYWFPFIFVASGVEAGLNGGVLIAFAAVLSALYWSIMPW
                     LLRKYVFDVIGDDSFTLGHPSGCLALISGFVAKLVGNKEKSTEDINIPQSLSFFREIS
                     ISGGMAVFLMFIVVGIVIPGAFKDSNEFIGTYAIKQGLSFGAGLIIMLHGVRMLINQI
                     MPAFQGISEKVVPNALPAFDCPILFNYKPNAVLIGFLVAMLTSTAMILICNYFNVFNL
                     LLIPLVITSFFECGAAAVIGESQGGIRGAIIGTAIAAIFMVVLVGISAVIYSGTIQNW
                     ILIFGGNDLSLFGIISRFIGSLFGGIL"
     gene            22856..23596
                     /locus_tag="PC465_001257"
     CDS             22856..23596
                     /locus_tag="PC465_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2648580.1"
                     /translation="MKFKYIDEIRRLIDIIENEEKVNMEKAVQILVEAIESKNAIFSF
                     GASHAGILTEELFYRAGGCVLINPVFAKSLMLDTAPITHTSKMERLEGYGTALADKTP
                     IKKGDVVIVHSVSGRNPVSIEFAMKAKENKAIVICITNLSYSKSVSSRHSSGKKLYEV
                     CDLVIDNHGQKGDACVEIDGLNQKVSPTSTVIATTVMNSIIAQATQELVNKGLKNPPI
                     FYSANIDGGDELNKKIFDEYKSVIHYEY"
     gene            23919..25229
                     /locus_tag="PC465_001258"
     CDS             23919..25229
                     /locus_tag="PC465_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDF2648581.1"
                     /translation="MKKENKMEGIKVGMLKKLCSLAMVAIMTTTLITGCSSGNGKDSK
                     KDGEKEKLVLWMPPVENNMKEVWDPILDKFEEKNNCEVDLQIIPWDNYSEKFATAISA
                     GEGPDVGYMYAEMYPQFIESGAVEDLTNYATKEDKEQSIYIKTSEMMGGMYGMPFQAA
                     NPGVLYYNKDILEKLGEKPPKTWEDFKRICKKATQDTDGDGKIDQWGLAQGWGAKTFG
                     NLNWNWYPYLWQAGGDIFNDDLKSVKFNDKSGLEAAKFLKELQAYVPEDSLSKDSNEM
                     IESVFGPGKAAFTIMLSSAATSVFDESFPDLNWGFVTGLEDKKAATFGAVDHLSLMSS
                     AKNKELAYKLIQHMLSVESMTEFHKAIPRAPITKGEPYQGDERFKEMVENDKNVYRPL
                     VVGPHGVEIYEYLWKELQTMISGDKTPKQALDDAAKYSNDLLAQ"
     gene            25327..26244
                     /locus_tag="PC465_001259"
     CDS             25327..26244
                     /locus_tag="PC465_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDF2648582.1"
                     /translation="MENLVREFEENSKRKKTKLNIKPYMYILPLGIILVAFYVIPIIM
                     SIYFSFTKYNIISPATFIGLENYKKLFTDETLKVSIINTIKFTVVVVPCQTILSLILA
                     VWITGKGNSKIASFAKGAIFIPVLSSMVLIGMVWRALLNGEGSIIYQVLGAFGIESSK
                     LLGDSKTALPTLMFISMWKNIGYFMVIYISAIMNLPKHCYEVAKVDGATKLQEFIKIT
                     VPLLKPTTIMVVFLGSIWSLQVFDLIYTVTGGGPGISTMSIVMHAFNLNFKNFNSGYA
                     MTVANVLFLLIAVVSILQNKLVRRDNSDF"
     gene            26260..27069
                     /locus_tag="PC465_001260"
     CDS             26260..27069
                     /locus_tag="PC465_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDF2648583.1"
                     /translation="MKTARRLLSDGLLLFIACASLVPFIYMLIISLKITYNSYSLDIS
                     FSTVTLQNYIDIFTKKGFAQYFFNTAIVSFSGVLLNLVFSTLAGYSFAKMDFKGSDKL
                     FLFMIMTLIIPSQVTMIPLYIIMKHLGWINSYLALIMPIPTAFGVFIMRQAILGVPKE
                     LLESAKIDGCSDFRILIQIVLPLIKPALITLAIFTFMGAWNEFMWPLIATTKDAMRTL
                     TVGLSTLKTFQITNYGQMMAGATITFLPPFIFYLILQSKFVEGVSLSGIKG"
     gene            27127..28875
                     /locus_tag="PC465_001261"
     CDS             27127..28875
                     /locus_tag="PC465_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
                     /protein_id="HDF2648584.1"
                     /translation="MEISYVLKDCTFKHNKYSVIEAETWKDKDLDIVVAKGEKFAFQI
                     MLKATEEFNCTIDKSSAISWKGLGNRVRLALNVPNSLENNFSINILGYVQDDTKAFVN
                     DAILRDKDVLVEQYLPQTFWIEGQVPEDFEENNLDIGIDIFKSFGYEDEEKVCTIDVP
                     VKVRNVVLKPLDESKFFLDLWQHPSCLARMYKVELWSDIHFEIVDNYLKELASLGEKV
                     ATVIVSDYPWAGQSCYKVYKNPSNLYEYNMVSVSKGLDGKIKCNFESMDRYIGIADKY
                     KMAKEIDLFGLLGNWCAGEFGNPVEGYKDPIRVRYFDEKDKVFKFINNTNDLKEYIGL
                     VLNHLIECGLWDRVRIIADEPNNPEVVKECIEFINSTVGTHQVKYKSATHDQNFLDRA
                     KDEIDDMSINLKLTIQNYKDIESLKKKINDKGGILTWFVCCFPEKPNSFLSSPFVENR
                     IIGWYTYYFGLDGFLRWDYNLWTEDPWKDSSYKFPIWKAGDMFFVYPGKDLKPVRSVR
                     MENLRFGIQDFELFTMLEKEKGREYIEVELMQELLNKKENAEIKGFGDIELGYSLDNW
                     GYDKVKKYVLELLDRV"
     gene            29137..30159
                     /locus_tag="PC465_001262"
     CDS             29137..30159
                     /locus_tag="PC465_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="HDF2648585.1"
                     /translation="MFGGINIKRIGIIIMFFLSISFIGFYLVIRDNSDTVKMQRGINI
                     GNALESPKDFPWDVKMSNKFFDDIKDAGFDTVRIPVRFSDYTSDSDNFKIDEEFFKKI
                     DKYVDYALDKDLIVVLDLHHFEEIMKEPRVHKEKFLKIWQQIANRYQKYDKKLVFELL
                     NEPKENLYSQLLNEYIEEAIKIIRKTNPKRTIIVGPYNFYQIDYLNELNIPKDSNIVV
                     SFHYYEPNDFAFQGNIYHKGFEHLSNITWEGTNEQMDYLKKRFDTVENWANKNKVKIF
                     LGEFGVTKEAPETSRRAWVKAVREEAEKRNFSWAYWELASGFGIYNQIEGTWDREILS
                     ALIEKR"
     gene            30164..32470
                     /locus_tag="PC465_001263"
     CDS             30164..32470
                     /locus_tag="PC465_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2648586.1"
                     /translation="MKKNSKKILITLTIITNIVYILWRIFYTVPKEEGMFALICAIIL
                     LFVEIMGMMEMFVHYYGMSNIEYPEKPIISEELYPHVDVFIATYNESVDLVRKTVNGC
                     IHMQYPDKKKVHIYICDDGNREEMCILAEKMGVNYITRTEREGAKAGNLNNAMQHTNS
                     PLIATFDADMIPMHDFLIATVPYFLKNEQAKKDGEKEEYEKVGFVQTPQSFYNPDLFQ
                     FNLHSEGRIPNEQDYFYRDIQLARNRTNSVIYGGSNTVISREALEEVDGFYTYSITED
                     FATGILIQSKGYRCYAIPEVHASGLSPTDLKSLIKQRERWARGCIQTGRRLNILFRRG
                     LGFWQKISYISSITYWYASIKRFVYIMAPILFSVFNVIVVKCTLLQVLVFWLPMYILS
                     SLSLKIFSQNIRNTRWTNIYETIMFQSLMPAVILETFAISKNKFSVTNKSKLEENRMY
                     KFLQGIPYFIYMVLSIIGILKMFVAIFKMSSMTYSVVLFWLIGNLFNLVMATLFISGR
                     QQLRKSERYIAEIDFKLKQNSYVLSSKTIDISENGFAFLLENPEYISPEEEFEVEFRE
                     KSGNEMYIANMKAKIVNVVEVNSKWKYAAYITHIEDSEIDNWMCIVHDRIPTLPMTIS
                     NQLGFFDDLQINVKKRIEKTRTLSRRSPRINMNFQMDIKNTGKLRIVNFNYQYVLLNF
                     ENKSIYPKEIALEINENIVLECDLCEGKIDERGILYKVNNIDSIMQNFFLRDEMMDWI
                     LQNKTILVSKPSEKKEKSIDEFEPMEYI"
     gene            32442..33557
                     /locus_tag="PC465_001264"
     CDS             32442..33557
                     /locus_tag="PC465_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648587.1"
                     /translation="MSLNPWNIFRRDEMKTLKVFFCSTKYLILVFIFFINTTFISSAT
                     SDKILDLSFKKIETDLSSKITYEDTGVRIETDSSKSDKERYLYIYQNIKENWSMYNNF
                     YIEIQNKNKSSQRINLSIQSKNMLEFRLKEGSEVFLEGKNIIYSDKIKEGCIEVPGEF
                     EGKIYVNFNSLINEESNVVLDSNMLSNIVSWGITFIPSDEEHNIVIIKKISLLSEEKL
                     RFLNNIKIIGDEEVQIPVLGQSISQYEVLGLKSDSKIKYSLMGKQDNVSISQKGKLTL
                     SNKAKPGQIILQVNVDDKFKIGKKITLTESWSVNKKDKDGVPYTLVYPEQSPTVQDMK
                     KINFMNNIITFVRILFVSLVIICFGIYLYWKKCSKTK"
     gene            33575..34993
                     /locus_tag="PC465_001265"
     CDS             33575..34993
                     /locus_tag="PC465_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HDF2648588.1"
                     /translation="MLFSSLIFLFYFLPITLVLYYVFRFNRTIQNMILLAVSLFFYAW
                     GEPKFVVIMIVSIIMNYIFGLLVDRYRESKIKVKVFLVLMCAYNIGVLFIFKYLAFAL
                     RNISELISTELTIPSIVLPIGISFFTFQGMSYVIDVYRRHGEVQKNPFYVGLYIAFFP
                     QLIAGPIVRYESVAEQILNRKETWNKFSIGTCRFITGLGKKVLISNNMAIVADYIYTM
                     NSQGEIAASLAWLGSIAYTLQIFFDFSAYSDMAIGLGLMFGFKFEENFNYPYISKSIS
                     EFWRRWHISLGMWFKSYIYFPLGGSRVANKDIMIRNMFIVWLFTGIWHGAEWTFVIWG
                     ILNFVFLIIERFIMFEKIENHNFIKHIYALLVVNFGWVLFRSPNLKEAYNYFKAMFGG
                     NGAIWSDYTYMFLKEYWVFFIFAFIFSVPIAKKINKFVVEQAKYSMIFNVFYPISAIL
                     LFFISVTYLVTGSYNPFIYFNF"
     gene            35008..36216
                     /locus_tag="PC465_001266"
     CDS             35008..36216
                     /locus_tag="PC465_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648589.1"
                     /translation="MNRFFKVRLITAIMFLIILFAFSIFNVCYSGKDTIQEIKNSIAE
                     KSSLKDTISSIDNTVNDKVIYKNTFIETYGYLQKLMGKNEFSKFSVVKDTSGKMHYTY
                     FAKAPNPVGVIADRVRKFSDEMEKQNTKLVYLMTPDKYIKGVTKFPKGIPYSYSNETA
                     DNFLNQLKKYNVDYIDFRENILKSGIPKDDLFFKTDHHWKVETSFWAFGELVEQLNKK
                     YNMNLDENHYYRDKDNYNSIVYPKSFLGSMGRKTGILYGGIDDFTLIYPKFKTNYTYY
                     TDSKSQKFELKGRFEESLILSYPFNADLNLMDGQSDKYFTYLLGNRPLVKIKNIENPD
                     GLKVLFVKDSLIVPTAAFFSSVCSSIDMIDPRYYDGDILEYAKSHDYDFVFISVYPQN
                     LTKEFFPFCE"
     gene            complement(36290..37678)
                     /locus_tag="PC465_001267"
     CDS             complement(36290..37678)
                     /locus_tag="PC465_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HDF2648590.1"
                     /translation="MESSFLSQFLMITDFKTIFFIILLLGTFFIVRQFEKKKIKFSLR
                     TIYATVLGLILGIIIQAFAGFPNDTTQVIWLQEVSKWYSLFGSGFMDLLKMLVVPLVF
                     LSIIKVIINMKDNNLGTLTFKSLGMLLATTAIAAIVGIIVANIMKLGVGANMPTLVEN
                     QELKEINSLVDTLRGLLPSNPVMAMANGNIVATIIFATFIATSIKRLSKKHFETIKPF
                     IDFIEASYKIIVSVSMTVIKFMPYAVVALLANTITSQGISSIVSVLQFILALYISVAI
                     LFIIHLIFITLNGLNPITYIKNSTEALLLAFTSRSSLGTLPVTIESLVQNHGVDEGVS
                     SFTASLGANMGMNGCAGIYPALMAVTLANMAGVNMDMSFYVMLLIVITISSFGIAGLP
                     GTATMAVSVVISGVGLGSYFPLVGGILAIDPILDMGRTMINVNGAMVSSITVGKSLGK
                     IDKEVFSKKNIS"
     gene            38019..39353
                     /locus_tag="PC465_001268"
     CDS             38019..39353
                     /locus_tag="PC465_001268"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HDF2648591.1"
                     /translation="MRVIIIGGVAAGMSAAAKLKRIKPEYEVVVYEKTEIVSFGACGL
                     PYFVGGFFNDADELLARTPEKLREAGIDLNIFREVVEVDSESKKIKVKNIKTDEIYED
                     YYDKLMIATGARSIMPSIKNIKLKNVSTLKSLYDGEYLKKLLSNEDNKRVTIIGAGFI
                     GLEAVEACKKLGKDVDVIQLEDRILPQVFDKEMTDVLEEEINRHNVNLHLDEMVVELC
                     GEDKVEKVITNKGEIDTDVVIIATGVRPNTEFLSNTNIKMLKNGAIVVDEYGRTSVED
                     IYSAGDCATIKNIVSNENVYVPLATGANKLGRIVGENLAGREVSYQGSLSSSCIKIMD
                     MEAASTGITERQAKDLGINVKSKFISDYNQTHYYPGRNKIYVKLIYDADTKVILGGQV
                     AGFKDAVQRANVLAAAIFGKMTTSQLGMLDLCYAPPFARTWDVLNVAGNISK"
     gene            complement(39495..40412)
                     /locus_tag="PC465_001269"
     CDS             complement(39495..40412)
                     /locus_tag="PC465_001269"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011969064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HDF2648592.1"
                     /translation="MIDLTLLGCGGNVPMPNRFLSSVFINYKGRKILIDCGEGTQVSM
                     KLKKCGFKDIDLICITHLHGDHIFGLLGLLSTIGNSGRTSDLTIVGPVGIVDCIRSMR
                     NLVEYVPYTLKIIENPQGNFSLDNKVLRNLEISTISLEHSIECLGYSFNFRRNPKFDI
                     DKATKNEVPKILWNKLQEGQNIVLDSKQYTPDMVLGELRKGVKISLTTDTRPIESIPD
                     FIKDSDLFICEAMYGDDLDISKAVRNKHMTFREAANLAKLGNVKQLLLTHFSPSLDIP
                     SMYLENATNVFENTILGEDRLSLRLNFDE"
     gene            40620..41504
                     /locus_tag="PC465_001270"
     CDS             40620..41504
                     /locus_tag="PC465_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4846 domain-containing protein"
                     /protein_id="HDF2648593.1"
                     /translation="MKVLKKITILLLITLTLVGCSNGEEKKVVEGSKKTQNSKKDEQP
                     IIVHKDANILKDRYEPPKGFKRVDVEKGSFESFLRNTKLKNYGEKVKYYDGRTKESKG
                     IYDSVFDVDIGNRDLHQCADAIMLMRAEYLYQNKLYDEISFDFVDGFKAKYSKWAQGY
                     RISVKDSGSSWYKATEYSTSYESFRKFMDIVFAYSGTLSLEKELEPVKVEDMKIGDVF
                     IVGGSPGHASIIMDMAENEKTGEKVFMIAQSYMPAQQTQLLINRKNPNLSPWYSLDFE
                     GDLTIPQWTFKRDQLKRF"
     gene            41717..43558
                     /locus_tag="PC465_001271"
     CDS             41717..43558
                     /locus_tag="PC465_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HDF2648594.1"
                     /translation="MKIRRYLILVIIILITTSQSFISYGLERFEEITIFHTNDIHGRY
                     AEGDDHIQIGNLATLKKETPNSILVDAGDCLHGLPIVNMDRGKSAIELIKCAGYDYIT
                     PGNHDFNYGKDRLFELSKSANLGENTLKFLSSNIFENGKKVFDSNDIKEIDGIKIGFF
                     GLSTQETKSKTGFKNVEGLEFKNPIESATEQVNELKGKGANVIVAICHIGTNSLSKPN
                     SIDIANEVQGIDLIIDGHSHTKFENGKQVGDTLIVSAGQYLENIGEIKLTLDTNDVEN
                     IKIENKSVRLIGKEEALKYKLDSAVSKKVDEIKEQQEKILDKVIGVTTNTLDGSYENV
                     RTKETNLGNLISDILLDKTKADISLFNGGNIRDTIEKGNITRRDIVDVFPFSNTIVTK
                     ELTGAQIKDVLEHGVKLYPEKSSAFLQVGGISYYFNPKQKEGEKITNIQKEGKPLDLN
                     KKYVVATNDYIASGGDEFPCFSKEPVLKEFGNLESAVIEYIEYKKEISKNVDGRIGIK
                     SKDELISKNHESDLILSENEKNINDNEENLSNNIKSSDSDKNKSLDKTSARESSNLGI
                     SKREAKEKSPKTGDLGFSNSIIIFIVSSTLICLLNFNQKELKDKKSK"
     gene            43863..44570
                     /locus_tag="PC465_001272"
     CDS             43863..44570
                     /locus_tag="PC465_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2648595.1"
                     /translation="MNNILLLEDDKSLNRGISFKLKKEGYNVFSAFGIEEAKNIFAKE
                     EICLIISDIGLPDGSGFDFCEEIRKKSDVYIIMLTALDEEVDIVTGYDLGADDYITKP
                     FSLMVLISKVNALMKRVNTVKNYTLLVCDDLFFYYIENKLIIRTDDKEEEIILSKTET
                     KLLKYLMENSMQTLTKEQLLESLWDSSGNFVDDNTIAVNIRRLRQKVEKNPSEPKYIK
                     TVRGVGYMWGERSIKKC"
     gene            44564..45874
                     /locus_tag="PC465_001273"
     CDS             44564..45874
                     /locus_tag="PC465_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2648596.1"
                     /translation="MLKNMNLKDGLSVKDDYIMRRVIVYSVLSVLIVTLVFILFEYSR
                     LHKLYEHQIKNTQNIAGILIEKYPNDEIDIVNSIYNSDYSKVSTGEKAFKKFGYGLEN
                     KMSNDKNFSLYLKSFFKESFFIFLMMFIVVIGIIYYFIRYINKRLSKIYFIVDKMSQE
                     NYLKDTTESEETGYLVEYNEYFKEGIFSKINNCLYELNRSLKIKFIKLEKEKESVKSL
                     VTDISHQLKTPLASLKLYNTLLIEEELEEDEANEFLLTNKASINKLENLINSLVNISR
                     LEISMINIKKEDNDIKNTILNAVKSVTPKAKSKSITLNLNEFNSRIIPHDKKWTEESI
                     FNVLDNAVKYTQVNGEINISVEETANFFKIIIEDNGIGIEKNEFNNIFKRFYRGSADE
                     IESVEGSGVGLYLSRKILEEQGGNIIVSSKVGIGSKFSLFLTTM"
     gene            45991..46674
                     /locus_tag="PC465_001274"
     CDS             45991..46674
                     /locus_tag="PC465_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2648597.1"
                     /translation="MKILYTENLSKHYGKGESLVRALDNVDLEINEGEFVAIIGKSGS
                     GKSTLLHMIGGLDIPTSGKVYIDNKNIFTLKEEELAVFRRRKIGFIFQSYNLIPSLNV
                     WENVVLPIGLDGREVDESFIKELLKSLGLENKHDVLPNTLSGGQQQRVAIARALATRP
                     AIILADEPTGNLDSKTSDEVMSILKSMSKKYSQTLVMITHDDSIAQMADRVIFIEDGR
                     VSKVGDKND"
     gene            46667..49054
                     /locus_tag="PC465_001275"
     CDS             46667..49054
                     /locus_tag="PC465_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2648598.1"
                     /translation="MINTTKIAKSNLKQNKSKSILIIITIILSTLMLSSIGIYIVDAG
                     AYQKENTIKYSGNYQGILANVDEKQADILSNHADVELTGEMNGVGVEKLEDDSNISLA
                     YMNEDALKLNSFEFIKGKLPSKENEIVLDSGALKALGYKNKDLGEKIKISYDDYKNDK
                     KIEKEFIISGILKTSEISEAGKYYYAIISESYMRNTRDMSQEDFNIYVKFNDKSNLSI
                     EQAKEKLDKIANDIGLDTINTAVNENYINALKPDMETIMGGVFVGLVIVLSSILVIYN
                     IFYISIVTKVQEFGKLRAIGATKKQIKNIVFKEGFILAGIAIPIGIILGYVLANIIIK
                     SFMDIDVKSSRLPVILSVVVISFISVVLSLLKPMKVASKVSIVDAVRYTGNKISNKSK
                     RKGYKNINLKRLSHANLERNKKRTYMTLASLILSGTIFITVSTALESFDAEKMAREHF
                     PYDIEVRLSGYEMNSDKNPKDNLNILQMDNPLSKDFFNQIKNMEGIKRIESARSVKIG
                     MEDYDVEFKYDLLQSINENDVKSLNKNIIDGKINLERLQTGDEIVITHVDTAKEMGVK
                     AGDKIRLTLYDGDKKIKKEFKVQAIAMGVPSFGIGKDFIDRTLKYDSTSSLGIYTEEG
                     KYQEIKDSIKKIAKNNGFLETDFIDSRIESNKATISFIKIMGYTLTGIIGVIGFMNLV
                     NTMITSIVTRKKELGMLQAIGLTNKQLVKMLNSEAMYYTSGMMIGSILFGGILGYIAV
                     IFLKKTGLSYATYSLPIVPILLMIVCILIAQFITTYLIGRSFNKESLIDRVRYSE"
     gene            49334..50476
                     /locus_tag="PC465_001276"
     CDS             49334..50476
                     /locus_tag="PC465_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HDF2648599.1"
                     /translation="MNKKINYAPGPTETRENVRLARAEKTTNPDIDIDFVEFYKKTCE
                     KFGNIIGTKNDVYILSGEGILGLEAACASLTEKGDRVLVIDNGIYGEGFKDFVTMYGG
                     EYVLFSSEYTKSIDIDELKAFLDEDSNFKYATVVHCDTPTGVLNDVSKICPLLKKYGI
                     LTVVDSVAGMVGERLSVDESKIDIILGGSQKAISAPAGLTIVGISQDAKNCIKNRKTD
                     VIGFYCNLNIWEGYYEKKYFPYTMPISDIMGLDKALDNILEEGIENVLNRHEKIAYSV
                     RKSIEEYGLELFLEEGYSNTVTAIKVPESIGALELTDYMLKNYNTLVATSLNQYMDTI
                     LRIGHMGENANLNKIEHVLNVLDKSLSALGFKGNGNLLNLFNKYYF"
     gene            50495..51019
                     /locus_tag="PC465_001277"
     CDS             50495..51019
                     /locus_tag="PC465_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2648600.1"
                     /translation="MEVTAKQKFTTKDMVETSLLIALVFIATKFINIRLPISINGGLV
                     HLGTAMLFISAIIFGGKKGALSGAIGMSLFDLISGWTLWAPFTFIVRGVMGYLLGKIA
                     WANGNNGNNFLINVIGICVSSIWMLFGYYVTEVILYGNFIVPLTSIPGNLMQVLIGLI
                     IALPISKVLKNCIK"
     gene            51119..51937
                     /locus_tag="PC465_001278"
     CDS             51119..51937
                     /locus_tag="PC465_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2648601.1"
                     /translation="MLSVTRYSIKNVRLKPWVKFIWYFETKSNILLNNKLLPTDSIDI
                     ILNLSDVMEYKIENQDYTASNMHFNGIRDKHGFIIQHGNIRVIGISFYPFGLYPFLKI
                     PISEFNRQIVDLEVVSQLFAKKLEESLSPTQSVEKIVLYLEEVLLSILEEDLISNKYV
                     KLLNSFIYVNRYSNIKAFCDDTNINIKTLERICLKYTGYTPKILKRIYRFKMASNQLI
                     YNYKDDELFDFIYENEYYDQAHFIKEFKKFSGTSPIKFIGENKTIKENIKYSYL"
     gene            52015..52326
                     /locus_tag="PC465_001279"
     CDS             52015..52326
                     /locus_tag="PC465_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HDF2648602.1"
                     /translation="MKIITEIVEFNVEENLSKEEFIEIVNDLELKFHSIQSGFIDTEL
                     LYDEKSQKWIMIQHWESIEDLKSASSKMFKDSSTEKFRKALKNQTVKMNIIPQIKSWK
                     L"
     gene            complement(52503..53186)
                     /locus_tag="PC465_001280"
     CDS             complement(52503..53186)
                     /locus_tag="PC465_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648603.1"
                     /translation="MQKEVAMNKLIKDCVNFFNDCGFSYSICGGYALELFANMHIRPH
                     SDIDIWISDTDKEKSIQYMLNQGWDIYEPLGNYLLRPIIDLNKQHIEQICVFAIKPDC
                     SFIELKKVEDDNYKMNIQCDEQLQFDFIELIHNPQKDGKFLFSQNQRIIRDMDKARLI
                     TSDNIPYMAPEVVLFCKSIYIDRLGYQKDFDVTVPLLSQEQRDWLVNALITAYPDGHA
                     WIDQLANQY"
     gene            complement(53279..53920)
                     /locus_tag="PC465_001281"
     CDS             complement(53279..53920)
                     /locus_tag="PC465_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2648604.1"
                     /translation="MGRKKEPDNTIQKILDISHKLFLEKGYEQTTIQDIVDNLDGLSR
                     GAIYHHFKSKDEIIKAITSRLYNDGFYGYEVKNDEGKTALEKLQYRLLHAYEQHNKQD
                     IFLMSSSLLRNPKYLATQFDEIINDIVPWIKALIEEGNQDNSMEVKNPEIAAQMFGFL
                     LNTWCIPTVYPGNPQQMIERFTLFGEQAAFMGISFMNDKIMCEYQKFVNKFSK"
     gene            complement(54094..56097)
                     /locus_tag="PC465_001282"
     CDS             complement(54094..56097)
                     /locus_tag="PC465_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase C-terminal domain-containing
                     protein"
                     /protein_id="HDF2648605.1"
                     /translation="MKSQKRFKILDIDVYLQPFESDIKKRMKHYEDMKSKTLKNYKDF
                     SSFANAHLYYGFHQTNDGFFYREWAPNADSLSLIGDFNNWNRKSHPLRKIGSGNWEIF
                     IPGQNSLPHKSEVKVQVTANGKTFDRIPLYIKRVIQKDFGGFNGQIWQPKTPFIWTDN
                     NFDLKNITSPLIYECHIGMSTESESIGTYNEFTEKILPKIKKAGYNTIQLMAIMEHPY
                     YASFGYQVSNFYAISSRFGTPEDLKNLINTAHSMGIAVLLDLVHSHAVKNTLEGINEF
                     DGSEHQFFHSGSKGNHPAWGTKLFNYGKPEVIHFLLSNIKFWLNEYHFDGFRFDGVTS
                     MLYHNHGLGVSFDSYEKYFSMNTDIEAITYLQFANELIKEIKPNSISIAEDMSGMPGM
                     CIPIKDGGIGFDYRLAMGVPDFWIKTISNLSDEDWDLGKMWYELTTRRPGEKNIGYCE
                     SHDQALVGDKTIIFWLADKEMYWNMEINSNNHVINRAISLIKLIKLITFSLAGEGYLN
                     FMGNEFGHPEWIDFPREGNNWSYKYARRQWSLSEDNNLKYKQLLNFDKSMLELTKYSD
                     IFIQNSHELIHMDNDKKILVYSKGKYLFIFNFHPNLIQSVDISKFQNTNYKTILNTDM
                     VEFGGNTKKENLRDYDVYFNSTPPSSKMPIASRTAIVLLDNGI"
     gene            complement(56250..56888)
                     /gene="recX"
                     /locus_tag="PC465_001283"
     CDS             complement(56250..56888)
                     /gene="recX"
                     /locus_tag="PC465_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HDF2648606.1"
                     /translation="MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGNE
                     INEEELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENIIERVIDFLKS
                     YNLVNDSVLAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTINEAVSELDKDTEFENA
                     MYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI"
     gene            57164..57853
                     /locus_tag="PC465_001284"
     CDS             57164..57853
                     /locus_tag="PC465_001284"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HDF2648607.1"
                     /translation="MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAH
                     LATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEI
                     ERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPG
                     ISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYL
                     YENKLYQYGDD"
     gene            57854..58426
                     /gene="yqeK"
                     /locus_tag="PC465_001285"
     CDS             57854..58426
                     /gene="yqeK"
                     /locus_tag="PC465_001285"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HDF2648608.1"
                     /translation="MNLENINQRLNQMLPVGRLSHSKNVAKCAEKLCEIYGCDKEKAY
                     LAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDED
                     IINAIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDTLRELAYGGKLDEALLTSFN
                     NTLMFVINKKEEIHPRTVMARNYLIKEKLL"
     gene            58543..58893
                     /gene="rsfS"
                     /locus_tag="PC465_001286"
     CDS             58543..58893
                     /gene="rsfS"
                     /locus_tag="PC465_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HDF2648609.1"
                     /translation="MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASS
                     QRQVKAIADNVEDELAKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEK
                     LWKDAPYIDIDTLA"
     gene            59247..61667
                     /locus_tag="PC465_001287"
     CDS             59247..61667
                     /locus_tag="PC465_001287"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HDF2648610.1"
                     /translation="MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYP
                     SGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTM
                     ENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCP
                     SCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDTLDGWPEKVKT
                     MQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTE
                     YEADVETFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYG
                     TGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLE
                     KEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTG
                     KGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKEL
                     VNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSK
                     MSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLV
                     DELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDM
                     YKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKA
                     LVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPK
                     KLVNIVVK"
     gene            62503..63171
                     /locus_tag="PC465_001288"
     CDS             62503..63171
                     /locus_tag="PC465_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDF2648611.1"
                     /translation="METVTNNQSGVEIQLSLFEAIKDLLLINPIFLLGIILIGIFLVV
                     IFKKNSDIPKVKTSILSLAMYYYLCLTLSHIVGIPTFGEYIRLSQLGETFFNPNINLI
                     PFSDGFSLSFILNILLFVPLGFLCPLISKTFERLRNTFLIGFGLSLFIETIQLFTLHR
                     ATDIDDLLTNVIGTIIGYFCFKLIAKLRIVKLHSDDDSMEQDYTVCIPIAIIIVALIL
                     GFFS"
     gene            63211..63291
                     /locus_tag="PC465_001289"
                     /pseudo
     CDS             63211..63291
                     /locus_tag="PC465_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005541856.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(63654..63926)
                     /locus_tag="PC465_001290"
     CDS             complement(63654..63926)
                     /locus_tag="PC465_001290"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2648612.1"
                     /translation="MSKHQFKSVSTFFTKKNVSQFYKKNNLKKIRIHDLRYTSATLLL
                     LGGTNMKVVSERLGHTDIKITMNRYSHVLKEMDKEASDNLSELLFK"
     gene            complement(64157..64578)
                     /locus_tag="PC465_001291"
                     /pseudo
     CDS             complement(64157..64578)
                     /locus_tag="PC465_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(64597..64695)
                     /locus_tag="PC465_001292"
                     /pseudo
     CDS             complement(64597..64695)
                     /locus_tag="PC465_001292"
                     /inference="COORDINATES: protein motif:HMM:NF026008.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
     gene            64978..66348
                     /locus_tag="PC465_001293"
     CDS             64978..66348
                     /locus_tag="PC465_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp29"
                     /protein_id="HDF2648613.1"
                     /translation="MKLKKLLSLGLAVSMFAAGPISANALDTIYTIQGKDKYETAALI
                     ADEQNYTTAILINADSTMADGLSASGLAGATNAPIFLTKKNNIPNATLKRVEKAKKVY
                     IIGGESSIDKATETLLKDKGIEAKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAFK
                     GEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGVESYVIGGTSSMSDKLVNDTNSTRL
                     GGVDRYDTNKKIVNKFYNGAKEFYIASGTDLVYALVASPMAKNNPIVLVDIGSNKDIL
                     KNAAKVTGIGNLSDKIMLECENTINNISLPSSNKNIICGLKIDFDSKHIIWQDKGSYL
                     ECYDDNLEYYTEKYKDPTVPINIENTSTQNLDVTKLKVYGEANSTLYMGQYAKIKMDF
                     NSFGVLKPGEKCTIYLDIISLDPSRSMTLTFSYVGDKENYKYEQGLASRILFYNPDGE
                     DFFEYK"
     gene            66707..66865
                     /locus_tag="PC465_001294"
     CDS             66707..66865
                     /locus_tag="PC465_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648614.1"
                     /translation="MDNFLQGILASLSASLIVYIASKLFRKRKKPLKAATKSGWEFDL
                     KIRFHKTK"
     repeat_region   67151..67646
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=67151..67179
                     /rpt_unit_seq="gttttatattaactatatggaatgtaaat"
     regulatory      complement(67788..67885)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            68111..68494
                     /locus_tag="PC465_001295"
                     /pseudo
     CDS             68111..68494
                     /locus_tag="PC465_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            complement(68683..69678)
                     /locus_tag="PC465_001296"
     CDS             complement(68683..69678)
                     /locus_tag="PC465_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HDF2648615.1"
                     /translation="MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNID
                     KVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFL
                     DLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLA
                     SEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYV
                     GENADFIRFAVDSGYKGIVIEAMGRGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVF
                     DSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTDNLDEIKDFFEKGIYC"
     gene            complement(69799..71427)
                     /gene="aspD"
                     /locus_tag="PC465_001297"
     CDS             complement(69799..71427)
                     /gene="aspD"
                     /locus_tag="PC465_001297"
                     /EC_number="4.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 4-decarboxylase"
                     /protein_id="HDF2648616.1"
                     /translation="MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAG
                     RGNPNWTCSTAREAFFTFGHFAITETRSNWDLGHLAGMPQKKGIKERFFKFINENIDM
                     PGAYLARDIINFGINELGFDGDEFVHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQE
                     MKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPN
                     LPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDET
                     SCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWR
                     LGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNH
                     TAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAA
                     YYTQFDIEEWAKLNYGEGLFKFISKNASPVDVLYKLANDYSVVLLSGNGFYGPEWSIR
                     ISLANLYDEAYTKIGKAIREILNGYIVEWQKIKK"
BASE COUNT        27212 a         8342 c        11729 g        24270 t
ORIGIN      
        1 attttaatat taagtatata aaacaaaatg aaaaaatatt aaatttaaac tagaaggagg
       61 tttctaagat ggacattaaa tacaaataac cagaacaaaa gatataaata tatatataaa
      121 tggaaaaact tctatcatat tgtataatca tatatgtaaa gaaaatttat aaattaatat
      181 aaaggagatt agaatgaatt catataatat tttggtggta gaagatgaaa aggagatagc
      241 agatgctata gaaatatatc tattaaatca aggatataat gtttttaagg gatacaatgg
      301 attagaaggt cttaaggtta tagaaaacca agaaatacat ttagctatag ttgatataat
      361 gatgcctaaa atggatggta taacacttac aatgaagctt agagaaaact ataattttcc
      421 agtaataatg ctatctgcaa aatcagagga agttgacaaa ataatggggc ttaatatagg
      481 agcagacgat tatgtaacaa aaccttttaa gccattagaa ctattggcta gagttaattc
      541 acaacttaga aggtacacta agtatctaaa catggttgga aataaagagc aaaaggtaga
      601 aagtgacgat agtgtgtttg caataggcgg attagaatta aatgaaaata caaaagaagt
      661 tagtattgat ggaaagtata taaaaacaac tcctatagaa tttaaaatac taagtttact
      721 tatgagaaat gcaggaagag ttttttctgc tgatgaaata tatgaaagag tttggaatga
      781 gaatgctgta aatacagata cagttatggt acatgtgagg aatataaggg aaaagataga
      841 aattgaccca aaaaatccta aatatttaaa ggtggtgtgg ggtgttggat acaaaattga
      901 aaaaatttaa agataaatat atagttacta ttatagtttt tatacttatg ttatcagcat
      961 cattaggtat gattagtcaa tattctacta tacaagcaag tgctaaaggt ggagcagaga
     1021 atccatttga acaggaaagc tttgtagata gtatatataa aggaagttat gttttatatc
     1081 ataatatgaa ggaagaacaa gaaggtaaga tgatacaacc atcaaagcta tttatcaatg
     1141 aagaaactat gaactatata aaaaatgtaa gtaaagaaaa agatacttat gatggttcag
     1201 aaacttacta tacagatgat agtattaatg cagattttaa tgaaaacttt gaaaattggg
     1261 agcatttcat taaagcgtca ggaaagaatt taaagtacta tttagttgat aaagaaagca
     1321 attttgaatt ttttaatgat aataaagaat taggagtact tgatacaaca aagaatgatg
     1381 cttcaaaaga aaattctgat gaaaatcagt caaaaaatac agaaatgaat gatgaggaaa
     1441 gacaaaagca gattacagat ataaaagaaa actatagatt ctacgttgta atgaattttg
     1501 ataaagatgg aaaagtaaat attgtagatt cttatggagt aaatcaaaaa gttattaatc
     1561 aaatgttgtt atctaaagca agagaagatt taatggatac aagtttagga ggaaattcaa
     1621 tttcatataa gttatctcca ataaaaaata taacattagt atatgctgta cctaaagcaa
     1681 taagtaaagg tgatagtgta gagtatggtt atggaaatac ttattttgat gatggtataa
     1741 tttcatatat aagcaatgta gaaaataatt cttattataa gatttctgga atgattttaa
     1801 aaattatatt agctatagtt gttattgtag ctttagcatt cccatataga aaatctaaag
     1861 agttgctagg atttgataca ttatcaagaa taccgttaga gatactcttt attgctcttg
     1921 ctattataca ggggcttgta gatttatatc ctactgttat aataagtaat accttgagtg
     1981 ggaattatgt agagtacctt ataaacaatg acataagtgc taaaatggct agcatattgg
     2041 taagtttaat gaatttaact tattggtttg taatattctc aataatattt gtatttataa
     2101 tacttttaaa acacatttta aatgttggaa taagagagta ttttacaaaa catactatga
     2161 caggaatgtt ttttgtatgg ctaaaaaaag caggaaaaac agttattaat caaattagaa
     2221 caataaatct aaaagaaaag ccaaataaaa ctatagttac aattttggga ataaatttat
     2281 tgattatagt tataatgtgt agtatgtggt tctttggaat aatactcgca ttaatatatt
     2341 cagtagtatt atttaagata ctgtcagatt actctaaaaa gacaatatat gaatataatc
     2401 aacttttaga tgttacaaag aaaatttcag atggaaactt agatgtaaat atggaaaaag
     2461 atttaggatt ttttaatcct ataaaagacg aattaggaaa tattcaaact ggatttaaaa
     2521 aagctgttga cgaagaggtt aagagtcaaa agatgaaaac agagcttata tcaaatgtat
     2581 cacatgactt aaaaacacct ctaacatcta taatcactta tatagattta ttaaaagatg
     2641 aaagtataac agatgaaaat cgtaagttgt atattgatac attagacaga aagtcacaaa
     2701 gattgcaaca tctaatagaa gatttgtttg aagtaagcaa ggcaaatagt ggagatgttt
     2761 atttgaatat agtaaatgtg gatattgtat ctctaatgaa gcagacactt ttagaattag
     2821 atgacaaact tgcagattca tctctaatag taaagaataa cttttctaat gaaaaaataa
     2881 tattaccatt agatagtcag cgtacattta gagtatttga aaatcttata ataaatataa
     2941 gcaaatatgc aatgccaaat tcaagagtgt atattgatat tttagaaaca gataataaag
     3001 taaatattat gcttaaaaat atgtctgcat ctgagattga ttttagtgta gatgatataa
     3061 tggagagatt tgtaagagga gataaatcac gtaacacaga aggttctggt cttggtttag
     3121 cgatagcaaa aagttttata gaattacagg gtggtaagat gaatataagt gtggatggtg
     3181 atttatttaa agttacaatt acttttaaca aaaattagat tagacttatt taataattat
     3241 aaagtctata gaataaaaga gtctggaaat atttatgtgt attctttaaa taaaaattta
     3301 taggtattgt tttaaaataa tttgtaagca ttatttcaaa acagcttata aatgttattt
     3361 taaaacagaa tgttgattta tttaaaaaag gtgaatccta atatacaagg ttcacctttt
     3421 tattttacaa aatgttattt agtgttacag agcttataaa tagcataata tctgggttta
     3481 ctattaacat agtactagca atttattttg aaatcttgta taagctattt tatattattt
     3541 aattactatt gtttgtactt tacaatgtga taaagaattt acctctacag ttttagtatt
     3601 tactttaagc ttgctagtat tatcatagat ttcgtcgagc attgcactat aagcatcatt
     3661 gacattttta ttgatgttaa gacttccctt agcatcctca tttttcatac cattgaagat
     3721 tctaactaca attccatctc ctttttcttc tttctttatt gcacttactg tgaaatttga
     3781 attatttaca ttcatcaaac tatattcatt ttcatatatt tgtttttcgt cattgaatgc
     3841 aaatataagt ctaccattta aaaaatcagc atattcatat atttgtatag gtgttaagaa
     3901 tctcttagct gtattagcta catttgcttc atcaaattta ttgttatata tgtaaagacc
     3961 aaagtcaaag tttaactctt taagtaattg tgcatctggt gttgctatta ttttttctcc
     4021 agaagctctt cctggtctat aaagtaaatt ttctcttccc atatatccaa atgacctgaa
     4081 tagtgttaat gctattgtat ctaaattatc accaactatt tgatattctc ttacacaacc
     4141 agttattaat gctattcctc tttgtccatc ctctaaagta acaaaacttt gcattggttc
     4201 gatagttata ggtttttctt gccatgagta attgtctctt ttccacaatg caaggtcttt
     4261 ttctaatact gttggtcttt gtattattcc aaattgttga tctgctatag aaaacttaga
     4321 tgctatttct gtattaaata aaactcttac tctatgagat agtgcttggt tattttttat
     4381 attaacatta aacttaatta tttgttcttt aggttctaag gtaattttca ttgttactgg
     4441 cattttcaca gaaactttac ctatagccct ttcttccagt gaagctggta tggtcaatga
     4501 atatttaagt atcatttctt cttgaatgtt tgattttagc acttctactg aagatacaga
     4561 atctaaagat gaaacataaa tatcttttct tggaggagaa tagttgtatg aatctccatc
     4621 atctccatta tcttcaatta cagcttggtt tttataagtc ttattagatt ctttatctaa
     4681 tatttctaat gaaccatttt tattggctgt tattttgtag tatttgtttt ctatttcttt
     4741 gcaattactt gtttctattt cacatttatt tttagtatcc aattcaaaaa ctagttgagt
     4801 atatcccatt ggtggtatat cttttactga aagtgcaatt tttgctctat atacagtttt
     4861 gggtatatat atttttttac ttgggtttaa tcttattgtt tgagttaata tataatttgt
     4921 aatatcttct ttttctttta ttatataatt aagaatttct ccatttttat tctttatcac
     4981 aaaatcttga cctggaatat aagtatcaaa ttctacaact tcatttctga cttctgggaa
     5041 tccattgaat actgttaatg ttatttcttc attattattt ttgatttgag tacttataag
     5101 tctcatatgc aaatctaata aatttatact caaatctctg gcttgtttgt atcttgtgta
     5161 tacatcctca tttgttgtgt cactattaca agaacctatg ctgtcatgag ctgcattttc
     5221 aaacataagt ttccatatat cttttataac tagatgaggg tattcatttc caagtgaata
     5281 acttaatgtt aataatggtt caagtacatt tgtaatataa ttttctaatt tgttattcat
     5341 tattttaagg tctgaccttg aggagaatat ggatttgtgt attctcatat gtttagcatt
     5401 taaaaattca cctttaagct ctgtaaattc atttctttca tttcttactg aatctatata
     5461 gttttctata tcacttattt cgtattcatt ttcattatct atttcattag ctttttttaa
     5521 tatatcagga aggttttttc ttattggtgc ttggtcaaat ccatttggaa aatatacgtt
     5581 attagtagaa gctttaacct taagttttcc gattatatct tttaaatatt cttttaaatc
     5641 tgaatcatct tctggtatat tacctccata gtaataacca aatggtattt gaactgctaa
     5701 tacttttgaa ccatcagaac ctttccatat aaactctgtt gtatctacca tatcatcaga
     5761 aactccacgc caaaataatg aactatctat tccaaaacct ctgtatattt gtggcatttg
     5821 agctgattgc ccaaaagaat ctggtacata tccaaccctc ataggttcac caaattcatt
     5881 gcatctatct attccatagt aaaggtttct aattatagat tctcctgata taaccaattg
     5941 gtctgtttga gtataccaag gtccaataac taatcttctt ctttgaacta aatctcttat
     6001 tctatattca tcctgaggtc tccattttaa ataatcatct aagagagaag cttgtgcatc
     6061 catagtaaag tatttaaagt cttctttttc ttccaatatg tctaatatat cttgaaaatc
     6121 tttcattaaa tatatttttg accttgatgt tgtaaaatac cattctctat cccaatgact
     6181 gtgtggaact acatgtactt ttgtcttttt cataaaaatc ctcccaaaat ttaattgaga
     6241 attgagagta cactcaattc tcaattatct aaaattaagt ttttaattta cattatatct
     6301 aactctattt catcaaattc tatattttcc gtagtttcat cttcattgaa gtctactaaa
     6361 gttgttgata gtattgctat tactaaagct ccaaatattg cacctactaa gtaagcccat
     6421 ccagaaccta ttgatataaa tccatataat ccaccaactg gaggcattat agcatgtaca
     6481 cctaacaaag ctgataatcc tacacccaaa gcgcatccta tcatattaac aggaactaat
     6541 tttaatggat ttgttaaagt gaaaggaatt gcaccttctg ttattccaat tatacccata
     6601 actatattgc cttttcctgt ttcagctaat gcattggaaa attttgattt tcttatgaat
     6661 gtagctaaac catatcctag tggaggtata actattgcgc agtttaccaa tatcgctggt
     6721 agatagattc cctctaacaa taatgcattt cctgccatcc aagctgcttt atttactggt
     6781 ccacctaaat cgaatcctat cattgcgcct aaaattaaag ccaataccac cgaatttgtt
     6841 ccattttgac acatttcagc tacccaagca tttaatgaag tatttatgtt tcctaaaggt
     6901 cctgctaata caacactcat taaaaaacca gttaatccaa ctgttataag tggcattatt
     6961 ataagtggca tcattcctga tgctgaccca gatattttaa tttttttctt taaaaactta
     7021 caaacatacc cagcaaagaa acctgctatt actgctccta agaatcctgc attagtatta
     7081 cttgctatga gcccaccaat aaaacctgca cccatagctg gtttctcacc tattgaaaat
     7141 gctataaatc ctgctaatac cgtatttaat agacctatgc cagtccaacc aacttgttcc
     7201 attaagtaaa gaatatgata aaaaccagat acatttttat aagcatctaa acttgttata
     7261 cccactgcta aagctgtaag ctttgggata gctacaacta aagatgagcc tattacaagt
     7321 ggcaacatat atgagatacc tgtcattaag tgtcccttaa gttcacttaa aagagattta
     7381 ttttttttac tcatttttaa tcctcctata taagtttgtt atattttttg ataatatgtt
     7441 ataattatat tagacaattt tttaattttt gatttttctc attctatatt agagtgagat
     7501 ttttttatta agaaatagct tctatacact ttgttaagac agcttctggt ttttttaacg
     7561 ctatacctat tttgactttt atcacttttt taccatcaaa tctttccatt ccagatatag
     7621 tttggtcaga tgctataagt ataaagtccg catcttgtgc ttcttctttt gttatagtat
     7681 ttactcgtcc catagcacct tgttgttcta ctttgatttc atgacccatt tttgatgcag
     7741 cttgttctaa agcttttgct gccataggtg tgtgtgctaa tcctgctata catgatgtta
     7801 ttgctactat tttcataatt attcctcctt cattttatta gttatatatt ttactaaatg
     7861 acttgcatca ctagcatttt taacttcact tgtaaaatca tcctccatta aacatgtggc
     7921 taatttagat agagttttca aatgtatatt tccttcattt ttatgtgggg ctaacaaact
     7981 aaatacatat ctaaccttac tatcatctaa agttttccac tctaactcgt tagttgtttt
     8041 aatatagagt atggaagctt cctttacatt tacactcttt gtatgaggta tcgcaaatcc
     8101 atcttttatt cctgttggaa attcattttc tctttttaga aggtctttta aaagagcctc
     8161 tttattagtt gtaataccta gtatataagc actatctgca ataaaattta atacttcttc
     8221 tttgcttttt aagtctttat ctataaatat atatttttct tgtagtacca tatatttttc
     8281 cactccattc ataatgtctt aacttatatt tatattgtaa tcattatcct aattaaatta
     8341 aatataacta atttccactt cgacatggaa atttatatta tgataataac taatttccat
     8401 atagaagtgg aaataaatta ttataataca attttattag agtaattgta ttatattagt
     8461 gtaaatagta taatttagaa gaaattctat aaggggggat atttatgcac aagagattgc
     8521 tcacgttgtt taaattatta aatgaaagtg atgataaaat tacttgtaaa actttaagta
     8581 atcatttaaa agtgagtgag agaactataa gaaatgatat tacttctata aatggaactt
     8641 tagagaaaaa tggtgctatt attaaaataa aaaaaggaga aggatattat atagatattc
     8701 ttaatttagc attataccaa cagtatctag cattaatatc tgatgatatt atggattcaa
     8761 gtgaaatacc agattctcct atagaaagaa atcaatatat tttaaaatat attctctata
     8821 acaatacata tataaaacta gaagatttag ctaatagctt gtatgtgagt aaatttacaa
     8881 tactaaatga cataaaaaga ataaagccta ttttgtcaaa gtataattta atattagttt
     8941 ctaagccata ttatggagtt aaagttgaag ggaaggaaat agatattcga agatgtattt
     9001 ctaataatat gataaatagg aattttgaaa actatataat tggaattaca gatagagaaa
     9061 tagaattatt taataatgta gatttaatag agcttcaaag ggtagtgtta agtgaaatta
     9121 ataaatttaa tatcaatttc ctagatttta atctaaaaaa ctttattatc catttagcta
     9181 ttactgtaag tagaatactt gatggttact gcttagataa tgttttagat gttgttttaa
     9241 cagattttca atcgaataca actgttgaaa atatatttaa ttatattgag agcaaatata
     9301 ctataattat ttcaaaggca gacagagttt atctatataa tcattttata actaaaagtt
     9361 ctcttttgga taacgtttcc aatagggtag atactaaaat tatagagtat gttgaagaaa
     9421 ttttagaagt aatcaacaat caatatactt ttgaccttag aaatgatagt gtattatttg
     9481 atgatttagt actgcacttt aaatcaattc tcaattctaa atcttataat ttaaataagg
     9541 tgaatcccct tataaataca ataaagagta attatccttt agcatttgaa ataactttaa
     9601 atgctataga aaaagttttt aaaaatagta tttactcttt aacagaagat gaaattggat
     9661 atgtatccct gcatataggt gctggaatag agagattttt tcaaagtaat attaagtgta
     9721 aaaacgtagt attagtatgt ggttcagggt atggttcaag taggttatta gaggttcaat
     9781 taaacaaagt ttttcatgat aaaataaata tacttcaatg tctatcattt aatcaatttt
     9841 tagctagtga attgtcagat gtagatataa taatatcgac aattccttta aatcatgata
     9901 gtattcctat tgtattagtg gatttaaaac tattaaaaaa agatatagag aatatatcta
     9961 agtcaatcac taataattcc catatttata gtaatctttt ggacaatttc tttgataaaa
    10021 atttatttat tgttaatcct aaaatcaaag ataaagatga gcttataaag ttgatgtgca
    10081 acaaattaac tcaaagtgaa attgtatttc catcatttgc tgaatctgta ttttacagag
    10141 aaagtttatc ttctaccaat atagatgatt ttttagctat acctcatcct atggaattaa
    10201 gctctataag aactaagatt tgtatttcca tattggatga accaatatat tggagtgaag
    10261 attctactgt taaattaatc atgatgttgg ctataaataa agatgattat ataaaaataa
    10321 actccattta tgatatcctt ttaaagataa ttcatgacaa tgatattaga gatagtatat
    10381 ctaattgtaa tgattttgat aattttcttt ccataatcaa gtctatagta tagattttta
    10441 tattacataa gttttaaaaa ctttaataaa atattttttg tttttagcat aaatagtata
    10501 agtaagtttt gtataatttg ttattatttt gtattgatta taattattat acaataaaga
    10561 ttctgtctca aaatagagag agaaacctgt ttttcattga taaaatgata aaaatatatc
    10621 tgatttcata caaaaaagag tgtctcatga actaaaaagt tcattttgag acaccacctt
    10681 tattatttta tattatttat ctcttgtata tattactata gcatccctta aaaacttagc
    10741 taatccaggt tgttctctat cataatatga tgtaaaacgt tcatcatata catacatctg
    10801 tgctagagag gaatgagctt ctttagagta tgtgttccaa gtgtaactca accatttatg
    10861 atgtaatttt gcaacttcct gagccagttc actagaggca tcaccagttt taaaagcttt
    10921 tttaagttta ctaattattt cgatatttag gttttgccaa ttttcataat cttgcttaga
    10981 catattttta agttttttgt ttgatgtatc tataatatct ttaccatatt tctctctaat
    11041 ttcagttcca taattttttt cattttcatc aatcatcttt tctttaaaac cttcaaattt
    11101 ttctatatct gtcatagtgt attttccctc cttcagagct atagttttag ttacattttc
    11161 tattagtaaa tcaatttgct ttcttttggc tagtaattta ttatggtgtt cttttaacgc
    11221 acttaaacta tcgaagtttg gtgaatttat aatgtttttt atattttcta agttaattcc
    11281 taattctcta taaaaaagta tttgttgaag tttattaact tcattttgac catatatacg
    11341 ataacctgaa gaatttattt taagtggttt aagaagacct atttcatcat aatatctaag
    11401 tgttctagta cttataccag ctagtttact taatttttga actgtatatt ccataagtag
    11461 tacctcctat aaattaaata tacactttta cgcaacgtaa atgtcaatac attaaaatat
    11521 aaaaatttat atcttttaat aaaaatataa aaaaatatct ttactggata ttttacacac
    11581 aactgtcaat actcactaat gaaaattaaa aaataaaatt tatagactat ctttactaaa
    11641 aaatagaggg tctatagtct aggaggaact gtatgaattt aaaaagaagc aatgaaaaac
    11701 gagaagagta cagaagaatg tattcagata aagaaagttt tttaagtttg attcaaaatt
    11761 ttacaagtgt ctcaatagca aaagaattaa ctcttaaaaa tatagagtta gaaacatctt
    11821 ttatatgtga atataaagga aaagaagttg atataattta taaggtattt tctaaaagcg
    11881 gcaaagtatc acattatata gtgttagaat ttcaaacaga aatggatact gaaattgtcc
    11941 caagattgaa atcgtataga gaacaaattt ggaaaagttt tattatgaaa aaaagccttg
    12001 aagaaataga agataaaaat tttaaacttc ctaaagttat accagttgtt ttatatagtg
    12061 gacctgaaag gttaagtaga aaaaaaggaa ttttggatat tgtagaatct atatcggagt
    12121 tcagtaataa ttctagtatg aaaaattaaa attacataat gtgtttattg gtctaaaatg
    12181 gaaaactgtc gcataaactt gaatatgaaa atatttatag atacaggttc tatgtggagg
    12241 tgttccatga gaaataacaa gtctaaggta ttgctaggaa tactttgtct agcaacagga
    12301 atggctgtaa ttctgtcaat gttgcttcct ggctggattt ggtcagcact taccgcatta
    12361 atacttattg gatgtggagc attattattt ttttgttaaa atagttttaa ctataaagtg
    12421 tggggtgagt attgatgaaa gtagtaacaa taaaattacc aaaatggatt tcaagtataa
    12481 tcctaaaatt tatgagaaag agtaaaaatg attaaattaa aaagcctact tacggaagta
    12541 ggcttttaaa cgtggttact aagctctttc aattttacca gaacgtaaac atctagtaca
    12601 aacttttact ctcttaggag ctccatctat aatcgctctt acgcttctta agttagctga
    12661 ccatgttctt ttattatgtt tatttgagtg tgatacttgg tttccagaaa ccttaccttt
    12721 accacatacg ctacatactt ttgccatcta cgcacacctc cttaaaatga taactattta
    12781 aagactaaaa acatatttat attatcataa ataacaaaaa tttgcaatag aaatatatat
    12841 ttgccttaca catattgaag aatttcttat tatcatataa aattatatat ataattttat
    12901 ataaagtaaa tatatttgga aaataattat tatttttctt tgaatatata tactatagaa
    12961 gaaattttat ccaaaaactt ttctaggttt aaattatacc atatttatag tatgatatga
    13021 ttataatttt atataataaa taagtaaaaa tagtaaaaaa taaattaaga aatgttttta
    13081 ataaaaataa gcttaagggg gtcaaccatg agtgcaaagg taacgaatca atatggaaat
    13141 atagaaatag ataatcaagt aatagctcaa gtcgtatata gagctgcaat ggaaagttat
    13201 ggcttagtag gtttagcata taagtctaaa ggaatagtag agctattaaa aggcgagaac
    13261 gcaactaaag gtgtaagagt tgaggaagta gaagaagatg ccatagcaat cgaactttat
    13321 gttataatac aatatggtac aaatatatct actgttgcca ataatataat agatagagta
    13381 aaatatgtag ttgaaaaaat gactggcgta agagttacta gaattgatat taatgtacaa
    13441 ggaataagag ttaagtaatt tcataggagg aaacaaatga ttcaatatat agatggtaaa
    13501 aggttaaggg agatgtttat ttcaggtgca aacaatctcc aaaacaataa agagttagtt
    13561 gacaagttaa atgtattccc tgtaccagat ggagatacag gaactaatat gtcattaaca
    13621 atatcttatg ccttaaaaga attagcaaaa gttgaaaatg ataatatatc agatatcgga
    13681 aaagcattat ctaaaggttc tttaatggga gctagaggaa actcaggagt tatactttca
    13741 caaataatca gaggtatagc taaatctata gaaggaaaaa gtaaattatc aacagaagat
    13801 ttagcaaaag cttttaaaaa tggttcagac acagcatata aagctgtaat aaaaccaatt
    13861 gaaggaacta tacttactgt agttagagaa agtggagagt ttgcaataaa aactgcgaaa
    13921 aaagagaaag atgtagtaaa gtttttaagt atgcttgtga aggaatcaaa ttcttcatta
    13981 gaaagaactc cagaccttct aaagaatcta aaagaagctg gtgtggttga ctctggtgga
    14041 aagggtcttg tacttatata tgaaggaatg ttagcttcta taaaaggcga taacatagaa
    14101 ataaaaaatg ttgacctaga tactaatatt tcaacaagta tggattttac aaagagtact
    14161 actagcacag atgatataaa atattgctat tgtacagaat ttattttaga aagttctaag
    14221 gtagaagata ctaaaataag agacataatg atggcttatg gtgatagcct agcagtagtt
    14281 ggagatgatg gagtcataaa ggtacatgta cacactaatg acccaggaaa tgtacttcaa
    14341 gaagctctaa agtacggtca attattaact ataaaaatag aaaatatgaa gttacaacat
    14401 gaaaatacat tactggatgt agaagaaaag aaagaaaatg atagtgaacc tttagaagaa
    14461 gaaaaagagt ttgggtttat agctacttct atgggtgaag gtttggcaaa tatatttaaa
    14521 gatttcggag ttgaccatat aatagaaggt ggtcaaacta tgaatccaag tactgaagat
    14581 tttatgaatg ctataaagca tataaatgct aaaaatatat ttattttccc aaataacagc
    14641 aatataataa tggctgctaa tcaggcaaaa gaattgagtg ataaaaatat aatagttata
    14701 cctacaaaaa atacgcctca aggatttgct gcattagtaa cttttaatgg agaattaagt
    14761 gaagatgaaa ataaagaagc tatgatgaat gctttaaact cagttaaatc aggtcaagta
    14821 acttttgctg ttagggatac agtgatgaac gaaattgatg ttaaagaagg taatataatt
    14881 ggaattgcag aagggaattt attatcagca ggagattatg tggatgaagt aacatcaaac
    14941 cttattgaaa agttggttga tgaagatact gctataataa cattattctt tggtgaagat
    15001 gttacagaat ctcaagcaaa tgaactacgt acttctttag aagaaaagtt tgaagatgta
    15061 gatgtagagt tatattatgg aggacaacct ctttattatt acttaatttc agttgaataa
    15121 tgattataag aacctgtatg accaagtagc ttttataaaa ttggttgtac aggatttttg
    15181 tgtagtaggt gatatatttg ttggatttat ataaagatgt tcaatatgtt aagggaatag
    15241 gacctaaaaa agcagataaa ttaaataaac tgggtatatt tacactaaaa gacctattgt
    15301 attattttcc aagacaattt gaagatagaa ataatctaaa gaaaatagca caattagaag
    15361 atggtgagaa agttacgata aaagcagtaa tatcaagtat aaatacattt agcccaaaag
    15421 aaggtatgac tttaacaaag attgatgtaa aagatgagac aggctcggct aaattagtgt
    15481 tttttaataa gagttatata aaaaatactt ttcgtccagg agattcaata ttagtttttg
    15541 ggaaggttaa gaaaaaattt aataacttag aacttacatc atgtgaatta gaatatctta
    15601 ctaattcacc taagaataca tgtagattta tgcctgtgta ccagcttaca tacggtgtta
    15661 caaataaaga aattatgagt ataattagaa cagtacttga agataaagaa ttaattatac
    15721 aagaatatat gccacaaaga attatagaaa aatataggct atgtagtata gattttgcag
    15781 ttagaaacat acattcacca agtagtaagg aatcattaaa aatagcttta tatagaattg
    15841 tatttgaaga attacttata ctacaactag ggttgtttgt atttaaaagt ggcagaaata
    15901 aagaagatgg aataaagttt gaaacaagta aagacttaaa aaaaataata agtgctttac
    15961 catttaaact gactaaagct caaaacaggg cattagatga aattatacaa gatatgaatt
    16021 tagagaaaat aatgaataga ttggtacaag gtgatgtagg gagtggtaaa acagtagtag
    16081 ctctcttagc acttgcaaat tgtgttttaa atggttatca gggcgctttg atggcaccta
    16141 cagagatatt agcagggcaa cattatattt cacttactga gtctctaaaa gattttggaa
    16201 taaatgtagg tctattaata ggtagtctta caaaaaaaca aaaggataca gtattggaac
    16261 aaataaagaa taatgagatt gatatattaa taggtacaca tgcactaatt gaagataagg
    16321 ttgaatttaa taatattggt ttagttataa cagatgaaca acatagattt ggtgttatgc
    16381 aaaggagcaa actttcattg aaaggagcaa atcctgatat attagtaatg acagcaacac
    16441 caataccaag aactttagca cttatactct atggagattt agatatttct attatagatg
    16501 aacttcctcc aggaagacag ccaatagaaa caattgctat tgaaaaaagt aagcgagata
    16561 gagcatataa taaccttgta agaagagagg ttgaatcagg aagacaagtg tacattgtat
    16621 gtcccttggt agaagaaagt gaagccatag aagccaaatc agcagttgaa cttgttgagg
    16681 agttaagagc agaatatttt cacgacttaa ggcttgggtt gcttcatggt aaaatgaagt
    16741 caagtgaaaa agatgaagta atgagacttt ttaaaaataa agaaatagat attttagttt
    16801 caacaacagt aatagaagtt ggtgtcaatg tgccaaatgc aacattaatg ataatagaaa
    16861 atgcagaaag atttggactt gcacaattac atcagcttag agggcgagtt ggaagaggta
    16921 gtcataaatc gtattgtgta ctaatttatg attctaaaac agatgtatgt agacaaagaa
    16981 tggctataat ggaagagacc aatgatggtt ttaagatttc agagaaggat ttagaaataa
    17041 gaggacctgg ggaatttttt gggacaaggc agcatggtct tccagaactt aaggtagcaa
    17101 acttgtttaa gcatataaaa atactgaagt tagcacagca agaagctcga tatatattgg
    17161 gtgaagataa taatctacaa ttaaaagaaa acatggcact caaaaaagaa attatagata
    17221 aatttaaaga tacattgaaa gaaatttcat taaattaatt ttaaattgtg ttaaaatatt
    17281 actaatgtaa taatgtgctg aagggagatt gtcatattga gagtaatttc aggaaaagcg
    17341 agaggattaa aactaaatac tccaaaaaat gaagatgtaa ggccaactac agatagagta
    17401 aaagagtctc tatttaatat gataaattca tatataatgg aaagtgaagt tctggattta
    17461 tttgctggga ctggttcttt aggaatagag tgcttatcta ggggtgccaa gtcatgtact
    17521 tttgtagata tcagtaagga aagcatagat attgttaagt ccaatataaa aaaggcaaga
    17581 gttgaaagtg aaagtattat tttaaacctt gattttaaga ctgcaataga taaacttaaa
    17641 ttacaaaata gtaaatttga cataattttt atggaccctc cgtattataa aaatatgttt
    17701 atagaagcta ttgaaaaaat tgataattct aatctattga acgaagatgg aataatagtt
    17761 gtagaacatg atacgaatga tttatttcca gataagatat gtaaattgga gaaaactaga
    17821 gataagaaat atggaaatac tacattaact ttttataaga tggaggcata atatggaaaa
    17881 taaacctaga aaagctatat ttgcaggaag ttttgaccca attactaatg gacatttaga
    17941 tattatttgc agggcttcga agttatttga cgaattacaa ataggagtat taaataatcc
    18001 taataaaaag ggtctattta gctttgatga aagagtaaaa cttatagaaa aaagtacaag
    18061 ccatttaaat aatataaaag ttgtgacttt tgatggttta ttaataaatt actgtcagga
    18121 aaatgggatt ggagcattag ttagaggtgt gagaagtggt gctgatgttg attatgaact
    18181 tcagatggca catatgaata gagagcttaa tccagatata gagactataa ttttaccaag
    18241 ttgtacaaaa tattcattta taagttcatc tttaataaaa gaggttttgc tctttgatgc
    18301 tgatataaaa aatttggttc caaagattgt tttggaagaa ttaaagaaaa aaactagtgg
    18361 gggtaattga tatatgaaga tagatttaga aatgattgaa ctatttgagc agttagagga
    18421 gatatttaga agtgcttcta caatcccttt ctcacataaa tgcacagtgg ataaagatga
    18481 ggttttagca ataattaatg atataagaac tttaatacca gaagaagtaa cacaggcagt
    18541 atggattaat aaagaaagaa ataaaataat aagtcaagct aagcaagatg ctacaaatat
    18601 agttgaacaa gcgaaaaaag aagctgagag aatacaacaa gaatatcaag ataatataga
    18661 ggaattaaag aaaaattctg aagatgtagt aaaggcatat gtagaatcca gcgaacctgt
    18721 tgttcaagca gaccaaagag caaaagatat agttgataga gctgagagaa tagccaatga
    18781 gataagaatt gggtcaattg aatatgcaga ggatgtgctt tctagtgttg agtataattt
    18841 aagagaaata ttagaagaag taaaaagaga taaagctgaa cttagaccta aaaaataaat
    18901 tttaaataaa taaaaatgga gctatcacac aaaaaattcc aatttatgtg tgatagctct
    18961 cttttaatat agcaattttt tgttatataa ttgtgctttt tagattactt atatcttatt
    19021 ttgatattat aatgtagttt aatcttttat ttgttgaaat caacttattt atttgtataa
    19081 ataatatagg ttattttcaa atttttttaa taattttacc actgtcttct tttagattag
    19141 agttagactg tgcaaaatta taaaataata ctaaatcatg tgcaattatt tggtatggca
    19201 ctacatgtag aaaatataga taataaaatt aaggaggtag tatgaaggaa agggctaaaa
    19261 aaatattaga ttttattatt aaaaataaca atgtaacatc acaagaacta caagaaaagt
    19321 ttaatgtttc aaagagaact atttattacg atattctagc tataaataaa caactaggaa
    19381 aaagtggtaa tataaaaaat gtaaaacaca aatttatatt tgaaggtaat ttatgtgatg
    19441 caaggaaaat aatttcaact gaagaagata aatttttaga tagtgattac agaaaaactt
    19501 ttatattaaa caagatatta cttggcgaaa aaatatcaat agaaaaacta acaaatgaaa
    19561 tgttactttc aaaaaacaca gtagtacaaa caataactga tgtaaaaaaa taccttcaaa
    19621 caatgggatt aagattagag tataagggaa agtacaaaat tataggtgat gaatacgtta
    19681 ttagagagct gtttctgata attgttcaag aaaacgtact ggaaattaat tctataagtg
    19741 aggaagtaag tagtttcgat acaaaaggac atataaaact tactgattat tctttattaa
    19801 atctaactaa gtttgtggaa tttctaaata aaaggataag agatgggaaa acattatact
    19861 catataaata tctaaatgaa gctaaaaaaa ttagttactt tagtaattgt aaagaacttt
    19921 tatgtgaaga agctaatgaa aatgaacaag cctatatatg cacttacata agctcacttc
    19981 ccagcttaaa tagtgaagtt aaggaagatg ttgttgaaga atatgtagat aaacttatag
    20041 ataagtttga agtaaataca gcaataaaat tagaaagtaa gcatgagttt aagaaaaata
    20101 ttttaaggca cctccactct tcttacaaca gaatacgatt taagtttcct attagaaatc
    20161 caatgttaga tgagactaag tataaacatg agtcacttta taaaattata aaatcaatta
    20221 tagagaatga agaagagttt cctgtatttg aggggataag agaagaagaa ataggattta
    20281 tagcagcgta ttttggagga tatttaagag ggtctaggga taatggtcta agaagaaata
    20341 aagtcttact agtttgtcct aatggtctta tggtatcaaa gagtttggaa atacaactat
    20401 ataaatacat accaaccata gaaatagtag gtatagtatc cattaagcaa ctaaaagaag
    20461 taaatgtata ctacgattac ataattacaa ctatagatat acaaaatgta aacaacgtaa
    20521 ttgttgtaaa tcctctttta acatcatcag atgttcaatt acttatgaac aaactaataa
    20581 gtgtaaaaga aaacgagaag tatttcaatc ttgaattaat aatacaagct ataagaaaaa
    20641 atggagttat caataatgaa gaagcactaa aagctgattt attaaacata atacacaaga
    20701 tagatgaagg agagatgtat caaccaatgt taaaggaatt aattaatgca gaaagggtca
    20761 atataataaa aaatgttaga gattggaaag aagcaataaa aatagcctca aagccattgt
    20821 tagaagataa ctctatagaa gagttatata tagaaaatat gataaagtca gttgagaaat
    20881 atggaccata tattgtttta gctgatagat ttgctctacc acatgcaagt tctaaagaag
    20941 gagtaaacaa gcttgctatg tctttactaa tagtagaaga tgaagttgat ttattaggaa
    21001 aaccagtaaa tatatttatg gtattagctg ctgtagataa cactactcac attagagcat
    21061 tagcatcact atcagagatg atgtacgagg aagaaaatgt aaaactaata attaatggtg
    21121 ataaaagttc aatactagaa cttataaata agcaaaatta ggaggaatga aaaatgaaga
    21181 tattagcagt atgtggtttt ggtgtaggtt catcaatggt attaaaaatg acaatacaaa
    21241 aggctctaaa gcagttaggt atagaatgtg aagtagaaaa tacagatata aattcagcta
    21301 gaggtgctga ttgtgactgt atattcacaa gtcaagaatt gttaaatgaa ttaaaaggaa
    21361 cttgtaatgt agatgtatat ccagttaaaa agtacatgga tttagcagaa gtcacagaag
    21421 ttgttcaaac ttttttaagt gataaaaatg ataagaaata gtataagttt taaaaagtaa
    21481 atttaagtta atcagaataa aataaaaact tactaagttc aaaaatagta agaaagagag
    21541 gagggattta gtggtagaaa acttaaacag ttgacttatc actaaaaaat ataatgcttg
    21601 attttatttc aaataatatt ttacgtaatc catctatgtt aattggatta atagcagcat
    21661 ttggtcttgt actacagaag aagaaagcat ctgatgttat aaaggggtca ctacttgcag
    21721 ctttcggaat tataattatg gagactggaa caggtatgtt agttagttca atagcaccaa
    21781 ttaatggagc tttccaaagt ataagtggtg gtgcagtaac aaaaggttta agtgatgtta
    21841 cttttactgc aagttatggt ggaattatag gtttagcaat gtttgcgggt ttagctattc
    21901 acctaatgat agcaagattt actcctatta agacaatctt cttaacaggt cacatgcttt
    21961 attggttccc attcatattt gtagcttcag gagttgaagc tggattaaat ggtggagtat
    22021 taatagcttt tgcagcagta ttatcagcac tctattggtc aataatgcct tggttattaa
    22081 gaaaatatgt gtttgatgtt ataggagatg attcttttac attaggtcat ccatctggtt
    22141 gtttagcact tatatcagga tttgttgcta aattagtagg aaataaagaa aaatctacag
    22201 aagatataaa catacctcaa agtttatcat tttttagaga aatatctata agtggtggaa
    22261 tggcagtgtt tttaatgttt atagttgttg ggatagtaat accaggtgcg tttaaagata
    22321 gtaatgagtt tattggaacg tatgcaataa agcaaggtct ttcttttgga gcaggtctta
    22381 taataatgct tcatggggta agaatgctaa taaatcaaat aatgccagca tttcaaggta
    22441 tatctgaaaa agttgtgcca aatgcactac ctgcttttga ctgtccaata ttatttaatt
    22501 ataaaccaaa tgctgtatta ataggattct tagttgctat gctaacatct acagctatga
    22561 ttttaatatg taactacttt aatgtattta atttgctact tataccactt gttataactt
    22621 cattctttga gtgtggagca gcagcagtaa taggagaatc acaaggtggt atacgtggag
    22681 ctataatagg tacagctata gctgcaatat ttatggtagt tttagtagga atatctgctg
    22741 taatttactc aggaactatt caaaattgga tactaatatt tggaggtaat gacctttcat
    22801 tatttggtat aatcagtagg tttataggtt cactatttgg aggaatatta tagatatgaa
    22861 atttaaatac atagatgaga taagaagatt aattgatata atagaaaacg aagaaaaagt
    22921 caatatggaa aaagcagtac aaatccttgt tgaagcaata gaaagtaaaa atgctatatt
    22981 ttcatttgga gcttcacatg caggaatatt aacagaagaa ttattctata gagcaggtgg
    23041 ctgtgttctt ataaatccag tatttgcaaa atctctaatg ttagatacag cacctataac
    23101 tcacacaagt aagatggaaa gattagaagg atatggtaca gctctagctg ataaaactcc
    23161 aattaaaaaa ggagatgtag ttatagttca ttcagtatct ggtagaaatc cagtaagtat
    23221 agagtttgct atgaaagcta aggaaaataa ggcaatagta atatgtataa ctaatttaag
    23281 ttactcaaaa agtgtatctt caagacattc ttcaggaaaa aaactttatg aagtatgcga
    23341 tttagtgata gataatcatg gtcaaaaggg agatgcctgt gtagagatag atggattaaa
    23401 ccaaaaagtt agtccaactt ctactgtaat agcaactact gtgatgaact ctattatagc
    23461 tcaagctact caggaattag ttaataaagg gctaaagaat cctccgattt tctatagtgc
    23521 caatattgat ggtggagatg agttaaataa gaagattttt gatgaatata aaagtgtaat
    23581 tcattatgaa tattaaggtt aaaaaaatat gttaatgaac tttgaagttt atcaacaaag
    23641 aatattaata atatataata aatgctatca tttaaaagct gtaggtaaaa atctacagct
    23701 ttttattatt gtagattaaa aagatgcgta attaaatttt aaattggaga aaataaattg
    23761 gaaggtatca attataaata ttagaaacgt tgtcatagaa aaaaactata ttaaaaaaaa
    23821 gtacatagaa aaaactgatt agacaataaa tacatgcttt gataatattt taaatggagt
    23881 gaaaatgtgt agaattataa tgaaaaaaga aaataaaaat gaaaaaagaa aataaaatgg
    23941 agggaataaa agtgggtatg ttaaaaaaat tatgttcact agctatggta gcaattatga
    24001 ctacaacact tataacaggg tgttcaagtg gaaatggaaa agattcaaaa aaggatggcg
    24061 aaaaagaaaa actagttctt tggatgccac cagtagaaaa taatatgaag gaagtttggg
    24121 accctatttt agataaattt gaggaaaaaa ataactgtga agtagattta cagataattc
    24181 cttgggataa ttattctgaa aaatttgcaa cagctataag tgctggcgaa ggtccagatg
    24241 taggatatat gtatgcagaa atgtatccac agtttataga aagtggagca gtagaagatt
    24301 tgactaacta tgcaactaaa gaggataaag agcaatctat ttatataaaa acatctgaaa
    24361 tgatgggtgg aatgtatggt atgccattcc aagcagcaaa tccaggggta ttatactata
    24421 acaaggatat tttagagaaa ttaggagaaa aacctcctaa aacatgggaa gattttaaaa
    24481 gaatttgtaa aaaagcaacg caagatactg atggtgatgg aaagatagac caatggggat
    24541 tagctcaggg atggggagct aaaacttttg gtaacttaaa ctggaactgg tatccttatt
    24601 tatggcaagc tggtggagat atatttaatg atgatttaaa atcggttaaa tttaatgata
    24661 agagtggttt agaagcagct aagttcttaa aagaattaca agcatatgtg cctgaagatt
    24721 ctttatctaa agatagtaat gaaatgatag aaagtgtatt tggaccaggg aaagcagcat
    24781 ttacaataat gttatcttct gctgcaacaa gtgtatttga tgaatcattc ccggatttaa
    24841 attggggatt tgtaactgga ctagaagata agaaagcagc aacttttgga gcagtagacc
    24901 atttatcttt aatgtcatct gcgaaaaata aagaacttgc atacaagtta atacaacata
    24961 tgttaagtgt tgaatcaatg acagaatttc ataaagcaat accaagagca ccaataacaa
    25021 aaggtgaacc atatcaaggt gatgaaagat tcaaagaaat ggtggaaaat gacaaaaatg
    25081 tatatagacc attagtagta ggacctcatg gagttgaaat atatgaatat ttatggaaag
    25141 aacttcaaac tatgatttca ggagataaaa ctccaaaaca agcgttagat gatgctgcaa
    25201 aatattcaaa tgatttatta gcacaataaa agtttaaagc tgtaatatgt tgtaaaggac
    25261 tttacagatt aaaattagca ttgtatttat aaatacaatg ctaatattta tattggagag
    25321 gataaaatgg aaaacttagt tagagagttt gaagaaaatt caaaaagaaa aaaaacaaaa
    25381 ttaaatatta aaccatatat gtatatattg ccattgggaa taattttagt ggcgttttat
    25441 gtgataccaa taataatgtc aatatacttt agttttacaa agtataatat tattagtcca
    25501 gctactttta taggtttaga aaattataaa aaattattta cagatgaaac attaaaagta
    25561 tctattataa atactattaa atttactgtt gttgtagtac cttgccaaac tatattatca
    25621 ttgattttgg ctgtttggat tacaggaaaa ggaaatagta aaatagcttc atttgctaaa
    25681 ggtgctatat ttataccagt attatcatct atggttttga taggtatggt atggagggct
    25741 ttattgaatg gagaaggttc tattatatat caggtattag gtgcctttgg aatagaatca
    25801 tctaaacttt taggagatag taagacagca ttacctacac ttatgtttat atctatgtgg
    25861 aaaaatatag ggtatttcat ggtaatttat atttcagcta taatgaattt accaaaacac
    25921 tgctatgaag tagcgaaggt tgatggggct acaaaacttc aagaatttat aaaaataact
    25981 gtacctttat taaaaccaac tacaataatg gttgtatttt tagggtcgat atggtcatta
    26041 caagtatttg acttaattta tactgtgaca ggtggaggtc caggtatatc tactatgagt
    26101 atagttatgc atgcatttaa cttaaacttt aaaaacttta attctggata tgcaatgact
    26161 gtagcaaacg tattattttt gttaatagca gtagtttcga ttttacaaaa taagcttgta
    26221 agacgagaca attcagattt ttagaaaggt aggtataata tgaaaacagc aagaagatta
    26281 ttaagtgatg gtttactttt atttatagcg tgtgcaagtt tggtaccttt tatatacatg
    26341 ttgataatat cattgaagat aacatataac tcatatagtt tggatatatc tttttcaaca
    26401 gtaacccttc aaaactatat agatattttt actaaaaaag gatttgcaca atattttttt
    26461 aatacagcaa tagtatcttt ttcaggtgta ttattaaatt tagtatttag tacattagca
    26521 ggatattctt ttgcgaagat ggattttaaa ggtagtgata agttattttt atttatgata
    26581 atgactttaa ttataccttc ccaagttaca atgataccac tatatataat aatgaaacac
    26641 ttaggatgga taaatagtta tcttgcactt attatgccaa taccaactgc atttggcgta
    26701 tttataatga gacaagctat tttaggagta ccaaaagagt tattagaatc agcaaagata
    26761 gatggttgct cggattttag aattttaata caaatagtgt tgcctttaat taaaccagca
    26821 ttaattacac tagcaatatt tacttttatg ggagcatgga acgagtttat gtggcctctt
    26881 atagctacaa ctaaagatgc aatgagaaca ttaacagttg gattatctac tcttaagaca
    26941 ttccagataa ctaattatgg acagatgatg gcaggggcta caataacatt tttaccgcca
    27001 tttattttct atttgatttt gcagagtaaa tttgttgaag gtgtgtcttt gtctggtata
    27061 aaaggttaaa tagtctaatt taataatata taaagaaact tatataaata tggaggaatt
    27121 taaactatgg aaatttcata tgtactgaaa gattgcacat tcaaacacaa taaatattca
    27181 gttatagaag ctgaaacttg gaaagataag gatttggata ttgtagtagc taaaggtgaa
    27241 aaatttgcat ttcaaattat gttaaaagca acagaagaat ttaattgtac aattgataaa
    27301 agcagtgcta tatcatggaa aggcctagga aatagagtaa ggttagcatt aaatgtgcct
    27361 aatagtttag aaaataattt tagtataaat atattaggat atgttcaaga tgatacaaag
    27421 gcatttgtga atgatgctat tttaagggat aaagatgtgt tagtagagca atatttgcct
    27481 caaacatttt ggattgaagg tcaagtacca gaagattttg aagaaaataa ccttgatata
    27541 ggtattgata tatttaaaag ctttggatat gaagacgaag aaaaagtttg tacaattgat
    27601 gttcctgtaa aagtaagaaa tgttgtgcta aagcctttag atgaaagcaa gttcttttta
    27661 gatttatggc aacatccaag ttgtttagct agaatgtata aagttgagtt atggtctgat
    27721 atacattttg aaatagtcga taactattta aaagaattag catctttagg agaaaaagtt
    27781 gcaacagtta tagtttcaga ttatccatgg gcagggcaaa gttgttataa agtttataaa
    27841 aatccatcaa acttatatga atataacatg gtaagtgtat caaaaggatt ggatggaaag
    27901 attaaatgta actttgagag tatggatagg tatataggca tagctgataa gtataaaatg
    27961 gctaaggaga tagatttatt tggtctatta ggtaattggt gtgctggtga gtttggaaat
    28021 cctgtagaag gttataagga ccctataaga gtaagatatt ttgatgaaaa ggataaagta
    28081 tttaaattta taaacaatac aaatgattta aaagaatata taggattagt attaaatcat
    28141 ttaatagagt gtggattatg ggacagagta aggattatag ctgatgaacc aaataatcca
    28201 gaagtagtca aagagtgtat agaatttata aattctactg taggtactca tcaagttaaa
    28261 tataaatcag caactcacga ccaaaacttt ttagacagag ctaaagatga aattgatgat
    28321 atgtcaataa atttaaaact tactatacaa aattataaag atatagaaag tcttaagaaa
    28381 aaaatcaatg acaagggtgg gatattgact tggtttgtat gctgttttcc agagaaacca
    28441 aatagttttt taagttctcc ttttgtagaa aatagaataa taggatggta tacttattac
    28501 tttggtcttg atggattttt aagatgggac tataatttat ggacagaaga cccttggaaa
    28561 gattcaagtt acaaattccc tatttggaaa gctggagata tgttctttgt ttatcctgga
    28621 aaagatttaa agccagttag aagtgtcaga atggagaatt taagatttgg aatacaggac
    28681 tttgagttat ttacaatgtt agaaaaagaa aagggaagag agtatataga agttgagctt
    28741 atgcaagaat tattaaataa aaaagaaaat gctgaaatta aaggttttgg tgacatagaa
    28801 ctaggatatt cacttgataa ttggggatat gataaagtta aaaaatatgt attagagttg
    28861 ttagacagag tataaaaaat ataagagtgt ctcaaaatga actttttagt tcatgaggca
    28921 ctctttttgt atgaaatcaa tatagtttca ttgtttcaac aatgaaaaat aggattattt
    28981 ctattctaag acagcccttt agttttttag ttgtattcaa tgttttaaaa ctaactataa
    29041 acgctataaa gtttataaat gacaataatt atatataaca tgatgtactt taatttgcta
    29101 taatagggat tgaataatat tatatggaag ataacattgt ttggggggat taatataaaa
    29161 agaataggta ttattataat gtttttttta agtatatctt ttattggatt ttatcttgta
    29221 ataagagata acagtgatac agttaagatg caacgaggga taaatatagg taatgcacta
    29281 gaatcaccta aggattttcc gtgggatgta aaaatgtcaa ataagttttt tgatgatata
    29341 aaagatgcag gttttgacac agtacgtata ccagtaaggt tttctgatta tacgtcagat
    29401 tctgataatt ttaaaattga tgaagaattt tttaaaaaga ttgataaata tgtagattat
    29461 gcattggata aagacttaat agttgtgttg gatttacacc attttgaaga aattatgaaa
    29521 gaaccaagag ttcataaaga aaagttttta aaaatatggc aacagatagc taataggtat
    29581 caaaaatatg ataaaaaatt ggtatttgaa ttattaaatg aacctaaaga aaatttatat
    29641 tcacagttac taaacgaata cattgaagaa gcaataaaga taattagaaa aactaaccct
    29701 aaaagaacta ttatagtagg accatataat ttctatcaaa ttgattattt gaatgaatta
    29761 aatattccta aagattctaa tatagtagtt tcctttcact attacgagcc aaatgatttt
    29821 gcatttcaag gaaatatcta tcataaggga tttgagcact taagcaatat tacttgggaa
    29881 ggaacaaatg aacaaatgga ttatttaaaa aaaaggtttg atactgtgga aaattgggca
    29941 aataaaaata aggtaaaaat cttcttgggt gaatttggag taacaaaaga agcaccagaa
    30001 acttcaagga gagcttgggt aaaagctgta agagaagaag ctgaaaaacg aaacttttca
    30061 tgggcttatt gggagcttgc ttctggattt ggtatataca atcaaattga agggacttgg
    30121 gatagagaaa tattaagtgc attaatagaa aagaggtgat tttatgaaga aaaattcaaa
    30181 aaagatactt ataactttaa ctattattac taatatagta tatatattgt ggagaatttt
    30241 ttatacagta cctaaagaag aagggatgtt tgccctaatc tgtgccataa tacttctttt
    30301 tgtagagata atgggtatga tggaaatgtt tgtgcattat tatggtatgt caaatattga
    30361 gtaccctgaa aaaccaatca taagtgaaga actttatcca catgtagatg tattcattgc
    30421 aacatataat gaatctgttg atttggtgag aaaaactgta aatgggtgta ttcatatgca
    30481 gtatccagat aagaaaaagg tacatatata catatgtgat gatggaaatc gtgaagaaat
    30541 gtgtattcta gcagaaaaaa tgggtgtaaa ttacataact agaactgaaa gagaaggagc
    30601 aaaagctgga aatttaaata atgcaatgca acatacaaat tcccctttga ttgctacatt
    30661 tgatgcagat atgataccaa tgcatgactt tttaattgct acagtaccat actttttgaa
    30721 aaatgagcaa gctaaaaaag atggagaaaa agaggagtat gaaaaggttg gttttgtgca
    30781 aactccacag agtttttata atccagactt gtttcaattt aatctgcact ctgaaggaag
    30841 gattccaaat gagcaagatt atttttacag agacattcaa ttggctagaa ataggacaaa
    30901 ttctgtaatt tatggtggta gtaatacagt tatttcaagg gaagcacttg aagaagttga
    30961 tggattttat acttattcta ttacagaaga ttttgcaaca ggtatcttaa ttcaaagtaa
    31021 ggggtataga tgttatgcta ttccagaagt acatgcatca ggtttatctc cgacagattt
    31081 aaaaagtctt attaagcaac gtgaaagatg ggcacgtgga tgtatacaaa ctggtagacg
    31141 tctaaatatt ttgtttagga gaggtttagg tttttggcag aaaataagtt atatttcttc
    31201 aattacttat tggtatgcaa gtataaaacg ctttgtatat ataatggcac ctattttatt
    31261 ttctgtgttt aatgtgattg tagtaaaatg tacgttactt caagtattgg tattttggtt
    31321 gccaatgtat attttaagta gtttatctct taaaatattt tctcaaaata taagaaatac
    31381 tagatggacc aatatatatg aaactataat gtttcagtct ttaatgccag cagtaatact
    31441 tgaaacgttt gcaatatcta aaaataaatt ttcagtaaca aataagagta aattagaaga
    31501 aaatagaatg tataagtttt tacagggaat accttatttt atttacatgg tcttatctat
    31561 cataggaatt ttaaaaatgt ttgtagcaat atttaaaatg agttcaatga catattcagt
    31621 tgtattattt tggttgattg gaaacctttt taaccttgtt atggctacat tatttatatc
    31681 agggagacag cagttaagaa agtctgagcg ttatattgct gaaattgatt ttaagttaaa
    31741 gcaaaattct tatgttcttt cttcaaaaac aattgatata tcagaaaatg ggtttgcatt
    31801 tttgctagaa aatccagaat atatttcccc agaagaagag tttgaggtag agtttagaga
    31861 aaaatctgga aatgaaatgt atatagctaa tatgaaagca aagattgtta atgttgtgga
    31921 agtaaattca aagtggaaat atgcagctta tattacacat attgaggata gtgaaataga
    31981 taattggatg tgtattgttc acgatagaat acctacttta ccaatgacaa tatctaatca
    32041 actaggtttc tttgatgatt tgcaaattaa tgtaaaaaaa cgtattgaaa aaactagaac
    32101 attatcacga agaagtccaa gaatcaatat gaattttcag atggatataa aaaatacagg
    32161 taaattaaga atagtgaatt ttaattatca atatgtatta ttaaattttg agaataaaag
    32221 tatttatcct aaagaaatag cattggaaat taatgaaaat attgtgttag aatgtgattt
    32281 gtgtgagggt aaaattgatg aaagaggtat cttatataaa gtaaataaca ttgacagcat
    32341 aatgcaaaat ttctttttaa gagatgaaat gatggattgg atattacaaa ataagacaat
    32401 tcttgtttca aagcctagtg aaaagaagga aaaaagtata gatgagtttg aacccatgga
    32461 atatatttag gagagatgaa atgaagactt taaaagtgtt tttttgttct acaaaatatc
    32521 ttattttggt gtttattttt tttataaata ctacttttat aagttcagca acaagtgata
    32581 aaattttaga tttatccttt aaaaagatag agactgactt aagttctaag attacatatg
    32641 aggatacagg tgtaagaata gaaacggata gttctaaaag cgataaggaa cgttatttat
    32701 atatttacca aaatataaaa gaaaattgga gcatgtataa taatttttat attgaaattc
    32761 aaaataaaaa taaaagttct cagagaataa atttaagcat acaaagtaaa aatatgcttg
    32821 aatttagatt aaaagaaggt agtgaagtat ttttagaagg taaaaatata atatattcag
    32881 ataaaataaa agaaggatgc atagaagtac caggtgaatt tgaaggcaaa atttatgtga
    32941 actttaatag ccttataaat gaggaaagta atgttgtgct ggactcaaat atgctttcaa
    33001 acattgttag ttggggaatt acgtttattc catctgatga agaacataat attgttatta
    33061 taaaaaagat atctttattg tctgaagaga aattaagatt tttaaataat attaaaataa
    33121 ttggcgatga agaagtacaa ataccagtat tgggtcaaag tataagtcag tatgaagtat
    33181 taggtcttaa aagtgattct aaaattaagt actctcttat gggaaaacaa gataatgtga
    33241 gcatatctca aaaaggtaaa ttaacattaa gtaataaagc caaacctgga caaattattt
    33301 tacaagttaa tgttgatgat aagtttaaaa ttggaaagaa aataacatta actgagtctt
    33361 ggagtgttaa taaaaaagat aaggatggtg ttccatatac attagtatat cctgagcaat
    33421 caccaacagt acaagatatg aaaaaaataa actttatgaa taacatcata acgtttgttc
    33481 gaattttatt tgtatctcta gtaataatat gctttggaat atatttatat tggaaaaaat
    33541 gttcaaaaac taagtaaaga gaggaggtta gattgtgtta ttttcaagtt taattttttt
    33601 attttatttt ttacctataa ctttggtttt atattatgta tttaggttta accgaacgat
    33661 acagaacatg atattgcttg ctgttagttt atttttttat gcttggggag agccaaaatt
    33721 tgttgttatc atgatagttt ccataataat gaactatata tttggtttac tggtagatag
    33781 atatagggaa agtaaaataa aagtaaaagt ttttttagtt ttgatgtgtg catacaatat
    33841 aggtgtttta tttatattta aatatctagc ttttgcgcta agaaatatta gtgaacttat
    33901 tagtactgaa ttgactatac ctagtattgt tttacccata ggaatttcat tttttacatt
    33961 tcagggaatg tcttatgtta tagatgtata tcgtagacat ggagaagtcc aaaagaaccc
    34021 tttttatgtg ggattgtata tagcattttt cccacaatta atagcaggtc ctatagttag
    34081 atatgagagt gtggcagaac aaattctcaa tagaaaagaa acttggaata aattttctat
    34141 tggtacttgt aggtttataa caggtctagg taaaaaagta ttaatttcaa ataacatggc
    34201 tatagtagca gactatattt acactatgaa tagtcaagga gaaatagctg catcacttgc
    34261 atggcttggt tcaatagcct atactctgca aatattcttt gatttttctg cttattcaga
    34321 tatggctata ggcttaggtc ttatgtttgg ttttaaattt gaagagaact ttaattatcc
    34381 atatatatca aaatcaatta gtgagttttg gagaagatgg cacatttctt tgggaatgtg
    34441 gtttaagagc tatatatact ttccgcttgg aggttctaga gtagcaaata aagatattat
    34501 gattagaaat atgtttatag tgtggttatt cactggaata tggcatggag cagaatggac
    34561 atttgtaatt tgggggattt taaactttgt tttcctaatt atagagcgat ttataatgtt
    34621 tgaaaagatt gaaaatcaca attttataaa acatatttat gctttattag tagttaattt
    34681 tggatgggta ttgtttaggt cacctaattt aaaagaagca tataattatt ttaaagctat
    34741 gtttggaggc aatggagcta tatggagtga ttatacatat atgtttttaa aagaatactg
    34801 ggttttcttt atatttgcat ttatttttag tgtacctatt gcaaagaaaa tcaataagtt
    34861 tgttgttgaa caagctaaat atagtatgat atttaacgta ttttatccaa tctcagctat
    34921 tttattgttt tttatttctg tgacatattt agtaactgga agctataatc catttattta
    34981 ttttaatttt tagttgggag gaaaagtatg aatagatttt ttaaagtaag attaataact
    35041 gcaattatgt tcttaattat tttattcgct ttctctatct ttaatgtttg ttattctgga
    35101 aaagatacga tacaggaaat aaaaaattca atagctgaaa aaagtagttt aaaagataca
    35161 atatcatcta ttgataatac agtgaatgac aaagtaatat acaaaaatac gttcattgaa
    35221 acttatggct atttacaaaa attaatgggt aaaaatgagt tttcaaaatt tagtgttgta
    35281 aaagatactt ctggaaagat gcattataca tattttgcta aagctccaaa tccagttggt
    35341 gtgatagcag atagggtaag aaaattttct gatgaaatgg aaaagcaaaa cactaaattg
    35401 gtttacctaa tgactccaga taagtatata aaaggagtga caaaatttcc caaaggaata
    35461 ccttattctt atagtaatga gacagcagat aattttttaa atcaactaaa aaagtataat
    35521 gtggactata ttgattttag agaaaatatt ttaaagagtg gtattccaaa agatgattta
    35581 ttttttaaaa cagaccatca ctggaaagta gaaacttctt tttgggcatt tggagaatta
    35641 gttgagcaac ttaataaaaa atacaatatg aatttagatg aaaatcatta ttatagagat
    35701 aaggacaatt ataattcaat tgtatatcct aagtcatttc ttggttctat gggaagaaag
    35761 actggtatct tatatggtgg tatagatgat tttacattaa tttatcctaa atttaagact
    35821 aattatactt attatacaga ttctaaatct caaaaatttg aattaaaagg aaggtttgaa
    35881 gagagtttaa tattatcata tccttttaat gcagacctta atttaatgga tggtcaatca
    35941 gataagtatt ttacatattt attggggaac agaccattag ttaaaataaa aaatatagaa
    36001 aatccagatg gattaaaagt gctgtttgtt aaagattctc taattgtacc aacagcagca
    36061 tttttttcct ctgtttgttc atctatagat atgatagacc ctagatatta tgatggagat
    36121 atactagaat atgcaaaatc ccatgactat gactttgttt ttatatctgt atatccccaa
    36181 aatcttacaa aagaattttt tccgttttgt gagtaaattt ctaaaaaagt tttctgataa
    36241 aataaatggc taactggtaa aaagttagcc atttattttg agtgttattc taagaaatat
    36301 tttttttact aaatacttct ttatctattt ttccaagtga ttttcctaca gtaattgatg
    36361 ataccatagc accattaaca tttatcatag tacgtcccat atctagtata gggtctattg
    36421 caagtatacc accaactaat ggaaaataag aaccaagacc aactccagag ataacaactg
    36481 aaacggccat tgtagcagtt cctggaagac cagctattcc aaacgaacta attgttataa
    36541 caattaacaa cataacataa aagctcatat ccatgtttac tccagccata ttggcaagtg
    36601 ttacagccat taaagcagga tatatacctg cacaaccatt catacccata tttgcaccta
    36661 aacttgctgt aaagcttgat acaccctcat caactccgtg attttgtact agactttcta
    36721 tcgttacagg caatgttcct aaactagaac gtgaagtaaa tgccagaagt aaagcttcag
    36781 ttgaattttt tatataagta atgggattta gaccatttaa agttataaaa attaaatgta
    36841 tgataaataa tattgcaact gatatataaa gagctaatat aaactgtaaa acagatacta
    36901 ttgaactaat accttgtgaa gttattgtat ttgcaagcag agcaaccaca gcataaggca
    36961 taaatttaat aacagtcata gacacactta caattatttt gtaagatgct tctataaaat
    37021 ctataaatgg ttttattgtc tcaaaatgtt ttttacttaa tctctttatt gaggtagcta
    37081 taaatgtagc aaatattatt gtagctacaa tatttccatt tgccatagcc attacaggat
    37141 tagatggtag taatcctctt aaagtatcca caagagagtt tatttcttta agttcttgat
    37201 tttcaactaa agtaggcata ttagctccta cacctaactt cattatattt gcaacgataa
    37261 ttccaacaat tgcagctata gcagtagtag caagaagcat acctaaagat ttaaatgtca
    37321 gagttccaag attgttatct ttcatattta taattacttt tataatggat aagaaaacta
    37381 aaggtactac taacattttt aataagtcca taaatccaga accaaatagg ctataccact
    37441 tacttacttc ttgtagccaa atgacttgag ttgtatcatt agggaaacca gcaaaagctt
    37501 gtattatgat tcccaatatg agtcctagta ctgtagcata tattgttctc aatgaaaatt
    37561 ttattttttt cttttcaaat tgtctaacaa taaagaacgt acctagaagt aatattatga
    37621 aaaaaattgt tttaaaatct gtaatcataa gaaattgtga taaaaatgaa ctttccaata
    37681 tttttctcct tttatttaaa aataaatttt tctaagttta aatgatatca atatattaaa
    37741 aaaatgtcaa tattatatca caatttactt aaatagagta aaacaagttg attttgaaaa
    37801 atgtgattaa gtacagaaaa atagggtata ataaatgttt aaagaatttg aattgtggta
    37861 agaaaataaa aaatagcttt tataagattt gatttcaaat taaaatgtgt taaataaata
    37921 actaaaaatt attataaaaa atgttttcat agaatatata tcaaatgaaa agcttaaaat
    37981 aagtgaagaa attaactaga catcaaagga gagataaaat gagagtaata ataattggtg
    38041 gtgttgcagc tggtatgagt gctgcagcaa aattaaaaag aataaaacct gagtatgaag
    38101 ttgttgttta tgaaaaaact gaaatagtat cttttggtgc ttgtggatta ccatactttg
    38161 ttggtggatt ttttaatgat gctgatgaat tattagcaag aacaccagag aaacttagag
    38221 aagctggaat tgatttaaat atatttagag aagtcgttga ggttgatagt gaatctaaga
    38281 aaataaaagt aaaaaacata aaaacagatg aaatatatga agattactat gataaattga
    38341 tgatagcaac tggagcaaga agtattatgc cttctataaa aaacataaaa ttgaagaatg
    38401 tttctacatt aaaaagttta tatgatggag aatatctaaa aaaactttta agtaatgaag
    38461 ataataaaag agtgacaata ataggagctg gttttatagg gttagaagca gttgaggcat
    38521 gtaagaaatt aggtaaagat gtagatgtaa ttcagttaga agatagaata ttgccacaag
    38581 tatttgataa ggagatgacg gatgtattag aagaagaaat aaatagacat aatgttaatt
    38641 tgcacttaga tgaaatggtt gtagaacttt gtggagaaga taaagtagaa aaagttataa
    38701 caaacaaagg ggaaatagat acagatgtag taataattgc tactggcgtg agacctaata
    38761 ccgagttttt gtcaaatact aatataaaaa tgctaaaaaa tggagctata gtagttgatg
    38821 agtatggaag aacttctgta gaagatatat actctgctgg agattgtgca actataaaga
    38881 atatagtaag taatgaaaat gtatatgttc ctttagctac tggagctaat aaattgggta
    38941 ggatagtagg agaaaaccta gcaggaagag aagtatctta tcaaggttca ctatcttcaa
    39001 gctgtataaa aattatggat atggaggcag catcaactgg aattacagaa aggcaagcta
    39061 aagatttagg cataaatgtc aaatctaaat ttatttctga ttataatcaa actcattatt
    39121 atccaggaag aaataaaata tatgtaaagc ttatttatga tgcagataca aaagttattt
    39181 taggcggaca agtggctggg tttaaggatg ctgtccaaag agcaaatgta ttggcagctg
    39241 ctatctttgg aaaaatgacc acaagtcaac ttggaatgtt agatttatgt tatgctccac
    39301 catttgcaag aacatgggat gttttaaatg tagctggaaa tatatctaaa taatatttag
    39361 attatagcta atatagttga caagcaatta agggaatgaa tttacctaaa ctatttttat
    39421 catggtaaaa ttcattccta aatttttatt ccaaattttt attccaaatt tttagaaata
    39481 aggattccat taaattattc atcaaaattt aaacgcaagc ttaatctatc ttctccaaga
    39541 atagtatttt caaaaacatt agtagcattt tctaaataca tactaggtat gtctaaagaa
    39601 ggactaaaat gagtcagtaa aagttgtttg acatttccaa gttttgcaag attagcagct
    39661 tctctaaaag tcatatgttt gtttctaaca gcttttgata tatctaaatc atcaccatac
    39721 atggcttcac atataaataa atcactatct tttatgaaat ctggtattga ttctataggt
    39781 cttgtatcgg ttgtaagact tatcttaact ccctttctta attctcctaa gaccatatct
    39841 ggagtgtatt gttttgaatc taaaactata ttttgacctt cttggagttt gttccataat
    39901 attttaggaa cttcgttttt agttgcctta tctatatcaa atttagggtt tcttctaaaa
    39961 ttaaaactgt atcctaaaca ctctatagag tgttctaaac tgattgttga aatttctaaa
    40021 tttcttaaaa ctttattatc taaagaaaaa ttgccttgag ggttttctat aatttttaaa
    40081 gtgtatggta catattctac taaatttctc atagaacgta tacaatcgac tattccaact
    40141 ggaccaacta tagttaaatc acttgtacga ccactattcc caattgttga taaaagtcct
    40201 aaaagtccaa atatatggtc accatgtaaa tgggttatac aaatcaagtc tatatcttta
    40261 aagccacatt tttttagctt catagatacc tgagtacctt caccacagtc aattagtatt
    40321 tttctacctt tatagtttat aaatacagag gatagaaatc tgtttggcat aggtacattt
    40381 ccaccacatc caagtaaagt taaatctatc attttttccc ctttctaaaa ttaacacaaa
    40441 tctgttgttt gtttttatta tgatatccta ttataattat tttaacatta aatataacaa
    40501 taaatgtgta tttgagtcaa gaaatattgt caaataaagt ttttatataa caatgtataa
    40561 aaatttggag gacaaaaagt gaaaattata tttagaagta tttaaaggag gaaaatttaa
    40621 tgaaagtatt aaagaaaatt actattttgt tattgattac attaacttta gttggttgta
    40681 gtaacggaga agagaaaaaa gtggttgaag gttctaagaa aactcaaaat tctaaaaaag
    40741 atgaacagcc tataatagtg cataaagatg caaatatatt gaaagatagg tatgagccac
    40801 caaaaggatt taaaagagtt gatgtagaaa aaggtagttt tgaatcattt cttaggaata
    40861 ctaagctaaa aaattatgga gagaaagtaa agtattatga tggaagaact aaggaatcaa
    40921 aaggtattta tgatagtgta tttgatgttg atattggaaa tagagattta catcaatgtg
    40981 cagatgcaat tatgcttatg agagcagaat acttgtatca gaataaacta tatgatgaaa
    41041 taagttttga ttttgttgat ggttttaagg cgaagtattc aaaatgggca caaggatata
    41101 gaatttcagt aaaagatagt ggttcaagct ggtataaagc aactgaatat tcaacatctt
    41161 atgagagttt cagaaagttt atggatatag tgtttgcata ttcaggaacg ttatctcttg
    41221 aaaaagaatt ggagcctgta aaagttgagg atatgaaaat aggagatgtg tttatagttg
    41281 gtggaagtcc aggacatgca agtataatta tggatatggc agaaaatgaa aagactggtg
    41341 aaaaggtatt tatgatagcc caaagctata tgcctgcaca acaaacgcaa cttcttatta
    41401 atcgtaaaaa tccaaatttg agtccttggt atagtttaga ttttgaaggt gatttgacaa
    41461 tacctcaatg gacttttaaa agagaccagt tgaaaagatt ttaaaataat aattttatat
    41521 aataaaagaa aaatatagat gtgaaaaaat gtaattagat taaaactaat tggatatgga
    41581 caaaattaaa ttgatagata aatattaaaa attacactaa ttaatcttac tatagtttaa
    41641 tatttatcta aaaagtttta tgtaaaatat aaattttata ttaaagctaa aactaatttg
    41701 aggaggctaa tttatattga agattagaag gtatttaatt ttggtaatta taattctaat
    41761 tacaacaagt cagagtttta tttcttatgg gctagagcga tttgaagaaa taaccatttt
    41821 tcacactaat gatatacatg gaagatatgc tgaaggtgat gaccatatac aaataggaaa
    41881 tctagccaca ttgaaaaaag aaactccaaa ctcaatttta gtagatgcag gagattgttt
    41941 gcatggactt ccaatagtaa atatggatag agggaaaagt gcaattgaat taattaaatg
    42001 tgctggatat gactatatta ctcctggaaa tcatgacttt aattatggaa aagatagact
    42061 gtttgagtta tctaaaagtg ctaatttagg agagaatact ttaaaatttt tatcatcaaa
    42121 tatttttgaa aatggaaaaa aagtttttga tagtaatgat ataaaagaaa tagatggaat
    42181 aaaaatagga ttttttggac tctcaaccca ggaaacaaag agcaaaactg gatttaaaaa
    42241 tgtggaagga ttagagttta aaaatcctat agaaagtgca acagaacaag taaatgaatt
    42301 aaaaggaaag ggtgccaatg taatagttgc aatatgtcat attggtacaa atagtttaag
    42361 taagccaaat agtatagata tagcaaatga ggttcaagga attgatttga ttattgatgg
    42421 acacagccac actaagtttg aaaatggtaa acaagtgggt gatacattga ttgtaagtgc
    42481 aggacaatat ttagaaaata ttggcgagat aaaactaact ttggatacta atgatgtaga
    42541 aaatataaaa atagaaaata aatcagttag attaattgga aaagaagaag cattaaagta
    42601 taagcttgac tccgctgtaa gtaaaaaggt tgatgaaata aaagaacaac aagaaaaaat
    42661 attagataaa gttatagggg taactacaaa tactctagat ggttcatatg aaaatgtaag
    42721 gacaaaagaa actaatttgg gtaatttaat aagtgacatt ttactagata aaactaaggc
    42781 tgatatttct ttatttaatg gagggaatat tcgagatacg atagaaaaag gcaatataac
    42841 aagaagagat attgtagatg tatttccttt tagcaatact atagttacca aagaacttac
    42901 aggagcacag attaaagatg tattggagca tggagtaaaa ctttatccag aaaaaagttc
    42961 agcctttttg caagtgggag gaatttcata ttactttaat cctaaacaaa aagaaggcga
    43021 aaaaataaca aatattcaaa aagaaggaaa gccattagat ttaaataaaa agtatgtagt
    43081 tgcaacgaat gattatatag catcaggtgg agatgaattt ccttgttttt caaaagagcc
    43141 agtactaaag gaatttggaa atttagagag tgcagtcatt gaatatatag agtacaaaaa
    43201 agaaatatca aaaaatgtag atggaagaat tggtattaaa tctaaagatg agttaataag
    43261 caagaatcat gagagtgatt tgatattaag tgaaaatgaa aaaaatatca atgataatga
    43321 agagaatcta tctaataata taaaaagctc tgatagtgat aaaaataaaa gcttagataa
    43381 aacaagtgct agagaaagtt ctaatctagg aatatctaaa agagaagcta aagaaaaatc
    43441 tcctaaaaca ggagatttag gtttttcaaa tagtataatt atatttatag tttcaagtac
    43501 attgatatgt ttattgaatt ttaatcaaaa agagttaaag gataaaaagt caaaataaaa
    43561 attaatgagc aaaaattagt agatagtaat ttaattttag ataatagtaa acagcaaagg
    43621 aaattagtta tataaatact aatttccttt gttttatgtt ttaacatgat tacttttaaa
    43681 taaaattgta ttttatgaaa aataattaca ctaaatggca tagtattatg gggattttta
    43741 gtttttattc aagtaaatga aatcatatta acaacttctg atatatttac aaattgataa
    43801 aaaaatgatt ttattagtat gatataattt agctagtata tatgatgatg gaggatatag
    43861 ggatgaataa tatattactt ttggaagatg acaaatcttt aaatagagga attagtttta
    43921 aattaaaaaa agaaggatac aatgttttta gtgcatttgg tatagaagaa gcaaaaaata
    43981 ttttcgcaaa agaagagata tgcttaatta tttccgatat aggtctacct gatggtagtg
    44041 gttttgactt ttgtgaggag attagaaaga aaagtgatgt ttacataata atgttgacag
    44101 ctcttgatga agaggtggat attgtcacag gatatgattt aggtgcagat gattatatca
    44161 caaagccttt tagcttgatg gtattaatat caaaagtgaa tgcgcttatg aaaagagtaa
    44221 atacagtaaa aaattatact ctattagttt gtgatgattt attcttttat tatatagaaa
    44281 ataaattaat tataagaaca gatgataagg aagaagagat aattttaagt aagacagaga
    44341 caaaactatt aaaatatttg atggaaaatt ctatgcagac attgactaaa gagcaactgt
    44401 tagaatcttt atgggatagt agtggtaatt ttgtagatga taatacgatt gcagtaaata
    44461 taagaagact tagacaaaag gttgaaaaaa atccatctga acctaaatat ataaaaacag
    44521 taagaggggt tggatatatg tggggagaaa ggagtataaa aaaatgctaa aaaatatgaa
    44581 cctcaaagat ggtttaagtg tgaaagatga ttatataatg agaagagtta ttgtatattc
    44641 tgttttatct gtactaatag taacccttgt atttatactt tttgaatata gcagattaca
    44701 taaattgtat gaacatcaaa taaaaaatac tcaaaatatt gctggaatat tgattgaaaa
    44761 atatcctaat gatgaaatag atatagtaaa ttctatttat aattctgatt atagtaaggt
    44821 gtctactgga gaaaaggcat ttaagaaatt tggctatgga ttggaaaata aaatgtcaaa
    44881 tgataaaaat tttagcttat acttaaaatc tttttttaag gaatcatttt ttattttttt
    44941 aatgatgttt atagtagtta taggtataat atattatttt ataagataca taaataaaag
    45001 attgagtaaa atttatttta tagtagataa gatgtcacaa gaaaactact tgaaggacac
    45061 tactgagtca gaagaaactg gttatctagt agaatataat gaatacttta aagaaggcat
    45121 atttagtaag ataaataact gtctatatga gcttaataga agtttaaaga taaagtttat
    45181 taaattagaa aaagaaaaag aaagtgtaaa atcattagta acagatattt cccatcaatt
    45241 aaaaactcct ttagcatcct taaaattata caatacatta cttatagaag aagaattaga
    45301 agaagatgaa gccaacgagt tcttattaac caataaggct tctataaata aattagaaaa
    45361 tttaataaat tctttagtga acatatcaag gttagaaatt agcatgataa acataaaaaa
    45421 agaagataat gatataaaaa atactattct aaatgcagta aaaagtgtta cccctaaggc
    45481 taagagcaaa agtataacat taaatttaaa tgaatttaac agtagaatta taccacatga
    45541 taaaaagtgg actgaggaga gtatttttaa tgtattagac aatgctgtaa agtatacaca
    45601 ggtaaatgga gaaataaata tatctgtaga agaaactgct aatttcttta aaattataat
    45661 agaggataat ggcataggga ttgaaaaaaa tgagtttaat aatatattta aacgttttta
    45721 tagaggttct gctgatgaaa ttgaatctgt agaaggtagt ggggtaggat tgtatttaag
    45781 tagaaagatt ttagaagaac aaggtggaaa tattatagtt tcttcaaaag taggaatagg
    45841 gagcaagttt tctttgtttc ttacaactat gtaatattaa atgaaaggaa aatgtaagcc
    45901 tctacattta ttatataagt ataaacagct ccagaaataa aaaattaata aaatatggag
    45961 taatataact tagaatgaga ggataatttt atgaaaatac tatatactga aaatttatca
    46021 aagcattatg gaaaaggaga aagcttagta agagctttgg acaatgttga cttagaaata
    46081 aatgaaggtg aatttgttgc aataatagga aaatcaggtt ctggaaaaag tacacttttg
    46141 catatgattg gaggtcttga tatacctaca tctgggaagg tgtatataga taataaaaat
    46201 atatttacat taaaagaaga agaacttgct gtatttagaa gaagaaaaat agggtttata
    46261 tttcaaagct ataatttaat tccatctctt aatgtatggg aaaatgtagt gttgccaatc
    46321 ggtttagatg gtagagaagt agatgaatct tttataaaag aacttttaaa atcattagga
    46381 cttgaaaata aacacgacgt tttaccaaat acattatcag gtggtcaaca acaaagggtg
    46441 gcaatagcaa gagcattagc tacaagacca gctataatac ttgctgatga accaactgga
    46501 aacctagatt ctaaaacgtc tgatgaggtt atgagtatat taaaatctat gtctaagaag
    46561 tacagtcaaa ctctagttat gataactcat gatgacagta tagcccaaat ggctgataga
    46621 gttatattca tagaagatgg cagggtgtca aaggttggtg ataaaaatga ttaatactac
    46681 taaaatagca aaaagtaatt taaagcaaaa taaatcaaaa agtattctaa taataattac
    46741 tataatactt tcaaccttaa tgctttcttc tattggaatt tatattgttg atgcaggagc
    46801 atatcaaaaa gaaaacacta taaagtattc aggtaattat caaggtatat tagcaaatgt
    46861 agatgaaaaa caggctgata tattgagtaa tcatgcagat gttgaattaa ctggtgaaat
    46921 gaatggagta ggtgttgaaa aactggaaga tgattcaaat atttctctag catacatgaa
    46981 tgaagatgct ttgaaattaa atagttttga atttatcaaa ggaaaattgc catcaaaaga
    47041 gaatgaaatt gtgttagata gtggagcttt aaaggcactt ggttataaaa ataaagattt
    47101 aggtgaaaag ataaaaatat cttatgatga ctataaaaat gataaaaaaa ttgaaaaaga
    47161 gttcattata agtggaatct taaaaactag cgaaatatct gaagcaggta aatattatta
    47221 tgctattata tcagaatcat atatgagaaa tactagagat atgtcacaag aagattttaa
    47281 tatttatgtg aaatttaatg ataaaagtaa tttatcaata gagcaagcaa aagaaaaatt
    47341 agataaaatt gctaatgata taggactgga tactattaat actgctgtaa atgaaaatta
    47401 tataaatgct ttaaaaccag atatggaaac gattatgggt ggagtttttg tagggttagt
    47461 aattgtatta tctagtattt tagtaatata caatatattt tatatttcaa tagttacaaa
    47521 ggttcaagaa tttggaaaac ttagagcaat tggtgcaact aagaaacaaa taaaaaatat
    47581 agtgtttaaa gaagggttca tattagccgg aatagcaata ccaataggaa taattttagg
    47641 ctatgtactt gcaaatatta taataaaatc atttatggat atagatgtaa aatcatcacg
    47701 attaccagtt atattatcgg ttgtggtaat aagctttata tctgttgttt tatcactttt
    47761 aaaaccaatg aaagtagcat caaaagtatc cattgttgac gcagtaagat atacaggaaa
    47821 taaaataagt aataagagta agagaaaagg atataaaaat ataaatctaa agagattatc
    47881 acatgccaat ttagaaagaa ataaaaaacg tacttacatg acattggcat cacttatact
    47941 tagtggaact atatttataa cagtatcaac tgccttagaa agttttgatg ctgagaaaat
    48001 ggcaagagaa cactttcctt atgatataga agttagacta tctggttatg aaatgaacag
    48061 tgataaaaat cctaaagata atttgaatat tttacaaatg gataatcctc taagtaaaga
    48121 tttttttaat caaataaaga acatggaagg aattaaaaga atagaatctg caagaagtgt
    48181 aaaaattggt atggaggact atgatgttga atttaagtat gaccttttac aaagtataaa
    48241 tgaaaatgat gtaaaatcat taaacaagaa tataatagat ggaaaaataa atcttgaaag
    48301 acttcaaact ggagatgaaa tagtaattac tcatgttgat acagcaaaag aaatgggagt
    48361 aaaagcagga gataaaataa gattaacttt atatgatgga gataaaaaga taaaaaaaga
    48421 atttaaagtt caagcaatag ctatgggggt tccaagtttt ggtataggga aagattttat
    48481 agatagaact ttgaaatacg attcaactag tagcttggga atatatacag aagaaggaaa
    48541 gtatcaagaa atcaaagata gtatcaagaa gattgctaaa aataatggat ttttagagac
    48601 tgactttata gatagtagaa ttgagtcaaa taaggctact atttcattta taaagataat
    48661 gggatatacg ctaacaggca taataggtgt gattggattt atgaatcttg tcaacacaat
    48721 gataactagc atagttacta gaaaaaaaga acttggtatg cttcaagcta ttggtcttac
    48781 taataaacaa ttagtgaaaa tgcttaattc agaggcaatg tattacactt ctggaatgat
    48841 gataggaagt attctatttg gaggtatatt agggtatatt gctgttatat ttctaaaaaa
    48901 gactggatta tcttatgcaa catattcttt gccaatagta ccaatcttgt tgatgattgt
    48961 gtgtattctt atagctcaat ttataacaac ttatttgata ggacgaagtt ttaataaaga
    49021 atctcttatt gatagagtaa gatacagtga ataaaatgca aatatttatg gttagtttaa
    49081 ctagcaaaaa acatataaaa aaatatagtt aaagaaattc ataattaaat aggttaaagc
    49141 atagtacaga gcaaacaatt taaacagatg tttgctctgt attttattat gtaatcaata
    49201 atatatctaa tatactgata ttattcatgt tagaaaatgt accggtacaa ttctaaaaaa
    49261 gtataaaatt gtaccatata aaatgaaaat tttgtataat aatcgtatag aaaataaata
    49321 ggagctgata tatatgaata agaagattaa ttatgcacca ggaccaactg aaactaggga
    49381 aaatgtaaga ttagcaagag cagaaaaaac aacaaatcca gatatagata ttgattttgt
    49441 tgaattttat aaaaagacat gcgagaagtt tggtaatata attggaacaa aaaacgatgt
    49501 ttacatattg agtggtgaag gaatattagg tcttgaagca gcatgtgcat cacttacaga
    49561 aaaaggagat agagtacttg taattgataa tggtatatat ggagaaggtt ttaaagattt
    49621 tgtaacaatg tatggtgggg agtatgtgct tttttcaagt gaatatacta aaagtataga
    49681 tattgatgaa ttgaaagcat ttttagatga ggatagtaat tttaaatatg caacagtagt
    49741 gcattgtgat actccaactg gcgtattaaa tgatgtaagc aaaatatgtc cattacttaa
    49801 aaaatatgga atattaactg tagttgattc tgtagcaggt atggtaggag aaagattaag
    49861 tgtagatgaa tctaaaatag atataatatt aggtggttca caaaaagcta tttctgcacc
    49921 agcaggactt actatagtcg gaataagtca agatgcaaaa aattgtataa aaaatagaaa
    49981 aactgatgta ataggttttt attgtaattt aaatatatgg gaaggctatt atgaaaaaaa
    50041 atacttccct tatacaatgc caataagtga cataatgggg cttgataaag cacttgataa
    50101 tatattagaa gaaggaatag aaaatgtatt aaatagacat gaaaagatag cttatagtgt
    50161 tagaaaatct attgaggaat atggtctaga actattttta gaagaaggat attctaatac
    50221 agtcacagct ataaaagttc ctgaaagtat aggagcttta gaacttactg attatatgct
    50281 taaaaattat aatacacttg ttgcaacatc actaaatcaa tatatggata ctattttaag
    50341 aataggtcat atgggagaga atgcaaatct aaataaaata gaacatgtac taaatgtttt
    50401 ggataaaagt ttaagtgcac taggattcaa aggaaatgga aatttgttaa atttatttaa
    50461 taagtattat ttttaataga tagggggata tagtatggaa gttacagcta agcaaaaatt
    50521 tacaacgaaa gacatggtgg aaacctcact attaatagca ttagtattta ttgcaactaa
    50581 atttataaac ataagattac caatatctat aaatggtggg cttgtgcatt taggaactgc
    50641 aatgttgttc atatcagcaa taatatttgg aggtaaaaaa ggtgctttat caggggctat
    50701 tggtatgtca ctttttgatt tgatatctgg gtggacttta tgggcaccgt ttacctttat
    50761 agttagagga gttatgggtt atttacttgg aaagattgca tgggcaaatg gtaataatgg
    50821 gaataatttt ttaatcaatg taataggaat atgtgtctca tcaatttgga tgctatttgg
    50881 atattatgta acagaagtta tactttatgg taattttata gtacctctta cttcaatacc
    50941 aggtaattta atgcaagtat tgataggtct tataatagcg cttcctattt ctaaggtatt
    51001 gaaaaactgt ataaaataaa tataaagtga actaaaattt atgatagcat aaattatact
    51061 gtataatatt aggatggagt acataattaa aaaattttag tatagaggtt agttcacaat
    51121 gttatcagtt acaagatatt caatcaaaaa tgttcgttta aagccgtggg taaagtttat
    51181 ttggtatttt gagacaaaat caaatatact gttaaataat aagttacttc cgacagacag
    51241 tatagatatt attctcaatc tttctgatgt tatggaatat aaaattgaaa atcaagacta
    51301 tactgctagt aatatgcatt ttaatggaat aagggataaa catggattta ttattcaaca
    51361 tggaaatata cgtgttatag ggatttcttt ttatccattt ggtttatatc catttttaaa
    51421 gataccaatt tcagagttta acagacaaat tgttgactta gaagtagtat cacagctatt
    51481 tgcaaaaaaa ttggaagagt cattaagtcc aacacaatca gtagaaaaaa ttgttttata
    51541 tttagaagaa gtattattat ccatattaga agaagattta atttcaaata aatatgtaaa
    51601 gcttctaaat tcatttatat atgttaatag atatagcaat ataaaggcat tttgtgatga
    51661 tacaaatata aatattaaaa cattggaaag aatctgttta aaatatacag ggtatacacc
    51721 taagatttta aagagaattt acagatttaa aatggcaagt aatcaactta tttataatta
    51781 taaagatgat gaactttttg attttattta tgaaaatgag tactatgacc aagcacactt
    51841 tataaaagaa tttaaaaaat tttcagggac gtcaccaatt aaatttattg gtgagaataa
    51901 gacgattaaa gaaaatataa agtacagcta tttataatta tactgtcgat tttttacaat
    51961 acctccaatt tattttttga tatgatatag gaaaataaat tggaggtttt acatatgaaa
    52021 attattacag aaatagttga gtttaatgtg gaagaaaatt tatcaaaaga agagtttata
    52081 gaaattgtaa atgacttaga attaaaattt cattctattc aatctggttt tattgatact
    52141 gagcttttat atgatgaaaa gtctcaaaag tggattatga tacaacattg ggaatctata
    52201 gaagacctca agagtgcttc tagtaaaatg tttaaagatt cttcaactga gaaatttaga
    52261 aaagctttaa agaatcaaac tgttaagatg aatataatac cacaaattaa aagttggaaa
    52321 ttatagaact gaatgtaaaa gatagttaaa tagtatcaaa ctaaattagc caaataacat
    52381 tttgtattta aattgttatt tggcttttag tgtttatttt aatatgagtg ttatatacta
    52441 gaaaaaccaa caaactgtta gagtgtggat tatcataatg tcatattcgg gagctaaaag
    52501 tcttaatact gatttgccaa ttggtcaatc catgcatgtc catctggata tgctgttatt
    52561 aaagcattta caagccaatc cctttgctct tgtgataata gtgggactgt tacatcgaag
    52621 tctttttgat aaccaagcct atctatgtat attgatttgc aaaacaaaac cacttcggga
    52681 gccatatatg ggatattatc tgatgttatc agtctggcct tatccatatc tcttataatt
    52741 ctttgatttt gggaaaaaag aaattttcca tctttctgtg gattatgtat caattcaata
    52801 aaatcgaact gtaactgttc gtcacactgt atattcattt tatagttatc atcctcgact
    52861 ttttttaatt caataaatga gcaatcaggc ttaatcgcaa aaacacaaat ttgctctata
    52921 tgttgcttgt taaggtcgat aataggtcgt aataaataat tacccaaggg ctcatatata
    52981 tcccatcctt gattaagcat atactgaatg ctcttttctt tatctgtgtc agaaatccat
    53041 atgtcaatat cactgtgtgg gcgaatatgc atattcgcaa ataattctag ggcatatcca
    53101 ccacatattg aatatgaaaa gccacaatca ttaaaaaagt ttacacaatc tttaattagt
    53161 ttgttcatag caacctcctt ttgcatgtac tgaaataaat taaattttta aaaataccaa
    53221 ctaaatgttt gttttgtgta aatataaaac tgccgatatt aaggcagttt tatatttact
    53281 atttagaaaa tttattaaca aatttttgat attcacacat tatcttatca ttcataaaag
    53341 aaatacccat aaaagcagct tgctcaccaa acaaagtaaa acgttctatc atctgttgtg
    53401 gattacctgg ataaactgtt ggaatacacc atgtgtttag aagaaaacca aacatttgag
    53461 cagcaatctc tggattttta acttccatag aattatcttg atttccttct tcaatcaatg
    53521 cttttatcca aggcacaata tcatttataa tctcatcaaa ctgcgtagct aaatacttag
    53581 gattacgcaa tagtgatgat gacattaaaa aaatgtcttg tttattgtgt tgttcataag
    53641 catgaagcaa cctatattgt aatttttcta atgcggtctt tccttcatca ttttttacct
    53701 catacccata aaatccatca ttatacaacc gacttgtgat tgccttaatt atttcgtctt
    53761 ttgatttaaa gtgatgataa atagcacctc ttgaaaggcc atctaaatta tctacaatgt
    53821 cttgaatcgt tgtctgctca tacccttttt ctaagaataa cttatgtgaa atatcaagta
    53881 ttttttgtat agtattatca ggttcttttt ttcttcccaa aaagctcact cctcaaaaca
    53941 atcatttggt atgtttatct tagcaaatac ataatgattt gtcaatgtgt ctttttagca
    54001 tgttgaacag gtatattgcc atgctttcat tattttattt ttttgcctta tactggacta
    54061 tatttgcagt ttcctaatat atttggctca tatttaaata ccattatcta aaagcactat
    54121 tgctgtacga gaggcaatag gcattttaga agaaggagga gttgagttaa agtatacatc
    54181 ataatctctt aagttttctt tttttgtgtt tcctccaaac tctaccatat cagtatttaa
    54241 tatcgttttg tagtttgtat tttgaaactt tgaaatatca actgattgta ttagattagg
    54301 gtggaaatta aatataaata aatatttgcc cttactgtac accaaaatct ttttatcatt
    54361 atccatatgt ataagttcat gactattttg gataaaaata tcactgtatt ttgtaagttc
    54421 gagcatagat ttatcaaaat ttaataattg tttatacttt aagttgttat cttctgaaag
    54481 gctccattgt cttctggcat acttatagct ccaattgttg ccttctcgtg gaaaatcaat
    54541 ccactcagga tgtccaaatt catttcccat aaaatttaga tatccttcac ctgctagaga
    54601 aaaagttatt aatttaatta atttaataag agatattgct ctattgataa catggttatt
    54661 tgagtttatt tccatattcc agtacatttc cttgtcagct agccaaaaaa taattgtttt
    54721 atcgccaact aatgcttggt catgggattc acaatatcct atattttttt ctccaggtcg
    54781 tctagtagta agttcatacc acatttttcc caaatcccag tcttcatcag ataagttaga
    54841 gatagttttt atccaaaaat caggtactcc cattgcaagt ctatagtcaa atccaattcc
    54901 gccgtctttt atagggatac acataccagg cattccactc atatcttctg caatacttat
    54961 cgaattaggt ttaatttctt ttattaattc atttgcaaat tggagatatg ttatagcttc
    55021 aatatctgta ttcatactaa aatatttttc ataactatca aatgaaactc caagaccatg
    55081 gttatgatat aacattgaag ttacaccatc aaacctaaag ccatcaaaat ggtactcatt
    55141 taaccaaaat tttatatttg aaagcaaaaa atgtattact tcaggtttac catagttaaa
    55201 aagttttgta ccccaagcag gatgatttcc ctttgaacct gagtggaaaa attgatgttc
    55261 acttccatca aactcattta ttccttctaa agtattcttt acagcatgag aatgaactaa
    55321 atctaataaa acagcaatcc ccattgaatg agcagtgttt atgaggtttt ttaagtcttc
    55381 aggagtacca aacctagatg agattgcata aaagtttgaa acttggtatc caaaagatgc
    55441 ataatatgga tgttccataa tagccataag ctgaatggta ttgtatccag ctttttttat
    55501 cttaggaagt attttttcag taaattcatt ataagttcca atagattcgc tttcagtaga
    55561 catacctata tgacattcat agattagtgg agaagttatg ttttttaagt caaaattatt
    55621 gtcagtccag ataaatggag tttttggttg ccatatttgt ccattaaatc caccaaaatc
    55681 tttttgaatt actcttttta tatataatgg tatacggtca aatgtttttc catttgcagt
    55741 aacttgtacc tttacctctg atttgtgagg taagctattt tgaccaggaa taaatatttc
    55801 ccaattacca gacccaattt ttcttagagg atgagatttt ctattccaat tattaaagtc
    55861 accaattagt gacaaactat ctgcatttgg agcccattcc ctatagaaga atccatcatt
    55921 tgtctgatga aatccatagt aaagatgagc atttgcaaaa gaactaaaat ctttatagtt
    55981 tttcaatgtt tttgatttca tatcctcata atgtttcatt cgctttttta tatcagattc
    56041 aaatggttgt aggtatacat caatatctaa aattttaaat cttttttgac ttttcattgt
    56101 atttctcctc cataataaat attacatcta aaaaataata tttatctcat actatcttct
    56161 ctgtataatt gatatatatt atataatcct aataaaaagc ttaagccacc aatgattaat
    56221 ttcataattt acctccctag tatttatact tatatatcgt attcatcaaa atttaaaagt
    56281 ttgtttaaaa ctcttttaat aatatcataa tcaaagcctt tataggaaag atgttgagaa
    56341 attttttgat atattttctt tttatcttct ttctttactc tttcatacct tttttttgct
    56401 agatacatag cattttcaaa ttcagtgtcc ttgtctaatt cagatactgc ttcattgatt
    56461 gtacttctat tgataccttt attatataaa ttctgcttaa ttctgttttt gccacattta
    56521 tttaggttaa catttgtgtt aacaattttt tgagctaata cactgtcatt tacgagatta
    56581 taacttttaa gaaaatctat gaccctctca attatatttt catcaaattc tgatgatagt
    56641 ttttctttta attttttttc agattggtca gcatgagata aaatatttaa tgctttattt
    56701 ttagctttta tatacatttc atcatctaaa ataggtttta attcttcttc atttatttca
    56761 ttcccctttt ttaaattaaa tgtataaaca agttctttaa atatagcaat aaaaaattta
    56821 tcatctacat aaatattaac tctatcatca tttctttttt gttgttctat ttttgtaatt
    56881 atacccataa gtcctccttt tttatatgta attatattaa caaaagcaac taataaaatt
    56941 taacaaaaaa cttatatttg tatgttatat tttatcaaaa ttaagacaaa atagtaaaaa
    57001 gttattttta ttaaaaagta aagtagaatc atgttaaata attatttttt taagtgtttt
    57061 ttagcatata aatataatta tatacccaaa aaaacaaatt ataagcttta agaaataaaa
    57121 aataatggta caatagtatt ataacattaa aaggagacaa aatatgagaa gtgaaaatct
    57181 agttaagatg gcagagttga aaaatactga aaaactagag aaatttaatc gccataaagg
    57241 caaaatcaaa ataggtatat tgggaggtac ttttgaccct atacactatg ctcatttagc
    57301 aacagcagaa tttattagag ataagtatga cattgacaaa ataatcttta taccatcagg
    57361 aaatccacca cataaattat gtatcactac agataagtat gatagatata atatgacact
    57421 tctagcaact gaaagcaacg aagatttttt agtttcaaaa gtagaaatcg aaagaaagaa
    57481 aaggacttat acaatagata cattaaaata cttaaagaaa aaatacaaaa atgcagacat
    57541 ttattttata acaggtgcag atgcaatttg tagtgttgaa gagtggaaag atgtaaagaa
    57601 aaactttgag ttagctactt ttatagccgc aactagacca ggaattagtt tgttaaggtc
    57661 acaagagact atagaaaaac taactaagaa gtataatgct gacattataa cagtttatgt
    57721 tccatcactg gatatatcgt ccacatatat aagggaacag ctaaatgaag gcaagtcaat
    57781 acgttactta gtacccgaaa atgtagaaaa ttatttatat gaaaataaac tatatcaata
    57841 tggagatgat taaatgaact tagaaaatat taaccaaaga ctaaatcaaa tgctaccagt
    57901 ggggaggctt agccattcaa aaaatgttgc aaaatgtgct gaaaaattat gtgagattta
    57961 tggatgtgac aaagaaaaag cttacttagc aggaatgatt catgattgtg caaagtattt
    58021 aagtgacaag gaaatagagg attatgtaaa taagtatgaa atatatttag acccaataga
    58081 ggatggaaat cgttccttgt ctcatagtgt aattggggcg tacatatgcg agtatgaatt
    58141 tgaagtagaa gatgaagata ttataaatgc aatcaaatat catacaacag ggagagagga
    58201 catgtctctt ttagaaaaaa taatttacat agctgattta attgaagaag gaagaaaatt
    58261 cccagttgta gatacattaa gagaattagc atatggaggg aagcttgatg aagcactttt
    58321 aacttctttt aataatactt taatgtttgt catcaataaa aaagaagaga tacatccaag
    58381 aacagttatg gcaagaaact atctaattaa agaaaagtta ttataaaaaa gctatataaa
    58441 ggcaaacata ttaataaatt taaatttgac tatgttacaa aatcgtatta atatgttaca
    58501 ataactaagt gtattttaat taggaaagtg aggaattttt atatgacagt ggaacaaatg
    58561 acaaaaatag catatgatgc catagaagat aaactgggtc aagatacagt tataataaat
    58621 ataggaaaag tttctagttt gtgtgattat tttattatta ctacagcatc ttctcagaga
    58681 caggtaaaag ctattgctga caatgtggaa gatgaattag caaaactagg attagagcca
    58741 agaggtaaag aaggacaagg aactcaaact tgggtactcc ttgattatgg agacataatg
    58801 gttcatgtat ttaatgagga aaatagaggg ttttataatt tagaaaaatt atggaaagat
    58861 gcaccttata tagatattga cacattagca taaacatgat aatatatgtt attataatta
    58921 gaaaatttca aaaattatat taaattgaat agactagagc agtaaaagat tatatttttt
    58981 cagagagtta gtggaaggtg agaactaata ttatataact ttgaacttac tagattaaaa
    59041 tctattctcc atggctggat taaaagctat ctaagagagt ctatatatgt agtaggctaa
    59101 ttagggtggt accgcgaaga tttatcctcg tccctaaacg taagtttagt gacgaggatt
    59161 ttttattttc aaagaattat ttggaaatta taagtaaata atactaaata aggtagttat
    59221 acacaattaa aaataggagg caaaatatga gcgtatataa ttttaaagaa gtagaatcga
    59281 aatggcaaaa aatctggaaa gataataatc agtataaaat ggatactgca caaactgaaa
    59341 aacctaatta ttacacatta gaaatgttcc cttatccatc tggaaaaata cacatgggac
    59401 atgttagaaa ttattctata ggtgatgttg tcgcaagatt caaaaaaatg gaaggatata
    59461 atgtacttca tccaatggga tgggattctt ttggattacc agctgaaaat gcagctataa
    59521 aacatggaat acatccgcat aaatggacaa tggaaaatat agaagaaatg aaagagcaat
    59581 taaatttatt agggattagt tatgattggg ataaagaagt tgcaacttca actccagaat
    59641 actatagatt tacacaagaa atatttttga agtttttaga gcatgggctt gcatataaga
    59701 aaaaatcata tgttaactgg tgtccttctt gtgagactgt tcttgcaaat gagcaagttg
    59761 ttcaaggagc atgtgagaga tgtaaagcaa cagtattaaa gaaagattta gaacaatggt
    59821 attttaagac tactgaattt gcagaagaat tacttaatga cttagataca ttagatggat
    59881 ggccagaaaa agttaaaaca atgcaaaaaa attggatagg taaaagtaca ggagcagatt
    59941 tagtttttga tatagatgga actgataaat ctatgacagt atttacaact agaccagaca
    60001 caacttatgg agttacttat atggtacttg ctccagagca tgaattagtt aaagaattgg
    60061 ttgcagggac tgaatatgaa gcagatgttg aaacttttgt tcaaaaaatg catactatga
    60121 cagaaataga aagaacagca gctgatgtag aaaaagaagg aatgtttata ggtagatatg
    60181 ttataaatcc tttaaatggc aagaaagttc ctctatggat agctaactat gtattagttg
    60241 agtatggaac gggtgctata atggcagttc cagcacatga tgaaagagat agagattttg
    60301 ctgaaaaata taatttagac ataattgatg taataacaga agataacaaa atgataaatt
    60361 cagaagaatt taatggatta gatgcttcag aaggatttga aggaataatc gataagttag
    60421 aaaaagaagg tagaggaaag agaacaatta attatagact tagagactgg ttagtttcaa
    60481 gacaaagata ctggggttgt cctatacctg tggtttattg tgatgaatgt ggaatagttc
    60541 cagttaaaaa ggaagattta ccagttcttt taccaacaga tgttgaattt actggaaaag
    60601 gggaatctcc acttacgact tcaaagcaat ttatgtcaac aacttgtcct cactgtggaa
    60661 aaccagctag aagggaagtt gatactatgg atacattcgt tgattcttct tggtatttct
    60721 taagatatgt ggatagcaat aatgaaaatg aaccatttag taaggaatta gttaatagat
    60781 ggcatccagt agaccaatat ataggtggag tagaacatgc tataatgcat ttactttatg
    60841 caagatggtt tgtaaaggca tttaagagta tgggaatggt agacttcaat gagccattta
    60901 aaaacttact tactcaagga atggtactta tggatggttc taaaatgagt aagtctaaag
    60961 ggaatacagt atctcctatg gatataatag atgagtatgg agcagatact gcaagacttt
    61021 tcgtattatt tgcagcacca ccagaaagag atttggactg gtcagagcaa ggtgttgatg
    61081 gatgctttag attcttaaat agggtttata gattggttga cgagttagca gatgtggtta
    61141 aaaaggatgt agagtttgga gaattaaatt cccaagataa ggatatgaga tatactatac
    61201 actctacact taaaaaagtt actgctgatt taagtgaaaa attcggattt aatactgcta
    61261 tatcagctct tatggaatta ataaatgata tgtataaata taaagagtta gataatataa
    61321 acgaagcagt tataaaagaa ggtgtacaaa ctatagtaac tataattgca ccatttgccc
    61381 ctcatttagg tgaagaacta tggactatga taggtaaaga aggaagtgta tttgatatag
    61441 actggcctaa atatgacgaa aaagctttag taaaagatga aatagaagtt gttgtacaag
    61501 ttaatggaaa agttagagga aaattaactg ttaactcaaa tatatctaaa gatgagatgg
    61561 aaaaggtagc tttagaagat gaaaaaataa aaggattagt tgaaggtaaa actatagtta
    61621 aagttgtagc tgtacctaaa aaattagtaa atatagttgt taaataactc aaaaatatga
    61681 acaaaaatat aaatttataa aataaatgag gctgtctcaa aatagagata agcctttttt
    61741 cattgttgaa attataaaaa tagatttgat tttatacaaa aaaatgatta aagaactaaa
    61801 aagttcattc ttatataccc tagttgttgt tttaaatatt attataatta atgttaaatc
    61861 gagttaatgt attaagtggt atgtaaatca ttcagtttcc aaagtgttgt ttatcaagga
    61921 actgctctaa gcttaaacga aaaaaatata attattgtat tttgaaattt ttttctatat
    61981 aatgaaaaca ggcaaaaaag gtgcatatct atgctttata tgaaacaccc agacaacgaa
    62041 attcagattc atataatagc taccatgttt ctaaaaagga acttgtaaaa aagatagcgt
    62101 ttcaacttcc cagttgatta aaattatcag caggaaaaca agtatggtca gcagtggtat
    62161 tctaatgggt gttgtcgata tatccaagtt gggattgtct gaggatgtta tcaaataact
    62221 tgtgataggt gcagtagatg tggagattcc tgatacggat ttattctcag gggatggttg
    62281 cttcgggaga tatggagcgt aaccagttta ttgatatggt aaccattttt tgtctaattt
    62341 gatgaaagaa tcccaagaat accatacaga agtaagacag gaattaactg gtggtataaa
    62401 ctgataaagg caaatttaaa aattttgata ggatgatttt aagatttatc ttctattttg
    62461 ttttttagaa ataattgaaa tgttatgagg aggtatgtac aaatggagac tgtaacaaat
    62521 aatcaatcag gtgtagaaat tcaactcagt ctgtttgaag ctatcaaaga tttattgtta
    62581 attaatccta ttttcttgtt gggaattatc ttgattggta ttttcttagt tgtaatattc
    62641 aagaaaaata gtgatattcc aaaggtaaaa acatctattt tatcactggc aatgtattac
    62701 tacttatgtt taacactatc acatattgtt ggtataccta cattcggtga atatataaga
    62761 ctgtcacagt taggggaaac gttctttaat ccaaacataa atcttattcc ttttagtgat
    62821 ggatttagtt tgagttttat tttgaatatt ttactttttg tcccattagg ttttttatgt
    62881 ccgcttataa gcaaaacctt tgaacgtttg agaaatacat tcttgattgg ttttggatta
    62941 tctcttttta tcgaaactat tcagcttttt acgttacaca gagcaaccga tatagacgac
    63001 ttactcacga acgtaattgg aacaataata ggctattttt gcttcaaact gattgctaaa
    63061 ttgcgaattg taaaactaca ttcagatgat gactctatgg aacaggatta cacagtatgt
    63121 attccgattg ccattataat agttgccctt atattaggat tttttagtta agttccaaat
    63181 agctaatttg ggaattatgg aggtcattaa gtgaataaaa ttacttttat atgtttaggt
    63241 gtaaaaagta tggagaagtc aattaaattt tatagagatg gattaggatt ttagattaca
    63301 aacttttagt ttaccaagga gatagcaaag tcgtgtgcca aagggtaacc atttggaaat
    63361 ccagacaaca taacagatag tatgttacct tttacaggag catactatct gttatattgt
    63421 caacatccta ttttatggtt tgtgtgtagt ttcctgtaaa ctgaactaaa taattaaata
    63481 gaagctatta gaattaataa taacagatag atattaataa gcataaacaa atagtaaaat
    63541 gtgtagatat agacgttttt aagtgaaact attataaaat aattgactga taatcaactg
    63601 acaaaaccta tttttttagg tttaactgac atttaactga cagtcagttt ttactattta
    63661 aatagaagtt cgcttagatt gtcggaagct tctttgtcca tttctttaag tacatgagaa
    63721 tatctattca tagttatttt tatatctgta tgacccaatc tttcagaaac aactttcata
    63781 ttagttcccc ctaaaagcaa cagagtggca cttgtatatc ttaaatcatg tattctaatc
    63841 ttttttaaat tatttttttt gtaaaattgt gaaacgtttt tcttagtgaa gaaggtagaa
    63901 acggatttaa attggtgttt agacaaacta agttatttct gttttccagg ataccttaca
    63961 attttaattt gctttgtctt agtttttcaa ttttcaattt ttcaattaat tcttttggag
    64021 ctgataaagc tctttttgat tttggtgttt ttggctcttt aaaagatatt ttgccattag
    64081 aatagacaag aatttgatta acatttatca gattgttatc taagtcaaca tctgaccacc
    64141 taagcccagt agcttctcac attcttaaac ctagaagtaa cattaaaaga ataggtattt
    64201 ctatattatt accaagtaac ttttctatta gcaataatac ttcttctcta ttgtatattt
    64261 catttgtaga atatttttct ttagaaggaa gttttataaa atcacatgaa ttttcttgta
    64321 tttctcttaa tctatacgct tcccttatta cagaacttag aaagctatac cttactttag
    64381 cactagtaaa ggtagaatta ttaaagttat aatttacaaa agcttgtact gaactaggat
    64441 ttacttctgt gagttttaga ttcttaaaaa aggttctatg taatttttaa cccaagattt
    64501 tgtatttgta acagtatatg gagaccaatt atttttattc atgtctatat atttataaca
    64561 tctttctaca aatgtcatac cttttggagc aacaaactta ttattattta tagtagactt
    64621 tatttcaatt aaatgttttt cagcatcctt tttcttttta tagcttccat aacttttttg
    64681 tttctttttg ccagtttctt attccacata tacatagaat ttttcccatc tttttcttat
    64741 aaaagctgat ttgatattca tatatgtacg ctccctttat aagttagttt tataaaagaa
    64801 cagttggact gctctaatta tgtcattatc tttttaattc tttacagtta cattataaca
    64861 cgtatttgta tacacttaaa ttaacaggaa gataaatatc attaaaggag gaaaagaaaa
    64921 tttaatgtag aattatgtaa gatatatagt atttcatata taaaaggggg agatattgtg
    64981 aaattaaaga aattattatc actagggtta gccgtgtcaa tgtttgctgc tggtcctata
    65041 tcagctaatg cacttgatac aatttatact attcaaggaa aagataaata tgaaacggct
    65101 gctcttatag ctgatgaaca aaattatact acagctatat taattaatgc agacagcaca
    65161 atggctgatg gattaagtgc gagtggactt gcaggagcaa caaatgcacc aattttttta
    65221 actaagaaaa ataacatacc taatgcaact cttaaaagag tagagaaagc taaaaaggta
    65281 tacataatag gtggagaaag ttctattgat aaagcaacag aaactcttct aaaagataaa
    65341 ggaatagagg ctaaaagact tcaaggtagt gatagaatta agacaagcta taatgttgca
    65401 aaagaaataa actcaattaa caaagtaaat aaagttatat tgactaatgc ttttaaagga
    65461 gagcctgatg caatgagtgc tgcacctgta gcagttagag ataaagcagc tatagtatta
    65521 actgatggaa aaagtgttcc atttaataca actggtgtag aaagttatgt aataggtggt
    65581 acttcatcaa tgagtgacaa actagttaat gatactaatt caactagatt aggtggagta
    65641 gatagatatg atactaataa aaaaatagta aataagttct ataatggcgc aaaagaattt
    65701 tatatagcta gtggtactga tttagtttat gctttagttg cttcaccaat ggctaaaaat
    65761 aatcctattg tactagttga tattggaagt aataaagata tacttaaaaa tgctgcaaaa
    65821 gtgactggga taggaaatct aagtgataaa attatgctag agtgtgaaaa taccatcaat
    65881 aatattagtc ttccgtcttc aaataaaaat ataatatgtg gattaaagat tgattttgat
    65941 tcaaagcaca taatttggca agataaagga agttatcttg aatgttatga tgataacctt
    66001 gaatattata ctgaaaaata taaagaccca acagttccta taaatataga aaatacaagt
    66061 acacaaaatt tagatgtaac aaaattaaaa gtttatggag aagctaattc aacattatat
    66121 atggggcaat atgctaaaat aaaaatggat tttaatagtt tcggtgtatt aaagccagga
    66181 gaaaaatgta ctatttattt agatataatt tcattagatc catcaagaag catgacatta
    66241 acattttctt atgtaggtga taaagaaaat tataaatatg aacaaggatt ggcaagtaga
    66301 atattatttt ataacccaga tggagaagat ttttttgaat ataaataact agtgggtatg
    66361 taaattaata agggttttat aagtttaatt tttttatttt cgttttatat taactatgtg
    66421 gtatgtaaat gtctcgatat tgctcatatg ttgagttatt atatttagtt tcatatgaac
    66481 tatatggatt ttaaaattaa aaatacttaa aaacatttac tttaatagta ggtgtttttt
    66541 tgattaaaag aatattatta taatgtaaaa agtaataaat aggtaaaata tgtaagaatt
    66601 atatgttata atatttttag caagaagatg taatctacaa tttatagagt ggagttcatg
    66661 tatcaaaaaa ttatcctccc gacgctaaga agggaggtga atatacatgg ataatttttt
    66721 acaaggcata ctagcaagtc tatctgctag cttaatagtt tatatagcta gcaaactatt
    66781 tagaaagcgt aaaaaaccac tcaaagcggc aactaagagt ggttgggaat ttgatttaaa
    66841 aatcagattc cataaaacta agtaatttct aaattatgaa ctccactcta cagcaaaata
    66901 gattgtagtt cttcttgctt ttattatatc acaaattggt acagatattc aaaaataata
    66961 tttttatgat ataataaagt catagaaatt ttgcagtgtt cgattttttg aagaaattaa
    67021 ggcttaacag ttgaaatata aggcattgag gacttgtgat aagtgttatc aattgcacta
    67081 ctcatggttc actgcaaatt tgagagattt gtatatgtgt aggcattgga aatactcaat
    67141 ttattttggg gttttatatt aactatatgg aatgtaaata gtatttcagc aattttactt
    67201 ttaataactt tatcagcgtt ttatattaac tatatggaat gtaaattcaa tttaccgttt
    67261 ttttcaaatc tcacaacatc agagttttat attaactata tggaatgtaa atctatcggc
    67321 ttcttgaaaa gcctcatctg ctctatttag ttttacatta actatatgga atgtaaattt
    67381 cattaaatcc ccaaccgaat tatctttcag catttgtttt atattaacta tatggaatgt
    67441 aaatcatgct gataagaatc tctatgaact tcggagggaa ccggttttat attaactata
    67501 tggaatgtaa atttgggtat tttgctaaaa ataaagctat taaattagag ctttatatta
    67561 actatatgga atgtaaatcg tattaacacc tgttcggcac tatcacaata aacacaagtt
    67621 ttatattaac tatatggaat gtaaattgta tccaaaaaat tacaataatc atacgaactg
    67681 ctaatataag cagtcaatat atgtgtacat ttatccattt tatctctaaa catataaatt
    67741 attatccccc taaaaaactt tcataaaaac aaaaagaaca atatctcttt ggcaactggc
    67801 taacataact cataagatat ttatataagt cttagtccct atagctttgc gtcactagat
    67861 ttctctagtt ttgccgattt agttttattc tataactaaa taatacaata gaattagtta
    67921 ttattcaaca agattgtttg aaaattgaat aaatttatag gtatgaacgt aatttcacac
    67981 ttaaaaacag actaaatacg tagaatatat agaaaaattt acctgtagtt tttgtgataa
    68041 aaagctccta ttattaattt aagctagata agtttgagga agtgacataa attgaaagaa
    68101 ggaatatatt atgttgaata aaaaattacc agatgcagaa ttaaaaatta tgaaatacat
    68161 atggaatact ggttataaaa ctgtaatatc aaaagatgtt gcagattaaa tagaaaaaac
    68221 atatgcttgg aagcatacaa ctacaattac acttttagct agattaacta aaaaaggttt
    68281 tttcatatcg cagagaattg ggaaacatgt acactataga gtattaataa aagagaaaga
    68341 atatctcaaa atagagggaa aaagaatttt tggaggtcta cataacaatc cattatcaga
    68401 actaatttca aaattacatg atggagaaga aataactgaa gaaaaaataa tagaaatagg
    68461 aaattggata aaaagctgga aagatgaaga ttaataaata aaaggtagct actaatataa
    68521 gtgctacctt ttttcttgtg gataatattg gggataagtt gtggaaaatt tgtgtaaaaa
    68581 ttgtggataa aatattttgc tgacatttaa ctgacataag tattagattt tgatttaaaa
    68641 atgttgaaat atcaataaat aattaaatag aagttattag aattaacaat agattccttt
    68701 ttcaaagaaa tctttgattt catcaaggtt atcagttttt ccaagtgcta agataagttt
    68761 tattctagct ttttgacctg gtaagtcccc accaaatata caaccaagat tttttaaatc
    68821 tctaccagaa ccaaagtaac cataactatc gaatactcta cctgaatgac atctagaaac
    68881 tataactaca ggaagtcctt tttctctagc atattcaact ccagaaagca tttgaggggg
    68941 aatattacct ctgcccattg cctcaataac tataccttta taaccactat caacagcaaa
    69001 tcttataaag tcagcatttt ctcctacata tgctttaaat aaggcaactt tagattctac
    69061 cttatcagta tctataattg ttctatttac aatatctctt gtaaggacaa gttcgttgca
    69121 gtcaattatt cccaatgggc cactagttag agatttaaat gtatttagag aaagagtatt
    69181 tgttttagta gcttcagaag ctaataatac ttcattgttt aaaactacaa ggactccttt
    69241 tcccatagca tctttggata ctgcagtaca aactgatgca gataaattac ttgaaccatc
    69301 atatccaagt tcagaactac ttctcatagc acctgtgact attacaggtt tgatgttgtc
    69361 aattgtaagg tctagaaaat aagctgtttc ctctaaacta tctgtaccat gtgttattac
    69421 aacacctgta atatcttttc ttgctaataa atcatttaca tagtttttca attccatcat
    69481 tctataaggt gttatgtgag gtcctggaat ttcatcaaaa ttaaaaactt caacatctgc
    69541 aactttatca atgttggtaa ccattgatag tatttgttca cctgataaag ttggtatagc
    69601 tgctccgact ttatcatcta ctgtcataga tatagttcca ccagtaaaaa ctatggcaac
    69661 ttttttctta atactcatac tattctctgc ctttcataaa taaaatttat aattccgata
    69721 ggattatatc aaaaaaagta gttaaggtct acataaactc ttttattcat ataatttaga
    69781 tatttcagtg taatataatt atttcttaat tttttgccat tcaacgatat aaccatttaa
    69841 tatctctctt atggcttttc ctatcttagt ataagcttca tcatatagat ttgctagaga
    69901 tattctaatt gaccattcag gaccatagaa tccatttcca ctaagtaaaa ctactgaata
    69961 gtcattagct aatttataaa gaacatctac tggagatgca tttttactta taaatttaaa
    70021 taagccttct ccgtagttta atttagccca ttcttcaata tcaaattgag tgtaatatgc
    70081 agcattgttt ttgttttcat taattggaag ctctaaagct tcaaataata gtttttgacg
    70141 tctatggcag atactcatat tgagtttttt gtaggcatct actttgtcaa tcaatgcaaa
    70201 agcagagaaa aacgccattt gtacttgctg tggagtagaa agaccagcag tatggttgag
    70261 agcaacaagt ctgctatcag caacaactct ttccataaat gaaaggctag aagggttaag
    70321 actcatatca ctgtaacgct tatctactga tttttttaat tctccagtta aatcatttat
    70381 tttcttatca aaaacatttt tcttatgaag ggcaaatgta ccaagtctcc atcctgtaac
    70441 tccaaaatat tttgaataag aatatactcc aacagtgttg taaggtagtt ttgacattaa
    70501 ggatgaaaaa tcttctacaa aagttccata tacatcatct gatattatca ttaaatcttt
    70561 attataattt tcaattacat ctattagatt attacaagat gtttcatcca tagctataga
    70621 agcaggatta ttaggattaa caacgaataa agctttaata gatttgtcac gaagtttctc
    70681 taattctttt tttgtatatt gccatgtgtg agcacctttt tcatcaactt cattagcatt
    70741 tatatttacc actttaaagt cgtaacgagg aaggttaggt atttcaagat aaggtgtaaa
    70801 tattggagtc attaaggcta ttgtatctcc tttttttaga agttcatttg ccattaatga
    70861 atcaaatata tagcacatag cagctgtagc accttcaaca gcaaaaattt ctacatcacc
    70921 atatttacct gatatatcat atttcatttc ttgaactagg taatcgtgta ctattttttc
    70981 catatgaggt aacattctat ctggaagtgg atagttatca ccaataattc catcagctag
    71041 ttcatgaaca aattcatctc catcaaatcc aagttcattt ataccaaagt ttataatatc
    71101 tctagctaaa tatgctccag gcatatctat attttcattt ataaatttaa aaaatctttc
    71161 tttaataccc tttttttgag gcattccagc caaatgacct aaatcccaat tagaacgagt
    71221 ttcagtaata gcgaaatgac caaaagtaaa aaaggcttct ctagcagttg aacaagtcca
    71281 gtttggattt ccacgacctg catcaagtaa ttctctgtta ttttcttttg cagtgtattt
    71341 tgcaatatct attaatttgt ccttaaattc aaaagggctt atttttccat atatgttttt
    71401 gatttcttta taagtatgat ttttcatgtt aaattcctcc ttatgtaata agtttcacat
    71461 ttttataata aaataaacaa gttgcaaaaa tgattatact ttaattataa taggtttata
    71521 gaaaaagtaa agtatgaaat taaaataata act
//
LOCUS       DAMJXI010000015        63315 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.015, whole genome shotgun sequence.
ACCESSION   DAMJXI010000015 DAMJXI010000000
VERSION     DAMJXI010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 63315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63315
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.015"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            288..1778
                     /locus_tag="PC465_001298"
     CDS             288..1778
                     /locus_tag="PC465_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2648617.1"
                     /translation="MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGE
                     KPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEEDEQIIYILEAACDSCPI
                     NEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEV
                     VRPCKSVCPTNALGFDRENMKAMIHEDKCLNCGACMSACPFGAISDKSLIAPVARKLV
                     QKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAE
                     RMEKGEAFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFI
                     GPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFG
                     AAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGG
                     CINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK"
     gene            2058..3554
                     /locus_tag="PC465_001299"
     CDS             2058..3554
                     /locus_tag="PC465_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2648618.1"
                     /translation="MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGE
                     KARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRC
                     PINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
                     EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKK
                     LAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNEL
                     IERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVV
                     FIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRG
                     FGASGGLAKSVQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCE
                     EGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEDVNLER"
     gene            3688..4614
                     /locus_tag="PC465_001300"
     CDS             3688..4614
                     /locus_tag="PC465_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2648619.1"
                     /translation="MRKIVLKDILFLVTTLSIIVILLLVTNITTNSKIKSTSESYLKS
                     DKNSVRQNGIQRSTKSSTKNTAFKTTILNTGKSDCILVEIGNKVIMIDTGEDKNGKQI
                     VDRLKEKGINTLDYLILTHLDKDHIGGVDSVLSSVKVKNIIQANYKKDSKQYDEYIDS
                     LKKADIEPVLLKDNMNIVINSAEINIHPASKSKYESSNDYSIITNISYGAHKFLFAGD
                     AEEERLSEFINGNTLKYDFVKMPHHGRYDKLTETFLESISPQYAVITCSEKKEPEEGV
                     LKILERLNIKTFLTSNGEVVINSDGKTLSVNQ"
     gene            4732..4923
                     /locus_tag="PC465_001301"
     CDS             4732..4923
                     /locus_tag="PC465_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648620.1"
                     /translation="MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWAEMDLCAWIPFL
                     ILLLILCECGDVFDGGCGC"
     gene            5146..5496
                     /locus_tag="PC465_001302"
     CDS             5146..5496
                     /locus_tag="PC465_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648621.1"
                     /translation="MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILIT
                     LKRLVFQGNVNEAEEILFDKAKSVNSENMQYIAIEFYTMLMEKTDEELEAMNFSKQEV
                     YQGIEDIRKVLNLE"
     gene            5759..7264
                     /locus_tag="PC465_001303"
     CDS             5759..7264
                     /locus_tag="PC465_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HDF2648622.1"
                     /translation="MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKR
                     VLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRG
                     YELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGAN
                     EYIETTKPIVVVTAPGPNSGKLGTCLSQLYHENKRGNVVGYSKFETFPVWNVPVKHPL
                     NIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQS
                     PTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEEL
                     NLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAVV
                     LNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPT
                     AQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS"
     gene            7654..8751
                     /gene="dinB"
                     /locus_tag="PC465_001304"
     CDS             7654..8751
                     /gene="dinB"
                     /locus_tag="PC465_001304"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HDF2648623.1"
                     /translation="MKHYRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVV
                     ATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEQIRDIFYRYTDLVEP
                     LSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
                     PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIF
                     KKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCH
                     RLKNSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGVDNLLRNVEVNGKQI
                     RLLGVTISNLSDKKETYKDITLFEYMDSIQM"
     gene            9014..10150
                     /locus_tag="PC465_001305"
     CDS             9014..10150
                     /locus_tag="PC465_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2648624.1"
                     /translation="MIEIRNVTKKIGNNVILDDISLAVETGTLVVLIGSSGCGKTTTL
                     KLINKLIKPTSGEIYINGKPISQENEIELRRKIGYVIQNTGLFPHLTIKENIELIPRL
                     KKEKSVEEIEKRTLQLLEMVGLDSDEFLNKYPSELSGGQQQRIGVARAIATDAEIILM
                     DEPFSALDPITRTSLQEQLFSLQDELKKTIIFVTHDMDEALKIADKICIMKDGRIAQY
                     DTPENILRKPANDFVKDFIGEDRVWDNPEYIKARDIMIKNPIAVNSTRTVTQGIEIMR
                     TSKVDSLLIIDRAKTLKGIVTVKDMKDIDDKSILLADIMSSEPLHVNEGDNLVEILNV
                     MNRNSVGYIPVISDENKLVGLITRSSLLSVLSEQFLEMEVSVLG"
     gene            10143..11690
                     /locus_tag="PC465_001306"
     CDS             10143..11690
                     /locus_tag="PC465_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDF2648625.1"
                     /translation="MANFFNFILLQKDKIIELLIQHMSLTVTSILIAIIVGVPLGIII
                     SRISSLRKFVLGFVNLVQAVPSMALLGLLVPILGIGSKPAIFMVVVYSLLPIVKNTYI
                     GITSIDPVVLESAKGIGLTRNQTLFKIQFPLALPIIMGGVRISAVTAVGLMTLAAFIG
                     AGGLGYLVFSGVQTVNNNMILAGAIPSCIIALLVDYLFSKIEVAVTPKGLNPKAPKKN
                     YIALKVISVVVVVSMLFVVFSSSFSSKKDTITIGSKDYTEQLILGNVYAELVEKNTNL
                     KVKKNLNLGGSSVAFNAIKSGELDMYVDYTGTLLVNVMRHAPIKDADEAYNVVKDTME
                     KENQLTLLDPLGFNNTYTLAMMPETAEKYGINTISDLTKYGKEFTFSPTLEFENREDG
                     LVGLSRDYGLKFKDVKAMNGSLRYTALDNNESQVIDAFLTDGLIKKFNLKILEDDKNF
                     FVPYYAAPLVREDTLKKYPELEKVMNMLSGKINEETMRELNYQVDELGKSPEEVAHSF
                     LVKEGLV"
     gene            12024..12890
                     /locus_tag="PC465_001307"
     CDS             12024..12890
                     /locus_tag="PC465_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF2648626.1"
                     /translation="MDNYKKVKQVLWIILFANFAVALLKIIIGNQIKSYSMTADGFHS
                     LSDGASNIVGLIGIFFASKPKDKNHPYGHKKFEIITSLFISGMLFVIAIKIILSAVLR
                     IANPVVPAITIESLIALIITLFINIFVCMYEYRIGTKLNSYVLISDSLHTRSDIFVSL
                     GVLVTLVGVKLGFPVIIESIVPIIISAFIIYSAYGIFRPSIGILVDRVAVDEDYIKEI
                     VFEFNEVRDVHNIRSRGSKSSIYIDMHVMVDPFISVEQSHDLTHKIEKQIQEEINENA
                     QVIVHIEPFYSF"
     gene            13031..13669
                     /locus_tag="PC465_001308"
                     /pseudo
     CDS             13031..13669
                     /locus_tag="PC465_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437122.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
     gene            complement(13823..14941)
                     /locus_tag="PC465_001309"
     CDS             complement(13823..14941)
                     /locus_tag="PC465_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF2648627.1"
                     /translation="MNIKSAFIRKRGEKFHVYVEYIEEMTGKIKQKSYGSYEKKKDAE
                     KHLIEIKSTINSNKFITPSKTTLVERCYKYIMSNEKNWSPYTVINRKSWVKNYIEPFF
                     KDTKLIDINPVLIQTFINTTFNNCTFSSSKIRYRFISSVLKEAYRLREINENPCDFVK
                     LPHKENSSKIEIYNREEALLLIEKLNNSNIEIPILLMLTLGLRLGEATGLRWTDVDLN
                     IGSVSVSQTLIYANNKIEFKEPKTSKSRRTLSAPDELIEKLKIEKLRQNKLKLQGILK
                     NENNLVCLNKDYNPFLPATLRKSFHRFIKKNNLKNIRMHDLRHTNASLLLLGGTNMKV
                     VSERLGHTDIQITMNRYSHVLEEMDKKASDNLSKILFK"
     gene            complement(15449..17113)
                     /locus_tag="PC465_001310"
     CDS             complement(15449..17113)
                     /locus_tag="PC465_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HDF2648628.1"
                     /translation="MNNENEQLKSDLLINDEKIKNLNFKIPWYYSLWTISILILSTFS
                     TYSISFIVAIIFLFKRNKIMKKHKDSISILLSDVEKINNKYILLNDEIKMKEKHFEDL
                     CESNENKLKELSNLLDKKKVEIDKFDSENQDKFKLIEELKIEKERLDNLIKDKNILKD
                     NINTLNAHLEELKDEREELRDINTTLKNKKEELKRLSEELIQTEDEVLLQSFGLYNPK
                     YDFENSDEYMEKLKEIRERQKLLIRNKTGVKYSDSWTVDGSIQKGRTMTNQNIKTALK
                     LFNSECDIAMSKVSFKNIDSIEKRIRKAFTDTNKLNTSNKVSIKENYLNLKIDELYLY
                     YEYLQMKEEEKEEQRALREQMKEEALVQKEIENQKRKLKKEELQFKNELLRLKSTIPE
                     DENDKLEWEQKINSIEEKLALLSKDLDDVLNREQNTRAGHVYIISNIGSFGENIYKIG
                     VTRRLDPTERINELSSASVPFKYDIHATIFSEDAPKLESALHKAFDNKRVNKVNNRKE
                     FFKVTLDEIRTEVEKNFDKTVEYTKLAEAQEYRQTLKIQELNKKLA"
     gene            complement(17384..18832)
                     /locus_tag="PC465_001311"
     CDS             complement(17384..18832)
                     /locus_tag="PC465_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HDF2648629.1"
                     /translation="MSILNLFRKNKNKNNVDCNEKSNESKQSYNDSTTLSLECNSNSP
                     HNIEVKNEINKVLNVSCNDTTNLYELEKQAREKSDALYDIHTNSINKFNPQNNILETD
                     TKPLTSIEKSFLKYIIGENIYEPYIATYWTYEYNINYSYLISKFFNMDYLKISNYIED
                     LTKLTVSELKEILKSNNIKSTGKKAELIERIEKEISCKDLSNFFNSSNKYYALTDKGK
                     ELLKDVRKSVTKNTDLEDQCLELIYIDKYEEAYDLICKYESSKNIQRGININWENHKI
                     TPMKIESYKAIKELDINLKDTLLDNIIKSSYILCDMLGNNSKTSILVKRLAGEKIDNI
                     EINNAINSINDVIYNHSTITYNANDSINNKNLHYMDIVKNNKSIPFEVNNKNYNFKIN
                     ENEIYFFNILKIKMYENELKNNFVFDRMSDGAFNVFDTSDNFIGKVKLQGRKKWIMYM
                     KNEFGSEHIYGELIHLIDGIDAWIKYSKEYLK"
     gene            19329..19469
                     /locus_tag="PC465_001312"
     CDS             19329..19469
                     /locus_tag="PC465_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648630.1"
                     /translation="MEKSKKLLIDTGDTLNKLRENNSEKLEKYIELLKEYYKQENKKE
                     RE"
     gene            complement(19484..19849)
                     /locus_tag="PC465_001313"
     CDS             complement(19484..19849)
                     /locus_tag="PC465_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2648631.1"
                     /translation="MIGYRIKELRKEKDITQKELATFLGLTPKMISFYEKEERFPPHD
                     IILKLSDFFNVSTDYLLGKVNVKNIDNLSELELIENLNFSDDIKEALKLISELSPSSQ
                     EKMFKIAKVFLEEELNEKK"
     gene            19994..20230
                     /locus_tag="PC465_001314"
     CDS             19994..20230
                     /locus_tag="PC465_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2648632.1"
                     /translation="MNKLKDFRIQKGLSRNQLGAELGLTSRYIAFLENGERVPSLNTA
                     VKIAAYFNTSIEYIFLKNNCTKSTFKEKGAEKYE"
     gene            20223..21014
                     /locus_tag="PC465_001315"
     CDS             20223..21014
                     /locus_tag="PC465_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
                     /protein_id="HDF2648633.1"
                     /translation="MNNLQVIERNNERVLTTQQLADVYETDARNISNNFNNNKDRFIE
                     GKHYFLLQGDDLKNFKGIHTEYENLKFTSKMYLWTERGANRHCKILDTDKAWEQFDNL
                     EETYFKVKQHKPTCIEDVLIESLKEMKDLRLQVNQANSIALEAKTEVETIKDVVSLDS
                     NSWRTNTHQLIARIAKKQGGFEHINMLRTESYELLNKRFGVDLHRRLINKRRKMAEEG
                     VSESKREKVNNLDVIQDDKKLIEGYVAIVKDMALKYGISSDLSKN"
     gene            21084..21413
                     /locus_tag="PC465_001316"
     CDS             21084..21413
                     /locus_tag="PC465_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2648634.1"
                     /translation="MSVALQFIDTKDLVQELMRRDDTTDIIKMFLGREGIKRMELMTI
                     EEFCEYLKISDVTARNMAREAMITKDFIALKIGRKYMIDRISFEEFIMKNAMKDRDVM
                     KKRKGVI"
     gene            21719..21964
                     /locus_tag="PC465_001317"
     CDS             21719..21964
                     /locus_tag="PC465_001317"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648635.1"
                     /translation="MKSRQELIKDIEKYRKAQYLIYLDIVQRAWADRSLTADEQDRIK
                     QEAYAEYKRIERDTEEAEELLMREEFETDRPLAVQIM"
     gene            22047..22556
                     /locus_tag="PC465_001318"
     CDS             22047..22556
                     /locus_tag="PC465_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HDF2648636.1"
                     /translation="MSTLYELATDLLEIEEGLTEITGNETEKLEEIKEIIKQEIQNKN
                     TRIVSVILNIDSDINSIDSEIKRLQELKRVKKNTLDRLKSNIKDCMELLGTKKVETVL
                     GNISIRKSAGSLVIEDEEKIPAIYKTVEQVVKVDKNTIKDFIKKGHEVEGCRIEYGTT
                     LTIPKAKKE"
     gene            22566..23150
                     /locus_tag="PC465_001319"
     CDS             22566..23150
                     /locus_tag="PC465_001319"
                     /inference="COORDINATES: protein motif:HMM:NF016302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HDF2648637.1"
                     /translation="MEINNIYIKLMDVRVKFSKLNLKKSGENKFANFKYFELADFLPQ
                     ATGLLEEAKLCPIVTFTNEYATLTLINGENPSEQIIFTSPMRDLQLKGSNELQALGGI
                     ETYQTRYLYIQLLNITESDTFDATSGKNEAKSNSNNRILTDKQLSRLYAIASNANVDK
                     ESLKEKVFKRFGKEIKDLTKQEYDTICNAYENKQ"
     gene            23165..24046
                     /locus_tag="PC465_001320"
     CDS             23165..24046
                     /locus_tag="PC465_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HDF2648638.1"
                     /translation="MGIIRVSKDKDNPYVVLNKTCLEDVKLSWQAKGLHSYLISKPDH
                     WKIYVNDLYKRSKNGRDATANILRELIENGYITRTPCRDSNTNKMLGGYDYQVYEIPL
                     ENPQKLKSRKTDFPETGFPGNRVSRKPENTEVVSNDFKVNNDITTIVINEQSNKDKTT
                     YIKKYFEKYIGVITPNNFIELMSYLDDGMEADVIIRAIDEAIANGVKNYKYVKTILNN
                     WIEAGVKTNLELTEYQNEFERKKKSKQEKKQSNNKAVNTHNVNKNKFANFNQTFTQYE
                     EKELDEIIKKSQKEKFK"
     gene            24105..24278
                     /locus_tag="PC465_001321"
     CDS             24105..24278
                     /locus_tag="PC465_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HDF2648639.1"
                     /translation="MARIYAQRSGSLNEQDRLELLRLLGKAGYTVKIAREKQNSKTTY
                     TYFVEYTEEQEEK"
     gene            24294..24701
                     /locus_tag="PC465_001322"
     CDS             24294..24701
                     /locus_tag="PC465_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2648640.1"
                     /translation="MNTITLVGRLVADAELKYLPNSGTPKITFSMAVDRRFKDKNGNK
                     ITDFIQCEQLGKHVENLVQYLVKAKPIYAVGELNIYNYKDENGCWKSITKVNVNALEL
                     LSSKNDNNAKQEYVPPGLDPQGFQAIDDDDIPF"
     gene            24770..24991
                     /locus_tag="PC465_001323"
     CDS             24770..24991
                     /locus_tag="PC465_001323"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648641.1"
                     /translation="MRFEIGKTYKFDREKFIACNGIEHYKRCEELWIEDVEDVEFTVK
                     KIFDDGYICYPKEFWFNFGVVSEWCVEVK"
     gene            25009..25389
                     /locus_tag="PC465_001324"
     CDS             25009..25389
                     /locus_tag="PC465_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648642.1"
                     /translation="MAKIWVDAGTFLEKTIDIEDMFELNLRKVRKRNEKIKNEIEKKI
                     KDEDSEIKITNRGGPGKSIKVFNINTREVKILKSAKEASKYIKVSCSHASYLARENKS
                     TEDGWKVEYIQEVSDGISKCGTSN"
     gene            25358..25507
                     /locus_tag="PC465_001325"
     CDS             25358..25507
                     /locus_tag="PC465_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648643.1"
                     /translation="MVLANVEQVIKLAEKILNKKKCSVNKAIDIAIKILSKYECEGML
                     RNESN"
     gene            25494..25943
                     /locus_tag="PC465_001326"
     CDS             25494..25943
                     /locus_tag="PC465_001326"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648644.1"
                     /translation="MSLIEYRGYDFENKKWIYSKTIMWSNAVDCLLMLKEDFKWQKVC
                     NVGICSEEWAANNQEIFEGDILKENYNPRNRSSYGIVKRDFNSIKLYLEWHYLKKLEG
                     EWIELINKTEIYHSRDYKIVGNEFDNLEEVRAEFLERKESLENEYLS"
     gene            26045..26221
                     /locus_tag="PC465_001327"
     CDS             26045..26221
                     /locus_tag="PC465_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648645.1"
                     /translation="MNDRLEMINASVNYIQMICESSNIAIIAERGRVRILDLETKEKY
                     DLLKNKLEEMLEEI"
     gene            26335..27024
                     /locus_tag="PC465_001328"
     CDS             26335..27024
                     /locus_tag="PC465_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648646.1"
                     /translation="MDLNKIMNDALVELEENGFVEEVVKKQLAETIKRVVNEVFGNWG
                     DFSKKIEKHLSENININLDKLDIQKYNVLVATTVKEKIDMTMKVEAIEHLKRNLDNML
                     VGAEKEYKMSELLEILKMDKYDIDEYEGYEDCITFILDENKYGSGWIEIDKEPNKSKY
                     RCEHSILLRKDGTIASYRYENREISSKDIMSGFDNFGDLLFKIFAHGSKIILDLGNDI
                     EDYDLTNGEDY"
     gene            27042..27263
                     /locus_tag="PC465_001329"
     CDS             27042..27263
                     /locus_tag="PC465_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648647.1"
                     /translation="MSKYVLRWQKGLLLDERKINYSCGSKEMLKKKAELLAKDDKILL
                     VTIDKVEEVIKDTRSQKMAEYFEDEGVEV"
     gene            27260..28255
                     /locus_tag="PC465_001330"
     CDS             27260..28255
                     /locus_tag="PC465_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HDF2648648.1"
                     /translation="MIIHKFIIHVLDKNSDTPILNDFEGRVSQDIEAFFQKKISKVSR
                     DNDIRTAVFNDYSNNLIKKCCEQIIYDESSFLNNSKEIAAYLFDVMKLNATLESCDLS
                     ICLYSQKDEKKVAILKLDYNNSYTHSIEFKDDKFNIQMSKNEINIQETKAIKIGALIG
                     LSGINDEYHLKVLDKDAEKEEANSKFVTEFLNATKVKDDKYKTKMFKAFVDSYIAHLY
                     SDMKQGEDVRGMLLYMLREKQKLDINEFADKAIKDDLKDSFKDHIEEKGIESFNIDKK
                     WVEKNLKNRCIKTDTGFEIKGKMEYFEDFMKYGIRHNGNGTVDIVIKNVNFYNEK"
     gene            28264..28989
                     /locus_tag="PC465_001331"
     CDS             28264..28989
                     /locus_tag="PC465_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase family
                     protein"
                     /protein_id="HDF2648649.1"
                     /translation="MKYVASFSGGKDSAAMLLLILEKGLKLDEIVFIDTGLEFKEIYD
                     IIDDFEKRINFKITRIKAEKTFEEYFYTVNQQGKRKGQIWGFPYTLGAWCNSRLKLAP
                     ANKYFNKLGEHKRYIGIAFDEPSRYKRLEKNCIAPLFEEKMTEKDCLKYLKEKGFYYE
                     IHHRFKRTGCYLCPKQSLESLRTLRRYYPDLWGDMLKLDKDSPVPFRANGVTVNDLEK
                     RFSNEDIENERQISFFQTEKVSI"
     gene            28986..29153
                     /locus_tag="PC465_001332"
     CDS             28986..29153
                     /locus_tag="PC465_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648650.1"
                     /translation="MTNKEMCKSKNLDEREVCKKFRKEICASCINDKGDCESKDCDTA
                     YKNWLEDIYYV"
     gene            29146..29520
                     /locus_tag="PC465_001333"
     CDS             29146..29520
                     /locus_tag="PC465_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648651.1"
                     /translation="MYSTYKVKLKTKKTLEQLRKQGDINFGSSEEGLKRALKYNNLID
                     GLEVTVIKFKDVYCLANCDEKDVEKIRDAYYLLEQDKYFGCYINEYERFKKDWKNGSC
                     DGEASMVFSDDEIEIIEKLREG"
     gene            29523..29705
                     /locus_tag="PC465_001334"
     CDS             29523..29705
                     /locus_tag="PC465_001334"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648652.1"
                     /translation="MNKRIKMKKRLIHKKCDERCVNYDFVISNNLITCNVCIGCKYKE
                     NMDKVCEENYKKLRSK"
     gene            29803..30018
                     /locus_tag="PC465_001335"
     CDS             29803..30018
                     /locus_tag="PC465_001335"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648653.1"
                     /translation="MNKCEGCKYRAYEEDGEVYFYSDGSYEGGICVGDTVILQSFKDK
                     KFTGIEINKEIEYFVKLGNGYVELGIK"
     gene            30036..30479
                     /locus_tag="PC465_001336"
     CDS             30036..30479
                     /locus_tag="PC465_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HDF2648654.1"
                     /translation="MKVNFVIDGEPKAKARPRMSTSTGKAYTPDQTILYENWIRLMYN
                     STVKHFFEGNVKMTVICYFDITKKDREALQKNKVNTKAYKDAIGKVEGLIRPNKKPDL
                     DNIIKSVADSLNGIAYKDDSQIVEVVSKKYYSDKPRVEVVLEDII"
     gene            30793..31647
                     /locus_tag="PC465_001337"
     CDS             30793..31647
                     /locus_tag="PC465_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HDF2648655.1"
                     /translation="MNENINKEITVLGTLEVEGMKFHDIEGGFGKGKKAMLVKDIAEI
                     HNRELKHVNELINSNIKRFKTNVDIIDLKVSRSERLGDLKANPSKGLGYEDVGYSKQS
                     FNQSRNIYLLSERGYSKLLKILEDDKAWEQYEKIVDGYFSMRKELNNPLLSASKELQA
                     IFMLDKKQEVLETKIENVNEKLENFMDDAPLFNIECECIVKEVKRVATKSLGGHVSKA
                     YKNKSLRGKVYSDIYHQIKREFGVDSYKAIKRCQLDKVLEIVNNYKLPIVFEEEIRLL
                     NSQLSIVS"
     gene            31737..32225
                     /locus_tag="PC465_001338"
     CDS             31737..32225
                     /locus_tag="PC465_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648656.1"
                     /translation="MDNNINKKELFKKVEGRLHHYKFLSAEIKNLELDIESRENEIFG
                     CKAVGYDEKVSPTYAFNSSVENEIIKKERDITRLKKLKKDKEIEKKKIENALTCLDIR
                     EEHFFKLFYNSRMKNSMVYISLEMNSDRKTCRCVRERLVYKIMDMLYPRIKENELPLF
                     KN"
     gene            32800..33690
                     /locus_tag="PC465_001339"
     CDS             32800..33690
                     /locus_tag="PC465_001339"
                     /inference="COORDINATES: protein motif:HMM:NF022633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2971 domain-containing protein"
                     /protein_id="HDF2648657.1"
                     /translation="MIQESIRKNYIEYMDNYGFSEAAKYKNKELKNKKIYKFIPFTDE
                     LECENNNCKKCPYINKNQRTINSLINKKIWLSKSNNLNDPFELKIIYADKESASKKTY
                     DSNVLNYMLDVIISNVYLTCFTSDFKNNMPMWAHYANNYNGLCLEFKIVNPKNIYPVI
                     YEENDRIKFNNTLSDYLTLCIKDFKGELDEIGQKYQQELAKVISTTFAYKDYVWNYER
                     EYRLLYSDGEPREDVKGILLNMKETGIELTGIYIGNRIDEKYKTDIKNIAKENTLDLY
                     EVYMDENSNKVSLAYRPVEI"
     gene            33882..34901
                     /locus_tag="PC465_001340"
     CDS             33882..34901
                     /locus_tag="PC465_001340"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648658.1"
                     /translation="MSIKVKVWAKLPYIIKLEEEKDYEFSFLFDDFDLFKLNMRFNDE
                     NDFLIYNNEYPGNVCQHIELEVIYKYVDYTKYKTTKCINSNDNYFEVEVPLDKTTEIF
                     GCMNKRLNEILNFLREKSNMFWIDEFNLTHINYHSENEVRFNFYSPNVNPSSVVTSFI
                     EHTDYYMISKNFKTNNVGEDTFKNFDSNKIKMKVFNEYIDKAEKALYEYNYENFIIYC
                     SISVESFIIQYIDEIANQDDIIYKQLEKTNSNYINLYYNVLLKYLTGKSLIEVDKKAC
                     THLTRLYRLRNSLMHKGIIDSKSLEKAGIMKLDFNECNKILDSAKTSFKLVKSITVKP
                     KNDIN"
     gene            34983..35408
                     /locus_tag="PC465_001341"
     CDS             34983..35408
                     /locus_tag="PC465_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2648659.1"
                     /translation="MAKYEYWITEEGLIKIEGWARDGLTDEQIAFNIGINVKTLYDWK
                     KKYSNICNALKKGKEVIDRQVENALLKRALGYEYDEITYEEGQETKRVTKQVVPDTTA
                     QIFWLKNRKPAEWRDKRDIEHSGNLGDITIKVGDEEYGN"
     gene            35398..36639
                     /locus_tag="PC465_001342"
     CDS             35398..36639
                     /locus_tag="PC465_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HDF2648660.1"
                     /translation="MAINLEINPDVFNPIYLKHQLNNNNRYQIYFGGSSSGKSFSLAQ
                     RTVLDVFKGNRNYLIVRNVQSTLKRSCLNEITKAINNFKLNEYFQVNKTDMIITCKLN
                     NKQILFCGLDDVEKVKSITPIDGVITDIWVEEATETDYKAVKQLDKRLRGKSKVVKRL
                     TLSFNPILKDHWLYTEYFDIWEDDKQYVEKDNVSILKTTYKDNKFLAEDDIKALENES
                     DKYYYEVYTLGNWGVLGAVIFKNWRVEDFSDIESTFDNFRHGIDWGFADDPFAYVKSH
                     YDRMRRKLYICDEIEAVGLLNREAAPLVSKKANGDLVICDNASPKDVAEFSDLRINAV
                     SARKGAGSIEYGIKFLQGLEIIIHPRCQNFKNEINKYKYKEDKNGNILPIAVDKDNHL
                     IDALRYSLENDMEYGGISFLK"
     gene            36644..38083
                     /locus_tag="PC465_001343"
     CDS             36644..38083
                     /locus_tag="PC465_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF2648661.1"
                     /translation="MLNIYISETDLIKAQLKKESTFNLAKVIEHYILKHRPEKYQEGE
                     AYYYGNANIKNKRRYYILDGAKVDDFTKVNNKAVNNYHKLLVDQKVGYSVGKPIVFNA
                     DDNNFTKLLNELLGEEFDDTITELYLNASNKGIEWLHPYINRKGEFKYVIIPAEEAIP
                     IWDNKRQNELVAFIRFYFIEDIDGNKIKRVEYYTENEVIYFIEKGNSFVQELLYDEYG
                     KLTEIQEGHFRVNNKEQGWGKVPFIPFKNNEKSVSDLTFYKSLIDIYDNNISTLADNL
                     DEVQEAMYILKEYGGTDLVEFANNIRYYKAIKVGANGGVDKLEINIPVEAKKELLNRL
                     EKNIIIFGQGVNPESQNTGDKSGVALKFLYSLLDLKCSKTEKKFKKAIRELLWFVCEY
                     LKISGSKSYDYKTVQITFNHSMIINEAEKIDMAAKSTGIVSDETIVSNHPWVEDVNDE
                     LERLKKQEDTQKEYDDLIPNNQDGVIDEI"
     gene            38073..39470
                     /locus_tag="PC465_001344"
     CDS             38073..39470
                     /locus_tag="PC465_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HDF2648662.1"
                     /translation="MKYKDYWRKRFEQLEEVQNNKSVKYYLELEKQYKLAMNSIEKDI
                     LAWYNRFAKNEGISLLEAKKLLNTRELEEFKWSVEEYIRHGKENAINQKWMKELENAS
                     ARVHITRLEALKLQIQQQVEVLYGNELDGIDKLMRDIYTSGYYHTAFNVQQGVNVGWS
                     LMSLDTNRINKVISKPWTSDGLNFSERIWGKHRPALINELHTKLTQSIIRGENPKNLV
                     NDFAKSFNVSKSQAKNLIMTESAFFASASRKDCFNDLDVEKYEIIATLDLRTSNICRE
                     LDGKVFDMKDYQVGITAPPFHCRCRTTTAPWFEDEEGYRAAKGEDGKTYYVPSSMKYN
                     EWYEKYVKHNSILEIKNSAIIDSIKEDIKNGKYNLNIHDGKQGKHLKEHNNYIEGRSY
                     LTITKEEAQELVNKHAGNGIIKFNRSGEWDKKELIEVDKNIGVNVNNITGEKTLTNKF
                     KIHYSKTGTHIVPAL"
     gene            39485..39685
                     /locus_tag="PC465_001345"
     CDS             39485..39685
                     /locus_tag="PC465_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648663.1"
                     /translation="MKLWEYVGKNVQITCVDKQIIRGKCDGYTQALDNEPEIASISIA
                     RDGYGIEVYENEIESIENINKE"
     gene            39751..40314
                     /locus_tag="PC465_001346"
     CDS             39751..40314
                     /locus_tag="PC465_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HDF2648664.1"
                     /translation="MDWLKELLEGIKVEDNKIDVASLQKSIEKKIKETTITQEDYTNL
                     ETQLNTANETIKKFEGGMTKEDVENLKTTYETDKKTLEETYKKEIEEKDFNYWLGDAF
                     KSVKCRDEIALKAHLDIEALRNSKDRQKAFEEQINPLKQDKDYLFNATLEGEEPKIDT
                     ITPGQEPKINDFGFNFTGVRPHENNNK"
     gene            40326..41225
                     /locus_tag="PC465_001347"
     CDS             40326..41225
                     /locus_tag="PC465_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009323118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HDF2648665.1"
                     /translation="MAALNYAKEYSNVLAQAYPYTLNFGDLYATPNNGRYRWTGSKTI
                     EIPTISTTGRVDSNRDTIAVAQRNYDNAWEPKVLTNQRKWSTLVHPADINQTNYVASI
                     GNITKVYNEEQKFPEMDAYCISKIYADWTALGNTADTTVLTTANVLEVFDKLMEKMTE
                     ARVPENGRILYVTPVVNTLIKNAKEIQRTVNIKDGGTSLNRQTTDIDTVKIIKVPSNL
                     MKTAYDFTTGWKVGVGAKQIFMSLVHPSAIITPVSYQFSKLDEPTAVTEGKYFYFEES
                     FEDVFILNKKADAIQFVVEGAGV"
     gene            41225..41458
                     /locus_tag="PC465_001348"
     CDS             41225..41458
                     /locus_tag="PC465_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648666.1"
                     /translation="MAQVRKLNRILTIEECKIDDFLEMGYDLIDETGKAVKYGKSLNV
                     KDLIAENNILRSKVESLEEENKQLKEKNKLTKK"
     gene            41468..41869
                     /locus_tag="PC465_001349"
     CDS             41468..41869
                     /locus_tag="PC465_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648667.1"
                     /translation="MENNLIDEIEKRLESFGYILKDGDKWLIDFIREKIENIIKLDCN
                     IKTMPIELKEIEVDMIVGEFLFTKKNMGQLDIESINFEAVEKSISEGDTKVDFAIGSG
                     SQTPEQRFDSLIAYLTTYGKNNILTFRCLRW"
     gene            41863..42210
                     /locus_tag="PC465_001350"
     CDS             41863..42210
                     /locus_tag="PC465_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648668.1"
                     /translation="MVSKTRKAIEMLYRDKCTIVEYQPIKDPVTKRTNNKEVIVLENQ
                     PCKLSYKNIVSATEGKVAKLEQTIKLFISPDIEIKAGSKLIINDKEYVRSGESAIYPN
                     HQEIILELFKDKA"
     gene            42210..42500
                     /locus_tag="PC465_001351"
     CDS             42210..42500
                     /locus_tag="PC465_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HDF2648669.1"
                     /translation="MARWGSVDFREFKRVCKKMEELTKIDLDKFCKDAARELAARLLG
                     KVIRRTPVDTGFLRQGWNGVAYARSLPVYKQGNNYIIEVVNPTEYALTQWGI"
     gene            42610..43416
                     /locus_tag="PC465_001352"
     CDS             42610..43416
                     /locus_tag="PC465_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648670.1"
                     /translation="MAKFLDITGKKFGRLRVIKFSKEIKSGKRNRKYWLCKCDCGNFK
                     EIRTDSLTSGLVQSCGCLKKEQDKLNLTDKYQFKKKYKVQNKRLYSIWKGIISRCTDK
                     NNKRYNRYGERNIIVCDEWFCYDNFANWALSNGYSEKLTIDRINNEGNYESSNCRWVD
                     IKTQCRNRSTNILVKHEEKEITLIELSEKTGISYSCLRSRYSKGLVGNNLIEKVKIIE
                     ESRAKLSIEDVKEIRKKYSDGYTIKQLSEIYPVTYSSISNIVHRRTWKNI"
     gene            43765..44202
                     /locus_tag="PC465_001353"
     CDS             43765..44202
                     /locus_tag="PC465_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648671.1"
                     /translation="MLNNIIDGISIKLDKTFGESYTIYSEDVEQGINEPCFFICPLNP
                     SKTSYPNGRTLKKNSFDVHYFPRSKDKSFEINEVAEMLLEELEYIEIDGDLVRGTNMN
                     FEIIDNVLHFFVDYNYFTIKSNDTEKMNDVELFGGLKRGDNFE"
     gene            44195..44371
                     /locus_tag="PC465_001354"
     CDS             44195..44371
                     /locus_tag="PC465_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648672.1"
                     /translation="MNKTLSKEDDYKFTKEQIVNSKKYVNRKDLLNAILKENELYSFS
                     EVEEIINNFMKGVS"
     gene            44372..45682
                     /locus_tag="PC465_001355"
     CDS             44372..45682
                     /locus_tag="PC465_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HDF2648673.1"
                     /translation="MALGGGTFVTQNKVLPGAYINFVSATRATSSLSDRGIVAMPLEL
                     DWGIDEEIFTVTSDDFEKYSTKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CSIATAKYSGTRGNDLKVIVTTNIDDNTKFDVVTLLDNKKVDTQIAKVITDLQDNDYI
                     TWKKDTTLEASAGLVFTGGTNGESVTGAEYQAFLDKIESYSFNALGSLATTAEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKNDADYEGVVSVENKVKDTGLLESSLVYWTTGAIAGC
                     DINKSNTNKKYDGEFDVDVNYTQIQLEEALKTGKFIFHKVGDEVHVLEDINTFVSFTD
                     DKNDDFSSNQSVRVLDQIANDIATLFNEKYLGKVPNDKAGRISFWNDVVKHHKELENI
                     RAIEDFKTDDVSVELGNDKKTVIVSDAVKVINAMSKLYMTVSVS"
     gene            45699..46169
                     /locus_tag="PC465_001356"
     CDS             45699..46169
                     /locus_tag="PC465_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HDF2648674.1"
                     /translation="MFQQIKARDTISASKAECYVTIEGKRYNFMQAINLEAKMEKNKS
                     EVPILGSTTKGNKSTGSKYTGSATFHYNTSIFRELLYRYKETGEDIYFDIQVTNEDPT
                     SSAGRQTIILKDCNMDSGIIVKFDADGEYLDEDMDFTCEDWELVEKFNIINGME"
     gene            46223..46480
                     /locus_tag="PC465_001357"
     CDS             46223..46480
                     /locus_tag="PC465_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648675.1"
                     /translation="MVKIKDKYKMKDSVSFDYSNKRKIEECVGEMYRKAGLFLVDIAD
                     KLALDTIEGSSLKPITITIKLDENGITTIEKQTKYLVMEVE"
     gene            46482..46922
                     /locus_tag="PC465_001358"
     CDS             46482..46922
                     /locus_tag="PC465_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF2648676.1"
                     /translation="MGDLNAFLSQNAIKVENRKYVASNRFINEEGKAIEWEIRALSSE
                     EDAAIRKNCPKREPILNKKGKHTGQYNTVTDYNKYYEELSIACTVFPDLNDSMLQDSY
                     RVMGANQLLKAMLTPGEYAEYVQEVLDINGFDNSFEDKVEEAKN"
     gene            46922..47116
                     /locus_tag="PC465_001359"
     CDS             46922..47116
                     /locus_tag="PC465_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015390885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648677.1"
                     /translation="MYEGDYDSNIAHYCLHKFKWKPHEYMDLPVDEKAFVAASIDIKV
                     EEEKEEAKKADKDAKRGRRR"
     gene            47184..47975
                     /locus_tag="PC465_001360"
     CDS             47184..47975
                     /locus_tag="PC465_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HDF2648678.1"
                     /translation="MGLFSKKNKKPCCICGSEKGLMPSIEGENFCTACNCKYIDFSEN
                     ILKVTSIMKMMSNSEGMKKFIEVEKKNLKLLEKFTETKSINSSISFDEEQNLLKISYK
                     NRNQILVEKIIKFDDILEFELLEDGETIVKGGLGRAITGGVLFGGTGAVVGGITGKKT
                     SRKVVEIFKIKITVKDINNPIEYINLINSKVKTNSSIYQKAFSDAQEILSILSIITKY
                     NVMEDKKKSISSSTADEILKYKNLLDMEAITQEEFDAKKKELLNL"
     gene            48042..50384
                     /locus_tag="PC465_001361"
     CDS             48042..50384
                     /locus_tag="PC465_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HDF2648679.1"
                     /translation="MATIQTSIRIFDGMTPAFRHMNNAMNIVLSSFEQLQRTSSNAID
                     ANSIRTAREELARAEAGFDRLEQQIRESDNQQRRLNEDINKGASSTDRLVGSAKKLAA
                     TYLGIRTLGGLGNLSDQMTSTNARLSMINDGQLSDGGLNKMIFQSAERSRASYLDTAK
                     IVSRIGMNAGKAFSSTKEIVGFAEQLNKKFVIAGASTEEMNSALLQLTQGLGSGVLRG
                     EELNAVFESAPNIIQSIADYLDVDIGKIRGMASEGMLTADIVKNSLLSAAEQTNAEFE
                     KMPYTLGQIFTSVKNNAVMVFGAIQKKIEDTVSSRGFRTFITDVKDSLYVLGAVGFNV
                     FSGFINLLSSPAFQNFFNVMIVGTSLVVQGLGWIITQALSVANVFSRNWSIISPIILG
                     VVSAISTYIIALGIMQAVTIAGTVANWMSWTSEVIRQRGILGTARALAIGKAEQWGFN
                     AAIYACPIFWIVLGIIAVISAVFILVAVYNHFAGTSISAISLIVGAWYWLCAVVYNVI
                     VGIVNAINICVVEIANIFRTGLYAVQCFFIDMANAGLKAGVNLDKAFDKFATNLANGI
                     IKAVNIAVKGLNWLVQQINKIPGIDLPQMKEFQKVNTVIGTKTTFKPIQKPPEPKAWK
                     PELVEYKNLKSEFIKGYDVGHQLQNKLKDTFDISKIAEDAKKKLGLDDLWDKKYGLGN
                     GFGSAGLNSPLGDAAKGAKDTAGNTAKMAKTMDKSQEDLKYLRDIAEQETINRFTGVN
                     IKIDMNNTNNISKDADVDGIVNVLTEKLNDAMVVSAEGIV"
     gene            50400..51089
                     /locus_tag="PC465_001362"
     CDS             50400..51089
                     /locus_tag="PC465_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDF2648680.1"
                     /translation="MAYDFYLDGVQLPIAPPKLEVKVTNKNKTVDLINVGEVNILKKE
                     GLSEISFEAEFTHNKLPFYRGAFRDVQFFLSKLELLKTDCKPFQFIVSRELGNKVLFN
                     TNIKVSLEEYAISEDAENGSDTKVAIKLKQYRDYSTKKLVLAPPKNETGRPNVKIEPK
                     RVDSVNATNTKTYTVKAGDSLWSICQKQLGNGSLYKKVYELNKSMMDKANKGKNLSKY
                     TIYKGQVLKLG"
     gene            51082..52974
                     /locus_tag="PC465_001363"
     CDS             51082..52974
                     /locus_tag="PC465_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2648681.1"
                     /translation="MVDELVLANDRDVRLVIAHWEDFYEPAVIDGITWEIERRGTPSK
                     LEFTIVMDDILEFCEGNSVRLYYKGVGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELVKMLAKDFNLKYNVIEDTKYKLSRVEENKTLFDMILTALDDTLRE
                     KKEMYTLYDDFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     SGKRDVYIAQDSTHMRSWGILQMFETVDKNMNEAEIKQKCDILLKLYNKKTKSLSLKN
                     ALGDIRVRAGCLVPVFLNLGDIKLQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNTNNKDEKKNGPAQSITKKNTGKKVPAIFTAYYPGNNAMEGGKTDCNGKPL
                     DVKSRTVAGPMNREGVKKTWYTDDFLKKHPVFEYGDKVKIILPGTAYDNKVYTVKDNG
                     GRIYVETNGTYHIDILLANASECKKFGRKNGYIIIGGDEEQTYQVEGNNQSSTNNNSK
                     EDKLISIAKSKLGCNYVYGAEGPNNFDCSGFTQWCYKQIGIKIPRTASAQSKAGKAVD
                     LKDRSKWKAGDLLCRIGGGSNNHVVMYIGNNQIIHSPQTGDVVKIESVNSYRKGKAYT
                     HVRRFI"
     gene            52988..53248
                     /locus_tag="PC465_001364"
     CDS             52988..53248
                     /locus_tag="PC465_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HDF2648682.1"
                     /translation="MSQELLQIIKKTAIDAVETSNPMQIAFGTIESLNPLVVKIEQKL
                     SIGEIFLIQTDTFKRYTDKKIGDKLVLIRMQGGQQYLILDRM"
     gene            53253..53672
                     /locus_tag="PC465_001365"
     CDS             53253..53672
                     /locus_tag="PC465_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HDF2648683.1"
                     /translation="MLPTDNIDYDIEDVSIINFDVRQEPSKTFKLNIEKNRVDGICDD
                     VEALKQTIFLILNTERYEHLIYSRNYGVELNDLIGEPISYVIPELERRITEALIQDDR
                     IENIDNFEFQNIKGKVQCRFSVHTKYGNIKAEKVVSV"
     gene            53673..54722
                     /locus_tag="PC465_001366"
     CDS             53673..54722
                     /locus_tag="PC465_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HDF2648684.1"
                     /translation="MFELMTFENIIKRMLDSVPDTFDKREGSIIYNALAPVAIELTET
                     YIAMDELLDQTFVDTASYYYLEKRCKERGITPLEATNTIAKGVFNIDIPIDSRFNLGE
                     YNYVAIERISEGIYKMKCETAGPIFELGQLIPIEYIDKLETAELTEILINGEDEESED
                     SLRQRYYDSLNSQSFGGNMQNYKDEVNKIQDVGGVKVYPVWDGGGTVKLVIINSNFKV
                     PSEDLVNLVQEEIDPIGHQGQGLGLAPIGHRVTVEGVTSTTINISAEITYKNGYTWEN
                     IKSIAEEAIDDYLNELNMSWEDEENLIVRISQIETRLLSIDGVLDIANTMINEVKSNL
                     TINSNSIVVRGEVVG"
     gene            54715..55332
                     /locus_tag="PC465_001367"
     CDS             54715..55332
                     /locus_tag="PC465_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HDF2648685.1"
                     /translation="MDKEINLINYLPQILQDKEEYIKVFNVGNKEIKILHDKLKDLSN
                     DQFLEDLTISGIKRWEKIMSITPKSNESLEDRRFRIFSKYISKLPYSERFLRNWLDSI
                     VGEGNYELTINNATYNIHLESDARNQDWFEEVHSFVSDIKPCNMTLDYTRVLVSKDNS
                     VYFGATTITGHEITIYPWSPSDIETQGEINILSGNGFGYQEVTIY"
     gene            55348..56373
                     /locus_tag="PC465_001368"
     CDS             55348..56373
                     /locus_tag="PC465_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDF2648686.1"
                     /translation="MATDKSYYTILTDIGKAKIANASIVGEKVDFARIQLGDGGGNEY
                     NPTEEQTALKNVVWEGKVGNVKTDESMTNCLILESLIPASAGGFVVREIGYLDTEGNL
                     LAISKYRSAYKPKVEDGAVIDMKVKTIFVVSNVNNIELKIDPTIIFATLKDLQDLDTK
                     IGTVNTKIDTTKAELTSNIETTKTELNTRIDTENEKQNIKIDQLIAGGSNVASTQTIT
                     IDDWVEDAENGFKATVTHSLLTQRIVVNIIDATTKENVVTNFKIIDDNTIEIRSETRS
                     ELNVYVINGNAETHFINATVDDNRVSEMTTYSSKKIHEEISKVAEQLTGINSNIISSI
                     NNNLIPM"
     gene            56390..57868
                     /locus_tag="PC465_001369"
     CDS             56390..57868
                     /locus_tag="PC465_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648687.1"
                     /translation="MIDFSYETSKRKRKGIYSEQDIFESSHVFYPAGRGRAEAVFELS
                     SVKNISVTRNLNLSKLSSVINGENGVLENLTMEQKLEVLFIDTPKIEIYMDANISKGC
                     EISYRIFDDFASSYPFTVTEKINNEVVSTKVSSKDGKYTTILTDEQILKLEIGSKNTF
                     LIEISTEGGVVTSKQATFTRINNKPTILVNSYNSNSAKFTASDLDNNLSKIEWYLDDV
                     LKETITTDLTAEKTINYELTNNAIHTLKIVATDTENATVEKVLSISKEIMPLQSDATL
                     QDISTKLVEIGEGFKNGKTSIINTLALKNIEANLNNTLVELSEKIKASFDSGDASLQD
                     LMNQLTQANNTITQLNTKYKVASGTTSVIQSSQHVNLYGGLYGATYIRQPYHWININN
                     LGFVPNIFIAENETVSTGSVIEKNIIIATCNMSWSTNKRDFIANLQLTRGKMDDQDFN
                     CHAGFYINNEQDAYINSNGINVPASRTSLPIYGFSWYAIKFK"
     gene            57882..58175
                     /locus_tag="PC465_001370"
     CDS             57882..58175
                     /locus_tag="PC465_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648688.1"
                     /translation="MNRANRIIYDQTGKILLQTGEATGDILEHDTITELHYIDVEYGN
                     IDYSKQYIESINPITKEPILKDIPIYLSEEEKRIQELENQLLIAENEKVGGLL"
     gene            58175..58357
                     /locus_tag="PC465_001371"
     CDS             58175..58357
                     /locus_tag="PC465_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648689.1"
                     /translation="MNINNVVVRILAERILSRGLNPLKNREFELDDVTNTEYRKAVED
                     YIIKQSGVVEGIEPTA"
     gene            58391..59623
                     /locus_tag="PC465_001372"
     CDS             58391..59623
                     /locus_tag="PC465_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648690.1"
                     /translation="MTFKELVNKVRNLVLEAKNVTIEDTENNFTSDNVEDALKEVFQS
                     GVDAKNNVVTALNSKGAEVTTRDTWEEIKNKIDIKEGRLDLRETTLSNNYSYLVTNGA
                     IKYIERCSGNFKTFEYEEPYFYVIKETHLIKINAIDETVVFDITLANANFSCICITQE
                     YLFISDNTKLYKINKSTGSEVQSIEGAYYKLCTYGEFIYGVYGDETSSTLHKIRISDM
                     YIMLTKNLVSNGIYNFKGGKFVCNKNAIYATTEHSNSSSITTCHLSKINFDFAIAKDF
                     RIGGYLHMKNIKFLNDFVIVSDAERGIEIDSNKKSALVKYDANLNLIVYSDDSKYDNF
                     DIYNGYIYAIYSLSSSPFVKISLNTLKHIDSYRKLTETYPNAGMFVINDIVFFISSGI
                     FRNILSKKVYSDEKGESL"
     gene            59620..59919
                     /locus_tag="PC465_001373"
     CDS             59620..59919
                     /locus_tag="PC465_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648691.1"
                     /translation="MIYLGNLMDTEEQNIKYVGMIHYEPNLLSEENLKQGILIESLPT
                     QKYAENKEAKLFINIDTKEVFYRYTDIKSSIEDKVNSTEQTIADLTFQLMSNGVI"
     gene            59920..60057
                     /locus_tag="PC465_001374"
     CDS             59920..60057
                     /locus_tag="PC465_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HDF2648692.1"
                     /translation="MNWYKIITDFYNNGNWTKEQVKTAVEKNKITASEYKEIVGEDYI
                     A"
     gene            60089..60319
                     /locus_tag="PC465_001375"
     CDS             60089..60319
                     /locus_tag="PC465_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HDF2648693.1"
                     /translation="MNEELFEADLKRHETRINKHGEEIDELKIANIESKAELKALCEN
                     LNSLTSMLKWLIGTMITTLVGFFIFAVQRGIF"
     gene            60339..60596
                     /locus_tag="PC465_001376"
     CDS             60339..60596
                     /locus_tag="PC465_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDF2648694.1"
                     /translation="MDNLISFIPEQLLILVAALSIIGKGCKKYKQLDNKYIPVVLLIL
                     GIAFSVWMLGLNPVAVLQGVICWGISIGINQTYKQLKEENK"
     gene            60596..61393
                     /locus_tag="PC465_001377"
     CDS             60596..61393
                     /locus_tag="PC465_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2648695.1"
                     /translation="MKIAIVPGHTLGGKGTGATGYIDEGKENRILTDLIVKWLKQGGA
                     TVYTGKVDKSSNYLAEQCQIANKQDVDLAVQIHFNANKITLNPMGTETIYKTNNGKVY
                     AERVNEKLATVFENRGAKSDVRGLYWLRHTKAPAILIEVCFVDSKADTDYYIRHKDIV
                     AKLIAEGILNKNINNEGVKQMYKHTIVYDGEVDKIPATVVGWGYNDGKILICDIKDYV
                     PGQTQNLYVIGGAACEKIGSMTKEKFTMIKGNDRFDTLYKALDFIDR"
     gene            61643..62134
                     /locus_tag="PC465_001378"
     CDS             61643..62134
                     /locus_tag="PC465_001378"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648696.1"
                     /translation="MAYENGTDFIDYFPDCIEKYKEDNKIFEKAILLLNLYMQKPTWP
                     HCVNEYKSQAEKILGEDPEFIGKYGIQLRKFYDEDENAKVSKEFKNDLYNFSKSTYDI
                     LDNVYFSKSHPFNLSSIYSTSRDDDFIIKIFRYDNNFLELEMSKREVESLINYLSDLL
                     KEE"
     gene            62136..62702
                     /locus_tag="PC465_001379"
     CDS             62136..62702
                     /locus_tag="PC465_001379"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648697.1"
                     /translation="MLGAKKEKEFNLLSFNEKKIEKHKCKNYHNDSSKDKYKYSQSEF
                     IAATLKEADDMNEEERRILEAEKRILETEKRVHQDNKEVKESIDKQFNDIKGIFKEYK
                     NDLDKDRIELKNDLARERAELKSDLKEAINEHKKVTEKDVSEIKNSMKGIEDRIDSTN
                     KWIIGLCITTIIGIATMAITIGISIWPK"
     gene            complement(63112..63300)
                     /locus_tag="PC465_001380"
     CDS             complement(63112..63300)
                     /locus_tag="PC465_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648698.1"
                     /translation="MTKTILCDYCNKGINKDDNKYITFHKKSHMKTNICINCALNLID
                     KDKLNENIINNQHDYSKK"
BASE COUNT        25555 a         6589 c        11386 g        19785 t
ORIGIN      
        1 taaatgtaga taataaattt aatatcaaaa aatgtaacaa aaaggtatgt aagtaaaaag
       61 caaaattaaa atatataata aaaaatatta tatattagat tgaaaagtaa aaataaaaat
      121 agtgaaattt cagaaatatc aataatatta tataataaaa caaaaaaaca ctatatatat
      181 tcgataaaat aaaatttaaa catataatat tttatgtata tattaataaa aggacatatt
      241 gtgttataat ggtatcgtat aaaatcattt acgggggtgg tattaaaatg tttcaatttg
      301 aaacacaaat acacaaatta agacatgatg ttttaactgc aatagctaga cttggaaaag
      361 aagataacct taccagagaa gcaatggata atattcagta tgaaataata aaaggtgaga
      421 aacctacata cagatgctgt gtttataaag aaagagctat aatatctgag agagtaaatg
      481 taagtatggg gttacaacca ggtcaagata agatagattt agatacaatg gatatagaag
      541 aagatgaaca aattatatat attttggaag ctgcatgtga cagttgtcca ataaatgaat
      601 ttacagtaac agatatttgt agaggatgtc tagcacatag atgtaaagaa gcttgtaaat
      661 ttggagctat aacacatgtc ggaggaatgg cctatataaa tcatgaatta tgtaaggctt
      721 gtggaatgtg taaaaaagct tgtcaatatg atgccatctc agaggttgtt agaccatgta
      781 agagtgtttg tccaactaat gccttaggat ttgatagaga aaatatgaaa gctatgatac
      841 atgaggataa atgtttaaac tgtggagcat gtatgtcagc atgtccattt ggagcaatat
      901 ctgataagag tttgatagct cctgtagcta gaaagttagt tcaaaaagag aaaatgtatg
      961 cggtggtagc tccagctata acaggtcaag ttgaagcaaa tgttacatat ggtcaaataa
     1021 aaaatgctat aaaatcacta ggatttgttg atgtattaga agcagcttgt ggagcagatg
     1081 cagttacagt tcatgaaagc ttagaatttg ctgaaagaat ggaaaaggga gaagctttta
     1141 tgacaaattc ttgttgtcca ggatttgttg gttatataga aaaaacatac ccaaatcatg
     1201 taggaaaaat atcttctaca gtgtctccta tgatagctag tggtagattt ataaaaagtc
     1261 atgaaccaga tgctaaagtt gtattcatag gaccatgtac agccaaaaag agtgaggcag
     1321 ctaagaaaga attaaaagga gctgttgatt atgtacttac ttttgaagaa ataatggcat
     1381 tatttgaggc atttgatata gacttggcta agtgttcaaa tgaagatata gatgatgcat
     1441 caatttttgg aagaggtttt ggagctgctg gtggtcttac aaaagctata gaaaattatc
     1501 ttgctgaaaa aggtattggt gttaattttg aacctgtaaa gatttctggt tcaagagaaa
     1561 tcaagaaaac tatgactatg gctaatttag gaaagctaga aggtaatttt atagaaggaa
     1621 tgatgtgtga aggtggttgt ataaatggtt ctggtaaatt cttatcaggt gcaaaggtta
     1681 aagccacttt tgatagaaaa aattctcaat caactaagaa aagtgtctta gcaaatacaa
     1741 agataaaaga ttttagtaat ataaatttag aaaaataaag ataatacaaa gcaacaaaaa
     1801 tacatattgt taatagagtt gttctaagtt gaagtttaac ttttggacaa ctctattttt
     1861 atttatatat ttaattattg aacaacaaaa ataaaaatta tatacactta aaataaaaat
     1921 tacatatata atattttgta tataacttaa caaagtatat gcctatgtta taataattta
     1981 tagaaataaa taaaaaatac aatatacata atagtagaaa tatagcaaaa aggtgtgatt
     2041 tatagggagg attacttatg tttgaatttg aaacgcaact aaaaaggtta aaacatgaag
     2101 ttttaacagc agtagcaaga ctatctattg aagaaaattt aacaaaagaa aatatagaaa
     2161 aaattccata tgaaataatt aaaggagaaa aggcgagata tagatgttgt gtttataaag
     2221 agagagaagt agttcttgaa agggcgcaac ttgcattaag tttaactcca aatagtaaat
     2281 atggagatat aaatccagat tcagttagtt tggacacaga tgagcaaatt atatatatag
     2341 ttgaagcagc atgtgataga tgtccaataa atgaatttac agttacagag ctttgtagag
     2401 ggtgtttggc tcatagatgt aaggaagcat gtaaatttgg ggcaatttct tatataaatg
     2461 ggagagcata tataaatcat gatttatgta aggcttgtgg aatgtgcaaa agttcatgtc
     2521 aatatgatgc tatatcagaa gttgtaagac cttgtaaaag cgtttgtcca acaggagctt
     2581 tggattttaa tagaaacact atgaaagcaa tgatacatga agataattgt ataaattgtg
     2641 gagcatgtat gtcagcatgt ccttttggag caatatctga taagagtttg atagcacctg
     2701 ttgcaaaaaa acttgcaaag aaagaaaata tgtatgcaat agtagctcca gctataacag
     2761 gtcaaataga tagtaatatt acatatggtc agttaaaaaa tgctataaaa tcactgggat
     2821 ttgtagatat gatagaagct tcctgtggag cagatgcagt tacagttcat gaaagcaatg
     2881 aacttattga aagaataaaa tcaggagata attacatgac aaattcatgt tgtccgggat
     2941 tttttaagta tatagagaag atgttcccag atgaaaaaga tagaatatca tctacagtgt
     3001 ctcctatggt agcaacagga agattagtaa aaaaaataga ttctgatgct aaagttgtat
     3061 ttataggtcc atgtacagct aaaaagagtg aggcaacaga gaaaagttta aaagattcag
     3121 tagattatgt acttactttt gaagaactaa tggcattatt tgaagcattt aatatagatt
     3181 tatcaaaatg ttcaaatgaa gatataaatg atggttcgat ttttggaagg ggatttggag
     3241 catctggtgg acttgccaaa tcagtacaga actatattgc tgaaaagggg cttagttttg
     3301 attttgaacc tataaaagta tctggtccaa gacaaattaa aaagacaatg acaatggcta
     3361 aattgggaag attagaaggt aattttatag aaggaatgat gtgtgaagaa ggttgtatta
     3421 atggagcagg taagttttta tcaggtgtaa aagctaaaaa tacttttgat agaaaaaatg
     3481 gacaatctac taaaaagagt gttttatcta atgataagat taaagaattt gaagatgtaa
     3541 atttagaaag ataattgttt tggtacagtc atttttttat tatgccacaa atatgcctaa
     3601 aatttgccct ttttatatgt gtattttaca gagttaaggt tgctatacta taaatatgta
     3661 ataaataaaa tttataggag cttttggatg aggaaaatag tattaaaaga tatcctgttt
     3721 ttagttacta cattatctat aatagtaata ttattgcttg taacaaatat aactactaat
     3781 agtaagataa aatcaacaag tgaatcttat ttaaaaagtg acaaaaatag tgtgaggcaa
     3841 aatggtatcc agaggagcac aaagagtagc acaaaaaata ctgcatttaa gactactata
     3901 ctaaacactg gaaagtctga ttgcatattg gttgagatag gtaacaaagt cataatgatt
     3961 gatacaggag aagataaaaa tggaaaacaa atagtggata ggttaaaaga aaaaggaata
     4021 aatacacttg actatttaat tttaactcat ttagataagg accatatagg tggagtagat
     4081 agtgtgttat ctagtgttaa agtaaagaat attatacaag caaattataa gaaagatagt
     4141 aagcaatatg atgaatatat tgactcactt aaaaaagctg atatagaacc agtgctacta
     4201 aaagataata tgaatattgt aatcaatagt gcagaaataa acatacatcc ggcttcaaaa
     4261 agcaagtacg agagttcaaa tgattattca ataatcacta atataagcta tggagcacat
     4321 aagtttttat ttgcaggaga tgcagaggaa gaaagattgt cagagtttat aaatggaaat
     4381 actttaaaat atgattttgt taaaatgcct catcatggaa gatatgacaa attaactgaa
     4441 acatttttag agtctatttc accccaatat gctgttatta catgttcaga gaaaaaagaa
     4501 ccagaggaag gtgttttaaa aatattggaa agattgaata taaaaacctt tttgacttct
     4561 aatggagagg tagttatcaa tagtgatggt aagacattga gtgtgaatca ataatttttt
     4621 taaaaatatc taaaaaaatt taaaaaaatc attagcaaat attacccctt aaacatagta
     4681 tattttagga gctgaaactc cacatacaaa atgactagga ggtaacatat tatgttggat
     4741 agattttttg gtgaaggcgg atttggtgga tgtgcttggt ggataataat attattcttc
     4801 ttattcttag cattccaaga ttgttgggct gaaatggact tatgtgcatg gatacctttc
     4861 ttaatattat tattaatact ttgtgaatgt ggtgacgttt ttgatggagg atgtggatgc
     4921 taaaaaaatc aatttagatg atttaataaa gcttatggtg ggtataaata aaataccaaa
     4981 ccaatcacaa tctagtgttt gaaggtagtc ggaaatcccc cgctaccttc ttttttttat
     5041 tgttaaaatt tatttttgaa ttatttcatt tacatataat aatttttacg ataaagtctg
     5101 atataattaa aaagaaaata aaatttattt ataggagatg taaaaatggc tatagtggat
     5161 aagattttca atgagataaa acttatggtt gcaagacttt tattgggaaa aaagtacagt
     5221 gaatatgaag aaaaagattt agtgtataat acagaagaag aagttatact tataacttta
     5281 aaaagattag tttttcaggg aaatgtaaac gaagcagaag aaattttatt tgataaagct
     5341 aagagtgtaa atagtgaaaa tatgcagtat atagcaatag aattttatac tatgcttatg
     5401 gaaaagactg atgaagaatt agaagctatg aatttttcta aacaagaagt ttatcaaggt
     5461 atagaagata ttagaaaagt attgaattta gaataaaaga tatatgaaaa tattgaaata
     5521 aattaatgct aaggtgagaa tattatactt atatataaaa atataatatt cttattttat
     5581 tagttatatt taggtatatc ttatttacca taaaactatc ttgaaaaaaa ttaatcttaa
     5641 ttgtataata ttactttgag tgaaaaagta ttaacatttt tttataagat gttttactaa
     5701 aaaaatatat ataaatatac tgttatcaat aagaaattta atttagtgag gtgttaagat
     5761 gaaagtagga tttgaccaca aaaaatattt agaagagcag tctaaatata tcttagaaag
     5821 agtaaataat tttgacaaac tttatttaga gtttggagga aaattgatgg gagaccttca
     5881 tgcaaaaaga gtacttccag gatttgatga aaatgcaaag ataaaagtat tacaacatat
     5941 gaaagaaaaa gttgaagttg taatttgtgt ctatgcagga gatatagaaa gaaacaaaat
     6001 aagaggagac tttggtatca cttatgatat ggaagtttta agattaatag atgatttaag
     6061 aggttatgaa ctagatgtaa atagtgtagt aattactaga tttgaaggac aacctgctac
     6121 aactgtattt ataaataaat tagaacgtag aggaattaaa gtttataagc attatccaac
     6181 aaagggatat ccatcagatg ttgagactat agttagtgat gagggatatg gagcaaatga
     6241 atatatagaa actacaaagc caatagtagt agtcacagca ccaggaccta atagtggaaa
     6301 acttggtact tgtctaagtc agttgtatca tgaaaataaa agaggtaatg tagttggata
     6361 ttctaagttt gagacattcc cagtttggaa tgtacctgta aaacatcctt tgaatatagc
     6421 ttatgaagca gctacagttg atttaaaaga tgtgaatatg atagattcat tccaccttga
     6481 aacgtatggt gaaatgtcag taaactacaa tagagatttg gaattatttc cagtgcttaa
     6541 aaaaataata gaaaagataa ctggaaaaga atcaattttc caatctccaa ctgatatggg
     6601 tgttaataga gttggctttg gaataataga tgatgaagta ataagaaaag cttctataga
     6661 agaaataata agaagatact ttaaaactgc ctgtgagtat aaaaagggac aagttgataa
     6721 aggtgcttat gatagaatga aaatgattat ggaagagctt aacttaaagc cagaagatag
     6781 aaatgttgta ttacctgcta gaaactacag taataaattg aaagaaagtg ccgacaagaa
     6841 tgatacttgt cctgtagttg cattagaatt agaagatggt acaatattaa ctggtaaggg
     6901 ttctgattta atgaatggaa ctgcagcagt agtattaaat gccattaaac atttagccaa
     6961 tatatctgat gatatgcact taatatcacc tgtaatatta gaacctatca taaacttaaa
     7021 aacaaagact ttagctagta gaaatgtttc acttagttgc caagaggtgt taactgcact
     7081 tagtatttgt gctgtaacta atccaactgc acaatttgct atggaaaagt tagcattatt
     7141 aaaagggtgt caagctcatt ctactactat attaaataga gatgatgaac aaacatttag
     7201 aaagcttggt atagatgtaa cttgtgaccc agaatatcct tcacaaaatc tttactatag
     7261 ttaaaattat ataaaaaaat atgggctgtt ttaaagtaat agtttgagca gtccattaca
     7321 attataataa aatcagtagg ctgtcttgta taagacagtc ttttgttttt aaaacatccc
     7381 ataaattaaa tatatatact gttatccata aggaatttta aatttagttc cttggaatac
     7441 ctattgtaaa gcttttatat agtttttgca agtgttttta aggatttttt ataaattata
     7501 ttgaagttaa tggattatag atggttttat ttatggaaaa tatgaatata taaagaaaat
     7561 aatgaaaaaa taccaaaaag aaacataagt ttggtataat taaaaagtaa tataaataaa
     7621 attaatctat ttatacttta aaaggtgata ataatgaaac attatagaaa aataattcat
     7681 atagatatgg acgcttttta tgcatctata gaacaaagag ataataaaaa attaaaagga
     7741 agacctgtta ttgtcggtgg aaatccacaa agccgaggtg tggttgcaac gtgttcttat
     7801 gaagctagaa aatttggtat ccattcagct atgccatcag ctgtagctta caataggtgt
     7861 ccatatgcag tttttgtaag acctcgattt gatgtttata agagtgtgtc agagcaaata
     7921 agagatatat tttatagata cacggattta gttgaaccat tatctttaga tgaagcttac
     7981 ttagatgtaa caaaaaataa aaaaaatatt gattcatcaa ttgagatagc aaagcaaata
     8041 aaaaaagata tatttagaga agttggtctt acttcttcag ctggtgtgtc atacaataag
     8101 tttcttgcta agattgcatc agacttaaga aagccaaatg ggttaactgt aataaccgaa
     8161 gaaaatgccc aggacttttt agataaatta cctgtgaata aattttttgg tgttggaaaa
     8221 gttacttcaa atactcttaa aaatttaggt ataaaaactg gatatgattt aaggtgttta
     8281 aatttatttg aacttgaaaa tatattcaaa aaaagaggtt atgaattata taaatttgct
     8341 agaggaatag acgatagacc agtggaacca aatagggtta gaaaatctgt tggggctgag
     8401 actacattaa gtcataattt ggatattgat gaagaagaaa cacgcaacat tcttgatgaa
     8461 ctttgtgaag aagtatgtca tagattaaaa aactctgaga agtttggaaa aacattaaca
     8521 ttaaaaatta aatatgagga ctttacaaag ataactagaa gccttagttt agaacactat
     8581 attgacgaat ataatgatat aagaagtggt gtagataatt tgttgagaaa tgttgaggtt
     8641 aatggaaaac aaattaggct attgggagtt acaatatcaa acctaagtga taaaaaagaa
     8701 acttataaag atattacatt atttgaatac atggatagta tccaaatgtg agttttgttt
     8761 aaatgaaata acactagctt taatactata taattgaggc tagtgttatt ttatgaatat
     8821 ttttatattt tttgtttttt gacattatat attatatact atatataaat actttatatt
     8881 tgtagcaata ttcagacaaa tagtgaccta aaaatcgtac tttgtttaca taaataaaat
     8941 agtatgatat aattataaaa acaacttata atattgaaga aggttgcttg ttcgaaaaag
     9001 gggatgataa attatgatag agataagaaa tgtaacaaaa aaaataggaa ataatgttat
     9061 attagatgat atttctctag ctgtagaaac aggtacattg gtagttttga ttggttcaag
     9121 tggttgtgga aagactacta ctttgaagct tataaacaaa ttaataaaac ctacatctgg
     9181 tgagatatat attaatggca aaccaatttc tcaggaaaat gaaatagagc ttagaagaaa
     9241 aataggatat gttatacaga acacaggcct attccctcat cttacaataa aagaaaatat
     9301 agagctaatt ccacgcctaa aaaaggaaaa atccgttgaa gaaattgaaa aaagaacgtt
     9361 gcaactactt gagatggtag gacttgatag tgatgaattt ttgaataagt atccttcaga
     9421 acttagtggt ggacagcaac aaagaatcgg tgttgcaaga gccattgcta ctgatgctga
     9481 aataatattg atggatgagc cttttagtgc tttagaccca ataacgagaa catctttaca
     9541 agaacaatta ttttctcttc aagatgaatt gaaaaaaact ataatatttg taacgcatga
     9601 tatggatgag gctttaaaga tagctgataa aatttgtatt atgaaggatg gaagaatagc
     9661 acaatatgat actcccgaaa atatacttag aaagcctgca aatgactttg taaaagattt
     9721 tatcggagaa gatagagttt gggataatcc agaatatata aaagcaagag atattatgat
     9781 aaaaaatcct attgctgtta attctactag aactgtaact caaggaatag aaattatgag
     9841 aacgagtaag gttgatagct tactaattat agatagagca aaaacattaa aaggtattgt
     9901 tactgtaaaa gatatgaaag atattgatga taagtcaata ttacttgctg atattatgtc
     9961 aagtgagcct ttgcatgtaa atgaaggtga taatttagta gaaatactaa atgtaatgaa
    10021 tcgtaattcg gttggatata ttccggttat ttctgatgaa aataaactgg tagggcttat
    10081 tactagaagt agtttacttt ctgttttaag tgaacaattc ttagaaatgg aggtgagtgt
    10141 tcttggctaa tttttttaac tttatactat tacaaaaaga taagattata gagcttttaa
    10201 tacaacatat gagtctaact gttacatcta ttttaatagc tataatagtt ggtgttcctc
    10261 ttggaataat tatttcaaga atctcatctc ttagaaagtt tgtacttgga tttgtaaact
    10321 tagtccaagc agttccgtct atggcacttt tgggtcttct tgtacctata cttggtatag
    10381 gaagtaaacc agccatattt atggtagtgg tttattcatt actaccaatt gtaaaaaata
    10441 cgtatatagg tataacaagt attgacccag tagtattaga atcagctaaa ggtattggtc
    10501 ttacaagaaa tcagacatta tttaaaatac aattcccttt agcacttcct ataataatgg
    10561 gtggagttag aatatctgca gttacagctg ttggtttgat gactcttgca gcatttatag
    10621 gtgctggtgg tttaggatat ttagtatttt caggggttca aactgtaaat aataatatga
    10681 ttttagcagg ggcaatccca tcatgtataa ttgcactgtt agttgattat ttatttagta
    10741 aaattgaagt tgcagttact ccaaaaggat taaatccaaa agcacctaag aagaattata
    10801 tagcacttaa agtaatatct gtagtggttg ttgtttcaat gttgttcgtt gtttttagtt
    10861 ctagtttttc aagtaaaaaa gatacaataa ctattggttc taaagattat acagaacaac
    10921 ttatacttgg caatgtttat gctgaattag tagaaaaaaa tacgaatctt aaagttaaga
    10981 agaatttaaa tctaggtggt tcatctgttg catttaatgc aattaaatct ggtgagttag
    11041 acatgtatgt tgactataca ggtacacttt tggtaaatgt aatgagacat gctccgatta
    11101 aagatgctga tgaagcatat aatgttgtaa aagatactat ggaaaaagaa aatcagttaa
    11161 ctttacttga ccctcttgga tttaataata cttacacatt agccatgatg cctgaaactg
    11221 ctgaaaagta tggaataaat actatttctg atttgactaa atatggtaaa gaatttacat
    11281 tctcaccaac tttggagttt gaaaatagag aagatggtct tgtagggctt tctagagatt
    11341 atggtttaaa attcaaagat gtaaaagcaa tgaatggaag tttaagatat acagctttag
    11401 ataataatga atctcaggtt atagatgcat ttttaactga tggtcttatt aaaaagttta
    11461 atcttaagat attagaggac gataaaaatt tctttgtacc atattatgca gcaccattag
    11521 taagagaaga tactttgaag aaatatcctg agttagaaaa agttatgaat atgctttcag
    11581 gaaaaataaa tgaagaaact atgagagaac ttaattatca agtggatgaa cttggtaaat
    11641 caccagaaga agttgctcat tcattcttag ttaaagaagg cttagtataa aaaattaata
    11701 gtttatatca aaaatttaag ggagtgtctc aaaatgaact ttttagttca tgaggcactc
    11761 ttttttatat gaaatcaaat atattttatc atttcaacaa taaaaaagaa gattatcttt
    11821 attttgagac agtctcttat ttttatgtat accaaaacca tacctacgat ttttatttat
    11881 aattaagttt caaatagaat gaacaagtac aaccaatttt gaatataaat atagtaaatg
    11941 tgcttatata cgattttatt gtctggttga ttgatattga tagatagctt tctttattga
    12001 atcgaaggga gggggaattt gttatggata actataagaa agtgaagcaa gtattgtgga
    12061 taattttatt tgctaatttt gcagtagcat tattaaaaat cattattggt aatcaaataa
    12121 aaagctatag tatgacagca gacggatttc attctttgtc agatggagca tctaatatag
    12181 tggggcttat aggtattttc tttgcatcta aaccaaaaga taaaaatcat ccttatggac
    12241 ataaaaagtt tgaaattata accagtttat ttataagtgg tatgttgttt gttatagcaa
    12301 ttaagataat tcttagtgca gtgttaagaa tagctaatcc agttgtacct gctataacta
    12361 tagaaagttt aattgcttta attattacac tttttataaa tatttttgta tgcatgtatg
    12421 aatatagaat tgggactaaa ctaaatagtt atgttttgat ttcggattca ttgcatacaa
    12481 gaagtgatat atttgtgtct ctaggtgtat tggttacttt agttggtgtt aagttaggat
    12541 ttccagtaat aatagaatct atagttccta ttattatttc tgcattcata atttattcgg
    12601 cttatggaat atttaggcca tctattggaa ttttggtcga tagagtggct gtagatgagg
    12661 attatataaa agaaattgtg tttgaattta atgaggtaag ggatgttcac aatatcagaa
    12721 gtagaggtag caaaagttct atttatattg acatgcatgt aatggtagac ccatttataa
    12781 gcgtagagca atctcatgat ttaacacata aaattgagaa acaaatacaa gaagaaatta
    12841 atgaaaatgc tcaagtaata gtccatattg aaccttttta tagtttttaa cttagttata
    12901 aaatacaagt tataaaaaaa tataatttat aaaaaaaata ttataccata aataatttat
    12961 aaaaattatt tatggtataa tattttctat aaagaaatta agtcttaata tatctaagga
    13021 ggaatttaca atgagatacg ttgaatatgg aaagacaggg aaaatggttt cagtagttgg
    13081 ctatggagga ttaaggtttg atttagaaaa aagtaatcaa gaaaatgctg atttagtcaa
    13141 atatgcgtat gaaaaaggta ttaattactt tgatacagca ccagggtatt gtgatgacag
    13201 aagtgaagat atatttggac tagcctttag acaaatgata aaggaaggta agaccgattt
    13261 ttatgtatca actaaagaaa agccaaaagc atgtgataca tcagaaaaag ctatagaggc
    13321 tgtaaaaaaa tcaatagaac gattaggcgt atctaaaata aatttttatc atgtttggaa
    13381 tattagaaag atggaacatt acgaactagc aatgagacct ggaggtcaat atgaaggatt
    13441 attgaaatgt aaagaagaag gattgataga ccatatagta ttttcatctc atcaaccagg
    13501 agatgaggtt atagatattc taagtgaaaa taagtttgaa ggtgtaacta tgggaataaa
    13561 tatattaaac tttccatata ggctaaaagg tgccaaatat gctgttgata atggatatgg
    13621 tgttgtggca atgaatccat taagtggtgg aactattcca aagtataata ataaatactt
    13681 ataaataagt ataaataaat gttaaaacgt gtagttttag cgatatttaa aagaaattat
    13741 tataaattaa ctgactgaca tttaactgac aaaacctatt tttttaggtt caactgacat
    13801 ttaactgaca gccagtaatc atttatttga ataatatttt acttaaatta tcagatgctt
    13861 ttttatccat ttcttctaaa acatgagagt atctgttcat agttatttgt atatctgtat
    13921 gacctaacct ttctgaaaca actttcatgt tagtacctcc taataaaagc aaacttgcat
    13981 ttgtatgtct taaatcatgc atcctaatgt tttttaagtt atttttttta ataaatctat
    14041 gaaaagactt tcttaatgta gctggtaaaa atggattata atctttgttt aaacaaacta
    14101 aattattttc atttttaagt attccttgta attttaattt attttgtctt aatttttcaa
    14161 tcttaagttt ttctattagt tcatcaggag ctgacaatgt tcttcttgat tttgatgttt
    14221 taggttcttt aaattctatt ttattattag cgtatataag tgtttgactt acacttacag
    14281 agccgatatt taaatcaaca tcagtccatc taagtccagt agcttctcct agtcgcaaac
    14341 ctaatgtcaa cattagtaaa ataggtattt ctatgttact attatttagt ttttctatca
    14401 acaataaagc ttcttctcta ttatatattt caatcttaga agaattttct ttatgaggaa
    14461 gttttacaaa atcacatgga ttttcattta tttctcttaa tctatatgct tctttcagaa
    14521 cagaacttat aaaacgatac cttatctttg agctactaaa agtacaatta ttaaaagttg
    14581 tatttataaa agtttgaatt aaaacaggat ttatatctat aagttttgta tctttaaaaa
    14641 aaggttctat ataattctta acccaagatt tcctatttat aactgtataa ggagaccaat
    14701 ttttttcatt tgacattatg tatttataac acctctctac aagagtggtt ttacttggag
    14761 taataaactt attactattt atagtagatt ttatttcaat taaatgtttt tcagcatcct
    14821 ttttcttttc atagctccca taacttttct gttttatctt gccagtcatt tcttctatgt
    14881 actccacata tacatgaaat ttttcccctc tttttcttat aaaagctgat ttgatattca
    14941 tatgtacact ccctttataa gtattattca tgtttaaaat atattgaata gctcttgttt
    15001 tattatatca aatctaagtt ataaatacta ttcgataata gatagatgta tacagagata
    15061 tatggatgaa taaaaaagta atatataggt aaaatatgta agaattatat gatataataa
    15121 ttgtagcaag gaaaataaaa ttgaaaagct aagggtgatt ttctcatata aacgccaaat
    15181 tccaatatag gaaggaggtg aatttatatg ttaattaact ttttattgag tatagtagct
    15241 ggaattgtgt cagcttacat ttacgagaaa ataaaaaatc acccaaacgc caataagggt
    15301 gatttaaaga aataactttt aaattctaat caattagaga aattcacctt ttacaaagta
    15361 aattttatct ccttgctatt attatatcac aaatttgtac agatattcaa aaataatatt
    15421 ttattaaatt ataattgttt gaatatattt aagctaattt cttatttaat tcttgtattt
    15481 ttaacgtttg tctatattct tgtgcttctg ccaattttgt atattccaca gtcttatcga
    15541 aatttttctc aacttctgtt cttatttcat caagcgtaac tttgaagaat tcttttctat
    15601 tatttacctt gttaactctc ttattatcaa aagctttatg taaagctgat tctaatttag
    15661 gtgcatcttc actaaatata gtcgcatgta tatcatattt aaaaggaact gatgcactac
    15721 ttaattcatt tattctctca gttgggtcta atcttctagt tactcctatt ttatatatat
    15781 tttctccaaa actaccaata ttggagatta tgtatacatg tcctgctctt gtattttgtt
    15841 ctctatttaa tacatcatct aaatcttttg atagtaaagc tagtttttct tctatagaat
    15901 tgattttttg ttcccattct aatttgtcgt tttcatcttc tggtatagtt gattttagtc
    15961 taagtaattc attcttaaat tgtaattctt ctttttttag ttttcttttt tgattttcta
    16021 tttctttttg aacaagagct tcttctttca tttgttctct caaagctctt tgttcttctt
    16081 tttcttcttc tttcatttga aggtattcat aatataaata aagctcatct attttcaaat
    16141 taagatagtt ttcttttata gaaactttat ttgaagtatt taatttattt gtatcagtaa
    16201 atgcttttcg tattcttttt tctatagaat caatattttt aaaactaact tttgacatag
    16261 caatgtcaca ctcactattg aagagcttaa gagctgtttt aatattttga ttagtcatag
    16321 ttctaccttt ttgaatactt ccatcaacag tccaagaatc agaatatttt acacctgttt
    16381 tatttcttat taatagtttt tgtctttctc ttatttcttt taatttttcc atatactcat
    16441 cggaattttc aaaatcatat tttggattat ataatccaaa tgattgaagt agaacctcat
    16501 cttcagtctg tattaattcc tcagatagcc tttttaactc ttctttttta ttttttaaag
    16561 ttgtatttat atctctaagt tcttccctct cgtcttttaa ttcttctaaa tgagcgttta
    16621 aagtattaat attatcctta agtatatttt tatcctttat aagattatca agtctttctt
    16681 tttctatttt tagttcttcg ataagtttaa atttatcttg gttttctgaa tcaaatttat
    16741 caatttcaac tttctttttg tctaatagat tggataattc ttttaactta ttttcatttg
    16801 attcacataa atcttcaaag tgtttttctt tcattttaat ttcatcattt aataaaatat
    16861 atttattatt gattttttcg acatcagata atagtatact aatgctatct ttatgttttt
    16921 tcattatctt atttctttta aataagaata ttattgcaac tataaatgat atagagtatg
    16981 ttgaaaacgt agaaagaatt agtatggata tagtccataa agaataatac cagggtatct
    17041 tgaaattaag atttttgatt ttttcatcgt tgatgagtaa atcacttttt aactgttcat
    17101 tttcattgtt catatcaaaa ctcctttttt attttttgtt ctactttatg ataataataa
    17161 tttaagtata taaaatttta tgtgcaattt ccatatattt gcaaaaaaag gtaaaaataa
    17221 aacaaaatgg tagttattta aaagaattta gttggattat aaaggtatgt taacagaaat
    17281 tagaaaaata atataacatt cttataaaag tatgttatca gtattttgag cataaggaaa
    17341 agccacttaa aattagtttt aatcatttta agtagctctt ttattatttt agatactcct
    17401 ttgaatattt aatccaagca tcaataccat cgattaagtg aattaattcg ccataaatat
    17461 gttctgaacc aaattcattt ttcatgtaca ttatccattt ttttctacct tgcaatttaa
    17521 ctttaccaat gaagttgtct gaagtatcaa atacattaaa tgctccatct gacattctat
    17581 caaagacaaa attatttttt aattcatttt cgtacatttt aattttaagt atattaaaaa
    17641 agtagatttc attttcatta attttgaagt tgtaattttt attattaact tcgaatggta
    17701 ttgatttgtt atttttaaca atatccatat aatgtaaatt tttattatta atactatcat
    17761 ttgcgttata tgttatagta gagtgattgt atattacatc atttatacta tttatagcat
    17821 tattaatttc gatattatca attttttctc ctgccaaacg ttttactaat atagaagttt
    17881 tggagttatt tcctaacata tcacaaagta tataggatga tttaattatg ttatctaaaa
    17941 gtgtgtcttt taaatttata tctaattcct ttatggcttt gtaagactca attttcatag
    18001 gtgtaatttt atgattttcc cagtttatat taattcctct ttggatattt ttagaggatt
    18061 catatttaca aattaagtca tatgcttcct catatttatc aatataaatt aattctaaac
    18121 actggtcttc taggtcagta tttttagtaa cagatttacg cacatctttc aacagttctt
    18181 ttcctttatc tgttaaagca taatatttgt tggagctatt aaaaaaatta gataaatctt
    18241 tgcatgagat ttctttttct atcctttcta ttaattcagc ctttttacca gttgatttaa
    18301 tattattaga ttttaatatt tctttcaatt ccgaaactgt taacttagta aggtcttcaa
    18361 tgtaatttga aatcttaaga taatccatgt tgaaaaactt agaaattaaa tatgaatagt
    18421 taatattata ttcatatgtc caataggttg ctatataagg ctcgtatata ttttctccaa
    18481 ttatgtattt taggaaagat ttttctattg atgtaagtgg tttagtatct gtttctaata
    18541 tattgttttg tgggttaaac ttattaatac tattagtatg tatatcatat aaagcatctg
    18601 atttttctct tgcttgtttt tctaattcat ataaatttgt tgtatcatta caacttacat
    18661 tcagcacttt attaatttca ttttttactt ctatgttatg aggtgaatta gaattacatt
    18721 ctagtgaaag tgtagtacta tcattatagc tttgttttga ttcgttcgat ttttcattgc
    18781 aatcaacatt atttttgttt ttattttttc taaatagatt caaaatgctc ataaaaaatt
    18841 actccttttg tatttaatta atttctagtg tattctactt tgtgacaata acaatttaag
    18901 tatataaaac tttctgtata aatgctatgt atattaggaa aaaacataga attaaatagt
    18961 tttgaaaaga atactatatt tatatggtat aaaaagtaaa acgaagattt taaaattaaa
    19021 taataaaaaa tattatataa acaagaaaat acaaaaaatt ataattaaaa agacgattaa
    19081 taatacacag gaatggaaaa aataaccaag actctacaaa attcgatttt tttgttacaa
    19141 ttcccctttt tttattgcat atatttaaca aaagtattat tatgtaagta agataattat
    19201 ccaagaaaat tttgaataat ctaaaaatat ttttagaaat gaaaatacat agttatattt
    19261 tattaaaatt cattagggaa ttttgactaa aaataagaac gtaagttctg atagtagggg
    19321 gaaggcgtgt ggaaaaatca aaaaaactac taattgacac aggggataca ttgaacaaat
    19381 taagagaaaa taatagtgag aagttagaaa agtacataga attattaaaa gaatattata
    19441 aacaagaaaa taaaaaagaa agagaatagt tttcttctct ttcttatttt ttctcattaa
    19501 gttcttcttc aagaaatact tttgctattt tgaacatttt ttcttgacta gaaggactta
    19561 attcgctaat tagttttaaa gcttctttta tatcatcaga gaaatttaga ttttcaatta
    19621 gctctaactc actaagattg tctatatttt ttacattgac ctttccaagc aaataatctg
    19681 tagatacatt aaaaaaatct gataatttta aaattatgtc atgtggagga aatctttctt
    19741 ccttctcata aaaagaaatc attttaggag taagacctaa aaaagttgca agttcttttt
    19801 gagtaatatc tttttctttt cttaattcct ttattctata tccaatcatg ttatttagcc
    19861 acctttttaa tttatattga actattagtt cttaattatc aattatagct catttttttt
    19921 aaaaaagcta ttgacaatgt actaatagta ctgtactatt agtacataag ataaagtaaa
    19981 agaaggtgaa aaaatgaata aactaaaaga ttttagaata caaaaaggac taagtagaaa
    20041 tcagttagga gctgaattag gtcttacaag taggtatata gctttcttag agaatggcga
    20101 aagagtaccg tctctaaata cagctgtaaa aatagcagct tatttcaata cttcaataga
    20161 gtatattttt ttgaaaaaca actgtactaa aagtacattt aaagaaaaag gagctgaaaa
    20221 atatgaataa cttacaagta atagaaagaa ataacgaaag agttttaact acacagcaac
    20281 tagcagatgt atatgaaaca gatgcaagaa atataagcaa caattttaac aataacaaag
    20341 atagatttat tgaaggtaaa cattattttt tattgcaagg tgatgattta aaaaatttta
    20401 aaggtattca tacagaatat gaaaacctaa aatttacttc aaaaatgtat ctttggactg
    20461 aaagaggagc aaatagacac tgcaaaatat tggatactga caaagcttgg gagcagtttg
    20521 ataacttaga agaaacatat ttcaaagtta agcaacataa gccaacttgt atagaagatg
    20581 tattaataga aagtttaaaa gaaatgaaag atttaagact tcaagttaat caagcaaata
    20641 gcattgcttt agaagcaaag acagaggttg aaacaataaa agatgtagtt tcattagact
    20701 caaatagttg gagaacaaat acacatcaac taattgcaag aatagcaaaa aaacaaggtg
    20761 gttttgaaca tataaatatg cttagaacag aaagttatga attattaaat aagagatttg
    20821 gagttgacct acatagaaga ttaatcaata aaagaagaaa aatggcagaa gaaggtgtat
    20881 ctgaatctaa aagagagaaa gttaacaatt tagatgtaat acaagatgat aagaagctaa
    20941 tagaggggta tgtggctatt gtaaaagata tggctttaaa atatggaata tcaagtgatt
    21001 taagcaaaaa ttaggttaaa tcatgacagt accttgaaaa ctaaatacag gatattcaat
    21061 taatatgaga aggaggtttg aaaatgagtg tagcattaca attcatagac acaaaagact
    21121 tagtacaaga gttaatgcga agagatgata caacagacat catcaagatg tttttaggta
    21181 gagaaggaat taaaagaatg gagttaatga ctatagaaga attttgtgag tacttgaaaa
    21241 tatctgatgt aacagctaga aacatggcaa gagaagccat gataacaaaa gattttattg
    21301 ctttaaaaat aggaagaaag tacatgattg atagaatatc atttgaagaa tttattatga
    21361 aaaatgcaat gaaagataga gatgtaatga aaaaaagaaa gggggtgatt taattgactc
    21421 taagatggtt tttaagattt tgtaaaaaac ataagaaagt gcctacacca cgattttatg
    21481 cagagtgtgt agcttatatg gaagaatgta aacaaagagg acttgaactt taagggggat
    21541 tgaatatgga agtaactaaa agatttttag aatataaaat acaggctcta agcgagagga
    21601 tagaatttaa aaaaaacaat tggatataag tgtatagcag atgaaaaaga actaggagca
    21661 tatgaggata ttttgcttat gttaaattca gaaattgaat caataggagg agtggaaaat
    21721 gaagagtaga caagaattaa tcaaagatat agaaaaatac agaaaagcac aatacttaat
    21781 atatttagat atagtacaaa gagcatgggc agatagaagc cttacagcag atgaacaaga
    21841 cagaattaaa caagaagcat atgcagagta caaaaggata gaaagagata cagaagaagc
    21901 agaagaactg ctaatgagag aagaatttga aacagataga cccttagcag ttcaaataat
    21961 gtagaaaaga gccactgcaa tggctctaat caaaaacaaa aaataaattt aataattata
    22021 tattatagca taaatggagg gaaattatga gtactttata tgaattagct acagatttat
    22081 tagaaataga agaaggttta acagaaataa caggaaatga aactgaaaaa ctagaggaaa
    22141 taaaagaaat aataaaacaa gagatacaaa ataaaaacac taggatagtt tcagtaatat
    22201 taaacattga cagtgatata aactctatag attcagagat taaaagattg caagagttaa
    22261 aaagggtcaa aaagaatact cttgatagat taaaaagcaa tataaaagac tgtatggaat
    22321 tacttggtac taaaaaagta gaaacagttt taggaaatat aagtataaga aagtcagcag
    22381 gtagcttagt catagaagat gaagaaaaga tacctgctat atataaaaca gtagagcaag
    22441 ttgtaaaagt agataagaac actattaaag attttattaa aaaaggtcat gaggttgaag
    22501 gttgcaggat tgaatatgga actacactaa caattccaaa agctaaaaaa gagtaggtga
    22561 ggaccatgga aattaataat atttacatta aattgatgga tgtaagagtt aaatttagta
    22621 agttgaatct aaagaaaagt ggagaaaata agttcgctaa cttcaagtat tttgagttag
    22681 cagactttct accacaagca actggattac ttgaagaagc taagctatgc cctatagtga
    22741 cctttacaaa tgaatatgca actctaacat taattaatgg ggaaaaccca tcagagcaga
    22801 ttatattcac ttctccaatg cgagacttac aacttaaagg ctctaatgaa ttacaagcac
    22861 taggaggtat agaaacctat caaactagat atttgtacat tcagttactc aacataactg
    22921 aaagtgacac ttttgacgca actagtggca aaaatgaagc taaaagtaat tctaacaata
    22981 gaattttaac agataaacaa ttaagtaggt tatatgcaat agcaagtaat gcaaatgttg
    23041 ataaagaaag tttgaaagaa aaagtattta aaagatttgg aaaagagata aaagatttaa
    23101 caaaacaaga gtatgacact atttgtaatg cttatgaaaa taagcaataa gggcaggtga
    23161 tattgtgggg attataagag taagcaaaga caaagataat ccatatgtag ttttaaataa
    23221 aacttgtttg gaagatgtga aattaagctg gcaagcaaaa ggtttacatt catatctgat
    23281 tagtaagccc gaccactgga aaatctatgt taatgattta tataaaagaa gtaaaaatgg
    23341 gagggatgct acagcaaata ttttaaggga gctcatagaa aatggatata taacaagaac
    23401 accttgtcga gattctaata ctaataagat gcttggagga tatgattatc aagtatatga
    23461 gataccactt gaaaatcctc agaagctaaa atcccgaaaa actgatttcc cggaaaccgg
    23521 atttcccgga aaccgggttt ctcggaaacc ggaaaacacg gaagtagtaa gtaatgactt
    23581 taaagtaaat aatgatatta ctactattgt tattaatgaa caatccaata aagacaaaac
    23641 cacctacata aaaaaatact ttgaaaaata tataggtgtg attactccta ataactttat
    23701 agagttaatg agttacttag atgatggaat ggaagctgat gtaattataa gagctattga
    23761 tgaagcaata gcaaatggag ttaagaatta taagtatgta aagacaatat taaataattg
    23821 gatagaagca ggtgtaaaaa ctaatttaga acttacagag tatcaaaatg agtttgagag
    23881 gaagaaaaag agtaaacagg agaagaaaca gtctaataat aaagctgtga atactcataa
    23941 tgtgaataaa aataagtttg ctaactttaa tcagactttc actcaatatg aagaaaaaga
    24001 gctagatgag attattaaaa agagtcagaa ggaaaaattt aaataaaatt aaacttctag
    24061 gaagtaaata tcaatatatt gcttcctgga aaggggaggt ataaatggcg agaatatatg
    24121 cacaaagaag tggttcttta aatgaacaag atagattgga attattaaga ttacttggga
    24181 aagctggata tacagtaaag attgctagag agaagcaaaa tagcaagaca acttatactt
    24241 actttgttga gtatacagaa gagcaggaag aaaaatagaa ggggactagt taaatgaata
    24301 caataacttt agttggaaga ttagttgcag atgcagaatt gaagtacctt ccaaattcgg
    24361 gtactccaaa aataaccttt tcaatggcag tagatagaag gtttaaagat aaaaatggaa
    24421 ataaaataac tgattttatt caatgtgagc aattaggaaa acatgtagag aatctagtgc
    24481 aatatcttgt taaagctaag cctatatatg ctgttggaga gttaaatata tataattaca
    24541 aagatgaaaa tggttgctgg aaatctatta ctaaggttaa tgtaaatgct ttagaactac
    24601 tttctagtaa aaatgataat aatgctaaac aagaatatgt accaccagga ctggacccac
    24661 aaggttttca agcaatagat gatgacgata taccttttta attaagttaa atagtctagg
    24721 gagtaactat acaatattac ttcctaggag ttaaaaatgg agggataaaa tgagatttga
    24781 gataggtaaa acttataagt ttgatagaga gaaatttata gcatgcaatg gtatagaaca
    24841 ctataaaaga tgtgaagaac tttggattga agatgttgaa gatgttgaat ttactgttaa
    24901 gaaaatcttc gatgatggat atatttgtta tccaaaagaa ttttggttta attttggtgt
    24961 agtttcggaa tggtgtgttg aagttaaata aggtaggagg aattagatat ggctaaaatt
    25021 tgggtagatg caggaacgtt tttagaaaaa actattgata tagaagatat gtttgagctt
    25081 aatttaagaa aagtaagaaa gagaaatgaa aaaataaaaa atgaaattga gaaaaaaata
    25141 aaagatgaag attcagaaat aaaaattaca aatcgtggtg gaccaggaaa gtctataaaa
    25201 gttttcaata taaataccag agaggtcaag attcttaaga gtgctaaaga agcaagtaaa
    25261 tatataaaag ttagttgcag tcatgccagc tatttagcta gggaaaataa atcaactgag
    25321 gatggttgga aagtagaata tattcaagag gtgtcagatg gtattagcaa atgtggaaca
    25381 agtaattaag ttagctgaaa agatattaaa taagaaaaag tgttctgtta ataaagctat
    25441 tgatatagct ataaaaatat taagtaaata tgagtgcgag gggatgttaa gaaatgagtc
    25501 taattgaata tagaggttat gattttgaaa ataaaaagtg gatttattct aaaacaataa
    25561 tgtggagtaa tgctgtagac tgtttattaa tgttgaaaga agattttaaa tggcaaaaag
    25621 tttgtaatgt tggaatatgt tctgaagaat gggctgcaaa taatcaagaa atttttgaag
    25681 gggatatatt aaaagaaaat tataatcctc gcaatagaag ttcatatgga attgtaaaaa
    25741 gagattttaa tagtattaag ttatatttgg aatggcatta tttaaagaag cttgaaggag
    25801 aatggataga gcttataaat aaaacagaaa tatatcatag tagagattac aaaatagttg
    25861 gtaatgaatt tgataattta gaggaagtca gagcagagtt cttagaacgt aaggagagtc
    25921 ttgaaaatga atatcttagc tagtgcgata ttagtaatag gaagttttat agctggtagg
    25981 gtttatgagt atagattgaa tctgaaagag tgtgaaaatt gcgataatat gagagggctt
    26041 aagaatgaat gatagattag aaatgataaa tgcttctgta aattatatac agatgatatg
    26101 tgaaagttca aatatagcta ttatagcaga gcgaggaaga gttagaatat tagatttaga
    26161 aactaaagaa aaatatgatt tattaaaaaa taaactcgag gaaatgttag aagaaatata
    26221 agtgaaaata tctaattaaa acagtttaga gagttgcaaa atgtcttttg gtataaatta
    26281 ttgttgaagt gttttgtgac tctcaaaaat gaaaatagag aggggaataa tataatggat
    26341 ttaaataaaa ttatgaatga tgcactagta gagttagagg aaaatggttt tgtagaggaa
    26401 gtagttaaaa aacaattggc agaaacaata aaaagagttg tgaatgaggt ttttggaaat
    26461 tggggtgatt ttagtaaaaa aattgaaaaa catctaagcg aaaatataaa tataaattta
    26521 gataaattgg atatacaaaa atataatgtg ctcgtagcaa ctacagtaaa agaaaagatt
    26581 gatatgacaa tgaaggtaga agctattgaa cacttaaaaa gaaatttaga taacatgctt
    26641 gtaggtgctg aaaaagaata taaaatgagc gaattgttgg aaatattaaa aatggataaa
    26701 tatgatattg atgaatatga aggctatgaa gattgcataa catttattct tgatgaaaat
    26761 aaatatggtt cgggatggat tgaaattgat aaagaaccaa ataaaagtaa atacagatgc
    26821 gaacactcta tattgttgag aaaagatgga actattgcat catatagata cgagaataga
    26881 gaaatatcat ctaaagatat aatgagtgga tttgataatt ttggagattt gctatttaaa
    26941 atatttgctc atgggtcaaa aataattttg gatttaggaa atgatataga agattatgat
    27001 ttaacaaatg gagaagatta ttaaaatagg ggatggaaca aatgtcaaag tatgtattga
    27061 gatggcaaaa aggattatta ctagatgaac gcaagataaa ttattcatgt ggaagtaaag
    27121 aaatgttaaa aaagaaagct gaattattag ctaaagatga caagatactg cttgtaacaa
    27181 tagataaagt tgaagaagtt ataaaagata ctagaagcca aaaaatggct gaatattttg
    27241 aggatgaagg ggtggaagta tgataataca caaatttata atacatgttt tagataagaa
    27301 cagcgataca ccaatactaa atgattttga aggtagagtt agtcaagata ttgaagcttt
    27361 ctttcaaaag aaaataagca aagtatcaag agataatgat atcagaacag cagtatttaa
    27421 tgactatagt aacaatctaa ttaagaagtg ttgtgaacaa attatttatg atgaaagttc
    27481 atttttaaat aactctaaag agattgcagc ttatttattt gatgttatga agcttaatgc
    27541 tacattagaa tcttgcgact tatcaatttg cttatactct caaaaagatg aaaagaaagt
    27601 tgctatatta aagcttgatt acaataattc gtatactcat tcaattgagt ttaaagatga
    27661 taaatttaat atacagatgt ctaaaaatga aattaatata caagagacta aagcaattaa
    27721 aattggtgca ttgattggat taagtggaat taatgacgaa tatcatctaa aagtattgga
    27781 taaagatgca gagaaggaag aagctaattc taagtttgtt acagagtttc taaatgctac
    27841 taaagtgaaa gatgataagt ataagactaa gatgtttaaa gcttttgtgg actcttatat
    27901 agcacattta tatagtgata tgaagcaggg cgaagatgta agaggaatgt tactttatat
    27961 gttaagagaa aaacaaaaac ttgatataaa tgagtttgct gataaggcga taaaggatga
    28021 tttaaaagat agttttaagg accatataga agaaaaagga attgaaagtt ttaatattga
    28081 taaaaagtgg gttgaaaaga atctgaaaaa cagatgtatc aagacagata caggatttga
    28141 gataaaaggt aagatggagt actttgagga ttttatgaaa tatggtatta gacataatgg
    28201 gaatggaact gtagatatag ttattaagaa tgttaatttc tataatgaga agtaggtgct
    28261 catatgaaat atgtagctag ttttagtgga ggaaaagatt cagcagcaat gcttctttta
    28321 atattagaaa aaggtcttaa attagacgaa atagttttta tagatacagg attagaattt
    28381 aaagaaattt atgatataat agatgatttt gaaaaaagaa taaactttaa aataacaaga
    28441 attaaagcag aaaaaacctt cgaggaatac ttttatactg ttaatcaaca aggtaagcgt
    28501 aaagggcaaa tatggggttt tccgtatact ctaggggcat ggtgtaatag cagattaaaa
    28561 cttgctcctg ctaataaata ttttaataaa ctaggagagc ataaaaggta tattggaatt
    28621 gcctttgatg aacctagcag atataaaaga ctagaaaaaa actgcatagc accgttgttt
    28681 gaagaaaaaa tgactgaaaa agattgcttg aaatacttga aagaaaaagg tttctattat
    28741 gaaatacatc acagattcaa gcgaactggt tgttacttat gccctaaaca aagcctagag
    28801 agtctcagaa cattgagaag atactatcct gatttgtggg gggatatgct taaattggat
    28861 aaagatagtc ctgtaccttt tagagctaat ggggtcacag taaatgacct agaaaagcga
    28921 tttagtaatg aagatataga aaatgaaaga caaataagtt tctttcaaac agagaaggtg
    28981 agcatatgac taataaagaa atgtgcaagt caaagaatct tgatgaaaga gaagtgtgta
    29041 agaaatttag aaaagagatt tgtgctagtt gtataaatga taaaggagat tgcgagagta
    29101 aagattgtga tacagcatat aaaaattggt tggaggatat ttactatgta tagtacttat
    29161 aaagtaaaat taaagactaa aaaaacatta gaacaattaa gaaagcaagg agatataaat
    29221 tttgggagtt cagaagaagg attaaaaaga gcattaaaat ataataattt aattgatggt
    29281 ttagaagtaa ctgtaattaa gtttaaagat gtatattgtt tagctaactg tgatgaaaaa
    29341 gacgtagaaa aaataagaga tgcatattat cttttagagc aagataaata ttttggatgt
    29401 tatataaatg aatatgaacg atttaaaaaa gactggaaaa atggtagttg tgatggggaa
    29461 gctagtatgg tattttcaga tgatgaaatt gagataattg agaagctaag ggagggttaa
    29521 atatgaataa aagaattaaa atgaaaaaaa gattaattca taaaaagtgt gatgaaagat
    29581 gtgtcaacta tgactttgta attagcaata accttataac ttgtaatgtg tgtataggat
    29641 gcaaatacaa agaaaatatg gataaagtat gtgaagagaa ctataagaaa ttaagaagta
    29701 aatagaataa aatagtcaag gtaagtttgt gaatgaaact aaaagtctat agacttactt
    29761 tgacttataa aagggagttt ttaaaaaata ggaggtaata aaatgaataa atgtgaaggt
    29821 tgcaaatata gagcttatga ggaagatgga gaagtttatt tttactcaga tggaagttat
    29881 gaaggaggta tatgtgtagg agatacagtc atattgcagt catttaagga taaaaagttt
    29941 acagggattg agataaacaa agagattgag tattttgtta agcttggaaa tgggtatgtt
    30001 gagttgggaa taaaataaaa atttaaggag agataatgaa agttaatttt gtaatagatg
    30061 gagaaccaaa agcaaaagca cgtcctagaa tgagtacatc aactggcaag gcttatacac
    30121 ctgaccaaac catactctat gaaaattgga ttagacttat gtacaattct acagtaaagc
    30181 atttctttga gggtaatgtg aaaatgacag ttatttgtta ctttgacatt actaaaaaag
    30241 atagggaagc actgcagaaa aataaggtaa atactaaagc gtataaggat gctataggga
    30301 aggtagaagg gttaataaga ccaaacaaga aacccgattt agacaatata atcaagtctg
    30361 tagctgacag tttgaatggt atagcttata aagatgattc tcaaattgta gaagtggtga
    30421 gtaagaaata ttatagtgat aagccaagag ttgaagttgt actagaggat attatataaa
    30481 aagaatctaa ataaaagtca caagaaaatt attaatatac tctataaaaa acgatattaa
    30541 taaaattaaa caaatccata taaagatatg ttttttaaat ggatatgtct tattgagttt
    30601 ttgtgcagca gatgccagta aaaaataaat acaaagtctt attaagaaaa ctattaaatc
    30661 tcccataaaa tcctcctaag attagatgat ataaggttag gatactatga gatattaata
    30721 ataacaatag attttgcaga actgtaaata aattgaaatg aattattcaa aagagaaaag
    30781 gagagataga ttatgaatga aaatataaat aaagaaataa cagtacttgg aactttagaa
    30841 gttgagggaa tgaaatttca tgatattgag ggtgggtttg gaaaaggcaa gaaagcaatg
    30901 ttagtaaagg atatagctga gatacataat agagaactta aacatgtaaa tgagctaatt
    30961 aatagtaata taaagagatt taaaacaaat gtagatatta tagatttgaa agtgagtcgt
    31021 tctgagcgac taggtgattt aaaggctaat ccttcaaaag gattaggtta tgaagacgtt
    31081 ggatatagca aacaatcttt taatcaatca agaaatattt acttgttgtc tgagagaggt
    31141 tattcaaaac tacttaaaat actggaagac gataaggctt gggagcaata cgagaaaata
    31201 gttgatggat atttctctat gagaaaagaa ctaaataatc ctcttttaag tgcatcaaag
    31261 gagttacagg ctatatttat gctagataag aaacaagaag tcttagaaac taaaatagag
    31321 aatgttaatg agaaattaga gaactttatg gatgatgctc cactttttaa cattgaatgt
    31381 gagtgtattg ttaaagaggt taagagggta gcaacaaaat cacttggtgg gcatgtaagt
    31441 aaggcttata aaaataaatc tttaagaggt aaagtataca gtgatatata ccatcagatt
    31501 aaacgagagt ttggagtaga tagttataag gccataaagc gttgtcagtt agataaagta
    31561 ttagagattg taaacaatta taagttacct atagtgtttg aagaagaaat aagacttttg
    31621 aatagtcaat tatcaatagt tagttaaaag aaaaaaggag tgctttcaca ctccacttgt
    31681 caaaaatata aagcttttat ccaagattat tataacataa acaggagtgt ggaagtatgg
    31741 ataataatat caataaaaaa gaactattta aaaaagtaga aggtagacta catcattata
    31801 aatttttaag tgcagaaatt aaaaatcttg aattagatat agaaagtaga gaaaatgaga
    31861 tatttgggtg taaggctgtt ggatatgatg aaaaagtaag tccaacatat gcttttaatt
    31921 caagtgtgga gaatgagatt ataaaaaaag aaagagatat tactagattg aaaaaactga
    31981 aaaaagataa ggaaatagaa aagaagaaaa tagaaaatgc acttacatgc ttagatataa
    32041 gagaagaaca tttttttaaa ctgttttata atagcagaat gaaaaatagt atggtttata
    32101 tatccttaga aatgaactca gatagaaaaa catgtagatg tgtgagggaa aggttagtgt
    32161 ataaaattat ggatatgctt tatccaagaa ttaaggaaaa tgaactacca ttatttaaaa
    32221 attagaaaat tccccagttt ttccccagaa attctcactt tattccctac tttctcccct
    32281 ttttgattaa aaaagcatga gataatagta ttgtggaaat aaagatttcc ctctcaaaac
    32341 taaataattg ctaggttagt ttaaagggct aatctagcaa tatgaacaga ctaggcaggg
    32401 cgtgaggacg ctgttagttc aattctaact atgttcaaaa cctattaata cactatatgt
    32461 agtagttgaa ttaagactaa aatctcatac aattttgtat cttaattcag aagtctaaaa
    32521 accgagtggg gcttggtaac ctcactcacc atgcaagtag tggtttaatc taggttcgat
    32581 tcctagaact tgctaatatg tatctcccta ttaaaaagac taagtgcgag taaacttagt
    32641 ctttttaatt tttaaaacag aaaaaaatag atttattggt tagtatgtag aataacagag
    32701 aatatataga aaatttggtt agtaaaagat gattataaag gatatcctct aaaaacatag
    32761 aattttataa aaaaggatga aagtataagg aggatacaga tgatacaaga atctatacga
    32821 aaaaactata tagagtatat ggataattat ggttttagtg aggctgcaaa atataaaaat
    32881 aaagaattaa agaataaaaa aatctataaa tttataccat ttacagatga gttagaatgt
    32941 gaaaataaca actgtaaaaa gtgcccatat ataaataaaa accaaagaac tataaattct
    33001 ttaataaata aaaaaatatg gttgtcaaaa agtaataatt taaatgaccc ttttgaattg
    33061 aaaataatat atgcagataa agagagtgct agtaaaaaaa catacgatag caatgtttta
    33121 aattacatgc ttgatgtaat tataagtaat gtttatctaa cttgttttac aagtgatttt
    33181 aaaaataata tgcctatgtg ggctcattat gctaataatt ataatggact ttgtcttgaa
    33241 tttaagatag taaatcctaa aaatatatat ccagtaatat atgaagaaaa tgatagaata
    33301 aaatttaata atacattaag tgattattta actttgtgta tcaaggattt taagggtgaa
    33361 cttgatgaga taggacaaaa atatcaacaa gaactagcta aagtcataag tactactttt
    33421 gcatataaag attatgtttg gaattatgaa agagaatata ggttacttta ttcggatggt
    33481 gaaccaagag aggatgttaa gggaatatta ttgaatatga aagaaacagg aatagaatta
    33541 acaggaatat atataggtaa tcgaatagat gaaaaatata aaactgatat taagaatatt
    33601 gcaaaagaaa atactctaga tttatatgaa gtgtatatgg atgaaaatag taataaggtt
    33661 tcactggcat ataggccagt agaaatataa acaatatatt ttattgctta ctttaaggct
    33721 ataactagaa atttttagtt aaaattttat tattttgtag ttgtcgaata gtttttgaag
    33781 gatattgacc tttgaagttg aattttatac tttggagggg ataatgcaga ataaattaat
    33841 gagagtgaat aatagatagg tgtatttagg agggataaaa attgagcatt aaagttaaag
    33901 tatgggctaa attaccatat attataaaac tagaagaaga gaaagattat gaatttagtt
    33961 ttctatttga tgattttgat ttatttaagc ttaatatgag gtttaatgat gaaaatgatt
    34021 ttttaattta taataatgaa tatcctggta atgtgtgtca gcatatagaa ttagaagtaa
    34081 tttataaata tgttgattat acaaaatata aaactacaaa atgtattaat agtaatgaca
    34141 attattttga agtagaggtg ccattagata aaactacaga gatttttgga tgcatgaata
    34201 aaagacttaa tgaaatatta aattttttaa gagagaagtc taatatgttt tggattgatg
    34261 aatttaatct tacacatata aattatcatt ctgagaatga ggtacgtttt aacttttatt
    34321 ctccgaatgt aaatccaagt tctgttgtaa ctagttttat agaacataca gattactata
    34381 tgatttctaa aaacttcaaa acaaataatg ttggtgaaga tacctttaaa aactttgatt
    34441 ctaataagat aaaaatgaag gtttttaatg aatatataga caaagcagag aaagcactgt
    34501 atgaatataa ttatgaaaat tttataatat attgtagtat atcagttgaa tcatttatta
    34561 ttcaatatat agatgaaata gctaatcaag acgatattat ttataaacaa cttgaaaaaa
    34621 caaactctaa ttatataaat ttgtattata atgtgttatt aaaatatcta acaggcaaaa
    34681 gccttataga agttgataaa aaagcatgta cacatttaac aagactttat agattaagaa
    34741 attcattaat gcataaggga attatagata gtaaatcatt agaaaaagca ggtataatga
    34801 aacttgattt taatgagtgt aataaaattt tagattcagc aaagacaagt tttaaattag
    34861 taaagagtat aacagttaaa cctaagaatg atattaatta ataaaaataa taattactgg
    34921 aaaagaactc aataaatagg gttctttttt tattcccaaa acgacaaaaa cgaggtggtg
    34981 gtgtggcaaa atatgaatac tggataacag aagaaggatt aattaagatt gaaggatggg
    35041 caagagatgg gcttacagat gaacaaatag catttaatat tggaataaat gtcaaaacac
    35101 tatatgactg gaaaaagaag tatagtaata tttgtaatgc cttaaaaaag ggaaaagaag
    35161 taattgacag gcaggttgaa aatgccctat taaaaagagc attaggttat gaatatgatg
    35221 agataacata tgaagaaggt caagaaacta aaagagtaac taaacaagta gtaccagata
    35281 ctacagcaca gatattctgg ttgaaaaata gaaaaccagc ggaatggagg gataaaagag
    35341 atattgaaca tagtggtaat ctaggagata ttacaataaa ggtaggcgat gaggaatatg
    35401 gcaattaatt tagaaattaa tccagatgta tttaatccaa tatatttgaa gcatcaactt
    35461 aataataaca ataggtatca gatttacttt ggtggttcat cctcgggtaa atctttttct
    35521 ttagctcaaa gaacagtatt agatgtattt aaggggaata ggaattattt aattgttaga
    35581 aatgttcaaa gcactctaaa gaggtcctgt ttaaatgaga taacaaaggc tattaataat
    35641 tttaagttaa atgagtattt tcaagtaaat aaaaccgata tgataataac ttgtaagcta
    35701 aataataaac agatattatt ttgtggctta gatgatgttg agaaagttaa atcaataact
    35761 ccaatagatg gtgtaataac tgatatatgg gtagaagaag caacagagac agattataaa
    35821 gccgtcaaac aacttgataa gagacttaga ggaaagtcta aagtagtaaa aagactaaca
    35881 ttaagcttca atccaatact taaagaccat tggctatata cagagtattt tgatatatgg
    35941 gaagatgata aacagtatgt agaaaaagat aatgtaagta ttctaaaaac tacatataaa
    36001 gataataaat tcttggcaga agatgatata aaagctttag aaaatgaaag tgataaatat
    36061 tattatgaag tttacactct tggaaattgg ggtgtacttg gtgctgtcat atttaagaat
    36121 tggagagttg aggatttctc agatattgaa agtacatttg ataactttag gcatggaatt
    36181 gattggggat ttgctgatga cccatttgca tatgtaaaat cacactatga taggatgaga
    36241 agaaaattat atatatgtga tgaaatagaa gcagttggat tattaaatag agaagctgca
    36301 cctttggtta gtaaaaaagc gaatggagat ttagttatct gtgataatgc aagtccaaaa
    36361 gatgtagctg aatttagtga cttaagaatc aatgcagttt cagcaagaaa aggagctggt
    36421 tctattgaat atggtattaa atttttacaa gggcttgaaa ttataataca tccaagatgc
    36481 caaaacttca aaaatgagat aaataaatat aaatataaag aggataagaa tggaaatatc
    36541 ttacctattg cagtagataa agataaccat ttaatagatg cactgagata tagcttagaa
    36601 aatgatatgg agtatggagg aataagcttc ttaaagtaag gaggtgttaa atatttatat
    36661 aagtgaaaca gatttaataa aagctcagct aaaaaaagag agtactttta atctggcgaa
    36721 agttatagag cattatattt taaagcatag accagaaaag tatcaagaag gagaagcata
    36781 ctattatggt aatgctaata taaaaaataa aagaagatat tatattttag atggtgctaa
    36841 ggttgatgat tttactaaag ttaataataa agcagttaat aattatcata agcttttagt
    36901 tgaccaaaag gtaggctaca gtgttggaaa accaatagta tttaatgcag atgataataa
    36961 ttttactaag cttttaaatg aattattagg agaagaattt gatgatacaa taacagaact
    37021 ctatctcaat gcaagcaata agggaataga atggttacat ccatatatta atagaaaagg
    37081 agagtttaaa tatgtaataa taccagcaga agaagctatt cctatttggg ataacaagag
    37141 gcaaaatgaa ttagttgcct ttattagatt ttactttatt gaggatatag atggaaataa
    37201 gataaaaaga gttgaatact atacagaaaa tgaagtaatt tactttattg aaaaaggaaa
    37261 tagttttgtt caagaacttt tatatgatga atatggaaaa ttaacagaga tacaagaggg
    37321 tcattttaga gtaaataaca aagagcaagg atggggtaaa gttccattta taccatttaa
    37381 aaacaatgag aaaagcgtat ctgatttaac tttttacaag tctttaattg atatatatga
    37441 taataacatt tctactcttg cagataacct agatgaagta caagaagcta tgtacatact
    37501 aaaagagtat ggaggtactg atttagtaga atttgcaaat aacataagat attataaagc
    37561 cattaaagta ggagctaatg gaggggtaga taagctggag ataaatatac cagttgaagc
    37621 taaaaaggag cttcttaata gattggaaaa gaatataatt atctttggtc aaggagttaa
    37681 tccagaatct caaaacacag gtgacaaatc gggtgtagca cttaaatttt tatattcact
    37741 acttgactta aaatgttcta agactgaaaa gaagtttaaa aaagcaatta gagagctttt
    37801 atggtttgtg tgtgagtatt taaagataag tggtagtaag agctatgatt ataaaacagt
    37861 tcaaattact tttaatcact ctatgataat aaatgaagct gaaaagatag atatggcagc
    37921 taaatcaact ggaattgtat cagatgaaac tattgtttcc aatcatcctt gggttgagga
    37981 tgttaatgac gaacttgaga gacttaaaaa acaggaagat actcaaaaag agtatgatga
    38041 tttaattcct aataatcaag atggtgttat agatgaaata taaagattat tggagaaaga
    38101 gatttgaaca attagaagaa gttcaaaata acaaaagtgt aaaatattat cttgaattag
    38161 aaaagcaata taaactagct atgaatagta tagaaaaaga tatattagca tggtacaaca
    38221 gatttgccaa aaatgaagga atatctttat tagaagctaa gaaactacta aatacaagag
    38281 aactagaaga gtttaaatgg agtgtcgaag aatatattag acatggtaaa gaaaatgcta
    38341 taaatcaaaa gtggatgaaa gagttagaaa atgctagtgc aagagttcat ataacaagac
    38401 ttgaagcttt aaagttacaa atacagcaac aagtagaagt tttatatgga aatgaacttg
    38461 atggtattga taaactaatg agagatattt atacaagtgg atactatcat acagctttta
    38521 atgttcaaca aggagtaaac gttggttgga gtttaatgag tcttgatact aatagaataa
    38581 ataaagttat ctctaaacca tggactagtg atggattaaa ttttagtgaa aggatttggg
    38641 gcaaacatag acctgcttta attaatgagt tacacactaa attgacacaa tcaattatta
    38701 gaggtgagaa tccaaaaaat ctagtcaatg actttgctaa gagctttaat gtatctaaat
    38761 cacaagctaa gaatttaata atgactgaat cagctttctt tgcatcagca agtagaaaag
    38821 attgttttaa tgatttagat gtagagaaat atgagattat tgctacatta gatttaagaa
    38881 cttcaaatat atgcagagag ttagatggaa aagtatttga tatgaaagat tatcaagttg
    38941 gaataacagc tccaccattt cattgtcgtt gtaggacaac aacagctcct tggtttgagg
    39001 atgaagaagg ttacagagca gcaaaaggag aagatggaaa aacatattat gtaccatcta
    39061 gtatgaagta taatgagtgg tatgagaagt atgttaaaca taatagtatc ttagaaataa
    39121 aaaatagtgc tataatagat agcataaaag aagatattaa aaatggtaaa tataatttaa
    39181 atattcatga tgggaaacaa ggaaaacatt taaaagagca taataattat atagaaggaa
    39241 gaagctattt aactataaca aaagaagaag ctcaagaact tgtgaataag catgctggca
    39301 atggaatcat aaaatttaat cgaagtggag aatgggataa aaaagaactt atagaagttg
    39361 ataagaatat aggggtcaat gttaataata ttacgggtga aaaaactctt acaaataagt
    39421 ttaagataca ttattccaaa actggaacac atatagtacc agctttataa ggaggaaaaa
    39481 taaaatgaaa ttatgggaat atgtagggaa aaatgttcaa ataacttgtg tagataagca
    39541 aataataaga ggaaagtgtg atggatatac acaagcttta gataatgaac cagaaatagc
    39601 aagtatatca atagctaggg atggttatgg aattgaagtt tatgaaaatg aaatagaatc
    39661 tatcgaaaat ataaataagg aatgactaag catgtactta aaaataagta gatgctttta
    39721 ttttgtaaaa aatgaaagga gaaatttaaa atggattggt taaaagaatt gctagaagga
    39781 ataaaagtag aggataacaa aattgatgta gcttctcttc aaaaatctat agaaaagaaa
    39841 ataaaagaga ctacaattac tcaagaagat tatacaaatc ttgaaacaca gcttaataca
    39901 gctaatgaaa ctattaaaaa gtttgaagga ggtatgacaa aagaagatgt agagaatcta
    39961 aaaacaactt atgaaactga taagaaaact ttggaagaaa cctacaaaaa agaaattgaa
    40021 gaaaaagatt ttaattactg gttaggtgat gcttttaaat ctgttaaatg tagagatgaa
    40081 atagcattaa aagctcattt agatatagaa gcactaagaa atagtaaaga cagacaaaaa
    40141 gcttttgaag agcaaataaa tcctttgaaa caggataaag attatttgtt taatgcaaca
    40201 ctagaaggtg aagaacctaa aatagatact ataacaccag ggcaagagcc taagataaat
    40261 gattttggtt ttaattttac tggggtaaga cctcatgaaa ataataataa ataggaggaa
    40321 ataaaatggc agcactaaat tatgcaaaag aatattcaaa tgttttagca caagcatatc
    40381 cttatacttt aaacttcggg gatttgtatg caacaccaaa taatggaaga tatagatgga
    40441 ctggttctaa aacaatagaa ataccaacta tatctacaac tggaagagta gattcaaaca
    40501 gagatacaat agcagtagct caaagaaact atgataatgc ttgggaacct aaggtattaa
    40561 ctaatcaaag gaaatggtca acattggttc atccagcaga tataaaccaa actaattatg
    40621 tggcttcaat aggcaatata acaaaagtat ataatgagga acaaaagttt ccagagatgg
    40681 atgcttattg tatatctaaa atatatgctg attggaccgc attaggtaac acagcagata
    40741 caactgttct tacaacagca aacgtattag aagtatttga taagttaatg gaaaaaatga
    40801 cagaagctag agtacctgaa aatggaagaa tattgtatgt tactccagta gtaaatacac
    40861 ttatcaaaaa tgcaaaagag atacaaagaa cagtaaacat aaaagatggt ggaacttctt
    40921 taaatagaca aaccacagat attgacacag ttaaaataat taaagtacca tctaatctaa
    40981 tgaaaactgc atatgatttt acaactggat ggaaagtagg agtaggagct aaacaaatct
    41041 ttatgtcctt agttcaccca agtgcaataa ttacacctgt ttcttatcag ttctctaagt
    41101 tagacgaacc aacagcagtt acagagggaa aatacttcta ctttgaagaa agttttgagg
    41161 atgtatttat attaaataaa aaagctgatg caatacaatt tgttgttgaa ggagctggag
    41221 tataatggca caagtaagga aattaaatag aatattaact atagaagagt gtaaaataga
    41281 tgatttctta gagatgggat atgatttgat agatgaaact ggtaaggcag taaagtatgg
    41341 caagtcatta aatgtaaaag atttaatagc tgaaaataat attttaaggt caaaagttga
    41401 gtctttagaa gaagaaaata agcagcttaa agagaaaaat aagcttacta aaaagtaggt
    41461 gaaaattatg gaaaataatc tgattgatga aatagaaaaa agacttgaaa gttttggata
    41521 tatattaaaa gatggagata agtggttaat agattttata agagaaaaaa tagaaaatat
    41581 tattaaacta gattgtaata taaaaactat gccaattgaa ttgaaagaaa ttgaagttga
    41641 tatgatagtt ggagagttct tatttaccaa gaaaaatatg ggtcaattag atatagaaag
    41701 cattaacttt gaagctgtag aaaagtctat atcagaaggt gatacaaagg tagattttgc
    41761 tataggaagt ggttctcaaa caccagaaca acgctttgat agcttaatag cttatcttac
    41821 tacttatggt aagaataata tattaacctt taggtgctta agatggtaag taaaactaga
    41881 aaagcaatag aaatgttata tagagataaa tgtactatag ttgagtatca gccaattaaa
    41941 gaccctgtaa caaaacgaac taacaataaa gaagtgattg tattagaaaa tcaaccatgt
    42001 aaactttcat ataaaaatat agtttctgct acagaaggga aagtagctaa gctagagcaa
    42061 actattaaac tctttatatc tccagatata gaaattaaag caggttcaaa acttattata
    42121 aatgataaag agtatgtaag aagtggagaa tcagctatat atccaaatca tcaagaaata
    42181 atacttgagt tatttaagga taaagcataa tggctagatg gggcagtgtt gattttagag
    42241 aatttaaaag agtttgtaaa aagatggagg agcttacaaa gattgattta gataagtttt
    42301 gcaaggatgc agcaagagaa ttagcagcac gattacttgg gaaagtaatt agaagaacac
    42361 cagttgatac aggattctta cgacaaggat ggaatggagt ggcttatgct aggtcgcttc
    42421 ctgtgtataa acaaggaaat aattatatta tagaggttgt taatccgact gaatatgcct
    42481 taacacaatg gggcatataa aacccagcaa aatcggtaaa cgctaagtgt aatagtgtta
    42541 cattataaag taggtagaat atggacatag aataactctt gatttataat gtataaaaga
    42601 ggtgatttta tggcaaaatt tttagatatt acaggaaaaa aatttggaag gctaagagtc
    42661 attaaatttt ctaaagagat aaaaagtggt aaaagaaata gaaaatattg gttatgtaag
    42721 tgtgattgtg gaaatttcaa agaaataaga actgactctt taactagtgg cttagtacaa
    42781 tcttgtggat gtttaaaaaa agaacaagat aaattaaatt taacagacaa ataccaattt
    42841 aaaaagaaat ataaggttca aaataaaaga ctttacagta tatggaaggg tataatatct
    42901 agatgtacag ataaaaataa taaaagatac aatagatatg gtgaaaggaa tataattgtg
    42961 tgtgatgaat ggttttgcta tgataatttt gcaaattggg cattgagtaa tggatattca
    43021 gagaaactta caattgatag aataaataat gaaggaaatt atgaatcaag caattgtaga
    43081 tgggtggata taaagacaca atgtagaaat aggtcaacaa atatattagt aaagcatgaa
    43141 gaaaaagaaa ttacattgat agagctttct gaaaaaacag gtatttcata ttcttgctta
    43201 agaagtagat attctaaggg attagtagga aataatctta tagaaaaagt taagattatt
    43261 gaagaaagca gagctaagtt atctattgag gatgtaaaag aaattagaaa aaagtattct
    43321 gatggatata caataaaaca actaagtgaa atatatcctg taacatattc atctatatca
    43381 aatatagtcc atagaagaac atggaaaaat atttaattaa ttatatatgc caataccgag
    43441 gaaaacctat agattgcgaa taggctatag gtttccgtag agcgtagaga gtgaataaat
    43501 ataatctctc caagagtgct gggcaactaa ataaagttta ttttgttgat gatgtacgcc
    43561 gaacttatag gaaactataa gagctagagg ataaaaagcc tttaggataa caaaatgcat
    43621 atgttgagtt tgggcataga actaaaagtg gtaagggatg ggttaaagga caacatttct
    43681 taacaatttc agagatggaa ctacaaagcc aaattgataa gattatagag aaaaagttat
    43741 taatattact taaaggagta tttgatgctt aataatataa ttgatggaat atctattaaa
    43801 ttagataaaa catttggaga gagttataca atttatagtg aagatgtgga gcaaggtata
    43861 aatgaacctt gtttttttat ttgccctcta aatccaagta agacatctta tccaaatggt
    43921 agaacactaa aaaagaactc ttttgatgta cattattttc ctcgttcaaa agataagagt
    43981 tttgaaataa atgaggtagc tgagatgcta cttgaggaat tagagtatat agaaattgat
    44041 ggagatttag ttagaggcac aaatatgaat tttgaaatta tagataatgt tcttcatttc
    44101 ttcgttgatt ataactactt cactataaaa agtaatgata cagaaaaaat gaatgatgtt
    44161 gaattatttg gtggtttgaa gagaggtgat aattttgaat aaaacattaa gcaaagaaga
    44221 tgactacaag tttactaagg agcaaatagt taattctaag aagtatgtaa atagaaaaga
    44281 cttattaaat gcaattttaa aagaaaatga gttatattcc ttctcagaag tagaggaaat
    44341 aataaataat tttatgaaag gagtgagtta gatggcttta ggtggaggaa catttgtaac
    44401 acaaaataag gtcctacctg gtgcatatat aaattttgta agtgctacaa gggcaaccag
    44461 ttcattatcg gatagaggta ttgttgcaat gcctttagag ttagattggg gcatagatga
    44521 agaaattttc acagtaacca gtgatgattt tgagaagtat tcaactaagt attttggata
    44581 tgattatact catgagaagc tgaaaggttt gagagattta ttcaaaaata taaggttggg
    44641 atatttttat aaattgaata aaggtgttaa agctagttgc agtattgcta cagctaagta
    44701 ctcaggtact agaggtaatg atttaaaagt tatagttaca acaaacattg atgataacac
    44761 taagtttgat gttgtaacac ttttggataa taagaaagta gatacccaaa tagcaaaagt
    44821 tattacagac ttacaggaca atgactatat tacttggaag aaggatacaa cactagaagc
    44881 aagtgcaggg cttgtattta ctggtggaac taatggcgaa tcagtcacag gagcagagta
    44941 tcaagctttc ttggataaaa tagaaagcta ctcatttaat gcactaggca gtttggctac
    45001 aacagcagaa attaaaagtt tatttgtaga gtttactaaa agaatgagag ataaagtagg
    45061 agctaagttt caaactgtac tatataaaaa gaatgatgca gattacgaag gtgtagtatc
    45121 tgtagaaaat aaagttaaag atactgggtt attagaatct agtttagttt attggactac
    45181 tggagctata gcaggatgcg atataaataa atctaatact aataaaaagt atgatggtga
    45241 gtttgatgtt gatgttaatt atacacaaat acaacttgaa gaagctttaa aaactggtaa
    45301 atttatattc cacaaggtgg gagatgaagt tcatgtgtta gaggatataa atacttttgt
    45361 atcatttaca gacgataaaa atgacgattt ttcaagtaac caaagtgtta gagtacttga
    45421 ccaaattgct aatgatattg caactttatt taatgaaaag tatttaggta aagttccgaa
    45481 tgataaggca ggaagaataa gtttctggaa tgatgttgtt aaacaccata aagaattaga
    45541 gaatataagg gcaatagaag attttaaaac tgatgatgtt agtgtagagc ttggaaatga
    45601 taagaaaact gtcatagtat ctgatgctgt taaggttata aatgctatga gtaagcttta
    45661 tatgactgtt tcagttagtt aagagaggag tgtgatatat gtttcagcaa ataaaagcaa
    45721 gagatacaat aagtgcatct aaggcagaat gctatgttac tatcgagggt aaaagatata
    45781 attttatgca agctattaac ttagaagcta agatggaaaa aaataaaagt gaagttccta
    45841 tcttaggtag cactacaaaa gggaataaaa gtactggaag caaatacaca ggaagtgcaa
    45901 catttcacta caatacttct atatttagag agcttcttta taggtacaaa gagactggtg
    45961 aagatattta ttttgatata caggtaacaa atgaagaccc aacgagttca gctggacgtc
    46021 aaactataat acttaaggat tgcaacatgg acagtggaat tatagttaaa tttgatgcag
    46081 atggtgagta tcttgatgaa gatatggact ttacatgcga ggattgggaa ttggttgaaa
    46141 agttcaatat aataaatgga atggaataaa acacacattt ataaattata gatgtgtatt
    46201 ttatatttat ataaataagg agatggttaa aattaaagat aaatacaaaa tgaaagactc
    46261 agtttcattt gactatagta ataaaagaaa gatagaagaa tgtgtagggg agatgtatag
    46321 aaaagcagga ttatttttag tagatattgc tgataaactg gcacttgaca caattgaagg
    46381 ttcatcatta aaaccaatta caataacaat caaattagat gaaaatggta ttacaacaat
    46441 agaaaaacaa acaaaatatt tagttatgga ggtagaataa tatgggagat ttaaacgctt
    46501 ttttaagtca aaatgcaata aaagtagaga atagaaagta tgtagcaagt aatagattta
    46561 taaatgaaga agggaaagcg atagaatggg aaataagagc attatcttca gaagaagatg
    46621 ctgcaataag aaaaaactgt ccaaagagag agccaatttt aaataaaaaa ggtaaacata
    46681 caggacaata caatactgta actgactaca ataaatatta cgaagaacta agtatagctt
    46741 gcacagtttt tcctgatttg aatgactcaa tgttacagga tagttataga gtcatggggg
    46801 ctaatcagct acttaaagca atgttaactc ctggtgaata tgcagaatat gtccaagagg
    46861 ttttggatat aaatggattt gataattcat ttgaggataa ggtagaagaa gcaaaaaact
    46921 aatttatgaa ggtgattatg attctaatat agctcattat tgccttcata agtttaaatg
    46981 gaaaccgcat gaatatatgg atttaccagt tgatgaaaaa gcatttgttg ctgcttctat
    47041 agatatcaaa gtagaagaag aaaaagaaga agctaaaaaa gctgacaaag atgcaaagag
    47101 aggtagaaga agataatctc tggtgtaaaa attttactaa tatagtataa tatatttaaa
    47161 aattgtactg ggggattaaa taaatgggat tgtttagtaa aaagaataag aaaccttgtt
    47221 gtatttgcgg aagcgaaaaa ggacttatgc catctataga aggtgaaaat ttttgtacag
    47281 cttgtaattg caagtacata gatttctctg aaaatatttt aaaagtaact agtattatga
    47341 aaatgatgtc aaactcagaa ggaatgaaaa agtttataga agttgaaaag aaaaatttaa
    47401 aattgttaga gaagttcacc gagacaaaaa gtataaattc ttcaatttct tttgatgaag
    47461 agcaaaatct tttaaaaata tcatataaaa atagaaatca aatattagta gagaaaataa
    47521 taaaatttga tgatatatta gaatttgaac ttttggaaga tggagaaact atagttaaag
    47581 gtggtttagg tcgtgctata actggaggag tcttattcgg aggtacaggg gctgtagttg
    47641 gaggaattac aggtaaaaaa acaagtagaa aagttgtaga aatatttaaa ataaaaataa
    47701 ctgtaaagga cataaataat ccaattgaat atataaattt aattaatagt aaagtaaaaa
    47761 caaactcttc tatttatcag aaagcttttt ctgatgctca agaaatatta tcaatactat
    47821 caataattac aaaatataat gtaatggaag acaaaaaaaa gtctatatct agttctacag
    47881 ctgatgaaat attaaaatat aagaatttgt tagatatgga agctattaca caagaagaat
    47941 ttgatgctaa gaaaaaagaa ttgctaaatt tataatatat aagcacttac ttaaaaataa
    48001 gtaagtgctt atattatgtt aaaaaagaaa ggaggttaaa aatggcaact atacaaacat
    48061 ctatccgaat tttcgacgga atgacacctg cttttagaca catgaataat gctatgaata
    48121 ttgtattaag ttcattcgag caattacaaa gaacatctag caatgctata gatgctaata
    48181 gtattagaac agctagagaa gaactagcac gtgcagaagc tggctttgat agactagaac
    48241 aacaaataag agaatcagat aatcaacagc gaaggcttaa tgaggatata aataagggtg
    48301 caagttctac agatagatta gttggaagtg caaagaagct agcagcaacc tacttaggta
    48361 taagaacgtt aggaggtcta ggaaatttaa gcgaccagat gacaagtact aacgcgagac
    48421 ttagtatgat aaatgatggt caactctcag atggaggatt aaataagatg attttccaat
    48481 ctgctgaaag gtctcgtgca tcttacttag atactgcaaa aatagtttca cgaataggca
    48541 tgaacgcagg taaggcgttt agcagtacaa aagaaattgt aggttttgca gagcaactaa
    48601 ataaaaagtt cgtaattgct ggagcaagta ctgaagaaat gaactcagca ttgttacaac
    48661 taacccaagg gttgggttct ggtgtattaa gaggtgagga actaaatgct gtatttgagt
    48721 cagcacctaa catcatccaa tcgattgcag attatttgga cgtagacata ggaaaaataa
    48781 gaggaatggc atcagaggga atgttaacgg cagatattgt aaaaaactca ttactttcag
    48841 cagcagagca gaccaatgca gagttcgaga agatgcctta tacgctaggt caaatcttta
    48901 ctagtgtaaa aaataatgca gttatggtat ttggagctat acagaagaaa attgaggaca
    48961 cagtttcaag caggggattt cgaactttca taactgatgt taaagactca ttatatgtac
    49021 ttggagcagt tgggtttaat gtatttagtg gatttattaa tttactgagt agtccagctt
    49081 ttcagaattt ttttaatgtg atgattgttg gaactagttt agttgtacaa gggctaggtt
    49141 ggataataac acaagcactt agtgttgcta atgtattttc gcgaaattgg agtataattt
    49201 cacctataat tttaggtgta gtttcagcta ttagtaccta tataatagct cttggtatta
    49261 tgcaagcagt tactatagct ggaactgtag caaattggat gtcgtggaca tctgaagtta
    49321 ttagacaaag aggaatttta ggaacagcta gagctttagc gataggcaaa gctgaacaat
    49381 ggggatttaa tgctgctata tatgcatgtc ccattttttg gatagtttta ggtataattg
    49441 cagtaatatc tgctgtattt atattagtag cagtttacaa tcactttgca ggcacaagta
    49501 tttctgcaat cagtcttata gttggagctt ggtattggtt atgtgcagtt gtttacaacg
    49561 taattgtagg gatagtaaat gctataaata tctgtgtggt tgaaatagca aatatcttta
    49621 gaactggatt atatgcagtg caatgtttct ttattgatat ggctaatgca ggactcaagg
    49681 caggtgttaa tttagacaaa gcttttgata aatttgctac caatctagca aatggtatta
    49741 taaaagctgt taatatagct gtaaaaggat tgaattggtt agtacaacag attaataaaa
    49801 ttccaggaat tgatttacca caaatgaaag aatttcaaaa agtaaatact gtaattggta
    49861 caaaaacaac atttaaaccc attcaaaaac cgcctgagcc taaagcatgg aaaccagaat
    49921 tagtagagta caaaaattta aagtcagaat ttataaaagg atatgacgta ggacatcaat
    49981 tacaaaacaa attgaaagat acttttgata tcagtaaaat agcagaagat gcaaagaaaa
    50041 aattaggatt agatgacctt tgggataaga agtatggatt aggaaatgga tttggttcag
    50101 ctggattaaa ttcacctttg ggcgacgcag caaaaggagc aaaggacaca gcaggaaaca
    50161 ctgcaaaaat ggcaaagact atggataaaa gtcaagaaga tttaaaatat cttagagata
    50221 ttgcagagca agaaacaata aaccgattta caggagtcaa cattaaaatt gatatgaaca
    50281 atacaaataa cataagcaaa gatgcagatg tggatggtat agtaaacgtc ttaacagaaa
    50341 aattaaatga tgccatggtt gtttcagccg aaggaatagt ttaggaagga gggatataaa
    50401 tggcttatga tttttaccta gatggagtac aactaccaat cgcaccaccc aagcttgaag
    50461 tcaaagtgac aaataaaaac aagacagttg atttaataaa tgttggagaa gtaaacatac
    50521 taaaaaaaga aggattatct gaaataagtt ttgaagcaga atttacacat aataagttgc
    50581 cattctatcg tggagctttt agggatgttc aattcttttt aagtaaactg gaactattaa
    50641 aaactgattg taagccattt caatttattg tatcgaggga attaggtaat aaagtactat
    50701 ttaacactaa tataaaagta tctcttgaag agtatgctat ttcagaagat gcagaaaatg
    50761 gctcagatac aaaagttgca ataaagttaa agcaatatag agattactca actaaaaagt
    50821 tagttcttgc ccctcctaaa aatgagactg gtagacctaa tgtaaagata gagccaaaac
    50881 gagttgattc agtcaatgcc acaaacacta aaacatatac agtaaaagca ggggatagcc
    50941 tttggtcaat ttgtcagaaa caacttggta atggttcatt atataagaaa gtatacgaat
    51001 taaataaatc tatgatggat aaggcaaata aggggaagaa tttaagtaaa tacaccattt
    51061 ataaagggca ggtgttaaaa cttggttgat gaattagtgt tagcaaatga tagagatgta
    51121 agattagtaa tagctcattg ggaagatttc tacgaacctg ctgtgattga tggtatcaca
    51181 tgggagatag aaagacgagg aacaccatct aaacttgaat ttacaatagt catggatgat
    51241 atattagagt tttgtgaagg taactctgta agactatatt acaaaggtgt aggtatattc
    51301 tatggatata tatttcagaa gaaaagagat aaagaaaatc acattaaaat tgttgcttac
    51361 gaccagttaa gatattttaa gaacaaagat acttatgtgt atagcaataa aacagcaagt
    51421 gaacttgtaa aaatgttggc taaagatttt aatttaaaat acaatgtcat agaagatact
    51481 aagtataaac tatctagagt cgaagaaaat aaaacactct ttgacatgat actaacagca
    51541 ctagatgata ctctaagaga gaaaaaagaa atgtatacct tgtatgatga ttttggaaga
    51601 ataacattaa agaatgttgc atcaatgaaa ctggatactg tcatgaacaa tgatgtcata
    51661 gaggactttg attataattc aagtatagat agtgatactt atacaaaaat caaacttgta
    51721 agagacaacg aggagtcagg aaaaagagat gtgtatattg ctcaagactc tacacatatg
    51781 aggagttggg gaatacttca aatgtttgag acagttgata aaaatatgaa tgaagcagag
    51841 ataaaacaaa agtgtgatat acttctaaaa ctatataata agaaaactaa gtcattaagt
    51901 ttaaaaaatg cacttggaga tattagagtg agagcaggtt gtttagtacc tgttttttta
    51961 aatctaggag atattaaact tcaaaattat atgctagttg agaaagtaaa acatacattt
    52021 gaaaataatt cacatttcat ggatttgact cttgttgatg gagatgaatt tgcttcttat
    52081 tcttcaagct catattcaag tggaaatact aacaataagg atgaaaagaa aaatggtcct
    52141 gcacaaagta ttacgaaaaa aaatacaggt aaaaaagttc ctgctatatt tactgcatat
    52201 tatccaggga acaatgcaat ggaaggcgga aaaacagatt gcaatggaaa gccacttgat
    52261 gtaaaatcaa gaactgttgc tggtccaatg aatcgagaag gagttaagaa aacttggtat
    52321 actgatgatt ttctaaagaa acatccagtt tttgaatatg gagataaagt aaaaattata
    52381 cttcctggta ctgcctatga caacaaagta tatacagtta aagataatgg aggaagaata
    52441 tatgttgaaa caaacggaac atatcatata gatatactat tagctaatgc tagtgaatgt
    52501 aaaaaatttg gtagaaagaa tggctatata attataggtg gagatgaaga acaaacatat
    52561 caagttgaag gtaataacca aagtagtaca aataataact ctaaagaaga taaattaatt
    52621 agtatagcaa aaagtaaact gggttgtaat tatgtgtatg gagcagaagg tcctaataat
    52681 tttgattgca gtgggtttac tcaatggtgt tataaacaaa taggtataaa aattcctcgt
    52741 actgcttctg cacaaagtaa agcaggaaaa gcagtagatt taaaagatag aagcaagtgg
    52801 aaagcaggag atttattgtg cagaattgga ggaggaagta acaaccatgt tgtgatgtat
    52861 attggaaaca atcaaataat tcattcacca caaacaggag atgtggtaaa aatagaatct
    52921 gttaattctt atagaaaagg aaaagcatat acacatgtga gaagatttat ataagtgagg
    52981 tgataaagtg tcacaagaat tattgcaaat aattaagaag actgcaatag atgcagtaga
    53041 aacaagcaac ccaatgcaga ttgcatttgg aactatagaa agtcttaatc cattagtagt
    53101 taagatagaa caaaaactat ctattggtga aatttttcta atacaaacag atacatttaa
    53161 aagatataca gataaaaaga taggagataa attagtctta attaggatgc aaggagggca
    53221 acaatacttg attttagata ggatgtgatg aaatgttacc aacagataac attgactatg
    53281 atatagaaga tgtatcgata attaattttg atgttagaca agaaccaagt aagacgttta
    53341 aattgaatat agagaaaaat agagtagatg gtatttgtga tgatgtagaa gcattaaaac
    53401 aaaccatttt tttaatttta aatactgaaa ggtatgagca ccttatttat tctagaaatt
    53461 atggtgttga attaaatgat ttaattggag aacctatttc atatgtaata cccgaacttg
    53521 aaagaaggat aacagaagca ctaattcaag atgataggat tgaaaatata gataattttg
    53581 agtttcaaaa tataaagggt aaagtacaat gtagattttc agttcataca aaatatggaa
    53641 atataaaagc agagaaggtg gtgagtgtat aattgtttga gttaatgaca tttgaaaata
    53701 taattaaaag aatgttagat agtgtaccag atacttttga taaaagggaa ggttctataa
    53761 tatataatgc tcttgctcct gttgctatag aacttacaga aacatacatt gctatggatg
    53821 aattactaga ccaaacattc gtagatactg ctagttatta ttatttagag aagagatgta
    53881 aagagagagg tattacacca cttgaagcca ctaatacaat tgcaaaagga gtttttaaca
    53941 tagatattcc tattgattct aggtttaatc taggagaata taactatgta gcaattgaga
    54001 gaatatctga aggtatatat aagatgaaat gtgagactgc gggacctatt tttgagttgg
    54061 gacaactaat acctatcgaa tatatagaca aattagaaac agcagaactg acagaaatac
    54121 tgataaatgg agaagatgaa gagagtgagg atagtttaag acaaagatat tatgatagcc
    54181 taaattcaca gagctttggt ggaaatatgc aaaattataa agatgaagtt aacaaaatac
    54241 aagatgttgg aggagttaag gtttatcctg tgtgggacgg tggaggaact gttaagttag
    54301 taataattaa ctctaatttc aaagtaccat cagaggattt agttaattta gtgcaagaag
    54361 aaattgaccc aattggacat caaggacaag gcttaggatt agcaccaatt ggacaccgag
    54421 tcacagttga aggagttaca agtacaacta taaatatatc agcagagata acatacaaaa
    54481 atggctacac ttgggagaat ataaaatcaa ttgcagaaga agcaatagac gactatttaa
    54541 atgaacttaa catgagttgg gaagatgaag aaaacttaat agtccgtata tctcaaattg
    54601 aaactagatt acttagtatt gatggagtat tagacattgc aaatacaatg ataaatgagg
    54661 ttaaatctaa tctaacaata aatagtaaca gtatagtagt gagaggtgag gtagttggat
    54721 aaagagatta atctaataaa ttacttacca caaattctac aagataaaga agaatatata
    54781 aaagtattta atgtaggaaa taaagaaata aaaatattac atgataaatt aaaggaccta
    54841 tcaaatgacc agtttttaga ggacctaact ataagtggta taaaaagatg ggaaaagata
    54901 atgtctataa ctcctaaaag taatgagagt ttagaagata gaaggtttag gatttttagt
    54961 aaatatataa gtaaattacc ttactcagag agatttttaa ggaattggct agatagtata
    55021 gttggagaag gtaattatga gttaactata aataatgcta cttataatat acatttagaa
    55081 agtgatgcta gaaatcaaga ttggtttgag gaagttcatt cttttgtaag tgatattaag
    55141 ccatgcaaca tgacactaga ttacactaga gttttagtta gcaaagataa tagtgtgtac
    55201 tttggagcaa ccactattac agggcatgag attacaattt acccatggtc acctagtgat
    55261 attgaaacac aaggagagat taatatactt agtggcaatg ggtttggata tcaagaggtt
    55321 acaatttatt agataggagg tggtagtttg gctacagata aaagttacta cacgatatta
    55381 acagatatag gtaaggctaa gatagcaaat gcaagtatag taggggaaaa agttgacttt
    55441 gctaggatac aattaggtga tggtggagga aatgagtata atcctacaga ggaacaaaca
    55501 gcattaaaaa atgtagtttg ggaaggtaaa gtagggaatg tcaagactga tgaaagcatg
    55561 acaaattgct taattttaga aagtttaata cctgctagtg ctggtgggtt tgtagttaga
    55621 gagataggtt atttagatac cgaaggtaat ttactagcta tatcaaagta taggtcagca
    55681 tataaaccta aagtggaaga tggagcagta attgacatga aggtaaaaac tatctttgtt
    55741 gtatctaatg taaataacat agaacttaaa attgacccaa ctataatttt tgccacatta
    55801 aaagatttac aggacctaga cactaaaata ggtactgtta atactaaaat agatacaact
    55861 aaggcagaat taacaagcaa catagaaact actaaaacag agctaaacac tagaattgac
    55921 acagaaaatg agaaacaaaa tattaaaatt gaccaattaa tcgcaggtgg ttcaaatgtg
    55981 gcatctactc aaacaataac aattgacgat tgggttgagg atgcagaaaa tggattcaaa
    56041 gcaactgtaa cacatagttt attaacacag agaatagttg taaatattat agatgctact
    56101 acaaaagaaa atgtagttac aaactttaaa attatagatg ataatactat agaaattaga
    56161 agtgaaacaa ggtcagaatt aaacgtttat gtgataaatg gaaatgcaga aactcatttt
    56221 attaatgcaa ctgtagatga taacagagtg tctgaaatga ctacttattc gtctaaaaag
    56281 atacatgaag aaattagtaa ggtagcagaa cagctaacag gaattaatag taatattata
    56341 tctagtataa ataataattt aataccaatg tagaaagtga ggtgataaag tgatagattt
    56401 ttcttatgaa acaagtaaaa ggaaaagaaa aggaatttat tcagagcaag atatatttga
    56461 atcatcacat gtattttatc cagcaggaag aggtagggca gaagcagtat ttgaattaag
    56521 tagtgtaaaa aatatatctg ttacaagaaa tttgaattta tctaaattat caagtgttat
    56581 taatggtgaa aatggagttt tagaaaactt gacaatggag caaaaattag aagttctttt
    56641 tatagataca cctaaaattg aaatatatat ggatgcaaat ataagtaaag gttgtgaaat
    56701 atcatataga atatttgatg actttgcatc aagttatcca tttacagtaa ctgaaaaaat
    56761 taataatgag gttgtttcaa ctaaggttag ttcaaaagat ggaaagtaca ctaccatttt
    56821 aacagatgag cagatattaa aattagaaat tggttctaaa aatactttct taatagaaat
    56881 tagcacagaa ggtggagtag taaccagtaa gcaagcaaca tttacaagaa taaataataa
    56941 accaactatt ttagttaatt catataattc taattctgca aaatttacag catctgattt
    57001 agataataat ttaagtaaaa ttgagtggta tttagatgat gtattaaaag aaacaataac
    57061 aacagattta acagcagaga aaacaataaa ctatgaactt acaaacaatg caatacacac
    57121 attaaaaata gttgctacag acacagaaaa tgcaacagtt gagaaggttt taagtataag
    57181 caaagagatt atgccacttc aatctgatgc aactttacaa gatatatcaa ctaaattggt
    57241 agagattgga gaagggttta aaaatggtaa aacaagtatt ataaatactt tagcattaaa
    57301 gaatatagaa gcaaatctaa ataacacact agttgagttg tcagagaaaa taaaggcatc
    57361 atttgatagt ggagacgcta gtttgcagga tttgatgaac cagttaacac aagctaacaa
    57421 taccataaca cagttaaata caaaatataa agttgcaagt gggactactt ctgttataca
    57481 aagttctcaa catgttaatt tatatggcgg attatatgga gcaacatata ttagacaacc
    57541 atatcattgg attaatatta ataatttagg atttgttcct aatattttta ttgctgaaaa
    57601 tgaaactgtt agcactggta gtgtaattga gaaaaatatt attattgcta cttgtaacat
    57661 gtcttggtct acaaataaaa gagattttat agctaatctt caacttacta gaggtaaaat
    57721 ggatgaccaa gattttaatt gtcatgcagg attttatata aacaatgaac aagatgctta
    57781 tattaatagt aatggaatta atgtacctgc aagtaggact tctcttccta tttatggatt
    57841 ttcttggtat gctataaaat ttaaataaat gaggtgataa aatgaataga gcaaatagaa
    57901 taatttacga ccaaactggt aaaatacttt tacaaactgg agaagcaaca ggagatatat
    57961 tagagcatga tacaataaca gaattacatt atattgatgt tgaatatgga aatatagact
    58021 atagtaaaca gtatatagaa tctataaatc caataacaaa agaacctatt ttaaaagata
    58081 ttccaatcta tttaagcgaa gaagaaaaga gaatacaaga gttagaaaat caattactaa
    58141 ttgcagaaaa tgaaaaagtg ggaggattat tataatgaat ataaataatg ttgtagtaag
    58201 aatattagca gagaggattt taagtagagg cttaaatcct ttaaaaaatc gagaatttga
    58261 attagatgac gtaactaaca cagagtatag aaaagcagta gaggattata taattaaaca
    58321 gagtggagta gtagaaggaa tagaaccaac agcgtagtag gttctttttt ttattgaaag
    58381 aggtgactaa atgactttta aagagttagt taataaagtt agaaatcttg tattagaagc
    58441 aaagaatgta actatagagg atacagagaa taattttaca agtgataatg tagaagatgc
    58501 tttaaaagag gtttttcagt ctggagttga tgctaaaaat aatgtagtaa cagcattaaa
    58561 ctccaaaggt gcagaggtta ctacaaggga tacatgggaa gaaataaaga ataaaattga
    58621 tataaaagag gggagattag atttaagaga aacaacactt tcaaataact attcgtattt
    58681 agttacaaat ggagctataa aatatattga aagatgtagt gggaacttca aaacttttga
    58741 atatgaagaa ccatattttt atgtaattaa agaaactcat ctaattaaaa ttaatgctat
    58801 tgatgaaaca gtagtttttg acattacttt agctaatgct aacttctcat gcatatgtat
    58861 tactcaagaa tatttattta tatctgataa tactaaatta tataaaataa ataagtcaac
    58921 aggaagtgaa gtacagtcaa tagaaggtgc ttattataag ttatgtactt atggggagtt
    58981 tatttatgga gtatatggag atgagacttc ttctacactt cacaaaatta gaatatctga
    59041 tatgtatata atgttaacta aaaatttagt ttctaatggt atttacaatt ttaaaggagg
    59101 taagtttgtt tgcaataaga atgctattta tgctacaaca gaacactcaa attcaagtag
    59161 tattacaaca tgtcatttat ctaaaataaa ttttgatttt gccattgcta aagattttag
    59221 aattggagga tatttgcata tgaaaaacat taagttttta aatgattttg ttattgtatc
    59281 tgatgcagaa agaggtatag aaattgatag caacaaaaaa agtgctttag taaaatatga
    59341 cgcaaattta aatttaattg tgtattcaga cgatagcaaa tatgacaatt ttgatatata
    59401 taatggatat atatatgcta tatattcgct ttctagtagt ccttttgtaa aaataagttt
    59461 aaatactctt aaacatatcg acagctaccg aaaacttact gaaacatacc caaatgctgg
    59521 tatgtttgta ataaatgata tagttttctt tattagtagt ggaattttta gaaatatatt
    59581 gtcaaaaaag gtttattcgg atgagaaagg agaatcatta tgatttattt aggaaattta
    59641 atggatacag aagaacaaaa tataaaatat gttggtatga tacactatga accaaatttg
    59701 ttatcggagg aaaacttaaa acaaggtatt ttgatagaga gtttaccaac tcaaaagtat
    59761 gcagagaata aagaagcaaa gctatttata aatatagata ctaaagaggt tttctataga
    59821 tatacagata ttaaaagtag catagaagat aaagtaaatt ctacagaaca aacaatagca
    59881 gatttaacat ttcaattaat gtcaaatggg gtgatataaa tgaattggta caagataata
    59941 acagatttct ataataatgg taattggact aaagagcaag ttaaaacggc agtagaaaag
    60001 aataagataa cagcaagtga atataaagaa attgtaggag aggactatat agcatagtct
    60061 tttttaattc aaaaattagg aggttttcat gaatgaagaa cttttcgaag cagatttaaa
    60121 aagacatgaa acaagaataa ataaacatgg agaagaaata gacgaattaa aaatagcaaa
    60181 tatagagtct aaagcagagt taaaagcatt gtgtgagaat ctaaactcac ttacaagtat
    60241 gctcaaatgg ctaattggta caatgattac aacacttgta gggttcttta tatttgcagt
    60301 tcaaagagga atattttaat taattaggag gataagagat ggataattta ataagtttta
    60361 taccagagca gttgctaatt ttagtagctg ctctctctat tataggtaaa ggttgtaaaa
    60421 aatataaaca attagataat aaatacattc cagtagtgtt attgatactt ggaatagctt
    60481 tttcagtgtg gatgctagga ttaaatcctg ttgcagtctt acaaggtgta atttgttggg
    60541 gtatatcaat aggtataaat caaacttaca aacagttaaa ggaggaaaac aaataatgaa
    60601 aatagcaata gtaccaggac acactttagg tggaaaagga acaggagcaa ctgggtatat
    60661 agacgaagga aaagaaaata gaatactaac tgatttaatt gttaaatggt tgaaacaagg
    60721 tggagctact gtatatactg gaaaagtaga taaatctagt aattacttag cagagcaatg
    60781 tcaaatagca aataaacaag atgtagacct agctgtacaa atccatttca acgcaaataa
    60841 gataactcta aatcccatgg gtacagagac aatttataaa actaataatg gtaaagtata
    60901 tgctgaaagg gtcaacgaga aactagcaac agtattcgaa aatagaggtg caaaatcgga
    60961 cgtaagaggg ctttactggc ttagacatac aaaagcacca gcaatattaa tagaagtatg
    61021 ttttgtagat agtaaagcag atacagacta ttatatcaga cataaagaca tagttgctaa
    61081 attaatagca gaaggtatat taaataaaaa tataaataat gagggagtta aacagatgta
    61141 caaacataca atcgtttatg atggagaagt tgacaaaatc cctgcaactg tagttggttg
    61201 gggttataat gatgggaaaa tactgatatg tgatataaaa gattacgtgc caggtcagac
    61261 gcaaaatctt tatgtcattg gtggtgcagc atgtgagaag attggttcta tgactaaaga
    61321 aaaatttact atgataaagg gtaatgatag atttgacaca ctttacaaag cattagattt
    61381 tattgataga taaaaggagt atagttaatg tattttacat tttgcttata ctttatgcca
    61441 atattacgac aatttataaa ataaaaaatg atatattaaa gataatcata agccatttta
    61501 aaatccaaaa aactaggtgt ataaacagtt aacaaatata tatattgata aaataatgga
    61561 ggtgaaataa aaaatagtag tgcaataaca ataattctaa tgtagaataa tattaaataa
    61621 tattatttta gggggattta aaatggctta tgaaaatgga actgatttta tagattattt
    61681 tcctgattgt atagaaaaat ataaggaaga taataaaatc tttgagaagg caatattatt
    61741 actcaatctg tatatgcaaa aaccaacatg gccacattgt gttaatgagt acaagagcca
    61801 ggcggaaaaa attttaggtg aagacccaga gtttatagga aagtatggta tacaattaag
    61861 aaaattttat gatgaagatg aaaatgcaaa agtaagtaag gaatttaaaa atgatttgta
    61921 taatttttct aagagtacat atgatatact agataatgtt tatttttcaa aaagtcatcc
    61981 ttttaatctt tcatctattt attcaacttc tagagatgat gattttataa taaaaatatt
    62041 tagatatgat aataattttc ttgaattaga gatgtcaaag agagaagtag agtcattaat
    62101 aaactattta tctgatttat taaaggaaga atagtatgtt aggagcaaaa aaagaaaaag
    62161 agtttaattt attgagtttt aatgaaaaaa agatagaaaa acataaatgt aaaaattatc
    62221 ataatgattc ttcgaaagat aaatacaaat atagtcaaag tgaatttata gctgctactt
    62281 taaaggaggc agatgatatg aatgaagaag aaagaagaat actagaagca gaaaaaagaa
    62341 tattagagac tgagaaaaga gtgcatcaag ataacaagga agtaaaagaa agtatagata
    62401 agcaatttaa tgacataaag ggtattttta aagaatacaa gaatgattta gacaaagata
    62461 gaatagaact aaaaaatgat ttagctagag aaagagctga gttaaaaagt gatttaaaag
    62521 aagctataaa cgaacataaa aaggtcacag aaaaggatgt aagtgaaata aagaatagta
    62581 tgaaaggtat agaagataga attgattcaa ctaataaatg gattattgga ctatgtataa
    62641 ctactataat aggaattgct acaatggcta ttacaatagg tatatctata tggccaaagt
    62701 aacacaaaaa gaggtaacta gaattaaaat agttatctct ttttatactt aaacaaaaca
    62761 ttgaaaaaat agtaaaaaat attaacagga tacataaaac tatagtataa cctgtaataa
    62821 taaaacgaac gaaaattatc atactaaaac ataagacatg ctataattgt attagataaa
    62881 tgcttgaata tataccaaaa gtactctttt tataagagtg cttatttttt tgaaattcat
    62941 caacatataa actatcaaga acattactca acacacctta aaattgattt aaattctttt
    63001 tcatacacaa agttatatga tataataaaa aagtaaatat gtaaccccaa cacatcttta
    63061 ctaagtcaaa cattattata tagagcattc ttcattatgg agagtgcttt ttcatttctt
    63121 tgaataatca tgttgattat ttataatatt ttcatttaat ttatctttat ctatcaaatt
    63181 taatgcacaa ttaatacaaa tgttagtttt catatgactt ttcttatgaa aagtaatata
    63241 cttattatca tctttattta ttcctttatt acagtaatca cataatatag tcttagtcat
    63301 atttttattc ctttc
//
LOCUS       DAMJXI010000016        58908 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.016, whole genome shotgun sequence.
ACCESSION   DAMJXI010000016 DAMJXI010000000
VERSION     DAMJXI010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58908
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.016"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            211..1287
                     /locus_tag="PC465_001381"
     CDS             211..1287
                     /locus_tag="PC465_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2648699.1"
                     /translation="MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLL
                     ALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWP
                     ARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
                     ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIG
                     CIKDNYCADMTRTVFYKEIPEKGREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYI
                     TEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIE
                     DLVLVTEDGCEILNKHDKEICVVG"
     gene            complement(1404..2246)
                     /locus_tag="PC465_001382"
     CDS             complement(1404..2246)
                     /locus_tag="PC465_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDF2648700.1"
                     /translation="MDKIKLIVDSACDLPDDIIEKYNIEVVGLNVSFGEESYISGKEI
                     DNETFYRKMSESKVLPKTSCPSPDKFLEAYHCQEESVLVINISSGLSGTYNSALLAKD
                     MFEKEGNNKKVEVIDSLSGSIGIGQLVLKAAILIKEGKEIEEIVSIINKYKDNPPFFG
                     TLETLENAIKGGRINPIAGKIINTLNFKAIIQVADGVVTPIDKARGEGNSLKKLITLV
                     ESKIKDKEEKVLFIGHANCPEKAQKVREVMEKDVKYKDVVICEIGSVMGTYTSKGAIL
                     ITAI"
     gene            2430..3002
                     /locus_tag="PC465_001383"
     CDS             2430..3002
                     /locus_tag="PC465_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2648701.1"
                     /translation="MKTNNMKQAILSSATNLIAKNGVQNTSLADIAKDVNISKGTLYY
                     HYASKDDIIYDIADTHLEVITSAILNCVKNVKSKNSQIEMVNLILEKISTIESRGRVH
                     MYLICEAITSNNDLKERIRLKYIEWRTTLKSEIVESLEKYNSSKNEQDAESFSFLLMS
                     IVDGLVVQSLLKTEKIPYENIASFLVNHWI"
     gene            complement(3165..3437)
                     /locus_tag="PC465_001384"
     CDS             complement(3165..3437)
                     /locus_tag="PC465_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648702.1"
                     /translation="MLRERFVVRNHHNPHTSGCCGTGGEGCCGGDNHEHSHQHSHSHG
                     HEHEHVNGVGHDHNHDDGFSGTHEHSHEHTHTHGHEHSDGHTHEHK"
     gene            complement(3564..4436)
                     /locus_tag="PC465_001385"
     CDS             complement(3564..4436)
                     /locus_tag="PC465_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2648703.1"
                     /translation="MYGESKKLSIDNNIFLQYCLIILGMILSTLGINLYLAPAKLLSG
                     GVAGICVILYKLFGINQGISSFLMNIPIFIIARKYFDNKFLLISFVNMLLFSLALGLT
                     QDIAKYFPIDDTMLQCIYGGALTGIGMGLTFKARATAGGLDIIAAIMKRKYDIPMKNT
                     FLFINFFVVCAGAFLFGAKLVMYTLITMYIISFTMDIGKDCFDRKKSILLISNKYDEI
                     SKVIMNKMGRGVTFLEAEGAYTQNKKKMIYCIISANEIGKFKDLIYDMDSEAFISVNN
                     VEEVKGGGFKDKFL"
     gene            complement(4732..7839)
                     /locus_tag="PC465_001386"
     CDS             complement(4732..7839)
                     /locus_tag="PC465_001386"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HDF2648704.1"
                     /translation="MAKFKPLVDSSVKQAEAQVFDYWKDINILEKTLEKGKDDPSFVF
                     YEGPPTANGNPGVHHVLSRTLKDSVCRYKTMSGYQVKRKAGWDTHGLPVEIQVEKELG
                     LTSKQQIEEYGIAEFNQKCRESVFSFEKQWRIMTERMAYEVDLDNPYITLDNNYIESV
                     WWILNKFNKEGYIYEGHKILPYCPRCGTGLASHEVAQGYKEVKTNTVIAKFKKKDADE
                     YFLAWTTTPWTLPSNVSLTVNADVDYLKVKKGDEVYYVSKPLADKVLGEDYEVLEEMK
                     GKDLEGLEYEQLMPFVEVDKKAFFITVGDYVTTEDGTGIVHTAPAFGEDDYNTGKRYD
                     LPVIQPVDETGKFTSTPWEGRFVMEDGLDVEIIKWLASENKLYSKEKVVHNYPHCWRC
                     QTPLVYYAKPSWYIEMTKLKDKLIENNNGVKWFPSFVGEKRFGNWLENLNDWAISRTR
                     YWGTPLPIWRCECGHTDSVGSRAELAEKAIEDVNPETVELHRPYVDDIHLKCEKCGKP
                     MTRVTEVIDCWFDSGAMPFAQHHYPFENKENFDQLFPADYISEGIDQTRGWFYSLLAV
                     STFVLGKAPYKSVLVPDLVLDKDGKKMSKSRGNTVNPMELFDQYGADALRWYLLYVSP
                     PWTPTKFDMDGLKEIQSKFIGTMKNVYNFFTLYANTDDINPTEFFVEYKDRPELDRWI
                     LSKFNNLMKDVEENLAIFELNKTLRMIQDFINDDLSNWYIRRSRRRFWATELTEDKKA
                     VYNTTYELLHGLCRAIAPFAPYMSEEMYRNLTGEVSVHLAEYPKCNEELVDTKLEEKM
                     DLAKNLVTLGRASREVERIKVRQPLQKVLVDGKFEDTISDVVDLIKEELNVKEVIFAK
                     DLDEYMNFSLKPNFKEAGPLLGSKMNLFVGALSKLNAHETANKLEKGETLTVDLDGEA
                     FEFNKDLVLIGITAKEGFNVSVENNLFVILDTKLTEELINEGYAREFISKVQQLRKSN
                     NFEVLDNIVIEYCGDDEIAKAVDHFNEYIKSETLALEINRVDDKSLEEQNLNDHMTGI
                     KVIKK"
     misc_binding    complement(7932..8164)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(8339..8866)
                     /locus_tag="PC465_001387"
     CDS             complement(8339..8866)
                     /locus_tag="PC465_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HDF2648705.1"
                     /translation="MLTPIEIENKEFKKGLRGYRDEEVDEFLDIIKEDYESLCRENTA
                     LKEKLGLYQDQVNKYENIEETLKATLITAQSAAEDTCSAANKKAKIIVEEADLKARQI
                     IEQANNRVIEIRKEYDALVKEFKIFRNKFKSLLEDEIRSVDEIFYDVDEKCVNAFEGT
                     TVYNYSNDEAATTLE"
     gene            complement(8901..9686)
                     /locus_tag="PC465_001388"
     CDS             complement(8901..9686)
                     /locus_tag="PC465_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HDF2648706.1"
                     /translation="MDKLKLTNHIKDIDLKNKMFKVIDKANSCIKNYDVKSTEFLNPY
                     EVKNAVAILNSTNEIKYSVDGGYERAERSTVFIYPFYMEYEDIEDTLRFLQIEGNFKF
                     KNISHKDYLGSILGLGIKREKIGDIIIHDSFCQVVVSSDICDFIIVNLEKVSRNNVIV
                     KEISRENIVNSSSKYKEVSFTVSSDRLDCVISGIYNISRQDSAKYINGEKVHVNYEKI
                     TSTSKIVKNDDLISIRGKGRAKVTQIGDITKKGKIKVQARLIV"
     gene            complement(9696..9953)
                     /locus_tag="PC465_001389"
     CDS             complement(9696..9953)
                     /locus_tag="PC465_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HDF2648707.1"
                     /translation="MGTIRIALYYLLDIIAWMIVIKSLMTWFPNGRQSKIFDILENLT
                     EPIEGPIRSIMYKYTNGPIDFSPLIAIVLLMFLRQLVLVIF"
     gene            complement(9972..10430)
                     /locus_tag="PC465_001390"
     CDS             complement(9972..10430)
                     /locus_tag="PC465_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HDF2648708.1"
                     /translation="MSNGIISKFKNWIVDEEEDYIEDEYESGMDDIVQEEEMNSGFST
                     TKANKIVNLHTTSQMKVVIVEPKVYDEAATIADHLKQRRAVIVNLEGLTNSEVRKSIF
                     NFMNGAVYVLDGSIQKVSKSIFILAPNNVDIDANMKKELESKAFFPWQNK"
     gene            complement(10470..11174)
                     /locus_tag="PC465_001391"
     CDS             complement(10470..11174)
                     /locus_tag="PC465_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HDF2648709.1"
                     /translation="MGSIKDNLSEIRNKIDKAAKKVDRDSKEITLLAVTKTVDVDLVN
                     EAMREGITSVGENKPQELARKYDIIGDKLNWHLIGTLQTNKVKYIIDKVCMIHSLDRI
                     ALCEEIQKRAEQINREIDCLVQVNISKEESKHGLDREEVVDFVKEVSEKYKNIKIKGL
                     MTMAPFIEDEDEIRGVFKGLKDLSKQIKELNIPNVGMDVLSMGMSHDYEIAIEEGATI
                     VRVGTSIFGERNYNKK"
     gene            complement(11184..11819)
                     /locus_tag="PC465_001392"
     CDS             complement(11184..11819)
                     /locus_tag="PC465_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648710.1"
                     /translation="MKKVKYTRLVILGILIYLVFNILVMIISKNVNTLVLKNEKVDAK
                     IHVKGSIEKDANDQSNYLSTYISKEDSNNFEKNQNVIIEYHEQKLDAKVYKIYENNNK
                     IMVKLKISNQIVANQDTSVEEFDIIYNQMECLKIPKTSIKTKDNKRGVYVIDEQSQSV
                     KFVILEGITYENESSVFVDYYKNDINGVTSVNLYDKIILRPNSINTNIRIK"
     gene            12200..13240
                     /locus_tag="PC465_001393"
     CDS             12200..13240
                     /locus_tag="PC465_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2648711.1"
                     /translation="MSEILLGTGLLLLVLCCFTIFSYKAPYGMKAMGALANAACATFL
                     VEAFNLSLLGDVLGMEFFRSVGAANGSLGGVAAAILVPLALGVSPVYAVLIGLSCLDF
                     SILSGFVAGYFVSFLIKFIEKKVPPGVDLVVVILLCAPLSRLIASNVDPLVNSTLLQI
                     GQVLIEATNISPIIMGIILGGLITVVGTSPLSSMALTSIIGLTGLPMAIGALGAFGSA
                     FMNSTLFAKLKLGSKKDIISVAIEPLTQSDIISANPIPIYSTNFFGGAFSGIIVALMG
                     LVNMTPGTATPVAGFAIMFAYNPVQQVLITAGLCALFNVIAGFLGSKIFSTFKVLTAG
                     EIRGTDVEEEIA"
     gene            complement(13703..15058)
                     /locus_tag="PC465_001394"
     CDS             complement(13703..15058)
                     /locus_tag="PC465_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009170073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HDF2648712.1"
                     /translation="MNVGNILETIKMIDEEQLDIRTITMGISLLDCIDPDGDKAREKI
                     YNKIMSSAKDLVKVGKDIEREFGIPIVNKRVSVTPISIIAGATDENDYVKFAQTLDKA
                     AEDLGIDFIGGFSALVQKGYTKGDKILIKSIPKALASTNKVCASVNVGSTRCGINMDA
                     VKEMGEIIKETAELTKDAKGFGCAKLVVFCNAVEDNPFMAGAFHGVGEADRIINVGVS
                     GPGVVKRALEKVKGEPFDVVSETVKKTAFKITRVGQLVAKEASSRLDVPFGIIDLSLA
                     PTPAIGDSVANILEEMGLEVVGTHGTTAALALLNDAVKKGGVMACSHVGGLSGAFIPV
                     SEDAGMIDSVIKGALSIDKLEAMTAICSVGLDMIAVPGNTTAGTLGAMIADEAAIGMI
                     NNKTTAVRIIPAPGCDVGDMVEFGGLLGRAPVMPINTNSSELFTQRGGRIPAPIHSFK
                     N"
     gene            complement(15084..15353)
                     /locus_tag="PC465_001395"
     CDS             complement(15084..15353)
                     /locus_tag="PC465_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDF2648713.1"
                     /translation="MKAILTVIGKDKPGIVAGISDELYKQNINIVDISQKILQDYFTM
                     IMIVDLEKSLNSFEKTVEDLVERGKKLSVDVKIQREEIFNSMHNL"
     gene            complement(15642..17612)
                     /locus_tag="PC465_001396"
     CDS             complement(15642..17612)
                     /locus_tag="PC465_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648714.1"
                     /translation="MKKYEIFIFMSIIVLCFISFPHKVFGQEENCLEDFERWVQENKN
                     NKEEIVYTLSCDMVIDEEFRFYIPYDSNFTIDTNKYKILIKNHGRFIIDDNELNIIGE
                     GGKEGVIHIENGGSISIGINNIIATDGTALYVEEGGDLHIKSSYESVEKIKANGKDAI
                     GIYTENDIRILNKDIEVNGEHAIGVYSKGDVEIEETSIKAYSSNNESGLLRDNNKLAQ
                     SIISESKKVYIIDDYNELIPSIAEDSGYDIVKCCHRGIGVFSDEIKVSKDDKIENIKF
                     PKYMVLETSSGNRLDIDVEWDFTDYYEKLEKGENFNITGKFKTEMLNKEKIIINDDVV
                     PILNVSVIEKKPIDNLELEFQNTKNGYVAVLFYDMPYSASKVFVEYSSDGINWISEEQ
                     EDIRDQAILFFEDFKLRCFRVKVVGGLKEGYSNIVFKPGFIMGGGDNQETPDDEREND
                     DIDGDRGGGGRDDPDRDEDDNNQDGNNGNENNDSNNNQNNNNENNNNENNNNENDNSD
                     EKQPNTPKDDVESSTDSNENKNPHDIPKDGNKENNSDKEKGFYNKNSITENDDNYDLS
                     SKSVFGTNEHSFPYRESISNKNQDTNKNKSNISDYDGIINNNYKLESKEYNLKKDIIF
                     LFCILTPIMIGSILIVNPDTRKSIIKFIKLKK"
     gene            complement(17795..19270)
                     /gene="spoIVA"
                     /locus_tag="PC465_001397"
     CDS             complement(17795..19270)
                     /gene="spoIVA"
                     /locus_tag="PC465_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage IV sporulation protein A"
                     /protein_id="HDF2648715.1"
                     /translation="MNNNIYEDISKRTQGDIYIGVVGPVRTGKSTFIRKFMEKLVIPN
                     IDNEFKKDRTRDEIPQSGSGKTIMTVEPKFVPADGVEIKIKDTVSLKVRMVDCVGYIV
                     EGALGHEEGGKQRLVSTPWSQEAMTFEKAAEIGTKKVIKDHSTIGIVVLTDGSVTGID
                     RKSYVEPEERVIQELKNLKKPFAVVLNTLSPKSEETSMLRSELEEKYEVPVLPMNVVE
                     MEEEDIEEVMEAVLYDFPLTEIRINLPKWVEGLERNHWIKSSIITTLKQSIIDIGKIR
                     DIEGIIQGFSELEFLEDTGVDNVELGEGVINIDLQTKQDLFYNVLEEKSGFKIEGDYQ
                     LLSLITRLSKVKNEYDKIESALIDAKIKGYGVVAPSLEELSLEEPEIMKQGKQYGIKL
                     KANAPSLHIIKADISTEVSPIVGNQNQGEEMIKYLMEVFEEQPADLWESNMFGKSLHD
                     LVKEQLQSKLYTMPEEIRVKMQKTLQKIVNEGSSNIITILL"
     gene            complement(19442..20737)
                     /locus_tag="PC465_001398"
     CDS             complement(19442..20737)
                     /locus_tag="PC465_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2648716.1"
                     /translation="MSVEVNKPSIWKNFKVLIILFVAGAFIYALPYLKNYYYDTFAQA
                     FNLTNTQMGSLGSIYGLLAMVSYLFGGFLADRISARKLLSGSLIITGISGLVLTLYPP
                     YIVVFLIHALWGITTILTFWPALVKAVRMLASENEQGKAFGFMESGRGITNAIHLSLV
                     LILFGYISSKVSDKSGLTAIIVLYSAINVIVGVLVFFKLKDNEKEVSAKFDKEAFFAV
                     IKMPHTWIITIIMFCSYSANMSFYYFTPYSTEAFGATVVFASAISILAQYCRPVASAA
                     SGLLGDKVGSSKIISYGFILMIAGLLGVIFTPTKSSMIYILLIGCVAIYVSMYAIQGL
                     HYSLLEEGNYSLSISGTAIGIVATLGYLPEVLCPLAAGKILDAFPGVTGYRYYFIVLT
                     IVAIIGLVFTFIWMNMTKERRKELIEMNNNSNENTTKVS"
     gene            complement(20921..22330)
                     /locus_tag="PC465_001399"
     CDS             complement(20921..22330)
                     /locus_tag="PC465_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2648717.1"
                     /translation="MKKKIGFWDLVFMNISALFGIRWIAKSTASSFGLGLGSIPVWLL
                     FAFIFFVPASLICAELAATYPKDGGLGEWVKQAYGEKWGFMVSWLNWTSKIFWYSSFL
                     TFLAINIAYMLGNPDLSNNKMFILALSLIIFWLLSLVSTRGMAFGKFFTNTGALGSTI
                     PAILLIVMAFMSVVILKKAPSASIYTIQNIIPKIDANSLVSISAIIFALSGAETTANF
                     ITEMDNAKKNFPKAILTVAVLIGGIYILGSVAITMILPPDKIAASTGILDALAKVAQD
                     LGIGSWFIRIVAFGITLSVLGALILYIAGPVKMLFGNVREGVFPKQLTVTNKYNIPSN
                     AVIVQAIIVSLLLVGTNLLPSVDNIYNVLVTMTALTALFPYVLLFTSYIRLRKTRPNE
                     ERPYSIAKSDSVCINIARMVLVVTVVGILFSTAPVMETLKDNIIYEIEMIGGGLFVII
                     TGLMLWKNYEKKISNNSGR"
     gene            complement(22382..23521)
                     /locus_tag="PC465_001400"
     CDS             complement(22382..23521)
                     /locus_tag="PC465_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2648718.1"
                     /translation="MSNNMRLERLRKYMNEKSIEIALIFEPDNQFYISGFKAITYSRP
                     IVTVVTQDKIELIVPGLEELHAKEVAKVDNVYVYYEIPEMKEHGISHKHYLDIILNKY
                     PKGTTVGIEKDIVSASFSEYITDKSFAIKDVGSKIFEMRYVKDAKEIEFLKIAGYLSD
                     IGIKGSLENVRVGMSELEFDVAGDNALLKYVSENYPDTYIGFANWTCSGIDRTAQPHL
                     DSNTRILQRGDIVIHSRQVWYENYRAENERTFIIGKPTERQKEVFKIAVEAQQAGLDT
                     IKAGIPARMVDEAARAVVAKYGLELYSNHRIGHGLGLSEHEEPYLRFDNELILEEGMV
                     FSMEPGIYIPGVGGFRHSDTAIVGKNGATIITNYPRSVEELILDI"
     gene            23840..24490
                     /locus_tag="PC465_001401"
     CDS             23840..24490
                     /locus_tag="PC465_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2648719.1"
                     /translation="MTNKELQKKRILMYFIEAAQNIMENEGIENITLRKVADMAGYNS
                     STLYKYFKNLDHLISFASIKYFKDYNLNISRCIENVNDEYKKYIIMWKLFCKHSFDNA
                     QAFYQVFFNLSSDELSYITKQYYDMFPEDLGIHDSDISLMITGESIKERNKILLNNLV
                     DTGYIPAKDLDIINDIIISFYQNLLFLKKNTGKNSDDDELTMKMISSIEYIIKHAK"
     gene            complement(24647..25666)
                     /locus_tag="PC465_001402"
     CDS             complement(24647..25666)
                     /locus_tag="PC465_001402"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HDF2648720.1"
                     /translation="MEKVCVLGTGSWGSALALGLAKKGNDVSMWTRKEEQAKKINRTK
                     ENTDYLPGVLFPNNITISTDIEKTIKDCKVIVLAVPSQAVRSTCQKIKPFIKEGQVIV
                     NVAKGLEKGTGLRLSQVCEEELPQNPYVILSGPSHAEEVARDIPTTVVVASKDLKIAQ
                     MIQDLFMSPKLRVYTNPDIVGVELGGALKNIIAFGAGICDGLGYGDNAKAALMTRGIS
                     EMSRLGIAMGANMSTFAGLSGIGDLIVTCTSMHSRNRRAGILIGKGMSLEDTLKEVKM
                     VVEGITATEVAHDVSEKLDIDMPITNAIYSVIKKGSNPKEVGIELMMRSKKHEMEEVV
                     LGDDI"
     gene            complement(25697..26311)
                     /gene="plsY"
                     /locus_tag="PC465_001403"
     CDS             complement(25697..26311)
                     /gene="plsY"
                     /locus_tag="PC465_001403"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HDF2648721.1"
                     /translation="MEIFSYIIIAVVAYLLGNISTSYIVAKRIAGVDIRTQGSGNAGS
                     TNVLRTLGKRAGAMTFLGDVLKGVMAVLISEFAARLVGIDTLLAGYLAVICVVAGHNW
                     PAVLGFRGGKGVATSLGAMLAVNPVITLMCLAVFILVVAITKYVSLGSVVGIGCSPIF
                     MIMVKNKAGLIVALFLTASVIYNHRANIKRLLNGTERKIGQKKE"
     gene            complement(26346..27665)
                     /gene="der"
                     /locus_tag="PC465_001404"
     CDS             complement(26346..27665)
                     /gene="der"
                     /locus_tag="PC465_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HDF2648722.1"
                     /translation="MSRPVVAVVGRPNVGKSTIFNKFAGKRISIVENTPGVTRDRIFA
                     EVEWLDKYFTLVDTGGIEPDSEDIILSQMRNQAMLAMDMSHVILFIVDGKAGITAADK
                     EIAQLLRKTKKPVILVVNKIDSQSQFDNIYDFYELGFGTPFAVSGANSMGFGDLLDEI
                     VENFPAGLDTEYEEDIIRVAITGKPNAGKSSILNKILGEERVIVSPIAGTTRDAIDTY
                     FEKNGQKFLLIDTAGLRRKSKIYETIEKYSVIRAMSAVDRADVVLIVIDALEGVTEQD
                     TKVAGIAHDEGKGCIFVINKWDLIEKDNKTMSNYTKDIKEKFPFMMYAPIVFVSAKTN
                     QRMNKILDTVEYVSNEHSKRISTSALNEVIGEAVMLNQPPSDKGRRLKIYYGTQTDIR
                     PPKITLFINDKDLTHFSYQRYLENKIRENFGFEGTSIKFEYRQKNKK"
     gene            complement(27699..29027)
                     /locus_tag="PC465_001405"
     CDS             complement(27699..29027)
                     /locus_tag="PC465_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF512 domain-containing protein"
                     /protein_id="HDF2648723.1"
                     /translation="MEVNVKKVNNIISKVYKDSIAEEMGIEVGDLLISVNEQPIHDII
                     EYRFLLSDEYLDVEIQKKDGEVYIYEIEKDYDEDLGVEFTNPIIDQAKSCRNKCMFCF
                     IDQLPEGMRETLYFKDDDSRLSFLQGNFVTLTNMSEEDINNIIKYRISPINISVHTTN
                     PELRQKMISNKFAGKLYGIMKRLADAHIEMNCQIVLCPGINDGKELDRTIKELAQLYP
                     YVNSVAIVPVGITKHRENLVELNIFNDKSASKTIEQIHQIQQKYLEKLGTRFAFLSDE
                     FYILSNSELPGYEEYEGFLQFEDGVGMIRKLKTEIEEYLNILPENILKREKKVSIATG
                     HSAYEFIQSMADAMMDKFKNLQVNVYEIKNKFFGETITVSGLLTAKDLKEQLEDKELG
                     EALYITRSMLKADEEIFLDNIELNQLEELMRIKIIPCLNEGKDFVDKILK"
     gene            complement(29265..29465)
                     /locus_tag="PC465_001406"
     CDS             complement(29265..29465)
                     /locus_tag="PC465_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648724.1"
                     /translation="MGMDIGLNEYTLAIVTLDKNMKNGGGCPIFYANDEKDLQNKALL
                     MSKCVGGMVHDMTNGTLIIVKH"
     gene            complement(29467..30399)
                     /locus_tag="PC465_001407"
     CDS             complement(29467..30399)
                     /locus_tag="PC465_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HDF2648725.1"
                     /translation="MDRVFFVAVIIGITSRIIMLNLDQKQYPTQPNVLLSQLILAFVA
                     SSLGALLVPALINRSYTSITFLSLAAEQFRQVRANRRNTLQNLEEVQLVKRGAAFIEE
                     IARTYEVRNYMCIVTSFLTIGLYYVILAETKISEGMSLVISSICGLVLAFILKKLLTR
                     KSIGDIADVMPAEISFVDESILKVGDLKGITNIGLKSDREVYINRGVGIQIIPKNKDY
                     ANAGILFDSGQRQAIVYNIYSRLGLYGDYGEPSFVPLPRRNKEDESIMIAYLPVDKNV
                     EKVMEAVKSCPILSSSKGKNLSLKNYKIGKKGSA"
     gene            complement(30444..31376)
                     /locus_tag="PC465_001408"
     CDS             complement(30444..31376)
                     /locus_tag="PC465_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HDF2648726.1"
                     /translation="MEESLLNANLFRHSFIVALVVGILCRGLVLRVTDKQYPSRPQDY
                     LEQIIISGLSASLGAIALPALIDKEFAALTFFAVAIQQFQGLAEQERITLKNIDNEEL
                     VPKGDAYVEEIASTYESRSYISLFSALVSSIVYIVFARKYGLSFFYCTILAIVSGAIV
                     GLIFRRFLRRNSIADIADIVPAKISFEGPILMVNGVIITNIGLESTREKYRNECLAIE
                     VIPRDLGAFGIVNDIGQRQAIIHNLFIHMGIDRDVDEVDIVAISKTNLEKSTVVIPYM
                     PILKDIDVMIDVVKSTPIIETSKGKQSDFSRKTL"
     gene            complement(31431..32720)
                     /locus_tag="PC465_001409"
     CDS             complement(31431..32720)
                     /locus_tag="PC465_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2648727.1"
                     /translation="MEDLNSIYFFIVMLSIAIVILAVRYTITLRKYLKEFIYISKKVS
                     NNEYHARLNISAKGELGELARNFNHMIKNMDKTLEEVQYKHLQLRSILKSISHGILAI
                     DVNGNILLINDEAKEMIKSEPNQLVEGHNINVVIKEEEILKQILQFIGSKDNETANIT
                     TKDDIVYKIKVDPVYLQNTNNVIIGSIVNIEDITKKVKLENMRSDFVANVSHELKTPL
                     TSISGFVETLKSNENIDVNTRNRFLEIIESESDRLKRLIDDILLLSFVENKDTLLMEN
                     VVVYDVFKEVYEITQHSASEKNIEVLYKCDDKSISILSNKDYIKQVFLNLVDNAIKYT
                     QDNGIVQVVVLKDEEKIVIKVIDNGVGIPKEDVERIFERFYRVDKARSRDVGGTGLGL
                     AITKHIVKSLNGCIKVKSELGIGSEFIVTILQKNFLK"
     gene            complement(32749..33441)
                     /locus_tag="PC465_001410"
     CDS             complement(32749..33441)
                     /locus_tag="PC465_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2648728.1"
                     /translation="MNTKVLVIDDEMHIVELLKFNLEVSNYEVSYSYDGFDGFIKAKE
                     IKPDLILLDWMLPNISGIEVLRKIRSDKDLKNIPVIMLTAKNMENDKVEGLEIGADDY
                     ITKPFSIKELLARISSVLRRYNLTSLGEENNILTTGNLKLDLSKHEVTKGSEKIELTL
                     KEFELLKLLIQNKGKVLSRNYLLDKIWGYEYYGETRTVDVHIRYLRKKIEDEDKSEKY
                     IETIRGVGYKID"
     gene            complement(33456..34217)
                     /gene="pgeF"
                     /locus_tag="PC465_001411"
     CDS             complement(33456..34217)
                     /gene="pgeF"
                     /locus_tag="PC465_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HDF2648729.1"
                     /translation="MMKDYINIKNVQDIKEYVNLSGNCEELDEKLNSVNLVITCKNID
                     AKNREDMLKVCKECDLTFENLTSNSQIHSDIVNIVNKDTIGKRRDGDALITNLEKVPL
                     LLFTADCVPISIIDAKNKAIGLAHAGWRGTFSNIGHKTIKLMSECYKTVPEDLVCIIG
                     PSIGPCCYEVSEDLVEKFNTILTNNDEKFYIIKEGSYYLDLWKINEYMLRCSGVKKEN
                     IINLNLCTSCRADKFHSYRKHNKASERIGTVLQIK"
     gene            complement(34214..34675)
                     /gene="nrdR"
                     /locus_tag="PC465_001412"
     CDS             complement(34214..34675)
                     /gene="nrdR"
                     /locus_tag="PC465_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HDF2648730.1"
                     /translation="MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIE
                     TTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIDEIESIVVHIENEINKCFIEEI
                     ETKKIGEMVMDKLKELDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK"
     gene            complement(34697..34960)
                     /locus_tag="PC465_001413"
     CDS             complement(34697..34960)
                     /locus_tag="PC465_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HDF2648731.1"
                     /translation="MIRVSDIMEKEIINVKNGKRMGFIIDIDMDIHEGKVVSFTIFGD
                     GSRSFFSRGGDEEVIFWNDILKIGCDTIIVNIGSELSLDEFEI"
     gene            complement(35064..35837)
                     /gene="sigG"
                     /locus_tag="PC465_001414"
     CDS             complement(35064..35837)
                     /gene="sigG"
                     /locus_tag="PC465_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigG"
                     /protein_id="HDF2648732.1"
                     /translation="MQVNKVEICGVNTSELPVLKNKQMKELLLQIKNGDEEARQQFVR
                     GNLRLVLSVIKKFNNRGENIDDLFQIGCIGLIKAIDNFDLSQNVRFSTYAVPMIIGEI
                     RRYLRDNNPIRVSRSLKDIAYKALQVRERLIRTNSKEPTVSEIAKELELEVESVVMAL
                     DAIQDPISLFDPVYQDNGDAIFVMDQVQDKKDTDENWLQEISLKEAIKKLNSREKLVL
                     DLRFYKGRTQIEVADEIGISQAQVSRIEKNALKNMRKYV"
     gene            complement(35929..36651)
                     /gene="sigE"
                     /locus_tag="PC465_001415"
     CDS             complement(35929..36651)
                     /gene="sigE"
                     /locus_tag="PC465_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigE"
                     /protein_id="HDF2648733.1"
                     /translation="MLRLKERIISFITMLGIKLKIIKPKGIYYMGGANILPPPLKPEE
                     EMELLQKLETDESVKSILIERNLRLVVYISRKFENTGIDVEDLISIGTIGLIKAVNTF
                     KLNKNIKLATYASRCIENEILMYLRKNNKKKTEVSFDEPLNIDLDGNELLLSDVLGTE
                     NDEIYKIIEEEIDRDLLVMALDRLSDREKQIMELRFGLIDKGIEKTQKEVAGMLGISQ
                     SYISRLEKKIISRLQKEMKKFV"
     gene            complement(36676..37548)
                     /locus_tag="PC465_001416"
     CDS             complement(36676..37548)
                     /locus_tag="PC465_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E processing peptidase SpoIIGA"
                     /protein_id="HDF2648734.1"
                     /translation="MFKGFKGGYMVYIEYYVIENLVINYIIISCTSILTKRYNPKKNK
                     LLGASLGGAYSVAYLYPSMNILFTVPFKIIIMSIITLISFRSKSKKDYVHVALVFYLV
                     NIFISGSTYFIIYFTGISHLKISFLIACTYVSCELLKYIYKDLKMLKYIKELTKTINI
                     NLLEKSFCCKALVDSGNLLKDPISQSDVIIVKSSVLEGFIPEKLLNINYEDIDMKKAQ
                     EIIGSLDDKTSGRVRIIPYKHAGSNKTSIIIGLKADYIEVDEQKIGNIILGISNFNDR
                     EYGAIMNPNILPGF"
     gene            complement(37838..39112)
                     /locus_tag="PC465_001417"
     CDS             complement(37838..39112)
                     /locus_tag="PC465_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDF2648735.1"
                     /translation="MIKLKKVLSLVMVGILSVSILAGCSKKEDSKGKEGKEKLVVWSA
                     PLTDHDADAWKPIFEKFEKENNCEIEFQIVPWDNYAEKYATAISAGEGPDIGYMYAEM
                     FPQFIEMGAVEDLTPYLEKSGTSDNYLYLDDAKMMGGIYGLPIEAANPGVLYYNKDIL
                     EKLGEKPPKTWDDFKRICEKATKDTDGDGKIDQWGLAQGWGSKVFGSLNWNWYPYLWQ
                     AGGDIYNDDLKSVKFNNAEGLKAANFINDMKKYIPEDALSKDSNEMIESVFGPGKAAF
                     TIMLSSAATSTFDKSFPDLNWGYVTSLEDKTVGSFASVDDLTLMSACKNKELGFKLLE
                     YMLSKESMEAFHKEIPRAPVAKGEKYQGDPRFEEMVTRDKHMYRPLTVGPHGVEIYEY
                     LWKQLQMMIAGDITPEQALNESAKYANGLLAQ"
     gene            complement(39396..40553)
                     /gene="ftsZ"
                     /locus_tag="PC465_001418"
     CDS             complement(39396..40553)
                     /gene="ftsZ"
                     /locus_tag="PC465_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HDF2648736.1"
                     /translation="MLNFDVELEECAQIKVIGVGGGGNNAVNRMVEAQLKGVEFISVN
                     TDKQALYTSKAEYKVQIGEKLTRGLGAGANPEVGKRAAEESKDEIVKLLQGADMVFVT
                     AGMGGGTGTGAAPVVAGLAKEMGILTVGVVTKPFAFEGKIRMKNAEGGIAELKSKVDT
                     LITIPNDRLLQIVQKNTSMLDAFAVADDVLKQGIQSISDLIAVEGLINLDFADVTTIM
                     KDKGLAHMGIGSASGETRAIDAARQAIQSPLLETSIQGAKGVLLNVTGGPNLGLFEVN
                     EASTLVMESCDPEANVIFGASIKEDLGDEIMITVIATGFEGLQNGALDLDTKPKSSIR
                     SSLNTTVKQAVKEIEEEVIAEEKIEPPKKASIIEEDDDESMEIPTFLRRRR"
     gene            complement(40743..41096)
                     /locus_tag="PC465_001419"
     CDS             complement(40743..41096)
                     /locus_tag="PC465_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small basic family protein"
                     /protein_id="HDF2648737.1"
                     /translation="MLWVLGGLAFGVVVGYYIPFTYSMDYSIYMSVAILAIMDSIFGA
                     IKSNFEDNYDNVIFITGFIGNAILAILLTYIGEKLGVSLYYVAVLVFGMRLFNNLSII
                     RRYIISNIMNKKRKN"
     gene            complement(41195..41869)
                     /locus_tag="PC465_001420"
     CDS             complement(41195..41869)
                     /locus_tag="PC465_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HDF2648738.1"
                     /translation="MKKKIVILGAFILGVFISTYIKSLDPNRVYITLGQTESIESEVE
                     NTKKEIKNLKETLKKNKKTLNEYKEAKKNGNESIQTLMQKELEEVKELSGYSTITGPG
                     ITITMRDSERELKDGQNPNDLIIHDIDILRVLNDLKKAGARAISINGERVLATSKIKC
                     SGATITVNDTTYGQPFIIKAIGDIDLLSAAINSPESYAKSLKDIYGINIKVQENNGNK
                     VNLFAK"
     gene            complement(41874..42572)
                     /locus_tag="PC465_001421"
     CDS             complement(41874..42572)
                     /locus_tag="PC465_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HDF2648739.1"
                     /translation="MKKRFINKSIIIGSIVLGVLVSLQLKIINIENRGMTTFKRGEQL
                     TEELKSLKKEKENLQSEVNSVKKDIETYRGKNNEGEQDILKSEIEKYETLAGYTDVEG
                     TGIKIEINSTKDLGNSDKNDSILYNYDLLLSMINKLNSAQASAISINDQRIVSNTYMY
                     LKEDKLYMNDTVIKEPIIIKAIGDSDTLASALNIKYGIVWEIETYYNAKVKVTKEDNI
                     EINGHSDINKAEGK"
     gene            complement(42595..43335)
                     /locus_tag="PC465_001422"
     CDS             complement(42595..43335)
                     /locus_tag="PC465_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HDF2648740.1"
                     /translation="MKKRRKLNTNNVMIVLVFILMLSFCICIIVKSDLFDVKKIDVIG
                     NKRVTKSNIMKELNVNLNENIFAYNFKDMKNKLIKNPYIENVEIKRKLPNKIIISLKE
                     KEIFAVLKDEDNYCYIDKKGNLLEELRGSNESKKDLIVDVDYSIDDNKSIKFKNYKTK
                     ENVFKTLNYLKEEGIYRKINYVNLKKESNIEMLTRSNIKILLSNDDNLDYNISRVSKI
                     LIDLQNKNTNGGTINLNYGKLAVYSPEG"
     gene            complement(43605..44831)
                     /gene="murG"
                     /locus_tag="PC465_001423"
     CDS             complement(43605..44831)
                     /gene="murG"
                     /locus_tag="PC465_001423"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDF2648741.1"
                     /translation="MKVLLSGGGTGGHVYPAIAIANKIRDEHPDAEIIFVGTEKGIES
                     EIVPKYGFELKTVTVQGFKRKIDFDNVKRVFKLFKGLEQSRKIVKKFKPDIVIGTGGY
                     VSGPVLFNASMGKIPAIIHEQNSFPGVTNKILSKTVTKVLTSFEDSHKRFPEAAEDKL
                     VFTGNPVRKEILLSRKNIARKNLSISDEKRMVLCYGGSGGSRKINDAMRLVIKNMVNE
                     DIAFIFATGKSYYDEFMGSISDINLKPYQKVVPYLEDMANALAASDLVIGSAGAISLA
                     EITALGKPSIIIPKAYTAENHQEYNAKSIEKQGAGIAILEKNLTPESLNTAVFKLLGD
                     RELLVDMANASKTIGKPEAIDLIYDEIMKVYNSTQKSTSKKTKKEKVIKEVKEIKKET
                     TPSIEGQAKVIGIKKR"
     gene            complement(44849..45979)
                     /gene="spoVE"
                     /locus_tag="PC465_001424"
     CDS             complement(44849..45979)
                     /gene="spoVE"
                     /locus_tag="PC465_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein E"
                     /protein_id="HDF2648742.1"
                     /translation="MPKENLKKQIDIRMKTEFDGVVFYTTMLLVFVGIVMVFSASFIQ
                     SSFKHNDAYYFLKKNVIYAVLGFIVMIITSRIDYSFWKKNATAIGAIAVVLLLLVLTP
                     LGIEANGAKRWLGIGALTFQPAEIAKFATIILTAKLIEKNYDKIKSLTKGVVPLLVVP
                     GIFFALIILQPNLSTAGTVILVTFVMIFVAGMDMKIVFAMIGSGAALFAALVIAEPYR
                     LSRVTSFLDPFQDPLGKGYQVIQGLYALGSGGLFGLGLGKSKQKYFYIPEPQNDFIFA
                     IIGEELGLIGCIIVIMLFVVLVYRCVRIALKTSNVFACMVVIGIGAQIGIQAALNIAV
                     ATSSMPATGVALPFISYGGTSLTIFMGAVGIVLNISKHVKIN"
     gene            complement(46031..47386)
                     /locus_tag="PC465_001425"
     CDS             complement(46031..47386)
                     /locus_tag="PC465_001425"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HDF2648743.1"
                     /translation="MDLKGKKVLLVGLAKTGISTIKHLDKLGASIIVNDIKDENKLRN
                     ILDELKSINDIKYILGHHPEDVDDIDMVVVSPGVPLDLPFILKLKNSGKYIIGEVELA
                     FKLSNNPIFIGITGTNGKTTTTSLVGEIFSRAKRDTYVVGNIGNPVIDTIETSSEESV
                     LVTELSSFQLESIDEFRPKVSAILNITEDHLNRHHTMEKYIEAKANIFMNQTVEDFCV
                     LNYDDEIVKSLADKCNAKVIYFSRTKKVNGGVYLENNDIIIDIDDKIKFLNKDDVSLP
                     GGHNLENCMAAIAIAYVCKIDLEVIKDVLMTFKGVEHRQEFVRNLDNVIYVNDSKGTN
                     PDSTIKAIQSYDRPIILIAGGMDKGSNFDELLETAKSYVKSLVLLGETASNIENCAKN
                     KGFNDIHIVKDMEEAVKTSYEISKSGDIVLLSPACASWDMYESFEVRGKDFKDNVNNL
                     K"
     gene            complement(47405..48373)
                     /locus_tag="PC465_001426"
     CDS             complement(47405..48373)
                     /locus_tag="PC465_001426"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HDF2648744.1"
                     /translation="MMLGITELTYTALIAFLIVIIIGPIFIPMLRKFKFGQTVRDDGP
                     QTHLAKNGTPTMGGIIMIVAILITGLTRVKVSHDMAVGLICIAGFGFIGFLDDFIKIK
                     LKRSLGLKAYQKIILQVALSFYVAFYQYTSSSSASQLMIPFTDFVINVGILYIPIMMF
                     IIVAIVNAVNLTDGLDGLASGVTLIVSVFFMLFASSIAGNTEVAVLAAATVGACLGFL
                     GFNSYPARVFMGDTGSMALGGAVVAFSVLTNSVLIIPIIGGIYFAEALSVLIQVGYFK
                     ATRKRFFKMAPIHHHFEQCGWPETRVVFIFWIITVVLAWISIIAVF"
     gene            complement(48414..49787)
                     /locus_tag="PC465_001427"
     CDS             complement(48414..49787)
                     /locus_tag="PC465_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HDF2648745.1"
                     /translation="MECLTIKELVLATNGKLIYGDYNDCVSDIVIDSREANAQNAFVA
                     IVGENLDGHTFMKSAYDSGCKTFIKNESNGIKLESSDINLIEVKDTSLALGDISKYYK
                     EKFDIPFIGVTGSVGKTTTRDMIYSAISAKLNILKNEKNLNNHFGVPLTLFNLNKEHE
                     CAVIEMGMSGFNEIKYLVDIVNPKIAVISNIGLSHVEKLGSQEGILKAKMEITSNFDE
                     TNTLIVNGDDKFLSTLKEKEHAYKLKTFGFNKNNDVYCESYTMEEDSLTFICVINGKK
                     EEIFIPTIGEHNIYNAMSAILVGLCLNISLDYIKKGLKNFKGTKMRLDIIKNEKLTII
                     NDSYNASPDSMDAALKILGRYKGRRVAILGDILEMGEISEYGHRLVGKSSMNNTDIII
                     TIGENSVFIGEEAKQLGFNSANIYHFENREDVFNKLNELVKTGDTILVKGSRGMRLEK
                     IVEYLNK"
     gene            complement(49954..51933)
                     /locus_tag="PC465_001428"
     CDS             complement(49954..51933)
                     /locus_tag="PC465_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein D"
                     /protein_id="HDF2648746.1"
                     /translation="MRKVKRISKKRLVLVLILACALFFCLVIRTGYLQLMKGNWLSTK
                     ALEQQTRDIPIEPKRGTIYDRNMKELAVSVTKYTVWCKPVEVEDKKEAAEKVAEILDE
                     DYKDIYALISKKNMALVKVKRWIDDDKASQIRDAKLSGIWVAEDNQRYYPYGNFAPYV
                     LGHTSSDATGISGVEMQYDKKLKGKPGKLIVSTDASGREIPQGMEKYYEPVQGNGLVL
                     SIDEVIQHYTEKAVQKAYELNNAKKVTAIAMNPKTGDILALASKPDYDPNDSRTPIYP
                     YYQEELEKYNDKDKIKGYYQMWRNPAVSDTYEPGSTFKLITSSSALEEGVIKDGEKFT
                     CTGSVTVGGRKIKCWRHYRPHGTQEFKQAVQNSCNPVFVELGSRLGVGKMYDYIESFG
                     LMDKTGIDLPGEAKGILYNEKNVGPVELATISFGQSISVTPIQLITAISSIANGGDLM
                     QPRVVKSYTDNKGNITETVKPKKVRSVISKETSKKMLEIAESVVTEGGGKIAYIPGYR
                     LGGKTGTAQKVIDGKYAPGKYICSFVGIAPCDDPQIVVLAIVDEPTGVSAFGSTTAGP
                     IVKEIMNDSLKYLGVKPVYKEEEKAEYEKKQVKVPDVRNLKIGDAVKALEDAKLKPDL
                     DADIELPEDTKVKDIFPKPGVKVNEDSSITLYFEN"
     gene            complement(51945..52292)
                     /locus_tag="PC465_001429"
     CDS             complement(51945..52292)
                     /locus_tag="PC465_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648747.1"
                     /translation="MKKNYKIHNLNEYKNKKKNNYKKRNKKKIGAKCILLIATFSVII
                     LNLCGYSKISEMKYDIYYLQKDLRKKEIVLEELKAKETEKTSIKEIELKAKELLNMDY
                     PKDGQIKYIDVDN"
     gene            complement(52774..53709)
                     /gene="rsmH"
                     /locus_tag="PC465_001430"
     CDS             complement(52774..53709)
                     /gene="rsmH"
                     /locus_tag="PC465_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HDF2648748.1"
                     /translation="MEFHHVSVLLNECIENLNIKPDGVYVDCTMGGAGHSKEIVKKLS
                     DKGLFIGFDQDKNAISTAKERLSEYESRVKFVHSNFENIKEELEKIGVYKIDGVLADL
                     GVSSHQLDEADRGFSYMQDAPLDMRMDVRCEFSAYDVVNTYTEDELTKIIKDYGEDNW
                     AKRIAKFIVEERANKPIETTGELVDVIKKAIPKKARIDGPHPAKRTFQAIRIEVNNEL
                     GVITKMINDASSIMNEGGRICIITFHSLEDRIVKNAFKHLASDCICPQHLPICQCDKE
                     SEVKIITRKPILPSEEEIEVNPRSRSAKLRVAEKI"
     gene            complement(53739..54485)
                     /locus_tag="PC465_001431"
     CDS             complement(53739..54485)
                     /locus_tag="PC465_001431"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HDF2648749.1"
                     /translation="MDRVAFTLFGIDIMWYGILMACGMILGTLIAIKEAKRVGIKEDD
                     VLNIAIIAIPVGLICARIYYVVFNWSYYAQNMSQIFNFRGGGLAIHGGLIGGILAGYI
                     YTKIKNINFLKMADTVILGMPLAQAIGRWGNFINGEAHGGATNLPWGIMVDGVKVHPT
                     FLYESIWDFGIFIVLLLFRKNKKYEGQVIVTYITLYSIGRFFIEGLRTDSLMLGPLRM
                     AQVISLIGVIGGIIAHVYLSKKNKNNISEE"
     gene            complement(54879..56165)
                     /locus_tag="PC465_001432"
     CDS             complement(54879..56165)
                     /locus_tag="PC465_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDF2648750.1"
                     /translation="MEKIVNDILKEEVYYEKLQNGLDVYFMPKRGFMKKYAILATNYG
                     SNDLEFVPIGEDKKIRVNEGIAHFLEHKMFEQPDGGDAFDKFSKLGVNANAFTNFTMT
                     AYLFSATENFYESLEHLIDYVQTPYFTDENVEKEKGIIAQEIKMYNDDPDWNVYFNCL
                     KAMYVNYPARIDIAGTVDSIYKITKEELYKCYNTFYNPGNMALFVVGDLDVEKVIDVT
                     KKSNNYKVDRLSKSIERFYPEEPEGVKEKEVIEKFPISMPMFNIGFKDSNVGLKGKEL
                     LRKEIVTDILVGMLFKKGSKLYEDLYMQGLINENFGAGFSSQVDYAFSIIAGDSKEPK
                     KVKEIILDYIEKSKKEGLSKEEFERTKKKKIGSFIKCFDSINFIGNSFISYVFKDINL
                     LEYLDVIKDITFEEVEERLKEHFKEEYCVISIVEPK"
     gene            complement(56180..57445)
                     /locus_tag="PC465_001433"
     CDS             complement(56180..57445)
                     /locus_tag="PC465_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDF2648751.1"
                     /translation="MVNTKKIINLGNNINLTLIKTEKFKSNLISLYVQRLLDEKETTK
                     NALIPSIIASGSAKYPSARAISNKLDDLYGSSMGADAVKRGERQVLSFKVINISEKYL
                     DESIFEEVVEFFNEVINNTLVVDGGFKEEYLNIEKENLREKIQSIINDKKEYAQDKCI
                     EAMCKGERYSVSEFGYEDEIDSITSRELYEHYKNILKTSPIDIVVEGNFDEDKVVDII
                     SKNLKFEREEIINIPRADFIKNVDEVKVIDEQMEITQGKLVMGYRANVDYADIDKYYA
                     LVVGSNVLGGGPHSKLFVNVREKESLCYYIFSSIEKYKSIMFISSGIETKDYDKAVEL
                     IKKQVESVKAGDISDEELENSKLALVNSMKSITDNIGGMSDFVFSQSMAKTNSEVQDI
                     ISSIEKVTKKDIVEAIKNIELDTVYFLRN"
     gene            57761..58858
                     /gene="ychF"
                     /locus_tag="PC465_001434"
     CDS             57761..58858
                     /gene="ychF"
                     /locus_tag="PC465_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HDF2648752.1"
                     /translation="MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSV
                     PDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVV
                     RCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
                     LLKSIMSTLEESKCVRTMEFTEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNK
                     YVQQVKAFAETEDAEVVVVCAQIEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSY
                     ALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIRAETIAFNDLVEHGT
                     MAAAKEKGLVKLEGKEYIVKDGDVILFRFNV"
BASE COUNT        18466 a        10670 c         6339 g        23433 t
ORIGIN      
        1 ataactttat agacttaatt tattactttt atagaatttt cacaataaaa agtcatttta
       61 cttccgtatt taatgcaaaa gtagagatta aacttaatat aaaaaatata taacaaattt
      121 tttttatatt tctagaagaa aagtatactc ttttttgttt aataatgcta aaattgattt
      181 gtattgaatt ttgattagga ggaaattatt atgaaagctc aaagattaaa tgctgtactt
      241 gaacaaatga aaaaagatga tatttctcaa atgttagtaa gtgaccctac ttctatattt
      301 tatcttacag gagtactaat ccatccaggc gaaagactat tagcattata cttaaattta
      361 aatggcaata ataaattatt tataaatgaa ttattcccag tttcagaaga tttaggtgtt
      421 gaaatggttt ggtttaatga tactcaaaat ccagtagaaa taataactga acatatagac
      481 aaaaatgcta ctatgggtgt tgataaaaac tggccagcta gattcttatt aaacttaata
      541 gaattaggtg gaggaagtaa gtttgtaaat tcatcttata taatagatac tttaagaatg
      601 tgtaaagatg aagaagaaaa agagttaatg agaatagctt caaaattaaa tgacaaggct
      661 atggaacaac ttaaagctac tgtttctggt gaacttacag aaaaacaact tgttggtaaa
      721 ttatctaaaa tatatgaaga cctaggtact gatggatttt catttgaccc tattataggt
      781 tttggaccta atggagctaa tccacatggt gaacctggaa atgcacttgt gaaaccagga
      841 gatgcaataa tcttagatat aggttgtata aaagataact attgtgctga tatgacaaga
      901 actgtattct ataaagaaat acctgaaaaa ggtagagaaa tatttgaaat agttcttgaa
      961 gctaataaga gagctgaagc tattgtaaaa ccaggtgtta gattctgtga tatagatgct
     1021 gctgctcgtg actacataac tgaaaaggga tatggacagt acttcactca tagaactggt
     1081 cactctatag gacttgaagt tcatgataaa ggagatgtat cttctataaa tacagatact
     1141 gtacaaccag gaatgatatt ctctatagag ccaggtatat atttaccagg tgagttcgga
     1201 gttagaatag aagatttagt acttgttact gaagatggtt gtgagatatt aaacaaacat
     1261 gacaaagaaa tatgtgtagt tggttaattc taaaatcaat ttgataaaat taaaaagcca
     1321 tataaaaatg ttttaaacat ttttatatgg ctttaatttc tcaatctatg atttatttca
     1381 atccattatt tatattgcag tatttatatt gcagttatta agattgcacc ctttgaagta
     1441 tatgtcccca tcactgaacc aatttcacag attacaacat ctttgtattt tacatccttt
     1501 tccataacct ccctcacctt ttgagctttt tctgggcaat tagcatgtcc tataaataaa
     1561 accttttctt ctttatcttt aatttttgac tctactaaag taatcagctt tttcaaactg
     1621 tttccttcac ctcttgcctt atctatagga gttacaacgc catctgcaac ttgtattatc
     1681 gccttaaaat tcaaggtatt tataattttt cctgctattg gatttattct accaccctta
     1741 atagcatttt ctaaagtttc aagtgttcca aaaaatggag gattatcttt atatttattt
     1801 attattgaaa caatctcttc aatttctttt ccttctttta ttaatattgc tgcttttaac
     1861 actaattgtc ctattccaat tgacccacta agtgaatcta taacctcaac tttcttgtta
     1921 tttccttcct tttcaaacat atcttttgct aaaagtgcac tattataagt cccagataat
     1981 cctgaactta tattaatcac taatacactt tcttcctgac aatggtatgc ttctaaaaat
     2041 ttatcaggag aaggacatga tgtttttggt agtactttac tctcactcat ttttctatag
     2101 aaagtttcat tatctatttc ctttccagat atataacttt cttctccaaa agatacattt
     2161 aaaccaacaa cttctatgtt gtatttttct attatatcat caggtaagtc acatgcactg
     2221 tccactatca attttatttt atccatatta acctcactat aagatattat tttatttatt
     2281 cagtcggtcg tacgaccgat ttaattatta ttttatatat tgaatgaaaa aaagtcaata
     2341 gatatagatt ctcgctttat tgacaataaa tatccataag cttataatgt tattaatttg
     2401 ttataaatat acatggaaag gtaggtttta tgaaaacaaa taatatgaaa caggctattt
     2461 tatcatctgc aaccaattta atagccaaaa atggagttca aaatactagc cttgctgata
     2521 ttgcaaaaga tgtaaatata agtaaaggta ctttgtatta tcactacgca tctaaagatg
     2581 atattatata tgatattgcg gatactcatt tagaagttat aactagtgct atactaaact
     2641 gtgtaaaaaa tgtcaaatca aaaaattctc aaatagaaat ggttaactta atcttagaga
     2701 aaatatctac tatagaaagt cgtggtaggg tacatatgta tcttatttgt gaggcaatta
     2761 cttcaaataa tgatttaaag gaaagaataa gattaaaata tattgaatgg agaactactc
     2821 ttaaatctga aattgttgaa tcactagaaa aatataatag tagcaaaaat gaacaggatg
     2881 ctgaatcatt ttcttttttg ctcatgtcaa tagttgatgg tttagttgtc caaagtttat
     2941 taaaaacaga aaaaatacct tatgaaaata tagcttcttt tttagttaat cattggattt
     3001 aaacttaata cttagataat taataaaagt gaactattta agttatctac tttaacagtt
     3061 cactttctta tttattctca ataattttta cttaaaacat tcaattttta tttaaacctt
     3121 catggaatca caaaataaaa atctcttata aatttaaaat gtttttattt atgttcatgt
     3181 gtatgcccat ctgaatgttc atgaccatgt gtatgtgtat gttcgtggct atgctcatga
     3241 gtacctgaaa aaccatcatc atgattatgg tcgtgaccta caccatttac atgctcatgt
     3301 tcatgcccat gactgtgaga atgttgatgt gaatgttcat ggttatctcc tccacagcat
     3361 ccttctcctc cagtcccaca acacccactt gtatgtggat tatgatgatt tcttactaca
     3421 aatctttctc ttaacataat tcttatacct cctagtatat tattgagtac ttcatgtacc
     3481 ccattaacta cagtatacat ctaactaggt ataatctcaa tacatatggc attttttaac
     3541 atatataatt aacatatata atcttaaaga aatttatcct taaaacctcc accttttact
     3601 tcttcaacgt tattgacaga aataaaagct tcactatcca tatcataaat taaatcttta
     3661 aatttaccta tttcatttgc agatattatg caataaatca tctttttctt attttgtgta
     3721 tatgcacctt ctgcctccaa aaaagtgact cctctaccca ttttattcat tatcactttg
     3781 gatatttcat catatttatt tgatattaaa agtatagatt tttttctatc aaagcaatct
     3841 tttcctatat ccatagtaaa agaaattata tacattgtaa ttaaagtgta catcaccaat
     3901 ttagctccaa ataaaaaagc tcctgcacat actacaaaaa aattaataaa taaaaatgta
     3961 tttttcatag gtatatcata ctttcttttc attatggctg ctattatatc aagtcctcca
     4021 gcagtagctc ttgctttaaa agttaacccc atacctatac cagttaatgc accaccataa
     4081 atacactgta gcatagtatc atctattggg aaatatttag caatatcttg tgttagcccc
     4141 agtgctagag aaaatagtaa catattgaca aaacttatta gcaaaaattt attatcaaaa
     4201 tactttctag ctataataaa tattggtatg ttcatcaaga aacttgatat tccctgattt
     4261 ataccaaata atttgtataa tataacacaa attccagcta ctcctccact taataacttg
     4321 gctggtgcta gatataaatt tattcctaag gttgatagaa tcatacccaa tataataaga
     4381 caatattgta aaaatatgtt attatcaata cttagctttt tactttcacc atacatcaaa
     4441 acgcacccct ttgcataata aataaaccac cctgcagaac acacgataaa tttacaaata
     4501 aatttatcag aagtagctta ctaaaaatat tattcatcct cacttaaacg tttattcatt
     4561 aatattctat cacatgacat aaataattta tatgatttat atagatttat ttattgtaaa
     4621 ttttggaata ttaaaatatt ttattgaata gataattata ttacataaaa aatccctata
     4681 gaaatctata aactaatttc tatagggatt ttggttaact aactattctc tttatttttt
     4741 tataactttt atacctgtca tatggtcatt taagttttgt tcctctaaag atttatcatc
     4801 tactctgttt atttctaaag ctaaagtttc agacttgata tattcattaa aatggtcaac
     4861 agccttagca atttcatcat caccacagta ttctattact atattatcta atacttcaaa
     4921 gttattagat tttcttaatt gctgtacttt agatataaat tctctagcat aaccttcatt
     4981 aatcaactct tcagttagct tagtatctag tataacaaaa agattgtttt caacagatac
     5041 attaaatcct tccttagcag ttatacctat taatactaaa tccttattaa attcaaaagc
     5101 ttcaccatct aaatcaactg ttaaagtctc acctttttca agtttattag cagtttcatg
     5161 agcatttaat ttacttaatg ctccaacgaa taaattcatc ttagaaccta ataatggccc
     5221 tgcttcctta aagtttggtt ttaaactaaa gttcatatac tcatctaaat ccttagcaaa
     5281 tattacctct ttaacattaa gctcttcttt tattaaatca actacatcac ttattgtatc
     5341 ttcaaactta ccatctacta acactttttg taatggttga cgaactttta ttctttctac
     5401 ttctcttgaa gctctaccta aagtaactaa gtttttagct aaatccattt tttcttctaa
     5461 tttagtatct actaactctt cattacattt aggatattca gctaaatgaa cagatacttc
     5521 tcctgttaag tttctataca tttcttctga catatatggt gcaaatggag ctatagctct
     5581 acaaagacca tgtaacaatt cataagttgt attgtacact gcttttttat cttctgttaa
     5641 ttcagttgcc cagaatcttc ttcttgaacg tcttatatac cagttagata aatcatcatt
     5701 tataaaatct tgtatcattc ttaaagtttt atttaactca aatatagcta aattttcttc
     5761 tacatctttc attaaattat tgaacttaga taatatccat ctatcaagtt ctggtctatc
     5821 tttatattct acaaaaaatt cagttggatt tatatcatct gtgtttgcat ataaagtaaa
     5881 gaagttatat acattcttca tagtacctat aaatttactt tggatttctt ttaatccatc
     5941 catatcaaat ttagttggag tccatggtgg agaaacatat agtaaatacc atcttaatgc
     6001 atctgctcca tattggtcaa ataattccat tggatttact gtatttcctc ttgatttact
     6061 cattttctta ccatctttat caagtacaag gtctggaact aaaacactct tatatggtgc
     6121 ttttcctaat acaaatgttg atactgcaag taatgagtag aaccaacctc tagtctggtc
     6181 tataccttct gatatatagt cagctgggaa caattggtca aagttttcct tattttcaaa
     6241 tggatagtgg tgttgagcaa atggcatagc cccactatca aaccaacagt ctataacctc
     6301 tgttactctt gtcattggtt ttccacattt ttcacatttt aagtgtatat catctacata
     6361 tggtctatga agttcaactg tttctggatt tacatcttct atagcttttt cagctaattc
     6421 agctcttgaa ccaactgaat ctgtatgacc acattcacat ctccatatag gaagtggagt
     6481 tccccaatat ctagttcttg atattgccca gtcatttaga ttttctaacc agtttccaaa
     6541 tctcttctct cctacaaaac ttgggaacca ttttacacca ttattatttt ctattaattt
     6601 atctttaagt ttagtcatct ctatatacca gcttggtttt gcatagtata ctaatggagt
     6661 ttgacatctc cagcagtgtg gataattatg aactactttt tctttgctat ataatttatt
     6721 ttcagaagct agccatttta ttatttcaac atctagccca tcttccatta caaatctacc
     6781 ttcccaagga gtagatgtaa atttaccagt ttcatctact ggttgaataa ctggtaaatc
     6841 atatctttta cctgtgttgt agtcatcttc accaaatgct ggtgctgtat gaactatacc
     6901 agttccatct tcagtagtta cataatctcc tactgtaata aaaaatgctt ttttgtcaac
     6961 ttctacaaaa ggcattaatt gttcatattc taaaccttct aggtctttac ctttcatttc
     7021 ttctaaaact tcataatctt cacctagtac tttatcagct aaaggtttag atacataata
     7081 tacctcatca ccttttttaa cttttaaata atctacatca gcatttactg ttaatgaaac
     7141 gtttgatggt aaagtccatg gagttgttgt ccatgctaag aagtattcat cagcatcttt
     7201 tttcttaaat ttagctataa ctgtattagt ttttacttct ttatatcctt gtgcaacctc
     7261 atgactagca agaccagttc cacatcttgg gcaataagga agtattttat gtccttcata
     7321 tatatatcct tctttgttga atttgtttag tatccaccat acagactcta tatagttatt
     7381 atctaaagtt atatatggat tatctaaatc aacttcataa gccattctct cagtcattat
     7441 tctccattgt ttttcaaatg agaaaactga ctctctacat ttttggttaa attcagctat
     7501 tccatattct tctatttgtt gcttgctagt aagacctaac tctttctcta cttgtatttc
     7561 aactggtaat ccatgtgtat cccaaccagc ttttctcttt acttgataac cagacattgt
     7621 tttatatcta caaactgaat ctttaagcgt tctagataaa acatggtgta ctccaggatt
     7681 tccattagct gttggaggtc cttcatagaa tacgaaactt gggtcatctt tccctttttc
     7741 taaagttttt tcaagtatat ttatgtcttt ccaataatca aaaacttgtg cttctgcttg
     7801 ttttacagaa ctgtctacca atggcttaaa tttcgccatg taaatcaccc tttcctacta
     7861 aatattataa ttccaaaatt ttttattctt tcacataaat ttaaatacta aaaaactcgc
     7921 cccctttaaa ccaaagggac gagttataaa tcgcgttacc accctaattc tatatgtaaa
     7981 ctaaatacta gctacatata acactctaat agtataacgg tactaaccgg cacagcttag
     8041 tagaatttaa tcgttcagcc tgcagctcaa gagtgatttt tatctttata aattcattgg
     8101 ttctcagcat acccaattct ctgtaaaatt atctaaagat aaatgtctct atcaacgctt
     8161 ttaaaaattt atctgtgttt atatgaaatt ctataacaaa taatttgaat agtcaatata
     8221 tttttgaaaa atataataat ttctattttt cttacatttt tatcctattt ttaatctttg
     8281 ttatagattt ctcaaactca cacaattatt ctacataaaa aataaacaaa ttacaagctt
     8341 attctaaagt tgtagcagct tcatcattac tataattata cactgttgtt ccttcaaatg
     8401 cgtttacaca tttttcatct acatcataaa aaatctcatc aacacttctt atttcatctt
     8461 ctaacagtga tttaaattta tttctaaata tcttaaattc tttgactaaa gcatcatact
     8521 cttttcttat ctctataaca cggttattag cttgttctat aatttgtcta gcttttaaat
     8581 cagcttcttc aacaattatc ttagcctttt tattagccgc actacaagtg tcttctgctg
     8641 cactttgagc agttattaaa gtggctttta gtgtttcttc aatattttca tacttgttta
     8701 cttggtcttg atataaccct aatttttctt taagagctgt attttcccta catagagatt
     8761 cataatcttc cttgatgata tctaaaaatt catcaacctc ttcatctcta taccctctta
     8821 aacctttttt aaactcttta ttttctatct caattggagt tagcattaca tttcctccca
     8881 gctataattt aaattagtcc ttatacaatt aatcttgctt gaacttttat ttttcctttt
     8941 ttagtaatat ctcctatttg tgttacctta gctcttcctt tgcctctaat agaaatcaaa
     9001 tcatcatttt ttactatttt agaagttgaa gttatctttt cataattgac atggactttt
     9061 tctccattta tgtattttgc actatcttgt ctagatatat tgtaaatacc acttatcaca
     9121 caatctaacc tatctgaaga tactgtaaat gatacttctt tatattttga agaactatta
     9181 acaatatttt ctctggaaat ttcctttaca attacattat ttcttgaaac cttttctaag
     9241 tttacaatta taaaatcgca aatatcacta cttacaacta cttgacaaaa gctatcatgt
     9301 ataattatat ctccaatttt ttctcttttt atacctagac ccagtattga ccctaagtaa
     9361 tctttatgag atatattttt aaatttgaaa ttcccttcta tttgtaaaaa tctaagagta
     9421 tcttctatat cttcatattc catgtaaaat ggataaataa atacagtgct tctttcagct
     9481 cgttcataac ctccatccac actgtatttt atttcatttg tagaatttaa tattgctaca
     9541 gcatttttca cttcatatgg attaagaaac tccgtagact taacatcata gttttttata
     9601 caactattag ccttgtctat cactttaaac attttatttt tcaagtctat atcctttatg
     9661 tgatttgtta gttttaattt atccatccta tcaccttaga atataaccaa tactaattgt
     9721 cttaggaaca tcaataatac tattgcaatt aaaggagaaa aatctatagg tccatttgta
     9781 tatttataca ttatagacct tattggccct tctattggct ctgtaagatt ttccaaaata
     9841 tcaaaaattt tactttgtct tccatttgga aaccaagtca tcaagctttt tataactatc
     9901 atccatgcta ttatatctaa aagataataa agtgcaattc ttattgttcc catatattaa
     9961 ccgccttttt actatttatt ttgccaaggg aagaatgctt tactttctaa ttcttttttc
    10021 atatttgcat ctatatccac attattagga gctagtataa atattgattt agaaaccttt
    10081 tgtatacttc catctaagac ataaactgcc ccattcataa agttaaatat agatttacga
    10141 acttcagaat tagtcaatcc ttccaaattc actataactg cccttctttg ttttagatgg
    10201 tctgctatag ttgcagcttc atcataaacc ttaggttcaa ctattacaac tttcatttgg
    10261 ctagttgtat gtaaatttac aattttattt gcttttgtag tactaaagcc actgttcatt
    10321 tcttcttctt gaactatatc gtccatgcca ctttcatatt catcttcaat gtaatcttct
    10381 tcttcatcaa ctatccaatt cttaaattta gatattattc catttgacat tattaacttc
    10441 ctccttaaaa tttattcaaa tttgagtaat tattttttat tgtagtttct ttctccaaag
    10501 attgatgttc caactctaac aatggtagcc ccttcctcta tagcaatttc ataatcgtga
    10561 ctcattccca ttgacaaaac atccatccct acattaggga tgtttagttc ttttatttgt
    10621 tttgataaat ctttaagacc tttaaataca cctcttatct catcttcatc ttctataaaa
    10681 ggtgccattg tcattagacc ctttattttt atatttttat atttttctga cacttctttg
    10741 acaaagtcta caacttcttc tctatcaagt ccatgcttag actcttcttt agatatattc
    10801 acttgtacta agcaatctat ttctctgttt atttgttctg cacgtttttg aatttcttcg
    10861 cataatgcaa ttctatctaa agagtgtatc atacaaactt tatcgattat gtacttaact
    10921 ttattggttt gcaaagttcc tatcaggtgc cagtttaatt tatcacctat aatatcatac
    10981 tttctagcta attcttgggg tttattttca ccaacagaag tgattccttc cctcattgcc
    11041 tcattgacta agtctacatc aacagtcttt gtgactgcca aaagggtaat ctctttgctg
    11101 tctctatcta ctttttttgc agctttatca attttgtttc ttatctcaga caaattatct
    11161 ttaatagaac ccattattat cacctacttt atccttatat ttgtgtttat actgttaggt
    11221 cttaaaatta ttttgtcata tagattaaca cttgtaactc catttatgtc atttttataa
    11281 taatccacaa atacagaaga ttcattctca taagttattc cttctaatat gacaaatttt
    11341 acactttgtg attgttcatc aattacatat acaccacgtt tattgtcttt tgtttttata
    11401 gaagttttag gtatttttaa acattccatc tgattatata ttatatcaaa ttcttcgaca
    11461 cttgtatcct gatttgcaac aatttggtta cttattttta attttaccat tattttatta
    11521 ttattttcat atattttgta aacttttgca tctaattttt gctcatgata ttcaattatt
    11581 acattttgat ttttttcaaa gttattagaa tcttctttac tgatgtatgt agatagataa
    11641 ttactctggt cattggcatc tttttctata cttcctttta catgaatctt tgcatcaact
    11701 ttttcatttt ttaacaccaa cgtatttaca tttttgctaa ttatcattac taatatatta
    11761 aatactaaat atataagaat accaagtatc actaatctgg tatattttac ctttttcaaa
    11821 gactctcccc ctataaaatt actttcatta taagtacttc ttctaaaaaa tgtttattcc
    11881 ttttttataa gctaatattt tacgttctaa taattatttt ttccatatta aatttatttt
    11941 ttatcaatct tcctatacaa gactgcatta tttatatata attgtattat aaagtataag
    12001 tttaatttac attttatacg ttaagcttac tttatatgtt tttatagtta tttttatttt
    12061 tagatacaat ataaaaccaa ttaagattta aaataacttt tgttatgttg acatttattt
    12121 aggtaatcat ttacgaatca ggataacgtt atcataacaa aagtttatgt cctaaaaaaa
    12181 atacaaggag gattttctta tgtcagaaat tttattagga acaggtttac ttttattggt
    12241 tctatgttgt ttcacaattt ttagttacaa ggccccatat ggtatgaagg ctatgggagc
    12301 tctagcaaac gctgcatgtg ctactttctt agtagaggca ttcaaccttt ctttacttgg
    12361 tgatgtttta ggtatggaat tttttagaag tgttggagct gctaatggta gtcttggtgg
    12421 agttgctgct gctatacttg tgcctttagc cttaggtgta tctccagttt atgcagtttt
    12481 aataggatta tcttgtttag atttttctat attatctgga ttcgttgctg gatactttgt
    12541 ttctttctta attaagttta tagagaaaaa agtgccacct ggagtggatt tagtggttgt
    12601 aattcttcta tgtgcaccac tatctcgtct tatagcatca aatgtagacc cattagttaa
    12661 tagtacacta ctacaaattg gacaagtttt gatagaagct accaacatta gccctataat
    12721 aatgggaatt atactaggag gtctaataac agtagttgga acgtctccac ttagttcaat
    12781 ggctcttaca tctataattg gtcttactgg tcttcctatg gcaataggag cattaggtgc
    12841 ttttggttca gcttttatga actcaacact atttgcaaaa ttgaaattag gttctaaaaa
    12901 agatattata tctgttgcta ttgaaccatt aacccaatca gacataattt cagctaatcc
    12961 aatacctata tattctacta atttctttgg aggagccttt tctggtatca ttgtagcctt
    13021 gatgggtctt gtaaacatga caccaggtac agctacacct gtggctggtt ttgctataat
    13081 gtttgcttat aatccagttc aacaagttct tataacagct ggtttatgtg ctttattcaa
    13141 tgtaattgca ggatttttag gttcaaaaat attcagtacc tttaaagttc ttactgctgg
    13201 tgaaatacgt ggtactgatg tagaagaaga aattgcttaa aaaacaataa gatttataaa
    13261 tttatatctc aagtagtaga gttttatatt gtaggcaatt ttattaattg caaacgtttt
    13321 attttttatt tatgtttatg attattatgt gtgttgaata tttagataaa tttttattta
    13381 ttatttttat ttagattttt gtttagtttt ttatttggtt gatatattag gaataaaaat
    13441 tagtatagtt tattactagt tagatagcat aactttttag atacataaaa aattttatat
    13501 taattagata ttattaaaat aaaagcgata catgaatttt taaatgtcca tgtatcgctt
    13561 tatttttgcc ataatcttaa caactaattt ttaaagttta ttatcttaac aaagttcatt
    13621 atcttatata atatttaaat gcatagactt ctttaattta accatctaaa tatttaatta
    13681 aatattatta tatgtaatat aactaatttt taaatgaatg tataggagct ggaatccttc
    13741 ctcctctttg agtaaataat tcagatgaat ttgtatttat aggcattact ggtgctcgtc
    13801 ctaaaagtcc tccaaattct accatatcac ctacatcaca tcctggggct ggtataattc
    13861 taacggctgt agtcttatta ttaatcatac ctattgctgc ctcatcagct atcatggctc
    13921 caagcgtacc tgctgtagta tttcctggca cagctatcat atcaagacct acagaacaaa
    13981 tagcagtcat tgcttcaagc ttatctatac ttaaagcacc tttaataaca gaatcaatca
    14041 tacctgcatc ttcagatact ggtataaacg ctccactaag tcctccaaca tgtgaacatg
    14101 ccattactcc acctttttta acagcatcat ttaaaagtgc taatgctgct gtagtcccat
    14161 gagtaccaac aacttcaaga cccatttcct ctaatatatt tgctactgaa tcaccaatag
    14221 caggtgtagg agctagtgat aagtctatta tcccaaatgg aacatccaat ctactagaag
    14281 cttcctttgc cacaagttgt ccaactcttg taattttaaa tgcagtcttt ttaactgttt
    14341 ctgaaacaac atcaaaaggc tctcccttta ctttctctaa agctctctta acaacaccag
    14401 ggccacttac accaacattt ataattctat cagcctcacc aacaccatgg aaagctcctg
    14461 ccataaatgg attatcttct actgcattac aaaatactac taattttgca caaccaaaac
    14521 cttttgcatc ttttgttaat tctgcagttt cttttatgat ttctcccatt tctttcactg
    14581 catccatatt tataccacat cttgtagaac ctacatttac tgaagcacat actttattag
    14641 tacttgctag agcttttgga attgacttaa ttagtatctt atcacctttt gtatatccct
    14701 tttgaactaa tgctgagaat ccaccaataa aatctatacc taaatcctct gcagccttat
    14761 ccaatgtctg tgcaaacttt acatagtcat tttcatctgt tgcacctgca ataatggaaa
    14821 ttggagttac tgataccctt ttatttacaa ttgggatacc aaattcacgc tctatatctt
    14881 ttccaacctt caccaaatct ttagcagaac tcataatctt attgtatatt ttttctctag
    14941 ctttatctcc atcagggtct atacaatcta ataaagaaat ccccatagtt atagttctta
    15001 tatccaactg ttcttcatct atcatcttta ttgtttcaag tatatttcct acattcacta
    15061 ttatcacctc cccttactgt ctactacaga ttatgcattg aattaaatat ttcttctcgc
    15121 tgaattttta catccactga taatttctta cctctttcaa ccaagtcctc aaccgttttc
    15181 tcaaaagaat ttaatgattt ctctaaatca actatcataa tcatagtaaa ataatcctgt
    15241 aatatttttt gtgatatatc tactatgttg atattttgct tgtataattc atcactaatt
    15301 cctgccacta tacctggttt atcctttcca attactgtta aaattgcttt cataataata
    15361 tcctccctta tttttttata aatcttatat ttttacaaat tgaactatgt gttaacatat
    15421 atttcattta tttgttagta aaccactttt tatgtatata tttaatatat tttaatacct
    15481 atacattcat ttgtcaattt ttttcaatat tctattattt ttatactatt tagaaaattc
    15541 atatattata tatgttttct caacaacaaa tacagttttc ataataatga aaggtattac
    15601 ttagcaatct catgattttc taaataatac ctttctaaaa attatttttt taattttatg
    15661 aatttaatta tactttttct agtatcagga tttacaatta atatagaacc aatcataatt
    15721 ggtgttagta tacaaaataa aaaaataata tcttttttta gattatattc tttagattct
    15781 aatttataat tattatttat tattccatca taatcactta tatttgactt atttttattt
    15841 gtatcttgat ttttgttaga aatactttcc ctataaggaa aagaatgttc attggtacca
    15901 aatactgatt ttgagcttaa atcataatta tcatcatttt ctgtaattga atttttattg
    15961 taaaatcctt tttctttatc agaattattt tctttattac catctttagg tatatcatga
    16021 ggatttttat tttcattgct atcagtactt gattctacat catctttagg agtatttggt
    16081 tgtttctcat cagaattatc attttcatta ttattatttt cattattatt attttcatta
    16141 ttattgtttt gattgttatt actatcatta ttttcatttc cattattccc atcttgattg
    16201 ttatcatcct catctctatc cgggtcgtct ctacctcctc ctccacggtc accatcaata
    16261 tcatcatttt cccgttcatc atctggtgtc tcttggttgt ctccgcctcc cattataaat
    16321 cctggtttaa aaactatatt tgaataccct tcttttaatc ctcctacaac ttttactcta
    16381 aaacaacgca acttaaaatc ttcaaaaaaa agtatagctt gatctctaat atcctcctgt
    16441 tcttcagata tccaattgat tccatcgctt gaatattcaa caaaaacctt acttgcacta
    16501 tacggcatat cataaaataa aacagctaca tatccatttt ttgtattttg aaattccagt
    16561 tccaaattgt ctattggttt tttctctata acagatacat tcaaaatagg aactacatca
    16621 tcatttatta taattttttc tttatttaac atttctgttt taaactttcc tgttatatta
    16681 aaattttctc ccttttccaa cttttcataa taatcagtaa aatcccattc tacatctata
    16741 tcaagtcgat taccactaga tgtttctaat accatatatt tgggaaattt tatattttct
    16801 attttatcat ctttacttac ttttatttca tcactaaata caccaattcc cctatgacaa
    16861 catttcacaa tatcatagcc agaatcttca gctatagagg gtataagctc attataatca
    16921 tcaattatat aaactttctt actttctgat ataattgatt gtgccaactt attattatct
    16981 cttagtaacc cactttcatt gttgctacta tatgctttta ttgaagtttc ttctatctca
    17041 acatcacctt tagaataaac acctatagca tgttctccat tcacttcaat atccttattt
    17101 agtattctaa tatcattttc agtataaatt cctattgcat cttttccatt tgcctttatt
    17161 ttttcaacag attcgtagga tgatttaata tgtaagtctc ctccttcttc aacgtataag
    17221 gctgtcccat cagtagcaat tatgttgttt ataccaatac ttatacttcc accattttct
    17281 atatgtatta ctccttcttt tcctccttca cctattatat tcaattcatt atcatcaata
    17341 ataaatctcc catgattttt tatcaatatt ttatatttgt tggtatctat tgtaaaatta
    17401 ctgtcataag gaatataaaa tctaaactct tcatctatta ccatatcaca agaaagagta
    17461 taaactattt cttctttatt atttttattt tcttgaaccc acctttcaaa atcttcaaga
    17521 caattttcct cttgtccaaa aactttatgt ggaaaactta taaaacacaa aactattata
    17581 ctcataaaaa taaatatctc atactttttc atcttacact cctagaaatt tttagctttg
    17641 aaacaatcct gtcgaaacat atacttcacc cactataatt tttccacaat tatcaattat
    17701 tgtcaattta tataagtatc tttattaatt gttataaata aaaagctact tactaaagca
    17761 aacagacgtt tcactttaat aagtagctat atttttataa caaaatagtt ataatattag
    17821 aacttccttc atttacaatt ttttgtaaag tcttttgcat tttaactctt atctcttctg
    17881 gcatagtata taatttactt tgtaattgct cttttactaa gtcatgtagt gatttaccaa
    17941 acatatttga ttcccataaa tctgctggtt gctcttcaaa tacttccata agatatttta
    18001 tcatctcttc accttgattt tgatttccaa ctattggaga aacctctgta gatatatctg
    18061 cttttataat atgaagtgat ggtgcattgg cttttaactt gataccatat tgttttcctt
    18121 gtttcattat ttctggttct tccagactaa gttcttctaa ggaaggagct actactccat
    18181 atccttttat cttggcatct attaaagcac tttctatttt atcatactca tttttaactt
    18241 tagatagtct agttatcaga ctaagcagtt gataatctcc ttcaatttta aatccacttt
    18301 tttcttcaag gacattatag aataaatctt gctttgtctg taaatcaata tttataacac
    18361 cttctcctag ctctacatta tcaacacctg tatcttccaa aaactctaac tcagaaaatc
    18421 cttgtataat accttctata tcccttattt tacctatatc tataatactt tgttttaatg
    18481 ttgttattat gctacttttt atccaatgat ttctttcaag accttcaacc cattttggta
    18541 agttgattct tatttctgta agtggaaaat catataatac agcttccata acctcctcta
    18601 tatcttcttc ttccatttca accacattca ttggaagaac tggaacttca tacttttctt
    18661 ccaattcact tctaagcata ctcgtttcct cactttttgg acttaacgta tttaaaacca
    18721 ctgcaaatgg ttttttaaga tttttcaatt cttgtataac tctctcttct ggttctacat
    18781 agctttttct gtcaattcca gtaactgaac catctgtcaa gacaactatc cctattgtag
    18841 aatggtcttt tataactttt ttagttccta tctctgctgc cttttcaaat gtcatagctt
    18901 cttgtgacca aggagtggat actaatcttt gttttccacc ttcctcatgc cctaaagctc
    18961 cttcaactat gtatccaaca caatctacca ttcttacttt taaagatact gtgtctttta
    19021 tttttatttc tacaccatct gctggtacaa attttggttc tactgtcatt atcgttttac
    19081 ctgaaccact ttggggtatc tcatctcttg ttctatcctt tttaaattca ttgtctatat
    19141 taggtataac caacttttcc ataaattttc ttataaaagt tgattttcct gttcttacag
    19201 gtccaactac tccaatatat atatccccct gagtcctttt ggatatatct tcgtatatgt
    19261 tattattcat attattcctc ctatacatct aatcttatta aattatattt agagttaagg
    19321 gttaatattc ttaaaataga aaaataaaga ccagcaatat taatttaatt tacatataga
    19381 aatttgtaaa tttcaatgta aattaaatta atattgctgg tccaaatagt agtgtattat
    19441 attaactgac tttagtagta ttttcatttg aattattatt catctcaata agttctttac
    19501 gtctttcttt tgtcatgttc atccatataa atgtaaacac caatccaatt atggctacta
    19561 tagtaagaac tatgaagtag tacctatatc cagttacacc cggaaatgca tccaatatct
    19621 tccctgctgc taaaggacaa agtacttctg gaagatatcc taatgtagca actattccta
    19681 tagcagttcc tgatattgat aatgaataat taccttcttc aagtaacgaa tagtgtaaac
    19741 cttgaattgc atacatagat acatatattg caacacatcc aatcaatagt atataaatca
    19801 tagatgattt tgttggtgta aatattacac ctaaaagacc tgcaatcata agtataaatc
    19861 cataagatat aatctttgat gaaccaactt tatctccaag taatccagaa gcagctgatg
    19921 ctactggtct acaatactga gctaatattg agattgcaga tgcaaacacc acagtagctc
    19981 caaatgcttc agttgaataa ggcgtaaaat aataaaatga catattagct gaatatgaac
    20041 aaaacattat tattgttatt atccatgtat gaggcatttt tattactgca aaaaaggctt
    20101 ctttatcaaa ttttgctgat acctcttttt cattatcctt taatttgaaa aatactaata
    20161 ctccaactat tacatttatt gccgagtata atactataat agctgtaaga ccagatttat
    20221 cacttacttt tgatgaaata tacccaaata gtatcaatac tagagataga tgaattgcat
    20281 tggtaattcc acgaccactt tccataaatc caaaagcttt tccttgttca ttttcagatg
    20341 ctaacattct aacagctttt acaagagctg gccaaaaagt aagtattgtt gttattcccc
    20401 ataaggcatg gattaaaaac acaacaatat atggaggata aagtgttaat acaagaccag
    20461 atattcctgt aataattaaa gaacctgaaa gcaattttct ggctgaaata cggtctgcta
    20521 aaaaaccacc aaaaaggtat gataccattg caagtagacc ataaatactt cctaagcttc
    20581 ccatttgtgt atttgtaaga ttaaatgctt gtgcaaaagt atcataataa taattcttta
    20641 aatatggtaa agcatatata aatgctcctg ctacaaagag tattatcaag actttgaaat
    20701 ttttccaaat gcttggttta tttacttcaa ctgacatact tcctccttat gtaaatacct
    20761 gtaaattttc atgataatta attattgctt attgtattgt ttattcaata tttcggaata
    20821 tttattaata tattaggtta atctatcaat aatttatggt gagttatgag ctaaaagtaa
    20881 actcttttag ctcaccataa taattatatt tttatttata ctaacgtcca gagttattag
    20941 atatcttttt ttcatagttc ttccatagca ttaaacctgt tattataaca aaaagacctc
    21001 ctcctatcat ttcaatctca tagattatat tatcttttaa agtctccata actggtgccg
    21061 ttgagaaaag tatgccaact acagttacta caagtaccat tctggcaata ttgatacaaa
    21121 ctgaatcact ttttgcaatt gaatatggtc tttcttcatt tggtcttgtc tttctaagtc
    21181 taatataaga tgtaaaaagc aagacatatg gaaataatgc tgttaatgct gtcatagtaa
    21241 caagaacatt gtatatatta tctactgatg gtaataagtt tgttcctaca agaagtagac
    21301 tcactattat agcctgaact attactgcat ttgatggtat attgtattta tttgtaacag
    21361 tcaattgctt aggaaataca ccttctctta catttccaaa aagcatcttt actggacctg
    21421 ctatataaag tattaatgct cctagtactg ataaagttat tccaaatgct actattctta
    21481 taaaccaact tcctatacct aaatcttgtg caactttagc taatgcatct agtatccctg
    21541 tagatgctgc aattttatct ggaggaagta tcattgttat tgctactgaa cctaagatat
    21601 agattcctcc tattaaaaca gccacagtta atatagcttt aggaaagttt ttcttagcat
    21661 tatccatttc ggttatgaaa ttagcagtcg tttcagctcc tgataatgca aatattatag
    21721 cagatataga aactaatgaa ttggcatcta tttttggtat tatattttgg attgtatata
    21781 tcgatgctga tggagctttt ttgagaataa ctacagacat aaatgccatc actataagta
    21841 atatagcagg aattgtagaa cctaatgctc ctgtattcgt aaaaaatttt ccaaatgcca
    21901 tcccacgagt acttactaag gacaacagcc aaaatattat gagtgaaagt gctaaaataa
    21961 acatcttatt gtttgataaa tctggatttc caagcatata tgcaatattt atcgctaaaa
    22021 aagtcaagaa agaagaatac caaaatatct ttgatgtcca atttagccat gacaccataa
    22081 atccccactt ctctccataa gcttgtttaa cccattctcc aagtccacca tcttttggat
    22141 atgttgcagc caactctgca catataagtg atgcaggaac aaagaatata aaagcaaaca
    22201 ataaccaaac tggtatagaa ccaagaccca atccaaaact agaggcagta gatttagcta
    22261 tccatctaat cccaaatagt gctgatatat tcataaatac taaatcccaa aatccaattt
    22321 tctttttcac tgtaattcct ccaatttcaa atttattcag actcatacac aatgtattga
    22381 cttaaatatc aagtataagt tcttcaacac ttcttggata attagttata attgtagcac
    22441 cattcttacc tactattgct gtatctgagt gtctaaatcc tccaactcca ggtatatata
    22501 tccctggctc catagaaaat accattcctt cttctaatat taattcattg tcaaatctta
    22561 aatatggctc ttcatgttct gataaaccta aaccatgacc aattctatga tttgaatata
    22621 actctagacc atactttgca acaacagctc ttgctgcttc atccaccatt cttgctggta
    22681 taccagcttt tattgtatct aatccagctt gttgagcctc tactgcaatc ttaaacactt
    22741 ctttttgtct ttctgttggt ttgcctataa taaaagttct ttcattttct gctctatagt
    22801 tttcatacca aacctgtcta ctatgtatta ctatatctcc tctttgaagt attctagtat
    22861 tggaatctaa atgaggttgt gctgttctat caatccctga acaagtccag tttgcaaatc
    22921 ctatatatgt atcaggataa ttttcagaaa catattttag taaagcatta tcccctgcaa
    22981 cgtcaaactc caattcactc atcccaactc taacattttc taaagaccct tttattccta
    23041 tatcagatag gtaacctgct atcttcaaaa attctatttc ttttgcatct tttacatatc
    23101 tcatttcaaa tattttactt ccaacatctt tgatagcaaa tgacttatca gttatatact
    23161 ctgaaaagct tgcagatact atatcttttt ctattccaac agttgttcct ttagggtatt
    23221 tatttaaaat tatatctaag taatgtttat gtgatattcc atgttctttc atttctggta
    23281 tttcataata cacatataca ttatcaactt ttgcaacttc tttagcatgt aattcttcta
    23341 atccaggtac tattaattct attttatctt gagttactac tgttacaatt ggtctagaat
    23401 aagttattgc tttaaatcca ctaatataaa attgattgtc tggttcaaat attaaagcaa
    23461 tttcaatgct tttttcattc atgtactttc tcaatctttc tagtctcata ttatttgaca
    23521 taatgcacct ctttcttaat attcagataa tttattcaat acaacaagga tgaatatatt
    23581 attttaaaat tcttaatatt tttagtactt gtcgtatttg tatgtaaatt aattttattt
    23641 gtgattattt tatcataatc atgattattt tgtcaatcat gattttattt taaaaaattt
    23701 tttatattct agtgatttta aattatctaa aatataacga gtatacattg tattttgtaa
    23761 tattattctt gatttatggt aagtttaatg ataaaatcac gattatataa actatattga
    23821 ttatttgtag gtgaataaaa tgacaaataa agaattacaa aagaaaagga tattgatgta
    23881 tttcatagaa gctgctcaaa atattatgga aaacgaaggt atagaaaata ttacacttcg
    23941 taaggttgca gatatggctg gctataatag ttcaactcta tataaatact ttaaaaattt
    24001 agaccattta atatcatttg catctataaa atattttaaa gattataact tgaatatttc
    24061 aagatgtata gaaaatgtca atgatgaata taagaaatat ataattatgt ggaaattatt
    24121 ttgtaagcat tcttttgata atgctcaagc tttttaccag gtatttttta acttgtctag
    24181 tgatgaactt agctatataa caaaacaata ttatgatatg tttccagaag atttaggtat
    24241 tcatgatagt gacatatctt taatgattac aggagaaagt ataaaggaaa gaaataagat
    24301 actattaaac aaccttgtag atactggata tataccagct aaagatttag acataatcaa
    24361 tgatataatt atttcttttt atcaaaatct attattctta aaaaagaaca caggaaaaaa
    24421 ttctgatgat gatgaattaa ctatgaaaat gatttcttct attgaataca taataaaaca
    24481 tgctaaataa aattaaaata tggctgtctc aaaatagaga taagcctttt ttattgttga
    24541 aataataaaa atatatttaa tttcatataa aaaagagtgc ctcgtaaact aaaaagttca
    24601 ttttgagaca cccctaaaat aaatttatta tttattatac aatagtttat atatcatcac
    24661 ctaaaactac ttcttccatt tcatgctttt tacttctcat cattagttct attccaactt
    24721 ctttaggatt tgaacctttc tttattacag aatatatagc attagttata ggcatatcta
    24781 tatctaattt ttcagaaaca tcatgtgcta cttcagtagc agttatgcct tctacaacca
    24841 tctttacttc ttttaaagta tcttctaaac tcataccttt acctatgagt ataccagctc
    24901 ttctatttct actatgcata cttgtacaag taactattaa atctccaata cctgaaagac
    24961 ctgcaaaggt agacatatta gctcccatag caattccaag tctgctcatt tcactaatac
    25021 ctcttgtcat aagggcagct tttgcattat caccataccc taatccgtca catatcccag
    25081 ctccaaatgc tataatattt tttaatgctc ctccaagttc tactccaact atgtctggat
    25141 tcgtataaac tctaagttta gggctcataa ataaatcttg tatcatctgt gctattttta
    25201 aatctttaga agcaactact acggtagtag gaatatccct tgctacttct tcagcatgag
    25261 atggcccaga tagtattaca tatggatttt gtggtaattc ttcttcacag acttgagata
    25321 atctaagccc agtccctttt tcaagacctt tagctacatt aacaataact tgtccttctt
    25381 ttataaatgg ttttattttt tggcaagtac ttcttacagc ctgtgatgga actgctaaaa
    25441 ctatcacctt acaatctttt atagtttttt ctatatcagt acttatagtt atattatttg
    25501 gaaataatac tcctggtaaa tagtctgtat tttctttagt tctgtttatt tttttagctt
    25561 gttcctcttt tcgagtccac atgctcacat cattaccttt ttttgcaagc cctaaagcta
    25621 atgcacttcc ccagcttcca gtacctaata cacatacttt ctccatgttt aacaccacct
    25681 gagtataata tatttactat tctttctttt gaccaatttt tctctctgtc ccatttaata
    25741 atcgctttat atttgctctg tgattatata ttactgatgc agttaagaac agagctacta
    25801 ttaaaccagc tttatttttt accataatca taaatattgg tgaacatcct attcctacaa
    25861 cagaacccaa tgaaacatac tttgttatag ctaccaccaa tataaatact gctagacaca
    25921 ttagtgttat tactggattt acagctagca ttgcccctag tgaagttgca acacctttgc
    25981 ctcctctaaa tcctaaaacc gctggccaat tatgacctgc tacaacacat ataactgcca
    26041 gatatccagc taaaagagta tctattccaa ccaatcttgc tgcaaattct gatattaaaa
    26101 cagccattac acctttaaga acatcaccta aaaatgtcat tgctcctgct ctttttccaa
    26161 gtgtcctaag tacatttgtc gaacctgcat taccagaacc ttgagtcctt atatcaaccc
    26221 cagcaattcg ctttgcaact atgtatgagg tagatatatt tcctaaaaga tatgcaacta
    26281 cagcaataat tatataacta aatatctcca ctgaatttcc cccctttagt tatattttaa
    26341 gatatttatt ttttattttt ttgtctatac tcaaacttta tggaagttcc ttcaaatcca
    26401 aaattttctc ttatcttatt ctcaaggtat ctttgatatg agaagtgagt taaatcctta
    26461 tcatttataa acaatgtaat tttaggaggt ctaatgtcag tttgagtccc atagtaaatt
    26521 tttaatcttc tacctttgtc agatggtggt tgatttaaca ttacagcttc tccaattact
    26581 tcattcagtg ctgaagttga tattctctta gaatgttcat ttgacacata ttcaactgta
    26641 tctagtatct tgttcattct ttgattagtt tttgcagaaa caaatacgat tggagcatac
    26701 atcataaatg gaaatttttc ttttatatct tttgtgtaat tactcatagt cttattatct
    26761 ttctctatta aatcccattt attgattaca aatatgcatc cttttccttc atcatgtgct
    26821 atacctgcaa cctttgtatc ttgttctgtt acaccttcta atgcatctat tactatcaat
    26881 actacatctg ctctatctac agcactcata gctcttatta cactgtattt ttctattgtc
    26941 tcatatattt tactttttct tctaagccct gctgtatcta ttagaagaaa tttctgtcca
    27001 tttttttcaa aataagtatc aattgcgtct ctagtagttc ctgcaattgg acttacaatt
    27061 actctttctt ctccaagtat cttattgagt atagaacttt ttcctgcatt tggtttacct
    27121 gttatagcta ctcttattat atcttcttca tactctgtat ctaatcctgc tggaaaattt
    27181 tcaactatct catctaataa atctccaaat cccatactat tggctcctga aactgcaaaa
    27241 ggcgttccaa atcccaactc ataaaaatcg tatatattat caaattgact ttgactatca
    27301 atcttattaa ccactaagat tactggtttt tttgtctttc taagcaattg tgcaatttct
    27361 ttatcagcag ctgttattcc agctttacca tcaactataa aaagtattac atgtgacatg
    27421 tccattgcaa gcatggcttg atttctcatt tgagataata ttatatcttc gctatcaggt
    27481 tcaattcctc ctgtatccac taatgtaaaa tatttatcta accattctac ttcagcaaat
    27541 attctatctc ttgtaactcc aggtgtattt tcaactattg atatcctttt tcctgcaaat
    27601 ttattaaata ttgtagactt accaacgttt ggtctcccaa ctacagctac aactggccta
    27661 cttatactca ttttatttct ccttccatct tttgttttct attttaaaat tttatccaca
    27721 aaatcttttc cttcattcaa acaagggata atttttattc tcataagttc ttctaattga
    27781 tttaattcaa tattatctaa gaaaatttct tcatctgctt ttagcatact tcttgttata
    27841 taaagagctt ctcctaattc tttatcttca agttgttctt ttaaatcctt agctgttaaa
    27901 agacctgata cagttattgt ctctccaaaa aacttgtttt tgatttcata tacatttact
    27961 tgaagatttt taaacttgtc catcatagca tctgccatac tctgtataaa ttcatatgca
    28021 gaatgaccag tagctattga tactttcttc tctcttttta gaatattctc aggcaatata
    28081 tttagatact cttcaatctc tgtttttaac ttacgtatca tacctacacc atcttcaaac
    28141 tgtaaaaaac cttcatattc ttcatatcca ggcaattcac tattagatag tatataaaat
    28201 tcatctgata aaaatgcaaa tcgagtacct aatttttcaa gatatttctg ttgtatttga
    28261 tgtatttgct ctatagtttt acttgcgctc ttatcattaa atatatttaa ttctactaga
    28321 ttttctctat gctttgtaat cccaactgga actatcgcaa cactgtttac atatggataa
    28381 agttgagcta gttcttttat tgttctatcc aattcctttc catcatttat acctggacat
    28441 aaaacaattt gacagttcat ttctatatga gcatctgcca atctcttcat tataccatat
    28501 aattttcctg caaatttatt gcttatcatt ttttgtctta actctggatt agttgtatgc
    28561 acagatatat ttataggact tattctatat tttataatat tatttatatc ttcttcactc
    28621 atatttgtaa gtgtgacaaa atttccttgt aaaaaagata atctcgaatc atcatcttta
    28681 aaataaagag tttctctcat accttctggc aattggtcta taaaacaaaa catacactta
    28741 tttctacagc ttttagcttg gtcaattatc ggatttgtaa attcaacacc caaatcttca
    28801 tcatagtctt tttctatctc gtatatgtag acttcgccat cttttttttg tatttctaca
    28861 tctaaatatt catcacttag taagaatcta tactctatta tatcatgtat tggctgttca
    28921 ttcacagata taagtaaatc tcctacctct atacccattt cttctgcaat actatcttta
    28981 taaaccttac ttataatatt atttactttt tttacattta cttccaatat tttcaccact
    29041 cttttgtatt catcaatgct tattataatg tattttaata tgcaatttat ttatttgtta
    29101 tattttatga tagcattttt aagcatttca tgtcataata acacatttta attctaatag
    29161 tcaatataag taaatagcta taaaatagat tagaacaaat aatattcaaa tttaagtttc
    29221 ttaaaaattt gaatattatt tgttcttaaa aaaattttat aaatttaatg ttttactatg
    29281 attaacgtcc catttgtcat atcatgaacc attccaccta cacactttga catcaacaat
    29341 gccttatttt gtaagtcttt ctcatcattt gcataaaata ttggacaacc tccaccattt
    29401 ttcatattct tatccaacgt aactatagct agtgtatatt catttaaacc tatatccatt
    29461 cccatcttat gcacttcctt tctttcctat tttataattt tttagtgata agttttttcc
    29521 tttagaactt gaaagtattg ggcatgactt tacggcttcc attacttttt ccacattctt
    29581 atctactggt aaataagcaa tcattatact ttcatcctct ttattccttc taggtaatgg
    29641 tacgaatgaa ggttctccat aatctccata taaacctaac cttgaatata tattgtatac
    29701 tattgcctgt ctttgacctg agtcaaataa tatccctgca ttagcataat ctttattttt
    29761 aggaattatt tgtattccta cacctctatt aatatatact tctctatcac tttttagacc
    29821 tatatttgtt attcccttta aatctcctac cttcaatata gactcatcta caaaactaat
    29881 ctcagcaggc attacatcag ctatgtctcc aatacttttt ctagtaagaa gtttttttaa
    29941 tataaaggct aacactaatc cacaaattga acttattacc aaactcattc cttcacttat
    30001 tttcgtttct gcaagtatta cataatacaa tcctattgtt aaaaaagatg taactataca
    30061 catataattt cttacttcat aggttctagc tatctcttct atgaatgcag ctcctctctt
    30121 tacaagttga acttcctcta agttttgcaa tgtatttctt ctatttgctc tcacttgtct
    30181 aaattgctct gctgctaggg ataaaaaagt tatagatgta taagaacgat ttataagagc
    30241 tggaaccaat aatgctccta atgaagaagc gacgaatgct aatataagtt gagatagtaa
    30301 aacatttggt tgcgttggat actgtttttg gtctaaattc aacattataa ttctagatgt
    30361 tataccaata ataacagcaa caaaaaatac tctatccatt aaatcactcc taaaatattt
    30421 aatttgaaat tttacatgta aatctacaaa gtctttctag aaaaatcact ctgctttcct
    30481 tttgatgttt ctatgatagg tgtacttttc actacatcta tcatgacatc tatatctttg
    30541 agtattggca tatatggtat aaccacagta cttttttcta aattggtctt agatatagca
    30601 acaatatcaa cctcatctac atctctatct atccccatat gaataaatag attatgtatt
    30661 atagcttgtc tttgccctat atcatttact attccaaatg cacctaaatc tcttggtata
    30721 acttctatag ccagacattc atttctatac ttttctcttg tactttctag acctatgtta
    30781 gttattatta caccatttac cattaaaata ggtccttcaa aacttatttt tgcaggaact
    30841 atatctgcta tatctgctat actgttcctt cttaaaaatc ttctaaaaat caaaccaaca
    30901 atagctcctg acacaatagc taagattgtg caataaaaaa agctaaggcc atactttctt
    30961 gcaaaaacga tataaactat cgaagatacc agtgcagaaa aaagacttat ataacttcta
    31021 gattcatacg tagatgctat ttcttcaacg taagcgtctc cttttggtac taattcttca
    31081 ttatcgatat tctttagtgt tattctttct tgttctgcaa gaccttgaaa ctgttgtatt
    31141 gctactgcaa aaaatgtcaa ggctgcaaac tccttatcta taagtgcagg taatgctata
    31201 gcacctaacg aagctgaaag cccagatata attatctgtt ctaaataatc ttgtggtctt
    31261 gatgggtatt gtttgtctgt aactcttaaa actaatcctc tacataatat tcctacaact
    31321 aatgcaacta taaaagagtg tctaaataaa tttgcattca ataaactttc ttccattttc
    31381 tcagctcctt ctcttatata gtttgtgcaa aaaacaaaaa aaattccctt ctatttaagg
    31441 aaattttttt gtaatattgt aactataaat tcgctaccaa tgccaagttc actttttact
    31501 tttatacatc catttagtga tttgactata tgctttgtta tagccaatcc taaacccgtt
    31561 cctcctacat ccctacttct tgctttatct accctataaa atcgttcaaa tatgcgttct
    31621 acatcttctt ttggtatccc tacaccattg tctataactt taattacgat tttttcttca
    31681 tcttttaaca ctacaacttg tacaatccca ttatcttggg tatactttat agcattatca
    31741 actaggttta agaacacttg ctttatatag tctttattgg atagtatact tattgattta
    31801 tcatcacatt tatataaaac ttctatattt ttttcactag ctgaatgttg agttatttca
    31861 tatacctctt taaatacatc atatactaca acattttcca taagaagagt atctttattt
    31921 tctacaaatg ataacagcaa tatatcatca atcaaccttt ttaatctatc tgattcgctt
    31981 tctattattt ctaagaatct atttctagta ttcacatcta tattttcatt tgactttagt
    32041 gtttcaacaa acccacttat agatgtaagt ggtgttttaa gttcatgact tacatttgca
    32101 acaaaatcac ttctcatatt ttcaagttta acttttttag taatatcttc tatatttact
    32161 atcgaaccta ttattacgtt gttagtattc tgaagataaa ctgggtctac ttttatctta
    32221 tatacgatat catctttagt agtaatatta gcagtttcat tatctttaga accaataaat
    32281 tgaagtattt gttttaatat ttcttcttct tttattacaa cattaatatt atgaccttca
    32341 actaattgat ttggttcact ctttatcatt tcttttgctt catcatttat cagaagtata
    32401 tttccattta catctatagc taaaattcca tgagatatac tctttaatat agaccttagc
    32461 tgtaaatgtt tatactgtac ttcttctaag gttttatcca tattctttat catatgatta
    32521 aaatttctag ctaattcgcc aagttctcct ttggctgata tgttaagcct agcatgatat
    32581 tcattattac ttactttttt tgagatgtat ataaactctt ttaaatattt ccttaatgtt
    32641 attgtgtatc ttacagctaa tataacaatg gctatggaca acataacaat aaaaaaatat
    32701 atactattta aatcttccac aagataacac tcctaaaata taaccttttt aatctatttt
    32761 gtatcctaca cctcttatag tctctatata tttttccgat ttatcttcat cttctatttt
    32821 ttttcttaaa tatcttatat gaacatctac tgttctagtt tctccatagt attcataccc
    32881 ccatatttta tccaaaagat aatttcttga aagtactttt cctttatttt gaattaataa
    32941 ttttaacaat tcaaattcct taagagttaa ctctatcttt tcagagcctt tggtaacttc
    33001 atgttttgat aaatctagtt ttaaattacc tgtagtaagt atattgtttt cttcacctaa
    33061 gctagtcaaa ttatatctcc ttaaaacaga actaatccta gctaacaact cttttatact
    33121 aaatggctta gttatatagt catcagcacc tatttcaagc ccttcaacct tgtcattttc
    33181 catattttta gcagtaagca ttataacagg aatatttttt aagtccttat cacttcttat
    33241 ttttctcaaa acttctattc cacttatatt tggtaacatc caatctaaaa gtattaaatc
    33301 tggtttaatt tccttagcct ttataaatcc gtcaaatcca tcatatgaat aactaacttc
    33361 gtaatttgac acctccaaat tgaattttaa tagctcaact atatgcattt catcgtctat
    33421 aacaagcact ttagtattca ttaaaaagct cctctctatt ttatctgtag taccgttcct
    33481 attcgttctg atgccttatt atgttttcta taagagtgga atttatctgc tctacaacta
    33541 gtgcataaat ttaaatttat tatattttct tttttaactc cactacatct aagcatatac
    33601 tcattaattt tccataaatc taaatagtaa cttccctctt ttattatata gaacttttca
    33661 tcattatttg taagaattgt gttaaatttt tctactaaat cttcagacac ttcataacaa
    33721 catggtccaa ttgatggtcc aattatacat actaaatctt caggaactgt tttatagcat
    33781 tcagacatta attttattgt tttatgacct atattactaa aagtccctct ccaacctgca
    33841 tgagccagtc ctatggcttt atttttagca tctataattg atataggtac acagtctgct
    33901 gtaaacagta aaagtggtac tttttccaag tttgttataa gtgcatctcc atctcttctt
    33961 ttccctatag tatctttatt gactatatta actatatctg aatgtatttg agaattacta
    34021 gttagatttt caaatgtcaa atcacattct ttacatactt ttaacatatc ttctctattt
    34081 tttgcatcta tattcttaca tgttataact agatttacag aatttaattt ttcatcaagt
    34141 tcttcacaat taccacttaa attaacatac tctttaatat cttgtacatt ttttatattt
    34201 atataatctt tcatcatttg tctccttttt ctatcagtat acttttaagt tcatttacaa
    34261 aagtatttat atctttaaat tgtctataca cagaagcaaa tcttacatag gcaacctcat
    34321 ctaactcttt caatttatcc attaccatct caccgatttt tttggtttca atttcttcta
    34381 taaaacattt atttatttca ttttcaatat gtacaacaat actttcaatc tcgtcaatag
    34441 aaacaggtct tttttcacat gcttttaaca atccatattt tatcttttct ctatcaaaat
    34501 attctctact attatccttt ttaatgacca ttaaaggagt tgtttctatt ttctcatacg
    34561 tagtaaatct ctttttacat gattcacact cacgtcttct tctgatagat tttaaatctg
    34621 tatgtctaga atctattacc tttgattctt tataattaca ataaggacat tgcatctata
    34681 ttcctccttt gtttaactat atctcaaact catctaagct taattctgaa cctatattta
    34741 ctattattgt atcacaacct attttaagta tatcattcca aaatataact tcttcatccc
    34801 ctcctcttga aaaaaaactt ctacttccat ctccaaaaat ggtaaatgag actaccttac
    34861 cttcgtgaat atccatgtct atgtctatta taaaccccat cctttttcca ttttttacat
    34921 ttataatttc tttttccatt atatcagaaa ctctaatcat attgtactca ccctttcttt
    34981 aaaaataaat atgtatcgaa gtaaaaaaaa atgacctata taggtcattt aaattaaaat
    35041 aatgtttaca gtccatggat tacttataca tattttctca tattctttaa agcatttttt
    35101 tcaattcttg atacttgtgc ttgagatata ccgatttcat cagcaacttc tatctgagtt
    35161 cttcctttgt aaaaccttaa atctaatacc aacttttctc tactatttaa tttcttaata
    35221 gcttctttaa gtgatatttc ttgcaaccaa ttttcatcag tatctttttt atcttgaacc
    35281 tgatccataa cgaatattgc atctccattg tcttgatata ctgggtcaaa cagagatatt
    35341 gggtcttgta tggcatcaag tgccattaca actgattcta cttctaattc taattccttt
    35401 gctatttctg atactgtagg ttctttagaa tttgttctaa ttaatctttc tctaacttgt
    35461 agtgccttat atgctatatc ttttaatgac ctacttactc taattgggtt attgtctctt
    35521 agataccttc taatttctcc tataatcata ggaacagcat aagttgaaaa ccttacattt
    35581 tggcttaaat caaagttatc tatagctttt ataagaccaa tacaacctat ttgaaataaa
    35641 tcgtctatat tttctcctct gttgttaaac ttttttatta cactcaagac taatcttaaa
    35701 ttccctctta caaactgttg tctggcttct tcatcaccat tttttatttg taataaaagt
    35761 tccttcattt gcttattttt aagaactgga agttctgatg tattaacacc acatatttca
    35821 accttattaa cttgcatata ttttcagtcc tctctcaaaa gtattcatct attgaaatta
    35881 tttacatttc caattttttt atacttttta agaagaatta atttatcatt atacaaattt
    35941 tttcatttct ttttgcaacc ttgagattat tttcttttca agtctagata tgtaggactg
    36001 tgatattcca agcattccag caacttcttt ttgtgttttt tcaatacctt tatcaataag
    36061 accaaatctt aattccataa tttgcttttc tctgtcactt aatctgtcaa gtgccataac
    36121 caacaaatct ctatctattt cttcttcaat tattttgtat atttcatcat tttctgtacc
    36181 caatacatca gataataaaa gttcgtttcc atctaaatct atatttaaag gttcatcaaa
    36241 tgatacttct gttttctttt tattattttt tcttaagtac attaatattt cattttctat
    36301 acatctcgaa gcataagttg ccaattttat atttttattc agtttaaaag tattaactgc
    36361 ttttatcaaa cctatagttc ctattgaaat caaatcttct acatctatac ctgtattttc
    36421 aaattttctc gatatgtaga ctactaatct aagatttctt tctattaaaa ttgactttac
    36481 actttcatcc gtttctagct tttgtaaaag ctccatttct tcttctggtt tcaatggagg
    36541 aggaagtata tttgcccctc ccatatagta tattcccttt ggctttatta tttttaattt
    36601 aatacctaac atagtaataa agcttattat tctttctttc aatcgtaaca ttccttgtcc
    36661 cccttaaatt ttcacctaaa atccaggcaa tatatttgga ttcattattg ctccatattc
    36721 tctatcatta aaatttgaaa taccaagtat tatatttcct atcttttgct catctacttc
    36781 tatatagtca gcttttaagc ctattattat gcttgtctta ttacttccag catgtttata
    36841 aggtattatt ctaactctac ctgaagtttt atcatctaaa cttcctataa tttcttgtgc
    36901 tttcttcata tctatatctt cataattaat atttaatagt ttttctggaa taaatccttc
    36961 taacacacta gacttaacta ttattacatc actttgactt attgggtctt ttaacaaatt
    37021 accactatct actaaagcct tacagcaaaa acttttttct agtaagttta tatttatagt
    37081 ctttgtaagc tccttaatgt acttaagcat tttcaaatct ttataaatgt attttaataa
    37141 ttcacaactc acataagtac atgcaattaa gaaagatatt tttaagtgac ttattcctgt
    37201 aaaataaatt ataaaataag tgcttccaga aataaaaatg tttactagat aaaaaactaa
    37261 cgctacatga acataatctt ttttgctctt acttctaaat gaaattaaag ttattatact
    37321 catgattatt attttaaatg gtacagtaaa tagtatattc attgatggat acaaataagc
    37381 aacagaatag gcacctccta aactagcccc caataactta ttttttttag gattatatct
    37441 tttagtaaga atagaagtac aacttataat aatataattt attactaggt tttctataac
    37501 atagtactca atatacacca tgtatccccc cttaaaacct ttaaacatat tataagatag
    37561 tatgtacaaa attttatgtc acttttgatg gtcgaatcca aaacaaattc tatttaaaaa
    37621 gaacaatgat atatgtctta tactttatgt cgtcaaaaga tattttttta ataccaaaca
    37681 aatagacttt tttgtagaat ccaatatatc taggtagaag ttattcgctc tacttttggt
    37741 atatttacaa aaaaagacta cataatttaa taatatatca agtaaatctt ttacttatat
    37801 aaaatcaaat tatatagtct gtaaattcaa atataaatta ttgtgctagt aatccatttg
    37861 catattttgc agattcattt agtgcttgtt ctggagttat gtctccagct atcatcattt
    37921 gaagttgttt ccataaatat tcatatatct ctactccatg aggtccaact gtcaatggtc
    37981 tatacatatg tttatctctt gtcaccattt cttcaaatct tgggtctcct tggtattttt
    38041 cacctttagc aactggagct ctaggtattt ctttgtggaa agcttccatt gattctttgc
    38101 ttagcatata ctcaagaagt ttaaatccaa gttctttatt tttacatgct gacattaatg
    38161 ttaaatcatc tactgaagca aaacttccaa ctgtcttatc ttctaatgat gttacatatc
    38221 cccagtttaa atccgggaat gatttatcaa aagtacttgt agcagcagag gatagcatta
    38281 tagtaaatgc agcttttcct ggtccaaata cactttcaat catttcatta ctatcttttg
    38341 ataaagcatc ttctggaata tactttttca tatcatttat aaagtttgca gctttcaagc
    38401 cttctgcatt attaaattta actgatttta aatcatcatt atatatatct ccaccagctt
    38461 gccataaata cggataccag ttccagttta agcttccaaa tactttagaa ccccaacctt
    38521 gtgcaagacc ccactggtcg atttttccat ctccatcagt atcttttgtt gctttttcac
    38581 agattctttt aaaatcatcc catgtttttg gaggtttttc tcctaatttt tctagtatat
    38641 ctttattgta gtacaatacg cctggattag cagcttctat aggtaaacca taaataccac
    38701 ccatcatttt tgcatcatct aagtatagat aattatctga agttcctgat ttttctaaat
    38761 aaggtgttaa atcttctacc gcacccattt ctataaattg aggaaacatc tctgcataca
    38821 tgtatcctat atctggacct tcacctgcac ttattgctgt tgcatatttt tctgcgtagt
    38881 tatcccatgg tactatctga aattcaattt cacagttatt ttctttttca aatttttcaa
    38941 atatcggctt ccatgcatct gcatcatggt ctgttaatgg tgcagaccat acaactaatt
    39001 tttctttacc ctctttgcct ttagaatctt ctttttttga acatcctgca agaattgata
    39061 ctgatagaat ccctaccata actaaagaaa gaaccttttt tagtttaatc atgcttaatc
    39121 ccctttcaga ctttaatttg tctttttcct caaatgttta catttaattc agatttaata
    39181 ttaacaaata agattactct tgtctaatca taaaaaacta tactaactcc tataactata
    39241 ttttttttct atacctatta gatttaattc atactaaaaa cttacttttt aaattttatc
    39301 aatatttaaa aatattttta agtctagcca caaactaact atctaaattg aacaaaataa
    39361 aaagaagtct attgacttct ttataagctt acatattatc ttcttcttct taggaatgta
    39421 ggtatctcca tgctctcatc atcatcttct tcaattatac ttgccttttt aggaggctct
    39481 attttttcct cagcaattac ttcttcttca atttctttta cagcttgttt tactgttgta
    39541 tttaatgaag aacgtatgct tgatttaggt ttagtatcta aatctaaggc accattttgt
    39601 aatccttcaa atcctgtcgc gattactgta atcattattt catcacctaa atcttctttt
    39661 atagaagctc caaatataac atttgcttct gggtcacagg attccataac taaagttgat
    39721 gcctcattaa cttcaaataa tcctaagtta ggaccacctg taacattaag aagtactcct
    39781 ttagctcctt gtattgatgt ttctagaagt ggagattgaa tagcttgtct tgcagcatca
    39841 attgctctag tttcaccact agcactacct atacccatat gagcaagtcc cttgtctttc
    39901 attatagtag taacatctgc aaagtccaag tttattaacc cttcaactgc tataaggtct
    39961 gaaattgatt gtataccttg ttttaataca tcatctgcaa ctgcaaaagc atctaacatt
    40021 gatgtatttt tttgtactat ctgtaaaagt ctatcatttg gtatcgttat aagagtatct
    40081 acttttgatt taagttctgc tattccacct tcagcgttct tcattcttat cttaccttca
    40141 aatgcaaaag gtttggtaac tacacctact gtaagtatcc ccatttcttt tgccaagcct
    40201 gcaaccactg gagcagctcc tgtaccagta ccaccgccca ttccggctgt tacaaagacc
    40261 atatcagctc cttgaagtaa ctttactatt tcatctttac tctcctcagc agctcttttt
    40321 cctacttctg gatttgctcc tgctccaagt cctctagtta gtttttctcc tatttgaact
    40381 ttatattcag cttttgatgt atataaagct tgtttatctg tatttactga tataaattca
    40441 acgcctttta gttgagcttc taccattcta ttgacagcat tgtttccacc gccacctaca
    40501 cctattactt taatttgtgc acattcttct aattctacgt caaagtttag catcataaac
    40561 ccccttctct catgattcaa agttatcgta tgtattaatt atatcatttt cttcttttat
    40621 tttgttaacc tttaagtaac atattccaca aaaacgtaaa ttttcctttt taaatttctt
    40681 acttatattg tcaaatatta ctctttaagt ataaaataat ttacgtatat attaaatgct
    40741 ctttaatttt tacgtttttt attcataata ttactaataa tatatcgtct aattatagat
    40801 aagttattaa acaatctcat accaaaaact aatacagcaa catagtaaag agaaactcct
    40861 aacttttctc ctatataagt caataatata gccaatatag cattacctat gaaaccagta
    40921 ataaaaatta cattatcata gttatcttca aaattggatt ttatcgctcc aaaaatagaa
    40981 tccattattg caagaatagc tactgacata tatatggaat aatccataga atatgtaaat
    41041 ggaatatagt aacctactac tacaccaaat gctaatcctc ctaaaaccca taacataaat
    41101 cttcacctct ttattttact ttgaaacaca actacattac aatccttttt attaattttt
    41161 tttacttttt ctttattttt ttgtattttt cgttttattt tgcaaataaa ttcactttat
    41221 ttccattatt ttcctgaact tttatattaa ttccatatat atccttaaga gatttagcat
    41281 atgattctgg agagtttata gctgcactca ataaatctat atctcctata gcttttatta
    41341 taaatggttg tccatatgta gtatcattta ctgtaatagt agctcctgaa cattttatct
    41401 tacttgttgc tagtactctt tctccattta tagaaattgc tcttgctcca gcctttttta
    41461 aatcatttaa aactctcaaa atatctatat catgtataat caaatcgttt ggattctgtc
    41521 cgtcttttaa ttctctctca ctatccctca tagtaatagt tatgcctggc cctgtaatag
    41581 ttgaataacc acttaattct ttaacttctt caagctcttt ttgcataagt gtttggatag
    41641 attcatttcc attctttttt gcttctttat attcattcaa agtttttttg ttctttttaa
    41701 gagtttcttt taagtttttt atttcttttt ttgtattttc tacctcactt tcaatacttt
    41761 cagtttgacc taatgttatg tatactctat ttgggtctag tgattttata taagttgata
    41821 tgaaaacacc taatatgaat gctcctaata taactatttt ctttttcata ctattatttc
    41881 ccctctgctt tgtttatatc actatgacca tttatttcta tattgtcttc tttggtcact
    41941 tttactttgg cattataata tgtttctatt tcccagacaa taccatactt tatattaagt
    42001 gccgaagcca atgtatcaga atcaccaatt gcttttatta taattggttc ttttatgaca
    42061 gtgtcattca tataaagctt gtcttctttt aaatacatat atgtattaga aactattctc
    42121 tggtcgttta tagatatggc acttgcttgt gctgaattta acttatttat cattgacaat
    42181 aataaatcat aattatatag tatactatca tttttatcag agtttcctaa gtcttttgta
    42241 gaatttatct caatttttat gcctgttcct tcaacatctg tatatccagc taatgtttca
    42301 tatttttcta tttctgactt aagtatgtct tgttctcctt cattattttt gcctctataa
    42361 gtctctatat ctttcttcac actattaact tctgattgta gattctcttt ttcttttttt
    42421 aaagatttaa gttcttctgt aagttgctct cctcttttaa aagttgtcat ccctctattt
    42481 tctatattaa taattttaag ttgtaaacta acaagaacac ccaatacaat acttcctatg
    42541 attatacttt tatttataaa tctttttttc aatatatcac ttccttacaa ttgtctatcc
    42601 ttctggacta tacactgcca actttccata gttaagattt atagtccctc cattagtatt
    42661 tttattttgc aggtcaatca gaattttact taccctagat atattataat ctaagttatc
    42721 atcattagaa agtaagattt ttatattact tcttgtaagc atttctatat tgctttcttt
    42781 ttttaagttt acataattta tttttctata aattccttct tcttttaaat aatttaaagt
    42841 tttaaataca ttctccttag ttttataatt tttaaatttt atagatttat tatcatcaat
    42901 gctataatct acatctacta tcaagtcttt tttactttca ttagaacctc ttagttcttc
    42961 caataaattt ccttttttat ctatataaca ataattatct tcatctttta atactgcaaa
    43021 tatttctttt tcttttaagc ttataattat cttattggga agttttcttt ttatttccac
    43081 attttctata tatggatttt ttataagttt atttttcata tctttaaaat tgtatgcaaa
    43141 aatattttca tttagattta catttagttc tttcattata tttgatttgg tcaccctctt
    43201 atttccaatt acatctattt tctttacatc aaataaatca ctttttacaa ttatacatat
    43261 acaaaaagat aacataagta taaaaactaa aactatcatg acattattcg tatttaactt
    43321 tcttcttttt ttcaaatata atcaacccct ttggttaata aatacacctt tagagcttgt
    43381 ttttcctaca aaaaaattat aatatttaaa gtcaaatttt tgcattttat tacataacat
    43441 ccaaataagg tattaaattt tataaataaa tcaatatttc atcaaaataa acatagcata
    43501 ctacatacta tttatatatt taaatctgta tacatacaaa taaaccccta atttataata
    43561 atttagaaaa tctaatatat tataaattag gggtaaatat ttacttatct tttctttatt
    43621 cctattacct tagcttgacc ttctatactt ggagtcgttt ctttttttat ttcttttact
    43681 tccttaataa ctttttcttt ttttgttttt ttagaagttg acttttgtgt tgaattgtat
    43741 actttcatta tctcatcata tataaggtct atggcttcag gcttacctat agttttactt
    43801 gcatttgcca tatcaaccaa aagttctcta tctcctaaaa gtttaaatac tgctgtattt
    43861 aggctctctg gagttagatt tttttctaaa atagcaattc ctgccccttg tttttctata
    43921 ctcttggcat tatactcttg atgattttca gcagtataag ctttaggtat tattatagat
    43981 ggctttccaa gagccgttat ctcagctaat gaaattgctc ctgcgctacc tataaccaaa
    44041 tcacttgctg caagtgcatt tgccatatct tctaagtaag gcacaacttt ttggtatggt
    44101 ttaagattta tatcgctaat acttcccata aattcatcat aatagctttt gcctgtagca
    44161 aatataaaag ctatatcttc atttaccata ttctttatta caagtctcat tgcatcattt
    44221 atttttcttg aacctccact accaccatag caaagtacca ttcttttttc gtcacttatt
    44281 gatagattct ttcttgcaat attttttctt gataataaaa tttcttttct aactggattt
    44341 cctgtaaaaa ctaatttatc ttctgctgcc tctggaaatc ttttatgcga atcttcaaaa
    44401 cttgtaagta cctttgtaac tgttttagat aaaatcttat tagttacacc aggaaaagaa
    44461 ttttgctcat gtattatggc tggtattttc cccatagatg cattaaataa aacaggtcca
    44521 ctaacatatc caccagttcc tataactata tctggtttaa atttcttaac aatctttctt
    44581 gattgctcca aacctttaaa aagcttaaaa actcttttta cattatcgaa atctattttt
    44641 cgcttaaaac cttgaactgt tacagtcttt aattcaaatc catacttagg aactatttct
    44701 gactctattc ccttttccgt cccaacaaaa attatctcag cgtctggatg ctcatctctt
    44761 attttgtttg caatagctat agctggatac acgtgccctc cagttccacc gcctgataat
    44821 aaaactttca tcaaatcatc atctcctgtt aattaatttt gacatgcttt gagatgttta
    44881 acactattcc tacagctccc ataaagatgg tgagtgaagt tcctccataa cttataaatg
    44941 gtagtgctac acctgtagct ggcattgatg atgtcgcaac tgctatattt aaagctgctt
    45001 gtattccaat ttgtgcacct atacctataa caaccataca agcaaataca ttagaagtct
    45061 tcaaagctat tcttacacat ctgtagacta aaactacaaa tagcataata actattatac
    45121 aaccaatcaa tcctaactct tctcctatta tagcaaatat aaagtcattt tgtggctctg
    45181 gtatataaaa atacttttgt ttactctttc ctaagcctag accaaacaat ccacctgaac
    45241 ctagtgcata tagaccttgt attacctgat accccttacc aagagggtct tgaaaagggt
    45301 ctaaaaatga tgtaacacga ctaagtctat agggttcagc aattactaat gcagcaaata
    45361 aagcagcccc actccctatc atagcaaata caattttcat atccattcca gcaacaaata
    45421 tcattacaaa agtaactaga attacagtac ctgctgttga caaatttggc tgaagtatta
    45481 tcaacgcaaa aaatatccct ggaactacga gaagtggtac aacacctttt gtcaaagatt
    45541 ttattttatc ataatttttt tcaattaatt ttgcagttaa tattattgta gcaaactttg
    45601 cgatttctgc aggttgaaat gttaaagctc ctattcccaa ccatcttttt gctccgtttg
    45661 cttctatccc taaaggggtc aaaactaaca ataataatac tactgctata gctccaattg
    45721 ctgtagcatt tttcttccaa aaactataat ctattcttga tgtaataatc ataactataa
    45781 atccaagtac agcatatatt acattctttt ttagaaaata gtacgcatca ttgtgtttaa
    45841 atgaagattg tataaaactt gcactaaaca ccataactat tcctacaaat actaaaagca
    45901 tagtagtgta aaacactact ccatcaaatt cagtcttcat ccttatgtca atttgttttt
    45961 tcaaattttc tttaggcatc caactaatct acctccattc ttccatttaa gtaagtttag
    46021 aggtaagaga ttattttaaa ttgtttacat tatctttgaa gtcttttcct cttacttcaa
    46081 aactttcata catatcccaa cttgcacaag ctggtgaaag aagcactata tctccacttt
    46141 ttgaaatttc ataagaagtc ttaactgctt cttccatatc ttttactata tgtatgtcat
    46201 taaatccttt atttttagca caattttcta tatttgatgc agtttctcct aataagacca
    46261 atgatttaac atatgacttt gcagtttcaa gaagttcatc aaaattactt cccttatcca
    46321 tcccccctgc tataagtatt ataggtctat cataagactg tatagctttt atagtggaat
    46381 ctggattagt tccctttgaa tcatttacat atattacatt gtctaaattt cttacaaact
    46441 cttgtctgtg ttccactcct ttaaatgtca taagtacgtc ctttataact tctaaatcaa
    46501 ttttgcagac atatgctatt gctatagctg ccatacaatt ttctaagtta tgacctccag
    46561 gtaaacttac atcatcttta tttagaaatt tgattttatc atctatatct attattatgt
    46621 cattattttc taaatatact cctccattta cttttttagt tcttgaaaag taaattactt
    46681 tggcattgca tttatcagct aaagatttta ctatctcatc atcatagttt aatacacaga
    46741 aatcctcaac agtttggttc ataaatatat ttgcctttgc ttctatgtat ttttccatag
    46801 tatggtgtct atttaaatgg tcctctgtaa tatttaatat tgcgcttact ttaggtctaa
    46861 attcatctat actctcaagc tgaaaactgc ttagttcagt tactaacaca gactcttcac
    46921 ttgaagtttc tatagtatct attacaggat ttcctatatt accaactaca tatgtatctc
    46981 gttttgctct tgaaaaaatt tctcctacca aactagttgt agttgtcttt ccatttgtac
    47041 ctgtaatccc tataaaaatt ggattattcg atagtttaaa agctaattct acctcaccaa
    47101 ttatatactt gcctgaattt tttaatttca atatgaatgg taggtctagt ggtacacctg
    47161 gagacactac aaccatatct atatcatcta catcttctgg gtgatgtcct aatatgtatt
    47221 ttatgtcatt tatagatttc aattcatcaa gtatatttct caatttattt tcatctttta
    47281 tgtcatttac gattatactt gcacccaatt tatctaaatg tttaattgta gatataccag
    47341 tttttgcaag tcctactaat aaaacttttt ttccttttaa gtccattttt cattccccct
    47401 agccctaaaa tactgctatt atacttatcc aagctaaaac aactgttata atccaaaaaa
    47461 taaatacaac tcttgtttct ggccaaccac actgttcaaa gtggtggtgt attggagcca
    47521 tcttaaagaa tctctttctt gttgccttaa aatatccaac ttgaatcaaa actgatagag
    47581 cctccgcaaa ataaattcct ccaattatag gtattataag cactgagtta gttagaactg
    47641 aaaatgctac aactgcacct cctaatgcca ttgaacctgt gtcgcccata aacactctag
    47701 ccggatatga attaaatcct aagaaaccta aacatgctcc aacagttgct gctgctaaaa
    47761 ctgcgacttc tgtatttcca gcaatagaac ttgcaaatag cataaagaat acagaaacta
    47821 ttaatgttac tcctgatgct aatccatcta atccatcagt caagtttaca gcatttacta
    47881 ttgctacgat tataaacatc attattggta tatataatat tccaacattt atcacaaaat
    47941 ctgtaaatgg tatcataagt tgtgaagcac ttgatgatga tgtatactga taaaaagcaa
    48001 cataaaaaga taatgcaact tgaaggatta ttttttgata tgcttttagt ccaagtgatc
    48061 tttttagctt tatttttata aaatcatcta aaaagccaat aaaaccaaaa cctgcaatac
    48121 atataagacc tactgccata tcatgactaa cttttactct tgtaagtcca gttattagaa
    48181 ttgcaacaat cattataatt ccacccatag taggtgttcc gtttttagct agatgtgttt
    48241 ggggtccatc atctctaact gtctgaccaa atttaaattt tctaagcatt ggtataaata
    48301 ttggtcctat tataattact attaaaaacg caatcaatgc ggtgtacgta agctctgtta
    48361 ttcctaacat cataaaactc ctctcccttg tcaattaact cattagttta agcttattta
    48421 tttagatatt cgactatttt ttctaatctc atgcctcttg agccttttac taaaatagtg
    48481 tctcctgttt ttactaattc atttaacttg ttaaacacat cttctctatt ctcaaagtga
    48541 tatatattgg ctgaattgaa tcctaattgt tttgcttctt ctccaataaa cactgaattt
    48601 tcacctatag ttattataat atcagtatta ttcatagatg attttccaac taatctatga
    48661 ccatactctg aaatttcacc catttctagt atatctccaa gtatcgctac ccttctacct
    48721 ttatatcttc caagtatctt taaagcagca tccatagaat ctggactagc attatatgaa
    48781 tcattaatta ttgttaattt ttcatttttt attatgtcta atctcatttt tgtcccttta
    48841 aaatttttta aacctttttt tatataatct aaagaaatat ttagacacaa accaactaat
    48901 atagcagaca ttgcattata tatattatgt tctcctattg ttggtataaa tatttcctct
    48961 tttttcccat ttattacaca tataaatgtt aaactatcct cttccatagt ataactttca
    49021 caataaacat cattgttttt attaaagcca aatgttttta acttatatgc atgttctttt
    49081 tcttttaatg tagataaaaa cttatcatct ccatttacaa ttaaagtatt tgtttcatca
    49141 aagtttgaag taatctccat ctttgctttc aaaataccct cttgtgaacc tagtttttct
    49201 acatgtgata atcctatatt cgatatgact gcaattttag gatttactat atccactaaa
    49261 tattttattt cattgaatcc agacataccc atctctatta cagcacactc atgttcttta
    49321 tttagattaa ataaagtcaa tggaactcca aaatgattat ttaagttttt ttcatttttt
    49381 agtatattta actttgcaga tatggcagag taaatcatat ctctagtagt agtttttccc
    49441 acactacctg taacacctat aaatggaata tcaaattttt ctttatagta ttttgaaata
    49501 tctcctagag ccaaagatgt atcttttacc tctattaaat ttatatccga actttctaat
    49561 tttattccat tactttcatt ttttataaaa gttttacatc cactatcata tgcagacttc
    49621 ataaatgtat gcccatctaa attttctcca actatggcta caaatgcatt ttgggcattt
    49681 gcctccctgc tatctataac tatatcactt acacagtcat tataatctcc atatattaac
    49741 ttcccattag ttgcaagtac taactctttt attgttaagc actccattat taaactcctc
    49801 ctttaaaacc ttagctatat tctcttagca acaaaaggca atgtataccg ttatatatac
    49861 attgcctacg ataactctta actttataat tatatactat atttctgttt ttttgaagat
    49921 gtttatgggt atatgttaat tatctgttac tttttagttt tcaaaatata gggttatact
    49981 tgagtcttca ttaactttta ctccaggttt tgggaatata tcctttacct ttgtatcttc
    50041 tggaagttct atatctgcat ctaagtctgg ttttaacttc gcatcctcca atgcctttac
    50101 agcatctcct atttttagat ttcttacatc tggcacttta acttgcttct tttcatactc
    50161 agctttttct tcttctttat atactggttt aactcccaaa tattttaaag agtcattcat
    50221 tatttctttc actattggtc ctgctgtagt actaccaaat gcacttactc ctgttggttc
    50281 gtcaacaata gcaagaacta ctatttgtgg gtcatcacaa ggtgcgattc caacaaatga
    50341 acatatatac tttcctggag catacttacc atctataact ttttgagctg tacctgtttt
    50401 accaccaagt ctataacctg gtatatacgc tatctttcct ccaccttcag ttacaactga
    50461 ttctgcaatt tctaacattt ttttagatgt ttctttagat ataacacttc ttactttttt
    50521 tggttttact gtttcagtta tatttccttt attgtcagta taagatttta ccactcttgg
    50581 ttgcattaaa tctccaccat tagctattga tgatatagct gttataagtt gtattggagt
    50641 tactgatata gattgaccaa atgatattgt agccaattca actggtccta catttttttc
    50701 gttatacagt attcccttag cttctcctgg taaatctata cctgtcttat ccataagacc
    50761 aaatgattct atataatcat acatttttcc aacacctaat ctgcttccta actcaacaaa
    50821 tactgggttg caagagtttt gtactgcttg tttaaattct tgtgttccat gaggtctgta
    50881 atgtctccaa catttaatct ttcttcctcc aacagttaca ctacctgtac atgtgaattt
    50941 ttctccatct ttaattactc cttcttcaag agcactggaa gatgtaataa gcttaaatgt
    51001 agaacctggt tcatatgtat cacttactgc tggatttctc cacatttgat aatagccttt
    51061 tattttatct ttatcattat atttttcaag ttcttcttga taatatggat atattggcgt
    51121 tcttgaatca ttagggtcat aatctggttt tgatgctaaa gcaagtatat cacctgtttt
    51181 agggttcata gctattgcag taactttttt tgcattattt aactcataag ctttctgtac
    51241 tgctttttca gtatagtgtt gaattacttc atctatagac aacacaagac cattaccttg
    51301 tacaggctca taatattttt ccattccttg tggtatttct cttcctgaag catcagtact
    51361 tactataagt tttccaggct ttccttttaa ctttttatca tattgcattt ctacaccaga
    51421 tatacctgtt gcatctgaag aagtatgtcc taacacatat ggtgcaaaat tcccatatgg
    51481 gtaatatctt tgattatctt ctgccaccca tattccactt aatttagcat ctcttatttg
    51541 acttgcctta tcatcatcta tccatctttt tacttttaca agagccatat tttttttgct
    51601 tattaaagcg taaatatctt tataatcttc atccaaaatc tcagctacct tttcggctgc
    51661 ttctttttta tcttctactt ccacaggttt acaccaaaca gtatacttag ttacacttac
    51721 tgctaactct ttcatatttc tatcatatat agttcctctt ttgggttcta ttggtatatc
    51781 tcttgtttgt tgttctagtg cttttgtact caaccaattt cccttcataa gttgtagata
    51841 cccagtccta ataacaaggc aaaaaaacaa tgcacatgct agaataagaa cgagtaccag
    51901 ccttttctta cttatcctct ttacttttct caaatctatt ccccctagtt atccacatct
    51961 atatacttta tttgtccatc ttttggatag tccatattga gcaattcctt agcctttagc
    52021 tcaatttctt ttattgatgt tttttcagtt tcttttgcct ttagttcctc taatactatc
    52081 tctttttttc ttaaatcttt ttgtaaataa tagatatcgt acttcatttc cgagattttt
    52141 gaataaccac atagattcaa tattattact gaaaaagttg caatcagtaa aatgcattta
    52201 gctcctattt ttttcttatt tctcttttta taattattct tttttttatt tttatattca
    52261 tttagattat gtattttata attttttttc aaattctcac cccgatagta tatagtttaa
    52321 attttcctct atactatatt tgttattaat catatttctt cctctaaaat ttcatcgcta
    52381 aattaataca ctattacaca atctaattgt atttttttct atacacaaca aaaacctata
    52441 aattcactta tacttttata tgaatctata ggttagatat taatttctat ttatttttat
    52501 cacttctagt atttttagat aatttcttcc ataaatataa tatgtaacta actactctct
    52561 gattcctaag ttctccatta tattacttaa taccatctat atctatattt ttatatctaa
    52621 attttcatta tatatctcaa taacaaagaa catttcttat agtgttaatt gttttttaat
    52681 tgctttacca gtgcaacaaa atatataata ctttttaatt aattataata atcttatttt
    52741 atatataaga ttattcttta gccttataac tacttatatt ttttctgcta ctcttagctt
    52801 agcacttctt gaacgtggat ttacttctat ttcttcctca ctaggtaata taggttttct
    52861 agttattatt ttcacctcag attctttatc acattggcat ataggtaaat gctgtggaca
    52921 tatacaatct gatgctaaat gcttaaatgc atttttcact attctatctt ctaatgaatg
    52981 gaatgttatt atacatattc ttccaccttc attcattata gaagaagcat catttatcat
    53041 ctttgtaatt actccaagtt cattatttac ttctattcgt attgcctgaa aagttctttt
    53101 agctgggtga ggtccatcta ttctagcttt cttagggata gcttttttaa ttacatctac
    53161 taattctcct gtagtttcta ttggtttgtt tgctctttct tcaactataa atttagctat
    53221 acgcttagcc cagttatctt ctccataatc ttttattatc ttagttaatt catcttctgt
    53281 ataagtattt acaacatcat atgcagaaaa ctcacaccta acatccattc tcatatcaag
    53341 tggtgcatct tgcatataag aaaatcctct atcagcttca tcaagttgat gagatgaaac
    53401 tcctaaatca gctaatacac catcaatttt gtaaactcct attttttcta attcctcttt
    53461 tatattttca aaattactgt gaacaaactt cactctactt tcatattcac tcaatctctc
    53521 ttttgctgtg cttatagcat ttttatcttg gtcaaaccct ataaataatc ccttatctga
    53581 cagttttttt actatttctt tagaatgtcc tgctcctccc atagtacagt caacatacac
    53641 gccatctggc tttatattta aattctctat acactcattt aaaagaactg atacatgatg
    53701 aaattccata gttacctccc ttaaattcac tttttaaact attcttcact aatattattt
    53761 ttatttttct ttgataaata aacatgtgca attatgccac caataactcc aattagactt
    53821 ataacttgtg ccattctaag tggtcctaac attaaactat ctgttcttaa tccctctata
    53881 aaaaatcttc ctattgaata taaagttata taagtaacta taacttgacc ttcatatttt
    53941 ttattttttc taaatagtaa taaaactata aatattccaa aatcccatat agactcatat
    54001 aaaaaagttg gatgtacctt tactccatca accattattc cccaaggtaa attggtagca
    54061 cctccatgtg cttctccatt aataaaattt ccccatcttc caatagcttg tgctaaaggc
    54121 attccaagta taactgtatc agccattttt aagaagttaa tatttttaat cttagtgtat
    54181 atataaccag ctaatattcc accaattaac cctccatgta tagcaagtcc accacctcta
    54241 aaattaaaaa tttgagacat attttgagca tagtaactcc aattaaatac aacataatag
    54301 attcttgcac agattagtcc aactggaatt gctattatag ctatatttaa tacatcatct
    54361 tctttaattc ccactctttt tgcttctttt attgctatta aagttcctaa aatcattcca
    54421 catgccataa gtattccata ccacatgatg tctatgccaa acagtgtaaa tgctactcta
    54481 tccataacgt cacctctttg tattaattga aaatatttcc aaagcaatat gctataatta
    54541 caattaattg taattatact aaattatgat aacacattaa tgttaattct acaaaaaata
    54601 ttaaaattta ttctacaact ccctacacta tattatatct aattactata aaatttttta
    54661 aactgaatct ctcatgacta aagttacaag tgtacataga tattttttaa tcaaaaagat
    54721 tgatgcatat atacatcaac ctcttctaat tcttatctat agctcttaaa tttttacctc
    54781 aatttatata aatatatttt ataaatttgt tttaccaaaa taaacattta aaaacataaa
    54841 ctaatactta attagttatt cttattatga ttaagtttct atttaggctc tacaatagaa
    54901 ataacacaat actcttcttt aaaatgctct tttaatcttt cttcaacttc ctcaaaagta
    54961 atatctttaa taacatctaa atactccaat agatttatat ccttaaaaac ataagatata
    55021 aaactattac ctataaagtt tatagaatca aagcacttaa taaatgaccc tatttttttc
    55081 tttttagttc tctcaaactc ttcttttgat aatccttctt tttttgattt ttctatataa
    55141 tcaagaatta tttcttttac ttttttaggc tctttagaat ctccagctat tatgctaaaa
    55201 gcataatcca cttgagacga aaatccagct ccaaaatttt catttattaa accttgcata
    55261 tacaaatctt cataaagctt acttcctttt ttaaataaca tccctacaag tatatcagtt
    55321 acaatctctt tacgtaaaag ttctttccct tttaaaccaa cattactatc tttaaaacct
    55381 atgttgaaca taggcataga tatagggaat ttttctataa cctctttttc ttttacacct
    55441 tctggttctt ctggataaaa tctttctata ctcttagaga gtctgtctac tttgtaattg
    55501 tttgactttt tagttacatc tataactttt tctacatcta agtcaccaac aacaaataaa
    55561 gccatatttc ctggattata gaaagtatta taacatttat atagctcttc cttagttatc
    55621 ttatatatac tatcaacagt acctgctata tcaattctag caggataatt tacatacatt
    55681 gccttcaagc aattaaagta tacattccaa tcagggtcat cattgtacat ttttatctct
    55741 tgtgctatta tacctttttc cttttcaaca ttttcatctg taaaataagg tgtttgaaca
    55801 tagtcaatta gatgttctaa actctcataa aaattttcag tagcagaaaa taagtaggct
    55861 gtcattgtaa aattagtaaa tgcatttgca tttactccta attttgaaaa tttatcaaat
    55921 gcatctcctc catcaggttg ctcaaacatc ttatgctcta gaaaatgtgc aataccttca
    55981 ttcactctaa ttttcttatc ttctccaatt ggtacaaatt ctaagtcatt tgaaccataa
    56041 ttagtagcta aaatagcata ctttttcata aaaccccttt taggcataaa atatacatct
    56101 aatccatttt gcaatttctc ataataaact tcttctttca atatatcatt aactattttt
    56161 tccatagaca tctcctccat taatttctca agaagtatac agtatcaagc tctatatttt
    56221 ttatagcttc aactatatct ttttttgtaa ccttttctat actagatatt atgtcttgta
    56281 cttcagaatt tgtctttgcc atagattgag agaaaacaaa atcagacata ccacctatat
    56341 tatcagttat agatttcata gaattaacta aagcaagttt actgttttct aattcttcat
    56401 cagatatatc acctgctttt acactttcta cttgtttttt tatcaattct acagctttat
    56461 cataatcttt agtttctata ccagatgata taaacatgat acttttatac ttctctattg
    56521 aagagaatat atagtaacat aaactttctt tttctcttac attaacaaat aatttagagt
    56581 gtggaccacc acctaagaca ttgctcccaa ctactaaagc ataatattta tctatgtctg
    56641 cataatccac atttgctcta taacccataa ctaacttacc ttgagttatt tccatttgtt
    56701 catctataac ttttacctca tccacatttt ttataaaatc tgctcttggt atatttataa
    56761 tttcttctct ttcaaatttt agatttttac ttattatatc tacaacttta tcttcatcaa
    56821 aattaccttc tacaactata tctataggtg atgttttaag tatgttttta taatgttcat
    56881 ataactctct tgaagttata ctatctattt catcttcata accaaattca cttacactat
    56941 atctctctcc tttacacata gcctcaatac atttatcttg cgcatattcc tttttatcat
    57001 ttattattga ttgtatcttt tctcttaaat tctctttttc aatatttaaa tattcttctt
    57061 taaacccacc atctacaaca agcgtattat ttattacttc attaaaaaat tctactactt
    57121 cttcaaatat actctcatct aaatactttt cacttatgtt aattacttta aaactcaata
    57181 cttgacgttc tccacgtttt acagcatcag ctcccataga tgaaccatat aaatcatcta
    57241 atttattgga tattgctcta gcactaggat atttagcgct tccacttgct attattgatg
    57301 gtattagagc attttttgta gtttcttttt catccaatag tctctgaaca tataaactta
    57361 taagattcga tttaaacttt tctgttttta tcaaagtaag attaatatta ttacctaaat
    57421 ttattatttt tttagtatta accatatgta cctcctattt ttatttaaac atcaatttta
    57481 aaattgaaat ttatttattt tttaattaca tatactcaca tataaaaacc ttctatttaa
    57541 ttatatcctt tttattattt tctaaaagca atatttttat ttaaattaaa tacaaatatt
    57601 atttaaatca atatgcttta aagtctagtt tacaagcttg atatatatga tgtataatca
    57661 atatgtatgt ctataattaa aacaattttg caatcctata gattgattgt ttaaagttat
    57721 ataaagaata taaaaaagaa taagagagag gacgattaat atgaaattag gcatagttgg
    57781 tttaccaaat gtaggtaaaa gcacactatt taacgcaata actcaagcag gtgcagaatc
    57841 tgcaaattac cctttttgta caatagaccc aaatgtggga gttgtatctg ttccagatga
    57901 aagattaaac aaactacaag aattatataa ttctgaaaaa atagttccta ctgctataga
    57961 attttgtgat atagcaggtt tagttagagg agcttctaaa ggagaaggtt taggaaataa
    58021 attcttatca catataagag aagttgatgc aatagttcat gttgttagat gttttgagga
    58081 tgaaaatgtt gtacatgtag atggttctgt agacccactt cgtgatatag aaactataaa
    58141 cttagaatta attttctcag atatagagat tcttgaaaga agaattaata aaactcaaaa
    58201 agctgctaag gctgataaaa ctttaggttc tgaacttgat ttattaaaat caataatgtc
    58261 tactttagaa gaaagtaagt gtgtaagaac tatggaattt acagaagatg aacaaacatt
    58321 cgtaaattca ttggatttac ttacatctaa gcctgtaata tatgcttcaa atgtatcaga
    58381 agatgattta gctgataatg gagaaaataa taaatatgtt caacaagtta aagcatttgc
    58441 agaaacagaa gatgccgaag ttgttgtagt atgtgcacaa atagaagcag aaatttctga
    58501 acttgattct gctgaagaaa agaaagagtt tttagaaaca ttaggtcttg aacaatcagg
    58561 gcttgataag cttataaaat cttcttatgc tttacttggt ttaatttcat tcttaactgc
    58621 tggtccaaaa gaagttagag catggactat aaaagttgga agtaaagctc ctcaggcagg
    58681 aggaaaaata cattctgata tagaaagagg atttatcaga gcagaaacaa tagcctttaa
    58741 tgatttggtt gagcatggta ctatggctgc tgctaaagaa aaagggttgg ttaaattaga
    58801 aggtaaagaa tacatagtta aagatggaga tgtaatatta tttagattta atgtttaaaa
    58861 tgattaatcg tatacacttt gactattata tataataact aaaaaact
//
LOCUS       DAMJXI010000017        58858 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.017, whole genome shotgun sequence.
ACCESSION   DAMJXI010000017 DAMJXI010000000
VERSION     DAMJXI010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58858
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.017"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            63..407
                     /locus_tag="PC465_001435"
     CDS             63..407
                     /locus_tag="PC465_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDF2648753.1"
                     /translation="MEIKRYEGTGRMSRTVVHNNTVYLCGQTHAEGGVIEQTTEVLAK
                     IEDLLNKYGSDKQHLLSVTIYLRDMKDFEAMNSVWDAWVEKGFEPARACVEARLAREH
                     LLVEMSVVAATK"
     gene            complement(566..2662)
                     /locus_tag="PC465_001436"
     CDS             complement(566..2662)
                     /locus_tag="PC465_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HDF2648754.1"
                     /translation="MIKFKLYISGLYSGNVIFDGDLLIEKLNPFTNKIESLKPISKEE
                     NTYYLNLTKIDLKSLFNNFDVYTKSLVNTDKDTVINNLGETHSKLNEYIWVQRNKKFP
                     LDIIIVDNKIVGFICLSRETCTILIMDGYEEYTVLKEWEKTHKNEEIYSIRFGGNYMI
                     DMKDGIKLSTDVYLPDFVDSTKKAPTILMRTPYGKENDKEIYYKYVQRGYAVVIQDVR
                     GRNESEGKWEPLIHEREDGDSTINWIVSQEWSSGIVGMLGASYLGYVQWAAASSGNKH
                     LKALVSIVTSGSPFIDIPRKGGAFVSGMLAWAFMVSRNKVDRSKMVRDDWDDVLNIRP
                     IENIPFEALGYRIEFLEEWLKRVEKDEYWDLMDWHLQKDKINVPALVVSGWYDDNSMG
                     TTEALDVIKDYEKGKRKAILGPWMHNSNTLRDINGISLGNSSLRYDLDYNYLLWFDKY
                     LKGIENNIDTTAPVEYYSVGSNKWKTEENWPIINKIDKSMYLISDGNANTSLGNGRLV
                     FDNDLEEKYDSYIYNPKDPSVQLIDMSENEVGVPNNYKDLEKRSDMLCYTSDAFSEEF
                     TVTGDIKLEFFASSSAKDTDWVIKIMDVDLDGNSIKLADGILSARFRNSFYKSEFMEE
                     GEIYKFTVITSKISNTFKVGHKIRLDITSSAKNFIFQNSNTTEGYNSIEYIEAKNTIY
                     HGGKYPSKLILPIENK"
     gene            complement(2675..3835)
                     /locus_tag="PC465_001437"
     CDS             complement(2675..3835)
                     /locus_tag="PC465_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HDF2648755.1"
                     /translation="MNTLFSNPGSILAVMTSMIALGFYLQRYKAIKSLGPALTIIIMG
                     IILSNLKVVPVSTELYGTISTYAIPVSMTIMLMSVDLKEMTKLSREPLIAIFVAVLTV
                     SIMAFLFGLVFAEKISEGWKVAGMFVGTYTGGSANLTAIGTGLNVSRQTLAAANAADY
                     VIGVPTLIFMFALPAILKNSKKFKKLWPYHVEESELEDCQNEEFMESKEWSIKDIAWM
                     LAIGFVVTEVSTILAGYFNSSFSSAARILLVTTISIIIAQLKPVKKLKGNLDLGLFVA
                     LFFLCTIGFSVDIKEFLGSTFTITLYCFSIIFASFVFHLGITRLLKIKYQYVILSIVG
                     AIADGPTSALVAASAKWNSLVSVAVVMGVIGGVLGNYAGISVAYAIKMSLGL"
     gene            complement(3854..4921)
                     /locus_tag="PC465_001438"
     CDS             complement(3854..4921)
                     /locus_tag="PC465_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide epimerase"
                     /protein_id="HDF2648756.1"
                     /translation="MKITDIKFEKLRIKLKKPVVVSFGVIEYGESVILKIETDEGYCG
                     FGEAAPLAAVTGEVLDNVLSVLLMFKKELIGKDPLDIETIHTIMDGIIIGNTSAKAAI
                     DIALYDIKGKIMNAPLYKVLGGFDSKVQTDITISIDKPEKMAVEALERVKEGFRILKL
                     KAGINPEDDIEAVKLIREAVGESIRIRIDANQGWNVNSSINTIKKLEEFNVDAIEQAL
                     PHWDLDGTAYIRNKSNTKIMIDESLHSPIDAIKAIKKNAVDTFNIKLMKSSGIYPAIK
                     INNIAEASGVNCMLGCMLETRIGITAAANLIASKKNITEADLDSFMFCEELEGISGGF
                     VMDGDIMNLVNKPGLGIEVNL"
     gene            5273..5839
                     /locus_tag="PC465_001439"
     CDS             5273..5839
                     /locus_tag="PC465_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2648757.1"
                     /translation="MLGEKMRNIRKSKKKTLSDVSKLTDLSISYISQIERDAIEPSLS
                     SLRKIAEVLDTPLYMFMDDNNTDDLVIRKEDRVMMKFPKSEMFYEIVSPMPTTEFTPS
                     ILFVEFELKPESEDAKDYIYHASEEIMVVTSGVVDICMGEKVVRLNPGDSTFIKANVP
                     HKIINPSKDTIARGYGVISPPIWPIKSK"
     gene            complement(6058..7044)
                     /locus_tag="PC465_001440"
     CDS             complement(6058..7044)
                     /locus_tag="PC465_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase"
                     /protein_id="HDF2648758.1"
                     /translation="MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNIL
                     VGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLS
                     FRGVKSGARAYVSIAGGIDVPLAMGSKSTYTRAKIGGFEGRALKKGDYINTFIQEKDF
                     TINKKLSSKYIPTYSSEIVLRIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLD
                     GESIKHLNGADIISDGISYGAIQVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLA
                     QAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAKVLNDIAV"
     gene            complement(7074..7769)
                     /gene="pxpB"
                     /locus_tag="PC465_001441"
     CDS             complement(7074..7769)
                     /gene="pxpB"
                     /locus_tag="PC465_001441"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HDF2648759.1"
                     /translation="METRYLISGDKAVVAEFGNEISEDINKKVISFMRAIEISNLKGI
                     VTEMVPTYRSLMISYNPLEIDFDSLIENLKKIEDNLESIVLPKPKIHEIPVCYDEVFG
                     IDIKNVASYNNLTVDEVIKIHTSREYLIYMLGFTPGFPYLGGMDERIATPRLEVPRTK
                     IYGGSVGIAGSQTGVYPIDSPGGWQIIGRTPLKLYDENREEQILLRAGDFIKFVPITL
                     DEFIEIEKNNLSI"
     gene            complement(7789..9009)
                     /locus_tag="PC465_001442"
     CDS             complement(7789..9009)
                     /locus_tag="PC465_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HDF2648760.1"
                     /translation="MSTKNITDKTKNKKDVGALIGAAFIMATSAIGPGFLTQTAQFTQ
                     DFGPNFSFVILITTILFIGAQVNVWRVIGVSGLRGQDIANKIIPGLGYLVAFLVALGG
                     LAFNIGNVGGAALGMNVMFNMNMTLGTVLSGLIAIFVFMSKNSNSLVDKITKFLALGM
                     IIIVGYVAISNHPPVGEAVSRMVKPENPKGLIFPIITLLGGSVGGYITFAGGHRLIDG
                     GITGEENIKEITKSSLLGILVATMMRVLLFLAILAVVSKGLQLDPENPAASAFKFSAG
                     AIGYKFFGLVLWSAAITSVIGAAYTSVSFLKTLNPFIDKYEKYFIIAFIAISTLIMAF
                     IGKPATLLILAGALNGLILPITLGIMLIASKRKDIVGDYKHPTWLLIFGLIVVLISAY
                     TGITSLSSLGALFA"
     gene            complement(9038..9829)
                     /locus_tag="PC465_001443"
     CDS             complement(9038..9829)
                     /locus_tag="PC465_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LamB/YcsF family protein"
                     /protein_id="HDF2648761.1"
                     /translation="MYKVDLNSDLGESFGTYKIGLDEEVLKYISSANIACGFHAGDPS
                     HMEKTVQLAKKNGVKIGAHPGFLDLIGFGRREMKITKQEAKDYTKYQLGALMAFASSN
                     GCNIQHVKPHGALYNMAAKDKELAMGICEAIYEVDKDIILLGLYNSEMINSAKEIGLR
                     FANEVFADRAYDNNGFLVPRSVEGAVIHDTKHAIDRVVRMVKEGTVETLTGEVIHIKA
                     DSICVHGDNPKAIEFVKEIRKRFELESIEVCPLENIEVCSSENIV"
     gene            10417..11046
                     /locus_tag="PC465_001444"
     CDS             10417..11046
                     /locus_tag="PC465_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2648762.1"
                     /translation="MDKNYTMPIYQKIALDIANKIYTGEIQEDSVLFGRSVLAGKYNV
                     SPETIRRAVKILEDIGVVKSIKGKGVIVLSPDKASSFIKKYRDITNISSYKSTLYNLI
                     DTKSNLENEILDTINKILDYSNRLEIINPLVPVQFTINSNCKYIGQTAAQTKFWQNTG
                     ATIVAIKRGEELIISPGPYIEFLEGDILLVVGDQHIYNSIPMFLYENEK"
     gene            complement(11160..12674)
                     /gene="glpK"
                     /locus_tag="PC465_001445"
     CDS             complement(11160..12674)
                     /gene="glpK"
                     /locus_tag="PC465_001445"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HDF2648763.1"
                     /translation="MEKKYVMALDQGTTSSRAILFNKKGEIVKIAQKEFNQIYPKAGW
                     VEHDPMEIWGSQSGVMREVIETAGIRPEEIASIGITNQRETTVVWSRYTGKPIYNAIV
                     WQCRRTSEICDELKNKGLEESIKEKTGLLIDAYFSATKVKWILDNVEGAREKAEQGEL
                     LFGTIDTWLIWNLTRGKVHVTDYSNASRTMMYNINDLEWDEDILRELDIPISMLPLVK
                     PSSYVYGHTDERMLSGAKIPIAGCAGDQQAALFGQNCVEEGTAKNTYGTGCFLLMNTG
                     SNIVKSKHGLLTTIAWGVDGKVTYALEGSIFIGGASVQWLRDELKIIESAKDSEMYAN
                     RVEDTNGVYVVPAFTGLGAPYWDMYARGSILGLTRGAKKEHIVRATLESIAYQTKDVL
                     EAMQNDSKLKLKSLKVDGGASNNNFLMQFQSDILNVDIDRPKIVETTALGAAYLAGLS
                     VGFYIGRNEITSKWSVEKEFNPNMSEEKRCKLYKGWKKAVSRALSWEKEDELDI"
     gene            12918..13460
                     /locus_tag="PC465_001446"
     CDS             12918..13460
                     /locus_tag="PC465_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2648764.1"
                     /translation="MPKILENVKEDILKVSRDMILEEDYSYISIRKIAQRCGISAGTV
                     YNYFNSKQEIIEYITKSEWDLLIRRIEYSNKNTEDYIKKLNIIFTEIRNFINKVHNIQ
                     YNDFLNTFETERFFEMKKHKDDFHEQLSNKVYEALEKESFFNNDKLVCNIIIKMFFSY
                     STYLHIEFEDLKPYIEKLIH"
     gene            13474..15966
                     /locus_tag="PC465_001447"
     CDS             13474..15966
                     /locus_tag="PC465_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2648765.1"
                     /translation="MNHNTSIKNKDSNPKIFLVLTLYLLGIFMGAIDTGIVSPARTII
                     QNSLGVNEKTGIWMITIYTLTYASVIPISGKLADKIGRKYVYLVSIFLFGSGSLICGL
                     SSLFSNFYILLIGRVIQAIGGGGIMPIATAEFGTTFPENKRGMALGLVGATYGIANIL
                     GSSIGSTILSIFGTQNWKWLFFVNLPICLIILIGGVFCIKNNKSESKEKIDKLGTLML
                     ICIIVSLLYGLMNIDFFNFKNSIQDISVYPYLLTFIVLIPIFIFIENRAKDPILSFEY
                     FLNPRILIVLILSLIVGIGMMGMVFVPQYAENALKINAGSGGYFVAILGLFAGIAAPL
                     SGRLIDKFGAKKILLLGFSVSMIGSLYLVLIALKTNTVFSVCVSLIFMGLGMGFTMGT
                     PLNYMMLSNTRLEESNSALATLSLIRSIGTSISPAIMIGFIAHAGLSVQDNIMDLVGK
                     PSTPKIVQLEELENMIDDLKSDPEMAKNLKNVSIPNMNDTSNINMDMTGGKLPKSLLN
                     KVQSADTTNITNITKEISTTMFDEKVPSIITKIQKNVQKGIDGTQSGINGIEDGENKL
                     NSGIKGVQTGIDNMVKARAGINQGIDGVKKGIAGVDKGIKGMEQGLEKQDEAIKELTT
                     AYNKIPTTEKTPTDNENNSNEQNQSNTSNSESDDTKNDSTENKNNNSSENKPNVNEQK
                     ESLNAQIQQLKKTRDDLNTKLQKNKTQKNELSKKLRSMESQKKELQSKLNNSISQKKD
                     MEKSLDTMQQQKKSLQAVLAKTQEVKTEIPKAFDKSKLDYINSIENNRTKIENTLQST
                     LNSGFKQMYITVFCVNLLAFIILLFYKENKTR"
     gene            16387..16785
                     /locus_tag="PC465_001448"
     CDS             16387..16785
                     /locus_tag="PC465_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2648766.1"
                     /translation="MDTLGKRIAYLRNSKKLTQRKLMDILKFENLGKYETGDRKPNCD
                     ILMSIADYFNVTTDWLLYGKEKVNVNSSVKEDKEDYLHVTNDEMMILNLYRQLNERDK
                     IKIEGILELKISEYKDLKKHSSNNNEDKMV"
     gene            complement(17002..17211)
                     /locus_tag="PC465_001449"
     CDS             complement(17002..17211)
                     /locus_tag="PC465_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648767.1"
                     /translation="MCKLDSDGVIECCRAIDDFITALSNIKSLNMERLNTLTKYSSTC
                     SILLKEGNYEGCTIVYRKMLEELKT"
     gene            complement(17243..17452)
                     /locus_tag="PC465_001450"
     CDS             complement(17243..17452)
                     /locus_tag="PC465_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2648768.1"
                     /translation="MDARKKWIPFLGVQVKQRLIELNMTQRELAKKIGVNENYLSAIL
                     NGRRTGKKYKSSIYQLLNIEYSEDD"
     gene            17751..18170
                     /locus_tag="PC465_001451"
     CDS             17751..18170
                     /locus_tag="PC465_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2648769.1"
                     /translation="MDTLGERIVYLRKAKNLKQYELEEMLGCDNLSKFERNIRKPNYE
                     ILKSIAEIFNVSVDWLLNGDNLSHKSDLICDSSSNYPLNSINSNEIKLLNNFRKLNDY
                     DKAKIEGMIELKLHEYEKEKDLGKIEYNKNKDEKIDK"
     gene            18398..18853
                     /locus_tag="PC465_001452"
     CDS             18398..18853
                     /locus_tag="PC465_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648770.1"
                     /translation="MGLRDKFAQSFARSKTMSGPEKKANEIMGKLLLKKAILPIVLMF
                     VIIIAGAMLKINSWVTLGINLVIAVGAFFYIRNSSKKYQNFKPYVGNLISLEKKGKKE
                     YVAIIKQGKLPVKLQIAYGGEDLEHVKKNQMVQISYNPDAKIAILVNRQ"
     gene            complement(19009..19821)
                     /locus_tag="PC465_001453"
     CDS             complement(19009..19821)
                     /locus_tag="PC465_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDF2648771.1"
                     /translation="MAEQKYYTLLTKAGKASIANATALGKKVDLVKLQLGDGGGSEYS
                     PTEEQTSLKEVVWEGNISNVKIDDDNSNWIVIETVIPGSIGGFMIREVGIFDSENKLI
                     AISKYPETYKPTADSGSVKDLIIRIILVVSNTSSVNLKVDPTVILATLKDIQELDKKI
                     DTTKITLTSGIETTKIELNTKIDNTKTDVTSKIGDTTLLNTTDKTSLVNAVNEVKEGL
                     DSIETTAEKTSYDNTVSKLAATNVQGAIDELCTSVNTARISLINDIKDMLPI"
     gene            complement(19823..20440)
                     /locus_tag="PC465_001454"
     CDS             complement(19823..20440)
                     /locus_tag="PC465_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HDF2648772.1"
                     /translation="MKLIDKLPSFYKNYMVEAIQDSYDSELSSLKENIDDTINQMFVN
                     TSTWGLDMWESILCIQNNEDLNYETRRSNIKAKMRSLGTTKLKVIKNICEAYTKTDVE
                     VTVLSNEFIFILEFIVNNCSYNSIVELDKVLENVKPCHLEHKFKMILLNKNELFCGTA
                     INTGETVTVYPWTPSNIEIFGEITISTGNDRSMEKVILYPKQEAI"
     gene            complement(20440..21489)
                     /locus_tag="PC465_001455"
     CDS             complement(20440..21489)
                     /locus_tag="PC465_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HDF2648773.1"
                     /translation="MYSNQTYETIKNRTLKNINLDVYKGEGSFLNDMVSGNTFELSKM
                     YVELSNIYKMAFIEDTYNQLLDKRVNEFGVYRKLGTEATGEVEFIGENGVEISNGTII
                     SYKDLSFVVIKDIVIGGEEGNISPVEALEIGTRYNLPSDCEFKVNDNIFGIEKITNIN
                     KFSGGTEIETDEELRERFFRVQKNQATSGNKAHYEEWALEVDGVYNAKVYPRWNGAGT
                     VKVLLFGQNNQAVEEEIITKCREHIEEEMPIGATLTVTTPIPLNITISASMELESGYT
                     LDMVKNSFIENINQYFRSITGEIVYTKIMGILISTSGVHDLSNLLVNNSTDNITIEDD
                     KIPSVTTLDFSEVEV"
     gene            complement(21482..21913)
                     /locus_tag="PC465_001456"
     CDS             complement(21482..21913)
                     /locus_tag="PC465_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HDF2648774.1"
                     /translation="MSNTIFPFIGVPEDYEIPKKEELGLFREVAWNFEKDEPIVENGD
                     FKIIEKNEAIKVWVYKCIKTNKNEHEIYSNDYGTELTDLIGQKYSKGLTESEASRYIK
                     EALLMNPYILQVDVVNTNFKKDILGAYIKISTIYGEVEINV"
     gene            complement(21913..22239)
                     /locus_tag="PC465_001457"
     CDS             complement(21913..22239)
                     /locus_tag="PC465_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HDF2648775.1"
                     /translation="MANSINEFIGIIRKEGKYYNKPSFFVGKIINKLPDLKVSMNNIV
                     LDKDNLLIDNWLFDRATKSFIITQSNNHTHELNESLTNQLDKGDTVIMFKVGEKFAII
                     SKLVSL"
     gene            complement(22253..23770)
                     /locus_tag="PC465_001458"
     CDS             complement(22253..23770)
                     /locus_tag="PC465_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2648776.1"
                     /translation="MIINRSKDSSSVNINFTAKDMGFLLLQSEVSYNFKDKLVEDIAK
                     QVFADNKLAIGNIPKTNVKYTKMFISVNGYDTIMSAYTEASKTTKKKYMIEANLDKFN
                     IIEKGTVTLNIIFEEGFNLINTTFSESMENVKNKVLLVDQYGNKISEKVNNSLFKEVN
                     VIMQKVIQQQENSTTDIENEFKGIERTCSLKGYGDTSCITGRGVKVKDSYTKLVGLFY
                     IDTDKHTWQNGDYQIELELNFQNIMDEKSVGQDEQKEEISDLSGNGALNGREVKAEFT
                     AYYPSNDPMEGGLYQKMDGKKLVPSNNTCAAPEVLKFKTQIQVKGTGTNIDGKTYTVT
                     DRGGAIKVVNGIYKIDILMSSKKECYNFGRRKGTIIIGDGTGYTNSTGKVKELISIAK
                     GKKGCKYVWGASGPNTFDCSGFTQWCYKKIGINIPRVSRAQGSVGKQVEKKSLQPGDL
                     VFFSSKGPKGTIDHVGILIGNNEFIHSPHTGDVVKISSLKGSYYSKNYVGARRFL"
     gene            complement(24039..24461)
                     /locus_tag="PC465_001459"
     CDS             complement(24039..24461)
                     /locus_tag="PC465_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648777.1"
                     /translation="MEMWLRQAEDRFRFPVIPPSISINGKSTINSSNILKVGEIATFG
                     GVALKSINISSFFPNKEYSFCNYKGFPSPYDCVNKIQRWMNEGLILRFTVTETNINME
                     VIIEGFSYEERDGTRDVYFSLDLREYKRLQILRANPKK"
     gene            complement(24461..26791)
                     /locus_tag="PC465_001460"
     CDS             complement(24461..26791)
                     /locus_tag="PC465_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648778.1"
                     /translation="MGNVREEGINMYITDNYTPKMNQIISVTEALKRVTVSVSPSVNT
                     MANSIKSSMASASSSINSINSSIKKMTSSIKSLSNSIEKMNGSMNNSGSSNKDFSEGL
                     ETLGRSAENARSKLVRLSQVANSKKGRDTHKNVKAKNNESKNNKSDKPEKIKTVQDIV
                     KRVKTQTVDTSKKIVTGKLPELKNKVFNSNLVMGVKGNNIVQNTLNILNKIKNSKWIS
                     SISVKDLAKNVLIGTLSKLKQFAGRMWTGAISIKDKASSILGGIKDKISDITNGFSIG
                     GAVKKGVDLVGKGQNQKAVLTNVVQRTTGVKDKIEAKSEANNYYNDVIKDIALKSPFD
                     PSEVISMSTKAMTISGGKIDKSKDITQAMVNVRALNMETSSDQDVSAAFVSASKGNMD
                     ALNTLVGENYKTLDDALEGIKEKQNGLANEMAGTIPGLLSSASTYIDMGLNSMIEPFD
                     SILEGGLKKINSFLEKVPSGIGGFSQKVADVMNGKKIAENKQNPIETQVATALGHVPQ
                     SIGNTSQMLVQNIDFTALTNSLLPVVNLVNVLLDSINNKSPVAQGIISIFGTVVTTVF
                     QLIGPVVEAVSPIIMRIFTFLGEYAPQINNFIETLGVIWKTVWETLGPLLETGWKIIE
                     PILGAFFNILDKVCKIVKDICKWWQTMINKIKNGSITGTVLNLVEKSKKNYKDNPYAG
                     TKAGDSGKAYSSKKGNNAFGLNYVPYNDYQTRLHEGEMVLTKQEANQYRSRKNGGNIN
                     IAKLADTIVIREEADIEKITSKLVASIQVAQLGGVL"
     gene            complement(26791..26958)
                     /locus_tag="PC465_001461"
     CDS             complement(26791..26958)
                     /locus_tag="PC465_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648779.1"
                     /translation="MYYYWKKKGIRPSLFYTMDKGELKLIEAFFALEIEEEVEKMKHG
                     YGVCPLTGGGI"
     gene            complement(26985..27431)
                     /locus_tag="PC465_001462"
     CDS             complement(26985..27431)
                     /locus_tag="PC465_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF2648780.1"
                     /translation="MNENGLSKNINIVDLLLNADTENLERPSTIVELKRLSTIFGQEF
                     KVMCRALTISKDEEIQNTCLKIDENMKTDIDLPEMQMLTIIEGVCDLDGKLLFKNKEL
                     MDKFKAPTPKELARKLLLPGEITNLYRILQDVMGYGKNAVIEEVKN"
     gene            complement(27545..27973)
                     /locus_tag="PC465_001463"
     CDS             complement(27545..27973)
                     /locus_tag="PC465_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HDF2648781.1"
                     /translation="MANMEARNVMSGTWGELWLDGDKVAEVKKFQAKMEFTKEDIIIA
                     GQMGTDTKYMGYKGKGSITLYHVSSRMHKLIGEKIKRGSEPRFVAISKLNDPDSYGAE
                     RIAVKNIAFDDLTLADWEVGVKGEIEAPFTFTEYDFLDII"
     gene            complement(27987..29051)
                     /locus_tag="PC465_001464"
     CDS             complement(27987..29051)
                     /locus_tag="PC465_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HDF2648782.1"
                     /translation="MAIGLPSINISFKELATTVKERSARGIIAMVLKDAKALGLNEIH
                     EKEDIPVDLSAENKEYINLALMGNVNTPNKLLVYVIEGEADIQTALDFLETKEFNYLC
                     MPKAVEADKTAIKNWIIKLRDIDKVKVKAVLGKVVGNHEGIINFTTEDVLVGEKKYSV
                     DEFTSRVAGLIAGTPLSQSVTYTKLSDVVDIPKMTKVDAESKVNKGELILIKEAGAIR
                     IARGVNSLTELTAEKGEMFQKIKIVDTLDIINNDIKKVIIDDYIGRVPNSYDNKCILI
                     VAIKEYLEELEKEELIEVGSLVDIDIEAQKQYLKSKNIDISNMKEQEIREANTGSKVF
                     LKAKIKMLDAMEDIDLSIEI"
     gene            complement(29056..29499)
                     /locus_tag="PC465_001465"
     CDS             complement(29056..29499)
                     /locus_tag="PC465_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648783.1"
                     /translation="MLKYKEILETIIEILKKNFTESIFIDDESVQGSEGSCFFVSILS
                     VICTPVMLNTNNKDIVISIKYLPKPQSKSIRMYEVSDELNKLFNRNIKVTDRKLNITK
                     LEQSIKKEESIYVLNFTLTLNYLDSVYEEDVVYENMEEINLNLGE"
     gene            complement(29748..30188)
                     /locus_tag="PC465_001466"
     CDS             complement(29748..30188)
                     /locus_tag="PC465_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648784.1"
                     /translation="MENKKDILFKETDKRLHNYKYLDIKIKNINLDIKRCENEYSGCG
                     AMVYTEKTSNTYNISSSVENEVLKREERLRKLKMEKEDIEIEKEKIENALTCLNDIEM
                     EFFNLFYNSKTKNNMTYISMKLHLDRTSCYNLKKKMIFKLSEIL"
     gene            complement(30293..30490)
                     /locus_tag="PC465_001467"
     CDS             complement(30293..30490)
                     /locus_tag="PC465_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2648785.1"
                     /translation="MFKNNLKYYRKCKGMTQIQLARKAGITNDYISQIERGIKNPGLL
                     MAKKISSILEQNIEEVFFIQL"
     gene            30659..30979
                     /locus_tag="PC465_001468"
     CDS             30659..30979
                     /locus_tag="PC465_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF2648786.1"
                     /translation="MFAKRLRELRKEFGLTQRELGEKVGVSQRVLGYYETENRFPDEH
                     ILNKLADVFNVSVDYLLGRTLVKENIDTVAAHRKNPHEELPEEAQEQLNDYIEFLLNK
                     YKKK"
     gene            31061..31567
                     /locus_tag="PC465_001469"
     CDS             31061..31567
                     /locus_tag="PC465_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648787.1"
                     /translation="MNNLDKLFELASQEEIVIHYTTYIAGDLEGLYINKHGIKIISLL
                     SNLKQNSKKLTSILAEELGHHFTSLGYYVSSYNDYYTKIIIDKCENKALKWACEFLIT
                     EEDIINIINSGITCVYEMADILNVDITFFQKRLEFLSLKKQSLQLGNNKYLILTNLPY
                     FYIFDPIS"
     gene            32268..33023
                     /locus_tag="PC465_001470"
     CDS             32268..33023
                     /locus_tag="PC465_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2648788.1"
                     /translation="MEKKVLATVGEKEITNIDIENALKSLDPYQAMQFKTEEGKKHLL
                     NDLVNQELFFLDAKEEKLDEEEIFKLEMKKIEENVLKQFAINKVLSSVNVTEDEKVKF
                     FEANKSSFSKPESATAKHILVDSDEKAKEILAQIKSEEISFEDAALKHSSCPSKDMGG
                     DLGTFGRGQMVPEFEEAVFSMAKGEVSEPVKTQFGYHIIKLEDLQESTESTFDEVKAE
                     VEKSLLYQKQNEVYGNKINALNAKYGNLVKYND"
     gene            complement(33166..33594)
                     /locus_tag="PC465_001471"
     CDS             complement(33166..33594)
                     /locus_tag="PC465_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDF2648789.1"
                     /translation="MNILFFLTPKSEVAYIYEDYTIRQALEKMEYHKYSAIPIISKDG
                     KYVGTITEGDFLWTLKNDLNLDLKGLEDVPVTDINRKMDNSPVSINADIEDLVIKSLN
                     QNFIPVIDDQDTFIGIIKRRDVIGYCYEIIRGYKNLANDN"
     gene            complement(34015..34215)
                     /locus_tag="PC465_001472"
     CDS             complement(34015..34215)
                     /locus_tag="PC465_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF2648790.1"
                     /translation="MKTGVVKWFNNEKGFGFISVEGEGDVFVHFSAITGDGYKTLEEG
                     QSVEFEVVDGAKGPQAANVVRL"
     gene            complement(34398..35567)
                     /locus_tag="PC465_001473"
     CDS             complement(34398..35567)
                     /locus_tag="PC465_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HDF2648791.1"
                     /translation="MGGVALKILKNKNKYIKGIMAFVFLSLATTAGVFLINDLSMKNM
                     EEKVMESANVEGDDVKDQYKLLLENLFDYRNKAILEKNENILKGLYETDKKFGLWAYE
                     NEVKKMKYLENWSSKQGVKFKDIKTRVKIKKIKEKEKDLYGIICSVSTEYKYSYENQK
                     DKENAFRIGTYHYLNVKIIDNQYVITKEWYTDPFADSLNLENIKSDDIRNYIGQQDGV
                     ELQLTDEQKKAIDYAHKYCGAAADEEHGMKFNPNYRDYNPEGGDCANFASQIMFESGR
                     FKKNSIWNYSERAGTKAWVNAQAFKNYALYSGRGSLIAKGSYEEVYKEAYNLRPGDFV
                     GYEKKGRITHVSTVTGLDSRGYPLVTCHNTDRMLVPWDLGWSDKSIRFHIIKINY"
     gene            35803..36624
                     /locus_tag="PC465_001474"
     CDS             35803..36624
                     /locus_tag="PC465_001474"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HDF2648792.1"
                     /translation="MQKKVAAINDLSGIGKCSLSVAIPILSALKVQCCPFPTAILSSQ
                     TGYPEFTFLDFTDEMVKYSNVWKNLKVNFDSIYSGFLGSKHQIEIVANFINDYPNAFI
                     VVDPVMGDNGVMYPIFTEEMRQEIKELVKHSDLTTPNLTEACFLTGNDYTKSDYNRDE
                     LIHIAKSVSDLGPSKVVITGILEDDNILNLAYDRDNDHVFFTSVKYNNCSYSGTGDIF
                     TSILCGMLVNKHDLGVAVNTATDFIYKTINYTSQFDTDRNDGVMFENFLSDLTNI"
     gene            complement(36700..38088)
                     /locus_tag="PC465_001475"
     CDS             complement(36700..38088)
                     /locus_tag="PC465_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase"
                     /protein_id="HDF2648793.1"
                     /translation="MLGGKKSNNKKVEKLRTIFIKYLSLFFIMTISIVLLLMLSFSVL
                     LSSGVILPANYAEKQFNKYKEQIISSEKVTEDIIPSIYEYGVYTLDGNLISGTFNKKE
                     SKEVWNLMRDIEERHAYSESYIKFFKKDEVFIIKYKIVSEYSSPILRAYLPKPETLGM
                     IIFSIIFFIEIVILSKVFGKKFNIEMELLKNTTEKIEQQDLDFVVESSKIYEINNVLF
                     SMDKMKLALKDSLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIEINENPELL
                     EYMEYISKGVTQIEKYINTLIDISKTENGYILNKEAISMSEFIKDVLVQIEALASTKN
                     LDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVCNKYLKFVV
                     TDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLYIVNNIVQKHNGTLCIENSVKT
                     GGAMVTIEIPIV"
     gene            complement(38223..38981)
                     /locus_tag="PC465_001476"
     CDS             complement(38223..38981)
                     /locus_tag="PC465_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HDF2648794.1"
                     /translation="MRQLIRIFCSDLIKLKRNFIILMHICIALMGMGLFLWYYKVSGA
                     DNILKIVGYLQVIAIAFPLLSGVVCSMFVEQEYYAGNYKHMLTTSNPKYLTLISKYII
                     LVCLGFVATLVSVLGFKFGISKAYFTSSFYMISILILIGCNLFEYILHLFLSLRFGKG
                     ASIGVGIVEMLLSALLLTGLGSGIWQYFPCAWGVRFITIWSSFSSSKTVEYIKVESIK
                     AYQSTGLICGFVTILAFVILCIWFSKWEGKKSEE"
     gene            complement(38983..39699)
                     /locus_tag="PC465_001477"
     CDS             complement(38983..39699)
                     /locus_tag="PC465_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HDF2648795.1"
                     /translation="MERFIRVEFQKMKGTFGMKLIWIVPVFCILLCGLGGGQNAAFNW
                     WYTTFLPGALTLISSLIVLKDEKSKYRGILPLPIEMKDVWTGKMIYCIICCFIASIIS
                     AIGVVFVGIIYKETISIGQNIIATILIILLFMWQIPLCMFLASKFGIFVTVLINMFFT
                     IVGVAVFSTTEMWYMFPYSIPSRLMAVVLHILPNGLPVPEGSEFLNNAVILPGVLISI
                     VLFVLFALATRVWFNNREVK"
     gene            complement(39701..40408)
                     /locus_tag="PC465_001478"
     CDS             complement(39701..40408)
                     /locus_tag="PC465_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF2648796.1"
                     /translation="MSNYILQVKGVSKKFKEQMAVDNISLAIKSNSIYGLLGPNGAGK
                     STLLKMITGILNPTSGKIMFEGHRWTRKDLSNIGSLIESPAIYENLTARENLKVHTTL
                     LGLPDSRIEEVLETVDLRDTFKKRSGQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL
                     DPIGIEELRELIRSFPKQGITVILSSHILSEVEQVVDEIGIISNGVMGYQGEVSKEQN
                     LEKLFMKVVAENRKRGE"
     gene            complement(40524..41060)
                     /locus_tag="PC465_001479"
     CDS             complement(40524..41060)
                     /locus_tag="PC465_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2648797.1"
                     /translation="MNKIAVSFLIIATTLLSTACMDYSISAVELVDSKESAVVKKDED
                     AKEETTSKMINSKKTTKIPIEIISKDEKIVKYLQIDEESSLKDKLRLILDTLSNEYFN
                     GLDMEVEVKEKDNLVKINLIEPDKKSRVSWKDDYLNEQNIIYTINNIIKNVIQEEDNS
                     IWIEEVEIYYNGKLIELR"
     gene            complement(41162..42232)
                     /locus_tag="PC465_001480"
     CDS             complement(41162..42232)
                     /locus_tag="PC465_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HDF2648798.1"
                     /translation="MNKKLAIFAAVLLVIGIIGTTWSGILVMPSLINFGLEKEAEFKK
                     ENKLYQEKVNIDKLDIAVDNINVTIKKSSSEDVRVTTRGNNEFYKYNVTLKDKTLVVK
                     GERKYENKIKKIKNFDQLLNTSINSMFSHDYREIIIYVPNNVDINASSISSHLFVYDN
                     VASNTITYKTSYGGFSRAITENKVNRLENLNLISNNNLHLSTKSILGVKNVNIESESL
                     YISSENEDVFINNIEEYIPENVNIKEKIGRNSNYESEFYLYSDMPIAKFLDIEVPNSK
                     VRLDIPVNKYKFNCDIKSKEAIEEFNNDEEYDNDSYDYEHDEEHSNKYRNTREIKGLL
                     NKNLSNLEKEYTIKINSNSLEL"
     gene            complement(42225..43307)
                     /locus_tag="PC465_001481"
     CDS             complement(42225..43307)
                     /locus_tag="PC465_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HDF2648799.1"
                     /translation="MNLNKTEFLEILKDYLKKDFSESEVNDILRDYEEYFVDGLIEGK
                     SDMEIIASLGSPKSIAKELILQTKEKNIEEEKIINTDVLNDKFSKFKSDMKKGYSILK
                     DEAKEKYSKSKENIDGKIMNTDILNGKFSRFKSNVKKDYSILKDEAKEKYNKSKENIN
                     DKLTPSIEEGVGGLSRQVIKGLLVVLSLFLIVPAFAFVCAIVSATIALVCSLIAFVIL
                     IPFVIKFIAMVPDVMMFCIFATIAFVGLEILAWQILLFAIKLGKQLLNNYIHWIKRKN
                     IYIKANEKMEKRKKATLNDEDLNKDINEDLNKDINEDSYNNDYYNREEESIKETDEYN
                     DDSINFEAIYKDLEDIENKKGEDKHE"
     gene            complement(43294..43626)
                     /locus_tag="PC465_001482"
     CDS             complement(43294..43626)
                     /locus_tag="PC465_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF2648800.1"
                     /translation="MNTQFRKGVLEICVLALISKKDMYGYEIVHNISKVIDVNEGTIY
                     PILRRLTKDLYFETYILESNEGPARKYYRITSLGKENLSNLMEEWREFVKAVEILISE
                     DEGGNELE"
     gene            43825..44946
                     /locus_tag="PC465_001483"
     CDS             43825..44946
                     /locus_tag="PC465_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosyldiacylglycerol synthase"
                     /protein_id="HDF2648801.1"
                     /translation="MKDDKTILILTAQFGAGHISAAKAVKECIIEKYSNYNVVIQNFI
                     NASIPMMNKPMVKLYENNTKYTPGLYNYYYYFKKSFDSRHDLSHKLYTPKLSEYIADI
                     NPDLIISTFPLAAACVNNFKIKNPDINIPTLTVITDVVDSMEWVFENTDLYFVPSPEI
                     KNRFFQKGINPDSIKVTGVPVDKRFQIESKELCCDKYRLLLLGGGRGLFDIDEDFMHW
                     IDEFIEEHSNSIEITIVTGKNKKLYDNLTHKKPLKNIKVLGFVNDMYNLIRECDLMLT
                     KPGGATIFEAIQSQTPVLVKMPKVGQEIENAKFIIDKGLGMIYSDDLDLKNIFYKLVS
                     NEFDSIINFMKKNLKEFKTVIHPEKIADYISELIDNHYS"
     gene            complement(45074..46972)
                     /locus_tag="PC465_001484"
     CDS             complement(45074..46972)
                     /locus_tag="PC465_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HDF2648802.1"
                     /translation="MDSLLYVIEKDKHTNEELREILKSNKNIRFVSLMGVDLGGNATD
                     EKIPVELFLEDIDKFLESAIQTDGSSVELYNIATLNNAKVDLMPDKSCHWYVDYNMEY
                     IDEEVGLPVGTLKIPAFLIHDNKKVCSRGVLQKADKYFKKSMYEIFREYPHVINNIGI
                     DSVDDIEEIMLTAATELEFWVNTPEDKADLEKLYVSQSLKEQYWKRTHGIIRTCLEKS
                     LIILQKLGVNPEMAHKEVGGIQSSISIDGRTNHAMEQLEVSWKFSTPLQAADNELLVR
                     DVIEDVFTSHGLEVTFKAKPIHGVAGSGGHTHVGVSAKLKDGSIKNLFAPKDLKEDYL
                     SELGYGALMGLLYNYEVLNPIVTASNDGFNRLVPGFEAPVCIVTSLGHSYEIPSRNRS
                     VLVGLIRDMKNPKTVRFELRSPSPLSNTYLVIAGCYQTMLDGIKAAAKSGLSTKELEK
                     ELSKNVGEESFYLEKDRAYRDENDVFEHYSLEERNARFGIPPATVYENMKNLEIYASK
                     LKSLKQGDVFTDSIIESFKIGAIDKWQKKLKTRIIEAGIQKIRSIVKIHTKENMDALD
                     EVVWNSISDLKFNIMKDTLTRESLFTRVREAIENKDYQTASDLQIELKRSMEEIQQLY
                     MQYKKNIY"
     gene            47287..48063
                     /locus_tag="PC465_001485"
     CDS             47287..48063
                     /locus_tag="PC465_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HDF2648803.1"
                     /translation="MEYIIFDLEFNQGFDKKLNKTVSNEKCPFEIIQIGAIKLDSKFN
                     IIDTFNSYVKPTIYKDIHPFISRMTNIKNSDFNDSPTFPEVYNNFIKFISSQDPILCV
                     WGAGDLKELYRNINYHKLPSNSLPKSYINIQQHASKYFNNPAGKSIGLQNAISILELD
                     EKMSYHNALNDAYYTAKVFIKIYNPSIVPDIYLYTSIKPKTIRYSNKKRVDYDKLFDE
                     FRKILNRELTKDEKKIINLAYNMGKTNQFTLENVKQRKNK"
     gene            complement(48155..48907)
                     /gene="xth"
                     /locus_tag="PC465_001486"
     CDS             complement(48155..48907)
                     /gene="xth"
                     /locus_tag="PC465_001486"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HDF2648804.1"
                     /translation="MKFISWNVNGIRACVGKGFLDFFKEVDADIFCLQETKLQEGQIE
                     LDLPGYFQYWNYAERKGYSGTAIFTKKEPLKVMYGINIEEHDKEGRVITLEFEDFYFV
                     TVYTPNSQSELKRLEYRTRWEDDFIDYLTKLDNHKPVIVCGDMNVAHKEIDLKNPKNN
                     MKNAGFTKEEREKFSKLLDSGFIDTYRYFNPDKEGVYSWWSYRFNARKNNAGWRIDYF
                     CASKKLEDRLVSADIHTEILGSDHCPVELEIK"
     gene            complement(49068..50018)
                     /gene="galT"
                     /locus_tag="PC465_001487"
     CDS             complement(49068..50018)
                     /gene="galT"
                     /locus_tag="PC465_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HDF2648805.1"
                     /translation="MKELRIDPITNDVVIFATDRLKRPLDTADIPNEDEETNEYDEEC
                     PFCKGNEAHATDALFEIDSEEGWLVKSVYNKFPIIDDMARDVYGVHEVMIESDKHNRS
                     FYNMSQKEFEDVFFMYRNRFRDLSKDDKVEYVSIFKNFLRKAGASLMHPHAQILSMSF
                     IPPEITNELLVSKEYYDSNKSSLYDDLIENEISLDRRVVYNGEAFLVLIPYATKYSGE
                     VRIIFKDKIEFGELNDNNIQELSTIFEKLFKKLYNINGYMPFNLCIHTHPTKIETKSY
                     FNVHMHIIPRKYNFGGFELGTNMYVSSMSPEDLTKKLKID"
     gene            50403..51599
                     /locus_tag="PC465_001488"
     CDS             50403..51599
                     /locus_tag="PC465_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2648806.1"
                     /translation="MNYSNRVSAMQASPIRKLVPFAQAAKDKGIKVYHLNIGQPDIKT
                     PKGFFDAVKNFDSEVLEYATSEGIPELLEALQNYYKTYDMNFEKDELLVTNGGSEALL
                     FTMMAVCDPGDNLLVPEPFYTNYNGFGQSVNVEVNAVTTKAENGFHLPSKEEILSKVD
                     DKTKAIILSNPGNPTGAIYTKEELNILAEIAKEKDLWIIADEVYREFVYDGLEYTSCG
                     NLEGVQDRVIIIDSVSKRYSACGARIGSIACKNKGLIAQILKLCQGRLCVPTLEQIGA
                     VELYKTPVSYFKEVNEEYKKRRDVLYNELMKVEGVICKKPTGAFYIVAKLPVENAEDF
                     TIWMLKEFNKDNETVMVCPAEGFYATPGLGRDEIRLAYILNEKDLHRAATLLKEGLEQ
                     YVALQK"
     gene            complement(51934..52386)
                     /locus_tag="PC465_001489"
     CDS             complement(51934..52386)
                     /locus_tag="PC465_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2648807.1"
                     /translation="MNYIVKDTISFLVKTFPKIYSSLYLEDLKKFAPDYNVNKTQLRA
                     LVFIKNYGVISMTDLCSKLNIEKGSLTSMVDDLTDKKYVTRKRDLVDRRKYLIDITEE
                     GDKIATDFMDKLSDGLGEKLSKLTEEDRKKYLEAINTLQYILNKEEFR"
     gene            complement(52698..54143)
                     /locus_tag="PC465_001490"
     CDS             complement(52698..54143)
                     /locus_tag="PC465_001490"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HDF2648808.1"
                     /translation="MIDNKYTTYSNPLTDRYCSKDMSYIFSPQFKFSTWRRLWVALAE
                     GEHELGINITEEQLDELRANIDNINFDEARKIEKEVRHDVMSHVKAYGLQCEKAKGII
                     HLGATSAYVGDNTDVIQMNEALKLLRVKLVNLINNLKEFALKYKDMPALGFTHFQAAQ
                     LTTVGKRACLWTQDLILDLEDLNYRIDNMKLRGVKGTTGTQASFLSLFEGDHEKVKEL
                     DKKICKKMGYHSSYAVSGQTYTRKLDYQVISILSGIAQSMHKMTNDIRLLQSLKELEE
                     PFEKNQIGSSAMAYKRNPMRSERIASLSKYIISESISPAMVQATQWLERTLDDSANKR
                     LAIPQAFMAADAILEIGINVTDGLVVYENMINRRVNEELPFMATETILMEAVKRGGDR
                     QELHEIIREYSMKAAYRVKHEGKDNNLIELIINDDSFKMSKEEILSIMDPKNFIGRAP
                     EQVVEFVNEVVEPAIKDYKEDLGKVDVDLRV"
     gene            complement(54287..55195)
                     /locus_tag="PC465_001491"
     CDS             complement(54287..55195)
                     /locus_tag="PC465_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2648809.1"
                     /translation="MYSTKILDDYEYETFNVFSTKLNPNTKHDYLSKVILFKEFLKGK
                     ELIYATKEDCKNFVDYIQTKYAKSTCEKIYSYLHSFYNFLKKEGYIDINPFRYVEKPT
                     VTRIKTKDDVLSIQEINKLIGILPKLNIRDRVIIVCLVTTGCLLNELVSLKWKDLMVD
                     ENDNSYVRLGKGRKERVVKLHPYFFKLLEDYRNYSGLPEVIIPSDDFIFTTQKSNSIT
                     DRNVRLIVKKALDLAGLSQYSARDFRHSFAAISLRLGADESDVKNQLGWSDKYYAIRY
                     KYVLNFVDSEIVDYLIEKDNLDINKK"
     gene            55452..56276
                     /locus_tag="PC465_001492"
     CDS             55452..56276
                     /locus_tag="PC465_001492"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDF2648810.1"
                     /translation="METFSLLEIFKAVILGIVQGITEWLPVSSTGHMILVDEFIKLNF
                     SNTFISTFLVVIQFGSILAVLVIFFRKLNPFDSAKNIKQKKETVRLWLKVIIAVIPSG
                     VIGILFEDDIDRLFFNSTVVAIALIVYGIIMIGLEKRNKKPKYKDFSQVTYKLALCIG
                     LFQCLALIPGTSRSGSTIIGAVLLGTSRYVAAEFSFFLAIPTMLGASALKLLKAGFGF
                     TGFEWLILGVGSVVAFVVSIVVIKFFMDYIKKHDFKVFGYYRIVLGIVVLAYFFLL"
     gene            56316..56846
                     /gene="lepB"
                     /locus_tag="PC465_001493"
     CDS             56316..56846
                     /gene="lepB"
                     /locus_tag="PC465_001493"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDF2648811.1"
                     /translation="MSVKKEIFDWIKSIAMAIVLAFVILQFIRPSIVSGESMYPTLDD
                     KDYLILNRISYKVGKPEKGDIVVFKTNLVDGETGKKKDLIKRVIATEGDRIKISNSKV
                     YVNGKLLNEPYIHNNYTSGDIDTVVPKGKLFAMGDNRENSNDSRFPDVGMVDENEVLG
                     KVMVRLLPLDNIGKVD"
     gene            complement(56928..58709)
                     /locus_tag="PC465_001494"
     CDS             complement(56928..58709)
                     /locus_tag="PC465_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HDF2648812.1"
                     /translation="MSQYININSQLDALKLKEFEKIFYENINEDVKVVPKVTPFKGIN
                     TDLLYVKDGRILFIKFMDTTEDIFFILEEELLEVMNEEYELLKLKMGQKNRNISYNYV
                     YIMPYVEVEETYEFEEFVNNNIIDKNKLQDIMNKGSLEEYLNDENDEINLNLFLLDIC
                     SEYYIINDKLHLNEKFKKISFYNDDYKYTATMMEDVQIKDVVSIKYGNTLIEGGSGIG
                     KTAIMLSRAIKLAKVYPHHKLVIFTHTKQLCNELRERIELLYKDNNNLEVHTFSSFIF
                     KLAKKFNLIVDYNMLKNDYEKTFNNLVKQAQNIIKNKNMFKAIFIDEAESFLEYEIDF
                     IREFLYKTKFIFNVCSCNSLNISNRLNIFKKLYNGIEFDDKIILSKNYRQAKEIVDFT
                     NKFSNNSNSYINELRPNTEFSTFFYTKALRGGNKSVDIIKVSDLDDQISSVIWEIEYL
                     ISKKGLDYSEVAIVYPYNKKKLKSGKTIYFQYMLKKALEEAKIPYICAEDNLTNISKK
                     VGTTIANIYAIKNLEYKAVIVCELEMLYNQTINDIEQDYQVNDFVGDLNKVYLAMSRA
                     TDYLSIVTTFNEEASDIIRLITESKDI"
BASE COUNT        19530 a         9654 c         6742 g        22932 t
ORIGIN      
        1 acttttttta atttattatt tagattttta atagattttt taactatgga ggtatttaaa
       61 atatggaaat aaagagatat gaaggaactg gaagaatgag tagaactgta gttcataaca
      121 atacagttta tttatgtgga caaactcatg ctgaaggagg agtaattgaa caaacaactg
      181 aagttttagc taaaatagaa gatttattaa acaaatatgg ttcagataag caacatttgc
      241 tatctgttac tatttattta agagatatga aagactttga agctatgaac tctgtttggg
      301 atgcttgggt tgaaaaaggg tttgaacctg ctagagcttg tgttgaagct agacttgcta
      361 gagagcattt gttagttgaa atgagcgttg ttgcagctac aaaataatca atttagctta
      421 taggaggcta tctcaaaaca gagagataag cctctttttc attgttgaaa tgatgaaaat
      481 atatttgatt tcgtataaaa gaaagtgtct cacgaactaa aaaattcatt ttgagacacc
      541 tcctcactat ttaatctata taaatttact tattctctat tggcaatatc aatttagatg
      601 gatatttacc tccatggtaa atcgtattct ttgcttctat atattcaata ctattatatc
      661 cctctgtcgt gttgctattt tggaaaataa agtttttagc actagatgtt atatctagtc
      721 taattttatg accaacttta aacgtgtttg atatttttga agttataacc gtaaacttat
      781 aaatctctcc ttcttccata aactctgact tataaaaact atttctaaat ctagcactaa
      841 gtataccatc agctaattta attgaatttc catctaaatc cacgtccata atttttataa
      901 cccagtcagt atctttggca gaacttgatg caaaaaactc taactttata tcacctgtta
      961 cagtaaattc ttcactaaaa gcatctgatg tataacacaa catatcactt cttttttcta
     1021 aatctttgta gttatttgga actccaactt cattctctga catatcaatt agttgtactg
     1081 atgggtcttt tggattatat atataactat catacttttc ttctaaatca ttatcaaata
     1141 ctaatctacc atttcctaaa gatgtgttag catttccatc acttattaga tacatacttt
     1201 tatctatctt atttattatt ggccaatttt cttctgtctt ccacttatta gaacctacag
     1261 agtaatactc tactggagca gtcgtatcta tgttattttc tatacctttt aagtatttat
     1321 caaaccataa tagataatta taatccaaat catatcttaa tgaactattt cctaaagaaa
     1381 taccatttat atctcttaaa gtatttgaat tatgcatcca tggacctaga atagcctttc
     1441 tctttccttt ttcatagtcc tttataacat ctaaggcctc tgtagttccc atactattat
     1501 catcatacca cccagataca accaatgcag gtacatttat tttatctttt tgtaaatgcc
     1561 aatccatcaa atcccaatac tcatcttttt ctactctctt taaccattct tccagaaatt
     1621 caattctata tccaagagct tcaaaaggta tattttctat tggtcgtatg tttaaaacat
     1681 catcccaatc atctcttacc attttgcttc tatcaacttt atttcttgat accataaatg
     1741 cccatgcaag cataccagat acaaaagctc ctccttttct tggtatatca ataaaagggc
     1801 ttcctgatgt tactatacta actaaagctt taagatgctt attgcctgaa gatgcagctg
     1861 cccattggac ataaccaaga tatgatgctc caagcattcc aactattcca cttgaccatt
     1921 cctgtgatac tatccaattt atggtactat ctccatcttc cctctcatga atcaaaggtt
     1981 cccacttacc ttctgattca tttcttcccc taacatcttg tattacaaca gcatatcctc
     2041 tttgtacata tttataatat atttctttat cattttcttt tccatatgga gttctcataa
     2101 gaattgtcgg tgcttttttg gtagaatcta caaaatcagg gagatataca tctgtagaaa
     2161 gttttatacc atctttcata tcaatcatat aatttccacc aaatcttata gaatatatct
     2221 cttcattttt atgagttttt tcccattctt ttaatacagt atactcttca tatccatcca
     2281 taattaatat agtacaagtt tctctggata aacagataaa acctactatt ttattatcta
     2341 caataattat atctagtggg aactttttgt ttctttgaac ccatatatat tcattaagtt
     2401 tagaatgcgt ttctcctaag ttatttataa ctgtgtcttt atctgtgttt actaagcttt
     2461 tagtatatac atcaaagtta ttaaataaag actttaaatc tatttttgta agatttaaat
     2521 agtatgtatt ttcttctttg cttattggtt ttaaactttc tattttattt gtaaaaggat
     2581 tcaacttttc aattaataaa tctccatcaa agattacatt tccactgtat agtccagata
     2641 tgtataattt aaattttatc aattaaactc ccccctataa tcctagagac atctttattg
     2701 catatgccac tgatatacct gcataatttc ctaatactcc accaattact cccattacga
     2761 ctgctacact tacaagcgaa ttccactttg cagaagcagc tactaaagct gaagtaggac
     2821 catcagcaat tgctcctact atagaaagta ttacatattg atactttatc tttaaaagtc
     2881 tagttatgcc taaatggaaa acaaatgaag caaaaattat gctaaaacag taaagtgtta
     2941 tagtaaaagt tgaacctaaa aactctttta tatctactga aaaacctatt gtacataaaa
     3001 agaataatgc aacaaataat cctaaatcta aatttccctt tagtttcttt actggcttta
     3061 attgagcaat tataattgaa attgttgtaa ctaaaagtat tcttgctgca ctactaaaac
     3121 ttgaattgaa atatccagca agtattgttg aaacttctgt aacaacaaaa cctatagcca
     3181 acatccaagc tatatcttta atactccatt cttttgactc cataaattct tcattttgac
     3241 aatcttctaa ttctgattct tctacatgat atggccaaag ttttttaaac ttctttgaat
     3301 tttttaatat tgctggtaga gcaaacataa atatcaatgt tggtactcca attacatagt
     3361 ctgctgcatt tgctgctgca agagtttgtc tacttacatt aagacctgtt ccaatagctg
     3421 taagattagc acttccacca gtgtatgtac ctacaaacat tccagcaacc ttccaacctt
     3481 ctgatatttt ttctgcaaat actaatccaa ataaaaatgc catgatactt acagttaata
     3541 cagctacaaa aattgcaatt aaaggttctc ttgataattt tgtcatttct tttaagtcaa
     3601 cactcatcaa cattatagtc atagaaactg gaatagcata tgttgaaata gttccatata
     3661 actcagtact tactggaact acttttaagt ttgaaagtat tattcccatt atgattattg
     3721 taagtgctgg tcctaagctt ttaatggctt tgtatctttg taagtaaaaa cccaatgcaa
     3781 tcattgatgt cattacagca agtatactac ctggatttga aaaaagtgta ttcatattta
     3841 acctccaaat ttatcataag tttacttcta ttcctaaacc tggtttattg acaagattca
     3901 taatatctcc atccattaca aatcctccag atataccttc taattcttca caaaacataa
     3961 aactatcaag gtcagcttct gttatgttct ttttagatgc tattaaattt gctgctgctg
     4021 ttataccaat tctcgtttcc agcatacatc ctaacataca atttactcca cttgcctcag
     4081 ctatgttgtt gatttttata gcaggatata ttccacttga tttcatcagc ttaatattaa
     4141 atgtatcaac tgcattcttt tttatagcct taattgcatc tattggtgaa tgtaatgatt
     4201 catctatcat aatttttgtg ttacttttat ttcttatgta agcagtacca tctaaatccc
     4261 aatgtggaag tgcttgttca attgcatcaa cattaaattc ttctaacttt ttgatagtat
     4321 ttatactgct atttacgttc catccttgat ttgcatcaat tctaattctt atactctctc
     4381 caacggcttc tctaattaac tttacagctt caatatcgtc ttcaggattt atacctgctt
     4441 taagcttcaa tatcctaaaa ccttctttta ctctttctaa agcttctact gccatttttt
     4501 ctggcttatc tatacttata gtaatatccg tttggacttt actatcaaat cctccaagaa
     4561 ctttataaag gggtgcattc ataatttttc ctttaatatc atataaagct atgtcaatag
     4621 ctgcttttgc agaagtatta cctataataa ttccatccat gatggtatgt atggtttcaa
     4681 tatctagtgg gtctttgcct attaactctt ttttaaacat aagtaatact gaaagaacat
     4741 tatccaaaac ttcacctgta actgctgcaa gaggtgctgc ttcgccaaat ccacaatacc
     4801 cttcatcagt ttcaattttt aaaattacac tttctccata ttcaattact ccaaatgaaa
     4861 ctactacagg tttttttaat ttaattctaa gcttttcaaa tttgatatct gttatcttca
     4921 tattaccctc cttatttttt gaagttataa ttcaattttt aaaattttat actttaaatt
     4981 atattattac ttcaatatat atgtcaagat aatttactga aaatttactc ttttccaaaa
     5041 tataatgtga taatcttaat tcaattaata ctcttctatt aaattttttt attattattt
     5101 tctttgtatt aatttaacaa taattcattt tcatagactt ttatttggat ttaattaaat
     5161 tttaattgtc aaaatctact atgtattctt attgccacta cttctatgtt gtgctataat
     5221 tactttgttt taagcgaata ttttatatta attttattat ttggaggttc ttatgctagg
     5281 tgaaaagatg agaaatataa gaaaaagcaa gaaaaaaaca ttaagtgatg tttccaaatt
     5341 gacagattta tctataagtt atatctctca aatagaaaga gatgctattg aaccatcctt
     5401 gtcttcattg agaaaaatcg ctgaagtttt agacactcct ttatatatgt ttatggatga
     5461 caataatact gatgatttag tcattagaaa agaagataga gttatgatga aatttccaaa
     5521 gagtgaaatg ttttacgaga tagtatctcc aatgcctaca actgagttta caccttcaat
     5581 tttatttgta gagtttgaac ttaaaccaga aagtgaggat gccaaagatt atatatatca
     5641 tgcatcagaa gaaattatgg tggtaacgag tggtgtggtt gatatttgta tgggtgaaaa
     5701 ggtagttaga ttaaatccag gtgactcaac atttataaaa gctaatgtac cacataaaat
     5761 catcaatcca agtaaagata caatagctcg tggatatgga gttatatcac ctccaatttg
     5821 gccaataaaa tctaaataaa ctcaatatga cacacctact ttttgtagat aatataatag
     5881 atttaaatat tgcttttatt ttaaatttga agtatttatt taaatttaaa atatttactc
     5941 aaactaaaaa aatagctatt tgactaatct aaaccatctt aattatggta aatagtaaat
     6001 agctatttgt aagttatatt ataaattata ataaaaattg tatttgttaa aattaaatta
     6061 aactgctata tcatttaata cttttgcctt tacaactctt atatttttca tactcttgta
     6121 gatatcttga atcttatctt cttgctctct caatagtcta tgtgcttcat atatatctac
     6181 aagttcaaat tttactacat catttggctt tgcttgtgct aacttataca aatctacact
     6241 tataacgttc cctatcttag tatagccacc actagtctgt ctatctgata acattataat
     6301 cggttttcca tgaccaggta cttgtatagc tccataagaa ataccatcag atataatatc
     6361 tgctccatta aggtgcttta tactctctcc atctagtcta caacccattc tatctatttc
     6421 attcgtaact ttgtatttat ttgataaaaa tttctctact tcaccgttag aaaaagcatc
     6481 aaattgagga ccttttacaa ttcttagtac gatttctgaa ctataagttg gaatatattt
     6541 tgaacttaat tttttattta ttgtaaaatc tttttcctga ataaaagtat ttatataatc
     6601 tcctttttta agtgctctac cttcaaatcc accaatttta gctcttgtat aagttgactt
     6661 acttcccatt gcaagtggaa catctattcc accagctatt gacacatagg ctctagcacc
     6721 tgatttcaca cctctaaatg ataatacatc acctggattt atttgatatg acctccagtt
     6781 ttgaatttct tttccattta ttttagcccc taaatctccc ccagttactg ctatttgcgt
     6841 atattcatca aaggtaattg taggacctaa cattaaaact tctaaagaag cctcatcttc
     6901 agaatttcct actaatatat ttcctactct atgtgcatac tcatccattg ctccacatcc
     6961 agatacacca tattgaccat agccaactct gcctctgtct tgtattaatg tttggaaacc
     7021 tcctaattca actttgaatc ccatatatac cactccctgt actataacga tatttaaata
     7081 cttaagttat ttttttcgat ttctataaat tcatctaatg ttattggaac aaattttata
     7141 aaatctccag ctctaagcaa aatctgttct tctctatttt catcatataa ttttaaaggt
     7201 gtcctaccaa ttatttgcca tccacccgga ctatcaatag gatatacacc agtctgggaa
     7261 cctgctattc caacactccc accataaatt ttagtccttg gcacttctaa tctaggtgta
     7321 gctattcttt catccatacc acctagatat ggaaatccag gagtaaaccc tagcatatat
     7381 atcaagtact ctctacttgt gtgtattttt ataacttcat ctacagtgag attattgtag
     7441 cttgcaacgt ttttaatatc tataccaaaa acctcatcat aacatactgg aatctcatgt
     7501 attttaggtt ttggtaatac tatactttcc aaattatctt ctattttttt taaattctca
     7561 atcaaactat caaaatctat ttctaatgga ttataactta tcataagtga cctatatgtt
     7621 ggtaccattt ctgttacaat acctttaaga ttcgatattt ctattgctct cataaatgaa
     7681 attacttttt tgtttatatc ttctgatatc tcatttccaa attcagcaac cactgcctta
     7741 tcccctgata tcaagtatct agtttccata aatgtcacct cttctaagtt aagcaaataa
     7801 agcacctagg ctgctaagag aagttattcc tgtatatgca gatattaaaa ctactattaa
     7861 tccaaatatt aaaagccatg taggatgctt gtaatctcca acaatatctt ttcttttaga
     7921 tgctataagc ataattccta atgtgattgg aagtatcaat ccatttaaag ctcctgctaa
     7981 aattaataaa gtagctggtt ttcctataaa tgccattata agtgttgata ttgctataaa
     8041 tgctattata aaatattttt catatttatc tataaaagga tttagtgtct ttaagaaaga
     8101 aactgatgta taagcagctc ctataactga tgtaattgca gcagaccata atacaagtcc
     8161 aaagaattta tatcctattg ctcctgcact aaatttaaaa gctgaagcag ctggattttc
     8221 tgggtcaagt tgaagacctt ttgaaaccac tgccagtatt gctaaaaata aaagaactct
     8281 catcattgtg gcaactaata tacccaaaag agaagattta gttatttctt ttatattttc
     8341 ttctcctgtt attccaccgt ctattaatct atgtcctcca gcaaaagtta tataacctcc
     8401 aacacttcct ccaagtagag ttattattgg gaatatcagt ccttttggat tttctggttt
     8461 taccattctt gatactgcct ctccaacagg aggatgattt gatattgcta catatccaac
     8521 tataattatc attcctaatg ctaaaaattt agttatctta tcgactagag aatttgaatt
     8581 ttttgacata aatacaaata tggctattaa tccacttaat acagttccta atgtcatatt
     8641 catattaaac attacattca taccaagtgc agctccacca acatttccta tattaaaagc
     8701 taatcctcca agagctacta aaaaagctac taaataacct aatcctggta ttattttatt
     8761 tgctatatcc tgacctctaa gtcctgatac accaattact ctccatacat ttacttgagc
     8821 ccctataaaa aggattgttg taattaaaat tacaaatgaa aaattcggtc caaaatcttg
     8881 ggtaaattgt gcagtctgag ttaaaaaccc tggtccaatt gctgatgttg ccattataaa
     8941 tgcagcccct ataagtgctc caacatcttt tttattttta gttttatctg taatattttt
     9001 tgtactcata ttttatctcc ccctcatgtt atcagtctta tactatgttc tctgacgaac
     9061 aaacttctat gttttctaat ggacaaactt ctatactttc taattcaaaa cgctttctta
     9121 tttctttgac aaactctatt gcttttggat tgtccccatg tacacatata gaatctgctt
     9181 tgatatgtat aacttcacct gttaaagttt ctacagttcc ttcttttacc atcctaacaa
     9241 ccctatctat tgcatgtttt gtatcatgta taactgctcc ttctacactt cttggaacca
     9301 aaaaaccatt attatcataa gctctatctg caaatacttc atttgcaaac ctaagtccaa
     9361 tttctttagc agaatttatc atttcactat tatatagccc caacagtata atatctttat
     9421 cgacttcata tatagcttca caaatcccca tagctaactc tttatcttta gctgccatat
     9481 tgtataatgc tccatgtggt tttacatgtt gtatattaca tccatttgaa cttgcaaatg
     9541 ccattaaagc acccaattga tattttgtat aatctttagc ttcctgcttt gttattttca
     9601 tctcacgtct tccaaatcct attaaatcta ggaaacctgg atgtgcgcct attttcactc
     9661 catttttttt agctagctgt actgtttttt ccatatgact agggtcacct gcatgaaacc
     9721 cacaagctat attggctgat gaaatatatt ttaaaacttc ttcatctaaa ccaatcttat
     9781 acgttccaaa actttctcct aaatcactat ttaaatctac tttatacaat ttatgacccc
     9841 tcctcgctaa cattttgata gaataagtag ttttaatttt taaattttgt ttattttata
     9901 tattgcatga aatattttat cacttgtatt caattttatt tttgcaacta ttctattgca
     9961 tttaattaat ataattttac catttaagga atatttttgc aattatttta attgaacatt
    10021 catttgtatt tctttttcaa aaaatctttt taccattttt tagttaataa ttaattattt
    10081 tcacttaaaa taagggcctt aaccttcatt tttaaagtat ttttcatttt taatcacttt
    10141 atatgcaaga cagaatcatt tttcttcatt catttgtttc tttcatctat ataattatca
    10201 ttctttgtaa gtaaaatatc tttatatttt tataattaat tctttatata gttttaagta
    10261 taataaaatc atgtatacta aatgcatgtt aaaatattat tttaaaacat gcacaatatt
    10321 tgtacatatt gtagacatat aaacctataa attatacaat agtattgtta agattatata
    10381 tttttttaac ataaattttg tattggggga aaaacaatgg ataaaaacta tacgatgcca
    10441 atataccaaa aaatagcgtt ggatattgca aataaaatat acacgggtga aatacaagag
    10501 gattcagtac tatttggacg ctctgttttg gctggtaaat acaatgtatc tccagaaacg
    10561 ataagaagag ctgtcaaaat tttagaggac attggcgttg ttaaaagcat aaagggtaaa
    10621 ggtgttattg tactatctcc agacaaagct tcttctttta taaaaaaata tagagatatt
    10681 acaaatatat catcatataa atcaacactt tataatttaa tagatactaa atctaattta
    10741 gaaaatgaaa tattagatac tataaataaa attttagact attctaacag acttgaaata
    10801 atcaatcctt tagtgcccgt tcagttcacc ataaattcta attgcaaata tattggtcaa
    10861 acagctgcac aaactaaatt ttggcaaaat acaggtgcta caatagttgc aattaaaaga
    10921 ggtgaagaac ttataatatc tcctggacca tatattgaat ttttagaagg agacattctc
    10981 ttagtagttg gtgaccaaca catttacaat tctataccaa tgtttttata tgaaaacgaa
    11041 aaataaatta tataatttag tgtgattata taaaaatgca agattaacaa caaaaaaaga
    11101 gcttcatatt ttacataaag ctctttttaa attcaaataa atttaacttt gattaatttt
    11161 taaatatcca attcatcttc tttttcccag cttaaagctc tcgatacagc ttttttccat
    11221 cctttatata atttacatct cttctcttca ctcatatttg gattaaactc tttttctact
    11281 gaccactttg aagtaatttc atttcttcca atatagaatc caacagacaa ccctgctaaa
    11341 taagcagctc ctaaagctgt agtttctact attttgggtc tatctatatc tacatttaat
    11401 atatctgatt gaaattgcat taaaaaatta ttattacttg ctccaccatc aacttttaat
    11461 gattttagtt ttaattttga atcgttttgc attgcttcta aaacatcctt tgtctgataa
    11521 gcaattgatt ccaatgtggc tcttactata tgttcttttt ttgctcctct tgtaagtcct
    11581 aaaattgaac ccctagcata catatcccaa tatggagctc caagacctgt aaatgctggc
    11641 actacatata caccattagt atcctctacc ctatttgcat acatttcact atcttttgca
    11701 gattcaatta tctttaattc atctctaagc cattgaacag atgctcctcc aataaatata
    11761 cttccttcta atgcatatgt tacttttcca tcaactcccc aagcaattgt tgtaagtaac
    11821 ccatgcttag atttaactat gttactgcct gtattcataa gcaagaaaca acccgttcca
    11881 taagtatttt ttgcagtacc ttcttcaaca caattttgac caaataatgc tgcttgttgg
    11941 tctccagcac atcccgcaat aggtatttta gctcctgata acatgcgctc atctgtatga
    12001 ccataaacat agctagaagg ttttactaat ggcaacatgc ttattggtat gtccaattct
    12061 cgtaatatat cctcatccca ttctaaatca tttatattgt acatcattgt tctagatgca
    12121 tttgagtaat ctgttacatg tacttttcca cgagttaaat tccatattaa ccatgtatct
    12181 atagttccaa ataataactc tccttgttct gctttttccc tagctccttc tacattatct
    12241 aatatccatt ttacttttgt tgctgaaaag tatgcatcta ttaaaagacc tgttttttct
    12301 tttattgatt cttccaatcc tttattttta agttcatcac atatttctga cgttctccta
    12361 cactgccata ctattgcgtt ataaataggt ttaccagtat acctactcca aacaaccgta
    12421 gtctctcttt gattagttat ccctattgaa gcaatttctt ctggtcttat acctgctgtt
    12481 tctataactt ctctcattac cccactttgt gacccccata tttccatagg atcatgctct
    12541 acccatccag cttttggata aatttgattg aactcttttt gtgcaatttt cactatttcg
    12601 ccttttttat taaatagtat agctcttgaa ctggttgttc cttggtctaa tgccattaca
    12661 tacttctttt ccatcaccat attctcctta tcatataata tttaatttat taaaaagaaa
    12721 aatttaatat cacatatttc aataaataat catacttaag tacaaattta atataataga
    12781 tatttagtaa gaagacactt attttctatc atatctatat aataatatta tacattatag
    12841 cttacatatt gattaataaa ttttaaagga gtataataaa cagtgttcat aataatttta
    12901 ataaaagagg tggtaatatg ccaaagattt tagaaaatgt aaaagaagat atattaaaag
    12961 tgtctcggga tatgatttta gaagaagatt actcgtatat tagcataagg aaaatagctc
    13021 aaaggtgtgg tataagtgca ggtacagtgt ataattactt taattcaaaa caagaaataa
    13081 tagaatatat cacaaaatct gaatgggatt tattgataag gcgaattgaa tactccaata
    13141 aaaacactga agattacata aaaaaactaa acattatttt tactgaaata agaaatttta
    13201 taaacaaagt tcataatatc caatacaatg actttttaaa cacttttgaa acagagagat
    13261 tttttgaaat gaaaaaacac aaagacgact ttcatgaaca gctttcaaat aaagtatatg
    13321 aagctttaga aaaagaaagt ttttttaata atgacaaatt agtatgcaat atcataataa
    13381 aaatgttttt ttcatattca acatatcttc atatagaatt tgaagattta aaaccctata
    13441 ttgaaaaatt aatacattaa ggtggtgttt accttgaatc ataatactag tattaagaac
    13501 aaggacagta atccaaaaat atttttagta cttacacttt atctattagg tatatttatg
    13561 ggagctattg atactggaat agtatcacca gcaagaacga ttatacaaaa tagccttgga
    13621 gtaaatgaaa aaacgggaat ttggatgatt accatataca cattaacata cgcttctgta
    13681 attcctatct ctggaaaatt agcagataaa ataggaagaa aatatgtgta tctagttagt
    13741 atatttctat ttggtagtgg ttcattaata tgtggattat catcactatt ttccaatttc
    13801 tatattttat taattggtcg tgttattcaa gcaattggtg gtggtggaat catgccaatt
    13861 gctacagcag aatttggaac taccttccca gaaaataaaa gaggcatggc tttaggttta
    13921 gttggggcaa catatggtat tgccaatatt ttaggttcaa gcattggtag cacaattcta
    13981 agtatctttg gaactcaaaa ttggaagtgg ctattttttg taaatcttcc aatttgttta
    14041 atcatactta ttggtggagt tttctgtatt aaaaacaata agtctgaatc taaagaaaaa
    14101 atagataagc ttggtacatt gatgttgata tgtataatcg tatcactatt atatggtctt
    14161 atgaatatag acttttttaa ttttaaaaat tctatacaag atatatcagt ttatccatac
    14221 ttattgacat ttattgtact tatacctatt ttcatattta ttgaaaatag agctaaagac
    14281 cctattttaa gctttgaata ttttttaaat ccgagaatat tgatagtact tattttatct
    14341 ttaattgttg gtattggaat gatgggtatg gtattcgttc cacagtatgc tgaaaatgca
    14401 ttaaagataa atgctggttc tgggggatat tttgtagcta tattgggatt atttgcaggt
    14461 attgctgctc ctttaagcgg aagacttatt gacaaatttg gggcaaaaaa aatactatta
    14521 ctaggatttt ctgtatctat gataggttct ctttacctag ttttaattgc tctaaaaacc
    14581 aatactgtat ttagtgtatg tgtaagttta atatttatgg gattaggaat gggatttact
    14641 atgggaactc ctctaaacta tatgatgtta tcaaatacaa gattagaaga atctaattca
    14701 gcacttgcaa cattatcctt gatacgctca attggtactt caatttctcc agctataatg
    14761 attggattta tagcacatgc aggattatct gtgcaagata atattatgga cttagttgga
    14821 aagccctcaa ctcctaaaat agttcaactt gaagaacttg aaaacatgat agatgactta
    14881 aaatcagacc ctgaaatggc aaaaaattta aaaaatgtct ctatcccaaa tatgaatgat
    14941 acttcaaata taaatatgga catgacaggt ggcaaacttc caaaatcctt acttaataaa
    15001 gttcagtcag cagatacaac caacattacc aatataacaa aagaaatatc aacaacaatg
    15061 tttgatgaaa aagttccatc tataattact aaaatacaga aaaatgtaca aaaaggaata
    15121 gatggaacac aaagtggaat aaacggtatt gaagatggtg aaaataaact aaatagtggt
    15181 attaaaggag ttcaaactgg tattgacaat atggtaaaag ctagagctgg tattaatcaa
    15241 ggaatagatg gtgtaaaaaa aggtattgct ggtgttgaca aaggtataaa aggtatggaa
    15301 caaggtcttg aaaaacaaga tgaggccatc aaggaactta caactgctta taataaaata
    15361 cctactacag aaaaaactcc tactgataac gaaaataact caaatgaaca aaaccagagt
    15421 aataccagta attctgaatc agatgacact aagaatgatt ctacagaaaa taagaataac
    15481 aattccagcg agaataaacc aaatgtaaat gaacaaaaag aaagtttaaa tgctcaaata
    15541 cagcaactaa aaaagacaag agatgactta aatacaaagt tacaaaaaaa taaaactcaa
    15601 aagaacgaat taagtaaaaa actaagatca atggaatctc aaaagaaaga gctacaaagc
    15661 aagttaaata attctataag ccaaaagaaa gacatggaaa aaagccttga tacaatgcaa
    15721 cagcaaaaaa aatcactcca agcagtttta gcaaagacac aagaggtaaa aactgaaata
    15781 ccaaaggctt ttgataaatc aaaattggat tatataaatt ccatagaaaa taatagaaca
    15841 aaaatagaaa atacactaca atctactcta aactcaggat ttaaacagat gtatataaca
    15901 gtattctgtg taaatctact agcatttata atattattgt tctataaaga aaataaaact
    15961 agataaaaga gtgttatagt attatattgt aaatttatct tattcttaaa tattttattc
    16021 taaagaataa attcataaaa tttttgtaat tgattaatat aaattacaat ataatactat
    16081 ttttctctta atctttttct cttttacaga caatcaaaaa gcaatcttag tttatcgaaa
    16141 taaatttata caatctattc atacacccct ttacattttt ataacaatta aacctattgt
    16201 tatatataca aatcaaaata aaccatatat tttcaactat aatatgttaa aatcatatta
    16261 tgagcatatt aatttaagca aaatgtcatt tagactttaa tttagtagtt ttatattata
    16321 aatttatata tttttaattt taaatgtcat ttagacatta ctcataaaaa gaaaggagtg
    16381 tattttgtgg atactttagg aaaaagaatt gcttatttga gaaactccaa aaaacttact
    16441 cagcgcaaac ttatggatat tttaaaattt gaaaacttag gcaagtatga aacaggagat
    16501 agaaaaccta attgtgatat actaatgtca atagctgatt attttaatgt tacgactgac
    16561 tggcttctct atggtaaaga gaaggtaaat gtcaatagta gtgtaaaaga agataaagaa
    16621 gattacttac atgttactaa tgatgaaatg atgatattaa atctatacag acaactaaac
    16681 gaacgtgata aaataaaaat agaaggaata cttgaactta agatatctga atataaagac
    16741 ttaaaaaagc attcctctaa taataatgaa gataaaatgg tttaaacata cataatttga
    16801 tacgatttta catcatctat taaccttctt tttttgtagt atattactaa aatatggata
    16861 ttggattatt taaaaacaag tatagtctaa tttcaagcac atttataata tttagattat
    16921 cttatccata ttttagttta agtactttga aaaatataat acatctctat gtataactta
    16981 gattcctaag aaatgcatta ctcatgtttt taattcttcc aacatctttc tatacacaat
    17041 tgtacatcct tcataattcc cctctttaag aaggattgaa catgtactag aatatttagt
    17101 taaagtattt aatctttcca tatttaagct ttttatatta ctgagtgctg taataaaatc
    17161 atcaattgct ctacaacact ctataacccc atctgaatcc aatttacaca caagaatatt
    17221 cacctacttt atatactatt tattaatcat cttctgaata ttctatatta agtaattgat
    17281 aaattgatga tttatatttt ttacctgttc ttcttccatt taaaatagct gacaaatagt
    17341 tttcattaac acctattttc ttcgctaatt ccctttgagt catatttaat tcaataagtc
    17401 tttgcttgac ttgcactccc aaaaaaggta tccatttttt tcgagcatcc atttatcaac
    17461 ttcctttcta agtgatttat atttactttt atattatttt agcttacaca ccccctctat
    17521 ttagtatata tttttaatat gtacacatat taagtatata aatttattta atactaaata
    17581 agattttttg attactttgt gctaaaatta ggatgtaaat tcgtatcatt aagttaatta
    17641 taaagtcatt ttgaccttaa gtcaatggtt tttatgtcat tttgaccttt aatttgaaac
    17701 tatttacatc ttaaaaagtc tttttgacat taattgaatg gagagtgttt atggatactt
    17761 taggagaaag aattgtttat ttgagaaaag caaaaaacct taaacaatat gaactagaag
    17821 aaatgttggg ctgtgacaac ttaagtaaat ttgagagaaa cattagaaaa ccaaattatg
    17881 aaatattaaa atctatagct gagatattta atgtttcagt agactggcta ttaaatggag
    17941 ataatctatc acataaatca gatttaattt gcgattcctc ctcaaactat ccacttaata
    18001 gcataaactc taatgaaata aaacttttaa acaactttag aaagttaaat gattatgata
    18061 aagccaaaat agaaggtatg attgaattaa aacttcatga atatgaaaaa gagaaggatt
    18121 taggaaaaat tgagtataac aaaaataaag atgagaaaat agataaataa tttttatgtt
    18181 gcttttgata cgattttaca tcatttcttt gttctaatat ttttatttca tttattttct
    18241 tttttataat tttatgataa aataattagt atattttgct ttacttgaat gtaattattt
    18301 atacaaaagt caaacataat ataaatgtag taaattttta gtttcaagta atatctcgtt
    18361 attataacta aatatttatt aaaattagga ggataaaatg ggcttaagag acaaattcgc
    18421 gcaatcattt gctagatcaa aaactatgag tggccctgag aaaaaggcta atgaaataat
    18481 gggtaaattg cttcttaaga aagctatatt acctatcgtt ttaatgttcg tgataataat
    18541 cgctggagct atgcttaaaa tcaattcttg ggttacactt ggcataaatt tagttattgc
    18601 tgttggtgct ttcttctaca taagaaattc tagtaaaaag tatcagaact ttaaacctta
    18661 tgttggcaat ttgattagtt tagagaaaaa aggtaaaaaa gagtacgttg ctattataaa
    18721 acaaggtaag ttaccagtta agttacaaat agcttatggt ggtgaagacc ttgaacatgt
    18781 taagaaaaat caaatggttc aaataagtta taatccagat gctaaaatag ctattttggt
    18841 taatagacaa taatttaata aaaaaaaaga gttgtcttaa aattgatttt tcacaatcaa
    18901 gtttaagctc aactcctttt ttaattttta tatgttattt ttattacttt tttattaata
    18961 tctctaagtt ataaaattcc agtctataca atattccatt ttttattttt atattggtaa
    19021 catatctttt atatcattaa tcaaactaat tctagcagta tttacactag tacataactc
    19081 atctatagct ccttgaacat ttgtagcagc aagtttactt actgtattat cataacttgt
    19141 tttctctgct gttgtttcta tgctatcaag accttctttt acctcattga ctgcatttac
    19201 aagacttgtt ttatcagttg tattgagtag agttgtatct cctattttac tagtgacatc
    19261 tgtcttagta ttatctattt tagtatttaa ctctatttta gtagtttcta taccacttgt
    19321 taatgttatt ttagttgtat ctattttttt atctaactct tgtatatctt ttaaagttgc
    19381 caagatgaca gttgggtcaa cttttaaatt tacacttgaa gtattagaaa ctaccaatat
    19441 aattcttata attaaatctt ttacacttcc agaatcagca gttggtttat aagtttctgg
    19501 atatttagat atagctataa gcttattttc tgaatcaaat ataccaactt ctcttatcat
    19561 aaaaccgcca atactacctg gtattacagt ttctataact atccagttag agttgtcatc
    19621 atctattttt acattactta tattgccttc ccagacaact tctttaagag atgtttgttc
    19681 ttctgtagga ctatactcac ttcctccacc atctccaagt tgtagtttaa ctaaatctac
    19741 ttttttacca agagcagttg catttgcaat agatgcttta cctgctttag ttaaaagtgt
    19801 atagtatttt tgttctgcca atttatatcg cctcctgttt aggatataag attacttttt
    19861 ccatacttct atcatttcct gtagaaatgg ttatctctcc aaatatctct atatttgatg
    19921 gtgtccacgg atatacagta acagtttctc ctgtatttat agcagttcca caaaatagtt
    19981 catttttatt taacaaaatc attttaaatt tatgttccag atgacatggc tttacatttt
    20041 ctaatacttt atccaactct acaatagaat tataactaca attattaact ataaactcta
    20101 atataaatat aaattcattg ctgagtactg ttacttcaac atcagtcttt gtataagctt
    20161 cacaaatgtt ttttataacc ttcaatttag ttgttcctaa acttctcatt ttagccttta
    20221 tattgcttct tctagtctca taatttaaat cttcattatt ttgaatacac aatatacttt
    20281 cccacatatc aagaccccat gtggatgtat tgacaaacat ttgatttata gtatcatcta
    20341 tattttcttt taatgaagat aattcactat cataagaatc ttgtattgct tcaaccatat
    20401 aatttttata aaatgatggt agtttatcaa ttaatttcat taaacctcca cctcactaaa
    20461 atctaaagtt gtaacactag gtattttatc atcttcaata gttatattgt ctgttgagtt
    20521 attgacaagt aaattgctta aatcatggac tccagaagta cttattagaa tccccatgat
    20581 tttcgtgtat acaatttctc ctgttatact tctaaaatat tgatttatat tttctataaa
    20641 actatttttt accatatcta aggtatatcc actttctagc tccatagatg cacttatagt
    20701 tatatttagt gggattggag tagttactgt tagtgtagct cctattggca tttcttcctc
    20761 aatatgttct ctacacttag ttattatttc ttcttcaacc gcttgattat tttgtccaaa
    20821 caataaaacc ttaactgtcc ctgctccatt ccatcttgga tatacttttg cattatatac
    20881 accatcaact tctaaagccc attcttcata atgtgcttta ttcccacttg ttgcttgatt
    20941 tttttgtact ctaaaaaacc tttctctcag ttcttcatca gtttcaattt ctgtaccacc
    21001 tgaaaattta tttatatttg ttatcttttc aattccaaat atattatcat ttaccttaaa
    21061 ttcacaatca gatggtaaat tatatctagt tccaatttct agtgcttcga ctggacttat
    21121 atttccttct tcaccaccaa tgacaatatc ctttattacc acaaatgata aatctttata
    21181 ggatataatt gttccatttg atatttcaac accattttca cctataaatt ctacttctcc
    21241 agtagcctca gtacccaatt ttctatatac accaaattca ttcactctct tatctaataa
    21301 ttgattataa gtgtcttcaa taaaagccat tttatatatg ttagaaagtt caacatacat
    21361 ttttgaaagt tcaaaggtat ttccagaaac catatcattt agaaaagaac cttctccttt
    21421 atacacatct aaatttatat ttttaagggt tctatttttt attgtttcat aagtttgatt
    21481 actatacatt tatttccacc tccccataga tagtggatat ttttatatat gcacctaata
    21541 tatctttttt aaaattagta tttactacat ctacttgtaa aatatatgga ttcataagca
    21601 aagcttcttt tatatatcga gatgcttcac tttctgtaag acctttacta tatttttgac
    21661 ctattaaatc agtcaactct gttccataat catttgagta aatctcatgt tcatttttat
    21721 ttgtttttat acacttatat acccaaactt ttatagcttc atttttttca ataatcttaa
    21781 aatctccatt ttctactatt ggttcatctt tttcaaagtt ccatgctact tcacgaaata
    21841 accctaattc ctctttttta ggaatttcat agtcctctgg aacacctata aaaggaaata
    21901 ttgtgttaga cattataaac tcaccaactt acttattatt gcaaattttt ctcctacttt
    21961 aaacataata actgtgtcac ctttatctag ttgattagtg agagattcat ttaattcatg
    22021 agtatggtta ttagactgtg ttattataaa gctttttgtt gctctatcaa acaaccaatt
    22081 atctataagt aaattgtctt tatctaaaac tatattattc attgatactt ttaaatctgg
    22141 caatttattt attatttttc caacaaaaaa ggaaggctta ttataatatt tcccttcctt
    22201 ccttattatt cctataaatt catttattga attagccact ataccacctc tcttataaaa
    22261 atcttcttgc tcctacataa ttcttagaat aatagcttcc ttttagacta gatattttaa
    22321 ccacatcacc agtatgtgga gaatgtataa attcattgtt cccaattaat ataccaacat
    22381 gatctatagt tcctttaggt ccttttgagg aaaagaaaac taaatctcct ggttgcaaac
    22441 ttttcttttc tacttgcttt cctacacttc cttgtgctct ggatactcta ggaatattaa
    22501 ttcctatttt tttataacac cactgagtaa acccactgca atcaaaagta tttggtccac
    22561 ttgctcccca cacatattta catccttttt tacccttagc tatgctaatt aattctttta
    22621 cctttcctgt ggaatttgta tatcctgttc catctccaat aattatagta ccttttcttc
    22681 ttccaaaatt ataacattct tttttactag acattaatat atctatttta taaataccat
    22741 taactacctt aatagctcct cccctatctg ttactgtata tgtttttcca tctatatttg
    22801 taccagtgcc ttttacttgt atttgtgttt taaacttaag cacttcagga gcagcacaag
    22861 tattgttaga tggtacaagc tttttgccat ccatcttttg atataagcca ccttccattg
    22921 gatcatttga tggataatat gctgtaaatt ctgcttttac ttctcttcca tttaatgctc
    22981 cattaccact taaatctgaa atttcttctt tttgttcatc ttgccctaca gatttttcat
    23041 ccattatatt ttgaaaattg agttctaatt caatctgata atctccattt tgccatgtat
    23101 gtttatctgt atctatatag aataatccta ccaattttgt atacgaatct tttaccttta
    23161 cacctctacc agttatacaa cttgtatctc catatccttt tagagaacac gttctttcaa
    23221 ttcctttaaa ctcgttttct atgtctgttg tactattttc ctgttgttgt atgactttct
    23281 gcattatcac atttacttct ttaaataaag aattattaac tttctcacta attttatttc
    23341 catattggtc aactaataat actttattct ttacattttc catactttca gaaaaagtcg
    23401 tattgataag attaaatcct tcttcaaaga tgatatttaa tgtaacagtt cctttctcaa
    23461 taatattaaa tttatcaaga ttagcctcta tcatatactt tttctttgta gttttgcttg
    23521 cttctgtgta agcactcatt atagtatcat atccgtttac agatataaac attttagtat
    23581 attttacatt agtctttggt atgtttccaa ttgcaagttt gttatctgca aatacttgct
    23641 ttgcaatatc ctctactaac ttatccttaa aattatagga cacttcactt tgtaaaagta
    23701 aaaatcccat atccttggct gtaaaattaa tattaacact gcttgaatct ttagatctgt
    23761 taattatcat ccctctaaaa agttcttttt catctacata aaagcaaact gtgcttgcta
    23821 ttggaatatc aatttgttga aaattaatat cagaagctga ctgtactata gaaaattcta
    23881 atgttcttga aggagactta taatctccag accaagaaac tgaatctact atattactta
    23941 tatcatagat atttccgttt tttatgtgta cccaaatctt tataataaaa aatcacctac
    24001 ctttttctct gattttgagt aattttttat aaattgtact actttttagg gtttgccctt
    24061 agtatttgaa gtctcttata ttctcttaaa tctagtgaaa agtacacatc tcttgtacca
    24121 tctctttctt cataactaaa accttctatt atcacttcca tatttatatt tgtttctgta
    24181 actgtaaatc tcaatattaa accttcattc atccatcttt gaattttatt tacacaatca
    24241 taaggggatg gaaatccttt ataattacaa aaagaatatt ctttatttgg gaaaaaacta
    24301 gatatattaa tacttttaag agctacgcct ccaaaagttg ctatttctcc aactttaagt
    24361 atatttgatg aatttatagt tgattttcca tttatactta ttgatggtgg tataactgga
    24421 aatctaaatc tatcttcagc ttgtctaagc cacatttcca ttataagaca ccccctaact
    24481 gtgccacttg gatacttgca actaattttg atgttatctt ttctatatca gcttcttctc
    24541 taatcactat tgtatcagct aacttagcta tgtttatatt tccaccattt tttctgcttc
    24601 tatattgatt tgcttcttgt ttagttaaaa ccatttcacc ttcatgaagt ctggtttgat
    24661 agtcattata aggaacatag ttcaatccaa atgcattatt acctttctta cttgaataag
    24721 ctttaccaga atcaccagcc tttgttccag catatggatt atctttgtaa ttttttttac
    24781 tcttttccac tagatttaaa actgttcctg tgatgcttcc attttttatc ttattaatca
    24841 tagtttgcca ccatttgcat atatctttaa ctattttaca tactttatct aatatgttaa
    24901 aaaaagctcc caatattggc tctataattt tccatccagt ttccaacaga ggtcctaagg
    24961 tctcccatac agttttccaa ataacaccca gtgtctctat aaaattgttt atttgaggtg
    25021 cgtattctcc caaaaaggta aaaattctca taataattgg actaacagct tctacaacag
    25081 gtccaatcag ttgaaaaact gttgttacta cagtcccaaa tatacttatt ataccttgtg
    25141 ctactggtga tttgttattt atactatcta ataatacatt aactagattt actacaggaa
    25201 gtaatgaatt tgttaatgca gtaaaatcaa tattttgaac aagcatctga cttgtattac
    25261 ctattgattg tggtacatgt cctaatgctg tagctacctg agtttcaatt ggattttgtt
    25321 tattttcagc aatttttttc ccattcatta catctgcaac tttttgagaa aaaccaccta
    25381 ttccgcttgg cactttttcc aaaaatgaat ttattttttt taatccacct tctaatatgc
    25441 tgtcaaaagg ttcaatcata ctgtttaacc ccatatcaat atacgtggat gcactagata
    25501 ataagcctgg aatggtacca gccatttcat tagctaatcc attttgcttc tcttttatcc
    25561 cctcaagtgc atcatcaagt gttttataat tttctccaac taaagtatta agagcatcca
    25621 tattaccttt tgatgcactt acaaaagctg ctgatacatc ttgatcacta ctagtttcca
    25681 tatttaaagc tctgacattt accatagcct gagttatatc tttcgattta tcaatcttac
    25741 ctccactaat cgtcattgcc ttagtactca ttgaaataac ttcactagga tcaaaagggc
    25801 tttttagtgc tatatctttt attacatcat tataataatt attagcttca gatttagctt
    25861 caatcttatc cttaactcct gtagttcttt gaacaacatt agttaaaaca gctttttgat
    25921 tttgaccttt tcctactaaa tctacacctt tttttacagc tcctcctatt gaaaatccat
    25981 tagtaatatc agatatttta tcttttattc ctcctagtat actactagct ttatctttta
    26041 ttgaaatagc tccagtccac attcttccag caaattgttt taattttgat agtgttccta
    26101 ttaaaacatt tttagctaaa tctttaactg aaatagaact aatccattta ctatttttaa
    26161 ttttatttaa tatatttaaa gtgttttgaa caatattatt tcctttaaca cccattacta
    26221 aattgctatt aaaaacttta tttttaagtt caggtaattt accagtaact atttttttag
    26281 aagtatctac tgtctgagtt ttaactcgct taacaatatc ttgtacagtt tttatttttt
    26341 caggtttatc gcttttatta tttttagatt cattattttt tgcttttaca tttttatgtg
    26401 tatctcttcc ttttttacta tttgctactt gtgataatct aactaactta cttctagcat
    26461 tttctgcact tcttccaaga gtttctaagc cttcactaaa atctttattt gatgaacctg
    26521 aattattcat acttccattc attttttcta tagaattact taaacttttt atactactag
    26581 tcattttttt tattgaagaa tttatactat ttatactact acttgcacta gccatagaac
    26641 tcttaatact attagccatt gtatttactg aaggagaaac agatacagta actcttttaa
    26701 gggcttccgt tactgatata atttgattca tctttggagt gtaattatct gtaatataca
    26761 tatttatacc ttcttctctt acatttccca ctatatacca cctcctgtca aaggacaaac
    26821 tccatatcca tgcttcattt tttcaacttc ttcttcaatt tctaaggcga aaaaagcttc
    26881 aataagcttt aattcgcctt tatccattgt ataaaaaagg gacggtctta tacctttttt
    26941 cttccaataa tagtacatta tcgtagtctt ggtatccgtc cctattagtt ttttacctct
    27001 tctattactg catttttacc ataacccatc acatcttgaa ggattctata taagttagta
    27061 atttcacctg gtaataatag ttttcttgcc aattcttttg gtgttggagc cttaaattta
    27121 tccattagct ccttattttt aaataaaagc tttccatcca aatcacaaac accttctata
    27181 attgtaagca tctgcatctc tggtaagtct atatccgttt tcatattttc atcaatttta
    27241 agacaagtat tttgtatctc ttcatcttta cttattgtta aagctctaca cattacttta
    27301 aattcctgcc caaatatagt tgataatctc ttaagttcaa ctatagtact tggtctttct
    27361 aagttttctg tatctgcatt taaaagtaaa tctactatgt ttatattttt tgataatcca
    27421 ttttcattca ttattatttg ctcctttatc aatcaaattc aatcaactaa cttttttact
    27481 tattaactac ctgaatttat taagtatata tctactaaat atcagtataa aaccaaatat
    27541 aaaactaaat tatgtcaaga aaatcatact cagtaaatgt gaaaggagct tctatctctc
    27601 cctttactcc aacctcccaa tcagctaaag ttaaatcatc aaatgctata ttttttactg
    27661 ctattctttc tgctccataa gaatctgggt catttaattt agatatagca acaaatctag
    27721 gttcagaacc tctctttatc ttttctccaa ttaacttgtg cattcttgaa ctaacatggt
    27781 atagagttat tgaacctttt cctttatatc ccatatactt tgtatcagta cccatttgac
    27841 ctgctattat aatatcctct tttgtaaatt ccatctttgc ttgaaacttc tttacttctg
    27901 ctactttatc tccatcaagc caaagttctc cccaagtacc actcattaca tttctagctt
    27961 ccatatttgc catattaata atcctcctat atctctattg ataaatctat atcttccata
    28021 gcatctaaca tctttatttt tgcttttaag aatacttttg aacctgtatt tgcttctctt
    28081 atttcttgtt ctttcatatt agatatatct atatttttag atttcaaata ctgtttttgg
    28141 gcttctatgt ctatatctac aagtgaacca acttctatta attcttcctt ttctaattct
    28201 tctaagtatt cctttattgc cactattagt atgcatttat tatcataact attaggaact
    28261 ctacctatat agtcatctat tattactttc ttaatgtcat tatttataat atctaaagtg
    28321 tcaactattt ttattttctg gaacatttct cctttttctg ctgttaattc agttaaagaa
    28381 tttactcctc tagcaattct tatagctcct gcttctttaa taagtataag ctctccttta
    28441 ttaacctttg attctgcatc aactttcgtc atcttaggta tatcgactac atcactaagt
    28501 ttagtataag ttactgattg acttaaaggt gtacctgcta taagtccagc caccctactt
    28561 gtaaactcat caacactgta tttcttttct ccaactaaca catcttctgt agtaaaatta
    28621 attatccctt catgatttcc tacaactttt cctaatacag ctttaacctt aaccttatct
    28681 atatctctaa gtttaattat ccaatttttt atagcagtct tatcagcttc tactgctttt
    28741 ggcatacata gataattaaa ttccttagtc tctaaaaaat ctaatgcagt ttgaatatct
    28801 gcttctcctt ctattacata aactaataat ttatttggag tgttaacatt tcccatcaag
    28861 gctaaattta tatattcttt attttcagca gataaatcaa ctggtatatc ctctttttca
    28921 tgtatttcat taagacctag tgccttagca tctttaagca ccattgcaat tattcctcta
    28981 gctgaacgtt ctttaacagt tgtagctagc tccttaaatg atatgttgat acttggtaat
    29041 cctatagcca tactatcact ctcctaaatt taaattgatt tcttccatat tttcatatac
    29101 tacatcttct tcatatacac tatccagata gtttagtgta agtgtaaagt tcaatacata
    29161 aattgactct tcttttttaa tactttgttc tagctttgtt atatttaatt ttctgtctgt
    29221 tacctttata tttctgttaa atagcttatt taattcatct gaaacttcat acattctaat
    29281 actctttgac tgtggttttg gtaagtattt tatagagata acaatatctt tgttattcgt
    29341 atttaacatt acaggtgtac aaataactga tagtatactt acaaaaaaac aagacccttc
    29401 agagccttgc acactttcat catcaataaa aatactttca gtaaagtttt ttttgagaat
    29461 ctcaataatt gtttctaata tttccttgta tttaagcaaa taatcaccac actatcacta
    29521 aatattcttg cttaatctga taatcttact ataaatgata taagtcattt ttaaatatat
    29581 atctcattta ttcctgtcaa gtatcttcta tatttttagg taatattatt cttttcaatc
    29641 tatcacctcc ttcaatatgg atttctttca caataacatt atctcacata ttttattgcc
    29701 tattgttgca atggtgtata taaagtgttg taaaattgtc ctatttttta taatatctca
    29761 ctcaatttaa atatcatctt tttctttaaa ttgtagcaag atgttctatc taagtgtagt
    29821 ttcatagaaa tatatgtcat attgtttttt gtcttactat tataaaaaag attaaaaaat
    29881 tccatttcta tatcatttag acacgttaga gcattttcta tcttctcttt ttctatttct
    29941 atatcttctt tttccatttt taattttctt aatctttcct ctctttttaa cacctcattt
    30001 tccacagaag agcttatgtt atatgtgtta ctagtctttt ctgtatatac cattgctcca
    30061 catccagagt attcattctc acatcttttt atgtccaagt taatattctt tatctttata
    30121 tccaaatact tataattatg taatctttta tctgtttctt taaataatat atcttttttg
    30181 ttttccatag tacttcccct tttttatata cttattatta gcctcaaatt tacaataatc
    30241 tctttagtgc acagtttttt actaatctca tagctttcaa gaacatattg ttctataact
    30301 gtataaaaaa aacttcttct atattttgtt ctaaaatact ggaaatcttc ttagccataa
    30361 gaagtccagg attttttatg cctctttcta tttgagatat ataatcattt gtaattccag
    30421 cctttctggc aagttgaatt tgtgtcatac ctttgcattt tctataatat ttcaagttat
    30481 ttttaaacat tgttttatac ctccattact attaagaata ttttgttctt cttcacttag
    30541 attatataga attatttgtt ctttatcaat agattttaga aaaaaatatt cttttatatt
    30601 ttattagttt tattttttag aacaatttgt tataatctat acataaggtg gtgttataat
    30661 gtttgccaaa agattaagag aacttagaaa ggaatttgga ttgactcaaa gagaacttgg
    30721 agaaaaagta ggcgtttccc aaagagtctt aggctactat gaaacagaaa acagatttcc
    30781 tgatgaacac attttaaata aattggctga tgtatttaat gtatcagttg attaccttct
    30841 tggaagaacc ttagttaagg aaaatattga tacagtagct gcacatagaa aaaatccaca
    30901 tgaagagtta cctgaagaag cacaagaaca acttaatgat tatatagaat ttttactaaa
    30961 taaatataaa aaaaaataaa ccatatgatg agcagtctat ttttctgctc ttttaatata
    31021 atttaaaggc aaacatacat tctattttag ggggattttt atgaataatt tggataagct
    31081 ttttgaatta gcttctcaag aagagatagt aattcattat accacttata ttgcaggtga
    31141 tttagaagga ctatatataa acaaacatgg tattaaaatt atatcattac tcagtaattt
    31201 aaaacaaaac tcaaaaaaat tgacatccat cttagctgaa gaacttggac atcatttcac
    31261 tagccttgga tactatgtat cctcttataa cgattattat acaaaaatta ttatagataa
    31321 gtgcgaaaat aaagccttaa aatgggcttg tgagttctta attactgaag aagatataat
    31381 aaacataatt aactctggca tcacttgcgt ttatgaaatg gcagacatac ttaatgtgga
    31441 tattactttc tttcaaaaaa gattagaatt tttatcatta aaaaaacagt ctttacaact
    31501 tggaaataat aaatatttaa tattaactaa tttgccgtat ttctacatat ttgatccaat
    31561 ttcataataa aaatagtagt aattttaact ggcttaacag taaaatctat atatttattt
    31621 taacaaattt tggtttctat aaattcaata ttaatatata ataatgatat catattattt
    31681 aaaattctaa aaacaaatat atgcttttgt taagaaaggt tgtttgatga atgtataaag
    31741 aaaagttgtt tgataattat tttaagttct tagcactatt attttggcca attatgtggt
    31801 ataagtggat agtaatttca aatggtactc ttgaaaatat gttatttacc atatatgcaa
    31861 tcgtcgcaat tgttttcatc attttatatt cggtgtttat gataaaatat aaagacatta
    31921 cacaaataga tttcttttac aggataagta ctctacttgc ttttatattt acacttttta
    31981 gctttttaat atacccaaag agtttatttt tcttgtattt aaagattatt tttactggaa
    32041 tataccttta ttattcaata gtaaaaactc ttaaatttaa agatgacgaa ggtgtagtgg
    32101 gtattatgag ctcactttta ttaattgtaa taactttgtt ctactaaatt taattctatt
    32161 tgacttaata tggctttaaa tattagacat ctacattatt ttctgatatt atttaagatg
    32221 gtagtcttat attaataatg aaatacacta tgaaggagtt aactattatg gaaaaaaaag
    32281 ttttagcaac agttggagaa aaagagataa ctaatattga tattgaaaat gcattaaaat
    32341 cattagaccc ttatcaagct atgcaattta aaactgaaga aggaaaaaaa cacttattaa
    32401 atgatttagt gaatcaagaa ttattcttct tagatgctaa agaagaaaaa ttagatgaag
    32461 aagaaatatt taaattagaa atgaaaaaga tagaagaaaa tgtattaaag caatttgcca
    32521 taaataaagt tttatctagt gttaatgtaa cagaagatga aaaagtaaaa ttctttgaag
    32581 ctaataagag ctctttctct aaaccagaaa gtgcaactgc taaacatata ttagtagata
    32641 gtgatgaaaa agctaaagaa atacttgctc aaataaaatc agaagaaata tcttttgaag
    32701 atgcagctct taaacattct tcttgcccat ctaaagatat gggtggtgat ttaggaacat
    32761 tcggtagagg acaaatggtt cctgaatttg aagaagctgt gttctctatg gctaaaggtg
    32821 aagtaagtga accagttaaa actcaatttg gataccatat aataaaatta gaagaccttc
    32881 aagaaagtac agagtctaca tttgatgaag ttaaggctga agttgaaaaa agtttattat
    32941 atcaaaaaca aaatgaagtt tatggaaata agataaatgc tcttaatgct aagtacggaa
    33001 accttgtaaa atacaacgat taatcataag gtcacatata aaaaagctgt cttttcacaa
    33061 tatttattag aaaagacagc tttttatatt aaagtttaaa tattcagttt catattatca
    33121 ttcttttatt gtaaagaact cagcttaaaa gtttaaataa gatttttaat tatcattagc
    33181 taaattttta tatccacgta ttatctcata acagtaacct attacatctc ttctttttat
    33241 tatcccaata aatgtgtctt ggtcatctat aacaggaatg aaattttgat ttaaagattt
    33301 tataactaaa tcttcaatat ctgcgttgat ggaaacagga gaattatcca tttttctatt
    33361 tatatctgtc actggaacat cttccaatcc ctttaagtcc agatttaaat cattttttaa
    33421 tgtccataaa aaatcacctt ctgttatagt tccaacatat ttaccatcct tacttattat
    33481 tggaattgca gagtatttgt gatattccat tttttctagg gcttgcctta tagtgtagtc
    33541 ttcatatata tatgctactt cactttttgg tgttagaaag aataatatgt tcattacact
    33601 acccaccgtt actgaaaact tataaatatt actcaatatt tataatgtta cttttttgca
    33661 gtaactttct cctttcttat tttctaagta ttcttaatac tatacgctgt aacaagcgtt
    33721 tttcctttgc tcattttaat cttattatgc tttattaata tttttatatg gtctatcagt
    33781 atcacttatt ctctttttag aaaatttact aaaaattaat tgacttaaac ttagccataa
    33841 taattttact ctacactatt aattttaaca tatttatctc attattaatg attttatttt
    33901 aataatttta atttattttg ctattaattt tatttacaaa aactgaaaaa accgctaaat
    33961 gattagcggc ttatctctca tattactaga acactaatat atatgaattt ttaattataa
    34021 tctaactacg ttagcagctt gaggaccttt agctccatct actacttcga actcaacgct
    34081 ttgtccttct tctaatgttt tgtatccatc tccagttata gctgagaaat gtacgaaaac
    34141 atctccttca ccttctacag atatgaatcc aaatcctttt tcgttgttaa accatttaac
    34201 tacaccagtt ttcattaata aatcctccta aaaaaacaca aatatttagc tactcttttc
    34261 tgtaacctta ttactactct atcatatata gctatgtttg tcaattatta ttatttttat
    34321 acattaataa tcaatttttt tactttataa ttttaaatga ttattatctt ttacacttta
    34381 tttttcttta taatttttta ataatttatt tttattatat ggaatcttat ggacttatca
    34441 ctccaaccta aatcccatgg caccaacatt ctatcagtat tatgacaagt taccaaagga
    34501 taccctcttg agtctaatcc tgtcactgtc gaaacatgtg ttattctgcc tttcttctca
    34561 taaccaacaa aatcccctgg acgtaaatta taagcttctt tgtatacttc ttcataggaa
    34621 cctttagcaa ttaatgaacc tcttccacta tacagtgcat aatttttaaa agcttgtgca
    34681 tttacccatg cttttgtacc tgctctctcg ctataattcc aaattgagtt ctttttgaac
    34741 cttccacttt caaacattat ctgtgatgca aagtttgcac aatctccacc ttctggatta
    34801 taatccctat agtttggatt aaatttcata ccatgttctt catcagctgc ggctccacag
    34861 tatttatgtg cataatctat agcctttttt tgttcatctg taagctgtaa ctctacacca
    34921 tcttgttgac caatataatt tcttatatca tcagatttta tattttctaa atttaaagag
    34981 tctgcaaaag ggtctgtata ccactcttta gttatgacat attgattatc tataattttt
    35041 acatttagat aatgatatgt acctattcta aaggcatttt ctttgtcctt ttgattttca
    35101 tatgaatact tatattcagt cgatactgaa cagattatac catagaggtc tttttctttt
    35161 tcttttattt ttttaatctt aacccttgtc tttatgtctt taaattttac accttgctta
    35221 ctagaccagt tttctaaata cttcatcttt tttacttcat tttcataagc ccacagacca
    35281 aattttttat ccgtctcata aagacctttt aaaatgtttt catttttctc taatatcgcc
    35341 ttatttctgt agtcaaataa gttttcaagc aatagtttat attggtcttt tacatcatca
    35401 ccttcaacat ttgcagattc catgactttt tcttccatat ttttcatact taaatcattg
    35461 attaaaaata cacctgctgt agtagctaaa gacaaaaata caaatgccat tatacctttg
    35521 atgtacttat tcttattttt cagtattttc aaagctacac ctcccaaata gtacacctta
    35581 caaatcaaat tacaaagaat attctgtcac atatagtaat tttcatattt aataattctc
    35641 tattttatta tgtccaatat taaaaattaa ttgtatcaat acactgtttt ttttacaatt
    35701 ttttatttta taatctactt ttttcttttt tttatagtaa tatatatgta tataaatatt
    35761 ttggtatcat tataattaat acatactaat ggagggtttt ttatgcaaaa aaaagtcgca
    35821 gcaattaatg acttatctgg aataggaaaa tgctcattat cggttgctat acctatactt
    35881 tcagcattaa aggttcaatg ttgtccattt ccaacggcca tactttcaag tcaaactggt
    35941 tatcctgaat ttactttctt agactttact gatgaaatgg taaaatattc aaatgtttgg
    36001 aaaaatttaa aagtcaattt tgatagtata tatagtggtt ttttgggttc aaagcatcaa
    36061 attgagatag tggctaattt tataaacgat tatcccaatg cttttatcgt agttgaccct
    36121 gtgatgggtg ataatggagt tatgtatcca atattcacag aagaaatgag acaggaaatt
    36181 aaagaattag ttaaacattc agatttaact actcctaact taacagaggc ttgtttcttg
    36241 actggaaatg attatactaa aagcgattat aatagagatg agcttataca tattgcaaaa
    36301 tctgtatctg atttgggacc tagcaaagtc gttattactg gtatattaga agatgataat
    36361 atattaaatt tggcttacga tagagataat gaccatgtat tctttacatc agtcaaatat
    36421 aataattgtt cttacagtgg aactggagat atattcacat ctatactttg tggtatgtta
    36481 gtaaataaac atgatttggg agtagcggtt aatactgcaa cagattttat atataaaact
    36541 ataaattaca catctcaatt tgatactgat agaaatgatg gagttatgtt tgaaaacttt
    36601 ttatcagatt taactaatat ataaaatcaa aaaaactatc cattttataa atacctataa
    36661 atcataaaat ttaggtattt acaaaatgga tattatttac taaactattg gtatttcaat
    36721 tgttaccata gcaccaccag ttttcacaga attttcaata cataaagtcc cattatgttt
    36781 ttgtacaata ttatttacaa tatagagtcc cattccataa tgagatttag aatttctact
    36841 caaatctcct gtataaaact gttctgtagc ttttgacaaa tctgctttag aaaaaccact
    36901 tccacaatct gtaactacaa attttaagta tttattacat actgatacac ttatgtatag
    36961 tttactctgg cttggtgaat aatctatagc atttgaaatt atattcataa tagctctgaa
    37021 taacagttct ctatctatag ttatattttt aggcaaatta tcttgtttat aaaactccac
    37081 atctaagttt ttagtactag ctaatgcttc tatttgcact aagacatctt ttataaactc
    37141 actcatactg attgcttctt tatttaatat atagccattc tctgtttttg atatatctat
    37201 taaagtatta atatattttt ctatttgagt gacacccttt gagatatatt ccatgtattc
    37261 taataactca ggattttcat ttatttcaat taataagtca gtatttccat gtataattgt
    37321 tagtggtgtt tttatatcat gtgccagtgc agatatctgt tcctttctat tttcttctag
    37381 catccattgt ttttctaaag aatcttttaa cgccaacttc attttatcca tagaaaaaag
    37441 gacattatta atttcataaa ttttactaga ttctacaaca aaatctaaat cctgttgttc
    37501 tattttttct gtagtatttt ttaaaagctc catttcaata ttaaatttct tgccaaatac
    37561 ttttgataat ataacaattt caataaaaaa tattatacta aaaataatca tacccaatgt
    37621 ctctggtttt ggtaaatatg ctcttaaaat tggagaacta tactctgata ctattttgta
    37681 ttttattata aaaacttcat ctttcttaaa aaactttata taactttctg aatatgcatg
    37741 cctttcttca atatctctca ttaaattcca tacttctttt gattcttttt tattaaaggt
    37801 acctgaaatt aaattcccat ctaaagtata aaccccatac tcatatatac ttggaattat
    37861 atcttcagtt actttttcac ttgaaataat ctgttcttta tatttattga attgtttttc
    37921 tgcataatta gctggtaaaa ttacacctga tgataataat acagaaaatg ataacattaa
    37981 aaggagtaca attgaaattg tcataataaa gaataaagat aaatatttta taaaaatagt
    38041 tcttaacttt tcaacttttt tgttgttaga ttttttacct ccaagcattt gtaccctgtc
    38101 ctccaatagt ttaattaatt cataattaat acctagccag ttttttattt gattatttta
    38161 tatcttttta ttgctaagtt atattttaac ataataatat aaataaacag tcaattttta
    38221 ctctattctt ctgatttttt accttcccat ttagaaaacc aaatacataa aattacaaat
    38281 gctaaaattg ttacaaaacc acaaattaaa cctgttgatt gatatgcttt tattgattca
    38341 acctttatat attcaaccgt tttagaactt gaaaaagacg accaaatagt tataaatcta
    38401 acaccccatg cacaaggaaa atactgccaa ataccagaac ccaatccagt taataataat
    38461 gctgaaagta acatttcaac tatacctact ccaattgatg ctccttttcc gaaccttaaa
    38521 cttaagaata aatgtaatat gtattcaaat aaattacacc caattaaaat tagaattgaa
    38581 atcatataaa agcttgatgt aaagtaagcc ttagatatac caaatttaaa acctaataca
    38641 gacactaatg ttgctacaaa accaagacat actaagatta tatatttact tataagagta
    38701 agatattttg gattagatgt tgttaacata tgtttataat tccctgcata atattcttgt
    38761 tcaacaaaca ttgaacacac aacacctgac aataaaggaa aagctattgc tataacttgt
    38821 aaatatccta ctatctttag tatattatca gctcctgaaa ccttataata ccataaaaac
    38881 aatcccatcc ccattaaagc aatgcaaatg tgcattagta ttataaaatt tctctttaat
    38941 tttattaaat cagaacaaaa tattcttatt aactgtctca tattacttca cctctctatt
    39001 attgaaccaa acccttgtag ctaaagcaaa taatacaaat aaaacaatag atattaatac
    39061 tcctggcaaa ataacagcat tatttaaaaa ttcacttccc tctggtacag gaagaccatt
    39121 tggcagaata tgcaatacaa cagccattaa tcttgaagga atcgaatatg gaaacatata
    39181 ccacatttct gtagttgaga aaacagcaac tccaacaata gtgaagaaca tatttattag
    39241 aactgtaaca aatataccaa attttgaagc taaaaacata caaagaggaa tctgccacat
    39301 aaatagtaaa ataattaata tagttgcaat gatattttga cctattgaaa tagtttcttt
    39361 atagattatc ccaacaaaaa ctacacctat tgcagaaata attgatgcta taaaacaaca
    39421 aataatacag taaatcattt ttccagtcca aacgtctttc atttcaattg gcaagggtaa
    39481 aataccacga tatttacttt tttcatcttt taatactatt aaagaagata ttaatgttaa
    39541 tgctcctgga agaaatgtcg tataccacca gttgaaagca gcattttgcc ctccacctag
    39601 tccacacaaa agtatacaaa acactggaac tatccatatc aacttcattc caaaagttcc
    39661 tttcatcttt tgaaattcca ctctaataaa tctttccata ttactcccct ctctttctat
    39721 tttcagctac aactttcata aaaagttttt ctaagttttg ttcttttgat acttctcctt
    39781 gataacccat tactccatta gaaattattc ctatttcatc tacaacttgt tcaacttcag
    39841 acaagatatg gcttgataaa ataactgtaa ttccttgttt tggaaaagaa cgaatcaatt
    39901 ctctaagttc ttcaatacca atagggtcaa gaccatttgt aggctcatct aagattaaaa
    39961 gttttgggtg atttaataat gcaatagcaa taccaaggcg ttgcttcatg cctagagaga
    40021 attgacctga acgcttttta aaggtatctc ttaaatctac agtctctaaa acttcttcaa
    40081 tgcgagagtc aggaagacca agtaaagtag tatgaacttt taaattttct cgtgctgtta
    40141 aattctcata tatagcagga gactcaataa gagaaccaat atttgataaa tcctttctag
    40201 tccatctatg tccctcaaac attatttttc ctgaagttgg atttaaaatc ccagttatca
    40261 tttttaataa agtagatttc ccagctccat ttggtcctaa taatccatat atagaattag
    40321 atttaattgc tagtgaaatg ttatcaactg ccatctgctc cttaaatttt ttagaaactc
    40381 cttttacctg caaaatataa ttactcataa ttttcatcct ttcttttgtc aaacttattt
    40441 acaagaatca ttctaaatca taaatataag gattttataa gaattaaaaa acaaaaaaag
    40501 atgtgttaaa aacacatctt tttttatctt aattctatta attttccatt gtagtatatc
    40561 tctacttctt caatccaaat gctattatct tcttcttgga tgacattttt aataatatta
    40621 tttatagtat atattatatt ttgttcattc aaataatcat ctttccaaga aactctactt
    40681 tttttatctg gttctatcaa gtttatttta acaagattat ctttttcctt aacttctact
    40741 tccatgtcta aaccattaaa atactcattt gataatgtat ctaagattaa tcgcagttta
    40801 tccttaagtg aactttcttc atcaatctgt aagtacttta ctattttctc atcctttgaa
    40861 attatctcta taggtatttt agtagttttt ttagaattaa tcattttact agttgtttct
    40921 tcttttgcat cttcatcctt ctttacaact gctgattctt tagaatcaac tagctcaact
    40981 gcactgatgc tataatccat acatgccgta ctcaataaag tagtagcaat tattaaaaaa
    41041 cttactgcta ttttattcat aagtatccct ctcctaattc tctttcgata cttattatac
    41101 catagtatag attatatttt tatactttta aatcaattta taaattatta tagtaaatta
    41161 tttacaattc taagctattt gaatttattt ttatagtata ttctttctct aaattcgaca
    41221 gatttttatt caaaagccct tttatttccc tcgtatttct atacttgttg ctatgttctt
    41281 catcatgttc atagtcatat gaatcattgt catattcttc atcattatta aattcttcaa
    41341 ttgcttcttt tgactttata tcacaattaa atttatactt atttactggt atatcaagtc
    41401 ttaccttaga atttggaact tctatgtcca ggaacttagc aattggcata tcagagtaca
    41461 agtaaaattc actttcataa tttgaatttc tacctatttt ctcttttata tttacatttt
    41521 caggtatata ctcttctata ttattgataa atacatcttc attctctgaa gatatataca
    41581 atgactctga ttctatgttt acatttttaa cgcctaaaat tgattttgtt gacaagtgaa
    41641 gattgttatt agatattaag tttaggtttt ctaatctatt tactttgttc tctgttatag
    41701 ctctactaaa acctccataa gaagttttat atgttatagt atttgaagct acattatcgt
    41761 atacaaataa gtgtgagctt atacttgatg catttatgtc tacattattt ggtacatata
    41821 ttataatttc tctataatca tgtgaaaaca tactatttat agatgtattt aataattggt
    41881 cgaaattttt aatcttttta attttatttt catattttct ttcacctttt acaactaaag
    41941 tcttatcttt taaagttaca ttgtatttgt aaaactcatt atttcctctt gttgttacac
    42001 gcacatcttc acttgaactt ttctttattg taacgtttat attgtcaaca gctatatcta
    42061 acttgtcaat atttactttt tcttgataaa gtttattttc ttttttaaat tcagcttcct
    42121 tttctaaacc aaagtttatt aggcttggca taactaaaat ccctgaccat gttgtcccta
    42181 ttatacctat taccaataaa actgcagcaa atatagcaag ttttttattc atgtttatct
    42241 tctcctttct tattttctat atcttcaagg tccttatata tcgcctcaaa atttatacta
    42301 tcatcattat attcatcagt ttcttttatg ctttcttctt ctctattgta gtaatcatta
    42361 ttatatgaat cttcattaat gtctttattc aaatcttcat taatgtcttt attcaaatct
    42421 tcatcattta aagtagcttt ttttcttttt tccatctttt catttgcctt tatataaata
    42481 ttttttctct ttatccaatg tatataatta tttagtaatt gtttacctag ttttatggca
    42541 aataataaaa tttgccatgc aagtatctca agccctacaa atgctatggt tgcgaaaata
    42601 caaaacatca taacatctgg aaccattgct ataaatttaa tcacaaatgg aattaatata
    42661 acaaaagcaa ttaatgagca tactaatgca atagtagcag atacaatagc acatacaaac
    42721 gcaaatgctg gaacaattag aaataaagat aacactacta ataacccctt tataacttgt
    42781 ctggataatc ctcctacgcc ttcttctata cttggtgtaa gtttatcatt tatattttct
    42841 tttgatttat tgtacttttc cttagcttca tctttcaaga tagagtaatc cttttttaca
    42901 tttgatttaa atctactaaa tttaccattt aatatgtctg tattcattat ttttccatct
    42961 atattttctt ttgatttact atacttttct tttgcttcat cttttaagat agagtaacct
    43021 tttttcatat ctgatttaaa tttactaaac ttatcattca aaacatctgt atttattatt
    43081 ttttcctctt caatattttt ttctttagtt tgtaagataa gttcttttgc tatagatttt
    43141 ggtgagccaa gtgatgctat tatctccata tcactctttc cctctataag accatctacg
    43201 aaatactctt cataatctct caatatatca ttaacttcgc tctcagaaaa atcttttttt
    43261 agataatcct ttaaaatttc aagaaactca gttttattca agttcattac ctccctcatc
    43321 ttcacttatt aaaatctcaa cagcctttac aaattctctc cactcttcca tcagattgga
    43381 taaattctct tttcctagtg aagttattct atagtatttt ctagcaggac cttcattaga
    43441 ttctagtata tatgtttcga aatacaaatc ttttgtaagt cttcttagaa taggatatat
    43501 tgttccttca tttacatcta ttactttaga gatgttatgt actatctcat atccatacat
    43561 atctttctta gatatgagag caagtacaca aatttctaaa acaccctttc taaattgtgt
    43621 gttcatatac tccatccttt ctttaaatac acagtattgt gttttacaag gtactatgtt
    43681 aaaacttctt atatcctcat aataacacag tactatgttc tgcacaatag ttatttttaa
    43741 atattcttgt tgattaaatc cttctataaa tgtataatac tctaatcaga tatattttat
    43801 gaaagtggtg ataaattggc taaaatgaaa gatgataaaa caatattaat cctaactgct
    43861 caatttggtg ctggacatat aagtgctgca aaagcagtca aagaatgtat tattgaaaaa
    43921 tatagtaact ataatgttgt tatacaaaac tttataaatg caagtattcc catgatgaat
    43981 aagcctatgg taaaacttta tgaaaacaat acaaaatata ctcctggatt atataattac
    44041 tattattact ttaagaaatc gtttgattca agacatgatt tatctcataa attatataca
    44101 cctaaacttt ctgagtatat tgctgatata aatccagatt tgattatctc tacatttcca
    44161 ctagctgctg cttgtgtaaa taactttaag ataaaaaatc ctgatataaa tatacctaca
    44221 cttacagtta taacagatgt tgtagatagt atggaatggg tttttgaaaa tacagatttg
    44281 tattttgttc cttctcctga aataaaaaat agattttttc agaaaggaat aaatcctgac
    44341 tccataaagg ttactggagt tcctgttgat aagagatttc aaattgaaag taaagaacta
    44401 tgttgtgata aatatagact attacttcta ggtggaggaa gaggtctatt tgatatagat
    44461 gaggatttta tgcattggat agatgaattt attgaagaac atagtaattc tatagaaatt
    44521 acaatagtta ctggtaaaaa caaaaaatta tatgacaatc taactcataa aaaacctcta
    44581 aaaaatatta aagtacttgg atttgtaaac gacatgtata atctaataag agaatgtgac
    44641 ctaatgctaa ctaagcctgg aggagcaact atatttgaag ctattcaatc acaaactcca
    44701 gtactcgtaa aaatgccaaa agttggacaa gaaattgaaa acgctaaatt tataatagat
    44761 aagggtcttg gcatgattta tagtgatgac ctagacctta aaaacatatt ttataaatta
    44821 gtatcaaatg aatttgattc tataataaac tttatgaaaa aaaatttaaa agaatttaaa
    44881 acagtcattc atccagagaa aattgctgat tatatatcag aattaataga taatcattac
    44941 agttaaattg tactattaaa aaatttcaaa cataaaatta aaggcaatca agtatgcttt
    45001 tacacttgag aatttactca tagtgtttaa taatacttga ttgcctttat catatcaaaa
    45061 tcaaattgtt atattagtat atatttttct tgtactgcat atacagttgt tgtatttctt
    45121 ccatacttct ctttaattct atttgtaaat ctgaagcagt ctggtaatcc ttattttcta
    45181 tagcttctct cactctagtg aatagtgatt ctctagttaa agtatccttc ataatattga
    45241 actttaaatc cgatattgag ttccaaacta cctcatcaag cgcatccata ttttcttttg
    45301 tgtgtatctt gacaatactt cttatttttt gaatcccagc ctctattatt ctagttttta
    45361 atttcttttg ccacttatct atagctccaa tcttaaatga ttctattata ctatcagtaa
    45421 atacatcacc ttgttttaaa gattttaatt ttgaagcata tatttctaag tttttcatat
    45481 tttcataaac tgtagctggt ggtattccaa atcttgcatt tctttcttcc aaactataat
    45541 gttcaaatac atcattttca tctctatatg ctctatcttt ttctaaatag aaactttctt
    45601 cacctacatt tttagataac tctttttcaa gttcttttgt actaagacca ctcttagctg
    45661 ctgcttttat accatccaac attgtttgat aacatcctgc tattactaaa tacgtgttag
    45721 atagagggct tggtgacctt aattcaaatc ttacagtctt tggatttttc atatctctta
    45781 ttaatccaac aagcactgac ctatttcttg atggaatctc ataactatgc cctaaagatg
    45841 taactatgca tacaggagct tcaaatccag gaactaatct attaaatcca tcattagaag
    45901 ctgttacaat tgggtttaat acttcataat tgtaaagaag tcccataaga gccccatatc
    45961 ctagttcact tagataatct tcttttaaat cttttggagc aaatagattt tttatacttc
    46021 catcctttaa cttcgcactt actcctacat gtgtatgtcc accacttcct gctactccat
    46081 gaattggttt tgctttaaat gtaacttcta gtccatgtga tgtaaataca tcctctataa
    46141 catctcttac taataattca ttgtctgctg cttgtaatgg tgtagaaaac ttccaagaaa
    46201 cctctaattg ctccatagca tggtttgttc ttccatctat actaatagaa ctttgtattc
    46261 ctccgacctc tttgtgagcc atttcagggt ttacacctag cttttgaagt ataattaaac
    46321 ttttctctaa acaagttctt ataataccat gagttctttt ccagtattgc tcttttaggc
    46381 tttgtgatac atataatttc tctaagtcag ctttatcctc aggagtatta acccagaact
    46441 caagttctgt agctgctgtt aacattattt cctctatatc atctactgaa tctattccta
    46501 tgttatttat tacatgtgga tattctctaa atatttcata cattgacttt ttaaagtact
    46561 tatctgcttt ttgaagtact cctctagaac atactttttt attatcatgt attaaaaatg
    46621 caggtatctt taatgttcca acaggtagac ctacttcttc gtctatatat tccatattgt
    46681 aatctacata ccaatgacaa cttttatctg gcattaaatc tactttcgca ttatttaatg
    46741 tagctatatt ataaagctca acacttgaac catcagtctg tatagctgat tccaaaaatt
    46801 tatctatatc ctccaaaaat aattctacag gaatcttttc atctgttgca tttcctccta
    46861 aatcaacccc cattaaggaa acaaatctta tatttttatt gctttttagg atttctctta
    46921 attcttcatt agtgtgttta tctttctcta ttacgtataa tagactatcc atttttccac
    46981 tctcccataa tttttatgta tattttattt tgttaaatac aagataaatt tcattttcct
    47041 tacatttatg aatttttctt gcaaattatt cgtgttttat tcgtgttttt atttatatta
    47101 ttatatatca agtataaaaa gttcgcaata ttttttattg gaaaaaatat tatacataca
    47161 atagtttaac atttttacaa atatggggta tactaaaata aaagtatttt tatttgaaaa
    47221 tttaatttta tttataatat aatctatagt aaaagaaata ataaaaaaat ttaggagata
    47281 aactttatgg aatacataat tttcgatttg gaatttaacc aaggatttga taaaaaactc
    47341 aataaaactg tatccaatga aaagtgtcct tttgaaatta tacaaatagg agcaattaaa
    47401 ttggattcta aattcaatat aatagatacg tttaatagct atgtaaaacc tacaatttat
    47461 aaagacatac atccctttat tagtcgtatg actaatatta aaaattctga ttttaatgat
    47521 tcgcctactt tccctgaggt ctacaacaat tttataaaat ttatatcatc acaagaccct
    47581 atattatgtg tttggggagc tggagattta aaggaattat acaggaatat caactatcac
    47641 aagctaccat caaattcctt acctaaatct tatattaata tacaacaaca tgcatctaaa
    47701 tatttcaata atccagcagg aaaaagcatt ggcctacaaa atgctatttc tatattagaa
    47761 cttgatgaaa aaatgtctta tcacaatgct ttaaatgatg catattatac tgctaaagtt
    47821 tttattaaga tatacaatcc aagtatagtc ccagatatat atctttatac gagtataaaa
    47881 cctaaaacta taagatattc taataaaaaa agagttgatt atgataagtt atttgatgaa
    47941 tttaggaaaa ttttaaatcg tgaattaact aaagacgaga aaaaaatcat taacttagct
    48001 tataatatgg ggaaaacaaa tcaatttaca ttagaaaatg ttaagcaaag aaaaaacaaa
    48061 tagagtttat ttagataaaa aataggcatg tagattaaaa aactagttaa ctttaaattt
    48121 atatctacag cccaattttt atcataatta atttttattt tatctctaat tcaactggac
    48181 aatggtctga acctaatatt tcagtgtgta tatccgcact tactaatcta tcttctaatt
    48241 ttttggatgc acaaaaataa tctattctcc accctgcatt attttttctt gcattaaatc
    48301 tatatgacca ccaactataa acaccttctt tatcaggatt aaaatatcta tatgtgtcta
    48361 taaacccact gtctaataat ttagaaaact tctctctttc ttctttagta aaacctgcat
    48421 ttttcatatt atttttagga ttttttaaat ctatttcttt atgtgcaacg ttcatatctc
    48481 cacacacaat tacaggctta tgattatcta gtttggttaa ataatctata aagtcgtctt
    48541 cccatctagt tctatattct agtctcttta attcagattg agaatttggc gtatatactg
    48601 taacaaagta aaaatcttca aactctagag ttatcactct accctcttta tcatgttctt
    48661 ctatatttat tccatacatt acttttaaag gctctttttt tgtaaatata gcagtacctg
    48721 aataaccctt tctctcagca taattccaat attgaaaata tcctggtaaa tctaactcta
    48781 tttgcccttc ttgcaattta gtttcttgta aacaaaatat atctgcatct acttctttga
    48841 aaaagtctaa aaatcctttc ccaacacaag ctcttattcc attaacattc catgatataa
    48901 atttcatact tatactcctc atctaaacat tgacacactc cccatagcta aagatggggg
    48961 cttttcaaca attttattgt aaattcttaa ttcactttta ttttaacaat gctatactat
    49021 aatttcatct aaaattacta tttacttaat acctaaaaat atatgtttta atcaattttt
    49081 aacttttttg ttaaatcttc agggctcatt gaagaaacat acatatttgt tccaagttca
    49141 aatcctccaa aattatattt tcttgggatt atgtgcatat gaacattaaa atacgatttt
    49201 gtttcaatct ttgttggatg agtgtgaata cataaattaa atggcatata tccattgata
    49261 ttgtataact tcttaaacaa cttttcaaat attgtagaaa gctcctgtat attattatca
    49321 tttaactcac caaactctat tttatcttta aatattattc ttacttctcc actatacttg
    49381 gttgcatatg gtataagtac caaaaaagct tctccattat aaacaactct tctatctaaa
    49441 cttatttcat tttctattaa atcatcatac aaagagcttt tattgctgtc ataatactcc
    49501 tttgaaacca acagttcatt cgtaatttca ggtggaataa aagacataga caatatttgt
    49561 gcatgtggat gcatcaaaga tgctcctgcc tttctcaaga agtttttgaa gatactaaca
    49621 tactctactt tatcatcttt cgacaaatct ctaaatctat ttctatacat aaaaaaaaca
    49681 tcttcaaatt ctttttgact catgttataa aaactacgat tatgtttatc gctctctatc
    49741 attacttcat gaacaccata tacatctctt gccatatcat caattatagg aaatttattg
    49801 tagacagatt ttacaagcca tccttcttca ctatctattt caaataatgc atcagttgca
    49861 tgagcttcat ttcctttgca aaatgggcat tcttcatcat attcattagt ttcttcatct
    49921 tcatttggga tatctgctgt atctaaaggt ctttttaacc tatctgtagc aaatataaca
    49981 acatcattgg taattggatc tattcttaat tctttcataa ttaacacctc ttagttaata
    50041 gcctttaata taattatatg atatttatcg tatctgttaa ataaatttat aatatttttt
    50101 ataattttgc atatttatta ttatatattt tgtctatagc tgaaagatta taactaaaaa
    50161 atcactatca gtatatcaga atattatctt actataaatt aatttatgaa tacataattt
    50221 agtggcataa acatgggtat tttactataa tttgttaaaa gtttatttta aagctatatt
    50281 aatttttttt gatgattttt acccataagt atgttattat tatcttgtaa agatgtcttg
    50341 tattcaaaca tacaatttac ataatacaat atacgtattt aaattaaata gggggtatta
    50401 aaatgaatta ttcaaacaga gttagtgcaa tgcaagcctc tccaatcaga aaacttgttc
    50461 catttgcaca agcagcaaaa gataaaggaa tcaaagtata tcacttaaac ataggacaac
    50521 cagacataaa aactcctaaa ggattttttg atgctgttaa aaactttgat agcgaagtct
    50581 tagaatatgc tacatcagaa ggtattccag aattattaga agcacttcaa aattactata
    50641 aaacttacga tatgaatttt gaaaaagatg aattattagt aactaatggt ggtagtgaag
    50701 ctttactttt cactatgatg gcagtttgtg acccaggaga taatctatta gttccagaac
    50761 cattctatac aaactacaat ggatttggtc aatctgtaaa cgtagaagtt aatgctgtta
    50821 caacaaaggc agaaaacggt ttccaccttc catctaaaga agaaatattg tctaaagtag
    50881 atgataaaac taaggctata attctttcta acccaggaaa tccaactggt gcaatttata
    50941 caaaagaaga acttaatatc ctagctgaaa tagctaaaga aaaagattta tggataatag
    51001 cagatgaagt ttatagagaa tttgtttatg atgggcttga gtatacaagc tgtggtaact
    51061 tagagggtgt acaggataga gttataataa tagacagtgt ttctaagaga tacagtgctt
    51121 gtggtgctag aattggttct atcgcttgca aaaataaagg tcttatcgct caaatcctta
    51181 aattatgtca aggaagactt tgtgttccta cattagagca aataggagct gttgagttat
    51241 acaaaactcc tgtttcttac ttcaaagaag ttaatgaaga gtacaaaaaa agaagagatg
    51301 tattatacaa tgaattaatg aaggttgaag gtgttatatg taaaaaacca actggtgctt
    51361 tctatatagt tgctaaatta ccagttgaaa atgcagaaga tttcacaatt tggatgttaa
    51421 aagaatttaa caaagataat gaaacagtta tggtttgccc tgctgaagga ttctatgcta
    51481 ctccaggttt aggacgtgat gaaataagat tagcttacat cttaaatgaa aaagaccttc
    51541 atagagctgc tacattatta aaagaaggtt tagagcaata tgtagcttta caaaaataat
    51601 tttttaaact taatttatat aaatttaatg atataaaatg tccccttttc agatattatt
    51661 tgaaaagggg acatttctta attaatatat taattaagac ttagacctga ctatttttca
    51721 ttttctttat atagtgttgg ccagtaatct ttattcactt taattaaagc atctaaaact
    51781 tgtcttgcct tagttagaga aattataaaa aagtacatca agaaaattta agatgtactt
    51841 tttagattgt atttagactt ataattatat agttaaatga ataacaaaga attaatctta
    51901 gtaccattaa atacaaaaat ttttatattt tttctatcta aattcttctt tgtttaatat
    51961 atattgaaga gtatttattg cttctaaata tttttttctg tcttcttcag ttaatttaga
    52021 aagtttttct cctaaaccat cacttaattt atccataaaa tcagttgcta tcttatctcc
    52081 ctcttcagta atgtcaatta gatattttct tctatcaact aaatctcttt tccttgttac
    52141 atacttctta tcagttaaat catcaaccat actagttaaa ctgccttttt ctatatttaa
    52201 cttagagcat aaatcagtca tacttattac tccataattt tttatgaaaa ctaatgctct
    52261 taattgtgtt ttatttacat tataatctgg tgcaaatttt tttaggtctt ctaagtacag
    52321 gctagaataa atcttaggaa atgtttttac taaaaaactt atggtatctt ttactatata
    52381 gttcatataa tcacctcggt tgttttaaaa tttattaaat tatctaaata actttatttc
    52441 agtttacatt aaaaatattg caagtacaat agtttttgct gaatgtttaa atttaattag
    52501 taatcttatc atttttttat ttttatttat attattccta attaaatatt atttatatag
    52561 ctattttatt aaattcatgg tatagtaagt aaagaagaac tcttcacagc ggtggagaga
    52621 agacgctagc ccattaaaat ggctatctta tttataaata agatagccgt ttttaattat
    52681 attttatctg tacaattcta tactcttagg tctacatcta cttttcctaa gtcttcctta
    52741 taatctttta tagcaggttc tacaacttca tttacaaatt ctacaacttg ttctggagct
    52801 ctacctataa agttttttgg gtccattata gatagtattt cttccttgct cattttaaat
    52861 gaatcatcat ttattataag ttcaattaag ttattatcct tgccttcatg ctttactcta
    52921 taggcagctt tcatagaata ttctcttatt atttcatgta attcctgtct atctccacct
    52981 ctttttacag cttccataag tattgtttct gtagccataa aaggaagttc ttcatttaca
    53041 cgtctattta tcatattttc atatactact aaaccatcag ttacatttat ccctatttca
    53101 agtatagcat ctgctgccat aaatgcttga ggtattgcca atctcttatt ggctgagtca
    53161 tctaatgttc tctctaacca ttgagtggct tgtaccattg cagggcttat agattcagag
    53221 attatatact tagataaaga tgctattctc tcacttctca ttggattcct cttataagcc
    53281 attgctgatg aacctatttg atttttttca aatggctctt ctaattcttt taaactttgt
    53341 aaaagtctta tatcattagt catcttatgc atactttgag ctatccctga tagtatgctt
    53401 attacttgat aatctaactt tctagtatat gtctgtccac ttactgcata ggaagaatgg
    53461 tatcccatct ttttacaaat tttcttatct aactctttta ctttttcgtg gtctccttca
    53521 aataagctta aaaaacttgc ttgagtacca gtagtacctt taactcctct taacttcatg
    53581 ttgtctattc tatagtttaa atcttccaaa tcaagaatta aatcttgagt ccataaacaa
    53641 gctctttttc ctactgttgt aagttgagca gcttggaagt gtgtaaatcc aagagctggc
    53701 atatctttgt acttaagtgc aaattctttt aaattgttta ttaaatttac aagctttact
    53761 cttagaagtt ttaaagcttc attcatttgt ataacatctg tattatctcc aacatatgca
    53821 gatgttgctc ctaaatgtat tattcctttg gctttttcac attgtaaacc ataagctttt
    53881 acgtgagaca ttacatcatg tcttacttct ttttctattt ttctagcttc atcaaaattt
    53941 atattatcta tattagctct tagctcatct aattgttctt cagttatatt gattcctaac
    54001 tcatgttcac cttctgcaag tgcaacccat aaccttctcc atgtagagaa tttaaattgt
    54061 ggagaaaata tataactcat gtccttgcta caatatctgt ctgtaagtgg atttgagtaa
    54121 gtagtatatt tattatctat cattatatta gcaccttcct taaatctttt gtcgtgtgat
    54181 tactgtgtac acattagtac ataaataatt atatataatt ttacgaacta taacaagact
    54241 tttttatttt ttgttcacat ttatatatag tattttttat ttattactat tttttattta
    54301 tatccaaatt atctttttca attaagtaat ccactatttc actatcaaca aaatttaata
    54361 catacttata tctaattgca tagtatttat cactccatcc aagctgattt tttacatcac
    54421 tttcatctgc cccaagcctt aaacttattg ctgcaaatga atgtctaaaa tctcttgctg
    54481 aatattgaga aagtccagct aaatctaatg cttttttgac tataagtctg acatttctat
    54541 ctgttataga attactcttt tgagttgtaa aaataaaatc atcactaggt attattacct
    54601 ctggaagccc agaataattc ctgtaatctt ctaaaagttt aaaaaagtat ggatgtaatt
    54661 taactactct ttcttttctt cccttaccta accttacata tgagttatcg ttttcatcta
    54721 ccataaggtc tttccacttt aagctaacta attcatttaa taaacaccca gtagtaacta
    54781 gacagactat tattactcta tctcttatat ttaattttgg taggatacct ataagtttat
    54841 ttatttcttg tatacttaga acatcatctt ttgtttttat tcttgttact gtgggttttt
    54901 ctacatatct aaatggattt atatctatgt atccttcttt ttttaagaag ttataaaaac
    54961 tatgtaaata actatatatc ttttcacaag ttgatttcgc atatttagtc tgtatatagt
    55021 ctacaaaatt tttacaatct tctttcgtag cataaatcaa ttctttccct tttaaaaatt
    55081 ctttaaacag tataaccttt gataaataat cgtgtttcgt gtttggattt aattttgtag
    55141 aaaaaacatt aaaagtttca tactcataat catctagtat ttttgtacta tacataataa
    55201 ctcctttcct tttcataaaa taaaatagct atacttttac tataccatat atttccccct
    55261 caaatatacc ccttattcaa tagataactt ttaagtttat tttgttatat tatgaaggtt
    55321 ttatgaaaat atcaatcttc cattgtgcac tacacagtac tatggtatta taagttagta
    55381 aaaggtggca tttttttatt aatctatgaa taaaatatgc tactataaat ttgtattgga
    55441 ggtattttga tttggaaaca tttagtttgc ttgaaatttt taaggcagtc attttgggca
    55501 tagttcaggg aataacagaa tggctaccag taagtagtac agggcatatg atattagttg
    55561 atgagtttat aaaattgaat ttttcaaata catttataag tacattttta gttgtaattc
    55621 aatttggttc aatattagct gtacttgtta tattttttag aaaattaaat ccttttgata
    55681 gcgcaaagaa tattaagcag aaaaaagaaa cagtccgttt atggcttaag gttataattg
    55741 cagttatacc atctggagtt attggaatac tgtttgaaga tgatatagat agattattct
    55801 ttaattcaac agtagttgct attgctctta ttgtatatgg tataataatg atagggcttg
    55861 aaaagagaaa taaaaaacct aagtataaag atttttctca agttacatat aaattagctc
    55921 tttgtatagg attattccag tgtctagctc ttataccagg tacatctagg tctggttcta
    55981 ctataatagg tgcagtatta cttggtactt ctagatatgt agcagcagag ttttcattct
    56041 tcttagccat ccctacaatg cttggagcta gtgcattaaa acttctaaaa gctggatttg
    56101 gatttactgg atttgaatgg cttattttag gtgttggttc tgtagtagca tttgttgttt
    56161 caattgtagt tattaaattt tttatggact atatcaaaaa acatgacttc aaagtatttg
    56221 gttattatag aatagtcttg ggtatagtgg ttcttgctta tttctttcta ttataatgta
    56281 ttctaattta ataacaaatg ataaggagaa aagttatgag tgttaaaaaa gaaatatttg
    56341 attggattaa gtcaatagct atggctattg tacttgcatt tgtaattcta caatttataa
    56401 gaccttctat tgtaagtgga gaatcaatgt atcctacttt agatgataaa gattatctga
    56461 ttttaaatag gatatcatac aaggttggta aacctgaaaa aggcgatatt gtagttttta
    56521 aaaccaattt agttgatgga gaaacaggaa agaaaaaaga cttaataaaa agagttatag
    56581 ctactgaagg tgacagaata aaaatatcaa attctaaagt gtatgtaaat ggaaaattat
    56641 taaatgaacc atatatacac aataactata cttctggaga tatagatact gttgttccaa
    56701 aaggtaaact atttgcaatg ggagataata gagaaaatag taatgatagt agattccctg
    56761 atgtaggtat ggttgatgaa aatgaagttc ttggtaaggt tatggtgaga ctattacctc
    56821 ttgataatat tgggaaagta gactaaaaaa taagagactg aattggtaaa gtttatttta
    56881 caaatctcag tctcttttta ttttcttaaa ttacaaatat ttttttacta aatatctttt
    56941 gattctgtaa taagtcttat tatatcactt gcttcttcat taaaagttgt tactatactt
    57001 aggtagtctg ttgctctact catagctaaa taaaccttat ttaaatctcc tacaaagtca
    57061 tttacttgat aatcttgttc aatatcattt atagtttgat tatataacat ctctaattca
    57121 catactatta ccgctttata ctctaaattc tttattgcat atatatttgc tattgtagtt
    57181 cctaccttct tacttatatt tgtcaaatta tcttctgcac atatataagg aatttttgcc
    57241 tcttccaatg ctttttttaa catatattga aagtaaatgg tttttccact ttttaatttc
    57301 ttcttattgt aagggtaaac gatagcaact tcagaataat caagaccttt tttacttatt
    57361 aaatactcaa tttcccagat tacagaactt atttggtcat caaggtcact tacttttatt
    57421 atatcaacag acttatttcc acctctaagt gctttagtat aaaagaaagt actaaattct
    57481 gtatttggtc ttaattcgtt tatatatgag ttagaattat ttgaaaattt atttgtaaaa
    57541 tctacaatct ctttagcttg tctataattt ttacttaaga taatcttatc atcaaattct
    57601 ataccattat ataatttttt aaatatattc aatctattag agatattcaa ggagttacaa
    57661 gaacatacat taaatatgaa ttttgtttta tataaaaact cccttataaa atctatttca
    57721 tactctaaaa agctttctgc ttcatcaata aaaatagcct tgaacatatt tttatttttt
    57781 ataatgttct gtgcttgttt tacaagatta ttaaaggtct tttcgtaatc attttttaac
    57841 atattataat ctacaattaa attgaatttt ttagctagtt taaatataaa agaactaaat
    57901 gtgtgaactt ctaaattgtt attatctttg tataataact ctatcctttc tcgaagctca
    57961 ttgcacaatt gttttgtatg tgtaaatatg actaatttat gatgtggata tacttttgct
    58021 aattttatag ccctagaaag cataattgct gttttgccta taccagaacc accttcaata
    58081 agtgtattcc catatttaat agaaacaaca tctttaattt gaacgtcttc catcatagtt
    58141 gctgtatact tatagtcatc attgtagaat gaaatttttt taaatttttc atttagatga
    58201 agtttatcat ttattatata gtattctgaa catatatcta gtaaaaataa atttaagttt
    58261 atttcatcat tctcatcatt aagatattcc tccagcgaac ccttattcat tatatcttga
    58321 agcttatttt tatctattat attattatta acaaattctt caaattcata tgtttcctca
    58381 acttcaacgt atggcataat gtaaacgtag ttataactta tatttctatt cttttgtccc
    58441 atttttagtt tcaaaagttc atattcctca ttcataactt caagtaactc ttcttctaaa
    58501 ataaaaaata tatcttctgt tgtatccata aattttataa ataaaattct tccatcttta
    58561 acatacaaca aatcggtatt tattccttta aaaggagtaa cttttggcac tactttaacg
    58621 tcctcattga tattttcgta aaatattttc tcgaactcct tcaattttag ggcgtctaac
    58681 tgagaattta tatttatgta ttggctcact tacattacct ccttctgtta tacttaatta
    58741 taccattttg aactatattt ttatatatac tttttatagg caaatttagt aaataaattc
    58801 aaaataaata caaataaata caaaactgct aaaataattt tgcaataaat atagatat
//
LOCUS       DAMJXI010000018        56041 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.019, whole genome shotgun sequence.
ACCESSION   DAMJXI010000018 DAMJXI010000000
VERSION     DAMJXI010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 56041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56041
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.019"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            214..2403
                     /locus_tag="PC465_001495"
     CDS             214..2403
                     /locus_tag="PC465_001495"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HDF2648813.1"
                     /translation="MKYIIKRDGTKELFSKSKIEDAVYKASINSEGGVDRELAYDISR
                     KIANDYNSMEKCLSVEEIQDIVEVLLMESNRKDIAKHYILYRERRSEIRTKAWEFDEL
                     QKSIWKNKYRHNGESFDEWIKRISNNSSRISKLIRQKRFLFAGRILANRGLQKEGKKV
                     TYSNCYVIEPPKDSIEDIFDTAKKLARTFSYGGGVGIDISKLRPKGAKVNNAAKHTTG
                     AVSFMELYSMTTGLIGQRGRRGALMISMDVNHPEIEDFIDIKTDLEKVTKANISVRVT
                     DEFMQAVREKKLYNCTFEVETTGEKIVKIVNAYDLFNKFVKNNWDYAEPGILFWDKIK
                     TYNFMSEDKNFCFSGVNPCAEEPLPSGGSCLLGSINLSEFIIQPFGEHATFDINKLKS
                     CVREAVVALNDVLDEGLNLHPLQEQRDSVHKYRQIGLGVMGIADMLIKMGIRYGSDES
                     LELCDLIGKTMLNEAVKQSALIAKEYGTFSEYKYENISKSKFFIENLNEDTKEMVKKY
                     GLRNSQLLTIPPTGSISTMIGISGGIEPIFNLSYIRKTESLHDEDVYYKVYTPIVKEY
                     MDKKGITDEECLPDFFVTAMNIGYEERINMQKVWQKYIDASISSTINIPFETTVEDVF
                     NIYIKAWEAGLKGVTIFRDGCKRSGILINEKKEENNKEDKKENSKKEYYKNNKKEKDN
                     KDEKAKEIINKNFEEDEKFVCPECGSEGIAHTGGCSICLKCGYSGCN"
     gene            2471..3238
                     /locus_tag="PC465_001496"
     CDS             2471..3238
                     /locus_tag="PC465_001496"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HDF2648814.1"
                     /translation="MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLA
                     KKLDNIRKEEERLETINIFENEGYDKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTK
                     IEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
                     LKKAPDYLLVDAATIPGIDISQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYP
                     EYGFKSHKGYGTKEHYEAIEKYGITPIHRKSFLKNIL"
     gene            3296..4312
                     /locus_tag="PC465_001497"
     CDS             3296..4312
                     /locus_tag="PC465_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF2648815.1"
                     /translation="MEYNELLKSARENLNGSCKVCKVCNGVACAGEVPGMGGKGSGSS
                     FIENSKSLEKVKVNMRVIHDVSNPDTSIEMFGKKMSAPIFAAPVTGTTLNMGGKINER
                     DYIEPVVAGCANSGIYAMVGDTAVDAFLMENLDVVKKYNGAGIVFIKPWDNENIIKKI
                     RLAEEAGAFAVGVDIDACGLVTLSLHGKPVLPKNVKQIKELVKSTKLPFILKGIMTVE
                     DALMAVEAGVDAIVVSNHGGRVLDCTPGACEVLPKIADAVKGKVTILADGGVRTGLDV
                     LKMIGLGADAVLIGRPFVTASFGGATDGVETYVNKLQSELSSSMILTGCQTIKDIDGK
                     VIYK"
     gene            4378..4626
                     /locus_tag="PC465_001498"
     CDS             4378..4626
                     /locus_tag="PC465_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648816.1"
                     /translation="MSRKAYEEALVELEKFIDERKEIIKSAEDCIDKYIVDRTLPFDY
                     KDKCVEWQQELLDIAEAQVLEANELSVLLQEKKELEED"
     gene            complement(4802..5299)
                     /locus_tag="PC465_001499"
     CDS             complement(4802..5299)
                     /locus_tag="PC465_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HDF2648817.1"
                     /translation="MYKIGESVMYPKEGACSVNDIVTKKINHEMQKYYELSVIFNSNL
                     KISIPVLNADRIGIRPVMDGNDVDNFIQSINKTDGVWIFDRKERLKLYQDKFHSGDVF
                     EIVKLIKMLMIQDSSKQLCSTDKEFLNKAQKFALSELAAAQCKSYTMVLEEMKKHILN
                     SKNTN"
     gene            complement(5543..6607)
                     /locus_tag="PC465_001500"
     CDS             complement(5543..6607)
                     /locus_tag="PC465_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2648818.1"
                     /translation="MIRLTIANIKRYLKNHTLLINMVMLPIILIFSLNFFINNSGNQS
                     MYFSPVAIVFDSSGKYEHKLINSSKLKENSFRLNEQDKAMNLLKNNKVSAVFVLDKNF
                     SNSIDKLQRPVVKCFKIENGGGSLWAESQIESFITKSLKLKVDKNIDDKLTKTNIIDN
                     KPDKNKGSFLVVFLICYFMYINAAHLASDLFTLKKSNVLKRLISTDNKDIKIIFSIFL
                     GLFFIQSIVYTFALLCFSIIEDFNLSLNVLMIVLANSFVSTGFVFWVARVFKNESSIS
                     LISTFYSLIGLAISISSLIPSMDKLSFMTNLSKFTPFYWTIDAIKNNGSILINIIALI
                     LIGIIFVTAGSLKLRDFAKN"
     gene            complement(6610..7707)
                     /locus_tag="PC465_001501"
     CDS             complement(6610..7707)
                     /locus_tag="PC465_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2648819.1"
                     /translation="MKLYMSVKTMLKSLKSSFILNLIYFLALPLILSWFLGMVTESMF
                     QNPIKTESTPIVIYDKDNTRLSNDLTKYLKNDLSYILTVKKDDSKAELKLTIPKGYES
                     SLLNEKSNTLNIEKLGTRDDIAILLQDILDTYHEKFYLNNSQKISSEDFSKLFNKNSI
                     DTSIINNNVKQNSYEYFALVSLGFLVIIFIMNNILSNYISESKGLSKRLYSMPITRVQ
                     FLIYDFVGLWIYSFIFLLLYVLFFRILGITFKGNFAILLLLCALSSYFMTSISTFVTS
                     FFSKKYGTAIVYALLFLQTIFGGIFSMISDTFTKLTSLSPTYLIGELFSNYETFKTID
                     SIGDLIFTCLIISTILIALAIVKEKYKWREV"
     gene            complement(7721..8656)
                     /locus_tag="PC465_001502"
     CDS             complement(7721..8656)
                     /locus_tag="PC465_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2648820.1"
                     /translation="MDIVRVNNITKRFNDKLVLDNISFSVKKGEIFGLIGPNGAGKST
                     LINIITNLMLPNSGSIQINGLDLSKDYIKAKSIIGLVPQELAIIETLTPFDNLEYFGA
                     FYGLKGKLLKERIIEALEVTGLTEVKKKKVKKLSGGMQRRLNIGIALLNHPKILILDE
                     PTVGVDPQSRNHIFNFIKDISKKHETTVIYTSHYMEEVEHLCSKIFIMDEGKEIAFGD
                     NDYLKSLVSTNTKLIMEIKNINAQLIFDLKNTKGVISVLENNSLLELDIDKKLQLTDI
                     LSVIDKNNSKIMKISYEEPSLEDVFLNLTGKNLRD"
     gene            complement(8785..9432)
                     /locus_tag="PC465_001503"
     CDS             complement(8785..9432)
                     /locus_tag="PC465_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2648821.1"
                     /translation="MNKIKVLIVDDEKLIRKGLKIILSSYNDLEIVGDASNGYEALEF
                     CKMNDVDIVLMDIRMKVCDGVLGTRLIKEYNNSITLLILTTFNDDEYIKDAMKFGASG
                     YLLKDSSDEVLHEGIRSSFFGNIVLDKSVAEKIMTSEKTVKQEHLYDMYNLTEKEISI
                     IRLIANGLNNKEISQELFLSEGTIKNNITNILAKLELRDRTQLAIFAFKNKIVIE"
     gene            complement(9425..10588)
                     /locus_tag="PC465_001504"
     CDS             complement(9425..10588)
                     /locus_tag="PC465_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2648822.1"
                     /translation="MNREKLVAFIRYLSLFILVVSYLKNVENTLYPVITMIILFLIII
                     NNQVRFFSLSNENKFILISYFLELILIFILCNYTKTFNSIYFVPLILDISFLIKEKYK
                     YILFSFVIISSLIISLDKNIYLALESSSILLIITVLSIYIENENLSKLYSQNLYDKLR
                     ISKDELKKVNADLETYASSIEELAILKERNRISREIHDSVGHSLSTTIIQLNAIEKLL
                     KDKPLIYDLVHELREFVTESFQDVRRAISELKPVEYENYQSLFKIKELVKSFIKLTNI
                     NVKLTISKNTWNLSRNQSIALYRLIQESLSNSSRHGKATEIRIFITFNTSNLIITISD
                     NGIGCGNIKKGNGLNSINERIYELNGKVEFDNSNNGFTIRASFPKFSGGDFFE"
     gene            10772..11116
                     /locus_tag="PC465_001505"
     CDS             10772..11116
                     /locus_tag="PC465_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HDF2648823.1"
                     /translation="MNNKEKGDFGEKVAVNYLLSKGAKILEKNYRLKIGEIDIIAKME
                     DEIIFVEVKSRSNIKFGYPCESVSFKKRKKIIGVASYYIIKNNLNNTPIRFDVIEVYL
                     LEKRINHIMNAF"
     gene            11147..12748
                     /locus_tag="PC465_001506"
     CDS             11147..12748
                     /locus_tag="PC465_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HDF2648824.1"
                     /translation="MLSIINSSNLVGIDSFLVKVEVDVSNGIPSFNIVGLPGKEIKEA
                     RERVKSAILNSGYKFPSTRIVVNLSPADIKKEGAFLDLSISIGLLRELIKKDENYIRE
                     SMFIGELSLDGKIRKVRGILPIIMGAKTQNIKRIFIPIENIKESLFVDEIDIIPIKSL
                     KECVDFLNEEIKVDKVRIMSFLDDKSRKENEELEKDNSYIDCKYTKINNEESKYDEDF
                     KDVKGNYFVKRSAEIAAAGNHNMFMIGPPGSGKTMIAKRVRTILPDISVEEMIEVSKV
                     YSILGMINETKGIIDKRPFRAPHHTTTKQSLIGGGMDARPGEIALAHRGILFLDEIAE
                     FDRKILETLRQPIEDGYVNISRVKYSAKYPCRVLLVAAMNPCPCGYYMSETECRCRSN
                     EIDRYINKISGPLLDRFDIFVEVNSIKYSDFNSLKQEESSQKIKRRVENARKIQINRF
                     RKDNIKNNSEIKAYNLFKYCKLEKEASKTAEMIFNKYNLSSRSYTKLLKMARTIADLE
                     ERDLINSQCIIEAFSFRKAYYSYFK"
     gene            12767..13867
                     /gene="dprA"
                     /locus_tag="PC465_001507"
     CDS             12767..13867
                     /gene="dprA"
                     /locus_tag="PC465_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HDF2648825.1"
                     /translation="MEKRDTYLWLKSIGGITTKTIEIIENEIVNIEDIFDFSEKEIYN
                     LKNISLNIRKNIVKYRGHAYLENIKELLYKKAIKYICKYDKEYPENLKNIYNAPKLLF
                     YKGDIGLVNNNFNIAIVGSRKPTAYGINCAKTISCQLSQYGVNIVSGLAIGIDAYSHI
                     GCMSGKSKTIAVLGSGVDNPLPKQNLHLSNKILENGGLLLSEYNINSTVAPYHFSNRN
                     RIISGLSDGVVVVEAAIKSGALITVDFALEHGKNVFAIPGNINSQMSRGCHKIIKEGA
                     KLIENIDDILNEYNIFNIIDKKINQKYDNISLNAKSKQIIEAIKREGNLHIDSICDYT
                     GIEIKYVNSIINELVLNELVVEMNNKTYSLNV"
     gene            13900..15987
                     /gene="topA"
                     /locus_tag="PC465_001508"
     CDS             13900..15987
                     /gene="topA"
                     /locus_tag="PC465_001508"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HDF2648826.1"
                     /translation="MAKTLVIVESPAKAKTIEKFLGKSHYTVKASVGHVRDLPKSKLG
                     VDIENNFEPQYINIRGKGDVIKELKKEAKKSKQVYLATDPDREGEAISWHLAHILNLD
                     ESEDCRIEFNEITKDAIKKAIKHPRNIDINLVDAQQARRVLDRLLGYQISPILWQKVR
                     KGLSAGRVQSVTTKLICDREKEIKAFIPKEYWTIDVEAKTVKDKDITLKFYGKNDEKI
                     ELENEEAVNEILKEMEGKDLKVEKIESKSRRKSAPKPFTTSMLQQEGANKLFFTTKKT
                     MMIAQELYEGIDIEGEGTVGLISYIRTDSKRISDEAKEKAKGYIVNNLGENYYKNTGD
                     KKEKKDTKKVQDAHEAIRPTSVDRTPESIKASLSKDQYKLYNLIWRRFVASQMEDSVF
                     DILNVECKIGDIVFKATGSKMKFDGYTKVYNFSEREDKILPSIEKGDILNIENILPDQ
                     HFTQPPARYTEASLVKTLEELGIGRPSTYAPTIATILNREYVEKQGTSLCPTELGIIV
                     TDILENNFHKFIDVDFTADMESKLDVIEEGNTDWKKIVSESYAPLKEAIEEALENIEK
                     VNMDEETDEICENCGSNMVIKYGRFGKFMACKNYPDCKTTRPIMNKIGVKCPKCEEGD
                     IILRKSKRGKAFYGCSNYPNCDFVAWNKPTGEFCEKCGSYMVEKVTKSETKTVCSNKE
                     CNKETKEHNDGKE"
     gene            16152..16937
                     /gene="codY"
                     /locus_tag="PC465_001509"
     CDS             16152..16937
                     /gene="codY"
                     /locus_tag="PC465_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HDF2648827.1"
                     /translation="MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVV
                     SAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFP
                     EEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEILRAIG
                     EELEEEMRKKAVVQMAIGTLSYSELEAVEHIFAELDGKEGLLVASKIADRVGITRSVI
                     VNALRKFESAGVIESRSLGMKGTHIRILNDKLTDELKKLKNNQ"
     gene            17044..18309
                     /locus_tag="PC465_001510"
     CDS             17044..18309
                     /locus_tag="PC465_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HDF2648828.1"
                     /translation="MPLADKIRPKTMNDVIGQSHIIGNGKILSKILQSNFLPNMIFFG
                     PPGVGKTTVAEIIAERSNKSFYKINATNSSLEDIKKVISELGSINNVNGVLLYIDEIQ
                     SFNKKQQQSILEFMENGSITLIASTTENPYHYVYKALLSRSTVFEFKPLEKLDIEKGL
                     KRAVEVLNEDSYMDIECNNNAIEDIAILSDGDMRRALNILEVVVYSTKPNKDNITYID
                     SDVIRASTFNKIINYDKNGDSHYDILSAFQKSIRGSDPQASIHYLARLIKGGDLISIC
                     RRLLVIASEDIGLAYPNAIVIVKACVDSAMQLGFPEAKIPLAEATILLATSPKSNSAC
                     IAIMKAMDELDKEFVKDIPNSIKDAHYSGSKEIGRGCGYKYPHNFKNHYVKQQYLPDS
                     IKDSIYYIPQENKTEKNIKKYLEYLNGDF"
     gene            18340..19110
                     /locus_tag="PC465_001511"
     CDS             18340..19110
                     /locus_tag="PC465_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2648829.1"
                     /translation="MIIKLNSTYHSRVMKYLKKEPEYNLFIIGDIERYGYGNNFLNIW
                     ADVGEHGEIKAILLKYFEFMMFYSDGEYDVEGFYNLLRNTNYEEISGKICAVDALAKR
                     LGLNNLKVVDFCKLQTKKFLIDNNCNVKVKRIRLGNLKKTVKLYDLIDEFHSTTLENL
                     KNGLRTGRGYCIEINKQVVSMAKSTSENRTHAMIIGVGTHPKYRAKGLATKCLIKLCS
                     ELLRENKIPCLFYDNEEAGKIYKKLGFENIGKWGIYSK"
     gene            19219..19665
                     /locus_tag="PC465_001512"
     CDS             19219..19665
                     /locus_tag="PC465_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDF2648830.1"
                     /translation="MKLSTKGRYGLKAMFELALNQDNGPVSLKFIAKKQKISDQYLEQ
                     IFSSLKKSGLVKSVRGAQGGYLLSKNAEDITVGDILVVLEGPVALSDCVLDEDVCENS
                     NMCVTKIVWEKMKKGIEDVIDSITLKDMINDYNKNKLENDITNIKK"
     gene            19683..20876
                     /gene="nifS"
                     /locus_tag="PC465_001513"
     CDS             19683..20876
                     /gene="nifS"
                     /locus_tag="PC465_001513"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase NifS"
                     /protein_id="HDF2648831.1"
                     /translation="MEKRRLYMDYSATTPIKKEVLDAMMPYLTDYFGNASSFHTFGRE
                     AKDALDKAREQVAALINAEPSEIYFTAGGSESDNWTLEGVAYANKNKGNHIITSKIEH
                     HAILHTCEYLAKHHGFEITYLDVDSEGKVDLKQLEESIKDTTILISIMFANNEIGTIQ
                     PIKEISEIAKKHKILFHTDAVQATGNIPVDVKELGIDLMSMSSHKIYGPKGVGALYIR
                     KGVRLHNFVHGGAQEKSKRAGTENIPAIVGYGKAAELAKENMQNHVETLTRLRNKLID
                     GVLERIPYTRVNGSLENRLPGNANFAFQFIEGEGILLLLDMLGIAGSSGSACTSGSLD
                     PSHVLLAIGLPHEIAHGSLRLTVGDFTTDDDIDYILENLPKVIERLRSMSPLYDDAKK
                     QGLVK"
     gene            20930..21370
                     /gene="nifU"
                     /locus_tag="PC465_001514"
     CDS             20930..21370
                     /gene="nifU"
                     /locus_tag="PC465_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold protein NifU"
                     /protein_id="HDF2648832.1"
                     /translation="MQYSDKVMEHFMNPRNMGEIDNASGVGEVGNPTCGDIMKIFLDI
                     DGDVIKDVKFKTFGCGSAIASSSMATEMIKGKTIKDALELTNKAVAEALDGLPPVKMH
                     CSVLAEQAVKAALIDYAQKNNIHIPELDGYVIDDAHDHDVEEEE"
     gene            21659..22738
                     /gene="mnmA"
                     /locus_tag="PC465_001515"
     CDS             21659..22738
                     /gene="mnmA"
                     /locus_tag="PC465_001515"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HDF2648833.1"
                     /translation="MNKKVMIGMSGGVDSSVAAYLLKQQGYDVIGVTMKLWQDDDVVE
                     IEGGCCSLSAVEDARRVANKIGIPFYVLNFREVFKEKVIDYFIDEYLEGKTPNPCIAC
                     NKHIKFDDFYKKARQIGCDYVATGHYAKIEKDESTGRYLLKKSVTDKKDQTYALYNLT
                     QEQLEHTLLPIGDYEKDRVREIAKEMGMAVHNKPDSQEICFVKDNDYANYVKKHSKKR
                     IEEGFFVDTKGNILGKHKGILYYTIGQRKGLGITFGKPMFVIDINPINNTIVLGDNED
                     LFKKELIAKNVNFISIDTLEEPLRVQAKIRYSAKPSPATIHRVGEDTIKIVFDEAQRA
                     ITKGQSVVMYDGDIVVGGGIIEKSL"
     misc_binding    22881..23119
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            23187..25826
                     /gene="alaS"
                     /locus_tag="PC465_001516"
     CDS             23187..25826
                     /gene="alaS"
                     /locus_tag="PC465_001516"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HDF2648834.1"
                     /translation="MEKMGLNEIRSKFLEFFESKGHYVANSYSLVPNNDKSLLLINSG
                     MAPLKNYFSGVEVPPSVRMCTSQKCIRTGDIENVGITARHATFFEMMGNFSFGDYFKR
                     ESIKWGWEFVTEWLNIPEDKIWVTVYEEDDDSYDIWAKEMNFPEERMVRLGKDDNFWE
                     IGTGPCGPCSEIYFDRGEEYGCDNPDCKPGCDCDRYLEFWNHVFTQFDRDEEGNYSLL
                     ENKNIDTGMGLERMGCIMQGVDTIFEVDTIKSILEAVEKLTGVKYGENPKNDISIRII
                     TDHIRAVTFLVSDGVLPSNEGRGYVLRRLLRRAARHGKLLGVKELFLQKLIDEVIKVN
                     DKAYPVLVEKESYIKKVVGIEEEKFNETIDQGTEILNSYIEVLKNEGKTVLSGQEAFK
                     LYDTYGFPIDLTKEILEEEHLSVDEEAFNEEMEKQKERARNARGNMDGESWKEDPLSK
                     LESTVDSTFNGYSEIYGEGTIEAIVKDDELVQSAEEGDKVSIVLDNTTFYPEGGGQVG
                     DCGLITNENLVLEVLNTKKGANNSIKHIGIIKSGRISNGDKVKTLVDRETRMSAARNH
                     SATHLLHKALREVLGEHVNQAGSLVTPERLRFDITHFEAISNEELKVIEEKVNNVILS
                     SLDIKCDIMNIKEAKEKGATALFGEKYGDEVRVVSMGDYSTELCGGTHLTNTSQVGMF
                     KILSEGGVAAGVRRIEAITGKAVYEYLKERDGIISEVCVNLKSKEDNLIQRISSLLEE
                     NKNLSKELHDMKAKMSLQSVDSIFDSKVEVNGVNLITNKFEGMDMDTLRETADNLRDK
                     LGSGVVVLANVVDDKVNFVVTATKDVLDKGIHSGNIVREVAKIAGGKGGGRPNMAQAG
                     ASDVSKVDQALSYASEVIKTQVK"
     gene            25851..26108
                     /locus_tag="PC465_001517"
     CDS             25851..26108
                     /locus_tag="PC465_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HDF2648835.1"
                     /translation="MEKDLDYTMKFEGIPEDRMSVGDTIDFVYKALVEKGYNPINQII
                     GYLLSGDSSYITSHKNARAIIKKFERDEILEEVITHYLNRK"
     gene            26118..28289
                     /locus_tag="PC465_001518"
     CDS             26118..28289
                     /locus_tag="PC465_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648836.1"
                     /translation="MRKKIMSLFAIVIMIFVSTASYGFAEEKGKVIFIDMNRTNLGSM
                     MNIPILKNEIEKRGYVALMNIRGDQGTDDRRSYASMGAGTRASVTTEDYINFQKVDQD
                     TAKAFEVATGQKAKEINDLGINRSINENLEYGEYGANLGSLGKTLSENGLKTSVIGNA
                     DIIENNQLVKNRNLCLVAMDQYGRIDSGNIDNINKKDSKMPFGISTDYDKLLDETKKS
                     YKNSDAIFVELGDTYRLDMYRLNLNDNTYDTMKKNIVKNINKYLEQVFSMVGENDTVY
                     IASAFPSDLDYKNKRRLSPIIKFSGEGKGLLESATTRKAGIVANLDVGVDILGTFGLE
                     NKEMVGRSYTLVNKEDNISYLKSLYERIVSISSIRSTIINGFVGVISASWVIAMFAIF
                     FRNYMPHKERVFKVLKEFIKLGIIMPLSFMLAPLMNFKTPISISLGIFATTLILYLLG
                     RKLFKDNDIKHMGFFATLTILVIVIDSVFGTYLMQNNIMSYDAVIGARYYGVGNEYEG
                     VTIASAVFGLAVLLHYKKVSKLLVVIFSLIILITSAYPSMGANVGGAISECVAYLLFI
                     MLIYDIKIDFKKAVLLAVSAVVVVFAFAALDILSGSESHLGMFVQRIFLNGPGEILQT
                     FGRKIQMNMQLAQTSVWVNILLVGIGVIAVLIFKPSRHFRKIMNNFPILFKGFIASMV
                     GCIITLLVNDSGIVAASTASIYILIPLIIISINMIIFEKNN"
     gene            28495..28920
                     /gene="ruvX"
                     /locus_tag="PC465_001519"
     CDS             28495..28920
                     /gene="ruvX"
                     /locus_tag="PC465_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HDF2648837.1"
                     /translation="MLDGRIMGLDVGDKTIGVAVSDLMGLTAQGVKTIKRVGKKKDIE
                     ELKAIIKEKQVNKIVSGLPKNMNGTLGPQGEKVIKFCELVKAETGIDVEFWDERLSTV
                     AAERSLLEADVSRQKRKKVIDMLAAVIILQGYLDFKINS"
     gene            28998..29285
                     /locus_tag="PC465_001520"
     CDS             28998..29285
                     /locus_tag="PC465_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HDF2648838.1"
                     /translation="MEENIINLIDENGVESQFEIILTLEAEGKEYAILMPLDDEEAEE
                     ALIFRIDEDEEGEILIPLESDEEYETVVAVYTAIMEEEGLNYDEDESNGLN"
     gene            29567..30025
                     /locus_tag="PC465_001521"
     CDS             29567..30025
                     /locus_tag="PC465_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDF2648839.1"
                     /translation="MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIY
                     DLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICK
                     NCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE"
     gene            complement(30142..30879)
                     /locus_tag="PC465_001522"
     CDS             complement(30142..30879)
                     /locus_tag="PC465_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDF2648840.1"
                     /translation="MRGKTHCAIGILTAIQTSLIFKIPISLVDILVSATFAVLPDLDK
                     SNSMVSNFILKNNVSKYIYRIFIYAVNIIIFFISININDNFYLSAIITFVAIIIIEAK
                     LTHTFLRKVFLSLIFILLAICLYIIEVEIYFTIFCLMLSIFPWLKHRSFSHSIFATII
                     VYFLLKQIELITNINNLSFYGTIGYASHMFLGDLFTKQGIPIFYPLSEKKISLGFLTV
                     GGPFSNFIEKSFIFVLIGLIIFSILKL"
     gene            31096..32772
                     /locus_tag="PC465_001523"
     CDS             31096..32772
                     /locus_tag="PC465_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HDF2648841.1"
                     /translation="MQLFKKNTNKIKVMALGGLNEVGKNMTVVEYKDEIIVIDAGLSF
                     PEDEMLGVDIVIPDITYLVKNRDKIKGIFITHGHEDHIGALPYILKKINVPVYGARLS
                     IGLIQVKLKEHKMNNVKLNVIGPRQVIKLDNMEVEFLKNNHSIPDAYSIAIHTDQGII
                     YHTGDFKIDLTPIDGDVMDMHRICELSKKGVLLMLADSTNAEKPGFTMSEKTVGVGLD
                     ELFAKGNGRRIIVATFASNIHRLQQIINTAEKFNRKVAISGRSMVNVVGVAKELGYLD
                     ISDDMLIDLNDICKYEDSELVIITTGSQGEPMSALARMAFSEHKKVEIKSGDLVIISA
                     HPIPGNEKLISRVINFLFEKGAEVVYSDIADIHVSGHACQEELKLIHALVRPKFFMPA
                     HGEYRMLKRHAEIAEQLGMDKENIFVMQTGDVLELDKNSAKVANRIQTGNILVDGLGV
                     GDVGNIVLRDRKHLSEDGLMIVVVTISKDEGKVLAGPDIISRGFVYVRESEDLMDGAK
                     DIIKNVLNECEEKNIKEWAYLKNNIKENLKEYLYQKTKRNPMILPIIMEV"
     gene            32978..33178
                     /locus_tag="PC465_001524"
     CDS             32978..33178
                     /locus_tag="PC465_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protein"
                     /protein_id="HDF2648842.1"
                     /translation="MDDVSRQNAIKALKQTKMEIAGEYGMNYEDAFEIIENASNKGVL
                     EGYFKKLEKKKNLGQGISRHLE"
     gene            33232..34395
                     /locus_tag="PC465_001525"
     CDS             33232..34395
                     /locus_tag="PC465_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF2648843.1"
                     /translation="MKKLASTALAILIALTPLSFSFANNKENADANQLNISSKSAILM
                     DVGSGQILYEKDAHKKLPPASVTKVMTMLLIVEALDSGKIKLDDEVQVSETASSMGGS
                     QIFLEPGETQKVDTLLKGIAVASANDACVAMAEHLAGSVEGFVDRMNAKAKELNMNDT
                     HFANTNGLPVANHYTSAHDIALMSRELLKHEMISKYLTTWMDKVVVGKKQVTVGLANT
                     NKLIKHYQGATGVKTGFTQEAKYCLSASAKRGNTHLVAATLGAETSPERFNDASSLLN
                     YGFANYESVKLCSKGDNIATLTLDKADENKVKLVAKEDLNTLIKKGSSKEFEKKIEIV
                     KNPKMPIKKGTVLGKIKICKDKKVIGEVELINTKDINKASYLQMLQRIIDNMI"
     gene            complement(34606..35028)
                     /locus_tag="PC465_001526"
     CDS             complement(34606..35028)
                     /locus_tag="PC465_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2000 domain-containing protein"
                     /protein_id="HDF2648844.1"
                     /translation="MENKNSKCVMVIDENLPMGIISNTAAIMGITLGKHAPETVGPDV
                     IDKTGNSHLGIIDIPVPILKGNKEIIKDLRKKLYTLEFNDLTVVDFSDVAQSCNLYEE
                     FTQKIASVPEDELQYFGIAIYGNKKKVNKLTGSMPLLR"
     gene            complement(35049..35885)
                     /locus_tag="PC465_001527"
     CDS             complement(35049..35885)
                     /locus_tag="PC465_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2648845.1"
                     /translation="MRQEERTVCFDRELKIEAYRFKGIMQKFPNHFHEHYVIGFIEKG
                     QRYLSCKNKEYTTSTGDLLLFNPFDSHTCEQIDDKVLDYRCINIKPEIMKKTVFEITG
                     KNYLPKFNQPVIFRSELVPLLQELHYIIMEEELDFKKEELFFFLIEQLIEEHTEPNLQ
                     SNLENTNIEIQAVCDYLENNYAEHIVLDELSTIAGMNKYSLLRNFTKLKGITPYRYLE
                     NIRVNKAKKLLEKGVEPIDAAIQTGFVDQSHFTNFFKNFIGLTPKQYQNIFINDDSNN
                     FK"
     gene            36183..36779
                     /locus_tag="PC465_001528"
     CDS             36183..36779
                     /locus_tag="PC465_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HDF2648846.1"
                     /translation="MLSMNIGEIVASLVGIAMAISIHEFGHAYSAHLLGDDTAKAYGR
                     MTLNPVRHVDPIGLLAMFILKIGWAKPVPVNPNNFKNYKIGNLIVSLAGVFCNVLTAI
                     LCVIINKYVHMYAINTIAGYVLLYSMGFAAFNLLPIPPLDGWGVISTFVPYKWNEYLY
                     KFESMSYIILLIALFTGIYQIILSPIYTVLLKIVYLFV"
     gene            36809..37528
                     /locus_tag="PC465_001529"
     CDS             36809..37528
                     /locus_tag="PC465_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HDF2648847.1"
                     /translation="MKYNIQLQVYEGPLDLLYDLITKHKIDIKDISIIDITKQYLNYL
                     KMLDKMDLEITSEFITMASKLLEIKSKYLLYKQKDEEEDPRIELMEKLEEYRKFKVAS
                     QDIKENITYVNERFYRNKEEIIIDDNVDLEDISIEAIKNILPYIFKVKTSQIENANDE
                     KLDKIVRKKIISVEEKILYIRDIIKDKIEVTFTNIIKSYENDEIIATFLSILELIKEK
                     EIVVVQDIFFDDILIRKSSEC"
     gene            37530..38069
                     /gene="scpB"
                     /locus_tag="PC465_001530"
     CDS             37530..38069
                     /gene="scpB"
                     /locus_tag="PC465_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HDF2648848.1"
                     /translation="MKREDIKYIIESVMFAYGEPISIKELNYIINKELSSKEIEIMLN
                     LLIEEYREQNRGIQIIKLENKYQMCTNKDYAEYIKKIIEPKKKKSLSQATLETLTIIA
                     YKQPITKVEIEDIRGVKCDKVLQTLFENKLIREAGRLNKIGKPIIYKTTDEFLKLLNI
                     ESLEELPPIENYQEVATNE"
     gene            38231..38860
                     /locus_tag="PC465_001531"
     CDS             38231..38860
                     /locus_tag="PC465_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2953 domain-containing protein"
                     /protein_id="HDF2648849.1"
                     /translation="MELNELFNFKYLIIAVIFIISVTMLILISHINILIIADIKNKDI
                     CLKLNIKYMFNLININRQLYPAENSKNNDKKEGMKNNIDSSILLADDLLSIYRLLKKI
                     KIHELYSNINFGTGNIGLTSSVYVLINTLYGNLFNMIDAEKMYLNVNPDFTKDYVLGN
                     IRIHIRPRIKALFNIIIMINKIMNKNKGNKEGDSNESNRFDTESYGNNS"
     gene            38814..39242
                     /gene="ytfJ"
                     /locus_tag="PC465_001532"
     CDS             38814..39242
                     /gene="ytfJ"
                     /locus_tag="PC465_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerW family sporulation protein"
                     /protein_id="HDF2648850.1"
                     /translation="MRATGSIQSLMETTLETIKGSIDANTIIGDPIKTDTTVVVPISK
                     VTIGFGIGGGEYSKGYDDKDREIELKNEKSDTNFAGGSAGAISVQPVAFVVVESGETR
                     IMSLDSNINLVDNILSITPRVLEKIQNISQSNKNQDKNNM"
     gene            39490..39930
                     /locus_tag="PC465_001533"
     CDS             39490..39930
                     /locus_tag="PC465_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2648851.1"
                     /translation="MSDKELSILLLESMNNFHNLIKIINNERYKKDKVLTERQFFALV
                     KIRKHDKIELKNLSRDLHVSTSSLCILLNKLVEQEYVYREEDSRDRRNTFYGITKNGE
                     KILDNEILKFVSIISDKMDCLDIDNKDKLFTSLEESKNIIEQLF"
     gene            39946..41397
                     /locus_tag="PC465_001534"
     CDS             39946..41397
                     /locus_tag="PC465_001534"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HDF2648852.1"
                     /translation="MNIKYSKEILKSLENAITVVALFEGEDVFTTFDKINMISRNFNS
                     KENSIDTVTLIENNNLVNVCFVGFGKRELLNREKIRIIGGNLCKKLKNILKNEAYKSS
                     DVNVLNLNLNSDEIGCFVEGILLGNYKFDKYKTKSKDFERKEVDTITIFTEKEVECQI
                     EKAKILANSTIIARNLVNEPSNVIYPKTLAVETVKLGAEFGFNVDVYEEEKIKALGMD
                     AFFAVSRGSINKPRFIVMRYFGDKESTDILGLVGKGLTYDTGGYSLKSNASMLDMKTD
                     MAGAASVIGAMCAISQSKLKKNVIAVVAACENALSGGSYKPGDIISSMAKKTIEVLNT
                     DAEGRLTLADAIYYIINNEKVTKVVDVATLTGAALTLLGNVATPIVTNNDDFYCELEK
                     AATLSGERVWKMPIYDEFKDMIKGEEADLKNTGGKNAGCITAGAFIGEFVGNTPWIHM
                     DIAGTSTSSKSIGYKAKGATGEPVRTLYYLAEI"
     gene            complement(41488..42156)
                     /locus_tag="PC465_001535"
     CDS             complement(41488..42156)
                     /locus_tag="PC465_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwaF family protein"
                     /protein_id="HDF2648853.1"
                     /translation="MFKIFLFSSEQFVSLFIFGLFLYYCPKLTKNILPYSYTVEKIIC
                     TLLVIIMALEQLLLISSGNYSTLNSLPIGINYICIYLCIAILIFKQYHLFNIFFSWSL
                     VCSVGELIFSKNLGYEFPSLIYFIFIFSKCLIIYADIYMVDVRKFRVNRYALRDNLAI
                     CFIYFSFIFLLNTFTNSRYYYGFLSHSITAIFTFIFVTSIMYIPALLFNRDTFILEKK
                     KKSK"
     gene            42425..42565
                     /locus_tag="PC465_001536"
     CDS             42425..42565
                     /locus_tag="PC465_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648854.1"
                     /translation="MGIIESASKLAEMVHLLAVEKGITDIEAWDEAVKEYSKIYEERR
                     NE"
     gene            complement(42740..43060)
                     /locus_tag="PC465_001537"
     CDS             complement(42740..43060)
                     /locus_tag="PC465_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HDF2648855.1"
                     /translation="MKLKTISLPELNNLDPTLESTFIKMGEEQGELAECIGKFRNLSG
                     ENNDLDEVDIIKKTAKELMDVAQTCVTMMFKLEEQYGINLDEIRKEHIKKLEKRGYIK
                     NMDK"
     gene            complement(43180..43917)
                     /locus_tag="PC465_001538"
     CDS             complement(43180..43917)
                     /locus_tag="PC465_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HDF2648856.1"
                     /translation="MDANSLKDLIANHNNIVFFGGAGVSTESNIPDFRSSTGLFSQKL
                     NKQFTAEQLVSHTFFVRYPEEFFEFYKDKLIYPNAKPNNAHIALAKLEEMGKLKAVIT
                     QNIDGLHQMAGSKNVLELHGSVHRNYCTKCGKFFDLESMLNLGGNIPYCDNCGSIVKP
                     DVVLYEEALDSDVITKTISAISNADLLIIGGTSLAVYPAASFIDYYKGDYIALINKAN
                     TVYDKSASLVINKPIGEVLYEAVLRQI"
     gene            44132..45955
                     /gene="acd"
                     /locus_tag="PC465_001539"
     CDS             44132..45955
                     /gene="acd"
                     /locus_tag="PC465_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HDF2648857.1"
                     /translation="MKKKAALATLAMLPLGVVNAHADGDIGIVTINYLNVRNEPTAES
                     SIAFVAKKDDKVLIKDSSNGWYKIKAESGQEGWASSKYIAKSNSDSLRTSTNKEKQVI
                     SNSLNMRNGAGTSYRVITVLKKGQKVEVISESNGWSKIKYDGRLGYVSSSYLGDVSNS
                     TNKSKTKQVNTTSLNVRSGPNTSYGLLGKLPKGSKVEVISESNGWSKIKYNGKDAYVS
                     SMYLSDVSQSNSDNSSQSNDKKNTDKVVNTASLNVRSGPGSTYSKLGKVYKGSKVTVL
                     SESSGWAKINFNNKEAFVVGNYLSTSADTSNNNSNSNSDNSSNSNGNNSSSSGQVNGM
                     SGISGAKIDYKSLSYTLESHISKQVEKAASGGNVIAPSNRKSTPSPEFSTFSAQRTSS
                     FVNASSSDIEYYLNPKNFTNTTKGMMQFLKINSYRDGISESSLNSYLNGLSSSVFKNQ
                     GAAFINAAKKYNIDVVYLVSHAMWETAYGKSTLAQGQTLTSYKGQPLSKPVKVYNFFG
                     IGAIDKSANVSGAEAAYSNGWTSVEATIDGSAKWISQNYVNSSKYNQNTIYKMKWNYD
                     YTWHQYATDVNWANGISGIMENLIGLYGGGSSLVFEVPQYK"
     gene            46170..50468
                     /locus_tag="PC465_001540"
     CDS             46170..50468
                     /locus_tag="PC465_001540"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HDF2648858.1"
                     /translation="MESIKEYLDKLEINNSGLGKQLKEVYINRVVYFKEDKIVYFYLT
                     SKDIVSHELLDKFKEELMYKLDYFKDMRMKIRFTGLERKSNKDVIKKYWNNILYILKY
                     LCPSIAGWYKQVEFLCLEEELKIKLPKGIFYERLMKKNVTYVLKTVLSEELGLDLNIT
                     IEKAVDEKVNKERLIRINDREMEEKIRALEIGKVNNCEENEEESYVIKSDVDENLIYG
                     DNANAMIENIVELNASSGTVAVVGDIFDVDTKELKNGKILMIASITDYTSSISCKLFL
                     TDTNKDGVLENVKKGAYLKIKGDIVYDTYQREISMMISGIRKETRIEREDKSEEKRVE
                     LHAHTQMSSMDAICSVKKLVERAAKWGHSAIAITDHGVVQGFPDAMNAGKSNNIKILY
                     GVEGYLVEDDSLIIEDANDKELSQTFVVFDIETTGFSNTNDKITEIGAVKIENFKIVD
                     RFSELINPEKDISYKIQELTGITNELIKDKPTIEEVLPKFMEFVGDSVLVAHNAEFDT
                     GFISQKCREQGLLYNNKKVDTLMLARVMLPNLKRHRLNVVAKELGIPLLNHHRAVDDA
                     EATALIFNKFLQMLTEKGAKTLSDVNNILGKIDYTKLSTNHITLIAKNSIGIKNLYKI
                     ISDAHVNHFFRAPRILRSVLNEYKEGLIIGSACEAGVVFQAVKKNVSDEEMKKIIDLY
                     DYIEVMPIDNNRFMIDKGEVKDEEELRELNRKLIDTAKKFDKIPVATGDVHFLDKHEA
                     VLRKVLKYSQGFKVDEEETYLHFRTTDEMLEEFSYLGEELAYEVVVENSNLIADMVED
                     IKPIPDDTYPPIIEGSDVELREMCYKKAKRIYGDPIPEIVQKRLDRELNSIISNGYAV
                     MYIIAQKLVAKSLSDGYLVGSRGSVGSSFAATMSDITEVNPLPAHYICENEDCKYSFF
                     YEIGEWGSGVDLPDKDCPKCGRKLAKNGHDIPFEVFLGFEGDKEPDIDLNFSGNYQPT
                     IHKYTEELFGEGYVYRAGTIGTVAEKTAFGYARKYVEENNISVPNAEVLRLSNGCTGV
                     KRTSGQHPGGVMVIPDYKDVYDFTPIQYPANDTSCGVITTHFDYHSISGRILKLDILG
                     HDGPTIIRMLEDMTGINITEIPLDDKETMSLFTSTEALGVTPEEINCPIGCLAVPEFG
                     TKFVRQMLLDTKPTTFAELVRISGLSHGTDVWVNNAQDLVREDIVGLKDVISTRDDIM
                     NYLIFKGLPPKMSFTIMESVRKGKGLKPEHIEEMKKNNVPEWYIGSCKKIKYMFPKAH
                     AVAYVMTSFRIAYCKVHYPEAFYATYFTTKVEDFDADLIVKGLDAIKSKINEIESLGN
                     DATTKEKGMLTVLEVALEMYARGIKLLPVDIYKSDATEFIVVGEKTLLPPMAAIQGLG
                     GNAAINIQNERKNGEFISKEDLRKRTKISKTVIETLTNHGSLENMSERNQLSLF"
     gene            50672..51133
                     /locus_tag="PC465_001541"
     CDS             50672..51133
                     /locus_tag="PC465_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HDF2648859.1"
                     /translation="MKKNLEATIEEIVTKITDEHGFEMVDVEYVKEAGEYYLRVYIDK
                     EEGISLNECELVSRELSPILDEKDPIKENYFLEVSSPGLDRALKKDRDFVRYQGRDVD
                     LKLYKPLNGCKQFEGELVGLTEDNNIKIIANGKEMEFNRKDVAIVRLAIKF"
     gene            51163..52317
                     /gene="nusA"
                     /locus_tag="PC465_001542"
     CDS             51163..52317
                     /gene="nusA"
                     /locus_tag="PC465_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HDF2648860.1"
                     /translation="MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQN
                     VRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPK
                     NFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
                     GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIY
                     EGIVQIKSVAREAGSRTKMAVRSIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIK
                     YSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTN
                     WKIDIKSESQAEQEMLNLENSKEIEAEDVEAEFIDQEELDTSEDNFSEEE"
     gene            52324..52605
                     /locus_tag="PC465_001543"
     CDS             52324..52605
                     /locus_tag="PC465_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HDF2648861.1"
                     /translation="MILKKVKKVPQRKCIACQDRDSKKELIRIVKNKEGKIFLDPTGR
                     ANGRGAYVCKSSECLKKAIKSKALNKAFKIDVPDEVYDNLLMELEEYEK"
     gene            52595..52906
                     /locus_tag="PC465_001544"
     CDS             52595..52906
                     /locus_tag="PC465_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal L7Ae/L30e/S12e/Gadd45 family protein"
                     /protein_id="HDF2648862.1"
                     /translation="MKNNKEKVLSFLGLATRAGKIVSGDDSTLLDLKKGKVNLILIAE
                     DASNNTKKLFKDKSTFRNIPYLFFSTKEEIGFAIGKSPRAVVGIKDENFSKKIIELIE
                     I"
     gene            52928..54868
                     /gene="infB"
                     /locus_tag="PC465_001545"
     CDS             52928..54868
                     /gene="infB"
                     /locus_tag="PC465_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HDF2648863.1"
                     /translation="MSKTRVYQIAEELNISNEELINKLAELDINVTDKDSVLEGEELE
                     LALEMLGEDLSQENGNVIEIDGKLTVQVLATKLDKSPSEIIMKLMKMGTMATINQEIS
                     FEIAALAAKDYGFELTVAESDDTEALEIEALMEIEEDKEEDLKPRPPVVTVMGHVDHG
                     KTSLLDAIRKTDVISGEAGGITQHIGASEVKINGHKIVFLDTPGHEAFTSMRARGAQV
                     TDIAILVVAADDGIMPQTVEAINHAKAAGVPLIVAINKIDKPGANPDKVKQELADQGL
                     LVEDWGGEVIAVPVSAKKKEGIDTLLEMVLLVAEMEELRANPNKRAVGTVIEAELDKG
                     RGPVATVLVQGGTLTVGDPIVAGVACGKVRAMINAKGKRVKTAGPSTAVEILGLSEVP
                     QGGDQFVEVPTDKIARSVAARRQQIVRDEMLKSTQRLSLDALFSQMSEGSIKDLNIVI
                     KADVQGSVQAVKQSLEKLSNEEVQVKVIHGGVGAVTESDILLAAASNAIIIGFNVRPV
                     PGAESLGEKENVDIRTYTIIYKAIEDIQAAMTGMLDPEYVDEETGKAEIREIYKISGV
                     GTVAGCYVTNGKIFRNCKVRLVRDSIIIHEGELAALKRFKDDVKEVNSGYECGMSFVN
                     YNDIKEGDIVEAYITKEVERKL"
     gene            54911..55291
                     /gene="rbfA"
                     /locus_tag="PC465_001546"
     CDS             54911..55291
                     /gene="rbfA"
                     /locus_tag="PC465_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HDF2648864.1"
                     /translation="MASYNRTRRIAEEIRKVVSTMLINGVKDPRITSMVSVTDVEVTN
                     DLRYAYVYVSILGGDEESTLTGLKSAGGYIRREVGKNIKLRYIPEIVFKLDDSIEKGM
                     YMDSLIKRVNEKNAQQNEDENYDE"
     gene            55272..55949
                     /locus_tag="PC465_001547"
                     /pseudo
     CDS             55272..55949
                     /locus_tag="PC465_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
BASE COUNT        22469 a         6020 c         9857 g        17695 t
ORIGIN      
        1 cttttatata cttttttata ttatttttga gttttttagg aagatatttt acaagttaag
       61 aaaactataa ggagtgttat attgaatata aaatagtata atatatatta tgttagataa
      121 ttaatatgaa aatatacaaa tatataaaaa gtttgtttag agttatagtt aatgtgtgta
      181 ttaatttaat actaatttat tggaggttta aaaatgaagt acataataaa aagagatggt
      241 acaaaagaac tttttagtaa aagtaagatt gaagatgctg tctataaagc tagtataaat
      301 agtgaaggtg gcgtagatag agagttggca tatgatatat caagaaaaat agctaatgac
      361 tataattcta tggaaaaatg cttatccgta gaagaaatac aagatatagt tgaagtacta
      421 cttatggaat caaatagaaa agatatagca aaacactaca tattatatag agaaagacgc
      481 tctgaaataa ggactaaagc ttgggagttt gatgaattac aaaaatcaat atggaagaac
      541 aagtatagac ataatggtga gagttttgat gaatggataa agagaatttc aaataatagt
      601 tcaagaatat caaaactaat aagacaaaaa agatttctat ttgctggaag aattttagca
      661 aatagaggat tacagaaaga gggaaaaaaa gtaacatatt ctaattgtta tgtaatagaa
      721 ccaccaaaag atagcataga agatatattt gatactgcaa aaaaacttgc tagaactttt
      781 agttatggtg gaggagttgg aattgatatt tcaaagctaa gaccaaaagg agcgaaagtt
      841 aacaatgctg caaaacatac gactggagca gtctctttta tggaacttta cagtatgaca
      901 actggcttaa ttggtcaaag agggagaaga ggagctctta tgatttctat ggatgtaaat
      961 catccagaga tagaagactt tatagatata aaaacagatt tggagaaggt tactaaagca
     1021 aatatttctg taagagtaac agatgaattt atgcaagctg taagagaaaa aaagttatat
     1081 aattgtactt ttgaagttga aactactgga gaaaaaatag ttaagatagt aaatgcttat
     1141 gatttattta ataaatttgt gaaaaataac tgggattatg cagaaccagg tatattgttt
     1201 tgggataaaa taaaaacata taattttatg agtgaagata agaacttttg cttttcagga
     1261 gtaaatcctt gtgcagaaga accacttcca agtggaggaa gttgtctact tggctcaata
     1321 aacttgtcag agtttataat acaaccattt ggtgaacatg ctacttttga tattaataaa
     1381 ttaaaatctt gcgttagaga agctgtagta gctttaaatg atgtcttaga tgagggattg
     1441 aacttgcatc cattacaaga acaaagagat agtgtacata agtatagaca gataggttta
     1501 ggtgtaatgg gtatagctga tatgcttata aaaatgggaa taagatatgg ttctgatgaa
     1561 tctttagaac tatgtgattt aattggtaag actatgttaa atgaagctgt gaagcaatca
     1621 gcattaattg ctaaagaata tggaacattt agtgagtata aatatgaaaa tatttctaaa
     1681 tctaagtttt ttatagaaaa tctaaatgaa gacactaagg aaatggttaa aaagtatggg
     1741 cttagaaatt cacaactttt aaccatacct cctacaggtt ccatatctac aatgataggt
     1801 atcagtggtg gaatagaacc tatatttaat ctttcatata taagaaaaac tgaaagcttg
     1861 catgatgagg atgtgtatta taaagtatat actccaattg ttaaagagta tatggacaag
     1921 aaaggtatta cagatgaaga atgtttacca gatttttttg ttactgctat gaatatagga
     1981 tatgaagaaa gaataaacat gcaaaaagta tggcaaaagt atattgatgc ttctatatca
     2041 tctacaataa atataccttt tgaaactaca gttgaagatg ttttcaatat atatattaag
     2101 gcatgggagg ctggtcttaa aggagtaaca atatttagag atggatgtaa aaggagtgga
     2161 attttaataa atgaaaaaaa ggaagaaaat aataaagaag ataaaaaaga aaatagtaaa
     2221 aaagaatatt ataaaaataa taaaaaagaa aaagataata aagatgaaaa agccaaagaa
     2281 ataataaata aaaattttga agaagatgaa aaatttgtgt gccctgagtg tggaagtgaa
     2341 ggaattgcac atacaggtgg atgtagtata tgtttaaaat gtggctatag tggatgcaat
     2401 taaactctaa ttaaaaaatt ttaatatatt taaaaattaa atttttaaaa acgaaagatg
     2461 agggaatggt atgcaggata aaagtgtgag ggagattaaa gaaataatag agactttaga
     2521 agtagaaaaa tatatggaat atatagagct gttaagagtt gatgaaagaa aatctgtaca
     2581 aggtctagct ataaaactgg caaaaaagct ggataatatt agaaaagaag aagaaagatt
     2641 ggaaactata aatatatttg agaacgaagg ctatgataaa ggttatttat atattggagg
     2701 aattgatgag gcgggaagag ggccacttgc tggacctgtt gtagcttctg ttgtagtatt
     2761 taaaaaagat accaaaatag aaggtgtaaa tgactctaag aaactgagtg aggcaaaaag
     2821 agatgaactt tttgaagtaa taaaagaaga agcactagat tatggaatag gtatagtaaa
     2881 caatgaagaa atagatgaat ttaatatatt aaatgctaca tatatggcaa tgaaaaaggc
     2941 tataaattgt ttaaaaaaag caccagatta tttattagtt gatgcagcaa caataccagg
     3001 tattgacata tctcaaaatc caattgtgaa aggagattca aaatctatat caatagcagc
     3061 agcaagtata cttgctaaag ttactaggga tagtataatg taccaatatg atagagtata
     3121 cccagaatat gggtttaaat ctcacaaagg atatggaact aaagaacact atgaagctat
     3181 tgaaaaatat ggcataactc ctatccacag aaaaagtttt ttgaaaaata tactgtaaat
     3241 ataatatgat ataatgtata taatataaat tactatagtt aatgggggat taaagatgga
     3301 atataatgaa ttattaaaaa gtgctagaga aaatttaaat ggaagttgta aagtttgtaa
     3361 ggtttgtaat ggggttgctt gtgcaggtga agtgcctggc atgggaggta aaggaagtgg
     3421 ttcttctttt atagaaaata gcaagagttt agaaaaagta aaagtaaata tgagagtaat
     3481 acatgatgta tcaaatcctg atacatctat agagatgttt ggaaagaaaa tgagtgcacc
     3541 tatatttgca gctccagtaa caggaactac tttaaatatg ggtggaaaaa ttaatgaaag
     3601 agattacata gaaccagtag ttgcaggatg tgctaatagt ggtatttatg caatggttgg
     3661 tgatacggca gtagatgctt ttttaatgga aaatttagat gtagtcaaaa agtataatgg
     3721 agctggaatt gtatttatta aaccttggga taatgaaaat attataaaaa agataagatt
     3781 agctgaagaa gctggtgcat ttgcagttgg agttgatata gatgcctgtg gtctagtaac
     3841 tttatcatta catggaaaac cagtacttcc taaaaatgtt aaacaaataa aggagttagt
     3901 aaagtctact aaactaccat ttatattgaa aggtataatg actgttgaag atgctttaat
     3961 ggcagtagaa gcaggtgtgg atgcaatagt tgtatcaaat catggaggaa gagtgcttga
     4021 ctgtacacca ggagcatgtg aagttttacc aaaaattgct gatgctgtta aaggtaaagt
     4081 tacaatactt gcagatggtg gagtgagaac tggtttagac gtactaaaaa tgataggttt
     4141 aggtgcagat gcagtattaa taggaagacc ttttgtgact gcttcttttg gtggtgcaac
     4201 tgatggtgta gaaacttatg taaataaact tcaatcagag ctaagtagtt ctatgatatt
     4261 aactggatgt caaactataa aagatattga tggaaaagtt atatacaaat aaaattttat
     4321 acaaaaaaga ggaaaaatca ttttaatgta gaataattgt acaaaggggg aatttatatg
     4381 agtagaaaag cttatgaaga agccttagta gaattagaaa aatttattga tgaaagaaaa
     4441 gaaataatta aaagtgcgga ggactgtatt gataagtaca tagttgacag aacgctacct
     4501 tttgattaca aagataaatg tgtggaatgg caacaagagt tacttgatat tgcagaggca
     4561 caagttttag aagcaaatga attaagtgta ttattacaag agaaaaaaga acttgaagaa
     4621 gattaaattt tattagctaa gagtaaatca gtaatatgat ttactcttag ttttttttat
     4681 ttgaataaaa tacatctatc taattgagat aactttatta atattagatt aggcagttta
     4741 aaataagcta aagtagcatg gatgattagt ataaaaaata aaaccagttt aaaaaactgg
     4801 tttaatttgt attctttgaa tttaatatat gttttttcat ttcctctaat accattgtat
     4861 aggatttaca ttgagcagca gctaattctg ataaagcaaa tttttgagct ttatttaaaa
     4921 actccttatc tgtgctacac aattgttttg aactgtcttg tatcataagc attttgatta
     4981 attttacaat ttcaaaaaca tctcctgaat gaaatttatc ttggtacagt ttaagtcttt
     5041 cttttctatc aaaaatccat acaccatctg ttttattaat agattggata aaattatcaa
     5101 catcatttcc atccataact ggacgtatgc caattctatc tgcatttaga actggaatcg
     5161 aaattttaag gttactatta aaaatgacac ttaattcata gtatttttgc atctcatgat
     5221 ttattttctt tgttacaata tcatttacag agcaggctcc ctcttttgga tacattacac
     5281 tttcaccaat tttatacata tgctagttat acctccaaat tgaattttag atattgcaac
     5341 ttaggtacaa tgctttaatt atctaatgat taatattata acataaataa cttgacaagt
     5401 caaaaatatt aatatataat atgaagttta gacttggtga tgtgtgaaac taaagagaaa
     5461 aatataagat aaaataattt aatatgttga aatattcttt tacaattata taaaaataga
     5521 tactaattat atttaataat tattagtttt tagcaaaatc tcttagttta agacttcctg
     5581 cagttacaaa tataattcca attaatatta gagctattat atttattaaa atactaccat
     5641 tgtttttaat agcatctata gtccaataaa atggtgtgaa ctttgaaaga ttagtcataa
     5701 aggataattt atccattgat ggtattagac tagagataga tatagctaga cctattaaag
     5761 aataaaatgt agatataaga cttatagaac tttcattttt aaatactcta gctacccaaa
     5821 atacaaatcc agtggaaaca aaactatttg ctagtacaat catcaataca ttcagactca
     5881 aattaaagtc ttctataatt gaaaaacata atagagcaaa agtgtataca attgattgaa
     5941 taaaaaatag tcctaaaaat atactgaaaa ttatttttat atctttatta tctgtagaga
     6001 taagtctttt tagcacattt gattttttta atgtaaataa atcagaagca agatgtgccg
     6061 cattaatata cataaaatag catatcaaga agactactaa aaatgaacct ttattcttat
     6121 ctggtttgtt atcaattata tttgtctttg tcaatttatc atctatattt ttatccactt
     6181 tcaattttaa cgatttagta ataaaagatt ctatttgtga ttctgcccaa agactaccac
     6241 caccattttc aattttaaag catttaacta caggtcgttg taatttatct atactatttg
     6301 aaaaattttt atctaaaacg aatacagcag aaaccttatt attttttaat agattcatag
     6361 ccttatcttg ttcatttaat ctaaatgaat tttcttttaa tttagaacta tttattaact
     6421 tatgttcata ctttcctgaa gagtcaaata caattgctac tggagaaaag tacattgatt
     6481 gatttcctga gttgttgata aaaaaattaa gtgaaaaaat tagtataata ggaagcataa
     6541 ccatattaat taaaagagta tgatttttta gatatctttt tatatttgca atagttaatc
     6601 taatcattat taaacctccc tccatttata tttttccttt acaatagcaa gtgcaattaa
     6661 tattgtagag ataattaaac atgtgaaaat taaatctcct attgaatcta tagttttaaa
     6721 tgtttcataa ttactaaaca attctcctat taaataggta ggagataaac ttgtaagctt
     6781 agtaaatgta tcacttatca tactgaagat acctccaaaa attgtctgta aaaagagtaa
     6841 tgcataaact attgctgtac cgtatttttt actaaaaaag ctggttacaa aggtagatat
     6901 tgaagtcata aaataagatg ataaagcaca aagtaggagc aatatggcaa aattaccttt
     6961 aaatgttatt ccaagtattc taaagaataa aacatataat aataagaata taaatgaata
     7021 aatccataaa cctacaaagt cataaattaa gaattgtact ctagttatag gcatagaata
     7081 aagtcttttt gaaagtccct ttgattcact tatataattt gacaaaatat tgttcattat
     7141 aaaaattatt acaagaaatc ctagtgaaac taaagcaaag tattcataag agttctgttt
     7201 aacattgtta tttattatag aagtatcaat agaattttta ttaaataatt tagaaaaatc
     7261 ttctgaactt attttctgag aattatttaa ataaaatttt tcatggtaag tatctaatat
     7321 atcttgaagc aatattgcaa tatcatcacg agttccaagt ttttctatgt ttagagtatt
     7381 tgatttttca tttaataaac tactctcata gcctttaggt atagtaagct ttaattctgc
     7441 cttagaatca tcttttttaa ctgttaatat ataagataaa tcatttttca aatactttgt
     7501 caaatcattt gataatcttg tgttatcttt gtcatatata acaatggggg tagattctgt
     7561 ttttataggg ttttgaaaca tgctttctgt aaccatccca agaaaccaag ataaaatcag
     7621 aggcaaagct aaaaaatata ttaaattaag tataaaggag ctttttaaac tctttagcat
     7681 agtttttaca ctcatgtata atttcataaa atcacctcca ttagtccctt aaattttttc
     7741 ctgttagatt taaaaatacg tcttctaggc taggttcttc ataagaaatt ttcattattt
     7801 ttgaattgtt tttgtcaata acagagagta tatctgtaag ttgtaatttt ttatctatat
     7861 ccaattctaa taatgaatta ttttctaaaa cagatataac acctttagta ttttttaaat
     7921 caaagataag ttgggcattt atatttttta tttccataat caattttgta tttgtagata
     7981 cgagtgattt taaataatca ttatctccaa aagcaatttc tttaccttca tccataataa
     8041 aaattttaga acaaaggtgt tcaacttctt ccatataatg ggaagtatat attacagtag
     8101 tttcatgttt tttagatata tcttttataa aattgaaaat atgatttctt gattgggggt
     8161 ctacacctac agttggttca tccaatatta atattttagg atgatttaag agtgctattc
     8221 caatatttaa tctcctttgc ataccaccag ataatttttt gacctttttc tttttgactt
     8281 cagtaagacc tgtaacttct aatgcttcaa tgattctttc tttaagtagt tttcccttta
     8341 aaccgtagaa agctccaaag tactctaagt tatcaaaagg agtaagagtt tctataattg
     8401 ctaattcttg tggaactaac cctattatag actttgcttt tatataatct tttgataaat
     8461 ctaaaccatt gatttgaata ctaccactat ttggtaacat aagatttgta attatattta
     8521 taagtgtaga tttacctgca ccatttgggc caataagtcc aaatatctca ccttttttaa
     8581 cagaaaagct gatgttatca agtactaatt tatcattaaa tctttttgtt atattattta
     8641 ctctgactat atccatagta atccctccaa aataattttg tataagttaa aaagctataa
     8701 tattataata aagaattgtg aattataatt ctattactat aagtcactaa aaaaagtgac
     8761 ttaagtcact ttatattttt agatttattc tattacaatt ttatttttga aagcaaagat
     8821 tgctagttga gttctgtcac gaagttctag tttagctaaa atattagtta tgttattctt
     8881 tattgtacct tcagataaga atagttcttg acttatttct ttattattaa gtccatttgc
     8941 aattagtcta attatagata tttctttttc tgttaaattg tacatgtcat aaagatgctc
     9001 ttgtttaacc gttttttcag aggtcatgat tttttcagct acacttttat caagcacaat
     9061 attgccaaaa aatgaagaac gaatcccttc atgcaatact tcatcagagc tatcttttaa
     9121 aaggtatcct gaagcaccaa acttcatagc atcttttata tattcatcat cattaaaagt
     9181 tgttaaaatt aataatgtta tagaattatt atattccttt ataagccttg tacctagaac
     9241 cccatcacat actttcattc gtatatccat aagaactatg tctacatcat tcattttaca
     9301 aaattctaaa gcttcatatc cattagaagc atctcctaca atttctaaat cattataaga
     9361 tgataatata attttaagac cttttctaat taatttttcg tcatctacta taagaacttt
     9421 aattttattc aaaaaaatca ccccctgaaa atttaggaaa agaagctcta attgtgaaac
     9481 cattattaga attatcaaat tcaactttac catttaattc atatattctc tcattgatac
     9541 tattaagtcc atttcctttt tttatattgc cacatcctat accattatca ctaatagtaa
     9601 ttataagatt tgaagtattg aatgtaataa aaattctgat ttcagttgcc tttccatgcc
     9661 tagatgagtt ggaaagggat tcctgtatga gtctatataa agctatagat tgatttctgg
     9721 ataagttcca agtatttttt gaaatagtta atttaacatt aatatttgta agcttaataa
     9781 agcttttaac taattctttg attttaaata aactttggta attttcatat tcaacaggtt
     9841 ttaactcaga tatagccctt cttacatctt gaaaactttc agttacaaat tctctaagtt
     9901 catgtactaa gtcataaatt agaggtttgt cttttaagag tttttctata gcatttaatt
     9961 gtattattgt tgtagaaaga gaatgtccta cactatcatg tatttctctt gatattcgat
    10021 ttctttcttt taaaattgct aattcttcta tagaacttgc ataagtttcc aaatcagcat
    10081 taactttttt taattcatct ttagaaattc taagcttatc ataaagattt tgactgtata
    10141 attttgataa attctcattt tctatatata tagaaagtac agttataatt agcaatatag
    10201 agcttgactc cagtgccaaa tatatatttt tatctaaact aataataaga gaagatatta
    10261 taacaaaaga gaacaatatg tacttatatt tttcctttat taaaaatgat atatctaata
    10321 ttaaaggaac aaagtaaatc gaattaaaag tttttgtata attacaaagt ataaaaatta
    10381 atataagttc taaaaagtaa gaaataagta taaatttatt ctcatttgat aaagaaaaaa
    10441 atctaacttg attatttatt ataattagaa ataatattat catagttatg accggataca
    10501 atgtattttc aacatttttc aaatagctta caactaatat aaataaagat aaatatcgta
    10561 taaaagcaac taatttttct ctgttcatta aaggcactcc tccaaaaaaa taaacttttc
    10621 ctatgaaaac tagaataata tcataaaaga ataaagtcaa tagaagtatt tattaatatt
    10681 gatggaaata aaatcaatcc aaaaacttga atagtaaaat tgtatactga ccataattta
    10741 aaagtgaaaa tttaatgtat tggagtgaat aatgaataat aaagaaaaag gtgattttgg
    10801 agaaaaagta gcagttaatt atttgctatc aaaaggagca aagatactag aaaaaaatta
    10861 cagattaaag ataggggaaa tagatataat agcaaaaatg gaagatgaaa ttatatttgt
    10921 ggaggtgaaa tcaaggtcta acataaagtt tggctaccct tgtgaatctg taagcttcaa
    10981 aaaaagaaaa aagataattg gagttgcaag ttattatatt ataaaaaata acttaaataa
    11041 cactcccata agatttgatg ttatagaggt atatttatta gaaaaaagaa taaatcacat
    11101 aatgaatgct ttttaaaaaa gataatgttt ttggaaagga ttaaatatgt taagtattat
    11161 taattcaagc aacttagtag gaatcgacag ctttttagtt aaggttgaag tagatgtaag
    11221 caatggaata cctagtttta atattgttgg tcttccaggc aaagaaatta aagaagcaag
    11281 agaaagagta aagtcagcaa ttcttaatag tggatataaa tttccaagca cgagaatagt
    11341 tgtaaattta tcaccagcag atataaaaaa agaaggagct tttttagatt tatctataag
    11401 tataggcctt ttaagagagt taataaaaaa agatgaaaat tacataagag aaagtatgtt
    11461 tataggagaa ttatcattag atgggaaaat aagaaaagta agaggtatat tgcccataat
    11521 tatgggtgca aaaactcaga acataaaacg tatttttata ccaattgaga acataaaaga
    11581 aagtctattt gtagatgaaa ttgatataat tcctattaaa agtttaaaag aatgtgtcga
    11641 ttttttaaac gaagagataa aagtcgataa agtaaggata atgtcttttt tggatgataa
    11701 gtcaagaaaa gagaacgaag aattagaaaa agataatagt tatatagatt gcaaatatac
    11761 taagattaat aatgaagaaa gtaaatatga tgaagacttt aaagatgtaa aaggaaatta
    11821 ttttgtaaag aggagtgcag aaattgctgc tgctggaaat cataatatgt ttatgattgg
    11881 acctccaggc tcaggaaaaa ctatgattgc aaaaagagta aggacaattt taccagatat
    11941 aagtgtagaa gaaatgatag aagtaagtaa ggtctatagt atattgggta tgataaatga
    12001 aactaaagga ataattgata aaagaccttt tagagcacct catcatacaa ctacaaagca
    12061 atctttaatt ggaggaggaa tggatgcaag acctggagaa attgctttag cacatagagg
    12121 tatcttattt ttagatgaga tagccgaatt tgatagaaaa atacttgaga ctttaagaca
    12181 acctatagaa gatggatatg taaatatatc cagagtaaag tacagtgcaa aatatccttg
    12241 tagagtactg ttagttgcag ctatgaatcc atgtccatgt ggttattata tgtcagagac
    12301 agagtgtaga tgtagaagta acgaaattga tagatacata aataaaatat caggtccatt
    12361 gttagatagg tttgatattt ttgtagaagt taattctata aaatattcag attttaattc
    12421 tttaaaacaa gaagaaagct ctcaaaaaat aaagagaaga gtagaaaatg ctagaaaaat
    12481 acagataaat agatttagga aggataatat aaaaaataat agtgaaatta aagcttacaa
    12541 tttatttaaa tattgtaaac tggaaaaaga agcttcaaaa acggctgaga tgatatttaa
    12601 taaatacaac ctaagcagta gaagttatac aaaactttta aaaatggcaa gaacaatagc
    12661 agatttagaa gaaagagatt tgataaattc acagtgtatt atagaagctt tttcatttag
    12721 aaaggcttat tatagttatt ttaaatagtt ttttgaggtg gattttatgg aaaaaagaga
    12781 tacttattta tggttaaaat caattggtgg aataacaaca aaaacaattg aaataataga
    12841 aaatgaaata gtaaatattg aagatatatt tgatttttct gaaaaagaaa tatataattt
    12901 aaaaaatata agcttgaata ttagaaaaaa tatagtaaaa tatagaggtc acgcttattt
    12961 agaaaatata aaagaactac tttacaaaaa agcgattaaa tatatttgta aatatgataa
    13021 agaatatcct gaaaatttaa agaatatata caacgctcca aagttattat tctacaaagg
    13081 tgacataggt ttagttaata ataattttaa tatagctata gtaggttcaa gaaaacctac
    13141 agcctatgga attaattgtg caaaaacaat aagttgtcaa ctatcccaat atggagttaa
    13201 tatagtaagt ggattagcta taggaataga tgcatactcg cacataggtt gtatgagtgg
    13261 aaaatctaaa actatagcag tacttggttc aggagtagac aatcctcttc caaaacaaaa
    13321 tttacattta tcaaataaaa tattagaaaa tgggggatta ttattatcag agtataatat
    13381 taactcgaca gtagccccgt accatttttc taatagaaat agaattatca gtggtttaag
    13441 tgatggagta gttgttgtag aagcagcaat aaaaagtggt gcactaatca cagtagattt
    13501 tgctcttgaa catggaaaaa atgtttttgc aatacctggt aatataaatt ctcaaatgag
    13561 tagaggttgt cataaaatta taaaagaagg tgcaaaatta attgaaaata tagatgatat
    13621 tttaaatgaa tataacatat ttaatattat tgataaaaaa ataaatcaaa aatatgataa
    13681 tataagtcta aatgccaagt ctaagcaaat aattgaagct ataaaaagag aaggaaactt
    13741 gcatatagat agtatttgtg attatactgg tatagaaata aagtatgtaa attcaataat
    13801 caatgaatta gtactaaatg agttagtagt agaaatgaat aataaaacgt acagtttaaa
    13861 tgtataaatt aagattaggt agtgggggtg tatggtttta tggccaaaac attagtcatc
    13921 gtagaatcgc ctgcaaaagc taaaactata gaaaaatttt tagggaaaag tcattacaca
    13981 gttaaagcat cagttggtca tgtcagagat ttacctaaaa gtaaattagg tgtagatata
    14041 gaaaataatt ttgaacctca atatataaat ataagaggaa aaggcgatgt aataaaagaa
    14101 ttaaaaaaag aagctaaaaa atctaaacaa gtatatctag caactgaccc tgatagagaa
    14161 ggtgaagcta tatcatggca tttagctcat atactaaatt tagatgaatc tgaggattgt
    14221 agaatagagt ttaatgagat aactaaggat gcaattaaaa aagcaattaa acatcctaga
    14281 aatattgata taaatttggt tgatgcacaa caggcaagaa gagtgctaga cagactttta
    14341 ggttatcaaa taagtcctat attatggcaa aaggttagaa aaggtcttag tgcaggtaga
    14401 gtgcaatctg ttacaacaaa gttaatttgt gacagagaaa aagaaataaa ggcatttatt
    14461 ccaaaagaat actggacaat agatgttgag gctaagacag taaaagacaa agatataact
    14521 ttgaaatttt atggtaaaaa tgatgaaaag attgaattag aaaatgaaga agctgtaaat
    14581 gaaatactaa aagaaatgga aggtaaagat ttaaaggttg agaagataga atctaaatca
    14641 agacgtaaat cagctccaaa accatttaca acaagtatgc ttcaacaaga aggagcaaat
    14701 aagttatttt ttactactaa aaaaacaatg atgatagcac aagaattata tgaaggtatc
    14761 gacatagaag gtgaaggtac tgttggtctt atatcatata taagaactga ctctaaaaga
    14821 atatctgatg aagcaaaaga aaaagctaag ggctatatcg taaacaattt aggagaaaac
    14881 tactataaaa acactggtga taaaaaagaa aaaaaggata ctaaaaaggt tcaagatgcc
    14941 catgaggcaa taagaccaac ctcagttgat agaactcctg agagtataaa agcctcattg
    15001 agcaaagacc agtacaagtt atacaattta atttggagaa gatttgtagc tagtcaaatg
    15061 gaagattcag tgtttgatat actaaatgta gaatgtaaaa taggcgatat tgtatttaag
    15121 gcaactggtt caaaaatgaa atttgatggt tataccaagg tatataattt ttcagaaaga
    15181 gaagacaaaa ttttaccaag tatagaaaaa ggagatatat taaatataga aaatatattg
    15241 ccagaccaac attttacaca accaccagca agatatacag aagctagttt agtaaaaaca
    15301 ctagaagaac taggtatagg tagaccaagt acgtatgctc caacaatagc tactatactg
    15361 aatagagagt atgttgaaaa gcaaggaaca agtctatgtc caacagaact tggaataata
    15421 gttactgata ttttggaaaa taatttccat aaatttatag atgtagattt tactgctgat
    15481 atggaaagta aacttgatgt tatagaagaa ggcaatacag attggaaaaa gattgtatca
    15541 gaatcatatg caccacttaa agaggctatt gaagaagctc ttgaaaatat agaaaaagta
    15601 aatatggatg aagaaactga tgagatttgc gagaactgtg ggtctaatat ggttatcaaa
    15661 tatggtagat ttggaaagtt tatggcttgt aaaaactatc ccgattgtaa aacaactaga
    15721 ccaattatga ataaaattgg tgttaaatgt ccaaaatgtg aagaaggaga tattatactt
    15781 agaaaatcta aaagaggtaa agctttttat gggtgttcta attatccaaa ctgtgacttt
    15841 gtagcttgga ataagccaac aggagagttt tgtgagaagt gtggttcata tatggttgaa
    15901 aaagtgacta aatctgaaac aaaaacagtg tgttctaata aagaatgtaa taaagagaca
    15961 aaagagcata atgacggaaa agagtgaaaa ttgaaaaaaa tcacataatt ctcttgaaaa
    16021 aggttccaat ctatgataat ctttcaagtg taaacaacta atagaaaaat aaattttcat
    16081 taaatgtgaa aataatatta gaaaatataa aaggttatta aaaggcctaa atttcatgag
    16141 gagatgatta aatggcaagt gaagtgttac aaaaaacaag gaaaataaat aaaacattac
    16201 aaacaagtgg tggaagcagt gtctcttttg atttactggc cggagcattg ggcgacgttt
    16261 taagttctaa tgtttatgta gtaagtgcaa aaggtaaagt actaggtctt catttaaatg
    16321 atgttcaaga cagttcagtt atagaagatg agtatactaa gcaaaagaaa ttttcagatg
    16381 aatatactca aaatgtgtta aaaattgatg aaacattaga aaatttaaat ggtgagaaga
    16441 tattagaaat ctttcctgaa gaacatggaa gattacaaaa atatactaca gtagttccaa
    16501 tattaggaag cggtcaaaga ttaggaacat tggtactttc aagatattca aattcattca
    16561 atgatgatga tttagtaata gctgaataca gtgcaactgt tgttggtctt gaaatattaa
    16621 gagcaatagg tgaagaatta gaagaagaaa tgagaaagaa agctgtagtt caaatggcaa
    16681 taggcactct gtcctactcc gagcttgaag cagttgaaca tatttttgct gaattggatg
    16741 gaaaagaagg tctacttgta gcaagtaaga tagctgatag agttggtata actaggtctg
    16801 taatagtaaa tgcacttaga aaatttgaga gtgcaggtgt gatagaatca agatcattag
    16861 gtatgaaagg tactcatata agaatactta atgacaaact tacagatgaa ttaaaaaaat
    16921 taaaaaacaa tcaataatct atattttata ggtttagatt agaaaaggta tctatttgaa
    16981 atagatacct tttttagacg aattattaag gtaatgataa gtatattaaa aaggagtgag
    17041 aaaatgcctt tagcagataa aataagacca aaaacaatga atgatgtaat aggtcaaagt
    17101 catataatag gtaatggaaa aatattgtct aagatattac aatctaattt tttaccaaat
    17161 atgatatttt ttggtcctcc tggtgttggt aaaactacag tagcggaaat aatagcagaa
    17221 agaagcaata aaagcttcta taaaataaat gctactaatt catctttaga agatataaaa
    17281 aaggtgatat cagagcttgg aagtataaat aatgtaaatg gagtcctatt atatatagat
    17341 gaaatacaaa gttttaataa aaaacagcaa caatcaatat tagaatttat ggaaaatggg
    17401 agtataactt tgattgctag cactacagaa aatccatatc attatgtata taaagctctt
    17461 ttaagtaggt ctactgtatt tgaatttaaa cctttagaaa aacttgatat agaaaaagga
    17521 ctgaaaagag ctgttgaagt attaaatgaa gatagctata tggatattga gtgtaataat
    17581 aatgctattg aagatatagc aattctttct gatggagata tgagaagagc cttaaatatt
    17641 ttagaagtgg tagtctattc aactaaacca aataaggata atataactta tatagattca
    17701 gatgtaataa gggcatctac atttaataaa attataaact atgacaaaaa tggtgatagt
    17761 cattatgata ttttaagtgc atttcaaaaa tctataagag gaagtgaccc acaggcatct
    17821 atacactatc tagcaagact tataaaaggt ggggatttga taagtatatg taggagactt
    17881 ttagtaatag ctagtgaaga tataggctta gcttatccaa atgctattgt aattgtaaag
    17941 gcatgtgtag actcagctat gcaacttgga tttccagaag cgaaaatacc attagcagaa
    18001 gctactattc ttttggctac atctccaaag tctaattctg catgtatagc aataatgaaa
    18061 gctatggatg aactggataa agagtttgtt aaggatatac caaatagtat aaaggatgct
    18121 cactattctg gttctaaaga aataggtagg ggttgtggat acaaatatcc tcataatttt
    18181 aaaaatcatt atgtaaagca acagtattta ccagatagca taaaagatag tatttattac
    18241 ataccacaag aaaataaaac tgagaaaaat ataaaaaaat atttagaata tctaaatggt
    18301 gatttttaga ctgaacttta tgtatcgggg gtagatatta tgattataaa acttaactca
    18361 acttatcaca gtagagttat gaaatactta aaaaaagaac ctgagtacaa tttgtttata
    18421 ataggggata ttgaaagata tggatatgga aataattttt taaatatatg ggcagatgtg
    18481 ggtgaacatg gtgaaataaa ggcaatatta cttaaatatt ttgaatttat gatgttttat
    18541 tctgatggag agtatgatgt tgaaggtttt tataatctac ttcgtaatac taattacgaa
    18601 gaaatatctg ggaaaatatg tgctgtagat gctttagcaa agagattagg acttaataat
    18661 ttaaaggtag ttgatttttg caaacttcaa actaaaaagt ttttgataga taataattgt
    18721 aatgtaaagg ttaagagaat tagacttgga aatctaaaaa agacagtaaa actttatgac
    18781 ttaatagatg aatttcacag tacaacttta gagaatttaa aaaatggact aaggacaggt
    18841 agaggatatt gtatagagat taacaaacag gtggtgtcaa tggcaaagag tacttcagaa
    18901 aataggactc atgcaatgat aattggagta ggaacacatc ctaaatatag agctaaagga
    18961 cttgctacaa aatgcctaat taaactatgt tcagagttac tgagagaaaa caaaattcct
    19021 tgtttgtttt atgataatga agaggctgga aagatatata aaaaactagg atttgaaaac
    19081 attggaaaat ggggaattta ttcaaaataa aaaattaaaa ttaatcttga caaaattagt
    19141 agggtataat aaaattatct tgaaagtaat tcctactaaa acagtatgaa ttagatttct
    19201 atatagaggt gataatatat gaagttgtct actaaaggta gatatggact aaaagcaatg
    19261 tttgaattag cattaaatca agacaatgga ccagtatcat taaaatttat tgctaagaag
    19321 caaaaaatat cagatcagta cttagaacaa atattttcat ctttaaaaaa atcgggtcta
    19381 gtaaaaagtg tgagaggtgc tcaaggaggt tatttgcttt caaagaatgc tgaagacata
    19441 acagtaggag atatacttgt agtattagaa ggaccagttg cattatctga ctgtgtacta
    19501 gatgaagatg tatgtgaaaa ctcaaacatg tgtgtaacaa aaatagtttg ggaaaagatg
    19561 aaaaagggta tagaagatgt tatagattca attactctta aagatatgat aaatgactat
    19621 aacaaaaata aattagaaaa tgatataaca aatattaaaa aatagatttg gagatgaatg
    19681 taatggaaaa aagaagattg tatatggatt attctgcaac aacacctatt aaaaaagaag
    19741 tattggatgc aatgatgcca tacctaacag attattttgg taatgcatct agttttcaca
    19801 cattcggaag agaagcaaaa gatgctttgg ataaagcaag agaacaagta gcagccctta
    19861 taaatgctga acctagtgaa atatatttta cagcaggtgg ttcagaaagt gataactgga
    19921 cactagaggg tgtagcttat gctaataaaa acaaaggtaa tcatataata acttcaaaaa
    19981 tagaacacca tgcaatactt catacatgtg aatacttagc aaaacatcat ggatttgaaa
    20041 taacttattt agatgttgat agcgaaggaa aagtagactt aaaacaacta gaagagtcaa
    20101 taaaagatac tactatactt ataagtataa tgtttgcaaa taatgaaata ggaactatac
    20161 agcctattaa agaaatatcc gaaatagcta aaaaacataa gatattattc cacactgatg
    20221 cagtacaagc tacaggtaat attccagtag atgttaaaga attaggaata gatttgatga
    20281 gtatgtcttc acataaaata tatggaccaa aaggtgtagg agctttatac ataagaaaag
    20341 gtgtaagact tcataacttt gtccatggtg gagcacaaga aaaaagcaaa agagctggta
    20401 cagaaaatat acctgcaata gttggatatg gaaaagcagc agaattagct aaggaaaata
    20461 tgcaaaatca tgtagaaact ttaactcgtc ttagaaataa gttaatagat ggtgtgttag
    20521 aaagaatacc ttacacaaga gtaaatggta gcttagaaaa tagattgcca ggaaatgcaa
    20581 actttgcatt ccaatttata gaaggtgaag gaatactttt attattagat atgttaggaa
    20641 ttgctggttc aagtggttct gcatgtactt ctggttcatt agacccttca catgtacttc
    20701 ttgcaatagg tttaccacat gaaatagcac atggttcatt aagacttaca gttggagatt
    20761 ttacaacaga tgatgatata gattatatac tagagaactt accaaaagta atagaaagac
    20821 ttagaagcat gtcaccactt tatgatgatg cgaagaaaca aggtttagta aaatagacat
    20881 aaagataaag cataaaaaat agacataaat tgagtaggag gaaaagataa tgcaatatag
    20941 tgataaagtt atggaacatt ttatgaatcc aagaaatatg ggagaaattg ataatgcaag
    21001 tggtgtaggt gaagttggaa accctacatg tggagatata atgaagatat ttttagacat
    21061 agatggagat gtaataaagg atgttaagtt taaaacattt ggctgtggtt cagctatagc
    21121 aagttcttct atggcaactg aaatgataaa aggaaaaact ataaaagatg cattagaact
    21181 tacaaataaa gctgttgcag aagctttgga tggtttacca ccagtaaaga tgcattgttc
    21241 agttttagct gaacaagctg taaaagcagc tcttatagat tatgctcaaa agaacaatat
    21301 ccatatacca gaattggatg gatatgttat agatgatgct catgaccatg atgttgaaga
    21361 agaagaataa aaataagtga ttgtgttatg agaagtttac aatgattaaa aagaagtact
    21421 aatgatataa ttaggacata aaaaatagct gtttttaaaa tggctatttt ttattgccta
    21481 aattaagtat tttaacttga tttagaggtt aattagttaa caaaataatc cataagattc
    21541 aaataataaa gatgattatt tttttagaaa atagaacaag ctatatttta aataagtaca
    21601 atacttgcta tatatggtat aataataagt aatgcaaaag atgaggtgaa atttgtttat
    21661 gaataaaaaa gtaatgatag gtatgagtgg aggagttgat agctctgtag ctgcatatct
    21721 tttaaaacaa caaggatatg atgtcattgg tgttactatg aagttgtggc aagatgatga
    21781 tgttgttgaa attgaaggtg gttgttgttc tttatctgct gttgaagatg ctagaagggt
    21841 agcaaataaa ataggtatac cattttatgt tttaaatttt agagaagtgt ttaaagaaaa
    21901 agtaatagat tattttatag atgaatattt ggaaggaaaa actcctaatc cctgtatagc
    21961 ttgtaataaa catataaaat ttgatgattt ttataagaag gctagacaaa taggttgtga
    22021 ttatgtagct acaggtcact atgcaaagat agaaaaggat gaaagtacag gaagatattt
    22081 gctaaaaaaa tctgttacag ataaaaaaga ccaaacttat gcactttata atcttacaca
    22141 agagcaacta gagcatactt tattgccaat aggtgactat gaaaaagata gagtaagaga
    22201 aattgctaag gaaatgggta tggcagtaca caataagcct gatagtcaag aaatttgttt
    22261 tgttaaagat aatgactatg caaattatgt aaaaaaacat tctaaaaagc gtattgaaga
    22321 aggttttttt gtagatacta aaggcaatat acttggaaaa cataagggta tattatatta
    22381 tactataggc caaagaaaag ggcttggaat tacttttgga aaaccaatgt ttgtaataga
    22441 cataaatcca ataaataata ccatagttct tggagacaat gaagatttat ttaaaaagga
    22501 acttattgct aaaaatgtta actttatatc aatagatacg ttagaagaac cattaagagt
    22561 tcaagccaaa ataagatatt cagcaaaacc atcaccagct actattcata gagtaggaga
    22621 agatactatt aaaatagttt ttgatgaagc tcaaagagct attactaaag gtcaatctgt
    22681 agtaatgtat gatggagata ttgtagtagg tggaggtata atcgagaaaa gtttataaaa
    22741 acatctaaaa aattaaaaaa ataaacaata aagtatatta agagtaaata aagtttataa
    22801 aataaattta ttgtatatga aaatatagta ttgattaatt ttgtaaaatt tagtaatata
    22861 attagtatat taattaaaaa acaaatacag tgataaggaa tagtaaaata tttgatgtct
    22921 tacagagaga gggaaatgct ggaagccctt agaatatgat atttgaagca gccttttagt
    22981 agcaatcttg aacaatttat attttataaa gaagatttaa gtagagattg acggtagtta
    23041 cgttatagct aaggttttcc gaagatatca tactttgtat gataattagg gtggtaccgc
    23101 gattgtcctc gcccctataa atttatttat agggacgagg ttttttattt aaacgaaaaa
    23161 ataaaattta ttaggaggaa catgatatgg aaaagatggg attaaatgaa ataagaagta
    23221 agtttttaga attttttgag tcaaaaggtc attatgtagc aaatagttat tctttagtac
    23281 caaacaatga taagagtttg ttacttataa actcaggtat ggcacctttg aaaaactact
    23341 tttcaggtgt agaagtacct ccaagtgtga gaatgtgtac atctcaaaaa tgtataagaa
    23401 caggagatat agaaaatgta ggtataactg caagacatgc tacattcttt gaaatgatgg
    23461 gtaacttctc atttggagat tactttaaaa gagagtcaat caaatgggga tgggaatttg
    23521 ttacagaatg gctaaatata ccagaagata agatatgggt gactgtatat gaagaagatg
    23581 atgattctta tgatatatgg gcaaaagaaa tgaatttccc agaagaaaga atggttagac
    23641 ttggaaaaga tgataatttc tgggaaatag gtacaggtcc ttgtggtcct tgttcagaaa
    23701 tatattttga tagaggagaa gaatatggat gtgacaatcc agactgtaaa ccaggctgtg
    23761 attgtgatag gtatttagaa ttttggaacc atgtatttac tcaatttgat agagatgaag
    23821 aaggaaatta tagtctatta gaaaacaaga atatagatac aggtatgggt cttgaaagaa
    23881 tgggttgtat tatgcaaggc gtagacacta tctttgaagt tgatacaatt aaatctatac
    23941 tagaagcagt tgagaagtta acaggagtaa aatatggaga gaatccaaaa aatgatatat
    24001 caataagaat aataactgac catataagag ctgtaacatt cttagttagt gatggagtgc
    24061 ttccatcaaa tgaaggaaga ggatatgttc ttagaagact tcttagacgt gctgctcgtc
    24121 atggtaagtt attaggagta aaagaattat ttttacagaa actaatagat gaagttataa
    24181 aagtaaatga taaagcatat ccagttttag ttgaaaaaga aagttatatt aaaaaagtag
    24241 ttggaataga agaagaaaaa ttcaatgaaa ctatagacca aggaacagaa atattgaact
    24301 cttatataga agtattaaaa aatgaaggaa agactgtcct aagtggtcaa gaagctttta
    24361 aactatatga tacttatggc ttccctatag acttaactaa agaaatatta gaagaagaac
    24421 atctatctgt agatgaagaa gcttttaatg aagaaatgga aaagcaaaaa gaaagagcta
    24481 gaaatgctag aggaaatatg gatggagaaa gttggaagga agaccctcta tcaaaattag
    24541 aatctacagt tgacagtaca tttaatgggt atagtgaaat ttatggtgaa ggaactattg
    24601 aagctatagt taaagatgat gagctagttc aaagtgcaga agaaggcgat aaggtatcta
    24661 tagtactaga taacactact ttctatcctg aaggtggagg acaagttgga gattgtggat
    24721 tgataactaa tgaaaactta gttttagaag tattaaatac taaaaaaggt gctaataata
    24781 gtataaaaca tataggtata ataaaatcag gaagaataag taatggggac aaagtaaaga
    24841 cactcgtaga tagagaaact agaatgtcag ctgcaagaaa tcacagtgct acacatttac
    24901 ttcataaggc attaagagaa gtattaggag aacatgttaa tcaagctggt tctttagtaa
    24961 ctccagaaag acttagattt gatattactc actttgaagc aatatcaaat gaagaattaa
    25021 aagtaataga agaaaaagta aataatgtta ttttatcatc tttagacata aaatgtgata
    25081 ttatgaatat aaaggaagct aaagaaaaag gagctacagc actatttggt gaaaaatatg
    25141 gtgatgaggt aagagtagtt tctatgggag attattctac agaactttgt ggaggaactc
    25201 acttgacaaa tacttctcaa gtaggaatgt tcaaaatatt atctgaaggt ggagtagcag
    25261 caggtgtaag aagaatagaa gcaataacag gaaaagctgt ttatgaatac ctaaaagaaa
    25321 gagatggaat tatctctgaa gtttgtgtaa acttaaaatc taaagaagat aatttaattc
    25381 aaagaataag ttctttatta gaagaaaata aaaacttatc taaagaattg catgatatga
    25441 aagctaagat gagtttacaa tcagttgatt ctatttttga ttctaaagtt gaagtaaatg
    25501 gagttaattt gataactaat aaatttgaag gtatggatat ggatacacta agagaaacag
    25561 cagataatct aagagataag cttggttctg gtgtagtagt acttgcaaat gtagtagatg
    25621 ataaagttaa ctttgtagtt actgccacta aagatgtatt agataaggga atacattcag
    25681 gtaatattgt tagagaagtt gcaaaaatag ctggaggaaa aggtggagga agacctaata
    25741 tggcacaagc aggagctagt gatgtatcta aggttgacca agctttaagc tatgcaagtg
    25801 aggttattaa gacacaagtt aaataacatt cactcaagga ggtttttagt ttggaaaaag
    25861 atttagacta cactatgaaa tttgaaggaa taccagaaga taggatgagt gtaggagata
    25921 ctattgattt tgtatataaa gcattagttg aaaaaggata taaccctata aatcaaatta
    25981 tagggtatct cctttctggt gattctagct atataactag tcataaaaat gcaagagcta
    26041 taattaaaaa atttgaaaga gatgagatac ttgaagaagt aatcacgcac tatctgaata
    26101 gaaagtaggt caaataaatg agaaaaaaga ttatgtcgtt gtttgcaata gtcattatga
    26161 tttttgtatc aactgctagc tatggttttg ctgaagaaaa aggcaaggtc atatttattg
    26221 atatgaatag gaccaatctt ggaagtatga tgaatattcc aatcttgaaa aatgagatag
    26281 aaaagagagg ctatgtagct ctcatgaata taagagggga tcaaggtact gatgatagaa
    26341 ggtcttatgc aagtatgggt gcaggaacaa gagctagtgt aactactgaa gactatatca
    26401 attttcaaaa agtagaccaa gatactgcta aagcttttga agtcgcaaca ggtcaaaaag
    26461 ctaaagaaat aaatgattta ggcattaata gatctataaa tgaaaatctt gagtatggag
    26521 aatatggagc aaatttaggg tcattaggaa aaactttatc agaaaatggt ttaaagacat
    26581 ctgtaattgg aaatgctgat ataattgaaa ataatcaatt agttaaaaac agaaacttat
    26641 gtttagtagc tatggaccaa tatggaagga ttgattcagg taatattgat aatattaata
    26701 agaaagattc taaaatgcca tttggaatat ctacagatta tgataaatta ctagatgaaa
    26761 ctaaaaaatc ctataaaaat agtgatgcta tatttgtaga acttggagat acatatagat
    26821 tagatatgta tagattaaat ctaaatgata atacttatga tacaatgaag aaaaatattg
    26881 taaaaaatat aaataaatat cttgaacaag tattttctat ggttggagaa aatgacactg
    26941 tttatatagc aagtgcattt ccaagtgacc tagattataa gaataagaga agactttctc
    27001 caataataaa atttagtgga gaagggaaag gtctactgga atctgccaca acaagaaaag
    27061 ctggaattgt tgccaattta gatgttggag tagatatact aggtacattt ggtcttgaaa
    27121 ataaagagat ggtaggtaga agttatactt tagtaaataa agaggacaat attagctatc
    27181 taaaatcact ttatgaaagg atagtgtcta tatcttcaat aaggtcaact attataaatg
    27241 gctttgtagg cgtaatatct gcttcttggg taattgccat gtttgcgatt ttctttagaa
    27301 attatatgcc acataaagag cgtgtattca aagtacttaa ggagtttata aaattaggca
    27361 taataatgcc actatcattt atgttagctc ctttgatgaa ttttaaaact ccaatttcaa
    27421 tatctttggg aatatttgca actacgctaa tattatactt gttaggtaga aaattattta
    27481 aggacaatga tataaagcac atgggatttt ttgcaacact tactatttta gtcatagtta
    27541 tagattctgt atttggaaca tacttaatgc aaaataacat aatgagttat gatgctgtca
    27601 taggagctag gtactatggt gtaggaaatg aatatgaagg tgtaactata gcaagtgcag
    27661 tatttggctt agcagtatta ttacattata agaaggtatc taaattactt gttgtaattt
    27721 tttcattaat aatacttata actagtgcat atccttcaat gggtgcaaat gttggtggag
    27781 ctatatcaga atgtgtagca tatttgttgt ttataatgct tatatatgac attaaaatag
    27841 attttaagaa agctgtatta ttagctgttt cagctgtagt tgtcgttttt gcatttgcag
    27901 ctttagatat actttcaggt agtgaatctc atttaggtat gtttgtacag agaattttcc
    27961 taaatggacc aggagagata ttacaaacat ttggaagaaa aattcaaatg aatatgcaac
    28021 tagcacagac aagtgtatgg gtaaatattt tacttgtagg aattggagta attgcagtgc
    28081 ttatatttaa accatctaga cactttagaa agataatgaa taattttcca atcttgttta
    28141 aagggtttat tgcatctatg gttggttgta taattactct tttagttaat gattctggaa
    28201 tagttgctgc atctacagca tctatatata tacttatacc actaataata ataagtataa
    28261 atatgataat atttgaaaaa aataactaaa aaaattttta ctgttcatat aggatttaaa
    28321 taaaaaatgc aatatgatta ttaatgtaaa ctggatgctt acataaaaaa tcatattgca
    28381 atttttatga ttgattatgt aaaattatat gaagcagtaa gcctgtgacc ttagttatga
    28441 gaggttcaga atatgtattt aatctataga atataaatag ataaaggagg aactatgtta
    28501 gatggaagaa taatgggtct tgatgttggt gataaaacta ttggagttgc tgtgagtgat
    28561 ttgatgggat taactgcaca aggtgtaaaa acaataaaaa gagttggcaa gaaaaaagat
    28621 attgaagagc taaaagcaat aataaaagaa aaacaagtaa ataaaattgt atcaggatta
    28681 ccaaaaaata tgaatggaac tttaggtcca caaggagaaa aagtaatcaa gttttgtgaa
    28741 ttggtaaaag cagaaacagg tattgatgta gagttttggg atgagaggct ttctacagta
    28801 gcggcagaga ggtctttatt agaagcagat gttagtagac aaaaaagaaa aaaggttata
    28861 gatatgttgg cagcagtaat aattttgcaa ggatatttag attttaaaat aaattcataa
    28921 aagaactata aaattgaata cttatgatat ataatataaa taataaaaat aaaaataaat
    28981 ttgaggtgaa tgacattatg gaagaaaata taataaattt aatagacgaa aatggcgttg
    29041 aaagccaatt tgaaataata ttaacattag aagcagaagg aaaagagtat gcaatattaa
    29101 tgcctttaga tgatgaagaa gcagaagaag ctttaatctt tagaattgat gaggatgaag
    29161 aaggtgaaat cttaatacct ttggaaagtg atgaagagta tgaaactgtt gtagctgtgt
    29221 atactgctat aatggaagaa gaaggtttaa attacgacga agatgaatca aatggactta
    29281 actagataag taattaagtt tgtatataaa aatcagatat ttattatatt tgctttaatt
    29341 aaaccttatt aattgtaaaa gcatttatag tatatatctg tttttttgtt ttttattaaa
    29401 aataccaaaa aatttatgaa ttttggtgaa taatatatct tttatgggta tatatttata
    29461 ttatgagaat aaattaaatt tatttaaatg tcttgacaaa aaatgaatta tcaattacaa
    29521 tattatttaa taaagattat caattgaaaa tagtaagggt gatgttatgg caaatacaat
    29581 ggatttatta aaagacaagt taaaagaaac tggttttaag attacgccac aaagaagagc
    29641 aatagttgaa atattgctta aacatgacca ttcacatcta agtagtgagg aaatctatga
    29701 tttagttaga gttgactgtc ctgaaatagg cttagctact gtatatagaa caatgcagct
    29761 attggatgaa ataggattaa tatcaaaact aaacttagac gatggatgta taagatatga
    29821 gattagtcta cataaagaag actgtcataa tcatcatcat cttatttgta aaaattgtgg
    29881 aaagataatg gaagctaaag aagacctttt agacaatata gaaaaagaga tacaatcatt
    29941 gtacaaattt aaaatacttg atcatgatgt taaattttat ggactatgtg acgagtgtaa
    30001 tggagtaagc gattcagaag aataaacttc tattgcttaa tgtcgatgga agaatagtat
    30061 agaactttta tattctatgc tattcttcca ttttttatta taaaccatct ataaaatgca
    30121 aatatacagt tttcaagatg cttatagttt taatattgaa aatataatta atcctataag
    30181 tacaaaaatg aatgattttt ctatgaaatt actaaatggt cctccaacag ttaaaaaacc
    30241 taaagaaatt ttcttttcgc ttagcggata aaaaattggt attccttgct ttgtaaataa
    30301 atctcctaaa aacatatgac ttgcataacc aatcgtacca taaaaagata aattattaat
    30361 attagtgatt aattctatct gttttagtaa aaaatatact attatagttg caaatatgct
    30421 atgagaaaaa cttctgtgct ttaaccaggg aaaaattgac aacattagac aaaaaattgt
    30481 aaaatatatt tcaacttcta tgatgtataa gcatatagct aatagtataa atattaatga
    30541 tagaaaaact tttcttagaa atgtgtgggt tagttttgct tcaataatta taattgcaac
    30601 aaatgtaatt attgcgctta aataaaaatt atcatttata tttattgaaa taaagaaaat
    30661 aataatatta acagcatata taaaaattct atatatgtat ttggatacat tgttttttag
    30721 aatgaaattt gagaccatag aattagattt atccaaatcg ggtagtacag caaaagtagc
    30781 tgaaactaaa atatcaacta aagatatagg aattttaaat attaaagatg tttggatagc
    30841 tgttaagatt cctattgcac aatgagtttt accacgcata aatcctccta aattatccga
    30901 tattaaatca tataatattt agaggatatc aaaataaaat aggtttgtca aaataatacg
    30961 ttaaatgtat tttaaatata gcttaaaata tgatacgaat tatggtacaa taagaataac
    31021 tggtagcgag tgcgtgattt gatattattt atgattgtag aacgtgttaa aaaattaaat
    31081 agacagaagg agatgatgca attgttcaaa aagaacacca acaagataaa ggtaatggcc
    31141 ttgggtggac ttaacgaagt tggaaaaaat atgactgttg ttgagtataa agatgaaata
    31201 attgttatag atgcgggact tagttttcca gaggatgaaa tgttaggagt agatatagtt
    31261 ataccagata taacttattt agtaaaaaat agggataaaa taaagggtat atttattaca
    31321 catggacatg aagaccatat aggagctctt ccatatatat taaagaaaat aaatgtacct
    31381 gtatatgggg caagacttag tataggtctt atacaagtaa aacttaaaga acataaaatg
    31441 aataatgtta agttaaatgt tataggtcct agacaagtta taaagcttga taatatggaa
    31501 gtagagtttt tgaaaaataa ccatagtata ccagatgctt actctattgc aatacacaca
    31561 gaccaaggta taatatacca cacaggagat tttaagattg acttgactcc tattgatgga
    31621 gatgttatgg atatgcatag aatctgtgag ttgagcaaaa aaggagttct tttaatgctg
    31681 gcagatagta ctaatgcaga aaaaccagga tttactatgt ctgaaaagac tgttggggta
    31741 ggtcttgacg aattatttgc aaaaggaaat ggcagaagaa ttatagttgc tacctttgca
    31801 tccaacatac acagattaca acaaataata aatactgctg aaaagtttaa tagaaaagtt
    31861 gctatatcag gtcgctcaat ggtcaatgta gttggagttg caaaagaatt aggataccta
    31921 gatatttctg atgacatgct tatagattta aatgatatat gtaagtatga agatagtgaa
    31981 ttagtgataa taacaactgg ttcacaaggt gaacctatgt cagctcttgc tagaatggct
    32041 ttttcagagc acaaaaaagt agaaataaag agtggcgatt tagttataat atctgctcat
    32101 ccaataccag gaaatgaaaa attaatatca agagtaatca atttcttatt tgaaaaagga
    32161 gcagaagtag tatacagtga tatagctgat atacacgttt ctggacatgc ctgtcaagaa
    32221 gaattaaaac ttatacatgc attagttaga ccaaagtttt ttatgccagc tcatggtgaa
    32281 tatagaatgt taaaaagaca tgctgaaata gctgaacagc ttggtatgga caaagaaaat
    32341 atttttgtca tgcaaacagg agatgtttta gaattagata aaaattctgc taaggtagca
    32401 aaccgtatac aaacaggaaa catattagtt gatggtctag gagtaggcga tgtaggtaat
    32461 atagttttaa gggatagaaa gcatttatca gaagatggtc ttatgatagt tgtagttact
    32521 atttccaagg atgagggtaa ggtcttagca ggtccagata taatttccag aggattcgta
    32581 tatgtaagag agtcagaaga tttaatggat ggagcaaagg atataattaa gaatgttcta
    32641 aatgaatgtg aagagaaaaa tattaaagaa tgggcttatt taaagaataa tattaaagaa
    32701 aacctaaaag aatatttata tcaaaaaact aaacgaaatc caatgatact tcctatcata
    32761 atggaagtat aatataaaaa aactataaat ttgaaaatta gacctcttgt aatttttaaa
    32821 gtaatatcaa aaatccaatt gatattatct taagaattac aagaggtctt tttaatactc
    32881 attttaaaaa aaaatatatt acataaaata ccaattataa caatctttta ttagtaaaaa
    32941 ctaattatat ataaatttta ctgataggag gattcttatg gatgatgttt caagacaaaa
    33001 tgctataaaa gctttaaaac aaacaaaaat ggaaatagca ggagagtatg gaatgaatta
    33061 tgaagatgct tttgaaataa tagaaaatgc gtctaataaa ggtgttttag aaggttactt
    33121 taaaaagctt gaaaagaaaa aaaatttagg tcaaggtata tctaggcatt tagaataaaa
    33181 aaagttaaat gtgagaaaat aagtttaaat aaactttaag aggtgacatc gatgaaaaaa
    33241 ttagctagta ctgctttggc tatattaatt gcgcttactc ctttaagctt ttcttttgca
    33301 aataataagg aaaatgctga tgccaaccaa ctaaatatat cttcaaaatc agcaattttg
    33361 atggatgttg gtagtggaca aattttatat gaaaaggatg ctcataaaaa gcttcctcct
    33421 gctagtgtaa ctaaggtaat gactatgcta cttatagtag aagctttgga ttcaggcaag
    33481 attaagcttg atgatgaagt tcaagtaagt gaaactgcat ctagtatggg tggtagtcaa
    33541 atattcctag agccaggaga aactcaaaag gttgatacat tattaaaagg tatagctgtt
    33601 gcttctgcaa atgatgcttg tgttgctatg gctgaacact tagctggaag tgttgaagga
    33661 tttgttgata gaatgaatgc taaagcaaaa gagttaaata tgaatgatac tcattttgca
    33721 aatacaaatg gacttccagt tgcaaaccac tatacatctg ctcatgatat agctttaatg
    33781 tctagagaac tattaaaaca cgaaatgata agtaaatact taactacatg gatggataag
    33841 gttgtagtag ggaagaaaca agttacagta ggtcttgcaa atactaataa acttataaag
    33901 cattatcaag gagcaactgg tgttaaaact ggttttactc aagaagcaaa atactgttta
    33961 tcagcatctg caaagagagg taatactcat ctagttgctg caactttagg agcagagact
    34021 tctccagaaa gatttaatga tgcctctagc cttttaaact atggatttgc taattatgaa
    34081 agtgttaagt tatgtagtaa aggtgataat atagcaacac ttacattgga taaggctgat
    34141 gaaaacaaag ttaaattggt tgctaaagaa gatttaaata ctcttattaa aaaaggaagt
    34201 tctaaagaat ttgagaagaa aattgaaata gtaaaaaatc ctaagatgcc aattaaaaag
    34261 ggaactgttt taggaaaaat aaagatatgt aaagataaaa aagtaatagg cgaagtggaa
    34321 ttgataaata ctaaggatat aaataaggca agctatctac aaatgcttca aagaataatt
    34381 gataatatga tataaataat tatcagatga aatataatta taatacacaa agatatgatt
    34441 ataatacaca taaaaaatac ccttatgtaa ttatttgcca taggggtatt tttatttacc
    34501 atatagaagt attttataat cttatgattt ttatagaaat atagaaaagt ttatgtatct
    34561 taaaatatca tttgatttaa tatcatatat agggttgttt aacaattatc taagtaaagg
    34621 catactacca gtaagtttat tcactttctt tttattccca taaattgcta tcccaaaata
    34681 ctgtaactca tcttctggaa cactagcaat cttttgtgta aattcttcat aaagattgca
    34741 actttgtgct acatctgaaa aatctacaac agttaaatcg ttaaattcca aagtatataa
    34801 ttttttacgt aaatctttta ttatttcttt gtttcctttt aaaataggta caggaatgtc
    34861 aataattcct aagtggctat tacctgtttt gtcaattaca tctgggccaa cagtttctgg
    34921 ggcatgtttt cctagtgtaa ttcccattat agctgctgta ttggatataa ttcccattgg
    34981 taaattttcg tctattacca tgacacattt tgaattttta ttttccattt ttatttctcc
    35041 tttttacctt atttaaagtt gtttgaatca tcatttataa atatattttg atactgcttt
    35101 ggtgtaagac caataaaatt cttaaaaaag tttgtaaagt gactttggtc tacaaatcct
    35161 gtttgtatcg cagcatctat aggttctacg cctttttcta aaagcttttt agctttgttt
    35221 acccgtatat tttctaggta tctatatggt gtaatacctt ttaatttcgt aaaattacga
    35281 agtagagagt acttattcat acctgctata gtgcttaatt cgtcaagtac tatatgttca
    35341 gcataattat tttctagata atcacatact gcttgaattt ctatatttgt attttccaag
    35401 ttagattgca aatttggctc tgtatgttct tcaattaatt gttcaattag gaagaaaaaa
    35461 agctcttcct ttttaaaatc caattcttct tccatgatta tatagtgtaa ttcttgtagt
    35521 agaggtacta gctcactgcg aaatataaca ggttgattaa attttggtaa ataattttta
    35581 cctgtaattt caaagacggt ttttttcatt atttctggct taatattaat acatctgtaa
    35641 tcaagtactt tatcatctat ttgttcacaa gtatgactat caaaagggtt aaaaagtagc
    35701 aaatctccag tacttgtggt atactcttta tttttacaag ataaatatct ttgacctttt
    35761 tctataaaac caattacata atgttcatga aaatggtttg ggaatttttg cattatgcct
    35821 ttaaatctat atgcttcaat ttttaattcc ctatcaaagc atactgtgcg ttcttcttgt
    35881 ctcacttagg taacctcctt tcatgttata caaagtgtaa cacatatttt tttatacttc
    35941 ttgtataata ttgactaaga gacaataatg tcaattcatg tcaatataat attatactta
    36001 cagtaggtgt aattattata ttttcacaat gaatatgata taataataaa agttataaaa
    36061 taaaaagcaa attttaattt tatgcctaga agttaaaatt attataatgt aaaataattt
    36121 tgattataag ctatttaatt gttataataa tattaaaaat ttaatttagg agatgtacat
    36181 taatgttaag tatgaatata ggagaaatag tagcaagttt agttggtata gctatggcaa
    36241 tatcaataca tgagtttggc catgcttatt cagctcactt gttgggagat gatacagcta
    36301 aagcttatgg tagaatgaca ttaaatcctg taagacatgt tgacccaata ggtcttttgg
    36361 ctatgtttat ccttaagata gggtgggcaa agccagtacc agtaaatcca aataacttta
    36421 aaaactataa gataggaaac ctgatagttt cacttgcagg cgttttttgt aatgttttga
    36481 ctgctatact gtgtgtaatt atcaataagt atgtgcatat gtacgctata aatacaatag
    36541 ctggatatgt gcttttatat agtatgggat ttgcagcttt taacttactt ccgatacctc
    36601 cacttgatgg atggggagtt atatctacat ttgtaccata taaatggaat gaatatttgt
    36661 ataaatttga aagtatgagt tatataattt tattaattgc tttatttact ggtatatatc
    36721 aaataatact atcaccaata tatacagtgt tgctaaaaat agtatattta tttgtttaat
    36781 ataataaaca gattaaagag ggattgatat gaagtataat atacaattac aagtctatga
    36841 gggaccatta gatttacttt atgatttaat aacaaagcat aaaatagata taaaggatat
    36901 atctataata gatataacta agcagtatct aaattatttg aaaatgctag ataaaatgga
    36961 tttagagata actagtgaat ttataactat ggcatcaaaa cttttagaga taaagtctaa
    37021 atatctgctt tataagcaaa aagatgaaga agaagaccca agaatagaac ttatggaaaa
    37081 gttagaagaa tatagaaaat ttaaggtagc atcacaagat ataaaagaaa atataactta
    37141 tgttaatgag agattttata gaaataaaga agagataatt attgatgaca atgtggattt
    37201 agaagatata tcaattgaag caataaaaaa tatacttcca tacatattta aagttaaaac
    37261 atcacagata gaaaatgcta atgatgagaa actagataaa atagtaagga agaaaataat
    37321 atctgtagaa gaaaaaatat tatatataag agatattata aaagataaga ttgaagttac
    37381 ttttacaaat attataaaat catatgaaaa tgatgaaata atagctactt ttttatctat
    37441 attagagctt ataaaagaaa aagaaatagt cgtagtacaa gatatatttt ttgatgatat
    37501 tctaataaga aaaagttcgg agtgttaaaa tgaaaagaga agatataaag tatattatag
    37561 aatctgttat gtttgcatat ggtgaaccaa taagtataaa agaattaaac tatataataa
    37621 ataaagaact ttcatcaaaa gaaatagaga ttatgttaaa tttacttatt gaggagtaca
    37681 gagaacaaaa tagaggtatt caaataatca agttagagaa taagtaccaa atgtgtacaa
    37741 ataaagacta tgcagaatat ataaagaaga ttattgaacc aaagaaaaag aaaagtttga
    37801 gccaagctac attagaaact cttactataa ttgcctacaa acaaccaata acaaaggtag
    37861 aaatagagga tataagagga gtaaaatgtg ataaggtatt acaaactttg tttgaaaata
    37921 aacttataag agaagctggt agattgaata agatagggaa accaataatt tataaaacaa
    37981 cagatgaatt tttaaagttg ttgaatatag aaagtcttga agaattgcca cctatagaaa
    38041 attatcaaga agtggcaaca aatgaataaa aatataaaat cacaataatt tagtatgtaa
    38101 ttttaaattt taaaagattt aaaatgctct aagttgttgt gtttttttgt ataaatataa
    38161 aattataatt ctcttaaaat aaatatggat aattaagtat aaatagtaat tttttgatga
    38221 taatataaac atggagctta atgaattatt taattttaag tatttaataa tagctgtaat
    38281 ttttattata agtgtaacta tgttgatttt aatatctcat ataaacatct taataatagc
    38341 tgatataaaa aacaaagata tttgtttaaa gcttaatata aaatacatgt ttaatttaat
    38401 aaatataaat agacaacttt atccagctga aaatagtaaa aataatgata aaaaagaggg
    38461 gatgaagaat aatatagatt caagtatatt attagctgat gaccttttga gcatttatag
    38521 attattaaaa aagataaaaa tacatgaact ttattcaaat attaattttg gaactggaaa
    38581 tattggctta acatcttctg tatatgtatt gataaatact ttgtatggaa atttatttaa
    38641 tatgattgat gcagaaaaaa tgtatttaaa tgtaaatcca gattttacaa aagattatgt
    38701 tttaggaaat ataaggatac atataaggcc aagaataaaa gctttattta atattataat
    38761 aatgattaat aaaattatga ataaaaataa aggaaataag gaaggtgata gtaatgagag
    38821 caacaggttc gatacagagt cttatggaaa caactcttga aacaattaaa ggttctatag
    38881 atgcaaatac tattatagga gaccctataa aaacagatac tacagtggtt gtacctatat
    38941 caaaggttac aattggcttt ggtataggag gaggagaata ctcaaaagga tatgatgata
    39001 aagataggga aattgaatta aaaaatgaaa aatcagatac gaattttgct ggaggtagcg
    39061 caggggctat atctgtacaa ccagtagcat ttgtagtagt tgaaagtgga gagactagaa
    39121 taatgagttt agatagtaat atcaatctag tggataatat attatctata actcctagag
    39181 tattggagaa aattcaaaat atatcacaaa gtaataagaa tcaagataaa aacaatatgt
    39241 aagaataaaa tatttttaaa tatgtatata gttttaagta aagtagtggg gttaatataa
    39301 atcccactat tttgttgtgt actttaaaca tttatatcta ataagatttt agtttaaaac
    39361 aatttaaata gataataaag ttgatatata gtataattat aaaaagaaaa gaagtattat
    39421 attatagata tataaacgca tttgagatat aagagggagt tataaatcat tagttttgag
    39481 gtgaatgtta tgagcgataa agaattatct attttgttgt tagaaagtat gaataatttt
    39541 cataatttaa taaagattat taataacgaa agatataaaa aagataaggt tcttacagaa
    39601 agacagttct ttgccttagt aaaaataaga aaacatgata aaatagagct taaaaatcta
    39661 agtagagatt tgcatgtatc tacttctagt ctgtgtatac tacttaataa attggttgag
    39721 caagagtatg tatataggga agaagatagt agagatagac gaaatacttt ttatggaata
    39781 actaaaaatg gagaaaagat attggataat gaaatactaa agtttgtatc tataataagt
    39841 gataaaatgg attgcctaga tatagataat aaagataaat tatttacttc tttggaagag
    39901 tctaaaaata taatagaaca attattttaa aaaggagaat ttattatgaa tataaagtat
    39961 tctaaagaga tattaaaaag tttagaaaat gctataacag tagtagctct atttgaggga
    40021 gaagatgttt ttacgacatt tgataaaata aatatgataa gcagaaattt taattctaaa
    40081 gaaaatagta tagatactgt aacattaatt gaaaataaca atttggtaaa tgtttgtttt
    40141 gttggttttg gtaagagaga gttattgaat agagaaaaaa ttagaatcat aggtgggaat
    40201 ttgtgtaaaa aattaaaaaa tatattgaaa aatgaagcat ataagagtag tgatgttaat
    40261 gtactgaatc ttaatttaaa tagtgatgaa ataggttgtt ttgtagaagg gatattactt
    40321 ggaaattata agtttgataa gtataagaca aaaagtaagg attttgaaag aaaagaagtt
    40381 gatactataa ctatatttac tgaaaaagaa gttgagtgtc aaatagaaaa ggctaaaata
    40441 ttagctaatt caactataat agctagaaat ctagttaatg aaccatcaaa cgtaatatat
    40501 ccaaaaacat tagcagtaga aacagttaaa cttggtgcag agtttgggtt taatgttgat
    40561 gtttatgaag aagaaaaaat aaaggcattg ggaatggatg cttttttcgc tgtttcaaga
    40621 ggttcaatta ataaaccaag attcatagta atgagatact ttggagataa agaaagtaca
    40681 gatatattag gtctagtagg taaaggattg acttatgata ctggtggata ttctttaaaa
    40741 tcaaatgctt ctatgctaga tatgaagaca gatatggctg gtgctgcgag tgttataggt
    40801 gctatgtgtg ctatatctca aagtaaatta aagaaaaatg ttatagcagt agtggctgca
    40861 tgtgagaatg ctttatcagg aggttcatac aaacctggag atataattag ttctatggca
    40921 aagaaaacta ttgaagtttt aaatacggat gcagaaggta gacttacatt agctgatgca
    40981 atatactaca ttataaacaa tgaaaaagta acaaaggtgg ttgatgtagc tacattaact
    41041 ggtgctgctt taacattgtt aggtaatgtt gcaactccta tagtaacaaa taatgatgat
    41101 ttttattgtg aattagaaaa agctgccact ttatcagggg aaagggtatg gaagatgcca
    41161 atttatgatg aatttaaaga tatgataaaa ggagaagaag cagaccttaa aaacactggt
    41221 ggtaaaaatg ctggatgtat aacagcagga gcttttattg gtgaatttgt tgggaatact
    41281 ccttggatac atatggatat agcggggaca agtacatcat caaaatcaat tggatacaaa
    41341 gcaaaggggg ctacaggaga acctgttaga acattgtact atttggcaga aatctaaaaa
    41401 acaattataa aatataattt ataaagccac gtggatattt ttgtaattta agattatcta
    41461 tgtggcttta ttttttattt aagtaaatta tttactcttt ttcttttttt caagtataaa
    41521 agtatctcta ttaaataaaa gagcaggtat gtacataata ctagtaacaa aaataaacgt
    41581 aaaaatagca gttatgctat gacttaaaaa accataatag tacctagagt tggtaaatgt
    41641 gtttagtaaa aatatgaatg aaaaataaat aaaacatata gctaagttat ctctaagtgc
    41701 atatctgtta actctaaatt ttctaacatc aaccatatat atatctgcat aaattatcaa
    41761 gcacttagag aagataaaga taaaatatat taagctagga aattcatagc ccaagttttt
    41821 agaaaaaatg agttctccaa ctgaacaaac taaactccaa gaaaaaaata tattaaaaag
    41881 atgatactgc ttaaaaatta gtatggctat acacagatat atacaaatat aattgattcc
    41941 aattggtaaa gagtttagag tactataatt acctgaagaa ataagtaata attgctctag
    42001 agccataatt attacaagta atgtacaaat tatcttctca actgtatagc tataaggtaa
    42061 aatatttttg gttagttttg gacaatagta taaaaataat ccaaatataa agagacttac
    42121 aaattgttca ctagaaaaaa gaaaaatttt aaacatataa cattctctcc tataataaat
    42181 ttaatatgta tctatataaa tatattcatt atatctcaat ttaatatata aaaaagataa
    42241 taatagttag attttttata tgaattttaa taggtaaaat atcctattgt tttgtagata
    42301 tatcctaatt atgtcaaaaa ataaaaaaat ttttatttat tagagttttt ggaaataata
    42361 ataacagata ttataattaa ttaacagttt ttgtaagtat ttgacaatag agagggtgta
    42421 acaaatggga ataatagagt cagcatcaaa attggctgag atggttcatt tattggctgt
    42481 tgaaaagggg ataactgata tagaagcatg ggatgaagct gtgaaagaat acagcaaaat
    42541 ttatgaagaa agaagaaatg aatagaatga taaaaaatga aaacttgatg ataaaaaata
    42601 actttattta aagaaattca atttttatag aagtattaaa aataatataa ataaaaagat
    42661 ggtatttcaa atgtaagtaa aaaatcattt tgggatacca tccttattat ttattttaat
    42721 aatatataag taataaatct tacttatcca tattttttat gtaacctctt ttttctagct
    42781 tttttatatg ctccttacgt atttcatcaa gattaatacc atattgttct tctagcttaa
    42841 acatcatagt aacacatgtc tgcgctacat ccattagttc cttagcagtt ttctttataa
    42901 tatcaacttc atctaaatca ttattttctc cacttagatt tctgaattta cctatacatt
    42961 cagctaattc accttgttct tcacccattt tgataaatgt agattctagt gttgggtcta
    43021 aattattaag ctctggtaaa gatatagttt ttagtttcat aaaagctcct ttcaagttat
    43081 tcgtatttat actaaaacat cataacaaaa ataatactaa aaaaaaactt taaattcaac
    43141 ataaaaactt acatatataa taaaaatcgt gaaataaatc tatatttgtc ttaatacagc
    43201 ctcatataaa acttctccaa taggtttatt tattacaaga gaagctgact tatcatagac
    43261 tgtatttgct ttattaataa gagcaatata atcacctttg taataatcta taaaacttgc
    43321 tgctgggtac acagctaatg atgtacctcc tataatcaat aaatcagcat tacttatagc
    43381 agaaattgtt ttagtaatga catcactgtc aagagcttcc tcataaagta ctacatctgg
    43441 ttttactata gaaccacagt tgtcacagta aggaatatta cctcccagat ttaacataga
    43501 ttctaagtca aaaaacttac cacatttagt acaataattt ctatgtacag aaccatgaag
    43561 ttctagcaca tttttacttc cagccatttg atgaagtcca tcaatatttt gagttatgac
    43621 agctttaagc ttacccattt cttcgagttt tgctaaagct atatgagcat tattgggttt
    43681 tgcattagga tatattaatt tatccttata aaattcaaaa aattcttctg gatatctaac
    43741 aaaaaaagta tgtgaaacta attgttcagc agtaaattgt ttattgagtt tttggctaaa
    43801 taatccagta gaacttctaa agtctggaat attagattca gttgaaacac ctgctccacc
    43861 aaaaaataca atattattgt gattagctat taagtctttt aagctatttg catccatagt
    43921 tacacctcca aattattata tataaattgt actacatatt aggtcgttta tgttttatta
    43981 atttaaataa atatatagtt taataagtta aataaaggga atataaataa aatgtataca
    44041 gagtataaat agacaatatt tactaaaata acaagttgtc gtataattat attaaaattg
    44101 ttttagtgta taagaagggc gggggaagta cgtgaagaaa aaagcagctt tagcaacatt
    44161 ggctatgtta cccttaggtg tggtaaatgc acatgctgat ggagatatag gtatagtgac
    44221 tataaattat ttaaatgtaa gaaatgaacc aactgccgaa agtagcatag cctttgttgc
    44281 taaaaaagat gataaagttt tgattaaaga ctcttctaat ggatggtata aaataaaagc
    44341 tgaatctgga caagaaggtt gggcttcatc aaaatatata gcaaaatcaa atagtgactc
    44401 tttaagaacg tctacaaata aagaaaaaca agttatttca aatagtttaa atatgagaaa
    44461 tggagcaggt acaagttaca gagtaataac tgtactaaaa aaaggtcaaa aagtagaagt
    44521 aatatcagag agtaatggat ggtctaaaat caaatatgat ggaagactag gatatgtatc
    44581 tagctcttat ttaggagacg tttcaaactc aactaataaa tcaaaaacta aacaagtgaa
    44641 tacaacttca ctaaatgtaa ggagtggacc aaatacaagt tatggtttgt taggcaagtt
    44701 gccaaaagga agtaaagtag aagtaatatc agaaagtaat ggatggtcaa aaataaagta
    44761 taatggaaaa gatgcctatg tatctagtat gtacttatcg gatgtaagtc aaagtaattc
    44821 agacaattct agtcaaagca atgataaaaa gaatactgat aaggttgtaa atacagcttc
    44881 tttaaatgta agaagtggac caggttctac atatagtaag ttgggaaaag tttataaagg
    44941 aagtaaagta actgtactat cagaaagtag tggatgggct aagattaatt ttaacaataa
    45001 agaagcattt gtagtaggca attatttatc tacttcagca gatacttcaa ataataactc
    45061 aaatagtaac tctgataaca gttctaatag taatggcaat aattcttcat catcaggtca
    45121 agtaaatggt atgtcaggta taagtggggc taaaattgat tataaatctt tgagttatac
    45181 tttagaatct catataagta aacaagttga gaaagcagca tcaggaggaa atgtgatagc
    45241 tccaagtaat aggaaaagca ctccaagtcc tgaatttagt actttttcag ctcaaagaac
    45301 aagctcattt gtaaatgcaa gttcaagtga tatagaatat tatttaaatc ctaagaattt
    45361 tacaaatact actaaaggta tgatgcagtt tttaaagatt aacagttata gagatggtat
    45421 ttcagaatca agtcttaact cgtatcttaa tggtttatct tctagtgtat ttaaaaacca
    45481 gggagcagcc tttataaatg ctgccaagaa gtataatata gatgttgtat atctagtatc
    45541 tcatgctatg tgggaaactg cttatggtaa gtctacactt gcccaaggtc aaacattaac
    45601 atcttataag ggacaacctc ttagtaagcc agttaaagta tacaattttt ttggtatagg
    45661 agcaatagat aaaagtgcta atgtttcagg tgcagaagca gcgtattcca atggctggac
    45721 tagtgtagaa gctacaatag atggctctgc aaagtggata tcacaaaatt acgtaaatag
    45781 ttctaagtac aatcagaata ctatttacaa gatgaagtgg aattatgatt atacatggca
    45841 tcagtatgca actgatgtaa actgggctaa tggaatttct ggaattatgg aaaatttaat
    45901 tggtctttat ggaggaggaa gtagtttggt ttttgaagtt cctcaatata agtaatacat
    45961 aaataaaaaa tatagactat gggtagtttt cattttattt aaattatcta tagtcttttt
    46021 gtatataatt tataatctgt aaatttaatg ttaacaaaac ttttatgtta taatattaat
    46081 tctaagtaaa tataagtgag taatgggtag aaatagataa aaagtggtaa taatatatat
    46141 aaagataatt ttgagaaagg aggatatata tggaaagtat taaggaatat ttggataagt
    46201 tagaaattaa taatagtggt cttggaaagc aacttaaaga agtttatata aatagagtag
    46261 tttattttaa ggaagataag atagtttatt tttatctaac ttctaaagat attgtttctc
    46321 atgaactttt agataaattt aaagaagaat tgatgtataa actcgattat tttaaagata
    46381 tgaggatgaa gataagattt actggtcttg aaagaaaatc caataaagat gttataaaaa
    46441 aatattggaa taatatattg tatatattaa agtatctttg tccatctatt gcagggtggt
    46501 ataaacaagt agaatttctt tgtttagaag aagaattaaa aataaaactt ccaaaaggta
    46561 tattttatga gcgattaatg aaaaaaaatg taacttatgt acttaaaacc gtgcttagcg
    46621 aagagttggg attagattta aatataacaa tagaaaaagc tgttgatgaa aaggtaaata
    46681 aagaaagact cataagaatc aatgatagag aaatggaaga aaaaattagg gctttagaaa
    46741 ttggaaaagt taataactgt gaagaaaatg aagaggaaag ttatgtcatt aagtctgatg
    46801 tagatgaaaa tttaatctat ggagataatg caaatgctat gattgaaaat atagttgaat
    46861 taaatgcatc ttctggaaca gttgcagttg ttggagatat atttgatgtt gacactaaag
    46921 aacttaaaaa cggaaaaata cttatgatag cttcaattac agattatact agctcaataa
    46981 gctgtaaact ttttttaaca gatacaaata aggatggagt acttgaaaat gttaaaaaag
    47041 gagcatactt aaaaatcaag ggtgacatag tttatgatac atatcaaaga gaaattagta
    47101 tgatgattag tgggataaga aaagaaacta gaatagagag agaagataaa tcagaggaaa
    47161 aaagagtaga actccatgca catacacaaa tgtcttctat ggatgctatt tgttctgtta
    47221 aaaagcttgt agagcgtgca gccaaatggg gtcattctgc tattgctata acagaccatg
    47281 gtgttgtaca aggatttcca gatgctatga atgcaggtaa gtcaaataat ataaaaatac
    47341 tttatggagt agaagggtac ttggttgaag atgattctct cattatagag gatgcaaatg
    47401 ataaagaact ttcgcagaca tttgttgtat ttgacataga gacaactggc ttttctaata
    47461 caaatgataa aataactgag attggtgctg taaaaataga aaactttaag attgtagata
    47521 gatttagtga gttaataaat cctgaaaaag atatttctta taagatacag gaattgacag
    47581 gaataactaa tgaattaatt aaagacaagc caaccattga agaagttctt cctaagttta
    47641 tggaatttgt tggagatagt gtattagtag cacataatgc agagtttgat actggattta
    47701 tatcgcaaaa atgtagggaa caaggcttgt tatataataa caaaaaagta gatacactta
    47761 tgttagcaag agtaatgtta ccaaacttaa aaagacatag attaaatgtc gttgcaaaag
    47821 aacttggtat tcctctttta aatcaccata gagcagtgga tgatgctgaa gctacagcac
    47881 ttatatttaa taagtttttg cagatgctta cagaaaaagg tgcaaaaact ctaagtgatg
    47941 taaacaatat acttggaaag attgattaca caaagcttag cacaaatcat ataaccttga
    48001 tagcaaaaaa ttctataggt ataaaaaatt tatataaaat aatttcagat gcacatgtaa
    48061 atcatttttt tagagcacca agaatcctta gaagtgtatt aaatgaatat aaagaaggat
    48121 taataattgg ttcggcttgt gaagctgggg tggtttttca agctgtaaag aaaaacgtgt
    48181 ctgatgagga aatgaaaaaa ataatagatt tatacgatta tattgaagta atgcctatag
    48241 ataataatag atttatgatt gataaaggag aagtaaagga cgaagaagag ttaagggagt
    48301 tgaataggaa attaattgat acagccaaaa aatttgacaa aattccagta gctactgggg
    48361 atgttcattt tttagacaaa catgaagctg tcttaagaaa agttcttaaa tattctcaag
    48421 gttttaaagt agatgaagaa gaaacttatt tacattttag aacaacagat gaaatgttgg
    48481 aagagtttag ttatcttgga gaagaattgg catatgaagt tgtagttgaa aatagtaatc
    48541 tgattgccga tatggttgaa gatataaaac ctataccaga tgatacttat cctccaatta
    48601 tagagggctc agatgtggag ttaagagaaa tgtgttacaa aaaagccaaa cgaatctatg
    48661 gagacccaat accagaaata gttcaaaaaa gactggatag agaattaaat tcaataataa
    48721 gcaatgggta tgcagttatg tatattatag ctcaaaaact ggttgcaaaa tctctttcag
    48781 atggatattt agttggttca agaggctcag ttggctcatc ttttgcagct actatgagtg
    48841 atataacaga agttaatcct cttccagcac attatatttg tgaaaacgaa gactgtaaat
    48901 attcattctt ttatgaaata ggtgaatggg gctcaggtgt tgatttacca gacaaggatt
    48961 gtccaaagtg tggaagaaaa cttgctaaaa acggtcatga tattccattt gaggttttct
    49021 taggttttga aggtgataag gaaccagata tagacttaaa tttctcagga aattatcagc
    49081 caacaattca taaatacaca gaagaactat ttggagaggg gtatgtatat agggctggga
    49141 ctataggtac tgtagcagaa aaaacagctt ttggatacgc aagaaaatat gtggaagaaa
    49201 ataatataag tgtaccaaat gcagaagtac ttaggctttc aaatggatgt actggagtaa
    49261 aaagaacctc aggacaacat cctggtggag ttatggttat accagactat aaagatgtat
    49321 acgattttac acctatacag tatccagcaa atgatacttc ttgtggtgtt ataactactc
    49381 actttgatta tcattcaata agtggtagaa tacttaaact tgatatactt ggacacgacg
    49441 gtcctaccat tataaggatg cttgaagata tgactggaat aaatataaca gaaattcctt
    49501 tagatgataa agagactatg tctctattta catctacaga agcattaggt gttacaccag
    49561 aagaaataaa ctgtcctata ggttgccttg ctgtaccaga gtttggaact aagtttgtac
    49621 gacaaatgtt acttgacaca aaacctacta catttgcaga acttgtacgt atatctggtc
    49681 tctctcatgg gacagatgtt tgggtaaata atgcacaaga cttagttaga gaagatatag
    49741 ttggattaaa agatgttata tctacacgag atgacataat gaactattta atatttaaag
    49801 gattacctcc caaaatgagt tttacaataa tggagagcgt aagaaaaggt aaaggtttaa
    49861 aaccagaaca cattgaagaa atgaaaaaaa ataatgttcc agaatggtat ataggctcat
    49921 gtaaaaagat aaagtacatg ttcccaaaag cacatgctgt tgcttatgta atgacatcat
    49981 ttagaattgc atattgtaaa gttcactatc cagaagcatt ttatgcgact tattttacga
    50041 caaaagttga ggattttgat gcagatttaa ttgttaaagg attagatgct ataaaatcaa
    50101 aaataaatga aattgagtca ctgggaaatg atgcaaccac aaaagaaaaa ggtatgttga
    50161 ccgttttaga agttgctctt gaaatgtatg ctagaggaat aaaattatta ccagttgata
    50221 tatataaatc agatgcaact gagtttatag ttgtaggaga aaaaacatta cttccaccaa
    50281 tggcagcaat acaaggtctt ggaggaaatg cggctataaa catccaaaat gaaagaaaaa
    50341 atggtgaatt tatatcaaaa gaagatttga gaaagagaac aaaaatatca aaaacggtaa
    50401 tagaaactct tactaatcat ggttcacttg agaatatgag tgagagaaat caattgtcat
    50461 tgttttaagt tagcccaaaa agttgcaaat aaaagaattt tatgatatca tagtatagaa
    50521 aatagtatac tttgcagaaa ctaagagtga gacagctgtt ctcactcttt tattttaaat
    50581 atattattaa aaagctggtt tatttttatt aaatatattt tatttaagat tatataaact
    50641 ggtcatttac aattgaatag gaggaacttt aatgaaaaaa aatttagaag ctacaattga
    50701 ggagattgta actaaaataa cggatgaaca tggatttgaa atggttgatg ttgaatatgt
    50761 aaaagaagca ggagaatact acttaagagt atacatagat aaagaagaag gaatatcttt
    50821 aaatgaatgt gaattagtta gtagagaatt aagtccaata ctagatgaaa aagaccctat
    50881 aaaagaaaat tactttttag aggtatcttc tccaggactt gatagagcat taaaaaaaga
    50941 cagagatttt gttagatatc aaggtagaga tgtagattta aaattatata aaccattaaa
    51001 tggatgtaag caatttgaag gtgaacttgt aggattaaca gaagataata atataaaaat
    51061 cattgcaaat ggtaaggaaa tggaatttaa tagaaaagat gttgctattg tcagattagc
    51121 aataaagttt tagtggtata ttaaataggg aggatataaa aaatgaatca tgaatttatg
    51181 gaagcattag atgaattagt agttgacaga ggtatagata aagaaatact tatagatact
    51241 atagaacaag ctcttttaac tgcatacaag aaaaactttg gttcagcaca aaatgttaga
    51301 gttgaatttg atagagacaa gggagatata aaagtatttt ctcaaagagt tgttgttgat
    51361 gaatcagatt tatatgatac tttcttagaa atagagttag cagatgctag agagataaac
    51421 cctaattatg aattaggtga tattatagaa catgaagtta cacctaaaaa ctttggaaga
    51481 attgcagctc aaacagcaaa gcaagtagtt gttcaaagaa taagggaagc tgagagagaa
    51541 atagtgtata atgaatttat agaaaaagaa aatgaaatag ttacaggaga ggttgctaga
    51601 gcaaataaaa atgttgttta tgtaaatctt ggaagaatag aaggtataat gactcaaagt
    51661 gaacaaatac catttgagaa ttataaagca ggtcaaaaaa taaaattcta tatacttgaa
    51721 gttaaaaaga ctaacaaagg acctcaaata gttgtatcaa gaagtcatcc gggtctagta
    51781 aagagattgt ttgaagaaga agttcctgaa atatatgaag gaatagttca aataaaatct
    51841 gtagcaagag aagcagggtc aagaactaaa atggcagtaa gatctataga tgaaaaaata
    51901 gacccaattg gagcttgtgt tggaccaaaa ggacttagag taaaaaatat agtggatgaa
    51961 cttggcgatg agaaaataga tataataaaa tatagtgaag acccagcaga gtttatatca
    52021 gcagcactta gcccatcaaa agttgttaga gtagatatag atgaagatga aaagtctgcc
    52081 ttagtaatcg ttccagatta tcagttatcg cttgctatag gtaaagaagg tcaaaatgca
    52141 agactagcag caaaattgac taactggaaa atagatatta agagcgaatc tcaagcagaa
    52201 caagaaatgt taaatcttga aaattccaaa gaaatagaag ctgaggatgt tgaagctgaa
    52261 tttatcgacc aagaagagtt agatacttca gaggataatt ttagtgaaga agagtaagga
    52321 gggatgattt tgaaaaaagt aaaaaaagtg cctcaaagaa aatgcatagc atgtcaagat
    52381 agagactcta aaaaagagct tataagaata gttaaaaata aagaaggaaa aatattttta
    52441 gacccaacag gaagagccaa tggaagagga gcatatgtat gtaaaagctc tgaatgtcta
    52501 aaaaaagcta taaagagtaa agcattaaat aaagctttta aaatagatgt tcctgatgaa
    52561 gtctatgata atctacttat ggagttagaa gaatatgaaa aataataaag aaaaagtact
    52621 ttcgttctta gggctcgcaa ctcgtgcagg gaaaatagtg tctggtgatg attcaacttt
    52681 gcttgacctt aaaaaaggaa aagtaaattt gattttaatc gcagaagatg catcaaataa
    52741 tactaaaaaa ctttttaaag ataaatcaac ttttagaaat attccatatc tatttttttc
    52801 aacaaaagag gaaataggat ttgcaatagg aaaatctcca agagcagttg taggaataaa
    52861 agatgaaaat ttttctaaaa agataattga actaatagaa atttaaaata aaataggggg
    52921 tgatcttgtg tcaaaaacaa gagtatacca aatagcagaa gaattaaata tatcaaatga
    52981 agagcttata aataagttag ctgaattaga tataaatgta actgacaaag attcagtatt
    53041 agaaggtgaa gagttagaat tagcacttga aatgttaggt gaagatttat ctcaagaaaa
    53101 tggaaatgtt atagaaatag atggaaagtt gacagtacaa gtattagcaa cgaaattaga
    53161 taaatctcca tcagaaataa ttatgaagct tatgaaaatg ggaactatgg caacaataaa
    53221 tcaagagata agttttgaga ttgctgcctt ggctgccaaa gactatggct ttgaattaac
    53281 agtagctgaa agtgatgata cagaagcttt agaaatagaa gctttaatgg aaattgaaga
    53341 agataaagaa gaggatttaa aacctagacc accagttgtt acagttatgg gacatgttga
    53401 ccatggtaag acatctttac tagatgcaat aagaaaaact gatgtgattt caggtgaagc
    53461 tggaggaata actcagcata taggtgcttc agaagttaaa atcaatggac acaaaatagt
    53521 atttttagat actccaggac atgaggcttt cacatcaatg agagcaagag gagcacaagt
    53581 tacagatata gcaatattag tagttgcagc agatgatggt ataatgcctc aaacagttga
    53641 agctataaac catgctaaag cagcaggtgt acctttaata gttgctatta ataaaataga
    53701 taaaccaggt gcaaacccag ataaggttaa acaggaatta gcagaccaag gattattagt
    53761 tgaagactgg ggtggagaag taatagcagt tccagtatca gctaagaaaa aagaaggaat
    53821 agatacactt ttagaaatgg tattattggt tgctgaaatg gaagagttaa gagctaatcc
    53881 aaataaaaga gcagtaggaa ctgttataga agctgagctt gataaaggaa gagggccagt
    53941 tgcaacagta cttgttcaag gtggtacttt aacagtaggt gacccaatcg ttgcaggtgt
    54001 tgcatgtggt aaagttagag caatgataaa tgcaaaaggt aagagagtaa aaacagcagg
    54061 accatctaca gcagttgaga tattaggtct atcagaagtt ccacaaggag gagaccaatt
    54121 tgtcgaagtt ccaactgata agattgctag aagtgtagca gcaagaagac aacaaatagt
    54181 tagagatgaa atgttaaaat caactcaaag attatcacta gatgctctat ttagtcaaat
    54241 gagtgaaggt tctataaaag accttaatat agttataaaa gcagatgtac aaggttcagt
    54301 acaggcagtt aaacaatctt tagaaaaatt atcaaatgaa gaagttcaag ttaaagtaat
    54361 acatggtggt gttggagctg taacagaatc agacatatta cttgcagcag cttctaacgc
    54421 aataataata ggattcaatg taagaccagt tccaggtgca gaatctctag gagaaaaaga
    54481 aaatgttgat ataagaacat atactataat atacaaggca atagaagata tacaagcggc
    54541 tatgactggt atgttagacc ctgaatatgt tgatgaagaa acaggaaaag ctgaaataag
    54601 agaaatatat aaaatatctg gtgttggaac agtagctgga tgttatgtga ctaatggtaa
    54661 gatatttaga aattgtaaag taagattagt tagagatagc ataataatac atgaaggtga
    54721 gcttgcagca cttaagagat ttaaagatga tgtaaaagaa gttaattctg gatacgaatg
    54781 tggtatgagt tttgtaaatt ataacgacat aaaagaaggc gatatagtag aagcttatat
    54841 aactaaagaa gtagaaagaa aattataaat tcgtatcaaa gaaaatcagt tagtaaagaa
    54901 ggtcgatggt atggcatcat ataatagaac aagaaggata gcagaagaaa taagaaaagt
    54961 cgtaagtact atgcttataa atggagtaaa agaccctaga ataacatcta tggtgagtgt
    55021 aactgatgta gaagttacaa atgacctaag atatgcttat gtatatgtaa gtattctagg
    55081 tggagatgaa gaatccacac taacaggtct taaaagtgct ggaggatata taagaagaga
    55141 agtaggaaaa aatataaaac ttagatatat tcctgagata gtatttaaac ttgatgattc
    55201 aatagaaaaa ggaatgtata tggatagcct tataaaaaga gttaatgaaa aaaatgctca
    55261 acaaaatgag gatgaaaatt atgatgaata atatggatag tattataaac tatatttatg
    55321 agggtgacta ttttatagtt acctctcata tcagtccaga tggagacaat attggttcta
    55381 cactttcaat gtattataca ttgaagaatt taggaaaaaa tgtatattat gtacttgatg
    55441 atgaagctcc attaaattta aggtttttgg ttgaaggtgt aaaaatctat aagtctaatg
    55501 aatttaatat gaagaactat tctctaattg cacttgattg tggggataag atgagaatat
    55561 gtgtgagtga tgaaatcaaa aataatgcat caaaattaat ctgtattgac catcatgcta
    55621 gtaatgattc atatggagat ttaaattatg tagatattga tgcatcttct acatgtgaat
    55681 tagtttataa tttattagtt agatttcagc aaataaaaga tattaatatt ataaatgaag
    55741 atatagcaac atgtttatat acaggtcttg taactgatac tggaaacttt tcgtattcaa
    55801 atgtacatgc aagtagcttt gaaatggcaa aaaatttact tgttttaggt gcacaaaaaa
    55861 atactataat acaaaatata tatcaaagca attcttctgg ttattacaaa ttattaggag
    55921 aagctctaaa gggtttggag atatttgatt aaaaaatagt tacgcacact cgtgacttta
    55981 gtcatgagtt agtagctaaa atagtcagca tatagggaaa cttatatgta gagataggat
    56041 a
//
LOCUS       DAMJXI010000019        54981 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.020, whole genome shotgun sequence.
ACCESSION   DAMJXI010000019 DAMJXI010000000
VERSION     DAMJXI010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 54981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54981
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.020"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            532..1371
                     /locus_tag="PC465_001548"
     CDS             532..1371
                     /locus_tag="PC465_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HDF2648865.1"
                     /translation="MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTR
                     AEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGR
                     AKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTII
                     DAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGI
                     GVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGG
                     IFK"
     gene            1368..2549
                     /locus_tag="PC465_001549"
     CDS             1368..2549
                     /locus_tag="PC465_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648866.1"
                     /translation="MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVS
                     ISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVY
                     LKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSG
                     PRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLK
                     EKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKEDIDKISYIKTKPIDLADLANGE
                     EKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNMDNPNVISDV
                     DIKVVVESTEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEV
                     E"
     gene            2853..3755
                     /gene="ptb"
                     /locus_tag="PC465_001550"
     CDS             2853..3755
                     /gene="ptb"
                     /locus_tag="PC465_001550"
                     /EC_number="2.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate butyryltransferase"
                     /protein_id="HDF2648867.1"
                     /translation="MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANA
                     ILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTS
                     IILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENAC
                     TVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNA
                     VSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIIL
                     TSRADSEETKLNSIALGVLMAAKA"
     gene            3777..4856
                     /gene="buk"
                     /locus_tag="PC465_001551"
     CDS             3777..4856
                     /gene="buk"
                     /locus_tag="PC465_001551"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HDF2648868.1"
                     /translation="MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYE
                     KVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVG
                     VLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALN
                     QKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERS
                     GGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLV
                     YEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGE
                     DEMIALAQGGLRVLTGEEEAQVYDN"
     gene            4846..5523
                     /locus_tag="PC465_001552"
     CDS             4846..5523
                     /locus_tag="PC465_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2648869.1"
                     /translation="MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLD
                     VVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGG
                     DNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLI
                     NNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKL
                     YMREDWM"
     gene            5566..5781
                     /locus_tag="PC465_001553"
     CDS             5566..5781
                     /locus_tag="PC465_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2648870.1"
                     /translation="MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPAT
                     VFEMEKCIGCASCATMCPDVVITVERD"
     gene            5810..6889
                     /locus_tag="PC465_001554"
     CDS             5810..6889
                     /locus_tag="PC465_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HDF2648871.1"
                     /translation="MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELP
                     KIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVL
                     NVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYY
                     RSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEV
                     LEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKA
                     GLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGM
                     TPTPAEIVEKAKKIIAGELVAGGAR"
     gene            6889..7641
                     /locus_tag="PC465_001555"
     CDS             6889..7641
                     /locus_tag="PC465_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HDF2648872.1"
                     /translation="MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDA
                     VGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGT
                     AEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRV
                     SEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWG
                     LAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK"
     gene            7642..8199
                     /locus_tag="PC465_001556"
     CDS             7642..8199
                     /locus_tag="PC465_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HDF2648873.1"
                     /translation="MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEM
                     RGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKE
                     KVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
                     KEKFVPLNREALQKGMDATCSKATN"
     gene            8369..9715
                     /locus_tag="PC465_001557"
     CDS             8369..9715
                     /locus_tag="PC465_001557"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HDF2648874.1"
                     /translation="MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVV
                     VGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHN
                     PVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCLPIGENVGRKLHEHCAQRDYV
                     DYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSLPDGNNINYKCGS
                     THPEQLQRAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLA
                     QDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLD
                     YNTTGDGVLSSLILANIILQEKKPLSEIASIMSQYPQVLVNATIKNENKNKYMEYPEI
                     KTEIERIESILDGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATDLANLIQEKLS"
     gene            9982..11814
                     /gene="glmS"
                     /locus_tag="PC465_001558"
     CDS             9982..11814
                     /gene="glmS"
                     /locus_tag="PC465_001558"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003401499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HDF2648875.1"
                     /translation="MCGIVGYLGSRKAAEVIVEGLSKLEYRGYDSAGVAVNSSNEKEL
                     NIRKFKGRLSVLAEDLEKNPIDGNLGIGHTRWATHGEPSDVNSHPHFNQAKTIAVVHN
                     GIIENYMEIKEELISEGVKFESQTDTEVIAHLVDKYYEGNLLDAVYKTISKLRGAYAL
                     GVICKEHGNELVAVRKDSPLVVGVGEGENFIASDIPALLKYTRDVYFLENGEVVHLKD
                     ENVTVYDSNRNLVEKEVFHVTWDVEAASKGGYDYFMSKEIHEQPTGVRETLERRLDDN
                     GNIILDSINISKEDLEKINKVYIVACGTAYNAGLLGKYAIEKFVNIPVITDIASEFRY
                     SDPFVDENSLVILVSQSGETADTLAVLRDSKAKGARILSITNVVGSSIARESDDVFYT
                     WAGPEVAVASTKAYTTQITSLYMIALDFAIKKGTITREFYDSMISKMKEIPSKIQEIL
                     DNEEYIKEVAKTVVSSEHAFYLGRGIDYSLAMEGSLKLKEISYIHAEAFAAGELKHGT
                     IALIEKGTPVIAIATQEKLFEKMVSNMEEVRARGAYVVAIAQSHNKDVEKAADKIIYI
                     PNSDDILSPILAVVPMQLLAYHVSVLRGCDVDKPRNLAKSVTVE"
     gene            12266..13561
                     /locus_tag="PC465_001559"
     CDS             12266..13561
                     /locus_tag="PC465_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase"
                     /protein_id="HDF2648876.1"
                     /translation="MTNDFKKEKKEDYFVNLKAISTEVLQEKVQDNAWVIVDTRLNDA
                     YNGWKLDGVRRGGHIKGAVDFSANWLSVYLDRKDEVLEQALKTKRIDLDKNIVLYDAN
                     GKDALVVADYLSKKGYKYLYKYDIKQWADDENLPMERYKNYQMIVPAFIIKDILDGKI
                     PETFEDSKNIKMIEASWGEESYTKGHIPTSVHVNTDIIEPPPTWMLDNDDNLTKFALD
                     YGLTKDDTVIVSSSTPMASYRLAVILRYIGVKDVRVLNGGTNSWLSAGYELEFISNPK
                     HSCTNFGADIPVNSQLVVTTSELRQKLKEKNKFILVDNRTWDEHIGKVSGYTYYDKKG
                     RIPGALYGHSGSDSVSLEEYRNIDNTMRNKYEILEMWDKENIDVNKQLIFMCGSGWRA
                     AEVLTYANVIGVENTSLYSDGWMGWSLDNSNLIEVGEHK"
     gene            14038..14775
                     /locus_tag="PC465_001560"
     CDS             14038..14775
                     /locus_tag="PC465_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwmB family TATA-box binding protein"
                     /protein_id="HDF2648877.1"
                     /translation="MKKVKLAISFFILMIIGMTISYADTSINTRYNRLSKALEISEAN
                     FKFYNVKINSVINHNLSNKEFHNIFIEIINNLKLDKKGINWNQKGSGDKIQLCATIKG
                     SDKEISIKGINKNNKESYIVVDILDNKVYKHKEVIYSNVENVLNKYSSQVDVSACIVG
                     EYTKRLQNNKYDDILQKILYNMSAKQIDEVKDVNFLSITAYSKVLNDYELEYLGEKIN
                     LNIGIKYNEDDGKTLIYIATPIIKLDY"
     gene            14796..16049
                     /gene="murA"
                     /locus_tag="PC465_001561"
     CDS             14796..16049
                     /gene="murA"
                     /locus_tag="PC465_001561"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDF2648878.1"
                     /translation="MAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGV
                     PNLRDVHVISDLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLL
                     ARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGNKLYLDF
                     PSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGV
                     KELKGAEHNVIPDRIEAATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEM
                     DNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHV
                     AEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIY
                     HIQRGYVDIDKKITALGGQIEIVED"
     gene            16136..17200
                     /gene="spoIID"
                     /locus_tag="PC465_001562"
     CDS             16136..17200
                     /gene="spoIID"
                     /locus_tag="PC465_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein D"
                     /protein_id="HDF2648879.1"
                     /translation="MKNPLVVLLGFVTCSVLVPSLITLVSYKNVELTEKPESPVSINK
                     TIKKSDIEDKGNKEEKNTVNYETVNKKAPIINVYNHITGKTEKMDMENYLCGVLAGEM
                     SSEFDIEALKAQSVAARTYVVYKQEHGKSSKHKNAVVCTDYKHCQEYKSYDTLKKLNG
                     EEWIKNKYSKIQEAVRGTKGQIITYNDKAILPLYFSTSSGKTENSEEVFSAKYPYLKS
                     VESPYDKYSPKFASTLKISNTDFVKSLRRAYSTIVIDVNNLSKQVSITKRSDAGTVEK
                     IKLGNKELTGKDIRTVFKLNSANFDIKFGEGYIDFVVKGYGHGVGMSQWGAEGMAEEG
                     YKYYDILSHYYTDTKIKDIY"
     gene            17266..17934
                     /locus_tag="PC465_001563"
     CDS             17266..17934
                     /locus_tag="PC465_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HDF2648880.1"
                     /translation="MKKKLLEKDGFYLSLFVCVCLLAVGGVWFTNNNVDKLASNKGIM
                     ENANKDSEEEIHLIEKDKKDAIPTATDSKQNLEKAKSKEENKSSTTKLNYIGDKVIRG
                     YSEKEPSYSKTLDVWETHKGVDISCTKGKEVKSLLNGIVVDVFDDEEYGQSVKIKSDN
                     NIVVVYSNLDKNVSVKKEQKVTEGQSLGTVGSTSQIESEEGIHVHLEAYSGEKSIDPM
                     SLIK"
     gene            18032..18292
                     /gene="spoIIID"
                     /locus_tag="PC465_001564"
     CDS             18032..18292
                     /gene="spoIIID"
                     /locus_tag="PC465_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcriptional regulator SpoIIID"
                     /protein_id="HDF2648881.1"
                     /translation="MRSHIEERAIVVAKYILEKNTTVRQTAKTFGVSKSTIHKDVTER
                     LKEINPSLAKEVKNVLDKNKSERHIRGGLATKLKYEKENKKM"
     gene            18489..19508
                     /locus_tag="PC465_001565"
     CDS             18489..19508
                     /locus_tag="PC465_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HDF2648882.1"
                     /translation="MAGADIGIDLGTANVLVYVSGKGIVLEEPSVVAIDKRTDSVLAV
                     GEEAKKMIGRTPGNIVAIRPLRDGVISDYDVTEKMLKSFIDKIVDKKGFGRFFMPRIM
                     VCVPTGVTEVEKRAVEDATRQAGAREVYIIEEPIAAAIGAGVDISQPNGNMIIDIGGG
                     TVDIAVISLGGAVVSESIKVGGDRFDDAIVKYMKKQHNLLIGERTAEKIKFEIGSAFK
                     REEEKYMKITGRNLITGLPSSITINSTEMLEALRECVEQIVVATHAVLEKTPPELAAD
                     IGDVGIIMTGGGSLLYGLDKIIEQRTGITVTIADEPLSCVAKGTGIALGSIDLLETGG
                     SFKRK"
     gene            19524..19952
                     /gene="fabZ"
                     /locus_tag="PC465_001566"
     CDS             19524..19952
                     /gene="fabZ"
                     /locus_tag="PC465_001566"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HDF2648883.1"
                     /translation="MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNVTVNEPF
                     FQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDT
                     LTMEVEMTTLRKNIAKADAKAYVGEELVCKGELMFALVEK"
     gene            complement(20063..20572)
                     /gene="yyaC"
                     /locus_tag="PC465_001567"
     CDS             complement(20063..20572)
                     /gene="yyaC"
                     /locus_tag="PC465_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HDF2648884.1"
                     /translation="MYLAKVNYSDDDVIQMLSSVLKTIINENTIVVCIGTDRAIGDTL
                     GPLVGTILKNSNFKYPVYGTLDNPIHALNIYESLDTIKNTHIQGNFLAIDACLGSQSN
                     IGNIQIREGPILPGKGVGKKLPQIGNYSIVGIVDKIDENNKLSFNNIRLSFILDLAET
                     IALALLVST"
     regulatory      20761..20864
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            21001..22194
                     /locus_tag="PC465_001568"
     CDS             21001..22194
                     /locus_tag="PC465_001568"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HDF2648885.1"
                     /translation="MARHLFTSESVTEGHPDKICDQISDSILDALLEKDPQSRVACET
                     TVTTGLVLVAGEISTSAYVDIPKLVRETVREIGYTRAKYGFDCDTCAVITSIDEQSGD
                     IAMGVDEGLESKTGEEIEEEIEKVGAGDQGIMFGFACNETPELMPLPISLAHKLSRRL
                     TEVRKTGLVDYLRPDGKTQVTVEYEGSKAVRVHTVLISAQHCETVSNDKIREDLINHV
                     IKEVIPAELLDEETKIYINPTGRFVIGGPQGDTGLTGRKIIIDTYGGYSRHGGGAFSG
                     KDPTKVDRSAAYAARYVAKNIVAAGLADKCEIELAYAIGIARPLSIFIDTFGTGKVSE
                     EKLVELVNKHFDLRPGAIIRDLDLRKPLYKKVAAYGHFGRTDIDLPWERTDKVEQLRK
                     DALGE"
     gene            22510..23607
                     /locus_tag="PC465_001569"
     CDS             22510..23607
                     /locus_tag="PC465_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648886.1"
                     /translation="MSGKVNIKTVISFAGAYVATVIGSGFATGQEILQFFTFYGYAGI
                     IGGIISMVLFSWFGAEVIDKGRELKLKEPIKIYQVYCGKYLGTFFEWFGPLFLFGTLV
                     IMIAGAGATLSEYYGLNPYVGRIGMAIVSLITVSLGLTRLSKILGNIGPIIIIFTLLV
                     GAISLFSNIDALSNAGNMVDSLNIKTATSNGYFSGVLYTCYNVIIVITFLTGMGASAV
                     NKKDAVWGGIVGGVALMAAAIMMNLALLSDIGNIYTKEIPALYLADKISPIIGILFSV
                     VLLLGIYTTAVPLLWSVTNRFVEDDHPKFKIITIVVSILACIGGLLPFDKLVGTLYPY
                     TGYMGILILLCMLYRRITKTEGYKENKSEIS"
     gene            23871..26090
                     /locus_tag="PC465_001570"
     CDS             23871..26090
                     /locus_tag="PC465_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HDF2648887.1"
                     /translation="MEKLEGMISEIVFKNEDNGYTIAHLVNENDEIVVVGCMPTLAIG
                     ESIEVEGKWVNHKIYGTQFEVNSFMPVTPSSLEGIYVYLSSGMIHGIGEKMAKRIIDK
                     FGVDTLEVIQNSPEKLQEVEGIGSKKVKQIVKSYEEDRELRNIIIQLSPFGITPNYCL
                     KIYKKYKSSAIEVINKNPYQLAEDIRGIGFKVADSIASKIGIDKNSKDRICQGILYTL
                     NKSLSNGHTYLPEHVLIQDSEKLLELNGEILKECVMMLVYNQKIHIEKVNNENLIYLM
                     PYYLAENGVCSQIVKLSQYEFEDLKIDIDNEINVLEEDKKIKLAEKQILAVKESVNSG
                     VLIITGGPGTGKTTTINTIIDIFENNGKSVTLAAPTGRAAKRMSETSNKEAKTIHRLL
                     EMGFSTDDDLTFFKDEEDPINSDVIIVDEVSMVDIILMYNLLRAIKLGTRVILVGDSD
                     QLPSVGAGNVLKDMINSNIINVVKLNEIFRQAQESMIIVNAHKINNGEPLYLNTKGKD
                     FFFIRKSTNEEILNEIIGLVNERLPKFYKVEKLKDIQVLSSMRKGELGVTNLNIELQK
                     YLNKKEKFKVEESFSKRLFRVGDKVMQVKNNYTKKWETEDQKESGEGIYNGDIGYVYH
                     IDKDKKTIYILFDQTKIVSYLYDELDEIDHSFCTTIHKSQGSEFPVVVLPIAWAPPML
                     LSRNLLYTAVTRAKKLVVLVGDVKYLEYMIKNNRVNQRYSNLGYKLNKFKQEGLLIE"
     gene            26093..26875
                     /locus_tag="PC465_001571"
     CDS             26093..26875
                     /locus_tag="PC465_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HDF2648888.1"
                     /translation="MKICNDNFIKNFKNMINKCLDFIYPENISCIICDKSIKKTNTYS
                     ICKSCFKEMNFIQDGCMKCGKPIIRHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDV
                     TKKMVLGLKYNQKTFMAKYIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQK
                     IAFNLSKIVNIPLLDCISRKKYTRMLYKLNKKERKEELKNVFVVKENVKLINNKNILL
                     IDDIFTTGLTTNEISKLLKLSGANKVFVLTLLTKANDNYIME"
     gene            27207..29120
                     /locus_tag="PC465_001572"
     CDS             27207..29120
                     /locus_tag="PC465_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2648889.1"
                     /translation="MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKY
                     IDEWLSTFCNAYIKRKPNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLL
                     LCNNKKVTLNDLSNKLYINKNIVREEISKLSVALNNYNLNISTKKGSGIYIEGDEKDI
                     RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMLTIEEDMDIRLTDISFKQLML
                     FLLINIIRIRLGNSLKVSNTKKELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLIL
                     GMNKQINSNNIKKSLYLNEELASYTKKIINLVSEESGINFNNDILLYEQLICHLNVTM
                     HQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEDEIGYLTLHFQTSLE
                     RKYSKRESNKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTID
                     FIIAFQEYENIQKPIFITTPLFTDEDENKLKEFTNKIKEKDTSYKLMNRLMMSDYLIR
                     ELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDMKYIK
                     QSVLCFARLKTPIKIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDIL
                     SKCDIEKVKDILI"
     gene            29261..29569
                     /locus_tag="PC465_001573"
     CDS             29261..29569
                     /locus_tag="PC465_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2648890.1"
                     /translation="MEEIVLKIIIHAGNAKSMLYEALDYAKENDFKKADELIENANEE
                     ILKAHKVQTELIQKEAGGDKSDISILLIHSQDHLMTCMSERNLIKEMIMLRKEIQKLK
                     "
     gene            29592..29918
                     /locus_tag="PC465_001574"
     CDS             29592..29918
                     /locus_tag="PC465_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2648891.1"
                     /translation="MKRKVYLFCSFGMSTSLLADKMQKVADEHNLPIEVEAFPIAEID
                     KIVEEKNPDCILLGPQVKYMLKELKPKFEAQGKLIDIINEVDYGTMNGEKVLKLAIKL
                     IKSKQA"
     gene            29957..31291
                     /gene="celB"
                     /locus_tag="PC465_001575"
     CDS             29957..31291
                     /gene="celB"
                     /locus_tag="PC465_001575"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HDF2648892.1"
                     /translation="MNRLERILMPLAEKIGKNKLLIAIRDGFLVSSPLLIIGSLFLLV
                     ANFPIKGWNEFVGQIFGPDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIAS
                     AAVAIVAFFIITPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
                     VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGSIHEFIFKFL
                     QMPLLKLGNSLGAMAIAYIFLHLFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGS
                     KIPNIITGQFQDMFATFGGAGSTLSLVIAMLLICKSKRIKSMGKLSILPGIFGINEPL
                     IFGLPIMLNPILLIPFAIVPTINIIIAYFCMSAGLVPLTNGVQLPWTTPIIFSGFLTT
                     GWQGAVLQLVLLILGIFMYIPFIKMLDKQYLREENETVEEEDDDISFDDLVL"
     gene            31302..31820
                     /locus_tag="PC465_001576"
     CDS             31302..31820
                     /locus_tag="PC465_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/betaine/sarcosine/D-proline family
                     reductase selenoprotein B"
                     /protein_id="HDF2648893.1"
                     /translation="MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGVMMEQFLNE
                     SKVIATLFCGDEFFVNNQEEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKN
                     INDKTDIPAFAAMSEENIDVINEYKNDICIVKTPKKGGIGLNDSLNNICKLAKAIANK
                     EDITLMKEEFCY"
     gene            31916..32875
                     /locus_tag="PC465_001577"
     CDS             31916..32875
                     /locus_tag="PC465_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase"
                     /protein_id="HDF2648894.1"
                     /translation="MWGMIATWRMALEGITEASEHLEKGMEAGDAVELAVRRVEDYPF
                     YKSVGYGGLPNENCEVELDAAFMDGNTLDIGAVAGIRDYSNPVSIARKLSYEKVNNFL
                     VGIGAEDYAHKNGFERKNMLTDRAKLHYKKRKKETLDKGLSPYAGHDTVGMISLDKTG
                     KMCAATSTSGLFMKKRGRIGDSALSGSGFYVDSSIGGATATGLGEDLMKGCISYEIVR
                     LMKEGKHPQEACDIAVNELDKQLIKRRGKAGDLSLVAMNNKGEWGVATNIADFTFSVV
                     TKEESPTVYISNRVDGKTIHKVISNEWMEAYEARIKAPIEVSE"
     gene            32924..33976
                     /locus_tag="PC465_001578"
     CDS             32924..33976
                     /locus_tag="PC465_001578"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HDF2648895.1"
                     /translation="MNIISNKIDELKEDLLSDIIDIVKIPSVKGESENGFPFGEKVGE
                     ALNKALEISEKLGFKVRNLDNYIGYAEHGDSDDYVCVIGHVDVVHEGDGWKHQPYKGE
                     ETNGRIYGRGVLDNKGPIMSALYGLYAIKELNLKLDKRVRIIFGTNEESGFEDIPYYL
                     EKEKAPIMGFTPDCKYPVVYGEKGMAKIRIKSKINYEEDVYLGFIENMSENVLVTYKE
                     LNIENSDTILDIKVKYDFSYKLKDVLDEIKASFPNSIDIEVISNFNPVYFDKESNLVK
                     KLQLAYERVTSLDGTPVTTNGGTYAKVMPNIVPFGPSFPGQKGIAHNPDEYMDIEDII
                     LNAKIFANAIYELAKE"
     gene            33979..34653
                     /locus_tag="PC465_001579"
     CDS             33979..34653
                     /locus_tag="PC465_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HDF2648896.1"
                     /translation="MLEIIGMSVEDAKIIEDCGADRIELVSALTEGGLTPSFGLIESV
                     VNSVKIPVNVMIRHHAKSFVYSKEDISIMQKDISVVKEIGANGVVFGVLDKNNSIDEK
                     NLNVLLKCCDNLDVTFHRAIDESNTIDSVKILKDYDKITNILTSGGKGSIVDNIQMIK
                     NMMLSSNHIKILLGGGLNFNNIEKIKELTKASNFHFGTAIRINNSPFEDIDRQKLKQL
                     VNIISR"
     gene            35206..35757
                     /gene="raiA"
                     /locus_tag="PC465_001580"
     CDS             35206..35757
                     /gene="raiA"
                     /locus_tag="PC465_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDF2648897.1"
                     /translation="MNIIISGKQIELTDAIKNKIETKLSKLDNYIHPDTDVKVTVSAR
                     KARQKIEVTIATVNGPIIRAEDMQENLYTAIDVVYDKLSKQLKKYKKRLQDKHKDNKS
                     IRFQDAEINLADEQEDYGDENQELVIQRRKKFSVKPMSEEEAVLQMELIGHDFYMFKN
                     IDSDEIAVVYKRNNGGYGIIEHE"
     gene            35889..38564
                     /gene="secA"
                     /locus_tag="PC465_001581"
     CDS             35889..38564
                     /gene="secA"
                     /locus_tag="PC465_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDF2648898.1"
                     /translation="MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNM
                     TNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKT
                     GEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
                     PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEAR
                     TPLIISGPGDKSTHLYSDANTFVLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDN
                     ITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQ
                     AIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVP
                     TNKLMIREDLPDCVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKK
                     KGIKHEVLNAKHHDKEAEIIAQAGRLGAVTIATNMAGRGTDIVLGGNPDFLTKREMRR
                     NGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVEAGGLA
                     IIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLE
                     EDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGED
                     LQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLFLPKGSIEIPEIEKLNPVEI
                     TEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRA
                     VGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSD
                     GTLPTSKTVKKDEKVGRNDLCPCGSGKKYKNCCGR"
     gene            38579..39686
                     /gene="prfB"
                     /locus_tag="PC465_001582"
     CDS             join(38579..38653,38655..39686)
                     /gene="prfB"
                     /locus_tag="PC465_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153309863.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HDF2648899.1"
                     /translation="MLKLQEYRHSMEQMASNLEELRVSLDIASLMKNIQINEEKMNQQ
                     DFWNDNEVAQRVLQENKSLKETLEEYESLKSLLEDIEVLIEIGLEEDDDSVERDIEKS
                     IESMEEKLSEMKIKTLLNGEYDKNNAILSINAGTGGLDAQDWAQMLLRMYIRWSESKG
                     YKVKLLDIISDPEAGIKTATILVEGTNAYGYLKSEKGVHRLVRISPFDPSGKRHTSFA
                     SIDVTPELDENIEVEINPSDLKIDTYRASGAGGQHVNTTDSAVRITHIPTGVVVQCQN
                     ERSQHLNKDRAMRLLMAKLIELKELEQKEKIEDIQGKYSQITWGSQIRSYVFQPYKLV
                     KDHRTNAEFGNVDSVMNGNIDLFINEYLKMNKIV"
     gene            39830..41971
                     /locus_tag="PC465_001583"
     CDS             39830..41971
                     /locus_tag="PC465_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HDF2648900.1"
                     /translation="MDINQILKKEFNLRDEQINNTLKLIDEGNTIPFIARYRKEMTGE
                     MSDVTLREFYEKLMYLRNLQSRKDDVVRLIDEQGKLTDEITQNIEKAKTLQEVEDIYA
                     PYKQKKRTRATIAKEKGLENLALSILENNLDNIEIESKNYLDEEKEVLSIEDALKGAR
                     DIIAELVSDDAKIRKYIRELALREGMIVSKSATDEKSVYDMYYDYSEAVKSMAPHRVL
                     AINRGEKESFLKVKLEINNDKVLNYIINEYVNDKNFKNKEEIVSSIEDSYKRLIFPSI
                     EREIRNHLTEIAQERAISVFGKNVKSLLLQPPVKDKVVMGFDPAFRTGCKIAVVDKNG
                     KLLDYTTVYPTDPQNDVEGAKKVLKGLIEKYDIDIISIGNGTASRESETFVSEMIKEI
                     DSEVQYVIVSEAGASVYSASELANEEHPDINVSIRGAISIARRLQDPLAELVKIDPKS
                     IGVGQYQHDLNKKRLEEVLDGVVEDSVNSVGVDLNTASYSLLEHVAGISKAIAKNIIA
                     YREENGDFTSRAQLKKVKRLGPQAFTQCAGFMRILEGKNPLDNTGVHPESYDICKKMI
                     EIIGYSLDDVKNKNIGEIDEKIKEIGLRELSEKLEVGQVTLKDIIAEIKKPGRDPREE
                     GIKPILRTDVLKIEDIQEGMTLKGTIRNVVDFGAFVDIGIKNDGLVHKSEMSNSFVKD
                     PMSIVTVGDIVDVKVIGIDLNKKRVALSMKK"
     gene            42119..43285
                     /locus_tag="PC465_001584"
     CDS             42119..43285
                     /locus_tag="PC465_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2648901.1"
                     /translation="MIFIKNGKINTITNGIIHGDILIDEGKIIEIGEDLIAPLDVEVI
                     DASNKLVFPGFIDAHTHLGLWEDGIGFEGADGNEETDPITPQLNPIDGINPMDRTFKE
                     AFEGGITSVCTTPGSANVMGGQCIAIKTCGKRIDKMVIKNPVASKIAFGENPKSCYGQ
                     DDKSPQTRMAIAALLRENLKKAEEYLEDIDMYESHDDEDCEKPEYDIKMESLIPVLRR
                     EIPFKAHAHRADDMFTAIRIAKEFNLKLTLDHCTEGHLIVDELVEEGFPVIVGPSLSE
                     RSKFELRNLTFNTAGILSNAGLDVCIMTDHPVIPVQYLPICAGIAVKHGMKEEKAIES
                     ITINPAKTLGIEDRVGSIEVGKDADLVIWDNSPLEIQSNVLYTIINGKVVYEKK"
     regulatory      43345..43462
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            43587..44192
                     /locus_tag="PC465_001585"
     CDS             43587..44192
                     /locus_tag="PC465_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2648902.1"
                     /translation="MQNTAKRGNMISTRTLVVMSILSAISYLLMFIQAPIPGIFPDFL
                     KIDLSDIPAIFGGMSLGPLVGFGIVVVKNVLQAITATTTGGIGEFANILIGGSYVMIL
                     CYSYKRSGDLKGVLIGFVLGTISMTIIGSLVNYFVMLPLYGQLMGLDAIIGLGSAINP
                     QVHDLFTFVIWMIAPFNVLKAVIISLVTLPLYKKMGNIIKK"
     gene            44521..45561
                     /locus_tag="PC465_001586"
     CDS             44521..45561
                     /locus_tag="PC465_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HDF2648903.1"
                     /translation="MHLSKKIKKLFLDDKGYYFNSNWKDIHIGIYDTKLGDSLKYITN
                     EYIENMERVKYDYRELKNIENQTDGMCILAIRQNYKALEYVKNQTEELCLEAIKYNYK
                     ALEYVKEQTEYLCLEAIKKDCNALKYVRNKTEGLIIKAISHSSNIDVVSILKALETQT
                     RRICLEAIKKDGRCLAYVREQSEELCIEAIKQNYKALKYVKNQTEKMCIESVRQNGMA
                     LQYVNKQTDKICIEAVKQDGRSIQFVNNKTEEICINAIRYLNKKYNIKDVLSYIDKYT
                     EDICIEIVRQNGKMLMYIKNQTEKMCIEAVKENYKSLKYVKEQSERICKEALKQNHKA
                     KEYVKIAIDDCI"
     gene            45700..46152
                     /gene="tsaE"
                     /locus_tag="PC465_001587"
     CDS             45700..46152
                     /gene="tsaE"
                     /locus_tag="PC465_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HDF2648904.1"
                     /translation="MAKIYLENENKTREIGYKLGKLLKEGSVICLVGDLGAGKTTMTQ
                     SLADSLGIEDYITSPTFTIINEYEGKIPLYHFDVYRIGSSDEMYDIGYDEYVNSNGIC
                     IIEWANLIEDILPKEYLNIELRYKDEGREMILTPKGEFYKEIVEELIK"
     gene            46152..46868
                     /gene="tsaB"
                     /locus_tag="PC465_001588"
     CDS             46152..46868
                     /gene="tsaB"
                     /locus_tag="PC465_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HDF2648905.1"
                     /translation="MKILGMDTSSMAASVAVVEDDNLICEFTVNNKKTHSQKLMPMIE
                     NMLSMSDLSIKDMDLLAVCIGPGSFTGLRIGMATVKAMAHVNNIPIIAVNSLESLANN
                     INFCDRKICCILDAQKNQVYSAKYKFENGEMIELDGVDVVDFDALVDEIVSTNEEFII
                     VGEAVYKYKDKLENIKNIKIPSPANNVSNAGSLCSLALNKYNKNIDVHTCYTINPMYI
                     RKSQAEVQYDEKMKRLNNGR"
     gene            46858..47334
                     /gene="rimI"
                     /locus_tag="PC465_001589"
     CDS             46858..47334
                     /gene="rimI"
                     /locus_tag="PC465_001589"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HDF2648906.1"
                     /translation="MEDNTKLIVDDIKIEEMTTEDIDEVFEVEKNCFEDYWSKESFRK
                     ELSNEVARYIVAKLNGKIVGYVGIWLILDEGHINNVAVHSDYRGKKIGDKLIKGIVDL
                     CKDNNIASMTLEVRASNKIAQNLYRKYGFKMGGIRKEYYSDNKEDAIIMWNQLKEV"
     gene            47340..48356
                     /gene="tsaD"
                     /locus_tag="PC465_001590"
     CDS             47340..48356
                     /gene="tsaD"
                     /locus_tag="PC465_001590"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HDF2648907.1"
                     /translation="MSDIITLAIESSCDETAASVLKNGREILSNIISTQIETHKKFGG
                     VVPEVASRKHVENIDIVVQEALDKANIGFNDIDHIAVTYGPGLVGALLVGLSYAKALA
                     YTLNIPLVGVNHIEGHLSANYIEHKDLKPPFITLIVSGGHTHLVEVKDYGKYEILGKT
                     RDDASGEAFDKISRAMNLGYPGGPIIDNLAKNGNKHAIEFPRAYLEEDSYDFSFSGLK
                     SSVLNYLNGKRMKNEEIVVEDVAASFQEAVVEVLSTKALKAVKDKGYNIITLSGGVAS
                     NSGLRAKITELAKDNGITVKYPPLILCTDNAAMIGCAGYYNFINGKTHDMSLNAVPNL
                     KINQ"
     gene            48653..51361
                     /gene="hpdB"
                     /locus_tag="PC465_001591"
     CDS             48653..51361
                     /gene="hpdB"
                     /locus_tag="PC465_001591"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase large
                     subunit"
                     /protein_id="HDF2648908.1"
                     /translation="MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLL
                     DVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKAAFSHMTPNIIPGEKIVMQ
                     KTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
                     VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFD
                     SGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVI
                     QVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAHKQPRTFREALQLT
                     YTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCID
                     CFASAGVNGGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLY
                     DEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCL
                     ETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDYRMNIQVFE
                     PHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKG
                     QHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEIKDAILNNFGFKD
                     ALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEE
                     AQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYSDGSVSAYAGTDKNGVYAL
                     FESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSE
                     TLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV"
     gene            51365..51622
                     /gene="hpdC"
                     /locus_tag="PC465_001592"
     CDS             51365..51622
                     /gene="hpdC"
                     /locus_tag="PC465_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase small
                     subunit"
                     /protein_id="HDF2648909.1"
                     /translation="MRKHSDCMNFCAVDATKGICRLSKQMINLDDAACPEIKVMPKCK
                     NCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE"
     gene            51615..52565
                     /gene="hpdA"
                     /locus_tag="PC465_001593"
     CDS             51615..52565
                     /gene="hpdA"
                     /locus_tag="PC465_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase activase"
                     /protein_id="HDF2648910.1"
                     /translation="MSSQKQLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANP
                     ESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECV
                     NSCYYNAFKLCAKPYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKC
                     HEVNVHTAIETSACVSNEVFNKIFNDIDFAFIDIKHMDREKHKEQTGVYNDLILENIS
                     NLANSDWNGRLVLRVPVISGFNDSDENISDIISFMHKNNLVEINLLPFHRLGESKWTQ
                     LGKEYEYSDKGDVDEGHLEELQDIFLDNGIACYVGHETAF"
     gene            52880..53842
                     /locus_tag="PC465_001594"
     CDS             52880..53842
                     /locus_tag="PC465_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2648911.1"
                     /translation="MNKSWSNLIIKNKDRKVRSGWIIIAVMATFYILQYYLSMILVEI
                     IRKILVATGDINLKTNYFSEYANWLNDVGLQIVFQILTDSLMIIIPIIVWRFIMKNPI
                     SEMGLHSYRIKKKEGYVGMLLGIFNCTVIFIITITIGGGHVTSWVPKISPLTVSWILV
                     FILVAFAEEILNRGFFMAVLRRCKNIYFIMIVPSVIFGLIHIWNPDVTFLSVINIIII
                     GILFSYMFIKSSNIWMCIGYHFTWNVFQGIIYGMPVSGLQVPGIITTQITHGNLLNGG
                     MFGIEGGILTTFVNLLSFIFVWYYYRDSKYDFVSDKVNVTNIKN"
     gene            complement(53941..54921)
                     /locus_tag="PC465_001595"
     CDS             complement(53941..54921)
                     /locus_tag="PC465_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2648912.1"
                     /translation="MNLKLIWINILNPVFIKNEIKRKKIQIIIFFFINFDLTYSLGLL
                     LYYNKFIDPENFASFMMILPLSSVAIAKFYTEGLNNDMYEFYSLIILFFLIYSLLIVL
                     KLLNLINNNEFIIINLILIFISSLSIIIYSSNKKNLYPVKNIKLGSLLIIYFMISVIV
                     PTSFILILQGAQPNYSGIIKFIFTPITSLTTIYIFFSEEYAWRGFLQNIFFDKFGKKL
                     GVIILGMCWSLWHLPLIFTLYTPEAPILGIILRSIHIVGISIFLGYLYIKTKNIWFCA
                     IIHVLNNSAFLITNSKESTITYHDILIVSMVVLIFYVPFLFTKEYKNNLE"
BASE COUNT        22156 a         5818 c        10377 g        16630 t
ORIGIN      
        1 tttaggtatt gtgtattatt ttcactgtag gagattatat ctagttatac ataataagtt
       61 ttaatgatag tttatagtaa gatattaaaa taaatttatc taatctagat atgaaataag
      121 ttattacttt aatataaaaa tgaatctaat ggaataatat tgatgataag taatatttag
      181 attttgtatt tgtttatagt taataagtgg attatagaat ttataataat taatatatat
      241 taaacaaaga tatattaaga tattttagaa cacaaaactg cattaaggcg cgagtactat
      301 tttgtattcg cgccttgatg gtttgagtta tttgagtaaa aactaacttt aataagaaat
      361 ctgtatttat taagttgata tttttaatgt gtttagagat tatttaacaa tctccaaata
      421 taaaactaga attatttaca taaaagttaa atagtttgta tagagttaga tttatatagt
      481 ataatactta gtgtaaataa ttaagaagtt atcaaacagg aggataaaac tgtgttagat
      541 ataaattctt ttttaaatgg attttttaat ataatattaa gaatgagtat atatgattta
      601 attgacatat ctatagtagc gtatattttt tacaaaatat ttatgtttat aaaagataca
      661 agagcagaac aagtgtttaa aggtataata tttcttttat tagcaactca acttagtaac
      721 acctttaaat tgcataccgt ttattggata tctcttaaag ctttagatta tggagttata
      781 gctgctctta taatttttca accagaattt agagcaggac ttgaacatat aggaagagca
      841 aagtttaatt tatttggaaa gaatgtaaat acttctgaag aaactctcaa tagaaatata
      901 gaagaaattg tagaagcttt atattcactt tctagacaaa aaataggagc tcttatcata
      961 atggagagag aaactagaat aagtgatata ataaatacag gaactattat tgatgctgaa
     1021 atttctaggc aactattaat aaatatattt ataccaaata caccattaca cgatggagct
     1081 gttgtaatta gagattctaa ggtaaaagca gctgcatgtt ttttgccatt gacagaaagt
     1141 aaggatttaa gtaaagattt gggtactaga catagagcag gaataggggt aagtgaggtg
     1201 tctgactgta taactttgat tgtatcagag gaaacaggtg gcgtatcaat tgctaaagca
     1261 ggtaagttat atagagatat ttctagagaa agaatgatga atatattacg tagtaattta
     1321 aaaacaaata cagaaacaag aagttttttc aaaggtggta tatttaaatg ataaatagac
     1381 taaaaaataa taccaaaata aaaataatat catttttaag tgcaattgca ttatggatgt
     1441 atgttatggc tgtagttgac cctgaagaaa ctaaagggtt tgaagatata cctgtatcta
     1501 taagtaatat gagtgattta aaggataaaa atcttgttat atatccagac gaaaaattaa
     1561 cagcagatgt atatataaaa ggtagtttat caaaggtaca aagtgttaaa aaagaagata
     1621 tacatgtata tggaaccatt gaagacccaa tacaaggaca gaaggaagta tatttaaaag
     1681 caaatattcc tcaaggtgtt actctagaat ttaagcatga tgttttagta gtaaatcttg
     1741 aaaaaaacat aaaagaaaaa agagatataa aggtagaagt aagtggaaat tcaaaaagaa
     1801 atataaataa aattgaactt agtaaggaat ttgtcgatgt atcaggtcca agaactctag
     1861 ttaaagaagt caaaagtgta agagctaatc tagatgttgg taatgagaca gatgattttt
     1921 ctaaaaaatt gcaattaata ccattaaata gtgatggaac taaggttgaa ggagtaacat
     1981 taagttcatc ctttgtgact gcaaagatag aactattgaa ggaaaaaatt gtcccaataa
     2041 gagtaagtct aaatgataat aaagataatg atgtactgaa aaactataaa ttaagtaagg
     2101 aacaagttac aataaaagga aagaaagaag atatagacaa aataagttat attaagacaa
     2161 aacctattga cttagctgat ttggctaatg gtgaagaaaa agaagttagc ttagaaattc
     2221 cagagggtat aactcttgag gatagctcta taacaattaa attaaatgat acaaaacaat
     2281 tgagtgcaga atttttatat aatgcgggag atattgaatt aagaaatatc ccaacaaata
     2341 tggataatcc aaatgtaatt tctgatgtag atataaaagt tgttgtagag tcaacggagg
     2401 atttgagtaa gttaaataaa aaagatattt cattatatat tgatttatca caaggccctg
     2461 aggaagatag taaatataaa ataaaatatg aaacaacata tcaatttaaa aaaataaata
     2521 tagaacctaa tattgttgaa gtggaatgaa caaatatttc gaatatttag ttgttacaag
     2581 atgcgacaaa aaaacctata aaattaagtt tgttaatttt atgtttttgt tgcatcttgt
     2641 ttattttagt tatattataa aataaggaca atgagatatt tgttaaatct aaaaagcgct
     2701 agatatatga aaaaagactg ataaatagat ttaaataaat attttgaatt aaatatttca
     2761 attatctcta ggaaaacgtt gctgaacgag ttataattta attgagatat aaaaagttct
     2821 atttcaaaaa attcaagatg aggtggaaat gcatgagaag ttttgaagaa gtaattaagt
     2881 ttgcaaaaga aagaggacct aaaactatat cagtagcatg ttgccaagat aaagaagttt
     2941 taatggcagt tgaaatggct agaaaagaaa aaatagcaaa tgccatttta gtaggagata
     3001 tagaaaagac taaagaaatt gcaaaaagca tagacatgga tatcgaaaat tatgaactga
     3061 tagatataaa agatttagca gaagcatctc taaaatctgt tgaattagtt tcacaaggaa
     3121 aagccgacat ggtaatgaaa ggcttagtag acacatcaat aatactaaaa gcagttttaa
     3181 ataaagaagt aggtcttaga actggaaatg tattaagtca cgtagcagta tttgatgtag
     3241 agggatatga tagattattt ttcgtaactg acgcagctat gaacttagct cctgatacaa
     3301 atactaaaaa gcaaatcata gaaaatgctt gcacagtagc acattcatta gatataagtg
     3361 aaccaaaagt tgctgcaata tgcgcaaaag aaaaagtaaa tccaaaaatg aaagatacag
     3421 ttgaagctaa agaactagaa gaaatgtatg aaagaggaga aatcaaaggt tgtatggttg
     3481 gtggaccttt tgcaattgat aatgcagtat ctttagaagc agctaaacat aaaggtataa
     3541 atcatcctgt agcaggaaga gctgatatat tattagcccc agatattgaa ggtggtaaca
     3601 tattatataa agctttggta ttcttctcaa aatcaaaaaa tgcaggagtt atagttgggg
     3661 ctaaagcacc aataatatta acttctagag cagacagtga agaaactaaa ctaaactcaa
     3721 tagctttagg tgttttaatg gcagcaaagg cataatttta agggggaaat aggcaaatga
     3781 gcaaaatatt taaaatctta acaataaatc ctggttcgac atcaactaaa atagctgtat
     3841 ttgataatga ggatttagta tttgaaaaaa ctttaagaca ttcttcagaa gaaataggaa
     3901 aatatgagaa ggtgtctgac caatttgaat ttcgtaaaca agtaatagaa gaagctctaa
     3961 aagaaggtgg agtaaaaaca tctgaattag atgctgtagt aggtagagga ggacttctta
     4021 aacctataaa aggtggtact tattcagtaa gtgctgctat gattgaagat ttaaaagtgg
     4081 gagttttagg agaacacgct tcaaacctag gtggaataat agcaaaacaa ataggtgaag
     4141 aagtaaatgt tccttcatac atagtagacc ctgttgttgt agatgaatta gaagatgttg
     4201 ctagaatttc tggtatgcct gaaataagta gagcaagtgt agtacatgct ttaaatcaaa
     4261 aggcaatagc aagaagatat gctagagaaa taaacaagaa atatgaagat ataaatctta
     4321 tagttgcaca catgggtgga ggagtttctg ttggagctca taaaaatggt aaaatagtag
     4381 atgttgcaaa cgcattagat ggagaaggac ctttctctcc agaaagaagt ggtggactac
     4441 cagtaggtgc attagtaaaa atgtgcttta gtggaaaata tactcaagat gaaattaaaa
     4501 agaaaataaa aggtaatggc ggactagttg catacttaaa cactaatgat gctagagaag
     4561 ttgaagaaag aattgaagct ggtgatgaaa aagctaaatt agtatatgaa gctatggcat
     4621 atcaaatctc taaagaaata ggagctagtg ctgcagttct taagggagat gtaaaagcaa
     4681 tattattaac tggtggaatc gcatattcaa aaatgtttac agaaatgatt gcagatagag
     4741 ttaaatttat agcagatgta aaagtttatc caggtgaaga tgaaatgatt gcattagctc
     4801 aaggtggact tagagtttta actggtgaag aagaggctca agtttatgat aactaatgat
     4861 aaaagaataa gaatcataac tggtcactat ggaagtggta aaagtgaatt tgcgatgaac
     4921 tatgttgtta agttaagaga tatggtttct ggcaaagttg ctatagccga tttagatgtg
     4981 gtaaatgtat actttagaac tagagaaaag aaagagttaa tgaaatcctt aggtatacaa
     5041 ccaatagata gctcaattaa tgctccaaca ttagatttac cagcagtatc agcagaggta
     5101 atgtctccta tggtagacca ttcatacaat tctgttatag atttaggtgg agataatgta
     5161 ggtgctaggg ttataggaag atttagtcat ttgttaaaag aaggcgatta tgatatgctt
     5221 tttgtaataa atgcaaatag ggagaaaact caaacttctg aagaagttat ccaatatata
     5281 aaagaaatag aaaaatcttc taaattaaag gtaacaggtc taattaataa tactcatctt
     5341 attaggttta ctactattga tgatgtttta agaggtcaga aagttgcaaa agaagtttct
     5401 gaaaaatgta atataccgat aagatatgtt gcatgtttag aaaatcttgt tgaacagtta
     5461 ccaaaagatt tagaaggaga aatttttcct ataaaattat atatgagaga agactggatg
     5521 tagtttgagc tcaaatatat agaaagttta aggaggctta ggtaaatggc taaaggaaaa
     5581 gtatctttta atcaagaacg ttgtaaaggt tgtggattgt gtgttgaagc atgtccagta
     5641 aaaatcatac aattagactc aaatgtaata aacaaaaaag ggtataaccc agcaactgtt
     5701 tttgaaatgg aaaaatgcat aggatgtgca agttgtgcaa ctatgtgtcc agatgtagtt
     5761 ataacagtag aaagagatta atttaattaa tatttaaggg ggaattttaa tggctaagat
     5821 acttatgaaa ggtaacgaag catttggaaa agcagctata gaagctggtt gcaaatattt
     5881 cttcggttac ccaataactc cacaaagtga attaccagaa tatttatcaa gagagttacc
     5941 taaaataggt ggagcgttcg ttcaagctga atcagaagtt tctgcgataa acatggttta
     6001 tggtggagca ggtgcaggag caagagttat gacttcttca tcttcaccag gagttgcttt
     6061 aaagcaagaa ggtataacat atgcagtagg agcagaagtt ccttgtgttg tacttaatgt
     6121 aatgagaggt ggtccaggac ttggaagtat acaaccttca caagctgact actttatgtc
     6181 tacaagaggt ggaggaaatg gagactacag aactccagta ttcgcaccag ctacagttca
     6241 agaagctgtt gatatgataa tggaagcttt tgacgttgca gattattaca gatcaccagt
     6301 tatggtagtt gcagatggta tgataggtca aatgatggag ccagttgaat ttagagctcc
     6361 tgagaagaaa agagaattgc ctcctaaaga ttgggcaact gttggaacta aaggaaaaag
     6421 aaaacctaat gtaataaact ctctatactt agagccagaa gtactagaag accattgttg
     6481 gcatttacaa gaaaaatttg atgcaatgga aaagaatgaa gtacaatacg aaatgtacaa
     6541 aacagaagat gctgaatttg tatttgcagc ttatggaact acttcaagag tagtaaaaag
     6601 cgcaattgat atattaagag aagaaggaat aaaagcaggt cttataagac ctaaagtatt
     6661 atggccattc ccattcgaag cattcaacca aattcctaat gctagaaaca tattgactgt
     6721 tgaaatgagt atgggacaaa tggtggaaga tgttaaaatg gcagtagaag gtaaattacc
     6781 agtttacttc catggaagac caggaggaat gactccaaca ccagcagaaa tagttgaaaa
     6841 agctaaaaaa attattgccg gagaattggt tgcaggaggt gctagataat ggctgttgta
     6901 tttaagaaaa ctgaaggatt acaagatact caaactcact actgtccagg atgtacacat
     6961 ggtataatcc atagattagt tggtgaagta ttagaagaac taggagtatt aggtgatgct
     7021 gtaggtgttg ttccagttgg atgttcagtt ttaggatata aatattttaa ctgtgacact
     7081 caagaagctg ctcatggtag agcgccagct gctgctacag gaataaaaag agttcatcct
     7141 gaaaatacag tattcactta tcaaggtgat ggagacttag cttcaattgg tactgctgaa
     7201 atagttcatg cagctgctag aggagaaaaa ataactacta tatttgtaaa caatacaact
     7261 tatggtatga ctggtggaca aatggctcca actacattag ttggacaaag agctactact
     7321 gctcaatcag gaagaaatgc tgaaactcaa ggttatccaa taagagtaag tgaaatgtta
     7381 gctacattaa caggagctgt atttgtagaa agagtagcag ttgatactcc agctcatgtt
     7441 agacaagcta aaaaagctat aaagaaagca ttccaagttc aacaagcagg attaggattt
     7501 ggaatagtag aagtattatc tacttgtcct acaaactggg gactagctcc aaacgatgct
     7561 ttacaatggt taagagacaa catgatacca tactatccat taggaaattt caaaaatgtt
     7621 gaagttgagg aggtgaagta aatgtctaca gctagagtaa tatgtgcagg cttcggaggc
     7681 caaggtgtta tgtctatggg acaattactt acttatgcag gaatgctaga aggaaaagaa
     7741 gtttcttggt taccatctta tggaccagaa atgcgtggag gtacagcaaa ctgtgcagta
     7801 actgtatcta atgagccagt tggttctcca cttataacag atgatgcaac tgcagctata
     7861 ttattaaata taccagcatt tgaaaaattc aaagatgatg ttattcctgg tggaaaaata
     7921 atagtaaata gttctttaat aaaagaaaaa gttgatagaa cagatgtaga tgtttattat
     7981 ataccagcaa atgaattagc agctgaatta ggaaatgata aagttgctaa catgataatg
     8041 ttaggcgctt acttaaaagt atctgatact gtagatatag aatctgtact agaagcattc
     8101 aaaaaagttt tcggacctag aaaagaaaaa ttcgttccat taaacagaga agctttacaa
     8161 aaaggtatgg atgctacatg ttctaaagca actaactaat aaagaaaaag atgtcaaaaa
     8221 aaagacaata gaattatttc tattgtcttt tttgctgata agtattaaaa tatttttatg
     8281 actgaaatta agcctataat gatattttat gaactataaa aatataatac aaattacaag
     8341 cttttcaatt atgaaaggag aatctttagt gagaaagtat tttggaacag atggagttag
     8401 aggagtagca aatacagaac taacatgtga tttagcatat aaacttggta gagctggtgg
     8461 atttgtctta gctcaaggag accacagagt aaaagtagta gtaggtaagg atactagaat
     8521 atcaggtgat atgttggaag catctttaat agcaggactt atgtctgttg gatgtgatgt
     8581 tattactgtt ggaataatac caacacctgc agtggcatat ttaactagaa aatatggtgc
     8641 tgattgtggt gtggttatat ctgcatctca caatcctgtt gaatataatg gaatcaaatt
     8701 ctttaataag aatggatata aattagatga tgaaattgaa ttgaaaatag aagaatatat
     8761 agacgatata gacaaaattg attgtcttcc aattggtgaa aatgtaggaa gaaaattaca
     8821 tgaacattgt gcacaaagag actatgtaga ctacctaaaa tcaataataa gcactgactt
     8881 taagggatta aaagtagttt tggactgtgc taatggtgcg tcatataaag tggcaccaat
     8941 agtgtttgat gaactaggag caagtgtaat ttcaataaat agtttaccag atggaaataa
     9001 tataaactat aaatgtggct ctacacatcc agaacaactt caaagggctg ttttggaaca
     9061 taatgctgac ttaggtcttg catatgatgg agatgctgat agattaattg cagtaaatga
     9121 aaagggtcaa attgttgatg gagaccatat aatgatattg agtgccttaa atttaaagaa
     9181 aaataataaa ttggcacaag atactttggt agttacagtt atgagtaata tagggttgac
     9241 aatagctgct aaggaaaatg gaataaattt atctactaca gcagttggag acagatatgt
     9301 tttagaagat atggttaaaa atggatataa tcttggtgga gagcaatctg gacatatgat
     9361 atttttagat tacaacacta ctggagatgg agtgcttagt tctctaatac ttgcaaatat
     9421 aattttgcaa gaaaagaaac ctttatcaga aattgcatca ataatgagcc aatacccaca
     9481 agtattagta aatgcaacaa taaaaaatga aaataagaac aaatatatgg aatatccaga
     9541 aataaaaact gagatagaaa gaatagaatc tattttagac ggaaatggta gagttttgat
     9601 aagaccatca ggaactgagc cattagttag agttatgtta gagggtaaag aggaaggtca
     9661 aataaaagaa ttagcaacag acttagctaa tcttatacaa gaaaaattat cgtaatttaa
     9721 agggtattct cagatacaaa tactgaggac acctttctaa gcgccagaac ttagttatag
     9781 acataattat tgagtaatat aggaactaag ttgacgaggt cagagttaat cgaattgtcg
     9841 gcggatgctc tgcggtgtgt ttaccatcga aagacttctt taaataatag gagcaatcct
     9901 atggacaaag ggaagccaaa gtaaacttat atgacctaac tcttaaaata tataaataat
     9961 atttttagga ggacacaaat aatgtgtgga atagttggat atttaggaag tagaaaggca
    10021 gcagaagtta tagtagaagg gctttctaag ctagagtaca gaggttatga ctcagcagga
    10081 gtagcagtta atagttctaa tgaaaaagaa cttaatatta gaaagtttaa aggtagactt
    10141 tctgtacttg cagaagactt agaaaagaat cctattgatg gaaatttagg tatagggcat
    10201 acgagatggg caactcatgg agaaccatct gatgtaaact cacatcctca ttttaatcaa
    10261 gccaaaacaa tagcagttgt tcataatggg ataatagaaa actatatgga aataaaagaa
    10321 gaattaattt ctgaaggtgt taagtttgaa tctcaaacag atacagaggt aatagcacat
    10381 ttagtagata aatactatga gggtaattta ttagatgctg tatacaaaac tatatcaaaa
    10441 ttaagaggag cttatgcatt aggtgttata tgtaaagaac atggaaatga attagttgca
    10501 gtaagaaaag atagtcctct tgtagttggt gttggtgaag gtgaaaactt tatagcatca
    10561 gatatacctg cattattaaa atatactaga gatgtttatt tcttagaaaa tggagaagta
    10621 gttcatctaa aagacgaaaa tgtaaccgtt tatgactcta atagaaatct tgttgaaaaa
    10681 gaagtatttc atgtaacttg ggatgtagaa gctgcgtcta aaggtggata tgactacttt
    10741 atgtcaaaag aaattcatga gcaaccaaca ggagttagag aaactttaga aagaagactt
    10801 gatgataatg gaaatataat tctagacagt ataaatattt ctaaagaaga cttagaaaaa
    10861 ataaataaag tttatatagt ggcttgtgga acagcatata atgctggatt acttggtaag
    10921 tatgccatag aaaaatttgt aaatatacca gtaataactg atatagcatc agaatttaga
    10981 tatagcgacc catttgtaga tgaaaattca ttagtaatat tagttagtca atctggtgag
    11041 acagcagata ctctagcagt attaagagat tcaaaggcta aaggagcaag aatactttca
    11101 ataactaacg ttgtaggttc atctatagca agagaatcag atgatgtatt ctatacttgg
    11161 gcaggacctg aagtagcagt tgcatcaact aaggcatata ctactcaaat aacttcttta
    11221 tacatgatag ctttagactt tgctatcaaa aaaggaacaa taactagaga attttatgat
    11281 agtatgattt ctaagatgaa agaaatacca tcaaaaatac aagaaatact agacaatgaa
    11341 gaatatataa aagaagttgc taaaacagtt gttagttctg aacatgcatt ctatttagga
    11401 agaggtatag actatagctt agcaatggaa ggttcattga aattaaaaga gatttcatat
    11461 atacatgcag aagcttttgc agcaggagag ctaaagcatg gaacaatagc tttaatagaa
    11521 aaaggaactc ctgtaattgc catagctact caagaaaagt tatttgaaaa aatggtttct
    11581 aatatggaag aagtaagagc aagaggagct tatgtagtag caatagctca aagccataat
    11641 aaggatgttg agaaagctgc tgataaaata atctatatac caaattcaga tgatatttta
    11701 tcaccaatat tagcagttgt accaatgcaa ttacttgctt atcatgtctc tgtactaaga
    11761 ggatgcgatg tagataagcc aagaaatcta gctaaatcag taacagttga ataaaaacag
    11821 attaaaaatt aaatagataa tatttattga aaagaactca tcctgttatt tgtattttat
    11881 aggatgagtt ttttagataa atattaaatt tgttttgttt ttgctataat aaattttata
    11941 aaaagattga tattaaatca tctgtaaaat gataaatata tagaccatac caggtatagg
    12001 gaacgataaa tatagttcat ataaaatata gtgagtactt aataaacata tagtcaatat
    12061 cagataaaaa aaataatagc ttatgagaaa aattaaaata caaggtatta gtaaccttgt
    12121 gataagataa agtgagtagt ttaaaataag aatataagga actatttata aaagaatata
    12181 atgaagctaa tagagtataa gaaaattact ttattttagt aaaataattt caaataaaaa
    12241 tttttttaaa ttgggagtat aaattatgac aaatgatttt aaaaaagaaa agaaagaaga
    12301 ttattttgtt aatcttaagg caatatctac tgaagtttta caagaaaaag tgcaagataa
    12361 cgcttgggtt atagttgata ctcgcttaaa tgatgcttat aatggctgga agttagatgg
    12421 agtaagaaga ggtggacata taaaaggagc agtagatttt tctgctaatt ggttaagtgt
    12481 atacttagat agaaaagatg aagtgttaga acaagcattg aaaactaaaa gaattgattt
    12541 agataaaaat atagtattgt atgatgcaaa tggaaaagat gctttggttg tagcagatta
    12601 tttatctaaa aaaggatata aatatctata taaatatgat attaaacaat gggcagacga
    12661 cgaaaatctt ccaatggaaa gatataaaaa ttatcaaatg atagttcctg cttttataat
    12721 aaaagatata ttagatggaa aaattcctga gacatttgaa gattcaaaga atataaaaat
    12781 gattgaagcg agttggggag aagaatcgta tacaaaaggg catataccta caagtgttca
    12841 tgtaaatact gatattatag aacctcctcc aacatggatg cttgataatg atgataactt
    12901 aactaagttt gctttagact atggattaac aaaggatgat actgtaatag tttcaagtag
    12961 tacacctatg gcatcttata gactagctgt tatattgaga tatataggag taaaagatgt
    13021 aagagttttg aatggtggaa caaactcatg gttatcagca ggatatgaat tagaatttat
    13081 tagtaatcca aaacattcat gtactaattt tggagcagat ataccagtta actcacaatt
    13141 agttgttact acatctgaat taagacaaaa actaaaagaa aaaaataagt ttatactagt
    13201 agataaccgt acttgggatg aacatatagg aaaagtatct ggatatacat attatgataa
    13261 aaaagggcgt ataccaggag ctttatatgg acattcaggt agtgatagtg tttcactaga
    13321 agaatatcgt aatattgata atacaatgag aaataaatat gagattttag aaatgtggga
    13381 caaggaaaat atagatgtga ataaacagct tatatttatg tgtggaagtg gatggcgtgc
    13441 tgctgaagta ttaacatatg caaatgtcat aggagtggaa aatacctccc tttatagtga
    13501 tggatggatg ggctggagtc ttgataattc aaatttaatt gaagtgggag aacacaaata
    13561 aagtttttga aagtacaata gagttgttta aaacaaaggt gtttttgatt tattaggaag
    13621 agtgtgtaaa ttgtgtattg ggaagtgtac ttaggtatgt tcatttggag ctatggaaat
    13681 tgataaaaaa gtattatctg tttattttgt tggtaaaata tgaatagatt atagattata
    13741 gattatagat tatagattat agattataga ttatagatta tagatttaag tatagactaa
    13801 gtaatttata ttacagaaga gaatatataa gaattaatgc aagatgtatt tgatacatat
    13861 aagaaattgg caagtccagg agaaggatag agaaaattga gattgaagag tttgaaagag
    13921 attattagat gaaaaataca aaaatgtata aaaatacata ttgagaaagt atatctctct
    13981 taaatttgtt aataattcta ttatacagaa aaacatattt aagggggatt ttttactatg
    14041 aaaaaagtaa aattagctat aagctttttt atattaatga ttataggaat gacaatatct
    14101 tatgcagata caagtataaa tactagatac aatagattaa gtaaagctct tgaaatatca
    14161 gaagcaaatt ttaaatttta taatgttaaa attaattctg ttataaatca taatttatca
    14221 aataaagaat ttcataatat ttttatagaa ataattaaca atctaaagtt ggataaaaaa
    14281 ggaataaatt ggaatcaaaa agggtctggc gataaaatac aattatgtgc tactataaaa
    14341 ggtagcgata aagaaatttc tataaaagga ataaataaaa ataacaaaga aagttacata
    14401 gtagttgaca tattggataa caaagtatat aaacataaag aggttattta tagtaacgta
    14461 gaaaatgtgt taaataaata ttcatctcaa gtagatgtgt ctgcttgtat tgttggagaa
    14521 tacacaaaaa ggttacaaaa caacaaatat gatgatattt tacaaaaaat attatataat
    14581 atgagtgcta agcaaataga tgaagttaaa gacgtaaact ttttatctat aacagcatat
    14641 agtaaagtat taaatgatta tgaattagaa tatttagggg aaaaaattaa tttaaatata
    14701 ggaattaaat ataatgagga tgacggaaaa acactcatat atattgccac accaattata
    14761 aaattagatt attaattatg aggagatcaa aaaatatggc taagataata gtaaaaaaga
    14821 gtaatccact taaaggtagt gttaaaatag atggtgcaaa aaatgcagtt ttaccaataa
    14881 tagcagcgac tttattagca aacggaaaat caacattaaa tggagtacca aatttaagag
    14941 atgttcatgt tatatcagat ttattaagac atgtaggagc agaagttgaa tataaagaaa
    15001 atacacttac tgttgatgca agcaatataa aaacttgtga agctccatat gagcttgtaa
    15061 gaaagatgag agcttctttt ttggttatgg gaccattgct tgctagattt aatagtacga
    15121 aaatttctat gccaggagga tgtgctatag gaacaagacc tatagattta catttaaaag
    15181 gatttaaagc cttaggtgca aagatagaaa tggaccatgg ttttgttgaa gcagcaacag
    15241 aaaagttagt aggaaataaa ttatatttag atttcccatc tgttggagca actgaaaaca
    15301 taatgatggc agcttcttta gcagaaggga ctacaataat agagaatgca gcagaagagc
    15361 cagaaatagt agatttagca aacttcttga acgaaatggg agcagatgtt aaaggtgcag
    15421 gtactaatac tataaaaata aaaggtgtta aagagttaaa aggagcagaa cataatgtaa
    15481 ttccagacag aatagaagca gcaacttata tggttgcagc agctatgaca aaaggtgata
    15541 taactgttga aaatgtttta atggagcatt taaaaccagt tgtagctaaa ttaagagaag
    15601 ctggttgtga aataacagaa atggacaatt ctgtaagagt tgtaggtcca aaagtattaa
    15661 aaccaataga tataaaaact ttaccacatc caggatttcc tacagatgtt caagcacaat
    15721 ttatggctat gcttactgta gccaatggaa ctggtgtagt tatagaaact gtttttgaaa
    15781 atagatttat gcatgttgct gaatttaata gaatgggtgc taatataaaa atagatggaa
    15841 gaagtgcggt tgttaatggt gtagatgagc tacacggtgc agcagtaaac gctactgatt
    15901 taagagcagg ggcagccctt attttatgcg gtcttatagc agaaggagaa actcaaatag
    15961 gagaaatata ccatatccaa agaggttatg ttgatataga taagaagata acagcactag
    16021 gtggtcaaat cgaaatagta gaagattaat aattggttta tagaagaaag ttataaatta
    16081 atagggttgt tcatatactt aaatacaagg ttttaaaagc taaggaggag agtatatgaa
    16141 gaacccattg gttgttttgt taggatttgt gacttgctct gtgttagttc catcacttat
    16201 aactttagtt tcttataaaa atgtagaatt aactgaaaaa ccagagagcc cagtatctat
    16261 aaacaaaact attaaaaaaa gtgatattga agacaaaggt aataaagaag aaaaaaatac
    16321 agtgaactat gaaactgtaa ataaaaaagc accaattatc aatgtatata atcatataac
    16381 agggaaaacc gaaaagatgg acatggagaa ctatttatgt ggagtactag ctggtgagat
    16441 gtcttcagag tttgatatag aagctttaaa agctcaatct gtagcagcta gaacatatgt
    16501 agtatataaa caggaacatg gtaaatctag taaacataaa aatgcagtag tatgtactga
    16561 ttataaacat tgtcaagaat ataagagtta tgatactctt aaaaaattaa atggtgaaga
    16621 atggattaag aataaatatt ccaaaatcca agaagcagtt agaggaacta aaggtcaaat
    16681 aataacttat aatgataagg cgatacttcc tctttatttt tctacatctt caggaaaaac
    16741 agaaaatagt gaagaagtat tttctgcaaa atatccttat ttaaagtctg tggaaagtcc
    16801 ttatgataag tattccccta aatttgcgtc aacacttaaa ataagtaaca cagattttgt
    16861 taaaagtctt agaagggcat atagcactat tgtgatagat gtaaataatt taagtaaaca
    16921 agtttcaata actaaaagaa gtgatgccgg aactgtagaa aaaataaaat taggaaataa
    16981 agaattgact ggaaaagaca ttagaactgt ttttaaattg aactctgcaa actttgacat
    17041 aaaatttgga gaaggataca tagatttcgt ggtaaaagga tatggtcatg gtgttggtat
    17101 gagccagtgg ggagcagaag gaatggcaga agagggctat aaatattatg atatattatc
    17161 acattactac acagatacaa aaataaaaga tatatactaa taattgtata aaatgccaaa
    17221 aacacgtcaa taatccaaat gtagaaatat atttggaggt gcaaaatgaa gaaaaagctg
    17281 ttagaaaaag atggttttta tttatctttg tttgtatgtg tttgtttatt agcagtaggt
    17341 ggagtttggt ttacaaataa taatgtagat aaattggctt ctaataaagg aattatggaa
    17401 aatgctaata aagatagtga agaggaaata catttaattg aaaaagacaa gaaagatgct
    17461 atccctactg caacggattc aaaacaaaac ttagaaaaag ctaagtcaaa agaggaaaat
    17521 aaatcgagta caacaaaatt aaattacatt ggagataaag taataagagg atattcagaa
    17581 aaagagccta gttattctaa aacacttgat gtttgggaaa ctcataaagg tgtagatatt
    17641 agttgtacta aaggcaaaga agtaaaatct ctattaaacg gaatagtagt agatgtattt
    17701 gatgatgaag aatatggaca atcagtcaaa ataaaaagtg acaataacat tgtagtagta
    17761 tattcaaatc tagataaaaa tgttagtgtt aagaaagaac agaaggtaac agaaggacaa
    17821 tctctaggta ctgtaggtag tacttctcaa atagaaagtg aagaaggtat acatgtgcat
    17881 ttagaggcgt atagtggaga aaaatctata gacccaatga gtctaattaa gtaatagtat
    17941 aacaagttta atcatatttg gttaagcttg ttatattttt tggtgttttt acatatatat
    18001 cattaaagct attatgtgag gggggtaatc tttgagatct catatagagg aaagggccat
    18061 agtggtagca aaatatatac ttgaaaaaaa cactacagta agacaaaccg ccaagacatt
    18121 tggagtaagt aaaagtacaa ttcataagga tgttacagaa agattgaagg aaataaatcc
    18181 atcccttgcc aaagaagtta aaaatgtgct ggacaaaaat aaatcagaga gacatattag
    18241 agggggatta gcaacgaaat taaaatatga gaaggaaaat aaaaaaatgt aggttaaaaa
    18301 cctacttttt ttattgaatt aaattataaa aagaaatata ttaagtaatt ataaatagca
    18361 aaataataat actctcaaaa gatttatttt ctcttgatta aagcgagatt tttgtatatg
    18421 ctttattata ggagtattaa aataggctta taatataatc taatattata aataaaggag
    18481 ttgaaaaaat ggctggagct gatataggca tagatttagg tactgcaaat gtgcttgttt
    18541 atgttagtgg taagggaatc gttttagaag aaccatctgt tgtggcgata gacaaaagaa
    18601 cagattctgt tttagctgtg ggagaagaag ctaaaaagat gatagggaga acaccaggta
    18661 atatagtcgc tataagacct ttaagagatg gtgtaatttc agattatgat gtaactgaga
    18721 agatgttaaa atcttttata gataagatag ttgataaaaa gggatttgga agatttttta
    18781 tgccaagaat tatggtatgt gtaccaacag gtgtcacaga agtggaaaaa agagcagtag
    18841 aagatgctac gagacaagct ggagctagag aagtatatat catagaagaa ccaatagcag
    18901 ctgccatagg agctggtgta gacatatcac agcctaatgg taatatgatt atagatattg
    18961 gtggaggtac tgtagatata gctgtaatat ctctaggagg agctgttgta agtgaatcta
    19021 taaaggttgg tggagataga tttgatgatg ctatagttaa atatatgaaa aaacaacaca
    19081 atcttcttat aggagaaaga acagcagaga aaatcaagtt tgaaataggt tctgcattta
    19141 agagagaaga agaaaaatat atgaagataa caggaagaaa tttaattaca ggacttccta
    19201 gttctataac tataaattca acagaaatgt tggaagcact tagagaatgt gttgagcaaa
    19261 tagtagttgc tactcatgct gttttggaaa aaacgcctcc tgagttagca gcagatatag
    19321 gagatgtcgg tataataatg actggaggag gttcattatt atatggatta gataaaataa
    19381 tagaacagag gacaggaata actgttacaa tagcagatga accattatct tgtgttgcaa
    19441 aaggtacagg aatagcttta ggttcaatag acttacttga aactggtggg tctttcaaaa
    19501 gaaaataatt aggagagttt agaatgttaa atatagatga aataaaaaaa ttaataccac
    19561 atagatatcc atttttatta gtagacaaga ttacagagct agaagttggg aaaagagctg
    19621 ttggtataaa gaatgtaaca gttaatgagc catttttcca aggtcacttt ccagaatatc
    19681 ctttgatgcc aggagtacta atagtagaag ctctagcaca agtatgtgga gtggcaatga
    19741 tgtctgtaga ggaaaacaaa ggaaaactag gtgtatttgc aggtatagat aaagttagaa
    19801 tcaagagaga agtaagacca ggagatacat taactatgga agttgaaatg acaactctta
    19861 gaaaaaatat agctaaggca gatgctaagg catatgtagg tgaagaactt gtctgtaaag
    19921 gtgaattaat gtttgcttta gtagaaaaat aaaaacttga aatataaaag taaaaaggta
    19981 gataatttgg agtatttaat cagatactct aaaatatcta cctttttata taaagaattt
    20041 tatcatttag tttatattta gattaggtgg atactaataa agccaaggct attgtttcag
    20101 ctaaatctaa tataaagcta aggcgtatat tattaaatga aagtttatta ttttcatcaa
    20161 ttttatctac aattcctact atagaataat ttcctatttg aggtagtttt ttaccaacac
    20221 cttttccggg caggataggt ccttctctaa tctgtatatt acctatgtta ctctgcgacc
    20281 ccaagcaagc atctatagcc aagaagttac cttgtatatg tgtatttttt atagtatcta
    20341 aagactcata tatatttaag gcgtgaatag ggttatctag tgtaccgtaa acggggtatt
    20401 taaagttact gttcttaagt attgttccaa ctaaagggcc taaagtatca cctatagccc
    20461 tgtctgttcc tatgcaaaca acaatcgtat tttcattaat tatagttttt agaactgaac
    20521 ttagcatctg tataacatca tcatcgctgt agtttacttt agctaaatac aataggaaca
    20581 cccccttcaa aaaaatatat gaataaaaag cattaaaaag acctaacttt aaatttcaga
    20641 tagatagaaa attttatttg tcttacaaaa aaaggaatag aaaaaatatg actaaaaata
    20701 ttgacaaaat tttaaaaaaa tagtaagcta gtaaagtaaa acaaaactta aatcttgatt
    20761 accttatcaa gagaggctga gggataggcc ctgtgaagcc cagcaaccac ccaaatggga
    20821 aaaggtgcta attcctacaa gacaaaagtc ttgaaagatg aggtcagtta attagtatgt
    20881 aattacgatt attaacctct tcttataaag gagaggtttt tttattttga gtaaatttct
    20941 aaaattaaaa ataaggtaaa acctataata aaaattaaga ataaataagg gggaataaaa
    21001 atggcaagac atttatttac gtcagaatca gttacagaag gacatcctga taagatatgt
    21061 gaccaaatat cagattcaat attagatgca ttattagaaa aagacccaca atctagagta
    21121 gcttgtgaaa ctacagttac tactggttta gttttagtag caggagaaat aagtacatct
    21181 gcttatgtag acattcctaa attagtaaga gaaacagtaa gagaaattgg atatacaaga
    21241 gcaaaatatg gatttgattg tgatacttgc gcagttataa cttctattga tgaacaatct
    21301 ggagatatag ctatgggagt tgatgaaggt ctagaaagta agactggaga agagatagaa
    21361 gaagaaatag aaaaagttgg agctggagac caaggtataa tgtttggatt tgcatgtaat
    21421 gagactccag aattaatgcc acttccgata tctttggcac ataaattatc aagaagactt
    21481 acagaagtta gaaaaacagg tttagttgat tatttaagac cagatggaaa aactcaagtt
    21541 actgttgaat atgaaggaag taaagctgta agagtacata cagttcttat atcagctcaa
    21601 cattgtgaaa cagtatcaaa tgataaaata agagaagatt taattaatca tgttattaag
    21661 gaagttatac cagcagaatt acttgatgaa gagactaaaa tttatataaa tccaacagga
    21721 agattcgtta taggaggacc acaaggagat acaggtctta caggaagaaa aataataata
    21781 gatacttatg gtggatattc tagacatggt ggaggagctt tctcaggaaa agaccctaca
    21841 aaagttgata gatctgctgc ttatgcagct agatatgttg caaaaaatat tgttgcggct
    21901 ggtcttgcag acaaatgtga gatagaactt gcatatgcta taggtatagc tagaccatta
    21961 tctatattta tagatacttt tgggacaggc aaggtttcag aagaaaaact tgttgaatta
    22021 gtaaataaac actttgattt aagaccggga gcgataataa gagacttaga tttaagaaag
    22081 cctctttata aaaaggttgc tgcttatggt cactttggta gaactgatat agatttacct
    22141 tgggaaagaa ctgacaaggt tgagcagtta agaaaagatg ctttaggtga ataattttta
    22201 actaaaaagc tgttagaatg taattttatg attactttct aacagctttt ttattatgag
    22261 ttaaatattt ttaataaatg ttaatttatc atcatataat gaataaacag tatttaatct
    22321 ggtcaataca ttttatataa tactctacta aatttataca tattatggga tatatgttaa
    22381 aggatggtta agaatgtgtt aactaatgtt aaataattaa aaatatattg aaatatcaca
    22441 ataatgagtc taatataatc ttaataaact tacactttaa aaataatttt aattgggggg
    22501 gagtagtgta tgtcaggcaa agtaaatatt aaaacggtta taagttttgc tggagcttat
    22561 gttgctactg taataggttc tggatttgca actggtcaag aaatactgca attttttacg
    22621 ttttatggat atgcgggtat tataggtgga ataatctcta tggtactatt ttcatggttt
    22681 ggagcagaag ttatagataa gggaagagaa ttgaaactta aggagccaat aaaaatttat
    22741 caagtatatt gtggaaaata tcttggaaca ttttttgaat ggtttggtcc attgttttta
    22801 tttggaacat tagtaataat gattgcagga gcaggagcta cattatcaga gtactatgga
    22861 ttaaatccat atgtaggtag gattggtatg gcaatcgttt ccctaataac tgtttcatta
    22921 ggtttgacaa ggctttctaa aatactaggt aatataggac ctataataat aatatttaca
    22981 cttttagtag gagcaattag tttatttagc aatattgatg ctttatcaaa tgctggaaat
    23041 atggttgata gtttaaatat taaaactgct acatcaaatg gatatttctc gggagtactt
    23101 tatacttgtt acaatgtaat aatagtaata acattcttga caggaatggg agcttctgca
    23161 gtaaataaga aagatgctgt atggggtggt atagtaggtg gagtagcact tatggcagca
    23221 gctataatga tgaatttggc attactttca gacataggaa atatatacac aaaagagata
    23281 ccagcacttt acttagctga taagatatct ccaataatag gtattttatt ctcagtagta
    23341 cttttactag gaatatacac tacagctgta ccattgttat ggtcagtaac aaaccgattt
    23401 gtagaagatg accaccctaa gtttaaaatt ataacaatag tggtaagtat attagcttgt
    23461 ataggaggtt tactgccatt tgataagtta gtaggtacac tatatccata tacaggttac
    23521 atgggaattt taattttact atgtatgctt tatagaagaa ttactaaaac tgaggggtac
    23581 aaggagaata aatctgaaat aagttagtac tgtaatatac ttatgaaatt taatttatac
    23641 tctaaatata gagtaattaa aataaaatag ctatttaaat atggtacctg tatttcatgg
    23701 taccatattt tatggatgca gatttttttt gtttctgata aaatgtataa tagttggaaa
    23761 ttacgttaag tataaaaata taaaactttt ctacgattat catagtttta atatataaaa
    23821 ttatactaac atttaaatgg agcgattatt agtattttta ggagataaaa atggaaaaat
    23881 tagaaggaat gataagtgaa atagtcttta aaaacgaaga taatggttat acaatagctc
    23941 acctggtaaa tgaaaatgat gaaattgtgg ttgtaggatg tatgcctact ttggcaattg
    24001 gagaaagcat agaagttgaa ggaaagtggg taaatcataa gatttatggg actcaatttg
    24061 aagtgaatag ttttatgcca gtaacaccat catccttaga aggaatttat gtttacttat
    24121 cttctggaat gatacatggt attggtgaaa aaatggcaaa aagaataatt gataagtttg
    24181 gtgtagatac gttagaggtg atacaaaatt caccagaaaa actacaagaa gtagaaggta
    24241 tagggagtaa aaaagtaaaa caaatagtaa aaagttatga agaagacaga gaattgagaa
    24301 atataataat acagctatct ccttttggaa taacaccaaa ttactgccta aaaatatata
    24361 aaaaatataa aagcagtgca atagaagtta taaataaaaa cccataccaa cttgctgaag
    24421 atataagagg aattggattt aaagtagctg atagtatagc aagtaaaatt ggtatagata
    24481 aaaactctaa agatagaatt tgtcagggaa tcttatacac tttaaataaa tctttaagta
    24541 atgggcatac atatttacca gagcatgttc taatacaaga ttcggaaaaa ttgttggagc
    24601 taaatggaga aatactaaaa gagtgtgtaa tgatgctagt ttataatcaa aaaatacata
    24661 tagagaaagt aaacaatgaa aatcttatat accttatgcc atactattta gctgaaaatg
    24721 gagtatgtag tcaaatagta aaattatcac agtatgaatt tgaagactta aaaatagata
    24781 tagataacga gattaatgtt ttagaagaag ataagaaaat taagttagca gaaaaacaaa
    24841 ttttagcagt caaagaatct gttaatagtg gagtattaat tataactggt ggaccaggaa
    24901 ctggtaaaac aactaccatt aatactatca tagatatatt tgaaaataat ggtaaaagtg
    24961 tgactttggc agctccaacg ggaagagcag caaagagaat gagtgaaact tctaataaag
    25021 aagcaaaaac tatacatagg ttgctagaaa tgggattttc aacagatgat gatttaactt
    25081 tttttaagga tgaagaagac ccaataaatt cagatgtaat aattgttgat gaggtatcaa
    25141 tggtagacat tatcttaatg tacaatttac ttagagctat aaagttagga acaagagtaa
    25201 ttttagttgg agatagtgac caattacctt ctgtaggtgc tggaaatgta cttaaggata
    25261 tgattaattc taatattata aatgtagtta aattaaatga aatatttaga caagcgcaag
    25321 aaagtatgat aattgtaaat gcccataaga taaacaatgg agaaccactt tatctaaata
    25381 caaaaggtaa agatttcttt tttataagaa aatcaactaa tgaagaaatt ttaaatgaaa
    25441 taataggatt ggttaatgaa agattaccta aattttataa agttgagaaa ttaaaagata
    25501 tacaagtttt atcttcaatg agaaaaggtg aattgggagt tactaatctc aatatagagt
    25561 tacagaagta tcttaacaaa aaagaaaaat ttaaagttga agaaagtttt tctaaaagat
    25621 tatttagagt tggcgataag gtaatgcaag taaaaaataa ttatacaaaa aaatgggaaa
    25681 cagaagacca aaaagaaagt ggagaaggta tctataatgg agatatagga tatgtttatc
    25741 acatagataa agataagaaa actatttata tattatttga ccagactaaa attgtatcat
    25801 acctctatga tgaattagat gaaattgacc atagtttttg tacaacaata cataaaagcc
    25861 agggaagtga atttccagtt gtagtattgc caatagcgtg ggctcctcct atgttactta
    25921 gccgtaattt attatataca gcagtaacaa gagcaaaaaa attagttgta ttagttggag
    25981 atgtgaaata tcttgaatat atgataaaaa ataatagagt taatcaaagg tattcaaatt
    26041 taggatataa gctaaataaa tttaaacaag aagggttgtt gatagaataa atatgaaaat
    26101 atgcaatgat aattttatta agaattttaa aaatatgatt aataaatgtt tggattttat
    26161 atatcctgag aatataagtt gcataatttg tgataaatcc ataaagaaaa caaatactta
    26221 ttcaatatgt aaaagttgtt ttaaagaaat gaattttata caagatggtt gcatgaagtg
    26281 tggaaaacca ataatacgtc attcaattga aaaagaattt attgaagagt gtagttattg
    26341 ttttaataaa gacttttatt ttgataaatc aatatcttgt attgaataca atgatgtgac
    26401 aaaaaagatg gtgttagggc tgaagtataa ccaaaaaacc tttatggcta agtatatagc
    26461 tcaaataatg aaagaaaaat tatatttaga aaacataaaa tttgattata tattatttgt
    26521 tccacttcat aaaaaaaggc taaataaaag aggttttaat caggcacaaa aaatagcatt
    26581 taatttaagt aaaatagtaa atattccatt attagattgc ataagtagaa aaaaatatac
    26641 aagaatgcta tataaattga ataagaaaga acgaaaagaa gaattaaaaa atgtatttgt
    26701 tgttaaagaa aatgttaaat taataaataa taaaaatata cttttaatag atgatatatt
    26761 tactactggt ctaacaacaa acgaaatttc taaactttta aagttatcag gtgctaataa
    26821 ggtttttgta ttgactctac ttacaaaagc aaatgataat tatattatgg aataatctta
    26881 tatattgaca attttagttt aaaatattaa aatgaataag tgatatttag gtctgtggtt
    26941 gaaagtccaa gccagtcgca ggcaaaggga tccacgtaag ttaacactaa aaattgggtt
    27001 aatgatcatg gtgcggctta gaagtaagac ctaccgataa taaaatcgag agagagtagt
    27061 agtgcggcga acccaagcga accctccagt aggcgagtgt ggggtcaaaa accaggtcag
    27121 ctaaatatca tattaaaaga gagctagcat acctttatgt atagctcttt tttatatata
    27181 ataaatttag gttgagtcat aaagaggtga tatgtttgaa taaaagacaa gaaaatttat
    27241 taacaacatt gctattaaaa gaagagttta taaatgttaa taagattgcc aatgattttg
    27301 agtgttcaga aaggacaata agaaatgatt gcaaatatat tgatgaatgg ttatctactt
    27361 tttgtaatgc ttatatcaaa agaaaaccta atattgggat taaatttagt ggagatggaa
    27421 cagacaaaat actggtaaat cagaagttgc gaggtgaagt taaaagagta aatagtgagc
    27481 ttcataagca agttgagata ttaaatttac tactttgtaa taataaaaaa gttactttaa
    27541 atgatttatc taataagttg tacataaata aaaatattgt cagagaagaa ataagtaaat
    27601 tatcagtagc attaaataat tataatttaa atatctcgac taaaaaaggc agtggtatat
    27661 atattgaagg ggatgagaaa gacataagaa taatgttagt atcattctta tttaaatata
    27721 tagataaata cagattaaac atagatgaaa tagagtactt ccatatagta gatataataa
    27781 ttgtaaaaaa cataatgctt actatagagg aggatatgga tataagactt acagatatat
    27841 cattcaagca attgatgcta tttttgctta taaatataat acgaataagg ctgggaaatt
    27901 ctttaaaagt atcaaatact aagaaagagc ttaagctaaa aatgcttata ttggatatag
    27961 aagatgaatt gaaatctaat ttatccatag tattaaatta tgaagaaaaa ttgtttatag
    28021 aatctttaat attgggtatg aacaaacaaa taaatagtaa taatattaag aaatctttat
    28081 atctaaatga agaattagca agttatacaa aaaaaattat aaatttagta tcagaagaat
    28141 caggaataaa ttttaataat gatatattac tttatgaaca attaatatgt catttgaatg
    28201 ttacaatgca tcaaatgaaa agcaatgttt acttagaaaa tccactttta gataacataa
    28261 aaactaaatt ttgtttttta tttacagtaa tatcaagttc aatagaaatt gaattaaaag
    28321 gaaaacaaat aacggaagat gaaattggtt atcttacact tcactttcaa acctctctag
    28381 aaagaaaata cagcaaaagg gaatcaaata aaaaggcaag tattgtatgt ccatttagtt
    28441 ttggagtaag tatgctatta aaagtaaaga tagaaaagag atttgataac ataaaaatta
    28501 ttgaaacatt aagagaggaa gatttaaaaa gagataactt taataagact atagatttta
    28561 taattgcatt tcaagagtat gaaaatatcc aaaaaccaat ttttataaca acaccattat
    28621 ttactgatga ggatgagaat aaacttaaag agttcacaaa caaaataaaa gaaaaagaca
    28681 cttcatataa acttatgaac agattaatga tgtctgatta tttaataaga gagttagaac
    28741 atgatgatat ttatgaagct ataacatatt taactaattt attaattgaa aaacattatg
    28801 cagaaaaaga gtatttacaa tctattataa caagagaaaa gtcatatcca accaatgttg
    28861 gaaaaggaat attattccct catggagaca tgaaatatat aaaacaatct gttttatgtt
    28921 ttgcaaggtt aaaaacacca ataaaaatta gaaatggaaa ggatataaag attatacttt
    28981 tgttagcata taaaaaagat gatgatagaa aagtatttag agaattattt aaagaaatat
    29041 ctaatttaac agaggatgaa aatatgctag atattctaag taaatgtgac attgaaaagg
    29101 taaaagatat tcttatataa aattcatagt gaactatgga taagcacaaa attttccatg
    29161 tgatggaaaa agttgtgcat gtttttttgt ttttataaga tattatatgt ttgtaaggta
    29221 taaataatct aaaagtagag aagcaactta ggaggaaaaa atggaagaaa tagttttaaa
    29281 gattataatt catgctggaa atgcaaaatc tatgctttat gaggcacttg actatgcaaa
    29341 ggaaaacgat tttaaaaaag cagatgaatt aattgaaaat gcaaatgaag aaattttaaa
    29401 agcacataaa gtacaaactg aacttataca aaaggaagct gggggagata aatcagatat
    29461 atctatttta ttgattcact ctcaagacca tttaatgact tgtatgagtg agagaaacct
    29521 tataaaagaa atgattatgt taagaaaaga aattcaaaaa ctaaaataaa aaattaaggg
    29581 ggatttaaaa aatgaaaaga aaagtatatt tattttgtag ctttggtatg tcaacaagtt
    29641 tacttgcaga taaaatgcag aaggtagcag atgaacacaa tttaccaata gaagtagagg
    29701 catttccgat agcagaaatt gacaaaatag ttgaagaaaa aaatccagat tgtatattat
    29761 taggaccaca agttaaatac atgctaaagg agttaaaacc aaagtttgaa gctcaaggaa
    29821 aacttataga tataatcaat gaagttgatt atggaactat gaatggggaa aaagtattaa
    29881 aacttgctat aaagctaata aaatctaaac aagcgtagaa ttatagtaaa aaataatagg
    29941 aaatgagggt ggatagatga atagattgga aagaatactt atgccattgg ctgaaaaaat
    30001 aggtaaaaat aaattattaa ttgcaattag agatggtttt ttagtatcat caccattatt
    30061 aataataggt tcattatttt tattagtagc aaattttcct ataaaaggat ggaatgaatt
    30121 tgtaggtcaa atttttggtc cagattgggc tgtaaaattg caacaaccaa ctgtagcaac
    30181 atttgaagta atgactctac ttgcagtttt agggattgga tattcttatg caaagcaaat
    30241 agatgtagac ccaatagcat cagcagcagt tgcaatagtt gcctttttta taataacacc
    30301 atttgtaata ccatatacac cagaaggaac agaatcagtt tacatggtaa caggtatacc
    30361 actaggttgg atgggttcta agggaatgtt tgtaggtatg ataacagcaa taacctctgt
    30421 aaaattattt gctgcagttg taaaaaaagg atggacattg aaaatgccag atggagttcc
    30481 tccaactgta tcaaaatcat ttgcagcatt aataccaagt gcaatagtta tggtagtttt
    30541 ctttttagtt aagatagctt ttgaagctac accatatgga agtatacatg aatttatatt
    30601 taagttttta caaatgccat tattaaaatt aggaaatagt ttaggtgcta tggcaatcgc
    30661 ttatatattc ttacatttat tctggttctt tggaataaat ggaagtagtg ttgttggggc
    30721 tgtgtataat ccaatattaa aaattctatc agctgaaaac ttagctgctt ttcaagctgg
    30781 ttcaaaaata ccaaacataa taacaggtca attccaagat atgtttgcga catttggtgg
    30841 agcaggtagt acactatcat tagtcatagc tatgttatta atatgtaaaa gtaaacgtat
    30901 aaagtcaatg ggaaaactat caattttacc aggaatattt ggtataaatg agccattgat
    30961 atttggtcta ccaataatgc ttaacccaat actattgata ccatttgcaa tagttccaac
    31021 aataaatata ataatagctt acttctgtat gtcagcagga ttagtgcctc ttacaaatgg
    31081 agttcagtta ccgtggacaa ctccaattat attctctggt tttttaacaa caggatggca
    31141 aggtgcagtc ttacaattag tacttcttat actaggaata tttatgtata taccatttat
    31201 aaaaatgcta gataagcaat acttgagaga agaaaatgaa actgttgaag aggaagatga
    31261 tgatatatct tttgatgatt tagtattata ggaggaagat tatgaagaaa atagttatga
    31321 tattggacca aatacaagct ggagctggag gaaaagagaa aagtaatata cctcctgctg
    31381 gaaaatcaag cccattagga ccaggtgtaa tgatggagca atttttaaat gaatctaagg
    31441 taatagctac cttattttgt ggggatgaat tttttgtaaa taatcaagaa gaagtaacga
    31501 gtaagatgat agctatggta aaaaaattaa accctgatgt agtaatctgt ggaccaagct
    31561 ttaattacga aaacttttct aagatgtcag caatactgtc taaaaatata aatgataaaa
    31621 cagatatacc agcttttgca gctatgtcag aagaaaatat agatgtgata aacgaatata
    31681 aaaatgacat atgtatagtt aagactccaa aaaaaggtgg aattggtctt aatgattcgt
    31741 taaataacat atgtaaattg gcaaaagcaa tagcaaataa agaagatata actttgatga
    31801 aagaagaatt ttgttattaa taagagtatt aattattagc aagtttaaat attatactat
    31861 ttataataag catacattag taaaatctat ataatttaag gaggggaatt ttaacatgtg
    31921 gggaatgata gcgacatgga gaatggccct agaaggaata actgaggcat cagaacattt
    31981 agaaaaaggc atggaagcag gtgatgctgt agagcttgct gtaagaagag ttgaagacta
    32041 tccattctat aaatcggttg gatatggtgg acttccaaat gaaaattgtg aggtagaact
    32101 tgacgctgca tttatggatg gtaacacatt agatattggc gcagttgctg gtataagaga
    32161 ttattctaat cctgtcagca tagctaggaa gttaagttat gagaaggtaa ataatttttt
    32221 agttggaata ggtgctgaag attatgctca taaaaatgga tttgaaagaa aaaatatgtt
    32281 gactgataga gcgaagttac attataaaaa gagaaaaaaa gagactttag acaaaggatt
    32341 aagcccatat gctggtcatg atactgttgg tatgatatct ttagacaaaa ctggaaaaat
    32401 gtgtgcagct acatcaacaa gtggattgtt tatgaagaaa agaggtagaa taggagattc
    32461 tgcactatct ggttcaggat tctatgttga tagtagtata ggaggagcta cagctactgg
    32521 tttgggagaa gatttaatga agggatgtat atcttatgag atagttagac ttatgaaaga
    32581 agggaagcat ccacaagaag catgtgatat tgcagtaaat gaacttgata aacagcttat
    32641 caaaagaaga ggaaaagctg gtgatttatc attagttgcc atgaataata aaggtgaatg
    32701 gggagtagct acaaatatag ctgattttac tttttcagta gtaactaaag aagaatctcc
    32761 tactgtatat atttcaaata gagtagatgg aaagactata cataaggtta tatcaaatga
    32821 gtggatggaa gcatatgagg ctagaataaa agcaccaata gaagtaagtg agtaaagtag
    32881 tggttacata attaaaatag agttttataa taaggagatt tttatgaata tcataagtaa
    32941 taaaatagat gagttaaaag aagatttatt aagtgatatt atagatattg taaaaatacc
    33001 tagtgtcaaa ggggagtcag aaaatggctt cccttttggc gaaaaagtag gggaggcact
    33061 taataaagca ttagaaatat cagaaaaatt gggatttaag gttagaaact tggataatta
    33121 tattggttat gcagagcatg gagatagtga tgattatgtt tgtgtaattg gacatgtaga
    33181 tgttgtacat gaaggagatg gttggaagca tcagccttat aagggagaag aaactaatgg
    33241 aagaatttat ggacgaggag tactagacaa taaaggacct ataatgtctg ccttatatgg
    33301 attatatgct attaaagaat taaacttaaa attagataag agagttagaa taatatttgg
    33361 tacaaatgaa gaaagtggat ttgaagatat accatattat ttagaaaaag aaaaagcacc
    33421 tattatggga tttacaccag attgtaagta tcctgttgta tatggtgaaa aaggcatggc
    33481 aaagattaga ataaaaagta aaatcaatta tgaagaagat gtatacctag gttttataga
    33541 aaatatgtct gaaaatgtgc ttgttacata taaagagctg aatatagaaa atagtgatac
    33601 tatattagat ataaaggtaa aatacgattt tagttataaa ttgaaagatg tattagatga
    33661 aataaaagct agttttccaa atagtatcga tatagaggta atttctaatt ttaatcctgt
    33721 atattttgat aaagagagta atcttgttaa aaagcttcag ctagcttatg aaagggttac
    33781 atcattagat ggaactccag taacaactaa tggaggtacg tatgcaaaag taatgccaaa
    33841 tatagttccg tttggacctt catttccagg acaaaaagga atagctcata atcctgatga
    33901 atacatggat atagaagata taatattaaa tgcaaagata tttgcaaatg caatatatga
    33961 attagcaaag gagtagttat gttagaaata ataggaatgt cagtagaaga cgctaaaatt
    34021 atagaagatt gtggtgcaga tagaatagag ttagttagtg ctttaactga aggtggattg
    34081 acaccaagtt ttggtcttat agaaagtgtt gttaacagtg taaagatacc tgtgaacgtg
    34141 atgataagac atcatgcgaa aagttttgta tacagtaaag aagatataag tataatgcaa
    34201 aaagatataa gtgtggttaa agagattggt gctaatggag ttgtatttgg tgtattggat
    34261 aaaaacaata gtatagatga gaaaaatcta aatgttttat tgaaatgttg tgataatctt
    34321 gatgttacat ttcatagagc aatagatgaa tcaaatacaa tagatagtgt taaaattttg
    34381 aaggattatg ataaaattac gaatatatta acatcaggag ggaaaggaag tatagttgat
    34441 aacatacaaa tgataaagaa tatgatgctt agttctaatc acataaaaat tcttttaggt
    34501 ggaggtctta attttaataa tatagaaaag ataaaggaat tgactaaggc aagtaatttt
    34561 cattttggta cagcgattag aataaataac agtccttttg aagatataga tagacaaaag
    34621 cttaaacaac tcgtaaatat aatttcaaga tagtatatga atataaaata cttagtttaa
    34681 ataaagagag taagttaatt ataatttggg tatatgaatg ttaataggta ttaaatatga
    34741 aattattgtt gagtatgctt tataactttt aagtagtttt aaatataaat aatgaaagaa
    34801 aagatagatt atggaggttt tagagggttt atatttatta aaaaattata aaggtatatt
    34861 ggcatataat acacataatt tcctaaaatt accatcttat gacatgaatt cacatattaa
    34921 taaacaatta atggagattt ttgtggatag aaataggagt aaaaatagct ttaaataaac
    34981 aaaaacaaga gttattaaca gttttatcca cattatccac aggtgtttgt aataatatta
    35041 atccacataa gtatcaatgt aactaaaaat gataaataat tctatcaatt gaatagaaaa
    35101 aatcataaaa gtaaataata aaaagaggat tatgagagtt cgtgtagaat atattattaa
    35161 agtataaatt ttcttatact ggcataattg aagggagatg tatttatgaa cataattata
    35221 tctggaaaac aaatcgaatt aactgatgca ataaaaaata aaatcgaaac taaactaagt
    35281 aagttagata attacattca tccagacact gatgtaaaag ttacagtaag tgcgagaaaa
    35341 gcaagacaaa aaatagaagt aacaatagct actgtaaatg gtcctataat tagagcagaa
    35401 gatatgcagg aaaatttata cacagctata gatgttgtat atgataaatt aagtaaacaa
    35461 ttaaaaaaat ataaaaagag attacaagat aaacataaag acaacaagag tataagattc
    35521 caagatgcag agataaatct agctgatgaa caagaggatt atggggatga aaatcaagaa
    35581 ttagtaattc aaagacgtaa gaaatttagt gttaagccaa tgagtgaaga agaagctgta
    35641 ttacagatgg aattaatagg acatgatttt tatatgttca agaacataga ttcagatgaa
    35701 atagcagtag tttataagcg taataatggt ggatatggta taatagaaca tgaataaagc
    35761 aatttagatt taatcatatt agctatcgat aaataaatta tcgatagctt tttaaattaa
    35821 tattaaaagt atagttttta tggtaaaatg aataatagta caataaagaa cgaggagaga
    35881 tgtaaaatat gagctttatg gataatttat tcaacatggc agataaaaaa gaattaaaaa
    35941 agttcaataa aactgttgat ataatagatt cattagaacc taaatttgaa tctatggcag
    36001 actcggaact taaaaatatg acaaatatat ttaaagaaag attagcaaat ggtgaaagta
    36061 tagatgatat acttccagaa gcttttgcag tagttagaga agtttctaag agagtgttag
    36121 gacttagaca ctacagagtt caaatgattg gaggtatagt actacatcaa ggaagaatag
    36181 cagaaatgaa aacaggtgaa ggtaaaactt tggttgcaac tgctcctgtt tatttgaatg
    36241 cgcttactgg aaaaggtgta catgttgtaa cagtaaatga ttaccttgca aaacgtgata
    36301 gagaccaaat ggcaaaaatc tatgagtttt taggaatgag tgtaggcgtt attatacacg
    36361 gtcaaaatcc aaaagttaga aaagaacaat atgattgtga tataacttat ggtacaaata
    36421 atgaatatgg atttgactat ctaaaggaca atatggtaat acacaaagag caaagagttc
    36481 aaagaggatt aaattatgct atagtggatg aggttgactc tatactaata gatgaggcta
    36541 gaacaccact tatcatatct ggacctggag acaaatcaac tcacttatat tcagatgcaa
    36601 acacatttgt tttaacctta aaaccagatg attatgaatt agaagaaaaa gataaggctg
    36661 tatctctaac agcatcgggt atacaaaaag cagaagtgta ttttaatgtt gataatataa
    36721 cagatatatc tcatacagaa ttataccatc atataaatca agctttaaga gcacatgtaa
    36781 taatgaagaa agatgttgat tatgttgcta aagatggaga aatagtaata gtagatgagt
    36841 tcacaggtag acttatgttt ggtagaagat attcagaagg tttacatcaa gcaatagagg
    36901 ctaaagaagg tcttaaaata caaagagaat ctaaaacact agctactgta acattccaaa
    36961 attactttag aatgtacaaa aaactttctg ggatgactgg tacagcaaaa acagaagaag
    37021 aagagtttaa agcaatctac aaaatggatg ttttccaagt acctactaat aagcttatga
    37081 taagggaaga cttaccagac tgtgtataca aaagtgaaat aggtaaattt aatgctgtag
    37141 cacaagaaat aattgaaagg cacaaagtca atcaaccaat acttgtaggt acagtatcaa
    37201 tagaaaaatc agaattatta tcacaaatac taaagaaaaa gggcataaag cacgaggtat
    37261 taaatgctaa gcatcatgat aaagaggcag aaataatagc acaagctggt agacttggag
    37321 ctgttacaat agctactaat atggctggtc gtggtacaga tatagttcta ggtggaaatc
    37381 cagacttttt aactaagaga gaaatgagaa gaaatggatt taaagaagaa atagtaaata
    37441 gagtagatac tccaatagaa ggtatacctg taaaaggtaa tgaaattcta tttgaagcta
    37501 gagaagagta tgaaaaacta tttgaaaagt ttaagcaaca aacacaagaa gaacaaaaac
    37561 aagttgtaga agcaggtgga cttgctataa taggtacaga aagacacgaa tctcgaagaa
    37621 tagataacca gttgagaggt cgtgctggac gtcaaggtga cccagggagt tcaagattct
    37681 atataggtct tgatgatgac cttatgagat tgtttggtag tgatagaata tctggtattg
    37741 tagataaaat aggtcttgaa gaagacatgc cgatagaaca tagaatatta tctaagtcta
    37801 ttgaaggagc acaaaagaaa gtcgaaggta aaaactttgg aataagaaag catgtacttc
    37861 aatatgatga tgttatgaat aaacaaagag aaataatata tgcagagaga aaacgtgtat
    37921 tagaaggtga agatttacaa gaacaaatac aatcaatgac tcattctata atagaagaag
    37981 cagttactct ttatacacaa gataaaggat ttgatgaaga aggattcaaa gaacatatgt
    38041 ataatctgtt cttgccaaaa ggtagcatag aaataccaga aatagaaaaa cttaatccag
    38101 ttgaaataac agaaaaagtt tatgaaatag ctatgaagat atatacttca aaagaagaac
    38161 aagttggcta tgagagaatg agagaagttg agagagtaat cttacttcaa gctgttgata
    38221 accattggat agaccatata gatgctatgg accaattacg ccaaggtatt ggtcttcgtg
    38281 ctgtaggtca gcaagaccca gttattgctt ataaaatgga aggttttgat atgtttgatg
    38341 aaatgaataa acatatcaaa gaagatactg taagatattt atttaatata acaatagaaa
    38401 ctccagtgga aagaaaagca gttgtagatg ttgaaaatct atcttctcca tcagatggaa
    38461 cacttccaac aagtaaaact gttaaaaaag atgaaaaggt tggaagaaat gacttatgcc
    38521 cttgtggaag tggtaaaaaa tataaaaact gttgtggaag ataatctcgg aggattaaat
    38581 gttaaagtta caagagtata gacatagtat ggagcagatg gcttcaaatt tagaagaatt
    38641 gagggtttct ctttgacata gcttcattga tgaaaaatat acaaattaat gaagaaaaga
    38701 tgaatcaaca agatttttgg aatgataatg aagtcgctca aagagtactt caagaaaata
    38761 aatctttaaa agagacatta gaagaatatg aaagcttaaa aagcttatta gaagatatag
    38821 aagtattaat tgaaataggt ttagaagaag atgatgattc tgtagaaaga gatatagaaa
    38881 agtccataga atcaatggaa gaaaaattat ctgaaatgaa aataaagact cttctaaatg
    38941 gagagtatga taaaaataat gctatattat ctataaatgc tggtactggt ggcttagatg
    39001 ctcaagattg ggctcaaatg cttttgagaa tgtatataag atggtcagaa agtaagggtt
    39061 ataaagttaa gcttttagat ataatatcag accctgaagc agggataaag acagctacaa
    39121 ttcttgtaga aggaacaaat gcttatgggt atttaaagag tgaaaaagga gttcatagat
    39181 tagtgagaat atctccattt gacccatcag gaaaaagaca tacttcattt gcatctatag
    39241 atgtaacacc agagttagat gaaaatatag aagtagaaat taatccatca gatttaaaga
    39301 tagacacata tagagcttct ggagctggag ggcaacatgt aaatacgact gattcagcag
    39361 ttagaataac acatatccct actggtgtag tagttcagtg ccaaaatgaa aggtctcagc
    39421 atctaaataa ggacagagct atgagacttt taatggcgaa attgatagaa ttaaaagagt
    39481 tagagcaaaa ggaaaaaata gaagatatac aaggcaaata ctcacaaata acttggggta
    39541 gtcaaattag gtcatatgtt tttcaaccat ataaattggt taaagaccat agaacaaatg
    39601 ctgagtttgg caatgtagat agtgtaatga atggaaatat agacttgttt attaatgaat
    39661 acttaaaaat gaataaaata gtttaataaa tatgcactgt aattaagata tatgtataag
    39721 aaggttagtg cttaatatgc acttacagca cttaggctga ggacgataac cctcagcctt
    39781 cgttctgttt tgttatactt atgaaaaact aacattagga gtgaataaat tggatataaa
    39841 tcaaatctta aaaaaagagt ttaatcttag agatgaacaa ataaataata cattaaaact
    39901 tattgatgaa ggaaatacaa taccatttat agctagatat agaaaagaaa tgactggcga
    39961 aatgagtgat gttacactaa gagaatttta tgaaaaatta atgtatttga gaaatcttca
    40021 aagtagaaaa gatgatgtag ttagactaat agatgaacaa gggaaattaa cagatgaaat
    40081 aacacaaaat atagaaaaag caaaaacatt acaagaagta gaagatatat atgctccata
    40141 caaacaaaag aaaagaacga gagcaacaat agcaaaagaa aaaggattag aaaatttagc
    40201 attgtcaata ctagagaata atttagataa tatagaaata gagtcaaaga attatcttga
    40261 tgaagagaaa gaagttcttt ctattgaaga tgctctaaaa ggtgctagag atataattgc
    40321 agaactagtc tcagatgatg ctaagattag aaagtatata agagaattag ctttaagaga
    40381 aggtatgata gttagcaaaa gtgctactga tgagaaatcg gtttatgata tgtattatga
    40441 ttatagcgaa gcagtaaaaa gtatggctcc acatagagtt ttggcaataa acagaggaga
    40501 aaaagaaagc ttcctaaagg ttaagttgga aataaataat gataaagttt taaattacat
    40561 aataaacgaa tatgtaaatg ataaaaattt caaaaataaa gaagaaatcg taagttcaat
    40621 agaagattct tataaaagat taattttccc atcaatagaa agagaaataa gaaatcattt
    40681 aacagaaata gctcaagaaa gagctataag tgtatttgga aagaatgtta aaagtttatt
    40741 gcttcaacca ccagttaaag acaaagtagt tatgggattt gaccctgcat ttagaactgg
    40801 atgtaaaata gctgtagtag ataaaaatgg taaactacta gattatacaa cagtatatcc
    40861 aacagaccct caaaatgatg tagagggagc aaagaaagtt ttaaaaggat tgattgaaaa
    40921 atacgatata gatataattt caattggaaa tggtactgca tctagagaat cagaaacttt
    40981 tgtatcagaa atgataaaag aaatagatag cgaagtgcag tatgtgatag ttagtgaagc
    41041 aggagcatct gtttattcag catctgaact tgcaaatgag gaacatccag atataaatgt
    41101 atcaataaga ggagctatat ctatagctag aagattacaa gacccattag cagagcttgt
    41161 aaaaatagac cctaaaagta ttggtgttgg tcaatatcag catgatttaa acaaaaagag
    41221 attagaagaa gtactagatg gagttgttga agattctgta aatagtgttg gagtagattt
    41281 aaatactgca tcatactccc tactagaaca tgttgcagga ataagtaaag ctatagcaaa
    41341 aaatataata gcatatagag aagaaaatgg agattttacg tcaagagcac aattgaaaaa
    41401 agtaaaaaga ctaggacctc aagcatttac tcaatgtgct ggatttatga gaatcttaga
    41461 gggtaaaaat ccactagata atacaggtgt gcatcctgaa agttatgata tatgtaaaaa
    41521 aatgattgag ataattggat attctttaga tgatgtaaag aataagaata taggtgaaat
    41581 agatgaaaaa ataaaagaaa ttggcttgag ggaattaagt gaaaaactgg aagtaggaca
    41641 agttacatta aaagatatca tagctgaaat caaaaaacca ggaagagacc caagagaaga
    41701 aggtataaaa cctatactta gaactgatgt cttaaaaatt gaagatatac aagagggtat
    41761 gactttaaaa ggtacaataa gaaatgttgt agactttggt gcatttgtag atattggaat
    41821 aaaaaatgac ggattagttc ataaatcaga aatgagtaat agttttgtga aagaccctat
    41881 gagtattgtt acagtaggtg atatagtaga tgtaaaagtc attggaattg acttaaacaa
    41941 aaaaagagtt gccttatcaa tgaaaaaata gataagttta tgtatggtta taatacttag
    42001 attctatatt tgtaaataag attactcgag tgtataaatg ttaaaaattt gtaaaagtat
    42061 atagtaagaa aatatattaa aataagaacg atagtcttga aaatcaggag gaaaatgaat
    42121 gatttttata aaaaatggta aaataaatac cataacaaat gggataattc atggagatat
    42181 acttatagat gaaggaaaaa taatagaaat tggagaagat ttgatagctc ctttagatgt
    42241 agaggtaata gatgctagta ataaacttgt gtttcctgga tttatagatg ctcatactca
    42301 cttaggttta tgggaagatg gtatagggtt tgaaggagca gatggaaatg aagagactga
    42361 cccaataaca ccacaattaa atcctataga tggaattaat ccaatggata gaacttttaa
    42421 agaagctttt gaaggtggaa taacttctgt ttgtacaacc cctggaagtg caaatgttat
    42481 gggtggtcaa tgtatagcta taaagacatg tggaaaaaga attgataaaa tggtaataaa
    42541 aaatccagtt gcatctaaaa ttgcttttgg agaaaatcca aagagctgtt atggtcagga
    42601 tgataaatct cctcaaacta gaatggctat agctgcttta cttagagaaa acctaaaaaa
    42661 agcagaagaa tatttagagg atattgatat gtatgagagt catgatgatg aagactgtga
    42721 aaaacctgaa tatgatataa aaatggaaag tttaatacca gttttaagaa gagaaattcc
    42781 ttttaaggca catgctcata gagcagatga tatgtttaca gcaataagaa ttgcaaaaga
    42841 atttaattta aagcttacat tagaccattg tacagaaggt catcttattg tagatgaatt
    42901 agtggaagaa gggtttcctg taatagtagg gccatcttta tcagaaaggt ctaaatttga
    42961 gcttagaaat ttgacattta atacagcagg aatactttca aatgcaggtc ttgatgtatg
    43021 tataatgaca gaccatccag taataccagt tcaatatctt ccaatatgtg caggtattgc
    43081 agtaaaacat ggtatgaaag aagaaaaagc aatagaatca attacgataa atccagctaa
    43141 gactttagga atagaagata gagtaggctc tatagaagtt ggtaaagatg cagacctagt
    43201 aatttgggat aattctccac tagagattca aagtaatgta ctttacacta taataaatgg
    43261 caaagtagtg tatgagaaaa aataacttga caattattaa aaaattaact aatataagag
    43321 tgtaaggaaa attaaaaaat caaagaagat cttcggggca gggtgaaatt ccctaccggc
    43381 ggtatagccc gcgaactact taagtggttg atttggtgag attccaaagc cgacagtaaa
    43441 gtctggatga gagaagatat ttatggaaga taaataagtt tattttagtt tgtttaaact
    43501 atatccataa aaactcgaag atagggtctt cgagtttttt gtttttccta aaaaatataa
    43561 acatattgat tagggggaaa ataattatgc aaaacacagc aaaaagaggc aatatgattt
    43621 caacaagaac tttagtagta atgtcaattt tatctgcaat atcttattta ttaatgttta
    43681 ttcaagcacc aataccaggt atatttccag atttcttaaa aattgactta tcagatattc
    43741 cagcaatatt cggaggaatg tctctaggac cattagttgg atttggaata gttgtagtaa
    43801 aaaatgtgtt acaagcaata acagcaacaa caactggagg aataggagaa tttgcgaata
    43861 tattaattgg tggttcttat gtaatgatac tttgttattc atataagaga agtggagatt
    43921 taaaaggtgt actgattggt tttgtattag gaacaatatc tatgactata attggttcat
    43981 tagtaaatta ttttgtaatg ttgccacttt atggtcaact tatgggacta gatgctataa
    44041 taggtttagg ttcagctata aatcctcaag ttcatgattt attcactttt gtaatttgga
    44101 tgatagctcc atttaatgtg ctgaaggctg ttataatatc tttagtaaca ttgccacttt
    44161 ataaaaaaat gggaaatata ataaagaaat aattagacaa gaaaatataa aattaaatgt
    44221 attgaatagc cataatttat ttataacttc agtcctatat tgtgattgat atattaaata
    44281 tattatggct ttattaattt atcaaaaaat gtatataaaa taagaaatat ttagacaaat
    44341 ttaaatttta aaataaagga agaattaaaa cgattaacta ttaaaatatg aaaaaggtat
    44401 ctacaatata cagagcgaat ttataataaa caaaaaataa agttattatt aaaaaactat
    44461 aaagattaat aatcaaactt ttaataataa ctaatttaat aatgataggg gtgtatattc
    44521 atgcatttat ctaaaaaaat aaaaaaatta tttttagatg ataaagggta ttattttaat
    44581 agtaattgga aagatattca tattggtatt tatgatacaa aattaggaga ttctttaaag
    44641 tatatcacta atgaatatat tgaaaatatg gaaagggtaa aatacgatta tcgtgaatta
    44701 aaaaatatag aaaatcaaac tgatggtatg tgtattttag caataaggca gaattacaag
    44761 gcattagagt atgtaaaaaa tcaaaccgaa gaattatgtt tagaagcaat aaagtataat
    44821 tataaagcac ttgaatatgt aaaagaacaa acagaatact tgtgtcttga agctataaaa
    44881 aaagattgta atgcacttaa gtatgtacga aataaaacag aagggcttat tataaaagca
    44941 ataagtcatt cttccaatat agatgttgta agtatactaa aggctttaga gactcaaaca
    45001 agaaggatat gtttagaagc aattaaaaaa gatggcaggt gtcttgcata cgttagagaa
    45061 cagagtgaag aattatgtat agaggccatt aagcaaaatt ataaagcatt aaaatatgta
    45121 aaaaatcaaa cggaaaaaat gtgtatagaa tccgtaagac aaaatggtat ggcattacaa
    45181 tatgtaaata aacaaactga taaaatatgt atagaagctg tcaaacaaga tggaagaagt
    45241 atacaatttg tcaacaataa gacagaagaa atatgtataa atgctataag atatttaaat
    45301 aaaaaatata atattaaaga tgtactaagt tacatagata agtatacaga agatatatgt
    45361 atagagattg taagacaaaa tggaaaaatg cttatgtata taaaaaatca aacagaaaaa
    45421 atgtgtattg aagcagtaaa agagaactat aagtctctta agtatgtaaa agagcaatct
    45481 gagagaatat gtaaagaagc attgaagcaa aaccataaag caaaagagta tgtaaaaatt
    45541 gctattgatg attgtatata aggtgtagat acagccatca atagtgaaag ataaaaaaag
    45601 ataaagacaa gtactttata ataatctagg cttatactat aattaattaa gcagtgatat
    45661 aaattcacat gacgattata tcaaaatgga gatgaattga tggcaaaaat atatttagaa
    45721 aatgaaaata aaactagaga aataggatat aaattaggta aacttttaaa agaaggcagt
    45781 gttatctgtt tagtaggaga tttaggagct ggtaaaacta caatgacaca aagtttggca
    45841 gattcattag ggatagaaga ttatataaca agtcctactt ttactataat aaatgaatat
    45901 gaaggaaaaa tacctttgta tcattttgat gtttatagaa taggtagtag tgacgaaatg
    45961 tatgatattg gttatgatga atatgtaaat tcaaatggaa tctgtataat agaatgggct
    46021 aatctaatag aagatatact tccaaaagaa tatttgaata tagaattgag atataaagat
    46081 gaaggaagag aaatgatatt aactccaaaa ggagagtttt ataaagagat agttgaggag
    46141 ttgattaaat aatgaaaata ctaggtatgg atacgtcttc tatggcagca agtgtagcag
    46201 ttgttgaaga tgataactta atatgtgagt ttacagtaaa caacaaaaaa actcattcac
    46261 aaaagcttat gccaatgata gaaaatatgt tgagtatgag tgatttaagt ataaaagata
    46321 tggatttatt agctgtatgt ataggtccag gttcgtttac aggacttaga ataggtatgg
    46381 ctacagtaaa agctatggcc catgtaaata atataccaat aatagcagta aattctttgg
    46441 aatctctagc aaataacata aatttctgtg atagaaagat atgttgtata ttagatgcgc
    46501 agaaaaatca agtttattca gctaaataca agtttgaaaa tggagagatg atagaattag
    46561 atggtgttga tgttgtagat tttgatgctt tagtagatga aattgtatca actaatgaag
    46621 aatttataat agttggagaa gctgtataca aatataaaga caagttagag aatataaaaa
    46681 atataaaaat accttcacca gctaataatg tatctaacgc aggaagctta tgctctttag
    46741 cattaaataa atataataaa aatatagatg tacatacttg ttatacgata aatcctatgt
    46801 atatcagaaa atctcaagct gaagtacaat atgatgaaaa aatgaagagg ctaaataatg
    46861 gaagataata caaaactaat agtagatgat ataaaaatag aagaaatgac tacagaagat
    46921 atagatgaag tttttgaagt agaaaaaaat tgttttgaag attattggtc aaaagagtct
    46981 tttagaaaag agttgtctaa tgaagtagca aggtatatag tagctaagtt aaatggaaaa
    47041 attgtcggat atgtgggaat ttggcttata cttgatgaag ggcatataaa taatgtggct
    47101 gttcatagtg actatagagg gaaaaaaata ggggacaagt tgataaaagg catagttgat
    47161 ttatgtaaag ataataatat tgcatctatg acattagaag ttagagcatc aaataaaata
    47221 gcacaaaatt tatatagaaa atatggattt aaaatgggtg gaataagaaa agaatactac
    47281 agtgataata aagaagatgc aattataatg tggaaccaat taaaagaggt gtagagttta
    47341 tgagtgatat aataacatta gctatagaga gtagttgtga cgaaacagct gcatcagttt
    47401 taaaaaatgg tagagaaata ctttcaaaca taatctctac tcaaatcgag acacataaaa
    47461 aatttggtgg tgtagttcca gaagtggcct caagaaaaca tgtggaaaat attgatatag
    47521 ttgttcaaga agctttagac aaagcaaata taggttttaa tgatatagac catatcgcag
    47581 ttacatatgg acctgggcta gtaggtgctt tattggttgg tctatcttat gctaaagcac
    47641 ttgcatatac tttgaatatt ccacttgtag gagtaaatca tatagaaggg catctaagtg
    47701 caaactatat agagcataag gatttaaaac ctccttttat aacattaata gtatctggag
    47761 gtcatactca cttggttgaa gtaaaagatt atggcaagta tgaaatttta ggaaaaacaa
    47821 gagatgatgc atctggagaa gcatttgata agatttcaag agcgatgaat ttaggctatc
    47881 caggaggtcc tattattgat aatctggcca agaatggaaa taaacatgct atagaatttc
    47941 caagagccta tttagaagaa gatagctatg attttagttt tagtggatta aaatcttctg
    48001 tattaaatta tctaaatgga aaaagaatga aaaatgaaga aatagtagtt gaagatgtag
    48061 cagcatcttt ccaagaggct gtagtagagg ttttatctac taaagcacta aaagcagtaa
    48121 aagacaaagg atacaatatc ataactcttt ctggtggggt tgcttctaat tcggggctta
    48181 gagctaaaat aacagagctt gctaaagaca atggtattac tgttaagtat cctcctctaa
    48241 ttttatgcac agataatgca gctatgatag ggtgtgcagg atattataat tttataaatg
    48301 ggaaaacgca tgatatgagt ttaaatgcag ttccaaattt aaagataaat cagtagagtt
    48361 agatgaattt gtaaatataa aagtattgtt tcaaaaaagt aagtagaagt gaaattaaat
    48421 ataataaaaa taaatatagt atatattaaa acttgaagta aaactattta taatctttat
    48481 attccaatga attgcaacaa attttaggat atacagattg tctttggctt agatttgctt
    48541 caagtttatt tttttctata gaaagattat tttaaaaagt gggtaatata cccttttttt
    48601 tcattcttaa aaagttttat actaattata gaaagattaa ggaggggaag aaatgagtca
    48661 aagtaaagaa gacaaaataa gaagtatttt ggaagcaaaa aatattaaat caaattttca
    48721 aaataaagaa aatttaagtg aatttaatga aaaaaaagca agtaaaagag cagaagactt
    48781 attagatgta tattataata cattatctac tgctgatatg gaatttccat attggtataa
    48841 tagagaatat agaaaatcag atggtgatat accagtagtt agaagagcta aagctcttaa
    48901 agctgctttt tcacatatga caccaaatat aatacctggt gagaaaatag taatgcaaaa
    48961 gacacgccat tatagaggtt cttttccaat gccatgggta agtgaaagtt tctttgttgc
    49021 tcaaggagaa caaatgagag aagaggcaaa gaaattagcc agtaacacag ctgatgaact
    49081 tacaaaattt gggtctggtg gaggaaatgt tactgaaagt tttggaaatg tcgtttcaat
    49141 agctggtaaa ttcggaatga gaaaagaaga agtacctgta cttgtaaaaa tggcaaagga
    49201 atgggttgga aagtctgttg aagatttagg ttttcactat gaaaaaatga tgccagatta
    49261 tgatttaaaa gaaaacctaa tgagtacact tatatgcatg tttgattcgg ggtatacact
    49321 tcctcaaggt agagaagtta taaattattt ttatccttta aattatggat tagatggaat
    49381 tatagaaatg gcaaaagaat gtaaaaaggc agttgcagga aatgcatctg gagatgggct
    49441 tattggtatg gaccgtctat atttttatga ggctgttatt caagttattg aaggattaca
    49501 aacttggatt ttaaattatg caaaacatgc aaaatattta gaaagtatag agacagattt
    49561 agaagctaaa aaagaatact cagatttagt ggagatatta gaacatattg cacataaaca
    49621 acctcgtaca tttagggaag ctcttcagtt gacttataca attcatatag catcagtaaa
    49681 tgaggatgct atatctggta tgtctatagg acgttttggt caaattttat atccttggta
    49741 tgaacaagat atagaaaaag gactaattac aaaagaagag gttatcgaat tattagagct
    49801 ttatagaata aaaatcactt gtattgactg ttttgcttca gcgggggtaa atggaggagt
    49861 actatcaggt aatacattta atactttatc tataggtgga ttaaaagaag atggttctac
    49921 aggagctaat gaactagaag agttattatt agaagcaagt atgagatgta gaactcctca
    49981 acctagttta actatgctat atgatgaaaa gcttccagaa gatttcttaa tgaaagctgc
    50041 tgaatgtaca aagcttggtt ctggttatcc agcatgggta aacaactcaa atggaacaac
    50101 atttatgatg aaacaatttg ctgatgaagg tatgactgtt gaagaagcaa gagcatttgc
    50161 attaggtgga tgtttggaaa cgtctccagg gtgttggaaa cagttaactt taaacggaaa
    50221 aacgtactct attgcaggtg gagcaggtca atctgctggc tctggagttc actttatagc
    50281 taatccaaaa attttagaac ttgttcttat gaatggtaaa gactatcgta tgaatataca
    50341 agtatttgag cctcataata agccattaga tacttatgaa gaagtcatag aagtatttaa
    50401 agattattat aaacaagcaa taaatgtttt agaaagagca aataacattg agttagatat
    50461 atggagaaaa tttgatactt ctataataaa ttcactacta aagccagact gtttagacaa
    50521 aggtcaacat ataggaaata tgggatatcg ttataatgca acattaaacg tagaaacttg
    50581 tggtactgtt actatggtca attcatttgc agcgcttaag aaacttgtat atgatgacaa
    50641 agcatttaca atagaggaaa ttaaggatgc catattaaat aattttggat ttaaagatgc
    50701 attagaagta ggaaattatt ctatggcaga ccaagtaaaa gtagataaga ctggtaaata
    50761 tgatgctatt tataaggcct gtcttgatgc acctaaatat ggaaataatg atttgtatgc
    50821 agataatatt cttaaaaact atgaggtatg gttatcaaaa gtatgtgaag aagcacaatc
    50881 tttatatgct aagaagatgt acccttgcca aatatctgtt tctacacatg ggccacaggg
    50941 agctgctacc ttggctactc cagatggtag actaagtgga acaacatatt cagatggttc
    51001 agtctctgca tatgcaggaa cagataaaaa tggagtatat gcattatttg aatctgcaac
    51061 tatttgggac caagcagtag ttcaaaattc tcagatgaat ttaaaacttc atccaactac
    51121 tataaaagga caacaaggaa ctaaaaaatt attagattta acaagaagtt atttaagaaa
    51181 aggtgggttc catattcaat ataatgttgt agattcagaa accttaaaag atgcacaaaa
    51241 aaatcctgac aattatcgtc aattaatggt acgtgttgct gggtttactc aatattggtg
    51301 tgaattaggt aaaccaatac aagatgaagt aattgctaga acagagtatg aaggggtgta
    51361 aaatatgaga aagcatagtg attgtatgaa tttttgtgca gtagatgcaa ccaaaggaat
    51421 ttgtagatta tcaaaacaaa tgattaattt agatgatgca gcatgtccag agataaaagt
    51481 aatgccaaaa tgtaaaaatt gtaaaaattt tgttgaagct aatgatgaag gtataggcaa
    51541 atgtgttggc ctagagaaag aagattgggt atattcaaca ttgaatgcaa ttacttgtga
    51601 aggacatgtg tttaatgagt agtcaaaagc aattagaagg catgattttc gatgtacaaa
    51661 gcttttcagt tcatgatggt ccaggttgta gaacaactgt atttttaaat ggatgtccac
    51721 tgagttgtaa atggtgtgca aatccagaaa gttggactgt aagaccacat atgatgttta
    51781 gtgaattatc ttgtcaatat gaaaatggat gtactgtatg tcatggtaag tgtaaaaatg
    51841 gtgcattgag ctttaatctt gataataagc cagttataga ttggaacatc tgtaaggact
    51901 gtgaaagttt tgaatgcgtc aactcatgtt attataatgc gtttaaatta tgtgcaaaac
    51961 cttacactgt agatgaactt gtgcaggtaa ttaaacgtga ttctaacaat tggagaagta
    52021 atggaggagt aacatttagt ggaggtgagc cactacttca gcatgaattt ttacatgaag
    52081 tattattaaa gtgtcatgag gtaaatgtac acactgccat tgaaacgagt gcatgtgtat
    52141 caaatgaagt ttttaataaa atatttaacg atattgattt tgcatttatt gatataaagc
    52201 atatggatag agaaaaacac aaagaacaaa caggtgtgta taatgattta atattagaaa
    52261 atatatcaaa ccttgcaaat tctgattgga atggaagatt agtacttaga gtaccagtta
    52321 tctctgggtt taatgatagt gatgaaaata taagtgatat tatatctttt atgcacaaaa
    52381 ataatttggt agaaattaat ctattaccat ttcacagatt aggagaatca aaatggactc
    52441 aattaggcaa ggaatatgag tattctgata agggtgatgt tgatgaaggt catcttgaag
    52501 aattacaaga tatatttttg gataatggta tagcttgtta tgttggtcat gagacagctt
    52561 tctaaaatta aatacaagtt ttaattaaaa aaggatgtta cactaaaagc tagagttaca
    52621 tcctttttta tgtggttttt atgtagaaat aattaagtaa agttttatat gttttatata
    52681 ttgtttatat tgctttatgt ccataaatat tgctttaaat atactttata tattttttat
    52741 agtttaaatt acagttagag aatatattac gtttacttta ttgaagcaga agttttgtgg
    52801 taaaatacta ctatgaaaaa atttaataga atatatttta gaaacaacta aaaataatag
    52861 ttaggaggaa gacatctata tgaacaaatc atggagcaac ttgattatta agaataaaga
    52921 cagaaaagta cgttcagggt ggattattat agctgttatg gctacctttt acatacttca
    52981 gtattattta agcatgatac ttgtggaaat aataagaaaa atcctggttg ctacaggtga
    53041 cattaattta aaaacaaact atttttcaga atatgctaat tggttaaatg atgttgggtt
    53101 acagattgta tttcaaattc taacagattc acttatgatt attattccta taattgtatg
    53161 gagatttatt atgaaaaatc ctattagtga aatgggatta cattcttata gaattaagaa
    53221 aaaagaagga tatgtaggaa tgttattagg aatatttaat tgtacagtaa tctttattat
    53281 aacaataaca attggtggtg gtcatgttac ttcatgggta ccaaaaattt cacctttaac
    53341 agtttcttgg atactggtct ttattttagt tgcttttgca gaagaaattt taaatcgtgg
    53401 tttttttatg gcagttttac gaagatgtaa aaatatttat tttataatga ttgttccatc
    53461 tgttattttt gggttgattc atatatggaa tcctgatgtt acttttttgt ctgtaattaa
    53521 tattataatt attgggattc ttttttcata tatgtttata aagtcgtcga atatatggat
    53581 gtgtataggt tatcatttta catggaatgt atttcagggg attatatatg gtatgcctgt
    53641 aagtggactt caggttccag ggattataac tacacaaatc actcatggta atctattaaa
    53701 tggagggatg tttggtattg aaggtggaat tttgactact tttgttaatc tacttagctt
    53761 tatatttgta tggtattact atagagattc taagtatgat tttgttagtg ataaagtaaa
    53821 tgtgaccaat atcaagaatt agttgattat aataaatttt aataatatct tctaagctta
    53881 aagtattctg taggattgtt ggaaatttgc aaaaatataa aaataacttg gatattctat
    53941 ttactccaag ttatttttat attcttttgt aaatagaaat ggaacataaa aaattaaaac
    54001 aaccatagat actattagta tatcatggta agtgatagtt gattctttag aatttgtgat
    54061 aagaaaagca ctattattta aaacatgaat tatagcacaa aaccagatat tcttagtttt
    54121 tatataaaga tatcctaaaa atattgaaat tccaactata tgtattgaac gtaatattat
    54181 tcctaatatt ggcgcttcag gtgtatataa tgtaaatatt agtggtaagt gccacaagct
    54241 ccaacacata cctaatatta taactcctaa ctttttacca aatttatcaa aaaaaatatt
    54301 ctgtaaaaaa cctctccagg catattcttc actaaaaaaa atataaatag tagttaatga
    54361 tgttattgga gtaaatataa attttatgat accactataa ttaggttgag ccccttgtag
    54421 tattagtata aatgatgttg gaacaattac agaaatcata aagtaaataa ttaataaaga
    54481 acctagttta atatttttta caggatataa atttttttta tttgatgaat atattataat
    54541 tgataagcta cttataaaaa ttaatattag gtttataatt ataaattcat tattatttat
    54601 tagatttaat aacttaagaa caattaataa tgaataaata agaaaaaata atatgattag
    54661 tgaataaaat tcatacatat cattatttaa tccttcagta taaaactttg caatagcaac
    54721 tgaagataga ggtaatatca tcatgaatga tgcaaagttt tctggatcaa taaatttatt
    54781 ataatataac agtaaaccta atgaataagt taaatcaaag tttataaaga aaaagataat
    54841 aatttgtatt ttttttcttt ttatttcatt tttaataaat actgggttta gaatatttat
    54901 ccatattaat tttaagttca ttaatttaat actcctttac aatatagatt cttaactaaa
    54961 ttaaaatatt ttattgaata t
//
LOCUS       DAMJXI010000020        53259 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.021, whole genome shotgun sequence.
ACCESSION   DAMJXI010000020 DAMJXI010000000
VERSION     DAMJXI010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 53259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53259
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.021"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            57..866
                     /locus_tag="PC465_001596"
     CDS             57..866
                     /locus_tag="PC465_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2648913.1"
                     /translation="MKDYYKIGEISKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNI
                     SDIWKLNLIKEFRSLNFPMKKIKEYLDDRSIESTKNILNEELDLIDKKIAEFISHKEN
                     IIKRLSSIESVIQNTKIDEIEVVYIEKRKALELNADIKRDEDFDFLIQKLQKEYEDRF
                     NILGNNNIGSAFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNS
                     NNKMYMEKVFKFIEENNYKIIADPIEIYKIDIHETGIVEEFVTEIQVPITK"
     gene            1011..1250
                     /locus_tag="PC465_001597"
     CDS             1011..1250
                     /locus_tag="PC465_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648914.1"
                     /translation="MKCSNCGSVNIEKGILTTGGIYAETIGLKYRGDGKLDKVINKTF
                     PVQSTIYSDLCLDCGEIVRTYIKDNTDRNWCKDKK"
     gene            complement(1437..1613)
                     /locus_tag="PC465_001598"
     CDS             complement(1437..1613)
                     /locus_tag="PC465_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648915.1"
                     /translation="MFRDEMDKCTHMLTAYISSLYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(1667..1763)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(2118..2792)
                     /locus_tag="PC465_001599"
     CDS             complement(2118..2792)
                     /locus_tag="PC465_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDF2648916.1"
                     /translation="MNHHILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIV
                     ALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLT
                     TAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISN
                     STDSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPL
                     IETLEI"
     gene            complement(3012..3566)
                     /locus_tag="PC465_001600"
     CDS             complement(3012..3566)
                     /locus_tag="PC465_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDF2648917.1"
                     /translation="MSIALILIDIQNDYFKNGKCELFQSEETAENAKKILLFFRKNNL
                     PVIHIQHISTDKTASFFLPNTHGSEINKIVFPLDNEEIIIKHTPDSFFETDLQSILEK
                     KNITNLVICGMMSHMCIDTSVRTAKKLRYDITLISDACTTKNLSWNNIEINANTVHQV
                     FMASLQNSFADVKNTDKFLSNYHK"
     gene            complement(3644..4009)
                     /locus_tag="PC465_001601"
     CDS             complement(3644..4009)
                     /locus_tag="PC465_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2648918.1"
                     /translation="MKIRAEYTCPLEIVHDIIKGKWKTILIFELRQSNKTFSELQHNI
                     YGINQKMLIQQLKELRDFGIIDKISSAGYPLHVEYFLTNRGKKMLKAVEIMQEIGIEY
                     MLEHGQQEILDNKGICYNK"
     gene            4474..5259
                     /locus_tag="PC465_001602"
     CDS             4474..5259
                     /locus_tag="PC465_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2648919.1"
                     /translation="MIVKIDNTLEKEFWQYVSHEESLNLFIIGYVENYGFSSQYQDIW
                     SQVEDGNITSIILKNKSTLIIYSFKNNFNIGEMKNHIKDLDVESISGKKCVIDRLISK
                     YKDFYEKLDNKFCVLKEIKEIDFSNMKEYKIENAQEKDIDEIGKLLNRSDYKVSKNYI
                     EERKEHLKEGNVRAYFIRNDDTMISTVSTGMETSFLAMVVSVSTDKRYRGKGLASYMV
                     YNLSKELLLEGKVPCLFYNNDVAGKIYHNIGYKEINEWTILFK"
     gene            complement(5356..6180)
                     /gene="pdaA"
                     /locus_tag="PC465_001603"
     CDS             complement(5356..6180)
                     /gene="pdaA"
                     /locus_tag="PC465_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HDF2648920.1"
                     /translation="MKKDSLKKYIMIGAFALVLFGIASINFKSLDKTKTQISSPTLDT
                     HEYDWYFNPREDGKQPSPIKEADFFKKYGAYYVGNPNEKVIYLSFDAGYESGNTPKLL
                     DTLKKHNAKAQFFVVESYIKSNPELIKRMEKEGHLVCNHSKSHPSMAGITDFEKFKEE
                     ITSVEKAYKDVTGKEMPKYFRPPMGKFSEQSLKYTQDLGYKSIFWSFAYVDWYEKKQP
                     THEFAKNKIYSRTHPGAIVLLHPNSSTNTEILDEVLTHWEKEGYKLKTLDYLNNKK"
     gene            6401..9520
                     /locus_tag="PC465_001604"
     CDS             6401..9520
                     /locus_tag="PC465_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDF2648921.1"
                     /translation="MDNIISVLNDVVFLDIEVSGLDCLNSEILEVGAVKVKDWKIHTY
                     ESLIKNKFEVPIEVFSVCKNLDKNDLEIANEIELVEDRLVNFVEDSFIICHDLSLKKK
                     FFEYHMPKLKNKFIDLIELAVILEPYHKDYSLEYLKNTLTNCNSKVENRALSDAIDII
                     NIVNCLLVKFNNYEKTTLEPLSFKINSYLKKFNLPTWEWSKFLEEANYDLSNNINIKK
                     EYNIFDSKEEKKKERETLKILNEEEKNYEELLKYKTIWENKEGFTYEYRPGQYELTKT
                     IRELFRNSEDEEKIACIEAPTGIGKSVGYLLPAILEARINKKRLLISTDTKELQIQLI
                     NKDIPNVLDSLGLNGKVSYGYIKGKNNYICIDRLEAYIDDYESQNPTKGEILSLIFLK
                     RLVEGGKYGDIEEINYLVFDNFKEISTHLRNVSCDPNMCRPKKCKKDCLYKNRIEELK
                     EEHITVVNHSLLAKWPYKDEKPLENIIVDEAHNLTEKGYDFFSSIINSKSLRYLLQEI
                     YPYEFIQNSSFIYKKYSRNMRKIKAFDKFYNVLKIGREDKQKIARSINLIIEEIDSIL
                     NFGNCNEYNNVSNYNLRWELNLQIDEIVGKLKKGGIDTEISYRAYSEKIKLSCEKIIK
                     NLVSIIIIIYRNIDDDSIDKEADIYKFGKAKTRDLEDIKIIFEIFLEYDEKDDYARIV
                     EIDKNYNDFEFRVVPLKIADLFEENILSQLEKGIFLSATLSLSESMSYFKNTLGIDRV
                     KNVEKIIEPIFDYKNRVSVVGFSDICEYRNSEFPNEMSKIISNISKITEGHTLALFNS
                     KDRQEKTYEILKKYLHSFNLEIYADKKGIRHLNDLNRKCVVLGSKGCFEGVDIPGDGL
                     VCVTLDKLPNLNPKDPLYFTIMKKYGIDYYTINYPQMTIKVKQAMGRILRSKYDYGCF
                     VIFDVGTNISVLKRLEKDLHDCKISKVNSNEFYTYIRRHLNKSRSLILKSVIFDTIKA
                     LNVDAKMDNNDVDKDIIKKDINENIRQRAVKGEVYHIDIIKKDMKVKYFDRNYLINLD
                     IFMREEDKN"
     gene            9538..10137
                     /locus_tag="PC465_001605"
     CDS             9538..10137
                     /locus_tag="PC465_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H family protein"
                     /protein_id="HDF2648922.1"
                     /translation="MAKQKFYAVKKGKNIGVYNTWDECKKQVNGFSGAEYKSFSTFQE
                     AKEYIDGSEKLSFQEDKEFIEAYVDGSYEHSVKMYGSGVVILKNNEVIKTYSEKGKEK
                     TLVSMRNVAGEIEASKIAMQYCIDNNVQNLILYFDYEGIEKWCTGVWKTNKEGTIAYK
                     NFYDSIKNKLNVKFTKVKAHSGNKYNEEADKLAKKAIGV"
     gene            complement(10379..12508)
                     /locus_tag="PC465_001606"
     CDS             complement(10379..12508)
                     /locus_tag="PC465_001606"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HDF2648923.1"
                     /translation="MPNLPSLGSKAPDFKANTTNGPIRLSDYKGNWIVLFSHPGDFTP
                     VCTTEFLCFAKYYDEFKKRNTELIGLSVDSNSSHLAWMYNISLLTGVEIPFPIIEDRD
                     MRIAKLYGMISKPMSDTSTVRSVFIIDNNQILRTILYYPLTTGRNIPEILRIVDALQT
                     SDRDNIVTPANWFPGMPVILPYPKNYKELKNRVNSCNKKYSCMDWYLCFVPDNYNDEE
                     VSKKIDNTCSWKKEHTKNIENECNCEHEHHDYLNKALDCKQEHKTDIKDDCNHEKKHT
                     KNTNKVHNSKQDKFKDKSCDEMNFNYDKDESCDKINSSYDKEDSSYEDFYKHNYKNYD
                     YTSEKNTKKIAMKTLKDSKKLVRPQITDPYNPIVENANCPDINPIVAEYVLGNPTNVD
                     AQLLDAVIFAFAEIDQSGNLFIPYPRFLNQLLALKGEKPSLKVIVAIGGWGAEGFSDA
                     ALTPTSRYNFARQVNQMINEYALDGIDIDWEYPGSSASGITSRPQDRENFTLLLTAIR
                     DVIGDDKWLSVAGTGDRGYINSSAEIDKIAPIIDYFNLMSYDFTAGETGPNGRKHQAN
                     LFDSDLSLPGYSVDAMVRNLENAGMPSEKILLGIPFYGRLGATITRTYDELRRDYINK
                     NGYEYRFDNTAQVPYLVKDGDFAMSYDDALSIFLKTQYVLRNCLGGVFSWTSTYDQAN
                     ILARTMSIGINDPEVLKEELEGIYGQF"
     gene            12774..13022
                     /locus_tag="PC465_001607"
     CDS             12774..13022
                     /locus_tag="PC465_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648924.1"
                     /translation="MMICFAMTFALVLINSVMGVHIGLDYYFLMGSVLTVCLTIGIVL
                     CNARKIFDSKAIHKTRTKTVSNNKKQKSHSRDIKRKIS"
     gene            13188..14579
                     /locus_tag="PC465_001608"
     CDS             13188..14579
                     /locus_tag="PC465_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HDF2648925.1"
                     /translation="MNFRDLFEKAVDFIDEKRKSIVAISLSTLGVIALIIVFFLSSNE
                     FSVGNEANELLKIIEKRQYSIAVDYYTSIEKKFSDSKMERFNKSVSKKINKLLLNSGD
                     KYLDGDISQESFIGLINTVKELNKISIDVDDLLAQADRVREMYKEENTTYDIAINYIS
                     TVSILNGMGSNLDVYKQNIETIKESRDVYDSAVKDQKAYKYYEAIEKYNKVLKEDEKY
                     YSMAQNGKEQCIEEMYDYYISRAEEANTSGDYERALQYIEYLKDDYSDDEKVQSLEKK
                     YKKNLSLYTLTSDDIINVIAKKSGKDKANLSINSLPQMIKNNKYYYAEVYEYDKLINE
                     VLVSAKTKDLYSYKDGKKDYKVDYGDGYFRILEDGSYQFGITKDKAKFVLTNTLDEKE
                     NKYKKIEILDIEKADRYVKSKKSLEELFGKYKNIYYYAVVNKGLFRGKEVYAINIYNE
                     KIYAISENGLNEY"
     gene            14690..16159
                     /locus_tag="PC465_001609"
     CDS             14690..16159
                     /locus_tag="PC465_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HDF2648926.1"
                     /translation="MSNVNKKLVIAIGAVALVVIIFIGIMCMQFKGEKIAKNTYVNGV
                     NIGKLTKSQAKQELAKKYKLENVDFNYNDKSWKVKSKDLNLSTDLDKTVENAYNLNRK
                     SAFFGNLSKTISANFGKKSNLVVVINYDKNKLKAEMEKIAKEIDVDVKDATLDISGEK
                     VKVIPDSDGLKMDISKSMENFDNQTKKGNYKNELVVKATPAKVKKEQLANIDTNLGTY
                     STTFKTSQINRSINIKLATDNISNVLLMPGETFSFNKHTGKRSKENGYKSAPVIMEGE
                     MEEDYGGGVCQVSSTLYNSVLYAGLEIVNVKNHTIPSSYVPKGRDATVADSGIDFLFK
                     NNLKHPVYIKNYVSGNQIVCNIYGSAEDKQNITISTKLDGVSQTTMKRVNDPTMPKGK
                     EKVDKSGRNAYSVSTYRTFNDANGKKIKTEKIANSYYPKKEGIILVGTMEPKPEEKPN
                     TDENKNNQNTNNQNPNNQQKPETPPTDNKPNETQPQPQA"
     gene            16224..16817
                     /locus_tag="PC465_001610"
     CDS             16224..16817
                     /locus_tag="PC465_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HDF2648927.1"
                     /translation="MNLNNITNYVQSICENISNVLDVDVTLVTKDLTRIAGTGIFRGK
                     IGETISEKSVYSLVLKDGKSYVINKEIEENCNKCANRENCKELADICTPVKMGEHILG
                     ILGIAAFNEEQKEKILSKDKELTAFVRSMSDLISFKLDELYKQEVKTIDDLEREAIEN
                     AIKKYGSNTEGMKKVAEALNIGIATLYRKVKKFNIKS"
     gene            16999..18345
                     /locus_tag="PC465_001611"
     CDS             16999..18345
                     /locus_tag="PC465_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2648928.1"
                     /translation="MPRKILDISLIEDNKSDLTFFNIEEEDGDETLKALKQSYVTTNY
                     KEETLLNLQGALNSKSDTTSKELKLESYKRYNNALDLAYKNYITSAINMVNKALEINP
                     KDIDILNLRGLLKLLKCDFAKSFESFYTALCYENNHISRKYVNLISSEDFKTFLGRYN
                     HSIRFINEELNYESIHILENIIEEEPELIEPYVILSLLYDKLGNVKKREGYLDKLKEL
                     DKDNPVFEKNEEEKEDTSKKEEIKKVKRKKSILPYIIVGCVLIGMGIYLIQSKKRIEN
                     LNNQISSKEEKLSETDKKLGETSKKLEKTNKELNEVKNKEPEREITVADEEDLYYQAL
                     NLKKNKEYEKAIDNFKSVVSSGKTKKYISESIYQLAITNKLLGNKDEAIKYYKKYINT
                     YTKNDQYYDDSYYELGMLYYDNGDLKNAQQTFYSLRSEVPDSMYNNSKIKEILSEK"
     gene            18527..18898
                     /locus_tag="PC465_001612"
     CDS             18527..18898
                     /locus_tag="PC465_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HDF2648929.1"
                     /translation="MKVFNQLVIILSIWVIGEYISSFIQGIILIPGSIVGMLLLFLLL
                     QFKVLDLSSIENVSGFFLDNMAIFFIPAGVSLIKSLDLIRENVLVLLLVICLSTLIVM
                     YTTGIIVEKMIKKKEEGQKNV"
     gene            18891..19580
                     /locus_tag="PC465_001613"
     CDS             18891..19580
                     /locus_tag="PC465_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HDF2648930.1"
                     /translation="MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGI
                     ILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIVGIGCGI
                     VISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGIESITVVAIIFTGIF
                     GGMVASTVFKLGNINHPVAKGIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTIT
                     VILIPIIMNFI"
     gene            20100..20966
                     /locus_tag="PC465_001614"
     CDS             20100..20966
                     /locus_tag="PC465_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2648931.1"
                     /translation="MSEVKNTLQKHPVLRYSTMLFGMLMTSIGINGFLRPAHLLSGGA
                     TGIATSINYLTNINVGLLTFLINIPIFILGFIYLEKEFCISSLVNMIVFSLLLGATQE
                     ISNIIPIHDILLQSVYGGILSGLGVGVVFRTRSSQGGTDIIAAILKIKKNIEMKDTAL
                     AINGLIVLTGSFLFGLDLALYTLIGLFLNAYSMSFIKDAMNYQKSVMVMSNEVDLIAE
                     DIMKSLVRGVTFLDAEGAYTHQKKKIIYTIVSSNEIPKIKDIALKYDKKAFISVNDVT
                     EVKGRGFKAKDL"
     gene            21208..22017
                     /locus_tag="PC465_001615"
     CDS             21208..22017
                     /locus_tag="PC465_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648932.1"
                     /translation="MNLSKEYVNLYDNYLKYINEVNKEIRSIKNMKKRVLKRGDFAPE
                     NEVLELEGKTIRDIDDVDTKKPKNKIYKFSNGDVYVGKFLEGKMEGKGSYTFFVDEGT
                     VMEYIGEFKEDKKNGKGNFIFSNGNEYIGYFEEDMMSGIGNMLYSSKDEYIGTWKNGK
                     KDGKGIYKWSDGCIYAGEFKGGKMEGYGICYNSKGEVLYEGEWKNNLIHGKGTYIWEK
                     GKKYIGEFMHGKKHGQGTFYLNNELVYEGTWKFDKPSIFDRTLDEIFSLRL"
     gene            22161..23225
                     /locus_tag="PC465_001616"
     CDS             22161..23225
                     /locus_tag="PC465_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HDF2648933.1"
                     /translation="MKRLIALVLVVLIVLFYSPELLKEGYDLKEKFFQSEIWNEFLDK
                     ININDNSKKDKKEKSQNLQSNNTEGENLGESDIKNFEKISLGDNLSYVLSSIGKPGRI
                     DISEYGFDWYVYNQYGKEFAMVGLENDEVVALYSNSINSCENQDIKLNQDRQTVRTKI
                     TPLKYKRKGNTRYIINSENQYDIISKEGKYITIFYDIHEENRVCSYLIIDKSTEDEFK
                     NLYPDDSEELKKCFELEVIDLVNSVRNQRGLNSLRYSEQATLSSIKHSEDMRDNNFFD
                     HVNKKNETPFDRMKREGIVYTSAGENIAAGQINAIYAHEAWMNSEGHRKNILGNYNNI
                     GVGVIFGGSYKTYYTQNFYK"
     gene            23253..23972
                     /locus_tag="PC465_001617"
     CDS             23253..23972
                     /locus_tag="PC465_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2648934.1"
                     /translation="MTSWKKKTVYKCLIAVVLFCGIVLISNFSKVSALMMDTNGNVLI
                     KHGSREKKLIAITFDDGPHPKETSQVLDVLKKYNVKATFFIAGKHAKWYKEPLVRASK
                     EGHEIGNHTFNHPDISNLSSSQIEEEIVKCEDILKEVTGKKPTLFRPPFGSYREKELI
                     EIAKKHDYKVVLWTGVDVKDWKNPGANSIADKIINKVQNGDIILLHDYATNDTVEALD
                     MFIPKMIEKGFKFVTVSELIK"
     gene            23996..24580
                     /locus_tag="PC465_001618"
     CDS             23996..24580
                     /locus_tag="PC465_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HDF2648935.1"
                     /translation="MILMIDNYDSFVYNLVQYIEELGETVVVKRNNEIKISDIEELNP
                     EVIVLSPGPCSPKEAGICIDIVEHFKGKKPILGICLGHQTIGHVFGGDIIKAQQPVHG
                     KVYSINHTNKGVFRGLKNPLNVTRYHSLIVDSNTVPKELEITAITDKGEIMGIRHKKY
                     LIEGVQFHPEAILSEYGHEMLKNFITEARERVHM"
     gene            24582..25931
                     /gene="pabB"
                     /locus_tag="PC465_001619"
     CDS             24582..25931
                     /gene="pabB"
                     /locus_tag="PC465_001619"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HDF2648936.1"
                     /translation="MIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISS
                     QPFKVLKYKDTDENPLEVLKEELHKYRVVNDTNLPFVGGAVGYLSYDLGNYIENLPRT
                     AVDDIEMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIELEEKIIDDIEQRILKEEKKG
                     IDSICYEEKEVTSIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTS
                     FELYRDLRRFSPAPFGAFLNFEDAHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKE
                     EDLRLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVS
                     TVVGELKDDKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFN
                     GDMDFNIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE"
     gene            25921..26664
                     /locus_tag="PC465_001620"
     CDS             25921..26664
                     /locus_tag="PC465_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV family protein"
                     /protein_id="HDF2648937.1"
                     /translation="MKNNVGFDSSLSKFGIGLFETIRVKNGIAVDLDIHIERMLSSIN
                     CLDLDINYTKDFLINEIVTYIKKENVINKALRITVFDEGYNISIRDVPYNQETYEKGF
                     KLAISPIVRGNSLIHRHKTTNYFENIYTKNIANKTGYNDGIFLNSEGVILECSMSNIF
                     FIKGERVYTPSDRLPILNGIIKKRIIEICDELHIELIENEINISEISSFDFVFVTNSL
                     MGAIKVTEIDKIKFNKENVVFDKIVKLLE"
     gene            26698..27399
                     /locus_tag="PC465_001621"
     CDS             26698..27399
                     /locus_tag="PC465_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648938.1"
                     /translation="MIGCIYEVYNEEITKIIENQNTLAVYLVGSSKDVDFTLYDVEIN
                     DIDVFVFVKEGEKQERILFKKKGIEFDVNYFSKDGVKKLLSNREYFFVKEMKDAKVLF
                     DRENISHIIKDISRNIYLEGPSKMSLEEKSFIKQDIGAKISNLKNKEKFDVFEYHFLT
                     NLYLKDIIIGYFNINDKWVPKDKKLLKVLKKENNELFELVSKVSENYDYQRLLDVYNY
                     IFKEIETKEVIKLIF"
     gene            27425..27997
                     /gene="folE"
                     /locus_tag="PC465_001622"
     CDS             27425..27997
                     /gene="folE"
                     /locus_tag="PC465_001622"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HDF2648939.1"
                     /translation="MNKVDKEKIQHAVREILEAIGEDPDREGLIETPNRVARMYEEIF
                     SGLSEEPRDHLKVLFADEKHEELVLVKDIPFYSCCEHHLVPFFGKAHIAYLPKGGRLT
                     GLSKLARVIDTLAKRPQLQERITKNAADIIMEELQPYGVLVVVEAEHMCMTMRGVKKP
                     GSKTVTSAVRGIFEKDIASRAEAMSLITMK"
     gene            28061..28852
                     /gene="folP"
                     /locus_tag="PC465_001623"
     CDS             28061..28852
                     /gene="folP"
                     /locus_tag="PC465_001623"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HDF2648940.1"
                     /translation="MFDYGKRTYIMGILNVTPDSFSDGGDFNNLDIAIQHAKDMVDQG
                     ADIIDLGGESTRPGHSYVDSDEELRRVIPVIKKLKQELDIPISIDTYKADVAEEALKL
                     GVTMVNDVWGLRKDKNMASVIGKYDAEVCIMHNQDGTNYDKDIMESIKDFFKVSIEMA
                     MSYGVKKEKIVLDPGVGFGKDFEQNIEVLRRLNELKDLGYPILLGTSRKSVIGKVLPV
                     EPKKRLEGTIATTVLGIRDGVDIVRVHDVYENLMAARMTDAIYRK"
     gene            28863..29228
                     /gene="folB"
                     /locus_tag="PC465_001624"
     CDS             28863..29228
                     /gene="folB"
                     /locus_tag="PC465_001624"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HDF2648941.1"
                     /translation="MDKILLSNLGFYGYHGVLKEENFLGQKFFVDMELYIDSREAGLS
                     DDINKSVSYAEVYNVVKDITENKQFNLLEALAENIAEEVLNKFILINGVRVRVRKPEA
                     PVNGIYDYFGVEIRRARDE"
     gene            29221..29727
                     /gene="folK"
                     /locus_tag="PC465_001625"
     CDS             29221..29727
                     /gene="folK"
                     /locus_tag="PC465_001625"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HDF2648942.1"
                     /translation="MNKAYLGIGTNMGDRFDNLSRACELLKNSDSIYKVKESSLYETK
                     PWGYTEQADFLNMCVEIETEFEPYELLEYCQEIERELHRERIVHWGPRTIDVDVLFFN
                     DVVSTDERLTIPHPRIQDRAFVLIPLMDLNEKLIINEKTIKEHLNLLSAEEREEVKEL
                     VGYERKPI"
     gene            29708..30493
                     /gene="aroF"
                     /locus_tag="PC465_001626"
     CDS             29708..30493
                     /gene="aroF"
                     /locus_tag="PC465_001626"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HDF2648943.1"
                     /translation="MKENLFNNNSKIEINTNNKKITVKKDKLIIAGPCAIESYEQLLE
                     TAKFVKSQGANILRGGAYKPRTSPNSFQGLKKEGLEILKAVKDEVGMAVITELMDVRD
                     MDELYSISDIIQIGSRNMQNFTLLSEVGKQNKPVMLKRGIASTITEWIGASEYIAIEG
                     NSNIIMCERGIRTYNDYTRNTLDLAAVPIIQKETGLPVVVDPSHATGVRYLVKPMSLA
                     SFACGADGIMVEVHPDPENALSDGAQSLCFNEFEDLMKSINNY"
     gene            30748..32538
                     /locus_tag="PC465_001627"
     CDS             30748..32538
                     /locus_tag="PC465_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDF2648944.1"
                     /translation="MNDIKDIIEEIKARCDIASIISEYMNIKQSGANYKGLCPFHGEK
                     TPSFYINTSKQIYKCFGCGEGGDVINFVMKMENLDFMDAVKILANKCGIEINTNMNEE
                     TRIKIEKSKKFQDIHTEAARFYLSNLLGSKNLGYEYLRIRGLDDKIIKKFGLGFSLDS
                     WNSLMNTLISKGYKKQDLLECGLIAKNRDGTNCYDKFRNRVMFPIFDYRGNIIGFGGR
                     VLDDSLPKYLNSPDTLIFNKKQNLYGLNFARKNLESKTIVLVEGYMDLISLYQYGIKN
                     VVATLGTALTEQQGILIKRYADTAIISYDSDEAGIKATLRAIDILTKLGINVKVLDLK
                     DAKDPDEFVRKYGLSDYKKAMDVSTHYIKYKIDHLKKEFNIQKDEERVKFAKEASKII
                     KQLTSPVEIDFYTKYLSNQIDINVESIKREVYGKNYNKPYNNKNQKKIEEKVIEKVEV
                     RQDGKQLVEETLIKIMLEDKKIREIALLKVEESDFLLKESKEILNYMIKNQELDKITI
                     DKLKSLNISEEYLKELNSISLNSINLENTKEIEGIITNIRKNSLEEQINSLLREQQEL
                     ENNNDMKEVDGRVMEIALKIVEINKILKSL"
     gene            32556..33722
                     /gene="rpoD"
                     /locus_tag="PC465_001628"
     CDS             32556..33722
                     /gene="rpoD"
                     /locus_tag="PC465_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HDF2648945.1"
                     /translation="MENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDK
                     DQVENLYETLGNLGIEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHDDSSAIEI
                     ETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANL
                     RLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRA
                     IADQARTIRIPVHMVETINKLIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKI
                     AQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKV
                     LKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD"
     gene            33887..34576
                     /locus_tag="PC465_001629"
     CDS             33887..34576
                     /locus_tag="PC465_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDF2648946.1"
                     /translation="MKLTDRLLKIASLASDGKKIADIGTDHGYIPVYLLKEGKVPFAV
                     LADVNKGPLDNAHKEVIQNNLLDKVDLRLGSGIEILEIGEVEEVIIAGMGGILISELL
                     EAKKEVAHNVEKLILQPMQAQEELRYYLLNNGYEILEEVLVREDFRIYEIIVAKYTGK
                     NTIIEDEIYYEVGIKLLENKDSLFNDFIEKKIKTYSSIVNKLEGKNGEAIDKKRKESE
                     VAIKKLENLIK"
     gene            34590..35687
                     /locus_tag="PC465_001630"
     CDS             34590..35687
                     /locus_tag="PC465_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HDF2648947.1"
                     /translation="MLLKSLTRKIEKKYPLNLAEDWDNVGLIVGDFDMDVKKVLVSLE
                     ANEDVIDEAISKNIDLIVTHHPFIFGKINKINSGDLKGRLIQKLIKNDISLYSMHTNF
                     DIAFDGLNDYFMEIMEFGNSKVLDITKSENLYKLAVYVPHNYSDELRKVLSNSGAGHI
                     GNYSDCTFSTEGEGQFKPLEGSNPFLGSVNDIETVNEVKIETVVPQKLLGGVISSMLD
                     AHPYEEVAYDLYKLENKGEIFGLGRISKLDKSMTLESLSRKIKEKLNMKHIRVVGNLS
                     TDITKVAVVTGAGSEFVKKAKRQGAEVLITGDVKYHEAQDALDIGMCIVDCGHFDTED
                     IFKNVMKRFLDEFSEIEVIKSNVYLNPFSTI"
     gene            35750..36322
                     /locus_tag="PC465_001631"
     CDS             35750..36322
                     /locus_tag="PC465_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDF2648948.1"
                     /translation="MKVAVIFHSVCGSTYLLAREYKEALEEMNIEVDIFRVSDEVAKT
                     LPQYYLINSKEYKDEFESINVIKSGKEILDYDAIFMGSPTYYGNVSGPMKMFMDSFSD
                     IWVGAPLSGKIFGCFATAGSQHGGGELALQAMNIFAQHMGMTLLSVPCSVRGGYPAYG
                     ILHIAGDNSDIRPNDDAKMGIRDYLKRLNI"
     gene            complement(36382..36849)
                     /locus_tag="PC465_001632"
     CDS             complement(36382..36849)
                     /locus_tag="PC465_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HDF2648949.1"
                     /translation="MFKEMRLKKREMTKEDTVEVLKNGEFGTFSTISENGYPYGVAVN
                     YVYFNDSIYFHCARNGHKLDNISKNNKVSFLVVANESVIPDKFSTTYSSAIVFGKACT
                     VENEEKKNALVEIIKKYSKGFFEEGMKYIEKDMNLTTVVKIEIDHISGKASRL"
     gene            complement(37235..37711)
                     /locus_tag="PC465_001633"
     CDS             complement(37235..37711)
                     /locus_tag="PC465_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDF2648950.1"
                     /translation="MLSKAEIKYFNECASEILSSEKVQLMRTFPHHGNVSCLEHSLSV
                     AYYSYLLCKKLHLSVDIQSVIRGALLHDFFLYDWHYKGDRKGLHGFTHPREALKNATL
                     FFQINEKETDIILKHMWPLTVKPPRYKEAFIVCLLDKFCCLVETLKIHSLLSPYHV"
     gene            complement(37831..38922)
                     /locus_tag="PC465_001634"
     CDS             complement(37831..38922)
                     /locus_tag="PC465_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HDF2648951.1"
                     /translation="MSKIECLFTIFPVLILMYATFYFMPYFVGKKHIYGVSIDQEHKN
                     YNYFIKLDKKFKKLLSLGFIIDFILVFILVFTFNKLELSYFIGIIGFLLYESILYIHT
                     HKKAKKLKLEIYAKLGHIDIDSKLIVDMDFINKKNKIIKKFKIIYLIPILFTLGMSIF
                     IAFNYNQLPDSIATHWNINGSPDVFIDKSFLNVFKLIGTDFCLMVLLYITSIGSIKSR
                     IKIDTNRIEESRVENIKYLNKIGYLFLILMIIMTTQFFTTLLSIKTKLSTAMNITTLL
                     VIIYLIATYINSPNLKFNSSYSPEEDEKYWIAGIMYNNPNDPSLMVNKRFGIGWTINF
                     GNPLGKILYIAIALLLIFSLFSLIKSLLL"
     gene            complement(38915..39304)
                     /locus_tag="PC465_001635"
     CDS             complement(38915..39304)
                     /locus_tag="PC465_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2648952.1"
                     /translation="MVLNLDFNSDKSIYVQIKEEITKAIASGELKINESLPSVRSMAE
                     NIGVNLHTVNKSYNELKEEGFLNIDRRKGAIVAQLPMKIDNTTRQKNKLDLELLVAKS
                     YLSGISKEEFLSLSSSLFDKYEVKYYE"
     gene            39496..39942
                     /locus_tag="PC465_001636"
     CDS             39496..39942
                     /locus_tag="PC465_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2648953.1"
                     /translation="MLTYLMKRQMHKKDDGMSKPMMITGAVITGVGAYAVYKMVKSHK
                     SNSQMVNTNYYGNSDYDDYKYDEFDYDCDCRDTKQDYEYEELKKKVKEFNSRRINCEN
                     CPHVSQEEMMQYVNSVKDVKEEIDLHEDAKKDNIYKEDEYKKYEEE"
     gene            40206..40931
                     /locus_tag="PC465_001637"
     CDS             40206..40931
                     /locus_tag="PC465_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2648954.1"
                     /translation="MKRKEIVMLKLLIVEDDSTISFGIKYALEQEGFSIDISKDLSSG
                     KEMISSNEYSMILLDVTLPDGTGYELCQYIRGFSQVPIIFLTACDEEVNIVMGLDIGG
                     DDYITKPFRIRELISRIKAVLRRKGNTSEENKKILKFGDLSIYTLEARVYKNDKEIFL
                     TSVEYKLLLILIQNKNTVLSRTQILEKLWDVTYDFVNDNTLTVYIKRLREKIGDDLCE
                     PIYIETVRGIGYKWIGSENSVSI"
     gene            40918..42162
                     /locus_tag="PC465_001638"
     CDS             40918..42162
                     /locus_tag="PC465_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2648955.1"
                     /translation="MFLYNPEVKKFLSKYVTLMFIVIIISIGFSIINVSLTKEMVVRN
                     NQAIIGTLSSKYPNLESQIVDIITQGKSMENIDYGQKILIKYNYDKSIRINSEPIISK
                     LVLETIKINIILVCIIFILIFVLVVRYFTSIYNDLSDMTKYVYYSSEGKPFDMKNKNQ
                     EGQIGLLKTELLKMTTILNEKVELLKREKIFLNNTISDISHQLKTPMTSLIMLNDLLY
                     NDVPYEVKIDFLNKIKNQLNRMDWLIKSMLKLSKVEAKVINFKKDKVKFSELIHRAML
                     SMKIPMEIKNQKLTIEGNDNVSYIGDIDWSVEALVNIIKNCVEHTPEFGNIIITYKEN
                     PLFSELIIKDEGEGIDKKDIPHVFKRFYRGRSSSKEDSVGIGLAMSKSIIESQNGDIY
                     VNSEKGKGTEFHIIFHKMYDSD"
     gene            42242..42919
                     /locus_tag="PC465_001639"
     CDS             42242..42919
                     /locus_tag="PC465_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2648956.1"
                     /translation="MEILRVENLTKSYGKNETKVDAIKNVSLSVEKGTFIAITGPSGS
                     GKSTLLHLLGGVDRPTSGKVYINDVDIYNLKTKDLAIFRRRNIGLIYQFYNLIPVLNV
                     KENILLPAELDNRDIDREYFDDLMKTLGLIDREKHLPNQLSGGQQQRTSIGRALINRP
                     SIILADEPTGNLDSKNSKEILELLKLSVKKYNQTLIMITHDKNMALQADRIISIEDGI
                     IKSDEVM"
     gene            42920..45481
                     /locus_tag="PC465_001640"
     CDS             42920..45481
                     /locus_tag="PC465_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2648957.1"
                     /translation="MNLYTSLTIRYLKQNKRRTIVTIIGIILSTALICGIGNIFESFM
                     DYQMRETIKNDGSFHVTFYDVNRKNVEYVTKSAEIEKHAFTKQLGYSKLENSENAILS
                     IKQYDKNAINGYKVSIKEGRFPAKEGEIVLSESIINLIDDKLKIGDKITLKVGDMFDS
                     SKKKIDSMTFHEGDYIANEKDRTFKVVGIIEKPGFERYNGIATAIAYFNPMNNYNDTI
                     NVSVAVRNPKDVYKISNKISKNIYSNKDKEAVSDMIKYNEHLLRLQGASKYSNINSSI
                     KSIIIAVTILVIICTIATVYNSFSISINERKKQFGILNSIGATSSQIKRLVFIEGIII
                     SLIGIPIGLISGTVAIDLLFKIINKYFTESVVTKMSLQIVYNPIIIIVSIIIVLLTIF
                     ISILLPAISASNISPLNVIKNTGEYKVGKIKSSRLIKMIFKTEGVLAYKNIRRNRKKF
                     IITLFSLMVSIIIFISFSGFTLLLLRGEEIRNSQRKYDLYLTAKNTARSVEDTISELE
                     DIDGIKNFELATGQYVSIRVSENKINKSKEDLIRKYYQKYKIGDSYEYDFSNNELIFP
                     GDFAVKNKINNLVQGSFNKERAIEENGVILVRKSAFEENGKKGVVELTNYKVGDTVNC
                     EYLDENALSKKVKVKILAITDEERLGLGYQNMGLQFITYDEVAKNLNLKLSKSLIFID
                     SGGSIKTKKEIEALANKNNFNFYDESASNESEKQDLKVIKIFVYGFIVVISLVSVTNI
                     LNTVSTSINLRKRELAVIQSIGVTPKGFRKMIYLESFIYGILSLLFGIPISIGIILIM
                     NKLISGVIEFSPIIPWTAIVICIVSVFIITFIAGYIPMSKLNKENIIDNIRRESI"
     gene            45702..46976
                     /locus_tag="PC465_001641"
     CDS             45702..46976
                     /locus_tag="PC465_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2648958.1"
                     /translation="MITISHITAKNMYKSLEERINKFPQGAPPSDTLYKILNVLYTEQ
                     EAKLVAQLPIKPFRVKTAAKIWSVSESEAYRVLDKLASKALILDIEDNKGKKYIMPPP
                     MAGFFEFAMMRTRHDIDQKLLAELYYQYMNVEEDFIKDLFYSTETKLGRVYVQEEVLT
                     NDNEVSILDYERATHIIDESTHIGISMCYCRHRMQHVGKACDAPMDICMTFDNVANSL
                     INNKFARRVDKIECKELLHQAYEHNLVQCGENVRKGVTFICNCCGCCCEAMVAAKRFG
                     NLHPVQTTSFIPNINHENCVKCGKCITACPIDAISKVKEDGKEYIKIDEDRCLGCGVC
                     VRNCHKNSIMLLKRDEKIITPANSVHRAVLMAIEKGQLQNLIFDNNALASHRAMGAIL
                     SAILKLEPAKKILASKQLKSVYLDKLLSINDK"
     gene            complement(47137..50178)
                     /locus_tag="PC465_001642"
     CDS             complement(47137..50178)
                     /locus_tag="PC465_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp20"
                     /protein_id="HDF2648959.1"
                     /translation="MFKQRLSKLLSSTLVLSMLFTAAPNITFADNTKDNSEKYQSSDI
                     ELHDYSKNAESYTKTKALAKEKIQTLLSKYGAVSAQYALIDNGKIEISGNGGVYSKQD
                     NKNLNKDNMYSIASISKMFTTTAVMKLVDDGKLNLDTPVVKYIPEFKMADDRYKEITP
                     RMLLNHSSGLMGSSFKNTILLADNDSYGHDNFLKELQKQRLKAKPGAFSVYCNDGFTL
                     AEILVERVSGMSFTNFLDKYINNPLNLQNTKTTENSFDSSKLAKAYVPYWEDAVPQDN
                     LNAIGAGGLYSSAENLCTFAQTFMKNSNGILSPASVKAMENKEYLNGLWPEGEDSILG
                     YGLGWDCVNTYPFNQYNLKALTKGGDSLLFHSNLIVLPDENMAVAVLSSGGSSQLNEI
                     IGQEILLSALKEKGKIKEIKPDKTFSKPQQVKMPSSLKENSGLYASSNMIKVDVNDNG
                     TLTVSSPYIENGPEDKYVYIGQDRFVSEKGNSCLKFVKEKNNITYLNMSSYDDVPGLG
                     QTASLYYVAQKVDDNNISNSVKEVWKKRSGKGYYLVDEKYTSQSYMFGSVKASFSLSD
                     ETPGYIVNTKIMDENNSNAFIEIPGVIGRDLSDIKLHKENGTEYLSFGTLTYVSEDSI
                     TNLPAEKSFTCELESNGYAKWYKIGDDIANKKIEVNLPQNSAFAVYDDKGVPVNYSLV
                     TKNNRVRLPKGGVIVFLGSPNARFEVTYQDEVNASALTGTDRYETSIKISQAGWENAE
                     NAVLINDSAIADALAATPFAYKKNAPILLTGSSQINEKTLAELKRLKVKNVYVVGGEA
                     SINEKSLDTIKSNNISVSRISGSDRYQTSMNIAKELNNISNISKISVVNGEKGLADAV
                     SIGAVSAQNDMPIILTNENSNITEINNVFKNKKIDKSYVIGGEYTVSKNIESKLQNPQ
                     RISGSTRNETNAKVIKEFYKDSKIDNLYVAKNGMNKQDDLIDGLSVGVLAGKTKSPVM
                     LVGNSLDYNQKELFKTMRFKSVTQIGGNGNENSFKQIKEIA"
     gene            50385..50684
                     /locus_tag="PC465_001643"
     CDS             50385..50684
                     /locus_tag="PC465_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDF2648960.1"
                     /translation="MYKNINKKQLKEMMKNEKDVLLLDVRTKDEFKEYKIENAINISL
                     QELINNIDEIYDYKDKKVVVYCRSGHRSVTACNLLAEEGFEHLYNLNSGIIDYMS"
     gene            complement(50922..53150)
                     /locus_tag="PC465_001644"
     CDS             complement(50922..53150)
                     /locus_tag="PC465_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HDF2648961.1"
                     /translation="MRHLKKTNSLKEILNWNNIKNLRPSKGLKNILEIFKSDLKDIRG
                     NYAVLVIVLGLAFLPSLYAWFNIKASWDPYGSTANMLVAVTNEDKGNEIAGQKINVGD
                     QLIEQLKDNKSLGWQFVDEKTALEGVKKGTYYASLKIPKNFTKDLTSLITDDVKKGEI
                     IYTVNEKINAVAPKITDKGASTIQLQVNQTIVKTVSEIVLGISNGVGAGIEHSLPKLT
                     KVENSLIDLQKRFDHINKTVDLASDATSKLSDTVKDIKSDLPTIKKTLNDTKLLSSDL
                     KKFLEDTNDNLDELSPLIKSDLNLMVDLSSSASSLTLNLIDAVNSGSEDVPKLIDNLS
                     EKLSNLQSLNNTLVDFLTKLNQLTSNNRLDDVIDNLEDSSNKIDSSISTLNDIKNKVI
                     SGQQPSISALNNVLSLSNGIGRINLNILNNFDSKISKPINSIFANSIKVANDIITVLD
                     KAEAKLPKVEEILTTSLKLSGNAQESISLIRERLPLAKGMLDDLIDTLSKISNGEDMK
                     KLVSLLESDILTKSNFLKEPVEVKTEKLYPIENYGSAMTPFYSVLSTWVGILLISALL
                     STSVHGNYKPYEIYFGRGLTFLSIALVQGFIIGTGDILLLGVTAKHPILLIVLLMFTS
                     MVFNFIVYSLVSVFGNVGKAIAIVLLVVQIGSSGGTFPIQVTPTFFQRINPIMPFTYA
                     IGATREAVGGIYAPNLTKDILVLLLFMILSICLNVLLKGPINRVIKPFNDKFGDSNLT
                     GH"
BASE COUNT        21169 a         5752 c         8736 g        17602 t
ORIGIN      
        1 gagtaataat gttgatttaa aataaaaata agatttcgga ggagtttatt atataaatga
       61 aagattacta taaaatagga gagatatcta aaatatatgg aataggtaga gattcattaa
      121 tgtattatga agaaataggc attctaagac cagttagaga tataaatgga tatagaatgt
      181 ataatatatc agatatatgg aaattaaatt taataaaaga atttagaagc ttgaactttc
      241 caatgaagaa aataaaagaa tacctagatg acagaagtat agagtctacg aaaaatattt
      301 taaatgaaga actcgattta attgataaaa aaatagctga atttataagc cataaggaaa
      361 atattataaa aagattgagt tcaattgaaa gtgtaattca aaatacaaaa atagatgaga
      421 tagaggttgt atatatagaa aaaagaaaag ctttagaatt aaatgctgat ataaagaggg
      481 atgaagactt cgatttttta attcaaaaac ttcagaaaga atatgaagat agatttaata
      541 tacttggaaa taacaatatt ggttctgcct tttctactga agcaattaat aaaggtatat
      601 ttaatgagtt taaatctgta ttttgttttc tggaaagtaa tgagaaagta tataatatag
      661 tttttgatga aggatattat gtaactttaa attatactgg gagtaattct aataataaga
      721 tgtatatgga gaaggtgttt aaatttatag aagaaaacaa ttataagata attgctgacc
      781 ctatagaaat ctacaagata gatatacatg agactggaat tgtagaggag tttgtaacgg
      841 aaattcaagt tcctataact aaatagctat atttcaatgg attagatggt aaatagaatg
      901 aaaaaatgtt gatttgccac cgatttgtca ctgtgttata aaatcggtag caaattatat
      961 tttaaattat aagatagcat gaaaaaataa ttgtttaggg ggttataaat gtgaaatgtt
     1021 ctaattgtgg aagtgtaaat attgaaaagg gaattttaac aactggtggc atatatgctg
     1081 aaactattgg attaaaatat agaggagatg gaaaattaga taaagttata aataaaactt
     1141 ttccagtaca atctactata tattcagatt tatgtttaga ttgtggagaa atagttagaa
     1201 cctatataaa ggataatact gataggaatt ggtgtaaaga taagaaatag aataattttt
     1261 gaagtatatt aatatttgaa gttgaatttt attaaagata caagtgaaaa agtataaatg
     1321 ggaagaaatt gttgtatgga agaaactttg catatagggg agattagttt tttaatataa
     1381 taacattttt aaatgtagat aaaactaaaa agggttctct agaaaacaat ttctatttaa
     1441 ttatacttac ttaccaatac catcacttga tgtaaacaag attctactac attttctccg
     1501 tactctagta taaaatcatc tagctgtgta tctataaaat cacaataatc atataaacta
     1561 ctaatataag cagttaacat gtgtgtacat ttatccattt catctctaaa catatatatt
     1621 actatccccc taaaaaactt tcataaaaca aaaagaacaa tatctttttg gcaactggct
     1681 gacataactc atagtttatt ttataagcgt tagtccctat agctttgcgt cactaaattt
     1741 ctctagtttt gccgatttag ttttattcta caactaaaat aatacactag gataagttat
     1801 tgttcaacat acttgtcaga aaattgaaat atttaacaat atcttaacaa tatgaaatct
     1861 atttttcact caagaaacaa actatatgta tagaatgttt aataaaaatt atatttagtt
     1921 ttgtattgaa gtttttatat taaaaagttt agttcacaag ggttacttgg ctagataata
     1981 gatgaacaaa aatatcttga aaaaatatat atgaatggca aaaaacaagg gatgaatttt
     2041 atatagactc atcccgtaat tatttatata ttgaccttga ttaaatatat tattattttt
     2101 aagcttcaat ttttatatta tatttctaaa gtttctataa gaggattatc gctaaataat
     2161 tttaataaat ttgttttttt atatccttta ggtaacttag tatatataac tacttctaac
     2221 caatccccat caaggcgttt aatattcatg tttataattt caatattaga ttttttaaat
     2281 ttaccttcaa tatattctat ggaatcagtg ctgttagaaa ttttaagaga aacttgctct
     2341 gctgtaggga gtttcatcca tttcctatct ctatgaagtg ttatctgtac aataacaata
     2401 atgatacttg aaacaatacc aactaagtat aatccagagc caatggcaag acctgtaccg
     2461 gctgttgccc atataccagc agctgtagta agaccactta ctgattgatt tctaataaat
     2521 attaatccag cacctaaaaa acctatacca ctgacaactt gtgctgcaac gcgggctggg
     2581 tctagaccaa tacctggagt acccactata tcattaaatc catacttgga aacaatgatt
     2641 ataagtgctg aagctaatgc cactataaaa tgagtgcgta ttccagcttc ttttagtcta
     2701 ttctttctct catatccaat taaagcccca cagaaaccag cagtaatgat tcttgctata
     2761 tattcaaatt gaatcaatat atgatggttc atttatctag cacccccttc tatataatat
     2821 tatatatact ataatactac attttttatg tgaatatagt aaagtttaaa atttatataa
     2881 tagttatata tgaatataaa atgtataaac gtatattatg tatataaaaa tgatagaaag
     2941 catctaattt taaatgatta aagagcaagc ttaaataaat caaacttgct cttttaacat
     3001 agtgtatgtt tttatttgtg atagttagat aaaaatttat ctgtgttttt tacatctgca
     3061 aaactgttct gtagtgatgc catgaatact tgatgtacag tatttgcatt aatttctata
     3121 ttattccaag ataaattctt cgttgtacat gcatcgctta ttagagttat gtcgtatcga
     3181 agtttctttg ctgttcttac acttgtatca atacacatat ggctcatcat tccacagatt
     3241 actagattag taatattttt tttctcaagg atactttgca aatctgtttc aaagaaacta
     3301 tctggtgtgt gtttaattat aatttcttca ttatctagtg gaaaaacaat tttatttatt
     3361 tctgaaccat gagtattagg aagaaaaaaa gaagctgttt tatctgttga tatatgctgt
     3421 atatgaataa ctggtaaatt gttttttcta aaaaacagta gtattttttt agcattttca
     3481 gcagtttctt ctgattgaaa taattcacat tttccatttt taaaataatc attttgaata
     3541 tcaatcaata ttaaagctat agacatgatt atacctccta tttattttta ttataatact
     3601 attgtaaaaa atgtaaatta cttacttttt ggtatgtata ggattactta ttgtagcaaa
     3661 ttcctttatt atctagaatt tcttgttgac catgttcaag catatattcg attcctattt
     3721 cttgcattat ttccactgct tttaacattt ttttaccacg attagtaaga aaatattcaa
     3781 catgtaatgg atatccagca gaacttattt tatcaataat cccaaaatca cgtaactctt
     3841 ttaattgttg aatcaacatt ttttgattta ttccataaat attatgttgc aattcagaaa
     3901 atgttttatt agattgtctt aattcaaata taaggatagt tttccatttt cctttgatta
     3961 tgtcatgtac aatttcaaga ggacatgtat attcagctct tattttcata gcatatcacc
     4021 cccagtaaaa tgataataaa ttatatcact tgtcttgtga tatgacaaat atatatgaac
     4081 tgtatataaa ttttatgttt tattaagttc taaatttctt ctattgtagt tcatatttag
     4141 tacataaata attagtaaga tataagtaaa taaatatata acatgactat agaaatttaa
     4201 ctttaaaata acttatgata atttagagga ggaatatata tgaatatatc aagaaaagct
     4261 atgaaaataa tagaattagc acaaaaaatt gcaaataaga gggggatttc agtagaagaa
     4321 gcttggagtg aagcagtaac agaatataaa aataaatacg aacatattgc atagatattt
     4381 aaaaatttag aatatttggt agaatataat gattttaaat gatactataa attataaggt
     4441 atatcattat taacatagaa ggaggatatc tgcttgattg taaaaataga taatacttta
     4501 gaaaaagaat tttggcaata tgtatcacat gaagaaagtc taaatttatt cataattgga
     4561 tacgttgaga attatggatt tagctctcaa tatcaagata tatggtctca ggtagaagat
     4621 ggaaatataa cctctataat attaaaaaat aagtcaacac ttataattta tagttttaaa
     4681 aataatttta atataggaga aatgaagaat catataaaag atttagatgt agaaagcata
     4741 agtggaaaaa aatgtgtaat agatagacta ataagtaaat acaaagattt ttatgaaaaa
     4801 ctagataata aattttgtgt attaaaagaa ataaaagaaa tagatttttc caacatgaag
     4861 gagtataaaa tagaaaatgc tcaggaaaaa gatattgatg aaataggaaa acttttaaat
     4921 aggtcagact ataaagtaag taaaaattac atagaagaaa ggaaagaaca tttaaaagag
     4981 ggaaatgtaa gagcatattt tattagaaat gatgatacta tgattagcac tgtgtcaact
     5041 ggtatggaaa ctagtttttt ggcaatggtg gtctctgtaa gtacagataa aagatatagg
     5101 ggaaaaggac ttgcaagtta tatggtttac aatttgagta aagaattatt gttggaagga
     5161 aaagttccat gtctttttta taataatgat gtagcaggta aaatatatca taatatagga
     5221 tacaaagaga taaatgaatg gacaattctt tttaaatagc tataaaaaat aaaaaactct
     5281 atcgagaatt aaagtattta taaataacta tatttttact ataattcatg atagagtttt
     5341 tttaaattta tgatactatt ttttattatt taaataatca agtgttttaa gtttataacc
     5401 ttctttttcc caatgtgtaa gaacctcatc taatatctca gtatttgttg atgaatttgg
     5461 atgcagtaaa actattgcac caggatgagt tcttgaataa attttgtttt tggcaaattc
     5521 atgagtaggt tgtttctttt cataccaatc tacataagca aaactccaaa atattgattt
     5581 atatcctaaa tcttgtgtat attttaaaga ttgttcgcta aatttaccca ttggaggtct
     5641 aaaatactta ggcatttctt ttccagtaac atctttgtat gctttttcta cacttgtaat
     5701 ttcttctttg aatttttcaa aatctgtaat acctgccatt gatggatggc tttttgaatg
     5761 attacaaact aaatgtcctt ctttttccat acgctttatt aactctggat tgctttttat
     5821 ataactttca actacgaaaa attgagcttt agcattgtgt tttttaagcg tatctaataa
     5881 ttttggagtg tttccacttt catatccagc atcaaatgat agatatataa ctttttcatt
     5941 gggatttcct acataataag ctccgtattt tttaaaaaaa tcagcttctt ttataggtga
     6001 tggctgttta ccatcctccc tagggttaaa ataccaatca tattcatgtg tgtcgagtgt
     6061 tggactagaa atttgagttt ttgttttatc taatgattta aaatttatac tagcaattcc
     6121 aaaaagtact agagcaaatg ctcctatcat aatgtatttt tttaggctat cttttttcac
     6181 aatttcacct cttatttaaa atttaaaata tatttcttat aatatagttt gaatatttat
     6241 agttaaaaat attcacatat acaaataata aatgaaagaa gtttactgta agatataaag
     6301 ttgatattaa ttatcttaaa taaagtgtat ataaatgata aaatataaag agaaatgatt
     6361 gtaaataagt taggctggtt taacttgaag ggatataaaa atggataata taataagtgt
     6421 attgaatgat gttgtttttt tagatataga agttagtgga ttagattgtt taaattcaga
     6481 aattttagaa gttggagctg tcaaggttaa agactggaaa atacatacct atgaatcatt
     6541 aataaaaaac aaatttgagg tacctataga agtattctca gtatgtaaaa atttagataa
     6601 aaatgattta gaaatagcta atgaaataga actggtggaa gatagacttg taaattttgt
     6661 agaagatagt ttcattatat gtcatgattt aagtctgaaa aaaaagtttt ttgagtatca
     6721 tatgccaaag ttaaaaaaca aatttattga tttaattgaa ttagcagtta ttttagaacc
     6781 atatcataaa gattatagct tagaatactt aaaaaatact ttaacaaatt gtaattctaa
     6841 agtggaaaat agagctttat cagatgctat tgatataata aatatagtaa attgcctttt
     6901 agtaaaattt aataactatg aaaaaactac tttggagcca ttgagtttta aaataaattc
     6961 atatcttaaa aaatttaatc ttccaacatg ggaatggagc aaatttttag aagaggcaaa
     7021 ttatgattta tcaaataata taaatataaa aaaagaatat aatatatttg actcaaaaga
     7081 agaaaagaag aaggaaagag aaaccttaaa aattttaaat gaagaagaaa aaaattatga
     7141 agaattatta aaatacaaaa ctatttggga gaataaagaa ggatttacat atgaatatag
     7201 acctggtcaa tatgagctta ctaaaacaat aagagagttg tttagaaata gcgaagatga
     7261 agaaaaaatt gcatgtatag aggcaccaac tggtataggt aaaagtgtag gatatttatt
     7321 gcctgcaata ttagaggcta gaattaataa aaaaagatta ttaatttcta ctgacacaaa
     7381 ggaattgcag atacaattaa taaataaaga tattccaaat gtgttagatt ctttgggtct
     7441 aaatggaaaa gtaagttacg gatatataaa gggaaaaaat aactatattt gtatagatag
     7501 actggaagca tatatagatg attatgagtc tcaaaaccct actaaaggag aaattttatc
     7561 tttaatattt ttgaagagat tagttgaagg tggcaagtat ggagatatag aagaaataaa
     7621 ttatttagtg tttgacaact tcaaggaaat aagtactcac ttaagaaatg taagttgtga
     7681 cccaaatatg tgcagaccta aaaaatgcaa aaaagattgt ttatataaaa acagaataga
     7741 agaattaaaa gaagaacata taacagtagt aaatcattca ctattagcta aatggccgta
     7801 taaggatgaa aaacctttag aaaatataat agtagatgaa gcacataatt tgactgaaaa
     7861 aggatatgat ttcttttcaa gcattataaa ttcaaagtct ttaaggtatt tattacaaga
     7921 aatttatcct tacgagttta ttcaaaatag tagctttata tataaaaaat atagtagaaa
     7981 tatgagaaaa ataaaggctt ttgataaatt ttataatgta ttaaaaattg gaagagaaga
     8041 taaacaaaaa attgctagaa gcataaatct cattattgaa gagatagatt caatattaaa
     8101 ttttggtaat tgtaatgaat ataataatgt aagtaattat aatttaagat gggaactgaa
     8161 tttgcaaata gatgaaattg tgggaaaact aaaaaagggt ggtatagata ctgaaataag
     8221 ttatagagcc tatagtgaaa agataaagtt gagttgtgag aaaataataa aaaatttagt
     8281 ttcaataata ataataattt ataggaatat tgatgatgat agtatagata aagaagcaga
     8341 tatatataaa tttggaaagg caaagacaag agatttagag gatataaaga ttatatttga
     8401 aatcttttta gagtatgatg aaaaggatga ttatgcaagg atagttgaaa ttgataagaa
     8461 ttataatgac tttgaatttc gagtagtgcc attaaaaata gcagatttat ttgaagaaaa
     8521 tattttatct caattagaaa aaggaatatt tttatcagca actttgagtt tatctgaaag
     8581 tatgtcttat tttaaaaata cattaggaat agacagagtt aagaatgtgg aaaagattat
     8641 agaaccaatt tttgattata aaaatagagt ctctgtagtt ggattttctg atatttgtga
     8701 gtacagaaat tctgaatttc caaatgagat gagtaaaatt atatctaata tatcaaagat
     8761 tacagaaggt catacattag ctctttttaa tagtaaagat agacaagaaa aaacttatga
     8821 aatattgaaa aaatacttac atagttttaa cttagaaatt tatgctgata aaaagggcat
     8881 tagacacctt aatgatttaa atagaaaatg tgtagtactt ggctcaaaag gatgttttga
     8941 aggcgtagac attccagggg atggtttggt ttgtgtaact ttagacaagc ttccgaatct
     9001 aaatccaaaa gaccctttgt attttactat aatgaagaag tatggtatag actactatac
     9061 tataaattat cctcaaatga ccataaaggt aaagcaagct atggggagaa ttttaagaag
     9121 caaatatgac tatggatgtt ttgtgatttt tgatgtagga actaatataa gtgttttaaa
     9181 gagattagag aaagatttac acgattgtaa aatttcaaag gttaatagca atgagtttta
     9241 tacttatata aggcgacatt taaataaatc tagaagttta atactaaaat ctgttatatt
     9301 tgatactata aaagcgttga atgttgatgc taaaatggat aacaatgatg ttgataagga
     9361 tattataaaa aaagatataa atgaaaatat aagacaaaga gctgtaaaag gagaagtgta
     9421 ccatattgat attataaaaa aagatatgaa agtaaaatat tttgatagaa actatcttat
     9481 aaatttagat atatttatga gagaagaaga taaaaattaa gagtgggagt gatatatttg
     9541 gcaaaacaaa agttttatgc tgtgaaaaaa ggtaaaaata taggtgtata taatacatgg
     9601 gatgagtgca aaaaacaagt aaatggattc tcaggagctg aatataagag tttttctact
     9661 tttcaagaag ctaaagaata tattgatggg tcagaaaaat tgagttttca agaagataag
     9721 gagtttatag aagcatatgt agatggaagt tatgaacatt cagtaaaaat gtatggttcg
     9781 ggtgttgtga ttttaaaaaa taatgaagtt ataaaaactt atagtgaaaa aggaaaagag
     9841 aaaactttag taagtatgag aaatgtagct ggagagatag aggcttctaa aattgcaatg
     9901 cagtactgta ttgacaataa tgttcaaaac ttgattttat actttgacta tgaagggatt
     9961 gaaaagtggt gtactggagt ttggaaaaca aataaagaag gaactatagc atataaaaat
    10021 ttctatgaca gtattaagaa taagcttaat gtaaaattta caaaggttaa agctcattct
    10081 ggaaataagt ataatgagga agctgataaa ttagctaaaa aagctattgg tgtataataa
    10141 aaaaatattt atacataatt acatggtata agagtatatc taaattccta ctttataatt
    10201 aaacaacttg taattaaaca acttataatt aaataaattt tgattaaaaa agcagattgt
    10261 attatgaaaa aataagtatc taatttataa acaattaata atagtattaa ttagatacaa
    10321 cttatttaat ataataaaat ctgcttttta tataactata aaattttcct acattctatt
    10381 agaattgccc ataaatacct tcaagttctt cttttaatac ttcagggtca tttataccaa
    10441 tagacatggt tctagccagt atatttgctt ggtcataagt tgatgtccat gagaatacac
    10501 cacctagaca atttctaaga acatattgag tttttaagaa tattgataaa gcatcatcat
    10561 atgacattgc aaaatctcca tccttaacta aatatggaac ttgagcagta ttatcaaatc
    10621 tatattcata tccattttta tttatataat cccttctaag ctcatcataa gttcttgtta
    10681 tagtagcacc taatcttcca taaaatggta taccaagaag gattttttca gaaggcattc
    10741 cagcattctc aagatttctt accattgcat caacactata tcctggcaaa gataagtctg
    10801 aatcaaaaag atttgcttga tgttttctac catttgggcc tgtttcacct gctgtaaaat
    10861 cataactcat aagattaaaa taatctatta taggagctat tttatctatt tcagcacttg
    10921 aatttatata tcctctatct cctgttccag ctacactaag ccatttatca tctcctataa
    10981 catctcttat ggcagttagt aagagtgtaa agttttctct atcttgaggt cttgatgtta
    11041 ttccagatgc actacttcca ggatattccc agtctatatc tattccatct aaagcatatt
    11101 catttatcat ctgattgacc tgtcttgcaa aattatatct agatgtaggt gttaatgctg
    11161 catcagagaa tccttcagct ccccaacctc caatagctac aattactttt aagctaggtt
    11221 tttcaccttt aagagcaagt aattgattta aaaatctagg ataaggaata aacaaatttc
    11281 cagactggtc tatctcagca aaagcaaata taactgcatc taatagttga gcatctacat
    11341 tagttggatt tccaagaaca tattctgcta caattggatt tatatctgga cagtttgcat
    11401 tttcaactat tggattgtat gggtctgtta tttgtggtct aactaatttt tttgaatctt
    11461 ttaaagtttt catagctatt tttttagtat ttttttcgct agtataatcg tagtttttat
    11521 aattatgttt atagaaatct tcataactac tatcttcttt atcatagcta gaatttattt
    11581 tgtcgcaaga ttcatcttta tcatagttaa aattcatttc atcacaagac ttatctttaa
    11641 acttatcttg tttggagttg tgaactttgt tagtattttt agtatgtttt ttctcatggt
    11701 tgcaatcatc tttaatatca gtcttgtgtt cttgtttaca atcaagagct ttgttcaggt
    11761 agtcatgatg ttcatgttca cagttacatt cattttcaat gtttttagta tgttcttttt
    11821 tccagctaca agtattatca attttcttgc tcacttcttc atcattataa ttatctggta
    11881 caaaacataa gtaccagtcc atacatgaat atttcttatt acaactgtta actctatttt
    11941 ttaattcctt atagttttta ggataaggta aaatcactgg cattccagga aaccagtttg
    12001 caggagtaac tatattatct ctatcactag tctgaagtgc atctactatt ctaagtattt
    12061 ctggaatatt tcttcctgta gttagtggat aataaagaat cgttcttaga atttgattat
    12121 tatctataat aaatacagag cgaacagttg atgtatcact cattggtttt gatatcatgc
    12181 cgtataactt ggcaattctc atatctctat cttctataat aggaaatgga atttctacac
    12241 ctgtaagtaa agaaatatta tacatccaag ctaaatgtga actgttacta tcaacactta
    12301 gaccaattag ttctgtattt ctttttttaa attcgtcata atatttagca aaacataaaa
    12361 attctgtagt acaaactggt gtaaaatcac caggatgtga aaataaaaca atccaattac
    12421 ccttatagtc agagagtcta ataggaccat ttgttgtatt ggctttaaaa tcaggagcct
    12481 ttgaccctaa acttggcaaa tttggcatgt aaatcacccc tcaataaatt atcatttatt
    12541 ttattctatt aattaataca tattagtgtt actattttat taaaagttaa gtaatcctta
    12601 tgtcaaaaaa agatatttat taaaaagatt taatattttc ctaatataaa tgacaatagt
    12661 aattgctatt tttttactaa tttggtatag taatggataa ggggtagtgt caattttagt
    12721 gattatacga ggtgagtgga ttgaaaaaaa ttctaagaat tttagttatc tccatgatga
    12781 tatgttttgc aatgactttt gcattagtgt taataaattc agttatggga gtacatatag
    12841 gattggatta ttactttttg atgggaagtg tgcttacagt ttgtttaaca attggaattg
    12901 ttttatgcaa tgctagaaaa atatttgata gcaaagctat acacaagaca agaacgaaaa
    12961 ctgtcagtaa taataaaaaa caaaagagtc attctaggga tataaaaaga aagatatcat
    13021 aatttatgta aaggaaatat ttatgtataa aataatgatt gataggtaaa ataaaaacac
    13081 gatttaactt gtgtttttat tttttttcaa gaattatgat ataataacca ataagaaatt
    13141 tagtttacca taaaatataa agattattaa atggagaggg aactataatg aattttagag
    13201 atttatttga gaaggctgta gattttattg atgaaaaaag gaaatctata gttgcgattt
    13261 cattatcaac attaggtgta attgctttga taatagtatt tttcttaagt agtaacgagt
    13321 ttagtgtagg aaatgaagct aatgagttgt taaagattat agagaaaaga cagtattcta
    13381 tagctgttga ttactacaca agtatagaaa aaaagttttc tgattcaaaa atggaaaggt
    13441 ttaataagtc tgtttctaaa aaaataaata aattgctatt aaatagtggt gataaatatt
    13501 tagatggaga cataagtcaa gaaagtttta ttggattaat aaataccgtg aaagaattaa
    13561 acaaaataag tatagatgtg gatgacttat tagctcaagc tgatagagtt agagaaatgt
    13621 ataaagaaga aaatactact tatgatattg ccattaacta cataagtact gtttcaatat
    13681 taaatggtat gggtagtaac ctagatgtat acaaacagaa tatagaaaca atcaaagagt
    13741 ctagagatgt ttatgactca gcagtaaaag accaaaaagc atataagtat tatgaagcta
    13801 ttgaaaagta taataaagta ttaaaagaag atgaaaagta ttacagtatg gctcaaaatg
    13861 ggaaagaaca atgtattgaa gaaatgtatg attactatat aagtagagct gaagaggcaa
    13921 atacttctgg agattatgaa agagcattac aatatattga gtatttaaaa gacgattatt
    13981 cagatgatga aaaggtacag agtttagaaa aaaaatataa aaagaattta tcattgtata
    14041 ctttaacatc tgatgacatt ataaatgtaa tagctaaaaa aagtggcaaa gacaaggcaa
    14101 atctatctat aaattcactt ccacaaatga taaaaaataa taaatactat tatgctgaag
    14161 tatatgagta tgataaatta ataaatgaag ttttggtaag tgcaaaaact aaagatttat
    14221 attcatataa agatggtaaa aaagattaca aagtagatta tggtgatgga tactttagaa
    14281 tattagaaga tggaagttat caatttggca ttacaaaaga taaagctaag tttgtgttaa
    14341 ctaatactct cgatgaaaaa gaaaataagt ataaaaagat tgagatatta gatatagaga
    14401 aagcagatag atatgtaaaa agtaaaaaga gtttagaaga attgtttgga aaatataaaa
    14461 atatttatta ttatgctgta gtaaataaag gcttatttag aggcaaagaa gtttatgcta
    14521 ttaatattta caatgaaaaa atatatgcca tatcagaaaa tggactaaat gaatattaat
    14581 aatattaaat taatatataa ttaaaaagtt tttggggttt taaggcgcat tatgtagtaa
    14641 tataataata gggatatata aataatttta ttgtaaggag aagtatggga tgagtaatgt
    14701 gaacaaaaag ctagttatag ctattggagc tgtagcatta gtagtaataa tttttatagg
    14761 cataatgtgc atgcaattta aaggggagaa aatagcaaaa aacacatatg ttaatggagt
    14821 aaatattgga aaattaacta aatcacaagc aaaacaggaa ttagctaaaa aatacaaatt
    14881 agagaatgtt gattttaatt acaatgataa aagttggaaa gtaaagagca aagatttaaa
    14941 tttatctact gacctggata aaacagtaga aaacgcatat aatttaaata gaaagagtgc
    15001 tttctttggc aatctatcaa aaactatttc agcaaatttt ggcaaaaaaa gcaacttagt
    15061 agttgtgata aattatgata aaaataaatt aaaagcagaa atggaaaaga tagctaaaga
    15121 aatagatgta gatgtaaaag atgctacact tgatataagt ggtgaaaaag tcaaggttat
    15181 accagattct gatggtctta aaatggatat ttctaagagt atggagaatt ttgataatca
    15241 aactaaaaaa ggtaactata aaaatgagtt agtagtaaaa gctactccag caaaagtaaa
    15301 aaaagagcaa cttgctaata tagatacaaa tttaggtacg tattcaacaa catttaaaac
    15361 ttctcaaata aatagaagta taaacataaa attagcaaca gataatataa gtaatgtatt
    15421 acttatgcca ggagaaactt tctcatttaa taaacataca gggaaaagaa gtaaggaaaa
    15481 tggatataaa agtgcacctg taataatgga aggtgagatg gaagaagatt atggtggagg
    15541 agtttgtcaa gtttcatcta cgttatacaa ttctgtgtta tacgcaggtt tagaaattgt
    15601 taatgtaaaa aatcatacta taccgtcaag ttatgttcca aaaggaagag atgcaactgt
    15661 tgcagatagt ggaatagatt tcttatttaa aaataatcta aagcatccag tttacataaa
    15721 aaattacgtt tcaggaaatc aaattgtttg caatatatat ggaagtgcag aagataaaca
    15781 aaatataaca atatcaacaa aattagatgg cgtttcacaa actacaatga aaagagttaa
    15841 tgaccctaca atgcctaaag gtaaagaaaa agtagacaaa agtggaagaa atgcatattc
    15901 tgtatcaaca tatagaacat ttaatgatgc aaatggtaaa aaaattaaaa ctgaaaaaat
    15961 agctaattca tattatccta agaaggaagg tattatatta gttgggacta tggaaccaaa
    16021 accagaggaa aaaccaaata cagacgaaaa taagaataat caaaatacaa acaatcaaaa
    16081 tccaaataat caacaaaaac cagaaacacc accaactgat aataagccta atgagacaca
    16141 accacaaccg caagcttaaa gttctcaaga ataggattta tgtagagtaa taaaaaatat
    16201 aaatctaaat aggagggatt actttgaatt taaataatat aacgaattac gttcaaagta
    16261 tttgcgagaa tatttctaat gtcttggatg tagatgttac tttagttaca aaagatttaa
    16321 ctaggatagc aggtacagga atattcagag gtaaaatagg agagacaata tcagagaagt
    16381 cagtgtactc tcttgtttta aaagatggga aatcctatgt tataaataaa gaaatagaag
    16441 agaactgtaa taaatgtgca aatagagaaa attgtaaaga gttagctgat atatgtactc
    16501 ccgttaaaat gggagagcat atacttggaa tcttgggtat agctgcgttt aatgaagaac
    16561 aaaaagaaaa gatactttca aaagataagg agttaactgc ttttgtaagg agtatgtctg
    16621 atttaatatc ttttaaacta gatgaacttt ataaacaaga agttaagact atagatgacc
    16681 ttgagaggga agctatagaa aatgccataa agaaatatgg aagtaataca gaaggtatga
    16741 aaaaagtagc tgaggcatta aatataggta tagctacact ctatagaaaa gtaaaaaaat
    16801 tcaacattaa aagttaatag tattgaaaaa gaggtaacct ttttatgaaa agaagaggat
    16861 tacctttttt attatgagaa tggtggaaaa atatgtatag ttttgacttg acatattaaa
    16921 tatgttatct taaatatata ttttagagtg gaggtgagta ttattttagt taaagatata
    16981 aaacaagaca tagaaagcat gcctagaaaa attttagata tatctttgat agaagataat
    17041 aaaagtgatt tgactttttt taatatagaa gaagaagacg gtgatgaaac attaaaagca
    17101 ttaaaacaga gttatgtgac tacaaattat aaagaagaaa ctctattaaa cttgcaagga
    17161 gctttaaatt caaagtcaga tacaacgtct aaggagttaa aattagaatc atataaaaga
    17221 tataacaatg cattggattt agcatataaa aattatataa ctagtgccat taatatggtt
    17281 aataaagctc tggagataaa tcctaaagac attgatatac taaatcttag aggtctttta
    17341 aaattattaa aatgtgattt tgctaaatca tttgagagtt tttatactgc tttatgttat
    17401 gaaaataatc atatatctag aaaatatgta aatctaattt catctgaaga ttttaaaact
    17461 tttttaggaa gatacaatca ttctataaga tttataaatg aagaattaaa ttatgagtca
    17521 atacatattt tagagaacat aattgaagaa gaacctgaac taatagagcc atatgtaatt
    17581 ttatctttgt tatatgataa actaggtaat gtaaaaaaga gagaaggata tttagacaaa
    17641 cttaaagagc tagataaaga taatcctgta tttgaaaaaa atgaagaaga aaaagaagat
    17701 acaagtaaaa aggaagaaat aaaaaaagta aaaagaaaga aaagtatttt gccatatatt
    17761 atagttggct gtgttttaat aggtatgggg atatatttga ttcaaagcaa aaagagaata
    17821 gaaaacttga ataaccaaat aagtagtaaa gaggaaaagt taagtgaaac tgataaaaag
    17881 ttaggagaaa cgagtaaaaa attagaaaaa acgaataagg aattaaatga ggttaaaaat
    17941 aaagaaccag aaagagagat aactgtagct gatgaggaag atttatatta tcaagctcta
    18001 aatttaaaga aaaacaaaga atatgaaaaa gccatagata attttaaaag tgtagtttct
    18061 tctggtaaaa ctaaaaaata tatttctgag tcaatatatc aattagcaat aacaaataaa
    18121 ttattaggaa ataaggatga agctataaaa tattacaaaa aatatataaa tacttatact
    18181 aaaaatgacc agtattatga tgattcatat tacgagttgg gtatgcttta ttatgataat
    18241 ggcgatttaa aaaatgcaca acagactttt tatagtttga gaagtgaagt tccagacagt
    18301 atgtataaca attcaaaaat aaaagaaatt ttaagtgaaa aataggttta tatagttaag
    18361 ttttttgaaa caaccaagta tgtattttat taaattaaaa taaaaataaa tttaaaaaga
    18421 gattgtgtca aattataact ttctatttta aagaaagata tttgcttgtt gataaaacta
    18481 caaatatatg atttgaagca atctctttaa tttttggagg tggaaaatga aagttttcaa
    18541 tcaattagta ataattttat ctatctgggt aataggagag tatataagtt cctttataca
    18601 aggaattata cttattcctg ggagtatagt tggtatgcta ttattatttc tactactaca
    18661 atttaaagtt ttagacttga gtagtataga aaatgtaagt ggatttttcc tcgataatat
    18721 ggctatattt tttattccag caggtgtatc acttataaag tcattagacc taataaggga
    18781 aaatgtatta gtgcttttat tagtcatatg tttaagtaca ctaatagtaa tgtatactac
    18841 tggaattatt gtggagaaaa tgataaaaaa gaaggaagaa ggacaaaaaa atgtataatg
    18901 tattacagac accagtattt ggtataatag taacaatagt ttttttcaat ttaggaagat
    18961 acattcaacg aaaaacaagt aatcctatat gtaacccttt attaattgca atcgtaggaa
    19021 taatattgtt tttaagcata tctaaaatcc cttatgagaa ttacaagata ggagctgata
    19081 gtctaaattt ctttttaggt cctgtcacag tagtacttgc agttccactt tataaacaat
    19141 ttgaattatt taaaaagcat atgtttgaga ttattgtagg aataggttgt ggtatagtga
    19201 tttcttttgt atctgtattg ataattggca aaatagctaa ttcagatgta agtataataa
    19261 attcactaat tccaaaatct ataacaacac caatgggaat atctttagca aattctttaa
    19321 atggtataga atcaataaca gttgtagcca taatttttac aggtattttt ggtggtatgg
    19381 ttgcttctac agtattcaaa ctggggaata taaatcatcc agttgctaaa ggaattgctc
    19441 ttggaacatc tgcacatgct ttaggaacta caaaggcttt tgaacttgga gaaatagaag
    19501 gagctatgag tggtgtttct attggagtct ctggtacaat tacagtaata ctaattccaa
    19561 ttataatgaa ttttatataa aaaataaaat taagacgagt accttgaata cttaaaacaa
    19621 aataaaataa aaaaaattta aaataaaaac tgaacgaaaa aaatgcaaat aatgaaataa
    19681 aaaaatcatg tactgaaatt ataaaaagaa aaatttcatt taggaattaa ttataaagag
    19741 acaattacta aacttgaatt tgctaaaata aaataaatta ctgcgaaaat agatatttag
    19801 aaaaaaatac tataaattta ctatattgca agttaaataa taagcagtat catattatgc
    19861 tagaaaaagt ttcatttaag gcataaatga gatgatttga acgtttttaa agattagaat
    19921 ataaaagatt gcactagaca tatatgaaaa agataatata atagatgatg taatagatga
    19981 cagttcaaga aattataaaa aaaatttatt tgaaatatta tctattacat caggaataat
    20041 atatgtaaga gtaagctttt aaaattctaa agatttagaa agattgaagg gagaaagaaa
    20101 tgagtgaagt taagaatacc ctacaaaaac atccagtttt aagatattca acaatgctat
    20161 ttgggatgtt gatgacatct ataggaataa atgggttctt aagaccagca catctactta
    20221 gtggaggtgc tacaggtata gcaacatcta taaactattt gacaaatata aatgtaggtt
    20281 tattaacatt tttaatcaat attccaatat ttatcttagg gttcatatac cttgaaaaag
    20341 agttttgtat ttcaagtttg gtaaatatga ttgtattttc attattatta ggagcaactc
    20401 aggaaataag taatattata cctatacatg atatattgct tcaaagtgta tatggtggta
    20461 tattatctgg tttaggagtc ggagttgtat ttagaactag gtcttctcaa ggtggtacag
    20521 atataatagc tgcaatacta aaaattaaga agaatataga aatgaaagac actgctttag
    20581 caataaatgg cttgatagta cttacaggaa gttttttatt tgggttggat ttagcattat
    20641 acactcttat aggtctattt ctaaatgcgt attcaatgag ttttattaaa gatgcaatga
    20701 attaccaaaa atctgttatg gtaatgtcaa atgaagtcga tttaatagca gaagatataa
    20761 tgaagagttt agttagaggt gtaacttttt tagatgcaga aggtgcatac actcatcaaa
    20821 aaaagaagat tatatataca atagtttcat caaatgagat accaaagata aaagatatag
    20881 ctttgaagta tgataaaaag gcctttatat ctgtaaatga tgttacagaa gtaaagggaa
    20941 gagggtttaa agcaaaagat ttatagaaaa ttttacaagc tgggagttta taatgtaaat
    21001 ttgtatatta tatctctcag cttatttaaa tttagtatac gaaaataaag gttttattaa
    21061 tgatttgtgt atcactttaa aagatatcat tttaaaatta aaattgaaaa aattacttaa
    21121 tatgtagaaa acatgaccac tattaggata taataaattt aatagattta gtaaaatatc
    21181 taggaataac gttggaggaa tggcattatg aatttatcta aagaatatgt taatttgtat
    21241 gataattatt tgaaatatat aaatgaagta aacaaagaga ttagaagtat aaagaacatg
    21301 aagaaacgtg ttttaaaaag gggcgatttt gctccagaaa atgaagtatt agaattggaa
    21361 ggaaaaacaa tacgcgatat agatgatgtc gatacaaaaa aaccaaaaaa taaaatctat
    21421 aaattttcaa atggggatgt atatgtaggg aaattcttag agggaaagat ggaggggaaa
    21481 ggctcatata ctttttttgt agatgaagga acagttatgg agtacatagg agaatttaaa
    21541 gaagataaaa aaaatggaaa aggaaacttt atattttcaa atggaaatga atatataggt
    21601 tattttgagg aagatatgat gagcggtatt ggaaatatgt tatatagtag taaagatgaa
    21661 tatattggaa cttggaaaaa cggaaaaaaa gatggaaaag gtatttataa gtggagtgat
    21721 ggatgtatat atgcaggtga atttaaaggt ggaaagatgg aagggtacgg tatttgctat
    21781 aatagtaaag gggaagtact ttatgaagga gaatggaaga ataatttgat tcatggtaag
    21841 ggaacttata tatgggaaaa aggtaaaaag tatataggtg aatttatgca tggtaaaaaa
    21901 catgggcaag gaacttttta tctaaataat gaattggttt atgaagggac ttggaaattt
    21961 gataagccat ctatatttga tagaacatta gatgaaatat tttccttgag actgtagctt
    22021 tatctaatta gtagataaag cttttttcta atacttactg taaataggta tgaatgatat
    22081 tgattagtat acactatcaa tattaactta ataaatgcaa tattaaaaaa ttttgattga
    22141 ttttaagaag gagagatata ttgaagagat taattgcttt agtgttagta gtacttattg
    22201 ttttatttta tagtcctgaa ttattaaaag aaggatatga tttaaaagaa aagttttttc
    22261 aaagtgaaat atggaatgaa tttttagaca aaataaatat aaatgataat tctaagaaag
    22321 ataaaaaaga aaaaagtcaa aatttacaat caaataatac tgaaggggag aacttaggag
    22381 agtcagatat aaagaatttt gaaaaaataa gcttaggaga taatttaagc tatgttttat
    22441 caagtattgg taaacctggt agaattgata ttagtgaata tggttttgat tggtacgtat
    22501 ataatcaata tggaaaagaa tttgcaatgg ttggacttga aaatgatgaa gtagtagcac
    22561 tttatagtaa ttctattaat tcatgtgaaa atcaagatat aaaactaaat caagatagac
    22621 aaacagtgag aactaagatt acaccattaa aatataagag aaaaggaaat accagatata
    22681 taataaactc agaaaatcaa tatgatataa taagtaagga aggtaagtat attacaattt
    22741 tctacgatat tcatgaagaa aatagagtct gttcatattt aataattgat aaaagcactg
    22801 aagatgagtt taaaaattta tatccagatg atagcgaaga acttaaaaaa tgttttgaac
    22861 ttgaagttat agaccttgta aatagtgtta gaaatcaaag agggttaaac tcattgagat
    22921 acagtgaaca ggcaactttg agttcaataa aacatagtga agatatgaga gataataatt
    22981 tttttgacca tgtaaataag aagaatgaaa ctccatttga cagaatgaaa agagaaggta
    23041 tagtatatac ttcagctgga gaaaacatag cagcaggaca gattaatgca atatatgcgc
    23101 atgaagcttg gatgaactct gaaggacata gaaaaaatat tttggggaac tataataata
    23161 ttggagttgg agtaatattt ggaggaagct ataaaacata ttacactcaa aatttttata
    23221 aataactaaa atatttgaaa ggaagttaaa aaatgacatc atggaaaaaa aagacagtat
    23281 ataagtgctt aatagcagta gtcttgtttt gtggaatagt gttaatatct aattttagta
    23341 aagtttctgc tttgatgatg gatactaatg gaaatgtttt gattaaacat ggttcaaggg
    23401 aaaaaaagct aatagcaatt acctttgatg atggtcctca tcctaaagaa actagtcaag
    23461 ttttagatgt attaaagaaa tacaatgtaa aagctacttt ttttatagct ggaaaacatg
    23521 caaaatggta taaagaacca ttagtaagag caagtaaaga aggtcacgag ataggaaatc
    23581 atactttcaa tcatcctgat ataagtaatt taagttctag tcagatagaa gaggagattg
    23641 ttaagtgtga agacattttg aaagaagtaa ctggaaaaaa accgacatta tttagaccac
    23701 catttggaag ttatagagaa aaagaattaa tagaaattgc aaaaaagcat gactataaag
    23761 ttgttttatg gacaggtgta gatgtgaaag attggaaaaa tccaggagct aatagcattg
    23821 cagataaaat aattaataaa gtacaaaatg gagatataat acttttgcat gattatgcaa
    23881 ctaatgatac agttgaagct ttagatatgt ttattccaaa aatgattgaa aaaggtttta
    23941 aatttgtaac agtttctgag ttgataaaat aatttttagg ggggagattt acagtatgat
    24001 tcttatgata gacaattatg attcttttgt atacaaccta gtccaatata tagaagaatt
    24061 aggggaaaca gttgtagtaa aaagaaataa tgaaatcaaa ataagtgaca ttgaagaact
    24121 aaatccagag gtaattgtgt tatctccagg accgtgttct ccaaaagaag ctggtatttg
    24181 catagatatt gttgagcatt ttaaggggaa aaaacctata ctaggaattt gtttaggtca
    24241 ccaaactatt ggacatgttt ttggaggaga tattataaaa gcacaacagc ctgtgcatgg
    24301 aaaagtatat agtatcaacc atactaataa aggagttttt aggggactta aaaatccttt
    24361 aaatgtcact aggtatcatt cactaatagt tgactccaat acagttccaa aagaattaga
    24421 aattacagca attactgata aaggggaaat aatggggatt aggcataaga aatatttaat
    24481 agaaggagta cagtttcatc cagaagctat tttgtcagag tatggtcatg aaatgcttaa
    24541 aaattttata acagaagcta gagaaagggt acatatgtaa tatgataaga gagataaata
    24601 ctaaattaaa ttcttttgag atatttacta tttttagaaa tgaacatgac agttttatat
    24661 tagacagtgc tatggataaa gaaaaattgg gaagatattc ttttataagt agccaaccat
    24721 ttaaggtatt aaagtataaa gatactgatg aaaatccttt agaagtttta aaagaagaac
    24781 tacataagta tagggttgta aatgatacta atcttccatt tgtaggaggt gctgtgggat
    24841 atttatctta tgatttaggt aattacatag aaaatttacc tagaactgct gtagatgata
    24901 ttgagatgcc tgatatgtat tttggatttt ataatcatgt aatagttata gaccatcttg
    24961 tgcaaaaaac ttatatagct actccaaaca tagatatcga attagaagaa aagataatag
    25021 atgatataga acaaagaata ttaaaagaag agaaaaaagg tatagatagc atatgttatg
    25081 aagaaaaaga agtaacatct ataagactta aatctaattt tacaaaggaa gaatttaaaa
    25141 atgcagttca aagtgttaga gagtacataa gacaaggaga tatatatcaa gctaatttaa
    25201 cacaaaggtt cagtggagaa acagaactta caagctttga attgtatagg gacttaagaa
    25261 gatttagccc agcaccattt ggggcattct taaactttga agatgcacat atattatcaa
    25321 attctccaga aagatttata agatgtgtta ataagagaat agaaactaga ccaataaaag
    25381 gtactcgtcc aagagggaaa gataaagaag aagatttaag acttcaacaa gaacttagaa
    25441 atagtgaaaa agatagagct gaactactta tgatagtaga tttagaaaga aatgatattg
    25501 ggagaatatc taaaactgga agtgttaaag ttccagagct atttgtaatt gaaccatatg
    25561 caaatgtaaa tcacttagtt tccacagttg taggtgagtt aaaagatgat aaagatgcta
    25621 ctgatgtaat aaaagcaact tttccagggg ggtctataac aggagcacct aagattagag
    25681 caatggaaat tatagacgaa ttagagccaa cgcaaagaaa tgtatatact ggttcaatag
    25741 gttatatagg ttttaatggt gatatggatt ttaatatagc aattagaaca ataatcaaaa
    25801 atgacaaaaa agtctacttt caagttggag gaggaatgac ttgggattct gacccagatg
    25861 aagaatatca agaaacactt gataaagcta aatccataat gaaggctttg aggggatatt
    25921 atgaagaata atgtaggttt tgatagtagt ttaagtaaat ttggaattgg tttgtttgaa
    25981 actattagag ttaaaaatgg aatagcagta gatttagata tccatataga aagaatgcta
    26041 agctcaataa attgtttgga tttagatata aactatacaa aagatttctt gataaatgaa
    26101 attgttacat atataaaaaa agaaaatgtc attaataaag cacttagaat tactgttttt
    26161 gatgaaggtt ataatatatc tattagggat gttccatata atcaagagac gtatgagaag
    26221 gggtttaaat tagctatatc tccaatagtt agggggaata gtttaattca tagacataag
    26281 actactaatt attttgaaaa catatatacc aaaaatatcg caaataagac tggttataat
    26341 gatggtatat ttttaaattc agaaggtgta atattagaat gttctatgag caatattttc
    26401 tttataaaag gagaaagagt gtacactcct agtgatagat taccgatatt aaatggaata
    26461 ataaaaaaaa ggattataga gatttgtgac gaattacata tagagttgat agaaaatgaa
    26521 attaatatat cagaaattag tagttttgat tttgtttttg tcacaaatag tcttatgggc
    26581 gctataaagg ttacagaaat tgacaaaata aaatttaata aagaaaatgt tgtttttgat
    26641 aaaatagtga agttattaga ataaattaaa atattaacaa tttgttggag acaaaagatg
    26701 ataggttgta tttatgaagt atacaatgaa gagataacta aaataataga aaaccaaaac
    26761 actttggctg tatatttagt gggttctagt aaagacgtag attttactct ttatgatgta
    26821 gagataaacg atattgatgt gttcgttttt gtaaaagaag gggaaaaaca agagagaata
    26881 ctgtttaaaa aaaagggaat agaatttgat gtaaattact tttcaaaaga tggtgtaaaa
    26941 aaattattat caaataggga atatttcttt gtgaaagaaa tgaaagatgc taaagtactg
    27001 tttgataggg agaatatatc acatattata aaagatataa gtagaaatat ttacttagaa
    27061 ggacccagta aaatgtcatt agaggaaaag tcttttataa agcaagatat tggagcaaaa
    27121 atatcgaatt taaaaaataa agaaaaattt gatgtttttg aatatcattt tttgacgaat
    27181 ttatatttaa aagatataat aattgggtac tttaatataa atgataaatg ggtaccaaaa
    27241 gacaaaaaat tgctaaaagt tttaaaaaaa gaaaataatg agctttttga actagtgtca
    27301 aaagtaagtg aaaattatga ctatcaaaga cttttagatg tttataatta tatttttaaa
    27361 gaaattgaga caaaagaggt tataaaacta atcttctagt cacaaatcaa tggggggagt
    27421 ttaaatgaat aaagttgata aagaaaagat acaacatgca gtaagagaaa tactagaggc
    27481 aattggggaa gacccagata gagaaggtct aatcgaaact ccaaatagag ttgctaggat
    27541 gtatgaagag atattctctg gtcttagtga agaaccaaga gaccatttaa aagttctttt
    27601 tgcagatgaa aaacatgaag agttagtatt ggtaaaagat attccatttt attcatgttg
    27661 tgagcatcat ctagttcctt tctttggaaa agctcatatt gcttatttac caaaaggagg
    27721 aagacttaca gggctttcta aacttgctag agtaatagat acattggcaa aaagaccaca
    27781 attacaagaa agaatcacta aaaatgctgc agatataata atggaagaat tacaacctta
    27841 tggtgtctta gtagtagtag aagctgaaca tatgtgcatg acaatgagag gcgtaaaaaa
    27901 accaggttca aaaactgtta catcagcagt gagaggaata tttgaaaagg acattgcgtc
    27961 tagagccgag gctatgagtt tgattactat gaagtagcaa tttattatag atataatcat
    28021 ttattgagat aaaatttaat ttaagggagt gtcattaatt gtgtttgatt atggtaaaag
    28081 aacttatata atgggaatat taaatgtaac tccagatagt ttttctgatg gaggagattt
    28141 taataacttg gacatagcaa tacaacatgc aaaagatatg gttgaccaag gtgcagatat
    28201 aatagaccta ggaggagagt ctacacgccc aggtcatagc tatgtagact cagacgaaga
    28261 gctaagaaga gtaatccctg taataaaaaa acttaaacag gaattggata taccaatatc
    28321 aatagacact tataaggcag atgttgcaga agaagcatta aaattaggtg tcactatggt
    28381 aaatgatgtt tggggcctta gaaaagataa aaatatggct tctgtaatag gaaaatatga
    28441 tgcagaagtg tgtataatgc ataatcaaga tgggacaaac tatgacaaag atataatgga
    28501 gtcaataaaa gactttttta aggtaagtat agaaatggca atgagttatg gtgtaaaaaa
    28561 agaaaaaata gtacttgacc caggtgtagg atttggcaag gattttgaac aaaatattga
    28621 agtattgaga agattaaatg aattaaaaga tttagggtat cctattttgc ttgggacatc
    28681 cagaaaatca gtaataggaa aagtacttcc agttgagcct aaaaaaagat tagaaggtac
    28741 aatagctact actgttcttg gtataagaga tggcgtagat atagttagag tacatgatgt
    28801 ttatgaaaat ttaatggcag ctagaatgac tgatgcaata tatagaaagt aggtataata
    28861 taatggataa aatattactt agtaatctag gattctatgg atatcatggt gttcttaaag
    28921 aagaaaattt tctaggtcag aaattctttg tcgacatgga actttatatt gattcaagag
    28981 aagcaggtct tagtgacgat ataaataaat ctgtaagcta tgccgaggtt tacaatgttg
    29041 ttaaagatat tactgaaaat aaacaattta atcttttgga ggctttagcg gaaaatattg
    29101 ctgaagaagt cttgaataaa tttatactta taaatggagt tagggtcaga gttagaaagc
    29161 ctgaggctcc tgtaaatggt atttatgact attttggtgt tgagataagg agagcaagag
    29221 atgaataagg cttatttggg aataggtact aacatgggtg atagatttga taatttatca
    29281 agagcatgtg aacttttgaa aaatagtgat tctatatata aagtaaaaga atcaagctta
    29341 tacgaaacaa aaccatgggg atatacagaa caagcagatt ttctaaatat gtgtgtagaa
    29401 atagaaacag agtttgaacc ttatgagttg ttagaatatt gtcaagaaat agagagagaa
    29461 ctacacagag agagaatagt tcattgggga ccaagaacta tagatgtaga cgtactattt
    29521 tttaatgatg tagtttccac tgatgaaaga ctaacaatac ctcatccaag gattcaagat
    29581 agagctttcg ttttgatacc acttatggat ttaaatgaaa aacttataat aaatgaaaaa
    29641 acaataaaag aacatttaaa cctcctatct gctgaagaaa gagaagaagt aaaggagctt
    29701 gtaggttatg aaagaaaacc tatttaataa taattcaaag atagagataa atacaaataa
    29761 caaaaagata actgtaaaaa aagataaact tataatagct ggaccatgtg caatagagag
    29821 ttatgagcaa cttttggaga ctgctaaatt tgtaaaaagt cagggagcaa atattttaag
    29881 aggtggagca tacaagccaa gaacatctcc aaattcattt caaggattaa aaaaagaagg
    29941 tcttgaaata ttaaaagcgg ttaaagacga agttggtatg gctgttatta cagaacttat
    30001 ggatgtaaga gatatggacg aactgtatag tataagtgat ataattcaaa ttgggtcaag
    30061 aaatatgcaa aactttactc ttttaagtga agtgggaaaa caaaataaac ctgttatgtt
    30121 aaaaagagga atagcatcca caattactga atggataggt gcttctgaat atatagcaat
    30181 agaaggaaat agtaatatta taatgtgtga gagaggtata agaacgtata atgattatac
    30241 tagaaataca ttagatttag ctgcggtacc cattattcaa aaggaaacag gtcttcctgt
    30301 tgtggtagac ccaagccatg ccactggagt tagatatttg gtaaaaccta tgtcactggc
    30361 atcttttgca tgtggagcag atggaataat ggtagaagta catcctgacc cagaaaatgc
    30421 tttgtcagat ggtgctcaat ctctttgctt taatgaattt gaagatttaa tgaaatcaat
    30481 taataattat taaaagaggc aagagcctct tttttattcg taatcgttgc tgaggtaaat
    30541 ttataagtta taatttgata gttagattat ttaatataaa taaagattta atattgatag
    30601 aattaatata aaaaataaaa attttttgat taataagaag gatatcaata aaaaaagtcg
    30661 aattgtgtat attgagtgat tgacaaattt agaatatagt gtagaataga aatgttaaca
    30721 caaaaaatta caccagaagg tgataatatg aatgatataa aagacattat tgaagaaata
    30781 aaagctagat gcgatatagc aagtataata tctgaatata tgaatataaa acaatctgga
    30841 gctaattaca aaggattatg tccatttcat ggcgaaaaga caccttcttt ttatataaat
    30901 acatcaaaac agatttataa gtgttttggt tgtggtgaag gtggagacgt aataaatttt
    30961 gtcatgaaaa tggaaaattt ggattttatg gatgctgtaa aaattttagc aaataaatgc
    31021 ggtatagaaa ttaatactaa catgaatgaa gaaactagga ttaaaataga aaaatctaag
    31081 aaatttcaag atattcatac ggaagcagct agattttatc tttcaaactt attgggaagc
    31141 aaaaatcttg ggtatgaata tttaagaata agaggactag atgataaaat tattaagaaa
    31201 tttggtttag gattttcttt ggattcatgg aattcactta tgaatactct aatcagtaaa
    31261 ggatataaaa aacaagactt attggagtgc ggtctaattg caaaaaatag agatggaact
    31321 aattgctatg ataaatttag aaatagagtt atgtttccta tattcgatta tagaggaaat
    31381 ataataggat ttgggggaag agtattagac gattctttgc caaaatactt aaattctcca
    31441 gacacattaa tttttaataa aaaacagaac ttatacggat taaattttgc tagaaaaaat
    31501 ttagaaagta aaactatagt cttagttgaa ggatatatgg atttaatttc actttatcag
    31561 tatggtataa aaaatgtagt agcaaccctt ggaacagcct tgactgaaca acaaggcatt
    31621 ttaataaaga gatatgcgga cactgctatt atatcttatg attctgatga agcaggaata
    31681 aaagcgactt taagagctat agatatactt actaaattag gtatcaatgt aaaagtgtta
    31741 gacttaaaag atgctaaaga cccagatgaa tttgtaagaa aatacggact tagtgattat
    31801 aaaaaagcta tggatgtttc tactcactac ataaaatata aaatagatca tcttaaaaaa
    31861 gaatttaaca ttcaaaaaga tgaagaacga gtgaagttcg caaaagaagc ttctaaaatt
    31921 ataaaacaat tgacaagtcc tgttgaaatt gatttttata caaagtattt aagcaatcaa
    31981 atagatatta atgtcgagtc tataaagaga gaagtttatg gtaaaaatta caataagcca
    32041 tataataaca aaaatcaaaa gaaaatagaa gaaaaagtaa ttgaaaaagt cgaagtcaga
    32101 caagacggaa aacaattagt tgaagaaact ctaataaaaa taatgttaga agacaaaaaa
    32161 attagagaaa tagcgttact taaagtagaa gaaagtgatt ttttattgaa agaaagtaaa
    32221 gaaattttaa attacatgat taaaaatcaa gaattggaca aaataactat tgacaaattg
    32281 aaaagtttaa acatatccga agaatactta aaagaattaa attcaatttc tttgaatagt
    32341 ataaacttag agaacacaaa agaaatagaa ggaataataa caaatatcag aaaaaactca
    32401 ttagaagagc aaattaatag cttgttgaga gaacaacaag aattagaaaa taataatgat
    32461 atgaaagagg tagatggtag agttatggaa attgctttaa aaatagttga gataaataaa
    32521 attttaaaga gcttgtagag aaaggaggtt tgagtgtgga aaataaatcg aataaaaaag
    32581 agttaaaaaa ggttactgct aagacattaa tagaaaaagg aaaaaagcaa ggttctctga
    32641 cacttgcaga gataatggaa gctttttcgg agactgaact tgataaggat caagtagaaa
    32701 atctttatga gactttagga aatttgggaa tagaaataac agaaacaaaa aactataaag
    32761 ctgatataga tttttcggtt gctgatgacg atttaagtat aggccactta gatgaagatg
    32821 cagaggcaat ttcacatgat gactcttctg caatagaaat agaaactgtg gatttatctt
    32881 taccaaaagg gataagtata gatgaccctg taagaatgta cttaaaagaa ataggaaaaa
    32941 ttcctctact taaaccacat gaagaagtag aatttgctag aaggatgcac gaaggtgatg
    33001 agatagcaaa acaaaggtta gttgaagcaa acttaagact agttgtaagt atagcaaaaa
    33061 gatatgtagg aagaggtatg cttttcttgg atttaataca agagggaaat ttaggtctta
    33121 taaaagcagt cgaaaaattt gactatacaa aaggatataa gtttagtact tatgcaacat
    33181 ggtggataag acaagctata acacgtgcta ttgcagacca agctagaact ataagaatac
    33241 cagttcatat ggtagagact ataaataagc taataagagt atcaagacaa ctacttcaag
    33301 aacttggaag agatccaaaa ccagaagaaa ttgcaaaaga aatggaaatg acagaagata
    33361 aagtaagaga aataatgaaa atagctcaag accctgtgtc tttagaaaca ccaataggag
    33421 aagaagaaga tagccattta ggtgacttta ttccagatga tgatgctcca gccccagcag
    33481 aggcagcagc atattcttta ttaaaagaac aaatagaaga tgtacttggt tcattaaatg
    33541 atagagaaca aaaagtatta aagcttagat ttggtcttga ggatggtaga gccagaactc
    33601 ttgaggaagt tggaaaagag tttgatgtaa ctagagagag aataagacag atagaagcaa
    33661 aagcactaag aaaactaaga catccaagta gatcaaaaaa acttagagat tatttagact
    33721 aaaaagatac atcattgatg tttttgtgat aaatgccatg agataagtga tatctcatgg
    33781 ctattttgta gtaaagattt aattttattt ttgtagttat ttcagtctaa tatctataac
    33841 ttggattaaa tcctataaat aaagggaatt gaaaggagaa ttatatttga aattaacaga
    33901 tagattattg aaaatagcat cattagcgtc agatggtaaa aaaatagctg atatagggac
    33961 ggaccacgga tacataccag tatatttgtt aaaagaggga aaagtaccat ttgcagtgct
    34021 agcggatgtt aataaaggac ctcttgacaa tgcacataaa gaagtcatac agaacaatct
    34081 tttagataaa gttgatttac gattgggttc tggtatagag atacttgaaa taggggaagt
    34141 agaagaagtg ataattgctg gtatgggtgg aatcttgata agtgagcttc tcgaagctaa
    34201 aaaagaagta gcacataatg tagaaaaatt aatattacag ccaatgcaag cacaagaaga
    34261 acttagatat taccttttaa acaacggata tgaaatttta gaagaagttt tagtgagaga
    34321 agattttaga atatatgaga taattgttgc caaatataca ggtaaaaata ctataataga
    34381 agatgagata tattatgagg ttggaataaa gcttttagaa aacaaagatt ctctttttaa
    34441 tgattttata gaaaaaaaga taaagacata tagttctata gttaataaat tagaagggaa
    34501 aaatggggaa gctatagata agaagagaaa ggaaagcgaa gttgcaataa aaaaacttga
    34561 aaatttaata aaataaatag gaggtatata tgctattaaa gagtctaact agaaaaattg
    34621 aaaaaaagta tcctctaaac ttagcagagg attgggataa tgtaggtctt atagttggag
    34681 attttgatat ggatgtaaaa aaggtattgg tatctttaga agctaatgaa gatgttattg
    34741 atgaagctat atccaaaaat atagatttaa ttgtgacaca tcatcctttt atatttggga
    34801 aaattaataa aattaatagt ggagatttaa aaggcagact tatccaaaaa cttattaaaa
    34861 atgatatatc actttattct atgcatacga attttgatat agcatttgat ggtctaaatg
    34921 actattttat ggaaattatg gaatttggta attcaaaggt tttagatata actaaaagcg
    34981 aaaatttgta taaattagca gtatacgttc cacataacta ttcagatgaa cttagaaagg
    35041 ttttaagtaa ttcaggagca ggtcatatag ggaattatag tgattgtacg ttttcaacag
    35101 aaggtgaagg acaatttaag ccattagaag gctctaatcc gtttcttgga agtgtaaatg
    35161 atatagaaac tgtaaatgaa gttaaaattg aaactgtagt accacagaag cttttaggtg
    35221 gggtaataag ttctatgtta gatgcacatc cttatgaaga agttgcatat gatttgtaca
    35281 agttagaaaa taaaggtgag atatttggac taggtagaat aagtaaactt gataaaagta
    35341 tgacattaga aagtctttca aggaaaataa aagagaaatt aaatatgaaa cacataagag
    35401 tagttggaaa ccttagtaca gacataacga aagtagccgt tgtaacagga gctggttcag
    35461 aatttgtaaa aaaagctaag agacaaggtg cagaagtact aattacgggt gatgtaaagt
    35521 atcatgaggc acaagatgca cttgatattg gaatgtgtat agtggattgt ggtcattttg
    35581 atacagaaga tatattcaaa aatgttatga agagattttt agatgaattt agtgaaattg
    35641 aagtaataaa gagtaatgta tatttgaatc catttagtac tatttagcag tgtttgataa
    35701 taaaaatact atataaaaaa taaatttgag tttaattagg gggataatga tgaaagtagc
    35761 agtaattttt catagtgttt gtgggagtac atatttatta gctagagaat ataaagaagc
    35821 gcttgaagaa atgaatatcg aggtagatat atttagagta agtgacgaag ttgcaaaaac
    35881 acttcctcaa tattatttga taaattccaa agaatacaaa gacgaatttg aaagtataaa
    35941 tgtaattaaa tctggaaaag aaatattaga ttatgatgct atatttatgg gttcaccaac
    36001 atattatgga aatgtatctg gaccaatgaa gatgtttatg gatagttttt ctgatatttg
    36061 ggtaggtgct cctttgagtg gtaaaatatt tggttgtttt gctacagcag gttcacaaca
    36121 tggaggagga gaattagctt tgcaagctat gaatatattt gcccaacata tgggaatgac
    36181 tcttttgtca gttccatgtt cagtaagagg aggttatcca gcgtatggaa tacttcatat
    36241 agcaggagat aattctgata taagaccaaa tgatgatgcc aagatgggta taagagatta
    36301 tctaaaaaga cttaacatat aagaatatca tataaaaata cctaaaagcg actgtatata
    36361 cttttaggta tttttactta attataaacg tgaagcttta ccagaaatat ggtcaatttc
    36421 tattttaaca acagttgtta agttcatatc cttctctatg tacttcatgc cttcttcaaa
    36481 gaatccttta gaatattttt ttattatttc tacaagagca tttttctttt cttcattttc
    36541 tacagtgcaa gcttttccaa aaactatagc actagaataa gtagtactaa atttatctgg
    36601 aataacactt tcattagcaa ctactaaaaa agaaactttg ttgtttttcg atatattatc
    36661 taacttatgc ccatttcttg cacaatgaaa gtaaatagaa tcattaaagt atacataatt
    36721 tacagcaact ccataaggat aaccattttc agatatagtg gaaaaagtac caaattcacc
    36781 attttttaat acttcaacag tatcttcttt tgtcatttct ctttttttca atctcatttc
    36841 tttaaacata atatcatcct ttctaatttt gatgcttaaa ttaaatttta gaacatttat
    36901 aaagattatg caatgttttt tacaaatttt aagaaaaaaa tatagtttaa gataaaaggt
    36961 agtgaaagag aagctatttg gaggtttatt tatgatatta ttgttagagt agtataaaca
    37021 atactaataa atttaatagc tggtttcttg ttatttaagg tagtaagcat gtctataaga
    37081 aggggaagtt atcgagggta gaagttgtta tttataacga tattataaag aaaatattat
    37141 tatataaaat aataaatagt aaagaggtat caagttgaat ataatactta atacctcttc
    37201 aaaattaagt tataaaagtg ttgtgggaat tgtcctatac atggtaagga gataataaag
    37261 aatgtatctt taaagtctca actaaacagc aaaatttatc caacaaacat acaataaatg
    37321 cttctttgta tctaggtggc ttaacagtaa gtggccacat gtgttttaaa attatgtccg
    37381 tttctttttc atttatttga aaaaataaag ttgcattttt taatgcttct ctagggtgag
    37441 taaatccatg taatcctttt ctatcacctt tgtaatgcca atcataaaga aaaaagtcgt
    37501 gtagtaaagc tcctctaata acactttgaa tatcaacact taagtgcaat tttttacata
    37561 atagataact ataatatgct actgacaaac tatgttcaag acatgaaaca ttgccatgat
    37621 gaggaaatgt tctcataagt tgaacttttt cagaagaaag tatctcagaa gcacattcat
    37681 taaaatattt gatttcagct tttgacaaca ttatgaaaat ctccattctt agtaatatat
    37741 aaatactata cttcaacgat aatatgaaat atttcttatc ctacaaaata taatacccaa
    37801 taatacaagt aagatacctt ttatggtatt ttaaagtaag agagatttta ttaggctaaa
    37861 caatgaaaaa attaaaagta aagctatagc aatatatagt atttttccaa gaggattgcc
    37921 aaaatttata gtccatccaa taccaaacct tttattaacc attaatgatg ggtcatttgg
    37981 attattatac atgatgcctg ctatccaata cttctcatct tcttctggag aataagatga
    38041 gttgaatttt aaatttgggg aattaatata tgttgctatt aaataaatta taactaaaag
    38101 cgttgtaata ttcatagcag ttgatagttt tgtttttatt gataaaagag tagtaaaaaa
    38161 ctgtgttgtc attataatca tcaatattaa aaacaaataa ccaattttat ttaaatattt
    38221 aatgttttca actctacttt cttcaattct atttgtatct atcttaatcc ttgactttat
    38281 ggatccaatg gaagttatat ataataaaac cattaaacaa aagtcagtac cgattaattt
    38341 aaatacatta agaaatgatt tatctataaa aacatcagga gacccattta tgttccaatg
    38401 agtggcaatt gagtctggca attgattata attaaatgct ataaaaatac tcattcccaa
    38461 agtaaatagt atcggtatta aatagattat tttaaatttt tttattattt tatttttctt
    38521 atttataaaa tccatatcta ctattaattt tgaatctata tctatatgac ctaatttagc
    38581 ataaatttct aatttaagct tcttagcttt tttatgtgta tgaatatata gtatactttc
    38641 atataataaa aaacctataa taccaataaa ataggaaagt tccaatttat taaatgtaaa
    38701 aaccagaata aaaactaata taaagtctat aataaaacct aaagataata gttttttaaa
    38761 ttttttatct aactttataa agtaattata atttttatgc tcttggtcta tagaaactcc
    38821 atagatgtgt tttttaccta caaaataggg cataaaataa aatgtagcat acatcaaaat
    38881 tagaactgga aatattgtaa atagacattc aatcttactc ataatatttc acctcatact
    38941 tgtcaaataa acttgaactt agtgacaaaa attcttcttt actaatacct gataaataag
    39001 attttgccac caataattcc aagtcaagtt tatttttttg acgagttgta ttatctattt
    39061 tcattggtag ttgagctaca atagcacctt ttcttctatc aatatttaag aatccctctt
    39121 cttttaattc attgtaggat ttgttcactg tatgtaaatt tacaccaata ttttcagcca
    39181 tacttcttac agatggaagt gattcattta ttttcaattc tcctgaagct atagccttag
    39241 ttatttcttc tttaatttgt acataaatag atttatcact attaaaatct aaatttaaaa
    39301 ccataaaaaa cctccattat gctttataaa tgaaaacgat tgttatatac atagtataac
    39361 ataaaaaata ataacaaaca caaaatataa gtttatattt tgtaaaaatt gtaatttaaa
    39421 aaataacata atttttatta aaataataca gatactattt atagatagaa ataaaaatta
    39481 gaaaggagaa aaaatatgtt aacatattta atgaaaagac aaatgcataa aaaagatgat
    39541 ggaatgagta aaccaatgat gattacagga gctgtaatta caggtgtagg agcatatgct
    39601 gtatataaaa tggtaaaaag ccataaatct aattctcaaa tggtcaatac aaattattat
    39661 ggaaatagcg attatgatga ttataaatat gacgaatttg attatgactg tgattgtaga
    39721 gacacaaaac aagattatga atatgaagaa ttaaaaaaaa aagtaaaaga atttaattca
    39781 agaagaataa attgtgaaaa ttgtccacat gtttctcaag aagaaatgat gcaatatgta
    39841 aatagtgtta aagatgtaaa ggaagagatt gatttacatg aagatgctaa aaaagataat
    39901 atttacaaag aagatgaata caaaaaatat gaagaagaat aagtaatatt ttgtataact
    39961 gaacaaatag taatgtcaaa ttatttaata tctagtttta atatgtaagt tgtaacttaa
    40021 cttgaaagaa tcagtatcat tctttagata gttaagtaac aacttacatt ttatttttat
    40081 aaattttaat agttctttgt gactattttg taattttaga aatattttag tatccatggt
    40141 aattgtgtat aataaaactt gtatagatag atagtatgaa attaagcaga tagtttaaaa
    40201 ttaaaatgaa aagaaaggaa atagttatgt taaagttgtt gatagttgaa gatgacagta
    40261 ctatatcttt tggaataaag tatgctttag aacaagaagg atttagtata gatatatcaa
    40321 aggatttatc tagtggaaaa gaaatgattt cttctaatga atatagcatg atactgttgg
    40381 atgttacatt gccagatgga actggttatg agctttgtca atatataaga ggattctctc
    40441 aggttcctat aatattcttg actgcttgtg atgaagaagt aaatattgta atgggtctcg
    40501 atataggtgg agatgattat ataacaaaac cttttagaat tagagaatta atatccagaa
    40561 taaaagctgt tttaagaaga aaaggtaata cttcagaaga aaataagaaa atacttaaat
    40621 ttggagattt aagtatatat acattagaag ctagagtata taaaaatgat aaagaaatat
    40681 ttctgacatc agttgaatat aaacttcttt taattcttat acagaataaa aatactgttt
    40741 taagtagaac tcaaatattg gaaaaacttt gggatgtaac ttatgatttt gtaaacgaca
    40801 atactctaac tgtttatata aaaaggctta gagaaaaaat aggtgatgat ttatgtgaac
    40861 caatctacat agaaactgta agggggattg gttataaatg gataggaagt gaaaatagtg
    40921 tttctatata atccagaagt gaagaagttt ttaagtaagt atgttacttt gatgtttatt
    40981 gttatcataa tatctattgg atttagcata atcaacgtgt ccttaactaa agagatggtt
    41041 gtaagaaata atcaggctat aataggaact ttatcaagca agtatccaaa cttggaaagt
    41101 cagatagtag acataataac tcaagggaag tctatggaga acatagatta tggtcagaaa
    41161 atattaatta agtataatta tgataaatct attaggataa actctgagcc tattatttct
    41221 aaattagttt tagagactat caaaataaat ataatattag tatgtataat atttattttg
    41281 atatttgtgt tggttgttag atattttacg tcaatttaca atgatttatc agatatgact
    41341 aagtatgttt actatagttc agagggtaag ccatttgata tgaaaaacaa gaatcaagaa
    41401 gggcagatag gtcttctaaa aactgaactc ttaaagatga caacaattct taatgaaaag
    41461 gttgaacttt taaaaagaga aaagatattt ttaaacaata caatttccga tatatcacat
    41521 caattaaaaa ctcctatgac ttctttaata atgttgaatg atttattata taatgatgta
    41581 ccatacgaag taaaaatcga ttttttaaat aagataaaaa atcaattaaa tagaatggat
    41641 tggttgatta aaagcatgct taaattatca aaggtagaag caaaagtgat aaattttaaa
    41701 aaagataagg taaaatttag tgaactcata catagagcaa tgctatctat gaaaatacct
    41761 atggagatta aaaatcaaaa actgactata gagggaaatg ataatgtatc ttatattggt
    41821 gatattgatt ggtccgtgga agcattagtg aatataatca aaaattgtgt agaacatact
    41881 cctgaatttg gaaatataat tataacctat aaagaaaatc cattattttc tgaactaata
    41941 ataaaagatg agggtgaagg tatagataaa aaagatatac cacatgtatt taaacgattc
    42001 tatagaggaa gaagtagttc aaaagaagat agtgtaggaa taggtcttgc aatgtcaaaa
    42061 tctataatag aaagccaaaa tggcgatata tatgtaaaca gcgaaaaagg taagggtaca
    42121 gaatttcata taatatttca taaaatgtat gatagtgact aatctgtaat atttaattca
    42181 ctttatagta atagccaaaa cctaatatat gaagtataga atataaatat tggaggtagt
    42241 tatggaaatt ttaagagtag aaaatctaac taaaagttat ggtaaaaatg aaacaaaagt
    42301 tgatgctata aaaaatgtaa gtttatcagt tgaaaaagga acgtttatag caataacagg
    42361 tccaagtgga agtggtaaaa gtaccttatt acatttatta ggaggagttg acagaccaac
    42421 tagtggtaag gtttatataa atgatgttga tatatataat ttaaaaacta aggatttggc
    42481 gatatttaga agaagaaata taggtcttat atatcaattt tacaacttaa ttccagtctt
    42541 aaatgtgaag gaaaatatat tgcttccagc agagcttgac aatagagata ttgatagaga
    42601 atattttgat gatttaatga aaacattagg tctaattgat agagaaaagc accttccaaa
    42661 ccaattatca ggaggtcaac aacagagaac ctctatagga cgtgcattaa ttaatagacc
    42721 ttctataata ttagcagatg agccaacagg taatttagat agtaaaaatt caaaggaaat
    42781 attagaattg ttaaaattgt cagtaaaaaa atacaaccag acactaataa tgataactca
    42841 tgacaaaaat atggcacttc aagctgatag aattataagc atagaagatg gaatcataaa
    42901 aagtgatgag gtgatgtaga tgaatttata tacatcacta actattagat acttaaaaca
    42961 aaataaaaga agaaccattg taaccataat tggtataata ctttcaacag ctttaatttg
    43021 tggtatagga aatatatttg aaagttttat ggattatcaa atgagagaaa ctataaagaa
    43081 tgatggaagt ttccatgtta cattttatga tgtaaataga aaaaatgtgg aatatgtaac
    43141 gaaatcagct gaaatagaaa aacatgcatt taccaaacaa cttggatatt ctaaattaga
    43201 aaatagtgaa aatgctatat taagtataaa gcaatatgat aaaaatgcaa taaacggata
    43261 taaagtttct ataaaagaag gtagatttcc agctaaggaa ggagaaattg ttttaagtga
    43321 aagtattatt aatcttatag atgataagtt aaaaatagga gataagataa ctttaaaagt
    43381 aggggatatg tttgactcaa gcaagaaaaa gattgatagt atgacatttc atgaaggtga
    43441 ttatatagca aatgaaaaag atagaacttt taaagttgtt ggtataattg aaaaacctgg
    43501 gtttgaacgt tataatggaa ttgcaacagc tatagcctac tttaatccta tgaataatta
    43561 caatgataca attaatgtat cagtagcagt aagaaatcct aaagatgtgt ataagataag
    43621 taataaaata agtaaaaata tatattcaaa taaagataaa gaagcagttt ccgatatgat
    43681 aaaatacaat gaacatttat tgaggttaca aggtgctagt aagtattcaa atataaatag
    43741 ctctataaag tctataatta tagcagtaac tattttagta atcatatgta caattgctac
    43801 agtgtacaat tcctttagta tttctataaa tgaacgaaaa aaacagtttg ggatattaaa
    43861 ttctataggt gctacatcta gtcaaattaa aagattagtt tttatagaag gtattataat
    43921 tagtttaatt ggtataccaa taggactaat atctggaaca gtagctatag acctattgtt
    43981 taaaattata aataagtatt ttactgaatc ggttgttact aagatgagtt tgcagatagt
    44041 gtataatcca ataataatta ttgttagtat aataatagtt ttgcttacaa tctttatatc
    44101 aattctacta cctgcaatat cggcttctaa tatttctccc cttaatgtga ttaaaaatac
    44161 tggagagtat aaagtgggca aaatcaaaag ctcaagactt attaaaatga tttttaaaac
    44221 tgaaggagta cttgcatata aaaatattag gagaaataga aaaaaattta taataactct
    44281 tttttcttta atggtaagta taataatatt tatatctttt agtggcttta cattactttt
    44341 actaagaggt gaagaaatta gaaattctca aagaaaatat gatttgtatt taactgcaaa
    44401 gaacacagct aggtctgtag aggatactat aagtgaacta gaagatattg atgggataaa
    44461 aaactttgaa ttggcaacag gacaatatgt gtctataaga gtaagtgaaa ataaaataaa
    44521 taaatccaag gaagatttaa tcaggaaata ttatcaaaaa tataagattg gagatagtta
    44581 tgaatatgat ttcagtaata atgaattaat ttttccagga gattttgcag taaaaaacaa
    44641 aataaataac ttagtacagg gctcttttaa taaagagaga gcaattgaag aaaatggtgt
    44701 tatattagtt agaaaaagtg catttgaaga aaatgggaag aaaggtgtag tagaacttac
    44761 caactataaa gtaggagata cagtaaattg tgaatatctt gatgaaaatg ccttaagtaa
    44821 aaaagtaaag gtcaagattc ttgctataac tgatgaagaa cgtctaggtc ttggttatca
    44881 aaatatgggg ttacaattta taacttatga tgaagttgct aaaaatttaa atttaaaatt
    44941 aagtaaaagc cttatattta ttgattcagg aggaagcatt aagactaaga aggaaataga
    45001 agctttggca aataaaaata attttaactt ttatgatgaa agtgcaagca atgaaagtga
    45061 aaaacaagat ttaaaggtta ttaaaatatt tgtatatggt tttatagtag tgatatcttt
    45121 agtgagtgtt acaaatattc taaatacagt aagtacaagt ataaatctaa gaaaaagaga
    45181 acttgcagta atacaatcta taggggttac tcctaaagga tttaggaaaa tgatatattt
    45241 agaaagtttt atatatggta tactgtcatt gttgtttgga ataccaatta gtattggtat
    45301 aattctaatt atgaataaac ttatttcagg tgtaattgaa ttttctccga ttataccgtg
    45361 gacagccata gttatctgta tagtaagtgt ttttataata acttttatag cagggtatat
    45421 accaatgagt aaattaaata aagaaaatat aatagataat ataagaagag aaagtatata
    45481 gatataaaaa taattcttaa ctatataaaa tattattaaa atcatttaag tggtataaaa
    45541 tattattata tcacttaaat gattttttat ttatataaga aatctaataa taaattacta
    45601 gaggtattta actatttaga aagaattggt attatataaa gtaagagaat atataataag
    45661 aaagaatatt tgattttatt ggaaaacaaa agaaaaagaa ggtgattact atttctcata
    45721 taactgcgaa gaatatgtat aaaagtttag aggaaagaat aaacaagttt ccacaaggtg
    45781 ctccaccatc tgatacatta tacaaaatac taaatgtact atatacagaa caagaggcga
    45841 agttagttgc tcagcttcca ataaagcctt tcagagtaaa aacagcagct aaaatttgga
    45901 gtgtaagtga aagtgaagca tatagagtat tggataaact tgctagtaag gctctgatac
    45961 tagatataga agataataaa gggaagaaat atataatgcc tcctccaatg gctggttttt
    46021 ttgagtttgc catgatgaga acgagacacg atatagacca aaaacttttg gcagagcttt
    46081 actatcaata tatgaatgta gaagaagatt ttatcaaaga tttattttat tcaacagaaa
    46141 cgaagcttgg aagagtatac gttcaagagg aagttttaac taatgataat gaggttagta
    46201 ttttagatta tgaaagggct actcatataa ttgatgaatc aactcatata ggtataagta
    46261 tgtgttactg tagacataga atgcaacatg ttggaaaagc ttgtgatgct cccatggata
    46321 tatgtatgac gtttgacaat gtagcaaatt ctttaataaa taataaattt gcaagacgtg
    46381 tggataaaat agaatgtaaa gaactacttc atcaagcata tgaacataac ttagttcaat
    46441 gtggagaaaa tgttaggaaa ggggttacgt ttatatgtaa ttgctgtgga tgttgctgtg
    46501 aagcaatggt agcagctaaa agatttggaa atcttcatcc agtacagaca acaagtttta
    46561 taccaaatat aaaccatgaa aattgtgtaa agtgtggtaa atgtataact gcatgtccaa
    46621 tagatgcgat aagcaaggtt aaggaagatg gtaaagaata tataaaaatt gatgaggata
    46681 gatgtctagg ttgtggagtt tgtgttagaa attgccataa aaatagcatt atgttattaa
    46741 agagagatga aaaaataata actccagcaa attcagtaca tagagcagtt cttatggcaa
    46801 ttgaaaaagg gcagttacaa aatttaattt ttgataataa tgctctggct agtcatagag
    46861 ctatgggagc tatactgtca gctatattaa agcttgaacc agctaaaaag attttagcca
    46921 gtaaacaatt aaagtcagta tatttagata aattgttaag tattaatgat aaatagaaac
    46981 taacttaaaa aaggcaaagt tttagactta tctatatctt aataaactta tcatttaata
    47041 tttaaattta atttttacac atataaaact tataacttaa ataaaaaaag gctatattca
    47101 attaatatta cttgaataca gcctttttta gttatgttaa gctatttctt ttatttgctt
    47161 aaatgagttt tcatttccat ttccaccaat ttgtgttaca gatttaaatc tcatagtttt
    47221 aaatagttct ttttgattat aatctagtga gtttcctact agcattacag gagatttagt
    47281 ttttccagcc aaaactccaa cagataatcc gtctattaaa tcatcttgtt tattcattcc
    47341 atttttagca acatataaat tgtctatctt agaatccttg taaaattctt ttattacttt
    47401 tgcattagtt tcatttctag tgctacctga tattctctgt ggattttgaa gtttactttc
    47461 tatattttta gaaactgtat attctccacc gattacataa gatttatcaa tctttttgtt
    47521 tttaaatacg ttatttattt cagttatatt actattttca ttagtaagta ttataggcat
    47581 atcattttga gctgatacag ctccaatgct tactgcatcg gctaatcctt tttcgccatt
    47641 aactactgaa atctttgata tattgctaat attgttcaat tctttagcaa tgttcataga
    47701 agtttgatat ctatcacttc ctgaaattct agatacagag atattgtttg attttatagt
    47761 atctaaagat ttttcattta tagaagcttc tccaccaact acatatacat ttttaacttt
    47821 taatctcttt aattcagcca aagttttttc atttatttga gagcttccag tcaataatat
    47881 aggagcgttt ttcttgtatg caaatggtgt tgcagccaaa gcatctgcaa ttgctgaatc
    47941 gtttattaaa actgcatttt cagcattttc ccaacctgct tgacttatct taatagaagt
    48001 ttcatatcta tcagttcctg taagtgcact tgcatttact tcatcttgat atgtaacctc
    48061 aaatctagca tttggacttc ctaagaaaac aattacgcct ccttttggca atctaactct
    48121 attgttcttt gtaactaaag aatagtttac aggaacacct ttatcatcat aaacagcaaa
    48181 agctgaattt tgaggaagat taacttctat ttttttattt gcgatatcgt caccaatctt
    48241 ataccatttt gcataaccat tggattctag ttcacaagta aaagattttt ctgctggcaa
    48301 attagttata gaatcttcac taacatacgt tagtgttcca aaagataaat actctgtacc
    48361 attttcttta tgaagtttaa tgtcggataa atcacgacct attacaccag gtatttctat
    48421 aaaagcattt gagttattct catccattat tttagtgtta actatataac ctggagtttc
    48481 atcagaaaga ctaaaacttg cttttacaga gccaaacata tagctttgag aagtatattt
    48541 ttcatccact agatagtaac ctttgccact tctttttttc cacacttctt tgacactatt
    48601 tgatatattg ttgtcatcta ctttttgagc tacatagtat aaacttgctg tctgacctaa
    48661 tccagggaca tcatcataag agctcatatt taaatatgtg atattatttt tttcttttac
    48721 aaattttaaa caactattac ctttttcaga tacaaatcta tcttgaccta tgtatacgta
    48781 tttatcttca ggtccatttt ctatataagg agaagatact gttaaagtac cattatcatt
    48841 aacatctact tttatcatat ttgaagaagc ataaagacca ctattttctt ttaaagagct
    48901 tggcatttta acttgttgtg gcttactaaa tgttttatca ggttttattt ctttaatttt
    48961 acctttttct tttaatgcag atagtaagat ttcttgtcca attatttcat taagttgact
    49021 acttccacca gaagaaagaa ctgcaactgc catattttca tctggaagaa ctataagatt
    49081 actgtggaat aataaagaat ctccaccttt tgtaagagct tttaaattat actgattaaa
    49141 tggataagtg ttgacacaat cccaccctaa accatatcca agtatagagt cttctccttc
    49201 aggccataga ccatttaaat attctttgtt ttccatagct tttactgaag caggagaaag
    49261 aataccattt gaatttttca taaatgtttg tgcaaatgta catagatttt ctgcacttga
    49321 atataaacca cctgcaccta tagcattaag gttatcttgt ggaactgcat cttcccaata
    49381 aggtacgtat gcttttgcta gttttgaact atcaaagcta ttttctgtag tttttgtatt
    49441 ttgtaagtta agtggattat ttatgtattt atcaagaaaa ttagtaaatg acataccaga
    49501 tactctttct actaaaattt cagctaaagt aaatccatca ttacaataaa cggaaaaagc
    49561 tcctggttta gcttttaatc tttgtttttg taattctttt aagaaattat catgaccata
    49621 agaatcattg tctgctaata aaatagtgtt tttaaaacta cttcccatca accctgatga
    49681 atgatttaat aacattcttg gagtgatttc cttgtatcta tcatcagcca ttttaaattc
    49741 aggtatatac tttacaacag gagtatctaa atttaatttt ccatcatcaa ccaacttcat
    49801 aacagctgtt gtagtaaaca ttttactgat agatgcgata ctatacatat tatccttatt
    49861 taagtttttg ttatcctgtt tgctgtaaac tccaccatta ccagaaatct caattttgcc
    49921 attatcaatc aaagcatatt gagcacttac agcaccatac tttgatagca aagtttggat
    49981 tttctcttta gcaagagctt tagtttttgt gtaagattcc gcgtttttac tataatcatg
    50041 taattctata tcagaacttt gatatttttc ggaattatct tttgtattat cagcaaaagt
    50101 aatatttgga gcagcagtaa ataacatact caatactaat gtactagata ataatttaga
    50161 gagcctttgc ttaaacatat tacattacct ctttcccttt ttaataattt ataattagca
    50221 taacattctt aattatttta atcaacagat tattatcaat aaaaaaagct tttataagta
    50281 tagcttttta tataacagag aaaaatataa aaataatatt tgttgttgta taaagaataa
    50341 agggtatagg taatatataa ataaaatgga ggaattttag acatatgtat aagaatataa
    50401 ataagaagca acttaaagaa atgatgaaaa atgaaaagga tgttttatta ttagatgtaa
    50461 gaactaaaga tgaatttaag gaatataaaa tagaaaatgc tataaatata tctttacaag
    50521 agttaatcaa taatatagat gaaatttacg attataaaga taagaaagta gtagtttatt
    50581 gcagaagtgg tcatagaagt gttactgcat gtaatttgtt agctgaagaa ggttttgagc
    50641 atttatataa tttaaattca ggaataattg attatatgag ttaaataatg taagttatac
    50701 attaaatact atgtatagct ctgcttatta agtaggaata tatctaaata tttataagat
    50761 aaatttagga aagaacgaat tttttcgttt ttttctatga cagtttttgt agtaaatatt
    50821 agtttttaag ttggaaaaag gtagtagctt tttagctact accttttaat atgaacttag
    50881 aatattatta aaaaaatata tttaaagaca gaattaattt tttaatgacc agttaaatta
    50941 ctatcgccaa atttatcatt aaatggtttt ataactctat ttataggtcc ttttagaagt
    51001 acatttaaac aaatagacag aatcataaat agtaatagaa ctagtatatc tttagttaga
    51061 tttggagcat atataccacc aactgcttcc cttgtagcac ctattgcata ggtaaatggc
    51121 attatagggt ttattctttg gaagaatgta ggtgtaactt gtatagggaa tgtaccacca
    51181 gaagaaccaa tctgaacgac taatagtact attgcaattg cttttcctac atttccaaat
    51241 acagaaacta aagaatacac tataaagtta aataccatac tagtaaacat aagcagaact
    51301 atcaataaaa ttggatgttt tgctgttact cctaacaata atatatctcc agttcctatt
    51361 ataaaacctt ggacaagagc tatacttaaa aaagtaaggc ctcttccaaa gtaaatttca
    51421 taaggtttat agtttccatg tacagatgta gacaatagtg ctgaaataag taatatacca
    51481 acccatgtag aaagaacact ataaaatggt gtcattgcag aaccataatt ttcaattgga
    51541 tataatttct ctgttttcac ctcaacaggt tcttttaaga aattagactt tgtcaatata
    51601 tcactttcaa gcaagctgac taattttttc atatcttcac cattactaat tttgcttaaa
    51661 gtatcaatca aatcatccaa cattcctttt gctaaaggaa gtctttctct tatcaatgat
    51721 atactttcct gtgcatttcc tgaaagtttt agagaagtag taagtatttc ttcaaccttt
    51781 ggaagttttg cttctgcctt atctaaaaca gtaattatat catttgctac ttttatactg
    51841 tttgcaaata tactatttat aggttttgat atttttgagt caaaattatt taaaatattt
    51901 aaattaattc ttccaatacc atttgataga cttaaaacat tattcaaagc acttatagat
    51961 ggttgttgtc cagatataac tttgttttta atatcattta atgttgatat agatgaatct
    52021 attttattgc tagagtcttc aagattatct atgacatcat ccaatctatt atttgatgta
    52081 agttggttta atttagttaa aaaatccacc aaagtattat ttaaagattg caaattagaa
    52141 agtttttctg ataaattatc tatcaactta ggtacatctt cactgccact atttactgca
    52201 tcaattaaat ttaatgtaag agaagaagca gaagatgaaa ggtcaaccat taaatttaag
    52261 tcagacttaa taagaggaga aagttcgtct aaattatcat ttgtatcctc taagaatttt
    52321 tttaagtcac ttgataacag ttttgtatca ttcagagttt ttttaattgt aggtaaatca
    52381 gatttaatat ctttaactgt atcagataat tttgaagtag catcagaagc taaatcaaca
    52441 gtcttattta tatggtcaaa tctcttttga aggtcaataa gggaattttc aacttttgtc
    52501 aattttggaa gactgtgttc aattcctgca ccaactccgt ttgatatacc aagaacgatt
    52561 tcactaactg tttttactat agtctgatta acctgtagtt gtattgtaga agcaccttta
    52621 tctgtaatct ttggtgcaac tgcatttatt ttttcattaa cagtatagat aatttcccct
    52681 tttttaacat catctgtaat taaagatgtc aaatcttttg taaaattttt tggaatctta
    52741 agtgatgcat aataagtacc ttttttaaca ccttcaagag ccgttttttc atctacaaac
    52801 tgccaaccta aactcttgtt atctttgagt tgttcaatta attggtctcc tacattaatc
    52861 ttttgtcctg ctatttcatt tcctttatct tcatttgtta ctgctacaag catattagca
    52921 gtgcttccat aagggtccca agatgccttt atattgaacc aagcatacag agatggtaaa
    52981 aaagcaagac ctaaaactat tacaagtacg gcataattgc cacgtatatc ttttaggtca
    53041 cttttaaaaa tttctaatat attttttaaa ccctttgaag gtcttaaatt cttgatatta
    53101 ttccagttta aaatttcttt taaactatta gtttttttca aatgtctcac ctcctaaaat
    53161 attttgataa agaaaaaagt tagatttata atcaatttta aattatatta ctttttacac
    53221 aaatagtaaa gttaaaattt tgtcttaatt ttaatacat
//
LOCUS       DAMJXI010000021        52007 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.022, whole genome shotgun sequence.
ACCESSION   DAMJXI010000021 DAMJXI010000000
VERSION     DAMJXI010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 52007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52007
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.022"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(177..425)
                     /locus_tag="PC465_001645"
     CDS             complement(177..425)
                     /locus_tag="PC465_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2648962.1"
                     /translation="MQKTKAWGIIEPEKPESQQQMAHMDFAVNDLEEAVQYAIHCGAT
                     IAEEQFTDDWRVMIDPAGHPFCLCQMKSIMESSHFSLL"
     gene            complement(456..917)
                     /locus_tag="PC465_001646"
     CDS             complement(456..917)
                     /locus_tag="PC465_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HDF2648963.1"
                     /translation="MKFGGVLLIVKDINKSKKFYEDVMEQKITLDLGEHVSFENGFGL
                     QSNYKAIIGYDLPIYQQSNNFQLYFEVNDIKQWESKINRIGNIEFLHYIKEYPWGQRT
                     FRFYDFDKNIIEISESMESVIKRLLKQGLALEEISKRTMYPVEFITQFQQL"
     gene            complement(955..1788)
                     /locus_tag="PC465_001647"
     CDS             complement(955..1788)
                     /locus_tag="PC465_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2648964.1"
                     /translation="MLKKESIHFINKNRSLIVCEDNFVYLLPCIQLRNWISNFTISFP
                     NQTIISDNYTIIPHGSVTLVFFYDATGLHSLLFGPTTKPKTVGNIANRCDVILIIEFQ
                     PAGFFPLIGIQQSELIDKVVPFSIINTSLDLEIKKIFNESLSIDKLILKLEELLISNI
                     KIEYSYEFILAIQLIIQNSGNISSQEISKKVFYSSRHLNRLFNQYLGLSMKSFSRLVR
                     INKSIKLLNNNKTSLMSICNELGFYDIPHFIKDFKIVCGITPQKYRANMSDFYSEIAK
                     F"
     gene            complement(2062..2748)
                     /locus_tag="PC465_001648"
     CDS             complement(2062..2748)
                     /locus_tag="PC465_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2648965.1"
                     /translation="MKITHNSLAVEAKNIIKEYKIGNTTTRVLKEVSLQVMKGEFVSI
                     MGQSGSGKSTLLYILGGLDTPTSGKVYMNGADISHFNDEKMSIIRRRNIGFVFQFYNL
                     IPNLNVEENIMLPLLLDGKNLKDYKNQLDEILDIVGLTDRRKHTPRELSGGQQQRVAI
                     ARALIGKPEILFADEPTGNLDSKTGIEIIDLLNKINRDNGQTIIMVTHSPEAAKSSSR
                     TITVSDGLIV"
     gene            complement(2763..5240)
                     /locus_tag="PC465_001649"
     CDS             complement(2763..5240)
                     /locus_tag="PC465_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2648966.1"
                     /translation="MKIILKYIFTNIKERKIRTAVMLLSIVLSTVLLFVSFSIGLSYE
                     SAQRKMAKGMYGTATISVQSKNPDILTNLEDIPDLNAIKSKVGVLESSAIYNKGGYYE
                     EFSLISADLSQLNKINKPRLENGDSITDFSGDKIILPNRFTSKYKIKKGDSITLQIYG
                     KSYTFQVSDIASYDTVFLRNTRGVNALLPKETLSKIINKGSGYTRILIESEEEITENL
                     VNKLSKELSTEKYMVSNTINETKIISDARQKTMPFFLISFFALTLSIFIIYSSYKVIT
                     LERLPFIGTFRSIGANEKTVTRILMLESILYGSIGGLIAIPIGVVVLNLMLHGLGNSL
                     EQGISIPVVISPIGVIISVIVAIIVSSFSAYIPVKKASHLPIKNIVLGTVEEKNVSNR
                     SILFIGSIMFILSILLPRISPENTLYLAGGFSLLGLIVATIVLIPLITDIMSIVFEFV
                     YKNILGNEGKLAARNMKNNKNIIQNITLLFISISAVIAISVVGNFVKTYITDVFRDAE
                     LQGFADGKMNEEFIEDVRHMDGIKKILPLYVMNNEISGNGVTLSRLEGTDNIKLYNSM
                     FGINYTNFEIKKQVIEAFNDKRSVILNEDTLKKVGLSIGDTITLSNDKYDFSYKIVGS
                     FKSRANDVEAVIPSHYAVNDFDKTNYGFLVYTAVNPDAVMIQIRYLFGDTYNWSRTVE
                     EFNNDSLNTISSFLSPMNKMTYFIFLLATVGIINNLLINYIQKRRSIAMYKSIGLSDK
                     QNIKVTLIEGFTSGLLGAVIGIVISILEIQTIFIVAGPKISMKPDLDFKTFIIVGLLG
                     IIVTLIGSIVPIIKGKKMKLIEEIKFE"
     gene            complement(5459..6862)
                     /locus_tag="PC465_001650"
     CDS             complement(5459..6862)
                     /locus_tag="PC465_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2648967.1"
                     /translation="MHKPSYKTVFHSYIIFFMIFICLILTVIGIFLSLITIQKPNGEF
                     IRSDWPKKFTENFNEQIVFIDNKPQVKQSGLKKLRENQLWLQILDSSGNRVYGFLEPK
                     EHKDYYSNSELLALANQNNSSNGTVYFNTIKNNKNDYIYIIYFPLNISKVNMFFDGGK
                     FIGGKSIIFSIIGIIFLIILVSGIAYGYWVTKCISNITSAVSDISKRSYLPVNIKGVF
                     ADIYNSLNILNEEIHKSDEIQNKTDIMREEWISNITHDLKTPLSPIKGYAELLTDSST
                     NYSPEKVHKYASIMLKNIEYTNTLINDLKLTYQLKNGIIPLNKNNYDLVRFLKELSID
                     ILNYPEYESNIVEFKSNIDNINFDFDCTLLKRAFSNLIVNAFTYGDKNTKVCVHITLN
                     ERIEIIISDNGKGMSREEASNLFNRYYRGSNTKQKIEGTGLGLAITKQIIEVHGGNIS
                     VESIPGLGSSFYITFPI"
     gene            7356..8216
                     /locus_tag="PC465_001651"
     CDS             7356..8216
                     /locus_tag="PC465_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2648968.1"
                     /translation="MKKQKSPILLEMLGLFFGCISMSIGINMFLKPHTIAPGGLSGLS
                     LVLNKVTGLPVSAIMLIIGVPLVILAFRIMGTKNSLKTLFGTVVFSAIVQLTDPLSKL
                     RFTNDLLLSSIAGGILVGIGLGIMFKSDASTGGTDLIALILSKKFPGIKATKFMSCLD
                     GMVVISSGIVNRSLETALYSGIALCVLIKIADMIMEGFDHSKAFFIISDEPESLRQAI
                     TEELDRGLTILDGKGGYTRENKEVLLVVVSKKQELYLKRLVKRTDPTAFVIVTDVHEV
                     LGEGFKNLEN"
     gene            complement(8455..9012)
                     /locus_tag="PC465_001652"
     CDS             complement(8455..9012)
                     /locus_tag="PC465_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2648969.1"
                     /translation="MSDSEYPQMKTLETRSCILRPASLDDVEDFFDCYKNKIVVKHLP
                     FSEHKSLEDTRKFIKSFFLNPYKKGKIGHFAIVYKRDNKVIGNMGFNNINPKALEAEI
                     GICINPSYWGHDFATEITKRVIQYGFRELNLNKIIAITYEENQNSTKSLDLLGFKCTG
                     KYIKKIHTGNTVKNVPCYQYELKKQ"
     gene            complement(9202..10089)
                     /locus_tag="PC465_001653"
     CDS             complement(9202..10089)
                     /locus_tag="PC465_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2648970.1"
                     /translation="MNIKLELYKVFNAVVNNKSFSLAAKELFMSQPAVSQSIKQLEEQ
                     LDTLLFYRNNKGVKLTPEGKILSEHVTTALKLISSGEDRINKFKKLEYGSLKIGVGNT
                     AARFFLLKYLEIFHKKYPHIHVSTINRTSRELISLLKDGNIDIAIINMPIEDDTLNIV
                     ECIEIHDIFVCANDYIEYKGRKISLEELNTLPLIMLENKANSRLYVNEYFLSKGIKLN
                     PDIELGSHELLLEFAYINLGVSCVIEEFSIDYLENEKLFKLDIKEPIPKRNIGYCHLK
                     DISLSLATKEFLSMISNNI"
     gene            10208..11407
                     /locus_tag="PC465_001654"
     CDS             10208..11407
                     /locus_tag="PC465_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003493023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HDF2648971.1"
                     /translation="MDRLVGTVSRGVRAPIIRQGDDLVKIVVDSVLNASKSENFEVRD
                     KDVIAVTEAVVARAQGNYAHVDNIAKDVKDKFGDDTVGVIFPILSRNRFAICLKGIAK
                     GCRKVVLMLSYPSDEVGNHLISIDELDDKGINPWSDVLTEEKYRELFGYNKHTFTGVD
                     YVDYYKNLIKDCGAEVEIVFANNPKTILNYTTSILTCDIHTRQRTKRILRQNGAKKVY
                     SLDDIMTASVDGSGYNDQYGLLGSNKATEETVKLFPINCDEVVNKIQGNIKEITGKDV
                     EVMVYGDGAFKDPVGKIWELADPVVSPAYTKGLEGTPNEVKLKYLADNDFADLSGDEL
                     KEAISKYIVEKDNKSDDLTGNMVSQGTTPRRLTDLIGSLADLTSGSGDKGTPIIYIQG
                     YFDNYTK"
     gene            complement(11601..14156)
                     /locus_tag="PC465_001655"
     CDS             complement(11601..14156)
                     /locus_tag="PC465_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2648972.1"
                     /translation="MMSLVKFSIQYIKHYKKQSISIVLSIVLSVALLTGIGSLVHSAD
                     KSRIEKIREDSGDYHYFYKVDKEQLNKIKENKKSKEYTVDRLGVTKPKNQIDEPFIIE
                     FLNADSSYLDMTGRKLLKGTLPSKDGEIVLDTYSLNNLNVNKEIGTEINLDGKIYKLC
                     GILSSLSNPETALEGFVNDYFQPKEKDSYIVYVKYDENKNIKKQNYKFMKKFNISKEK
                     TYINWPLSVEFGVKPPKNIEKYNIFEFLKNLELNTNAIILLVGVFGAAAVYSIFHVSI
                     LQRISQYGVLEVLGANNKQLLFLLFLELFLLFIVGFPIGCFLGIGVASTIYEQFPHIF
                     LSSDIVPGAFFISEKSIYLGFLFILLLLILIAVRVVHQLNKYSSIESMKNFKITNKKK
                     RILESVKHSNMTKVLSHKYMTQKKGMFIGILFSLSLGGIIFLCSSYSIQLTKNNNELT
                     MKADDGLNSDYQITMQTTDFDVGIPKDKISRLNNVEGISKVYPVRYLFGAMQIKEEQL
                     FWKNFFKPLEKDYRIKTFFDGICTKQNEGGYLLKTNIYGYNNGMLEGLNSYIIDGEIN
                     THDMVKNNKVIVRLPMDGTGMYDAVDINPGDTIKVKVPKTMKPTDEIVKFKEENKNDY
                     TTKEFVVAATVKRVMANNIYFIGDYGMDIVMTNGQMKNNFDIENYNSVSIKKTEDSNS
                     EELSENIKSVVSDVKRCIVTDYTIAIEKNNTYLNQKLLFIYGIVFVLLAISLFHIINT
                     VSYLIFSRRHEFGILRAMGITDNKFLLMMIREGFLYGFYASIIMVIGSVIGQFMIYFM
                     VKRVYLYINPILKINTPLYIGMIILNITISIVAVIIPVRQILKSDIISEINKN"
     gene            complement(14153..14839)
                     /locus_tag="PC465_001656"
     CDS             complement(14153..14839)
                     /locus_tag="PC465_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2648973.1"
                     /translation="MSILVTNNLVKHYGKGETKVKALNGVSIEIERDTFTAIVGTSGS
                     GKSTLLNIIGGLDNPTSGDVIIKGKNISKIGKKDLTVFRRRNIGFIFQNYSLMPVLNT
                     YDNIALPVTLDKGNHIDHEYIEMLMKTLGIWDKRLKFPSELSGGQQQRVAIARALANK
                     PALILADEPTGNLDSKTTMEVVCLLKESSAKFHQTILMVTHNENIAQVCDSIIHIEDG
                     IVVNTGGEVL"
     gene            complement(14916..15824)
                     /locus_tag="PC465_001657"
     CDS             complement(14916..15824)
                     /locus_tag="PC465_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2648974.1"
                     /translation="MFILAFIICTVVIFIVSTKINQRRYDELNLMLNQILEGKEVTYP
                     DTKDTRASKISHQVKKIKDMIEIEVEQSKSEKEAIKGLISNMSHQLKTPLSNITIYCE
                     LLENINISTLQKKEFLQKMKNETFKIDWLLQSLFKMTKLEDGVIEFEVEELLIKDTLI
                     QSISTIFNKAEAKNIRINLEPFSDIKLVHNKKWTIEAIVNVLENAIKYSPSDSTITIS
                     VIKMELYTKITIKDEGIGIDSRELNDIFKRFYRSKNVENQNGTGIGLYLTRLILEKEN
                     GNIIVESKLGSGCCFSIFLQNCKSLN"
     gene            complement(15826..16497)
                     /locus_tag="PC465_001658"
     CDS             complement(15826..16497)
                     /locus_tag="PC465_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2648975.1"
                     /translation="MNLLIIEDDINLNEGLFYAFENDGFNVFKAYTKQEGLNIFNSKN
                     IDFIILDCNLPDGDGFDVCQIIREKSDIPIIMLTARDSEIDEVKGLEIGLDDYITKPF
                     SLSVLKARVKVAIRKKSNNKVIYSNGIKLDQKLLKVYKNKECLELSSVEYKLLSYLIE
                     NKGQILLKEQILHHIWDSEENYVDDNIVSVNIRRLRVKVEDDPSNPKYIKTAYGMGYL
                     WNEVE"
     gene            16759..17823
                     /locus_tag="PC465_001659"
     CDS             16759..17823
                     /locus_tag="PC465_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S ferredoxin"
                     /protein_id="HDF2648976.1"
                     /translation="MKRVDERNTMFARANYKKDSTAYNDYYKKNPDKKEIDDSIRNRP
                     NLCSEGTMTYNELNSPMASSAFDFLSDIKSLCEGKVSDTKVDVDAKSMTKKIKGLAKQ
                     YGASVVGITKLKDYHIYTNRGRHEENYGEEINLTHKYAIVFGCEMDKEMINRAPMICE
                     VIETSKCYVDASIVGMILSYYIRNLGYDARNHMDANYLVMPVFIARDAGLGDIGRNAI
                     LTNKDYGSRLRLGVVTTDIPLLEDEYVDFGLEDFCKVCKKCSFNCPSHSLSNDIKIGD
                     DGKYNWVIEHETCYIKWRYLGTDCGMCISACPFSQNLETIKNTTSFKGNNELIQKALD
                     EYTSKFGKRIFIPGNPSWLK"
     gene            17981..18667
                     /locus_tag="PC465_001660"
     CDS             17981..18667
                     /locus_tag="PC465_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2648977.1"
                     /translation="MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFEC
                     EFDLIILDINLPDKSGFELCNEIKENYNIPIIFLTANDMECDMIKGYELGALDYITKP
                     FNINIFKQKVKAFLNHLTVKTKQDYYRDGYLEINFSELSANINGNQIIFTPLEYRTLK
                     LLTENPKSILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMG
                     YMWLGERNEF"
     gene            18657..19688
                     /locus_tag="PC465_001661"
     CDS             18657..19688
                     /locus_tag="PC465_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2648978.1"
                     /translation="MNFKKFSFSSIYLIIAVGIIFTAILFSISIYLITDDLKLIALLL
                     IYTIVLCGFIALTIFLLHKKIVIFCSKICHTLDSMMNSEDNIEIELEEETILSRINHR
                     LIRMYEVIQENRNSIAIEKADLQELVSDISHQIKTPIANLKMINTTLLNQTFKTEIQK
                     DFLMDMENQLDKLDFLMQSMVKTSRLETGIITLSKKKNSIYETIATALSGILFDAEKK
                     NIEVTVDCDPNLYIIHDKKWTSEAIFNILDNAVKYTNSNGKIHVATECWVMYTKIDII
                     DNGKGISESHQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQGGYIKVTSDIGKGS
                     TFSIFLPNK"
     gene            19770..20435
                     /locus_tag="PC465_001662"
     CDS             19770..20435
                     /locus_tag="PC465_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2648979.1"
                     /translation="MSILQVINLKKYYGQSSNITKALDGVTLSIEKGEFISIVGTSGS
                     GKSTLLNMMGGLDNPTSGKVIIKGKELSTMTDEQLTIFRRRNIGFIFQNYNLVPLLNV
                     YENIILPIGLDGETIDKDFINEIINMLSLEEKLYDMPSNLSGGQQQRVAIARALVTKP
                     AIILADEPTGNLDSRTSSDVLSLLKVTSKKFNQTIVMITHNNEIAQLTDRIIRIEDGK
                     IVN"
     gene            20448..22865
                     /locus_tag="PC465_001663"
     CDS             20448..22865
                     /locus_tag="PC465_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2648980.1"
                     /translation="MFRNNNRTFIRKIALNDLKINKLKTYLSGIIIMISTCLLLTVTL
                     VSYNASVDLVNASPYHAIYKSVDEKAKNILYKDKNFSGVGTYKLIGSNKKTDCIMSIV
                     YADDTAIKLMNFQPLKGKLPTNKNEIAISEKYLQEFGLDKDIGDSIKLNYYDDITNKE
                     VQCDFIIVGFLENYYQDNAKQYYTVVSNDYFKNIASTPLQNKSNTFDESRPDTVDVLV
                     KLSEENTEKDSASIKTQLKKIGLSLGIKKYNIYLNDNYIESNLIDGEQIITVLVVGIV
                     VLFSSVFVIYSIFYISVVNSVQMYAKLKSLGMTSFQLKKIISLQGNILSIIFIPLGVI
                     ASCIIAYIIQPLAWQMIADLFIILILSLVMFLTVRISLFKPARIISKISAIEAMQYTE
                     TKFRKKAKNFSYINIKNLALKNIESNRKKNLIALISLSISGVLFISIANLANSIDFKK
                     QLSQQFVYNEDYIISIKSDNLYEHITEIQQNNPLTDSLKNEIKSIHGVKKLIESKSIK
                     SNIIEPYIKDRDEKQFITLIKGITPELSKSLEEYIVSGKIDYTHLDSDSLIINKYRTK
                     YYGLNLKVGDTVTFNIFSGNDIIKKKMKIIGIIDNSNTGGMFFASDKTLESLTPYNTN
                     LDFSILIDKKHSKEVEEKLLSIIQKNSNLMLYSYEDDYRMITRAFQYIIIASYIFVGL
                     ISCFGILNMTNTLINSVLIRKKEFALLQAVGMTRKQLRNMLYREGLNISIKAICTSSI
                     LGYFGSNLLCTFIKDVIRLDFINFKFSIFTILIFSFVLIGIQVLVTELLVRNIEKKSL
                     TERLRSQ"
     gene            complement(23046..23837)
                     /locus_tag="PC465_001664"
     CDS             complement(23046..23837)
                     /locus_tag="PC465_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2648981.1"
                     /translation="METKQYLIDFYNTYDEDSRLALKHGMVEFLTTMHYIDKYIKSGD
                     CVLEIGAATGRYSHTLARQGYDVDAVELVEHNIEVFHKNTQSNENISITQGNAMDLSV
                     FPDNKYDITLLLGPLYHLYNKEDKQQALHEAIRVTKPGGVVFAAYVISDGCLIDEGFH
                     RGNINVSEYIEKGLIDPQTFAAKSEPKDLFELVRKENIDDLMSAFNVTRLHYVASDGL
                     ALYMREAVDSMDDDAFALYLKYHLATCEREDLVGVTSHAIDIFRK"
     gene            complement(23870..24457)
                     /locus_tag="PC465_001665"
     CDS             complement(23870..24457)
                     /locus_tag="PC465_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2648982.1"
                     /translation="MPPKVKITKEMILNTVLDITREVGFEAVNARSIASKLQCSTRPI
                     FTCYENMNELKNEFLAFAYEYYNQYVVNYRNSKSVSPYLLLPLSYIEFAQEETYLFKL
                     LFINDLDLMMKEANDFYKEIYNEKKARLFSESIGIDLECAKVIFLDLFLYTHGIAVLT
                     ATKKLTLDRYSAEKMLKNILTAFIRQEKPDWNLSI"
     gene            complement(24634..26025)
                     /locus_tag="PC465_001666"
     CDS             complement(24634..26025)
                     /locus_tag="PC465_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate/H(+) symporter BenE family transporter"
                     /protein_id="HDF2648983.1"
                     /translation="MERLARREQPHIKFGMFKIRIPFIHYRFEKPEAIQGIISSMTSL
                     GTIGLSTQILGLPYEVAWSMAIINSILYCLHVFMGDPVVPGWITASITLTTAYLLKFS
                     MGIERIQALTALQIDLGIIFILMGITGVAGKLVSKIPNSIKGGILMGVGISTIISEFN
                     PKGRFDSYPISITVGILVACFVMFSERFDTLKVKNKFLFHLGEYGVVSAILVSLIVGI
                     FSKEIEIPRFSFDNLVYIVDFKNLINTVSPFGIGFPSVMLFIQGIPMAFMIYIIAFGD
                     FITGENLVLSESENRKDEYIDFNSNRSNVISGIRNIFMAIFSPYIPMCGPLAATLTGS
                     VAQRYKVGKEAMQSVFSGMGTLVWVSAIFICFYPIAQIATPLIPLALSVTLLVQGYLC
                     TKLSMELCNTGVEKGLIGLMGGVIAAKGGTWGLAVGFILYFILIDSKKRKEKDINSIE
                     DCVYEILDKKKSI"
     gene            complement(26215..27513)
                     /locus_tag="PC465_001667"
     CDS             complement(26215..27513)
                     /locus_tag="PC465_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase/BAAT N-terminal
                     domain-containing protein"
                     /protein_id="HDF2648984.1"
                     /translation="MKVNVYNVESFVDERLKIMVSDLIQNTKLKISVKMEFPWCKGEE
                     FSSYGVFCSNEKGEVDLDLVEPIEGTYKADNCMGLIYSLEKSKTEGKNFAENISIDKP
                     IIMNMIFETSIERKEVELKRIFKSEDITTKYISDEFIGKLFYKQNSNNKTILMLGGSD
                     GNLDALDLLAAPLASRGFNVLTVAYFALEGLPDKLEEVPLEYFEKVFEWISENEITST
                     KEIFVHGTSKGGELAFLLASRYEQIKKVVVSQPHIYCFQALNGLMSGNDTSSWSYKGE
                     PFPYIKVDNDIFFEEQKKNISKGIPFGFNSTYKKSLKRAENRKEARIKIENSKADILM
                     IAGKEDNIWNSYEACLKALEIFEENNYPYNVELLTYNNMGHPLPIPYIMPLKETLCMS
                     MSGGIFSSGGTVEGNSKGQFESWNRTIEFYKKPLSSDLNN"
     gene            complement(27872..28747)
                     /locus_tag="PC465_001668"
     CDS             complement(27872..28747)
                     /locus_tag="PC465_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HDF2648985.1"
                     /translation="MITFDVNGAIIRFDDTKNNYNKIRKIFKLYALEISKNFERDCLN
                     SFQNLKQISDRGLSLGEKYIEESFKKGIETIVSFGIITIDIDTFKSVYCEKYLDFKRL
                     FNNLNKTFIIPNKNKKNGHASFLEIESTIKKMSNYLYNDCFKIHYAVVDALIENRITA
                     VHSYIDEESIKKSNALFNNYKDGFIGKADECKVVKQIITLNPYREDVYEFLVKEDGDF
                     SKEIERLTEFLGYDIREYKASLMDIYINELMESDENDVENAKEKIEKYARYIGCSDEN
                     LYVARVNAIYTFANA"
     gene            complement(28940..29626)
                     /locus_tag="PC465_001669"
     CDS             complement(28940..29626)
                     /locus_tag="PC465_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HDF2648986.1"
                     /translation="MFGVIANSLAIAGGCIVGLIIKGGLPQRVSDTIMNGIALCVLYI
                     GISGALEGKNTLVTIISVAVGALIGELIDIDKWVNKLGAFLQSKFSKGNKKDSIAEGF
                     ISSSLLFCIGAMAVVGSLESGLTGSHDTLFVKSVIDGIASIIFTASLGIGVMFSAISV
                     FLYEGIICVGASFLNGFLSDPVVTEMTAAGSLLIIGLGLNVLKLTNIKVANLLPAIFI
                     PILFGVFGII"
     gene            complement(29675..30208)
                     /locus_tag="PC465_001670"
     CDS             complement(29675..30208)
                     /locus_tag="PC465_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HDF2648987.1"
                     /translation="MSDLNNKKEQDENESSMNETKIYDILDKLNVEYDVVEHEAVYTA
                     EQLVILDGITKGCQCKNLFLRNAKGNKYYLIVVKGEKQVDLNSLKDKIGSSRLSFASP
                     ERLYNVLKLLPGSVNPFSLINDTERKVELYIDKDVIKEDYLNFHPNINTKTVNISRKG
                     FEEFLEYLKYPIQSIDV"
     gene            complement(30252..30884)
                     /locus_tag="PC465_001671"
     CDS             complement(30252..30884)
                     /locus_tag="PC465_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HDF2648988.1"
                     /translation="MKVFDLTHVTHNDMPVYAEPNRPDIKKVAIIEENGYQETLISVF
                     SHNGTHMDSPRHMYTKGETLDKLDIENFVGKAYVLELEKGNENIELEYLKKYEDEIKN
                     SDFIIFKSGWSKFWDKKQYYVGYPTLTKEAANYIANTNIKGIGIDMLSVDRYDTSVFE
                     VHHILFEKGKIIIENLTNLETVPEKFLFIAAPFKYNDADGAPVRAIAIVE"
     gene            complement(30974..32053)
                     /locus_tag="PC465_001672"
     CDS             complement(30974..32053)
                     /locus_tag="PC465_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HDF2648989.1"
                     /translation="MKIAIFLGAGASAAENLPIQNELFSEYFKKLNPTNYNTKMNREL
                     YIFFKQMFNIDIVKDNIDNANFPTFEEVLGLLDLAEQRKEAFRNFGLENLNNRSDSIR
                     FLRQYLILLMAEAIHNTPRTDNKYHKLLVENLLENDLLLDTTFISANYDIHIDNTVTG
                     LRDKNDLPIMLDYGVEFTNFKEELNWRKPKEPLIKLYKIHGSLNWLYCPICNSVTLTP
                     HEGGVMKLIENSSETKCLECGELTEPIIVPPTYFKNMSNIFLSNVWNETEKTLRDTDL
                     LIFCGYSFPEADMHIKYMLKRVQTNRKKPPLKIMVFNNHSQKQRITLKKEEGRYKRFL
                     GEDVIFTDNSFQDFSVNPLRFIKNI"
     gene            complement(32186..33532)
                     /gene="pepV"
                     /locus_tag="PC465_001673"
     CDS             complement(32186..33532)
                     /gene="pepV"
                     /locus_tag="PC465_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HDF2648990.1"
                     /translation="MKEQIKEKVNSLQDEMISSIQESVKIPSVISEATENCPFGENVD
                     KALRGILDLCKSLGFKTVYKDGYYGYAEIGQGEKMIGILGHVDVVPEGDLESWNYPPF
                     EAVLEDGKLYGRGTQDDKGPTIAAIYAVKALMDLNVDFNKRIRFIFGADEENLWRCIN
                     KYKENNEEIPNYGFTPDSRFPITNAEKGLLQVHLTCDSKSDIELSVGKALNAVPGKAI
                     YIGKYSDKLKKELDKLNFEYTVEGNKICIIGKSVHSAASDTGINAVARLCIALNNIGI
                     DSNIIKFLAEVIGEDANGNNIIPNCKDDVSGKLTVNIGRVTIDNEKEFAGIDVRIPVT
                     YKKDDFVKELKKMTDKYNLNYEEYDFLDSIYVPEDTLLVKTLRKVYEEETGLDGTPLS
                     SGGATYARALDNCVAFGAIFPGKPETEHQANEYLIVEDIIKATQIYALSIYELLKI"
     gene            complement(33601..34881)
                     /locus_tag="PC465_001674"
     CDS             complement(33601..34881)
                     /locus_tag="PC465_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine gamma-lyase family protein"
                     /protein_id="HDF2648991.1"
                     /translation="MLNETKELLKDYYGIDDDTFKLSQEIMEEIKDKFEEIKEIREYN
                     QYKVLKAMQESKLSDMHFNWTTGYGYNDIGREKIEEIYSKVFNTEDALVRPIIVNGTH
                     ALTLCIQGIVRPGDEILSVTGRPYDTLEGVIGIREEKGSLKEYGVTYDDVDFLEDGNL
                     DLEGIKNKINDRTKLVMIQRSKGYSWRKSLSISDIKEAIEVIKSVKPEAIVMVDNCYG
                     EFLDTKEPTDVGADVMAGSLIKNPGGGLALTGGYIAGRKDLIELISYRMTSPGIGKEC
                     GLTFGTTRNVLQGFFLAPYIVSQAVMGAIFCSRAFEKLGYDVLPKYDDLRSDIIQCIR
                     LNNADEVISFCEGIQEAAPVDSYVKPVPWDMPGYESEVIMAAGAFIQGSSIELSADAP
                     IRPPYNVYFQGGLTFDHSKMGTLKAIEFIKKLKK"
     gene            complement(35008..35268)
                     /gene="hfq"
                     /locus_tag="PC465_001675"
     CDS             complement(35008..35268)
                     /gene="hfq"
                     /locus_tag="PC465_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HDF2648992.1"
                     /translation="MKNTVLNLQDLFLNNARKERIPVTIYLVNGVQVKGLVKGFDSYI
                     ILIEGDNRQQNMIYKHAVSTIQPGKYINLTNQNQNNNNNNNR"
     gene            complement(35382..36317)
                     /gene="miaA"
                     /locus_tag="PC465_001676"
     CDS             complement(35382..36317)
                     /gene="miaA"
                     /locus_tag="PC465_001676"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HDF2648993.1"
                     /translation="MKKIPLIILTGPTAVGKTDLSIKLAKDMNAEIISADSMQIYEYM
                     DIGSAKVTEEEMQGVKHYLIDEVKPDYPFSVSEFQQRAKKYIHEINEKEKCVLVTGGT
                     GLYLNSLIYNMDFAQSDANNELREELQKQLAEKGIDYMHNKLKELDEESANRIHKNNT
                     KRVIRALEVCLSGKKMNDFSSDLKFNEEYQPIIIVLNRDREHLYQRINMRVDIMLKNG
                     LVEEVKKLLSMGFKKDMISMQGIGYKEILKYLDGEYTYEEAIEIIKRDSRRYAKRQIT
                     WFKRYKTAKWFDLDQYENIDELKNEIILYIKDSIK"
     gene            complement(36355..38322)
                     /gene="mutL"
                     /locus_tag="PC465_001677"
     CDS             complement(36355..38322)
                     /gene="mutL"
                     /locus_tag="PC465_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HDF2648994.1"
                     /translation="MKNIINILDDLTINKIAAGEVVERPSSVVKELIENSIDAGANKI
                     SIDIIDGGKSLIKITDNGIGIPSSEVEKSFLRHATSKIKKIDDLYDLYSLGFRGEALA
                     SISAVSKLEMTTKTKDEIIGTKIYVEGGKIISKEPIGSTNGTTIIIKDIFFNTPARQK
                     FLKSTHAETINISDLINKLAIGNPNIQFKYTNNNKQMLNTPGDGKLVNTIRSIYGKEI
                     TENIIDVEFKCNHFKMNGYIGNNNIYRSNKNLQHIYINKRFVKSKIIIDAITESYKSI
                     IPIGKHAVCFLNIEVDPSCIDVNIHPNKLEIKFEKEQEVYIELRDFLKVKLIHSNLIG
                     KYATYSDKKTQPRIAINSREKSTDYKLRNNDLLESTPKKSNITKGKDEVIEVVTLSSE
                     KPINEFQSVSEVLNASVEDDVKNINYLSEDSANDNIQEEFQVDGIKNEGNYYLGDSIK
                     DSEEEYSCSSKRKFSLYGYSVIGVVFNTYIILSKDDSMYLLDQHAAHERILYERYMEK
                     FYRQDINMQILLDPVVIEVSNVDMLQIENNLELFMKFGFELEIFGNNHIMVRCVPTIF
                     GVPETEKFILQIIDNIEEITSNYDLKGERFASMACRSAIKANDKIYDIEIKSLLEQLE
                     KCENPFTCPHGRPIMVEISKTEIEKMFKRIM"
     gene            complement(38333..41176)
                     /gene="mutS"
                     /locus_tag="PC465_001678"
     CDS             complement(38333..41176)
                     /gene="mutS"
                     /locus_tag="PC465_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HDF2648995.1"
                     /translation="MQIDMNKLTPMMKQYLEVKNRYKDCILFFRLGDFYEMFFEDALV
                     ASKALEIALTGKACGLEERAPMCGVPFHSANSYISKLVENGYKVAIGEQMEDPSTAKG
                     IVRREVIRVITPGTVLDGNLLENKKNNYLLSLYKDGTNIGLTYVDISTGETNATCLNE
                     DKVIEEIAKIHPTEIIINDLDFIEKLRDIATVSNIYINESFSDNYLDINILKEYFPDV
                     YLQKLKFDDKGLIKSSLSILLNYIYNTQKQITSNINNINIYNSSEYMVLDMFTRTNLE
                     LTQTIRGNKKKGSLLHVLDKTSTAMGGRLLRKYVEEPLINKSKIENRLDVIEEIKDDF
                     ILREDLNDILKNIYDIERICGKIAFERVTPKELIHLKNSIEKLPNLKDTINLSNAKIL
                     KEYVSEMDKLDDIYNLIDEAILEEPTITIKDGNIIKSDFSDELKELREISKNGAFLVK
                     EIENREREKTGVKSLKIGFNKVFGYYIEITKANFKQAKLDETYIRKQTLSNAERYITP
                     ELKEIEEKILHAEEKIKSLEYEIFVEIRDTIYKNIDRIQKVAKTIANIDVFVSLATVA
                     HINNYVKPAINENNKLDIRNGRHPVVENIVGEENFVPNDTYLNRGENIINIITGPNMS
                     GKSTYMRQTAIIALMAHIGSFVPAESADIPILDRIFTRVGASDDLSQGQSTFMVEMNE
                     VSLILKNATERSLVILDEIGRGTSTYDGISLAWSIVEYIQKNIRCKTLFATHYHELTD
                     LEEEFKEVKNYSIAVKEDGEGIIFLRKIIPQGADKSYGIYVAKLAKLPDEVIERAKYI
                     LKDLEKNHVYNSVAINGDKENNNIINSNLDEELVKVNQSNFKNKYESLKIEHELIVKD
                     YKHIKKDYDKLNSKFKALNDEVALMKQNDDKEKINQEDSVKEVALTQISFDSVNRDIL
                     SEEILNLDILNMTPLDAINSLYNLQRKAKEIKS"
     gene            complement(41337..42071)
                     /locus_tag="PC465_001679"
     CDS             complement(41337..42071)
                     /locus_tag="PC465_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2648996.1"
                     /translation="MLTQMNFYHNKKVKVSIENVSKTYKDIKVLKDISIDVYEGEFVS
                     ILGPSGCGKSTIFNIITKLTDYDSGKVNINGKYSYMYQKDLLLPYKTIIDNVSLPLIL
                     KKEKKSKARSMVKPYFEVFGLSGYEDKYPSELSGGMRQRANFLRTFINSNDIMLLDEP
                     FGALDSLTKTSMQKWLLDVKKKVNSTILLITHDIDEAIMLSNRIYVISKKPSIVKKEF
                     VIDSRKLNEDNLENIIKLKKEIISLL"
     gene            complement(42040..43053)
                     /locus_tag="PC465_001680"
     CDS             complement(42040..43053)
                     /locus_tag="PC465_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2648997.1"
                     /translation="MNFKKLGILGLVSVFTLATITGCSSNNNKDKNNDKDTSSKKVTM
                     VLDWTPNTNHTGLFVALDKGYYKEEGLDVEIVQPPESGAETLVATGKADFGISYQEQV
                     TYAKTSEDPLPIKAVATVIQHNTSGFASPKEKNITTAKDFEGKTYGGWGSPSEEAVFK
                     AVMKKNGADFNKLKIVNTGQDDFFAAMKTVDFAWIFEGWDAVKADLIGYDLNFIPVKD
                     LDERLDYYTPLIISNETVLKDNPELAKKFLKATTKGYEYAIKNPEESAKILVKHAPEV
                     DEKLALKSQEYLASKYKDDAPRWGEMKDSVWNNYTSFLKEYKLIDKDMKASDAYTNEF
                     LPQ"
     gene            complement(43075..43845)
                     /locus_tag="PC465_001681"
     CDS             complement(43075..43845)
                     /locus_tag="PC465_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2648998.1"
                     /translation="MKNLEIIDKVKDSIYPIATFLFILILWQSMVGVLEVPQYILPTP
                     VDIINVFFKDYQNLSMHAVVTIGEAILGFIVAIIISLVIGILMDFVSIIKKCLYPIML
                     VTQMIPTIIIAPLFMIWFGFGTMPKVLMVMLTCFFPILISFVDGIENIDKDYLNLFKT
                     MDSNKVNTFIHLKFPMAMDKFFSGLKISATYAVMAATVAEWLGGTKGLGVYMLRSKSA
                     YALDKVFASTILVVIFSLMFVGIVQAVKKVVIRHRLID"
     gene            complement(43820..44110)
                     /locus_tag="PC465_001682"
     CDS             complement(43820..44110)
                     /locus_tag="PC465_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HDF2648999.1"
                     /translation="MVIADIAVMPLRPYKGEEEMYKVVDACIAEIEKSGLKCEIGAMS
                     TTVEGDFDEVFELLKKVHKIPFNLGCERVITVARVDEKAGGLTIDEKLRNHR"
     regulatory      complement(44241..44340)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     regulatory      44960..45049
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            45102..45278
                     /locus_tag="PC465_001683"
     CDS             45102..45278
                     /locus_tag="PC465_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649000.1"
                     /translation="MFMDKMDRCTHILTAYICSSRDYCNFIDTQLNDFILEYGENVVE
                     SCLHQVMVLVSRYN"
     gene            complement(45393..45749)
                     /locus_tag="PC465_001684"
                     /pseudo
     CDS             complement(45393..45749)
                     /locus_tag="PC465_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428797.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            46005..46919
                     /locus_tag="PC465_001685"
     CDS             46005..46919
                     /locus_tag="PC465_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010966716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
                     /protein_id="HDF2649001.1"
                     /translation="MNKKFRLYQVDSFTKEKFTGNPAGVITNADGLSESQMQKIAREL
                     NNSETAFIFNNLAKNHQENYDVHIRFFTPTNEVPICGHATIAAHYVRAVENQFNNKTV
                     FQKTGAGILPVDIIKKDNDYEIIMTQGKIEVPPPLQQTYQKRLLNAFGILKKDIRTDC
                     PIAISSTGHSKVMIGIKELSTLNSLSPNLYELSKISQEIKCNGHYIFTLHNKETLQVH
                     GRMFAPAIGISEDPVTGNANGPLGAYLVHYKVIPTPNTEFIFEAVQGEAIKRKGKMLV
                     KVIILDNKPVEVKIIGKAVIAFSTNIEI"
     gene            47150..47761
                     /locus_tag="PC465_001686"
     CDS             47150..47761
                     /locus_tag="PC465_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HDF2649002.1"
                     /translation="MINDIKNKFKNYKPYINGYKNMKRASVLIPIVEINNTHYILFEV
                     RSKNLKHQPSEISFPGGKIESGETPYEAVIRETCEELGTFSDNIEVISSLDLLITPVK
                     FIIHPYLGYIKNINNLNINKDEVDHTFLVPIKYLLENPPNTYSNTVKVFPDENLPYGS
                     IPNQKDYKFESGSYPILFYKYKDYVIWGMTAKILENFLNFLSE"
     gene            48059..48397
                     /locus_tag="PC465_001687"
     CDS             48059..48397
                     /locus_tag="PC465_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HDF2649003.1"
                     /translation="MFAVGFVVIIALAFFILSVLLFNGKASMLLAGYNSMSNKEKARY
                     DKKKLCRSSSIVTFIVSIMLFIMAFLGYRIESGQMDEKKMVPFSIIFIIVILSSVFFN
                     ILYSNKKCKK"
     gene            complement(48804..50240)
                     /gene="miaB"
                     /locus_tag="PC465_001688"
     CDS             complement(48804..50240)
                     /gene="miaB"
                     /locus_tag="PC465_001688"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HDF2649004.1"
                     /translation="MSKRKQVTIPIEKIQEQDKYIEQIHRQNEEYFNRTGKRKLVFTQ
                     TFGCQMNEHDSEKLCSMLEEMGYQMSMMVEESDLIIYNTCAVRENAELKVYGNLGQLK
                     HLKGKNPDMKIAVCGCMMQQPHVVEELRKKYKHVDLIFGTHNLYKFPQLLTESINSDK
                     MLVDVWDVDGEVIEGLRSNRKFELKAFVNIMYGCNNFCTYCIVPYTRGRERSRTPEDI
                     INEIKELVANGTKEITLLGQNVDSYGKTLENPVSFSELLRKVNDIEGIERVRFMTSHP
                     KDISDEVIYAIRDCDKVCEFLHLPIQCGSSSLLKKMNRHYTKEYYLEIIEKAKKEVPG
                     IAFSTDLMIGFPGETEEDLLDTLDVVEKVRYDSAFTFIYSKRQGTPAAKMENQIPEDI
                     KHDRFNRVLEAVNRISAEINDGYKDRIVEVLVEGRSKNNENKFAGRTRQNKLVNFEGG
                     NDDLIGKLVMVKITEPRTFSLNGILVNN"
     gene            complement(50488..51924)
                     /locus_tag="PC465_001689"
     CDS             complement(50488..51924)
                     /locus_tag="PC465_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp28"
                     /protein_id="HDF2649005.1"
                     /translation="MKFYKRILTLTLSISFVFANIQLVDAISSVEKIQGKNKYEIAGK
                     IADKNAYKTAILINTSNSIADGLSASGLAGALNAPILLTEKNTIPTETSARLKNVSKV
                     YIIGGTYSISTSVENSLKSKKMKVVRIKGNDRIKTSYNVAKEINSIKKVNTVMLTNAY
                     KGEADAISIASVAARDKAPIILTNGQSIPFSTSGLKSYVIGGTASMSTTLVNNTKSTR
                     LGGSTRFETNKAIINKFYKDAREFYIAGAYELTNALVGSSLSKHGPMVLVNDGSNKSI
                     LKNAKKITSIGYIDSNIVQQCLNITNGIGDINTGVVKNVKPTTKTIKDGMYKVGKDIS
                     AGEYLITSNSGSYASYYEVTSDSTGNADSILSNDIFSGTRYITLKNGQYIKIEDSTMT
                     LAKYAKAQKAKNGKFGNGMYKIGLEIPAGEYIIMSNSSDAYYEVRNDSLGNAEGIVTN
                     DTFSGRRYITVEEGQYLILNDCYLIENE"
BASE COUNT        17793 a         8057 c         5947 g        20210 t
ORIGIN      
        1 ttatatactt taaaatatct aagaaattat tcaataaaaa aatactattt tttaaaaatt
       61 atcattattg ataaagctct actatttata ttttttagtg tattcatgta taataagtaa
      121 aagcacaacg gtatatactg ttgtgctttt ttgtaattaa taaacaatat tttggtctat
      181 aacaatgaaa aatggctact ttccataatt gatttcatct gacataagca aaaagggtgt
      241 ccagctgggt caatcataac tctccagtca tcagtaaatt gctcctctgc gattgtagct
      301 ccacaatgaa ttgcatattg aactgcttct tctaaatcat taacagcgaa atccatatga
      361 gccatttgtt gttgagattc aggtttttct ggttctatta tgccccaagc ctttgttttt
      421 tgcaatataa agaaaaaatt atatatttta atattttata attgttgaaa ttgtgtaata
      481 aattcaactg gatacatagt gcgttttgaa atttcttcta aagctaaacc ttgttttaaa
      541 agtctcttta tgacgctttc catactttct gaaatttcta taatattttt atcaaaatca
      601 taaaacctaa aagttctttg accccatggg tattctttta tataatgcaa aaattcaata
      661 tttcctattc tatttatctt actttcccat tgtttgatgt cattaacctc aaaatacaac
      721 tgaaagttat ttgattgttg atatattggt aaatcatatc caattatagc tttataatta
      781 ctttgtaatc caaatccatt ttcaaatgat acatgttctc ctaaatctaa tgtgattttt
      841 tgctccataa catcttcata aaactttttt gatttattta tgtcttttac aattagcaat
      901 actcctccaa atttcatctt atcactatcc tttctttgtt ataagtatta taacttaaaa
      961 ttttgcaatt tcactgtaaa aatcagacat attagctcgg tatttttgag gagttattcc
     1021 acagacaatt ttaaaatctt taataaaatg tggtatatca tagaatccta attcattaca
     1081 tatagacatc aatgaagttt tattattgtt tagaagtttt atagatttat taatacgtac
     1141 caaacgagaa aatgacttca tactcaaccc taggtactga ttaaagagtc tgtttaaatg
     1201 cctagaacta taaaatactt ttttagaaat ttcttgtgaa gatatatttc cagagttttg
     1261 aataatcaac tgaattgcca aaataaactc atatgagtat tcaattttaa tattagaaat
     1321 caataattct tccaacttta aaatcaattt atctatagat aaagattcat taaatatttt
     1381 tttaatttct aaatctaatg aagtattaat tatagaaaat ggaacaactt tatcaataag
     1441 ttcactttgc tgtataccta taagcgggaa aaaaccagca ggttgaaatt ctataattag
     1501 tataacatca catctattag caatatttcc tactgttttt ggtttagtag ttggaccaaa
     1561 taatagacta tgtaaccctg tggcatcata aaaaaacacc aaagttacac ttccatgagg
     1621 aataatcgtg taattatcag aaattattgt ttgatttgga aacgatatag taaaattcga
     1681 tatccaattt cttaattgta tacaaggcaa gagataaaca aaattgtctt cacaaactat
     1741 aagtgaccta tttttattta taaaatgaat actttctttt tttaacatat attatatcct
     1801 gtcctatcgt gaatatttat taaagtaaga agaatccata ttatctctat atatcattaa
     1861 ctgcttttaa taatagagat agtatgaata ctcattagat atttaataaa caaataaaat
     1921 taaaataatc aataaaaaat atagtacttt tatctgttat tttaatatta tagcacattt
     1981 atagtattta acttatatcc actttacata tgtctaattt atatagttaa aaatgcttat
     2041 ctcaaataca ataattagtc cttatacaat taaaccatct gaaactgtaa tagtacgact
     2101 actacttttg gctgcttctg gtgagtgagt taccataatt atagtttgtc cattgtctct
     2161 gtttatttta ttcagtaaat ctattatttc tatccctgtt ttactatcta aatttccagt
     2221 aggctcatca gcaaataaaa tctctggttt tccaattaaa gctcgagcta tagcaacacg
     2281 ttgttgctga ccaccagata actctcgtgg tgtatgttta cgtctatcag ttaaaccaac
     2341 tatatctaag atttcatcta attgattttt ataatctttt aaatttttac catctaataa
     2401 caaaggaagc attatatttt cctccacatt taaatttggt attaagttat aaaattgaaa
     2461 cacgaatcct atatttctac gacgtattat gctcattttc tcatcattaa aatgtgatat
     2521 atcagctcca ttcatataca cttttccgct cgttggagta tctaaaccac ctaaaatata
     2581 taaaagagta cttttaccag aaccagattg acccatgata gaaacaaatt cacctttcat
     2641 tacttgtaaa gatacctctt ttaacactcg agttgttgta tttccaattt tatattcttt
     2701 gataatattt tttgcttcta cagctaaact attatgtgta attttcatat taacctccat
     2761 aattattcaa acttaatttc ttctatcagt ttcattttct tcccttttat aataggcact
     2821 attgaaccta ttaaagttac tataattccc aataacccaa caataataaa tgttttaaaa
     2881 tctaaatctg gtttcattga aatttttggt cctgcaacta taaagatagt ttgaatctca
     2941 agtatagata tcacaatacc aataacagct ccaagtaaac ctgaagtaaa cccttcaatc
     3001 aatgttactt ttatattttg tttatcactt agtcctatag atttatacat agctatagaa
     3061 cgtctttttt gaatataatt aatcagtaga ttattaataa tacctactgt agcaagaaga
     3121 aaaatgaaat aggtcatctt attcatagga gacaaaaaac tacttatagt atttaaagaa
     3181 tcattattaa attcttcaac tgtacgactc caattatatg tatctccaaa taaatatctt
     3241 atctgaatca taacagcatc tggattgact gctgtatata ctaaaaaacc ataattagtt
     3301 ttatcaaaat cattaactgc ataatgtgat ggtataacag cttctacatc atttgcacgg
     3361 gatttaaaac tacctactat tttataagaa aaatcatact tatcattaga tagagttatt
     3421 gtatctccta tagataagcc tacttttttt agagtatctt cattcaaaat aacagaacgt
     3481 ttatcattaa aagcttctat tacttgtttt tttatctcaa aatttgtata attgattcca
     3541 aacatagagt tatatagttt tatattatct gtaccctcta gtcttgataa tgttacacca
     3601 ttaccagaaa tctcattatt cataacataa agaggtaata tttttttaat tccatccata
     3661 tgtctaacat cttcaataaa ctcttcattc atctttccat ctgcaaaacc ttgtaattct
     3721 gcgtcacgaa acacatctgt tatataagtt ttgacaaagt taccaacaac acttattgca
     3781 ataactgcag aaatacttat aaatagtaaa gtgatattct gtattatatt tttgttattt
     3841 ttcatatttc tagcagctaa tttaccctca ttccctaaaa tatttttata aacaaactca
     3901 aaaactatag acatgatatc agtaataaga ggaatcaaca caatagtagc tacaattaat
     3961 cccagtaatg aaaatccacc agctagatac aatgtatttt caggggatat tcttggaagt
     4021 aaaatagata aaataaacat tatacttcct ataaaaagta tagaacgatt tgaaacattc
     4081 ttttcttcta ctgttcctag tacaatattt tttatcggca aatggctagc ttttttaaca
     4141 ggtatatatg cactaaatga agaaacgatt attgctacta taacagatat aatcactcca
     4201 atgggtgata ttactactgg aattgatatt ccttgctcga gagaatttcc taacccatga
     4261 agcattaaat ttaaaacaac tacaccaata ggaatagcaa ttaatcctcc tatacttccg
     4321 tataatatac tttcaagcat caatatacga gttacagttt tttcattggc accaatactt
     4381 ctaaatgttc caataaaagg aagacgttct aatgtaataa ccttataact gctgtatatt
     4441 ataaatatac taagggttaa tgcaaaaaaa cttattaaaa agaaaggcat tgtcttttgt
     4501 ctagcatctg aaattatctt agtttcattt atagtatttg ataccatata tttttcagta
     4561 gaaagttctt tggataattt atttactaga ttttctgtaa tttcttcttc tgactctata
     4621 agaattcttg tatatccact gcctttattt ataatttttg atagagtctc tttgggtagc
     4681 agtgcattta cacctcttgt gttcctcaaa aatactgtat cataagatgc aatatcacta
     4741 acttgaaaag tataagactt tccataaatc tgcaaagtaa tagaatcacc tttttttatt
     4801 ttatattttg atgtaaagcg atttggaaga ataattttat caccagaaaa atcagtaata
     4861 ctatcgccat tttctaatcg tggcttgttg attttattta gttgacttaa gtctgctgat
     4921 ataagactaa attcttcata gtatccccct ttattataaa tagcagagct ttccaataca
     4981 ccaacctttg attttatagc atttaaatca ggtatgtctt ctaaattggt taatatatct
     5041 ggatttttac tttggacaga tatagtcgct gtaccataca taccttttgc catttttctt
     5101 tgtgcacttt cataagataa tccaattgag aatgaaacaa aaagtaaaac tgttgataaa
     5161 actatggaca ataacataac tgctgttcta atttttcgtt ctttaatatt tgtgaaaata
     5221 tactttaata taattttcaa atttacacct tctttcctta tctaagatat ttcaatctaa
     5281 tatttttata ctttaatcta aattaaatct ctaatagact cctccatact tttatcattc
     5341 tatttataat atttttaatc aaatcacccc ttaaataaaa aagattgata aactactata
     5401 taaatataat aatctatcaa ccttaatata ttttttattt aaccttaatt aaccttaatt
     5461 aaataggaaa ggtgatataa aatgagctac ctaatccagg tatactttca acagatatat
     5521 tccctccatg aacttcaata atttgcttcg ttattgctag tcctaaacca gttccttcta
     5581 ttttttgttt tgtattgctt cctctataat aacgattaaa caaatttgat gcttcttctc
     5641 ttgacatccc ttttccatta tcagatataa tgatttcaat tctttcattt aatgttatat
     5701 gtacacaaac tttagtattt ttatctccat atgtaaaagc attgacaata agattactaa
     5761 aagctcgttt taatagtgta caatcaaaat caaagttaat attatctata ttactcttaa
     5821 attcaactat atttgattca tattctggat aatttaaaat atcaatggat aattctttca
     5881 aaaatcttac taaatcataa ttatttttat ttaaagggat tattccattt tttaattgat
     5941 aggttaattt taaatcgttt ataagtgtat ttgtatattc tatgttcttt aacatgattg
     6001 aagcatattt atgtactttt tcaggtgaat aattagtact actatctgta agaagctctg
     6061 catacccttt tattggtgaa agtggagttt ttaaatcatg agttatattt gaaatccact
     6121 cttctctcat aatatcagtt ttattttgta tctcatcact tttatgaatt tcttcattta
     6181 aaatatttaa actattatat atatcagcaa aaacaccttt aatattaact ggaagatagc
     6241 ttcgttttga aatatcgcta acagcagatg taatatttga tatgcacttt gttacccagt
     6301 aaccataagc aattccagaa accaaaatta ttaaaaatat aatccctatg attgaaaata
     6361 taattgactt accacctata aatttacctc catcaaaaaa catattcact ttagatatat
     6421 ttaatggaaa atatataata taaatatagt catttttatt atttttaatt gtattaaagt
     6481 atacagttcc attacttgaa ttattttggt tagctaatgc taataattca gaattagaat
     6541 aataatcttt atgctctttt ggttctaaaa acccataaac tctatttcca ctagaatcta
     6601 aaatttgcaa ccacaattga ttttctcgaa gtttttttaa tccagactgt tttacttgtg
     6661 gcttattatc tataaatacg atttgttcat taaagttttc tgtaaatttt ttcggccagt
     6721 cactacgaat aaattcccca tttggtttct gaatagtaat aagtgataag aaaataccta
     6781 ttactgtcag gattaagcaa ataaaaatca tgaaaaaaat aatgtatgaa tgaaatactg
     6841 ttttataact aggtttatgc atttaatcaa ctcttttctt aaacttttat tttgattgtt
     6901 gcttatataa aatagacaat aattattgat atgtaaaaat ttatttaaaa atacaactat
     6961 ctacataaat tatatttata taattatatg ttatcaagct gtctgttgta tttaataaat
     7021 cattttgata acatataaaa gtaagataaa tttttccatc aaatacctta taattataca
     7081 caaaatctct atatacgtta aacagtatag agaaaatttt catagaacca tctttatagg
     7141 ggatacttta taaaagaata aaaaaattat aatatataaa aaacttcata ggagtgtaac
     7201 aacatcagta aagatatgaa aacactatat aaaaattcaa aaatattaag aataatgaaa
     7261 tacttgaaat tgcttatatc aagaaatttt atataatata aactggtcaa atatgttata
     7321 atattaaatt gtgacaagtt catggaggtg tttatatgaa aaaacaaaag tcgccaattt
     7381 tacttgaaat gcttggacta ttttttggtt gtatatcaat gagtattggt ataaatatgt
     7441 ttttaaaacc acatacaatt gctcctggag gacttagtgg tctatcatta gtactaaaca
     7501 aggttacagg acttccagta tcagctatca tgttaattat aggtgtccca ttagtaatac
     7561 ttgcttttag aattatgggt acaaaaaatt cattaaaaac tttatttgga acagttgtat
     7621 tttcagctat agttcaatta acagacccat tatcaaaact aagatttact aatgacttat
     7681 tattgtcttc tattgcagga ggaatcctag ttggtatagg tttaggaata atgtttaaat
     7741 cagatgcttc tactggagga acagacttaa ttgcactcat acttagtaag aaattcccag
     7801 gaataaaagc tacaaaattc atgtcatgcc tagatggaat ggttgttata tcttctggta
     7861 tagtaaatcg tagtttagaa actgctcttt actctggtat agcactttgt gtattaataa
     7921 aaatagcaga tatgataatg gaaggatttg accattcaaa agcatttttt attatctctg
     7981 atgagcctga aagtttaaga caagctataa ctgaagaact tgatagaggt cttactattc
     8041 ttgatggtaa aggtggatac actagagaaa ataaagaagt tctattagtc gtagtttcta
     8101 aaaaacaaga actttatcta aagagattag ttaaaagaac tgaccctact gcatttgtta
     8161 ttgttacaga tgtacatgag gttcttggag aaggatttaa aaatttagag aactaataaa
     8221 aattaatatt ttaagtatat atactatttt aattaaaata cgatttattc aaaaagagtg
     8281 tctcataaac tttttagttc atgagacact cttttttgta taaaatcaaa tgcattttca
     8341 gtattttaac aataaaaaca ggattatcta tattttgagg caaccacttt attgaaattt
     8401 tatttagaaa acaatcatta ctaaataacc agcatagata ttaaatgatt atatctattg
     8461 ttttttcaat tcatattgat aacaaggaac attttttaca gtatttccag tatgaatttt
     8521 tttgatatac tttcctgtac atttaaatcc taataaatct aatgattttg tagaattttg
     8581 gttttcttca taggttattg caattatttt atttaagttt agttctctaa atccatactg
     8641 tattactctt tttgttatct cagtagcaaa atcatgtccc caatagcttg gatttataca
     8701 tatacctatt tctgcttcta atgctttagg atttatatta ttaaacccca tatttccaat
     8761 aactttattg tctcttttat atactatagc aaagtggcca attttccctt ttttatatgg
     8821 atttagaaaa aatgatttta taaactttct tgtatcttct aaagatttat gctcactaaa
     8881 tggtaaatgt tttactacta ttttattttt ataacagtca aaaaaatctt caacatcatc
     8941 taatgatgca ggtcttagta tacaacttct agtttctaag gttttcattt gaggatattc
     9001 agaatcagac atttctaatc cccctttata cattaatcta aatatactgt tcatatttaa
     9061 aatacgatat taattatata aatgttctca aattaacctt atttttattt ttaataaaaa
     9121 ctaattacta tatgaatctt tcaaatttac aaatttatct ctatttttat attaaattac
     9181 ttgtgaaata tgtattctaa attatatatt attagatatc atgcttaaaa attctttggt
     9241 tgctaaggat aaagatatat cttttaaatg gcaataacct atatttctct taggtattgg
     9301 ctcttttata tctaatttaa acaatttctc attttccaaa taatctatgc taaattcttc
     9361 tataacacaa gacactccaa gatttatata cgcaaattct aaaagtaatt catgagaacc
     9421 caattctata tccgggttta gttttatacc ttttgataaa aaatattcat ttacataaag
     9481 tcttgaattt gctttatttt ctagcattat taaaggcaat gtgtttaatt cttccaatga
     9541 tattttccta cctttgtatt ctatgtaatc atttgcacat acaaatatat catgtatttc
     9601 aatacattca acaatattta gtgtatcatc ttctattggc atgtttataa ttgctatatc
     9661 tatattccca tctttgagta aagatataag ttctctactc gttctattta ttgtagatac
     9721 atgtatatgt ggatacttct tatgaaaaat ttctaaatat tttaacaaga aaaaacgtgc
     9781 agctgtattt cctactccta ttttcagaga accgtattct aattttttaa atttatttat
     9841 tctatcttct cctgatgata ttaactttaa tgcagtagtg acatgttcac ttagaatttt
     9901 cccctctgga gttaatttta ctcccttatt gtttctataa aataataaag tatctaattg
     9961 ttcttctaat tgctttattg actggcttac agctggctgt gacataaaca attccttagc
    10021 agcaagagaa aaactcttat tatttacaac tgcattaaaa accttataaa gttcaagttt
    10081 tatattcata tataattact ccttatgtca aatattagta ttatttattt tacttataat
    10141 tatatttgaa ttataatata catggtacta atatgacaat attaattctt taggaggatt
    10201 ttagataatg gatagattag ttggaactgt ttcaagaggg gttagagcac ctattataag
    10261 acaaggagat gacttagtta aaatagttgt tgattctgtt ttaaatgcgt caaaaagtga
    10321 aaactttgaa gttagggaca aagatgtaat tgccgttaca gaagctgttg tagctagagc
    10381 acagggaaat tatgctcacg ttgacaatat tgcaaaagat gtaaaagata aatttggaga
    10441 tgatactgtt ggggttatat tcccaatttt aagtagaaat cgttttgcta tatgtttaaa
    10501 aggaattgca aaaggatgta gaaaagtcgt attaatgtta agctaccctt ctgatgaagt
    10561 tggaaatcac ttaataagta ttgatgaact tgatgataag ggaataaatc cttggtcaga
    10621 tgttttaaca gaagaaaaat acagagaact atttggatat aacaagcata catttactgg
    10681 tgtagattat gttgattatt ataagaattt aatcaaggat tgtggtgcag aggtagaaat
    10741 agtatttgca aacaatccaa aaactattct taactataca acaagtattt taacttgtga
    10801 tatacataca agacaaagaa caaagagaat tttaagacaa aatggagcta aaaaagtata
    10861 ttcacttgat gatataatga cagcaagtgt agatggtagt ggttacaatg accagtatgg
    10921 acttttaggt tcaaacaaag ctacagaaga aacagtaaaa ttattcccta taaattgtga
    10981 tgaagttgta aacaaaatcc aaggtaatat aaaagaaata acagggaaag atgtagaagt
    11041 aatggtttat ggagatggag cttttaaaga ccctgtaggt aaaatatggg aattagctga
    11101 cccagtagta tctcctgctt atacaaaagg gctagaggga actccaaacg aagtaaaatt
    11161 aaaatactta gcagataatg attttgctga cttatctggt gatgagttaa aagaagcaat
    11221 ttcaaaatac atagttgaaa aagataataa atctgatgat ttaacaggaa acatggtttc
    11281 tcaaggtact actccaagaa gattaacaga ccttataggt tctttagcag atttaacatc
    11341 tggaagtgga gataagggta ctcctattat ttacatacaa ggatatttcg ataactatac
    11401 aaaatagtat gttttaataa gatttaaatt ttttggatta tatatattaa catgaaaatt
    11461 tattaaaacc tcttaataga tatgactttt caagagttat atctattaag aggtttattt
    11521 aatgttcaca gataagatat atttaaataa tttaaacaag attgtcagaa agttatataa
    11581 tcttaaaaat ttatataact ctaattctta tttatttctg aaataatatc actcttcaaa
    11641 atttgtctta ctggaataat tacagcaact atactaatag tgatatttaa aataatcata
    11701 cctatgtata gaggtgtatt tattttaaga attggattta tatataagta tacacgtttt
    11761 accataaaat aaatcataaa ttgtccaata acacttccaa ttaccattat aatacttgca
    11821 tagaatccat ataaaaaacc ttctcttatc atcataagta aaaacttatt atccgtaata
    11881 cccatagctc ttaaaattcc aaactcatgt cttcttgaaa aaattaagta acttactgta
    11941 ttgattatat ggaacaaact tattgcaaga agtacaaata caataccata tataaataag
    12001 agtttttgat ttaagtaggt attatttttt tcaatagcaa tggtataatc tgttacaata
    12061 catcttttta catcacttac aacacttttt atgttctcag acaattcctc actgttacta
    12121 tcttctgtct tttttatact tactgaatta taattttcga tatcaaagtt atttttcatt
    12181 tgcccattcg tcataactat atccatacca taatcaccaa tgaaatatat gttatttgcc
    12241 atcacacgtt ttacagtagc agcaactaca aattcttttg ttgtataatc attcttattt
    12301 tcttctttaa atttaacaat ttcatctgtt ggtttcattg tctttggcac tttaactttt
    12361 attgtatctc ctggatttat atcaactgca tcatacatcc cagttccatc cataggtagt
    12421 ctaactataa ccttattatt tttaaccata tcatgggtat taatctcccc atctataata
    12481 taagaattta atccttctaa cataccattg ttataaccat aaatatttgt ttttaaaaga
    12541 tagccacctt cattttgctt tgtacaaata ccatcaaaaa aagtctttat cctgtaatct
    12601 ttttcaagag gtttaaagaa atttttccaa aatagttgtt cttctttaat ttgcatagct
    12661 ccaaataaat atcttactgg atagactttt gatattccct caacattgtt taatcttgaa
    12721 attttatctt ttggtatacc tacatcaaaa tctgttgttt gcatagttat ttggtagtca
    12781 gaatttaaac catcatcagc tttcattgta agttcattgt tatttttagt aagctgtata
    12841 gagtaactag aacatagaaa tataattcca ccaagtgata atgaaaacaa aattccaata
    12901 aacattccct ttttttgagt catgtattta tgagataata cttttgtcat gttagagtgt
    12961 tttacacttt ctaatattct ctttttctta ttagtaatct taaagttttt catagattct
    13021 atactagagt atttattcaa ctgatgtaca acacgtacag caattaaaat taacaacaat
    13081 aagataaata aaaagcctaa ataaatagat ttttcactta taaaaaatgc tcctggaaca
    13141 atatcactac tcaaaaatat atgtggaaat tgttcatata ttgtagacgc tactccaata
    13201 cctaagaagc aacctatagg aaatccaaca ataaaaagta aaaataactc taaaaatagt
    13261 agaaataaaa gttgtttatt attagcgcct aatacttcta aaaccccata ttgtgatatt
    13321 ctctgaagta ttgaaacatg gaaaatacta tatactgctg ctgcaccaaa cactccaaca
    13381 agcaatataa ttgcatttgt atttagttct aaatttttta agaactcaaa tatattatat
    13441 ttttctatat tttttggtgg ttttactcca aattcaactg aaagaggcca gtttatataa
    13501 gttttttctt ttgatatgtt gaattttttc ataaatttat aattttgctt tttaatattt
    13561 ttattttcat catattttac ataaactata taagaatcct tttctttagg ctgaaaataa
    13621 tcgtttacaa atccctccag agcagtttct gggtttgaaa gacttgataa aataccacat
    13681 aacttataga ttttaccatc taaattgatt tctgttccaa tttctttgtt tacatttaaa
    13741 ttgtttagag aatatgtgtc aagtactatc tctccatctt tactaggaag agttcctttt
    13801 aataattttc tacctgtcat atctaaatat gaagaatcag catttaaaaa ttctataata
    13861 aaaggttcat ctatctgatt tttaggtttt gtaacgccaa gtctatctac agtgtattcc
    13921 tttgattttt tattttcttt aattttatta agttgttcct tatctacttt atagaaataa
    13981 tgataatctc cactatcttc ccttatcttt tcaattctac ttttgtctgc actatgaact
    14041 aaagaaccaa ttcccgtcaa taatgctact gatagtacta tgcttaaaac tatagatata
    14101 gattgttttt tataatgctt tatatattga attgaaaatt ttactagaga catcatagta
    14161 cttcaccacc agtattcacc acaattccat cttcaatatg gataattgag tcgcatactt
    14221 gtgctatatt ttcattgtgt gttaccataa gtatcgtttg atggaatttt gcactacttt
    14281 cttttaataa acataccact tccattgtag ttttactatc gagatttcct gttggttcat
    14341 ctgctaatat aagcgcaggt ttatttgcca aagctctagc aattgctacc ctctgttgtt
    14401 gaccaccaga tagttcgctt ggaaatttta aacgcttatc ccaaattccc aatgtcttca
    14461 tcagcatttc aatatattca tggtctatat ggtttccttt atctaatgta acaggaagag
    14521 ctatattatc ataagtgttt aatacgggca ttaaactgta gttttgaaat ataaatccta
    14581 tatttcttct tctaaacact gtcaaatctt tttttcctat tttagatatg ttctttcctt
    14641 taattattac atcacctgaa gttggattat ctaatccacc tataatattt aacaatgtgc
    14701 tttttccaga accagaagtt ccaactatag cagtaaatgt atctcgttca atttctatac
    14761 ttactccatt taaggctttt actttagtct caccttttcc atagtgtttt actaaattat
    14821 tcgtcactaa tatactcatt taatttctcc tttcaataca gatatatgtt ctataaaata
    14881 ttgtaagtga cgataattac actcatccta caaaattagt ttaaactctt acaattctgt
    14941 aagaagatac taaaacaaca tccacttcct agtttagatt ctactataat gtttccattt
    15001 tctttttcta aaattaatct tgtaagatat agaccaatcc ctgtgccatt ttggttttcc
    15061 acatttttac ttctgtaaaa tcttttaaaa atatcattta gttctctact atcaatacct
    15121 attccctcat ctttaatagt aatcttcgta tatagttcca tttttattac agaaatagta
    15181 atcgtgctat ctgatggtga gtattttatt gcattttcta aaacatttac aattgcttct
    15241 atggtccact ttttattatg aactaatttt atgtctgaaa atggttcgag atttatcctt
    15301 atatttttag cttctgcttt attaaagata gtactgatac tttgaataag agtatcttta
    15361 attagtagtt cttctacttc aaattctata actccatcct ctaatttagt cattttaaat
    15421 aaggattgta acagccagtc aatcttaaaa gtttcatttt tcatcttttg taaaaactcc
    15481 ttcttctgta atgtggaaat atttatattc tccagaagtt cacaataaat ggttatattt
    15541 gaaagtggag tttttaattg atgtgacata tttgatatta aacctttaat cgcttctttt
    15601 tctgactttg actgttctac ctctatttct atcatatcct taattttttt tacttggtga
    15661 gaaatttttg acgctcttgt atcctttgta tctggataag taacttcttt accttccaat
    15721 atttgattta acatcaaatt taattcatca tatcttcttt gatttatttt agtagatact
    15781 ataaatataa caactgtaca tattataaag gctaatataa acatattatt ctacctcatt
    15841 ccataaataa cccattccat aagctgtttt tatatatttt ggattagatg ggtcatcctc
    15901 tacttttact ctaagtcttc ttatatttac agatacaata ttatcatcaa cataattttc
    15961 ttcgctgtcc caaatatggt gtaaaatttg ttcctttaat aatatttgac ctttattttc
    16021 aattagataa cttagaagct tatattctac agagctaagt tccaaacatt ctttattttt
    16081 atatactttt agtaactttt ggtccaattt tattccattg gaatatatta ctttattatt
    16141 cgattttttt cttattgcta ctttgactct tgcctttaat acagataaag aaaatggttt
    16201 tgtaatataa tcatcaagcc ctatttctaa tccttttact tcatcaattt ctgagtctct
    16261 tgcagtaagc attataattg gtatatctga cttttccctt attatttgac atacatcaaa
    16321 tccatctcca tctggaagat tgcagtctaa gattataaaa tctatatttt tactattaaa
    16381 tatatttaat ccttcttgtt ttgtataagc cttaaataca ttaaatccat cattctcaaa
    16441 tgcataaaaa agaccttcat ttaagtttat atcatcttca ataattaata agttcaattt
    16501 tactctcctt tagatttttt agataaataa ttattttctt gcattatcat actaaaaata
    16561 ttttaatttt atttatttca ctaaaaagat tgtatttaaa tttgttttca aaataaaaac
    16621 atcataatca agcatatagt tatatatttc ccaatttaat tacgcttaaa ttgaaaatat
    16681 aactttattc ttatataatt aaattataca acaataaagt tatatttttt aaatatattt
    16741 ttactagggg gaatagaatt gaaaagggtt gatgagagaa atactatgtt tgcaagagca
    16801 aattacaaaa aagatagtac tgcttataat gactattata agaaaaatcc tgacaaaaaa
    16861 gaaattgatg atagtataag aaatagacca aatttatgta gtgaaggaac aatgacttac
    16921 aatgagttaa actctccaat ggcaagtagt gcattcgatt ttttatctga tatcaaatct
    16981 ttatgcgaag gaaaagtttc tgatactaaa gtagatgtag atgcaaagtc aatgacaaaa
    17041 aaaattaagg gtcttgcaaa gcagtatgga gcttctgtag ttggtataac taaattaaaa
    17101 gactatcata tttatacaaa taggggtaga catgaagaaa attacggtga agaaattaat
    17161 ctaactcata agtatgcaat tgtatttgga tgtgagatgg ataaagaaat gataaataga
    17221 gctccaatga tatgtgaagt tatagaaaca tcaaagtgct atgtggatgc atctatcgtc
    17281 ggcatgattt taagttacta tataagaaat ttaggatatg atgctagaaa tcatatggat
    17341 gctaattatt tagtaatgcc tgtttttata gctcgtgatg ctggtttagg agatatagga
    17401 agaaatgcta tacttacgaa taaagattat ggctctagac ttagattagg tgttgttact
    17461 acagatattc ctcttttaga agatgaatat gttgattttg gactagaaga tttttgtaag
    17521 gtctgtaaaa aatgctcttt taactgccct tctcattcgc tttctaatga tattaaaatt
    17581 ggtgatgatg gaaaatataa ttgggtaatt gaacatgaga catgctatat taaatggaga
    17641 tatttaggta cagattgtgg tatgtgtata tctgcttgcc catttagcca aaatctcgaa
    17701 actataaaga atactacttc atttaagggt aataatgagc ttattcaaaa agctttagat
    17761 gagtatactt caaaatttgg taaaagaata tttatacctg gaaatccatc ttggttgaaa
    17821 taattttatt taataaagaa tctgtactag aatttatcat aggacaggtt ctttattaaa
    17881 tatataaatt tttaaatact ttttctcgtt tataacaatt cagcaatgtt tttagtctat
    17941 aattgacatt ataaaatatt aaactaaaag gagtaactgt atggaaaaaa tattagtagt
    18001 agaagatgat tctatattaa ataaaactct atcatataac ctaattgaag atggatatat
    18061 aattacttca aaatttacag ctaaatctgc actgaagtct atttttgaat gtgaatttga
    18121 tttaataatt ttggatatta atttaccaga taaaagtggg tttgaattat gtaatgaaat
    18181 aaaggaaaat tacaatatac caataatttt tttaactgct aatgatatgg aatgtgatat
    18241 gattaaaggc tatgaacttg gagctttgga ttatataaca aaaccattta atatcaatat
    18301 atttaaacag aaagttaaag cttttttaaa tcatcttaca gtaaaaacaa aacaagatta
    18361 ctatagggat ggatatcttg aaattaactt ttctgagtta tctgccaata taaatggaaa
    18421 tcaaattata tttacaccat tagaatatcg tactttaaaa ctgcttactg aaaatcctaa
    18481 aagtatttta acaaggaaag tacttttaga aaaactctgg gatatagatg ctaactttgt
    18541 agatgaacat actttaacat ctgttataag taggattaga agcaaaattg aaaaagacaa
    18601 tcttaagtat atcaaaacgg tatatggtat gggatatatg tggttaggtg aaagaaatga
    18661 attttaaaaa attttctttt agttctattt atttaataat tgctgttggt ataattttta
    18721 cagctatttt atttagtatc tcaatttatc taataactga tgatttaaaa ctaattgctc
    18781 tattattaat atatacaata gtactttgtg gatttatagc attaacaata tttttacttc
    18841 ataaaaaaat agttatattt tgttctaaaa tatgtcacac tttagatagt atgatgaata
    18901 gtgaagacaa tattgaaatt gaattagaag aagaaactat tttatcacgt atcaatcaca
    18961 gattaattag aatgtatgaa gttattcaag aaaatcgcaa tagtattgct atagagaaag
    19021 ctgatttaca agaactagtt tctgatatat ctcatcaaat taaaactcct attgcaaatt
    19081 taaaaatgat taatactact ctactaaatc aaacatttaa aacagaaatt caaaaggatt
    19141 ttttaatgga tatggaaaac caattagata aattagattt tttaatgcaa tctatggtaa
    19201 aaacctccag actagagaca ggtataatca cactatctaa aaagaaaaat tcaatttatg
    19261 aaacaattgc tacagcactt agtggaattt tgtttgatgc tgaaaaaaag aatattgaag
    19321 ttacagttga ttgtgaccca aatttatata taattcatga caagaaatgg acttctgaag
    19381 ctatttttaa tatattagat aatgctgtaa aatacacaaa ttctaatggt aagatacatg
    19441 tagctacaga atgttgggtt atgtatacaa aaatagatat tattgataat ggaaaaggaa
    19501 tatcagaaag tcatcaagca gaaatcttta aaagatttta tcgtgaagaa gatgtccatg
    19561 acatagaagg tattggaata ggtctctatc tttcaagaaa aattatatct cttcaaggtg
    19621 gctatattaa agttacatca gatattggaa aagggtcgac tttttctatt ttcttaccta
    19681 ataaataaat ttttaaatat ttcatttgta atgattctgc aacattttgg ttttatactg
    19741 tatttacaag atgttaagga ggtattatta tgagtatttt acaagtaatt aatttaaaga
    19801 aatattatgg acaaagttca aacattacaa aagctcttga tggtgtaact ctatctattg
    19861 aaaaaggcga atttatttct attgtaggta catctggtag tggcaaatcc acattattaa
    19921 atatgatggg aggattagat aatcctacat ctggaaaggt tattataaag ggtaaggaat
    19981 tatctactat gactgatgaa cagcttacaa tctttagacg cagaaatata ggttttatat
    20041 ttcaaaatta taatcttgtt cctttactta atgtatatga aaatattatc ttaccaatag
    20101 gattggatgg agagaccata gataaggatt ttataaatga aattataaat atgctttctc
    20161 ttgaagaaaa attatatgat atgccaagta atctttctgg tggtcaacag caacgtgttg
    20221 ctatagctag agcacttgta acaaaaccag ctattatact agctgatgaa ccaacaggta
    20281 accttgatag tagaactagt tcagatgtac tgagtttact taaagtgaca agtaaaaaat
    20341 tcaaccaaac aattgtaatg attacacaca ataatgaaat tgcacaacta actgatagaa
    20401 ttattcgtat tgaagatgga aaaattgtta actaggaggt gtagtatatg tttagaaata
    20461 ataatcgcac atttataaga aaaatagctt taaatgattt aaaaattaat aaacttaaaa
    20521 catatctttc aggtatcatt ataatgattt ctacatgttt attattaaca gtgaccttag
    20581 tttcatataa tgcctctgta gatttagtta atgcatctcc atatcatgct atatataaat
    20641 ctgtagatga aaaagcaaaa aatatactat ataaagataa aaactttagt ggcgtaggaa
    20701 cttacaaatt aattggaagt aataaaaaga cagattgtat tatgtcgatt gtttatgcag
    20761 atgatacagc aattaaactt atgaattttc aaccattgaa aggcaaacta cctacaaata
    20821 aaaatgaaat tgctatttca gaaaaatatt tacaggaatt tggtttagat aaagatattg
    20881 gagatagcat taaattaaat tattatgatg atattacgaa taaagaagtt caatgtgatt
    20941 ttattattgt tggatttcta gaaaattatt atcaagataa tgccaagcaa tactatacag
    21001 tcgtttcaaa tgattatttt aagaatatag cttctacacc tttacaaaat aaaagtaata
    21061 cttttgacga gtcaagacct gatactgtag atgtattagt taaactatca gaagaaaata
    21121 cagagaaaga ttcagcttca attaagacac agttaaagaa aattggttta tctttaggta
    21181 ttaagaaata taatatatac ttaaatgata actatattga atcaaattta attgatggtg
    21241 agcagattat tacagtttta gtagttggaa tagttgttct tttttctagc gtttttgtta
    21301 tatatagtat tttttatatt tcagttgtta attcagttca gatgtatgct aagttgaaat
    21361 cgttaggtat gacttctttt cagttaaaaa agattatttc tctacaagga aatattttgt
    21421 caattatttt tattccatta ggggttatag cttcttgtat aattgcttac ataattcaac
    21481 cattagcatg gcaaatgata gctgatttat ttataatttt aattttatca ctggtaatgt
    21541 ttttaactgt tagaatttct ttatttaaac cagctagaat tatttctaaa atatctgcta
    21601 ttgaagccat gcaatataca gaaactaaat ttagaaaaaa agcaaaaaat tttagttata
    21661 taaatataaa aaatctagca ttaaagaata tcgagtcaaa tagaaaaaaa aatttgattg
    21721 cattaatatc gctaagcatt agtggagttt tatttatttc aatcgctaat cttgctaatt
    21781 caatagattt caaaaaacaa ctatctcaac aatttgtcta taacgaagat tatataatta
    21841 gcattaagag tgataactta tatgagcata ttacagaaat ccaacaaaat aatccactaa
    21901 cagattctct taagaatgaa attaaatcta ttcatggagt aaaaaaatta attgaatcca
    21961 aatcaattaa aagtaatatt atagaacctt acatcaaaga tagagacgaa aaacaattta
    22021 ttactctaat taaaggtatt acgcctgaac tttcaaaatc acttgaagaa tatattgtca
    22081 gtggaaaaat agactataca catttagatt cagatagttt aattataaat aaatatagaa
    22141 caaaatatta tggattaaat ttaaaagttg gagatacagt tacatttaat atctttagtg
    22201 gaaatgatat tattaaaaag aaaatgaaaa ttataggaat cattgacaat tccaatacag
    22261 gaggtatgtt ttttgcttca gacaaaactt tagaatctct aacaccatat aatacaaatt
    22321 tagatttttc tattttaata gataaaaagc attctaaaga agttgaagaa aagttgttaa
    22381 gtataattca gaaaaattca aatttaatgc tttattcata tgaagatgat tatagaatga
    22441 ttactagagc atttcaatat ataattatag cttcatacat ttttgttggt ttaatttctt
    22501 gctttggtat actaaatatg accaataccc taataaacag cgttttaatt agaaaaaaag
    22561 agtttgcatt acttcaagcc gttggaatga caagaaagca actgcgaaat atgctttata
    22621 gagaaggtct aaacataagt atcaaagcta tatgtacttc aagtatacta ggttattttg
    22681 gttcaaatct actttgcact tttataaaag atgtaattag attagacttt attaatttta
    22741 aattttctat atttactatt ttaatttttt cattcgtatt aattggtata caagttttag
    22801 tgactgaatt acttgtaaga aatatagaaa aaaaatcact tacagaacgc ttacgttctc
    22861 agtaagaatg tatataaaaa atagccattt tttatacaag ttttaatatg attttttaaa
    22921 agctataggg atagaaaatt ttgactttac ataattttct atccctatac ttgtttttat
    22981 tttatacaga tacacttact tatatctccg agcaacatca ccagagacat aaacaagcat
    23041 attccttatt ttctaaatat gtcaattgca tgacttgtaa cccctactaa atcttcacgt
    23101 tcacaagtag caaggtgata ttttaaatat aatgcaaatg catcatcatc catagagtct
    23161 actgcttcac gcatatacaa agccaaacca tctgatgcga cataatgcag tctagttaca
    23221 ttaaatgcag acatcaaatc atcaatgttt tctttacgta caagctcaaa caaatccttt
    23281 ggttcagact tagcagcaaa tgtctgtgga tcaatcaaac ctttttcaat atattcagat
    23341 acattaatat ttcctctatg gaacccctcg tcaatgagac agccatcaga tataacatat
    23401 gcagcaaaaa ccacaccacc aggttttgtt acacgaattg cctcatgtaa agcttgttgt
    23461 ttatcttctt tgttataaag atgatatagt ggtcctaaca gtaacgtaat atcatattta
    23521 ttatctggga aaacagataa atccatagca ttaccctgag taatgcttat attttcattt
    23581 gattgagtat ttttatggaa aacctctata ttatgttcga ctaattccac tgcgtcaaca
    23641 tcatatccct gacgtgccag tgtgtgagaa taacgaccag ttgcagcgcc aatttcaagc
    23701 acacaatcac ctgattttat gtacttatca atgtaatgca tagtagtgag aaattccacc
    23761 attccatgtt ttaatgcaag tcgactatct tcatcataag tattataaaa gtcaattaag
    23821 tattgttttg tttccataat ttcacctctt ctatattagt taataaacat caaatagaca
    23881 aattccaatc tggtttttct tgtcttataa aagctgttaa tatatttttc aacatttttt
    23941 cagcactata tctatctaat gttaattttt ttgttgctgt taagacagct atgccatgag
    24001 tataaagaaa taaatctaaa aatattactt ttgcacattc caaatctatt ccaatgcttt
    24061 ccgaaaaaag tcttgccttt ttttcattgt aaatttcttt ataaaaatca ttcgcctctt
    24121 tcatcatcaa atctaaatca tttataaata acaacttaaa taaatacgtt tcttcttgag
    24181 caaattcaat gtatgaaagc ggaagcagta aataagggct tacactttta gaattacgat
    24241 aattaacaac atactgatta taatattcat atgcaaaagc aagaaattca ttttttaatt
    24301 cattcatgtt ttcgtaacaa gtaaaaattg gtcgagtgga acactgtaat ttacttgcaa
    24361 tactcctcgc atttacagct tcaaatccca cttctcttgt aatatccaag actgtattca
    24421 aaatcatttc ttttgttatc tttactttag gtggcatata tgttcacctc tccattaaat
    24481 ttttataaaa cacatatgtt atataactat agtaacatat caagaaatta tgtcaagaaa
    24541 aagctttgca tttttttgca attcctaaaa cttataaata aaacatgagt tgcaattaat
    24601 ctattaatag ataacagcaa ctcagatttt cctttaaata ctcttctttt tgtctaatat
    24661 ttcatataca caatcttcta ttgaattaat atctttttct tttctttttt tagaatcaat
    24721 taaaatgaaa tacagtataa aacctacagc aagtccccat gttccgcctt tagcagcaat
    24781 tacacctccc ataagtccaa tcaatccctt ctcaacacct gtattacata gctccattga
    24841 tagctttgta cataaatatc cttgaactaa aagtgttact gacaatgcta atggtataag
    24901 aggtgtagca atctgcgcaa ttggataaaa acagataaaa attgctgaaa cccatactaa
    24961 tgtacccatg ccactaaaaa cagactgcat ggcttccttt ccaaccttgt acctttgagc
    25021 aacacttcct gtaagtgtcg cagctaatgg accgcacatt ggtatatatg gagaaaagat
    25081 tgccataaaa atatttctta tcccacttat aacattagac ctatttgaat tgaaatctat
    25141 atattcatct tttctatttt cactttcaga aagtactaag ttttcacctg ttataaaatc
    25201 accaaaggca attatgtata tcataaaagc cattggtatc ccttgtataa ataacattac
    25261 acttggaaaa cctattccaa aaggagatac tgtatttatc agatttttaa aatctactat
    25321 gtaaactaaa ttgtcaaaac taaatctagg aatttctatt tctttactaa atatacctac
    25381 tattaaactc actaaaatag ctgatactac accatattct cctaaatgaa ataaaaactt
    25441 attcttaact tttagagtat caaatctttc agaaaacatt acaaaacaag caaccaaaat
    25501 tcctactgtt atagatatag gataagaatc aaatctccct ttaggattaa actctgatat
    25561 tatagtcgat ataccgacac ccattagtat tccaccttta atagaatttg gtatcttact
    25621 aactaacttt ccagctacac cagttatacc cattaaaata aatattattc ctaaatctat
    25681 ttgtaaagct gttaatgctt gtattctttc aatgcccatg ctgaacttta acaaatatgc
    25741 agttgtaaga gttatagaag ctgtaatcca gccaggtaca actgggtctc ccataaaaac
    25801 atgcaaacag tataatattg agttaatgat agccatactc catgccactt catagggtaa
    25861 tcccaaaatt tgtgtactaa ggccaattgt gcctaaactt gtcatacttg atattatacc
    25921 ttgaatagct tctggtttct caaatctgta atgtataaat ggaattctta tcttaaacat
    25981 tccaaatttt atatgaggtt gttcccttct agcgagtctt tccataactt cactccacct
    26041 ttcaataact cttataagtt tacaacttta taattgttta taaattatca atgtcattaa
    26101 aattagtata taacatgcaa attatataaa caataaatta aatctataaa attgatagat
    26161 tttgtgcata tatagaaaga ccgcttcatt tttagttact taaatcactt aatattagtt
    26221 atttaaatca cttgataaag gttttttata aaattcaata gttctattcc atgattcaaa
    26281 ctgtcctttt gaatttcctt ctacagttcc acctgaagaa aaaatccctc cactcatact
    26341 catacataaa gtctccttta gaggcataat atatggaatt ggtaacggat gacccatatt
    26401 attgtatgtt aataattcta cgttatatgg ataattattt tcttcaaaga tttctaatgc
    26461 ctttaaacaa gcttcataac tattccatat gttatcttct tttccagcaa tcataagtat
    26521 atctgctttg gaattttcta tttttattct agcctctttt ctattctctg ctcttttaag
    26581 acttttctta taagtactat taaatccaaa tggaatacct tttgatatat tttttttctg
    26641 ttcttcaaag aatatatcat tgtctacttt gatatatgga aatggctctc ctttatatga
    26701 ccatgatgaa gtatcatttc cactcatcaa tccattaaga gcttggaaac aataaatgtg
    26761 aggttgtgat actacaacct ttttaatttg ttcatatctt gaagcaagta aaaaggccaa
    26821 ttctccaccc tttgatgtcc catgtacaaa tatttcttta gtactggtaa tttcattttc
    26881 actaatccac tcaaatactt tttcaaaata ttctaatgga acctcttcta atttatctgg
    26941 taacccttct aaagcaaagt atgcaactgt tagtacattg aatcctctag atgcaagtgg
    27001 agctgctaaa aggtctagag cgtctaaatt tccatcagaa ccacctagca ttaaaattgt
    27061 tttattatta gaattttgtt tataaaataa ttttcctata aactcatcag atatgtattt
    27121 tgtggtaata tcttctgatt taaatattct ctttaattca acttcttttc tttcaataga
    27181 agtttcaaat atcatattca taattattgg tttatcaata gatatatttt ctgcaaaatt
    27241 tttaccttca gttttagatt tttccagcga ataaattaac cccatacaat tatcagcctt
    27301 ataagtacct tctataggtt caactaaatc taaatctact tctccttttt catttgaaca
    27361 aaacactcca taagatgaaa attcttctcc cttgcaccat ggaaattcca ttttcacact
    27421 tattttaagt ttagtatttt gaattaagtc cgaaaccata atcttaagtc tttcatccac
    27481 aaatgattct acattgtata catttacttt cataatctat ttctccttat aataattatt
    27541 tatgttttat ataaaacagc tttatctaat gcaacataaa taaattttta aattaagaca
    27601 ccatattgac tatttcattt tatcaacata ttccatattt gtcaacatat tgtctttttt
    27661 agtaatttaa aattatgtag tctatatgaa atccagttga tttttggcta attaaagata
    27721 ggaatgctat taggtttaga atatatatat tcaaaataaa aaaccactca tttaaagaat
    27781 ggtttttaat ataaactatt tgttattaat aaggatattt ttttatttaa atttatataa
    27841 tcgaacatct aatatttaat gtttaataaa attatgcatt tgcaaaagta tatatggcat
    27901 taactcttgc tacatataaa ttctcatcac tacatccaat atatctagca tatttttcaa
    27961 tcttttcttt tgcattttca acatcatttt catcgctctc cattaactca tttatataaa
    28021 tatccattaa tgacgcttta tattctctta tatcatagcc taaaaattca gtcaatctct
    28081 caatttcctt actaaaatct ccatcttctt ttaccaaaaa ttcgtataca tcttccctat
    28141 atggatttaa agttattatt tgttttacta ctttgcattc gtcagccttc ccaataaaac
    28201 catctttata attattaaat aaggcattag atttttttat agattcttca tcaatataag
    28261 aatgtaccgc agttatacga ttttctataa gggcatctac aacagcataa tgaattttaa
    28321 aacaatcatt gtataaataa ttgctcattt tctttattgt cgattctatt tctaagaagc
    28381 tcgcgtggcc atttttttta tttttatttg gtataataaa agttttattc aaattattaa
    28441 aaagtctctt aaaatctaaa tatttttcac aataaacact tttaaaggta tcgatatcta
    28501 tagttataat tccaaaactt actatagtct caattccttt cttaaaagac tcttctatat
    28561 atttttctcc taaacttaaa cctctatcag atatttgctt tagattttga aaactattta
    28621 aacaatctct ctcaaagttt ttagatattt ccaaagcata taatttaaag attttcctta
    28681 tcttattata attatttttt gtatcatcaa atctgataat agctccattt acatcaaaag
    28741 taatcattga gttttaacct ccccattagt ttcatcaata aaataaattt aatataaact
    28801 ttataatcat aatattaaac ttatttatac tataattatt aatttgatga taaaagctat
    28861 tttccttcta aataaaaaat ttgtctaaag tttctaaaaa atttagacaa atcttaggtt
    28921 attactcttt aaattatttt taaattattc caaatacgcc aaataatatt ggtataaata
    28981 tagctggtaa caaattggct acttttatat tcgttaattt aagtacattt agaccaagtc
    29041 ctataattaa taaacttcca gctgctgtca tttctgtgac tacaggatca cttaaaaatc
    29101 catttaaaaa tgatgctccc acacatataa taccttcata caaaaataca gatattgcag
    29161 aaaacattac acctatacct aaagaagcag taaatataat tgaagctatt ccatctataa
    29221 cagattttac aaataaagta tcatgacttc ctgtaagacc actttctaat gaaccaacta
    29281 ctgccatggc tcctatacag aataataaac tagatgatat aaaaccctct gctatagaat
    29341 cttttttatt tcctttagaa aatttacttt gtaaaaaagc acccaactta tttacccatt
    29401 tgtcaatatc tattaattct cctatcagag cacctacagc tacagatatt attgtcacta
    29461 atgtgttttt tccttctagt gctcctgata taccaatgta caatacacat aaagcaattc
    29521 cattcattat agtatcgctt actctttgag gtaatcctcc ttttattata agacctacta
    29581 tacatccacc tgcaattgct agactatttg ctattactcc aaacattttt tctcccctcg
    29641 attagctaat tgaaatttat cctattatta aaacctaaac atctatactt tgtattggat
    29701 attttaaata ttccaaaaat tcttcaaaac cttttctaga tatatttaca gttttagtat
    29761 ttatgttagg atgaaaattt aagtaatctt ctttaattac atctttatct atgtaaagct
    29821 caacttttct ttctgtatca tttattaatg aaaaaggatt tacacttcca ggaagaagtt
    29881 taagtacatt gtatagtctt tcaggtgaag caaacgataa tctagaactt cctatcttat
    29941 ctttaagtga gtttaaatca acttgttttt ctcctttaac tacaataaga taatacttat
    30001 ttcctttggc atttcttaaa aataaatttt tacattgaca cccctttgtt attccatcta
    30061 aaatgactaa ttgctctgct gtatatacag cttcatgctc tactacatca tattcaacat
    30121 ttaatttatc caaaatatca tatattttag tttcattcat gctagattca ttttcatctt
    30181 gttctttttt attatttaaa tcactcatac ttttctcctt aaacacttca tcataatatc
    30241 attgtgaggt attattctac tatagctatt gctcttactg gagctccatc agcatcatta
    30301 tacttaaatg gtgctgctat aaatagaaat ttttctggaa cagtttctaa atttgtaaga
    30361 ttttctatga ttatttttcc tttttcaaat aaaatatgat gcacttcaaa tactgatgtg
    30421 tcatatctat ccactgatag catatctatt cctatgcctt ttatattagt attagctata
    30481 tagtttgcag cttcttttgt taatgtagga taacctacat agtactgctt tttatcccaa
    30541 aattttgacc aacctgattt aaatattata aaatcactat tttttatttc atcttcatat
    30601 ttttttagat attctaattc tatattctca tttccctttt caagttccaa tacataagct
    30661 ttcccaacaa aattttctat atccaactta tctagggtct cacctttagt atacatatgt
    30721 cttggtgaat ccatatgagt tccattgtga gaaaatacac taattaatgt ttcttgataa
    30781 ccattttctt caataatagc tactttcttg atatctggtc tattaggctc tgcatataca
    30841 ggcatgtcat tatgtgtcac atgagttaaa tcaaaaacct tcatctttat atacccccta
    30901 tgtttttatt ttctattata tacctaaatt cattttattt ctatcagatt ttattccatt
    30961 atataccata ctactatata ttttttataa acctcaaggg atttaccgaa aaatcttgga
    31021 aagaattatc agtaaatata acatcttcac ccaaaaaacg tttatacctt ccttcttctt
    31081 tctttaaagt aattctctgt ttttgtgaat gattattaaa aaccattatc ttaagaggag
    31141 gtttttttct attagtctgc actcttttta acatgtattt tatgtgcata tcagcttcag
    31201 gaaatgaata tccacaaaat attaaaaggt cagtatctct taaagttttt tctgtttcat
    31261 tccaaacatt acttaaaaat atgtttgaca tattcttaaa atatgttggt ggcactataa
    31321 taggttctgt taactcacca cactctaaac attttgtctc tgaactattt tcaataagct
    31381 tcatgacacc accttcatgt ggtgtaagag ttacactatt acaaatgggg caataaagcc
    31441 aattcaatga cccatgtatc ttatataatt tgattaatgg ttcttttggt tttctccaat
    31501 ttaactcctc tttaaaattt gtaaactcca caccataatc aagcataatt ggcaaatcat
    31561 tcttatctct taatccagta actgtattgt ctatatgtat atcataattt gcactaataa
    31621 aagtagtatc aagaagcaaa tcattttcca aaagattttc aactaaaagt ttatgatatt
    31681 tattatctgt tctaggtgta ttatgaattg cttcagccat tagtagtatt aaatattgtc
    31741 ttaaaaaacg tatactatca cttctgttat ttagattttc tagtccaaaa tttctaaatg
    31801 cttcttttct ttgttctgct aagtctaaaa gacctaaaac ttcttcaaag gtaggaaaat
    31861 ttgcattatc tatattatct tttactatat caatattgaa catctgttta aagaaaatat
    31921 acaattctct attcattttg gtattataat ttgtgggatt tagtttttta aaatattcgc
    31981 taaaaagttc attttgaata ggtagattct ctgctgctga agctcctgct cctaaaaata
    32041 ttgctatttt catatagttc ctcctaatat aaatattact cctattttta tatccattaa
    32101 atatccatat catttatttt atgatacaac aataaagctg tcttttacta gaaaaaatcc
    32161 tattacaaga cagccttata ttatattaaa tctttaataa ttcgtaaata gaaagagcat
    32221 atatttgagt agcttttata atatcctcta ctattaagta ttcattagct tggtgttctg
    32281 tttctggttt tcctggaaaa atagctccaa atgcaacaca attatctaaa gctcttgcgt
    32341 atgttgctcc tccagatgaa agtggtgttc catcaagacc agtttcttct tcatatactt
    32401 ttctaagtgt cttaacaaga agagtatctt ctggaacata gattgaatcc aagaaatcat
    32461 attcttcata atttaaattg tatttatctg tcattttctt taactctttt acaaaatcat
    32521 cctttttgta tgttactgga atccttacat ctattcctgc aaattctttt tcgttatcaa
    32581 tagttactct acctatattt actgttagtt tacctgatac atcatccttg caattaggaa
    32641 ttatattgtt tccattagca tcttcaccaa taacttctgc taaaaactta attatattag
    32701 aatctatacc tatattatta agagctatac aaagtctagc cactgcattt ataccagtat
    32761 cacttgctgc tgaatggaca ctctttccaa ttatacagat tttattacct tcaacagtat
    32821 attcaaaatt taatttatca agttcttttt ttaatttatc agagtatttt ccaatataga
    32881 ttgctttacc tggaactgca tttaaagcct ttccaactga caactctata tcacttttgc
    32941 tatcacaagt caaatgaact tgtaaaagac ctttctctgc atttgttatt gggaatctag
    33001 aatctggagt aaatccatag tttggtattt cttcattatt ttctttatat ttatttatac
    33061 atctccaaag attttcttca tcagccccaa aaatgaatct tatcctctta ttaaagtcta
    33121 catttaaatc cataagagct ttcactgcat aaattgctgc tattgtaggt cctttatcat
    33181 cttgtgttcc tcttccatac aatttaccat cttctaaaac agcttcaaat ggagggtaat
    33241 tccagctttc taaatcacct tctggaacca catcaacgtg accaagtata cctatcattt
    33301 tttcaccttg tcctatttct gcatatccat aatatccatc tttgtatact gtcttaaatc
    33361 ctaaagattt acataagtct aagatacctc ttaaagcttt atctacattt tcaccaaatg
    33421 gacaattttc agttgcttca gatataacac taggtatttt tacactttct tgtattgaag
    33481 aaatcatttc atcttgtaga gaatttactt tttctttaat ttgctctttc atattatcac
    33541 ccttcaattt tcatcataat atactaataa atattttgac ctttaaaaaa aaaaatatgc
    33601 ttattttttc agttttttta taaattcaat cgcttttaaa gtccccattt ttgaatggtc
    33661 aaatgtaagt ccaccttgaa aataaacatt ataaggaggt cttattggag catctgcact
    33721 taattctata gaagaacctt gtataaatgc tcctgctgcc attatgactt cactttcgta
    33781 tccaggcatg tcccaaggaa caggttttac ataagaatcg actggtgcag cttcttgtat
    33841 accttcacaa aaacttatta cttcatcagc attattaagt ctaatacatt gaataatatc
    33901 acttcttaag tcatcatatt ttggtaatac atcatatcct aatttttcaa aagctcttga
    33961 gcaaaagata gctcccatta cagcctgaga tactatataa ggcgccaaga aaaaaccctg
    34021 aagtacattt ctagttgttc caaaagtaag accacattct tttcctattc caggagaagt
    34081 cattctataa gatataagct caatcaaatc ttttctacca gctatatatc cacctgtcaa
    34141 tgcaagccca ccaccaggat tttttattaa agagccagcc ataacatctg ctccaacatc
    34201 agtaggctct ttggtatcta aaaactcacc ataacaatta tcaaccatta ctatagcttc
    34261 tggtttaaca gactttatta cttctatagc ttcttttata tcactaattg aaagtgattt
    34321 tctccaagaa tatccttttg acctttgtat cataacgagt ttagttctat catttatttt
    34381 gtttttaatt ccttctaaat ctaagtttcc atcctctaaa aaatctacat catcatatgt
    34441 aacaccatac tctttcaatg aacctttttc ttctcttatg cctataactc cctctaaagt
    34501 atcatatggt ctaccagtaa cagataaaat ttcatctcct ggtctaacta taccttgtat
    34561 acataaagta agtgcatgtg taccatttac aattattggt cttacaagag catcttctgt
    34621 attaaatact ttagaataaa tttcctctat tttttcacga ccaatatcat tatatccata
    34681 tcctgtagtc cagttaaagt gcatatcact tagtttagat tcttgcatag cttttaaaac
    34741 tttatattga ttatattctc ttatttcttt tatttcttca aacttatctt ttatttcttc
    34801 cattatttct tgcgatagtt taaaagtatc atcatctatt ccatagtagt cttttaataa
    34861 ttcttttgtc tcattaagca ttttatcacc tgtctcttta ttattttatt taaacatgta
    34921 aaggagacta ttttactaaa acaaataaat tatagtttat aagttagtat aagtctcctc
    34981 tcaatcatct taaattaaat taattatcta tctgttgtta ttattattgt tgttttggtt
    35041 ttgatttgtt agattaatat actttccagg ttgtatagtt gatacagcat gtttataaat
    35101 catgttttgt tgtctattat ccccttctat taatattata taactatcaa acccctttac
    35161 aagcccttta acttgcactc cattaactaa atatatagta acaggtatcc tttctttcct
    35221 tgcattattt aaaaacaaat cttgtaaatt taaaactgta tttttcatta gatttgtacc
    35281 ctcccaagat taaattgaac ttctaaaata ttcctacctt atattctata taagttatga
    35341 caaattttca atattaagtt gtatacttaa aaatttatat attattttat agaatcttta
    35401 atatataaga ttatttcatt ttttaattcg tctatatttt catattggtc taaatcaaac
    35461 cattttgctg ttttatatct tttaaaccat gttatctgac gttttgcata ccttctagaa
    35521 tctcttttaa ttatttcaat agcttcttcg tatgtatatt ctccatccag atactttaat
    35581 atctctttat aacctatacc ttgcattgat atcatatctt ttttaaatcc catacttaaa
    35641 agttttttta cctcttcaac caatccattt ttaagcataa tatcaactct catatttatt
    35701 ctttgataca aatgttctct atctctattt agaactatta ttattggttg atattcttca
    35761 ttaaatttta aatcacttga aaaatcattc attttcttac cacttagaca aacttcaaga
    35821 gctcttatga cccttttagt attgttttta tggattctat tagcagattc ttcatcaagt
    35881 tcttttaact tattatgcat gtaatctatt cccttttcag caagctgttt ttgaagttct
    35941 tctcttaatt cattattggc atcagattgt gcaaaatcca tattatatat taaagagttt
    36001 aaataaagtc ctgtgcctcc agttactaaa acacattttt ccttttcatt tatttcatgt
    36061 atatattttt ttgctctttg ttgaaactct gaaactgaaa atggatagtc aggcttaact
    36121 tcatctataa ggtaatgctt cactccttgc atctcttcct ctgtaacttt tgcacttcca
    36181 atatccatat attcatatat ttgcatagaa tcagctgaaa ttatctctgc attcatatct
    36241 tttgctaatt ttattgacaa atctgttttt ccaacagcag ttggacctgt aagtattata
    36301 agtggtattt ttttcataac attcctttcc atatatttta aatatccaaa tattttacat
    36361 aattctttta aacatttttt ctatttctgt cttagatatt tcgaccatta taggtcttcc
    36421 atgaggacat gtaaatggat tctcacactt ttctagctgt tccaataaac tttttatttc
    36481 aatatcgtat attttatcat ttgcttttat agcagaccta catgccatag atgcaaatct
    36541 ctctcctttt aaatcataat tacttgtaat ttcttctata ttatcaatta tttgaagtat
    36601 aaatttctca gtttcaggta ctccaaatat agtaggaaca catcttacca ttatatgatt
    36661 attgccaaaa atttctagct caaaaccaaa tttcataaat aactccaagt tattttcaat
    36721 ttgaagcata tctacatttg atacttcaat aaccactggg tctaaaagta tttgcatatt
    36781 tatatcttgt ctatagaact tctccatata tctttcatat agtattcttt catgtgcagc
    36841 atgttggtcc aacaaataca tagaatcgtc tttgctcaaa attatataag tattaaatac
    36901 aactccaatt acagaatatc cgtataaaga aaacttgcgt tttgaactac acgagtattc
    36961 ttcttcactg tccttaatac tatctcctaa gtaataattt ccttcatttt taattccatc
    37021 aacttgaaac tcttcttgta tattatcatt tgcactatct tcacttagat aattaatgtt
    37081 ttttacatca tcttctacac ttgcatttag gacttcactt actgattgaa attcatttat
    37141 tggtttttca cttgataaag taacaacttc aatgacttca tccttacctt tagtaatatt
    37201 actcttttta ggagtagatt ctaataaatc attatttctt aatttataat ctgtactttt
    37261 ttctctactg ttaatagcga ttctaggttg tgttttttta tcactataag tagcatactt
    37321 tccaataaga tttgagtgta ttaatttaac ctttaaaaaa tctctaagtt ctatatacac
    37381 ttcttgttct ttttcaaatt taatttcaag tttattgggg tgtatattta catctataca
    37441 tgatgggtct acttctatat ttaagaagca cactgcatgt ttacctattg gaattataga
    37501 cttataactt tctgttattg catctatgat tattttactt tttacaaatc ttttatttat
    37561 atagatatgt tgtaagtttt tatttgaacg gtatatattg ttattaccta tatatccatt
    37621 cattttaaag tgattgcact taaactctac atctattata ttttccgtta tttcttttcc
    37681 atatatactt ctaatagtgt ttacaagttt tccatcccct ggagtattta gcatctgttt
    37741 attgttattt gtatatttaa attgaatgtt tggattacct attgcaagtt tatttatcaa
    37801 atcacttatg tttatagttt ctgcatgagt agattttaaa aatttctgtc ttgctggtgt
    37861 attaaagaaa atatctttta taatgatggt agttccatta gtagaaccta ttggttcttt
    37921 cgatattatt tttccacctt caacatatat tttagttcct attatttcat ctttagtttt
    37981 agtcgtcatt tctaattttg atacagctga aatagatgcc aatgcttctc ctctaaaacc
    38041 aagagagtat aaatcataca aatcatcaat ttttttaatt ttactagtag catgtctcaa
    38101 aaatgatttt tcaacttcac ttgaaggtat tcctattcca ttatctgtaa tcttaattag
    38161 actttttcct ccatcaatta tatctatgga aattttattt gcacctgcat caatggagtt
    38221 ttcaataagt tcttttacta cagaagaagg tctttctaca acttcacctg ctgctatctt
    38281 atttatagtc aaatcatcta ggatgttaat tatatttttc atttttacac ctctaagatt
    38341 ttatttcttt tgcttttctt tgaagattat aaagagagtt tatagcatct aatggagtca
    38401 tatttaaaat atccagattt aaaatttctt ctgatagtat atctctattt acactatcaa
    38461 aagagatttg agttaaggct acttctttta cagaatcctc ttgattaatt ttctctttat
    38521 catcattttg cttcattaaa gcaacttcat catttaatgc tttaaattta gaatttaatt
    38581 tatcataatc cttttttata tgtttgtaat cttttactat aagttcatgt tctattttta
    38641 gagattcata tttattctta aaattacttt gatttacctt aactaattct tcgtccaaat
    38701 tactattaat tatattattg ttttctttat ctccatttat tgcaacactg ttgtaaacat
    38761 gatttttttc caagtcttta agtatatatt ttgctctttc tatgacttcg tctggtaatt
    38821 tagctaattt agcaacatat attccataac tcttgtctgc tccctgagga attatttttc
    38881 ttaaaaatat tattccttcc ccatcttctt tgactgctat tgaataattt ttaacctctt
    38941 taaactcttc ttctaaatca gtaagttcat gataatgtgt tgcaaataat gtcttacatc
    39001 taatattttt ttgaatatat tccactattg accatgctaa acttatacca tcataggtac
    39061 tagttccacg acctatttca tctaatataa ctaaacttct ctctgttgca ttttttaata
    39121 taagggatac ttcgttcatc tctaccataa aagtagattg accttgagat aaatcgtcac
    39181 tagctccaac tcttgtaaat attctatcta atattggaat atcagcagac tctgctggta
    39241 caaatgagcc tatatgtgcc ataagagcta ttatagcagt ttgcctcata tatgttgatt
    39301 tacctgacat attaggacca gttattatgt taataatgtt ttctccacga tttaaataag
    39361 tatcatttgg aacgaaattt tcctctccta ctatattttc gacaacagga tgtctaccat
    39421 ttcttatatc aagtttatta ttttcattta ttgctggttt tacgtagtta tttatatgtg
    39481 caactgttgc aagggacaca aaaacatcta tattagctat agtcttagcc actttttgta
    39541 ttctatctat gtttttatat attgtatctc ttatctctac aaatatctcg tattctaaag
    39601 atttaatctt ttcctctgca tgtagtatct tttcttctat ttcctttaat tctggagtta
    39661 tatatctttc tgcattacta agtgtttgct ttcttatata tgtctcatct agctttgcct
    39721 gtttaaagtt agcttttgtt atttctatat aatatccaaa aactttatta aagcctattt
    39781 ttaatgattt aactcctgtt ttttctcttt ccctgttttc tatttccttt acaagaaagg
    39841 ctccattctt agaaatctct cttagttcct taagttcatc actaaaatct gatttaatta
    39901 tgtttccatc ttttatggtt atcgtaggtt cttctagaat agcttcatct attaaattgt
    39961 atatatcatc taatttatcc atttctgaaa catactcttt taggattttt gcatttgata
    40021 aatttatagt atcttttaaa ttaggtaact tttctatcga attttttaag tgaattaact
    40081 cttttggtgt tactctctca aatgctatct ttccacatat tctttctata tcgtatatat
    40141 ttttaagtat atcatttagg tcttctctta atataaagtc atcttttatt tcttctatta
    40201 catctaatct attttcaatt ttagatttat ttatcaaagg ttcttctaca tattttctta
    40261 aaagtctacc tcccattgct gtagaagttt tatcaagtac gtgtaataat gaaccttttt
    40321 tcttattccc tcttatagtt tgagtaagtt ctaaattagt tctagtaaac atatctaaaa
    40381 ccatatattc tgatgaattg tatatattta tattattaat gttagatgtt atttgttttt
    40441 gagtattgta tatataattc agaagaattg ataagcttga ctttattaga cctttatcat
    40501 caaactttag tttttgtaga taaacatctg gaaaatattc ttttaatata tttatatcca
    40561 aatagttatc actaaaactt tcatttatgt atatattact tacagtagct atatctctaa
    40621 gcttttctat aaagtctaaa tcatttataa ttatttcagt tggatggatt tttgcaattt
    40681 cttcaattac cttatcttca tttaaacatg ttgcattagt ttctcctgta cttatatcaa
    40741 cataagttag acctatatta gtaccatcct tatacaaaga taataaataa ttattctttt
    40801 tattttcaag taaatttcca tctaaaactg taccaggagt gatgaccctt ataacctctc
    40861 ttctaacaat tccttttgct gtagatgggt cttccatttg ttcacctatt gctactttat
    40921 atccattttc aactaatttt gatatatatg aattggctga gtggaaagga acaccacaca
    40981 taggagcacg ttcttctaaa ccacaagctt ttcctgtcaa tgctatttca agagcttttg
    41041 aagctactaa tgcatcttca aaaaacattt cataaaaatc tccaagtcta aaaaacagta
    41101 tacagtcttt atatctattt tttacttcaa gatactgttt catcatagga gttaatttat
    41161 tcatatctat ttgcattatc aaacctcctt cttttctaat taaatattat atcatagtag
    41221 atgattatta ttaacacaat atataaaatt ttgacatata actaaaaaca atccaaaatg
    41281 tatactcaca ttttggattg ctaagtttaa tgcttattaa ataaaaatat ttttttttac
    41341 aataaagata ttatttcttt tttaagttta atgatatttt caaggttatc ttcatttaac
    41401 tttctactat ctataacaaa ttctttcttt actattgatg gtttttttga aataacataa
    41461 attctgtttg atagcattat agcttcgtca atatcatgag ttataagaag tattgttgaa
    41521 tttacttttt tcttaacatc taaaagccat ttttgcatgg atgttttagt taatgaatca
    41581 agtgccccaa aaggctcatc taaaagcatt atgtcattag aatttataaa agttctcaag
    41641 aagttagccc tctgtctcat tcctccagaa agttctgaag gatatttatc ttcatatccg
    41701 cttaatccaa acacctcaaa ataaggtttt accattgacc tagctttact ctttttttct
    41761 ttttttaaaa ttagtggtag tgacacatta tctattatag ttttatatgg caagagtaaa
    41821 tctttttgat acatataact atacttacca tttatattca ctttgccact atcataatct
    41881 gtaagtttag ttataatatt aaaaatagta ctttttccac atccacttgg ccctaatata
    41941 gaaacaaact caccttcata aacatcaata cttatatctt ttaaaacttt aatatcttta
    42001 taagtttttg atacattttc tatagatact tttacttttt tattgtggta aaaattcatt
    42061 tgtgtaagca tcacttgcct tcatatcctt atctattaat ttatattctt ttaagaatga
    42121 tgtatagttg ttccatacac tatctttcat ttctccccat cgtggtgcat catctttgta
    42181 cttgcttgct aaatattctt gactctttaa agctagtttt tcatctactt caggtgcatg
    42241 ttttactaaa atttttgctg attcttctgg attttttatt gcatattcat aaccttttgt
    42301 tgtagctttt aagaattttt tagcaagctc tggattatct ttaagtacag tttcattaga
    42361 aattataagt ggtgtataat aatccaatct ctcatctaaa tcttttactg gtataaagtt
    42421 taagtcatat ccaattaaat cagctttaac tgcatcccaa ccttcaaata tccatgcaaa
    42481 atctacagtt ttcatagctg caaagaaatc atcttgacca gtattaacta tctttaactt
    42541 attaaaatca gctccatttt tcttcataac tgctttaaaa acagcttctt ctgatggaga
    42601 gccccaacca ccataagttt ttccttcaaa atctttagct gttgttatat tcttttcttt
    42661 tggtgatgca aacccagaag tattatgttg tataacagtt gctacagctt ttattggaag
    42721 tggatcttca ctagtctttg cataagtaac ttgttcttga tagcttatac caaagtcagc
    42781 ttttcctgtt gctactaaag tttctgctcc actttcaggt ggttgtacta tttcaacatc
    42841 caaaccttct tctttatagt aacccttatc aagtgctaca aataatccag tatgatttgt
    42901 atttggtgtc caatcaagca ccatagttac ttttttagaa gaagtatctt tatcattgtt
    42961 tttgtcttta ttgttatttg aagaacatcc agttattgtt gccaatgtaa aaacacttac
    43021 taaacctaat attcctaact ttttaaaatt cataattgcc tccctcaaat acctttaatc
    43081 tattaatcta tgtcttataa caactttttt tacagcctgt acaattccta caaacattaa
    43141 actaaatata actactaata tagtagatgc aaatacttta tcaagtgcat atgcactttt
    43201 tgacctaagc atataaacac caagtccttt cgttccacct agccattctg caacagttgc
    43261 tgccattaca gcatacgttg cagatatttt aagtccagaa aaaaatttat ccattgccat
    43321 aggaaattta aggtgaatga atgtattaac tttatttgag tccatagtct taaataaatt
    43381 taaataatct ttatcaatat tctcaatgcc atctacaaaa cttattaata taggaaaaaa
    43441 acaagtaagc attaccatca atacttttgg cattgttcca aatccaaacc atatcataaa
    43501 gagtggtgct ataattattg taggtatcat ctgtgtaacc aacataatag gataaagaca
    43561 tttttttatt attgatacaa aatccatcaa tattccaatt accaatgata ttataattgc
    43621 gactataaaa ccaagtattg cttctcctat agtaaccaca gcatgcatgg ataaattttg
    43681 ataatcttta aaaaacacat taattatatc tactggtgtg ggtagtatat actgaggaac
    43741 ttctaaaact cctaccatag attgccaaag aataagtata aacaaaaatg ttgctattgg
    43801 atatatacta tctttgactt tatctatgat ttctaagttt ttcatctata gtcagacctc
    43861 cagctttttc atctactcta gctactgtta tgactctttc acatccaaga ttaaaaggga
    43921 ttttatgtac cttttttaat aattcaaaaa cttcatcaaa atcaccttca acagtagtgc
    43981 tcattgctcc tatttcacat ttaagaccac ttttttcaat ttcagcaata caagcatcta
    44041 ctactttata catctcttct tcacctttgt aaggtcttag tggcattact gctatgtctg
    44101 cgattaccat ttaaatcact cctttaaaaa taattaatac ctactaggta tattttgttt
    44161 tttattaaaa aattttatta ctaaaaagat attatattta aataaaagaa aagtcttatc
    44221 caaaatagga taagacttat ttttatctta actggtctcc ctacactggc attatccaaa
    44281 caggttcaaa gggtcgagat aaaatctcct ctcagcacat tagctccccg aaatatatta
    44341 tatcttttct acttgattat actacactta tcatatttta acaaattttt tatttatatt
    44401 agatatttta tccgttcaaa aatatctaat ataaattgta cattattaca ccaaataaat
    44461 tatcttaaaa tgctaattta tcaacatctt ccaaaactag attaactgaa ttttctagtt
    44521 tttattttgc tatttcaagc atatttggat gtatatcaat tccatacaaa tattgtgcta
    44581 aatttctgtt ttcactcatc taatttgcaa tcgttacaga ttacagatta gaaatagctt
    44641 ttagactcta cttatcttta tctacaaaaa atccttcaat aaattcagta ataatattca
    44701 gtaatctaaa aataaacctc tatctagatt tttaagatac aagcctttta ataagtacct
    44761 tttgtgataa tataaaaatt actcgtcatt atcatcaaaa tcctcagcaa ccaacatttt
    44821 agataagaat caaactctat aatataatta ttttatccaa tttatttttg agaaataaaa
    44881 tattttttta atttttaaat tttttaatat gcaccttgaa aaaagaaacg ttttcctata
    44941 ttatggtaat agtagaataa aactaaatag gcaaaactag agaaatttag tgacgcaaag
    45001 ctatagggac taagacttat gaaatgagtt atgtcagcca gttgccaaag agatattttc
    45061 tttttgtttt tatgaatgtt ttttaggggg atatatgata tatgtttatg gataaaatgg
    45121 atagatgtac acatatacta actgcatata tatgcagttc acgcgattac tgcaatttta
    45181 tagatacaca attaaatgat tttatactag aatatggaga gaatgtggta gaatcttgtt
    45241 tgcatcaagt gatggtattg gtaagcagat ataattaaag aaattttatt ttctagaaaa
    45301 ccctttttag ttttatctac gttttataat tcattaaaga actaattaaa ataagcttca
    45361 ttatatattt ttcatgaagt aaacagttga gtttatctca tatactgttt accccaatta
    45421 cataattcta ataatataga ttccaatgat ttaccacgtt tagtagacaa atattcaact
    45481 tttggaggaa tagttggata agaaatcctc ttaataagtc aatctctttc aaaatacttt
    45541 aattcttgtg acagtatctt atgacttata tgaacaactt ctttttttaa ttgactgtaa
    45601 cgtattggct cttgttttaa aatatgccat aaaataattg ccctccattt acttcctatc
    45661 acagtcatgg taaaaccaat tgaacaatta aaatcttttt gtctttcttc aatatttgga
    45721 aattcttcaa aattattatc tatatccatc tcaatcctat ctttcaaaat agtaagtatc
    45781 taactaaaaa gtgcattctt gtttagcgta ctaattcgta atataatctt gattgtagta
    45841 tagagcctta cataatacta cttttttaga tgtatatgtt taaattttaa tatagacata
    45901 ggttatttta ttaattttat ttaaacagat aataataaat aataatttat ctcaagtttt
    45961 ctatgtagat aaactaatct aatgtttaga aaggattata taatatgaat aaaaaatttc
    46021 gtctttatca agttgactca tttacaaagg aaaaatttac aggtaatcca gctggtgtaa
    46081 ttacaaatgc tgatggctta tctgaatcac aaatgcaaaa aatagcaaga gaattaaata
    46141 attcagaaac tgcttttatt ttcaataact tggctaaaaa tcatcaagaa aattatgatg
    46201 tacatatcag attttttaca ccaactaatg aggttcctat atgtggtcat gctactattg
    46261 ctgcccatta tgttagagca gtagaaaacc aattcaataa caaaacagta tttcaaaaaa
    46321 ctggtgctgg aatattacca gttgatatta taaaaaaaga taatgattat gaaataatta
    46381 tgacacaagg aaaaattgaa gtacctccac cattacaaca aacctatcaa aaaagattac
    46441 ttaatgcatt tggtatttta aagaaagata ttcgtacaga ttgtcctatt gccatatcat
    46501 ctacaggaca ttcaaaagtt atgattggaa taaaggaatt atcaacatta aatagtttat
    46561 ctccaaattt atatgaatta tcgaaaataa gtcaagaaat aaaatgtaat ggacattata
    46621 tttttacatt acataataaa gaaactctac aagttcatgg aagaatgttt gctcctgcaa
    46681 ttggtatttc agaagaccct gttacaggaa atgctaatgg acccttaggt gcgtaccttg
    46741 tacattataa agtaatacct acacccaaca cagagtttat atttgaagca gttcaaggag
    46801 aagcaataaa acgcaaaggc aagatgttag taaaagtaat tattttagat aataagccag
    46861 ttgaagtaaa aataattgga aaagctgtaa ttgcattctc aacaaacata gaaatctaat
    46921 tatagattcc ttctaagtaa atttttgaac tttttaatac taatttaata acaaactaat
    46981 ttatatacaa tcaaattaat ttttttatta tttgttaata tatatttatc attatattat
    47041 ataataatat agatagttac tatatcttat aattagataa atcataatta tatattattg
    47101 ttaaaactca attatataat ttttaataat attattttag gaggtaaaaa tgataaacga
    47161 tattaaaaat aaattcaaaa attacaaacc atatataaat ggatacaaga atatgaagag
    47221 agcatctgtt ttaattccaa tagtagaaat aaataacaca cactatatat tatttgaagt
    47281 tcgctcaaaa aatttgaagc atcaacctag cgaaatttct tttccaggtg gtaaaataga
    47341 atcaggtgag actccatatg aagctgttat tagagaaact tgtgaggaac ttggaacttt
    47401 tagtgacaat atagaagtaa tatcaagtct tgacctcctt ataacaccag taaagtttat
    47461 catacatcca tacttaggat atataaaaaa tattaataat ttaaatataa acaaggatga
    47521 agttgaccat acttttttgg ttcctataaa atatctttta gagaatcctc caaatactta
    47581 tagtaatact gtaaaagttt ttccagatga aaatctacca tatggttcaa ttccaaacca
    47641 aaaagattat aaatttgaaa gtggaagtta tcctattctg ttttataaat ataaagatta
    47701 tgtaatttgg ggaatgacag caaaaatact agaaaacttt ttaaattttt tatcagaata
    47761 acactcataa taaatcatca aaacttttac ataagaaatt tataaaagtt tctaaattta
    47821 acaattctaa aatatcaata actatatttt gtagcacttt tttattttat tattgtttga
    47881 atatttgatg gttttcaatg caatttcaac ataaatacta tgtattagtg tatactgttg
    47941 atgaattaaa gtatgataat ctatttaata aagtatgaag taaatgattt taatgtgtct
    48001 ttatggtaaa attactaata agtaataaaa ttaattaaaa tatatggagg tgcttataat
    48061 gtttgctgta ggatttgttg ttataattgc acttgccttt ttcattttaa gtgtactatt
    48121 atttaatgga aaagccagta tgctactagc aggttataac tctatgagta ataaagaaaa
    48181 agcacgatac gataaaaaaa aattatgtag aagttctagc attgttactt ttattgtctc
    48241 tataatgcta tttattatgg cgtttttggg atatagaata gagagtggtc aaatggacga
    48301 aaaaaaaatg gttccctttt ctataatatt tataatagtc atactttcca gtgtattttt
    48361 taatatcctc tactctaaca aaaaatgtaa aaaataaata gttgtaagtt gagcagttaa
    48421 ttataaaaga ttgactgctt tttcatgtat attgactact cttattaaat attttaacat
    48481 ttaaaaatct atgtaaaaat aatgaatata gtacaaactt ctaataatga ttttaccttt
    48541 gtggttacag tccactatat ataatttaat atgataacag ggaattacta atgacaacta
    48601 agtaaacttt tataaaatat aataaaacaa aaatagatgt acaatgaaat tatatcttat
    48661 atcaaattta tttttattaa tagcaaaaac ttacattagt ataacatatg acaaattcgc
    48721 ttaaaataaa aatttttaat ataatttgtt ctatagtaca tctattttga ttagtttgca
    48781 taattttatt attttgtaca atattaatta tttactaata tcccatttaa tgaaaaagtt
    48841 ctaggttcag taattttgac cataactaat ttaccaatta aatcatcatt tccaccttcg
    48901 aaatttacga gtttattttg tctagttcta ccagcaaact tattttcatt atttttactt
    48961 cttccttcaa ctagaacttc aactattcta tctttatatc catcatttat ttctgcagaa
    49021 atcctattta cagcttctaa caccctatta aatctatcat gctttatatc ttctggtatt
    49081 tgattttcca ttttagcagc aggagttccc tgtcttttag aataaataaa tgtaaaagct
    49141 gaatcatatc taactttttc aaccacatct aaagtgtcca ataaatcttc ttctgtttct
    49201 cctgggaaac caatcattaa gtctgtagaa aaagcaatac ctggaacttc ctttttagct
    49261 ttttctatta tttctaaata atattccttt gtataatgtc tattcatttt tttcaaaagg
    49321 ctactgcttc cacattgtat tggtagatgt aaaaactcac acaccttatc acaatctcta
    49381 attgcgtata ttacttcatc agatatatct tttggatgag atgtcataaa tcgaaccctt
    49441 tcaattcctt ctatatcatt cacttttctt aaaagttctg agaatgaaac tggattttca
    49501 agtgtcttac cataagaatc tacattttgt ccaagtaaag tgatttcttt cgttccattt
    49561 gcaacaagct cttttatctc gttaattata tcttcaggag ttctacttct ttctcttcct
    49621 cttgtgtatg ggactataca atatgtgcag aaattattgc atccatacat tatatttaca
    49681 aatgctttta attcaaattt tctattactt ctaagacctt ctattacttc tccatcaaca
    49741 tcccatacat ccactaacat tttgtcagaa tttattgatt ctgtaagtaa ttgcggaaat
    49801 ttatatagat tatgtgttcc aaatataagg tctacatgtt tatatttttt tcttaattcc
    49861 tctacaacat gtggttgttg catcatacat ccacatacag ctattttcat atctggattt
    49921 tttcctttta gatgttttaa ttgtcctaag ttaccatata cttttagctc tgcattttct
    49981 ctaactgcac aggtgttata tattattaaa tcactttctt caaccatcat tgacatttgg
    50041 tatcccatct cttctaacat tgaacataat ttttctgaat catgttcatt catttgacac
    50101 ccgaaggttt gagtaaacac gagttttctc tttccagttc tgttgaagta ttcttcattt
    50161 tgtctgtgta tttgttctat atatttatct tgttcttgta ttttctctat aggtattgtt
    50221 acttgttttc ttttgctcac gtctattcct cctagttaat ttcttatatt acacataacc
    50281 ttaattatat caaataagaa aaatctttta aagatattat tatttttcta gttgtgtttt
    50341 aatagtaaat ctaatgattt atatatacta tatttctaaa atataaaatc atataattat
    50401 tataataata aaaagatgtt ttaaattaaa acttaaaaca cctttcctta aataaaatat
    50461 atgatttact attaaataca attacatcta ttcattttca attaaataac aatcatttaa
    50521 tattaaatat tgaccttcct caaccgttat atatcttctt cctgaaaaag tatcattagt
    50581 aactattccc tctgcattac ctaagctatc atttctaact tcataatatg catcagaaga
    50641 atttgacatt ataatatatt ctccagcagg aatttctaat ccaattttat acataccatt
    50701 tccaaactta ccattcttgg ccttctgggc tttagcatac tttgctaatg tcattgttga
    50761 atcctcaatt ttaatatatt gaccattctt taaggtgata tatctagtcc cactaaaaat
    50821 atcatttgaa agtatactat cagcattacc tgtactatca cttgtaactt cataataaga
    50881 agcataactt cctgagtttg aagttattaa gtattcacct gctgagatat cttttccaac
    50941 cttatacatt ccatctttta tagtctttgt agtaggttta acatttttta caaccccagt
    51001 attaatatct ccaattccat ttgttatatt taaacactgt tgtactatat ttgaatctat
    51061 atatcctata gaagttatct tcttagcatt ttttaaaatg cttttattgc taccatcatt
    51121 aactaaaacc attggaccat gttttgataa agaagatcct acaagtgcat ttgttaattc
    51181 ataagctcca gctatataaa actctctagc atccttataa aacttattta ttattgcttt
    51241 attagtttca aaacgagtac tcccccctag tctagtagat ttagtattgt ttactaaagt
    51301 ggtactcatt gaagctgttc ctcctattac ataagacttt aaaccactag ttgaaaaagg
    51361 tatactttgt ccattagtaa gaattattgg tgctttatct cttgctgcta cagatgcaat
    51421 acttatagca tctgcttctc ctttatatgc attggttagc ataacagtat tgactttttt
    51481 tattgaattt atttcttttg caacattata acttgttttt attctgtcat ttcccttaat
    51541 tcttacaact ttcattttct tagattttaa tgaattttcg acagatgtac taatagaata
    51601 tgttcctcca attatataaa cttttgatac attttttaat cttgcagatg tctcagttgg
    51661 tatagtattt ttttcagtta atagtatagg ggcatttaaa gctcctgcta gtccacttgc
    51721 acttaatcca tctgcaatag agttactagt attaattaat atagcagttt tatatgcatt
    51781 tttatctgct attttacctg cgatttcata cttatttttt ccttgtattt tttctacaga
    51841 tgatattgca tctactaatt gaatatttgc aaatacaaaa gaaatactta aagtcaatgt
    51901 taatattctt ttatagaatt tcataataaa attgtccccc tcataataaa tttttaatat
    51961 ataaatacat attcttaaat tagttatgta cttaacaaac ttatgta
//
LOCUS       DAMJXI010000022        51347 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.023, whole genome shotgun sequence.
ACCESSION   DAMJXI010000022 DAMJXI010000000
VERSION     DAMJXI010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 51347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51347
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.023"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            27..101
                     /locus_tag="PC465_001690"
     tRNA            27..101
                     /locus_tag="PC465_001690"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..200
                     /locus_tag="PC465_001691"
     tRNA            116..200
                     /locus_tag="PC465_001691"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            210..293
                     /locus_tag="PC465_001692"
     tRNA            210..293
                     /locus_tag="PC465_001692"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:244..246,aa:Leu,seq:tag)
     gene            317..391
                     /locus_tag="PC465_001693"
     tRNA            317..391
                     /locus_tag="PC465_001693"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:349..351,aa:Gly,seq:gcc)
     gene            416..492
                     /locus_tag="PC465_001694"
     tRNA            416..492
                     /locus_tag="PC465_001694"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:450..452,aa:Arg,seq:tct)
     gene            502..577
                     /locus_tag="PC465_001695"
     tRNA            502..577
                     /locus_tag="PC465_001695"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:535..537,aa:Gln,seq:ttg)
     gene            586..661
                     /locus_tag="PC465_001696"
     tRNA            586..661
                     /locus_tag="PC465_001696"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:619..621,aa:Lys,seq:ttt)
     gene            664..752
                     /locus_tag="PC465_001697"
     tRNA            664..752
                     /locus_tag="PC465_001697"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:698..700,aa:Ser,seq:tga)
     gene            756..831
                     /locus_tag="PC465_001698"
     tRNA            756..831
                     /locus_tag="PC465_001698"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:789..791,aa:Phe,seq:gaa)
     gene            838..911
                     /locus_tag="PC465_001699"
     tRNA            838..911
                     /locus_tag="PC465_001699"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:872..874,aa:Met,seq:cat)
     gene            926..1002
                     /locus_tag="PC465_001700"
     tRNA            926..1002
                     /locus_tag="PC465_001700"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:960..962,aa:Ile,seq:cat)
     gene            1020..1096
                     /locus_tag="PC465_001701"
     tRNA            1020..1096
                     /locus_tag="PC465_001701"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1054..1056,aa:His,seq:gtg)
     gene            1105..1180
                     /locus_tag="PC465_001702"
     tRNA            1105..1180
                     /locus_tag="PC465_001702"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1138..1140,aa:Lys,seq:ttt)
     gene            1188..1261
                     /locus_tag="PC465_001703"
     tRNA            1188..1261
                     /locus_tag="PC465_001703"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1220..1222,aa:Cys,seq:gca)
     gene            1269..1345
                     /locus_tag="PC465_001704"
     tRNA            1269..1345
                     /locus_tag="PC465_001704"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1303..1305,aa:Arg,seq:acg)
     gene            1358..1433
                     /locus_tag="PC465_001705"
     tRNA            1358..1433
                     /locus_tag="PC465_001705"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1391..1393,aa:Val,seq:tac)
     gene            1509..1922
                     /locus_tag="PC465_001706"
     CDS             1509..1922
                     /locus_tag="PC465_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649006.1"
                     /translation="MYIVIGNEIVDSEELKIIIDKNSEFKVEKDLSKSTKREDVIAYQ
                     LSIDLNYLDSLINEQCNLASLSDEEKFDEYMTLSDELALDLEELMPKYTIINARAYKL
                     DEVYGIVKIILAVAYADLGHLKLSDVVKRLSRQVD"
     gene            2231..5662
                     /locus_tag="PC465_001707"
     CDS             2231..5662
                     /locus_tag="PC465_001707"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HDF2649007.1"
                     /translation="MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLF
                     RTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEEN
                     GITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
                     IKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQIL
                     GDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLEDKVRKEICEDAVKLSKHVGYSNAG
                     TLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKS
                     QDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPH
                     YDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTK
                     FIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKSEG
                     SKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQ
                     KDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPD
                     NVIEEFTKESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKT
                     KTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNVKAPIHLHTH
                     DTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGY
                     DELGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVK
                     EKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCK
                     GMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLNEKYDINANIRNV
                     ISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEI
                     GEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKI
                     MVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK"
     gene            5904..7832
                     /locus_tag="PC465_001708"
     CDS             5904..7832
                     /locus_tag="PC465_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDF2649008.1"
                     /translation="MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDK
                     VNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGT
                     EKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLH
                     NVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGI
                     QRGDIIPVICGSTINNIGTKEILDTISSYLEPIFTEESKPFRGLVFKTMVDPFVGKMS
                     YIKITEGALSKDKDVFNINKNVKEKIANIYTLRNSELVEIEKAKAGDIVVITKVNSLK
                     TGDTISADKDAEALEKIDFPKPQIYYAVTPKNKGDEEKVASVLNKLVEEDPTLHWYRN
                     TETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGTADVQGKHKKQS
                     GGHGQYGDVKIRFERCESDFEFTEEIFGGSVPKQYIPAVEKGLKDSMQKGILAGYPVT
                     NIKATLYDGSYHDVDSSEMAFKMAASAAFKKGMEEAHPILLEPIMKLKITVPEEYMGD
                     VMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERY
                     GEVPSQFAEKIIGLATAK"
     gene            8285..8749
                     /locus_tag="PC465_001709"
     CDS             8285..8749
                     /locus_tag="PC465_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HDF2649009.1"
                     /translation="MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVL
                     TTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGSQISYKKAKELLEG
                     LKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE"
     gene            8756..9250
                     /locus_tag="PC465_001710"
     CDS             8756..9250
                     /locus_tag="PC465_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HDF2649010.1"
                     /translation="MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLD
                     MPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNAFSSQVNPM
                     LQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLK
                     GSID"
     gene            9266..10291
                     /locus_tag="PC465_001711"
     CDS             9266..10291
                     /locus_tag="PC465_001711"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HDF2649011.1"
                     /translation="MKENIVMKSRVRLARNLNNYPFPNKLDKECAMEIIEKVKNAFIN
                     SNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAENDKSAVIVKKDKTISIMINEE
                     DHIRIQTICDDLNLEYAYSVANEIDDLLESSLEYAFNTKLGYLTSCPTNTGTGMRASV
                     MMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNII
                     ENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRVMSSAEAMSHLSNI
                     KMGIEMNYIDKLDLRAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRG
                     GMNCELQ"
     gene            10278..12725
                     /locus_tag="PC465_001712"
     CDS             10278..12725
                     /locus_tag="PC465_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HDF2649012.1"
                     /translation="MNFNRFTQRAKKAIDLAFESAKSLGHNIVGSEHILLGLLREEEG
                     IAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNY
                     IGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQ
                     NQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVG
                     KTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKN
                     GNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDS
                     ALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRY
                     LPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRD
                     EQGLLKKQLEDVRERWNKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLE
                     EILHNRVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEV
                     QFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEI
                     EKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAK
                     GDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQ
                     ERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKG
                     SNVVAKVKDEKIVFETK"
     gene            12905..14278
                     /gene="radA"
                     /locus_tag="PC465_001713"
     CDS             12905..14278
                     /gene="radA"
                     /locus_tag="PC465_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HDF2649013.1"
                     /translation="MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKK
                     EVFIIDKSSSKPVSINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKS
                     TLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSENLYIFAENNLSIIESYL
                     ESVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKE
                     GSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDN
                     PSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGM
                     LLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDEDIAVTG
                     EVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVVKETKGIEIWPVDNLRQAIN
                     IVLGRNQ"
     gene            14281..15351
                     /gene="disA"
                     /locus_tag="PC465_001714"
     CDS             14281..15351
                     /gene="disA"
                     /locus_tag="PC465_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA integrity scanning protein DisA"
                     /protein_id="HDF2649014.1"
                     /translation="MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATN
                     EDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSE
                     TGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLE
                     KYKTVLDQAVTNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLV
                     SMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSG
                     FSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEI
                     RATYIKNGLIKMKQLVLLDRHI"
     gene            15440..16534
                     /locus_tag="PC465_001715"
     CDS             15440..16534
                     /locus_tag="PC465_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HDF2649015.1"
                     /translation="MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAA
                     VVAGIIIAILGYLIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLL
                     SGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKE
                     NKKEVKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKR
                     VRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNK
                     VAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGG
                     RKYMNETIKVLVTSVLQTPAGRMIFAKPKN"
     gene            16663..18840
                     /locus_tag="PC465_001716"
     CDS             16663..18840
                     /locus_tag="PC465_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649016.1"
                     /translation="MRKKIISFLATFIIILTSASQYSFADDISTRGKVIFIDMNRTSM
                     SNMLRIKSLREELDNRGYIGLMNIRGDKGSDDRRSYASMGAGGRANVANEEDINFESS
                     SKDRNIVFESATGKSAKGINNLTINKSINENLNFGEYGSVLGSLGQSLSDNGLKASVL
                     GNSDIIENGQLIKNRNLCLTAMDEYGRIPNGNVDTINKKDLSMPYGISTDYDKLIVET
                     KEAYKNNDVIFVELGDTYRLDLYKPNLNEKTYESMKDNIEKNIDIYLKNIFSMVEEND
                     TVYIASAFPSDLDYKNKRRLSPIIKLNGEGKGILSSSTTRREGIVTNLDVGVEILDNF
                     NIKNQNMVGRKYELINRDDNKEFLMDEYQKIVSISSIRSTILNGFVSIVFLSWIVAMI
                     AILFRKHISKNYKETTFFILKELLKIGIVMPLSFMITPIMNFKTPLAISLGIIIITLT
                     IYLISKVLIKNDLKNMLFFTGLTIVIMVIDAGFGSYLMKSNVMSYDCIIGARYYGVGN
                     EYQGVAIGSAIFTFAILLTYKNIPKWSIIVFSLVILITSASPIMGANVGSAISECVAF
                     LLFILLIYNVKIDFKKIVLLGIAVVFVLGVFVAIDMILGSNSHLGMFVKEIYFNGPGE
                     IIQTFSRKIEMNLKLAQTSAWVNILLTGIGVILVLMINQIRYFKQLMDEYPIVFKGFI
                     ASIAGCLVTLLVNDSGIVSSATAFIYVIVPMITLSINLTALKE"
     gene            complement(19026..19871)
                     /locus_tag="PC465_001717"
     CDS             complement(19026..19871)
                     /locus_tag="PC465_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2649017.1"
                     /translation="MNRNNFSHEIIEPIDNLDVNFKLFDDSGSYVANHWHNSLEIIYI
                     TSGDLQINMEGYTYNLKANECMFINSGIIHSTRCIYQNTSILLQVPLSFLNKYIPDFK
                     NCYFDFKVNANDNNYKKNSSKVKLILENMREIKLSSPPAANLLFTSLLFELLFELYTN
                     FKISVGNKNMKKTVLDLSKFEPVLEYTKINYKMPISINKIAKVAHLQPEYFCRKFKQY
                     MGQTYLEYLNDVRISHIYKDLINTNDTLCSILEAHGFTNTKLFYRIFKEKFKCTPKHI
                     RKKST"
     gene            20088..21254
                     /locus_tag="PC465_001718"
     CDS             20088..21254
                     /locus_tag="PC465_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="HDF2649018.1"
                     /translation="MYIKGVNLGGWLVLEKWMTSSLFEGTEAEDEYYLPRQLSREAYE
                     SRIKTHRSEYITERDFATIKSMGFNSVRIPVPYFIFGDCEPFIGCVKELDKAFAWADK
                     YGLSILIDLHTVPGSQNGFDNGGISGICSWSQNPEYVAFTLNVLERLAKRYGMRHELY
                     GIQILNEPITERMWNIMNVPNRFKAVDKEMARGSKPNSLEFLRDFYIKAYKVMRPYMR
                     EENVIVFHDAFELKAWKDFMREEEFKNVVLDTHQYLMLAEADGCEQSIDSYLKYIREN
                     YAKDILQMQKYFPVICGEWSLFNSYACGIDTNGGQSPLNGIESNIDKLSKDDKRELYR
                     KIAKAQLDAWRNGSGHYYWNYKLLLDTVNEEGWIGWDSWDLGKCVAQEWYPIEY"
     gene            21276..22922
                     /locus_tag="PC465_001719"
     CDS             21276..22922
                     /locus_tag="PC465_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HDF2649019.1"
                     /translation="MIKNPILPGFNPDPCICRKGDDYYLVVSSFEWFPGIPVYHSKDL
                     KNWELYTHILTDETKIDLKKLPSSKGIWAPCLTYCEEEDLFYIVYGIMNSMNARYFDV
                     DNYLITSKDIKGEWSEPVYLHSSGFDASIFHDDDGKKWIASLDWETREGYEKPGVICL
                     VEYCTKKKEIVGYPKRIWSGGTDRGCIEAPHITKRGDYYYIMCAEGGTGYGHSVTMGR
                     AKNIWGPYEKDSMNPIVTSIPGDFYERHDPDHLKPKYYNPESKLQKSGHGSYIETTSG
                     EVYLVHLTSRPFVPELRCTLGRETAIQKMKWTKDNWLRMEDESNLAKEYVSESKLEEH
                     LVSSIPSFDDFDSNELGLQYYAPRISPLSFADVKSRPGYVRIRGQESRTSLNKVSILA
                     RKLTSVYARITTKMEFYPEVHQHSAGLIMYYDNMNYINLRKYYSETLGQSALSIIHLE
                     NGEKTEFLNTRIPIKDIPIYLRLYVQGRKSYFEWSYDEKNYQRIGKVFDTTKFSDEYC
                     KYGEFTGTFIGLTCADRVKHKHYADFDFFEYIVDESKDVD"
     gene            23019..24392
                     /locus_tag="PC465_001720"
     CDS             23019..24392
                     /locus_tag="PC465_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2649020.1"
                     /translation="MNTEVNVKATTIRYEKISFFERISYGCGDLGCNIIYSAMSAFLL
                     FYYTNYADVSAAAVGSIMLVSRILDGFSDLTMGIIVDRTKSKYGKARPWILRMAIPFA
                     IAAVLLFSVPSNLGITSKLIYIFITYNLVSTVIYTAINVPYATLNSLITQNQYERGVL
                     SIFRMILATCGTLLINGLTLPLVEYFGNNLSAWTKTFFVFGIASIMVFFITFTGTKER
                     VKAVKQDRNEVIPFKIGIKSLFRNKYWIQITLCLVCIFIVFAINGGSSVYYAKFILGD
                     EKLFGPINMVSNISQIIAMFMVAPFIKKFGKRNVLIVGSIILISSNVMFIIVGQNHIG
                     VIFASAIKGIGSAGIASTMFAIVSDTIEYGEWKTGYRTEGLINSASSFGFKVGNGLGS
                     AILGAVLSIGGYVGTSATQSDLAIVSIKVCFIYLPIFITILQIIIMSFYKLDKEYSTI
                     LDELNTK"
     gene            24837..25790
                     /locus_tag="PC465_001721"
     CDS             24837..25790
                     /locus_tag="PC465_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HDF2649021.1"
                     /translation="MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKE
                     AFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVIVVDDKQDALTQKQELARAVSEY
                     LTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
                     LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNS
                     TIMASGYMNEADIEDLKKYNSIGAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKR
                     TIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD"
     gene            25828..26790
                     /locus_tag="PC465_001722"
     CDS             25828..26790
                     /locus_tag="PC465_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HDF2649022.1"
                     /translation="MSISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQ
                     EASSVAAVMALEKGDLVSLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMHI
                     ADIESGNLGANGVVGGGLTIAPGAALTQQYKKTGKIVLCSFGDGASNEGTFHEGINLS
                     SIWKLPIIFYCENNLYGMSTSIKRHMNIESIATRAASYGIEGISIDGYNPIEVYETVQ
                     KAAEKCRRGEGPVLIESRTYRWLGHSKSDANVYRTKEEIESWKAKDPIEFLKNYLIEN
                     NLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVYAD"
     gene            26815..27801
                     /locus_tag="PC465_001723"
     CDS             26815..27801
                     /locus_tag="PC465_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HDF2649023.1"
                     /translation="MSTRELTYAQAIKEAMSEEMRRDENVIFMGEDIGIYGGAFGVSV
                     GMIDEFGPERVRDTPISEAAIAGAAAGAAATGLRPIMEVMFMDFVTISMDAIVNQAAK
                     MRYMFGGKAQVPMVVRCPGGSGTGSAEQHSQSLEAWFCHVPGVKVVAPSTPADAKGLL
                     KAAIRDNNPVIFVENKLLYRKKGFVPEDDYVIEIGKADIKREGTDVTVITYGRMLQSV
                     EEAAETLSKENINVEIIDLRTLYPLDKETIVKSVCKTGRVLICHEAAKTGGLGGEISA
                     LITESESFDYLDAPVKRICGKDVPIPYNPELEKAVVPRVDEIEEAIKSLIVR"
     gene            27814..28860
                     /locus_tag="PC465_001724"
     CDS             27814..28860
                     /locus_tag="PC465_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HDF2649024.1"
                     /translation="MVANKIKATPAARSQARKDNIKLDRLIGSGENGRIHLVDVLNYL
                     KDNKANTTPLARRIAEDLNIDLETIVGTGYNGKIRKCDVEKLTGKETIVSTNTSKSSE
                     KKELKIENENSRMFNTVEGIFEKPNPMRATVAKRMSESYFSAPVFTFNIEVDATELKV
                     LRAKLIDTVKESTGVKLTMTDLIVMAVSKILPNHQALNSAWTDEGIFRYKDVNIAIAV
                     GLDEGLYVPVVKNANKKSLKEIAKESKELAEKVKTGKLMPADQEGNTFTISNVGMYGI
                     TTFTPIINMPSSAILGVGATQDKFVPVNGEAKIKPIMNLSLTSDHRVIDGTVAAKFLK
                     DLKELLENPLSMLV"
     gene            29027..30757
                     /gene="lpdA"
                     /locus_tag="PC465_001725"
     CDS             29027..30757
                     /gene="lpdA"
                     /locus_tag="PC465_001725"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDF2649025.1"
                     /translation="MSVEVIMPKAGVAMEEGTIVSWLKQEGEEVKIGEPILEITTDKV
                     NMEIESEGEGTLAVIIHKEEGEVLPVFTVIGVIAEKGENQEEVKAKYLSGNVSKEDTV
                     KENQNIEVKEEKINKKECNHDYDVVVIGGGPGGYLSALKAALLGGRVALVEENILGGT
                     CLNRGCIPTKTYIKTAEILEEIDQLSKRGVKVTVDKEQDIKKAIKYKNRVVKKLTAGV
                     GGLLKSRDVDVFNLKASVKEEHKVILSDGKVLDTENIIIATGSKVRILPIKGIESNLI
                     ITSTEALDLETVPEKLVIIGGGVIGCEFAEIFNSRGSKVTIVEMEDRVIPRMDKELSE
                     SLKYSLSKKGINVLTKKKVSEFKEEGNNILVCIEGEEPIKADLCLYAIGREANLSGIE
                     DLDIKIDKGSIVVNSKMETSIPSIYAVGDVTGGVMLAHAAFKMGEVAASNALGVNKEV
                     DLGALPSCVYTIPEVASVGITEEDARKKYNVKVGKFNFAGNGRALASGQEQGYVKVVA
                     DAKYGEILGIHMFGCGVAELINHAASFKALEIPTDEASELIFGHPCTSEALMEALADV
                     NGECLHLPKK"
     gene            31175..34123
                     /locus_tag="PC465_001726"
     CDS             31175..34123
                     /locus_tag="PC465_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2649026.1"
                     /translation="MRQRIKNLIENEDKKNPLTDEAISSRLNIRREDVTFLRNELKIE
                     DSRQRRKVVLIKAIKDILKEEKTINKNDITRRLNSIGFTVSRFTVIQYLKEIQDSGDL
                     KLDKESDDKKEEIINNRENKDIAFDKLIGSSGSLSTIIKLAKAAILYPPHGLHTIIMG
                     PTGVGKSELAECMYKFAVESSRFPKNAPFIVFNAADYSENPQLLLSQLFGHVKGAFTG
                     ADENKEGLVSKADGGILFIDEIHRLPHEGQEILFQLIDKGMVRKLGETRLTHKIDVMI
                     ISATSEPIDSHLLNTFKRRIPVTIEIPELVARPLNERFDIINNFFLIEAQRMGANIHI
                     KSDVLKALMLYDCIGNVGQLRSDIQVACARGLLNQLTNKLKEVNISISDVPGYVKQGL
                     IKIRNCRGKIENYVDGDLIIDSNLQGEIEKKNEDIYTFPDEIYKLTERRHIDLLEQGL
                     DFDVINRIIGGELESCIQKYIKQVKKVSISNNLPDISPIVGKYIVELTYEVIKIASQY
                     LSSLEPNLHLCLAVHLKAAFERLKEGKVISNAHLKEIIGNYPLEYSVAEKVAQYLKER
                     YNINLPKEEIGIIAIYFKMSSRRDMSEQKKIGVLLMAHGRVASSVCEVTNKLLGINHA
                     RYLDMPFEKKPEEMIEEATTIIKDIDEGRGVIILVDMGSLSYFGDIISGKTGINIRTI
                     SRFDTLLSIEVIRRAVLPDLTIDEIVDEVKGIEPQVKEKVSKCNNTKVDFRKPIILTL
                     CITGLGGACKIKKILEENIKSITEKVDIEPIGMIEYPSLDLEIKQISNDKNVIAIVGT
                     IDPQIANIPFFSLVDINDKAKLNQINNLIDTNQIGETNKKYELSDLIHKEDIFVDLQV
                     KSKEEVLKYMSKKLREKGYVTKNFYKKVVERDNLFPTELSDEIAIPHTDGIDVIRPAI
                     SIAILKKPIVWSKSKVKIILLLAVDQKCFNPLSTLLSFIETDEFKKIKNIKDRDFIRE
                     MILDGVNENN"
     gene            34101..34565
                     /locus_tag="PC465_001727"
     CDS             34101..34565
                     /locus_tag="PC465_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2649027.1"
                     /translation="MESMKIISSNLIFKNIEVSNNEDALKFLGQRLFDEQYVKESYIQ
                     AVVAREKKYATGLPTEIYGVAIPHTDIVHVNEPGIAIGILNKPVKFIMMGTDDTEIDV
                     KVVFMLAVKEPQEQLQLLEKLMTIFQDKNILNNIVDLSEESVSDLLNSKLKN"
     gene            34678..34980
                     /locus_tag="PC465_001728"
     CDS             34678..34980
                     /locus_tag="PC465_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2649028.1"
                     /translation="MGVTNVAKKILVACGTGVCTSTIAINKLKKALQDIGKLDMVNIT
                     QCKVVEVASKAPDYDLIICTTQVSSSIKTPVINGLPFLTGVGMDKLINDVLEELEL"
     gene            35042..36406
                     /locus_tag="PC465_001729"
     CDS             35042..36406
                     /locus_tag="PC465_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425524.1"
                     /note="with GatAB forms a phosphoenolpyruvate-dependent
                     sugar phosphotransferase transporter for galactitol;
                     subunit IIC forms the translocation channel and contains
                     the substrate binding site; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDF2649029.1"
                     /translation="MEGLYMEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGL
                     TVGVGFIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVGWPAASAIAFASTVGALI
                     IPIGLVVNIVMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFAAVANMVIV
                     LVMADLTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLQ
                     KKFGLFGEPLIMGSVIGVIIGIAAKYDIKGILQLGVTMGAVLILIPKMAALLMEGLLP
                     VSEAAQEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIAAILPGNKVL
                     PFADLAVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFK
                     MPEGATMISSICDGANPLSWVFVKVMNYKVIGGVVFGVIALGMAIYNRNRIINENKKL
                     SIEE"
     gene            36441..36914
                     /locus_tag="PC465_001730"
     CDS             36441..36914
                     /locus_tag="PC465_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649030.1"
                     /translation="MKKYKYDSKRYLLSVTIPGFFMILILIYALFNNYTNFNLNIYSL
                     LIIVCTYGIFNTFISSSNPKKIIIDSKCIHFTSFMTTHKYEIKDIEKIRIREFYNKKI
                     YLKINDGKLFKGRYWIRTNMFNNSIALYSYFIELEECLYPDSLKFRNKKFENKNI"
     gene            37086..37736
                     /locus_tag="PC465_001731"
     CDS             37086..37736
                     /locus_tag="PC465_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HDF2649031.1"
                     /translation="MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITP
                     SGMDYRNLTPSDIVIVDVDGNIIDGKWKASVDLSDHLYIYKHREDINSIIHTHSTYSS
                     CFAILNEPIECASTTLANEVGGSVPVAKFSPPTSKKMGKCVIEAIGDKRACLLANHGV
                     IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK"
     gene            37910..38842
                     /locus_tag="PC465_001732"
     CDS             37910..38842
                     /locus_tag="PC465_001732"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HDF2649032.1"
                     /translation="MYYLLNKSTNPYFNLALEEYLFLNDKYNDDIIIIWRNEESIFIG
                     KNQNPYQEVYHDVIEKGEIPILRRISGGGTVYHDLGNINMSFIQKDRQLHEIDFLEHT
                     KFMQKMLSTLGLDVSITERKDLFLNGKKISGSAQSIKRKNSLYHGTLLYDSDLNKLTK
                     YLNSNKATESNATKSVSSKVTNIKFLLEKDINYFLDYCVEYLKSNIKNIKELELDEED
                     IKSVYNIGEDKYKKIEWTYGKTPKFQVVLPFNNESKINIHVNRWKVSKFFISYDDNVI
                     NMDKLLDLNFFKEEIKESILENYPHYIDLINLIF"
     gene            39116..39829
                     /gene="ispD"
                     /locus_tag="PC465_001733"
     CDS             39116..39829
                     /gene="ispD"
                     /locus_tag="PC465_001733"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HDF2649033.1"
                     /translation="MYSVIIVAAGSGRRMNLDINKQFIKLREKEIIAHTIQVFYENIN
                     IDEIVVCIKKEEEDFFKENIINKYNFKNIKIAYGGKERQDSIYNGLKKLDKNCDIVLI
                     HDGARPFVDHRIINESIKVAKEKKAVVVGVPVSDTIKIVSDGTVQETPERNLLWAAQT
                     PQTFEYNLIIDAYEQAYKNNYYGTDDSMLVENIGQSVTMVMGSYENIKITSPEDLNIA
                     EQILNMEKRDEVNSRRRII"
     gene            39826..40311
                     /locus_tag="PC465_001734"
     CDS             39826..40311
                     /locus_tag="PC465_001734"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HDF2649034.1"
                     /translation="MRIGLGYDVHKLTEDRKLIIGGVEIPHDKGLLGHSDADVLIHAI
                     MDSILGALALGDIGKHFPDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQS
                     PKMAPYIESMRSNISKVLNTDIDNINIKATTEEGLGFTGAKQGIASQSICLLLLTSQN
                     N"
     misc_binding    40406..40614
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            40678..42393
                     /locus_tag="PC465_001735"
     CDS             40678..42393
                     /locus_tag="PC465_001735"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDF2649035.1"
                     /translation="MKMSKMFMPTLKEIPADAEITSHQLMVRSGMIKKMTSGVYNQLP
                     MGLRVFKKIEQIIREELNKKDCQEILCAALLPSELWKESGRWTAMGEEMFRLKDRTER
                     EYCLGPTHEEAFTDIIRQEITSYKQLPLNLYQIQVKYRDERRPRFGVMRTKTFTMKDA
                     YSFDVDDKGLDKSYQDMFDAYVSIFDRCGLENSPVQADSGAIGGSTSAEFMVKSEVGE
                     DEVVFCSGCDYAANVERAESCNLASQKEEMKELEEVHTPGAATIKELEEFLKTSPDKF
                     AKTLVYEADGKTVVVVVRGDREVNEIKVSNAIGSVIEFALATDDVVRKVTNAEVGFAG
                     PIGINADYVFIDKEIVEQRNIVVGANKTEYHIKNANYGRDFEGIVGDFRNVQEGDKCI
                     VCGKPLEIARGVEVGHIFKLGTKYSESMNANFIDKDGKSKPIVMGCYGIGVERTAAAI
                     IEQHNDEKGIIWPLSVAPYHVVIVPANMKNEEQISIAENIYNDLQAMGVEVLLDDRDE
                     RIGVKFNDSELIGIPMRITVGKNINEGKVEFKLRHKEDKEIIDIEEINEKVKAEFIRN
                     NVRLG"
     gene            42515..43960
                     /locus_tag="PC465_001736"
     CDS             42515..43960
                     /locus_tag="PC465_001736"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDF2649036.1"
                     /translation="MAKNEKQFVEEITKMEDDFPQWYTDVITKTDLVDYAPVKGFMVV
                     KPYGYALWEKMQEFMDKKFKETGHKNCYFPLLIPESLLNKEAEHVEGFAPEVAWVTHG
                     GNKKLEERLCVRPTSETIICTMYAKWLKSYRELPYLYNQWCSVVRWEKSTRPFLRTSE
                     FLWQEGHTLHETAEEAQEETIQQLEVYKALCEELLAMPVVAGQKSESEKFAGGERTYT
                     IEAMMHDGKALQSGTSHFLGQHFTKAFDITFADREGNLANPYHTSWGASTRLIGGLIM
                     THSDNRGLVLPPRVAPIQVVIVPIAAKKGNVMETVDKIYADLKAKGVAVEVDDRDNYT
                     TGWKFNEWEMKGVPVRVEIGPKDIENNQAMVFRRDTLEKDSMPLEGLADAICDLFDVI
                     HNDMFEKARKHREDNTSIVENMDEFRKALEEKPGFIKTMWCGDAECEAKIKEETGATI
                     RCLPFEQENLGHKCVYCGKEADSMVVMAKAY"
     gene            44398..45879
                     /locus_tag="PC465_001737"
     CDS             44398..45879
                     /locus_tag="PC465_001737"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HDF2649037.1"
                     /translation="MNVRVRFAPSPTGFVHIGSLRTALYNYLFAKKMGGEYILRVEDT
                     DQSRLVEGAIENMLNAMKWAGVNHSEGVILDDSGKVVQKGEYGPYIQSQRLDIYQEYI
                     KQLLDSGKAYYCFCTKERLDEVRDAQRAAGETAKYDGHCKNLSKEEVEANIKAGIPYV
                     IRLRLPENHTIKFTDLVRGDMEFNTNDLDDQVLMKTDGFPTYHFAVVVDDYLMKITHV
                     IRGEEWVSSTPKHVYLYEAFGWEAPVFVHLPNILNKEKKKLSKRQGDVAVEDFKKKGY
                     LPEGLVNYVALVGWSPEDNQELFTMEELEKAFSVERVSKSGGVFDTEKLNWVNQHYIK
                     DGDDAYLTDLAIPFLIEDGFITEEEATNKYDFLKSMISVLKEKLQYVKEVTEHASIFF
                     GDKIEVETEEGREFLRLEHIPTLIDALREKIEKTEVLNAEFVQAMLKEIQKEYKIKGK
                     NLFMGSRIILTGQMHGPDLPKVMEVLGKETCLNRIAYVKNNIL"
     gene            46100..46255
                     /locus_tag="PC465_001738"
     CDS             46100..46255
                     /locus_tag="PC465_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649038.1"
                     /translation="MYSNIDDVKKELKELCLEYVTILEKLKDEKMITEETFEKCSSQK
                     KIFLEEQ"
     gene            46400..47797
                     /locus_tag="PC465_001739"
     CDS             46400..47797
                     /locus_tag="PC465_001739"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HDF2649039.1"
                     /translation="MKVYNTLTRTKEEFVPLEEGKVKMYVCGPTVYNYIHIGNARPFI
                     IFDTLRRYLEYRGYDVTYVQNFTDVDDKIINRSHEEGISPEEVAAKYIKEYFVDCDGL
                     GIKRATVHPQVTDNIQQIIEFIKELEDKGYAYAVNGDVYFDTNKFEGYGKLSGQKQED
                     LEAGARIEVNDQKRHPMDFVLWKAKKEGEPGWDSPWGEGRPGWHIECSVMSKRYLGET
                     IDIHAGGQDLTFPHHENEIAQSEARSGKTFSKYWMHNGYININDEKMSKSKGNFFTVR
                     DISKLYDLEIVRFFMLSAHYRNPVNFSDEMLNQAKAGLERLYNTKEKLEFTLSNLVES
                     PLTEKEVELVKELDDFRQKFIDAMDDDVNTADAVSVIFELAKLINSNVDENSSLEFAK
                     KCLDEFNELTGVLNIVNKKKDTVLDKDIEELIQKRTDAKKNKEFQLADDIRQQLLDMG
                     IVLEDTRQGVKWKRI"
     gene            47782..48195
                     /locus_tag="PC465_001740"
     CDS             47782..48195
                     /locus_tag="PC465_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HDF2649040.1"
                     /translation="MEKDIKMEKTELVTMSPLVLAYLGDTVYETYIREYLIRQNTQRK
                     VNDLHKLAIKYVKAKAQATIIHEIEIELTEEESKIYKRGRNQKSNTSPKNADIIDYKH
                     ATGFEALVGYLYLNNEIERLQYIINKGIKIIERDM"
     gene            48301..49059
                     /locus_tag="PC465_001741"
     CDS             48301..49059
                     /locus_tag="PC465_001741"
                     /EC_number="2.1.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HDF2649041.1"
                     /translation="MKVKLISHTPEPEKVIAMAAKLCYSPVGTDEIEKDLTDESIEKF
                     LNMLLSIGHGSILEHASFTFSIEGISRACSHQIVRHRIASFSQQSQRYVKLEQFEYII
                     PPEIEKIEKAKELFIDSMKKDQENYDKLVEILFENHYNDLIKNGKNEKTAKRQAEKKA
                     IEDARYVFPNACETKMVFTINARSLFNFFEHRCCERAQWEIRNLAVEMLREVKKVAPI
                     LFKKTGPSCVNGSCPEGTMTCGDIVQVREKFKAL"
     gene            49072..49809
                     /gene="rlmB"
                     /locus_tag="PC465_001742"
     CDS             49072..49809
                     /gene="rlmB"
                     /locus_tag="PC465_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HDF2649042.1"
                     /translation="MASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDK
                     NIIIQYVDKHKLDEVSTSHSHQGVIAYASEYKYYELDELIDLAKNKDEDPFFIILDEI
                     TDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTI
                     KRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIG
                     NVTSLNASVAGGILLYEIFRQRLDKSK"
     gene            49812..50339
                     /locus_tag="PC465_001743"
     CDS             49812..50339
                     /locus_tag="PC465_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HDF2649043.1"
                     /translation="MKKNINHYLIIDGYNIINAWDNLKELAKEDLEDSREKLIDDIIE
                     FSEFMGYKTIIVFDAYNVKNSREKVEKRKHITIVYTREHQTADSYIEKFITSLSKYDD
                     VKVATNDYAEQQMILGKGATRMSARELKLELDRSKNKMKEKNIGLRKKIQRNWLEERL
                     DKETLSKLENIRRKR"
     gene            50404..51051
                     /gene="sigH"
                     /locus_tag="PC465_001744"
     CDS             50404..51051
                     /gene="sigH"
                     /locus_tag="PC465_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigH"
                     /protein_id="HDF2649044.1"
                     /translation="MLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNF
                     VKAKAKSYFLIGADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIK
                     TATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKM
                     NELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND"
     gene            51125..>51347
                     /gene="tuf"
                     /locus_tag="PC465_001745"
     CDS             51125..>51347
                     /gene="tuf"
                     /locus_tag="PC465_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDF2649045.1"
                     /translation="MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGE
                     AVDFANIDKAPEERERGITISTAHVEYETP"
BASE COUNT        20902 a         5512 c         9726 g        15207 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atataaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccacca aaaaaatgcg cggatgtggc ggaattggca gacgcactag
      241 acttaggatc tagcgccatt ggcgtggggg ttcgactccc ttcatccgca ccatttttat
      301 ttaatttaat aaacgagcgg gaatagttca gtggtagagc gcaaccttgc caaggttgaa
      361 gtcgcgagtt cgaatctcgt ttcccgctcc aaattttatg tttatgttgt aatgtgggtg
      421 catagctcag ctggatagag caacgccctt ctaaggcgtg tgtccggggt tcgaatccct
      481 gtgcgctcac cacatatata ttggggatta gccaagtcgg taaggcacat gactttgact
      541 catgtatgcg taggttcgag tcctgcatcc ccagccaaac agtatggtct attagctcag
      601 tcggtagagc acctgacttt taatcagggt gtcccgcgtt cgagtcgcgg atagatcacc
      661 aatggagagg tgtccgagtg gtttaaggag ctggtcttga aaaccagtga cttcgaaagg
      721 ggccgtgggt tcgaatccca ccctctccgc caaatgccca gatagctcag tcggtagagc
      781 aggggactga aaatccccgt gtcggtggtt cgattccgcc tctgggcacc aaaatgtggc
      841 ggtatagctt agttggctag agcgttcggt tcatacccga aaggtcatag gttcgactcc
      901 tattaccgct actgaaattt aatgtgggcc attagctcag ttggttagag cgcccggctc
      961 ataaccggta ggtctggggt tcgagtccct gatggcccac cacattaaat taacttatgg
     1021 tgggtatagc tcagttggtt agagcgccag attgtggctc tggaggtcgt gagttcgact
     1081 ctcattatcc accccaactt atatggtcta ttagctcagt cggtagagca cctgactttt
     1141 aatcagggtg tcccgcgttc gagtcgcgga tagatcacca aaaaggcggc gacatagcca
     1201 agtggtaagg cagtggactg caactccttg atccccagtt cgaatctggg tgtcgcctcc
     1261 aataaaatgc gctcatagct caactggata gagtgtctga ctacgaatca gaaggttagg
     1321 ggttcgagtc cctttgggcg caccatatga atagcgaggg attatagctc agctgggaga
     1381 gcacctgcct tacaagcagg gggtcacagg ttcgagccct gttaatccca ccagtgcaaa
     1441 cctctagtaa aactactaga ggttttattt ttgattgaaa aagtttttat atttaggagg
     1501 taaaaaattt gtatatagta ataggaaatg aaatagttga tagtgaagaa cttaaaataa
     1561 ttatagataa aaatagtgaa tttaaagttg aaaaagattt aagtaaaagc acaaaaagag
     1621 aagatgtaat agcatatcag ttaagtatag atttaaatta cctagattct cttataaatg
     1681 agcaatgtaa tttagccagt ctatctgatg aagagaaatt tgatgaatat atgactttgt
     1741 ctgatgaact tgcactggat ttagaagagt taatgccaaa atatacaata ataaatgcta
     1801 gagcatataa attagacgag gtatatggaa ttgtaaaaat aatactagct gtagcgtatg
     1861 cagatttagg gcacttaaaa ctttctgatg tagtaaagag gctatctaga caagtagatt
     1921 aggatatgaa tatgaactat attaaaaaaa tgtataaaat cttacgtaaa gatgaaaata
     1981 attatgtaaa catagaaaaa aacagtataa aatcaagtca attgtagaaa ttttcacata
     2041 aattcatctg aaattctata aaaaatgcct taattttaat gaggtaaatc gagtttacac
     2101 agtctaaaaa ttacttatat ttataaattt atcttattaa ttaaggaact ttcttaaaca
     2161 tcttcaaaaa taaagtattt tagtctataa tctttaatat tacacaaaca ataaaggaga
     2221 agaatagagt atgcttaaaa agtttaataa aatactagtg gctaatagag gcgaaatagc
     2281 tataagaata tttagagcct gttcagaatt ggggataaaa agtgttggta tatacagtaa
     2341 ggaagataag tatggattgt ttagaacaaa agcggatgaa tcatatttga taggagaagg
     2401 taaagggcca atagatgcat atttagatat ggatggaata atagacctag caaagagaaa
     2461 aaaagttgat gctatacatc caggatatgg ttttctagcg gagaatgcag aatttgctcg
     2521 taaatgtgaa gagaatggaa ttacttttat aggaccatca tctaaggtaa tgaatatgat
     2581 gggggataag attaactcta aaaaaatcgc aaaagaagtt aatgttcaaa ctataccagg
     2641 agtagaaaaa gcaataagaa gtactgaaga agcaaaggaa gttgcaaaca aaataggata
     2701 tcctgttatg ataaaagcat ctaatggcgg tggtggtaga ggtatgagaa ttgtacatcg
     2761 cgaagaagac ttagagcttg aatatgaaac tgcttgtagt gaatcaagaa aagcttttgg
     2821 agaagatatt atatttatag aaaaatatat agctgatcca aaacatatag aagttcaaat
     2881 attaggtgat aattatggaa atatagttca cttatatgaa agagattgtt cagttcaaag
     2941 aagacatcaa aaaataatag aatatgcacc agctttttca ttagaagata aagtaagaaa
     3001 agagatatgt gaagatgcag ttaagttatc aaaacatgtg ggttattcta atgcgggaac
     3061 attagaattt ttagtagatg caaatggtgg gcattatttt atagagatga acacaagagt
     3121 acaggttgaa catactgtaa cagagatggt tacaggaata gatatagttc aaagtcaaat
     3181 actaatagcc caaggttaca gcttagatag tgaagaaatt aatataaaat cacaagatga
     3241 tgtggaaata agaggttact ctatccaatg tagaataact acagaagacc ctaagaataa
     3301 attcatgcct gatacaggta aaattcaagt ttatagaact ggttcaggat ttggtataag
     3361 actagatgga ggaaatggat ttacaggggc aaacataagt cctcactatg atagtttatt
     3421 ggttaagaca atatcttggg atagaacatt ccaaggagca ataaataaaa ctataagatc
     3481 tataaaagaa cttagagtta gaggtgttaa aactaatgta ggattcctag ttaatgtttt
     3541 aaataatcct atattctcaa atggtaaatg tagtactaag tttatagatg aaaatccaga
     3601 tttatttgaa ataacagaaa gtaaagacag aggaacaaaa ttacttcaat ttataggaga
     3661 tgtaattgta aatgataatg cttgtaaaga aaaaccatta tttgatgcat tacatgaccc
     3721 aagaatggat aaggatggtt caaaatcgga aggaagtaaa atacttttcg ataagttagg
     3781 taaatctgca tatatagaaa agataaaaaa tgataagaaa ttactattaa cagatacaac
     3841 aatgagagat gcacatcaat cattattagc aacaagaata agaacatatg acttattaaa
     3901 agctgctaag ccaacagaaa aatatcaaaa ggatttattc tcacttgaaa tgtggggagg
     3961 agctacttat gatgttgcat atagattttt aaaagaatct ccttggcgta gattacaaaa
     4021 gctaagagaa gaaataccaa gcataatgtt ccaaatgttg cttagagcat caaatggagt
     4081 tggatataaa aactatccag ataatgtaat agaagaattt acaaaagaat ctgctagaca
     4141 aggtatagat gtatttagaa tatttgattc attaaactgg gttgaaaata tgaaaccatc
     4201 tattaataca gctttagaaa ctggaaaaat tgttgaagca actatgtgtt atacaggtga
     4261 tatactagat aagactaaaa ctaaatacaa tctagaatat tatattaaaa tggcacaaga
     4321 attagaaagc ttgggagcag acataatagc aataaaagat atgtcaggtc ttcttaaacc
     4381 atattcagct tacacactag ttaaagagtt aaagaaaaat gtaaaagcac caatacattt
     4441 acacactcat gatacaagtg gaaatggtgt agcaacttgt ttaatggcgt cagaagctgg
     4501 agtagacata attgatgctg cattagaatc tatggcagga cttacaagtc agccatcact
     4561 taatgctata gtagaggcac ttaagaatac agagagagat acaggaatag atttatttgg
     4621 atatgatgag ttaggaaaat attataagga tttaagaaaa gtttataata aatttgaaag
     4681 tgatttaact aattcttgtg cagaaatata taattttgaa ataccaggag gccaatatac
     4741 aaacttaaaa cctcaagctg atagtttagg attagttaat agatttgatg aagttaaaga
     4801 aaaatataaa gaagctaatg aagttgtagg agatataata aaagtaactc catcttcaaa
     4861 agttgtagga gacttagcta tctttatgac taaaaataaa ttagataaag acaatataat
     4921 agaagaaggt aaaaatttat cattcccaga ttctgttgtg gattactgta aaggtatgat
     4981 tggtcaacca gaaggtggaa taccaaaaga tttacaagag gtagttctaa aaggtgaaga
     5041 agctataaca gtaagaccag gttcattatt accagcagaa gattttgatg aaatagctaa
     5101 atatctaaat gaaaagtatg atataaatgc taatataaga aatgttataa gttatgcttt
     5161 atatccaaaa gtatatgaag attatatcaa acatctacaa cattataatg atatatctaa
     5221 acttgaaagt gatgtattct tctatggatt aaataaaaat gaagaatgtg aagtagaaat
     5281 agaagaaggt aaggtattaa caataagatt agttgaaatt ggtgaagtta aggaaaatgg
     5341 atttagaact ataggatttg agttaaatgg aatggttaga gaagtagaaa taaaagataa
     5401 gaatttctct ggaaaaatta ataatgttga aaaagctgat atgaatgacc ctcttcaaat
     5461 tggagcaagc ataccaggaa aagttataaa aataatggtt aaagaagaag atgaagtaaa
     5521 agcaaatcaa ccattaatcg ttatagaggc tatgaagatg gaaactataa tagttgctaa
     5581 gactgatgga gtaattaagt caatcaaagt aaaagaagat gatatggttg aagataaaca
     5641 attattaatg ataatgaagt aatttaatta aaataaatta aaaagcactc tgaaatgttt
     5701 aataaaaaat gttttagagt gtttttattt attttaatta aatatttgtt aaaaaaaaga
     5761 ggacaattac ctccagatgt agaaataaag ctagtaagga aaatgttatc taaaaattct
     5821 aaatatagta aatattttcc ataatatttc ttaggaaata acagcaaaga taaaatacat
     5881 aaatttaaaa ggtgggtgct tatatgaagg tttatgatag taaaatgttg agaaatgtag
     5941 cggtattagg acatagcgga tgtggaaaaa caaatctaat cgaaactata gcttacacag
     6001 caaacactaa taagatacct aaattaacag acaaggtaaa tatgacttat agcatgggat
     6061 taatacctat agagtataat gattataagt ttaacttatt ggatacccca ggatattttg
     6121 actttagcgg agacgttgtg tcatctctta gagcaagtga tgcagcaata atagtaatag
     6181 atgcaacagc gcctattcaa gttggtacag agaaatcatt agaactaact gagagtattc
     6241 ctaagataat gtttataaat aaaatagata atgaaaaggc aagatacaaa gatgcaatag
     6301 caatgttaag agaaaaatac aataataaga tagttcctat gataagtcct atatacaaag
     6361 ataaaaactt tgtaaagtta cataatgttt ttgaaaacat agatgattta gaaggtgaat
     6421 ttaaggaaca agctatgagt gttaaagaag cattaatgga acttatagca gaaactgatg
     6481 accaaatatt agataaatat tttaatggag aagaactaac tacagaagag atacaaaaag
     6541 gtattattat aggtatacaa agaggtgata ttatacctgt aatatgtggt tcaactataa
     6601 ataatatagg cacaaaggaa atattagata caatatcaag ttatttagaa cctatcttta
     6661 cagaggaaag caaaccattt aggggattag tatttaaaac tatggttgac ccatttgttg
     6721 gaaagatgtc atatataaaa attactgagg gtgcactttc taaggataaa gatgttttta
     6781 atataaataa aaatgtaaaa gaaaaaatag ctaatatata tacattgaga aatagtgaat
     6841 tagtagaaat agaaaaagct aaagctggtg atatagtagt tataactaaa gttaattctc
     6901 taaaaacagg agacactata tctgcagata aagatgcaga agctttagaa aagatagatt
     6961 ttcctaaacc acaaatatat tatgcagtaa ctcctaagaa taaaggtgat gaagaaaaag
     7021 tagcatctgt attaaataaa ctagtagaag aggaccctac attacattgg tatagaaata
     7081 cagagacaaa acaagcactt ttaggaggtc aaggagaact tcatataaaa acaattaaaa
     7141 ataaaatgaa agataagttt ggtgttgatg ttgaattgaa tgaccttaaa gttccttata
     7201 gagaaactat aaaaggaaca gctgatgtac aaggaaaaca taaaaagcaa tcaggtggtc
     7261 atggtcaata tggagacgta aaaataagat ttgaaagatg tgaatctgat tttgaattta
     7321 cagaagaaat atttggtggt tctgtaccaa aacaatatat accagcagtt gaaaaaggtt
     7381 taaaagactc tatgcaaaaa ggtatattag caggatatcc tgttacaaac ataaaagcta
     7441 cgctttatga tggttcatac catgatgtag actcttctga aatggccttt aagatggcag
     7501 caagtgcagc ctttaaaaaa ggtatggaag aagcacaccc aatactacta gaacctataa
     7561 tgaaacttaa gataactgtt ccagaagaat atatgggaga tgtcatgggt gatataaata
     7621 agagaagagg aaaaatattt ggaatggaac cagatgacaa agggaaacaa ataatatttg
     7681 cagaagctcc acaagcagag acatttaaat atgcaataga tttaagagca atgacacaag
     7741 gtagaggata ctttgaaatg gaattagaga gatatggaga ggttccatca cagtttgcag
     7801 aaaaaataat tgggttagct actgcaaagt aatgaacaaa ataaatagaa aaataattaa
     7861 tatatattat taaaaatatt tttagggttt taactaggta taggtttatg ttaggtaaac
     7921 ttatacctag tttttataca tttttgatga ataaaaaaat atataatact ttcttaaata
     7981 ttttaataaa aagaaagtat ttttttatta ttatttttac aaatgtttag taataaagat
     8041 gagaaggtat atttaaaata taaagtattt aaagttctga aatctaatca tgaagcaaaa
     8101 aattagcatt tggttatcaa taaatataat aaataaaaac tcataattaa tgaaagaata
     8161 aattcatatc taaatttcta taaaaaattt aaatttatac aatttagggc tttaaaaatt
     8221 taaataatag gtgtaaaata atagtcaaag aaagtcaaaa ataaaaaggt gtgtggtgat
     8281 attaatggca actatgacag atataattga aaaatttatt aaagatttga tggaagaaga
     8341 taatagcata caaattcaaa gaaatgaact agcaaacttg tttagttgtg caccatcaca
     8401 aataaattat gtcttaacaa caagatttac aatagataga ggatattaca ttgaaagtaa
     8461 aaaaggtggc ggaggatatg ttcaaataga aaaaatacga aaaagtaaag atgggcatat
     8521 tagagaacta ctaaatgaaa aaataggaag tcagatatcc tataaaaaag caaaagaatt
     8581 attagaaggt ttaaaagagt cggatttgat taacgaaaga gaattaaaat taatattata
     8641 tgcaatagat gataaatcat tgtgtatgcc aatatatgaa ttaaaagaga aggtaagatc
     8701 taatatttta aagaatataa taataggatt atttagtata gaggagtgat aatttatgct
     8761 atgtcaaaaa tgcaataaga ataaagcatc tgtatattat aataagatag tcaatggaga
     8821 aaaaacagag atgtatttat gtagtgagtg tgcaaaagag aatacagaaa tgaattttaa
     8881 cttagatatg cctttttcaa tgatggatat attttctaat ttaggttttc aacctaaaaa
     8941 agaacttgag gaaaagctag tttgtcctaa atgcaataca acatatagtg agtttaagaa
     9001 taatgggaga tttggatgta gtgaatgtta taatgcattt agtagtcaag taaatccaat
     9061 gcttcaaaat atacatgggc atatagaaca tacaggaaaa gcacctaaaa aatcttttta
     9121 taagataagt gtagaaaatg agattaaaga actaaaagaa gatttagata gagctataaa
     9181 aaatgaagag tatgaattag cagctcaatt tagagataaa attaaatatt taaaaggttc
     9241 tattgactaa gattggagtg atattatgaa agagaacata gtcatgaaat caagagttag
     9301 gctagctaga aatttaaata actatccatt tccaaataaa ttagataaag aatgtgccat
     9361 ggaaataata gaaaaagtaa aaaatgcgtt tattaattct aacttagaac aaaaagaaga
     9421 atttgatttc tataaaattg aagatttaga ccaatctaaa aaaatgctta tggttgaaga
     9481 acatataata agcccagatt tagcagaaaa tgataaaagt gcagttatag taaaaaaaga
     9541 taaaactata agcataatga taaatgaaga agaccatata aggatacaaa ctatatgtga
     9601 tgatttaaac ttagaatatg catatagtgt agcaaatgaa atagatgatt tgttagaatc
     9661 aagtttagaa tatgccttta acacaaagct aggttatcta acatcttgtc caactaatac
     9721 aggaacagga atgagagctt ctgtaatgat gcatttacca gcattaagtc aactaggcta
     9781 tatggatgaa ctttataaaa tttcatcaca aataggtata gcaattagag ggatatatgg
     9841 agaacgaaca gaagcattgg gaaatatata tcaaatatct aatcaactta cacttggaag
     9901 aacagagtct aatattatag aaaatgtaag tggacttaca aaagatgcaa tttcaaaaga
     9961 aataaaagct agagaaatat tgcaaaaaaa attaggtata aaactagaag ataaaatatt
    10021 tagatcgata gggacacttg aaaattcaag agtaatgagt agcgcagagg caatgagcca
    10081 tctatcaaat ataaaaatgg gaatagaaat gaactatata gataaactag atttaagggc
    10141 tatagaacaa cttatgatag gtatacaacc agcgcatcag tcaataatgt ataagagtga
    10201 tgatgttgag aatagagata taaatagagc aacatatatt agagaaactt tggaaaaatt
    10261 aagaggaggg atgaattgtg aacttcaata gatttacaca aagagctaaa aaggcaattg
    10321 atttagcgtt tgaatctgct aaaagtctag gacacaatat tgtcggaagt gaacatatac
    10381 ttttaggtct tttaagagaa gaagaaggta tagctgctaa agttctaagt aaagttggat
    10441 ttacagaagc ttatttagaa ggcaaaatag ttgatatgga aggtaaggga gaagaaatct
    10501 cagaagatat agtattaagt ccaaggagta aacaaatact tgaattatca ggaatgtttg
    10561 caaataaatt aaaaacaaat tatattggga ctgagcatat attattagca attattcaag
    10621 aaggtgaagg aatagctaat aagattttaa attatgctgg agtaaatgat aggactttag
    10681 cccaattaac aattgatatg atgggtatta gtgataaaaa tcaatacaaa gcagaaaata
    10741 gttacacggg caaccagaat caagcagaat ctaaagtact tgataagtat ggaagaaatc
    10801 ttacactata tgcaaaacag aataaaatag accctgtaat aggtagagaa aaagaaatac
    10861 aaagagtaat acaaatatta agtagaagaa ctaaaaacaa tccagtgttg ataggagacc
    10921 caggtgtagg gaaaacagcc atagctgaag gtctggctac aaatatagcc ttaggaaatg
    10981 ttccagaaac actaaaaaac aaaactttat actctttaga gatgggttca ttattggctg
    11041 gagctaagta tagaggagaa tttgaagaaa gaattaaaga agttgtagat gaagttgtta
    11101 aaaatggaaa cataatctta tttatagatg agatgcacac aataataggg gctgggtcta
    11161 ctggagaagg ctctatagat gcttcaaata tattaaagcc agccttagca agaggagaaa
    11221 tacaagttat aggtgcaact acaattgatg aatatagaaa gcatgttgaa aaagattctg
    11281 ctctagaaag aagattccaa ccagttatgg tagatgaacc aactaaagag gactcaataa
    11341 aaatattaga aggattaaga gataaatatg aagctcatca taaagttaaa ataactgatg
    11401 atgctataaa ggcagctgta gaattatcaa ctagatatat atcagacaga tatctgccag
    11461 ataaagctat agacttgatt gatgaagctg catcaaaagt aagattaaaa gaaaatacac
    11521 ctccttcaga aataaaaaaa ttagaactag aaatagaaaa tatagataaa gaaaaagaag
    11581 aagcagtaag atgtcaagac tttgagaaag cagccaaaat aagagatgaa caaggtctac
    11641 ttaaaaaaca attagaagat gttagagaaa gatggaacaa gtcatctaaa cattcagatt
    11701 tagttgatgg agaagttatt gctgaagtag tgggcttatg gacaggaata ccagttaata
    11761 aaattcttga agaagaggct gatagacttt tgagacttga ggaaatactg cacaatagag
    11821 ttataggtca agaacaagca gtaaaatcta tttcaaaggc aatcagaagg tcaagagcag
    11881 gtcttaaaga ccctaataga ccaattggtt catttttatt tttaggtcca acaggagtag
    11941 gtaaaacaga attatctaag gcattagcag aagtgcaatt tggagatgaa aatcaaataa
    12001 ttagaataga tatgtctgaa tatatggaaa aacatgctgt gtcaagaatg ataggttcac
    12061 ctccaggtta tgtaggtcat gatgaaggtg gtcaattaac tgaaaaagta agaagaaatc
    12121 catattcagt tatcttattt gatgagatag aaaaagctca tccagatgta tttaatattc
    12181 tgttacaaat tctagatgat ggtagactaa ctgattcaaa aggaagaact gtagatttta
    12241 agaatactat tgtaataatg acatcaaatg ttggagcatc tacaattggt agacaaaaaa
    12301 ctttaggatt tagtatagct aaaggagacg aagaagaaaa atctcaatat gaaaaaatga
    12361 aagaaaatat aatgggtgaa ttaaaacaaa gattcagacc agagttttta aacagaatag
    12421 atgatataat tgttttccac tcactaaatg aaaatcatat atcaaaaata gtacttttaa
    12481 tggcagcgaa actacaagag agattaaaag aaatggatat aaaattagaa atgagtgatg
    12541 aggctgttaa attaatttct aaatctggat ttgacttaga atatggagca agacctctta
    12601 aaagagcttt acaaaaagag ttggaagatg agctatctga agcaatctta aaaggtaatg
    12661 tgaaaaaggg aagtaatgta gtagcaaaag tcaaagatga aaaaatagtt tttgaaacta
    12721 aataatttaa tagagttgca ttttaaaata ttgcaaatat aagttttata atctaaacaa
    12781 aattttaagg gcaatgaatc tataataatt cattgtcctt aattatttta tttaatcttt
    12841 acatattgtc tttcagatat gctaaaatta tagtatagaa taaaaaatta aggatgataa
    12901 aagtatggca aaaataaaaa caaaatatgt atgtcaatct tgcggatatg aaacagctaa
    12961 atggcttggt aaatgtccag aatgtacaaa atggaataca tttgtagaag aaatagacca
    13021 aaaaagcacc aaaaaagagg tctttataat agataaatct tcatctaaac cagtcagtat
    13081 aaactcaata gagagtaaag aagaagagcg gtttacaaca gatataaatg aattagatag
    13141 agtgcttgga ggaggtatag ttaaaggctc tttagtgctt gttggtggtg accctggtat
    13201 aggtaaatca acacttttaa tccaagtatc tagtaatgtt gccaatttag gaaaaactgt
    13261 tttatatata actggagaag aatcagaatc tcaaataaaa atgagagcta aaagattagg
    13321 tattaactca gaaaatttat atatatttgc tgaaaataat ttaagtataa ttgaatctta
    13381 tttagaaagt gtaaatccag aattaataat tctagactca attcaaactg tcttcagtcc
    13441 agaaatatcc tcggcaccag gaactgtcag ccaaattaaa gaaggtactt caaaattcat
    13501 gaaaatttct aaaaaaatgg gaatttcaac gttcatagtt gggcatgtta caaaagaagg
    13561 ttcactagca ggaccaaaat tattagagca tatggttgat actgttctat attttgaagg
    13621 agaaagatat aatacttata gattagtaag agctgttaaa aatcgatttg gttcaactaa
    13681 tgaacttgga gtgtttgaaa tgagggattt aggattagta gaacttgata atccatctaa
    13741 aattttaatc tctgaaaaac caaaagatgt agcaggttca gtaataatat ctactgtaga
    13801 aggtacgaga ccaatgttac ttgaattgca agcattagtt tctcctacaa gttttggtat
    13861 accaaaaaga acatctacag gagtcgatta caatagagta ggtatgttat tagcagtatt
    13921 agaaaaacgt gttggtttgc aaatacaaaa tcaagatgtc tatataaaca tagttggagg
    13981 aataaagata aatgaaccct caattgattt agggatagcc atttctgtag catctagttt
    14041 tagaaatata ccgatagatg aagatatagc tgttacagga gaagtgggac ttacaggaga
    14101 agttagagca gtaagcttta tagaaaagag aatagctgag tgtaaaaaac ttggatttaa
    14161 aaagatagta gttcctagaa gtaattatga tgttgtaaaa gagaccaaag gcatagaaat
    14221 atggccagta gataacttaa gacaagctat aaatatagta cttgggagga atcaataaat
    14281 atggagaatt ttctagataa taaaaatatg ctatatgcat taaaaatgat atctcctgga
    14341 actccactta gattaggtct aaacaatgta ctaagagcta agactggtgg attaattgta
    14401 attgcaacaa acgaagatgt aatgaaaata gtagatggag gatttgctat aaatgcagaa
    14461 tattcaccat catatctata tgaattagct aaaatggatg gagctatagt tttaagtggt
    14521 gatgtaaaga aaatattatt tgctaatgca caacttatac ctgactattt tatagaaaca
    14581 tcagagacag gaacaagaca tagaacagca gaaagagtag caaaacaaac tggtgctata
    14641 gtcataggaa tttcacaaag aagaaatgtt ataacagttt atagaggaaa tgagaagtat
    14701 gtagtcgaag atatatctaa gatatttact aaggcaaatc aggctataca aactctggaa
    14761 aaatataaga cagtattgga ccaagctgta acaaatttaa atgccttaga gtttaatgat
    14821 ttggtaacta tttatgatgt tgcattagtc atgcaaaaga tggaaatggt aatgagagtt
    14881 acaagtataa ttgaaaaata tgtgatagaa ttgggtgatg aaggaacttt agtaagtatg
    14941 caattagaag aattaatggg tacaaccaga atagaccaga aattaatatt caaagattat
    15001 aataaagaaa acacagaaat aaaagaactt atgaaaaagg tcaaaaattt aaattcagaa
    15061 gaactaatag aattggtcaa tatggcaaaa ctattagggt atagtggttt ttcagaaagt
    15121 atggatatgc ctataaaaac aagaggttat aggattctta gcaaaataca tagactacca
    15181 acagcaataa tagaaaactt agtaaattat tttgaaaact ttcaacaaat tttagatgca
    15241 tctattgaag aattagatga ggttgaagga ataggtgaaa taagagcaac atatataaaa
    15301 aatggactca taaaaatgaa acaattagtc ttattagata gacacatatg atgaatttta
    15361 aatgaatttt actacttttt tcttgaatat aatatacact ttggtctata atagataagt
    15421 ataactaggg ggtgaagcat tgataaggaa agtaacaaga atattgttta ttttacttgg
    15481 atttacaata ggtataacaa cctatttaac attaatgaaa gattttgaaa tattaacatt
    15541 tggaaaagaa acatatggtt atatcgcagc tgtagtagca ggtataataa tagccatttt
    15601 aggatatctt atagaaccat gggttgtaaa taaagtaaaa gaaattgcta aaatagtgga
    15661 taaagaattg tcaaaatatc ctcagactga tatattgtta gggtctatgg gtcttatagt
    15721 aggatttgtt attgcgtatt tattaagtgg attagtaaat agaataccaa tagtaggtgg
    15781 aatactatcc ttactattat atttattcct aggatatctt ggaatgaaag ttgcgcttaa
    15841 aagtaaaaat gatttattta atattggaaa actaggaaga ttagcaaatc ctattaagga
    15901 taaagataag gataaagaaa ataaaaaaga agtaaaagcc attcctccaa aagtattgga
    15961 tacaagtgta ataattgatg gaagaatagc tgatatttgt aagactgggt ttatagaagg
    16021 aaaacttatt attcctgctt ttgttttgga ggaactaaga catattgcag attcttcaga
    16081 tgatttaaaa agagtaagag gtagaagagg tctggatata ttaaatataa ttcagaaaga
    16141 attaaatata gaagttgaaa taagtgagag agactttgat gatatagcag aagttgatag
    16201 taaattatta aagcttgctc aggttttaaa tggaaaagtt gttacaaatg attataactt
    16261 aaataaagtt gctcaattcc aaggtgttga agtattaaat ataaatgagt tagctaatgc
    16321 tataaaacca gttgctatac caggtgaaga tatggttgtt caagtggtta aagaaggaaa
    16381 agaggctcaa caaggtgttg catatctaga tgatggaact atgatagttg ttgatggagg
    16441 aagaaaatat atgaatgaga ctataaaagt actcgttact tctgttcttc aaactcctgc
    16501 aggtagaatg atatttgcaa aacctaaaaa ttaatatgtt caaagaaacc tataatttgg
    16561 gctgtttatt ttaaatagat ggtccaaatt tatttattta taacgataat gtttaatgta
    16621 ttcttaaaga tggggattta aatcagaaag cagggagaat ttatgagaaa aaagattata
    16681 tctttcttag caacatttat cataatatta acatcagcaa gtcagtatag ttttgcagat
    16741 gatatatcaa cacgtggaaa agtaatattt atagatatga atagaactag tatgagtaat
    16801 atgttaagaa taaaatcatt aagagaagaa ctagacaata gagggtatat tggcttgatg
    16861 aatataagag gcgataaagg aagtgatgat agaaggtcat atgctagtat gggtgctggt
    16921 ggtagagcta atgtggctaa tgaagaagat attaattttg aaagctcgag taaggataga
    16981 aatatagttt ttgaatcagc tacaggaaaa agtgcaaaag gtataaataa tttaactata
    17041 aataagtcta taaatgaaaa tttaaacttt ggagagtatg gttctgtatt agggtcatta
    17101 ggacaaagtt tatctgataa tggattaaaa gcatctgtat tgggtaattc agatataatt
    17161 gaaaatggtc aacttataaa aaatagaaac ttatgtctaa ctgcaatgga tgaatatgga
    17221 agaataccta atggaaatgt agatactata aataaaaaag acttatctat gccttatgga
    17281 atatcaactg attatgataa attgattgta gagactaaag aagcttacaa aaataatgat
    17341 gtgatttttg tggagcttgg agacacatat agattagatt tatataaacc aaatttaaat
    17401 gaaaaaacat atgagagtat gaaagataac atagaaaaaa atatagatat atatttaaaa
    17461 aatatatttt ctatggttga agaaaatgac actgtctaca tagcaagtgc atttccaagt
    17521 gatttagatt ataaaaataa aagaagactt tcgccaataa taaaattaaa tggagaaggg
    17581 aaaggtatat tatcatcttc aactactaga agagaaggta ttgtaacaaa tttagatgtt
    17641 ggggttgaaa tattagacaa ctttaatata aaaaatcaaa atatggttgg aagaaaatat
    17701 gaacttatta acagagatga taataaagaa tttttgatgg atgaatatca aaagatagta
    17761 tctatttcaa gcataaggtc tacaatactg aatggttttg taagtatagt tttcttgtca
    17821 tggatagttg ctatgattgc aattttattt agaaagcata tatcaaaaaa ttataaagaa
    17881 acaacatttt ttatattaaa ggaactttta aaaataggaa tagtaatgcc actgtcattt
    17941 atgataacac caataatgaa tttcaaaaca ccattagcaa tatctttagg aataattata
    18001 ataacactta ctatatatct tataagtaaa gttttaataa agaacgattt aaaaaacatg
    18061 ctgtttttta ctggattaac catagtaatt atggttattg atgctgggtt tggctcatat
    18121 ttaatgaaaa gcaatgttat gagttatgat tgtataattg gagctagata ttatggagta
    18181 ggaaatgagt atcaaggtgt ggcaatcggt agtgcaatat ttacatttgc aattttactt
    18241 acatataaaa atataccaaa gtggtctata atagtttttt ctttggttat cttaattaca
    18301 agtgcatctc caattatggg agcaaatgtt ggaagtgcta tttctgaatg tgttgcattt
    18361 ttactattta tactattgat atataatgta aagatagatt tcaaaaaaat cgtattatta
    18421 ggtatagcag tagtatttgt attaggagtt tttgtagcaa tagatatgat tttgggaagt
    18481 aattcacatt taggtatgtt tgtaaaagaa atttacttta atggaccagg agaaataata
    18541 caaacattta gtagaaagat agagatgaat ttaaagctag ctcaaaccag tgcatgggta
    18601 aatatactgt taactggaat aggtgtaatt ttagttctta tgattaatca gattagatac
    18661 tttaagcaac tgatggatga gtatccaatt gtatttaaag gatttatagc atcaatagca
    18721 ggatgtttag taactctttt agtgaatgac tctgggattg tgtcatcagc tacagccttt
    18781 atttatgtaa ttgtacctat gataacatta agtataaatc ttacagcatt aaaagaataa
    18841 gtactgtatg aataatatgt aaatattaat acattaattt aacttcttta tttacaaaat
    18901 aaagaagaaa gtttataaaa aataaattat aataaaaaag agtttatctc aaaattgatt
    18961 attctaatca aattttaaga taaacttttt ttattataaa gataaataac atataacctc
    19021 atattttagg tagatttttt tcttatatgt ttaggagtgc atttaaattt ttccttaaaa
    19081 attctgtaaa ataattttgt attagtaaat ccatgagctt ctaatatact gcataaggta
    19141 tcatttgtgt taattaaatc tttataaata tgagaaatac gcacatcatt taaatactct
    19201 aagtaagttt gtcccatata ctgtttaaat tttctacaaa aatattctgg ttgtaagtgt
    19261 gctaccttag cgattttgtt aatagaaata ggcattttgt aattaatctt tgtatattct
    19321 aaaactggtt caaattttga caaatcaagt actgtttttt tcatattttt attacctaca
    19381 gatattttaa agtttgtata taattcaaat aaaagttcaa ataataagct tgtaaagagc
    19441 agattagctg caggaggaga actaagttta atttctctca tgttttctaa tataagttta
    19501 actttacttg aatttttttt atagttattg tcattggcat taaccttaaa gtcaaaatag
    19561 caatttttaa aatcagggat atatttgttt agaaaagaca atggtacttg caataatata
    19621 gaggtatttt gataaataca tctagttgag tgaataattc cagaattaat gaacatacac
    19681 tcattagctt ttaaattata agtgtaaccc tccatgttaa tttgtaaatc accagaagtt
    19741 atataaatta tttctaatga gttatgccaa tgatttgcta cataactacc actatcatca
    19801 aatagtttga aattaacatc taaattatca ataggttcaa ttatttcatg tgaaaaatta
    19861 tttctgttca taataatatc ctccttataa ttttaaatta taaatagtaa atttataatg
    19921 ttcaatatta aaaagataat atagactaat aaattagata ataaacatac ttaagaaaac
    19981 ggataaaatc aaatataata actgtatatt aaaataactt aaaaaaatta ttttattata
    20041 agtgcaaaat atacctattt aaataagata agaggggagg attttatgtg tatataaaag
    20101 gtgtaaattt aggaggttgg ttagttttag aaaaatggat gacctcaagt ttatttgaag
    20161 gcacagaagc tgaagatgaa tactatttac caagacagct ttcaagagag gcatatgaat
    20221 ctagaattaa gactcatcgt agtgaataca tcacagagag agattttgca acgattaaat
    20281 ctatgggatt taattcagtt cgtataccag taccatactt tatttttgga gattgtgaac
    20341 cattcatagg atgtgttaaa gaacttgata aagcatttgc ttgggcagat aagtatgggc
    20401 ttagtatatt gatagactta catacagttc caggaagcca aaatggattt gataatggag
    20461 gaatatcagg tatatgtagc tggtcacaaa atccagaata tgtagcgttt acattaaatg
    20521 tattagaaag acttgcaaaa cgttatggga tgaggcatga attgtatgga atccaaattt
    20581 taaatgagcc tataacagaa agaatgtgga acataatgaa tgttccaaat cggtttaagg
    20641 ctgtagataa ggagatggca agggggagta aacctaattc attagagttt ttacgtgatt
    20701 tttatataaa agcatataag gtaatgcgtc cttatatgag agaggaaaac gttatagtat
    20761 ttcatgatgc atttgaatta aaagcatgga aagactttat gagagaggaa gaatttaaaa
    20821 atgttgttct agatacacac caatatttga tgttagctga agcagatgga tgtgaacaaa
    20881 gtattgatag ctatctcaaa tatattagag aaaattatgc taaagatatt ttacaaatgc
    20941 aaaaatattt tcctgttata tgtggggagt ggagcttatt taattcatat gcttgtggta
    21001 tagatacaaa tggaggtcaa tcacctctaa atgggattga atcaaatata gataaattat
    21061 caaaagacga taaaagagaa ttatatagga agatagcaaa agcacagctt gatgcatgga
    21121 gaaatggaag tggtcactac tattggaatt ataagttatt actagataca gttaatgaag
    21181 aaggttggat aggatgggat agttgggacc taggcaaatg tgtagctcaa gaatggtatc
    21241 ctatagaata ttaaactaaa attggaggaa aagatatgat taaaaaccct atacttccag
    21301 gttttaatcc agatccttgt atttgtagaa agggagatga ttattatctt gtagtttcat
    21361 cttttgaatg gtttccaggt atacctgttt atcactctaa agacttaaaa aattgggagt
    21421 tatatactca tattttgaca gatgaaacaa aaatagattt gaagaagctt ccttcatcta
    21481 aaggaatttg ggcaccttgt ttgacttatt gtgaagaaga agatttattt tacatagttt
    21541 atggaattat gaactctatg aatgcaagat attttgatgt tgataattat ttaattacat
    21601 caaaagatat aaagggagag tggagtgaac cagtatatct acactcatca ggttttgatg
    21661 cgtctatttt tcatgatgat gatggtaaaa agtggattgc atcattagac tgggagacta
    21721 gagaaggata tgaaaaacct ggtgttatat gtttagtgga atactgtaca aaaaagaaag
    21781 aaatagtagg atatccaaag agaatatggt cagggggaac tgatagaggt tgtattgaag
    21841 caccacatat aacaaagcgt ggagattact attatataat gtgtgcagaa ggtggaactg
    21901 gatatggtca tagtgtaact atgggaaggg ctaaaaatat atggggacct tatgaaaaag
    21961 attcaatgaa tccaattgta acttcaattc caggcgattt ttatgaaaga catgaccctg
    22021 accatctaaa gcctaaatac tataatccag aatcaaaact tcaaaaatct ggtcatggaa
    22081 gctatataga aacaacatca ggtgaagtat atttagttca tctaacatct agaccatttg
    22141 taccagagtt aaggtgtact ttaggtagag aaacagctat tcaaaaaatg aaatggacaa
    22201 aggataattg gcttcgaatg gaagatgaaa gtaatttggc aaaagaatac gtatcagaaa
    22261 gtaaactaga agaacattta gtttcatcta taccaagttt tgatgacttt gattcaaatg
    22321 aattaggttt acagtactat gctcctagga tttcaccatt atcatttgca gatgttaagt
    22381 ctagaccagg atatgtaagg attagaggac aagaatcaag aacatcatta aataaagtga
    22441 gcatattggc aagaaaatta acttcagtat atgcaagaat aaccactaag atggagtttt
    22501 acccagaggt acatcagcat agtgcgggtt tgataatgta ttatgataat atgaattata
    22561 taaatttaag aaagtattat agtgaaacat tgggtcaaag tgcactatca ataatacatc
    22621 ttgaaaatgg agagaaaacg gaatttttaa atactaggat accaataaaa gatataccaa
    22681 tatatcttcg tctgtatgta caaggtcgta agtcatattt tgaatggagt tatgatgaaa
    22741 aaaactacca gagaatagga aaggtatttg atacaactaa gttttcagat gagtactgta
    22801 aatatggaga atttacaggt acgtttatag gattaacttg tgcagatcgt gtaaagcata
    22861 aacactatgc tgattttgat ttttttgaat atatagtaga tgaatcaaaa gatgtcgatt
    22921 aataaaatca ttactaaaat tttcagagca aaggtaaatc ttatgctctg aaataagaaa
    22981 cattagaagg caaatcttac aaaaaggagt atggtattat gaatacagaa gttaatgtta
    23041 aagcaactac gattagatat gaaaagattt cattttttga aagaatttct tatggttgtg
    23101 gggatttggg gtgcaatatc atatactcag ctatgtcagc atttttgctg ttttattata
    23161 ctaattatgc agatgttagt gcagcagctg taggtagtat tatgcttgta tctaggatac
    23221 tggatgggtt tagtgactta acaatgggaa ttatagtgga tagaactaaa tccaaatacg
    23281 gtaaggctag gccttggatt ttgagaatgg cgattccttt tgctatagca gcagtattat
    23341 tattttctgt tccatcaaat cttggtatca cttctaaatt aatttatatt tttattacat
    23401 ataacttagt ttctactgtt atttatacag caatcaatgt accctatgca actctaaatt
    23461 cacttataac tcaaaaccag tatgaaagag gagtattaag tatatttaga atgatattag
    23521 ccacttgtgg taccttacta ataaatggac ttacactacc tctagttgaa tactttggaa
    23581 ataatttatc agcatggact aaaacattct ttgtatttgg aatagcatct ataatggtat
    23641 tttttataac atttactgga accaaggaaa gagtaaaagc agttaagcaa gataggaatg
    23701 aagtaatacc atttaaaata ggtattaaat ctttatttag aaataagtac tggatacaaa
    23761 taacattatg tttagtttgc atatttattg tatttgcgat aaatggtggt tcatccgtat
    23821 attatgcaaa gtttattttg ggagatgaaa aattatttgg tcctataaat atggtttcaa
    23881 atatatccca aattatagct atgtttatgg ttgctccttt tataaaaaaa tttggaaaaa
    23941 gaaatgtatt aatagtaggt tcaataatat taatatcgtc aaatgttatg tttataatag
    24001 ttggacaaaa tcatatagga gtaatatttg caagtgctat aaagggaata ggaagtgctg
    24061 gaatagcatc aacaatgttt gctattgttt cagatactat tgaatatgga gaatggaaga
    24121 ctggatatag aactgagggg cttataaata gtgcatctag ttttgggttt aaagtgggaa
    24181 atggattagg ttcagcaata ttaggtgcag tattatcaat tggtggttat gtaggaacat
    24241 cagctactca aagtgattta gctatagtat caataaaagt atgttttata tacctaccta
    24301 tatttataac aatattacaa attatcataa tgtcttttta taagcttgat aaagaatata
    24361 gtactatact tgatgaatta aatactaaat aatgaaaaag tttcttataa agtcttaagt
    24421 ttaattaagg tctattgtaa atgttcccta taaaaactat tatatattta tgattattga
    24481 agaattttta gagaagcgaa taataaaaat ataagaagac tttaaatgat gaaatggttg
    24541 gttttttaga aatgatttaa taagttattg ttatttaaag cattataagt ggacaattaa
    24601 tttttaattt atggagatga tatttaacaa ttagaagtaa tatataatat gcactaagaa
    24661 gcaatttttc aactatttat gaaggtggtg gtacaagaaa agtatcacct tttttttgtt
    24721 atacaaaaaa acagttgact ttttatatga accccttcta taatgttact gaaattaagt
    24781 aaaatgattg aacaaatgta aagataattg aaaagcttga ttttggagga aagcaaatga
    24841 aaaaaattgg agacttaaga ttaatgatga agtgttgttc actttattac gaagataatt
    24901 tgaatcaaca ggaaatagca aatcaattgg gaatatcaag accaacaata tcaagaatat
    24961 taaaagaagc ttttgaacaa ggaatagtaa aaatacagat agttgatgtt ttgaaaaatg
    25021 attaccaaaa aatagagaga agtttggaga gaaaatataa attaaaagaa gtaatagtag
    25081 tagatgataa acaggatgca ctaacacaaa aacaagaact agcaagagct gtatctgaat
    25141 atttaactag agtagtaaag gaaaatgata taataggtgt ttcaatagga acaacactaa
    25201 aagaaatacc aagatatgtg gaaaaaagta actgtaaaaa tgttacattt atacctctat
    25261 taggagggat tggagacaat gaaatagata ttcatgcaaa tcaaatagca gtaagtttag
    25321 cgagggcttt tggaggtgat tttaaattat tacatgctcc agctgttatg tctgacttgt
    25381 ctacaaaaga gaaactttgc aaagacgaaa aaattaaaga agtactagat ttaatagata
    25441 aaacaactat agcaattgtg ggtataggaa atcctatgag tttaaactca acaataatgg
    25501 cttctggata catgaatgaa gcagatatag aagatttaaa aaaatacaac tcaataggtg
    25561 caatttgttt acaagccttt gataaagaag gaaaaacttc tatacttgaa tttaatcaaa
    25621 gagtattagg agtgaaactg gaagatttaa aaaagataaa aagaacaata ggtgtcgctt
    25681 caggagatga aaaaatagag gcaataaagg catcattaaa agcgaaattt ataaatagtt
    25741 tagcaattaa tcacagttta gcacttaaat tattagaaga ttgtgactaa tagaaagata
    25801 gataaaagtt aacaggaggg aatgtatatg tcaatatcaa aagaaacatt gcttgaaatg
    25861 tataagagaa tgaatcaggc tagaaaattt gaagagaaag ttagttggtt ttttgcaaga
    25921 ggtatggttc atggaacaac tcacttatct gtaggtcaag aagcgtcaag tgtggcggct
    25981 gtaatggctt tagaaaaagg agatttagta tcattaactc atagaggaca tagtcaattt
    26041 ataggaatgg gaatagacct aaataaaatg atggctgaac ttatgggtaa agaaactgga
    26101 ttttgtaagg gaaaaggagg ctcaatgcat atagcagata ttgagtcagg taacttagga
    26161 gcaaatggag ttgtaggtgg aggtcttaca atagctccag gagctgcact tacacaacag
    26221 tataaaaaaa caggcaaaat agttttatgt agttttggtg atggagcatc aaatgaaggt
    26281 acttttcatg aaggaataaa tttatcttca atatggaaat tgccaataat attttactgt
    26341 gagaataatt tatacggtat gtcaacaagc ataaaacgtc atatgaatat agaaagtatt
    26401 gccactagag cagcttctta tggaatagaa ggaatatcaa tagatggata taacccaata
    26461 gaagtatacg aaacagtaca aaaagctgct gagaagtgta gaagaggaga aggacctgta
    26521 ttaattgaaa gtagaactta tagatggtta ggtcattcaa aatcagatgc aaatgtatat
    26581 agaacaaaag aagaaataga atcatggaaa gcaaaagacc ctattgaatt tttaaaaaat
    26641 tatcttatag aaaataatct atctaatgaa gatgaattag ataagattca agaatttgca
    26701 aagcaatcaa tagaagatgc agtagagttt gctcaaaata gcccaaatcc aaaaatagag
    26761 tctttattag aggatgtata tgcagactaa gaatggtaaa ggaggaaaat aaaaatgagt
    26821 acaagggaat taacatatgc acaagcaata aaggaagcaa tgtcagaaga aatgagaaga
    26881 gatgaaaatg taatatttat gggagaagat ataggaatat atggaggagc atttggtgta
    26941 tcagttggta tgatagatga atttggacca gaaagagtaa gggatactcc tatatcagaa
    27001 gcagctatag caggagcggc agcaggtgca gcagcaactg gtttaagacc tattatggaa
    27061 gtaatgttta tggactttgt aacaatttct atggatgcaa ttgtaaatca agcggcaaaa
    27121 atgagatata tgtttggagg aaaagcacaa gttccaatgg ttgttagatg tccaggaggt
    27181 tctggaactg gttcagcaga gcaacattca caaagtttag aagcttggtt ttgtcatgta
    27241 ccaggagtaa aagtagttgc accttctaca ccagcagatg ctaagggatt gttgaaagca
    27301 gctataagag ataataatcc agtcatattt gttgagaata aattgttata cagaaaaaaa
    27361 ggttttgtgc cagaagatga ttatgtaatt gaaattggaa aggcagatat taaaagagag
    27421 ggtactgatg ttacagtaat tacttatgga agaatgttac aaagtgttga agaagcagca
    27481 gagactctat caaaagaaaa tataaatgtt gaaattatag atttaagaac tttatatcca
    27541 ttagataaag agactatagt aaagagtgta tgtaaaactg ggagagtttt aatttgccat
    27601 gaagcagcta agactggtgg gctaggtgga gaaatatcag ccctgataac agaaagtgaa
    27661 tcatttgatt atttagatgc tccagtaaaa agaatttgtg gaaaagatgt gccaatacca
    27721 tataatccag agttagaaaa agcagttgtc ccaagagttg atgaaataga agaagcaata
    27781 aaatctttaa ttgttagata aggagggata gatatggtgg caaataaaat aaaagccaca
    27841 ccagcagcta gaagtcaggc aagaaaagac aatataaaat tagataggct gattggaagt
    27901 ggagaaaatg gaaggattca tttagtagat gtgttaaatt atttaaaaga taataaagca
    27961 aatactactc ctttagctag aagaatagca gaagatttaa atatagattt agaaactatt
    28021 gtaggtactg gatataatgg aaagataaga aagtgtgatg tggaaaaatt aactggaaaa
    28081 gaaactattg tatcaactaa tacatctaaa tctagtgaga aaaaagagct gaaaattgaa
    28141 aatgaaaatt caagaatgtt taacacagta gaaggaatat ttgaaaagcc aaatccaatg
    28201 agagctactg tagcaaaacg aatgtcagaa agttatttta gtgctcctgt atttacattc
    28261 aatatagaag tagatgctac agaattgaag gtacttagag caaagttaat cgacacagta
    28321 aaagaatcaa ctggagtaaa attaactatg acagatttaa tagtaatggc agtatctaaa
    28381 atacttccaa atcatcaagc cttaaattca gcatggacag atgagggtat atttagatat
    28441 aaagatgtaa atatagctat tgcagttggt ttagatgaag gcttatatgt tccggtagta
    28501 aaaaatgcaa acaaaaagtc tttaaaagaa atagcaaaag aaagcaaaga acttgcggaa
    28561 aaagtaaaga cagggaaact tatgccagca gaccaagaag gtaatacatt tacaataagt
    28621 aatgttggaa tgtatggtat aactacattt acacctataa taaatatgcc ttcaagtgca
    28681 atcttagggg taggtgctac acaagataag tttgttccag taaatggaga ggctaaaata
    28741 aaacctataa tgaacttatc attaacatca gaccatagag taatagatgg aacagtagct
    28801 gcaaaattct taaaagattt aaaagaattg ttagaaaatc ctttatcaat gcttgtatag
    28861 gttttgatat tttgttactg atataaatag tttgaataga ttatattatt ataattgttt
    28921 cagtaaattt aaagctttta tatattaaga attattttta acagtaacta tatgtgaata
    28981 tgatttgctt aattaaaata taagaaaata aataggagga gagcctatgt cagtagaagt
    29041 aataatgcca aaagcaggag tagccatgga agaaggtact atagtatctt ggctaaagca
    29101 agaaggcgaa gaagtaaaga ttggagaacc tatactagaa ataacaacag ataaagttaa
    29161 tatggagata gagtcagaag gagaaggtac acttgctgta atcatacata aagaggaagg
    29221 tgaagtatta ccagtattta cagtaatagg tgtaatagca gaaaaagggg aaaatcaaga
    29281 ggaagtaaaa gctaaatatt tatctggaaa tgtttcaaaa gaagatacag ttaaagagaa
    29341 tcaaaatata gaagttaaag aagaaaaaat aaacaaaaaa gagtgtaatc atgattatga
    29401 tgtagtggta ataggaggag gacctggggg atatttatca gcattaaaag cagctctttt
    29461 aggtggaaga gttgctttag ttgaagaaaa tatactagga ggtacttgct taaatagagg
    29521 ttgtatccct acaaagactt atataaaaac agcagaaata ttagaagaaa ttgaccaatt
    29581 atcaaagaga ggtgtaaaag taactgtaga taaagaacag gacattaaga aggccataaa
    29641 atataaaaat agagtagtta aaaaacttac agctggtgtt ggcggattat taaaaagtag
    29701 agatgtagat gtgtttaatc ttaaagctag tgttaaagaa gagcataaag taattttatc
    29761 agatggaaaa gttttagata cagaaaatat aataattgct acaggttcca aagtaaggat
    29821 attacctata aaaggaatag aatcaaattt aataataact agtacagaag cattagattt
    29881 ggaaacagtg ccagaaaaat tagtaataat tggtggtgga gtgattggtt gtgaatttgc
    29941 agagatattc aattcaagag gttctaaagt aactatagta gaaatggaag atagagtaat
    30001 cccaagaatg gataaagagt taagcgaatc tttaaaatat tctcttagta aaaaaggtat
    30061 aaatgtatta actaaaaaga aagtttctga atttaaagaa gaaggaaata acatattagt
    30121 gtgcattgaa ggtgaagagc caataaaagc agatttatgt ctatatgcta taggaagaga
    30181 agctaatctt tctggcatag aggacttaga tattaaaata gataaaggtt caatagttgt
    30241 aaatagtaaa atggaaacaa gtataccaag catatatgca gtaggtgatg ttactggagg
    30301 tgtaatgtta gctcatgctg cttttaaaat gggagaggta gcagcttcaa atgctctagg
    30361 tgtgaataaa gaagttgact taggtgcatt acctagttgt gtttatacaa ttccagaagt
    30421 agcatcagtt ggtattacag aagaggatgc tagaaaaaaa tataatgtaa aagttggtaa
    30481 gtttaatttt gctggaaatg gaagagcttt agcttctggt caagaacaag gatatgtaaa
    30541 agtagtagca gatgctaaat atggagaaat tttaggtata catatgtttg gatgtggtgt
    30601 agcagaactt ataaatcatg cagcatcatt taaagcgtta gagataccta ctgatgaagc
    30661 aagtgagttg atatttggtc atccatgtac ttcagaagct ttaatggaag ctttggcaga
    30721 tgtaaatgga gaatgtttac acttacctaa aaaataaatc taaacataaa ttattaattt
    30781 aagtctatta ttaatattaa tttatatcat aaaattttaa aacacttact tagccatacc
    30841 ccttattatg caaataattt atttgcataa taaggggtat tttttatgga aaaatataga
    30901 atatagaatc cttgtagttt ttgttgtaca aaaaagatag taatataaaa taacattatc
    30961 attttagaat gatttcaatt gtaattagga aaagtgattt ttttgttttt aaaaaaagta
    31021 ttatttgtaa aatataaaaa aaattttctt aatatttgaa taaaagaata gcttaattta
    31081 aatgttatta ctttataaaa aaataataag tacaaaaaaa acaatatatg gcatataagt
    31141 tgctatataa ataataagga gggaacaatt ataaatgagg caaagaataa aaaacttaat
    31201 tgaaaatgaa gataagaaaa atcctttaac agatgaagcg atttcaagta ggttaaatat
    31261 tcgaagagaa gatgttacct ttttgagaaa tgagttaaaa atagaagatt caagacaaag
    31321 aagaaaagtt gttttaatta aagctataaa agatatttta aaagaagaaa aaactataaa
    31381 taaaaatgat ataacaagaa gattaaacag cattgggttt acagtatcaa gatttacagt
    31441 catacaatac ttaaaagaga ttcaagattc tggtgaccta aaacttgata aagagagtga
    31501 tgataaaaaa gaagaaataa tcaataatag agaaaataaa gatatagcat ttgataaact
    31561 cataggtagt agtggtagct taagtacaat tataaaacta gccaaagcag caattcttta
    31621 tccacctcat ggtcttcata ctattattat ggggccaact ggtgttggaa agagtgagtt
    31681 agcagagtgt atgtataaat ttgcagtaga atcatccaga ttccctaaga atgcaccatt
    31741 tatagttttt aatgcagcag attattcaga gaatccacag cttttgctat cacagttatt
    31801 tggacacgtt aaaggtgctt ttacaggagc tgatgagaac aaagaaggat tagtatcaaa
    31861 ggcagatgga ggaatattgt ttatagatga aatacataga ttacctcatg aaggtcaaga
    31921 aatactattt caactgattg ataaaggtat ggtcagaaag ttaggagaaa caagactaac
    31981 acataaaata gatgtaatga ttatttcagc aacttctgag ccaatagatt ctcatttact
    32041 taatacattt aaaagacgta tacctgtaac aattgaaata ccagaattag ttgcaagacc
    32101 attaaatgag aggtttgaca ttataaataa tttcttctta atagaagctc aaagaatggg
    32161 agcaaacata catataaagt cagatgtatt aaaagctctt atgctttacg attgtatagg
    32221 taatgtaggt caacttagaa gtgatattca agtagcttgt gctaggggac tattaaacca
    32281 acttacaaac aaactaaaag aagtaaatat aagcatatca gatgtacctg gatatgtaaa
    32341 acaaggtctt ataaaaatca gaaattgtag aggaaaaata gaaaattatg tagatgggga
    32401 tttaattata gactcaaatc ttcaaggtga gatagaaaag aaaaatgaag atatatatac
    32461 ttttccagat gaaatataca aacttactga aagaagacat attgatttat tggaacaagg
    32521 tttagatttt gatgttataa atagaatcat tggaggagaa ttagaaagtt gcattcaaaa
    32581 atacataaaa caagttaaaa aagtttctat tagtaacaat cttccagata taagtccaat
    32641 tgttggaaaa tatatcgtag agctaactta tgaagtaatc aaaatagcat cacaatacct
    32701 aagttcacta gaaccgaatc tacatttatg tttagcagtt cacctaaaag cagcttttga
    32761 gagattaaaa gaaggaaaag taatatcaaa tgctcatttg aaagaaataa taggaaatta
    32821 tccactagaa tattctgtag cagaaaaggt agctcaatat ttaaaggaaa gatataacat
    32881 aaacttacca aaagaagaaa taggtataat agcaatatat tttaaaatga gtagtagaag
    32941 agatatgtct gaacaaaaaa agataggtgt acttcttatg gctcacggaa gagtagcatc
    33001 ttctgtatgt gaggttacaa ataaactatt aggaattaat cacgcaaggt atttagatat
    33061 gccatttgag aagaaaccgg aagaaatgat tgaagaagct actacaataa taaaagatat
    33121 tgatgaaggt agaggtgtga ttatattagt agatatgggt tcactttcat attttggaga
    33181 tattatttct ggaaagactg gaattaatat aaggacaata tctagatttg atacattgct
    33241 ttctatagag gttatacgaa gagcagtttt accagattta acaatagacg agatagttga
    33301 tgaagttaaa ggtatagagc cacaagtaaa agaaaaggtt agtaaatgta ataatacaaa
    33361 agtagatttt agaaaaccta taattttaac attatgtatt actggattag ggggagcttg
    33421 taagataaaa aaaatcctag aggaaaatat taaaagtata actgaaaagg ttgatataga
    33481 acctataggt atgattgaat atccaagtct tgatttagag ataaaacaaa taagcaatga
    33541 taaaaatgta atcgccatag ttggaacaat tgaccctcag atagcaaata tccctttttt
    33601 tagtctagta gacataaatg ataaagcaaa gttaaatcaa ataaataacc taattgatac
    33661 aaatcaaatt ggtgaaacaa ataaaaaata tgaattatca gatttaatac ataaagaaga
    33721 tatatttgtg gatttacagg ttaaatcaaa agaagaagtt ctaaaatata tgagtaaaaa
    33781 acttagagag aaaggttatg tgacaaaaaa tttctataaa aaagtagtgg aaagagataa
    33841 cttatttcca actgaattat cagatgaaat agcaatacct cacacagatg gaatagatgt
    33901 aattaggcca gctataagta tagccatctt aaagaagcct attgtgtgga gtaaaagtaa
    33961 agtaaaaata atacttttat tagctgtaga ccaaaagtgt tttaatccat taagcactct
    34021 actctcattt atagaaacag atgaatttaa gaagataaaa aacattaaag atagagattt
    34081 tattagggag atgatattag atggagtcaa tgaaaataat tagtagcaat ttaattttta
    34141 aaaatattga agtgtctaac aatgaagatg cattaaagtt tttgggacaa cgtttgtttg
    34201 acgaacagta tgtaaaagaa agctacatac aagctgttgt agcaagagaa aaaaagtatg
    34261 ctacagggtt accaacagaa atatacggag tggcaatacc acatacagat atagtacatg
    34321 taaatgagcc aggaatagca attggaatac tgaataaacc tgtaaaattt ataatgatgg
    34381 gtacagacga tactgaaatt gatgtaaaag ttgtatttat gttagcagtg aaagagccac
    34441 aagaacaatt gcaactatta gaaaaactta tgactatatt tcaagataag aatatactaa
    34501 ataatattgt tgacttaagt gaagaaagtg tgagtgattt attaaactct aaattgaaaa
    34561 attaaacatg taaagtatat taaaaatgta aaattaaaca tgcaaagtat gttaaaaaat
    34621 ataaaaagat tattaaagat ttctaactat agatatcttt aaaataaaat aatttcaatg
    34681 ggggtgacta atgtggctaa aaagatatta gttgcatgtg gaacaggagt atgtacttca
    34741 acaattgcta taaacaaatt aaagaaagca cttcaagaca ttggtaaatt ggatatggtt
    34801 aatattacac aatgtaaagt agtagaagtt gcatcaaaag cacctgatta tgatttaata
    34861 atttgtacta cacaagtatc tagtagtata aaaacaccag tgataaatgg attacctttt
    34921 ttaactggtg tcggaatgga taaattaatc aatgatgtat tagaagagtt agaattataa
    34981 ttaaaaaaat taaggaacat ggtctctaaa atcataagtt ttagagactt aaaattaaat
    35041 aatggagggt ctttatatgg agatattaaa tttcattgtt ggtctaggtg cacaagtaat
    35101 gatgccaata ataatatgta tttttggttt gatattaggt acaaaactag gaaaatcttt
    35161 aagagctggt ttaactgtgg gagttgggtt tataggtctt aacactatta tagctttgct
    35221 aacagataat ttaggtccag ctacacaaca aatggttaag aatttagggc taagtttatc
    35281 aataatagat gtaggatggc cagcagcatc agctatagct tttgcatcaa cagtaggggc
    35341 tttaattatt ccaataggtc ttgtggtaaa tatagttatg ctaattacca atactactca
    35401 aactgttgat gtagacatat gggattactg gcattttgct tttacaggag ctttagtggc
    35461 aggggctact caaagtgtaa tgtggggagt atttgcagca gtagcaaata tggtaattgt
    35521 attggtaatg gcagatttaa ctgctccagg tatagaggaa tatttaggta tgccaggtat
    35581 atctcttcct catggattta cacaggcatt tgttccaatt gctatagtag taaataaatt
    35641 attagactta ataccaggca taaataagat tgagataaat gctgatacat tgcagaaaaa
    35701 atttggatta tttggagaac ctttaataat ggggtctgta ataggtgtaa taattggtat
    35761 tgctgcgaaa tatgatataa aaggaatatt acaattaggt gtaactatgg gagctgtatt
    35821 aatattaatt ccaaagatgg cagcattatt aatggaagga ttattaccag tatcagaagc
    35881 tgcacaggaa tttattgaga agagatttaa aaacagaggc aagatttata taggcttaga
    35941 ttcagcagta ggaataggtc atcctgttac attatcagtt gcactagtgt tggttccttt
    36001 gactatactt atagcagcta tattgccagg aaataaagtt ttaccatttg cagatttagc
    36061 agtaattcca tttgcacttg tattaatcgt accaattaca aagggaaatg tgtttagaac
    36121 attaataata ggaataatta taattacttc tggattatta atcgcaacta acttagctcc
    36181 attatttacc caaatggctt taaatgctag ttttaaaatg cctgaaggag caactatgat
    36241 ttcaagtatt tgtgatggtg cgaatccatt aagttgggta tttgtaaaag ttatgaacta
    36301 taaagttatt ggaggagtag tttttggagt tatagcttta ggaatggcta tttacaatag
    36361 gaatagaata ataaatgaaa ataaaaagct atctatagaa gaataaggtt aaaacaattt
    36421 tattaaggag tgtataggtt atgaaaaaat ataaatatga ttctaaaaga tacttactca
    36481 gtgttacaat accaggattt tttatgattt taatattgat ttatgcactg tttaataact
    36541 atacaaattt taatttgaat atatatagtt tgttaataat tgtctgtact tatggtatat
    36601 tcaatacttt tatatcatca agtaatccta aaaaaattat tattgatagc aaatgtatac
    36661 attttacctc atttatgact acacataagt atgaaattaa agatatagaa aagataagaa
    36721 taagagaatt ttataataaa aaaatttatc taaaaattaa tgatggaaaa cttttcaaag
    36781 gtaggtattg gataagaaca aatatgttta ataatagtat agcattatat agctatttca
    36841 ttgagttgga agagtgctta tatccagatt cactaaaatt tagaaataaa aaatttgaga
    36901 ataagaacat ataaaaataa aaaattgaat tgaagcctag cttaatcttt tttgataaga
    36961 tataagtttg aactttatac taaattttta gaattttcaa tcaagacaat aacataatag
    37021 ctaagcaatt agaacacaac taagatgtat aaggcatgta tatgatgaat gggaggattt
    37081 aattaatgtt attagagaaa ttaagaaaag aagtattaca agcatcttta gaccttttaa
    37141 actataattt agtgacatta acaggaggaa atgtaagtgg gagagatgaa caaactggct
    37201 atatagcaat caccccaagt ggaatggatt atagaaatct tacaccaagt gatattgtta
    37261 tagtagatgt agatggaaat attatagatg gaaaatggaa agcatcagtg gatttatcag
    37321 accacttgta tatatataag catagagaag acataaatag tataattcat acacattcta
    37381 catactcaag ttgttttgct attttaaatg aacctataga atgtgcaagt acaactcttg
    37441 caaatgaagt agggggttca gtaccagttg caaaattttc gccaccaaca tctaaaaaga
    37501 tgggaaaatg tgttattgaa gcaattggtg acaaaagagc atgtctttta gcaaatcatg
    37561 gcgtaattgc agttggtcca tctgtaggac atgctcttac agccgctgta atgttagaag
    37621 attcagcaaa agtatattac ttagcaaaat caattggcac accagtgcta ctgcctgatg
    37681 aagaaattca aagagcgaga gatgtatttt ttaatgtcta tggtcaggat aaataaatta
    37741 gataaaattt taaaagtaat atgaaaatat agatattcaa tgatattaag gagatttata
    37801 atgatataat aagtttaata gttaagaagt aaaatatgaa atgtaatagt atataaattc
    37861 atttaagact aaaaagaata agataaaata aaaaggagtc tgtatttcta tgtattactt
    37921 attaaacaaa agcacaaatc cttactttaa tttggcatta gaagaatatc tatttttaaa
    37981 tgataaatat aatgatgata ttataatcat atggagaaat gaagaatcca tttttatagg
    38041 taaaaatcaa aatccatatc aggaagtata tcatgatgtt attgaaaagg gagaaattcc
    38101 tattttaaga agaatatctg gaggaggaac tgtttatcat gacttaggta atatcaatat
    38161 gtcattcata caaaaagata ggcaacttca tgagatagat tttttggagc atactaagtt
    38221 tatgcaaaag atgctttcaa ccttaggact agatgtatct ataactgaaa gaaaagattt
    38281 atttttaaat gggaaaaaaa tttcaggctc tgcacagtct ataaaaagaa aaaattctct
    38341 ttatcatgga actcttcttt acgattcaga tttaaataaa ttaactaaat atttaaattc
    38401 aaataaagca actgaatcaa atgcaactaa atctgtttca agtaaagtta caaatattaa
    38461 gtttttactc gaaaaagata taaattactt tttagattat tgtgttgaat atttaaaatc
    38521 taatataaag aatataaaag aacttgaatt ggatgaagaa gatattaaaa gtgtatacaa
    38581 tataggagaa gataaatata aaaagataga gtggacatat ggtaaaacgc cgaaatttca
    38641 agtagtgcta ccatttaata atgaaagtaa aataaatata catgttaaca gatggaaagt
    38701 atcaaaattt tttatttctt atgatgataa tgtaattaat atggacaagt tgttagattt
    38761 gaatttcttt aaagaagaaa taaaagagag tattttagaa aattatccac attacataga
    38821 tttaatcaat ttaatatttt aatataaaac ctctaatttg ataaaattgt cttatatcaa
    38881 actagaggtt tttaatattc ttgcatatta acaaccatta caaaattgta aaattaaaaa
    38941 caacactatt gaaaaatcaa tatatattgt aataaatata tgtgtttttc attagcaaat
    39001 agacattaac tatttataca actgaaaatt taatatataa ttaatcagat ggttaaaata
    39061 aaaatattaa aagttttaat aaatgatggt taaaaataaa atacgaggtg ataccatgta
    39121 tagtgttata attgttgcag cgggaagcgg aaggagaatg aacttagata taaacaaaca
    39181 gttcataaaa ttaagagaaa aagaaattat tgctcataca attcaagttt tttatgaaaa
    39241 tataaatata gatgaaatag tggtatgtat aaaaaaagaa gaagaagatt tttttaaaga
    39301 aaatataata aataagtata actttaaaaa tataaaaata gcatatggcg gaaaagaaag
    39361 acaggactca atatataatg gtttaaaaaa attagataaa aattgtgata tagtacttat
    39421 ccatgatgga gcaagaccat ttgtcgacca tagaataatc aatgaatcta taaaggtagc
    39481 taaagaaaaa aaggctgtgg ttgtaggtgt tccagtaagt gatactataa agatagtgtc
    39541 agatggaaca gtacaagaaa ctccagaaag aaatttgctg tgggcagcac aaacccctca
    39601 aacctttgaa tataatctca taatagatgc ttatgaacaa gcatataaga acaattatta
    39661 tggtactgat gattcaatgt tggtagaaaa tataggtcaa agtgtcacta tggtaatggg
    39721 ttcttatgaa aacataaaaa taactagtcc agaagattta aatatagcag aacaaatatt
    39781 aaatatggaa aaaagagatg aagttaacag tagaaggaga attatatgag aataggatta
    39841 ggatatgatg tacacaaatt aacagaggat agaaaactta taatcggtgg tgtagagata
    39901 ccacacgata aaggtttgtt gggtcattct gatgctgatg tattgataca tgcaataatg
    39961 gattctattt taggtgctct agcattagga gatataggga agcatttccc agatacagat
    40021 gaagaatata agggagcaga tagtatgaaa ttattagaac atgtgtataa tctaataaca
    40081 agtaaaggat ataaaattgg taatatagac agtactataa ttgctcaaag ccctaagatg
    40141 gctccatata ttgagagtat gagaagtaat atatcaaaag ttttaaacac agacattgat
    40201 aatataaaca taaaggcaac aacagaagaa ggtcttggtt ttacaggagc aaaacaggga
    40261 atagcttcac aaagtatttg tttattattg ttgacaagtc agaataatta atatattatt
    40321 agtaataagt ttaatggata tcaagtaata ggcctatata gaatatctat aatgtatgaa
    40381 tttaagtgaa attaatataa atataaaatt agctatgata aagaaatagt aaaatgatga
    40441 aatcttcaca gagagaaaac ggtggtgaga gttttcaaga ggaagtcttt gaacctgtct
    40501 tttagcttaa aggtataaaa atctttacgg taggaaccgt tatattccca aaagagagct
    40561 attcatatag ctaactagag tggtaccgcg gaaattaaac ctttcgtctc tatacttgta
    40621 tagagatgag aggtttttta tattttcagg aagttaatat tcaggaggaa tctattaatg
    40681 aaaatgtcaa aaatgtttat gccgacatta aaagaaatcc cagcagatgc tgagattaca
    40741 agccatcaat taatggttag gtcaggcatg ataaaaaaaa tgacttcagg tgtttataac
    40801 caattaccaa tggggttaag agtgttcaaa aaaattgaac aaataattag agaagaatta
    40861 aataaaaaag attgtcaaga aatactttgt gcagccttac ttccttctga attatggaaa
    40921 gagtctggaa ggtggactgc tatgggtgaa gaaatgttta gactaaaaga cagaacagaa
    40981 agagagtact gtcttgggcc aacacatgaa gaagcattca ctgatataat aagacaagaa
    41041 attacttcat ataaacaatt gccactgaac ttgtaccaaa tacaagtaaa atatagagac
    41101 gagagaagac caagatttgg tgttatgaga actaagactt ttacaatgaa ggatgcctat
    41161 agttttgatg tagatgataa aggtttagat aagtcatatc aagatatgtt tgatgcatat
    41221 gtaagtatat ttgatagatg tggattggag aatagccctg tacaggcaga ttcaggagct
    41281 ataggaggtt ctacatcagc cgaatttatg gttaagtcag aagttggtga agatgaagtt
    41341 gtattttgta gtggatgtga ttatgcagcc aatgtagaaa gagcagaatc ttgtaatcta
    41401 gcatcacaaa aagaagaaat gaaagaatta gaagaggttc atacaccagg agcagctaca
    41461 ataaaagagt tagaagaatt tttaaaaact tctccagata agtttgctaa aactttagta
    41521 tatgaggcag atggaaaaac agttgtagtc gttgtaagag gagatagaga agttaatgaa
    41581 atcaaagtat ctaatgccat aggttctgtt atagaatttg ctcttgctac agatgatgta
    41641 gtgagaaaag taactaatgc agaagtagga tttgcaggtc caataggtat aaatgctgac
    41701 tatgtattta tagataaaga aattgttgaa caaagaaaca tagttgttgg ggctaataaa
    41761 actgagtacc atataaaaaa tgctaactat ggaagagatt ttgaaggaat agttggagac
    41821 tttagaaatg ttcaagaagg cgacaagtgt atagtatgtg gtaagccact tgaaatagct
    41881 agaggtgttg aagtaggaca tatatttaaa ctaggaacta agtactcaga atctatgaat
    41941 gcaaacttca tagacaaaga tggaaaatca aagcctatag taatgggatg ttatggaata
    42001 ggtgttgaaa gaacagcagc agctataatt gaacaacata atgatgagaa aggtataata
    42061 tggcctttgt cagtagctcc ataccatgtt gtgatagttc cagcaaatat gaaaaatgaa
    42121 gaacaaatat caatagctga aaatatatat aatgatttgc aagctatggg tgtagaagtt
    42181 ttattagatg acagagatga aagaataggt gtcaaattca atgattcaga attaatagga
    42241 atacctatga ggattacagt aggtaaaaat attaatgaag ggaaagtaga atttaaactt
    42301 agacataaag aagataaaga gataattgac atagaagaaa taaatgaaaa agtaaaggca
    42361 gagtttatca ggaataatgt taggttagga taataactta aataagatat tgtatagata
    42421 atcaaagttg tactttatag acaccatttt atctatatat aaggatataa aatggtgttt
    42481 ttttataaaa caaataaatg aggaggtaat tgaaatggca aaaaatgaaa aacaatttgt
    42541 tgaagaaata acaaagatgg aagatgattt tccacaatgg tacacagatg taataactaa
    42601 gactgactta gttgattatg caccagtaaa aggttttatg gttgtaaagc catatggata
    42661 tgcattatgg gaaaagatgc aagaatttat ggataaaaaa tttaaagaaa ctggacataa
    42721 aaactgttat tttccattat taataccaga gagtttatta aacaaagaag cagaacacgt
    42781 tgaaggtttt gctccagaag ttgcatgggt aacacatgga ggaaataaaa aattagaaga
    42841 aagattatgt gtaagaccta cttcagagac tataatatgt acaatgtatg cgaaatggtt
    42901 aaaatcatat agagaattac catatcttta taatcaatgg tgctcagttg ttagatggga
    42961 aaaatcaact agacctttct taagaacatc tgagttttta tggcaagaag gtcatacgtt
    43021 acatgaaaca gcagaagaag cacaagaaga aacaatacaa caattagaag tatataaagc
    43081 gctatgtgaa gaattacttg caatgccagt tgtagctggt caaaaaagtg aaagtgagaa
    43141 atttgcaggt ggtgaaagaa catatactat agaagctatg atgcatgatg gtaaagcatt
    43201 acaatcaggt acaagtcact tcctaggtca acactttact aaggcttttg atattacttt
    43261 tgcagatagg gaaggaaatt tagctaatcc ataccataca tcttggggag catctacaag
    43321 acttataggt ggacttataa tgactcatag tgataacaga ggtttagtat taccaccaag
    43381 agtagctcca attcaagttg ttatagttcc tatagctgct aaaaaaggaa atgtaatgga
    43441 gactgttgat aaaatatatg ctgatttaaa agctaaggga gtagctgtag aagttgatga
    43501 tagagataac tatacaactg gatggaaatt taatgagtgg gaaatgaaag gtgttccagt
    43561 aagagttgaa attggaccaa aagatataga aaataatcaa gctatggtat ttagaagaga
    43621 tactttagaa aaggattcta tgcctttaga aggattagct gatgctatat gtgatttatt
    43681 tgatgttata cacaatgata tgtttgaaaa agcaagaaaa catagagaag acaatacatc
    43741 tatagttgaa aatatggatg agtttagaaa agctttagaa gaaaagccag gattcataaa
    43801 gactatgtgg tgtggagatg cagaatgtga agctaagatt aaggaagaaa caggagcaac
    43861 tataagatgc ttaccttttg aacaagaaaa cttaggtcac aagtgtgtgt actgtggaaa
    43921 agaagcagat agtatggtag taatggcaaa agcttactaa aatacattta aataaaaact
    43981 ggggtagaaa gtatttaata ctttatccca gttttttgtt ttttatgagt aataaaatgt
    44041 atttgtaact atgtcataag ataagtcata gatacttata ttaaaaagaa tataatagag
    44101 aactattttt aataattaca tattaatgaa agcaaaatat tttgttatat agattttcaa
    44161 taaagcaaac aataaatata aatgaatatt agtaaggagt gcttttaatt tttagaaaat
    44221 aaatgactta aaagaaagat ttatgaaatt aaaactagga ttttctgata taataaacat
    44281 gtgtattttt aaataaaaag gatattatta ttagatttga ttaaaaataa acttgcaaaa
    44341 caatgtacta gtttaatatt atagttatat tgaataaaat atcaggagga agtaaaaatg
    44401 aatgtaagag taaggtttgc accaagtcca acaggatttg tacatatagg tagtttgaga
    44461 actgctttat ataactattt atttgcaaaa aaaatgggcg gagaatatat attaagagtg
    44521 gaagatacag accaaagtag attagtagaa ggtgctatag agaatatgct taatgctatg
    44581 aaatgggctg gtgtcaacca tagtgaaggt gttatattag atgatagtgg aaaagtagta
    44641 caaaaaggag aatatggtcc atatattcaa tctcaaagat tagatatata ccaagaatat
    44701 ataaagcaac ttttagatag tggaaaagct tactactgtt tctgtacaaa agaaagactg
    44761 gatgaagtaa gagatgctca aagagcagca ggagaaacag ctaaatatga tggtcattgt
    44821 aagaatcttt ctaaagaaga agtagaagcg aatataaaag caggaatacc atatgttata
    44881 agattaagat tgccagagaa tcatacaatt aagtttacag acttagttag aggagatatg
    44941 gaatttaata ctaatgactt agatgaccaa gtattaatga aaacagatgg atttccaact
    45001 tatcattttg cagtagttgt tgatgactat ttgatgaaaa ttacacatgt tataagagga
    45061 gaagaatggg tatcatctac tccaaaacat gtttatttat atgaagcttt tggatgggaa
    45121 gcacctgtat ttgtgcattt accaaatata cttaataaag aaaagaaaaa attaagtaaa
    45181 agacaaggtg atgtagctgt tgaagacttt aagaaaaaag gatatttacc agagggatta
    45241 gtaaactatg tagcattagt tggttggtct cctgaagata atcaagaatt gtttacaatg
    45301 gaggaattag aaaaagcgtt ctctgtagaa agagtatcta aaagtggtgg agtatttgat
    45361 actgaaaaat taaattgggt taatcagcac tatataaaag atggtgatga tgcttatcta
    45421 acagacttag caataccatt tttaatagaa gatggattta taacagaaga agaagctact
    45481 aataaatatg atttcttaaa gagtatgata tcagtactta aagagaaatt acaatatgta
    45541 aaagaagtta ctgaacatgc aagtatattt tttggagata aaatagaggt agaaactgaa
    45601 gagggaagag agttcttaag attagaacat atacctactt taatagatgc tttgagagaa
    45661 aaaatagaaa aaacagaggt attaaatgct gagtttgttc aagctatgct taaagaaata
    45721 caaaaagagt acaaaataaa agggaaaaat ttatttatgg gctcaagaat aattttgaca
    45781 gggcaaatgc atggtccaga tttaccaaaa gtaatggaag ttttaggaaa agaaacttgc
    45841 ttaaatagaa tagcttatgt aaaaaataat atattatagt cataaaagtc cgctaattta
    45901 gaagcggact ttttttgtgt tagtatttgg tgaaaatatc tgcttaagaa aatgaaggta
    45961 tttaaggtaa taaatttaat atataaaaag caaagcaaaa atataaataa aatatgaata
    46021 ataaactaat aaaatattaa gcatagaaga agggaatcta ttattttagt ttgatttaat
    46081 tattaagggg gtaattacta tgtatagtaa tattgatgat gttaaaaagg aattaaagga
    46141 gctatgctta gaatatgtta caattttaga aaaattaaaa gatgaaaaaa tgattacaga
    46201 agaaactttt gaaaagtgct cttctcaaaa aaaaatattt ttagaagaac aatagaggat
    46261 ggtaatagta ttattattat gtagtttgaa agatagtacg aaaaatgata gtaatactat
    46321 tatttattgc aattttcaac tataatataa tatataatgt taagaagata atttataaaa
    46381 atacagtgag gtgatgagtg tgaaagttta taatacattg actagaacaa aagaagaatt
    46441 tgttccatta gaagaaggaa aggtaaaaat gtatgtgtgt ggtccaacag tttataacta
    46501 tatacacata ggtaatgcaa gaccatttat aatatttgat actctaagaa ggtatttaga
    46561 gtatagagga tatgatgtaa cttatgtaca aaactttaca gatgttgatg ataagattat
    46621 aaatagaagt catgaggagg gaatatctcc tgaagaagtt gcggctaagt atataaaaga
    46681 atattttgta gactgtgatg ggctaggaat aaaaagagct actgttcatc ctcaggttac
    46741 agataatata caacagatta tagagtttat aaaagagttg gaagataagg gatatgcata
    46801 tgcagtaaat ggtgatgtat attttgatac aaataagttt gaaggttatg gaaaactttc
    46861 aggtcaaaaa caagaagatt tagaggcagg ggctagaatt gaggttaatg accaaaaaag
    46921 acatcctatg gactttgttc tttggaaggc aaaaaaagaa ggtgagccag gatgggatag
    46981 cccttgggga gaaggtagac caggatggca tatagaatgt tctgttatgt ctaagagata
    47041 tttaggtgaa acaattgata tacatgcagg tgggcaagat ttaacattcc cacatcatga
    47101 aaatgaaata gctcaaagtg aagctagaag tggaaaaaca ttctcaaaat actggatgca
    47161 taatggatat ataaatataa atgatgaaaa gatgagtaaa tcaaaaggta atttctttac
    47221 agtaagagat atatcaaaat tatatgattt agagatagta agatttttca tgttatcagc
    47281 acattataga aatccagtaa actttagtga tgagatgtta aatcaagcta aagcaggtct
    47341 tgaaagacta tataatacta aagaaaaatt agaatttacg ctaagtaatt tagtagaatc
    47401 tccgttaaca gaaaaagaag tagagcttgt taaagaatta gatgacttta gacaaaaatt
    47461 catagatgct atggatgatg atgttaatac agcagacgca gtaagtgtaa tatttgaatt
    47521 agctaagtta ataaattcta atgtagatga aaattcttct ttggagtttg ctaaaaaatg
    47581 cttagatgaa tttaatgaac ttacaggagt attaaatatt gtaaataaga aaaaggatac
    47641 tgtattagat aaagacattg aagaattgat acaaaaaaga actgatgcaa agaaaaataa
    47701 agagtttcaa ttagctgatg atattagaca acaattacta gatatgggaa ttgtattaga
    47761 agacacaaga caaggtgtta agtggaaaag gatataaaaa tggaaaaaac tgaattagtt
    47821 actatgtcac cattagtttt agcatactta ggtgatacag tgtatgagac atatataaga
    47881 gaatatttaa ttagacagaa tacacaaaga aaagttaatg atttgcataa actagctata
    47941 aagtatgtaa aagctaaagc tcaggcaact ataattcatg aaattgaaat tgagttaact
    48001 gaagaagaga gtaaaattta taaaagggga agaaatcaaa agtcaaatac ttctcctaag
    48061 aatgcagata ttatagacta caaacatgca actgggtttg aggcattagt tggatatttg
    48121 tatttaaata atgaaataga gagacttcaa tatattatca ataaaggaat caaaattatt
    48181 gaaagagata tgtaaatatt aaagagtgtt gtcttaataa taagtaataa ggcaacactt
    48241 tttttataac taatgtataa taaatatata gaaattagta atgagaaagg ataaaaagtt
    48301 atgaaagtaa aattaatatc acatacacct gaaccagaaa aagtaatagc tatggcagct
    48361 aagctatgtt attcaccagt tgggacagac gaaatagaaa aagacttaac agatgaaagt
    48421 atagagaaat ttttaaatat gttattaagt ataggtcatg ggtcaatatt agaacatgct
    48481 tcatttacat tttcaataga aggtatttca agggcatgtt cacatcaaat tgttagacat
    48541 cgtatagcta gtttttcaca acaaagtcaa agatatgtta aattagaaca atttgagtac
    48601 ataattcctc cagaaataga aaaaatagaa aaggcaaaag agttatttat agactccatg
    48661 aaaaaagacc aagagaatta tgataagtta gttgaaatat tgtttgaaaa tcattataat
    48721 gacctaataa aaaacggtaa aaatgagaaa acagctaaaa gacaagctga gaagaaagca
    48781 atagaagatg ctagatacgt atttccaaat gcatgtgaaa caaaaatggt atttactata
    48841 aatgctagaa gtttgtttaa tttctttgaa catagatgct gtgaaagagc acagtgggaa
    48901 ataagaaatt tagctgtgga gatgttaaga gaggttaaaa aggttgctcc tatattattt
    48961 aaaaagactg gtccaagttg tgtaaatgga agttgtccag aaggaactat gacttgtgga
    49021 gatatagttc aagttagaga aaaatttaag gccttgtagg aggtgaataa tttggcgagt
    49081 atagaaggaa gaaatccggt aatagaagca ataaaaagcg acagagaaat agataaaata
    49141 ttaattgcaa attcagctaa agaaggttca attaagaaaa taataggaat ggctaaagat
    49201 aagaatataa ttattcagta tgttgataaa cataagctag atgaagtaag tacaagtcat
    49261 tcacatcaag gtgtaatagc ttatgcaagt gagtataagt attatgaatt agatgagcta
    49321 atagatttag caaagaataa agatgaagac ccatttttca ttatattaga tgagataaca
    49381 gacccacata atttgggttc aataataagg acagcagatg cagtaggagc acatggagtt
    49441 atcattccaa aaagaaggtc tgtacacata actcctgtag ttgccaaagc atctgctgga
    49501 gcagtagaat atatgccagt ttgcaaggta accaatatag ttaatacaat aaaaagactc
    49561 aaagaagaag ggctgtggat tgctgcagct gatatggatg gagaaacttt ttataaacaa
    49621 aatcttactg gtcctcttgg tgtagtaatt ggaagtgaag gttttggaat atctagattg
    49681 gttaaacaaa actgtgactt tatagtaaaa atgccaatga taggtaatgt tacatcttta
    49741 aatgcatctg tagcaggtgg aatactttta tatgagatat tcagacaaag actggataaa
    49801 agtaaatagg catgaaaaaa aatataaatc attacttaat aatagatggc tacaatatta
    49861 taaatgcgtg ggacaatttg aaagaactgg ctaaagagga cttagaagat tctcgagaaa
    49921 agcttattga tgacattata gaattttctg agtttatggg ttataagact ataatagttt
    49981 ttgatgctta taatgttaaa aattctcgag aaaaagttga aaaaagaaaa cacataacaa
    50041 tagtttatac aagagaacac caaacagcag atagttatat agagaaattt ataacttctt
    50101 tatcaaagta tgatgatgta aaagtagcca ctaatgacta tgcagaacag caaatgattt
    50161 taggaaaagg tgctactaga atgtctgcaa gagaattaaa gttagagtta gatcgttcca
    50221 agaataaaat gaaggaaaaa aatatcggtt tgaggaaaaa aattcagcga aattggttgg
    50281 aggaaaggtt agataaagaa acattgtcga aacttgagaa cattcgtaga aagcgttgaa
    50341 attactaggt tctttagact ataatatacc tataaatttg ttttatatat gggggagatt
    50401 tacatgttgg tagcaaaaga aaaaagttat gagttagtgg acaattgtca gcaggatgag
    50461 tataacattg tattaagagc aagtgaaggg gataaaatag cactagagta cattattact
    50521 aaatacagaa attttgtaaa ggcaaaagca aagtcatatt ttttaattgg agcagataaa
    50581 gaagatataa tacaagaagg aatgataggc ctttataagg cagttagaga ttttgatgga
    50641 agtaagacca attcatttaa atgttttgcg gagatatgta taacaagaca aataataact
    50701 gctataaaaa ctgcaacaag acaaaaacat atacctttaa attcatatgt ttctttgaat
    50761 aaaccaatat atgatgaaga gtcagacaga acacttttag atattatagc tacaagtata
    50821 gtaacagatc cagaagagct tataattagt aaagaagagt taaaaaatat agaatcaaaa
    50881 atgaacgaat tgttaagtga cttggaatta gaagtactag aattatattt aaatggaaag
    50941 tcataccagt ttatagcgga caagcttaaa agagatgtaa agtcaataga taacgcttta
    51001 caaagggtta agagaaaatt agaaaaacat cttgaaaaca gaaatgatta atagtaaaat
    51061 acttaccata agcttattgt gagcaaaatt aatttatatc gaaagataag ggaggaaatt
    51121 caaaatggct aaagctaaat acgaaagaac aaaacctcat gttaatatag ggacaatagg
    51181 acacgtagac cacggtaaaa ctacattaac agcagcaata acaaaaacat tatatgacag
    51241 atatcaatta ggagaagcag tagatttcgc aaacatagat aaagctccag aagaaagaga
    51301 aagaggaatc acaatatcaa cagcacacgt tgagtatgaa acaccaa
//
LOCUS       DAMJXI010000023        49417 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.024, whole genome shotgun sequence.
ACCESSION   DAMJXI010000023 DAMJXI010000000
VERSION     DAMJXI010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 49417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49417
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.024"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            187..522
                     /locus_tag="PC465_001746"
     CDS             187..522
                     /locus_tag="PC465_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2649046.1"
                     /translation="MYNIDDMIYNCPVEALSNILGKKWVAIIIWKIQEDKKRFGELQR
                     AIPDCSKKMLVQQLDFLIEQGIIVNQKKLVNNVVESTYFLSESGLRLLPVMEKMIMWS
                     NKNLNCDKY"
     gene            659..1936
                     /locus_tag="PC465_001747"
     CDS             659..1936
                     /locus_tag="PC465_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HDF2649047.1"
                     /translation="MQNVNLFLVFIEGIVSFFSPCILPILPIYLSILSNSSVENLKEG
                     KTSFIGSSLFKNTIFFALGISTTFFILGSSVKVLSMFFNENKDLIMFIGGIIIIIMGL
                     FYMGIIKSSILNREKRFNVKFKEMKAITAFILGFTFSFGWTPCIGPILASVLVMVSSS
                     SNHLSANLLIAVYTIGFILPFIITAMFYSKLFKTIDKIRSNMEIIKKIGGIILIVSGI
                     LMMVNGFGSISKHFNTSQNSKIESKQEENKRENSTDKEENSDGNDSQKDSNNDNNDKG
                     SNDEDRIKSIDFTLTDQYGKTHKLSDYEGKVVFLNFWATWCPPCKEEMPYIEQLYKDY
                     NKNNDDVVILGVASPNLGREGSREHVVNFLKDQGYTFPVVLDEDGALAYQYGINAFPT
                     TFIIDKEGYVTQYIPGAMDKATMASFIENQRNK"
     gene            2057..3445
                     /locus_tag="PC465_001748"
     CDS             2057..3445
                     /locus_tag="PC465_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2649048.1"
                     /translation="MKKTFDAIIIGFGKGGKTLAGDLANRGLKVALIEKSNKMYGGTC
                     VNVACIPTKSLENSANSVKTKNINSWDEVQAEYEKAIDKKETLITKLREANYNKLNSN
                     ENVTIFTGMGTFIDEKTVQVKTENEIYELVADNIFINTGSRPFIPNIKGIENKNIVYD
                     SESLMNLRTLPKKMTIIGAGFIGLEFAGIYSSFGAEVTILNSNNGILPNEDVEDSEEI
                     IKLLAKRNVKIVNNANIKEIKEVSELAIVEYEVDGKSKELTSNMILVATGRKANTEGL
                     GLENAGIELNERGFIKVSETLKTNKEHIWAIGDINGGPQFTYISLDDYRIVINQLFGD
                     KTRTTNDRKNIPNSIFISPAFSRVGLNVKQAKEKGYEVLVAKMPVEAIPRAKQIGKAD
                     GFIKIVIDKKSNKILGASMICENSSEIIHLIQLAVDLEVEYTYLRDRVYAHPTMTEAL
                     NDILSPNMIKEV"
     gene            3816..4529
                     /locus_tag="PC465_001749"
     CDS             3816..4529
                     /locus_tag="PC465_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017208807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF434 domain-containing protein"
                     /protein_id="HDF2649049.1"
                     /translation="MNKISKRGFDDSDKRWFSSKELTRLIKAKEEIEWLLNRDYKIDP
                     VVTFVGDRYQFSIRQRDALKRAVCTDEKNIIRQSKRLSLDKIKEDTVNIDGFNLIISI
                     EVALSGGTLVIGSDGNIRDLAGLRGTYKIIDKTEEALNLIGKFFNKYNAQNLKFYLDA
                     PVSNSGNLKYRILEHAKTWGIETEVELVKNADVVLEKLDRVVSSDAVIVDKCISYFNV
                     ARGIIEEYIKECNIINLNK"
     gene            4647..5516
                     /locus_tag="PC465_001750"
     CDS             4647..5516
                     /locus_tag="PC465_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF2649050.1"
                     /translation="MRGWICVKLTKLNIKKYRAPIYKYALANVNLRSAKSTNSSIITV
                     IPQGAKMEVLDEEDDWIKVMYNSQEGYVYKDLVSVSEYAWSNLNLREDKSTTSNIITV
                     IPEKSRVEVLQVDGDWSKVVYDDKIGYVFNYFLSIDGNKPNELDYKYFYTDMIKFVNE
                     NNIKSTSDYLIVTDLRNKYTYIFKKDNGGWGQLYKWQCTIGKPETPTITGIFYISGRK
                     PSFGTDEYSVKYATRIKGGYYYHSVLYDSTGSYIIDGRLGEALSHGCIRLSTENAKWI
                     YDNIPDTTTVIIH"
     gene            complement(5671..6816)
                     /locus_tag="PC465_001751"
     CDS             complement(5671..6816)
                     /locus_tag="PC465_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF2649051.1"
                     /translation="MSIYYVPPINLLGKGCLNEAKDSIKSLGTKKAFIVSDKFLVSNG
                     TVKKVTDILSQIDVDFVVYDEVKQNPTVTNVNKGLKILKSENCDFVITIGGGSPQDCG
                     KAISILATNGGDIRDYEGINKTSKKCLPIIAITTTAGTSAEVTINYVITDEDRHVKMI
                     MVDTNSLATMTVNDPELMISKPSNLTAATGMDALTHAIEAVVANGAYDVTDSTALYAI
                     KQIFKYLPRAVKNGNDIEAREQMCYACFLNGIAFSNAGLGNVHAMAHQLGGLYDLPHG
                     VCNAMLLPIVEEENAKSAPAKFRPIAEVIGMDVNNKSDKECVDFVIDKIKALSEEVGI
                     PKSLKDVGVDNPNFELLAENSMKDACAGANPVFFDKDKIIELFMKIS"
     gene            complement(7150..7926)
                     /locus_tag="PC465_001752"
     CDS             complement(7150..7926)
                     /locus_tag="PC465_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HDF2649052.1"
                     /translation="MTSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFP
                     IVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETC
                     QLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPD
                     GLKGFTEKSITDFDVLYDQLLEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSV
                     TLPLFRANDEKIELIKKLLLNAQKNIQSMMEERNEDIVIN"
     gene            8508..9482
                     /locus_tag="PC465_001753"
     CDS             8508..9482
                     /locus_tag="PC465_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HDF2649053.1"
                     /translation="MIMDFIKKIPAGMMIVPMFIAAFINTFCPDIVQIGSFTTAVFSS
                     VGSATIIGVQLVCLGTQLQFREMPKVLKRGGILLGSKFAIGALIGILIGKLFGMDGVL
                     GLTTLAVISAVTNSNGSIYLSLMTSYGDETDCATMSLLTLNDGPFFTLIALGTSGLAN
                     VPLLSLLAAIVPILVGMIIGNFDKKMKEFLEPGCNLLVPFVGFALGSSINLASILKGG
                     LSGVLLGLISVFVGGIFIVFCDKFIGKRPGYAGWAVATTAGNAIAVPAAVALVDPSWQ
                     PYVATATTQVAAAVVVTAILVPLITSWWAKKYGCPKFPKQNEDGTITA"
     gene            9580..9885
                     /locus_tag="PC465_001754"
     CDS             9580..9885
                     /locus_tag="PC465_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF2649054.1"
                     /translation="MINAVIIDEKDNVAVAIEAIAKGSEISFKLKDKTVKTITALDDI
                     TIYHKLAIKDMAKGDKVTKYGEHIGEANQEIKSGQHVHIHNVRSVREDLDKQVMTNI"
     gene            10041..11201
                     /locus_tag="PC465_001755"
     CDS             10041..11201
                     /locus_tag="PC465_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF2649055.1"
                     /translation="MKFYGYKRPDGRVGIRNHILILPTSVCASDTTRIIASQVQGAVT
                     FNNQNGCSQVHSDQQLTMDVMAGYAANPNVYGVIVVSLGCENCQNDLVVDAIKERTNK
                     PIKTLVIQEEHGTLKTIEKAVRYAREMAQEASLLRKEEFPISELILGTECGGSDPTSG
                     LAANPLIGELSDKLVDLGATSILSETTEFIGAEHILARRAVNEEVKEKILHIVHRYEN
                     SLKLVGEEVREGNPSPGNIAGGLTSLEEKSLGCIHKGGHRQISEVYDYAKQIDKKGLV
                     IMDTPGNDASSVAGMVAGGAQIVVFSTGRGTPSGNPIAPVIKITGNKITFANMEDNMD
                     FDASPVIYGPQTMEELTDDLLNMVVDVANGKQSKAESLGYTEMAIARVCNYV"
     gene            11251..12153
                     /locus_tag="PC465_001756"
     CDS             11251..12153
                     /locus_tag="PC465_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HDF2649056.1"
                     /translation="MKFVSFTEGENECKRTGVFSKDELFIIDVNSLNLSRNFKDLNEL
                     IQNVSSEDIIKLKTIINESTFYNYDVFKRERCTVHVPIEKPIHDILCVGVNYKDHLEE
                     TQTHFDDSFEEPQKTVYFTKRVTKAIGPEDEIDGHFEINNQLDYEVELGVVIGKTGVN
                     IRKEEVEDYIFGYTVINDISARKLQKEHVQWFRGKGLDTFTSLGPCILHKSAVPFPIK
                     LKVCSRVNGEERQSSNTGLFISDVSDIVSELSKGMTLEAGDIIATGTPSGVGMGFSPP
                     RYMSSGDVVECEIESIGILKNYIK"
     gene            12233..13126
                     /locus_tag="PC465_001757"
     CDS             12233..13126
                     /locus_tag="PC465_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HDF2649057.1"
                     /translation="MKAEFLTPVVTIFDEEGNLDKEGNKKVYDHLIDGGVDGLVIMGS
                     TGEFFNMSMDMQKELIDLVTSHVNKRVKVFIGTSRMCINESIELSNYAHNSGADGVMI
                     ISPYYFSLDDDSIELFYSEIAKNTEAEIYLYNYPDRTGYDLSPELTLRLARKHKNIVG
                     YKDTVTLMGHTRDLINTMKVEFPEFKVYSGYDENFIHNLMSGGAGCIGGLSNLIPEVC
                     SKWAEAYNNRDMEKVIEIQKYINKAMDFYLITNPFIPAMKKAMNIRGLQISDYMTAPF
                     VKPNEKQVCEIKKLMNELNIC"
     regulatory      13179..13360
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            13588..14718
                     /locus_tag="PC465_001758"
     CDS             13588..14718
                     /locus_tag="PC465_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2649058.1"
                     /translation="MKFKSNVLKQFFLIAMVIFMVGGLIGCSKSDKENKQASTGKKLE
                     LKYASGFSVEDLEDGIKKVTDGDNRELILIPKKIKIPEKYKNANIVRTPVDNVLIAST
                     TQACSLRTIDELDSIKAVTTEEQYWTIKEIKDLMKDGKIHYVGSNLAPDYEKIVDLNP
                     DLTIVSSGLSEADTKFIDKLKELGLNYVVDNEYKEQNPFGRMEWTSLIAAFYDKEDMA
                     TSELNKTVQKVEEVSKKIKNKAKPKVVWASVYEGSAYIAPKDSYVDNMIKMAGGINAC
                     ASIDSNEGRVSIEQLHEVAKDADIFVYSSSSDYAPNLDSIKSSAPVLADLDVVKNGNL
                     WVFAPDYYQSVDKTDELIVDLVEMFHPGTTGEKIKHYINYDK"
     gene            14790..15815
                     /locus_tag="PC465_001759"
     CDS             14790..15815
                     /locus_tag="PC465_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF2649059.1"
                     /translation="MDFINKMRIRNTTIFIVLIISMILTFLVCVAFGSVKIEFKEVID
                     VVLRGMDNTEHYKIIYNIRIPRVLATMVGGACLAVSGILLQIFFKNPIVEPYILGVSS
                     GSTLSVALMILGGYTLGFESVNSMSIFVAAFIGALIVMSIVILFANKVKNITTLLIIG
                     IMTGYVCSGITNVLQSFANSDKLKEFTMWSMGSFSGFTWEKVEILIIVGILGLLMTVF
                     IIKPLNAFLLGEEYAKSIGINIRFFRVLIVFISSILAAIVSAFAGPIGFIGLAVPQIS
                     KMIFKTSDNRVLIPVVIFLGSIVTALCDLISRVILSPVELPISTITSLLGAPIVVMLL
                     VKRKDRA"
     gene            15818..17014
                     /locus_tag="PC465_001760"
     CDS             15818..17014
                     /locus_tag="PC465_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2649060.1"
                     /translation="MLKTNNLSVGYNNKVVISNINVEVKNGEILCLLGSNGAGKTTLL
                     RSLSKLISPIKGEIYLNGVNINCISRKALSKKMALVLTNRLLGDLMTVQDIVNIGRYP
                     YTGFFGSLSKKDLIMVDEALESVDALHLKKRYFDELSDGEKQKVLVARALVQEPEIII
                     LDEPTTHLDIKHRLELINILKKLSKEKSISVILSLHEIDIALKSCDKVALIKNNKVIA
                     YGQPEDVVDEDIINSLYELDDKNFNSLLGSVEISNKSKNEVFIIGGGGKATPIYRAFT
                     KKGIGLYSGIIHENDIDYEIGRTMGIKMFTENPFEPISDESFDLAIRNLNDSKIIIDT
                     GFSVGETNKRNIDIIKEALKLDKKVYSFRNRDESKKYYDSLDSKIEHIDKVSQIINSA
                     DINNLL"
     gene            complement(17142..17867)
                     /locus_tag="PC465_001761"
     CDS             complement(17142..17867)
                     /locus_tag="PC465_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDF2649061.1"
                     /translation="MKTISKQELEKTLEKHYLWLKNNNAGEKADLKELRLENMDLRGY
                     CLSNIDFSWSDLINLNLEKADLENSIFNNSYLSDCSLKNSILKNADLSGASFRFCDLS
                     NSDIRGANLENSNLEHATLNGVISDESTRFFKLYCPETGAFIGYKKCFNFRMVQLLIP
                     SDAKRVSATSNACRCDKAKVLSITSIDGKESFKSARAYADENFIYRVGETIVAEDFNE
                     NRWKESTTGIHFFLTREEAIGYL"
     gene            18345..20444
                     /gene="nrdE"
                     /locus_tag="PC465_001762"
     CDS             18345..20444
                     /gene="nrdE"
                     /locus_tag="PC465_001762"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HDF2649062.1"
                     /translation="MNWIELNNQVIIKNEQGKYQLEKDKEALSSYIEAFIQPKLRKFN
                     NLEERLKYLIDEGYYSKEVINQYSIDVIKNIYDMIDKHKFEFQSYMSANKFYQNYALK
                     SNDGKEILETYNDKVLIVALTLGNGDKDLALNLADKIVKQEFQPATPTFLNAGRKRAG
                     EMVSCFLLSVEDSTEGISYAISSSNHLSKIGGGVALNLSKLRASGESIKDIEGAAGGV
                     VGVAKMLEQSFSYFNQMGARQGSGAVYLTVFHPDFELLMDTKKINADEKIRLATLSLG
                     AIIPDKFMELAEKNEVAYAFYPHTVYKKYGVSLDEIEMDEWYDKLVNDSDIRKKEINP
                     RQMLTKIAQMQQESGYPYVVYIDTANREHTLKDVGIIKMSNLCCEIFQYQTPSEIEGY
                     GGKNEWGQDISCNLGSLNIANVMDNKTIESTVETAIRALSFVADSTDIKPVPTVSNSN
                     SKSHSIGLGAMNLHGYLVRENILYTSDDAIDFSNVFFAMVRYYSIKASMKIAIERNQT
                     FEGFDKSEYVKGRNSKVLSKYYEQSYLPKSEKVRALFEGIYIPTKEDWTKLLDEVKEK
                     GIYNAYLMAVAPTQSISYVQNATSSIMPITEPVEVRTYGDSTTIYPMPFLTNDNMLYY
                     QSAYRMDMRKVIDLVATVQNHVDQGISTTLFVTDEKTTRDIARHYIYAYKKGLKSLYY
                     TRTKMTRDTHECLVCSV"
     gene            20457..21428
                     /gene="nrdF"
                     /locus_tag="PC465_001763"
     CDS             20457..21428
                     /gene="nrdF"
                     /locus_tag="PC465_001763"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HDF2649063.1"
                     /translation="MTFNLHKIHNAVNWNREEDGFTQAFWEQNVKQFWLPEEISVSKD
                     IKVWNELSNKEKELYKKVLGGLTLLDTKQGNNGIPSMMSLTENLQRKAVLSFMGTMEE
                     IHAKSYSSIFMTLLSNLEIDELFEWIETEPTLQRKADLVLAQYENTTNQEGLYLSMVT
                     SVFLESFLFYSGFFYPLYLSGQGKMVASGEIISLILRDESLHGKYIGLLAQEIYDSFD
                     KMDKEMLEEKMYSILYSLMENEIEYTNVIYRESGLEKEVVNFLKYNANRALENLGFEK
                     LYTVDAINPIVLNGLSTETKTHDFFSTKGNGYQKGVYEELEDEDFII"
     gene            21504..22130
                     /locus_tag="PC465_001764"
     CDS             21504..22130
                     /locus_tag="PC465_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDF2649064.1"
                     /translation="MKYEWRKRDKELYLPKKNPVIVEIPEQKFIMLKGSGDPNSKEFT
                     EAIGVLYSLAYAIKTMPKKGIVPEGYFDYTVFPLEGIWDKGEKSKGLDVLIKEDLIYT
                     IMIRQPDFVTQDLLDKATDIVKKKKPHNLLEKVRFGSINEGLCVQMLHIGSYDNEPES
                     FDIMNEFCKKNKLIRKSYTHREIYISDARKVSPESLKTVLRFEVEREV"
     gene            22525..23154
                     /locus_tag="PC465_001765"
     CDS             22525..23154
                     /locus_tag="PC465_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649065.1"
                     /translation="MNKYLLINPVAERMYGEKFHLIKANLIKKGYIIAECEPQLEYVK
                     KQYKEYTKKTKNTMLDCRCPESISLLKRNNLINDFEVPMIEPILVRTCRVLYDKYIKS
                     KDDMLVVTCPCTQLRDFASEKFKDKGNAMFYTWKEFAEQEGVKSLGKIDESPIPLGYF
                     KDTFEKVLEVSSEDEILSEIQKIRNGFEDKYDIVEMFYCKDGCNNGDGL"
     gene            23155..23937
                     /locus_tag="PC465_001766"
     CDS             23155..23937
                     /locus_tag="PC465_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2649066.1"
                     /translation="MVNKFNNKFLRLVKSVLIFFIILLLWKITNYLGIWSDYILPSPE
                     KVYSTFLNMISDGSIFINVYASMKRVLIGFAISTAIGVPLGIFFGIYSGVYEYFKSLI
                     NFLRNTPPLALIPMLILWFGIGEESKIIIIVLASFFPIFTSTLKGIKNCDSKLIEVGR
                     VFEFSKLQIIFKIIIPNAILDIAVGLKLALGYSFRAIIGAELVAASSGLGYLISDGKE
                     MSRTDVVIVGIIVIGLLGIITDYIFSIIVKKVSKGKMVEAYE"
     gene            23930..24808
                     /locus_tag="PC465_001767"
     CDS             23930..24808
                     /locus_tag="PC465_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2649067.1"
                     /translation="MNNLVCDSGYIIRNLYKSYKVDNEEHVVLSDISLNIDRNHITVI
                     LGESGCGKTTLLRAIASLEGINSGEIRFINDNKEYRPNVGFVFQESRLMPWLNVSENI
                     AFHNQRKNTILNKVLRKFKHNKRISSKIINDNFRSLETNDNLNKSNKYNRKSNIDVEK
                     YLKMMNLQKFKNSYPNELSGGMAQRVSIARALSFNPDMLLMDEPFSALDYFTRIDMQN
                     EVIRIHKSTNKGVIFVTHDIDEALKIGKKIVVFTDERKIKEFNIEDGYNRDLTSDYYI
                     KLKKDILMTMKSNKGI"
     gene            24841..25800
                     /locus_tag="PC465_001768"
     CDS             24841..25800
                     /locus_tag="PC465_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2649068.1"
                     /translation="MKLKKLLIGITILTLATASLAGCAKKNNGEKLSEINLTYVKSPL
                     NVPSIIQKQDDLFGKEFKKDNIKVNFHEITTGPEQTQALAAGEIDFLHALGGTSALIA
                     ASNGVELKILNTYSRSPKGFMILTNNNSIKSAADLVGKKVAGPKGTILHQVLISALDK
                     EGLSMDDVEFVNMGIPEASAALSDGSVDAALIAGPAALKAMKSGSKLIANGEGLVDGI
                     IVTAVSTDFAEKHPEIVERFMKVEKETLEYVNNNFDEAMEKVAKEVDLSLEETKELYA
                     WYDFSLDITDKDISSLEDTQDFLIKNKLQEKKVNIKELIYNAK"
     gene            26114..26806
                     /locus_tag="PC465_001769"
     CDS             26114..26806
                     /locus_tag="PC465_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2649069.1"
                     /translation="MSYKVYIVEDDISISTLLKDYIEKYGFEVIVEENFDDIMITFES
                     FKPHLVLLDVNLPKFDGFYWCRCIRQQSNLPIIFISARDGNVDQIRALESGADDYITK
                     PFYYDVVMAKIKSHIRRVYGEYSPKIDERIVELDGLKFYPERLELELNGENLIITKKE
                     GILIECLIKRYPKVVSRDYLLEKIWDDIEFVEENTLNVNVSRIRKRFEELGIDNAVQT
                     VRGLGYKLNKNW"
     gene            26816..27820
                     /locus_tag="PC465_001770"
     CDS             26816..27820
                     /locus_tag="PC465_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2649070.1"
                     /translation="MKLFLKDYKGYIFIYYIGIVMTIIYCNLMKFISFGESLYILLFS
                     SFILLCFLIYKYYKNREVYNLFEKGVHSLEESFLYLGSSFLGRNISVILKQQHKLYQS
                     MIQEHKKIHSEHLTFINQWIHQMKTPISVISLQLQDYEGEEVTENIRKEIDRLNKGLD
                     MAMHFARADNFQKDFIVEKAKLNEIVSSIVNEEKRLFIKSGMIPKIQVDKFTYVYTDV
                     KWMKFIIGQLITNGVKYSKDYSNYLTIKSEENNKYVILSIIDEGIGIVSKDLKRVFDP
                     FFTGENGRKFGESTGMGLYLVKKVCDDLGHKVSIKSEVGKGTEVSIYFNKDVNSLIKV
                     "
     gene            28068..28919
                     /locus_tag="PC465_001771"
     CDS             28068..28919
                     /locus_tag="PC465_001771"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDF2649071.1"
                     /translation="MSLDVIFILKSVIIAIVEGLTEFIPVSSTGHMILVGNLIDFKGQ
                     FAEMFEVVIQLGAILAVVVLYWKKIKDSVIEFFKFIFTGGKEGKIGFRFGMNVIIGCI
                     PFAIIGVLFYDNIKSLFNLQSVIIGFIVGGILLLVVETLFRKKNHSTDNIDKITPIQV
                     LKVGTLQVLSAWPGMSRSASTIMGGWIAGLNSPTAAEFSFFLAVPAMVASSGKDLFEF
                     DYSIMTPTLWIALVVGFIVAFIVSIIVMEKFVNFLKKKPMRVFAVYRIIMGVVLAVLA
                     FTNIISV"
     gene            29023..29769
                     /locus_tag="PC465_001772"
     CDS             29023..29769
                     /locus_tag="PC465_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001637630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2649072.1"
                     /translation="MKILTVNNLSKVYGKKIIFNALNDINFSIEDGEFVGIMGPSGSG
                     KTTLLNMISTIDKPTTGTMELKGKNPLLLRGEELALFRRRELGFVFQDFNLLDTLTIG
                     ENIVLPLTLDKVSVKEQDERLNEVSTILGIKDLLGKRTFEVSGGQAQRTAIARALINN
                     PSILLADEPTGNLDSKSSKVVMELFQKINKENKVTTMMVTHDPLAASYCSRILFIKDG
                     YIYNEIYKGSSREQFYQEIMDVLTLLGGDN"
     gene            29769..31685
                     /locus_tag="PC465_001773"
     CDS             29769..31685
                     /locus_tag="PC465_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2649073.1"
                     /translation="MNIKQFAINNISRNIKAYLGYLASIVISSSLLFSFIMFTSHPDL
                     DVSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISKRQVMK
                     LIFIENMIINIVSSVIGIIIGLIFAKIFLVVMSTFLELSPLKFYIPFNAILSTLIYFM
                     ILAVLTSIFTSFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAITST
                     DQYTTYLRLVPVTSLTIVATYLFFSQFSVFFMKKLKLNKRFYRKNTNMLWISNLIYKV
                     KDNARIFFLITITSAVAFTAIGTVYSFWKDVERQINLIYPNTIYYSTMTLHNDPKKPD
                     SKEKDKERMMFIENNLKKEDVDYTRTNGEFKTVFPKKSDFNVRIMKESKYLEITETIG
                     VKPISFEDNECISLLSSSLPGNNNVKENIIVGNRGLKVAKQVEECVMPAYYKNMYVVK
                     DNFYDSIESKFIVDRFTAFEVEDSSKTIEICREFENKFNNESGMQPYLFFSKELMIGT
                     GKLMYSTFIFLAIFIGLIFFVTTSSFLYNKFYMDCQVDKKKYEQLNKLGMTYNEIKKA
                     STIEIGIVFLFPYVVAVIHSIFALTALKNSFDIEVASSAVLVMGSLFLVQIVYFLIVR
                     NNYLKEIRLNLVNF"
     gene            31964..32881
                     /locus_tag="PC465_001774"
     CDS             31964..32881
                     /locus_tag="PC465_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HDF2649074.1"
                     /translation="MMILIQSRGKMKCKELSEELEVSERQIKSYKMYLEQAGIFINST
                     PGIYGGYEIDKCNSISLIKLLDSEVSILDMINSQLEYNNDIYKNEFNNIVEKIKAVLN
                     TGEKSDTYMDYFTVQAQRNCDYESEKNKCNEIIRAYTTKHKFWIEYYSLNSGNSERIV
                     HPYGLFNYKSDTYMVAFCEKRFKFIDFKLCRIKDYKVLEEKYNVDKSFSWDEYSKNSI
                     GIYKGEEINVVIKISHPFSTIIKEKVWVNNQQIIEYDDKSIMFKAKMRGYEEIKSWIL
                     SMGAYVEVVEPDRLRNDILSEIEKMKKIY"
     gene            32959..33696
                     /gene="cas6"
                     /locus_tag="PC465_001775"
     CDS             32959..33696
                     /gene="cas6"
                     /locus_tag="PC465_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HDF2649075.1"
                     /translation="MKMKIEFSTGCIPISYNSLFMSIIKEAIRKSNEDYYKNMYYYKE
                     KNNKKTKNFTFSVYIKKYSIEGDNFIIEDKVILNISTPDLELGFHIYNGLMTSKKCLY
                     KAYELTRIRIDLSREKKVTEERVLFNALSPICVKSKEGKFLEITDDRYIEELNYITNE
                     VVKNYRGNGLKRKLEFENIGLKKVVVKESLREFKKITGKEYQYINGYKGKFILKGDID
                     DLNLIYNLGIGFRRAQGFGDVDILEWR"
     gene            33702..35579
                     /gene="cas8a1"
                     /locus_tag="PC465_001776"
     CDS             33702..35579
                     /gene="cas8a1"
                     /locus_tag="PC465_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas8b1/Cst1"
                     /protein_id="HDF2649076.1"
                     /translation="MKLRVYRGDWFFNMGIVGFLNIIKKADKQAEIFIMEDYIEFDSL
                     FLENFHEYYFNYFMDEYDVSKRIKKNIDYSINFIKSKPDRIKDGIKKIKDSVKQQNDK
                     IKKFDEEKFNLIKEKLDSMSKIKSYDEFDSLESLVDETIDIFKIKSINDRLTANLYKY
                     VVQDNYFGQVSFFNVAKAKLDLDGLKQVMFNDYLRQIIYFGELEDLLEENDYDKLKNY
                     LNDRLNSIAKDINEKKVSKSSINTIEKIMKEINKNFIKKNKSIEDIKEYMDSLEVCEM
                     CGLYKGILDEYSESNFAPLGVSTNNARNMFWNQEYVSSICDVCKLILFCTPAGATYTR
                     KNYLINEENEFYLFVNMDTSINELFERNNSLKAQKSESSDSKDENPFNQLIKSIVEEN
                     TLKSEWQLRNILFVEFKASIDSKKCKINYFNIPTYLAKFFTDKYANKKIQSIYDYKLK
                     SNVLDLLLKNRDLKHLTNNILRNKVKNDMESNNKSNISGIDCFRVVQLRVLINSYKKG
                     VYKMDSKNLEKNDEKLKIIYYLGCDIHDYFVNKNSKNKIDGVSYKLLNSVKVGNKSDF
                     MDTIIRVFMSAEKQIPAFILDIEIEKDLDFESIGHAFISGLISGKYEGKDKLPNEKEE
                     K"
     gene            35581..36495
                     /gene="cas7i"
                     /locus_tag="PC465_001777"
     CDS             35581..36495
                     /gene="cas7i"
                     /locus_tag="PC465_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HDF2649077.1"
                     /translation="MKRGLTFTVIAQAQSLNYGEGIGNISELKKLSRADGNMYTFASR
                     QCLRYDIVRLAAELFNWNLQVVDKEKGTIQFKDNISIRESEEMDLFGYMKTNKKDEKD
                     KKGGSLTREATVRLSNAISLEPYRSDMDFLNNKGFADRIGEHPNLANIEQHLSYYTYT
                     VTIDLSKIGKDGDIELDNKEKCRRVVEFLEIIKVLNRNIRGRQENLSPLFVVGGVYEI
                     ANPFFLGRIKLKGDKNGFKINKQAIEEVIQGTFLGKDLKEFTYVGMVDGVFINKEEFK
                     GLFEDNFLSVDKFFGQLVKEVKEYYGVN"
     gene            36497..37198
                     /gene="cas5b"
                     /locus_tag="PC465_001778"
     CDS             36497..37198
                     /gene="cas5b"
                     /locus_tag="PC465_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5"
                     /protein_id="HDF2649078.1"
                     /translation="MKVLKLDLFQETACYKKPFAMKITETYPLPPYSTINGLIHKVLN
                     ATEYIPFNISVQGTYESIFNNYQTTYFYKKDSITSMPMNSHMLLNVNLIIHIGGDFDL
                     LEEIYDSLLNYDEHLSLGRKEDLVRINDIRFVEVNKFEVDEDIQLDDYENYKLSECNI
                     RMPIYIPKTSLQDTDIDGISYRLNNYYDNNAVEDKKRVWNKVDSYYVEDGNTISIGDI
                     LLDNEGDLLYFNNIN"
     gene            37209..39530
                     /locus_tag="PC465_001779"
     CDS             37209..39530
                     /locus_tag="PC465_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HDF2649079.1"
                     /translation="MLYAKSNPVETLREHTDELLKQMNVLRESYGKNINSLDFLEEEI
                     FWQLLDFVIEFHDIGKAFSPFQELIKSRMDTKINEPKIVTHLENNVGHNYLSPAFIDY
                     SYIDRKKNKELRAVLNQVIVYHHERDIFIDKDFKNLIQKILDEDLINKVYELQHEFKV
                     RYPIKTERLSKVYLQSVEKRIDKNHKYYNLYIMLKGILHRLDHSASAHEVVECNNVIN
                     IGEQTENYLMKEFGSLREAQSFAKSNRNKNIILIASTGMGKTETALIWIDKDKAFFTL
                     PLRVSINALFDRAKNIVGVGESNDTFLGLLHSTAIDYLEESNQENSSEIVDLAKLLSC
                     KLTFSTIDQIFKFPFLYRGYEKVYSTLAYSKVVIDEIQAYSPEIAAVLVKGIEMIHKI
                     GGRFMIMTATMPTIYIDELKKRGVMNSNLADLTCNTEKIRHCVSIVENSIDENLGKII
                     QSGMNKKVLVIVNTVKSAVEKYELIEEIVKPKGIDVNLNLLHSMYIQEDRAKLEKYIK
                     EFADSDSNGIWITTQLVEASLDIDFDELHTENSTLDSLFQRFGRCYRSREYEENSPNI
                     FIYTEKATGIGSIYDKDIVEKGLELLKTFINGKECVKMKEKYKVEMVKILYSKESLEG
                     TAFEKRFTSALNILDTITPYSLGSKDAQNILRNIEGYTVIPEDIYNKIEETLIKDYEE
                     LGQELINAYSNDDRQLINKIKSKRKKARREIIKKTVNLPIYKAKQNVIDIQVKGLEDL
                     KILLYKYDIHENKHTKQIFGKGVLISNEIDQFI"
     gene            39545..40096
                     /gene="cas4"
                     /locus_tag="PC465_001780"
                     /pseudo
     CDS             39545..40096
                     /gene="cas4"
                     /locus_tag="PC465_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816355.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
     gene            40099..41079
                     /gene="cas1b"
                     /locus_tag="PC465_001781"
     CDS             40099..41079
                     /gene="cas1b"
                     /locus_tag="PC465_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated endonuclease Cas1"
                     /protein_id="HDF2649080.1"
                     /translation="MYKDYYIISNGDIKRKENTIYYYNLEGEKKILPVEQVDDIHIYG
                     EVDLNTKLINYISKYGVMLHFYNYYGYYSGTYYPRKKNVSGFSLVCQSACYLDKNERL
                     YLAKSFVESASYHILRNMRYYKVDESLIDTIKDELNDLNDVKEISELMGKEGRIRKTY
                     YKSFNQILKDDFEFYKREKRPPKDPVNALMSFGNSIMYTNVLSEIYKTQLDPTISFLH
                     EPSTKRFSLSLDIAEIFKPIIVDTIIFSLINNKRINKNDFEYQDKICYLSEKGKKKFL
                     QEFENKMQTTIKHRNLNRKVSYRMFIRLECYKLIKHFINDERYKVLKVWW"
     gene            41082..41348
                     /gene="cas2"
                     /locus_tag="PC465_001782"
     CDS             41082..41348
                     /gene="cas2"
                     /locus_tag="PC465_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HDF2649081.1"
                     /translation="MFVIVTYDIVEARSLNRIRRILRKYLTWTQNSVFEGNITEGKLH
                     KCISEIENIIDNSEDSIYVYEIKNPNSIKKKCYGIDKYSDEMFI"
     repeat_region   41532..42078
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=41532..41560
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaat"
     gene            42139..42567
                     /locus_tag="PC465_001783"
     CDS             42139..42567
                     /locus_tag="PC465_001783"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDF2649082.1"
                     /translation="MIKKLNNKDINKIMEIWEKSTIKAHDFISKEYWQNNYNTVKNEY
                     IPISDTFVYDDGDEIKGFISIIDKSFIGALFIKPKYQNLGIGGKLLDYATKKYKSLSL
                     AVYKDNKKAVVFYNKKGFNIVKEQVNEDSGFKEYIMEYSK"
     gene            complement(43022..43801)
                     /locus_tag="PC465_001784"
     CDS             complement(43022..43801)
                     /locus_tag="PC465_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649083.1"
                     /translation="MKVNENNINNIDEELDELSRKVYLESPDFWISISDKIIDKVFDE
                     MLLFFAVKYNYFNIVCFAIENNYLDLNMPSKNKKYTNIMEHLLDTSKQNEDKKIYNYL
                     LSLNKGNNLDERPILDELNCNISSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDIT
                     YKFSSKEAEPIEMCSEVSSIRCCNCDELLEDITLDKLYNLCKIQNCNNCGSNLTKVGI
                     IAKKKMNFDENTEKFKDVSTSYCCGNCDSEINLSQREHFKI"
     gene            44125..44670
                     /locus_tag="PC465_001785"
     CDS             44125..44670
                     /locus_tag="PC465_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HDF2649084.1"
                     /translation="MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIM
                     INLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALI
                     ISLLKGRNNDIKRYILITIFVGMPIIYFMGTVFMCYFNQMTVEAALFAAVVPFLIGDT
                     IKSVIASFLGTKLNNVLRRNL"
     gene            44702..45838
                     /locus_tag="PC465_001786"
     CDS             44702..45838
                     /locus_tag="PC465_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HDF2649085.1"
                     /translation="MKEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKDLIKKYEID
                     KIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKVKSGQ
                     CDLIIAGGFESSSLQPMRTYHKNDKRYNTNNPNYTVAQFSPDDNSQNSMLEGAERVAE
                     LYQIEKADLDFWVKESHKRAKEAREEKILEDIISPINNSTYDEGIRDKMSQRLLDRMP
                     SILGKETITNAANSCLINDGASFIIICSKKYLEHVKKKPKAKIINTCTIGTDATLSPT
                     SAIQAMDKLLEIESLNYLDVSAVEFNEAFAVIDVLFQRKYPELIDRYNIFGGALAYGH
                     PYGASGAIIALHLLKALEETKGRYGICSIAAAGGLGSALLLERV"
     gene            45842..47233
                     /locus_tag="PC465_001787"
     CDS             45842..47233
                     /locus_tag="PC465_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HDF2649086.1"
                     /translation="MNYYELLRIKKERHKNKNFLIIDGEKYTYENLLSYSEELGKQIS
                     LGENIPILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLDDILLKNNISIIISD
                     ESMDVIDLYDDNNNEVAKKVNFSIFNPKFNIYMYQYKKLINYLDKSICMGALSSGSTS
                     VPKVLYRTYESWAGFFPIQNGIFNISGESILFVNGTLSFTGNLNSIMSVLYEGGSIVI
                     SSGLNCKSWIRTIKQYNVTNIYLIPTKLQLLVKHLKEPVLKVVSIFTGSQLLFEDTAR
                     NLKKYMPKSEIILYYGASELNYITYLCYDELIEKPLSVGRPFPGIDIYIREGKIFVNT
                     EYAVYNATKPYSVNDIGYYDNDGYLIFEGRSDDILNIGGFKVSSTKIENEVKKIPQIE
                     DAIVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMKNEIPKKIIFLNSFPYTS
                     SEKIDRLALLKML"
     gene            47309..48184
                     /gene="dpsA"
                     /locus_tag="PC465_001788"
     CDS             47309..48184
                     /gene="dpsA"
                     /locus_tag="PC465_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit DpsA"
                     /protein_id="HDF2649087.1"
                     /translation="MSNQYDITVIGGDLRQVYMVKKLINKGYSVVTYGISNEIINGIV
                     GKSTSLAEALSKSSIILCPIPFTKNQVNIENTDDCLDATIDNLLINLSPNQILFGGNI
                     PTKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAIAEAIKRSIINIHQSNCLVLGY
                     GRCAQILAKKLYTLDANVCVGARNNDARSTANAFGYSSISLSQLDEKLLQFDYIFNTI
                     PECILTKERLEKVSQEVTIIDIASSPGGVDYSVVKEAGINATLCLGLPGKYSPKTSGE
                     ILVNAIENIINERRD"
     gene            48187..48777
                     /locus_tag="PC465_001789"
     CDS             48187..48777
                     /locus_tag="PC465_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit B"
                     /protein_id="HDF2649088.1"
                     /translation="MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVS
                     QNIDCRFGNSEEFMKKAYELTGNKPIVTIEEAEPFGPKGIADIIIIAPCTGNTAAKLA
                     NGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNC
                     KAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ"
     gene            complement(48984..49184)
                     /locus_tag="PC465_001790"
     CDS             complement(48984..49184)
                     /locus_tag="PC465_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649089.1"
                     /translation="MKKLKTISIFSLIISVILTIGGIGIVTYYVDNLFIRGLSVFVLI
                     MSSSFVSTTVRLIFEESKRYKF"
BASE COUNT        19592 a         5041 c         8432 g        16352 t
ORIGIN      
        1 aagttactaa ttgttatgta tttacaaaac tgatatatta attacataaa atctaaaata
       61 gtttgtaata ggagtatata taataaaaat tttaattaaa taaagctagg tatatttata
      121 atattaataa atatattgct ataaaagttt gtttaataaa ttaaataaag aaaagaggag
      181 aataaaatgt acaacataga tgatatgata tataattgtc cagtagaagc tttatcaaat
      241 attttaggta aaaaatgggt ggctataatt atatggaaaa tacaagaaga taaaaaacga
      301 tttggagagc tacaaagagc tataccagac tgtagtaaga aaatgttagt tcaacaacta
      361 gattttttaa ttgaacaggg gattatagtc aaccaaaaaa agttggttaa taatgttgta
      421 gagtcaacat attttttaag tgaatcagga ttacgattgc ttcctgtcat ggaaaaaatg
      481 attatgtgga gcaataaaaa tttaaattgt gataaatact aaaatttact ctgtaagtaa
      541 tgaaaattta attaagctat gagtagaaaa atgtattaaa attacataat tttttagtta
      601 gattttaatt tagaaatagg attgtaatat tggaaataaa ataaggagga attttaattt
      661 gcaaaatgta aatttatttt tagtatttat agaaggtata gtatcattct tttcaccatg
      721 tatactgcca attttaccta tttatttgag tatattgtca aatagtagtg tagaaaattt
      781 aaaagaagga aagacgagtt ttataggaag ttctttattt aaaaatacta tattttttgc
      841 tcttggaatc tcaacaacat tctttatatt gggttcatca gtaaaagtat tgagtatgtt
      901 ttttaatgaa aataaagatt taataatgtt tattggtggg attataatta ttatcatggg
      961 attattttac atgggaataa ttaaatcttc aatattgaat agagaaaaaa gatttaatgt
     1021 taagtttaaa gaaatgaaag caataacagc ttttatatta ggttttacgt ttagttttgg
     1081 atggacacct tgtattggtc caatattggc atctgtatta gtcatggttt caagttcaag
     1141 taatcatctt agtgccaatc ttttaatagc agtatatact attggtttta ttttgccatt
     1201 cataattaca gctatgtttt acagtaaact atttaaaact atagataaga taagatctaa
     1261 catggaaatt attaaaaaaa taggtgggat tatacttata gtatcaggaa tattaatgat
     1321 ggtaaatgga tttggaagta taagcaaaca ctttaatacg tcacaaaata gtaaaattga
     1381 aagcaagcaa gaagaaaata agcgagaaaa ttctactgat aaagaagaaa attctgatgg
     1441 taatgatagt caaaaagact ctaataatga caataatgat aaagggtcta atgatgaaga
     1501 tagaataaag tctattgatt ttactttaac agaccagtat ggtaaaacac ataaattaag
     1561 tgattatgaa ggcaaagttg tattcttaaa tttctgggct acatggtgtc ctccatgcaa
     1621 agaagaaatg ccttatatag aacaactgta taaagactat aataaaaata atgatgatgt
     1681 agtaatttta ggagtagctt cacctaattt aggtagagaa ggttcaaggg aacatgtagt
     1741 taacttctta aaagaccaag gttatacatt ccctgttgta cttgatgaag atggagcatt
     1801 agcatatcaa tatggaatta atgcttttcc aactacattt ataattgaca aggaaggata
     1861 tgtaactcag tatattccag gagctatgga taaggcaact atggcatcat ttattgaaaa
     1921 tcagagaaat aaataaaagt atttaagtat aagtttataa atcaatttaa ggttacaaaa
     1981 aagtgcctaa ttgtaccacc taaataatct tgttatagta aaagtataaa caatacaaga
     2041 aagggttgaa ttttatatga aaaaaacatt tgatgctata ataataggat ttggaaaagg
     2101 tggaaaaaca ttagcagggg atttggcaaa caggggatta aaagtagctt taatagaaaa
     2161 gtcaaacaag atgtatggtg gaacatgtgt aaatgtggca tgtataccaa caaaaagctt
     2221 agaaaattca gcaaacagcg taaaaacaaa gaatataaat tcttgggatg aagtacaagc
     2281 tgaatatgag aaagctatag ataaaaaaga aactttaatt acaaaactca gagaagctaa
     2341 ctataataaa ttaaattcaa atgagaatgt aactatattc acaggaatgg gaactttcat
     2401 tgatgaaaaa acagttcaag tcaaaactga aaatgaaatt tatgagttag tagcagataa
     2461 tatatttatt aatactggtt caagaccatt tatacctaat attaagggaa ttgaaaataa
     2521 gaatatagta tatgatagtg agtctcttat gaatctaaga actttaccta aaaaaatgac
     2581 aattatagga gctggattta taggtttaga atttgctggt atttatagtt catttggagc
     2641 agaagttaca atattaaact ctaataatgg cattttacca aatgaagatg ttgaggattc
     2701 agaagaaata ataaaattac ttgcaaagag aaatgtaaaa attgttaata atgcaaatat
     2761 aaaagagatt aaagaagttt ctgaattagc aatagtagaa tatgaagtag atggtaaatc
     2821 taaagaatta acaagtaata tgatacttgt agctacagga agaaaagcaa acactgaagg
     2881 gctagggcta gaaaatgcag gtatagaatt aaatgaaaga ggatttatta aagtctcaga
     2941 aactcttaag actaataaag agcatatatg ggctatagga gatataaatg gaggtccaca
     3001 atttacttat atttcattgg atgattatcg catagttatt aatcagttat ttggagataa
     3061 gactagaaca actaatgata gaaagaatat cccaaattct atatttataa gtccagcatt
     3121 ttcaagagtt ggtcttaatg ttaagcaagc taaagaaaaa ggatatgaag tattagtggc
     3181 aaagatgcca gtagaagcaa ttccaagagc taaacagatt ggcaaggcag atgggtttat
     3241 aaaaatagtg atagataaaa aatccaataa gatacttgga gctagtatga tatgtgaaaa
     3301 ttcaagtgag attatccatc ttattcaatt agctgtagat ttagaagtag agtatacata
     3361 tttaagagac cgtgtttatg cacatccaac tatgacagaa gctcttaatg atattctatc
     3421 tcctaatatg ataaaagaag tataacataa gtttaatata taaacctaaa attatcatta
     3481 taagtagatt ttagaaagag gctatctcaa aaaatagaga taagtctctt ttttactgtt
     3541 taaatgataa aaatatattt gattttataa aagaagatta tcttatgaac taaaaagttt
     3601 attttaaaac actacctatt tatgttataa acttataaat ataatataga atctattatt
     3661 ctgtattatt aagtggggtt aagcgttata attaattata aatattgaat aatctaaatg
     3721 gataagataa tggtattaaa aattatctta aaaggtgaaa taatctgtat ttaatgtagt
     3781 acagttatat ctttaaagca aggtggtgaa atgatataaa taagatatct aaaagagggt
     3841 ttgatgatag tgataaaaga tggttttcaa gtaaagaatt aacaagactt ataaaggcta
     3901 aagaagaaat agaatggtta ttaaataggg attacaaaat agacccagtc gttacttttg
     3961 ttggtgatag atatcagttt tctataagac aaagagatgc attaaaaagg gcagtctgta
     4021 ctgatgaaaa aaatattata agacaatcaa agaggctttc tctagataaa atcaaagaag
     4081 ataccgtaaa tatagatggc tttaatttga taatatccat agaggtagca ttatctggtg
     4141 gtactctagt aataggaagt gatggcaata taagagattt agcaggtctt aggggaacct
     4201 ataagattat agataaaaca gaagaagctt tgaatctgat aggtaaattt tttaataaat
     4261 acaatgcaca gaatcttaaa ttttatttag atgctccagt ttctaattca ggaaatttaa
     4321 agtataggat attagagcat gccaaaactt ggggaattga aactgaagta gaattagtaa
     4381 aaaatgcaga tgttgtattg gaaaaattag atagagtagt tagtagtgat gcagtcatag
     4441 ttgacaagtg tataagttat tttaatgtgg ctagaggtat aattgaagag tatattaaag
     4501 aatgtaatat cataaattta aataaataga taaatatagg tgagaatata taagtatatg
     4561 tagcaatatt attagtaata caagtaaagt ttgaaaatag gagaacgaat acatatcgaa
     4621 tttcataaaa tgttgtaaaa agacatatga gaggatggat atgtgtgaaa ttaactaaac
     4681 taaatattaa aaaatataga gcacctatat ataaatatgc tttagcaaat gtaaatttga
     4741 ggtctgctaa atctaccaat tcaagtatca taacagtaat acctcaggga gctaaaatgg
     4801 aagtattgga tgaagaagat gactggatta aggtgatgta caattctcaa gaaggatatg
     4861 tgtataagga tttggtatca gtaagcgaat atgcttggag taacttaaac ttaagagaag
     4921 ataaatctac aacttccaat ataattacag taattcctga aaaatctagg gttgaagtcc
     4981 ttcaagtaga tggagattgg agtaaggttg tatatgatga taaaatagga tatgttttta
     5041 attatttttt atcaattgat gggaataaac caaatgaatt agattataag tatttttata
     5101 ctgacatgat taaatttgtt aacgaaaata atattaaaag tactagcgat tatctaattg
     5161 taacagacct tagaaataaa tatacttata tttttaagaa agataatgga ggctggggac
     5221 aactttacaa gtggcaatgt actataggta agcctgagac tccaactata acaggtatat
     5281 tttatataag tggaagaaaa ccttcttttg gaacggatga gtattcagtt aaatatgcta
     5341 ctagaattaa aggtggatat tactatcatt ctgtgctata tgattcaaca ggaagttata
     5401 taatagatgg cagacttggt gaagctctta gtcatggatg tataagatta agtacggaaa
     5461 atgcaaagtg gatatatgat aatataccag atacaacaac agttataatt cattaagaaa
     5521 aattttgagt tttttattgg gataatgatt cttaaattaa taggattata tattaacttc
     5581 tcataaagag tactatttaa aaagtgtaat aagagaatgc tattaacaaa acaaagatat
     5641 tttgaggcac tctcttataa atatacataa ttaagatatt ttcataaaca attctataat
     5701 cttatcttta tcaaagaaaa caggattagc accagcacaa gcatctttca tagagttttc
     5761 tgcaagcaat tcaaaattag gattatcaac acctacatct tttaaagatt ttgggattcc
     5821 aacctcttca gaaagagctt ttatcttatc tattacaaag tcaacacact ctttatctga
     5881 tttattattt acatccattc caataacttc agctattggt cggaatttgg caggggctga
     5941 tttagcattt tcctcctcaa ctattggaag tagcatggca ttacatactc catgaggtaa
     6001 atcatataaa cctcctaatt gatgagccat agcatgtaca tttccaagac ctgcattact
     6061 aaaggcaatt ccatttaaaa aacaagcata acacatttgt tctctagctt ctatgtcatt
     6121 accattttta acagctcttg gaaggtattt aaatatctgc tttatagcat ataaggcagt
     6181 tgaatctgta acatcataag caccattagc tactacagct tctatagcat gagttagtgc
     6241 atccatacca gttgctgctg ttaaattaga tggtttgcta atcattaatt ctgggtcatt
     6301 tactgtcatt gtagctagtg aattggtatc aaccattatc atctttacat gtctgtcttc
     6361 atcagttata acatagttta ttgtaacttc agcagatgta ccagcagtag tagttatagc
     6421 tatgatagga agacattttt tagaagtttt gttgatacct tcatagtctc taatatctcc
     6481 tccattagtg gctaatatag agatagcttt accacagtct tgtggagaac cacctcctat
     6541 agttataacg aagtcgcaat tttctgattt caatatttta agtcctttat tcacattagt
     6601 tacagttgga ttttgtttaa cttcatcata aacaacaaag tctacatcta tctgagataa
     6661 aatatctgtt acttttttta cagtaccatt tgaaactaga aatttatcac taacaataaa
     6721 tgctttttta gttcctaatg atttaattga atctttagct tcattaagac atcctttccc
     6781 aagtaaattt attggtggta cataataaat gctcataact aaaatctcct tttattttca
     6841 ttgattttta tgtaaaaata tatatctaac aattttcact aatttactca taatatatcg
     6901 tatcttagat tgagataggg ttgctggttc ttatataaga acttaattcg taattacgat
     6961 tatgattaga atttaacata gtatttttat catgtcaata aaaatataaa aaatattata
     7021 aaaaaaaaca aagttactgt agttaaatca gcaactttgt ttttatagta taaatcaaat
     7081 aaatacatta gtttaaaaca aaatttttaa ttattatgtt ttgatatctt ccatatacag
     7141 aatattaatc taatttatta caatgtcttc attacgttct tccatcattg attgaatatt
     7201 tttctgagca tttaagagta atttttttat cagttctatt ttttcgtcat tagctctaaa
     7261 taaaggcagt gttacactaa cagcagctct tatacatcca ttttttctta ttggtacggc
     7321 aagacatttt aggtgttcca ttgattcctc acactctgaa gctatttgtg ttctttgaac
     7381 ttcaagaagc tggtcgtata aaacatcaaa atctgtaatt gatttttctg taaaaccttt
     7441 tagaccatct ggatataagc ttattagttt ttccttgtca aaatcacata aaagagcttt
     7501 tccaagacct gtacaattag caggtatttt ttttccaaca taagaaataa gtctaattgg
     7561 ttctggagaa tctacttttc caatataaag aacttcatta ttgtcaagta taccaagctg
     7621 acaagtttca gaacaggaat taactatatt agtcatttcg tcaattatat agttaaaaat
     7681 agttcttttt tcaaaaaatg aagaccctaa tgtgtaagaa cgtatcccta tagaatattt
     7741 ggatgtgttt ttatcaatag taatgtattt tctagcatta agtgtatgaa ctataggaaa
     7801 gatgctactt tttggagcat tgataacatc tgctatttct gtaagagtat atccattttc
     7861 ggattctgct aatgcttcta aaatatctaa tatcctagct gttgggcgat gattatctga
     7921 agtcataaat ttccccctct ttttattaat ttaaagtatt agaatatgtt gattttagca
     7981 cactatacga tattttacaa tgtagaaaat aaatatgtaa atttatatat aaataagctc
     8041 ttgatttaga tacagataga tattttttta ggctgtacat taaggaataa ctaatttcca
     8101 aaatatacct aaagaaagta agtgatattt agttatataa tttaagtaaa tatatgcaat
     8161 agtgattttt atatgtaaat atcaaaatat tatgaactta tattttatct attttttaca
     8221 ctgtataaaa actttatagt tttgaatact atataatttt aaatacgctg tatttttgca
     8281 tataaggaag tcatttgata atatacaagg tattatcaga aagtttgaaa aaattttgac
     8341 aaaaatttat tttttttatt gactcataaa taggaaaatg ctatcattaa ttcaaagatt
     8401 cgtaattaaa aatctagttc ttaaatacga accgaaacgg ccgttagaat taaagctaaa
     8461 aacttaataa gagtaattaa atatcatgtt ttaggaggat taactttatg ataatggatt
     8521 ttattaaaaa aattcctgca ggtatgatga tagtgccaat gtttatagca gctttcatta
     8581 ataccttttg cccagatatt gtacaaatag gttcgtttac gacagcagta ttttcaagtg
     8641 ttgggtctgc aactataatt ggggttcaac tggtatgctt gggaactcag cttcaattta
     8701 gagaaatgcc aaaagtttta aagagaggtg gtatacttct tggttctaaa tttgctatag
     8761 gtgctttgat aggtatactt ataggaaagc tatttggaat ggatggtgtc cttggtctga
     8821 caacattggc tgttataagt gcagttacaa atagtaatgg tagtatatat ctttcattga
     8881 tgacttcata tggagatgaa acagattgtg caactatgag tttacttact ttaaatgatg
     8941 gaccattttt tacattaata gctcttggga cttcaggtct tgcaaatgta ccattgttgt
     9001 cattattggc tgcaatagtg ccaatacttg ttggtatgat aataggaaat tttgacaaaa
     9061 aaatgaaaga gtttttagag ccagggtgta atttactcgt accttttgta gggtttgcac
     9121 ttggtagtag cataaatctt gcaagtatac taaaaggagg tttatcagga gtattacttg
     9181 gattaatatc tgtatttgta ggaggtatat ttatagtatt ctgtgataaa tttataggaa
     9241 aacgtccagg atatgcagga tgggctgtag ctacaactgc tggaaatgca attgctgtac
     9301 ctgctgctgt tgcattagtt gacccatcat ggcaaccata tgttgcaaca gctacaacac
     9361 aagtggcagc cgcagtagtt gtcactgcaa tattagtacc tcttataact agttggtggg
     9421 ctaagaagta tggatgtcct aagttcccaa aacaaaatga ggatggtaca ataacagctt
     9481 aatttatatt acagtgagtt gttggtaaaa taataaattc tttaattaga ttttaggata
     9541 ttaataaaat tatattattt ataaaggaga gcaagaataa tgataaatgc agtgataatt
     9601 gatgaaaaag ataatgttgc agtagctatt gaagcaatag ctaaaggtag tgaaattagt
     9661 tttaaattaa aagacaaaac agtaaaaacg attacagcac tagatgatat aactatttat
     9721 cataaattgg ctataaaaga tatggccaaa ggtgataaag ttactaaata tggtgaacat
     9781 ataggagaag caaatcagga aataaaaagt ggtcaacatg tacatattca taatgttaga
     9841 agtgttagag aggatttgga taaacaagtt atgactaata tataaaataa tatttataga
     9901 gttataaaag ttgtattcat tgcttttagt gtcaaatagt ttttaaatag gtttttagct
     9961 gtttgattag tgagtgtaat aaaaattata atatataaaa attataaaaa gtatatagac
    10021 tattttagga ggaaatcagt atgaaatttt atggatataa aagaccagat ggaagagttg
    10081 gtataagaaa ccacatatta atcttgccta cgagtgtgtg tgcatcagat acaactagaa
    10141 taatagcatc acaagttcaa ggggcagtta cctttaataa tcagaatgga tgttcacaag
    10201 tacattcaga ccaacaatta actatggatg ttatggctgg ttatgcagca aatccaaatg
    10261 tatatggtgt aatagttgta tctttgggat gcgaaaattg ccaaaatgat ttggtagttg
    10321 atgcaataaa agagagaaca aataagccaa taaaaactct tgtaatacaa gaagaacatg
    10381 gaactttaaa aactatagaa aaagctgttc gttatgctag agaaatggca caagaagctt
    10441 ctttgcttag aaaagaagaa tttccaatat ctgaacttat actaggaact gaatgtggtg
    10501 ggtctgaccc aacaagtgga ttagcagcaa atccattaat aggtgaatta agtgataaac
    10561 ttgtcgattt aggagcaaca tcaattttaa gtgaaactac tgaatttata ggtgcagagc
    10621 atatactagc taggagagca gtaaatgaag aagtaaaaga aaaaatatta catatagtac
    10681 atagatatga aaattcatta aaattggttg gagaagaagt tagagaaggt aatccatctc
    10741 ctggaaatat agctggtggt ttaacaagtt tagaagaaaa atcacttggt tgtatacata
    10801 aaggtggtca tagacaaata agtgaagtat atgattatgc caaacaaatt gataagaaag
    10861 gccttgttat aatggatacc cctggaaatg atgcttcatc tgttgctggt atggtagcag
    10921 gaggagcaca aatagtggta tttagtacag gaagaggaac accatcagga aatccaatag
    10981 caccagtaat aaaaataact ggaaataaaa taacttttgc aaatatggaa gataatatgg
    11041 attttgatgc tagtccagtt atatatggtc cacaaacaat ggaagaatta acagatgatt
    11101 tgttaaatat ggttgtagat gtagcaaatg gaaaacaatc aaaagcagag tcccttggat
    11161 atactgaaat ggcaatagct agagtatgca actatgtata atctttaagt aagaaaataa
    11221 atacatagaa ttttaataaa gggtgagatt atgaagtttg taagttttac tgaaggagaa
    11281 aatgaatgta aaagaactgg agttttttct aaagatgaat tatttattat agatgttaac
    11341 tctttaaatc tcagtagaaa ttttaaggat ttaaatgaat taattcaaaa tgtatctagt
    11401 gaagatatta ttaagttgaa aactattata aatgaaagta cattctataa ttatgatgtt
    11461 tttaaaagag agagatgtac tgtacatgtt cctatagaaa aaccaataca tgatatctta
    11521 tgtgtgggag tgaactataa agaccatctt gaagaaactc aaactcactt tgatgatagt
    11581 tttgaagaac cacaaaaaac ggtttatttt acaaaacgtg tgacaaaggc aataggtcca
    11641 gaagatgaga tagatggtca ttttgagata aataatcaac tagactatga agttgaactt
    11701 ggagtagtaa taggtaaaac aggtgttaat attagaaaag aagaggtaga agattatatc
    11761 tttggttaca ctgttataaa tgatatttct gctagaaagt tgcaaaaaga acatgttcaa
    11821 tggtttagag gaaaaggatt agatacattt acctctttag gtccatgtat tttacataaa
    11881 agtgcagttc cttttcctat aaaacttaaa gtatgtagta gggtaaatgg tgaagaaaga
    11941 caaagttcta atacaggatt attcatatca gacgtttcag acatagtttc agaactttca
    12001 aaaggtatga ccttagaggc tggagacatt atagctactg gaacaccttc tggagtaggg
    12061 atgggatttt cacctcctcg atatatgagt agtggagatg tagttgaatg tgagattgag
    12121 agtattggaa ttttaaaaaa ttacattaag taactgtttt aatataatta atattaaagc
    12181 taaatctgat gtattaatga acatattaaa ataaatttta ggagtttaaa ttatgaaagc
    12241 agaatttttg acaccagttg ttacaatatt tgatgaagaa ggaaatttag ataaagaagg
    12301 taataaaaaa gtgtatgacc atcttataga tggaggtgta gatggactag tcataatggg
    12361 aagtactgga gagttcttta atatgtctat ggatatgcaa aaagaactta tagatttagt
    12421 aactagtcat gtaaataaga gagtaaaagt gtttataggt acaagtcgta tgtgtataaa
    12481 tgaatctata gaactttcaa actatgcaca taatagtgga gcagatggtg ttatgataat
    12541 aagcccttat tatttctctc ttgatgatga tagtattgag ttattttata gtgaaatagc
    12601 taagaataca gaggctgaaa tatatttgta caattatcca gatagaactg gttatgattt
    12661 aagtccagaa cttacattaa gacttgcaag aaaacataaa aacatagttg gatataagga
    12721 tacagtaact ttgatgggac ataccagaga tttaataaat actatgaaag tagagttccc
    12781 agaatttaag gtttatagcg gttatgatga aaactttata cataatctaa tgtctggggg
    12841 agcaggttgt atagggggat tatcaaattt aattccagaa gtttgctcca aatgggctga
    12901 agcttacaat aatagagata tggagaaggt tatagaaatt caaaaatata ttaataaagc
    12961 aatggatttt tacttaataa ccaatccatt tataccagca atgaaaaaag ctatgaatat
    13021 cagagggtta caaataagtg attatatgac tgctccattt gtaaaaccaa atgaaaaaca
    13081 agtatgtgaa attaaaaaat tgatgaatga attaaatata tgttaaatca accttgcaaa
    13141 gaggtcaaca ataaattaca attatcttaa taaaaattaa attaaaataa tactagggta
    13201 ctatattagt ttaataggga aagtgatgaa aattcactac agcccccgct actgtatacg
    13261 gatacgaaat caaaatccac tgaaatttat aaaaattttg ggaagggtga tggaggaaaa
    13321 gccgtgagtc aggagacctg cccagtatta tataagttca atttagggtg gagattgtaa
    13381 tttataataa aatgaagtat caattcgttt ttgtaaagtt gatatatgaa cttctcctta
    13441 ttaaattagg agaagttttt tattttatta aaaggttata cttattaaag atgactttag
    13501 gataacttta ataagtatac tttaaaaagc atatattatt aaagtttttt agccactcat
    13561 aaaaaataag atattggagt gaaagagatg aaatttaaat caaatgtttt aaagcaattt
    13621 tttttaattg ctatggtaat ttttatggta ggaggtctta tagggtgtag taaaagtgac
    13681 aaagagaata aacaagctag tactggtaag aaattagaat taaaatatgc tagtggattt
    13741 agtgttgaag atttagaaga tggaattaaa aaagtaactg atggagataa tcgagaactg
    13801 attttaatcc caaagaagat taaaattcct gaaaaatata aaaatgctaa tatagttaga
    13861 acgcctgtgg acaatgtatt aatagcatct acaacacagg cttgttctct gagaacaata
    13921 gatgaactag atagtataaa agcagtaaca acagaagagc agtactggac tattaaagaa
    13981 attaaagatt taatgaaaga tggaaaaata cattacgttg gttcaaattt agcaccagat
    14041 tatgaaaaaa tagtagactt aaatcctgac ttaactatag ttagtagtgg tttatcagag
    14101 gctgatacaa aatttattga caaattaaaa gaattagggc ttaattatgt tgtagacaat
    14161 gagtataaag agcaaaatcc atttggaaga atggagtgga caagtttaat agctgcattt
    14221 tatgataaag aagatatggc tactagtgaa ctaaataaaa ctgtacaaaa ggtagaagaa
    14281 gtaagtaaaa aaataaaaaa caaagctaaa cctaaagttg tatgggcatc tgtatatgaa
    14341 ggaagtgctt atatagctcc taaagattca tatgtggata atatgataaa aatggctggt
    14401 ggaataaatg catgtgcttc aatagattca aatgaagggc gagtaagtat tgaacaattg
    14461 catgaagttg caaaagatgc agatatattt gtatactcat caagttcaga ttatgcacca
    14521 aatttagatt ctataaaatc tagtgcacct gtattggctg atttggatgt tgtaaaaaac
    14581 ggaaacctat gggtgtttgc tccagattat tatcaatcag tagataagac agacgaatta
    14641 atagtagatt tagttgagat gttccaccca ggtactacag gtgaaaaaat caaacattat
    14701 ataaattatg ataaatagta cagagaggac acaaaaagat aggttttata gattttagtt
    14761 aatatagctt tgctaagagg agtatacaaa tggattttat caataaaatg agaataagga
    14821 atacgacaat atttatagta ttaattataa gtatgatact tactttttta gtgtgtgtag
    14881 catttggctc tgtaaaaatt gaatttaaag aagtaataga tgttgtatta agaggtatgg
    14941 ataatacaga acattataaa ataatataca atataagaat ccctagagta cttgcaacca
    15001 tggtaggtgg agcatgccta gcagtatcag gtattttatt acagatattt tttaaaaacc
    15061 caatagttga accgtatata ttaggagtat cttcgggttc tactttatca gtagctctca
    15121 tgattttggg aggatacaca ttgggatttg agagtgtaaa ttcaatgagt atatttgtag
    15181 cagcttttat aggagcttta attgtaatgt ctatagtcat tttatttgca aataaggtaa
    15241 agaatataac aactctttta ataataggaa ttatgaccgg atatgtatgt agtggtataa
    15301 caaatgtgtt acaatcattt gcaaatagtg ataaattaaa agaatttact atgtggtcta
    15361 tgggaagttt ttctggattt acatgggaaa aggtagaaat acttataata gttggtatat
    15421 taggtctttt gatgactgta ttcataataa aacctttaaa tgctttttta ctaggagaag
    15481 agtatgcaaa aagtattggc ataaatataa gattttttag agttttgata gtatttatat
    15541 ctagtatatt agcagcaata gtatcagcat ttgcaggacc tatagggttt attggacttg
    15601 cagtgccaca aatttcaaaa atgatattta aaacatcaga taatagagtt ttgataccag
    15661 tagtaatatt tttaggcagt atagttacag ctctttgtga tttaatatca agagtaattt
    15721 tatcaccagt agaattacca ataagtacga taacatcttt attaggagct ccaattgtag
    15781 taatgttatt ggtgaaaagg aaggataggg cttagacatg ttgaaaacta ataatttaag
    15841 tgtaggatac aataacaaag ttgttataag taatataaat gtagaagtaa aaaatggaga
    15901 aatactatgt cttttgggaa gtaatggagc tggaaaaact accctattaa ggtccttatc
    15961 taaacttata tcaccaataa aaggtgaaat atatttgaat ggtgtaaaca taaattgtat
    16021 atcaagaaaa gcattatcaa aaaaaatggc tttagtactt acaaatagat tattaggtga
    16081 tttaatgact gtacaagata tagtcaatat aggaaggtat ccatatacag gattttttgg
    16141 gagtctatct aagaaagatt taataatggt agatgaagca ttggagtctg tagatgcctt
    16201 acatttaaag aaaagatatt ttgatgaact aagtgatgga gaaaaacaaa aggtgttggt
    16261 tgcaagggct cttgttcaag aaccagaaat aattatatta gatgagccta caactcactt
    16321 ggatataaaa catagattgg aactcataaa catactgaaa aaattaagta aagaaaagtc
    16381 aatatcagta atactttcat tgcatgaaat agacatagca ttaaaaagtt gtgataaagt
    16441 tgctcttata aaaaataata aagtcatagc ttatggtcag cctgaagatg tagtagatga
    16501 ggatattata aattcgcttt atgaattgga tgataaaaac tttaatagtc ttttaggttc
    16561 agtagaaatt agtaataaat ctaaaaatga agtttttata attggtggtg ggggtaaagc
    16621 aacaccaatt tatagagctt ttactaaaaa aggtataggt ctgtattctg gaataataca
    16681 tgaaaatgat attgattatg aaattggtag aactatgggg ataaagatgt ttacagaaaa
    16741 tccatttgag cctataagtg atgagagttt cgatttggct attagaaatt taaatgattc
    16801 caagattata atagatacag gatttagtgt aggagagaca aataagagga atatagatat
    16861 tataaaagag gctttaaaat tggataaaaa agtttattct tttagaaata gagatgagag
    16921 taagaagtat tatgacagtt tggatagtaa gatagaacat atagataaag tttctcaaat
    16981 aatcaatagt gcagatataa ataatttatt ataatttatg aaataaaatg tacttatgtg
    17041 ctatagaaaa aagagtatag attataattt ttttgaaatt acaatctata ctcttttgtt
    17101 attttgttta tgtatttata tatttataaa actttagcat tttatagata accaatagct
    17161 tcctctctag ttaaaaaaaa gtgaatccct gtagtcgatt ctttccatct attttcatta
    17221 aaatcttcag ctacaatcgt ttctcctact ctatatataa aattttcatc agcatatgca
    17281 cgagcacttt taaaagattc tttaccatct atactagtaa ttgacagtac ttttgcctta
    17341 tcacatctac aagcgtttga tgtagcagac actctttttg cgtcgctggg tattaataat
    17401 tgtaccattc taaaattaaa acatttttta tagcctataa atgctcctgt ttcaggacaa
    17461 tacaatttaa aaaaacgggt actttcatct gatattactc catttaaagt agcatgttct
    17521 aaatttgaat tttctaaatt agctcctcta atatctgagt tagataagtc acaaaatcta
    17581 aaacttgcac cacttaagtc tgcatttttt aatatagaat tttttaatga acaatccgaa
    17641 agataagaat tattaaaaat agagttttct aaatctgctt tttctaaatt taaattgata
    17701 aggtcagacc acgaaaagtc aatattactt aagcagtatc ctcttaagtc catattttct
    17761 aatcttaatt cttttaaatc tgccttttct ccagcattat tgtttttaag ccataaataa
    17821 tgtttctcaa gtgttttttc taattcttgt ttagaaatag ttttcattaa aatcaccttc
    17881 ataaatttat ttttatatat gtagtagcaa aatagtcata tatttaatta tataacaata
    17941 aataaaaaac ttctaaataa tatataaaat atcatcttga aagtactttt ttcaatatat
    18001 cagaatatat ttttaagcta tttagagata atttaaattt ttaaacagga cataataagc
    18061 ttgtattgtt ttatatttga gttgataaaa atttctttaa ataaaaataa tgtcaattat
    18121 aaagtaataa aagtttagat ataaaaaaat ttgtgtatat actatatgta gtatataata
    18181 gataaagcac tgactatatg tagtgctttt gtttttgaaa aatacttatt gcatttctat
    18241 aattatagat taattttggg atttcaactg ataagtacca aaagaaataa taagcaaatt
    18301 aagtgaaatt atggcacaag attatgttaa aaggacggta aataatgaat tggatagagc
    18361 ttaacaatca agtgataatt aaaaatgaac aaggcaagta ccaattggaa aaggataagg
    18421 aagccttaag tagttacata gaagcattta tacagccaaa gttgagaaaa tttaataacc
    18481 tagaagaaag attgaagtat ttaatagatg aaggttatta ttcaaaagaa gtaataaatc
    18541 agtatagcat agatgttatt aaaaatatat atgatatgat tgataaacat aagtttgaat
    18601 ttcaatcata tatgagtgca aataagtttt atcaaaatta tgcattaaag agcaatgatg
    18661 gaaaggaaat attagaaaca tataatgata aagtgttaat tgtagctttg acactaggaa
    18721 atggcgataa agatttagct ttaaacttgg cagataaaat agtaaaacaa gaatttcaac
    18781 cagctacacc tactttttta aatgctggaa gaaaaagggc tggagaaatg gtatcatgtt
    18841 ttttactatc tgtagaagat agtacagaag gtatatcgta tgctatatct tcatcaaatc
    18901 acttatcaaa gattggtgga ggagttgcac taaatttatc taaacttaga gcatctggcg
    18961 aatctatcaa agatatagaa ggtgcagctg gaggtgttgt tggagtagct aaaatgttag
    19021 aacaatcatt tagttacttt aatcaaatgg gagctagaca aggttctggt gcggtgtacc
    19081 ttactgtatt ccatcctgat tttgaattgt tgatggatac taaaaagata aatgcagatg
    19141 aaaaaataag gcttgctaca ttatcattag gagctataat accagataaa tttatggagt
    19201 tggcagaaaa aaatgaagta gcatatgcat tttatcctca tactgtgtat aagaaatatg
    19261 gagtttctct tgatgagata gaaatggatg agtggtatga taaattggtt aatgatagtg
    19321 atataagaaa aaaagaaata aatcctaggc agatgttgac aaaaatagca cagatgcaac
    19381 aagaaagtgg atatccatat gtagtgtaca tagatacagc taatagagaa catacattaa
    19441 aagatgttgg aattattaaa atgtctaact tatgttgtga gatatttcaa tatcaaacac
    19501 cttcagaaat agagggatat ggaggaaaaa atgaatgggg acaagatata agttgtaacc
    19561 taggttcttt aaacatagcc aatgtaatgg ataataaaac tatagaaagt acagttgaaa
    19621 cagcaataag agcactgtca tttgtagcag atagcacaga tataaaacca gtgccaacgg
    19681 taagcaatag taacagcaag tctcattcta taggattagg agctatgaat ttacatggat
    19741 acttagtaag agaaaatatt ttatatactt cagatgatgc tatagatttt tctaatgtat
    19801 tttttgcaat ggttagatac tattcaatta aagcttctat gaaaatagct atagaaagaa
    19861 atcaaacttt tgaaggattt gataaatcag aatatgttaa gggaagaaat agcaaggttt
    19921 tatcaaaata ctatgaacaa tcttatctac ctaagtcaga aaaggtaaga gcattatttg
    19981 aagggattta tataccaaca aaagaagact ggacaaaatt attggatgag gtaaaagaaa
    20041 aagggatata taatgcatat ttaatggcag tagcaccaac tcaaagcatt agttatgttc
    20101 aaaatgctac atcaagtata atgccaatta ctgagccagt agaagtaaga acatatggag
    20161 actctactac aatatatcca atgccatttt taacaaatga taatatgttg tattatcaat
    20221 cagcatacag gatggatatg agaaaggtca tagatttagt ggcaacagtt caaaaccatg
    20281 ttgaccaagg tatatcaaca acactgtttg ttacagatga aaagacaact agagatatag
    20341 ctagacatta catatatgcc tataaaaaag gtttgaaaag tttatattac acaagaacaa
    20401 agatgacaag agatactcat gagtgtctag tgtgttcagt atagggagag aaatatatga
    20461 catttaattt acataaaata cataatgcag ttaactggaa tagagaagaa gatggattta
    20521 cacaagcttt ttgggaacaa aatgtaaaac aattttggct tcctgaagaa atatctgttt
    20581 ctaaagacat aaaggtatgg aatgaactaa gtaataaaga aaaggaatta tataaaaaag
    20641 tattgggtgg tttaacatta ctggatacaa aacagggaaa taatggaata ccatctatga
    20701 tgagtttaac agaaaaccta caaagaaaag ctgtcttgtc ttttatgggg actatggaag
    20761 aaatacatgc aaaaagttat tcttctatat ttatgactct actttctaat ttagaaatag
    20821 atgaattatt tgaatggata gaaacagaac caacattaca aagaaaggct gatttagttt
    20881 tagctcaata cgaaaatact acaaatcaag agggattata cctatcaatg gttacaagtg
    20941 tatttttaga gagtttcttg ttttattcag gattctttta tccattgtat ctatctggtc
    21001 aaggaaagat ggtagctagt ggagaaataa tatcgcttat tcttagagat gagtctttac
    21061 atggtaagta tataggattg ctagcacaag aaatatacga ttcatttgat aaaatggata
    21121 aggagatgtt agaagagaag atgtattcta tactttatag ccttatggag aatgagatag
    21181 agtatacaaa tgttatatac agagaaagtg ggcttgaaaa agaggttgta aactttttaa
    21241 aatacaatgc gaatagagct ttagaaaatc tagggtttga gaagctatat actgtagatg
    21301 ctataaatcc aattgtatta aatggtctta gcactgaaac caaaacacat gatttctttt
    21361 caactaaggg taatggatac caaaaaggag tgtatgagga attagaggat gaagatttta
    21421 taatataatt tataattatg acacactgtt gtcactttta gcgtgataat atcaatgtat
    21481 aaaatatata tggaggtatt tttatgaaat atgaatggag aaaaagagat aaagagttat
    21541 atttacctaa aaagaatcct gtaatagttg aaataccaga acagaaattt atcatgttaa
    21601 aagggagtgg agacccaaat tctaaagaat ttactgaagc aataggagta ctttattctt
    21661 tggcatatgc aataaaaacc atgcctaaaa aaggaattgt accagaaggg tattttgact
    21721 atacggtttt tcctttagaa ggtatatggg ataagggaga aaaaagtaaa ggcttagatg
    21781 tacttattaa agaagattta atttacacta taatgatacg tcagccagat tttgttacac
    21841 aagacctgtt ggataaagct actgatatag taaagaagaa aaaacctcat aatcttcttg
    21901 aaaaagttag atttgggtct attaatgaag ggctatgtgt tcaaatgctt catataggtt
    21961 catatgataa tgaaccagaa agctttgaca ttatgaacga attttgcaaa aaaaataaac
    22021 ttataagaaa atcttacaca catcgtgaaa tttatataag tgatgctaga aaagtatcgc
    22081 ctgaatcatt gaagacggtt ttacgttttg aagtagaaag ggaagtataa atattttgaa
    22141 taatttataa gagttataaa aagtgaagtc tgttgagact tcattttttg atgcaatttt
    22201 aaaattaaat ttgatgtttc ataatatttt aaaaactttc tacttttatt agtgtgaata
    22261 actgttgcta ttaaataata atactaatta tataagtatt attatataat atttatagat
    22321 tattatataa gtagattatt agtaagatgt atgcattatt aattaaaata aattacatat
    22381 actatttaat atttcattta aaatattaaa aaatgtagat aaaaattgtt ttattaagaa
    22441 aaaattaata tattgacaaa atttaagtgc tcatttaaac tattaattga taataatatt
    22501 caatattaaa taataggagg cgttatgaat aaatatcttc taataaatcc agtggcagaa
    22561 agaatgtatg gagaaaagtt tcaccttatt aaagcaaatt tgataaaaaa ggggtacata
    22621 atagcagaat gtgaaccaca gttagaatat gtaaaaaagc agtacaaaga gtatacaaaa
    22681 aagactaaaa atacaatgtt ggattgtaga tgtccagaaa gtataagtct tttaaaaaga
    22741 aataatttga taaatgattt tgaagtacct atgatagaac caatattagt aaggacttgt
    22801 agggttttat acgataaata tataaaaagt aaagatgata tgttggtagt aacctgtcca
    22861 tgtacacaat taagagactt tgcaagtgaa aagtttaagg ataagggtaa tgctatgttt
    22921 tatacatgga aagagtttgc tgaacaagaa ggtgtaaaat cacttggaaa aatagatgaa
    22981 tcaccaattc cattaggata tttcaaagat acttttgaaa aagttcttga agtatcaagt
    23041 gaagacgaaa tattaagtga aatacaaaaa ataagaaatg gctttgaaga taagtatgac
    23101 atagtagaaa tgttttattg taaagatggt tgtaataatg gagatggttt gtaaatggtc
    23161 aataaattta ataataagtt tttaaggcta gtaaagagtg ttctgatatt ttttataatt
    23221 cttttattat ggaaaattac aaattatctt ggtatttgga gtgattatat attaccatca
    23281 cccgaaaagg tatatagtac atttttaaat atgataagtg atggttcaat atttattaat
    23341 gtatatgcaa gtatgaaaag agttttgata ggttttgcaa taagtactgc tataggtgtg
    23401 cctttaggga tattctttgg aatttatagt ggagtatatg aatactttaa atctctaata
    23461 aattttttaa ggaatacacc tccccttgct ttaataccaa tgcttatatt atggtttggt
    23521 ataggagagg aatcaaaaat tataattata gttttagcat cctttttccc aatctttaca
    23581 agcacattga aagggattaa aaattgtgac tcaaaactga ttgaagtggg tagagtattt
    23641 gagttttcaa agcttcagat aatatttaaa ataataatac caaatgccat tcttgatatt
    23701 gctgttgggt taaagttagc tcttggatat agctttagag caattattgg ggcagaactt
    23761 gtagcagctt catctggtct tggatacttg atatctgatg gaaaagaaat gtctagaaca
    23821 gatgttgtta ttgtaggtat aatcgtaatt ggacttttag gaataattac agattacata
    23881 ttttcgatta ttgtgaagaa ggtaagtaag ggaaagatgg tggaagcata tgaataattt
    23941 agtatgtgac tctggatata taattagaaa tttatataaa agttataaag ttgacaatga
    24001 agaacatgta gttcttagtg atatctcttt aaacatagat agaaaccata taacagtaat
    24061 tttaggtgaa agtggttgtg gaaagactac cttgcttaga gcaattgcat cacttgaagg
    24121 tataaatagt ggtgaaatta ggtttattaa tgataataaa gagtatagac ctaatgttgg
    24181 ttttgttttt caggagagca gattaatgcc ttggttaaac gtaagtgaaa atatagcttt
    24241 tcataatcaa agaaaaaata ctattttaaa caaggtgctt agaaaattta aacacaataa
    24301 aagaattagc agtaaaatta taaatgataa ttttagaagc ttagaaacaa atgataattt
    24361 gaacaaatca aataaatata ataggaaaag taatattgat gtagaaaaat atcttaagat
    24421 gatgaacttg cagaaattta aaaactctta tccaaatgaa ttgtcaggag gtatggcaca
    24481 gagagtaagc atagctagag ctctttcttt caatccagat atgttgctta tggacgagcc
    24541 tttttcggca ttagattatt ttacaaggat tgatatgcaa aatgaagtta taagaataca
    24601 taagtcaact aataaaggcg tgatatttgt aactcatgat attgatgaag cgttaaagat
    24661 aggcaagaaa atagttgttt tcacagacga aagaaaaata aaagaattta atatagaaga
    24721 tggttataat agagatttaa cttcagatta ctatattaaa ttaaaaaaag atattttaat
    24781 gacaatgaaa tcaaataaag gcatttaaag aaattaataa tattttaagg agtaaagtaa
    24841 atgaaattaa aaaagctatt gataggtata acgatattaa cacttgcaac agcatcttta
    24901 gctggatgtg ctaaaaaaaa taatggagaa aaactttcag aaataaattt aacttatgta
    24961 aaatcaccat taaatgttcc ttctataatt cagaaacagg atgatttatt tggaaaggaa
    25021 tttaaaaagg ataatataaa agttaacttc cacgaaatta ctacaggtcc agagcaaaca
    25081 caagctttag ctgctggaga aatagacttc ttacatgcac taggtggtac atcagcttta
    25141 atagctgcat ctaatggagt agagttaaag atattaaaca cttatagcag gtcaccaaaa
    25201 ggatttatga ttttgactaa taataattca ataaaatcag cagcagattt agtaggtaag
    25261 aaggtggcag gcccaaaagg gactatatta catcaggtat tgatttcagc acttgataaa
    25321 gaaggattaa gtatggatga tgtggaattt gttaatatgg gtattccaga ggcatcagca
    25381 gctctttctg atggcagcgt agatgctgca ttgattgctg gtccagcagc tcttaaagct
    25441 atgaagtcag gtagtaaact tatagcaaat ggtgaaggtt tagtagatgg tataatagta
    25501 actgctgtta gcacagactt tgcagagaaa catccagaaa tagttgaaag atttatgaag
    25561 gttgaaaagg aaactttaga atatgtaaat aataattttg atgaagctat ggaaaaagta
    25621 gctaaagaag ttgatttaag tcttgaagaa actaaagaat tatatgcttg gtatgatttt
    25681 agtttagata taacagataa agacatatct tcgcttgaag atacacaaga cttcttaata
    25741 aaaaataagt tacaagagaa aaaagtgaac ataaaagaat taatctataa tgctaagtag
    25801 aaactatgat aaaataatac taagtaagaa atataataaa agtttaagtt accttattaa
    25861 ggtaactttt tctattttga attagtaatt tcaatttatt ttagaatgat tagttgataa
    25921 taatgattaa ttaatcataa aaagatactt ttttatagag ttttattaag atgtctaata
    25981 atatggttat acttatgaag tcagtaattg tgaagttagt aatatgatta aatttatata
    26041 ttgtaaaaag attataatat attaaaattg gactgttata taatgagtaa ataggtatat
    26101 taggaggaat tatatgagtt ataaagtata tattgtggaa gatgatatat caataagtac
    26161 attacttaaa gattatattg agaaatatgg atttgaagtg attgttgaag aaaactttga
    26221 tgatataatg attacatttg aaagttttaa gccacactta gttctattag atgtaaattt
    26281 acctaaattt gatggtttct actggtgtag atgtattagg caacagtcga atttacctat
    26341 aatttttata tcagctagag atggtaatgt agaccaaatt agagctttag aaagtggagc
    26401 agatgattat ataacaaaac ctttttacta tgatgtagta atggcaaaaa taaagagtca
    26461 tataagaagg gtatatggtg aatattcacc taaaatagac gaaagaatag tggagctaga
    26521 tggattaaag ttttatccag aaaggttaga actagaatta aatggtgaga atctaattat
    26581 aactaaaaaa gaaggtatac tgattgaatg tcttatcaag agatacccaa aagtagtaag
    26641 tagagattat cttttagaaa agatatggga tgatattgag tttgtagagg aaaatacttt
    26701 aaatgtaaat gttagcagga taaggaaaag atttgaggaa ttaggtatag ataatgctgt
    26761 tcagactgtc cgagggttag gatataaatt aaataagaat tggtaaggag aaagtatgaa
    26821 gttattttta aaagattata aaggttatat ttttatatat tatataggca tagttatgac
    26881 aattatttac tgtaatctta tgaagtttat tagttttgga gagagtttat atattctttt
    26941 atttagttct tttatattgt tatgtttttt aatatataag tattataaaa atagagaagt
    27001 atataatctg tttgaaaaag gagtacattc tttggaggag tcatttttgt atttaggaag
    27061 ctcattcttg gggagaaata tatcagttat tttaaaacaa caacataaat tgtatcaatc
    27121 aatgatacaa gagcataaaa agatacatag tgaacattta actttcatca accaatggat
    27181 tcatcagatg aaaacaccaa tatcagttat aagccttcag cttcaagatt atgagggaga
    27241 agaagtaact gaaaatataa gaaaagaaat agatagatta aataaagggt tagatatggc
    27301 tatgcatttt gcaagggcag ataattttca gaaagacttt atagttgaaa aagccaaatt
    27361 aaatgaaatt gtatctagta ttgtaaatga agaaaaaagg ttatttataa aaagtggaat
    27421 gattcctaag attcaagtag acaaatttac ttatgtttat acagatgtaa aatggatgaa
    27481 atttataata ggtcaattaa ttacaaatgg agtgaaatat tctaaagatt atagtaacta
    27541 cctaactata aaatctgaag aaaataataa atatgtaatt ttaagtataa tagatgaagg
    27601 aattggaatt gtttctaaag atttaaaaag ggtatttgac ccatttttta caggagaaaa
    27661 tggtcgtaag tttggagaat ctacaggtat gggtctttat ctagtaaaaa aggtatgtga
    27721 tgatttaggt cataaagtaa gtataaaatc agaagtagga aaaggtacag aagtttcaat
    27781 ctactttaat aaagatgtaa atagtttaat aaaggtgtaa attatctgtt acaatagggt
    27841 ttttagttaa ttgtactttt ttattataca atttattaaa tgaaatattc atagttaaat
    27901 aatcaaaatt taagagagtt tatttgcaaa ccttacatag atgtaaggtt tgtgtaatgt
    27961 ttgcagatag ttaaattttc taatctaaat tacaattaat ataagaaata acataagaga
    28021 aataacataa aaaaagaaat tttgtaaaaa aggaaggatg tttattgatg agtttagatg
    28081 ttatttttat attgaaatca gtcataatag ctatagtaga ggggcttaca gaatttattc
    28141 cagtttcatc tacaggtcat atgattttgg ttggtaattt aatagatttt aaggggcaat
    28201 ttgctgaaat gtttgaggtt gtaatacaac ttggggctat attagcagta gtagtacttt
    28261 attggaaaaa gataaaagat agcgttatag aattttttaa atttatattt actggcggaa
    28321 aagaaggaaa gattggtttt agatttggaa tgaatgtaat tataggttgt ataccatttg
    28381 cgattatagg agttctattt tacgataata taaaatcatt gtttaattta caatctgtaa
    28441 ttataggatt tatagtgggt gggattttat tattagtagt agaaactttg tttagaaaaa
    28501 agaatcattc cacagataat atagataaaa ttactccaat acaagtttta aaggttggga
    28561 cattacaagt tttgtctgca tggccaggta tgtcaaggag tgcatctact attatgggtg
    28621 gatggatagc aggacttaat tctcctacag cagctgagtt ttctttcttt ttagcagtac
    28681 cagctatggt ggcttcttca ggaaaagatt tatttgaatt tgattattca ataatgacac
    28741 caacattgtg gattgctttg gtagttgggt ttatagtagc ttttattgta tcaataatag
    28801 ttatggaaaa attcgtgaat tttttaaaga aaaaaccaat gagagtgttt gctgtataca
    28861 gaataatcat gggtgtagta cttgcagtat tagcttttac taacataatt agtgtataga
    28921 aaaaatagat ttattatcta taaaaattaa actaagataa attataatta acaattatat
    28981 atatgttatt tcaaaaatta aattaggaag gatagttaaa taatgaaaat tttaactgta
    29041 aataatttaa gtaaagtata tggtaaaaaa ataattttca acgcattaaa tgacataaat
    29101 tttagtatag aagatggaga atttgtagga attatgggtc catctggtag tggaaaaact
    29161 actcttttaa atatgatttc tactattgac aagccaacta caggaactat ggaattaaag
    29221 ggcaagaatc ctttattgtt aagaggtgag gaacttgcat tatttagaag aagagagtta
    29281 ggttttgtat ttcaggattt taatttattg gatacattaa ctataggaga aaatatagta
    29341 ttgccattga cattagataa ggtcagtgta aaagagcaag atgagagatt gaatgaagta
    29401 tctacaatat taggtataaa agatttatta ggaaaaagaa cttttgaagt atcaggtggt
    29461 caagctcaga ggactgctat tgctagagca ttgattaaca atccatcaat acttttagca
    29521 gatgaaccaa caggtaattt agattcaaag tcatcaaagg ttgtaatgga gctatttcaa
    29581 aagataaata aagaaaataa agttactact atgatggtaa ctcatgaccc attagcagcg
    29641 agctactgta gtagaatctt attcataaaa gatgggtata tatataatga aatatataag
    29701 ggtagtagta gagagcagtt ttatcaagag ataatggatg tacttacatt attgggaggc
    29761 gataactaat gaatataaaa cagtttgcta ttaacaatat ttcaagaaat attaaagcgt
    29821 atttaggata cttagcaagt attgttatat catcttcact gctattttct tttattatgt
    29881 ttacaagtca tccagattta gatgtatctc aatttcctga ttatttaaaa gaaggtctca
    29941 agatgagtaa gataattgca tatctattct tattcttctt tgtgttttat tcagttagtg
    30001 tgtttcttaa aagtagatat aaagaatttg gaatacttta tattacaggt atatcaaagc
    30061 gccaagtaat gaaattaatc tttatagaaa atatgataat aaatatagta tcttctgtaa
    30121 ttggaataat aataggctta atctttgcaa agatattttt agtggttatg tctacttttt
    30181 tagaattatc accattaaaa ttctatatac catttaatgc gatattgtct actttaatct
    30241 attttatgat tttagctgta ttaacatcaa tatttacttc ttttatagtt aaagaaaatc
    30301 aggtgttgaa gttacttaaa ggtacaaaaa ctccaaaacc agagcctaaa acatcactaa
    30361 tgcttgctat attaagtatt tgtttgttta taatagcgta ttataatgct attacctcaa
    30421 ccgaccaata tacaacatat ctgcgcttag ttccagttac atcccttact atagtagcaa
    30481 cttacttgtt cttttctcaa tttagtgtat tttttatgaa gaagctaaaa ttaaacaaga
    30541 gattttatag aaaaaataca aatatgcttt ggatttcgaa cttgatttat aaggtaaagg
    30601 ataatgctag aatatttttc ttgataacta taacttctgc agtagcattt actgctatag
    30661 gtacagttta ttccttttgg aaagatgtag agcgtcaaat taatttaata tatcctaaca
    30721 caatatatta ttcaacaatg acattgcata atgaccctaa aaagcctgat agcaaagaaa
    30781 aagacaagga aagaatgatg tttatagaaa ataatctaaa aaaagaggat gtagactata
    30841 caaggactaa tggtgaattt aaaactgtat ttcccaagaa aagtgatttt aatgtcagaa
    30901 ttatgaaaga atctaagtac ttagaaatta cagaaactat aggggttaag cctataagtt
    30961 ttgaagataa tgaatgtata tcattattat catcaagttt accaggaaat aataacgtca
    31021 aagaaaatat tattgtaggg aatagaggtt taaaggtggc aaaacaagtg gaagaatgtg
    31081 ttatgccagc atattacaaa aatatgtatg tggtaaagga taatttttat gatagtatag
    31141 aatcaaaatt tatagtggat agatttaccg catttgaagt agaggattca agtaaaacta
    31201 tagagatatg cagagaattt gaaaataaat ttaataatga gtcagggatg caaccatatt
    31261 tgtttttctc taaagaatta atgataggaa ctgggaaatt aatgtattct acatttatat
    31321 ttttagcaat atttataggt ttaattttct ttgttactac aagtagtttt ttatataata
    31381 aattttatat ggattgccaa gttgataaga aaaagtatga acagttaaat aaattgggta
    31441 tgacatataa tgagattaaa aaagcttcaa caattgagat tggaatagta tttttgtttc
    31501 cttatgtagt ggctgttata cattcaatat ttgcacttac tgcactgaaa aattcttttg
    31561 atatagaagt agcatcatca gctgttttgg taatgggaag cttgttcttg gttcaaatag
    31621 tttatttttt aattgtaaga aataattatt taaaagagat aaggttaaat ttagtcaatt
    31681 tttagttact attattaaat gataataaaa agggtttaaa attaattaat attactggaa
    31741 ttatagatgt ttattttttc agtaatattt tttattgtat taactattaa aattttgtac
    31801 aaatataaaa tataatatgg taaatgtcaa aattataaaa aaattctact tatataaaat
    31861 ataaagaggt tatatgtaca tatgtgtaga aataaataat aaaaatatca attaatgtta
    31921 ttaggggggg ttactcatta gtaaattagc taatacactt agaatgatga tattaattca
    31981 aagcagaggc aaaatgaaat gcaaagaatt atcagaagag ttggaagtaa gtgaaaggca
    32041 aataaaaagt tacaagatgt atttagagca agcaggtata tttataaatt caacacctgg
    32101 gatttatggt ggttatgaaa tagataaatg taatagcata tcattaatta aattattaga
    32161 tagtgaagtt tcaattctag atatgataaa ttcacagtta gagtataata atgatattta
    32221 caaaaatgaa tttaataata ttgtagaaaa aataaaagca gtattaaata caggagaaaa
    32281 aagcgataca tatatggatt attttacagt tcaagcacaa cgtaattgtg attatgagtc
    32341 tgaaaaaaat aagtgtaatg aaataattag agcatatacc acaaaacaca aattttggat
    32401 agaatattat tcattaaatt caggaaatag tgaaagaatt gttcatccat atggtttatt
    32461 taattataaa tcagatactt atatggtagc tttttgtgaa aaaagattta agtttataga
    32521 ctttaaatta tgtaggatta aagattataa ggttttagaa gaaaaatata atgtagataa
    32581 aagttttagt tgggatgaat atagtaaaaa tagtatagga atttataagg gagaagaaat
    32641 taatgttgtt ataaaaatta gtcatccatt ttcaacaatt ataaaggaga aagtttgggt
    32701 taataatcaa caaatcatag aatatgatga taaatctata atgtttaaag ctaaaatgag
    32761 aggttatgag gagataaaaa gttggatttt aagtatggga gcttatgttg aggttgtaga
    32821 accagataga cttagaaatg atatattgtc agagattgaa aaaatgaaaa aaatttactg
    32881 attttttcaa ataatttata cttggaccaa tatacttcac ggtctagtgt taatatatta
    32941 attgagagag gtgatattat gaaaatgaaa attgaattta gtacaggttg tataccaata
    33001 tcttataatt cgctctttat gagtattata aaagaagcaa taagaaaatc taatgaagat
    33061 tactataaaa acatgtacta ttataaagaa aagaataata aaaaaactaa aaattttaca
    33121 ttttcggttt atataaaaaa gtatagtatt gaaggtgaca attttattat agaagataaa
    33181 gtaatattaa atataagtac tccagattta gaattgggtt ttcatatata caatgggtta
    33241 atgacttcta aaaaatgttt atataaagcc tatgaactta caagaattag aatcgattta
    33301 tcaagagaaa agaaggtaac agaagaaagg gtactattta atgcattgtc tccaatctgt
    33361 gtaaagtcta aagaaggaaa attcttggag ataactgatg atagatacat agaagaacta
    33421 aactatataa ctaatgaagt ggttaaaaat tataggggga atggattaaa aagaaagtta
    33481 gaatttgaaa atataggtct caaaaaggta gtagttaaag agagtttaag agaatttaaa
    33541 aaaataacag gtaaagagta tcaatatatt aatggttaca aaggtaaatt tatattgaaa
    33601 ggtgatattg atgatttaaa tcttatctac aatctaggaa ttggttttag acgtgctcag
    33661 ggatttggag atgtagatat tttagaatgg aggtgagata aatgaagtta agagtttata
    33721 gaggagattg gttttttaat atgggtatag ttggattttt aaatataata aagaaagcag
    33781 ataaacaagc tgaaatattt attatggaag attatatcga atttgatagc ttatttcttg
    33841 aaaactttca tgagtattat tttaattact ttatggatga atatgatgta tcaaaaagaa
    33901 ttaaaaaaaa tattgattat agtataaatt ttattaaatc taagcctgat agaatcaaag
    33961 atggaattaa gaaaattaaa gatagtgtga aacaacaaaa tgataagatt aaaaaatttg
    34021 atgaagaaaa atttaacctg ataaaagaga agctagatag tatgtctaag ataaaaagtt
    34081 atgatgaatt tgatagttta gaatctttag tagatgagac tatagatata tttaaaataa
    34141 aatcaataaa tgacaggctt acagcaaatc tttataaata tgtagttcaa gataattatt
    34201 ttggacaagt tagttttttt aatgttgcta aggcgaaatt agatttagat ggattaaaac
    34261 aggtaatgtt taatgattat ttaagacaaa ttatatattt tggagagtta gaagatttat
    34321 tagaagagaa tgactatgat aagttgaaaa actatttaaa tgatagatta aatagtatag
    34381 ctaaggatat aaatgaaaaa aaagttagta agtctagtat aaatactata gaaaaaatta
    34441 tgaaggaaat aaataaaaac tttataaaga aaaataaaag catagaagat ataaaagagt
    34501 atatggatag tttagaagta tgtgaaatgt gtggtttata taagggaata ttagatgaat
    34561 actcagaaag taattttgct ccacttggag taagcaccaa taatgctagg aatatgtttt
    34621 ggaatcagga gtatgtatca tcaatatgtg atgtttgtaa gctaatattg ttctgtactc
    34681 cagcaggggc tacttataca agaaagaatt atttaattaa tgaagaaaat gagttttatt
    34741 tatttgttaa catggatact tctataaatg agctttttga aagaaataat agtttaaaag
    34801 ctcaaaaaag tgagtcttca gattccaaag atgaaaatcc ttttaatcag cttataaaaa
    34861 gtatagtaga agaaaataca ttaaaaagtg aatggcaact tcgtaatata ctttttgtgg
    34921 aatttaaagc aagtatagat tctaaaaaat gtaaaataaa ttattttaat attccaactt
    34981 atttagcaaa attttttaca gacaagtatg caaataaaaa aatacaaagt atctatgatt
    35041 acaagcttaa atcaaatgta ctagatttac tcttgaaaaa tagggacttg aagcatctaa
    35101 ctaataacat tttaagaaat aaagttaaaa atgatatgga aagcaacaac aaatcaaata
    35161 tatcaggaat agattgtttt agagtagtcc aattaagagt attaataaat agctacaaaa
    35221 agggggtata taaaatggat agtaaaaatt tggagaagaa tgatgaaaag ctgaaaataa
    35281 tttattattt aggttgtgat atacatgact attttgttaa taaaaattct aaaaataaaa
    35341 tagatggagt aagctataaa cttttaaatt cagttaaagt cggaaataaa agtgatttta
    35401 tggatacaat tataagagtt tttatgtcag ctgaaaaaca gattccagca tttattttag
    35461 atatagaaat tgaaaaagat ttagactttg aatctatagg tcatgctttt atatctggat
    35521 taatttctgg aaaatatgaa ggaaaagata aactaccaaa cgaaaaggag gaaaaataag
    35581 atgaaaagag gattaacatt tacagtaata gcacaggctc aaagtttaaa ctatggtgaa
    35641 gggataggca atatatcaga attaaaaaaa ttaagtagag ctgatggaaa tatgtataca
    35701 tttgcatctc gccagtgttt aagatatgac atagtacgat tagcagcaga attgtttaat
    35761 tggaatttac aggttgtcga taaagaaaaa ggtactattc aatttaaaga taatataagt
    35821 ataagagaat cagaagaaat ggatttattt ggatatatga aaacaaataa aaaagatgag
    35881 aaagataaaa aaggaggttc tttgactaga gaagctactg taagattaag taatgcgatt
    35941 tctcttgagc catatagaag tgatatggat tttttaaata ataaaggatt tgcagataga
    36001 ataggagaac accctaatct tgccaacata gagcaacatt taagttacta tacatatacg
    36061 gttactatag atttatctaa aataggtaag gatggagata tagaacttga taataaagag
    36121 aaatgtagaa gagtagtaga atttttagaa ataataaaag tattgaatag aaatattaga
    36181 ggtagacaag aaaacttatc tcctctattt gtagtaggag gagtatatga aatagcaaat
    36241 ccatttttct tgggtagaat taaattaaaa ggagataaaa atggatttaa aataaataag
    36301 caagctatag aagaagtaat tcaaggtact tttttaggaa aagatttaaa agaatttacc
    36361 tatgttggaa tggtagatgg ggtatttata aataaagaag aatttaaggg attgtttgaa
    36421 gataattttt taagtgtaga taaatttttt ggacaactag ttaaagaagt aaaggaatat
    36481 tatggggtga attaatatga aggttttgaa attagattta tttcaagaaa ctgcatgcta
    36541 taaaaaacca tttgctatga agattacaga gacatatcca ctgcctccat attctacaat
    36601 aaatggatta attcacaaag tattaaatgc tacagaatat ataccgttta atataagtgt
    36661 acagggaaca tatgaaagta tatttaataa ttaccagaca acgtattttt ataaaaaaga
    36721 tagtattaca tctatgccaa tgaatagtca tatgctattg aatgtaaatt tgataattca
    36781 tataggtggg gattttgatt tattggaaga aatatatgat agtttattaa attatgacga
    36841 gcatttatca ttaggtagaa aagaagattt agtaagaatt aatgatatta gatttgtaga
    36901 agtcaataaa tttgaagtag atgaggatat acaattagat gattatgaaa attataagtt
    36961 atcagaatgt aatataagaa tgcctatata tataccaaaa acaagtttac aagatacaga
    37021 tatagatggt ataagttata ggctcaataa ttactatgat aataatgctg tggaagataa
    37081 aaaaagggtt tggaataagg tagatagtta ttatgttgag gatggaaata ctatatcaat
    37141 tggagatata ttattagata atgaaggaga tttattatat tttaataata taaattagga
    37201 gggagagtat gttatatgct aaatctaatc cagtggaaac acttagagag catactgatg
    37261 aacttttaaa acaaatgaat gtattaagag aaagttatgg aaaaaatata aatagcttag
    37321 attttctaga agaggagata ttttggcaat tacttgactt tgttatagaa tttcatgata
    37381 ttggaaaggc attttcaccg tttcaagagt taataaaaag cagaatggat actaaaataa
    37441 atgaacctaa aatagtaact catttagaaa ataatgtagg ccataattat ctttctcctg
    37501 catttattga ttatagttat atagacagga aaaaaaataa agaacttaga gcagtattaa
    37561 atcaagttat tgtatatcat catgaaagag atatctttat agataaagat tttaaaaatt
    37621 taatacaaaa aatattagat gaagatttaa taaataaagt ttatgaacta cagcatgaat
    37681 ttaaagttag atatccaata aaaacagaaa gattgagtaa agtatatcta caaagtgtag
    37741 aaaaaagaat agataaaaat cataagtact ataatttata tattatgtta aaaggaatac
    37801 tacatagact agaccatagt gcttctgctc atgaagttgt ggaatgcaat aatgttataa
    37861 atataggaga acagacagaa aattatttaa tgaaagagtt tggtagtttg agagaggctc
    37921 aatcatttgc taaatctaat agaaataaga atataatact gattgcatct acaggaatgg
    37981 gaaaaacaga aactgcctta atttggatag ataaagacaa ggcatttttt acacttccat
    38041 taagagtaag tataaatgca ttatttgata gagcaaaaaa tatagttgga gttggagaat
    38101 caaatgatac attcttaggt ttgttacatt caacagcaat agattatcta gaagaaagta
    38161 atcaagaaaa ttcaagtgag attgtagatt tagcaaagtt attatcttgt aaactgacat
    38221 tttccacaat agaccaaata tttaaatttc cttttttgta tagaggctat gaaaaagtgt
    38281 actcaacatt agcatattca aaagtagtaa tagatgagat acaagcatat tcaccagaaa
    38341 tagcagctgt attggtaaaa ggtatagaaa tgatacataa gataggtggc agatttatga
    38401 taatgacagc tactatgcca accatatata tagatgaatt aaaaaaaaga ggtgtaatga
    38461 atagtaactt agctgacttg acatgtaaca cagaaaaaat aagacactgt gtgtctattg
    38521 tagaaaattc aatagatgaa aacttaggta aaataataca aagtggaatg aataaaaaag
    38581 ttcttgtaat agtaaataca gttaaaagtg ctgtagaaaa atatgagtta atagaagaaa
    38641 tagttaaacc aaaaggaata gatgtcaact taaatctttt acattctatg tatatacaag
    38701 aagatagagc aaaattagaa aaatatataa aagaatttgc agatagtgat agtaatggta
    38761 tttggattac tacacaatta gtggaagcat cccttgatat tgattttgat gagcttcata
    38821 cagaaaattc aacacttgac agtctatttc aacgatttgg tagatgttat agaagtcgtg
    38881 agtatgaaga aaatagccca aatatattta tatatacaga aaaagctaca ggaataggta
    38941 gtatttatga taaggatatt gtagaaaaag gacttgagct actgaaaact tttataaatg
    39001 gaaaagaatg tgtgaagatg aaagaaaaat ataaggtaga aatggttaag atactatact
    39061 ctaaagaaag tctagaaggt acagcttttg aaaagagatt taccagtgct ttaaatattt
    39121 tagatactat aacgccatat agtttaggtt ctaaagatgc acaaaatata cttagaaata
    39181 ttgaaggata tacagtaatt ccagaggata tatataataa aattgaagaa actttaatca
    39241 aagattatga agagttggga caagagctta taaatgcata tagtaatgat gatagacaat
    39301 tgataaataa aataaagtct aagagaaaaa aagcaagaag agagataatt aaaaaaactg
    39361 taaatttacc aatatataaa gctaaacaaa atgtaattga catacaggtg aaaggtcttg
    39421 aagatttaaa aatactttta tataaatatg atatacacga aaataagcac acaaaacaga
    39481 tatttggtaa aggtgtgctt ataagtaatg aaatagacca atttatttga tttttatatt
    39541 aacaatgtgg ctaaaattta ctaaagaagg tgattttgtg ccaatagatt tagaagtatt
    39601 aaaagttcaa ggtgtaaaaa taaattatta ttatgtatgt aaaagaaaac tatggctatt
    39661 ttctaaagga ataaccatgg aacaaaatag tagtagagta ttgtctggga agatagtaca
    39721 tgaagattca tataaaagaa tgaaaaataa agaaatattg attgatgata tcttgaagct
    39781 agatataata aaggatgagt atgtaaaaga agtaaaaata agttcaaaga tgaaagaagc
    39841 agatgaaatg cagttatact attacttata ctatttaaag aatagtatgg gtatagagaa
    39901 aaaaggaact ataaattatg ttaaggaaaa gaaacaagaa gaattgatat tgacagaaga
    39961 aaaagaaaga attattgaaa acacacttat aaatataaat gaaataaata tgtagttatc
    40021 tcctcccaaa attgagaaaa aacattattg tacaaaatgt gcttattatg aattttgttt
    40081 tgtgaaggag gagtaacaat gtataaagac tattatatta taagtaatgg ggatataaaa
    40141 aggaaagaaa atacgattta ctattacaat ttagaaggtg agaaaaaaat attaccagta
    40201 gaacaagttg atgatattca tatatatgga gaagtagatt taaacacaaa acttataaat
    40261 tacataagta aatatggggt gatgcttcat ttctacaatt actatggata ttattcaggt
    40321 acatattatc caaggaagaa aaatgtatca ggattcagtt tagtatgtca atcagcctgc
    40381 tatttagata aaaatgaaag attatactta gcaaaatcct ttgtggaaag tgcatcatac
    40441 catattttaa gaaatatgag atattacaaa gttgatgaaa gtttaattga tactataaag
    40501 gatgaactaa atgatttgaa tgatgtcaaa gaaatatcag aacttatggg taaagaaggc
    40561 agaataagaa aaacatacta taaatcattt aatcaaatat taaaagatga ttttgaattt
    40621 tataaaagag aaaaaagacc tcccaaagac ccagtaaatg ctcttatgtc ttttggaaat
    40681 agcataatgt atacgaatgt tttaagtgag atatataaga cacaacttga ccctacaata
    40741 agctttttac atgaaccatc aacaaagaga ttttctttaa gtttagatat tgcagaaatt
    40801 tttaagccaa ttatagttga cacaataatt tttagcctga ttaataataa aagaattaat
    40861 aagaatgatt ttgaatatca agacaaaatt tgttatttaa gtgaaaaagg aaagaagaaa
    40921 tttttgcaag aatttgaaaa taagatgcag acaactataa aacatagaaa tctaaataga
    40981 aaagtttcat atagaatgtt tataaggtta gagtgttata aattaattaa acattttata
    41041 aatgatgaaa ggtacaaagt tttaaaggtg tggtggtaag tatgtttgtt attgttactt
    41101 atgatattgt tgaagcaagg tcgttaaata gaattagaag gatacttaga aaatatttga
    41161 cttggacgca aaattctgtt tttgaaggca atattactga aggaaagtta cataaatgta
    41221 tttctgaaat agaaaatatt attgataata gcgaggattc aatctatgtt tatgagataa
    41281 aaaatcctaa ttcaattaaa aagaaatgtt atgggattga taagtattct gatgaaatgt
    41341 ttatataggt ttgcagtgag cgatatttat gctaaaatag gtgttaacag ttggaatata
    41401 agggattgaa ggtgtatgat aactgttatc aattgcacta ctgctcgctc actgcaaatt
    41461 ttgatgtttt tattgaatta taattgcttg attgaagtat tttcaatgta ttcaattata
    41521 cctattttgg ggttttatat taactaagtg gtatgtaaat gttttcaaaa aaaatggaac
    41581 aatcatacaa aatgattgtt ttatattaac taagtggtat gtaaattcta taattatgcg
    41641 tgatttgatt ggtagaaacc gttttatatt aactaagtgg tatgtaaatg cataaccaaa
    41701 aacttcaaaa tcaagacctc gaatttgttt tatattaact aagtggtatg taaattgcgc
    41761 aataacatgc tgaaaactgc aatttcgaag tgttttatat taactaagtg gtatgtaaat
    41821 ctaaagcaac taaagcatat gatttatcta acaacgtttt atattaacta agtggtatgt
    41881 aaataggata aagaaaagac tcacacaagg cacagtgtca ggttttatat caactaaggg
    41941 tagataagta gaatattagc aatatcaacg agtatttaga aacttatttt atattaataa
    42001 agcagtatat aaaattgtag aatcaacaat agcatatact aaaacatcca ccttatatta
    42061 actaaatcat atctaaataa aatacactta cctataaaca ttataaaatc aatacaaaaa
    42121 tgaggtgaaa taaaatttat gataaagaaa ttaaacaata aagacataaa taaaatcatg
    42181 gaaatatggg aaaaaagtac aatcaaagca catgacttta taagtaaaga atactggcaa
    42241 aataactata atactgttaa aaacgaatat atacctatat cagatacatt tgtatatgat
    42301 gatggagatg aaataaaagg atttataagc ataatagata aaagctttat aggagcttta
    42361 tttataaagc ccaaatacca aaatctaggt atcggaggta aacttttaga ttatgcaact
    42421 aaaaaatata aaagtctaag cttagcagta tataaagata ataaaaaagc agttgtgttt
    42481 tataataaaa aaggttttaa tatagtaaaa gaacaagtaa atgaagattc aggatttaaa
    42541 gagtacataa tggaatatag taaataatat gattacattc tattaaaagg ataattaatt
    42601 tatttgccat ttgatttttt aagagtaatt tttaaaatag actatatgaa gataaagata
    42661 tttattatag atgtaagtta atcagaattg atatagctac aaaagaggaa aataaaattg
    42721 tatggtgtat ttcagattta acaaatttac tatttaaaga taataagttt gatataatat
    42781 taaagatact ttcacctata aactataggg tatttgaaag aattttaaat aattatggaa
    42841 tgctaataaa ggtttgttaa aatttaataa ttattagatt atagaaaatt gccgtgaaat
    42901 tagttcatca agaactagtt tcatagcaat tttaattcgt ataagtgtat ttatttttac
    42961 agatttaaaa aacttataca gtatctaata atgtaatctt attactttag cctataaata
    43021 tttaaatctt aaaatgttct ctttgagata agtttatttc agagtcacaa tttccacaac
    43081 agtaagatgt tgagacatct ttaaattttt cagtattctc atcaaagttc atttttttct
    43141 ttgcaataat tcctacctta gttaaattag aaccacaatt attacagttt tgaattttgc
    43201 ataggttata tagtttatca agtgtaatat cttctaataa ttcatcacaa ttacaacatc
    43261 tgatagaaga aacttcacta cacatttcaa taggttcagc ttctttagaa gaaaatttat
    43321 atgttatgtc atttgatact ttataacctg tatcaaatat attagaatta caacttggac
    43381 ataagtactt tggaagatat atatcttttt tttcaaaagt atcactacta atattacagt
    43441 ttaattcatc taaaattggt ctttcatcta ggttattacc tttatttaag cttagaagat
    43501 aattataaat ttttttatct tcattctgtt ttgatgtatc taacaaatgc tccattatat
    43561 tagtgtattt tttgtttttt gaaggcatgt ttaaatccag ataattgttt tcaatagcaa
    43621 agcatactat attgaaatag ttatatttaa ctgcaaaaaa taataacatt tcatcaaata
    43681 ctttatctat tattttgtca gaaatactta tccaaaaatc tggtgactct aagtaaactt
    43741 tcctactaag ttcatctaac tcttcatcta tattatttat attattttca ttaactttca
    43801 tatcatcact tccttttaaa tatcttgtgt ataaactatt tgttactatt ttttatataa
    43861 aataaaatct tatataaaaa tatatcatat tataatttac aagtatagtc taaatagagc
    43921 tgtttttaag caaagtttta taaatgacta ttaaagtata aagtaacagt ataaagttta
    43981 cttataaatt aaatgtaaac ctaaatactt ataatagttg acaaaaaaac gtctttattt
    44041 tatactaaaa caaagcttta atagaagctt tgtatatgta catataaact aaatgaaata
    44101 agacatatga agggaattat aaaaatgaaa aatactaaag taaatattca agatttaact
    44161 aaaatgtcaa tatgtgtagc attattgtgt atatcatctt acatatatat accattgcca
    44221 tttactccag caggagtaac agcacaaaca ataatgataa atttaatagc tttgatttta
    44281 acaccaagac aagcatttag tacagttggt gtatatataa tgataggttt aattgggatt
    44341 ccagtatttg gtggaggtac atctggtatt ggaaagttgt taagcccaac aggtggtttt
    44401 tattttgggt ttttgtttgc agcactaatt attagtttat taaaaggacg aaacaatgat
    44461 attaagagat atatactaat aacaattttt gttggaatgc ctattatata ttttatggga
    44521 acagtattta tgtgctattt taatcaaatg acagtagaag cagcactttt tgcagcagta
    44581 gtaccatttt taattggaga tacaataaag tcagttattg catctttttt aggcactaaa
    44641 ctgaacaatg tactcagaag aaatctatga taaatctata atataaggaa gggtgtaatg
    44701 tatgaaggaa gtttttatat taggaggatt gagaagtcat ataggtctaa aaaatggaat
    44761 ttttcaattt gttcaacctg aattactagg agcaagtgtt ttaaaagatt taattaaaaa
    44821 gtatgaaatt gacaaaattg atgagattat atgtggaaat gcagttggga caggagggaa
    44881 tatagctaga ttaatgactt taacagcagg agtgtcaaat gaagtacctg cttttactgt
    44941 ggatatgcag tgtgcttctg ctatgatgag tatagacata gctttttcaa aggttaaatc
    45001 tggtcagtgt gatttaatta ttgcaggtgg ttttgaaagt agttctctac aaccaatgcg
    45061 cacatatcat aagaatgata agcgatataa tacaaataat ccaaattata cagttgctca
    45121 attttctcct gatgataata gccaaaatag tatgctcgaa ggtgcggaaa gagtagcaga
    45181 gttatatcaa attgagaaag cagacttgga tttttgggta aaggaaagtc ataaaagagc
    45241 aaaagaagca agagaggaaa aaatacttga agatattata tctcctataa ataatagtac
    45301 ctatgatgaa ggtatacgtg ataagatgag tcaaaggtta ttagatagga tgccatcaat
    45361 tttaggaaaa gaaactatta caaatgcagc aaattcatgt cttattaatg atggagcttc
    45421 atttattata atatgttcta agaagtattt agaacatgta aaaaagaagc ctaaagcaaa
    45481 aattattaac acatgcacga taggaacaga tgcaacctta agtccaacat cagcgataca
    45541 agcaatggat aaacttttag agatagaaag ccttaattat ttagatgtat ctgctgttga
    45601 atttaatgaa gcatttgcag ttatagatgt gttgtttcaa agaaagtatc cagagttaat
    45661 agatagatat aatatatttg gtggagcttt agcgtatgga catccatatg gtgcttcagg
    45721 tgcaattatt gcattacatc ttttaaaagc attagaagag actaagggta gatatggaat
    45781 ttgctctata gctgcagctg gtggtctagg ttcagcttta ctgcttgaaa gggtgtagat
    45841 tatgaactat tatgaacttt taagaataaa aaaagagagg cataaaaata aaaatttttt
    45901 aattatagat ggagaaaaat atacttatga aaatctattg agttatagtg aggaactagg
    45961 aaaacaaatt tctttaggtg aaaatatccc aattttaata tattctaaaa atataatgtt
    46021 tcagttgatt agtttttttg ctattaatta ttcaaaaaat attcctatta tttgtcatta
    46081 taatctttct aaaaaagtat tagatgatat tttattaaaa aataatattt caatcattat
    46141 atctgatgaa tctatggacg ttattgattt atatgatgat aacaataatg aagtagcaaa
    46201 aaaagttaat ttttctattt ttaatcctaa atttaatata tatatgtatc aatataagaa
    46261 gcttataaat tatttagata aaagtatttg tatgggagct ttatcttcag gttctacaag
    46321 tgttccaaag gtattatata gaacatatga gagttgggct ggattttttc ctatacaaaa
    46381 tggtattttt aatatctctg gggaatcaat cttgtttgtt aatggaacac ttagttttac
    46441 agggaatcta aattctataa tgtcagtatt atatgaagga ggtagtattg taataagttc
    46501 aggtcttaat tgtaaatcat ggataaggac aataaaacaa tataatgtaa ctaacatata
    46561 ccttatacct acaaaacttc aacttttggt taaacactta aaagaaccag tactcaaagt
    46621 tgtaagtatt tttacagggt ctcaattatt atttgaagat actgcaagaa atctaaaaaa
    46681 atatatgcca aagtctgaaa ttattttata ctatggggca agtgaattaa attatattac
    46741 atatttatgc tatgatgaac taattgaaaa acctctaagt gtaggcagac catttccagg
    46801 aatagatata tatattagag aaggaaaaat ttttgtgaat acagaatatg cagtatataa
    46861 tgcaaccaaa ccttattctg tcaatgatat tggatattat gataatgatg gatacttaat
    46921 atttgaagga agaagtgatg acattttaaa tattggagga tttaaagtta gttctactaa
    46981 gattgaaaat gaagttaaaa aaattcctca aattgaagat gcaattgtat tgccgtactc
    47041 agacactata agaggaaatc aaattgtatt atttgtaata actatagaca aaattacgaa
    47101 gaaagatttg ttgattaaaa tgaaagataa tctaatgaaa aatgaaatcc caaagaaaat
    47161 tatcttttta aattcatttc catatacctc ttctgaaaag atagatagat tagcattatt
    47221 aaaaatgtta taagtataat atttagtaat tttagtgaac caatgtattg ataaaaacat
    47281 attgtatata gtaaaggagg cttacaatat gtcaaatcaa tacgatataa ctgttattgg
    47341 gggagacctg cgacaagtgt acatggtaaa aaaactaatt aataaagggt attctgtagt
    47401 cacttatggg atatcaaatg aaattataaa tggaatcgtt ggaaaatcaa cttcactagc
    47461 tgaagcacta tccaaaagtt ccattatttt atgtccaatt ccatttacaa agaatcaagt
    47521 taatattgaa aatacggatg attgtcttga tgctactatt gataacttgc taattaattt
    47581 atctcctaat caaatattat ttggaggtaa cataccaact aaagtttgta aattttgcga
    47641 gcaacactct attcagattt atgattttat gaaaatgaat gatgttgcta ttttaaatgc
    47701 agttgctaca gctgaagggg ctatagcaga agctattaaa agaagtataa tcaatataca
    47761 tcaaagtaac tgtttagtat taggttatgg aagatgtgca caaatacttg caaaaaaatt
    47821 atacactttg gatgcaaatg tatgtgttgg cgcaagaaat aatgatgcaa gaagtacggc
    47881 taatgcattt ggatattcca gtatttcttt aagtcaactt gatgaaaaac ttttacaatt
    47941 tgattatatt tttaacacca taccagagtg tattttaacg aaagaaaggt tagaaaaagt
    48001 atcacaagaa gtaactatta tagatatagc ttcttctcct ggaggagtag attattctgt
    48061 tgttaaagaa gcagggatta atgcgactct ttgccttggg cttcctggta aatattcacc
    48121 aaagacatct ggtgaaattc ttgttaacgc tatagaaaat attataaatg aaagaaggga
    48181 ttagaaatga gacttgaagg acttacaatt ggagtaggat ttactggttc gttttgtact
    48241 tatgataaaa tatttataga gttagagaat ttggttaaag aaggagctaa tgtacacact
    48301 atattttcag atgtatcaca aaatatcgat tgtagatttg gaaattctga agagtttatg
    48361 aaaaaagcat atgaacttac aggaaataaa cctatagtta cgattgaaga ggcagagcca
    48421 tttggaccta aaggaattgc tgatattata ataatagctc cttgtactgg aaatactgct
    48481 gcaaaattag caaatggtat tacagattca ccagtattaa tggcagcaaa aggtcatctt
    48541 cgtaatgata aaccactagt aatatcaata tcaacgaatg atgctctaag ctttaatttc
    48601 aaaaatattg gcattctcct taattctaaa aatatatatt ttgtaccttt tggtcaagat
    48661 aattgcaaag caaagcctaa ttctatgatt gcacatactg agctaataat tccaactata
    48721 gaacttgctc tagagaacaa acagctacag cctgttataa aaagtccaca tcaatagaat
    48781 tggttcttat aatattatgt attagataca atactagcaa agaggctgtc tcaaaataga
    48841 gagaagcctc tttttcttgt tgaaatgatg aaaatatatt taatttcata caaaaaaatg
    48901 cctcatggac taaaaagtct attttgagct aatctccgta atttttggta tattaaaatt
    48961 atttacttaa tccaattttt aaattagaat ttatatcgtt ttgactcttc aaatatcaat
    49021 ctaactgttg ttgatacaaa agaagaggac ataattaaaa caaataccga tagtcctcta
    49081 ataaacaaat tatctacata ataagttact attccaatac ctccaatcgt taaaattaca
    49141 cttataatca aagaaaaaat gctaattgtt tttaattttt tcatgcttat cctccttctt
    49201 ataaacttca aatttatcta tataatatta aatatatttt atttcatagt atataaaaat
    49261 catgaatata tattttttta attatactat atgttgtaaa tgtttgtaca tttaactata
    49321 tttactttaa cttgttaatt aagtttttat tttcattttc aagtattttt atttttaaac
    49381 ttgatagagt atcatattaa aaattctttt tataaag
//
LOCUS       DAMJXI010000024        48812 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.025, whole genome shotgun sequence.
ACCESSION   DAMJXI010000024 DAMJXI010000000
VERSION     DAMJXI010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48812
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.025"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            115..1332
                     /locus_tag="PC465_001791"
     CDS             115..1332
                     /locus_tag="PC465_001791"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HDF2649090.1"
                     /translation="MMNVTLTDVKEARETIKNIVKRTDLLESVKLSEKTGANVFYKCE
                     NLQKTGSFKLRGACNKIASLTDEEKANGVIASSAGNHAQGVALGAKMTGIKSTIVMPA
                     TAPLAKVSATKGYGAEVVLNGAVYDDAYAKAVEIQKETGATFLHPFNDKYVIAGQGTI
                     SLEIFEQLDNKVDTILCPVGGGGIISGVAVAAKALNPNVKIVGVQTANIPSMKESIKN
                     GKVTTAFNDTTIADGIAVKTPGDLTFEIINELVDEIVVVEETEIAESILFMMESQKIV
                     SEGAGAVCTAAILSGKYVPAKDENVVCIISGGNIDINTLYRIIGVALAKEGRRYSFST
                     IMEDKPGNFAELTRIISENGGNILSANQGKLSAGEALGKQSAEFILETIDYDHIARIK
                     KAIEEKGFKIIEL"
     gene            1427..1807
                     /locus_tag="PC465_001792"
     CDS             1427..1807
                     /locus_tag="PC465_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDF2649091.1"
                     /translation="MKHEVIHTNDAPAALGPYSQAIKAGNLLFVSGQVPLVPETMEVV
                     EGDVQAQTAQSLKNLKAILAESGADFSNVVKTTVFIKDMNEFGAINEVYAEYFGENKP
                     ARACVEVARLPKDVKVEIEVIAVL"
     gene            2091..2573
                     /locus_tag="PC465_001793"
     CDS             2091..2573
                     /locus_tag="PC465_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2649092.1"
                     /translation="MLNFFKKNKSYKLHAVVSGNSINIEKVNDSVFSKKLMGDGVAII
                     PNSDVVVAPCNGKVTVLTESKHAFGMVSDEGVEILVHIGIDTVSLQGEGFKNEVSQGD
                     TVKKGSPIISFEREKINSQGIDCTTIIIVLNHSEFSEINCMVENEVVAGQDTVIEIMK
                     "
     gene            2594..3409
                     /locus_tag="PC465_001794"
     CDS             2594..3409
                     /locus_tag="PC465_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2649093.1"
                     /translation="MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKVNEDKI
                     EKIYYVQDHMQTKFLELLKNVSPEVMDASQQIISLIPGNEGKFNNKGILSLVEHISFA
                     IDRMKNNVFLPNLMLLDIKMMYSKEFELGVKALEIIYRVCHIHLPEDEAGYIALHFVN
                     LQSNDNLAYDTLKFVKGSIDLIKECYGLELDESSLSTLRFRTHLKFLAQRIFKNEICQ
                     DDKMIEMYDYLINNHPKNKEYLEKLNVYIEKEFRYKLDKPEKIYLLLHLTKIL"
     gene            3462..5012
                     /locus_tag="PC465_001795"
     CDS             3462..5012
                     /locus_tag="PC465_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2649094.1"
                     /translation="MKEKLLGGLETFAKAMVQPLMYLSSAGILMVVGVLLTNDMLLGV
                     LPFFKWEPIQIFGSLIYNCIMAIINNLAVIFAIGIPAALAKKEKHKAALIGFMSYIIY
                     LTASNTMLTSLGQLAKESKMLGLIGTGQATILGIQVVDTSVFGGIILGCIAGYVFNRT
                     SNKTFKGALQIYSGANFSFICMFFVSILIGVVSNFIWPLAQQGIASLANVIKDTGTFG
                     LFLYGFLERILVPTGLHHLIYTPFQFSDLGGVLKVGADTVSGAYAIVMTEMNLPVERF
                     SDSIYYMATGFTKMFGYIGIGAAFIYTAYKQNKKKVKATIIPLIITAVLASVTEPLDF
                     MFVFCAPLLFFVHAVIAGLFIALLKIFDVTALCGGNLLVSIIMNTTVGVEKTHWPVMM
                     ILGLAQIIVYFVVFSFLIKKFNYKTPGREDESTATGEEQSKQLNLDAGIENIIDGLGG
                     KENINTVENCITRLRVNVKDESKINEDIINLTPNSGIVRKGKDIQIIFGLHVHEVRRA
                     VEDFLEAY"
     gene            5109..6461
                     /locus_tag="PC465_001796"
     CDS             5109..6461
                     /locus_tag="PC465_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF2649095.1"
                     /translation="MIITIVGGGSTFTPGIVKSIALREKELELEEIRLFDIDKKRQDK
                     VAVVVNWILKEDVKTDVKLTVTNCEKEAYTDATFIFAQMRVGKYEMREQDEKIPLKYG
                     CVGQETCGCGGMAYGLRTIQPMIKVIDDVEKYAKKDYWILNYSNPAAIVSEACRKLRP
                     NVRIINICDMPIAIIDMIAGSLNINDVHNIRYDYFGLNHFGWFTSIDYKHRDLMEEIK
                     EYIKENKILLPKSYIENLNKSRSTGNRHAVSSWIHVWESVYTMLESFPKYLPNTYLTY
                     YLLSKETVEHSNINRTRANEVMESREKDLFEGVRHYLETGEISEKAFYAGLHGDWISD
                     LAVSIKNDTRSRFLVITENRGAIPNMPYDAMVEIPAYIGKDGPEVIARGPIPLFQQGL
                     MMQQLNSEKLIVEAYIENSYEKALQAFTLNKTIPSMNVAKEILDEMIEVNKEYWPELR
                     "
     gene            6592..7350
                     /locus_tag="PC465_001797"
     CDS             6592..7350
                     /locus_tag="PC465_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2649096.1"
                     /translation="MNIINKIFWQEDRIGMITNNLEADTHSHCMLQLFLGIEDSIEIT
                     VNEKLVKCNCIIVDKNISHSFSARKKVYYSAIIEPTSIYAEQLTSKMNDFGYWICDNN
                     GLEKLRQQGTFLIDNSSKEQYLRFMEMLNNYLNIPITLKHYDDRITELLNLLRTCNCD
                     NHTISSFADKVSLSASRLSHLFKEQIGIPLKSYILFHQMECAFRELLSGKNVTEASMT
                     AGFDTPSHFAGTVKRMMGMPVSLSLKDSEFLKVY"
     gene            7397..8116
                     /locus_tag="PC465_001798"
     CDS             7397..8116
                     /locus_tag="PC465_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HDF2649097.1"
                     /translation="MNKEYLEETKMLNYNEPQLKLLVSSKNWLELDDFHKIKSIYEFV
                     QNDILFGYNASDMLSATQVLNDGMGQCNTKATLLMALLRAVNIPCRLHAFDVTKDFQR
                     GATSKLISLLAPKYILHTWVEVFYQDRWIALEGVITDKKYLEAIQKKFFNHGGTFKKY
                     AIATNDLKNTSIDWDGKDTFIQKEAIVYDYGIFPSPDVFFSTHSQHMSKLKNFIYVHL
                     IRKIMTKNVCKARNNYIDKNE"
     gene            complement(8240..9640)
                     /locus_tag="PC465_001799"
     CDS             complement(8240..9640)
                     /locus_tag="PC465_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HDF2649098.1"
                     /translation="METQSNNKKGNLIIAIVMTGAFISSLSQTLLSTALPNIMSDFKI
                     TADVGQWLTTIYLLIAGIIVPTTAYLINRFSTRKLFITSMSIFSIGCIIALFSNNFST
                     MLIARVLQAMGSGSLMPLLQVIILYLCPEEKRGAAMSLVGITVGFAPAIGPTLSGWLV
                     DSFGWHSLFLFLSPIAILDVILSFILLRNVGETQKLKLDIPSIVLSSLGFGGLLIGFT
                     NQGNYGWTNIATYLPILIGIMSLILFTLRQLKSKEPFLELRVFKNKPFLISTILIMIV
                     YASMMSATLMIPLYVQSVRGFSALSSGSLMLPGAILMVVLNPIAGRHLDKYGPHALSI
                     LGTGCLFLGTLSFAFLGRDTSLIHVSLMYCIRMIGISMVLMPLTTWGIKTLDRELISH
                     ATAINNTLRQISGAIGSAILITIMTSATKKAHMSSNMLSNIHGIDVAFSIAATLAFTG
                     LIVSICFIKRHQIIRS"
     gene            complement(9644..10552)
                     /locus_tag="PC465_001800"
     CDS             complement(9644..10552)
                     /locus_tag="PC465_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2649099.1"
                     /translation="MKGDNKVTEKQRLIITIAQKIFDQKGFQNTSISDVVKECKMSKA
                     TFYKHFETKESFICEIINYYDEKFLEIIHSINENNDIPSSEKLNRKIIAVWKNIFSRT
                     TINTYIRENFSEEQRKATSKLQTKSRANLLNEYKLSLFDNYGDKIEKIIFDLVFLLDA
                     LIHQFIYIIHVQKREINVYFIAKFTIQILDLVVENMDNLNPLIEKSMFLHKQEDEVYF
                     SLHNKSLFFKTIQDIEELIKTDTSLLENPKLLEAIKKLYVEGKNQQYDSLIMDAMIAY
                     LEKEDTLRPKVLLLNSIKNQLKKETL"
     gene            10813..11460
                     /locus_tag="PC465_001801"
     CDS             10813..11460
                     /locus_tag="PC465_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2649100.1"
                     /translation="MKKKICVAIIFALFIVFVEMFIDSSSEGSKIMTAELSKYRKGVN
                     VLSINNIIVANKKYSLPKDYSPQESSEARDAFYKMNKDAQKSGLNLKAFSTYRSYEYQ
                     DRLFKSYVKEHGEKEANRFSAKPGESEHQTGLAFDIGGDDQSCWANKKFNNTKEAKWL
                     YENAYKYGFILRYPEGKENITGYMYESWHYRYVGTEHSKNFAMNNLTLEEYLHIN"
     gene            11785..14424
                     /locus_tag="PC465_001802"
     CDS             11785..14424
                     /locus_tag="PC465_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDF2649101.1"
                     /translation="MSYKSTYQEVIKNLDSSLSGLSKERAEELLEKNGANELKEADKV
                     PTYKLFLESFKDPLVIILLIAALVQIFLGETVESIIIFAVIIINSVLGVVQTKKAESS
                     LESLKNLSAPNAKVIRDNKKMTIPAKNLVVGDIVFLEAGDYIPADGRLIEAQSLKVVE
                     GMLTGESEPVLKHTEKISEDVSLGDQKNMVFSGAVVVYGRGSFVVTGTGMDTEMGKIA
                     GLLESAENKLTPLQQKIEDFSKKLGVGIVILALLIFIIQVARNYFMAGNGEMTQIILD
                     SFMFSVAVAVAAIPEALSSIVTIVLAVGTNSMAKKQAIIRKLPAVETLGSTSVICTDK
                     TGTLTQNKMTVVDYYMYGTNNDELDKEKVNYSYHAKLLTMVSTLCNDSHITSDGKEVG
                     DPTEVALINYSSKNDLDYDKLRSKYIRINEIPFDSDRKLMSTVNSIYGDYIMFTKGAP
                     DIVFSRCKYALKNGSKVDITDEIIEEYKHKNEEFSNRALRVLAFAIKDVPEEDFIPSI
                     DDEHDMTLVGIMAMIDPPREEVMDAVKEAKSAGIKTVMITGDHKTTAAAIAKEIGIME
                     EGDLALTGKELDALSEEQLYEKLENISVYARVSPENKIRIVKAWQHKNNITAMTGDGV
                     NDAPALKQADIGIGMGSGTDVAKDASAMVLVDDNFASIVNAVEVGRTVYSNIIKSITY
                     LFAGNLGAIVSIVFAVFAGWSNPFTALQLLFINLVNDSLPAIALGFEKSEKNIMNKPP
                     RHPDESILAGGTLKAVAIRGCIIGVVTIIAQYIGLQVSPELGVAMAFSTLILARIMQT
                     LPARSNNQTVIKLGFFSNKYVIGAVLVCLGLYSLTLIPVLRGIFSIPTTFGLYQLGIC
                     LGLALISSILMELNKLINRSEVK"
     gene            complement(14482..15585)
                     /locus_tag="PC465_001803"
     CDS             complement(14482..15585)
                     /locus_tag="PC465_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate aminotransferase family
                     protein"
                     /protein_id="HDF2649102.1"
                     /translation="MKLKINKAIEMQLKKSYAIESGHSEDVFEIDCGEGINTVSYSNK
                     AVEAFNALKFDMIRGYPHSIALKDNIVDYWKDFIALDTDRICLADGSIHVIYLLNRLF
                     IEKGDKVLGYSPQFSEYETDIKMHGATYDYVLLKKEDNFKFNEKEFIEKINPEYKVIY
                     IDNPNNPTGQIIPLSSIENIVKEAAKYDIAVMVDEAYGEYMPKENSAVKLLNNYDNVI
                     ALKTFSKGFGLAGLRAGYAVLPEQLVSPIKKISTPYEVSEISRSIAANLLDDVQFIEE
                     LKEKTKDIKNQLLIPWKNLNIAETSDTVSIMTVEHKNKDIDLQQEFAKLKIRVISGSD
                     FTGLDKNFIRFRMPEEKELPEVIKAFQIIDNIE"
     gene            15945..16766
                     /locus_tag="PC465_001804"
     CDS             15945..16766
                     /locus_tag="PC465_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2649103.1"
                     /translation="MGYKLIVTDMDGTLLGNNHKVTDENKTALQKVIKSGINVTLATG
                     RAFDSAKCNVDFLKEDMPIIACNGSLIREQNGNIIYSNKIDTRTCLNILDVLDKYDIY
                     YQCNSIDSMLSKKIEGREDRLSVFLGSETEVIVKDDLREEIFKKDILKFVIIEEKNPS
                     ILDEIRKELRKVQGIKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDN
                     YNDIEMIKFAGLGVAMGNAEELIKQEADYVTDTNQDSGVAKAIYKFLELKESLSS"
     misc_binding    16845..17056
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17143..18459
                     /gene="argH"
                     /locus_tag="PC465_001805"
     CDS             17143..18459
                     /gene="argH"
                     /locus_tag="PC465_001805"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HDF2649104.1"
                     /translation="MKLWGGRFRKAENQLMEEFNKSFGYDCVLYKKDIEGSVAHVHMQ
                     VKCGLLTEEEGKSITEGLKGILEDVENGKLVLDGEYEDIHSFTEINLIQRIGDVGKKL
                     HTARSRNDQVAVDMRLYAKEKANDLVDLISEFKATIKDVADKNPVMMPGYTHLQRAQV
                     VTFKHHLMAYYSMFDRDEKRIKNAIEILDESPLGCGALAGTTHDIDRSITCEQLGFKK
                     VVDNFMDGVSDRDYLLELMSDFSIIMMHLSRLSEELILWSSQEFGFVEIDDLYTTGSS
                     IMPQKKNPDGAELIRGKTGRVYGNLFGLFTVMKGIPLAYNKDMQEDKEGFFDSVHTLE
                     MCIQIMDRMIATLKVNEDKMKQAVKNGFLNATEVADYLVKNNVAFRDAHGIVGSIVIY
                     CEDNKKAIEDLTLEELHKFSDAFKEDIYDFIDYESILNKGIKKNLK"
     gene            18708..19046
                     /locus_tag="PC465_001806"
     CDS             18708..19046
                     /locus_tag="PC465_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HDF2649105.1"
                     /translation="MNLLVIGGHERMEKDYMVMAKKKGYKTKVYTTMSSKLNNSIGRP
                     DAVVILTSTVSHKMSRTVESQAKKQDILIVRHKNSSKVAFNECLDMVDECLGNCSKCK
                     LKDKQKQKNI"
     gene            complement(19173..20462)
                     /locus_tag="PC465_001807"
     CDS             complement(19173..20462)
                     /locus_tag="PC465_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF2649106.1"
                     /translation="MKRNLSLLLICLLIFTSFLGSSNISFADNEPAIVAKHAVLMDYE
                     SGKILYNKDGNSKLYPASTTKVWTACLVLKEVKDLNQVIEIKDLPQIDGSSMYLKNGE
                     SFTVKQLLDALLVHSANDAAFVLARYVGGGNVQKFIDLMNSEAKKIGATNTHFNNPHG
                     LPDPNHYTTAHDMALIAREAMNNDTFRQIVKTKSLKFEATKAYPYERYFVNTNKFLTS
                     HDKITYKGQPINIKYDIVDGIKTGYTDAAGKCLLSSAVKDGRRVIVAVFNSTNADLYL
                     DSRILIDYGFDNFKCATIVDKEKYTDTKKVLFTKQHELIYEPKNSYRIFLEKDESQGN
                     YDTKTELNKIDLPIKKGAKVGTLNVYNNGKLENSIDLIAKNNLDSSLPFLTENNVLMT
                     FVKIIAGILVLLVLFIIASNIKKKKRKKARSKKNMKK"
     gene            20542..21246
                     /locus_tag="PC465_001808"
     CDS             20542..21246
                     /locus_tag="PC465_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComEA"
                     /protein_id="HDF2649107.1"
                     /translation="MKKKVKFISFFVLFILIISSIIVYKSLIFKDDIYVVSKKNLPNE
                     KTHVVENEIKGEDNNHNKVTKDIDKNFQNNKITIYISGAVNRPGIVTIESDKRLYDAV
                     ELLGGTTKEADLNGVNLSVRLEDEQHYIIPKIGEATSVTSNDDSNKPNQKNESRGEPK
                     NKSNKNISNESKVNINVATIEELDSLPGVGEATANKILQHREENGQFSSIEEIKNVNG
                     IGDKKYENIKDLICVD"
     gene            21338..22384
                     /gene="selD"
                     /locus_tag="PC465_001809"
     CDS             21338..22384
                     /gene="selD"
                     /locus_tag="PC465_001809"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:21386..21388,aa:Sec)
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HDF2649108.1"
                     /translation="MKKEQKKLTEMTTAGGUAAKIGPEVLASVLSQLPKNDNIENLLV
                     GLDTADDAAVYKLNDDMALIQTLDFFTPMVDDPYVFGQIAASNSLSDVYAMGGKPLVA
                     MNIVCFPSCHDMDVLAEILKGGFDKVKESGALLVGGHTVDDKEPKYGLSVSGIVSPNK
                     VLSNATAKPGDKLIITKPIGVGVLNTAMKEGMVEQHIADKVIEIMIHLNKYAAMSFEK
                     FDVNSVTDITGFGLLGHTLEMAKASEVSIEIESKHVPIIEGAIEMAQMGIIPAGMYKN
                     MHYVSKDVEVVGNIEVAVQDILYDPQTSGGLLISVKEELAEELVKDMKLNGAIEAKII
                     GSVVPKGEKYITVL"
     gene            22402..23814
                     /locus_tag="PC465_001810"
     CDS             22402..23814
                     /locus_tag="PC465_001810"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HDF2649109.1"
                     /translation="MIVLSKRELFAMLPSVDEVLSDNRIVEIINEYPRSLVLESVREV
                     IDLKRQFILRLKEDASNSVTIEFGEIIESAIERVKLNYSLSLKKVINATGTVIHTNLG
                     RSLLSEDIKDELWCAASRYSNLEYDLDNGERGSRYSHLTSTIKRLTGAEDVLVVNNNA
                     AAVLLVLSTMAKGGEAIVSRGELVEVGGSFRIPSIMALSGAELVEVGSTNKTHLKDYK
                     EAITEDTNVLMKVHTSNYRIMGFTESVSIEELVNLGKKYKLPVIEDLGSGVFIDLSKY
                     GLSYEPTVLDSIRQGADVVTFSGDKMLGGPQAGIIVGKKEYIEKMKKNQLTRALRVDK
                     LTICALEATLRMYLDETKAIENIPTLKMLTYKIEELEVKANKLFEKITALNLNANINI
                     EDGFSQVGGGSMPLETISTKVISITPEHMNVSSLEKKLRLSEAHIIARVYDNKYVLDV
                     RTIFDDEFDVIVEELRKAFN"
     gene            23928..25811
                     /gene="selB"
                     /locus_tag="PC465_001811"
     CDS             23928..25811
                     /gene="selB"
                     /locus_tag="PC465_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HDF2649110.1"
                     /translation="MKNVVIGTAGHIDHGKTTLIKALTGRETDTLDEEKKRGISINLG
                     FTYFDLPNNRRAGIVDVPGHEKFIKNMLAGASGIDIVLLVVAADEGVMPQTVEHLDIL
                     SFLNIKNGIVVLTKSDTVDDEFRELVKEDICEKIKGTFLEDAEIIEVDSISKRGIDTL
                     IEKIDKMSDDIEDKNENSPARLNIDRVFSIKGFGTVITGTLIEGKISIEDDLVIYPQV
                     LKTKIRSIQVHGENKDTAYAGQRTAINISNVKVDDIKRGDVLAAPNSLEESMMLDVKL
                     SLVNHLDKGLKHWDRLRLYHGTREILCRAVPLDKELIESGESGYVQLRLEESIVSKKG
                     DTFVVRRYSPMETIGGGVIIDPSPKKHKKFDEKVIEALKIKEKGELKDIIEEYLKRNL
                     KNYPNIKEIMSYSGAHEEDVKRALETLISEDKVFIIGNMYMHINQYNKLKENTIKLLS
                     EYHKKYRLRKGILKEEVRSKIESNFKTREMDILLEKLSTENAIKIENNIVSLLDFEVI
                     LNDKQKEIAKKIEKRLKSCGVSSILTIDEVSEGNHNYAEVLESMIGNKVEKLDDLYIM
                     DKDIYENAKNILINYIKENKEITLGEYRDLIDSSRKNCMIILENFDRNKITKRVENKR
                     ILF"
     gene            25916..28654
                     /locus_tag="PC465_001812"
     CDS             25916..28654
                     /locus_tag="PC465_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation-associated two-component system
                     sensor histidine kinase"
                     /protein_id="HDF2649111.1"
                     /translation="MKNIIPDVKPDIKEREDMSLLFIIMGSVLLLFIIKDIEKYETLL
                     HAIYTIFLVATGVIIFNTTKFKVDSFSTFLGLIFIATGVLECIYLFNSLGIKTKSIME
                     INITISAITDLFPILGVYLSFKFVKDNKQIYSSVILFIATATLTITSLFIISGICDYL
                     GNGKSQYALGVIISIFIIIISIVSGIELNSSSNKGKWEYDEKKIFNRIIVIIILSRVP
                     NLLHIVIDNRNVERILSQIIINVALYYLYNYIVSKNIKKTALELHDTNEELTKKTESL
                     KEKNKKLIYETEKIEELKGILMKRESRLQSTLDVAVNSIVVFSKDGEITYANKSFRNT
                     FGDYKEQDKLTDKIKNFNDLIESIHYVFVHEKNAEKLISTSDNKVYQAIFAPLIIASQ
                     TEGVLCVLEDKTKKKEYERKLIEANKRSKDFLESIGDGIVVLEGNNKIYVNNACREIF
                     KNNLESIDFSLVCKSEESIEKRYVIDGEVKYVEMSFSQYTNAGTNKTIIVIRDTTSRK
                     ISQIKLEESQSSYSRFIDILPDGICLLKEDLSINYANKSFLDMLAFTNIDDIKDSNIK
                     LLMNANTEEKMKFTDNMAKVLNENRSILLLEYELINSYDDIVEVELSALPFAIYNTRY
                     IMLIIKDLVHKKYSEQAEKELLERFKTDKIKTEFFANMSHELKTPLNVISSSNQLVDS
                     FYRNEKIKDYNNNIKSHVDLVRQSSYRLQRLINNIIDLTKMESGFYTLKLAKYNIVSV
                     IEDLFMNIEEYALRKDIKILFDTDLEEINVYIDKVEIERIMLNLLSNCIKFTDNGGWI
                     YVSIHYKIDKVIISVKDTGVGIPQDKLELIFEEFSQVDKTLSRNTEGSGIGLAIVKNL
                     VSLHGGDIEVVSEVNKGTEFLISLPMKGFSSEHYTEDKRIYNIQEKIKIEFSDIYY"
     gene            complement(28773..29717)
                     /gene="manA"
                     /locus_tag="PC465_001813"
     CDS             complement(28773..29717)
                     /gene="manA"
                     /locus_tag="PC465_001813"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HDF2649112.1"
                     /translation="MEPLFLKPIFMDRIWGGTALKDKFNYEIDSPTTGECWAISSHKN
                     GDCLIENGKYKGKKLSELWNKNRELFGNTPGDKFPLLTKILDANDNLSVQVHPNDEYA
                     KKNENGELGKTECWYVIDCSDDAEIIIGHNAKSHKEFVNMVNNNEWDKLLRKVNIKKG
                     DFFYVPSGTIHAICKGTLILETQQNSDTTYRVYDYDRTDNSGNKRELHVQKSIDVTNV
                     PHINFDTDYKIVSTSDFKCTTFVSNEFFSVYKLDVFGKCNFTHNTPFSLYSVLDGNGK
                     LIHNSVEYNLKKGMHFILPNDFGDFSFEGNLEIICSHI"
     gene            29890..31251
                     /locus_tag="PC465_001814"
     CDS             29890..31251
                     /locus_tag="PC465_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2649113.1"
                     /translation="MELFKAESKKYEKEFLKLLEQWVSIPSFYDRKTVSKDMPFGKGV
                     YDALNWFENLGRENNFKVKNIDNHAVQIEYGNGKEYVDIFGHCDVVNPGEGWDSEPFK
                     LNIIGDKLVARGVSDNKGPMIVNFLALKMIKDLDINLKRKVRLIAGGNEESGFKCIKH
                     YYSKEPYGVCGFTPDAKFPVLNGEKGGAIIKLISNIDDKSLYISGGIEFNTIPDKVYI
                     KNVEKLGKDNICFDINNISINYDNGNYIVYGKGGHSSKPEKSINPILATIKLLSENID
                     EKWTKDLYKLINQDNINGNLFGLNIEGKCGILSMVPTIINIVDGKLEVVLSVRYPEIL
                     TIEDIIKKFNLYMEQNNINKFELIGENLKQANYIDRNSKLVRSLHDIYIKYSGDLKND
                     VRVTSAGSYASEMNNSVIFGCEFPDGSFGNVHSANEFASLDRFITAIGIYAEAIITLC
                     NKI"
     gene            31339..33228
                     /locus_tag="PC465_001815"
     CDS             31339..33228
                     /locus_tag="PC465_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2649114.1"
                     /translation="MITKKHAIIVKSLSNKDGYMTSNELAIKLDVSTKTIKRYIADLN
                     SVLSKYDLVIASSRGIGYKLSGSKNNIARAIKEANKYIDGFLDDSEESRMSNIICMLI
                     NRNYMSIEAMAEELNLSIAAINKLSSKLKRKLEKYDLVIKSKPYYGSYIHGEEINIRQ
                     LITDYAIKLDEKSKVKVFLDDISENDIHCIESILEKHLREKDTIISDKDFNLLLSKII
                     VSVFRSKRGHSNNINLMDTSYRFHNYYFIENLMKEISDKIGFKLIEDEVIYISNYSGV
                     IAYKGTQGRKNTSEIEERISSVISSALQDIFLISGSDYTKDDEFMVAISDHIKRFLNR
                     ARANVKSNNPLLHQIKEKFPIAFNLAVFLSNKLETEFNLKLDEDELGYIAIHFAASNE
                     RMKKNTSKKICIVCHYGIGTGQLISEKLKQNISDLSVVGVYPVRYLDMAISQDVDLIV
                     STVELKGYEKPVLYIENIFDDSLIENVNKAFYEKEERRKIISNMFDEKAFFSIKASTK
                     EEVIISLSNKLKERDFIEESSIKSIIDRENISSTEIGNLVAIPHTIVKGDKKSIIGVG
                     ILENPIIWDKQEVQLVFMVFFNTKEKHNFSIFKYLYNFIKDEGGVRGIIKICDFNKLM
                     ALIGN"
     gene            33243..33698
                     /locus_tag="PC465_001816"
     CDS             33243..33698
                     /locus_tag="PC465_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2649115.1"
                     /translation="MGTNIFNKEYVFLNVDAKSKVEVLKFISKKAKDLNLAEDESLVY
                     EGLMAREEQFTTNLGESIAIPHTKNDAIENPAVVVLKFNEDVVWNEGEDKVKLAISLL
                     MPGKSKENIHLKLLSSLSRKLINKEFKDSLLKSDNVEEISNSINEALGL"
     gene            33757..34074
                     /locus_tag="PC465_001817"
     CDS             33757..34074
                     /locus_tag="PC465_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDF2649116.1"
                     /translation="MNKKLVALCACPMGLAHTFMAAEAIEQAAKALGYEAKVETQGAD
                     GVQNELTRDDILGATMIIHAVAITPEGMERFDGCEVYEVELQEAIKNAEGVIKEIEED
                     LGI"
     gene            34099..35361
                     /locus_tag="PC465_001818"
     CDS             34099..35361
                     /locus_tag="PC465_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDF2649117.1"
                     /translation="MAIKKKVINSSGASTTGGNNVGKSTPSSPTQSKGNGKWKEISKH
                     IMTGISYMIPVLVMGGLIGALSQLIPYAILGLDPSVGIVDAMNSGEFTGFKLSLLNIA
                     QLMSNFGFTLFGFAIPLFAAFCANSIGGKTALIAGFIGGYIANKPVGVPQFVDGQWTE
                     VVPVASGFLGAILIAFIIGYFVKWLNKSIKVSHNWLAFKTTFLIPLIASLACMVLMIF
                     IITPFGGLINESMKNFLTAAGAAGEYVYATALAAATAFDLGGPINKAAGFVALGLTTE
                     NVLPITARTIAIVVPPIGLGLTTLLDKRLVGRRVYDRQFYQAGKTSIFLSFMGISEGA
                     IPFALERPGFVIPLNIVGSVIGAITGIILGAIQWFPESAIWAWPLVDNLFGYIIGIAV
                     GAIFIAVGNIFYRNKLIKDGKLVVDYID"
     gene            35466..36530
                     /locus_tag="PC465_001819"
     CDS             35466..36530
                     /locus_tag="PC465_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2649118.1"
                     /translation="MDKIEKVREYFREYDIDGFLINSPTNKFYVGNLFSSSGYVFITK
                     ESQYIIVDFRYFEEIKRKSSLFNVVLMDKTRTHFDIINDICREQNIKEIGFEGNEVSF
                     DLYRSMSNKLSATLKSVDLSTLRETKNEDEIKYIKKACEIVDATFYHIVDFIKVGMTE
                     KQVENEIVRIIKALGGQKESFDTIVASGLRGALPHGKASEKVIEYGDFVTFDFGAKYN
                     NYCSDITRTICMGTINKELEEIYNIVRKANEECIRVLRPGMTTGEIDKVARDIIGSYG
                     YANNFGHNLGHGVGIMVHEYPALAPESNEVLKEGMIVTIEPGIYVPSLGGVRIEDDVL
                     ITQDGCMRLTTSTKDLIVVS"
     gene            36584..37762
                     /locus_tag="PC465_001820"
     CDS             36584..37762
                     /locus_tag="PC465_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HDF2649119.1"
                     /translation="MYNFDDKPDRVSEKCRKWDLNIIRDKFGDIREDFVPMWIADMDF
                     KIPTEIENKFIEAVRRGVFGYTYCYDEFYDSVIGWQKNMHEVNVEKEWITLTYGTVST
                     LHYVVQAFCKKGDSIILNTPVYDPFESSAKKQGVNVICNTLDVVNDRYYINFDKLEVQ
                     IKENKPKLMMFCTPHNPSGRIWTIEEMTRVATICKENNVILVADEVHAEHIHYGKFNS
                     ILKIGKELLENVILLTSPNKGFNLGGLKTSYSIVINKDIRDKFRNKLKQNSITSPNVF
                     GIIGLITAYNECHEWLSGVNEYIKSNYELLETWVNKYNKIKLMKMESSYLAWMDISGL
                     GISASEFTDKLAIDTGVLLEDGSHFVKDGEKYVRINLGTQKENVIEALNRMDLFLKSL
                     "
     gene            complement(37953..39011)
                     /locus_tag="PC465_001821"
     CDS             complement(37953..39011)
                     /locus_tag="PC465_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HDF2649120.1"
                     /translation="MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNE
                     VTVFNVKESKSDKILNECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVRVSDDTFF
                     VVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSEIQKLLPLIDYKNIILDE
                     KNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLEDGKNDK
                     PFKIGIQDPTSKNGESIGNIETTNKSVVTSGIYERFIEKDGKIYHHMLNPFTGYPFEN
                     NLSSVTIISDKSINCDALSTSTFGLGLEKGMDLINKIDNVDAIFITKDKKVYLTKGIK
                     DNFKLTDKSFSIEKLNKQ"
     gene            39078..39449
                     /locus_tag="PC465_001822"
     CDS             39078..39449
                     /locus_tag="PC465_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HDF2649121.1"
                     /translation="MKKKDILLILGILVVITACYGIINVINSKNAGNIEIYVDNKLYK
                     TVSINAKEEFKIENRGGYNIVKIHDKGVEIVDASCPDKVCVHTGFINKPSQSIVCIPN
                     RVSIKINTNEKNDNQEDIISK"
     gene            39486..40160
                     /locus_tag="PC465_001823"
     CDS             39486..40160
                     /locus_tag="PC465_001823"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HDF2649122.1"
                     /translation="MVNLGNDWDELLKEEFEKDYYLNLRKFLIEEYKTRQIFPNMHNI
                     YEALKHTSYKDTKVLILGQDPYHGDNQAHGLAFSVQPQVKTPPSLLNMYKELKDDLGC
                     FIPNNGYLMPWADQGVLLLNTALTVRAHEANSHKNKGWEIFTDRVISILSEREDPVIF
                     VLWGSNARKKVELIDTSKHYILEAPHPSPLSASKGFFGCKHFSKINEILKKLGKEPIN
                     WQIENI"
     gene            40409..41248
                     /locus_tag="PC465_001824"
     CDS             40409..41248
                     /locus_tag="PC465_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HDF2649123.1"
                     /translation="MNFKKLSNAKVSVMAVVLSVGILSGYSALNKQVTLVVRGEERTI
                     STFSSNVGDLLESQNISYDANDIVTLDENTKLSNGDKIEVIDVKEKTVVETKDIPFEV
                     TVVEDGSLLKGDSKVKEEGKSGKSELIYKETYHNGKKVEKEFVKKVVKAEPVNKVVSK
                     GTKVEMQVASSRGESSRRMASSSSSSSSSNNGKNMRVVATAYTGHSITATGTKPKWGT
                     IAVDPKVIPYGTKVYIPQFDMVFTAEDCGGAIKGNKIDIYMNDSKTVYNWGRKTIDIR
                     ILK"
     gene            41492..41588
                     /locus_tag="PC465_001825"
     tRNA            41492..41588
                     /locus_tag="PC465_001825"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41526..41528,aa:Sec,seq:tca)
     gene            41739..42446
                     /locus_tag="PC465_001826"
     CDS             41739..42446
                     /locus_tag="PC465_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HDF2649124.1"
                     /translation="MENNFTTRTSFLVGDDGIKKLNNSNIIVFGVGGVGSFTVEALAR
                     AGVGNITIVDFDDVDITNINRQIPALHSTVGRYKVDVMEERILDINPNINIKKIRSLY
                     NKDTSDEILTERYDYVVDAIDMVSSKIHLIETCEKKGLKIISSMGMGNKLDPTKIVVT
                     DIHKTSTCPLAKVMRKELRDRGIKKLKVVYSTEQPIELKKKVMNGRKVTPGSVSFVPS
                     VGGLIIASVIVNELLGQ"
     gene            complement(42588..43424)
                     /locus_tag="PC465_001827"
     CDS             complement(42588..43424)
                     /locus_tag="PC465_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2649125.1"
                     /translation="MRNKIFLSILIIISLLIGCDKKSLLSIHMIDVGQGDSILVQTPT
                     NKNILIDGGDEDSENIIISYLRQKRIKTIDIIIATHPDSDHIGSLDNIIKKFNVNSIY
                     MPEQSTDSEAYQNLINSCTDKNLSIQHLYKNDVLNIDNNINIYVLSPSYIQEESNLNS
                     IVFKLTFNDNSFLFMGDAEEENKKEILHSFKLNNINFIKIGHHGSNSSSSLEFIKKIS
                     PDIAAISCGYKNQYGHPHREVINNLKQNHVSIYRTDRIGDIVFYSDGEIIFTKYNYEI
                     DT"
     gene            43612..44517
                     /locus_tag="PC465_001828"
     CDS             43612..44517
                     /locus_tag="PC465_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2156 domain-containing protein"
                     /protein_id="HDF2649126.1"
                     /translation="MFFKDIELNSKKELDSYFDLVDYEACEYCFSTLYMWQHVYKTGY
                     YIGEDFAVLVGEYEGDSFSILPLAKKDKLPEVVDFVLEYFSKNNKKIYLRGITTEVVE
                     FLKEKYPGRFEYIEERDLFDYIYDAESLRTLAGKKNQKKRNHINYFLKEYAGRYEAKL
                     LDKENFDECLVLMKEWESNKEENNEFDESMDDELIGIKKIFNHYDILKDKVKVFGVYV
                     DGKLEAFSIGELLNPNMALIHIEKANPDIRGLYPFINQQFLVSEFKDVEFVNREEDLG
                     IEGLRKAKLSYHPCRFVEKYSVREA"
     gene            44526..45710
                     /locus_tag="PC465_001829"
     CDS             44526..45710
                     /locus_tag="PC465_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2649127.1"
                     /translation="MEIRYAKEEEIESIKDIWSYCFNDTESFMKYYFNDKYKSENTVV
                     ALDEGKIISSLQLNQYKLLLNSKVYNTSYVVGVSTLPEGRGAGYMNKVMKFTLNELYK
                     KGQLVSILMPIDYRLYRRFGYEHCYDQIEYTINTDDLKNFKSSGKMIKSNLSQIDDLI
                     QIDRTFLNEVNGNVLKDEHYYENLFKEIQSEDGFLYIHEGNEKDGYIVYFLQEDKMFV
                     RELFYKNIDALKSMLKFIYNHNTQCKIVTISTPTIDKIRFILDNPKDSDIKIKPFMMG
                     RVINVKKFIEDIDIENDINSSFNLLIEDKFIDENNGLFKISIQNKKVSVEQLDKKGAE
                     KPQEDFDIKLDINTLTQLSFSYIDVNEAIFLNDIKDVSEETLETLNCIFSKKNNYINE
                     YI"
     gene            45825..47126
                     /locus_tag="PC465_001830"
     CDS             45825..47126
                     /locus_tag="PC465_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HDF2649128.1"
                     /translation="MGVIIIQIRRPLLIILMFVVAISFIITNNTKNDEELNDKIITIQ
                     GVVKGKIEKKRYNQYKVGVFLINDYTKNKNLKIGQKVNITGKFKSLDKMKYDDFDYGR
                     YIKSTGYKGIVYINNYKIIDKNKLYSLIGEIKFYISKTYRYLYKKNSDFINSILLAEV
                     ENLTEEQKEIFTRTGTSHVISISGLHTGILCVIISFLLRGINKLYKLLILSIFITLYC
                     IMVGASPSIIRSIAFVMIFYLSIFIDRKKDGISALSLIGIILIMNNPYVIYNVSFQLS
                     FLATLSILIFYNKINSIIKLSMVSLTISSNILTLPIIYYTFKGIPLLSIIGNLIIVPF
                     VGVIMYLSIASLIVFKVSVVIAKIISFFNSTLIESIFFLLEKISNLSFAYINIENPKF
                     YIVVIYYIGVFFYIFYIEGKEIKEQENELQGYYKECKREKL"
     gene            47080..48123
                     /gene="holA"
                     /locus_tag="PC465_001831"
     CDS             47080..48123
                     /gene="holA"
                     /locus_tag="PC465_001831"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HDF2649129.1"
                     /translation="MNYKDIIRNVKEKNFEKMYLFYGREYYLIENAIKAFKDSLNEGM
                     LDFNLDIIDGKEIVLNQLISSIETLPFMDDRKIVIIKDFELLKGKKKNFTDSDEKYLI
                     EHLDNIPDTTTIVFVVYGDVDKRKSLVKKIGNNGIVFDCDKLSDMDLFKWIKKSFALN
                     DVIIDNSQIMYFIEQEGYRDKSSEKTLSDLENEINKISSFVGKGNNVTNDVIDKLSQK
                     KVENDIFKLIDYIGEQNASNAMKILNDMIQEGESVLGIFSMIARQFKIIMQVRQLQLD
                     GYSTKLIADKLKMHQFVVGKALKQTKNFSDDIIVEILNYILESDYKIKTGLIRDTLAV
                     EMLVSRYCKREAI"
     gene            complement(48310..48576)
                     /gene="rpsT"
                     /locus_tag="PC465_001832"
     CDS             complement(48310..48576)
                     /gene="rpsT"
                     /locus_tag="PC465_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HDF2649130.1"
                     /translation="MANIKSAKKRISVIEKKTALNRVRKSQIKTAIRRFEDAVAAGNR
                     EDAVAKFQYAQKRIYQVASKGTIHKNAAARKVAKLAQKLNGMNA"
BASE COUNT        19155 a         5272 c         8339 g        16046 t
ORIGIN      
        1 tgtgattaat taaaaaatta taaaaatcgt ttacatgttg atttttaaaa aaaaaagata
       61 tagaattata tagaaagtaa taaacaaaaa ttggatttac gggagtggaa tgaaatgatg
      121 aatgttacct taacagatgt aaaagaggct agagagacca ttaagaacat agtaaaaaga
      181 actgacttac ttgaaagtgt taaacttagc gaaaaaacag gagcaaatgt gttctataaa
      241 tgtgagaatc ttcaaaaaac aggttctttt aaattaagag gagcttgtaa caaaatagcg
      301 agtttaacag atgaagaaaa ggcaaatgga gttatagctt caagtgcagg gaatcatgct
      361 caaggagttg cattgggagc aaaaatgact ggtataaaat ctacaatagt aatgccagca
      421 actgcgcctt tagcaaaagt tagtgcaact aaaggttatg gagcagaagt agttttaaat
      481 ggtgcggttt atgatgatgc atatgcaaaa gctgttgaaa tacaaaaaga aacaggagca
      541 actttcttac atccattcaa tgataagtat gttatagcag gacaaggaac tatatctctt
      601 gaaattttcg aacaattaga caataaagtt gatactatac tatgcccagt tggtggagga
      661 ggaatcatct ctggtgttgc tgttgcagca aaagcattaa atcctaatgt aaaaatagtc
      721 ggtgttcaaa ctgcaaatat accttcaatg aaagagtcaa taaaaaatgg aaaagtaaca
      781 acagcattta atgatactac aatagctgat ggtatagctg ttaaaactcc aggagattta
      841 acttttgaaa taataaatga attggttgat gaaatagtag tggttgaaga gacagaaatt
      901 gcagaatcaa tattatttat gatggaaagt caaaaaatag tttcagaagg tgctggtgct
      961 gtatgtacag ctgctatatt aagtggtaag tatgtaccag caaaagatga aaatgtagtt
     1021 tgtataatat ctggtggtaa tatagacata aatacgttat atagaataat aggtgttgct
     1081 ttagctaaag aaggaagaag atattcattt agtacaatta tggaagataa gccaggaaac
     1141 tttgctgagt taactagaat aataagtgag aatggtggaa acattttaag tgctaatcaa
     1201 ggtaaattat cagcagggga agctctagga aaacaaagtg cggaatttat attagagaca
     1261 atagattatg accatatagc tagaataaag aaagctatag aagaaaaagg ttttaaaatt
     1321 atagaattat aataaaaagt gtatataata tacaagaaaa atagtataat agtgtatgaa
     1381 gatacatttt atgtgtatta gattaacgaa ttaggaggat tttaaaatga aacatgaagt
     1441 aatacatact aatgatgcac cagcagcttt aggaccatat tctcaagcta taaaagctgg
     1501 aaacttgtta tttgtatctg gacaagttcc tcttgtacca gagactatgg aagtagttga
     1561 aggagatgta caagctcaaa ctgctcaatc tttaaaaaat cttaaagcta tattagctga
     1621 aagtggagct gatttttcaa atgtagttaa gactacagta tttataaaag atatgaatga
     1681 atttggggct ataaacgaag tttatgctga atattttgga gaaaataaac cagcaagagc
     1741 ttgtgtagaa gttgctagat taccaaaaga cgttaaagtt gaaatagaag taatagctgt
     1801 attataaaaa tacaatattt ttaatttgaa aaggctgaaa aactatattc tagtgattca
     1861 gcctttttat aaaaaaataa atcacaataa agaacatgat aaatattgtc gaattaaaaa
     1921 ataaaattaa aataaatatt gcaatatttt tgagaaggtt ttataatgag tatataattt
     1981 gaaacgtgta actattaaat taggcatgag ttcttggata tttttatcct gaggattcat
     2041 gccttttttg tattgaaatt caaaaatcta tttaataagg aggaagtact gtgttaaatt
     2101 ttttcaagaa aaataaaagc tataagttac atgcagtagt gagtggtaac agcattaata
     2161 ttgagaaagt aaacgattct gtgttttcaa aaaagttaat gggagatgga gttgcaatta
     2221 ttcctaatag tgatgttgtt gtagcccctt gtaatggtaa agtaactgtg cttacagaat
     2281 caaagcatgc ctttggtatg gtctcagatg agggtgttga aatattagtc cacataggaa
     2341 ttgatacagt tagtttacag ggtgaggggt ttaaaaatga agtgtctcaa ggagatactg
     2401 ttaaaaaagg tagtccaata ataagttttg aaagagaaaa aataaattct cagggaattg
     2461 attgtacaac aataataatt gtattaaatc atagcgaatt ttcagaaata aattgcatgg
     2521 tagaaaatga agttgttgca gggcaagata ctgttattga aattatgaaa taataggaag
     2581 ggattaattc aatatgagag tagtaaaaat ctttaataat aatgcattat ctacagtaac
     2641 taatgatagg aaagaagcta ttttactagg tcttggtata ggttttaata aacgtccagg
     2701 agataaagtt aatgaagata aaatagaaaa gatttattat gttcaagacc acatgcaaac
     2761 aaaattttta gaattattaa aaaatgttag tccagaagtg atggatgctt cacaacaaat
     2821 tataagtctt ataccaggaa atgagggaaa atttaataat aaagggatat tatctttagt
     2881 ggaacatatt agttttgcaa tagatagaat gaaaaataat gtttttttac ctaatttaat
     2941 gcttttggat ataaagatga tgtattcaaa agagtttgaa ttaggagtaa aagctttaga
     3001 aattatatat agagtatgtc atatccattt gcctgaagat gaagcaggtt acatagcttt
     3061 acattttgtc aatttacaat caaatgataa tttggcatat gatactttaa aatttgtaaa
     3121 aggtagtatt gatttgatta aagaatgtta tggattagaa ttagacgaat cgagtttaag
     3181 tacattacgt tttagaactc atcttaaatt tcttgctcaa agaattttta agaatgaaat
     3241 ttgtcaggat gataaaatga ttgaaatgta tgattattta attaacaatc atcctaaaaa
     3301 taaagaatat ttagaaaagt taaatgtata tattgaaaag gagtttaggt ataaattaga
     3361 taaacctgaa aaaatttatc tactactaca cctaacaaaa atcttataag aatgagatga
     3421 attagtaata gaaatatata taattttagg gggggataag attgaaagaa aaactacttg
     3481 gaggactgga aacatttgca aaggcaatgg ttcagccatt aatgtattta tcgagtgcag
     3541 gaatattaat ggtggtaggt gtactactta caaatgatat gttattagga gtacttccat
     3601 tttttaaatg ggagccaatt caaatatttg gaagcctaat ttataactgt ataatggcta
     3661 ttattaataa tcttgctgtt atatttgcta taggtattcc tgctgcacta gcaaaaaaag
     3721 agaagcacaa agcagcgtta ataggattta tgagttatat aatatacctt acagcttcca
     3781 acactatgtt aacatcacta ggtcaactag caaaagaaag caagatgctt ggactgatag
     3841 ggactggaca agctactatt ttaggtattc aagttgtaga tacaagtgta tttggtggaa
     3901 ttattttagg gtgtatagct ggatatgtat ttaatcgtac aagcaacaaa acatttaaag
     3961 gagctttaca gatatactcg ggagcaaatt ttagttttat atgcatgttc tttgtatcca
     4021 ttttaattgg agttgtgagt aactttatat ggccattagc tcaacaagga atagcttctc
     4081 ttgcaaatgt catcaaagat acaggtacat ttggtttatt cttatatggt tttttagaga
     4141 gaatattagt accaactgga cttcatcatt taatttatac accatttcag ttttctgatt
     4201 taggaggagt gcttaaagtt ggtgcagata cagtttcagg agcctatgct atagttatga
     4261 cagaaatgaa tttaccagtt gagcgtttct cagatagtat atactatatg gcaactggat
     4321 ttacaaagat gtttggttat ataggtatag gagctgcctt tatttatact gcatataagc
     4381 aaaataagaa gaaggttaag gcaacgatta ttccactaat aattacagca gtattagcct
     4441 ctgtaacaga accattagac tttatgtttg tattctgtgc accactttta ttctttgtac
     4501 atgcagttat agctggtctt tttatagctt tattaaaaat atttgatgtt actgcattat
     4561 gtggagggaa cttattagta tcaattataa tgaatactac agtaggcgta gaaaaaacac
     4621 actggccagt aatgatgata ttaggacttg cacaaattat tgtatatttt gtagtattta
     4681 gttttttaat taagaaattt aattataaaa ctccaggtcg tgaagatgag agtacagcta
     4741 caggcgaaga acaatcaaaa caacttaatt tagatgcagg gatagaaaat ataattgatg
     4801 ggttaggcgg aaaagaaaat attaatacag tagaaaattg catcactaga ttacgtgtta
     4861 atgtaaaaga tgaaagtaag attaatgaag atataattaa tttaacgcca aatagcggga
     4921 ttgtaaggaa aggaaaagat atacaaataa tttttggact tcatgtgcat gaggtaagac
     4981 gtgcagtaga agatttttta gaagcttatt aaagatatat atttatatag caagggtaaa
     5041 taacagcttt aagtgctgtt tactatttat taaagataca tataatttat agaggaggaa
     5101 taattattat gattattact attgttggtg gaggaagcac atttactcca ggtattgtta
     5161 agtcaattgc attaagagaa aaagagttag agcttgagga aattcgttta tttgatattg
     5221 ataaaaaacg tcaagataaa gtagctgtag ttgtcaactg gatactaaaa gaagatgtta
     5281 aaacagatgt taaactaact gtaactaatt gtgaaaaaga agcgtataca gatgctacat
     5341 ttatatttgc acaaatgcgt gttggtaaat atgaaatgcg tgagcaggat gaaaaaattc
     5401 cattgaaata tggttgtgta ggtcaagaaa cttgtggttg tggagggatg gcatacggac
     5461 tgcgtacaat acaaccaatg ataaaggtta ttgatgatgt agagaaatat gctaaaaaag
     5521 attattggat attaaattac tctaatcctg ctgcaatcgt ttctgaagct tgtcgtaagt
     5581 taagaccaaa tgtaaggatt ataaatatct gtgatatgcc aatagctatt atagatatga
     5641 tagcggggtc attaaatatc aatgacgttc ataatatacg ctatgattat tttggtctaa
     5701 atcattttgg ctggtttact tcaatagatt ataaacatag agacttaatg gaagagatta
     5761 aggaatacat aaaagaaaat aaaatattat taccaaaatc ttatatagaa aacttaaata
     5821 aaagtcgtag tacaggaaat cgccatgctg taagtagctg gatacatgtt tgggaatctg
     5881 tttatacaat gttagaaagc ttcccaaaat atctgccaaa cacttattta acatactatc
     5941 ttttaagtaa agaaacagtg gaacattcaa acataaatcg tactcgtgca aatgaggtta
     6001 tggaaagccg tgaaaaagac ttatttgaag gtgtgagaca ttacttagaa actggagaaa
     6061 tttctgaaaa agcattttat gcaggtttac atggagattg gattagtgat ttggcagttt
     6121 caattaaaaa tgatacacgt agtcgttttt tagttataac tgaaaatcgt ggagctatac
     6181 caaacatgcc atatgatgca atggtagaaa ttccagcata tattggtaaa gatggtccag
     6241 aagttattgc tcgaggtcca atacctctat ttcaacaagg attaatgatg caacaactta
     6301 acagtgaaaa attgatagta gaagcttata tagaaaatag ttatgaaaaa gctttacaag
     6361 cattcacatt aaataaaact attccaagta tgaatgttgc taaagaaatt ttggatgaaa
     6421 tgatagaagt taataaggaa tactggccag aattaagata gtaggataaa agaaagggtt
     6481 tttatttaat cattagatat gttttcagag tcttttatca aaatgtattc acaaacatat
     6541 ggcaatatat taaaataaag agtgatattt ttagaagaat ggggtgatgc aatgaacatt
     6601 ataaataaaa ttttttggca agaagatagg attggcatga ttacaaataa tttagaggca
     6661 gatacacata gtcactgtat gttacaactg ttcttaggga tagaagacag cattgaaata
     6721 acagttaatg aaaaattagt taaatgtaat tgtatcatag tagataaaaa tatctctcat
     6781 tcattttcag caagaaaaaa agtttattac tctgctatta ttgaacctac atctatatat
     6841 gcagaacagc ttacctcaaa aatgaatgat tttggctact ggatatgtga caataatgga
     6901 ttagagaaat tacgtcaaca aggaactttt ttgatagata actctagtaa agaacaatat
     6961 ttaagattta tggaaatgct taataactat ttgaatatac ctataactct aaaacattat
     7021 gatgacagaa ttactgaatt gctcaattta ttacgtactt gtaattgtga taatcatact
     7081 atttcaagtt ttgcagataa agtgtctcta tcagcaagta gattatcaca tctgtttaaa
     7141 gaacaaatag ggataccttt aaaaagctat atcttatttc atcaaatgga gtgtgctttt
     7201 agagaattac tttctggaaa aaatgttacc gaagcttcta tgactgctgg attcgatact
     7261 ccatcacact ttgcagggac agttaagcga atgatgggaa tgcctgtttc tttatctttg
     7321 aaagatagcg agtttttgaa agtatattaa atattctcgt tatataatga agttgtacta
     7381 agaaaggggc tttgttatga ataaagaata tttagaagaa acaaaaatgt taaattataa
     7441 tgaaccacaa cttaagcttt tggtatcatc aaagaattgg ttggaattag atgattttca
     7501 taaaataaaa tctatttatg agtttgtaca gaatgatatt ttatttggat ataatgcttc
     7561 tgatatgtta agcgcaacac aggtattaaa tgatggtatg ggacaatgca atacaaaagc
     7621 tactctttta atggcattat tacgtgcagt gaatatcccc tgtaggcttc atgcttttga
     7681 tgtaacaaaa gattttcaac gaggagctac atccaaattg atttcactat tagcaccaaa
     7741 atatattctt catacttggg tagaggtatt ttatcaagat aggtggattg ctctggaggg
     7801 tgtcataact gataaaaaat atttagaagc aattcagaag aaatttttta atcatggtgg
     7861 aacgtttaaa aagtatgcaa tagctacaaa tgatttgaaa aatacatcta ttgattggga
     7921 tggtaaagat acttttatcc aaaaagaagc tatcgtgtat gattatggta tttttccatc
     7981 accagacgta tttttttcta ctcattcaca acatatgtca aaattaaaaa atttcatata
     8041 tgtacatctt atcagaaaaa taatgacaaa aaatgtatgt aaggctagaa acaattatat
     8101 tgataaaaat gaatgagtgt ttaagaggta actatatagg aaatatatag aataattaaa
     8161 actgtactgg ttaaaatgaa taaaaaggag ttatcacaga gcaaacttaa attgttcata
     8221 ggataactcc ttttctgtat taacttctaa taatttgatg tctttttata aaacatatag
     8281 atacaattaa accagtaaat gcaagagtag ctgctattga aaatgcaaca tctattccat
     8341 gaatgttaga cagcatgttt gaactcatat gagctttctt agtagcactt gtcattatag
     8401 taataagtat agcagaacct atagctccag atatctgacg gagtgtgtta ttaattgctg
     8461 tggcatgaga tataagttct ctatctaatg ttttaattcc ccatgtagtt aatggcatta
     8521 aaaccattga aataccaatc atacgaatac aatacatcaa tgacacatga attaaagatg
     8581 tatctctgcc taaaaaagcg aaggataaag ttcctaaaaa caaacatcct gttcctaata
     8641 ttgatagagc atgaggtcca tatttatcta aatgacgtcc tgcaattgga ttgagtacaa
     8701 ccatcaatat agcaccaggt aacattaatg aacctgaaga taatgcagaa aatcctctta
     8761 cagattgaac gtacagagga atcattaatg tagcagacat cattgaggca tatacaatca
     8821 taattaatat tgtagaaata agaaatggtt tatttttaaa aaccctcaat tctaaaaaag
     8881 gttctttaga ttttaattga cgcaatgtaa ataaaattaa tgacataatt cctattaata
     8941 ttggtaaata tgtggcaata ttagtccacc cataattacc ttgattagta aatccaatta
     9001 ataaaccacc aaaacctaga gatgatagta ctattgaagg tatatctaat tttagttttt
     9061 gagtttcccc aacatttctt aataaaataa atgatagtat aacatctaat atagcaatag
     9121 gggaaagaaa cagaaataaa ctatgccaac caaatgaatc tactaaccat cctgataaag
     9181 ttggacctat tgctggagca aatcctactg taataccaac taaactcata gctgcaccac
     9241 gtttttcctc agggcataaa tagagtataa taacttgtaa aagtggcatt agagaaccag
     9301 aacccattgc ctgcaacaca cgagcaatca acatagttga aaaattatta gaaaaaagtg
     9361 caataataca tcctatagaa aagatagaca ttgatgtaat aaataacttt ctagtactaa
     9421 atcgatttat taaataagct gttgtgggta caataatacc tgcaataagt agataaattg
     9481 ttgttaacca ctgaccaaca tcagcagtaa ttttaaaatc tgacattata ttaggtaatg
     9541 ctgttgacaa tagtgtttga ctgagagaac ttataaaagc accagtcatt acaattgcta
     9601 ttattaaatt tcctttttta ttgttacttt gggtttccat aatttataac gtctcctttt
     9661 ttaattgatt tttaatgctg ttcaataaaa gtacttttgg tcttaaagtg tcttcttttt
     9721 ctaaatatgc aatcattgca tccataatta aagaatcata ttgttgattt tttccctcga
     9781 cgtataattt ttttattgct tctagtaatt taggattttc aaggagagaa gtatccgttt
     9841 tgattagttc ttctatatct tgtatcgttt taaaaaatag cgatttatta tgaagggaaa
     9901 agtaaacttc atcttcttgt ttatgtaaaa acattgattt ttcaattaaa ggatttagat
     9961 tatccatatt ttctacaact aaatctagaa tttgtatagt aaatttggca ataaagtata
    10021 catttatttc tcttttttgt acatgaataa tgtatataaa ctgatgaatt agagcatcca
    10081 ataagaaaac taaatcaaat ataatttttt ctattttatc accatagtta tcaaataagc
    10141 ttagtttgta ttcattcaat aagttagctc ttgattttgt ttgcaattta cttgtagcct
    10201 tacgttgctc ttcagaaaag ttttctctta tataggtatt tatggtagtt ctagaaaaaa
    10261 tatttttcca tacagcaatt atctttctgt ttaacttttc tgatgatgga atgtcattat
    10321 tttcatttat ggaatgtata atttctaaaa acttttcatc ataataattg attatttcgc
    10381 agataaaact ttccttagtt tcaaaatgct tgtaaaaagt agctttagac attttacact
    10441 cttttacaac atccgatatt gaagtatttt gaaaaccttt ttggtcaaaa attttttgtg
    10501 caatagttat aatgagcctt tgtttttctg tcactttatt atctcctttc acgcaaaaac
    10561 gtttagtact atatagtacc tacaagtttt gataaatata ttatacatca tttggaaaaa
    10621 aaatcaatat atagactgta atatgaaatt tttgaaaaat ttgttgttat ttttagtcgt
    10681 ataaaaaaga aacttaagag tttcttaaga attgtttaaa gaagttgcaa taaattagtg
    10741 gtatgattat agtatgaaag agaatgtctt gaaatttttc tgtatcaaat tccaattatg
    10801 gaggtgtagt atatgaaaaa gaaaatttgt gtagcaataa tttttgctct atttatagtt
    10861 tttgtagaaa tgtttattga tagctctagc gaaggaagta aaattatgac agctgaatta
    10921 agtaaataca ggaaaggcgt aaatgtatta tcaataaaca atattatagt agcgaataaa
    10981 aaatatagtt tgcccaaaga ttattctcct caggaaagca gtgaagcgag agatgctttt
    11041 tataaaatga ataaagatgc tcaaaagtca ggattaaatt taaaagcttt tagtacatat
    11101 agaagttatg aatatcaaga tagattattt aagtcatatg taaaagaaca tggagaaaaa
    11161 gaagcaaata gattttcagc taaacctgga gagagtgagc atcaaactgg acttgctttt
    11221 gatattggag gagatgacca gtcttgttgg gcaaataaaa agttcaacaa tacaaaagaa
    11281 gctaagtggt tgtatgaaaa tgcatataaa tatggtttta tacttagata tccagaaggt
    11341 aaagagaata taacaggata tatgtatgaa tcttggcact atagatatgt tggaactgaa
    11401 catagcaaaa actttgcaat gaataatttg actttagaag aatatttaca tataaattaa
    11461 gagatggttt gttaaaatta ggttaaaata aaaaataacc tagactatta gctgtgtaaa
    11521 gtgatataat gtaaatacaa tttaagataa ctactcgaag gggagtagct tacacgaaag
    11581 tggtaattaa tcgtcaagac agtagaaata ctcggttaat tagcaaggga ttccttgata
    11641 gcaagacctt caaaataagc attaggtatg tttgttttgg ggtctttttt tattcaagga
    11701 atttttattt aaaaaaattt aaatttcaag tatacataag agcccccaaa cataaaataa
    11761 atttattgaa gaggagggca acaaatgtct tacaaaagta cttatcaaga agtaattaaa
    11821 aatttagact caagtttatc tggtttgagt aaagaaagag cagaagagtt gttagaaaaa
    11881 aatggagcta atgaattaaa agaagcagat aaggttccta cttataagct tttcctagaa
    11941 agttttaaag acccattagt aataattcta ttgatagctg ctttagtaca aatattttta
    12001 ggtgaaacag tggagtctat aataattttt gcagttatta ttataaactc tgttctgggt
    12061 gttgtacaaa caaaaaaagc agaaagttca ttagaaagtt tgaaaaattt atctgcacca
    12121 aacgcaaagg taataagaga caataaaaaa atgacaattc cagcaaaaaa tttagtagtt
    12181 ggagatattg tattcttaga agctggcgat tacataccag cagatggaag gcttatagaa
    12241 gcacaatctc tcaaggttgt agaagggatg ttaactggag aatcagaacc agttttaaag
    12301 catacagaaa aaataagtga agatgtaagt ttaggtgacc agaaaaatat ggtatttagt
    12361 ggtgctgtag ttgtttatgg tagaggttct tttgtagtga ctggaacagg tatggatact
    12421 gagatgggta aaatagctgg gcttttagaa agtgctgaaa ataaacttac accattgcaa
    12481 caaaaaatag aggattttag taaaaaactt ggtgtaggta ttgtaatact tgctctttta
    12541 atatttataa ttcaagtagc aagaaattac tttatggctg gaaatggaga aatgacacaa
    12601 attattttag attcattcat gttctctgta gcagtagcag tagcagctat accagaagct
    12661 ctatcatcaa tagtcactat agtattggct gttggaacaa atagtatggc aaaaaaacaa
    12721 gccataataa gaaaattacc agcagtagaa actttaggtt caacaagtgt aatatgtact
    12781 gataaaacag gtactcttac acaaaataaa atgacagtag ttgattatta tatgtatgga
    12841 actaataatg atgagttaga taaagaaaaa gtaaactatt cttatcatgc taaattattg
    12901 actatggttt ctacattgtg taatgactct catataacta gtgatggtaa agaagttggt
    12961 gacccaacag aagtggcttt aataaattat tcaagtaaaa atgatttaga ttatgataaa
    13021 ttaagaagta agtatatcag aataaatgaa ataccatttg actcagacag aaagcttatg
    13081 tctactgtaa atagtatata tggagattat ataatgttta caaaaggtgc tccagatatt
    13141 gtgtttagta gatgtaaata tgctttgaaa aatggttcaa aagtagatat aacagatgag
    13201 ataatagaag aatataaaca taaaaatgaa gagttctcaa atagagcact tagagtatta
    13261 gcttttgcaa taaaagatgt cccagaagaa gattttatac cttcaattga tgacgaacat
    13321 gacatgacat tggttggaat aatggcaatg atagacccac caagagaaga agtaatggat
    13381 gcagtaaaag aggcaaagag tgctggtata aaaactgtta tgataactgg tgaccataaa
    13441 acaacagcag cagcaattgc aaaagagatt ggtataatgg aagaaggaga cttggctctt
    13501 actggaaaag agcttgatgc tttgagtgaa gaacaactat atgaaaaact agaaaatata
    13561 agtgtatatg ccagagtctc gccagaaaat aaaattcgta tagtaaaagc atggcaacat
    13621 aagaataata taacagcaat gactggtgat ggtgttaatg atgcacctgc attaaaacaa
    13681 gcagatatag gaatcggtat gggaagtggt actgatgtag caaaagatgc ttctgctatg
    13741 gtattggttg atgataactt tgcaagtata gtaaatgctg ttgaagttgg tagaacagta
    13801 tacagtaata taataaaatc aattacttat ctatttgcag gaaacttagg agctatagta
    13861 tccatagtat ttgcagtgtt tgcaggttgg tcaaatccat ttacagcttt acaacttttg
    13921 tttataaact tagtaaatga ctctttacca gcaattgcat tagggtttga aaagtcagaa
    13981 aaaaatataa tgaataaacc tcctagacac ccggatgaaa gtatactagc aggaggaaca
    14041 ttgaaggcag ttgctataag aggttgtata ataggtgtag ttacaataat tgcacaatat
    14101 ataggattac aagtatctcc agaacttgga gtagcaatgg cattttcaac attgatatta
    14161 gctagaataa tgcaaacatt acctgcacgt tctaataatc aaacagtaat aaaattaggt
    14221 tttttcagca ataaatacgt tataggagca gttttagtct gtcttgggct ttactcttta
    14281 acactaatac cagtgctaag aggaatattc tctataccaa caacgtttgg attgtaccag
    14341 ttggggattt gcctagggtt agcattaatt tcatcaatat taatggaact taacaaatta
    14401 ataaatagaa gtgaagtaaa ataatcaaaa aattaaaggg catattgatt ttaacaatat
    14461 gccttttata aatagtctaa tttattctat attatcgatt atttggaatg cttttataac
    14521 ttcaggtaat tctttttctt caggcattct aaatcttatg aaatttttat caagtccagt
    14581 aaaatcactt ccagatataa ctcttatttt taatttagca aactcttgtt gtaaatctat
    14641 gtccttgttt ttatgttcaa ctgtcataat tgatacagta tcactagttt cagctatatt
    14701 aaggtttttc catggaatta ataattgatt ttttatatct tttgtttttt cttttaattc
    14761 ttctataaat tgaacatcat ctaataaatt tgctgcaata ctacgagata tttcagacac
    14821 ttcgtaagga gtagaaatct ttttaatagg gctaacaagt tgttctggaa gaactgcata
    14881 tcctgctctt agtcctgcta aaccaaatcc ttttgaaaat gtttttaaag caattacatt
    14941 atcataatta tttagaagct tgacagctga attttctttt ggcatgtatt caccataagc
    15001 ttcatctacc ataactgcta tatcatattt agctgcttcc tttactatat tttcaattga
    15061 tgataaaggt ataatttgtc ctgtaggatt gtttggattg tctatgtaaa ttactttata
    15121 ttctggattt attttttcaa taaattcttt ttcattaaac ttgaaattat cctctttctt
    15181 taaaagaaca taatcataag ttgcaccatg catttttata tctgtctcat attctgagaa
    15241 ctgaggtgaa tatcctaaaa ctttatctcc cttttcaata aatagtctat ttaaaaggta
    15301 aataacatgt atagaaccat ctgccaaaca aattctgtca gtatctaatg ctataaaatc
    15361 tttccaataa tcgactatat tatcttttaa agcaattgaa tgaggatatc ctcttatcat
    15421 atcaaatttt aaagcattaa aagcttctac agctttgttt gagtaagaca cggtatttat
    15481 accttcacca cagtctatct cgaatacatc ttctgaatgt ccagattcta ttgcataact
    15541 ttttttcaac tgcatttcaa tagctttgtt aatttttagt ttcatacttt atcactcctt
    15601 atttagtcaa taataaatgt tataaaagtt gctagattta aaatattatg aaaatatata
    15661 atagtaaaaa tgaatataaa tattataata gctcacttta tttaatatga ttatatatca
    15721 tatattgtaa aatttctagc attataagac tataaattga aaatattcag aaaaatacta
    15781 caagaaacga tttattttgc tcttaaaata agttaaatga atgttattaa ttttgtaaat
    15841 tgaaatagtt taagtataaa gttatgatat aatctaataa gggtaattct ttagattata
    15901 ttaaggaaat ataggtatac aataaaaagt tatggagttg gattatggga tataaattaa
    15961 ttgtaacaga tatggatgga actttattag gcaataatca taaagttaca gatgaaaata
    16021 aaactgcact acaaaaagtt ataaaaagcg gtattaatgt aactttagca acaggaagag
    16081 ccttcgattc agctaaatgc aatgtagatt ttcttaaaga ggacatgcca ataatagctt
    16141 gtaatggttc attaataaga gagcaaaatg gaaatataat atattcaaat aagattgata
    16201 caagaacatg tttaaacatt ttagatgtat tagataaata cgatatttac taccaatgta
    16261 atagtataga ttctatgctt tcgaaaaaaa tagaaggacg tgaagataga ttaagtgtat
    16321 ttttaggctc tgaaacagaa gtaattgtaa aagatgattt gagagaagaa atctttaaaa
    16381 aagatatact aaaatttgta atcatagaag aaaaaaatcc atctattttg gatgaaataa
    16441 gaaaagaatt gagaaaagtt caaggaataa agataacttc ttcatggcca aacaatattg
    16501 aagtcatgaa tgaaggtgtt gataaaggta atgcagttaa aattttagct gaaaaaatga
    16561 atatagacag agaagatata attgcatttg gagacaatta caatgacata gaaatgataa
    16621 agtttgctgg tcttggggta gctatgggaa atgcagaaga attgattaaa caagaagctg
    16681 attatgttac agatacaaat caagacagtg gagttgcaaa ggcaatttat aaattcctag
    16741 agttaaaaga atcacttagc tcttaaaaca gtatataata ggaaaaaata ggttgactat
    16801 tttgtagata gtaattataa tacaaataga taaaacataa aaatttagat tcagtgaaaa
    16861 agagagtaga tatagagaaa atctcagcga attgggggat ggtgtgagcc taatgataac
    16921 actttatatt gaaaagaact ttggagaata ctacttgaaa ttcagtatgg tagtaggtaa
    16981 tctcgcctta agagaataga gtgggtaaac attgtttacc aactagagtg gtaacacgga
    17041 atatttcgtc tcttggtctt tttgaccaag agatttttta gtttcattga gttacaagac
    17101 ttataattaa aatacaaaaa attaaaatat gaggtgaaag ttatgaaatt atggggcgga
    17161 cgctttagaa aagcggaaaa tcaacttatg gaagaattta ataaatcttt tggctatgat
    17221 tgtgtactgt acaaaaaaga tatcgaagga agtgtagcac atgttcatat gcaagtaaaa
    17281 tgtggacttt taacagaaga agaaggaaag tctataacag aaggtttaaa agggatactt
    17341 gaagatgtag aaaatggaaa gttagtattg gatggagagt atgaagatat acatagtttt
    17401 actgagataa atttaattca aagaattgga gatgttggca agaagcttca tacagcacgt
    17461 agtagaaatg accaagttgc agttgatatg agattgtatg ctaaagaaaa agcaaatgat
    17521 ttggtggatt taatatctga atttaaagct actataaaag atgttgctga caaaaaccca
    17581 gtgatgatgc caggctatac tcatcttcaa agggcacaag tagtgacatt taagcatcac
    17641 ttaatggcat attatagtat gtttgataga gatgagaaaa gaataaaaaa tgctatagaa
    17701 atattagatg aatcaccttt aggctgtgga gctttagcag gaactacgca tgatatagat
    17761 agaagtataa cttgtgaaca attaggattt aaaaaagtag tagataattt tatggatgga
    17821 gtaagtgata gagattattt actagagcta atgagtgatt tttcaattat aatgatgcac
    17881 ttaagtagat taagtgaaga gttgatactt tggagttctc aagaatttgg atttgttgag
    17941 atagatgatt tatatacaac tggaagtagt ataatgcctc agaagaaaaa tccagatggt
    18001 gcagagctta taagaggtaa gactggtaga gtatatggaa acttatttgg tctttttaca
    18061 gtaatgaaag gaataccatt agcatataat aaagacatgc aagaagataa agaaggtttt
    18121 ttcgatagtg tacatactct tgaaatgtgt atacaaataa tggatagaat gatagccaca
    18181 ctaaaggtaa atgaggataa aatgaaacaa gcagtaaaaa atggtttttt aaatgcaaca
    18241 gaagttgcgg attatttggt taaaaataat gttgctttta gagatgcaca tggtatagta
    18301 ggaagtatcg ttatatattg tgaagataat aaaaaagcaa tagaagattt aacattagaa
    18361 gaattacata agttttcaga tgcttttaag gaagatattt atgattttat cgactatgag
    18421 agtatattaa ataagggaat aaaaaagaat ttaaaataat gtatttattt ttaaaagctg
    18481 taaatttgaa tgttatcatt taaatttaca gctttttatt gtgtaagatt ttattatata
    18541 aaagtaagaa acttaaaagg agtagtattt aaaataaata caaataaaaa attattatta
    18601 aaatgataat taatatcaat aagtattgac aaaattattt ctaaatacta ttatatataa
    18661 tataaataat aatgaaaatc aatatcaaat aaatgggagg aaatctaatg aacttattag
    18721 tgattggtgg tcatgaaaga atggaaaaag attatatggt tatggccaag aaaaaaggtt
    18781 ataagacaaa ggtatatact accatgtcat ctaaattaaa taattctata ggaagaccag
    18841 atgcagttgt catacttaca tcaactgttt cacataagat gtctagaacg gttgagtctc
    18901 aagctaaaaa acaagatata ttaatcgtaa ggcataaaaa tagtagtaag gtagcattta
    18961 atgaatgtct agatatggtt gatgaatgtc tgggaaattg ttcaaaatgt aagcttaaag
    19021 acaaacaaaa acaaaaaaat atataggtat aaaaaataca taaacataaa attaaaagta
    19081 ctgagataat agttataatt attatctcag tacttttaga tttataagga taagtatatt
    19141 ataaattttt tattataatt tctaactact tgttactttt tcatattttt tttacttcta
    19201 gctttttttc tttttttctt ctttatattt gaagctatta taaataaaac taaaagcact
    19261 agaatacctg caataatctt aacaaaagtc attaaaacat tattttcagt caaaaatgga
    19321 agactgctat caagattatt ttttgcaatt aagtctatac tgttttctag tttaccatta
    19381 ttatatacat ttaaagtacc aaccttagct ccttttttta taggcaaatc aattttattt
    19441 aactctgttt tggtatcata attgccttga gattcatctt tttctaagaa tatcctataa
    19501 ctattttttg gttcataaat caattcatgt tgttttgtaa acaatacttt tttagtatct
    19561 gtgtattttt ctttatcaac aatagtagca cacttaaagt tatcaaatcc ataatcaatc
    19621 agaatacgtg agtctaaata taaatcagca ttagttgaat taaatacagc aacgataact
    19681 cttctgccat cttttacagc actcgataaa agacatttac cagcagcatc agtatatcca
    19741 gtttttatac catcaactat atcatatttt atatttatag gttgaccttt gtatgtaatc
    19801 ttatcatgtg atgtcaaaaa cttattagtg tttacaaagt atctctcata aggatatgct
    19861 tttgtagctt caaatttaag tgacttagtt tttacaattt gtctaaaagt atcattattc
    19921 atagcttctc tagctatgag agccatatca tgagctgttg tgtagtgatt tgggtctggt
    19981 aatccatgag gattattaaa atgagtatta gtagctccaa ttttttttgc ctcagagttc
    20041 attaggtcaa taaatttttg tacattgcca ccaccaacat atctagctaa tacaaaagca
    20101 gcatcattag cagaatgaac caaaagagca tctagtaact gctttacagt aaaagattcc
    20161 ccatttttta gatacatact agagccatct atttgaggta aatctttaat ttctattact
    20221 tgatttaaat ctttaacctc ctttagaact aaacaagctg tccatacttt agttgttgaa
    20281 gctggataaa gcttagaatt tccatcctta ttatatagta ttttgccaga ctcatagtcc
    20341 attaaaactg catgtttagc aactatagct ggttcattat ctgcaaaaga gatattagag
    20401 cttcctaaaa atgaagtaaa tatcaataaa cagattaata aaagtgataa atttcttttc
    20461 attgtgagcc tccaaatttt aaattcatct tttagtatag catatatttg tcaataatta
    20521 aaagaaagga gtgattaata tatgaaaaaa aaggtaaaat ttatttcgtt ttttgtttta
    20581 tttattttaa taatatcatc aataatcgtt tataaatcgc ttattttcaa agatgatatt
    20641 tatgttgtaa gtaaaaaaaa tttacctaat gaaaaaacac atgttgtaga gaatgaaatt
    20701 aaaggtgaag ataataatca caataaagta actaaagaca tagataaaaa ttttcaaaat
    20761 aataaaataa ctatatacat aagtggagca gtaaatagac ctggaattgt aactatagag
    20821 tcagacaaga gactttatga tgctgtagaa ttactaggag gaacgacaaa agaagcagat
    20881 ttaaatggag tcaatctatc agtaagatta gaagatgaac aacattacat aatacctaaa
    20941 ataggtgaag caacatctgt tacaagtaat gatgattcca ataaaccaaa tcagaagaat
    21001 gagtcaagag gtgagcctaa aaataaatcc aataaaaata tatctaacga atcaaaagta
    21061 aatataaatg tagcgactat agaagagttg gattctctac ctggggttgg agaagctaca
    21121 gccaataaaa ttttacaaca cagagaagaa aatggacagt ttagttcaat tgaggaaata
    21181 aaaaatgtaa atggtattgg agataaaaag tatgaaaata taaaagattt aatttgtgta
    21241 gactaaaata taatacaaaa cttacatata gatatgttat tataaatatg tatgtatatg
    21301 tgtgtacatg tggaaattta gtaaaggagg cacttttatg aaaaaagaac aaaaaaaact
    21361 tacagagatg acaacagcag gtggttgagc cgctaaaata gggccagagg ttctggcatc
    21421 agttttatct caattgccta aaaatgataa tatagaaaat ttattagtag gactagatac
    21481 agcagatgat gctgcagttt ataaattaaa tgatgatatg gcacttatcc aaactttaga
    21541 cttctttaca ccaatggtag atgacccata cgtatttggt caaattgctg catcaaattc
    21601 actatcagat gtatatgcta tgggaggcaa acctttggtt gctatgaata ttgtttgttt
    21661 tccatcatgc catgatatgg atgtacttgc agaaatatta aaaggtgggt ttgataaagt
    21721 gaaagaaagt ggagcacttt tggttggagg gcatactgta gatgacaaag agcctaaata
    21781 tggtctttca gtttctggga ttgtaagtcc aaataaagtt ttatcaaatg ctactgcaaa
    21841 acctggtgat aagttaatta taacaaaacc aattggagtg ggtgtattaa atacagccat
    21901 gaaagaaggt atggtagaac aacatatagc agataaagta atagaaataa tgatacattt
    21961 aaataaatat gcagcaatga gttttgagaa atttgatgta aattcggtta cagatataac
    22021 tggttttggt ctacttggtc atactttaga aatggccaaa gcttctgaag taagtattga
    22081 aattgaatca aaacatgtac caattattga aggtgcaata gaaatggcac aaatgggaat
    22141 tatacctgct ggtatgtata aaaatatgca ttatgtatct aaagatgtag aagttgtagg
    22201 aaatatagaa gttgcagttc aagatatttt atacgaccca caaacatcag gagggttgtt
    22261 aatttcagta aaagaagaac ttgcagagga acttgtaaaa gatatgaaat taaatggagc
    22321 aatagaagct aaaattatag gttctgtagt tccaaaaggg gaaaaatata ttacagtttt
    22381 ataaaatatt atagagaaag agtgattgtt ttgagcaaaa gagaattgtt tgcaatgttg
    22441 ccttcagttg atgaagtatt aagtgataat agaattgtag aaataataaa tgaatatcct
    22501 agaagtttag ttttagaatc tgtgagagaa gtaatagatt taaaaagaca atttatatta
    22561 agattaaaag aagatgcatc aaactctgta acaatagagt ttggtgaaat aatagaatct
    22621 gcaatagaga gagttaagtt aaattactca ttatctttaa aaaaagttat aaatgcaact
    22681 ggtacagtta ttcatacaaa tttaggaagg tctttactta gtgaagatat aaaagatgaa
    22741 ttatggtgtg ctgcttcaag gtattcaaac ttagaatacg atttggataa tggagaaaga
    22801 ggttcaagat actctcattt aactagtaca ataaaaagac ttactggagc agaagatgta
    22861 ctagttgtaa ataataatgc agcggcagta cttcttgtac ttagcacaat ggctaaagga
    22921 ggagaagcaa ttgtatctcg tggagaatta gttgaagtag gtggttcatt taggattcca
    22981 agtataatgg ctcttagtgg tgcagaatta gttgaagttg gttcaactaa taaaactcat
    23041 ttgaaagatt acaaggaggc cattacagaa gatacaaatg tattgatgaa ggttcataca
    23101 agtaattata gaataatggg attcacagag agtgtttcta tagaagaatt ggttaattta
    23161 ggtaaaaaat ataaactacc tgtaatagaa gacttaggaa gtggagtttt tatagattta
    23221 tcaaaatatg gtttatctta tgaaccaact gtattggatt ctattcgaca aggtgcagat
    23281 gtagtaactt ttagtggaga taagatgctt ggaggtccac aagcaggtat tatagttggg
    23341 aaaaaagagt atatagaaaa aatgaagaaa aatcaactta ctagagcact tagagttgat
    23401 aagcttacaa tatgtgctct tgaagcaaca ttgagaatgt atttagatga gacaaaagct
    23461 atagaaaata tacctacttt aaaaatgttg acatataaaa ttgaagaatt agaagtaaaa
    23521 gcaaataaac tatttgaaaa aataactgct ttaaacttaa atgcaaacat aaatatagaa
    23581 gatggatttt cacaggtggg aggagggtct atgcctcttg aaactataag tacaaaggta
    23641 atatcaataa ctcctgaaca tatgaatgtt tcatctttag aaaaaaaact aagacttagt
    23701 gaagcacata taatagccag agtgtatgat aataaatatg tactagatgt aagaactata
    23761 tttgatgatg aatttgatgt aatagttgag gaattgagaa aagcatttaa ttaaataaat
    23821 ttgagttaat aaatattaaa tttagaagta taagtatgaa gttttaatta aaaaatagct
    23881 acacacactt gtgactttag tcatagcagg tttagagggg gcaaaaaatg aaaaatgtag
    23941 taattggaac agcaggtcat attgaccacg gaaaaactac tcttataaaa gcattgactg
    24001 gaagagagac tgatacatta gatgaagaaa aaaagagagg tatttcaata aacttaggat
    24061 ttacttattt tgatttacca aacaatagaa gagctggaat tgttgatgtc ccaggacacg
    24121 aaaaatttat aaaaaacatg ttagctggag catcaggaat tgatatagtt ttacttgttg
    24181 tagcagcaga tgaaggagtt atgccacaga cagttgagca tttagatatt ctaagctttt
    24241 taaatatcaa aaatggaata gtggttctaa ctaagtctga tactgtagat gatgaattta
    24301 gagagctagt aaaagaagat atttgtgaaa aaataaaagg aacttttctt gaagatgctg
    24361 aaataattga agttgattct atatctaaaa gaggtataga cactcttatt gaaaaaatag
    24421 ataaaatgag tgatgatata gaagataaaa atgaaaattc tccagcaaga cttaatatag
    24481 acagagtatt ttcaataaaa gggtttggta ctgtaataac aggcacttta atagaaggaa
    24541 agataagtat agaagatgat ttggttatat atccacaggt attaaaaaca aaaataagaa
    24601 gtatacaagt tcatggagaa aataaagata cagcttatgc aggtcaaaga acagcaatca
    24661 atatatcaaa tgtaaaagtg gatgatataa aaagaggaga tgttttagct gcaccaaact
    24721 cattggagga atcaatgatg ttagatgtaa aattatcatt ggtaaatcat ttagataaag
    24781 gattaaagca ctgggataga ttaagattgt atcatggaac tagagagata ctttgtagag
    24841 cagttccact agataaggaa ttaattgaaa gtggagaaag tggctatgtt cagttgagac
    24901 ttgaagaaag catagtatct aagaaaggtg atacgtttgt agtgagacgt tattctccaa
    24961 tggaaactat aggtggaggt gtaataattg acccatctcc taaaaaacat aagaaatttg
    25021 atgaaaaagt tatagaagca ttaaaaataa aagaaaaagg cgaactaaaa gatataatag
    25081 aagagtactt aaaaaggaat ttaaaaaatt atccaaatat aaaagaaata atgagctata
    25141 gtggtgctca tgaagaagat gtaaaaagag cgcttgaaac acttatatca gaagataaag
    25201 tatttattat aggaaatatg tatatgcata taaatcaata caataaatta aaagaaaata
    25261 caataaagct tttaagtgag taccataaga agtataggct tagaaaaggg atactaaaag
    25321 aagaagtaag gtctaagata gagagtaatt ttaagactag ggagatggat attttattag
    25381 aaaaattgtc tacagaaaat gctataaaaa tagaaaataa tatagtatct ctattagatt
    25441 ttgaggttat tttaaatgat aagcaaaaag aaatagcaaa aaaaatagaa aaaagattaa
    25501 aatcatgtgg agtttcttct atactgacaa tagatgaagt ttctgaagga aatcataact
    25561 atgctgaagt attggagtca atgataggta ataaagtaga gaaattagat gatttgtata
    25621 taatggacaa agatatttat gaaaatgcaa agaacatttt gataaattat ataaaagaaa
    25681 ataaagaaat aacattagga gaatacagag atttgattga ttctagcaga aagaattgca
    25741 tgattatatt ggaaaacttc gatagaaaca aaataactaa aagagtagaa aacaaaagaa
    25801 ttttgtttta gcagaaaatg tctgtttttg ctttaaggta taaagaagga attataatgt
    25861 cgagtatcgt ataattaatt agtataaaat attaattaag aggaagtgta aagtattgaa
    25921 gaatataata cctgatgtaa aaccagatat aaaagaaaga gaagacatga gccttttatt
    25981 tataataatg ggctcagtac ttttattatt tattataaaa gatatagaga aatatgaaac
    26041 tttattacat gccatatata cgatattttt agtagctaca ggagtaatta tatttaatac
    26101 tacaaaattt aaagtagatt cattttctac atttttagga ttaattttta tagctactgg
    26161 agtattggag tgtatatatt tatttaattc cttggggatt aaaactaagt ctataatgga
    26221 gattaacatc acaatatcag caataacaga tttatttcct atactgggtg tatacttaag
    26281 ttttaaattt gttaaggata acaaacaaat ttattcaagt gtaattttat ttatagcaac
    26341 tgctacatta acaataacat ctttattcat aatatcagga atttgtgact atctgggaaa
    26401 tggtaaatca caatatgctt taggagttat aatatctata ttcataataa ttatttctat
    26461 tgttagtgga attgaattaa attcaagttc aaataaaggc aaatgggaat atgatgaaaa
    26521 aaagattttt aacagaataa tagtaataat aatcttatca agagttccaa atctattgca
    26581 tatagttatt gataatagaa atgtagagag gatattatcc cagataataa taaatgtagc
    26641 cttatattat ttatataatt acatagtatc taagaatatt aagaaaacag cactggaatt
    26701 gcatgatacg aatgaagaat taacaaaaaa aacggaaagt ttaaaagaaa agaataaaaa
    26761 attaatctat gagacagaaa agatagagga acttaaggga atacttatga aaagagaatc
    26821 taggctacaa tctacattag atgtagcagt aaatagcata gtagtattta gcaaagatgg
    26881 agaaattaca tatgcaaata agagctttag aaatactttt ggagactata aagaacaaga
    26941 taaattgact gataaaataa aaaacttcaa tgatttgata gaaagcattc attatgtgtt
    27001 tgttcatgag aagaatgcag agaaacttat tagtacaagc gataataaag tttatcaagc
    27061 tatatttgca cctttaatta ttgcttcaca aacagaagga gtattgtgtg tactagaaga
    27121 taagactaag aaaaaggagt acgaacgcaa acttattgaa gcaaataaga gaagtaaaga
    27181 ttttttagaa agtattggag atggcatagt agtgcttgaa ggtaataaca aaatatatgt
    27241 taataatgca tgtagggaaa tttttaaaaa taatttagag agtattgatt tttcattagt
    27301 atgtaaaagt gaagaaagta tagaaaaaag atatgtaata gatggtgaag taaagtatgt
    27361 agagatgagt ttttctcagt atactaatgc tggtactaat aaaactatta ttgtaatacg
    27421 tgatacaacc tctcgaaaaa tatctcaaat aaaacttgag gaaagtcaat catcatattc
    27481 aagatttata gatatattac ctgatggcat atgcttatta aaagaagatt taagtataaa
    27541 ctatgcaaat aagtcgtttt tagatatgct agcttttaca aacatagatg atataaaaga
    27601 ttctaatatt aaactattaa tgaatgcgaa tactgaagaa aaaatgaaat ttacggataa
    27661 tatggctaaa gttttaaatg aaaatagaag tatactttta ctggaatatg aattgataaa
    27721 tagttatgat gatatagtag aagtagaatt aagtgcatta ccttttgcta tatacaatac
    27781 tagatacata atgcttatta taaaagattt agtacataag aaatattccg agcaagcaga
    27841 aaaagaactg cttgaaagat ttaaaacaga taaaatcaaa acggagtttt ttgcaaatat
    27901 gtctcatgaa ttaaaaactc cactaaatgt tatatctagt tcaaatcaac tggtagattc
    27961 tttctataga aatgaaaaga taaaagatta caataacaat attaaatctc atgtggattt
    28021 agttagacaa agttcttata ggcttcaaag attaataaat aacattatag atttaacaaa
    28081 gatggagtct gggttctata cactaaaact tgcgaaatac aatattgtat ctgtaataga
    28141 agacttattt atgaatatag aagagtatgc acttagaaaa gacataaaaa ttctttttga
    28201 tacagacctt gaagaaatta atgtttatat agacaaggtt gaaattgaga gaattatgtt
    28261 gaatctattg tcaaactgta ttaagtttac tgataatgga ggctggatat atgtaagtat
    28321 tcattataaa atagataaag taatcataag tgtaaaagac actggagttg gaataccaca
    28381 agataaatta gaattgattt ttgaagaatt ttcacaagtt gataagactt tatccagaaa
    28441 tactgaagga agtggaatag ggcttgctat agttaagaat ctagtaagtc ttcatggtgg
    28501 agatatagaa gtagtaagtg aagtgaataa aggcacagag ttcttaattt cacttccaat
    28561 gaagggattt agtagtgaac attacacaga agataagaga atatataata ttcaagaaaa
    28621 aataaaaata gaattttctg atatatacta ttaaaaatga ttatgagcaa aaataaaata
    28681 aaaatactat ttgtttaaat atttaagttg taagaaatag gctatcataa ggtaaattat
    28741 tatgatagcc tatttttagc taggttttat atctatatgt gagaacatat aatctctaaa
    28801 ttaccttcaa aactaaaatc tccaaagtcg tttggtagta taaaatgcat accctttttt
    28861 aaattatatt ctacagaatt gtgtataagt tttccatttc catccaacac actgtataaa
    28921 gaaaaaggtg tattgtgtgt aaaattacat tttccaaaaa catctaattt ataaacacta
    28981 aaaaattcgt ttgacacaaa tgttgtgcat ttaaagtctg atgttgatac gattttatag
    29041 tcagtatcga aatttatatg aggaacattc gtaacatcta ttgatttttg aacatgaagt
    29101 tcacgcttat tacctgaatt gtcagttcta tcataatcat agactctata agtagtatct
    29161 gagttttgtt gagtttctaa aatcaatgtt cctttgcata tagcatgtat agtaccactt
    29221 ggaacataga aaaagtctcc cttttttatg ttaacctttc taagtagttt gtcccattca
    29281 ttattattta ccatatttac aaattcttta tgagattttg cattatgacc tattataatt
    29341 tctgcatcat cagaacaatc tattacatac caacactctg tcttacctaa ctctccattt
    29401 tcattttttt tagcatattc atcatttgga tgaacttgaa ctgataaatt atcatttgca
    29461 tccaatattt ttgtaagtaa aggaaactta tcaccaggtg tgtttccaaa taattctcta
    29521 tttttattcc acaattcaga tagtttttta cctttatatt ttccattttc tattaagcaa
    29581 tctccatttt tatgagagct tatagcccaa cattcaccag ttgttggcga atctatttca
    29641 taattaaatt tatctttaag tgcagtacca ccccatattc tatccataaa aataggtttt
    29701 aaaaataatg gttccataat tctgttcctc ctatgatatt aaatttatcc tacaaataat
    29761 tatatataaa tagattataa aatcaatagt aaaaaagttt tgtcccttga aatgacataa
    29821 agtataagga gttattaaat aagataaact atgatatata atataaagtt ctaaattgga
    29881 gtgataatta tggagttgtt taaggcagaa agcaaaaaat atgaaaaaga atttttaaaa
    29941 ttattggagc aatgggttag tataccttca ttttatgata gaaaaactgt atctaaagat
    30001 atgccttttg gaaaaggagt atatgatgca ttaaactggt ttgaaaatct aggtagagaa
    30061 aacaatttca aagtaaaaaa tatagataat catgctgttc aaattgaata tggaaatggt
    30121 aaagagtatg tagatatatt tggacattgt gatgttgtaa atccaggtga aggatgggat
    30181 agtgaaccat ttaaactaaa tattataggt gataaattag ttgctagagg tgtatctgat
    30241 aataaagggc ctatgatagt gaatttttta gcactaaaaa tgataaagga tttagatatt
    30301 aatttaaaaa gaaaggttag attaatagct gggggaaatg aagagagtgg atttaaatgt
    30361 ataaagcatt attatagcaa agagccatat ggtgtatgtg gatttactcc agatgctaaa
    30421 tttcctgtat taaatggaga aaaaggtgga gcaataataa agttaatttc aaatatagac
    30481 gataaatctt tatatataag tggtggaata gagtttaata caataccaga taaagtttat
    30541 ataaagaatg tagaaaaatt gggtaaagat aatatatgtt ttgatattaa caatatatcg
    30601 ataaattatg ataatggcaa ttatattgtg tatggaaaag gtggtcattc atctaaaccc
    30661 gaaaaatcaa taaatcctat attagctaca attaaacttt tgtcagaaaa tattgatgaa
    30721 aaatggacaa aagatttata taagttgata aatcaagata atataaatgg aaacttattt
    30781 ggtttaaata ttgaggggaa atgtgggatt ttatcaatgg tgccaacaat aataaatata
    30841 gtagatggaa aattagaagt agttttaagc gttagatatc cagaaatatt aaccattgaa
    30901 gatataataa aaaaatttaa tttgtatatg gagcaaaata atattaataa atttgagctt
    30961 attggggaaa atttaaagca agcaaattat atagatagaa attcaaaact tgtaagaagt
    31021 ttgcatgata tatatataaa gtattctgga gatttaaaaa atgatgttag agtaactagt
    31081 gcaggaagtt atgcttctga aatgaataat tcagtaatat ttggttgtga atttcctgat
    31141 ggtagctttg gcaatgtcca tagtgcgaat gaatttgcta gcttagatag atttataact
    31201 gcaataggta tatatgcaga ggcaataatt acattatgta ataaaatata aatacaaaat
    31261 gtcccttata tagacatatt atatatacaa ttaaaatttt acttgatata taattgaaat
    31321 caaagagaag gtgatacaat gataactaag aaacatgcaa taatagtaaa gagtttaagc
    31381 aataaagatg gatatatgac atcaaacgaa ttagctatca aattggatgt gtctactaaa
    31441 actattaaaa gatatatagc agatttaaat agtgttttaa gcaagtatga tttggtaata
    31501 gcttcttcta gaggtatagg atacaagtta agcggttcta aaaacaatat agccagagct
    31561 attaaagaag caaataaata tattgatggt tttttagatg actctgaaga gtcaagaatg
    31621 tcaaatataa tatgtatgct tattaataga aattatatga gtatagaagc aatggcagaa
    31681 gaattaaatc taagtatagc cgctataaat aaattgtcta gtaagcttaa aagaaaactt
    31741 gaaaagtatg acttagttat aaaatctaaa ccttactatg gaagctatat acatggtgaa
    31801 gaaattaata taaggcaatt aattactgac tatgcaataa aattagatga aaaaagtaaa
    31861 gtgaaggtgt ttttagatga cattagtgaa aacgatatac actgtataga aagtatttta
    31921 gaaaagcact taagagaaaa agatacaata atttcagata aagattttaa tcttttgctt
    31981 tcaaaaataa tcgtttctgt atttaggagt aagagaggtc atagtaacaa tataaactta
    32041 atggatacaa gttatagatt tcataactac tactttatag aaaatctaat gaaagaaata
    32101 tctgataaaa ttggatttaa acttattgaa gatgaagtaa tttatatttc aaattattct
    32161 ggtgtaatag cctataaagg tacacaagga agaaaaaaca caagtgaaat tgaggaacga
    32221 ataagtagtg ttataagtag tgcacttcaa gatatattcc ttatttcagg tagtgattat
    32281 acaaaagatg atgagtttat ggttgcaatc tctgaccata taaagagatt tttaaataga
    32341 gctagagcta atgtaaaatc aaataatcct ttgcttcatc aaataaaaga gaagtttcct
    32401 atagctttta atttagccgt gtttttatca aataaactag aaactgagtt taatttaaaa
    32461 cttgatgaag atgagcttgg atatatagct atccactttg ctgcttcaaa tgaaagaatg
    32521 aaaaaaaata ctagtaagaa aatttgtata gtttgtcatt atgggatagg aacaggacaa
    32581 cttatttctg aaaagctaaa acagaatata agtgatttaa gtgttgtggg tgtttatcca
    32641 gttagatatc tcgatatggc tataagtcaa gatgttgatt tgatagtatc taccgttgaa
    32701 ttaaaaggat atgaaaaacc tgtcttatat atagaaaata tatttgatga tagcttaatt
    32761 gaaaacgtaa acaaagcctt ttatgaaaag gaagaaagaa gaaagataat aagcaacatg
    32821 tttgatgaaa aagctttttt cagtataaag gctagtacta aagaagaggt cataatttca
    32881 ctttcaaata aactaaaaga aagagatttt atagaggaaa gttctataaa aagtataata
    32941 gatagagaaa atatttcatc aactgaaata ggaaatctag tagcaatacc ccacacaata
    33001 gtgaagggag ataaaaaatc tataatagga gttggaatac ttgaaaatcc aataatttgg
    33061 gataagcaag aggttcagct agtatttatg gtatttttta atactaaaga aaaacataat
    33121 ttctcgatat ttaaatacct ttataatttt ataaaagatg aaggcggagt aagaggaatt
    33181 attaaaatat gtgactttaa taaattaatg gcactgatag gtaattaagg aggaaattaa
    33241 taatgggaac aaacatattt aacaaagaat atgtattttt aaatgttgat gctaagtcaa
    33301 aggttgaagt tttaaaattt atatcaaaaa aagctaaaga cttaaacttg gcagaagatg
    33361 agagcttagt atatgaaggt ttaatggcta gagaagaaca atttactaca aatttaggag
    33421 aatctatagc aatacctcac actaaaaatg atgcaattga aaatccagca gtagtagtat
    33481 tgaagtttaa tgaagatgtt gtttggaatg aaggtgagga taaggttaaa ttagcaataa
    33541 gcttacttat gccaggaaaa agtaaagaga atattcatct taaattatta tcatctcttt
    33601 caagaaaatt aataaataaa gaatttaaag attctctttt aaaaagtgat aatgttgaag
    33661 aaatatctaa ctcaataaat gaagctttag gtttataatt aaacactaag gttataaaat
    33721 aaaaaaataa ttaactaaaa ataggaggaa tttgaaatga ataaaaaatt agtagcatta
    33781 tgtgcttgtc caatgggact agctcacact ttcatggcag cagaagcaat agagcaagca
    33841 gcaaaggcat taggttatga agcaaaagtt gaaactcaag gtgctgatgg tgtacaaaat
    33901 gagttaacaa gagatgatat attaggagca actatgataa tacatgcagt agcaataaca
    33961 ccagaaggta tggaaagatt tgatggttgt gaagtttatg aagttgaact acaagaagct
    34021 ataaaaaatg cagaaggtgt tataaaagaa atagaagaag atttaggaat ataataaatt
    34081 tattgtggag gaaatagaat ggcaattaag aaaaaagtta taaacagttc aggtgcttct
    34141 acaacaggag gaaataatgt aggaaaatct actccatcta gtccaactca atcaaaggga
    34201 aatggaaaat ggaaagaaat aagtaaacat ataatgacag gtatatcata tatgatacca
    34261 gttttagtaa tgggtggact tataggggcc ttatctcaat taataccata tgctatatta
    34321 ggacttgacc catctgtagg tatagttgat gctatgaact caggagaatt tacagggttc
    34381 aagcttagtc ttttaaatat agcacaatta atgtcaaatt tcggatttac tttgtttgga
    34441 tttgcgatac cactgtttgc agcattttgt gcaaactcta taggtggaaa aacagcttta
    34501 attgcaggat ttataggtgg atatatagct aataaacctg taggtgtacc acaattcgtt
    34561 gatggacaat ggactgaagt tgttccagtt gcatcaggat ttttaggtgc aatactaata
    34621 gcatttataa taggatattt tgtaaaatgg ttaaataaat ctataaaagt ttctcataac
    34681 tggttagctt ttaaaacaac atttttaata ccattaatag cgtcattagc ttgtatggta
    34741 ttgatgatat ttataataac tccatttggt ggattaatta atgaaagtat gaaaaacttc
    34801 ttaacagcag caggagcagc tggagaatat gtatatgcaa cagctttggc agcagctaca
    34861 gcattcgact taggaggacc aataaataaa gcagcaggat tcgttgcact tggtttaact
    34921 acagagaatg tacttccaat aacagcaaga acaatagcta tagttgttcc tccaattgga
    34981 ttaggattaa caacattatt agataaaaga ttagtaggaa gaagagtata tgatagacaa
    35041 ttctatcaag cgggaaaaac ttctatattc ttatcattta tgggtatatc tgaaggagca
    35101 ataccatttg cacttgagag accaggtttt gttatacctt taaacatagt tggaagtgta
    35161 ataggagcta ttacaggtat aattctagga gcaattcaat ggttcccaga gtcagctata
    35221 tgggcatggc ctctagtaga taacttattt ggatatataa taggtatagc agttggtgct
    35281 atattcatag cagtaggaaa tatattctat agaaataaat taataaaaga tggtaaactt
    35341 gttgtagatt atatcgacta gtatttaatt tttactatct ataaataact ttggctggta
    35401 atatggtttt aatcaatatt accagcctta cctatatgat taattaaagg cggtggagat
    35461 aagatatgga taagatagaa aaagtaagag agtattttag agaatatgat atagatggat
    35521 ttcttataaa tagtcctaca aacaagtttt atgttggaaa tttatttagc tcttcaggtt
    35581 atgtttttat aacgaaagaa tcacaatata taatagtaga ttttagatat tttgaagaaa
    35641 ttaaaagaaa atctagtttg tttaatgtag tattaatgga caaaactaga actcattttg
    35701 atataattaa tgatatttgt agagagcaga atataaagga aattggattt gagggaaatg
    35761 aagtatcttt tgatttatat agaagtatga gtaataagtt aagtgcaacc ttaaaatcag
    35821 ttgatttatc tacattaagg gaaacaaaaa atgaagacga aataaaatat ataaaaaaag
    35881 cttgtgaaat agttgatgct acattttatc atatagtaga ctttataaag gttggtatga
    35941 ctgaaaagca agttgaaaat gaaattgtta gaattataaa agctttaggt ggtcaaaaag
    36001 aatctttcga tacaatagtt gcatctgggc ttagaggagc attacctcat ggaaaagcaa
    36061 gtgaaaaagt tatagagtat ggagattttg ttacttttga ctttggtgct aagtataata
    36121 attattgttc agatattacc agaaccattt gtatgggtac tataaataaa gagttagaag
    36181 aaatatataa tatagtaaga aaagctaatg aagagtgtat aagggtttta agaccgggaa
    36241 tgactactgg agagatagat aaagttgcaa gagacataat tggttcatat ggatatgcca
    36301 ataattttgg tcataatctg ggtcatggtg taggaattat ggttcatgaa tatcctgcat
    36361 tagctcctga atcaaatgaa gtattaaaag aaggaatgat tgtaactata gagcctggta
    36421 tatatgttcc aagtcttgga ggcgtaagaa tagaagatga tgtacttata acacaagatg
    36481 gatgtatgag attgactaca tctactaagg atttaatagt tgtaagctaa aaataaatta
    36541 gataaatatt ttataacaat aagaaaagaa gaggtaaatt taaatgtata attttgatga
    36601 taaaccagat agagtaagtg aaaagtgtag aaaatgggat ttaaatatta taagagataa
    36661 atttggagat attagagaag attttgtacc aatgtggatt gctgatatgg attttaaaat
    36721 accaacagaa atagaaaaca aatttattga agctgtaaga agaggtgtat ttggatatac
    36781 atactgttat gatgaatttt atgattcagt tattggttgg caaaaaaata tgcatgaggt
    36841 aaatgtagaa aaagaatgga ttacattaac ttatggaact gtatcaacac ttcattatgt
    36901 agtacaagct ttttgtaaga aaggtgatag tataatatta aacacaccag tttatgaccc
    36961 ctttgaatca tcagcaaaaa aacagggtgt aaatgtaatt tgtaatacac tagatgttgt
    37021 aaatgataga tattatataa attttgataa attagaagtt caaattaaag aaaataagcc
    37081 taaattaatg atgttttgta caccacataa tccatccgga aggatatgga caattgaaga
    37141 aatgacaaga gtagcaacta tatgtaaaga aaataatgtt attttggttg cagatgaagt
    37201 acatgcagag catattcatt atggtaaatt taattcaata cttaagattg gaaaagagct
    37261 tttagaaaat gttattctac tgacatcacc aaataaagga tttaatcttg gtggattaaa
    37321 gacttcttat tcaatagtta taaataagga tataagggac aaatttagaa ataaattaaa
    37381 gcaaaattct ataacttctc caaatgtgtt tggaataata ggattgataa ccgcttataa
    37441 tgaatgtcat gagtggttaa gtggtgtaaa tgaatatata aaatcaaatt atgaactttt
    37501 agaaacttgg gtaaataaat ataataagat aaaattgatg aaaatggaat catcttactt
    37561 agcttggatg gatataagtg gattaggtat tagtgcaagt gagtttacag ataaattggc
    37621 tatagataca ggagtattat tagaagatgg aagtcatttt gtaaaagatg gtgagaagta
    37681 tgttagaata aatttaggaa ctcaaaagga aaatgtaatt gaagccttaa atagaatgga
    37741 tttattttta aagtctttat aaaaatttgg ttgaattagt attttatata aatttaaact
    37801 attaatatgg tatatacata agtagaattt gttttagatt acttaagtat ataccatatt
    37861 ttatataaaa attaaatttg cattagtcat gtgataacta tttaaattca tatgtatttt
    37921 gtatgtataa tagatataat tattatttaa acttattgtt tatttaattt ttcaatagaa
    37981 aaagatttat ctgtaagttt aaaattatct tttataccct tagttaaata tactttctta
    38041 tccttagtta tgaatatagc atctacatta tcaattttat taattaaatc catacctttt
    38101 tcaagaccaa gtccaaatgt agaagtggat aaggcatcac aattaataga tttatcagag
    38161 attattgtaa cactacttaa attgttttca aaaggatacc ctgtaaatgg atttaacata
    38221 tgatgatata tttttccgtc tttttcgata aatctttcat aaattccaga agtaacaaca
    38281 gacttatttg tagtttctat gtttcctatg gattcaccat ttttactagt tgggtcttga
    38341 atgcctattt taaaaggttt atcattttta ccatcttcta aagtaaatat atttcctcct
    38401 aagtttacta aacctttttt tacatcctct gattttaaat aggctacaat tttatcagca
    38461 gcatatcctt tagctatggc acctaaatca attttcatat tttctttggt taattttata
    38521 gatttatttt tttcatccaa tatgatgttc ttataatcaa taagaggcag aagtttttgt
    38581 atctcagaat cacttggaac tttagcttta tctgttccaa tagcccataa atttgataat
    38641 ggaccaattg ttatgtcaaa atatccatct gataatttgg aatattgtat agcttctttt
    38701 acaacgaaaa atgtatcatc agaaactctg acaaattttt taccagcatt atcatttatt
    38761 ttagaaacat cacttcctgg tatatgagtg ctcattttgt tgtcaatata tcttaaaatt
    38821 gaatcacatt catttaagat tttatcactt ttggattctt ttacattaaa tacagtaact
    38881 tcgtttactg taccaaggta gtagctagtt ttactatatt tagtattctg gcttgaactc
    38941 ctaaaaaatg aaaataaaat taatgctaaa atcaatatca caaaaataaa tgtgattttt
    39001 ttcttattca tggtatattc ctcctatgaa attgtgttat tattttatta taacataatt
    39061 tcataggagg acaaaaaatg aagaaaaaag acattcttct tattttaggc attttggttg
    39121 ttattacagc atgttatggg ataataaatg ttataaattc taaaaatgct ggaaatattg
    39181 agatttatgt agataataaa ttgtataaaa ctgtttcaat aaatgccaaa gaagaattta
    39241 aaatagagaa tagagggggg tataacatag taaagattca tgataaaggg gttgagatag
    39301 tagatgcttc atgccctgat aaggtttgcg tacatactgg atttataaac aagccaagtc
    39361 aaagcatagt ttgtatacct aatagagtga gcataaaaat aaatacaaat gaaaagaatg
    39421 ataatcaaga agatataatt tctaaataaa ataataaaaa taattgaaag gaattggtga
    39481 taattatggt taacttagga aacgattggg atgaattatt gaaagaagaa tttgaaaaag
    39541 attactactt aaacttaaga aaatttctta tagaagaata taaaacacgc caaattttcc
    39601 caaatatgca caatatatat gaagctttaa aacacacttc atacaaagac acaaaagtct
    39661 taatattagg acaagaccct tatcatggag ataatcaagc tcatggttta gctttttcag
    39721 ttcaaccaca agtgaaaact ccaccatctt tattaaatat gtataaagaa ttaaaagatg
    39781 atttaggttg ttttatacct aataatggat atttaatgcc ttgggcagac caaggagtgt
    39841 tacttttaaa tactgctctt actgttagag cgcatgaagc taattctcat aagaacaaag
    39901 gatgggaaat tttcactgat agagtaatat ctattttaag tgagcgtgaa gacccagtta
    39961 tttttgtact atggggaagt aatgcacgta aaaaagtaga gttgattgat acaagtaaac
    40021 attatatttt ggaagcacct catccaagcc cattgtcagc aagtaaaggc ttttttggat
    40081 gtaaacactt ctctaagata aatgaaattt tgaaaaagct aggaaaagaa cctattaatt
    40141 ggcagataga aaatatataa aagtaaaagg taacaaaatg ataacaaaac aacaataaac
    40201 aatgacattg ttgtaactaa tagaaatatg cttaaatggt tgaaaaaact atgtatgcat
    40261 atttctattt ttttgtcaag ttgacaactc ttgaaaaaat agttacaatt tagttacaca
    40321 aaaaacacaa ataaaaaaag aaacttacaa agcagaattt tatgaagcaa aatatatagt
    40381 gtaaaaaatc ttagggagga aattttatat gaattttaaa aaattgagta atgctaaagt
    40441 ctcggtaatg gcagttgttt tatcagttgg aatattatcg ggatactctg cgcttaataa
    40501 acaagtaaca ttagtagtaa ggggagaaga aagaactata tcaacattta gttctaatgt
    40561 aggagacctt ttagaatctc aaaacattag ctatgatgca aatgatatag taactttaga
    40621 tgaaaataca aagttatcta atggagataa aatagaagta attgatgtaa aggaaaaaac
    40681 agttgtagaa actaaagaca ttccatttga agttacagtt gttgaagatg gctctttatt
    40741 aaagggtgat tctaaggtta aagaagaagg aaagtctggt aaaagtgaat taatatataa
    40801 agaaacttat cacaatggaa agaaagtaga aaaggaattt gtgaaaaagg ttgttaaagc
    40861 tgagccagta aataaggttg taagcaaagg gacaaaggta gaaatgcaag tagcctcatc
    40921 aaggggagaa agttcaagaa gaatggcttc atcatcatct agtagcagta gtagtaacaa
    40981 tggtaaaaat atgagagtgg tagcaactgc atatactggt cacagtataa ctgcaacagg
    41041 aacaaaacct aagtggggaa caatagctgt agaccctaag gttataccat atggaactaa
    41101 agtttatata cctcaatttg acatggtgtt tactgcagaa gactgtggtg gagcaataaa
    41161 aggaaataaa attgatatct acatgaatga ttcaaaaaca gtttataact ggggaagaaa
    41221 aactatagat atacgtatat taaaatagtt aaataattta tatttttact ggaaattata
    41281 ttttgattat atagagaaga aactctttat agattctaaa aatataattt ccagtttttt
    41341 attttggata tgtaataaaa caggtaaatt ttaaccatgt atagataaaa gctatttaaa
    41401 ttataattta ctatcatata aatctataaa aattgttgca aagagtcaaa atatatgata
    41461 ttatagattt cgttgagaag gatttcatta tgggagtgga tgggtgccgg tgtgccctct
    41521 agtcttcaaa actagtatga ggggttaaga gcctcttagg tgggttcgat tcccacgcat
    41581 tcccgccaat atgtaaaagg tatcttttaa ttaaaagata cctttttaaa tttattttaa
    41641 gataatttat ttttaataat atataatgtt ttgtattata taatgtaaat tttctaatac
    41701 tattatatat ttagataaaa atctaggagt gtggaaagat ggaaaataat tttacaacga
    41761 gaactagttt tctagttgga gatgatggga taaaaaaact taataattca aatataatag
    41821 tatttggagt tggaggagtt ggtagtttta ctgttgaagc tttagcaaga gctggagtag
    41881 gcaatattac tattgtagat tttgatgatg tagatataac caatataaat agacaaatac
    41941 cagccctaca ttcaactgta ggaagataca aagttgatgt catggaagaa agaatattag
    42001 atataaatcc taatatcaat ataaaaaaaa taaggagtct ttataataaa gatactagtg
    42061 acgaaatact aactgaaaga tatgattatg ttgtggatgc gatagacatg gtaagttcca
    42121 aaatacatct aattgaaact tgtgaaaaaa aaggattgaa aataataagt tctatgggta
    42181 tgggaaataa attagaccca actaaaatag tcgttacaga tatacacaaa acaagtactt
    42241 gtcctctagc taaagttatg aggaaagaac ttagggatag aggtatcaaa aagttaaaag
    42301 tagtatattc tactgaacaa ccaatagaac ttaagaagaa agtaatgaat ggtagaaaag
    42361 taacacctgg tagtgtatca tttgtcccat ctgtaggagg tttaataatc gcatctgtaa
    42421 tagtaaatga actattagga caataagttt taaatatttt aatttataaa ttttatatac
    42481 aaatttgaag gctagaagca tgaatacaaa gcaattttat attcatactt ttagcctaat
    42541 tattttatat taccttattt tatgtagttg tagttttatt ttttagatta tgtatctatt
    42601 tcataattat attttgtaaa tataatttct ccatcactat aaaaaacaat atctcctatt
    42661 ctatctgttc tataaattga tacatggttt tgttttagat tattaataac ctccctatgt
    42721 ggatgaccat attgattttt atatccacat gatattgcag ctatatctgg actaattttt
    42781 tttataaatt ctaaagatga agaagaatta cttccatgat gacctatttt tataaaatta
    42841 atattattta atttaaaaga atgtaaaatt tcttttttat tttcttcttc agcatcaccc
    42901 ataaataaaa aagaattatc attaaaagtt aatttaaaaa ctatagaatt taaattagat
    42961 tcttcttgta tatatgatgg acttaataca tatatattta tattgttatc tatgtttaaa
    43021 acatcatttt tatagagatg ctgaatagat aagtttttat ccgtacaaga atttattaga
    43081 ttttgataag cctcactatc agttgattgt tcaggcatat atatggagtt tacattaaat
    43141 ttttttataa tattatcaag acttcctatg tggtctgaat ctggatgagt tgctattata
    43201 atatcaatag tttttattct tttttgtcta agataactaa taattatatt ttcgctatct
    43261 tcatcacctc catcaattaa tatattctta tttgtgggtg tttgaactaa aatactatca
    43321 ccttgtccaa catcaatcat atgtatagat agtagagatt ttttgtcaca gccgattaaa
    43381 agtgatatta taataagtat tgataaaaaa attttatttc tcaataaaaa atcactccat
    43441 tcattacatg tttatataaa tttatgatgg gtaatataag atatatatga cttattatat
    43501 tttatatttt aaacaatata aatgaaatta ataccataat aaaattggag ttttttatat
    43561 atacaaaata aaatttttaa aattaagcaa taaaaaaggt aggaggattt tatgtttttc
    43621 aaagatattg aactaaattc aaaaaaagag ttagactcat attttgattt agtagattat
    43681 gaagcttgtg agtactgttt tagtacttta tatatgtggc aacatgttta taagacagga
    43741 tattatatag gtgaagattt tgccgtttta gttggggaat acgaaggaga tagcttctca
    43801 atattaccac ttgctaaaaa agataaactt ccagaagttg tagattttgt ccttgaatat
    43861 ttttctaaaa ataataaaaa aatatactta agaggtatta ctactgaagt agtagagttt
    43921 ttaaaagaaa aatatccagg tagatttgag tatatagaag aaagagattt atttgactat
    43981 atttatgatg cagaaagttt aagaactcta gctggtaaaa agaatcaaaa gaagagaaac
    44041 catataaact atttcttaaa agagtatgca ggtagatatg aagctaaatt attagataaa
    44101 gaaaactttg atgagtgttt agtactaatg aaggaatggg aaagtaataa ggaagaaaat
    44161 aatgaatttg atgaaagtat ggatgatgaa ttaataggta tcaaaaagat atttaaccat
    44221 tatgacatat taaaagataa ggtaaaagtg tttggtgttt atgtagatgg aaaattagaa
    44281 gcttttagta taggagagct tttaaatcca aatatggcat tgattcatat agaaaaagct
    44341 aatcccgata taagaggtct gtatccattt ataaatcaac aatttttggt aagtgaattt
    44401 aaggacgttg agtttgtaaa tagagaagaa gatttaggta ttgaaggatt aagaaaagct
    44461 aaactttctt atcatccttg cagatttgtt gaaaagtaca gtgttaggga ggcttaatag
    44521 actatatgga gattaggtat gctaaagaag aagagataga aagtataaaa gatatttgga
    44581 gttattgttt taacgatacg gagagtttta tgaagtacta ttttaatgat aaatataaat
    44641 ctgaaaatac tgtagtagct ttagatgaag gaaaaattat ttcttctctt cagctaaatc
    44701 agtataagtt attactaaat agcaaggtat ataatacatc atatgtggta ggagtttcta
    44761 cacttccaga gggaagagga gctggatata tgaacaaagt aatgaaattt actttaaacg
    44821 aattgtataa aaaagggcaa ttagtttcta tattgatgcc tattgactat agactttata
    44881 gaagatttgg atatgagcat tgttacgacc agattgaata tactattaac acagatgatt
    44941 taaaaaattt taagtcaagt ggaaaaatga taaagtctaa tttatcacaa attgatgatt
    45001 tgatacaaat agatagaact tttttaaatg aggttaatgg taatgtgtta aaagatgaac
    45061 attattatga aaacttattt aaagagattc aaagtgaaga tggattttta tacattcatg
    45121 aaggaaatga aaaagatgga tatatagttt attttcttca ggaagataaa atgtttgtca
    45181 gagagttatt ttataaaaat atagatgccc ttaaatcaat gcttaaattt atatataatc
    45241 acaatactca atgtaagata gttactatat ctactcctac aatagataag ataaggttta
    45301 tattagacaa ccctaaagat agtgatataa aaataaaacc ttttatgatg ggaagagtta
    45361 taaatgtaaa gaagtttatt gaagatatag atattgagaa tgatattaat agctcattta
    45421 atttattaat agaagacaag tttatagatg aaaataatgg tctatttaaa atttctatac
    45481 agaataagaa ggtatctgta gagcagttag ataaaaaagg tgcagaaaag cctcaagaag
    45541 attttgatat taaattagat ataaatacct taacacagtt atcattttct tatatagatg
    45601 taaatgaagc tattttctta aatgatataa aagatgtttc agaagaaaca ctagaaacac
    45661 ttaattgtat tttttctaaa aaaaataact atataaatga atatatatag gtagagtacg
    45721 ttaaaagatt ttaaaaatct tttgacgtat ttttttgttt agataacaat ttatcttgtt
    45781 taaaaatttt ctatttgaaa ataatctaaa taatatactt ttatatggga gtgattataa
    45841 ttcaaataag aagaccatta ttaattatat taatgtttgt ggtagctata tcatttatca
    45901 ttacaaataa cacaaaaaac gacgaagaac ttaatgataa gataataact atacaaggag
    45961 ttgtcaaagg aaaaattgaa aagaaaagat acaatcagta caaggtaggg gtttttctaa
    46021 taaatgatta tacaaaaaat aaaaatttga agattggtca gaaagttaat attacaggta
    46081 aattcaaaag tttagataaa atgaagtatg atgattttga ttatggaagg tatataaaaa
    46141 gtactggata taaaggtata gtgtatataa ataactataa aattattgat aaaaataaac
    46201 tttactcttt aataggggaa ataaagtttt atattagtaa aacttatagg tacttatata
    46261 agaaaaactc agattttata aattctatac tattagcaga agttgaaaat ttgactgagg
    46321 aacaaaaaga aatttttacc agaactggaa ctagtcatgt aatatctata tcaggtcttc
    46381 atacaggaat attatgtgta attatatcct ttctattaag aggtataaat aaattgtata
    46441 aattattaat actgtcgatt tttataactt tatattgtat aatggtaggt gcgtctccat
    46501 ccataattag gtctatagca tttgttatga ttttttattt atcaatattt attgatagaa
    46561 agaaagatgg aatatcggca ttgtctctaa ttgggataat tttaattatg aataacccct
    46621 atgttatata taatgtaagt tttcaattgt cttttttagc tacactttct atattaatat
    46681 tctataataa aataaatagt attataaaat taagtatggt atcattgaca atatcatcaa
    46741 atatattaac tttacctata atttattata catttaaagg tataccattg ctttcaatta
    46801 taggaaattt aattatagta ccatttgtgg gagtaataat gtatttaagt attgcaagtt
    46861 taatcgtatt taaagtaagt gtagtaatag ctaaaattat atcttttttt aatagtacat
    46921 tgatagaaag catatttttt ttactagaaa aaatcagcaa tttaagtttt gcatacatta
    46981 atatagaaaa tcctaaattt tatattgttg ttatttatta cataggagtg tttttttaca
    47041 tattttacat agaaggaaaa gagataaagg agcaagagaa tgaattacaa ggatattata
    47101 aggaatgtaa aagagaaaaa ctttgaaaaa atgtatcttt tttatggaag agagtattat
    47161 ttaattgaga atgcaataaa agcatttaaa gatagtctaa acgagggaat gcttgatttt
    47221 aatttagata taatagatgg gaaggaaata gtcttaaatc agcttataag ctctatagaa
    47281 acacttccat ttatggatga taggaagata gtaataataa aagactttga actattaaaa
    47341 ggaaagaaaa agaattttac agatagtgat gagaaatact taatagagca tttagacaat
    47401 attccagaca ccacaactat agtttttgtt gtatatggag atgtagacaa aagaaaatca
    47461 ttagttaaga aaataggaaa caatggaatt gtttttgatt gtgataagct ttctgatatg
    47521 gatttgttta aatggataaa aaaatctttt gctttaaatg atgttataat agataattct
    47581 caaatcatgt attttattga acaagaagga tacagagata agagtagtga aaaaacatta
    47641 tctgatttag aaaatgaaat aaataaaata agttcatttg ttggtaaagg gaataatgta
    47701 accaatgatg taattgataa attatctcaa aaaaaagttg agaatgatat attcaaatta
    47761 atcgattata ttggagaaca aaatgcttct aatgcaatga aaatattaaa tgatatgata
    47821 caagaaggcg aatctgtatt aggtatattt tctatgatag caagacaatt taaaataatt
    47881 atgcaagtaa gacagttaca acttgatgga tattcaacaa aacttatagc tgataaatta
    47941 aaaatgcatc aatttgttgt aggaaaagca ttaaagcaaa ctaaaaattt ttctgatgat
    48001 ataattgtgg aaatattaaa ctatatatta gaaagtgatt acaaaataaa gacaggtctt
    48061 ataagagata ctttagcagt tgaaatgttg gttagtagat actgtaaaag agaagcaatt
    48121 taaaaaatct atatattaat aaaaaataaa tagcaagata tgttatagtt cagagtagat
    48181 gtaagctaaa ttaagtttga tatacaatca actataatat gtctaactat ttatttttta
    48241 ttgtataaat ttacaaaata aaaaacccct acataggggt tattatatat aagaaatata
    48301 aactggtaat taagcgttca taccgtttaa tttttgagct aatttagcta cttttctagc
    48361 tgcagcattc ttatgtatag ttcctttaga agctacttgg tatattcttt tttgagcgta
    48421 ttggaactta gcaacagcat cctctctgtt tccagctgca acagcatctt cgaatcttct
    48481 tattgcagtt tttatttgag attttctaac tctatttaaa gcagttttct tttcgataac
    48541 acttattctt ttcttagctg attttatatt tgccaccgtg ttcacctccc tgtatttttt
    48601 tatcatattc atcgtcaaca tattagattt taacagaaat aaatctaaaa atcaaggatt
    48661 attatttata tattttaata atgtttttta ttttgatttt ttagactgta aattgtgtat
    48721 aaataatttg caatatcttg tttttaaatt ggtatatttt gtgttttaaa tattttgaca
    48781 tatataaatt aatattttat ttttgaaaca aa
//
LOCUS       DAMJXI010000025        48430 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.026, whole genome shotgun sequence.
ACCESSION   DAMJXI010000025 DAMJXI010000000
VERSION     DAMJXI010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48430
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.026"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            206..1519
                     /locus_tag="PC465_001833"
     CDS             206..1519
                     /locus_tag="PC465_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2649131.1"
                     /translation="MHTQLQKTIGLSAALSTVVGMVIGSGVFFKPQAIYTTTNGAPGL
                     GIIAWLLGGFITITAGLTATEISAAIPKTGGMMIYIEEIYGEKLGFLTGWMQTVLFFP
                     GTSAALGVIFAQQASELLGMSPNNMANVLPIAIGVILFLALLNIIGSSLGGKVQTVAT
                     IGKMIPLILIIVFGFIKGQSSEVLNPFVGDGVNASNALGQVLIATLFAYDGWINVGAI
                     SGEMKSPEKDLPRAIVGGLSLVMAVYIIINIAYLWVVPASELATVTSPATLVATRLFG
                     NIGGKVITVGILISVFGTLNGYLLTGSRIPYTLAEMGTLPASKTLLKVNSGGSPVNSI
                     LLITVLACVYALSGQFNLLTDLTIFSIWVFYVLTFIGVMRLRRQKPDLHRPYKVPLYP
                     IIPIIAILGGLFVIINQILTSTVISLGGIFITLLGLPVYYYMKKR"
     gene            1691..2866
                     /locus_tag="PC465_001834"
     CDS             1691..2866
                     /locus_tag="PC465_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HDF2649132.1"
                     /translation="MLGLYVHIPFCVKKCKYCDFNSYKMDIDSKKRYIEDLKIEMELY
                     SNKLYKDNKYKNKECCSLNKNDKITSIFVGGGTPSILTSDEIREVFISIKEMFDIDEN
                     AEITIECNPGTLTLEKLKTMKEIGINRLSIGLQAIQEKHLNFIGRIHTYEEFEKNYKD
                     ALSVGFKNINVDLMYSLPNQTLCDWKETLEKVVHLNPTHISAYSLILEEGTELYNMYE
                     SNKFELIDENVDIEMYEYTINYLKSKGYNQYEISNYSKEGYNCEHNILYWECEHYIGI
                     GAGASGYINENRYNNVESLEDYHLSLVKREKPIQENEILSEKDMIEEKIFMGLRMNKG
                     IKFEDFKKKFGIDFREKYNKQIEMLLARKLINQSFEGIQLTQKGREISNSVFIEFME"
     gene            2969..3988
                     /gene="hrcA"
                     /locus_tag="PC465_001835"
     CDS             2969..3988
                     /gene="hrcA"
                     /locus_tag="PC465_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcription repressor HrcA"
                     /protein_id="HDF2649133.1"
                     /translation="MELNERKLNILKAIVKDYIETAEAIGSRTISKRHDLGVSAATIR
                     NEMADLEELGYLIQPHTSAGRVPSEKGYKLYVNSLMSKSELDDNDKILIEQCMNHNIN
                     HIKELIHETSKLLSQLTNYTTVAVTKSLINQSVIKHIQLVAMNDNNILLIVVTDKGDL
                     KKANLTTNVYLDQSKLNLISDNLTRKLLGKSITDLDDNLIAFIKYEISEYSGLIDELL
                     NALNSNMKEEDFSLSLNGATNIFSYPEFNDVLKAKSFLNMLEKKETIADIIKSKGIQK
                     DNLNIIIGSDNDCELAQDCSIVTATYNVDRDLVGRISFIGPTRMDYARIYSIINYMSL
                     LINRK"
     gene            4018..4638
                     /gene="grpE"
                     /locus_tag="PC465_001836"
     CDS             4018..4638
                     /gene="grpE"
                     /locus_tag="PC465_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HDF2649134.1"
                     /translation="MDKKNEQQEVREENDTSINQESETQVELEEEVVNEECETSSEKT
                     DEKEVDDENVTDINSKLAEKKLQDELDELNDKYQRLQAEYANYRRRTQQEKETIGVFA
                     NEKIITELIPVIDSMERALDACEDKEDTMYKGISLVHKQLIDTLVKFGVEEIEAESKE
                     FDPNLHLAVMQESVDGVEANQIVMVLQKGYKLGTKVVRPSMVKVSC"
     gene            4730..6577
                     /gene="dnaK"
                     /locus_tag="PC465_001837"
     CDS             4730..6577
                     /gene="dnaK"
                     /locus_tag="PC465_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HDF2649135.1"
                     /translation="MGKIIGIDLGTTNSCVAVLEGGEAQIIANSEGMRTTPSVVAFTK
                     DGERIVGEPAKRQAVTNADKTITSIKTHMGTDYKVNIDGKSYTPQEISAIILQKLKSD
                     AESYLGQTVTEAVITVPAYFTDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKL
                     DQEKKILVFDLGGGTFDVSILEIGDGTFEVLATAGNNRLGGDDFDQIVIDYLAEEFKK
                     AEGVDLRNDKMALQRLKEAAEKAKKELSSTMSSNINLPFITATAEGPKHLNIDLSRAK
                     FEELTRGLVEKTMEPTKTALQDAGLSTGDIDDVLLVGGSTRIPAVQEAVKKFIGKEPH
                     KGINPDECVAAGASIQAGVLAGDVKDLLLLDVTPLSLGIETMGNVMTKIIERNTTIPT
                     KKSQIFSTAADNQTAVDIHVLQGERSMAYDNTTLGRFQLTDIPPAQRGIPQIEVTFDI
                     DANGIVNVSAKDLGTGKEQKITITSNTNLSEAEIEQKIKEAEMNAEADKQKKEKIEAF
                     NQAESTIYQTEKTLNELGDKISSGEKEDIEKAIADLKAVKDNQDATAEELKKATDEVM
                     TKFQKVSQEMYQKAAQEQQAAQGAEQAQDNGPKDDNVVDADFKEVDEDK"
     gene            6788..7942
                     /gene="dnaJ"
                     /locus_tag="PC465_001838"
     CDS             6788..7942
                     /gene="dnaJ"
                     /locus_tag="PC465_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HDF2649136.1"
                     /translation="MSTKRDYYEVLGISKGAEAQEIKKAYRKLAMKYHPDRNPGDKEA
                     EEKFKEINEAYEVLSDDTKRKTYDQFGHDGLNGQGGFGGQGGFGGQGFGGFEDMFGDI
                     FGDMFGGSFGGGRARRRGPQRGADIRQSVTISFEEAAFGKKMSIKVNRSEECEECNGT
                     GAKPGTSKKTCSTCNGTGQVRTVQRTPFGNIASSRPCSACNGTGEVIESPCSKCHGTG
                     NTRKVKTIEVDIPAGIDDGQMIKLSGQGEVGEKGAPRGDLYIVVNVKSHPLFTRDGND
                     IYFEMPITFVQATLGDEIEVPTLDGKVKYSVPEGTQTGTVFRLKEKGIPRIRGNSRGD
                     QYVKVVVEIPKKLNDKQKELLREFAKECGSNVHEKKKTFGQKIEDMFKKK"
     gene            8908..9843
                     /locus_tag="PC465_001839"
     CDS             8908..9843
                     /locus_tag="PC465_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDF2649137.1"
                     /translation="MYYIGVDIGGTGIQAGVVDNYGKIIFRSECKTVIEKGFEGILND
                     IKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKRRFPD
                     VEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEI
                     GHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNA
                     KMVFDAYRENDLVAIKVINRFKEYLAKTFANTINSLDPEIISIGGGISKSSDIILDGI
                     EDLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL"
     gene            9879..11252
                     /locus_tag="PC465_001840"
     CDS             9879..11252
                     /locus_tag="PC465_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2649138.1"
                     /translation="MGKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISF
                     TTVSWIVSAFYLANAIAQPVSGKIGDLIGRKVLFLSGLMLVILSASIVPLVQSFFILI
                     FIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLG
                     GWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMI
                     FILLFLLSMKESFNLEQLVFGIILMCLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQF
                     IILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGKWIDKSGTRF
                     PLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDS
                     IGTASGLFQTSRYLGSILATVLLGMVFEVNITSEQFQILGYVMVVLGTISFLLNFILK
                     KELRKVE"
     gene            complement(11440..12207)
                     /locus_tag="PC465_001841"
     CDS             complement(11440..12207)
                     /locus_tag="PC465_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2649139.1"
                     /translation="MEELKDFLERQLNKKINIYPYENQKLDASSHLVTFNNAIYVIDF
                     LDKNNLDNLKGNFYLIYQSHIDFEYLKNIFYNLFEDINIIQHNGFFIVNSKYNLDINV
                     TTQNIIETETYQSTYIFYLGKLDSKADFDFRLQLCSDLLPHIIKDNAENKFLNLFDLI
                     RYKTLDLINEDNILNKLIDFNKIKSIDEELLYTGIKFINNDLNISKTSTSMFLHRNTL
                     VYRLEKINEILGFDLKNFENAMIFYLSVKSYFLYKKI"
     gene            complement(12237..13346)
                     /gene="ugpC"
                     /locus_tag="PC465_001842"
     CDS             complement(12237..13346)
                     /gene="ugpC"
                     /locus_tag="PC465_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003242648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HDF2649140.1"
                     /translation="MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKS
                     TTLRMIAGLEEISEGELYIGDKLVNDIEPKDRDIAMVFQNYALYPHLSVYENMAFALK
                     LRKLPKDEIDKKVKEAAKILDLLPLLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDE
                     PLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGVVQQIAT
                     PQDVYDYPANIFVAGFIGAPQMNFIDVILIEENDEIYAQNEHIKLKLNKEKHYDLIKD
                     NYINNEVVIGIRPEDIHVEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITI
                     RFDSKNRINVGDDLTLSVDNSRVHIFDKETTLAIR"
     gene            13604..14341
                     /gene="cas6"
                     /locus_tag="PC465_001843"
     CDS             13604..14341
                     /gene="cas6"
                     /locus_tag="PC465_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HDF2649141.1"
                     /translation="MSRISIFMESCNGKFPNENSMLSVSFIKNILNAENKDFAKNIFN
                     YGEERKNNKQIKDINTAIYIPNLIRSKNELLVDGDIIFNISFYNYSMFSKLYNGILKV
                     KELEYKGYRFKIKNIKIHKEHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLN
                     YIANLTLESVRGSGLRKPLEFIPLNFKKRVLKEKIRGFKVREFYYINAYAGTFFLKGD
                     MEDLNALYKMGIGYRRTENAGMVDILK"
     gene            14346..15821
                     /locus_tag="PC465_001844"
     CDS             14346..15821
                     /locus_tag="PC465_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649142.1"
                     /translation="MREIKAKFYRSGDIVRDIGIVYFYELLMDLKNELEKNDYKLKFT
                     CELNRNYLSLESAEYIDPKYISDYILENQLFKVFKNGKKETLEKIFSNIDNLTYVNFI
                     EELDKSSATAKQKEDIKKDFKNRRFPYVRNSGKYGLNTSLENMETNVKRIVDTVIKSN
                     IEIDEIDKLDLTQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKR
                     SGQVESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKS
                     FYKKLLHEKISSIRLYRFDIVKNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREP
                     VNTKNLGKKMIDNGNLSNLKELLLDNISFLKQSTGTSREMDFVSSSYNIGLYIKLCWI
                     VDGGEEYKMKNYMESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRTQLFQT
                     IMHVLVSNGILIGEGFVEGLMQSSELELNTNVGLFIQEIMK"
     gene            15841..16854
                     /locus_tag="PC465_001845"
     CDS             15841..16854
                     /locus_tag="PC465_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DevR family CRISPR-associated autoregulator"
                     /protein_id="HDF2649143.1"
                     /translation="MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYREKIHA
                     KTSIATITYDLRRMLHQEYGWNLSNIVFGKKGNIYPSIKKNVGCVDENGLETDVFGYL
                     IPLKDKGSISKASPLRIIPFRSLNPYKGSTQLITNRGFLSSEFGRKYYDEKEENEVPR
                     DENFPTSQALAIEETLSDYYVYTITLELDRIGVVEVEDGKLLLPEERKFMSKELREKA
                     VKDILDAITVFTRNIKHSSVLLKPLAVMGGAFDKVVPFFWDDVDYNADSGEINLEGVI
                     ETIESYSLKESNTILAINDRLKISNKKELNKFNLSKYPVKEIKNLADRLEIGEDNMWY
                     LKE"
     gene            16870..17667
                     /gene="cas5"
                     /locus_tag="PC465_001846"
     CDS             16870..17667
                     /gene="cas5"
                     /locus_tag="PC465_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HDF2649144.1"
                     /translation="MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYL
                     CDRRLNSDIDIGIIGTHHHRELEFSRGENIDFWNEYTNMRKGKDKEKFLLQGNYYDYY
                     KEHKAQNSILNYEVLKEVELTIFISCKDDEELEFIRKKLESPCKYANLGRKEDFVIPS
                     EKGCFVKEVALKEVIPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPH
                     KYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCIDTKEVFTWL"
     gene            17694..20102
                     /locus_tag="PC465_001847"
     CDS             17694..20102
                     /locus_tag="PC465_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HDF2649145.1"
                     /translation="MKNIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNL
                     YSDKDVEILKICCALHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIA
                     RHNIFSGAFLKNILEKMNLSEEDKLYIYKSIMLHHGNYEDYMRLSTSKVQKEIYDYIE
                     KGILEKEDFNLEDIEDYIKEILYVDFKFNEDILDYDYIDKLSESMVIYSDYNNGQIED
                     SVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDNMILNEIYKSQGNLE
                     KNNIEFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISAESFYR
                     KNIFQNKNDLDTRSSNDYIGLLHGDINLYSENEDNGEHDFVLTLRDIDLSINFCKPCV
                     IATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDV
                     DFHLMTATLPKSYKEQMINKGIIFQEESNENVTDKGEIVFIESNKEEEICEGKDVKVS
                     FIKEKEIKSIVEDALENKQKILIIKNTIDSVNRTYEFLKENLSDKYGGVDIDVLHSRF
                     KFKDKKEKYSKILNGEGDIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNN
                     KYEYGNFYILPSEDKIYDNKLKSTTKNILKDILKTNSIFTMGIRKTILDDYYDNSVVK
                     KYFEENFISCDKEIKNIYGVNKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDVDVSY
                     KIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYGLISKVEGYMVLKSSSKFEYNSTVG
                     LILK"
     gene            20544..21491
                     /gene="prmA"
                     /locus_tag="PC465_001848"
     CDS             20544..21491
                     /gene="prmA"
                     /locus_tag="PC465_001848"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HDF2649146.1"
                     /translation="MNNWIEVTIKTTTEAVEPITNILYEQGAGGAVIEDPKDFLFQKK
                     NELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKQKVLGLKDFGIDIGEGS
                     VSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQEGDLIIELDPGMAFGTGT
                     HETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKE
                     NVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISS
                     GIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKK"
     gene            21510..22268
                     /locus_tag="PC465_001849"
     CDS             21510..22268
                     /locus_tag="PC465_001849"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HDF2649147.1"
                     /translation="MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRCKLGEKLEICD
                     KNNNEYICEIMNIDKSIVNLEILEKVDINRESELKVRLYQGLPKAPKMEMILQKLTEV
                     GVEEIILVQTKRSVVKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLSFKEAL
                     EDMKKNNVNICPYENERTVSIKHALKKCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNC
                     NVVSLGPRILRTETASVVASTIALYELSDLGGEK"
     gene            22270..23568
                     /gene="mtaB"
                     /locus_tag="PC465_001850"
     CDS             22270..23568
                     /gene="mtaB"
                     /locus_tag="PC465_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HDF2649148.1"
                     /translation="MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVI
                     NTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDR
                     RKIVEEIKKINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCI
                     IPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQ
                     INQIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYT
                     TLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLKEIELSQMHIFKYSP
                     RKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRELDVLFEQNIEGNKY
                     EGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL"
     gene            23611..23961
                     /locus_tag="PC465_001851"
     CDS             23611..23961
                     /locus_tag="PC465_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HDF2649149.1"
                     /translation="MDCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKK
                     HYDSLIDIPDKEMDIVSHIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHI
                     LAGKKLPNYEAGQN"
     gene            24124..24303
                     /locus_tag="PC465_001852"
     CDS             24124..24303
                     /locus_tag="PC465_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HDF2649150.1"
                     /translation="MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVK
                     RKKKAEAARRKNAKK"
     gene            24333..24776
                     /locus_tag="PC465_001853"
     CDS             24333..24776
                     /locus_tag="PC465_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HDF2649151.1"
                     /translation="MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVEL
                     DEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEI
                     VKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ"
     gene            24887..25384
                     /locus_tag="PC465_001854"
     CDS             24887..25384
                     /locus_tag="PC465_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HDF2649152.1"
                     /translation="MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQL
                     TKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWS
                     ILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLIYLMWLVYAGFLNYFI
                     WFINK"
     gene            25577..26140
                     /gene="raiA"
                     /locus_tag="PC465_001855"
     CDS             25577..26140
                     /gene="raiA"
                     /locus_tag="PC465_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDF2649153.1"
                     /translation="MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAK
                     KDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKS
                     IRFENLDFIDNSSEFDDYDYDDEEDENIVIERRKKFNVKPMSSEEAILQMELVGHNFY
                     MFRNQDNFEINIVYKRKAGGYGLIEQD"
     gene            26353..26589
                     /locus_tag="PC465_001856"
     CDS             26353..26589
                     /locus_tag="PC465_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HDF2649154.1"
                     /translation="MLEISTDLQVNQPVITVTSNTFISIENYLSILEYEVDLIRIKTK
                     VKTIKISGDKLSLKYITDSEIGIKGIIYNVEYVD"
     gene            26602..27945
                     /gene="yqfD"
                     /locus_tag="PC465_001857"
     CDS             26602..27945
                     /gene="yqfD"
                     /locus_tag="PC465_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YqfD"
                     /protein_id="HDF2649155.1"
                     /translation="MISFIRGYYVIVVEGVRLEQFLNHLIRNGISVYNVTRIKNTKME
                     FHIDRQDIKEFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTS
                     QFVTDVYIQSPEGIKKEALRNELYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSI
                     NVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKG
                     DVLLNGANTKSIPEVWASTFYESTKKASYVDTVNKKTGEKKNIYTLSFYDKEFTMRKN
                     IKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKRNKEELKKELSEKALKEL
                     EYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPD
                     EGEEEVPSNPEKRPLNDIRNEFDEDNKDNKDQNNSDENNSNQNSNNSQNNNSNNN"
     gene            27884..28999
                     /locus_tag="PC465_001858"
     CDS             27884..28999
                     /locus_tag="PC465_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HDF2649156.1"
                     /translation="MKIIVIKIVIIVKIIIAITTNKIKLKILGGLIQLIIQKKFTIAD
                     GNFERELFGNFDENVKLIEKTLNIDVILREGNIILIGEEKNVDSALKLMNELHQTVSN
                     GKHLDKQSISYSLSLLLEGSEQKIKELEGTIVITQRGKAVQPKTLGQKEYIKLIENND
                     ITFGVGPAGTGKTYLAVAMAVKAFKRDEVSRIILTRPAVEAGESLGFLPGDLKDKVDP
                     YLRPLYDALFEMLGADKFNKYLERGTIEVAPLAFMRGRTLDNSFIILDEAQNTTSEQM
                     KMFLTRLGFGSKAVVTGDVTQTDLPQNKKSGLIQATEILKGVPGIGSIMLTDRDVVRH
                     ELVQRIIRAYEKHDKREEFKKEERKKAKMQEKTFKRK"
     gene            29056..29517
                     /gene="ybeY"
                     /locus_tag="PC465_001859"
     CDS             29056..29517
                     /gene="ybeY"
                     /locus_tag="PC465_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HDF2649157.1"
                     /translation="MDLILDDRQDKLEVSEELIEKIKDIIIECLDYEGYDDNYEVSLS
                     FVDNKEIHELNREYRGVDRVTDVLSFPLLSDDFEDVELEEESLGDIVVSLERALEQSI
                     EYNHSFEREVCFLICHSMFHLLGYDHDTDENTKEMREKEEHILNKLNITRE"
     gene            29523..30242
                     /locus_tag="PC465_001860"
     CDS             29523..30242
                     /locus_tag="PC465_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDF2649158.1"
                     /translation="MKPEKTRQGIIKAFNAAIEGILYTFKFERNMKIHYLGSVAVLII
                     SLFFNFSKLEMIMLLMSICLVVVAEMFNTAIEKAVDLVTDEYHVLAKIAKDVAAGGVL
                     VAALNSVVVGYILFYDKLTDISGILIYKIRESELHITLICILLVLIAVVVVKALTSTG
                     TPLKGGMPSGHAALAFAIATAITLMTERVVASTLAYIMAVLVAQSRIEGKIHTFWETI
                     AGALLGVLIAILVFQLGMFYN"
     gene            30361..30762
                     /locus_tag="PC465_001861"
     CDS             30361..30762
                     /locus_tag="PC465_001861"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDF2649159.1"
                     /translation="MDNIELLRLAEDARQHSYAPYSGFRVGAALLTKSGKVYTGCNIE
                     CASLGGTNCAERTAIFKAISEGDKDIYKIAIASDNSENNEQTYPCGICRQVIIEFGSD
                     IKIITGYTKGEVFEHSIKDLLPNYFSGNDLK"
     gene            30862..31755
                     /gene="era"
                     /locus_tag="PC465_001862"
     CDS             30862..31755
                     /gene="era"
                     /locus_tag="PC465_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HDF2649160.1"
                     /translation="MFKSGFVSIVGRPNVGKSTLMNNVVGEKIAIMSDKPQTTRNTIQ
                     AVYTDEEMQIVFLDTPGIHKPKNKLGEFMVKAATEAFKNVDLILFVVDDSKKIGPGDR
                     KIIEDLRSVKTPIILVVNKIDQLDQKDELFDIIKMYDREGIFKEIVPISALKGKNTDT
                     LIKVIQNYLEEGPKYFPDYMITDQPERVLIAELIREKVLHYLNDEIPHGVAVEIEKMK
                     ARNDKEIVDVSAVIYCERDSHKGIIIGKNGRKLKGIGKSARQDIELLLGSQINLQLWV
                     KVKENWRNLQNYINNFGYNDK"
     gene            31767..33146
                     /gene="mgtE"
                     /locus_tag="PC465_001863"
     CDS             31767..33146
                     /gene="mgtE"
                     /locus_tag="PC465_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HDF2649161.1"
                     /translation="MDRKLDASQDLLYEVKSLIDNNKVLELRELIEEYHIIDIFDIME
                     NLEEDMKIQLFEVLPLDMASSILEEGSVEFFISILSKLDVEHSKNILELMSLGDMADK
                     LSELEEEEREHIINLLNQENADYVKELLFYDEDSAGGTMTTGYISINKDMTALEAIDH
                     MREEAEEAETIYYIYVVDDEEKLVGVLSLRELIIARDANIVEDLMSENIISVYVDEDR
                     EEAVRLVSKYNLIAIPVVDRQEKLKGIITVDDIIDVMEEEATEDMYKFAGSSEHEREV
                     AEKENPTLREQIISALRGRLPWLIITLVGGLLASLILSNLDYIMNPVYAPLVFFIPVV
                     IGMGGNIGTQSSSVTVITLSNKDLNFSNVVREGIVGIITGLLCSIITGIVIYFVMRKL
                     DIVLIVSISLFINMVLGATIGAFMPVLLKKMDADPSTVSSPIISTALDITGIAVYFII
                     TTALLSKIV"
     gene            33219..33374
                     /locus_tag="PC465_001864"
     CDS             33219..33374
                     /locus_tag="PC465_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqzL family protein"
                     /protein_id="HDF2649162.1"
                     /translation="MNNISWEVFKKTGSIDAYLYFCDCKNIHEEIEEVREKKEDDDNP
                     EHPGDST"
     gene            33340..34113
                     /gene="recO"
                     /locus_tag="PC465_001865"
     CDS             33340..34113
                     /gene="recO"
                     /locus_tag="PC465_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HDF2649163.1"
                     /translation="MIILNTQGIVLKAIRYKESDIILTLFTRKLGKVSAIAKGAKKNK
                     SSLLSSSQLFSYSNFTLKKQGNMYKVTQSEIIKSFYNISYDIEAFSYATYITKLVENS
                     ILENQTNNRLFILLAQTLYLYTQDNTDNRFITAAFELKFLDYIGFKPIVNKCINCECK
                     ILQNSVFNIYEGGILCSKCSKLFDNNIKLDLTTISLMEYVLRNDILTCSKAKVSKYIT
                     HELENILDKYLKVYVDNINFKSLHVLQSVKNNKGVDNDE"
     gene            34106..34705
                     /locus_tag="PC465_001866"
     CDS             34106..34705
                     /locus_tag="PC465_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4342 domain-containing protein"
                     /protein_id="HDF2649164.1"
                     /translation="MSSNITIEMVDSVFERVPGATYAEAKEALVMCNGDVIEAVIYLE
                     NKKNTCNCKAKSAKETMEEVFGKDGENIKFQLKELLRKSSVVRIIVEKDGKTMMNIPL
                     TVGVVGLAFVPLATLVGLSAAVISKYRIKVQNEEDGEIVDLGELNEEKLHVLKNMITN
                     AAKDVKDVVVDKKEDDKDVTADLMKEESEKNKEDEDENK"
     gene            34865..35743
                     /gene="glyQ"
                     /locus_tag="PC465_001867"
     CDS             34865..35743
                     /gene="glyQ"
                     /locus_tag="PC465_001867"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HDF2649165.1"
                     /translation="MNFQEMILALQKYWSKQGCIMMQPYDIEKGAGTMNPNTFLRSLG
                     PEPWQVCYVEPSRRPADGRYGENPNRLYQHHQFQVILKPSPDNIQELYLESLKEIGID
                     PSEHDIRFVEDNWEAATVGAWGLGWEVWLDGMEITQFTYFQQVGNIECELETGEITYG
                     LERLAMYIQEVDSVYDLKWNDKITYGEVFNKAEYENSMYAFELCDADMLFNLFDIYEK
                     EALRLMENGLVIPSYDYVLKCSHAFNTLDARGAIGVSQRASFIGRVRNMAKTVAETFV
                     KQREEMGFPLLKDGDK"
     gene            35743..37809
                     /locus_tag="PC465_001868"
     CDS             35743..37809
                     /locus_tag="PC465_001868"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HDF2649166.1"
                     /translation="MKNYLLFEIGVEEMPSRFVGSTLEQLKNNLSKLFDENRIAFDKI
                     NAYGTPRRLTLVVEGLSDRQNDLEEEIKGPAKKIAVDAENNLTKPALGFIKSKGLSES
                     DIYFKQVGKEEYIFATIKQDGKETSEVLKDILPETIKSVVFPKAMRWGGKNLKFARPI
                     RWIVTLLNDKVLEFDLEGIISSNVTKGHRFLGESTIEVDSIEDYFEKLEKNYIVLDQN
                     KRKEMIRKQCIEVANSLGGEVEFDEDLLEEVTYLVEYPTAFYGEFDVDYIKLPKEVVI
                     TPMKQHQRYFPVLKEGKLLPNFIAVRNGDSYRIDNVKAGNEKVLEARLADALFFYRED
                     TKRNLESYIEKLKTVVFQVKLGTIYDKTLRLEKLSADILDSLGLVDEKADTIRAAKLS
                     KADLVTGMVGEFDELQGFMGKEYAKVGGENDVVSEAIFEHYLPRFAGDILPKTNAGVA
                     LSIADKLDSIAGFFAIGIQPTGSQDPYALRRQALGILSILMDRKVAVDIKVLIEHALD
                     NYSELDFNKEEVVEQIMSFFNERVKNLFKDLGIRYDVVDAVLSSDINDVSDMHMRALE
                     LNNWLEKDELVEMLTAFNRVSTLAQKAESDKIDESLLKEDAEIKLYNEFKQVKVKVNE
                     LLKDKKYGIALDEFASLRPVVDNLFDTVMVMDNDEAIKNNRLALLKQVYDTMLEICDL
                     SKIVYK"
     gene            complement(37975..39522)
                     /locus_tag="PC465_001869"
     CDS             complement(37975..39522)
                     /locus_tag="PC465_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HDF2649167.1"
                     /translation="MDNFKKILLNELPNFKEYSSKFLNGEINKMQYKGFSGGYGVYAQ
                     RDKKSFMIRLRVSAGVLSQYQLNKIYEIAIKHNLDKIHLTTRQAIQLHDLSINSIVDI
                     MEEGIKNDIFTRGGGGNYPRNVGLSPLSGVDPSEVFDVTPYAVATDKYFIKNATTYHL
                     PRKLKVSYSNCYTDTAHCSIQDLGFVATLKNDEPYFRVFLGGGLGKQPKVALELDELI
                     KPKDALYCVEGMIKFFMDYGNYENKNRARVRYMVESLGEELFLEKFKEYYKLEKENGS
                     LELNIEEIDYSKPGVKIDIQDSRLIPQKQDGLYTVYIHPVGGILLTKDLSTLLKELDN
                     VENPMIRLGMTEGLYILNLNGNEAKRILEISKTISCNSQLEQSISCIGVPICQMGIQN
                     SQKMLHEIIDYFRLQNNEEILNKAPKLYISGCLNSCGVHQVGSIGLCGKKKNVDGIST
                     DAFELFVGGSFEIGKTRLGKSLGDFKASDIPEMLYKISDASSGNFYEWVNSNDNILNK
                     ITDKYKI"
     gene            39802..40569
                     /locus_tag="PC465_001870"
     CDS             39802..40569
                     /locus_tag="PC465_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HDF2649168.1"
                     /translation="MGEIINALDRALDIILLLYHEKREMGITEISKAMGVYKSTVHRT
                     LVTLENKGFVIQNAENGKYWLGINLYAIGMVVGEKMSLTEIVKPYTKKLNQEFNEVVN
                     VSILEERAQDSPRSIIIHKEYGSNQLLSVNPSVGSSSECYCSAVGKCLMAFNDSIDFE
                     KYRKTPIHKYTEHTIDNWDDMMLFLAKIKEQGYAIDDEELEHGLTCIGAPILDKNNKA
                     IAAISLSGPTIRMREGDFEYKIKRVIETAKSISELFR"
     gene            40852..41049
                     /locus_tag="PC465_001871"
     CDS             40852..41049
                     /locus_tag="PC465_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2649169.1"
                     /translation="MEKVKLSVERCKGCYLCIEACKKDAISLSDYKNKKGFVTIKVDE
                     EKCIQCGACYTMCPDLVFEIL"
     gene            41078..42154
                     /gene="vorB"
                     /locus_tag="PC465_001872"
     CDS             41078..42154
                     /gene="vorB"
                     /locus_tag="PC465_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HDF2649170.1"
                     /translation="MQSLLIKGNEALAEGAIRGGCRFYAGYPITPQSEILEMMAWRQK
                     EVGGVFIQGESEIASVNMVMGASALGARAMTSSSGPGFSLKQEGIAYWVSAGLPAVVA
                     CVQRYGIGDGFIGAGQDNYWQAVKGGGNGDYHLIVLAPNSVQENMDMAYESFELAEKY
                     MHPVLILSDATIGQMVEPCIAPPMKEYDMDKAPWAAKGTPVGEKNKVITDITYFEDQD
                     TWQKGYIEKMRKVQEDEQRWEEIEIEDAEVVFVAYGISSRIAEGAVRDARAKGMKLGL
                     IRPKTLWPYPRKAFKKLSDSLKGLVTVEMNMMAQMKEDVIIACDNRFPVYSVATAQYM
                     AEVNQLIDFAQQIIDGKAKQEEVF"
     gene            42157..42876
                     /locus_tag="PC465_001873"
     CDS             42157..42876
                     /locus_tag="PC465_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HDF2649171.1"
                     /translation="MAKKAPAIMMCENMFCGGCGHSIVDRIIGEVLTEMDICQDTIIC
                     SDIGCNHMFQFSMNVDVVVPPHGKMGAAMAAMKRVRPDKYIFTIAGDGGAYAIGLGET
                     MSAATRNDNVIFLVMNNNMFAMTGGQMAPTTIEGQYTASTPAGRNYADHGSTFDVVKV
                     MGNLDIAYLARGTITNPKEINTTKRYIKKALEKQKEKKGFCLIEVLVPCPTNWGLKPV
                     DAMKRIENELVPKYPLGEFID"
     gene            42889..43428
                     /locus_tag="PC465_001874"
     CDS             42889..43428
                     /locus_tag="PC465_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HDF2649172.1"
                     /translation="MLNEIICAGFGGQGVLTAGKIIMYVAYKAEKKITWFPSYGNEMR
                     GGSANCNVVVSDEKIANPCVKNPDILLGMNSVSVDKYESLMKKNGYMFVNESLVSKDR
                     KYREDINVIKVPVTEIAQNLGNEKAANICMLGAMVKSLDLFTKEEFESGMCEYFENQG
                     KGKFNSKNVEAFEAGYDYE"
     gene            43585..44643
                     /gene="buk"
                     /locus_tag="PC465_001875"
     CDS             43585..44643
                     /gene="buk"
                     /locus_tag="PC465_001875"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HDF2649173.1"
                     /translation="MKVLVINPGGTSTKISVFQDENEILKKNITHTREDLKNFSKVFD
                     EYDYRKQLIVDILSSENHSINSFDAVVGRGGLMKAIKGGTYTVSEEMIEDMRNEINGE
                     HASNLGALLAKTIADEIGVQSFVVDPVSVDEFDDVSRITGISDIEKASWLHALNHKAV
                     SRKIAQKLGGKYEDYNFIVAHLGSGISIVAHKQGKMIDGSGGRSDGPFSPERSGGLLA
                     YPLIELCYSGKYTHDEMVAKVSSIGGMYDYLGTKDMIEIENRIKEGDEKAKLIMDAFI
                     YQVAKEISMYGASLSGNVDRVILTGGISHSEMVVKGVAEKVSYLAPIEIVPGEMEMEA
                     LALGALRVLNGEEIAKTY"
     gene            44661..45554
                     /locus_tag="PC465_001876"
     CDS             44661..45554
                     /locus_tag="PC465_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HDF2649174.1"
                     /translation="MLKDFNNLLEEAKKLEPVIVSVAVAEDKEVLKAVKSATDLNIIK
                     PILVGDKDKIESISREIGLKGHEIIGCQNPDESVKKAVEIVKNKEAKVLMKGLVNTSV
                     YMRAILNKETGLRTGRLLSLLAVYELPQYHKLLYCTDSGINVSPNLNQKKDIMTNVLL
                     TMKSIGMENPKTAILTANEMVDPKIQSTVDANLLVEMEKSGEIPKCIVEGPIAFDVAF
                     DAHAAEHKGIKSNIAGDVDLLVFPNIEAGNILGKSWLRFNKAKWAGIVLGATNPIILG
                     SRSDTAEIKINSIALACLASQ"
     gene            45584..46792
                     /locus_tag="PC465_001877"
     CDS             45584..46792
                     /locus_tag="PC465_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2649175.1"
                     /translation="MKYAKRMDMVKASAIRDSQKKIAQKVASGGTVISFAAGLPDPNL
                     FPIEEISEITQKVLNERGKFALAYGPTKGEDELLDLLVKRMKEEENIDTKAENIIITT
                     GSQQGIALSAMILLEKGDVVVTENPSYLGAINAFRPYECDFLGVDTDEEGMVTDDLDK
                     LLSENSNIKVIYVIPTFQNPTGKTWSLQRRKDFMEVVNKYDVIVIEDNPYGEIRFTPE
                     PLPTLKSLDTKDKVLYLGSFSKVLCPGFRVAWMCGNVDIIDKAELLKQGIDLQSNQFS
                     QVQVIEFLKKYNLNEHIEKIRAEYKKRCLLMLDAMKKHFPEEAKYTEPDGGMFIWVEL
                     PESINVDDLLDKAIDAGVAYVSGESFFANNGPKNTMRLNYTTMSEEQIVKGVEILAEV
                     IKKELNYACE"
     gene            46816..48075
                     /locus_tag="PC465_001878"
     CDS             46816..48075
                     /locus_tag="PC465_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2649176.1"
                     /translation="MGEKENGIKFGKLMFQLVIIAISWELVYIIPFIQYTLYDPILKA
                     LECTNTQLGFLLTIYGLGNIFGAPIGGWLADRFDYRKIILGSVFLNGVVSFLFAFNMN
                     YPFAVATWVGCAITSLVMNYPSMVKILRVIGKDNQGKVYGFNEAMVGVSGVVMGAIFL
                     YIYTCFATPTLGMRWVMISLGILSIAMCPVLWFVIKDVDIKEEREEAGEKMSAGDFIT
                     VLKSPNTWLVGISIFCVYSFTVTMSYFTPYITSVLGGSVALSGTLAIIRQHGLKLFGA
                     PFGGYCADKLKSPTKVLLPIYVFGIAVIVLFLVLPASTPMTIFIALTFVVGILGYMGK
                     GIYYAVQDEVKVPVKYSATTIGIAAALGFSPDVFQFALIGHWIDTYGNKGYTYTFIFQ
                     IAILVIGILSCLYILKVKKRRASKLEA"
BASE COUNT        19325 a         5066 c         8798 g        15241 t
ORIGIN      
        1 taaaaaacat agaataaaat acttatttag ataaaataaa taatttttag agaatatttt
       61 agaagttacg attgtatgat ttttaaatgc ataggcattt actctaggac tatagactaa
      121 tataaaaaaa aactttggga atactaaaac cataaattta taaaattaat attttatata
      181 ctgtaaaaca gtgaggaggg acagtatgca tactcaacta caaaagacta ttggtctttc
      241 agcagctctt tctactgttg taggtatggt tataggttcg ggagtttttt ttaagccaca
      301 agcaatatac actacaacta atggagctcc aggtctaggt attatagcgt ggcttttagg
      361 tggttttata acaataactg ctgggcttac agctacagaa atttcagctg ctataccaaa
      421 aactggtggt atgatgattt atatcgaaga aatatatgga gaaaagttag gttttttaac
      481 tggatggatg caaactgtat tatttttccc aggtacatca gcggcattag gagtaatatt
      541 tgctcaacaa gcatctgaac ttttaggaat gagcccaaat aatatggcaa atgtacttcc
      601 tatagcaatt ggagttatac tatttttagc gttattaaat ataataggtt catccttagg
      661 aggaaaagtt cagacagtag ccactattgg aaagatgata cctttaattt taataatagt
      721 ctttggattt attaaaggtc aaagtagtga agtattaaat ccatttgtag gagatggtgt
      781 aaatgcatca aatgcacttg gacaagtatt aatagctact ttgtttgcat atgatggttg
      841 gataaatgtt ggagctatat caggagaaat gaagtctcca gagaaagatt taccaagagc
      901 aatagttggt ggtttatcat tagttatggc agtttatatt ataataaata tagcttatct
      961 ttgggtagta ccagcaagtg aattagcaac agttacttcc ccagctacat tagtagcaac
     1021 aagattgttt ggaaatatag gtggaaaagt aataactgtg ggtatattaa tatcagtatt
     1081 tgggacattg aatggatatt tattaacagg ttcaaggata ccttatacat tagctgaaat
     1141 gggaacttta ccagcatcta aaactctttt aaaagtaaat tctggaggtt ctcctgtaaa
     1201 ttcaatacta cttataactg tgttagcctg tgtatatgca ttatctggtc aatttaatct
     1261 tttgacagac ttaacaatat tttcaatatg ggtattttat gtattgactt ttataggtgt
     1321 tatgaggctt agaagacaaa agccagattt acacagacca tataaagtcc ctttatatcc
     1381 aataatacca attatagcta tattaggtgg actgtttgta ataataaatc aaatattgac
     1441 ttcaacagtc atatctttag gcggaatatt tataacacta ttaggtttac cagtttatta
     1501 ttatatgaaa aaaagataac tacttaattt aagttagata aatttgggta aaggtgaaaa
     1561 ttaactttta tccaaatttt ttatactgtt atacaatata agtattatat attgcttgat
     1621 gtgctatttt gtttgattta taatttagta attgatgttt taagataatt taagaaatga
     1681 ggagtgaaag atgctaggac tttatgtaca tattccattt tgtgtgaaaa aatgtaagta
     1741 ttgtgatttt aattcttata aaatggacat agattcaaaa aaaagatata tagaagactt
     1801 aaaaatagaa atggaattat atagtaataa attatataaa gataataaat ataaaaataa
     1861 agaatgctgt agtctaaata aaaatgacaa aataacgagt atatttgtag ggggaggtac
     1921 acctagtata ctaacctctg atgaaataag agaagtattt ataagtataa aagaaatgtt
     1981 tgatatagat gagaatgcag aaataactat agagtgtaat cctgggacat taacattaga
     2041 aaaattaaaa actatgaaag agattggcat aaatagactt agtatagggc tacaagctat
     2101 tcaagaaaag catttgaact ttataggaag aatacatact tatgaagaat ttgagaaaaa
     2161 ctataaagat gcattaagtg taggttttaa aaatattaat gtagatttaa tgtacagtct
     2221 tccaaatcaa actctatgtg attggaagga aactcttgaa aaagttgtac acttaaatcc
     2281 aacacatata tcagcttatt cccttatact agaagaagga actgaactat acaatatgta
     2341 tgaaagtaat aaatttgaac ttatagatga aaatgtagat atagaaatgt atgagtatac
     2401 aataaactac ttaaagtcaa aaggatataa tcaatatgaa atatcaaact actcaaaaga
     2461 aggctataat tgtgagcata atattttata ttgggaatgt gaacattata tagggattgg
     2521 agcaggagct tctggctata ttaatgagaa cagatacaat aatgtagaat ctttagaaga
     2581 ctatcattta agtttggtaa aaagagaaaa accaatacaa gaaaatgaaa ttctttctga
     2641 gaaagatatg atagaagaaa agatatttat ggggcttaga atgaataaag gcataaaatt
     2701 tgaagatttt aaaaaaaaat ttggaataga ttttagagag aagtataata agcaaataga
     2761 aatgctatta gctagaaagc ttataaatca gagctttgaa ggtatacaat taactcaaaa
     2821 aggaagagaa atatctaata gtgtatttat agaatttatg gaataatttt taaggtgttg
     2881 acaaaataaa tttataatgg tatataatat atataatctt tttagcactc gaacttagtg
     2941 agtgctaaca gctaggaggt ataataatat ggaattaaat gaaagaaaat taaatatcct
     3001 caaagctata gttaaagatt atatagaaac agctgaagct ataggttcta gaacaatatc
     3061 taaaagacat gatttaggtg ttagtgctgc taccataaga aatgaaatgg ctgaccttga
     3121 agaattaggg tatttaattc agcctcatac ttctgcgggt agagttccat ctgaaaaagg
     3181 ctataagtta tatgtaaact ctcttatgag taaaagcgaa ttggatgata atgataagat
     3241 tcttattgaa caatgtatga atcacaatat aaatcatata aaagaattga ttcatgaaac
     3301 ttctaagcta ttatcgcaac taacaaacta tacaactgta gcagttacta agagtttaat
     3361 aaatcaaagt gttataaagc acatacagtt ggttgctatg aatgacaata atattttact
     3421 tatagttgta acagataaag gggacttaaa aaaagctaac cttacaacta atgtatattt
     3481 agatcaatct aagttaaatt tgatttctga taatcttaca aggaagctct taggtaaaag
     3541 tataacagat ttggatgata atctaattgc ttttattaaa tacgaaataa gtgagtattc
     3601 tgggcttata gatgagcttt taaatgcttt gaactcaaat atgaaagaag aagatttttc
     3661 tctatcatta aatggagcta ctaacatatt tagttatcca gaatttaatg atgtattaaa
     3721 agcaaagtca tttttaaata tgttggaaaa aaaggaaaca atagctgaca taattaaatc
     3781 aaagggaata caaaaagaca atctaaatat aataattggt agtgataatg attgtgaact
     3841 ggcacaggat tgtagtatag ttacagcaac ttataatgta gatagagact tggttgggcg
     3901 aataagcttt ataggcccta ccagaatgga ttatgctaga atttactcta taataaatta
     3961 tatgagttta ttaattaata gaaagtaaag aaattttaaa ttgcgaggtg taaagtcttg
     4021 gataaaaaaa atgagcaaca ggaagtaaga gaagaaaatg atacttctat taaccaagaa
     4081 tcggaaactc aagtagagtt agaagaggaa gttgttaatg aagaatgtga aacatcaagt
     4141 gaaaaaactg atgaaaaaga agttgatgat gaaaatgtaa cagatataaa ttctaagtta
     4201 gcagaaaaaa aattgcagga tgagttggat gaattaaatg ataaatatca aagacttcaa
     4261 gccgaatatg caaactacag aagaagaact caacaagaga aagagacaat aggcgtattt
     4321 gcaaatgaaa aaataataac tgaattgata ccagttatag atagtatgga aagagcctta
     4381 gatgcatgtg aagataagga agatactatg tataagggta taagccttgt acataaacaa
     4441 ttaatagaca ctttagtaaa atttggagta gaagaaatag aagcagaatc taaggaattt
     4501 gaccctaatc tacatctagc agttatgcaa gaaagtgtag atggagttga agcaaatcaa
     4561 atagtaatgg tacttcaaaa aggatataag ctaggaacta aagttgtaag accttcaatg
     4621 gttaaagttt cttgctaagt ataaattaaa ggttaaatta tttaacctaa tataaaatat
     4681 taaaataagt aaaacttaat tatataatta ctcgaggagg attttagtca tgggaaaaat
     4741 aataggaata gatttaggaa caacaaattc atgtgttgca gtgttagaag gtggagaagc
     4801 acaaataata gcaaatagtg aaggtatgag aactactcca tcagtagtag catttacaaa
     4861 agatggtgaa agaatagttg gagaacctgc aaaaagacaa gcagttacaa atgcagataa
     4921 aacaataact tctataaaaa ctcatatggg aactgattat aaagtaaata tagatggaaa
     4981 atcatatact ccacaagaaa tatcagcaat aatattacaa aaattaaaat cagatgcaga
     5041 aagttactta ggacaaacag taacagaagc agttataaca gtaccagctt actttacaga
     5101 tgctcaaaga caagcaacta aagatgctgg tagaatagca gggcttgatg ttaagagaat
     5161 aataaatgag ccaacagcag cagctcttgc ttatggtatg gataaattag accaagaaaa
     5221 gaaaatatta gtatttgact taggtggagg aacttttgac gtatctatac ttgaaatagg
     5281 agatggaact tttgaagttt tagctacagc tggtaacaat agattaggtg gagatgactt
     5341 tgaccaaata gtaatagatt atttagcaga ggaatttaaa aaagctgaag gtgtagattt
     5401 aagaaatgat aaaatggctc ttcaaagatt aaaagaagca gcagaaaagg ctaagaaaga
     5461 attatcatca acaatgagtt caaacataaa cttacctttc ataactgcta cagcagaagg
     5521 accaaaacac ttaaatatag atttatcaag agctaaattt gaagaattaa ctagaggttt
     5581 agttgaaaaa actatggaac caactaagac agctttacaa gatgcaggac tttctacagg
     5641 tgatatagat gatgtattat tagtaggtgg ttctacaaga ataccagcag tacaagaagc
     5701 tgttaagaag tttataggaa aagaacctca taaaggtata aacccagatg agtgtgttgc
     5761 agcaggtgct tctatacaag ctggagtttt agcaggggat gttaaagact tattattact
     5821 agatgttact ccattatctc ttggtataga aactatgggt aatgtaatga ctaagataat
     5881 agaaagaaat actacaatac caactaagaa gtctcaaata ttctcaactg ctgctgataa
     5941 ccaaacagct gttgatatac atgttcttca aggtgaaaga agtatggctt atgacaatac
     6001 aactttagga agattccaat taacagatat accaccagca caaagaggaa tacctcaaat
     6061 agaagttact tttgatatag atgcaaatgg tatagttaat gtttcagcta aagatttagg
     6121 tacaggaaaa gagcaaaaaa taactataac atcaaacact aatttatcag aagcagaaat
     6181 agagcaaaag ataaaagaag cagaaatgaa tgcagaagct gacaaacaaa agaaagaaaa
     6241 aatagaagca ttcaatcaag ctgaatctac tatatatcaa actgaaaaaa ctttaaatga
     6301 acttggagat aaaataagtt caggtgaaaa agaggatata gaaaaagcta tagcagattt
     6361 aaaagctgta aaagataatc aagatgctac agcagaagaa cttaagaaag ctacagatga
     6421 agtaatgact aagttccaaa aagtatctca agaaatgtac caaaaagcag ctcaagaaca
     6481 acaagcggca caaggtgcag aacaagcaca agacaatgga cctaaagatg acaatgtagt
     6541 agatgctgac tttaaagaag tagatgaaga taaataagct atataatatg taacactaaa
     6601 tgataattgg aacatatatg atttgtgaaa atcatataga tgttaaagat atatggacaa
     6661 tatacatcat aaagaatata atatatcata gattatataa cttaaagtag aatataagaa
     6721 ttaatgatag cttgtagttt attattctac aagctatcgt tttgtaaaat gaaggtggtg
     6781 tcaatttttg agtacaaaaa gggattatta tgaagtctta ggtatcagta aaggtgcaga
     6841 agctcaagag ataaaaaaag cttatagaaa attagcaatg aagtaccatc cagatagaaa
     6901 tcctggagat aaagaggcgg aagaaaaatt taaagagata aatgaagctt atgaagttct
     6961 atctgatgat acaaagagaa aaacttatga ccagtttgga catgatgggc taaatggtca
     7021 aggcggtttt ggtggtcaag gaggatttgg cggtcaaggc tttggtggtt ttgaagatat
     7081 gttcggagat atatttggtg acatgtttgg aggaagcttc ggaggtggaa gagcaagaag
     7141 aagaggacct caacgtggtg cagatataag acagagtgtt actatatctt ttgaagaagc
     7201 tgcatttggt aaaaagatgt ctataaaagt aaatagaagt gaagagtgtg aagaatgtaa
     7261 tggaactgga gcaaaaccag gaacatcaaa gaaaacttgt tcaacttgta atggaactgg
     7321 tcaagttaga actgttcaaa gaactccatt tggtaatata gcaagttcaa gaccatgtag
     7381 tgcttgtaat ggaactggag aagtgattga atctccatgt agtaaatgtc atggaactgg
     7441 aaatacaaga aaagttaaga ctatagaagt agatatacct gctggtatag atgatggtca
     7501 aatgataaaa ctttctggtc aaggtgaagt aggagaaaaa ggtgctccaa gaggagacct
     7561 atatattgta gttaatgtta agtcacatcc actatttact agagatggaa atgatattta
     7621 ttttgaaatg ccaattacat ttgttcaagc aactttaggt gatgagatag aagtacctac
     7681 tttggatgga aaagttaaat atagtgtgcc agaggggaca caaactggaa ctgtatttag
     7741 acttaaagag aaaggaatcc ctagaattag aggtaattca agaggagacc aatatgttaa
     7801 ggttgtagtt gaaattccta aaaaattaaa cgataagcaa aaagaactat tgagagaatt
     7861 tgcgaaggag tgtgggtcga acgtccacga aaagaagaaa accttcggac aaaagataga
     7921 agatatgttt aagaaaaagt agttaaagta gccaatatat aatcatattt ttaaaatctt
     7981 agttatttat aagattgtca aaggagatat tatgattttt atattggcta tttttgtata
     8041 aaaaataaat gtgcataaaa taaaactgaa tataaataat tttctgaaaa atacttgtcc
     8101 taaaatatat aatgtgctat aatataatca aataaaagaa aggggtgatt ccagtgggaa
     8161 cggatgtggc actgccaaat gatgaagaaa actttattgt aatatacaaa ataaaattag
     8221 atacttttag tgctagatta agtactggaa aaactcatga gctgggataa ttattgtaat
     8281 tacctagact caaactttta gtagtaaaat agtaatatta tatagacaag gtatctaatt
     8341 tttaaatctt ttgtatgaat taaaattttt ataaagggta tatctgatta gaatgtaatt
     8401 agggaaacct agttgtgaat tacttttagt atatacatgt gtaaagaaat atgtatatgg
     8461 tattggttat tgtgctagat gtgtatgtaa agaaatatgt gtctagttgg gtatatgtaa
     8521 agaaatatac ttataatcta tgaaaaattt ttagtataaa ttgctaaaac attgagattg
     8581 ttttttatag aaagttagtt tataccaact aaaaatgtgc ttaagatttg tttgatgttt
     8641 aattataaat aaggttgtag ataaaaaaat aagtaaagac aaaggtttaa aatacttgct
     8701 ttaaatatag tttgttttga acacttgcca aattaaaata attaataaaa tagacatctt
     8761 ctcatagtaa aatatactgt gagaggatgt ttttgctttg ttcataaact tttatgaaaa
     8821 atttgcatag tgtcacattt taatatacta tatatataat aaaatataga taaaattaaa
     8881 tgattcaaaa gagaaaggtg aaaagagatg tattatatag gtgtagacat aggaggaaca
     8941 ggtatacaag caggagtagt tgataactat gggaaaataa tttttaggtc agagtgtaaa
     9001 acagtaattg aaaaaggatt tgaaggaata cttaatgaca taaaaataat gatttataag
     9061 ttgttggaag ataataaact tactatgagt gacataaaat ctattggatt tggtgttcca
     9121 ggttttataa ataaagaagg attagtaact tgtgtaaatt taaaatggaa taaaaaagct
     9181 tttaataaag agttaaaaag aagatttcca gatgttgaaa ttcatggaga aaatgatgca
     9241 acagtagcag cacttggaga agcaaagttt ggaagtatga aaggtgctaa tgttggagta
     9301 ttatatactt taggaactgg tgtaggtgga ggaatagtaa ttaatcaaaa agtcttttct
     9361 ggagcacatg gattgggttc agaaataggt catcaaatta taggagaaaa ctattttaat
     9421 tgtaattgtg gaaataatgg ttgtgtagaa actttttgtt cagcaactgc aattataaag
     9481 tattctcaaa aactgataga agaaggagaa aagagtagga ttttagattt ggcagaggga
     9541 aatttagaaa atgtaaatgc aaagatggtg tttgatgcat atagagaaaa tgatttagtg
     9601 gcaattaaag taataaatag atttaaagag tatttagcaa aaacttttgc aaacacaata
     9661 aattctttag acccagaaat tatatctata ggaggaggca tttctaaatc tagcgatata
     9721 atacttgatg gaatagaaga tttggtaaga aaatttgtat tatacaaaac agaagatata
     9781 gctacaatta catgtgcaac tttaggttca gacgcaggaa ttataggagc agctttttta
     9841 taatgtaaat gaactgctta ttggaggcgt gatgatatat gggtaaaaca aatgctagaa
     9901 gaacgctttt tttgatagca ataggttcag gaactatgct gaatcctctt aattcttcta
     9961 tgatttcact tgctttacat agtatacaaa atgattttca tattagtttt acaactgtat
    10021 cttggattgt ttcagcattt tacctagcta atgctattgc acaaccagtt tcaggtaaga
    10081 taggagattt aataggtaga aaggtcttat ttttgagtgg tttgatgctt gtaattttat
    10141 cagcatccat agtaccactt gttcaatcat tctttatatt gatttttata agagtaattc
    10201 aagcaattgg aacaagtacc ctatatccat ctggagttgc tcttatacaa aataatataa
    10261 aagaaagaca atcttctgca ttagcagttc taaccatttt tgcttcaact acagcaggat
    10321 taggtccgac acttggagga ttattgttgg acttaggagg atggcatgct atatttcttg
    10381 taaatatacc tgttgttttg gtttctatat gcctagggta ttttttattc ccaaaagaag
    10441 taaaagaaaa gaaatctata aaagaaactt taaaaaatgt tttgtcaaga ttagatatta
    10501 ttggcatact tctattttca attgcaatga tttttatatt actatttttg ctatctatga
    10561 aggaatcttt taacttagaa caacttgtat ttggtataat actgatgtgt ctttttattt
    10621 ggcatgaatt gagaacaaaa ttgccattta tagatattaa gctttttgta agtaatccta
    10681 aattgtcaaa agtttacttg caatttatta tattaaattt ctttaattat attttgtttt
    10741 ttggtcttcc tagttatttt caagatgcct tacattatag tgcaaagtcg actggattat
    10801 ttatgctatt tatgtctggt ataggtatat ttatatctcc attaactgga aaatggatag
    10861 ataaatctgg aactagattt cctcttgtta catcatcaat ctttatgttt attagtgcag
    10921 tacttctttc agtagttttt atccatatac ctgtaatagg aaagggtatt atattatcat
    10981 tagcaggtat tagttatgga gttggtaatg tagccctgca atcctctatg tttgaagaaa
    11041 gtcctcgtga cagtataggg acagcttctg gtctgtttca aactagtcgt tatttaggtt
    11101 ctattttagc aactgtttta cttggaatgg tatttgaagt aaatataaca tcagaacaat
    11161 ttcagatatt aggttatgtt atggtggtct taggtacaat aagtttttta ttaaatttta
    11221 tattaaagaa agaattaaga aaagtagaat agtggattta tggatttaat aagtctaata
    11281 actgataagt ttaaaaatat tgtttgtaaa acataactgg tttgatattt attaattcta
    11341 agttttgaag catagagtac tcgataagta tacaatattt tgaattaaaa ttaagcagaa
    11401 atttgaacta gtctttcaaa tctctgctta atttagtggt taaatttttt tatagagaaa
    11461 ataagatttg acacttagat aaaaaatcat tgcattttca aaattcttta aatcaaaccc
    11521 aagtatctca ttaatctttt ccaatctata tactagcgtg tttctatgta aaaacatact
    11581 agtagatgtc ttagaaatat ttaaatcatt atttataaat tttattcctg tatatagaag
    11641 ttcttcatca atagatttaa tcttattaaa atctattaat ttattgagta tattatcctc
    11701 attaattaaa tctaaagttt tatatctaat aaggtcaaac aaatttaaaa acttattttc
    11761 agcgttgtct tttataatat gaggtagtaa atcagaacat aactgtaatc taaaatcaaa
    11821 atcagcttta ctatctaatt taccaagata aaaaatataa gtactttgat aagtttcagt
    11881 ttcaattata ttttgtgtag ttacattaat atctaagtta tatttagaat ttactataaa
    11941 aaaaccattg tgttgtatta tatttatatc ttcaaataaa ttataaaaaa tattttttag
    12001 atattcaaag tctatatgag attggtaaat taaataaaag ttgcctttta aattatcaag
    12061 attattttta tctagaaaat caataacata aatagcatta ttgaaagtaa ctaaatggct
    12121 actagcatct aacttttggt tttcatatgg atagatattt atttttttat taagctgtct
    12181 ttctaaaaaa tcttttaact cttccataaa gtctccttaa aaataagatt atattcttat
    12241 cttatagcta aagtagtttc tttgtcaaat atgtgtactc tactattgtc aactgaaagt
    12301 gttaagtcat caccaacatt aattctgttt ttactgtcaa atctaattgt tatcgtattt
    12361 tctcctagtt ttaagtgagc ataagtttct gctcccataa gttcttttat ttcaattctt
    12421 gatttaaaac aagtatctgg attagattta ataaaagtat cttctacatg aatatcttct
    12481 ggtctgatac ctataacaac ttcattatta atataattgt cttttattaa atcatagtgt
    12541 ttttctttat tcaatttaag cttaatatgt tcattttgtg cataaatttc atcattttct
    12601 tctattaata ttacatcaat aaaattcatc tgtggtgctc caataaatcc tgcaacaaat
    12661 atattagctg gataatcgta tacatcttgt ggagttgcaa tctgctgaac tactccatcc
    12721 ttcattacta cgattctatc agccatagtc atagcttcaa cttggtcgtg tgttacatag
    12781 ataaatgtag ttccaagctg ttggtgtagc ttagttatct ctgttctcat agcagttcta
    12841 agttttgcat ctaagttgga tagaggttca tccattaaga ataccttagg atttctaact
    12901 attgcacgtc ctaaggcaac cctttgtctt tgtcctccag ataatgtttt aggtttttta
    12961 tttaaaagag gtagtaagtc taatatttta gcagcttctt taactttttt gtctatttca
    13021 tctttaggca attttctaag tttaagtgca aatgccatgt tttcgtaaac agataagtgg
    13081 ggatataaag catagttttg aaaaaccata gctatatctc tatcttttgg ttctatatca
    13141 ttgacaagtt tatctccaat gtatagttct ccttcagaga tttcttcaag accagcaatc
    13201 attctaagtg tagtcgattt accacaacca gatggtccta ctaaaacgat aaattcttta
    13261 tctttaatgt ctatatttat attttttact gcattaaatc catttgagta aagttttgat
    13321 atatttttta aaattacttc tgacataata tcctccttga tatttaaatt ttaattatat
    13381 agtatcaaat ttttttatta tattaaatgt gtaaaatgac taaatgtatt tgtttaatat
    13441 gtatatttag tttttagcaa agaataaaac taacagtaaa atatatttaa aaaattaaaa
    13501 aacaaaatta aatgtattat caaaaaatca ttttatgata tgttttattt ttatattaca
    13561 aatagagaat aatgaattat actagaaagt aggaggtgaa aatatgagca gaatttcaat
    13621 ttttatggaa tcatgtaatg gcaaatttcc aaatgaaaat tcaatgttgt cggtttcctt
    13681 tataaaaaat attttaaatg cagaaaataa agattttgct aaaaatatat ttaactatgg
    13741 ggaagaaaga aaaaacaata agcaaataaa ggatataaat acagccattt acataccaaa
    13801 tcttataaga agcaaaaatg agttacttgt tgatggagat ataatattca atataagttt
    13861 ttataattat tctatgttca gtaaattata caatggaatt ttaaaagtaa aggagctaga
    13921 atataaaggt tatagattta aaataaaaaa tataaaaata cataaagaac acgagataaa
    13981 agaaaatggt gttatattta aaactatgtc tcctataata gtaaagaata aagaaggtaa
    14041 atatttagat gtagaagatt caaattatat agaatgttta aactatatag ctaatctaac
    14101 tctggagagt gtaagaggta gtgggcttag aaagccattg gaatttatac ctcttaactt
    14161 caaaaaaaga gtgttaaaag aaaagattcg tggatttaaa gtgagagaat tttactatat
    14221 aaatgcttat gcaggaacat tttttttaaa aggagatatg gaagatttaa atgcactgta
    14281 taaaatggga attggatata gaaggacgga aaatgcagga atggttgata tattaaagta
    14341 gcgaggtgag agaaataaaa gctaaatttt atagatcagg tgatattgta agagatattg
    14401 gcattgttta cttttatgaa ttactaatgg atttaaaaaa cgaactagaa aaaaatgatt
    14461 ataagctaaa atttacttgt gagctaaata gaaattattt atctttagaa tctgcagaat
    14521 atatagaccc taagtatata tctgattata tattagaaaa tcaacttttt aaggtattta
    14581 aaaatgggaa aaaggaaacc ttagaaaaaa tatttagtaa tatagataat ttaacgtatg
    14641 taaattttat tgaagaattg gataaatctt ctgcaactgc taaacaaaag gaagatatta
    14701 aaaaagattt taaaaacagg aggtttccat atgttagaaa tagtggtaag tatggactaa
    14761 acacgagttt agaaaatatg gaaacaaatg taaaaagaat agtagatact gtaattaaat
    14821 caaatataga gatagatgaa atagataaac ttgatttgac acaatatgaa gaaaaagata
    14881 gtgtatgtaa tgtttgtaat ataaataaaa caacaaaact agatattgat ttaagagagc
    14941 gaaaggactc taagtataac tttttattta gaggtgcaga aaaatcaggc tttaaaagaa
    15001 gtggacaagt tgaaagtaat atttgttttg agtgtgaatt tttcaactta atgtgtcttt
    15061 tatatataaa tttaaaaaga ccaatggttt ttgcatatac gaatgattta agagaattag
    15121 catttttaaa tcataagata atgcttaaaa gaaaaatgta ttcagataaa tcattttata
    15181 aaaaactttt gcatgaaaaa ataagttcaa ttagactata tagatttgat attgttaaga
    15241 ataaaggtat aattctaaag tttgactcta ttatagagta taaagaatta ttaaaaaaaa
    15301 ttgaacttat agatattata gataattata atttctcaag ggagccagta aacactaaaa
    15361 atttaggtaa aaaaatgatt gataatggga atttatcaaa tttaaaagaa ttattacttg
    15421 ataatataag ttttttaaag caatcaactg gaacttctcg agaaatggat tttgtatcta
    15481 gctcatataa tatcggttta tatataaaat tgtgttggat tgtagatgga ggggaggagt
    15541 ataaaatgaa aaactatatg gaaagtaatt taatatattc aagagtaggt aaagacttat
    15601 ttaataaaat gacagatgaa tccagaagaa aaaatttttc tatgaaagtg attcaactac
    15661 ttaagtctaa tgatagaact cagctatttc aaactataat gcatgtgtta gtttctaatg
    15721 gaatcttaat aggagaaggg tttgtagaag gtctaatgca gagttctgaa ttagaattaa
    15781 atacgaatgt aggtctattt attcaagaaa tcatgaaata aaaaaggggg aaaatttaaa
    15841 atgaatgaaa aaagagtaaa aggagtaaca ttaactatac tgacagaaag cccagttcca
    15901 ctttcatatg accaagggta tggaaattat acaccaataa aaaaagaaca atatagagaa
    15961 aaaatacatg caaaaactag tatagccaca ataacatatg atttaagaag aatgctccac
    16021 caagaatatg gttggaattt aagtaatatt gtttttggaa aaaaaggaaa tatatatcca
    16081 tctattaaga aaaatgtagg atgtgtagat gaaaatggat tagagactga tgtatttggt
    16141 tatttgatac cacttaaaga taaaggttct ataagtaaag cttctccact tagaataata
    16201 ccttttaggt cattaaatcc atataaaggt tcaacacagc taataacaaa tagaggtttt
    16261 ttaagtagtg aatttggtag aaaatattat gatgagaagg aagaaaatga agtacctaga
    16321 gatgaaaact ttccaacatc acaagcatta gcaatagaag agactttatc agattactac
    16381 gtttatacaa taacattgga gcttgataga ataggagtag tagaagtaga agatggaaag
    16441 ttacttttac cagaagaaag aaaatttatg agtaaggagt taagagaaaa agcagtaaaa
    16501 gatatattag atgcaattac tgtgtttaca agaaacataa aacattcatc agtactatta
    16561 aaaccacttg cagtaatggg tggagctttt gataaagttg taccgttttt ttgggatgat
    16621 gtagattata atgctgatag tggtgagata aatttagagg gagttataga aactatagaa
    16681 agttatagtc ttaaagaaag taatacaata cttgctatca atgacagatt aaaaatttct
    16741 aataaaaagg aattaaataa gtttaattta agtaaatacc ctgtaaaaga gattaaaaat
    16801 ctagcagata gattggaaat tggagaagat aatatgtggt atttaaaaga gtaggaggtt
    16861 ttttgaatta tgaaagtatt acaatgtaaa cttaagcaac caactgctca ctatagagac
    16921 ccaaaagtat ttcaaaatga atatataagt actttaaatt taccatctaa gaccacaata
    16981 atgggaatga taacgtattt atgtgataga agattaaact ctgatataga tataggaata
    17041 attggaacac atcatcatag agaactagaa ttttcaagag gagagaacat tgatttttgg
    17101 aatgaatata caaatatgag aaaaggcaaa gataaagaaa agtttttgct tcaaggaaac
    17161 tactatgatt actataaaga acataaagct caaaatagca tattaaacta tgaagttctt
    17221 aaagaagtag aattgactat atttatttct tgcaaggatg atgaagaact tgaatttatt
    17281 agaaaaaagc ttgaaagtcc atgtaaatat gcaaatttag gaagaaaaga agattttgta
    17341 ataccaagtg aaaaagggtg ttttgtaaaa gaagttgcgt taaaagaggt tatacctatg
    17401 aatactcgtg atgctataaa agaaaatata aaattaaaga atacatatgt aagagttgac
    17461 ttaagagata aagagaatgt cgagactata ataaatcaag gtgtattgat tgcattgcct
    17521 cataaatata aagatttaga agcaaataga gatgatagag tttatgagtt ttgccattat
    17581 atatatgttg ataatgatgg tatatatcct aaaaatatta aggtaaatgt atgtattgat
    17641 acaaaagaag tttttacatg gctttaaatt attttgaaag ataggtgttt atcatgaaaa
    17701 atatcatgca aaaagaaata ttagctaagt catacaattt aagaactaat caacaagaac
    17761 aaacattagt tgaacatatt aaggatttat ttgaagtatt agaatctata ttagaactaa
    17821 atctatattc agataaagat gtagagatac taaaaatatg ttgtgctttg cacgatttag
    17881 gaaaaattaa ttcaattatg caacaaaaaa tggagattaa taataaaata tcgtatagtt
    17941 gttcagaaga agagaggaaa aagttagagt ctgacaaaaa atctttaaaa aagatagcaa
    18001 gacacaatat attttctgga gcatttttaa aaaatatact agaaaaaatg aacttgtcag
    18061 aagaagataa gttatatata tataaaagta taatgttaca tcatggaaac tatgaagatt
    18121 atatgaggtt aagtactagt aaagttcaaa aagaaattta tgattatatt gaaaaaggta
    18181 ttttagaaaa agaagatttt aatttggaag atatagaaga ttatataaag gagattttat
    18241 atgtagattt taaatttaat gaagatatat tggattatga ttacatagat aaattaagtg
    18301 aaagtatggt tatatacagt gattataaca atggtcaaat agaagattca gttttaaatt
    18361 atagaaagtt taagtatatt ttatataaag ggatgctgaa cttaatagac catagtgcat
    18421 caagtagaca gaaaggtata aaattttata acgattttac tgatgaagaa attgataata
    18481 tgattttaaa tgagatatat aagagtcagg gtaatttaga aaaaaataat atagagttca
    18541 atactataca aaaaaggttg agagaacttt ctggaagaaa tgttctgact gttgcattta
    18601 caggttcagg aaaaacagct gcagattata gaaagacttt taaaagaaaa ttctttttag
    18661 tgccaaataa aatatcagca gaaagttttt atagaaaaaa tatttttcaa aataaaaatg
    18721 atttagatac aagaagtagt aatgattaca ttggattact tcatggagat ataaacttat
    18781 attcagagaa tgaagataat ggagaacatg attttgtatt gacattaagg gatatagatt
    18841 tgagtataaa cttttgcaaa ccttgtgtaa ttgcaacagt tgatcagtta ttacttagta
    18901 tgtttaaatt tccgggatat gaaaaaatat tcgcagccgt aaaaaatgca tctataactg
    18961 ttgatgaagt acatttattg gaaccaaaga tgtttttgat tttgatatat tttatgcagt
    19021 ttgcatgcaa gtacttagat gttgattttc acttaatgac agctacactt ccaaaatcat
    19081 ataaagagca aatgataaac aagggaatta tttttcaaga agaaagtaat gaaaatgtta
    19141 ctgataaagg agaaatagtt tttattgaga gcaacaagga agaagagatt tgtgaaggta
    19201 aagatgtaaa ggtttctttt ataaaggaaa aagaaatcaa gtcaatagtt gaagatgctt
    19261 tagaaaataa acaaaaaatt cttataataa agaatactat tgattcagtc aatagaacat
    19321 atgagttttt aaaagaaaat ttatctgata agtatggtgg tgtagatata gatgttttac
    19381 atagtagatt taagttcaaa gataaaaaag agaaatatag taaaatatta aatggagagg
    19441 gtgatatttg gatatcaact caatcagtag aaatatcctt ggatttggat ttcaatataa
    19501 taataagtga tttagcaact atggatagct taatacaaag aatgggtaga tgcaatagaa
    19561 ataataaata tgaatatgga aacttttata ttctacctag tgaagataaa atttatgaca
    19621 acaaacttaa gagcacaact aaaaacatct taaaggacat attaaaaact aactctattt
    19681 ttacaatggg aattagaaaa actattttgg atgattacta tgataatagt gtagtcaaaa
    19741 aatattttga agagaatttt ataagttgtg ataaagaaat taagaatatt tatggtgtaa
    19801 ataaagaaat ttttgatgga ttggatttaa tttttaattt tgaaccttac aaaaatattg
    19861 ttgatagtaa gaaggaagca gctaaaattt ttagagatgt tgatgttagt tacaaaatta
    19921 ttctggaaga agatttttat aaggaagata gagagttaca acaagattcg attcaagtat
    19981 cagggtttat atttaataga ttatattatt atgggttaat aagcaaagta gaaggataca
    20041 tggtactaaa atctagtagt aagtttgagt ataatagtac tgtaggctta attttgaagt
    20101 gagcatatgt ttaaatataa tataccttta gacattgaaa atacaaaaag tactactgta
    20161 agctcactgt aaaaactatt tttttaaaag gaaaaataag ttgtgagata gagtgtttac
    20221 aagtgtatat agataataaa tttgaggttt aagattaact aagtgggttt caggtacatc
    20281 gcgaaaataa ttataagttg gagattttgt atgtttaaga ttaactaagt ggatttcaaa
    20341 tattgatata gtagatataa tagaagtttt attattaggt ttaaaattaa ctaatcggat
    20401 ttttaaatat tctgactatt atataaggat attattagct tgaatttaaa accaataata
    20461 taaaacaaca aaatattata tttatgatat aataaaagtt atggaaaaac aggaatatta
    20521 ctatagagaa gagaggtaaa cttatgaata attggataga agtaactata aaaacaacaa
    20581 cagaagcagt tgaacctata acgaatatac tatatgaaca aggagctgga ggagctgtaa
    20641 tagaagaccc aaaagacttt ttattccaaa agaaaaatga actagactgg gattatgttg
    20701 aagaagaagt atttaaaaag aatgaagaag atgatgttct tataaaaact tatgtttctg
    20761 aagaaaaaaa tgtgatggaa tttgtcgaaa taataaagca aaaagtttta ggattaaaag
    20821 attttggtat agatataggt gaaggaagtg tatcattgga ccaagtaaat gaagctgatt
    20881 gggcaaatgc atggaaagca tactacaaac caacaaaagt gggacaaagg gtagtagtaa
    20941 aacctacatg ggaagattat gctatgcaag agggggattt aatcatagag cttgaccctg
    21001 gaatggcatt tggtacaggg acacatgaga ctactagtat gtgcattaga gaattagaaa
    21061 agtatgtgaa taaagattct aaagtatttg atattggatg tggtagtgga atccttgcaa
    21121 tagcagcagc caaattagga gcaaaagaag ttgtagctgt agatttagat gaagtggctg
    21181 taaaagttgc aaaagaaaat gttcttgaaa ataaagttga aaaaagtgta tctgtaatgc
    21241 atggtaattt aaccgatgta ataaaagata aagcggatgt aatagttgca aatataatag
    21301 ctgatataat aaagatactt gcaaaagatg ttcaaaactt tatgaaagaa gatgctatat
    21361 tcatatcttc aggtataatt ttggataaag tagaagaagt taaagaaagc ttaattgaaa
    21421 atggatttga aatagttgaa gttcaaaaat taggtgaatg gtcagcaata gtttctaagc
    21481 ttaaaaaata agggatatgg tgacgtataa tggatagatt ttttgttgaa aaaaataata
    21541 taaatctaca agataaaact tgcactatag aaggtgaaga tgtaaaacat atttcaaaag
    21601 ttttaagatg caaattaggt gagaaacttg aaatatgtga caagaataat aatgagtata
    21661 tttgtgagat aatgaatata gataagagta tagttaattt agagatttta gaaaaagttg
    21721 atataaatag agaatcagaa cttaaagtaa ggctatacca gggacttcca aaagctccaa
    21781 aaatggaaat gatacttcaa aaattaactg aagtgggtgt agaagaaata atattagttc
    21841 aaactaagag aagtgttgtt aaagttgatg acaaaaaaga agataaaaaa tttgaacgtt
    21901 gggaaagaat aatttatgaa gcagcaaagc aaagcaaaag aggtaagata ccaaaattaa
    21961 gaggtgtttt aagttttaaa gaagctttag aagatatgaa aaaaaataat gtaaatattt
    22021 gcccttatga aaatgaaaga acagtttcaa taaaacatgc actaaaaaaa tgtgattcta
    22081 atatagatag tgttggaatt tttataggtc cagaaggtgg attttctgaa gaagaaatag
    22141 aacaaataca aaaaaataat tgtaatgttg tatcattggg gcctagaata ttaagaactg
    22201 agacagcttc tgttgtagca tcaacaatag ctttgtatga actaagtgat ttaggaggag
    22261 aaaaataaat tgaaaaaagt agctttttat acacttgggt gtaaagttaa tcaatatgaa
    22321 acagaagcta tgctagaact atttgagaaa gatggttatg aacaagtcaa tagtgaagag
    22381 tatgctgatg tttatgttat aaatacatgt acagttactc atatgagtga tagaaaatct
    22441 cgtcaatata taagacgagt taaaaagaag aatccagatg caataatagc cgttgtagga
    22501 tgttattctc aggtatctcc ggaagaaatt ttggatatag aagaagtaaa tttagtcatg
    22561 ggtacaaatg atagaagaaa gattgttgaa gaaattaaaa agataaattc aagtaagaaa
    22621 gttagtacag ttgacgacat aatgaaagtt aaagcttttg aagaaataga aatcagccaa
    22681 actaatggaa agactagagc atttatgaaa atacaagatg gatgtgacag attttgtact
    22741 tattgtatca ttccttatgc ccgaggacgc gttagaagta gagatattga tagtatagtc
    22801 gatgaagtga aaaaattggc taataatggc tataaagagg ttgtattaac aggaatacat
    22861 gttgcctctt atggaaaaga tttaaaggat agggatatta aacttcttga tgtaataaaa
    22921 caaataaacc agatagaaaa aatagaaaga attaggctta gttctgttga accaatttta
    22981 tttacagatg aatttgtaaa tgaagtttta aagatggata aagtttgtcc tcattaccat
    23041 ttatcacttc aaagtggatg tgatgaaact ctaaaaagaa tgaatagacg atacacaact
    23101 ttagagtaca aaactattgt agatagattg agaagtaaaa tgccagatgt ggcaataact
    23161 acagatgtaa tagtaggttt tcctggagag acaaatgaag agtttaaaaa aacgtacgag
    23221 tttttaaaag aaatagagct ttcacaaatg catattttta aatattcacc aagaaaagga
    23281 actccagctg caactatgga aaatcaagtt gaccctcaaa tgaaacactt tagaagtgaa
    23341 caacttttaa atttaagtaa agtaaatttt aataaatttg caactaaatt tatcggccgt
    23401 gagttggatg ttttgtttga acaaaatata gaaggcaata aatatgaggg attaacttca
    23461 aattatataa gagttgttgt tgaaagtgac aaaaatatac aaggtcagat attaaaagtg
    23521 aaaataaatg atgtaaaaga tgaatatgta gaaggaattt tgctataaca tgtagaaatt
    23581 ataatattta taagatagga ggtggaaaga atggattgta ttttttgtaa aatagcgaac
    23641 ggagaaatac cttcaactaa agtttatgaa gatgatagag tcttagcttt taatgacttg
    23701 aacccagttg ctccatatca tatattagtt gtacctaaaa aacattatga tagtttaatt
    23761 gatattcctg ataaagagat ggacattgtg tcacatattc atgttgttat taataaaata
    23821 gctaaagaga aaggttttga ccaaactgga ttcagagtca taaataattg tggaagtgat
    23881 ggagggcaag aagttaaaca tttgcactat catattttag ctggtaaaaa gcttcctaat
    23941 tacgaagcgg gacaaaacta aactaaatta ttgaaaaatt gagttccttc ttgataaaaa
    24001 tacttgataa aagtaaaaat ttagtttata ataaacaaag tgttaggttg taatgcatat
    24061 tatgcaaaaa gaacatagtt acagtcccag cataattgcg ctattggagg gagggaaaaa
    24121 gaaatgtcag aagtaagagt tagagagaat gaaacattag acagcgcttt aagaagattc
    24181 aagcgtcaat gtgcaatgtc tggcatcatg tcagaagtga gaaaaagaga gcactatgat
    24241 aagccaagcg ttaagcgtaa gaaaaaagct gaagcagcaa gaagaaaaaa cgctaagaaa
    24301 tagtagtaaa taagaataaa gaggtgaagg ggatgtccct taagcaaaag ttacaagagg
    24361 atttgaaatc ttcgatgaaa aacaaagata cagtgagaaa atctgtagta actttaataa
    24421 gagcttctat aaagcagtat gaggttgata atagggtcga gcttgatgaa gatggaatta
    24481 tcgatgtaat agcaaaacaa ttaaagcaac gtagagatgc attagttgaa tttgaaaaag
    24541 ctggaagaga agacttaata aaagaaacag aaggtgaaat tgaagtttta aaagagtacc
    24601 tacctcaaca attaagcgaa gaagagttag aagaaattgt aaaatctact atatctgaag
    24661 taggggcaac ttctatgaag gatatgggaa aaataatgtc agttatccaa ccaaaagtta
    24721 aaggaagagc tgacggaaaa cttataaata agttggtaaa acaaaactta caatagattg
    24781 atatagccta gagagaaatc tctaggcttt ttatagtttt tgggaataac gagtcatatt
    24841 tgagcatatc tataatcaaa gaaaattttg aaagaagggg aaaaatttga ttatatcagt
    24901 aaaagagatt aggaattttt tgataaacat atttatacca ctaataatag gttacttaag
    24961 tagcatctta acaatgatta tcagtggaac agatatttca acctattatt tacaactcac
    25021 aaagccaagc tttgcaccac cagcttttat ctttcctata gtttggacta tattgtacat
    25081 attgatgggt atatcttcat acctaatatt aagaaagggt tacaacttac ctaaagtaag
    25141 agatgcaatt ttttattatg gattacaact tgtattaaac tttatttgga gtatactatt
    25201 ttttggattt ggacttagat ttacagcttt gatagatata ataataatga ttttggtttc
    25261 tataataatg atttcgaagt tttctaaaat agataagaga tctggataca taaatttgat
    25321 ttatttaatg tggcttgttt atgcaggatt tttgaactat tttatatggt ttattaataa
    25381 atagaatgta aagattttgt aaattaccct gtacttttaa taatatcata acaaacgaaa
    25441 aataaataga ctattaaaaa taatcatttt catatacaat aatattaatt taaatacaat
    25501 aaatttataa aaattgtatt taaagattaa catattaaag tattagaatt ggaaaggctt
    25561 gaagggagag gtttttatgc aaataatagt atctgggaga caaatgaaat taactgacgg
    25621 aataaaagga tacgtagatg gaaaattaag taggttagaa aaataccttg atcctgaatc
    25681 agaagtgaaa gtaacagtaa gtgcgaaaaa ggatagacaa aaagtggagg ttacaataat
    25741 tcctattaac ggtcaaataa taagagcaga agatgtagaa gatgacttat atgcagcaat
    25801 tgatattgtt tgtgacaaat taagtagaca agttgtcaaa tataaaacta aagttaaaga
    25861 caaagttcaa aataataaga gcataagatt tgaaaatctt gactttatag ataatagcag
    25921 tgaatttgat gattatgatt atgatgatga agaagatgaa aatatagtaa tagaaagaag
    25981 aaagaaattt aatgtaaaac ctatgagttc tgaggaggcg atacttcaaa tggaactagt
    26041 aggacacaat ttctatatgt ttagaaacca agataatttt gaaataaaca tagtgtataa
    26101 gcgtaaagct ggtggatatg gtttaataga acaagattaa taaaaattgt atacgtttag
    26161 attttatata agaaaaaata aaaaggtaat catgttgatt ttttatcaat atgattacct
    26221 ttttcttgtt taaataatat attagatatt aggtatttat tatataaaaa ttttaaaact
    26281 aatctgttac aacatcaata aagtgcataa atacctattt caagcataaa attaattaag
    26341 ggggtaatgc ttatgttaga aatatccact gatttacaag taaatcaacc agttattacc
    26401 gttacaagta atacgtttat tagtatagaa aattatctat caatattaga atatgaagtt
    26461 gatttaataa gaataaagac taaagttaaa acaattaaaa tatctgggga taaactttca
    26521 cttaagtata ttactgatag tgagataggt ataaaaggga ttatctacaa tgttgagtat
    26581 gttgattagg aggagataca cttgataagt tttataaggg gatactatgt tatagttgtg
    26641 gaaggagtaa gactcgaaca atttttaaat catcttataa gaaatgggat aagtgtttac
    26701 aatgtaacta gaataaaaaa tactaaaatg gagtttcata tagatagaca agatataaaa
    26761 gaatttaaga atgtttatag aggaagtaag tttgatataa aggtaaagca aaaaactggg
    26821 gtccctttta ttatcaaaag agtttataag cacaaaggta tgtggatttg tgctcttgtt
    26881 tctttatttt tattgatgtc tacatcacag tttgtgacag atgtatatat acaatctcct
    26941 gaaggtataa aaaaagaagc tcttagaaat gagctttata aggttggagt aagaccagga
    27001 gtctataaga agagtattga tagaaaagaa gttagagacc atatgatgtc aaaatttaat
    27061 gatgtggcat atttatctat caatgtaaaa ggaacaaata tatttgttac tgttacaaaa
    27121 aaggcagaat ccctaaaatc tacagaccaa tcaaattatt gtaatgtaat tgctttaaaa
    27181 aatggtataa tagaaaaggt aatccctaga agtggtaaat cagttattaa atctggagac
    27241 atagtccaaa agggagatgt cttattaaat ggagctaata ccaagtcaat accagaagta
    27301 tgggcaagta ctttttatga gtccacaaaa aaggcaagtt atgtagatac tgtaaataaa
    27361 aaaactggag aaaagaaaaa tatatataca ctaagttttt atgataaaga gtttacaatg
    27421 agaaaaaata taaaatataa agattatgtt gttgaaaata aagaaaaaaa actatcaata
    27481 ggaaactata cttttccaat aaagataaaa acgagtactt tttatgaaac aaaaaaggtt
    27541 gaagtaaaaa ggaataaaga agagttaaaa aaagaattat ctgaaaaagc tttaaaagag
    27601 ttagaataca taatcccagc ttcggctaga ataatagatg taaaacataa ctttaaggtt
    27661 aataaaaata tgttagaata tttaataaca gttcaaacta gtgaaaatat tgctaaaatt
    27721 tatcctctta gtaagtcaga agcagaaagg tttataaagg aagaaagtaa accagatgaa
    27781 ggtgaagagg aagttccttc caatccagaa aaaagaccat taaatgatat aagaaatgag
    27841 tttgatgagg ataataagga taataaagac caaaacaatt ctgatgaaaa taatagtaat
    27901 caaaatagta ataatagtca aaataataat agcaataaca actaataaaa ttaaacttaa
    27961 aatcttagga ggactaattc aattgataat acaaaagaaa tttacaatag cagatggtaa
    28021 ctttgaaaga gagttatttg gcaactttga tgaaaatgta aaattaatag agaagacttt
    28081 aaatatagat gtaatactta gagaaggcaa tataatttta attggagaag aaaaaaatgt
    28141 agattctgca ttaaaactta tgaatgaatt acaccaaact gtatcaaatg gtaagcattt
    28201 agataagcag agtatttctt attcattatc tcttttgctt gaaggaagtg aacaaaaaat
    28261 aaaagaactt gaggggacaa tcgtcataac tcaaagggga aaagctgttc aacctaaaac
    28321 tttaggtcaa aaagaatata taaaacttat agaaaataat gatataactt ttggtgttgg
    28381 acctgctgga acaggaaaga cttatcttgc ggttgctatg gcagtaaaag cttttaaaag
    28441 agatgaagtt agtagaatta tacttacaag accagctgtg gaagcaggag agagtctagg
    28501 ttttttacca ggagatttaa aggacaaagt tgacccatat ttaagaccac tatatgatgc
    28561 cttatttgaa atgttgggtg ctgataaatt taataagtat ttagaaagag gtactattga
    28621 ggttgcacca cttgcattta tgagaggtag aacacttgat aattcattta taatattgga
    28681 tgaagctcaa aatactactt ctgaacaaat gaaaatgttt ttaactagac ttggatttgg
    28741 ctctaaagct gtagttacag gagatgtaac tcaaacagat ttaccacaaa ataagaagag
    28801 tggtctaata caagctacag agattcttaa aggtgttcca ggtattgggt ctataatgct
    28861 aacagataga gatgttgtaa gacatgagtt ggtacagaga ataataagag cttatgagaa
    28921 gcacgacaaa agagaagaat ttaaaaaaga agaacgtaaa aaagcgaaaa tgcaggaaaa
    28981 gactttcaaa agaaagtaaa agtgtagtaa tatagatata tagcattatt aatgaataaa
    29041 aagtaggtgt agtgaatgga tttgatacta gatgatagac aagataaatt agaagtaagt
    29101 gaggagttaa ttgaaaagat aaaggatata atcatagaat gtttagatta tgaaggatat
    29161 gatgataatt atgaagtgag tctttctttt gtagataata aagagattca tgaattaaat
    29221 agagaatata gaggagttga tagagtgact gatgttttat catttcctct tttaagtgat
    29281 gattttgagg atgttgagtt agaagaagaa tccctaggtg acatagtagt atctcttgaa
    29341 agagccttag aacagagtat agagtataac catagttttg aaagagaagt atgtttttta
    29401 atatgtcata gtatgtttca tcttttaggt tatgaccacg atacagatga aaatacaaaa
    29461 gaaatgagag aaaaagaaga acacatatta aataagttaa acataacaag ggagtagttt
    29521 ttatgaaacc agaaaaaact cgtcaaggta taattaaagc atttaatgca gctatagaag
    29581 ggatattgta tacatttaaa tttgaaagaa atatgaaaat acattattta ggttcagttg
    29641 ctgttcttat aataagtttg ttttttaact tttcaaaatt agaaatgata atgttactta
    29701 tgtccatatg cttagttgta gttgctgaaa tgtttaatac agctatagaa aaagctgttg
    29761 atttagtaac tgatgaatat catgttcttg ctaagatagc aaaagatgtt gcagctggag
    29821 gcgttctagt tgcagcacta aattcagtag tagttggata tattttgttt tatgataaat
    29881 tgacagatat atctggaata ttaatttata aaataagaga atcagaatta catataacct
    29941 tgatatgtat attattggtt cttatagctg ttgtagttgt aaaagcattg acttctacag
    30001 gtactcctct aaaaggagga atgccaagtg gtcatgctgc cttagcattt gctatagcaa
    30061 ctgcaattac acttatgact gaaagagttg ttgcctctac tcttgcatat ataatggctg
    30121 tattagttgc ccaaagtaga attgaaggaa aaatacatac cttttgggag actattgctg
    30181 gagctttgtt aggtgtgttg atagctatat tagtatttca gcttggaatg ttctataatt
    30241 aaaataaatg tacataaaat atttaaaata aaacaaatct gtgctaatta aatttttatg
    30301 atataatgta gagtattaaa taaaaataac ttttaattat tgtatacagg aggagttgtt
    30361 gtggataaca tagaattgtt aaggttggca gaagatgcca gacaacattc ttatgctcct
    30421 tactcaggtt ttagagtagg tgcagctctt ttaactaaga gtggtaaagt ttatactgga
    30481 tgtaatatag aatgtgcatc attaggtgga acaaattgtg cagaaagaac agctattttt
    30541 aaagcaatat cagagggtga taaggatatc tataaaatag ctatagcaag tgataactca
    30601 gaaaataatg agcaaacata tccatgtgga atatgcaggc aggtaattat agagtttggt
    30661 tctgatataa aaataataac gggatatact aaaggagagg tgtttgagca tagtataaag
    30721 gatttgttgc caaactattt ctctggaaat gatttaaaat aaatttaaaa gtataaataa
    30781 atttaaaagt ataaataaat ttaaaagtat aaataaattt aagtaattaa aacaagaaga
    30841 taaaaagtta ggagacagtt aatgttcaaa tcaggttttg tcagtatagt gggtagacca
    30901 aatgtaggaa aatctacttt aatgaataat gtagttggag aaaaaatagc tataatgagt
    30961 gataagcctc aaactacaag aaatacaata caagcagtat atacagatga agaaatgcag
    31021 atagtattct tagatacacc aggtattcac aaaccaaaaa ataaattagg tgaatttatg
    31081 gtaaaggcag caacagaagc ttttaaaaat gtagatttaa tattatttgt agttgatgat
    31141 tctaaaaaaa taggtcctgg agatagaaag ataatagagg atttaagaag tgttaagaca
    31201 ccaataattt tagttgtaaa caaaatagac caactagacc aaaaagatga gctatttgat
    31261 ataatcaaaa tgtatgatag agaaggtatt tttaaagaaa tagtaccaat atcagcatta
    31321 aaaggaaaga atacggatac cttaataaaa gttatacaaa attatttaga agaagggcca
    31381 aagtattttc cagattatat gattacagat cagccagaaa gagtattaat agcagaactt
    31441 ataagagaaa aagttcttca ctatcttaat gatgaaatac ctcatggtgt agctgttgaa
    31501 attgaaaaaa tgaaagcgag aaatgataag gaaatagtag atgtatctgc tgtaatatac
    31561 tgtgaaagag attcacataa gggaataata ataggaaaaa atggtaggaa actaaaagga
    31621 ataggtaagt cagcaagaca agatatagaa ttgcttttag gttcacaaat aaatcttcaa
    31681 ttatgggtta aagtcaaaga aaattggaga aatttacaaa attatataaa taattttgga
    31741 tataatgata aataaaggtg ggttatatgg ataggaaact ggatgcttcc caagatttat
    31801 tatatgaagt aaaatcatta attgataata ataaagtatt ggagttaaga gaattaatag
    31861 aggaatatca tataattgat atattcgata taatggaaaa tttagaggaa gacatgaaaa
    31921 ttcaattatt tgaagtactt cctttagata tggcatcttc tatattagaa gaaggtagtg
    31981 tagagttttt tattagtatt ttatctaaac tggatgtaga acactcgaaa aatatacttg
    32041 aacttatgtc tcttggagat atggcagaca agttgagtga acttgaagaa gaagaaagag
    32101 aacacataat aaatcttttg aatcaagaga atgccgatta tgtaaaagag ttactattct
    32161 atgatgaaga ttctgctggt ggaacaatga ccactggata tatttctata aataaagata
    32221 tgacagctct tgaggctata gaccatatga gagaagaagc tgaagaagct gaaactattt
    32281 attatatata tgtggttgat gatgaagaaa aactagttgg agtattgtca ttaagagaat
    32341 taataatagc tagagacgca aatatagtag aagatttgat gagtgaaaat ataatctctg
    32401 tttatgtaga tgaagataga gaagaagcag taagattagt atctaaatac aatttaatag
    32461 caattccagt agtagacaga caagaaaaat taaaaggaat aataacagta gatgatataa
    32521 ttgatgtaat ggaagaagaa gcaactgaag atatgtataa atttgcagga agttcagaac
    32581 atgaaagaga agttgctgaa aaagaaaacc ctacattgag agagcaaata atatcagcac
    32641 ttagaggacg attaccttgg ttaattatta ccttagttgg agggttgttg gcttcgttaa
    32701 tactttctaa cttagactat ataatgaatc ctgtatatgc tccattagta ttttttatac
    32761 ctgtagtaat tggtatgggt ggaaatattg gaactcaatc atcatctgtt acagtaataa
    32821 cattatctaa taaggattta aattttagca atgtggttag agaaggtatt gtaggtatta
    32881 ttacaggtct tttgtgtagt ataataacag gtattgtaat ttactttgtt atgagaaagt
    32941 tagacattgt attaattgtt tcaatatcat tatttataaa tatggtttta ggtgcaacaa
    33001 taggtgcgtt tatgcctgtt ttattaaaaa aaatggatgc agacccatct acagtttcat
    33061 caccaattat atctacagct cttgatataa ctggtatagc agtttacttt ataataacaa
    33121 cggcattatt gtcaaaaatt gtttaataac tttatgtatg atttatcctc ttcttactaa
    33181 aaatataagt ataaatgtaa gaagggggtt ttttaaaaat gaacaatatc agttgggaag
    33241 tttttaaaaa aacaggtagt atagatgcat atttatattt ctgtgattgc aaaaacatac
    33301 atgaagaaat tgaagaagta agggagaaaa aagaagacga tgataatcct gaacacccag
    33361 gggatagtac ttaaagctat aaggtataag gaaagtgaca taatacttac actatttaca
    33421 agaaagcttg gaaaagtatc tgcaatagca aaaggagcta aaaaaaataa gagctctttg
    33481 ctttcatcat cacagttatt ttcttatagc aattttacct taaaaaaaca aggtaatatg
    33541 tacaaggtta ctcaaagtga aataataaaa agtttttata atatatccta tgatatagag
    33601 gcattttctt atgctacata tattacaaaa ttagttgaaa attctatact tgaaaatcag
    33661 actaataata ggctatttat attacttgcg cagactctgt atttgtatac acaggataat
    33721 acagacaata ggtttataac agcagcattc gagttaaaat ttttagacta tataggattt
    33781 aaacctatag taaataaatg cattaattgt gaatgtaaaa ttttacaaaa ttctgtgttt
    33841 aatatctacg aaggtggtat actatgtagt aagtgtagta aactttttga taataatata
    33901 aaattagact taacaactat aagtcttatg gaatatgtat taagaaatga tattttaaca
    33961 tgtagtaaag ctaaagtatc aaaatatata acacatgaac ttgagaatat tctagacaag
    34021 tatttgaaag tttatgttga taatattaat tttaaatcat tacacgtatt gcaaagtgta
    34081 aaaaataata agggagtgga taatgatgag tagtaatata actattgaaa tggttgattc
    34141 agtctttgaa agagttccag gagcaactta tgcagaagca aaagaagcat tagtaatgtg
    34201 caatggagat gtaattgagg cagtaatata tttagaaaat aaaaaaaata cttgtaattg
    34261 taaagcaaaa tctgctaaag aaactatgga agaagtattt ggcaaagatg gagaaaatat
    34321 aaagtttcaa ttaaaagagc ttcttagaaa aagtagtgta gtgagaataa tagttgaaaa
    34381 agatggaaaa actatgatga acattccttt aacagttgga gttgttggat tagcttttgt
    34441 accattagct actttagttg gattatcagc tgctgttata agtaaatatc gtataaaagt
    34501 tcaaaatgaa gaagatggag aaattgtaga tttaggtgaa ttgaatgaag aaaaacttca
    34561 cgttttgaag aatatgataa ctaatgcagc aaaagatgtg aaggatgtag tagttgacaa
    34621 aaaagaagat gacaaagatg taactgctga ccttatgaaa gaagaatctg aaaagaataa
    34681 agaagacgaa gacgaaaata aatagatata aagtgacttt taaaaaatga agagaagata
    34741 attataagaa ttatcactaa cattgacaaa ttttatagaa tttgatattc taaaagttgt
    34801 agaagaacta ttaaaatagc ctttcgtgta gacgagaggc tttattgtta taggagggat
    34861 ttttatgaat tttcaagaga tgatactggc gttgcaaaaa tactggtcaa agcaaggttg
    34921 tatcatgatg caaccttatg atattgaaaa aggtgcagga actatgaatc ctaatacttt
    34981 tttaagatca ttaggacctg agccttggca agtatgttat gtagagcctt caagaagacc
    35041 agcagatgga agatatggtg aaaacccaaa cagactatac caacatcatc aattccaagt
    35101 tatactaaaa ccttctccag ataatataca agaattatat ttggaaagtt taaaagagat
    35161 tggaattgac ccaagtgagc atgacataag atttgttgaa gataactggg aagctgctac
    35221 agttggtgct tggggacttg gatgggaagt ttggctagat ggtatggaaa taactcaatt
    35281 tacgtatttt caacaagtag gtaatattga atgtgagctt gagacaggag aaattacata
    35341 tggattagaa agattagcta tgtacattca agaagttgat agtgtttatg atttaaaatg
    35401 gaatgataaa ataacttatg gtgaagtatt taataaagct gagtatgaaa actcaatgta
    35461 cgcatttgaa ttatgtgatg cagatatgtt gtttaatctg tttgatatat atgaaaaaga
    35521 agcattaaga cttatggaaa atggacttgt aataccttca tatgactatg tgttaaaatg
    35581 ctctcatgca tttaatacat tggatgcaag aggtgcaata ggagttagtc aaagagcttc
    35641 atttataggt agagttagaa atatggcaaa gactgttgca gaaacttttg taaaacaaag
    35701 agaagaaatg ggattccctc ttttaaagga cggtgacaaa taatgaaaaa ttatctttta
    35761 tttgaaatcg gtgttgaaga aatgccatca agatttgtag gcagtacact agaacaatta
    35821 aaaaacaatc ttagtaaatt atttgatgaa aatagaatag cttttgataa aataaatgcg
    35881 tatgggacac caagaagact tactttagta gtcgaaggat tgagtgatag acaaaatgat
    35941 ttagaagagg aaataaaggg tcctgctaag aaaattgctg ttgatgcaga aaataattta
    36001 acaaaaccag cattaggatt tataaaaagc aaaggattaa gcgaatctga catatatttt
    36061 aaacaagttg gaaaagaaga atatatattt gcgactataa agcaagatgg aaaagaaact
    36121 tcagaagtac taaaagacat attaccagag actataaaat ctgtagtatt cccaaaagct
    36181 atgcgttggg gaggaaaaaa tcttaaattt gcaagaccta taagatggat agttacattg
    36241 ttaaatgata aagtattaga gtttgattta gaaggaataa tatcttctaa tgtaacaaaa
    36301 ggtcatagat ttttaggtga aagtacaata gaagttgatt ctatagaaga ttattttgaa
    36361 aaattagaaa aaaattatat agttttagac caaaacaaga gaaaagaaat gataagaaaa
    36421 caatgtatag aagtagcaaa ttctttaggt ggagaagttg aatttgatga agatttactt
    36481 gaagaggtaa cttatttagt tgaatatcca actgcttttt atggagaatt tgatgtggat
    36541 tatataaaac taccaaaaga agttgttata actcctatga aacaacatca aagatatttt
    36601 ccagtactta aagaaggaaa actgttacct aactttatag ctgttagaaa tggtgattct
    36661 tacagaatag acaatgttaa agctggaaat gaaaaagttt tagaagcaag acttgcagat
    36721 gctttatttt tctatagaga agatactaag agaaacttag aaagctacat agaaaaatta
    36781 aaaactgttg tattccaagt aaaactagga actatttacg acaaaacttt aagacttgaa
    36841 aaattaagtg ctgatatact tgatagttta ggtttagtag atgaaaaggc agatactata
    36901 agggctgcta aattatctaa ggcagattta gttactggaa tggtaggaga atttgatgaa
    36961 ttacaaggtt ttatgggaaa agaatacgca aaagttggag gagagaatga tgttgtaagt
    37021 gaagctattt ttgaacatta tcttccaaga tttgcaggag atatacttcc taagactaat
    37081 gcaggggttg ccttatcaat agctgataag ttggattcaa tagcaggttt ctttgctata
    37141 ggaatacaac caacaggttc tcaagaccca tatgctttaa gaagacaagc tttaggtata
    37201 cttagtatac ttatggacag aaaagttgct gtggatataa aagtacttat tgaacatgct
    37261 ttagataatt attctgaatt agattttaat aaagaagaag ttgttgagca aataatgagt
    37321 ttcttcaatg agagagtaaa aaatctattt aaagatttag gaataagata tgatgttgtt
    37381 gatgctgttt taagttctga tataaatgat gtttctgata tgcatatgag agctttagag
    37441 cttaataatt ggctagaaaa agatgaatta gtggagatgc ttactgcatt taatagagtt
    37501 tctactctag ctcaaaaagc agaaagtgat aaaattgatg aatctttatt aaaagaagat
    37561 gctgaaatta aactttacaa tgaatttaaa caagtaaagg taaaagttaa tgaattatta
    37621 aaggataaga aatatggtat tgctttagat gaatttgcat ctttaagacc agtagttgat
    37681 aatttatttg atacagttat ggttatggat aatgatgaag ctattaagaa caatagactt
    37741 gctttactta aacaagtata tgatactatg ctagaaattt gtgatttatc taaaattgtt
    37801 tataaataaa atttaaacta tttataagaa ataaggctgt ctcaaaatag agatagtctt
    37861 atttttcatt gttgagatga tgaaaatata tttgatttca tagaaaaaga gtgtctcata
    37921 aactaaaaag ttcattttga gacacccatg ttttttgtaa gtaaatataa taaattatat
    37981 tttatactta tcagttattt tgtttaaaat attatcattt gaatttaccc attcataaaa
    38041 attgcctgat gatgcgtccg atattttata aagcatttca ggaatatcac tagctttaaa
    38101 atctccaagt gattttccca atctagtctt acctatttca aaactgcctc caacaaataa
    38161 ttcaaatgca tctgtagata taccatcaac attcttcttt ttaccacata aacctatgct
    38221 accaacttga tgaacaccac atgaatttaa acatcctgat atatataact taggtgcttt
    38281 atttaaaatt tcttcattat tttgtaatct aaaataatct atgatttcat gtaacatttt
    38341 ctgactattt tgtatgccca tttgacaaat tggaacacct atgcaagata tactttgttc
    38401 taattgagaa ttacaactaa tagttttact tatttctaat attctttttg cttcatttcc
    38461 atttaaattt aaaatatata atccctctgt cattcctagt ctaatcatag gattttcaac
    38521 attatctaat tctttaagta aagtacttaa atcctttgtt aacaaaatac ctccaactgg
    38581 atgtatatat acagtgtata aaccatcctg tttttgaggt attagtctag aatcttgtat
    38641 atctatttta actccaggtt tagagtaatc tatttcttca atattgagtt caagactacc
    38701 attttctttt tctaatttat agtattcttt aaatttttct aagaatagtt cttcaccaag
    38761 tgattcgacc atatatctaa ccctagctct atttttattt tcataatttc cataatccat
    38821 aaagaattta atcatacctt caacacaata taaggcgtct ttcggcttta taagttcatc
    38881 aagttctaaa gcaactttgg gctgtttacc tagacctcca cctaagaaaa ctctgaaata
    38941 tggttcatca tttttcaaag tagcaacaaa tcctaagtct tgtatactac aatgagcagt
    39001 atctgtgtaa caattagaat aagaaacttt taattttcta ggtaaatggt atgtagtagc
    39061 atttttgata aaatatttat cagtagcaac tgcatatgga gtaacatcaa agacttcact
    39121 agggtcaact ccagataatg gagataatcc gacatttcta ggataattac caccaccacc
    39181 tctagtgaat atatcatttt ttattccttc ttccatgata tcaacaattg aatttataga
    39241 taaatcgtgt aattgtatag cttgtctagt tgttaagtgt atcttatcta agttgtgttt
    39301 aatagctatt tcatagattt tattaagttg atactgagat aaaactccag cagatactct
    39361 aagtcttatc ataaaagatt ttttgtctct ttgagcataa acaccatatc caccagaaaa
    39421 tcccttatat tgcattttat ttatttctcc atttaaaaat tttgaagaat attctttaaa
    39481 attaggtagt tcatttaaca atatcttttt aaaattatcc attatttcac ctcattgtta
    39541 gtcttgtata aaaatatatc tattgtataa tagatatata tattattatc tagtcaggat
    39601 aaaaatataa cagaataatt ctattaaaag taagaataat aaggacatag tgagtatttt
    39661 gtttttattt tacaaattaa gtataatatt tttgttttat aaaatataat taagataaat
    39721 agataatttt gtaattttaa tatataatat ttagtagagt gtgggagtag cacttaatat
    39781 ttgcaggagg agtttttgta tatgggagaa ataataaatg cattagatag agccctagac
    39841 ataattttgc tgttatatca tgaaaagaga gaaatgggaa taactgaaat aagcaaggct
    39901 atgggagtat ataaaagtac tgtacataga actttggtta ctcttgaaaa caaaggtttt
    39961 gttatacaaa atgcagagaa tggtaagtat tggctaggaa taaatttata tgcaataggt
    40021 atggttgtgg gagaaaaaat gtcattgact gaaatagtaa aaccatatac gaaaaaatta
    40081 aatcaagaat ttaacgaagt agttaatgta tctatattag aagaaagagc tcaagattct
    40141 ccaagaagta tcataataca taaagagtat ggttcaaatc aattactttc agtaaatcca
    40201 tccgttggtt caagtagtga atgttattgt tcagcagttg gtaaatgtct tatggcattt
    40261 aatgattcta tagattttga aaaatataga aaaacaccaa tacacaagta tacagaacat
    40321 acaattgata attgggatga tatgatgctt tttttagcaa aaataaaaga acaaggatat
    40381 gctatagatg atgaagaact agaacatgga ctaacttgta ttggagcacc tatcttagat
    40441 aaaaataata aagctattgc agccataagt ttgtcaggtc caactataag aatgagagaa
    40501 ggggactttg agtataagat taaaagagtt atagaaactg caaaaagtat atctgaactt
    40561 tttagatgat ttttaatctt gataataaaa ataggctata tttaaattgt tatttgtaaa
    40621 tatcaattta aatgtagcct atttttcttt aatctaaaat taaatattct taaaatttaa
    40681 aatgttattg aaatatataa gcgaatgtgt tatcttttaa ttaagcaata aaaatagaac
    40741 aaggttctat actatagaac aaaattgatg catatatagt atttatacaa aatataaata
    40801 ttatatattt aaaattaagt aaaaatatta cataaagggg agatttgaga aatggaaaaa
    40861 gtcaagttga gtgttgaaag atgtaaggga tgctatcttt gtattgaagc ttgtaaaaaa
    40921 gatgcaataa gtctttctga ctacaaaaat aaaaaaggct ttgtaactat taaagtcgat
    40981 gaagaaaaat gtattcaatg tggcgcttgt tatacaatgt gccctgattt agtatttgag
    41041 atattataaa ttatttttat tagaggggag aaaaggtatg caaagtttat taattaaagg
    41101 aaatgaagct ttagcagaag gtgctatacg tggtggctgc agattttatg caggttatcc
    41161 aataacacca caatcagaaa tattagaaat gatggcatgg agacaaaaag aagttggagg
    41221 agtatttatc caaggtgaat cagaaatagc cagtgtaaat atggttatgg gagcaagtgc
    41281 acttggagca agagctatga cttcttcatc tggtccagga ttttcattaa aacaagaagg
    41341 tattgcatat tgggtatcag ctggtttgcc agcagttgta gcatgtgtgc aaagatatgg
    41401 tataggtgat ggatttatag gagctggtca agataattat tggcaagcag taaaaggcgg
    41461 tggaaatgga gattatcatt taatcgtgtt agcacctaat agtgttcaag aaaatatgga
    41521 tatggcatat gaatcttttg aattggctga aaaatatatg catccagtac ttatactttc
    41581 tgatgctaca ataggtcaaa tggtagaacc ttgtatagca ccaccaatga aagaatacga
    41641 tatggataaa gctccatggg ctgcaaaagg aacacctgta ggagaaaaaa ataaagtaat
    41701 aactgatata acatattttg aagaccaaga tacatggcaa aaagggtata tagaaaaaat
    41761 gagaaaagtt caagaagatg aacaaagatg ggaagagata gaaatagaag atgctgaagt
    41821 ggtatttgtg gcatacggta tttcatcaag aatagcagaa ggtgcagtta gagatgctag
    41881 agcaaaagga atgaaattag gtctaataag accaaaaaca ttgtggcctt acccaagaaa
    41941 agcatttaag aaattaagtg attcattgaa gggacttgta acagttgaaa tgaacatgat
    42001 ggcacagatg aaggaagatg taattatagc atgtgataat agatttccag tatattcagt
    42061 agcaacagct caatatatgg cagaagtaaa tcaattaata gattttgctc aacagattat
    42121 agatggaaaa gctaagcaag aggaggtatt ttaattatgg ctaaaaaagc accagcaata
    42181 atgatgtgtg aaaatatgtt ctgtggaggc tgtggacact ctatagtcga tagaattatt
    42241 ggagaagtat taacagaaat ggatatatgt caagatacaa ttatatgttc agatataggt
    42301 tgtaatcata tgtttcaatt tagtatgaat gtagatgttg tcgttccacc tcatggtaaa
    42361 atgggagcag caatggcagc tatgaaaaga gttagaccag ataaatatat atttacaata
    42421 gctggagatg gtggagctta tgcaataggg cttggagaaa ctatgtcagc tgctactaga
    42481 aatgataatg taatatttct tgttatgaac aataatatgt ttgcaatgac aggagggcaa
    42541 atggctccaa ctactataga aggtcaatat acagcttcta ctccagcggg tagaaattac
    42601 gcagatcatg gttcaacatt tgatgttgta aaagttatgg gaaatttaga tatagcatat
    42661 ctagcaagag gaacaataac taaccctaaa gaaataaata caacaaaaag atacatcaaa
    42721 aaagctctag aaaaacaaaa agaaaagaaa ggtttttgct taatagaagt gcttgtacca
    42781 tgtccaacaa actggggatt aaagccagta gatgctatga agagaattga aaatgaactt
    42841 gttccaaagt atccacttgg agaatttatt gattagggag gaaataatat gttgaatgaa
    42901 attatatgtg ctggttttgg aggacaggga gttcttacag caggaaaaat tataatgtat
    42961 gttgcatata aggcagaaaa gaaaattaca tggttcccat cttatggaaa tgagatgagg
    43021 ggaggaagtg caaattgcaa tgttgttgta agtgatgaaa aaattgcaaa tccttgtgta
    43081 aaaaatccag atatactatt gggaatgaac agcgtatcag tagataagta tgaaagttta
    43141 atgaaaaaaa atggttatat gtttgtcaat gaatcactag taagtaagga tagaaagtac
    43201 agagaagaca ttaatgttat aaaagtacct gttactgaaa tagcacaaaa tttaggcaat
    43261 gaaaaagctg ctaacatttg catgttaggt gctatggtaa agagtttgga tttatttaca
    43321 aaagaagaat ttgaaagtgg tatgtgtgaa tactttgaaa atcaaggcaa aggtaaattc
    43381 aattctaaaa atgtagaagc atttgaagct ggatacgact acgaatgaat attttaaata
    43441 tttaaaataa ttattgaaat acttattttt atatgttagt atttaattaa taaaatatag
    43501 aacgtcgttc tggacaatag gacgaagtct ttaggtcgga atacaagaac ggcgttctgt
    43561 atagtagaac tagggggtgt taaattgaaa gttttagtaa taaatcctgg tggtacatcc
    43621 acaaaaattt ctgttttcca agatgaaaat gaaattttga aaaaaaatat aacccataca
    43681 agagaagatt taaaaaattt ttctaaagta tttgatgaat atgattatag aaaacaactg
    43741 atagtagata ttttaagtag tgagaatcat agtataaatt cttttgacgc agtagttggt
    43801 cgtggtggac ttatgaaggc tataaaaggt ggtacctata ctgtgagtga agaaatgatt
    43861 gaggatatga gaaatgaaat aaatggggaa catgcatcaa atttaggtgc attattagct
    43921 aaaactatag ctgatgaaat aggagtacaa tcatttgtag tagacccagt ttctgtagat
    43981 gaatttgatg atgtatcgag gattacagga atatcagaca tagaaaaagc aagttggtta
    44041 catgcattaa accataaagc tgtttcaaga aaaattgcac aaaaactagg gggaaaatac
    44101 gaggattata actttattgt agctcattta ggttcaggaa tatcgattgt agcacataaa
    44161 caaggcaaaa tgattgatgg aagtggtggt aggtctgatg gtccattttc tccagaaagg
    44221 agtggtggat tacttgcata tcctcttata gaattgtgtt actccggaaa atatactcat
    44281 gatgaaatgg tcgcaaaagt aagttcgatt gggggaatgt acgattattt aggaacaaag
    44341 gacatgatag aaattgaaaa cagaatcaag gagggtgatg aaaaggcaaa acttataatg
    44401 gatgcattta tttatcaagt agcaaaagaa atttctatgt atggagcttc actttcaggg
    44461 aatgtagata gagttatctt gacaggaggg atatctcact cagaaatggt agtcaaagga
    44521 gtagcagaaa aagtttcata tctagctcca atagagatag taccaggaga gatggaaatg
    44581 gaggcacttg ctctaggggc acttagagta cttaatggag aagaaatagc aaaaacttat
    44641 taatatttag gagaaagagt atgttaaaag attttaataa tttattagaa gaggctaaaa
    44701 agcttgaacc tgttattgta agtgttgctg ttgcagaaga caaagaagta ttaaaggctg
    44761 tgaaatcagc aacagattta aacattataa agccaattct tgtaggagac aaggataaaa
    44821 tagaaagtat atcaagagaa attggattaa aaggtcatga aataataggt tgtcaaaatc
    44881 ccgatgaatc agttaaaaaa gctgtagaga tagttaaaaa taaggaagct aaagttctta
    44941 tgaagggatt agtaaataca agtgtctata tgagagctat attaaataaa gaaacgggtc
    45001 ttagaacagg aagattatta agtttgcttg cagtatatga attacctcaa tatcataaac
    45061 ttctttattg tactgatagt ggaataaatg tatcgccaaa cttaaatcaa aaaaaagata
    45121 taatgacaaa tgtacttctt actatgaaaa gtataggcat ggaaaatcct aaaactgcga
    45181 tacttactgc aaatgaaatg gtagacccta agatacaatc tacagtggat gccaacctac
    45241 ttgtagagat ggaaaaatcg ggagaaatac caaagtgtat agtggaaggt ccaatagcat
    45301 ttgatgtagc atttgatgca catgcagcag aacataaagg tattaaaagt aatattgctg
    45361 gtgatgttga tttattagta tttccaaata tagaagcagg gaatatatta ggaaagtcat
    45421 ggcttagatt taataaagct aagtgggcag gtatagtttt aggagcaaca aatccgataa
    45481 ttttaggttc acgttctgac acagctgaaa taaaaataaa ttcaatagca ttagcgtgcc
    45541 tagcatcaca ataagaaatt attattaagg aggaaaaagt gttatgaaat atgcaaaaag
    45601 aatggatatg gtaaaagctt cagctataag agattctcaa aagaaaatag ctcagaaggt
    45661 agcaagtggt ggaactgtta tatcttttgc tgcagggctt cctgacccaa atttatttcc
    45721 aatagaagag ataagtgaaa taactcaaaa agtacttaat gaaaggggaa aatttgccct
    45781 agcatatgga cctactaaag gtgaagatga gttgttagat ctattagtaa aaagaatgaa
    45841 agaagaagaa aatattgata caaaagcaga aaatattata ataactactg ggtcacaaca
    45901 agggatagca ttaagtgcta tgattttatt agaaaaggga gatgtagtag ttacagaaaa
    45961 tccaagttac ttaggtgcaa taaatgcatt tagaccttat gaatgtgatt ttttaggagt
    46021 agatacagat gaagaaggaa tggtaacaga tgatttagac aaattattat ctgaaaattc
    46081 taacataaag gtgatatatg taataccaac atttcaaaac cctacaggaa aaacatggtc
    46141 tttacaaaga agaaaagatt ttatggaagt cgtgaataaa tatgatgtca tagtaataga
    46201 ggataatcct tatggagaaa taagatttac accagaacct ctacctacac ttaaatctct
    46261 tgatactaaa gataaagtat tgtaccttgg gtcattttca aaggtattat gtccaggatt
    46321 tagagttgct tggatgtgtg gtaatgtaga catcatagat aaggcagaac ttttaaaaca
    46381 aggtatagat ttacagtcaa atcaattttc gcaagtacaa gtaatagaat ttttaaagaa
    46441 atacaactta aatgaacata tagaaaaaat aagagcagag tataagaaaa gatgtctgct
    46501 aatgttagat gctatgaaga aacatttccc agaggaagct aaatatacag aaccagatgg
    46561 aggaatgttt atatgggttg aacttcctga aagtataaat gtagatgatt tattagataa
    46621 agccattgat gctggagttg cttatgtttc tggagagtcc ttctttgcaa ataatggtcc
    46681 aaaaaatact atgagactta actatacaac aatgtcagaa gaacaaatcg ttaaaggtgt
    46741 tgagatactt gcagaagtta taaaaaaaga actcaattat gcttgtgaat aaatataaaa
    46801 agtgagggtt taaatatggg agaaaaagaa aacggtataa agtttggaaa gttaatgttt
    46861 caacttgtta ttatagcaat atcttgggaa ttagtttata ttataccatt tatccaatat
    46921 acattatatg atccaatcct aaaagcatta gaatgtacaa acactcaact aggttttcta
    46981 cttacaattt atgggttagg taatatattt ggagctccta taggaggctg gttagcagat
    47041 agatttgatt atagaaagat aattttaggt tctgtatttc ttaatggagt agtatcattt
    47101 ttatttgcat ttaatatgaa ctatccattt gcagttgcta cttgggtagg ttgtgcaatc
    47161 acatcattag ttatgaacta tccttctatg gtaaaaatac ttagagttat aggaaaagat
    47221 aatcaaggta aggtttatgg atttaatgaa gctatggttg gagtttctgg agtagtaatg
    47281 ggagcaatat tcttatatat ttatacatgc tttgcaactc ctacattggg tatgagatgg
    47341 gtaatgatat ctttaggaat attatcaata gcaatgtgtc cagtattatg gtttgtaatt
    47401 aaagatgtag atattaaaga agaaagagaa gaagcaggtg aaaaaatgtc tgctggtgat
    47461 tttataacag tactaaaatc accaaatact tggctagtag gaataagtat attctgtgta
    47521 tattcattca cagttacaat gtcttatttt acaccatata taacatctgt acttggaggt
    47581 tctgtagcat tatctggtac attagcaata ataagacagc atggtctaaa attatttgga
    47641 gcaccatttg gaggatattg tgcagacaaa ttaaaatctc ctacaaaagt acttttacca
    47701 atatatgtat ttggtatagc agtaatagtt ttattcctag tattacctgc atcaactcca
    47761 atgactatat tcatagcttt aacatttgta gtaggtatat taggttacat gggaaaaggt
    47821 atatattatg cagtacaaga tgaagtaaaa gttccagtta aatattcagc aactactata
    47881 ggtatagctg cagctttagg attttcacca gatgtattcc aatttgcatt aataggacac
    47941 tggatagata cttatggcaa taaaggttac acatatacat ttatattcca aatagcaatt
    48001 ctagttattg gaatactatc ttgtttatat atattaaagg ttaaaaagag aagagcaagt
    48061 aaattagaag cttaaatatt caatttggta attaagtata tataaataca atacttattt
    48121 tgatgaatgt gattgtataa ataacataaa aaatatcaat agattaagtt ttataataat
    48181 gtttagagaa taaagtataa aaatcaaaat gttatcaagt tttctaggtt ttaacataaa
    48241 gttacccctg aaggtgtaaa attgagtggc aattattatc tattttctta cctacataaa
    48301 cctatttaat ttaaattcta agagattttc aaaatagatg gtagttgtac tcaattttaa
    48361 acctcataat aaatacgaaa atttaaaatc taactagata ctatttaatt atatattaat
    48421 aaatatatat
//
LOCUS       DAMJXI010000026        47499 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.027, whole genome shotgun sequence.
ACCESSION   DAMJXI010000026 DAMJXI010000000
VERSION     DAMJXI010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 47499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47499
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.027"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(78..536)
                     /locus_tag="PC465_001879"
     CDS             complement(78..536)
                     /locus_tag="PC465_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649177.1"
                     /translation="MKKTIALLLTLCAVMIPFTAFADGNDYEGTGNSQTVELIGQPNS
                     DSPSTKSVVVPGGTANLTAMSGGQLSWRVTSTLGNILGFEGNIDVYKAGKIVSSQFVS
                     FRLAGTTKTGVVSFKGLKKGSYIAKFKGKGVCTGGIILFSSPAEASFTIR"
     gene            complement(571..873)
                     /locus_tag="PC465_001880"
     CDS             complement(571..873)
                     /locus_tag="PC465_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649178.1"
                     /translation="MEVNLHTGKDEFFKSHEVAKNYIGGLYKLIDVYKFSMESVSVLT
                     RIDLDKLNNFYAGEASLNYDELCLIESVIITPLVGAFETAEYNYNMIIKARKERKL"
     gene            complement(1266..1418)
                     /locus_tag="PC465_001881"
     CDS             complement(1266..1418)
                     /locus_tag="PC465_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649179.1"
                     /translation="MDNFLFNVLASLTASMVVYLISKLFKKAKSHSRAKSDLQVEFKF
                     IFKFKK"
     gene            complement(1538..2272)
                     /locus_tag="PC465_001882"
     CDS             complement(1538..2272)
                     /locus_tag="PC465_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDF2649180.1"
                     /translation="MYYVYKYINPDTEECLYVGKTENICDRHASHLSNKKENWCNKNL
                     RLEYMELDNKYTMDFYEIYLINKLDPKFNVTGKGEMDIAKTSFSYNGQWVIYSERDLM
                     SSLASKRCGINYEVNAKMLGIMRKLKKISNNEEIFIGNENIKIKYSFETTLEGIDLEP
                     CILSVAYKKLKESTVGTLISVKREYISENVCLIIDSIFLNEIMKDPLMSKSDIKDLNS
                     QVNDILKIIGVDCEWNKLPDYCSANS"
     gene            complement(2292..3092)
                     /locus_tag="PC465_001883"
     CDS             complement(2292..3092)
                     /locus_tag="PC465_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDF2649181.1"
                     /translation="MYYVYKYIDPTTEECLYVGKTEDIYARHSSHLSNKEEDWCTKEL
                     ILKYIELPRRYNMDFFEVYLINELNPIFNKLSKGDMDTEHIFFDYKEEDWSTYSEEDF
                     KEKTKGKRRFRERKIDMKYEVSKKSINFLKRIEKLDAKVEMLYENNVLSVLYNFENMD
                     IEFCENELDINLISYDFETLESFGSCSLISVYPRWKEYTATNKKILIDITLEIRIGSL
                     ANLMELMPTFEYKIAEIFQQIEDIFHILEVGYTWQELFEIYKGCKYDN"
     gene            complement(3112..4299)
                     /locus_tag="PC465_001884"
     CDS             complement(3112..4299)
                     /locus_tag="PC465_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HDF2649182.1"
                     /translation="MEKKEILMQPNNLIKSKYDFTNVENKLFYKILFNAQKQQNSSYV
                     TTISKEELKVFMKNNNDYEHKNIKEILNMFQQSVLEFDYIEETTGKLKTFGSGLINTY
                     ELDHTDQIYTIMMHEVLYNHITDFVKMQKKKNGYTAINLSVLFNFRGAYTQRLYTLFR
                     LWSRENKEVEIKYKLDELRFYLKLKDNVYPEYKYFKQNVLKRAMNEINKKGNMVVSIK
                     EEKRKNRKIDEIIFSVIDYEPRKYFDKDILVEDYIPKKKQDNEVSFSFYIPNENIFTT
                     GTIKLFKEDFKEFDFKKDVYLNAFNKSIAIALERDNTDIINTKNYDFFKSTLSNKISE
                     VIIHQKDDLKFKEELDKYWDDEDVKKEEREVDYSKDPVRLETVRRNLFDQGLVNEEGY
                     YYK"
     gene            complement(5021..5404)
                     /locus_tag="PC465_001885"
     CDS             complement(5021..5404)
                     /locus_tag="PC465_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2649183.1"
                     /translation="MKIKKIPESELLVMMYIWDSEDEEVASTEILKTLGEKYEWKKST
                     MLTFLRRLVGRGFLEVVKKDRFTYYKALIEKEEYLKVETKSFFSFFHKNSFESFISAL
                     HDDEEVSENKLKSLEKFIEDWEEDK"
     gene            5778..6293
                     /locus_tag="PC465_001886"
     CDS             5778..6293
                     /locus_tag="PC465_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2649184.1"
                     /translation="MSKMIQCKSCSKEIASNAKSCPNCGAKNKKPFYKRGWFIVVVVL
                     VLLYAIGTSGSGTDDTAESNDDGTSKTASVDKPEEPKKEKYEIVGDITSETDSMATYI
                     KGVIKNNSGHDISYAQVTFTLYDKDGNQLGTAMDNINDLKKDGTWKFKAMGMNTDGEI
                     ASYELSEITGF"
     gene            complement(6877..7248)
                     /locus_tag="PC465_001887"
     CDS             complement(6877..7248)
                     /locus_tag="PC465_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2649185.1"
                     /translation="MENIKEESVLKTLREALGLNQSELANILKMTPSAISKIEKNGKP
                     LSDRISSQLSKEFGVREEWLKNKEGKMFADSSDDDLVAEIAANIINSDDKFMKNVIIA
                     FNKLTEDQRNFLINFMKELDK"
     gene            7407..7583
                     /locus_tag="PC465_001888"
     CDS             7407..7583
                     /locus_tag="PC465_001888"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649186.1"
                     /translation="MKKIDTKKISKNIKESTEFGILYSSLKDKQRDRVLGIMEGMKIA
                     NELSENNFMDIKHS"
     gene            7600..7818
                     /locus_tag="PC465_001889"
     CDS             7600..7818
                     /locus_tag="PC465_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649187.1"
                     /translation="MNDEMITKMFNLNETYKMTSIRLNLEVKGVITHIDKNEIVLEYY
                     DNELECITTKILTIDDIKYNDYNLKPLH"
     gene            7848..8474
                     /locus_tag="PC465_001890"
                     /pseudo
     CDS             7848..8474
                     /locus_tag="PC465_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425622.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(8537..8911)
                     /locus_tag="PC465_001891"
     CDS             complement(8537..8911)
                     /locus_tag="PC465_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2649188.1"
                     /translation="MEKQNLEDNERRQRLKDIRLSKKLKQKDFGKKLGLSLSQISSYE
                     TGHRKIPQRTINDICREFNVNEQWLLHGEGEMFVDITEDLETSEEIKTMIKKIFALED
                     EDREAIEKIIDNAYLKIKNEEL"
     gene            9065..9241
                     /locus_tag="PC465_001892"
     CDS             9065..9241
                     /locus_tag="PC465_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649189.1"
                     /translation="MNQEKEKANDLLLKLELLKKINPQEFGYISGRIDVNIEKLKQET
                     ERNKSKKIRYRKGA"
     gene            9245..9451
                     /locus_tag="PC465_001893"
     CDS             9245..9451
                     /locus_tag="PC465_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649190.1"
                     /translation="MTFNKNQIGAAVQLQDIRFDTKVDCIITKVEKNEILVMYYEKET
                     EEIAYKTLTKEDLILDDYKLKLLY"
     gene            9480..10202
                     /locus_tag="PC465_001894"
     CDS             9480..10202
                     /locus_tag="PC465_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2649191.1"
                     /translation="MDFLKDARKKEWFWLENDLVDREDLSVYEKMAYMVMARYSDDES
                     SCFPSLSLISKKMGCGITTVKKTINSLEEKNLIIKVHRKVKNKKENDTNVYYIMSLKG
                     KSSGDIGHEATDGRSPYDQQVGREATSKKTYNKKTYIKSNTTPQNEPKTDYLDLSFLD
                     LDIEKVKLTKDEYDKLISKFGKKYIHDKIVSLENYIVNGKGSRYKSHYRALLTWGNGD
                     VSKGIVSEVTKAKNTLSGFKEL"
     gene            10231..10449
                     /locus_tag="PC465_001895"
     CDS             10231..10449
                     /locus_tag="PC465_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649192.1"
                     /translation="MEDEKLELTEKDLHCIARHLQNEVMEMVFRGNIEAPTSCEVCDY
                     LQECKDYFTHIDTFIKLSEMTGVDIFTK"
     gene            complement(10468..10680)
                     /locus_tag="PC465_001896"
     CDS             complement(10468..10680)
                     /locus_tag="PC465_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649193.1"
                     /translation="MNMCKIKTLREKCSLIDDKVEFSGEYKTFPGFAGSKLLECECNK
                     NYICKIQIMTANSNCPLFKKARQLQY"
     gene            10843..11103
                     /locus_tag="PC465_001897"
     CDS             10843..11103
                     /locus_tag="PC465_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649194.1"
                     /translation="MKEEKLELTEKELHCIARHLQNEVMEMVFRGNREAPTSCEVCDY
                     LQECEGDFTCMYHSFTKLSKITGVKVTAFKYCFPDENPKATI"
     gene            complement(11096..11284)
                     /locus_tag="PC465_001898"
     CDS             complement(11096..11284)
                     /locus_tag="PC465_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649195.1"
                     /translation="MSQYRVISKECPVINETISLTCEYSAPPGTFGSKLMSTRCDGSH
                     ICDSSSNEECPILKKLLR"
     gene            11422..11739
                     /locus_tag="PC465_001899"
     CDS             11422..11739
                     /locus_tag="PC465_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649196.1"
                     /translation="MERKKHELTDQDIQRLIEGLRTDPKIREMIFESKGCETRTSTRS
                     KCEQFVEEKLAYRSYGFETPKYYAKLIADIIDILVYKNVPRDRICGVLYDVERVIPLV
                     VTF"
     gene            11761..13092
                     /locus_tag="PC465_001900"
     CDS             11761..13092
                     /locus_tag="PC465_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2649197.1"
                     /translation="MNYSLEAEQNILGSFLINDSIGYKIRELKENDFYFESHKIILSC
                     MKRIIDSNKPLDLLLLKNELEKIDRLVDVGGVSYITSLTTIVITTSNIDHYIKIIKEK
                     LLKRQISELANELINNSNSDTSIDELIVDINDLKALVTTSSGINDNYIDASKIKREKG
                     VHKSIDTGFNKLNNMLDGFRYGTLTILTGKPASGKSTIVNQFIAQAITNGEKAFLYSG
                     ELPSFMAMDWFRKTVANDYHIKEYKSVYGGTYTDIPDYASELISDWIKDKFFLYDEDA
                     ISDEVNLLNTIEHLYLKKGVRFFVLDNLMTIKTGNKADKYERQEQIVSNLKNLAKKYN
                     LVIVLVAHPRKNMGDMKPTMYDVSGASEIVNYADYILSTYRVIDEEEETDDTYLLILK
                     NRITGKQNISFKMNFSERRKRLYTTSEELNRDYKYDVNKQYVQVEIPEDVF"
     gene            13465..13851
                     /locus_tag="PC465_001901"
     CDS             13465..13851
                     /locus_tag="PC465_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649198.1"
                     /translation="MIALEKFAGGVLKEKFNTELQKVLDNIADPNTDFKKTRKISLEI
                     VFKANEDRDLAEVDIKSKSTIVEAKATTTKVLIGKDLETGRVEASEFKNQVAGQLVMD
                     IPDSEETNETEENSASVIDFRNASSK"
     gene            13903..14607
                     /locus_tag="PC465_001902"
     CDS             13903..14607
                     /locus_tag="PC465_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649199.1"
                     /translation="MIRNAMEYLVKLGKRETVCVDGFKYTTDALEIIKEPKANELEIT
                     TLSGLVDYIRSGIDHKADELLLIQVLTPRKVLLKSPLRKNRDRETYIECVALLPEKRF
                     DRPLDLDSFNIMLQSAFIKNNDRDTLLKIAGNIQESTVKNVGDDGVSQSVTIKTGVAS
                     VSEAIVPNRVKLIPYRTFQEIEQPESEFIFRMSSGPAAGLYEADGGAWKNQAMLNIKA
                     YLQEELKDFKNVNIIA"
     gene            14664..14846
                     /locus_tag="PC465_001903"
     CDS             14664..14846
                     /locus_tag="PC465_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649200.1"
                     /translation="MKMISHMNILERAEFTDKIANAIMSANKEIERGCAFNEAVEIVK
                     QMEYRENKYNEGDIAI"
     gene            14843..15220
                     /gene="ssb"
                     /locus_tag="PC465_001904"
     CDS             14843..15220
                     /gene="ssb"
                     /locus_tag="PC465_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2649201.1"
                     /translation="MNNVVLVGRLARDPELRYIPEYGTPVATFALAVDRGYAKKDGTR
                     EVDFIPIEVMGGSAEFCANYLAKGRMVSIQGQIRIEKYEKDGEKKTFTKVRTKIVNAL
                     DHKPKDEEKEIGFQVLDDEDIPF"
     gene            15198..15782
                     /locus_tag="PC465_001905"
     CDS             15198..15782
                     /locus_tag="PC465_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2649202.1"
                     /translation="MMKIFHFKLDGDYMRSLEEKNKLFEDNINLVHFIINRYFKSFLR
                     RYPYLKEDLFQEGYIGLYKTTCCFDESKGKFSTIAFLYISGHLKRFTTGYVKKHYRND
                     IDSFEKCIYRDNYGEEIRIEDRLAGNENVDIENVRVIRSCIKRSEIKDIQKIVCLREK
                     GYTQQEISKVLGTSQASIYRRLKKLKTEINILGK"
     gene            15811..15969
                     /locus_tag="PC465_001906"
     CDS             15811..15969
                     /locus_tag="PC465_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649203.1"
                     /translation="MKTKIIGGRENECPICNGNIFKIETLIGIVWQCKDCGCMYQDMS
                     SKESKRGY"
     gene            15972..16298
                     /locus_tag="PC465_001907"
     CDS             15972..16298
                     /locus_tag="PC465_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649204.1"
                     /translation="MSCVIKCDFCGETIAEILNIKVFRIDDEGNIMSIGKDVCDKCYD
                     RLFGSNLNKKMTNYEKIKNMSKIEMAEFLANGGSGCTSCAYDFQECLGGCLEGRKKWL
                     ESEAMK"
     gene            16298..16834
                     /locus_tag="PC465_001908"
     CDS             16298..16834
                     /locus_tag="PC465_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HDF2649205.1"
                     /translation="MKKTLIIVGVVISILIMLACLFLVTKNKAIDLEEQVQSATASVE
                     VQEKRRIDLIKNIVDCVKDYAKYENRTLKEVTDMRVSANDESIKEAKLNIQAVAEKYP
                     DLEANENYKQLMSELSITENMIAQHRENYNMQVRNYNKYIRKFPANLILNSMGYEKIE
                     SKYTEYKAKEDAPQNLFD"
     gene            16846..17652
                     /locus_tag="PC465_001909"
     CDS             16846..17652
                     /locus_tag="PC465_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649206.1"
                     /translation="MKFKTFEITKREFLVSIIIACMMIVLGFFIDDKVQSKFLEDNER
                     YYKATKINNDKDLFDYAMETSAGDSLISGRFKSVDSVSIEELKGDYWFIERTEEKYTM
                     HTRVVTTKDSEGHSHKYTETYWTWDYHDSIEKKCNKFNFMGKEFDAKVITNLSKERLA
                     LKKDIFKNNNLKIKGNYAYINNKRRYYYEVIPKEFNGTMYANLKNNTIANPADKNIKV
                     FKGESIQNVLENNNFNIGFFKVVFWIIWILITTIIIYVFYYLKNDWLEDK"
     gene            17677..17937
                     /locus_tag="PC465_001910"
     CDS             17677..17937
                     /locus_tag="PC465_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649207.1"
                     /translation="MKCKVYHAIKNMKDANELIDRFETENIFFELNDIDNENVLNGEM
                     DLTDIEDIASLQFILDGDLFIFNSCDEMIFMNKYTQKELGLQ"
     gene            17938..18579
                     /locus_tag="PC465_001911"
     CDS             17938..18579
                     /locus_tag="PC465_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDF2649208.1"
                     /translation="MNKRIVCQDTNEIVYNYKEYQKTKHWESLKNEFYFSNECKCVLC
                     DSVKKVSLHHKTYRRIGAEELDDLIPLCNSCHYKVHRNNKQYLFNDATEKQIRYINDL
                     LEVYVDIVEELFMNEYIYLYVAMGIGFYNKNLMLFEANHIINDLKFVSAMLYEFYATK
                     LEIKLPGYFNGFDYEEIKDSLYKKMQRLSKYIYVPKKQEIELLFKKRKKEHYE"
     gene            18634..19119
                     /locus_tag="PC465_001912"
     CDS             18634..19119
                     /locus_tag="PC465_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649209.1"
                     /translation="MDLKLISSIPNWKVEDQLAKIDEEVTEFKEAIDTGITKDIIAEG
                     LDVCQTILTMFQVLEIENYITEGVETHNKKLNGRGWDLKEIGDDILNLIKNSMINELI
                     NMNKKLKCLDEKEFNAKIQFLDVDKLWNLCMPLVNLSTIKGVNESIDEMKMGEFLKNI
                     N"
     gene            19139..19396
                     /locus_tag="PC465_001913"
     CDS             19139..19396
                     /locus_tag="PC465_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649210.1"
                     /translation="MLIEVTENNRELKVGDIVEINGGNKLYMILSLKETIGGYVIINM
                     QNGYGSFGVYKSLSQLELDLKVRGYKLYSSDDYKLQLVPRE"
     gene            19506..19949
                     /locus_tag="PC465_001914"
     CDS             19506..19949
                     /locus_tag="PC465_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase subunit sigma"
                     /protein_id="HDF2649211.1"
                     /translation="MQSSKKDNLFSSAEGKLYNYKKIKAEIEKIDIDMQMIKNDYRGC
                     SGVEIKEKTGKTYDIKSVIEIETEEKEKKIALKEKEKRHKELIIEKIDNAMKILSEEE
                     KKIVQYKYFSSSRTSWEYVGRMIGFSASKCKQMRFDIIDKIKGLL"
     gene            20092..20637
                     /locus_tag="PC465_001915"
     CDS             20092..20637
                     /locus_tag="PC465_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649212.1"
                     /translation="MAWNLRSKSFLLSREVLKIKRDITEEISSAVYVPDNLKYYDNVM
                     KETPGMYGRECSLDFIKKKQEKLLKLKKKVKKNYDSNINKIDSYLKILEKSIIDESDH
                     VELVVFKLYLQLENVVKVTETVNDLGFRIKTNTYARERKYSTNDITSIITDPFTDVVE
                     DLKILVQERQRKNYYGNKECF"
     gene            20641..21285
                     /locus_tag="PC465_001916"
     CDS             20641..21285
                     /locus_tag="PC465_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2649213.1"
                     /translation="MEAHSGQKVNPIKDIEDVFRLLNFLEEWNERNYLLALFGMCTGL
                     RVGDILALKVADVTDLKLDKKGNKIRVSKDWIRVIEEKRDYNREVFLSDVIKSAIENY
                     TQDKPGEEFLFKSGKRKKFNRPIQTRQAGRIIKGAAKKVGIKENVATHSLRKTFARHI
                     YDEEENKTYALELIRKILGHKTIEMTRRYIGIDKDEEVKAITKFTNKLKKRKRN"
     gene            21500..21958
                     /locus_tag="PC465_001917"
     CDS             21500..21958
                     /locus_tag="PC465_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2649214.1"
                     /translation="MDVNEVEIIDSSYEKGKELTEDQCNMVTLLITGATVTETARIIG
                     VNRKTIYNWMNKEHVRKEMDRRKQELTNQGNLMILKDLDSYINNIKELASDKSDKRVM
                     LAANQYLINRIYGTPTSTVIQAEDNSVGMGMDATEIEAAIAKIRIRTSKK"
     gene            22523..24262
                     /locus_tag="PC465_001918"
     CDS             22523..24262
                     /locus_tag="PC465_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003495386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649215.1"
                     /translation="MDNLERNIQLIFSYLAKTFIRNGATIKDAEKEANEIIKANSSNI
                     WGVNGLAYQLGKINLEFFCMYFMQDTYLPKEDNAAAPIAKVHHELWEDIQESIIGDGP
                     QQLGRIYPRGTGKSAFGDLATTVWSHCYKHKTYTLICSDIGSTAEKFVKDIKNALLEN
                     EYIKKAFGVLLNDNDRKYICNSTQLELTNKTFIEAISSSSPMRGRKYNNNRPDLIILD
                     DYQSEENVRTEDAREKKFKRFSDDVKYAAQKPVIRNGKTIKRGTTFIALGTLQHKECF
                     YSRLKNLPTWKFKCEKGVLVDNVDELFNSGLWLNFKELLFDFKNTNHLEDAKEFYWEN
                     EKEMKFPILWPSFWDCLDMALSYYENPTSFKQEVQNDVNSIGEKWFKTIRTESREYIE
                     THTFKKTMLLCDPASAGGSKHDYSAFLVGSESENSLLYGRLAELAKINARTDFDKYID
                     HMIYLLKVYPDITHVYIEKNTFNGADANQLELKIKNDDVLYYRDIEIINEHQKKNKDD
                     KISTLIPVLSKGQMVFAEEDKEFIQQILDFTGQKYSLHDDAPDISAEFINRIFKIEVI
                     EKVSFLDRRKLGV"
     gene            24266..25588
                     /locus_tag="PC465_001919"
     CDS             24266..25588
                     /locus_tag="PC465_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015616244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF2649216.1"
                     /translation="MKLNELIKNIFNKNDTLDLNKTDHLDLVKKIYGQHYSKKYVYEK
                     MYRYYKGDTDAMRKYKFVTERSNLKTNVNYIKKFIKEEVSYTVGNPITYESRSGNINF
                     VNDIEYYTTHWDELHDSDLMKYLLIFTKVYEIYYINKEMEFCSEIIKPTDGYAYKNKN
                     GKILFFIHSFKDPFDCTINYIDVYTSNKIYHFDDSFNQISEPSTHIFKEVPVTIGKLT
                     LENENDSLYKDLKGLQDGFETNFSDIGNEISDFRNAYLTFIGCKVDEDDLPKMKEKGI
                     MQSSDGKIEWLIKNINDTFVQNTLDRYVDTMYQISCHINHNEGLVSNLSGVALRSRLI
                     ALENKCKLEELSHKNIVKNRIRFLCKYLNTIKNKDYDYKDIKAMYTPNIPMDDLGTAQ
                     MLSQAPEGTISKDTARSLFSFIHNTSNEADKVKKEFEEEYGVSENEGN"
     gene            25575..26429
                     /locus_tag="PC465_001920"
     CDS             25575..26429
                     /locus_tag="PC465_001920"
                     /inference="COORDINATES: protein motif:HMM:TIGR01641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HDF2649217.1"
                     /translation="MKATRRQEKVVNLILKFSSKLYDDGEKEIEKLVKKYNADKEKLL
                     NEIAMILLKYKVINSMMDLKRIERISLYKTLVHQIDEFTQMNKKTEKDVLTSLLLSTA
                     YHKFNTNNYVFILGSKLNLKNITDKEIKKILDVRIDGKLYSDRIYKNKNEVSAKLKKD
                     IDNLLKGKTSINDIEKSISKRFGTLEEDTKRLIENEISRVQSQVNELWMQKNNIQYVI
                     YSSALDHKVCEYCSQYEGQVFFINERPVELPQHVRCRCIYIPITNTWEYTNEITNITW
                     DSYLNSIE"
     gene            26465..27106
                     /locus_tag="PC465_001921"
     CDS             26465..27106
                     /locus_tag="PC465_001921"
                     /inference="COORDINATES: protein motif:HMM:NF025623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HDF2649218.1"
                     /translation="MLKKDLLNLIKNASEEQDIDDLLKNSDLAKKFTTEGLTLDNFKE
                     LCSKDEIFKSFLENEKNNDFENKLSEWKKENLEKELSPFIKEKYPELIEDPVQKQLLE
                     QQKEIERMKAENAKKDLLNLSIKYISENKKAVPGDWVEKFLGEDFETTKTKLDEVSKM
                     IEDRASLMFESKIKDTTYIPGMGNNGEISSIGQMLADNANKNSKLESDPWANE"
     gene            27123..27503
                     /locus_tag="PC465_001922"
     CDS             27123..27503
                     /locus_tag="PC465_001922"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649219.1"
                     /translation="MFFIKKPYINDLEVLANSANLVTISSTINSENVNLNSEGKKYVV
                     SGSLIDLDGNIVTEIKSGSEGSFTYSLSSTPIGILYKTVNVTNGNMSGALIIEGYVRE
                     DRVLENFENTKDEIKNALPEIKFM"
     gene            27513..28535
                     /locus_tag="PC465_001923"
     CDS             27513..28535
                     /locus_tag="PC465_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002599761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HDF2649220.1"
                     /translation="MARIDEVFNTKELINYFKKREFPELLGAKLFPERKIQDIRFDMI
                     LGKSGLPVSAEIHAMDTETTIASREAIDKGAAELALVKRKIALRGEDLIKIQSPRNDA
                     EFKLALQEIYNDAEKMYKAVLVKAEAMRMEVLATGKLKIEENNIKVTLNYGIPNSNVK
                     KFNWKDVNVKPLEDIEVLVDTVEDASGNRPSKMLTSRKILRSICSKESVKKAVFGTNS
                     DRIVTQAQLNDLLSQMNLPTIVTNEEKYRVETAKGYETRRYYPDNALTVFGDGLLGET
                     IYGLTPEEIKLIGDGKMDVAQMIDNIFVGSYSTIDPVATYTKAAATVLPSMPQAEEIG
                     IATVEL"
     gene            28544..28912
                     /locus_tag="PC465_001924"
     CDS             28544..28912
                     /locus_tag="PC465_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HDF2649221.1"
                     /translation="MFENIKIILNIQDEKYDKIINLYIEKITNMILNYCNRKKLNEAL
                     EGFVEEKVITILTSRFDDLKKSSGLENEKSIKAITRGDTKIEYNSSVTYDISTSISSS
                     SFLSDVDKKFLSSFCVVSMY"
     gene            28924..29271
                     /locus_tag="PC465_001925"
     CDS             28924..29271
                     /locus_tag="PC465_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649222.1"
                     /translation="MTEADILEMTYLDKMTIIRKSKGWNQETCSNDFSNIIIAEDIPC
                     AISRKEEAIVNGDIGAIVINRKLFCRPEVDIKTGDTINATYSHGEEAIFKVSRANIYP
                     SHMEIPITEAERI"
     gene            29271..29627
                     /locus_tag="PC465_001926"
     CDS             29271..29627
                     /locus_tag="PC465_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HDF2649223.1"
                     /translation="MGIDNLGVFEALALDLKLNASNFNRKIKKFTNKTGQELAENIRE
                     ETLVRTEKLKNGWEESQPEYDTYIVEDKVEYATLVNDGHATKNGGIVPGSFMVEKGIE
                     KTKENMTSAKANLFDW"
     gene            29636..30085
                     /locus_tag="PC465_001927"
     CDS             29636..30085
                     /locus_tag="PC465_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649224.1"
                     /translation="MLTNRDIIIAVNEMLKNEFMDIDIFINEDNIQGFEEACFFVQLL
                     PVSNNIANKILDTKKIFIDIEYYQKARKNKLNLYDIQNRLEKIFNRNIRVKDRSLTIE
                     NISPSITKDSVGHKLTFLMTVSYFEEVYFSKETYEIMENVDLKIGSD"
     gene            30086..31141
                     /locus_tag="PC465_001928"
     CDS             30086..31141
                     /locus_tag="PC465_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HDF2649225.1"
                     /translation="MGLPEINISFIQAGKTFVKRSGGIVALILKDTKNIGLVEIKEME
                     DIPENYSASNLDYIKMAMKGNVYPPNKVLVYTLDTDESIDDALDFIETCEFNYLCMPE
                     ETEQDLPKIKAWIKKMREDNKIKVKAITASNSADYEGIINFTATDIEVEGKKYTSNEF
                     LPRIAGFIAGTPSTQSVTYAEIPEVTNIPKLTRVEANARINNGELILIKESGAIVIAR
                     GVTSFTTITDSKGDIFKKIKLVDTLDQIHNDIKKIIVKNYIGKTQNTYDNKCLLIVAI
                     QLYLQELEKDGLIDPGSTIEINLDAQRTWLKENHIDVSNMEEQQIKEYNTDTIVFLKA
                     KIKLIDAMEDVYLDISM"
     gene            31157..31597
                     /locus_tag="PC465_001929"
     CDS             31157..31597
                     /locus_tag="PC465_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HDF2649226.1"
                     /translation="MKAKIDPSRIISGTFGECWIDGRQMMAVKGLEAKIELEKEEVKV
                     CGQLMVGQKLIGASGKGSVNLFKVSSLFGEYVESMLNEGKAFKFTIISKLQDPDSYGA
                     ERVALYGCMLDDLTLADWEAGKMGEIEVPFTFESFKYLDKITEK"
     gene            31613..32029
                     /locus_tag="PC465_001930"
     CDS             31613..32029
                     /locus_tag="PC465_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF2649227.1"
                     /translation="MNTVEKLLNMDAGKLKMPSSIFELYCKKLDDILEIECNAIDPER
                     FDEIRMNSMDVDSGNLENINVYELKVNTILESCPMFRNMEVVENLGLATPKDLLKKLL
                     LAGEIDNLYEEVNKVNGIDAEGDKKRQKERAKDIKN"
     gene            32056..32205
                     /locus_tag="PC465_001931"
     CDS             32056..32205
                     /locus_tag="PC465_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649228.1"
                     /translation="MYLLFKYKGIMPSVSYRILRGEKEIVSVFMDQELDERKEEIKSG
                     AGRLF"
     gene            32209..35598
                     /locus_tag="PC465_001932"
     CDS             32209..35598
                     /locus_tag="PC465_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDF2649229.1"
                     /translation="MSSSTKVLQAVIKMRDEASSTLRRVAANTRALHDSSSQASRALN
                     NVQNNLKSVGTSALKAGGLITAGVGGAFAAATKVGTEFESAMSQVKATFGNSLKPGDF
                     EALSKAARDAGKATTKTAADSANALQYMGLAGWDVQKSMHALMPVLNLSEAASMDLGL
                     ASDLVTDSMSSMCLEVDKVSKSGKVLAGAGLSEYLDKVANASTKSNTSIQQLMEAFNV
                     AGGTFSNLKVPLSEATAIMGILANRGVKGTDAGHALNSIMVNLTTGAGQAGKAMKKLG
                     VSAFDNQGKFKGMSNVLKEVANKTKGMTDEQKNYYLSAIGGKTQLKTLQKLLDGVGNE
                     YDSLKKKIDNSKGALKTMSDVMKDNTKGGLATLKSALEETGITIYYQLKPAIASVVDN
                     LTKMTVWFNNLSEPIKRVITNVMLSVGAFGVLLLTIGAVSLIVSKAIGIFGFFVPIIL
                     RAKVAFRAFVIGMKPLSAVFLAVMGPIGWTITAVIALSVAFTIAYAKSEVFRNKVNSL
                     VKSFTEFAKPIVNFCMPALKQLGEKFKELLSAFGPLFASILNLGSVIMKVLGPVLIGV
                     IGFHIAKLVLILSTLATAFKAVVDTITNVLNGLASILNGVFDLIIGIVTGDSKKMMDG
                     VKQIFDGGTKIIKSIWKGFIDFVTAPIQAIADIADSLFKDKAKWLTDKWRDLRTFLEN
                     PIEATAKISTKTNANIPGSKAADAAGKSTPNTGGLKQTVANLKGSFSDFKTFIKPMTD
                     SISQGVESGKTKFTELQNKILNDVKPALKVLEDSGVNFKDKFKESITSIKDKFNELKN
                     ILAGNIKTNIDNLVKAFEPLKPHLDNLKDCFDKVKKAITDFFTPAKQVGDTVNKVSQP
                     MDSVKKSTDGIKLSFQSLIQALAPVKAWFQGFMPFLSQIGQQLLPSIGIAIAGVVGGI
                     ILAFTWVLNTLTAIITTVSGIINGIMSFISGIINVIMGLITGNADQTMDGLKQIFDSG
                     VGVIKSIWNGLVDLVSGVLEPVIDLADSLFKDKVKGVKEAWNKLKEFFHNPIKGMIEI
                     VKSGPSLQIGKGADAAGKSPRKAFGINRVPRNDYLIRAHEGEKLLTKQEANQYKRNSS
                     NGSLFLDKLADTIIVREEADIDKIVRKINKKISLAKVGGVL"
     gene            35645..36121
                     /locus_tag="PC465_001933"
     CDS             35645..36121
                     /locus_tag="PC465_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HDF2649230.1"
                     /translation="MNKKIPALAILIVLSLSLVGCSTNDSKNGDSKPKQNTEEIKNHK
                     IGEVVDLDGAKVSVKNVRKLESDSNVYAVEIEITNTGDTDLESDFLQNYILKTDDNTV
                     GNAINNQELNGELLFDTIHPGDTLKGEIAFELTKDTKPKTIEIAYENVGKYTVFDL"
     gene            36179..36814
                     /locus_tag="PC465_001934"
     CDS             36179..36814
                     /locus_tag="PC465_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDF2649231.1"
                     /translation="MEIWLRQANNTFRFPVIPPSFEINGSATINTSNILSVGDIAVFG
                     GLGLKTIELSSFFPNQEYSFCNYNGFPKPYDCVNLIESWMKEGYILRFIITETNINFE
                     CIIADFNYREQDYSRDVYFTLSLKEYRRIQISKVNINNDEKLSSEKDVQLTKGFDTKQ
                     KTHKVVEGDTLFKIAKKYYGNGDLWEKIYKANEDEIKDPSVIKNGWVLIIP"
     gene            37054..38571
                     /locus_tag="PC465_001935"
     CDS             37054..38571
                     /locus_tag="PC465_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2649232.1"
                     /translation="MIIDRSKDSNNNNIDFTAKDMGFLLLQSEVSYNFKDKLVEDIAK
                     QVFLENKLPLGNLPKTGVKYTKMFIGVTGYDTIMSVYTEASKTTKKKYMIESNLDKFN
                     VIEKGVVTLNITFEEGFNLINTNFSESMENVKNKVLVVDQYGNKISEKINDSIFKDVG
                     VIMQKVIQQQENSTIDIDGEFKGIEKTCSLKGYGDITCVTGRGVKVKDSYTKLIGLFY
                     IDTDKHTWQNGDYQIELELNFENIMDEKSAGQDEQKEDGSEYTGGTEYSAEFTAYCPR
                     KSEGGDKDCRGKKLDPSKKTCAAPMVGSYEKSYYTKDFLNKHPLMRYGDEIQLVTGVS
                     SRDGTYKVNDNGPAIIIEKDGTYHIDILFGNVEEANNFGRRKGKIIIGGYSGNMTEKA
                     KTVISEARKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVNLPRTSSQQSKVGKKVEK
                     NNLQAGDLVFFHNPVSHVGLYVGNGEFLHAPQTGDVVKISKLSNRKDFNTARRVL"
     gene            38585..38917
                     /locus_tag="PC465_001936"
     CDS             38585..38917
                     /locus_tag="PC465_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HDF2649233.1"
                     /translation="MADPINEFIGIMRQEGKFHNEPSFFIGKIKSKLPDLKIEINNII
                     LEKEDILIDSWMLDRQIELFDTETSQEHKHEIKNPFIDTFESGDTVIMFKIGEKFAVV
                     SKLVSLDE"
     gene            38910..39347
                     /locus_tag="PC465_001937"
     CDS             38910..39347
                     /locus_tag="PC465_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HDF2649234.1"
                     /translation="MNNNTIFPFMGAPEDYISPDNEELPIFKEFAWNFDKDEKIIENG
                     DFKIVERNEAIKVWIYKTIKTDKYVHLIYDWDYGTDIKNLIGQKYTKGLTESEAKRYI
                     QEALLTNPYILEVNVVNTEFKDDNLSISLNVKTIYGEEEITFV"
     gene            39340..40392
                     /locus_tag="PC465_001938"
     CDS             39340..40392
                     /locus_tag="PC465_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HDF2649235.1"
                     /translation="MYSGQSFSTLNNRTLNNINLPLYKGQGSSLYNIVSPINSELAQL
                     YIELSYIHKRVFIQDNFDDFLDRRVNEFGVYRKLGTEAIGEVTFEGKIGTQIPNGTII
                     SHSDLLFVIIKDITIDEDSKLNVSPIQALKIGIKYNLSANTEFKLIEEINGVTKIYNE
                     LNLKGGTEIETDEELKERFYKIQKNQATSGNKAHYQSWALEVEGVYNAKVIPRWDGPG
                     TIKILIYGQNNQSVDNEVLQRCTEHIEEEKPIGPTVTIVTPSTFDINISATLTLENGY
                     DIESIKVVFLDIINSYLIENSREIIYIKVMSLLASIEGVHDIKNLLVNDDVKNIIVDE
                     EKVPAVSSVAFDVEVS"
     gene            40394..41002
                     /locus_tag="PC465_001939"
     CDS             40394..41002
                     /locus_tag="PC465_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HDF2649236.1"
                     /translation="MKLIDYLPSFANNKIDIQIQEALENELLTLIDEKDDLLDQFFID
                     TATWGLDDWESLLGIKINYKLDFDTRRSNIRAKLRGKGTTTIEVIKAISEAYTKTNVD
                     VEVFSNLFSFTLSFITNNCSYNTILELDKKIEEIKPAHLEHKFERILFNKNGLYTGAT
                     ISTGETVTVYPYVPRDLESFGEIAICSGNDRTLEKVTLYPKK"
     gene            41019..41798
                     /locus_tag="PC465_001940"
     CDS             41019..41798
                     /locus_tag="PC465_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDF2649237.1"
                     /translation="MAEQQYFTLVTEIGKAAIANASITGEKVDFAKMKVGDGGGSSYT
                     PTESQTALKNVVWESTLEHAQADKDNPNWVVIQKFIPGDVGGFEVREVGLFDSKDQLL
                     AISSYPTTYKPTADSGTVKELLIKVILVVSNVANINLKVDPTVILATLKDIQDLDAKI
                     DTTKTELTSNIETAKTELNGKIGDTTQLTTTDKTNIVSALNEVKASVDSIETTAEKTS
                     YNNATSNLTATNVQGAIDEVVRKIEKFNEVNISIQNDMLPI"
     gene            41816..43120
                     /locus_tag="PC465_001941"
                     /pseudo
     CDS             41816..43120
                     /locus_tag="PC465_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901484.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            43483..43830
                     /locus_tag="PC465_001942"
     CDS             43483..43830
                     /locus_tag="PC465_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649238.1"
                     /translation="MDRGNRVIYNQDGKILLQTGETTGDVLEHDTITELHYLDVEYGS
                     IDYSKQYIESINPVTKELNIKNIEIVLTDEQKRLQALEKELSMLKEENKNRDSEIVNT
                     AFEVENMKLNNNI"
     gene            43842..44012
                     /locus_tag="PC465_001943"
     CDS             43842..44012
                     /locus_tag="PC465_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649239.1"
                     /translation="MYNLLKLMIEQKNYSTKEDLQHKMDVFYAVNRITEEQYLELTGL
                     LNKEETPVEPTV"
     gene            44080..44511
                     /locus_tag="PC465_001944"
     CDS             44080..44511
                     /locus_tag="PC465_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDF2649240.1"
                     /translation="MNVTIVFLATNIFIKLVILAIAFDTLLGCLRAIKTHQFNSSFGI
                     NGGIRKVAMIACVFFLAVVDILTKFNFLFMLPQDWVDFLRLNHLGISEFFSILFILYE
                     SVSILKNMYLCGLPVPKRLKEKIGSLLDTMTDELNVKGGSK"
     gene            44511..45350
                     /locus_tag="PC465_001945"
     CDS             44511..45350
                     /locus_tag="PC465_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2649241.1"
                     /translation="MKICITVGHSILKSGACTSANGVVNEYQYNKSLAPVLADTFRKE
                     GHKADVIICPEKQFKTKAEEKIYKIPRVNSGGYDLLIELHLNSSGVGAFGTEVFYYSE
                     KGKEYAQRVVDKLSKPFIRKKGDKEVGNRGVKLDKSLYILNSSKPTAILIESFFCDNK
                     EDYEKAKKLGHEGIAKLIVEGVLNKNINNEGVKQMHKHTIVYDGEVDKIPATVVGWGY
                     NDGKILICDIKDYVPGQTQNLYVVGGGACEKISSMTKENYIMIKGNDRFETLYKALDF
                     IDR"
     gene            complement(45393..45605)
                     /locus_tag="PC465_001946"
     CDS             complement(45393..45605)
                     /locus_tag="PC465_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649242.1"
                     /translation="MTWKNEIKSILVKENISMNELNNLMNEHNNKNNTVENLRQKINN
                     ETMKYSEILTIANLIGYEVVWKKKEK"
     gene            45848..46024
                     /locus_tag="PC465_001947"
                     /pseudo
     CDS             45848..46024
                     /locus_tag="PC465_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428602.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
     gene            complement(46275..47180)
                     /locus_tag="PC465_001948"
     CDS             complement(46275..47180)
                     /locus_tag="PC465_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParM/StbA family protein"
                     /protein_id="HDF2649243.1"
                     /translation="MSKLGIDIGNYAVKTSTDDIFESKVTEVKNFGSDSDSIKIGNKT
                     YYLGEGDEEINIVKYEKENFLPLLLGAICRNTDDEVIDLALGLPVKQFGGLRKDLIEK
                     LQGKEYHVEFAKGNETTKRDITIRSVQVFPEGVTGYLYYAKDIVDQVAGRDVVLVDIG
                     GKTTDIALVQGNKATNPYSINVGTINIYDAIKKSLEMDERFLGKVEIKREKIQDYINK
                     GFYLNGEKQDIKKNIDASISLFKEIYNELKLNYPVSTAAVVVMGGGAKLLGEAFKKNI
                     PGIIVMSDVDKHVFANAKGYKKMMK"
     gene            complement(47200..47403)
                     /locus_tag="PC465_001949"
     CDS             complement(47200..47403)
                     /locus_tag="PC465_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649244.1"
                     /translation="MSRIVLTFKNNDKEKAIEKFLDEKLSATAYLKELVWEKMNEKKD
                     NAVVEQKKEIEDPANNFDFGSLE"
BASE COUNT        18907 a         5503 c         7934 g        15155 t
ORIGIN      
        1 aaaacacact ttttataatt ttgcataaaa aaagagtgtt tcatatattt ctaaacactc
       61 ttttctactt tttataatta tctaattgta aaagaagctt cagctggact agagaataat
      121 ataatacctc ctgtacaaac accttttcct ttaaatttag caatatatga accctttttt
      181 agccctttga aacttactac accagtttta gtagttccag ctaatctaaa acttacaaat
      241 tgagatgata caattttgcc agccttatat acatctatat ttccttcaaa tcctaaaata
      301 tttccaagcg tagatgttac tctccaagat aactgcccac cactcattgc agttaaatta
      361 gcagtaccac ctggaacaac aacagattta gtcgaaggcg aatctgagtt tggttggcca
      421 attaattcaa ctgtttgtga atttccagta ccttcataat catttccatc agcaaaagct
      481 gtaaatggaa tcattactgc acaaagcgtt agtaataaag caattgtttt tttcatttgt
      541 tttcccccta tttttttata ttattctcaa ttacagtttc ctttctttac gtgccttaat
      601 aatcatattg taattatact cagcagtttc aaatgctcct accaaaggag ttataattac
      661 actttctatt aagcacaatt catcatagtt taaactagct tctccagcat agaaattatt
      721 taacttatct aaatctattc tagttaaaac ggaaactgat tccattgaga atttgtaaac
      781 atcaataagt ttatataatc cacctatata gttttttgct acttcatggc tcttaaaaaa
      841 ttcatctttt cctgtatgta aatttacttc cataattccc tccattgttc ttatattttc
      901 aaccttcaaa taatatttac ttcttcttca aaacagaata ttctatcacg gtagaatatt
      961 ctgttttttt cattctatca tgatagaata atattttcaa tcatttttta aattatattc
     1021 tatttaaata aaatataata taaaaaagaa cacttaatat ttttcaagct aatatattaa
     1081 gtgttctttt ttatattttt acaaaattat ataaaattat tctttaatca attaaagtgt
     1141 ttttctattt cttaataata agaaatgata taaaattgta tcattttaaa gattttgtga
     1201 tataataaaa gcaagaagaa ctacaatcta tttaggcgta gagtggagtt cataataaac
     1261 atagtttatt ttttgaattt aaatataaat ttaaattcaa cctgtaagtc actctttgca
     1321 cgagagtggc tttttgcttt tttgaatagt ttactgatta agtaaactac catgctagct
     1381 gtcaaactag ctaaaacatt aaacaaaaag ttatccatgt aactcacctc ccctcgaatc
     1441 gttgggagga taatcttttg tacatgaact ccactctata gattgtatat tacgctcttc
     1501 ttgctagatt taattatacc atattttgta atatcagtta agagtttgca ctacaataat
     1561 caggaagctt gttccactca caatcaaccc ctattatttt aagaatatca ttgacttggc
     1621 tatttaaatc tttaatatct gatttagaca ttaaaggatc tttcattatt tcatttagaa
     1681 aaatactatc aatgattaaa catacatttt ctgatatata ttcacgtttt actgaaatca
     1741 atgttccaac tgtactttct tttagtttct tatatgctac actcaatata catggctcta
     1801 aatcaattcc ttctagtgtt gtttcaaaag aatattttat ttttatattt tcatttccaa
     1861 taaatatttc ttcattgttg cttatcttct ttaattttct cattatgcct aacatcttag
     1921 cattcacttc atagtttatt ccacatctct ttgatgccaa actcgacatc aagtctcttt
     1981 ctgaataaat tacccattga ccattatagg aaaatgatgt tttagcgata tccatttctc
     2041 cttttccagt aacattaaat ttaggatcta gtttatttat taagtaaatc tcataaaaat
     2101 ccatagtata tttattatct aattccatat actcaagtct taaattctta ttacaccaat
     2161 tttctttttt attacttaaa tgactagcat gtctatcaca gatattctct gttttcccaa
     2221 cgtataaaca ttcttccgta tctggattaa tatatttata aacataatac attttttatt
     2281 ttctccaatt cttaattgtc atatttacag cccttatata tttcaaataa ttcttgccat
     2341 gtatatccaa cttctagtat gtgaaaaata tcctctattt gttggaaaat ctcagcaatt
     2401 ttatattcaa atgttggcat taattccatt aaattagcca aagatccaat cctaatctct
     2461 aatgttatat ctataagtat ttttttattt gttgctgtat attctttcca tctaggataa
     2521 actgaaatca aagaacaact tccaaagctt tctaatgttt caaaatcata tgatatcaaa
     2581 ttaatatcta gttcattctc acaaaattct atatccatat tttcaaagtt atatagcaca
     2641 cttaaaacat tattttcata taacatttca accttggcat ctaacttttc aattctcttt
     2701 aaaaaattaa tagatttttt acttacttca tatttcatat ctatctttct ttctctgaat
     2761 cttctttttc cctttgtctt ttccttaaaa tcttcttctg aatatgtact ccaatcttct
     2821 tccttgtaat caaaaaagat gtgttcagta tccatatcgc ctttacttag tttattaaat
     2881 attggattta gttcatttat taaataaact tcaaaaaaat ccatattata tctacgtgga
     2941 agttcaatat attttaatat taattcttta gtacaccagt cttcttcttt attactcaaa
     3001 tgagatgaat gccttgcata tatatcttct gtttttccaa cgtataaaca ttcttctgta
     3061 gttggatcaa tatatttata aacataatac attttttatt ttctccaatt tttatttata
     3121 gtaatatcct tcttcattta ctagaccttg atcaaataaa tttctcctaa cagtttcaag
     3181 tctgacagga tctttgctat aatcaacttc tctttcttct tttttaacat cttcatcatc
     3241 ccaatactta tccaattctt ctttaaactt taaatcatct ttttgatgaa ttataacttc
     3301 acttatttta tttgaaagtg ttgatttaaa aaaatcataa ttctttgtat ttataatatc
     3361 agtattatct ctttcaagtg ctatagcaat agacttatta aaagcattca gataaacatc
     3421 tttcttaaaa tcaaactctt taaaatcttc tttaaatagt ttaatcgtcc ctgttgtaaa
     3481 aatattttca tttggtatat aaaaactaaa agacacttca ttgtcctgct tctttttagg
     3541 tatataatct tcaaccaata tatctttatc aaaatatttt ctaggttcat aatctattac
     3601 agaaaaaatt atctcatcta tttttctatt ttttcttttt tcttctttta ttgaaacaac
     3661 catgttgcct tttttattta tttcattcat tgctcttttt agaacatttt gcttaaaata
     3721 tttatattct ggatatacat tatcttttaa tttcaaataa aatcttaatt catctaattt
     3781 atattttatc tctacttcct tattttctct gctccatagc ctaaataaag tgtatagcct
     3841 ctgagtatat gcacctctaa aattaaataa aactgataaa ttaatagctg tatatccatt
     3901 tttctttttc tgcattttta caaaatcagt tatatgattg tatagaactt catgcatcat
     3961 aattgtataa atttggtctg tatgatccaa ttcatatgta ttaattaaac cacttccaaa
     4021 agtttttaac ttgccagttg tctcttctat atagtcaaat tccaagacac tctgttgaaa
     4081 catattcaaa atttctttta tatttttatg ctcataatca ttattgtttt tcataaatac
     4141 ttttagttct tcttttgata tagttgtaac ataagatgaa ttttgctgtt tctgagcatt
     4201 aaaaagtatt ttgtaaaata atttattttc cacatttgta aaatcatatt tactttttat
     4261 taaattattt ggttgcatta aaatttcttt tttttccaaa atctatcacc tcatataaat
     4321 tataatacct aatttataaa aaggtcaact atttttaaaa tacactcacc tttgaccctt
     4381 aaaatgatga cctttgaccc ttaaaatgat gacctttgac ccttaaaatg atgacctttt
     4441 gacccttaaa atgatgacct ttgaccctta aaatgatgac ctttgaccct taaaatgatg
     4501 acctttcatc tctgaaacct agatatacca attattatag cttgtctaaa aactattaaa
     4561 gactttaaaa actgttttaa aaactattaa agactagaaa agatgttctg aactattctt
     4621 ttttttatat taaaaaactt tagtatttat ttttctagta tactttaaac acttactaaa
     4681 aataatttct tataaaacat aacttcttcg gttaaaactt tagaagaaaa taaatacatt
     4741 gaaacaaaaa aagtaaatgt atatgaatat gacaaagaaa aacttagaga agttccaaaa
     4801 ataagaaaag tttatcggat ttgtaatttt gatgagtgga aaaaggaaat tgataaaaat
     4861 aaagttgatt aaatatagct taaaagcatt taaaggcttg tctgacgtgc tttaattaca
     4921 aacttgatgt tatttaccta aaaagataca aatttgctta aaaatggaaa tagaaggtca
     4981 aatataaaaa tagagaacca aataaaacta tattggttct ctatttatct tcttcccaat
     5041 cctcgataaa cttttctaaa ctttttaatt tattttcaga tacttcttca tcatcatgca
     5101 gagcacttat aaaactttca aaagaatttt tgtgaaagaa actaaagaaa cttttagtct
     5161 caacttttaa atattcttct ttttctatta atgctttata atatgtaaat ctatctttct
     5221 taacaacctc taaaaatcct ctaccaacta atctcctcaa gaaagttaac atagttgatt
     5281 ttttccattc gtacttttcg cctaatgttt tcaaaatttc agtagatgca acttcttcat
     5341 cttcactatc ccaaatgtac atcattacca aaagttctga ctctggaatc ttttttattt
     5401 tcaagtacta cacccccgtt ttttgatata ctataatact attacaatag aatttaattt
     5461 acaatgaaaa atgtctaatt atgcattcca attttttcca attaattctg attataaaaa
     5521 atactttaat atgctaatta taaagacata ttataatatt aaataaatta tttatttaat
     5581 attataactt aaaagcagtt cgaaaaaatg tatacaatat aagtgaaagt ctttattgaa
     5641 tgccatttag tacaacaaaa tatttgctat atacctaata aaattctttt gatgtcatga
     5701 tattacagtt ttagacatta gttgtatact ataatatgat tgaggtcatc ataaattaat
     5761 tagaggggga ttttaaaatg tcaaaaatga ttcaatgtaa atcatgttca aaggaaatag
     5821 catcaaatgc taaatcatgt cctaactgtg gggctaaaaa caaaaaacca ttttataaaa
     5881 gaggttggtt tatagttgta gtagttttag ttttattata cgctattggt actagtggaa
     5941 gtggtactga tgatactgct gaaagtaatg atgatggaac aagtaaaaca gctagtgtag
     6001 ataaaccaga agagcctaaa aaggaaaaat atgaaatagt tggagatata acatcagaaa
     6061 ctgatagtat ggcaacgtat ataaaaggtg ttattaaaaa caacagtggt catgatatat
     6121 catatgcaca agtaacattt actttatatg ataaggatgg aaatcaacta ggtactgcaa
     6181 tggataatat aaacgatctt aaaaaagatg gtacttggaa gttcaaagca atgggaatga
     6241 atacagatgg agaaattgca tcttatgagt tatcagaaat aactggtttc taaaaataac
     6301 agatttatat caatcatgaa ggactatgga ctatagaagt aaaattctat ttttcatagt
     6361 cctttcttaa tttattatat aaataaattc tattaatgta aaattaaatt ttaaaaaata
     6421 atttaaattg gtaaaatttg acatttgatt aatgttaaat gaggtgttac aattgtaaca
     6481 taaagaagat atatatcgaa ataatacata taaaatacat ataaaactac gtgcgtaaaa
     6541 tatttttaaa aataatcaaa aatcttaatt ttcaatattg aatacaatca aattttcaaa
     6601 ctcatctagg gcatgacata caaaagcaaa aaacattaat ttagtagctg ataaaagttt
     6661 aaaaattgta aaagggggaa gtctgttatt tttcagaagc aatgtaattg taaaaaaata
     6721 aatcagaata ttttgaaaat atgggggatt ctatgggaga attaaaaaag gaaattataa
     6781 attcaattga aaatacaaat gatgtaaaaa aattaaaatc aatcttaata tttataaaaa
     6841 caattctcaa taaataaagc cgttaaaata acggctttat ttgtctaact ctttcataaa
     6901 attaattaaa aagtttctct gatcttctgt aagtttatta aaagctataa tgacattttt
     6961 catgaattta tcatctgaat taattatatt tgctgctatt tctgcaacta aatcatcatc
     7021 tgatgaatct gcaaacatct tgccttcttt gttcttgagc cattcttctc taacaccaaa
     7081 ttctttactc aattgagacg aaattctatc actcaaaggt ttgccatttt tttctatttt
     7141 agatatagca gaaggtgtca tttttaaaat atttgctaat tcgctttgat ttaaccccag
     7201 tgcctctctt aatgttttta aaacactttc ttcctttatg ttttccaatt ttaatcacct
     7261 cttaagcata attatacaat ataaaaatga aaaattcaaa ataaaaatga aaaaataaaa
     7321 aataattgtg aaattttcat atttatattg aaagtttcac acgaatgatt tataataaaa
     7381 tcatattaca agagaggtga ataatattga aaaagataga tacaaagaaa atatcaaaga
     7441 acataaaaga atcaaccgaa tttggaatat tgtattcttc attaaaagac aagcagagag
     7501 atcgagttct tggaattatg gaaggtatga agatagcaaa tgaattgtca gaaaataatt
     7561 ttatggatat aaaacattca taaattggga ggtattaaag tgaatgatga aatgattaca
     7621 aaaatgttta atttaaatga aacatataaa atgacctcta taagattaaa tttagaagta
     7681 aaaggcgtta ttactcatat agataaaaac gaaatagtct tggaatacta tgacaatgaa
     7741 ttagaatgca ttacaactaa aatattgaca atagatgata taaaatataa tgattacaat
     7801 ctaaagcctt tacactaaga aatgtctttt agaagggagg tgatgaaatg aatctcttga
     7861 aagatgctag aaaaagggaa tggttttggc tagaaaatga agtcatagat aattcaagtt
     7921 taagtatgca tgaaaaaatg gcatatataa cattggcaag gtatgcagac aatgaaagta
     7981 tttgttttcc cagtaatgca actatagcta aaaaaatggg atgtagtata aatacagcca
     8041 ggaaagcaat aaaaaattta gaggaaaagc aattaattaa aaagattcct agaaagaaaa
     8101 atgaaaagga aaatgatagt aatttatatt gtgttatgag cttaaggggt atgtcaagag
     8161 atgatatacc tatagcacca gatgataaag gggtatgtca agagatgata taccctatag
     8221 caccagatga taaaggggta tgtcaagaga tgataggtaa aaagacttat aataaaaaga
     8281 cttatataaa aagtaatact actacacaaa aagaatctaa aactgattat ttagacctat
     8341 catttttaga tttagatata gaaaaagtaa aactaactaa agatgaatat gacaaactta
     8401 taagcaagtt tgggaagaaa tacatacatg ataaaattgt tagtttagaa aactatatcg
     8461 ttaatggcaa agggaagagg ccttatagga tttttgtggc ttggggtatt gttataaaaa
     8521 gaggtataac ctctttttat aactcttcat ttttgatttt tagatatgca ttgtcaatta
     8581 ttttttctat tgcttctcta tcttcatctt ccaatgcaaa tatctttttt atcatagttt
     8641 ttatttcttc actagtttct agatcttctg taatgtcaac gaacatttca ccttctccat
     8701 gcaataacca ttgttcattt acattaaatt ctctacaaat atcatttatg gttctttgtg
     8761 gtatctttct atgccctgtt tcatatgaag agatttgcga aagagacaaa cctaattttt
     8821 tgccaaaatc tttttgtttt aatttctttg aaagccttat atctttaagt cgttgtcttc
     8881 tttcattatc ttctaagttt tgtttttcca taacgtcacc ccttatgagt ataattataa
     8941 catttaaaaa tacgctttgc aattacagat tttaaaaaaa tacgcaaaat aaaataaaaa
     9001 ctcaaagcgt attgacatag tatgcaaagc gtaatataat tgaatcacag gaaggagtgt
     9061 tagaatgaat caagaaaaag aaaaagcgaa tgatttgtta ttaaaacttg aacttcttaa
     9121 aaagataaac ccacaagagt ttggatacat aagcggaaga atagacgtaa atattgagaa
     9181 gttaaaacaa gaaaccgaaa gaaataaaag caaaaaaata agatatagga agggggctta
     9241 aaaattgact tttaataaaa atcaaatagg agcagcagtt caattacaag atataaggtt
     9301 tgatacaaaa gttgattgca tcattacaaa agtagaaaag aatgaaatac tagtcatgta
     9361 ttatgaaaaa gaaacagagg aaatagcata taaaactttg actaaagagg atctaatact
     9421 tgatgattac aaacttaagt tattatatta aaaagtaatt tcggaaggga ggtgattaaa
     9481 tggatttttt gaaagatgca agaaaaaaag aatggttttg gctggaaaat gatttggtgg
     9541 atagagagga tctaagtgtt tacgaaaaaa tggcttatat ggtaatggca agatattcag
     9601 atgatgaaag ttcttgtttc ccaagtttat cattaatatc caagaaaatg ggatgcggaa
     9661 taacgactgt caaaaaaaca ataaatagtt tagaagaaaa aaatttaata ataaaagtac
     9721 atcgcaaggt taaaaacaaa aaggaaaatg atacaaatgt ttattacatt atgagtttga
     9781 aaggtaagtc gtctggcgac ataggtcatg aggcgacaga cggtaggtcg ccatacgacc
     9841 aacaggtagg tcgcgaggcg actagtaaaa agacttataa taaaaagact tatataaaaa
     9901 gtaataccac tccacaaaat gaacctaaaa ctgattattt agacctatca ttcttggacc
     9961 tggatataga aaaagtaaaa ctaactaaag atgaatatga caaacttata agcaagtttg
    10021 ggaagaaata tatacacgat aaaattgtta gtttagaaaa ctatatcgtt aatggcaaag
    10081 ggagtaggta taagagccac tatagggctt tgctgacttg ggggaatgga gatgttagta
    10141 aaggtatagt gtcagaagtt acaaaggcta agaatacact cagtggcttt aaagaacttt
    10201 aaaaattaaa tagataggag acaattgctt atggaagatg aaaagttaga acttactgaa
    10261 aaagatttac actgtattgc aagacattta caaaatgaag ttatggagat ggtgtttaga
    10321 gggaatatag aagcccctac atcatgcgaa gtttgcgatt acttgcaaga atgcaaggac
    10381 tatttcaccc atatagacac ttttataaaa ttaagtgaaa tgacaggtgt agatattttt
    10441 actaaataaa tttagtaaat taaaatttta gtattgtaat tgacgtgctt ttttaaaaag
    10501 aggacagttg ctattagcag tcattatttg aattttgcaa atgtaatttt tattacattc
    10561 gcactctaaa agttttgatc cagcgaatcc aggaaaagtt ttatattcac cagaaaattc
    10621 aactttatcg tcaataagag agcatttttc tcttaaggtt ttaattttgc acatattcat
    10681 caccacccta taattaattt gaacatactg ccaatatgct caaattaatt ataacatgca
    10741 aattatcatg gtgtagaatt aaagcatagg tcaattaaat ttagttataa aatcaatgaa
    10801 acagataaat aattaaatgt taaataaatt agggggttgt tcatgaaaga ggaaaagtta
    10861 gaacttactg aaaaagaatt gcattgtatt gcaagacatt tgcaaaatga agttatggag
    10921 atggtattta gagggaatag agaagccccc acatcatgtg aagtttgcga ttacctgcaa
    10981 gaatgtgagg gagattttac ctgtatgtat cattctttta ctaaattaag caaaataaca
    11041 ggtgtaaaag tgactgcatt taagtattgt tttccagatg aaaatcccaa agctactatc
    11101 taagaagttt ttttagaata ggacattctt cattagaaga agagtcgcaa atatgacttc
    11161 catcacatct agttgacatt aacttagatc caaaagtacc tggaggagct gaatattcgc
    11221 aagtaagaga aatggtttcg tttattacag gacattcttt gcttataact cgatattggc
    11281 tcatactctc accacctttc taattaattt aaacatattg gaagtatgtt taaattaatt
    11341 atagcatgta aattatcatg gtgtagaata gtttcaaatc aaaagaagca actaaatagt
    11401 taaagacagg aggtatgcta agtggaaaga aaaaaacatg aacttacaga tcaagatata
    11461 caaagactta ttgaaggatt aagaactgat ccaaaaataa gagaaatgat atttgaaagt
    11521 aaaggttgtg aaactagaac aagtacaaga agtaaatgcg aacaatttgt tgaagaaaaa
    11581 cttgcttata gaagttatgg atttgaaact ccaaaatact atgcaaaact tattgccgac
    11641 ataattgata ttttagttta caaaaatgtt ccaagagatc gtatttgtgg ggtattgtat
    11701 gacgtcgaaa gggtgattcc tttagttgtg acattttaat aataagctgg gggtgattaa
    11761 atgaattact ctttagaagc agagcaaaac attctaggaa gttttcttat aaatgactct
    11821 ataggttaca aaataaggga attaaaagaa aatgatttct actttgagtc acataaaatt
    11881 attttatctt gtatgaagag aataattgac tcaaataaac ctttagatct tttgctttta
    11941 aaaaatgaac tagaaaaaat agatagatta gtagacgttg gaggagttag ttacattacc
    12001 agtttaacaa ctatagtcat aactacttca aacatagatc actatataaa aatcataaaa
    12061 gaaaagttac ttaaaagaca aatttcagag ttagcaaatg aattgattaa taattcaaat
    12121 tcagatacaa gtatagacga attgattgta gatataaacg atttaaaagc acttgtaacg
    12181 acgagcagtg gcataaatga taattacatt gatgcgtcaa aaataaagcg tgaaaaaggc
    12241 gtacacaagt ccatagacac aggttttaat aaactaaaca atatgctaga tggatttaga
    12301 tatggaactc ttacaatttt gactggtaaa cctgcgtctg gtaaatcaac tatagttaac
    12361 cagtttatag cacaagcaat tacgaatgga gaaaaagcat ttttgtattc tggagaatta
    12421 ccctctttca tggctatgga ttggtttaga aaaactgtag ctaatgatta tcacataaaa
    12481 gaatataaaa gtgtctatgg aggaacatac acagatattc cagattatgc ctctgaactt
    12541 atttcagact ggataaaaga taaatttttt ctctatgacg aagatgcaat aagtgatgaa
    12601 gtaaatctac taaataccat agagcattta tatttaaaaa aaggggttag gttctttgtt
    12661 cttgacaatc taatgacaat aaaaactggc aataaggcag ataaatatga gagacaagag
    12721 cagatagtaa gcaacttaaa aaaccttgct aaaaaatata acttagtaat agttttagtt
    12781 gcacatcctc gtaaaaatat gggtgacatg aagccaacta tgtatgatgt gtctggagca
    12841 agtgagattg ttaattatgc agattatatt ttatcaacat acagggttat tgacgaagaa
    12901 gaagaaacag acgacactta tctattaatt ttaaaaaata gaataacagg aaaacagaat
    12961 ataagtttta aaatgaattt ttcagaaaga agaaaaagac tttacacgac tagtgaggag
    13021 ctaaacagag attacaaata tgatgtaaat aaacaatatg ttcaagtaga aattccagaa
    13081 gatgtatttt aaaaaaaagg ataaaaaata ggaaatttta ttaaataatg attttataag
    13141 aaaaaccaat attgaataat ttaaaaattc aatattgaaa aaaatcattt ttcaatattg
    13201 aaaatcggat tttgaaaaag tattgaattt caatactaaa aaaagtttga aaatatagca
    13261 tttgcaacga ttatataaat taatttcctg acataatacg tacaggttta gatatgctag
    13321 caaaaaactt aaaagtagtg taaggataaa aaggctatat aaatttataa aagttttaaa
    13381 agtgttatta aattagagct aaagtttatt aattaatttc ctcgtagaaa aatattattt
    13441 taaataaata aaggagtgat ttttatgata gcattagaaa aatttgcagg tggagttcta
    13501 aaagaaaagt ttaatacaga gttacaaaaa gttttagata acattgcaga tccaaataca
    13561 gattttaaaa aaacaagaaa aattagttta gaaatagtgt ttaaagcaaa tgaagataga
    13621 gatcttgctg aagtagatat aaaatccaaa tcaactatag tagaagcaaa ggctacaaca
    13681 actaaagttc tgataggaaa agatttagag acaggaagag ttgaagcgtc tgaatttaaa
    13741 aatcaagtag cagggcagtt ggtcatggat attccagata gtgaagaaac taatgaaaca
    13801 gaagaaaata gtgctagtgt aattgatttc agaaatgcaa gttcaaagta gtttaagaaa
    13861 gtaagtaaaa tataaattta aataaaaaag gagaataaaa aaatgataag aaatgcaatg
    13921 gaatatttag ttaagttagg aaaaagagaa acagtatgtg tagatgggtt taagtacaca
    13981 acagatgcat tagaaataat aaaagaacca aaagctaatg aattagaaat aactacattg
    14041 agtggtttag tagattatat aagaagtggc atagatcata aggcagatga gttgttatta
    14101 atacaagttc taactccaag aaaagtgctt ttaaaatctc ctttgagaaa aaatagagat
    14161 agagagacat atattgaatg tgttgcacta ctaccagaga aaagatttga cagaccttta
    14221 gacttagata gttttaacat aatgctacaa tcagcattta taaagaataa tgatagagat
    14281 acacttttaa aaattgcagg aaatatccaa gaatctacag taaaaaatgt gggagatgat
    14341 ggagtttctc agtctgtaac aataaaaaca ggtgtagcta gtgtatcaga agcaatagtc
    14401 ccaaacagag taaagttaat tccttatcgc actttccaag agatagagca accagaaagt
    14461 gagtttattt tcagaatgag ttctggacca gcagcaggat tatatgaagc agatggtgga
    14521 gcatggaaaa atcaagcaat gttaaacatt aaagcgtact tgcaagaaga attaaaagat
    14581 tttaaaaatg taaatataat tgcttaattg aaaatctaag aggacttaca ataagtcctc
    14641 ttagtaaaaa aggaggggat tagatgaaaa tgatttctca tatgaacatt ttagaaagag
    14701 cagaatttac agataaaata gctaatgcaa tcatgtctgc aaataaagaa attgaaagag
    14761 gttgtgcctt taatgaagca gttgagattg taaaacaaat ggaatataga gaaaataaat
    14821 acaatgaagg agatattgca atatgaataa tgtagtttta gttggaagat tagcaagaga
    14881 tccagaatta agatatatac cagagtatgg tactccagtt gctacttttg cattggcagt
    14941 tgataggggt tatgcaaaaa aggatggaac tagagaagtt gattttatac caattgaagt
    15001 tatgggagga tcagcagaat tttgtgctaa ttatctcgca aaaggaagaa tggtttcaat
    15061 tcaaggccaa ataaggatag aaaaatatga aaaagatgga gagaaaaaaa ctttcacaaa
    15121 agtaagaaca aaaattgtta atgcgcttga tcacaagcca aaggatgaag aaaaagaaat
    15181 aggctttcaa gttttagatg atgaagatat tccattttaa attggatggt gattatatga
    15241 gaagtttaga agagaaaaat aaattatttg aagataatat aaatcttgta cattttatta
    15301 taaatagata tttcaaatcc tttttaagaa ggtatccata tttaaaagaa gatttatttc
    15361 aagaaggata tataggatta tataaaacaa catgttgctt tgatgaaagt aaaggaaaat
    15421 tttctacaat agcatttttg tatatatcag gacatttgaa aagatttacg actggatatg
    15481 ttaagaaaca ttatagaaat gatatagata gttttgaaaa gtgtatttat agagataatt
    15541 atggagaaga gataagaata gaagatagat tggctggcaa tgaaaatgta gatatagaaa
    15601 atgttcgtgt tattagatct tgtataaaaa gaagtgagat aaaagatata cagaaaatag
    15661 tttgtctaag agaaaaaggt tatactcaac aagaaataag taaagtgctt ggaactagcc
    15721 aagcgtcaat atataggaga cttaaaaaat taaaaactga aattaatata ctaggtaaat
    15781 aataaatgat ttaagtttat tggaggtaaa atgaaaacta aaataattgg tggtagggaa
    15841 aatgagtgtc caatttgtaa tggtaatata tttaagattg aaacattaat tggaatagtg
    15901 tggcaatgta aggattgtgg atgtatgtat caagatatga gttctaaaga aagtaaaagg
    15961 gggtattaaa gatgagttgt gttataaagt gtgatttttg tggtgaaaca atagcagaaa
    16021 ttctaaacat aaaggtattc agaattgatg atgaaggtaa tataatgagt atcggaaaag
    16081 atgtatgtga caaatgttat gacagattat ttggaagtaa cttgaataag aagatgacta
    16141 attatgaaaa gataaaaaat atgagcaaaa tagaaatggc tgaatttctt gcaaatggcg
    16201 gaagtggatg tactagttgt gcttatgatt ttcaagaatg cttaggcgga tgtttagaag
    16261 gtagaaaaaa atggcttgaa agtgaggcga tgaaataatg aaaaagacgt taataatcgt
    16321 aggagtagtt atttcaatat taattatgct tgcttgcttg ttcttagtaa ctaaaaataa
    16381 agcaattgat ttagaagagc aggtccaatc agcaactgca tctgtagagg tgcaagaaaa
    16441 aaggagaatt gatttaatta agaacatagt agactgcgta aaagactatg ctaaatatga
    16501 aaatagaaca ttaaaagaag taactgacat gagagtaagt gcaaatgatg aatctatcaa
    16561 ggaagcaaaa ttaaatatac aagcagtagc agagaagtac ccagatttag aagctaatga
    16621 aaattataag caactaatga gtgagttgag tataacagaa aatatgattg cacaacatag
    16681 agaaaattat aatatgcaag ttcgcaatta caataaatat ataagaaaat ttccagcaaa
    16741 tttaattcta aatagtatgg gatatgaaaa aatagaatct aaatatactg aatataaagc
    16801 aaaagaggat gcacctcaaa atttatttga ttaagaggtg cacatatgaa atttaaaact
    16861 tttgaaataa ctaagagaga atttttagtg agcataataa ttgcttgcat gatgattgtg
    16921 cttggatttt tcattgatga taaagttcaa tcaaaatttt tagaagataa tgaaagatat
    16981 tacaaagcaa ctaaaataaa taatgacaaa gatctctttg attatgctat ggaaacaagt
    17041 gcgggagatt ctttgataag tggaagattt aaaagtgtag attctgtatc tatagaagaa
    17101 ttaaaagggg actattggtt tatagaaaga acggaagaaa aatacactat gcatactaga
    17161 gtggttacca ctaaagacag tgaaggccat tcacataaat atactgaaac atattggact
    17221 tgggattacc atgattcaat agagaaaaaa tgtaataaat ttaatttcat gggtaaagag
    17281 tttgatgcga aagtaattac taatttatct aaagagagat tggcattaaa gaaagatata
    17341 tttaaaaata ataatcttaa aataaaaggt aattatgctt acattaataa taagagaagg
    17401 tactattatg aagttatacc gaaagaattt aatggtacca tgtatgctaa tttaaaaaat
    17461 aatactatag cgaatccagc tgataaaaac ataaaagttt ttaagggtga atctatacag
    17521 aatgttttgg aaaataacaa ttttaatata ggatttttta aagtagtgtt ttggattatc
    17581 tggatattaa taactacaat cattatatat gtattttatt atttaaaaaa tgattggctt
    17641 gaagataaat aaagatgtaa gaggagaaga tcagacatga aatgtaaagt gtatcatgct
    17701 attaaaaata tgaaagatgc aaatgagtta attgatagat ttgaaacaga aaatatattc
    17761 tttgaattaa atgacataga taatgaaaat gtcttaaatg gagaaatgga tttaactgat
    17821 atagaagata ttgcatcatt gcaatttata ttagatggag acttatttat atttaatagt
    17881 tgtgatgaaa tgatatttat gaataaatac actcaaaaag agttgggact tcaataaatg
    17941 aataagagaa tagtatgtca agatacaaac gagattgtct ataattataa agaatatcaa
    18001 aaaactaaac actgggaatc actaaaaaat gaattctatt tttctaatga atgtaaatgt
    18061 gttttgtgtg attcagtaaa gaaagtgtct ttgcatcata aaacatatcg aagaatagga
    18121 gcggaagaat tggatgattt aattccatta tgcaatagtt gtcactataa agttcatcga
    18181 aataataaac aatatctatt taatgatgca acggaaaaac agataagata tataaatgat
    18241 ttattggaag tttatgtaga tattgtggaa gaattattta tgaatgaata tatttatctt
    18301 tatgttgcca tgggaatagg attttacaat aaaaatctaa tgttatttga agcaaatcat
    18361 attattaatg atcttaagtt tgtttctgca atgctgtatg agttttatgc cacaaagttg
    18421 gaaataaaac ttccaggata tttcaatgga tttgactacg aagaaataaa agattcttta
    18481 tataaaaaga tgcagcgatt aagtaaatat atttatgttc ccaaaaaaca agagattgag
    18541 ttattattta aaaaaagaaa aaaggagcat tatgaataaa tatactcaaa aagagttggg
    18601 acttcaataa ataatagagg agagatatta aaaatggatt tgaaattaat tagcagtata
    18661 cctaattgga aggtagagga tcagttggca aaaattgatg aagaagtaac tgagtttaaa
    18721 gaggctatag atacaggaat aactaaagat ataattgcag aaggattaga tgtttgtcaa
    18781 actattttaa caatgtttca agttttagaa atagaaaact atattactga aggagtagag
    18841 acacataata agaaactaaa tggaagagga tgggatctca aagaaatagg agacgatata
    18901 cttaatttaa ttaaaaattc aatgattaat gaattgatta atatgaacaa gaaattaaaa
    18961 tgccttgatg aaaaagaatt taatgcaaaa atacaatttt tagatgtaga taaactatgg
    19021 aatttgtgca tgcctttagt taacttaagt actataaaag gagttaatga aagcattgat
    19081 gaaatgaaaa tgggagagtt tctaaaaaat attaattaaa gtaaggagat aatataatat
    19141 gttgatagaa gtaactgaaa ataatagaga attaaaagta ggagatattg ttgaaattaa
    19201 tggtggtaat aagttatata tgattctttc tttaaaggaa acaataggtg ggtatgttat
    19261 tataaatatg cagaatggat atggttcatt tggtgtttat aaaagtttaa gtcaactaga
    19321 attagacttg aaggtaagag gttataaatt atatagttct gatgattaca agttgcaatt
    19381 agtgcctaga gaataagata tatttcaaaa aagaaaaaaa aggagcatta cttcacgctc
    19441 ctgcttgtca aaattctaaa accgtcatca caacatcatt ataacataat taggagtgtg
    19501 aggtaatgca atctagcaaa aaagacaatt tgtttagtag tgcagaaggt aagttatata
    19561 attataaaaa aataaaagcg gaaatagaaa aaatagacat tgatatgcag atgataaaaa
    19621 acgactacag aggatgtagt ggagttgaaa ttaaagaaaa gacaggcaag acatatgata
    19681 ttaaaagtgt aattgaaata gagactgaag aaaaagaaaa gaaaattgcc ttaaaagaaa
    19741 aagagaagag acataaagag ttgataatag aaaaaataga taatgcaatg aaaatattaa
    19801 gtgaagaaga aaaaaagata gtacagtata aatacttttc aagtagcagg acatcttggg
    19861 aatatgttgg cagaatgatt ggtttttcag cgagtaagtg taagcaaatg aggtttgata
    19921 ttatagataa gataaaagga ttgctataaa aatgtccgat ttgtgacgat tttaaaccga
    19981 tttatgtctg ttttgtgtct aaaaaatgtc cgatttgtga ccaatttatg tctgttttgt
    20041 gtcttttaat catgataaga ttgtattgtg agaaaaatat atttaataaa aatggcttgg
    20101 aatttacgtt ctaagtcttt tttattgtct agagaggtgt tgaagattaa acgtgatata
    20161 acagaagaaa tttcaagtgc tgtatatgta ccagacaatc taaagtatta cgacaatgta
    20221 atgaaagaaa ctcctggtat gtatggaaga gaatgttctt tagattttat aaagaaaaag
    20281 caagaaaaac tcttgaaact aaaaaagaag gttaagaaaa attatgattc taatattaat
    20341 aagatagact catatctaaa aattttagag aaaagtataa ttgatgagtc tgatcacgtt
    20401 gagttggttg tatttaaatt atatttgcaa ttagaaaatg ttgtaaaagt aactgaaact
    20461 gtaaacgact taggatttag aataaagact aacacttatg caagagaaag aaaatatagt
    20521 acaaatgata taacctctat aatcacagat ccttttactg atgtagttga ggacttaaaa
    20581 atattagttc aagagaggca aagaaaaaat tattatggaa ataaggagtg tttttaatga
    20641 atggaagcac atagtggaca aaaagttaat cccataaaag atatagagga tgtatttaga
    20701 cttttaaatt ttctagaaga atggaatgaa agaaactatt tattagccct ctttggaatg
    20761 tgtactggac ttagggtagg ggatatatta gcacttaaag ttgcagatgt aacagactta
    20821 aaactcgata aaaaaggaaa taaaataaga gtatctaagg attggattag agttatcgaa
    20881 gaaaaaagag actataatag agaggttttt ttatctgatg taataaaaag tgctatagaa
    20941 aattatactc aagataaacc aggagaagaa tttttattta aaagtggcaa gaggaagaaa
    21001 tttaatagac ctatccaaac aagacaagca ggaagaataa taaaaggagc agcaaaaaag
    21061 gtaggaataa aagaaaatgt tgcaacacac tctttaagaa aaacatttgc aaggcatatt
    21121 tatgatgaag aagagaataa gacttatgca ttagaactta taaggaagat tctaggacat
    21181 aagacaatag aaatgactag aagatatata ggaatagata aggatgaaga agtaaaagca
    21241 ataactaaat ttactaataa gttaaagaaa agaaaaagaa attaaaatat cttgtatttt
    21301 atctaaaatt taatatgtta cgtttttcaa caacaggaca ttattagaat gcaaagagcc
    21361 ttaacaatag agtttacaag gaatagaata gatttattaa aatgtctgaa aatatatatt
    21421 aaaggtcatt tattcaaggg atttataggg atgtagatat ttaaatgttt atttagaagc
    21481 tgagtaaaga ggtgattaat tggatgtgaa tgaagttgaa ataatcgata gtagctatga
    21541 aaaaggtaaa gagttgacag aagatcagtg caatatggta actctattga ttacaggtgc
    21601 tacagtaaca gaaactgcca gaattattgg agtaaataga aaaacaatct ataattggat
    21661 gaataaagag catgttagga aagaaatgga cagacggaaa caggagctaa caaaccaagg
    21721 aaatttaatg atattaaagg atttagatag ttatatcaac aatatcaagg aattagctag
    21781 tgacaagagc gataagaggg ttatgttggc agccaatcag tatcttataa atcgtatata
    21841 tggaactcct acaagtacag ttatacaagc agaggataat agtgttggca tgggtatgga
    21901 tgcaacagag atagaagcag ctatagctaa aataagaata agaacaagca agaagtaatt
    21961 agatatgaaa taaatcctgc aagaatatgt tttaattatg ttttaattat gtttgaaatc
    22021 aattaaagca aaacatatat tatatatata tttactttaa taattaaatc atatattgta
    22081 tttaacttta gttatagctg atttaataaa atttagtgag acttaataat taaagtttca
    22141 tacagtgaag tgatatggat tattgtagga tatgcgaacc tattggaaat gctaggttct
    22201 ttttaactat gccgaaaata catatttaag gaatagttga aagataatta ataattgtaa
    22261 ttaaaaaaat attttttgca agaaaataat tcaaaatact ttaatatatt tattttttta
    22321 ttaatagggg gtgtccttct attttgaaaa aattattttt tatgaaaaat gagttctgga
    22381 aattttctag taaaatttaa aaaccagaga catattccag agagggttta ttatagagaa
    22441 aactgtattg tttattttat taactatatt gctaactgaa cctaaaaaga aaatagaaga
    22501 aataaaaagg atgtaaatac gagtggataa tttagaaaga aatatacaat taatatttag
    22561 ttatctagca aagacattta taagaaatgg agcaactata aaagacgctg aaaaagaagc
    22621 aaatgagatt ataaaagcta attcaagtaa tatttgggga gttaatgggc ttgcttatca
    22681 acttggaaaa ataaatctag aatttttctg tatgtatttt atgcaagata catatctacc
    22741 gaaagaagat aatgctgctg ctcctatagc taaagttcat catgagttat gggaagatat
    22801 acaagaatct ataattggag atggtcctca gcaattagga agaatttatc caagaggaac
    22861 aggtaaaagt gcatttggag atttagcaac aactgtatgg tcacattgtt ataagcataa
    22921 aacatatact ttgatttgct ctgatatagg ttctacagca gaaaaattcg taaaagatat
    22981 aaaaaatgca ttacttgaaa atgagtatat taaaaaagcg tttggagttc ttttaaatga
    23041 taatgataga aaatacattt gtaatagtac tcaactagag ctaacaaata aaacttttat
    23101 tgaagccata tcatcttcat cacccatgag aggaagaaaa tacaataaca atcgtcctga
    23161 tcttatcata cttgatgact atcagtcaga agaaaatgtt agaacagaag atgctagaga
    23221 gaaaaaattt aaaagatttt ctgatgatgt aaagtatgct gcacaaaaac cagttatcag
    23281 aaatggtaaa actataaaaa gaggtactac ttttatagca ttaggaacat tgcaacataa
    23341 agaatgtttc tatagtagac taaaaaattt accaacttgg aagtttaaat gtgaaaaagg
    23401 agttttagtc gataacgtag atgaattatt taattctggt ttatggctta atttcaaaga
    23461 gttgttattt gattttaaaa atacaaatca tcttgaagat gctaaagaat tttactggga
    23521 aaatgaaaaa gaaatgaaat tccctatatt atggccaagt ttttgggatt gtttagatat
    23581 ggctttaagt tattatgaaa atccaacatc ttttaaacaa gaggtacaaa atgatgtaaa
    23641 ttcaataggt gagaaatggt ttaaaacaat cagaactgaa tctagagaat atatagaaac
    23701 ccatacattc aaaaagacaa tgctattatg tgacccagca tctgcaggtg ggtctaaaca
    23761 tgactatagt gcttttcttg ttggaagcga atcagaaaat agtttactat atggtaggtt
    23821 ggcggagcta gctaagataa atgctagaac tgattttgat aaatatatag accatatgat
    23881 ttatctatta aaagtgtatc cagatataac gcatgtttat atagaaaaaa atacatttaa
    23941 tggtgcagat gctaatcaat tagaacttaa aataaaaaat gatgatgttc tttactacag
    24001 agatatagaa atcattaatg agcaccaaaa gaaaaataaa gatgataaaa tctctacttt
    24061 aatacctgtt ttaagcaaag gtcaaatggt ttttgcagaa gaagataagg aatttataca
    24121 gcaaatcctt gattttacag gacaaaagta ttctttacat gatgatgctc cagatatatc
    24181 agcagaattt ataaatagaa ttttcaaaat agaagttatt gaaaaagtaa gttttctaga
    24241 tagaagaaag ttaggtgttt aagttgtgaa gttaaatgaa ctaataaaaa atattttcaa
    24301 taagaatgat acattggatt taaataaaac agatcattta gatttagtaa aaaaaatcta
    24361 tggccaacat tatagtaaaa aatatgttta tgaaaaaatg tatcgctatt ataaaggtga
    24421 tactgatgct atgagaaaat ataaatttgt aacagaaaga tctaatctaa aaacaaatgt
    24481 aaattatata aagaaattca taaaagaaga agtatcttat actgtaggta atccaataac
    24541 atatgaatct agaagtggaa acataaattt tgtaaatgat attgaatatt acacaacaca
    24601 ttgggatgaa ttacatgaca gcgacctaat gaaatatctt ttaattttta caaaagtata
    24661 tgaaatttat tatataaata aagaaatgga gttttgttct gagataataa aaccaacaga
    24721 tggatatgct tacaaaaata aaaatggaaa aatcttattt tttatacatt cttttaagga
    24781 tccttttgat tgtactataa actatataga tgtgtataca tcaaataaaa tttatcattt
    24841 tgatgatagt tttaatcaga tatcagagcc aagtacacat atatttaaag aagttccggt
    24901 tactatagga aaattaacat tggaaaatga aaatgatagt ttatacaaag acttaaaagg
    24961 tctacaagat ggatttgaaa caaattttag cgatattgga aatgagataa gtgattttag
    25021 aaatgcgtat ttaactttta taggctgcaa agtagatgag gacgatttac ctaaaatgaa
    25081 agaaaaagga ataatgcaat cttctgatgg aaaaattgag tggcttataa aaaatataaa
    25141 tgatacattt gtgcaaaata cattagatag atatgtagat actatgtatc aaatatcatg
    25201 tcatataaat cataatgaag gattggttag taatttaagt ggagttgctt taaggtccag
    25261 gttgattgcg cttgaaaata aatgtaaatt agaagaatta tctcataaga acattgtaaa
    25321 aaatagaata agatttttat gtaaatatct aaataccatt aaaaataaag attatgatta
    25381 taaagatatt aaagctatgt atacacctaa tataccaatg gacgatttag gaacagctca
    25441 aatgctctct caagcgccag aaggaactat ttctaaagat acagcaagga gtttatttag
    25501 ttttatacac aacacatcaa atgaagcaga taaggttaaa aaagaatttg aagaagagta
    25561 tggtgtgagt gaaaatgaag gcaactagaa ggcaagaaaa agtagttaat ttaatcttaa
    25621 aattttcatc taaattatat gatgatggag aaaaagaaat tgaaaaactt gtaaaaaaat
    25681 ataacgcaga taaagagaaa ttattaaatg aaattgccat gatcttatta aaatataagg
    25741 taattaattc tatgatggat ttaaaaagga ttgaaagaat aagtttatat aagactttag
    25801 ttcatcaaat agatgaattt actcaaatga ataaaaaaac tgaaaaagat gtgttaacgt
    25861 cactattact tagtactgct tatcataaat ttaatacaaa taactatgtt tttattttgg
    25921 ggagtaagtt aaatctaaaa aatataactg acaaagagat aaaaaaaata ctagatgtaa
    25981 gaatagatgg taagttatat tcagatagaa tttataaaaa caaaaatgaa gtttctgcaa
    26041 aattaaaaaa agatatagat aatcttttaa aaggcaaaac aagcataaat gatatagaaa
    26101 aaagtattag taaaagattt ggaactttag aagaggatac aaaaagacta attgagaatg
    26161 aaatttcaag agttcaaagt caagttaatg aactttggat gcagaaaaat aatatacaat
    26221 atgtcattta tagttctgca ttagatcata aagtgtgcga atattgctca cagtatgaag
    26281 gtcaagtatt tttcataaac gaacgacctg tagaattgcc tcagcatgta agatgcagat
    26341 gcatatatat tccaataact aatacatggg aatatacaaa tgaaataact aatataacat
    26401 gggatagcta tttaaatagt attgaatagc ttatttttat gtaaaaatag aaaggattga
    26461 ttaaatgcta aaaaaagatt tattaaattt gattaaaaat gctagcgaag aacaagatat
    26521 tgatgattta ttgaaaaatt ctgatttagc taaaaaattt acaacagaag gactgacatt
    26581 agacaatttt aaagaattat gttctaaaga tgaaatattt aaatcgtttt tagaaaatga
    26641 aaaaaataat gattttgaaa ataaactttc tgagtggaaa aaagaaaatt tagaaaaaga
    26701 actaagtcct tttataaaag agaaatatcc agaattgata gaagatcctg ttcaaaaaca
    26761 acttttagaa caacagaaag aaattgaaag aatgaaagct gaaaatgcaa aaaaagattt
    26821 attaaattta agtatcaaat atataagtga gaataaaaag gctgttccag gtgattgggt
    26881 tgaaaaattt ttaggtgaag attttgaaac aacaaagact aaattagatg aagtctctaa
    26941 aatgatagaa gatagagcga gtttgatgtt tgagtctaaa ataaaagata ctacctatat
    27001 accaggtatg ggaaacaatg gagaaatttc tagtatagga caaatgttag ctgacaatgc
    27061 aaataaaaat agtaaacttg agtctgatcc atgggctaac gaataaaaga ggaggagtaa
    27121 atatgttttt cataaaaaaa ccttacatta atgatttaga agtattagct aattcggcta
    27181 atttagttac tattagtagt acgataaatt cagaaaatgt aaatttaaat tctgaaggta
    27241 aaaaatatgt agtttctgga agtttaattg acttagatgg aaatattgta acagaaatca
    27301 aatctgggtc agaaggttct tttacttatt cattatcttc aactcctatt gggatattat
    27361 ataagactgt taatgtaacc aatgggaata tgtctggagc gttaataatt gaaggttatg
    27421 taagagaaga tagagtttta gaaaacttcg aaaatacaaa agatgaaata aaaaatgctt
    27481 tgccagaaat aaaatttatg taggaggttt atatggctag aattgatgag gtttttaata
    27541 caaaagaatt aataaattat tttaaaaaga gagagtttcc agaattgctt ggtgcaaaat
    27601 tatttccaga aagaaaaata caagatataa gatttgacat gattttagga aaaagtggat
    27661 tacctgtatc tgctgaaata catgctatgg atacagaaac aacaatagca tctagagagg
    27721 caatagataa aggcgcagct gaacttgctt tggtaaaaag aaaaatagca ttaagaggtg
    27781 aggatttgat aaaaattcag tcgcctagaa atgatgctga atttaaatta gcattgcaag
    27841 aaatttacaa tgatgctgag aaaatgtata aagcagtttt agttaaagct gaagcaatga
    27901 gaatggaagt tttggcaaca ggtaagttaa agatagaaga aaataatata aaagttaccc
    27961 taaattatgg aataccaaac tctaatgtta agaaatttaa ttggaaagat gtaaatgtta
    28021 aacctttaga agatatagaa gttcttgtag atactgttga ggatgcaagt ggaaatagac
    28081 caagtaagat gctaacttct agaaaaatat taagaagtat atgctctaaa gaatctgtta
    28141 aaaaagcagt atttggaaca aattcagata gaatagttac gcaagcacaa ttaaatgatc
    28201 ttttaagtca aatgaatctt ccaactatag ttacaaatga ggaaaagtat agagttgaaa
    28261 ctgcaaaagg atatgagaca agaagatatt atccagataa cgctctaact gtgtttgggg
    28321 atggacttct aggagaaaca atatatggct taactccaga agaaattaaa ttaattggag
    28381 atggcaaaat ggatgtggca caaatgattg acaatatatt tgtaggaagt tattcaacta
    28441 tagatccagt tgcaacatat acaaaagctg ctgctactgt tcttccatct atgccacaag
    28501 cagaagaaat tggaatagct acagttgaat tgtaggagga attatgtttg aaaatataaa
    28561 gattatttta aatatacaag acgaaaaata cgataaaata attaatctat atatagaaaa
    28621 aataacaaat atgatactca actactgcaa tagaaaaaaa cttaatgaag cattagaggg
    28681 gtttgtagaa gaaaaagtta taacaatact aacttcaaga tttgatgatt tgaagaaatc
    28741 tagtggtttg gaaaatgaga agagcataaa agcgattacg agaggcgaca caaagataga
    28801 gtataattcc tctgtgacat atgatataag tactagtata agttcatcat cttttttaag
    28861 tgatgtcgat aaaaagtttt taagttcatt ttgtgttgtc agtatgtatt aaggggtgaa
    28921 taaatgactg aagcagatat attagaaatg acctatcttg ataaaatgac tatcatcaga
    28981 aagtcaaaag gttggaatca agaaacatgt tctaatgatt ttagtaatat tattatagct
    29041 gaggatatcc catgtgcaat ttcaagaaaa gaagaagcta ttgtaaatgg tgatattgga
    29101 gctatagtca taaatagaaa gctattctgt agaccagaag tagatataaa aacaggagac
    29161 actataaatg caacttatag ccatggagaa gaagctatat ttaaggtttc tagggcaaat
    29221 atatatccaa gccatatgga aatacctatt acagaagcgg agagaatata atgggaatag
    29281 ataatttagg agtttttgaa gcattagcct tagatttaaa gttaaatgca tcaaatttta
    29341 atagaaaaat caagaagttt acaaataaaa ctgggcaaga actagcagaa aatataagag
    29401 aagaaacgct tgtgagaact gaaaagttaa aaaatggatg ggaagaaagt cagccagaat
    29461 atgatactta tattgttgaa gacaaggttg aatatgcaac tttagtaaat gatggccatg
    29521 caactaaaaa tggcggcatt gttcctggtt cttttatggt tgaaaaggga attgaaaaaa
    29581 caaaagaaaa tatgacaagt gcaaaagcaa atttatttga ttggtaggtg ataagttgct
    29641 tacaaacaga gacattataa tagcagttaa tgaaatgtta aaaaatgagt tcatggatat
    29701 agatattttt attaatgagg ataatataca aggctttgag gaggcttgtt tttttgtgca
    29761 acttttacct gtttctaata atattgcaaa taaaattttg gatactaaaa agatattcat
    29821 agatattgaa tattaccaaa aagctagaaa aaataaatta aatctatatg acatacaaaa
    29881 tagattagaa aaaatattta acagaaatat tagagttaaa gatagaagtt taactataga
    29941 aaatatatct ccatcaatta caaaagattc tgtagggcat aaactaactt ttctaatgac
    30001 tgtatcttat tttgaagagg tttactttag taaagaaaca tatgaaatta tggaaaatgt
    30061 agatttaaag ataggaagtg attaaatggg tttaccagaa attaatattt cttttatcca
    30121 agcaggaaaa acttttgtta aacgttctgg aggtattgta gcacttattt taaaagatac
    30181 aaaaaatata gggctagttg agataaaaga aatggaggat attccagaaa attattctgc
    30241 tagtaattta gattatataa aaatggctat gaagggaaat gtatatcctc caaataaagt
    30301 attagtttat acattagata cagatgaatc aatagatgat gcactagatt ttatagaaac
    30361 ctgtgaattt aattatcttt gtatgccaga agagacagag caggatttac ctaaaatcaa
    30421 agcgtggatt aagaaaatga gagaagataa taaaataaag gttaaagcta ttactgcaag
    30481 taattcagcg gattatgaag gtataataaa ctttacagca actgatattg aagttgaagg
    30541 taagaaatac acttcaaatg aatttctgcc aagaatagca ggttttattg caggaactcc
    30601 atcaactcaa tctgtaacat atgcagaaat accagaagtt actaatatac ctaagttaac
    30661 aagagttgaa gcaaatgcaa ggataaataa tggagagtta attttaataa aagaaagtgg
    30721 cgctatagta atcgctagag gagttacatc ctttacaaca attactgatt caaaaggtga
    30781 tatattcaaa aaaattaaat tagttgatac actagatcaa attcacaatg atattaaaaa
    30841 aataattgta aaaaattata taggaaaaac ccaaaacact tatgataata agtgtttact
    30901 tattgttgca atacaattat atcttcaaga attagaaaaa gatggtttaa ttgatccagg
    30961 ttcaacaata gaaattaatt tagacgctca aagaacatgg ttaaaagaaa atcatattga
    31021 tgtatctaat atggaagaac aacaaataaa agaatataac acagatacaa ttgtattttt
    31081 aaaagcaaaa attaaattaa tagatgccat ggaagatgtg tatttagaca tctctatgta
    31141 gtttggaggt taaaatttga aagctaaaat agacccaagt agaataatat ctggtacatt
    31201 tggagaatgt tggatagatg gtaggcaaat gatggctgta aaaggcttag aggcaaaaat
    31261 tgaattagaa aaagaagagg ttaaagtttg tggacaattg atggttggac aaaaactcat
    31321 tggagcatct ggaaagggct ctgtaaattt atttaaagtg agttccctat ttggagaata
    31381 tgttgaaagt atgttaaatg aaggaaaagc attcaaattt actataataa gtaaattaca
    31441 agacccagat tcatatggag ctgaaagagt tgctctttat ggctgcatgc ttgatgactt
    31501 aactttagca gattgggaag caggaaaaat gggagaaata gaagttccgt ttacttttga
    31561 aagctttaaa tatttagata aaattacaga aaaataggag gatttttatt atatgaatac
    31621 agtagaaaaa ttattaaata tggatgcagg taaattgaaa atgccatcta gtatatttga
    31681 attatattgc aaaaaattag atgatatctt ggaaattgaa tgtaatgcta ttgatccgga
    31741 gcgttttgat gagataagaa tgaactcaat ggatgtagat agtggtaatt tagaaaatat
    31801 taatgtttat gaacttaagg taaatacaat acttgagtca tgcccaatgt ttagaaatat
    31861 ggaagttgta gaaaatctgg gcttggcaac ccctaaagac cttctaaaaa aattactctt
    31921 agcaggagaa attgataatt tatatgagga agttaataaa gtaaatggca tagatgcaga
    31981 gggagataaa aaaagacaaa aagaaagagc taaagatata aaaaactaat taaaacggat
    32041 ggagaagtta acttgatgta cttattattt aagtataaag gtataatgcc atccgtttct
    32101 tatcgtatac taagaggcga aaaagaaatt gttagtgttt ttatggatca agaattagat
    32161 gaaagaaaag aagaaataaa atctggtgct gggaggttat tttaatctat gagttctagt
    32221 acaaaagttt tacaagcagt aataaaaatg agagatgaag caagttcaac tttaagaaga
    32281 gtagcagcta atactagagc tttgcatgat tcatcctctc aagcatcaag agcattaaat
    32341 aatgtccaga acaatttaaa aagtgttggc acaagtgcat taaaagcagg aggacttata
    32401 actgctggag ttggtggggc atttgctgct gcaacaaaag ttggaacaga atttgaaagt
    32461 gctatgtctc aagttaaggc tacatttgga aattccttaa aaccaggaga ttttgaagct
    32521 ctgtctaagg ctgctagaga tgctggaaaa gctacaacta aaactgctgc tgattctgct
    32581 aatgcacttc agtatatggg gcttgctgga tgggatgttc aaaagtcaat gcatgcctta
    32641 atgccagtgc ttaatttatc ggaagcagcc tctatggatc ttggtctagc atcagattta
    32701 gtaactgata gcatgagttc tatgtgctta gaagttgata aagtcagtaa aagtggaaaa
    32761 gtactagctg gtgcaggttt aagtgagtat ttagataaag ttgcaaatgc atctactaaa
    32821 tcaaatacaa gtatacaaca gttgatggaa gcatttaatg ttgcaggtgg tacatttagc
    32881 aatttaaaag ttccgctttc agaagcaact gctatcatgg gaatacttgc aaatagagga
    32941 gttaagggta cagatgcagg tcatgcttta aactctatca tggtaaatct tacaacaggt
    33001 gcaggtcaag caggtaaggc aatgaaaaag ttaggtgtaa gtgcatttga taatcaaggt
    33061 aaatttaaag gtatgtcaaa tgtacttaaa gaagttgcaa ataaaactaa aggtatgact
    33121 gatgagcaga aaaattatta cttatctgct attggtggaa agactcaatt aaaaacgtta
    33181 caaaagttac ttgatggtgt aggaaatgaa tatgatagtt taaagaaaaa aatagataat
    33241 tcaaaaggtg ctttaaaaac aatgtctgat gtaatgaagg ataatactaa gggtggactt
    33301 gcaaccttaa aatcagccct tgaagaaact ggaattacta tttactatca actaaagcca
    33361 gcaatagcat ctgtagttga taatttaact aaaatgactg tttggtttaa taacctaagt
    33421 gaaccaataa aaagagtcat aactaatgta atgctttcag ttggagcatt tggagtactt
    33481 ttattaacta taggggctgt gtctttaatt gtttcaaaag ctataggtat atttggcttt
    33541 tttgttccaa taatattaag agcaaaagtt gcttttagag cttttgtaat tggtatgaaa
    33601 ccattaagtg cagtattttt agctgtaatg ggtcctatag gatggactat aaccgctgta
    33661 attgcattat cagtagcatt taccattgct tatgctaaat ctgaagtatt tagaaataag
    33721 gttaattcat tagtaaaatc atttacagaa tttgcaaagc ctatagtaaa tttttgtatg
    33781 cctgcactta aacagctagg agagaaattt aaagagttgt tatcagcatt tggtccacta
    33841 tttgcgtcta ttttaaacct aggaagtgta ataatgaagg tactaggacc tgttttaatc
    33901 ggcgtaatag gttttcatat agcaaaatta gttttgattt tatctactct ggcaactgcc
    33961 tttaaagctg tggttgatac tataactaat gtattaaatg gtctagcatc tattttaaat
    34021 ggagtatttg atttaattat aggtattgtc acaggcgata gtaaaaagat gatggatgga
    34081 gttaaacaaa tatttgatgg tggaactaaa attataaaat caatttggaa aggtttcata
    34141 gattttgtaa ctgctcctat acaagctata gccgatatag ctgacagctt atttaaagat
    34201 aaagctaaat ggcttacaga taagtggaga gatttaagaa cattcttaga aaatccaatt
    34261 gaagcaactg ccaaaatatc tactaaaaca aatgcaaata tcccaggaag taaagcagca
    34321 gatgcagctg gtaaatctac accaaataca ggtggattaa aacaaacagt agcaaatcta
    34381 aaaggttcat ttagtgattt taaaactttt attaagccta tgacagactc tataagtcaa
    34441 ggagttgaat ctggaaaaac taaatttaca gaactgcaaa acaaaatatt aaatgatgtt
    34501 aaacctgcat taaaggtctt agaggattct ggagtaaatt ttaaagataa gtttaaggag
    34561 tcaataactt caataaagga taaatttaat gaattaaaga acatattagc tggaaatatt
    34621 aaaacaaata tagataattt agtaaaagca tttgaacctt taaaacctca tttagataat
    34681 ttgaaagatt gctttgataa ggttaaaaaa gcaattactg acttttttac tccagccaaa
    34741 caggttggag atacagtaaa taaagtaagt cagccaatgg atagtgttaa aaagtctact
    34801 gatggaatta aactttcttt ccaaagttta attcaagcac ttgctcctgt taaagcttgg
    34861 tttcaaggat ttatgccttt cctatcacaa ataggacaac aacttttacc atctatagga
    34921 attgcaatag ctggtgttgt tggcggaata attttagcat ttacatgggt tttaaataca
    34981 ttaaccgcaa taataacaac tgtttctgga atcataaatg gaattatgtc ttttatatct
    35041 ggaattatta atgttattat ggggcttata acaggaaatg ctgatcaaac tatggatgga
    35101 cttaaacaaa tatttgatag tggagtaggt gtaataaaat caatttggaa tggccttgtt
    35161 gatctagtta gtggcgtact agaacctgta atagatcttg ctgattctct tttcaaagat
    35221 aaagttaaag gggtaaaaga agcttggaat aaacttaaag aattttttca taatccaatc
    35281 aaaggaatga tcgagatagt aaaaagtggt cctagtttac aaataggaaa aggtgcggat
    35341 gctgctggca aaagtccaag aaaagcattt ggtataaata gagttcctag aaatgattat
    35401 ttaataagag cacacgaagg cgagaaactt ttaaccaaac aagaagctaa tcaatacaaa
    35461 aggaatagtt caaatggaag tttatttctt gataaattgg ctgatacaat aattgtaaga
    35521 gaagaggctg acatagataa aattgtaaga aaaataaaca aaaaaatatc tcttgcaaaa
    35581 gttggaggcg ttttgtaaat tatcgtgcta taattgtagt atataattta cagggggtta
    35641 tgttatgaat aaaaaaatac cagcattagc aatattaatt gtattatctt taagtttagt
    35701 tggatgcagc acaaatgatt caaaaaatgg agatagtaaa cctaagcaaa atacagagga
    35761 aattaaaaat cataaaatag gcgaagttgt tgatttggac ggagcaaagg tatctgttaa
    35821 aaatgttaga aaactagaat cagatagtaa tgtatatgca gttgagattg aaatcaccaa
    35881 tacaggagat acagatcttg aaagtgattt ccttcaaaac tacatactaa aaacggatga
    35941 taatacagtt ggaaatgcaa taaataatca agaattaaat ggagaattac tatttgacac
    36001 aatacatcca ggagatacat taaaaggtga gatagcattt gaacttacaa aagatacaaa
    36061 gccaaaaaca attgaaattg cttatgaaaa tgtaggaaaa tatacagtat ttgatttata
    36121 ataattatct taaaagacac ttattgaaat aagtgtcttt tattttagga ggagtttaat
    36181 ggaaatatgg ttaagacaag caaataatac atttaggttt cctgttattc caccctcttt
    36241 tgagataaat ggaagtgcaa caataaatac atctaatatt ttaagtgttg gagatattgc
    36301 agtatttgga gggttagggc ttaaaactat agaactatcc tcttttttcc ctaatcaaga
    36361 atatagtttc tgtaattata atggatttcc aaaaccatat gattgtgtaa atttaataga
    36421 aagttggatg aaagaaggat atatattaag atttatcatt acagaaacta atataaactt
    36481 tgaatgtata attgcagatt ttaattatag agaacaagat tattcaagag atgtttattt
    36541 taccttaagt ctaaaagaat ataggaggat acaaatatcc aaagtaaaca ttaataatga
    36601 tgaaaaatta tcttctgaaa aggatgttca actaacaaaa ggatttgata ctaagcaaaa
    36661 aacgcataag gttgttgaag gagatactct ttttaagata gctaaaaaat attatggcaa
    36721 tggagattta tgggagaaga tttataaagc aaatgaagat gaaattaaag atccatctgt
    36781 aataaaaaat ggttgggtat taataattcc ttaaaatggt ggtgatttat aattaataaa
    36841 atcaaaatac aagttcatat aaaaaacgga aatatatata atgtaactga tttagtggat
    36901 aaatgcactt ggtctggtga ttatagatca ccatcaagaa ctttagaatt ttctataatt
    36961 caatctgcaa gtgatattaa ttttaggcag atagatattc cagtagcaag cacagtttgt
    37021 ttttatgtag atgataaaga actttttaga ggaatgataa tagatagatc taaagactct
    37081 aacaataata atatagattt tacagctaaa gatatgggtt ttttactttt acaaagcgaa
    37141 gtgtcataca attttaaaga taaattggtt gaagatattg caaaacaagt atttttagaa
    37201 aataaactcc cactaggtaa tttacctaag actggagtta aatatacaaa aatgtttatt
    37261 ggcgtaactg gttatgatac tataatgagt gtttatacag aagcaagcaa aacaactaaa
    37321 aaaaagtata tgatagagtc taatcttgat aaatttaatg ttattgagaa gggtgtagtt
    37381 actttaaata taacatttga agaaggcttt aatcttatca atacaaattt ttctgaaagc
    37441 atggagaatg taaaaaataa agtactggtt gttgatcagt atggtaataa gattagtgag
    37501 aaaataaatg actctatatt taaagacgtt ggagtaatta tgcaaaaggt aatacaacaa
    37561 caagaaaaca gtactataga catagatgga gagtttaaag gaatcgaaaa aacttgctct
    37621 ctaaaaggat atggtgatat aacttgtgta actggtagag gtgtaaaagt aaaagactca
    37681 tatacaaaat taattggtct tttttatata gatacagata agcatacatg gcaaaatgga
    37741 gattatcaaa ttgaactaga gcttaatttt gagaatataa tggatgaaaa atctgctggt
    37801 caagatgaac aaaaagaaga tggttcagag tatactggag gaacagaata ctctgctgaa
    37861 tttactgctt attgtcctag aaaatctgaa ggtggagata aagattgtag aggtaaaaaa
    37921 ctagatcctt ctaaaaaaac atgtgctgct cccatggttg gatcatatga gaaatcttac
    37981 tatacaaaag atttcttaaa caaacatcct cttatgagat atggagatga aatacaatta
    38041 gttacaggtg tttcaagtcg agatggaacg tataaagtaa atgataatgg acctgcaata
    38101 attatagaaa aggatggaac atatcatata gatattttat ttggaaatgt tgaagaagct
    38161 aacaactttg gaagaagaaa aggaaagatt ataattggtg gttattctgg aaacatgaca
    38221 gaaaaagcaa aaacagtaat ttcagaagca agaaaacatc ttggaaagcc atacaaatgg
    38281 ggtgggaatg gaccaagtag ctttgattgt tctggactaa tggtatattg ctttaagaag
    38341 gttaatgtta atttaccaag aacctcaagt cagcaatcta aggtaggtaa gaaagtagag
    38401 aaaaataatt tacaggcagg agatttggta tttttccata atccagtcag ccatgttgga
    38461 ctatatgtag gtaatgggga atttttacat gcgccacaaa caggagatgt agttaaaata
    38521 agtaaattaa gtaatagaaa agattttaat acagctagaa gagttttgta aaagaggtga
    38581 tatcgtggca gatccaatca atgaatttat aggaataatg agacaagaag gtaaatttca
    38641 taatgaacct tcttttttta ttggaaaaat taaaagtaaa ttaccagatt taaaaataga
    38701 gataaataac atcatattag aaaaagaaga tatcttgata gatagttgga tgcttgatag
    38761 acagatagag ttatttgata cagaaacaag tcaagaacat aaacatgaaa taaaaaatcc
    38821 ctttatagat acttttgaat ctggagacac agtaataatg tttaaaatag gtgaaaaatt
    38881 tgctgttgta agtaaattgg tgagtctaga tgaataataa tactatattc cctttcatgg
    38941 gtgctccaga ggattatatt tctccagaca atgaagaatt acctattttt aaagaatttg
    39001 cttggaattt tgataaagat gaaaagataa ttgaaaatgg agactttaaa atagttgaaa
    39061 gaaatgaagc aattaaagta tggatttaca aaacaataaa aacagataag tatgttcatt
    39121 taatatatga ttgggattat ggaacagata taaaaaatct aatagggcaa aagtatacta
    39181 aaggtcttac tgaaagtgag gcaaaaaggt atatacaaga agctctatta actaatccat
    39241 atatattaga agtcaatgta gtaaatacag aatttaaaga tgataattta tctataagtt
    39301 taaatgtaaa aacaatttat ggagaggagg agattacttt tgtatagtgg ccaatcattt
    39361 agtaccttaa ataatagaac tttaaataac ataaatctcc ctctttataa aggtcagggg
    39421 tcttctcttt ataatatagt ttctccaata aattcagaac ttgcacaatt atatatagaa
    39481 ctttcttata tacataagag agtttttatc caagataatt ttgacgattt tcttgataga
    39541 agagtcaatg aatttggcgt atatagaaaa ttaggcacag aggcaatagg tgaggtaaca
    39601 tttgagggca aaattggaac tcaaatacca aatggaacaa taatatctca tagtgattta
    39661 ctatttgtaa ttattaaaga tattacaata gatgaagata gtaagttaaa tgtaagccct
    39721 atacaggctt taaagattgg cattaagtat aatttatcag ctaacacaga atttaaactt
    39781 atagaagaga taaatggagt aactaaaatt tataatgaac tgaacctaaa gggtggaaca
    39841 gaaatagaaa ctgatgaaga attaaaagaa aggttctata aaatacaaaa aaatcaagca
    39901 acaagtggaa ataaagcaca ttaccagtct tgggctttag aggttgaagg tgtttataat
    39961 gcaaaagtaa ttcctcgttg ggatggtcca ggtacaatta agattctaat ttatggtcaa
    40021 aataatcaat cagttgataa tgaagtattg caaagatgta ctgaacatat agaagaagaa
    40081 aaacctattg gacctactgt tacaattgtt acaccaagta cttttgatat taatattagt
    40141 gcaactttaa cacttgaaaa tggatatgat attgaatcta taaaagttgt gtttttagat
    40201 attataaatt cttatttaat agaaaattca agagagatta tttatataaa agtaatgagt
    40261 ttattagcaa gcatagaagg tgttcatgat ataaaaaatc tccttgtaaa tgatgatgtt
    40321 aaaaacataa tagttgatga agaaaaagtt cctgctgttt caagtgttgc atttgatgtc
    40381 gaggtgagtt aaattgaagt taattgatta tctaccaagt tttgcaaaca ataaaattga
    40441 catacaaatc caggaagcac ttgaaaatga acttctaaca ttaattgacg aaaaagatga
    40501 tttactagat cagtttttta tagatacagc aacttggggg cttgatgatt gggaaagtct
    40561 cttaggtata aaaataaatt ataagttgga ttttgatact agaagaagta atataagagc
    40621 taaattaaga ggcaagggca caactacaat agaagttata aaagctatat cagaagctta
    40681 cacaaagacc aatgttgatg tagaagtttt tagcaatcta tttagtttta cacttagttt
    40741 tataacaaat aattgtagtt ataacactat tttagaatta gataagaaaa tagaagaaat
    40801 aaaacctgcg catcttgaac acaaattcga gaggatacta tttaacaaaa atgggcttta
    40861 tacaggcgca acaattagca caggagaaac agttacagta tatccttatg tacctagaga
    40921 tttagaaagt tttggggaaa tagctatttg cagtggaaat gatagaacat tagaaaaggt
    40981 aacattgtac cctaaaaaat agaaatgagg tgataaagtt ggcagaacaa caatatttta
    41041 ctttagtgac tgaaattggt aaagcagcga tagcaaatgc aagtattaca ggtgaaaaag
    41101 tagattttgc aaaaatgaag gttggagatg gtggaggtag ctcttatact ccaactgaga
    41161 gtcaaacagc actaaaaaat gtggtttggg aaagtacact tgaacatgca caagcagata
    41221 aagacaatcc taactgggta gtaatacaaa aatttatacc tggtgatgtt ggaggatttg
    41281 aagtaagaga ggtcggatta tttgactcta aagaccaatt attggcgatt tctagttacc
    41341 caacaacata taaacctact gcggattcgg gaactgtaaa agaactctta ataaaagtta
    41401 tattagttgt atctaatgta gctaatatca atctaaaagt agaccctact gtaattttag
    41461 caacacttaa agacatacaa gatttagacg ctaaaattga tacaaccaaa acagaattaa
    41521 caagcaacat agaaactgct aaaacagagt taaatgggaa aataggggat acaacacaac
    41581 ttactacaac agataaaaca aatatagtta gtgccttaaa tgaggtaaaa gctagtgtag
    41641 atagcataga aacaacagca gagaaaacaa gctataataa tgcaacaagt aatcttactg
    41701 ctacaaatgt tcaaggggca atagatgaag ttgttagaaa aatagaaaaa tttaatgagg
    41761 ttaatatatc tatacaaaat gatatgttac ctatttaaga taggagagtg agaaaatgca
    41821 gactgaatgg aactttgggt acaatggttc gccacaaagt gttatattga aacctggtaa
    41881 atataaattt gaatgctggg gttcttctgg aggtatcaac aattcttctt ggtatactga
    41941 tgctaaaggc ggatattcta aaggtgaaat tacattaaaa aaacaaacta cattatatgt
    42001 ttacgtcggc gaaagtggtt ttgcttcttc atctacagct aataacacta aaagtggttt
    42061 taatggcggt ggtaaaggtt atttaaatca acaggttatg ggtacttatt attctatgta
    42121 cggtggtggt gctaccgata taagacttgt tggtggtgct tgggataatg agcaaggttt
    42181 gctatctcgt ataattgtcg caggtggtgg cggaggttca tatcatcctt acactggtgg
    42241 tgcaggagga ggattagaag gaggtactgg gtatagttct aatgacagat accgtcccgg
    42301 tggtactcaa tatcaaggtg gtattggtcg tgtaaataca gaaaacggaa gttttggaaa
    42361 agggtgttct gttaaaaatt caactggcga aggcggcgga ggtggctggt ttggtggtgc
    42421 aggcatgaat ggtgtaggag caggtggagg tggaagtagt tatgtattga ctaaagacag
    42481 ttataagcct actggctaca caccaacatc tgaatattat tttgataata ttgttatgac
    42541 accgggtgga aatactgctg gtgcttatgg ttacgcacaa ataactttac ttcaatcatt
    42601 accattttta aatatatcat cttataattc tacacaagca acattcaaag ctgaccacac
    42661 tgaccctaca ctactaacta aaatagaata ctttatagat gatgtactaa aagaaactat
    42721 aacaacagat ttaacaacag aaaaaataat taactacaca ttagaagata atgcattaca
    42781 cacacttaaa atagttgtta cagacagtaa taatgctaca gcagaaaaag tactaagtat
    42841 aagcaaagga attgcacctc ttcctgctgg ttctacaaca gatgaagtta caaacaaatg
    42901 gatagagatt aaagatacat tcaaaagtgg caaaacaagt attataaata ctttagcatt
    42961 aaagaacata gaagcaagtt taaataatac gctagtagag ttatcagaga aaattaaaac
    43021 ttcttttgat agttcagatg ctagtgttga ggagttgcaa aataggataa cagaattaac
    43081 taatcaatta agtcaacgaa ttaaatatgc gactggcact tatactccac cagatggttt
    43141 tcaaaattct ttaattgttc ctactaaatt aaactttgta ccaaaaacta ttataattag
    43201 ttatatttct tttagagata cttctcaacc ttttaagtat cttcacgctt atccttgtat
    43261 gagtggtaga ggtcgaaatc ttaaatatga taatggttca tatactcgta ttgttgggac
    43321 tgctaatgtt agagatatta ctgccgatag ttttaatatt gaaataggta tcagtgattt
    43381 aagtgctgga attaaatttc ctattagttt ttatactagc acttttagat ggtatgcgtt
    43441 agacatagag cttttaaata attaataata tgaggtgata gaatggatag aggaaataga
    43501 gtaatttata atcaagatgg gaaaatatta ctccaaacag gtgaaacaac aggtgacgta
    43561 ttagaacatg atacaataac agaattacat tacttagatg ttgaatatgg aagtatagac
    43621 tatagtaaac agtatataga gtctataaat ccagttacaa aagaactaaa cataaaaaat
    43681 atagagattg ttttgacaga tgaacaaaag agattacagg cattagaaaa agaattaagc
    43741 atgttaaaag aagaaaataa aaatagagat agtgagatag taaacacagc attcgaagta
    43801 gaaaatatga aattaaataa caatatttag gaggaattaa tatgtataac ttattaaaat
    43861 taatgataga acaaaagaac tatagtacca aagaggattt acaacataag atggatgtat
    43921 tctatgcagt aaataggatt acagaagaac aatatttaga gttaacaggt ttattaaata
    43981 aagaagaaac accagtagaa ccaacagtgt agtaggttct tttttttata gacttagata
    44041 atttctaagt cttattttaa tgcaaaataa ggaggaaata tgaacgtaac aatagttttt
    44101 ttagcaacaa atatatttat aaaattagta atattagcaa tagcatttga tacactgcta
    44161 ggatgcttaa gagcgataaa aacacatcag tttaattcga gctttggaat aaatggagga
    44221 ataagaaaag ttgcaatgat agcatgtgta ttttttctag cagtagttga cattctaaca
    44281 aagtttaact ttttatttat gttaccacaa gattgggttg attttttgcg attaaatcat
    44341 cttggaatat ctgaattttt ctctatttta tttattctat atgaaagtgt aagtatatta
    44401 aaaaacatgt atttgtgtgg attaccagtg cctaaacgat taaaagaaaa aatcggtagt
    44461 ttattagata ctatgacaga tgaattaaat gttaaaggag gtagtaaata atgaaaatat
    44521 gtataacagt aggacacagc attttaaaaa gcggggcatg tacttctgct aatggagtag
    44581 ttaacgagta tcaatacaat aaatctcttg caccagtatt agcagatact tttagaaaag
    44641 aaggtcataa ggcagatgta ataatatgcc ctgaaaagca gtttaaaact aaagcagaag
    44701 aaaagattta taaaatacct agagttaata gtggaggata tgacttactt atagagttgc
    44761 atttaaattc aagtggtgta ggagcctttg gaacagaagt attttactat agtgaaaaag
    44821 ggaaggaata tgcgcaaagg gtagtagata aattatctaa acctttcata agaaaaaaag
    44881 gagataaaga agtaggtaat agaggtgtta aattagataa aagtttatat attttaaata
    44941 gttctaaacc tactgcaata ctaattgaaa gtttcttttg cgataacaaa gaagattatg
    45001 agaaagctaa gaaactaggt catgaaggta ttgctaagtt aattgtagaa ggtgtattaa
    45061 ataaaaatat aaataatgag ggagttaaac agatgcacaa acatacaata gtttatgatg
    45121 gagaagttga caaaatccct gcaactgttg ttggatgggg ttataatgat gggaaaatat
    45181 taatatgtga tataaaagat tatgtacctg gccagacaca aaatctttat gtcgtagggg
    45241 gtggagcatg tgaaaagata agttctatga ctaaagaaaa ttatattatg ataaaaggta
    45301 atgataggtt tgaaacactt tacaaagcat tagattttat tgatagatag attagaaggt
    45361 agcaactagt tagttgttac ctttttttat gtctactttt ctttcttttt ccaaacaact
    45421 tcatatccta tcaaattagc aatagtcaag atttcgctat atttcatagt ctcattattt
    45481 attttttgtc ttaaattttc aactgtatta ttcttattat tatgttcatt cattaaatta
    45541 tttaactcat tcatgctgat attttctttt acaagaatac ttttaatttc attcttccat
    45601 gtcatttttt cgcacctctc ttatttatat aataacataa aaaaattaaa agtaaaagaa
    45661 taatctatac taatcaaagt tatatttttg gaaatcaaag aaaaaacttt gaaaaagtgt
    45721 tgacttagat attcatatag attataatat aattaaagaa agagataaac aaaggaggat
    45781 ataaaaaatg gaaaaattca tcagacttga ttttgataaa ggttttagag gaaaagaaca
    45841 tagaagtagt gcaataggag atggcataag actagatcat ataggaggca aaacggggcg
    45901 tggaagagtt caacacaaaa gaagttgcac tttgactact gcaagtaatg ctggtgtcat
    45961 tggcaaaaaa tttagagtaa gaagattaac tccaagagaa tgttttagat tgcaagggtt
    46021 tccagcaatt caagtagtat tggataggtt ctatcctatc tctacatata agtttcccta
    46081 tatgctgact attttagcta ctaactcatg actaaagtca cgagtgtgcg tagctacttt
    46141 ttaatcaaca acttcattaa tatttttttc tttcaaatca ctccaagtca tataaatcct
    46201 cctcaaaaaa aataatagat tacaaatatc atatatttgc aatctattat acatactata
    46261 aactaaatcc ttttttattt catcattttt ttgtatcctt ttgcatttgc aaaaacatgt
    46321 ttatctacat cactcataac tattatgcca ggtatattct ttttaaatgc ttcacctaac
    46381 aatttagcac ctccacccat aacaacaacc gcagctgtac taactggata atttaatttc
    46441 aattcattgt atatttcttt aaatagagaa atagatgcat ctatattttt ctttatatct
    46501 tgtttttcac catttaggta aaatccttta tttatgtagt cttgtatttt ttctcttttt
    46561 atctcaactt tacctaaaaa tctttcgtcc atctcaagag atttctttat tgcatcatat
    46621 atatttattg ttcccacatt tatagaatat ggattagttg ctttatttcc ttgtacaagt
    46681 gcaatatctg ttgtctttcc accaatatca actaaaacaa catctcttcc tgcaacttgg
    46741 tcaactatat cttttgcata atataaatag cctgtaactc cctctggaaa cacttgaaca
    46801 gatcttattg ttatatctct tttagtagtt tcatttcctt ttgcaaattc aacatgatat
    46861 tcttttcctt gtaatttttc aatcaaatct tttcttaatc ctccaaattg cttcactggt
    46921 agacctaatg ctagatcaat aacttcatca tctgtatttc tgcatatagc cccaagtaaa
    46981 agcggtaaga agttttcttt ctcatattta actatattta tttcttcgtc accttcgcct
    47041 aaataatatg ttttattacc tattttaatg ctatctgaat ctgaaccaaa gttttttacc
    47101 tctgtaactt tactttcaaa aatatcatct gtacttgttt taactgcata atttccaata
    47161 tctataccta atttactcat ttatgttatt tcccccttat tattctaaac ttccaaaatc
    47221 aaaattgtta gctggatctt ctatttcttt tttctgttca actacagcat tatccttttt
    47281 ttcattcatt ttttcccaaa caagctcttt taaataagcc gtagctgata atttctcatc
    47341 taaaaacttt tcaattgctt tttctttatc attgttttta aatgttagaa ctatcctact
    47401 cattcaacca cttccttttt tgtaaaatat tataaaattt attaatattt acatatattt
    47461 taccaaattt tatacagtaa ttcaatagat ttataagat
//
LOCUS       DAMJXI010000027        45097 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.028, whole genome shotgun sequence.
ACCESSION   DAMJXI010000027 DAMJXI010000000
VERSION     DAMJXI010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45097
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.028"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(<1..122)
                     /locus_tag="PC465_001950"
     CDS             complement(<1..122)
                     /locus_tag="PC465_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2649245.1"
                     /translation="MAFFTTAVTGLKTVVTAIGAGVGVWGVINLLEGYGNDNPGA"
     gene            complement(402..2243)
                     /locus_tag="PC465_001951"
     CDS             complement(402..2243)
                     /locus_tag="PC465_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004070263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HDF2649246.1"
                     /translation="MSKIVEGIAKDLKSIPEKLKTKTGNVDKKKLLLMNLPYVLAGYF
                     CDKIAWLWRVSPGQDASAKMMAVMAGMEDLFSNPLPSFYPKDLLIGAGCGVALRLVVY
                     FKAKNAKKFRHGMEYGSARWGNAKDIEPYVDPVFENNVLLTETERLMMSGRPRQPKYA
                     RNKNILVIGGSGSGKTRFFVKPNLMQMHSSYVVTDPKGTVLVECGKMLLKNNYRVKVL
                     NTINFKKSMHYNPLVYIRSEKDILKLVNTIILNTKGEGQQSGEDFWVKAEKLYYTALI
                     GYIWYECVEEEQNFTTLLDMINASEAREDDEEFKNPVDLMFDELEEREPEHFAVKQYK
                     KYKLAAGKTAKSILISCGARLAPFDIKELRDLTSYDELGLDMLGDEKTALFVIISDTD
                     DTFNFIVSIMYTQLFNLLCDRADDVYHGRLPVHVRCLLDEFANIGQIPKFEKLIATIR
                     SREISASIILQSKSQLKAIYKDNADTIEGNCDTTLFLGGKEKTTLKEMAEILGKETID
                     LYNTSDTRGTSQSYGLNYQKTGKELMSQDEIAVMDGGRCIMQLRGVRPFFSNKFDITK
                     HKQYKLLSDYDEKNALDIEKYVKNLCKAKVRDNDTVDEVEDAGVLEA"
     gene            complement(2240..2716)
                     /locus_tag="PC465_001952"
     CDS             complement(2240..2716)
                     /locus_tag="PC465_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HDF2649247.1"
                     /translation="MQEEVTQKTIALVFKSSRLTTDVLKKAMKMYLEHRKQGKQASHG
                     KMAVKDLVGQGMGASSIEVTDNNIKSFEKVAKKYNVDFAVKKDKTVAPPKYMVFFKGK
                     DADVITQAFKEFVKVNEKKHDRISVKEKLAEFREQLGKDKNRERAREHQKDRGQSL"
     gene            complement(2908..3429)
                     /locus_tag="PC465_001953"
     CDS             complement(2908..3429)
                     /locus_tag="PC465_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649248.1"
                     /translation="MGNRKRLKRADRTYKDLKQKQKAKIADGMFEKTCDYYREHGKLP
                     EGEECEKIAGQIYQRVKGIAEKTSFDEIYSLYLYRLPRYEVRIAENGIPEKKKDDADK
                     PKVKRKGMSKKVCPNCGRKMKQQFIGLQHCKCGMSWKKDIGYFERTEDMVFALERRKV
                     GKKTKQCPVIWYR"
     gene            complement(3504..3872)
                     /locus_tag="PC465_001954"
     CDS             complement(3504..3872)
                     /locus_tag="PC465_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004070271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649249.1"
                     /translation="MAEKYITEEQRAGCRKVADAFAELYELTDVVVADAGRFGFVRLQ
                     WFSEGEGFDSAMAFSDSMELFEELWRIWYEHEVLTPVLGTPLAELDYDEIFQTLSKDR
                     QEEILEKKKYFISRCEDAFG"
     gene            complement(3924..4577)
                     /locus_tag="PC465_001955"
     CDS             complement(3924..4577)
                     /locus_tag="PC465_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649250.1"
                     /translation="MESMRDIDRAMEREIAKGSCPLRFVKIDFSDSPYQEIASREKLL
                     EVLSYLLRTGDYGRFAGKGTGNNVYMDMKGKKAAFKRTHSFIDRNNIFSAIRRYGKKI
                     KPDFDGHTYLETVRCCFGLPEGEQEKYRVTYDGQETFALPMSDKYILGLYTHCISARR
                     AVPEDMDIPSTGFSEKERGIASLEGVRDVLFQCLLFDTIKCGEGMLYADLCTIYCLK"
     gene            complement(4578..5681)
                     /locus_tag="PC465_001956"
     CDS             complement(4578..5681)
                     /locus_tag="PC465_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004070583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HDF2649251.1"
                     /translation="MDGTIKFDYYYGIEAEQFSFYRVPRLLIKDARFKELSSDAKLLY
                     GLMLDRLALSIKNGWLDEENRVYIHYTLDNIMEDLGCAREKCAKVIAELDSKKGIGLI
                     EKKRQGLGKPDIIYVKNFATLDAGKEPEKPDNADSSAEVRKPNFKRFDNQTSRSSEIE
                     LQEIRKPNLQEFGNQTSRGSETELAEVRESNPNYNNTNYTNLSYTNPINQSDRETEKQ
                     EPGKLDDDMIDVMDDATAYMEIIKENIEYEHHMKYGDWSDKGLYEELYEVICEIVCVK
                     RRTVKVNGEDYPYELVKSKFLKLNSSHLEYVIGCMKENTTKITNIRAYMVTALYNAPN
                     TMNHYYQQLVQHDMYGGGWEEKGMFQSKAEGDG"
     gene            complement(5699..6589)
                     /locus_tag="PC465_001957"
     CDS             complement(5699..6589)
                     /locus_tag="PC465_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HDF2649252.1"
                     /translation="MGSNKRAGSASKVRIDKFEDLFGGSAEQESSAEQIINAPLTDLH
                     TFKDHPFWVEDDEKMEETTESIRQYGVLVPGIARPREGGGYEIIAGHRRKRGSELAGK
                     KEMPVIVRNYTDDEATIIMVDSNIQREDILPSEKARAYKMKYEAMKHQGKKSGKNTLD
                     EVGEAAGENAKKVQRYIWLSRLSEELLAMVDSKKLGFSQGVDISFLTEEAQQWVQAVI
                     EEKSCNISMVQSAKIKEYGKTGELTLAMVRLILTEEKPKERKVTLKADKISKYFAEDY
                     SSEEIEGIIIQLLDEWKKKQ"
     gene            complement(6579..7364)
                     /locus_tag="PC465_001958"
     CDS             complement(6579..7364)
                     /locus_tag="PC465_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDF2649253.1"
                     /translation="MCKIIAIANQKGGVGKTTTTSNLGIGLAKQGKKVLLIDADAQGS
                     LTASLGYTEPDTLEVTLATIMGDLINDEEVEPTEGILHHEEGIDLMPGNIELSGLEVS
                     LVNVMSREMILRSYIEIVRENYDYILIDCMPSLGMITINALACADSILIPVQAAYLPV
                     KGLQQLIKTVGKVKRKMNPKLEIEGILLTMVDSRTNYAKDISSMLKDAYGSSVRIFTN
                     IIPISVRAAEISAEGVSIYKHDPKGKVAAAYDSLTKEVLADGQ"
     gene            complement(7386..7565)
                     /locus_tag="PC465_001959"
     CDS             complement(7386..7565)
                     /locus_tag="PC465_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649254.1"
                     /translation="MLKVRLMGTKNDINWFGKILRRNPKIEVMEFSDLFSNKGTKKYY
                     RAYVEVKKSNVKEEQ"
     gene            complement(7565..8032)
                     /locus_tag="PC465_001960"
     CDS             complement(7565..8032)
                     /locus_tag="PC465_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649255.1"
                     /translation="MSSTALGAEKAKKIIFISDGHEKFYYEKLKEVRYQDVYHKALVY
                     CLGISNDTRRNIKSIYDFKTGCVKTECLHEGWQTSGSVKVVRMAFNLYCNGTPSVLDY
                     DDAEEQVDECKLYTVEELFCCAYAPYFWQAIQIRYPEYATYNHSLYAMFGGQD"
     gene            complement(8308..9672)
                     /gene="rlmD"
                     /locus_tag="PC465_001961"
     CDS             complement(8308..9672)
                     /gene="rlmD"
                     /locus_tag="PC465_001961"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002846262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDF2649256.1"
                     /translation="MLSKNEMYIVDIVDIGQGGVGVGKYNGITVFVEGGLIQDKVKVR
                     INKVKKNYAVGDIVEIIEKSPFRVKRVCSENLRDCGGCQIQDLDYNKQLEMKTNEVKQ
                     VLSRIGKLEDVEVHDTIGMDNPYRYRNKAQFPIQKNNGIPIIGFYKKKTHDVISTEKC
                     VIQHEINDKIVKIIKTYIRAYKVSIYDEKTHTGLIRHLVTKIGFTTKEVMVVLVANGN
                     KLPYLKELASVLKENIPGFKTLVVNVNQKDTNAILGRENIVIYGDGKINDYIGDLVFE
                     ISPLSFFQVNPVQTKVLYDKALEYANLNDTDTVFDIYCGIGTISLFLAQKAKKVYGIE
                     IIDDAIKDAKINAKLNNIHNAEFYVGKAEEIVPKMYREGKTANVVVVDPPRKGCDEKV
                     LETIVSMNPERIVYVSCNPSTLARDLDYLNVHGFKCVEAQPVDMFPHSTHVETVVLIQ
                     RKDT"
     gene            complement(9847..11607)
                     /gene="pyk"
                     /locus_tag="PC465_001962"
     CDS             complement(9847..11607)
                     /gene="pyk"
                     /locus_tag="PC465_001962"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HDF2649257.1"
                     /translation="MLNNVKKTKIVCTLGPASQSEEVLTQLMQNGLNVCRFNFSHGSH
                     EEHKERIDMAKKVREKLNKPVAILLDTKGPEIRTGNFEDPEVFLEEGQKFTITMKDIM
                     GTKEMCTVSYKGLAEDVKSGDSILIDDGLVGLRVKEINGEDIVCVVENSGIVKNHKGV
                     NVPGVKINLPAITPKDISDIEFGISQGIDYIAASFVRKASDVLAIREVLENNNATDIQ
                     IISKIENQEGVENLDEILKVSDGIMVARGDLGVEIPTEEMPIVQKMMIKKCNELAKPV
                     VTATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGKYPVEAVKMMATIA
                     KRTEETLDYDRLLKENGTNNVTVTDAISHATCTTAVDLNASAIITSTSSGYTARMVSK
                     FRPKSPIIATTNNEKTMNKLALTWGVYPVKSSVAGNTDEVIEKAIEAARQADYIDNGE
                     LVVITAGVPVGVSGTTNLIKVHVISEEIVQGIGVGTQTVEGKVRIIKNGNACVDFNEG
                     DILVSTATDAEMNNYIEKAGAVVTENGGMTSHTAIVGINLDIPVIVSATDITNLVKDG
                     EVVTVDASRGVVYRGSTRVL"
     gene            complement(11659..12618)
                     /gene="pfkA"
                     /locus_tag="PC465_001963"
     CDS             complement(11659..12618)
                     /gene="pfkA"
                     /locus_tag="PC465_001963"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDF2649258.1"
                     /translation="MKTIGLLTSGGDAPGMNAAIRAVVRSAIYYGCKVYGINRGYKGL
                     LEEDLTEMNLSSVGDIIHRGGTILKSSRCEEFKTEEGRLKAVKILKKYKIDCLVVIGG
                     DGSFAGAQKLSDLGFPAIGIPGTIDNDLAYTDYTIGFDTAMNTIIDAIGKIRDTSSSH
                     ERVNIVEVMGRHCGDLALYAGLAGGAETIIVPEVEITVDEVALRLKTTQKRGKRHSII
                     VLAEGVGSASDLEKELKKESGADLRVTVLGHVQRGGSPTVSDRILASRLGVRAVELLL
                     DGKSARVVGIKENKIIDLEISEALAQKKVFDKEAYEMAKILSI"
     gene            complement(12827..16396)
                     /locus_tag="PC465_001964"
     CDS             complement(12827..16396)
                     /locus_tag="PC465_001964"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HDF2649259.1"
                     /translation="MNKDFAHLHVHTEYSLLDGFSRVKKLIKRAKELNMSSIAITDHG
                     CMFGVIDFYKTAIKEGIKPIIGCEVYTAARGLRDKDPNYDKYQGHLVLLAKNMEGYKN
                     LIKIVSTSYVEGFYYKPRVDMEELKKHNKGIIALSACLAGDVARALMNRNYEKAKQFA
                     LDYRDIFGEENFFLEIQDHNLPEQKEVNSGLVKLSKETGIPLVATNDVHYVNKEDSKI
                     HDVLMCIQMGKTLNDPNRMRFGSDEFYLKSREEMEELFPYALEAIDNTVKIADMCNVE
                     FDFNTIHLPKYDVPEGYTPETYLRELCFNGLKERYDNPSNEILERLNYELDVIEKMGY
                     VEYFLIVWDFINFSKENNIIVGPGRGSAAGSIVAYTLKITDIDPIKYSLLFERFLNPE
                     RISMPDIDIDFCYERREEVIDYVKRKYGDDHVAQIITFGTMGAKAAIRDVGRVLDIGY
                     NKVDKVAKEIPFALGMTIDKALDTNPNLKELYDQDPETKEIINISKQIEGMLRHASTH
                     AAGVVISKNPVDEYVPLYKHQDAITTQFTMTTLEELGLLKMDFLGLRTLTVIRDTLDL
                     IEKNRVIKNYTEKIDFSKMDYDDPKVYEMLSSGNTLGVFQLESAGMRSFMKQLKPDNF
                     EDIVAGISLFRPGPMDSIPAYIKNKSNPKDVTYLHEKLKPIMEVTYGCLVYQEQVMQV
                     VRDLGGYSYGRSDLVRRAMSKKKMDVMEEERQYFIHGKFDEDGNIEIAGCIRNGVEEE
                     IANKIFDDMIDFARYAFNKSHAAAYGVLAYETAYLKTYYPVEFMAALITSVMGNTDKV
                     VEYIRECKALEIDVLPPDINKSFSKFSVEGDNIRFGLAAVKNVGVNIINNIIAERESN
                     GLFVDLVDLVKRLDQKDTNKRVIESLIKCGAFDNISENRASLMAGYESLLESVSMDRK
                     KNVQGQISLFDAFGDSEEDSDFQQIYSLPKRQEYEERERLNLEKEVLGMYVSGHPLSQ
                     FEKELQEKTSMDNGKLNSLKEEEESYLQMNETDVIMGGMIVTKTIKTTKRNEIMAFIE
                     LEDLYGAIEIIVFPQLLQKYNVILNEDNIIYVKGTLSIKEGENAKLIAREIKDINDDT
                     DFADRNYNSGRTRNVENIKPESGKKLYLKIDSMSDTDTTNNIVEIAKQYPGNDSIYLY
                     PMDENINGKRKAYKMTGALTCICDEFINNLEELLPKDNIKVKA"
     gene            complement(16553..17500)
                     /gene="whiA"
                     /locus_tag="PC465_001965"
     CDS             complement(16553..17500)
                     /gene="whiA"
                     /locus_tag="PC465_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HDF2649260.1"
                     /translation="MSFSTETKNELARVISGNECCNIAELSALVKSGGSIQIVGYKKL
                     NLKITTELNSIARKVFKLLKKNFNINTTISVNKNQMLKRNNSYVLMVTSEMGSEMLLK
                     KLGILEDKEGFFTINKISENLIKHEGCKRAFIRGAFLGGGSISDPEKNYHMEFVTNNE
                     EFADSLKELINSLGFNSKIVARKNNHVVYIKESEQISDLLSIIGGHHALLSLQNTKIV
                     KEMRNNVNRIVNCETANLSKTVNAAVRQVENIKLIQETIGISSLPENLQEIAKIRIEY
                     EDMTLKELGEMLEPPIGKSGVNHRLRKIEEIATDLKKKS"
     gene            complement(17517..17942)
                     /locus_tag="PC465_001966"
     CDS             complement(17517..17942)
                     /locus_tag="PC465_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF2649261.1"
                     /translation="MREEVSAGGVVLFGNTILLLRKFNGDWVLPKGKVEEGENNQEAA
                     LREVSEETGVKADILKYLGEIHYTFKENWDENRAVHKTVFWYLMQAKNMDTIPQKEEG
                     FIDAKFIHLDRVVDLARYDDEKEIIKVALQEIKKRLKKN"
     gene            complement(18011..19117)
                     /locus_tag="PC465_001967"
     CDS             complement(18011..19117)
                     /locus_tag="PC465_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HDF2649262.1"
                     /translation="MAKLLIIVGILGWIALIVSLFIYKKAKNEKVKLFQRSIVENREP
                     NVVVIGGGTGQSVFLRGLKHTTQNITAIVTVADDGGGSGVLREDLGMLPPGDIRNCLL
                     ALANIEPTMNEVMQYRFTEGLLKGQSFGNLFLAAMNGLYGNFEKAVYKLSEIFAITGR
                     VLPVTLEDVNLVAKLENGNIINGESSIPEESKIQKSSIDKIFLNPKDVKPLKDVIASI
                     YDADIIIMGPGSLYTSIIPNLLVEGIVDAIKSSVAPKVYIANIMTQPGETEGYNVLEH
                     VNAIVKHTDENLIDYVIANNEILPEEMLDLYKQDGAEQVLLDKKQKDKLKEMGIKTVE
                     KNLIEIKNNYIRHDAKYISNIVIELALNHNYNKS"
     gene            complement(19129..19986)
                     /gene="rapZ"
                     /locus_tag="PC465_001968"
     CDS             complement(19129..19986)
                     /gene="rapZ"
                     /locus_tag="PC465_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HDF2649263.1"
                     /translation="MKFVIVTGLSGSGKSETMRALEDMGFYCVDNLPPALITKFAELC
                     YQPNSSIDKVALGIDIRGRKFFEALHESLNYLEKENYEYEMVYLDCNDDVLLKRYKMT
                     RRNHPLAKDMQIPEGIKMERKIMEPLKELSTCIIDTTNMKPKDLKEEIKKIYSSGEDN
                     PNLTISVVSFGFKHGILADADLVFDVRFLPNPYYVEELRAKTGDDKEVRDYVMNSKIS
                     EEFYVKLLDMIHFLVPQYIEEGKQHLVIGVGCTGGRHRSVTITNLIAEDLSNKGYRVV
                     KKHRDSMLR"
     gene            complement(20017..20730)
                     /locus_tag="PC465_001969"
     CDS             complement(20017..20730)
                     /locus_tag="PC465_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HDF2649264.1"
                     /translation="MKILADYHTHTLYSHGKGTIEDNVKVAISKGIKTIGISDHSYKH
                     IAYGVKKKDILKMREEVDYLNDKYTDINILLGMECNILDDKGNIDMDDKFIRDFDYIM
                     AGYHFGSTPTSLRSLLNHCNNYIFKTEKAKEYNTKAVINAISNNDIFIITHPGDKGDV
                     YIEEVAKTAKKTNTRLEINSSHSFLNVNQLNKIKGLENKFIIGSDAHCPERVGDFELA
                     MKTISDSNLDISLVENIII"
     gene            complement(20734..21648)
                     /gene="murB"
                     /locus_tag="PC465_001970"
     CDS             complement(20734..21648)
                     /gene="murB"
                     /locus_tag="PC465_001970"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HDF2649265.1"
                     /translation="MNNQDIYINLLNILSKEDIKVDEPMKKHISFRVGGPADILVRPR
                     TEEQLKNVLKLVKKESIPYLIIGNGSNILIKDGGIRGVVIELADNFNSYEINDTRMTA
                     QSGALLSVLGKALQKQELKGFEFASGIPGTLGGALAMNAGAYGGEMKDIVKSVRLMDM
                     EGNIFELSNEQMEFGYRKSIISKNGYIALSAELELQEGNYDEIKSLMDDLATRRITKQ
                     PLNFASAGSTFKRPTGYFAGKLIEETGLRGLTLRGAQVSEKHCGFVVNQGEASAKDIL
                     DLIYVIKSAVYAKFGVMLEEEVKILGED"
     gene            complement(21921..22691)
                     /locus_tag="PC465_001971"
     CDS             complement(21921..22691)
                     /locus_tag="PC465_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDF2649266.1"
                     /translation="MSKGFLTPGETAQATISAGIKKANISTQNAILLGLFGGAFIGFG
                     ALGSMIVSQTFGKVDPGVASFLSAMVFPVGLMLVVVAGAELFTGNTLMAIALMDKKIT
                     LGKMLRNWGLVYFANLVGSILLVALVFYSSTLTGDAATKAIAVAEAKVNSTIASMFLK
                     AILCNILVVLAVWMATASQDIMSKLASCWTVIMLFVLCGFQHSVANMFFIPMGMALGA
                     NITMVQFITNLVFVTLGNIVGGSIVVGGIYYLCYVKNS"
     gene            23009..24490
                     /gene="cls"
                     /locus_tag="PC465_001972"
     CDS             23009..24490
                     /gene="cls"
                     /locus_tag="PC465_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDF2649267.1"
                     /translation="MFDISFFEMSIYEIAVTTIYIINFMVILNLIFREKRNINTTLTW
                     LLILVLIPALGFILYIAFGRNISKNNMFRLKEKDDKIIKSNILDTQVKLQSTSEIDSD
                     IHQHKDMIYALANSNNAHYTNNNDVWIYAESSQFFNSLLEELKKAKKYINIQFYIFKD
                     DKIGTEIIDILIDKAKEGVEVRLLFDAVGGRTLKNSTLSRLKESGVKVGSFFPSFLKI
                     VNFNLNYRNHRKIVVIDGKVGFVGGYNVGDEYLGRNPKFGLWRDTHTKLTGDCVIDLN
                     MRFILDWRYTTKEDLDLEKYFIEEDTNSNHPSENIGIQIVSSGPDISELDEIKYGYLK
                     MIQKARKYIYIQSPYLILDSTFIDTLKIACLSGVDVRVMIPSKPDHPFVYWASYSYAG
                     ELLKFGAKIYTYGQNAFLHAKTIVIDDSICSIGTANMDIRSFELNFEVNAFMYSSKKA
                     LEQRIIFENDILNSKEITLDIYNSRSTYIKIKESISRLLSAVL"
     gene            24808..25305
                     /locus_tag="PC465_001973"
     CDS             24808..25305
                     /locus_tag="PC465_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HDF2649268.1"
                     /translation="MCDFISHNKQLFDELDIFIDSLATKEGALIQVLHEAQGIFGYLP
                     KEVQLHVARKLGVAPAKVYGVVTFYSYFTTEPVGKYKISVCLGTVCFVKGADKILSAF
                     EKQLGIKVGETTSDFKFSLEGLRCLGACGLAPVVTVNGKVYGKVKPDQVSEILDTYRE
                     LELNC"
     gene            25322..27208
                     /locus_tag="PC465_001974"
     CDS             25322..27208
                     /locus_tag="PC465_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HDF2649269.1"
                     /translation="MRKVNSFDELKVLADELKPNLSLRKNYSKENVLRRELLVCCDTG
                     CTSSNSLEIVSELENEIKKSGIQDKVSVRLTGCFGFCAQGPIVKVYPDNVFYVKVEPS
                     DAEKIVQSHLIRNTVVEELLYEEESLSKKVEEQEEMSFYKKQLRIALKNCGLIDPDSI
                     EEYIANDGYLALGKCLTSLTPQEVIAEVKTSGLRGRGGAGFPTGSKWEAASKNPAGPT
                     DKKFVVCNADEGDPGAFMDRSVLEGDPHSVLEAMAICGYAIGSDTGYIYIRAEYPKSI
                     ERLKVAIAQAEKYGLLGENILGTGFNFKLELKYGAGAFVCGEGTALMHSIEGRRGEPR
                     MKTYSSSKSGLWKSPTCLNNVETFANIPAIILKGGDWFANLGTEDSSGTKVFALGGKV
                     ENVGLVEVPMGTTLRDIVFEIGGGIPEGKKFKAVQTGGPSGGCIPTEHLDTPIDFGSL
                     SSIGSMMGSGGMLVLDESDCMVDIAKFFLEFTVEESCGKCTPCRIGTTRLLEILTKIT
                     EGNGTLQDLDDLENLAETIQTASLCGLGKAAPNPVLSTLQYFKDEYIAHVVDKKCPAG
                     KCQNLLSYFITDDCKGCTKCSRVCPAGCITGSVKEQHTIDTSKCLKCGACIDNCTFNA
                     IIKK"
     gene            27231..29012
                     /locus_tag="PC465_001975"
     CDS             27231..29012
                     /locus_tag="PC465_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HDF2649270.1"
                     /translation="MSLVNLTINGKHVSAPSGTSILDAAKLINIKIHNLCHLHMNEID
                     KLDTCASCRVCMVETERGLVPACGTVIKEGMKVQTNSAKALNARRTIVELLLSDHPQD
                     CFVCEKNGDCELQTIAADLGVRKIRYQGSKSFAGKDTSTKSLVKDHSKCILCRRCETV
                     CNDIQTVGALSGVNRGFNTLVSTFFNSDMVETECTFCGQCISVCPTGALTEVDNVPKL
                     WDVLNKKEKTIVVQVAPAVRVAIGEEFGLEPGSISTGKMVAALKALGFEHVFDTNFGA
                     DFTIMEEATEFIERIQKGENLPILTSCCPAWVNFLEHNYPDKLNLASSCKSPQGMFGS
                     IAKNYYAPKILGINPEELYVVSVMPCVAKKYEASREELSESGILDVDLSITTRELAKM
                     IKEAAIDLPNLQDQDFDNPLGKSTGAASIFGASGGVLEAALRTSYEKITNKTLDNVNF
                     TNVRGLKGIREASIDVDGTTVNVCIVNTLKNARKIMDKVRSGECKYHIIEVMACPGGC
                     VGGAGQPYHHGNTEIVDRRANALYEIDRNKAIRKSHENPDLQAIYKDFFGEPNSDVAH
                     KYLHTHYFDKSCVYGECPQECACEEAK"
     gene            complement(29152..30948)
                     /locus_tag="PC465_001976"
     CDS             complement(29152..30948)
                     /locus_tag="PC465_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate oxidoreductase"
                     /protein_id="HDF2649271.1"
                     /translation="MGIEYFSKLLESSTEKELLLSKKSNNISTARLISFLIVIAGFAI
                     GFYNKNIVGIFVGVLSIIIFIALLVIHSKVKEEETYFKSKSEVLNKYIKRFGDGWKEF
                     KIDGKEYLKDENSQAKDLDLFGRASLYQYICVANTSYGKNFLAKYLWNENPDENVILE
                     RQRAIKELLSKDDFSIHIQTLSNIIGKEQKNNSDSSIESFIEYGENKNVYIPKWMHIF
                     TWGLPTATILSFIFCMLGFLPVLPVFLLFIIQLGFSGFGYPRLMQTLAPLFSFSRSIQ
                     VYEKMFEVLEKETFESAYLKELQDKLSKGSGVSRGVKQLNSIGNAVNLRYNQILYIIA
                     CGVLMWNYHCAEALERWKGIYGNQIRDWFESIGEFEALISLTVVSHVKENTCFPVIKY
                     EDTPRLKVEEVYHPLIAEKSVIANSIQLNSQTCIITGSNMSGKTTFLRSIGVNLVLAY
                     AGAPVCAKSFDATCMAIFTSMRIQDDVSQGISTFYAEILRIKSMIQYSLKELPMLVLV
                     DEIFKGTNSADRIIGASEAVKKLSKPWVISMVTTHDFELCDLSGSGDVEVVNYHFSEY
                     YVDDKIHFDYKIKDGRCKTTNAKQLMRMAGIL"
     gene            complement(31160..32089)
                     /locus_tag="PC465_001977"
     CDS             complement(31160..32089)
                     /locus_tag="PC465_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HDF2649272.1"
                     /translation="METSNKVSIREIIKELKLKVVYMPDDVDYYVYSQDINRPGLQFA
                     GYFDYFAYERIQIVGKTEYNFFGLMDSHIREEVLDRFFSYEIPALIISRDLEIKPDVI
                     EKAKKYKRILLSTNRNTTRLINRLSNYLDNKLAPHTTIHGVLVDIYGIGVLIKGESSI
                     GKSETALELIQRGNRLVADDAVEIRKLDESMLVGQSPELIRHFLEIRGIGIIDVRSLY
                     GVGAIKNSKMIDLVVHLEAWDETKYYDRLGLDKEYEEILGVNVEKLVVPVKPGRNTAM
                     ILEVAAMNFRQRGMGYDAAQEFTKKLSKLIDTK"
     gene            complement(32089..33906)
                     /gene="uvrC"
                     /locus_tag="PC465_001978"
     CDS             complement(32089..33906)
                     /gene="uvrC"
                     /locus_tag="PC465_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HDF2649273.1"
                     /translation="MFDIQEHLKKLPSEPGVYLMKDKYDHIIYVGKAISLKNRVRQYF
                     QSSKNHTSKVKSMVKNIYKFEYIITDSELEALILECNLIKRYRPKYNVVLRDDKTYPY
                     IKVTTNEDYPRILKVRRVLKDKAKYFGPYTNITAVNDTLELISSTYPIRSCKIDIDKA
                     IKNKTRPCLNLHINKCLGPCTGNVSKEEYGKMIEEIIMCLSGKEEKLMELLKEKMNES
                     SMNFRFEEAAVYRDKIKSLEEMIQKQKIDATVSDLNQDVVAMARAHNEACVQVFFIRN
                     GKIVGREHFILEGVMDSPRASILSSFVKQFYNEQEYIPKELIIEDEIEDSSILEEWLS
                     SKKGQKVTIRVPQKGEKKSLVEMVRKNAVEYLEKFSDMNKRKYEKSIGALEELKQILN
                     LEKLPIRIEAYDISNIQGVDSIGSMVVYTNAKKDKKEYRRYKIKTVIGPNDYDSMAEI
                     VDRRLKHGNLPDLILLDGGKGQVSAVKKVLELNDVDIPLWGMYKDDKHRTKGLICKEK
                     EIELDKTTNLYRFIASIQEEVHNYAITYHRSLRNKALTKSILDDIQGIGEKRKKSLLN
                     HFKDVDAIKKATMEELLEVDGMNKSIADNVYNFFRKEEN"
     gene            complement(34165..36990)
                     /gene="uvrA"
                     /locus_tag="PC465_001979"
     CDS             complement(34165..36990)
                     /gene="uvrA"
                     /locus_tag="PC465_001979"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF2649274.1"
                     /translation="MEDKIIIRGAKEHNLKNIDLELPRDKFIVFTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMEKPNVEYIEGLSPAISIDQKTTSKNPRSTVGTV
                     TEIYDYLRLLFARVGDVYCPTCGEKISQMTIQEIVDKMLDFPDRTKLQILSPIVRGQK
                     GTHKKVFDNIKKEGFVRVRVNGENYEVSDDIILNKNQKHNIEVVVDRIVIKDGIESRL
                     ADSIETAVKLSDGLVIAQIIDGEEILFSTKFACPEHGIGIEELSPRMFSFNAPFGACD
                     VCNGLGESKEVDPELVVPNKDLSIKQGAVAAWGSTGVNDDTYYSKMIKSLAEHFNVSL
                     TTPFKDLPDDFVEELLYGKDNIIVEFTYESKFGGTRNYKSYFEGVIVNLERRYRETNS
                     DYMRDKIEEYMAERPCPKCKGMRLKKEVLSVLVDGKNIMEVTNLSVNELIDFMENINL
                     TEKQRFIAHEIIKEIKGRAMFLRDVGLDYLNLSRKAGTLSGGEAQRIRLATQIGSALV
                     GVLYVLDEPSIGLHQRDNDRLITTLRHLTDLGNTLIVVEHDEDTMREADYVIDIGPGA
                     GIHGGEIVAQGTLDEIIENENSITGQYLSGKKQILLPETTREGNGSFIEIVKASENNL
                     KNIDVKFPLGKFTCITGVSGSGKSTLINDILYKGVASKVNRLKQRAGKHKEIKGIESI
                     DKVINIDQSPIGRTPRSNPATYTGVFDFIRDIFASTNEAKARGYKKGRFSFNVKGGRC
                     EACKGDGIIKIEMHFLPDVYVPCEICKGERYNRETLQVKYKDKTISDILDMNVEEAVE
                     FFENIPNIKRKLETLMDVGLSYIKLGQPSTQLSGGEAQRIKLAAELSKRPTGKTLYIL
                     DEPTTGLHMADVDKLIQVLQRLADTGNTIIVIEHNLDVIKTCDYVIDLGPEGGDKGGT
                     IVATGTPKEVSKVDGSYTGQFLKKYFS"
     gene            complement(37009..38979)
                     /gene="uvrB"
                     /locus_tag="PC465_001980"
     CDS             complement(37009..38979)
                     /gene="uvrB"
                     /locus_tag="PC465_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HDF2649275.1"
                     /translation="MDFKIKSDFKPTGDQPEAIKSIVDSINRNEKFSTLLGVTGSGKT
                     FTMANIIQQVKKPTLIMAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYVAH
                     SDTYIEKDASINDEIDKLRHSATASILERRDTIIISSVSCIYGLGDPKDYKELMLSIR
                     PGMQRDRDDVIKRLIEIQYERNDINFTRGTFRVRGDILEIFPASNDEKAIRIEFFGDE
                     VDRITEIDYVTGKIVGTRNHVVIFPASHYVTTPERIEKAIVEIENELQEQIKFFKEND
                     RLLEAQRIEQRTKYDIEMLKEIGFCQGIENYSRHITGRSEGERPYTLMDFFPDDYLII
                     VDEAHVTIPQVRGMYAGDRSRKTSLIENGFRLPSALDNRPLNFQEFEGNINQMLFVSA
                     TPGPYEIQHSETIAEQIIRPTGLLDPIVEVRPINNQIDDLVGEITKTIEKNERVLITT
                     LTKKMSEDLTNYLKEIGIKVKYLHSDIVTLERTEIIRDLRLGKFDVLVGINLLREGLD
                     IPEVSLIAILDADKEGFLRSETALIQTIGRAARNENGRVIMYADRITDSMQNAIDETK
                     RRRDIQNLYNEEHNIIPKTIQKNIRDSIEATKVAEEEVVYGISDTDDKDEIRANIDKL
                     KSEMMEAAQNLQFERAAELRDKVKQLEEKLEK"
     gene            complement(39166..40428)
                     /locus_tag="PC465_001981"
     CDS             complement(39166..40428)
                     /locus_tag="PC465_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HDF2649276.1"
                     /translation="MTKVIVLSVDSLFEKDLEFVKNLPNFKSILENCSIVKNINCVYP
                     TLTYPCHTSMVTGVYPKKHGIYHNEKFDPNKENKDWYWYSKDIKAKTIIDVAKENNLT
                     TSSVLWPVMGANPNIDYNIAEIWAPSREDDPRETFERSSSKVIMDGIYNRHCHYIDWK
                     LEPNMDLFGVNCSVDIIKEYKPDLMLIHLATLDHTRHNYGLFNDEVDKALKMNDKWLG
                     DIIQATKDAGTYKDTNFIILGDHGHLRVDKVINPNVLLKSNGFIKVENGEVKDFDAYV
                     NSSGISAQIIVNNLDRLTELRELLEEFKEELFIENIFTKEEASNLGLEGDFEMVIEGL
                     EGISFGNDFEGSIIKDSDIKDYKFAVATHGHLPTKGNRPPFIAFGPNIKDGVVIEEGD
                     LRAHAATILKMFNLKLDGVEKEAFDFIM"
     gene            complement(40491..41795)
                     /locus_tag="PC465_001982"
     CDS             complement(40491..41795)
                     /locus_tag="PC465_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2649277.1"
                     /translation="MKLKRKLATGLAITLLLGSLVGCSNSNDANASKGEKTDSNITKI
                     DFWAPLGGTNGETAQKMVDQFNSEHKDVQVNMLKQKDYYENATKLQAALTSKDQPDVT
                     LLEITQTGTFASAGALVDMSKYFDKTYQERFFSGLLTNSYYEDKFVGMPFNRSTPILY
                     INKDMATKAGLDPSGPKSWEELKDYASKMTNKSEDTYGFETPIDIWFYEAMVMQSGGE
                     ITNGKKVAFNNEAGQAPVKFWQDMMKAGIMKMPPGEDYNAWDVAKQDFVNGKVGMIFT
                     STADLAGLMQQTEGKFEISTAFLPKNQKYATPTGGANLVMLEGGTDKEKEASAEFIEW
                     MTQTDKIVQFSSSTGYLPTTEDATNSEKLQTLYKEKPQYKVATDQLQYAVALPMLNGY
                     KEATDKLMDEIKKGLTDLNANPKDVVSKGTSAMQAVIDKTNK"
     gene            complement(41826..42686)
                     /locus_tag="PC465_001983"
     CDS             complement(41826..42686)
                     /locus_tag="PC465_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDF2649278.1"
                     /translation="MDIIQPIKKDKVDIKKIASKSIEILILLLLSAIFIFPFIWMLST
                     SFKNPQEMMQLPPTIIPNDIVLENYSTAWHSGPFFRYLLNSVFVTGSVLIVQFLVMVP
                     AAYAFSKIKFKGEKMLFGLLLVGLMIPPQVTFLPVYMMMSKFGFINTYVPLIIPFMTS
                     SFGIFLLRQNFMQISDEIIEAAKLDNASDLKIMFRIMVPMAKPAVITFILFNFIYHWN
                     NYFWPLVMTNTDAIRTLPIGVALLKSSEGITAWNVIMAGNIILILPIILVYIFANKKV
                     KEAFMYSGIK"
     gene            complement(42730..43599)
                     /locus_tag="PC465_001984"
     CDS             complement(42730..43599)
                     /locus_tag="PC465_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDF2649279.1"
                     /translation="MKKQFNKAYLYITPAIIGTLLFIVYPIIKTISLSFKSGSLLSST
                     FENVGLNNYTELLKNPEFIQTITNTAIYTFFMVTISISLAIVLAVWLNKNSIIHNLTQ
                     SIIFTPHVISLVSVAVLWLWIMEPQYGFLNWILSTLHLPTSKWLSSESSALMSLILIG
                     IWKTLGYNILIVLSGLKSIPNYIYEASKLDNANKITNFFKVTLPLLSPTIFFLMITTT
                     TASFQVFDEISIMTQGGPVGSTNMLSYYIYESGFIYYDIGQASAASMFLLAIVMIATY
                     ANFRLLSKKVHYQ"
     gene            complement(43583..44653)
                     /locus_tag="PC465_001985"
     CDS             complement(43583..44653)
                     /locus_tag="PC465_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2649280.1"
                     /translation="MADIRLENVTKSYNKKNTVIENLNLTIEDGSFTVLVGPSGCGKS
                     TTLRMIAGLEDITSGRLKIEENDVTKTDASKRDIAMVFQNYALYPHMTVRENIEFGLK
                     NKKVEKEKREKLITEVIDVVGLREYLNVKPGNLSGGQRQRVALARAMVKNPKVFLMDE
                     PLSNLDAKLRNQMRTELIQLHQKLKSTFVYVTHDQVEAMSMADKIVIMNKGKIMQIGS
                     PKKIYQNPKNLFVAQFIGSPCMNILDIKNDIKFGFRPEKATLESINIDGKNDDVFSLF
                     GKVVTKEVLGNETIYCLSVLNREIRVKTENDIFDIGRTLRISVLEKDLYYFDKNGERI
                     EDVKVCKSMYSKIKGDIYEKAI"
BASE COUNT        13217 a         8891 c         5984 g        17005 t
ORIGIN      
        1 gcacccggat tatcatttcc atatccctca agcagattga tgacgcccca tacgcccacg
       61 cctgcgccga ttgctgttac gactgtcttt aatcctgtta ccgctgttgt aaaaaatgcc
      121 attgttctac ctctttcttt ctcatcaaat gttttgtctg gtttctgaaa gagtttttcg
      181 tgtaaaatgc cctgccttat ggtaagataa agacagggca atcctttggg aagaaccctg
      241 cgggcatccg gtacattcag tttggcgatt ggctgtgccg ggtgctttgt ttttgtcctt
      301 tcccaagtac attcaaaact cctttccact tctggacttt ttgtccaaaa gttctgtgac
      361 tggttgacgg gttccatatt cagtttttca gtattcagtt gtcatgcttc aagaacgccc
      421 gcatcctcca cctcatcaac ggtgtcattg tccctaactt ttgctttgca caggttcttc
      481 acatattttt cgatgtctaa ggcgttcttc tcgtcataat cggacaggag cttgtactgc
      541 ttgtgcttcg tgatgtcaaa cttattggag aagaatggtc ttacccctct aagctgcatg
      601 atacacctgc ccccgtccat aaccgcaatc tcgtcttggc tcataagctc tttcccggtc
      661 ttttggtagt tcagaccgta ggactgcgac gtaccccttg tatccgaggt attgtaaagg
      721 tctattgttt ctttacccag aatttccgcc atctctttta aggtggtctt ttccttccct
      781 ccgaggaata aggtggtatc acaattccct tcaatggtgt cggcgttatc cttataaatc
      841 gctttaagct gcgacttcga ctgcaaaata atggaagctg atatttcccg gctgcggatt
      901 gtagcgatca gcttctcaaa ctttggtatc tgcccaatgt tcgcaaactc atcgagtaag
      961 cagcgtacat ggacaggcag ccttccatga tacacatcgt ctgccctgtc acagagcagg
     1021 ttaaaaagct gcgtgtacat gattgataca atgaagttaa atgtatcgtc cgtatcggag
     1081 ataatgacaa acaacgctgt cttttcatct cctaacatat caagtcccaa ctcgtcatag
     1141 cttgtcaggt cacgcagctc cttgatgtca aagggcgcta aacgtgcgcc acagctaatt
     1201 aagatacttt tcgctgtctt gcctgccgcc agtttgtatt ttttatactg cttgactgca
     1261 aaatgctccg gctctctttc ctccagctca tcaaacatca aatcaacggg atttttaaat
     1321 tcctcgtcat cctccctcgc ttcacttgca tttatcatgt caagcagggt ggtaaaattc
     1381 tgttcttcct ccacgcactc ataccagatg tacccgatca gtgcggtata gtagagcttt
     1441 tcggctttca cccagaaatc ctcgccggat tgctgtccct ctcctttggt gtttaaaata
     1501 attgtgttta caagtttcaa aatgtccttc tcgctccgga tataaacgag aggattgtag
     1561 tgcatggact tcttgaagtt aatggtattc agcactttta cccggtaatt gttctttaag
     1621 agcatttttc cgcactcgac taacacagtg cctttcggat cagtgacaac atagcttgag
     1681 tgcatctgca tcaggttcgg ttttacaaaa aatcttgtct tgccggaacc ggagccgccg
     1741 ataacaagga tatttttatt cctcgcatac ttcggctgtc ttggtctgcc tgacatcatc
     1801 agcctttccg tttctgtaag cagcacattg ttctcaaaga ccggatcgac ataaggctct
     1861 atatcctttg cgtttcccca ccttgcagag ccgtactcca ttccatgccg gaatttcttg
     1921 gcatttttgg ctttgaaata caccacaaga cggagcgcaa cgccgcaccc tgctcctatc
     1981 agcaaatctt ttgggtaaaa actcggtaac gggttagaaa ataagtcctc cattcccgcc
     2041 atgaccgcca tcatctttgc ggaagcgtcc tgccccggcg atacccgcca cagccacgct
     2101 attttgtcgc agaaataccc ggcaagcaca tacggcaggt tcataaggag aagtttcttt
     2161 ttatccacat tccctgtctt tgtcttgagc ttttcgggaa tggattttag gtctttggca
     2221 atgccttcta cgattttact cataatgact gccccctgtc cttctggtgt tcccttgccc
     2281 gctcccggtt tttgtctttc cctaactgct cccggaactc cgccagcttc tcctttacgg
     2341 agatgcggtc atgctttttc tcattaactt ttacaaattc cttaaatgcc tgcgtaatca
     2401 cgtcggcatc cttgcccttg aaaaatacca tgtacttcgg cggtgcaacc gtcttatctt
     2461 ttttcacagc aaaatccacg ttgtattttt ttgccacttt ctcaaaagac ttgatgttgt
     2521 tatccgtcac ctcaatgctc gaagcaccca taccctgacc gaccagatct ttcactgcca
     2581 ttttcccatg tgatgcctgt tttccctgtt tccggtgttc cagatacatc ttcattgcct
     2641 ttttcagcac gtcggtagtc agccgggaag atttaaacac aagggcaatc gttttttgtg
     2701 tcacttcctc ctgcatggtt ttcctccttc ttctttattg ctgtaccccc gtcagggtgg
     2761 gacgtacagc ctgtgaatca gatatttcat aagttctcct ttccacttct ggacaaaaag
     2821 tccaaaagtt ccataaacac aaaaagggca gctacaaacc gctgtttccg gtctataact
     2881 gcccttacgc tgtttcccat attcaattta tctgtaccag atcaccggac actgtttcgt
     2941 ctttttccct actttcctgc gttccagagc aaagaccata tcctctgtac gctcaaaata
     3001 tcctatatcc ttcttccagc tcatgccgca tttacagtgc tgcaagccaa taaactgctg
     3061 tttcatcttc ctgccgcagt tcgggcatac ctttttgctc atgcctttcc gcttcacttt
     3121 tggcttatcc gcatcatctt tcttcttttc gggaatcccg ttctccgcta tccgcacttc
     3181 atagcgtgga agccggtaaa gatacaggct gtatatttca tcaaaggaag tcttttccgc
     3241 tatccccttt accctctggt aaatctgtcc tgcaatcttc tcacattcct ctccttccgg
     3301 cagctttcca tgctccctgt aataatcaca ggtcttttca aacataccgt ccgctatctt
     3361 cgctttctgt ttctgcttta aatctttata tgtcctgtcc gcccttttca gtcgcttcct
     3421 gtttcccaaa cacaccactc ctttatcctg atacgttcta ttgtaacaaa aaacattccg
     3481 gaatggtcaa aaatatctct ttcttagccg aaagcatcct cacaccggga aataaaatat
     3541 ttcttttttt ccagtatttc ctcctgcctg tctttagaaa gcgtctggaa tatctcgtca
     3601 taatccagct ccgcaagcgg tgttcccaac acaggcgtta atacttcatg ctcataccat
     3661 atccgccaca gttcctcaaa cagttccata ctgtccgaaa aagccatcgc agaatcaaat
     3721 ccttctccct cgctgaacca ttgcagacgg acaaacccga accgcccggc atccgccacc
     3781 accacatcgg tcagctcata cagttctgcg aacgcatccg caaccttccg gcatcctgcc
     3841 cgctgttctt ccgtaatata tttttctgcc atagatgctc ctcctaatcc acttctggac
     3901 aaaaagtcca aaagttatct attttatttt aaacagtaaa tcgtgcagag gtcagcatat
     3961 agcataccct ccccacattt tatcgtgtca aacaaaaggc actggaacag tacatcacgc
     4021 actccctcca gactggcaat gccccgttct ttttctgaaa agcctgtgct tggaatatcc
     4081 atatcctccg gcactgcccg ccttgccgag atacagtgcg tataaagtcc gaggatatat
     4141 ttatctgaca taggcaaagc aaatgtttcc tgcccgtcat acgttacccg atacttttcc
     4201 tgttcccctt ccggcagtcc aaaacagcac cgcactgttt ccagataagt atgcccgtca
     4261 aaatccggct ttattttctt cccatacctg cggattgcgg aaaatatgtt attccggtca
     4321 ataaaagaat gggtacgctt aaaagcagcc tttttgcctt tcatatccat gtaaacatta
     4381 ttccccgtcc cttttccggc aaacctgcca taatcgccag tcctcaacag gtaggacagc
     4441 acctctaaca gcttttccct tgatgcaatc tcctgataag gggaatcgct gaaatctatc
     4501 ttcacaaacc ttaacgggca gctccccttt gctatctccc gttccattgc ccggtcaata
     4561 tccctcatgg attccattta tccatctcct tccgctttag actgaaacat tcctttttct
     4621 tcccacccgc cgccatacat atcatgttgt accaactgct ggtaatagtg gttcatggta
     4681 ttgggtgcat tgtagagtgc agtcaccatg tatgccctga tattggttat cttagttgtg
     4741 ttttccttca tgcatccaat gacatactcc aaatgggagc tgttcagctt taggaacttt
     4801 gattttacaa gctcataagg gtaatcttcc ccattgacct ttaccgtcct gcgcttcacg
     4861 cacacaatct cgcagattac ctcatacagt tcctcataca atcccttatc gctccaatca
     4921 ccgtatttca tgtgatgctc atactcaata ttttccttga tgatttccat gtaggcagtg
     4981 gcatcatcca tcacatcaat catatcatca tccagcttac ccggttcttg tttttctgtt
     5041 tctctatccg attgattgat aggattggta taactcaaat tagtataatt agtattgtta
     5101 taattagggt tcgattcccg aacttccgca agttcggttt ccgaacctct tgaagtttga
     5161 tttccgaact cctgcaagtt cggtttccga atttcttgaa gttcgatttc cgaacttctt
     5221 gaagtttgat tatcgaacct cttgaagttc ggtttccgaa cttctgcgga actgtcagca
     5281 ttatccggct tttccggctc tttcccggca tccaatgtcg caaaattctt cacatagata
     5341 atgtccggct tgcccaaccc ctgccttttc ttctcgatca gaccaatccc ttttttgctg
     5401 tcaagctccg caatcacctt tgcacatttt tcccttgcac atcccaaatc ctccattatg
     5461 ttatccagcg tgtaatggat atacaccctg ttttcttcgt caagccagcc attcttgatt
     5521 gacaatgcca gcctgtcaag catcagacca taaaggagct ttgcatcgct ggacaactct
     5581 ttaaaccttg cgtcttttat cagcagtctt ggaactctgt aaaaggaaaa ctgttccgct
     5641 tcgatgccat aataatagtc aaattttatc gtgccatcca cgctgatgca cctcccctct
     5701 attgtttttt cttccattca tccaatagct gaatgatgat gccctctatt tcctcactgc
     5761 tgtaatcctc cgcaaaatat ttgctgattt tatccgcttt cagtgtcacc ttgcgttcct
     5821 tcggcttttc ctccgtcagt atcaggcgca ccattgcaag ggtaagctcc ccggtcttgc
     5881 catattcctt gatttttgcc gactgtacca tgctgatatt gcagcttttt tcctctatga
     5941 cagcctgtac ccattgctgc gcttcctctg tcagaaaaga aatatccacc ccctgtgaaa
     6001 agccgagttt tttactgtct accatagcaa gaagttcttc cgacagccgg gaaagccaga
     6061 tataccgctg aacctttttt gcattttccc cggcagcttc cccgacttca tcaagggtat
     6121 tcttccctga cttttttccc tgatgcttca tcgcttcgta cttcatctta taggctcttg
     6181 ccttttcgct tggtaagatg tcctccctct gaatgttgga atccaccatg ataatcgtcg
     6241 cttcatcatc ggtgtaatta cggacaatca caggcatttc cttctttccg gcaagctctg
     6301 aaccacgttt ccggcggtgt ccggctatga tttcatagcc gccgccctcc ctcggtcttg
     6361 caatgcccgg aacaagcacc ccgtactggc ggatactctc cgttgtttcc tccatcttct
     6421 catcatcttc cacccagaaa gggtggtctt tgaacgtatg caggtctgta agaggtgcgt
     6481 tgataatctg ctctgcggag ctttcctgtt ccgcagaacc gccgaataaa tcctcaaatt
     6541 tatctatcct gacttttgat gcgcttccag ctctcttatt actgcccatc tgcaagcacc
     6601 tcctttgtca gagaatcata agccgccgct actttccctt ttggatcatg cttgtaaatg
     6661 ctgacaccct ccgcagaaat ctccgccgcc cttaccgaaa tggggataat attcgtaaat
     6721 atccttacgc tgcttccata agcgtccttc agcatggagc taatgtcctt tgcataattc
     6781 gtccggctgt ctaccattgt cagcagtatg ccctcaatct ccagtttcgg gttcatcttc
     6841 cgctttacct tgccaaccgt cttaatgagc tgctgtaagc ctttaacggg cagatacgcc
     6901 gcctgtacgg gtatcaaaat gctgtcggca caggcaaggg catttatggt aatcatgccg
     6961 agcgaaggca tacagtctat caggatataa tcgtaattct ccctgactat ctctatgtac
     7021 gaccttaata tcatttcccg gctcataaca ttcacaaggg aaacttccag accggacaat
     7081 tcaatatttc ccggcataag gtctatccct tcctcatggt gcaggatacc ttctgtcggc
     7141 tctacttctt catcattgat taaatccccc ataatagttg caagcgtgac ttccagagta
     7201 tccggttctg tatatcctaa actcgctgtc agactgccct gtgcatccgc atcaatcagc
     7261 agcactttct ttccctgttt tgccagtccg attcctaagt tgcttgtggt ggtggtcttg
     7321 ccgacaccgc ctttttggtt tgcgattgcg attattttac acatgattcc attctccttt
     7381 gctatctact gttcttcttt tacattgctt ttcttaactt ccacataagc ccggtaatat
     7441 ttctttgttc ccttatttga gaataaatcg gaaaactcca tcacctcaat tttgggattt
     7501 ctccgcaaaa tcttaccgaa ccagttaata tcattctttg ttcccattag cctgactttt
     7561 aacatcaatc ctgtcctcca aacatggcgt acagactgtg gttataggtt gcgtattccg
     7621 gatacctgat ctgtatcgcc tgccaaaaat agggtgcata ggcacagcag aataattcct
     7681 ccactgtata aagtttgcac tcgtctacct gttcctccgc atcatcgtaa tcaagaacac
     7741 tcggcgtacc attgcaataa aggttgaacg ccatcctaac tacttttaca ctcccgctgg
     7801 tctgccagcc ttcgtgcagg cattccgttt ttacacagcc tgtcttaaaa tcataaatgc
     7861 ttttaatgtt ccttcttgtg tcattgctga taccaagaca atatacaagt gctttgtggt
     7921 acacgtcctg atacctgacc tctttcaatt tctcatagta gaatttctca tgtccatcac
     7981 tgataaaaat aatctttttc gctttctctg ctcctaacgc tgtactactc attctttttt
     8041 cctcctgttt tgaaattgaa aaggcactcc attattggaa tgccctaata taaaaaatag
     8101 ggacactctc attcaagtat ccctataatc tatcaatata tctgatagtc cactattcac
     8161 tttcattgtc aggatttttt gtgttccccg tatcgaggtc taatgccaca actacggtta
     8221 ctttcttcac aagtatcttt tccttatgat tttcacagat tttattgaaa ctgaaaaatg
     8281 tcacaaagtg cgtaaattca aggatttcta ggtatctttt ctttgtatca acaccacagt
     8341 ctccacatgt gtagaatgag ggaacatatc tacaggttgt gcctcaacac atttaaatcc
     8401 gtgaacattt agatagtcta aatcccttgc taaagtagaa ggattacaag aaacatagac
     8461 aattctttcc ggattcattg aaacaatagt ctctaatacc ttttcgtcac atccctttct
     8521 aggtgggtct acaactacta cattggcagt cttaccctct ctatacatct taggtacaat
     8581 ttcctctgcc tttccaacat aaaattcagc attatgtata ttgtttaatt tagcatttat
     8641 tttagcatct tttatggcat catctataat ttctattcca taaacctttt tagccttttg
     8701 tgccaaaaat aaagatattg tacctatccc acagtaaata tcaaaaacag tatcagtatc
     8761 atttaaattt gcatattcaa gagccttatc atacaatact ttagtttgga cagggtttac
     8821 ttggaaaaat gataatggtg aaatctcaaa cactaagtca cctatataat cgtttatttt
     8881 tccatctcca tatataacta tattttctct tcctagaata gcattcgtat ctttttgatt
     8941 tacatttaca accaaagtct taaatccagg tatattttcc ttaagcactg aagctaattc
     9001 tttaagatat ggaagtttgt ttccatttgc tactaataca accattactt ctttagttgt
     9061 aaaacctatt tttgttacta aatgcctaat caaccccgtg tgagtctttt catcatatat
     9121 acttacctta taggccctta tatatgtttt tattatttta acaattttat catttatctc
     9181 atgttgtatt acgcattttt ctgtcgatat tacatcatga gtcttctttt tatagaagcc
     9241 aataattgga ataccattat tcttttgtat tggaaattgt gctttatttc tatatctata
     9301 tggattatcc attcctatag tgtcatgaac ttctacatcc tctaacttac ctattctcga
     9361 aagtacttgt ttaacttcat ttgttttcat ttcaagttgt ttattataat ctaagtcttg
     9421 tatctgacac cctccacaat ccctaagatt ctcactacac actcttttca ccctgaatgg
     9481 agacttttct attatctcaa caatatctcc tacagcataa tttttcttta ctttattaat
     9541 cctaacttta actttatcct gtattaatcc gccctctaca aaaactgtaa taccattgta
     9601 ctttcctact cctactccgc cttgaccaat gtctactata tctacaatat acatctcgtt
     9661 tttcgaaagc ataaatcacc ctccaatcaa tctattatat ttaaatcttt acaaactttt
     9721 ttctttaaat ttatattaaa atattgctat taattaaact atatttttta ctaagctaca
     9781 atattttatt ttaccaaaaa aaaaggagct tataaagccc cttagtaaat aaatttatta
     9841 tttttcttat aaaactctag ttgaacctct atataccaca cctcttgatg catccacagt
     9901 tacaacttct ccatctttta ctagatttgt tatatcagtt gcagacacaa taactggtat
     9961 atctaaattt atacctacaa tagctgtatg tgatgtcatt ccaccattct cagttactac
    10021 agctcctgct ttttctatat aattgttcat ttcagcatca gtagcagtag aaacaagtat
    10081 gtcgccttca ttaaagtcta cacaagcatt tccattcttt attatacgaa ctttaccttc
    10141 taccgtttga gtacctacac ctataccttg cacgatttct tcgcttatta catgaacctt
    10201 tattaaatta gtagttccac ttactcctac tggtactcca gcagttataa ctactaattc
    10261 cccattatct atataatcag cttgtctagc tgcctcaatt gccttttcta taacttcatc
    10321 tgtatttcct gcaacagaag acttaactgg atatactccc catgtaagag ctaatttatt
    10381 catagtcttt tcattatttg tagtagctat tattggagat tttggtctaa atttagatac
    10441 cattctagca gtatatcctg aagaagtaga tgttattata gctgatgcat ttaaatctac
    10501 tgctgttgta caagttgcat ggcttattgc atctgttaca gtaacattgt tagtaccatt
    10561 ttcctttaat aatctatcat aatctaaagt ctcttctgtt ctttttgcta ttgtagccat
    10621 catttttact gcctctacag gatattttcc agcagcagtt tctccagata acattatcgc
    10681 atctgttcca tcatatatag cattggcaac gtctgtaact tctgctcttg ttggtcttgg
    10741 atttcttatc atagaatcaa gcatttgagt ggcagtaaca actggctttg ctaattcatt
    10801 acattttttt atcatcattt tttgaactat tggcatctct tcagttggta tctcaacacc
    10861 taagtcacct ctagccacca ttataccatc agaaactttt aatatttcat ctaggttctc
    10921 tacaccttct tggttttcta ttttagatat tatttgtata tcagttgcat tattgttctc
    10981 taatacttct cttattgcta gtacatcaga tgcctttctt acaaaagaag cagctatata
    11041 atctattcct tgacttattc caaactctat atcacttata tctttaggag ttattgctgg
    11101 taaatttatc ttaacaccag gtacatttac tcctttatga tttttaacta ttcctgaatt
    11161 ttcaacaaca caaactatat cttctccatt tatttctttt actcttaagc caactaaacc
    11221 atcatctatt agtatagaat ctcctgattt aacgtcctca gcaagacctt tatagcttac
    11281 tgtacacatt tctttagtcc ccataatatc tttcatagtt atagtgaact tttgcccttc
    11341 ttctaaaaat acctctgggt cttcaaagtt acctgttcta atttctggac ctttagtatc
    11401 taataatata gcaactggct tatttaattt ttctctaact ttctttgcca tatcaattct
    11461 ttctttatgt tcttcatgcg aaccgtgaga aaagttaaat ctacacacat ttagaccatt
    11521 ttgcataagt tgagttaaaa cttcctcact ttgtgatgct ggacctagtg tacaaacaat
    11581 ttttgtcttc tttacattat ttaacatatt tgctcctcct gagatattat tccacagatt
    11641 tatttttaat actaaaactt atatagataa tatttttgcc atctcataag cttctttatc
    11701 aaatactttc ttttgagcta aagcttcact tatttctaaa tcaattattt tgttttcttt
    11761 tattcctaca actctagctg attttccatc taataataat tctactgctc ttactccaag
    11821 tctacttgct agtattctat cagatacagt tgggcttcct cctctttgga catgccccaa
    11881 tacagtgact cttaaatctg ctcctgactc ttttttaagt tccttttcta aatcactagc
    11941 acttccgact ccttctgcta aaacgattat actatgtctc ttacctcttt tttgagtagt
    12001 ctttaatctt agagcaactt catctactgt aatttctact tctggtacta ttatagtttc
    12061 cgctcctcct gcaagacctg catataaggc taaatctcca cagtgtcttc ccataacttc
    12121 tactatgtta actctttcat gagatgatga tgtatctctt atcttaccta tagcatctat
    12181 aatagtattc attgcagtat caaatcctat agtataatct gtatatgcta aatcgttatc
    12241 tatagttcct ggtatgccta tagctgggaa tcctaagtca ctaagttttt gggctcctgc
    12301 aaatgaacca tctccaccaa ttacaactaa gcaatcaatt ttatactttt taagaatttt
    12361 tactgctttt aatctacctt cttctgtttt aaattcttca catctggaag attttaatat
    12421 agttcctccc ctgtgtataa tatctccaac agaagataag ttcatttcag ttaaatcttc
    12481 ttctagtaat cccttatatc ctctattgat tccatatact ttgcatccat aatatattgc
    12541 tgatcttaca accgctctaa tcgcagcatt cattcctgga gcatctcctc cacttgttag
    12601 taatcctata gttttcattt tttacctcct tggattttat gtcaattttt tattataatc
    12661 attgttattg tattctaatg gacttttttt gtccctatat cactttttaa tcccatcaag
    12721 actaaaaaaa ttaaatgtcc ttaaatgtcc attttgtgat attatatcac aaaacggaca
    12781 atatttttca tattattata atatatttag atttttatat aaaaaatcaa gcttttactt
    12841 ttatgttatc tttaggaagt aactcttcta agttatttat aaattcatca catatacaag
    12901 tcaatgcccc ggtcatttta tatgctttac gtttaccatt tatattttca tccatagggt
    12961 acaagtatat actgtcatta cctggatatt gtttggctat ttctacaata ttattagttg
    13021 tatcagtatc agacatacta tctattttca aatacaattt tttaccactt tctggcttaa
    13081 tattttctac atttctagtt cttcctgaat tgtagtttct atctgcaaag tcagtatcat
    13141 catttatatc ttttatctct ctagctataa gttttgcatt ttcgccttct tttatactta
    13201 atgttccttt tacatatatt atattatctt cattcaaaat gacattatac ttttgtaata
    13261 attgaggaaa aactattatt tctatagcac catacaaatc ttctaattca ataaatgcca
    13321 taatttcatt tcgttttgtt gttttaatag ttttagttac aatcattcca cccattataa
    13381 catctgtttc attcatttgt aggtatgact cttcttcctc ttttaatgaa tttaattttc
    13441 cattatccat agatgttttt tcttgtagtt ctttttcaaa ttgtgataaa ggatgtccac
    13501 ttacatacat tcccaagact tctttttcaa ggttaagtct ctctctttct tcgtactctt
    13561 gccttttagg caaactgtat atttgttgaa aatcactatc ttcctcacta tctccaaaag
    13621 catcaaataa agaaatttga ccttgaacat ttttctttct atccatagat acactttcta
    13681 ataaactttc ataaccagcc atcagactag ctctattttc acttatatta tcaaaagctc
    13741 cacattttat tagactttct attactctct tatttgtatc tttttggtct aatcttttga
    13801 ctaaatctac taaatctaca aataatccat tagattctct ttcagcgatt atattgttta
    13861 ttatatttac accaacattt tttacagctg ctagaccaaa tcttatattg tcgccttcaa
    13921 ctgaaaactt tgaaaaactt ttgtttatat ctggaggtaa tacatctatt tctagtgctt
    13981 tacattctct tatatactca actaccttat cagtatttcc cattacactg gttatcaatg
    14041 ctgccataaa ttcaactgga taatatgttt ttagataagc tgtctcatat gctaaaaccc
    14101 catatgcagc tgcatgtgat ttattaaatg catatctagc gaagtctatc atgtcatcaa
    14161 atattttatt agctatttcc tcttctacac catttctgat acaccctgca atttctatat
    14221 taccatcttc atcaaattta ccatgaataa aatattgtct ttcttcttcc atcacgtcca
    14281 tctttttctt actcatggct cttctaacta ggtcacttcg tccataacta taaccaccta
    14341 aatctctaac gacctgcata acctgctctt gatataccaa acaaccatat gtaacttcca
    14401 ttataggctt taatttttca tgtagatatg ttacatcttt tgggttgctt ttatttttta
    14461 tatatgcagg tatagaatcc attggacctg gtctaaatag ggatattccc gctacaatat
    14521 cttcaaaatt gtctggtttt agctgtttca taaaacttct catgccagca ctctccaatt
    14581 gaaacacccc tagtgtattt cctgatgaaa gcatttcata tactttcggg tcgtcataat
    14641 ccatctttga aaagtctatt ttttctgtgt agttttttat aactctattt ttttctatta
    14701 aatcaagagt atctcttata actgtaagag ttcttagccc aagaaaatcc atctttaaaa
    14761 gcccaagttc ttcaagtgtt gtcatagtaa actgtgttgt gattgcatct tgatgtttgt
    14821 acaaaggtac atattcatct acgggatttt ttgatataac aactcctgct gcatgagtag
    14881 aagcatgtct tagcattcct tctatctgtt ttgatatatt tattatttct tttgtttccg
    14941 ggtcttggtc atacaattct ttaagattag gatttgtatc tagggcctta tctattgtca
    15001 ttcctaaagc aaatggtatt tccttggcta ccttgtcaac tttattgtag cctatatcca
    15061 atacccttcc aacatctctt attgcagctt ttgcacccat tgtaccaaaa gttattatct
    15121 gggctacatg gtcatcacca tattttctct ttacataatc tataacttct tctcttctct
    15181 cataacaaaa atctatatct atatctggca tggatatacg ttctggattt aaaaaacgct
    15241 caaataatag agagtacttt attgggtcta tgtcagttat tttaagtgta tatgctacta
    15301 tagaaccagc cgcactgcct ctacctggtc ctactataat attattttct ttagaaaaat
    15361 ttataaaatc ccaaacaatt aaaaaatact ctacataacc cattttttca attacatcta
    15421 attcataatt taatctctcc agtatctcat tgctaggatt atcatatctc tcttttaatc
    15481 cattaaaaca caactccctt aaataagttt ctggtgtata tccttctgga acatcatact
    15541 taggaagatg tatagtatta aaatcaaact ccacattaca catatcagct attttcacag
    15601 tattgtcaat agcctctaat gcatatggaa ataattcttc catttcttct cttgatttta
    15661 aataaaactc atcactacca aatctcattc tatttgggtc atttaatgtt tttcccattt
    15721 gaatacacat aagaacatca tgtattttcg aatcttcttt atttacatag tgaacatcat
    15781 tagtagcaac tagtggtata ccagtctctt ttgataattt tactaaacca gagtttactt
    15841 ctttttgctc aggtaaattg tgatcttgaa tctccaaaaa gaaattttct tctccaaata
    15901 tgtctctgta gtcaagagca aattgttttg ctttttcata atttctattc attaaagcac
    15961 gtgctacatc tcctgcaagg catgcagaaa gtgctataat ccctttgtta tgctttttaa
    16021 gttcttccat gtcaactcta ggcttatagt aaaaaccttc tacgtatgaa gttgaaacta
    16081 tttttattaa atttttatat ccttccatat tcttagctaa cagaactaaa tgtccttgat
    16141 atttgtcata gtttgggtct ttatctctca atccacgtgc agctgtatag acttcgcacc
    16201 ctataattgg ctttattcct tcttttatag ctgttttgta gaaatctata acaccaaaca
    16261 tacaaccatg gtcagttata gctattgagc tcatgtttag ttccttagcc ctttttataa
    16321 gttttttcac cctcgaaaac ccatcaagta aactatactc agtatgtaca tgaagatgag
    16381 caaaatcttt gttcattaaa tcacctcctg ctttataatt ttaattttac cacaaatata
    16441 tgtcctaaaa caaaaacaga gacttttatc tcaaaatagg aattaacttc aacgtatacc
    16501 attatatgtt ataaattaat gcttattctg agattgtccc ctcaatttat tgctatgatt
    16561 tttttttcaa atctgttgca atttcttcta tttttctaag tctatgattg actccagatt
    16621 ttcctattgg tggttctaac atctctccaa gttctttgag agtcatatcc tcatactcga
    16681 ttctaatctt agctatctct tgtaaatttt ctggcaaact gctaattcct atagtctctt
    16741 gtatgagctt aatattttct acttgtctta ctgctgcatt tactgtttta gaaaggttag
    16801 ctgtctcaca atttactatc ctgtttacat tatttctcat ttcttttact attttagtat
    16861 tttgaagact taaaagagcg tggtgtcctc ctataatact caacaaatct gatatttgtt
    16921 cactctcttt gatataaaca acgtgattat tttttctagc cacaatttta ctattaaaac
    16981 ctaaagagtt tataagttct tttagagaat ctgcaaactc ctcattatta gttacaaatt
    17041 ccatatgata gttcttttct gggtcgctta tagaacctcc accaagaaaa gctcctctta
    17101 tgaaagctct cttacatcct tcatgcttaa ttaagttctc tgaaattttg tttatagtaa
    17161 aaaatccttc tttatcttca agtataccta acttttttaa taacatctct gaacccattt
    17221 cgcttgttac cattaataca taactgttat ttctctttag catttgattc ttatttactg
    17281 agattgtagt attaatatta aaattctttt ttaataattt aaatacttta cgggctattg
    17341 aatttaactc tgttgttatc tttagattta gcttcttata tccaacaatt tgtatacttc
    17401 cccctgattt aactagagct gacaattcag ctatattaca acattcattc ccagatataa
    17461 ctcttgctag ttcatttttg gtttcagttg aaaaagacat atctatcacc tattaactaa
    17521 tttttcttta accttttttt tatttcttgt aaggcaacct ttattatctc cttttcatca
    17581 tcatacctag ctaagtctac tactctatct aggtggataa atttagcatc aataaagcct
    17641 tcctcttttt gtggaatagt atccatattc tttgcttgca tcaaatacca aaaaactgtt
    17701 ttatgaactg ctctattttc atcccagttt tctttgaatg tatagtgtat ttcacctaaa
    17761 tatttcaata tatctgcttt tactccagtt tcttcactta cttcacgtaa tgctgcctct
    17821 tggttatttt ccccttcttc tacttttccc ttgggtaaca cccaatctcc attgaacttc
    17881 cttagtaaaa gaatcgtatt gccaaacagg actacaccac cagcactaac ctcttctctc
    17941 atcgatgttc actccttaaa actaacataa tgataaggat ttctacacaa ttttttaaaa
    18001 tcctttttta ctaacttttg ttgtaattat gatttagggc taactcaata actatgttag
    18061 atatatactt tgcatcatgt cttatataat tattttttat ttcaattaaa ttcttctcta
    18121 cagtttttat acccatctct tttaatttat ctttttgctt tttatctaac aagacttgct
    18181 ctgctccatc ttgtttatat aagtcaagca tttcttctgg caatatctca ttatttgcga
    18241 ttacataatc tattaaattc tcatcagtgt gttttactat agcattaaca tgctctaata
    18301 cattgtaccc ttctgtctca cctggttgag tcattatatt tgctatatat acttttggag
    18361 ctacagacga tttaatagcg tctacaatcc cctctacaag taaattgggt attatacttg
    18421 tatataaact tccaggaccc ataattataa tgtcagcatc ataaatagat gcaataacat
    18481 cctttaatgg ttttacatct tttggattta aaaaaatttt atcaatagag cttttttgaa
    18541 tttttgactc ttcaggtata ctagattctc catttattat attgccattt tctaatttgg
    18601 caactaaatt tacatcttcc aaagttactg gtaaaactct tcctgttata gcaaaaattt
    18661 cacttaattt atatacagct ttttcaaagt ttccatacaa cccattcata gcagccaaaa
    18721 acaaatttcc aaaactctga ccttttaaaa gcccttctgt aaacctatat tgcataactt
    18781 cattcattgt tggctctata tttgcaagtg ctaataaaca gtttcttatg tctcccggtg
    18841 ggagcattcc taagtcttct ctcaatacac ctgaacctcc accatcatca gcaacagtta
    18901 caattgcagt tatattttgc gtagtgtgtt taaggcctct taaaaatacc gattgaccag
    18961 tacctccacc tatcacaacc acatttggtt ctctattttc aacaatagac ctttgaaata
    19021 gttttacttt ttcatttttt gcttttttat atataaataa cgatacaatt aatgcaatcc
    19081 aacctaaaat tcctacaata ataagtaatt tagccatgtt tgcctccatt atcgcaacat
    19141 agagtctcta tgtttcttta caactctata tcccttatta gataaatcct ccgctataag
    19201 atttgttata gtaactgacc tatgtcttcc acctgtgcat ccaacaccaa ttactagatg
    19261 ttgttttcct tcctctatat attgaggtac taaaaaatga atcatatcta aaagtttcac
    19321 ataaaattct tcactgattt tagaattcat aacataatct ctaacttctt tatcatcacc
    19381 agttttagct cttaactctt caacataata gggatttgga agaaatctta catcaaatac
    19441 taaatctgca tcagcaagta taccatgttt aaatccaaaa gatactacag aaatagttag
    19501 gtttggatta tcttcaccag aagaatatat tttctttatt tcttccttaa ggtctttagg
    19561 tttcatgtta gttgtatcaa ttatacatgt agataactcc tttaaaggtt ccattatctt
    19621 tctttccatt tttatacctt ctggaatctg catatctttt gccaatggat gatttcttct
    19681 tgtcatttta tatctcttta acaatacatc atcattacaa tccaaatata ccatttcata
    19741 ttcataattt tctttttcta aataatttaa gctttcatga agcgcttcaa aaaactttct
    19801 ccctcttata tctatcccta gagcaacttt atcaatactt gaatttggtt gataacataa
    19861 ttctgcaaat ttagttatca aagcaggagg tagattatct acacaataaa atcccatatc
    19921 ctctaaagct ctcattgtct cactttttcc agatcctgaa agacctgtaa ctataacaaa
    19981 tttcattgct aactcctccc ttttatctta tgtttattat attataatgt tttctactaa
    20041 cgatatatcc agattagagt cagatatagt cttcatagct agttcaaaat caccaactct
    20101 ttctggacaa tgtgcatctg agcctattat aaatttattt tctagccctt ttattttatt
    20161 taattgattt acattcaaaa aagaatggct actatttatc tcaagtctag tatttgtctt
    20221 ttttgctgtc tttgctactt cttctatata cacatcgcct ttatctcctg gatgagtaat
    20281 tataaaaata tcattattac ttatcgcatt tattacagct tttgtattat attcttttgc
    20341 tttttcagtt ttaaaaatat agttattaca atgatttaat aagcttctta atgatgttgg
    20401 agtagaacca aagtgatatc cagccataat ataatcaaaa tctctaataa atttatcatc
    20461 catatctata tttcctttat catctaatat gttacactcc atacctaaaa gtatatttat
    20521 atcagtgtac ttatcattta aataatctac ttcttctctc attttgagaa tatctttttt
    20581 ctttacacca tatgcaatat gtttataact atggtcagat attcctattg tttttattcc
    20641 tttagaaatg gctaccttta cattatcctc aatagtccct ttgccatgac tatataatgt
    20701 atgtgtatga taatcagcca gtattttcat ttgttaatcc tctccaagta ttttgacttc
    20761 ttcttccaac ataaccccaa acttggcata tacagcactt tttataacat atattaaatc
    20821 caaaatatct ttagcacttg cttctccttg attgactaca aatccacaat gcttctcaga
    20881 tacttgtgct cctcttaaag taagacctct caatccagtt tcttctatta atttacctgc
    20941 aaaatatcct gttggtctct taaatgtact tcctgcacta gcaaaattta atggctgttt
    21001 agttattctt ctcgtcgcta aatcatccat taaacttttt atttcatcat aatttccttc
    21061 ttgtaactct aattctgctg ataaagctat atatccgttt ttcgatatta tactttttct
    21121 atacccaaat tccatctgtt catttgataa ttcaaatata ttgccttcca tatccatcag
    21181 tcttactgac ttcactatgt ccttcatttc accaccatat gctccagcat tcatggctaa
    21241 tgctcctccc aatgtgccag gtattcctga tgcaaactca aaccctttta attcttgctt
    21301 ttggagagct ttccctaaaa ctgataataa agctcctgac tgagcagtca tcctagtatc
    21361 atttatctca taagaattga aattatcagc taattctatt accactcctc ttattccacc
    21421 atctttaatt aaaatgtttg aaccatttcc aattattaaa tacggaatag attctttttt
    21481 taccaactta agtacatttt ttaattgttc ttcagttcta ggtctaacta atatatctgc
    21541 tggtcctcct accctaaatg aaatatgttt tttcataggt tcatcgactt ttatatcctc
    21601 tttacttaat atatttaata aatttatata tatatcttga ttattcattg tatttcctcc
    21661 caaattatac tgaactttag ctgtcattat tatttaaatt acattagtat atagtattaa
    21721 ctatattcaa taatatatga ttttgcttat catatagatt ttatatttta agcttcttaa
    21781 ttacaaacta tattcaataa atatataata aagtaaaaaa aaaaaaataa caacatataa
    21841 aagaatataa ataatttaaa aaaagcatca atatcactga tatcaatgct ttaaaaggca
    21901 atttaattcg tattatttat ctaactattt ttgacatagc aaagataata aatccctcca
    21961 actactatgg aacctccaac gatatttcca agcgttacaa ataccaaatt agttataaat
    22021 tgaaccatag ttatatttgc tcctaatgcc attcccattg gtataaaaaa catgtttgca
    22081 acactatgtt ggaatccaca taatacaaat agcattatta ctgtccaaca tgaagccaat
    22141 tttgacatta tatcttgaga tgctgtagcc atccatacag ctaaaacgac tagaatatta
    22201 caaagtattg cttttaaaaa cattgatgct atagttgaat taaccttagc ttctgccaca
    22261 gctatagctt ttgtagctgc atctcctgtc aatgtagaag aataaaacac aagtgcaact
    22321 agcaaaattg aacctactaa atttgcaaaa taaaccagtc cccagtttct taacattttt
    22381 cctaatgtta tttttttgtc cataagtgca atagccatta atgtgtttcc agtgaataat
    22441 tctgctcctg ccactactac aagcataaga cctactggaa agaccatagc acttaaaaag
    22501 ctagctaccc ctgggtctac cttgccaaaa gtttgactaa ctatcatact ccccaatgcc
    22561 ccaaaaccta taaatgctcc tccaaataaa cctaatagaa ttgcattttg tgtcgaaata
    22621 tttgcttttt taatgcctgc acttatagtt gcttgtgcag tttccccagg tgtcaagaat
    22681 cctttactca taaatccttc ccccttaaaa attatacttt cccttgtctt tttatggcaa
    22741 taattatata ataacaatat gatatataat aaattttatt aacataaaaa atatactata
    22801 tacttatata tacttgtctc atataattat actatttatt atataacaac tttgttaatt
    22861 tcgaaataat ttatattgaa tttgaaaaat ttaccttttg attatttatt ttacttttta
    22921 attattgagg tattatatat aatagatata tgtttgtgtt attatatata attacttatt
    22981 ttaataaata tttgaaggag ggaattttat gtttgatata tcatttttcg aaatgtcaat
    23041 atatgaaata gcagttacta caatatatat aattaatttc atggttatac taaaccttat
    23101 ctttagagaa aaaagaaaca taaatacaac tttaacatgg cttcttatat tagtattgat
    23161 tcctgctctt ggattcatac tttatatagc ttttggcaga aatatttcaa aaaacaatat
    23221 gtttagattg aaagaaaagg atgataagat aatcaaaagt aatatactag atactcaggt
    23281 taaactccaa tctacatctg aaattgattc agatatacat caacataagg atatgattta
    23341 tgcattggct aattcaaata atgctcatta taccaataat aacgatgtgt ggatttatgc
    23401 tgaatctagt caatttttta acagtcttct tgaagaactt aaaaaagcta aaaaatatat
    23461 aaacatacaa ttttacattt tcaaagatga caaaatcgga actgaaataa tagacattct
    23521 tatagacaaa gctaaagaag gtgttgaagt aagactttta tttgatgcag ttggtggtag
    23581 aacactaaaa aatagtacac tttccagact taaagaaagt ggtgttaaag ttggaagctt
    23641 cttcccatca ttcttgaaaa ttgtaaactt taacttaaac tatagaaatc accgaaaaat
    23701 tgttgtcatt gatggtaagg taggatttgt aggtggatat aatgttggtg atgaatattt
    23761 aggtagaaat ccaaaatttg gtctatggag agatacacat actaagctta ctggtgattg
    23821 cgtaattgac ctaaatatga gattcatcct tgattggaga tatacaacta aagaagattt
    23881 agatttagaa aagtacttta tagaagaaga tacaaattct aatcatcctt ctgaaaatat
    23941 tgggattcag atagtatcaa gtggtccaga tatatcagaa cttgatgaga ttaaatatgg
    24001 ttaccttaaa atgattcaga aagctagaaa gtatatatac atacagagtc cttatttaat
    24061 acttgactca acttttatag atactttaaa aatagcttgt ttatctggtg ttgatgtgag
    24121 agtgatgatt ccttctaaac ctgaccatcc ctttgtatac tgggcatcat attcatatgc
    24181 tggagaactt ttaaagtttg gagctaaaat ctatacttat ggtcaaaatg catttttaca
    24241 tgctaagaca atagttatag atgactctat atgctctata ggaacagcta atatggatat
    24301 cagaagtttt gagcttaatt tcgaagttaa tgcatttatg tactcttcaa aaaaagcatt
    24361 ggaacaaaga attatatttg aaaatgatat tttaaattct aaggaaataa cattagatat
    24421 atataattct aggtctactt atataaaaat caaggaatca atttcaagac tattatcagc
    24481 agttttataa atcttttatt ttataaaaat tttacatttt ggtttatttt ttaaagtttt
    24541 ttatatgtat tatttttttt ttattgaatt tagctcattt tttttatttt ttttaactat
    24601 tctgaattat tttatattat aatagactag tatagttttt atttttaata ggtaactttt
    24661 ttgcattgtt tttataaata aagaaattgt tgtatattat tctttcttta ttgttttggt
    24721 tttgttcacc cacataatgt tggggtcaac tcatggttaa ttattttatg aaaaataata
    24781 actttaaaaa gaaaaggggg atttgttatg tgcgatttta tttcacacaa caagcaatta
    24841 tttgacgaac tagatatatt tattgactct cttgcaacaa aggaaggtgc gttaatacaa
    24901 gttctacatg aagcccaagg tatatttgga tatcttccaa aagaagttca acttcatgtt
    24961 gctagaaaac ttggagtagc tcctgcaaag gtatatgggg ttgttacatt ctattcttat
    25021 tttactacag aacctgtagg taagtataaa atcagtgtct gtctaggaac tgtatgtttt
    25081 gtaaaaggtg ctgacaaaat cttaagtgct tttgaaaaac agcttggcat aaaagttgga
    25141 gaaactacta gtgattttaa attttcttta gaaggtttaa gatgtttggg ggcatgtggt
    25201 ttagctccag ttgttactgt aaatggtaaa gtttatggta aagtgaaacc tgaccaagta
    25261 agcgaaatat tagatactta tagagaatta gaattgaatt gttaagaggg gtgaataaat
    25321 aatgcgtaaa gtaaattcat ttgatgaatt aaaagtttta gctgatgagc tgaaacctaa
    25381 tcttagctta agaaaaaatt attctaagga aaatgtatta agaagagaat tacttgtttg
    25441 ttgtgatact ggatgtacat cttcaaacag tctagaaata gttagtgaat tagaaaatga
    25501 aataaagaaa tcaggaatcc aagataaagt tagtgttcgt ttgacaggtt gttttggttt
    25561 ctgtgctcaa ggtcctattg taaaagttta tcctgataac gttttctacg taaaagttga
    25621 gccatctgat gctgaaaaga tagttcaaag ccacttaatt agaaatacag ttgtcgagga
    25681 attattatat gaggaagaat ctttaagtaa aaaagttgaa gaacaagaag aaatgtcttt
    25741 ctacaaaaaa cagttacgta tagctttaaa aaattgtggt cttatagacc cagatagtat
    25801 agaagaatat attgccaatg atggttattt agctctaggc aaatgtttaa cttctcttac
    25861 tcctcaagaa gttattgcag aggtaaaaac ttctggcctt cgtggtagag gtggtgcagg
    25921 tttccctact ggctctaaat gggaagctgc ttcaaaaaat ccagctggtc caacagataa
    25981 aaagtttgtt gtatgtaatg ctgatgaagg tgacccaggt gcatttatgg atagatctgt
    26041 acttgaaggt gaccctcata gtgtactaga agctatggca atatgtggat acgctatagg
    26101 ttctgataca ggatacatat acataagagc agaatatcca aaatctatag aaagattaaa
    26161 agtagccata gctcaagctg aaaaatacgg tttacttggc gaaaatatct taggcactgg
    26221 atttaacttt aaattagaat taaaatatgg tgcaggtgct ttcgtttgtg gtgaaggtac
    26281 agcgctaatg cattcaattg aaggtagacg tggtgaacct agaatgaaaa cttatagttc
    26341 ttctaagagt ggtctatgga aatctcctac ttgcttaaat aacgttgaga cttttgctaa
    26401 catacctgca attatactta agggtggaga ttggtttgcc aacttaggta ctgaagattc
    26461 tagtggtact aaagtctttg ctcttggtgg aaaagtagaa aatgtaggac ttgttgaagt
    26521 tccaatgggt actactttaa gagatattgt atttgaaatt ggtgggggaa tccctgaagg
    26581 taagaaattt aaggctgttc aaacaggtgg accatctggt ggatgtatac caactgaaca
    26641 tttagacact cctatagact ttggttcatt aagttctatc ggttcaatga tgggctctgg
    26701 tggtatgctt gttcttgatg aatctgactg tatggtagat atagccaagt tcttccttga
    26761 gtttactgtt gaagaatctt gtggtaaatg tacaccttgt cgtataggta ctacaagatt
    26821 attagaaata ttaactaaaa ttacagaagg taatggtact ctacaagatt tagatgacct
    26881 agaaaacctt gctgaaacta tacaaactgc ttcattatgt ggtcttggta aagctgctcc
    26941 aaaccctgtt ttaagtactc ttcaatattt taaagatgag tatatagctc atgttgtaga
    27001 taagaaatgt cctgctggta aatgtcagaa cttactttct tactttataa cagatgactg
    27061 taagggttgt acaaaatgtt ctagagtgtg tcctgctggt tgtataacag gttctgttaa
    27121 ggaacaacat acaatagata cttctaagtg tctaaaatgt ggtgcttgta tagataattg
    27181 tacatttaac gctataatca agaaataact tatttggagg aggaataaca atgagtttag
    27241 ttaatttaac tattaatggc aaacacgttt cagcacctag tggaacttct atcttagatg
    27301 ctgcgaaatt aataaatata aaaatacaca acctttgtca tttacatatg aatgaaatag
    27361 ataagcttga cacttgtgct tcttgtcgtg tttgtatggt tgagacagag agaggattag
    27421 ttccagcttg tggaacagtt ataaaggaag gtatgaaagt tcagactaat agtgctaaag
    27481 cattaaatgc tcgtagaact attgttgaat tattgttatc agaccatcca caagattgtt
    27541 ttgtctgtga aaaaaatgga gattgtgaat tacagactat agctgctgat ttaggagtaa
    27601 gaaaaataag atatcaaggt tctaaatctt ttgcaggtaa agatacttct actaaatctt
    27661 tagttaaaga ccattctaag tgtatattat gtagaagatg cgagactgta tgtaatgaca
    27721 tacaaacagt aggagcatta tctggagtta atcgtggatt taatacttta gttagtacat
    27781 tctttaactc tgatatggtt gaaacagagt gtacattctg tggtcaatgt atatctgtct
    27841 gtccaactgg agcattaaca gaagtagata atgtacctaa actttgggat gttttaaata
    27901 aaaaagaaaa gactatagta gtgcaagttg ctcctgctgt aagagttgct attggtgaag
    27961 agtttggatt agaaccaggg tcaatctcta caggaaaaat ggtagctgct ttaaaagcac
    28021 ttggatttga acatgtattt gatacaaact ttggtgcaga ttttactata atggaagaag
    28081 ctactgaatt tatagaaaga atccaaaaag gtgaaaatct tcctatatta acaagttgtt
    28141 gtcctgcatg ggtaaacttc ttagagcaca attatccaga caagttaaac ttagcatcta
    28201 gctgtaagtc tcctcaaggt atgtttggtt ctatagctaa aaactactat gcacctaaaa
    28261 tattaggaat caatcctgaa gaactttatg ttgtatctgt aatgccttgt gtagctaaaa
    28321 aatatgaagc ttcaagagaa gaattaagtg aatctggaat actagatgtt gacctttcta
    28381 taactactag agagttagct aagatgataa aagaagctgc aatcgattta cctaatcttc
    28441 aagaccaaga ttttgataat cctctaggaa aatctacagg tgctgcatct atatttggag
    28501 caagtggtgg agttttagaa gctgccctac gtacttcata tgagaagata actaataaga
    28561 ctttagataa tgtaaacttc actaatgtta gaggtcttaa aggaattagg gaagcaagta
    28621 tagatgttga tggaactaca gttaatgtgt gtattgtaaa tacacttaaa aacgctagaa
    28681 agattatgga taaggtcaga agtggagaat gtaaatacca tatcatagaa gttatggcat
    28741 gtcctggtgg atgtgttgga ggtgctggtc aaccttatca ccatggtaat actgaaatag
    28801 ttgatagacg tgcaaatgcg ttatatgaaa tagatagaaa taaggctatt cgtaaatctc
    28861 atgagaatcc tgatttacaa gctatttata aagacttctt tggagaacca aatagtgatg
    28921 tagctcataa ataccttcat actcattact ttgataagag ttgtgtctat ggagagtgtc
    28981 cacaagaatg tgcttgtgaa gaagctaagt agtcataaca aagtataaaa tttattctta
    29041 aaaaaggatt gtcttaaaat acttttacgt aatttaagac aatccttatt aatttcacaa
    29101 attaaattat atttctaaat agacttattc tttaattaac ctatctatta attaaagaat
    29161 acctgccatt ctcataagtt gttttgcatt tgtagtttta catcttccat cttttatctt
    29221 atagtcaaaa tgaattttat cgtctacata gtactctgag aaatgatagt ttacaacttc
    29281 aacatctcca ctacctgaaa ggtcacatag ctcaaagtca tgtgttgtca ccatacttat
    29341 aacccagggt tttgataatt tctttactgc ctcacttgct ccaataattc tatcagcaga
    29401 gttagttccc ttaaaaattt catctactag aaccaacatt ggcagttctt ttaaactata
    29461 ttgaatcatt gattttattc taagaatctc agcatagaaa gttgatattc cttgacttac
    29521 atcatcttgt attctcatag aagtaaatat agccatacag gtcgcatcaa aactcttagc
    29581 gcatactgga gcacctgcat atgccagcac taagtttaca ccgatacttc ttaaaaatgt
    29641 tgtctttcca gacatatttg aacctgtgat aatacaagtc tgagaattta attgtatcga
    29701 atttgctatg acactttttt ctgctattaa tgggtggtat acctcttcaa ctttcaatct
    29761 tggagtatct tcatatttta ttactggaaa acatgtattt tcctttacat gagaaacaac
    29821 tgttaaactt attagagctt caaattctcc aatagattca aaccaatctc taatttgatt
    29881 tccatatata cctttccatc gctccaaagc ttctgcacaa tgatagttcc acatcaaaac
    29941 accacaggca attatatata gtatctgatt ataccttagg tttacagcat ttcctattga
    30001 atttaattgt ttaacacctc ttgaaactcc acttccctta gaaagtttat cttgtaattc
    30061 tttcaaatat gcactttcaa acgtctcttt ttctaaaacc tcaaacattt tttcatatac
    30121 ttgtatactt ctactaaatg aaaataatgg agcaagagtt tgcataagtc ttggatatcc
    30181 aaaaccacta aaccctaact ggattataaa aagtaaaaaa acaggtaaaa caggtaaaaa
    30241 tcctaacata caaaatataa aagataagat tgttgcagtt ggtaaacccc aagtaaaaat
    30301 atgcatccat tttggtatat acacattctt attttctcca tactctataa acgattctat
    30361 actactatct gaattgtttt tttgctcttt accaattata ttactgagtg tttgaatatg
    30421 aatagaaaaa tcatcttttg ataaaagttc ttttatagct ctctgtcttt ctaagattac
    30481 attctcatct ggattttcat tccacaaata tttggctaaa aaatttttcc cataagatgt
    30541 attagctaca cagatatatt gatacaatga tgctcttcca aataagtcta aatcttttgc
    30601 ttgcgaattt tcatctttta agtattcttt accatctatt ttaaattcct tccaaccatc
    30661 tccaaatctc ttaatatact tatttaatac ttcgctctta cttttaaaat atgtttcttc
    30721 ttcttttact ttactatgaa taactaagag tgctataaat attattattg ataaaactcc
    30781 aacaaaaata cctactatat ttttattgta aaatccaata gcaaaccctg ctatcactat
    30841 caaaaaagat attaatcttg ctgtacttat gttatttgac tttttactta agagcaattc
    30901 tttttcagta ctactttcta aaagtttact aaaatattct attcccataa aaaattccaa
    30961 ctttcttgtt atataatgaa actcaaatat aaaattaatc tagtattatt ataatctaac
    31021 actgtacttt aaattatcct tatataatat atcttattaa taaacattat atatacaact
    31081 tgattttaat ttataaggtg taggacataa tcctaatcaa tatttaatta aatgatgtgt
    31141 agtccactat tattcagtac tacttagtat cgattaattt tgataatttt ttagtaaatt
    31201 cttgagctgc atcgtatccc attcctcttt gtctaaaatt cattgctgct acttctaata
    31261 tcatagcagt atttcttcca ggtttaacag gtacaactaa tttctctaca ttaacaccaa
    31321 gtatttcttc atattcttta tccagtccca gtctatcata atacttagtt tcatcccaag
    31381 cttctaaatg aactactaaa tctatcattt tagaattttt gattgcccct actccatata
    31441 aacttctaac atctattatt cctattcctc ttatctcaag aaaatgtctt attagttcag
    31501 gtgactgacc cacaagcata ctttcatcta attttcttat ttctacagca tcatctgcaa
    31561 ctaatctatt acccctttga atcagttcta atgctgtttc cgactttcct atactacttt
    31621 caccttttat cagtacacct ataccataaa tatctactag cacaccgtga attgttgtat
    31681 gtggtgctaa cttattatcc aaatagtttg acagtctatt tataagtcta gtggtatttc
    31741 tatttgtgct caaaagtatt cttttatatt ttttagcctt ttcaattaca tctggcttga
    31801 tttccaagtc tctagaaatt attaacgctg gtatttcata tgagaaaaat ctatctagta
    31861 cttcttcccg aatatgacta tccattaatc caaaaaaatt atattctgtc tttccaacta
    31921 tttgtattct ttcatatgca aaataatcaa aatatcctgc aaactgtaat cctggtctat
    31981 ttatatcttg agagtagaca taataatcta catcatcagg catgtatact acttttaact
    32041 tcaactcttt tattatctct cttattgata ctttattgct agtttccatt aattttcttc
    32101 ctttctaaaa aaattataaa cattatctgc aatgctttta ttcattccat ctacttctaa
    32161 aagttcttcc atagtagctt tttttatagc atctacatct ttaaagtgat ttaataatga
    32221 tttctttctt ttttcaccta ttccttgtat atcatctaag atagattttg tcaaagcttt
    32281 atttcttaga cttctatgat atgttattgc ataattatga acttcttctt gtatactagc
    32341 aataaatcta tataaattag ttgttttatc tagttctatt tctttttctt tgcatatcaa
    32401 tcctttagtt ctatgcttat catctttgta cattccccaa agaggtatat ctacatcatt
    32461 gagttctagt acttttttta ctgcactaac ttgtcctttt ccaccatcca acaatatcaa
    32521 gtcaggtaaa tttccatgtt ttaatcttct atctacaatt tcagccatag aatcataatc
    32581 attaggtcca ataactgtct ttattttata tctcctatat tccttcttat cttttttagc
    32641 attcgtatac actaccatag aaccaatcga atctacacct tgtatatttg atatatcata
    32701 agcctctatt cttattggca acttttctag atttaatatt tgctttaatt cttccaatgc
    32761 tccaatactt ttttcatatt ttcttttatt catatcagaa aatttttcaa gatattctac
    32821 agcatttttc ctaaccattt caactaagct tttcttctct cccttttgag gaactcttat
    32881 tgttactttt tgcccctttt tagatgacag ccattcttct aatatagaac tatcttctat
    32941 ctcatcttct ataattaatt ctttaggtat atactcttgt tcattataaa attgttttac
    33001 aaatgaactt aatatagaag ctcttggact atccattacc ccttctaata taaaatgttc
    33061 cctacctaca atcttaccat ttcttataaa aaatacctgg acacaagctt cattatgagc
    33121 tcttgccatt gcaaccacat cttggtttaa gtcacttaca gtagcatcta ttttttgttt
    33181 ctgtatcatc tcttcaaggc tctttatctt atccctatat acagcagcct cttcaaatct
    33241 aaagttcata gaactctcat tcattttttc ctttaaaagt tccatcaatt tttcttcttt
    33301 accagataaa cacattataa tctcttctat catttttcca tactcttctt tagaaacatt
    33361 tcctgtacaa ggtcctaaac atttatttat gtgtagattt aaacaaggtc ttgtcttatt
    33421 ctttattgct ttatctatat ctattttaca gcttcttatt ggatacgtac tacttataag
    33481 ctccaaggta tcattcacag cagttatatt ggtatagggc ccaaaatact ttgccttatc
    33541 tttaagaact cttctaactt ttaagattct tggataatct tcatttgtag ttacttttat
    33601 atatggataa gttttatcat ctctaagcac tacattatac tttggtctgt atctttttat
    33661 taaattacat tcaagtatta atgcctctaa ctctgaatcc gttataatat actcaaactt
    33721 atatatattc ttaaccatag attttacttt agatgtatgg ttttttgaag attgaaaata
    33781 ctgccttacc ctatttttta gagatatggc ttttcccaca tatattatat ggtcgtattt
    33841 gtctttcatt aaatatactc cgggctcaga aggtaatttt tttaaatgct cttgtatatc
    33901 aaacatctcg ccctccaaaa cattaaattt tatactaaaa ttatacccta aaatatgaat
    33961 tttaaaaagt tatacaattt ccagtgcttt agacaagtta aagcccatat tcccttctat
    34021 aattgatttg aaaacaattt taaccatgaa gagtaatatg gactttactt tgtattacta
    34081 tttacaactt atatttgact aatttactta taacaaaaca gtttatcgta tatctgctct
    34141 aaaatttttc acaatttata taacttaaga aaaatatttc tttaagaatt gacctgtata
    34201 agaaccatca actttagata cttcttttgg tgttccagtt gcaactatag ttccaccctt
    34261 atctccgcct tctggtccta agtctattac ataatcacaa gtctttataa catctaaatt
    34321 atgttctatg actataattg tatttcctgt atctgctagt ctttgtaata cttggattag
    34381 cttgtctaca tctgccatat gaagtccagt agtaggttca tctaatatat acaaagtctt
    34441 tcctgttggt cttttactaa gttcagcagc taattttata cgttgtgctt ctcctcctga
    34501 taattgagtt gaaggctgtc ctaatttaat atatgaaagt cctacatcca ttaaagtttc
    34561 taattttctt tttatatttg gtatattttc gaaaaactca acagcttctt ccacattcat
    34621 atctaatata tcagatatag ttttatcttt gtattttact tgcaatgttt ctctattgta
    34681 tctttcacct ttacaaattt cacaaggaac atatacatct ggtaagaaat gcatttctat
    34741 ttttattatt ccatcaccct tacaagcttc acatctacca ccttttacat taaaactaaa
    34801 tctacctttt ttataacctc ttgctttagc ttcattagta gatgcaaaaa tatctcttat
    34861 aaaatcaaat acacctgtat aagtagcagg atttgaacga ggtgttcttc caataggact
    34921 ttggtctata tttataactt tatctatact ttcaattcct tttatctcct tatgcttacc
    34981 agctctttgc ttaagtctat tcactttact tgcaacacct ttgtaaagta tatcgtttat
    35041 taatgtactt tttccagaac ctgaaacacc tgttatgcat gtaaacttac ctaatgggaa
    35101 ctttacatca atatttttca gattattttc tgatgcttta actatttcta taaaacttcc
    35161 atttccttct ctagtagtct caggaagcaa tatttgtttt ttaccactta aatattgacc
    35221 cgttattgag ttctcatttt caattatttc atctaaagta ccctgtgcaa ctatttcacc
    35281 accatgtata cctgcacctg gaccaatgtc tataacataa tcagcttctc tcattgtgtc
    35341 ttcatcatgc tctacaacga ttaaggtatt tcctaaatct gttagatgtc taagagtagt
    35401 tataagccta tcattatctc tttggtgaag ccctatactt ggctcatcaa gtacatataa
    35461 aactccaacc aatgcagaac ctatttgagt agctaatctt atacgttgcg cttctcctcc
    35521 tgataaagtt ccagcttttc ttgataaatt taaataatca agacctacat ctcttaagaa
    35581 catagctctt ccttttatct cttttataat ctcatgagct ataaatctct gtttttctgt
    35641 aagatttata ttttccataa agtcaatcaa ttcatttaca gataagtttg taacttccat
    35701 tatatttttt ccatcaacta aaacagataa aacttccttt ttaagtctca tccctttaca
    35761 ctttggacat ggtctctctg ccatgtattc ttcaatctta tctctcatgt aatctgaatt
    35821 agtttctcta tatcttctct ctaagtttac tattacacct tcaaagtatg atttataatt
    35881 tctagttcct ccaaattttg actcataagt aaactctaca attatattat ctttaccata
    35941 aagtaattcc tccacaaaat catctggtaa atctttaaac ggtgttgtca aagatacatt
    36001 aaaatgctct gctaaacttt ttatcatttt actgtaataa gtgtcatcat taacacctgt
    36061 tgaaccccat gctgccactg caccttgttt tattgataaa tctttgtttg gtactactaa
    36121 ttctgggtca acttctttac tttccccaag accattacaa acatcacaag caccaaaggg
    36181 agcattaaat gaaaacattc ttggagataa ttcttctatg ccaattccat gttctgggca
    36241 tgcaaattta gttgaaaaaa gaatttcttc tccatctatt atttgggcta ttacaagacc
    36301 atcagatagc ttaactgcag tttcaattga atctgctagt cttgattcta ttccatcttt
    36361 aattactatt ctgtccacta caacttctat attatgtttt tgatttttat ttaagattat
    36421 atcatcacta acttcatagt tttcaccatt aactctaact cttacaaatc cttctttttt
    36481 gatattatca aagacttttt tatgtgtacc tttttgtcct ctaacaattg gtgaaagaat
    36541 ttgtaatttc gttctatctg gaaaatctag cattttatca actatttctt gaatagtcat
    36601 ctgacttatt ttttcaccac atgtagggca atacacatct cctactcttg caaataatag
    36661 tctcaaataa tcatatattt ctgttactgt tccaaccgta gaacgtgggt tttttgaggt
    36721 agtcttctgg tcaattgaga tagctggtga taaaccctct atatattcta catttggctt
    36781 ttccatctga cctaaaaatt gtcttgcata agcagataga ctttctacat atcttctctg
    36841 tccttctgca tatattgtat caaatgccaa agaagacttc ccagaccctg acaaacctgt
    36901 aaaaacaata aatttatctc ttggtaattc taaatctata ttttttaaat tatgttcttt
    36961 tgctcctctt attataattt tatcttccat aatgttgttt ttacctttct atttttccaa
    37021 tttttcttct aattgtttca ctttatctct aagttctgct gctctttcaa attgtaagtt
    37081 ttgagcagct tccatcatct ctgattttaa tttatctata ttagctctta tttcgtcttt
    37141 atcatctgta tcagatattc catatacaac ttcttcctct gcaaccttag tagcttctat
    37201 actatctctt atattttttt gtatagtttt aggaatgata ttgtgctctt cattatataa
    37261 attttgtata tctcttcttc tctttgtttc atcaatagca ttttgcattg agtcagttat
    37321 cctgtctgca tacataatta ctcttccatt ttcattccta gctgcacgtc caatagtctg
    37381 tattaaagct gtttcggaac gtaagaaacc ttctttgtct gcatctaaaa ttgctataag
    37441 tgaaacttct ggtatatcca atccttctct aagtaagttt attcctacaa ggacatcaaa
    37501 cttccctaat cttaaatctc ttattatttc tgttctttct aatgtaacta tatctgagtg
    37561 taaatattta acttttatcc ctatttcttt aagatagtta gtcaagtcct cactcatttt
    37621 tttagttaaa gtggttataa gcactctttc atttttttct atagttttag ttatttctcc
    37681 taccaaatca tctatttgat tatttatagg tcttacttct acaattgggt ctaaaaggcc
    37741 agttggtctt attatctgtt ctgctattgt ctctgagtgt tgaatttcat aaggtcctgg
    37801 tgtagcactt acaaacaaca tttgatttat atttccttca aattcttgaa aatttaatgg
    37861 tctattgtca agtgcagaag gtaatctaaa accattctct ataagtgatg tttttctaga
    37921 cctgtctcct gcatacatac ctcttacttg tggtatagtg acatgtgcct catctacaat
    37981 tatcaaataa tcatctggga agaaatccat taaagtatat ggtctttctc cttctgacct
    38041 tcctgtaata tgtctagaat agttctctat cccctgacaa aatcctattt cctttaacat
    38101 ttctatatca tacttagttc tttgttcaat tctttgtgct tctaatagcc tatcattttc
    38161 cttgaaaaat ttaatttgtt cttgaagctc gttttctatt tctacaattg ccttttcaat
    38221 tctttctggc gttgttacat agtgagatgc tgggaatata acaacatgat ttctagtacc
    38281 aacaatcttc cctgttacat aatcaatttc tgttattcta tctacctcat caccaaaaaa
    38341 ttctattctt attgcttttt catcattact agctgggaat atttctagta tatctcctct
    38401 aactctaaag gtacctcgtg taaagtttat gtcatttctt tcgtattgta tctctattaa
    38461 cctttttatt acatcatctc tgtctctttg catacctggt cttatagata acataagttc
    38521 tttatagtct tttgggtcac caagtccata tatacaagat acagatgata ttattatagt
    38581 atctcttctc tctaaaatag atgctgtagc agaatgtcga agtttatcta tttcatcatt
    38641 tatgcttgca tctttttcta tataagtgtc actgtgagct acatatgctt ctggttgata
    38701 ataatcatag taacttacaa agtattcaac tgcattgtct gggaaaaatt ctttaaactc
    38761 actgtaaagt tgtgctgcta gagttttatt atgagccatt attagggtag gtttcttaac
    38821 ttgttgaatg atatttgcca ttgtgaatgt ttttcctgaa cccgttacac ctaataatgt
    38881 cgaaaatttc tcatttctat ttatagaatc cactattgat ttaatagctt ctggttggtc
    38941 acctgtaggt ttgaagtctg attttatttt aaaatccata gtatcactcc ttttttcgaa
    39001 cattagttcc tgacatgtat tattatatca tacctttata aaattgttta agttatttta
    39061 aatattttac ccatttaaat tttacttaaa tctaaaacat aaaaaaagac ttctatcttt
    39121 gcaatagaag tctataattc atggaaaata aatactttat tcaacttaca taataaaatc
    39181 aaatgcttct ttttcaactc catctaattt taaattaaac atttttaata tagttgctgc
    39241 atgtgctctc aggtctcctt cttctataac cacaccatct ttaatatttg gtccaaaagc
    39301 tataaatgga ggtctattac ctttagtagg taaatgacca tgtgtcgcaa cagcaaactt
    39361 gtaatctttt atatctgaat cttttataat acttccttcg aaatcatttc caaatgaaat
    39421 tccttcaaga ccttcaatta ccatttcaaa atcaccttca agaccaaggt tagatgcttc
    39481 ctctttggta aaaatattct ctatgaataa ttcttcttta aattcttcaa gcagttctct
    39541 taattctgtt aacctatcta agttatttac tattatttga gctgatattc cagaagaatt
    39601 tacataggca tcaaaatcct taacttctcc attttcaact tttataaatc catttgattt
    39661 aagcaagaca tttggattta taactttatc aactctaaga tgaccatggt ccccaagtat
    39721 tataaaattt gtatctttgt atgtacctgc atcctttgta gcctgaataa tatctcctaa
    39781 ccatttatca ttcattttta atgctttatc tacttcgtca ttaaataagc cataattgtg
    39841 tcgtgtatgg tccaatgtag ctaaatgtat tagcattaaa tctggtttat attcctttat
    39901 tatatctact gaacagttta ctccaaataa atccatgttg ggttctaatt tccaatcgat
    39961 ataatgacaa tgtctattgt aaataccgtc cattataacc ttactggaac ttcgttcaaa
    40021 agtttctctt gggtcatctt ctctactagg agcccatatt tctgcaatat tataatctat
    40081 atttggattt gctcccatta caggccataa tacactagag gtagttagat tattttcttt
    40141 tgctacatct ataatagttt ttgcttttat gtcctttgaa taccagtacc agtctttatt
    40201 ttctttattt gggtcaaatt tttcattatg atatatacca tgttttttag gatatactcc
    40261 tgtaaccata ctagtatgac acggatatgt cagagtggga taaacacaat ttatattttt
    40321 tactatggag caattttcta gtatagattt aaagtttggt agatttttta caaattccaa
    40381 gtctttttca aataaagaat ctactgataa tactataacc tttgtcattt acattacctc
    40441 ttcatttata tattattgaa tacttttaat caacttacaa gtctatataa ttatttattt
    40501 gttttatcta ttactgcttg cattgcagaa gttcctttgc ttactacatc ttttggattt
    40561 gcatttaaat cagtaagccc ctttttaatc tcatccatta gcttatcagt tgcttccttg
    40621 tatccattta acattggaag tgcaacagca tattgtaatt ggtcagttgc aaccttatat
    40681 tgaggttttt ctttatataa tgtttgtaac ttttctgagt ttgttgcatc ttcagttgtt
    40741 ggtaagtatc ctgttgatga actaaactga acgattttat ctgtttgtgt catccattct
    40801 ataaattctg cacttgcttc tttttcttta tctgttccac cttcaagcat aactagatta
    40861 gctccacctg taggagttgc gtatttttga ttttttggta agaatgctgt tgatatttca
    40921 aacttacctt ctgtttgttg cataagtcct gctaaatctg ctgttgatgt aaatatcata
    40981 cctactttac catttacaaa atcttgtttt gctacgtccc aggcattata atcttctcca
    41041 ggaggcattt tcattattcc agctttcatc atatcttgcc agaacttaac tggtgcttgt
    41101 cctgcctcat tattaaatgc tactttttta ccattagtta tttctcctcc actttgcatt
    41161 accatagctt catagaacca aatatctatt ggcgtttcaa aaccataagt atcttctgat
    41221 ttatttgtca ttttactagc ataatcctta agctcttccc atgattttgg acctgaaggg
    41281 tcaagacctg ctttagttgc catatcttta tttatgtata atattggtgt acttctatta
    41341 aatggcatac caacaaactt atcctcataa tatgaatttg ttaaaagacc agaaaagaat
    41401 ctttcttgat atgttttatc aaaatattta ctcatatcta ctaaagcacc tgctgatgcg
    41461 aatgtacctg tttgagttat ttctaataat gttacatctg gttggtcttt agatgttaag
    41521 gctgcctgta gttttgttgc attttcatag taatctttct gttttaacat atttacttgt
    41581 acatccttat gttcactatt aaattggtca accatttttt gagcagtttc tccattagtt
    41641 ccacctaaag gagcccagaa atctatcttc gtaatattgc tatcagtctt ttctccttta
    41701 gatgcatttg catcattaga atttgaacac ccaactaaag aacctaataa taatgttatt
    41761 gctaatcctg ttgctaattt tcttttaagc ttcattttca tcctccaaat ttagtcttta
    41821 attttttatt ttattcctga atacataaaa gcttctttta cttttttatt cgcaaatata
    41881 taaacaagaa ttattggtaa aattagaatt atatttcctg ccattattac attccatgca
    41941 gtaattcctt ctgaagattt aaggagcgca actcctattg gtaaagttct tattgcatct
    42001 gtatttgtca ttactaaggg ccagaaataa ttattccaat ggtatataaa attaaataat
    42061 ataaatgtta ttactgctgg ttttgccata ggaaccatta ttctaaacat tatttttaag
    42121 tcagaagcat tatctagttt agctgcttca ataatttcat ctgaaatctg cataaaattc
    42181 tgtctaagca gaaatatccc aaatgaagat gtcataaatg gaattataag tggaacataa
    42241 gtatttataa atccaaactt actcatcatc atatagactg gtagaaaagt tacttgtggt
    42301 ggaatcataa gtcctacaag caaaagccca aatagcattt tttcaccttt aaatttaatc
    42361 ttagaaaatg catatgctgc tggaaccata actaaaaatt gtacaattaa aacacttcct
    42421 gttacaaata cactgtttag caaatatcta aaaaatggac ctgaatgcca tgctgtacta
    42481 taattttcta acactatatc atttggtata atagtgggcg gtaattgcat catttcttgt
    42541 ggatttttaa aggatgtaga tagcatccat ataaaaggga atataaatat tgcagataaa
    42601 agtaatagaa ttaatatttc tattgatttt gatgctattt tttttatatc aactttgtct
    42661 tttttgatag gttgtataat atccattgtc tcctcctttt ggataaacct tataatatct
    42721 actttttctt tattgataat gaactttctt tgataagagt ctaaagttag catatgtagc
    42781 aatcataact atagctaaca aaaacatact cgctgcactc gcttgtccta tgtcatagta
    42841 tataaatcca gactcatata tataataaga taacatgtta gttgaaccca ctggcccacc
    42901 ttgtgtcatt atacttatct catcaaatac ttgaaaagat gcagttgttg ttgttatcat
    42961 aagaaaaaat attgttggtg ataatagcgg caatgtcact ttaaagaaat tcgttatttt
    43021 gtttgcatta tctaatttag atgcttcata tatatagttt ggtatggatt taagacctga
    43081 taacactatt aagatattgt atccaagagt cttccatatt cctattagaa ttagtgacat
    43141 taaagctgaa ctttcacttg aaagccactt tgatgttggt aaatgtaatg tcgatagtat
    43201 ccagtttaaa aagccatatt gtggctccat aatccaaagc cacaatacag ctacagatac
    43261 tagtgaaatt acatgtggtg taaagattat actttgcgtt aaattgtgta ttatagaatt
    43321 tttatttagc caaacagcaa gtactatggc tagtgatata gatatagtca ccataaaaaa
    43381 agtataaatt gcagtgttcg ttatagtttg tataaactct ggattcttta aaagttctgt
    43441 ataattgttt aagcctacat tttcaaaggt tgaactaaga agactaccag atttgaagct
    43501 tagagatatc gtcttaatta ttggatagac tataaacaat aaagttccta taatagcagg
    43561 tgttatatat aaatatgctt tattaaattg ctttttcata aatatctcct ttaattttag
    43621 aatacatact tttacatact tttacatctt ctattctttc tccattttta tcaaaataat
    43681 ataaatcttt ttctaataca cttattctta aagttcttcc aatatcaaat atatcatttt
    43741 ccgttttgac tcttatctct ctattaagaa cagataaaca atatatagtt tcatttccca
    43801 acacttcttt agtcacaact tttccaaata ggctaaatac atcatcattt ttcccatcta
    43861 tgtttatact ctctagtgtt gctttttctg gcctgaatcc aaatttaata tcatttttta
    43921 tatctagtat gttcatacaa ggactcccta taaattgagc tacaaataaa tttttaggat
    43981 tttgatatat cttctttggg gaacctattt gcattatctt tcctttgttc attataacta
    44041 tcttatctgc cattgacatt gcctcaacct ggtcatgagt tacataaaca aatgtagact
    44101 ttagtttttg atgtaattgt attaattctg ttctcatttg atttcttaat ttagcatcta
    44161 aatttgacaa tggttcatcc attaaaaata cctttggatt tttaaccata gctctagcaa
    44221 gtgccactct ttgtctttga cctccagata agttgcctgg tttcacattt aaatattctc
    44281 tcaatcctac tacatcaata acttctgtta taagtttttc tcttttttct ttttctactt
    44341 ttttgttttt aagaccaaat tctatatttt ctctaacagt catatgtgga tataatgcat
    44401 aattttgaaa taccatagct atatcccttt tactagcatc cgtttttgta acatcatttt
    44461 cttcaatctt caacctacct gaagttatat cttcaagacc tgcaatcatt cttaacgtag
    44521 tagatttacc acatccactt gggcctacca atactgtaaa agaaccatct tctatagtaa
    44581 gatttaaatt ttctataact gtattttttt tattataaga ttttgttaca ttttctagtc
    44641 ttatatctgc catttttatc ctcccaaaat atttaattta attctacgat ttacttatag
    44701 attaataata ctcttaattt gtaaaggata tattaagaca aagtgaatat atggtaaact
    44761 tattaaaata aaggttaaat tataaacatt ttttgttaaa tatactgagg ttaagatgat
    44821 atacagctta tgttagctat aattttctat atttttcata ttcatggttt gctatcacaa
    44881 tgtaatttta atttatgaag agtcatataa aactatttat tttttatata atttgatttg
    44941 aaagtaaaaa agacctctat gggggataga ggtctttaag tgggggagat tgagtaattt
    45001 atttttgcta tattaagttt tacaattata ttatgtccca aatttacaag gtttaaacat
    45061 aaaaaataaa acttttttaa tttttataaa tttaccc
//
LOCUS       DAMJXI010000028        44187 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.029, whole genome shotgun sequence.
ACCESSION   DAMJXI010000028 DAMJXI010000000
VERSION     DAMJXI010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 44187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44187
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.029"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            182..1261
                     /locus_tag="PC465_001986"
     CDS             182..1261
                     /locus_tag="PC465_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2649281.1"
                     /translation="MSRVKNVVELLETKGVDALYLTKKTNVNYISGFPDEEAYAVICK
                     DGNFLVTDSRYMELAEKVCKDFEIINWHNFDRSVAKAVKSVCDKVGIKKLGFERTNIV
                     FDKYEELKNLIEKDNGELIPTENIVETLRYVKDKDEIKNTRKACEIADKALEELIPHI
                     KAGVSEIELATKLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLID
                     YGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRK
                     VVKKYEDYYYQGIGHGVGRDVHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIE
                     DTVLITKNGPERLTKFPKDLMILDK"
     gene            1374..1973
                     /locus_tag="PC465_001987"
     CDS             1374..1973
                     /locus_tag="PC465_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649282.1"
                     /translation="MYKKHKFIKNIKKAWYKIKLIDRCLIIVMAILMFQSIYNLFVNE
                     VNSQDTTTIDVVVRTTSAAIFGYFLSANFIKRPLRKYTNTDVSSNLFIDNNLSPKGQE
                     SNQNNIMNVKNTIGFTSEADNYEKKIPINNNEGFEEGETSELQIIIATVICIVALTVL
                     FVVRNFTTTTSASLGTISQMRDFVSGCVGFLLGCPSKPD"
     gene            complement(2160..3032)
                     /locus_tag="PC465_001988"
     CDS             complement(2160..3032)
                     /locus_tag="PC465_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2649283.1"
                     /translation="MNINYLYYFQTVCKYKNMTKAAESIHISQPSITLAIKELEKELG
                     FELFYRIGNKIELTPEGKIFLDKSKHFIKQFEDFQCDALDLGKKRKASLKIGIPTVLG
                     TFLLSKILPRFNVIYPDIELKIFEVPTFVGAKMIEESTLDFCIGIIDSDIYDDIDSKT
                     IYKTELYLVTNPKNELAKHPIISNYMLKNVPFVILSEGSYHYKIITKRLEKAKPNIIL
                     HSNQLSTIRYLLENDLASTILYKEIFQNTENLCSIPLERAITANIGVLWRRNQYISHS
                     MKLFIEYMASIHIN"
     gene            3448..4851
                     /locus_tag="PC465_001989"
     CDS             3448..4851
                     /locus_tag="PC465_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649284.1"
                     /translation="MKGSDLVKFELMDFLMNPFVLMFAAVITGILFGKIKFGKFNFGV
                     SGALFTGLFIGWLAYSLGNLIIAKGETAAGYKAATVMMGNGIISSDFFDFFLIIFVAA
                     VGLLAAKDMKAVLKKYGARFVILGVLITFIGGSMTYAMTLLSSDKGSSAYEVSGVYTG
                     ALTSSPGLAAALETAGKHAEDVSKEFEKASIKDKKEILKVVDPEGKLDVNTTTSLTQE
                     QIDKYIAYAEAGVGIGHAVAYPFGVLIVILGVNFLPKLFRMDLKEERRKYEKEMKEAR
                     DSVSGKTIPEVPFNIITFFLTCLAGYLVGGIHVFMGPLGYFTLGATGGSLIVSLVLGY
                     IGKIGVVNFRMEEKVLNILKQIGLVFFLAIVGLRYGGKVVDSIMTSGMHLALVAIAVG
                     VTAMMIGFLVGKYVFKLNWILLSGAVCGGMTSTPGLGAAVDALDSDDPAAGYGATYPF
                     ALLTKVILVIVLHKLPM"
     gene            4878..6422
                     /locus_tag="PC465_001990"
     CDS             4878..6422
                     /locus_tag="PC465_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HDF2649285.1"
                     /translation="MNNEGAFEELSGRLRNKELCDLIMNADEAAKIIEDGMVIGVSGF
                     TPSGYPKAVPLAVSERAKSGEKIKLTVYSGASLGPEVDGAWSEAGIIERRLPYQTNSI
                     LRNNINKGVVDYIDMHLSHSTQFLNYGTIPKVDVAIVEALAITEEGNIIPTSGIGNSP
                     SFIKSADKVIVEINLAKPMEMEGMADIYITENPPNRKPIEINHPKDRIGTTYIPCGLD
                     KIAGVVITNMQDKTRPLGVVDEASKKISNNIIAFLREEVKAGRLSKNLLPLQSGVGSV
                     ANAVLYGLCESEFENLTCYTEVVQDSMLDLIRMGKVTMASTTSVSPSPEGLIKFEKDI
                     DFFKDKIILRPQEISNNPEIARRIGVIAMNTAIEVDIYGNVNSTHIMGSKMMNGIGGS
                     GDFARNGAITIFSTESIAKNGDISSIVPMVSHVDHTEHDVMVIVTEQGYADLRGLAPR
                     ERAIKIIENCAHPDYKEQLRDYLNRACKSGAKQTPHILDEALSWHSKFMSTGTMKKAE
                     TFKSAL"
     gene            6453..7844
                     /locus_tag="PC465_001991"
     CDS             6453..7844
                     /locus_tag="PC465_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HDF2649286.1"
                     /translation="MEKAVENFEDLSKEYINGYIERARKAQREFECYTQEQVDKIVKI
                     VGKVVYYNAEYLAKLAVEETGMGVYEDKVAKNKSKAKVIYNNLKDKKSVGIIDIDRET
                     GITKVAKPVGVVAAITPCTNPIVTPMSNAMFALKGRNAIIITPHHKAIGCSTKTVEMI
                     NEELEKIGAPENLIQILDQQSRENTRNLISSADVVIATGGMGMVKAAYSSGKPALGVG
                     AGNVQCIIDRDVDIKEAVPKIIAGRIFDNGIICSGEQSVIVAEEMFDKIMDEFKNNKG
                     FIVRDKVQKEAFRNAMFVNKSMNKDAVGQSVHTIAKIAGVEIPEDTKIIVIEADGPGE
                     EDIIAKEKMCPVISAYKYKSFEEGVAIAKANLNVEGKGHSVSIHSNTVKNIEYAGENI
                     EVSRFVINQCCATSAGGSFFNGLAPTNTLGCGSWGNNSISENLDYKHLINISRIAYYM
                     PENEVPTDEELWG"
     gene            8037..9533
                     /gene="abfD"
                     /locus_tag="PC465_001992"
     CDS             8037..9533
                     /gene="abfD"
                     /locus_tag="PC465_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyryl-CoA
                     dehydratase/vinylacetyl-CoA-Delta-isomerase"
                     /protein_id="HDF2649287.1"
                     /translation="MALMTGAQYIESLRKLNTKVYMFGEEVKNWVDHPMIRPSINCVA
                     ATYDLAHDPEYADLMTVTSNITGEKINRFGHLHQSVDDLIKKVKMQRLCGQKTASCFQ
                     RCVGMDAFNAVYSTTFECDKAHGTNYHDNFVKYLTYIQENDLVVDGAMTDPKGDRSLS
                     PSAQPDPDMFLHIVERREDGIIVRGAKAHQTGSINSHEHLIMPTISMTEADKDYAVSF
                     AVPSDAEGVFMIYGRQSCDTRKLEEGADVDLGNKEFGGQEALVVFDNVFVPNDRIFLC
                     GEWDFSGMLVERFAGYHRQSYGGCKVGVGDVIIGAAALAADYNGANKASHIKDKLIEM
                     THLNESLYCCGIACSSEGHKTEAGNYQIDLLLANVCKQNVTRFPYEIVRLAEDIAGGL
                     MVTMPSEKDFKSDLKVGTSGMTIGEVCNKYFKASSVASTEERMRILRFLENICLGSSA
                     VGYRTESMHGAGSPQAQRIMISRQGNINQKKELAKKIAGIKKEEALNL"
     gene            9668..9943
                     /locus_tag="PC465_001993"
     CDS             9668..9943
                     /locus_tag="PC465_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649288.1"
                     /translation="MTCGVRFCGGCNPRYERGKALTIIKEHFNGRVDFSIAQENVEYD
                     LLLIIGGCATLCASYQQYKVKNECVKMWDFSHIERVINVIESAICET"
     gene            9967..11274
                     /locus_tag="PC465_001994"
     CDS             9967..11274
                     /locus_tag="PC465_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HDF2649289.1"
                     /translation="MSWQELYQSKLCSATEAVKQIKNGDTVVFAHCVGEPPALVEAMI
                     ENAEQYKDVEIKHMVSLGSGGYTAKGMEAHFRVNPMFVSGNVRKAIENGDGDFTPAFF
                     HEVPKLLREKRLKCDVVLAQVTPPDEHGYCSLGTSVDYTYEAIKTARTVIVQVNDQFP
                     RTYGEVVHVSEFDYIVEKSQPLFELQPAKIGEVEEAIGKNCASLIEDGSTLQLGIGGI
                     PDAVMLFLTDKKDLGIHSEMISDGTLALYEKGVINGKYKNFDKEKMTVTFLMGTKKLY
                     DFANNNPAVEVKPVDYVNHPAIIMKQHKMVSINSAIQVDLMGQVVAEAMGLRQFSGVG
                     GQVDFIRGVSMGEDGKAIIAMPSITTKKDGTVISKIVSIVDEGAPITTSRNDVDYIVT
                     EYGIAELKGKSLRERARNLINIAHPSVRESLAVEFEKRFKEKY"
     gene            11294..12412
                     /locus_tag="PC465_001995"
     CDS             11294..12412
                     /locus_tag="PC465_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyrate dehydrogenase"
                     /protein_id="HDF2649290.1"
                     /translation="MEALRVVPKIFYFDTFKEFNEEFKIGKNDLVITNEFIYEPYMKP
                     LGIDTNLIFQEKFGTGEPSDEMIDSMTKEMKKYNFDRIIAFGGGTIVDICKILALDVP
                     EKSIDLFEGEVSPKKVKELVVVPTTCGTGSEVTNVAIAELKSKHTKKGLAVEETYADY
                     AVLIPETVKGLPYKFFVTSSVDALIHAIESYLSPKASPFTEMYSLQAIKMIMDGYKKI
                     VDKGEEERFNHLRDFVLASNYAGIAFGNAGCAAVHALSYSIGGAFHVAHGEANYQFFT
                     EVFKMYSRKKPNGKIIKCTKILADALECDPNCDVYGELEKFLNKLIAKKALREYGMVE
                     SQIDEFTDSTIANQQRLLANNYVELSREEIREIFANLY"
     gene            12699..13619
                     /locus_tag="PC465_001996"
     CDS             12699..13619
                     /locus_tag="PC465_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HDF2649291.1"
                     /translation="MYKSENFSKKSVLINSFLSKFLKIIGWGLVSLFTLSALVLSTIS
                     IIIGWAVILPIQVCAVFLLIGGVCIFKGKRLGDQISRYKKYCTIINNRNIIPVELIAE
                     NTSKSLNFIIKDVQKMIDKNYFINTYIDKRNNQIVLTNEDFIPPRYEDVAYEVKEEEK
                     TDESNEVDTIINKGMNYLTQIKEANKNIKSESMGNKIVQVEDVTSKIFDVVKHDPSKL
                     TQIQKFMDYYLPTTLKLLNSYHTLEEQGIDRENITTTMESIENTMNTIVVAFENQLDY
                     LFEDEAIDISTDITVLENMLVQEGLTSGKF"
     gene            13734..14891
                     /locus_tag="PC465_001997"
     CDS             13734..14891
                     /locus_tag="PC465_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HDF2649292.1"
                     /translation="MNNLDDIPVMPTLTLDPFGEESNTNDIDNSDLLMKKDEKDPEEE
                     KLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVASFSETALKSVKTRDLGEVGDM
                     LTNLVTDLKAFSADEKEQSGFLGIFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQV
                     KILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARLSGSTEDA
                     QSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPL
                     WKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDID
                     TIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLEFTVK"
     gene            complement(14976..16475)
                     /locus_tag="PC465_001998"
     CDS             complement(14976..16475)
                     /locus_tag="PC465_001998"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HDF2649293.1"
                     /translation="MAFYFDTPSHTFSEYLLVPGFSSTDCIPANVSLKTPVTKFKKGE
                     EADIYMNIPLTSAIMQSVSDDKMAIALAKEGGISFIYGSQTIENEAAMVARVKSHKAG
                     FVVSDSNIKPDNTLKDILDLKEKTGHSTVAVTEDGTSTGKLLGIVASRDYRISRMDLD
                     TKVSEFMTPMSSIVYANKDVTLKEANNIIWDHKLNSLPVLDDNGNLMYMVFRKDYSSH
                     KENPLELLDSSKRYVVGAGINTRDFAERVPALVEAGADVLCIDSSEGFSEWQKITLDF
                     IREKYGDTVKVGAGNVVDREGFLYLAEAGADFVKVGIGGGSICITREQKGIGRGQATS
                     IIEVAQARDEYFEKTGIYIPICSDGGIVYDHHITLALAMGADFIMLGRYFSRFDESPT
                     NKVNINGSYMKEYWGEGSARARNWQRYDLGGDKKLSFEEGVDSYVPYAGSLKDNVTLS
                     LSKVRSTMCNCGALSIPELQKNAKLTLVSSTSIVEGGAHDVMLKDNRNL"
     gene            17071..18495
                     /locus_tag="PC465_001999"
     CDS             17071..18495
                     /locus_tag="PC465_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HDF2649294.1"
                     /translation="MSSSNQSTIKTSIQRVGKFLSGMVMPNIGAFIAWGLITALFIPT
                     GWMPNEKLSTIGDPMIKYLLPLLIAYTGGKAIAGQRGGVIGAAAAMGVIVGADIPMFI
                     GAMIMGPFAGWVIKKFDKFVDGKIPTGFEMLVNNFSIGIIGMLLAILGFYAIGPAIVA
                     GTALIESGVQFIVSKSLLPLVSVFIEPGKVLFLNNAINHGILGPIGIAEAKEAGKSIM
                     FLLESNPGPGLGVLLAYWMFSRGSVKQSAPGAVIIHFFGGIHEIYFPYILMNPVLILA
                     TMAGGAAGILTFSILGAGLVAAPSPGSIFALMALAPKGGLLPVLAGVAVATVVSFLVA
                     APFVKRASANQSEEDSTSLEEAKAKMSDMKSASKNSEKNIDEKQLEVNEIKKIVFACD
                     AGMGSSAMGASRFKNRIKNLDLNIEITNSSVDNLPDDTQIVVTHNTLVERVAKNNSSV
                     EIVSINNFLNDPNLDTLFKRLESK"
     gene            18530..20659
                     /locus_tag="PC465_002000"
     CDS             18530..20659
                     /locus_tag="PC465_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDF2649295.1"
                     /translation="MKKKKITSRQKKIILMIVENSKKNIPITISEIAGTLELSSRTVL
                     RDMSGIEKWFDENDFNFVKKPGVGLILEENIENQNFIIELLEEEKIEKEYSKEERNLI
                     ILSKLLVSNEPVKSYYFAKILKVSEGVLNNDFALASKWLERFDIELVRKPGLGVYLKG
                     QEKSFREAYVNLIYDSFNEKEILDMVRNISENIQTDKAIEILSENRLLNLMDRCIIRK
                     VEATLTKKLSDLDVNLADSAYIGLVVHISLALQRIKNGENITMDKEFLKELSITEEFK
                     LAKEIVKGMETDFNMDIPVDEVGYITMHIRGAKQRSSSNHKALNLDDIEIMEITNKMI
                     DLAEDEFKISLKNDERLFKDLANHLGPSINRLNMGLEIRNPLLDEIKSKYSYAYDGVE
                     KISRIIKDKLNINSIPESEIGYIAMHFASAIEKNLMMNTNINIVVACPTGIGTSRFLS
                     TKIENKFPNLNILETISAINIDEEYLKEKDVDLIVSTVELNTSLNYICVGPFMSLDDE
                     QIIKEKIKSIAQNKLINLNAKNDTKSKNKVYEQITESMNIGKDILQFLEEIRFEKFES
                     KDLSELIEDSSRIFAKSSEDIISIKESLKERLKISIPYIEESKILLLHCMSERIDIMK
                     LSIIKLENRIVLDSNEEIDNVVFMLLPKNSPSYQRQIMSEISGSLIDNIIFTNKINKF
                     SIEEMALEVKDIVFNFYTNRLKAFIDK"
     gene            20689..21111
                     /locus_tag="PC465_002001"
     CDS             20689..21111
                     /locus_tag="PC465_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2649296.1"
                     /translation="MSKVLNENNIFLGLDSVSKEEAITLAGRKLVENGYVKEEYIPAM
                     LEREKVMTTYMGMGVAIPHGVNEAKKEILSSGIVILQFPNGIDFDGEKAYLLIGIAGV
                     GDEHLEILSNIAVVLDDDLTERLKNSNDKQAFMEAFAN"
     gene            21130..22281
                     /locus_tag="PC465_002002"
     CDS             21130..22281
                     /locus_tag="PC465_002002"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF2649297.1"
                     /translation="MKKAIQFGAGNIGRGFIGGLLVKSGYHVVFADVNEDILNSINKD
                     KKYTIHIRDVECIDEVIDNISAVSSIKEEIIDEIVQAEIITTAVGPLVLTKIASTIAK
                     GIKARKEKGLTSNLNIIACENAIYASSSLKEEVLKYLNKEEVEYLEMYVGFPNCSVDR
                     IVPPGKNENPLDVTVENFYEWNVEKQGFKGEIPTIVGMNLADNLMAYIERKLFTLNTG
                     HAITAYIGYLKGYKTIEESIKDKFICDIVKSAMVESGEGLIKKYNFDSEVHYKYIDKI
                     LNRFKNPYLNDDVLRVGREPLRKLSDKDRLIKPLMTAKSYGLSVDNLILGIGAALHYN
                     NSEDTQSVELQELIKSIGVKKAVAKIANISNDEELLNNIEKSYIFMKNL"
     regulatory      22387..22488
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            22671..23243
                     /locus_tag="PC465_002003"
     CDS             22671..23243
                     /locus_tag="PC465_002003"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HDF2649298.1"
                     /translation="MKALQEKILREGSVSGNDILKVDSFLNHQIDVAFLNEIGREFKE
                     RFKGEKVDKIFTIEASGIAIASIVSQYFDNAPVVFAKKSESKNLDKDVYETNVYSFTK
                     AREYSVKVSKKYINKGENILIVDDFLANGRAALGLKDLIEQAEANLVGVGIVIEKGFQ
                     AGGALLKANDVRLESLAVVESIDNGTVKFR"
     gene            23307..23957
                     /gene="fsa"
                     /locus_tag="PC465_002004"
     CDS             23307..23957
                     /gene="fsa"
                     /locus_tag="PC465_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDF2649299.1"
                     /translation="MRFFIDTANIEEIKEANDLGVICGVTTNPSLIAKEGRDFIEVVK
                     EISEIVDGPISAEVISLEHKGMIEEAEKLSKIHKNIVIKIPMTAEGLKAVKVLSSKGI
                     KTNVTLIFSAGQALLAARAGATYVSPFVGRLDDISQNGLDLIEEIVDIFSVNSIEAQI
                     IVASVRNPIHVLQAARMGADIATVPLKVINQMIKHPLTDKGIDSFMKDWEGASLKL"
     gene            24109..27033
                     /locus_tag="PC465_002005"
     CDS             24109..27033
                     /locus_tag="PC465_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2649300.1"
                     /translation="MDKILREIQREDKKNPYTDQELAEMLNVARSEVISVRKKNNILD
                     SRERRKKILIKDISKIVSENPQMSERKITEILIENGYNISRSAVSKLLKEENLNQSKI
                     GIKDKDPASSGKYVKVSKVVEEDGFEELIGIKGSLKEKVNLAKSAIMYPPNGLHTIIY
                     GETGVGKSELATCMYKYAIKNNIKEENSPFIVFNCADYAENPNLLIAQLFGVVKGAYT
                     GADANREGLVEQANNGILFLDEIHRLPAAGQEILFSLIDRGEFRRLGESSSNRKANVL
                     IISATTENPDSNLLQTFRRRIPMVINLPNMSERPKSERYEIIIKFFEREAKRVNKNFI
                     ITKEVMCALMNYKCTGNIGQLKSDIQVTCARAFSKSIFSSDKVIIDLDSLRDYIKSGY
                     YDCNCKNEKYSEFSVEDIYIDISELVSGKNRILSDNEISEIYNYAEKELKVLESKCFS
                     EEELKNAFIEKLDKKFNAIKNNKNLSDRRSRIDWGGQLKESTLEIMDKVIVFIKEQFK
                     HVNQGLYLALAIHIEHAIGRIKDGKTIINPSLDKIKASMPMEYELSRYIMGIVEDLTQ
                     VTFPEDELGYLAYYINKFCYNEESIKDKVKVVIVTHGKVGIEMSKVVNHILGIECTLG
                     IEIALTDSPSEGIEHVLEELQKIEARKGILVLIDMGSLVILGDEVEKRLGIRCKTVNR
                     VDTLLAMEAGKLATIEGKSLDGIIADLKKNKNYAMINTNKFSYRKNEYGKKNVIITLC
                     LSGVGTALNLKEHIEKQIKEYDTLIEVKPVAFLNNNLEEELNDIESEYNIIAICGTID
                     IDYKNVPFISYNEVLGKNGINKVLEHLNSKQPALNIENQLNNLIHEDLILYNFEGISK
                     EYIIDTLVSKLEEGGYVDSKYILSVYKREAMGSVVMASKVAVPHGLPENVIKPAIAIA
                     RLNKPIVWDNKFMVDLVVLLALKENNKKEIRSLFSKINDQHTLEVLLNTEDKNEIKEL
                     LS"
     gene            27611..28069
                     /locus_tag="PC465_002006"
     CDS             27611..28069
                     /locus_tag="PC465_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2649301.1"
                     /translation="MEFINFVSDKVIDLKMDCKTKEDFFEEIHNKVFDLGFVKEEFGE
                     KILARENVFPTGLNLGDYGVAIPHTDAEYIKEQFISVCTFNEPVVFSSMEDQDEKVPV
                     NLAFVLGLNQPHSQLSVLTELMGIMQNKELVDKLMSSTDKEEVLKTLKSL"
     gene            28130..28405
                     /locus_tag="PC465_002007"
     CDS             28130..28405
                     /locus_tag="PC465_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2649302.1"
                     /translation="MKKILVACGAGIATSTVVCDKVERLVKENNIQAEVIQCKIAECA
                     TKQEGADLIVSTTILPTTYNIPAIKATAYITGVNTAALDKKILDALK"
     gene            28464..29738
                     /locus_tag="PC465_002008"
     CDS             28464..29738
                     /locus_tag="PC465_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012951111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDF2649303.1"
                     /translation="MDKLLAVVQYILNMGPTVILPITIVVLGMIFRIKFTKALKSGLT
                     IGIGFVGINLVVNLLTSTLGPAAQGMVERFGLNLTVIDVGWPTTASATWASPVAPILI
                     PVCLLVNLLLLYFNKTKILNVDIWNYWHFIVAGAVGYIVTGSYVWAIFCAILMELLVL
                     FIAEKTAKNVQEFYDLEGIALPTGSTASFAPLGYLVGKFVEKIPGINKIQADPDSIQK
                     RFGIFGEPMMMGIILGIILGALAGYDVAGIFNVGISMGAVMLLMPRMVRILMEGLIPI
                     SESIRDFLQAKYGDRELYIGLDAAVATGHPAVISTALILVPITLFLAVILPGNKVLPF
                     GDLATIPFYMAFIVCFRKGNIVQSVITGTIVIAISLYMATNFADVHTQLLQQANMMPE
                     GTTMVTSIDTGGNLLKWGILKLSQLVSSFGIF"
     gene            29868..30920
                     /locus_tag="PC465_002009"
     CDS             29868..30920
                     /locus_tag="PC465_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF2649304.1"
                     /translation="MKAAVLHGTNDMRFEDIEIKPCESDEVKIKVMAAGICGSDPPRV
                     LKHWKYPVPAIPGHEFSGVIAEVGKDVKNVKVGDRVVAIPFIPCNECEYCKRGLFSLC
                     DNHGMLGAKSFGAFAEYVNIKATNVLPIGDMNFEDAAMIEPLAVAMHGVLNIGVQVGD
                     TVAVMGSGTMGQLVIQGLKIAGAGTIIAVDISDNKLRESKELGADIIINAKDINPVEK
                     IKELTGGKGVDIALECAGSKITQEQCLLITKKKSKIGFLGIAYSDITLSEEAFENIFR
                     KELELKGFWNSYSAPFPGQEWTKGINLVNEGKIKLKEMVSHRFSLEDTYKAFEMIRDR
                     KEEFNKILILPQGVEK"
     gene            30920..31951
                     /locus_tag="PC465_002010"
     CDS             30920..31951
                     /locus_tag="PC465_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HDF2649305.1"
                     /translation="MKAVVKTKPGYDNVEVLEVEEPKATGDKVKIKVEYSGICGSDIH
                     SFKGEYANIKAPVTLGHEFSGIVVEVGEDVKNIKVGDRVTSETTFATCEKCIYCETKD
                     YNLCPTRKGIGTQVNGSFAEYVLSREESIHVLPENVSLLSAALTEPLACCVHAALEKT
                     TIESSDTVLIIGPGPIGLLLAQVVKSQGATVIMSGVTKDKERLEIAKNLGVDRTVNVM
                     KESLADVVNEMTDGNGVNKGFDCSGFMPAVNEALRLLRKKGTFVQVGIFAKKLNEMDQ
                     EAIIQRELQYIGSRSQKPSSWITALDLMANGKVNTEALVTRTVGLDEFKEGITALMNG
                     EEIKVAVKS"
     gene            32043..32855
                     /locus_tag="PC465_002011"
     CDS             32043..32855
                     /locus_tag="PC465_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDF2649306.1"
                     /translation="MSTLRDHSNNIRKNIIKMVAEAKSGHPGGSLSIADMLTVLYFDK
                     MNVCAENPKMADRDRFVLSKGHAAPALYATLAEKGFFPEEELITLRKFGSKLQGHPDM
                     KKVAGIDMSTGSLGQGLSAANGMALAGKLDNKDYTVYTILGDGEIQEGQIWEAAMTAS
                     HYKLDNLIAFVDLNGLQIDGSNEEVMNVNPVDDKFKSFGWNVIVINGHSFEEIGNAVD
                     EAKKVTGKPTVIIAKTVKGKGVSFMENNAAWHGTAPNAEQAEQALKDLEGGL"
     gene            32858..33778
                     /locus_tag="PC465_002012"
     CDS             32858..33778
                     /locus_tag="PC465_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HDF2649307.1"
                     /translation="MGIATREAYGQVLKELAENKDIVVLDADLGKATKSISFKEVAPD
                     RFFDMGIAEGDMIGTAAGLATCGKIPFASTFAIFAAGRGYEQIRNSVAYPNLNVKIAA
                     THAGVTVGEDGGSHQAIEDISLMRGIPNMVVLNPADALEARQAILASIDYNGPVYIRL
                     GRAATPDVNSENYKFEIGKGTVLREGSDITVIATGIMVAKALEAAEELAKEGINVEVV
                     NISTIKPLDEALIKETAKKTGKVVTAEEHSIIGGLGSAVCEALAETKDVVVRRIGVKD
                     VFGQSGTPADLLKHYGLTTEDIVKNIKELL"
     gene            33953..34399
                     /gene="rpiB"
                     /locus_tag="PC465_002013"
     CDS             33953..34399
                     /gene="rpiB"
                     /locus_tag="PC465_002013"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HDF2649308.1"
                     /translation="MKISIGCDHGGYELKEYIKENLINKGIEVEDVGTNSKESVDFPI
                     YAKKVSQNVQSKKSDLGILCCGTGIGMSIAANKFKGIRAAVVSDCFSAKATREHNNTN
                     VLCLGERVIGKGLAMRIVEEWLNSSYNGERHARRLQMIDDIEKENL"
     gene            34429..35094
                     /locus_tag="PC465_002014"
     CDS             34429..35094
                     /locus_tag="PC465_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDF2649309.1"
                     /translation="MSIICASIMCADQMKLKEELEALEEAGVKLLHCDVMDGIFVKNL
                     AMGPELLKSISENTTIPLDIHLATETPDKYIDMMSYIKPKYISFHVESSTNVKADIQK
                     LRNYGIGPVLAISPQTSVDKIEEYISLVEGILVMTVNPGFAGQKFNLSVLDKLDKLTE
                     ILKDYDNPPFIEVDGNINKDTIKLMNGKKVDIYVVGTSALFNDKPPISYKDKIEELKE
                     SIK"
     gene            35204..36706
                     /locus_tag="PC465_002015"
     CDS             35204..36706
                     /locus_tag="PC465_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HDF2649310.1"
                     /translation="MGDLYKLQNGTDIRGIAYENDSKEVNLTVEEVKKIAKAFHIWLK
                     EKTKKDKVTVAIGTDSRITGSQFRSTVIETLTNDDCNVIDCEIATTPAMFMTTIMDGY
                     NSDGAIMITASHLPYYYNGLKFFTESGGLEKTDIKEMLDIAVKNDSVDYEEVNKKGEV
                     IVKNLIEDYSNLLIDKIRKGVNSSKNYEKPFSGLKILVDAGNGAGGFFAEKVLHILGA
                     DTTGSQFLNPDGMFPNHIPNPENKEAMESICKAVLDNKSDLGIIFDTDVDRAAIVGKN
                     GKPINKNALIAVISSIVLEEHPKTAIVTDSITSEGLAKFINELQGRHHRFKRGYKNVI
                     NEAIRLNSEGEECHLAIETSGHAALKENYFLDDGAYLIAKILIKVAKLSLEGKTIEEL
                     IENLEEAQEEKEVRIGINKEDFRTYAEDILKDLDSHVKSIDGWSVAPNNFEGIRVNCD
                     ESNGDGWFLLRISLHEPLLALNIESNKIGGAEQIYSKLKLFLEKYDLKGL"
     gene            complement(37018..38607)
                     /locus_tag="PC465_002016"
     CDS             complement(37018..38607)
                     /locus_tag="PC465_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2649311.1"
                     /translation="MVTKLKNLIINDSKAKFILLLLLFLLVSILFEAVYDLNNNFSNI
                     NYYYREFALPHFYFFGTPVHLSKVELEFVCIGIILSSFLLTILCFTLYKKNKQTKVKF
                     LENVINLFSKVKIELTLILTLILLTLRFHAFTSNKMFYNTNLIIYNFIIISIVYIIYE
                     NIKYNNYNLKDMSITYVFFSNLLSMYNKKTINKKLAIVFLISIVVQAIIQYLVLIFFM
                     YIYYAEAIAIVILFTLVNTVFHFYIYNFLSVKFNYINNISKNIKNIENGNLKYKLEVI
                     GDDEISTLAKSINNITGGLETAVDANIKNERMKAELITNVSHDLKTPLTSILSYVDML
                     KNNDFDRETINDYINILDKKSQRLKLLIDDIFEASKLSSGDVEFNITKTDIRELLIQS
                     IVEFEDKIQNSSLDFIIETPEYAVFTMIDGKKTWRVFENLICNILKYSMPNTRVYIDM
                     FIKEENIILTFKNISNDKLNLKPEELIERFRRGDISRKTDGSGLGLSIAQNIIELENA
                     HMEIIIDADLFKVMLTFRRVN"
     gene            complement(38576..39292)
                     /locus_tag="PC465_002017"
     CDS             complement(38576..39292)
                     /locus_tag="PC465_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2649312.1"
                     /translation="MNQNILVVDDDREIVDAIEFYLRPDNFNVLKAYDGLEALDILIE
                     NDIKLIIMDVMMPNLDGLKTTLKIREKRNIPIILLSAKSEDMDKIIGLNMGADDYITK
                     PFNPLELTARVKSQLRRYINLGDFSNTNNSNDTNYILKSGGLELNTDTKIVSLDGEEI
                     KMTPLEYKILTLLMSRKGKIFSSHEIYENVWNEDAYSCERTIAVHIRRIREKIEINPK
                     EPKYLKVVWGIGYKIEKLNY"
     gene            complement(39831..40631)
                     /locus_tag="PC465_002018"
     CDS             complement(39831..40631)
                     /locus_tag="PC465_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HDF2649313.1"
                     /translation="MTFKNKKFTINKYKILSIILVLCLILTAFSSYVNYSHKKFKDYV
                     VFYVQHQDDEVLWAGSAIVNAIKERGKNHVFVVLVSTGCGISVFDKYKKYENLTNIQK
                     SEYRNREFLASLNSLGVIRENIILLPETNTNGNTDFNYMEKIALTFEEKFKNVTHIAH
                     TYKLDDHLQHLKNGSVIQNLYNAGKIKDAKYFVKPKFADKITFNNKIVYKAHSTEDYE
                     KVKNACQQYKIVDELEYREGIGYKSDHKSFDKLLNNKDVPAILHTPNL"
     gene            complement(40945..41676)
                     /locus_tag="PC465_002019"
     CDS             complement(40945..41676)
                     /locus_tag="PC465_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649314.1"
                     /translation="MNIFDILRDYLLVQVDKYNLNMDMISIVSKSLSSKEAIGNTKRK
                     DFPIIVGKEIMLEADFKGAKGQAFTSTPSTFEGSLKDILSLDLHDNSHDRSLFIASLN
                     AVMKYLGKTDRTIHCKNNEPEVCAKKFPEFIKMEFGNPKVAIIGYQPAIIDNIKDFFE
                     TRVLDLNPEFVDTIQYNVKIEDGIRDYEDVISWADLVICTGSTLCNNSIINFLSLNKP
                     VYYYGTTIAGASNILGLKRLCFCSK"
     gene            complement(41663..42358)
                     /locus_tag="PC465_002020"
     CDS             complement(41663..42358)
                     /locus_tag="PC465_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2649315.1"
                     /translation="MLKIKNLSLDLPNFKLQENSLNINNHEYFVLLGASGSGKTLFLE
                     TLAGRYPSAKGNVSYKENLISNLPPENRNIGFVYQNFELFPNMNVEDNIRFPLKLRKI
                     PIDEQILKANHLSKLMQIEDIKNRYPKNLSGGEKQRVAFARALIAEPDILLLDEPMSS
                     LDYITKKHISKILKDVYIKYKPTVIHVTHDISEAMFFAHKIGIMNNGKINHIFDLNEE
                     IKNKGESFFYEYI"
     gene            complement(42360..43151)
                     /locus_tag="PC465_002021"
     CDS             complement(42360..43151)
                     /locus_tag="PC465_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2649316.1"
                     /translation="MKNKFFTTLLTGFFAIVFLFIVSPLLMLIIKGISYVPICLKSVE
                     VQYAITLSIKTSLISTIVCLLLAIPVAYFLHITKLPFKKLIIQIINLPMSLPHLVSGI
                     ALLLLFGRMGIGDSIYKIFKLDFIFTKQGIVLAQIFVNLPLTIKILHTSLNESNEKMI
                     FVARTLGCNSWEAFRFIILPNLKTGIISATVMTWSRALGEFGAVAMIAGSTRMKTEII
                     PTSIYLNMSTGDIDIAIGIAVILIFLSLTCLMLFEIFFNREVDKN"
     gene            complement(43161..43973)
                     /gene="modA"
                     /locus_tag="PC465_002022"
     CDS             complement(43161..43973)
                     /gene="modA"
                     /locus_tag="PC465_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2649317.1"
                     /translation="MFKKLSVLALAMIISLSITACNSKENKANDESNTKVTTADDSKE
                     KETLFVYSGAGLKKPMDEIAKKFEKENNVKVEYSYAGSAQLIAQIETSHKGDVFIVGS
                     EPIYSKAFEKELVGEHKTVAHHTPAIVVPKGNPANIQKLEDLNKDGVKLILGDKESNA
                     IGKTTQKILEKNNLKSINDNVVSTAATVNEMIVQLTSSKADATIATKDSVFGNEDVEV
                     IEIAQDKNIDQLISAGIVNYSDKKDLANKFINYIESDEAKQIFKKYGFEPVK"
BASE COUNT        17239 a         5042 c         7711 g        14195 t
ORIGIN      
        1 aatttattat atttattcaa ttaaaattaa gctttctaac taaataaaaa ctaatgaagt
       61 attaaaatga aattgataaa atatgaaaaa attttaggaa taaagtatct gttagataaa
      121 aataagatta attagtgata taatataatt aagataaaat ttattatttg gaggtaaaat
      181 catgagcaga gtaaaaaatg tagtagaatt gttggaaact aaaggtgttg atgcactata
      241 tctaacaaag aaaactaatg taaactatat aagtggtttt cctgatgaag aagcatatgc
      301 agtgatttgc aaagatggaa actttttagt tactgatagt agatatatgg agcttgcaga
      361 aaaggtttgc aaagattttg aaattataaa ttggcataat tttgatagaa gtgtggcaaa
      421 ggcagttaaa agtgtatgtg ataaagtggg tataaagaaa cttgggtttg aaagaactaa
      481 tatagtgttt gataaatatg aagaacttaa aaatctgatt gagaaggata atggagaatt
      541 aatacctaca gaaaatattg tagagacttt gagatatgta aaagacaaag atgaaatcaa
      601 aaatacaaga aaagcttgtg aaatagcgga taaggcatta gaagaattga ttccacatat
      661 aaaagctgga gttagcgaaa ttgaactggc tacaaagtta gagtacttta tgaaaatgaa
      721 cggagcacaa aatatagggt ttgaaactat actgatatca ggagcaaaga cttcattgct
      781 tcatggtaag cctagtgata agattataga aaaaggtgat tttgtactta tagactatgg
      841 tgctatgtat aatggctata tatctgatac aactagaact tttatagttg gaggagcttc
      901 tgaaaagcaa ttagaaatat ataatttagt taaggaagct caaaatgtag gggttgagaa
      961 catgaaagct ggtgtacatg cgacaattcc agatgctgag ataagaaaag ttgtcaaaaa
     1021 atatgaagac tattactatc aaggtatagg acatggagtc ggtagagatg ttcatgaaga
     1081 acctttcatt ggtaattatg gtgataaaat catagaagag ggatgtataa taacaatgga
     1141 accaggtatt tatttccctg gatggggtgg agttagaata gaagatactg ttttgattac
     1201 taaaaatggt ccagaaagac ttactaaatt ccctaaagat ttgatgattt tagacaaata
     1261 atttaattta tatatatttt tttacataaa atataacata atctcactat taagctctat
     1321 ttacatatta tagtaaagag ggcttaattt tattgtgaga ggtgatagta tatatgtata
     1381 aaaaacataa atttataaaa aatataaaaa aagcctggta taaaattaaa ttaattgata
     1441 gatgccttat aattgtaatg gcaatattaa tgtttcaatc tatatataat ttatttgtta
     1501 atgaagtaaa ttcacaagat actacaacta ttgatgtagt agtaagaacc acttcagcag
     1561 ctatatttgg gtatttttta agtgctaatt ttataaagag acctttaagg aagtatacaa
     1621 atactgatgt atcttcaaat ctttttatag ataataattt atccccaaaa ggtcaagagt
     1681 ctaatcaaaa taatataatg aatgtcaaaa ataccattgg atttacttca gaagctgata
     1741 attatgaaaa gaaaatacct attaataata atgaaggttt tgaagaagga gaaactagtg
     1801 aattgcaaat tattatagct actgtaattt gtatagtagc attaacagta ctttttgttg
     1861 taagaaattt tacaactaca acatcagctt ctttaggtac tatttcacag atgagagatt
     1921 ttgtctcagg atgcgtgggt tttttgctag gttgtccaag taaacctgat taaaaaagta
     1981 ttatcaataa aaggtatttt aaaaagtatc agtataataa tatttagatt taaatgtata
     2041 caattataat tctataacat tctatattgt atttttatac tgatactcta aactatacta
     2101 tttattaaaa tattttaaca ttgtatttaa acaaaatatt atatctgtat aatataaatt
     2161 tagtttatat gaatagatgc catatactca ataaaaagtt tcatactatg agatatgtat
     2221 tgatttcttc tccaaagaac cccaatattt gcagtaattg cacgttctaa tggtattgaa
     2281 cagagatttt ctgtattttg aaatatttct ttatacaata ttgttgaagc caagtcattt
     2341 tctagtaaat aacgtatggt agaaagttga tttgagtgta aaattatatt tggcttagct
     2401 ttttcaagtc tttttgtaat aatcttatag tgataagaac cttcagataa gattacaaaa
     2461 ggtacatttt ttaacatata attcgatata ataggatgtt ttgccaattc atttttggga
     2521 tttgtaacta agtataattc tgttttatag attgtctttg aatctatatc atcataaata
     2581 tcactgtcaa ttataccaat acaaaaatca agtgtagatt cttcaatcat tttagctcca
     2641 acaaatgttg gaacttcaaa aattttaagc tctatatctg gataaattac attaaatcta
     2701 ggaagtattt ttgaaagcaa aaacgtacct aaaactgtag gaatacctat tttgagagaa
     2761 gcttttctct tttttcctaa atcaagtgcg tcacattgaa aatcctcaaa ttgttttata
     2821 aaatgttttg acttgtctaa aaaaattttt ccttcaggcg ttaactctat tttattacct
     2881 attctgtaaa aaagttcaaa gccaagttct ttttctaatt ctttaattgc taatgttatg
     2941 gatggttgag aaatatgaat actttccgca gccttagtca tgtttttata tttacagaca
     3001 gtttgaaaat agtataaata gtttatattc atttggtatt agttcctttc atttacatat
     3061 tagtgacaag tatataatta acaatagcat aagttttgta tattgttgta aaaaaataga
     3121 atagttttaa actatcatag cataagtttt tgatattttc aatctattaa gaatagtgct
     3181 attattaaat taacaaaaga gaatagctgg tatggtttag agtaaatcaa tctatattac
     3241 agttatatca acgaatatca aaaaattatc tattaaaaaa taaaaattat ttttacaatt
     3301 aaattgttaa ttaaatcata aagaaaaaag tgatattaac aagataaaat ttttttaatc
     3361 agaaatgtta atttaataac aaaatagagt attggggaga aaggagaaat atatttttta
     3421 ataatatttg ttaatttaat aacaaaaatg aaagggagtg atttagtgaa gtttgaattg
     3481 atggattttt taatgaatcc ttttgtcctt atgtttgctg cagtaattac aggaatttta
     3541 tttggaaaaa ttaaatttgg gaagtttaat tttggggtat caggagcatt atttacagga
     3601 ttatttattg gatggcttgc atatagcttg gggaatctaa taatagcaaa aggggaaaca
     3661 gcagcaggat ataaggcagc aactgtaatg atggggaatg gaattatttc ttctgacttc
     3721 tttgatttct ttttaataat atttgttgca gcagttggtc tattggcagc aaaagatatg
     3781 aaagctgtat taaagaagta tggagcaaga tttgtaattt taggagttct tataactttt
     3841 ataggtggct ctatgactta tgcaatgact ttactatcaa gtgataaagg aagtagtgct
     3901 tatgaagttt ctggcgttta cacaggagca ttaacaagtt cgcctggatt agctgctgct
     3961 ttagaaacag ctggtaaaca tgcagaagat gtatcaaaag aatttgaaaa agcatcaata
     4021 aaagataaaa aagaaatttt aaaagtagtc gacccagaag gcaaattgga tgtgaataca
     4081 actacatcac tgactcaaga gcaaatagat aagtatattg catatgctga agctggtgtt
     4141 ggtataggtc atgcagtcgc atatcctttt ggagttttaa tagtaatctt aggtgtaaat
     4201 ttccttccaa aattatttag gatggaccta aaagaagaaa gaagaaaata tgagaaggaa
     4261 atgaaggaag caagagatag tgtttctggt aaaacgatac cagaagttcc atttaatata
     4321 ataacatttt tcttgacatg tttagctgga tacttagttg gaggaataca tgtatttatg
     4381 ggaccactag ggtacttcac actaggtgca acaggaggtt cactaattgt atctctagtt
     4441 cttggatata taggtaagat aggggtagta aatttcagaa tggaagaaaa ggttttaaat
     4501 attttaaaac aaatagggct agtatttttc ttagcaatag ttggattaag atatggtgga
     4561 aaagtagttg attcaattat gacatctggt atgcacctag ccttagtagc aatagcagta
     4621 ggtgttacag ctatgatgat aggattctta gttggcaaat acgtatttaa attaaattgg
     4681 attttattat ctggagctgt ctgtggtggt atgacatcaa caccaggtct tggagctgct
     4741 gttgatgctc ttgatagtga tgacccagca gcaggttatg gcgctacgta tccatttgca
     4801 ttattaacta aagttatatt ggttatagtt ttacacaaac ttccaatgta aataagattt
     4861 tatatggggg gatatttatg aataatgaag gagcatttga agaattaagt ggaagattaa
     4921 gaaataaaga attgtgtgat ttaataatga atgcagatga agctgctaaa attatagagg
     4981 atggcatggt tattggagtt agtggattta caccttcagg ctatccaaaa gcagtaccat
     5041 tagcagtttc agaaagagct aaaagtggag aaaagataaa attaaccgta tattcaggag
     5101 catctttagg tccagaagtt gatggagcat ggtcagaagc aggtataatt gaaagaagac
     5161 ttccttatca aactaattca atacttagaa ataatattaa taaaggtgtt gttgattata
     5221 tagatatgca cctaagtcat tctactcaat ttttaaatta tggaactata cctaaagtag
     5281 atgtagctat agtagaagca cttgcaataa ctgaagaagg gaatattata ccaactagtg
     5341 ggataggtaa ttctccatct tttataaaaa gtgcagataa agtaatagta gagataaatc
     5401 ttgcaaaacc aatggaaatg gaaggtatgg cagatatata tattacggaa aatccaccaa
     5461 atagaaaacc aatagaaata aatcatccta aggatagaat tggaacaaca tatatacctt
     5521 gtggtttgga taaaattgca ggagtagtaa ttaccaatat gcaagataag acccgtccat
     5581 tgggggttgt agatgaagct tcgaaaaaaa tatcaaataa tattattgct tttttaagag
     5641 aagaagtaaa ggcaggcaga ttatcaaaga atttacttcc tcttcaatct ggtgtaggaa
     5701 gtgtagcaaa tgcagtatta tatggattat gtgaatctga atttgaaaat ttaacttgtt
     5761 atacagaggt tgtacaggac tctatgttgg atttaataag aatgggtaaa gttacaatgg
     5821 catctactac atctgtaagt ccatctccag aaggattaat aaaatttgaa aaagatattg
     5881 atttttttaa ggataagatt atattaagac ctcaagaaat tagtaacaat ccagaaatag
     5941 ccagaagaat tggtgtaatt gcaatgaaca ctgcaattga agttgatatt tatggaaatg
     6001 taaattctac tcacataatg gggtcaaaga tgatgaatgg aattggtggt tctggtgatt
     6061 ttgctagaaa tggagcaata actatattta gtactgagtc aattgcaaaa aatggtgata
     6121 tatcatcaat agtacctatg gtatctcacg tagaccacac tgaacatgat gtaatggtaa
     6181 ttgtaacaga acaaggatat gctgatttaa gaggtcttgc acctagagaa agagctataa
     6241 aaataataga aaattgtgcc catccagatt ataaagaaca acttagggat tatttaaata
     6301 gagcttgtaa aagtggagca aaacaaacac ctcacatatt ggacgaagct ttatcatggc
     6361 atagtaaatt tatgagtaca ggtacaatga aaaaggctga aacttttaaa agtgcattat
     6421 aaaatattta ataaattgga ggtagatttt aaatggaaaa agcagtggaa aactttgaag
     6481 atttaagtaa ggaatacatt aatggttata ttgagagagc aagaaaagct caaagagagt
     6541 ttgaatgtta tactcaagaa caagtagata aaatagtaaa aatagttgga aaagtagtgt
     6601 attataatgc tgaatattta gctaaacttg ctgtagaaga gactggaatg ggagtatatg
     6661 aagataaggt agctaaaaat aaaagcaaag caaaagttat atataacaat ttaaaagata
     6721 aaaaatcagt tggtataatt gatatagata gagaaactgg aataacaaag gtagctaaac
     6781 cagttggagt agtagcggca ataactcctt gtacaaatcc aatcgttaca cctatgagca
     6841 atgcaatgtt tgcacttaag ggaagaaatg caattattat cacacctcat cataaagcaa
     6901 ttggatgtag tacaaaaact gtagagatga ttaatgaaga attagaaaaa ataggagctc
     6961 cagaaaattt aatacaaata cttgaccaac aatcaagaga aaatacaaga aatttaattt
     7021 catcagcaga tgtagtaatt gccactggag gaatgggaat ggtaaaagct gcgtactcaa
     7081 gtggaaaacc agcacttggt gtaggggcag gaaatgttca atgtatcata gatagagatg
     7141 tagacattaa agaagcagta cctaaaatca tagcaggaag aatttttgat aatggtatca
     7201 tttgttcagg tgaacagtca gtaatagtag cagaagaaat gtttgataaa ataatggatg
     7261 aatttaaaaa taacaaaggt tttatagtta gagataaagt acaaaaagaa gctttcagaa
     7321 atgctatgtt tgtaaataaa tctatgaata aagatgcggt aggtcaatca gttcatacaa
     7381 ttgcaaaaat tgcaggtgtt gagataccag aagatacaaa aataatagta atagaagctg
     7441 atggaccagg agaagaggat attattgcaa aagaaaaaat gtgtccagtt atatctgcat
     7501 acaagtataa aagttttgaa gaaggtgtag ctattgcaaa agcaaattta aatgtagaag
     7561 gaaaaggaca tagtgtatct atacattcaa atacagttaa aaatatagaa tatgcaggag
     7621 aaaatataga agtatcaaga tttgttatta atcaatgttg tgctactagt gctggaggaa
     7681 gtttctttaa tggtcttgca cctactaata ctctaggttg tggttcttgg ggaaataaca
     7741 gcatctctga aaatcttgat tataagcatc taattaatat ttctagaatt gcttattata
     7801 tgccagaaaa tgaagtccct acagatgaag aactttgggg ataaaattta gacaaaaaat
     7861 attcattcta aattaaagta ggaatatatt ttaatttaga atgaatttaa gacataaatt
     7921 aaatttaaat tagtttattg gactaaattt aaaatattaa gagacatata gaagaaggaa
     7981 gtattataat ttaaaataaa taaaaaaatc tataaaagag aaggagtggt tttattatgg
     8041 cattaatgac aggagctcaa tatattgaaa gtttgagaaa attaaatact aaggtttata
     8101 tgtttggtga agaggttaag aattgggttg accatcctat gattagacca tctataaatt
     8161 gtgtagcagc aacttatgac ttagctcatg acccagaata tgcagattta atgacagtta
     8221 cttcaaatat cacaggtgaa aaaataaata gatttggtca tcttcatcaa agtgttgatg
     8281 atttgataaa aaaagtaaaa atgcaaagac tatgtggtca aaaaacagct tcttgtttcc
     8341 aaagatgtgt tggtatggat gcgtttaatg cagtgtattc aacaacattt gagtgtgata
     8401 aagcccatgg aactaattat catgataatt ttgtaaaata cttaacttat atacaagaaa
     8461 acgatttagt agttgatgga gctatgactg accctaaggg agatagaagt ctatcaccta
     8521 gtgctcaacc tgacccagat atgttccttc atatagtaga aagaagagaa gatgggataa
     8581 ttgtaagagg agcaaaggca catcaaactg gttcaataaa ttcacatgag caccttataa
     8641 tgcctactat aagtatgact gaagcagata aagactacgc tgtatcattt gcagttcctt
     8701 cagatgctga aggagtgttt atgatttatg gaagacaatc ttgtgacact agaaaattag
     8761 aagaaggtgc agatgttgat ttaggaaata aggagtttgg aggtcaagaa gctttagtag
     8821 tatttgataa tgtatttgtt ccaaatgata gaattttctt atgtggagaa tgggatttct
     8881 ctggtatgtt agtagagaga tttgcaggat accatagaca aagttatggt ggatgtaaag
     8941 taggagtagg tgatgtaata ataggagcag cagctttagc agctgattat aatggagcaa
     9001 acaaagcttc acatataaaa gataaactaa tagaaatgac tcaccttaat gaaagcttat
     9061 attgctgtgg tatagcatgt tcatcagaag gtcacaaaac agaagctgga aactatcaaa
     9121 tagatttact tcttgcaaat gtgtgtaaac aaaatgtaac tagatttcct tatgaaatag
     9181 taagacttgc agaagatata gctggagggc ttatggttac tatgccttca gaaaaagact
     9241 ttaaatcaga ccttaaagtt ggaacaagtg gaatgactat tggcgaagta tgtaacaagt
     9301 attttaaagc ttcttcagtg gcttcaacag aagaaagaat gagaatatta agattcttag
     9361 aaaatatatg ccttggttca tctgctgttg gttatagaac tgagtcaatg catggggcag
     9421 gttcaccaca agctcaaaga ataatgattt caagacaagg aaacataaat caaaagaaag
     9481 aattagctaa gaaaattgcg ggaataaaaa aagaggaagc tttaaattta taaaaagttg
     9541 atatataaag ggaaattata tattaatgtg tgttaattaa tgaaaaaata tgtagtataa
     9601 gagatagtta taaaattatg gtggttttta gctaagtaaa gaaattttta ataaggagaa
     9661 tttacacatg acctgtggag ttagattttg tgggggctgt aaccctagat acgaaagagg
     9721 gaaggctctt acaataatca aagagcactt caatggtagg gtagatttta gtatagcaca
     9781 agagaacgtc gagtatgatt tgttacttat aattggagga tgcgcaactc tatgcgcatc
     9841 ctatcaacaa tataaagtga aaaatgaatg tgttaagatg tgggatttta gccatataga
     9901 aagagttata aatgtgattg aatcagcaat ttgtgaaact taaaaaagct aaatgggggg
     9961 atttcattga gttggcaaga attgtatcaa agtaaattat gtagtgctac agaagctgta
    10021 aaacagatta aaaacggtga tactgtagta tttgcacatt gtgtaggtga acctcctgca
    10081 ctagtagaag ctatgattga aaatgctgaa caatataaag atgttgagat taaacatatg
    10141 gtaagcttgg gtagtggtgg atatactgct aagggaatgg aagctcattt tagagtaaat
    10201 ccaatgtttg taagtggaaa tgtaagaaag gcaattgaaa atggagatgg tgattttaca
    10261 cctgcattct tccatgaagt accaaagttg cttagagaaa aaagattaaa atgtgatgtt
    10321 gttttagcac aggtaactcc accagatgaa catgggtatt gtagcttagg aacatcagtt
    10381 gattatactt atgaagccat taaaactgct agaacagtaa ttgttcaagt gaatgaccag
    10441 tttcctagaa cctatggtga ggtagtccat gtatcagagt ttgactatat agtggaaaaa
    10501 tcacaacctt tatttgaact acaacctgca aagattggag aagtagaaga agcaattggt
    10561 aaaaattgtg cttcattaat tgaagatggc tctactttac agctagggat tggtgggata
    10621 ccagatgcag ttatgttatt tttaactgat aaaaaggatt tagggattca ttcagaaatg
    10681 atttcagatg ggactttggc cctttatgaa aaaggtgtta taaatggtaa atataaaaat
    10741 tttgataaag aaaaaatgac agttaccttc ttaatgggta ctaaaaaatt atatgacttt
    10801 gcaaataata accctgcagt agaggtaaaa ccagtagact atgtgaatca tccagcaatt
    10861 ataatgaaac aacataagat ggtttctata aattctgcta tacaagttga tttaatggga
    10921 caggtagttg cagaggctat gggacttaga caatttagtg gtgttggagg tcaagttgac
    10981 tttatacgtg gagtgtctat gggtgaagat ggaaaggcaa ttatagctat gccttcaata
    11041 actacaaaaa aagatggtac agtaatttca aaaatcgtat ctattgtgga tgaaggtgca
    11101 cctataacga catcaagaaa tgatgttgac tatattgtaa cagaatacgg tatagcagaa
    11161 ttaaaaggaa aatctcttag agaaagagca agaaatttaa taaatatagc tcatccaagt
    11221 gtaagagaaa gtctagcagt agaatttgaa aagagattta aggagaaata ttaataatag
    11281 aggggtgtta ataatggaag cacttagagt agttccaaag atattttact ttgatacatt
    11341 taaagaattt aatgaagaat ttaaaatagg aaaaaatgat ttagtaatta ctaatgagtt
    11401 tatatatgag ccatatatga aacctcttgg aatagataca aatttaattt ttcaagaaaa
    11461 gtttggaaca ggtgaaccat ctgatgaaat gatagactcc atgacaaagg aaatgaagaa
    11521 atacaatttt gatagaatta ttgcatttgg aggaggaaca atagttgata tatgtaagat
    11581 attagcactt gatgttccag aaaagtctat tgatttattt gaaggagaag tatcacctaa
    11641 aaaagtaaaa gagttagtag tagttcctac aacatgtggt acaggtagtg aagtaacaaa
    11701 tgtagctatt gcagagttaa aatctaaaca tactaaaaag gggcttgcag tagaagaaac
    11761 atatgcagac tatgcagtgt taattccaga gacagtaaaa gggttacctt acaaattctt
    11821 tgttacaagt tcggtagatg ctcttataca tgctattgag tcttatcttt ctccaaaagc
    11881 aagtccattt acagagatgt attctctaca agcaataaaa atgattatgg atgggtataa
    11941 gaagatagtt gataaaggag aagaagagag atttaatcat cttagagact ttgtacttgc
    12001 atcaaattat gcaggaattg cttttggaaa tgctggttgt gcagcagttc atgcactatc
    12061 ttattcaata ggtggagctt tccatgttgc acatggtgaa gcaaattatc agttctttac
    12121 tgaagtattt aagatgtatt ctagaaaaaa acctaatgga aaaattataa aatgtacaaa
    12181 aattttagca gatgcccttg aatgtgaccc taactgtgat gtttatggag aattagaaaa
    12241 gtttttaaat aaattaatag ctaaaaaagc tttgagagaa tatggaatgg ttgaaagtca
    12301 gatagatgaa tttacagata gtacaatagc aaatcaacaa cgactacttg ctaataatta
    12361 tgtagaactt agtagagagg aaataagaga gatatttgca aatctttatt aatacaattt
    12421 tttatttata tgtatagtca acataaacaa tgctaattat atttatgtac aaataaaaat
    12481 aagggaactt aaattttaat taaagttaag ttctcttatt tttatatgga gttaaatata
    12541 agtatatttt taatttaaaa tatgcttata tttaagtcta ttactttatt tgaaacaatt
    12601 tgtagaattt caaattcctt gacagtaata agtaagtaat tgtataatca aactgcaata
    12661 tattaataat attagtgaaa atgaaaggat tataaaatat gtataaatca gaaaattttt
    12721 caaaaaaatc tgtattaata aattcatttt taagtaaatt tttaaaaata attggatggg
    12781 gtttggtaag cttatttaca ttatcagcct tagtactttc aactatttcc attataattg
    12841 gatgggctgt aatacttcct attcaagtat gtgcagtatt tttacttata ggaggagttt
    12901 gtatttttaa aggtaagaga ttaggagacc aaatttctcg ttataaaaaa tattgtacaa
    12961 ttataaacaa tagaaatatt attccagtag aacttattgc agaaaacaca tctaaatcat
    13021 taaattttat aataaaagat gtacaaaaga tgatagacaa aaactacttt ataaatactt
    13081 atattgataa aagaaataat cagattgtgt taacaaatga agattttatt ccaccaagat
    13141 atgaagatgt agcatatgaa gtcaaagaag aagaaaagac tgatgaatcc aatgaagttg
    13201 atacaattat aaataaagga atgaattatc taacacaaat aaaagaagct aataaaaata
    13261 ttaaatcaga atcaatgggc aataaaattg tacaagtaga agatgttaca agtaaaatat
    13321 ttgatgttgt aaaacatgac ccatcaaaac ttactcaaat acaaaaattt atggattatt
    13381 atcttccaac cactttaaaa ctattaaatt catatcatac attggaagaa caaggaattg
    13441 atagagaaaa tataacaaca actatggaaa gtattgaaaa tacaatgaat acgattgtag
    13501 tagcttttga aaatcaattg gactatctgt ttgaagatga agccattgat atttctacag
    13561 atattactgt tttagagaat atgttagtcc aagaaggatt aacgagtggt aaattttaac
    13621 ttcaatagaa aaaatattct gttattttta aacaattaat tagtcataaa gtataaaatg
    13681 tgtattatat aagttaatca gtactttatg aaggaagagg agagaaagat acaatgaata
    13741 atttagatga tataccagtt atgccaactt tgacacttga cccatttgga gaagaatcaa
    13801 acactaatga tatagataat tctgacttat taatgaaaaa ggatgaaaaa gacccagaag
    13861 aagaaaaact gtctgaatct gaacgcaaga tggtaaagga atttgcggaa aaaatagata
    13921 ttacaaatac aaatatgatt ttgcaatatg gagctggtgc tcaaaaaaag gtagcaagtt
    13981 tttctgaaac agctttaaag agtgtaaaaa caagagattt aggagaagtt ggagatatgc
    14041 ttacaaatct agttactgat ttaaaagcat tttcagcaga tgaaaaagaa caaagtggtt
    14101 ttttaggaat ttttaaaaag gcaaataata aaatttcaaa tttaaaaact aagtatgata
    14161 gtgcagaggt aaatgtggat aaagtaagca aagagcttca aaagcatcag gttaaaatat
    14221 tgaaagatat agcaatgctt gataagatgt atgaattgaa cttagcttac tcaaaagagc
    14281 ttactatgta tattatagca ggaaaacaaa aattaaagga tatgaaagaa tatgagatgc
    14341 caaagttgag agaaaaagct cgtttatctg gttcaacaga agatgctcaa tctgtaaatg
    14401 atatggtttc actttgtgac agatttgaaa agaaaattca tgacttagaa ttaactagaa
    14461 tggtatcgct tcaaatggct cctcagataa gattggttca aaatagtaat aatctgatgg
    14521 cagaaaagat tcaatcaact atagtaaata ccattccatt atggaaaaat caaatagtgc
    14581 ttgctcttgg aatttctcac ttaaatcaag ctatgaaagc acagcgtgaa gttagtaata
    14641 tgacaaatga gcttttatta aagaatgcag aaactttgaa gatgggaaca atagaaacag
    14701 caaaagaatc agaaagagga attgtagata tagacacaat taagaaaacg aatcaatctc
    14761 taatatctac tattgatgag gtagttaaaa tacaacatga tggtagaata aagagacaag
    14821 aagcagaagt tgaattatca aaaatagaaa atgaacttaa aagtaagctt cttgaattta
    14881 cagttaaata aaaattatac taatataaaa agagactgtc tcaaaataga gataagtctc
    14941 tttttcattg tttaaatgat taaagtatat ttatattata aatttctatt atcttttaac
    15001 ataacatcat gagctccacc ttcaactata ctagtagaag atacaagtgt aagtttagca
    15061 tttttttgaa gttcaggaat gctaagtgct ccacagttac acatagtaga acgaacttta
    15121 cttaaagaaa gagttacatt gtctttcaaa gaaccagcat aaggcacata agagtcaaca
    15181 ccttcttcaa aagaaagttt cttatctcca ccaaggtcat atctttgcca gtttctagca
    15241 cgagcagaac cttctcccca atactctttc atataactac catttatatt aactttgtta
    15301 gttggactct catcaaaacg agagaagtat ctaccaagca ttataaaatc tgcacccata
    15361 gctaaagcta aagttatatg atggtcataa acgataccac catcagagca aattggaata
    15421 taaatacctg ttttttcaaa gtattcgtct ctagcttgag caacttcaat tatagaagta
    15481 gcttgtccac gtcctatacc tttttgttca cgagttatac atatagaacc accaccaata
    15541 ccaactttaa cgaagtcagc accagcttca gctaggtaaa ggaatccttc gcggtcaact
    15601 acatttccag ctcctacctt aactgtatca ccatattttt cacgaatgaa atcaagtgtt
    15661 attttttgcc actcagaaaa accttctgaa gaatctatac ataaaacatc agcaccagct
    15721 tcaactaaag caggaacacg ttcagcaaag tctctagtat taataccagc tccaactaca
    15781 tatctcttag aagaatctaa aagttcaagt ggattttctt tatgagaaga gtaatcttta
    15841 cggaatacca tatacataag attaccatta tcatcaagta caggaagaga attaagtttg
    15901 tggtcccata taatgttgtt tgcttccttt aaagtaacat ctttgttagc ataaactata
    15961 gatgacatag gagtcataaa ttcactaact ttagtatcta aatccatacg acttatacga
    16021 taatcacgac ttgcaacaat acccaataat ttaccagttg aagttccatc ttcagtaaca
    16081 gctactgtag aatgtccagt tttttctttt aagtcaagta tgtcttttaa tgtgttatca
    16141 ggtttaatat ttgaatcact tacaacaaaa ccagctttgt gggatttaac acgtgctacc
    16201 atagcagctt cattttcaat agtttgagaa ccgtatataa atgaaatacc accttcttta
    16261 gcaagtgcaa tagccatttt gtcatcagaa acagattgca taatagcaga agtcaaaggt
    16321 atattcatat aaatatctgc ttcctcgccc tttttaaatt tagtaacagg tgtttttaaa
    16381 cttacattag caggtataca atcagtagaa gagaaacctg gtacaagaag gtattcactg
    16441 aaagtatgtg atggtgtatc aaaataaaac gccatttttt aatcactcct tatattttta
    16501 tactttttat aattgatagt attaattata acttattctt taattttatt aaagtatttt
    16561 gtcaaatatt gagatttttg aaaaatttaa actattttaa ttaaatttgt ttaatatata
    16621 ttgccttata gggtaaagtt gtatattaaa taatgtttag tgtttaatag tagctaattt
    16681 aaaattaatc tttagtgatt catataatta catttgtata gtttatattg ataatattac
    16741 tagagagtgt ataaacctca aaaatacaga taaattaaat ctatattagt atatccaaaa
    16801 gtacatttaa taaatttatt taactgaatt attattttca tttctattaa atttaaatat
    16861 tttataaaaa tagtattatt tacaaaatca tatactccaa aatactacat aaataaaatt
    16921 aaacaaaaac taaaatgaca aatgtcatta tctaaagtga catagaaacg gtttcttaaa
    16981 gttgttacta taaaatataa actctataat aaaagtataa caaaagggaa tcatatcgat
    17041 atagaatata attcaagagg aggtaaaatt atgagtagtt ctaatcaatc gacaataaag
    17101 acatctatac agcgagtagg gaaattttta agtggtatgg taatgccaaa tataggagct
    17161 tttatagcat ggggtcttat aacagcatta tttataccaa caggatggat gcctaatgaa
    17221 aaattgagta ctataggtga cccaatgata aaataccttt taccactatt gatagcttat
    17281 actggtggta aagcaatagc aggacaaaga ggtggcgtaa taggtgcagc agcagctatg
    17341 ggagtaattg ttggtgcaga tataccaatg tttatcggag caatgataat gggaccattt
    17401 gcaggatggg taattaagaa gtttgataaa tttgtagatg gaaagatacc aacaggattt
    17461 gaaatgttag taaataactt ttcaataggt ataataggta tgcttcttgc aatactagga
    17521 ttttatgcaa ttggaccagc aatagtagca gggacagctc ttatagaatc tggagttcaa
    17581 tttatagtta gcaaaagttt attgcctcta gtttcagtat ttatagaacc tggaaaagta
    17641 ttattcttaa acaatgcaat aaatcatggt atattagggc ctataggtat agctgaggca
    17701 aaagaagcag gtaaatctat aatgttctta ctagaaagta accctggacc aggtttagga
    17761 gttctattag catattggat gtttagtaga ggaagtgtaa aacaatcagc accaggagct
    17821 gtaataatac atttctttgg tggtatccat gaaatttact tcccatatat tttaatgaat
    17881 ccagttttaa tattggctac aatggcaggt ggagcagcag gaatattgac tttttcaata
    17941 ttaggagctg ggcttgtagc agcaccatca ccaggaagta tatttgcact tatggcacta
    18001 gctccaaagg gaggattact tccagtatta gcaggagttg cagtggcaac agttgtatca
    18061 ttcttagtgg cagcaccatt tgttaagaga gcttcagcaa atcaaagtga agaagacagt
    18121 acttctttag aagaagctaa agcaaaaatg agtgatatga aatctgcaag taagaactct
    18181 gagaaaaata ttgacgaaaa acagcttgaa gtaaatgaga ttaagaagat tgtatttgca
    18241 tgtgatgcag gaatgggttc gagtgcaatg ggagcttcca gatttaaaaa tagaataaaa
    18301 aacttagact taaatataga aattacaaat tcatctgttg ataatcttcc agatgataca
    18361 caaatagtag taactcacaa tacattagtt gaaagagttg ctaagaataa ttcaagtgtt
    18421 gagatagttt caataaacaa ttttttaaat gacccaaatt tagatacatt gtttaaaaga
    18481 ttagaatcta aataaaaata aaaagtacca ctaattagga gtggataatt tgaaaaaaaa
    18541 gaagattaca tctaggcaaa aaaagataat actaatgata gtagaaaatt caaagaaaaa
    18601 cattccaata actatttctg agattgcagg gactttagag ttaagttcaa gaactgtact
    18661 tagagatatg tctggaattg aaaaatggtt tgatgaaaat gattttaact ttgtaaaaaa
    18721 accaggagtg ggattgattt tagaggaaaa tatagaaaat caaaacttta taattgagtt
    18781 gttagaagaa gaaaaaatag aaaaagaata cagcaaggaa gaaagaaatt taattatatt
    18841 atcaaagcta ctagtttcta acgagccagt aaaatcctat tattttgcaa aaatattaaa
    18901 ggtatctgaa ggggtactga ataatgattt tgccttagca agtaaatggt tggaaagatt
    18961 tgatattgag cttgttagaa aaccagggct tggtgtctat ttaaaaggtc aagaaaaaag
    19021 ctttagagag gcatatgtaa atcttatata cgattcattc aatgaaaaag aaatactaga
    19081 tatggtcaga aatataagtg aaaatataca aacagataaa gcaatagaaa ttttaagtga
    19141 aaatagactt ttaaatttaa tggacaggtg cataataaga aaagttgaag ctacattaac
    19201 aaagaagctt tcagatttag atgtaaattt agctgatagt gcatatatag ggcttgtagt
    19261 tcatatttca ttagccttac agaggataaa aaatggtgaa aatataacta tggataaaga
    19321 gtttctaaaa gaattatcta taacagaaga gtttaaatta gctaaagaaa tcgtaaaagg
    19381 tatggaaaca gattttaaca tggatatacc agtagatgag gttggatata taaccatgca
    19441 tataagaggt gcaaagcaaa ggtcatcttc aaaccataag gctttaaact tagatgatat
    19501 agaaataatg gaaattacaa ataagatgat agatttggcg gaagatgaat ttaaaataag
    19561 tttaaaaaat gacgagaggt tatttaaaga cctagcaaat cacttagggc cttctataaa
    19621 tagattgaat atgggattag aaataagaaa tcctctttta gatgaaataa aaagcaagta
    19681 ttcatatgcc tatgatggag ttgaaaagat ttctagaatt ataaaagata aactaaatat
    19741 aaattcaata cctgaatcag aaataggata tattgcaatg cactttgcat cagccataga
    19801 aaaaaatctt atgatgaata ctaatataaa tattgttgtg gcatgtccca ctggaatagg
    19861 tacttcaaga ttcttatcaa ctaagattga aaataaattt cctaatttaa atatacttga
    19921 aaccatatca gctataaaca tagatgaaga gtatttaaag gaaaaagatg ttgatttaat
    19981 agtgtctaca gttgagttaa atacaagttt aaattatata tgtgtaggtc catttatgag
    20041 tttagatgat gaacagataa tcaaggaaaa aataaaatct atagctcaaa ataaattaat
    20101 caatttaaat gcgaaaaatg atactaagag taagaataaa gtatatgaac agataacaga
    20161 aagtatgaat ataggaaaag atattcttca atttttagag gaaattagat ttgaaaaatt
    20221 tgaaagtaaa gatttaagtg agcttattga agactcatca agaatatttg caaaatctag
    20281 tgaagatata atctctataa aagaatcgtt aaaagaaaga ttaaaaatct caattccata
    20341 tatagaagaa tcaaaaattc tattgttaca ttgtatgagt gaaagaatag atattatgaa
    20401 gttatcaata ataaaactag agaatagaat cgtgctagat tcaaatgaag aaatcgacaa
    20461 tgtagttttt atgttacttc ctaaaaattc accaagttat caaagacaaa taatgagtga
    20521 aataagtggt tcattaatag acaatataat ttttactaat aagataaata aattctctat
    20581 agaagagatg gcattagagg taaaagatat agtttttaat ttttatacaa acagattaaa
    20641 agcatttata gataaataaa attaatatta aaaaggaagg ttgatactat gagtaaagta
    20701 ttgaatgaga ataatatatt tttagggtta gatagtgttt caaaggaaga agctataact
    20761 ttagcaggaa gaaaattagt tgaaaatgga tatgtaaaag aagaatatat accagcaatg
    20821 ttagaaagag aaaaagtaat gactacatat atgggaatgg gagttgctat tccacatggt
    20881 gtaaatgaag caaaaaaaga aatattatct tctggaatag ttatattaca attccctaat
    20941 ggtatagatt ttgatggaga aaaagcatat ttattaatag gaatagctgg tgttggagat
    21001 gaacatttag aaatactatc taatatagca gtagttttag atgatgactt aacagaaaga
    21061 ctaaaaaatt caaatgacaa acaagctttt atggaagctt ttgccaacta atcttaggag
    21121 ggatttaaaa tgaaaaaggc aattcagttt ggagcaggaa atattggaag aggttttatt
    21181 ggaggcttgt tagttaagtc gggttatcat gtagtatttg ctgatgtaaa tgaggatata
    21241 ttaaactcaa taaacaaaga taaaaagtat actatacaca taagagatgt agaatgtata
    21301 gatgaagtaa ttgataatat aagtgcggtt tcatctataa aagaagaaat aatagatgag
    21361 attgtacagg ctgaaataat aactacagca gttggacctt tagttttgac taaaatagcc
    21421 tctacaattg caaaaggtat aaaggctaga aaagaaaagg gattaacaag taatctaaat
    21481 ataatagcat gtgaaaatgc aatatacgca agttcttctt taaaagaaga ggtacttaag
    21541 tatttaaata aggaagaagt agaatattta gagatgtatg ttggttttcc aaactgttca
    21601 gttgatagaa tagttcctcc tggtaaaaac gaaaatcctc ttgatgtaac agttgaaaat
    21661 ttttatgagt ggaatgttga aaaacaagga tttaaagggg aaataccaac tatagttgga
    21721 atgaatttag ctgataatct tatggcttat atagaacgta aattgtttac actgaataca
    21781 ggtcatgcta taacagctta tataggatat ttaaaaggat ataagactat agaagagagt
    21841 ataaaagata aatttatctg tgatatagtc aaaagtgcaa tggtagaaag tggagaagga
    21901 ttgattaaaa aatacaattt tgactcagaa gtgcactata aatatattga taaaatttta
    21961 aatagattta aaaatccata tcttaatgat gatgtattaa gagtcggaag ggaaccatta
    22021 agaaaactaa gtgataaaga tagattgatt aaacctttaa tgacagcaaa atcatatgga
    22081 ttatcagttg ataatttgat tcttggaata ggtgcagcgc ttcattataa taatagtgaa
    22141 gatactcaaa gtgtagaatt acaagagttg ataaagtcta ttggggtaaa aaaagccgtt
    22201 gctaaaatag ctaatataag caatgacgaa gaacttttaa ataatatcga aaaaagttat
    22261 atatttatga aaaatttata aatttacttg aaaaaaagta gttctgataa agtaactata
    22321 atatattatt ctacacagtt tgaattattt gttgaataat agagaattat aatatataat
    22381 taaaaggaat aaattaatat atttacctgt atatgtttga taatatggtt caaatgtttc
    22441 tactaagcta ccattaatag cttgactaca ggagtgaaga agatatagtt tatacttatt
    22501 ttaaattata tattaagtta attactttga attttaagct cctgtctatg atatagacag
    22561 gagctttttt agtattttaa tataaaatac ttacaagaat agatagcaaa attagaacaa
    22621 atataatttt tttattaata taattttaga aagggctagg tggaagttca atgaaggctt
    22681 tacaagaaaa gatattgaga gaaggcagtg tttcaggaaa tgatatacta aaagttgata
    22741 gttttttaaa ccatcaaatt gatgtagctt ttttaaatga aataggaaga gaatttaaag
    22801 agagatttaa aggagaaaag gtggataaga tatttacaat agaggcttca ggaatagcta
    22861 tagcatcaat tgtttcacag tattttgata atgcacctgt agtatttgca aaaaaatcag
    22921 aatctaaaaa tttggataaa gatgtatatg aaactaatgt atattcattt actaaggcaa
    22981 gagagtattc agttaaagtt tctaaaaagt acataaacaa aggcgaaaat atattgatag
    23041 tggatgattt tttggcaaat ggaagagctg ctcttggact taaagattta attgagcaag
    23101 cagaagctaa cttagttgga gtaggaattg tcattgaaaa aggatttcaa gctggaggag
    23161 cacttttaaa ggctaatgat gtaagattag agtctttggc agtagttgaa tctatagata
    23221 atggaactgt aaaatttagg taatttatga tattatatac ttgtgtttag cacatatttt
    23281 aactatgtaa ttatggagga ttttttatga gattttttat agacacagcc aatattgaag
    23341 aaataaaaga agcaaatgat ttaggtgtaa tatgtggtgt aactactaat ccgtctctaa
    23401 tagctaaaga aggtagagat tttatagagg tagttaaaga aataagtgaa atagtagatg
    23461 gaccaataag tgcagaagta ataagtttag aacataaagg tatgatagag gaagcagaaa
    23521 aattatctaa gatacataaa aatatagtta taaagatacc tatgacagca gaaggtctaa
    23581 aagcggtgaa agtactatca agtaaaggta taaagactaa tgtaacgctt atattctctg
    23641 ctggacaagc tcttttagct gctagagctg gagctacata tgtaagtcct tttgttggta
    23701 gattggatga tatatcacaa aatggtcttg atttaattga agaaatcgtt gatatattta
    23761 gtgtaaatag tattgaggct caaataatag ttgctagtgt tagaaatcca atacatgttt
    23821 tacaagctgc tagaatggga gcagatatag caacagttcc tcttaaagtt ataaaccaaa
    23881 tgattaagca tcctttgaca gacaaaggaa tagatagctt tatgaaggat tgggaaggtg
    23941 cttctttaaa attataatta taaactacgc tttataatta tattaaagag gttattatgg
    24001 aaattctaag taataaggct aggctatttt gcctagtctt attttggtgt ataatatatt
    24061 gaaacatatt attgaaatag attaattttt taagtgagga ggcgaaaaat ggataaaata
    24121 ttaagagaga tacaaagaga agataaaaaa aatccatata ctgaccaaga acttgctgaa
    24181 atgttaaatg tagctaggtc tgaagtgata tcagttagga aaaaaaataa tattttagat
    24241 tcgagagaaa gaagaaaaaa aatattaata aaagatatat caaaaattgt aagtgaaaat
    24301 cctcaaatgt ctgaaagaaa aataactgaa atattaatag aaaatggata taatatatcg
    24361 agaagtgcag tttcaaaatt attaaaagag gaaaatttaa atcagtcaaa gattgggatt
    24421 aaggataaag acccagcatc atcaggaaag tatgtgaagg tgagtaaagt tgtagaagaa
    24481 gatggatttg aagaattgat aggtataaag ggaagtttga aagaaaaggt aaatctagct
    24541 aagtcagcaa taatgtatcc tcctaatggc cttcatacta taatatatgg agaaacagga
    24601 gtaggtaaaa gtgaattagc tacatgtatg tataaatatg ctataaaaaa caacattaaa
    24661 gaagagaaca gcccatttat agtgtttaac tgtgcagact atgcagaaaa tcctaatcta
    24721 ttgatagctc aactctttgg ggtagtaaaa ggtgcatata caggagcaga tgcaaataga
    24781 gaaggtcttg tagaacaagc taataatgga atattgtttt tagatgaaat tcatagattg
    24841 cctgctgctg ggcaagaaat cttattttca ttaatagata gaggagaatt tagaaggtta
    24901 ggagaaagta gttctaatag aaaggcaaat gttctcataa taagtgctac aacagaaaat
    24961 ccagattcta atttacttca aacatttaga agacgtatac caatggtaat aaatttacct
    25021 aatatgagtg aaagaccaaa atctgaaaga tatgaaataa taataaagtt ttttgaaaga
    25081 gaagcaaagc gagtaaacaa gaattttata ataactaaag aagttatgtg tgcacttatg
    25141 aattataagt gtactggaaa tataggtcag ttaaagagtg atatacaagt aacttgtgct
    25201 agagctttta gtaaatcgat attttctagc gataaggtaa ttatagattt agatagttta
    25261 agggattata taaaaagtgg atattatgat tgtaattgta aaaatgaaaa gtattctgag
    25321 ttttcagttg aggatatata tatagatatt agtgaattgg tgagtggaaa aaatagaatt
    25381 ttatctgata atgagataag cgagatatat aattatgcag aaaaagagct taaggttttg
    25441 gaaagtaagt gcttttcaga agaagagtta aaaaatgcat ttatagaaaa gttagataag
    25501 aagtttaatg ctattaaaaa caataaaaat ttatctgata gaagaagtcg aatagactgg
    25561 ggaggacaat taaaagagtc tacactggag ataatggata aggtaattgt atttattaag
    25621 gagcagttta agcatgtaaa tcaaggtctg tacttggctc tagcaattca tattgagcat
    25681 gctataggta ggataaaaga tggaaaaact ataataaatc cgagtttaga taaaataaaa
    25741 gcatcaatgc caatggaata tgagttgtca agatatataa tgggtatagt agaagatttg
    25801 acacaagtaa catttccaga agatgagctt ggatatttgg cttattatat aaataaattt
    25861 tgttataatg aggaaagtat aaaagataaa gttaaagtag taatagttac gcatggtaaa
    25921 gttggaattg aaatgtctaa agttgtaaat catattttag gtatagaatg tacactaggt
    25981 atagaaatag cacttacaga ttcaccatca gaggggatag agcatgtatt agaagaactt
    26041 caaaagatag aagctagaaa aggtattcta gttctaattg atatgggttc tttggtaatt
    26101 cttggtgatg aggttgaaaa aaggcttgga attagatgta aaactgtaaa tagagtagat
    26161 acattattgg caatggaagc aggaaaactt gcaaccattg aagggaaaag tttagatggt
    26221 ataatagctg atttaaagaa aaataagaat tatgctatga taaatacaaa taaatttagt
    26281 tacagaaaaa acgagtatgg aaagaaaaat gtaatcatta ctttatgttt gagtggtgta
    26341 ggtacagctt taaatttaaa agagcatata gaaaaacaaa ttaaggaata tgacacttta
    26401 attgaagtaa agccagttgc ttttttaaat aataatttag aagaagagtt aaatgatatt
    26461 gaatctgaat ataatattat tgctatctgt ggaactattg atatagatta taaaaacgtg
    26521 ccttttattt cttataatga ggtacttggt aaaaatggta ttaataaagt attagagcat
    26581 ttaaatagta aacaaccagc tttaaatatt gaaaaccagt tgaataattt aatacatgaa
    26641 gatttgattt tatacaattt tgaaggaatt tcaaaggagt atataattga tactcttgtt
    26701 tcaaaacttg aagaaggtgg atatgttgac tcaaagtata tattaagtgt atataaaaga
    26761 gaagcaatgg gaagtgttgt aatggcctct aaggtagccg tgccacatgg acttccagaa
    26821 aacgttataa agcctgcaat agcaatcgcg aggttgaata aacctatagt atgggacaat
    26881 aaatttatgg tggatttggt ggtactactg gcacttaaag aaaataataa gaaagaaata
    26941 cgaagcttat tttcaaagat taatgaccag catactttag aagttttatt aaatactgaa
    27001 gataaaaatg aaataaaaga acttttaagc taattattag taccgagaag aaagacaaaa
    27061 aaatttgctt tagtataaaa tttaaaacta ctcaattgtt aagtagttaa ttactctata
    27121 taaggctagt tctatgaaat ttatttatat gattttatag aattagcttt tttcttggta
    27181 aataaaatat atgaatttat ttatgtaaaa agtaaatttt attggacaat tctatgagaa
    27241 tttttcctat atttcttata aaatatagaa tatataaaaa taaattaaat tcataataaa
    27301 taattttata aaatagttgt taaacataaa aaaccatttg taaaaaacaa aaaaatcatt
    27361 tctctaacaa aaaaaaccac aaaaaatata aaaaagtatg gctagttaag tgattaacaa
    27421 gtaaaaatta aaataaaaat caaaaaaaat ttatcaatga aagtcagcta aaatcctgga
    27481 agagagcatt atttttggga aaacattttc ttttgtttca caaaaaaagc cactttttgg
    27541 cacacaacat gctttatata aagtcaagaa aaactaaggt ataagacaaa ggcaattagg
    27601 aggtgtaaat atggagttta taaattttgt aagtgataaa gttatagacc ttaaaatgga
    27661 ttgtaaaacg aaagaagatt tctttgaaga aatacataat aaagtttttg atttaggctt
    27721 tgtaaaagaa gaatttggag aaaaaatatt agcaagagaa aatgtatttc caacaggttt
    27781 aaatttagga gattatggag tagcaatacc acatacagat gcagaatata ttaaagagca
    27841 atttatatca gtctgtactt ttaatgaacc agtagtgttt agttctatgg aagaccaaga
    27901 tgaaaaagta cctgtaaatt tggctttcgt attaggactt aatcaaccac acagtcaatt
    27961 atctgtatta acagaattaa tgggaattat gcaaaataaa gagttagttg ataagttgat
    28021 gagttctact gataaagaag aagttttaaa gacactaaag tctttataaa aataaaaaag
    28081 tactaaaaat aaaaaatata aaaataaaaa ttattaggag gaaataaaaa tgaaaaaaat
    28141 attagtagca tgtggagcag gaatagcaac atcaacagta gtttgtgaca aggtagagag
    28201 attagttaag gaaaataata tacaagcaga agttatacaa tgcaaaatag ctgaatgtgc
    28261 aacaaagcaa gaaggagcag atttaatagt atcaacaact atactaccaa caacttataa
    28321 tataccagca ataaaagcaa cagcatatat aactggagta aatacagcag cattagataa
    28381 aaaaatatta gatgctttaa aataatccta tcatagatac attgaaataa tattttataa
    28441 aacagaaaaa ggaggattta taaatggata aattattagc agtagtacaa tacattttaa
    28501 atatgggacc gacagtaata ctaccaataa caattgtagt actaggaatg atatttagaa
    28561 ttaagtttac aaaagcttta aagtcaggtc ttacaattgg tataggattt gtgggtataa
    28621 acttagttgt aaacctatta acatcaacac tagggccagc ggctcaagga atggttgaaa
    28681 gattcggact taatttaaca gtaatagatg ttggttggcc aacaacagca tcagcaacat
    28741 gggcttcacc agttgcacca atattaatac cagtttgttt attagtaaac ttactattat
    28801 tatacttcaa taaaacaaag atattaaacg ttgatatatg gaattattgg cactttatag
    28861 tagcaggtgc agttggatat atagtaacag gaagttatgt ttgggctata ttctgtgcaa
    28921 tactaatgga gttattagta ctgtttattg cagaaaagac agcaaaaaat gttcaggagt
    28981 tttatgattt agaaggtata gcattaccaa ctggttcaac agcttcattt gctccacttg
    29041 gatatttagt aggtaaattt gttgaaaaaa taccaggaat aaataaaata caagcagacc
    29101 cagactctat acaaaaaaga tttggtatat ttggagaacc aatgatgatg gggattatac
    29161 taggtataat acttggagca cttgcgggat atgatgtagc aggaatattc aatgtaggta
    29221 tatcaatggg tgcagtaatg ttacttatgc ctagaatggt tagaatatta atggaaggtt
    29281 taattccaat ttcagaatca ataagagatt tcttacaagc aaaatatgga gacagagaac
    29341 tttatatagg tctggatgca gcagtagcaa ctggacatcc agcagttata tcaacagctc
    29401 ttatacttgt tcctataact ttgttcttag cagttatact accaggaaac aaagttttac
    29461 catttggaga cttagcgaca ataccatttt atatggcatt tatagtgtgt tttagaaaag
    29521 gtaatatagt tcaatcagtt ataacaggaa caatagtaat agctatatca ctttatatgg
    29581 ctacaaactt tgcagatgtt catacacaat tattacaaca agcaaatatg atgccagaag
    29641 gaacaacaat ggttacaagt atagatacag gtggaaactt gctaaaatgg ggaatattga
    29701 aattatctca attagtttct tcatttggaa tattctagta tgtagttaat agagattact
    29761 cttttttagt aaagtatgcg aaaatttaac atttagcagc tactaaaaaa gagtaatatt
    29821 ttttataaat ttttaaaaat acaaaataca agaggaggag atttatcgtg aaagcagcag
    29881 tattacatgg cacaaatgat atgagatttg aagatataga aataaaacca tgtgaaagtg
    29941 atgaagtaaa aataaaagtt atggcagcag gaatatgtgg gtcagatcct ccaagagtat
    30001 taaaacattg gaaatatcca gttccagcta taccaggaca tgagttttct ggagtaattg
    30061 ctgaagttgg taaggatgta aaaaatgtaa aagttggaga tagagtagtt gcaattcctt
    30121 ttataccttg taatgaatgt gaatattgta aaagaggatt attttcattg tgtgataacc
    30181 atggaatgtt aggagctaaa agttttggag cttttgcaga gtatgtaaat ataaaagcta
    30241 caaatgtact tccaatagga gatatgaact ttgaagatgc tgcaatgata gagccactag
    30301 cagttgctat gcatggagta cttaatatag gtgttcaagt tggagacact gtagctgtaa
    30361 tgggtagtgg aacaatgggg cagttggtaa tacaaggact taaaatagca ggggcaggaa
    30421 caattatagc agttgatata tctgataata aattaagaga atcaaaggaa ttaggggctg
    30481 atataataat taatgctaaa gatattaacc cagtagaaaa aataaaagaa cttactggtg
    30541 gaaaaggtgt tgacatagct cttgaatgtg caggttcaaa aataactcaa gaacaatgtt
    30601 tacttataac taaaaagaaa agtaagatag gatttttagg gatagcatat tcagatataa
    30661 ctttatcaga agaagcattt gaaaatatat ttagaaaaga actagaatta aaaggttttt
    30721 ggaactctta ttctgcacca tttccaggac aagaatggac taagggaatc aatctagtta
    30781 atgaaggaaa gataaaatta aaagaaatgg tatctcatag attctcactt gaagatactt
    30841 acaaagcatt tgaaatgata agagatagaa aagaagaatt taacaaaata ttaattttac
    30901 cacaaggggt tgaaaaataa tgaaagcagt agttaaaact aaaccaggct atgataatgt
    30961 agaagtttta gaagtagaag aaccaaaagc tacaggagac aaggttaaaa taaaagtaga
    31021 atatagtggt atatgtggtt cagatataca ttcatttaaa ggtgaatatg caaatataaa
    31081 agccccagta acattaggtc atgaattttc tggaattgtt gtagaagtag gagaagatgt
    31141 taaaaatata aaagtaggag atagagttac atcagagact acttttgcaa cttgtgagaa
    31201 atgtatatat tgtgaaacta aagattataa cttatgccca actagaaaag gtattggtac
    31261 tcaagtaaat ggaagttttg ctgagtatgt attatcaaga gaagaaagca tacatgtact
    31321 tcctgaaaat gtatctttat tatcagcagc ccttacagag ccactagctt gttgtgttca
    31381 tgcagctctt gaaaagacta ctatagaaag ttctgataca gttttaataa taggaccagg
    31441 accaattggt ttattattag ctcaagttgt taaatctcaa ggtgctacag ttataatgtc
    31501 tggtgttaca aaagataagg aaagattaga aatagctaaa aatcttggag tagatagaac
    31561 tgtaaatgta atgaaagaaa gtttggcaga tgtagtgaat gaaatgactg atggaaatgg
    31621 agtaaacaaa ggatttgatt gttctgggtt tatgccagca gttaacgaag ccttaagact
    31681 gcttagaaaa aaaggtactt tcgtacaagt tggaatcttt gctaaaaaat taaatgaaat
    31741 ggaccaagaa gcaataatcc aaagagagtt acaatatata ggaagcaggt ctcaaaagcc
    31801 aagttcttgg attacagcat tagatttaat ggcaaatggg aaagtaaata cagaagcttt
    31861 agttactaga actgttggtt tagacgaatt taaagaaggt attacagctt taatgaacgg
    31921 ggaagaaata aaagtagcag taaaatctta aaaaaacatt tgtattattt taaaaaaaat
    31981 tgtaaaatct actgtaggat aaaaaaatgt aaggtcttaa aaaataacag gaggaagaaa
    32041 gtatgagcac tcttagagat cattctaata atattagaaa aaacataata aaaatggttg
    32101 cagaagctaa aagcggacat ccaggtggtt cattatcaat agctgatatg ttgacagtat
    32161 tatattttga taagatgaac gtatgtgcag aaaatccaaa aatggctgat agagatagat
    32221 ttgttctatc aaaaggtcat gcagcaccag ctttatatgc tacattagca gaaaaaggat
    32281 ttttcccaga agaagaatta ataacactaa gaaaatttgg ttctaagtta caaggtcatc
    32341 cagacatgaa aaaagtagca ggaatcgata tgtctactgg ttctcttggt caagggctat
    32401 ctgcagcaaa tggtatggca cttgcaggaa aattagataa caaagactat acagtatata
    32461 ctatattagg tgatggagaa atccaagaag gtcaaatatg ggaagctgca atgacagcat
    32521 cacattacaa attagataat ttaattgcat ttgttgactt aaatggatta caaatagatg
    32581 gttctaatga agaagtaatg aatgtaaatc cagtagatga caaattcaaa tcttttggat
    32641 ggaatgtaat agtaataaat ggacattctt ttgaagaaat aggaaatgca gttgatgaag
    32701 ctaaaaaagt tacaggaaaa ccaactgtaa taatagctaa aacagtaaaa ggtaaaggtg
    32761 tttcatttat ggaaaataat gctgcatggc atggaacagc tccaaatgca gaacaagcag
    32821 agcaagcatt gaaagattta gaaggaggtc tataggaatg ggaatagcaa ctagagaagc
    32881 ttacggacaa gtgttaaaag aacttgcaga aaataaagat atagtagtat tagatgcaga
    32941 tttaggaaaa gctacaaaaa gtatatcatt taaagaagtt gccccagata gattttttga
    33001 catggggata gcagaaggtg acatgattgg tacagcagca ggtcttgcta cttgtggaaa
    33061 aatacctttt gcgagtactt ttgcaatatt tgcagcagga agaggctatg agcaaataag
    33121 aaactctgta gcatatccaa atttaaatgt aaaaatagca gctactcatg caggtgtaac
    33181 agtaggtgaa gatggtggta gccatcaagc tatagaggat atatctctaa tgagaggtat
    33241 accaaatatg gttgtattaa atccagcaga tgctttagaa gcaagacaag ctattcttgc
    33301 atctattgat tataatggac ctgtttatat aagattaggt agagctgcaa ctcctgatgt
    33361 aaacagtgaa aattataaat ttgaaatagg aaaaggaact gttttaagag aaggttctga
    33421 cataacagta atagctacag gaataatggt agcaaaagcc ttagaagcag cagaagaact
    33481 tgctaaagaa ggtataaatg tagaagttgt taatatatct acaataaaac cattagatga
    33541 agcattaata aaagaaactg ctaagaaaac tggaaaagta gttacagcag aggagcacag
    33601 tataataggt ggtttaggtt cagctgtatg tgaagcttta gcagaaacta aagatgtagt
    33661 agttagaaga attggtgtta aagatgtatt tggtcaatca ggtacaccag ctgatttatt
    33721 aaaacactat ggtttaacta cagaagatat agtaaaaaat ataaaagagt tattatagat
    33781 ataaatatat ctaaataaca aattgatttg acataagtca attaaagctg tcttaaaaat
    33841 agaaagaaat ttctacaatg ggacagcttt atttttacaa tactttattt ttatgataat
    33901 tataaaatag tctgaaagta atcaaaaaaa ttataaaaag aggtgctatt taatgaaaat
    33961 atctattgga tgtgaccatg gtggttatga attaaaggaa tatataaagg aaaatttaat
    34021 aaataaaggt atagaagttg aagatgtggg tacaaattca aaagaaagtg tagattttcc
    34081 aatatatgca aaaaaggtaa gtcaaaatgt tcaaagtaaa aaatctgatt taggcatact
    34141 ttgttgtgga acaggaatag gtatgtctat tgcagcaaat aagtttaaag gaatcagagc
    34201 agctgttgtt tctgactgtt tttcagctaa ggcaactaga gaacacaata atacaaatgt
    34261 actttgttta ggagaaagag ttattgggaa aggattagca atgagaattg ttgaagaatg
    34321 gttaaattca agttataatg gagaaagaca tgcaagaaga ttacaaatga ttgatgatat
    34381 agaaaaagaa aatttataaa tatataattt ataacaaggg ggagcgttat gtctattatt
    34441 tgtgcttcaa taatgtgtgc agaccaaatg aagttaaaag aggaattaga agctcttgaa
    34501 gaagcaggtg taaaattact tcattgtgat gttatggatg gaatatttgt taaaaacttg
    34561 gctatgggac cagagttatt aaaatcaata agtgaaaata caacaatacc tttagacata
    34621 cacttagcca cagaaactcc agataaatat attgatatga tgtcttatat aaagccaaaa
    34681 tatatttctt ttcatgtaga atcaagtaca aatgtaaaag ctgatataca aaagttaaga
    34741 aattatggta tagggccagt gttagcaata agccctcaaa caagtgtgga taaaatagaa
    34801 gaatatataa gtttagttga gggtatctta gtaatgacag taaatccagg gtttgcaggt
    34861 caaaagttta atctttctgt attggataag ttggataaac ttacagagat actaaaagat
    34921 tatgataatc ctccatttat agaggttgat ggaaatataa ataaggatac tattaaactt
    34981 atgaatggta aaaaagtaga tatatatgtt gttggtactt cagctttatt taatgataag
    35041 cctccaattt catataaaga taaaatagaa gaactaaaag aaagtataaa gtaaccatgt
    35101 aataaaatta taatatgttt ctgtttaata gtaaaaattt aggtggaaac aagaaatttt
    35161 ataatattta ataaaaattt tggttgagta aggagaattt tttatgggag acctatataa
    35221 actacaaaat ggtactgata ttagaggaat agcgtatgaa aatgattcta aagaagttaa
    35281 cctaactgta gaagaagtaa aaaaaatagc taaagcgttt catatttggt taaaagaaaa
    35341 gactaagaaa gataaagtaa ctgttgccat aggaactgat tctaggataa caggaagcca
    35401 atttagaagt actgttattg aaactttaac taatgatgat tgtaatgtaa ttgattgtga
    35461 gattgccaca actccagcta tgtttatgac aactattatg gatggataca attctgatgg
    35521 ggcgattatg attacagcaa gtcacttacc ttattactat aatggtttaa agtttttcac
    35581 agaaagtgga ggtttagaaa aaactgatat aaaagagatg ttggatatag ctgttaaaaa
    35641 tgatagtgta gactatgagg aagtaaataa aaaaggtgaa gttatagtaa aaaatttaat
    35701 agaagattat tctaatttat tgatagataa aattagaaaa ggtgtaaatt caagtaaaaa
    35761 ttatgaaaag cctttttctg ggcttaagat attggttgat gcaggaaatg gggctggtgg
    35821 attctttgct gaaaaagttt tacacatact gggagcagat acgacaggta gtcagttttt
    35881 gaacccagat ggtatgttcc caaatcatat acctaatccc gaaaacaaag aagcaatgga
    35941 aagcatatgt aaagctgtgt tggataataa gagcgaccta ggaataatct ttgatacaga
    36001 tgtagacaga gctgctattg taggtaaaaa tggcaaacca ataaataaaa atgctcttat
    36061 agctgttata tcatcaatag tattagaaga acatccaaaa acagctatag taacagattc
    36121 gattacttct gaaggacttg ctaaatttat aaatgaatta caaggaagac atcatagatt
    36181 taaaagagga tataaaaatg taataaatga agctataaga ttaaatagtg aaggtgaaga
    36241 gtgccattta gctatagaaa cgtctggaca tgctgcttta aaagaaaatt atttcttaga
    36301 tgatggggca tatttaatag ctaaaatttt aataaaagta gcaaagctat ccttggaagg
    36361 aaagactata gaagaattga tagaaaacct tgaagaagct caagaagaga aagaagttag
    36421 aataggcatt aataaagaag attttagaac atatgcagag gatatattaa aagatttaga
    36481 ttctcatgtt aagagtattg atggatggtc tgtagcacca aataattttg aaggcataag
    36541 agttaattgt gatgaatcaa atggagatgg atggttttta cttagaatat cactacatga
    36601 accattatta gctttaaata ttgaatcaaa taaaattggc ggagcagaac aaatttattc
    36661 taagttaaaa cttttcttag aaaaatatga tttaaaaggt ctttagggta aatagaaaga
    36721 atatatttat attgaagaat aaatgtaaat ttgtacctaa gattacaaat attacaaaat
    36781 tgtaatctta ggtaacagag atgtaactga ttatggaaac actatgtgat attatagata
    36841 cagagagatg aaatatgtga tgaattatag agaaatataa tttaaaatgt attaatatca
    36901 caccaaaaag gtataatcaa aaaatatgta aatataaacc ccaacattta gaaaaagacc
    36961 tctaaggagg tttttttctt gtttaaataa cttaaaatat atttttatat taatatatca
    37021 attaactctt ctaaaagtaa gcattacctt aaataaatca gcatctataa ttatttccat
    37081 gtgtgcattt tctaattcaa ttatattttg agcaattgat aaaccaagac cagagccatc
    37141 tgtttttcta gatatatcac cccttctaaa tctttctatt aactcttctg gttttagatt
    37201 tagtttatca tttgaaatat ttttaaacgt taatattata ttttcttcct ttataaacat
    37261 atctatatag accctagtgt taggcataga gtattttagt atattgcaaa ttagattctc
    37321 aaaaactctc caagtttttt taccatctat catggtaaaa acagcatatt caggtgtttc
    37381 tattataaaa tctaaactgc tattttgaat tttgtcttca aattctacaa tactttgaat
    37441 taaaagttct cttatatcgg tttttgttat attaaattct acatctccac tacttagctt
    37501 agatgcttca aatatgtcat ctattaataa ttttaatctt tgtgattttt tatctaaaat
    37561 atttatatag tcatttatag tctctctgtc aaagtcatta ttttttaaca tatcaacata
    37621 gcttaatata gatgtaagtg gagtttttaa gtcatgagat acgtttgtga taagctctgc
    37681 cttcatcctt tcatttttta tattagcatc tacagcagtt tcaagaccgc ctgttatatt
    37741 atttatactt ttggctaaag tagatatttc atcatctcct ataacttcta atttatactt
    37801 taaattgcca ttttctatat tttttatatt ttttgatatg ttatttatgt aattaaactt
    37861 aacagataaa aagttgtata tataaaaatg aaaaactgtg tttacaagtg taaataaaat
    37921 tactatagct attgcctcag cataatatat atacataaag aatatcaaaa caagatattg
    37981 gataatagct tgtacaacta tagatattaa aaatactata gctaattttt tatttatagt
    38041 ttttttatta tacatactaa gtaagtttga aaagaataca tatgttatag acatatcttt
    38101 tagattatag ttattatatt taatattttc atatattata tagactatag atataattat
    38161 aaaattgtag attattaaat tagtgttgta aaacatttta ttacttgtaa atgcatgaaa
    38221 ccttaaggtt aatagtatca aagttaatat aagtgtaagt tctattttta ccttagaaaa
    38281 aaggtttatg acattctcta agaatttgac tttagtttgt ttattttttt tatacaatgt
    38341 aaaacatagt atagtcaata aaaaacttga taatataata cctatgcaga caaactctaa
    38401 ttctactttt gacaaatgta caggagtacc gaaaaaataa aaatgaggga gagcaaactc
    38461 tctataataa taattaatat tagaaaagtt attattcaaa tcataaactg cttcaaataa
    38521 tatagaaact aatagaaaca gtaataataa taaaataaat tttgctttag aatcattaat
    38581 aattaagttt ttcaattttg taaccaatgc cccacaccac ctttaaatat tttggttctt
    38641 ttggattaat ttcaatcttt tctctaattc ttctaatatg aacagcaata gttctctcac
    38701 aactataagc atcctcattc cagacatttt cataaatctc atgagaagag aaaattttac
    38761 cttttcgtga cataagaagt gtaagtattt tatattcaag tggtgtcatt ttaatttcct
    38821 caccatctaa agaaactatt tttgtatctg tatttagctc taggccacca ctttttagaa
    38881 tataattagt atcatttgag ttatttgtat tactaaaatc acctaaattt atataccttc
    38941 taagttgaga ttttactcga gcagtaagtt ctagtggatt aaatggttta gttatatagt
    39001 catcagcacc catattaaga cctataattt tgtccatatc ttctgatttt gcagataaga
    39061 gaattattgg tatattcctt ttttctctta ttttaagtgt agttttaagc ccatctaaat
    39121 tgggcatcat tacatccatt attattaatt taatatcatt ttcgattagt atgtccaatg
    39181 cttcaagtcc atcatatgcc tttaaaacat taaagttatc aggtctcaaa tagaactcta
    39241 tagcatcaac tatctctcta tcatcatcta caaccaatat attttgattc aatttattaa
    39301 cccccttgaa attttatttt taaccaattt ttattttata ccaaaaagag gtattagaaa
    39361 acagtaagcc cgttcattat gaaataaaaa ctagtacttt taatatattg tcaatgcata
    39421 tagtaaattt aaaagtatag acgcccatat taatctgaag gtaaaagttt atgaaaatat
    39481 ctagggtaat ctatcacact tcttatgtta ttttggttta ttaatttttt aggtttaaac
    39541 atatattaac aaatataaat aacaaatgag tttcataatt attaagaatt tataacaaat
    39601 atttatttta atgtagttta atataaacag gtagtttaat gtaggtatgt ataaagcatt
    39661 taataaggct tataggtttt aatgatgata tctttatata ttttaagaga tgatgaaatt
    39721 agatatgggt aatagttgta tgagaaaaag tagtatagca caaaaagtgc tatatcacaa
    39781 aatctcaaat aatttccttt ttataactta aattaaagaa taaatatttc ttataaatta
    39841 ggtgtatgaa gtatagcagg aacatcttta ttatttaata acttatcaaa tgatttatgg
    39901 tcagacttat agccaatacc ttctctatat tctaattcat caacaatttt gtattgttga
    39961 caggcatttt taaccttttc atagtcctca gtagaatgag ctttataaac tatcttatta
    40021 ttaaaagtta ttttatcagc aaatttaggt tttacaaaat atttagcatc ttttatttta
    40081 ccagcattat ataaattttg gataacagaa ccatttttta aatgttgtaa atggtcatct
    40141 aatttataag tatgtgctat atgagttaca tttttaaatt tttcttcaaa tgtaagagca
    40201 attttttcca tgtaattgaa gtcagtatta ccatttgtat ttgtttctgg taataatatt
    40261 atattttccc ttattacacc aaggctatta agagaagcta aaaattctct atttctatat
    40321 tctgattttt gtatatttgt taggttttca tattttttat atttatcaaa gacggatata
    40381 ccacatccag tagatactaa aaccacaaat acatgatttt ttcctctttc ttttatagca
    40441 ttaacaatag cactcccagc ccacaacact tcatcatctt gatgctgaac atagaagaca
    40501 acataatctt taaatttttt atgactataa ttcacatagc tactaaaagc ggttaaaatc
    40561 aaacataaaa ctagaataat agatagaatt ttatatttat ttatagtaaa ttttttattc
    40621 ttaaatgtca tttaatcatc tcctgaaagg ttgtcttagt tatattatca aacaaagtac
    40681 taaaaattat ttcttaaatg ctgaaaaata tagagtagat taatggaata aaattttttt
    40741 attagtttaa aataaagaaa acatttatgt ataagactaa tcaaaatatt aatgattgat
    40801 aggaattgag atttaaaggg attgtacatt tattcgggat tcattttaat agaattttac
    40861 tttagtactt agaataaaag taataacttt ttaaatttaa agagtacaca tatatatttg
    40921 tgtactcctt gatgatatga ttgcttattt actacaaaaa cagagtcttt ttaaacctaa
    40981 aatatttgat gcaccagcta tcgtagttcc ataatagtaa actggtttgt taagtgatag
    41041 aaaatttata attgagttat tacataatgt acttcctgtg caaatcacta aatcagccca
    41101 agatattaca tcttcataat ctcgtatacc atcttcaatc ttaacattat attgaatagt
    41161 atccacaaat tcaggattta aatctaatac tcttgtttcg aaaaagtcct taatattatc
    41221 aattatggct ggttgatatc ctataattgc tacttttgga ttaccaaatt ccatttttat
    41281 aaactcaggg aatttttttg cacatacctc tggctcgtta tttttacaat gaatggttct
    41341 atccgtcttg cctaagtatt tcataactgc atttaatgat gctataaaaa gacttctatc
    41401 atgagaattg tcatgtaaat ctaatgataa tatgtctttt aaagaacctt caaatgtaga
    41461 tggagtagaa gtaaatgctt gtcctttagc tcctttaaag tcagcttcaa gcattatttc
    41521 tttaccaact ataattggga aatctttacg cttagtattt ccaattgctt cttttgaaga
    41581 tagagatttg gacacaatac ttatcatatc catatttaaa ttatatttat cgacttgtac
    41641 taatagataa tctctcaaaa tatcaaatat attcatagaa aaaagattct cctttatttt
    41701 ttatttcttc atttaaatca aaaatatgat ttatttttcc attgttcatt attcctatct
    41761 tatgagcaaa aaacattgct tcagaaatat catgagtaac atgaatcact gttggtttgt
    41821 attttatgta gacatccttc aaaattttgc ttatatgttt ttttgtaata taatccaatg
    41881 aactcatagg ttcatctaaa agtaatatat caggttcagc tattaaggca cgtgcaaaag
    41941 caactcgttg cttttcgcct ccacttaaat ttttaggata cctatttttt atatcttcta
    42001 tctgcattaa tttagacaag tggttagcct taagaatctg ttcatctata ggtatttttc
    42061 tcaatttaag tggaaacctt atattatctt caacattcat atttggaaat aattcaaaat
    42121 tttgatatac aaatcctata tttctatttt ctggaggtaa gtttgatatt aaattttctt
    42181 tgtatgatac atttccttta gcagatggat atcttcctgc taatgtttct agaaatagag
    42241 ttttacctga cccactagct cctaataaaa caaagtattc atgattatta atatttaaac
    42301 tattttcttg taatttaaaa ttaggtaaat caagagataa attttttatt tttaacatat
    42361 taattcttat caacctctct attaaaaaat atctcaaaaa gcatcaagca tgtaagtgag
    42421 agaaatatca aaattacagc tattccgata gcaatgtcta tatcaccagt agacatattt
    42481 aaatatatag atgtaggaat aatttcagtt ttcatacgtg tagaacctgc tatcatagct
    42541 actgcaccaa attcaccaag tgctcttgac caagtcatta cagttgcaga tatgattcca
    42601 gtttttagat ttggaagaat tataaatcta aatgcttccc aactattaca tccaagggta
    42661 cgtgcaacaa atatcatctt ttcattactt tcatttaatg aagtgtgaag tattttaata
    42721 gtaagtggaa gatttacaaa tatttgtgct aaaactatac cttgctttgt aaatataaaa
    42781 tcaagcttaa aaatcttata aatggaatct ccaatcccca ttcttccaaa caaaagtaaa
    42841 agagcaattc ctgatactaa gtgtggaaga gacataggga gatttattat ctgtataatc
    42901 agttttttaa atggtaattt agtaatatgt aaaaaatatg ctactggaat agctaataaa
    42961 aggcatacta tagtagatat taaagatgtt ttaatactaa gtgttattgc atactgtact
    43021 tccactgatt ttaagcatat aggaacataa cttatccctt taatgattaa cataagaagt
    43081 ggtgatacaa taaacaaaaa gactatagca aaaaatccag taagtagagt agtaaaaaat
    43141 ttatttttca agtttaatca ctacttaaca ggttcaaaac catatttttt aaatatctgt
    43201 ttagcttcgt ctgactctat ataatttata aatttattag ctaaatcttt tttatcacta
    43261 tagtttacga ttcctgctga tatgagttgg tctatatttt tatcttgggc aatttctata
    43321 acttctacat cttcattacc aaagaccgaa tcttttgtgg ctattgtagc atcagcttta
    43381 cttgatgtta actgtacaat catttcattt acagttgcag ctgtagagac aacattatca
    43441 tttatagatt ttaaattatt tttttcaagt attttttgtg tagtcttacc tatagcatta
    43501 gactctttgt ctcccaaaat aagtttaact ccatctttat ttaagtcttc caatttttga
    43561 atattagctg gatttccttt aggtacaact attgcaggtg tatgatgtgc aaccgtttta
    43621 tgttcaccta caagttcttt ttcaaaggcc tttgaataaa ttggttcaga accaacaata
    43681 aatacgtctc ctttgtgact tgtctcaatt tgagctatta gctgtgcaga acctgcatag
    43741 ctatattcaa ctttgacatt attttctttc tcaaattttt ttgctatttc atccattggt
    43801 ttctttaaac ctgcccctga atagacaaaa agagtctctt tttcttttga atcatcagct
    43861 gttgtcactt tagtattaga ttcatcatta gctttgtttt ctttagaatt acatgcagta
    43921 atacttaatg aaataatcat agctaaagct agtactgaaa gttttttaaa cataagatat
    43981 tcccccttat taaattagtg taaattcttt tttagtatat catactaaga aaacgatgtc
    44041 taagtttttg ttgtgtttta taatgttttg ttatgttttg ttatgtatag ttaagaaaaa
    44101 atctattcat aatgtcattt ccataggtag ttattttatt tttaattttt attaatactt
    44161 taaagtattt taaatttaaa aacttaa
//
LOCUS       DAMJXI010000029        43079 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.030, whole genome shotgun sequence.
ACCESSION   DAMJXI010000029 DAMJXI010000000
VERSION     DAMJXI010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 43079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43079
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.030"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            156..497
                     /locus_tag="PC465_002023"
     CDS             156..497
                     /locus_tag="PC465_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator"
                     /protein_id="HDF2649318.1"
                     /translation="MKEENFINVEYEDKRFSINSKEVLYIEKQEYEVKIYTESGNYEV
                     GENAPCIRKLLKEENFFKCSNSYIVNLDKCEFYLSNNCIFVNNNFIRILGSERKKKLK
                     KKLEKLYDYED"
     gene            648..1061
                     /locus_tag="PC465_002024"
     CDS             648..1061
                     /locus_tag="PC465_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HDF2649319.1"
                     /translation="MIELKNNLGISERKLKYPCIYKHFKGKYYATMGLSKAIDDIENI
                     CEIYGKENLIQNRNKYKLVIRHTEREEDIYVYRDLDGNFYHKKEEDTNDLVLYKTLYD
                     DTGIFARPLDMFLEKVDTDKYVNSIQEYRFEEVYK"
     gene            1263..1904
                     /locus_tag="PC465_002025"
     CDS             1263..1904
                     /locus_tag="PC465_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDF2649320.1"
                     /translation="MGNTFYIVRHGQTDWNILGKTQGHGNSDLTPQGIEQAKELSEDI
                     GKYSIDYIFSSDLGRAMQTAQILGDKLNIEVQKTEALREMGFGVWEGLLIKEIQKDYS
                     DIYATWRNEPHLVNIPEGETLKIIKERVDAFIKELNEKYDNKNIILVTHSITLRVMLL
                     SFLESGMENIYRIKQDNTALNIVEFKDYGPVIVKMNDTSHIKNHVKINNSALE"
     gene            1928..3181
                     /locus_tag="PC465_002026"
     CDS             1928..3181
                     /locus_tag="PC465_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2649321.1"
                     /translation="MSKVIVVGGGASGMMAALSASKNNNEVILVERNGELGRKLRATG
                     GGRCNFTNNREIEDFFDKVVSNKKFLYSSFYTFTNKDLISYFESRNLEYKIEEENDHK
                     VYTKNDKSIEVIEVLNKDLLNHNVKIMYNKKVIDIITEEIALKDDSNKDKSKYLIKGI
                     ILDNGDKILGDKVIISTGGVSYSKTGSDGSMYKILKKHGHTLNKLYPALVPLTIEEKW
                     IKDLQGISMKNVEISCKIKKRKISKSGDMLFAHFGITGPCVLIMSSYINKIIEKEKVE
                     LNIDFLPNLSTDEISSIIRAFPNKNVLNNLKQILPQNFLKEIFSLLSLVDKKASDLSK
                     ADEIRIIEYIKNMKLTCNGTTGINTGMVTSGGISVKEINSSTMESKLVKNLFFTGEVI
                     DIDAETGGYNLQIAFSTGYLAGISV"
     gene            3227..3877
                     /locus_tag="PC465_002027"
     CDS             3227..3877
                     /locus_tag="PC465_002027"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HDF2649322.1"
                     /translation="MGNLVIAVDGPAGAGKSTIAKIVAKKLNINYIDTGAMYRAVTYK
                     CLKSGIDVNNAKEVIQIAENSDIDFKDNNIYLDNEVINEEIRTIEVSNNVSNVAKIKE
                     VRQLMVEVQRKIGMKSSVILDGRDIGSYVFPDADYKFFLVATPEERGNRRYKELCNKG
                     YNTTLEEVIEDIIRRDEIDSNREFAPLVKANDALEIDTTGKTIEEVVEEVVSKINL"
     gene            3928..4524
                     /locus_tag="PC465_002028"
     CDS             3928..4524
                     /locus_tag="PC465_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HDF2649323.1"
                     /translation="MNFYRFVINIFKGFSKIFFKYEVIGAENIPDRGNIVIASNHKSN
                     LDPIFLAAAIENREIAAIAKKELFKVKPLGFILKKLHVMPINREKPDVSTIKTILRSV
                     RDGYVLGIFPEGTRIKGDSFGKAKAGLSVFTIKSKSKVVPVSIISKYKLFSKVIVYIG
                     EPISFEEHFKEKLSNDDHERISQEILEVIKQNYFKYSK"
     gene            4537..5376
                     /locus_tag="PC465_002029"
     CDS             4537..5376
                     /locus_tag="PC465_002029"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HDF2649324.1"
                     /translation="MNIKIAKNAGFCFGVKRAMKMAWDEVEKNDSGIYALGPLIHNKQ
                     AVAKYEEKGLKTVNEIDTIPNHENMIIRSHGVPENIYKEAKDKKLKIVDTTCPFVKKI
                     HTVVSEYHNKGYEIIVIGDMKHPEVIGINGWCENSAIIIKTLEQMENMEFDNSKRYCL
                     VAQTTINPELYISIVNKLSDKLEEIVFNDTICSATKTRQESAKELAKEVDCMIVIGGK
                     HSSNTQKLVKVCEDLVPTFAIETKDELDVNTLKKYKNLGITAGASTPNWIIEEVVTFL
                     ENL"
     gene            5621..6775
                     /locus_tag="PC465_002030"
     CDS             5621..6775
                     /locus_tag="PC465_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic efflux protein"
                     /protein_id="HDF2649325.1"
                     /translation="MEMLISASEEAFLHVGSMIGFFILLFGYINYKTSGNFTNIISKN
                     RKFQPLIGALIGAIPGCGGSLAIMPLYINGKLSFGAIIASLIASMGDAAFVLISSNIK
                     MYFFVTIVSTITGIITGQLVDYFKLEEKLGLKNRRKSDKYDISKNNSKENKEQHNHDE
                     IILDTLAKSHGNTNRLAFIITHGKGYKIYIGIIVIGFIFMSLAHSGLNLPIIEKLHSL
                     EEVIAVIGILFSIIYMWCFKKVFKNSNQKEEENKKISLREMLIHSVGEISFVITWIFI
                     AYLIYDLIILILGGDEYLVKLVLSTGVISVFIGAGLGLIPGCGIQIVLMSFYLKGTIP
                     LGAVIANSISQDGDALFPLLAMDKKSSLWAMIITTIPAILVGMIVYAFLG"
     gene            7081..8778
                     /gene="ade"
                     /locus_tag="PC465_002031"
     CDS             7081..8778
                     /gene="ade"
                     /locus_tag="PC465_002031"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HDF2649326.1"
                     /translation="MGNLKRQCDVSSGREKADIVLKNGTIINVFTEELITGDVAIVGD
                     TIVGIGDYKGNVEIDCSNKYISPGFIDAHMHIESTMVMPIELSKKLLKSGTTTIIADP
                     HELVNVKGASAIDFLLESTKDIPLNVYIMVPSSVPATSFETNGVGKFSAKDMESYVNN
                     PRILGLGEVMCFNDVINSENEILDKLELFKNKVVDGHAPNINGKSLQTYVCAGIENDH
                     ECITFDEVYEKLRAGLKILIREGSAAKNLKSIVSGMLKHNLPIEEFMFCTDDKHLDDI
                     EKQGHIRWNIKCAIDLGMEPVRAIKVATYNSAKAYGLRKIGAIGAGYKADIVVLNDLD
                     KMEVDSVYKDGNLVNEEMFSNYNYEIKDKELLNTVKFKYINKEKIQLKVSEKNYVMEI
                     VPYQILTNKVYESLPCADGYFVPNKEYSKLCVVERHRMTGNVAIAPLKGFGIKNGAIA
                     TTVAHDSHNIIVAGDNDDDILVAINYLKEIQGGYVIVSNGKVLAHLSLQVAGLISTFT
                     AEEVQEITDNMLEIARKMGVPEYVDPFITLSFMALPVVPQIRLTDLGLFDVEEFKFI"
     gene            9130..9594
                     /gene="bcp"
                     /locus_tag="PC465_002032"
     CDS             9130..9594
                     /gene="bcp"
                     /locus_tag="PC465_002032"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HDF2649327.1"
                     /translation="MLSIGTKAPEFTLEDKDGNKVSMSDFKGKKVVVYFYPKDNTPGC
                     TRQACAFRNAYDGFKKEDIQVIGISKDSIKSHQKFAEKHELPFILLSDPDLVAIKAFD
                     VWKEKKMYGKTALGVVRATYIIDENGIIEKVFEKAKPDTNAQEILEYLEKQE"
     gene            9604..10347
                     /gene="yaaA"
                     /locus_tag="PC465_002033"
     CDS             9604..10347
                     /gene="yaaA"
                     /locus_tag="PC465_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HDF2649328.1"
                     /translation="MIIMLSPAKNMKNIEVFDRDLSLPCFIDNTKEIVENIKTFGIED
                     FKNKMKINEKLAVLNKNRFESIKFDRLGNPAILTYDGIQYKNIEAENFTRKDEEFANS
                     CIRIISGLYGVVKPYDSIYEYRLEMQTKLQVGEFKNLYEYWGNRIYKELIKEKTAIVN
                     LSSNEYSKSIEKFIKDSDTYITCTFKVNKNGILKVESTQAKKARGMMTKYIVKNRIRD
                     IEELKKFDLEGYKYKENLSNNSEYIFVKE"
     gene            10475..13132
                     /locus_tag="PC465_002034"
     CDS             10475..13132
                     /locus_tag="PC465_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDF2649329.1"
                     /translation="MENHKQMPWHSRATHEILESLDSSEEGLTDTEAEKRLKENGLNE
                     LRKKPPRTTLQMLWSQITDAMVMILIGAAILSLIFGEFTEAFVILIIVTVNAVIGIVQ
                     EKKAESSLEALKNMNSPTARVMRDGEENVIPASNLVVGDIVFLEDGAMVPADLRLIET
                     SSLKIQEASLTGESVPSEKDADTILPKECVLGDRSNMAYTSSIVTYGRGVGVVVATGM
                     DTEVGNIAHLLDSQDDFDTPIKRKLNTVGKTLSVIGIIVCVVIFAIGAFYQRPLLPMF
                     MIAISLAISIIPEGLPATATIVMALGVQRMAKRNALIRKLPAVETLGGATVICCDKTG
                     TLTLNKMTVTHIAVNGDFESGKVTSIDTASEKHPLVYKEIVYAGALCNDACINPDKTD
                     EILGDPTEGALIFMAKKFGIDQEALEEEYPRVFEQPFDSDRKCMTTVHNIDEKIIAYT
                     KGAVDEILDLCTKILTSKGERNITEVDKKNIHELCLNMSKDALRVLGFAKREISSIPK
                     EDSENIEYDLTFIGMVGMIDPPRTEVIDAVSTCKEAGIRTIMITGDHKVTATTIAHEL
                     GIWSEENTVISGDELDNLSDDELDEAVKNTTVFARVSPFDKLRIIQSLKRIGEVPAMT
                     GDGVNDSPALKSADIGIAMGISGTDVAKDSSDMILMDDSFTTIAYAIKEGRRVYRNIQ
                     KVIQFLLVGNIAEILTLFVAILLNWDTPLLAVHILWVNLATATLPALALGVDPPSRNI
                     MKHQPVKSTTLFEKNLIQRVVTQGIFVAIMTILAYKIGLNIENHSVGQTMAFCVLAFS
                     QMLRAFSQRSNTDSMFNRNNGKNPFLLISFLTSAFLIAVILFVPVFRNAFNLTVLNNL
                     EWLITIVLAIMSVIQVEVGKIIKRKKLKK"
     regulatory      13186..13288
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            13398..14663
                     /locus_tag="PC465_002035"
     CDS             13398..14663
                     /locus_tag="PC465_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HDF2649330.1"
                     /translation="MYNKETICVQGNYKPGNGEPRVLPLYQSTTFKYSSIDQLAELFD
                     LKVDGHIYSRISNPTIQAFEEKISLLEGGVSSVAVSSGQSANMLAVLNICKSGDSILC
                     SSKVYGGTFNLLGPSLKKFGIDLISFDLDSSEDEIVELAKENTKVVFAETLANPTLEV
                     IDFEKIANVAKRINVPFIVDNSLASPVLCNPLKYGANIVTHSTTKYLDGHASSVGGII
                     VDGGNFNWDNGKFPELVEPDPTYHGISYTQKFGNAAYATKARVQLLRDYGNCLSPFNA
                     YLTNLNVETLHLRMERHSENALKIARFLEKHENVDWINYPGLEDNKYYENAKKYLSRG
                     CSGVLSFGVRGGLENAKKFVEKLQIASLVTHVSDVRTCVIHPASTTHRQLTEEQLIAS
                     GVLPSLIRLSVGIENVEDLIADLNQALNF"
     gene            14693..15583
                     /gene="metA"
                     /locus_tag="PC465_002036"
     CDS             14693..15583
                     /gene="metA"
                     /locus_tag="PC465_002036"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HDF2649331.1"
                     /translation="MALILPKGLPVINKLLDEGIDVIYKEDFKKELKYEENIDTKIAI
                     LNLMPIKIDTELDLLRRIDKTGFNVSVEFIKISTRESKRSCNEYVKEFYKTFDEAKGE
                     YFDGFIITGAPVEQMEFEEVDYWNELEEIMDYSKRKTKSTLYICWAAQASLYKYYNVK
                     KLPLSQKCFGVFKHKVDKDSKIVDGFENEFFAPHSRHTTVNIEALKENKELSIVSHSK
                     EAGPYIITNSRDVFVMGHSEYDKYTLDKEYKRDINKGDKISIPQNYYINDDPSEEPTV
                     KWKKHSELLFRNWIKNYLIQ"
     gene            16074..16517
                     /locus_tag="PC465_002037"
     CDS             16074..16517
                     /locus_tag="PC465_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2649332.1"
                     /translation="MDEMSFKKELLELTRDINMKFTTLLSDFYQPLGITAVQALILSE
                     LCEHGEKKISDLGKNLNMTNSNVSVICQRLEKNGFLNRIRDIEDQRIVKVKVTNKSLD
                     IQEHISSSIFDSYFENMTSEKLQDMEDIIEGLEKLNKLLTYIDCK"
     gene            16548..18365
                     /gene="ftsH"
                     /locus_tag="PC465_002038"
     CDS             16548..18365
                     /gene="ftsH"
                     /locus_tag="PC465_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDF2649333.1"
                     /translation="MDEHKPQKRSALYYYTVIIIVVMFLNALIFPSLMDKKMVEIDYG
                     KFLTMLDTGKVKSVEIENNRIAINPSSSKDKNIYITGRMDDPELVDRLKNAKVEFTKV
                     IPKENSPLLSILLTWIIPIGILMLFGNLMMKSMQKRMGGNAMQFGKSNAKMYVSAQSG
                     KRFNDVAGQDEAKEALTEIVDFLHNPEKYKKIGAQMPKGALLVGPPGTGKTLLAKAVA
                     GEANVPFFSISGSEFVEMFVGMGASRIRDLFKQAKEKAPCIVFIDEIDTIGKKRDNGS
                     GLGGNDEREQTLNQLLSEMDGFDGGIGVVILAATNRPDSLDKALLRPGRFDRRIPVEL
                     PDLGGREAILKVHAQNVNVSSDIDYNAIARSTSGASGAELANIVNEAALLAVKSGRDI
                     VEQQDFDESVETVIAGYQRKGAVISDKEKKIIAYHEIGHALVAAMQKHSAPVHKITII
                     PRTSGALGYTMQVAEDESVLMSKEEAIDKITTFTGGRAAEEVIFNTCTSGASNDIEQA
                     TKIARAMVTRLGMSEEFDMVALETVSNQYLGGDTSLACSSDTAAKIDEEVFKIVKACH
                     KNAIEILENNIDKLHELANYLLEKETITGDEFMEILNLN"
     gene            18543..21245
                     /locus_tag="PC465_002039"
     CDS             18543..21245
                     /locus_tag="PC465_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase KdpD"
                     /protein_id="HDF2649334.1"
                     /translation="MDRPNPDILLEKIKNEEEKLSRGQLKIFFGYAAGVGKTYSMLES
                     AQNLKKVGVDVVVGYIEPHTRPETLALLDGLEILPVKEIEYKSIKLKEFDLDAALARK
                     PEVILVDEFAHSNVAGLRHTKRWQDIEELLLAGINVYTTVNVQHLESLNDIVEIITNV
                     SVKETIPDKFLDTNTQLELIDVEPDVLLERFNEGKIYKKEQATRAKNNFFIKDNLVAL
                     REIALRKTAERVNKEVQMTRLSKGDVTVIPTSDTLLACISPSPSSAKVIRTASRISDS
                     TFAKWIALYVETPNTARLPFDEQKQLQNNLKLAKKLGGEIIVLHGENIIEQILRIAKL
                     RNVTKIVIGRNHSSNKRFSKRFKKDIVDKLIDEVDYIDIHIIPYKFASDVKYKPKKDK
                     SSIKSKFKISKVDFIKLIFITLMISILAYAVQSMGFIRENILLIYMLGVVLVSMWTKG
                     YSTGIISSVFNIVLLNYFFTAPLYTLSIADSNYIVTLVVFSIVGIITSTLTSKIQHEA
                     ETAAKREENTKMIYQIIKGFLRLSNKDDIVNKGIELLSLSLSRDVICYLNVDKHNKSK
                     LYKKNTNNKDKNDLDSEDEKAVASWVLSNSTVAGNDTDTLPGSKGYYIPIVGMNLTLG
                     VVGISCIDSKLDTEDISLIETIIAQMAIALDREILSEAKENTNLEIERERLRSNLLRA
                     VSHDLRTPLAGISGAVSTIIKNKGTIGQDIIDELLSGVYEDTQWLIRLVENLLSMTKI
                     DEGKLEVKKHSELVEEIISEALQKIKKRIENALIDINIPEQILFVPMDAKLIEQVLIN
                     LIDNSLKYSKEDCKIEINVYEKDDYVWFEVSDNGPGISKELKKHIFDRFFTGEEGAKD
                     SRKGVGLGLSICKSIIQAHKGEIMVENNKDKGSTFKFSLPKENE"
     gene            21279..21977
                     /locus_tag="PC465_002040"
     CDS             21279..21977
                     /locus_tag="PC465_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2649335.1"
                     /translation="MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAV
                     SYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLT
                     KPFSIVELLARVRVAFRHSQVEAQQKDDVKSTFEVDKLLIDFDKRKVIVDDVEVHLTP
                     IEYNILSLLAKHHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRY
                     IITEVGVGYRLNDE"
     gene            22334..23290
                     /locus_tag="PC465_002041"
     CDS             22334..23290
                     /locus_tag="PC465_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CorA family divalent cation transporter"
                     /protein_id="HDF2649336.1"
                     /translation="MYILNLNTRETIEDFRDKFYVAENSYLILSAPKNLKLLKETLDI
                     DEITFNDCLKFDEITKLDLFDNYDFLSLNTFELRDGEAVIEEVNMYLSDNFILVVVNE
                     EHFLFEFVKNIILKNSQLEKNPVINLFKINYLILREVIKNGFESLEKVEELILQIEDE
                     MMDNINKNHVSRISDVRGLTRIIVKNTRPLLYIGDRIVKENIRYLKYSNVKKYNLENF
                     QGIDFGIDKLYNFALSTRELADKLLDIYSSRVGEKTNNLITKLTLLTAISAPLTIITG
                     IYGMNFRYMPELNWIYGYPATLFFMLCIIFVGIIIFKIKKLL"
     gene            23467..23622
                     /locus_tag="PC465_002042"
     CDS             23467..23622
                     /locus_tag="PC465_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649337.1"
                     /translation="MKGILKELTAKLYSFFYFMFWGFYFSAGYFFYKNICTSFLVRPY
                     FSDFEHK"
     gene            23752..24765
                     /gene="aroF"
                     /locus_tag="PC465_002043"
     CDS             23752..24765
                     /gene="aroF"
                     /locus_tag="PC465_002043"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HDF2649338.1"
                     /translation="MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGD
                     TSKIDAKRIEANKVVEKVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPC
                     SVETEDQIVSIAKDVKKSGAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLP
                     IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWL
                     MSAEYIMAGGNENVVLCERGIRTFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGK
                     SWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYDELISELKTIASAVG
                     REI"
     gene            24787..25851
                     /locus_tag="PC465_002044"
     CDS             24787..25851
                     /locus_tag="PC465_002044"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HDF2649339.1"
                     /translation="MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTD
                     ENIAKLYLDKVKNNLSESGFEIKSLILKSGEETKSFNTLPKIYDSLLDFKLTRKDLII
                     TLGGGVIGDLGGFAAATFLRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
                     QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYI
                     IHKCCFIKKTVVEADEKDFGDRMLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKIT
                     LESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVDAISLDKKNLGDTLKIILL
                     KDIGESIIYNTTSKFFQEVR"
     gene            25851..27164
                     /gene="aroA"
                     /locus_tag="PC465_002045"
     CDS             25851..27164
                     /gene="aroA"
                     /locus_tag="PC465_002045"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HDF2649340.1"
                     /translation="MGSLKIYPSKLSGDVKIPPSKSMAHRAVICSSLSNGKSRISNID
                     FSDDIIATIRAMTSLGAIIEKKEDILEISGIFSKEGILNRENQLNQPKLTIDCNESGS
                     TLRFLVPISLAFDGVKRFIGRGNLGKRPLDTYYEIFDRQNIKYSYKENQLDLIISGKL
                     KPDEFRVKGNISSQFITGLLFILPTLESDSKIIITTELESKGYLDLTLSTIKDFGVEI
                     INNNYKEFIIKGNQTYKARDYKVEGDYSQGAFYLSADAIGEDISILDLKEDSLQGDSE
                     VVEILSRMGMEILREGNKIKGITNGLNGTLIDASQCPDIIPVLSVVASLSIGRTTIIN
                     AGRLRIKECDRLHAINVELNKLGANIEEKEDSLIIEGVSKLNGGVEVWSHKDHRIAMT
                     LAIASCRCDKPIILKDFECVSKSYPHFFKDFKMLGGRIDEWNMGK"
     gene            27142..28221
                     /gene="aroC"
                     /locus_tag="PC465_002046"
     CDS             27142..28221
                     /gene="aroC"
                     /locus_tag="PC465_002046"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HDF2649341.1"
                     /translation="MSGIWGNNLKVSIFGESHGNAIGINIDGLPSGIELDLDNIDKEM
                     KRRAPGKNSISTSRNESDIPEILSGYFNGRTTGTPLCAIIRNSDTRSKDYGELKNLMR
                     PGHADFTGNVRYSGFNDYRGGGHFSGRITAPLVFCGAICKQILSQKGIEIGAHIKKIK
                     NIEDMSFDYVNISKQQLSNLQTLELPLLDLSKEEAMKNTIIDAKNQGDSVGGIIECAV
                     VGINVGLGNPFFDSVESTLSHLLFSVPAVKGVEFGLGFELADMYGSQSNDEMYYEGNQ
                     VKSKTNNNGGIIGGITTGMPIIFKVAIKPTPSISRQQNTVNIKDKKDDILYIKGRHDP
                     CIVQRAIPVIEAVTAIGIFDLMKGR"
     gene            28224..29420
                     /gene="pheA"
                     /locus_tag="PC465_002047"
     CDS             28224..29420
                     /gene="pheA"
                     /locus_tag="PC465_002047"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HDF2649342.1"
                     /translation="MEDLTRYRNEIDNIDKELIQLFEKRMNTVLEIARHKMKNNTTIL
                     QKDREEKVLSRAVDNLDNKAYSQETVQFFNSIMEISRGLQKRFIDNDGEQKIEFSLDS
                     SNKNFDLSNVNKYKSLKDELNKKNILVGFPGKSGSFTEEALNKFFNKKISKKQFKEFE
                     DVFIALKNKEINYGIIPIENSSTGAISETYDLLRKYGFYIVGEECIKIDQNLIGIKDT
                     KLEDIKEIYSHPQGIGQCSEFLKQNSTWKLIPFNNTATSAELVRKLQDKTKAAIASKK
                     AASIYGLEIISPCINDIANNYTRFVVISNQIHIEEESNKMSVVFSVEHEAGKLYKVLG
                     YFAKNNINMTKIESRPMKNASWRYFFYIDFECSIYNAKVYDLLELIEHNTAYFKFMGV
                     YKNKTE"
     gene            29467..30276
                     /gene="aroE"
                     /locus_tag="PC465_002048"
     CDS             29467..30276
                     /gene="aroE"
                     /locus_tag="PC465_002048"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDF2649343.1"
                     /translation="MNFFGLVGEKLSHSVSPQIHKRVFEILNIESAYKNFEISKEDIS
                     KLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILLRENMLYGYNTDY
                     FGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNS
                     KAILIDYEELKHIKGDIILNATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEF
                     LRIGNSMGKKTCDGLYMLVGQAIKSQEIWQDTKIDNSILDVIYNELKLEFL"
     gene            30288..30821
                     /locus_tag="PC465_002049"
     CDS             30288..30821
                     /locus_tag="PC465_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HDF2649344.1"
                     /translation="MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQI
                     SQKSIAELFSEGEDIFRNYETQACRELSISDKTVISTGGGVIKKDVNMEILKETGIII
                     FIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNNAVY
                     NITNAVSENFKFDFKEK"
     gene            30842..31681
                     /locus_tag="PC465_002050"
     CDS             30842..31681
                     /locus_tag="PC465_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HDF2649345.1"
                     /translation="MNIVIVGLGVIGGSFAKALKKAGYENVFGVDVDLETLKKAEKAK
                     IIKKGCTTGKELFKKADLIILSIYPRLVVDFLNKNKNFFKKGTIITDTTGIKETLIND
                     VLQIIPDDIDFIFGHPMAGREKKGIDFASEQVFNGANYIITPTGRNNIKNLELVENLI
                     LEIGFKRVKKLTSQKHDEIIAFTSQLPHVMAVALINSDEEGRDTGKFIGDSYRDLTRI
                     ANMNEDLWSELFLGNRDNLLKVIENFESEVNLVKEAIFNNDKNKLIEYFKKSSIRREA
                     LEK"
     gene            31949..33430
                     /locus_tag="PC465_002051"
     CDS             31949..33430
                     /locus_tag="PC465_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF2649346.1"
                     /translation="MKKNRLIAKNISIAFIVLFFFSVFTFFYVGNINRVLEYETNDII
                     TVTIAGWIILSFLFLGIIIYILYSKANSQKTIEKVAYTDFVTGYSNWRKFELDVTNLL
                     KKTSQNNKYAMVIFDIDKFKAINDIYGHKKGNLILKDIADTLNELTDINETFARVSAD
                     NFNILLTYNKKEDIINIIKKIMANNELVNLSFGIYEIKDKDLSVSVYSDRASLAKSSI
                     KNNSDVNFAFFNDKLREKLLFEDKIEKEMEYALESGQFVMYLQPKYNIKLDKFCGSEA
                     LVRWQYTEKEVIYPGDFIPIFEKNGFIRKIDMYILEQACKEIRSLFDKGISPLPISVN
                     FSRVDFFKKDFIENIVNICDRYKIPYSLIEIEITESSMFGDTDTLFNVSRNLQDIGFI
                     VAMDDFGSGYSSVNMLKNIPLNVIKLDRGFFVDDKDVDKSQIVIKSIVSLIKQLGIRV
                     VAEGIETRSQIEMLKKANCDIVQGYYFSKPLPIKEFEKLVYKI"
     gene            33463..36900
                     /locus_tag="PC465_002052"
     CDS             33463..36900
                     /locus_tag="PC465_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HDF2649347.1"
                     /translation="MIRAKSLKNVLSIVLIFLFTIISFSDFAFKTNVQEEENSKINLR
                     EISLQSSNAIKIKLDSSLSFIKSVANMVSYFNTIDNSKIVPLLANISKESDFQRISIV
                     SPDGISHTSDGKIINVSKYQYFKKAIKGESNISEVVKSPIDGKDTFVIATPVFNKNNK
                     IIGVLYGSYYNDKLAEFIDITSFNSEGYIDIFESSGQFVLKSSHTNKLIKSSSNIYDI
                     FKKASFDDGYSYKKIYEDTKNNKSGFTSYEYKGENRYATYTPIGVNDWYVISVIPQYT
                     VRRNIDKINQLAFSLIFKVFLLFIMLIIYIIYKNNKSQKDILKANKEISSITNSIPGG
                     VQKCTLGETCNINFLSDGFIELFGYTREEIKTLFNNDFYSLIHKDDVERIKKEIFKQL
                     YKNKTVELEYRIITKNGNTVWVLDKGELITEPDGKEYFCCVTVDITRTKQLEQEMEQK
                     NLELEMISENVLGGIIITEFNDDFTIKYANSGYLSMIGYTREQLENELKYKACNLVFY
                     EDRKKALESIQHQLNTKGIAVYQHRIRRRDGNIIWVSIKGRLIVDDDGIEKGIWILND
                     ITDLKNAEQKLKINEERFRIALKQTSNTIFEYDIKTKSLLNTSKELDKYNIYKITKNV
                     PYSLVESGVIHKDFSDDFINMYENVINGAKKASCVVKMKLPDENYIWNKVTLTTIFDE
                     DGNPVRAIGIQEDISKQKEAEIRYNQEGKYHSAILSEAMITYEINVSKDTFIKGNESW
                     QKPFGIKPDNNYSQMVKTIANSIVHKDNKETFLNTFLCENLLDAYKNNVTEIKLEYQR
                     MNQENKMIWVICTMHLIKDSITNDIKALAYVKDIDKQKNEEIRLKLKAERDTLTGLYN
                     KGTTEKLINDFLNSEEASLGMHAFLIVDIDNFKSVNDNLGHVFGDKVLFEVSKNLKPI
                     FRKDDIVGRIGGDEFIVFLKNIQSFENTKKKAEKICDIFRNSYTENKKTYKISGTVGI
                     SFVPEHGTVFEELYKKADIALYYAKSKGKDKYALYNDCIYQNGLENNISDNNIKLADK
                     CEKSKPVLKEILDSIDNYIYIVNPNTYELLFVNNKVSRLDLEIKLGETCYKSLLKSDR
                     PCNNCPLNGLEENKHSKFKIETNTFGKNISIASWINCIDGEYNCLIECIDSSLYKNK"
     gene            36918..37655
                     /locus_tag="PC465_002053"
     CDS             36918..37655
                     /locus_tag="PC465_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HDF2649348.1"
                     /translation="MLNSITLILGIIFTIYYFYLKIVFGGISFSEIFLVVGIVLIIYQ
                     IFKKKIKEKKVFYRVLKIIISIFLIVFVVTESLIIFYPKNSLESKSDYLLILGASVKK
                     TTPSTTLKGRLDTALKYLKINDNCYVVVSGGKGSGEKITEAKAMKDYLIKNGIDKNRI
                     IEEDKSTNTYENFKYSKLKIEEHSQRKLSDLKVKIVTTDFHVLRSKILAYRNGYKNTS
                     FYAKLSFVPTYYTREFFALWKTIIFDR"
     gene            complement(37604..37924)
                     /locus_tag="PC465_002054"
     CDS             complement(37604..37924)
                     /locus_tag="PC465_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HDF2649349.1"
                     /translation="MKKIMNFFKENSTFYFATVEDNKPRVRPFGFIMDYEGKLYFGIV
                     KYKTSYKQLLVNPNVEISTTSKVGKWIRIKGIEKTRYEFISSLFIYYLSKMIVFHNAK
                     NSLV"
     gene            38712..42854
                     /locus_tag="PC465_002055"
                     /pseudo
     CDS             38712..42854
                     /locus_tag="PC465_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897035.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF11 domain-containing protein"
BASE COUNT        17373 a         4655 c         7448 g        13603 t
ORIGIN      
        1 ctttaaaaat taatgttaaa aaataaactt atacattaat attaataata attatttaaa
       61 tatcttaagt aaatcagtct tacatatatt tccgatagat tatattgata aaaaacacta
      121 aaattaaatt aataaaagta cttggaggga tggaaatgaa agaggaaaat tttattaatg
      181 ttgaatacga ggataaacgt ttttcaatta atagtaaaga agttttgtac atagaaaagc
      241 aagagtatga agtaaagatt tatactgaaa gtggtaatta tgaagttgga gaaaatgctc
      301 cttgtataag aaaactattg aaagaagaaa attttttcaa atgcagtaat agttatattg
      361 taaatctaga caagtgtgaa ttttatctca gcaataattg tatttttgtg aataataatt
      421 ttataagaat tttaggttca gaaagaaaaa agaaattaaa aaagaaatta gaaaaattat
      481 atgattatga agattaatat tgggaggctg tattttatac agcctcttta tttattgatt
      541 gtattattaa taaattttaa attatgataa aatataaaac aagtaactta tttcagaata
      601 aaatactttt taaaagaaag ggacgagata tgggagatta taataaaatg attgaattaa
      661 agaataactt aggtatcagt gaaagaaagt taaaatatcc ttgtatctat aaacatttta
      721 aaggaaaata ttatgctaca atgggtctta gcaaggctat tgatgatata gaaaacatat
      781 gtgaaatata tggtaaagaa aatttaatcc aaaacagaaa taaatataaa ttagttatta
      841 gacatactga aagagaagaa gatatctatg tttataggga tttagatgga aacttttatc
      901 ataaaaaaga agaagatact aatgatttag ttttatacaa gaccttatat gatgatacag
      961 gaatatttgc aagacctttg gatatgtttt tagaaaaagt agatacagat aagtatgtca
     1021 attcaattca agaatacaga tttgaagaag tatataaata atatgagaga aatatgctta
     1081 taaatttaga aaaattcttt aacagtacaa taatttgcag aaatacaaat gagatttatt
     1141 gtaaataata tgttagatta gattataaaa tagaaacaaa gtaaagtatt atatgatata
     1201 attaagtttt gagaagtgat aatttatatt taataaaaaa taggcatata ttaggaggac
     1261 atatgggaaa tactttttat atagtaagac atggacaaac ggattggaat atattgggaa
     1321 aaacacaagg tcatggtaat tctgacctta cgcctcaagg tatagaacag gcaaaagaac
     1381 tttctgaaga tattggcaag tattcaattg attatatttt tagtagcgac cttgggagag
     1441 caatgcaaac agctcaaatt ttaggagata agctcaatat tgaagttcaa aaaactgagg
     1501 cacttagaga aatgggattc ggagtttggg aaggcctttt aataaaagaa attcaaaaag
     1561 attattcaga tatatatgca acatggagaa atgaaccaca cttagtaaat ataccagaag
     1621 gcgaaactct taagattata aaggaaagag tagatgcttt tataaaggaa ctaaatgaaa
     1681 aatatgataa taaaaatata attcttgtta cacattcaat tacattgagg gttatgttgt
     1741 tgtcattttt agaatcaggt atggaaaata tatatagaat taagcaagat aatactgctt
     1801 taaatatagt agaatttaaa gattatggac ctgttatagt aaaaatgaat gatacaagtc
     1861 atataaaaaa tcatgtaaag ataaataatt ctgcactgga gtaggaatca attataagga
     1921 gaaatttatg agtaaagtta tagtagttgg tggaggagct tctggaatga tggcagcttt
     1981 gtcagcttca aaaaacaata atgaagtaat attagttgag agaaatggag aattaggaag
     2041 aaaacttagg gcaactggtg gcggtagatg caattttacc aataatagag agatagaaga
     2101 tttttttgat aaagttgtca gtaataaaaa atttctctat agtagtttct atacatttac
     2161 aaataaagac cttatttcgt attttgaaag tagaaatttg gaatataaga ttgaagaaga
     2221 aaatgaccac aaagtataca ctaaaaatga taaatctata gaagtaatag aagtattaaa
     2281 taaagattta ctcaatcaca atgtaaagat aatgtataat aagaaagtta tagatattat
     2341 aactgaagaa attgctctaa aagatgattc taataaggac aagtcaaagt atctaataaa
     2401 agggattatt ttagataatg gagataaaat actaggagac aaggttatta tatcaactgg
     2461 aggagtgagt tattcaaaga cgggttcaga tggttcaatg tataagattc ttaaaaagca
     2521 tggacataca ttaaacaaac tatatcctgc tttagttcca cttacaatag aggaaaaatg
     2581 gattaaagat ttacaaggaa tatccatgaa gaatgtggaa atatcttgta agattaagaa
     2641 aaggaaaata tcaaaatctg gagacatgct atttgcccat tttgggataa cagggccttg
     2701 tgttcttata atgtcttctt atattaacaa gattattgaa aaggaaaagg tagaattaaa
     2761 tatagatttc ttaccaaatt taagtactga tgaaatctct agtataatca gagcatttcc
     2821 aaataaaaat gttctaaata atcttaagca aatactacct caaaatttct taaaagagat
     2881 tttttctcta ttatctttag ttgataaaaa ggcaagtgat ttgtctaagg cagatgaaat
     2941 tagaattatt gagtatataa aaaatatgaa gctaacttgt aatgggacta caggtataaa
     3001 cactggtatg gttacttctg gtggtatttc agttaaagaa attaattctt ctactatgga
     3061 atctaaatta gttaagaact tattttttac aggtgaagta attgatatag atgcagaaac
     3121 tggtggatat aatttacaaa tagcattttc aactggatat cttgcgggta taagtgtata
     3181 aatataattt tttaataatt aaatatgaat aaatagaggt gtatatatgg gtaatttagt
     3241 tatagctgta gatggtccag caggagctgg aaaaagtaca atagccaaga tagtagcaaa
     3301 aaagctaaat ataaattata tagatacagg tgctatgtac agagcagtta cttataagtg
     3361 tttaaaaagt ggtattgatg tcaataatgc aaaagaagtt attcaaatag ctgaaaattc
     3421 ggatatagat tttaaagata acaatatata tttggacaac gaagttataa atgaagaaat
     3481 aagaacaata gaagtaagca ataatgtttc taatgtagca aaaataaaag aagtaagaca
     3541 gttgatggtt gaagttcaac gaaaaatagg aatgaaaagt tcagtaatac tagatggtag
     3601 agatataggt tcatatgttt tcccagatgc agattacaaa ttctttttag tagctactcc
     3661 agaagaaaga ggaaatagac gctataaaga actttgtaat aaaggatata atactacttt
     3721 agaagaagta attgaggata taataagacg agatgaaatt gattcaaata gagaatttgc
     3781 accattggta aaagctaatg atgcactaga aatagatact acaggaaaaa ctatagaaga
     3841 agttgtagaa gaagttgtat ctaaaataaa tctttagttt tttatgcatc ataatgaaaa
     3901 taaatgtagt gttgaaggga gataaacgtg aatttttata gatttgtaat aaatattttt
     3961 aagggttttt ctaaaatatt ttttaaatat gaagttatag gtgcagaaaa tattccagat
     4021 agaggaaata tagtaatagc atcaaatcat aaatcgaatc ttgaccctat attcttggct
     4081 gctgccatag aaaatagaga aatagctgca attgcaaaga aagaattgtt taaagtaaaa
     4141 cccttgggat ttatattaaa aaaattgcat gttatgccta taaatagaga aaaaccagat
     4201 gtatctacaa taaaaactat tttaaggtca gttagagatg gttatgtatt aggaatattt
     4261 ccagagggta ctagaataaa aggagattct tttggtaagg ctaaggcagg tctttctgta
     4321 tttacaataa aaagtaaatc taaagttgtt ccagtatcaa taatatctaa atataaactt
     4381 tttagtaaag taattgtata tattggagaa ccaatatcat ttgaagaaca ttttaaggaa
     4441 aaattgagta atgatgacca tgaaaggata tcacaagaga ttttagaagt gataaaacaa
     4501 aattacttta aatattcaaa ataagggggt aaagttatga acataaaaat agcaaaaaat
     4561 gctggctttt gttttggagt aaaaagagca atgaaaatgg catgggatga agttgaaaaa
     4621 aatgattctg gcatatatgc tttaggtcct cttattcata acaagcaagc agtagcaaaa
     4681 tatgaagaaa aaggtcttaa gactgtgaat gaaattgata caataccaaa tcatgaaaat
     4741 atgataataa ggtctcatgg agttcctgaa aatatatata aggaagccaa agataaaaaa
     4801 ttaaaaattg tggatactac atgtccattt gtaaagaaaa tacatacagt agtaagtgaa
     4861 tatcataata aaggctatga aataatagtt attggagata tgaagcatcc agaagttata
     4921 ggtataaatg gatggtgtga aaattcagct ataataataa agaccttaga acaaatggaa
     4981 aatatggaat ttgataactc caaaagatat tgtcttgttg cacagactac aataaatcca
     5041 gagttgtata taagtatagt taataaacta tcagataaat tagaagaaat agtatttaat
     5101 gatacaattt gttcagctac aaaaacaaga caagaatcag ctaaagagtt agctaaagaa
     5161 gttgattgta tgatagttat aggaggtaaa cacagttcaa atactcaaaa gttagtaaag
     5221 gtttgtgaag acttagtacc aacttttgca atagagacta aagatgaatt ggatgtaaat
     5281 acgcttaaaa aatataaaaa tttgggtatt acagcagggg catctacacc taattggata
     5341 atagaagaag ttgtaacatt ccttgaaaat ttataatttg ataggtaata aaaataggtg
     5401 gacattgtta taatttatca taatatccac ctttgatttc atattacatg tggtaaatag
     5461 ataacctaat atcaaaaagt gtgtatctta agatgaaaaa ctaatagtat aagatgcgca
     5521 ctttttaata ttagaaattc aaaagaaatg ttgatattga ttatcaatag aaaataaaat
     5581 ataatataat tgttgcaaaa ttagtctagg aggtaaatta atggaaatgt tgatatccgc
     5641 ttctgaagag gcgtttttac atgtaggttc tatgattgga ttttttattt tgttatttgg
     5701 atatattaat tataaaacta gtggaaattt tactaatatc atatcaaaaa acagaaaatt
     5761 tcaaccatta ataggtgctt taattggagc tataccaggt tgtggcggaa gcttggcaat
     5821 aatgccattg tatataaatg gaaaattaag ctttggagca ataattgcaa gtttaatagc
     5881 tagtatggga gatgcagcat ttgtacttat ttcatcaaat attaaaatgt atttttttgt
     5941 cactatagtt agtacaatta caggaataat aactggacaa ttagtggatt actttaaact
     6001 agaagaaaaa ttagggttaa aaaaccgtag aaaatcagat aaatacgata taagtaaaaa
     6061 taactctaaa gaaaataaag aacaacataa tcatgatgaa ataattttag acactctagc
     6121 taaatctcat ggaaatacaa atagacttgc atttataata acacatggaa agggatataa
     6181 aatttatata ggaattatag taatcggttt tatatttatg tcacttgctc actctggact
     6241 taatcttcct ataattgaga agttacattc attggaagag gtaatagcag tgattggaat
     6301 attattttca ataatttata tgtggtgttt taaaaaggta tttaaaaatt ctaatcaaaa
     6361 agaggaagaa aataaaaaga tttctttgcg agaaatgctt atccattctg ttggagaaat
     6421 atcatttgta attacatgga tttttattgc atatcttatt tacgatttga taatattaat
     6481 tttaggtgga gatgaatact tagttaaatt agtattatca acaggtgtaa taagtgtatt
     6541 tataggtgca ggtcttggac ttattccagg ttgtgggata caaattgtgc ttatgtcatt
     6601 ttatttgaag ggaactatac cacttggtgc agtgatagcc aactctattt ctcaagatgg
     6661 agatgcactt ttcccacttt tagcaatgga taaaaaatct tctttatggg ctatgattat
     6721 tactactata ccagcaatac ttgtaggtat gatagtttat gcatttttag gttaaatata
     6781 attatgaata aagaagtatt aaaaaaataa taaagcacat aaatttattt ataagaatag
     6841 tgaagattaa atataaaaat aaaaaattca atatgaatta aattattgct taaatattaa
     6901 tgagaacatg ggagataata ttattcctca tgttctctct atttaattaa aggaattatg
     6961 gaacaaattt caagtgatac tttctatcaa aactcatata taatatatat taataaatta
     7021 aactataata cgtaatacag ccagtatatt gatataaaaa acttaggagg agttgtaaaa
     7081 atgggtaatt taaaaagaca gtgtgatgtt tcaagtggaa gagaaaaagc tgacattgta
     7141 ctaaaaaatg ggacaatcat aaatgtattt acagaagagt taataacagg agatgtagca
     7201 atagtaggag acactatcgt tggcattggc gattacaagg gcaatgtaga aattgattgt
     7261 agtaacaaat atatatcacc tggctttatt gatgcacata tgcatattga atctacaatg
     7321 gtaatgccaa ttgaattatc gaaaaaatta ttaaaatcag gtacgacaac tatcatagcc
     7381 gacccacatg agttggtcaa tgtaaaagga gctagtgcaa tagatttttt attagaatcg
     7441 acaaaagata taccacttaa tgtatatatt atggtgcctt catccgtacc tgcaacaagt
     7501 tttgaaacta atggagttgg taaatttagt gcaaaagaca tggagagtta tgtaaataat
     7561 cctagaattt taggtttagg agaggtaatg tgttttaatg atgttataaa ttctgaaaat
     7621 gaaatcttgg ataaactaga gctttttaaa aataaagttg tagatggaca tgcacctaat
     7681 ataaatggta aatcacttca gacatatgta tgtgcaggaa tagaaaatga ccatgaatgt
     7741 ataacttttg atgaagtata tgaaaaattg agagcaggat taaaaatttt aataagagaa
     7801 ggaagcgcag caaaaaattt aaagtctata gtaagtggta tgctaaagca taacttgcca
     7861 attgaagaat ttatgttttg cacagatgat aagcacttag atgatataga aaaacaaggt
     7921 cacataagat ggaatataaa atgtgcgatt gatttaggta tggaacctgt tagggctata
     7981 aaagttgcaa cttataattc tgcaaaagca tatgggttaa ggaaaattgg agcaataggt
     8041 gcgggttata aggcagatat tgttgtattg aatgatttag acaaaatgga agtggatagt
     8101 gtatataaag atggtaattt ggtaaacgaa gagatgtttt ctaattacaa ttatgagatt
     8161 aaagataaag aattgcttaa tacagtcaag tttaaatata ttaataaaga aaaaatacag
     8221 ttaaaagtaa gtgaaaaaaa ttatgtaatg gagattgtac cttatcaaat tttgacaaat
     8281 aaggtatatg aatctttacc atgtgcagat ggatattttg ttccaaataa agagtattca
     8341 aaactttgtg ttgttgagag acatagaatg actggaaatg tagcaattgc tccattaaaa
     8401 ggatttggca taaaaaatgg agcaattgct actactgtgg cccatgattc tcataatatt
     8461 atagttgcag gggataatga tgatgatatt ctagtagcta taaattactt aaaggaaata
     8521 caaggtggtt atgtaattgt atcaaatgga aaagttcttg cacacctaag tcttcaagta
     8581 gctggattaa ttagtacttt tacagctgaa gaagtacaag aaattactga taatatgttg
     8641 gagatagcaa gaaaaatggg agttccagag tatgtagacc cttttattac actttctttt
     8701 atggcacttc cagttgttcc acaaataaga cttacagatt taggtctatt tgatgttgag
     8761 gaatttaaat ttatatagat aatataaaag taataataaa tgaggctttc tcaaaatagg
     8821 gataagtctc tttttattgt tgaaatgatg aaaatatatt tgatttcata caaaaaagag
     8881 catctcatga actaaaaatt ttatttttag atatccttat tttaattaat ctatcattta
     8941 accttgtttt aagcatagat atcttaataa aactattttc agtctatttt aacatataaa
     9001 tacatgaaaa ttatatattt atgaaacttt atacataaaa aataaaatat tttatttata
     9061 tatagattta tagggtaata atataagcat agtataaaat tattaataaa aacaaaagga
     9121 gagatattta tgttgagtat aggaacaaaa gcaccagaat ttacactaga agataaagat
     9181 ggaaataagg taagtatgtc agattttaaa ggtaaaaaag tagtagtata tttttatcct
     9241 aaagataata caccaggatg tacacgtcaa gcttgtgctt ttagaaatgc atatgatgga
     9301 tttaaaaagg aagatataca agttattggg ataagtaaag atagtataaa atcacatcaa
     9361 aaatttgcag aaaagcatga acttcctttt attttacttt ctgaccctga cttagttgct
     9421 ataaaagctt ttgatgtatg gaaagagaaa aaaatgtatg gaaaaactgc attgggagtt
     9481 gtacgtgcga catatattat agatgaaaat ggaattattg aaaaagtctt tgaaaaagca
     9541 aaaccagaca caaatgcaca agagattctt gaatatttgg aaaaacagga gtaataagaa
     9601 tttatgatta taatgttatc accagctaaa aatatgaaga atatagaagt atttgataga
     9661 gatttgagtt tgccttgctt tatagataac acaaaagaaa tagtggaaaa tataaagaca
     9721 tttggtatag aagattttaa aaataaaatg aaaattaatg aaaaattagc tgtattaaat
     9781 aaaaatagat ttgaaagcat taaatttgat agattaggaa accctgcaat cttaacttat
     9841 gatggaatac aatataaaaa tatagaagca gaaaatttta caaggaaaga tgaagagttt
     9901 gcaaatagct gtattcgaat cataagtgga ttgtatggtg ttgtaaaacc atatgatagt
     9961 atatatgaat atagattaga aatgcagaca aaattacaag taggtgagtt taagaattta
    10021 tacgaatatt ggggaaatcg tatatataaa gaactaatca aagaaaaaac agctatcgtt
    10081 aatctttcat caaatgaata cagcaaatcc atagaaaaat ttattaaaga tagtgataca
    10141 tatattacat gtacttttaa agtaaataaa aatggcatat tgaaagtgga atctacacaa
    10201 gcaaagaaag ctagaggtat gatgacaaaa tacattgtaa aaaataggat aagagatatt
    10261 gaagaactga aaaagtttga tttagaaggt tataagtata aagaaaactt atctaacaat
    10321 agtgaataca tatttgtaaa agagtagaag ttttgttaaa tattaaatgg cattgttaaa
    10381 tttaggtaaa atatacttag tgtgtattga attgaacttg attttaaaat ataattattc
    10441 ttaaattaaa aaaagaaagg agtggtcttc caaaatggaa aatcacaaac agatgccttg
    10501 gcattcaaga gcaacgcatg aaattttaga aagtctagat tcatcagagg aggggctcac
    10561 cgataccgag gcggaaaaac ggcttaaaga gaatggctta aatgaactta gaaaaaaacc
    10621 acctagaaca actttacaaa tgctttggag tcaaattaca gatgctatgg ttatgatact
    10681 aataggagca gcaatattat ctttgatatt tggcgaattt acagaagctt ttgtaatact
    10741 aataattgta acagtaaatg cagttattgg aattgttcaa gagaaaaaag cagaatcatc
    10801 attagaagca ttaaaaaata tgaattcacc tacagctcgt gttatgcgtg atggtgaaga
    10861 aaatgttatt ccagcaagta atcttgtagt aggagatatt gtttttttag aagatggagc
    10921 tatggttcca gcagaccttc gtttaataga aacatcaagt ttaaaaattc aagaggcttc
    10981 tttaacagga gaatctgttc catcagaaaa agatgcagat acaatcttac ctaaagaatg
    11041 tgtattagga gaccgtagca atatggcgta tacatcttca atagtcacat atggtagagg
    11101 tgtaggtgtt gtagtagcaa ctggtatgga tacagaagtg ggtaacatag cacatctttt
    11161 agattcacaa gatgattttg atactcctat aaaacgtaaa cttaatactg ttggaaagac
    11221 attaagtgtc ataggtatta ttgtatgcgt tgttatattt gcaataggtg cattttatca
    11281 gagacctctc ttgccaatgt ttatgattgc aatttccctt gccatatcaa ttattccaga
    11341 gggattacct gcaacagcta ctattgtaat ggctttaggc gtacagcgta tggctaaaag
    11401 aaatgcttta attagaaaat tacctgctgt tgaaacatta ggaggagcta cagtaatatg
    11461 ttgtgataaa actggtacat taaccttaaa taaaatgact gttacacata ttgctgtcaa
    11521 tggagatttt gaatctggaa aagtgacatc aatagatact gcatctgaaa aacatccatt
    11581 agtgtataaa gagattgttt atgctggtgc actttgtaat gatgcatgta ttaatccaga
    11641 taaaacagat gaaatattag gtgacccaac agagggcgca ttaattttta tggccaaaaa
    11701 atttggaata gatcaagaag ctcttgaaga agaatatcca cgtgtatttg aacagccttt
    11761 tgattcagat agaaaatgta tgacaactgt tcataatata gatgaaaaga ttattgctta
    11821 tactaaagga gcagtagacg aaattcttga cctatgtact aaaatattaa cttcaaaagg
    11881 tgaaagaaac attaccgaag tggataaaaa gaatatacac gaattatgtc ttaacatgtc
    11941 taaagatgca ttgcgtgtac ttggttttgc taagcgtgag atttcatcta taccaaaaga
    12001 agatagtgaa aatatagaat atgatttaac atttataggt atggttggta tgattgaccc
    12061 accaagaact gaggtaattg atgcagtaag tacttgtaaa gaagcaggta taagaaccat
    12121 aatgataaca ggtgaccata aagttactgc cacaacaatc gctcatgagt taggaatatg
    12181 gagtgaagaa aatactgtga tatctggtga tgaacttgat aatttgagtg atgatgaact
    12241 agatgaagct gttaaaaata ctacagtatt tgctcgtgta tccccatttg ataaacttag
    12301 aattatacaa tctctaaaaa gaattggaga agtaccagca atgactgggg atggtgtaaa
    12361 tgactctcct gccttaaagt ctgctgatat tggtatagcc atgggtataa gtggtacaga
    12421 tgttgcaaaa gattcttctg acatgatttt aatggacgat agttttacaa caattgctta
    12481 tgcaataaaa gaaggtagac gtgtatatag aaacatacaa aaagttatac aatttttgct
    12541 tgttggtaat atagcagaga tacttacgtt gtttgtagca atattattaa attgggatac
    12601 tccgcttctt gctgttcata ttctatgggt aaaccttgca actgctacgc ttccagccct
    12661 tgctcttgga gttgacccac caagcagaaa tataatgaag caccagccag tgaaatcaac
    12721 cactttgttt gaaaaaaatc ttatacaaag agttgttacc caaggtatat ttgtggcaat
    12781 aatgactatt ttagcatata aaattggtct taatatagaa aatcattctg taggtcaaac
    12841 aatggcattt tgtgtattag cattttcaca gatgttacga gcatttagtc agcgttcaaa
    12901 tacagattca atgtttaata gaaataatgg taaaaatcca tttcttttaa tctcattttt
    12961 aacttctgca tttttaatag cagtaatact atttgtacct gtttttagaa atgcttttaa
    13021 cttaacagtt ttaaataact tagagtggct tataacgatt gttttagcca taatgtctgt
    13081 aattcaagta gaggttggga aaattattaa aagaaaaaaa ttaaaaaaat agttgacaaa
    13141 attaggaaaa atatataaga tataaaacat agaaaaatta aataaatctt atccagagag
    13201 gtggagggac tggccctatg aaacccggca accagtatat ttatatacat tggtgctaaa
    13261 tcctgcggcg aaagctgaga gatgagtata attaagctta tacagagcct gagttatata
    13321 ctcaggcttt atttatttta actctcatct ggtaaatagt ttaatttttt ttactaaaat
    13381 ctaaggggga tacaagaatg tataataaag aaacaatatg tgtgcaagga aattataaac
    13441 caggtaatgg agaaccaaga gtactacctt tatatcaaag tacaactttt aaatatagca
    13501 gtatagacca acttgctgaa ttatttgatt taaaagttga tggacatata tattcaagaa
    13561 taagcaatcc tactattcaa gcttttgaag aaaaaataag tttactagag ggtggagtat
    13621 cttctgtagc tgtatcatca gggcaatctg caaatatgtt ggcagtttta aatatatgta
    13681 aatcaggaga tagtatactt tgttcttcaa aagtatatgg aggaacattc aatttactag
    13741 gacctagtct taaaaaattt ggtatagatt taatatcgtt tgacttagat tcaagtgaag
    13801 atgagatagt agaacttgca aaggaaaata ctaaggttgt gtttgcagaa acacttgcaa
    13861 atccaactct tgaagtcata gattttgaaa aaatagcaaa tgtagctaag agaattaatg
    13921 ttccatttat tgttgataat tcattagcat ctccagtgct ttgtaaccct ttaaagtatg
    13981 gagcaaatat agttactcat tctaccacaa aatatttaga tgggcatgct tcaagtgttg
    14041 gaggaattat agtggatggt ggaaacttta actgggataa tggaaaattt ccagaattag
    14101 ttgagccaga cccaacatat catggtataa gctatactca aaaatttgga aatgccgcat
    14161 atgcaactaa agcaagagtt cagttgctta gagactatgg aaattgttta agcccattca
    14221 atgcatatct tactaattta aatgttgaaa cactacatct tagaatggag agacatagtg
    14281 aaaatgcact taaaatagct agatttttag aaaaacatga aaatgtagat tggattaatt
    14341 acccaggact tgaagataac aagtattatg agaatgccaa aaagtattta tcaagaggat
    14401 gtagtggtgt tttatcattt ggagtaagag gtgggttaga aaatgccaaa aaatttgtgg
    14461 aaaaattaca gatagcatct ttggttacac atgtttcaga tgtaagaact tgtgttatac
    14521 atccagcttc aactactcat agacaattaa cagaagaaca attaattgca tctggagtat
    14581 tgccttcact aataagatta tctgttggaa tagaaaatgt agaggattta atagctgatt
    14641 taaatcaagc tttaaatttc taatattcta agagaaagag aagtgaaaag atatggcttt
    14701 aatactacca aagggattac ctgttattaa taaattatta gatgaaggaa tagatgtaat
    14761 ttataaagaa gattttaaaa aggaattaaa atatgaagaa aacatagaca ctaagatagc
    14821 tatactaaat ctaatgccta taaagataga tacagaatta gatttactaa gaaggataga
    14881 taaaacagga ttcaacgtgt ctgtggaatt tattaaaatt tcaacaagag aaagtaaaag
    14941 aagttgtaat gaatatgtta aagaatttta taaaacattt gatgaagcca aaggagagta
    15001 ttttgatggc tttataataa caggagctcc agttgaacaa atggagtttg aagaagttga
    15061 ttattggaat gaactagaag aaattatgga ttattctaag agaaaaacta aatctacatt
    15121 atatatatgt tgggcagctc aagcaagtct ttacaaatac tacaatgtaa aaaaacttcc
    15181 actaagtcaa aaatgttttg gagtatttaa gcataaggta gataaagata gtaaaatagt
    15241 agatggattt gaaaatgaat tttttgctcc acattcaaga catactactg taaatattga
    15301 agctttgaaa gagaataaag agttgagcat tgtgagtcat tctaaagaag ctggtcccta
    15361 tataattaca aattcaagag atgtgttcgt aatgggtcat agcgagtatg acaaatacac
    15421 tcttgataaa gaatataaga gggatataaa taaaggagat aaaatatcta tacctcaaaa
    15481 ttactatatt aatgatgacc cttcagaaga gccaactgta aaatggaaaa aacattcaga
    15541 attgttgttt agaaattgga taaaaaacta tttgatacaa taaattttaa gagtatataa
    15601 atgttaacta aaaaaatata gaaatttata ggtataaagt taatcttaat gatactttat
    15661 accttatttt tttaaaattt gaccttataa tagtagtttt atattttaag aaaatcactt
    15721 taggtgtatg tagatagagg tggctttaat tttatatatg gtgcgataat gggagactaa
    15781 acctttatag tatcaataaa tttgtatttt aacttttaaa agagattaaa aagggagaaa
    15841 tcagtgtaaa atatatatat agatttttta ttaaatttta ttaaaaatat cctgtataaa
    15901 attaaatatc aataagataa caaaatttca attgaagtta caatattgta attgacaata
    15961 aatacttaat actataatat ttaatacatt aaacattata gtgttaagta tttatttaca
    16021 gtatgcactt cagcctaaat ttgaaataaa gtattttcgt agggagcgtt tgtatggatg
    16081 agatgagttt taagaaagag ctactagagt tgactagaga tataaatatg aaatttacaa
    16141 ctttattaag tgatttttat cagccacttg gtattacagc agtgcaagct ttgattttat
    16201 ctgagttatg tgaacatgga gaaaaaaaaa taagcgattt agggaagaac ttaaacatga
    16261 caaatagtaa tgtatcagta atctgtcaaa ggcttgaaaa aaatggcttt ttaaatcgca
    16321 taagagatat agaagaccaa cgaattgtaa aagtaaaagt tacaaataaa tcattggata
    16381 tacaagaaca tatttcaagt agtatttttg atagttattt tgaaaatatg accagtgaaa
    16441 aattgcaaga tatggaagat ataatagaag gtttagagaa attaaataaa cttttaactt
    16501 acattgattg caaataacat aaaaataatt taaaggagaa taaaattatg gatgaacata
    16561 aaccccaaaa aaggtcagca ctctattatt atacagttat aataatagta gtaatgtttt
    16621 taaatgcttt aatatttcca agtttaatgg ataaaaaaat ggttgagatt gactatggaa
    16681 agtttctcac aatgttggat acaggaaagg ttaaatctgt tgagatagaa aataatagaa
    16741 tagcaataaa tccatctagt agcaaggata agaatatata cataactggt agaatggatg
    16801 acccagaatt ggtagataga ctaaaaaatg caaaagtaga atttactaag gttattccta
    16861 aggaaaattc acctctttta agtattttac ttacatggat aatacctata ggtattctta
    16921 tgctatttgg taacttaatg atgaagtcta tgcaaaagcg aatgggtggt aatgctatgc
    16981 aatttggaaa aagcaacgcc aaaatgtatg tatctgctca aagtggaaaa agatttaatg
    17041 atgtagctgg tcaagatgag gcaaaagaag ctttaactga aatagtagat ttcttacaca
    17101 atccagaaaa gtataaaaag ataggagcac aaatgcctaa aggagcactt ttagtaggac
    17161 ctccaggtac aggaaaaaca ctccttgcaa aagctgtagc aggtgaagca aatgtaccat
    17221 ttttctcaat atctggttct gagtttgttg agatgtttgt aggaatggga gcttctagga
    17281 ttcgtgattt atttaaacaa gcaaaagaaa aagctccatg tatagtgttt atagatgaga
    17341 ttgatactat tggtaaaaag cgtgataatg gaagtggatt aggtggaaat gatgaacgtg
    17401 aacaaacttt aaatcagttg ttaagtgaga tggatggttt tgatggtgga attggagtag
    17461 taatacttgc tgctacaaat agacctgaca gtcttgacaa agcattactt cgtccaggaa
    17521 gatttgatag acgtatacca gttgaacttc cagaccttgg aggacgtgaa gctatattaa
    17581 aggtacatgc tcaaaatgta aatgtaagct cagatataga ttataatgca attgcaaggt
    17641 ctacatcagg agcatcaggt gcagaacttg caaatattgt aaacgaagca gcacttttag
    17701 cagttaagtc tggcagagat atagtagaac aacaggattt tgatgaatct gttgaaactg
    17761 taattgctgg gtatcaacgt aaaggagctg taatttcaga taaggaaaag aaaattatag
    17821 catatcatga aataggtcat gcacttgttg ctgctatgca aaaacattct gcacctgtcc
    17881 ataagattac tataatacct agaacttcag gagcattggg atatactatg caagttgctg
    17941 aagatgagag tgtacttatg tctaaagaag aagcaattga taaaataact acttttacag
    18001 gtggtcgtgc tgctgaagag gttatcttta acacttgtac atcaggagca tcaaatgata
    18061 tagaacaagc tactaaaatt gcaagagcta tggttactcg ccttggtatg agtgaagagt
    18121 ttgatatggt cgctcttgaa actgtaagca atcaatattt aggaggagat acttctcttg
    18181 cttgttcttc cgacactgct gctaaaatag atgaagaggt atttaaaata gtaaaggctt
    18241 gtcacaaaaa tgcaattgaa atcttagaaa ataatattga taaattgcat gaacttgcta
    18301 attatttatt agaaaaagaa actattacag gtgatgagtt tatggaaata cttaacttaa
    18361 actaaaatga ttatacacaa gataaaaatg cctattgtta ggcattttta ttttacaact
    18421 aaatttttta aattcatatt taaatcttta cataatctta atcattaaaa atacatctta
    18481 actacaattt tatatcggaa ttgatattat aatagtaatg aatggtgtaa ggaggttttt
    18541 taatggatag acctaatcct gatattctat tagaaaaaat taaaaatgaa gaagaaaaac
    18601 taagtagagg tcaattaaaa atattctttg gttatgcagc tggagtagga aaaacctact
    18661 ctatgttgga atctgcacaa aatttaaaaa aagtgggtgt agatgtagta gttggatata
    18721 ttgaaccaca cactagacca gaaacattgg ctttacttga tggcttggaa attcttcctg
    18781 taaaggagat agaatataaa tctataaaac taaaagaatt tgatttagat gctgctttag
    18841 caagaaaacc agaagttata ttagtagatg aatttgccca ttctaatgtt gctgggttaa
    18901 ggcatacaaa aagatggcaa gatatagaag aattgctgtt agcaggcata aatgtctaca
    18961 ctactgtaaa tgtacaacat ttagaaagtc taaatgacat tgttgagata attacaaacg
    19021 tatcagttaa agagactata ccagataagt ttttggatac aaatacacag ttagaactta
    19081 tagatgttga acctgatgta cttcttgaaa ggttcaatga aggtaagata tataagaaag
    19141 aacaagctac tagagcaaaa aataattttt ttataaaaga taacctggtt gcacttagag
    19201 aaatcgcact tagaaaaact gcagagagag ttaataaaga agttcaaatg accagactat
    19261 caaagggtga tgtaactgta atacctacat cagatacact tcttgcatgt ataagtccat
    19321 ctccatcttc agcaaaagtt attagaactg catccagaat atcagacagt acatttgcaa
    19381 aatggatagc tttatatgtt gaaactccaa acacagcaag acttccattt gatgaacaaa
    19441 aacaactaca aaataaccta aaattagcta agaaattagg tggagaaata attgttttac
    19501 atggtgaaaa tataatagag caaatactta gaattgcaaa gctgagaaat gtaacaaaaa
    19561 ttgtaatagg tagaaatcat tcaagtaata aaagatttag taaaagattt aaaaaagata
    19621 tagttgacaa attaattgat gaagttgatt atatagatat acatataatt ccatataaat
    19681 ttgcctcaga tgttaaatac aaacctaaaa aggataaatc atcaataaaa tctaaattta
    19741 aaattagcaa agttgatttt ataaaactta tatttattac tttgatgata agtattttag
    19801 catatgcagt acaaagcatg ggatttataa gagaaaatat attgttaata tatatgttgg
    19861 gtgtagtttt agtttctatg tggactaaag ggtatagtac aggtataata agttctgtat
    19921 ttaatatagt tcttttaaat tattttttta cagcaccatt atatacatta tctatagcag
    19981 attcaaacta tatagtaaca ctggttgtat tctcaatagt aggtataata actagcactc
    20041 ttacgtctaa gatacagcat gaagcagaaa ctgctgctaa aagagaagaa aatacaaaaa
    20101 tgatatatca aataattaag ggatttttaa gattatcaaa taaagatgat atagtaaaca
    20161 aaggtataga acttttgtct cttagcttaa gtagagatgt aatttgttat ttaaatgtag
    20221 ataagcataa taaatcaaag ctttacaaaa aaaatactaa taataaggat aaaaatgatt
    20281 tggatagtga agatgaaaaa gctgttgcaa gttgggtttt atccaattca acagtggcag
    20341 gaaatgacac ggatacactt cctggttcaa agggatacta tataccaatt gtaggaatga
    20401 atttaacttt aggagtagtg ggaatatcat gtattgattc aaaattggat acagaagata
    20461 taagcttaat tgaaacaata attgctcaaa tggcaatagc gcttgataga gaaatcttgt
    20521 cagaagctaa agaaaatacc aatcttgaga ttgaaaggga aagattaaga agtaatcttt
    20581 taagagcagt ttcgcatgac cttagaactc cactagcagg aatatctggt gcagtaagta
    20641 caattataaa aaacaagggc actataggtc aagatataat agatgaatta cttagtggtg
    20701 tatatgaaga tactcagtgg ttaataagac ttgttgaaaa tttacttagt atgaccaaga
    20761 tagatgaagg gaaattggaa gttaaaaaac attctgaact ggttgaggaa attatatcag
    20821 aagcgttaca aaaaataaaa aaaagaattg aaaatgcact tatagatatt aatataccag
    20881 aacagatatt atttgttcct atggatgcaa aattaataga acaagtttta attaatttaa
    20941 tagataattc tttgaaatat tcaaaggaag attgtaagat agagataaat gtatatgaga
    21001 aagatgatta tgtttggttt gaagtatctg ataatggtcc tggtatatca aaggaactta
    21061 aaaagcatat ctttgacaga ttttttactg gagaagaagg agctaaagat tccagaaagg
    21121 gtgttggact tggattatca atttgtaaat ctataattca agctcataaa ggtgaaatta
    21181 tggtagaaaa caataaagat aagggttcaa cttttaagtt tagtttgcct aaggaaaatg
    21241 aatagtttta aattttaaaa ttagttttgg aggaagaaat gagtaaaaaa cttatattgt
    21301 tagtagagga tgataagaca ataagaaaat ttatatctac tgcactttta acacaggatt
    21361 atgatgtcaa ggaggctata actggaaaag aaggtatatc tatagctgtc tcatattctc
    21421 cagatgttgt tcttttagat ttaggcttag aagatatgga tggaatagag gtaataaaag
    21481 ctatcagaca attttcaaat ataccaataa ttgtagtttc agctagagag caagatagag
    21541 acaaggtaga agtatttgat gcaggggcag atgattactt aacaaaacca ttttccatag
    21601 tagagttatt agcaagagta agagtagcat ttagacattc acaagtagaa gctcaacaaa
    21661 aagatgatgt taaatctacg tttgaagtag ataaattatt gattgatttt gataaaagaa
    21721 aagttattgt tgatgatgtt gaagtccatt tgacacctat tgaatataat attctttcat
    21781 tacttgcaaa gcatcatgga aaagtgctta ctcataattt tataataaaa gaaatatggg
    21841 gtagtgttat agggaatgag actaagtctt taagggtttt tatggcaacg ttaagacgaa
    21901 aaatagaaaa acaacctgca aacccaagat atataattac agaagttggt gtaggataca
    21961 gattaaatga tgaatagttg taatatatta attattagat tatgtgctta ttaatatata
    22021 ttaaaattat atagtttagt taaaataaga atgaagtgta tgtgcttgtt gtcagtttag
    22081 cacatgcatt ttatttttta gcttttttag tatcaataat tttttagtat caataatatg
    22141 aaatatgttt taaaataagt atatagtgta atctgtaata aaaactttgg ttaaataata
    22201 aatgtattta acacttacct tataataaat ttaatataaa tattaaataa taattattaa
    22261 aatagtgtaa aataattaca gtaaggatta taaaaaattt ttagaatgta aattgaaatt
    22321 taggagtaga tgtatgtata tactgaattt aaatacaaga gagactattg aagattttag
    22381 agataaattt tatgtagcag aaaattctta tcttatatta agtgctccaa aaaatttaaa
    22441 attgcttaag gaaactttgg atatagatga aataactttt aatgattgtc ttaaatttga
    22501 tgaaataacc aaacttgatt tatttgataa ttacgatttt ttaagcctaa atacatttga
    22561 actaagagat ggagaagctg ttatagaaga ggtaaatatg tatttatcag ataattttat
    22621 attggttgta gtgaatgaag aacacttttt atttgaattt gtaaaaaata ttattttgaa
    22681 gaactctcaa cttgaaaaaa atccagttat taatctattt aagataaact acttgattct
    22741 tagagaagtt ataaaaaatg gttttgagtc tttggaaaaa gttgaagagt taattcttca
    22801 aatagaagat gaaatgatgg acaacattaa taagaatcat gtatctagaa taagtgatgt
    22861 aagaggatta acaagaatta tagttaagaa tactagacct cttttgtata ttggggatag
    22921 aatagttaag gaaaatataa gatatttaaa atattcaaat gtaaaaaaat ataatttaga
    22981 aaattttcaa ggtatagatt ttggaattga caaattatac aatttcgcat tgtcaacacg
    23041 agagttagca gataaattat tagatattta ttcttccaga gtaggtgaga aaacaaataa
    23101 cttaattaca aaattaacct tgttaacagc catatcagca ccacttacaa ttataactgg
    23161 tatatatgga atgaacttta gatatatgcc agaattaaac tggatttatg gatatccagc
    23221 aactttattt tttatgctat gtataatttt tgttggaatt ataatattta aaataaaaaa
    23281 attattgtaa attacagatg atgtttaatt gattttataa aaatacatca attgagaagc
    23341 tgatttaagt aaataaaaaa atattttaaa ttgaaaatat ttatagaaaa tattgacaat
    23401 tatattttct ttgttataat tattaaacaa gaagaataat aaattataaa aatggaggat
    23461 aatactatga aaggaatatt aaaagaacta acagcaaaac tttatagctt tttttacttt
    23521 atgttctggg gcttttattt tagcgctggc tatttctttt acaaaaatat atgtacttcc
    23581 tttctggtga ggccttattt tagtgatttt gagcataagt aaattttata aaaatgatta
    23641 ttttatatat ttatataaga tttagtgctt gatagattat tttagagaac tcattagtga
    23701 gttctctttt ttattttaaa tataaaatta taatattggg aggtagtaaa aatgatagta
    23761 gtattaaaaa tgggagcaga taaaaatgaa gttaaaaaat taattgaggc tattgggaga
    23821 gaaggagtag aagttaatcc catagatgga acagaattaa ctgttttagg tttagttgga
    23881 gatactagta aaatagatgc caaaagaata gaagcaaata aggtagttga aaaagttatg
    23941 catgtggtag agccttttaa aaaggccaat agaaaatttc atccagaacc ttcaatcata
    24001 aatgttaatg gaatggaaat tggttcaaag aaaattgcta tgatagctgg gccttgttct
    24061 gttgaaacag aagaccaaat agtatctata gctaaagatg tgaaaaaatc aggtgcagga
    24121 tttttgagag gtggagcatt caaaccaaga acatcaccat acgctttcca aggattgaaa
    24181 tatgatggat tggatttatt aaaaaaagca aaagaaaaaa cagggcttcc tatagttaca
    24241 gaaataatgt caacacaaga tatagatata tttgaagaaa atgtagatgt aattcaagtt
    24301 ggagctagaa acatgcaaaa ctttgattta ttaaaagaat taggtaaaac aaataaaaca
    24361 atacttttaa aaagaggatt atctgctaca attgaagagt ggctaatgtc agcagagtat
    24421 ataatggctg gaggaaatga aaatgtagtt ctttgtgaaa gaggtataag aacttttgaa
    24481 acatatacta gaaatacttt ggatttaagt gcaattttag ctgtgaagaa acttagtcat
    24541 ttaccagtta tagttgaccc aagtcatgca gcaggtaaat catggatggt tgactcttta
    24601 tctaaggcag caattgcagt tggagcagat ggtctaataa tcgaagttca taatgaccca
    24661 gcacatgcac tttgtgatgg aaaacaatcg attaagccaa atgaatatga tgaattgata
    24721 agtgaattaa agactatcgc atcagcagtt ggtagagaaa tataatctat aaaaggatgg
    24781 ttaaacgtgg aagaaaaact attagtaaat ttaaaagaaa atagctacaa tatatttatt
    24841 aaaaaaaata tactaaagaa tataggagaa gaaataaaaa aaatatattt tggaaataag
    24901 atttttattg taactgatga aaatatagca aaattatact tggataaagt aaaaaataat
    24961 ttaagtgaat ctggatttga aattaaatct ttaatattaa aatctggtga agaaacaaaa
    25021 tcatttaata ctcttcctaa aatatacgat agtttacttg actttaagtt aactagaaaa
    25081 gatttgatta ttactttagg aggaggggta ataggtgatt taggtggatt tgcagcagca
    25141 acttttttaa gaggtataag ttttattcaa attccaacat ctttattagc acaagttgat
    25201 agttctgtag gtggaaaagt tggagttgac cttgagagag gcaaaaactt agtgggaagc
    25261 ttttaccaac caaaggctgt gtttatcgac ccaaatgtat tattatcact tccagaaaaa
    25321 ttctatagag atggaatggc agaagttata aaatatggat gtataaaaga caaaactttt
    25381 ttcaataaac ttttaagttt aaaaaataga gaagaagtaa tgcaacatat agaatacatt
    25441 atacataaat gttgctttat taaaaaaact gtagttgaag ctgatgaaaa agactttgga
    25501 gatagaatgc ttctaaactt tggccataca ttaggtcatg ctattgagaa atactacaat
    25561 tttacgggtt atacccatgg agaagctgtt gccataggaa tgtataagat aactttagaa
    25621 agtgaaaaga taggaattac aaaaaaaggg acatcagaac ttataaaatc aattttaatg
    25681 aattataatt tgccttatga gattgaatta agagataata aatctatagt agatgctata
    25741 tctcttgata aaaaaaatct aggtgataca ttaaaaataa tacttttaaa agatattgga
    25801 gagagtatta tatataatac tacttctaaa ttttttcagg aggtaagata atgggaagtc
    25861 taaaaatata tccaagtaaa ttatctggag atgtaaaaat accaccatca aaaagtatgg
    25921 cacatagggc agttatttgt tcatctctaa gcaatggaaa aagtagaatt tctaatatag
    25981 atttttctga tgatataata gctactataa gagcaatgac atcattagga gctattatag
    26041 aaaagaaaga agatatttta gaaatttcgg gaattttttc taaagaaggt attttaaata
    26101 gagagaatca gttgaatcaa cctaaattga caatagattg taatgaatca ggctctacat
    26161 tgagattttt agtacctata tctttagcat ttgatggtgt aaaaaggttt ataggtagag
    26221 gaaatcttgg aaaaagacca cttgatactt attatgagat atttgacaga cagaatataa
    26281 aatatagtta caaagaaaat cagttagatt tgattatatc aggtaagctt aaaccagatg
    26341 aatttagagt aaaaggaaat ataagttctc agtttatcac aggtttactg tttatattgc
    26401 ctacgctaga gagtgattca aagataataa ttactactga gctagaatct aaaggatatt
    26461 tagatttaac tctttcaacg ataaaagatt ttggggtaga aattataaac aataactata
    26521 aagaatttat tataaaagga aatcaaacgt ataaagcgag agattataaa gtagaaggag
    26581 attattctca aggagcattt tatttatcag cagatgctat aggagaagat attagcatat
    26641 tagaccttaa agaagattct cttcaagggg atagtgaagt agttgaaatt ttatctagga
    26701 tgggaatgga aatattaaga gaaggcaaca aaataaaagg aataacaaat ggtttaaatg
    26761 gtactttgat agatgcatct caatgcccag atataatacc tgtattatct gtagtagcat
    26821 ccttaagtat agggaggact acaataatta atgctggtag gcttagaatt aaagaatgtg
    26881 atagacttca tgcaataaat gttgagttaa ataaacttgg agcaaatata gaggagaaag
    26941 aggatagttt gataatcgaa ggagtaagca agttaaatgg tggagtagag gtgtggagtc
    27001 acaaagacca tagaattgct atgacacttg caattgcttc ttgtagatgt gataaaccaa
    27061 taatattaaa agattttgag tgtgtatcaa aatcttatcc acattttttt aaagatttta
    27121 agatgttagg aggtcgaatt gatgagtgga atatggggaa ataatttaaa agtatcaatt
    27181 tttggagaat ctcatggaaa tgctataggt ataaatatag atggtcttcc ttcggggatt
    27241 gaacttgacc ttgataatat tgataaagaa atgaagagaa gagcacctgg aaaaaattct
    27301 atatctactt caagaaatga aagtgatata ccagaaattc taagtggata ttttaatgga
    27361 agaactacag gaacgccatt atgtgcaatc ataagaaata gtgatactcg ttcaaaagat
    27421 tatggagagc ttaaaaactt aatgagacca ggacatgcag atttcacagg taatgtgaga
    27481 tattctggat ttaatgacta tagaggtgga ggtcattttt caggtaggat aacagctcca
    27541 ttagtatttt gtggggctat atgtaaacaa attttatcac aaaaaggaat agagatagga
    27601 gcacacataa aaaaaattaa aaatatagaa gatatgagtt ttgattatgt aaatatttca
    27661 aaacaacagt tatcaaattt gcaaactttg gaactacctt tacttgattt atcaaaggaa
    27721 gaagccatga aaaatacgat tatagatgca aaaaatcaag gagattcagt tggtggtata
    27781 attgagtgtg cagtagtagg tattaatgta gggcttggaa atccattttt tgactctgtt
    27841 gaatctactt tatcacattt attgttttct gttcctgctg taaaaggtgt agagtttggt
    27901 ttaggttttg aacttgcaga tatgtatggc tctcaaagta atgatgaaat gtattatgaa
    27961 ggaaatcaag ttaagagcaa aacaaataac aatggaggaa ttataggagg gattactact
    28021 ggaatgccaa taattttcaa agtggcaatt aagccaactc catcaattag cagacaacaa
    28081 aacacagtta atataaaaga taaaaaggac gatattttat atattaaagg cagacatgac
    28141 ccttgtatag ttcaaagggc tatacctgta atagaagcag taacagccat tggaattttt
    28201 gatttgatga aaggacgata ataatggagg atttaacgag atatagaaat gagattgaca
    28261 atatagataa agagcttatt caattatttg aaaagagaat gaatacagtt cttgaaattg
    28321 ccagacataa aatgaaaaat aacactacta tacttcaaaa agatagagaa gaaaaagtac
    28381 taagtagagc cgtagataat ttagataata aagcatattc acaagaaacg gtacagtttt
    28441 ttaattctat aatggaaatt agtagaggat tacaaaaaag atttatagat aatgatggtg
    28501 agcagaaaat cgagtttagt ttagattcat caaataagaa ttttgatttg tcaaatgtaa
    28561 ataaatataa gtctttaaaa gatgaattaa ataaaaaaaa tatcctagta ggctttcctg
    28621 gaaaatcagg ttcatttaca gaagaagcac taaataaatt cttcaacaaa aaaatatcaa
    28681 aaaaacaatt taaagaattt gaagatgttt tcatagcact taaaaataaa gaaataaact
    28741 atggaataat ccccatagaa aattcatcta caggagctat ctctgaaact tatgaccttt
    28801 tgagaaagta cggtttttat atagttggag aagaatgtat aaaaatagac caaaatttaa
    28861 tagggataaa agacacaaag cttgaagata taaaagaaat atattctcat ccacaaggta
    28921 taggacaatg tagtgaattt ttaaaacaaa atagtacatg gaaattgata ccatttaata
    28981 acacagcaac aagtgcagaa cttgtaagaa aacttcaaga taaaacaaaa gcagcaattg
    29041 caagcaaaaa agctgcaagt atttatggat tagaaataat aagtccttgt ataaatgata
    29101 tagcaaacaa ctatacaaga tttgtagtaa tcagtaatca aatacacatt gaagaagaat
    29161 caaacaaaat gagtgtagta ttttctgttg aacatgaagc aggaaaactt tataaagtac
    29221 ttggatactt tgctaaaaat aatataaata tgacaaaaat agaatcaaga cctatgaaaa
    29281 atgcctcatg gagatatttc ttttatatag attttgagtg ttctatatac aatgctaaag
    29341 tgtacgattt attagaattg atagaacata atacagcata ttttaaattt atgggagtat
    29401 ataaaaataa aactgaatag ataagataaa tttttattta atttataatt attaggaggt
    29461 gtaagtatga attttttcgg tctagtaggt gaaaaactct ctcacagtgt ttcacctcaa
    29521 atccacaaga gagtattcga gatattgaat attgaaagtg cttataaaaa ctttgaaatt
    29581 tcaaaagaag atatatctaa gctagacggt gctataaaat tattaggaat acaaggggta
    29641 aatgttactg taccatataa ggagcgtatt atgaaatatc ttgattttat atcaccagag
    29701 gcaaaacgta taggagcagt taatacaatt ttactcagag aaaatatgtt atatggttac
    29761 aatacagatt actttggtct tgatagtatg tttaaaatgg ctaatattga tgttcaagga
    29821 aaagtagcag ttatattagg aactggaggt gcttctaaag ctgctcttac atattttatt
    29881 gattctggta tagaaaagct ttatgtttca actagaaaaa aggatgataa aaaattatta
    29941 aatagtaaag ctatattaat agattatgaa gaacttaaac atataaaagg agatataata
    30001 ttaaatgcta caccagtagg tatgtaccct aatgtaggaa tttcaccagt gtcaaaatct
    30061 attatacaaa attttgatat attaatagat ttaatttaca atcctggaga aacagagttt
    30121 ttaagaattg gtaatagtat gggtaaaaaa acttgtgatg gattatatat gctggtgggg
    30181 caagcaataa aatctcagga aatttggcaa gatactaaaa tagataatag tattttagat
    30241 gttatatata atgaactaaa attagaattt ttgtaaggga gattgttatg ataaataaaa
    30301 caaaagaaaa attgatatta ataggtatgc caggtagtgg aaaaactaca attggtaaac
    30361 ttttggccaa agaatataat tgtagtttct gtgatatgga tgattatata attcaaatat
    30421 ctcaaaaaag tatagcagag ttgttttcag aaggagaaga tatctttagg aactatgaga
    30481 ctcaagcatg tagagaactt tctataagtg ataaaacagt gatatctaca ggtggaggtg
    30541 taataaaaaa ggatgttaat atggaaatac taaaagaaac aggtataata atttttattg
    30601 atagacctat acaaaagatt ttggaagata taaatattaa ttcaagacca ttattaaaaa
    30661 acggaaaaga tagattgtat aatctttata atgagagaat aaatctttat aaaaaatttt
    30721 cagatataga gattttaaat gataaatcat taaataatgc tgtatataat attacaaatg
    30781 cagtcagtga aaattttaaa tttgacttta aagaaaaata atctaggggg aagtaaaaat
    30841 aatgaatatt gttattgtag gactaggagt tataggaggc tcttttgcta aagcattaaa
    30901 aaaagctgga tatgaaaatg tatttggagt agatgtagat ttagaaactt taaaaaaagc
    30961 agaaaaagca aaaatcataa aaaaaggatg tactacaggt aaagagttat ttaaaaaagc
    31021 tgatttaatt atactatcta tatatcctag attagttgta gattttctaa ataagaataa
    31081 aaactttttt aaaaaaggga ctataattac tgatactaca ggaataaaag aaacacttat
    31141 caatgatgtg ttgcaaatta ttccagatga tatagatttt atatttggac atccaatggc
    31201 aggtagggaa aaaaagggta ttgattttgc aagtgaacaa gtttttaatg gtgcaaatta
    31261 tataattact ccaactggca gaaacaacat aaaaaattta gagttagttg aaaatttaat
    31321 tttagagatt ggatttaaaa gagtaaaaaa gttaacttca caaaaacatg atgagattat
    31381 agcttttact tctcagttac ctcatgttat ggcagttgct cttataaata gtgatgaaga
    31441 aggtagagat acgggtaaat ttattggaga tagttataga gatttaacta gaattgcaaa
    31501 tatgaatgaa gacttatgga gtgaactttt tttaggaaat agagataatt tactaaaagt
    31561 tatagaaaac tttgaatcag aagtaaattt agtaaaagaa gctatattta acaatgataa
    31621 aaataaatta atagagtatt ttaaaaaatc atcaataaga agagaagctt tagaaaaata
    31681 aatattaata tttaagctat atatagatgg gtataaatat aagcgatagt gtatttaatt
    31741 gtattaataa atatggattc aatataatta aatatgctat tgatatattt gtacccttaa
    31801 ctattgttat cttttaaatg ataatgatat ttatttaaat actctttatt aacaatttat
    31861 aaaacttaat tgtaaaaaat acttattaat agtaaaataa agtgaatcaa ttatattata
    31921 attgctaaag agagtgaggt gtagctattt gaaaaaaaat agattaatag caaagaatat
    31981 atcaatagca tttatagtac tattcttttt tagtgtattt acattttttt atgtaggtaa
    32041 tattaataga gtgttagaat atgaaacaaa tgacataata acagttacaa ttgctggatg
    32101 gattatactt tcatttttat ttttaggtat tataatttac atattatatt caaaagcaaa
    32161 tagtcaaaaa actatagaaa aagtagcata tacggatttt gtaacaggtt attccaactg
    32221 gagaaagttt gaattagatg ttacaaattt attaaagaaa acatcacaaa ataataaata
    32281 tgcaatggtc atattcgata ttgataaatt taaagcaatt aatgatatat atggccataa
    32341 aaagggaaat ttaatattaa aagatattgc agatacttta aatgaattga ctgatatcaa
    32401 tgaaactttt gctcgtgtaa gtgctgataa tttcaatata ttattaacat ataacaaaaa
    32461 agaggatata ataaatatta tcaaaaagat tatggcaaat aatgaacttg taaacttatc
    32521 ttttggaatt tatgaaatca aagataagga tttatctgta agtgtatata gtgatagagc
    32581 ttcacttgca aaatcatcaa taaaaaataa tagtgatgta aattttgcat tttttaatga
    32641 caaattaaga gagaaattat tatttgaaga taagatagaa aaagaaatgg aatatgctct
    32701 tgaaagtggg caattcgtaa tgtatttaca accaaaatac aatattaaat tagataaatt
    32761 ttgtggaagt gaagccctag tcagatggca atatacagaa aaagaggtca tatatccagg
    32821 tgattttatt cctatatttg aaaaaaatgg atttattaga aagattgata tgtacatatt
    32881 agaacaagct tgtaaagaaa tccggtcttt atttgataaa ggaatttcac ctttacctat
    32941 atctgtaaac ttctcaagag ttgatttttt taaaaaagat tttattgaaa acatagtaaa
    33001 tatatgtgat agatataaaa taccatatag tttaatagaa attgaaatta ctgaatctag
    33061 tatgtttgga gatactgata ctctatttaa tgttagtaga aacctacagg atattggctt
    33121 tatagttgca atggatgatt ttggctctgg atattcttct gtaaatatgc ttaaaaatat
    33181 accattaaat gtaataaaat tagatagagg attttttgtt gatgataaag atgttgataa
    33241 gagtcaaatt gttataaaaa gcatagtttc tctcattaag caattaggaa taagggttgt
    33301 tgctgaagga attgaaacaa gaagtcaaat agaaatgtta aaaaaagcaa attgtgatat
    33361 tgttcaagga tattattttt caaaaccatt accaattaaa gaatttgaaa aattagtcta
    33421 taaaatatag tcagcgagtc ttaaatggga ggtggtgatt aagtgataag agcaaaatcg
    33481 ttaaaaaatg tactgagtat tgttttaata tttttattta caataatttc tttttctgat
    33541 tttgcattta aaactaatgt ccaggaagaa gaaaatagta aaattaattt aagagaaata
    33601 tccctacaaa gttccaatgc tataaaaata aaattagata gttctctatc ctttattaaa
    33661 agtgtggcaa atatggtttc ttattttaat actatagata actcaaaaat agttccatta
    33721 ttagctaata tatcaaaaga atctgacttt caaagaatct ctattgtatc tcctgatgga
    33781 ataagtcata ccagtgatgg caaaattatc aatgtgtcaa agtatcagta ttttaagaaa
    33841 gctattaaag gagaaagtaa tatatctgaa gttgtgaaat ctccaattga tggaaaagat
    33901 acttttgtta tagctactcc tgtatttaat aagaataaca aaataattgg tgttttatac
    33961 ggttcttact acaatgataa attagctgaa tttatagata taacaagttt taatagtgaa
    34021 gggtacatag atatatttga atctagtggt caatttgttt taaaatcttc acatacaaac
    34081 aaactgatta agtcaagtag taacatatat gatatattta aaaaagcttc ttttgatgat
    34141 ggttatagct ataaaaaaat atatgaagat acaaaaaata acaagagtgg ctttacctca
    34201 tatgaataca aaggagaaaa tcgttatgct acttatacac ccattggtgt aaatgactgg
    34261 tatgtaattt ctgtgatacc acaatatact gtaagaagaa acattgataa aataaatcaa
    34321 ttagcatttt ctcttatttt caaggtattc ttattgttta ttatgcttat aatatatatt
    34381 atttataaaa acaataaatc tcagaaagat atactaaaag ctaacaaaga aatctcatct
    34441 attacaaata gcattcctgg aggagtacaa aagtgtaccc tgggtgagac atgcaatatt
    34501 aattttttaa gtgatggatt tatagagttg tttggttata caagagaaga aataaaaaca
    34561 ttgtttaata atgattttta tagtttaata cataaagatg atgttgaaag aataaaaaaa
    34621 gaaattttta aacaacttta caaaaataaa actgttgaat tagaatatag gattataaca
    34681 aaaaatggta atacagtatg ggttttagat aaaggggagc ttataacaga acctgatgga
    34741 aaagagtatt tttgttgtgt aactgtagat attactagaa caaaacaatt agaacaagag
    34801 atggaacaaa aaaatctaga acttgaaatg atatcagaaa atgttttagg tggtataatt
    34861 ataacagaat ttaatgatga ttttactata aaatacgcta actctggtta tctttcaatg
    34921 attggatata cacgtgaaca attagaaaat gaacttaaat acaaagcttg taatcttgtt
    34981 ttttatgaag atagaaagaa ggctcttgaa agtatacaac atcaattaaa cacaaaagga
    35041 atagctgtat atcaacatag aataagaaga agagatggta atattatttg ggtttctata
    35101 aaaggaaggc ttattgttga tgatgatggt attgaaaaag gtatttggat tctaaatgat
    35161 ataacagatt taaaaaatgc agaacaaaaa cttaaaataa atgaagaaag atttagaatt
    35221 gcattaaagc aaacatcaaa cactatattt gagtatgata taaaaacaaa gtcactttta
    35281 aatactagta aagagcttga taaatataat atttataaaa ttactaaaaa tgttccatat
    35341 tctctagtag aatcaggagt tattcataaa gattttagtg atgattttat aaacatgtat
    35401 gaaaatgtaa taaatggagc aaaaaaagca agttgtgtag ttaagatgaa acttccagat
    35461 gaaaattata tatggaataa agttaccttg actactattt ttgatgaaga tggtaatcct
    35521 gtaagagcaa ttggtataca ggaagatata agcaaacaaa aggaagcaga aataagatac
    35581 aatcaagaag gtaagtatca ttcagctata ttgtcggaag caatgataac ctatgaaata
    35641 aatgtatcaa aggatacttt tatcaaagga aatgaaagtt ggcaaaaacc atttggaatt
    35701 aagcctgaca ataactattc tcaaatggta aaaactatag caaatagtat tgtacataaa
    35761 gacaataaag aaacattttt aaatacattt ttatgtgaaa acttattgga tgcatataaa
    35821 aataatgtga ctgaaataaa attagaatat caaagaatga atcaagaaaa taaaatgatt
    35881 tgggtcattt gtacaatgca cttaataaaa gattctatta cgaacgatat aaaagcactt
    35941 gcttatgtta aagatattga caagcaaaaa aatgaagaaa ttagattgaa attaaaagct
    36001 gaaagagata ctcttacagg attatataat aaaggtacta cagaaaaatt gattaatgat
    36061 ttcttgaact ctgaggaagc aagcttagga atgcatgcat ttttaattgt tgatatagat
    36121 aattttaaat ctgtgaacga taatttagga catgtatttg gagataaagt attatttgaa
    36181 gtttctaaaa acctaaaacc tatatttaga aaagatgata tagtaggtcg aattggtgga
    36241 gatgaattta tagtattctt aaaaaatatt cagtcttttg agaataccaa aaagaaagca
    36301 gaaaaaatat gcgatatatt tagaaattct tatacggaaa ataaaaagac atataaaata
    36361 tctggaacag ttggaatttc atttgtacca gaacatggaa ctgtatttga agaactttat
    36421 aaaaaagcag acatagcact ttattatgca aagagcaaag gaaaagataa gtatgcactt
    36481 tataatgatt gtatctacca aaatggactt gaaaataata taagtgataa taatataaaa
    36541 ttagcagata aatgtgagaa atccaaacca gtacttaaag aaattcttga ttctattgat
    36601 aattatatct atatagtgaa tccaaatact tatgaacttc tttttgtcaa taataaggtg
    36661 tctcgtttgg atttagagat aaaattagga gaaacctgtt ataaatcact attaaaatct
    36721 gatagaccat gtaataattg ccctcttaac ggattagaag aaaataagca ttcaaaattc
    36781 aaaatagaga caaatacatt tggtaaaaat atcagtatag caagttggat taattgcata
    36841 gatggagaat acaactgtct tatagagtgt atagattctt ctttatacaa aaataaataa
    36901 aaaaggacta tgaagatatg ttaaatagta taactttgat acttggtata atatttacaa
    36961 tttactattt ttatctcaaa atagtttttg gaggaatttc atttagtgag attttcttag
    37021 ttgtaggaat tgtactaatt atctatcaaa tatttaagaa aaaaattaaa gaaaagaagg
    37081 ttttttatag ggtgttaaaa ataataatca gcattttttt aatagtattt gtagttactg
    37141 agagtctaat tattttttat cctaaaaata gtttagaatc aaaaagtgat tatctcttaa
    37201 ttttaggagc ttctgtaaaa aagactacac caagtacaac cctgaagggt aggttagaca
    37261 ctgcattgaa atacctaaaa attaatgata attgttatgt ggtagtatct ggtggtaaag
    37321 gaagtggaga aaaaataact gaggcaaaag ctatgaaaga ttatcttata aaaaatggta
    37381 tagataaaaa taggataata gaagaggata aatccacgaa tacttatgag aattttaaat
    37441 attcaaaatt gaagatagaa gaacatagtc aaagaaaact aagcgattta aaagtaaaaa
    37501 tagtaacaac agattttcat gttctcagaa gtaaaatatt agcatataga aatggatata
    37561 aaaatacgtc tttttatgca aaactttcat ttgtaccaac ttattataca agagaatttt
    37621 ttgcattatg gaaaacaatc atttttgata gataataaat aaaaagacta gatataaact
    37681 catatctagt cttttctatt cccttaattc taatccattt tccaacttta cttgttgtag
    37741 aaatttcaac attgggattt acaagtaatt gcttataaga agttttatat tttacgattc
    37801 caaaatataa ttttccttca taatccatta taaatccgaa tggtcttact cttggtttat
    37861 tatcttcaac tgtagcaaaa tagaatgttg agttttcttt aaaaaaattc attatttttt
    37921 tcatgattaa atcctctttg tatcttatac taatataatg aatataaata aaatattcat
    37981 aatactaata taaatcgata taaaaacaat tacaatatta tattgattat tcaaaattat
    38041 atataaaatt cagaaaaaaa ttagtttaca taataaaaat aaagtcaact aaaattattg
    38101 attttagatt aaagtaccag attaagcgtt taagtagatt ttaagcttga tttgattaga
    38161 aaggtacaaa ctatcgccga aaaaaattaa acccatttaa aaagcaatat aaaagcttgt
    38221 tatttttgag aaaaatagac cctctaaact caattagata aaaataaaat acagaaaatt
    38281 atatctctga atatctcaag taattaattt taaattttac gatattttgt ttgatgattt
    38341 ataatataaa agcatactct taatctgctc aaattaaaaa gaataaaaaa taacaaaaaa
    38401 atcactgaca tttcactgac aaattgtaat tttgttatta taaatacatt gaaaatactt
    38461 gattattgaa aaatggcata aaataataca ttttatgcca tttactatta tttgatagtt
    38521 tttaacttat gacataagat attttttaac atatacaata aaatataaaa aattgatatt
    38581 acaaataaaa aaaatacata ttagatgtta tagaaaaaaa gcgcacttat aggcttaaaa
    38641 tgtcacataa aagagtttta aagaataata tattatgaac acaaattttg taatcgcaaa
    38701 ggagtgataa tatggcaaca gtatcaggac aaatagtttt tgatagaaat agaagtgcta
    38761 ccattgattc tggagactca ggaatagcca atataccagt tgtattacaa gatatagcaa
    38821 ctggagttag acttgtggtt ctcacagatg catcaggaaa ttatgttttt actaatgttc
    38881 cagatggtaa ctatagaatt gtagaagctt ttggaactac aggaggagta ccaacaccag
    38941 gggattttgc aacagcgata gtaggtccag ttccaattgc agaaatgcca cctattagtt
    39001 ctgtgacaaa tcctcctatt ggttcaacaa acttagatgg tacaacacct aacacactat
    39061 taataacagt agcaggttca gatataacaa atcaaaatat attaaatggg cctgtgattt
    39121 atacacctat agagaatata ttggattctt gcgtatctgt atctaatata aaccttatta
    39181 cagatgcaga taacggaaca ttcggttttt ttccaccagg tacaccaagt aatacaggac
    39241 ctgaaataga accttaccca aatgtgacgc cagattttac gtatgttgta ccagacccaa
    39301 ctaagtttac acctttagat ggagaatata cagtacaaaa tattatgaca aatgcaatga
    39361 gtaatgttat aggagcttgg tggcgtattg ctgaccatac tacaggaaat gaaacaggaa
    39421 gaatgatggt ggtaaatggt tttaatcctg gagctgtatt ttttaaatca acagtacaag
    39481 ttacacctaa cactaattat ttatttagca cttggatttt aaaccttttt aaggtaacag
    39541 gatatccacc accacagcta ggtgtaagaa tatttgacca aaataataat atactatatc
    39601 aagcaacatt aggagctcaa attccagtta atacaaacgc accagaatgg aaagaagtag
    39661 gtactgtgat taattctcaa aataataatc aacttacagt agaatttttt agtgaaggag
    39721 aaagcgccat tggaaatgac tatgctatag atgatgtttc tttaagagaa atagctgttc
    39781 caacttttac tccaataaaa acaagtaaca cagaaactgc taatgtaggt gatataatca
    39841 catatacagt tacattagat aatacttgtg atagcccttt aactaatgta ttttttaggg
    39901 atttaattcc aaatggttta gagtttatac ctggaactgt aacggttgat ggagtatctg
    39961 taccaggagt agaccctaat acaggtttcc cacttccaga tattggagga ggaacagggg
    40021 ttgaagtaac ttttgatgtt gtggttgaaa gtattcctaa cccaaatcct actaataata
    40081 tagctaatat agattactcc tatacacctg tagaaggcgg tataccaaat gatttttcag
    40141 tagattctaa tccagttcct gttgaagtaa tatcagcaga tattgaagtt acaaaattat
    40201 ctgaacctac tatagtgaat ccaggagagg aattaatata cactataaaa gtagtaaata
    40261 atggaccatt cccatctgaa aatgtggttt taacagatga tgtaccagct tctattgtaa
    40321 atccagagta ttcattagat ggaggagtaa cttttcaacc atggactgga agtttaaata
    40381 tagggacatt agaagtagga gagacaagag ttattataat taggggtatt gtaaatccat
    40441 caacagtagg aattataaca aatacagctg tagtatcttc aactacagca gacccaaacc
    40501 ttaataataa tgcatctaca atagagacag aagtgaattt attagcagat attttagtaa
    40561 tgaaaacagc agaacctaat tcagctgttc caggtacttt attgagatat actattcaag
    40621 tagaaaactt aggaccagca aatgctgaaa atgtaatatt aaatgatgat attccagctt
    40681 ctattataaa tccagaatat tcattggatg gaggagcaag ttttcaacca tggaatggaa
    40741 gtcttaatat aggtacttta aactctggaa tttcattaac agttttaatt caaggaacag
    40801 ttagtttaaa ttcttcagaa tatatagtaa atacagcaac agtttcttca actacacctg
    40861 acccagattt aagcaacaat atatctacca ttattacacc agttaaccca caagcaggta
    40921 tttctattat aaaagtagct gacgaggatg tagctgttcc aggagaagaa tttgtatata
    40981 caattgaaat ttttaatgaa ggaccatcta atgctacgaa tgtagtttta acagatgata
    41041 taccagatgt tattttaaat ccagaatatt cattggatgg aggagcaact ttccaaccat
    41101 ggactggaag tcttaatata ggtacagttg caccagggca attaataaga attatcataa
    41161 agggattagt aagttcaact gctacaggag atattactaa tacagcagaa gtaagtgcag
    41221 atgtaccaga accagttacg gattcatcaa cagtgacaac tcctatagtt ccatcagcag
    41281 atatagaagt aataaaaact agcaatatgg atacaacagt tccaggagaa actttcagtt
    41341 atactataac agttacaaat ttaggaccat ctgctgcaca aagtatcgtt ttgatagatg
    41401 atataccaga tgttatttta aatccagagt attcattgga tggaggagta actttccaac
    41461 catggaatgg aaatcttagt ataggcactt tggatgctgg agaaataaga agtattataa
    41521 taagaggaac agtgagccag acagcagtag gtacaattat aaatacagca acaataagtt
    41581 caactacacc tgacccaaat ccagataata atacttcaac agatgaaaca gatataagtc
    41641 cattagcaga tatttctgtg ataaaaggca acgaaccagt tgctatacca gggggaagat
    41701 ttatttatgg aattgaaatt gcaaatgcag gaccatcttt tgcagagaac gtaactttaa
    41761 cagataatat accagcttct attttaaatc cagagtactc aatagataat ggagtgactt
    41821 tccaaccatg gaatggaagc cttaatatag gtactttaga tgctggagag ataagaaata
    41881 tcataataag gggaacagta agtcaaacag caataggcac aattataaat acagcaacag
    41941 taagttcaac tacacctgac ccaaatctaa ataacaatac ttcaacatca gaagcagagg
    42001 taagttcatc agcagatatt tctgtagtaa aacgaagcaa tcagactgtt gttgtaccag
    42061 gagatgtact agactataca attgaggtga gaaatgcagg accgtctact gctcagaacg
    42121 taactttaac agataatata ccagcttcta ttttaagtcc agaatattca atagataatg
    42181 gagtgacttt tcaaccatgg actggaagtc ttagtatagg cactttagat gctggagaga
    42241 taagaaatat tataataagg ggaatagtaa gtcaaacagc aataggtaca attataaata
    42301 cagcaacagt aagttcaact acacctgacc caaatccaga taataatact tcaacatcag
    42361 aaatagatat aagttcatca gcagatattt ctgtaataaa attagcaaat aaaacagaag
    42421 catgtgtagg agagcaaata gattttgtaa tagtagtatc aaatgcagga ccagaaaatg
    42481 ctcaaaatgt tactttaata gacaatgttt cagataagct taagaaagca gtattttcac
    42541 ttgatagagg tgtaagtttt caaccatgga ctggaagtct taatataggt acactaccag
    42601 ctggaacttt aagagtgatt ctattaagag gaattataaa atcaacatgt cttgatagat
    42661 taacaaatat tgcataagtt acttcaacag caccagattc aaaccttaac aataatatat
    42721 caagagtgca agtagaaata aaacaatgtt gttgtaatga ttgctgttgt aacaactgta
    42781 gtaattgctg ttgcaatgat tgtggttgta aagattgtta ctgtaattgt tgtaaaaatg
    42841 acttttggtg ttgattttat aaaataattt tgtatacctt aaattaaact gaaataaaaa
    42901 ataaattcac atatgagtaa aatattttat aaatattaat aaattttcta tctttgatat
    42961 ggaccacatt cgtaatacta gttattaaat gaagtggtcc tttttaattc attaaaatta
    43021 tttattctaa ttaaatttta aatgtattaa ataattttaa ttttttataa aaaatattg
//
LOCUS       DAMJXI010000030        42229 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.032, whole genome shotgun sequence.
ACCESSION   DAMJXI010000030 DAMJXI010000000
VERSION     DAMJXI010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42229
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.032"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            42..1898
                     /locus_tag="PC465_002056"
     CDS             42..1898
                     /locus_tag="PC465_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HDF2649350.1"
                     /translation="MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKV
                     LQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIIGDSY
                     IILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGIYIDCSENLIPILNNNIKTTKDIFG
                     KNDIEVWGENTGKLFRDDYREGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTI
                     GIVDNIIYSGYSNRNYNSKDLMKMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKE
                     ELLGKNSYKISEEEALIDKIFESDKGVVENKKVVTFELNISMNDENKCIEITKRPFFD
                     SYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKE
                     ADLIESNDTLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEI
                     CMSVADFASQNNIQLTFDTEIEEFSMLFDSEKLERIILNLLSNGIKYNKKDGKINIFL
                     YVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVKSLVELH
                     EGSISLKSQLGIGSEFIVSLPVRSKNNIEKYNHKREISNELSKKLEIEFSDL"
     misc_binding    1981..2221
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    2287..2522
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            2607..3824
                     /locus_tag="PC465_002057"
     CDS             2607..3824
                     /locus_tag="PC465_002057"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HDF2649351.1"
                     /translation="MENKVKIGVLGYGVVGSGLIDIIDNNKEKRNIEIVGILVNNLEK
                     HKDKKYSNIITNNIDDIFNKDIDILVEVMGGLEPSLSYIKKALNNKIHVVTANKDLLA
                     ECGDELAKLASENKVSIKFEASVAGGIPVLKPIIESLEGNNIDSINAILNGTTNFILS
                     KMYDENLSYDMALRQAQELGFAEANPESDVLGYDAARKLSILSTLAYDNRVYWKDVYL
                     EGITDIDEKDIEYAKKLNCKIKLIGQSKYENDKVSAFVRPVLVEKDNILARIDNEFNA
                     VIVNGDSVGEVSFVGKGAGSLATGSAVYSDVIDIIDNRVSSIDSFTKDKIQVNKIVRE
                     KCGALLRFKKCNKDEILNIVENCLVKFDILNDDDELAIMVYADSEYEINNSLCLIKDK
                     GYCEKMNKMLKIS"
     gene            3941..4423
                     /gene="cdeM"
                     /locus_tag="PC465_002058"
     CDS             3941..4423
                     /gene="cdeM"
                     /locus_tag="PC465_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeM"
                     /protein_id="HDF2649352.1"
                     /translation="MENKKCYSEDWYERGESTAKWFQNDREEYEREAYDEDRERRGSN
                     CGCSDSGENRPRNCERFRREAEIREREAREAFCESSEKKKEALAYECEARKLWEEAEK
                     YWDEYSKYNYKGIEYLAEAARLFDEGMECEARRNGNNGGNNNNCCHKCHKCNCNCCRK
                     "
     gene            4688..5953
                     /gene="hisD"
                     /locus_tag="PC465_002059"
     CDS             4688..5953
                     /gene="hisD"
                     /locus_tag="PC465_002059"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HDF2649353.1"
                     /translation="MKSIKTSSMKEKVDEKILREQVSSIIEDIRNNKDVALKKYNEKF
                     DRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIREFAKAQKLSFENPFEKEIYP
                     GVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTMKNTEKIN
                     PKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKINPVDIIVGPGNKFVTEAKRQCYGQ
                     VGIDFVAGPSEVLIIADETSNPVYIAADLLAQCEHDLNARGILLTNSLEVAQKVEKNI
                     ESMLKDLPTKDIAYSSWENNGEIILVDDMEEAIKISNFYAPEHLEVAVNEYNDICDRL
                     TNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEKAI
                     QSLAPVAEKLAKEEGLYAHAKAAEVRFKK"
     gene            complement(6156..6908)
                     /locus_tag="PC465_002060"
     CDS             complement(6156..6908)
                     /locus_tag="PC465_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2649354.1"
                     /translation="MSYFQYQGNSCFYKEYGQGKPIIFLHGNTGSSNMFKALVPLYAE
                     NFRCILIDFLGNGQSDRVSQFSPDIWHDEALQTIALIEHLNCGKVGLIGTSGGAWAAV
                     NTGLERPDLVEAIIADSFDGRTLNDNFIDNLITGREKSKQDIQARKFYEWCHGKDWEN
                     VVNLDTKALLQCANEKRPLFHKELCKLEMPILFTGSKEDEMCRHNLEEEYKQMATFIS
                     KASIHIFSQGGHPAILTNADEFAQLAKVFFNY"
     gene            complement(7026..7295)
                     /locus_tag="PC465_002061"
     CDS             complement(7026..7295)
                     /locus_tag="PC465_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649355.1"
                     /translation="MSYQNSIDLLPKELIEQVQEYIDGKVIYIPKKQEHKKHWGENTN
                     TKQVLASRNSQICINFQNGMSIKQLSEKYFLTEKSIQRILKQQNL"
     gene            7770..8864
                     /locus_tag="PC465_002062"
     CDS             7770..8864
                     /locus_tag="PC465_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDF2649356.1"
                     /translation="MKNIVGKPQTIKKVNEDLIKNIIKNEGPITKPEISSITELSLAT
                     VNKIVEQLALKNEVKVSGLSESTGGRRAQLFEINANLEHIIALYYYRNCCIGVVANLL
                     GEIIYQEEFNIRMDTYENVNQDTFFVIDTLIKREKGNNIRAIGIGVPGVVKKGVVKNI
                     PTIKSWEGINLENLIKSKYNTKVFIENDTNITTIGIYQKQYKDKYKNMALMYLEDGIG
                     SGIVINGELYLGSTNFAGELSYLNIEFGKYNSNNLNLEDYIMSLRKRYLESKDNKFKK
                     EILSIISNFIRTLVCVLNPQAMIIQCSILTKSDMEFIEKDVSNNVGEENFPKLIKVES
                     LREGSINGVISMCLKETDYQYSLSNKKGGY"
     gene            8866..9816
                     /locus_tag="PC465_002063"
     CDS             8866..9816
                     /locus_tag="PC465_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HDF2649357.1"
                     /translation="MKYLVSIDGGGTKTKFCVSDLDGNILKEHTTGSTNYKSVGIKKT
                     YENINNGFKKILKDLYIDYDDIEYTVFGISGCDSPNDYKIIMDEILKIGINKEKIYLA
                     NDAVLAFYAQADSPGLVIVAGTGSIILGIKEDGEIYRVGGWGYNFSDLGSGYDIGRKL
                     LKKVLLYCDECHEYSDLFSCVLDFFGANSFEQLAYMITDINDNVEIANLASLVIDCAE
                     QGDKLAIEILRESSTELSKLAQVILRKISNPMKMDKSEINIVLSGGTLNKTVYAQMLM
                     NNLKTENTDKNLKFISQENQPVYGGIRLAMALANRRAKHG"
     gene            9809..10993
                     /locus_tag="PC465_002064"
     CDS             9809..10993
                     /locus_tag="PC465_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649358.1"
                     /translation="MDRKKVIVQIFTGGFKAKEIKFNDIKCKLLELLDCIDIEKVIMG
                     WSVDEELYVETKKLLNKYNVELYLWLPCFSEIGLLEKSNLLIDYMGKEVKGYALQEDE
                     NFEFYCPNNKENIKNIKKIYSTYFSDIKFDGIFLDKIRYGSFSNKLNGVFNCFCKDCL
                     NIYEKNNIDKESLMREMNNVSKGVIDNEDTPFGITEYINGKYKFKNKIWEDFFETKNQ
                     NIYKALLEISNYFKSKGLKIGIDTFSPFISYFTGQDLEKLQEVADFIKPMMYRITKAP
                     AGLPFEFERFIDESIHKNKEIGKRNFLDILGIKEYEGNVYPIEFVLEEIDFMTRNLNK
                     DIYVGVEINKKEIIAPVTPKYISENISNINKTTVKGYVLSWDLLSAPKENIDEIIKWF
                     RN"
     gene            11006..12502
                     /locus_tag="PC465_002065"
     CDS             11006..12502
                     /locus_tag="PC465_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDF2649359.1"
                     /translation="MSKILEMQQIYKSFGKVDVLKGINFELEKGEVRALLGANGAGKS
                     TLIKILGGVHSQTKGKVILTGNEIMFKNPHHSKENGISIIYQELSLIPTLTVLENIFL
                     GREILKGSVFLNKKDMLEEYMKICEDFDFNIDPHIVVSNLSVANQQMVEIMKAVSCNS
                     EIIIMDEPTTSLTNNEKDGLFKIISRLKSKGKTIVYISHILEEVFKVCDSTSIMKNGI
                     MIGTYDVEDLTKLKITQLMTGNDNHKLIEKKDYTFAKYEEPPVLEVKNISWSNKIKNV
                     SFKVYRGEVVGLAGLVGSRRTEIINLIFGIDNKDSGDIFINGKKVDITSPKVAIKNKI
                     GLIPEDRKNLGLILEQAIYTNSSSVQIDKFKKFLFIDRNKEIEFSKKGVKELGIKVSD
                     VKQEVKELSGGNQQKVVVSKWLEKDLDLIIYDEPTKGIDIAAKEDIFNTIKEFSSKGI
                     GVIFISSDLEEVIRVSDRILVTREGSIVDDLKNENIQVQDIMNSIFNV"
     gene            12525..13475
                     /locus_tag="PC465_002066"
     CDS             12525..13475
                     /locus_tag="PC465_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2649360.1"
                     /translation="MKKAFEKLNLRDYGVLLGFLALCIAISIATPSFLGKQNILNLLR
                     QSSIIGIISAGMTFVIISGNFDISVGAVAALAGAITMKFATGGTNLFASMFLGVAICA
                     VIGLINGIVVAKINVPSLIATMAMVTIVRGLLLMLTGGYPITENIPILDYIGNGYLFN
                     IPIPVVIFFIVVLVSFIVLNKTKFGRYVYSVGGNQEASKLNGINVDSHKVKVFIINAV
                     LAGIAGIVLTGRLGTATAIAGEGYDMDAIASVVIGGTSVAGGSGSVLKTVIGVLLMSV
                     INNSFNLLGIDVYFQYIFKGLIILAAVGFDSYSKKKLASR"
     gene            13496..14458
                     /locus_tag="PC465_002067"
     CDS             13496..14458
                     /locus_tag="PC465_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDF2649361.1"
                     /translation="MKKLMKHLALLLSLVMIFGLVGCSNGGDKEKNGEKKIAVLLPGS
                     TGYFVATKQGIDAKSKELGVSVEYADAQWDASKQLSQAEDFMAKGVDMIALCGVDSAV
                     SERIAKAANDSDVPIVAFTNSIGSNPTGEFKGLVTYIGQNEEETGALTGKIAKNLLGE
                     TGGKAVLIEGVPGTTPQVLRKKGLEKELKDSNIEIVYNQTSNWEKEQALKVTEDLIQK
                     KTDFNVIICQDDNSATGAGQALKDAGLKDKVKVIGLGGSKDGLKAITDGLIDGTTYMS
                     AVEEGGLVIEKASKFLKGEKIEPVTQIKQVEVNKDNISEFKGEW"
     gene            14830..15462
                     /locus_tag="PC465_002068"
     CDS             14830..15462
                     /locus_tag="PC465_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2649362.1"
                     /translation="MARRLFLERIGLIFLGSAILAFGVYNFYYLNNITEGGVLGILLL
                     LKNLFNIQPAIANVVIDGLLLLVGYKFFGKKFLIYSIVASITFSVLYDLFEAIGPLVP
                     QSQNMLLSTILAGVTVGTGVGIVVKAGCASGGDDALALVISKTTSLNIGQVYLATDVI
                     VLLLSLFYLSAFDIFYSLIAVTISGKVIDFIYYHGKSLDMDISNDIVPEC"
     gene            15873..15965
                     /gene="kdpF"
                     /locus_tag="PC465_002069"
     CDS             15873..15965
                     /gene="kdpF"
                     /locus_tag="PC465_002069"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR02115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HDF2649363.1"
                     /translation="MEGLPMWFLAVVIIMLIIYLVYALINPEKF"
     gene            16006..17688
                     /gene="kdpA"
                     /locus_tag="PC465_002070"
     CDS             16006..17688
                     /gene="kdpA"
                     /locus_tag="PC465_002070"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015391009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HDF2649364.1"
                     /translation="MFMVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDN
                     FIYKVCSIDKKKEMNWKQYALALLFTNAVMVFIGYIILRTQSMHIFNPSGIKSMEQGL
                     SFNTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGLVGKK
                     KTLGNFYVDLIRITTRVLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGP
                     VAALESIKHLGTNGGGFFGSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKN
                     KKQGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSS
                     LFTTVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVF
                     LCGLMVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAIPAGLEGISNPGF
                     HGLSQVLYEFASSAANNGSGFEGLGDNTMFWNITTGIVMFFGRYVSIIVLLAISSLLA
                     SKKAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHLVLWH"
     gene            17713..19770
                     /gene="kdpB"
                     /locus_tag="PC465_002071"
     CDS             17713..19770
                     /gene="kdpB"
                     /locus_tag="PC465_002071"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010966942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HDF2649365.1"
                     /translation="METKKTKFITKDIFKTSIIEAFKKLNPKYMMKNPVMFVVEIGFI
                     VTLILTIVPSLFGDEGNNLRAYNGIVTIILFITVLFANFAEAVAEGRGKAQADTLKKT
                     RKDTVARVIDTLGNEKMISASELKLGDIVLVNAGEVIPNDGEVIEGIASVDESAITGE
                     SAPVMRESGGDFASVTGGTTVVSDWLKIRITTKPGESFLDKMIALVEGASRQKTPNEI
                     ALNTLLVGLTLIFMVVLISLYPMANYAGVKIPISTMIALLVCLIPTTIGGLLSAIGIA
                     GMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLASEFIAVGNADSKDLIN
                     YSVMCSLKDDTPEGKSIVDLGMKLGSTGKTKEAEEAEFVEFSAQTRMSGINLADGRAI
                     RKGAYDSIIKRVKESGGTVPEDLEENVNRVAKLGGTPLVVCVDNEIYGIIYLKDTVKS
                     GLVERFARLREIGIKTIMCTGDNPLTAATIAREAGVDGFIAECKPEDKIDAIKKEQLE
                     GKIVAMTGDGTNDAPALAQADVGLAMNSGTTSAKEAANMVDLDSDPTKILEVVEIGKQ
                     LLITRGALTTFSIANDVAKYFAIIPAIFTLAIPQMEILNVMKLSTSFSAILSALIFNA
                     IIIPCLIPLAMKGVKYRPMKSQAMLMRNMLIFGLGGVIVPFLGIKLIDLLITPLVMVL
                     NLG"
     gene            19789..20415
                     /locus_tag="PC465_002072"
     CDS             19789..20415
                     /locus_tag="PC465_002072"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HDF2649366.1"
                     /translation="MKTLKPALLVSIVLLVVCGLVYPLVLTGVSQVAFKDKANGSMIE
                     VNGVKVGSELIGQSFTDARFFKGRVSSVNYNTYTKEDLVPDKDGNTSYGGVSSGSFNY
                     GATNPELHDRVQKDIEKFLKDNPTVKREDIPTDLLTASGSGLDPNISPASAKIQIPAI
                     AKASGISESKLQKIVDDNTSKKLFGVLGEDRVNVLKVNVEVAKILGLI"
     gene            20652..21560
                     /gene="cysK"
                     /locus_tag="PC465_002073"
     CDS             20652..21560
                     /gene="cysK"
                     /locus_tag="PC465_002073"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HDF2649367.1"
                     /translation="MLYNNALELIGNTPVVRLNNLGCTNGCSNIYVKLEKVNPAGSIK
                     DRAVYEMLEGLEQRGELKKGDVLVEATSGNTGIALSMIGKLKGYEVVIVMPETMSVER
                     RDLMKAYGANLVLTDGKAGMAGSIEKANELLKENPNYKSLKQFENKDNPNAHYKTTAV
                     EIMNDVKDLDIFVCGVGTGGTLIGTARYLKEQNPNIRVIALEPKKSPAISENKTGPHK
                     IQGIGANFVPENYDSSVVDEVILVDDEDAFDTVKLLAAKEGILVGISSGANIFGAIEM
                     AKKYPDKKIVTVAPDGVDKYMSMGIF"
     gene            21587..22177
                     /gene="cysE"
                     /locus_tag="PC465_002074"
     CDS             21587..22177
                     /gene="cysE"
                     /locus_tag="PC465_002074"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HDF2649368.1"
                     /translation="MFKKINKDIEYIMKNDPAARSKIEVFLLYPSVHAMIMHRMAHAL
                     YKKKKLFTARLISQISRFMTGIEIHPGAKMGEGILIDHGMGVVIGETAEVGNRVTIYQ
                     GATLGATGKDTGKRHPTVGDDVLIGAGTKILGPLNIGSNSKIGANSVVVKDVPNGATV
                     VGIPAKIVKIRNLEPVKKNKKEVSYEYDELDNVYYI"
     gene            22337..22525
                     /locus_tag="PC465_002075"
     CDS             22337..22525
                     /locus_tag="PC465_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HDF2649369.1"
                     /translation="MKANVNQDTCIGCGLCPSICPEVFDMKDDGKSHVIVDEVPSDAE
                     ESAAEARESCPVDAIDVH"
     gene            complement(22579..23448)
                     /locus_tag="PC465_002076"
     CDS             complement(22579..23448)
                     /locus_tag="PC465_002076"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HDF2649370.1"
                     /translation="MKLNRNDSCWCGSTKKYKKCHMDMDNKIDSFAKLGHIVPTHDII
                     KNESQIEEIKKSAVINTKILDYISDKIEIGMSTEDINKLVHDFTLQNGAIPAPLDYNG
                     FPKSVCTSVNNEVCHGIPSKDIILKDGDIINVDVSTIFNGYYSDASRMFMIGNVNENA
                     KKLVQVTKECVQKGLEVAKPWGFLGDIGDAINSYAKKNGYSVVREIGGHGVGLSFHED
                     PFVSYVSKKGTEMLLVPGMIFTIEPMVNEGTHEIFVDEENNWTIYTKDGKLSAQWECM
                     VLVTETGVEILTE"
     gene            complement(23645..24889)
                     /locus_tag="PC465_002077"
     CDS             complement(23645..24889)
                     /locus_tag="PC465_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649371.1"
                     /translation="MENNLNTAKRNNTELLQNDSLKVNLQIGVDFTLLSKSLKAFYKK
                     EKDFYCIALAPCNVSSEKANRKISIYDMIKEINILIESITDKNELLSEELFTNNLSEF
                     YDESLGEIYIDLKQAYLYIKKNTDSLNIEDSIEYVFDVDISNDIKAKENPLINFNSLS
                     LVVWSGETKHILQQMNILDLEDIHSYSIENNTNITIYENNTLQYKFDEESENIKDSSI
                     DIIEQMLILPDDLNYDKDEVENMKSRLAKINIKYLQTLKEKDIKIKLINSNLTDEPEF
                     SDLKYQLPPCWVRSGKTWKDVPGIYRNNSIVAKIGYSNPSYANVHSSKNLELHETAHA
                     IDKNVLNKKSNSEEFMEVFAQERYKLYDPKQVAHAYISKFIEEFFAESFVHYYLDEDS
                     KNTLKENCPLTYDFLEKLELNY"
     gene            25180..25491
                     /locus_tag="PC465_002078"
     CDS             25180..25491
                     /locus_tag="PC465_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDF2649372.1"
                     /translation="MYFTYIIRCKDDSLYTGYTSNIVRRMNEHKLGINSKYTRAKGFE
                     KLEVYFVTNTKSNAMKLEYYIKKLTRNKKLSIIKNPSILINLIDNKEDYIIGKKIEQL
                     T"
     regulatory      25584..25676
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            25776..26570
                     /gene="thiD"
                     /locus_tag="PC465_002079"
     CDS             25776..26570
                     /gene="thiD"
                     /locus_tag="PC465_002079"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HDF2649373.1"
                     /translation="MSNYKIPTLTIAGSDSSGGAGIQADLKTFSAIGTYGMSVITAIT
                     AQNTKGVFAVEDLNKKIIKKQIEAVFEDIPPRAVKIGMVSSPEIILEIVENLKKYNPK
                     YLVVDPVMISKSGYYLLKPEAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMK
                     RVGEEILQLGPKFVLMKGGHLDGEAVDILVGKNIFKVYKSERIDKKNTHGTGCTLSSA
                     ITSYLALGYEITEAVNLSKIYITEAIKRSFDIGHGVGPVHHFYKFE"
     gene            26594..27382
                     /gene="thiM"
                     /locus_tag="PC465_002080"
     CDS             26594..27382
                     /gene="thiM"
                     /locus_tag="PC465_002080"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HDF2649374.1"
                     /translation="MYNLIKDVKKLNPLVIHYTNNVTINDCANVTLAVGASPLMSFSY
                     EEVEEMVSVANSVVINIGTMNSNMLDLFLLAGKAANKYNKPVVLDPVGVFASKARAEL
                     TSRLLNEVKFSVVKGNVSEIKFIGGFNVKGKGVDSFDEEEDSTEIIRKIAEKLECVVV
                     ATGKIDIITNGKGTYKINNGTDKLKGITGTGCMTASLIASFMAVTENILEAATMGVLT
                     MSLSGELANLNNPPIGTFKENLMNAIYQMDIDTLSKNSNIEFLN"
     gene            27405..28037
                     /gene="thiE"
                     /locus_tag="PC465_002081"
     CDS             27405..28037
                     /gene="thiE"
                     /locus_tag="PC465_002081"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HDF2649375.1"
                     /translation="MIDKESLKKCLKLYLVTDSEMLKGRDFYKCLEDAISSGITTVQL
                     REKNASGREFLRKAMKLREITKRYGVKFIINDRVDIALICDADGVHVGQSDIDVREVR
                     KLIGNNKILGVSARTLEEAICAKNDGADYLGVGSIFTTSTKLDAKSASFETVKEIKEK
                     VDMPFVLIGGINLDNIDKLKCLESDGYAIISAILKAEDISKEVEKWTLKI"
     gene            28176..28478
                     /locus_tag="PC465_002082"
     CDS             28176..28478
                     /locus_tag="PC465_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2649376.1"
                     /translation="MIRILLVCVGGMSSTLLVNKMEKDAKKRNIDCKIWAVGEGDIKS
                     ELDNFDILLLGPQLRFMLDDVKSIVGDRAPVSIIDMVNYGTCNGHAVLNSVLEILK"
     gene            complement(28544..29293)
                     /locus_tag="PC465_002083"
     CDS             complement(28544..29293)
                     /locus_tag="PC465_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2649377.1"
                     /translation="MLNILWRSMKWRFKNPISFVVTILQPFLWLVLYSSIANQTMNNI
                     NINNYTAFILPGIIVLVVFSSCSSGGIINFIMKNSGSFYRVLIAPISRYSIVLGQLLE
                     AILVSFIEVTILCIVSIFFSVRIESGIGGILLMIVLIFMTAFFLSSLAYSISLLLPNE
                     IVYETIMTAIVLPIFFLSSALFPIESLSGGLKVAVMLNPFTHVINALRSLIFGETILI
                     GDILPFILLFLILCCSSFSLAMWRLKKEMVS"
     gene            complement(29287..30249)
                     /locus_tag="PC465_002084"
     CDS             complement(29287..30249)
                     /locus_tag="PC465_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2649378.1"
                     /translation="MLAIEIDNLVKEYKNGVKALNGLSFNVNAGEIFSLLGPNGAGKS
                     SLINILTTFYKPTSGNVKMFGKDLVDNSSWIRTQIACVAQQISIDEHLSLMENMVFQS
                     KMYKVEPQIAKQRIDSLIDKFDLSSYLKYPTSSYSGGVKRRLDIAMNMVSSPKILFLD
                     EPTVGMDVDSRKSMWDMLLKIRDEYGTTIFLTTHYLEEAEQLSDNICIMKNGKDLAQG
                     TPSSLRSYIRQNILRITFHNTEDIKKYKDSIKSTGLVKFMSVRENSIFISVNDSRTAF
                     TLINKWLLEHDIEFDAIEIVEPSLEDVFLALTSSKKSLKEEWEC"
     gene            complement(30253..30711)
                     /locus_tag="PC465_002085"
     CDS             complement(30253..30711)
                     /locus_tag="PC465_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDF2649379.1"
                     /translation="MNCKIEIKNIESVTVATMRYNGPMTEATKYFPNVFKAIKGKSNG
                     APFFCYYDVDQKTGVAEMELCVPTAETPNRMGITTKEFPKTKALFFTHTGSYSNLPKT
                     YEMIFKYIHENNIKIQTPWREVFIKGPGMLIKGNPDNYITEIIFPLKEEE"
     gene            31067..31423
                     /locus_tag="PC465_002086"
     CDS             31067..31423
                     /locus_tag="PC465_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2649380.1"
                     /translation="MNFELDNTTPIYLQIVKYIKRQIVTGELKPGETIPSRREMALNL
                     KVNLNTVQRAYKEMGDMNIINTFKNYQSSVTVDENILKNLKLELINESLSVFIEDMKA
                     INVSKEEVLKIIEDKY"
     gene            31495..32211
                     /locus_tag="PC465_002087"
     CDS             31495..32211
                     /locus_tag="PC465_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2649381.1"
                     /translation="MIEIKNVSKTYKRMQGLKIRKIEALKNVSFNIEKGKITALLGIN
                     GVGKSTMLKAIAGLINIDSGEIRIDGEKINEKVYNKLAFVPDVQSHFSNTTIKETFEF
                     MEIFYSKWNKEKSKEMMDIFKLDEDEIIDNLSKGNIARVKLILGFCQDPEYILLDEPF
                     TGIDLFKREEFIGVIAQYMEENQAIIITTHEIVEIESLVDEVVILDEGQIITSFNAEE
                     LREREGKSILDKMREVYKNE"
     gene            32204..33028
                     /locus_tag="PC465_002088"
     CDS             32204..33028
                     /locus_tag="PC465_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2649382.1"
                     /translation="MNKLLYLINVDLRRSNKFYIAYISFFSLITLSLNLFEINKFKNS
                     KFIMNLAIEDFGGIFYGLGILSNLGFIQSILFFGILGLFIYYIFMWKREFFSNNQSIY
                     TLMMLPQNKFKICISKSIALITMIYGFLISQTATLFICKYIFNFIFRNMPIINMNFAK
                     DLYYLNLKSIPIDFISFMAIYVFLLLIAISIVNCCILFIFSYINKFYVILITLLIIAG
                     LYFSTIYINIITLFRKYYNLIGFQFNNLVAGLLSFLIIMFILNGISYLLIKKKVSL"
     gene            33040..34239
                     /locus_tag="PC465_002089"
     CDS             33040..34239
                     /locus_tag="PC465_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649383.1"
                     /translation="MKLKSKISIFIIFLTLAIYFSIGLLNNEDNLKIKTIKGDSNELD
                     HININFGYALNGYINSYYTINGSNKTKKTELIKLQKDSKNTNNLIDVSSGSDLIAHVG
                     FEMNEESKDINFVIDEKKEDLEKGVFPSEGSDKEIEYEKLDMNNFTRTRYKVDKSTDD
                     YYAKILASKRYKKYLYVSVLYATSDSSENNKEYSSTIDIIKINPENKKIKTIKSINLS
                     NYFSEKYQNIENIGVSYASKYEDKMYILVNVLNTNIGDNSNSKFHLLEYNLEENKESI
                     MELKTDSKMALAKAKLEANKLYMVMSNDYDNSSITELNLLTYNILDKSLDEDKYVLDN
                     REKRGIRSIEIDSNKIVAYTSRLNSILSWDDKFMLYIINKNSKEIVYEGELQFNSSNS
                     MLEFEIK"
     gene            34248..35060
                     /locus_tag="PC465_002090"
     CDS             34248..35060
                     /locus_tag="PC465_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649384.1"
                     /translation="MKDLIRLFEFELKRNIKNYIFIIICCCSFVILNIVKNLNDYNYI
                     IENAVKSEQLTKIGNTIETVNVTGFSSFRNIMGSTESWFMFGIIACICYAFFIWYRDF
                     NGRSKSIYTLIMLPKNRINIYISKLLNILFLVYSYTVVLTISLFIASKLLPRHMLGNV
                     TNYGFVQETIYELKMLLPYSFEILFVEYIFLLIGFVSVVFTSILINKSIYKVSTLISF
                     LFLVIEILVFIISIEFIIPYEYSDVFTVLYSSINIFVCSLISNKLLKQKIDF"
     gene            35071..36339
                     /locus_tag="PC465_002091"
     CDS             35071..36339
                     /locus_tag="PC465_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649385.1"
                     /translation="MKAKNIGKYTICFIIVCFLMITMTLILSYFNKDKLSVKTLKGNV
                     KDIGRVSVVYTPDISKFSYEEVIISKNGVRNNTNPKSRIRNDYLNIDKKYSDFVNDKG
                     KEFIYKDDLNIGEAYTSVKSDLVQGMNALNDCIKVSNKNLKSGVEENFDINLNKSDFK
                     ENSWKTLFNKIYKGNLYMVISETNISGSKVNNICILKIDIKNKSYKLLNRFNLGLQNG
                     EQQNINEIKFSIGSKLYLEIVNNKSKNGYIEGHDSYSNFIIYDIEDNTFNISNKFMDN
                     LNKEKNANPKEIGLLSKTKLDYMVKNNKLNLIVTDMSNSITNLVYDINSNEIKLEDYE
                     ILDLKVDYNEASSGVRKVKLLDDKIYSISGIKNSISGELKGFKGVVDVVGTKPVKFQV
                     FDMKLKKNIYEAELINGDISLQEKLFFVAN"
     gene            36705..37886
                     /locus_tag="PC465_002092"
     CDS             36705..37886
                     /locus_tag="PC465_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2649386.1"
                     /translation="MNKKYIKAGNLIDGTGNSIMQNKGIIIDGDTIVEIEDIRDDLNG
                     YDVYDYLDKTVMPGIMNCHVHLTMEPVGNPKIYYDNVSDVELVVNTIKQLDAYLDSGV
                     TYIRSLGCPKYVDVQLKNLIDKGSIDGPGIVTSGPVICMTGGHGYYFGIESDGVDECR
                     KSARTVLKNGVDCVKIMATGGVTTDGVEPGSPQLTLEEMKAAVDEAIKAGKITATHAQ
                     GRTGIKNAVLAGITSIEHGVYLDDEIIDLMLERGTYLVPTVAAPYFILNAGKESGITE
                     ATLRKCEIVAIPHKESFLKAYKKGIKIAVGSDAGTSYNEHGKTYYEMKLMSDYGMDNM
                     DIIVAATKTASELLRIDKNYGTLEKGKKADVIVVNGNPVENIDVLADVLAVFKLGKKV
                     R"
     gene            complement(38028..38945)
                     /locus_tag="PC465_002093"
     CDS             complement(38028..38945)
                     /locus_tag="PC465_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649387.1"
                     /translation="MENNKCREDFRFTQEYEEDYPNTNERYYENYQVADRYYNYPNKY
                     KEPKIKQCCCKKSMREALELLRYDALRPFVNFNQFAFISDFFIVGANLVGIDLSAPPK
                     DNLSELDGTFERFSACNCDLIDIAGRVSYPIPVPLTLEGLINTIGTIPGVAELIALID
                     AVIPPTIDLGAILDAILAAIIDFILAASTPLANVDLASLCNLKAVAFDITPADYEDFI
                     ASLGYYLDKKHYKECNCNCDCDDCCCNKGILDNLYMSNINNQVTVVAGSLVLTGVEVL
                     GKKNDVIVLGNSNDSRIYFVCVDSIDYIA"
     gene            39198..39992
                     /locus_tag="PC465_002094"
     CDS             39198..39992
                     /locus_tag="PC465_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2649388.1"
                     /translation="MIEVDKLCKSFTRVVKDDKNKSSIRKLKKVKTKKEEFFAVNNVS
                     FKVMEGEIVGILGPNGAGKTTLLRMLGGILTPTSGSINISGYDYSIDRNSAKKEIGYL
                     SGNTKLYGRLSPRELLTTFASLYEMSKEDIEESIENIVKIMDMSEFIDNRIENLSTGQ
                     TQRTSIARCLIHSPKVYIFDEPTLGLDVLSSASIIDFMKNEKLRGKTVLYSTHYMEEA
                     ETLCDKIFMIHNGKIIASGTPQSLKEESGVNNLRDVFIELARKEDI"
     gene            39993..42053
                     /locus_tag="PC465_002095"
     CDS             39993..42053
                     /locus_tag="PC465_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2649389.1"
                     /translation="MRSKIVKYIFKKEMLDILRDKKTLFMMIVVPLLLYPLLMLLMIQ
                     VMNMSASSMNSKDINIAFNNKPNKVLVSMIEDDNLEKDTKNTSNDKGKIRVLDVDNYK
                     KSLEENKIDAYIKMEEKKSSINYQIYINSSQENSSNALKRIETVLDKYKRFTIEKTLS
                     EKGLDVQATLEPITYSTVDVAKTEEVAGYFLGQILPFILIIGVLLGSIYPAIDVMAGE
                     KERGTLETLFTLPISNLELVMGKYMAVSLSAIVTAILNILSMGLTMAFILVSGGISSQ
                     FGFGNFNYGDLVLPIITTLICICLFSMVVSAISMCVCSLAKSFKDAQNYITPLMLIIM
                     IPSYVSMIPNIVLDRVTAVIPVVNISLLIKSVLSFKSDLNLIALVLASNVAFVILAII
                     LLSKMFNSEEILFGNSKSFSFLEKRSNIKKGSIPTVSDGVILYAVGLILLIYVGSLVQ
                     IKFGMAGIIMTQFMIISLPLLFAYYIKADFKEVFSLTVPKLKHVFGSIVLWIGGYILI
                     MIITQLILFLFPQNMEVAESLNKALFIKDSVLLNLLAIALLPAICEEMFFRGFIFSSF
                     SKSKDKNKSIKLAIICSGVLFGIMHMDFIRIIPTSILGIIFAYSVYKSGSIFVSILLH
                     FLNNSVAVVLNHYTTGNITNLYKFVEVDFSNLNVLKFALILLISLILIMLGLRVLDRK
                     SLRN"
BASE COUNT        16428 a         4497 c         7249 g        14055 t
ORIGIN      
        1 tagtattatt ataaataaca ttgaaaggta gtggttagaa tatggatacc cataataaat
       61 atgtaaattt tataaaaaat atacctgtac cttttttata ttgtagaatt gtaaagagac
      121 aagaagatat agaatatcga gtagaatata taagtaaggg tatgggcaaa gtattacaat
      181 tagaagaagg tatttgtgat aaaaatatac tagatgtatt gcctgtattt aagtctaaaa
      241 aatatttcaa agagttgttc tcaaatgaag tggattgtat aaaaaggtac attccgacac
      301 ttaaaaactg gataaatata aaaaaacaga taatagggga ttcatacata attttgtatt
      361 ttggtaaaat tgtatttgat tatagacaga taatcgattc ctttgataaa aaggaaaaag
      421 tagcttatat taaagacgaa gaaggcatat atatagattg cagtgaaaat ttaataccaa
      481 tattaaataa caacattaaa acaacgaaag atatctttgg taaaaatgat atagaagtat
      541 ggggagagaa tacaggaaaa ttatttagag atgattatag agaaggagta tctagtaaaa
      601 aaagattttt acaaaatctt tttgaatatg aagaaacatt ttttatggtt gaaaaatatt
      661 ttttgtatga tgaagacgaa cttttaggta ctatagggat agtagacaat ataatatata
      721 gtggttacag taatagaaat tataactcaa aagatttaat gaagatgata gaacactcaa
      781 ttccagagaa tatgttttat aaagatgtgt atggaaatta tattggattt aattcaggtt
      841 ttttgaattt agcttgtatg aataaagaag aattattagg gaagaatagt tataaaatat
      901 cagaagaaga agctttaata gataagatat ttgaaagtga taagggtgta gttgaaaata
      961 aaaaagtagt tacatttgag ttaaatataa gtatgaatga tgaaaacaag tgcattgaga
     1021 ttacaaaaag gccgtttttt gatagctatg gaagtgttat tggaataatt ggaacagcaa
     1081 gggatataag tagaagaaaa agattagaag aggaaatgga taaaactagg atggaatttt
     1141 ttgcaaattt atcccatgaa cttagaacgc ctataaactt aatatcatct tcattacaag
     1201 tgatagaaaa aaaagaagca gatttaatag aatcaaatga tactttaaaa agaaatttag
     1261 gtataataaa acaaaatgga aatagaatac tgaggttagt aaataatgtt atagatttta
     1321 caaaaatgca atcaggatat ttagatttta aaccagaaga atctgatata attgcattta
     1381 tagaggagat atgtatgtct gtagctgatt ttgcaagcca aaataatata caacttacat
     1441 ttgatacaga aatagaagaa ttttcaatgt tatttgattc agaaaaattg gaaagaataa
     1501 tattaaattt actttctaat ggaattaagt acaataagaa agatggaaaa ataaatatat
     1561 ttttatatgt gaaagataat gtatttaata tgaaaatatc tgatagtggt ataggtatac
     1621 caaaagaaaa aatagataaa atatttaata ggtttgaaca gattgacaat gaactttctt
     1681 acagagttaa aggaagtggt attggacttt cattagtgaa atctttggtt gagttgcatg
     1741 agggaagtat atctttaaaa agtcaacttg gtattggaag tgaatttata gtttcattgc
     1801 ctgttagaag taaaaataat attgaaaaat ataatcataa aagagaaatc agcaatgaac
     1861 taagtaaaaa attagaaata gagttttcgg atttataagt ttaaatataa aaaataaaat
     1921 tttaaaaaag tattgacaat tgatttagaa gggtttaaaa taaattacaa cataataaat
     1981 aaaaaggcga tgaataggaa gagtaaatct aattcgatta ccagagagaa gagtccgttg
     2041 gctggaagac tttttaaatt agagggattg aaaactacct aggagctact ttctgaagtc
     2101 atctgcatta gtagatttta gtaagaatag tcgttagctg cgttaaagtg taaagtgagt
     2161 tttcatgaca tatgaaaact aaattaggtg gaaccgcggg aataatactc tcgtccttat
     2221 gttataagga tgagagtttt ttgttattta aaaatataaa cagtaatcat aataattata
     2281 gaaaatataa aagcaatgaa taggaagagt aaatttaatt cgactatcag agaggaaagt
     2341 tcacaggctg aaagactttc taagtttgag aaattgaaaa ctacctagga gctgtggtct
     2401 gaagttactt taaaaagttt tagtaagact aaccgttaac tgcgttaaag tgtaaagtgg
     2461 attttatcaa taaatgataa aatcaaattg ggtggaaccg cgagtataga ctcgtccctt
     2521 tatataggga tgagtctatt tttattgcaa taaaagattg aaaataaaaa aaaatcggaa
     2581 aattataaat ttaggaggaa aataaaatgg agaataaagt gaaaattgga gtactaggat
     2641 atggagttgt aggaagtgga cttatagata taatagataa taataaagaa aaaagaaata
     2701 tagaaatagt tggaatttta gttaataatt tggaaaaaca taaggataaa aaatattcta
     2761 atataataac taataatata gatgatatat ttaataaaga tatagatata cttgttgaag
     2821 tcatgggtgg tttagaacca tcattatctt atataaaaaa agcattaaac aataaaattc
     2881 atgttgttac agcaaataaa gatttgttag ctgaatgtgg agatgagctt gcaaaattag
     2941 caagtgaaaa taaagtaagt attaaatttg aagcttcagt tgcaggaggt ataccagtat
     3001 taaaaccaat aatagaatca ctagaaggaa ataatataga tagtataaat gcaattttaa
     3061 atggaactac taattttata ttatctaaaa tgtatgatga gaatctatct tatgatatgg
     3121 cattaagaca agcacaagaa ttaggttttg ctgaagcaaa tccagagtca gatgtattag
     3181 ggtatgatgc tgctagaaaa ctatcaatat tatcaactct agcttatgac aatagagtat
     3241 attggaaaga tgtgtattta gaaggaatta cagatataga tgaaaaagat attgaatatg
     3301 caaaaaaatt aaattgtaaa ataaaattga ttggtcaaag taagtatgaa aatgataaag
     3361 taagtgcttt tgttagacct gttttagtag aaaaagataa tatccttgct agaatagaca
     3421 atgagttcaa tgctgtcata gtgaatggag attcagtagg agaagtttct tttgtaggta
     3481 aaggagctgg aagtttagca acaggaagtg cggtttattc agatgttata gatataatag
     3541 ataatagagt ttcaagtata gattctttta ctaaagataa aatacaagtt aataaaatag
     3601 ttagagaaaa gtgtggagca cttcttagat ttaaaaaatg taataaagat gaaattctaa
     3661 atatagttga gaattgttta gtaaaattcg atattttaaa tgatgatgat gaacttgcta
     3721 ttatggttta tgctgattct gaatatgaaa taaacaacag tttatgtcta ataaaagata
     3781 aaggatactg cgaaaaaatg aataaaatgt tgaaaataag ttaaaaaaga aaaaatataa
     3841 gtttatatgt aacatatttt gacgatttta atactatata gtatgagatg aaacaaaaca
     3901 tctcataaaa aaattaaaat taaagggaga gatatgttat atggaaaata aaaaatgtta
     3961 ttcagaagat tggtatgaaa gaggagaatc tacagctaaa tggttccaaa atgatagaga
     4021 agaatatgaa agagaagcat atgatgaaga tagagaaaga agaggttcaa actgtggatg
     4081 ttcagattca ggagaaaata gacctagaaa ctgtgaaaga tttagaagag aagctgagat
     4141 aagagaaaga gaagcaagag aagcattctg tgaatcttca gagaaaaaga aagaggcatt
     4201 agcatatgaa tgtgaagcta gaaaattatg ggaagaagca gaaaaatact gggatgaata
     4261 ttcaaaatac aactataaag gaatcgaata tttagcagaa gctgctagat tatttgatga
     4321 aggtatggaa tgtgaagcta gaagaaatgg aaataatgga ggaaacaata ataattgttg
     4381 ccataaatgc cataaatgta attgtaactg ctgtagaaaa taaaaaaatt aattgacaaa
     4441 tcaatagtta aaatatatca tattatgtat aataaagaga aaattcagaa aaaaataatg
     4501 attagaagaa atataagtat atttattaga caaatagtgc tcagttagtg aggtgagtac
     4561 aatatgatta aactcccatc ctctagcttt tgatagaggg tgggagtttt tatttattta
     4621 tatatcttaa atgaggataa tattgtaaaa taaatgagta tgagattgta aaattaggag
     4681 gtaaaaaatg aaaagtatta aaacatcaag tatgaaagaa aaggtagatg aaaagatatt
     4741 aagagagcaa gtaagttcta taatagaaga tataagaaat aataaggatg ttgcacttaa
     4801 aaaatataat gagaagtttg atagaaatac aagagatgaa tttagaatta ctaaggaaga
     4861 aataaaggaa gcttataagc atgtagatga cgaatttata aataacttaa agattgctgc
     4921 caaaaatata agagaatttg ctaaagctca aaaactaagt tttgaaaacc cttttgaaaa
     4981 agaaatttat ccaggtgtaa tcttaggtca aactaatatt ccaatagagt catgtcttgc
     5041 atatgttcca ggaggtcagt atccattgtt ttcaacagct cttatgctta taatacctgc
     5101 aaaagtagca ggagtaaaaa gaatagtggc atgttcacca actatgaaaa atactgaaaa
     5161 gataaatcct aagacattgg tagctatgga tatagcaggt gctgatgaaa tatatgcaac
     5221 tggaggagtt caagctatag cagcatttac atatggaaca gaaaagatta atccagttga
     5281 cataattgta ggaccaggaa ataagtttgt aactgaagct aaaagacaat gttatggaca
     5341 agtagggatt gattttgtcg ctgggccaag tgaagttctt ataatagcgg atgaaacttc
     5401 aaatccagtt tatattgcag ctgatttatt agcacaatgt gagcatgatt taaatgcaag
     5461 aggaatatta ttgacaaata gcttggaagt agcacaaaaa gttgaaaaaa atatagaaag
     5521 tatgctaaaa gatttgccaa caaaggacat agcatatagt tcatgggaaa ataatggaga
     5581 gataatattg gttgatgata tggaagaagc cattaaaata agtaattttt atgcaccaga
     5641 acatttagaa gttgcagtaa atgagtataa tgatatttgt gatagattaa ctaactatgg
     5701 ttctttattt attggaaatc tttctgctga ggtatttggc gactatgttt caggtaccaa
     5761 tcatacatta ccaacactta aagcatcaag atatactggt ggtgtttggg ttggaacttt
     5821 tatcaaaact tgtacaaagc agatatttaa tgaaaaagct atacaatcat tagcacctgt
     5881 agctgaaaag ctggcaaaag aagagggatt atatgcacat gcaaaggctg ctgaggttag
     5941 gtttaaaaag tagtaaaaaa ttttattttg gcagtcgaga tttagtgtta gactgagata
     6001 aggaaaacgc tgagaacccg aataaatact atattttgtg ggcctcggcg tttcttttat
     6061 atctgtatat aataggataa tactacctgt gtgtttaaat actaacttaa tatttctttt
     6121 ctaaataatg tttatgaaat agttaatatt tttagttaat agttgaaaaa aacttttgct
     6181 aactgtgcaa attcatctgc atttgtcaat atagcagggt gtcctccctg actaaaaatg
     6241 tgaatacttg cttttgaaat aaaagttgcc atttgtttgt actcttcttc aagattatga
     6301 cgacacattt cgtcttcctt acttcctgta aataaaattg gcatttctaa tttacacaat
     6361 tctttatgaa acaaagggcg tttctcgttt gcacattgca atagagcttt tgtatcaaga
     6421 ttaacaacat tctcccaatc ttttccatga caccattcat agaattttcg tgcttgaata
     6481 tcttgctttg atttttccct tccagtgatt agattatcta tgaagttatc attaagagta
     6541 cgtccatcaa agctatctgc tataattgct tcaactaaat cgggacgttc taatccagta
     6601 ttaacagctg cccatgctcc tccacttgtt ccaattaagc caactttacc acaattcaaa
     6661 tgttcaatca gtgctattgt ctgtaaggct tcatcatgcc atatgtcagg agaaaattga
     6721 gaaactctat ccgactgtcc attacctaaa aaatcaatta agatacatct aaaattttct
     6781 gcatataatg gcacaagtgc tttaaacata ttagaagaac cagtattacc atgcaggaaa
     6841 attatcggtt taccttgtcc atattcttta taaaaacaag aattaccttg atactgaaaa
     6901 tatgacatat attttcctcc tttttatttg ataagttaat tataacaata taggtatgaa
     6961 tgaaaaacct catgttcttt cttagaataa aaatgtgcca cgcataaaac gtgacacatt
     7021 tctaattata aattttgctg tttaagtatt ctttgtatgc ttttctctgt caaaaagtat
     7081 ttctctgata actgcttgat actcattcca ttttggaaat ttatacagat ttgagaatta
     7141 cgagaagcta agacttgttt ggtgtttgtg ttttcacccc aatgcttttt gtgctcttgc
     7201 tttttgggaa tataaatcac tttaccatct atatattctt gcacttgctc aatcagttct
     7261 ttaggcagta agtcaatcga attttgatag ctcattttgc acctcctaaa taattattct
     7321 ttaggattag caaaggctac tgccactcac aattaaaaat aaaatttttt attatgtaca
     7381 atagcctttg ctatgcacaa gttccaattc ccataaacta aatactcctt tctggtttga
     7441 aaaattcatc tgaacattga tttcgctttt aagatagagt tcaatgacaa atttacattt
     7501 ttattatata tattcagata gataattgca actgtctttg tatgaggata ttttattata
     7561 gtcaatacta taatatgtat ttatatcatc aaactaatat gaacagttga aaggaatatg
     7621 aacaataaaa cttagtcagg aagaataatt atgaagcaga taatagagaa atttgatttt
     7681 aaagttttat tgaaaattta ttgacaaatt taacttgtaa atattatact aaacttaata
     7741 aataaagttt ataaagtaag gtgttgtcta tgaaaaatat agttggaaaa ccgcaaacga
     7801 taaaaaaagt aaatgaagat ttaataaaaa acattataaa aaatgaaggt cctataacaa
     7861 aaccagaaat ttcaagcatt actgaattga gtttagctac agttaataag attgtagagc
     7921 aattagcttt gaaaaatgaa gttaaagtaa gtggactaag tgaatctact ggaggaagaa
     7981 gagctcaatt atttgaaata aatgcaaact tagaacacat aatagcttta tattattata
     8041 gaaattgttg tataggggta gttgccaatt tattaggtga aataatttat caagaagaat
     8101 ttaatataag aatggatacg tatgaaaacg ttaaccaaga tacttttttt gttatagata
     8161 ctctaataaa aagggaaaaa ggaaacaata taagggctat tggaattggt gtcccaggag
     8221 ttgtaaaaaa aggtgtagtt aaaaatatac caactataaa aagttgggaa ggtataaatt
     8281 tagaaaattt aataaagagt aaatacaata ctaaagtgtt tatagaaaat gatacaaata
     8341 ttactactat tgggatttat caaaaacagt ataaagacaa atataaaaat atggctctta
     8401 tgtatttaga agatggtatt ggttcaggta tagttataaa tggtgaattg tatttaggtt
     8461 ctacaaattt tgctggagaa ttaagttatc taaatataga atttggtaag tataactcta
     8521 acaacttaaa tcttgaagat tatattatga gtttaagaaa aagatattta gaaagtaaag
     8581 ataataaatt taagaaagaa attttatcta taatatcaaa ctttataagg actcttgtat
     8641 gtgtcctaaa tccacaagct atgattatac agtgtagtat attaaccaag agtgacatgg
     8701 agtttataga aaaagatgta agcaataatg ttggagaaga aaattttcct aaattaataa
     8761 aagtagagtc attgagagaa ggaagtataa atggagtaat tagtatgtgt ttaaaagaaa
     8821 ctgactatca atattcctta tctaataaaa aaggaggata ttaatgtgaa atatttggtt
     8881 tcaatagatg gagggggaac aaaaactaaa ttttgtgtaa gtgacttaga tggaaacata
     8941 cttaaagaac ataccactgg ttcaactaat tataagtcag ttggaattaa aaaaacatat
     9001 gaaaatatta ataatggatt taaaaaaata ttaaaagatt tatatatcga ttatgacgat
     9061 attgagtaca ctgtatttgg tatatctggt tgtgattctc ctaatgatta taagattata
     9121 atggatgaaa tattaaaaat tgggattaac aaagaaaaaa tatatctggc aaatgatgca
     9181 gttttagctt tttatgcaca agctgattcc cctggtttag taattgtggc tgggacaggt
     9241 tcaattatac tgggaattaa agaagatgga gaaatatata gagttggtgg atgggggtat
     9301 aattttagtg atttgggttc tggatatgat atagggagaa aattattaaa gaaagtattg
     9361 ctttattgtg atgaatgtca tgagtatagt gatttattta gttgtgtctt ggatttcttt
     9421 ggagcaaata gttttgaaca acttgcatat atgattactg atataaatga taatgttgaa
     9481 atagcaaact tagcttcatt agtgattgat tgtgccgaac aaggtgataa attggctatt
     9541 gaaatattaa gagaatcatc aactgaacta tctaaattag ctcaagtaat attgagaaaa
     9601 atatctaatc caatgaaaat ggataaaagc gaaataaata tagttttgtc tggtggtaca
     9661 ttaaataaaa ctgtatatgc tcaaatgtta atgaataatt taaaaacaga aaatacagat
     9721 aaaaatttaa aatttatatc tcaagaaaat cagccagtat atggggggat aagacttgct
     9781 atggcattag ctaataggag ggccaagcat ggatagaaaa aaggtaatag tacaaatttt
     9841 tactggaggt tttaaggcta aagaaataaa gtttaatgat ataaaatgta aactactaga
     9901 attattggac tgtattgata tagaaaaggt tatcatggga tggagtgtag atgaagaatt
     9961 atatgtagaa actaaaaaac tattaaataa atataatgtt gaactatatc tttggttgcc
    10021 atgtttttct gaaataggat tacttgaaaa aagtaattta ctaattgatt atatggggaa
    10081 ggaagtcaag ggctatgctt tacaagagga tgaaaatttt gagttttatt gcccaaataa
    10141 taaggaaaat ataaaaaata taaagaaaat atatagtact tattttagtg atattaaatt
    10201 tgatggaatt tttttagata aaataaggta tggttctttt tcgaataaac taaatggtgt
    10261 ttttaattgt ttttgtaaag attgtttaaa tatatatgaa aaaaataata ttgataaaga
    10321 gtcgttaatg agagaaatga ataatgtgtc taagggagtt atagataatg aagatactcc
    10381 atttggtata acagaataca ttaatggaaa atacaaattt aaaaataaaa tatgggaaga
    10441 tttttttgaa acaaaaaatc aaaatatata caaggcatta ttagagataa gtaattattt
    10501 taaaagtaag ggattgaaaa taggtataga tactttttct ccttttattt cttactttac
    10561 aggtcaagat ttagaaaaat tacaagaagt agcagatttt ataaaaccaa tgatgtatag
    10621 aattacaaaa gctccagctg gtttaccatt tgaatttgaa aggtttattg atgaatccat
    10681 acataagaat aaagagattg gaaaaagaaa tttcttagat attttaggaa ttaaggagta
    10741 tgaaggaaat gtatacccta tagaatttgt actagaggaa atcgatttta tgacaagaaa
    10801 tcttaataaa gatatatatg taggagttga aataaataaa aaggaaatta tagctcctgt
    10861 tacacctaag tacataagtg aaaatatttc aaatataaat aagacaacag taaaaggata
    10921 tgttttatct tgggatttgt tatcagcacc aaaagaaaat attgatgaaa ttataaaatg
    10981 gtttcggaat tagtgaggtg atatagtgag taagatattg gaaatgcaac aaatatataa
    11041 aagttttgga aaggtagatg ttttaaaagg gataaatttt gagttagaaa agggagaagt
    11101 aagagctctt ttgggagcta atggagcagg aaaatctaca cttattaaaa ttttaggagg
    11161 agttcattcc caaactaaag gtaaagtaat tttgactggt aatgaaataa tgtttaaaaa
    11221 tccacatcat tctaaagaaa atggtattag tataatttat caagaattaa gcttgatacc
    11281 aacgcttaca gtacttgaaa atatttttct tggtagagaa attttaaaag gaagtgtgtt
    11341 tttaaacaag aaagacatgc ttgaggaata tatgaaaatt tgtgaggatt ttgattttaa
    11401 tatagaccca catatagtag tttctaattt aagtgtagca aaccaacaaa tggttgagat
    11461 aatgaaagct gtttcatgta attctgaaat tatcataatg gatgaaccta caacatcact
    11521 tactaataat gaaaaagatg ggctatttaa aataataagt agactaaagt ctaaaggtaa
    11581 aacaatagtc tatatttctc acatattaga ggaagttttt aaagtatgtg atagtacaag
    11641 tataatgaaa aatggaatta tgattggaac ttatgatgta gaggatttaa ctaaattaaa
    11701 gataactcaa cttatgacag gaaatgataa tcacaaactt attgagaaga aggattatac
    11761 atttgcaaaa tatgaagagc caccagtact agaagtaaag aatataagct ggtctaacaa
    11821 aataaaaaat gtttcattta aagtttatag aggcgaagtt gtaggtcttg caggtcttgt
    11881 aggttcaaga agaactgaaa ttataaattt gatatttggt atagataata aagatagtgg
    11941 agacattttt atcaatggta aaaaagtaga cataacttct cctaaggttg ctataaaaaa
    12001 caaaatagga ttgattcctg aagatagaaa aaatctagga ttaattttag aacaagctat
    12061 atacacaaac tcatcatcag tacaaattga taaattcaag aaattcttgt ttatagatag
    12121 aaataaagaa attgagtttt ctaaaaaagg tgttaaggaa ttaggaataa aagttagtga
    12181 tgtaaagcaa gaagtaaaag agcttagtgg tggaaatcaa caaaaagtag tagtttctaa
    12241 gtggttagag aaagatttag atttaataat atatgatgag ccaacaaagg gaatagatat
    12301 tgctgcaaaa gaagatattt tcaatacaat caaagaattt tcaagtaaag gaataggagt
    12361 aatatttata tcttctgatt tagaagaagt aataagagta agtgatagaa ttttagtaac
    12421 tagagaaggt tctattgtag atgatttaaa aaatgagaat atacaggttc aagatataat
    12481 gaacagtata tttaatgtat aaaaaatgaa aatggaggac tgagatgaag aaagcttttg
    12541 agaagttaaa tttaagagat tatggagtat tattaggttt tttagcttta tgtatagcta
    12601 taagtattgc aactccatca tttttaggta aacaaaatat acttaatctt ttacgacaat
    12661 cttctataat tggaataatt tcagcaggta tgacttttgt tataatatct ggaaactttg
    12721 atatatcagt tggagcagta gcagctcttg caggtgctat aacaatgaaa tttgcgactg
    12781 gtggaactaa tttgtttgca tccatgttct taggtgtagc gatttgtgca gtaataggat
    12841 taatcaatgg tatagtagtt gcaaagataa atgtaccatc attaatagcc actatggcta
    12901 tggtcactat tgtaagagga ttgctgttga tgcttacagg aggatatcca attactgaaa
    12961 atataccaat acttgattac attggaaatg gatatttgtt taatatacca ataccagtag
    13021 taattttctt tatagtggtg ttagtttcgt ttattgtact taataaaact aagtttggta
    13081 gatatgttta ttctgtagga gggaatcaag aagcaagtaa acttaatggt ataaatgtag
    13141 attctcacaa agtgaaagtg tttattatta atgctgtact tgcaggaata gctggaatcg
    13201 tactaacagg aagacttggg actgcaactg cgattgcagg tgaaggatat gatatggatg
    13261 caattgcatc tgtagtaata ggaggtacat cagtggcagg aggttctggt tctgtactta
    13321 aaactgttat aggagtatta cttatgagtg ttataaacaa cagttttaat cttcttggaa
    13381 tagatgtata tttccagtac atatttaaag gattaataat tttagcagca gttggatttg
    13441 attcttatag caagaaaaaa cttgcttcaa gataaaaaat aagggggatt tttttatgaa
    13501 aaaattaatg aaacatttag cattgttgct atcacttgtt atgatatttg gtttagttgg
    13561 ttgttcaaat ggtggtgaca aagaaaaaaa tggagaaaag aaaatagcag tattactacc
    13621 gggttcaaca ggttactttg tagcaactaa acaaggtata gatgcaaaat ctaaagaatt
    13681 aggtgtaagc gtggaatatg cagatgctca atgggatgct agtaaacaat tatcacaagc
    13741 tgaagatttt atggctaaag gggtagacat gattgcatta tgtggagttg attctgctgt
    13801 aagtgagaga atagctaaag ctgctaatga ttcagacgtt cctatagtag catttacaaa
    13861 ttctatagga agtaacccaa ctggagaatt taaaggttta gttacatata taggacaaaa
    13921 tgaggaagaa acaggagcat taactggaaa aattgctaaa aacttattag gagaaactgg
    13981 tgggaaagct gtattaatag aaggagtacc aggaactact ccacaagtat taagaaaaaa
    14041 aggtcttgaa aaagaattaa aagatagtaa tatagaaata gtttataatc aaacttcaaa
    14101 ttgggagaaa gagcaagctt taaaagtaac agaagattta attcaaaaga aaactgattt
    14161 taatgttata atatgtcaag atgataattc tgctacaggt gcaggtcaag ctttaaaaga
    14221 tgctggtctt aaggataaag ttaaagtcat aggtttgggt ggaagtaaag atggattaaa
    14281 agctataact gatgggttaa tagatggtac aacttatatg tctgctgtag aagaaggtgg
    14341 attagtcata gaaaaggcat ctaaattcct taaaggtgaa aaaatagaac ctgttacaca
    14401 aattaaacaa gttgaagtta acaaagataa tatttcagag ttcaagggtg aatggtaaat
    14461 tgtcatagat aataaataag atttttagag ttactttaga aactatataa agtaactctt
    14521 tttttaattt aatttagtga taaattattg aatagtattt ctaaacaaat aaaaaattaa
    14581 tataaacaaa gacttaatta tactaaatta taagtaaaac taatataaac ttatggaaaa
    14641 aaggaaaacg tctaaagtat tggaattact atagtgtagg tgtggtatta aaaaaacata
    14701 aaaaaacata aaaaaattgt tgaaaaaaat atagaaattt tgtataatta aagatttgaa
    14761 aagtgcggta tacaaagcca attcttttgt atataatata tataaattca gaaaaaggaa
    14821 gggatatgta tggccaggcg gttattttta gaaaggattg gacttatatt tttaggttca
    14881 gcaatattag catttggagt ttataatttt tattatttaa acaacataac agaaggtgga
    14941 gtgttaggta ttttactact gttaaaaaat ttattcaata tacaaccagc aatagcaaat
    15001 gttgtaatag atggtttact acttttagta ggatataaat ttttcggtaa aaaattcctt
    15061 atatattcaa tagtagcttc tataactttt tcagtgttat atgacttatt tgaagctata
    15121 ggacctctag taccacaatc acaaaatatg cttttatcaa ctattttggc aggtgtaact
    15181 gttggaactg gtgtaggtat agtagtaaaa gcaggttgtg catcaggagg agacgatgct
    15241 ttagcattag taatttctaa gactacatct ttgaacatag ggcaagttta tttagcaaca
    15301 gatgttattg tattgttgtt atcattattt tatctatcag cgtttgatat cttttattct
    15361 ttgattgctg ttacaattag tggcaaggta attgatttta tttattatca tggtaaaagt
    15421 ttggatatgg atataagtaa tgatatagtt ccagaatgtt aatataaatt aaataacttt
    15481 agattttatt aggggtggca gatttgccac cttttttgtg tctaaatctt tatagaaagt
    15541 ataatcccat ctaggttttt gtaaatctca aatatagaat tatgttggaa tgactgggaa
    15601 tacgattgct agatgtgcat tttaaaaacc aaattttata tttatgaaat actaatcatt
    15661 aatggatgtt tcttaatcct atctttatac ctaaaatgat aagataaatg aagtagcaat
    15721 acaaaactaa aatttgtaaa agagattaaa ttaaatggag gagctaaaat gttggatata
    15781 gttatgatag cattgttatt cataggattt gtttccatga agttacttgc tgattggtgt
    15841 gggaaacaaa ctgaaaaaaa ataatgtaat gtatggaggg attacctatg tggtttctgg
    15901 cagttgtaat tataatgtta ataatatatt tggtatatgc gcttattaat cctgaaaaat
    15961 tttaaacagt ataaggctaa taagtaagtt gaattggggg gaacaatttt tatggtgcag
    16021 atagtaatag tgttagcgat ttttatgatt ttagtaatac ctatgggcaa gtatttatat
    16081 catatagcta ctaatcaaaa aacatttgga gatagactat ttgataaagt ggacaatttt
    16141 atatataagg tatgtagtat agataagaaa aaagaaatga actggaaaca gtatgcatta
    16201 gctttattat ttacaaatgc agttatggta tttataggat atatcatact tagaactcaa
    16261 agtatgcata tttttaatcc aagtggaatt aaaagtatgg aacaaggact atcatttaat
    16321 acaataataa gttttatgac aaatacaaat cttcaacatt attcaggtga atcaggactt
    16381 tcatacttta gtcagatgac agtgataata tatatgatgt ttacatcagc tgcaacagga
    16441 tatgcggctg ctatggcatt tgtaagaggt ctagtcggta aaaagaaaac attgggaaat
    16501 ttttatgtag atttaattag gataacaaca agagtacttt taccaggagc tttaattatt
    16561 gggcttatat tagttacaca aggagtacca caaacttttg ctgggacaga aacagtgact
    16621 actatagaag gaaagcttca agatatagct agaggtcctg tggcagctct tgaatcaata
    16681 aaacatttag gaacaaatgg tggtggattc tttggttcaa attcatcaca cccatttgaa
    16741 aatccaacaa taatatcaaa tatagtagaa atattatcta tgatgatatt accaggagct
    16801 tgtgttgttg catttggtca catgataaag aataaaaaac aaggttgggt tgtgtttggc
    16861 gcaatgtcaa tcatattttt aataggtcta gtagtgtgct ttaaagcaga aagtgcagga
    16921 aaccctattt tatcacaatt agggcttaat caaagtatgg gaagtatgga aggtaaggaa
    16981 gttagatttg gtatagcaca atcatcatta ttcacaacag tgactacttc ctttacgaca
    17041 ggtacagtta ataatatgca tgatacactg actcctttag gaggattagt accactttta
    17101 aatatgatgc taaatgtagt atttggtggt aaaggcgtag gtctgatgaa tatgttgatg
    17161 tacgctataa tagcagtatt cttatgtgga ttaatggtag gaagaacacc agagttttta
    17221 actaagaaaa tcgaaggaaa agaaatgaag cttattgctt tacttattat attacatcca
    17281 cttttaatac taatgttctc tggtctttca gtagcaatac cagcaggact tgaaggaatt
    17341 tcaaatcctg gattccatgg attatcacag gtattgtatg agtttgcatc ttcagcagct
    17401 aataatggtt caggatttga aggtttagga gataacacta tgttttggaa tataacaaca
    17461 ggtatagtta tgttctttgg aagatatgtg tctattatag tactactagc aatatcaagt
    17521 ttgttagcat ctaaaaaagc tgtaaatgaa agtataggaa cacttagaac ggataatttt
    17581 acatttacaa tagttctagt acttgttgtt ttaattgttg gtgctttaac atttttccca
    17641 gccttagcgc ttggacctat ttcggagcat ctagtgttgt ggcactaaaa aattgggagg
    17701 gagtaaagtt ttatggaaac taaaaaaaca aagtttatta caaaagatat tttcaaaact
    17761 tccattatag aagcttttaa aaaattaaat cctaaatata tgatgaaaaa tccagttatg
    17821 tttgttgtag aaattggatt tatagtaaca ttgatactta caatagtacc tagtttgttt
    17881 ggtgatgaag gcaataactt aagagcttat aatgggattg taacaataat cttatttata
    17941 acagtccttt ttgcaaattt tgctgaagct gtagctgagg gaagaggtaa agctcaagca
    18001 gatacactta agaaaactag aaaagataca gtagcaaggg ttatagatac gttaggaaat
    18061 gaaaaaatga taagtgcaag tgagctaaaa cttggtgata ttgttttagt aaatgctgga
    18121 gaagttattc caaatgatgg agaagttata gagggcatag cttctgtaga tgagtcagca
    18181 ataactggag aatctgcacc tgtcatgaga gaatcaggtg gagatttcgc atctgttaca
    18241 ggtggtacta cagttgtaag tgactggtta aagataagaa taacaacaaa accaggagaa
    18301 tcgttcttag ataaaatgat agctcttgta gaaggtgctt caagacaaaa aacgccaaat
    18361 gagattgctt taaatacttt gttagtaggg ttaacactta tatttatggt tgttttaata
    18421 tctctttatc caatggcaaa ctatgcaggt gtaaagattc caatttctac tatgatagct
    18481 cttttggtat gtttaatacc aactactata ggtggattgt tgtcagctat tggtattgca
    18541 ggtatggata gagtaactag atttaatgta attgcaatgt caggaaaagc agtagaagct
    18601 tgtggagacg ttgatactat gattttggat aagacaggta cgattactta tgggaataga
    18661 cttgcatcag aatttatagc agttggaaat gcagattcaa aagatttaat aaattattct
    18721 gttatgtgtt cattaaaaga tgatacacca gaaggaaaat ctatagttga tttaggtatg
    18781 aaattaggtt caacaggtaa gacaaaagag gcagaggaag ctgagtttgt agaattttct
    18841 gcacaaacta gaatgagtgg tattaactta gctgatggta gagctataag aaaaggtgct
    18901 tatgatagca taataaaaag agtaaaagaa tctggtggta cagtgccaga agatttagaa
    18961 gaaaatgtaa atcgagtagc taaactagga ggaacacctt tagtagtgtg tgtagataat
    19021 gagatatatg gaattatcta cttaaaagat acagtaaaat cagggcttgt agaaagattt
    19081 gctagacttc gagagatagg aataaagaca ataatgtgta caggggataa tcccttgaca
    19141 gcagctacaa ttgcaagaga agctggagta gatggattta ttgcagaatg taaaccagaa
    19201 gataaaatag atgcaataaa aaaagaacaa ttagagggta aaatagttgc aatgacaggt
    19261 gatggaacaa atgatgctcc tgcacttgct caggcagatg taggtcttgc aatgaatagt
    19321 ggtacaacat ctgcaaaaga agcagcaaat atggtagatt tagattcaga cccaactaag
    19381 atattggaag ttgttgaaat aggaaaacag cttttaataa ctcgtggggc tttgacaaca
    19441 tttagtatag caaatgatgt tgcaaaatat tttgcgatta taccagctat atttactctt
    19501 gcaatacctc aaatggagat attaaatgta atgaaacttt ctacgtcatt tagtgcgata
    19561 ttatcagctt taatatttaa tgctataatt atcccatgtt taatacctct tgcaatgaag
    19621 ggagtaaaat atagacctat gaaatcacaa gctatgttaa tgagaaatat gcttatattt
    19681 ggtcttggtg gagttatagt accattttta ggaataaaat taattgattt attgattaca
    19741 cctttagtaa tggttcttaa tttaggttaa taaatggagg atataaaaat gaaaacatta
    19801 aagccagcat tacttgtaag tattgtattg ttagttgttt gtggacttgt atatccactt
    19861 gttttgacag gtgtaagtca agttgcattt aaagataaag ccaatggaag tatgatagaa
    19921 gtaaatggtg taaaagtagg ttcagaactt attggtcaaa gctttacaga tgcgagattc
    19981 tttaagggaa gagtatcatc agtaaactat aatacttata caaaagaaga tttagtacca
    20041 gataaagatg gaaatacatc ttatggaggt gtatcatcag ggtcttttaa ttatggagct
    20101 acaaatccag aacttcatga tagagtacaa aaagatatag aaaagttttt aaaggataat
    20161 ccaactgtca aaagagagga tataccaaca gatttactta cagcatcagg ttcaggactt
    20221 gaccctaata taagtccagc ctctgcaaaa attcagatac cagctatagc aaaagcgtct
    20281 ggaatatcag aaagtaaatt acaaaaaatt gtagatgata atacttccaa aaaacttttt
    20341 ggagttttag gtgaagatag agttaatgta ttaaaagtta atgtagaggt cgcaaaaata
    20401 ttaggtctta tatagtattt tgtggaattt tagcaacaaa atattactca agatttaatt
    20461 taaaggttaa attttaaaga gtgaaaatcg ataatgattt tcactttttt atttgaatat
    20521 tactaatatt tggaataaag tgattgtaag tataaaatcc aaaaaaaggt tgcattatca
    20581 aaatgataat actataatat atttatcgtt atcaatttga taatagattt ggacatatag
    20641 gaggaaatag tatgttatat aataacgcat tagagttgat aggaaacaca cctgtagtaa
    20701 ggctgaataa tttaggctgt actaatgggt gttctaacat atatgtaaaa ttagaaaaag
    20761 taaatccagc aggaagtata aaagatagag ctgtttatga aatgttagag ggcttagagc
    20821 aaagaggaga attaaaaaag ggagatgtac tagttgaagc aactagtgga aatactggta
    20881 ttgcattatc tatgatagga aaattaaaag gatatgaagt agtaatcgta atgcccgaaa
    20941 caatgagcgt tgagagaaga gatttaatga aggcttatgg agcaaatttg gtgcttacag
    21001 atggtaaagc tggaatggca ggttccatag aaaaagcaaa tgaactttta aaagaaaatc
    21061 caaactataa aagcttaaaa caatttgaaa ataaagataa tccaaatgca cattataaaa
    21121 caacagcagt tgaaattatg aatgatgtca aagatttaga tatattcgta tgtggagttg
    21181 gaacaggtgg tactttaata ggaactgcaa gatatttaaa agaacaaaat ccaaatataa
    21241 gagtaattgc acttgaacca aaaaaatctc cagctatatc agaaaacaag actggacctc
    21301 ataaaataca aggaataggt gctaactttg ttcctgaaaa ttatgattct agtgtagttg
    21361 atgaagtaat attagtagat gatgaagatg catttgatac agttaaatta cttgcagcaa
    21421 aagagggaat tttagtaggg atatcttctg gagcaaatat atttggtgct atagagatgg
    21481 caaaaaagta tccagataaa aagatagtta cagtagctcc agatggagtt gataagtata
    21541 tgtctatggg aatattttaa taattttatt tgagggagtg aatactttgt ttaagaaaat
    21601 aaataaagat attgaatata taatgaagaa tgatccagca gctaggtcta agatagaagt
    21661 ttttttactt tatccatcag ttcatgcaat gataatgcat aggatggctc atgctcttta
    21721 taagaagaag aagcttttta cagcaagatt aatatcccag atatccagat ttatgactgg
    21781 catagaaata catcctggtg ctaaaatggg ggaaggtata ttgatagacc atggaatggg
    21841 tgttgtaatt ggagagacag cggaagtagg taatagggtg acaatatatc aaggagctac
    21901 tttaggagct acaggaaaag atactggaaa gagacatcca actgttggtg atgatgtatt
    21961 aattggtgct ggaacaaaaa tactaggacc tttaaatata ggttcaaatt caaaaattgg
    22021 tgcaaattct gttgttgtta aggatgtacc taatggtgca acagttgttg gtataccagc
    22081 aaaaatagta aaaataagaa acctagaacc tgtaaaaaag aataaaaaag aagtgtccta
    22141 tgagtatgat gaattagata atgtatatta tatataggat ttatataact ataaaataaa
    22201 ctttataaaa attattttaa aaggtatttt tttcaaattt gaggacataa taaaaaagaa
    22261 ctgaatgtta cagttttggt tcatcaatct ttgataaata agattttaaa tttgtagcgt
    22321 ctaggaggat tttattatga aagcaaatgt taatcaagat acttgtatag gttgtggatt
    22381 atgtccatca atatgtccag aagtatttga tatgaaggat gatgggaaat cacatgttat
    22441 agttgatgaa gtaccaagtg atgctgaaga atcagcagca gaagctagag aaagctgtcc
    22501 agttgatgca atagatgtgc attaataaaa taaatgccta taaaaattga attttcaatt
    22561 tttataggca tttgtctttt attcagttag tatttcaaca cctgtttctg taactaaaac
    22621 catacattcc cattgagcag ataatttacc atcttttgta taaatagtcc aattattttc
    22681 ttcatcaaca aaaatttcgt gagttccttc atttaccata ggttctattg tgaatatcat
    22741 cccaggaacc aatagcatct cagtcccttt tttagataca taacttacaa aagggtcttc
    22801 atgaaagctt aatccaactc catgaccacc tatttctcta acaacagagt atccattttt
    22861 ctttgcataa gagttgatag catcacctat atctcctaaa aatccccatg gtttggcaac
    22921 ttcaagacct ttttggacac attcctttgt aacttgaact aatttttttg cattttcatt
    22981 aacattacct atcataaaca ttcttgaagc atctgaatag tatccattaa aaatagtaga
    23041 aacatctaca tttataatat ctccatcttt taagataatg tccttacttg gaataccatg
    23101 acaaacttca ttatttactg atgtacatac acttttagga aatccattat agtctagtgg
    23161 agcagggata gctccatttt gtagtgtaaa gtcatgaacc aacttattta tatcttctgt
    23221 agacattcca atttcgattt tatctgaaat ataatccaaa atttttgtgt ttattacagc
    23281 actttttttt atttcctcaa tttgactttc attttttata atatcatgag ttggtacaat
    23341 atgacctaac ttagcaaatg aatctatttt attatccata tccatatgac attttttata
    23401 ttttttagta cttccacacc aacagctatc atttctattt aacttcataa cttttcatcc
    23461 ttcttttatt atttatttaa attatgggtt acataaacta ttttaaaaca taaccattat
    23521 aaatattata acataaatac taagaaatcc tttatagata gtgatttatt caaagtataa
    23581 attattatat ggttattgtt gatgaaaaga ggatagttaa atgtattatt ggatattagc
    23641 gcacttaata gtttagttca agtttttcaa gaaaatcata tgttagagga caattttcct
    23701 ttaaagtatt ttttgaatct tcatcaagat aataatgtac aaatgattct gcaaaaaatt
    23761 cttctataaa cttgcttata tatgcatgtg caacttgctt agggtcataa agcttatatc
    23821 tttcctgagc aaatacttcc ataaattctt cagaatttga ttttttattt aaaacatttt
    23881 tatctatagc atgtgcagtt tcatgtaatt ctaaattttt tgatgaatgt acatttgcat
    23941 agctaggatt actataacct attttagcca ctatagaatt atttctatat ataccaggta
    24001 catctttcca agtcttgcct gatcttaccc aacatggagg taattgatat tttaaatcac
    24061 taaattctgg ttcatcagtt agatttgaat ttattaattt tatttttata tccttttctt
    24121 taagtgtctg taaatattta atatttattt ttgcaagtct gcttttcata ttttcaactt
    24181 catctttatc ataattcaag tcatcaggaa gtataagcat ttgttcaatt atatctatac
    24241 tactgtcttt tatattttca gattcttcat caaatttata ttgaagagta ttattttcat
    24301 agatagttat atttgtatta ttttctatag aataagagtg aatatcctct aaatctaaaa
    24361 tattcatttg ttgtaaaata tgttttgttt cgccactcca tactactaaa gaaagtgaat
    24421 taaaattaat tagtggattt tcttttgctt ttatatcatt gcttatatct acatcaaata
    24481 catattcaat tgagtcttct atgttaagac tatctgtatt ctttttaata tataaatacg
    24541 cttgttttaa gtctatataa atctcaccta aagattcgtc ataaaattct gataaattat
    24601 tagtaaagag ttcttcactt aaaagttcat ttttatcagt tatactttca attaaaatat
    24661 taatttcttt tatcatatcg taaatactta tttttctatt tgctttttca ctagatacat
    24721 tgcatggcgc aagagcaatg caataaaaat ctttttcttt tttataaaag gctttaagtg
    24781 attttgataa aagtgtaaag tctacaccta tctgtaagtt gaccttaagt gagtcatttt
    24841 gtaataattc agtattattt cttttagctg tatttaaatt gttttccata atcattgccc
    24901 cctttttatt agggtatcat aattttttta tatgtgtcaa tttgtttttt tgaaaattat
    24961 aatttttttg aaaattttat tttttataat ttgtgaattt tttattatag aaataaatat
    25021 gttattatta tgtcaaaatt tagcattaga ttcatgtaga gtatgtttta tacatatatt
    25081 ataattaatt ctttgaagat tgcatattca aaatacacac catttttttt aattctataa
    25141 tataatattt atatatttaa tgttaggatg tgatttaagg tgtattttac atatattata
    25201 agatgtaaag atgattctct atacactgga tataccagta atatagttag aagaatgaat
    25261 gaacataagt taggaattaa ttcaaaatac acaagagcaa agggatttga aaaactagaa
    25321 gtttattttg tgaccaacac aaaaagcaat gctatgaagt tagaatacta tataaaaaaa
    25381 ttaactagaa ataaaaaatt gtctataata aaaaacccaa gtatacttat aaatttaatt
    25441 gataataaag aagattatat tattggtaag aaaatagaac aattaacata aatatttata
    25501 gtaacattat aatgggtgca tatggtgtaa aaacttgaca ataaatacta ttgtaatata
    25561 atgaagttat aaatatagta aattaaaata gctaggggag ccaagagctg agaggtatac
    25621 cgacccttac acctgatctg gataatacca gcgtaggaaa gcttagtaaa aattcaagta
    25681 tgtattattt gtgatatatg ctatttctaa gctataccta ttgtaggtat agctttttta
    25741 attaagttat ttaaattaaa ctttaggagg caacaatgag taattataaa ataccaacac
    25801 ttacaatagc cggctctgat tcatctggag gagctgggat tcaggctgat ttgaaaacgt
    25861 ttagtgcaat tggtacttat ggtatgagtg taataacagc tataacagca cagaatacta
    25921 aaggagtttt tgctgtagag gatttaaata agaaaataat aaaaaaacaa atagaggcag
    25981 tctttgaaga tatacctcca agagctgtaa aaataggaat ggtttcaagt cctgagatta
    26041 tacttgaaat agttgagaat ctaaagaaat acaatccaaa atatttggtt gtggacccag
    26101 taatgatatc taaaagtgga tattatctat taaagccaga ggcaaaagaa aacttaatta
    26161 agtatttgat accacttgca tacataatta caccaaatat accagaggca gaagaaataa
    26221 caggaataaa aatacataat gtagatgata tgaagagagt aggagaagaa atactacaac
    26281 ttggacctaa atttgtactt atgaaaggag gtcatttaga tggagaagca gtggatattt
    26341 tagttggtaa aaatatattt aaagtttata aaagtgaaag aattgataaa aaaaatacac
    26401 atggaacagg gtgcacatta tcttctgcaa taacatctta tctagcatta ggatatgaaa
    26461 taacagaagc agtaaatcta agtaaaatct atataacaga agcaataaaa agaagttttg
    26521 atataggtca tggagtagga ccagtacatc atttttataa atttgagtaa taaaaaaata
    26581 ttggaggtaa aatatgtata atttaattaa agatgtaaaa aaattaaatc cattggtaat
    26641 tcattatact aataatgtaa ctataaatga ttgtgctaat gtaactttag ctgtaggagc
    26701 aagtcctctt atgagttttt catatgagga agtagaagaa atggtaagtg tagcaaactc
    26761 tgtagtaata aatataggaa ctatgaactc aaatatgttg gatttattcc tattagctgg
    26821 aaaagcagca aataagtaca ataaacctgt tgttttggac ccagttggag tatttgcaag
    26881 caaagcgaga gcagaactta caagtagact tttaaatgaa gtcaaattta gtgttgttaa
    26941 agggaatgta tcagaaataa agtttatagg tggctttaat gtaaagggta aaggtgtaga
    27001 ttcatttgat gaagaagaag attctactga gataataaga aagattgctg aaaagcttga
    27061 atgtgtagtt gtagcaactg gaaaaataga tataataact aatggtaaag gtacatataa
    27121 aataaacaat ggaactgata aattaaaagg aattacagga actggatgta tgactgctag
    27181 cttgattgca agttttatgg ctgttactga gaatatatta gaagcagcaa caatgggtgt
    27241 tcttacaatg tctttaagtg gggaattagc taatttaaat aatccaccaa taggtacatt
    27301 taaagaaaat cttatgaatg ctatttatca aatggatata gatactttaa gtaaaaattc
    27361 taatattgaa tttttaaatt aataaagagt aagggagact taaaatgatt gataaagaat
    27421 ctttaaaaaa atgtttaaag ttgtatttag taactgactc tgaaatgctt aaaggtagag
    27481 acttttataa atgtcttgaa gatgcaatat cttctggaat aacaactgta caacttagag
    27541 aaaaaaatgc ttctggaaga gagtttttaa gaaaagctat gaaacttaga gaaataacta
    27601 aaagatatgg tgttaagttt ataataaatg atagagtgga tatagcactt atttgtgatg
    27661 cagatggagt acatgtagga cagagtgaca ttgatgttag agaggttaga aagcttatag
    27721 gaaacaataa aattctagga gtatcagcaa gaactttaga agaagctatt tgtgcaaaaa
    27781 atgatggcgc agactattta ggtgtagggt ctatattcac aacatctact aaattagatg
    27841 caaaatcagc ttcgtttgaa actgttaaag aaattaaaga aaaagtagac atgccatttg
    27901 tactaattgg aggtataaat ttagacaata tagataaact taaatgttta gaaagtgacg
    27961 ggtatgctat aatatcagct atattaaaag ctgaagatat ctctaaagaa gtggaaaagt
    28021 ggacattaaa aatataaaat tggctctggt agtgaaaaaa atggaaaaat ttgatataat
    28081 ctaagagtaa aatttaagca attataaatg ataaactttt ctacatatac tttttaatca
    28141 agatatatgt agatttggtt aaaaaggagc tataaatgat taggatattg ttagtgtgtg
    28201 ttggaggcat gtcttctacc ctattggtaa ataaaatgga gaaggatgca aaaaaaagaa
    28261 atatagactg taaaatatgg gcagttggag aaggagatat aaaatcggag cttgataact
    28321 ttgatatttt acttcttgga ccacaactta gatttatgct tgatgacgta aagtctatag
    28381 ttggagatag agctccagta tctataatag atatggtaaa ctatggcact tgtaatggtc
    28441 atgctgtgtt aaattcggtt ttagaaatat taaaataaat aataaaagtg gattctatat
    28501 aatagagtcc atttttatta tttgttatta ataggcttaa aacttagctt accatttctt
    28561 tttttaatct ccacatagca agtgaaaaac ttgaacagca caatattaaa aatagtagga
    28621 taaaaggcag tatatctcca ataagaatag tctcaccaaa tattaagcta cgtaaagcgt
    28681 taataacatg ggtaaatgga ttgagcatca ctgctacttt taatcctcca gataaacttt
    28741 ctatagggaa aagagctgaa cttaaaaaga aaataggaag tacaattgca gtcataattg
    28801 tttcataaac tatttcattt ggcaataata aacttataga ataagctaga cttgataaaa
    28861 agaaggctgt cataaatatc agtactatca taagtaggat tccaccaatg ccagattcta
    28921 tccttactga gaagaatata cttactatac acaaaatagt tacttctatg aaagaaacta
    28981 agatagcttc taataattga ccaaggacga ttgaatacct gctgataggt gcaattaaga
    29041 ctctatagaa acttccactg ttcttcatta taaagtttat aataccacca ctactacaag
    29101 aagaaaacac aaccagtaca atgatacctg gtagtataaa agcagtataa ttattgatat
    29161 ttatattatt catagtttgg tttgcaatag aactataaag cacaagccaa agaaaaggtt
    29221 gtaatatagt aactacaaat gagattggat ttttaaaacg ccacttcata ctacgccata
    29281 agatatttaa cattcccatt cctcctttaa gcttttttta gaacttgtaa gtgctaaaaa
    29341 tacatcttcg agacttggct ctacaatttc tattgcatca aattctatat catgttctaa
    29401 aagccattta tttattaaag taaaagcagt tctactatcg tttacactta taaaaattga
    29461 attttctcgt acgctcataa actttactaa accagtactt ttaattgaat ctttatattt
    29521 ttttatatct tcagtattat gaaaagttat acgtagtata ttttgtctaa tgtaactacg
    29581 taaacttgat ggtgttcctt gtgctaaatc ctttccattc ttcataatac aaatattatc
    29641 actcaattgt tcagcttctt caagataatg agtagttaga aatatagttg tgccatactc
    29701 atctctaatt tttaataaca tatcccacat agattttctt gaatcgacat ccataccaac
    29761 agttggttca tctaaaaata ggattttagg agatgatacc atattcatag ctatgtccaa
    29821 tctacgtttt acaccccctg aatatgatga agtaggatat tttaagtaac tagataagtc
    29881 aaacttatca attaaagagt ctattctttg ttttgcaatc tgtggttcta ctttatacat
    29941 tttactttga aataccatat tttccataag ggataaatgt tcatcaatag agatttgctg
    30001 tgctacacaa gcaatttgag tacgtatcca agaagaatta tctactaaat cttttccaaa
    30061 catttttaca tttccagatg taggtttgta aaaggtagtc aaaatattta taagagaaga
    30121 tttaccagca ccattaggac caagtaaaga aaaaatttct ccagcattta cattaaagct
    30181 tagaccattt aaagctttca caccattttt atattctttt actaaattgt ctatttcaat
    30241 cgctaacata tattattcct cctctttaag tggaaatatt atctctgtaa tatagttatc
    30301 tgggtttcct tttatcaaca tacctggtcc tttaataaat acttctctcc aaggagtttg
    30361 tatttttata ttattttcat gaatatattt aaatatcatt tcatacgttt ttggcaaatt
    30421 actataagag cctgtgtgag taaaaaataa agcttttgtt ttaggaaatt cttttgtagt
    30481 tatacccata cgatttggag tttcagcagt tggaacacat aattccattt ctgcaacacc
    30541 agttttttgg tcaacatcat agtagcaaaa gaatggtgca ccgttagact ttccttttat
    30601 agctttaaat acatttggaa aatactttgt tgcctcagtc ataggtccat tataacgcat
    30661 ggtagccact gtgactgatt cgatattttt gatttcaatt ttgcaattca tttgtttacc
    30721 tcctaatgtg tgttcatatt cttactagat ttttaagcat taatacatat aagattttga
    30781 ttagttgaaa acatataatc ttatctcgtt tgcttgtttt caagtctaac ataacataaa
    30841 atatatatcc tctcatttga tgctccattt tgtaaagtta ttatttaagc tttactttag
    30901 attttttagc aaattaaaat aaagcaattt ataaaataag tatttacaaa ttaagtgtat
    30961 taatcgtata atacacttaa taggatacta gataaagtct gaaataaagg cgtatttttt
    31021 taaagtaagt gtactatcgt attaatacac tagaatagga ggaatcatga attttgaatt
    31081 agataataca actcccattt atttgcaaat agtaaagtat ataaagagac aaatagtaac
    31141 aggagagttg aaaccaggag agacaatacc atcaagaaga gaaatggcac ttaatctaaa
    31201 agtaaactta aatacagttc aaagagcata taaggagatg ggtgatatga atataataaa
    31261 tacttttaaa aattatcaaa gcagtgtaac agttgatgaa aatatattaa aaaatttaaa
    31321 attagagctt ataaatgaat cactatctgt ttttatagaa gatatgaaag caataaatgt
    31381 tagcaaagaa gaagttttaa aaataataga agataagtat tagtttttta acaaatagaa
    31441 aacttagttt agaaagttta tttataagca tattggatgt ggaggatagt aaatatgata
    31501 gaaataaaga atgtcagcaa aacatataaa aggatgcaag ggcttaaaat aagaaagata
    31561 gaagctttaa aaaatgtaag ttttaatata gaaaagggaa aaataactgc attacttggt
    31621 ataaatggtg ttggtaaatc aaccatgtta aaagcaatag caggacttat aaacattgat
    31681 agtggagaaa ttcgtataga tggagaaaaa ataaatgaaa aagtatacaa taaattggct
    31741 tttgttccag atgtacaatc tcactttagc aatacaacaa taaaagaaac atttgaattt
    31801 atggaaattt tttattcaaa gtggaataaa gaaaaatcaa aagaaatgat ggacatattt
    31861 aaattggatg aagatgaaat aattgataac ttgtcaaaag gaaacattgc aagagtaaaa
    31921 ttaatacttg gattttgcca agacccagag tacatacttc ttgatgaacc atttacagga
    31981 attgatttgt ttaagaggga agagtttata ggagtaatag cgcaatatat ggaggaaaat
    32041 caagccatta tcataactac tcatgagata gtagagatag aaagtttagt tgatgaggtt
    32101 gtaattcttg atgaagggca gattataact tcatttaatg cagaagaatt aagagaaaga
    32161 gaaggtaaat ctatattaga taagatgagg gaggtatata agaatgaata aacttctata
    32221 tctaataaat gtagatttga gaagaagcaa taagttttat atagcttata tatcattttt
    32281 ttcattaatt acacttagtt taaatttatt cgaaattaat aaatttaaaa attctaaatt
    32341 tattatgaac ttagcaatag aagattttgg aggtatattt tatggactag ggatacttag
    32401 taatcttggt tttatccaaa gtatattgtt ctttgggata ttgggacttt ttatatacta
    32461 tatttttatg tggaaaagag agttcttttc aaataatcaa agtatttata cacttatgat
    32521 gttacctcaa aataagttta agatttgtat atctaaatca atagccttga taacaatgat
    32581 atatggtttt ttgataagtc agacagcaac attatttata tgtaaatata tatttaattt
    32641 catttttaga aatatgccta taatcaatat gaactttgcc aaagatttat attatttaaa
    32701 cttgaagagt ataccaattg attttatctc ttttatggct atttatgtat ttttactact
    32761 tatagctatt tctattgtaa attgctgtat attatttatc ttttcctata taaataaatt
    32821 ttatgtaatt ttaatcactt tgctgattat agcaggctta tatttttcaa caatatatat
    32881 aaatataatc actttattta gaaaatatta taatcttata ggatttcaat ttaacaattt
    32941 agtagcaggg ttattaagtt ttttaattat aatgtttatt ctaaatggaa tatcttattt
    33001 gctaattaaa aagaaagtat ctctttaagg aggggtggta tgaaattaaa atctaaaata
    33061 tctatattta ttatattttt gactttagca atatatttta gtataggttt attaaataat
    33121 gaagataatt taaagataaa aactataaaa ggtgactcta atgaattaga ccatataaac
    33181 ataaattttg gatatgcttt gaatggatat ataaattcat attatacaat aaatggaagt
    33241 aacaaaacca aaaagactga attaataaaa ctacaaaagg atagtaagaa cacaaataat
    33301 ttaattgatg tatctagtgg ttcagattta attgctcatg ttggatttga aatgaatgag
    33361 gagtcaaaag atataaactt tgtgatagat gagaaaaaag aagatttaga aaaaggtgta
    33421 tttccatcag aaggtagtga taaagaaatt gaatatgaaa aattagatat gaataatttt
    33481 acaaggacaa gatataaagt agataaaagt acagatgatt attatgcaaa gatactagca
    33541 tcaaaaagat ataaaaaata cttatatgta tctgtacttt atgctacaag tgattcatca
    33601 gaaaataaca aagaatattc aagtactata gatataataa aaattaatcc agaaaataaa
    33661 aaaatcaaga ctataaaaag tataaattta agtaattatt tttccgaaaa ataccaaaac
    33721 atagagaaca taggtgtaag ttatgctagc aaatatgagg ataagatgta tattttagta
    33781 aatgtactaa atacaaacat aggtgataat agtaattcta aatttcattt acttgagtat
    33841 aatcttgaag aaaataagga aagcataatg gaattaaaaa ctgatagcaa aatggcttta
    33901 gcaaaagcaa agttagaagc taataaatta tatatggtaa tgtcgaatga ttatgataat
    33961 agttcaatta cagagttaaa tttacttacc tataatatat tagataaaag cttagatgaa
    34021 gataaatatg ttttagataa tagagaaaaa agaggaatta gaagtattga aattgattca
    34081 aataaaatcg ttgcatatac atcaaggcta aactctatat tatcttggga tgataaattt
    34141 atgctatata taataaataa aaattctaag gaaattgtat atgaaggaga attacaattt
    34201 aacagttcaa atagtatgtt agaatttgaa ataaagtagg tgagttgatg aaagatttaa
    34261 taagattatt cgaatttgaa ttaaaaagaa atataaagaa ttatatattt ataataattt
    34321 gttgttgttc ttttgtaatt ttaaacatag taaaaaattt aaatgactat aattacataa
    34381 tagaaaatgc agttaaaagt gaacagttaa caaaaatcgg aaatacgata gaaacggtaa
    34441 atgttacagg tttctcaagc tttagaaata taatgggttc tacagaatcg tggtttatgt
    34501 ttggtataat tgcatgtatt tgctatgctt tttttatttg gtatagagac tttaatggta
    34561 gaagtaaatc tatatataca cttataatgc tacctaaaaa tagaatcaat atttatatat
    34621 ctaaattatt aaatatatta tttctagtgt atagctatac agtagtactt acaatatctt
    34681 tgtttattgc aagtaagttg ttgcctagac atatgcttgg taatgtcaca aactatggtt
    34741 ttgtacaaga aacaatatat gagttaaaaa tgttacttcc atatagcttt gaaatactat
    34801 ttgtagagta tatattttta ttgataggat ttgtatctgt agtatttaca tcaattctta
    34861 taaataaatc tatttataaa gtaagcactt taataagttt tctattttta gttatagaaa
    34921 ttttagtgtt tataatttct atagaattta ttatacctta cgaatacagt gatgtattta
    34981 ctgttctata ttcaagtata aacatatttg tatgtagtct tatatctaat aaacttttga
    35041 agcaaaagat tgacttttag gagggatatt atgaaagcaa aaaatatagg aaaatataca
    35101 atatgtttta taatagtatg ttttttaatg attactatga ccttaatatt gagttatttt
    35161 aataaggata aactatctgt aaaaacttta aaaggcaatg taaaagatat agggagagta
    35221 agtgtagtat atacacctga tataagcaaa ttttcttatg aggaggtaat tataagtaaa
    35281 aatggagtaa gaaataatac aaacccaaaa tcaagaatta gaaatgatta tttaaatatt
    35341 gacaaaaaat acagtgactt tgttaatgat aaaggaaaag aatttatata taaagatgat
    35401 ttgaatatag gagaagcgta tacctctgtt aagtctgatt tagtacaagg aatgaatgct
    35461 ttaaatgatt gtataaaggt ttcaaataaa aatttaaaaa gtggggtaga agaaaatttt
    35521 gatattaatt taaataagtc tgattttaaa gaaaatagtt ggaaaacctt atttaacaaa
    35581 atatataaag gtaatttata tatggtaatt agtgaaacta atatttcagg ttctaaagtc
    35641 aataatattt gtatattaaa gatagatata aaaaataagt cttataaatt attaaataga
    35701 tttaatttag gattacagaa tggagaacaa caaaatatca atgaaattaa attttctatt
    35761 ggaagtaaat tatacttaga aatagtaaat aataaaagta aaaatggata tattgaagga
    35821 catgatagtt actctaactt tattatatat gatatagaag ataacacttt taatataagt
    35881 aataaattta tggataatct aaacaaagaa aagaatgcaa atccaaagga gattggctta
    35941 ttaagtaaaa ctaagctaga ttatatggta aaaaataata aattgaatct tatagttacg
    36001 gatatgagta attccataac taatcttgtt tatgatatta attctaatga gattaaatta
    36061 gaagattatg agatacttga tttaaaagta gattataatg aagcatcatc tggagttagg
    36121 aaagttaagc tactggatga taagatatat tctatttcag gtattaagaa cagtatatca
    36181 ggagaattaa aaggatttaa aggggttgtt gatgtagtcg gaactaagcc agtaaaattt
    36241 caagtatttg atatgaaact taaaaagaat atttatgaag ctgagctaat aaatggagat
    36301 ataagtttac aagaaaagtt attttttgtt gcaaattaag tgttagaatt aattttagaa
    36361 ctttaaactt ttatatgtat cacagataag tataagtaag ggagtgtctc aaaataaact
    36421 ttttagctca tgagacactt tttttatatg aaatcaaata tattttcatt gtttagattt
    36481 attttgataa tgaaaaaaag attatcttta ttttaagaaa gacatttatt tataattata
    36541 tacaaaaata ttttttaatg tttttgtgta taattataac aatttaattt atattaatgc
    36601 acttaaattt gaaatagaat gcttatagtg gtaaaattaa ttattagaat attagaaata
    36661 ataaataaat aatacattgt acttaaaagg gggagaaatt taagatgaac aaaaaatata
    36721 ttaaagcagg gaatttaatt gatggaaccg gaaatagtat tatgcaaaat aagggtataa
    36781 ttattgatgg agatactata gttgaaattg aagatataag agatgattta aatggatatg
    36841 atgtgtacga ttacttagat aaaactgtta tgccaggcat tatgaattgt catgttcact
    36901 tgacaatgga gccagttgga aatccaaaga tatattatga taatgtatca gatgtagagc
    36961 ttgtagtaaa tacgataaaa caacttgatg cttatttgga ttcaggagta acatatatta
    37021 gaagcttagg ttgtcccaaa tatgtggatg tacaacttaa aaatcttata gacaaagggt
    37081 ctatagatgg tcctggtata gttacttcag gtccagttat atgtatgaca ggagggcatg
    37141 gatattattt tggtattgaa agtgatggag tggatgaatg tagaaaatca gccagaacag
    37201 ttttaaaaaa tggagtagat tgtgtaaaga taatggcaac tggaggtgta acaactgatg
    37261 gagttgagcc agggtcacca caattaactt tggaggaaat gaaggctgct gtagatgaag
    37321 ctataaaagc aggtaaaata actgccacac atgcacaagg aagaactggt ataaaaaatg
    37381 cagtgcttgc aggaattact tctatagaac atggtgttta tttagatgat gaaataattg
    37441 atttgatgct tgaaagagga acttacttag ttccaactgt ggctgcacca tattttattc
    37501 taaatgcagg aaaagaaagt ggaataactg aagctactct tagaaagtgt gagattgttg
    37561 ccattccaca caaagagtca ttcctaaaag catataaaaa aggaattaaa attgcagttg
    37621 gttctgatgc aggaacttct tataatgaac atggaaaaac atattatgaa atgaaactaa
    37681 tgtcagatta tggtatggat aatatggata taatagttgc tgctacaaaa acagcatctg
    37741 aacttttaag aattgataaa aattatggaa ctctagaaaa aggaaagaaa gcagatgtta
    37801 tagttgtaaa tggaaatcca gtagagaata tagacgtact tgcagatgtg ttagcagtat
    37861 ttaaacttgg taaaaaagtt agataaatag tataaaaata aaaaagagtg tctaaagaaa
    37921 tttttaaata attatagaca ctctttttta ttagtaataa ttaaatcttt tatactttag
    37981 aaaatagatt ctattttata tttagatata actctttaaa atcattctta tgcaatataa
    38041 tctatagaat ctacacatac aaagtatatt cttgaatcat tagaatttcc aagtactata
    38101 acatcatttt tcttacctag aacttcaaca ccagttagaa ccaaactacc agctactaca
    38161 gtaacttgat tatttatatt tgacatataa agattatcta ggataccttt attacaacag
    38221 caatcatcac aatcgcagtt acaattacat tctttgtaat gttttttatc aagatagtaa
    38281 cctaaagatg ctatgaaatc ttcataatct gcaggtgtaa tatcaaatgc aacagcttta
    38341 agattacaca atgatgctaa atctacgttt gctaatggag tagatgcagc aagtataaaa
    38401 tcaattatag cagcaagtat tgcatctaat atagccccaa ggtctatcgt aggaggaata
    38461 actgcatcaa taagtgcaat taattcagct actcctggta tagttcctat agtattaatt
    38521 aatccctcaa gagttaaagg gactggaata ggataagata ctctaccagc tatatctatt
    38581 aaatcacagt tacaagcaga aaatctttca aaagtaccat caagttcaga taaattatct
    38641 tttggaggag ctgaaagatc tatacctacc aaattagcac ctactataaa gaaatctgag
    38701 ataaaagcaa attgattaaa gtttacaaaa ggtcttagag catcatatct tagaagttct
    38761 aaggcctctc tcatactttt tttacaacaa cattgtttta ttttaggttc tttatattta
    38821 tttggataat tatagtatct atcagctact tgataatttt catagtatct ttcatttgta
    38881 tttggataat cttcctcata ttcttgtgta aatctaaagt cctctctaca tttattattt
    38941 tccactaaat acactccttt tatattttaa tttaaatgta tagataatta agcttatcta
    39001 tatagtaata ttatatttat aatgtaaaaa aatgttacaa aagatattat aaacaaataa
    39061 aaaataataa tttgtcagat aaacttgtaa atttttatga ataatccatt ctaaaacaaa
    39121 aaactgtgta taaaaaaggt ttatatgtta tatttatata aatataacat atgaacgaga
    39181 aaggagtggt ttgataaatg attgaggtag ataaattgtg taagtctttt acaagggttg
    39241 taaaagatga taagaataaa agttcaataa gaaagctaaa gaaagtaaaa actaaaaaag
    39301 aagaattttt tgctgtaaat aatgtttcat ttaaagttat ggaaggtgaa attgttggaa
    39361 tattaggtcc aaatggtgca ggaaagacta cattacttag aatgttaggt ggcatattaa
    39421 caccaacatc aggaagtata aatatttctg gatatgatta ttcaatagat agaaattcag
    39481 caaaaaaaga aataggttat ctctctggaa atacaaaact atatggaagg ctttctccga
    39541 gagaacttct aacaactttt gcaagtctat atgagatgtc aaaagaagat atagaagaat
    39601 caattgaaaa tattgtaaaa ataatggata tgagtgaatt tatagataat agaattgaaa
    39661 atctatcaac tggtcagact caaagaacat ctatagctcg ttgtttaata cattctccaa
    39721 aagtatatat ttttgatgag ccaacactag gtctggatgt tttaagtagt gcatctatta
    39781 tagattttat gaagaatgaa aaactaaggg gaaaaactgt tctttactca actcattata
    39841 tggaagaagc agaaacttta tgtgacaaga tttttatgat tcacaatggg aaaataattg
    39901 catcaggaac accacagagt ttaaaagagg aatctggagt aaataatttg agagatgtat
    39961 tcatagaact tgccagaaag gaggacattt aaatgagaag taagattgta aaatacatat
    40021 ttaaaaaaga aatgttagac atattgagag ataaaaagac tttatttatg atgattgttg
    40081 tgccacttct tttatatcct ttacttatgt tattaatgat tcaagtaatg aatatgtctg
    40141 caagtagtat gaatagtaag gacattaata tagcttttaa taataaacct aataaggttt
    40201 tagtatccat gattgaagat gataatttag aaaaagatac taaaaatact tcaaatgata
    40261 aaggcaaaat aagagtgtta gatgtagata actataaaaa gtcattagaa gaaaataaaa
    40321 ttgatgctta tataaagatg gaagaaaaaa aatcatctat aaattatcaa atatatataa
    40381 attcttctca agaaaattct tctaatgcac taaaaagaat tgaaactgtt ttggataaat
    40441 ataaaagatt taccatagaa aaaactttat ctgaaaaagg attagatgta caagctactt
    40501 tagaaccaat aacatatagc actgtagatg ttgcaaagac ggaagaagtg gcaggatact
    40561 ttttaggtca gatacttcca tttatattaa taataggagt tttactaggt tcaatatatc
    40621 cagcaataga tgttatggct ggagaaaagg aaagaggtac attagaaaca ttatttacac
    40681 tcccaatatc aaacttagaa ctggttatgg gaaaatatat ggcagtttct cttagtgcaa
    40741 tagtaacagc aattttaaac attttatcta tgggactgac tatggcattt attttagtta
    40801 gtggaggtat tagtagccaa tttggttttg gaaactttaa ttatggagat ttagtcttac
    40861 caattataac tactttaatt tgcatatgtc ttttttcaat ggtagtttca gcaataagta
    40921 tgtgtgtatg ttcattagca aaaagtttta aagatgctca aaactacata acacctctta
    40981 tgttaattat tatgatacca tcatatgttt ctatgatacc aaatatagta ttagatagag
    41041 taacagctgt aatacctgta gtaaatatat ctttacttat aaaaagtgta ttatctttta
    41101 aaagcgattt aaatttaata gccttagttt tagcatcaaa tgtagccttt gttatattgg
    41161 caatcatact actgtctaag atgttcaatt ctgaggaaat actttttggt aatagtaaga
    41221 gtttctcttt cttagagaaa agaagtaata taaaaaaagg gtctatacca actgtaagtg
    41281 atggtgttat tttatatgca gtaggattaa ttctattgat ttatgttggt tctttagttc
    41341 aaattaaatt tggtatggca ggtattataa tgacacaatt catgataatt tctttaccat
    41401 tattatttgc atactatatt aaagctgatt ttaaagaggt atttagcttg acagttccta
    41461 aattaaagca tgtgtttggg agcattgttc tttggattgg tggatacata cttattatga
    41521 ttataacaca gctaatttta ttcttatttc ctcaaaatat ggaagttgct gaaagtttaa
    41581 ataaggctct ttttatcaaa gatagtgttt tactgaattt actagcaata gctttattac
    41641 cagctatatg tgaagaaatg ttttttaggg gatttatatt ttcttcattt agtaaatcaa
    41701 aagataaaaa taagtctatc aagctagcta taatatgcag tggggtacta tttggtatta
    41761 tgcatatgga ttttattaga ataattccaa catcaatatt aggtattata tttgcatata
    41821 gtgtgtataa atctggttca atatttgtat caatattatt gcatttttta aataatagtg
    41881 tagcagttgt gttaaatcat tatacaactg gaaatataac caacttatat aaatttgttg
    41941 aagttgattt ttcgaactta aatgtactta aatttgcctt aattcttcta ataagtctta
    42001 tattaattat gttaggatta agagttttag atagaaagtc tttaagaaat taagtataaa
    42061 gttattatat agattaaaat attaataagc actaaagtat atggatatat cttgtatata
    42121 aaaatacttt agtgctattt tatatatttt aattatatga attatttatc gtttcattta
    42181 tgtaatgaaa atgttatata aatgaaacaa taaataattt ttattttag
//
LOCUS       DAMJXI010000031        41253 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.033, whole genome shotgun sequence.
ACCESSION   DAMJXI010000031 DAMJXI010000000
VERSION     DAMJXI010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41253
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.033"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            368..2602
                     /locus_tag="PC465_002096"
     CDS             368..2602
                     /locus_tag="PC465_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2649390.1"
                     /translation="MQNHNYIKMLNKKVEVLSKELDSRNFKLKTLNEIDFFSKIPNRE
                     FMYQHIDDCISKNIHIGIMLLNIDNFKLFNDIYGYLVGENLLITLTQNLLHFIPESKG
                     IVAYLKGEGFLIVLPNVSNKELNNMGATIIESARELKIKLPNEKEIYSNVTFSIGSTI
                     WNGEPNMTTLMLFNQVYSALKKAKSEGKNRYILFDFKDNSFYNKLENDKEFLSEISHV
                     LQTKQIEVFYQPLYNIKNNTIVGCEALARWRHPIKGLLTPDKFIPLFEQFGLITELDL
                     HLFEENCKNIRRWIDNNDVFVPICCNFSRLHFFNPNFPSMLKGITEKYSVSTSNFSIE
                     ITENILIENTNTIIQQLAELRSYGFSVSMDDFGSGYSSFGMLQNLPFDIIKIDRIFLS
                     HNLNDFKNTTILYSIINIARALGMLTVCEGVETEQHVEFIKSINCDIAQGYYYAKPME
                     CKEFEKLLSKENNSKKMFIKYSDIGKSLIEKIFDGFFIMQDMKKLRANVTEDIQWFDF
                     YNKTEITSFPKVIEHFEKHIKGKKFSILYKSITPHNTESDSLLISGEAVLSDEASEHQ
                     KYSNFYFSANCIISENKLLLAKLHLDLIKTAGYINEFESYSIPKMTNTHLDESNILSQ
                     FYSMLPVGIIRYDLFGDMIITYMNEEMFDIIGYTKEQFFGEMGGNLRAIVHPDDLDFV
                     YKKSLDMIDTNKIEPFLYRFIKRDGQIVTVMYTQCNLSAIDGRSIAQGMYVDVNKIKN
                     LTKI"
     gene            2633..3478
                     /locus_tag="PC465_002097"
     CDS             2633..3478
                     /locus_tag="PC465_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2649391.1"
                     /translation="MFKEIFLRTFPGFLIIRDSNYRIIFINDNLKNLIKSYMQDNPLG
                     MTNIEIAKKLPDNIAKFFTDSHNIQLDWEKNYPYDKISNWILEFKKDTTSYWNVLEYK
                     VDVDEKTYIITMANDITKLYEENKRNLHYSITDPLTGAYNRKYLNDRFDIFIGDYIVL
                     IDLDNFKMINDYEGHNVGDKILCDFVSLLNKELINSTSIIRLGGDEFIVIFSSDVDKN
                     YVYSQLEALRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKEKNKKKF
                     DKNDY"
     gene            3718..5451
                     /locus_tag="PC465_002098"
     CDS             3718..5451
                     /locus_tag="PC465_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2649392.1"
                     /translation="MSILLKKAPKLAKHIITSFYINRDIDEVLKYLCENVTWIGPGEQ
                     EFLTSFNEIKNYFYAGQDEIPSCDINNDIFETVSEDENRCMVLGRYTVRTKENAQMIL
                     EVNQRCTFEIIEDRGKLLIKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTE
                     VIEMITNNINGGLKGSNDDSTYSFFYVNEGLPKILGYTYDEFMEMSGGSAVGAVYPPD
                     LPKALEDCERCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDIT
                     QLKNIESELKLERERYRIALQNITDIMFEYDIENDTLIKYQRVEIDKKIELENFETKN
                     YSKLLESGKIIHLDDIGKLLEVLHGNLRETIEIRQVNSLTKNEWRWIRVQCSVIYDSD
                     HNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIEEYLCSSDSKNND
                     ALLVIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTHDKDIVARIGGDEFTIFIKSL
                     TKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSK
                     ADGKNCYSTYE"
     repeat_region   5843..6726
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=5843..5871
                     /rpt_unit_seq="atttacataccacttagttaatataaaac"
     gene            complement(7256..7360)
                     /locus_tag="PC465_002099"
     CDS             complement(7256..7360)
                     /locus_tag="PC465_002099"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDF2649393.1"
                     /translation="MDDYIYYYNNFRYQNRLNSMSPFEFRKYLSTERA"
     gene            7985..8230
                     /locus_tag="PC465_002100"
     CDS             7985..8230
                     /locus_tag="PC465_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649394.1"
                     /translation="MNQKKIKISIKMVIIGIFAVIISFVLSRLFVEYIDELLRSNWQY
                     QLFESESSYIIFANCIMFSNILLEIFLIYICRKFRKI"
     gene            complement(8983..9129)
                     /locus_tag="PC465_002101"
     CDS             complement(8983..9129)
                     /locus_tag="PC465_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649395.1"
                     /translation="MVFETFDKAIELYPNAKPIFHSDIGFRLDDESFEEYLGRVFRKR
                     CKGI"
     gene            9162..9506
                     /locus_tag="PC465_002102"
     CDS             9162..9506
                     /locus_tag="PC465_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649396.1"
                     /translation="MNNNKFVAPNNVTLVERCYRYIKDRECSFSPNTIRNRKNMIKNQ
                     IEVFFKDMKLIDITPSILQSYINNIYNEHMLNSTKNQVDFIKLVLKESYRLKEISENI
                     CDFVTTPIKKIV"
     gene            10415..11770
                     /locus_tag="PC465_002103"
     CDS             10415..11770
                     /locus_tag="PC465_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2649397.1"
                     /translation="MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSK
                     GVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSI
                     IILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKT
                     DGFPILATVGVIISALTNIILDYLFVIEFGWGVKGAGIATGLSQVFSTIFFLIHFLRK
                     NSTLNFSKFRIDFKTLRKIVFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSV
                     INYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFVICM
                     AFSGPIVSLFIHPEETMLFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVI
                     SLGRGLVIVVLSLISMILIFGGQGIWMTTIVSEFICLILSLAFLKKNFSTLDSNLNKV
                     A"
     gene            complement(11888..12556)
                     /locus_tag="PC465_002104"
     CDS             complement(11888..12556)
                     /locus_tag="PC465_002104"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HDF2649398.1"
                     /translation="MKEVLKLADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTIS
                     EEHGKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFERALIKAKNMGATICAY
                     GDIDIESHRKWDTDRCEAVGMKVDLPLWQESREDLVYEFIDSGFCSVVTKVNLKHLGE
                     EFLGKKLTRELVENIKNAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKGTLIKDGYGY
                     LEIK"
     gene            complement(12623..13051)
                     /locus_tag="PC465_002105"
     CDS             complement(12623..13051)
                     /locus_tag="PC465_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDF2649399.1"
                     /translation="MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVG
                     AIFFLASIIVTGDLKCLVSINGFNYKLLLGGVFGGLIIYFTVKAIPNLGVSNTLILTL
                     VSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN"
     gene            13158..13751
                     /locus_tag="PC465_002106"
     CDS             13158..13751
                     /locus_tag="PC465_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HDF2649400.1"
                     /translation="MNFCYNCSIDFGGDFMYTNFNIDFNNFNKKENAIKFMLMGVLLI
                     ILGLLCLTFKTLGIKLISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWVL
                     IIACILLFVFPQKIQSIFSLFLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGIC
                     LILSPLFLSRFIVSIMSFFIILFGLVLFFSGNTARKY"
     gene            13870..14805
                     /locus_tag="PC465_002107"
     CDS             13870..14805
                     /locus_tag="PC465_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893027.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HDF2649401.1"
                     /translation="MDKFKYAFDNKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDG
                     SLGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYA
                     PLEVLKEKYETILELEDVIGLSISTRPDCLPDDVVEYLSELNKRTNLWVELGLQTIHD
                     STSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMVETAKAVGKMGVD
                     GIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKR
                     DELVGPIWSLKKWEILNQIDDTLKARNSYQGCKFV"
     gene            complement(15076..16020)
                     /locus_tag="PC465_002108"
     CDS             complement(15076..16020)
                     /locus_tag="PC465_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HDF2649402.1"
                     /translation="MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLTSEQVAFTRLF
                     FGFIVLGVYSSIRTPQILKISKKGIIYSVIIGIICQAMFNLCYFKAIDIAGVSIAAVL
                     LYTSPLFLAIFSKICYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGV
                     LSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSRPWEILNYAKDLDVLSC
                     MLMLGIVPAALAYIFYAAGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLF
                     GVMLMLISAVVALNLSYDEIRIFYKSNKLKQIEKTESI"
     gene            16338..17768
                     /locus_tag="PC465_002109"
     CDS             16338..17768
                     /locus_tag="PC465_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2649403.1"
                     /translation="MNLDLEFYQKILEASHDEICVSDDKGIIIYCNKAFEENYGLKKE
                     DILGKNVSFLEDSGYSTKSPIPIVLKTKTKFSLEQDTQTGKKLIITATPIFDENGNLE
                     FTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVMRPII
                     NTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRSNGPFITINCATISPQLLESEL
                     FGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFTPVGS
                     LKNKKVDIRIISATNVDLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVEIIKY
                     YFNRYSSDFNLNKTISKEAMDAIANYRFPGNIRELQNIIQKILLTCTDNHITIDDLPN
                     ILTKNIHITNNGNKTHISQINKVIISDSKSTNYKNKNFDTLIKEYEKNIILDAYEKFG
                     SSYKVAKHLEISQSKANRLIRKYTNT"
     gene            17968..18552
                     /locus_tag="PC465_002110"
     CDS             17968..18552
                     /locus_tag="PC465_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="HDF2649404.1"
                     /translation="MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYK
                     LKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSE
                     RWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMN
                     DLKFSAYTCNSVINYILDSILSNTIKSYHIANCG"
     gene            complement(18656..19435)
                     /locus_tag="PC465_002111"
     CDS             complement(18656..19435)
                     /locus_tag="PC465_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2649405.1"
                     /translation="MIKHIFCDLDGTLYENGTITKEDIVAIEEIEKKGVQFNVATGRI
                     FKQAHNIIKDSLDMNGYYVCENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQL
                     YFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIEL
                     YLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDIC
                     MLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS"
     gene            complement(19493..20749)
                     /locus_tag="PC465_002112"
     CDS             complement(19493..20749)
                     /locus_tag="PC465_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011591286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HDF2649406.1"
                     /translation="MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGD
                     NKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESF
                     FVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMF
                     NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTI
                     RITAKAENEREAFKLIKPVEEKIKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKN
                     LTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRLGVKRETLEEFGAVS
                     EQTAIEMAEGVAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVKKNIF
                     NGDRRKIRLRATRDLLNELRIQLEKL"
     gene            21007..21906
                     /locus_tag="PC465_002113"
     CDS             21007..21906
                     /locus_tag="PC465_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HDF2649407.1"
                     /translation="MKIAVIMGGISSEREVSLNSGKEIYNNLDKNKYEVVKVIIDDKK
                     DIFTKIPEDIDFAILALHGKFGEDGCIQSILETMDIPYSGCGPLCSGMCMDKNITKKM
                     LRDSNLPTAPWVLVKSVDEIDYDEIDNIGYPVFIKPNSGGSSVATFFIHSKDEVEEAV
                     RKGLEVDEFVMIEKYIPGGEYTSFILNGEVFPTISIKSDSGFFDYEAKYSVEKGAKEE
                     VVYLDEELQKRVNEISETCWKIFNCKAYVRVDMIISEGIPYVLELNTLPGMTQTSLIP
                     RSAAARGIKYSELLDKLIEYSLN"
     gene            21930..23378
                     /gene="ddlR"
                     /locus_tag="PC465_002114"
     CDS             21930..23378
                     /gene="ddlR"
                     /locus_tag="PC465_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DdlR"
                     /protein_id="HDF2649408.1"
                     /translation="MIFSNLKLNDNEPIYIQLKNYISDMISKGLIPDNSKLPSTRELS
                     QLLQVSRNSVVLTYEELKSEGLIYSISGKGTFVKSKNKSSNTTWSLNWDCLENTYSKK
                     ANELDIIKSEIPWSSDLISFKSISPDGDLFDMEELKKSFLNRISLEGHKLLNYGYAQG
                     YKPLIDYLLEYMTNKGADISNKDILITNGFTEGFDIIMSSFTQEKDYIICENPTHNTA
                     IKIMKSHNLNILGVDINEDGLDFNMLEDNLVKYKNKIKFAYITPSYHNPTGIVMTPEN
                     RYKFYNLMKKYNIATIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGM
                     RIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKF
                     NFAYKCIKKYIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNS
                     GFDTLRLGFSRLSFEDIEIGIKIIGETINEMF"
     gene            23437..24243
                     /locus_tag="PC465_002115"
     CDS             23437..24243
                     /locus_tag="PC465_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2649409.1"
                     /translation="MNLILGDNMSKKSKRRKINKLKLTIVITVLFLALLSIYEILFSN
                     PNKKGNIKSQETMQNKNNTTDDSKNNQSSTKKQEDNNIKPTFSYSSIPDNIKNKMIGK
                     SMPTDEPISFDSLSYLKLTYYGFDEKTHQGEMIVNSELAPEVVDIFKELYEKKYPIEK
                     IKLIDDYDAVDEKSMSDNNTSSFCYRTIAGTNVVSNHGKGRAIDINPLQNPQVSGNDV
                     TPKVSTVYADRSSTKFGMIKKGDDCYNAFVSRGWSWGGYWKNPDYQHFEK"
     gene            24269..26188
                     /locus_tag="PC465_002116"
     CDS             24269..26188
                     /locus_tag="PC465_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_071223118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2649410.1"
                     /translation="MNLMTLENISKSYSEKKLLENISLGINEGEKIGLIGVNGTGKST
                     LLKIIAGVEESETGNITKTNGIRIEYLPQNPTYNENSTVLEQVFNGTSEELKLLGEYQ
                     EILEKLNSNFTEELNKKLLSVHEKIDALNLWDLESEAKSVLTKLGINDFNQKIAELSG
                     GQRKRVSLASALITPCEFLILDEPTNHLDNDTIDWLEEYLNSRKGSLLMITHDRYFLD
                     RVTNRIIELDKGRLFSYDGNYSIFLEKKMERLSLEASIEDKRQNLIRTELAWVRRGAQ
                     ARSTKQKARLQRFDELINRDSFKPDENLDISVASSRLGNKIIEIHNISKSFEENTVID
                     NLEYTLTRTDRIGIIGKNGMGKSTLINILNGEIEPDSGYISIGETVKIGCFSQDDSHM
                     NIDMRAIDYVKEASDYIETSDGTRITASQMCERFLFNGTMQYTLIGKLSGGERRRLHL
                     LKILMTAPNVLLLDEPTNDLDIETLKILEEYLDEFKGVVVTVSHDRYFLDRICNKIFA
                     YEGNGKIHIYTGNYSDYLIYREIQGIEFEESKRESVKKDDSTTLKKEKPKNDKKLKFS
                     YNEQREFENIDSDIEKLESKIATLDESTAKFSTDFTKLQEILDEKSKLEKELEYKYER
                     WEYLNNLADEIANNK"
     gene            complement(26430..26777)
                     /locus_tag="PC465_002117"
     CDS             complement(26430..26777)
                     /locus_tag="PC465_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HDF2649411.1"
                     /translation="MSKSNDVLDIVFKITDGLEYEVAENSVVTILEKQDHKIQKFFRK
                     LKARIPKYKKIELDEYSSFVFLQIDGQRTVREIGKNLEAKYGEESHPLYERLLVFLNH
                     IEVNCHYIERLDI"
     gene            complement(26764..28692)
                     /locus_tag="PC465_002118"
     CDS             complement(26764..28692)
                     /locus_tag="PC465_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide transporter, OPT family"
                     /protein_id="HDF2649412.1"
                     /translation="MNKKLPKGAYGEVSGKDYVPYITDKSRTGGNVAVLIIGIILAAI
                     FAASTTYSGMKAGLTVAAGIPGAIIGSAFVGAFARSKGILGKNLIQGMSSGGESVASG
                     FIFVLPAVILIGSQITFLEGLAVGVGGVLFGIGIAAIVHNYLIVEEHGKLMYPESMAI
                     SETLVASEAGGDSIKYMGIGFVISGFITVLTGSFLNVANNVMSLVGSKFYKWKFDIEV
                     NPLLLGIGFIVGLEVSLTMFAGSILSNFGIAPLIGYFTDMAKDGAMVWNNPAMPLNQM
                     DVGAISSSYVKYIGAGMMLCGGIIGAIKLIPTIIASIKETLKAKSSAGEGEEGSSIQM
                     ILLLGGVVIGFLAAFLISGNIVMAIIGAIISLLLSLLFVIVAGRLTGTIGTSNLPVSG
                     MTIASLVIVTLVFVIMGWTDLEANKSLLLFGSFIVVAIAIAGGYTQSQKVTYIIGGSK
                     NEMQRYFTIASIVGVIVVVGVILLLSDQLRATGDNVQFALPQANLMSTLTSGIMSGSL
                     PWVMIIVGVFMAIVLYALNLPIMTIAIGFYLPIATTSIILVGALIRLFVELVSKTEKE
                     KEVKVSNGISLSSGLVAGGSIIGLIGIILQVTGVVTPKVPSGFAATNSMAIALLVVLV
                     VLTALPIVLSKVKNNEQE"
     gene            complement(29103..31292)
                     /locus_tag="PC465_002119"
     CDS             complement(29103..31292)
                     /locus_tag="PC465_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HDF2649413.1"
                     /translation="MYEVNLERAMNYWMDLLDDYTNIAKIPNDFFYKDCSDEVVDEVF
                     KMNIEKHERLIQYSKVNNISIDSIIETIYGLILQKYIYEDDVVFGKTMNIIPIRVRVR
                     QSEKFIDVVRKLKRQWSRSLEYGYYLLSDIENKNHLNTKLINTIFIAKSFDLSYDYDI
                     EKKGYDLSVIVYTKRALKIKIKYKPSIYKRETIRRILNQFDYIIEQIIEDNDILIEDL
                     EFVCKEEEKVLLEDFNNNQYEVPYDKSYVDLFREQVKVTPSNIAARDENRKLTYKELD
                     EVTDKLAGYLNHIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLN
                     YLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKLGYELTEKITSSNCAYTIST
                     SGSTGRPKTIAIEHKSLVNMCYYSVKSISATENDICGIYLSFSFDAVMKQLFPYLLVG
                     ASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERL
                     KGYRKRNYELYNEYGPTEFTVVSTSFHVDREYGKIPIGKPIFNTYAYVLDKKNKLCPI
                     GAPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEHNKLMYRTGDLVRWLDDGNLD
                     YIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCISRTNDDGDMYICAYYVIDEED
                     SGKINERTIREYLNEHLPPYMIPTIIMRIYKIPVTPIGKVNKRALPE"
     gene            31623..32354
                     /locus_tag="PC465_002120"
     CDS             31623..32354
                     /locus_tag="PC465_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDF2649414.1"
                     /translation="MNIYAHRGFSGKYPENTILAFKKCLDMDIYGIELDVHRTKDGKI
                     VVIHDEKVDRTFNGHGFVKDFTLRKLKTLNSSFEGYQSNKECKIPTLEEVLILISPTD
                     LILNIELKTDKINYPNIEKDVLELILKYNMKNRVLISSFNSNSLKNFHKLDPSIKTGL
                     LCYLPINNVVNFAKFLGNSYLHPPLVLVNESLIELCHKNLLGVNVYTVNEEDDILHCL
                     KLNVDGIFTNYPDIASNLLHSKQYS"
     gene            32434..33069
                     /locus_tag="PC465_002121"
     CDS             32434..33069
                     /locus_tag="PC465_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDF2649415.1"
                     /translation="MDNLLNELEALKSNLDNLPIEKIENYDLSKTALFIIDVNNGFAR
                     QGALYSPRVESLIKPIEMFTKKISNKLNRVIAFTDSHTPKSIELLSYPVHCLENDVES
                     ELVDELKSIENLQILPKNSTNGFFALENLDFDNIDNIIIVGDCTDICIYQFAITLKSY
                     FNQHNIEKNIVVPMNLVDTYDIPNVHPAEILNLVFFNSMIQNGVNVLKEIR"
     gene            complement(33320..33913)
                     /locus_tag="PC465_002122"
     CDS             complement(33320..33913)
                     /locus_tag="PC465_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3867 domain-containing protein"
                     /protein_id="HDF2649416.1"
                     /translation="MSDDRIIDFNELKNKVKDSDVDKFEQYIYNLYFSVMDGKMSMAE
                     FSRKIFDYMRDNNISQEKFMKIQKQFMERYGMDTEEVEKQLRNFGIDPSTAGFMSNNT
                     SSKVSTEDLESFKKSAGFYEKYGEKIQPKSCITTFIKNDLNDINVIIDQEKIMLCSDR
                     KINLMDSELNEFLLEYKNMFNKKIKVVMCETTNKYDY"
     gene            complement(33984..34847)
                     /locus_tag="PC465_002123"
     CDS             complement(33984..34847)
                     /locus_tag="PC465_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HDF2649417.1"
                     /translation="MLGIIAPSGPLRNTSLEEIKFNLESYGYEVKFSESCSLNYKGYL
                     AGNDDIRARDIEDMFLDKDVDIIMCLRGGYGTTRILDKINYDIIKQNPKPFIGFSDIT
                     GLNLAFYKNCGLLPYHGIMAANVGKWDKFTYKSLVNALEFKDELYLENPKEEKIYTVC
                     EGKAEGIIMGGNLSLIIATMGTKYEIDAKDKILFIEEIGEPQYKLDRMLTQLYSSGKL
                     EECNGIIFGDFKDCIEENDLMELLIEFANKVNKPSIYNLQSGHCIPMITIPLGRMCEL
                     DATEKIVKLKK"
     gene            35010..36179
                     /locus_tag="PC465_002124"
     CDS             35010..36179
                     /locus_tag="PC465_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2649418.1"
                     /translation="MLNIKTLCHEINDWVINIRRDLHKTPELGLEEFQTKKKIIKYLN
                     EIGINYIEYKNHTGITAYINVSPNFETVAIRADIDALPITEELNYSYKSINIGKMHAC
                     GHDAHTAILLGTCNILFKLKDYLNVNVKFFFQPAEETIGGAQLMIEDGCLENPNVKYI
                     FGLHVNPNINKNLIELKYNTLNASTDTLQLTVHGSKCHGAYPHQGIDAIVISAHIITA
                     LQTIVSRNTNPTDSVVISLGKIEGGIKENIVCDKVVIRGTLRTLTPETREFSKKRIRE
                     ICDFTCKTFGGSISVEIEEGYPALINSNHLVDYVKQNAVELFGEENIILKDSPTLGAE
                     DFSYFLRHCEGAFYHLGCANREKNITSPLHTSTFDIDEDCLITGVMLHVKNVLSF"
     gene            36280..36756
                     /locus_tag="PC465_002125"
     CDS             36280..36756
                     /locus_tag="PC465_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDF2649419.1"
                     /translation="MKEILINPIGKICIQGEEVFIKLDKKYVPALNELDDFSHLNVFW
                     WADGFDNPELRSILETPKPYKSGPDVIGIFATRSPIRPNPIALTAVQIINIDHENGII
                     KIPYIDANDNSPVIDLKPYTPSVDRVENPSVPKWCSHWPKSVEKSGEFNWEDEIEF"
     gene            37322..38116
                     /locus_tag="PC465_002126"
     CDS             37322..38116
                     /locus_tag="PC465_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M55 family metallopeptidase"
                     /protein_id="HDF2649420.1"
                     /translation="MKLYLSADIEGTCGIVNWDETKLECEFSQHYRTQMSKEITAACD
                     GATQSGVHEILVKDAHDSGRNINPNILPENVKILRGWTKDPLVMMAGIDESFDACIFT
                     GYHSGATCNGNPLSHTMDIDYDYFKINDEIASEFTINAYIAAYYNVPVAFLSGDEMLC
                     ESAKKLNPNIVTVPVSKGIGNGSISIHPNLALKKIEKGVKKALSGDLSRHLIKLPDKF
                     KIEIKFREHYKAFKASFYPNMKKIDSQTVLFETEDYYEFLRMLLFI"
     gene            38140..38583
                     /locus_tag="PC465_002127"
     CDS             38140..38583
                     /locus_tag="PC465_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory YrvL family protein"
                     /protein_id="HDF2649421.1"
                     /translation="MIKISNKRRIPLGEFISVFLFFAVFFGITFCIFTVIGIGFLSFL
                     GFEYKSLGAVLIFFLIYFCITTPIDFLCTTILDIFRYVNKLPYSIYKLCEFIIDFILT
                     FLAMNIIDTFMDSVTIPLSTEILFALLSYLLSECMDFFDRDKKKP"
     gene            complement(38672..39958)
                     /locus_tag="PC465_002128"
     CDS             complement(38672..39958)
                     /locus_tag="PC465_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDF2649422.1"
                     /translation="MEKVKVAVIGAGNRGTYAYAPYIYENSDVCEIVAVAEPKKGRRE
                     LFTKKYNLDSKNVFETLEDFFKHDKMADAVIIATNDDRHYDVAKLALEKGYHVLLEKP
                     MSNSLDGLVHIDDLCDKYKDKIFMICHVLRYSPFYNKLKEIVESKKLGELVSIQYNEN
                     IGYWHFAHSFTRGNWRNSNETSPLILAKSCHDMDILLYLVGSRCKKISAFGSLKHLNN
                     QNASGEMAQNCLQCLVEKKCPYSAKRIYLEKDRSINRAVHINPTEENLLNILKTSPYG
                     RCVYRCDNNVVDNMVNILQFENGVTATFNLCAFTKENGRTIKLMFSHGEVGGDLNKNE
                     IRIKEFGKNEEIVMNPSNQQNMVEEYDRNLIAEFIKLVSNKELEKGRVAAKEAIQSHV
                     MAFAAEYSRVSDEVVYIEEFFDSAKQMTKEIEETIF"
     gene            complement(40176..41066)
                     /locus_tag="PC465_002129"
     CDS             complement(40176..41066)
                     /locus_tag="PC465_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDF2649423.1"
                     /translation="MSSTIKSNRIKGIMFIIASALGFAMMSAFVKLAGDLPSFQKVFF
                     RNLVSAIIAFWLIIKHKGSLTGKKENLKVLLYRSIFGTLGVIFNYYAIDKLMLSDANM
                     LNKMSPFLVVIFCAIALKEKINVKQIGAIIIAFIGALFIIKPTFSVEVIPYLGGIAGA
                     VFAAMAYTCLRVLGDREDYYTIVFFFSVFSLVTVGPIAFAVYEPMTLMQLIYLLLGGV
                     FASLGQFGITLAYKYAPAKEISIFDYSNIIFSAILSIFLFNVYPDMLSVVGYLIVFSA
                     AFYMFLYNKKLDKLDKEKKK"
BASE COUNT        15266 a         5892 c         5174 g        14921 t
ORIGIN      
        1 gttaattatg aataaaataa ttatgccttt gaaaaatcat taaacttaaa attaattata
       61 aaaaaactct accttactaa ctatacagct cacaatctat ctatttatga aaaaatatga
      121 tataattgca ttcaaaaagg aaatctttca atatactaga atttaagcat taactaattt
      181 tatctaatat tattactaaa ctaaaaaata tttgtatttg tagcattgga gcaagtaact
      241 taatgtatat tcattttaaa tacttattta aaatttagca tttaaattat ttacaaatta
      301 acatttaaat acttctagca taaatacagt tgtcatcaaa atttaaagta tcttatggag
      361 gaataccatg caaaatcata attatataaa aatgttaaat aaaaaggtag aagtattatc
      421 taaggaatta gatagtagaa attttaaatt aaaaacctta aatgaaatag attttttttc
      481 taaaatacca aacagagaat ttatgtacca acatattgat gactgtattt cgaaaaatat
      541 acatatagga atcatgttat taaatatcga taactttaaa ttatttaatg atatatatgg
      601 atatctagtc ggagaaaatt tattaattac tctaactcaa aacctattgc actttattcc
      661 agaatcaaag ggaatagtcg cttatttaaa aggagaaggt tttttaattg tacttccaaa
      721 tgtatcaaat aaagagttaa ataatatggg tgcaactatt atagagagcg cccgagaatt
      781 aaaaataaaa cttcctaatg aaaaagaaat atactccaat gttacattta gtatcggcag
      841 cactatctgg aatggtgaac caaacatgac tactttgatg cttttcaacc aagtatatag
      901 tgctttaaaa aaggctaaaa gtgaaggcaa aaatagatac attctatttg attttaaaga
      961 taatagtttt tacaataaat tagaaaatga taaggagttc ttatcagaaa tatcacatgt
     1021 tctacaaact aaacaaattg aagtatttta ccaaccactt tataatataa aaaataatac
     1081 tatagttgga tgtgaggcac ttgcaagatg gagacaccct attaaaggac ttcttactcc
     1141 agataaattt attcctttat ttgaacagtt tggtctgata acggaattag atttgcattt
     1201 atttgaagag aactgtaaaa atataagaag atggattgat aacaatgatg tttttgttcc
     1261 aatttgttgt aacttttctc gtcttcattt ttttaaccct aattttccaa gtatgctaaa
     1321 aggtattact gaaaagtaca gcgtctctac atcaaatttt agcattgaaa taacagaaaa
     1381 tatattaata gaaaatacaa atacaattat tcaacaacta gctgaacttc gttcttatgg
     1441 tttttctgta tcaatggacg attttggttc tggatattca tcttttggta tgttgcaaaa
     1501 tctacctttt gatataatca aaattgatag gatattttta tctcataatt taaatgattt
     1561 taaaaataca accattttgt actctataat aaacattgca agagctcttg ggatgcttac
     1621 agtatgtgaa ggtgttgaaa cagaacaaca tgtagaattt attaaaagta taaattgcga
     1681 tatcgcccaa ggttattatt atgcaaaacc catggagtgc aaagaatttg aaaaattact
     1741 atctaaagag aataattcaa agaaaatgtt tataaaatat tctgatatag gaaaatcttt
     1801 aatagagaag atatttgatg gattttttat tatgcaagat atgaaaaaac taagagctaa
     1861 tgtcactgaa gacattcaat ggtttgattt ttacaacaaa actgaaatta catcttttcc
     1921 taaagtaata gaacattttg aaaaacatat taaaggtaaa aaattttcta ttctttacaa
     1981 aagtataacc ccacataata ctgaatcaga ttcattatta attagtggag aagccgtttt
     2041 atcagatgaa gcttctgaac atcaaaaata tagcaatttc tactttagtg caaattgtat
     2101 aatttcagaa aataaattac tcttagcaaa attacatttg gatttaatta aaactgctgg
     2161 ctatataaat gaatttgaat catattcaat acctaaaatg acaaatacac atcttgatga
     2221 aagtaatatt ttatcacaat tttattcaat gttgcctgta ggtataattc gctacgattt
     2281 atttggtgat atgattatta cttatatgaa tgaagaaatg tttgatatta taggttatac
     2341 aaaagaacag ttttttggtg agatgggcgg aaatttaaga gcaattgttc atccagatga
     2401 tttagacttt gtttataaaa aaagtttgga tatgattgac acaaataaaa ttgaaccatt
     2461 tttatataga ttcataaaac gagatggtca aattgtcaca gttatgtata cacaatgtaa
     2521 cctttctgca attgatggaa ggtcgattgc ccagggtatg tatgtagatg taaataaaat
     2581 aaaaaattta acaaaaatct agtacaaagt attttatttt ggagaaatta atatgtttaa
     2641 agaaattttt ttaagaactt ttccaggatt tctaattata agagattcta actacagaat
     2701 tatatttata aatgataatt taaaaaattt aattaaaagt tatatgcaag ataatccact
     2761 tggaatgact aatatagaaa tagctaagaa actccctgat aatattgcta aattttttac
     2821 ggattctcac aatattcaat tagattggga aaaaaattat ccttatgata aaatttcaaa
     2881 ttggatttta gagtttaaaa aagatactac aagctattgg aatgttttag aatataaagt
     2941 agatgttgat gaaaaaacct acataattac tatggccaat gatataacaa aactctatga
     3001 agaaaataag agaaatcttc actactcaat tactgaccca ttaactggag catataatag
     3061 aaaatattta aatgatagat ttgacatatt tataggagat tatattgtac taattgactt
     3121 agataatttc aaaatgataa atgactatga aggtcataat gtaggagaca agattttatg
     3181 tgattttgtt tcacttttaa ataaagaatt aataaattct acttctatta taagattagg
     3241 aggagatgaa tttattgtta tattctctag tgatgttgac aaaaattatg tttattcaca
     3301 gctagaagcc ttaagagaaa attttttaaa agtattctct aagtataagt atctttcatt
     3361 tagttatggt gttgatacag taaaaagaaa tttaaaattg acaatagttg aattggataa
     3421 aaaaatgtat aaaaacaagg agaaaaacaa gaaaaaattt gataaaaatg attattaata
     3481 ttgttatttt aaaataaatt aaaattatct ttcttttttt aaacttgtac attagtttat
     3541 aaatatgtat ctatacaaga tattgacatt aagtactgaa gcatatattg tttcagttct
     3601 tttttgttaa aattaactta tttgacaaag atatcatagt ttaacaaagc ttttaattta
     3661 aatatattga tgtataatat aattaaaata taatagcaaa aagaaaggag gaatatcatg
     3721 agcatactcc taaaaaaagc acccaaatta gcaaaacata ttataacaag tttttatata
     3781 aatcgggata ttgatgaagt attaaaatac ctttgtgaaa atgttacatg gattggacca
     3841 ggagaacagg aatttctcac ttcttttaat gaaataaaaa attattttta tgcaggtcaa
     3901 gatgaaattc cttcttgtga tataaataat gatatatttg aaactgtaag tgaagatgag
     3961 aatagatgta tggtattagg aagatatact gttcgaacta aagaaaatgc tcaaatgatt
     4021 ttagaggtaa atcaacgttg tacatttgag ataattgagg atagaggaaa attattaata
     4081 aagcacatgc acatatcaaa cccttatggt gaaatgcaac ttgatgaata ctttcccact
     4141 aaaattggaa ctcaaagtta tgattatttg caaagattac taaaagaaaa aacagaagtt
     4201 attgaaatga ttacaaataa tatcaatggt ggcttaaaag gtagcaatga tgatagtaca
     4261 tactcatttt tctatgtcaa tgagggattg cccaaaatat taggatacac atatgatgag
     4321 ttcatggaaa tgagtggtgg ttcagcagtg ggtgctgtat atccaccaga cttacctaaa
     4381 gcactagaag attgtgaacg atgttttgca aaaggaccta catattcatc tgaatataga
     4441 atccgaaaaa aagatggaac attaatgtgg gtattagatt ctggaatgaa atcgttaaat
     4501 agtgatggca tagtaaaaat taatagtatt attactgaca taacccaact aaaaaacata
     4561 gaatctgaac taaaattaga aagagagcga tatcgtattg ctttgcaaaa tattacagat
     4621 atcatgtttg agtatgatat tgaaaacgat acccttataa aatatcaacg tgtagaaatt
     4681 gacaaaaaaa ttgaattaga aaattttgaa acaaaaaatt actccaaact attagaatct
     4741 ggtaaaatta ttcaccttga tgatattgga aaactactag aagtacttca tggaaatctt
     4801 cgtgaaacaa ttgagataag acaagtaaat tcattaacta aaaatgaatg gagatggatt
     4861 cgtgttcaat gttcagttat atatgatagt gaccataacc ctatcaaaac aataggcgtt
     4921 ttaaaagaca taactgaaga taaatctaaa ttagaaagct taattaatca ggctcaacgt
     4981 gacccactaa cacaattata taatcaaaga gtatcacaaa atcttattga agagtatcta
     5041 tgtagttctg attccaaaaa taatgatgct ctattagtta ttgatattga tgattttaaa
     5101 actgtaaatg atacttttgg gcatttagag ggaaatgaag ttttagttgc tgtatcaaaa
     5161 atactattac ataacacaca tgataaagac atagttgctc gaattggtgg agatgaattt
     5221 acaatattta taaaatcatt aacaaaggat ttaataataa aaattactaa tgatatttta
     5281 aatgatgcaa gtaaaataaa agtaaaggac aatcataaaa taacattaag tattggtatt
     5341 gccttcactg atgattcaac taaattatat aaagatttat tttctaaagc tgataaagct
     5401 ctttatctat caaaagcaga tggcaaaaat tgttatagta catacgaata ataaagctat
     5461 ttatacgacc aagaatgaac ctttaaattt aatttcatag tctaacaatc aaagaattga
     5521 agctaatctt atagctagtc aactagttcc tagaaaaaat ttagacaata tatttattga
     5581 tactgctcat ttttctaaag agcaaattta tataaaaaat taaactttta tgtacataca
     5641 gatactaatg ataaacattt agcattagta tcttctatct taaaacaaaa tgataattta
     5701 tctatataaa aaagtgcttt gttgacagag ttcacttttt tatataggta cagaatttaa
     5761 gtataaatac atgttttatt ctatacattt tagttaatgt aaaattcctt gattgtactc
     5821 tctaactttt caacattata ctatttacat accacttagt taatataaaa ctataaaagt
     5881 gttgcaatta ctgggtttta taaagttaat ttacatacca cttagttaat ataaaacttt
     5941 agcaccttat ttatctatag agctacagaa agtatttaca taccacttag ttaatataaa
     6001 acaagcatca aatacattta tcattctgtc tataatttta tttacatacc acttagttaa
     6061 tataaaacta atacctcctt ttataaaaaa atgtcgtgaa aaagtattta cataccactt
     6121 agttaatata aaacatgtat ttatttgttc ttgtactatt gttttactct atttacatac
     6181 cacttagtta atataaaaca ctccaaaact tgattctaaa tttagaaaag gactatattt
     6241 acataccact tagttaatat aaaactgtag aaagctcgtt tgtggatgaa gttctaaaat
     6301 catttacata ccacttagtt aatataaaac ggaactttta aaagattcaa ggaaaaaaga
     6361 ttggtttatt tacataccac ttagttaata taaaacttgt aaggataagc ctagagagaa
     6421 tagcccttct ctctatttac ataccactta gttaatataa aacattattt ttttatcgtt
     6481 ttgaaacctg tttcttctgc atttacatac cacttagtta atataaaact atcttttgat
     6541 tattctgata aaaagtaata atacaaattt acataccact tagttaatat aaaacgctcc
     6601 cgaagttgtt aatgttgttg cgactcttgc tgatttacat accacttagt taatataaaa
     6661 catcaatact ttgatgcagt ttttaactag attttcaatt tacataccac ttagttaata
     6721 taaaacccca aaataaactg ggcattttca atacttacac atatgcaact ctcttaaatt
     6781 tgcagtgaac catgagtagt gcaaatgata aagcttatca tataccctca acaccttata
     6841 tttcaagcgt taagctctac tttgtaacaa atatcgctca ctgcaaaact atttacattt
     6901 ttattatatc ataaatatat tatttttgaa tatctatacc aatttgtggt ataataaaag
     6961 caagaagaac tacaatctat ttagacgtag agtgaagttc aaatactaat gtttattctt
     7021 tttgaacttg atttttagtt caaaactaaa gtcactcctg cctgtgtgaa ctatacccgc
     7081 tgttttatac agttaaaaca tgtaaaaata gttataaagt actagtgtaa ctcattagta
     7141 ctctttttat tatattcata taattaatat ctatatttta aagtttacta tctaaaaaag
     7201 agcacgtcaa ataaaaccct agatatttaa tttttttaga gatacttaaa ataaattatg
     7261 ctctctctgt acttaaatat ttcctaaatt caaatggaga catagaattt aatctatttt
     7321 gatatctaaa attattatag tagtatatat aatcatctat tgctttaact aattattcat
     7381 atgtatcaaa tttccttaaa tagtacattt ctacctttaa aattccccaa aatccttcca
     7441 taggagcatt gtcaaggcaa cgaccaactc ttgtataata tatgtatatc taacaccatt
     7501 aagaaatata tattttataa tatatatttc ttcatttaat gcacttagaa aagcaaagaa
     7561 aatacagatt agtacacttt ttagagaaaa ataaaattga tacatctaaa atattaaaaa
     7621 atactttaga taatctaaag acacatctca aagtttttaa ctaaattata aaactaatta
     7681 caaatgctat gtaacgataa taaataaaaa atttacttcg cttaagcgac gtgtcgttga
     7741 aatatttcat gttgccaact ggttcgtaag ttgataagaa aagaacacta attatttaga
     7801 gttcttttct tagctacaag tggattataa tacttttaaa tctgtgcgaa aattgtatat
     7861 aataatgata tgaacaagta aagaaaatac aaaaatgaca aaattataaa taaaatatta
     7921 taaaatcata aggtcataat tgttatattg tagaaacaaa gtaaagagag atggtggaga
     7981 ataaatgaat caaaaaaaaa taaagattag tattaaaatg gtaattatag gtatatttgc
     8041 tgtaattatt tcttttgtat tatccagatt attcgttgag tatattgatg aattattaag
     8101 gtctaattgg caatatcagc tatttgaaag tgagagttca tatataatat ttgccaattg
     8161 tattatgttc tcgaatatat tattagaaat atttttaata tatatttgta gaaaatttag
     8221 aaaaatctaa tatagtcaac gtatttcgaa tcgaatactt catgattatt tagtctattg
     8281 tgctagttaa agtttaattc ccatataaag taaattgatt ttagtaaaac aaatcacccc
     8341 taagggttag tttatggata agtcatccaa atattaactc tttaattttt gctatagatt
     8401 catctttgct cataacttta cttataaaaa atgaaatatt ataagctaga acttttattc
     8461 taattctagt cataaatcct agcatagagt tacttttttt atattataaa taaaactata
     8521 caacaaagat aatatttagt aaaaataact ttcattttaa ctaaacttaa aattcaatta
     8581 ctctctaaat tgacgtttag gaattagttc aaaataaaaa agagtgtata tattgaaatt
     8641 actacatttc aatatataca ctctttttaa atttctcagt tttccatgga actttacttt
     8701 atttatttct gtattagttg tattttttat gcatttttct ttaaaatcat attttctgat
     8761 tcaactctta tattataaaa tttctttact aaattattct ctttttctat atcttcatat
     8821 atatttttta atcgcctttt acctaatctt ttatctaaca ttactaatga tttaactaat
     8881 atattatatg attttatcgc atcttctact gagatattta aacatatatt tactgcttta
     8941 taaaaatcaa attcactaaa aaatccattt ttatttacaa tcttatatcc ctttgcatct
     9001 ctttctaaat actcttccta aatactcttc aaaactttca tcatctaatc taaatcctat
     9061 atcactatga aaaataggtt ttgcatttgg atatagttct attgctttat caaaagtttc
     9121 gaataccaag ttattattat tcgattttcc aatagcccac tataaacaat aataagtttg
     9181 ttgctccaaa taatgtaaca cttgtagaaa gatgttacag atatataaaa gatagagaat
     9241 gtagtttttc tcctaatact attagaaata gaaaaaatat gattaaaaat caaattgaag
     9301 ttttctttaa agatatgaaa ttaatagata taacaccttc tattttacag tcttatataa
     9361 ataacatata caatgagcac atgttaaatt caacaaaaaa ccaagtcgat tttataaaat
     9421 tagtattgaa agaatcttat agattaaaag aaatatcaga aaatatttgt gattttgtta
     9481 caaccccaat caaaaaaata gtttaacttc taagctttat acaaaacaaa aagctcaatt
     9541 attattagaa aaatcaaaaa atactcctat aggtatacca atttttttga tgctaactct
     9601 tggattacgt tttggtgaag ctgtatcact tatatggtca gatgtagacc ttgataaaaa
     9661 atctcacatg taaatcaaac attagtttat gtatacaata aaataatctt caaaggccct
     9721 aaaaccccta gattcaaaag aagattattt gttcctgatg aacttataag tttgcttaaa
     9781 ggggaaaaat taaaacaaaa taagttgaaa ttacagggta tattgaaaaa tgaatttgat
     9841 ttgatatgct tagataaaag attcaacccg tgagttcaac caacttttgt tgttcatttt
     9901 aaaaaactat taagagataa taatcctaga gatataaaag tacatgaatt aatacatgca
     9961 aatgcaactt tgatattact ttcaggtact aacataaaag ctatttataa aatattagta
    10021 catgcagata taaaaatagc tatgaataaa tattcgatat tctcacttat tagatgaaat
    10081 ggataaagaa acatctgaaa atataagcaa aatactattc aaataatgtt cagttttatg
    10141 tcaattaaat gtcactcaaa gtgctttttt tccatttgtc agttaaatgt cacttaaagt
    10201 acctttttcc tatttgtcag ttaaatgtca gtaatatata aataagatat atttataaga
    10261 cccttaaaat cactattatt taataaaatt tataattata tactatttgt tgttgacatt
    10321 ggtattatac catagtttat catttatatt agaaataaaa ttattaatta atagtttcgt
    10381 aattttataa tagatttaca gggagtgata ataaatggat acaaaaatat ctataaacga
    10441 aaacatgagt ctaggtaaaa gattttttaa atacctagca ccatctgtag ttgcaatgtg
    10501 ggttttctca ctatatacaa tggttgatgg aatatttgta agtaaaggag ttggagaatt
    10561 agctttagct gctgtcaata tatcaatgcc ttttattaat tttatatttg cagtttctct
    10621 attattttca actggtgcat ctaccataat tgcaatctat ctggggaaaa aagatattaa
    10681 atctgctaac gaagtctttt catttaactt agtatcaata attatattat caataattat
    10741 attagctata acttttttta atttagatag attagcacta tttttaggag ctacagaatc
    10801 tacaattggt atggttaaag attatttagg aataataata ttttttaacg gattctttat
    10861 agtgtcttat tctttagaag ttataataaa aactgatggc tttccaatat tagctactgt
    10921 tggtgtaata atatctgctc ttacaaacat catacttgat tacttgtttg taattgaatt
    10981 tggatggggt gtaaaaggtg ctggtattgc aactggtttg tctcaagtct tttctactat
    11041 tttcttctta atacattttt taagaaaaaa ctctactttg aatttttcaa aatttagaat
    11101 tgattttaag acacttagaa aaattgtatt tataggtttt cctgattcaa ctactgaatt
    11161 aagttgtggt atagttgttt tactttttaa cttaagtctt actaaatata ttggagaaaa
    11221 tgctcttatt tattatagtg tcataaatta tataaataca ttagtactta tgactatgat
    11281 gggtataact caaggtatgc aaccacttac tagcttttat tatggtgcag gaaatataga
    11341 taatgtaaaa aaattattaa aaatggggat aaaagccaca ataatagcat cagttgctgt
    11401 atttgtaatt tgtatggctt tttcaggacc aatagtctct ttatttatac atccagaaga
    11461 aacaatgcta ttcaatgaag gagttcgtgt atttaaaata ttctctatat ctttcttatt
    11521 ggtaggaatt aatgtaataa tttctggatt ctttgtatca gtagaaaaac catcaatttc
    11581 tactgttata tctcttggta gagggcttgt aatagttgtt ttaagtctaa tttcaatgat
    11641 actaatattt ggtggacaag gaatatggat gactactatt gtttctgagt ttatatgtct
    11701 tattttatca ttagcttttc taaaaaagaa tttttctaca ttagactcta atctaaataa
    11761 ggttgcttag atgataagag tgacaatata tgaaaatatc taaataaaaa atacctatta
    11821 tacaatctta caaatattag acctttgcaa aaattaggat tatataatag gtattttatt
    11881 tatgtaatta ttttatttct aaatatccat agccatcttt tattaaagtt ccttttactt
    11941 catattctac aggtttttta aatattggac catctacgac aaatgtatga tactctccat
    12001 gttctccaca tgggtctgca ccagcatttt ttatattctc cacaagttct ctagttaatt
    12061 tttttcctaa aaattcctct cctaagtgct ttaagtttac ttttgttaca acactacaaa
    12121 atccactgtc tataaattca tatactaaat cctctctact ctcttgccat aatggtaaat
    12181 ctactttcat accaactgct tcacatctat cagtatccca ttttctatga ctttctatat
    12241 ctatatctcc atatgcacat atcgttgctc ccatgttttt agcttttatt aaagccctct
    12301 caaagctctc ttcatatcct tctacgccac actcagcaac taataaaggt aatcctatgt
    12361 tgctacttac ttgcttaagc atattatatt ctaaattatg tgtccatgac tttccatgtt
    12421 cttcacttat agttgtcaag agtgccacag gcttatatcc ttttttcaac attcgattta
    12481 atgctaatat actatcctta ccaccactaa atgacattac aaatttttca tcagccaatt
    12541 ttaacacctc tttcatctaa ctttgtttta ttaacataat tataccaaat ttttgagttg
    12601 catagcaaat tatattaaat tgttaattca ctataaagaa tgtccctaat attaaaagta
    12661 taacccctat gtatttgtat aaatgcattg tttcttgtcc caaaattacg ctatcaataa
    12721 aaaatccaac taaaacttgg gatacaagag ttaatataag tgtatttgat actcctaaat
    12781 ttggaattgc ctttactgta aaatatatta ttagacctcc aaatactcct cctaataaca
    12841 acttataatt aaaaccattt atagatacta gacactttaa gtcacctgta actattatac
    12901 ttgccaaaaa aaatattgct cctacagtta agcttataaa ggtggccact aatgctgttg
    12961 tactttttcc tagctctcca tttataaaag cttcaagagc tgtagaacca cctgctaata
    13021 atgcaaatat tattgcccat aattttgtca tggacaaacc tccttctata taattctatt
    13081 aatagaagtt tatgatacaa cctattaatt aattactaag tatagtttaa tttttataca
    13141 ctaggcttta tttggatatg aatttctgtt ataattgttc tatcgatttt ggaggtgatt
    13201 ttatgtacac aaattttaat atcgatttta ataactttaa taaaaaagaa aatgctatta
    13261 aatttatgtt aatgggagta ttactcatta tattaggatt attatgcctt acatttaaga
    13321 cattaggtat aaaattaatt tcttggactt ttggtattgc acttttattc tttgcatatt
    13381 taaatttaaa aaatattaat gagttaaaaa gatatgctac taaagaagaa attaaaccct
    13441 ctattaatat ccaatgggtt ctaataattg catgtatatt actttttgta tttcctcaaa
    13501 aaatacaaag catattttca ttatttttag gattttattt aatctttaat caactagtag
    13561 cacttgtaaa tagtaagaat aatccttatt ctaaatttac aacttggaat atagttaaga
    13621 ttctatttgg tatatgcctt atattatctc cacttttttt atctagattt atagtatcga
    13681 taatgtcttt tttcataata ttatttggac tagttctatt tttctctgga aatacagcga
    13741 gaaaatatta attattttct cgctgtattt ttatattact taaaatagaa tttgtttaag
    13801 ttatctattt gtggtaatat gttttttgta caagctcagc gtacaatttt attagaaata
    13861 ggtgattttt tggataaatt taaatatgct tttgataata aaagatatca tacttggaat
    13921 tactatctta gaaatacttt tggagaaaaa gtttttaagg tatctataaa tgcaggattt
    13981 acttgcccaa acattgatgg aagtcttggt tatggcggat gtacctattg tagcaaagaa
    14041 ggctcaggtg attttgctgg aaaccctaaa gataatctta tcagtcaatt ttataatata
    14101 aaagaaatga tgttaaaaaa atggcctcat gcaaagtata ttggctactt tcaagcctat
    14161 acaaatacgt atgctcctct tgaagtttta aaagaaaaat atgagactat attagaactt
    14221 gaagatgtca taggtctttc aatatccaca agacctgact gtttgccaga tgatgttgta
    14281 gaatacttat ctgaactaaa taaaagaacc aatttatggg ttgaacttgg acttcaaaca
    14341 attcatgatt ctacatctaa aattataaat agaggtcatg attataaaac atttgttgaa
    14401 ggtgttgaaa aactaaagtc taaaaatata aaggttgtcg tacacattat aaatggtctt
    14461 cctggtgaag attataatat gatggtggaa acagcaaagg cagttggtaa aatgggtgta
    14521 gacggtataa aaatccatct attgcatgtt ataaaagata ctcctatgga aaagatgtta
    14581 caaaatggta tgttaactct tatggaacaa gatgaatata tcaatcttgt ctgtgaccaa
    14641 ttagaaatac ttcctgaaac tatgataatc catagactca ctggtgatgg taagagggat
    14701 gaactagtag gtcctatatg gagcctaaaa aaatgggaaa ttttaaatca aattgatgat
    14761 actttaaagg ctagaaattc ttatcagggc tgtaagtttg tttaatacaa aataataact
    14821 atagaaatgg ttatataaat atagtccttt ctatagttat ttagtattta caaaacaaaa
    14881 tattaatttg tacatttata caatatataa taaaaaatag atagtctaaa ctgtatctac
    14941 ttatatttta tttgtactgt ccactttatt ctataaaatt tataaatagt tattttttaa
    15001 taccaaatat aatttggtat aatttttgtt ggactctaaa atgtatacca ataaatcctt
    15061 tttaagtata taattctaaa tactttcagt tttttcaatc tgctttaact tgttggactt
    15121 ataaaatatt cttatttcat cataagaaag attaagtgct actactgcag atattaacat
    15181 caacatcact ccaaataact tccctaagga aaaactttct cctaatatag tgcaaccaat
    15241 tattactgaa ccaactaatt ctactgatgc cacaacacct gcaactgaca actctacacc
    15301 tttagatata cctgctgcat aaaaaatata tgcaagtgca gctggaacaa tgcctaacat
    15361 tagcatacaa gataaaacat ctaaatcctt agcataattt aagatttccc aaggtcttga
    15421 agaaggaatc ataaatatag ctccaaataa gaaactgtat actaatattg ttgaacttga
    15481 aaattccttt aaagcatttt tactaatagt tggcataagt gcatatgcta ttgctgataa
    15541 taccccaagt aaaagtccaa aagcgtttaa accttgaaaa tccaaacgtc caccagtcac
    15601 tgccataatt gcaccaataa aacaaagaat aagtgaaaat aatttgcttc tagtaatatt
    15661 ttctttataa catatttttg aaaatattgc taaaaacagt ggtgatgtat atagtaaaac
    15721 tgctgcaatt gatacacccg caatgtcaat tgctttaaaa taacataaat taaacattgc
    15781 ctgacatata atacctatta ttactgaata tataattcct tttttgctta tctttaagat
    15841 ttgtggtgtc cttatagatg aatatacgcc taaaactata aatccaaaaa acaatcttgt
    15901 aaatgctact tgttctgatg tcagtccatt tcccattaaa aactttccaa ataatccaag
    15961 tgtagcccat aataaccctg ctattgctat aaatacatac cctttacttt tttctcccat
    16021 tttaaattcc cttctatttt tatttagtca atttacactc ttctttttaa gcaaaaacta
    16081 tgccatctta aatcaatata tatcgactct aaaaccctag tctttccaat aatactaata
    16141 aattttcaat ttttttatat ttatttttca cttactttaa gttgatttag acttatttta
    16201 attgtaaaat gagttatata taacttattt aaagttaaaa tagactgaaa cttatatata
    16261 aatatcaaat tttaagtata ttaatcaatt aaacctattt taatatatca ttaaaaattt
    16321 aggaggaaaa tataaaaatg aatttagatt tggaatttta tcaaaaaata ttagaagctt
    16381 cccatgatga aatatgtgtt tctgatgata aaggaataat aatatattgt aataaagcat
    16441 ttgaagaaaa ttatggtcta aaaaaagaag atattttagg aaaaaatgtt tcttttttag
    16501 aagactctgg atattcaaca aaaagcccca taccaattgt attaaaaaca aagactaaat
    16561 tttcactgga acaagatact caaacaggga aaaagcttat cataactgct acccctatat
    16621 ttgatgaaaa tggaaactta gaatttactg ttgaaaattg tagagatata actgaactta
    16681 ataatataaa aaataaactt gaagacacaa aaaagcaagt aaaaaaatat aaatctgaag
    16741 tagaaacact atacagaact gcacttagaa ttgaggatac tgtaattatg gacggaatag
    16801 ttatgagacc aatcataaac acagtaaatc atgtttctaa aacggatgta agtgtacttt
    16861 tattgggtga atctggaaca ggaaaaagct cacttgctag atatatacac cacaacagca
    16921 atagatctaa tggcccattt ataacaataa attgtgcaac tatatctcca caacttcttg
    16981 aatctgaact ttttggatat acttcaggtg cttttacagg tgcaagtact aaaggtaaag
    17041 ttgggctcgt agaattagct aatggaggaa ctcttttttt agatgaaata ggagatatac
    17101 cacaaaatct acaggcaaaa tttttgcaat taatacagga tagaactttt actccagttg
    17161 ggagcttaaa aaataaaaag gtcgatataa gaattatatc tgctacaaat gttgatttag
    17221 tttcaaaagt aaaagaaaaa aagtttagag aagatttata ctatagatta aatgttatag
    17281 aaataaaatt gcctcctctt agagaaagaa gggataatct agtggaaatt ataaaatatt
    17341 attttaatag gtactcaagt gacttcaatc taaataaaac tatttctaaa gaagctatgg
    17401 atgctattgc aaattataga ttcccaggca atataagaga attacaaaat ataattcaaa
    17461 aaatcttgct tacttgtaca gataatcata taacaataga tgacttacca aacattctta
    17521 caaaaaatat acatattacc aataatggaa ataaaacaca tatatcccaa attaataagg
    17581 ttattatatc tgactcaaaa tctactaatt ataaaaataa aaattttgac actttaatta
    17641 aagagtatga aaaaaatata attttggatg cttatgaaaa atttggtagt tcttataaag
    17701 tagccaaaca ccttgaaatc tcacagtcta aagccaatag gttaattaga aagtatacta
    17761 atacttaatt ttaaatttga taaataaaaa cttaacacta tttacatatt gtaaatttgg
    17821 ccatttactg ttattatgaa tatggttgaa attatttaaa taaatactgt tgacttagtt
    17881 tcatatattt accattaaac ttttatcata aatatcatat cataataata tatttaataa
    17941 gtctaataaa ctatacgagg tgtaaatatg ttaatgaata cccattttat tatggcaaaa
    18001 tcaatacttg ataatataga tgaaaataaa acattcttta taagcgaaaa aaattttata
    18061 tatggcaata taaagcctga tgctttttct aaatataaat taaaaaaaca ttatttagat
    18121 gagtcattta atatgattgt ttctaaaata aactatctat gcagtcttaa tatagatagt
    18181 ctttctaaat acttttcagt aagtagactt agtcaggaac taggagtcat atgtcatttt
    18241 ttatgtgatt ttttctgtgt agctcacagt gaacgttggg agtttaagca tagcttaaat
    18301 aaacatgtta cttatgaaag agaacttgga gcatttgcaa aagatgttga tttatctaaa
    18361 attaaatgtg gtactataaa tagtagtttt gagaagtttt ttactaaact ttatagtgat
    18421 tacaaaaaga aaactgatta tatgaatgat ttaaaatttt cagcttatac ttgtaatagt
    18481 gtcataaatt atatacttga ctctatttta tctaatacaa taaaatcata tcatatagca
    18541 aattgcggtt aacttaagaa tttttaaact tatataaact tataattgaa tataattaaa
    18601 atgactgctc tatagaatat aattttatac ttctctagga cagtcatttt ttatactaac
    18661 tatttatctc cattataaca tctatggcac tttttacact atctactaca taatttgcac
    18721 tttgctttac atcttccctt gccttagaca ttgcaaaact atatttaaat ccttctaaca
    18781 tgcaaatatc atttggagaa tccccaatag tagcaacttc atctggactt acatttaacg
    18841 tttttattac atgctctata cttcctcttt ttgacacact tttaggaact atatttaaag
    18901 tatatgttcc agaaaaatat atttctaaga cttcactaaa ctcacttttt agataaagtt
    18961 ctattctgga taactcttcc aaattttcag aacatacgcc tatatttcct ataagattat
    19021 caaaactact tcttttttca aaatctgggt caactataaa gtcactagaa taatgtctaa
    19081 aagcagtggt atcactaccc acaattacat cacccttata tttaaaataa agttgtgcat
    19141 cacttgactc aaatctatca atgacttttt ttactaaatt atcatctatc gttcttttaa
    19201 aaattacatt ataatcttta tcatatataa atgaaccatt ttcacataca taatatccat
    19261 tcatatctaa actatctttg ataatattat gtgcttgttt aaaaattcta cctgtagcaa
    19321 cattaaactg tactcccttt ttttctattt cttcaattgc tactatatct tcttttgtta
    19381 tggttccatt ttcatataga gttccatcta aatcacaaaa tatatgtttt atcataaatt
    19441 aaaagcctcc aaaaacaatt ttatatttta ctaatacttt aatcaaaata acttaaagct
    19501 tttctaattg tattctcaac tcattaagca aatctctagt agctcttaat cttatctttc
    19561 ttctatcccc attaaatata tttttcttta ctattgtttt tccatttata tatattgcag
    19621 tataaaccag tcccacaggc ttctctttgg ttcctccacc aggtccagct actccagttg
    19681 tagatatacc tatattagct ttaagtcctt tagcaacgcc ctcagccatt tctatagctg
    19741 tttgctcact tactgctcca aactcttcca aagtttctct ttttactcct aatcttttca
    19801 ttttagaatc attagaatat gttacacaac cttcaagaaa tacagaggat atacctggat
    19861 agtttataag agatgaagaa accaaacctc cagtacaaga ttcagccact gctattgtta
    19921 gatttttttc tacaagtagc ttagaaacag catcttctaa agcagtctcc ccttcagata
    19981 tggaaatatc tccttcagta tatacatatt taccaactct actttttatt ttttcttcta
    20041 ctggttttat taatttaaaa gcttctcttt cattttcagc ctttgcagtt attcttattg
    20101 taacttctaa ttcttttgca tataaagcaa ctgttggatt agtctgctca ttaattatat
    20161 cgagaatttc taattctaga tttgactcac ctattccata taatcttaaa gtcttagata
    20221 ctagcatttc atttgtgaat tgttgtaagt aaggtttgac actctcatta aacatagctt
    20281 tcatttctct tggaggtcca ggcaatacta ttataaattt accatctttt tttaaaattg
    20341 cccctggagc tgtaccatta ttatttttta gtactatagc atcttttgga aagtacactt
    20401 gtttcatatt attttcggcc atttttttcc ctgttttaac aaagaaagat tccaaaacct
    20461 ctagtgaagg tttatgtagt tctaatttct gaccaaagta ttctgcagca gtttcttttg
    20521 tcatatcatc accagttggc ccaagaccac ctgtagtaat tacaaaatca cttctcttta
    20581 agctttcatc aaaacattct aaaagtcttt gtttgttatc tccaacagta ctctgatggt
    20641 atacttctat tcccaatgat gcaagttctt tagctaaaaa ttgagaattt gtatttacta
    20701 tatctcccaa taatatttct gttcctacac ttattatttc agctttcaaa atttatcact
    20761 ccttgattta tagccattaa gactagtctt aagttcataa caataatttt agcaaaaata
    20821 ataacataaa taaagttaaa aaatcattta aacatatctt taaactagat tattattcta
    20881 aaaccacaca taatataaac ttcgtatata gtggtacttt catcctcaac tgttaattca
    20941 tataattaag tatgtaaata aaaagtttac tttaaaataa taaaaattaa aataggagtg
    21001 tataatatga aaatagcagt tataatgggt ggaatatcat cagagagaga agtttcttta
    21061 aattcaggaa aagagatata taataacctt gataaaaata aatatgaagt tgtaaaagta
    21121 ataatagatg ataaaaaaga tatatttaca aagataccag aagatataga ttttgcaata
    21181 cttgctttac atggaaaatt tggtgaagat ggatgtatac aatcaatact tgagactatg
    21241 gatataccat actctggatg tggacctctt tgcagtggga tgtgtatgga taaaaatata
    21301 actaaaaaaa tgcttagaga ttcaaaccta cctactgctc catgggtttt agtaaaatca
    21361 gttgatgaaa tagactatga tgaaatagat aatataggtt atccagtatt tataaaacca
    21421 aactcaggag gttcaagtgt agccacattc tttattcatt ctaaggatga agttgaagaa
    21481 gcagttagaa aaggtctgga agttgatgaa tttgtaatga ttgaaaaata tataccaggt
    21541 ggagaatata cttcattcat attaaatgga gaagtattcc ctacaatatc tataaaatct
    21601 gattcaggat tctttgatta tgaagctaaa tactcagttg aaaaaggtgc aaaggaagaa
    21661 gttgtttact tagatgaaga acttcaaaaa agagtaaacg aaatttctga gacttgttgg
    21721 aaaattttta attgcaaagc atatgtaaga gttgatatga ttataagtga aggtattcca
    21781 tatgttcttg aactaaatac tcttcctgga atgactcaaa ctagtttaat tcctagaagt
    21841 gctgctgcta gaggtattaa gtacagtgaa ctattagata aacttataga atactcttta
    21901 aattagatga aataatttga ggtggtaatt tgatattttc aaatctaaaa ttaaatgata
    21961 atgaaccaat ttatatacaa cttaaaaatt atataagtga tatgatatca aaaggactaa
    22021 ttccagacaa tagtaagctc ccttctacaa gggagcttag tcagctttta caagttagcc
    22081 gaaattctgt agttttaact tatgaagaat taaaatcaga aggattaatc tactctattt
    22141 caggaaaagg tacatttgtt aaatcaaaga ataagtcttc aaatactaca tggtcattaa
    22201 actgggattg tttagagaat acatactcta aaaaagccaa tgaattggac attataaaaa
    22261 gtgaaattcc ttggagctct gacctgattt cctttaaaag tatttctcca gatggagatt
    22321 tattcgacat ggaagaatta aaaaaatcct ttttaaatag aatttcacta gaaggacata
    22381 aattactcaa ctatggatat gcacaaggtt ataagccact tattgactat ttactagaat
    22441 atatgacaaa caagggtgct gatataagta ataaagatat actaataaca aatggattca
    22501 cagaaggctt tgatattatt atgtcatctt ttacccaaga aaaagactac ataatatgtg
    22561 aaaatcctac tcataatact gctataaaaa ttatgaaatc tcataacctc aatatcttag
    22621 gtgtagatat aaatgaagat ggtttggact tcaatatgct agaagacaat ttagttaagt
    22681 ataaaaataa aataaagttt gcatacatta caccctctta tcacaatcct acaggaattg
    22741 taatgactcc tgaaaatagg tacaaattct ataatcttat gaaaaaatac aatatagcaa
    22801 ctatagaaga tggatttaat gaagaattac tctacaatag ttctcatata tttcctatct
    22861 gttccctaga taatatgaat aatggggtcg tatatattgg tagtttttca aagattttat
    22921 ttcctggaat gagaattgga tggatatttg cagataaaaa agtaatcaat aagctagaaa
    22981 gtgtaaaaag gtgcagaaac atacatgtat cctttttaga ccaaggaatt ttatttgatt
    23041 atttaagtaa tggaggtttt gaaaaataca ttaaaaaaat acgtaaattc tatggagaca
    23101 aatttaactt tgcatataaa tgtataaaaa aatatataaa aacagaatat atcttgggtg
    23161 atggtggttt gcatatattt ataaaactaa aaaatataga tactagagtt ttattagaaa
    23221 aatgttatga aaaaaatgtt atatttatgc ctggagactt attttttaca gataactctg
    23281 gttttgatac tttaagactc ggattttcta ggttgtcttt tgaagacatt gaaattggaa
    23341 taaaaataat tggagaaact ataaatgaaa tgttctaggt taactaaata ttgttagcct
    23401 agtttatttt tatgaggtat aatatatata gtttatatga atctaatact gggggataat
    23461 atgagtaaaa agtcaaaacg aagaaaaatt aataaattaa aattaacgat tgtaataact
    23521 gtattatttc ttgctttatt atctatatat gagatactgt tctctaatcc caacaaaaaa
    23581 ggtaatataa agagtcaaga aactatgcaa aataaaaata atacaacaga tgattctaaa
    23641 aataatcaaa gctctaccaa aaagcaggaa gataataata tcaagcctac tttttcatat
    23701 tcttcaatac cagataatat aaaaaataaa atgattggta aatctatgcc tactgatgaa
    23761 cctataagct ttgatagtct atcttattta aaacttacat attatggatt tgatgaaaaa
    23821 actcatcaag gagaaatgat agtaaacagt gaactagctc cagaagtagt ggatattttt
    23881 aaggaattat acgaaaaaaa atatccaatt gaaaaaatta agttaataga tgactatgat
    23941 gctgtagatg aaaaatctat gtctgataat aatacctcat cattttgtta tagaactata
    24001 gctggtacaa atgtagtttc aaatcatggt aaaggacgtg ctatagatat aaacccatta
    24061 cagaatcctc aagtttctgg aaatgatgtt acacctaaag taagtacagt ttatgctgat
    24121 aggtctagca caaaatttgg aatgataaaa aaaggtgatg attgttataa tgcttttgta
    24181 agcagaggtt ggagttgggg tggctattgg aaaaacccag attatcaaca ttttgaaaaa
    24241 taatagatta gaaataaagg tgaattatat gaatttaatg acattggaaa atataagtaa
    24301 aagctattct gaaaaaaaat tactagaaaa tatatctctt ggaataaatg aaggggaaaa
    24361 aataggactt attggtgtaa atggcactgg taaatctacc ttactcaaaa ttattgcagg
    24421 agttgaagaa agtgagactg gtaatataac aaaaactaat ggtattagga tagaatatct
    24481 acctcaaaat ccaacttaca atgaaaattc aactgtactt gaacaagtat ttaatggaac
    24541 ttctgaagaa ttaaagctac ttggtgaata tcaagaaatc ctagaaaaac ttaattcaaa
    24601 ctttacagag gaattaaata aaaaattatt atcagtacac gaaaaaatag atgccttaaa
    24661 tctttgggat ttagaaagtg aagctaagtc agtacttaca aagcttggta taaatgactt
    24721 taatcaaaaa atagcagaac tttctggtgg gcaaagaaag agagtctctc tggcatcagc
    24781 ccttattaca ccttgtgagt ttttgatact agatgagcct acaaaccatc tagacaatga
    24841 tactatagat tggcttgagg aatatcttaa ttccagaaaa ggttcattgc ttatgataac
    24901 tcatgataga tactttttag accgtgttac aaatagaatt attgaactgg acaagggtag
    24961 attattcagt tatgatggga attattcaat atttttggaa aagaaaatgg aaagactttc
    25021 gctagaagca agtattgaag ataaaagaca aaatttaata agaacagagc ttgcgtgggt
    25081 aagacgagga gctcaggctc gtagcactaa acaaaaagct cgtttacaaa gatttgatga
    25141 acttataaat agagattctt ttaaacctga tgaaaatctt gatatatctg ttgcatcaag
    25201 tagacttgga aataaaataa tagaaataca caatatatct aaatcatttg aagaaaatac
    25261 tgttatagat aatttagaat acactttaac tcgtacagat agaattggta taataggcaa
    25321 aaatggtatg ggtaaatcta cccttataaa tatacttaat ggagaaatag agcctgatag
    25381 tggatatatt tcaattggag aaacggttaa aataggttgt ttttctcaag acgactctca
    25441 tatgaatatt gatatgaggg ctatagacta tgtaaaagaa gctagtgact atatagaaac
    25501 ttcagatggt actaggatta cagcttctca aatgtgtgaa agattccttt tcaatggtac
    25561 tatgcaatat actttgatag gtaaattatc tggtggtgaa agaagaagac tacatcttct
    25621 taaaatcctt atgacagctc ctaatgtgct tcttttagat gaacctacaa atgatttaga
    25681 tattgaaacg cttaaaatat tagaagaata cctagacgaa tttaaaggtg tagtagttac
    25741 agtatcacat gatagatatt tcttagatag aatttgtaat aaaatatttg catatgaagg
    25801 taatggaaaa attcatatct atacaggtaa ttacagtgat tatcttattt atagagagat
    25861 tcaaggaatt gaatttgaag aatctaaaag ggaatcagtt aaaaaagatg actctactac
    25921 cctaaaaaaa gaaaaaccta aaaatgataa aaagcttaag ttctcatata atgaacaaag
    25981 ggagtttgaa aatattgact ctgatataga aaaactcgaa tctaaaattg caacacttga
    26041 tgaaagtact gcaaaatttt caactgattt tactaaactc caagaaattt tagatgagaa
    26101 atctaaacta gaaaaagaac ttgaatacaa atatgaaaga tgggaatatt taaataatct
    26161 agctgatgaa atagctaata ataagtgata ttaaaataat cttaagttta ataagttttg
    26221 ctttaaatct gtaatttata aatattttaa aggaagtgtc tcaaaatgaa ctttttagtt
    26281 ttatgagaca ctctttttta tgagaaatca aatatatttt catcatttca acaatacaaa
    26341 agaggcttat ctctattttg agacagcctc tttcataatt accttctaat ttatatgctc
    26401 taatatatct ataataattc ttattatatc tatatatcca gtctttcaat atagtgacaa
    26461 ttaacttcaa tatgatttaa aaatactaac aacctttcat aaagtggatg agattcttct
    26521 ccatatttag cttctaggtt cttgcctatt tctctaacag tcctttgacc atcaatttgt
    26581 aaaaaaacaa aacttgaata ttcatctagt tctatttttt tgtatttagg tattctagct
    26641 tttaactttc taaaaaactt ttgaatttta tggtcctgtt tttcaagtat agtaacaaca
    26701 ctattttcag ctacttcata ttcaagtcca tcagtaattt taaatacaat atctaaaaca
    26761 tcattactct tgctcattat tttttacttt agataaaaca ataggtaatg ctgtaagcac
    26821 aactaaaact actaataaag caattgccat tgaatttgtt gcagcaaatc cacttggtac
    26881 ctttggagtt acaactccag ttacttgtaa tattatacct attaaaccaa tgatagaacc
    26941 accagcaaca agaccagaag ataaacttat accattagaa actttaactt ctttttcttt
    27001 ttcagtttta gatactaatt caacaaataa acgaattaat gctccaacta atattataga
    27061 agttgttgca attggtaaat agaatcctat agctatagtc attattggta aatttaatgc
    27121 atatagaacg attgccataa atactccaac aataatcata acccaaggta aactacctga
    27181 cataatacca gaagttaatg ttgacattaa gtttgcttgt ggtaatgcaa attgtacatt
    27241 atcaccagtt gctctaagtt ggtcagaaag taataaaatt actcctacaa caactataac
    27301 accaactata cttgcaattg taaagtaacg ttgcatttcg tttttgctac caccaataat
    27361 ataagttact ttttgagatt gagtataacc tccagctata gcaatagcaa caactataaa
    27421 tgaaccaaat aaaagtaatg atttattagc ttctaaatca gtccatccca ttataacaaa
    27481 cactaatgtt acaataacta gagaagctat agtcatacca gaaactggaa gatttgatgt
    27541 tccgattgtt cctgttaaac gaccagctac tatgacaaat aataaagata ataaaagaga
    27601 tatgatagct ccaataattg ccataacaat gttaccagaa attaagaatg ctgctaaaaa
    27661 tccaataact actccaccta ataaaagtat catttgtata gatgaacctt cttctccttc
    27721 tccagcactt gatttagctt taagtgtttc ttttatagaa gcgattatag ttggtataag
    27781 ttttattgca ccaataatac ctccacaaag catcatacca gcacctatat attttacata
    27841 actactagat attgctccaa catccatttg gttaagaggc attgcaggat tattccatac
    27901 catagctcca tctttagcca tatctgtaaa gtatcctatt aaaggtgcta taccaaagtt
    27961 tgataaaata cttcctgcaa acattgttaa agaaacttca agccctacta taaatccaat
    28021 tcctaaaagt agaggattta cttcaatatc aaatttccat ttgtagaatt tgcttcctac
    28081 aagactcatt acattgtttg ctacatttaa gaatgaacca gttaatacag taataaatcc
    28141 acttattaca aatccaattc ccatgtactt aattgaatct ccaccagcct ctgaagcaac
    28201 aagtgtctca gatatagcca ttgattctgg gtacataagt ttaccatgtt cttcaactat
    28261 tagatagttg tgaactatag cagcaattcc tataccaaat aaaactccac caactccaac
    28321 agctaagcct tctaagaatg taatttggct tccaattaat ataactgctg gtaatacgaa
    28381 aataaatcca cttgcaacag attctccacc acttgacata ccttggatta agtttttacc
    28441 aagaataccc tttgaacgag caaatgctcc aacaaaagca gaacctatta tagctcctgg
    28501 aatacctgcg gcaactgtaa gaccggcttt cattccagag taagttgtag atgcggcaaa
    28561 aatggcagct aaaataatac cgataatcag tacagctaca tttccaccgg ttctggactt
    28621 atctgtgata tatggaacgt aatcttttcc actaacctca ccataagcac ccttaggtaa
    28681 ttttttgttc ataaaatttt cacccctttt caatttgtat atattataac atatatacat
    28741 ataaaactta actttttatt attttacaaa tagcgagtca aaactactaa aatttaaccc
    28801 tatattatta atttctactt ttagatattt ttatgctaat tttcttttta tttttcaatt
    28861 ctactaaaaa ctattaagat ataaaataaa aaaatttttt aatgtaaaat taattttgta
    28921 aaaaaaatgc tttaaaacac ggaaaagtat aaaaaataca ataatcattc ttataaataa
    28981 attttcacca tagtaaatat atacagaaaa ttcttgtttt tatgcaaatt gattctttta
    29041 taaaaataag tgtcataaag aaatgtctta aatcacttta tgacacctat cataataaaa
    29101 aattattctg gtaatgctct tttatttact tttccgattg gtgtaactgg tatcttatat
    29161 atcctcatta ttattgttgg aatcatatat ggaggtagat gctcatttaa atattctcta
    29221 atagttcttt catttatctt accactatct tcctcatcaa ttacataata tgcacatata
    29281 tacatatctc catcatcatt tgttctcgat atacaaacaa cacttttaat ttctgtaata
    29341 ttatttatta tattttcaat ctcatatagc tctatcctaa actcatcaat ttttacttga
    29401 ttgtccatcc ttccaatata atctaaattt ccatcatcta accatcttac taaatcacca
    29461 gttctataca ttaacttatt atgttcacaa gttttgtaag gattctctac aaatacttgc
    29521 tctgttagcc cttttttatt taaatatcct cttgatattt gaatgcctga tagacatagc
    29581 tctcctggtg ctccaattgg acatagtttg ttctttttat ctaatacata tgcataagta
    29641 ttaaatatag gttttcctat tggtattttt ccatattctc tgtccacatg aaaagaagtc
    29701 gatacaacag taaattcggt tggtccatac tcattatata gttcataatt acgctttcta
    29761 tatcctttta atctttctcc tccagtctgt acaactctaa gtgaattatt attgcaattt
    29821 tgtataaata accttgcaaa tgctgttggc aatgctagta tagttatgtc attttcctca
    29881 cagtattcat ttactgtata ttcatcaaat ttagcttctt caggcataat atctattgat
    29941 gcacctacaa gcaaataagg gaatagttgt ttcattacag catcaaaact gaaacttaag
    30001 tatataccac atatatcatt ttctgtagcg cttatagatt ttacgctata ataacacata
    30061 tttactaaac tcttatgttc tatagctatg gtctttggcc taccagttga ccctgaagta
    30121 gatatcgtat atgcacaatt tgatgatgtt attttttcag ttaattcata tccaagctta
    30181 aacatttctt catcatttat atcgagtact atggtattct catttacaac cttacttttg
    30241 agttcatctg tagttatcac tacttttgca ttactatctt caagaaggta attcaatctt
    30301 tcttctggat tacttgtgtc tattggaaaa aatgctcccc ctgatttcat aatccctatt
    30361 gctgtaataa ttatgttaat atctcttggt aacattacag ctactatgtc ttcactttcc
    30421 actcctatat gatttaaata acctgcaagt ttatcagtta cttcatccaa ttctttatat
    30481 gttaactttc tattttcatc cctagcagct atattactag gtgttacctt aacttgctcc
    30541 ctaaataaat caacataact tttatcatag ggtacttcat attgattatt attaaagtct
    30601 tccaataata ctttttcttc ttccttacat acaaattcta aatcttctat taaaatatca
    30661 ttatcttcta ttatttgctc tattatataa tcaaattgat ttaaaattct tctaatagtt
    30721 tctcttttat atatagatgg tttatacttt atttttattt taagtgccct cttagtatat
    30781 actattacag ataaatcata tccttttttt tctatgtcat aatcatatga taaatcaaaa
    30841 cttttagcta taaatattgt gtttataagc ttagtattta gatgattttt attctctata
    30901 tctgataaca aatagtatcc atactctaaa gacctgctcc actgcctttt tagcttcctt
    30961 acaacatcta taaatttttc actttgtcta actcttactc ttattggaat tatattcatt
    31021 gttttaccaa aaactacatc atcttcatat atatactttt gaagtataag gccatatata
    31081 gtttctatga tagagtctat gctaatattg ttcactttag aatattgaat taacctttca
    31141 tgtttctcaa tattcatctt aaaaacctca tctactactt catcagaaca atctttataa
    31201 aaaaaatcat ttggaatttt tgctatattc gtataatcat ctaacaaatc catccaataa
    31261 ttcatagctc gttctaaatt aacttcatac atatcaaaat tcccccttac tactaagtct
    31321 atagaaaaaa ttcttttgga attttatttt cacaatatat aaatatatta ataatacata
    31381 tgcaagctct aaaaacatga gcttgcataa aattacactt attatgacta ctaaattcgt
    31441 aatatttaca atgtttaaaa tatattataa cacatatatg attttatttt tctacattta
    31501 tataatatat aaattacaaa tagttattta actaatatat aacaatacct tttggaatat
    31561 gatatattat attaattaaa tttttataag ataagttata cttataggag ggaaccatat
    31621 aaatgaatat ttatgctcat agggggttta gtggaaagta tccagaaaat actattctag
    31681 cttttaaaaa atgtttggat atggatatat atggaataga acttgatgtc cacagaacta
    31741 aggatggaaa aattgtagtt attcatgatg aaaaggttga tagaactttt aatggacatg
    31801 gttttgtaaa agactttact ttaagaaaat taaaaactct aaactcatct tttgaaggat
    31861 atcaaagcaa taaagaatgt aaaattccaa ctttagaaga agtattaatt ctaatttcac
    31921 ctacagacct tattttaaat atagaactaa aaactgacaa aataaactat cccaatatag
    31981 aaaaagacgt tttagagctt attttaaagt ataatatgaa aaatagagtt cttatatcta
    32041 gtttcaacag caatagctta aaaaactttc ataaattaga ccctagtata aaaacaggat
    32101 tattgtgtta tttacctata aacaatgtag tcaattttgc taaatttctg ggtaatagtt
    32161 accttcatcc acctctagtt ttagtaaatg aatctctaat tgaactttgt cacaaaaatc
    32221 tacttggtgt caatgtatat actgtaaatg aagaggatga tatactacac tgtctaaaac
    32281 tcaatgtaga tggtattttt actaactatc cagatattgc ttcaaatctt ttacactcaa
    32341 aacaatacag ctaattatac aatagtttgt actccttgac ttttatataa ttaatatgta
    32401 caattttatt aaatttatct tggaggtata actatggata acttattaaa tgaacttgaa
    32461 gctttaaaga gtaatttaga taatctacca atagaaaaaa tagaaaatta tgatttgagt
    32521 aaaactgctt tatttataat tgatgttaat aatggctttg caagacaagg tgcattatac
    32581 tctcctagag tagagtcttt aataaagcca attgaaatgt ttacaaaaaa aatatcaaac
    32641 aaattaaata gagtaatagc atttactgat tctcatactc ctaaatcaat agaacttttg
    32701 agttatcctg ttcactgttt ggaaaatgat gtagaaagtg aattggttga tgaacttaag
    32761 tcgatagaaa acctacaaat tcttcctaaa aattctacta atggtttttt tgcattagaa
    32821 aatttggatt ttgataatat agataatata attatagttg gcgattgcac agatatatgt
    32881 atatatcaat ttgcaataac tctaaaatca tattttaatc aacataatat tgaaaaaaat
    32941 atagttgtac ctatgaattt agtagatact tatgatattc ctaacgttca ccctgctgag
    33001 attttaaact tagtattttt caacagtatg attcaaaatg gagttaatgt attaaaagag
    33061 attcgttaag cttctaatac tttacatccc atataataca attatcagat atttattttt
    33121 aataaaattt ctaatagaaa aacacagttt tagtgagaag attacaattt aaaacactat
    33181 ctattattac taatcttcac aatataaaaa atcgcagttt agatattcct tatacaaatt
    33241 tataaggaat aataaattgc gatttttatt tttaagtagt acaattaatt gatactactt
    33301 cagtatttaa attcattttt taataatcat acttattcgt agtttcgcac attactacct
    33361 ttattttttt attaaacata ttcttatatt ctaataaaaa ctcatttagt tctgaatcca
    33421 taagatttat ttttctatca ctacaaagca ttatcttttc ttggtcgatt attacattaa
    33481 tatcatttaa gtcatttttt ataaatgttg ttatacaact ctttggttgg attttttctc
    33541 catatttctc ataaaatcct gcactcttct taaatgactc taaatcttct gtagatactt
    33601 tgctggaagt attattactc ataaaacctg ctgtagaagg gtcgattcca aagtttctaa
    33661 gttgtttttc tacttcttca gtgtccatac catatctctc cataaattgc ttttgtattt
    33721 tcataaattt ttcttgagat atgttgttat ctctcatata atcgaatatt tttcttgaaa
    33781 actcagccat agacatcttt ccatccataa cagaaaaata taagttatat atgtattgct
    33841 caaatttatc tacatcagaa tctttaactt tgttctttag ttcgttaaag tctattattc
    33901 tatcatcaga catttttcat cctcctagct aaatttttac ttgtataaga ttataccata
    33961 tttctattat atttatatac acactatttt tttaatttaa cgattttttc tgtagcatct
    34021 aattcgcaca ttctgcccaa aggaatagtt atcattggga tacaatgtcc tgactgaaga
    34081 ttatatatag aaggtttatt gaccttattt gcaaattcta ttagtaattc catcaaatca
    34141 ttttcttcaa tacaatcctt aaaatctcca aaaattatac cattacattc ctcaagtttt
    34201 cctgaagaat atagttgtgt taacattcta tccaatttat attgaggttc tccaatttcc
    34261 tcaataaaca aaattttatc ttttgcatct atttcatatt ttgttcccat tgtggcaatt
    34321 attaaggata aatttcctcc cattattatt ccctctgctt taccttcaca tacagtataa
    34381 atcttttctt cttttggatt ttctaaatat aattcatctt taaattctaa agcatttacc
    34441 aatgatttat aggtaaattt atcccattta cctacatttg ctgccattat tccatgatat
    34501 ggtaaaagac cacaattttt atagaaagct aaatttaaac ctgttatatc agaaaaacct
    34561 ataaatggtt ttggattttg ctttattata tcataattta ttttatccaa tattcttgtt
    34621 gttccataac ctcctcttaa gcacataatt atatctacat ctttatctaa aaacatatct
    34681 tctatatccc ttgctctaat atcatcatta ccagctaaat aacctttata atttaaacta
    34741 caactttcag aaaacttaac ttcgtaacca taactttcta aattaaactt tatttcctcc
    34801 aaacttgtat ttcttaatgg cccagatggc gcaattattc ctaacattta aacacctctt
    34861 cttataaaat gatatattct tctccatact aaatatctct aatataatta taagatattt
    34921 tatttgtact tgatacataa taatgattta cataaaataa tataattaat gaagaaaaat
    34981 aaatttttaa tatagttagg atgtgtttta tgcttaatat aaaaactctt tgtcatgaga
    35041 taaatgattg ggttataaat ataagaagag atttacataa gactccagaa cttggattag
    35101 aagaatttca aactaagaaa aaaattatta aatacttaaa tgaaataggt ataaattata
    35161 ttgaatataa gaatcataca gggataactg catacattaa cgtgagtcca aactttgaaa
    35221 cagttgctat aagagctgat atagatgcct tacctataac agaagaactt aattattctt
    35281 ataaatctat taatattggc aaaatgcatg catgtggtca tgatgcacac actgctattt
    35341 tactgggtac ttgtaatata ctatttaaat taaaggatta cttaaatgta aatgtaaaat
    35401 tcttttttca acctgccgag gaaactattg gtggggctca acttatgata gaagatggat
    35461 gtcttgaaaa cccaaatgta aaatatatat ttggacttca tgtaaatccc aatatcaaca
    35521 aaaatctaat tgaattaaaa tacaacactc taaatgcttc caccgataca cttcaattaa
    35581 ctgtacatgg ttcaaaatgt catggagctt atccacatca aggtattgat gctattgtta
    35641 tatctgctca tattattaca gctctacaga caatcgttag tcgaaacaca aatccaactg
    35701 attctgtggt tatttctcta ggaaagattg aaggtggaat caaagaaaat atagtttgtg
    35761 acaaagtggt tataaggggt actttgagaa ccttgactcc tgaaactaga gagttttcaa
    35821 aaaaacgaat tagagaaatt tgcgatttta cttgtaaaac atttggagga agtatttctg
    35881 ttgaaattga ggaaggttat ccagctctta tcaattcaaa ccatctagta gattacgtca
    35941 aacaaaatgc tgtagaattg tttggtgaag aaaatattat ccttaaagac tcgcccactc
    36001 ttggggctga agacttttcg tattttctaa gacactgtga aggagctttt taccaccttg
    36061 gttgtgcaaa tcgtgaaaaa aacattactt cccctttgca tacctctact tttgatattg
    36121 acgaagattg ccttattact ggtgtcatgc tccatgtaaa aaatgtatta tcattctaac
    36181 tattaatatt tttatttatt attttatatt gaccctcaca tgatgtcatg ttatacccta
    36241 aaattacaaa tgataaatta aatagttgga ggtaatatta tgaaagaaat attaataaat
    36301 cctataggta aaatatgtat tcaaggcgaa gaggtcttta ttaaattaga caaaaagtat
    36361 gtacctgcat taaatgaact cgacgatttc agtcatttaa atgtattttg gtgggctgat
    36421 gggtttgata atcctgaact aagaagtatt ttagaaaccc caaaacctta taaaagtgga
    36481 ccagacgtta taggaatatt tgcaacaagg tcacctataa gacccaatcc aatagcattg
    36541 actgctgtac aaattatcaa tatcgaccat gaaaatggca taataaaaat accatatatt
    36601 gatgctaatg ataatagtcc tgttattgac ttaaagccat atactccaag cgttgatagg
    36661 gttgaaaatc cgtccgttcc taaatggtgt agtcactggc ctaagagtgt agaaaaatca
    36721 ggagaattta attgggaaga tgaaattgaa ttttaaatta cttttttctt gatttcatta
    36781 acttgttttc cacatttatt ttatttacac ttaccaagat tttatgtcac atatacatat
    36841 aatattaggc tgtattatat aatacaacct aatattatat aataaatttc tatttttccc
    36901 ttaaatcatt cacattcttt ctaagctaca taagattttt ctattatttc tttttgagtt
    36961 taatttagca ttatgttgag gaaaaaacat ttcatgcatt ttaataaatt aaatttttct
    37021 tttattctgc gattttataa taatcaattt aacttaaaaa taatacctaa ctattttaac
    37081 tatgttaaac tagtaaatgt aaccacttat atgttacaat tttatataaa catcaaatat
    37141 aaaaaactat ataaataaat gacacatagt gttatatttt tttataccaa tttagttatt
    37201 tttcagttac agatttaata atagttaata gtaagacata atatttttat gccctttatt
    37261 gattatgtat tttctgttat ctgttattat catcaataat aaacataagg gggtatatat
    37321 tatgaaattg tatttaagtg ctgatataga aggtacttgt ggtattgtaa attgggatga
    37381 aacaaaactt gaatgtgaat tttcgcaaca ctatagaaca caaatgagta aagagataac
    37441 agcagcatgt gatggagcta ctcaatctgg tgtacatgaa atacttgtta aagatgcaca
    37501 tgacagtggt agaaatatta atccaaatat tttacctgaa aacgtcaaaa tacttagagg
    37561 atggaccaaa gacccactag ttatgatggc aggaattgat gaaagctttg atgcatgtat
    37621 attcaccggc tatcactctg gagctacttg taatggtaat ccactttctc atactatgga
    37681 tattgattat gactatttta aaataaatga tgaaatagca tctgaattta ctataaatgc
    37741 ttatattgct gcatattata atgttcctgt agcattttta agtggagatg aaatgctttg
    37801 tgagagtgca aaaaaactaa atccaaatat agtcactgtt cctgtgtcaa aaggaattgg
    37861 aaatggttca atttcaatcc atccaaacct tgcactaaaa aaaattgaaa aaggtgtcaa
    37921 aaaagcttta tctggagatt tatctaggca cttaataaaa ttgccagata aatttaagat
    37981 agaaataaaa tttagagaac attataaagc ttttaaggcc tctttttatc caaatatgaa
    38041 aaaaatagat tctcaaacag tactatttga aacagaggac tattatgaat ttttaagaat
    38101 gttattattt atataaattt catatcataa attaaggagt tgattaagat aagtaataaa
    38161 agaaggattc ctttaggcga atttatttct gtatttttat tttttgctgt tttttttggt
    38221 ataacttttt gtattttcac ggttatagga attggcttct tatcattctt aggatttgaa
    38281 tataaatctc ttggagctgt attaattttc tttttaatat atttttgtat aaccactcca
    38341 attgattttc tatgcactac tattttagat atattcagat atgtaaacaa attaccatac
    38401 tcaatatata aactttgcga atttataatt gattttatac taacttttct agctatgaac
    38461 ataattgata cctttatgga ttcagtaacg attcctttaa gtacagaaat cttattcgct
    38521 ttactttctt atcttttatc agaatgtatg gatttttttg atagggataa gaaaaaacct
    38581 taataaaaaa gatagattcc ttaatagaac acatattttc gtatttctat tatttaatct
    38641 atctttattt tatttaataa atttttatta attaaaatat agtttcttct atctccttag
    38701 tcatttgctt agcactatca aaaaattctt ctatatacac tacttcatca ctgaccctag
    38761 aatattctgc tgcaaatgcc attacatgac tttgtatagc ttcttttgct gctactctac
    38821 ccttttctag ttctttattt gaaactaatt taataaattc agctataaga tttctatcat
    38881 attcctctac catattctgt tgatttgatg gattcataac tatttcttcg ttttttccaa
    38941 attctttaat tcttatctca tttttattta aatccccacc aacttcacca tggctaaaca
    39001 ttaactttat agttcttcca ttttctttag taaatgcaca taaattaaaa gtagccgtca
    39061 ctccattttc aaactgtagt atatttacca tattgtctac aacattatta tcacatctgt
    39121 aaacacatct tccatatgga cttgtcttaa gtatatttaa tagattctct tcagttggat
    39181 ttatgtgaac agctctattt atacttctat ctttttctaa ataaattctc tttgctgaat
    39241 atggacattt tttttcaact aaacactgaa gacaattttg tgccatctct ccactagcat
    39301 tttggttatt aagatgcttt aagcttccaa atgcagatat ttttttgcat ctacttccta
    39361 ctaaatataa caaaatatcc atgtcatgac aactctttgc taaaattaaa ggactggttt
    39421 cattgctatt tctccaattc cctctagtaa agctatgtgc aaaatgccaa tatcctatat
    39481 tttcattata ttgtatacta actagctctc ctaatttttt gctttctaca atttctttta
    39541 atttattata aaatggagaa tatctcagta catggcaaat cataaaaatc ttatctttat
    39601 acttatcaca caagtcatct atatgtacca aaccatctaa actattagac attggctttt
    39661 ctaatagtac atgataacct ttttcaagag ctagttttgc tacatcataa tgtctatcat
    39721 catttgtagc tattattact gcatctgcca tcttgtcatg tttaaaaaag tcttctaaag
    39781 tttcaaatac atttttacta tctaggttat atttttttgt aaatagttct cgtcttcctt
    39841 ttttaggttc tgctacagca actatttcac atacatcaga attttcataa atatatggag
    39901 catatgcata cgttcctcta ttacctgctc caatcacagc aactttcact ttttccatac
    39961 tttaatttat cccctttata ttatttatac tactctatta tagtctattt ttacagacat
    40021 ttggatattt ttaataaaag aaacagcagt tataattttt caattttaac tgctgttata
    40081 agttaatata ccaaacattt ttaattaaat tttctttaat tttaatacaa agacttaaat
    40141 attcaataca aattataaaa acacttttat ctagtttact tcttcttttc tttgtctaat
    40201 ttatctaact tcttattgta taaaaacata taaaatgctg ccgaaaatac tattaaatat
    40261 ccaacaacac ttaacatatc tggatagaca ttgaataaga atatacttaa aattgctgaa
    40321 aagattatat tactatagtc aaatatagag atttccttag caggtgcata tttatatgct
    40381 agagttattc caaattgacc tagacttgca aatactccac ctagtaatag atatataagt
    40441 tgcataaggg tcattggttc atatactgca aaagcaattg gccctacagt aactaatgaa
    40501 aaaactgaaa agaaaaatac aattgtatag taatcttctc tatctccaag aactcttaaa
    40561 caagtatatg ccattgctgc aaatacagct cctgcaattc ccccaagata tggaattact
    40621 tctacactaa atgttggttt tattatgaat aaagctccta taaatgcaat tataatagct
    40681 cctatctgct ttacatttat tttttctttt agagcaattg cacaaaatat tactacaagg
    40741 aagggactca ttttatttag catattagca tctgaaagca tcaacttgtc aattgcatag
    40801 tagttaaata taactcctag agttccaaat attgacctat ataaaagtac ttttaaattt
    40861 tcttttttac cagttagact tcctttatgt tttatgataa gccaaaaagc tattatagct
    40921 gataccagat ttctaaagaa cactttttga aaacttggta aatctccagc tagctttacg
    40981 aatgcagaca tcattgcaaa gccaagcgct gatgctatta taaacattat accttttatt
    41041 cgatttgatt tgattgtgct actcatacgt acctcttttc tatataaatg tataaagcca
    41101 tattaattaa aaacttagct tatacattaa ataataatta tctaaatatt ccaatttata
    41161 ctataattaa aagtgtaaac tatgtcaagt aactaataaa tcttttcaat taataacaat
    41221 aataattata gctaaaaagt tatatgtttt tat
//
LOCUS       DAMJXI010000032        40577 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.034, whole genome shotgun sequence.
ACCESSION   DAMJXI010000032 DAMJXI010000000
VERSION     DAMJXI010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 40577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40577
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.034"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(72..809)
                     /locus_tag="PC465_002130"
     CDS             complement(72..809)
                     /locus_tag="PC465_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649424.1"
                     /translation="MTKQKKVIWIILGIIIFVFSVFLGLGYLGQITGGNSLIQRTEIN
                     DKYVPAEITKYYPIEDLNSKESLLSDENYANSIQDALLSASIEFEQGEEYKAHIDKII
                     KEFENENYKSVLYISEKNDIESSLTFSKFKIKEIDGKKRYAYITSVHEVIKKDRPYDK
                     DTMSLLKSQLALSDSLQDLNISPDNSRFLYGFVHDEDIYNAKIENKKPDEIIYFELCE
                     KPFYFWYYENFQSDKSGKSLSIEIERE"
     gene            complement(1160..1294)
                     /locus_tag="PC465_002131"
     CDS             complement(1160..1294)
                     /locus_tag="PC465_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005610222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2649425.1"
                     /translation="MINENLKSLRKINQYTQEELAEKLNVSRQSIAKWESGVSQTKGY
                     "
     gene            1772..2521
                     /locus_tag="PC465_002132"
     CDS             1772..2521
                     /locus_tag="PC465_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440038.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HDF2649426.1"
                     /translation="MILYFSGTGNSRYVARKIAQELNDELISLNQLIKEEKTDELISA
                     DKPFIFVCPTYAWRLPIVVTDFIKETKFLGSNRVYFVMTCGGDTAKSINYIQKLCKYK
                     EWQLKGMAEIKMPENYIALFSTTDKETSKQMIKEADKQIYRIISDIRNENEFETITPS
                     GLGGTIKSGIINTVFYKTIISAKGFHYTDKCIGCGKCVELCPLNNINLKNKKPVWKNN
                     CTHCMACICGCPTEAIEYKNKTQNRERYYLE"
     gene            complement(2688..3053)
                     /locus_tag="PC465_002133"
     CDS             complement(2688..3053)
                     /locus_tag="PC465_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2649427.1"
                     /translation="MEKECQQRMQEITSKFKECRKAISAMGDETRQLILIALLESDFN
                     GIRVGEITKKTHLSRPAVSHHLKILKEAEIVNLRREGTKNYYYLDSKKSQWKSLTELI
                     NLIFVGIQHISENDIRKGD"
     gene            complement(3069..3845)
                     /locus_tag="PC465_002134"
     CDS             complement(3069..3845)
                     /locus_tag="PC465_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2649428.1"
                     /translation="MKYQHIIEVDKELCIGCGLCKNDCPVNNIIIENKKSVIKKQDCL
                     MCGHCAAICPTKAIALTGFDEPPIELTNKPKLDSDELLMAIKSRRSIRKFKDKEVSSE
                     IVKQIIEAGRYTPSAKNSQDVSYIVLDNKKSIYENEAVKFFRKIKPIANIAIKYSKEV
                     EIDDNFFFKHAPIAIMIITKDKISGSLAASNMALMAESYGLGVLFSGYFSDVANNSPK
                     LKKLLGLKRSNHVLTTLVIGYPDVKYRRTAQKEVATVRYL"
     gene            complement(4256..5683)
                     /gene="ascB"
                     /locus_tag="PC465_002135"
     CDS             complement(4256..5683)
                     /gene="ascB"
                     /locus_tag="PC465_002135"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDF2649429.1"
                     /translation="MSFKNDFLWGGATAANQCEGGYNEDERGLANVDVCPTGKDRTAV
                     ITGKLKMFDFDDEHYYPAKTGIDMYHNYKEDIKLFAEMGFKVYRMSIAWSRIFPKGDE
                     ETPNEKGLQFYENIFKECKKYKIEPLVTITHFDCPMHLVKKYGAWRNRKMIGFYEKLC
                     NVIFRRYKGLVKYWLTFNEINMILHAPFMGAGICFEEGEDVEKIKYQAAHHELVASAI
                     ATKIAHEVDSNNLIGCMFAAGSVYPYSCNPNDVWEATKLDRENYFFVDVQSKGKYPNY
                     ALKYMEQKGITPEMEPGDIELLNKYTVDFISFSYYNSRCVRTDENADDMAEGNIFISA
                     KNPYLSYSQWGWPIDPLGLRITLNHVYDRYEKPLFIVENGLGAKDIADENGYVEDDYR
                     IDYIREHIKAMHDAVSIDGVDLLGYTTWAPIDLVSAGTGEMEKRYGFIYVDRDNSGNG
                     SLRRMKKKSFEWYKKVIASNGEDLY"
     gene            complement(5744..7672)
                     /locus_tag="PC465_002136"
     CDS             complement(5744..7672)
                     /locus_tag="PC465_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2649430.1"
                     /translation="MGKYKQLAQEIVNNVGGKENISGLVHCITRLRFTLKDESIANDN
                     VLKNMEGIVTVMKSGGQYQVVIGNHVEAVYKDVVEIIGLDDSSTSSETKKSGNILDKG
                     IDIISGIFQPVLGIMAACGMLKGFNALFVAMGLYSDVSGGYMVINAAGDALFTFLPLF
                     LGYTSAKKFGLKPMLGLALGAAVCYPAIQGSSISVGADVMYTLFKGTMFASPVYIDFF
                     GLPIVSIDYTGTVVPIIFIVYFASRCEKLFNKCVPDLVKFFFVPMLTLLITVPVALIV
                     IGPIATFGSTLISQIVISIRDFSPLLAGAIVGFTWQILVIFGMHWGFIPVYINNVMTL
                     GYDNVMMPFFACTFASSAVVLAIFFKTKDKKLKEMAIPNFISGIFGVTEPAIYGILLP
                     LKKPFIISCIASGIGGAFYGFFNLRKFITGGMGIFELPAMIEPDGGMGNLIVALSGIA
                     ISMVVAFVLTMILYKDEKVEESKKVRNKGKEEIKEVKSTKLEREIVTSPIKGEVLKLS
                     DIEDAAFASGVLGQGVAIIPSDGKVVAPVDGVVTTLFPSLHAIGILSDTGVEVLIHIG
                     LNTIQLEGRGFEACIKQGDRITKGQTILNFDVDAIKELGYSTVTPIVITNSSQFLDVV
                     ETESKNIELEDNLITVLF"
     gene            complement(7817..8659)
                     /locus_tag="PC465_002137"
     CDS             complement(7817..8659)
                     /locus_tag="PC465_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2649431.1"
                     /translation="MIINKILNNNVIITLDDNDEEVIVMGKGIGYQKSKGNLIDKTKV
                     NKVFRISNKEISNKLQELLNNIPIEHMKLSSEIIEYAQIKLNKKLNESIYISLSDHTY
                     SAIQRMKEGINVKNAILWEIKRFYKEEFEIGMKALDIIENKTGIKLPEDEAGFIAFHI
                     VNAQLSEGHTLASDITKLIQEVLSIVRYHFRIEFHEESVFYYRFIMHLKFFAQRLLLD
                     SAHEGETDKELLSIIKSKYNKEFECVVKIKNFIKKQYNYILTDDELIYLTIHLAKVVK
                     DSNM"
     gene            complement(9173..11674)
                     /locus_tag="PC465_002138"
     CDS             complement(9173..11674)
                     /locus_tag="PC465_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2649432.1"
                     /translation="MIFHEVYKIYSKNSLKNNKLLKISCIISIVFATAILLFTRVLTD
                     TYSSEVKRNMAITNGGDIKIQNIEYNKYYFTSEQIDKLEELKGKESIDFQLGSSMNTN
                     ILSNGMIESTELTVVNNIKMQNTYLKLRNENDIVLSQKTANKLNVNIGDKVFLKLHSS
                     VYDDTYFKVSDIIPKRFSLSTAQKEAEVGQEVVGESYVYLPNETKYNVAYINIINKEN
                     VKNIKNEIKNVFKNHFEVRTTDELEQSIIKRISMQLDSINLIGAISLLSTGICLCSTF
                     IVFILNRINDFSTFKALGIKKRSLSFLVFTELMSITIKGIIIGIILGIPITIFYINLQ
                     HINLFNISILSIIKNIFISIVIIIIETSIFSLIPISFVKKIHYEGINRDNSMLSSYKF
                     NFIPDIILVIFLTSISFTIYVKSFLGIFFILGLILLDLLVYSLIYALLKMVCLIKKII
                     KGKYSITFIYLNNDCKTNAFSSSLLTITIIFVLLLFMISEITFAMFSNYEVDNSIKNS
                     IVYQTTLEGKLITDKKLIENDIDYFQYYPIKIDSIESVNNISVNDYIEKIPYENRKDV
                     MNDLNDLSVDLFNTKQTILKSDLEYGNWFKENDKENSIIINNYLHRYLIDYKLGDTVK
                     LRINGKKIDFKVIGFLSPKSLNKGVDLGYININENISPKTLDLSKNQPVIYFFKEKLD
                     NTLLSKLLHNDKYANLEDYNDFAYSMKTYVDDQKSLLLNIIFAVSLSSILLILTSQII
                     IFIRRVLDYQIMYRVGMSKRKLIKIGLLEMIIVSIIQSTLIAIFYELFRFLLISLLQR
                     AYNINYLLILIEFLVVLSINCFIFILAQRNIKLDL"
     gene            complement(11686..12345)
                     /locus_tag="PC465_002139"
     CDS             complement(11686..12345)
                     /locus_tag="PC465_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003410138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2649433.1"
                     /translation="MIIEVSNLSKVVDLLNTELTILRNIDLYIEEGEFVSIMGASGSG
                     KSSLISILSGLDKNYTGNVKVCGENLSKLTDDELAEYRNRKIGIVFQSFNLITSMSVE
                     ENIKLPLIFSDNKDYKIVDKMIKKVGLTSKTKNNIKQLSGGEKQRVAISRALVCSPNI
                     LFADEPTGSLDSTNSHAIMKLFKNINNEYGTTIVMVTHDIQMAEYSDRIISIKDGTII
                     K"
     gene            complement(13259..14662)
                     /locus_tag="PC465_002140"
     CDS             complement(13259..14662)
                     /locus_tag="PC465_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2649434.1"
                     /translation="MKNKYEEVAQLIIDGLGGKDNIIDLTHCMTRLRFILKDEKKVNA
                     DKLKSIDKVVGVNSTSTQYQVIIGNEVGVVFNAIINKGINTTGDIKSDIKNKNKKNSI
                     LNNIIDTIIGCMTPMIPALTASGMIKVILSLCTTFNWLSSNSSTYRVLDIIGDVAFYF
                     MPIILAINAAKKFNVNTSIAVIVVGVFLHPNFSAWVSSGDPISFIGVPIQGVIYAASV
                     IPALLTVWMMSYIEKFIDKLTPSMLKTILNPTLVLLISAPIALIVIGPIGNFLGEGLA
                     SIINLLQGRLGFIMVCLLAAAMPFIVMTGMHHALTPIFISAFATTGQESLILISQVCA
                     NLAQGGATLAVALRSKDSKMKQLASAAWISAIMGITEPALYGVTLKLKKPAMLASIGA
                     GIAGLFAGITHVTLYVPQNSIMAVLGLSGEKGISNIVNGLIVIFIALVAPFIMTYVFG
                     VEKNVKEGIGKLRKCVK"
     gene            complement(14701..15372)
                     /gene="pgmB"
                     /locus_tag="PC465_002141"
     CDS             complement(14701..15372)
                     /gene="pgmB"
                     /locus_tag="PC465_002141"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDF2649435.1"
                     /translation="MKAVLFDLDGVITDTAKYHFEAWHEIAKSLDIEIDETFNEKLKG
                     ISREESLDKILLSANKVDSYTKEEKLKVCEEKNNIYIKLINSLTYKDILPGINELIKE
                     LKKNNVKLGIASASKNAPRILESLGIKDEFDCIVNPSLLKRGKPYPDIFIEGSKILNL
                     KQYDCVGIEDSYSGIKAINAANMTSIGVGKKEVLGKYDHIVEDTSLLNYNTLLQAWSK
                     KINLD"
     gene            complement(15374..17764)
                     /locus_tag="PC465_002142"
     CDS             complement(15374..17764)
                     /locus_tag="PC465_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HDF2649436.1"
                     /translation="MSLIFTTKDQLIEQGFSKDTIKSNETLFTLANGHLGVRGNIEES
                     DFNNEYVDNMGTYVNGFYEESPITYGESAYGYAKQNQTICKLPNAHIVNFSIEGDYFD
                     LSKGITSEHSRILDLNEGILKRSFIWENSCGRKVKVSIERLVSQDIEELMMISYTITP
                     LNFNGKIKFKNKMENSMEKFNCEKVDDPRVASINKKQFKINVKKYNNKYFMNLVTERS
                     RLGLWCGFDSYITCGNITNETYNVSDECIEREIEVYAKKDERLNLEIVVGYSRVYSDL
                     NLNEERLKSLECLESLKCLESEAHLKSLELVLREACNIGFDKVKNIQRKKMNEFWTTS
                     DVEIEGDKTLQLGIKTNLFHIYQSAGRDGKTNISAKGLTGDGYEGHYFWDTEMYILPF
                     FIYTQPSIARALLDYRYSILDASRERARELGINKGCLYSWRTINGNECSAYYPAGTAQ
                     FHINADIAYGIRTYFEATNDEEFMMQNGLEILIETARFWVEFGDYIESKNNKFCINGV
                     TGPDEYTAIVNNNYYTNLMAKYNLIYAVQMVDKFKHNLFSNEVFRKVKLQEYEVKNWI
                     NAAQNMYLPYDEEKKISKQDDSFLEKSVWDFKNTPKEKYPLLLHYHPLTIYRYQVNKQ
                     ADTVLSALLFPDEFSLEQKKRDFEYYEKITTHDSSLSRSIFGMMASEIGNHEKAYNYF
                     MDTALMDINNLQKNTSDGIHAANMGGTWMSLVYGFAGMKIKNDKLSFEPRIPKHWKNI
                     KFNILFRDNLVSVNIEEYKSYYKLIKGRNITILHDNKEIKLSKNIIEVNNCFKGSN"
     gene            complement(17790..19238)
                     /locus_tag="PC465_002143"
     CDS             complement(17790..19238)
                     /locus_tag="PC465_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HDF2649437.1"
                     /translation="MKLGKDFLWGGAISANQSEGFYLDGGKGLSQFDKLPLNDKRLKD
                     VCLDEDNILNENNQYYPSHIGIKFCENYKEDIAMLAEIGFKCFRFSISWSRIFPTGEE
                     SEPNEKGLQLYDNIIKELKKYNIEPLITISHFDIPYSLVEKYSGWADRRVVNLYVKYA
                     EILMKRYKDDVKYWIPFNEMNMIIHIPYIGAGLTFIADENQLQKKYQAAHHQLLANAK
                     TIEIGRYINKEFKFGCMLAAGKTYPYTCKPEDVFATLEHERHNLFFSDVQVRGVYPSF
                     MNYYLKSNQIKLIIKEEDLSTLKDNTVDFVSFSYYSSACSSARAEGLEKSKANGPETI
                     KNPYLPKSNSVWQNDPVGLRITMNQLYERYQLPLFIVENGLGTQDIVNEDGKIIDDYR
                     IDYMKEHIKNMILGVNEDGIELIGYLMWGCIDVTSVSEGKMTKRYGIIHVDSDDYGRG
                     SFKRTKKQSAFWYKKVIETDGEILFNDMETHA"
     gene            complement(19643..20530)
                     /locus_tag="PC465_002144"
     CDS             complement(19643..20530)
                     /locus_tag="PC465_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2649438.1"
                     /translation="MAIYLEMPKLIHEFPFRTLSNEGEVLTTPHWHKEIEILLITEGV
                     VNLFINDKPMQLKKGEIVIIKGGDIHYILPSPGSERLVFQFDISFFNDLILLNEEKES
                     LINLFSSIKKCSRDWSAKIRKSVFDILIDIYNEDLYKIEGYSYAIKGKMYNLIPILYR
                     QIPREIEENTVEYEINSKEILERLNNIFKYVEKNYKQPIKLEDVSYEVGFSVYYFTKF
                     FKKNTGKTFITFLNEYRLEKAKWILLNNNISIVDLVEEVGFGSTKTFYRVFKEKIGVS
                     PLEFKKRYNSLEKKGSVSK"
     gene            complement(20630..21079)
                     /locus_tag="PC465_002145"
     CDS             complement(20630..21079)
                     /locus_tag="PC465_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2649439.1"
                     /translation="MEIREILTEESIILDLKSTTKEGIIQELVDKLYDTGSITLKSKF
                     IKALKHREKIGSTSIGYQMAMPHGKTKYVKKASVVIGKSKKGVDWPSIDGLPVKVIIM
                     FAMPQSGGNEDMILISKIAYILGGKNIGERLLNAHTKKEILDIFYEV"
     gene            complement(21069..22976)
                     /locus_tag="PC465_002146"
     CDS             complement(21069..22976)
                     /locus_tag="PC465_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2649440.1"
                     /translation="MLVSRQIEFLKLILNENKYRPIKYFKDKLNVSDKTLQKDLKMIE
                     KYLETFNIKIDIKRGYGILIEDLAKKNIDLINSLNIQSKENKSLSVEQRRMEILKYLL
                     LNSNNITSINQLADKYYVSKTSIVNDFKYIEAWIKEYNLKLNKTLEGTKIIGKEVDIR
                     KSIAKMMDDLLDENYEQHDISELTRLDSATFSALINLFDIDSIIFVETIITELEYNLG
                     YTINQPYYINLITHILICLKRIEEGNQIESQKEREISVDNLDELVYKNVTTLIDKIEN
                     RYRVKITKDELMYIYIFLVSSGFSSENNSSYNDESDRLSESEKVSSIMIENMSQFLNI
                     NLKNDDLLQKSLASHVRPMLNRLRYDIQIKNPLLGEIQERFSDVLGLCMMTINIMTEY
                     DNLKNISIDEVSYLATYFQAAIERNMSSKRVIVVCHTGYGTSQLLAARLKREFPEWTI
                     VDIVPMHQLSKRNLDDVDFVISTVNLDLKDKLHIVVSVLLMENDINNIKNALLSKPKK
                     SMNLDTNLLGMYLEDNIYFNFDVAQMESLIGVNLGSKYESISLGKDLNIYIHKQSKLN
                     KGIMNINNVTRTIDIYLEISNQSFLKNILMEISNLYRQKNYINYIIDCKSKEDIKILF
                     KNNLLEKTNGN"
     gene            complement(23245..25140)
                     /locus_tag="PC465_002147"
     CDS             complement(23245..25140)
                     /locus_tag="PC465_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2649441.1"
                     /translation="MIGKILRSDCIVLDKQLQTKKDVINYMANHLYHGNYINNKEKFI
                     ADINKREKESSTNMGNLIAIPHAKSNVVNQPVMMYLRTDREITDNDGQKLRSFFMIAV
                     PESGSDEHLKIISKLATYLMEENFLKHLLSAETPYEILSIFNNKAAESGDFSNNQNKG
                     LIVGITGCPTGIAHTFMAKKALEEAGQELGYEVKIETHGAIGVENKLTKEDIKRAEYV
                     IIACDKEVQLSRFIGKKVLQKKVVDAKNVSLAKNLIINAENGMAKEIKPGGKTLEDSK
                     EMLQGSEKKGVYKHLMSGVSEMIPFVVIGGIGIAIAFMFGIFASDPTHETYNPIAGFF
                     GQLGGDSAFKLFIPILAGFIAKSIAGRQGFAPAMIAGFMAVIGGSGFIGGMVAGFATG
                     YIALGVMKITENLPDVLKGVNAVLICPLLIAFTSGAIMFFVVNTPASWLNEALQSWLQ
                     SMSGTNKVLLGAILAGMMASDMGGPINKTASAFGLAMFSSNIFEPSAALMVGGMVPPL
                     AISLAMLIFKNKFTKEERKSSLPTAIMGASFITEGAIPFAAADPLRMIPANIIGSCIG
                     GAICMSLDITLMAPHGGIFVIPFACSAPVAYIACILIGTVITALIIGVTKPTIRSENS
                     EVELLGA"
     gene            complement(25176..26054)
                     /locus_tag="PC465_002148"
     CDS             complement(25176..26054)
                     /locus_tag="PC465_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HDF2649442.1"
                     /translation="MLINMKEMLKVAQENQFAVPAFNIGSGQILKAVVQSANEKNAPV
                     ILAIHPNELSFLGDSFVASCIEEANKSKVPMVIHLDHGENKEQILKAIRCGFTSVMID
                     GSHLPYEENVAISREIVEIAKGLNVSVEGELGTIGTTGTSSEGGTDEIIYTDSKLAKD
                     FVEKTGVETLAIAIGTAHGIYPKGFKPELKLDLLKEIREVVDIPLVLHGGSSNPDEEI
                     AQAVKLGVCKINISSDVKSAYYKKCRELLEQNPSLYEPDTIYPPCIKAAREVIEFKMN
                     LFNAIDKLKCFYKNKN"
     gene            complement(26597..26767)
                     /locus_tag="PC465_002149"
     CDS             complement(26597..26767)
                     /locus_tag="PC465_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649443.1"
                     /translation="MSALLYGVCNKPISVSIVINMQEFKIGVSMAYGVLVIGICYIAL
                     GIIFKLDRKRFT"
     gene            complement(27276..27515)
                     /locus_tag="PC465_002150"
     CDS             complement(27276..27515)
                     /locus_tag="PC465_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2649444.1"
                     /translation="MSKDYGYPSFELICRASSGDEVAIREILKFYDAYISKLCLRPFY
                     HCESGKIIMQVDEELKGEVYTDMMKAILKFEIRVK"
     gene            complement(27521..27940)
                     /locus_tag="PC465_002151"
     CDS             complement(27521..27940)
                     /locus_tag="PC465_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009269612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase subunit sigma-70"
                     /protein_id="HDF2649445.1"
                     /translation="MNTSSFKDIVRLQFNSLMMIIIKGRVKYHKKQIMKRSKNEVLFC
                     EMSETERLEQGTVDTYIYDYVSFQVFHFTICVTDEKLATALNMLSKKQRSTILLRYFQ
                     GMNDREISELYHVSRSAIFSRRSRGLKKLKMLLSERK"
     gene            complement(28123..28590)
                     /locus_tag="PC465_002152"
     CDS             complement(28123..28590)
                     /locus_tag="PC465_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649446.1"
                     /translation="MATEKKVYKVINEAGLKALENKCIIVKYAPHNLSAKILEFFNSE
                     FYVLQLCEHEIVLIPFNLMTLNMTLKKEELLVIPYSRIKSIEISEDLLNYIISITTDT
                     DIIRLSTQQKELSNLRTSGSLTSKKAGITLENWHKDNLDITLEALKKIDTNSN"
     gene            complement(29404..30453)
                     /gene="cfr(B)"
                     /locus_tag="PC465_002153"
     CDS             complement(29404..30453)
                     /gene="cfr(B)"
                     /locus_tag="PC465_002153"
                     /EC_number="2.1.1.224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(8))-methyltransferase
                     Cfr(B)"
                     /protein_id="HDF2649447.1"
                     /translation="MQQKNKYIRIQEFLKQNKFPNYRMKQITNAIFPGRINNFNEITV
                     LPKSLRDMLIEEFGESILNIVPLKAQQSTQVSKVLFGISGDEKIETVNMKYKAGWESF
                     CISSQCGCNFGCKFCATGDIGLKRNLTSDEITDQILYFHLQGHSIDSISFMGMGEALA
                     NVQVFDALNVLTDPALFALSPRRLSISTIGIIPNIKKLTQNYPQVNLTFSLHSPFNEQ
                     RSELMPINERYPLSDVMDTLDEHIRVTSRKVYIAYIMLHGVNDSIEHAKEVVNLLRGR
                     YRSGNLYHVNIIRYNPTVSSRMRFEEANEKCLVNFYKELKSAGIKVTIRSQFGIDIDA
                     ACGQLYGNYQKTNSQ"
     gene            complement(30791..31132)
                     /locus_tag="PC465_002154"
     CDS             complement(30791..31132)
                     /locus_tag="PC465_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009269613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649448.1"
                     /translation="MLSLYEFLWNVFNSKTVLIIGAWASLSLTLILIVMFVRKQNRDE
                     RGWKIKGKASAIAFIYFIIMANLLAKAVGAMVPDTLEVGYVFCANVIQWLYDTMIFIE
                     IIAILILNKIE"
     gene            complement(31135..31356)
                     /locus_tag="PC465_002155"
     CDS             complement(31135..31356)
                     /locus_tag="PC465_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2649449.1"
                     /translation="MAKKNKYSFDSKIHVYRATKRMSQQELADLVGVSRQTIIQLERN
                     RYNPSMLLAYSIAKVFDVTIEDLFDFRED"
     gene            complement(31589..32209)
                     /locus_tag="PC465_002156"
     CDS             complement(31589..32209)
                     /locus_tag="PC465_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005341381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2649450.1"
                     /translation="MKINFLGNNIQTIRKYRGMKQQELADKIGINMQSLSKIERGLNY
                     PAYDTLEKIMEVLDVTPNELLSGEWKYINQAEKEVCQFLRAEERLNTELKHGHYDNFF
                     DSEEEWLEYELEKLREYITDYINGNNIQAGDLYPIKEFIQHLKFQRLLDRYDDLYSMD
                     MFGESIEGHKYKTPFQFVKRINPNSKEDMELLREVLGNNHFDDEDE"
     gene            32743..33885
                     /locus_tag="PC465_002157"
     CDS             32743..33885
                     /locus_tag="PC465_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF2649451.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHLSRYSINRFENGKAN
                     ASRETQNIILRCLNYYVCDKPFYLLVDYLSVRFPTTDALAIIRKVLGMKADYFIHYDY
                     GYYGYKEHYTYGEIKVMVSDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGLIRRFDLAVNDMCGLLDIPTLSEKYKNGGADCRCKNYENVQGGKLSGKNRDLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDTKAVQAVEELLLTYNPHG
                     LVFYLITDFVDFPDYPLWEIFTSHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECNHLSEKQEMIVEQMCTDIADVIESEGVFYE"
     gene            33878..34084
                     /locus_tag="PC465_002158"
     CDS             33878..34084
                     /locus_tag="PC465_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDF2649452.1"
                     /translation="MSNAQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEQVIDKLDAI"
     gene            34164..35357
                     /locus_tag="PC465_002159"
     CDS             34164..35357
                     /locus_tag="PC465_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF2649453.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDAFGNTKYVYAWRL
                     TPTDVTPKGKRHDISLREKEEQIKKDLLDGIDSTGKKMTLCQLYAKQNAQRANVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKEKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLNEVIEDDTKGKVALTEGQEQALLSFIKIDNVYHKYYDDVLI
                     LLKTGLRISELCGLTVKDIDFKNEIVHIDHQLLKSKEQGYYIETPKTKSGIRRVPLSE
                     ETIKAFQRVIKSRPKTKPTQVDGHSDFVFINHKGKPKVAIDYSTLFVRMVKKYNKHHK
                     DNPLPHITPHILRHTFCTKMAHRNINPKDLQYIMGHSNISITMDWYAHSSIESAKTEI
                     KRLIA"
     gene            complement(35593..35805)
                     /locus_tag="PC465_002160"
     CDS             complement(35593..35805)
                     /locus_tag="PC465_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2649454.1"
                     /translation="MAILMKTKIKEYREKLLMTQNELAKLVGVRRETIVHLENGKYNP
                     SLKLAMDIAKVFDTTVENLFEFIEEE"
     gene            complement(35806..36222)
                     /locus_tag="PC465_002161"
     CDS             complement(35806..36222)
                     /locus_tag="PC465_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649455.1"
                     /translation="MSKSETGVRSKLILELIVITYFFIAVLATKYIFKGPSTASLPGL
                     SWLIVFGCYSIYNKKYNDLVDESSEFILSKVNKIAIKIMIYSIVIISIFFATPYTSNI
                     NISNLDTGIILIAVLFIQSLSKLVLYIYFDKRGICN"
     gene            complement(36290..36703)
                     /locus_tag="PC465_002162"
     CDS             complement(36290..36703)
                     /locus_tag="PC465_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649456.1"
                     /translation="MSKSELGVKTNLVSELLMISYFFIDSLLKKFIFKEGNLCITFII
                     LFAFWACDFMYNKKYNDLVDEASKLMLLKVDHIASKIMLYSILLISVFFSANYTRGLD
                     ISNLDIGVILLAILFIQSLSKLILYIHFDRKGICN"
     gene            complement(37537..38166)
                     /locus_tag="PC465_002163"
     CDS             complement(37537..38166)
                     /locus_tag="PC465_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HDF2649457.1"
                     /translation="MKNRKVYMYVFDTMSDWEVAYLTAELNTGRYFKKGLKPLKVITV
                     GIDKNPIITMGGLRVLPEITVDEFNMESKDLLILPGGNTWLSMNHEIILEKVKEALIQ
                     DSIVAAICGATLGLAKKGLLDFRNHTSNDLEFLKMVIPNYSGEKYYKTESVVSDENLV
                     TASGIAPLEFTFQVLKLLDVFESEALNSWLNLYKTHDSKYFFELMNCNK"
     gene            complement(38245..39207)
                     /locus_tag="PC465_002164"
     CDS             complement(38245..39207)
                     /locus_tag="PC465_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017561613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HDF2649458.1"
                     /translation="MAKIDNMMSILWMLNSDKKITAKQIAEKLEINIRTVYRYIDVLS
                     ASGVPIISDTGHNGGYSLLNNFTKAPLFFDIEEQKSLLHAALFAKKEGYFLDEALDKS
                     ILKLKMYSNQKQEDILTNHLRALEVIKPIGKVSIESVLKKLENSILKELSVEINYHAG
                     RKAKSKYRIINPYGIVHWNNNWYVVAFCNMRNEVRSFRVDRISEIIETSNTFNRPTEF
                     SASEFFIKGIIPEIKDEQNIIQLVVEGSIDSLDSLSQHWFLGHYLKERTPNKIIFMLE
                     EEVICKYIPNILLPYRKTIQVIEPLSLRKKIIEDLLELIDYYQI"
     gene            complement(39969..>40577)
                     /locus_tag="PC465_002165"
     CDS             complement(39969..>40577)
                     /locus_tag="PC465_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649459.1"
                     /translation="DSGNGGNSKPDSGSGGNSKPDPDNGGNSKPDPDNGGNGKPDPDN
                     GGNSKPDPDNGGNSKPDPDNGGNSKPDIDNGGNSKPDIDTDGDGKPDINIDTDGDGKP
                     DINIDTDGDGKPDINIDTDGDGKPDVNIDIDGDGKPDVNIDIDGDGKPDINIDTDESL
                     DSNVGQNVQTGDQSNIMLDLALMFISLFFLIKNLTNKYLRRK"
BASE COUNT        13374 a         7030 c         4635 g        15538 t
ORIGIN      
        1 tcaaaaaaat tttaaaaaac tattgacatc taatagccag tcacttctac aacctagaat
       61 tgttctatta tttattctct ttcaatttct atacttaaag attttccaga tttatcgctt
      121 tgaaaatttt cataatacca aaaatagaaa ggcttttcac aaagttcaaa ataaataatt
      181 tcatcgggtt ttttattttc tatttttgca ttgtaaatat cttcatcatg tacaaatcca
      241 tataaaaagc gactattgtc tggactgata tttaaatctt gtaagctatc acttaatgct
      301 aactgtgatt ttagtaacga catcgtatct ttgtcatacg ggcggtcttt ctttataacc
      361 tcatgtacac ttgtaatata agcatatctc tttttaccat ctatttcctt aattttgaat
      421 tttgaaaatg tcaaacttga ctctatatcg tttttttctg atatatacaa aacactttta
      481 tagttttcgt tttcaaactc ctttataatc ttatcaatat gtgctttata ttcttcgcct
      541 tgttcaaact caatagaggc acttaacaga gcatcctgta ttgagtttgc ataattttca
      601 tcagaaagta aactttcttt tgagtttaaa tcttctattg gataatattt tgttatttct
      661 gccggaacat atttatcgtt tatttctgtt ctttgtatta aactatttcc acctgttatt
      721 tgacctaaat atccaagccc tagaaaaaca ctaaacacaa aaataattat tcccaatatt
      781 atccaaatta ccttcttttg tttagtcata agattaagcc ctctcaattt attgattgtt
      841 aaatacaaat ttatatgttt ctctgtattc acattatacc attttccact acctgctaca
      901 atacttcaaa atcttaagac tacttttttc tgcttttgaa aagctacttt accgtccata
      961 atttgtaaag ggtgctaagc attgcttacg caacaagccc ttgacaaatc atatcccaat
     1021 aagtttagag taatcaagca gaaataaaat agcctgttgt tttaagccaa tgaaaaagag
     1081 ataccaacac atttatgtag tatcgctaac ttaatagcat tattctttta ttcgcaagca
     1141 ggtaaacaca ggttattcct taatatcctt ttgtttggga aactccactt tcccattttg
     1201 ctattgattg tctagaaaca ttaagttttt cagctaattc ttcttgtgta tactggttga
     1261 tttttcttag actttttaaa ttctcattaa tcatattttt catacctcct atgtttataa
     1321 tattggattt attatttaaa ttctatcaac taatcttaac attcatatat atatttatat
     1381 acttttatta tataaattta ttattcaggt aacatatttc cttaagttat cgtaaacaaa
     1441 aaaacaagca caaatctact aactgttgtt aaagtattta agttaaggtc atttacatta
     1501 tcaaatattt ctacaccttt aaaataacct ttatatttat aatctttcat aagcaaatta
     1561 ttatcccttc tcatatacaa gtccagttga tgtcttgttg ctaaatttaa tggtaatcaa
     1621 attctttacc aataagtata aaaattacta atgtgttata attttcttaa ctactaaatt
     1681 ttacatacat ttgaatagaa tatatcaata aattactata ataaataaaa aattaagagt
     1741 taaaataaaa aatagttagg gagatattat tatgatttta tattttagcg gaactggtaa
     1801 tagccgatat gtggctcgta aaattgcaca agaattaaat gatgaactga tatcactaaa
     1861 tcaacttata aaagaggaaa aaacagatga attaatatca gcagataaac cattcatatt
     1921 tgtatgtcct acttatgcat ggagattgcc aatagtggtt acggatttta taaaagaaac
     1981 aaaatttcta ggaagcaaca gagtttactt tgtaatgact tgtggtggag atacagcaaa
     2041 atccataaac tatattcaaa aactatgtaa atataaggaa tggcaattaa aaggtatggc
     2101 agaaattaaa atgccagaga attatatagc tttattttct acaacagaca aagaaacatc
     2161 aaaacaaatg attaaagaag cagataaaca aatatatagg attatttctg atatacgcaa
     2221 tgaaaatgaa tttgaaacta ttactcctag tggcttagga ggtacaatta aaagtggtat
     2281 aataaataca gttttttata agacaattat tagtgccaaa ggatttcatt atactgataa
     2341 atgcattggc tgtggaaaat gtgtagagct atgtccttta aataatatta atttaaaaaa
     2401 caaaaaacca gtttggaaaa ataactgtac tcattgtatg gcatgtattt gtggttgccc
     2461 cactgaagct attgagtata aaaataaaac tcaaaacaga gaaagatact atttagaata
     2521 atatattctt aatatttaaa ccattataaa atgaactata cccattgttt tatacagttt
     2581 tacatatttt aactgtctcc taagatgggt atagttcaaa agatagtgtc tcaaagtgaa
     2641 ctttttagtt cctaaatcaa tcttttttgt attaaatcaa gtataattta atcacctttt
     2701 cttatatcat tttcactaat atgttgtatt ccaacaaata taagatttat tagctctgtt
     2761 agtgacttcc attgtgattt ttttgaatca agataataat aatttttcgt tccttctcta
     2821 cgcaaattaa caatctctgc ttcttttaat atcttaagat gatgagatac agcaggacga
     2881 gaaagatgtg ttttttttgt gatttctccc actcgtatac cattaaaatc actctctaag
     2941 agagcaatta aaatcaattg tctagtctca tcacccatag cagagatagc tttgcgacat
     3001 tctttaaatt tagacgttat ttcttgcatt ctttgttgac attctttttc cataaaatcc
     3061 accctctctt ataagtatct aacagttgct acttctttct gtgcagtacg tctatattta
     3121 acatctgggt atccaattac taatgttgta agaacatgat tactgcgttt tagacctaaa
     3181 agctttttta actttggcga attatttgct acatctgaaa aatatccact aaataaaaca
     3241 cctaggccat aagactctgc cattaatgcc atatttgatg ctgcaagtga accactaatc
     3301 ttatcttttg taattatcat tattgcaata ggagcatgct taaagaaaaa gttatcgtca
     3361 atctcaactt cttttgaata tttaatagct atatttgcaa taggttttat ttttctaaaa
     3421 aatttcactg cttcgttttc ataaattgac tttttattgt ctaaaacaat atatgataca
     3481 tcttgtgaat ttttagcact aggggtatac ctacctgcct caataatttg ctttacaatt
     3541 tctgaagaaa cttctttatc tttaaattta cgtatacttc ttctagattt aattgccatt
     3601 agtaattcat ctgaatctag ctttggctta tttgtaagtt ctataggagg ttcatcaaat
     3661 cctgtcaagg caatagcttt tgtgggacat attgctgcac aatgtccaca cattagacaa
     3721 tcttgttttt taattactga ctttttattt tctataatta tattgtttac tggacaatca
     3781 tttttacaaa gcccacatcc aatgcaaagt tctttgtcaa cttctattat atgttggtat
     3841 ttcatattca ttcatctacc tttcgtttat tagtttaaac tattataaca cgtagacatt
     3901 ttttatattc attggtaaag aatttgatta ccattaaatt tttaatttct ctattaaata
     3961 aatttttcat agaattttaa aatatcatag tttatacata ataaaaaaga caagcttaaa
     4021 acctaagctt gcctttttca tcttttatta caaagtaaat tgcacttact tcccatactt
     4081 cttaacaatt ttattttcta aaattttatt tgtgaatcat actattgcat caatacaatg
     4141 taaaataatt ctatattgat tttctatagt taaaaaagtt aaaaattata cttattatta
     4201 atttttatac tcttcttatt taatacaaat ttcttattta acatagattt cttgtctaat
     4261 ataaatcttc accatttgaa gcaattactt tcttatacca ttcaaaactt ttctttttca
     4321 ttcttcttag acttccatta ccactattgt ctctatctac atatataaat ccataacgct
     4381 tttccatttc acctgtacca gcacttacta aatcaatagg tgcccatgta gtataaccta
     4441 ataaatcgac cccatctata gaaactgcat catgcatagc ttttatatgt tctcttatat
     4501 aatcaattct gtaatcatct tctacataac cattttcatc agctatatct ttagcaccta
     4561 atccattttc tacaataaat agtggctttt catatctatc atatacatga tttagtgtaa
     4621 ttctcaaacc taatgggtca attggccatc cccattgact gtatgaaaga tatggatttt
     4681 tagcagatat aaatatgttt ccttcagcca tatcatctgc attttcatcg gttctaacac
     4741 aacggctatt gtaatatgaa aatgaaataa aatctactgt atatttattc aataattcaa
     4801 tatcaccagg ttccatttct ggtgtaatac ctttttgctc catatacttt aacgcatagt
     4861 taggatattt acctttagat tgtacatcca caaagaagta attttctcta tctaactttg
     4921 tagcttccca tacatcatta ggattacaac tataaggata tacacttcca gctgcaaaca
     4981 tacatccaat taagttattt gaatcaactt catgtgctat tttagttgca attgcactag
     5041 ctacaagctc atgatgggca gcttgatatt ttatcttttc aacatcttca ccttcttcaa
     5101 agcaaatacc agcacccata aatggagcat gtaaaatcat atttatttca ttgaaagtta
     5161 gccagtactt cactaatcct ttatatcttc taaagataac attgcataat ttctcataga
     5221 aacctatcat ttttcgatta cgccatgcac catacttttt aactaaatgc attggacaat
     5281 caaagtgtgt aatagtgact aaaggctcta ttttatattt tttacactcc ttaaatatat
     5341 tttcataaaa ttgaagtccc ttttcatttg gtgtttcttc atcacctttt ggaaatattc
     5401 gactccatgc aatgctcatt ctatatactt taaatcccat ttcagcaaat aactttatat
     5461 cttctttata attatgatac atatcaatac cagttttagc tggataataa tgctcatcat
     5521 caaaatcaaa catttttagt ttccctgtaa taactgctgt tctatctttt cctgttggac
     5581 atacatctac atttgccaat cctctttcgt cttcattgta tccaccttca cattgattgg
     5641 ccgcagtagc tcctccccat aaaaaatcat tcttaaaact catagtcaaa gcctcctaaa
     5701 attataacca aagcactaga ttatgctaat acctcaatct ttactaaaat aagactgtaa
     5761 ttagattgtc ttctaattca atatttttac tttctgtttc tactacatct aaaaattgtg
     5821 atgaatttgt aataacaatt ggagttacag tactataccc caactctttt attgcatcaa
     5881 catcaaagtt taatatagtt tgaccttttg taattctatc accttgtttt atacatgcct
     5941 caaaacctct tccctctaat tgaatagtat ttaatccaat atgaataagc acttcaacac
     6001 ctgtatcaga aagaatccct atagcatgta gactaggaaa taaggttgta actaccccat
     6061 ctactggagc aactactttt ccatcactag gtattattgc caccccttga cctagtacac
     6121 cagatgcaaa tgctgcatcc tctatatcac ttaattttaa tacttcacct tttataggac
     6181 ttgttactat ttctctttct aatttagtag acttgacttc ttttatttct tctttaccct
     6241 tatttcttac ttttttagac tcttctactt tctcatcttt atataaaatc atagttaata
     6301 caaaagctac gaccattgat atagctatac cagaaagagc tactattaag ttacccattc
     6361 ccccatctgg ttcaatcatt gctggaagtt caaatattcc cattcctcca gttataaatt
     6421 ttctaagatt aaagaatcca tagaaagcgc ctccaatacc actagcaata caacttatta
     6481 taaatggttt ctttaaaggc aataatattc cataaattgc tggctctgta actccaaata
     6541 taccagatat aaagtttggt attgccatct cttttagttt tttatcttta gtcttgaaaa
     6601 atattgccaa cacaactgcc gaacttgcaa atgtacaggc aaagaatggc atcataacat
     6661 tatcatatcc taaagtcata acattgttta tatatacagg aataaatccc cagtgcatac
     6721 caaaaataac aagaatttgc caagtaaatc ctactatagc acctgccaat agtggactaa
     6781 aatctcttat tgaaattaca atttgtgaaa taagtgtaga accaaatgtt gctataggac
     6841 ctataactat aagtgcaaca ggcactgtta ttaataatgt aagcattggc acaaagaaaa
     6901 acttaactaa atctggaaca cacttattaa ataatttttc acacctagaa gcaaaataca
     6961 ctataaatat aattggtacg actgttccag tataatcaat tgatacaatt ggtagtccaa
     7021 aaaaatcaat atatactggt gatgcaaaca ttgttccttt aaataaagtg tacatcacat
     7081 ctgctcctac tgatatactg ctaccttgta tagcaggata acatactgca gctcctagtg
     7141 ctaatcccaa cattggtttt aatccaaact tcttagctga agtatatcct aagaacaaag
     7201 gaaggaatgt aaataatgca tctcccgctg catttattac catataacca ccagatacat
     7261 cactatataa tcccattgct acaaataatg cattaaatcc tttcaacata ccacaagctg
     7321 ccattattcc taacactggc tgaaaaattc ctgatattat atctatacct ttatctagta
     7381 tattacctga ttttttagtt tctgaacttg tacttgaatc atctaaacca attatttcaa
     7441 ctacatcttt atagacagct tcaacatgat ttcctataac tacttgatat tgtcctccac
     7501 ttttcattac agtaacaata ccttccatgt tttttaatac attgtcattt gctatacttt
     7561 catcttttaa agtaaaacgt aatcttgtaa tacagtgtac taatccacta atattttctt
     7621 ttccaccaac attgtttact atctcttgtg ctaattgttt gtattttccc atttttctcc
     7681 tccatatttc gtttaaatta attttttgaa atttgaaggt ttggccaact caatgttacc
     7741 atccaaccat aaatataatt ttgttagtat cactcctttc aatcattctt aatatactgc
     7801 tgaaaaatta tttcacttac atatttgagt ctttaactac tttagctaaa tgtattgtta
     7861 aatatataag ttcatcatct gttaatatgt agttatattg ttttttaatg aaatttttaa
     7921 ttttaactac acattcaaac tctttattat atttagattt aataatgctt agtaattctt
     7981 tgtctgtctc accttcatgt gcactatcta aaagcaatct ttgcgcaaaa aactttaaat
     8041 gcattataaa tctataataa aacactgatt cttcatgaaa ttctatccta aaatgatacc
     8101 taactatgct aagtacttct tgtattaact tcgtaatatc agatgccaaa gtatgacctt
     8161 cacttaactg agcattcact atatgaaagg ctataaatcc agcctcatct tctggtaatt
     8221 ttatacctgt tttgttttca ataatatcta gtgctttcat tccaatttca aactcttctt
     8281 tataaaatct tttaatttcc caaaggattg cattttttac atttattcct tctttcattc
     8341 tttgaattgc agaatatgta tggtcactta aggatatgta aatactttca tttagcttct
     8401 tgtttaactt tatttgtgcg tattctataa tttcacttga taatttcatg tgttctatag
     8461 gaatattatt gagtaattct tgtagtttgt ttgatatttc tttatttgat attctaaata
     8521 ctttatttac tttagtttta tctattagat tgccttttga tttttgataa ccaattcctt
     8581 tacccataac gataacttct tcatcattat catctaatgt gattataaca ttattgttta
     8641 atatcttatt aattatcatg attatcctcc ttttaagcat aaaaaaagct tatccataat
     8701 aatgggcata ctccttccta ggatactgct attattaatg aataagctta gcttgtcctt
     8761 aaacaattac tacctaattc caattaatat gataaaacat cagacatatt ttgtcaactt
     8821 tttatttcca tatacttcat caatcttttg tgttgctttt tgtcagttat aataattatt
     8881 cttattaata ttaatttaat agagtccatt tttaatagtt ttattataat ttttaaaatc
     8941 aacaacatta aatcctttat ctattagaag attatatgtt gttatatgtt ttaaattata
     9001 ttttctttct cacctctaaa ctattctcta tctcttattt atttctgtaa taaaaaacga
     9061 ccttctatag taatttaagc tctcacaata ggttgttttt cgatttataa attcaattat
     9121 taacctcttc atttgactta aaatctatac tagatttgtc tcaataaaaa atttataagt
     9181 ctaatttaat atttctttga gccaatataa atataaaaca atttatagac aatactacta
     9241 aaaattctat taaaatcaat aaataattaa tattataagc tctctgcaac aatgaaatta
     9301 gtaagaatct aaatagttca taaaaaattg ctataagagt actttggata attgatacaa
     9361 ttatcatttc taataaacct atttttatca attttcgttt actcattcct actctataca
     9421 taatttgata atctagtact ctccttataa aaataattat ttgagatgtt agtattagaa
     9481 gtatacttga caatgacaca gcaaatataa tattcaaaag taatgacttt tgatcatcaa
     9541 catatgtttt catagaataa gcaaaatcat tatagtcttc taaattagca tatttatcat
     9601 tatgtaataa tttactaagt aaagtgttat ctaacttttc tttaaaaaaa tatattactg
     9661 gttgattttt agataaatca agggttttag gtgaaatatt ttcatttata tttatatatc
     9721 ctaaatctac acctttgttc aatgattttg gacttaaaaa tcctattact ttaaagtcta
     9781 tcttctttcc attaattctt aactttacag tatcgcctag tttataatct attaagtatc
     9841 tatgaagata attatttata attatactat tttctttatc attttctttg aaccagtttc
     9901 catactctaa atcacttttt aatattgtct gtttagtatt gaataaatca acacttaagt
     9961 catttaaatc attcattaca tcttttctat tctcatatgg aattttttca atataatcat
    10021 taacagaaat attatttact gactctatac tatctatttt aattggataa tattgaaaat
    10081 aatctatatc attttcgata agttttttat ctgtaattaa ttttccttct aaagttgttt
    10141 gatatacaat tgaatttttt atactattat caacttcata attgctaaac atagcaaagg
    10201 ttatttcaga tatcataaac aacaacaaaa caaatattat tgttattgtt aatagactag
    10261 agctaaaagc attggtttta caatcattat taagatatat aaaagtaatc gagtattttc
    10321 ccttaataat ttttttaatt aaacatacca tttttaataa tgcatatatc aaactgtata
    10381 ccaataaatc tagtagtatt aatcctaaaa taaaaaaaat acctagaaag gacttcacat
    10441 atattgtaaa agaaatactt gttaaaaata ttacaagaat tatatctgga ataaagttaa
    10501 atttatatga agacaacata ctattatctc tatttattcc ttcataatgt atttttttaa
    10561 caaaacttat aggaattaat gagaatattg atgtttcaat tattataata actattgaaa
    10621 tgaaaatatt tttgataata ctcaaaatag aaatattaaa tagattaata tgttgtaagt
    10681 taatatagaa tatagttata ggaatcccca aaataatacc tattataatc ccctttatag
    10741 taattgacat aagttcagta aatactagaa aagataaact tcttttttta attcctaaag
    10801 ccttaaaagt tgaaaaatca tttattcgat ttaaaataaa tacaataaat gtagaacata
    10861 gacaaattcc agtgcttaat aatgaaatag ctccaattaa atttattgaa tctaattgca
    10921 tagatattct ctttattatt gactgttcta gttcatcagt tgttctaact tcaaaatggt
    10981 ttttaaatac attttttatt tcatttttaa tatttttcac attttctttg tttattatat
    11041 ttatataagc tacattatat ttagtttcat taggcaaata tacataactt tctccaacta
    11101 cctcttggcc aacctctgct tctttttgag ctgtacttaa tgaaaacctt tttggtatta
    11161 tatcactaac tttaaaatat gtatcatcat aaactgaaga atgtagtttt aaaaacactt
    11221 tatctcctat atttacattt aatttattag ctgttttttg ggataaaact atatcatttt
    11281 catttcttaa ttttaaatat gtattttgca tttttatatt atttactaca gtcaattcag
    11341 tactttcaat cataccattt gacaatatat ttgtattcat actacttccc aactgaaaat
    11401 caatagattc tttacctttt aattcttcta acttatctat ttgttcactt gtaaagtagt
    11461 atttattata ttctatattt tgtattttta tatctccacc atttgttata gccatatttc
    11521 tcttaacttc acttgaatat gtatccgtta acactcttgt aaaaagtaat attgctgtgg
    11581 caaatacaat agatattata caagagattt ttaataattt attattcttc aaactattct
    11641 tactatatat tttataaact tcatgaaata tcaatgtatc accacctatt ttataatagt
    11701 tccatcttta atacttataa tcctatcact atattctgcc atttgaatat catgagtaac
    11761 cattactatt gtagtaccat attcattgtt tatattctta aacaatttca ttatagcatg
    11821 actattagta ctatctaatg atccagttgg ttcatcagca aagagtatat ttggagaaca
    11881 aactagagct cttgaaatag caactctttg cttctcacca cctgataatt gtttaatatt
    11941 attttttgtt tttgatgtca acccaacctt tttaatcatc ttatctacta ttttataatc
    12001 tttattatca gaaaaaatca atggcaattt tatattttct tcaacagaca ttgatgtaat
    12061 taagttaaat gattgaaata caatccctat ctttctattt ctatattcag caagttcatc
    12121 atcagttaat ttcgataaat tctcaccaca aactttcacg tttccagtat agtttttatc
    12181 aagaccactt aatatactta ttagagagct tttcccacta ccactagcac ccattataga
    12241 aacaaattct ccttcttcta tgtataaatc tatattcctt agtatagtaa gttctgtgtt
    12301 taacaagtct acaactttag ataagtttga aacttcaatt atcatttttt tcataccatt
    12361 atttcctttc atacaaaact tttaagattg attattaatt aaaacagagt atataggaca
    12421 caaaatatta gagaaactta tacaagcaag cttttttgag aatgatatat tttctaaaac
    12481 tgtacaaatc ttaataggtc attatatttc ttattataca taagattgct tgaccaaaag
    12541 ttagtaaaat tataaaaaat aaactttttc aatgataaat ctaaaaaata taatatcatc
    12601 aataattcgg aagtgggatt taatttaata ctaagtttta gcttagatat acagaatctc
    12661 tccccaaaat ttatatattt ataacacttt atgttataaa tatatgactc tttcaaataa
    12721 atttcaacag aatattgcga atacttgata tcatcttata agtataattt ataaaaaatt
    12781 tcatgataaa tatttaagaa ttacagatac tattataaaa ctactttttt attacatttt
    12841 atagaactct ccacataaaa aatgcttata acttatggca taaaatgatt ctttaataaa
    12901 cattacaata caaggctaaa ctattctatt aatcatatta tttattaatc accatcctaa
    12961 tggactaata acttttacat gtacaatttt atacattata aatcctatag tacacccaag
    13021 agaccatctt cctgtagtag gaatataggt atcaaatttc ttctccaaaa taaaaaatat
    13081 gccaaacctt aacaaaacat atttttatat attttactaa agtttgacta tttaagaatc
    13141 gtatttttta aagttttaaa ttgagtttat cttaattatt atataactat tatttactaa
    13201 gttttatagg ttaatcactt ttattataaa tatttatcat gaattttttt atctcatact
    13261 atttaacaca cttccttaat ttacctatac cttccttaac atttttttca actccaaaaa
    13321 catatgtcat aataaatgga gcaaccaatg ctataaatat aactataagt ccatttacta
    13381 tatttgaaat ccccttttcc cctgataatc caagtactgc cattatacta ttttgtggaa
    13441 catataaagt cacatgagta attcctgcaa ataaccctgc gattcctgct cctatagatg
    13501 ctaacatagc aggtttttta agtttcaatg taactccata aagagctggt tcagttatac
    13561 ccataatagc tgatatccat gcagctgatg ctaactgttt catcttacta tctttgcttc
    13621 ttaatgctac agctaatgtc gcgccacctt gcgctaaatt agcacaaact tgagatatta
    13681 atattagcga ttcttgtcct gtagttgcaa atgctgatat gaatatagga gtcaatgcat
    13741 gatgcatccc tgtcataacg ataaatggca ttgcagctgc taataaacaa accattataa
    13801 atcctaacct tccttgtagt aaatttatta tactagctaa tccctctcct aagaaatttc
    13861 ctattggtcc aattactatt aatgctattg gcgcacttat taataatact aaagttggat
    13921 ttaaaattgt ttttaacatg ctaggtgtta atttatcaat gaatttttct atatatgaca
    13981 tcatccatac tgttaaaagt gcagggataa cagatgctgc atatataaca ccttgaattg
    14041 gtactcctat aaatgatata gggtccccac ttgataccca tgcagagaaa tttggatgta
    14101 aaaacacacc tactactata actgctattg atgtattaac attaaatttt ttagctgcat
    14161 ttattgcaag tattataggc ataaagtaaa atgctacatc tcctattata tctaatactc
    14221 tatatgtact tgaatttgat gatagccaat taaaagtggt gcaaagagat aatataactt
    14281 ttatcatccc agatgctgta agggctggta tcataggtgt catacaacca attattgtat
    14341 ctattatatt atttaaaata ctattttttt tatttttatt ttttatatcg cttttaatat
    14401 ctcctgtggt atttatcccc ttatttatta ttgcattaaa tacaacacct acctcattac
    14461 ctattatgac ctgatattga gttgaagttg agtttactcc aactacctta tctatagatt
    14521 ttaatttatc tgcattgact ttcttttcat cttttaagat gaaccttaat cgtgtcatac
    14581 aatgagttaa gtcaattata ttatcctttc ctccaagtcc atcaattatc aattgagcta
    14641 cttcttcata tttattcttc ataccttatc ctctctttta aaataatttt taatataatt
    14701 ttaatccaaa ttaatctttt tactccaagc ttgtaatagt gtattgtaat ttaataagct
    14761 agtatcttct acaatatggt catattttcc tagtacttct tttttcccca caccaattga
    14821 tgtcatatta gcagcattta tagctttaat acctgaataa gaatcttcta ttcctacaca
    14881 atcatattgt tttaaattta gaatcttgct cccttcaata aaaatatcag gatatggttt
    14941 tccccttttt aataaagatg gatttactat acaatcaaat tcatctttta ttcccaaaga
    15001 ttctaatatc ctaggtgcat tcttactagc agatgctatt cccaatttca cattattttt
    15061 tttaagttct tttataagct catttatccc tggtaatata tctttatatg ttaatgagtt
    15121 tattaacttt atataaatgt tatttttttc ttcacacacc tttaactttt cctctttagt
    15181 ataactatct actttattag cagataacaa tattttatct aatgattctt ccctgcttat
    15241 gccttttaat ttttcattaa aagtttcatc tatttctata tctagcgatt ttgctatctc
    15301 atgccaagct tcaaaatgat acttagcagt atctgttata actccatcaa gatcaaataa
    15361 gactgctttc atattaatta ctccctttaa aacaattatt aacttctatt atgttctttg
    15421 ataattttat ttctttatta tcatgtaata tggttatatt tctacctttg attaacttat
    15481 aataagattt atattcttct atatttacag aaactaaatt atctctaaat aatatattaa
    15541 atttaatatt tttccagtgt ttaggtatcc ttggttcaaa acttaattta tcatttttta
    15601 ttttcattcc tgcaaatcca tatactaaac tcatccatgt tccacccata ttagcagcat
    15661 gtattccatc acttgtattt ttttgtaggt tattaatatc cattaatgct gtgtccataa
    15721 aatagttata agctttttca tgatttccaa tttcacttgc catcattcca aatattgacc
    15781 ttgacaaaga tgaatcatga gtagttattt tttcatagta ttcaaaatct ctcttctttt
    15841 gttctaagct aaactcatca gggaaaagca acgctgaaag tacagtatct gcttgtttat
    15901 ttacttgata tctatatatt gttaatggat gataatgaag aagtaatgga tatttttctt
    15961 ttggtgtatt tttaaaatcc catactgatt tttctaaaaa tgaatcgtct tgtttgctta
    16021 ttttcttctc ttcatcatat ggtaaataca tattttgagc ggcatttatc cagtttttca
    16081 cttcatattc ttgtaattta acttttctaa atacttcatt tgaaaataaa ttatgcttaa
    16141 atttatctac catctgtact gcatatatta aattatactt agccattaaa ttagtgtagt
    16201 aattattgtt tactattgct gtatattcat ctggtcctgt tactccattt atacagaatt
    16261 tattattttt tgattctata taatctccaa attcaaccca aaatcttgct gtttctataa
    16321 gaatttctaa gccattttgc atcataaatt cttcatcatt agttgcttca aaatacgttc
    16381 taataccata agctatatct gcatttatat gaaactgtgc tgttcctgct ggataatatg
    16441 cactgcattc attaccattt atagttctcc atgaatataa gcaaccttta tttattccaa
    16501 gttctctagc tctttctctt gatgcatcta agattgagta tctataatct aataaagctc
    16561 tagcaatgga tggttgagta tatataaaaa atggtaatat atacatttct gtatcccaga
    16621 aataatgccc ctcatagcca tcacctgtaa gaccttttgc tgatatatta gtctttccat
    16681 ctcttcctgc tgattgataa atatgaaata aattggtttt tatccccagt tgaagagttt
    16741 tatcgccttc aatctctaca tcagaggttg tccaaaactc attcattttc tttctctgaa
    16801 tatttttgac tttatcaaat ccaatattac atgcttctct taaaaccaat tctaatgatt
    16861 ttaaatgtgc ttctgattct aaacatttta acgactccag acattctaat gattttaaac
    16921 gttcttcatt tagatttaaa tcagaatata ctctactata gcctacaaca atttctaaat
    16981 ttaacctttc atcttttttg gcatagactt ctatttctcg ctcaatacat tcatctgaaa
    17041 cattataggt ctcatttgta atatttccac aagtaatata tgaatcaaac ccacaccata
    17101 accctaatct acttctttct gtaactaaat tcataaaata cttattgtta tattttttta
    17161 cattaatttt aaattgcttc ttatttatag atgccactct tgggtcatct actttttcac
    17221 aattaaactt ctccatacta ttttccattt tatttttaaa ttttattttt ccattaaaat
    17281 tcaatggtgt tattgtatat gaaatcatca ttaattcttc tatatcttgt gatactaatc
    17341 tttctataga tactttaact tttctaccac aagagttttc ccatataaat gaacgtttaa
    17401 gaatcccttc atttaaatct agtatcctag aatgttcact tgtaatacct tttgataaat
    17461 caaaataatc tccttcaata gagaaattta ctatatgagc attaggtaac ttacagatag
    17521 tctgattttg ttttgcatag ccataagcgc tttctccata tgtaattgga gattcttcat
    17581 aaaatccatt tacatatgta cccatattat ctacatactc attattaaaa tcagactctt
    17641 caatattccc tctaactcct aaatgtccat tcgctagtgt aaacagcgtt tcattggatt
    17701 ttattgtatc cttactaaac ccttgctcta taagttggtc cttagtagta aatattaaac
    17761 tcataataac actcctttct taaaatgaat tatgcatgag tttccatatc attaaataaa
    17821 atttctccat ctgtttctat tactttttta taccaaaaag cactttgttt tttagttctt
    17881 ttaaatgagc ctcttccata gtcatcagaa tcaacatgaa ttatgccata tcgttttgtc
    17941 atctttcctt cacttacact ggttacatct atacatcccc acataagata tcctataagc
    18001 tctattccat cttcatttac tccaagaatc atatttttaa tatgttcttt catgtaatct
    18061 atacgataat catcaattat ttttccatct tcatttacaa tatcttgagt acccagtcca
    18121 ttttctacta taaataaagg taactgatac ctttcatata actgattcat agttattctt
    18181 aaccctacag ggtcgttttg ccatacacta tttgattttg gaagatatgg attttttatg
    18241 gtttctggtc cgtttgcctt tgatttttct aaaccttcag ctctagctga actacaagca
    18301 ctagaataat agctaaaaga tacaaaatct acagtattat ccttaagtgt tgataaatct
    18361 tcctctttta ttattaattt tatttgattt gattttaaat aataattcat aaagcttgga
    18421 tacacacccc taacttgaac atcagaaaaa aacaaattat gcctttcatg ctctaaagtt
    18481 gcaaatacat cttctggttt acatgtgtat ggatatgttt ttccagcagc taacatacac
    18541 ccaaacttaa attctttatt tatatacctt cctatttcta tagtttttgc attagctaat
    18601 aattgatggt gtgctgcttg atattttttc tgaagttgat tttcatcagc tataaaagtt
    18661 aacccagcac ctatatatgg aatatgtatt atcatattca tttcgttaaa aggaatccag
    18721 tatttgacat catctttata tcttttcatc aaaatttcag catattttac atataaatta
    18781 accactcttc tatcagccca cccagaatat ttttcaacta gagaataagg tatatcaaag
    18841 tggcttatcg ttattaatgg ctctatatta tattttttta attcttttat tatattatca
    18901 taaagttgta atcccttttc atttggttca ctttcttctc ctgttgggaa tattcttgac
    18961 caagatatag aaaatctaaa acatttaaaa cctatttctg ctaacattgc tatatcttct
    19021 ttgtaatttt cacaaaattt aatccctata tgacttggat agtattgatt attttcattt
    19081 aaaatattat cctcatctaa acatacatct tttaatctct tatcatttaa tgggagttta
    19141 tcaaactgag ataaaccttt tcctccatct aaataaaacc cttcactttg attggctgaa
    19201 attgcccctc cccataaaaa atctttccct aatttcatgc atctacctct ttcacaatat
    19261 aaagttttat aatttctatc tcatatttag ttataagatt tttttcatac tatacctttt
    19321 aaataattca atttaaaaat ccaattatat tttttactca ctataattaa tattgtctat
    19381 tttcaatact ttcatattaa atatcaatat tagatatcta tgtatataat tatatatata
    19441 gcaaatacat ttttatatcc tcattattgt tatcttattc tcatatattg ctgtatattt
    19501 atatatataa aaggatttat ttcgaaatag aggttgtatt gagaactaaa atttagactt
    19561 tataaatgaa tggaattttc attgttgaaa tactgaaaat atatttgatt tcatataaaa
    19621 gaaagtgcct catgaactaa gttcattttg agacactccc ttttttttcc aagctattat
    19681 atcttttttt aaattctaat ggagagactc caattttttc tttaaatact ctgtaaaaag
    19741 tttttgtact tccaaaacca acttcttcaa ccaaatctac aatggatata ttgttattaa
    19801 gtaatatcca ctttgctttt tctaatctat attcatttaa aaaagttata aatgtttttc
    19861 ctgtattttt tttgaaaaat ttagtaaaat aatatacact aaatcctact tcataagaca
    19921 catcttctaa ttttataggt tgtttataat ttttttctac atatttgaat atattgttca
    19981 atctctctaa tatctcttta gagtttattt catattctac tgtattttct tcaatttctc
    20041 taggaatctg tctatataat ataggaatta aattatacat tttacctttt attgcataac
    20101 tatatccttc tattttgtat aggtcttcat tgtagatatc tatcaatata tcgaaaactg
    20161 actttcttat ttttgctgac caatctctac tacatttttt tatactactg aataaattaa
    20221 ttaagctttc tttctcctca tttaataaaa ttaaatcatt aaaaaaagat atatcaaatt
    20281 gaaatactaa tctttcactt cccggtgatg gcagtatata atgaatatct cctcctttta
    20341 ttatcactat ctcgcctttt tttaattgca taggcttgtc atttataaat agatttacta
    20401 caccttctgt tataagtaat atttctattt ccttatgcca gtgtggtgtt gttaatactt
    20461 ctccttcatt tgatagagta cgaaaaggaa attcatgtat taatttaggc atttctaaat
    20521 atattgccat atatatcctc tcctctctag tgtctaaaaa ttaatttata ctatttaaaa
    20581 gaatacacat tttattttaa aaacctcaaa tttataattt atacaatacc tacacttcat
    20641 aaaatatatc taatatttct ttttttgtat gtgcatttaa aagtctttca cctatatttt
    20701 taccacctaa aatgtaagct attttagata ttaatatcat atcttcattg cctccagatt
    20761 gtggcatagc aaacataatt attactttta caggtaagcc atctatactt ggccaatcta
    20821 cacctttttt agatttacct attactacag atgccttctt tacatatttt gtttttccat
    20881 gtggcatggc catttgataa cctatactag tagagcctat tttttctcta tgttttaatg
    20941 cctttataaa cttacttttt aaagttatac ttcctgtatc gtataattta tctactaatt
    21001 cctgtattat gccttctttt gtagttgatt tcaaatctaa aataatgctt tcttctgtta
    21061 atatttctct aatttccatt tgttttctcc aatagattat tcttaaataa tattttaata
    21121 tcctctttgc tcttgcaatc tattatatag tttatatagt tcttttgcct atataaattt
    21181 gatatttcca ttaaaatatt ctttaaaaaa ctttgattac taatttctaa ataaatatca
    21241 atagttctag taacattatt gatattcatt atccctttat ttaatttact ttgcttatgt
    21301 atatatatat ttaaatcttt tcctaatgaa atagattcat atttactccc taaattcaca
    21361 cctattaaac tttccatctg agctacatca aaattaaaat atatattatc ttctaaatac
    21421 attcctaata agtttgtatc taagttcata ctttttttag gtttagaaag taaagcattt
    21481 tttatattat taatatcatt ttccattaat agtactgata caactatatg taatttatct
    21541 ttcaaatcta agtttacagt agatattaca aagtctacat catctaaatt tcgcttactc
    21601 aactgatgca taggaactat atcaactata gtccattcag gaaattctct ttttaatctg
    21661 gctgcaagga gctgagatgt tccatatcct gtatgacaaa ctactattac tcttttacta
    21721 ctcatatttc tttctattgc cgcttgaaaa tatgtggcaa gatatgaaac ttcatctata
    21781 ctaatattct tcagattatc atactctgtc ataatattta tagtcatcat acataatccc
    21841 agcacatctg aaaatcgctc ttgtatctct cctaacaacg ggttttttat ttggatatca
    21901 tatcttaatc tgtttaacat aggccttaca tgagatgcta gacttttttg tagtaagtca
    21961 tcatttttga gatttatatt taaaaattgt gacatattct ctatcattat agatgaaact
    22021 ttttcacttt cacttaatct atctgattca tcattgtaac tactattatt ttcgctacta
    22081 aatccagatg ataccaaaaa aatatatatg tacataagtt catctttcgt tatttttact
    22141 ctgtatctat tttctatttt atctataagt gtagtgacat ttttatatac taactcgtcc
    22201 aaattatcta cagaaatttc tctttctttc tgagattcta tttgattacc ttcttcgatt
    22261 ctctttaaac atataagtat atgggtaatt aaatttatat agtagggctg atttatagta
    22321 tatcctaaat tgtattctaa ttctgtaatt atagtttcta caaatataat agaatcaata
    22381 tcaaataaat ttatcaatgc actaaatgta gcagaatcta atcttgttaa ctcagatata
    22441 tcatgttgtt cataattttc atctaataaa tcatccatca ttttggcaat cgatttcctt
    22501 atatccactt ctttacctat aatcttagtt ccttctaaag ttttattaag ttttaaattg
    22561 tattctttta tccatgcctc tatatattta aaatcattta ctatagaagt tttacttaca
    22621 taatatttat ctgctaactg atttattgaa gttatattat ttgaatttag caataaatac
    22681 tttaaaatct ccattcttct ctgctctact gataaagatt tattttcctt cgattgtata
    22741 tttaaactat taattaagtc tatgttcttc tttgctaaat cttctattaa tattccatag
    22801 cctcttttta tatcaatttt tatattaaaa gtttctaaat atttctcaat catcttcaaa
    22861 tctttttgta aagttttatc agatacattt aatttatctt taaagtattt tataggtcta
    22921 tatttatttt cgtttagtat caatttaaga aattcaattt gcctcgacac aagcatactt
    22981 agccctccct acctatgttt atatatttct atgtttatat taagtactat tttaacatat
    23041 ttactaacta tgtaaaatta ctaagatact tctgtatcat aaaagaattt atgatacacc
    23101 ttactaaatt gatataataa gataatataa tttcaaaata aaaattaagg atatttagaa
    23161 gtagttaact gattctaaat atccttatta ttattctata tacttgttgt tattccatta
    23221 attattttta ctattattta taatttaagc accaagtaat tcaacttcac tattttcact
    23281 ccttatagta ggctttgtta cccctataat caatgctgtt attactgtac caatcaatat
    23341 acaagctata tatgcaactg gtgcactaca tgcaaatggt attacaaata ttcccccatg
    23401 tggtgccatt aaagttatat ctaaactcat acatattgcc ccacctatac aagaaccaat
    23461 tatatttgct ggaatcattc ttaatgggtc tgcagctgca aacggtattg cgccttctgt
    23521 tatgaaagat gcccccatta tagcagttgg tagagatgac tttctttctt ctttagtaaa
    23581 cttatttttg aatattaaca tagctaatga tattgctaat ggaggtacca ttcctcctac
    23641 cattaatgct gctgatggtt caaatatatt acttgaaaac atagccaatc caaaagctga
    23701 agctgtttta ttaataggtc ctcccatatc tgatgccatc atccctgcta atattgcacc
    23761 taataatact ttattagttc cagacatact ttgtaaccaa gattgtaaag cttcatttaa
    23821 ccatgatgct ggcgtattaa ctacaaagaa cattatagct ccactcgtaa atgcaatcaa
    23881 aagtggacat atcaatacag catttactcc ttttaataca tctggtaaat tttctgttat
    23941 cttcattact cctaaagcta tatatcctgt tgcaaaacca gctaccatac cacctataaa
    24001 acctgaacct ccaataactg ccataaaacc agctatcata gcaggagcaa atccttgtct
    24061 tcctgctatt gatttagcta taaaaccagc aagtatcggt ataaataact taaatgctga
    24121 atcgcctcca agttgtccaa agaatccagc tatagggttg tatgtttcat gagttgggtc
    24181 tgatgcaaat ataccaaaca taaaagctat ggctatacca attccaccta tcactacaaa
    24241 tggaatcatt tcagatacac cactcattaa gtgcttataa acaccctttt tctctgaccc
    24301 ttgaagcatt tcttttgaat cttctaaagt ctttccacct ggtttaattt ctttagccat
    24361 tccattttca gcgtttataa ttaaattttt agctaatgaa acattcttag catctactac
    24421 tttcttttgt agcactttct ttcctataaa tctactcagt tgaacttctt tatcacaagc
    24481 tattattacg tattcagctc tttttatatc ttctttagtc aacttatttt ctacacctat
    24541 agctccatga gtttctattt taacttcata tccaagttct tgacctgctt cctctaatgc
    24601 tttttttgcc ataaaagtat gagctatacc tgttggacat cctgttatcc caactataag
    24661 acctttattt tgattattac taaaatctcc tgattctgca gctttattat taaatatact
    24721 taatatttcg tatggagttt ctgcacttag tagatgctta agaaaatttt cttccattag
    24781 atatgtagct agtttagata taatcttaag atgttcatct gaacctgatt ctggaactgc
    24841 tatcataaaa aatgacctaa gtttttgacc atcattatct gtaatctctc tatctgttct
    24901 taaatacatc attacaggtt gatttactac atttgactta gcatgaggta tagctattaa
    24961 attacccata ttagttgatg attctttttc acgtttatta atatcagcta taaacttttc
    25021 tttattattt atataatttc catggtacaa atgatttgcc atataattaa ttacatcttt
    25081 ttttgtttgt aattgtttat ctagtacaat acaatcgctt cgtagtattt tacctatcat
    25141 aaattctccc ctccttttaa tttgttacct cataattaat ttttattttt ataaaagcac
    25201 tttaacttat ctatagcatt gaatagattc attttaaact ctataacttc tcttgcagct
    25261 tttatacatg gtggatatat agtatctggc tcatataagc ttgggttttg ttctaatagt
    25321 tctctgcact tcttataata tgccgactta acatcactcg aaatatttat tttacaaact
    25381 cctagtttaa ctgcttgtgc tatttcttca tctggatttg atgaaccacc atgaagaact
    25441 aaaggtatat ctactacttc tcttatttct tttaataaat ctagtttaag ctctggttta
    25501 aaaccttttg gatatatacc atgtgctgta ccaattgcaa tagctagtgt ttctactcct
    25561 gttttttcaa caaaatcctt agctaatttt gaatctgtat atattatttc atcagtacca
    25621 ccttcacttg atgttcctgt tgttcctatt gttccaagtt ctccttctac ggacacattt
    25681 aatccttttg ctatttctac tatttcccta gatatagcta cattctcttc atatggtaaa
    25741 tgtgagccat caatcattac tgatgtaaat ccacatctta ttgcctttaa tatttgttct
    25801 ttattttccc catgatctaa gtgtattacc ataggtactt tactcttatt tgcttcttct
    25861 atgcaactag ctacaaagct atctcctaga aaacttagct catttgggtg tattgcaagt
    25921 attactggtg catttttttc gttagcactc tgtactactg ctttaagtat ttgcccactt
    25981 cctatattaa atgctggtac agcaaattga ttttcttgtg ccacttttag catttccttc
    26041 atatttatta acatattgta cctcccgata ttttaaattt taggttgaat ttgcttcttg
    26101 ttaattttgt tgttgtttat atttaaataa tatcagggta atgaagctca gaaaataaca
    26161 atcgttttcc ttagtgaaaa ggaactttta ttatacactc taagttcctt ttcactaaat
    26221 aatttttaga agtctgcatc atagttaatt atatttctca tgtacatctt ctctttttaa
    26281 gtgttttatg ctttagcctt cctagatttt ataataaaca attaagatac attaactata
    26341 aatttaaaga tactcatgca atagttaatg ctatattaga gtcaaaaaaa ttaaaaagat
    26401 attagctatt tggccaatac cttttcttgg attccaatag tatatacgat ttatagaaat
    26461 cttactcacg attatctaat gttttacttc cataaacttt gcataaaaca ccaaagtgac
    26521 accctccaaa ttcatctcta gctaataaag tgatttggtt ttctaagcac caatttataa
    26581 attagccttt gttatcttat gtaaatcttt ttctatctaa tttaaaaatt attcctaatg
    26641 ctatatagca tataccaatt actaatacac cataagccat agatactcct atcttaaatt
    26701 cttgcatatt aattacaata gaaactgaaa taggtttatt acaaacacca taaagcaagg
    26761 ctgacattgt atattatcca attgtatgaa tgaatactaa tatagctcct tttaattaaa
    26821 tgatgctata taaatcatat ttatcccaat ttttagccta acttctttat attccttttt
    26881 aataaaaaaa gatattgact aaatagtcaa tatcttttag ttgatttaaa tacccacaat
    26941 tttaatctaa tttttaagtg tttccttaac ataatcttat aaatattaaa atttatctac
    27001 ctataaaatt tctccattaa attttattac attttatctt aaaacaatta taatctgacc
    27061 ttaatcatat attatataaa tatttttaat aaattttata tctaattttt gattatccgc
    27121 ataaacacta tacattcaag cattttgagg tatagaaaaa aactcatttt accacgaatt
    27181 taccacgatt gaatgagcct tgatatgaca gtaaaaccac tatgggagat agcacaaata
    27241 actgtgtatc tcccaatttt cttttataca gttgattact tcactcgtat ttcaaatttc
    27301 aagattgctt tcatcatatc tgtataaact tctcctttta gttcttcatc aacctgcata
    27361 atgattttac cactttcaca gtggtaaaac ggtcgcaagc ataatttaga aatataagcg
    27421 tcataaaact tcaaaatttc tctgattgcc acctcatctc cgcttgacgc tctgcaaatc
    27481 aattcaaaag agggatagcc ataatctttg ctcattcttt ttacttcctt tcgcttaaaa
    27541 gcatttttaa cttctttagt cctctacttc ttctgctaaa aatagcagaa cgtgatacat
    27601 ggtacaattc tgaaatttct ctgtcattca tgccttgaaa ataacgtaat aaaatcgtac
    27661 tacgctgttt tttcgatagc atatttaaag ctgtagcgag tttttcatct gttacacaaa
    27721 tcgtaaaatg aaaaacttga aacgatacat aatcataaat gtatgtatca actgttccct
    27781 gttcaagccg ttctgtttct gacatttcgc aaaacagaac ttcattttta gagcgtttca
    27841 taatctgctt tttatgatat tttaccctgc ccttaatgat aatcatcatc aaagaattaa
    27901 actgcaatct gacaatatcc ttgaaagaag atgtattcat aagttcaccc cccctttctg
    27961 caaaaactga aatatacaaa cggaatattt caatacggaa aatagaaata ccgtctatac
    28021 ctttggtttc gtatcagaaa agaaagtgtc tatgaaaaaa agcccgcaca aaacatattg
    28081 ttttgcacga gcctttatat tgaaaaataa aagtaagatg ttttaattac tattagtatc
    28141 tatcttcttt aacgcttcta aagttatatc taaattgtct ttatgccaat tttctaaagt
    28201 gattccagct ttttttgatg tcaaactgcc agaagttcgt aaattgctta gctctttttg
    28261 ctgtgttgat agtcgaataa tatctgtatc tgttgtaatt gaaatgatat aattcaataa
    28321 atcttctgaa atctcaatac ttttaattcg agaatatgga attactaaaa gttcttcttt
    28381 ttttaacgtc atattcaatg tcataagatt gaatggtatt aacacaattt catgctcaca
    28441 aagttgtagt acataaaatt ccgaattgaa aaattcgaga atctttgcac tcaaattatg
    28501 cggagcgtat tttacaataa tacatttgtt ttcaagtgct ttcaatccag cctcatttat
    28561 aaccttatag accttttttt ctgttgccat aatacattcc tccttgagtt tttatattcg
    28621 cccttatttt atactatttc attctaaaag taaagtattt cttacattta gaagcaaaaa
    28681 aattcttgct ctcatttatt taaaatagtt tatggattag tgaatcatta ttataggttc
    28741 agtcctttca attttgttca ttaaaatatg ctctaaggcc ttttagataa gcgaaattat
    28801 aaatatttca attgacgttg cctttttaaa ttgagaacaa atgtttccca tttcttttct
    28861 tgcttttcat atcaaggata acacgattgt attccttttg catatccacc ttattttaag
    28921 tgatttttgg tattcgtgtt catctcttca ttggatacac tactgtcttc cacctgatta
    28981 tcaataattc actgcatccg caattctcgc atgacaaatt tttccaacta ctgtttagag
    29041 taatcttctg atacatcaat ttcaaactct tcaaataatt attgcatata atttccatgt
    29101 tggacggtag ttgaatttca ttattgtcag tcaacgtcca aaaatccgta atgactacat
    29161 gatctctact gatactttga ctgaaattat ttttttgttt aacactaatc atcaccattt
    29221 ttcacattca ataatttaat tgcagtttca atttttacaa acgacttttt agctccactt
    29281 gagtgatgcc tatttttctt tctaagattc cttttatcat aaatatccta ataagtttat
    29341 ttatcgttac taaataaatt attagggtac ttcccacgtt ctaaacatca ctctcacctc
    29401 aagttactgg ctattggttt tttgatagtt tccatacaat tgaccgcaag cagcgtctat
    29461 atcaatgcca aattgacttc taatggtaac tttaattcct gctgacttta attctttata
    29521 aaagttgaca agacatttct catttgcttc ttcaaaccgc atccgtgaac taacagtcgg
    29581 gttatatcta atgatgttca catgatacaa gttcccactc ctatatctac ctcttaaaag
    29641 gtttacgact tctttcgcat gttcaataga atcattaact ccgtgcaaca taatataagc
    29701 aatataaact tttcttgagg ttactcgtat atgctcatct aatgtatcca tcacatctga
    29761 taatgggtag cgttcattaa ttggcattaa ctcacttcgc tgttcattaa aaggagaatg
    29821 taatgaaaat gtcaggttga cctgcggata gttttgagtc aattttttaa tgtttggaat
    29881 aattcctata gtggatatag ataacctacg cggacttaaa gcaaacaacg caggatctgt
    29941 aagtacattt aaagcatcaa aaacttgtac attcgctaat gcttctccca ttcccataaa
    30001 agaaatactg tcaattgaat gcccttgtaa gtgaaagtac aaaatctggt cagtaatttc
    30061 atctgaagtt aagttacgtt ttaaacctat atctccagtt gcacaaaatt tacaaccaaa
    30121 attacaaccg cactgcgatg atatacaaaa tgactcccaa ccagctttat atttcatatt
    30181 taccgtttct attttttcgt ctcctgaaat tccaaataag acttttgaaa cttgtgtaga
    30241 ttgttgtgct tttaaaggaa caatatttaa aatcgattct ccaaactcct caattaacat
    30301 atctcttagt gatttaggaa gaaccgttat ttcgttgaaa ttatttattc tccctgggaa
    30361 tatagcattt gtaatttgtt tcattctata attaggaaat ttattctgct tcaagaactc
    30421 ttgaattctt atatacttat ttttttgttg catgttttct catccttcca tataactctg
    30481 gtttgtttgg acctatgtca atactttgga cacaaaaagt tgaacatttt ctctctgcat
    30541 gatattaata cgtagagaaa gattaccaac ttttgcattt ttaccaaaca aaattctaaa
    30601 aacagttaac attgctttca cctctttctt gtcaatataa gtgttaaata gtataccata
    30661 aatctttccc tatgtaaact caaaaaaata catgtaattt gaaaaacaaa caattttgga
    30721 tataaatgta gttaaactaa cctgcaccgt ttaccgttaa catttagatg aaaaacaaga
    30781 aatcttttat ttattcaatt ttatttaaaa ttaaaattgc aataatctca ataaatatca
    30841 tcgtatcata aagccattgg attacattgg cacaaaaaac ataacctact tccaaagtat
    30901 caggcaccat tgctccaact gcttttgcaa gtaaatttgc cataattata aaatagataa
    30961 aggcaatcgc actagctttt cctttaattt tccacccacg ttcatctcga ttttgttttc
    31021 gtacaaacat tacaatcaat atcaatgtaa gtgacaaact tgcccatgca ccaattatca
    31081 aaacagtttt actgttaaat acattccata aaaattcgta taatgataac acagtcaatc
    31141 ctccctaaaa tcaaataaat cttcaatcgt tacatcaaac actttcgcaa tactgtatgc
    31201 caacaacata gagggattat aacgatttct ctcaagctgt ataatcgttt gtcgtgatac
    31261 gcctacaagg tcagcgagtt cctgctggct cattcgtttt gtcgctcggt aaacatgaat
    31321 tttgctatca aacgaatatt tatttttctt tgccactcat acaccgcctt tatcgtaatt
    31381 ttccatttcc gattataaca tatttcttac attttgtgtg gctgttttta ataccttatg
    31441 agaaaatcgt gcaactatcc ctttttccct cttgattacc caacacagaa cagaaaaagc
    31501 cctgtcaaga gctttgccac cattggtggt gctttgcact cttgatcggg ctttttgttt
    31561 gctgtatctt ctcacaagag gaaaaagatt actcgtcctc atcatcaaaa tggttattcc
    31621 ctaatacttc ccgtaacagt tccatatctt cttttgagtt ggggtttatc cgtttcacga
    31681 attgaaaagg tgttttatac ttatgtccct ctatgctttc cccaaacata tccatgctgt
    31741 ataaatcatc atatcggtct aacaatcttt gaaacttcaa atgctggata aattctttaa
    31801 ttgggtaaag gtcgcctgcc tgtatgttat ttccgttgat gtagtcggta atatattccc
    31861 gtaacttttc taactcatat tccagccatt cttcctcact atcaaaaaag ttgtcataat
    31921 gcccgtgttt cagttctgta tttaggcgtt cttcggctct tagaaactga cagacttcct
    31981 tttcagcctg attgatatat ttccattccc ccgacaacag ttcattgggc gttacgtcca
    32041 gcacttccat tatcttttcc agcgtatcat aggcaggata attcaatcct cgttcaatct
    32101 tggaaaggct ctgcatattg ataccgattt tgtccgcaag ctcctgctgt ttcattcctc
    32161 tgtattttct gatggtctgt atgttgtttc ccaaaaaatt tattttcact gcataaccct
    32221 ccgtaactct gtatatcttc ttatttcgtt tccgttataa gtctatcatg cttaatatgg
    32281 tttgtaaaga caaaaaaaga tattgacaaa taagcataca agaattatta tgtgtttgta
    32341 aataattaag cacaacagaa tgaaatataa aaccatttaa aaagtaaatc ctatctgatt
    32401 aaacccgtag atatgaatat cggttgatat ggcatggtta gaaaaggaca aacagggttt
    32461 gcagacaaag cattgcagga ctgctggcgt gcgtcagcga caacgccatg acggctctgc
    32521 cgtcaaagga cggaaatgct ttgtctgctg gcgagcctgc gagccttacc tgtgcccccg
    32581 ttatctaaca ggggggcact attacaagcg aaactatcca aaaaccatac aatcccaaag
    32641 ctgtgaggaa taataagaag ttttaagaag atagtgtata tcatactttt tgaaaatagg
    32701 tttacaggta tttcaaggct gttgtgggat tggaggaata caatgaacaa cttagaattt
    32761 gcacttgaaa tgaagaacaa acgccttgca agcggtcttt cgcaaggaga acttgcaagc
    32821 cttacccatt tatcaagata cagtatcaac cgctttgaga acggaaaagc caacgctagc
    32881 agggaaacac aaaatattat cctgcgttgt ctgaattact atgtctgtga taaacctttt
    32941 tatctgctag tcgattacct gtctgtacgc tttccgacaa cggacgcatt agcaatcatt
    33001 agaaaggtgc taggcatgaa agccgattat tttatccatt atgattacgg gtattatggc
    33061 tataaggagc attacaccta tggagaaatc aaagtcatgg tatctgatga tgaacacatg
    33121 ggcgtgttct tggaattaaa aggggcaggc tcacgcaaca tggaatacgt cttacaggca
    33181 cagaacaggg attggtattc attcttaaac cgctgtcttg actgtggtgg tcttatccgt
    33241 cgctttgatt tggcggtcaa tgatatgtgc ggtctgctgg atattcccac cttgtctgaa
    33301 aaatacaaaa atggcggtgc ggattgtcgc tgtaaaaact atgaaaatgt gcaaggtgga
    33361 aaattaagcg gaaaaaaccg tgatttagca agcacccttt atatcggctc aaaagcaagt
    33421 acaaaatatt tttgcctgta tgaaaaacaa aaggaacagg caacaaaaaa gaaacatacc
    33481 gatattatca accgttttga aattcgtctg cgtgatacaa aggcagtaca ggcagttgaa
    33541 gaactgttac tgacctataa ccctcacggt ctggtgtttt atctcattac ggactttgtg
    33601 gactttcccg actatccatt atgggagata ttcacttccc atgacagctt accgtttgaa
    33661 atgaaccccg tacccgtcaa tatggaacgc actctgcaat ggctggaaag acaggtcatg
    33721 ccgtcaatcg tgatgataga ggaaatcgac aggctgacag gttcaaacta catgaaaatg
    33781 attgatgaat gcaaccacct ttctgaaaaa caggaaatga ttgtggaaca gatgtgtacg
    33841 gatatagcag acgtaatcga aagtgagggg gtgttttatg agtaatgcac aggatattcc
    33901 cgtatgggaa aaatataccc ttaccattga agaagcgtca aagtatttcc gtatcggaga
    33961 aaacaagtta agacgcttgg cagaggaaaa caaggacgct ggctggctca ttatgaatgg
    34021 caaccgcata cagattaaac gccgacaatt tgaacaggtc attgataaat tggacgctat
    34081 ctagtgcaaa tgagccttgt atgtgttaag atgaaaacaa gtcatatcaa ggctctttcc
    34141 aacaaggaaa ggagcatgac accatgaaag aaaaaagacg ggataacaaa ggacgtatcc
    34201 tgcataccgg agagagccaa cgaacagacg gaaaatactt atataaatat gtggacgcat
    34261 ttggaaacac aaaatatgtg tatgcttgga gattgacgcc aacggacgta acgccaaagg
    34321 gcaagcgcca tgatatatcg ttacgggaaa aagaggaaca gataaaaaaa gacctgttag
    34381 acggtatcga cagcacaggc aaaaaaatga cgctttgcca actctatgcc aaacagaacg
    34441 cacagagggc aaacgtaaag aaaagcacac agaaacagag agaacagctc atgcggttat
    34501 taaaagagga caagctgggt gctaggagca ttgataccat aaaaccctct gacgctaaag
    34561 aatgggcgtt acgcatgaaa gagaaaggct tttcctataa caccattaac aaccataaac
    34621 gctcgttaaa agcgtcattc tacattgcca tacaagatga ttatgtaagg aaaaatccct
    34681 ttgatttcaa gctgaatgaa gtcatagaag atgataccaa agggaaagtc gcattgacag
    34741 agggacagga acaagcccta ctctcattca tcaagataga taacgtgtac cacaagtatt
    34801 atgatgatgt gctgatactg ttaaaaacag gacttcgtat ctcggaacta tgcggattga
    34861 cggtcaagga tattgatttc aaaaatgaga tagtccatat cgaccaccag ctattaaaga
    34921 gcaaggaaca gggctattat atcgaaacgc ctaagaccaa aagcggaata aggcgagtgc
    34981 cattgagcga ggaaacaatc aaggcatttc aaagggttat caagagccga ccaaagacaa
    35041 agccgacaca ggtagacgga cacagcgatt ttgtatttat caatcacaaa ggcaagccga
    35101 aagtagcgat tgattacagc actttatttg tccgtatggt aaagaaatac aacaagcacc
    35161 ataaagataa cccactgcca cacatcacac cgcatatatt aaggcatacg ttctgtacaa
    35221 aaatggcaca caggaacata aacccgaaag atttacagta tatcatgggt cattccaata
    35281 tcagtatcac aatggattgg tatgcacatt cctctattga gagtgccaaa acagagataa
    35341 agcgtctgat agcatagaag tatttaccac gaaatttacc acgtttgaga gagaaaacat
    35401 aagaagatat gccccgatat gcgaacgtga acagaaagta taaatgcccg tagagcctat
    35461 aaaataaggc tttgaggaca ttttataaga tatgaaaaga taggaaaaaa gtgatatata
    35521 atttatcatt aaacttaata attaaataac tatatttcat tatccatctt ataaatgttt
    35581 ataaactttc cactattctt cttcaataaa ttcaaacaaa ttttctactg tagtatcgaa
    35641 tactttagcg atatccatag ctaacttcaa agaaggatta tatttcccat tttctaagtg
    35701 tacaatagtc tcacgtctta ccccaaccaa tttagcaagt tcattttgcg tcataaggag
    35761 tttttctctg tattctttaa tttttgtttt catcaatatt gccacttagt tacatatccc
    35821 ccttttatca aagtatatat acaacactaa tttagataaa gactgtataa ataaaactgc
    35881 aatgaggatt atacctgtat ctaggtttga tatatttata ttacttgtat aaggtgttgc
    35941 aaagaaaata gatattatta ctatagaata tatcattatt tttattgcaa tcttattaac
    36001 ctttgatagt ataaattcag atgattcatc aactaaatca ttatattttt tattataaat
    36061 tgaataacat ccaaaaacta ttaaccaact caaccctgga agagaagcag tgcttggacc
    36121 tttaaaaata tacttagtgg ctaatacagc tataaaaaaa taagttatta caatcaactc
    36181 caggataagc tttgatctta caccagtttc tgatttagac atataaaatc actccttaaa
    36241 aattatattc tctatactct ttaattttcg tttttatcaa tattatcact tagttgcata
    36301 ttccctttct atcaaaatgt atatacaaaa ttaatttaga taaagattgt ataaataaaa
    36361 tagctaagag aattacacct atatccaaat ttgatatatc caaacctctt gtataatttg
    36421 ctgaaaagaa aacagatatt agcaaaatag aatataacat tatttttgat gcaatatgat
    36481 caacctttaa taacataagt tttgacgcct cgtcaactaa atcattatat tttttattat
    36541 acatgaagtc acatgcccaa aaagcgaata aaattataaa agtaatacaa agatttccct
    36601 ctttaaaaat aaactttttt aataatgagt ctataaaaaa ataggatatc ataagtaact
    36661 ctgaaacaag atttgtttta acaccaagct ctgatttaga catataaaat caccccttaa
    36721 aagttatata tttataacac cttatgttat aaatatataa cttttccaaa taaattgcaa
    36781 tagaatattg aaaatattca ataatatctt cataaatata ttttataaaa gattttataa
    36841 taaacattac aatacagtac taaattagtt tatttcatct atcatctcaa tcatatcatt
    36901 tactaactat tattctaatg agcatataac attgaaactt ataattatac aacctaaatg
    36961 cctcccaatg taccctcaaa aacatcattt cctgtaactg aagtataatt ggtatatttt
    37021 atcactgaaa taaaaaagca ctagtcaata aagactagta ttttcaagta ttttatcatt
    37081 ctttttttaa ttattggaga cgaatcatca gaataatgcc cataatttat ctatatgcaa
    37141 attctaaatt taaaataaag tttcagataa atttactatt ctatgctatg atacaacaga
    37201 aaaaactgaa atctatgagt ggtagcttca tataatccta gttcctacag taatcaaaac
    37261 tgaggtttat tctatatgta actaatgata aattttatta taggagttat tagctctatt
    37321 tgtgttacta taagtagtaa ttatatatat gataattttt taacactttt ctgttggcta
    37381 tatagaaagt ggtttagaat ttaaatttaa ataaaattta aattcaccaa aaagaaatct
    37441 atattagaaa ccactactct attccaccag attgtaattt tttgttcttt atatcacagt
    37501 gctataccat attaaattga aaaataagtt ttaaatttat ttgttacaat tcattaattc
    37561 aaaaaaatat tttgagtcat gagttttgta aagatttagc catgaattta atgcttctga
    37621 ttcaaaaaca tctaaaagtt tcaatacttg aaacgtaaat tccaacggag caattcctga
    37681 agccgtaact aaattttcat cactaactac agattccgtt ttataatatt tttctccaga
    37741 gtaatttggt attaccattt taagaaactc taagtcatta cttgtatgat ttctaaaatc
    37801 taatagccct tttttagcta ggcctaatgt agctccacat atggctgcaa ctatagaatc
    37861 ttgtattaaa gcttctttaa ctttttctaa tattatctca tgattcatgg ataaccaagt
    37921 atttccccct ggcaaaatta ataaatcctt actttccata ttaaactcat caactgtaat
    37981 ttcaggtaaa actcttaacc cacccattgt tataatagga tttttatcaa ttcctacagt
    38041 aattactttt agtggtttta atcctttttt aaaatatctt cctgtattta attcagcagt
    38101 taaatatgcc acttcccaat ctgacatagt atcaaataca tacatatata cttttctatt
    38161 tttcatcttt tttactcctt atgtaattaa tttatatatc taattataaa ataacttaac
    38221 tgacatattc agtcagttaa gctattaaat ttgataataa tcaattaatt ctagtaaatc
    38281 ttcaattatt ttcttcctaa ggcttagtgg ttcaattact tgtattgtct ttctataagg
    38341 taaaagtata tttggtatgt acttgcatat tacttcctct tcaagcataa atattatttt
    38401 attaggtgtt ctttctttca agtagtgccc taaaaaccaa tgttggctta aactatctaa
    38461 agaatctata ctcccttcta caactaattg aattatattt tgttcatctt ttatttcagg
    38521 tataattcct tttataaaaa attcacttgc tgaaaattct gtcggtctgt taaatgtatt
    38581 tgatgtttct atgatttcac taatcctatc cactctgaaa ctacgtacct catttctcat
    38641 attacaaaat gcaactacgt accaattatt attccagtga acaattccat atggatttat
    38701 aattctatat tttgattttg ctttacgacc tgcatgatag ttgatttcta cagatagctc
    38761 ctttaatata ctattctcca attttttaag tactgattct atagacactt tcccaattgg
    38821 ttttattact tcaagggctc ttaagtggtt tgttaaaata tcttcttgtt tttgatttga
    38881 atacattttt aactttaata tcgatttatc taatgcttcg tctaagaagt atccttcttt
    38941 tttagcaaat agtgctgcat gaagtagaga tttttgctct tctatatcaa aaaaaagagg
    39001 tgctttagta aaattattta aaaggctata cccaccatta tgacctgtat ctgaaattat
    39061 aggtactcca ctcgcagaaa gtacatcaat atatcggtac actgttctta tatttatttc
    39121 taatttttca gctatctgtt ttgctgtaat ttttttgtca gagtttaaca tccacagtat
    39181 agacatcata ttgtcaattt tagccatgta gtttcacctc tttctatttg ttatataaag
    39241 ttattatata actttttgat tgatttttta caaaaaaaca ttagtaaact gctaataatt
    39301 tatactaaga tttatttcaa atatttatag atagtctttt tctatagtta agttatccat
    39361 taaattacat agtagtatat ccattttagt tgatatattt tcagctacct cccttgaata
    39421 ttattacaat aagtctaaat cttctttctt ccataaatat attatgagga aagactatca
    39481 tctttaatgg tttaatagta taaaagatat taattttaaa aaatctattt ttatatcaga
    39541 tgggtattgt tttttataaa actgaaaaaa tcacctaata gaatctatga ttttttaaca
    39601 taacctccat aaattagtac caattatcac ttcaaattca aatttttatc tgaagaatat
    39661 acaatcatat ttccatactc aacataatat tgagtgtttg gcttgtattt acaaattatt
    39721 attctaacaa aaacaactat acatagatta aaatcatctt ctaaacataa ctactaaaat
    39781 tgaattaatg atatcaattc cattaatctc ttttaataaa aaattctctt ttctatatga
    39841 aaattatttc aaagctttta agttaaatac aaaaatgact ataaatagat ttttatttac
    39901 acaaatctat ttatagtcac tatagtttat ccaataaaat aataaaataa atatgtacac
    39961 aataaatgtt atttacgtct taagtattta tttgttagat ttttaattaa aaaaaacaag
    40021 ctaatgaaca ttaatgctaa atctagcatt atattgcttt gatctcctgt ttgtacattt
    40081 tgacctacat tactatctaa actttcatct gtatctatat ttatatccgg ttttccatct
    40141 ccatctatat ctatatttac atccggcttt ccatctccat ctatatctat atttacatcc
    40201 ggctttccat ctccatctgt atctatattt atatctggtt ttccatctcc atctgtatct
    40261 atatttatat ctggttttcc atctccatct gtatctatat ttatatctgg ttttccatcc
    40321 ccatctgtat ctatatctgg tttgctattt cctccattat ctatatctgg tttgctattt
    40381 cctccattat ctgggtctgg tttactattt ccaccgttat ctggatccgg tttgctattt
    40441 cctccattat ctggatctgg tttaccattg ccaccgttat ctggatctgg tttgctattt
    40501 cctccgttat ctggatccgg tttgctattt cctccactac ctgaatccgg tttgctattt
    40561 cctccattac ctgaatc
//
LOCUS       DAMJXI010000033        40223 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.035, whole genome shotgun sequence.
ACCESSION   DAMJXI010000033 DAMJXI010000000
VERSION     DAMJXI010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 40223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40223
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.035"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            297..674
                     /locus_tag="PC465_002166"
     CDS             297..674
                     /locus_tag="PC465_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2649460.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDVTVTSKDVIEAMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTIRVKHKDYLSFETKDFLSNIHDDSLRSLISALH
                     DDENIGKDKLDFLESYFDNLKDE"
     gene            667..1701
                     /locus_tag="PC465_002167"
     CDS             667..1701
                     /locus_tag="PC465_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="HDF2649461.1"
                     /translation="MNNYMLYVFENLIKTTIVCSLGICLLLFLKRYLFKKFSKRFNYY
                     IWLIIVFRMLLFLFNYTIVYEVKEPKENAVRNNITQIDISTDNNLMLYVAYLWLFVTI
                     VIAVYTFIKYTRFKNLVVDVSYDIEDNDINCIYKNLLKELNIKKKIELRGSDELVSPA
                     GMGLFKSYIFLPDYPYSKDELTWILKHELMHFKNKDILIKFLVLSVRIIYWFNPLVYV
                     MSNKVNLDCELCCDESVLIDCSLKNKKEYALALIKSIKLSKNYNSGILTTEFNKTSLE
                     KRLDSIVKKKGKSGILVLLILITLFSVTYFNFESISFDNSNSLRNMGILQKSGVDLKE
                     EDDISMRVIN"
     gene            1767..2354
                     /locus_tag="PC465_002168"
     CDS             1767..2354
                     /locus_tag="PC465_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HDF2649462.1"
                     /translation="MKNLKKILIITGCLTLISTSLVFANTTTDVDTSKDDDSIISSCT
                     ITGYEFTYENAPQSVKFDYEKKCEALNIKPSKNDIIFVNKDSIDANDVENYVEPKAYI
                     IRYKKGYVFEVTGPKSYTLNVSNTVVGYNRVESGNPVHLVQLLCRTLDGSSIDDDSEF
                     GPATYNAVKSLQGRLGLTRDGIVGRSTWDAAGRRL"
     gene            complement(2550..3462)
                     /locus_tag="PC465_002169"
                     /pseudo
     CDS             complement(2550..3462)
                     /locus_tag="PC465_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3965..4342
                     /locus_tag="PC465_002170"
     CDS             3965..4342
                     /locus_tag="PC465_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2649463.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDATVTSKDVIEVMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTVIVKHKDYLSFETKDFLSNIHDDSLKSLISALH
                     DDENIGKDTLDFLESYFDNLKNE"
     gene            4335..5369
                     /locus_tag="PC465_002171"
     CDS             4335..5369
                     /locus_tag="PC465_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="HDF2649464.1"
                     /translation="MNNYMLYVFDNLIKTTIVCSFGICLLLFLKIYFFKRFSKRFNYY
                     IWLVIVFRMLLFLFNYTVMYEVKDPKENTVGNNITQIDISIDNDFMLYLVYLWLFVTI
                     AIAVYTFIEYTKFKNLVVDVSYDIEDNDVNCIYKNLLKELDIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYTYSKDELTWILKHELMHFKNKDILIKFLVLSVKIMYWFNPLVYI
                     MSNKVNLDCELCCDESVLTDCSLKDKKAYALALIKSIKLSKNYNSGILTTEFNKTNLE
                     KRLDSIIKKKGKSGILMLLILFTLFSVTYFNFESISFDNSNYLRNIGILEKTGADLKE
                     EDDISMRVVN"
     gene            5420..6022
                     /locus_tag="PC465_002172"
     CDS             5420..6022
                     /locus_tag="PC465_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HDF2649465.1"
                     /translation="MKSLKKILIVTGCLTLISTSLVFASTNNDVNVSKSNEEQTTNSF
                     TITGYEFIYENAPQPIKSDYEKKCKELNINPSKDDTIFINEKFIDSYNINIDDYNIEP
                     KAFIIRYKKDLNRFDVTGPISYSVNINTTVVGYGHVEKGNPVHLVQLLCQQINGSDID
                     PDSKFGPATYNQVKILQGRLGVTKDGVVGKATWQAAGERY"
     gene            complement(6107..7129)
                     /locus_tag="PC465_002173"
     CDS             complement(6107..7129)
                     /locus_tag="PC465_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF2649466.1"
                     /translation="MNYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSS
                     FIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMSSPIFAAPVSGTILNMGGKVSEK
                     EYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNRGNGIVFIKPWNNSKIIEKI
                     RLSEEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTRLPFIIKGIMTVD
                     DALMAVESGASAIIVSNHGGRVLDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDV
                     VKMLGLGADAVLMGRPFVTASFGGGLDGVEFFIEKIRNELCETMILTGCQNVKDIDGR
                     VIWNLL"
     gene            complement(7458..7640)
                     /locus_tag="PC465_002174"
     CDS             complement(7458..7640)
                     /locus_tag="PC465_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649467.1"
                     /translation="MYKDKSDECIHLMTAYIDSISGYYSFIDTQLEDFMMKYGENIVD
                     SNLHSIMMLLCKWGLS"
     gene            7953..8372
                     /locus_tag="PC465_002175"
     CDS             7953..8372
                     /locus_tag="PC465_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3785 domain-containing protein"
                     /protein_id="HDF2649468.1"
                     /translation="MSLYKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILN
                     EAEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYIFSKDGEYVISNISVDYKGL
                     SFNKLSRANKVDNSYIVSVIICENCQDYIVQIENCIV"
     gene            8503..10344
                     /locus_tag="PC465_002176"
     CDS             8503..10344
                     /locus_tag="PC465_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2649469.1"
                     /translation="MEEIDDTILDSMFKLTLNERLLTNNDFIENKIDVVKNLIDCYKT
                     EQNSLMLLKSNFLLALLYGIQGFSEKMKEYILISCKYIDKCLPKDYKFLARFYSQIAI
                     LSLKNEDVNKANLYMDKFNLICDENNFLIEEIIFKSQLIYIKASKCIESSVIIKEIET
                     LYIKIKEINDFNCKKIYFFIIGKIYFLFLDDALIAKVNFLKARKYADLLKDMQVSSLC
                     NIKIGECECSFENYECSMEYFNEVISNKKYRNVNIIQKYRASNNITKILIKTRNYPVA
                     INNLAKSEVYLEKIKNHSLKEVEKFDLFISLAMYYAKSNEKSFEQSICYLDRAKNILN
                     MIKNIEEYIIYDLEIIYHQAKIYYIFGYYDNALNTNKKLLEKSKNAKNYNYVKLAYKS
                     IYLCFEKIQNYEMSMKYFKMYYELKMMYIKARNRNYIDSLNYRHEYIEKEINNMRKVK
                     LDLDKKKYVDHLTSAYNRTFLNDFLEKQEVSEYCTAFMIDVDYFKEYNDTYGHYNGDI
                     ALKNITIIIKKYLKKDMLMIRYGGEEFLILSVCKDYKKSKIFGRKLCRIVKKFLNNNL
                     TVSIGIDTCKNSSIDIKEIIENADKALYKAKESGRNRCLHYHDFKNF"
     gene            10371..12257
                     /locus_tag="PC465_002177"
     CDS             10371..12257
                     /locus_tag="PC465_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2649470.1"
                     /translation="MKRSLIEDLKRNINKIEYDMLTKFYLNLTDLNYILDYHKDLLNT
                     KLEDNSRVYTLYLISLINYIKKDREASYNYLIESLKYIKKLSLKDDSDIISKIYIYLT
                     LSAISIRKYDKVNNFYFSAKKIIRQNHLNELLVLLNMSLCVEISALYQTKTDVIALVE
                     EVSFFKTLKNKALVSRANYIFGRVYLYLFNNFIKSMEYLIECLKLAQENNLYSIEAFC
                     KCIISLCYLESGNNVEAIKYINNVLDVAHSNNSISVTERVSIKIDLIWAYLKEDMNKE
                     AEVILLKTIKLMKVVEGVYKDYLYSFIFLYSAEIELKKDNCSFEKVNTYLILSKNIYK
                     SFGDVFIYNSKLDYIYKLYGDLYIKFGNIDEGISCYIKGLNLVKKSSLNLRKISIFYG
                     LIANGYELKKDFKLAIEYYKSMDWYSDRWEKNNSYKTSQAIHKQYELRQKQESLRLLV
                     DDNKKLENDILKDGLTKLYNRRYLEQQLDLFNGTRDKNMVAILVDIDCFKSYNDNYGH
                     LAGDKVIVKVTDIIRSVFIDITEHIIRYGGEEILILVDSIESIGVEEIDNIELYIKRV
                     FKLLEFEGIEHIYSKIKNYITISAGVSIKRCHSRKDVEILIEDADKNLYKSKKAGRNQ
                     YIII"
     gene            12265..14265
                     /locus_tag="PC465_002178"
     CDS             12265..14265
                     /locus_tag="PC465_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2649471.1"
                     /translation="MILLRKKIGIIASDIELKERIEELYREDVENGTIIIDILNLDLM
                     ENQGRILVEKGAQAIIGRGGGYSLVIDTVNVPVIPMNMKSTDLLRAIEIAKKYSKKVV
                     LILGDNEVSFDYVGWRNVISTEITEEWFESKYEIRSKVVKYIDQKDEVVIVGGGLACS
                     FARQYGIDSVFATASDESIREAVEYCKKLLDTLGEEKFNNEVLRNILDGIKDGVIAID
                     SNGSIILYNESAKNMLKVERKCALNKYILDVFPKMEWMLDCLHEKEDVEDRKIRNINN
                     LIVNTRTTLIKVDNSTYGVLGIIQDITKLQNLERKIRFDLNQKGLYARYTFDDFLFKD
                     KLTKEFIEEAKKIGKSDYTTLLYGESGSGKEIIAHSIHNISKRKDRPFVAINCATIAE
                     NLLESELFGYEEGAFTGARKGGKRGLFELAHGGTLFLDEINSLSFNIQTKLLRVIEER
                     QIMRIGSDYIIPLDIRIIAATNESLTEKIVMGTFRADLFYRLSSLEINIPPLRDRRED
                     IIPLFNNFVNEVLKDDGLNGINSIDENFVLTKDEMDKLYNYSWPGNVRELKTIAQKYV
                     VTGKIKLRQDRDFKTKKLLPNSEVDKFNSETTASVEVQDESINISKINDGKISIDIKE
                     VNKYVEEKIISMLFAQGLSKNEVAQVLGISRTSLWKKYNKNI"
     gene            14527..15786
                     /locus_tag="PC465_002179"
     CDS             14527..15786
                     /locus_tag="PC465_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2649472.1"
                     /translation="MSQSMVGKHAMWPKENDVIFSISGRAQAAEKAFGMDNVINATIG
                     ALMDDSGKLITMKTVYEEYKVLDNCEIGAYAALEGQPDYLEAVKKVFFRDYLPEGHIR
                     VLASPGGSGAIKLAVWNYTNEGDEVLTSDWFWSPYVSIAEEANRKVVNYQLFDENRRF
                     NFESFKEKFVNIAEKQGRVFTIINTPAHNPTGYSVADDEWDKILDLSKEVAKDKDKKI
                     IFFVDSAYIDFAGDDDVCRKFFKKFSNLPENVLVLVGFSMSKGFTAYGMRMGAIICIS
                     SSEDVAEEFHYSCVHSCRANWSNCNRSAMAVLSNIVNDPKKFKEYEDEKEIYKNMLTR
                     RADVFVKEAERVGLEILPYIAGFFVSIPCDNPKEVCEELTKHNLFAVPLKMGLRFAVC
                     AVSEDKCKKAPSIIKEALESLEVKINN"
     gene            15847..17634
                     /gene="iorA"
                     /locus_tag="PC465_002180"
     CDS             15847..17634
                     /gene="iorA"
                     /locus_tag="PC465_002180"
                     /EC_number="1.2.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="HDF2649473.1"
                     /translation="MKQLMTGNEAIARGAYEAGVKYASAYPGTPSTEILENIATYKDA
                     IVAEWAPNEKVALEAAIGGSIAGARTMASMKHVGLNVAADPIFTYAYTGVNGGMVLIT
                     ADEPGMHSSQNEQDNRMYAKFAKIPLFEPSTSQEAKDMIKEAFEVSEKYDTPVLYRVT
                     TRLCHSKGLVECYDREEVEIKEYVKNAKKMVTVPANAQIRRGVVEERMEILKKFSNET
                     DLNYYEINDTKIGVIASGMCCNFAKEVFGKNASYMKLGFTNPLPYEKIKEFAEKVDKI
                     YVIEENDPFIEEQIKAYGIDCIGKDVIPPYGEMTPDVLRKAIFGKTNDTIEYKSELVT
                     PRPPSFCAGCPHRGFFYELGKRKNLIVGGDIGCYTLGFAPPYNGIDYVVCMGSAFGTA
                     HGAQKVLNMKDDNEKRLVGVLGDSTFFHTGINGLLDVVYNRGNSISVILDNRITGMTG
                     HQENPGSGYTLQGAKTKEVDIEGLVKACGIEHVRVINPNNLKEVNEALDWALAIEDEP
                     SVIITRWPCVLKKFSKEDIEEFNNPFKTKCKVDHDKCIGCKLCLKTGCPALSFDKENK
                     LSNIDRNQCVGCGVCAQVCPKQAIVKEEK"
     gene            17636..18211
                     /locus_tag="PC465_002181"
     CDS             17636..18211
                     /locus_tag="PC465_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HDF2649474.1"
                     /translation="MTKSILLVGVGGQGTILASKLLTMGLMEAGYDVKMSEIHGMSQR
                     GGSVSSQVRYGDCVHSPVIEIGGADILVSFEKMEALRWFNYLKPEGKALVNNHRIDSM
                     TVLIGGAEYQESDIDAELSRLNAKVINAADKAEELGNSKIMNVILLGCLVKSMQLESI
                     DWEKIISENVKPKFVELNIKAFHEGMEMVSK"
     gene            18264..19334
                     /gene="buk"
                     /locus_tag="PC465_002182"
     CDS             18264..19334
                     /gene="buk"
                     /locus_tag="PC465_002182"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HDF2649475.1"
                     /translation="MTYRILAINPGSTSTKIAVYDGEEQILVKTIDHPAEEIAKYNTI
                     QDQFEMRKEAVLNILKENSIDLKSLSAIVGRGGVLPPVKSGAYLVNEEMIDVLRHRPV
                     LEHASNLGAVVAHAISEPLGINSYIYDSVAVDELIDVARISGLCGMDRSSAGHALNTR
                     AMALKYAKDKGKDYKSLNLIVAHIGGGVSIYLHEKGRMVDMLSDDEGPFSPERSGRVP
                     ATKLVAACYSGQYSEREMTKKIRGKGGIVSYLNTVDAREVEKMIAEGNEEAKIIYEAM
                     AYQLAKGIGELATVVDGKVDAIIITGGIAYSEMFTSMVKKKVEFIAPVEIMAGENELE
                     SLAFGTLRVLNGEEEARIYSEN"
     gene            19552..20253
                     /locus_tag="PC465_002183"
     CDS             19552..20253
                     /locus_tag="PC465_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649476.1"
                     /translation="MGKISLKSMIRLFSGFFIFAISSVLMINAHVGLMPWDVLHQGLS
                     IKLGITIGQASIMVGVVIVILDAVFGENIGWGTLLNMTFIGIFIDLVIFSGVIPHASN
                     TYIGVFMVVIGIILAAIASFLYLGVCLGSGPRDGLMIALQKKTNKSVRLVRTILEILA
                     LVVGWLLGGSVGIGTLVSALGLGYVLQIVFRIFKFDTKLLKHRFIIDDIREWKEKKSN
                     EHKCKSSIVIKNEQN"
     gene            20313..20819
                     /locus_tag="PC465_002184"
     CDS             20313..20819
                     /locus_tag="PC465_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HDF2649477.1"
                     /translation="MELWDLYNADGIKTGNVIKRGNSIEEGYYHLAVEVWILNSNSQI
                     LIQKRSKSKKTLPNMWGMTTGCIVSGEDSLEGAIREAKEEIGIDITKDEMKVFRSMIH
                     EDTLWDVYLVKKEYDISKAILQEEEVSDIKWVSTDEIRQLLKEGLFFEYPEIYELLYE
                     IDNNKLNI"
     gene            20994..22016
                     /locus_tag="PC465_002185"
     CDS             20994..22016
                     /locus_tag="PC465_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF2649478.1"
                     /translation="MEDNKGLARDSSKYKIVSISVVVIILITFWYMLNMVLLTFIMTF
                     IFYNLLVATRKRIKKFSSLNIPDSLIIIVLYALFAILLVLISYAVVPIIIVQLTELSR
                     VFSDFDVNQFAQSLGPKLYPIVSKLDFNKYISQAGLLIASTATKVGSFGVNILLAFLL
                     SLLLLLEKNEIKNFGDKLSDSKISFIYNSLVFFGKSFVKNFGEVMKVQVMIAFINSVV
                     SMIFLGFMGFPQIWALGFMIFVLGLIPVAGVIVSLIPLTVIAFNTGGITKVFGVLLMI
                     CIVHAVETYILNPKLMSNRTKLPVCFVFIILLVGEHYLGVWGLLIGVPIFMFLMDILG
                     VKFTSR"
     gene            complement(22163..22471)
                     /locus_tag="PC465_002186"
     CDS             complement(22163..22471)
                     /locus_tag="PC465_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HDF2649479.1"
                     /translation="MKNNNLNCAATNCAYNTSGYCYAGSIKVDGMQATTTENTYCASF
                     EDKYTSGITSRSNETNQVDTDNIHCEAVKCKYNKNELCKAEKVHINERNASCETFEMK
                     "
     gene            complement(22531..22959)
                     /locus_tag="PC465_002187"
     CDS             complement(22531..22959)
                     /locus_tag="PC465_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649480.1"
                     /translation="MNNKLHELEKNLPETSCSFCTHLSFKGPSLDYRYDIRCVISDTK
                     PDFRGCCEYFEPEYTELNTGDLDNLYINFLETCLKVNYNDYINSMYWKLFKERTLLEN
                     NFKCSICGSTENVDVYHVNKNLGRETSKDVVVKCDKCNCK"
     gene            complement(23182..24639)
                     /locus_tag="PC465_002188"
     CDS             complement(23182..24639)
                     /locus_tag="PC465_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HDF2649481.1"
                     /translation="MTTFLIGLAILLIGGALYGAYCEKVFGPDDRKTPALAQSDGVDY
                     VPMKKWKNSLIELLNIAGTGPILGPIQGILFGPIAFILIPIGCVFGGALHDYMSGMIS
                     IREKGAQMPSLISRFLGNKVFQVYNIFLCLLMLLVGAVFIYTPGDLVVTQILNMKSTI
                     NNPVVWIVYGLIFLYYLCATLFPIDKIIGKVYPIFGAILLLSAAGVGIGIFTQGYDLA
                     NLSLANWKGIHPDGIPLIPTFFVTVACGIVSGFHSTQATLIARSVSNEKEGKTTFYNM
                     MILEGLIAMIWAAAAMGIYNKGIPKELVGSPDVIGLVARDLLGSIGGIIAIIGVIVLP
                     ITSGDTALRSLRLMLADYFHYDQKEKKHRVILSICIFIPVIAILIFAKLSASGFNILW
                     RYFSWSNQTIAIFAFAMITVYLIIKEKNYIISLIPGMFYSFVIFSYIFNAQIGFNLNI
                     NISYVLAAIFTVLYAILTVRSGRKLKSKADTKLAD"
     gene            25057..25971
                     /gene="nadA"
                     /locus_tag="PC465_002189"
     CDS             25057..25971
                     /gene="nadA"
                     /locus_tag="PC465_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HDF2649482.1"
                     /translation="MDKDLTYQIKELKKEKNAIILAHFYQPPEIQELADAVGDSYYLS
                     EIARDCKEEVVVFCGVRFMGESAKILSPEKTVLMPVSNAGCAMADMVDEEGVIKLKQQ
                     YPNALVVCYINSTAKVKAHCDVSVTSSSAIKILENIDNKEIIFLPDKNLGGYIAEQFP
                     DKNFIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGII
                     KYATNSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYSTLKN
                     MENEVIVEDEIMEKALNSLLNMHKLAEG"
     gene            25984..27285
                     /locus_tag="PC465_002190"
     CDS             25984..27285
                     /locus_tag="PC465_002190"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HDF2649483.1"
                     /translation="MNLEQDVLIVGSGVSGLYCALNLDKSLNVLVVSKSTIENNNTYL
                     AQGGISTARNIDDIESFVEDTMKAGQYKNRVEAVQVLADESIENVGQIVEYGMPLDKE
                     NGEIDYTREGAHSVNRIVHSKDNTGEVVFKTLLKEAKTRENITLIEDAYLLDILKDGN
                     KCIGARIFKSKKEIHVFSKIVVLATGGIGGLFKNSTNQRHLTGDGIAIALRNNIKIEN
                     LEYIQIHPTAFYEENNEGRRMLISESLRGEGAKLLNKNKERFVDELLPRDVVSKAIFE
                     QMEKDKLPYVYLDATHLDSEYLINRFSFIYNECLARGTDITKECIKVSPAQHYFMGGI
                     HVDLDSKTSMENLYAVGEISCTGVHGANRLASNSLLEGLVFSKRAAKNINSVIDNVKV
                     KFIDVPDMDIDIEQVKKENKILVIKEIERTSEDFGDELFDY"
     gene            27266..28102
                     /gene="nadC"
                     /locus_tag="PC465_002191"
     CDS             27266..28102
                     /gene="nadC"
                     /locus_tag="PC465_002191"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HDF2649484.1"
                     /translation="MNYLIIDRMIQDALIEDVPSEDITTNSIVDENSKSTVDLICKQD
                     GIIAGLGVFKRVFEILGDVDVKLYKNDGDRVKNREKIAVLTGSTRNLLVGERVALNYL
                     QRMSGIATITSRYVEKLEGTNTKLLDSRKTIPNLRILDKYSVKVGGGCNHRFNLSDGI
                     LLKDNHIGAAGSVKKAVELARKNTSFVRKIEVEVETLDMVKEAIEANADIIMLDNMSL
                     EMAKQAVDIINGRAIVEFSGNVNLDTIEDIGKIGVDVVSVGALTHSVKALDISMKNLR
                     NI"
     gene            28358..28690
                     /locus_tag="PC465_002192"
     CDS             28358..28690
                     /locus_tag="PC465_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HDF2649485.1"
                     /translation="MKVAYIFSSTNTHKILDKMIIPQLEQGTHGVDVLGMFFFMDNTL
                     FLSKGNPVGERLSKLHEKTDMIIMACDQCAIERGIENNLVDGATIGCFPNLYACLGSA
                     GVDQVITL"
     gene            28852..29037
                     /locus_tag="PC465_002193"
     CDS             28852..29037
                     /locus_tag="PC465_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649486.1"
                     /translation="MSEKYADKLEIKLYQAGKDFSYIKKYGIITKGTLIINQKKKYDR
                     LNKDTIERAIVEAINNN"
     gene            29064..30149
                     /locus_tag="PC465_002194"
     CDS             29064..30149
                     /locus_tag="PC465_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDF2649487.1"
                     /translation="MNILEIVLNGVKDTIVASIVTLNGASGWLMISFILAGVLHNVLT
                     PRRFQKQLGNKKFSSLIKSTISGMFLPICSCGVIPLGISMYYSGAYLGPVLAFMTSTP
                     IINPIAVVLCLGLLGPKVTIIYLIAGFLVPFLVGFLGNCFGKEELSLHNDSEEEVIEL
                     EEEKRSFMGNMIDGLKWSFGELALTISKYVVMGMVFAGFITTIFPNSIIQKYLGNPGL
                     LSLGSIAILACVMYVCAVGHIPFIAALVASGASPGIAITFLIAGAATNLPELISMFKL
                     IGKRTVIIYSVTLTLSSIIIGYITNLLLVNNNSVNLDATNSSIQLANKLMLNIPDSFE
                     YVCTILIILFAFKSIIPKMKEVIGNHA"
     gene            30142..30600
                     /locus_tag="PC465_002195"
     CDS             30142..30600
                     /locus_tag="PC465_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649488.1"
                     /translation="MLKKIVIISCIVVVLIILSKIVDDNIKEDASIPNVNKETLEYFR
                     KNYKEDIITCAEEDLNNDGKKDLVVIYKKSNNSNEMVVVVSDKNSHYITKPIPAPIEN
                     QTITFKNIDDKAPIEVIVSGSKNGNVGYAIYRVEGKKFVDLFGEDMDKCC"
     gene            30629..31720
                     /locus_tag="PC465_002196"
     CDS             30629..31720
                     /locus_tag="PC465_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2649489.1"
                     /translation="MKLSKKIQALILFGVMGTSILTGCSSKPKEKEEAKTGKDDYTIT
                     VGYYNCDHMTAGPVAESAGIYKDLGLNVKTVGNGKVPEAMAAGKMDAGYIGTKGLVGA
                     IPKGSPITIAANNHTGGSEYLIVSKDIKEPKDLIGKKIATDMSDFLWTSDYGPETGLP
                     TDPSKYEVVNMDSDKDKYLALKTGKIQAFTSCDPWGSVAENDGAGKIIASTQYKEKAN
                     GKEYNCCSFSLNKNFIKEHPDLAKKLVLAHTKAIEYIYTNPAEAAKIFAKYYNVEEEV
                     ALRTIYKKTVGEGRTLTWKVTGEEYKNNLQMYKDLKALDDIPKYEDTIDTSLLDSCGA
                     DDFDKFIKEKVNPEFPEGMSYEDWKAKVL"
     gene            31725..31949
                     /locus_tag="PC465_002197"
     CDS             31725..31949
                     /locus_tag="PC465_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649490.1"
                     /translation="MENMKNIIILFIIILGSIFIIFFNFEDKEEIKGKLRIGVSDDTS
                     GFVINYMVNRDYFENIKVSDIMDIFTINDC"
     gene            31959..32522
                     /locus_tag="PC465_002198"
     CDS             31959..32522
                     /locus_tag="PC465_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649491.1"
                     /translation="MQWALSSEEIDIAIICKDAAKQYVNVNSGFEIVGTVVQNSDIFL
                     LSDNNPEKIGVIQNRDYQSELVKKYYKNVEVAPLLGTALAYGLESNLVDGVVIDCIKS
                     IGLEGKRKSTTKLGDYDTYVLVVNKEFKKSKAYSDFITLYNKSVDALKNKATFKKVLK
                     EYRNIRNIDMEEISNWKLKFLKIKAID"
     gene            32483..33112
                     /locus_tag="PC465_002199"
     CDS             32483..33112
                     /locus_tag="PC465_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2649492.1"
                     /translation="MEIKISKDKSDRLTKKKTDGSMDILYKIILLVIIFLVWHFAAKD
                     IGSSLLLPMPVDVIKGFFFCVTDAETVTNLFITLQRVLKGFMYALLFGLPIGFIMGFS
                     KTFERVLSPVVDSVRQVPIMAWVPLTIVWFGIGDGPTIFLIAFSGVFPIILNTIQGVR
                     AISKDYYNAARSMGASPIVIFTNVIVPASLPDILTGSRIAISTGWMSVI"
     gene            33289..34041
                     /locus_tag="PC465_002200"
     CDS             33289..34041
                     /locus_tag="PC465_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2649493.1"
                     /translation="MKLSVRDINKTFVNNRVHTKVLEDISMDIDDGQFVCLLGPSGCG
                     KTTLLTIIGGFQKSERGDVFINDKRVKKPGIDRAFIFQNYALFPWKTIRGNVLFPMKQ
                     QKIPKEKREEMLEELLVMSDLKGKEKLFPHQLSGGMKQRVAMIRALACNPEVLLMDEP
                     LGAVDFQMRQNLQEELERIWIKKKITALMVTHDVDEAVYMSDRVIVMSRDKGRIIDDI
                     NIDIPRPRIRGSQKYEEYKNKLTDTLSKCYEV"
     gene            34054..34539
                     /locus_tag="PC465_002201"
     CDS             34054..34539
                     /locus_tag="PC465_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649494.1"
                     /translation="MSQIEKYNSLNNTQQKIRISIMDMIIDKGSSVTLQEVTEYVSKK
                     LNIEKEYIERTLQYFIYKNIMVVDGNSINFIYPVSALPTNHKVTLRDNRSFSAMCAID
                     AIGTSCTFNQDIKINSICSATGKEIEVIIKNEKIEYVNNPNLRVLHINLDKHLNWAAS
                     C"
     gene            34546..34695
                     /locus_tag="PC465_002202"
     CDS             34546..34695
                     /locus_tag="PC465_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649495.1"
                     /translation="MNFFWTKSDFDAWTNEAGLSDDEDIYCLDINEAIVESYKIFKLK
                     QKVLS"
     gene            complement(34832..35653)
                     /gene="yidA"
                     /locus_tag="PC465_002203"
     CDS             complement(34832..35653)
                     /gene="yidA"
                     /locus_tag="PC465_002203"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HDF2649496.1"
                     /translation="MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGR
                     PLPGVKELLNQLNLTDEGDYVICFNGAIIQEVKSEKIIHDVEMSLDDFDFIYNNVCKK
                     YKTKIHINTMTNLITPNETPGKYTLHEAKLNNIEVKYIQKDKIDESIKICKIMIVDEP
                     ERLEEIIQQLPKNLFNKYTIVRSAPFYLEFLGKTTNKGTALKTLCMNLNIPIENAIAV
                     GDEENDQHMIKYAGLGVAMGNARNSIKEIADYVTDTNNENGVAKVINKYILNKAI"
     gene            36146..37840
                     /locus_tag="PC465_002204"
     CDS             36146..37840
                     /locus_tag="PC465_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HDF2649497.1"
                     /translation="MKFSEFKYERPNYNSMKKEFLSCVEDINNSRNYKEQQKNIHKIN
                     LLRNKIETLSNIASIRYSTDTFNKFYKEEKNYWDEYMPLYEELNSYFYNAIVNSKFKY
                     DLIKEFGEQFFTIVEYSLKSFSKEIISELQEENKLCSEYTRLLASAEIMFDGKIRNLS
                     GMGKFMYSKNRKTRELANKAYYNFFEENETKFDDIFDKLVKLRDKMSKKLGFEDFVEL
                     GYVRMMRSDYREYMIKNVRKQVLKYVVPMANELYEKQAKRIGLEYLSYIDEGVEFLTG
                     NASLKGDSRYIIQNGKRMYSELSKETNEFFDFMLENELMDLETKKGKGAGGYCTYIPD
                     YKSPFIFSNFNQTADDIDVLTHEAGHAFQLYMSRWIDMPEINFPTLDSCEIHSMSMEF
                     ITWPWMDLFFKEDTDKYKFTHLSSSIKFIPYGVIVDEFQHYIYKNPNVDKSKRKEIWR
                     FLEKIYLPHRKYGDNSFLERGCWWFKQGHIFKNPFYYIDYVLAQICALQFWKKMIQDR
                     DAGWKDYINICKVGGTKSFLDIVSMGNLYSPFDDGCIESIIGDVKSWFDEINDSKL"
     regulatory      38172..38282
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            38386..38757
                     /locus_tag="PC465_002205"
     CDS             38386..38757
                     /locus_tag="PC465_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdX family protein"
                     /protein_id="HDF2649498.1"
                     /translation="MIIITNNPKVKEEVQGREVLFKDTTYIGILEASRDLIHEGYELL
                     SHPLYGSVKPNETPYRTVILKKGNRLDINSLTLIEEAIITASKFQNNKKTPKWTESVQ
                     DDFRVIDYDIFYNTIQRMQYE"
     gene            38852..39799
                     /gene="trxB"
                     /locus_tag="PC465_002206"
     CDS             38852..39799
                     /gene="trxB"
                     /locus_tag="PC465_002206"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDF2649499.1"
                     /translation="MENVYDLVIIGSGPAGLAAGLYGARAKLKTLILEKDKTGGQIVI
                     THEIANYPGSVPNATGPSLIARMVEQCKEFGAEMLRDNIVDTELDGDIKVLKGEKAEY
                     RAKAVIIGTGATPRKIGCPGEKELTGKGVSYCATCDADFFEDFEVFVVGGGDSALEEA
                     MYLTKFARKVTIVHRRQGFRCAKSVEEKAKANPKIEFLLDTVIEEIKGDGILESVVFK
                     NKVTGETHEYFADEEDGTMGVFVFVGLDAQTDLFKGKVDMDEKGYIITDEDMRTNIPG
                     VFAAGDCRSKTLRQVVTATNDGAIASIVAEKYIDEKFGN"
     gene            39884..40201
                     /locus_tag="PC465_002207"
     CDS             39884..40201
                     /locus_tag="PC465_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HDF2649500.1"
                     /translation="MLDLDKATFEEEVLNAEGFVFVDFWSEGCEPCKALMPDVHKLAE
                     TYGDKIKFCKMDTTKARRLAIKQKVLGLPTMAIYKDGEKVDEVTKDDATVPNIENMIK
                     KYL"
BASE COUNT        15828 a         4215 c         6827 g        13353 t
ORIGIN      
        1 attagatatt actctagttt attttaaaaa aaagtattat aatattcctt gtgtgaaaat
       61 ataggaattt ttattaaaca gttttaatgt gtaaataaca ttctacacta ttgtaattaa
      121 atatgtaaaa agtaaaatat ttaaatagat atattttaaa atctaacttt taatattgta
      181 aaaaaattag aaatttaaca aaaagtacaa aaattcacat ttttttcata aagtgtttga
      241 ctaaaaaatt cacatgttgt agaattaagg tagcaggagt tttgagggag gtgtaaataa
      301 tgataagaaa aataccacaa gcagaactaa aagtaatgaa attcatttgg aaagtagatg
      361 ttacagtgac atcaaaagat gttattgaag ctatggaaca aaaatatggc tggaaacaaa
      421 ccaccacact gacactttta tctaggctgg taaaaagagg attcttagat gctcaaaaaa
      481 tagacagata tacacattac acaataagag taaaacacaa agattattta agttttgaga
      541 caaaggattt cctaagtaat atacatgatg actctttaag aagcttaatt tcagcattac
      601 atgatgatga aaatataggt aaagataagc tagattttct agaaagttat tttgataatt
      661 taaaggatga ataattatat gctatatgtt tttgaaaatc ttataaagac aactattgta
      721 tgtagtcttg gtatttgtct attattattt ttgaaaagat atttatttaa gaagtttagt
      781 aagagattca attattatat ttggttgata atagtcttta gaatgttact ttttctattt
      841 aattatacaa tagtatatga agtaaaagaa cccaaagaaa atgcagtaag aaataatatt
      901 acacaaattg atatttctac agataataat cttatgctgt atgtagctta tttatggtta
      961 tttgtaacta tagtcattgc agtttataca tttataaagt atacaagatt taaaaatcta
     1021 gttgttgatg tatcttatga tattgaagat aatgatataa actgtatcta caaaaacttg
     1081 ttaaaagaat taaatataaa aaagaaaatt gaattaagag gttctgatga attggtaagt
     1141 ccagcaggca tgggattatt taaatcttac atattcttac cagactatcc ttatagtaaa
     1201 gatgaactaa cttggatttt gaaacatgaa ttaatgcatt ttaaaaataa agatatttta
     1261 ataaagtttt tagttttgtc tgttagaata atatattggt ttaatccact tgtatatgta
     1321 atgagcaata aagtaaatct agattgtgaa ttatgctgtg atgaaagtgt tttgattgat
     1381 tgttctttaa agaataagaa ggagtatgca ttagcactta taaagtcaat taaacttagt
     1441 aagaattata atagtggtat tttaacaaca gagtttaata agacaagttt ggaaaagaga
     1501 cttgacagta ttgttaagaa aaaaggtaaa agtggaatat tggtgttatt gattttgatt
     1561 acattatttt cagttacata ttttaatttt gaaagtatta gttttgataa ttcaaattct
     1621 ttaaggaata tggggatttt acaaaaatca ggagtagatc ttaaggaaga agatgatatt
     1681 agcatgagag ttataaatta atagattaat atatgtaatg aaaaggtata ttgtcatatt
     1741 attaataaat taggaggaat tatgaaatga aaaatttaaa aaaaatttta ataattacag
     1801 gttgtctaac tctaatatct actagtttgg tatttgcaaa tactactact gatgtagata
     1861 catcaaagga tgatgattca ataataagtt catgtactat aactggttat gaatttacat
     1921 atgaaaacgc accacaatct gtaaaatttg attatgaaaa aaaatgtgaa gcgctaaata
     1981 taaaaccatc taaaaatgat ataatttttg ttaacaaaga ttctatagat gcaaatgatg
     2041 tagaaaacta tgttgagcca aaagcatata ttattagata taaaaaaggt tatgtttttg
     2101 aagttactgg acctaagagt tatacattaa atgtaagtaa tactgtagtc ggatataatc
     2161 gtgttgaatc aggtaatcct gtgcatttag ttcaactttt atgtagaacc ttagatggtt
     2221 caagtattga tgatgatagt gaatttggac ctgctacata taatgcagtt aagtcacttc
     2281 aaggaagact tggattaaca agagatggaa ttgttggaag aagtacttgg gatgcagctg
     2341 gaagacgtct ttaaaaagaa agctattgca cagataattt taaattgctg aatctgtaaa
     2401 catttacatg tattctttaa acaaaaattt attttttaag tgataattaa atttttacta
     2461 atagggctat ggctttaaaa atcatagcct tattttgata tatttttcat ttttgcaaaa
     2521 actattaacc ctttaagaaa aattcttgtt tattttgaaa aatttctttc ttcaaaataa
     2581 atacttaaat gagctaaaat ttgagcacaa tttctaattt tctgagtcca tttttaagaa
     2641 atatacatgg ttgttaagta tagtgatgtg tgcaaataat tatccaaagt aaaaatagat
     2701 ttcaatttag taacttttct taataatcta ttctaacttt acattgaatt tgtagtatat
     2761 atcgatgtat ttatttcttg aggatactta aaatatgtta ctaattcatt ccaattgttt
     2821 caccaacctc ttaatactat tgtatattga ttgtactatt tcatattatt aaaacccctt
     2881 ttatgccttc taagttaata catatagcta tatatactgt tttgtttatt attccacctc
     2941 acttctaact ttataatgta tagcatctat aaatacaatt gaataaatta tattaagagg
     3001 tctaagttac catttatgag ctaaaggaat aactttatca gtagttttag ttattagtga
     3061 atgagataat atcaattcca taagtacttt taagatgact taatatattt tgagtagaca
     3121 tgccttttaa gtatattcca atcacttgat tttttattcc taatatatca ttttcatagt
     3181 ttctaattac ctttagttca aaatcttcat ttcgctttct tgaaatattt aaagttattt
     3241 ctccaaaatc tgatttaata tttttatttc tatatccatt tctagagttt ttagtatttt
     3301 tgttcttatt atcgttctat cataacctaa aagttcatca agctccgctt ctaacattta
     3361 atggattgta ctttaaaata aatcttttag tatatcttga atatctgtaa ttgttttgac
     3421 atcatattct tcaataaatt tttttaatat tttagttttt attaaacata aaaagtgtac
     3481 atcttccttt gtatagtagt gatgttttaa ttattataac tttttagaag aatacaaact
     3541 ttattttaaa gacactcaaa atggtgtttt tataccttta tttgatatgt ataattttac
     3601 ttataacata aacttatata aaacagatat tttaataaca caaaggtaca attaggagat
     3661 tgttaaaatt tattagatat tactctagtt tatttaaata aaagtattat aatattcctt
     3721 gtgtaaaaat ataggtagtt ttgttaaata attttaatgt ggaaataaca ttctacacta
     3781 ttataattaa atacgtaaaa agcaaaatac ttgaataact atattttaaa atctaacttt
     3841 taatatttaa aaaaattaga aaattaataa aaagtacaaa aattcacatt ttttcataaa
     3901 gcgtttgact aaaaaattta catattgtag acttaaagta gcaagagttt tgagggaggt
     3961 gtaaatgatg ataagaaaaa taccacaagc agaactaaaa gtaatgaaat ttatttggaa
     4021 agtagatgct acagtgacat caaaagatgt tattgaagtt atggaacaaa aatatggttg
     4081 gaaacaaacc actacactaa cacttttatc taggttagta aaaagaggat tcttagatgc
     4141 tcaaaaaata gacagatata cacattacac agtaatagta aaacacaaag attatttaag
     4201 ttttgagaca aaggatttcc taagtaatat acatgatgat tctttgaaaa gcttaatttc
     4261 agcattgcat gatgatgaaa atataggtaa agacacgcta gattttttag aaagttattt
     4321 tgataattta aagaatgaat aattatatgc tatatgtttt tgacaatctt ataaagacaa
     4381 ctattgtatg tagttttggt atttgtctat tattattttt gaaaatatat ttttttaaga
     4441 ggtttagtaa gagatttaat tattatattt ggttggtaat agtctttaga atgttacttt
     4501 ttctatttaa ttatacagta atgtatgaag taaaagatcc caaagaaaat acagtaggaa
     4561 ataatattac acaaattgat atttctatag ataatgattt tatgctgtat ttagtttatt
     4621 tatggttatt tgtaactata gccattgcag tttatacatt tatagaatac acaaaattta
     4681 aaaatctcgt tgttgatgta tcttatgata ttgaagataa tgatgtaaat tgtatctata
     4741 aaaatttgtt aaaagaatta gacataaaaa agaaaattga gttaaggggt tctgatgaat
     4801 tgataagtcc agcaggtatg ggattattta aatcgtacat attcttacca gactatactt
     4861 atagtaaaga tgagttaact tggattttga aacatgaatt aatgcatttt aaaaacaaag
     4921 atattttgat aaagttttta gttttgtctg ttaaaataat gtattggttt aatccacttg
     4981 tttatataat gagcaataaa gtaaatctag attgtgaatt atgttgtgat gaaagtgttt
     5041 tgactgattg ctctttaaaa gataagaaag catatgcgtt agcacttata aagtcaatta
     5101 aacttagtaa gaattataat agtggtattt taacaactga atttaataag acaaatttgg
     5161 aaaagagact tgatagtatt attaagaaaa aagggaaaag tggaatattg atgttattga
     5221 ttttgtttac attattttca gttacatatt ttaattttga aagtattagt tttgataatt
     5281 caaattattt aagaaatata gggattttag aaaaaacagg cgcagatctt aaggaagaag
     5341 atgatattag catgagagtt gtaaattaat agatttttat agtattataa tttattaaca
     5401 aattaggagg aattttgaaa tgaaaagtct aaagaaaatt ttaatagtca cagggtgttt
     5461 gactctaata tctactagtt tagtatttgc aagtactaat aatgatgtaa atgtatcaaa
     5521 aagtaatgaa gagcaaacaa caaattcatt tacaataact ggttatgaat ttatttatga
     5581 gaatgcacca caacctataa aatctgatta tgaaaaaaaa tgtaaagaat taaatataaa
     5641 tccatctaaa gatgatacaa tctttattaa tgaaaaattt atagattcat ataatattaa
     5701 tatagatgat tataatattg aaccaaaagc atttattatt agatataaaa aagatttaaa
     5761 tcgttttgat gttactggtc ctataagtta tagcgtaaat ataaatacca ctgtagtagg
     5821 atatggacat gtagaaaaag ggaatcctgt gcatttagta caacttttat gtcaacaaat
     5881 aaatggttct gatattgatc cagatagtaa atttggacct gctacatata atcaagtaaa
     5941 aatacttcaa ggaagacttg gtgtaacaaa agatggtgtt gttggaaaag ccacttggca
     6001 agctgccgga gagcgttatt agaaaagagg ttgtcgcact aagaaatagg gcgacaacct
     6061 ttttatatag aatatattaa tcagtatctt agagtctaga aatattttac aataaattcc
     6121 atataactct accatctata tccttaacat tttgacaacc agtcaaaatc atagtctcac
     6181 ataactcatt cctaatcttc tctataaaaa actccacacc atcaagacca ccgccaaaag
     6241 aagcagtaac aaaaggtctt cccatcaaaa cagcatcagc acccaatcca agcatcttaa
     6301 ctacatcaac accagtccta actccaccat caacaagtat tgttatcttt ccctttacag
     6361 acttagctat atctggaagt acctcacaag taccaggagt ataatcaagt actcttccac
     6421 catgatttga aacaataatg gcactagcac cagactctac agccatcaaa gcatcatcta
     6481 cagtcataat tccttttata ataaaaggta atctagtgga ttcaaccaat tctctaatct
     6541 catcaattgt tttaggagaa aaaggatttt cttgaaattg attattaata agtccacaag
     6601 catcaaggtc tacaccaact gcaaaagcac ctgcttcttc agacaatcta attttttcta
     6661 ttatctttga attattccaa ggctttataa atacaattcc atttccccta ttatccttca
     6721 atacatctaa attatccagt aaaaaagtat ctacattagt atcgccaacc atagcataaa
     6781 ttccagaatt agaacaacct ctaacaacag gctctatgta ttctttttcg gaaactttac
     6841 cacccatgtt caatatagta cctgatacag gtgcagcgaa tataggagaa ctcatttttc
     6901 taccaaataa ttctatggat gtatctggct ttgaaacatt atgtatgact ctcatattta
     6961 tctttatttt ttctagactt tttctatttt caatgaaaga cgaaccactt cctttaccac
     7021 ccataccagg aacatctcca gcacaagcta atccattaca aattttacat accttacatg
     7081 ttccattaaa gttctctcta gctgatttta gtaagtcatt gtaattcata caaaatctct
     7141 cctttttata atattaaaat tgagtattac tatattgaaa atatcttaat tgtaaatata
     7201 tggatgttat tatgatgagc taaactagat aatacatatt agatattttt tattgttgta
     7261 gatagttaaa ttatatcata ttagacagtc aaattttgaa aaaaactaac ttatttaagt
     7321 atacattttg aaaaaattaa aaaagctata tatagatttt taaagaaatc tatatatagc
     7381 ttttaagttt atgtcaatct tttttgttaa tgaataaata atataggata caatatacaa
     7441 aaaagtttct tgaaatgcta agataatccc catttacaaa gcaacatcat tatactgtgt
     7501 aaatttgaat caacaatgtt ttcaccatat ttcatcataa aatcctctaa ttgtgtgtca
     7561 ataaatgaat aatatccact tatactatcg atgtatgcag tcattaagtg tatacattca
     7621 tcacttttat ctttatacat atatatctcc ccctatatac aatatataaa tttagatacc
     7681 aaatcgtatc atattaaata gttaagtgtg taacatctat gcagttatat atttatatca
     7741 ttatattaat aactaaagtg agttttgaca atagattttg ggaaactgga tgttcaaatt
     7801 gcaaacttgg attttaaaat cattaattaa gatagcgcat aggaatatat gtatacataa
     7861 cttaattata aagattataa acaattactt ttattaactt tatttaaatg gtagaataac
     7921 ttggagatta ataattataa ggaggatata atatgagttt atataagttt atatatgatg
     7981 ataaggaata tttattaaaa gaggagaact gtagtgcttt aataaatgat gaagaaaatc
     8041 cagttcaagg agtaagtatt tcaaaaataa ttgatatact taatgaagca gaagaagttg
     8101 attttgatgt agaatattat caagaagcat gtccattatg tttagaagga gtaaaagaaa
     8161 agaaaaaatt ctttcctttt ttagaatatc acttttatat tttcagtaaa gatggagaat
     8221 atgtaataag caatatatct gttgattata aaggactatc ttttaataaa ctatcaaggg
     8281 caaataaagt tgataatagt tatattgtaa gtgtgataat ttgcgaaaat tgtcaggatt
     8341 atatagttca gatagaaaat tgtatagttt agtgtaaagt atgtcttaat ttaagagaaa
     8401 tttctaaatt gagacatcaa cttttttcaa aaatagtatg gaaaattact aaatttatga
     8461 gataatgtaa gtcggaggtg agttacaata tatagtaaat atttggaaga gatagatgat
     8521 acaattttag attcaatgtt taaactaacc ttgaatgaaa gattattgac taataacgat
     8581 tttattgaaa ataaaattga tgtagtaaag aatttaattg attgctataa aactgaacaa
     8641 aatagtttaa tgttattaaa atcaaatttt ttgctagctt tattatatgg tattcaaggg
     8701 tttagtgaaa aaatgaaaga gtatattttg atttcctgta aatatattga taaatgctta
     8761 cccaaagatt ataaattttt agcacgattt tattcacaaa tagctatttt aagtttaaaa
     8821 aatgaagatg taaataaggc aaatttatat atggataaat ttaatcttat ttgtgatgaa
     8881 aataattttc taattgaaga aattattttt aaatcacaac ttatttacat taaggcaagt
     8941 aagtgtatag aatcttctgt aataattaaa gagatagaaa cgttgtatat aaagataaaa
     9001 gaaattaacg attttaattg taaaaaaata tattttttta ttattggtaa aatatatttt
     9061 ttgtttttgg atgatgctct aattgctaag gtaaattttt taaaagcaag aaaatatgca
     9121 gatttactaa aggatatgca agtatcttca ctatgtaata taaagatagg tgagtgtgaa
     9181 tgttcgtttg aaaattatga atgttccatg gaatatttca atgaagtaat aagcaataaa
     9241 aagtatagaa atgtaaatat aattcaaaaa tatagagcat caaacaacat aactaaaata
     9301 ttaataaaga ctagaaatta tcctgtcgca ataaataatt tagcaaaatc tgaagtatat
     9361 ctagaaaaaa ttaaaaatca tagcttaaaa gaagtagaga agtttgattt atttataagt
     9421 ttagccatgt attatgcaaa aagtaatgaa aaatcttttg aacaatcaat atgctattta
     9481 gatagagcta aaaacatatt aaatatgata aaaaatatag aagaatatat aatatatgat
     9541 ttagaaataa tttatcacca ggcaaagata tattatatct ttggatatta tgacaatgcc
     9601 ttaaacacaa ataaaaaact ccttgaaaaa tctaaaaatg ctaaaaatta taattatgtg
     9661 aagttagcat ataagagtat atatttgtgt tttgaaaaga ttcaaaatta tgaaatgagt
     9721 atgaaatact ttaaaatgta ttatgagtta aaaatgatgt atataaaagc tcgaaataga
     9781 aattatatag attccttaaa ttatagacat gagtatatag aaaaagaaat aaataacatg
     9841 agaaaagtaa aacttgattt agataaaaaa aagtatgttg accatttgac aagtgcatat
     9901 aatagaactt ttttgaacga ttttttagaa aaacaagaag ttagtgaata ttgcacagca
     9961 tttatgatag atgtagatta ctttaaagaa tacaatgata cttatggaca ctacaatgga
    10021 gatattgctc ttaaaaatat aactataata ataaaaaaat atctaaaaaa agacatgctt
    10081 atgataaggt atggtggaga agaatttctg atattatctg tatgtaaaga ttataaaaaa
    10141 agtaaaatat ttggaagaaa attatgtagg attgtaaaga aatttttaaa caataatttg
    10201 acagttagta ttggcattga tacatgtaaa aatagtagta tagatataaa agaaataatt
    10261 gaaaatgctg ataaagcttt atataaagca aaggaaagtg gtagaaatag atgtttgcat
    10321 tatcatgatt ttaagaattt ttaactgttg aaataggatt ggtgatttac ttgaaaagga
    10381 gtttaataga agatttaaag agaaatataa acaagataga atacgatatg ttgactaaat
    10441 tctatctaaa tttgacagat ttaaactaca tcttggatta tcacaaagac cttttaaata
    10501 caaaattaga agataatagt agagtctata ctttatattt aattagtctt ataaactata
    10561 taaaaaaaga tagagaagca tcatacaact atttgataga gtcattaaag tatattaaaa
    10621 aattgtcatt aaaagatgat tcagatataa tatctaaaat ttatatttat cttactttat
    10681 cagctatttc tataagaaaa tatgataagg taaataattt ttatttctca gcaaaaaaaa
    10741 ttataagaca aaatcattta aatgagttgt tggtattgtt aaatatgagt ttatgtgtag
    10801 aaataagtgc tttatatcag accaaaacgg atgtaatagc tttagtagaa gaagtgtctt
    10861 tttttaaaac tttaaaaaat aaagctcttg taagtagggc aaattatata tttgggagag
    10921 tttatctata tttatttaat aactttataa aaagtatgga atacttaatt gaatgtctaa
    10981 aattggctca agaaaataat ttatactcta tagaggcttt ttgtaaatgt ataataagtt
    11041 tgtgttattt agagagtgga aataatgtag aagctataaa atacataaat aatgtattag
    11101 atgttgcaca cagtaataac tcaatatcag taactgaaag agtgtctata aaaatagacc
    11161 ttatatgggc atatttaaaa gaagatatga ataaagaagc agaagttatt ttattaaaga
    11221 ctataaaatt aatgaaagtt gttgaaggtg tatataagga ttatttatat tcatttatat
    11281 ttttatattc agctgaaatt gagttaaaga aagataattg tagttttgaa aaggtaaaca
    11341 cctatttaat tttatcaaaa aatatatata aaagttttgg agatgttttt atatataatt
    11401 ctaaactaga ttacatatat aagttgtatg gagatttata tataaaattt ggtaatatag
    11461 atgaaggtat aagttgttat ataaaaggtt taaatttagt taaaaagagt tcattgaatc
    11521 ttagaaaaat atctatattt tatgggctaa tagcaaatgg atatgagcta aaaaaagatt
    11581 ttaaactggc aatagaatat tataaaagta tggattggta ttctgatagg tgggaaaaaa
    11641 ataattccta taaaacatct caagcaattc acaaacaata tgaactcaga caaaaacaag
    11701 agagtttaag attactagtg gatgataata agaaattaga aaatgatatt ttaaaagatg
    11761 gacttactaa actatataat agaagatatt tggaacagca gttggattta tttaatggaa
    11821 ccagagacaa aaatatggtt gcaatactgg tcgatataga ttgttttaaa agttataatg
    11881 ataattatgg tcatctagca ggggataaag ttatagttaa ggtaactgat attataagaa
    11941 gtgtatttat agatattacc gaacacataa tcagatatgg gggagaagaa attttaatat
    12001 tagtagattc tatagaatca atcggtgttg aagagattga taatatagaa ttatatatta
    12061 aaagagtttt caaacttctt gaatttgagg gtattgaaca tatatattct aaaataaaaa
    12121 actatataac tataagtgct ggagtaagta taaaaaggtg tcatagtaga aaagatgttg
    12181 aaatattaat tgaagatgca gataagaacc tatataaatc aaaaaaagca ggtagaaatc
    12241 aatacattat aatttaaaat tgaggtgatt ttgttgcgaa aaaaaatagg aattatagcc
    12301 tctgatattg aattaaaaga aagaatagaa gaattatata gagaagatgt agaaaatgga
    12361 actataataa tcgacatact taacctagac ttaatggaaa atcaaggtcg tatacttgtt
    12421 gaaaaaggtg cccaagctat aattggtaga ggtggaggtt atagtttagt aatagataca
    12481 gtaaatgtac ctgttatacc aatgaatatg aagtcaactg accttttaag agcaatagaa
    12541 atagcaaaga aatattctaa aaaagtagta ttgattcttg gagacaatga agtttctttt
    12601 gactatgttg gctggagaaa tgtcataagt actgaaataa ctgaagaatg gtttgaatct
    12661 aagtatgaga taagaagtaa agttgtaaaa tatatagacc aaaaagatga agttgtaatc
    12721 gtaggaggag gtttggcatg ttcttttgca aggcaatatg gaattgatag tgtatttgca
    12781 actgctagtg atgaatctat aagagaagct gtagaatatt gtaaaaaatt attagataca
    12841 ttaggtgaag aaaagtttaa taatgaagtg ttacgaaata tacttgatgg tataaaagat
    12901 ggagtaattg ctatagatag taatggcagt ataattttgt acaatgaaag tgcaaaaaac
    12961 atgcttaaag tagagagaaa atgtgcactt aataaataca tcttagatgt atttcctaaa
    13021 atggagtgga tgttagattg tttacatgaa aaagaggacg tagaagatag aaagataaga
    13081 aatataaata atctaattgt taatactagg acaacattga taaaagttga taatagtact
    13141 tatggagttt taggaataat acaagatata accaagttac aaaacttaga aagaaaaata
    13201 agatttgact tgaatcaaaa aggtctctat gctagatata cttttgatga ttttttattt
    13261 aaagataaat taactaaaga atttattgaa gaagctaaaa aaattggaaa aagtgattat
    13321 acaactttac tttatggaga aagtgggtct ggtaaagaaa ttatagctca tagtatacac
    13381 aatataagta aaagaaaaga taggcctttt gttgccataa attgtgctac tatagcagaa
    13441 aatttacttg aaagtgaact ttttggctat gaagaaggtg catttactgg tgctagaaag
    13501 ggtggaaaaa gagggctatt tgaacttgct catggaggga ctcttttttt agatgaaata
    13561 aatagtctat cctttaatat tcagacaaaa ctattaagag taatagagga acgtcaaata
    13621 atgagaattg gttctgatta tataatacct ctggatataa ggattatagc agcaacgaat
    13681 gaatctttaa ccgaaaaaat agttatgggt acatttagag cagacttatt ttatagattg
    13741 agtagtttag agataaatat acctccttta agagacagaa gagaagatat aatacctttg
    13801 tttaacaatt ttgtaaatga agtattaaag gatgatggtc tcaatggaat aaacagtata
    13861 gatgaaaatt ttgttttgac taaagatgaa atggataagc tatataatta tagctggcct
    13921 ggaaatgtaa gagagttaaa gacaatagct caaaaatatg ttgtgacagg taaaattaaa
    13981 ttgagacaag atagagattt taaaactaaa aaattacttc ctaactctga agtagacaaa
    14041 tttaattctg aaacgacagc aagtgtagaa gtccaagatg aatctataaa tataagtaag
    14101 ataaatgatg gtaagataag tatagatata aaagaagtaa ataagtatgt tgaagaaaaa
    14161 ataataagta tgctttttgc tcagggactt tctaaaaatg aagttgcaca agttcttgga
    14221 ataagcagga catctttatg gaagaaatac aataaaaata tttaaatata attacatata
    14281 aattattttg aagtaatgtt aattttttaa aacaagtgtt aagaaaaatt aacattactt
    14341 ttttgcaaat ttttattttt ttagacaggc atatatattt ataagaaaaa tagttaaaac
    14401 acttaattta ataatgaaaa aaataataat tctaaacaaa atcaatttta cataaagtgg
    14461 gatttattgg catagtaatt gcttaatata taatgtaaga gtaaatacaa ttttaggggt
    14521 gatggtatga gtcaaagtat ggttggtaag catgcaatgt ggccaaaaga aaatgatgtt
    14581 atatttagca tatctggcag agctcaagca gcagagaagg cttttggtat ggataatgta
    14641 ataaatgcaa caataggcgc tctaatggat gattcaggaa aattgataac aatgaaaact
    14701 gtatatgaag aatataaagt attagataac tgtgagatag gtgcatatgc agctcttgaa
    14761 ggtcaaccag attacttaga agcagttaaa aaagtatttt tcagagatta cttaccagaa
    14821 ggacatataa gagtattagc ttcaccagga ggaagtggtg caataaaatt agctgtatgg
    14881 aactatacta atgaaggaga tgaggtatta acatctgatt ggttctggag tccatatgta
    14941 agtatagctg aagaggctaa tagaaaagta gttaattacc aactttttga tgaaaataga
    15001 aggtttaatt ttgagtcgtt taaagaaaaa tttgtaaata tagcagaaaa acaaggtaga
    15061 gtctttacaa ttataaacac accagcgcat aatccaactg gatatagtgt tgcagatgat
    15121 gagtgggata aaatattaga cttatcaaaa gaagtcgcaa aagataaaga caaaaagata
    15181 atatttttcg tagattcagc atatattgac tttgcaggtg atgatgatgt atgtagaaag
    15241 ttttttaaga aattttctaa tttgcctgaa aacgttctcg tattggttgg attcagtatg
    15301 tcaaaaggat ttacagctta tggtatgaga atgggagcta taatttgtat atcttcaagt
    15361 gaagatgtag ctgaagagtt ccattactca tgtgttcatt catgtagagc aaattggtca
    15421 aattgtaata gaagtgctat ggcagtatta tctaacattg taaatgaccc taaaaaattc
    15481 aaagaatatg aggatgaaaa agaaatatac aaaaacatgc ttactagaag agcagatgta
    15541 tttgtaaaag aagctgaaag agtaggatta gaaattcttc catatatagc aggtttcttt
    15601 gtaagtatac catgtgataa tccaaaagaa gtatgtgaag aattgactaa acataattta
    15661 tttgcagttc cattaaaaat gggcttaaga tttgcagttt gtgcagtttc tgaagataaa
    15721 tgtaagaaag caccaagtat tataaaagaa gcacttgaaa gtttagaagt aaaaataaat
    15781 aattaatttc attgaacaaa ttgggtggac tatgaattta ataattgtag atggagggaa
    15841 ttttatatga aacaattgat gacaggtaat gaagcaattg cacgtggagc ctatgaggct
    15901 ggtgttaaat atgcatctgc atatccaggg actccaagta cagaaatatt agaaaatata
    15961 gcaacatata aagatgcaat agttgcagag tgggctccaa acgaaaaggt agcacttgag
    16021 gctgctatag ggggttcaat tgcaggagca agaacaatgg cttctatgaa acatgttggt
    16081 ttgaatgttg cagctgatcc aatatttact tatgcatata caggggtaaa tggtggtatg
    16141 gtacttatta cagcagatga gccgggaatg cattcatctc aaaatgagca agacaatagg
    16201 atgtatgcaa aatttgcaaa gataccttta tttgaaccat caactagtca agaagctaaa
    16261 gatatgataa aagaagcttt tgaagttagt gaaaaatacg atacaccagt tttatataga
    16321 gttacaacaa gactttgtca ttcaaaagga ttagtggagt gctatgatag agaagaagtt
    16381 gaaattaaag agtatgttaa aaatgctaag aaaatggtaa ctgttccagc aaatgctcaa
    16441 ataagaaggg gcgttgttga agaaagaatg gaaattctta aaaaattctc aaatgaaact
    16501 gatttaaact actatgaaat aaatgataca aaaataggtg ttatagcatc tggtatgtgt
    16561 tgtaattttg ccaaagaagt ttttggaaaa aatgcatcat atatgaaact aggatttaca
    16621 aatccattac cttatgaaaa aataaaagaa tttgcagaaa aagttgataa aatatatgtt
    16681 atagaagaaa atgacccatt tatagaagaa caaataaaag catatggaat agattgtatt
    16741 ggaaaagatg taataccacc atatggagaa atgacaccag atgttttaag aaaagctata
    16801 tttggaaaaa caaatgatac tatagaatac aaatctgaat tagtaacacc aagaccacca
    16861 agtttctgtg caggatgtcc acatagagga ttcttctatg aacttggaaa gagaaaaaat
    16921 ttaatagttg gtggagatat aggttgttat actcttggat ttgctcctcc atataatgga
    16981 atagactatg ttgtttgtat gggttctgct tttggaactg cacatggagc tcaaaaagtt
    17041 cttaatatga aggatgataa tgaaaaaaga ttggtaggtg tacttggaga ctcaacattc
    17101 ttccatacag gaataaatgg acttttagat gttgtttaca atagaggtaa ttctatttcg
    17161 gttatattag ataatagaat aactggaatg acaggtcacc aagaaaaccc aggttcagga
    17221 tatactttac aaggtgctaa aactaaagaa gttgatatag aaggattagt taaagcttgt
    17281 ggaatagaac atgtaagagt tataaaccct aataatttaa aagaagtaaa tgaagcacta
    17341 gattgggctt tagctataga agatgaacca tcagtaataa taacaagatg gccatgtgta
    17401 cttaaaaaat tctctaaaga agatatagaa gaatttaata atccatttaa gactaagtgt
    17461 aaagttgacc atgataaatg tataggatgt aaattatgtt tgaaaactgg atgtccagct
    17521 ctatcatttg ataaagagaa taagttatca aatatagata gaaatcagtg tgtaggatgt
    17581 ggagtatgtg cacaagtttg tccaaaacaa gcaatagtta aggaggaaaa ataatatgac
    17641 taagagtata cttttggtag gtgtaggagg tcaaggaact atacttgcta gtaaattatt
    17701 aactatggga ttgatggaag ctggatatga tgtaaagatg agtgaaatac atggaatgag
    17761 tcaaagagga ggttcagttt cctcacaagt tagatatgga gattgtgttc attctccagt
    17821 tatagaaatt ggtggagcag atatattagt atcttttgaa aaaatggaag ctttaagatg
    17881 gttcaattat ttaaaaccag aaggaaaagc tttagtaaat aatcatagga tagattctat
    17941 gactgtttta atcggaggag ctgaatatca agaaagtgat atagatgcag agttaagtag
    18001 attaaatgca aaagttataa atgcagctga taaagctgaa gaactaggaa attcaaaaat
    18061 aatgaatgtt attttattag gatgtctagt taaatctatg caattagagt ctattgattg
    18121 ggaaaaaatt ataagtgaaa atgttaaacc aaaatttgtt gaattaaaca taaaagcttt
    18181 ccatgaaggt atggaaatgg ttagcaaata gtttataata gatataaata gactatagaa
    18241 attaaggtga aaggaagaaa attatgactt acagaatatt agccataaat ccaggttcta
    18301 cttctacaaa aatagcagta tatgatggag aagaacaaat tcttgtgaag acgatagacc
    18361 atccagctga agagattgca aaatataata ctatacaaga ccagtttgaa atgcgtaagg
    18421 aagcagtttt gaatattctt aaagaaaata gtatagactt aaaatctctt agtgcaatag
    18481 taggaagagg tggagtttta ccaccagtaa aatcaggagc atatttagta aatgaagaaa
    18541 tgattgatgt actaagacat agaccagtac ttgaacacgc ttccaattta ggtgctgttg
    18601 tggcacatgc aatatcagaa cctcttggaa tcaactcata tatttatgat tctgttgcag
    18661 tagatgagct tatagatgta gcgagaatat ctggactttg tggaatggat agatcaagtg
    18721 cagggcatgc attaaatact agagcaatgg ctttaaaata tgctaaggat aaaggaaaag
    18781 attataagag cttaaactta atagtagctc acattggtgg aggagtaagt atttatcttc
    18841 atgaaaaagg aagaatggtt gatatgctat ctgatgatga aggaccattt tctccagaaa
    18901 ggtcaggaag agtacctgct acaaaattag tggctgcctg ttattcaggt caatattcag
    18961 aaagagaaat gactaaaaag ataagaggta aaggtggtat agtttcatac ctaaatactg
    19021 tagatgctag agaagttgaa aaaatgatag cagaaggaaa tgaagaagca aaaattattt
    19081 atgaagcaat ggcttatcag ttagcaaaag gtattggaga gttagcaact gtagtagatg
    19141 gaaaggtaga tgctataatt ataacaggtg gaattgcata ttctgaaatg tttacttcaa
    19201 tggttaaaaa gaaagttgag tttatagcac cagtagaaat tatggcagga gaaaatgagt
    19261 tggaatcact tgcttttgga actttaagag tactaaatgg agaagaagaa gctagaattt
    19321 atagtgaaaa ttaataagaa aaactaaaaa tgtttatata ctaaaaaagt ggtatatccg
    19381 ttttttatac acgaaagctt agagtatagg tgaaaatgta taaaatttgg attgccactt
    19441 tttataatta aaattttatc ttaacctaat aaataattct gtaaaatttc gtatttatat
    19501 atatatttta ttggtattta ttgttattat tattatgagg agtgattttt gatgggaaaa
    19561 ataagtttaa aaagtatgat aagattattt tcaggttttt ttatatttgc aatttcttct
    19621 gtgcttatga ttaatgcaca tgtaggtctt atgccttggg atgtacttca ccaaggttta
    19681 tctataaagc taggcataac tataggtcag gcttctataa tggtaggagt tgtaattgtt
    19741 atattggatg cagtttttgg tgaaaatata ggatggggta ctttactcaa catgacattt
    19801 ataggaattt ttattgattt agtaatattt tctggagtga tacctcatgc aagcaacact
    19861 tatataggtg tgtttatggt tgttatagga attattttgg cagctatagc aagttttcta
    19921 tacttaggtg tttgtttagg aagtggaccg agagatgggc ttatgattgc tcttcagaaa
    19981 aaaactaata aatctgtacg tcttgttaga acaattcttg aaatactagc attagttgtt
    20041 gggtggttat taggaggttc tgtaggtatt ggtacgcttg taagtgcttt aggtttagga
    20101 tatgtattac aaatagtgtt tagaatattt aaatttgaca caaaattgtt gaaacataga
    20161 tttattatag atgatataag agaatggaag gaaaagaaaa gcaatgaaca taaatgtaaa
    20221 tcaagtattg taataaaaaa tgagcagaat taattatgct aaaatatatt tgtagtttat
    20281 ctaatttata gtaaagtcaa ggagattttg aaatggaatt atgggattta tataatgctg
    20341 atggaattaa aacaggaaat gttataaaaa gaggtaattc tattgaagaa ggttattacc
    20401 atttggcagt tgaagtgtgg attttaaata gtaactctca aattttaatt cagaaaaggt
    20461 ctaaaagtaa aaagacattg ccaaatatgt ggggaatgac aactggatgt attgtttctg
    20521 gggaagacag tttagaagga gcaattcgcg aagcaaagga agaaataggg atagatataa
    20581 ctaaagatga gatgaaagtt tttagaagta tgattcatga agatactctt tgggatgtat
    20641 acttagttaa aaaagaatat gatatatcca aagctatttt acaggaggaa gaagtaagtg
    20701 atataaagtg ggtaagcaca gatgaaataa gacaattact aaaagagggt ttgttttttg
    20761 aatatccaga gatatacgaa ttgctatatg agatagataa taataaatta aatatatgat
    20821 gtagagcaga tttcagtata agtaagatta tttaaaatgt atcttctcta aattttaata
    20881 ttgttttatg aaaattaata agttattttt agtatttttc tacttgtttt ttgagattaa
    20941 aataaaaagg gcagtcatta taaagtcata aaaatttggg gaggatttaa actatggaag
    21001 ataacaaagg attggcacgt gacagttcaa aatataaaat tgtttctata tctgtcgtag
    21061 taattattct aattacattt tggtatatgt taaatatggt gcttttaaca tttattatga
    21121 cttttatttt ctataacttg cttgtagcca caagaaaacg aattaagaag ttttcttctt
    21181 taaatattcc agattcattg ataattatag tgttatatgc actatttgct atattgttag
    21241 tattgattag ctatgcagtt gtaccaataa ttatagttca acttacagag ttgagtaggg
    21301 tttttagtga ttttgatgta aatcaatttg ctcaatcttt aggaccaaaa ttgtatccta
    21361 ttgtctcaaa gctggatttt aataaatata tttcacaagc agggctactt atagcatcaa
    21421 cagcaacaaa agttggaagt tttggagtaa atatattatt ggcattttta ctgagtttac
    21481 tccttttact tgaaaaaaat gaaattaaaa attttggaga taaactttct gatagtaaga
    21541 tttcttttat ttataattcg cttgtatttt ttggaaagag ctttgttaaa aattttggtg
    21601 aagtaatgaa agtacaagtt atgattgcct ttataaattc tgttgtttct atgattttct
    21661 taggtttcat gggattccct caaatatggg ctttaggatt tatgattttt gtgttgggtc
    21721 ttattccagt agcaggagtt atagtgtctt tgattccatt aactgtaata gcatttaata
    21781 caggaggaat aacaaaggtt tttggagttt tacttatgat ttgtatagtg catgcagtag
    21841 aaacatacat attaaaccct aagttgatgt cgaatagaac taaacttcca gtttgttttg
    21901 tttttattat tttacttgta ggagagcatt atttaggtgt atggggatta ctaattggag
    21961 ttccaatatt tatgttcctt atggatattc tgggtgttaa atttacttct aggtaatata
    22021 ttaaaataat aatttatttt tatatataaa ttatgaattg ttttaaaaaa gaacctataa
    22081 atagacatca ttaataaaga catctatttg ataggttcaa ttttgctttg tataaatact
    22141 ataaaactaa ataaaaagaa atttatttca tttcaaaagt ttcacaactt gcatttcttt
    22201 catttatatg aactttttca gctttgcaaa gttcattttt attgtattta cattttacag
    22261 cttcacaatg aatgttatct gtatcaactt ggttagtttc attagaacga ctagttatac
    22321 cagatgtata tttgtcttca aaagaagcac aataagtatt ttctgtagta gttgcttgca
    22381 ttccatctac ttttatacta ccagcataac aatatccact agtattataa gcacaattag
    22441 tagcagcaca atttaaatta ttatttttca taaataacct cctaagtttt atttaaactt
    22501 attatgtgaa gttatctaaa ttttatacac ttatttacaa ttacatttat cacatttaac
    22561 aactacatct ttggaagttt cccttcctaa atttttatta acatgataca catcaacatt
    22621 ttcagttgat ccacatatag aacatttaaa attgttttct agtagggttc tttctttaaa
    22681 taacttccaa tacatagaat tgatgtaatc attataattt accttgaggc atgtctcaag
    22741 aaagtttatg tatagattgt ctaaatctcc tgtatttaat tctgtatatt ctggttcaaa
    22801 atattcacaa catcctctaa aatcgggctt tgtatctgaa ataacacatc taatatcata
    22861 tctatagtct aggctaggcc ccttaaatga aagatgtgtg caaaaagaac aagatgtttc
    22921 tggtagattt ttttcaagtt catgtaattt attattcata agtattcctc caaaaaattt
    22981 attttaagta tataaacgaa tagattattt taaaactttt atttatttat attagagatt
    23041 taggataaat attccaataa ggagtaaata cttaagtatt tattactgta ttaaataaaa
    23101 aagaggcaaa tctaacttga gattgcctac ttttttatca ttttttaata aaatttattc
    23161 taagtattat tttatttaga tttagtcagc caacttagta tctgctttgc tttttaactt
    23221 tctaccagag cgtacagtta aaatagcata taatacagta aatatggcag ctaaaacata
    23281 tgatatattt atgtttaagt taaatccaat ttgagcatta aatatataac tgaatataac
    23341 aaaggaataa aacataccag gaattaagct tataatataa ttcttttctt ttattataag
    23401 gtaaactgta atcattgcaa atgcaaatat ggcaatagtt tgattactcc aagagaagta
    23461 tctccacaat atattaaatc cagaagcact aagctttgca aatataagga tggctatgac
    23521 aggaataaat atacagattg acaatataac acgatgtttt ttttcctttt ggtcataatg
    23581 aaagtaatct gcaagcatta atcttaaaga tcttaaagct gtatctccag aagttattgg
    23641 taaaacaatt acacctatta tagctatgat accaccaata gaaccaagta aatctcttgc
    23701 aaccaaacct attacatcag gagaacctac taattcctta ggtattcctt tattgtaaat
    23761 acccatagca gctgcagccc aaatcattgc aattaaacct tctaaaatca tcatattata
    23821 aaaagtagtt tttccttctt tttcatttga aactgatctt gctataagag tagcttgagt
    23881 tgagtggaat ccagaaacaa taccacaagc aactgtaaca aagaatgtag gaataagagg
    23941 aataccatca ggatgaatac ctttccaatt tgcaagactt aaattagcta aatcataacc
    24001 ttgtgtaaag attccaattc caacaccagc agcagataaa agtagaatag ctccaaatat
    24061 tggatatacc tttcctatga ttttatcaat tggaaatagt gttgcacaca agtaatatag
    24121 aaagataagt ccataaacta tccagacaac tggattattt atagtcgatt tcatatttaa
    24181 aatttgagta acaactaaat ccccaggtgt ataaataaaa actgcaccaa ctaaaagcat
    24241 taaaagacaa aggaatatat tatagacttg aaatacttta ttacctaaaa atctactgat
    24301 aagagaaggc atttgtgctc ctttttctct tatactaatc attccactca tatagtcatg
    24361 caaagctcct ccaaatacac agccaatagg tattagtatg aatgctattg gaccaaacaa
    24421 tataccttgg ataggtccta gaattggtcc tgtaccagct atattaagca actcaattag
    24481 actatttttc cattttttca ttgggacata gtctactcca tcactttgag caagtgcagg
    24541 tgtttttctg tcatctgggc caaatacttt ttcacaataa gcaccgtata aagcacctcc
    24601 tattagtaat atagccaagc cgattaagaa tgttgtcata atatcacccc atttataaaa
    24661 ttttttggtc tttgtataca tattatctaa atgtgtagat ttatattgaa tttaattctg
    24721 gacaacctac aaattctata aagtattaca actaatataa tttcagaaat aaatacatat
    24781 acataaccat gtacttagta tacaggtatt tggtaatatt ttcaatgtta tagcaataaa
    24841 gaatataaac aaaattctga taatatttta caaaaaaatt aaaaaatata aaaattagtt
    24901 taaatagatg gagaaaaaag gaaaatcaat tgagaatata aatgtctata tcttaacaat
    24961 attaagaggt ttaaaattct tgaagaaaga atagtcaagt gatataatga gtttacaggt
    25021 gtatatacac tagtacatat agaaagcggt gcaattatgg ataaagattt aacatatcaa
    25081 atcaaagagc taaagaaaga aaaaaatgca ataatacttg cccattttta tcaaccacca
    25141 gaaatacaag aattagcaga tgcagttggt gactcatatt atttaagtga gattgctaga
    25201 gattgtaaag aagaagtggt tgtattttgt ggagtaaggt ttatgggaga aagtgctaag
    25261 atattatcac ctgaaaaaac tgtattgatg ccagtaagta acgctgggtg tgctatggca
    25321 gatatggtag atgaagaagg cgtgataaaa ttaaaacaac agtatccaaa tgctttggtt
    25381 gtatgttata taaactctac agctaaagtt aaggcacatt gtgatgtttc tgttacatct
    25441 tctagtgcaa ttaaaatact agaaaacata gataataaag aaattatatt ccttccagat
    25501 aaaaatttag gaggatatat tgcagaacaa tttccagata aaaactttat attttgggac
    25561 ggatattgta aataccataa caatataaga gctgaagaaa taattgagtt aaaagataag
    25621 tataaaaatg cagaagtatt agtacatcca gaatgtaaaa aagaaataag agatttagga
    25681 gattatgtag gtagtacatc aggaataata aaatatgcta ctaatagtaa aaacaaagac
    25741 tttataatag caactgaaga aggtatatta catgaattaa agaaaaataa tcctaataaa
    25801 aacttttata ttcctggtgg aaaaatacta tgtacagata tgaaaaagac aacattagaa
    25861 aatttatata gtacacttaa aaatatggaa aatgaagtta ttgtagaaga tgaaatcatg
    25921 gaaaaggctt taaattcact gcttaacatg cacaaattag cagaaggata gagggataga
    25981 cttatgaatt tagaacaaga tgttttaata gttggaagtg gagtttcagg attatactgt
    26041 gcattaaatt tagataaaag tttaaatgtg ctagtagtat cgaaatcaac aattgaaaac
    26101 aacaatacat atcttgcaca aggtggaatt tcaactgcta gaaatattga tgatatagaa
    26161 tcctttgtag aagatacaat gaaggctggg cagtataaaa atagagttga agcagttcaa
    26221 gtacttgcag atgaatctat agaaaatgta gggcagatag tagaatatgg tatgccttta
    26281 gacaaagaaa atggagagat agattacaca agagaaggag cacatagtgt aaatcgaata
    26341 gttcatagta aggataatac tggagaagtt gtttttaaaa ctttattaaa agaagctaaa
    26401 actagagaaa atataactct tatagaagat gcctatcttt tagatatatt aaaagatggc
    26461 aataaatgta taggagctag aatttttaaa tctaaaaaag agattcatgt tttttcaaaa
    26521 atagtagttt tagctacagg tggaattggt gggcttttta aaaattctac taatcaaaga
    26581 catcttacag gtgatggaat tgcaatagct ttaagaaata atataaaaat agaaaattta
    26641 gaatatattc aaatacatcc tacagccttt tatgaagaaa ataatgaagg taggagaatg
    26701 cttatatctg aatcattaag aggagaggga gctaaacttt taaataaaaa taaagaaaga
    26761 tttgtggatg aacttcttcc tagagatgta gtttcaaaag ctatttttga gcaaatggaa
    26821 aaagataaat taccttatgt gtatttagat gcaacacatt tagatagtga atatttaatt
    26881 aatagatttt cttttattta taatgaatgt ttagctagag gaacagacat aacgaaagaa
    26941 tgtataaagg tatctcctgc acaacattat tttatgggcg ggatacatgt agatttggat
    27001 tcaaaaacat ctatggaaaa tttatatgca gttggtgaaa ttagttgtac aggtgttcat
    27061 ggagccaata gattggcaag taattcatta cttgaagggc ttgtattttc aaaaagagca
    27121 gctaaaaata taaactcagt tatagataat gtaaaagtta agtttataga tgtaccagat
    27181 atggatatag atatagaaca ggtaaaaaaa gaaaataaaa tattagtcat aaaagaaatt
    27241 gaaagaacaa gtgaggattt tggcgatgaa ttatttgatt attgatagaa tgatacagga
    27301 tgctttgata gaagatgttc caagtgaaga tataacaact aattctattg tggatgaaaa
    27361 ttctaaatct actgtagatt taatttgtaa acaagatggt ataatagctg gcttaggtgt
    27421 atttaagaga gtttttgaga tacttggtga tgtagatgta aaattatata aaaatgatgg
    27481 tgatagagta aagaatcgtg aaaagatagc tgtattaaca ggtagtacta gaaacttact
    27541 tgtaggagag cgtgtagcat tgaattattt acagagaatg agtggtatag ctactattac
    27601 aagtaggtat gttgaaaagc ttgaaggtac aaatacaaaa ttattagata gtagaaaaac
    27661 gatacctaat cttagaatat tagataagta ttctgttaaa gtaggtggag gatgcaatca
    27721 tagatttaat ttatctgatg gaatattgct taaagacaac catattgggg ctgctggtag
    27781 tgttaagaag gcagttgaat tagctagaaa aaatacttct tttgttagaa agatagaagt
    27841 ggaagtggaa actttagaca tggtaaaaga agcaatagaa gctaatgcag atataataat
    27901 gttggataat atgagtttgg aaatggcaaa acaagcagta gatattataa atggaagagc
    27961 cattgtagaa ttttccggaa atgtaaattt agatactata gaagatatag gaaaaattgg
    28021 tgtggatgtt gtttctgtag gagcgcttac acattctgtt aaagctctcg atataagtat
    28081 gaagaatttg agaaatatat aaattttata ttgaaataaa cttaattaaa atagactcct
    28141 taaatttgtt ttataaattt aaggagtcta ttttttattc attaaaatta ataaaaatag
    28201 aaaaaaatca atcaataatt taataaaaat agataaatac tatatacact tttaataata
    28261 tagttaatat ctattttaca gataaataag aataaactta taatataatt gtatctgtaa
    28321 aattttgtaa aatataaaaa gtataggggg aataaaaatg aaagtagctt atatttttag
    28381 tagtactaat acacataaaa ttctagacaa aatgataata ccacaacttg aacaaggaac
    28441 tcatggagta gacgttctag ggatgttttt ctttatggat aataccttat ttttatctaa
    28501 aggtaatcct gtaggcgaga gactaagtaa attacatgaa aaaactgata tgataataat
    28561 ggcttgtgac caatgtgcta tagaaagagg tatagagaat aatttggttg atggagctac
    28621 aattggatgt ttcccaaacc tatatgcttg tttaggcagt gcaggtgtgg accaagttat
    28681 aacgttataa attagtatag gatacaatcc atagaaaaat ttattttctg tggattattt
    28741 taagtaaaag ataaattgtt taaagtaggg gattaacaaa tgtctaaaat tttagttgaa
    28801 tttataaaca cttgaccatc ttgtgatgaa catggagtgt ttataaaaaa aatgtcagaa
    28861 aaatatgctg ataaattgga aataaaatta tatcaagcag ggaaagattt ttcgtatata
    28921 aaaaaatatg ggattataac aaaaggaact ttaataataa atcagaaaaa gaaatatgat
    28981 agattaaata aagatacaat tgaaagggca atagtagaag ctataaacaa taattaaaag
    29041 tttaaaaatt aggagtatca aaaatgaata tattagaaat tgttttaaat ggagttaaag
    29101 atactatagt agcttctata gttacactga atggagcatc aggatggctt atgataagtt
    29161 ttatattggc aggtgtactt cacaatgttt taactccaag aaggtttcaa aaacaacttg
    29221 gaaataagaa attttcttct ttaattaaaa gtactatctc aggaatgttt ttaccaatat
    29281 gtagttgtgg agtaatacca cttggaataa gtatgtatta ttcaggagca tatttaggac
    29341 cagtacttgc ttttatgaca tcaactccaa taataaatcc aatagctgta gttctttgtc
    29401 taggtctttt aggtcctaaa gttacaatca tttatctaat agctggtttt ttagtaccat
    29461 ttttagtagg atttttagga aattgttttg gaaaagaaga attatcactt cataatgatt
    29521 cagaggaaga agtaatagaa ttagaagaag aaaaaagaag ttttatggga aatatgattg
    29581 atggtcttaa atggtctttt ggtgaattag cccttactat tagtaaatat gtagtaatgg
    29641 gtatggtttt tgcaggattt ataacaacta tttttccaaa tagtataatt caaaaatatt
    29701 taggaaatcc aggtttgcta tctcttggaa gtatagcaat acttgcatgt gttatgtatg
    29761 tatgtgctgt aggacatata ccgtttatag cagcccttgt tgcaagtgga gcatctcctg
    29821 gtatagcgat aacatttcta atagctggag cagctacaaa tctaccagaa cttataagta
    29881 tgtttaaact tattggaaaa agaactgtta ttatatattc tgtaactttg acactgtctt
    29941 caataataat tggatatata acaaatttac ttttagtgaa taataactca gtaaatttag
    30001 atgcaacaaa ttcttcaata cagttggcaa ataaactaat gttaaatata cctgatagtt
    30061 ttgagtatgt atgtactatt ttaattattt tatttgcatt taaatcaata ataccaaaga
    30121 tgaaagaggt cataggaaat catgcttaaa aagatagtta taatatcctg tatagtagtt
    30181 gtgttaatca ttttatcaaa aatagttgat gataacatca aagaagatgc ttctattcca
    30241 aatgtgaata aagaaacatt agaatatttt agaaaaaatt ataaagaaga cataataact
    30301 tgtgctgaag aagacttaaa taatgatgga aaaaaagatt tagtagttat atataaaaaa
    30361 agcaataatt caaatgaaat ggtagtcgta gtttctgata aaaatagcca ctatataaca
    30421 aagccaatac cagcacctat agagaatcaa acgataacct ttaaaaatat tgatgataaa
    30481 gcaccaatag aagtaattgt atcagggtct aaaaatggta atgtaggata tgctatttac
    30541 agagtagagg gtaaaaaatt tgttgattta tttggcgaag atatggacaa atgttgctaa
    30601 aaataataca taaaggtggg aaatttatat gaaattatct aagaagattc aagcattaat
    30661 cttatttggt gtaatgggta catctatatt aacaggatgt agtagtaaac caaaagaaaa
    30721 agaagaagca aaaactggaa aagatgatta tacaataaca gtaggttatt ataattgtga
    30781 ccatatgact gcgggaccag tagcagaatc ggcaggaata tataaagatt taggtcttaa
    30841 tgtaaaaact gttggaaatg gtaaagttcc tgaagctatg gcagcaggaa aaatggatgc
    30901 aggttacata ggaactaagg ggttagttgg agcaatacct aagggttcgc caataacaat
    30961 agcagctaac aaccatactg gtggttctga atatttaata gtttcaaaag atataaaaga
    31021 acctaaagat ttaataggta aaaaaattgc aacagatatg agtgatttct tatggacaag
    31081 tgattatggt ccagaaacag gtctaccaac tgacccatca aaatatgaag ttgtaaatat
    31141 ggattcagac aaagataaat atttagctct taaaactggg aaaattcaag cttttacatc
    31201 ttgtgaccct tggggttctg tagctgaaaa tgacggtgca ggaaaaataa tagcatctac
    31261 tcaatataaa gaaaaagcta atggcaaaga atataactgt tgttcattct cattaaacaa
    31321 aaactttata aaagaacatc cagatttagc aaaaaaattg gttctagcac atacaaaagc
    31381 aatagaatat atatatacaa atccagctga agcagctaaa atatttgcaa aatattataa
    31441 tgtagaagaa gaagttgcac ttagaactat ctataagaag actgttggag aaggtagaac
    31501 tcttacttgg aaagttacag gtgaagaata taaaaataat ttacaaatgt ataaagattt
    31561 aaaggcttta gatgatatac ctaaatatga agatacgatt gatacaagct tattggactc
    31621 ttgtggagct gatgattttg acaaatttat aaaagaaaaa gttaacccag agtttcctga
    31681 aggtatgagt tatgaagact ggaaagcaaa ggtattataa ataaatggag aatatgaaaa
    31741 atataataat actttttatc attattttgg gaagtatatt tataatattt tttaattttg
    31801 aagataaaga agaaataaaa ggaaaattaa gaataggggt atctgatgat acctctggtt
    31861 ttgtaataaa ttatatggta aatagagact actttgaaaa tataaaagta agtgatataa
    31921 tggatatttt tacaattaat gattgctgag caagtacaat gcagtgggct ctgagttcag
    31981 aggaaataga tatagcaatc atatgtaaag atgctgcaaa acaatatgta aatgtaaata
    32041 gtggatttga aattgttggt actgtagttc aaaattctga tatatttcta ttaagtgata
    32101 ataatcctga aaagatagga gtcattcaaa atagagatta ccagtcagaa ttggttaaaa
    32161 aatactacaa gaatgtggaa gtagctccct tattagggac tgcactagca tatggattag
    32221 aaagtaattt agtagatggt gttgtaatag attgcataaa gtcaattggg ttagagggta
    32281 aaagaaaatc tacaactaaa ttaggagatt atgataccta tgtattagtt gtaaataaag
    32341 agtttaaaaa aagtaaagca tatagtgatt ttataacact ttacaataaa agcgttgatg
    32401 ctttaaagaa taaagctaca tttaagaaag tattaaaaga gtacaggaat ataagaaata
    32461 tagatatgga ggaaataagc aattggaaat taaaatttct aaagataaaa gcgatagatt
    32521 aactaagaaa aaaactgatg gtagtatgga tattttatat aaaataatac tattagttat
    32581 tatattttta gtctggcatt ttgcagcaaa agatataggg agttctttgt tacttccaat
    32641 gccagtagat gtaataaaag gtttcttttt ctgtgtgaca gatgcagaga cagtcactaa
    32701 tctttttata acattgcaga gagtacttaa aggttttatg tatgcattat tgtttgggct
    32761 tccaatagga tttattatgg gattttctaa aacttttgaa agggttttat ctccagtagt
    32821 agattctgta aggcaagttc caataatggc atgggttcct cttactatag tatggtttgg
    32881 tataggagat ggtccaacaa tatttttaat agctttttca ggggttttcc ctataatttt
    32941 aaatactatt caaggagtaa gagcaatatc aaaggattat tataatgcag ctagaagtat
    33001 gggagcatcg ccaattgtga tatttacaaa tgtaattgtt cccgcatctc ttccagatat
    33061 actaactggt tcaaggattg ctataagtac aggatggatg tctgttatct gagccgagtt
    33121 tatagctacg agtgccggtc tcggttactc aatggtacaa gctcaaacat taatgcatac
    33181 agatgtatta attgggctta tgatatttgc agctttaata ggatttataa tagatagggt
    33241 attaaagttt ataaataaaa tcctttgtag atggaggttt gcagattaat gaagttaagt
    33301 gtaagggata taaataagac atttgtaaat aatagagtac atacaaaggt tttagaagat
    33361 ataagtatgg atatagatga tggacaattt gtctgtcttt taggaccatc aggttgtgga
    33421 aaaacaactt tacttactat aataggtggg tttcaaaaat cagaacgtgg agatgttttt
    33481 ataaatgata aaagagttaa aaaaccgggc atagatagag cttttatatt tcaaaattat
    33541 gctttatttc cttggaaaac tataagaggt aatgttctat ttcctatgaa acagcagaaa
    33601 ataccaaaag aaaaaagaga agaaatgcta gaagaacttt tggttatgtc agacttgaaa
    33661 ggaaaagaaa aactgtttcc gcatcaatta tctggaggaa tgaaacaaag agtggccatg
    33721 ataagagctt tagcatgtaa tccagaggta ttactaatgg atgaaccatt aggagctgta
    33781 gattttcaaa tgagacaaaa tttacaggaa gagctagaac gaatatggat aaagaagaaa
    33841 ataactgcat taatggtaac tcatgatgtt gatgaagctg tatatatgag tgatagagtt
    33901 atagtaatgt cgagagataa aggaagaatt attgatgata taaatataga tattccaaga
    33961 cctagaatta gaggaagcca aaaatatgaa gagtacaaaa acaaattaac tgatacttta
    34021 tcaaagtgtt atgaagttta aagaggagta gacatgagtc aaatagaaaa atacaatagt
    34081 ttgaataata cacaacagaa aataagaatc tctattatgg atatgataat agataaaggt
    34141 tctagtgtta cacttcaaga agtgactgaa tatgtaagta aaaagttgaa tatagaaaaa
    34201 gaatatatag aaaggacact acaatatttt atttataaaa atataatggt tgttgatggg
    34261 aatagtataa attttatata tcctgtatca gcattgccaa caaatcataa agtaactttg
    34321 agagataata gaagtttcag tgcaatgtgt gctatagatg ctataggaac ctcttgcaca
    34381 ttcaaccaag atataaaaat aaactctatt tgtagtgcta caggtaagga aatagaagta
    34441 attataaaaa atgaaaagat tgagtatgtg aataatccaa acttaagagt gcttcatata
    34501 aatcttgata agcatctaaa ttgggctgct agttgctgaa atataatgaa tttcttctgg
    34561 acgaagagtg attttgatgc ttggacaaac gaagcgggat tatctgatga tgaagatata
    34621 tattgtttag atattaatga ggcaatagta gaatcatata aaatatttaa actcaaacaa
    34681 aaggtactat catagatata catatatgaa aaactaaaaa tgacctttag ataaaaatga
    34741 taggtaatat ccatactata taaattagta tagagtaggg atgtgaaaag tatttaaatc
    34801 taaaggtata tttttagttt tttttagatg attagatagc cttattaagt atatatttat
    34861 ttataacctt tgcaactcca ttttcattat tagtatcagt aacataatct gcaatttcct
    34921 ttatactatt acgtgcattc cccatagcca caccaagacc tgcatacttt atcatatgtt
    34981 ggtcattttc ttcatcgcca acagcaatag cattttctat aggtatattt agattcatac
    35041 ataatgtttt aagagcagtt cctttattag tagttttacc taaaaattct agataaaaag
    35101 gagcagacct tactatagta tatttattga ataaattttt aggtagttgc tgtatgattt
    35161 cttccaatct ttctggttca tcaactatca taattttaca gattttaata gattcatcaa
    35221 ttttatcttt ttgtatatat ttgacttcta tattatttaa tttcgcttca tgaagtgtat
    35281 atttgccagg cgtttcattt ggtgtaatta aatttgtcat tgtatttatg tgtattttag
    35341 tcttatattt tttacaaacg ttattatata taaaatcaaa atcatctaaa ctcatttcta
    35401 catcatgtat gattttctca cttttaactt cttgaataat tgctccatta aagcatataa
    35461 cataatcacc ttcatctgtt aaatttagtt gatttagaag ttcttttaca ccaggaagag
    35521 gtctgcctgt tgttataact acttttgccc cagccctttt tgcctcctga atggactcaa
    35581 agacttcagg agtaatcctt ttttgtgtat ttaatattgt tccatcaatg tctagtgcga
    35641 ttaatttgta catatcaacc tccaataaat tatatactca aatttcctgt gaaaacgttg
    35701 acacagctag tgttgaacaa agtttcagtg ggaaatatgg tttgttttgt atactattat
    35761 atcaagagat aagtaattta taaagtttaa taatattaat tttttgataa aaatattact
    35821 tatgtgagat gagaatgtaa aaactttgta atcaataatt ccaaaattct taattacaaa
    35881 taatggtatc gtttgcattg ttaatataaa taaatgtata ttatatagtt agaagtttga
    35941 ataaatagac tgatggtaat ttgttatatt agttagtttt gtgttataaa atattgtaat
    36001 tccattaatc atatgttatt attcaacatg attataatat aaagaatatt tgatatatat
    36061 aataatttat aaaagagtat tacatagtac atgtaaatct atatttataa atacaataaa
    36121 gtaaagttgt aaaggagtgc tttaaatgaa gttttcagag tttaagtatg aaagacccaa
    36181 ttataatagt atgaaaaaag agtttttgag ttgtgtagaa gatataaata attctcgtaa
    36241 ttataaagag caacaaaaaa atatacataa gattaattta ttaagaaata aaatagaaac
    36301 gttgtcaaat atagcttcga taagatatag tacagacaca tttaataaat tctacaaaga
    36361 agaaaaaaat tattgggatg aatatatgcc tttgtatgaa gaattaaatt catattttta
    36421 taatgccatt gtaaattcaa aatttaaata tgatttgata aaagagtttg gagagcaatt
    36481 tttcacaata gtagagtatt ctttaaaaag tttttccaaa gaaataataa gtgaattgca
    36541 ggaagaaaat aaattgtgtt cagagtatac tagactttta gcttcagctg agataatgtt
    36601 tgatgggaaa ataagaaatt tatctggtat ggggaaattc atgtattcta agaatagaaa
    36661 aacaagagaa ttagcaaaca aagcatatta taatttcttt gaagaaaatg aaactaaatt
    36721 tgatgacata tttgataaat tggttaaact tagagataag atgtctaaaa aattaggttt
    36781 tgaagatttt gtagagcttg ggtatgttag aatgatgaga agtgactaca gagaatatat
    36841 gataaaaaat gttagaaaac aagtactaaa atatgttgtt ccaatggcaa atgagcttta
    36901 tgaaaaacaa gctaaaagaa ttggtctaga atatttaagt tacatagatg aaggcgtgga
    36961 atttttaaca ggaaatgcaa gtttaaaggg agattcaaga tacataattc aaaatggtaa
    37021 aaggatgtat tctgaactgt caaaagaaac aaatgaattt tttgatttta tgttagaaaa
    37081 tgaacttatg gatttagaaa cgaagaaagg aaaaggagct ggagggtatt gtacttatat
    37141 accagattat aaatcaccat tcattttttc taattttaat caaactgctg atgatataga
    37201 tgtgttaaca catgaggcag gacatgcatt tcagttgtat atgtctagat ggattgatat
    37261 gccagaaatt aattttccaa cgcttgatag ttgtgaaatc cattcaatga gtatggaatt
    37321 tataacatgg ccgtggatgg atttattttt taaagaagat acagataagt acaaattcac
    37381 tcacttatca tcttcaatta aatttatacc ttatggagta attgttgatg aatttcaaca
    37441 ctatatttac aaaaatccta atgtagataa gtcaaaacga aaagaaatct ggagattttt
    37501 agagaaaata tacttacctc atagaaaata tggtgataat tcttttttag agagaggttg
    37561 ttggtggttt aaacaaggac atatatttaa aaatccgttt tattatatag attatgtatt
    37621 agctcaaatt tgtgcgttac aattttggaa aaaaatgatt caagatagag atgcaggatg
    37681 gaaagattat ataaatatct gtaaagttgg aggaacaaaa tcatttttag atattgtgag
    37741 tatgggaaat ttgtattctc catttgatga tggctgtatt gagtctatta taggtgatgt
    37801 taaatcttgg tttgatgaaa taaatgacag caaattataa aaaattatga gaattttatt
    37861 gtataaaagt gaaaaattaa aaaatatata aaaagtgatt atttgttgtg aaaatagtct
    37921 tgtttttaac taaattgata aaataaacta aaaaagattt gtacttaaaa aaaaaagaaa
    37981 atacaagaaa tatgcaatat caacatttgg aaaaaaaagt aaaaatgtat acaaaataca
    38041 tataaaaaaa ctattgcaaa ttttatagaa tgtttatata cttaagtcaa cagagataga
    38101 aaaaagctat ttatagaaaa caaaggataa attgcttaat tttaaatttt ctgaaaaaaa
    38161 taataatccg gatgaagagt atgggagact gctttataaa aagcgaccga agggacaagt
    38221 ttaatcttac ttacccaaaa gattagatga aattctcagg taaaggtgac tgtacttgga
    38281 cggggctctg aaaatgattt taacagggaa gacaaattgg gagatttgtt tttcctgttt
    38341 tttatttatc aagtaataaa taaaagtttg aaagagagta aaaaaatgat aataattacg
    38401 aataatccaa aagtaaaaga agaagttcaa ggcagagaag ttttgtttaa agacacaact
    38461 tatattggaa tcttagaagc aagtagagat ttgatacatg aaggttatga acttttatct
    38521 catccactct atgggagtgt aaagccaaat gaaacacctt acaggactgt tatactaaag
    38581 aaaggaaatc gtttggatat aaactcttta accttaattg aagaagcaat catcactgca
    38641 agtaaatttc agaataataa aaagactcca aaatggacag aaagtgttca agatgatttt
    38701 agagtaattg attatgatat attttataat acaatacaaa gaatgcagta tgaataaaaa
    38761 aattgttaaa aagttattaa aacagcctaa atattaaatc taatttaata ttaaataaaa
    38821 tgagaaattt aattggggag gataagtcaa aatggaaaat gtgtatgact tagtaataat
    38881 tggttcagga ccagcagggc ttgcagcagg tctttatgga gcaagagcaa agttaaaaac
    38941 tctaatccta gaaaaagaca agactggtgg acaaattgta ataacacatg aaattgcaaa
    39001 ttatccaggg tcagttccaa atgcaacagg accaagttta atagctagaa tggttgaaca
    39061 gtgtaaagag tttggagcag aaatgctaag agacaacatt gttgatactg agctagatgg
    39121 agatataaaa gttttaaaag gggaaaaggc agaatataga gcaaaagcag taataatagg
    39181 aacaggagca acaccaagaa agattggttg tcctggagaa aaagaactta ctggtaaagg
    39241 ggtttcatat tgtgcaactt gtgatgcaga tttctttgaa gattttgaag tatttgttgt
    39301 aggtggagga gacagtgcat tagaagaagc aatgtattta actaaatttg ctagaaaagt
    39361 aacaattgta catagaagac aaggatttag atgtgctaag agtgttgaag aaaaagcaaa
    39421 agctaatcca aagatagagt ttttattaga tacagtaatt gaagaaatca aaggtgatgg
    39481 aatattagaa tcagttgtat ttaaaaataa agttactgga gaaactcatg aatactttgc
    39541 agatgaagaa gatggaacaa tgggagtatt tgtgttcgtt ggattagatg ctcaaactga
    39601 tttattcaaa ggtaaagttg atatggatga aaaaggttac ataataactg atgaagatat
    39661 gagaactaac ataccaggcg tatttgcagc aggagattgt agatctaaga ctctaagaca
    39721 ggttgtaact gcaactaatg atggagcaat tgcatctata gtagctgaga aatacattga
    39781 tgaaaaattt gggaactaga atctgtaaat taagaaatag tgtctgtaaa tttaatgaat
    39841 aatatttaaa attaaaataa aaatttcaag ggggaataag aaaatgttag atttagataa
    39901 ggctacattt gaagaagaag ttttaaatgc agaaggtttt gtatttgttg atttttggag
    39961 tgaaggttgt gagccttgta aagctttaat gccagatgtt cataaattag ctgagactta
    40021 tggggataaa ataaaattct gtaagatgga tacaacaaaa gctagaagat tagctataaa
    40081 acaaaaagta ttaggtcttc caactatggc tatatacaaa gatggagaaa aagtagacga
    40141 agttactaag gatgatgcta cagttcctaa tatagaaaac atgattaaaa aatatcttta
    40201 atatgttgat aaattattaa cat
//
LOCUS       DAMJXI010000034        38537 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.036, whole genome shotgun sequence.
ACCESSION   DAMJXI010000034 DAMJXI010000000
VERSION     DAMJXI010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38537
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.036"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(68..679)
                     /locus_tag="PC465_002208"
     CDS             complement(68..679)
                     /locus_tag="PC465_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2649501.1"
                     /translation="MKMVKKLILSTIMALVLVLTIGCSNAEEKVKSNFEANLAALEMY
                     KYDEKGISDALTEAEYKQIQTYNSKDKVSMIAQLTPLYGKENAEKIYETIVKLIQGVE
                     KTVTVESSSKDKITLKVVSKALDTSKVMSEANTLVKSYVTDEKNYDKKEKEVQDDMTK
                     MIIDLYNKKPTKEVTTMITYTKKDGKWQPPSNIQKLCEGIYTI"
     gene            complement(771..1760)
                     /locus_tag="PC465_002209"
     CDS             complement(771..1760)
                     /locus_tag="PC465_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HDF2649502.1"
                     /translation="MLLLKKDDIKKVFTMRDAIEADKEAFRIYCEGKSVNPLRTNISV
                     PSQDASMLFMPGYVEELGCGGIKIVSVFPKNAQKGKPVIPATVLLLDGETGEVSAVLD
                     GTYVTQIRTGAASGAAIDVLAKKDSKIGALIGLGGQGEPQLEAMIEARNLDEVRVFSR
                     NKESREKFAEEMNLKLSKYNTKIVAVESSDEAIDNADVIVLATPSKQPVLNGNLVKKG
                     ALISAVGSYMPDMQELCPNCLTRASKIFFESTDAVLSESGDILIPLKEGKISKDDFSG
                     DLGNVINGTIPGREDDDEIIVFKTVGIGVQDVVTAKRIYDKAKENGIGIDWKW"
     gene            complement(1827..2690)
                     /locus_tag="PC465_002210"
     CDS             complement(1827..2690)
                     /locus_tag="PC465_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HDF2649503.1"
                     /translation="MKFFKVDTKAKVLRYVFVLTLTIMAVLAIKHDYKYNNLRKDASI
                     NLNSNKEAVTVMSNQSLPKGNTNSKQTLSVSTIGSKTIVKNDEYLESTINMPVITNSN
                     KIVERSTNDKIKNDIFEFYNKSYKEAKQYLKDNPDEKNKFVANVDFELKKNTDSALSI
                     KVRYYTYSGGAHGFYQDIAYNVDMRTGKFLELMDLFKDNTKYKEVIDEEIKRQIAELE
                     KKDEENIGIYNFKGIKENQNFYLQDENLVVYFDLYDITPYAAGIPEFSINKALISSML
                     KPEYVDLFDLK"
     gene            complement(2796..3392)
                     /locus_tag="PC465_002211"
     CDS             complement(2796..3392)
                     /locus_tag="PC465_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheB"
                     /protein_id="HDF2649504.1"
                     /translation="MERFNNMVIAIGASVGGTEAILEIIKDLPKSTPGIVVVQHMPAM
                     FTYMYAQRLDKQCIMNVREAKNNDRVEQGNVLIAPGGYQMKLCTDKQGYYVTCEKGER
                     ISGHCPSVDVLFDSVAEVAGKNSIGIILTGMGYDGASGLLKMKENGSFTIGQDENSCI
                     VYGMPMVAFDRGSVMLQLPLGEISNCLIRHINILKQKD"
     gene            complement(3432..4235)
                     /locus_tag="PC465_002212"
     CDS             complement(3432..4235)
                     /locus_tag="PC465_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HDF2649505.1"
                     /translation="MIKLTDEEFIVLVNHVKKEYGIDLSKKRALIEGRLYNTMIEKKL
                     SSFSQYMNLLFKDKTGNEAINLINRLSTNHTFFMREPQHFEFIQNSILPFWEENNKIR
                     NINIWSAGCSSGEEAYSIAMTLDDYFGYNKELWNIKIIATDISTNSLEKAKRGIYIES
                     NVNNVPELWKKKYFIDNKDGTFKICDKIRKSVIFKPFNLMNDFSYQHFDLIFCRNVMI
                     YFDLKTREELINKFYNATKKDSFLFVGHAEVINRSSTKYKYVKPAIYKR"
     gene            complement(4271..4711)
                     /locus_tag="PC465_002213"
     CDS             complement(4271..4711)
                     /locus_tag="PC465_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HDF2649506.1"
                     /translation="MAKDEIIKQVLTFYVNDVIYGIELENVIETIRFQSITYVPCLPT
                     YISGVINLRGRIIPVINMHIKYNLPKADYNERTCIIITKVDEYQVGIIVDKVVDVIHI
                     ENLNLLETTNSNNTNINKDIKEIAKVEDNSILILDIRKFLINSI"
     gene            complement(4724..6826)
                     /locus_tag="PC465_002214"
     CDS             complement(4724..6826)
                     /locus_tag="PC465_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HDF2649507.1"
                     /translation="MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIM
                     HTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEVLDNDLLFDLVFQSLDFIRRDID
                     ELQSRGCISSDYSNFIEGIEEYVSTLELSSSMKSKDNANLESKDEKEVIDSNFEYKED
                     SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQ
                     FVAKEDKAIVYKTIEDNLYVKEYINISKKEIEMKNTSNNDAVENKLKDNNKVSKSYQN
                     NYTEDEIQEDVLNEKTDMEKDSLSEDNEHLPISKQSIMSVNLEKLDLLQNIVGEIVIM
                     ESMVVNSVNSTGVDIDNFNKATRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDM
                     NKKLDKNVELITIGAETEVDKSVIDNLAEPFMHLIRNAMDHAIEPIEERIAKGKEEVG
                     KIVLSAENLGGEAVISISDDGRGIMRDKILAKAKEQGLLKHQSNEYTDDEVNSLIMTP
                     GFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKQDEGTTFTIKIPLTLSIVEGM
                     KFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNKTELITIYGACIPIIRLHKIYNIQT
                     KVTNLMNGNMIIIENEHKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTIL
                     GDGSISLIIDADSIIEIY"
     gene            complement(7039..8742)
                     /locus_tag="PC465_002215"
     CDS             complement(7039..8742)
                     /locus_tag="PC465_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HDF2649508.1"
                     /translation="MKREVKLSKLAIVLLIIIVLAVLAGIFSSISSYKAFEKVEKSIN
                     DMNNLRTQSQYIKDTTREISDVLRRYVFTGEKKNKDIYEKELYGKTRESALNKLEKIG
                     LTKSESNKILEAKEISDSLVPTEQSAIKAVESNDKSKAQSIIFGSDYINSQEKMDSLI
                     NEFQEDIVTRSNSKIVEVKKELQSLILRTIFILSLLIILTIIEYTVIKLKIVIPINKV
                     EKHFSRIASGDLRTSIDVEESKSEIGLLVSSVKKMQSMLLNYIDLIDSTLTSIAKGDL
                     RVEIDQEFIGDFKSIKISLESIINSFNGDFSEINLSAEQVASASEQVAAGAQALSQGA
                     TEQASSVEELASTINEISDGIKKCADSASLACEVSDQSASQVGFGSRCMDDMMTSMGE
                     ISEKSSEISKIIKTIDEIAFQTNILALNAAVEAARAGQYGRGFAVVADEVRSLAGKSA
                     KAAQNTAILIEEAIKTVENGVRIAKETANALDLVVNGVEKTTNYINGISSAVHSQEVA
                     ITQILSGIEQISIVVQMNSATAEESAAASEEMSAQAQILKELVEKFHLKESEVRESSW
                     V"
     gene            complement(8768..9727)
                     /locus_tag="PC465_002216"
     CDS             complement(8768..9727)
                     /locus_tag="PC465_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2649509.1"
                     /translation="MKNKQQGTILVVDDSVLMCDLIDKTLTKDNFKVKKAFNAIEAKE
                     FIEEFIPDIILLDIILPDNSGFEFCKEVKSNARTADIPIIFITSKNTDTDIVKGFGVG
                     AIDYMVKPFSMTELKARVIAHLEVKKSQDKLKKINNELESSLEKLNRLVVRDYLTGLY
                     NRRHIINQLMEQRRINKYSETSISLILGDIDDFKVINDTYGHEAGDFVLTVISSIIKK
                     NCRQIDTVSRWGGEEFLIMLTNTPIEGAKILSERIRKEIKEFDFNYKEHKIKCTITLG
                     VVEVNSNISLEENISLADKAMYEGKNLGKDCSVVSTMKGLKKI"
     gene            complement(9863..10381)
                     /locus_tag="PC465_002217"
     CDS             complement(9863..10381)
                     /locus_tag="PC465_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-binding chemotaxis protein CheW"
                     /protein_id="HDF2649510.1"
                     /translation="MRFPDDPYLDYGLIDEGIKYLKFKVDEQDFGVELEKVIEITGNQ
                     EIIFIPELPTYSKGIINLRGKIIPIIDMSLRLKKDELMTTNCMYIVVTEIKDLVVGFV
                     VDRVDDIVSLEKSKISPPPRVTIEYSDYFVSGVGELEGKIITLLDLEKLLTDKDEVLI
                     DELINGFDCTIM"
     gene            complement(10424..10909)
                     /locus_tag="PC465_002218"
     CDS             complement(10424..10909)
                     /locus_tag="PC465_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HDF2649511.1"
                     /translation="MNREIVVNIADMKIAYRPNVLVTYALGSCVGVCLIDKVAGIGGM
                     LHVMLPYSKDAINIENKCKFADTGINELIKSMENIGANRIYIKAKIAGGAQMFLGSSN
                     SVIASIGHRNVEAVKKTLLGLNIPILAEDTGMNYGRTIRFYTETGELLVDSINKGKKK
                     L"
     gene            complement(10906..11523)
                     /locus_tag="PC465_002219"
     CDS             complement(10906..11523)
                     /locus_tag="PC465_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HDF2649512.1"
                     /translation="MINYLELDDVHIDALREIGNIGSGNAITALASMINSNVEVLIPM
                     VKILEYNEATNLLGGPENKVVCILLDMKGDINGMFMFLLDESITQLMLSSLFNKEEAF
                     LDEIEAIEISAIKEIGNIMASSYVNAIASMLNMTISVSIPDICIDMVGAVLNVPMIRF
                     SDVGDKVLFIENKFKMSDNYFTSHILMIPEMSSLREILVRLGLEV"
     gene            complement(11588..11950)
                     /locus_tag="PC465_002220"
     CDS             complement(11588..11950)
                     /locus_tag="PC465_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDF2649513.1"
                     /translation="MENKILIVDDAIFMRMIIKEALSKSGYNNLIEANDGEEACNIFK
                     YEKPDLMLLDITMPKKDGLEVLREIKKLDSSAKVVMCSAIGQENMIVEAIKLGALDFI
                     VKPFKTETLVKVVNNVLK"
     gene            complement(12694..13191)
                     /locus_tag="PC465_002221"
     CDS             complement(12694..13191)
                     /locus_tag="PC465_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HDF2649514.1"
                     /translation="MNYEIVEINEKIVIGISKETTNKDGQAVNDIGELWKKFMGKGIY
                     NAIKGKKNDKTIGLYTDYQGDFTSPYSFVACCEVNSNSDKEKNLEELNTNNTVGESII
                     SKVIPAGKYAKFVIVGGQKEVGDFWFEFWQMDFDRTYISDFEEYQCNTFDTKKQEVHI
                     YIGIK"
     gene            complement(13366..14277)
                     /locus_tag="PC465_002222"
     CDS             complement(13366..14277)
                     /locus_tag="PC465_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HDF2649515.1"
                     /translation="MKINRLTEIIVILLNKKLVTAKELADRFEVSTRTIYRDIETLSM
                     SGVPVYMTKGKGGGISLIEEYSIDKAILSKKDKESLIVALKTLQATKYPEINSVVNKI
                     GSIFGEQNFSNWIEIDFTEWGSNFNEDDKFTKIKEAILRRNTINFNYVNSLSSQTNRT
                     VEPLKLMYKSKTWYLYGFCKLKDDFRIFRISRIRNLSIKDEVFSRKIIEEVCLNDSKV
                     IKENTITLKLRFKEKMLFRVFDDFNKDLITKNEDDTYDVITEFPIGEWIYGYILSFGD
                     NVEVLEPKDVRDNVITRLRELSKIYSL"
     gene            15247..16098
                     /locus_tag="PC465_002223"
     CDS             15247..16098
                     /locus_tag="PC465_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HDF2649516.1"
                     /translation="MEINKKHFIQVFLTCLILVVICEFIGQRTIAIGKASIVLFPMLY
                     AVIIGLIITPDLLGKKIKALKKVVGEKEINIAGEVVGIALVMLGIKYGTTVGPNIDKI
                     IQAGPAFIAQEFGHILAPIVALPLALMFGMKREAVGATASISREPSLGVISEKYGINS
                     PEGSGVLGTYLMGTVLGTIYFSVLGSISIYSGLHPYALGMACGVGSGSMMTAAAGSLS
                     TMVPPEMADTILAYAATSNMMSSITGIIFLVFVSLPFTNFMYKILEPKFSRNKKTKEI
                     KSTEGEC"
     gene            16102..16572
                     /locus_tag="PC465_002224"
     CDS             16102..16572
                     /locus_tag="PC465_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649517.1"
                     /translation="MFANLNLKKSSYQLLVMSVIGVIILIGQRISVGTSIVTALPGMV
                     MLILAAMAAMIIKDLFPKSIFPAFGFATIIGLLLSMPYSPTSEVFLTNTNNINFMAIT
                     TPLLAFAGISVGNKIEALKEMSWKIVIISLIVFTTIFFACASIAHIVLSIQGKI"
     gene            16585..17895
                     /locus_tag="PC465_002225"
     CDS             16585..17895
                     /locus_tag="PC465_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2649518.1"
                     /translation="MNKEQLKSLVIKTIDENREKILKIGQGIYKNPEYGYKEFKTTEA
                     VSNFFEQELNLSVEKNIAVTGCKADANSSKKGPHISILGELDGISCKEHKDANEIGAS
                     HTCGHNIQIAGMLGAAVGLVKSGVLEHLDGKVSFMATPAEEFIELEYREQLKKEGKIT
                     YFGGKQELIKRGYFDDIDISMMFHASDLGEDKALVGPESNGFVGKKVKFIGKESHAGS
                     APHDGINALNAAMLAINNVNALRETFKESERVRFHPIITKGGDIVNVVPADVHMESYV
                     RARTINGMIDANERINKALMAGGMAVGADVEITEIPGYLPILRYKSLDNLFKNNLEDL
                     GLKGKVIDGGDFTGSFDFGDVSHIMPTLHPMIGGVKGALHTRDFEIVDEDLAYIIPAK
                     AMALTVVDLLFDNAKDAKDILDTFTPVMTKEEYLTFLEKHDKTL"
     gene            18107..18853
                     /locus_tag="PC465_002226"
     CDS             18107..18853
                     /locus_tag="PC465_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2649519.1"
                     /translation="MFNAGNRIINTWLYPIQDGFVLIDTGYENGFKHFKKRISKFNIK
                     IKDIRYIFLTHAHDDHVGFLNQILDESPNTKIVMHDKALEILYKGQNSFIGGCTSRTA
                     FLFCQIMKLFGKGEHSFSPLKQEFEKRCILVSDKNRKEIEKELNGKIIDTPGHTADSI
                     SLLIDEGVLFCGDSAMNGFPSTHKITIFAESKLEFIQSWKTIINTKPKMIYPGHGKPF
                     ECSKLEQNLIYVNKINLYPLHNSKDIHRFL"
     gene            19215..20756
                     /locus_tag="PC465_002227"
     CDS             19215..20756
                     /locus_tag="PC465_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HDF2649520.1"
                     /translation="MNDNVVKKKNFFDRTLNRIETVGNKLPDPVTIFLGLCVLLLILS
                     SLVGSMGISVVHPGTGETITAVNLLTVEQLQILLGNIVSNFQGFAPLGLVLVTMIGAG
                     VCDKTGLMTATIKASVSKIPETRVTLVVMTIGMLANIASDAGTILFPPLAALVYLGVG
                     RHPLIGLFSGYAAVCLGFAANIMISVNDILAASFTVPAAQMIDSGFQANATMNLFFMI
                     ASTFVLILLATWVTEKIVAPRFGKYEGNAELDVDGSLSDVEKKGLKKAGISILIYVAI
                     IVALSVIGKKPFLADPETGDLLSNNAPLMKGMVPIIALAFFIPGVVYGKTIGKIKKDK
                     DVVSIMASAMSDMGGYIILAFAASQFLQLFTNSNLGLILAVKGGEFLKSAGINGPLLL
                     IGFIILSCFINLFIGSASAKWAILAPIFVPMFMMVGYNPALTQMAYRIGDCITNPLSP
                     LFPYFPIILAFTRKYDKDAGMGTVIANMIPYSISFLIVWTILLILFMVFNIPLGPGIL
                     PSYSM"
     gene            20791..21897
                     /locus_tag="PC465_002228"
     CDS             20791..21897
                     /locus_tag="PC465_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF2649521.1"
                     /translation="MLDKNRLINNFMDMVRIDSPSNQELEMSKWLVNYLKERNIDAII
                     DDAGEKYGGNTGNVIAYIKGEEGSRPLCLCAHMDQVQPCLGVKPILDGNVVRSDGTTT
                     LGADDKAGIAAILEALEHVITEKIPHRDIYLCFTICEEAGMHGVKNFNPDNLPCKDMV
                     ILDSGGAIGSIAYKAPAQQSIKISFHGKKAHAGIEPEKGLNAILVASHAISNMHIGRI
                     DSLTTSNIGKIEGGGATNIVTDKVTLTAEIRSHIPETLEYELNHMEKCCKDAASKFNT
                     TYTFEHNMSYPSFELSRDSHVFKLSEEAIRQVGIVPNPMVIGGGSDANILANLGYNCA
                     ILSLGMYDVHTVNEYVNIDELYDTAKIVYHMIKL"
     gene            complement(22275..23561)
                     /locus_tag="PC465_002229"
     CDS             complement(22275..23561)
                     /locus_tag="PC465_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2649522.1"
                     /translation="MIVGIIGPSDSGFKIKDDLKQIDSDLKTKIYVREKVVDTIEVIS
                     KCEDECDAIIFTGCAVYEFIKSKYEISKPHSFVPRSGTSIMKAFWAIKSANIKLDKFS
                     IDVVDRYVVEDALKEFDIKATSVFCNPFSLEVGESELVEWHIKLFEENKTDIMLTGFG
                     AVYNELKERGYPVFRLQATIQLIKESYDKVKSEYALSKARFSQIAVEILSLIDYKEKI
                     DNYYSDMIKKSDMDKLVVNYVRSIQGSLFLLGRNDYVVFVHKGVADNEYNYDKLFNLK
                     REIKDMGFSLSIGIGTGVTAYQAENNAHKALRHSIDSKEIGIYLVDEDENIRGPLASE
                     NELNYSLMLSDEKVIEISKKTGMSCESVAKIIAINENRKSKIYDSKELAEYLNVSERS
                     ARRILNKIVNAGLGRICAKETSIGGGRPKNITEILF"
     gene            complement(23684..26782)
                     /locus_tag="PC465_002230"
     CDS             complement(23684..26782)
                     /locus_tag="PC465_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF2649523.1"
                     /translation="MDVINLIDELDEIVYVSSLDTYELLYINEIGKKAMGLNDISHLK
                     CYKALQGKDSPCEFCTNSILKEDEYYIWENTNTRTNRHFILKDKLIKWEGKHARLEIA
                     LDITEKEDISKSIAEKLEIKELLVGCIKHLITESNFSDAVNLVLTNIGKFHKADRAYV
                     FEVSEDRTKVTNTYEWCNEGVDEQKQALTNLDINELKNWFLLFEQKGFVIIDDIENIK
                     EEQPIEYEILKPQKIESLMTSSLKQDDKVVGFIGVDNPHKAVGDTSLLTSLSYFLLTE
                     MKKRKVENKLNYMSYYDFLTGAYNRNKYIKYIDNFQKGKVKSIGVVFVDINGLKDIND
                     NFGHANGDSAIVSACVIIKKYFHSYNVYRIGGDEFVVLCEDISKQLFEELVSWLSEEF
                     KDEMIYSVAVGSIWSDDNIDIHKLIKVADERMYQDKKRYYNKNKLRNNEMKVISDLAD
                     STNNILFKHKELVDKVYFDDLMIKGYSKAYEKLAYNTYDIILSICIDTNLITPIYQSE
                     SNIFSFPIKENLEKTFSYIKKYLIHPDDIILFNDNHLLKSLDSLNNSKQDDLELNFEY
                     RRLGIDKKYYWALIYMLKISSKNKLGEKQTHILVAIKNIDYLMQLHKNQKDTLTGLYN
                     YESFCEQISLMLKRYPDKRYAIIMMDIDKFKVINDIYGVRGGDKALIYVAELIQKNIG
                     SNGICCRMYADVFCIFYESYSDRDIHKVIYKIKNSLNRKKFEYMLVPCFGVYRILDNH
                     IPITNACEMAGYAHKKVKKQSINNYIFYDDTIRNDALEEKQMEREMEYALENGQFHVY
                     LQPKYNLNANKIVGAEALVRWVHPEKGIIPPIKFISLFEKNGFIIRLDMYVWEQVCSL
                     IRKWIDLGEEPVPISVNVSRLHLHNPHFKEIVLSLINKYSIPKSFLELELTESLFIKN
                     IKLFTKIIADLRMDGIVLNMDDFGSAYSSLNMLKNINIDTLKIDCGFFNEEGITDREK
                     IVLKHTIAMAKDLDMDVVAEGVETKEQAEFLVSLDCVVIQGYYYCKPIPSADFEKLLY
                     QK"
     gene            27486..27638
                     /locus_tag="PC465_002231"
     CDS             27486..27638
                     /locus_tag="PC465_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649524.1"
                     /translation="MKIFSFLLFVVGICFCIAGFMGHSSAFSGATLSFFATTMIAVRQ
                     VKTKKK"
     gene            complement(27930..28634)
                     /locus_tag="PC465_002232"
     CDS             complement(27930..28634)
                     /locus_tag="PC465_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2649525.1"
                     /translation="MEIKPLVLIVEDDKPICKFIKVSLETQNYRCVETDNGGTAISLI
                     HSLDPDLIILDLGLPDIDGIEVIGRVRACAKTNKIIVVSAREHERDKVEALDGGADDY
                     LTKPFSVTELLARVRVALRNKAQQDNINNDAPKSFEVKNLKIDYENHIVSINGEEIHL
                     TPIEYKIIELMSKYSGRVLTHKFIIDKVWGNYYESENQSLRVFMASIRRKIEKNPAQP
                     EYILTEVGVGYRMADE"
     gene            complement(28625..30232)
                     /locus_tag="PC465_002233"
     CDS             complement(28625..30232)
                     /locus_tag="PC465_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HDF2649526.1"
                     /translation="MKKERLQHEDLKEYDYDEDGYLSKKIIIKDFIKTILVMTIATGI
                     SVVFEKVGFNESNIILVYILGVLFATSITYGYFFGILSSVIGVLSFNFFFTHPLYTFL
                     AYRKDYPMTFCIMLMAAIITSTLTSRIKREVRLSHKREKMIRLLYENNKTLLKAKNKN
                     QIIEFCGSNLVNILNRTVIVTIADENNNLGKPSIYICNNDGSENIFHSVLEKEAIKEA
                     FRTGNPVGIGTKYCKNSSAYYFPIKGQESNVLGVIGVACFKIDIITENEKILLEAVST
                     QVALAIDRENLFEKNKKANLEAERERLRGNLLRSISHDLRTPLTSILGSSSTILENDD
                     VIDKETRVELLKNIYEDTSWLTHSVENILSMTRIDEGKLDIEKRPEVVDEIIAESILR
                     VKKFANSRDIKTNIPDEIIIVHVDVLLIEQVLVNLIDNAIRHTPKNSKIELTVKKESN
                     QVLFEVADNGKGIPNEDIGNIFNRFYTKNKSRNLERRGIGLGLEICKSIVEAHGGEIV
                     AFNNPSGGATFRFSIPMYDEEGKDKWK"
     gene            complement(30486..31664)
                     /locus_tag="PC465_002234"
     CDS             complement(30486..31664)
                     /locus_tag="PC465_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649527.1"
                     /translation="MEKLSDKRRVKAVSMETFVFIVLLAVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLDTVFLIMAMAVLAGALSALLSEFGVISLVNKIFKGLMRPIWGLPGASIA
                     GVVATYLSDNPAIIPFAKDKTFTQYFKKYQVPALCNLGTAFGMGLIVTTFMIAQGKEY
                     VLPAIIGNVAAIIGSIISVRIMLTFTKKYYNYDPKNDTEKQINDKGAKLEEFREIRDG
                     NVFQRTLDAILEGGKLGVEMGMAIMPGVLVVCTLVMLLTFGPSTDPATGQAVYTGAAY
                     EGIKLLPAIGDKISFIIEPLFGFTSPEAIAFPVTALGAVGAAISLVPEFIKSGAITPN
                     DIAVFTAMGMCWSGYLSTHIGMMDALDARPLAGKAILSHTIGGLCAGICAHFIFMLVG
                     "
     gene            complement(31890..32384)
                     /locus_tag="PC465_002235"
     CDS             complement(31890..32384)
                     /locus_tag="PC465_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF2649528.1"
                     /translation="MHLFIEVIAAFFTALSFGVLFNMKGKNLILAGIGGSIAWFSYKF
                     LLNMGVTENLCFFIATVCFAIYCELCARIYMTPATTLSVCCLIILVPGYGIYNTMYSV
                     LTNNYIKAVEYGVSTLSCASSIALGLVFITTVFRKVNLYGVLTKIKENEKYKKSINKI
                     KQQK"
     gene            complement(32385..33146)
                     /locus_tag="PC465_002236"
     CDS             complement(32385..33146)
                     /locus_tag="PC465_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF2649529.1"
                     /translation="MDIDRILNFSSNAGKAMLQSGGETYRVEETIARICQSFGIDHVD
                     VFATPTAVMASVFVDGKLHSAIKRISSRRVDLNLVHEVNSLSRAISINNLDIELCEKI
                     LDEISEDNYYSDLITIFFAGIAAATFSILFGGNVEEFIAAFTVGILTKFVIMYLSKSS
                     LNDFFVNAIGAVIIASCSILILKLGFIKTLDHLIAGAIMLLVPGLALTNALRDLLDGQ
                     LISGLAKLAEVFFVGVSIAVGMFLVLGLYFKLGGI"
     gene            33848..36682
                     /locus_tag="PC465_002237"
     CDS             33848..36682
                     /locus_tag="PC465_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2649530.1"
                     /translation="MLRKDKVLLSLHKLCENMTLKDLQSDKTGFTTIEIANHSSLDRS
                     NTSKELNNLYNEKKVLKISSKPILFLHASIIENLIGRTLNSDEFSINNCNELLKSSKN
                     DSEDIFSTLLGHDSSLKLPIEKAKSAILYPPKGLNTLLIGPTGVGKSTFAETMYKYAV
                     ESKIFSSESKFVVFNCAEYAENANLLLSNLFGYVKGSFTGANKDKFGIVAQADGGILF
                     LDEIHRLPPEGQEMLFLLMDKGIYRRLGESDIVHKANVFIVCATTEDIHSSLLGTFLR
                     RIPVTINLPALQDRSLKERLSLIKYFFIIESKYTNATIKVHKDVIKSLLLYDCFGNIG
                     QLKSDIQLMSARAFLNYKTGLKDNIEIDLSLVPDYIYIGLLKLNENRSNLNKLSELDY
                     MLFYEFNGNNLEVEYTKELSKYNIDTSNNGFKYSTEIPYLENDIRSMFINYMEKYSTK
                     LLSISSVTHSDYTSNEIFKVINPKIYYAVEHSLKEAEKISRNKYTKQTYIALSMHISA
                     LIENINQDTYNPKYNLYNDKIFLDKDLNIAKIVLSIIENDLQTSLPKDEVKFISMFLN
                     SMYLEPNNQSESIGVIILAHGNSTASSMCDVANSLLGTNHCNAIDMPLDVKVSTILDK
                     TIELVKECDEGKGVLLLTDMGSLIAFGELISEKTKIKTRSIEMVSTPIVLEAVRKSTL
                     PEMTLDELANSLSSLNPYIGRAAIDLTEINYPEKSREYVIITTCITGYGSAMKVADFI
                     NSSLKNISKYNINLVPHNIESFKMYKNKFSNTKILAVVGSVDFNVANTPFIHIEELLN
                     GYGLDMLNKIIEGTFNANSITNIKETNLSYNSLIINFMTQNLELLDSVKLFNYVNSSL
                     FTIIELIDENLKSKFKLGYILHCSFMIERCFKNTTFPYNNITELISKNHELYSLIREA
                     FKPTEAYFNILIPDEEIAYIIDMINEYLNK"
     gene            36725..37969
                     /locus_tag="PC465_002238"
     CDS             36725..37969
                     /locus_tag="PC465_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF2649531.1"
                     /translation="MEDEILKGKIKQLTILALIFIFITPVFAFADTPPVPNSSRAALL
                     IDQETKRILFEKNIDEKMPLASLSKMMTFLLAIEAVDKNQVKETDMVKIDKSTASVGG
                     STCKLKDGDEISLGELMQGLMLVSGNDAAIAIAKHIGKTEKNFVNMMNKKAEEIGMID
                     TYYFNPNGLPIYTDPEHKEPPIENMSTAHDIVTLGKYMYDHYENQVTRITTMQVYNDT
                     KKDFTHYNTNPLLVSVPGVDGIKTGYTDNAGYCLAFSMMVPKDAKNERNHRLIGVVLG
                     DGNKKNRISSSATLLKYGKDNFHSKKIAHKGDIIETPCVDGIDDFKITVKVDKDLYGV
                     VSDNENINPKVVFKNMNYPIHKGDIVGVAKYYNDSGKFVGSVDVKSESNIGCIPLKDK
                     IKIKVAKINKKLEIKNSVCFKA"
BASE COUNT        12950 a         6430 c         4476 g        14681 t
ORIGIN      
        1 taaaataaac tatcttccaa acattttatt atatgcttaa aagatagttt tgtgtcttta
       61 aaataaatta aattgtatat attccttcac ataacttttg tatattacta ggtggttgcc
      121 atttaccatc ttttttagta tatgtaatca tagttgtaac ttccttagtt ggtttcttat
      181 tgtaaaggtc tataatcatt tttgtcatat catcttgaac ttctttttct tttttatcgt
      241 aattcttttc atcagttaca taagatttta ctaaagtgtt cgcttcactc attactttac
      301 tagtatctaa agctttactt acaactttca aagttatctt atccttacta gaagattcca
      361 ctgttactgt cttttcaaca ccttgaatta atttaacaat tgtttcgtat atcttttcag
      421 cattttcttt accataaaga ggtgtcaatt gagcaatcat tgaaaccttg tccttgctgt
      481 tataagtttg aatctgttta tattcagctt ctgttaatgc atcagaaatt cctttttcat
      541 catacttata catttctaat gcagctaaat tagcttcaaa attcgacttt actttttctt
      601 ctgcattaga acaccctata gttagaacta aaactagagc cataatcgta gataatatta
      661 acttttttac cattttcata caaacatcct ccctcaatta aaataataaa aaatttattt
      721 atcaacatta taacataaat ttgtctaact atagaattat tttgaatatt ttaccacttc
      781 cagtctattc caataccgtt ttcttttgct ttatcgtata ttctttttgc tgttacgaca
      841 tcttgtacac ctatcccaac agttttaaat acaattatct catcatcatc ttctcttcca
      901 ggaatagttc cgtttataac attccctaaa tcaccactaa aatcatcttt acttatctta
      961 ccttctttta atggaattaa tatatctcct gactcagata aaactgcatc tgttgattca
     1021 aaaaatatct tagacgctct agttaaacag tttgggcaca actcttgcat atctggcata
     1081 tatgaaccta ctgcacttat taaagctcct tttttcacta agtttccatt aagtactggt
     1141 tgttttgatg gagtagctaa aactatcaca tctgcgttat ctatggcttc atcagatgat
     1201 tcaactgcaa ctattttagt attatattta cttaatttta agttcatttc ttctgcaaat
     1261 ttttctctac tttccttgtt tctactaaaa actcttacct catccaaatt tctagcttct
     1321 atcatggctt caagttgtgg ctcaccttgt cctcctagac ctatcaaagc tccaatctta
     1381 gaatcttttt tagccaatac gtctatagct gctccagagg ctgctccagt acgaatctga
     1441 gttacataag taccatccaa tactgcacta acttctccag tttctccatc taataatagt
     1501 actgttgctg gaattactgg tttgcctttt tgagcatttt taggaaatac agatacaatt
     1561 tttattcccc cacagcctaa ttcttctacg tatcctggca taaataacat actagcatct
     1621 tgacttggaa cagatatatt ggttctcaaa ggatttacac tctttccttc acaataaatt
     1681 ctaaaagctt ccttatcagc ttcaattgca tctctcattg taaatacttt ttttatgtcg
     1741 tcttttttta aaagtagcat ttttataccc ccaattttaa taagtctcta tgctaaatat
     1801 tatagcataa catttaattt aatcttctat ttcaaatcaa ataaatctac atactctggt
     1861 tttagcatag aacttatcaa cgctttattt attgaaaatt ctggtattcc tgctgcatat
     1921 ggagttatat catataaatc aaaatataca actagattct catcttgcaa gtaaaagttt
     1981 tgattctctt ttataccttt aaaattatat attccgatat tttcttcatc ctttttttca
     2041 agttcagcta tttgtctttt aatttcttca tctataactt ctttatattt agtattatcc
     2101 ttaaacaagt ccattaattc taaaaatttt ccagttctca tatccacatt atatgctata
     2161 tcttgataaa atccatgtgc tccaccacta taagtgtaat atctcacttt tatactaaga
     2221 gcagaatcag tattcttttt aagttcaaag tctacatttg caacaaactt atttttctcg
     2281 tcaggattat ccttaagata ctgctttgct tctttatatg atttattata aaattcaaat
     2341 atgtcatttt ttatcttatc atttgtagac ctttcaacaa ttttatttga atttgttatt
     2401 acaggcatgt ttatagtact ttctaaatac tcatcatttt tcactattgt tttacttcct
     2461 attgtactta ctgataaagt ttgtttacta tttgtattac cctttggtaa tgactggtta
     2521 ctcataacag tcactgcttc cttattacta tttaaattaa ttgaagcatc tttccttaaa
     2581 ttattatatt tatagtcatg tttaattgcc aaaacagcca ttatagtcaa tgttaaaaca
     2641 aatacatatc ttaaaacttt agcttttgta tcgactttaa aaaatttcat attatcattt
     2701 tcctcctaaa tataaatctc tcttattata tttggagttt ctagggtttt ttatccatat
     2761 aatttaataa aagattaatt tttatttata aaaaattaat ctttttgttt taaaatatta
     2821 atatgtctta tcaaacagtt tgaaatttca ccaagaggta attgtaacat aacagaacct
     2881 ctatcaaaag ctaccattgg cattccatat actatacaag aattttcatc ctgtccaatt
     2941 gtaaatgaac cattttcttt catttttaaa agtccacttg ctccatcata acccatacct
     3001 gtaagtatta ttcctattga atttttacct gctacttctg ctactgaatc aaacaaaacg
     3061 tctactgatg gacagtgacc acttattctt tctccttttt cacaagttac ataatatcct
     3121 tgtttatccg tacacaattt catctggtaa cccccaggtg caattaacac atttccttgt
     3181 tctactctat cattattctt agcttctctt acattcataa tacactgttt gtcaagccgt
     3241 tgtgcataca tataagtaaa catagctggc atatgttgaa ctacaacaat ccctggtgtt
     3301 gattttggta ggtcttttat aatttcaagt attgcctctg taccacctac agatgcgcct
     3361 atagcaataa ccatattatt aaaacgttcc acattaccgc ctccaaaaaa tcatatatca
     3421 aaaatacctt tttatcgttt atatatagca ggttttacat atttgtattt agtactactt
     3481 ctgttgatta cttctgcatg tcctacaaac aaaaaactat cttttttggt agcattataa
     3541 aatttattta taagttcttc tcttgttttt aaatcaaaat aaatcataac atttctacaa
     3601 aaaatcaaat caaaatgttg atatgagaaa tcattcatta aattaaacgg cttaaaaatt
     3661 acactttttc taatcttatc acaaatttta aatgtaccat ccttgttgtc tataaaatac
     3721 ttcttcttcc ataactcagg aacattgtta acatttgatt ctatgtatat acctctttta
     3781 gctttttcaa gtgagttagt tgaaatatct gtggctatga ttttaatgtt ccacaactct
     3841 ttattatatc caaaataatc atccaaagtc atagctattg aatacgcttc ttctccacta
     3901 gaacatcctg cactccatat atttatgttt cttattttat tattttcttc ccaaaaagga
     3961 agtatactat tctgtataaa ctcaaaatgt tgaggttctc tcataaaaaa tgtgtggtta
     4021 gtactcaatc tatttattag gtttatagct tcatttcctg tcttatcttt aaataataga
     4081 ttcatatatt gactaaaaga actaagtttt ttctctatca ttgtattgta taagcgacct
     4141 tcaattaacg ctcttttttt acttaaatca ataccatatt ctttttttac atggtttaca
     4201 agaactataa attcttcatc tgtgagtttt atcatgcaaa aacttcctcc tgctaattta
     4261 tcagaactaa ctatatgcta ttaatcaaaa actttcgaat atctaaaatt aatatagaat
     4321 tatcttcaac tttcgcaatc tcttttatat ctttattaat attagtgttg ttagaattag
     4381 tcgtctctag taaatttaga ttttctatat gaataacatc aacaacttta tctacaataa
     4441 ttccaacttg atactcatca acctttgtaa ttattataca agttctctca ttataatcag
     4501 ctttaggaag attgtacttt atatgcatat taataactgg tattattctt cctctcaaat
     4561 taataactcc acttatatat gttggaagac atggtacata cgttattgat tgaaatctta
     4621 tggtttcaat cacattttct aattctattc cataaataac atcattgaca taaaatgtta
     4681 atacttgttt aataatttca tctttagcca tactttaaat cccctaatat atttctataa
     4741 tgctatctgc atctataatt aaacttatac ttccatcccc aagtattgta catcccgata
     4801 aacccttatt ttttatatta aatcggttaa aataaactgg aaatggtttc acaacaactt
     4861 gctgattacc tattatttca tcaacaaaaa tgcatactgc tttatgctca ttttcaataa
     4921 ttatcatatt accattcatc agattggtta cttttgtttg aatattatat attttatgta
     4981 accttataat gggaatacat gctccatata ttgtaattaa ctctgtctta tttccttctg
     5041 taattatttg atttaagtct gtaagtttaa atgttcttct tatggatgat attggtaaag
     5101 taaatagtga atctccaact ttaaacttca taccctctac tatagaaaga gttaatggta
     5161 tttttatagt aaaggttgtc ccctcatcct gtttactttt tacttcaatt gaacctccaa
     5221 ctttttcaat acttttacga acaatgtcca tgcctactcc tcttccagaa aattcagtta
     5281 tagattcttt tgtagaaaag cctggagtca taatcaaaga attgacctcg tcatcagtat
     5341 actcattact ttgatgttta agaagacctt gttccttagc ttttgccaaa atcttatctc
     5401 tcataatgcc tctaccatca tctgaaatac ttatcacagc ttctccgcct agattttcag
     5461 cagataaaac tatctttccc acttcttctt tacctttcgc tatacgctcc tcaataggct
     5521 ctattgcatg gtccatagca tttcttataa ggtgcataaa gggttctgct aaattatcaa
     5581 ttacactctt atctacctct gtctctgctc ctatagttat taactctaca tttttatcta
     5641 attttttatt catatctcgt acaattctat gcattttttg aaatacacca gcaatttgaa
     5701 tcatacgcat agacattact atatcttgca attcatctgt aagcttgtgt aattgtcttg
     5761 ttgccttatt gaaattatct atatcaacac ctgtagaatt tacgctattt acaaccattg
     5821 attccataat tacaatttct ccaactatat tttgaagtaa gtccaatttt tctaaattta
     5881 cactcataat actctgctta cttattggta aatgttcatt gtcttcactt agactatctt
     5941 tttccatatc agttttttca tttaaaacat cttcttgtat ctcatcttct gtatagttat
     6001 tttgataact tttacttact ttattattat cttttaattt attttctact gcatcattgt
     6061 ttgatgtatt tttcatttct atttcttttt tactaatatt tatgtattct tttacataga
     6121 gattatcttc tatagtttta taaactattg ccttatcctc tttagctaca aattgtatat
     6181 aaaacccata acttttaata tactctgtag actctgcatt tgtttctaca tcttttggat
     6241 aaaaatctat aaattcacag taatctctaa gttcaaatac aagcatgaaa gctctcacat
     6301 tttccatcat gcaaccttgt tcaaagatta tttttactac atcagagtct tctttgtatt
     6361 caaaatttga atctattact tctttttcgt ctttactttc taaatttgca ttatcctttg
     6421 atttcataga acttgataat tccaaagtac tcacatactc ttcaattcct tcaataaaat
     6481 tagagtaatc agaagatata caacctcttg attgtaactc atctatatct cttcttataa
     6541 aatctaatga ttgaaagact aaatcaaata ataggtcatt gtctaaaact tctattttac
     6601 cttcacgtat agcataaaac aagtcttcta cactatgtgc taaagcagat atattgtcta
     6661 accccatcat agatgctgaa ccttttatcg tatgcattat tctaaaagtt tcattaatgt
     6721 tgttatgagt aaatactttc tctttttcta tttgaatcat aatttcatct aattgttcga
     6781 gtaataaact tgtctcaaat ataaacatat ctaacatttg tctcatactc ggttcaatat
     6841 aattcacatt tatcacctac gacctacaaa taattttcta ttatatatgc atctcataat
     6901 ttaaatcctt gatgattctc ttatctcact atatgtacct cataatttaa atacacaatc
     6961 attctcttat ttcaatatat atacatctca taatttaaat acacgataat tctcttactt
     7021 caatattcac ctcataattt aaacccatga tgattctctt acttcacttt cctttagatg
     7081 aaatttttct actaattctt ttaaaatttg agcttgagca gacatctctt ctgaagctgc
     7141 tgcactttcc tctgctgttg ctgagttcat ttggactact atggaaattt gctctattcc
     7201 agataaaatc tgtgtaattg ctacttcttg actatgtaca gccgaagaaa taccattaat
     7261 ataattagta gttttttcta caccatttac taccaagtcc aatgcatttg cagtctcttt
     7321 agcaattctg acaccatttt ctactgtttt aatagcttct tctatgagaa tagctgtatt
     7381 ttgagctgct tttgcacttt taccagccaa agacctaact tcatctgcta caactgcaaa
     7441 tcctctacca tattgacctg ctcttgctgc ttcaacagct gcatttaatg caagaatatt
     7501 agtttggaat gctatctcat ctattgtttt gattattttt gatatttcac tcgatttttc
     7561 acttatttca cccattgatg tcatcatatc atccatacat ctacttccga aaccaacttg
     7621 tgatgcagat tggtcagata cctcacatgc aagactagca ctatctgcac acttcttaat
     7681 tccatctgat atctcattaa tcgtggaagc taattcttct actgaactag cttgttcagt
     7741 agcaccctgt gaaagagctt gtgcacctgc tgcaacttgt tctgaagcac ttgcaacttg
     7801 ctctgctgat aaatttattt cagaaaaatc accattaaaa gagtttatta tactttctaa
     7861 agatatttta attgatttaa aatcacctat aaattcttgg tctatctcta ctcttaaatc
     7921 tccttttgca atactagtta atgtactgtc tataaggtct atgtaattta aaagcatact
     7981 ttgcatcttt ttgacagaac tcactaatag ccctatttca gatttacttt cttcaacgtc
     8041 tatacttgtt cttaagtccc cagatgcaat tcttgaaaag tgtttttcta ctttattaat
     8101 aggaatcact atttttaatt ttattactgt atattctatt attgtcaata ttattaaaag
     8161 ggaaagtata aatattgttc ttaatattag actttgtaat tcttttttta cttctacaat
     8221 tttggaattt gaacgggtaa ctatatcctc ttgaaattca tttattaaag aatccatttt
     8281 ctcttgggag tttatatagt cactaccaaa aattatactt tgagctttac tcttatcatt
     8341 actttcgact gcctttattg cactttgttc tgttggtact aaagaatctg atatttcttt
     8401 tgcttctaag attttatttg actcgctctt tgtaagacca attttttcta atttgtttaa
     8461 agctgattct cttgtttttc cgtataattc tttttcataa atatctttat tctttttttc
     8521 tcctgtaaat acatatcttc ttaatacatc acttatctct ctagttgtat cttttatata
     8581 ctgactttga gtcctcaaat tattcatatc attaatactt ttttctactt tttcaaatgc
     8641 tttataagat gaaatagaag aaaaaatccc tgctagaaca gccaatacta taataatcaa
     8701 caatacaatt gctaatttag aaagctttac ttctcttttc atatctgtac tccttcataa
     8761 agtaagttta tatctttttt aatcctttca ttgtactcac tacgctacaa tcttttccta
     8821 agtttttacc ctcatacatt gctttatctg ctaaggatat gttttcttct aatgatatat
     8881 ttgagtttac ttctactact cctaatgtaa tagtgcactt tattttatgt tctttatagt
     8941 tgaaatcaaa ctcctttatc tctttacgga ttctttctga aagtatctta gcaccttcta
     9001 ttggagtatt tgtgagcatt atcaaaaact cttctccacc ccatcttgat acagtatcaa
     9061 tttgtctaca attctttttt attatacttg atattactgt taacacgaaa tcccctgctt
     9121 catgcccata agtatcattg ataaccttaa agtcatcaat atcaccaagg ataagggata
     9181 ttgatgtttc actatattta ttaattcttc tttgctccat aagctgatta attatatgtc
     9241 gcctattgta aagacctgta agataatctc ttacaacgag tctattcaat ttttcaagag
     9301 aagattccag ttcattattt atctttttta atttatcttg agatttcttt acttcaagat
     9361 gagctataac acgagctttt aattctgtca tactaaaagg tttcaccata tagtcaattg
     9421 ctcctacacc aaatcctttt actatgtctg tatctgtatt ttttgaagtt ataaaaatta
     9481 taggtatatc tgctgtacga gcattagatt ttacttcctt acaaaactca aaaccagagt
     9541 tatctggtaa aattatatca agcaaaataa tgtctggtat aaattcttca ataaattctt
     9601 ttgcctctat tgcattaaat gcttttttaa ccttaaaatt atcttttgta agtgttttat
     9661 ctattaagtc acacatcaga acactatcat caacgactaa aattgttccc tgttgcttat
     9721 ttttcatata caaacctctc ttaaacataa tatattcaaa ttttaatgat ttaaaatttt
     9781 tatacttaat aattatacca ctatattctt aaatgttctc atcacaatct ttttataata
     9841 acactccaac tacatcccta tattacatga tagtgcaatc aaacccattg attaattcat
     9901 ctattaaaac ttcatcttta tctgtcaaaa gtttctctaa atctagtaaa gtaattattt
     9961 taccttctaa ttctccaact ccacttacaa aataatccga atattctata gtaactcttg
    10021 gtggaggtga tattttactt ttttctaagc ttactatatc atcaactcta tcaaccacaa
    10081 atccaactac caagtccttt atttcagtta ctactatata catgcaattt gtagtcatta
    10141 attcatcttt tttaagtctc aaactcatat ctattatcgg aatgattttt cctcttagat
    10201 ttattatgcc tttagaatat gtaggtagtt ctggaataaa tataatttct tgatttccag
    10261 taatttctat taccttttca agttcaaccc caaaatcttg ctcatctact ttaaacttta
    10321 gatacttaat tccttcatca attagtccat aatctaaata tgggtcatct ggaaatctca
    10381 tttaatacct ccctcctaaa atacactttc tatgaaatat atattataat ttcttcttac
    10441 ctttatttat tgaatctaca agtaattcac ccgtctcagt gtaaaaacgt attgttctac
    10501 cataattcat acctgtgtcc tcagctaata ttggaatatt taatcctaaa agagtttttt
    10561 ttactgcctc aacattccta tgtcctatac ttgcaattac tgaattgcta cttcctaaaa
    10621 acatctgagc acctccagca atttttgctt ttatatatat tctatttgca cctatattct
    10681 ccatagattt aatgagctca tttattcctg tgtcagcaaa tttacactta ttttcaatgt
    10741 taatagcatc tttactatat ggcaacataa cgtgtaacat tccaccaatt ccagctactt
    10801 tatctatcaa acatactcct acacaagaac caagtgcata agtaactaaa acatttggtc
    10861 tataggctat cttcatatct gcaatgttca ctactatctc tctattcata cttctaatcc
    10921 caacctcacg agtatttctc taagtgagct catttctgga atcatcaaaa tgtgactagt
    10981 aaaataatta tcactcattt taaatttatt ttctataaat aagactttgt caccaacatc
    11041 tgaaaatctt atcataggca catttagaac agctccaacc atatcaatac atatatctgg
    11101 aattgaaaca cttatagtca tgtttaacat agatgcaata gcatttacat atgaacttgc
    11161 cataatattt cctatttcct taattgctga aatttcaatt gcctcaatct catctaaaaa
    11221 agcttcttct ttattaaaaa gagaacttag cataagttga gttattgatt catccaacaa
    11281 aaacataaac attccattga tatcaccttt catatcgagt aaaatacata ctactttgtt
    11341 ttctggacca ccaagcaaat ttgtcgcttc attatattca agtatcttga ccataggtat
    11401 taatacttct acattgctat ttatcatgga tgcaagtgca gtaattgcat tcccagagcc
    11461 tatattacca atttctctaa gagcatctat atgaacatca tcaagttcta aataatttat
    11521 aatataaacc cctcccttta ttattgcatt tatttacttt tcattgtatt agtgtatatt
    11581 tacactttta ttttaaaaca ttatttacaa ctttaactaa tgtttctgtt ttgaagggct
    11641 tcactataaa atctaacgct ccaagtttta tggcttctac aatcatattc tcttgtccta
    11701 ttgcagagca cattacaacc ttagcacttg aatccaactt ttttatttct cttagcacct
    11761 ctaaaccatc tttttttggc attgtaatat caagcaacat caaatcaggc ttttcatatt
    11821 taaatatatt acacgcttct tctccatcat ttgcttctat taaattatta tagccacttt
    11881 tactcagagc ttctttaatt atcattctca taaaaatagc atcatctact atcaaaattt
    11941 tattttccat aaaactaact cctccatatg tacaacaata aacgctttta tcttcagtta
    12001 ttgtctatac tatctgacta tttttcgcta cacaataaat acatttcatt gataaataaa
    12061 agtaattatt tatgccatat tatacttaat tctcttaaca taatttgtca acaaaaaaac
    12121 ttatatatct attgtaatat atgtttggcg ttttgacgag ttattaaaaa tataattgta
    12181 taaaacataa aaagttatca aaagtaatta aattataata aaacaacttt ataccttttt
    12241 tatgtttgta taaaaaaaat tttcagattc attaaaatca tttctgtaga ttcatatagg
    12301 atttgacttt ctcaatatct aatagatagt tgtttattta cttaattata tttctctata
    12361 tgtattatcg attaaattag atttagcttt atacattatt ttttatattt ttcaaattgt
    12421 atacccataa atccagaagt attctaatgt gtttataata ctttttttca tattttaaac
    12481 taaataacaa atcattatat ttacaagtat catttatcaa taaacaatat taaatgaaga
    12541 atatgtctga agattcaaag tgatactgat actattaatt actaaaaaag cagtaaatct
    12601 tttacagatt tactgcttat agttataaat aataaaacta tctataataa atgtactata
    12661 ctcaatactt cattcaatat agtaataaca aatctacttt attcctatat aaatatgaac
    12721 ttcttgtttc tttgtatcaa aagtattaca ttgatactct tcaaaatcac ttatataagt
    12781 cctatcaaaa tccatttgcc aaaactcaaa ccaaaaatct cctacttctt tttgacctcc
    12841 tactataaca aactttgcat acttacctgc tggtataact ttactaataa tactttctcc
    12901 aacagtatta ttagtgttta attcttctaa attcttctct ttatcagaat tactatttac
    12961 ttcacaacat gcaacaaagc tatacggact tgtaaaatca ccctggtaat ctgtatatag
    13021 acctattgtc ttgtcattct ttttaccctt tatagcatta tatatccctt tgcccataaa
    13081 ttttttccac aattcaccta tatcatttac cgcttgtcca tctttatttg tagtctcctt
    13141 cgatattcct ataactattt tctcatttat ctctactatt tcataattca tactttatac
    13201 ctcactttgt ttttattaat atattttatt ttgaactaat tcaattataa tttataatat
    13261 acgacacctt tatgtcatat ttttaatata attaaactca gtgagatatt atatactaaa
    13321 tgcaagatat tatatattta ataaaatctt taatctagca ttatattata atgaataaat
    13381 tttagacaac tcccttagtc tagttattac attatcccta acatctttag gttcaagtac
    13441 ttcaacattg tcaccaaacg ataaaatata tccataaatc cattcaccaa taggaaattc
    13501 tgtaattaca tcatatgtat catcttcatt tttagttatt aaatccttat taaaatcatc
    13561 aaatactcta aaaagcatct tttctttaaa cctcaatttc aacgttatag tattttcctt
    13621 aattacttta gaatcattca aacatacttc ttctattatc tttcttgaaa acacttcatc
    13681 ctttatagat aaattcctta tcctactaat tctaaatatc ctaaaatcat cttttagttt
    13741 acaaaatcca tacaagtacc aagtcttact cttatacata agcttcagtg gttcgacagt
    13801 tctgtttgtc tggcttgaca aactatttac ataattaaaa tttatagtat tacgccttaa
    13861 aatagcttct tttatttttg taaatttatc atcttcatta aaattacttc cccattcagt
    13921 aaagtctatt tcaatccagt ttgaaaaatt ctgctctcca aatattgagc caattttatt
    13981 tactactgaa tttatttctg gatacttagt cgcctgtaat gttttcagtg caactattaa
    14041 actctcttta tctttttttg acaatatagc cttgtctata gaatattctt ctattaaaga
    14101 tatccctcct cctttgcctt tcgtcatata tactggtact cccgacatag acagagtttc
    14161 tatatctcta tatatggttc ttgtagaaac ttcaaaccta tctgccaact ctttagctgt
    14221 tactaatttt ttatttaata gaattactat tatttctgtt aatctattta ttttcattca
    14281 ttaccaccta ctaaaattat taaatttatt taatctaaat taatcatact aatttttaaa
    14341 taaacaaaat cttagaatct tatctaaatt attcttacat gattttattt actttctatt
    14401 atctttctca ctttggatat tatcatctta atttatttat tactatatca atttacttat
    14461 tatcatctca tttgttatcg tcttacttaa tttacttatt gctatatcaa ttccacttat
    14521 tatcatctta tttaacttac ttatttctat atcaattcac ttattattac ctcacttgtt
    14581 atcatcttac ttaatttact tatttctata tcaatttact tattatcatc tcatttgtta
    14641 tcgtcttact taatttactt attgctatgt caattcattt attattatct cacttgttat
    14701 cgtcttactt aatttactta tttctatatc aattcactta ttatcatctt aattcatttg
    14761 attattatca tttactttat tcaatttcta tatcaaaaat tagtatttgt acttaatact
    14821 taaaattaat ttaaagtctt tacatattat ttatttttta ttgtaatatt catttccata
    14881 ctttactaag ctacttccac tcatttattt taaaatttca atttactatt tctcaattct
    14941 atattattat ttttcaattt tatattacta attttaaagc tttttagcta ttattcctac
    15001 aatatttaaa caattttttc ataataaagc tatattacaa tatattcaaa atatgtaata
    15061 ttttagatat ttttcgttga caatgttaaa tttttgtttt atccttaatt aaggacatgt
    15121 tattgacatt tctgaaactt atttgaaata gttttttcat tttatttagg aaaacgtatt
    15181 atacttaaga aaacgtattt tctcatttca gataagtaaa atatttattc ttttgaggag
    15241 gaaatcatgg aaattaataa aaaacatttt attcaagtat ttttaacttg cttaatcttg
    15301 gtagtaatat gtgaatttat agggcaaaga actatagcta ttggaaaagc ctctatagta
    15361 ctgttcccta tgctttatgc agttataatt ggacttataa taacaccaga tttattaggt
    15421 aaaaaaatta aagcgcttaa aaaagtggtt ggagaaaaag aaataaatat tgctggtgaa
    15481 gttgttggaa ttgcactagt aatgcttggt ataaaatatg gtactacagt tggaccaaac
    15541 attgacaaaa taattcaagc tggaccagcg tttatcgctc aagaatttgg tcatatactt
    15601 gcaccaatcg ttgcattacc tcttgcatta atgtttggaa tgaaaagaga agctgttgga
    15661 gctactgcaa gtataagtcg tgaaccttct ttaggagtta tatcagaaaa atatgggata
    15721 aactcaccag aaggtagtgg tgtacttggt acatatttaa tgggaacagt tcttggtact
    15781 atatacttta gtgtactagg ttcaatatct atttatagtg gtcttcaccc atatgctttg
    15841 ggaatggcct gtggtgttgg tagtggaagt atgatgacag cagctgctgg ttcattatct
    15901 accatggtac cacctgaaat ggcagataca atacttgcct atgctgcaac aagcaatatg
    15961 atgtctagta taacaggaat tatattctta gtttttgtgt ccttaccatt tactaatttt
    16021 atgtataaga ttttagaacc aaaattttcg agaaataaaa aaactaaaga aattaaatct
    16081 acagaaggag agtgctaata aatgtttgct aatttaaatt taaagaaaag ttcatatcaa
    16141 ttattggtta tgtctgttat tggagttata attcttatag gacaaagaat tagcgttggt
    16201 acatctatag ttacagctct tcctggtatg gtgatgctaa tattagctgc tatggcagct
    16261 atgattataa aagatttatt tcctaaatca atctttccag cttttggatt tgcaactata
    16321 atcggccttt tacttagtat gccatatagt ccaacatctg aagtattctt aactaacact
    16381 aataatatta actttatggc tataactact ccactactag cttttgcagg aatttctgtt
    16441 ggaaacaaaa tagaagcttt aaaagaaatg tcatggaaaa tagttataat ttcacttatt
    16501 gtatttacaa ctatattctt tgcatgtgcg agtatagctc atatagtttt aagtattcaa
    16561 ggtaaaatat aggaggaatt tattatgaat aaagaacaat taaaatctct agtaataaaa
    16621 actatagatg aaaatagaga aaaaatatta aaaataggtc aaggaatata caaaaatcca
    16681 gaatatggat ataaagaatt taaaactaca gaagctgttt caaacttttt tgagcaagaa
    16741 ttaaatttat ctgtagaaaa aaatatagca gttacaggat gcaaagcaga tgcaaattct
    16801 agcaagaaag gtcctcatat atctatactt ggagaattgg atggtatctc atgtaaagaa
    16861 cataaagatg ctaatgaaat aggtgcttct catacttgtg gacataatat tcagatagct
    16921 ggaatgttag gtgctgctgt tggtttagta aaaagtggcg ttttagaaca tttagatggt
    16981 aaagtatctt ttatggctac tcctgctgaa gagtttattg agttggaata cagagagcaa
    17041 ttaaaaaaag aaggaaaaat aacttatttt ggtggaaaac aagaattaat aaaaagaggt
    17101 tattttgatg atatagacat atctatgatg tttcatgctt ctgatttagg agaagataag
    17161 gctctagttg gtcctgagag taatggattt gttggaaaaa aggttaaatt tataggtaaa
    17221 gaatctcatg ctggttctgc tccacatgat ggaataaatg ctttaaatgc agcaatgctt
    17281 gctataaaca acgtgaatgc acttagagaa acttttaaag agtctgaaag agttagattc
    17341 caccctatca tcacaaaagg tggagatata gtaaatgttg ttcctgctga tgttcatatg
    17401 gaatcatatg ttagagctag aactataaat ggtatgattg atgctaatga aagaataaat
    17461 aaggctttga tggctggtgg aatggcagtt ggagctgatg ttgagataac tgaaattcct
    17521 ggatatcttc caatattacg atacaaaagt cttgataatt tatttaaaaa caatcttgaa
    17581 gatttaggtc taaaaggaaa agttattgat ggtggagatt ttacaggctc ttttgatttt
    17641 ggagatgtgt ctcatataat gcctactctt caccctatga ttggtggtgt aaaaggagct
    17701 cttcatacaa gagattttga aatagttgat gaagatttag cttacataat tcctgctaaa
    17761 gcaatggcac ttacagttgt agaccttctt tttgataatg ctaaggatgc taaagatata
    17821 ttagatacct ttactccagt tatgactaaa gaagaatatc taacattctt agaaaaacac
    17881 gataaaactt tataagtcta tttttataat agggtggtat ctactgtaaa agttatacca
    17941 ctctttgttt ttgtaacagt atacttcttt tcttttagtt tttagattaa actaaaatat
    18001 attatcctcc ttaaaacttt tagagctacg ttgaaatatc agtagaacta tgctatattc
    18061 tttctaatta atataaattt ctattctaat tcaaggtggt gaaaaaatgt ttaatgcagg
    18121 aaatcgaatt ataaatacat ggttgtaccc tattcaagat ggctttgtct tgattgatac
    18181 tggatatgaa aatggtttta aacatttcaa aaaacgaatt tctaaattca acataaaaat
    18241 caaagatatt cgatacatat ttctaactca tgctcatgat gaccatgttg gttttctaaa
    18301 tcagattcta gacgaatctc ctaatacaaa gattgttatg catgataaag ctttagaaat
    18361 tctatataaa ggtcaaaact cttttattgg tggttgtacc agccgtactg cctttctctt
    18421 ttgccaaatt atgaaactat ttggaaaagg tgagcatagt ttttctccac ttaaacaaga
    18481 atttgaaaaa aggtgtattc ttgtgtctga caagaatcgt aaagaaattg aaaaagaact
    18541 aaatggaaaa attatagata caccaggaca tactgctgat tcaatttcac tactaattga
    18601 tgaaggtgtt ttattttgtg gagattctgc aatgaatgga tttccaagta ctcacaaaat
    18661 taccatattt gcagaaagca aactagaatt tattcaatct tggaaaacaa tcatcaatac
    18721 aaaacctaaa atgatttatc ctggacatgg aaaaccattt gaatgcagta aattagaaca
    18781 aaatctaatc tatgtaaata aaataaattt atatcctcta cataattcaa aagatattca
    18841 cagatttttg tagaaaatac aaagtaaatt tctttgatta attaaaaaat ctaacacttt
    18901 actacgctac ttattttaat aacttaatct tccactagct tttcataaaa ttttgtttta
    18961 aaattaattt taaagtgcat atgttattta aatacattag ataaaattcg tcattaatct
    19021 acttaaagca tatttaacta acaccactca accagaaaat tcagaaaact gcattgacac
    19081 aggaaaaagt ttattttata ctttttttag gacatattgt ggacacgtct taaatcgaca
    19141 agcagaattt atattgtaag attaaccaca atacttattt tttaattata tttttaaaca
    19201 ttagggagga tattatgaat gataacgtag ttaagaagaa aaactttttt gacaggacat
    19261 taaacagaat agaaactgtt ggtaataaac taccagaccc agttacaata tttttagggt
    19321 tatgtgtact tttacttata ctatctagtc tagttggttc tatgggtata tcagtagttc
    19381 atcctggtac tggagaaact ataaccgctg taaatttatt gactgtagaa cagcttcaaa
    19441 ttcttttagg aaacatagtc agcaatttcc aagggtttgc tcctttgggt ctagttctag
    19501 taactatgat aggtgctggt gtatgtgaca aaacaggact tatgacagca acaatcaaag
    19561 catcagtaag caagattcct gaaacaagag taactcttgt tgtaatgact ataggtatgc
    19621 ttgccaatat agcttcagat gcaggtacaa tattatttcc accattagct gcacttgtat
    19681 atcttggtgt tggtagacat ccacttatag gtttattttc tggatatgca gcagtctgtc
    19741 taggatttgc cgcaaacatt atgataagtg tcaatgatat acttgctgca agttttacag
    19801 ttccagcagc tcaaatgatt gattctggat ttcaagccaa tgcaacaatg aacttatttt
    19861 ttatgatagc atcaactttt gttctaatac ttttggcaac atgggtaaca gaaaaaattg
    19921 tagctcctag atttggtaaa tatgaaggaa atgcagaact agatgttgat ggaagtctta
    19981 gtgatgtaga aaagaaaggg cttaaaaaag ctggtataag tatattaata tatgtggcta
    20041 ttatagtagc tcttagtgta atcggtaaaa aaccattctt agctgaccca gaaacaggag
    20101 atttactatc aaacaatgct cctcttatga aaggtatggt acctataata gcactagcat
    20161 ttttcatacc tggtgttgta tacggaaaaa ctataggtaa aataaagaag gataaggatg
    20221 tagtctctat aatggctagt gcaatgagtg atatgggtgg atatataata ctagcatttg
    20281 ctgcttcaca atttttgcaa ttattcacaa atagtaattt aggtctgata ctagctgtaa
    20341 agggcggaga atttttaaaa tcagcaggaa taaatggacc tttattgttg ataggattta
    20401 ttatattatc atgttttata aatttattta taggtagtgc atctgcaaag tgggctattc
    20461 ttgcacctat atttgtacca atgtttatga tggttggata caatccagca cttactcaga
    20521 tggcttatcg tataggtgat tgtataacaa atccacttag cccattattt ccgtacttcc
    20581 ctattatact agcattcaca agaaaatacg ataaagatgc tggtatgggt actgtaattg
    20641 ctaatatgat accatactct atatcattct taatagtgtg gactatacta ctaatattgt
    20701 ttatggtatt taatattcca ctaggacctg gaatacttcc ttcatatagc atgtaattta
    20761 tttaaatctt tctaaaagga gaaataattt atgttagata aaaatagact tataaataat
    20821 tttatggata tggttagaat tgatagccca tctaatcaag aattagaaat gtctaagtgg
    20881 ttggtaaact acttaaaaga aagaaatata gacgccatta tagatgatgc aggtgaaaaa
    20941 tatggtggca atacaggtaa tgtcattgcc tatataaaag gtgaagaagg aagtagacca
    21001 ctttgtttat gtgcacacat ggaccaagtt caaccttgtt taggtgtaaa accaatacta
    21061 gatggtaatg tagttagaag tgatggaact actacacttg gtgcagatga taaagctgga
    21121 atagctgcta tacttgaagc tttagaacat gttattacag aaaaaatacc acatagagat
    21181 atttatcttt gttttacaat ctgtgaggaa gctggtatgc atggtgtcaa aaactttaat
    21241 cctgacaact tgccttgtaa agatatggtg attttagatt ctggtggagc tattggttcg
    21301 atagcataca aagctcctgc tcaacaatct ataaaaatct cttttcatgg aaagaaagca
    21361 catgctggta tagaacctga aaaagggtta aatgctatat tagtagcctc tcatgcaata
    21421 agcaacatgc acataggcag aatagattca ttgactactt caaatatagg taaaatagaa
    21481 ggtggtggag ctacaaacat agtaactgat aaggttacat tgactgctga aattaggtct
    21541 catatacctg aaactttaga gtatgagctt aatcatatgg aaaaatgttg taaggatgct
    21601 gcatctaaat ttaatactac ttatactttt gaacataata tgtcttaccc tagttttgaa
    21661 cttagtagag atagtcacgt tttcaagtta agtgaagaag caataagaca agttggtatt
    21721 gttccaaatc caatggtaat tggtggtgga agtgacgcaa atatattagc taatcttgga
    21781 tataattgtg ctatattaag tctaggtatg tatgatgtac acacagttaa tgaatatgta
    21841 aatatagacg aattatatga tactgccaaa atagtttatc atatgattaa attataaata
    21901 tcataataga actctttaaa ttataaaaat aaaaacctat gtatcttcaa ctttataagt
    21961 tatatattag agttgtttta cataggtttt agtattttat ataataattt gttttaacat
    22021 ttttcataat aagctttgat attttatata gtaatttgtt ctaacatttt tcataataag
    22081 cttcaatatt ttgcataata atttattcta gcatttttaa taataggctc tagtatttta
    22141 tattaataat ttattctagt attttacata attatttgtt ctaatttttt tcataataag
    22201 ctttaatact ttatatagta atttgttgta gaattttata caatataatg atttatacag
    22261 ttttataaaa tatcttaaaa cagtatttca gtaatatttt ttggtcttcc tccaccaata
    22321 ctagtctctt ttgcacatat tcgacctaaa cctgcattta ctattttatt taatatacgt
    22381 cttgcacttc tttcacttac atttagatac tctgctaact cttttgaatc ataaatctta
    22441 ctttttctat tctcatttat agcaataatt tttgcaactg actcacaact cattccagtc
    22501 tttttagata tttcgattac cttttcatca gatagcatca aagaataatt taattcattt
    22561 tcggaagcta aaggtcctct tatgttttca tcttcatcta ccaaatatat accaatttct
    22621 tttgaatcta tggagtgtct taatgcttta tgtgcattat tttcagcctg atacgcagtt
    22681 actccagtac caattcctat actaagagaa aagcccatgt cttttatctc tctctttaga
    22741 ttgaatagct tatcataatt atactcatta tcagctaccc ctttatgaac aaatacaaca
    22801 taatcatttc ttccaagtaa aaataaggaa ccttgaatgc ttcttacata gtttactaca
    22861 agcttatcca tatctgattt ttttatcatg tcagaataat agttatctat cttctcttta
    22921 taatctatta aactcaatat ttcaacagca atttgagaaa atcttgcctt acttagagca
    22981 tattcactct ttaccttgtc ataactttct ttgattaatt gtatagtagc ttgtaaacga
    23041 aatacaggat agcctctttc ttttaattca ttatatactg caccaaaacc agttaacatt
    23101 atatccgtct tattttcttc aaataatttt atatgccatt ctacaagttc agactctcct
    23161 acttccaaag aaaatggatt acaaaataca ctcgttgctt taatatcaaa ttctttaagt
    23221 gcatcttcca caacatatct atcaactaca tctatactga atttatctaa ttttatattt
    23281 gcacttttta ttgcccaaaa tgccttcatt atactcgtcc cacttctcgg tacaaatgaa
    23341 tgtggcttac ttatctcata cttagatttt ataaattcat aaactgcaca tcctgtaaat
    23401 ataatagcat cacattcgtc ttcacattta gaaataactt ctattgtatc tactactttt
    23461 tctcttacat atattttagt ctttaaatca ctgtctatct gttttaaatc atcctttatc
    23521 ttaaacccag agtctgaagg acctataata cccactatca taaacttcgc tcctaatcca
    23581 taaatattat actttttaaa aattatatcc tcactatttt ctacttctat ttaattattt
    23641 tgaactactc catcctatct gcatttagaa tggaataatt agcttatttt tgataaagta
    23701 acttctcaaa atcagcactt ggaataggct tacaataata ataaccttga attaccacac
    23761 aatctaaact cactaaaaat tcagcttgtt cttttgtctc tacaccttct gccactacat
    23821 ccatatctaa atcttttgcc atggctatag tgtgctttaa aactattttt tctctgtctg
    23881 tgattccttc ctcattaaag aaaccacaat ctatctttaa tgtatcaata ttaatatttt
    23941 ttaacatatt taatgaagaa tatgctgaac caaagtcatc catatttaaa acaataccat
    24001 ccattctaag gtcggctatt atcttagtaa ataattttat atttttaata aataaacttt
    24061 ctgtaagctc taattctaaa aaagattttg gtatactata tttatttatt aaacttaaaa
    24121 caatttcttt aaaatgtgga ttatgcaaat gtaatcttga tacatttaca gagataggaa
    24181 ctggctcttc acctaaatct atccattttc taatcaaaga acatacttgt tcccatacat
    24241 acatatctaa tctgataata aacccattct tctcaaatag tgaaataaat ttaattggag
    24301 gtattatacc tttttctgga tgaacccatc taaccaatgc ttctgcacca acaattttat
    24361 ttgcattaag attatactta ggttgtaaat atacatggaa ttgcccattt tcaagtgcgt
    24421 attccatttc cctttccatc tgtttttctt caagtgcatc atttcttata gtatcatcat
    24481 aaaatatata gttattgata ctttgtttct ttactttttt gtgagcatat cctgccattt
    24541 cacacgcatt tgtaattgga atatgattat ccaaaattct ataaacccca aaacatggta
    24601 ctaacatata ttcaaatttt tttctattta agctattttt aatcttataa attaccttat
    24661 gaatatctct atcagagtaa ctctcataaa aaatgcaaaa tacatctgca tacatacgac
    24721 aacatatacc attagaacca atgttttttt gaatcaactc tgcaacatat attaaagctt
    24781 tatctcctcc tctaactcca taaatgtcat taattacctt gaacttatct atatccatca
    24841 ttataattgc ataacgcttg tcaggatatc ttttaagcat taaacttatt tgttcacaaa
    24901 aactttcata attgtatagt cctgttaatg tatctttttg gtttttatgt agttgcataa
    24961 gataatctat attttttata gcaactaaaa tatgtgtttg tttctcacct aacttatttt
    25021 tactactaat ctttaacata taaattaatg cccaatagta ctttttatct attcctaaac
    25081 gtctatactc aaaatttagt tctaaatcgt cttgcttgct attattaaga ctatcaagag
    25141 attttagaag gtggttatca ttaaataata ttatatcatc aggatgaatt aaatattttt
    25201 ttatgtatga aaaagttttt tcaagatttt cctttatagg aaaactaaaa atattgctct
    25261 ctgattgata aattggagta attaaattcg tatcaatgca aatagataaa attatatcat
    25321 atgtattata agctaatttt tcataagctt tagaataccc ttttatcatt aaatcatcaa
    25381 aataaacctt atcaactaac tctttatgtt taaataaaat attattcgtc gaatcagcta
    25441 agtcactaat tactttcatt tcattatttc taagtttgtt cttattataa tacctcttct
    25501 tatcttggta cattctctca tcagcaactt taattagctt atgtatatca atattatcgt
    25561 cactccaaat actgcccact gctacactat atatcatctc atccttaaat tcttcactta
    25621 accaactcac taattcttca aatagttgtt ttgatatatc ttcacataat acaacaaact
    25681 catctcctcc aatacggtaa acattataag aatgaaagta tttttttatt attacacatg
    25741 ctgacacaat agcagaatcg ccattagcat gtccaaagtt atcattaata tcttttaacc
    25801 catttatatc tacaaataca actcctatgg atttaacttt tcctttttga aaattatcta
    25861 tatacttaat atatttattt ctattatatg caccagtcaa gaagtcatag tagctcatat
    25921 aatttaattt attttctact tttctttttt tcatctcagt taataaaaaa taagataggg
    25981 atgtcaaaag agaggtatct ccaacagctt tatgtggatt atcaactcca ataaacccta
    26041 ctactttatc atcttgtttt agtgaagatg tcattaaact ttcaattttt tgaggtttta
    26101 aaatttcata ttctattggc tgttcttctt ttatattttc tatatcatca attattacaa
    26161 aacctttttg ttcgaataat aaaaaccaat tctttaattc attaatatca agatttgtta
    26221 gtgcctgttt ttgttcatca acaccttcat tgcaccattc atatgtatta gttacttttg
    26281 ttctatcttc tgatacttca aaaacatatg ctctatcagc tttatgaaat ttaccaatat
    26341 tggttaatac aagatttaca gcatcagaaa aattagattc tgttataaga tgtttaatac
    26401 atccaactaa taactccttt atctctaatt tttctgctat tgacttactt atatcttcct
    26461 tttctgtaat atcaagagct atttctaatc gtgcatgttt gccctcccat ttaattaact
    26521 tgtcctttaa tataaaatgt ctatttgttc gagtattcgt attttcccat atgtaatatt
    26581 catcttcttt taaaatagag tttgtacaaa attcgcaggg agaatctttc ccctgtaatg
    26641 ctttataaca ttttaaatgg gatatatcat taagtcccat tgcctttttc ccaatttcat
    26701 taatatataa aagttcatat gtatctaaag aagaaacata tacaatttca tccaactcat
    26761 ctattaaatt tattacatcc atttatatat atctcctttt attcattttc cagattgaat
    26821 ttttaaagct tttaaaattt tgctatatat ttggcaatga tattatactt ctttatgttt
    26881 taaaatagta ccttaatgag gttctatttt ttagtaaata gaattattat tgtgtcaatc
    26941 gtacaataga gttttgtaat acttaattta atatatttat aattaactat cttattatgt
    27001 atttacaatt aattctcata taaatgacaa atctccacct caattaagta ttccaatcat
    27061 atatgaggat aatacttcat tcatttaaaa atataaaact attatatatt aaaatttctt
    27121 caataataaa ttatttagat tgttactttg atatattata taatatcaca aaggctgata
    27181 taaaaagaca aaaagggcaa tttttttata tcaaaaaaaa tgttaaattg atattatcca
    27241 tatagatgct atatttaaca attctactta cttcccttac acttattagc atatagttat
    27301 taagagtttg ttgcaaaaca acacttagca cactttaaaa agtgtggtct aataagtaat
    27361 caacgaagaa gacataataa agcataaaat atgatatact tttccacgtc atcaaaactg
    27421 aggattttat tattaatata tgataaaata tgcttaataa attaaatttt aatgggagaa
    27481 tagttatgaa aatatttagt ttcttgttgt ttgtagtggg aatatgtttt tgtattgctg
    27541 gatttatggg gcattcctca gctttttctg gtgcaacatt gagttttttt gcaactacaa
    27601 tgatagctgt aagacaagtc aaaactaaga aaaaatgaaa taggcaaatc ctaactttac
    27661 aagttaatat tacataagta attagtctaa aattagatac tttttctatt acagaaatac
    27721 atcatccact ttgtattctc ttaaaaaaat aaaatagcta tgtaaattca agattagata
    27781 gactaactct ctatccattt cattgtaaaa tatacatagc tatttgtatt cgatttaaaa
    27841 tacttagatt ttcttacata acaaataatt tctatctgat tattactcat attcatttag
    27901 taatcactca gcaactaatc atttagtatc tattcatccg ccatacggta acctacccca
    27961 acctcagtca aaatatattc tggctgagca ggattctttt caattttcct tcttatactt
    28021 gccataaaaa ctctaagcga ctgattctca ctttcatagt aatttcccca aactttatct
    28081 attataaact tatgggttaa gactcttcct gaatacttag acatcaactc aataatctta
    28141 tattcgattg gagttaaatg tatttcttca ccattaattg acacaatatg attttcataa
    28201 tctatcttta ggtttttaac ttcaaaagac tttggagcat cattatttat attatcctgt
    28261 tgagctttat ttctaagagc cacacgtact ctagccaaaa gctctgttac actaaaaggt
    28321 ttagttaaat aatcgtctgc tcctccatct aaagcttcca ccttatccct ctcatgctct
    28381 ctcgctgaaa caacaattat tttattagtc tttgcacatg ccctaactcg tcctattacc
    28441 tcaatcccat caatatctgg tagtcctaaa tccaaaatta tcaaatctgg gtcaagagaa
    28501 tgtataagtg atatagctgt tcctccatta tctgtctcta cacacctata attttgagtt
    28561 tcaagagata cttttataaa tttacaaatt ggcttatcat cttctacaat tagaactaat
    28621 ggctttattt ccacttgtct ttcccctcct catcatacat aggtatgcta aatctaaatg
    28681 tagctcctcc agaaggatta ttaaaggcga caatttctcc accatgagct tctactatag
    28741 atttacatat ctccaatcca agaccaatac ctcttctttc aagatttcta gacttattct
    28801 tagtataaaa cctattaaaa atattcccga tatcttcatt tggtattcct tttccattat
    28861 ctgcaacttc aaatagtact tgatttgact ctttttttac agttagttct atcttagaat
    28921 ttttaggtgt atgccttata gcattatcaa ttagatttac taacacttgt tctattaata
    28981 atacatccac atgaacgatt attatctcat ctggaatatt tgtttttatg tctctactat
    29041 tggcaaactt tttgactctt aatatagatt cagctattat ttcatcaaca acctctggtc
    29101 gtttttcaat atccaatttt ccttcatcta ttctggtcat actaagtata ttctcaacag
    29161 aatgagttag ccaactcgta tcttcatata tatttttcaa taattctact ctagtttctt
    29221 tatctatcac atcatcattt tcaagtattg ttgaagatga acccaatata cttgtaagtg
    29281 gagttcttaa atcatgagaa attgacctaa gcaagtttcc tcttaatctc tctctctctg
    29341 cctcaagatt tgctttttta tttttctcaa ataaattttc tctatcaatt gccaacgcaa
    29401 cctgtgttga aactgcttct aatagtatct tttcattttc tgtaataata tctatcttaa
    29461 aacacgcaac acctataaca ccaagaacat ttgattcttg accttttata gggaaataat
    29521 atgcactgct gtttttacaa tattttgtcc caattccaac tggattacct gtcctaaaag
    29581 cttcttttat agcttccttt tctaatactg aatggaatat attctcactt ccatcattgt
    29641 tacaaatata aatacttggc ttacctagat tattattctc atctgcaata gtcactatta
    29701 cagttctatt taatatattt actaaattag acccacaaaa ttcaataatt tgatttttat
    29761 tttttgcttt aagcaacgtt ttgttattct catagagcaa tcttatcatt ttttctctct
    29821 tatgagaaag tctcacttct ctttttatcc tagaagttaa agtacttgtt ataattgctg
    29881 ccattagcat aatacaaaag gtcataggat aatcttttct ataagctaaa aaagtatata
    29941 atggatgcgt aaagaaaaaa ttaaatgata gcactcctat tactgaagaa agtattccaa
    30001 aaaaatatcc ataggttata cttgtagcaa atagtacacc taatatgtat actagtataa
    30061 tattagattc attaaaacct accttttcaa aaactactga tattccagta gcaattgtca
    30121 taaccaatat agtttttatg aagtccttaa taattatctt tttactgaga tagccatctt
    30181 catcataatc atactctttt aagtcttcat gttgtagtcg ttcctttttc atttactaca
    30241 attcctcctt attgttactg tttaaattgg ctctatttta tataatacaa ttttatcata
    30301 ataaattcaa tcaatacatt taattaatgt acttaaatta ctaaaaggtg ctgtcttaaa
    30361 atgaaaataa atctctattt caaaacagca cctatatatt taaattacta atttagtttt
    30421 tacatactta aatcaatagt tttattcaat ttcataaatt ataatacttc aattataaaa
    30481 catttctatc caacaagcat aaatataaag tgggcacata tacctgcaca taaaccacct
    30541 atagtatgcg aaagtatcgc tttaccagcc aatggtcttg catctaaagc atccatcata
    30601 cctatgtgtg tacttaaata tccactccaa cacataccca ttgctgtgaa tactgctata
    30661 tcattaggag ttatagcgcc tgattttata aactctggta ctaaagatat tgctgctcca
    30721 acagctccta atgcagttac agggaatgct attgcctctg gtgatgtgaa tccaaataat
    30781 ggttctatta tgaagctaat cttatcacca atagcaggta ataattttat accttcatat
    30841 gcagctcctg tgtaaacagc ttgacctgta gcagggtctg tagatggtcc aaaagttaat
    30901 aacataacta atgtacaaac tactaaaact cctggcatta tagccatacc catttcaaca
    30961 cctaacttac caccttcaag tatagcatcc aatgttcttt ggaatacatt accatctctt
    31021 atttctctaa actcttcaag ttttgcacct ttatcattta tttgcttttc agtatcattt
    31081 ttagggtcat aattataata ctttttagta aaagtcaaca taattctaac actaataata
    31141 ctacctatta ttgccgcaac attacctatt atagctggta gtacatattc tttaccttga
    31201 gctatcataa aagttgttac aataagtccc ataccaaagg ctgttcctaa attacataaa
    31261 gcaggtactt gatacttctt aaaatattgt gtaaatgttt tgtctttagc aaatggtata
    31321 atagctggat tatcagataa atatgttgca actactcctg ctatactagc accaggtaag
    31381 ccccatatag gtctcataag acccttaaat atcttattaa ctaaagatat tactccaaac
    31441 tctgaaagca atgcactaag tgcacctgca agaactgcca tagccattat taaaaatact
    31501 gtgtctaata aaagcgcatg tgctgtactc attattactt taaacatcat tcctgcaccc
    31561 atgatgcttc ctacatatcc aaatcctacc gccaatagta caataaatac gaaggtttcc
    31621 atacttactg ccttgactct tctcttatcc gacagctttt ccatcttgaa atcttccccc
    31681 ttttaatttt aaattaaggt tcctaacatt ggtacaaatt ttttggtaca aactgagttc
    31741 taaaacttac actcgtaatg caagttgtca gttttttgaa ataaaaaaaa attacgttta
    31801 tagaataaga atatcctctt taatttggat actcttattc tattttatgt tattatatta
    31861 tcatcctttt gtttaaaagt caattttttc tatttttgtt gtttaatttt atttatactc
    31921 tttttatatt tttcattttc ttttatcttt gtaagtactc catataagtt gacttttcta
    31981 aatacagtag ttataaatac caatcctaat gcaattgaac ttgcacacga taatgtactc
    32041 accccatatt ctacagcttt tatataatta ttggtcaaaa cagaatacat agtattatat
    32101 attccataac ctggtactaa tattattaaa cagcaaacac ttaatgtagt tgctggagtc
    32161 atataaattc ttgcacataa ctcacagtat atcgcaaaac aaactgtagc tataaaaaaa
    32221 cataagtttt ctgttactcc catatttaaa agaaatttat acgaaaacca agctatactt
    32281 ccacctattc ctgctagtat taagtttttt cctttcatat taaatagcac tccaaagctt
    32341 aaggcagtaa aaaaagctgc tattacttct ataaacaaat gcacttatat cccccctaac
    32401 ttgaagtaca atccaagtac caagaacatt cctactgcta tagatacacc tacaaaaaat
    32461 acttctgcta attttgcaag accagaaatc aactgtccat ctaacaaatc tcttaatgca
    32521 ttagtcaaag caagcccggg aactaagagc attattgctc ctgctattaa atggtctaac
    32581 gtctttatga atccgagctt taaaattaaa attgaacaag aagctataat aactgctcca
    32641 attgcattta caaaaaagtc attaagggaa gatttactta aatacataat aacaaactta
    32701 gtcagaatcc caacagtaaa tgcagctata aattcttcca catttcctcc aaataatatc
    32761 gaaaaagttg ctgctgcaat acctgcaaaa aatattgtta ttaaatccga gtaatagtta
    32821 tcttcactta tttcatctaa aattttctca cataattcaa tatctaaatt atttatactt
    32881 attgctcttg ataatgagtt aacttcatga accaagttta ggtctactct tcttgagctt
    32941 attcttttaa ttgctgaatg taatttccca tctacaaata cagatgccat tacagctgtt
    33001 ggagttgcaa atacatctac gtggtctatt ccaaaagatt gacatattct agctatcgtt
    33061 tcttcaactc tataggtttc tcctccactt tgcaacatag ctttacctgc atttgaggaa
    33121 aagtttaaaa ttctatctat atccacaaaa catatctccc attcttctat agtattattc
    33181 atattttaat acaagatatt atttatttaa actattttaa ataattcata tccaatattt
    33241 acattttatg aaaaaacttg ttttttatgc ttgtcaaaat caaattttaa gcttgtttac
    33301 accataaaat ggctgaatta atatttgaca aacactttca accatttata taaccttcta
    33361 aattgtataa ctttttacta caaataaaat tatatctctt ttaattcttt ctcttgagta
    33421 tttagcttat agtaacttta tatttatata tgtacaatat aaaacattat ttttatgata
    33481 caaaatataa tttgtaaatg tatatatgta ttaactgtgt atatataaat tattcttgac
    33541 cttatcagtt ttttcatata tcttcatcta taccaaccat atattaataa atgatattac
    33601 atagacttaa gtatattaaa aaacttaaat ttagttattt aacaacataa tactctaatt
    33661 taatctataa aaatccatac ttaatataat gcaactctta ttttaacacc atctattaca
    33721 caaaacaaca tattaaaaag taaaatacaa aatatccact ataaacctta ttttaatacc
    33781 gaatatatat tataatatat ttaatgtagc ttaaatatag tttaaacata aagaaaggaa
    33841 acggtatatg ctaagaaaag ataaagttct attatctcta cataaattat gtgaaaatat
    33901 gactttaaaa gaccttcaat cagataaaac aggattcact acaatagaaa ttgctaacca
    33961 ttcatctctt gatagaagta ataccagtaa agaattaaat aacctataca atgaaaaaaa
    34021 agttctgaaa atatctagta agccaatttt atttctacat gctagtatta tagaaaattt
    34081 aattggccgt actttgaaca gtgatgaatt ttctataaat aattgtaatg agctacttaa
    34141 atcaagtaaa aatgactcag aagatatttt ttcaacatta cttggacatg attctagtct
    34201 taaactacct atagaaaaag ctaaatctgc tatactctat cctccaaaag gtcttaatac
    34261 gttactcata ggacctactg gtgttggaaa aagtacattt gccgaaacaa tgtacaaata
    34321 tgctgtagaa agtaaaatct tttcttctga aagcaaattc gtagtattta actgtgctga
    34381 atatgcagaa aatgctaact tattattaag taatttattt ggttatgtca aaggttcttt
    34441 tactggtgct aataaggata aattcggcat agttgcacag gctgatggag gcatattatt
    34501 cttagatgaa atacacagat taccaccaga aggtcaagag atgctttttc ttttgatgga
    34561 caaaggcata tacagacgat taggagaatc tgacattgtg cacaaagcta atgtctttat
    34621 tgtgtgtgcc acaacagaag atatacattc ttctctgctt gggacttttt taagaagaat
    34681 ccctgttaca atcaacctac ctgctttaca ggataggtct ttaaaagaaa gattatctct
    34741 tattaaatac ttctttatta tagaatcaaa atacaccaat gcaactataa aagttcacaa
    34801 agatgtaatt aaatcattac tcctttatga ttgttttggt aatataggtc agcttaaatc
    34861 tgacatacaa cttatgagtg caagagcctt cttaaattac aaaactggac ttaaggataa
    34921 tatagaaata gatttatccc ttgttcctga ttacatctat attggtcttt taaaattgaa
    34981 tgaaaatcgt agtaatctaa ataaattatc agaacttgat tatatgcttt tttatgaatt
    35041 taatggtaat aacttagaag ttgaatatac aaaagaacta tctaaataca atatagatac
    35101 atcaaacaat ggatttaaat actctacaga gattccttat ctggaaaatg atataaggag
    35161 tatgtttata aattacatgg aaaagtactc tacaaaatta ctttcgatat cttcagtaac
    35221 tcattctgat tatacaagta atgagatttt taaagtaatc aatccaaaga tttactatgc
    35281 tgttgaacat tctttaaaag aggctgaaaa aatatcgaga aacaaataca caaaacaaac
    35341 ttatattgct ctttcaatgc atataagtgc acttatagaa aatataaatc aagacacata
    35401 taatcctaag tacaatttat ataatgataa aattttctta gataaagatt taaatatagc
    35461 taaaatagtt ttaagtataa ttgaaaatga cttacaaaca tctttaccta aagatgaagt
    35521 aaaatttata tccatgtttc taaatagcat gtatcttgaa ccaaacaatc aatctgaaag
    35581 tataggagtc ataatacttg ctcatggaaa ttcaacagca agcagtatgt gtgatgtagc
    35641 aaattcattg cttggtacaa accattgtaa tgcaattgac atgcctcttg atgtaaaagt
    35701 aagtaccata cttgataaaa ctatagagtt ggtaaaagaa tgtgacgaag gtaagggtgt
    35761 acttctttta acagatatgg gctctcttat agcttttgga gaacttattt cagaaaaaac
    35821 aaaaatcaaa actcgctcaa ttgaaatggt atctactcca atagttttag aagcagtaag
    35881 aaaaagtaca ctaccagaaa tgactttgga tgaattagct aattccttaa gctctttaaa
    35941 tccatatatt ggacgagcag caatcgattt aacagaaata aactatcctg aaaagtcaag
    36001 agagtatgta ataataacta cttgtataac aggatatggt tcagctatga aagtagcaga
    36061 ctttataaat tcttcactta aaaatattag taaatacaat attaatttag ttcctcataa
    36121 tatagaaagt tttaaaatgt ataagaataa atttagtaat actaaaattc tggcagttgt
    36181 tggaagtgta gattttaatg tagccaacac cccttttata cacatagagg aactactaaa
    36241 tggatatggc ctagatatgc taaacaaaat aatagaaggt acattcaatg ccaatagtat
    36301 tacaaatata aaagaaacaa atctatcata caacagttta ataataaact ttatgaccca
    36361 aaacttagag cttttggact ctgttaaatt gttcaactat gtcaattctt ccttatttac
    36421 aataatagaa ttaatagatg aaaacttaaa gagcaaattt aagctaggat atatactaca
    36481 ttgctctttt atgatagaaa gatgttttaa aaatacaact tttccatata ataacattac
    36541 tgaattaatt agtaaaaatc atgaactata tagtttaata cgtgaagcct ttaagccaac
    36601 agaagcttat tttaatattt tgataccaga cgaagaaatt gcttatataa tagacatgat
    36661 taatgagtat ctaaataaat aaaatttata gcacttattt tgtgcatatt aattaatata
    36721 tgaaatggag gacgagattt tgaaaggaaa aataaaacag ttaacaatac ttgcattaat
    36781 ttttatattt ataactcctg tatttgcatt tgcagatact ccaccagtac caaattcttc
    36841 aagagcagca ctacttatag accaggaaac taaaagaata ttatttgaaa aaaacattga
    36901 tgaaaaaatg ccattagcga gtttaagtaa aatgatgacc tttttattgg caatagaagc
    36961 agttgataaa aatcaagtta aagagactga tatggtgaaa atagacaagt ctacagcttc
    37021 agtaggaggt tctacttgta aacttaaaga tggtgatgaa atatctctag gagagcttat
    37081 gcagggtcta atgctagtat ctggaaatga tgctgctata gccatagcta aacatattgg
    37141 taaaactgaa aagaattttg taaatatgat gaacaagaaa gcagaagaaa taggaatgat
    37201 tgatacgtat tattttaatc caaatgggct tcctatatat actgacccag aacataaaga
    37261 acctcctatt gaaaatatgt caactgctca cgatatagtt acacttggaa agtatatgta
    37321 cgaccattat gaaaatcaag ttacaagaat aaccactatg caagtatata atgatactaa
    37381 aaaggatttt acacattata acacaaatcc tctgcttgtt tcagtacctg gtgttgatgg
    37441 aataaagaca ggatatacag ataatgctgg atattgcctt gcattttcta tgatggtacc
    37501 taaagatgct aaaaacgaaa gaaatcatag attgataggt gttgtacttg gtgatggtaa
    37561 caagaaaaat agaatttctt cttctgctac tttattgaaa tatggtaaag ataatttcca
    37621 ttctaaaaag atagcacata agggtgatat tatagagact ccttgtgttg atggtattga
    37681 tgattttaag ataacagtta aggttgataa agatttgtat ggtgttgttt cagataacga
    37741 gaatatcaat cctaaggtag tgtttaaaaa tatgaattat cctatccata agggagatat
    37801 tgttggtgtt gcaaagtatt ataatgactc tggtaaattt gttggaagtg ttgatgtaaa
    37861 aagtgaaagt aatataggat gtattccttt gaaggataag attaagatta aggttgctaa
    37921 gataaataaa aaacttgaga ttaaaaattc tgtttgtttt aaagcatagt aaagcatatt
    37981 attaaaaggg tatgttaaat ttataaagac tccactttgt ggagtttttt tgttttttac
    38041 aaaaaattaa aatagtggca acaattgagg atgtgaggga gagttgccac tattttgtat
    38101 agggtattat attatgtttt taagctagtt ttactatctt ctatgtttat ataataagcc
    38161 ttgtatatga atttaattga taattaatat gaaaattatg tgaagttttt aattgatgta
    38221 aagtaataga ttctatttag acacttaaaa ttataataaa acatcttaat ttttatattt
    38281 atactaatta attctagtat aaatacttat taaatacctt tattcaaaca ttatttcaga
    38341 tttatactat tcttatatgt taaaaggctg tagaaaaatt attttaaaaa tcctacagcc
    38401 aatactagta tcatcaagaa aatttacatc ttattaaact aatttttatt catatttcat
    38461 tatttatttt aatatattaa ataaacttga tagcccagaa gatatttttc ctattgttga
    38521 tattggatct gacgcat
//
LOCUS       DAMJXI010000035        37452 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.037, whole genome shotgun sequence.
ACCESSION   DAMJXI010000035 DAMJXI010000000
VERSION     DAMJXI010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37452
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.037"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            <1..515
                     /locus_tag="PC465_002239"
     CDS             <1..515
                     /locus_tag="PC465_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2649532.1"
                     /translation="ISNLKKSLNKLAKLQRELSRKTIGSLNRNKARLKVARLQEHIAN
                     QRNDFLQKLSTKLIKENDIICIEDLQVKNMIRNRKLSRSISDVSWSEFIRQLEYKANW
                     HGRQIVKVGKFFASSQICNKCGYKNEEVKDLNIREWIYPSCNETHDRDINASINILKE
                     GLRLITIQNK"
     gene            947..1201
                     /locus_tag="PC465_002240"
     CDS             947..1201
                     /locus_tag="PC465_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649533.1"
                     /translation="MENKDIKLTICIFAFVIGIIVLFCCIGLGQFNMDCIIKQNGGSI
                     ATEQYNIYLEQSISQYRNFGSILVLLGGIGILFDKSVRKY"
     gene            1237..1560
                     /locus_tag="PC465_002241"
     CDS             1237..1560
                     /locus_tag="PC465_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649534.1"
                     /translation="MARDVFSVKMTPLEAQKMVEKNLEADLVSVDIYNLENNKSIIVT
                     IFEKYYARSNSDAGLVVICENTTGKTLVKITSTGSAIGLFQIDWGTGNNLIKRVKKIL
                     IDYII"
     gene            1834..1986
                     /locus_tag="PC465_002242"
     CDS             1834..1986
                     /locus_tag="PC465_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649535.1"
                     /translation="MDNFLFNVLASVTASYIVYLISKLIKKVKSHSTAKSDLKIDINF
                     KYHRKK"
     gene            2180..3064
                     /locus_tag="PC465_002243"
     CDS             2180..3064
                     /locus_tag="PC465_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HDF2649536.1"
                     /translation="MVGAFVLPNYAIILSEMSNLWGNFIMWILVPIITIVLLIIAVSS
                     MQYILVMIAFLLIIYSFIEKKIVMGLVSVLFFTYSIYLCATWEDKSLIADNKVETVKA
                     QRETVEREKEMERRRIQEEVDKERYIEKHGMEISENDLKVKLEALVPQEYKGKKYELK
                     VGKFKRYSMYFDLTVQNEKFSNSEECKKFVKEIANDLKKIKISKAYFKFHSKDDGGIY
                     NSVYIDYFRNIQNNVDNVENLEFNEFELKTEEEEKREQEKIEQEKNSYNNYIQNRVVD
                     PLDRIKKLKELLDSGAIT"
     repeat_region   3370..3855
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=3370..3397
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaa"
     gene            4047..4199
                     /locus_tag="PC465_002244"
     CDS             4047..4199
                     /locus_tag="PC465_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649537.1"
                     /translation="MKNRRKDKRGFSVLLDKEKLDKFDEVLEEKNLTKKEWLEEKIDE
                     ELEQKE"
     gene            4319..5133
                     /locus_tag="PC465_002245"
                     /pseudo
     CDS             4319..5133
                     /locus_tag="PC465_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
     gene            5185..5346
                     /locus_tag="PC465_002246"
     CDS             5185..5346
                     /locus_tag="PC465_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649538.1"
                     /translation="MCENLLDNMYIEKRKEEYRIKLLKIRETDIDIYNKLESIVYKLS
                     EKKLEKNNK"
     gene            complement(5674..6138)
                     /locus_tag="PC465_002247"
     CDS             complement(5674..6138)
                     /locus_tag="PC465_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649539.1"
                     /translation="MDFGEVKSELSDKDLKDNEEALNKYKKYYLKVYKYYSEMDSIKS
                     IQDIEIEQSRLKGQLQKNSNPIFALYISIMAVVFSTTINLTFDLSDITNYFIRMIMTL
                     LFIVLLIFLVNKGILPIAIPYRNNIQFYTTALDVFEDMKNKILRERKYKKRR"
     gene            complement(6274..6591)
                     /locus_tag="PC465_002248"
     CDS             complement(6274..6591)
                     /locus_tag="PC465_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649540.1"
                     /translation="MDFGNINLILIGIIVIIGTTIIYLIKPKTAFCSKKYFNKLESIY
                     GNIDKKKTVKLEVLYRYVTGLEYIAIGLFTRRLDITIIAIILVAIITTALYYLIRKKY
                     ITI"
     gene            complement(6874..7170)
                     /locus_tag="PC465_002249"
     CDS             complement(6874..7170)
                     /locus_tag="PC465_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649541.1"
                     /translation="MYFKTYILKREVNNKQLEITRSFDLDNLICTATEILKDNEIDLI
                     ITDEVNNVVWRNEKSTPPARECLVIAIEVYWWYTSIFLLYHINYVIKKSYLNRF"
     gene            complement(7189..7602)
                     /locus_tag="PC465_002250"
     CDS             complement(7189..7602)
                     /locus_tag="PC465_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649542.1"
                     /translation="MKVKSKRSFIVGIIVCVLCCASLVIYCILKDKRFLISSFLLIVI
                     AIFNFCNAFSRKGIVEELHDSTDERDLYLTMKTSHILVKIMNYTLFTFTFLFIIAYSA
                     WKNQSLLVIAITLCVIEIFLFVAYLLINIFLEKKE"
     gene            complement(7586..7819)
                     /locus_tag="PC465_002251"
     CDS             complement(7586..7819)
                     /locus_tag="PC465_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2649543.1"
                     /translation="MKTKVREFRTNMGLTQQQLADLVHVSNRTIISIEKEQYSPSLML
                     AYRMAQVFGTTIEELCCLKENKEMEDKKHESKE"
     gene            8038..8412
                     /locus_tag="PC465_002252"
     CDS             8038..8412
                     /locus_tag="PC465_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2649544.1"
                     /translation="MKISKLPEAELKVMRYICEANKVLTSRELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNILVKEKKYLRFETKEFLKNIHKNSISSLMSALH
                     GEDDEVDEDKLSELEECFKNLK"
     gene            9024..9716
                     /locus_tag="PC465_002253"
     CDS             9024..9716
                     /locus_tag="PC465_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2649545.1"
                     /translation="MYNILVVDDDKEIVDSIEIYLKSEGFKIYKAYDGMKALEIITEN
                     DIHLILMDIMMPKLDGIKATVKIREERNIPIILISAKSEDTDKIIGLNIGADDYITKP
                     FNLLELIARVKSNLRRYVTLGNYEDTCKEILKSGALELNTLTKEVKIDGENIKMTPIE
                     YKIIELLLENKGRVFSIDEIYEKVWNEESFNSENTVAVHIRRIREKIEINPKEPRFLK
                     VVWGVGYKIEKF"
     gene            9912..11972
                     /locus_tag="PC465_002254"
     CDS             9912..11972
                     /locus_tag="PC465_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2649546.1"
                     /translation="MEKYRVLKLVSLIIISISFPLTILLVTIGLAEPKYNIQKTSTKS
                     GIFDISDDFYDSNIFDEGTMASLLPKFKLSVGGKLTSKEKGKFQQEGKSIDLSSSDSE
                     YDKIMINEQASEEYLSYLKNIKVYVINTYTGVFYTNTSYASLYDFKQKTKSYCNVEII
                     NKIGKSSYIKTINGEKFELNNLSLELNEVDEGFEAYVSFPEEPTIEDGIVYTNFQIFK
                     QATEKVRLFFVASLSLAIICLLSIILYIKIKGEVLKRNNVFLLIYSKIPMEFNVILVS
                     ISIAILTIYALAVSYHIDVIALVSLSLLIVSNNIFFINVQLSYLENKMCIFKTSIIVR
                     VILWLIKTVREVSNAIKKVSLARKVIVIVIISLALIMVISTRSIGMGLLFSICIFLGF
                     TIYITKRLSYLSYVIEGTERIKKGELDYKIKITGNDNFTSLAENINNIGEGLDRAIEE
                     QVKSERMKSDLITNVSHDLKTPLTSIINYVDLIKKEESIQPEYINDYINVLESKSKRL
                     KLLIEDLFEASRVSSGNIELQISKIDLVQLLRQSIGELEEKLSKNNLYLKLNVPNDKV
                     YIWADGRRMYRVFENLLSNIAKYSLEETRVYIDVYDYGENVKVTMKNISSYELNFDPS
                     EIMERFKRADESRNTEGSGLGLAIARDLVALQGGKFYIEIDGDLFKANLEFQKYEEEI
                     TNME"
     gene            complement(12178..12501)
                     /locus_tag="PC465_002255"
     CDS             complement(12178..12501)
                     /locus_tag="PC465_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HDF2649547.1"
                     /translation="MNNNYIFFIIIGMYIVTYLPRVLPMLIFSKKEMPDFLKKIMKFI
                     PVAILTSLTAKDVFFNGDSLYLSIANPKIISFMIVLLVAYKFKSIGISIITGVISIYL
                     FGIIL"
     gene            complement(12494..13195)
                     /locus_tag="PC465_002256"
     CDS             complement(12494..13195)
                     /locus_tag="PC465_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HDF2649548.1"
                     /translation="MERTQQLKESFIASIPIFLGYIPIGIVGGILLQKSGLSPFQIAL
                     MVTLVFGGSSQFIAASMISTGASVTSIVLTTFIVNLRHFLMSSNLNMYIKNKSPKFIL
                     PFCHTITDETFAVNYEKFTAGNWSDRNAIYLNFFCLISSVLANFIGAFLGESISIDSS
                     ISGFILTSMFIALIVSQIKNKIYIVVFISSIIISVILYALFKSNLVIIVASILASLIG
                     FFIEESYCKKEESYE"
     gene            complement(13473..14858)
                     /locus_tag="PC465_002257"
     CDS             complement(13473..14858)
                     /locus_tag="PC465_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2649549.1"
                     /translation="MPINSFENYPMNWKPKRPSKGQILYKALAEQLEQDINNGFLLPG
                     TKLPPQRELADFLDVNVSTISRAFKICEKKGLISGVTGSGTFVSYDTRSNLFLMSSNN
                     KITFIEMGTMNPDFTLEEMNTLFKHIIKEIDFKTIFQYGQRDGAKWQKEAIAKLIYKA
                     GLETTSDSLLPASGGQNAIVAILAGLFQHGDRIGVDPLTYPGIKTAAKMLGIQLIPIK
                     QEDNEISEEGLLYACKNENIKGLYIIPDYQNPTTHIMSQNGRKMIANIASKYNLIVIE
                     DAIHSLLNETHLNPVASYLPNQTIYITSLSKIIAPSLRLAYISTPKQYREALSSALYN
                     INLSQSYFLTEIAYRMITSGEADKLINARRKSARRRNKIINQYLSGYNLLGNEECIFR
                     WLILPDGIMAEKFEIQALKEGVQVYASERFAVGKEKPISAIRIAVCATESTEELKAGL
                     SVLKRLLEEKK"
     gene            complement(15304..15726)
                     /locus_tag="PC465_002258"
     CDS             complement(15304..15726)
                     /locus_tag="PC465_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HDF2649550.1"
                     /translation="MNTFKTEVLLKYSAKDIFNIFTKSARLNFPNFNEKKAVGTFVQQ
                     KNNKRFKVEITNFEKNRVYEIKTSNKRESTITRYELVHIDLENTKLIFIESESKRNIF
                     GKINSALVRVLFGKRQPEEFNKFIKKLEMELENNSVNL"
     gene            16204..19107
                     /locus_tag="PC465_002259"
     CDS             16204..19107
                     /locus_tag="PC465_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2649551.1"
                     /translation="MELRDKLVNIINTENKKDPLTDVQIAKFLSTTRENITNLRKELN
                     ISNSRQRRYPYLKSAISAILQKNKNISISEITRELMTEGFNISRRVVEELLPKESLEM
                     DVVEESEEESNDPFETLIGNKGSLRNAVEQAKSAILYPPKGLPTLIIGESGVGKSLFS
                     RHMYEFAKQKKIVKESSNFVVFNCADYSDNPQLLLSLLFGYKKGTFTGAEYDTPGLVE
                     EADEGVLFLDEIHRLPPKGQEILFSILDRGKFRRLGETNAERKVSIMLIGATTENVET
                     NLLLTFRRRIPMLITLPPLHDRLLKEKIDLIYNIFQQECNRINAKIFVDKNVIEILAL
                     KKFSGNIGQLQNMIQVLCARAFMKFINSKDEDSESIVVVDINEVLKLKDSFKDAAFQE
                     IEYTEIRKYLKNAIFIPFNLEESSVKGSLLSDEYILPEDIYKTIEKKYYDLKSLDIED
                     IDIENILWTFILNRFADLKFNLDSNEEIFSMSDLNSFVSDSLVKLVKELMNDIVEKNM
                     NLEVNKNMFKYLAIHLEEAIKRIKLNQKIINVNLEKIKIDFSKEYEISKSFAIKIEES
                     IGIKIPDDEIGFITLYIKSALKNEVKKDKVGLIIISHGRIATETVNVVKELLGVKFPV
                     AIDMPLDEKPINIYNKAVELSKIIDQGKGILFLVDIGSLTNIGQIVNKRTNISTKTID
                     RVDLLMALEATRKVSMGEEELDEIFFSLLKDRMGYNYELEKHIDKSNAIITLCLTGEG
                     TAKYISKTLEEKYDNTKCYQMSALDENLFCKIENLKETNNILAIVGTINPKIPGINFI
                     PYNKELFKNLDIYLSKSKQQDDRPIKSYERMLDEDLVIFEPDIYFKKDLLEYVCSILI
                     NKEYVEKDYLDSVLHREEMLPTYSKGAIGVPHGDSSTVNSTRFVFVKLKNPIDWGVGN
                     VNFIFMPVFQANDKEIVKNVLEILKDAEFMNNANKCFDKDAFRRIIFDKFKHL"
     gene            19140..19586
                     /locus_tag="PC465_002260"
     CDS             19140..19586
                     /locus_tag="PC465_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2649552.1"
                     /translation="MNVDLISLGLESNDYESVIEELGSIMCKKEYVKETYINAVLERE
                     RTLPTGLDIGEMCVAIPHTDSKHVNESNVAVGILKNPVKFNSMIDPKDRLDVELVFLL
                     AVKNPDSQVKLLKDLMSVFQNIKLLKNIKNASTKEEVAKLLDFIEI"
     gene            19709..20011
                     /locus_tag="PC465_002261"
     CDS             19709..20011
                     /locus_tag="PC465_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2649553.1"
                     /translation="MKQFNVLSVCGSGTVTSSMVAGKLKEVLGNKGISITTTEARPTE
                     ALNLAQSGRFDFITFTSPLQTGDYGIPTINAFACLTGIGEEAFFEEVLTVIEGIDK"
     gene            20192..21598
                     /locus_tag="PC465_002262"
     CDS             20192..21598
                     /locus_tag="PC465_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDF2649554.1"
                     /translation="MLEFMKSIIDTFGSAIIVPIIIFIIAKIFKVTTKKSFLSAVYAG
                     VALQGFTLILNSFTPIITPVINRMVESTGVNLPVFDVGWQATSLVAFSTSAGMIYLGL
                     GILLQTILFLIKWTDVFQPSDLWNNYSYMVWGAMVIGVTGNFPLGIACMVLLNLYSLL
                     ISELVAKRWSSYYRYPNCTIIAMHNVEASVFAVFADPIYNKLGLNKIKLNPKELEKKL
                     GFLGEPITLGLFLGMFIGILGNMTRINTMEAWGEIMKVGISTSAVMAIFPKVASMFAQ
                     AFAPITEAARKIMQKAGNREWYIAVNDAVGYGEPATLISGLILIPIMLVIAMVLPGNK
                     VLPVVDLLAIPYMVQGLVAIHNGNIPKVLVSGIIWFGLGLYVCTSTAPLFTDMATNIG
                     VAIPAGAMLITSFNILGKPLMGLVFFAFLSANPIYIGLSVVIYFVLWALFRKNKTSIL
                     DYLEKQALKNVEEEPVAV"
     gene            21942..23000
                     /locus_tag="PC465_002263"
     CDS             21942..23000
                     /locus_tag="PC465_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF2649555.1"
                     /translation="MGDKMRASVLYNVGDVRYEMVDIPEITDTQVLVNVKYVGICGSD
                     LPRSMVSGLSGNTKYPLILGHEFSGEVVKIGEKVKHINVGDRVAVAPLVPCGKCDYCN
                     EGNFGLCDDYNIIGTRVNGAFAEYVRVPEEHILKLPDTLDYETAAGIEPATIAYHGIS
                     KSNIRVGDSVVVLGCGPIGQFVIQWAKVFGASKIIAVDIFDEKLELSKLLGANYILNS
                     KEVNVIKEIKKITNGGADVVIETAGSRFTQEQSLFVAKKRGNIVFVGISHTELPLSAD
                     ATECILRGELTLKGSWNSYTSPYPGRAWTATLDFMEKGDIIFKPMISDKIGLNEVGDF
                     LSKMSKREINFNKILVEM"
     gene            23099..23785
                     /gene="araD"
                     /locus_tag="PC465_002264"
     CDS             23099..23785
                     /gene="araD"
                     /locus_tag="PC465_002264"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDF2649556.1"
                     /translation="MLENLKEEVLKANLELPKKKLITYTWGNVSGIDREKGLVVIKPS
                     GVEYSNMTVEDMVVVDLEGNIVDGKLRPSSDTPTHLVLYKEFEELGGIVHTHSSWATI
                     WAQIGKSIPSCGTTHADYFYGSIPCTRKMTREEICNEYEKETGNVIIEEFMGRNPIHC
                     PGIIVNDHGPFTWGKDANEAVHNAVVLEEVAKMAYYTELMSPDNIMDKVLMNKHFSRK
                     HGKNAYYGQK"
     gene            23803..24450
                     /locus_tag="PC465_002265"
     CDS             23803..24450
                     /locus_tag="PC465_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HDF2649557.1"
                     /translation="MLDSLKGKVVEIAIKAEHYGLCKEKTGNFSIRDKDTGYILITPS
                     GVGREELKVEHICVLDLDGNVIEVEKGIKPSSEVLMHIEIYKTRENINAISHTHSLYA
                     TAFSVAKKPIIPIVYESVNYGGYVDIASYERPGTLKLAKSVSKLLIDTDACLLERHGL
                     TTVGNDLDEALLKSRYVEEVAEIYYRSLVLNQFKELEVVDVDEFKSWKYPEEIKF"
     gene            complement(24623..25990)
                     /locus_tag="PC465_002266"
     CDS             complement(24623..25990)
                     /locus_tag="PC465_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HDF2649558.1"
                     /translation="MNLIDILNKVDAFIWGPPLLVLLVGTGILLTVKLGVVQITKLPR
                     ALKLIFSAENKGSGDVSSFAALCTALAATVGTGNIVGVATAIKAGGPGALFWMWIAAF
                     FGMATKYSEGVLAIKYRTKDKNGQVSGGPMYYIVNGMGEKWRPLAIFFAISGILVALL
                     GIGTFTQVNSITDAINNSFGIDPRITGVVLAVFVALVVFGGLKSISNVATKIVPFMAV
                     IYVVICGIILISFWNKIPETFMLIIKSAFTPTAATGGFLGATMSLAIRNGIARGVFSN
                     ESGLGSAPIAAAAAKTEWPAEQGLISMTGTFIDTIIICTLTGFSLVISGVWCSDLNGA
                     VMTQAAFNGAIPTFGPILLTISLTLFAFTTILGWSYYGERCFEFLFGVKGMNGYRTVF
                     VAMVLLGAFLKLEVVWIIADIVNGLMAIPNLIALLALSPIIVSETKKYFEHINSPENQ
                     IKKNA"
     regulatory      complement(26180..26268)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            26696..28816
                     /locus_tag="PC465_002267"
     CDS             26696..28816
                     /locus_tag="PC465_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDF2649559.1"
                     /translation="MGKILVLAEKPSVGRDIAKVLGSKNEKNGYIEGPKYVITWALGH
                     LVTLADPESYGERYKSWSLEDLPILPKHLKTVVIKKSGKQFNTVKSQMNRNDIDEIVI
                     ATDAGREGELVARWIIEKSQVKKPIKRLWISSSTDKAIKDGFAKLKSGKEYENLYYSA
                     IARAEADWIIGINATRALTTKYNAQLSCGRVQTPTLAMLLKREEEIRNFKPKEYYGLE
                     LIATKGNSDIKFIWNDKNNNSSTFSKEKIESTLKKVKGVDIKISEVNKSYKKKYSPAL
                     YDLTELQRDANKMFGFSAKETLSIMQKLYEHHKVLTYPRTDSRYLTSDIVGTLKDRIK
                     AVNISDYSKICNRLLKSNIIANKSFVDNSKVTDHHAIIPTEQKVFMSDFSDKERKIYN
                     LVVKRFLAVLSPPFEYEQTTISATVEGEIFKAKGNKVINLGWKESYKDIEDEDEYESI
                     PNVLEKDVLKVKGLKITSGKTNPPPYLNEGTLLTAMEKNGLGTVATRADIIEKLFNSF
                     LMEKKNKDIYITSKGRQLLDLVPVDLKTPELTASWEKKLLDISKGKLSKNTFINDMKD
                     YSKDIVLEVKNSDNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICEDRECNTRKTIS
                     QVTNSRCPNCHKKLELRGEGEGRIFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYL
                     KNQNKNQETFNNPFAEALAKLKNK"
     gene            28920..30173
                     /locus_tag="PC465_002268"
     CDS             28920..30173
                     /locus_tag="PC465_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HDF2649560.1"
                     /translation="MDLSGIFKYYCKECENTWNNSSVELFENIETYSKDSQKKREKEL
                     DKLLNTISVHLERYPSDAVLRKMWVKKGEVFLQKTLEKENIFKLEKMDVEDRKKFLDI
                     TKQFIRDARKFDDDLPIGDIMQAMRNVWISNALQLLFGKEVYYSKANFAYSMLYPYTD
                     NYLDNTNIDKNDKILFNNWLEKRLLGEHIKSKDYHESKVSQMIDYIESVYPREKFTEV
                     YESLLLIFKSQVNSLKQHGKENHLCKEDLLSISIEKGGSSVLVDGYLISGLMTKEEIE
                     FCIGYGFLLQISDDLQDIKEDLKYNHKTIITEMSKEGTLDKVVNKLINFTIELIDSFK
                     INNKNKSVITMIKNDCLMLILFSVVYNAEFFSVGYIKEVEKFIPYTIDYSLEIEEKIK
                     EKFKNIDVLNNENEYKEMIDIICAE"
     gene            complement(30327..31388)
                     /gene="ytvI"
                     /locus_tag="PC465_002269"
     CDS             complement(30327..31388)
                     /gene="ytvI"
                     /locus_tag="PC465_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HDF2649561.1"
                     /translation="MDIQKQKNFIIKFTYVVLITSIVYIVLKFLLPLLMPFVISFIIA
                     SILRPIIRLITNNTNLNRTLISIVILLIFYGLCIFLLVSFGVKIFASVSDVFFRLPEI
                     YKSSIQPTLNTLFSKIDASTPNVNLALILGWDNISQSMMSLVASISTNALNAIASIAS
                     KTPAFMLKLIITLIASFFFTFDYQKIVNFILKQFPEKSQFMIINIKNSSINALLKLLK
                     AYAILLSVTFIELLIGLTILKVENAFTISVIIALVDILPVLGTGSILTPWMIISLING
                     NINLAIGLLILYIIITVVRQILEPKVVGHQIGLYPLITLMCMFVGAQLFGIAGLFGFP
                     IAATIIKNLHDNGIITAFK"
     gene            31662..32402
                     /locus_tag="PC465_002270"
     CDS             31662..32402
                     /locus_tag="PC465_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HDF2649562.1"
                     /translation="MKNFRDLGGNKTEDGRTVKKGLFYRSAKLSNLSENDIKILKELN
                     IKYIFDYRSDEEARKHPSTIISNIKNIRIPAMRELEESGGSFGSIEDMIDGLFEKDGA
                     FNMLNNSYYNLPINNPSYKKLVELIRDYSNLPILNHCTAGKDRTGVGSAIILMILGVS
                     RENIMKDYLKSNDFADKEIERFIEYKPKFKDIPKENLKYIFGVNEEYMKTAFRRIDEE
                     YISVEAYLYGEFNLNKEEIRKLRNQYLE"
     gene            32414..34192
                     /locus_tag="PC465_002271"
     CDS             32414..34192
                     /locus_tag="PC465_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2649563.1"
                     /translation="MSLNITARQINIIKILLNSKDTISGIALSQEIGCSSKTIQNEIK
                     DINKQLRNGKILSIRGVGYKLEGSFDEVNLNSNLYDDVDRVEYIIRKILTLSNEEKNT
                     IKLEDLADSMYVSVSTVKNDLKEVKRILEKYSISVKSKHKQGICVLESEDKILNCIVD
                     LSNKRDNQLSLNDFLNDDIKERKLLIKKLLLDILNENGLVLTDIEFKSVLNNILVMLS
                     RHKYNEKEFIENYIENYRSKRSSILENEQNKEIIINSIKTFCKNLKLATSIDISNDKV
                     FEEFLYKHISSLCKKIKLGINQSPIMAQDIKIKYPFAFELANIAKKTIEKDLKIEINE
                     DEVANIALHIGGAVERASYNNKDKVFKTIIVCTSGIGTSMLIKAKLENIFKEKLEILK
                     IIPSYLVEYIKVIDVDFVISTVPIEVGDVPVINISPILSEKEIRLIEKYIETGNIYLD
                     LDIKSLFDSELFFTDLVFKRKEEVIDFMASKLVQKGYIDEDMKKSYFEREKIATTEIG
                     NMVTIPHGAIGKIFDNKIAIGILKKPISWEISDVRLIIMLALDKDKILDYEVIFSKIY
                     KRVDSIAKVISICENSSFEKFVNLFN"
     gene            34359..35276
                     /gene="pfkB"
                     /locus_tag="PC465_002272"
     CDS             34359..35276
                     /gene="pfkB"
                     /locus_tag="PC465_002272"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDF2649564.1"
                     /translation="MIYTVTLNPSIDYIVKLDELKTGSTNRVKEEYVYPGGKGINVSR
                     ILKELGNDNTSLGFISGFTGEYIIRTLEEKELKTDFIKIKSGFSRINVKIKALKETEI
                     NGQGPNIDDEDIDTLYKKLDKLNQDDILILAGSIPSTLDEKLYENIMARLEKKNIKVV
                     VDATKNLLLNVLKYKPFLIKPNNDELEELFGVKLNSIEDMVKYARRLKEMGAINVLVS
                     MGKGGALLITEEEEVLISDVPKGKVKNSVGAGDSMVAGFISGYLNTGKYDYALKLGAA
                     SGSATAFSYDLAKREYIDKLVNEISVKKF"
     gene            35313..37232
                     /locus_tag="PC465_002273"
     CDS             35313..37232
                     /locus_tag="PC465_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2649565.1"
                     /translation="MKIIDLLDEKSIKLNLNSKTKSEAIEELVDLVANSGNLNDKENY
                     KKAILAREEMSTTGIGEGVAIPHAKNSSVTKACIAAAVSKEGIDYESFDGSLSNLFFM
                     IAAPDGANNTHLEVLSRLSTILMDEDFRNKLINSSSEKEFKEIIDKKEREKFSEEYQD
                     EKVTEKNIIDTKENDANKYPKVLAVTACPTGIAHTFMAAESLNKMAENKGVSIKVETN
                     GSAGVKNKLTKDEIENATCIIVAADKNVEMARFNGKKVIKTKVADGIHKAEELIDKAV
                     NGDAPIYHGGDGSHNESNEESESGFRKVYKHLMNGVSNMLPFVIGGGILIAIAFLLDD
                     YTINPSNFGSNTPIAAFFKGIGDKAFGFMLPVLAGYIAYSISDRPAFVVGFVGGALAG
                     DGGSGFLGALLAGFIAGYLVEGLKKIFSVLPASLEGIKPVLLYPLLGTLLMGIIMTFL
                     VIPPVTAINNAMVGFLNGLGGTSKIFLGLVLGGMMAVDMGGPVNKAAYVFGVASLESG
                     QFEIMAAVMAGGMVPPLAIALATTFFKNRFTKEERDSGKVNYVMGLSFVTEGAIPFAA
                     GDPLHVIPACVGGSAVAGALSMLFNAALRAPHGGVFVIPVVTHPFAYILAIAVGALVG
                     MMLLALLKKPLNQEV"
BASE COUNT        14952 a         4047 c         6160 g        12293 t
ORIGIN      
        1 ttatctcaaa tcttaagaag tcattaaaca aacttgctaa attacaaaga gaattatcaa
       61 gaaaaacaat cggtagttta aatagaaata aagcaagatt aaaagttgca agacttcaag
      121 aacatatagc taatcaaaga aatgattttc tacaaaaact atctactaaa ttaataaaag
      181 agaacgatat tatttgcata gaagatttac aagtaaagaa tatgattagg aatcgtaaac
      241 tatctcgctc aatttctgat gtgtcatggt cagagtttat tcgtcaatta gaatacaagg
      301 ctaattggca tggtagacaa attgtaaagg tgggtaaatt ctttgcaagt tcacaaatat
      361 gcaataaatg tgggtataaa aacgaggaag tgaaggactt aaatataaga gaatggattt
      421 atcctagttg taatgaaact cacgatagag atataaatgc aagtataaat atattaaaag
      481 aaggattaag actaataaca attcaaaata aataacgtat gtaagaaccg taggaactac
      541 ggggatagcc tgtggagaat tagtaagaca tatgttagta tgcaaaattc tgtgaagcag
      601 gaaacctgtg actttagtca tgggaggttc aggctagtat tactcattat tgtattcaaa
      661 agctaaagtg gaaacctagt gaatatatga atttagaagt taattagaga gcattagcag
      721 ccgactcaat acttattaaa attgaagatg aagaagaaac aatgaaagaa gctgaaagag
      781 agaaaaagag aggtagaaga aggtagaatt taaagttaaa atagttacat tgctaatata
      841 tgaaaatgtt acaaatttgg aaatagatgg atatatatgt tgtatagtat aatgtagata
      901 atatatcacc aagtaaaaaa caacaaataa atctaaatta tgaggggtgg aaaataaaga
      961 tattaaactt acaatatgta tatttgcttt tgtaattgga ataatagtgt tattttgctg
     1021 tataggtcta ggtcaattta atatggattg tattataaaa caaaatggtg ggtcaatagc
     1081 taccgaacaa tacaacatat atttagaaca atctatttca caatatagaa attttggttc
     1141 tatactggtt ttactaggag gaataggaat actgtttgat aaaagtgtca gaaaatacta
     1201 aaaaagtata tttttattta ggatgtgatg aatgatatgg caagagatgt atttagtgta
     1261 aagatgacac cactagaagc acagaaaatg gtagaaaaaa atttggaagc agatttagtt
     1321 tctgttgata tttataacct agaaaataat aagtctataa tagttacaat ctttgaaaaa
     1381 tattatgcaa gaagcaatag tgatgcaggt ttggtagtga tttgtgaaaa tactacagga
     1441 aaaacacttg ttaaaattac ctcaactggt agtgcaattg gactatttca gattgattgg
     1501 ggaacaggta ataatttgat taaaagagta aaaaaaatac ttattgatta tattatttaa
     1561 ttattttatg tagatattct taggttggta tggaatttgt actaacctat taagtaatca
     1621 ataaaactaa ataaacatag aaagcactta caaatatgta ggtgcttttt attgaaaaaa
     1681 tagaaaataa aataaaaagt aagatatagg aaaaatatgt aagaattata tgttataata
     1741 attgtagcaa gaagatgtaa tctacaattt atagagtgga gttcatgtat taaaaaatta
     1801 tcctcccaac gataagaagg gaggtgaata tacatggata attttttatt taatgtgtta
     1861 gctagtgtaa cagctagtta catagtttat ttgattagca agttaatcaa aaaagtaaaa
     1921 agccactcta ccgcaaagag tgacttaaag attgatataa attttaaata tcatcgtaaa
     1981 aaataacttt cagttataga acttcactct accgcaaata gattgtagtt cttcttgttt
     2041 ttattatacc acaaattaga aaaaatattg catataatat tttttatagt caataaaaat
     2101 atgaaatttt ttatacacaa tgatgatgaa tctaactaga tgaataaatt taattgtaaa
     2161 taagaaagta cttacttaaa tggtaggtgc ttttgttttg ccaaattatg ctataatatt
     2221 gagtgagatg agtaatttgt gggggaattt tataatgtgg atattagtac caataataac
     2281 aatagtatta cttataatag ctgtttcttc tatgcaatat attttagtta tgatagcttt
     2341 tttgttgatt atatattctt ttatagaaaa gaaaatagtt atgggtcttg tgtcagttct
     2401 ttttttcact tattcaattt atctttgtgc aacttgggaa gataaatcct tgatagcaga
     2461 taataaagtt gagactgtta aggcacaaag agaaactgta gaaagagaaa aagaaatgga
     2521 aagaagaaga atacaagaag aagtagacaa agaaagatat attgaaaaac atggaatgga
     2581 aatatcagaa aatgatttaa aagttaagct agaggcttta gtacctcaag aatataaggg
     2641 gaagaaatat gaattaaaag taggaaaatt taaaagatat agtatgtatt ttgatttaac
     2701 tgtacaaaat gaaaaattta gtaattctga agaatgtaaa aaatttgtaa aagaaattgc
     2761 taatgatctt aaaaaaatta aaataagcaa ggcgtacttt aagtttcatt caaaagatga
     2821 cggcggtata tataattctg tttatattga ttattttaga aacatacaaa ataatgtaga
     2881 taatgttgaa aatttagaat tcaatgagtt tgaacttaaa accgaagaag aagagaagcg
     2941 agaacaagag aaaatagaac aagaaaaaaa cagttataat aactacattc aaaacagagt
     3001 ggttgaccca ctagatagaa taaagaaact aaaagagttg ctagattcag gagcaattac
     3061 ataggaagaa tataataaaa agaaaaaaga attattagaa tagataatat agtaagcact
     3121 tacaggtatg taggtgcttt taaatttaca aagtattcca ttttaatttt atagtttaga
     3181 ttttatgata taataaaaat atagaagttt tgcagtgtgc gatatttgtt acaaagtagg
     3241 gcttaatact tgaaatctaa gatgttgagg gtgcgtgata agtgttatca attgcactat
     3301 tgccccctca ctgcaatttt aagagtattg tatatatgta ggtattggaa atgctaagtt
     3361 tattttgggg ttttagatta actatatgga atgtaaaaat ttttgacgct atgaagaaat
     3421 ttactacaaa atttgtttta gattaactat atggaatgta aaaacttttt tcatcctccc
     3481 aaacctcttg ttcgctgtcg ttttagatta actatatgga atgtaaaaaa gaaaataagt
     3541 ttaaaaaaag gtttcattat tatatcgttt tagattaact atatggaatg taaaaccaat
     3601 tatgtacagt ttagttactg tgttaagtct tgttttagat taactatatg gaatgtaaaa
     3661 tccttttata aatatcttct gacatgtgta tatgcttgtt ttagattaac tatatggaat
     3721 gtaaatcggc tacaacggta taaattaaat ttagcagggt acattttaga ttaactatat
     3781 ggaatgtaaa ttgctgtgat ttcaataata aaacaattaa taattgtgtt ttagattaac
     3841 tatgtggatt caaaattaaa taaacaaaga aagcacttac aaatatgtag gtgcttttat
     3901 tctgctcaaa attggtcggt tgggtaaaat aattagaaaa agttagtaaa aacctattga
     3961 ctgtaactcg ttacaatatt gttattaatg taacgagtta cagaaaagag gtgaataaaa
     4021 tagcaactaa aagtagggca gagtatatga aaaatcgtcg aaaagataaa agaggtttta
     4081 gtgtactttt agacaaagaa aagttagata aatttgatga agtgttagag gaaaagaatc
     4141 taaccaagaa agaatggcta gaagaaaaaa tcgacgagga actggaacaa aaggaataaa
     4201 aaataagggt cactcccacc gaccaaagtt tgagtaaccc ctatgacgta tactatcgta
     4261 tatcaattat agtatatgtc attccttaaa aaaatcaatt attaaggagt gtaatattat
     4321 gaaaaatgaa ttaatgatgt ttgaaggaaa agagattgaa gtatttgaat ttgaaggaag
     4381 aattttattc aactcaaaag atgtagtaaa ctgtttagac ataaaaaatg ttaatgagaa
     4441 tataagactt atgaatgaaa agcaagttgt aaagttaaga aattcggata tcagtaatac
     4501 tgacatccga aaacttaata atgctggaga aaattttctt actgaaagtg gagtgtataa
     4561 attaatcttt aaatcaagaa aagaagaagc tgagagattc caaggctgga taagtgatga
     4621 agttttacca agcataagac aaactggtgc atacataaat aataatgcaa taccgaaaag
     4681 ttgagagaaa aagcaagtga gattgaaaaa ttacagttgg tttataacag tacatctatg
     4741 ttaaaagaat tgctagatga tgcaggcttt gacaataaat caaaactatt aacagctaaa
     4801 acattatata agaaagcagg aattgattta ccaatagaga taaacgaaga agaacattat
     4861 tttgatacaa aacaaatagc atctaaactg aaaatatatt ctaagagtaa taaaccagct
     4921 cagatggcag tttgtgagat tattaaaaag attgatttag aagatggtga agttaaaggt
     4981 gtttgggaaa ttaatggttc ttggactggt actgtaaata aatatacaaa gagtgtaata
     5041 gataaggtga gaacttggat agaggaaaat aatagaccta ccaagattgc aggtgagaag
     5101 aagaattatt atgtatttta caaaattgag taaatttatc agttgtatta aataatttag
     5161 tttagttttg gggggattaa tacaatgtgt gagaatttac ttgataatat gtatattgaa
     5221 aagagaaaag aagaatatag aattaaactt ttgaaaataa gagaaacaga tatagatata
     5281 tataataagt tagaaagtat agtatataaa ctttctgaga aaaaattaga gaaaaataat
     5341 aaatagacat ataaagcact tggatattct actgtttcaa gtgcttgttt ggtataaaat
     5401 ggtataatgg agatagagaa ttatattaac caaaaaatgg agaaaataga gaagatgatt
     5461 tagttgacgc tttatcagta ggagtacctg taggtaagac agaatctcta gtacgattag
     5521 ttggagatgg aataagtgat actcaaaaaa gtttaataaa taaaagagaa tttagaaata
     5581 taactcaaat tggtggaaat ggaaatgaga aagcatttag tgaagtagaa aacttagtta
     5641 aatagattag aaggtagcaa ctagagttgg ttgttacctt ctttttttat actttctctc
     5701 tctaagtatt ttatttttca tatcttcgaa tacatctaat gcagtagtat aaaattgtat
     5761 attatttcta taaggtatag ctattggaag aatgcccttg ttaactaaaa aaataagaag
     5821 tacaataaat aaaagtgtca taatcattct aataaaataa ttagtgatat ctgataaatc
     5881 aaatgttaag ttaattgttg tagaaaatac aacagccata atagatatat acaaagcaaa
     5941 aatggggtta ctattttttt gtaactgtcc tttaagccta gattgctcta tttctatatc
     6001 ttgaatactt tttatggaat ccatttcact ataatactta taaactttta aataatattt
     6061 tttatacttg tttaaagctt cttcattatc tttaaggtct ttgtcactta actctgattt
     6121 aacttcccca aaatccataa aatccctcct acaatgttat ataatatact ttaatttata
     6181 gcatatttaa gaacttatat cagcaatttg tcgaacgatt ttagctaaaa atagagtata
     6241 atgataggct tattatttat aagatattat tttttatata gttatatatt tctttctaat
     6301 tagataatat aatgctgttg ttataatggc tactaatatt attgctatta ttgtaatatc
     6361 taatcttctt gtaaataagc ctattgctat atactcaaga cctgttacat agcgataaag
     6421 tacttctagt ttaacagttt ttttcttatc tatatttcca tatattgatt ctaatttatt
     6481 aaaatatttt ttactacaaa aagcagtttt aggtttaatt aaatatatta ttgtagttcc
     6541 tattataact attattccaa taagtataag attgatattt ccaaaatcca tagcagatac
     6601 ctcctattaa atttgctttt cttaatcaaa gtatatcagt aacacaagta caaagagtat
     6661 ctaaaatatt acaaatatta acaggataga taaaactata gtaaaaattg taataataaa
     6721 gcgaacgaaa attatcatac taaaacataa gacatgttat aattgtatta gatagaagat
     6781 taacatacac caaagcactc cttataataa agagtgctta tttttttgaa attcatcaat
     6841 atataaacta tcaagaacct tattcaacac accttaaaat cgatttaaat agctcttttt
     6901 gataacataa tttatatgat ataataaaaa aatagaagtg taccaccaat acacttctat
     6961 agctataact aagcattctc ttgctggggg agtgcttttt tcatttctcc aaacaacatt
     7021 atttacttca tcagtaatta tcaaatcaat ctcattatct ttcaaaatct ctgttgcagt
     7081 acaaattaga ttatctaagt caaaacttcg agttatctct agttgtttgt tatttacttc
     7141 tctttttagt atataagttt taaaatacat ttatatcacc ccttgtattt actctttttt
     7201 ctctaaaaat atattgataa gtaaatatgc aacaaataaa aaaatctcaa tgacacatag
     7261 tgttatagct ataactagaa gtgattgatt tttccatgca ctataagcta tgatgaaaag
     7321 aaatgtaaaa gtaaataatg tataattcat aattttaact aagatatgac ttgttttcat
     7381 tgttaagtac aagtctcttt catctgtact atcgtgtaat tcttcaacaa tgccttttct
     7441 tgaaaaagca ttacaaaaat taaagattgc tattacaatt aaaagaaatg atgaaattag
     7501 gaatctttta tcttttaaaa tgcaataaat aactaaacta gcacaacata acacacaaac
     7561 tataataccc actataaaac ttcgtttact ctttactttc atgtttttta tcctccattt
     7621 ctttattttc ttttaaacaa catagttctt caatcgttgt accaaacact tgtgccatac
     7681 gataggcaag cataagagaa gggctatatt gctctttttc aatagaaata attgttctgt
     7741 ttgatacatg gactaaatca gcgagttgtt gctgtgttag acccatattt gttcgaaatt
     7801 ctcgtacttt tgttttcatt ccataacctc tttctatatg aagctaactt catgtgaagt
     7861 taacttcata atatcctaaa atgagtaaaa tgtcaatctc attagataag tattataaaa
     7921 cctaaaagaa taatatggta aaaattggat ggaattattt accttaattc tcttgtttgt
     7981 aaaactttat tgatatagaa tttaacatat acataaatcg gcaaaggggc gcgaattatg
     8041 aaaattagta aattaccaga agcggaatta aaagttatga gatatatttg tgaagctaac
     8101 aaggtattaa cttctaggga attagttgct gcaatggaag aaaaatatga gtggaatgaa
     8161 tcaactacat ttacagtttt gaaaagatta gagcgaaggg agtttttaag tacagagaaa
     8221 ataggcaaac ttacacatta taatatacta gtaaaagaga aaaaatatct aaggtttgaa
     8281 acaaaggaat ttttgaagaa catacataaa aattcaattt caagtttaat gtcagcgtta
     8341 catggtgaag acgacgaagt ggatgaagat aaattaagtg aactcgaaga atgttttaag
     8401 aatttgaaat aagaaaatga caaattgata cataataaat aaaatgaagg tatgaaatta
     8461 taactttttc taccttcatt ttgtttatta ttctgaacat gttaagaaaa tgaaataagt
     8521 ttgtatttta gttatataaa ttttaataga atatgtacag tatatagtag atagaatgta
     8581 taaaaataga atttaaataa gtagctatta ttgcagtgaa atgaatgttt ctaagtatat
     8641 ttgggtggaa gaatggtgga agaaaattag tgaaatgtaa ttcttccacc attcttccac
     8701 ctagaaaata gaaactgttt aataagaatt aatatacatt aattcagctg aatgcaatca
     8761 aaatacttaa atgaaagtaa tctgaaaaca acataattca aatcaattta ttcaaataaa
     8821 cctcaattta tcttaaatct taagaaatat ttaagaatta ggataatatt ttcttaagat
     8881 ttatatttta ttatatagtt ataagggaaa gttacaaaaa tgtaagccaa agtaatataa
     8941 caatttagtc attgttgaga aagggagtga aagatattgt ataatataga taagtattat
     9001 tatacaatag aggaagtgaa aatatgtaca atatattagt agtagacgat gataaagaaa
     9061 ttgttgattc gatagaaata tatcttaaat cagaaggatt taaaatatat aaagcatatg
     9121 atggaatgaa agctttggaa ataataacag agaatgacat tcatctaata ctaatggata
     9181 taatgatgcc taaattagat ggaatcaaag caactgtaaa aatacgagaa gaaagaaata
     9241 ttccaataat tttaatttca gcaaaaagtg aagatacaga taaaataata ggattaaata
     9301 ttggagctga tgattatata acaaagccat ttaatctatt agagcttata gctagggtta
     9361 aatcaaactt aagacgatat gtaactttag gtaattatga agatacatgt aaagaaattt
     9421 taaaaagtgg agctttggag ttaaatacac taacaaaaga agttaaaatt gatggtgaaa
     9481 acataaaaat gactccaatt gagtataaaa taattgaact tcttttagaa aataaaggac
     9541 gagttttctc aatagatgag atatacgaaa aagtatggaa tgaggaaagt tttaattcag
     9601 aaaatacagt agcagtacat atcagacgaa taagagaaaa gattgaaata aatccaaaag
     9661 aaccaagatt tttaaaggtg gtgtggggag ttggttataa gattgaaaaa ttttagtgga
     9721 aaaattataa aagaaaagag tttaatattt aattgcattt tgattttagt catttttaca
     9781 tttacacaaa tgttaggaat tttaatatgt tttaattttt tctctgagag tttaatttac
     9841 tctatgggga ttatgctttt cttaaacttt attttatata aaatactgac aatgtagatg
     9901 aggtgggcaa cttggagaaa tatagagtat taaagttagt ttcattaatc ataatatcta
     9961 tctcatttcc attaactata ttgttggtga caataggact tgctgagcct aaatacaata
    10021 tacaaaaaac ttctacaaag agtgggattt ttgatatatc tgatgatttt tatgatagta
    10081 atatatttga cgaaggaaca atggcaagtc tattacccaa gtttaagcta tctgtaggtg
    10141 gtaaattaac tagtaaagaa aaaggtaaat tccaacaaga aggtaaaagt atagatttaa
    10201 gtagtagtga ttctgagtat gataaaatca tgattaatga acaagcttct gaagaatatt
    10261 taagttatct aaaaaatata aaagtgtatg ttattaatac atacacagga gtattttata
    10321 caaatacgtc atatgctagt ttatatgatt ttaaacaaaa aactaagagc tattgtaatg
    10381 tagagataat aaataagata ggaaagagct catatattaa aacaataaat ggagaaaaat
    10441 ttgaactgaa taatctgagt ctggaactaa atgaagtaga tgaaggtttt gaggcatatg
    10501 tatcttttcc agaagagcca actatagaag atggaatagt atatactaat tttcaaatat
    10561 ttaaacaagc tacagaaaaa gtaagattat tttttgtagc tagtttaagt ttagcaatta
    10621 tatgtttatt atctataatt ttatatatca aaataaaagg tgaagtttta aaaagaaata
    10681 atgtattttt actaatatac agtaagatac ctatggaatt taatgtaata ttagtatcta
    10741 tttcaattgc aattttaact atatatgctc ttgctgtatc ttatcatatt gatgtaattg
    10801 cattagtttc tttatcttta ctgatagtat caaataatat attttttata aatgtgcaat
    10861 tgagttattt agaaaataaa atgtgtatat ttaagacaag tattatagta agagtgattt
    10921 tatggttaat aaaaactgta agggaggtca gtaacgctat aaagaaagta tctttagcaa
    10981 ggaaagttat tgttatagtg ataatatctt tagctttaat catggtaatt agcactcgaa
    11041 gtataggtat gggattactg ttttctatat gtattttttt aggatttaca atatatataa
    11101 ctaaaagact ttcatatctt agttacgtaa tagaaggtac agaaagaata aaaaagggag
    11161 aattagatta taagataaaa attactggga atgataattt tacgtcttta gctgaaaata
    11221 taaataatat tggagaaggt cttgatagag ctatagaaga gcaagtaaaa agtgaaagaa
    11281 tgaagtctga ccttataaca aatgtatctc atgatttgaa aactccactt acttctataa
    11341 taaattatgt agatttaatt aaaaaagaag aatcaataca accagagtat ataaatgatt
    11401 atataaatgt acttgagtca aagtcaaaaa gactaaaatt attgatagaa gatttatttg
    11461 aagcgagtag agtaagtagt ggcaatatag aattacaaat tagcaagatt gatttagtgc
    11521 aactattaag acaaagtata ggtgaacttg aagaaaaatt atctaaaaat aatttatatt
    11581 taaaattaaa tgttccaaat gataaggtgt atatatgggc agatggaaga agaatgtata
    11641 gagtatttga aaatctttta tctaatatag caaaatattc cttagaagaa actagagtct
    11701 atattgatgt atatgactat ggtgaaaatg taaaggtaac tatgaaaaat atatcttctt
    11761 atgaattaaa ttttgaccca agtgagatta tggaaagatt taaaagagct gatgaatcaa
    11821 ggaatactga aggaagtgga ttagggcttg ctattgcaag agatttagta gctttacaag
    11881 gtggaaaatt ttatatagaa atagatggag atttatttaa agcaaattta gagtttcaaa
    11941 aatatgaaga agaaataaca aatatggaat gagatagtat ttaagtatat atattttttt
    12001 tactgtcgaa agcttttatt ataatatatt agaatattta cagtagagaa tgaagagtaa
    12061 aaacagagta actttaagtc actctgtttt ttatttaaaa tcaataatat aacaacttaa
    12121 attaaaattg tacacatagt tttaaaataa cttatacaat aaaacattat ccaaatatca
    12181 caagataatt ccaaataaat atatagatat cactcctgta ataatagaaa taccaataga
    12241 tttaaactta tatgcaacaa gaagtacaat cataaaagat ataattttag ggttagctat
    12301 agataaatat agactatctc cattaaaaaa tacatcttta gcagttaagg aagtaagtat
    12361 tgctacaggt ataaatttca tgattttttt caaaaaatca ggcatctctt tttttgaaaa
    12421 aattaacata ggaagcactc ttggtagata tgtaacaatg tacattccaa ttataataaa
    12481 aaatatataa ttattattca taagattcct cctttttaca gtaagattct tctataaaga
    12541 aaccaattaa agatgctaaa attgatgcaa ctattattac taaattgctt ttgaataatg
    12601 catataaaat aacagaaata atgattgatg atataaatac tacaatataa atcttatttt
    12661 ttatttgaga aactattaaa gctataaaca tagaagtcaa tatgaagcca gaaatagaac
    12721 tgtctataga tatactttct cctaaaaatg ctccaataaa attagctaaa actgatgaaa
    12781 ttaagcagaa gaaattaaga taaatagcat ttctatcaga ccaatttcca gcagtaaatt
    12841 tttcataatt aactgcaaaa gtttcatctg ttatagtatg acaaaatggc aatataaatt
    12901 ttggactttt attttttatg tacatgttca aattagaact cattagaaaa tgtcttaagt
    12961 taactataaa tgtagtcaaa acaatagatg ttacacttgc accagtagaa atcattgaag
    13021 ctgcaatgaa ttgagaactt cctccaaata ctaaagttac cattagtgct atttgaaaag
    13081 gtgaaagacc agatttttgt aatagtattc ctcctactat acctataggt atataaccta
    13141 agaatatagg aattgaagca ataaagcttt cttttaattg ttgagttctt tccacaataa
    13201 atcactcctt ttgtattaaa tgtattaaag tattcgtaaa acagaaaaat agattaattg
    13261 tataattgca attataatta aaaataaatt tggattaata tataaaatac tatacaacaa
    13321 atagataatc ttaaacggtt attaaatttt atctatttgt tattatgatg taataataca
    13381 tattaatctc tataagttaa ttactatctg gtgtaatttt attttaacaa caaaaaaaaa
    13441 tacacacaat taaaatattg tgtgcaatac aattattttt tctcttctaa tagtcttttt
    13501 aatacgctca aaccagcttt aagttcttct gtactttctg tagcacatac agctattctt
    13561 attgcagaaa ttggtttttc ttttccaaca gcaaaacgtt cagaagcata gacctgtaca
    13621 ccttctttaa gtgcttgtat ctcaaatttt tctgccatta ttccatcagg tagaatcaac
    13681 catctaaata tacattcttc atttcccaaa agattatatc cagataaata ttgattaata
    13741 atcttgtttc ttcttcttgc agatttacgg cgtgcattaa ttaatttatc ggcttcacct
    13801 gatgtaatca tgcgataagc aatttctgtt aaaaaataag attgagatag attaatgttg
    13861 tataatgcgc ttgataatgc ctctcgatac tgtttaggtg tagagatata tgctagccgt
    13921 aaactaggtg caataatttt tgataaactc gtaatataaa ttgtttgatt gggcagatag
    13981 gaagccactg gatttaaatg tgtttcatta agtaaactat gaatagcatc ctcaataaca
    14041 attaaattgt atttagatgc aatatttgca atcatttttc gtccattttg tgacattata
    14101 tgtgtagttg gattttgata atctggtatt atgtatagac ctttaatatt ttcattttta
    14161 caagcatata atagtccttc ttcactaatc tcattatctt cttgtttaat tggaattagt
    14221 tgaatcccaa gcattttagc tgctgtcttt attccaggat aagttaatgg gtctacacct
    14281 attctatctc catgttgaaa caaaccagct aaaatagcaa caattgcatt ttgtccacca
    14341 cttgcaggaa gtaagctatc tgatgtagtt tcaagcccag ctttataaat taatttggca
    14401 atagcttctt tttgccattt agcaccatct ctttgtccat attggaatat agttttaaaa
    14461 tctatttcct taattatgtg tttaaacaaa gtattcattt cttctagcgt gaaatctgga
    14521 ttcattgtgc ccatttcaat aaatgtaatt ttattattac tggacatcaa gaatagattt
    14581 gaacgtgtat cataagatac aaaagttcca cttcctgtaa ctccacttat tagacctttt
    14641 ttttcacaaa ttttaaaagc tctagagata gtactcacat taacatctaa gaaatctgcc
    14701 aattcacgtt ggggtggtaa tttagtacct ggtaataaaa atccattgtt gatatcttgt
    14761 tctagttgtt ctgcaagagc cttatataat atttgacctt ttgaaggtct ctttggtttc
    14821 cagttcatag gataattttc aaaagaatta attggcataa gttttcacct cacattatta
    14881 atttgatttt ttctttatct aaaacaataa attctaaaga tacaaataaa aactgatagg
    14941 aaataattct atcagttttt gtcttttaat tgatttcaaa tcttcctata atttttatac
    15001 cttctttatc ataaagaggg attgtttttt taaatatatt aaaatttctt tttcttgtat
    15061 ataaaacagc ttcttctggt gtctttggtt gattatcaca atcgtacaaa tttctttttt
    15121 ttaactaaaa gcaataatac ataaaattat tattgctaat gatactctta atgtggtata
    15181 tagtcatagt gtcacatgtc tatcaatagt tttttcagta attattgtaa cgaatagtag
    15241 gactcataaa atacttagaa atatgttttt agataaattt taaatatata atctaactta
    15301 tatctataaa ttaacactat tattctccaa ttccatttct agttttttta taaatttatt
    15361 aaattcttct ggttgccttt ttccaaacaa tactcttaca agagctgaat tgatttttcc
    15421 aaatatattc ctcttgctct cactttcaat aaaaataagt tttgtatttt ctaagtcaat
    15481 atgtactaat tcatatctag taatagtact ttctctttta ttgcttgttt ttatctcata
    15541 tactctattt ttttcgaaat tagttatttc aaccttaaat cttttattat ttttttgctg
    15601 tacaaatgtt cctactgctt ttttctcatt aaaattagga aaatttagtc ttgcagattt
    15661 tgtaaatata ttaaatatgt cttttgcaga atattttaat aaaacttcag ttttaaatgt
    15721 attcatatcg ttttcccttc tgtatataaa tttaatattt ataagttaat ttttaagtta
    15781 aaatagtata atatgccata ttaaatcatg ttaaaactat ttatatagct aaaatcttac
    15841 ctatataagt atgtatacta tcatataaaa ataaaatctt aaaatagaaa gggttaaaaa
    15901 cacagtttat tataattttt attgttgagt agatacgtac tattatatat gattgagcaa
    15961 gtttttcaat cataaattta taaagtattt tgcattaaaa tttaaacaaa gaattaaatt
    16021 atttaagatt atgaataact aatacattta gtaaattact aaatatacaa aatgtaaata
    16081 cttatcaaaa tgtataaata cttatgacat ctagttactt acagggttta agtagaaaaa
    16141 aatatcaaag taagtatggc atgatagttg cttatatatt tatcaagaaa ggagttatta
    16201 agcatggagt tgagagataa acttgtaaac atcataaata cagaaaataa aaaagatcca
    16261 ttaacagatg ttcaaatagc aaagttttta agtacaacta gagagaacat aactaatttg
    16321 agaaaagaac ttaatataag taattcaagg caaagaagat atccttattt aaaatcagca
    16381 atttcggcaa tattacaaaa gaataagaat atttctatat cagaaattac aagggaattg
    16441 atgacagaag gctttaatat atctagaaga gttgtggagg aacttttacc taaagaaagt
    16501 ttagaaatgg atgtagtaga ggaatctgaa gaagaatcga atgacccatt tgaaactctg
    16561 ataggtaata aagggagtct tagaaatgct gtagagcagg ctaaatctgc tatattgtat
    16621 ccaccaaaag ggttaccaac gttgattatt ggggaaagtg gagttggtaa gagtttattt
    16681 tctagacata tgtatgagtt tgcaaagcaa aaaaagatag taaaagaaag ctccaatttt
    16741 gttgtattta actgtgctga ttatagtgac aatccacaat tattattatc tttgttattt
    16801 ggatataaaa aaggtacatt tacaggtgct gaatatgata caccaggtct tgtagaagaa
    16861 gctgatgaag gagttttatt tttggatgaa atacatagat tgcctccaaa aggccaagaa
    16921 atactatttt ctattttaga taggggaaag tttaggagat taggtgaaac taatgctgaa
    16981 agaaaagtaa gtattatgtt gattggggca actactgaaa atgtagagac taatttatta
    17041 ttaacattca gaagaaggat accaatgcta ataactttgc caccattaca tgatagatta
    17101 ctaaaagaga aaatagacct tatatacaat atctttcaac aagagtgtaa tagaataaat
    17161 gcaaaaatat ttgtagataa aaatgtgatt gaaatacttg cactaaaaaa gtttagtgga
    17221 aatataggac aattacaaaa tatgattcag gttctttgtg caagagcttt tatgaagttt
    17281 ataaattcca aagatgaaga tagtgaatcg atagtagtag tagatataaa tgaagtttta
    17341 aagcttaaag attcttttaa agatgctgcc tttcaagaga ttgaatatac agagataaga
    17401 aaatatttga aaaatgctat atttatacca tttaatttag aagaatcatc agtaaaagga
    17461 agtcttttaa gtgatgaata tatattacca gaggacatat acaaaacaat tgaaaagaaa
    17521 tattatgacc taaaatccct agacattgaa gatatagata tagagaatat tttatggact
    17581 tttattttaa atagatttgc tgacttaaag tttaatctcg atagtaatga agaaattttt
    17641 tcaatgagtg atttaaatag ttttgtaagt gatagtttag ttaaactggt aaaagaactt
    17701 atgaatgata tagttgaaaa aaatatgaat ttagaagtaa ataaaaatat gttcaaatat
    17761 ctagcaatac acttagaaga agctataaaa agaattaagc taaatcaaaa gataataaat
    17821 gtaaatttag aaaaaataaa gattgacttt tcaaaagaat atgaaattag taaaagtttt
    17881 gcaataaaaa ttgaggaatc aattggtatt aagattccag atgatgaaat tggatttata
    17941 acactctaca taaagtctgc tctaaaaaat gaagtgaaaa aagataaagt agggttaata
    18001 ataatttctc atggacgtat agctacagag actgtaaatg tagttaaaga acttttaggt
    18061 gtaaagtttc ctgtggctat agatatgcct ttagatgaaa aaccaataaa tatatacaat
    18121 aaggcagtag aactgtcaaa aataatagac caagggaaag gcatattgtt tttggtggat
    18181 attggttcac ttacaaacat aggtcaaata gtaaataaga gaaccaatat aagcactaaa
    18241 actattgata gagtagacct cctaatggca ctagaagcaa ctagaaaagt ttctatggga
    18301 gaggaagaac ttgatgaaat atttttttct ttgctaaaag ataggatggg atataactat
    18361 gaattagaaa aacacataga taaatcaaat gcaattataa cattatgtct tactggagaa
    18421 ggaactgcta agtatataag taaaacgttg gaagaaaagt atgataacac taaatgttat
    18481 caaatgagtg cattggatga aaatttattt tgtaaaattg aaaatctaaa agagacaaac
    18541 aatatattag ctattgttgg gacaataaac cctaagatac caggtataaa ttttataccc
    18601 tataataaag aacttttcaa aaatttggat atctatctat caaaatcaaa acaacaagat
    18661 gacagaccaa ttaaatcgta tgaaagaatg cttgatgagg atttagtgat ttttgaacca
    18721 gatatatatt ttaaaaagga tttattagaa tatgtatgtt caattcttat aaataaagaa
    18781 tatgtagaaa aagattactt agattctgtt ttacatagag aagaaatgct tccaacatat
    18841 tctaaaggag ctataggtgt gcctcatgga gattcttcta ctgtaaatag tacaaggttt
    18901 gtttttgtta aactaaagaa tcctattgat tggggtgtag gtaatgtaaa tttcatattt
    18961 atgccagttt ttcaggctaa tgataaagag attgttaaaa atgttcttga gatactaaaa
    19021 gatgcagaat ttatgaacaa tgccaataag tgttttgata aagatgcttt tagaaggatt
    19081 atatttgata aatttaaaca tctgtagcca tagcaaaaaa attgagagga gttagagtaa
    19141 tgaatgtaga tttaatatca ttgggtttag aatctaatga ttatgaaagt gttattgaag
    19201 aattaggaag tataatgtgt aaaaaagaat atgtaaaaga aacatacata aatgctgtct
    19261 tggaaagaga aaggacatta ccaacaggtc tagatattgg agaaatgtgt gttgctattc
    19321 cacatacaga ttcaaagcat gtaaatgagt ctaatgtagc tgtagggata ttgaaaaatc
    19381 ctgtaaagtt taattcaatg atagacccaa aagatagact tgatgtagaa cttgtatttt
    19441 tattagcagt aaagaaccca gattcacaag taaaactgtt aaaggattta atgtcagttt
    19501 ttcaaaatat aaagttatta aaaaatataa aaaacgcatc aacaaaagaa gaagtagcta
    19561 aattattgga ctttatagaa atttaatgta ggagaatttt ataaataaaa aattaaaatt
    19621 taaacaatca aagtaagtat tattttttta ataggtttaa tcttatataa aataaaaatt
    19681 tagagtgaaa aattaggagg aaataattat gaaacaattt aatgtattat cagtttgtgg
    19741 ttcagggaca gttacatcat ctatggtagc aggtaaatta aaagaagtac taggtaataa
    19801 ggggatttct attactacaa cagaagctag accaacagaa gcactaaatt tagcacaatc
    19861 aggaagattt gactttataa catttacgag tccacttcaa acaggcgatt atggaatacc
    19921 aactataaat gcatttgctt gcctaactgg tataggggaa gaggcattct ttgaagaagt
    19981 tttgactgtt attgaaggga tagataagta agttttggag acgtgaattt atagtattta
    20041 aatcaatgac ttagatacta taataagcta atattaacta aatatttgtg gaaaaaacat
    20101 tttatatgtt gtcataaatt aaaaaattat aaaaatagtc acttaagtat taaattaagc
    20161 ttataaatat ttataagtag gagggaaaaa gatgttagaa tttatgaaat ctataatcga
    20221 tacatttggt tctgcaatta tagttccaat tataatattc ataatcgcaa agatatttaa
    20281 agtaactact aagaaatcgt ttctttctgc tgtgtatgca ggagttgctt tacaaggttt
    20341 tacactgatt ttaaattcat ttacaccaat aataacacca gttatcaata ggatggttga
    20401 gagtacagga gtaaacctac cagtttttga tgttggttgg caagcaacat cattggttgc
    20461 attttcaaca agtgcaggta tgatatattt aggtcttggt atattattac aaacaatttt
    20521 atttttgata aaatggacag acgtgtttca accatcagat ttatggaata actattctta
    20581 tatggtatgg ggagcaatgg ttataggagt aacaggaaat tttcctttag gtatagcatg
    20641 tatggtttta ttaaacctat atagtttatt aatatcagag ttagttgcaa agagatggtc
    20701 tagttactat agatatccta attgtacaat aatagctatg cataatgttg aagcttctgt
    20761 gtttgcagta tttgcagacc ctatatacaa taaattggga ttaaataaaa taaaattaaa
    20821 tccaaaagaa ttagagaaga aattagggtt tttaggtgaa ccaattactt taggtctttt
    20881 tttaggtatg tttataggta tattaggtaa tatgacgaga ataaatacta tggaagcttg
    20941 gggagaaata atgaaagtag gtatatctac aagtgcagtg atggcaattt tccctaaagt
    21001 agcaagtatg tttgctcaag catttgcacc tataacagaa gcagctagaa agattatgca
    21061 aaaagctgga aaccgtgagt ggtacatagc agtaaatgat gctgttggat atggtgaacc
    21121 tgcaacttta atatcaggtc ttatattaat tccaataatg cttgtaatag ctatggtact
    21181 tcctggtaat aaggtattac cagttgtgga tttattggca attccatata tggttcaagg
    21241 tttagttgcc atacataatg gtaatatacc aaaagtatta gtttcaggta taatttggtt
    21301 tggattagga ttatatgttt gtacatctac agcaccatta tttacagata tggctacaaa
    21361 tataggtgta gctatacctg caggagcaat gttaataaca agctttaata tactaggaaa
    21421 acctttgatg ggattagttt tctttgcatt tctaagtgca aatccaattt atataggtct
    21481 ttcagttgta atttactttg ttctatgggc attgtttaga aagaacaaaa caagtattct
    21541 tgattattta gaaaaacaag cactcaaaaa tgtagaagaa gagcctgtag cagtttaagt
    21601 ttataaaaat gaaataaaaa taattaaagg agtttataat tgattttata taagtatcag
    21661 ataatacctg agaaatattt aaatgaaata tagacttctt tttatttgat aatatttgta
    21721 attataatgc attgtatttt tatagttgag ttttctgtat aacctgctat ttaaaacata
    21781 ctcttttata tttatacagt aatgtggttt aattttataa aatgtaatct ctactggtaa
    21841 aagactttgt atataaggca tttgcctgaa taaaccattt atcttttgta tggcatagat
    21901 attgctatat agaagtatat agtatgaaag gagatattta tatgggagat aaaatgagag
    21961 catcagtatt gtataatgta ggtgatgtca gatatgaaat ggtagatata ccagaaataa
    22021 cagatacgca agtgcttgta aatgtaaaat atgttgggat atgtggttca gatttaccta
    22081 ggtctatggt aagtggtttg agtggaaata caaaatatcc attgatttta gggcatgaat
    22141 tttctggtga agttgttaaa attggagaaa aagtaaagca tattaatgta ggagatagag
    22201 tagctgttgc accattagta ccttgtggaa aatgtgatta ttgtaatgaa ggtaattttg
    22261 gcttgtgtga tgattacaat ataattggaa caagagtaaa tggagcgttt gcagaatatg
    22321 taagagttcc agaagaacat attttaaaac taccagatac attggattat gaaactgctg
    22381 ccggaattga accagcaact atagcttatc atgggatttc aaagtctaat attagagtag
    22441 gagatagtgt agttgtgtta ggatgtggtc caataggtca gtttgttata caatgggcaa
    22501 aggtgtttgg tgcatctaag attatagcag ttgatatttt tgatgaaaaa ttagaacttt
    22561 ctaaacttct aggagcaaac tatatactta actcaaaaga agtaaatgta atcaaagaaa
    22621 taaaaaaaat aacaaatggt ggtgctgatg ttgtaataga aactgctggt agccgattta
    22681 cacaagaaca atctctattt gtagcaaaaa agagaggaaa tatagtgttt gtaggtatat
    22741 cacacacaga attaccactt agtgcagacg ctactgagtg tatattacgt ggagaactta
    22801 ccttgaaagg ttcttggaat tcatatacaa gcccttatcc tggaagagca tggactgcaa
    22861 cattggattt tatggaaaaa ggtgacatta tttttaaacc catgatttca gataaaatag
    22921 gtcttaatga agtgggtgac tttttaagta aaatgagcaa gagagaaatt aatttcaata
    22981 aaatcctagt agaaatgtaa aaatttaata aaaaattcta aaagcaatta aattttataa
    23041 ctatgacatt aaataaaata aaaataattt tcttaaataa aatataggag gaagaaaagt
    23101 gttagaaaat ttaaaagaag aagtattaaa agcaaactta gaattaccta agaaaaagct
    23161 aattacttat acttggggaa atgtaagtgg gatagataga gaaaaaggat tagtggtgat
    23221 aaagccaagt ggtgtagagt atagtaatat gactgtagaa gatatggttg tagttgattt
    23281 agagggaaat atagttgatg gcaaattaag accttcttca gataccccga ctcatctagt
    23341 tttatataaa gagtttgaag aattgggggg aatagtacat acacattcaa gttgggcaac
    23401 aatttgggct caaataggaa aatctatacc atcttgtggt actactcatg cagattattt
    23461 ttatggaagt ataccatgta ccagaaaaat gactagagaa gaaatttgca atgaatacga
    23521 aaaggaaact ggaaatgtaa tcattgaaga atttatggga agaaatccaa ttcattgtcc
    23581 aggaataatt gtaaatgacc acggaccttt tacatgggga aaagatgcaa atgaggctgt
    23641 acacaatgca gtagttttag aagaagtcgc aaagatggct tattatacag agttaatgag
    23701 tcctgataat attatggata aggttcttat gaataaacat ttttcaagaa aacatggaaa
    23761 aaatgcatac tatggtcaaa aatgattatc tggaggtgaa ttatgctaga ctctttaaaa
    23821 ggtaaagttg tggaaatagc aattaaagca gagcattatg gtttatgtaa agaaaagact
    23881 ggtaatttta gtattagaga taaggatact ggatatatac ttataacccc atcaggtgta
    23941 ggaagagaag aattaaaagt tgaacatatt tgtgtattgg atttggatgg aaatgtaata
    24001 gaagttgaga aaggtattaa gccaagtagt gaggtattga tgcatattga aatatacaaa
    24061 acaagagaaa atataaatgc catatcacat actcattctt tatatgcaac agcattttca
    24121 gtagcaaaga aaccaattat accaattgta tatgaatcag ttaattatgg cggttatgta
    24181 gatattgctt catacgaaag accaggaact ttaaaattag ctaagagtgt ttcaaaatta
    24241 ctgatagata cagatgcatg cttattagaa agacatgggt tgacaactgt aggtaatgat
    24301 ttagacgaag cattattaaa atcaagatat gtggaagagg tagcagaaat atactatagg
    24361 tctttagtat taaatcaatt taaagaactt gaagtagtag atgttgatga gtttaaatct
    24421 tggaaatacc cagaagaaat aaagttttaa tctaaataat tttcattgaa gtggttaatt
    24481 aaaatatatg tattatttat atcaattact atgttttatt atattaatta ccgtattttg
    24541 taaatatatt tattacattt tttcaaaaaa atatagaatc caaaagccat ataaaattga
    24601 cttgggattc tatacttttt atttatgcat ttttctttat ctgattttct ggagaattta
    24661 tatgttcaaa atatttttta gtttcagata ctattatagg tgataatgca agtaaagcta
    24721 taaggttagg tattgccata agcccattta caatatcagc aattatccaa acaacttcta
    24781 actttaagaa agcacctaat aacaccatag ccacaaatac agttctatac ccattcatgc
    24841 cttttacacc aaacagaaat tcaaaacatc tttctccata ataactccat cccaaaattg
    24901 tagtaaatgc aaataatgtt aaactaattg taagtaatat tggtccaaat gtaggaattg
    24961 ctccgttaaa agctgcttgt gtcataacag ctccatttag gtctgaacac cacactcctg
    25021 aaataacaag agagaatcca gtaagagtac agattataat agtatctata aaagtacctg
    25081 tcatagatat aagaccttgt tccgctggcc attcagtttt agcagcagct gcagctattg
    25141 gagcactacc tagaccagac tcatttgaaa atacaccacg agcgatacca tttctaattg
    25201 ccagtgacat agttgctcct aaaaaaccac cagtagcagc agtaggtgta aatgcacttt
    25261 taattattaa cataaaagtt tcagggattt tattccaaaa agatattaaa atgattccac
    25321 agattacaac atatataact gccataaaag gtactatttt agtagctaca ttagatatac
    25381 ttttaagtcc tccaaataca actaaagcta caaatactgc taatacaacc cctgtaattc
    25441 tagggtctat cccgaaacta ttatttattg catctgttat tgaatttact tgagtaaaag
    25501 taccgattcc taaaagtgca actagtatac cacttatagc gaaaaatatt gcaagaggtc
    25561 tccatttttc tcccatacca tttactatgt aatacattgg cccaccagac acttgaccat
    25621 ttttatcttt agttctgtat tttattgcaa gaacaccttc tgaatactta gtagccattc
    25681 caaagaatgc tgctatccac atccaaaaaa gtgcaccagg tccaccagct ttgatagctg
    25741 tagcaacacc aacaatatta ccagtaccaa ctgtagcagc tagagcagta cataaggctg
    25801 caaaacttga aacatcacca ctacctttgt tttcagcaga gaatattaac ttaagagctc
    25861 ttggcagttt agttatttga acaactccaa gcttaacagt aagtagtata ccagtaccaa
    25921 ctaatagtac cagtaggggt ggtccccaaa taaaagcatc aactttgttt aaaatatcaa
    25981 ttagattcat aaaaacactc cctcattttt tttgctttac ataatcaata gaatttttaa
    26041 tgaagtaatt gacaggaaat aagtataatt tattaataat ttctagtgta ataaaaaaag
    26101 ctaaatctaa aaaagattca gctctggatg tacactaatt agcaaccaaa ataaaagtat
    26161 tagtaaatac tgtttttggt agataatccc tgtccttttg cctgagagat tgagcataaa
    26221 agccttgccc cttcggcgcc cataatgggt ctctccagag ttccgtaaat tttacagtcc
    26281 tacttttaaa agtacctgag agtgttactc cttcggtgtg ctatatagca actcttctat
    26341 aaaatcttaa ccggatattg atttgtcata gcttattgta ttaataatat taatataagt
    26401 ttttatgttt tgtcaactaa aaaattaaaa aacaaagaaa aaatataaaa atgtaagcct
    26461 atttacgaat tataaactta gaaagatgag taatatacgt gaaaatgaat tttgtaatac
    26521 acatacaaat gaagtgtaaa ataagtttta aataaaaaaa taataaaatc ttaaataatt
    26581 aattagatat gattaaatta tggtaatatt atagttacga tattaagaaa agttctattt
    26641 agttagattt taagcgtaat atgagattat gtatagagaa aggatgtatt tttagatggg
    26701 aaaaatatta gtgctagcag aaaaaccttc tgttggaaga gatatagcaa aagttttagg
    26761 gtcaaaaaat gaaaaaaatg gttatataga ggggccaaag tatgtgataa cttgggcact
    26821 aggtcatttg gttacacttg ctgaccccga aagttatgga gaaagatata aatcatggag
    26881 cttagaagac ctgccaatac ttcccaagca ccttaagact gttgtaataa aaaagagtgg
    26941 aaagcagttt aatacagtta aatcgcaaat gaatagaaat gatatagatg aaatagttat
    27001 agcaacagat gcaggtcgtg aaggagaact tgtagcaagg tggataatag aaaaatcaca
    27061 ggtaaaaaaa cctataaaac gtctttggat ttcttcaagt acagacaaag caataaaaga
    27121 cggatttgca aaattaaaaa gtggaaaaga atatgaaaat ttgtattact cagcaatagc
    27181 acgagcagaa gctgattgga ttattggaat aaatgcaacc agagctttga caacaaagta
    27241 caatgcacag ctttcttgtg gaagagtaca aactcctact cttgcaatgt tgcttaaaag
    27301 agaagaagaa ataagaaatt tcaaacctaa agagtattat ggattagaat taattgctac
    27361 aaagggaaat tcagatataa aatttatttg gaatgataaa aacaataatt cttcaacttt
    27421 tagtaaagaa aagatagaat ccacattaaa aaaagtaaaa ggtgtagaca taaaaatatc
    27481 tgaagtaaac aagtcatata agaaaaaata ttcacctgca ctctatgatt taacagaatt
    27541 acaaagagat gcaaataaaa tgtttggatt ttcagcaaaa gaaactttat ctataatgca
    27601 aaaactgtat gaacatcata aagtacttac ttatcctaga actgattcta gatatttaac
    27661 atcagatatt gttggaacat taaaagatag aataaaagct gtaaatatta gtgattattc
    27721 aaagatttgt aatagattat taaaaagcaa tattatagct aataaatcgt ttgttgacaa
    27781 ttcaaaggta acagaccatc atgcaataat accaacagaa cagaaggtat tcatgagtga
    27841 ttttagtgat aaagagcgaa aaatatataa tcttgtagta aaaagatttt tagcagtact
    27901 atctcctcct tttgaatatg agcagacaac tataagtgca actgtagaag gagaaatatt
    27961 taaggctaag ggaaacaaag taataaattt aggttggaaa gaaagttata aagatattga
    28021 agatgaagat gagtatgaaa gtataccaaa tgttttagaa aaagatgtac ttaaggtcaa
    28081 gggattaaag ataacttcag gaaaaacaaa tccaccacca tacttaaatg agggaacatt
    28141 attgactgct atggaaaaga atggtctagg gacagttgct acaagagcag atataataga
    28201 aaaattattc aattcatttt taatggaaaa gaaaaataaa gatatatata taacatcaaa
    28261 aggaagacaa ttattagatt tagttccagt agacttaaag acaccagaac ttacagcttc
    28321 atgggaaaag aaattattgg atatttcaaa gggaaaactt agtaaaaata cattcataaa
    28381 tgacatgaaa gattattcaa aagatattgt actagaagta aaaaatagtg ataataaatt
    28441 taaacatgat aacttaacta aaaatagatg tccagaatgt ggaaaattta tgttagaggt
    28501 aaatggtaaa aaaggtaaga tgttgatttg tgaagataga gaatgtaata ctagaaaaac
    28561 tatatcacaa gtaaccaatt caagatgtcc taactgtcat aaaaaattag aacttcgtgg
    28621 agaaggtgag gggagaatct tcacttgtag ttgtggatac agagaaaagt tgtcttcttt
    28681 caacaagaga aagcaagaag aaaaacagaa ggcatcaaaa aaagatgtta atcaatattt
    28741 aaaaaatcaa aataaaaatc aagagacatt taataatcca tttgcagaag cattagctaa
    28801 gctaaaaaac aaataatttt aaagttatta ttatacacaa ttataacttt aactgtatat
    28861 tagttatatg tactgatata atatagtgta tagtttaggc atgaaagtag ggctgttaaa
    28921 tggatttaag tggcatattt aaatactatt gtaaagagtg tgaaaataca tggaataatt
    28981 cgagtgttga attatttgag aatatagaaa cgtatagtaa agattcacaa aaaaagaggg
    29041 aaaaagaatt agataaattg ctaaatacaa tatcagttca tttagagagg tatccaagtg
    29101 atgctgtatt gagaaaaatg tgggtaaaaa agggcgaggt tttcttacaa aagacattgg
    29161 aaaaagaaaa tatttttaag ttagaaaaaa tggatgtaga ggatagaaaa aaatttttag
    29221 atataacaaa acagtttatt agagatgcta gaaaatttga tgatgattta cctataggtg
    29281 atattatgca agctatgagg aatgtatgga tttcaaatgc attacaatta ttatttggta
    29341 aagaagtata ttattcaaaa gctaactttg catatagtat gttatatcca tatactgata
    29401 attatttaga caatacaaat atagataaaa atgataagat tttatttaat aactggttag
    29461 aaaaaaggct cctgggagaa cacattaaat ctaaggatta tcatgaaagt aaagtatctc
    29521 aaatgataga ttatattgaa agtgtatacc ctagagaaaa gtttacagaa gtttatgaat
    29581 cgttattatt aatatttaaa agtcaagtaa atagtttaaa acaacatggt aaggaaaatc
    29641 atttgtgtaa agaagattta ttatccattt ctattgaaaa aggaggttca tccgttttag
    29701 tagatggata tttaataagt ggattgatga caaaggaaga aatagagttt tgtataggat
    29761 atggattttt attacaaata tctgatgatt tacaagatat aaaagaagat ttaaaataca
    29821 accataaaac tattattaca gagatgtcaa aagagggtac tttagataaa gttgtaaata
    29881 aactaataaa ttttactatt gagttaatag atagttttaa aattaataat aaaaataaat
    29941 ctgtaataac tatgataaag aatgattgct taatgttaat tttattttct gtagtttata
    30001 atgctgaatt tttttctgta ggatatataa aagaagtaga gaaatttatt ccatatacaa
    30061 tagattattc attagagatt gaagaaaaaa taaaagaaaa atttaaaaat atagatgttt
    30121 taaataatga aaatgaatat aaagaaatga ttgatattat ttgtgcagag tagaaaaaaa
    30181 gggagtgtct tagaatagac tttttagttt atgaggcact ctttttgtat aaaatcaaat
    30241 gtattttcat cattttaata attaaaaaga gcttatccct atttgagaaa gcccttttta
    30301 atttaaataa aaatgtcaag gttaaactat ttaaatgcag taataatccc attatcatgt
    30361 aagtttttta tgattgtagc tgcgataggg aatccaaata atccagctat tccaaatagt
    30421 tgagctccaa caaacataca cattaatgtt attaaaggat ataggccaat ttggtgtcct
    30481 actacctttg gttctaatat ttgtctaaca acggttataa ttatgtatag tattaaaagt
    30541 cctattgcta aattaatatt tccattaatg agtgagataa tcatccaagg tgtcaaaata
    30601 cttcctgtac ccaagactgg caaaatatca acaagtgcta tgatgacaga tatagtaaat
    30661 gcattttcaa cctttaggat agtaagtcca ataagtagtt ctatgaatgt cactgatagt
    30721 agtattgcat aggcttttag tagttttaaa agagcattaa tactgctatt ttttatattt
    30781 attatcataa attgactttt ttctggaaat tgttttaaga taaagtttac tattttttga
    30841 tagtcaaaag taaagaaaaa agaagcaatt aaagtaataa taagttttaa cataaatgca
    30901 ggtgttttac ttgcaatact agcaatagca ttgagtgcat ttgttgaaat agaagctact
    30961 aaagacatca tagattgact tatattatcc caaccaagta ttaatgctag gttaacatta
    31021 ggtgtactag catctatctt tgaaaataaa gtatttagcg ttggttgtat acttgattta
    31081 tatatttcag gaagtctaaa aaatacatca cttacacttg caaatatctt cacaccaaag
    31141 ctaactaata aaaatataca caacccataa aaaattaaaa gtattactat agaaataagt
    31201 gtacgattta aatttgtatt atttgtaata agtcttataa taggtcttaa gatggatgca
    31261 atgataaaac tgattacaaa aggcattaat aatggcaata agaattttaa tacaatatat
    31321 acaatacttg ttattaaaac tacatatgta aatttaatta taaaattctt ttgcttttga
    31381 atatccataa tataaaacct ccaatgtatt tgatattatt ctaaatatgg tcttttttac
    31441 agaaaatata ctactgtata ttgattataa actataaagc ttatgtaaag taaataaatt
    31501 atgtaaaatt taggttaatt ttgtataaag agatactttt atattttaca attaataacc
    31561 aaatactaaa aaatatttta aataaagaac ttaaaattgt gataaaatta atttatagat
    31621 attaaaaaaa gtataatata tggtttttaa gaggtgctaa gatgaaaaat tttagagatt
    31681 taggtgggaa caaaactgag gatggcagaa ctgtaaagaa gggattattt tataggtctg
    31741 caaaattatc aaatctaagt gaaaatgata taaagatttt aaaagagtta aatattaaat
    31801 atatatttga ttatagaagt gatgaagaag ctcgtaaaca tccatcaaca ataatatcaa
    31861 atataaaaaa tataagaata ccagcaatga gagagctaga agaatcagga ggaagttttg
    31921 gttctattga agatatgatt gatggattgt ttgaaaaaga tggtgcattt aatatgttaa
    31981 ataatagtta ctataatttg cctataaata atccgtcata taaaaaatta gtagaactta
    32041 taagagacta ttctaattta ccaatattaa atcattgtac agctggtaag gatagaactg
    32101 gtgtggggag tgctataatt cttatgattt taggggtatc gagagagaat ataatgaaag
    32161 attatctaaa aagtaatgat tttgcagata aagagataga aagatttata gaatataagc
    32221 ctaaatttaa ggacattcca aaagaaaatt tgaaatatat atttggtgta aatgaagagt
    32281 atatgaaaac tgcatttaga agaattgatg aagaatacat tagtgtagaa gcatatttat
    32341 atggagaatt taatttaaat aaagaagaaa taagaaaatt aagaaatcaa tatctagagt
    32401 aaaaggtgag tttatgagtt taaatataac agcaagacag ataaatataa taaaaatatt
    32461 gttaaattca aaagatacaa ttagtggtat tgccttaagt caagagatag gatgttcttc
    32521 aaaaactata caaaatgaaa taaaggatat taataaacaa cttagaaatg gtaaaatttt
    32581 gtcaataaga ggagttggtt ataaactaga aggaagtttt gatgaggtaa atctaaatag
    32641 caatctctat gatgatgtag atagagtaga atatataatc agaaaaatat taaccttaag
    32701 taatgaagaa aaaaatacta taaaacttga agatttagcc gattctatgt atgtaagtgt
    32761 ttcaacagta aaaaatgatt taaaagaagt aaaaagaata ttggaaaagt attcaatatc
    32821 agttaaatct aagcataaac aaggtatatg tgttttggaa agtgaagata agatattaaa
    32881 ttgtatagtt gacttaagca ataagagaga taatcaattg agtttaaatg attttttaaa
    32941 tgatgatata aaggaaagaa aactattaat aaaaaaatta ttattagaca tattaaatga
    33001 aaatggattg gtattaactg atatagaatt taagagtgtg ttaaataata tattagttat
    33061 gttaagcaga cataagtata atgaaaaaga atttatagag aattatatag aaaattatag
    33121 gagcaaaaga agctcaattt tagaaaatga acaaaacaaa gaaattataa taaattcaat
    33181 aaaaacattt tgtaaaaatt taaaattagc tacatcaata gatataagta atgataaggt
    33241 atttgaagag tttttatata agcatattag tagtttatgt aaaaaaataa agttaggtat
    33301 aaatcaatca cctataatgg ctcaagatat aaaaataaaa tatccatttg cttttgaact
    33361 agctaatata gctaaaaaga caatagaaaa agatttgaag atagaaatta atgaagatga
    33421 agttgcaaac atagccctac atataggagg agcagttgaa agagcatctt ataataataa
    33481 agataaggtt ttcaaaacta taatagtttg tacttcaggc ataggcacat caatgttaat
    33541 aaaagctaaa ttagagaata tatttaagga aaaattagaa atactaaaga ttattccttc
    33601 atacttagtt gaatatataa aagttataga tgttgatttt gtaatatcta ctgttcctat
    33661 tgaagtagga gatgtgccag taataaatat atctccaatt ttaagtgaga aagaaattag
    33721 attaattgaa aaatatatag aaacaggaaa tatataccta gatttagata taaaaagcct
    33781 gtttgatagt gaattgtttt ttactgattt ggtgtttaaa aggaaagaag aagttataga
    33841 ttttatggca agtaaacttg tacaaaaggg ctatatagat gaggatatga aaaaatctta
    33901 ctttgagaga gaaaaaatag caacaacaga aatagggaat atggtaacta taccacatgg
    33961 agctattgga aaaatttttg ataataaaat agcaattggt atattaaaga agcctatttc
    34021 ttgggaaata tcagatgttc gtttaataat aatgttagcc cttgataaag ataaaatatt
    34081 agattatgaa gtaatatttt caaaaatata taaaagagta gattctatag caaaagttat
    34141 aagtatatgt gaaaatagta gttttgaaaa atttgtaaat ttatttaatt agatgggtag
    34201 tattgtatat acacctgtaa atttggataa tataaaacta aataagataa aaacgataaa
    34261 tttctctttt aattaagaga aattttttga ctttcaagga tattaatata aagttaagat
    34321 ataaacataa agcaaataaa taaaaaagag gtggcaatat gatttataca gtgacattaa
    34381 atccatcaat agattatata gttaagctag atgagctaaa gacaggaagt acaaatcgtg
    34441 taaaagaaga atacgtttat ccaggaggaa aaggtataaa tgtatctcgc atacttaagg
    34501 aacttggaaa tgataacaca tctttaggtt ttataagtgg ttttactgga gaatatataa
    34561 taagaacatt ggaagaaaaa gaattgaaga cagattttat aaagataaaa agtggttttt
    34621 caagaataaa tgtaaaaata aaggcgttaa aggaaactga gattaatgga caaggtccaa
    34681 atatagatga tgaagacatt gatactttat ataaaaaact tgataagcta aatcaagatg
    34741 atattttaat attggcagga agtataccat ctactttaga tgaaaaacta tacgaaaata
    34801 taatggctag attagaaaaa aagaatataa aagttgtagt agatgcaact aaaaatcttc
    34861 ttcttaatgt tttaaaatac aaaccttttc taattaagcc taataacgac gaattagaag
    34921 aactatttgg tgttaaatta aattcaattg aagacatggt aaaatatgct agaaggttaa
    34981 aggaaatggg agctataaat gtcttggtat caatgggaaa aggtggagca ttgttgatta
    35041 cagaggaaga agaagtgctt ataagtgatg ttccaaaagg aaaagtaaaa aattctgtag
    35101 gagcaggtga ttcaatggta gcaggattta tatctgggta tttgaatact gggaaatatg
    35161 attatgctct taaattggga gcagcttcag gtagtgcaac tgctttttca tatgacttag
    35221 ccaaaagaga atacattgat aaattggtaa atgagatatc tgtaaagaag ttttaaaata
    35281 ttaaaaaata tatagaaagg taattaatat ttatgaaaat tatagattta ttagatgaaa
    35341 agtcaattaa gttaaattta aattcaaaaa ccaaatcaga agcaatagaa gaattagtag
    35401 atttggtcgc aaatagtgga aatttaaatg ataaagaaaa ctacaaaaaa gcaattttgg
    35461 ctcgtgaaga aatgagtaca acaggaattg gagaaggtgt agctatacct catgctaaaa
    35521 attcttcagt tactaaagct tgtatagcag cagcagtgtc aaaagaaggt atagattatg
    35581 aatcgtttga cggaagttta tcaaatctat tttttatgat agctgcacca gacggagcta
    35641 acaatactca tcttgaagta ttatcaagat tatctacaat acttatggat gaagacttta
    35701 gaaataaact tataaattca agctctgaaa aagaatttaa ggaaataata gataaaaagg
    35761 aaagagaaaa attcagtgaa gaatatcaag atgagaaagt tactgaaaaa aatataatag
    35821 atactaaaga gaatgatgct aataagtatc ctaaggtttt agcagtaaca gcatgtccaa
    35881 ctggaatagc acatacattt atggcagctg aaagtttaaa taaaatggca gaaaacaaag
    35941 gtgtatcaat aaaagtagaa actaatggtt cagcaggtgt taaaaataag cttacaaaag
    36001 atgaaataga aaatgcaaca tgtataatag tggcagcaga taaaaatgtt gagatggcta
    36061 gatttaatgg caaaaaagtc ataaaaacta aggtggctga tggtatacac aaagcggaag
    36121 aacttataga caaggctgta aatggagatg ctccaattta ccatggagga gatggaagtc
    36181 acaacgaatc aaatgaagaa agtgaaagtg gatttagaaa agtatacaaa cacttaatga
    36241 atggtgtatc taatatgtta ccatttgtta ttggtggagg gatacttata gcgatagcct
    36301 ttttacttga tgattatact attaaccctt caaactttgg ttcaaataca cctatagcag
    36361 ctttttttaa aggaatagga gataaagctt ttggatttat gttacctgta cttgctggat
    36421 atatagcata ctctatatct gatagaccag cgtttgttgt aggatttgta ggaggtgctc
    36481 tagcaggtga tggtggttca ggatttttag gtgcactact tgcaggtttt atagcaggtt
    36541 atttagtaga agggcttaag aaaatattta gtgtactacc agcttcattg gaaggaataa
    36601 aaccagtatt gttatatcct ttacttggaa cacttttgat gggaattata atgacatttt
    36661 tagtaatacc tccagttaca gcaattaata atgcaatggt tggattttta aatggtttag
    36721 gtggaacttc aaaaatattt ttaggattag tattaggtgg aatgatggct gtggatatgg
    36781 gtggacctgt aaataaagca gcatatgtat ttggagttgc atcacttgaa tcagggcagt
    36841 ttgaaataat ggcagcagta atggctggtg gtatggttcc gccacttgct atagctcttg
    36901 caactacatt ttttaagaat agatttacta aagaagaaag agattctggt aaagttaatt
    36961 atgtaatggg attatcattt gttactgaag gagcgatacc ttttgcagct ggagacccac
    37021 ttcatgttat accagcttgt gttggaggtt cagcagtggc aggagcactt agtatgttgt
    37081 tcaacgcagc tcttcgtgca cctcatggag gagtatttgt tataccagtg gttacccatc
    37141 catttgcata tatattagct atagctgtag gcgctttggt tggaatgatg cttttagcat
    37201 tacttaaaaa accattaaat caagaagtat agcaattaaa ggatattcaa gaacttaaaa
    37261 tatgatgttt tataaaaatt aatatattgc tgaattattt taaaataagg attttatgag
    37321 gctgttatat aacgatttgt aattgttatc ttgacagtct tttattttta tataagtaaa
    37381 ataagtgtgt tttgctttat ttgtatttaa attgttttca agttagaaca taaagaaaat
    37441 tatatattat tt
//
LOCUS       DAMJXI010000036        34781 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.038, whole genome shotgun sequence.
ACCESSION   DAMJXI010000036 DAMJXI010000000
VERSION     DAMJXI010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34781
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.038"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(108..764)
                     /locus_tag="PC465_002274"
     CDS             complement(108..764)
                     /locus_tag="PC465_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2649566.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVVIKRRDLMEKIADVITKKQQEILAEMDKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGAAIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
     gene            complement(819..1448)
                     /locus_tag="PC465_002275"
     CDS             complement(819..1448)
                     /locus_tag="PC465_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDF2649567.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSKHKEIELSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERMNLLNECSLKECDYLSENGAKLFDDIEDTLKLLSK
                     KYKLFIVSNCQAGYIESFLKAHKLEQYFIDFECPGNTGLHKGENNKLIIERNKLINPI
                     YVGDTQGDANSAKFVGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            complement(1579..2220)
                     /locus_tag="PC465_002276"
     CDS             complement(1579..2220)
                     /locus_tag="PC465_002276"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HDF2649568.1"
                     /translation="MKICIVLNGEIEDYEVTRDIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTISVIAI
                     NGDAKGVTLTGLEYPLDNYYMKYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            complement(2229..2900)
                     /locus_tag="PC465_002277"
     CDS             complement(2229..2900)
                     /locus_tag="PC465_002277"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDF2649569.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPVDTIKHVLPDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVAEVVQAGANIIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            complement(2905..3789)
                     /gene="rsgA"
                     /locus_tag="PC465_002278"
     CDS             complement(2905..3789)
                     /gene="rsgA"
                     /locus_tag="PC465_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HDF2649570.1"
                     /translation="MLEGKIIKGISGFYYVDTYNGIYECKARGIFRKQKITPLVGDRV
                     KISIVDEDEKKGILEEIDSRDTELIRPPIANVDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKNIYELSGYKVIPVSNITKLNIDKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLVLEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVTNGEISKERY
                     DSYIQLLHEIRQNNSRRY"
     gene            complement(3887..4624)
                     /locus_tag="PC465_002279"
     CDS             complement(3887..4624)
                     /locus_tag="PC465_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDF2649571.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTILNEKNFSVKLFKANISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITD
                     EDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDALVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            complement(4732..6747)
                     /gene="pknB"
                     /locus_tag="PC465_002280"
     CDS             complement(4732..6747)
                     /gene="pknB"
                     /locus_tag="PC465_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HDF2649572.1"
                     /translation="MGDTILGNRYEIIRKIGDGGMAFVYEAKDRLLNRTVALKVLRPE
                     FVDDDEFLTKFKREAEAVASLSHPNIVNVYDVGEDGKVHYIVMEFVDGKNLKEIIQDE
                     GILDEYTALDITKQIAMALSAAHKKGIIHRDIKPHNILISNEGRVVKVADFGIAKAVS
                     NSTMTNIGSIIGSVHYFSPEQAKGKFVTNNADLYSLGIVLYEMLIGKVPFRGDSPISI
                     ALQHINDDIDFTSEEKVRIPQSVRTTIKKLTEKSSADRYQTAEELIEDIEYIEKNIDL
                     DFIKEYDDFATKKIDEKEINKVVNPTLAKPAPEKVVKPVEVADLDDDEDYYDDFYEED
                     DDEDEEEEEIMRAKKNQRPKSTPSKRTKKKKKKQESPKSRRRLKVIAAVLILILCAQV
                     FLAYKFLFAGGFGNKSLTVPNLVNMTLEEAQSAVEKEGLYLSVKSEEYNSEVDENCII
                     SQTPEGGSTNVKKGDTINVVVSKGSSQASVPNVVGLTLSNAKQLIEENNLKVGTVKYE
                     YSSIYKEGTVLSQSPGAGSSRAQEGDEVNLYVSKGSEKSNTQTPTVPDKKPTTPENNT
                     PTEPGSNSGNSGGNSGGSNSGNSGGNSGNNGSNSGGSNSGNSGGNSGGSNSGDNGGSS
                     GGSNSGDNGGSSGGSNSGDNGDSSGGSNSGDNGGTSSGTGANIGKTE"
     gene            complement(6764..7516)
                     /locus_tag="PC465_002281"
     CDS             complement(6764..7516)
                     /locus_tag="PC465_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HDF2649573.1"
                     /translation="MVYSCASHIGKIRKNNEDYCEGEVIDTEHGPIGIFAIADGMGGH
                     KKGEVASKLAVENIIDFLKENLLQHDNVKIDYIDDILKQAYNNVNSIVHKKSMEDIEF
                     EGMGTTLVTAIVYNNVLYVANVGDSRCYLLTDEKFDKITIDHSVVEELMMAHVITEEE
                     ARRHPQRNRITRAIGTDDMVVVDIFKKEIKKSDIILLATDGLTGFIDDEDIRDLILDY
                     EYERTSNISEELISMANDVSGKDNVSVIVIKV"
     gene            complement(7536..8567)
                     /gene="rlmN"
                     /locus_tag="PC465_002282"
     CDS             complement(7536..8567)
                     /gene="rlmN"
                     /locus_tag="PC465_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HDF2649574.1"
                     /translation="MEKKKIVLKNFTEDELKEFMKTIDEKPFRGSQIFSWIYKGAKTF
                     DDMNNIPKSLRNKLEEVSCIGHIDIELKLESKVDNTKKYLFLLDDGNIIETVMMDYDS
                     RVTVCVSNQVGCRMGCNFCASTMDGLIRNLEPWEILDQVIKIQEDTGKRVSNLVLMGS
                     GEPLDNFENTKQFLKIINEKNGLNIGYRHITLSTCGIVPKMYELADLEIAINLALSLH
                     SPYDEERRKIMPVANAYSIEEILNACRYYIKKTNRRVTFEYSLIKGVNDSEKEAKALA
                     KLLKGMLCHVNLIPINKVEEREYEKPDKAFIYKFRDSLEKNNIPATVRMSMGSDISGA
                     CGQLRRKYK"
     gene            complement(8575..9900)
                     /gene="rsmB"
                     /locus_tag="PC465_002283"
     CDS             complement(8575..9900)
                     /gene="rsmB"
                     /locus_tag="PC465_002283"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HDF2649575.1"
                     /translation="MDAREVGFKVLCDIEKNDNYSNIAINKHFKNLEISDMDRGLATE
                     LIYGVIENKYYLDYIINKLSKIKVKKMSTYVKIFLRMGTYQILFLDSISDYAAVNETV
                     KLSKKYDKKSSGFINAILRNEIRAKETIMDITEEDSVKYLSIKYSYNSWIIKNWIDKF
                     GQEFAEDLLEANNEKPSIYIRTNTLKISREELIEKLSEMGIVCLKVPMVEEAIKVEKM
                     KNIEKNELFKAGLFTIQDISSMIVGKVINPKEGSFILDVCSAPGGKSTHLATLMNNTG
                     QVVARDIFEHKLKLINSTVNRLGLKNVFVERFDASEIDENSISKFDYVLADVPCSGFG
                     IIRRKPEIKYKKEEELKDITSIQKKILENASKYVKVGGTLVYSTCTIQGVENINIVTS
                     FVEENHNFEFVPIDTVNVDLDNQDKGYLKIYPNIHGIDGFFIAKLKRIR"
     gene            complement(9962..10663)
                     /locus_tag="PC465_002284"
     CDS             complement(9962..10663)
                     /locus_tag="PC465_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HDF2649576.1"
                     /translation="MYPVYGGFWGFDPTMVVLIPAILLTIYAQFKVSSTTNKYLRVNT
                     RRGYTGEQTARRVLDSNGLYDVKIEMVRGHLSDHYDPRRKAVRLSEDVYYGTSITSVA
                     VAAHECGHAIQHAKGYAPLQIRSSLVPVVNFASSISWFLIFLGFIMAGPFLKIGILLF
                     SASVLFQIITLPVEFNASSRAIVQLGNLGIIDESESRQSRRVLSAAALTYVAAALVSI
                     LQLLRLLLIAQRRND"
     gene            complement(10732..11484)
                     /locus_tag="PC465_002285"
     CDS             complement(10732..11484)
                     /locus_tag="PC465_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF116 domain-containing protein"
                     /protein_id="HDF2649577.1"
                     /translation="MTDIKKYLTSVGILILILGILIGVVNFFIISLTQIFSLMINIII
                     ISLILIILCSTAVTYRVIKGKYVNSNIMKINFNIVSGLFPIISFIASSFGMSKSDIRR
                     IYIKLNNEYIYSNKYNFNPEDIIILIPHCIQENSCKLKVTNDIDNCKECGRCNIGELI
                     KLKEKTNVKIFVATGGTLARKIIMDTKPKAVVAVACERDLTSGIQDIKKIPVLGVFNK
                     RPNGPCVNTNVDMMDIEKAIGFLTGKNILVCN"
     gene            complement(11494..12423)
                     /locus_tag="PC465_002286"
     CDS             complement(11494..12423)
                     /locus_tag="PC465_002286"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HDF2649578.1"
                     /translation="MKIVFMGTPDIAVPCLQKIIDEKYEILGVVTQPDKPKGRGKKLG
                     MSPVKELAIENNIPVYQPVKARDKEFIDKIKSLNPDVIVVVAFGQILPKEILEIPKLG
                     CINVHVSLLPKYRGAAPINWVIINGEEKTGVTTMYMDEGLDTGDMILKTEVNLDENIT
                     AGELHDKMMNIGAETLKETLRLIEEGNAPREVQNHEEFSYAPIMNKSLGNIDFSKSAR
                     EIHNLVRGVNPWPSAYTTYNDVIMKVWKTKVLDEKSTKDVGTIIDVSKDGIKVSTIDN
                     VLLIEEIQMPNKKRMLVGEYIKGNTIETGLVLG"
     gene            complement(12438..12878)
                     /gene="def"
                     /locus_tag="PC465_002287"
     CDS             complement(12438..12878)
                     /gene="def"
                     /locus_tag="PC465_002287"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDF2649579.1"
                     /translation="MALRQIVQIGEPVLRKKSKKVEKIDEKIIQLLDDMAETMYDADG
                     VGLAAPQVGILKRVVVIDIGEDLIELINPEIIETSGEQIDEEGCLSVVGEAGNVRRPN
                     YVKVRALNRNGETIELEGEELLARAFCHEIDHLDGILFVDKIEK"
     gene            complement(12896..15421)
                     /gene="priA"
                     /locus_tag="PC465_002288"
     CDS             complement(12896..15421)
                     /gene="priA"
                     /locus_tag="PC465_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HDF2649580.1"
                     /translation="MNNILNLSRGFIMKKYAKVIVRSNTIYTDNLFTYQIPVFLSDVI
                     KIGHRILVPFGKGNKPTEAFVFQFTDSLDEKIKIKEIIDILDENPIFRKEDLELVYWM
                     KNRYLCTYIECINLIYPKGYKLNNYKVVLLGESLSGLNDIELKEKISTLSDKNREIVE
                     KVIDSKGKIKVDKLKYIPNLNSSLYTMNKNGIIKLCWEYKNHKNEKKVCYISLSLESD
                     KIDDYIEQNKINVGSKQKEILSFLKNNENVEINDLLDLLNASKQSINSLSKKKLITLE
                     FKDYYREPKSIYKSVLKSIKLNNEQQEAVDEIKSNMFVDDKKPYLIHGVTGSGKTEVY
                     MEIIEFALNQGLDSIFLVPEIALTPQTIDRLKSRFGDLVGVFHSKLSEGEKHDVYKAV
                     KAGKVRVLIGARSALFAPFNSLGLIIIDECHESSYKSEKNPKFNAIEVARFMALKNNI
                     TLILGSATPSIEEYYRAKSGEYKLINIKSRANDKPLPNIEVVDMKDELDKGNRSIFSL
                     KLQKEIRYAIEENNQVILFLNRRGYANFVSCRKCGYVFQCENCDISLTYHKKSNTGRC
                     HYCGYEKEIPKECPECKSTYVKPFGVGTQKIEEELKYIFPDIKTLRMDKDTTSKKGAL
                     DEILNKFKDKEADVLIGTQMLSKGLDFENVTLVGILSADMILNFPDFKSFETTFQLIT
                     QVSGRAGRADKEGKVVLQTYDTEHYAIKHAIEYDYEGFYEDEIKIRKAFGYSPFNNML
                     SVVVSGEDERLVIKNIKNMHASLIYLLEKRGINDLGFILGPNPCSISKINQNYRWQIL
                     FKDENIEINLLKGIIKYICITKRDLIFDKNINVSIDINPNSVL"
     gene            complement(15660..16859)
                     /gene="coaBC"
                     /locus_tag="PC465_002289"
     CDS             complement(15660..16859)
                     /gene="coaBC"
                     /locus_tag="PC465_002289"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HDF2649581.1"
                     /translation="MLKDKTVVIGISGGIAAYKACDVVSKLKKLNANIHVIMTKSATE
                     FVKPLTFQSLSQNYVVEDMFEEPKTWEVEHISLAKKADLFLIVPASANVIGKIANGIA
                     DDMLTTTVMATKAQVLIAPAMNTNMYENPIVQKNIQTLKSFGYKFIEPESGRLACGDI
                     GTGKLANPDIIVEEVLTNLTKEQDLKGQSMIVTAGPTVESIDPVRYLTNRSSGKMGYS
                     IAREAIARGADVTLISGPTNLSIPQNLKKFVQIESAQDLYEAVVSNLSENKIVIQSAA
                     VADYKPKTYSDKKIKKKNDDLSIELSRNYDIAYEIGKIKEDKILIGFAAETNDLIEHA
                     KGKIKKKNLDFIVANDLTKEGAGFRADTNIVKIIDVEGNITEYPKMKKEEVANVILDK
                     VKALLEK"
     gene            complement(16864..17130)
                     /locus_tag="PC465_002290"
     CDS             complement(16864..17130)
                     /locus_tag="PC465_002290"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HDF2649582.1"
                     /translation="MLKPSINEVLEKIDNRYYLVGTVSKRARKLIDGEEPYVSNKTKE
                     KPVCVATKEVASGKITYRLLTEEEIEIEEARHHAEQHQQISEEE"
     gene            complement(17133..17750)
                     /gene="gmk"
                     /locus_tag="PC465_002291"
     CDS             complement(17133..17750)
                     /gene="gmk"
                     /locus_tag="PC465_002291"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HDF2649583.1"
                     /translation="MFVKKGLLLVVSGPSGAGKGTICKELLKENDTIKLSVSATTRKP
                     RTGEVDGVNYFFISKEKFEEMIEKGEFLEYAQIYDNFYGTPKAAIMECLEKGQDVLLE
                     IEMQGAKQIKEVCPEGVFIFVLPPSLEELKNRIVGRGTETEAEIEKRFSCAYEEIKMI
                     KDYDYFIFNEDVKTSAKEIEGIISSEKNKVSRYKNIIIEKFKEEL"
     gene            complement(17780..18661)
                     /locus_tag="PC465_002292"
     CDS             complement(17780..18661)
                     /locus_tag="PC465_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HDF2649584.1"
                     /translation="MAISMTGFGRGEYKDDNYYFLVECKTINHKYSDINIRLPRKISF
                     LEDKVRNLVKNYVKRGRVDLYIKFDLLGKEDVNLNFDEGLASQYIDILKEIKNKFDII
                     DDISVMNVAKFPDIVKIEEKEEDEDLLWSMLNQAVEDALIKLREMRSEEGKKLAEDIA
                     MRCDLLKNHIEEIEKYSSSVVEDYREKLNLRISELLDDPSIIDENRLAQEVAIYADKS
                     SITEEIVRFKSHIGQLKNTIFKDDSIGRKIDFLIQEMNRETNTIGSKSSDINITNLVV
                     EVKSELEKIREQIQNIE"
     gene            complement(18665..19495)
                     /locus_tag="PC465_002293"
     CDS             complement(18665..19495)
                     /locus_tag="PC465_002293"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HDF2649585.1"
                     /translation="MKFWKLHGIGNDFIAIDGRFDQINPSDYTALAKKVCHRRFSVGA
                     DGLLVVKDSKVADVEMVYYNSDGSRAAMCGNGLRCFCKFVYDNCIVKKESFTVDTLDG
                     IKDIKINLTNREINSIRVNMGKGSFIAKDVPVLTNKERFVQESIKVLDRELKVTSMLM
                     GVPHTVVIVDELDVDDVCKYGKEIENNKIFPEKTNVNFVKVEDKYNIHVYTWERGCGY
                     TLGCGTGMTASAIVCNLLNMVESSVNVTSQGGTVKIDVGDFSYMTGPAVKICEGILEV
                     "
     gene            complement(19782..20816)
                     /gene="ltaE"
                     /locus_tag="PC465_002294"
     CDS             complement(19782..20816)
                     /gene="ltaE"
                     /locus_tag="PC465_002294"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HDF2649586.1"
                     /translation="MRFIDLRSDTVTMPTDEMREAMAKAPVGDSIFRDDPTVNKLEEL
                     AAAKVGKEDAIFLPSGTFGNQLALFTHCLRGQEIIIGKGYHIVTHEVGAPAVIAGVQL
                     RTIDEDESGALNPELVEKAIRRDDIHEPQTGLICVENAYSGGTVVSLDNLREIKKIAE
                     KHNLPVHLDGARLFNAALTLGVEAKEIAKCCDSVMFCVSKGLAAPMGSILAGSKEFIA
                     KARRKQKVMGGGMRQVGIVAAAGIIAIEKMTLRLNEDHENAKYLACELNKIDGIEVNN
                     VNPDISMVFFKMSEDIIKEDVLIKEFFERNIKINKMENGEYRFVTHVDITKEDLDYVL
                     KTLKELIGVC"
     gene            21112..22887
                     /locus_tag="PC465_002295"
     CDS             21112..22887
                     /locus_tag="PC465_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HDF2649587.1"
                     /translation="MALDGLVIHSIVDELSSKLTGGKIDKIHQPEDDEVIFNIRNNKE
                     NFRLVLSASASNPRVYLTSNYQKENPLKAPMFCMLLRKYIQGGNIVEISQIGFERIIK
                     ISVESLDELKEKTVKNIMIEIMGRHSNIIITHGEENKIIDSIKRVPFSISRVRQVLPG
                     HDYSLPPEQNKLNPLDDISKDLFIKNLEELEGPIFKSIYSRFLGISPIIAKEICYRAG
                     VNQNAIIKDISDEQFDSLHKVFCNLFNDINSNKYSPCIIIDKKVDKVVDFSCINLTLF
                     SDLSYINKDSMSRILEDFYRTKDIKDRINQRSSDLKKSISVKLDRLYNKLKKQEEELS
                     ESENADIYKIKGELITSYIYMVEKGMESIEVANFYDENCNDVTIELNKNLTPSENAQK
                     YFKKYNKMKHAKVEISHQISLNKEEIDYLENIILSIENCENLAELQDIKEELAKVGYI
                     KTQKKNSKKDTIPSTKPHEFVSSDGFKILVGKNNKQNDYLTLRLADNDDLWMHTKNIP
                     GSHVIIKCAGKEVPDNTVFEGAMLAAFFSKSKLSSQVPVDYTKRKNVKKPSGSKPGMV
                     IYETNSTIYVTPEEETVAKLKVKSE"
     gene            complement(23102..24754)
                     /locus_tag="PC465_002296"
     CDS             complement(23102..24754)
                     /locus_tag="PC465_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2649588.1"
                     /translation="MLLVKVENLKKYYADKLILDIDKLEILENDKIGLVGSNGQGKTT
                     LLKAILGEIEIDEGYTYLTESYSYISQSENNIETCGHSKEKSLLNAPDKFEEHLSGGE
                     KVKLKIADALSNKKNIIIADEPTSNLDKKSIGVLEDMFKRHEGALLLISHDRRFLDEL
                     CTTILELEDGKLKAYKGNYTDYLMQKDEEVKRADFEYQEYVKEKKRLEKALLYKKALS
                     EGIRKTPKRMGNSEARLHKMGGQTNKKKLDSNVKAIKSRIDKLEVKNKPKVSKEMNIK
                     IQDGMEIISKNLVEIKDMTLKLENKLLLDNVSFKIKRGKKIALLGDNGCGKSTLIKEI
                     LADKNDNIKINNKVKVGYFDQNQSLLDEKKSVLYNTKVNSSFDESFIRINLSLFGFKG
                     DDVYKKVKVLSGGEKVKIALCKIILEDNNFLVFDEPTNYLDIKSMEALEKALINTDKT
                     MLIVSHDRVFVSHICNYIIEIKDAKIREFDCNYDEYIISRNKKTPSRENQIKKENLLV
                     LENRLTTVISMLSIEKDNLKKELYESEYNELLKQITKLKNSF"
     gene            complement(25053..26264)
                     /locus_tag="PC465_002297"
     CDS             complement(25053..26264)
                     /locus_tag="PC465_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HDF2649589.1"
                     /translation="MKKTIMSLQHLLAMFGATVLVPILTGFNPSVAIFCAGVGTLIFH
                     FCTEGKVPAFLGSSFAFIPVILAAKEAYGGDLAYAQGGIIVAGLIYIIMSIIVKVVGV
                     NKIKLYFPAQVTGAMIVVIGLNLLPTAFSMASANFVIAFITLAIAILTNKFGRGFIKQ
                     LGILIAVFSGYIICLILRLVDITTITEASLFAIPNFTVPKFSLGAIVIISPVVLAVFM
                     EHIGDMTTNGAVVGKNFIENPGLNRTLLGDGFATIVAGCLGGPANTTYGENTAVLAIT
                     KNYDPSILRRTAIFAILLACVGKFGGFLQSIPGSVMGGISIMLFSMITYVGLKTIRDS
                     SCVESKINILIIAVILLIGLGTTYLSNKGISVGIPITSTVKITGLSLAAIVGIVLNRI
                     LNNQDFKVEEE"
     gene            complement(26549..27082)
                     /gene="pyrR"
                     /locus_tag="PC465_002298"
     CDS             complement(26549..27082)
                     /gene="pyrR"
                     /locus_tag="PC465_002298"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HDF2649590.1"
                     /translation="MVEKAQLMDEKAIARAITRISHEIIERNKGVENLVLVGIKTRGV
                     PIANRISKKIEQIEGTKVDTGDIDITLYRDDLEKIHVEPVVKGTYLDFNVNDKTVVLV
                     DDVLYTGRTVRASLDAIIDIGRPKSIQLAVLVDRGHRELPIRADYVGKNVPTSRHEII
                     SVSLLEIDGEDSVTIKE"
     gene            complement(27442..28389)
                     /locus_tag="PC465_002299"
     CDS             complement(27442..28389)
                     /locus_tag="PC465_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDF2649591.1"
                     /translation="MFYFLKVKVGDIMDEVKEFLVLEEEEEVRLDIYLAEQLGDMSRS
                     YIQKIIKDGKVKVNNKVEKARYLVKEEDNIVIEIPEPKVLEVLPQDIPIDIVYEDDDV
                     LIINKPQDMVVHPAPGNYENTLVNGILYHCKDKLSSINGVIRPGIVHRIDKDTSGLLM
                     IAKNNYAHNFLAEQLKEHTITREYEFICYGVVKEDKITVDKPIGRNPKDRLKMAVVKD
                     GKNAITHFEVVERFDKFTHMRARLETGRTHQIRVHALSINHPLLGDYVYGPKETKFKL
                     KGQTLHAKKLGFIHPTTKEYIEFNSELPEYFKEVIKKIK"
     gene            complement(28358..28804)
                     /gene="lspA"
                     /locus_tag="PC465_002300"
     CDS             complement(28358..28804)
                     /gene="lspA"
                     /locus_tag="PC465_002300"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HDF2649592.1"
                     /translation="MLYILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVE
                     NRGAAFGLLQNNQWIFIIVALLATVFGLYYLNTRKVHIFGRLGIILIISGALGNLIDR
                     VRLGFVVDYFDFRIIWEYVFNIADVFVVVGTVFLCIYVLFFESKSR"
     gene            complement(29111..29890)
                     /locus_tag="PC465_002301"
     CDS             complement(29111..29890)
                     /locus_tag="PC465_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2649593.1"
                     /translation="MKKIIWGICICLLSIVGVYTYSHNTHNQDSSKEAYSLNDNIKDD
                     YEDVIIKKGNEDEKILALTFDDGPDEDFTPQVLDILKKNDVKATFFVVGEKVEYNKEL
                     LKRQYDGGHEIGNHTFTHINVAKNSYSSVEKEITDTQNIIKSVIGVEPKIFRPPYRAM
                     SKSVCDIIVSKGMNIILWSNLDPRDWSNPGVDAIINTILTKVQNGNIILLHDYNTKRN
                     DKSQTIQALEVVIPKLKERGYKFVTVSELIQHLDKNKQVQK"
     gene            complement(29945..30427)
                     /locus_tag="PC465_002302"
     CDS             complement(29945..30427)
                     /locus_tag="PC465_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HDF2649594.1"
                     /translation="MDTKKYKDKLLKERENLTNLVEDMKDNTLFGDTTKHTSEKYSSG
                     ELSSYDNHIGDMGTDLYMQNMQNSLINHEEGRLYQIDLALSKIENGTYGICDLCHNQI
                     DLERLDILPDTSLCNDCANKENNLLGDAMQNPDVEDSNFYSEDLTNLTDLNKNGILRD
                     "
     gene            complement(30693..32114)
                     /locus_tag="PC465_002303"
     CDS             complement(30693..32114)
                     /locus_tag="PC465_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HDF2649595.1"
                     /translation="MVSFLGSIVVLIVGYFVYGTFVEKVFGTNDKNQTPAIACRDGVD
                     YVPMKWKRIFLIQFLNIAGLGPIFGAIQGALFGPSAFLWIVFGTIFAGGVHDFASGYL
                     SMKNKGTSASELVGLYLGNGAKIAMRIFSVILLVLVGVVFVTGPAGLLKTLTGVNAQI
                     WVGVIILYYIMATVLPIDKLIGKIYPLFGAALLIMAVGVAGGLIIKGYNIPNINLQNM
                     NPNGTPLFPYLFITIACGAISGFHATQSPLMARCVEKESEARPVFYGSMVAEGIIALV
                     WAAAAMSYFHGIPQLNVIFNDGGAATVVNTVSVGLMGPIGGALAILGVVACPITSGDT
                     AFRSARLTIADAMNYNQDAVKNRFLIALPLFAVGVALTFIDFNIIWRYFSWANQTLAM
                     IMLWTGSAYLVKANKNHYITTLPALFMTVVTFSYIMQAKEGFRLPVNISNGIGVIVAI
                     ILGLLFFKKAKHIKEQNNHKLAS"
     gene            complement(32260..33030)
                     /locus_tag="PC465_002304"
     CDS             complement(32260..33030)
                     /locus_tag="PC465_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2649596.1"
                     /translation="MRAIIVEDEFPARKELRYFIENKSGIEVVSEFTNGIEVLDFIQE
                     NKIDVIFLDINIPHLDGMLLAKTLNQFKSRPKIVFITAYESYAVDAFSLDVFDYILKP
                     YSEERIISMLNKLEKSEMSDIELSNVNSNLYKYKKEAVNQEIEEITHKISLWKGDKLV
                     VIDIDDIYYCEANERQTFIYTEKEKFILKEGISEVENLINDKTFFRTHRSYIVNLTKV
                     KEIIPWFNNTYILKLKNSDYEVTVSRSKVKEFRLLMHI"
     gene            complement(33035..34237)
                     /locus_tag="PC465_002305"
     CDS             complement(33035..34237)
                     /locus_tag="PC465_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF2649597.1"
                     /translation="MKTSILIALIEKTSLIVVLFLLITKLKIFKQIFQKEEYSFNDLV
                     CIALVFTFLAIFGTYSGINYMGSIVNTRIISIVSGGILFGPMVGITAGVFSGIHRYFM
                     DIGGITSVPCLLSSILAGVLSGFLYKRIPKQHRVMYGILVGMISESFTILLIYLISYP
                     HSLAIQIIGGIYLPLIVGQIGIGFVISIVEGIEKDKKDIEARNKAEIKALQRQINPHF
                     LFNSLNTIASFIRFSPDKARELIINLSTYLRYNLEYSDNLIDINKEIEQVKSFVEIEK
                     ARFGELLTVSYDIEDVNIKIPSLIIQPLVENAIIHGILESGRAGVVKISIKKLPYSLE
                     NTVRISIEDNGIGISEEIINNVYQDNMPENKIGLYNVHLRLKLMYGRGLNIRRIDNGT
                     LIVFYVKE"
BASE COUNT        11078 a         6372 c         3494 g        13837 t
ORIGIN      
        1 tgaaatataa aattaatatc aataaaacct actttttaat tttttaaata tttattttta
       61 atttattttg tttttaattt acttcgattt taaaatgtcc ttgactttta ttttataaat
      121 gtacatattt cttctactgg ttttttagat ggactcttca aattgtcctc tggcactcca
      181 agagctaaca ttgcacctaa aaaatactct cccttttcaa aaccagtttc tgcttctaaa
      241 acagcttcta tctcatctgc tgcatagttt tgacttgtca accaacaaga accatatcca
      301 agttcaattg ctgatagtgt aaagttttca attgcagcac ctagactctg catacctgga
      361 tttcttataa ataatttatc tatagtctcc ttaggtgcat ctataagctc taattcataa
      421 tatcctgatg ggttatatac ctttgtaaaa actaatacta aaactggagc ttttaaataa
      481 aatagtgtaa agtttttaac aaattttcta aatctattag ccttatccac tgatacttta
      541 tccatttctg caagtatttc ttgttgcttt ttagttatca catctgctat cttttccatt
      601 aaatcacggc gttttataac aacaaaatgc cagttttgaa tattcttgcc tgatggtgct
      661 gcacctgctg cttttatcat ttttaaaata tcttcatctg atacatcttg atttttaaac
      721 tttcttacac tttgtctttt aaaaatagta tcttgtaatt ccatttttaa atccccccat
      781 aactttttta ttattttaat ataattttta aactcatctt attttaatat atcatgttct
      841 aacaaatctt taaatgagtc tataaaataa tcatatacat ctacattccc aaacccatat
      901 ttggcatata taaaaggtat acctacaaac ttagcactat ttgcatcacc ttgcgtatca
      961 ccaacataga ttggatttat taatttattt ctttcaatta taagtttatt attttctcct
     1021 ttatgcaaac cagtattacc aggacattca aaatctataa aatactgttc tagtttatgt
     1081 gcttttaaaa aagattctat atatccagct tgacaattac ttactataaa taatttatat
     1141 tttttagata gtaatttaag agtatcttct atatcatcaa ataatttagc tccattttca
     1201 gataaatagt cacattcttt caaagaacat tcattcaata aattcattct ttcttcttca
     1261 cttaaatttg gaaataaacg atttgctatt tcctcaaaag aaagccccat aagacttcta
     1321 aataaatctt ttgtgacact taattctatt tccttatgtt tacttaaaac atcctgccag
     1381 actttgcata cttcttcagt tgaatcccac aatgttccat ctaaatcaaa aataatacta
     1441 tctaccacaa aaaatccccc ttatgtcaaa gtttattata tatttataat tatatactaa
     1501 aaagcagata caatcataaa tatattttac ttgattgtat ctgctctaca atataaaacc
     1561 aattgtcaaa atcaaatttt ataaatttct aactacaagt acacagcctt gctctacttt
     1621 aatcttacaa gaattactca acataacatt tgatattcca ataggtacag agtatttcat
     1681 ataataatta tcgagagggt attctaagcc agtaagtgtt acacccttag catcaccatt
     1741 tatagctatt acagaaatag tgtcccctgg gtttccatac aatgaaattt cctcattttc
     1801 aactatatac atctcttctt tatcagaaag tatcctagaa tatataccat cttcttttaa
     1861 ataatataat agctttatat ttgcaagagt gtggtcaatc cttcccccta aagcaccaaa
     1921 aaaatcaata tgatttgctt taagtgtctt agctaaaaaa agacaaagct ctgtatcagt
     1981 ctcatctttt ttagatggaa atttttcaaa tttaacacct ttatttttat agaaatttat
     2041 cttttcttct tctactgaat ctaaatctcc taatatataa tctggcatta tttccatttt
     2101 ataagtgtga tttgcccctc catctgcaca tattatgcag tcataacatt ccttaattat
     2161 aatatctctt gtaacttcgt aatcttcaat ttcgccattt aaaacaatac agattttcat
     2221 tattaaattt aaactaattc ttcaagagaa gcattctttc taaataaatt aactgtttct
     2281 tgaatgtcat cacttccaaa tattgcagaa cctgctacta ttatattagc tcctgcttgt
     2341 acaacttcgg ctacgttttt agggcttata ccaccatcaa cttctatatc aatgtttaat
     2401 ccttgactat ctataatagc ttttaactct ttaatcttat ctaaaacaca aggaataaat
     2461 gattgtcctc caaatccagg gttaacagac attaataata ccatatctaa atcaggtagt
     2521 acatgtttaa tcgtatctac tggtgtagct ggattaagta ctacaccagc ttttattcca
     2581 tgtgatttta tattttgtat agttctatgt agatgaacac aagcctcctg gtgaacagtt
     2641 attatatcac atcctgcttt tacaaattct tcaatatact ggtctggatt ttctatcata
     2701 agatgagcat caaataccat atttatattt tctttcttta aacttttgac tacaagtggt
     2761 cctaatgtaa tgtttggtac aaagtgtcca tccattacat cgatatgaag atattcacat
     2821 cctgcacttt ctacttttct tacatcttct aataattttg caaaatctgc tgataatatt
     2881 gatggtgcta atttaatcat gtttctaata cctcctacta ttattttgtc ttatttcatg
     2941 tagcagctgt atataactat catatctttc tttagatatt tctccatttg taacagcttc
     3001 ttttatagca caattaggtt cattttcatg aatacacttt gaaccaaact tacaatcatt
     3061 aaatttatca aattctataa aataatcttt aagttcaact tcctctatat cttcaaggac
     3121 aagggaacta aaacctggtg tatctgcaac cattccacca aattctaatt ttaaaagttc
     3181 agcgtgacga gtagtatgtt ttcccctttt tattttatca cttacaactc ctgtttgaag
     3241 tttaaaattt tcatctattt catttaataa gcttgatttt ccaactccag atggtcctgc
     3301 aaacactact acattttctt ttaattcttc ttttacttta tctatattta acttagtaat
     3361 attacttaca ggaatgactt tatagccact aagttcatat atatttttaa cagtttctaa
     3421 tgtatcatta tcatctaaat ctgcttttgt aaggattatt acagtttcta aattttcttt
     3481 ttctgccaaa actataaatc tatctaaaag agataagttt ggtttaggat tttttattgc
     3541 gaatactatt aatgctttat ctacatttgc aataggaggt cttataagtt ctgtatctct
     3601 actgtcgatt tcttctaaga tacccttttt ttcatcttca tcaacaatgc ttattttgac
     3661 tctatcacca accaaaggtg ttattttctg ctttctaaat atccctctag ccttacattc
     3721 ataaatacca ttataagtat ctacataata aaatccacta atccccttta taatttttcc
     3781 ttctagcatc aaatgcctcc ctttataaaa tttatataaa cacatactgt ttatgagtag
     3841 tatatcgtgt tattctttcc tatttttata taataccaca ttttttttaa ataacaaatc
     3901 ctccgtttgg actaattacc tgaccagtga taaaatttga tttgtctgat gccaagaaaa
     3961 tagcacaatt tgctatatct tctggagttc ctagcctcat tagaggggtt tcttccacaa
     4021 gagcgtctat atcttcctca ttatatccag ataacatgtc agtattaatg acacctggag
     4081 ctatgctatt tactctaata tttgatggtc ctacttcttt agctaatgcc tttgtcatac
     4141 ctattatgcc tgcttttgtt atagaataat gcacttcaca agaggcacct gatatacccc
     4201 agattgaaga tatattaatt atatttcctt ttttttctga tatcatgtat tttaaagcaa
     4261 cttgtgaaca ataaaagctt ccttttaaat taatattcat catattatcc caatcttcat
     4321 cagttatatc tgtaaacaac ttatcttgac ttacaccagc attgtttaca agtacatcca
     4381 atcctccaaa ttcttttata caataatcta ccatatcctc tacatcttct ctatttgaaa
     4441 tattagcctt aaaaagtttt acagaaaaat ttttttcatt taatatagtg tacaactctt
     4501 tagcttcatt ttctgactta ttaaaattta ctaatacatt gtaaccttct tttgcaaaag
     4561 ctttagacat agctttacca atccctctag ctcctcctgt aattaaaact gttttcttct
     4621 tcataaatac ttttctcctt atattataac caattcagta ttttatacaa aacaaactgc
     4681 cctttaaaga aaatattttc tataaaagga cagctcttat tttattaata tttattctgt
     4741 tttaccaatg tttgcgccag ttcctgatga agttcctcca ttatctcctg agtttgagcc
     4801 tcctgaacta tctccattgt ctcctgagtt tgaacctcct gaacttcctc cattgtctcc
     4861 tgagtttgag cctcctgaac ttcctccatt atctcctgag tttgaacctc ctgagtttcc
     4921 accactattt cctgagtttg aacctcctga gttacttcca ttattgcctg agtttccacc
     4981 actatttcct gaatttgagc ctcctgaatt tccaccactg tttcctgagt ttgaaccagg
     5041 ttctgttggt gtattattct ctggtgttgt tggtttttta tctggtactg ttggagtctg
     5101 tgtatttgat ttttctgaac ctttgcttac atataggttt acctcatcac cttcctgagc
     5161 tcttgatgag ccagcacctg gactctgact taaaactgta ccttctttat atattgagct
     5221 gtattcatac ttaacagttc ccacttttaa gttattttct tcaataagtt gttttgcatt
     5281 actcaaagta agtcccacta cattaggaac agatgcctga cttgaacctt tacttacgac
     5341 aacatttata gtatcaccct ttttgacatt tgtacttcca ccttcaggtg tctgtgatat
     5401 tatacaattt tcatcaactt cactattata ctcttcactt tttacactca ggtataatcc
     5461 ttctttttca acagcacttt gagcttcttc taatgtcata tttacaagat taggaacagt
     5521 caaagattta ttgccaaacc ctccagcaaa taaaaactta tatgctaaga atacttgagc
     5581 acacaatatc agtatcaaaa cagccgcaat tacttttaat cttcttctag attttgggct
     5641 ttcctgtttt ttcttctttt tcttagttct cttacttgga gtactcttag gtctctgatt
     5701 ctttttagct ctcattatct cttcctcttc ttcatcttca tcatcatctt cttcataaaa
     5761 atcatcatag taatcttcat catcatccaa atcagctact tcaacaggct taaccacttt
     5821 ttcaggagct ggttttgcaa gtgttggatt tacaacttta ttaatttcct tttcatcaat
     5881 tttcttagtt gcaaaatcat catattcttt tataaaatct aaatcaatat ttttttctat
     5941 atactctata tcttctatca attcttcagc agtttgatat ctatctgcac tagatttttc
     6001 tgtaagcttt tttattgtag ttcttacact ttgaggaatc ctaacttttt cttctgatgt
     6061 aaagtctata tcatcattaa tgtgttgaag tgctatagaa attggactat ctcccctaaa
     6121 tggaactttt cctatcaaca tttcatataa aactatacct agagaataca ggtcagcatt
     6181 attagttaca aatttacctt tagcttgctc tggtgaaaaa taatgcactg aacctattat
     6241 actaccaata ttagtcattg ttgaatttga aacagctttg gctataccaa aatcagccac
     6301 ttttactact cttccttcat ttgatatgag aatattatga ggttttatat ctctatgtat
     6361 aatccccttt ttgtgcgctg cactaagtgc catagctatt tgttttgtta tatctaatgc
     6421 agtatattca tctaatatac cttcatcttg tataatctct tttagattct tcccatctac
     6481 aaactccatt acaatgtagt gaacttttcc atcttcacca acatcataaa catttactat
     6541 atttggatgt gaaagacttg ctactgcttc tgcctctctt ttaaactttg ttagaaattc
     6601 atcatcatct acaaattcag gtctaagtac tttaagtgca acagtcctgt ttaataatct
     6661 gtctttagcc tcatatacaa aggccattcc tccatcacca atcttcctga tgatttcata
     6721 tcgatttcct aaaattgtat ctcccacaat atcaccgtcc taattatact tttatcacta
     6781 taaccgaaac attatcttta ccagaaacat cattggccat acttatcaat tcttcactta
     6841 tattactagt tctctcatat tcataatcta atattaaatc tcttatatct tcatcatcaa
     6901 taaacccagt taatccatct gtcgcaagaa gtattatatc actttttttg atttctttct
     6961 taaaaatatc tacaacaacc atatcatctg ttccaattgc tctagttatt ctattcctct
     7021 gtggatgtct tcttgcctct tcttctgtaa tgacatgggc catcataagt tcttcaacca
     7081 cggaatggtc tatagttatt ttatcaaatt tttcatctgt taacaaataa catctgctat
     7141 ctccaacatt tgccacatat aagacattat tatacactat agccgtaact aatgtagttc
     7201 ccattccttc aaattctata tcttccatag attttttgtg cacaattgag tttacattat
     7261 tataagcctg ttttaatata tcatctatat agtctatttt tacattatca tgttgtaata
     7321 agttttcctt tagaaaatca attatatttt ctactgctaa tttactggcg acttcacctt
     7381 ttttatgtcc acccattcca tcagctatgg caaatattcc tattggacca tgttctgtat
     7441 ctataacttc tccctcacaa tagtcttcat tgttttttct tatttttcct atatgggagg
     7501 cacaactata aaccatacga cttcctcctt acaaattact tgtattttct tctcaattgc
     7561 ccacaagctc cactaatatc agaacccata gacatcctaa ctgtggcagg tatattgttc
     7621 ttctccaaac tatccctaaa tttataaata aatgctttat ctggcttttc atattctctt
     7681 tcttcaactt tatttattgg aattaaattt acatgacata gcataccttt taggagctta
     7741 gctaatgcct ttgcttcttt ttctgagtca tttacccctt ttataagaga atattcaaat
     7801 gtaacccttc tatttgtctt ttttatataa tatctacatg cattcaatat ttcttcaata
     7861 gaataagcat ttgctacagg cataattttt cttcgttctt catcatatgg tgaatgaagt
     7921 gataaagcta aatttatagc tatttctaag tctgccaact catacatttt aggtactatt
     7981 ccacaagttg aaagagttat atgtctatac cctatattaa gaccattttt ttcgttaatt
     8041 atttttaaaa attgttttgt attttcaaag ttatcaagtg gctcaccact ccccatcaat
     8101 acaagatttg ataccctctt accagtatct tcttgaattt taataacttg gtctaaaatt
     8161 tcccatggct ctaagtttct aattaatcca tccattgtag atgcacaaaa attacatccc
     8221 atcctacaac ctacttggtt agaaacacag acagtaactc tactatcata atccatcatc
     8281 acagtttcta ttatatttcc atcatctaat aaaaacaaat atttttttgt attatctacc
     8341 ttagattcta actttaattc tatatctata tgccctatac atgaaacctc ttctaattta
     8401 tttctcaaac tttttggtat attgttcata tcatcaaaag tttttgcacc cttatatatc
     8461 caagagaata tttgacttcc tctaaagggc ttttcatcta tagttttcat aaattcttta
     8521 agttcatctt cagtaaaatt ttttaatact atctttttct tttccattct ctcactacct
     8581 tattctcttt aattttgcta tgaaaaaacc atctatacca tgaatattag gatatatctt
     8641 taaatatcct ttatcttgat tgtctaagtc tacatttact gtatcaattg gaacaaattc
     8701 aaagttgtga ttttcttcaa caaaagaagt aactatattt atattctcca caccttgaat
     8761 tgtacatgta ctatatacta aagttccacc aactttgaca tatttagatg cattttctaa
     8821 aattttcttt tgtatagaag tgatgtcctt taactcttct tctttcttat acttaatttc
     8881 tggtttacgt cttattatac caaaaccaga gcaaggaaca tctgctaaaa cataatcaaa
     8941 tttacttata ctattttcat caatctcaga agcatcaaat ctttctacaa acacattttt
     9001 aagccccaat ctatttacag tagagtttat aagctttagt ttatgctcaa aaatatctct
     9061 agctactact tgaccagtat tgttcattaa agtagctaag tgagtagatt tccctccagg
     9121 agcactacat acatccaaaa taaatgaacc ttcttttgga ttaattactt tccctactat
     9181 catagaactt atatcttgaa ttgtaaataa accagcctta aataattcat ttttttctat
     9241 atttttcatt ttttcgactt taatagcttc ttctaccata ggaactttta aacatacaat
     9301 acccatttca cttaattttt caataagctc ttctctactt attttaagtg tattcgttct
     9361 tatatagata ctaggctttt cattatttgc ttccaacaaa tcttcagcaa attcttgtcc
     9421 aaatttatct atccagtttt ttataatcca agagttatag gaatacttta tagataagta
     9481 ttttacacta tcttcctcag ttatgtccat tatagtctct ttagctctta tttcatttct
     9541 aagaatagca tttatgaaac cagaagattt tttatcatat ttcttagata attttacagt
     9601 ttcattaact gctgcataat ctgatatact atctaaaaat aaaatctgat atgttcccat
     9661 tcttaaaaag attttaacat aagttgacat tttttttacc tttatttttg aaagtttatt
     9721 gattatataa tctaaataat atttattttc tattactcca taaattaact ctgttgcaag
     9781 tcctctatcc atatcactta tttctaaatt tttaaaatgc ttatttattg caatatttga
     9841 ataattgtca tttttttcta tatcacataa tactttaaat ccaacttctc ttgcatccat
     9901 ataaatttct cccttttatt aaacataaaa aagggttgtt tctaaacaac ccactttact
     9961 tttagtcatt tcttctttga gctattagta acaatctaag taattgaagt attgaaacca
    10021 atgctgctgc aacatatgtt aaagctgctg ctgaaagtac tcttctactt tgtcttgact
    10081 cactttcatc tataatacct aaattcccaa gttgaacgat tgctctactt gaagcattaa
    10141 attctacagg caatgttatt atttggaata acactgaagc cgaaaacaat agtataccaa
    10201 tttttaaaaa tggaccagcc ataataaatc ctaaaaatat taaaaaccaa gatatacttg
    10261 aagcaaaatt cactactggt actaaactac ttcttatttg aagaggtgca taacctttag
    10321 catgttgtat ggcatgacca cactcatgtg cagctactgc aacagaagtt atagatgttc
    10381 cataatatac atcttctgac aaccttacag cctttcttct tgggtcataa tggtcactta
    10441 gatgccctct aaccatttct atctttacat catacaaacc atttgaatca agtactcttc
    10501 ttgctgtttg ctctccagta tatcctcgac gtgtatttac tcttaaatac ttatttgttg
    10561 ttgaactcac tttaaattgt gcatatatag taagtaatat agctggaatt aatacaacca
    10621 ttgttgggtc aaatccccaa aaaccgccat atacagggta cataaataac actctcctaa
    10681 aatatatttt tattatacat cctcttaata ttcacttaac ttaaaaacag tttaattaca
    10741 aactaatata ttttttcctg ttaaaaagcc tatagctttt tcaatatcca tcatgtctac
    10801 attagtattt acacaaggtc cattaggtct tttgttaaat acacctaaaa caggaatttt
    10861 tttaatatct tgtattccag atgtcaaatc tctttcacat gcaacagcta caacagcttt
    10921 aggtttagtg tccattataa tttttctagc tagggttcct cctgtagcta caaatatttt
    10981 tacattagtt ttttccttta gcttaattaa ttctcctatg ttgcatcttc cacattcttt
    11041 acaattatct atatcattag taacttttaa tttacaacta ttctcttgaa tacaatgagg
    11101 tattaaaatt attatatcct ctggattaaa attatattta ttactgtata tatattcatt
    11161 atttaacttt atatatattc ttctaatatc actttttgac ataccaaatg atgatgcaat
    11221 gaaagatata ataggaaata atccactgac aatattaaaa tttattttca ttatatttga
    11281 gttaacatac tttcctttaa ttactctata agtaactgct gttgaacata gtattataag
    11341 tattagtgat attattataa tatttatcat caaggagaat atttgagtta aacttattat
    11401 aaaaaaatta acaactccta tcaaaattcc taatattaaa atcaaaatcc caacacttgt
    11461 taaatacttc tttatatctg tcatactttt cacctaaccc aatactaaac cagtttctat
    11521 agtattccct tttatatatt caccaaccaa cattctcttt ttattcggca tctgaatttc
    11581 ttcaattaaa agtacattat ctatagtact tacttttatc ccatctttgc ttacatcaat
    11641 tattgtacct acatcttttg tgcttttttc atctaacact ttagttttcc aaactttcat
    11701 tatgacatca ttataggtag tataagcact tggccatgga tttactcctc taactaaatt
    11761 gtgtatttct ctggcacttt ttgaaaaatc tatgttacct aatgatttat tcattattgg
    11821 cgcataggaa aattcttcat gattttgtac ttctcttgga gcatttcctt cttcaattaa
    11881 tcttaatgtt tcttttaaag tttctgctcc tatattcatc attttatcat gaagttctcc
    11941 tgctgttata ttttcatcaa gatttacttc tgtctttagt atcatatctc cagtatctaa
    12001 tccttcatcc atatacatag ttgtaacacc agtcttttct tcaccattta ttattaccca
    12061 atttataggt gccgcacctc tatattttgg aagtaaagaa acatgaacat ttatacatcc
    12121 aagtttagga atctctaata tttcttttgg aagtatctgt ccaaaagcta caactactat
    12181 tacatctgga tttaaagatt taattttatc tataaattct ttatctctag cctttactgg
    12241 ttgatataca ggtatattat tttcaattgc cagttctttt actgggctca tacctagttt
    12301 tttacctctt ccttttggtt tatctggttg agttacaaca cccaatattt catacttctc
    12361 atctattatt ttttgtaaac atggaactgc tatatcagga gttcccataa atactatttt
    12421 catcaaatca actcctacta cttttctatt ttgtcaacaa ataaaattcc atctaagtgg
    12481 tctatctcat gacaaaatgc tctagctaaa agctcttctc cctctaactc tattgtttca
    12541 ccatttctat ttaaagctct gacctttaca taatttggtc ttctaacatt tcccgcttct
    12601 ccaacaacac ttaaacatcc ttcctcatct atttgctccc cagatgtttc tattatttca
    12661 ggatttataa gttctataag atcttctcca atatctatta ctactactct ttttaatatt
    12721 ccaacttgag gtgcagccag tccaacacca tctgcatcat acatagtttc tgccatatca
    12781 tctaataatt gtattatctt ttcatcaatt ttttcaacct tttttgattt ttttcttaat
    12841 actggttctc ctatttgaac tatttgtctt aaagccatta taattcctcc taaatttata
    12901 atacactgtt tggattaata tctatagata cattgatatt cttatcaaat atcaaatctc
    12961 gttttgttat acatatatat tttattatac cctttaagag attaatttca atattttcat
    13021 ctttaaagag tatttgccat ctataatttt gatttatttt tgatattgaa catggatttg
    13081 gacctaatat aaatcctaaa tcatttatac cccttttttc taataaataa atcaatgatg
    13141 catgcatatt ttttatattt tttatcacta atctttcatc ttcaccacta acaactacac
    13201 ttaacatatt attaaaagga gaatatccaa atgcttttct tatttttatc tcatcttcat
    13261 aaaaaccctc ataatcatat tcaatagcat gcttaatagc atagtgttca gtgtcataag
    13321 tctgaagtac tacttttccc tctttatcag ctctccctgc tcttccagag acttgagtta
    13381 tcaattgaaa tgtagtttca aaacttttaa agtctggaaa atttaatatc atgtctgcag
    13441 acaaaatacc tactaaagtt acattctcaa aatccagccc tttacttaac atctgtgttc
    13501 caataagtac atctgcttct ttatctttaa atttatttaa tatctcatct aaagcacctt
    13561 tttttgaagt tgtatcttta tccattctca aagtttttat atctggaaaa atatatttta
    13621 attcctcttc aattttttga gttccaactc caaatggctt aacataagta cttttacatt
    13681 caggacactc ttttggaatt tctttctcat atccacaata gtggcatctt ccagtattac
    13741 ttttcttatg ataagttaaa gatatatcac aattttcaca ttgaaacaca tatccacact
    13801 ttctacaaga tacaaaattt gcataacctc ttctgtttaa aaatagtatt acttgattat
    13861 tttcttcaat cgcataacgt atttcttttt gtaatttcaa actaaatata cttctatttc
    13921 ctttatctaa ctcatctttc atgtctacca cttcaatgtt tggaagaggc ttatcatttg
    13981 ctctactttt tatatttata agtttgtatt ctccagattt tgccctataa tactcttcaa
    14041 ttgagggcgt tgctgaacct aaaataagag ttatattatt ttttaatgcc ataaatctag
    14101 caacttctat agcattaaat tttggattct tctcagactt atatgatgac tcatgacatt
    14161 catcaattat tattaagcct aaggaattaa aaggtgcaaa taaagctgac ctagctccaa
    14221 ttaacactct tactttacct gctttgacag ctttgtaaac atcatgtttt tctccttcag
    14281 atagtttact gtggaacact ccaactaaat ctccaaacct actctttagc ctatctattg
    14341 tttgaggagt taatgctatc tcaggtacta agaatatact gtctaagcct tgatttagag
    14401 caaattctat tatttccatg taaacttcag tttttccact tccagttact ccatgaatta
    14461 agtatggttt tttatcatct acaaacatat tcgactttat ctcatcaact gcttcttgtt
    14521 gctcattgtt taattttata ctttttagta cggatttgta aatacttttt ggctctctat
    14581 aataatcctt aaattctagg gttattagct ttttcttact tagagaattt atactttgtt
    14641 ttgaagcatt taataaatcc aataaatcat ttatctctac attttcatta tttttaagaa
    14701 aacttaatat ctctttttgt ttacttccca catttatttt attttgctct atataatcgt
    14761 caatcttatc actttctaaa ctcaaagata tataacatac tttcttttca tttttgtgat
    14821 ttttatattc ccaacataat tttataattc catttttatt cattgtgtac aaagaactat
    14881 ttaagtttgg tatatatttt aacttatcaa ccttaatttt acctttacta tcaatcactt
    14941 tctctactat ttctctattt ttatcactta aagttgatat tttttccttc aattcaatat
    15001 catttaatcc acttaaactt tcacctaata ggactacttt ataattattt aatttgtatc
    15061 cctttggata tatcaaattt atacattcta tataagtaca caaatatcta tttttcatcc
    15121 aataaaccaa ctctaaatct tcttttctaa atattggatt ttcatctaat atatcaataa
    15181 tttcttttat ttttattttt tcatctaagc tatctgtaaa ttgaaataca aaggcttctg
    15241 ttggtttatt accttttcca aatggtacta atattctgtg cccgattttt attacatcag
    15301 ataaaaatac aggaatttga tatgtaaata aattatctgt atatatagta ttacttctaa
    15361 ctattacctt tgcatatttt ttcattataa aacctctact taaatttaat atattgttca
    15421 tattttaata tactttacaa gatattaaaa tttcagaatt tataaacaat ttcaagttat
    15481 taatattaac tttattttaa taattaacta ttaattatat tttatacttt atgacaaaat
    15541 aaatgctgaa aactacaatt taactgacat ttgcgagttt ttactcgcta aaattaaatt
    15601 gcagctttca gccactttag ctgtgataaa atacacaaat atcatattta aaaaaggtct
    15661 tatttctcaa gcaacgcttt aactttatct aaaataacat tggctacttc ttcttttttc
    15721 atcttaggat actcagtaat atttccctct acatctatta tttttacaat attagtatca
    15781 gctctaaaac cagcaccttc tttagttaaa tcatttgcca caataaaatc taaatttttc
    15841 ttttttattt ttcctttggc atgttctata aggtcattag tttcagctgc aaatccaatt
    15901 agtatcttat cttcttttat ttttcctatt tcataagcaa tgtcataatt tctacttagt
    15961 tctattgata aatcatcatt cttcttttta atttttttgt cagaataagt ttttggttta
    16021 taatctgcaa ctgctgcact ttgaattact attttatttt cacttaaatt tgatactact
    16081 gcttcataca aatcttgtgc tgactctatt tgaacaaatt ttttaagatt ttgtggaata
    16141 gaaagatttg taggacctga tattaatgtt acatcagcac ctctagctat agcttctctt
    16201 gctatagaat atcccatttt accagaagac ctattagtta aatatcttac tgggtctata
    16261 ctctctacag ttggaccagc tgtaactatc atactttgac cttttaaatc ttgctcttta
    16321 gtaagattag tcaaaacttc ctctactatt atatctggat tagctagttt acctgttcca
    16381 atatctccac atgcaagcct tccactttcc ggttcaataa atttatatcc aaagctcttt
    16441 aaagtttgta tatttttttg aacaattgga ttttcataca tattagtatt catagctggt
    16501 gctataagaa cctgtgcttt tgttgccata acagtagttg tcaacatatc gtcagctata
    16561 ccatttgcaa tcttgcctat aacatttgca cttgctggca ctattaagaa taaatctgct
    16621 ttttttgcta atgatatatg ttcaacttcc caagtttttg gttcttcaaa catatcttct
    16681 actacataat tttgactcag cgattgaaat gtaagtggtt taacaaattc tgttgctgat
    16741 tttgtcatta taacatggat atttgcattt agttttttta acttacttac aacatcacaa
    16801 gccttatatg cagctatacc gccacttatg ccaattacaa cagttttatc ttttagcatg
    16861 accttactcc tcttctgaaa tttgttggtg ttgctcagca tgatgtctag cttcttctat
    16921 ctctatttcc tcttctgtca ataatctata tgttattttt ccacttgcaa cttctttagt
    16981 tgctacacat acaggctttt ccttagtttt atttgaaaca tatggttctt ctccatcaat
    17041 taattttctt gctctctttg aaacagtccc tactaaatag tatctgttgt ctattttttc
    17101 tagtacctca ttgatagatg gttttaacat aattataatt cctccttaaa tttctctatt
    17161 ataatatttt tatatctgct aactttattc ttttcagatg atattatacc ttctatttct
    17221 ttagcagatg tttttacatc ttcattaaat ataaaataat cataatcctt aatcatttta
    17281 atttcttcat atgcacagct aaatctcttc tctatttcag cttctgtttc tgtacctctt
    17341 ccaacaattc tattttttaa ttcttcaagt gatggtggta gtacaaatat aaatactccc
    17401 tctgggcaaa cttcttttat ttgttttgct ccttgcattt caatctccag taatacatct
    17461 tgtccttttt ctaaacattc cattattgcc gcttttggag ttccataaaa attatcataa
    17521 atttgagcat actccaaaaa ctcacctttt tctatcatct cttcaaactt ttccttactt
    17581 atgaagaaat aatttactcc atcaacttct ccagttctgg gttttcttgt agtagctgat
    17641 acagaaagtt ttattgtatc attttcttta agtagttctt tgcaaatagt accttttcct
    17701 gcacctgatg gtcctgatac aactagcaat aatccttttt tcacaaacat ttaagcattc
    17761 cccttctaat attgtattct tattctatat tttgtatttg ttctcttatt ttttccaatt
    17821 cgctttttac ttctactact aaattagtta tatttatatc agatgacttc gaacctatag
    17881 tgttagtttc tctattcatc tcttgtatta agaaatctat ttttctacct atagagtcgt
    17941 ctttaaatat agtattttta agttgcccta tatgactttt aaatctaact atttcttctg
    18001 ttatactgct tttatctgca tatattgcaa cttcttgtgc taatctattc tcatctatta
    18061 tacttgggtc atccagtaat tcacttattc tcaaattcaa tttttctcta taatcttcta
    18121 caacactact tgagtatttt tcaatctctt ctatatgatt ttttaataaa tcacatctca
    18181 tggcaatatc ttcagctaat tttttacctt cttcacttct catttctctt aatttgatta
    18241 atgcatcttc aactgcttga ttcaacattg accacaataa atcttcatct tcttcctttt
    18301 cttctatttt cacaatatca ggaaactttg caacattcat aacgctaata tcatctataa
    18361 tatcaaattt attttttatt tcttttagta tgtctatata ctgagatgct aatccctcat
    18421 caaaatttaa gtttacatct tctttgccta ataagtcaaa ctttatgtat aaatctactc
    18481 ttcctctttt tacataattt tttactaaat ttctaacttt atcctctaaa aatgaaattt
    18541 ttcttggaag acgtatgttt atatctgaat acttatgatt tatcgtttta cactctacta
    18601 aaaagtaata attatcatcc ttgtattctc ctcttccaaa accagtcata cttatagcca
    18661 ttaattaaac ctccaaaata ccttcacata tttttactgc tggacctgtc atataagaga
    18721 aatctcctac atctatttta actgttccac cttgagacgt tacatttaca ctactttcta
    18781 ccatattaag taaattgcat actattgctg atgcagtcat accagtacca caacctaaag
    18841 tatatccaca acctctttcc caagtataaa catgtatatt atacttatct tctaccttta
    18901 caaaatttac attcgttttt tcaggaaata ttttattatt ttcaatctct tttccatatt
    18961 tacaaacatc atctacatct aattcatcta ctataactac tgtatgagga acccccatca
    19021 acatagaagt aactttaagc tccctatcta aaacctttat actttcttgc acaaaacgtt
    19081 ctttatttgt aagtacagga acgtccttag ctataaaact tccttttccc atattgactc
    19141 ttatagagtt tatttctcta ttggtaagat ttatttttat atcttttata ccatctaatg
    19201 tatctactgt aaaactttct tttttaacta tacaattatc ataaacaaat ttacaaaaac
    19261 atctaaggcc atttccacac atagctgctc ttgaaccatc agaattataa tataccattt
    19321 ctacatctgc aacttttgaa tctttcacaa ctaacaatcc atccgctcct acagaaaatc
    19381 ttctatggca tacttttttt gctaaagcag tataatcaga tggatttatc tggtcgaatc
    19441 ttccatctat tgctataaaa tcatttccta ttccatgtag tttccaaaat ttcataagta
    19501 tcgctccttc gtaaattaac gcttaaacta ttataacata aaaaaattcc cataaactta
    19561 taatttatgg gaaaagtttt gtaatgacaa ctataatttg aggatgtgag ggagagttgc
    19621 cattacaatt agggtaatta tattatgttt ttaagctagt tctttctatg tttatatatt
    19681 aatatttcta tatgaatttt atgtatgttt tatttaaact gtctatgaat tttttaatta
    19741 aacatctggt aactagctat aatccttcta gtagatatct attaacatac acctattaat
    19801 tctttaagtg tttttaaaac atagtctaaa tcttccttag taatatctac atgagttaca
    19861 aatctatatt caccattttc cattttatta atttttatat ttctttcaaa aaattctttt
    19921 attaaaacat cctcttttat aatatcttca ctcatcttaa aaaataccat acttatatct
    19981 ggattaacat tgtttacttc aatgccatca attttattta attcacaagc taaatatttt
    20041 gcattttcat ggtcttcatt caatcttaaa gtcatttttt caatggcaat tataccagct
    20101 gctgcaacta tacctacttg tctcattccc ccacccataa ctttttgctt tcttctagct
    20161 tttgctataa attctttact tccagcaagt atagaaccca ttggtgcagc taaacctttt
    20221 gacacacaga acataacact atcacaacac tttgctattt ctttagcttc tacacccaaa
    20281 gttaatgctg cgttaaataa tcttgctcca tctaaatgta ctggtaagtt atgtttctca
    20341 gctatttttt taatttctct taaattatca agactcacaa ctgttccacc tgaatatgca
    20401 ttttctacac atataagccc tgtctgtggt tcatgtatgt catctcttct aattgccttt
    20461 tcaacaagtt caggatttag agctccactt tcgtcttcat ctatagttct aagctgaact
    20521 ccagctatta cagcaggtgc cccaacctca tgagtcacaa tgtgataacc tttaccaata
    20581 attatttctt gccctcttag gcaatgagta aatagagcta attgattccc aaaagttcca
    20641 cttggaagga aaatagcatc ttcttttcca actttagctg ctgctaattc ttcaagttta
    20701 tttacagtag ggtcatctct aaagattgaa tctccaacag gagcctttgc catagcttct
    20761 ctcatttcgt cagtaggcat agtaacagta tcacttctta aatcgataaa tctcattttt
    20821 tcaaccttct ttcatattta tatactatag aaccttaaaa ttgatttttt ctgtaaagtt
    20881 catatacttt catagcttat actctacaca ataattatac tatatttact ttatatttaa
    20941 tctactttaa attattaatt ttaaaaataa agtttcctct ctaataaata taaataatta
    21001 tacaatttaa atattaatct ctattgttta aattccccct agtcacaaag cgtatattat
    21061 gtgtataatt aatttactga ctcattttgg tcaaagaaag gggtgctata aatggcatta
    21121 gatggattag ttatacattc aatagtcgat gaattatcat caaaacttac aggtggaaaa
    21181 atagataaga tacatcaacc tgaagatgat gaggtaattt ttaatataag aaataataaa
    21241 gaaaatttta gattggtttt aagtgcaagt gcctcaaatc ctagagttta tcttacaagt
    21301 aattatcaaa aagaaaaccc tctaaaagcg cctatgtttt gtatgttact tagaaaatac
    21361 atacaaggtg gaaatatagt agaaatttct caaataggtt ttgaaagaat aataaaaata
    21421 agcgttgaat ctttagatga attaaaagaa aagacagtta aaaatattat gattgaaatt
    21481 atgggaagac atagcaacat aataataact catggtgaag aaaataaaat tatagattct
    21541 ataaaaagag tcccttttag cataagtaga gttcgtcaag ttttacctgg tcatgattat
    21601 tcattaccac cagaacaaaa caaactcaac cctcttgatg atatatctaa ggatttgttt
    21661 attaaaaacc tagaggaatt ggaaggacct atctttaagt ctatatattc tagatttcta
    21721 ggtataagcc ctattatagc taaagaaatt tgctacagag caggtgtaaa tcaaaatgct
    21781 atcataaagg atatatctga tgaacaattt gattctttac acaaagtatt ttgtaattta
    21841 ttcaatgata taaattctaa caaatactct ccttgcatta ttatagataa aaaggtggat
    21901 aaggtagttg atttcagttg tataaacctt acattattta gcgatttatc atatataaat
    21961 aaggatagta tgtctcgtat tctggaagat ttctatagaa ctaaggatat taaagataga
    22021 attaatcaac gttcatctga tttaaagaag agtatatctg ttaagcttga tagactttat
    22081 aataaactta aaaaacaaga agaagaatta tcagaatccg aaaatgcaga catttataag
    22141 ataaaaggag aattgattac ttcatatatt tatatggtag aaaaaggtat ggaaagtatt
    22201 gaagttgcta acttctatga tgaaaattgt aatgatgtaa caatagaatt aaataaaaac
    22261 ttgacaccat ctgaaaatgc tcaaaaatac tttaaaaagt ataacaaaat gaaacatgct
    22321 aaagtcgaga tatctcatca aatttcctta aataaggaag aaatagatta cttagaaaac
    22381 ataattttaa gtattgaaaa ctgtgaaaat ttagctgaat tacaagatat aaaagaagaa
    22441 cttgctaaag ttggatacat caagactcaa aagaaaaaca gtaaaaagga tactatccca
    22501 tctacaaaac ctcatgaatt tgtgtcttct gatggattta aaatattggt tggtaaaaac
    22561 aataagcaaa atgactatct tacactaaga cttgctgata atgatgactt atggatgcat
    22621 acaaagaata ttcctggttc tcatgtaata ataaagtgtg ctggtaagga agtccctgat
    22681 aatactgtat ttgaaggagc tatgctagca gcattcttta gtaagtcaaa actttcttct
    22741 caggtgcctg tagactatac taagagaaaa aatgtgaaaa aacctagtgg ttctaaacca
    22801 ggtatggtta tttatgaaac taacagtact atttatgtta ctcctgaaga agaaacagta
    22861 gccaagctta aggttaaatc tgaataaatt ctgcactaaa tacaaaataa atgttagaca
    22921 actacacatt atcattctaa ataaaaatag tggccttctt ataaagtaca ataatagggc
    22981 cactttctaa ttagcttact tttaattttc taacaaaata cttttctgtt ttaataacta
    23041 tacttatatt cccaacaaat attttcagtt ttcttatata gatgtaatta aaaagttaac
    23101 actaaaagct attttttaat ttagtgattt gttttagtaa ttcattatat tctgattcat
    23161 acaattcttt ttttagatta tctttttcta tagataacat agatataaca gttgtaagtc
    23221 tattttctaa tactagaaga ttttcttttt tgatttggtt ttctctacta ggagtttttt
    23281 tatttctgct aattatatat tcgtcataat tacaatcaaa ctcccttatt ttagcatctt
    23341 ttatctctat aatatagtta caaatatgtg atacaaatac tctatcatga gacactataa
    23401 gcatagtttt atcagtattt atcagtgcct tttccagtgc ttccatagat tttatatcta
    23461 agtaatttgt tggttcatca aatactaaaa aattattatc ttccaatatt attttacata
    23521 gtgctatttt taccttttct ccaccactaa gtacttttac ttttttgtag acatcatcac
    23581 ctttaaaccc aaataggctt aagtttatcc ttataaaaga ttcatcaaat gaactattaa
    23641 ctttagtatt gtatagaaca ctctttttct catctaataa actttgattt tggtcaaaat
    23701 aacctacttt taccttgtta tttattttta tattgtcatt tttatcagcc aatatttctt
    23761 ttatcagagt actttttcca cacccattat cacctaataa tgctatcttt ttacctcttt
    23821 ttatcttaaa ggaaacatta tctaacagga gcttattttc taactttaga gtcatatctt
    23881 ttatctctac tagatttttg ctaattatct ccataccatc ttgaatctta atgttcattt
    23941 ctttagaaac tttaggttta ttctttacct caagtttatc aattctgctt tttatagcct
    24001 tcacatttga gtccaacttt ttcttattag tctgaccacc cattttgtgc aacctagctt
    24061 ctgaattacc cattcttttt ggtgtttttc ttatgccctc acttaaagct tttttatata
    24121 aaagagcttt ttcaagcctt tttttctctt taacatattc ttgatactca aaatcagctc
    24181 tttttacttc ttcatctttt tgcattaaat aatcagtgta attgcctttg taagctttta
    24241 gttttccatc ttctagttct aatatagttg tacataactc atccagaaaa cgtctatcat
    24301 gagatattaa taataatgct ccctcatgcc ttttaaacat atcttccaaa accccaatgc
    24361 tttttttatc taagtttgaa gttggctcat cagctattat gatatttttc ttattactca
    24421 gcgcatctgc tatttttaac ttaacctttt cccctcctga taagtgttct tcaaatttat
    24481 ctggagcatt taaaagactc ttctccttac tatgaccaca tgtttcaata ttattttcac
    24541 tctgacttat ataagaatag ctttctgtaa ggtaagtata tccttcatca atttctattt
    24601 ctcccaatat tgcttttaat aatgttgttt ttccttgacc atttgaacca actagaccta
    24661 ttttgtcatt ttctaatatt tcaagtttat ctatatccaa aattaattta tctgcataat
    24721 atttctttaa attctctact tttactaaca acataaaaaa tccctcctta acacacttaa
    24781 atataaggag agattctata aataggcata acaaataaac gtatagacta taatctactc
    24841 tccttaattt aagcattgca aataaagcca ccaaaatagg cttttcaaaa attacaatac
    24901 tttaaattat aaaaaataga ttatattctc attgtcctag ttaccttgcc ctttctttca
    24961 tttattttta atcattatat caacattaat tacaaatgtc tatagaaaat taactaattt
    25021 tagttattca atatagaact tattctttaa atttattctt cttcaacttt aaagtcctga
    25081 ttatttaaaa ttctgtttaa tacaattcca acaattgcag ctaaactaag accagttatc
    25141 tttactgtac ttgttatagg gattccaaca gaaatacctt tattagataa atatgttgtt
    25201 ccaagaccta ttaataatat aactgctatg attaatatat ttattttact ttctacacaa
    25261 gaactgtccc ttatagtttt taatcctaca taagttatca tcgaaaatag cattatacta
    25321 attccaccca taactgaacc tggtatactt tgaagaaatc caccaaactt gcctacacat
    25381 gcaagcaata tagcaaatat tgctgtacgt ctaagtattg aagggtcata gtttttagtt
    25441 atagcaagta ctgctgtatt ttctccataa gttgtattgg ctggtcctcc taaacaccct
    25501 gcaactatag tcgcaaatcc atccccaagt aatgttctat ttaatccggg attttctata
    25561 aagtttttac ctactacagc accattagta gtcatatctc ctatatgttc cataaataca
    25621 gctaatacaa ctggagatat aatcacaatt gctcctaaac tgaacttagg aactgtaaag
    25681 ttaggtattg caaataaact tgcttctgta atagtagtta tatctactaa tcttaatatc
    25741 aaacagatta tatacccaga aaaaactgct attaatattc ctaattgttt tataaatcct
    25801 ctaccaaact tattggttaa aattgctatt gctaaagtta taaatgctat tacaaaattg
    25861 gctgaagcca tactaaaagc tgttggcaat aaatttaatc ctataactac tatcatagct
    25921 cctgtaactt gtgcaggaaa atataattta attttattta caccaactac ttttactata
    25981 atcgacatta taatataaat taatcctgct actattatac caccttgagc atatgctaaa
    26041 tctccaccat acgcctcttt agctgctagt ataactggta taaacgcaaa acttgaacct
    26101 aaaaaggcag gtacttttcc ttctgtacaa aaatgaaata tcaatgtacc aacaccagca
    26161 cagaaaattg caactgatgg attaaaacct gtcaaaatgg gaactaatac tgtcgctcca
    26221 aacatggcta atagatgttg taaagacatt atcgtttttt tcataaaaac ctccaaaatt
    26281 attatatata aataaaccct ctgtttaatt aatatctttt aattaattat cattccctag
    26341 attctatttt ttaacctcta tatacttatt atataattta tcattatttt acattttacg
    26401 acatcaaaaa ctcaaataaa ggagaataaa aactacatta agactcacat ccataaaatt
    26461 ataatattta ttttgtgcaa tctatgtaag ctttatcctc ctccctgact attcaatgct
    26521 aagcttttta tataatactt aaaaataatt actctttgat tgtaactgaa tcttctccat
    26581 caatttctaa taaactgaca gatataattt catgtctaga agtaggtaca ttttttccta
    26641 cataatctgc tcttataggc aactctctat gccctctgtc cactagcact gctaattgta
    26701 ttgatttagg tcttcctata tctataatag catctagtga agctctcaca gttcttccag
    26761 tgtataaaac atcatcaact aaaactactg tcttatcatt tacattaaaa tctaaataag
    26821 ttcctttaac tacaggttca acatgaattt tttccaaatc atctctatac aaagttatat
    26881 caatatctcc tgtatctact tttgttcctt ctatttgttc tattttctta gaaattctat
    26941 ttgcaattgg cacacctcta gtctttattc caactaaaac tagattttct acacctttat
    27001 ttctttcaat tatttcatga cttattctag taattgctct tgctattgcc ttttcatcca
    27061 ttaattgagc tttttctacc atatcataat tattgtcaaa gatataatat atctatttga
    27121 caaatctact cctttctttt aattttttat aaatttattt ttatttaaaa tttcaattta
    27181 aacaacaaaa aaacttctca tcacaagaca agaagctctt atataaaaaa tatacagtgc
    27241 aatttagcaa ttgtcttacg atatctctgt atcgtttaaa gataattttt taatctatca
    27301 aatcaaatta tatatttata tttcaaattt ttcaagcttt tttaaacaaa atactttaat
    27361 ataagatatt ttatttaaat ttcactaaat ttatttactt atataaaaac aaaaaataat
    27421 ttataagtat tatacaaatg gttattttat ctttttaata acttccttaa aatactcagg
    27481 taattctgaa ttaaattcga tatattcctt agtagtagga tgtataaatc ccaacttctt
    27541 agcgtgcaaa gtttgtcctt ttaatttaaa tttagtttct tttggaccat atacataatc
    27601 acctaaaagt gggtgattta tagacaaagc atgaactctt atttgatgag ttctaccagt
    27661 ttcaagccta gctctcatat gtgtaaactt atcaaatctt tctacaactt caaagtgagt
    27721 gattgcattt tttccatctt ttactacagc catttttaat ctatccttag gatttctccc
    27781 tataggttta tcaacagtta ttttatcttc tttaaccaca ccatagcata taaattcata
    27841 ctccctagtt atagtatgtt cctttaactg ttctgctaga aaattatgtg cataattgtt
    27901 cttagctatc ataagaagac cagaagtatc tttgtctatt ctatgaacta taccaggtct
    27961 aataacgcca tttattgatg acaacttatc tttacaatga tataaaatcc cgtttactaa
    28021 cgtattttca tagtttccag gagcaggatg gacaaccata tcctgaggtt tatttattat
    28081 taagacatca tcatcttcat atacaatatc tattggaata tcttgaggta aaacttctaa
    28141 tactttaggt tctggtatct ctataacaat attatcttcc tctttaacca gatatctagc
    28201 tttttctact ttattattaa cctttacttt tccatctttt ataatttttt gtatataact
    28261 tcttgacata tcacctaatt gttctgctag ataaatatca agtctaactt cttcttcctc
    28321 ttcaagtact aaaaactctt ttacttcatc cattatatca cctactttta ctttcaaaaa
    28381 ataaaacata tatacataaa aacacagttc ctacaactac aaatacatca gctatattga
    28441 atacatattc ccatataatt ctaaagtcga agtaatctac tacaaaacct aatcgtactc
    28501 tatcaattag atttcccaat gcaccagata taattaatat aattcccaac cttccaaata
    28561 tatgtacttt ccttgtatta agatagtata gtccaaatac tgttgcaagt aatgcaacaa
    28621 ttataaatat ccattgatta ttttgtaata atccaaatgc tgcacctcta ttttcgacat
    28681 aagttaaatg aaatacatta tttattattg gtattgttga tacatccacc aaattattca
    28741 atacccatat tttagacagt tggtctaaac ctatgagtag aattattatt aatatatata
    28801 gcaatgattt ttccccctat aaattattta aaaaccaatt ttatttgaag cacactatta
    28861 ttatacaaaa aaaatgctct aaagagcaac tttattaaaa ttgtattttc ttaataaagc
    28921 tagaacaaaa tttaaaatag tactactttt tttatattgt agatttctac atatttaaaa
    28981 tcatatcatt atgtataaaa aatttaaaaa taccatacta atcaatattt tttgtgtatt
    29041 ttatagatta aagattaatg atgtctgtaa tttaaactta caatcaccac taatcttcaa
    29101 acaaatattt ttacttttgc acttgcttat ttttatctaa atgttgtata agttcagata
    29161 ctgttacgaa tttatatcct ctctctttta atttaggaat tactacttct aaagcttgta
    29221 tagtttgtga tttatcattt cttttagtgt tataatcatg taaaagtatt atattaccat
    29281 tttggacctt tgtaaggata gtatttataa ttgcatctac tccagggtta gaccaatctc
    29341 tagggtctaa gtttgaccaa agaattatat tcatgccttt agaaactata atatcacaga
    29401 cacttttact catggctcta tatggaggtc taaatatctt tggttctact cctattacac
    29461 tttttataat attttgcgta tctgttattt ctttttcaac actactataa ctattttttg
    29521 caacatttat atgtgtaaat gtatgattcc ctatttcatg ccccccatca tattgtcttt
    29581 ttaataattc tttgttatat tctacttttt ctccaactac aaaaaaagtt gcttttacat
    29641 catttttctt taatatatca agtacttgtg gtgtaaaatc ctcatctgga ccatcatcaa
    29701 aagtcaatgc taaaattttt tcatcctcat ttcctttttt tattattaca tcttcataat
    29761 cgtcttttat attgtcattt aaactatatg cttcttttga actatcttga ttatgtgtat
    29821 tatgactata tgtatataca cctactatag ataataaaca tatacatata ccccatatta
    29881 ttttcttcat gtcattacct cttttctaat tcattctagc aatatatttt ataatgtcag
    29941 ttttttaatc tctcaatatt ccatttttat ttaaatcagt taaatttgtt aggtcttctg
    30001 aataaaagtt agaatcttct acatcagggt tttgcattgc atcacctaat aaattatttt
    30061 ctttatttgc acaatcatta cataaacttg tatctggcaa tatatccaat ctttctaaat
    30121 ctatttgatt atgacataaa tcacaaattc catatgttcc attctctatt ttagataatg
    30181 ctaagtctat ttgatacaat cttccctctt catgatttat tagactgttt tgcatatttt
    30241 gcatatataa atctgttccc atgtctccta tatgattatc ataactagat aattctcctg
    30301 atgaatactt ttcacttgta tgtttagttg tatctccaaa taaagtatta tctttcatat
    30361 cctctactaa attagttaaa ttttctcttt ctttcaataa tttatcttta tattttttag
    30421 tatccatttt taacacctct aattttaata tttacatcat aaaaatagta tgtggaaaag
    30481 taaattaaac atacaataaa aataagattt gattcgaaaa atagaatgtc tcaaaatgaa
    30541 atttttagtt catttaaccc tcttttttat ataaaatcaa atatattttt atcctttcag
    30601 caataaaaaa gagacttatc tctattttga gatagcctct tttttgaaca taatttaaat
    30661 acaatttttt gatttttata gttattattt tactaacttg ccaatttatg attattttgt
    30721 tccttaatat gctttgcttt tttaaagaat aaaagaccaa gaattattgc tacaataaca
    30781 cctattccat tagatatatt aactggtagt ctaaatcctt cttttgcttg cattatataa
    30841 ctaaatgtta ctacagtcat aaaaagtgct ggtaatgtag ttatataatg gtttttattt
    30901 gctttgacta aatatgcaga accagtccac aacattatca ttgcaagtgt ttgatttgcc
    30961 caagagaaat atctccaaat tatattaaaa tctataaatg taagagcaac accaactgcg
    31021 aataatggta aagctattaa aaatctattt ttgactgcat cttgattata attcattgca
    31081 tctgctattg tcagcctagc acttctaaat gctgtatctc cagaagttat aggacatgcc
    31141 acaactccaa gtatagctaa agctcctcca ataggaccca ttaatccaac agatactgta
    31201 tttactactg ttgctgctcc accatcatta aatatcacat taagttgagg tatgccatgg
    31261 aaatatgaca tggctgctgc tgcccaaact aaagctatta taccttctgc aaccattgac
    31321 ccataaaata ctggtcttgc ctcactctct ttctcaacac atctcgccat aagtggtgat
    31381 tgagttgcat gaaaacctga tattgctcca catgctattg ttataaataa gtatgggaat
    31441 aaaggtgttc catttggatt catattttgt aaatttatat ttggtatgtt ataccccttt
    31501 attatcaatc ctccagctac acctactgcc ataattaata atgctgctcc aaataaagga
    31561 tatattttac caatcaattt atctattggt aaaaccgtag ccataatata ataaagtatt
    31621 atcactccaa cccatatttg tgcgtttaca cctgtcaatg tctttaataa tcctgctgga
    31681 cctgttacaa atacaactcc aaccaatact aaaagaataa cactaaatat tctcattgct
    31741 atttttgcac catttcctag ataaagtcct accaactctg atgcagatgt acctttgttt
    31801 ttcattgata gatatcctga agcaaaatcg tgtactccac cagcaaagat tgttccaaac
    31861 acaatccata aaaatgctga tggtccaaat aatgctcctt gtatagctcc aaatatcgga
    31921 cctaaccctg ctatatttag aaactgaatt aaaaagattc tcttccattt cattggcaca
    31981 taatctactc catccctaca agctatagct ggagtttgat ttttgtcatt ggttccaaaa
    32041 accttttcta caaaagtacc atagacaaaa taacctacta taagtactac tattgaacct
    32101 aaaaagctta ccataaattc atccccttag tttttatata attgctttat aaatttttat
    32161 gagtttaaga aaactatttc cagttcaaat agtaatactt ttttatgcta atataaatat
    32221 taattacatt aagtgcatat ttaagtacat gaaatgactt tatatatgca ttaacagcct
    32281 aaattctttt actttgcttc tacttacagt tacttcataa tcactatttt ttaattttaa
    32341 tatgtatgta ttattaaacc atggtataat ttcttttact ttggttaagt ttacgatata
    32401 agacctatgt gttctaaaaa atgttttatc atttataaga ttttcgactt ctgatatgcc
    32461 ttcttttaat ataaactttt ctttctcagt atatataaat gtctgccttt cattagcttc
    32521 acagtaatat atatcatcaa tatctattac aactaattta tcacctttcc aaaggctaat
    32581 tttatgtgtt atttcttcta tctcctgatt tactgcttcc ttcttatatt tgtataaatt
    32641 actatttaca ttagatagtt caatatcact catctcactt ttttctaatt tattcagcat
    32701 agaaataatt ctctcttcag aatatggttt caatatataa tcaaatacat ccaaagaaaa
    32761 agcatctact gcataacttt catatgctgt tataaaaaca attttaggtc ttgatttaaa
    32821 ctgatttaat gtttttgcaa gtagcattcc atcaagatga ggtatattta tatctaaaaa
    32881 aattacatct attttatttt cctgaataaa gtctaacacc tctataccat tggtaaattc
    32941 acttactacc tcgattccac ttttattttc aataaaatat ctcaattcct ttcttgctgg
    33001 aaattcatct tccactatta tagctctcat acttctactc ctttacataa aatactatca
    33061 aagtcccatt atctattctt cttatattaa gccctcttcc atacatcagt ttaagcctta
    33121 aatgtacatt ataaagccca atcttatttt ctggcatatt atcttgatat acattattta
    33181 taatttcctc acttatacct ataccattat cctctattga tattctcaca gtattttcta
    33241 atgaatacgg taactttttt atggatattt tcactacacc agctctacca ctttctaaaa
    33301 taccatgtat tattgcattt tccactaatg gttgtataat caaacttgga atctttatat
    33361 ttacatcttc tatatcataa gatacagtta gtaattctcc aaacctagct ttttctatct
    33421 ctacaaaaga tttaacttgt tcaatctctt tatttatatc aattaagtta tcactatatt
    33481 caagattata tcttagataa gttgataaat ttattattaa ctctctagcc ttatctggac
    33541 taaatcttat aaatgaagct attgtgttta gggaattaaa caaaaaatgt ggattaattt
    33601 gtctttgaag tgcttttatt tctgctttat ttctcgcttc tatatctttt ttatctttct
    33661 caatcccctc tactatagat ataacaaatc ctattccaat ctgcccaact attaaaggta
    33721 aatatattcc accgattatt tgaattgcta aagaatgtgg atatgatatt aagtatataa
    33781 gtaatatagt aaaactttca gaaatcatgc ctaccaatat tccatacatt actctatgtt
    33841 gttttggtat cctcttatat agaaatcctg ataatacacc tgctagtata cttgataaaa
    33901 gacatggaac agatgttatc cccccaatat ccataaaata tctatgaatc cctgaaaaaa
    33961 ctcctgctgt aatacctacc atcggaccaa ataaaatgcc acctgatact atagatatta
    34021 ttctagtgtt tactattgac cccatataat ttataccact ataagttcca aatatggcta
    34081 aaaaagtaaa aactaatgct atacagacca agtcattaaa actatattct tccttttgaa
    34141 atatctgctt aaatattttt aactttgtta ttagaagaaa caatactaca ataaggcttg
    34201 tcttttctat taatgcgatt aaaattgatg ttttcataat ccccctttaa aaaataaatt
    34261 tttacacact ctaaatttat tatggttgtt ataaattaca tatttgaagt aatcctatca
    34321 caaaactttc cacatttaat cttttaatta aataagaaat agttgtactt ctattaacaa
    34381 ctaatactag ctagcataag cttgtaataa cttgtagtta ttattaactt tacaattcta
    34441 gtatttaatt ttatacttta gaaatctctt ttcttagaaa taatactttc gaatatcata
    34501 taatacaata ttatgtagat tcttactcat acaacatatt tctttaaaaa ttttatacta
    34561 ttctttgttc aaatatctca tttgatttaa ttgtgttaaa cacacattat catctctctg
    34621 ttatatattt attatatagc cgtatatcga taaagtaaat aaatcccata tttaaaataa
    34681 tatgtttgac aataaattat tataatgtat atttaccata ataatttgtc aaccttgaaa
    34741 gttacttcta taattattgt taaataattc ttctaaaaaa a
//
LOCUS       DAMJXI010000037        33929 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.039, whole genome shotgun sequence.
ACCESSION   DAMJXI010000037 DAMJXI010000000
VERSION     DAMJXI010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33929
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.039"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(109..390)
                     /locus_tag="PC465_002306"
     CDS             complement(109..390)
                     /locus_tag="PC465_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649598.1"
                     /translation="MNVYLQIGKELSEKMTKSELNKFSQEVVNFLRYAGFDKDMKIKL
                     FQTIIEAVARKKVSLPSDSEFTEGILQSDEAEMTMNVGFLIEGLSYHNN"
     gene            complement(534..866)
                     /locus_tag="PC465_002307"
     CDS             complement(534..866)
                     /locus_tag="PC465_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016040102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649599.1"
                     /translation="MPSFNRDLLVDKEKPILKNGTIAQNDSTTTDNKTLNIYNLVNKK
                     SKKVTMSATLDEELVNKLKSFSIDMNSDVSKLLSDILTQILSDVTIKEENLNIYNERN
                     RRNKTKKK"
     gene            complement(867..1676)
                     /locus_tag="PC465_002308"
     CDS             complement(867..1676)
                     /locus_tag="PC465_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDF2649600.1"
                     /translation="MANTKLLTYFNIKGGIYKTTTSIMTAYELAKDKDKKILLWDLDV
                     QANLTQYVYEINHNDNTTLDILKGISANDAIVKSPNENYINVDLIPSDIQMARFEQEL
                     SPLPAREKFLARWYMQNFNTLSEYDYIICDLSPRYDLTAKNVLFLADSIIIPIQDKNI
                     SSLRGAELFKQLWDVDRTYFDKEDNIKSTILVGFEKKKTQISDTFDSYLEGFNDMRDI
                     MLDTYIRKNEFIEKALLKKLSLTDYTKITKEHFSRQEFTNMLEELKRKGVL"
     gene            complement(2238..2960)
                     /locus_tag="PC465_002309"
     CDS             complement(2238..2960)
                     /locus_tag="PC465_002309"
                     /inference="COORDINATES: protein motif:HMM:TIGR00573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HDF2649601.1"
                     /translation="MFNSVKRFLKTLKEPVLTEFDIAKQYDFSKELSSGIVSSFKSQK
                     EIEYEKFIKFTNSKNKVLEHYIVFDVETTGLDAFKEDIIEIAAIKFERDVPSEIFSTF
                     VKPSKSIRKKITDITGITDEDVVNAPSIEEVLPHFLNFISDYTLIAHNAIFDMEFILD
                     KLYKNGYKKITNKVIDTLTLSRKYIRTYEGKKLKSYSLPSLHEELGLNYSSHRALEDC
                     KSCASVYKACKSEMKFKDELVY"
     gene            3405..5558
                     /locus_tag="PC465_002310"
     CDS             3405..5558
                     /locus_tag="PC465_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDF2649602.1"
                     /translation="MKNNINKLFLEECNAERAEHEKENYSNFNRHETYEIKKYINEKK
                     LGIKTAIANALDGGKTLFIAPTGAGKSYSFINTLKKLKTKALFILPNASNVEQAMHEY
                     NIAGAYDKIPAKQALENNNLAVMTWDKTEQLIDVDLREYIIVVDEIHQTYTDSYRGKA
                     IKNLNNIMSKCKGRIDITATPTKLEFEIYDYIIEYTQKQKTEYDVKLYNDFDNKNFTE
                     IINIINKSNNSAMLMNDISTLEFIRDSVNKNAGVVYADGKEENELYSRIVKNSDMKGY
                     ETLLNTTTILAGVNINNKDITDIIIVNIKDIGAIKQYVARFRNLKKVNVHIFNKYKEE
                     CNVYKIEWLVDKNIEKATILKDAYNKVSKHTLMFETVGINATPIRIDSNVYYCMKDNC
                     YKVDKLYIKSQIYSNYYNTRTIQSFKVLLEEYFDNVNITDAKEIETNEKELKEYKKVV
                     KEIKEATRNILKEHKEILVGYRQIKSNSKSFSLMQYHNDMKLSSKGCLEAYRAYDIHN
                     LVKKSKSNSMLELYSNYVLDNKFSLDLAWKLANTANRKRGAIFNKLNTLIYRELKEEY
                     PEFLNDELIQVTVFNYIDKLFGIGTSYTELHLQELSDDLRLILGENWNLTTKKLSIIL
                     NEVFVIEKKKYRGGNSLENIFFYKNINPKLFPLEAERMQVNNIKRYISIDDIKKDLKL
                     DEKDKSLEHAIKHTKDRMLNSLDEDEKLLLLKGFM"
     gene            5579..5917
                     /locus_tag="PC465_002311"
     CDS             5579..5917
                     /locus_tag="PC465_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649603.1"
                     /translation="MKLRIGIIDKYVAEASYELSELLIDAFNKYDEFVEAIRGGEIRI
                     VPFNLGFQALLEEDSTYDEYEFYYDDEDDKCFFHIKYRNVKDVELSKELLLELIKVNL
                     PAGAKLIVNN"
     gene            complement(6391..6744)
                     /locus_tag="PC465_002312"
     CDS             complement(6391..6744)
                     /locus_tag="PC465_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2649604.1"
                     /translation="MNIRIRKLRSSEGLKQIEFGEKLGKTKHEIYNLESGRTKVKESD
                     LKLIISLFKVNENWLRTGTGEMYNTEDRNSVKAEAFCAIDENEKLAKAVLEFSKLTDE
                     QLESILKILEVFSKE"
     gene            6941..7123
                     /locus_tag="PC465_002313"
     CDS             6941..7123
                     /locus_tag="PC465_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649605.1"
                     /translation="MNREEMICKSVKLYLSLSEKKQKDIDCIIKANNIGNIANERILD
                     IDKLNEAVEGMKKMIC"
     gene            7188..7613
                     /locus_tag="PC465_002314"
     CDS             7188..7613
                     /locus_tag="PC465_002314"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649606.1"
                     /translation="MYIENIEELKELIELFGVVEAKSESVVSFGEVESLDSCTEENAE
                     KALDILSKHKREAKNEEENEFVEFKLWTNKVEEREEIFADIACCEKCGRIFADSEELT
                     SFPVLTSYDRKRSVFEQLETVAICPNCLMNMTRIYESPF"
     gene            7724..7873
                     /locus_tag="PC465_002315"
     CDS             7724..7873
                     /locus_tag="PC465_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649607.1"
                     /translation="MKKISEMSILEKADFIRNRQIELKKKYQNKAKGELFNIACREIE
                     EKEKM"
     gene            7887..8240
                     /locus_tag="PC465_002316"
     CDS             7887..8240
                     /locus_tag="PC465_002316"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649608.1"
                     /translation="MIGYKLVKNSEFLKLKEELESKKDELKLKDEELKKRLGELSELH
                     LSKASLYMNLGMTIMEKEFYNSIIEKLFDKDFKKAISIFNKTKKLRIKNKKATEILLR
                     VNKEEKIKEFPCRYK"
     gene            8252..8527
                     /locus_tag="PC465_002317"
     CDS             8252..8527
                     /locus_tag="PC465_002317"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649609.1"
                     /translation="MNRFRLDEAISITRRDIKELSGYSNDIKECKKVKVTIIKKNGIK
                     VPITFSNELLYDFLKKGFEISFKSMCEEAAETEKELLRMKEGSVRNE"
     gene            8520..8777
                     /locus_tag="PC465_002318"
     CDS             8520..8777
                     /locus_tag="PC465_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649610.1"
                     /translation="MNKMNVTQALEKFDSLLDKYNDLPDYVYTLEYRCKFYEWIRALE
                     RKKELKNYKIVNVLTAERNRETAPFWDLEKDVAKWIRKGKF"
     gene            8753..8905
                     /locus_tag="PC465_002319"
     CDS             8753..8905
                     /locus_tag="PC465_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649611.1"
                     /translation="MDKKGKVLKICGWCGKAFFSDDNGKVAYCSNKCKSKREKSLKKE
                     RFKDEF"
     gene            8895..9155
                     /locus_tag="PC465_002320"
     CDS             8895..9155
                     /locus_tag="PC465_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649612.1"
                     /translation="MNFKMIANIPGSWTVQKQFEKVLEEILELKEAIALEDNKKILEE
                     GLDVFQAILTLFKIIGIHNIREGLKEHNKKLRRRKWKLEKID"
     gene            9403..9864
                     /locus_tag="PC465_002321"
     CDS             9403..9864
                     /locus_tag="PC465_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649613.1"
                     /translation="MKIKKEYIDKVENILKMLGDEYRKLRVLKKEIAILKHKENYREI
                     NYEELGFKVQKSVKSIDDMVITIEDVIYNKETEIEIIERKLEFYNIYLKELSELEQKM
                     IELIYFYNWDEKLPITKIAYELNYDRSSLYNKKAIAINKIALMIYGDEALE"
     gene            9966..10433
                     /locus_tag="PC465_002322"
     CDS             9966..10433
                     /locus_tag="PC465_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649614.1"
                     /translation="MVELKKEYIDEVIKLLDEVRELRVRKEVLNDEIEFLKKNEKLSS
                     INFNELGFPVRSGSYSIDDMIINSQEKIYIKETEIEIIDSRIEMINIYTKRLSEEEQE
                     IISLRHFDSKINSYGEISELLMISKTVVQRKYTDALRKIVLMKYGEKAKKDRE"
     gene            10603..11181
                     /locus_tag="PC465_002323"
     CDS             10603..11181
                     /locus_tag="PC465_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010074671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2649615.1"
                     /translation="MRRTQEVLDIQEYLRYKSYRNYVIFMLGITTGYRAGDLVKLKVR
                     DVREALKRQEFTIMEGKKANSKNIREKNRKPRTVEIRPRIAQILKKYIKDKHDYEYMF
                     PSRKRKYPHIGVEAVSKALKEAGEYFGLYDITAHSMRKTYAYKIYIDSEKDIVAVKEL
                     LGHSSIEETKMYLGLDKELYHHYSESLDDFVR"
     gene            11378..11593
                     /locus_tag="PC465_002324"
     CDS             11378..11593
                     /locus_tag="PC465_002324"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649616.1"
                     /translation="MKKIELDDKEIKLIISALDLKVSRNLGKAYKNFPYAFDEKEEYK
                     RDVATMELLIDKFLSKLNEVECEGVLI"
     gene            11593..11886
                     /locus_tag="PC465_002325"
     CDS             11593..11886
                     /locus_tag="PC465_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDF2649617.1"
                     /translation="MAREFSRSFYNSKAWKECRQSIIKKYLGLCAECGKLGEEVHHIK
                     YLTPANIHDVEITLGEENLILLCKDCHSKKHKSKKDITRTGLKFNEKGELISI"
     gene            11984..12373
                     /locus_tag="PC465_002326"
     CDS             11984..12373
                     /locus_tag="PC465_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649618.1"
                     /translation="MGGGLFKIIYEQLEKEKKIKQEVSRLKKNYKDLEKEKVKILDGL
                     VNEAAFLKISLEETREILTKEGLTEIFKQGKQEFERERLQVKIYLNFMKLYSNVMKQL
                     IDIIPSDMKQEEEDELIKFIKKGRLNK"
     gene            12370..14019
                     /locus_tag="PC465_002327"
     CDS             12370..14019
                     /locus_tag="PC465_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HDF2649619.1"
                     /translation="MTYIEEYYQKILNGEIVACSRIKQVYKKLVQDLYNPKENWVFDE
                     ELANRPIEFIETFCKQAQGKLGEPLKLELFQKAKHQAVFGFVDKETGFRKYQEVLDIR
                     GRKNGKTTELAADELFMLIADNEGSPEVYNIATKYEQAQKGFKECYKMVQQSKILSKH
                     IKKRKSDLYFHANYGFLQALASNSNGLDGLNSHMVTIDELAAIKNRDIYDLMKQSMSA
                     RNQPLLNCITTNGFVREGIFDAQYEYACNVLDGKIKDDRFIAFIYELDDKDEWDREEC
                     WIKANPGLGTIKKLDFLRDCVNKAKTDPSFKPTVMVKDFNMKENSATAWLRWDELNNE
                     TKFNVNEMEFRYGIGCFDLAETTDLASAKVLLKKRYDDNIYTLSMYWVPSERLKQKVD
                     EDKIPYDLWEKQGLLRVCEGNKINPYDLLLWFREIKEEHDIYIPWIGYDPWHVDSSLL
                     LAYENEFGKDAMIKVRQGVYTLSAPMKELRADLKANKVIYNNNPIDKWCLSNIEIKTD
                     INGNIQPIKGMDRRRRIDGGVTLIIGYVVLKEKMSEYENMI"
     gene            14035..15189
                     /locus_tag="PC465_002328"
     CDS             14035..15189
                     /locus_tag="PC465_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF2649620.1"
                     /translation="MNIFKSKKKNKEAPERIVMELILDLGNGFYSWHGNLYRSDIVRS
                     IIRPKAKAVGKMAAKHIRSNETEFKTNPEPYIKFLLENPNPFMSGQILQEKMVTQLEL
                     NSNAFAVIIKDDDNIPTQIYPLNALNFEAIYEDRVLFLKFLLRNGKVVTYPYSNIIHL
                     RKDFNENDLFGTPPTKVLKALMEVVNTTDQGVVKAIKNSNTIKWLLKFKTSLRPDDIK
                     KEVKEFEKNYLQIDSEAGGAAATDSKYDAEQVKAESYVPNAAQMDKTTQRLYSFFNTN
                     EKIIQSKYTEDEWNAYYESEIEPVGLQLSKEYTQKLFTRKERSFGNEIIFEASNLQYA
                     SMSTKLNLVQMVDRGSLAPNEWRKIMNLSPIEGGDKPVRRLDTAIVEGGD"
     gene            15195..15932
                     /locus_tag="PC465_002329"
     CDS             15195..15932
                     /locus_tag="PC465_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HDF2649621.1"
                     /translation="MASDNLKEFLKVKSSTETNADLFFYGDIVCDEWDAWTEEDQYPL
                     AIKDFLAQEQGKDLNIYINSGGGSVFAGMAIYNMLKRHEGFKTVYVDGIAASIASVIA
                     LAGDRVVIPQNAYFMIHKPWIGLCGAYNSDKLIKAAEDLDRIEEGILNVYQDNLKEEI
                     DIEEIKEKLSEETWFTGKEASNYFNFEVDEKKEVAACVSDYFDKYNKVPHALKNKIDK
                     TSNKKENNNKKRVQMKLDLLKLGGLND"
     gene            15925..17193
                     /locus_tag="PC465_002330"
     CDS             15925..17193
                     /locus_tag="PC465_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HDF2649622.1"
                     /translation="MTREEYFKKRQEMIDEAQKLLDDEIGEEGTGEEKTEEAEKIANK
                     IKALDEEYERNVKARANLKALQDDVKIDPTIFNLTNNKGKIEGIEDTTVKDEQEQYKN
                     AWAKDMLGKQLNSEEQEIFNSINSAYRAEVQTSENNTILIPKTVASGIWKEIGDMYPL
                     FGDASPTFVAGDLTIIAEEDGGDDAAWYDEETEVKEDGYKLKEITLRGCELAKDITVS
                     WKLKKMSIDEFVPYITTLLAEKMGAALAKAIVDGKGKPGESDSFKPQPLGIKTALSKE
                     VSKAQIIEYTDKIAYTDITKLMSVLKKWSNGACIYANSTTIWTQLAEILDTTGKPIFI
                     PDAANSDGVGRMFGRVVKMDDSMADGEILAGNISKGYAININENVTLYTDEHVKSRKT
                     DYLTYSLVDGNVISNKAFGMIVKKTSAVAK"
     gene            17203..17490
                     /locus_tag="PC465_002331"
     CDS             17203..17490
                     /locus_tag="PC465_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HDF2649623.1"
                     /translation="MIVSLEEIKEYLRLEADYKEDDNLLLSLLKAAEEDLENRTGKVF
                     NETNKSELVSLYVKMYVAEQYEKRGATESNSEKVRFVLESIISQISICSRY"
     gene            17494..17832
                     /locus_tag="PC465_002332"
     CDS             17494..17832
                     /locus_tag="PC465_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HDF2649624.1"
                     /translation="MDIGKLTQRIDIQIYGEIENDIGEVTKGWATYKKLWANKSLLRN
                     SNNYVLDKENIEYSYRFKIRYRTDITEAMRIVCNDVVYDIKHVNNIKELNKYETNIDC
                     ILYKEGVYNE"
     gene            17825..18238
                     /locus_tag="PC465_002333"
     CDS             17825..18238
                     /locus_tag="PC465_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HDF2649625.1"
                     /translation="MSNTDFNMNGLDDYTNKLFKRIVKEYPKKAEKLMNISLGKCKGE
                     AIARTPKSDKKPKKYKRAKHMKDNWKTKTQSKNGNFVGVLKNNSPHAHLIENGWVTKN
                     GGYVEGKHMLQQTMEHQRAKIDKRIEKMVDETFNL"
     gene            18250..18666
                     /locus_tag="PC465_002334"
     CDS             18250..18666
                     /locus_tag="PC465_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649626.1"
                     /translation="MLKIVSVKKAIVEKLKSLNIKIVANEIRSGFEKPAFFIQIIPIE
                     MASDPSFSNSTLLVNIHYFSKEKTELENLKMIDKLNILFQDCILEIEGGKLTIEEKSV
                     EIYENVLQYKFNLQVVEIIEEDESKYELMKELEMNI"
     gene            18683..19750
                     /locus_tag="PC465_002335"
     CDS             18683..19750
                     /locus_tag="PC465_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HDF2649627.1"
                     /translation="MGLPSAIIEFQRRSRTVKFRSRRGIVALILKDSTAIKKSYSIDF
                     LTDINETEFTKENYDYIRLAFLGKPSKVIIEVINDSVDSERSLDDALKALRENKFNYL
                     AIPFISEEVDKTKIVNWIKTARREKEIYKAVLPSVTNANEKAIINFSTTGIKVGEKVY
                     TTAEYTARVAGILAGISLSESCTYFVLDEVTEIEPTENPDEAVDEGKLILINNNGIRI
                     ARGVNSLITLSKEDTEDLKKIKIVEAIDMIQDDILQTWNENYVGKVTNKYDNKILFLS
                     AVNNYFKELQRDEVLDNSQEAYAQIDIEAHKKYLKEKGIDYSEMTEQQIKEANTGSYV
                     FIEGNITVTDAMEDLKFKIYM"
     gene            19764..20213
                     /locus_tag="PC465_002336"
     CDS             19764..20213
                     /locus_tag="PC465_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HDF2649628.1"
                     /translation="MGKENIVGSSQISGTWGKLWWDGTLIAEVLSFEAKVTANREEIQ
                     FGMSKDSKITSLSGEGTVKLGKVYSRGKKKLLEAWKNGEDPRSTLTSKVKDPSTPGKQ
                     AETVTINNVWFNELALSQFEKGGKIEEELSFGFTPNDSDVMDEIDEI"
     gene            20260..20643
                     /locus_tag="PC465_002337"
     CDS             20260..20643
                     /locus_tag="PC465_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF2649629.1"
                     /translation="MDNKKEMVTIEDILRRKEYFAKKSEETKQLYIPSLDGNIEISKP
                     DRMLCLDAIEMEDAVEGDKYFVYEIVKSPNLKSEKLHAEFGCKDNPLDIVDVLFEAGE
                     ITDIVKIATKFAGFGVVEEIEDLKN"
     gene            20667..20834
                     /locus_tag="PC465_002338"
     CDS             20667..20834
                     /locus_tag="PC465_002338"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649630.1"
                     /translation="MISHYLEKGVDLDKLTNLNMIEKNFHIACMLYEEEEKIKLISEL
                     IGAMFGGVKNG"
     gene            20827..22581
                     /locus_tag="PC465_002339"
     CDS             20827..22581
                     /locus_tag="PC465_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649631.1"
                     /translation="MARRHIGAVISLKDNMSATMRGIRREQKQFQNEVRRTRNEMRSA
                     SRERMRIRMDATPAHRTIQDLRRKFAPLRTKLVKAVVIKDLATEKIERIKSNVKSFGK
                     FIARPVVKLKDETKGMIDKIKNRLTSLSTIVPVGAAVGAAGMAVKSGMELEQQQISMR
                     HFMGVGNKGKSSKELDGMSASYLKDLRNNANATPFETGEVISAGTRSLQIAGGNTKDA
                     MQMVKLAEDMAALNPGKTVGDAMEALADMNIGEMARLTEFGVKASSTDDPKEVQKKLE
                     TMYAGGANKLAESGSGLLSTIMGKLKSNIADIGLGMLEPLKPVMTGLIGFIDQASPKI
                     LEVGTKITSGIGMAIGWIQQQMPTLAPIFQTAFGAVSSIVSTVAPIIGQVIGALSPVF
                     IGLLSVASSALSGIASAVKTVAPVVSSLISKLAPIFLNVGSTLKSMGKIFKNVFDSVM
                     KIVKKASDFIKPLVNGIIGATKGISDGVSWVAGKLAGNATGTKYWSGGLSVVGEHGPE
                     LVSMPRGSKVFTNAESKSMINKSIPNFRQVQGENTNYNITIPKIAEQIVIREDADIER
                     ITSSLIKKIQMAKMGGVV"
     gene            22581..23219
                     /locus_tag="PC465_002340"
     CDS             22581..23219
                     /locus_tag="PC465_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDF2649632.1"
                     /translation="MEMWLRQSNDSFRFPILPTSFEISGNINTSTTNVLKLGEVIVCG
                     GMGLRTTEINSFFPGEQYHFCNYKDFPQPYDCVNKLKKWMEQGLILRYIITETDVNME
                     VIIESFKHGKQDGTNDVYFTLSLKEYKRIQIPKVNTNNDEKLSSVKDVPLTKGFEVKK
                     QRTHKVSKGDSLWSLAKKYYGNGDLWKKIYDANKKLIKNPDIIQDGWVLVIP"
     gene            23459..24979
                     /locus_tag="PC465_002341"
     CDS             23459..24979
                     /locus_tag="PC465_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2649633.1"
                     /translation="MIINRSKDSSNNSISFVSKDMGFLLTQSEVSYNFKDKLVEDIAK
                     QVFNDNKLAIGNIPKTNVKYTKMFIGVTGYDTIMSAYTEASKTTKKKYMIESNLDKFN
                     VIEKGIITLNVMFEEGSNLINTSFSESMENVKNKVLVVDQYGNKISEKIDDKIFKDVG
                     VIMQKVIQQQENSTVDIESEFKGIEQTCSLKGYGDVTCITGRGVKVKDSYTGLTGLFY
                     IDTDKHNWDSNGNYEIDLDLNFQNIMDEKTAGQDEQKEESSDLNGEGTLNGREVKAEF
                     TAYYPSNNPMEGGYYQAMDGKRLVPSNNTCAAPSKLKFKTKIQAKCPGTKIDGKTYTV
                     TDRGGAIGLKNGVYRIDILMSSEKECNDFGRRKGTIIIGDGTGYTNATGKAKELISIA
                     KSKLGCKYVWGATGPNTFDCSGFTQWCYKKIGINIPRVSRGQGKAGKAVSKGSLQPGD
                     LVFFSSKGANGTIDHVGMFIGNGEFIHSPHTGDVVKISKLSGSYYTKNYVTARRYL"
     gene            24995..25321
                     /locus_tag="PC465_002342"
     CDS             24995..25321
                     /locus_tag="PC465_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HDF2649634.1"
                     /translation="MSDPINEFIGIIREEGKHYNEPSFFVGKIKSKLPDLKIEINNIV
                     LEKEDILIDSWMLDRQIESFDTETNQEHQHEVKNPFIDTFESGDIVIMFKIGDKFAVV
                     SKLVSL"
     gene            25321..25749
                     /locus_tag="PC465_002343"
     CDS             25321..25749
                     /locus_tag="PC465_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HDF2649635.1"
                     /translation="MSTIFPFIGVPEDYILPKTEELPIFREVAWDFEKDEPILENGDF
                     KIIEGNEAIKIWVYKCIKTNRYEHEIYSWGYGTELSELIGQKYSKGLTESEASRYIKE
                     ALLVNQYILDVNIKDTKFTDDLLSVNIEISTIYGEVEVNV"
     gene            25742..26794
                     /locus_tag="PC465_002344"
     CDS             25742..26794
                     /locus_tag="PC465_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HDF2649636.1"
                     /translation="MYSSQTYDVIKNRTLSNIDLDIYKGEGSFLSDMVSPISTELAKF
                     YIELSYLHKKAFIEDNFDDFLDKRVNEFGVYRKLGTEATGEVVFEGKAGTVIPNGTII
                     SYNELLFVVIKDIVISSEIEQNTSPVQALEIGIRYNIPASTEFKLQDEINGISKIYNN
                     LDFKGGTEIETDEELKERFYKIQRNQATSGNKAHYEEWALEVEGVYNAKIYPRWDGPG
                     TVKVLIFGENNQAVDTEVIERCKEHIEEEMPIGPALTVLTPSVLDISISASIKLEAGY
                     TLDFVKESFLESINSYLINVNKEIIYTKVSAILASIEGIHDFSNLLLNNKAENIVFEE
                     DKVPSVTTLEFSEVVV"
     gene            26794..27402
                     /locus_tag="PC465_002345"
     CDS             26794..27402
                     /locus_tag="PC465_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HDF2649637.1"
                     /translation="MKLIDKLPSFYNNNVTSKIQEAYDIELETLRETYDDTFDQFFVD
                     TATWGLDYWENILSIKNRFDLNIEDRRSNIKAKMRGKGTTTIEVIKAISEAYTKTNVD
                     VEVFSNLFSFTLSFITNDCSYNTILELDKKIEEIKPAHLEHKFERVLFDKSRLYAGAT
                     ISAGETVTIYPYVPRDLESFGEIAICSGNDRALEKVTLYPKK"
     gene            27419..28198
                     /locus_tag="PC465_002346"
     CDS             27419..28198
                     /locus_tag="PC465_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDF2649638.1"
                     /translation="MAEQQYFTLVTDIGKAAIANASVTGEKVDFAKIKVGDGGGSSYT
                     PNESQTALKNVVWESTLEHAQVDKDNPNWVVIQKFIPGDVGGFEIREVGLFDSKDQLL
                     AVSSYPTTYKPEADSGTVKELLIKVILVVSNVANINLKVDPTVILATLKDLQDLDSKI
                     DTTKTELTNSIETAKTELNNKIGDTTQLETTDKTSLVGALNEVKTSVDSIETTAEKTS
                     YNNATSNLTATNVQGAIDEVVRKIENFNEVNISIQNDMLPI"
     gene            28216..29904
                     /locus_tag="PC465_002347"
     CDS             28216..29904
                     /locus_tag="PC465_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649639.1"
                     /translation="MQTEWNFDFKAEAQPITLKAGKYKLECWGAHGKVWGGDSQSSGG
                     YSYGELTLKKETTLYVYTGATGSSNKYEEFTFNGGGLGVNSGGGGATDIRLVNGDWNN
                     KQGLLSRIIVAGGGGGAFSKTPAGKGGGFKGGNSTNDDNSSMLIVPGGTQYDGGRGYC
                     DEWDGVFGCGGGSILGLEQGKYPYNSGGGGWFGGAGARNISSGGGGSGYVLTKDSYKP
                     VGYIPTSEYWLENVGSITGGNTAKVNGYAKITLLQALPFLTVSSYNSTQATFKAAHTD
                     PTLLTKIEYFIDDILKETITTDLTLEKTINYTLEDNALHTLKIVVTDSANATAEKILS
                     ISKGIAPLPSASSLEDVTNKWMEIKDAFKTGKTSIINTLALKNIEASLNNTLVELSEK
                     IKTSFDSSDASVQDLMNQLTQANNTISQLNTRYKVASGTVTPFKGDDTKIAYPYLTDR
                     VFKPSAWVKISNLDFKPNIFFADFDYYDTEYKNNYKLFLFACCGVATQRGVDFSSVTS
                     FVRKSSDEYFHANGWLYNNSEGDVYFNNTGVQIPAYSFDSTQRHIYKWYAIKFI"
     gene            29919..30215
                     /locus_tag="PC465_002348"
     CDS             29919..30215
                     /locus_tag="PC465_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649640.1"
                     /translation="MNVPNRVIYDQTGKIIFETGESCGDVLPHNKITELHYIDIPYGS
                     IDYIKNRIVGINIETKQPILEEIPVYVSEAEKEKQELENQLLLLTNQEIGGGIL"
     gene            30215..30397
                     /locus_tag="PC465_002349"
     CDS             30215..30397
                     /locus_tag="PC465_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649641.1"
                     /translation="MNINNVVVRILAERILNKGLNPLKNRPFELDDVTNTEYRKAVED
                     YIIKESGVVEGAEPTA"
     gene            30434..30664
                     /locus_tag="PC465_002350"
     CDS             30434..30664
                     /locus_tag="PC465_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HDF2649642.1"
                     /translation="MNEEVIKEKIKRNEIRINRHSDEIDELKIANIESKAELKALCEN
                     LNSLTSMLKWLIGTMITTLIGFFIFAIQRGIF"
     gene            30681..30938
                     /locus_tag="PC465_002351"
     CDS             30681..30938
                     /locus_tag="PC465_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDF2649643.1"
                     /translation="MDNLISFIPEQLLILVAALYVIGAGCKKYKQLDNKYIPVVLLIL
                     GIGFSIWMLGLNPSAVLQGIICWGVAIGINQTYKQLKEENK"
     gene            30938..31750
                     /locus_tag="PC465_002352"
     CDS             30938..31750
                     /locus_tag="PC465_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2649644.1"
                     /translation="MKICITVGHSILKSGACTSADGVVNEYQYNKFLAPVLADTFRKE
                     GHKADVIICPEKQFKTKAEEKIYKIPRVNSGGYDLLIELHLNASNGQGKGSEVLYYSN
                     KGLEYATRICNKLGTVFRNRRAKLDKGLYILNSSKPTAVLIESFFCDNKEDYEKAKKL
                     GYEGMAKLIVEGVLNKNIGDEGVKEMYKHTIVYSGEVDKIPATVVGWGYNDGKILICD
                     IKDYVPGQTENLYIVGGGACEKISSITKEHYTMIKGNDRFDTLYKALDFIKK"
     gene            complement(31777..31986)
                     /locus_tag="PC465_002353"
     CDS             complement(31777..31986)
                     /locus_tag="PC465_002353"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649645.1"
                     /translation="MKDVFEELISIKDACELYKKGESTLRLNIRNGKFVEGVDCKKFG
                     TTWVFKKTALEREYNKKDKKRESGN"
     gene            32136..32585
                     /locus_tag="PC465_002354"
     CDS             32136..32585
                     /locus_tag="PC465_002354"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649646.1"
                     /translation="MEKFIRLDYDKGFRGKEHVSSATGDGEHFEAGISCYKISKEKCV
                     DAIINLCEYWFEFAGECQFKDFDINIFEGCYVGEGASYEDLATCEKHLYTVDGSLFNE
                     VYDLYYMHETYLEENGNVEELEENYKDEYITTEEFETKIKEMFIKYL"
     gene            32597..33232
                     /locus_tag="PC465_002355"
     CDS             32597..33232
                     /locus_tag="PC465_002355"
                     /inference="COORDINATES: protein motif:HMM:NF013043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HDF2649647.1"
                     /translation="MKIGDKFENLTILDIEQKNGRKYCLCKCSNCNNEKWIRADSLKR
                     IKACGCMKSNTQFKQNDLTGKKFGRLTAIKNTNKKAKSGHYIWACKCDCGNEIKTAEN
                     NLTTGRTKSCGCLKKESNIKNAKIALKVHKEKNIIDDTNLSIIKKTEAYSNSKTKIRG
                     VSWNKEKRKYCAQIEFKKMHYNLGYYDNIREAEEAYKKAKEKFLKEINGKV"
     gene            33309..33780
                     /locus_tag="PC465_002356"
                     /pseudo
     CDS             33309..33780
                     /locus_tag="PC465_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894340.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT        13467 a         3813 c         6361 g        10288 t
ORIGIN      
        1 aatttaatct atatctatat gatataatat cacattattt ttagattaac tatacggaaa
       61 taaaagcagt gtattcaata aatgcactgc ttttttaatg ctaaagattt aattattatg
      121 ataactcaat ccttcgatta aaaatcctac gttcattgtc atttctgctt cgtcgctttg
      181 caatattcct tccgtaaatt cgctgtcgct tggtaatgat actttttttc ttgcaactgc
      241 ttctatgatt gtttgaaata gtttaatttt catatcctta tcaaatccag cgtatcgcaa
      301 aaaatttaca acttcctgtg aaaacttatt taattcagat ttagtcattt tttcagataa
      361 ctcttttcca atttgcaaat aaacattcat cttttccaac ccctttttag attatagtta
      421 aaacatatta tttaaacaat attgatatat tgtaataata atattaaaat attacttaaa
      481 tattatatat acaatattta agtaatatct aaacaatata aatataatat tatttacttt
      541 ttcttagtct tatttcttct atttctctca ttgtatatat ttaaattctc ttcttttata
      601 gtgacatcag ataaaatttg agttagtata tcacttaata atttactaac gtcgctgttc
      661 atatcaatag aaaaagattt taatttgttt acaagttctt catcaagcgt tgcactcata
      721 gtcacttttt tacttttctt attaactaaa ttatatatgt ttaatgtctt attgtctgta
      781 gttgtagaat cattttgtgc gattgttcca tttttcaaaa tcggtttttc cttatcaact
      841 aaaaggtctc tgttgaaact tggcatctat aacactcctt ttcttttcaa ttcttctaac
      901 atattagtaa attcctgtct gctgaaatgt tctttagtta tttttgtata atctgttaga
      961 gatagttttt ttaatagtgc cttctctata aactcatttt ttctaatgta tgtatctaac
     1021 ataatatctc tcatatcgtt aaacccttcc agataagaat cgaaagtatc gctaatttga
     1081 gttttcttct tctcaaatcc aactaaaata gtacttttta tattatcctc cttatcaaaa
     1141 taggttctat caacatccca gagttgttta aataattctg ctcctcttaa agaagaaatg
     1201 tttttatctt gaattggaat aattatacta tctgctaaga aaagcacatt tttagctgtc
     1261 aaatcgtagc gtggagataa atcacagata atataatcat actcactcaa agtattaaag
     1321 ttttgcatgt accagcgagc taaaaatttt tctctggctg gtaaaggtga tagctcttgt
     1381 tcaaatctag ccatttgtat gtcagaagga attaagtcta cattaatgta attttcatta
     1441 ggtgacttga ctattgcatc attagcacta atccctttta aaatatctaa tgtagtatta
     1501 tcattatgat ttatttcata aacatattgt gttagatttg cttgtacatc taagtcccat
     1561 aagagtattt ttttatcttt atctttcgca agttcatacg ctgtcattat agacgttgtt
     1621 gtcttataga tacctccttt tatgttaaag tacgtaagta gctttgtatt agccattttc
     1681 tccacctcat tattatattt ataatattat aataatattg tagtattgtt tttataatat
     1741 tgcaacaata tattaatatt gttaattaca atattcaaat aatataaata caattaaagt
     1801 aaaaaattat ctagactttt tgaatttgat ttttaaatca aattcccaac cactcttagt
     1861 cgcgtttgag tggttttgtg tttttaaact aattaacata tatgaagtga tgtaaaattg
     1921 tatctttttt taaaaaatgt gatataataa aagcaaggaa ataatgattt accttacaca
     1981 agagtagcta tttccaatgc tttgaaaaat aacttatttt cttaaaccac tcttagtcgc
     2041 gtttgagtgg ttttttattt tatcatatat gaaagctgat ataacaccag ctagtatact
     2101 caataaaaaa tttatcacca tactgttcca cctccttccg ttatggaatt tggcgtttaa
     2161 atatggaaat agccaccctt acgcttttca atcatttttt ccttgctaaa attattataa
     2221 catattttaa caactaacta ataaactaat tcatctttaa acttcatttc gcttttacaa
     2281 gctttataaa ctgatgcgca actcttgcaa tcttctaatg ctctatgaga actataattc
     2341 aatcctaatt cttcgtgcaa agaaggcaaa gaataacttt ttagtttttt accctcataa
     2401 gttcttatgt actttcttga caaagttaat gtatctataa ccttattagt aattttttta
     2461 tatccattct tatataattt atctaatata aattccatgt caaaaatagc gttatgagct
     2521 ataagagtat aatcacttat aaaattcaaa aagtgcggaa gcacttcctc aatgcttgga
     2581 gcattaacaa cgtcttcgtc tgttattcct gttatatcag ttatcttttt tcttatactc
     2641 ttacttggct tcacaaatgt actaaaaatt tcgcttggga catccctttc aaatttaata
     2701 gctgctatct cgataatatc ttctttgaaa gcatctaaac cagttgtctc tacatcaaag
     2761 acaatataat gctctaaaac tttattttta gaatttgtaa atttaataaa tttttcgtac
     2821 tcaatttctt tttgactttt aaaagaacta actatgccac tagaaagttc tttgctaaaa
     2881 tcatattgct ttgcaatatc aaattcagtt agaactggct cttttaatgt ttttaaaaat
     2941 ctttttactg aattaaacac aaagtcatcc cccctttaca gtttaattat aaaaaataag
     3001 acttagtttg tatactaagt cttagtaaaa tttaacattt taaaaaaata tttctaaaat
     3061 ttaattgatt ttttaaaaca gtatattttt ttataatcta aatgtgctat aattataatc
     3121 ataaaatgag aataagccga tttttttaaa ttagattttt aaaatacaaa aaaataaaag
     3181 aggaatactc acttgccgtc aaacaatagt attcctcacc atcagggaaa atggaccctt
     3241 attttgggat acacaaatat ccttattttc taattgctat attcttatta tagagtaaaa
     3301 agcaatagaa atcaagtttt tttagagtat ttttaattag taaaattcta ctaaaaaaca
     3361 gaaaataggt tttatttttc cctgtaaaat aagggggatt taaaatgaaa aataatataa
     3421 ataaattatt tctagaagaa tgcaacgctg aaagggcaga acatgaaaaa gaaaattatt
     3481 caaatttcaa tagacatgaa acatatgaaa taaaaaaata tataaacgaa aaaaaattag
     3541 gaattaaaac ggctatagct aacgctttgg atggaggtaa aaccctattc attgcgccga
     3601 cgggagcagg aaaaagttat agttttataa atacattaaa aaaattaaaa actaaagcat
     3661 tattcatact tccaaatgct tctaatgtag agcaagcaat gcacgaatac aacatagctg
     3721 gtgcatatga taagatacct gctaaacaag ctttagagaa caataatcta gcagtaatga
     3781 cctgggacaa gactgaacag ctcatagatg tagacttaag agaatacata atcgtagttg
     3841 atgaaataca tcaaacttat acagacagct atagagggaa agcaataaaa aatttaaaca
     3901 atatcatgtc taagtgtaaa ggaagaatag atataacagc aacaccaaca aaactagaat
     3961 ttgaaatata tgactacata atagagtaca ctcaaaaaca aaaaacagaa tatgatgtca
     4021 agttatataa tgattttgat aataaaaatt ttacagaaat aattaatata ataaataagt
     4081 caaacaatag tgccatgcta atgaatgata tatcaactct tgagttcata agagattcag
     4141 taaacaaaaa tgcgggagtt gtatatgcag atgggaaaga agaaaatgag ttgtacagta
     4201 gaatagttaa aaattcagat atgaaaggct acgaaacgct tttaaataca acaacaatcc
     4261 tagctggtgt aaatataaac aacaaagata tcacagatat aattattgtt aatataaaag
     4321 atattggagc tataaagcaa tatgttgcaa ggtttagaaa tttaaaaaaa gtaaatgtac
     4381 acatattcaa taaatacaaa gaagagtgta atgtctataa aatagaatgg ttggttgata
     4441 aaaatataga aaaagcaact atcttaaaag atgcttataa caaagtatct aaacataccc
     4501 taatgtttga aacggttggg ataaatgcta caccaattcg aattgattca aatgtttatt
     4561 actgtatgaa agacaattgt tacaaagtag ataaactgta tataaaaagc caaatttaca
     4621 gtaactatta caacacaaga acaatacaaa gttttaaagt tttattagaa gaatacttcg
     4681 ataatgttaa tataactgat gctaaagaaa ttgaaacaaa tgaaaaagaa ttaaaagaat
     4741 ataaaaaagt tgtaaaagaa attaaagaag caacaagaaa tattttaaaa gaacataaag
     4801 aaattttggt aggttataga cagattaaaa gcaattctaa gagcttttca ctaatgcagt
     4861 atcataatga tatgaaacta agttcaaaag ggtgcttaga ggcttacaga gcgtatgaca
     4921 tacataattt ggtaaagaaa agtaaaagta atagcatgtt agaactatat tctaactatg
     4981 tgctagataa taaattcagt ttagacctcg cttggaagtt agcaaataca gcaaatagaa
     5041 agcgtggagc aatattcaac aagttaaata ctttgatata cagagaatta aaagaggaat
     5101 atccagaatt tttaaatgat gaacttattc aagttacagt atttaattat atagacaaat
     5161 tatttggaat tggaacatct tatacagagt tgcatttaca agagttaagt gacgacttaa
     5221 gattgatttt aggagaaaat tggaacttaa caactaaaaa actgagtatc atattgaatg
     5281 aagtttttgt aatagaaaag aaaaaatata gaggtgggaa cagtttagaa aatatctttt
     5341 tttataaaaa tataaatcct aaactgttcc cactcgaagc tgaacgaatg caagttaata
     5401 atataaaaag atatataagc atagatgaca taaaaaaaga tttaaaatta gacgaaaaag
     5461 acaagagcct agaacatgct ataaaacata caaaagatag aatgttgaac tctttagatg
     5521 aagatgaaaa actgttgcta ctaaaaggtt ttatgtaaaa acatatggag ggatgaatat
     5581 gaaattaaga attgggatta tagataaata tgtggctgag gcaagttatg agttatcaga
     5641 acttttaatt gatgctttta ataaatatga tgaatttgtt gaggctataa gaggtggaga
     5701 aattcgcata gtcccattta atttgggatt tcaagctttg ctggaagagg attctactta
     5761 tgatgagtat gaattttatt acgatgatga ggatgataaa tgtttttttc atattaaata
     5821 tagaaatgtt aaagatgttg aactttcaaa agaacttttg ctagaactta taaaagttaa
     5881 tttgcccgca ggagcaaaat taattgtgaa caactagaaa tttgtgttta gatacaaaag
     5941 ccgggagtag gaatatatat atatataaat tcctactccc ggctttttga tatgagagct
     6001 gtagggttta aatatttgac cctacagttt ttaaatgtga gaaaattcaa agtaaattga
     6061 attgggatta ttttccacta gcaaaatttg ctaaaaggta ctattattgt agtataaatg
     6121 tttaattacg acaaaaaatc gtacatgtgt tcttgtgtaa tcgaacaaaa aagggtataa
     6181 ttaaagttgc aagttatttt tttcaaattt taagaatgta ttattctaat aaaaaatagg
     6241 gggatggttt tgttgaaaga ggaaataaaa agaatgatag atttaattgg ggacagagag
     6301 ttgttagaaa ttatttattt atatctaaga aaaaaaacta aaaataaatg agtacatata
     6361 aaaaagctat caaaaatgag atgatagctt ttattcttta gaaaatactt ctaaaatttt
     6421 caaaattgat tcgagttgct cgtctgttaa tttgctaaat tctaatactg ctttcgctag
     6481 tttttcgttt tcgtctattg cgcaaaaagc ctccgctttc acggagtttc tatcctcagt
     6541 gttatacatc tctcctgtgc cagttcttag ccaattctca tttaccttaa atagtgaaat
     6601 tattaatttt aaatcacttt cctttacctt cgtccttcca ctttctaaat tgtaaatctc
     6661 atgctttgtc tttcctaatt tttctccaaa ttctatttgc tttaacccct ctgatgacct
     6721 taactttctg attcgtatat ttatatcgtc tattatttcg ttcatttaca aaactccttt
     6781 cataaattga ttttacctta aaatattatt taagtcaacg taattatacg tccaaatggt
     6841 aaaatgaagg cataataaat ttcaatatag tattgacagt actcctataa cgtcatataa
     6901 tgtatctata gacgttatag gagtactggg aggtgttttt gtgaatagag aagaaatgat
     6961 ttgtaaaagt gtgaaattat atttaagttt aagcgaaaaa aaacaaaaag atattgattg
     7021 tataataaaa gctaataaca ttggaaatat cgctaatgaa cgtattttag acatagataa
     7081 attgaacgag gcagtcgaag gaatgaaaaa aatgatttgt taaaaaagtg tacttgacgg
     7141 ctacactaaa aaatctaatt taaaaaacga agggaaaagg tgagattatg tatattgaaa
     7201 atatcgaaga attaaaagag ttaattgaac tttttggagt tgtagaggca aagagtgaaa
     7261 gcgtagtttc atttggagaa gttgaaagtt tagattcttg tacagaagaa aatgcagaga
     7321 aagcattaga tatattaagt aagcataagc gagaagctaa gaacgaagaa gaaaatgaat
     7381 ttgtagaatt taaattgtgg actaataaag ttgaagagcg agaggaaata tttgctgata
     7441 ttgcttgttg tgagaaatgc ggaagaatat ttgctgactc tgaggaacta acctcgtttc
     7501 ctgtgttaac aagctatgat agaaaaagaa gtgtttttga acagttggaa actgttgcta
     7561 tatgtccaaa ttgcttaatg aatatgacta gaatatacga gtcgccattt tagttacaaa
     7621 gactagaaac gaaaagtaac aatgttagtc gtcaagtgcg tttttaatag tgtcaaatta
     7681 gttaaaataa gtatcttaac atatgtaaca aggagtaaaa caaatgaaaa aaatttcaga
     7741 aatgagtata ttggaaaaag ctgattttat tagaaatagg caaatagaac tgaaaaagaa
     7801 atatcaaaac aaagctaaag gagagctatt taatatagct tgccgagaga tagaagaaaa
     7861 ggaaaaaatg tgaaggggtg ttttgattga taggttataa gcttgtaaaa aatagtgagt
     7921 ttttaaaact taaagaagaa ttagaatcaa aaaaagatga attgaaattg aaagatgaag
     7981 aacttaaaaa gcgtcttgga gagctttctg agctgcattt atctaaagcg agtttgtata
     8041 tgaatttagg aatgactata atggaaaaag aattttataa ttcaataatt gaaaaattgt
     8101 tcgataaaga ttttaagaaa gctatcagta tttttaataa aactaaaaaa cttaggataa
     8161 agaataaaaa agcgactgaa atattactta gagtgaacaa agaagagaaa ataaaagaat
     8221 ttccttgtag gtataaataa gggggctatt tatgaacagg tttcgactag atgaagcgat
     8281 aagcataaca cgaagagata taaaagagct aagtggttat tcgaatgata taaaagaatg
     8341 taagaaggta aaagtcacaa ttattaaaaa aaatggaatt aaagtaccta ttactttttc
     8401 taatgaatta ttatatgact ttttgaagaa aggttttgaa ataagtttta aatcaatgtg
     8461 tgaagaagct gctgaaacag aaaaagaatt gcttagaatg aaagaaggaa gtgttagaaa
     8521 tgaataaaat gaatgttact caagcattag aaaaatttga tagtttatta gataaatata
     8581 atgatttacc cgattatgtt tatacgcttg aatatagatg taaattttat gaatggatta
     8641 gggcacttga aagaaaaaaa gaacttaaaa attacaaaat agttaatgtt ttaactgctg
     8701 aaagaaatag agaaacagct ccgttttggg atttagaaaa ggatgtggca aaatggataa
     8761 gaaagggaaa gttttaaaaa tctgtggttg gtgtggaaaa gcattttttt ctgatgataa
     8821 tggtaaagtt gcatattgtt ctaataaatg caaaagtaaa agagaaaaaa gtttgaagaa
     8881 agagaggttc aaagatgaat tttaaaatga ttgctaacat accaggtagt tggacagttc
     8941 aaaaacaatt tgaaaaagta ttagaagaaa ttttagaact taaagaagct attgcactgg
     9001 aagacaataa gaaaatatta gaagaaggtt tagatgtttt tcaagcaatt cttaccttat
     9061 ttaaaataat tggtatacat aacataagag aaggattgaa agagcataat aaaaaactaa
     9121 gaagaaggaa atggaaactc gaaaaaatag attaaagttg aaaacataaa tagatgatat
     9181 ttactttaat tattaaataa ataaggtata aataatttat attaatagat tttatttgaa
     9241 cttaaaaaaa tgaagtcttt agataaaaat acaatgtaaa aatacaaaat attttgaaaa
     9301 ttatagagct attgaaaata ctagaaattg tataactaat cccaaaagct aaatttaagg
     9361 attagttagg tatttataac aaaaagtgta agaggtgcaa aaatgaaaat aaaaaaagag
     9421 tatattgaca aagttgaaaa tatattaaaa atgttaggag atgaatatag aaagttaaga
     9481 gtattaaaaa aagaaatagc aattcttaaa cacaaagaaa actatagaga aattaattat
     9541 gaagaattgg ggtttaaagt gcaaaaaagt gtaaaaagta tagatgacat ggttataaca
     9601 atagaggatg ttatctacaa caaagaaact gaaattgaaa ttatagagcg aaagctagag
     9661 ttttataata tttacttaaa agaattatca gagcttgaac agaagatgat agaattaata
     9721 tatttttata attgggatga aaaactacct atcacaaaaa tagcttatga attaaattat
     9781 gatagaagta gtctttataa caaaaaagct attgctatta ataaaatagc tttaatgata
     9841 tatggtgatg aagctttgga gtaaacatta tttttacaga aaaaagacta tttttatact
     9901 tcgtttctaa agaaagtatg ttagataggc ttttttattg ctaaaaaagg aagagggtga
     9961 gttgattggt tgaattgaaa aaagagtaca ttgatgaagt tataaaactt ttagatgaag
    10021 ttagagaact tagagtaaga aaagaagttt taaatgatga aatagaattt cttaaaaaga
    10081 atgaaaagct tagtagtatt aattttaatg aacttggttt tccagtgcgc tccggaagtt
    10141 atagtataga tgatatgatt ataaattcac aggagaaaat ttatataaaa gagactgaaa
    10201 ttgaaattat agatagtaga atagaaatga ttaatattta cacgaaaaga ttgagcgaag
    10261 aagaacagga gattataagt cttagacatt ttgactcaaa aataaattcc tacggggaaa
    10321 tttctgaatt attaatgatt tctaaaacgg tcgttcagag gaaatatacg gacgctttga
    10381 ggaaaattgt attgatgaag tatggagaaa aagcgaaaaa agatagggaa taaaaaggac
    10441 taaaaaaggt caacacaaaa cttttgttac atgttataat tgtattgtgg aaaattaaat
    10501 atgtttctac ttcaaaagct tgtgagaaaa aactcatgag ctttttttat tctcttttga
    10561 aagggggtat tttgattagg agtaaaaaga gcatcgaagc ctatcaggcg tacacaagaa
    10621 gtgctagata ttcaagaata tctaagatat aaaagttata gaaactatgt gatttttatg
    10681 ctagggataa caacaggata tagagcagga gatttagtta aactaaaagt tagagacgta
    10741 agggaagctt taaaaagaca agaatttact attatggaag gtaaaaaagc taatagtaaa
    10801 aacattaggg aaaagaacag aaaacctcgt acagtagaaa taagacctag gattgcgcaa
    10861 attttaaaga aatatataaa agataagcat gactatgaat acatgtttcc atcgagaaaa
    10921 agaaaatatc ctcacattgg tgttgaagct gttagcaaag ctttaaaaga agcaggagaa
    10981 tattttggtt tatatgatat aacagcacat agcatgagga aaacttatgc ttataaaatt
    11041 tatattgata gcgaaaaaga tattgttgca gttaaagaat tgttgggtca ctcttcgata
    11101 gaagaaacaa aaatgtattt aggtttagat aaagaattgt atcatcatta cagtgagtca
    11161 ttagacgact ttgtaaggtg atattttttt atttgtctgt ttgaatgtct aaaaatttgg
    11221 tgtagtgata ttcaaggtat caaaatcact atataagaag taagaaaaaa atagattgaa
    11281 tgtctggttc tctaagaaaa taagacgttc aaatgaagaa atacgaacta tatttaatta
    11341 gtttttaata atgttcgtat agaaaaagag gtgctttatg aagaaaatag agttggatga
    11401 taaagagatt aaactgatta tttcagcatt agatttaaaa gtttctcgca acttaggcaa
    11461 agcttataaa aacttcccat atgcttttga tgaaaaagaa gagtataaga gggatgtggc
    11521 aactatggag cttttgattg ataagttttt aagtaagctt aatgaggtag agtgtgaggg
    11581 agtgcttata taatggctag agagtttagt cgaagctttt ataatagcaa agcttggaag
    11641 gagtgtaggc aatcaattat taagaaatat ctaggcttgt gtgctgagtg tgggaagcta
    11701 ggagaagaag tgcatcatat aaaatattta actcctgcta atatacatga tgttgagata
    11761 actttaggtg aggagaattt aatattgcta tgtaaagact gtcatagtaa aaaacataag
    11821 agtaagaaag acattactag aacagggtta aaatttaatg aaaaagggga attgatttcg
    11881 atttagaaaa aaaatagtat atcccccctt aaaaacgacc ctgggggctg atttcaaata
    11941 ccgatgtccc cacatcaatt ttcctccgca tgaaaaaatc agaatgggag gggggttatt
    12001 taaaataatt tacgaacaat tagagaaaga aaaaaagata aaacaagagg taagcagatt
    12061 aaagaaaaac tataaagatt tagaaaaaga aaaagttaaa attttggatg ggttagtaaa
    12121 tgaagcagct tttttaaaaa tatctttaga agaaactaga gaaattttga caaaagaggg
    12181 tttgactgaa attttcaagc aaggcaagca ggaatttgaa agggaaagac ttcaagttaa
    12241 gatatattta aattttatga aactttattc taatgtcatg aagcaactaa ttgatattat
    12301 tccaagcgat atgaaacagg aagaagagga cgaacttatt aagtttataa aaaaaggtag
    12361 acttaataaa tgacctacat tgaagagtat tatcaaaaaa tattaaatgg agaaatagtt
    12421 gcttgtagca gaattaagca ggtgtacaaa aagcttgtcc aagacctata taatccaaaa
    12481 gaaaattggg tttttgatga agagcttgct aatagaccta tcgagtttat agagactttt
    12541 tgtaagcaag cgcaaggtaa gttgggcgaa cctttgaaac ttgaattatt tcaaaaggct
    12601 aaacatcaag ctgtgttcgg ttttgttgat aaagagactg ggtttagaaa atatcaagaa
    12661 gtacttgata ttcgaggtcg taaaaatggt aagactacag aattggcagc agatgaatta
    12721 tttatgttaa ttgcagacaa tgaagggtcg ccagaggttt ataatattgc aactaaatac
    12781 gaacaggcac aaaaagggtt taaagagtgc tacaaaatgg tacagcaatc taaaatttta
    12841 tctaagcata ttaagaaaag aaaatcagac ctctattttc acgctaatta tggtttttta
    12901 caggcacttg ctagtaatag taatgggctc gatggattaa actcgcatat ggtaactata
    12961 gatgaattgg cagctataaa aaatagagat atttacgacc taatgaagca atctatgagt
    13021 gcaagaaatc aacccctttt aaattgcatt accacaaatg gttttgtgag agagggtatt
    13081 tttgatgcac aatatgagta tgcttgcaat gttttagatg gaaaaataaa agatgataga
    13141 tttatagctt ttatttatga gctagacgac aaggatgaat gggatagaga agaatgctgg
    13201 ataaaagcta atccaggttt aggtactata aaaaaacttg attttttaag agactgtgtt
    13261 aataaagcta agacagaccc aagttttaag cctactgtca tggtaaaaga ttttaatatg
    13321 aaagaaaact ctgcgactgc ttggttgagg tgggatgagt taaacaatga aactaaattt
    13381 aatgtaaatg aaatggaatt tagatatggc ataggttgtt ttgacttagc tgaaactaca
    13441 gacctagcat ctgctaaagt tttattaaag aaaagatatg atgataatat ttatacactt
    13501 tctatgtatt gggttccgtc tgaacgatta aagcaaaaag ttgatgaaga taaaatacca
    13561 tacgatttgt gggaaaaaca gggtttatta agggtatgcg aaggaaataa aataaatcca
    13621 tatgaccttt tattatggtt tagagaaatt aaagaagagc atgatattta tattccctgg
    13681 attggatatg acccctggca tgtagattcg agtctgcttt tagcttatga gaatgaattt
    13741 ggaaaagatg caatgattaa agttaggcaa ggagtttata ctttatcagc ccccatgaaa
    13801 gagttaagag ctgatttaaa agctaataaa gttatttata ataataaccc tatcgataaa
    13861 tggtgtctta gcaatataga aataaaaaca gatataaatg gaaatataca gccaataaaa
    13921 ggtatggaca gaagacgacg cattgatgga ggtgtcactt taattatagg ctatgttgtt
    13981 ctaaaagaaa aaatgtcaga atatgaaaac atgatttaag taaggtggtg aaaaatgaac
    14041 atatttaaat ctaagaagaa aaataaagaa gctcctgaaa gaattgtaat ggaactcatt
    14101 ttagatttgg gaaacgggtt ttatagttgg catggcaatt tatatagaag cgatattgta
    14161 agaagtatta tacgaccgaa ggctaaagct gttgggaaaa tggcagctaa acatattaga
    14221 agtaatgaga ctgaatttaa aactaatcca gagccttaca ttaaattttt gcttgaaaat
    14281 ccgaacccat ttatgagtgg gcaaatactt caagagaaga tggttactca attagagctt
    14341 aatagcaatg cttttgctgt gattattaaa gatgatgata atataccaac tcaaatttac
    14401 cctttgaatg ctttaaattt tgaagctatt tatgaagata gagttttgtt tttaaaattc
    14461 ttacttagaa atggaaaagt agttacctat ccatattcga acataatcca tttaagaaaa
    14521 gattttaacg aaaatgattt atttggaaca cctccaacta aagtacttaa agcgcttatg
    14581 gaagttgtaa atacaacaga ccagggagtc gtgaaggcta ttaaaaacag caacacaatc
    14641 aaatggttat taaaatttaa aacatcactt cgacctgacg atattaaaaa agaggtcaaa
    14701 gagtttgaaa aaaattactt acaaatagac tcggaagcag gcggagctgc cgcaactgat
    14761 tcaaaatatg atgctgaaca ggttaaagct gagagttatg ttcctaacgc cgcacagatg
    14821 gacaaaacta cacaaagatt atattcgttt tttaatacaa atgagaaaat aattcaaagt
    14881 aaatataccg aagacgaatg gaatgcttat tatgagtctg aaattgagcc agtaggattg
    14941 caactatcta aagaatatac gcaaaaatta tttactagaa aagaaagaag ttttggaaat
    15001 gaaattattt ttgaagcttc taatttacag tatgcaagta tgtctactaa attgaatttg
    15061 gttcaaatgg ttgatagggg ttcgcttgct ccgaacgaat ggcgtaagat aatgaacctt
    15121 tcgccaatag agggcggaga caagccagtt cgccgattag atactgctat tgtggaaggg
    15181 ggtgattaaa ttaaatggct agtgataatt tgaaagaatt tttaaaagtt aaaagctcta
    15241 cagaaacaaa tgcagatttg tttttctatg gtgatattgt ctgtgatgag tgggatgcct
    15301 ggacagaaga agaccagtat ccacttgcaa taaaagattt tttagcacaa gaacagggaa
    15361 aagatttaaa tatttatatc aattccggtg gtggttctgt atttgcaggt atggcaatat
    15421 ataatatgct aaaaaggcac gaaggattta aaactgttta tgtagatggt attgcagcga
    15481 gtattgcgag tgttatagct ttagcaggtg atagagttgt aatccctcaa aatgcctatt
    15541 ttatgattca taagccttgg ataggtttat gtggtgctta taattcagat aaattaatta
    15601 aggcggcaga ggatttagac agaatagagg aaggtatttt aaatgtatat caagataact
    15661 taaaagaaga aattgatatt gaagaaataa aagaaaagct aagtgaagaa acttggttta
    15721 ctggtaaaga agcatcaaat tattttaatt ttgaagttga tgagaaaaaa gaggttgctg
    15781 cttgcgtgag cgattatttt gataagtata ataaagtacc tcatgcttta aaaaataaaa
    15841 tagataagac tagtaataaa aaagaaaata ataataaaaa aagagttcag atgaaactgg
    15901 acttattaaa attagggggt ttaaatgact agagaagagt attttaagaa aagacaagaa
    15961 atgatagacg aagcacaaaa attacttgat gatgaaattg gagaagaagg aacaggagaa
    16021 gaaaagacgg aagaagctga aaaaatagct aataagataa aagctttaga tgaggaatat
    16081 gaaagaaatg taaaagctag ggcgaattta aaagcattgc aggatgatgt caaaatcgac
    16141 cctactattt ttaatttaac taataacaaa ggtaaaatag aaggtataga agacacaact
    16201 gttaaggatg aacaagaaca atataaaaat gcttgggcta aagatatgtt aggaaagcag
    16261 ttaaattcag aagaacagga gatatttaat agtattaact cagcatatag agcggaagtt
    16321 caaacaagcg aaaataatac tattttaatc cctaaaactg ttgcttcggg tatatggaaa
    16381 gaaattggtg acatgtatcc gttattcgga gatgcttctc caacttttgt agcaggtgat
    16441 ttgacgatta tagcagaaga agatggtggc gatgatgctg cgtggtatga tgaagaaaca
    16501 gaagttaaag aggatggtta taagctaaag gaaataacct taagaggttg tgagcttgca
    16561 aaagatataa ctgtgtcgtg gaaattgaaa aaaatgagta ttgatgaatt tgttccatat
    16621 ataactactt tattggctga aaaaatgggt gcagcattgg cgaaagcgat tgtagatgga
    16681 aaaggaaaac cgggggaaag tgattctttt aaacctcagc cgcttggaat aaaaactgct
    16741 ttaagcaagg aagttagtaa ggcacaaata atagaatata ctgacaagat agcttataca
    16801 gatataacga aattgatgtc tgttttaaag aaatggagca atggagcttg tatttatgct
    16861 aatagcacaa ctatatggac acaattagct gaaatattag atacaactgg aaagcctatt
    16921 tttatccctg acgctgcaaa tagtgacgga gttggaagga tgtttggcag ggttgttaaa
    16981 atggatgaca gcatggcaga tggcgagatt cttgctggaa atatatcgaa aggttatgcg
    17041 ataaatataa atgagaatgt aactttatat acagatgaac atgtaaaaag tagaaaaaca
    17101 gattatttaa cttattcatt agttgatggc aatgttataa gtaataaagc ttttggtatg
    17161 atagttaaaa aaactagtgc agttgcgaag taggtgtttt gaatgattgt gtcattagaa
    17221 gaaataaaag aatatttgag attagaggca gattataaag aagatgataa tctgcttttg
    17281 tctcttctta aagcagcaga ggaggattta gaaaatcgaa caggaaaagt ttttaatgaa
    17341 actaacaaat ctgaacttgt tagtttgtat gtaaaaatgt atgttgcaga gcaatatgaa
    17401 aaaagaggtg caacagaaag taatagcgaa aaagttagat ttgttttaga aagtataata
    17461 tctcaaattt ctatatgtag taggtattaa aaaatggata ttggaaaatt aactcaaaga
    17521 atagatatac aaatttatgg agaaattgaa aacgacatag gagaggttac aaagggatgg
    17581 gctacttata aaaaactttg ggctaacaaa tcgttgctta gaaatagtaa taattatgtg
    17641 ttagataaag aaaatataga gtattcttac agatttaaaa taagatatag aactgatata
    17701 acagaagcta tgagaatagt ttgtaatgat gttgtctatg atataaagca tgtaaataat
    17761 ataaaagagc taaataaata tgaaacaaat attgattgta ttctttataa agaaggtgtt
    17821 tacaatgagt aatacagatt ttaatatgaa tggattagat gattatacaa ataaactatt
    17881 taagcgtatt gtaaaagaat accccaagaa agctgaaaag cttatgaata tcagcttagg
    17941 aaaatgcaaa ggagaagcta ttgcaagaac tccgaagtca gataaaaagc ctaaaaaata
    18001 caaaagagct aagcacatga aagataattg gaaaactaaa acgcagtcta aaaatgggaa
    18061 ttttgtaggt gttttaaaaa ataattctcc acatgcgcat ctaatagaaa atggctgggt
    18121 aacaaaaaat ggaggctatg tcgaaggaaa acatatgttg caacaaacga tggagcatca
    18181 gagagcgaaa attgataaaa gaatagaaaa aatggttgat gaaactttta atctttagag
    18241 ggggtaagag tgttaaaaat tgtttctgta aaaaaagcta tagttgaaaa gcttaagtct
    18301 ttaaatataa aaatagtagc aaatgaaata aggagcgggt ttgaaaaacc tgcttttttt
    18361 attcaaatca ttcctattga aatggctagc gacccaagtt tttcaaatag tacattactt
    18421 gttaatatac attatttttc taaagaaaag acagaattag aaaatttaaa aatgattgat
    18481 aagcttaata tattatttca agattgtatt ttagaaattg aagggggcaa attgactata
    18541 gaagaaaaaa gtgtagaaat atatgagaat gttttacaat acaaatttaa tttgcaagta
    18601 gttgaaatta tagaagaaga cgaaagtaaa tatgagctta tgaaagagct tgaaatgaat
    18661 atttaaaaaa ggaggtttta ttttgggatt accaagtgcg ataattgagt ttcaaagacg
    18721 ttcaaggact gttaaattta gaagtcgaag aggtattgta gctttaatac ttaaagattc
    18781 aacagctata aagaaatctt attctatcga ttttttaacg gatataaatg aaactgaatt
    18841 tacaaaagaa aattatgatt atataaggct tgcattttta ggaaaaccta gcaaggttat
    18901 tattgaagtt attaatgatt cagttgattc tgaaaggtct ttagacgatg ctttgaaagc
    18961 tttaagggag aataaattta actatttagc tattcctttt ataagtgaag aagttgacaa
    19021 aactaaaata gttaattgga taaaaacagc tagaagggaa aaagagatat acaaagctgt
    19081 gttgccaagc gttactaatg ctaacgagaa ggcaattata aacttctcga caacaggaat
    19141 aaaagttggc gaaaaagttt atacaacagc agaatacaca gctagagtcg caggcatttt
    19201 ggcgggcata tcgctttcag agagctgcac atattttgtt ttagatgaag ttacagagat
    19261 agaacctact gaaaatcctg acgaagctgt agacgaagga aaactaattt taataaataa
    19321 taatgggata aggatagcta ggggcgtaaa ctcattaata actttaagca aagaggatac
    19381 agaagacttg aagaaaataa aaatagttga agctattgat atgatacaag atgatattct
    19441 tcaaacctgg aacgaaaatt atgttggtaa agtaactaat aaatatgata ataaaatatt
    19501 gtttttatct gctgtaaaca attattttaa agagttgcaa cgtgatgaag tacttgacaa
    19561 cagccaagaa gcttatgcac agatagatat agaagcgcat aaaaaatatc taaaagaaaa
    19621 aggcattgat tatagcgaaa tgactgaaca gcaaataaaa gaagctaata caggttctta
    19681 tgtttttata gaaggaaaca tcactgttac tgatgctatg gaagacttga aatttaaaat
    19741 atatatgtaa agaaggtgaa tagatgggca aagaaaatat cgtaggaagt agtcaaattt
    19801 ccggcacatg gggaaagctt tggtgggatg gaactttaat tgctgaggtg cttagttttg
    19861 aagctaaagt tacagcaaat agagaagaga ttcagtttgg aatgagtaaa gattctaaaa
    19921 taacatcgct aagcggcgaa gggactgtaa aacttggaaa agtgtattcc agggggaaga
    19981 aaaaattatt ggaagcttgg aaaaatggag aagacccacg aagcacactt acaagtaagg
    20041 tgaaagaccc tagcacacct gggaaacaag cagaaacagt cacaattaac aacgtgtggt
    20101 ttaatgaact agctttatca cagtttgaaa agggcggaaa aatcgaagaa gagctaagct
    20161 ttggatttac accaaacgat tcagacgtga tggacgaaat agacgaaatt taaaggatag
    20221 tttttactat ccttttttat ataataggag gattttaaaa tggataataa aaaagaaatg
    20281 gtaacaatag aggatatttt aagaagaaaa gaatattttg caaagaaaag tgaagaaacc
    20341 aagcaattat atattccttc gcttgatgga aatatagaga tttcaaagcc ggacaggatg
    20401 ttgtgtcttg atgcaataga aatggaagac gcagtcgaag gagataaata ttttgtatat
    20461 gaaattgtta aaagtccgaa tttaaagagc gaaaaattgc atgctgaatt tggatgtaaa
    20521 gataacccac ttgatatagt cgatgtatta tttgaagcag gtgaaattac tgatattgtc
    20581 aagattgcaa caaagtttgc agggtttggg gttgtagagg aaattgaaga cttaaaaaac
    20641 taattaaaag cgatgtggaa atgcaaatga ttagtcatta tctagaaaaa ggtgtcgatt
    20701 tagataaatt aactaattta aatatgatag aaaaaaattt tcacatcgct tgtatgctat
    20761 atgaagaaga agaaaaaata aaacttattt ctgagctaat aggtgctatg tttggaggtg
    20821 taaaaaatgg ctagaaggca tataggtgca gttatatctc taaaagacaa tatgagtgct
    20881 accatgaggg ggattagaag agagcaaaaa caatttcaaa acgaggttag acggacacgt
    20941 aacgagatgc gttcggcaag tagagagcgc atgcgcataa ggatggatgc aactcctgca
    21001 cacaggacta tacaagattt aaggcgaaaa tttgcacctc ttcgtactaa actcgtaaaa
    21061 gctgttgtta taaaagattt agcaactgaa aagatagaaa gaataaaatc gaacgtaaaa
    21121 tcttttggaa aatttattgc aagacctgtc gtaaaactta aagatgaaac aaaaggaatg
    21181 attgataaaa taaaaaatcg gcttactagt ttatcaacta tagttccagt tggtgctgca
    21241 gttggcgctg cgggtatggc tgttaaaagt ggtatggaac tagagcaaca acaaataagt
    21301 atgcgtcatt tcatgggagt tggaaacaaa ggaaagtcta gcaaagagct tgatggaatg
    21361 agcgcaagct atttaaaaga tttaagaaat aatgcaaatg cgacaccatt tgaaactgga
    21421 gaagttatat cagcaggaac tcgttctttg caaatagcgg gtggaaatac aaaagatgct
    21481 atgcagatgg ttaaactagc agaggacatg gcggcgctaa atccaggcaa gaccgttgga
    21541 gatgctatgg aagcacttgc ggacatgaac attggagaaa tggcaagact tacggagttt
    21601 ggagttaagg caagcagtac agacgaccca aaggaagtac aaaagaaact tgaaacaatg
    21661 tatgcaggag gagcaaataa gctcgctgaa agtggttcgg gacttctttc tacgataatg
    21721 ggtaagttaa agtctaatat cgcagacatt gggcttggca tgttagaacc tctcaaaccg
    21781 gttatgactg gcttaattgg atttatagac caagctagtc ctaagatatt agaggtaggt
    21841 acaaaaataa caagtggaat aggtatggcg attggatgga tacagcaaca aatgccaact
    21901 ttagctccaa tttttcaaac agcttttgga gctgtatctt cgattgtatc aactgttgcc
    21961 ccaataattg gtcaagttat aggagcttta agccctgttt ttataggatt gctttctgtt
    22021 gcttcttctg cattgtcagg gattgcttct gctgttaaaa ctgtagctcc tgttgtaagt
    22081 tctttaattt ctaagttagc gccaattttt ttaaatgttg gaagtacttt aaaatctatg
    22141 ggtaagattt ttaaaaatgt ttttgatagt gttatgaaaa tagttaaaaa agcgtctgat
    22201 ttcataaaac cattagtcaa tggaataata ggtgcaacaa aaggcattag tgatggagtt
    22261 agttgggttg ctggaaaact ggctggaaat gcaactggaa cgaaatattg gtcgggcgga
    22321 ctttctgtcg taggcgaaca tggacccgaa cttgtatcta tgccacgtgg tagcaaggtt
    22381 tttacaaatg cagaaagtaa gtctatgatt aataaaagta ttccaaattt tagacaagtg
    22441 caaggagaaa acacaaatta taatataaca attcctaaaa ttgctgaaca aatagtaata
    22501 agagaagatg ctgacattga aagaataaca tcaagcttaa taaaaaaaat acaaatggcg
    22561 aaaatgggcg gtgttgttta atggaaatgt ggcttagaca atcgaatgat tcttttagat
    22621 tccctatact tccgacctct tttgaaataa gcggaaatat aaatacaagt acaacaaatg
    22681 tgttgaaact tggagaagta attgtttgtg ggggtatggg acttagaaca acagagataa
    22741 acagtttttt tccaggtgaa caatatcatt tttgcaatta taaagatttt ccacaaccat
    22801 atgattgtgt aaataaattg aaaaagtgga tggagcaggg gttaatttta aggtatataa
    22861 taactgaaac tgatgtgaat atggaggtta ttattgaaag cttcaaacat ggcaagcagg
    22921 atggtacaaa cgatgtttac tttacattga gtttaaaaga atataaaaga attcagatac
    22981 ctaaagtaaa tactaataat gatgaaaagt tatcttctgt aaaagatgtg ccactgacaa
    23041 aaggatttga ggttaagaaa caaagaactc ataaggtaag taaaggtgac agcctttgga
    23101 gtttggcaaa aaaatattat ggtaatgggg atttgtggaa gaagatttat gatgcaaata
    23161 aaaaattaat taaaaatcct gacatcatcc aagatggttg ggtattggta attccatagg
    23221 ctggaggtga tttataatta acaatataaa gttaaaagta cacataaaaa atggcaatat
    23281 ctatgatata actgatatag tagaaaaagt tacatggagt ggtgattata agtcaccatc
    23341 aaggacatta gaattttcta tagtacagtc agcttctgat attaatttta gaaagataga
    23401 tatacctata gctagtacag tttgttttta tgtggatgat aaagaactct atagaggaat
    23461 gataattaat aggtctaaag actctagcaa caatagtatt agttttgtat ctaaagatat
    23521 gggattcttg ttaacacaga gtgaagtgtc atataacttt aaagataaat tagttgaaga
    23581 tattgcaaaa caggtattta atgacaataa acttgcaata ggaaatatac ctaaaactaa
    23641 tgttaaatac actaagatgt ttattggtgt aactggctat gatactataa tgagtgcata
    23701 tacagaagct agtaagacaa cgaagaaaaa gtatatgata gagtctaatt tagataaatt
    23761 taatgttatt gaaaaaggga ttattacact aaatgttatg tttgaagaag ggtctaatct
    23821 tattaacacg agcttttcag agagtatgga gaatgtaaaa aacaaggtat tagttgtaga
    23881 ccagtatgga aataaaataa gtgaaaagat agacgataaa atttttaaag atgttggagt
    23941 aataatgcaa aaggttatac agcaacaaga aaatagtact gtagatattg aaagtgagtt
    24001 caagggaata gaacagactt gcagtttgaa agggtatggt gacgtgactt gtataactgg
    24061 cagaggtgta aaagttaagg atagttacac aggtcttaca gggctatttt atatagacac
    24121 agataaacat aattgggaca gtaacggaaa ttatgagata gatttagatt taaattttca
    24181 aaatatcatg gatgaaaaga cagcaggaca ggacgaacag aaggaagaaa gttcagattt
    24241 gaatggagaa ggtacactaa atggaagaga agtaaaagca gaatttacag cttattatcc
    24301 gtctaataac cctatggagg gtggttatta tcaagctatg gatggtaaaa gacttgtacc
    24361 ttcaaacaat acttgtgctg cacctagtaa acttaaattt aaaacaaaaa ttcaagcaaa
    24421 atgtcctgga actaaaattg atggtaaaac ttatacagta acagacagag gaggagcgat
    24481 tggcttaaaa aacggagtgt atagaataga tatattaatg tctagtgaaa aagaatgtaa
    24541 tgattttgga agaagaaaag gaacaataat aattggagat ggcacaggct atacaaatgc
    24601 aacaggaaaa gctaaagaat tgataagtat agcaaaaagc aagctaggct gtaagtatgt
    24661 ttggggagct actggtccaa atacttttga ttgtagtgga ttcactcaat ggtgttacaa
    24721 aaagataggt ataaacattc ctagagtatc aagaggccaa ggaaaagcag gtaaagcagt
    24781 aagtaaagga agtttacaac caggagattt agttttcttt tctagcaaag gagcaaatgg
    24841 aacaatagac catgttggta tgtttattgg aaatggagaa tttattcatt ctccgcatac
    24901 tggtgatgtt gtaaaaataa gtaagttaag tggtagctat tacactaaaa attatgtaac
    24961 agctagaaga tatttataaa aaggtggtga tatagtgtct gatccaataa atgaatttat
    25021 aggaataata agagaggaag gaaaacatta caatgaacct tctttttttg ttggaaaaat
    25081 taaaagcaaa ttaccagatt taaaaataga gataaataac atcgtattag aaaaagaaga
    25141 tattttgata gatagttgga tgcttgatag acagatagaa tcatttgata cagaaacaaa
    25201 tcaagaacat caacatgaag taaaaaatcc atttatagat acttttgaat ctggagacat
    25261 agtaataatg ttcaaaatag gtgataaatt tgctgttgta agtaagttgg tgagtttata
    25321 atgagtacaa tatttccttt tataggtgtc ccagaagatt atatcttgcc taaaacggaa
    25381 gaattgccaa tctttcgtga agtggcctgg gattttgaaa aagatgaacc tattttagaa
    25441 aatggagatt ttaagattat tgaaggcaat gaagctatca aaatttgggt gtataaatgc
    25501 atcaaaacaa atagatatga gcatgaaatt tatagctggg gctatggaac tgaattatct
    25561 gaacttattg gacagaaata tagtaaagga cttacagaaa gtgaagctag tagatatata
    25621 aaagaggctt tattagttaa tcaatatata ttagatgtca atatcaagga tacaaaattt
    25681 acagatgatt tattaagtgt aaatatagaa atttcgacga tttatgggga ggtagaagtt
    25741 aatgtatagt agtcaaactt atgatgtcat taaaaataga actctatcaa atatagattt
    25801 agatatctat aagggtgagg gttctttttt aagtgatatg gtatctccaa tcagtacaga
    25861 actcgcaaaa ttctatatag aactttcata tcttcataaa aaagctttta ttgaagataa
    25921 ttttgatgat tttcttgata aacgggtaaa tgaatttgga gtatacagaa aactaggaac
    25981 agaagctaca ggagaagtgg tattcgaggg aaaagctgga acagttatac caaatggaac
    26041 aattatatct tacaatgagt tattattcgt agtaattaaa gatatagtaa ttagttcgga
    26101 aatcgaacaa aatacaagcc ccgtacaggc tttagaaatt ggaattagat ataatatacc
    26161 tgcaagtact gaatttaagc tacaagacga aataaacggt ataagtaaaa tatataataa
    26221 tttagacttt aaaggtggta cagaaataga aacagacgaa gaattaaaag agagattcta
    26281 taaaatccaa agaaatcaag ctacaagtgg aaataaagct cactatgaag aatgggcttt
    26341 agaagttgaa ggagtatata acgctaaaat ctatccgaga tgggatggtc cagggacggt
    26401 aaaggtatta atatttggag aaaataatca agctgttgac acagaagtaa ttgaaagatg
    26461 caaagaacat attgaggaag aaatgccaat aggtcctgcg ttaaccgttt taactccaag
    26521 cgttttagat ataagtataa gtgcatctat aaaattagaa gcgggatata cattagattt
    26581 tgtaaaagaa agcttcttag agagtattaa tagttattta ataaatgtta ataaagaaat
    26641 aatttacact aaagtaagtg caatacttgc gtctattgag ggtatacatg actttagcaa
    26701 tttactgtta aataacaaag ctgaaaatat agtatttgaa gaagacaaag ttccaagtgt
    26761 tacgacccta gagtttagtg aggtggtagt ttaatgaaat taattgataa gctaccttct
    26821 ttttacaaca ataatgttac tagtaaaata caagaagctt atgacataga actagaaaca
    26881 cttagagaaa cttatgacga tacttttgac cagttctttg tagatacagc cacttgggga
    26941 ttggattatt gggaaaatat tttatctatt aaaaatagat ttgatttaaa tatagaagat
    27001 agaagaagta atataaaagc aaaaatgaga ggtaagggta caactacgat agaagttata
    27061 aaagctatat cagaagccta cacaaagact aatgttgatg tagaagtttt tagcaatcta
    27121 tttagtttta cacttagttt tataacaaat gattgtagtt ataacactat tttagagtta
    27181 gacaagaaaa tagaagaaat aaaacctgcg catttagaac ataaatttga gagagtttta
    27241 tttgataaaa gtagacttta cgcaggtgcg acgattagtg caggggaaac agttacaata
    27301 tatccttatg tacctagaga tttagaaagt tttggagaaa tagctatttg cagtggaaat
    27361 gatagagcgc tagaaaaagt aacattgtat cctaaaaaat agaaatgagg tgataaaatt
    27421 ggcagaacaa caatatttta ctctagtaac tgacattggt aaggcagcaa tagcaaatgc
    27481 aagtgttaca ggtgaaaaag tagattttgc aaagataaaa gttggagatg gaggagggag
    27541 ttcttatact ccaaatgaga gtcaaacagc actaaaaaat gtagtttggg aaagcacact
    27601 tgaacatgca caagtagata aagacaatcc taactgggta gtaatacaaa aattcatacc
    27661 tggcgatgtt ggaggatttg aaataagaga agttggtcta ttcgattcca aagaccaatt
    27721 attagcggtt tctagttacc caacaacata taaacctgaa gcagattcgg ggactgtaaa
    27781 agaactatta ataaaagtaa tattagttgt atctaatgta gctaatataa atctaaaagt
    27841 agaccctact gtcattctag caactttaaa agatttgcag gacctagact ctaaaattga
    27901 tacaactaaa acagaattaa caaacagtat agaaactgct aaaacagagt taaacaacaa
    27961 aataggagat acaacacaac ttgaaacaac ggataaaact agtcttgttg gtgcattaaa
    28021 tgaggtaaaa actagtgtag atagcataga aacaacagca gagaaaacaa gttataataa
    28081 tgcaacaagc aatcttactg ctacgaatgt gcaaggggcg attgatgaag ttgttagaaa
    28141 gatagaaaat ttcaatgagg ttaatatatc tatacaaaat gatatgttac ctatttaaga
    28201 gaggagagtg agaaaatgca gactgaatgg aattttgatt ttaaggcaga agcacaacca
    28261 attactctaa aagcaggtaa atataaatta gagtgttggg gagctcatgg aaaggtttgg
    28321 ggtggagatt ctcaatctag tggaggatac tcttatgggg aacttacatt aaaaaaagaa
    28381 actacattat atgtatatac aggtgctact ggttctagta ataaatatga agaatttaca
    28441 tttaatggag gaggacttgg tgttaatagt ggaggaggtg gagcaactga tataagactt
    28501 gtcaatggag attggaataa taaacaaggt cttttgtcta ggataattgt tgctggtggt
    28561 ggtggaggcg catttagtaa aactcctgct ggcaaaggtg gtggttttaa aggcggaaat
    28621 agtactaatg atgataacag ttcgatgctt attgtacctg gtggtacaca atatgatgga
    28681 ggtagaggtt attgtgatga atgggatggt gtttttggtt gtggtggagg ttctattctt
    28741 ggtttagaac aaggtaaata cccttataat tcaggtggag gtggatggtt tggtggtgca
    28801 ggtgctagaa atatttcaag tggtggaggt ggaagtggct atgtattaac taaagatagc
    28861 tataaacctg ttggatatat acctacatct gaatattggt tagaaaatgt tggtagtatt
    28921 actgggggta atactgctaa agtaaatggt tatgctaaga taacattact gcaagcatta
    28981 ccatttttaa cagtatcttc ttataattcc acacaagcaa cattcaaagc tgcccacaca
    29041 gaccctacat tattaactaa aatagaatat tttatagatg atatattaaa agaaactata
    29101 acaaccgatt taactcttga aaaaacaatt aactatacat tagaagataa tgcactgcac
    29161 acacttaaaa tagttgttac agacagcgct aatgctacag cagaaaagat attaagcata
    29221 agtaaaggaa ttgcaccttt gccaagtgct tctagcttag aagatgttac gaataaatgg
    29281 atggaaatta aagatgcatt taaaactggt aaaacaagta ttataaacac tttagcatta
    29341 aagaatatag aagcaagttt gaataataca ctggtggaat tatctgagaa aataaaaaca
    29401 agttttgata gttcagacgc tagtgtacaa gatttgatga atcagttaac acaagctaat
    29461 aatactataa gtcagttaaa tacaagatat aaagttgcta gtggtacagt tactcctttt
    29521 aagggtgatg acactaaaat tgcttatcca tatctaactg atagagtttt taaacctagc
    29581 gcttgggtta aaattagtaa cttagatttt aagcctaata ttttctttgc tgattttgat
    29641 tactatgata ctgaatataa aaataattat aaacttttcc ttttcgcttg ttgtggtgtt
    29701 gctacacaaa gaggtgttga tttttcaagt gttacatctt ttgttagaaa aagtagtgat
    29761 gagtattttc atgctaatgg ctggctctat aataattccg aaggagatgt ttattttaat
    29821 aatactggtg ttcaaattcc agcttatagc tttgactcaa ctcaaagaca tatttataaa
    29881 tggtatgcta ttaaatttat ttaagaagga gaagaaacat gaatgttcca aatagagtaa
    29941 tatatgacca aacaggtaaa ataatttttg aaacaggtga gtcctgtggg gatgtgttac
    30001 cacacaataa aataactgaa ttacattata ttgatattcc atatggaagt atagattata
    30061 ttaaaaatag aattgtaggt ataaatatag aaacaaaaca gccaattttg gaagaaatac
    30121 cagtatatgt aagtgaagca gaaaaagaaa aacaagagtt agaaaatcaa ttacttttat
    30181 tgacaaatca agaaatcgga ggaggaattt tataatgaat ataaataatg ttgtagtaag
    30241 aatattggcg gagagaatat taaacaaagg attgaaccct ttaaaaaaca gaccttttga
    30301 gttagatgac gtaactaaca cagaatacag aaaagccgta gaggattata taattaaaga
    30361 aagtggagta gtagaaggag cagaacctac ggcgtaaggt tcttttttta tttcaattaa
    30421 ttaggaggtt ttcatgaatg aagaagttat aaaagaaaaa ataaaacgaa atgaaataag
    30481 aataaacaga cacagtgatg aaatagacga attaaagata gcaaatatag agtctaaagc
    30541 agagttaaaa gcattgtgtg agaatctaaa ttcacttaca agtatgttga agtggctgat
    30601 aggaacaatg attacaacac taatagggtt ctttatattt gctattcaga gaggaatatt
    30661 ttaaattagg aggataaaag atggataatt taataagttt tataccagag cagttactaa
    30721 ttttagtagc tgctctttat gttataggag caggttgcaa gaaatataag caattagata
    30781 acaagtatat tccagtagtg ttattgatac ttggtatagg tttctcaata tggatgctag
    30841 gattaaatcc tagtgcagtt ttacagggaa taatctgttg gggagttgca ataggtataa
    30901 atcaaactta caaacagttg aaggaggaaa ataaataatg aaaatatgta ttacagtagg
    30961 acacagtatt ttaaaaagtg gtgcatgcac ttctgctgat ggggtagtta acgaatacca
    31021 atacaataaa tttcttgcac cagtattagc agatacattt agaaaagaag gtcataaggc
    31081 agatgtaata atatgccctg aaaagcagtt taaaactaaa gcagaagaaa agatttataa
    31141 aatacctaga gttaatagtg gaggatatga tttacttata gagttacatt taaatgcaag
    31201 taacggtcaa ggaaaaggtt cagaagttct atattatagt aataaaggtt tagaatatgc
    31261 aactagaata tgtaataagc taggtacagt atttagaaat agaagagcta aattagataa
    31321 aggattatat atcttaaata gttcaaagcc tacagcagta ttaattgaaa gtttcttctg
    31381 tgataataaa gaagattatg agaaggctaa gaaacttgga tatgaaggaa tggctaagtt
    31441 aattgttgag ggtgtattga ataaaaatat aggtgatgag ggagtcaaag agatgtacaa
    31501 acatacaata gtttatagtg gagaagttga caaaatccct gcaactgtag ttggttgggg
    31561 gtataatgat gggaaaatat tgatatgtga tataaaagac tacgtaccag gtcagacaga
    31621 aaatttatat attgttggtg gtggagcatg tgaaaagata agttctataa caaaagaaca
    31681 ttatacaatg ataaaaggta atgatagatt tgatacactt tacaaagcgt tagattttat
    31741 taagaaataa gtttgtagag agtggtaact atttcatcag ttaccactct ctcttttttt
    31801 atcctttttg ttatattctc tttcaagtgc tgttttttta aaaacccatg tcgttccgaa
    31861 ttttttacag tctacacctt ccacaaattt tccgtttctt atattaagtc ttaacgtact
    31921 ttcacctttt ttataaagtt cacaagcatc ttttatagag attagttcct caaatacatc
    31981 tttcatttta acaactcctt ttacttatat tataatcgca aaagtttaaa aagacaaggg
    32041 gaaaataagc gtaaaagttt aataaaagtg ttgactcaat aaacgtaaac gtttataata
    32101 taattaaaga aagataaaca aagggggata taaaaatgga aaaattcatc agacttgatt
    32161 acgataaggg ctttagagga aaagaacatg taagttctgc aactggagat ggagaacatt
    32221 ttgaagcagg aattagttgt tataaaataa gtaaagaaaa atgtgttgat gctataataa
    32281 atttatgtga atattggttt gaatttgcag gtgaatgtca attcaaagat ttcgatataa
    32341 atatttttga aggatgctat gtaggtgagg gggctagtta cgaagattta gccacttgtg
    32401 agaaacattt atatactgta gatggttctt tattcaatga agtttatgac ttatattata
    32461 tgcatgaaac atacttagaa gaaaatggaa atgttgaaga attagaagaa aactacaaag
    32521 atgaatatat aacaacagaa gaatttgaaa ctaagataaa agaaatgttt ataaaatatc
    32581 tgtaggaagt gaaaacatga aaattggaga taaatttgaa aatcttacaa tactagatat
    32641 agaacaaaaa aatggcagga aatattgctt atgtaaatgt agtaattgca ataatgaaaa
    32701 atggataagg gcagatagtt taaaaagaat aaaagcatgt ggatgcatga aaagtaacac
    32761 acagtttaaa caaaatgatt taacaggcaa aaagtttggc agattaacag caataaagaa
    32821 cactaataaa aaagctaaaa gtggtcacta tatttgggct tgtaagtgtg attgtggaaa
    32881 tgagattaag acagcagaaa acaatttaac tactggtaga actaaatcat gtggatgctt
    32941 gaaaaaggaa tctaatataa aaaatgcaaa gatagcgtta aaagtacata aagaaaaaaa
    33001 tattattgat gatacaaatc tatctattat aaaaaagaca gaagcgtatt ctaattcaaa
    33061 aactaaaatt agaggcgttt cttggaataa agaaaaaaga aaatactgtg cacaaataga
    33121 atttaagaaa atgcattata atctaggata ctatgacaac ataagagaag cagaagaagc
    33181 atacaaaaaa gccaaagaaa aattcttaaa agaaataaac ggaaaagttt aaaaaactat
    33241 tgacttaata aacgcaaacg tttataatat aattaaagaa agaaataatc aaaaggagga
    33301 tataaaaaat gaataaacaa aaagctagaa gatttttaag agttatagat atgaatatag
    33361 ataaaataga agaagaagct ataaaagctt ttaaagaaag ttgtttaatc aaagagacta
    33421 atgatataaa aatttatatc gatatacaag gaaaagttga agcgatagca gttcaaactt
    33481 gggctaaact tttagatgat gacaaagaaa ttaatatttt cacattaaat caagcaccaa
    33541 ctcatttaga cgatatgttt ggagaaattt accatgtaaa tgattatgaa gagttcgaaa
    33601 aatggtgtga aaaaggaaga taaaagtttg aattgggata gttatgaaaa attcaataaa
    33661 gaaaatttcg aagaaatcgc tgaaagaaat atagatgata gctcatcagc ttttttagaa
    33721 aaattacgtg aaggcattga aaattgtaaa caagaattac aaaatatagt tgaaaattaa
    33781 gtagaagagt attattatta atgtatatag tatcgctttt ggttaactat aagggattta
    33841 aaatattttt taatttattt agaaatgata ttgtaataag aattttcaga ttaactatga
    33901 gggatttaaa tgtcaattta atttataga
//
LOCUS       DAMJXI010000038        31570 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.040, whole genome shotgun sequence.
ACCESSION   DAMJXI010000038 DAMJXI010000000
VERSION     DAMJXI010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31570
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.040"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            224..1303
                     /locus_tag="PC465_002357"
     CDS             224..1303
                     /locus_tag="PC465_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDF2649648.1"
                     /translation="MPELLKNMYNRESLYEVAVAIQSVYNSFKVDEFIKSTMDETWNN
                     LELKARCRKISMSLGMYLPEDYKEALSILEKSVTGFYFAFFFPDFVEVYGQDDINWDL
                     SISALERNTEYWSSEFAVRAFIIKDEDRMMAQMRKWSKHKSEHVRRLASEGCRPQLPW
                     GQAISKFKKDPTPVLPILEQLKTDTSTYVQKSVANNLNDISKTHPDLVISIAKDWYGK
                     NKSTNWIVKHGCRTLLKKGNRDVLALFGYDDTTSINLQDFTLETTSISIGEDLTFSFN
                     ILAKKATKTRLEYGIDYIKSNGKRNRKIFKISEVSLKENEKKSYMKKHSFADVSVRRH
                     YPGIHSIAIIINGIEKDKLDFELGI"
     gene            1627..1995
                     /locus_tag="PC465_002358"
     CDS             1627..1995
                     /locus_tag="PC465_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HDF2649649.1"
                     /translation="MDVYSFWNDTLAQDAVKIRKYFHEDAYINWHDTNEHFTLEEFII
                     ANCEYPDKWNGKVEKVLEFGNLVITVTHVYAINKPLSFHVVSFISLKDDKIISIDEYW
                     GEDDDVPQWRLDKHIGKPIK"
     gene            2112..2909
                     /locus_tag="PC465_002359"
     CDS             2112..2909
                     /locus_tag="PC465_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2649650.1"
                     /translation="MEEKYILSDRGKVYYWIKESNSVFAKNLIFLPGLTANHHLFDFQ
                     IQYFSKNHNVLVWDAPAHGKSRPYLDFSYSNLVEELKVILDKQNMKKVVLIGQSAGGF
                     VAQSFIVKYPNMVEGLMMIGTCPYGTDYYSKSDIFWLKQTEWMLKLFPDKLLRNIISK
                     MCGATSEGRRSMMKMLEGYEKKELCHLMYLGFAGFIPEIQDLNIHCPVCLVVGDKDKT
                     GKVRKYNEQWHNKTGYPLHIIKNASHNVNVDKPNELNQIMDIFIKQL"
     gene            3308..4198
                     /locus_tag="PC465_002360"
     CDS             3308..4198
                     /locus_tag="PC465_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2649651.1"
                     /translation="MIESIPAKQILQKVKFDNTRWFGIDYNMNLYRGCSHGCIYCDSR
                     STIYNIENFDKVRYKENVIEILSKELRSKRKKGVVGIGAMSDTYNPFEKQLCITKQAL
                     DLISENHFGVSIDTKSSLVVRDIPILQKIKKNNSAIVKLTITTANDELSKKIEPYVNP
                     SSVRFDAVKELNDSGIFCGILLTPMLPFLTDNKDEIRAIVEKAHKANAKFIYCMYGVT
                     MRSGQREFFYEHLRDISPKLVFKYQKTYGLNYVCTVQNKDCCEKLLREECARYGILTD
                     MKEIIKAYKRSESYIQIKFF"
     gene            5064..5453
                     /locus_tag="PC465_002361"
     CDS             5064..5453
                     /locus_tag="PC465_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010966715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2649652.1"
                     /translation="MLADPCEEMIDKYLNKGTMYALYDNKELTCIAVVNEISKEICEL
                     KNIATYEHFQNMGYASKMIYHLLDVYSKKYSSMVVGTSESGVPFYEKFGFVYSHKIKN
                     FFVDNYPEPIFEGELQCVDMLYLSYNF"
     gene            5625..5795
                     /locus_tag="PC465_002362"
     CDS             5625..5795
                     /locus_tag="PC465_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649653.1"
                     /translation="MDSNNNTIKSTVKKGISFDSCLAMIISYTAWKSIPWAIFHGLMS
                     WIYVLYYWVKYA"
     gene            6169..7278
                     /locus_tag="PC465_002363"
     CDS             6169..7278
                     /locus_tag="PC465_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDF2649654.1"
                     /translation="MKEKLEEKSKIIKTSKEYKRTIIEEKDREWTKKLNDILSRGDFS
                     NEKLDKIKDLIPKEILTSENVGEVVTEDGYAKPEYDEVFKSLFTLNNDYDLLANFIND
                     ILKDAPYANRNIKQFTQIKRIIKVETDPTINYIGEKRPRLDILAEDEERNHINIEMQR
                     ALEEDYLERAEYYLSRVHGRKLEEGKEYKEIGKTVGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIFSSKTALYFIELPKIRKSSCIANRVLIWGKLIDNPSHIDIRILSKTDYVIK
                     RALDRLKELGSNEDYLLNLKRGAYIMNKSRNFKEEIFQEGIEKGIEKGIAKGKREEKF
                     NIIIKLKNKGYNLSEICDIIDDLNKSEVEKVYNQN"
     gene            7483..7971
                     /locus_tag="PC465_002364"
     CDS             7483..7971
                     /locus_tag="PC465_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3841 domain-containing protein"
                     /protein_id="HDF2649655.1"
                     /translation="MKFYTIQTLEFWNNNKNNKYLSNDYSFILEDFDIPYKWMYSQMT
                     NRIYEFDDSMIWVWTKRPDLRCSGYLEKGKKGVLLEIEISEDNVLLSEFDLWHLPLMD
                     IAVELYEDEQIEKKVSWERIFDLELCSKLNEVNIEDLTLQGVTSKVPLSNVKLIKEFV
                     AK"
     gene            8057..8464
                     /locus_tag="PC465_002365"
     CDS             8057..8464
                     /locus_tag="PC465_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649656.1"
                     /translation="MSKQQTGIKSTLISEILGISYCIGATLVNKYFFKGSSIEYLPII
                     IWVLAMGAQWVYNKKYDDLIDEASKCILSRVNDIAIKVLFFSVAIVSIFLVTLDINVS
                     NLNIGMSLLVILFIQSLLKLILFIYFDRKGIYN"
     gene            8465..8683
                     /locus_tag="PC465_002366"
     CDS             8465..8683
                     /locus_tag="PC465_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2649657.1"
                     /translation="MSVLLKTKIKSYREKNLMTQGELAKSVGVRRETIVHLENGRYNP
                     SLKLAMDIAKVFDTTVEELFEFIEENNI"
     gene            9542..9847
                     /locus_tag="PC465_002367"
     CDS             9542..9847
                     /locus_tag="PC465_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649658.1"
                     /translation="MPSMIMEVVGVLFIAIGLILTFIEIKGNFPSFYGFGQNSIGKNA
                     VGIIAAGIALIFFRNGIDSIDSIATYGVFLAIELVVIVAYFLIRKKFTKEDKHLRTN"
     gene            10255..10944
                     /locus_tag="PC465_002368"
     CDS             10255..10944
                     /locus_tag="PC465_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2649659.1"
                     /translation="MDILLVEDDKNIREMVYDFLISENYSVKTAIDGNTAIEIFKNYS
                     FDIILLDLMLPKSSGFEVLKYIRSVSVVPVIITTAKDSDTDKMLGLNLGADDYITKPF
                     SIVELLARIKANIRRATVYSSSRNSQDMVIQYKDLIINISKYVVSKSGIALNLTHTEF
                     EIVKLLATNQGRAFSKEQLYNAIWKEPYYGNENVLNTHINRLRNKLSDGMEKNNYIKT
                     LWGIGYKMEEE"
     gene            10944..11861
                     /locus_tag="PC465_002369"
     CDS             10944..11861
                     /locus_tag="PC465_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2649660.1"
                     /translation="MELFLVVISIVLFALYLKERNKSKKMESDYKYINSRLRDITNDD
                     EINYILVPSDISIVKETAVDINKLLEKFYSRQINYNRSEKAILQIFTNISHDLRTPIT
                     VLKGYIEMLYLQSQKEELSSSMRATVEKMQTNSNELVNSINNLFNMAKIQSGDMILNL
                     QKSNLTQLCHEIILEFYDLLDKENFNVEVNIEDRPIYANVDTEALQRILKNLIDNAIK
                     YGSDGRFLGISLYEKEKHVFIDIEDKGSGISETEKEHIFTRAYTADRKKGNGLGLAIS
                     QGLANSMGGSIYVNSRPNVKTVFTVKLKS"
     gene            11934..12860
                     /locus_tag="PC465_002370"
     CDS             11934..12860
                     /locus_tag="PC465_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2649661.1"
                     /translation="MNYIIETHQLKKIYKDKAVVNAVNIHVKKGEIYGFVGPNGAGKS
                     TVMKMLLNLVKLNSGEIVMFGKKVAETDFEILKKIGTIIENPYFYENLTAKQNLDLHC
                     EYMGYYNKEHISEVLECVGLSKQSNKKVSKYSLGMKQRLAIARAILTKPELLILDEPI
                     NALDPEGIREMRELFRKLNTDYGITIFISSHILSEVEQIADTIGIIQDGKLIKEISMS
                     DIHKYQTDYVEVDVDNVELAGYLLEKEFGIKDFKITSESCIEIYDLRKDVKEISKIFI
                     QNQIGINSIGRKQSSLEDYFFQTTGTGGKETL"
     gene            12857..13537
                     /locus_tag="PC465_002371"
     CDS             12857..13537
                     /locus_tag="PC465_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2649662.1"
                     /translation="MIHLMKLELKKVGLKRYFLFSMLGIFLCMFFVFTGLNDKSTSIY
                     DYDVTFRTISLFFCFYYIILFAVLNVAYIINEYTNKTILILFSYPLDRKKLILSKLLL
                     ITTLMISSMIVGYICCFTFVVVLDKYFNLVIGDFHISILSYWIPGAIKSIIVFCSLGI
                     WTLVVGMIRKSIPVTLVSSIIFINLRQFILAGTNTTQDSLISVFIIVGITVIGIYYIL
                     NHKVTEID"
     gene            13982..14683
                     /locus_tag="PC465_002372"
     CDS             13982..14683
                     /locus_tag="PC465_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDF2649663.1"
                     /translation="MNNSFLDKLIETKELKNSLYNVLKHNFLYHSNKIEGSTFTTEAL
                     ALLLDKNVVTGKHTLDDVQETVNSSYVFDTIIDSLKEKITHNFLRNLHSSLIFNTTLN
                     SRGMSGIYKTIPNMILGTDVSIAQPFEVEPKLDELIEWYYSQSEVSIKVIAEFHYRFE
                     LIHPFQDGNGRIGRFVMLKQMLENNLPIKIVSWDSEDLYRNSLNSCSLGNYVPLIEYL
                     SSLEDFREVYKMLWK"
     gene            15668..16318
                     /locus_tag="PC465_002373"
     CDS             15668..16318
                     /locus_tag="PC465_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2649664.1"
                     /translation="MKVKSNLDEILYHKIIESLIRGEYSVGQKILLNDLCEKFEVSRT
                     PVVQAVKMLNKDGVLTIMTNGKVYVPEYEYDMVKQVCETRTLIETYALEKMMQEEEEV
                     FQQKLDVIKRYSDKCEEYYRQEKSVELALADLELHKAIVEGANNEILNDVYVGIQGRF
                     IVVNYLIRPLKNRNYEGTVQDHFEILKFIEDRDTKKAVDKLRNHIQGTIKRFCEDE"
     gene            16634..18694
                     /locus_tag="PC465_002374"
     CDS             16634..18694
                     /locus_tag="PC465_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HDF2649665.1"
                     /translation="MKEVVGSLKKITKERIENTMKKLFTSETFLEYQFISDCQISPNG
                     GYTAFIVKKADIKENGYTSQVYILNNKTGELKQITSINSVGAYAWEDENTILFPALRN
                     EKVKDAVKNGKQCMSYYALSLNGGEAEELFRLPIKGGKLNPIGKGLYAVVDSYDNDRP
                     IVEGLPEEEQQKKINAYNKRHYEHFKEIPYAVNGEGYISRKRKRLYVYDSNINELKAI
                     TAPMFNVVGMKISDGKILYIGQEFKDVKGLKNGVYVFDTNTNVCILEKDKYIIKGFEL
                     YQNQVILNLTDALSYGNGENGDFYTIDIDTKEMKLLSGHQHHCIGNTVTSDVKMGAGQ
                     TTKVDGEYIYYTSTVDMDCIIERIHIPTGKQEKVTQTGSVDFIDVKDGNIVCVGCLGN
                     GLPEVYTVENGTLCKKTHLNDHILEEYKISVPEYIESKGSSKWEIQGYVYKPVDYEVG
                     KKYPAVLAIHGGPRLTYGPYFMNEIQVFTSAGYFVFFCNPRGSEGRGNAFADIRKQFG
                     DIDYIDFMEFTDTVLEKYTDIDKTKLAVEGGSYGGFMTNWIIGHTNRFAVACAQRSIA
                     NWSGMEGTTDIGYYFCKGQTGASHMENHELQWKQSPLAYADKCVTPTLFLHGEKDYRC
                     YMQEAFQMFSALKIHGCPTKLCLFEGENHELSRSGRPKQKLQRLVEMLDWFSVYIKKD
                     NIGQ"
     gene            18711..20666
                     /locus_tag="PC465_002375"
     CDS             18711..20666
                     /locus_tag="PC465_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HDF2649666.1"
                     /translation="MEKIKIESSDIFEYIFPHDISCSPDGKHIAYIISNINEEKDCYE
                     HDLYVMDIKTEKQIHMTQTKDVTSFSWISNTELLFTSKRNKPKASTTDFYTISIEGGE
                     AKKAFSIPKACSVPVSLGNKLWLLTTKNPTDSKKSEPDRAVEGVDYWTFTDKPFIRDG
                     ENFSQRRRVTLELYQEGENITKAITPKFCEVAGVDVSSDKNRILYTGQIYEDCATPFS
                     GLWEYHIDSGETKELVPQGKYQISLAKYIGKDKVMLQASTLDRSITQNHDIFILDLST
                     SEINMIASPDGMYATLLDVDAVYGGGRSNKVIGDKFIGARICRTMTEFNEFDTKTGNI
                     RIITKVDAFTSFDIYDNTMYTVMLKDYELAEIYSIDMTTGTMKKMTAFSEPYLDTHKV
                     SLPEKLTFVAKNKEEVDGFVIPPIDAKEGEKYPAVLFIHGGPKWAYGYMFTHLKQCVT
                     SKGMYVIYCNPHGGDGYGEKFLEMVERWGYVDYEHLMEFVDTCIEKYPGIDADRLGVA
                     GGSYGGYMTNWIIGHTDRFKAAVSQRGISNLITASLIIDFGDRIMKQTCGDKTPWNHE
                     EVLWNHSPIKYVKNVKTPTLFLHSDRDYRCFMGDTFQMFTALKQLGVDTEMYLFHGDT
                     HGLSRNGRPSNRIARANAIVDWFERYL"
     gene            20682..21872
                     /locus_tag="PC465_002376"
     CDS             20682..21872
                     /locus_tag="PC465_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDF2649667.1"
                     /translation="MSDMLLWFSVVLVLFAIGDLIASKTKAKVSAVFVTLLLFLILFV
                     TKAIPADIIEKAGMTAAASWSVPMIMFSMGTMLNVKQFIDEWRTVLTAWLGIVAVIVC
                     VSLCIPLFGKSTVLTSIPVINGALPATTIMTQAALEKGLTLAAATATVVFAIQKFIGT
                     PIASRAALQEANRLLVEYHEAKSKGIDLANVDTDKKEAENTGTKVKQAFCEKYDKYYS
                     TNVCIFFIALFSYLGYELSEIIHVNYSIVCLVVGVIVTRIGIVPKDILEKGKIKGFIN
                     MVVFAAVIPSLAKVSLTDLISLFVPIVGMFAASIIGIFLMMKVLPGWKIIGSKPLAFG
                     VGFCQMLGFPTTYLISNEVCNAVGETEEERAYLMSKIMPKLVVGGMACMISIVVAGLM
                     VPML"
     gene            23051..23425
                     /locus_tag="PC465_002377"
     CDS             23051..23425
                     /locus_tag="PC465_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2649668.1"
                     /translation="MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFAN
                     DLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEILRDSKRRIVEQKMADMIKD
                     AKALGITQIELQEMMDILYQED"
     gene            23427..24284
                     /locus_tag="PC465_002378"
     CDS             23427..24284
                     /locus_tag="PC465_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2649669.1"
                     /translation="MENILEVYNLNKTYTDFSLSNISFALPEDCITGFIGVNGAGKTT
                     TIRSILDVVKRDSGKIKIFGKDFDGNEKELKNRIGVVFDDSYFYEELSMAEMKSIIAP
                     SYDNWCEEDYQQNMKRFNLNPKQKIDTLSKGMKMKFALALALSHKAEFLIMDEPTSGL
                     DPLIRSQILDILTGYMKKCGRGVFFSTHITSDLDKIADMIVMIDNGRIILEREKDTLL
                     DEHRKVKGDIQFLNDETKKLFLNLEITGYGFIGITSKINEVQKNMPDILIERPTIEDI
                     MLAYIERRE"
     gene            24287..24925
                     /locus_tag="PC465_002379"
     CDS             24287..24925
                     /locus_tag="PC465_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HDF2649670.1"
                     /translation="MLIHLVKKDILIVKKYVLLILFIAIGIPLFILWRLPPFAQILGF
                     VLSIIFSEFMLCQYLLLKESQYSKASVLLCSTPYPRRGLVQSKYVLFAMVFIYCTLVY
                     WIENLLIPQIGTFDLTYILIVLLISSIIYGVYMPIQYKLGYETTKFFFVVIIMASSFV
                     LPLTIAHSNFEIPFIYQYPSMIVNIVLFLLSLIILLASMFISIKIFSNKELV"
     gene            25931..26665
                     /locus_tag="PC465_002380"
     CDS             25931..26665
                     /locus_tag="PC465_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2649671.1"
                     /translation="MNLAKGLDVLKISSNVFGEDKVMYIPVIYTEDDATLIDTGLPGQ
                     GDLIIDALNKSNTSFDRLKNIIITHHDIDHIGNINYLREKSKNNIKVYAYKSEVSYIT
                     GEETPFKLYMLEQMVDKIDDKMLSMLNVMGLGFKSSYTKVDVSLDNHEKLNLGEEIEV
                     IHTGGHTRGHICLYLKESKVLIAGDLLQVENGELKPVDVMYSNKQELKDAIKNISNYN
                     IETIVFSHGGLYQRNIIGTLKNLIIE"
     gene            28004..29260
                     /locus_tag="PC465_002381"
     CDS             28004..29260
                     /locus_tag="PC465_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HDF2649672.1"
                     /translation="MIEKFKTLIWIKMIIRIKSVYKTYGGLFFLGLIGIPVGAIIGLI
                     DTIFGTVLLKVTDIRETYPMYLIPFLAVVGVVIAYCYFKFGGKSSKGMNLIFEVGHGE
                     EEIIPLRLVPFIISGTWLTHLFGGSAGREGVAVQIGATFSHWVGKRLPIKNASSIFLV
                     TGMAAGFAGLFETPIAAILFAMEVLVAGSLEYQSLFPAFTASFTASAVSKALGLEKFS
                     FALSSEVVFDLSIFWKLIVLGIIFGMVGGAFAWCLKLSKRKIGNRLKNPMIRIAIIGV
                     CLSVLFLLFYKGRYSGLGTNLIQNSFYGGEIYSFDWLLKFILTILTLSAGFQGGEVTP
                     LFSIGASLGVLLAGFFNLPIELVAALGYASVFGSATNTFFAPVFIGAEVFGYSYLPYF
                     FVVCAISYIFNMDKSIYSLQKISTKQ"
     gene            29323..30516
                     /locus_tag="PC465_002382"
     CDS             29323..30516
                     /locus_tag="PC465_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDF2649673.1"
                     /translation="MLTSLALIFLLGMASGGIFKRIKLPNLLGMLLTGIILGPYVLNL
                     IDNSILDISSDLRKIALIIILTRAGLSLDINDLKKVGRPAVLMCFIPATFEIIGMIVL
                     APKLLGVSILEAAVMGAVVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDI
                     FVIVMFTVFTGLAQGNSISAISFLQIPVSIILGVIAGAVIGICLAVFFKKVHMRDSAK
                     GVLLLSISFLMISLETALEGIVPFSGLLAVMSIGIFLQIKYRVVARRLSIKYSKLWVG
                     AEILLFVLVGATVDISYAFKAGIGAVILIFGVLLFRMVGVFFCLIKTNLTIKERLFCM
                     IGYIPKATVQAAIGGVPLAMGMASGQLILTLAVLAILITAPLGAFGIDVTYKKLLTSV
                     KGESK"
     gene            30717..31097
                     /locus_tag="PC465_002383"
     CDS             30717..31097
                     /locus_tag="PC465_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2649674.1"
                     /translation="MCLKKLSKLELVIMKFIWNLDIKTNSYEIIDYMKEEHNLPEKVA
                     LKTLSKLSKKRFLYVQETGKCMYYTVAIKEKAYLEFISRNVQNLLKNNFIRNLLVSFH
                     EEELTEEKIKSLENWVVNWEEAYV"
BASE COUNT        12086 a         3316 c         5376 g        10792 t
ORIGIN      
        1 cagtaaagta taaaattcta ttactataat aaaagataga actagaagtc tttatgaaag
       61 tgggaaaagt atttatataa ataaatttat atagtttaac agtaggaaat atcgtatgag
      121 taagactatc gtattttaca taaagattta gcaatatgac acactgttgt cgtgttctgt
      181 agggtatgat taataaatca gatatgaaag gagagtgagt aatatgccag aattactaaa
      241 aaatatgtat aatcgtgagt cactttatga agttgcagta gctatccaat cagtttataa
      301 ctcatttaag gtagacgagt tcataaaatc tacaatggat gagacatgga ataacttaga
      361 attaaaagcc agatgtcgaa agataagtat gagtttagga atgtatttac cagaagacta
      421 taaggaagct ctttccattc ttgaaaaatc agttacaggt ttttattttg cttttttctt
      481 tccagatttt gttgaagttt atgggcagga cgacataaat tgggatttat ctataagtgc
      541 attagaaaga aatactgagt attggtcttc agaatttgct gtaagagcat ttatcatcaa
      601 ggatgaagat cgtatgatgg cacagatgcg taaatggtct aagcataaga gcgaacatgt
      661 acgaagactt gcaagtgaag gttgtcgtcc ccagttgcct tggggacaag caatatccaa
      721 atttaaaaaa gaccctacac ctgtactgcc tatattggag caacttaaaa cagatacatc
      781 aacgtatgta caaaagagtg ttgctaataa tctaaatgat atctcaaaaa cacatccaga
      841 tttagtcata agcattgcaa aggattggta cggtaaaaat aaatccacta actggattgt
      901 aaagcatggt tgcagaactc tgctaaaaaa aggcaatcgt gatgtattag ccctttttgg
      961 atatgatgat actacttcta taaatcttca ggactttact ttagaaacaa cgtctatttc
     1021 tattggagag gatttaactt tttcatttaa tattttagca aaaaaagcga caaaaacaag
     1081 gctcgagtac ggaattgatt atattaaatc taatggaaaa aggaatagga agatatttaa
     1141 aatatcggag gtttcattaa aagaaaatga gaaaaagtca tatatgaaaa aacattcatt
     1201 tgcagatgta agtgtaagga gacattatcc aggcatccac tcgattgcta ttattattaa
     1261 tggtatagaa aaagataaac ttgattttga attaggtata taattttact aacagaataa
     1321 tctatatcag atactttgct aaacttatat aatatatttt actaaattta tattaggtag
     1381 tttactactt gtttactgaa tttaaataca aagaaataca ggtgttaatc cctgcccatt
     1441 aaaggaatat gagcataaca caaaagtaga acttatcaat tctgttacaa gtacagtagt
     1501 aaatcctcat aatcacaatt agcaaatgaa gtgtaaaaaa taagttagtg ttgattttag
     1561 ttgctagtga tattgaatag ttatacaata gccatataaa ttagaatttg tagaggagaa
     1621 atgtaaatgg atgtatatag tttttggaat gacactttgg cacaagatgc tgttaagata
     1681 agaaaatatt ttcatgaaga tgcttatatt aattggcatg atacaaatga gcattttact
     1741 ttagaagaat ttattattgc aaattgtgag tatcctgata aatggaatgg taaagtagaa
     1801 aaggtgctag aatttggaaa tttagtaatt acagtgacac atgtttatgc aataaataaa
     1861 ccactatcat ttcatgtcgt ttcatttatc agccttaaag atgataagat tatttctatt
     1921 gatgaatatt ggggagagga tgatgatgtg ccacagtgga gattagataa acatattgga
     1981 aagccaataa aatagtgttt gttctgtttt ataactgaaa ttttgataac atttgatact
     2041 ttgatttgtc attggtcaac atagtcgtta gtgtaataat ttaaaaaagt agaatttgga
     2101 gagtgagcac tatggaagaa aaatacatct tatctgaccg aggtaaagta tattattgga
     2161 taaaagaaag taatagtgtg tttgcaaaga acttaatttt tttgccagga ctaacagcaa
     2221 atcatcatct ttttgatttc caaatacagt acttttcaaa aaatcataat gtattggtat
     2281 gggacgctcc tgctcatgga aaatcaagac cttacttaga tttctcatat tctaacttgg
     2341 tagaagaatt gaaagtaatt ttagataaac aaaatatgaa aaaggttgta cttatagggc
     2401 aatcggcagg gggatttgtg gcacagtcct ttattgtaaa atatccaaat atggtagaag
     2461 gattaatgat gattggaact tgtccatatg gaactgacta ttatagtaag tcagatattt
     2521 tctggttaaa acagactgaa tggatgttaa agttattccc agataaattg ttgagaaaca
     2581 taatatctaa gatgtgtgga gctacgtctg aaggcagaag gagtatgatg aaaatgttag
     2641 aaggctacga aaaaaaagaa ctgtgtcatc tcatgtatct gggatttgct gggttcatac
     2701 cagaaattca agacttaaat atacattgtc cagtttgttt ggtggttgga gataaagaca
     2761 agacgggtaa agtgagaaaa tataatgagc agtggcacaa taagactggg tatccattgc
     2821 acattataaa aaatgcttca cataatgtaa atgtcgataa acctaatgaa ctaaatcaga
     2881 ttatggatat atttattaag caattataat atataaaaat tacataccca ttaggtaaat
     2941 tatgtagtat atgtgtttac agatggttat agaaataaat atgtaataaa ctacttaaca
     3001 cttaaaaagt ggatttgtcc agagcataat acaaagcatg atatatataa atttttaagc
     3061 gaaatacatc aaaagaagga ttagaattag tggagacaga acagctatta tagattataa
     3121 ataaatagtt ttaaaggatg ggtactacga atatagagga aggtaaatca tacgttattc
     3181 aaggattata aatgattagt ttaaaagtac tatcggatag gagtctccat atttaaacct
     3241 tagtaaaggt agttaaagta gtagtttaaa aactaaaaaa ttatataaag gaattaggta
     3301 taagaaaatg attgagagta taccagcaaa acaaatttta caaaaagtga aatttgacaa
     3361 tacaagatgg tttggaattg actataatat gaatctctat cgtggctgtt ctcatggatg
     3421 tatatattgt gatagccgta gcacaatata caacatagag aattttgaca aagttagata
     3481 taaagaaaat gtgatagaaa ttttaagtaa agaattgcgt tcaaaaagaa aaaaaggggt
     3541 agtaggcatt ggagctatgt ctgacacata taatcctttt gaaaagcaac tttgtattac
     3601 aaagcaagca ctagatttga tttcggaaaa tcattttgga gtatctattg atactaaaag
     3661 tagtttggtg gttagagata taccgatttt gcagaaaatt aaaaaaaata attctgctat
     3721 tgtaaagttg actataacca ctgcaaatga tgaattatca aagaaaatag aaccttatgt
     3781 aaatccaagt tctgtacgat ttgacgcagt gaaagaactt aatgattctg gaattttttg
     3841 tggcatatta ttgactccta tgcttccatt tttgactgat aataaagatg aaatacgagc
     3901 aattgtagaa aaagcacaca aggctaatgc aaaatttatt tattgcatgt atggcgtaac
     3961 aatgcgtagt ggtcagagag agttttttta tgagcattta agagatatat caccaaaatt
     4021 ggtatttaaa tatcagaaaa catatggttt aaactatgta tgtactgtac aaaataaaga
     4081 ttgttgtgag aagttgttaa gagaagaatg tgcacgttat ggtattttga cggatatgaa
     4141 agagattata aaagcgtaca agaggtcgga gtcatatatt caaataaaat ttttttaaga
     4201 taggctttgg atgagatata atagtggtga ttgatgtgtt gatattatag ttgattgtta
     4261 gagaggatat tatagatgaa tattagtatt gatattctag gtaattgcta gagctgatat
     4321 tatagatgaa tattaatatt gatattctag gtaattgcta gagttagtat tatagatgaa
     4381 tattagtatt gatattttag gtaactgcta gagctaatat tatagatgaa tattagtatt
     4441 gatattctag gtaattgcta gagctaatat tatagataaa tattagtatt gatattctag
     4501 gtaattgcta gagctaatat tatagataaa tattagtatt gatattctag gtaattgcta
     4561 gagctgatat tatagatgaa tattagtatt gatattctag gtaactgcta gagttagtat
     4621 tatagatgaa tattaatatt gatattctag gtaattgcta gagctgatat tatagatgaa
     4681 tattaatatt gatattctag gtaattgcta gagttagtat tatagatgaa tattagtatt
     4741 gatattttag gtaattgcta gagctgatat tatagatgaa tattaatatt gatattctag
     4801 gtaattgcta gagttagtat tatagatgaa tattagtatt gatattctag gtaattgcta
     4861 gagctgatat tataatttat tattagtatt aatattctag ggaattatca ctatatttta
     4921 aaaagtaaaa atatatatca aaatgaacta aataagtact gtaagaagtt tgctaaatta
     4981 aggtttgaat aaagtgaggg tggagaactt atgatagaaa taaaaactat agaaataaat
     5041 aaaaaagtca aattgacctt ttaatgttag ccgacccatg tgaagaaatg attgataaat
     5101 atctcaataa aggaactatg tacgcattgt atgataataa agaacttact tgtatagcag
     5161 ttgtaaatga aatttccaaa gaaatatgtg aattaaaaaa cattgctaca tatgagcatt
     5221 ttcaaaatat gggttatgcc tcaaagatga tttatcatct tttagatgtt tatagtaaaa
     5281 aatattcatc aatggttgtt ggtacatctg aaagcggagt tcctttttat gagaagtttg
     5341 gatttgttta ttcacataaa attaaaaact tttttgtaga taattatcca gaaccaatct
     5401 ttgaaggaga attacaatgt gttgacatgt tgtatctatc atataacttt tagataggat
     5461 aatattttta ggttaatata cataatttat tcatataatt atcggaatta taatttataa
     5521 attatgtata ataagagtat aatttattta gaagctgtta tattgtatta gattcaaata
     5581 agatatataa taacttgttt attttgaatt ttggaggatt aattatggat tcaaataata
     5641 atactataaa atcaactgtt aaaaagggta tttcttttga ttcttgttta gcaatgatta
     5701 tttcttatac tgcatggaaa tctattccat gggctatttt tcatggctta atgagttgga
     5761 tatatgtact ttattattgg gttaagtatg catagattaa attaataaat aagtatgtaa
     5821 tattgtgaag tttaagaaac aaaacgtaag tgagtgtctc gaagtgaact ttttagttta
     5881 taaggcactc ttttttgtat taaataaaat atattttcat tacttaaaca atgaaaaaga
     5941 tgagtatctc tattttaata catactctta tattcattca tttatcaaca agagttttaa
     6001 aaagaaagct atctaaaatc tattgtaatc taagtgcttc tctttaaagt cttaacttta
     6061 gtaatgatat ataagtttat aaggttctta tttcaataat gcaaatttta cttagaagtt
     6121 cagactttgg gatgaagaaa tgggtaataa taaaaaagag gtgttgatat gaaagaaaaa
     6181 ttagaagaaa aatctaagat tattaaaaca tcaaaagagt ataaacgaac tataattgaa
     6241 gaaaaggaca gagaatggac caaaaaatta aatgacatac ttagtagagg tgatttttct
     6301 aatgaaaaat tagataaaat caaggattta attccaaaag aaatattgac tagtgaaaat
     6361 gttggagaag ttgtaactga agatgggtat gctaagcctg agtatgatga ggtatttaaa
     6421 tcattgttta ctttaaataa tgattacgat ttacttgcaa attttataaa tgatatcctc
     6481 aaagatgctc catatgctaa taggaatatc aaacagttca ctcaaataaa aagaataatt
     6541 aaggttgaaa ccgacccaac aattaattac attggtgaga aaagacctag acttgatatt
     6601 ttggctgaag atgaagaacg taaccatata aatattgaga tgcaaagagc tcttgaagag
     6661 gattatttgg aaagagctga atattatctt agtcgtgtac atggtagaaa gttagaagaa
     6721 ggtaaagaat ataaagaaat tggaaaaact gttggaatac atatactaaa tcatgtaaaa
     6781 tataatcaca tagaagatta tgtaaattgc ctgagattaa caatggacgg gcatccagat
     6841 attttttcta gtaaaactgc attatatttt atagaacttc caaaaattcg taaatccagt
     6901 tgtatagcaa acagagttct aatatggggt aaacttattg ataatccttc tcatatagat
     6961 attagaatac tatctaaaac ggattatgtt attaaaagag cacttgatag attaaaagaa
     7021 ttaggtagta atgaggacta tttattaaat ttaaagagag gtgcgtatat tatgaataaa
     7081 agtagaaatt ttaaagaaga aatttttcaa gaaggtattg aaaaaggtat cgaaaaaggt
     7141 attgcaaaag ggaaaagaga agagaaattt aatatcatca taaaattaaa aaataaagga
     7201 tacaatttga gtgaaatatg cgatattata gatgatttga ataaatcaga ggttgaaaaa
     7261 gtctataatc aaaactaata ctatgattga gatggcacta gataaataca aagcttcctc
     7321 ttttaaattt aaattaatat aaaactttgt tatttaaata tggtagatat aaagagatat
     7381 ataaataata ggtacaaaga ggtgtataaa taaaggagat aattcaaaat aaaagtttga
     7441 accatctcct tcttatagaa aaacaaaggg gttgatttat atatgaaatt ttatactata
     7501 cagactttag aattttggaa taacaataaa aacaataaat atctatcaaa tgattattct
     7561 tttatattag aagactttga tattccatac aaatggatgt atagtcaaat gacaaataga
     7621 atatatgaat ttgatgatag tatgatatgg gtttggacga agagacctga tttaagatgt
     7681 agtggttatt tagaaaaagg aaaaaaaggt gttttacttg aaatagaaat aagtgaagac
     7741 aatgtgttat tatcagaatt tgatttatgg catttacctt taatggatat tgctgtagag
     7801 ctttatgaag atgaacaaat tgaaaagaag gtaagttggg aaagaatatt tgacttagaa
     7861 ctgtgttcaa aattaaatga agttaatata gaagatttga cattgcaagg agtgacatct
     7921 aaagtgcctc tatctaatgt aaaattaata aaagaatttg ttgcaaaata atatttttat
     7981 tgaaatttat tcaaaaaagt tatatattta taacaagagg tgttataaat acataacttt
     8041 ttaaggggga ttttatatgt ctaaacaaca aactggtatt aaatcaacac ttatttcaga
     8101 aatattggga atttcttatt gtattggagc tacattagta aataagtatt tttttaaagg
     8161 aagtagtatt gaatatcttc ctataattat ttgggtatta gctatgggag ctcagtgggt
     8221 ctataataaa aagtatgatg atttaattga tgaggcatca aaatgtatac tatcaagagt
     8281 taatgatatt gcaataaaag tattgttttt ttctgtagct atagtatcta tatttcttgt
     8341 aactttggac ataaatgtgt caaatttaaa tataggaatg tctttattag tcattttgtt
     8401 tattcaatcc ttgttgaagt taattctatt tatatatttt gacagaaagg ggatatacaa
     8461 ttaggtgtca gtattactaa agacaaaaat taaatcctat agagaaaaga accttatgac
     8521 acaaggtgaa cttgcaaagt cagtaggagt aagacgtgaa actattgtac atttagaaaa
     8581 tggtcgctac aatccttctt taaaactggc aatggatatt gctaaggtat ttgatacaac
     8641 tgtagaagag ttgtttgaat ttattgaaga aaataatatt taaatttcat gtattactta
     8701 tgcattagag aatgaattaa ttataggtaa aaaaccaagc taatagatta gagaataaat
     8761 gacttataga tgaaaaacca agctaatgga ttaaagaatg aatgatttat agatgaaaaa
     8821 gaaagctaat agattagaga ataaatgact tataaataaa aaccaagcta atagattaga
     8881 gaatgaatta attataggta aaaaccaagc taatagatta gagaataaat gacttataaa
     8941 taaaaaccaa gctaatagat tagagaatga attaattata ggtaaaaatc aagctcatag
     9001 attaaaaaat aaatgattta tagatgaaga actaaactta tagattaaaa aataaatgac
     9061 ttatttatag atgaaaaacc aaacttatag attaaaaaat aaatgattta tagatgaaaa
     9121 accaaactta tagattaaaa aataaatgat ttatagatga agaactaaac ttatagatta
     9181 aaaaataaat gacttataga tgaaaaatca agctcataga ttaaagaata aataacttat
     9241 tagatgaaaa aacaagctta tagataagaa gtccatgctt ataagccaga aaatgaatac
     9301 tttaatagat taaaaaatac atatttgtga attatagaat gaatgactcc ataaactaga
     9361 aaatttataa taatatctat atgaaaatta gaattatttt atcacaaaaa aattaagtta
     9421 aataaatatg aaattacttc caaatatact tccaaaaaca tgtaatcgca tatataatat
     9481 aattataaaa ataataaata tttttatagt agtagttaat tattaataag gaggggtcaa
     9541 aatgcctagc atgattatgg aagttgtagg agtactattt atagctattg gattaatctt
     9601 gacattcatt gaaataaaag gaaatttccc ttctttttat ggttttggtc aaaattctat
     9661 agggaaaaat gctgtaggta ttatagcagc aggaattgct ttaattttct ttagaaatgg
     9721 catagatagc atagattcta tagctactta tggtgtattt ttagcaatag aacttgttgt
     9781 aatagttgca tatttcttaa taagaaaaaa atttactaaa gaagataaac atttaagaac
     9841 taattaacta aattatctac tataaaattg gaaaattaaa aacaaataaa agtttgtttt
     9901 taattattta aaatccaaat ttgattattt ttaaagaaac tatgttctgt ataaaactag
     9961 aatgtggttt cttttttatg tataaaatat tttttagcaa aagttaaaag gtgttttata
    10021 atataaaata gttaattgta gatgttaata aaagaaaatt atgtatattt cagataaaga
    10081 taagagagta tactatattt taattctttt ttcaataaag cttattgaaa agaactttaa
    10141 cttagaagag tatcaccaaa ttgcagatac aatatcataa gcagttattt attgacaacc
    10201 ctttttaata aatatatcat ttgaagtata ctgacgaaaa ggagttgaat aataatggac
    10261 atcttattgg ttgaagatga taagaatatt cgagaaatgg tatacgattt tctgattagt
    10321 gagaattact ctgttaaaac tgccattgat ggaaatacag ctattgaaat atttaaaaat
    10381 tattcatttg atattatttt actggacttg atgttaccaa agtctagtgg ttttgaagta
    10441 ttaaaatata tacgaagtgt gagtgttgtt cctgttatta ttactactgc gaaagatagt
    10501 gacacagata aaatgctagg gcttaatctt ggtgcagatg attatattac aaagcctttt
    10561 tcaatcgtag aattgcttgc aagaattaaa gctaatatta gacgtgcaac agtgtacagc
    10621 agttcaagaa actctcaaga tatggttatt cagtataaag atttgattat aaacatatca
    10681 aaatatgtag tttcaaagag tggaattgcc ttgaacttaa cacatacaga atttgaaatt
    10741 gttaaattac tagcgactaa tcaaggacgt gctttttcaa aggaacaatt atacaacgct
    10801 atttggaaag aaccttatta tggaaatgaa aatgtgctaa atactcatat taacaggtta
    10861 agaaataaat tgtctgatgg tatggaaaaa aataattata ttaaaactct ttggggaatt
    10921 ggctacaaaa tggaggaaga ataatggagt tatttttagt tgtaatttct attgtactat
    10981 ttgctctcta cttaaaagaa cgaaataaat caaagaaaat ggaaagtgat tataagtata
    11041 tcaattcaag acttcgtgac ataacaaatg atgatgaaat taattatatt ttagtaccat
    11101 ctgatatttc gattgtaaaa gaaacggcag tagatataaa taaacttctt gaaaagtttt
    11161 acagtaggca aattaattat aatagaagtg aaaaagcgat attgcaaata tttacaaaca
    11221 tatcacacga tttacgaact cccatcacag tattaaaggg ttatattgaa atgctatatc
    11281 ttcaaagtca aaaagaagaa ttatcttctt caatgagagc aactgtggaa aaaatgcaaa
    11341 caaattcaaa tgagcttgtt aattcaataa ataacctgtt taatatggca aaaatccaat
    11401 ctggagatat gatattaaat cttcaaaaat ccaatctaac acaattatgt catgagatta
    11461 ttttagagtt ttatgatttg ctagataaag aaaactttaa tgttgaagtt aatattgaag
    11521 atagacctat atatgcaaat gttgacacag aagcattaca acgtatactc aaaaatttaa
    11581 ttgataatgc tataaaatat ggttcagatg gtagattttt agggatttca ctatatgaaa
    11641 aggaaaaaca tgtttttata gatattgagg ataaaggttc aggtatttct gaaactgaaa
    11701 aagagcatat tttcacaaga gcttatactg ctgacagaaa aaaaggcaat ggtttaggtt
    11761 tggctatttc tcaagggctt gcaaactcta tgggaggttc aatttatgta aatagtagac
    11821 ctaatgtaaa aacagttttt acagtaaaat tgaaaagtta gaaaaaagtt agatttaaaa
    11881 gagagaaaag ataattttat tttgtatact gtttttagaa aggagggagt atgatgaact
    11941 atatcataga gacccatcaa ttaaagaaaa tatataaaga taaagctgtt gttaatgctg
    12001 ttaatattca tgtgaaaaaa ggagaaattt atggatttgt tggaccaaac ggggcaggta
    12061 aaagtacagt aatgaaaatg ttgctaaatc ttgttaagct aaattctgga gaaatagtta
    12121 tgttcggtaa gaaagtggca gaaactgatt ttgaaatatt aaaaaagatt ggtactatta
    12181 ttgaaaatcc ttatttctat gagaatttga ctgctaaaca gaatcttgat ttacactgtg
    12241 aatatatggg ttattataac aaagaacata tatcagaggt attggaatgt gtcggattgt
    12301 caaagcaatc aaacaagaaa gtttcaaaat attctttagg gatgaaacaa cgtcttgcaa
    12361 tagctagagc aattcttact aaaccagaat tattgattct tgatgaacct ataaatgcac
    12421 tcgacccaga ggggataaga gaaatgcgag aattattccg taagttaaat acagattatg
    12481 gaataactat atttatttct agtcatattc tttcagaggt agaacaaatt gcggacacta
    12541 ttggaattat tcaagatggt aaacttatta aagaaatttc tatgtcagat atacacaaat
    12601 atcaaacaga ttatgttgaa gtagatgtag ataatgtgga acttgctgga tacttgttag
    12661 aaaaagaatt tggaataaaa gactttaaaa ttacttcgga aagttgtatt gaaatatatg
    12721 atttacgaaa agatgtaaaa gaaatatcca aaatatttat tcaaaatcaa attggtataa
    12781 atagcattgg acgtaaacaa agttctttag aagattactt cttccaaact acaggtacag
    12841 gaggtaaaga aacactatga tacatttaat gaaactagag ctaaaaaaag ttgggctaaa
    12901 aagatatttt ttattttcaa tgctggggat tttcttatgt atgttttttg tctttactgg
    12961 attgaatgat aaatctactt caatatatga ttatgatgtt acatttagga caatcagttt
    13021 atttttctgt ttttactata ttatattatt tgctgtgttg aatgtggcat atataataaa
    13081 tgaatataca aataaaacaa tcttgatttt attctcttat ccacttgacc gtaaaaaact
    13141 tattttatca aagttacttt tgattacgac tcttatgata tcatcaatga tagttggata
    13201 tatctgttgt tttacattcg ttgttgtgtt ggataagtat tttaatttag ttattggaga
    13261 ttttcatatt tcaattttat cttattggat accaggagca attaaaagta ttattgtatt
    13321 ttgctcatta ggtatatgga cattagttgt tggaatgata agaaaatcaa tacctgttac
    13381 ccttgtcagt tcaattattt ttatcaattt aagacaattt attttagctg gtacaaatac
    13441 aactcaagac agtttgattt ctgtttttat tatagttggt ataactgtga ttggtatata
    13501 ttatatacta aatcataaag ttactgaaat tgactagata ctgtggctag gaaggtagtt
    13561 attaattgta tcttcttggg ataataatga tttgctatta tatcagctat tattaatatt
    13621 attagagttt taataatatt aataatagct atatattttt tcttcttatt tataaattta
    13681 atgatttata gtcataaaat gaactctaag aagagataaa aatacgtttt atatgttttt
    13741 agattaatat aaaatatcac aatgaaatgt tgtacaaagt gatatataat aattatatga
    13801 actataaaat tgactaaact tattgactaa taaattagat gaaaagttga gacttactga
    13861 aaataaatac aatgaaatat atactacaag tattaaatta aatctgaact ttacatacta
    13921 ttagaataag tattataaga ttataatgat ttaaaaatat taaaataatt gagatgataa
    13981 catgaacaat tcctttttag ataaattgat tgagacaaaa gaacttaaaa attcacttta
    14041 taatgtgtta aaacacaatt ttctttatca ttctaataag atagagggca gtacttttac
    14101 tactgaagca ttagcacttt tactcgataa gaatgttgtt acaggaaaac atactttaga
    14161 tgatgtacaa gaaactgtta attctagtta tgtatttgat acaataattg actcactgaa
    14221 agagaaaata acacataatt tcttaaggaa tctacattca agtttaatct tcaatacaac
    14281 cctaaattcc agggggatgt ctggtatata taaaactata cccaatatga tactaggaac
    14341 tgatgtaagc atagcacaac catttgaagt tgagccaaag cttgatgaat taattgaatg
    14401 gtactatagt cagagtgaag tatctattaa agttatagct gaatttcatt atagatttga
    14461 attgatacat ccatttcaag atggtaatgg gcgcataggt agatttgtta tgctaaaaca
    14521 gatgttagaa aataatcttc ctataaaaat tgtatcttgg gatagtgagg acttgtatag
    14581 aaactcctta aattcttgta gtttaggtaa ttatgtccct ttaatcgaat atttatcaag
    14641 tttagaagat tttagagaag tatataaaat gttatggaaa taattgtttg cagcaaaaaa
    14701 aagtttttat ataaatatat ttttatctat gctatttaac gctgatttct tagttattct
    14761 tagcttggac tatatccact attttaacta tataaaatag tggatatagt ttaactatct
    14821 ctttataact attcttatgt atcttagttg tttcttaata tggggacagt tcataaaact
    14881 aaaagtgatt tttaatttta tcatttataa tttaccatta catcagaaaa atacttatca
    14941 ttagaatttt cataaaaggt acctattttt ttcaattaac taaatcaatt ctattagtct
    15001 taatctttca tatttcaaat tgataatata agaaaataaa aaataaaaaa ttttaaattt
    15061 tttatttatt gcgaaaaaaa taaaaaggtg ctatactttt tgtaacatat tattcaaatt
    15121 attaagagat agtaaacatt tatagtttaa tttgtagtac actagcatga tttgcagaac
    15181 aatgaattaa tctatagtat aatagtttaa tttaaagtac aacgatttaa tctatagtac
    15241 aataacttga tttgaagtac aacgatttaa tctatagtac aataacttga tttgcaatac
    15301 aatgaattaa tctatggtat aatagtttaa tttgaagtac aatgaattaa tctatagtat
    15361 aatagtttaa tttgaagtac aacgatttaa tctatagtat aatagtttaa tttgaagtac
    15421 aatggtttaa tctatagtat aatagtttaa tttgaagtac aacgatttaa tctatagtac
    15481 aataacttga tttgcaatac aatgaattaa tctatagtat aagagcatga tttacagtac
    15541 aataatttaa attgtagtac aaaagtacta tcaaataaga atttctactt taaaaatatt
    15601 actaaaagta attaaagtcc agtaattcaa tataatatgg caaaagaata gaaataaggt
    15661 gagagtagtg aaagtaaagt caaatttaga tgaaatttta tatcataaga ttattgaaag
    15721 tcttattcgt ggtgaatact ctgtaggtca aaaaatatta ctaaatgacc tttgtgaaaa
    15781 atttgaagta agcagaacac cagttgtaca agcagtaaaa atgctaaata aagatggagt
    15841 gcttactatt atgacaaatg gtaaagtgta cgtaccagag tatgaatatg atatggtaaa
    15901 acaagtttgt gaaacgagaa cactgattga aacatatgct ttagaaaaaa tgatgcaaga
    15961 agaggaagag gtttttcaac aaaagctaga tgtaataaaa agatactctg ataaatgcga
    16021 ggagtactat cgtcaagaaa aatctgtaga acttgcacta gcagatttgg aattacataa
    16081 agccattgta gaaggggcaa ataatgagat tttaaatgat gtatatgttg gtatacaagg
    16141 aagatttata gtagtgaact atttaattcg accattaaaa aatcgtaatt atgaaggaac
    16201 agtacaagac cattttgaaa tattaaaatt cattgaagac agagatacaa aaaaagcagt
    16261 agataaacta agaaatcata ttcaaggaac tattaaaaga ttctgtgaag atgaataata
    16321 agttttgaag ttactatata tacttatcta ttaagttgct aaatgtagtc taagtataat
    16381 ctaattatag tttaaacata atctaaatat aatctaataa atataatcta aatatagtgt
    16441 aaataagtct aagtatgaat taaatataga ttaagtatgg actaagtata gattaagtat
    16501 gaattaagca tggattaaat atactttaaa ttacaaatat tacaaggaag ccagaaggct
    16561 tcctaaaaaa ataaccttta taaaattttt tattttaaat ttaaaatttt ttattttaaa
    16621 tttaaaataa aaaatgaaag aggtggtagg gagtttgaaa aaaattacta aagaaaggat
    16681 agaaaatact atgaaaaagc tatttacgag tgaaacattt ttggaatatc aatttataag
    16741 tgattgccaa atatcaccaa atggaggata tacagcattt attgtaaaaa aagctgatat
    16801 caaagagaat ggttacacaa gccaagttta tatattaaac aataaaactg gcgaattaaa
    16861 acaaataacg tctataaact ctgttggagc atatgcctgg gaagatgaaa atactatctt
    16921 gttccctgct ttgcgaaatg aaaaagtaaa agatgctgtc aaaaacggta agcaatgcat
    16981 gagttactat gctttatctt taaatggtgg agaagcagaa gaacttttta gactccctat
    17041 caaaggtggt aaattgaatc ctataggaaa aggtttgtat gcagttgttg attcttatga
    17101 caatgaccga cctattgtag agggattgcc agaagaagaa caacagaaaa aaataaatgc
    17161 ttataacaaa agacattatg aacatttcaa agaaattcct tatgctgtca atggggaggg
    17221 atatattagc agaaaaagaa aacgcctata tgtatacgac agtaatataa atgagttgaa
    17281 ggcaattaca gcacctatgt ttaatgttgt aggtatgaaa ataagtgatg gaaaaatctt
    17341 atatataggg caagagttta aagatgtaaa aggtttgaaa aatggggtct atgtatttga
    17401 tacaaacaca aatgtctgta tattagaaaa agataagtat attataaaag gttttgaatt
    17461 atatcaaaat caagtgatac taaacctaac tgatgcttta tcttatggaa atggagaaaa
    17521 tggagatttt tatactattg atattgatac gaaagaaatg aaacttcttt cagggcatca
    17581 acatcattgt attggaaata cagtaacatc tgatgttaaa atgggtgctg gtcagacaac
    17641 aaaggtagat ggagaatata tttattacac ttctacagta gatatggact gcattattga
    17701 aagaatacat attccaacag gaaaacagga aaaagtaaca cagacaggtt cagttgattt
    17761 tatagatgta aaagatggca atattgtatg tgtgggttgt ttaggaaatg gattaccaga
    17821 agtttataca gtagagaatg gaacattgtg taagaaaaca catttaaatg accatatttt
    17881 agaggaatat aaaatttctg tgccagaata catagagtca aaaggaagtt ctaaatggga
    17941 aatacaagga tacgtatata aaccagtaga ttatgaggtg gggaaaaaat atccagctgt
    18001 attggcgatt catggaggac caagattgac atatggacca tattttatga atgagataca
    18061 ggtatttaca agtgcaggtt actttgtatt cttctgtaac ccaagggggt ctgaaggtcg
    18121 tggcaatgct tttgcagata ttaggaaaca gtttggagat attgattata tagattttat
    18181 ggaatttaca gatactgtac ttgaaaaata tacagacatt gataaaacaa aattggctgt
    18241 tgaaggtgga agttatggtg gatttatgac gaattggata attggtcata caaaccgttt
    18301 tgctgttgct tgtgctcagc gttctattgc aaactggagt ggcatggagg gtacaacaga
    18361 tattggttat tatttctgca aaggacaaac aggtgcttct catatggaaa accacgagct
    18421 tcaatggaaa cagtcacctc ttgcttatgc tgataaatgt gttacaccga ctttattttt
    18481 acatggtgaa aaagactata gatgctatat gcaagaagca ttccagatgt tttcagcatt
    18541 gaaaattcat gggtgtccta caaaactttg tctatttgaa ggagaaaacc atgaactgtc
    18601 tcgttctggt agaccaaaac aaaagctaca aagattagtt gaaatgctag attggttttc
    18661 ggtatatata aaaaaagata acataggaca gtagaaagga gaatataaaa atggaaaaaa
    18721 taaagattga aagttcagat atttttgaat atatattccc tcatgatatt tcttgttcac
    18781 ctgatggaaa gcatattgct tatattatat caaatatcaa cgaggaaaaa gactgctatg
    18841 aacatgactt atatgtgatg gacatcaaaa cagaaaaaca aatacatatg actcaaacaa
    18901 aagatgtaac atcatttagt tggatttcta atacagaact actttttaca tctaaaagaa
    18961 ataagccaaa agcaagtaca acagattttt acactatttc tatagaagga ggagaagcaa
    19021 aaaaagcatt ttctattcca aaagcttgta gcgtacctgt atcacttgga aataaattgt
    19081 ggttactgac aacaaaaaat ccaacggatt ctaaaaaatc agaaccagat agggcagtag
    19141 agggtgtaga ttattggaca tttacagata aaccttttat aagagatgga gaaaattttt
    19201 ctcaaagaag acgtgtaaca ttagaattat atcaagaagg tgaaaatata acaaaagcca
    19261 ttacaccaaa attttgtgaa gtagcaggtg tagacgtttc ttctgataaa aacagaattt
    19321 tatatactgg tcagatttat gaagattgtg caactccttt ttctggactt tgggagtatc
    19381 atatagacag tggtgaaacc aaagaacttg taccacaagg aaagtaccaa ataagtttgg
    19441 caaaatatat tggcaaagat aaagtaatgt tgcaagcttc aacattagac cgttctatta
    19501 cacagaatca tgatattttt atacttgatt tgagtactag tgaaataaat atgattgcta
    19561 gtccagatgg tatgtatgct acattactgg atgtagatgc agtatatggt ggtggacgta
    19621 gtaataaagt tataggagac aaatttattg gtgcaagaat ttgcagaact atgacagaat
    19681 ttaatgagtt tgatacaaag acaggtaata tacgtatcat cacaaaagta gatgctttta
    19741 catcttttga tatttacgac aacaccatgt acacagtaat gttgaaagat tatgagttag
    19801 cagaaatata tagcattgat atgactacag gtacaatgaa aaaaatgact gctttttctg
    19861 aaccatattt agatactcat aaggtttcat tacctgaaaa attgacgttt gtagcaaaaa
    19921 ataaagaaga agttgatggt tttgttatac cgcctataga tgctaaagaa ggcgaaaaat
    19981 atcctgctgt attgttcatt catggtggac ctaaatgggc atatggctat atgtttacac
    20041 acttgaagca gtgtgtaaca tcaaagggaa tgtatgtgat ttattgtaac cctcatggtg
    20101 gtgacggtta tggtgaaaaa ttcttagaaa tggtagaaag atgggggtat gttgactatg
    20161 agcatcttat ggaatttgta gatacttgta ttgaaaaata tcctgggatt gatgcagacc
    20221 gcttaggggt tgcaggggga agttacggtg gttatatgac aaactggata attggtcata
    20281 cagaccgttt caaagcagca gtttctcaaa gaggtattag taacttgatt acagcttctt
    20341 taattattga ctttggggat agaattatga agcagacttg tggagataag acgccttgga
    20401 atcatgagga ggttctttgg aatcattcac ctattaaata tgtgaaaaat gttaagacac
    20461 caacattgtt cttacatagt gatagggatt atagatgttt tatgggggat actttccaaa
    20521 tgtttacagc attaaaacag cttggtgtag atacagaaat gtatttgttc cacggagata
    20581 cacatggatt gtctagaaat ggaagaccat ctaatagaat tgcaagagca aatgctattg
    20641 tagattggtt tgaaagatat ttataataag ggggttattc tatgagtgat atgttattat
    20701 ggtttagtgt cgtattagtt ttatttgcta ttggggattt aattgcaagc aaaacaaaag
    20761 caaaagtatc agctgtattt gttacactac ttttattttt gattctattt gtcacaaaag
    20821 caataccagc tgatattatt gaaaaagcag gtatgaccgc agcagctagt tggagtgttc
    20881 caatgattat gtttagtatg ggaacaatgt tgaatgttaa acaatttata gacgaatgga
    20941 gaacagtatt gacagcatgg cttggaattg tagcagttat agtctgtgtc tcattatgta
    21001 ttcctttgtt tggaaaatca acagtattga caagcatacc agttataaat ggagctttac
    21061 ctgctactac tattatgaca caagcagcac tagaaaaagg actgacactt gcagcagcta
    21121 cagcaacagt tgtatttgca attcagaagt ttattggtac accaatagct tcaagagcag
    21181 cgttacaaga ggcaaaccgt cttttagtag aatatcatga agcaaaatca aaaggcattg
    21241 atttagcaaa tgttgatact gataagaaag aagcagagaa tacaggcaca aaagtaaaac
    21301 aagctttctg tgaaaaatac gataaatatt attctacaaa tgtttgtata ttttttatag
    21361 cattattctc ttatctaggg tatgaacttt cagagattat tcatgtaaat tattctattg
    21421 tatgtcttgt tgttggtgtt attgtaacac gtattggtat tgtaccaaaa gacattttgg
    21481 aaaaaggaaa aatcaaggga tttatcaaca tggttgtgtt tgcagctgtt attccttctt
    21541 tagcaaaagt ttctttgaca gatttaatta gtctttttgt accaattgta ggtatgtttg
    21601 cagcttctat cattggtata ttccttatga tgaaggtgtt accaggttgg aaaattatcg
    21661 gttctaaacc tcttgctttt ggagtagggt tttgtcagat gttgggattc ccaactacat
    21721 atttaatttc aaatgaagtg tgtaatgctg ttggagaaac ggaagaagaa agagcatatt
    21781 tgatgtctaa gattatgcct aagctggtag ttggtggtat ggcttgtatg atttctattg
    21841 tggtagctgg tcttatggta ccaatgttgt agataggttt catagttaaa aaagtggtgt
    21901 taatttatag gagaagctaa aaagtagtat taatttataa ataaagctag aaagtcagta
    21961 ttaatttata aacgaatttt atattagtta atttattata agaatatttt ctttttagca
    22021 ttataatctt gattttatca agaaacagat tttttatttg ctattctaat agttacagtt
    22081 tatttttatt ttctaaaaca aaactttaac ttgatttatc tataaatagg gtatttaata
    22141 atatttttgg aaaatcttta gaaagaatta aaaagaggag aaaaaaggga gtgccacaaa
    22201 gtgaactttt tagttctaag gcactctttt ttgtacgaaa tcgaatatat tttcaaagtt
    22261 ttaaaagtga gaaagagact tatctctagt ttgagatagc caattttaat tattaaaatt
    22321 attttttgtt ttatttatca aagagtattc gtgttttaga agttagtatt ttttatttta
    22381 tatatacaag gttttccgtt tctaatgttt tcttttttaa aataattagg gtattcaatt
    22441 atggtaaaag gtggatggta ttttgcagtg atattattta aagcacagta ttgaatgttg
    22501 aaattctcac attttagagt attatctttt ttaatcaaaa aaatcttcta tacttatagc
    22561 aaggttactt ctgcaaatat tccatgcatc ataatatcca aatttaaatt tttttaatat
    22621 agagtttacc tctagtctac actcttgaat aactctttcc tctatccaaa ttcttataaa
    22681 ttcatcccat ttattactat ctatttatta ctatctaaat tttttagtat gtttgtaatt
    22741 agaaatggat ttattccttt atgtttttta taaatagttt ataacttaat ttatcatcaa
    22801 acaaatcatt catacaggat tcctcttttt tttagatatt caattcttac ttttaataaa
    22861 tatttaatac atcctatctt atgtggtttt aaaaagtgtt tatagctatc aaaaatctct
    22921 aatatttcat tcatatttat tttgtcatag taatatttta catcttttat attgacaaaa
    22981 aagtgctcta agtgtatagt gtgtatataa caacatcaca ctgaaaatga taaaaagggg
    23041 gtgataaaaa atgaaagtgc tcatttctaa cacatcagat aagccattat accaacaaat
    23101 taaagagcaa attaaagaag caatatttac tgaagaactg aaagaagggg atgcaatgcc
    23161 atccataaga aattttgcta atgatttaaa agttagtatt ttgactatta gacgagtgta
    23221 tgaagaactt gaaaatgaag gctttcttac acgccaagtt ggaataggaa catttatttc
    23281 aactggaaat ttagaaatac taagagactc aaagagacgt atagttgaac aaaaaatggc
    23341 agatatgatt aaggatgcaa aagcactagg aattacacag atagagttac aagaaatgat
    23401 ggatattcta tatcaggagg attaatatgg aaaatatttt agaagtttat aacttaaata
    23461 agacttatac cgatttttca ttatctaata taagctttgc attaccagaa gattgtataa
    23521 ctggatttat aggtgttaat ggagcaggaa aaacaacaac aatccgttcg atattggatg
    23581 tcgtaaagcg tgatagtgga aaaataaaaa tctttggtaa agatttcgat ggaaatgaga
    23641 aggaattaaa aaatcgaatt ggagttgtat ttgatgattc atatttctat gaggagttgt
    23701 caatggcaga aatgaaaagt attattgcac cttcatatga taattggtgt gaagaagatt
    23761 atcaacaaaa tatgaagcgt tttaatctta acccaaaaca aaagattgat acactttcaa
    23821 aaggaatgaa aatgaaattt gctttagcat tagcattatc gcataaagct gagtttttaa
    23881 ttatggatga gcctacaagt ggtttagacc cactaatccg tagtcagata cttgacatac
    23941 taacaggata tatgaagaaa tgtggtcgtg gtgttttctt ttccactcat ataacatctg
    24001 atttagacaa aatagcagat atgattgtta tgattgacaa tggacgtatt atattagagc
    24061 gtgaaaaaga tactctattg gacgaacata gaaaagtaaa aggggatatt caatttctaa
    24121 atgatgaaac caaaaaatta tttttaaatt tagaaattac aggttatggt tttataggga
    24181 ttacctcaaa aattaatgaa gtgcaaaaaa atatgccaga tattttaata gagcgtccta
    24241 caattgaaga tattatgctt gcatatattg aaaggagaga gtaattatgt tgattcattt
    24301 agttaaaaaa gatattctga ttgtaaaaaa atatgtattg ttgatattat ttattgcaat
    24361 aggaatccca ttatttatat tatggcgttt acctccattt gcacaaatat tgggatttgt
    24421 actatcaatt atattttcag aatttatgct gtgtcagtat ctattattaa aggagagtca
    24481 atattcaaaa gcatctgtat tactttgttc aactccttat cctagacgtg gcttagttca
    24541 atctaagtat gttttatttg caatggtatt tatctattgt acattagttt actggattga
    24601 aaatttactt attccacaaa taggaacttt tgacttgaca tatattttga ttgttttatt
    24661 aataagttct attatttatg gagtttatat gcctattcaa tataaattag gatatgaaac
    24721 aacaaaattc tttttcgtgg tgataatcat ggcttcatca tttgtattac cattaactat
    24781 agctcacagc aattttgaaa ttccatttat atatcagtat ccatccatga tagtgaatat
    24841 tgtattgttc cttttaagtt taattatact gttagcttca atgtttattt ctattaaaat
    24901 ttttagtaat aaggagcttg tataaggtaa gggggacttt tatatgccac atttgccaga
    24961 ttgggctgtt ttactttgta tcttacttcc aatagtatat aaagcttgtc agatatttaa
    25021 aagtaaaaaa tagagtacat atttatattg ccatttttat tgagtaaagt tagatggtat
    25081 gaaaaggtta cttgaaaata aagttacttg gtgtggcaga gtaacatcat aatattatag
    25141 attatatgtt tcttgtgaat caatttgtat tttttaatag ataatatcca gtaattttat
    25201 tttccattga ttatttttca attatgagta tgattgtgtg tattgtatac cattttttaa
    25261 gatgttttta aaaaattata tcgtcaaaat ataaatctaa ggaatcctat aaataaagct
    25321 tttcaatttt agaaaactaa taaaaagtag gaagttaata aaaagaagct gtctcaaaat
    25381 agagataagc ttctttttca ttgctgaaat gacgaaaata taattggttt aatataaaaa
    25441 agagcgcttt atgaactatt tattttgaac agtagataca cttgcactca atttagttac
    25501 tcctaagctt tatgaactaa aagtttattt tgaagcctat ttttattaaa agagatttta
    25561 tttttctaaa taatcatcta tatacagtat tgcgtttctt ttatttattc ataatttatt
    25621 ttcttattaa agtttttcta tattcatatt ttccatatta ctttactttt aattttatac
    25681 gaattatcaa aaataaaata gttattagaa aaaaataaaa gtaattgcaa agcttgcaat
    25741 tacttacttc tatattaatt actataccat aaaataacaa aaaaatcaag tcgagtaatc
    25801 cttcaactta agtgatatac taggtattaa taatttttaa ttaataaaat ataactagag
    25861 gaaaatctac attttctcaa tttctttaat taaattgacc tctaattaag taattataag
    25921 gagaaaaatt atgaatttag caaagggatt agatgtttta aaaatttcat caaatgtatt
    25981 cggtgaagat aaagttatgt atattcctgt aatctacaca gaagatgatg caacacttat
    26041 tgacacaggt cttccgggtc aaggtgattt aataattgat gctcttaata aaagtaacac
    26101 gagctttgat aggttaaaaa atataataat tactcatcat gatatagacc atataggaaa
    26161 cataaattat ctaagagaaa aatctaagaa taatatcaaa gtatatgcat acaaaagtga
    26221 agtcagctat ataacaggag aagaaactcc ttttaaactt tatatgttgg aacaaatggt
    26281 agataaaatt gatgataaga tgcttagtat gctaaatgtt atgggacttg gatttaaatc
    26341 atcatatact aaagtagatg tgtcattaga taaccatgaa aaattgaatc taggtgagga
    26401 aatagaagtt atacatacag gaggtcacac tagaggtcac atatgtcttt atttaaaaga
    26461 gtctaaagta cttattgctg gagatttgtt acaggtagaa aatggagaac ttaagcctgt
    26521 tgatgtgatg tacagcaaca aacaagagtt aaaagatgct attaaaaata taagtaatta
    26581 taatatagaa acgatagttt ttagtcatgg tggattatat caaagaaaca taattggaac
    26641 attgaaaaac ctaattattg agtagtacta tatgatttac aataatttct taaattactt
    26701 aaaattatat ctaaagatgt agaatcaaaa ttaaatataa gtaataagaa ttttgcttta
    26761 aaattatact taagtgttaa gggtgatatg tagtattaca agtattttag aatatagttt
    26821 tttatagtaa ttttaaggtt ctacaatact tcagttgaaa aatatttaac agcatagtat
    26881 aatgggaaag aaaatacttt aaataaactt tagtatacaa agtgaagaaa aatatttaaa
    26941 ttatatataa tattgtagag tgaggtaaaa tatttaagtt atatatcata atacagagtg
    27001 aagaaaaata tttagataat gtaccataat acaaagtgag taaaaatatt taaatcatgt
    27061 atcataatgc aaagcgaaga aaaatattta aataatgtac cataatgcag agtgagtaaa
    27121 aatatttaaa taatgtgtta taatacaaag cgaataagat tatttaaagc atgtattata
    27181 atataaagtg cgtaaaaata tttaaatcat gtatcataat acaaagtaaa aaagattatt
    27241 taaaccatat atcataatgc aaagtgaaga aaaatgttta aattatgtat cataatataa
    27301 gcagagtgaa gaaaaaaatt taaataatat atcataatgt agagtgagta aaaatattta
    27361 aatcatgtat cataatataa gcagagtgaa gaaaatattt aaatcatgta tcataatata
    27421 agcagagtga agaaaaatat ttaaataata tatcataatg tggagtgagg aaaaatattt
    27481 aagttatgta tcataataca aagtaaagaa aatcatttaa attatatatc ataaaaataa
    27541 tatgaaatat tgaacactca taatattaga gactttaata ttttaattga taggttatat
    27601 tatttataac attaaaaata caatttacat aaaatagaca tatgaaaaat aaaaaattat
    27661 ataataatta tgggaatgag gttctccctt ggatgataat atcctaaact gccaatgagc
    27721 tgatgacttc tatgatatca tagatgccac cagctttttt tgttgtttaa atcaataaaa
    27781 tggaggtgaa gtacttacta aatttttatt ttttaaattt gaagaaatat ttaattaata
    27841 gaaaaaatag tagattatat gttaattatt ttattaagaa tgggttaaga gtgtacctat
    27901 atcctatcaa tttaaaaaac aattatgata gtcattacat tgactacagt tgatgcaata
    27961 aaactttcaa aaaatcttat gatgcaaata gaaaggaatt aaaatgatag aaaaatttaa
    28021 aactttaata tggattaaaa tgataataag aattaaaagc gtttataaaa catatggtgg
    28081 actatttttt ttaggactca taggtatacc agttggtgca attataggtc ttatagacac
    28141 catatttgga acggttcttc taaaagttac agatattcga gaaacatatc caatgtatct
    28201 gataccattt ttagcagtag taggagttgt tattgcttat tgctatttta aatttggagg
    28261 aaaaagtagt aaaggaatga atctaatatt tgaggtaggg catggagaag aagaaattat
    28321 tcctttaaga ttggttccat ttataatatc aggtacatgg ttaacccatt tatttggtgg
    28381 tagtgcagga cgagaaggag ttgctgttca gattggtgca actttttcac attgggtagg
    28441 taaaaggttg cctataaaaa atgcttctag tatttttcta gtaactggta tggcagctgg
    28501 ttttgcagga ttatttgaga caccaatagc agcaatacta tttgctatgg aggttttggt
    28561 tgctggttca ctggagtatc aatcgctttt tcctgcgttt actgcttctt ttacagcaag
    28621 tgcagtatca aaagctttag ggttagagaa attttctttt gcactttctt ctgaagttgt
    28681 atttgacttg tcaatatttt ggaagcttat tgttttagga attatttttg gaatggttgg
    28741 tggagcattt gcatggtgtc tgaaattgtc aaaaagaaaa atagggaata gattaaaaaa
    28801 tcctatgata aggattgcta ttattggagt atgtcttagt gtattattcc ttttatttta
    28861 taaaggaaga tattcaggtt tagggacaaa tttaattcaa aatagtttct atggtggaga
    28921 aatttattca tttgactggc tgttaaagtt tatacttaca atactgactt tgtcagcagg
    28981 ttttcaagga ggagaggtta cacctttgtt ttccattgga gctagtcttg gtgtattgtt
    29041 agcaggattt tttaatttgc caattgaatt agttgcagcg cttggctatg ctagtgtctt
    29101 tggtagtgct acaaatactt tttttgcacc tgtatttata ggggcagaag tttttgggta
    29161 cagctattta ccttatttct ttgtagtatg cgctatttca tatatattta atatggataa
    29221 atctatttat tcactacaaa aaatttcaac aaaacaataa ataaaacaac ataatgtatg
    29281 attagaagag aaagaatatt agagaaagga tagggtagga atatgttgac aagtttagct
    29341 ttgatttttt tattaggaat ggcctcggga ggtattttta agaggataaa gttacctaac
    29401 ttattgggaa tgttacttac aggaattata ttaggtccat atgttttaaa tttgattgat
    29461 aattcaatac tagatatttc ttctgacctt agaaagattg cattgattat tatattaaca
    29521 agggctggat tatctttaga tataaacgat ttgaagaaag tgggaagacc tgctgtactt
    29581 atgtgcttta ttccagctac ttttgaaatt atcggaatga tagttttagc accaaagtta
    29641 ctaggcgttt ctatattgga agcagcagtc atgggtgcag tagtaggagc agtttctccc
    29701 gcaattattg tacctaaaat gcttaaatta atggaagaag gttatggtac agaaaaaagt
    29761 attccacaga tgcttttagc aggaacttct atagacgata ttttcgtaat tgtgatgttt
    29821 acagtattca cagggttggc acaaggaaat agtatatcag ctattagttt tttacaaatt
    29881 ccagtatcaa ttatattagg tgtaatagct ggagcagtga ttggaatctg tttagcagta
    29941 ttttttaaga aggttcatat gagagattct gctaaagggg tgttgctttt aagtatctca
    30001 tttttaatga taagtttaga gactgcttta gagggtattg tgccattttc tggattatta
    30061 gcagttatga gtattgggat tttccttcag ataaaatatc gtgtagttgc aagaagattg
    30121 tctataaagt attcgaaact atgggttggt gctgaaattc tcttgtttgt tttggtaggg
    30181 gcaacagtag atataagtta tgcatttaaa gcaggaattg gagctgtaat tttaatattt
    30241 ggagttcttt tattccgtat ggtaggagta ttcttctgcc ttattaagac aaatttgaca
    30301 ataaaggaaa ggttgttctg tatgattggc tatattccaa aggctacagt acaggcagca
    30361 ataggaggtg taccacttgc aatggggatg gcatctggac aacttatttt gacgttagca
    30421 gttctagcta tacttataac tgcacctctt ggagcttttg gaattgatgt aacttataaa
    30481 aaattattaa cttctgtaaa aggcgagagt aagtaaaaat aaagattatt ttaactggta
    30541 agttatattt tggaaaagga ttatactatt gaatacaata taaaaaaatc atttgggaga
    30601 ttaagaaggt agaagttaag aacagatttt aaggtatgtt atgattatta gaattgattt
    30661 tgtgaaatta ttattgtaat atttaattat atagataaag aagcggagtg ataactatgt
    30721 gtttaaaaaa attatcaaaa ttagagttag ttattatgaa atttatttgg aatttagata
    30781 taaaaaccaa ttcatatgag attattgatt atatgaaaga agaacataat ttaccagaaa
    30841 aagtagcttt aaaaacttta tcaaaactat caaagaaaag attcttatat gttcaagaaa
    30901 caggcaagtg tatgtattat acagttgcaa taaaagaaaa ggcatattta gagtttatat
    30961 caagaaatgt gcaaaatctt ttgaagaata attttataag gaatttatta gtatcatttc
    31021 acgaagagga gctaacagag gaaaagataa agtcgttaga aaactgggta gtaaattggg
    31081 aagaagctta tgtataaatg ttattatttt tattacaatt tagataattt tggttttgta
    31141 agctctgcaa ctatttttag atggttgcag agtttatttt tattttttat tcccttaagc
    31201 aatacttaaa agtaaacgca tttatattta ctaacttcaa ttacttctaa tacttaaatt
    31261 actttttaaa aatattttga tatgtcatct ctatagtaat ctagaacttg tttctattct
    31321 ttatataaag tttttatgaa tgatatatat aatattcgtt catttgatta aaaataacaa
    31381 aatattaaat aattctactc tgatagtttg ttaaaaaaat aataaaaaat attaataaac
    31441 aaaaaaaaat tatcttaaga gaggagaatg ttctaaaata taaaaaggtt tctagatttc
    31501 ataaaagata ctattttagt cttgaaaata tttagtttga aaagatttta atttaatgat
    31561 tgattaagtt
//
LOCUS       DAMJXI010000039        30868 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.041, whole genome shotgun sequence.
ACCESSION   DAMJXI010000039 DAMJXI010000000
VERSION     DAMJXI010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30868
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.041"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            280..735
                     /gene="smpB"
                     /locus_tag="PC465_002384"
     CDS             280..735
                     /gene="smpB"
                     /locus_tag="PC465_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HDF2649675.1"
                     /translation="MAGKKILATNKRARHEYFIEETYECGIELKGTEVKSIRQGKVNL
                     SDGFASVDNSEVFLKQVHISPYEQGNIFNVDSLRVRKLLLHKHEIRKLIGATTIKGYS
                     LIPLSLYLKNGKVKVEIALAKGKKLYDKRQDMAKKDAQRRIEREMTGKY"
     gene            893..1242
                     /gene="ssrA"
                     /locus_tag="PC465_002385"
     tmRNA           893..1242
                     /gene="ssrA"
                     /locus_tag="PC465_002385"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1908..3167)
                     /locus_tag="PC465_002386"
     CDS             complement(1908..3167)
                     /locus_tag="PC465_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDF2649676.1"
                     /translation="MIECIPYPGYRDRDGYGQINSNKEGTLRAARIVLEERLQRPIRN
                     GYQAHHTCYNRCCVNPSHIEERKVSENILDKYFNDRPEINEIVLTKESVYLTKYLLNN
                     MNNSEFNYSIEEIAKFLSIPLELLLYIKKGSVWNYIYLTNAEKVEALHKLEIFFPKEV
                     CIEANWGSEKYCPVVHKNNKQIKASRYSYDTYTNTSSSGKYILHNCDNPLCIRASHLR
                     TGDQKDNMNDKVQRRRTNRDYYLYNQEIIKKIVQLRDVENYSFSKIGREIAILVKRDK
                     PYDHKTVISIYKNYKYTRREELKEKPPTQRELLNKHIDTLIDLKHNYNYSLRQISHKL
                     GSNLIGKPFDLNVIGQVYKEHISKQNLIPPKSSIKLLEENITEILSMLDCNISLREIA
                     NRLTKKLNPNKPFHHNQITKVVNKYKK"
     gene            complement(3266..4432)
                     /locus_tag="PC465_002387"
     CDS             complement(3266..4432)
                     /locus_tag="PC465_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF2649677.1"
                     /translation="MATKIANGEGSIGKYKDGWRSRIMIGYNEDGKPIRKEFYGKTQK
                     EVKDKLDAYKKQYYLSSDISDDKITLEHWFYNWLFKYRIKDLKPKSFERYESIYRNYI
                     KDTDLVNVKLNDLRVSHIQKYYNRLLDSNKSIPTIRQINTKLKTCLSEAEKQGLIQRN
                     YCTMVNIPVEKKENKIEILTLEQQKSFIKAIDGHKLEVLFLLALGTGLRLGELLGLKW
                     FDINFKNSNLTVKRTLQRTYFIDKNGDRELKVLEQEPKTSNSYRTVPIPKNILNKLKE
                     HKVSQNTDILKAGELYRNDNYVFCNKLGVPIDDKRPLRNLKSILNSLDIEPIKFHGLR
                     KTYATRLFENNVPPKAVQVLMGHYDISITLNIYTQVMEDKKVEAVEKLDKIFSL"
     gene            complement(4422..5174)
                     /locus_tag="PC465_002388"
     CDS             complement(4422..5174)
                     /locus_tag="PC465_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDF2649678.1"
                     /translation="MNKSYIPKYTHKFPTNLPHGDKKYTLTYIRRMISEFVYDMGNLE
                     NNPFTFPEVQTLLDGITVGGHKLSDQNQILNIKSSWDYVIKLSNKEKLSLNKDTICSI
                     HKIVAKDEALIVGDFRNGNIGIAGTTQYECIEPTLLNDLFVNDINIINKITNPLEKAI
                     IINLWLSYCQFFYDGNKRTARLTSNLILISNDIGVLSIPAKHKQEYNTLMLNFYETLE
                     GDEVIKFLLEKCITFFDEYNYKSYKELFKNGN"
     gene            complement(5266..5756)
                     /locus_tag="PC465_002389"
                     /pseudo
     CDS             complement(5266..5756)
                     /locus_tag="PC465_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(6007..6771)
                     /locus_tag="PC465_002390"
     CDS             complement(6007..6771)
                     /locus_tag="PC465_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2649679.1"
                     /translation="MQIGKNLKKIRKQKELTQIQLAEISDISRNALINYENDKRIPNI
                     DTLSKLAKALKIEKTIFYFDIENEVITNEDVLYFLQSLFPEEYYSFDEFLNAISNLME
                     DDDIRITSSLLLGAWSDKDQYYKLGEKLELNENQVYNWILSDCISNTELDFSLHPDDI
                     KEIIKNDVLTKQSIDELLDIGLSEENIETIYDYFSDSTDNGSNIRLKKLISQKENITI
                     KNNDYFKLLQENNELKEKNEKLENTLKEIKKLLTKI"
     gene            6907..7555
                     /locus_tag="PC465_002391"
                     /pseudo
     CDS             6907..7555
                     /locus_tag="PC465_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891536.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
     gene            8179..11658
                     /locus_tag="PC465_002392"
     CDS             8179..11658
                     /locus_tag="PC465_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HDF2649680.1"
                     /translation="MGKIEPNQEDRIYEDLYQGNSAEGKVCEWIEEAINDDCYVGQHR
                     FKIETRECDIAMVIPNRGILIIEVKGYTVEMIDHMSSNFIIHVKKEYENERFKTGERH
                     PAEQANDYVFTMMRDFSGFLKRNNICLPICKIGRMAAMPNMTDKEYEELYLDYCYSTK
                     LVITKDWFKNKNIFYHRFINALNIIFNSISSEVDFDDSYYNIARRYILLGERKKYVDL
                     CKEQLKREEELGIDFIIDNTNEEVDQLCKSNEVNDEEMELIKFSSVLQEELTESHKLS
                     KIIPYSKLRIVKTGCEIEPLLEICCNERKEGIKQFLILVNFTRDEKEKILLEYEKRFL
                     NKYKENELLFLFNMYFIDLSNDDTSIDNLFSNHDNIEIINGERIEEIVKIKPDNFIVQ
                     EFTPKDLLDQALWNILCIADNFTSFNFDQYIVEHSPLRQNIVVTASAGTGKTYTMVDR
                     VSFVAHMEIIYRNSKESISDLISMITFTNNSTDEMKERLMKHFMQYFELTHNKVYMDL
                     LEQLGRMKIKTIDSFTKYILSKFAHLLGLSNSFSLKSGKFELENILRKYINDEITKEI
                     IDDFHNINIYEIANHILALRSFLINRKIQFDKIKHASIVGPDVGKGTIRMKNFIESVL
                     ISTNSEYDSFNCSQNFISMNELVIQLEKVKNKLIKTSCVNNTKENYEKYLFIDEFQDT
                     DNKQIQLIRFFADYFNIALFVVGDEKQCIYGFRGAERTSFLELTCVDTNFQQRNWISC
                     FLRKNYRTEEPLVKKINEVFSKMPNDFFPYQNKDKLVAQKGIGRIYSGCYEQFKYSEN
                     NLIELVDNCVKRMKKNNEDGQIAILTRNNYEVDQIRALFGENKEYEIKFDNGGLFYNT
                     DAVIDFYKLVEFLMDTEDGAKRYSILETPYSDFRIKESKIKLYQAYEKMDVETFEIIR
                     SGNNHVSLRKYYDVLYNYGKKHPNLKNSPSLKILRMIVNEIKPWEHYVPERYKTVDFN
                     DICNQNKLIEARNEYRQNLFQLFQKLIDDNKTDYLTLNKIHQILTIGIFAMQDIDIDL
                     PKNNFFGEKISVLCTTVHKSKGLQYHTVIMPFTMNDITESRGSTQFIYREDTNEIYMQ
                     LKEADGKCLIYESTNFDCENNKKNETIQSEELRILYVALTRSKKFFYFMVDEERFEKN
                     NTSKKNCWAHYLM"
     gene            11675..14911
                     /locus_tag="PC465_002393"
     CDS             11675..14911
                     /locus_tag="PC465_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649681.1"
                     /translation="MKIYTYKNSVQLKDAIFWNEIEGAPHFCSSEVLAIGMRKFYGRN
                     TFPCISTIDLLIKELYPNWLKSHSDIERYKDISKLINELNDSSTEGLRQAFVKNKKSI
                     LDSCKYLIETEDLLLKDYYNKNIFNKFSAINDIQEVFKEKILKRLLEQIYIDGNKNYW
                     KPEWIDTLWVKSKLSEVIHKCVIKEISDIVKNTEEKSLNHNYDEGHIFEIFDELFDQH
                     GLFNISDKTLEYWKFNSKDDLLDKIGYSSKELEYVRNLATTECKSYKTIVIHGVYHLN
                     PIHLRLLRDLERDHNVIVLNCYNKEFNHIYEFWNDIYDHLIKIFQIPKNNIKIDSHDS
                     ANHREVGSIFAEVVNGVINKQSNFFKISRNEFGPDLNLNSKDIDELFNHNSSQDIRYI
                     LNKSEAIIQNYEDEDEREYQKILIDTSKELQKELCHRSKILIKYDSTMQFVNKVCNIF
                     DETKNKKGIRSVGRMKEQFYGSKGTEMNKIFQVFYPDEFKVKPFLSYPIGQFIYAIHN
                     MWDLKNHKLILNSRDLAECLNLDVWHDIHPLEVFESLRFYIGIDKEPNGMNVKDFIDR
                     IKKLIYFKERNENKMKNLDNLSYLNLTIDQYNRFIQVIENINEIANKIFCNKSQTSKK
                     HFMDLLEILNDEKAWKPLLEEEKRLMDEIKNQIIHIDDETNKTDLNTIKDTMAYYLDS
                     KEGTDINWLVRDFEQLEGDILSEAANYKNNTLRQKCYHLTMLSNENMINCDIDNLPWP
                     LSDDFIISKNISSFIHTICINYAKYKRCLLFQGLYYLINNPIISLKLSYIENQGEYKH
                     TPYYILNMFMNIGKDFDQSNCRNIESCTSPINKEPKKRFKIDKKWHKDAIESFSCCPY
                     KFMYGYVINDAAKHYKDELQVKMYLGEIIKYYISIAWKKILQYHKKLLLDQKFNLLKK
                     WTAGERLDCLEKSLPETLEPIYGNYFIKSEINKIIVDNLEYLKNKRIDNKRVYFTEEC
                     KIYEVDRELYHCWIGKISNHNLYVTNKNKIINIRNRLNLLNANEYINDYILGINDGWY
                     FKKDNIVVEGGYKVSEHACRYCSYNKICCYQYRIKPIHLLHSKEDLID"
     gene            complement(15023..15406)
                     /locus_tag="PC465_002394"
     CDS             complement(15023..15406)
                     /locus_tag="PC465_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DndE family protein"
                     /protein_id="HDF2649682.1"
                     /translation="MRFKLKTSTQTKEIFEELGSRMNLKPFALCKLAISMSLSYSESI
                     ESYENIDNNGLELNRQTITNQYDTLFKTLFEQHIGRHLSDNEYFPNQVKLHIDRGAIM
                     LKNRYNYSSNLEHFITQIIQEDNNL"
     gene            complement(15409..17568)
                     /locus_tag="PC465_002395"
     CDS             complement(15409..17568)
                     /locus_tag="PC465_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2649683.1"
                     /translation="MKINKLVLKNFRSYEEETTFNLNTTSDKNIILIGGKNGAGKSTI
                     FEAIKLCIYGPMAYKYQGFNASYISQVKSNINNNSLINSKIDTLVSVDIEISEGTEEN
                     IYTLIRQWTFKDEKLNETFLVYKNFSTTPLNADELNYFENYITSIISPKIFDFFFFDG
                     EHLYDFFVGKNSNIHLKESLLSLCNFDTFDILKKVLISTNRSNKNVSDEINIVKDSYL
                     NLEMEINTLNSQEEIFSYELQKISNEIEKLQQEQLEVKKEFRKKGGILAEERETLNSR
                     IAELEGKRFIINQNIKEFCNDILPFLIVKKQISNLEKQLKTENDILLYSRLKDKLNIE
                     YIKNLLSDKIMPSALDEIALTVSEALTEDIKPDSYEENFKSIHNLSDDESRKLLSLIN
                     TILNFDNNSIINSFEEHRSISNELADIRHKLNTSLKDESLNTYINDMSNLSSKIDSLL
                     GSKNLLVTSLDKLKLEIAETKSRRDKSKAKYIYLLQHNNIVDISTNLILMLDEIVTTL
                     TETKIKLIQDNFMYIFKKIIQKDNFISHIDINVNFDISLYINKIYNSLELENLAKNIG
                     IEGMEKKLGKLFFDDLFNLYSVEDKYELFNVIRNNTQSTFLNLRTKVDIDEFSSGEKQ
                     IYVLCLYWALLKSSGIEIPFIIDTPYARIDDTHRNSITSEYFSTISHQIIILSTNTEI
                     DEKLYKIIKPKLSREYLLEYDSKNKKTIQNKGYFFEV"
     gene            complement(17555..19021)
                     /gene="dndC"
                     /locus_tag="PC465_002396"
     CDS             complement(17555..19021)
                     /gene="dndC"
                     /locus_tag="PC465_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA phosphorothioation system sulfurtransferase
                     DndC"
                     /protein_id="HDF2649684.1"
                     /translation="MAVNYLDNNNLENLYDEMQAVYLNDDRPWIIGYSSGKDSSCVVE
                     LTFRMLKRLPKEKRHKEIYVISSDTLIENPIILDYLKNNIDKINESATEHDLPISAQI
                     VYPELNDSFWANIIGRGYPTPKSIKYRWCTERLKIKPSNKFIKEKLEQKDVIVLLGVR
                     KEESSARKSRIEKREIEGYLLTPHETLRGKNKLAYVYTPIVNFSTADVWDVLYHQNDN
                     FIDFGGEFGPSPSTSWGTDAMELFQMYMKGSGDSDECPFIADEASAKSSCGNSRFGCW
                     ICTVVKEDKSLNGFIESGHDELKPLLEFRSWLISERDKPKNRKKHKRNGSVIKKDGKI
                     MFGPFTFEARQTILRKLLETQLEMQKFYPDLQLIQLGELKAIDEIWDNEEDLTGNILS
                     KIYKEVVGKNLPWSEYKKPVFDDLTLNIISEKCSEYDINIDLFNKLIIDTNKYKYFSN
                     NTKLKTSIERILNQQWLHQDIIEKIEEEGNKELKYENK"
     gene            20099..20344
                     /locus_tag="PC465_002397"
     CDS             20099..20344
                     /locus_tag="PC465_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HDF2649685.1"
                     /translation="MLIHTKNKTFDAICILEKIEKDLNIEELVRCHKSYIINLNYAEN
                     IKSNTAILDSQEEVPISRYRYKDIKEGFLKFIGDRIC"
     gene            20338..21731
                     /locus_tag="PC465_002398"
                     /pseudo
     CDS             20338..21731
                     /locus_tag="PC465_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
     gene            21991..22248
                     /locus_tag="PC465_002399"
     CDS             21991..22248
                     /locus_tag="PC465_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649686.1"
                     /translation="MSKKISESIENSGLRVAENKSDGSFVLSLGNLEYTKEQPSQVLH
                     YSITKDKKDTKEILSIQCVKDFSYNEKLSEDDKFIMAIYNI"
     gene            22253..22432
                     /locus_tag="PC465_002400"
     CDS             22253..22432
                     /locus_tag="PC465_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649687.1"
                     /translation="MIHIEISEKEFFRKIEEVFDKGEENVEVDNLGDIKIQVKKFDDK
                     TKPLELKLIKEFKLK"
     gene            22444..22638
                     /locus_tag="PC465_002401"
     CDS             22444..22638
                     /locus_tag="PC465_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HDF2649688.1"
                     /translation="MRKYKAILLTLIISIIAIIGFIIYNNYFRKWNEAEKYIDKYMTY
                     QGVSSDDIERITKEKYTKEN"
     gene            22872..25424
                     /locus_tag="PC465_002402"
     CDS             22872..25424
                     /locus_tag="PC465_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2649689.1"
                     /translation="MGIYLKMSLAYLKKNKLRTLLLIIGVMLGVMLIFGPSVIKDSQN
                     ENNVVAIHELYSGYHVEFSDLTLDDAKKLETDEKVSKGNSVQNLGRISDKKGNSFILT
                     SSNEEYLKSRYNKIIEGRLPKNNNEIVLEKKALEAMNLSEGVGSTLNLTIKKNYKDTN
                     GSNQLFSINKEFKIVGVMEKPKGYYDVVWQYEAVTYGNDETNNIIPNDAISYNSILSF
                     KSGWRNIEGECDYLMKKYKLGQKSFLPNVPLVRELRYVEDDKSDPNVFKRNVLITTVS
                     IIFIFNIFNITLNQSVKEMGLFRLMGAKKRNVRCMIIYQALIITIIGILLGLVAGVTY
                     SYIGISNYNEVLYSEAGLNPKLYINNEIVIKAILVGIISVFISCIIPTFKIGKISPIE
                     SIINTDKIKNHRSRLGIDRLVSKIFGFYGFMGLKNIGRNKVRAAISMLSIALGGYIFI
                     TTFSSMQEEVNSKIEDMQNRYNITMQFGVNADPQISKYTDSDVENIEKIKGVKSIHKI
                     QITNGMFTFNNKDINKEFTTYNGVEKKEIMEDKLVLKLYDDYIDEKLNDFVEEGSLDD
                     IKKDTDGYPNVAVYNYFYDIVDDHTIKPIFKELNIGDIITVKIPVEENNTIVYKEMKV
                     RVAVILKDEWIAMGDGDFMPDLEIITSNIHSKNITGEQKYTQLGINLENPYDEIVNNE
                     IQKISRSIPGSLFNSRLSYHEMSESIYKSYIKSQIAIIALVLIIASINIFCTIRTNLL
                     IRKKEISTLRALGVSLKNMKKMLIYEALAYAVFSFIIAMIPSFINLVKFTNWNNDAYI
                     NYGIENFMSFTFPIKESLLFFAISVFVCLIAVVVSNRDFESMNIIEGIKENE"
     gene            25441..26103
                     /locus_tag="PC465_002403"
     CDS             25441..26103
                     /locus_tag="PC465_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2649690.1"
                     /translation="MKMLKVIDIKKIYGKGENEIKAVDGITLEIEPHKFSAIIGQSGS
                     GKSTLLHCMAGLDKPTLGNVFMDNLDLYTLSDEKLSNLRSKEFGFIFQNYNLIPVINV
                     YDNIVLPILIAKGKIDNNYINDLITKLGLESQINKFPNELSGGQQQRVAIARSLANKP
                     SIIFADEPTGNLDSKTTNEVMNLLKYCVNEYKQTLVMITHNDEIAKMADCIITISDGK
                     VI"
     gene            complement(27116..27687)
                     /locus_tag="PC465_002404"
                     /pseudo
     CDS             complement(27116..27687)
                     /locus_tag="PC465_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427525.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
     gene            27956..>30868
                     /gene="cbpA"
                     /locus_tag="PC465_002405"
     CDS             27956..>30868
                     /gene="cbpA"
                     /locus_tag="PC465_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding adhesin CbpA"
                     /protein_id="HDF2649691.1"
                     /translation="MQQKCKKKALSMILSISMGLGSVASFNASNTFADTIEESTNAGN
                     AEGDTNAGNAEGDANAGNAGGDANAGNAGGDTNAGNAEGDANAGNAGGDANAGNAEGD
                     ANAGNAEEDSNAGNAEEDSNAGNAEGDMNALVVEEATAEDPTSVGDFKISGGEINVDF
                     KFASGVLTILSGKQMTIQNNNPNTPTTHRIVIPKDVKAELIFDGVNIKTASNSPFTLT
                     PDKDGGAYAHVILQDGSENKLESGDVYYPGMRAGKGTTLIIDDSVVNRDIEGEFIVPE
                     GGKIPRDVTLENGDKLKKGDRLTLLDSNNRGSLKVVGNYYSAGIGGGNTESGGNIIIN
                     GGAITAIGQESSRNTGYGAGIGGGGNGSGGDITINGGTITAKGAYHGAGIGGGYYTTT
                     KNALSPSVVDPSTGSGYSGNITINGGLSYSYGGAHGSAFGDGCVNPGTNRGYRILVTG
                     GTILPYMTGVGDWIFDLSATTGDVIVTGGSLKATTFKSLGGAVAYGDLEKKTKVFMNK
                     ISLTYLGQDKVSTTLVDDFKMLIDGKIYPYGAPSYTDAQGILYLWFSDKFTGSEVSVN
                     LVVIDKITGEVLKPDDFYIKDIGSGSQFLKQYEEFTIDDTPPYLIIKRYDGLPFEEDV
                     EKSFLDWLLKDGGIPITTPKGEKLTDKKFMTISSQRLNEETMEPDINLGSDDLTKQVD
                     AGKYQLSITSTQFSSIYPFKDAYWGHRAYYKAEIIPADTETSLVVEESKAKTDVFKPT
                     DTFTLNVTISPDKKEGPDCASPRGYVQFYINGKEYKDPVELKTHNKGSESHNYSTASI
                     EWRPLDSNHHIFTTEQTITVKYIGDDINYIEGSEDEKKLKLDMTNVDVDGDGIPDINI
                     DTDGDGRPDINIDTSGDWKPDINIDTDNTGEWKPSTEGGNGDGIWKPDKNIDTNGDGN
                     PDTDYNRPAIDTDNDGVDDYWKPDKNVDTGSGGYDTGNPNLNKPDPDNGGNSKPDPD"
BASE COUNT        11832 a         3462 c         4588 g        10986 t
ORIGIN      
        1 tataatatgt aatatttttg ttttgaaatt tataaattag tattactggt tagagttagt
       61 ttagtattaa gtatattcga agtagttttt tagctatttt catacattta tattacttaa
      121 ttatatatag cctaactaac ttaatatatc agtgaaatat tgactaaaat gcctaaatat
      181 gttatcatac aagttagtca aataatttgg caacattaaa tatttagtaa atttctaata
      241 tttatggaag aaatttctag caaggaaggt gagatttata tggctggtaa aaaaatatta
      301 gcaacaaaca aaagagcaag acatgaatat tttatagaag aaacttatga atgtggaatt
      361 gaattaaaag gaacagaagt aaaatcaata agacaaggca aagttaacct aagtgatgga
      421 tttgcatctg tagataatag cgaagtattt ttaaaacaag ttcatataag tccatatgag
      481 caaggaaata tattcaatgt tgattcttta agagttagaa aattattact tcataagcat
      541 gaaataagaa agcttattgg agcaactact ataaaggggt attcacttat accacttagt
      601 ttgtatctaa aaaacggtaa agttaaagta gagattgcct tagcaaaagg taaaaaacta
      661 tatgataaac gtcaagatat ggctaagaaa gatgcacaaa gacgtataga aagagaaatg
      721 acaggtaagt attaaactag ataaaactgt attttttaga ataaaattct ttattatcta
      781 gaacataaca ttgattttta ttcttaaaag tattatatta tatatacatt aaaaatttaa
      841 taaaaatggt gataaagttt gcgaaaagtc tactggacta taaactactc aagggggcgt
      901 aaaggtttcg acgtgggttt ggaacttgag gctgcatgtc gtgttactct gggtcacgta
      961 aaaactgggg aactttaaaa taaacgcaga cgataatttc gcgatagcag cctagttgct
     1021 gctcgtccct cttagtcctc ctgccgacta agactggacg tcattatgca gggaactact
     1081 ttaggggtgt ctcgacttga agtagattaa ttgggactgg ctaagcatag agcctgccac
     1141 ttggcgctat gtgaggtgag atattagtga agttggctaa gcatgtagat gcagcaagga
     1201 aaagatttgc ggacaggggt tcgactcccc tcgtctccac caattttgaa aaaagaatga
     1261 tgaaatactt ggaaatacta gtctttattg actagtattt tttattttgg agataaaatc
     1321 caccaaccgt accccaacca cagaaaatga ggtatttttg agagtatatg ggggtgcatt
     1381 tgagtgtatg aaaacattta cttatcatta cattagagag gataggaatt taatacatac
     1441 tttagggagc tttatcagaa gccttaaata tgaactcaga agaagtttat aaaatactta
     1501 aacataacac tgatatttca aataccttgt tatgaatcat tacattttta aagtaaaagt
     1561 tacatagtag aagatttaat agaaccactt aaataaaagg aagtgttatg atgattgcat
     1621 atcatagttc ttattgtata gcaaaaactt ctgattctat attctaaaga ggttctttaa
     1681 attttgataa aagattttat gtgattagta taaaaacgca gatgattaac aggatggaat
     1741 gatttaagag aagaggtaaa aaggtgtatg tagatagttg ttttttagaa ttgatataaa
     1801 atcaatttaa ttatttaata tttatttttg taaaattaaa agaactgtag atacgtttaa
     1861 ataaaccact atttcacacg cgttttctaa aaatagtggt taaaatgtta ttttttatat
     1921 ttatttacaa ctttagtaat ttgattatga tgaaaaggtt tgttaggatt caatttttta
     1981 gttaatctat tagctatttc tctaagacta atgttacaat ctaacataga taatatttca
     2041 gtaatatttt cttctagtaa ttttatagaa ctttttggag gtattaaatt ttgttttgat
     2101 atatgttctt tatatacttg cccaatcaca tttaaatcaa agggttttcc tattaaatta
     2161 gaacctaatt tatgtgatat ttgtcttaat gaataattat aattatgttt aaggtcaata
     2221 agagtatcta tatgtttatt tagtaattct ctttgtgtag gaggtttttc tttaagttct
     2281 tctcgacgag tatatttgta atttttataa atacttatta ctgttttatg gtcataaggt
     2341 ttatctcttt tcaccaaaat agcaatttcc ctaccaattt tactaaatga gtaattttcc
     2401 acatctctta attgtacaat cttttttatg atttcttgat tatacaaata ataatctcgg
     2461 ttagttcttc tacgctgaac tttatcattc atattatctt tttggtcgcc agttcttaag
     2521 tgacttgctc taatacataa tggattatca caattgtgta gaatatattt gccactactt
     2581 gaagtattag tataagtgtc ataagagtac ctacttgctt ttatttgttt gttattttta
     2641 tggactacag gacagtattt ttcacttccc caatttgctt caatacagac ttctttaggg
     2701 aaaaaaattt caagtttatg taatgcctct actttttctg cattagttaa ataaatataa
     2761 ttccatacac tacctttttt aatatagagt aatagctcta atggtataga taaaaattta
     2821 gctatttctt ctattgaata attaaattca gagttattca tattatttaa taaatatttt
     2881 gttaaatata ctgattcttt agttaaaact atctcattaa tttctggtct atcattgaaa
     2941 tatttatcaa gaatattttc agatacttta cgttcttcta tatgacttgg attaacacaa
     3001 catcgattgt aacaagtatg atgtgcttgg tatccatttc taattggcct ttgtagtctc
     3061 tcttctagta ctattcttgc agctcttaaa gtaccttctt tatttgaatt aatttgacca
     3121 taaccatcac ggtctctata tcctggataa ggaatgcatt caatcaattt tatcacctca
     3181 tttattaata ttaaattaat ttgtatcatt attttgattt tgtaattaac tatatgaaat
     3241 catagtattt ttatgtgttt gatttttaca atgaaaatat tttatctaac ttttctacag
     3301 cttcaacttt cttatcttcc ataacttgag tatatatatt taaagttatt gatatatcat
     3361 aatgacccat taaaacttgt acagctttag gagggacatt attctcaaaa agtctagtcg
     3421 cataagtttt cctaagacca tgaaacttta taggctctat atctagactg tttaatatag
     3481 attttagatt ccttaaaggt cttttatcat ctatagggac acctaattta ttgcaaaata
     3541 cataattatc atttctatat aattctccag cctttaatat atctgtattt tgacttactt
     3601 tatgttcttt caatttattt aagatattct ttggaatagg tacagttctg taagaatttg
     3661 atgtctttgg ctcttgctct aatactttaa gctctctatc tccattttta tctataaaat
     3721 atgttctttg aagcgttctt ttaactgtta aattagaatt cttaaaatta atgtcaaacc
     3781 atttaagtcc taataattct cctaatctaa gtccagtacc aagagcaagt aaaaataata
     3841 cctctaattt atgtccatct atagctttta taaaactctt ttgttgttca agagtcaata
     3901 tttcaatctt attttccttt ttctcaactg gtatatttac catagtacaa taattacgtt
     3961 gtataagacc ttgtttttca gcttctgata agcaggtttt cagtttagtg tttatttgcc
     4021 ttatagtagg tatactttta ttggaatcaa gcaatctatt gtaatatttt tgtatgtgag
     4081 atactcttaa gtcatttaat ttaacattga ctaaatcagt atctttaata taattgcgat
     4141 agatgctttc atatctctca aatgacttag gttttaaatc ttttattcta tatttaaata
     4201 accaattgta aaaccaatgc tctaaagtta ttttatcatc tgaaatatca gagcttaaat
     4261 aatattgttt tttataagca tctaatttat ctttaacttc tttttgagtc ttaccataaa
     4321 attcttttct tattggtttc ccatcttcat tgtaaccaat cattatacgg gaacgccaac
     4381 catctttata ttttccgata gagccttctc cattagctat tttagttgcc atttttaaac
     4441 agctccttat atgatttata gttatattca tcaaagaatg taatacattt ctctaataag
     4501 aattttataa cttcatcacc ttctagtgtt tcatagaagt ttagcattaa tgtgttgtat
     4561 tcttgtttat gtttagctgg tattgataga actcctatat cattacttat aagtattagg
     4621 tttgaggtaa gtctagcagt tcttttgttg ccatcataga agaattgaca ataggacaac
     4681 cataaattta ttattatagc cttttctaag gggttagtta ttttatttat gatatttatg
     4741 tcatttacaa ataaatcatt taatagagtg ggttctatgc actcatattg ggtagtacca
     4801 gctataccta tattaccatt tctgaaatct ccaacgatta gagcttcatc ttttgcaact
     4861 attttatgta tagagcaaat tgtatcttta tttaaagata atttttcttt gttacttaat
     4921 tttattacat aatcccatga tgattttata tttagtattt gattttggtc acttaattta
     4981 tgtccaccta ctgttatacc atcaagtaat gtttgtactt ctgggaatgt gaaggggtta
     5041 ttttctaggt tacccatatc atatacaaat tcacttatca ttcttctaat gtatgttaaa
     5101 gtatattttt tatctccatg aggtagatta gtagggaatt tatgtgtgta ttttggtata
     5161 tatgatttat tcatgatttt agctcctttc atatctaatt tttatttatt aactatgaat
     5221 gtataaaagt taataggtaa acctatattt tgaaaatatg caatactaat attcttcatc
     5281 ctcatcttca ataagaccat tagagttttc ttgtataaaa ttttcaacaa gaccatttat
     5341 cacccaattt agatttttgg agaagtcttt gaagtcagag aagtttaggt taattggttt
     5401 tattgtatct gcattatctg taatttcaaa ctttttttat agtctgtttt tatatcataa
     5461 ccataatttt ctaatatgtg aattactaaa tccaactctt tatcaaatac ttttaaatta
     5521 atattattat ttgttaaagt atctaaatca ttttcttcaa caatgagttt atttatagca
     5581 attgataaag cagtagctat ttttcttatc atatctaaac taggtattct ttgattttgc
     5641 tcatatttag ctatagcatg aactgaacaa ccaatcttgt tggttagttc attccttgat
     5701 atatttatcg atttcctata ttgtttaatc ttttctccaa ttgtattatt tattataatt
     5761 ccaccttaaa tatatcatca aacaatgatt atatttttac acatataaag gagttatttt
     5821 ctagattatc tatgttatat actaacttac tcataattct tttaatgtat atcagagtat
     5881 attttttatc tccatgaaat aaattagtag ggcatttata tgtgtatttt agcatatatg
     5941 atttattcat aattgtaact ccattcatag ttttttatca ttgctttaga tagtattgat
     6001 attattttat attttagtta gtagtttttt tatttcttta agtgtatttt caagcttttc
     6061 atttttttcc tttaattcgt tattttcttg taataattta aagtaatcat tatttttaat
     6121 agtaatattt tctttttgag atattaattt ttttagtcga atattacttc cattatctgt
     6181 tgagtcacta aagtaatcat agattgtttc tatattttct tctgatagac caatatctaa
     6241 taattcatca attgattgtt ttgtaagaac atcattttta ataatttctt ttatgtcatc
     6301 aggatgtaat gaaaaatcta attcagtatt agatatacaa tctgaaagta tccaattata
     6361 aacttgattt tcatttagtt ctaatttttc accaagttta taatattggt ctttatcaga
     6421 ccaagcacct agcaataaac ttgaggtaat tctaatatca tcatcttcca taagatttga
     6481 aatagcattt aaaaattcat caaaagaata gtattcttct gggaataaag actgtaaaaa
     6541 gtataaaaca tcttcattag taattacttc attttcaata tcaaaataaa agatagtctt
     6601 ttcaattttc aaagctttag cgagttttga taaggtatct atattaggta ttcttttatc
     6661 attttcataa tttattagag catttcttga gatgtcacta atttcagcaa gttgaatctg
     6721 tgttagttct ttttgttttc ttatcttttt taagtttttt ccaatttgca atattatcac
     6781 ctcgtataaa gtatatccta aaagtacaca aatgagaaca gaagaataat atatttttat
     6841 tgggtatata catatatgga cattataatt aaaatataaa gtttacaaat gtaaactaga
     6901 aaaggtgata atactcttat atatcagtta gaaaatgata taaataaaac taatcagaaa
     6961 ttaataaaaa aggattcaag tataacggct atatcagaga gagcatttga ataatataaa
     7021 tgatgaaata aatgaaggtg ctaagactag aataaagttc ctagagaata ttataggagg
     7081 tttatatggt ggtgaactaa ctccaatagc agttaaaagt agaagaggaa aaatagcatt
     7141 agctttacaa atacttagaa atgtaatact tcaaggtaag aaagtatttt ttataagtag
     7201 agaaatgagt aatatacaga ttttgtttag aaatatagca tcactaactg gaatatcaat
     7261 tgtaaaaatg aagaataaaa acttagatga tgatgaaata gtcaaatata tacaagtttt
     7321 aagtataata aatcaagaaa ataatcttta tataaatgac tctgtaaata caatatcagg
     7381 gataaagcga gaaataaaga gtattaaatc tagtttagta ataattgatt atttgcaaat
     7441 tttggattat gaagctaaag aaataggaga aactaaattt gctgacttat cagagcaagt
     7501 aaaaaatatt actttaaaat ttaatatatc agttgttcaa tttgctcaat taagtacata
     7561 tgcatagaga tattttagaa aaagataagt tatgtaggat attgcaaagt gattagagag
     7621 attaataaat tgttagaaaa ggttttacta gatgggaata aaaaatgtgt attagtagag
     7681 tgggtattag atagtatcat tttagaagtt atatatagca tgtttatatt aaagtagtaa
     7741 atatattaat ctatgtactt gttttttaag taaaataata gcataaaata aaggttttta
     7801 aaagtatatg tctaatttta taaataaaca tattatataa ggacctgaat aaatatttga
     7861 agagataaaa ttatattaaa cttaatatca aaatgcttaa agatgtctta ttttaatatt
     7921 ccttatcata gttagaactt atagaattct atatatcata atagtggtaa atttaaatat
     7981 gtatagaaga ttaaataata atatatgttt attataaaaa ataatacaaa ttaatgtgta
     8041 taaaaagatt tactaaataa gtataatcaa gtaaaaatta aatatgaaga tattaattat
     8101 actagaaaga taatagtata agcaattaag gatgcaatat taaattctta ataaacttat
     8161 atctagggag gatatcaaat gggaaagatt gaacctaatc aagaggaccg tatatatgaa
     8221 gatttatacc agggaaatag cgctgaaggt aaggtatgtg aatggataga agaagctatt
     8281 aatgatgatt gctatgtagg acaacataga tttaagattg agacaagaga atgtgatatt
     8341 gctatggtta taccaaatag aggcatatta ataatagaag taaagggcta tactgtagaa
     8401 atgattgatc atatgtcaag taattttatt atacatgtaa agaaagagta tgaaaatgaa
     8461 agatttaaaa ctggtgaaag gcatccagca gaacaagcaa atgattatgt atttacaatg
     8521 atgagagatt tttcaggttt tttaaaaagg aataacatat gtttaccaat atgtaaaata
     8581 ggacgaatgg cagcaatgcc taatatgaca gataaagagt atgaggaatt atacttggat
     8641 tattgttatt caacaaaact tgtaatcaca aaagattggt ttaagaataa aaatatattt
     8701 taccatcgtt ttataaatgc acttaatata atttttaatt ctataagcag tgaagtagat
     8761 ttcgatgata gttattataa tattgcgaga aggtatattc ttttaggtga acgtaaaaaa
     8821 tatgtagatc tatgtaaaga gcaacttaag cgagaagaag aattgggtat tgattttata
     8881 atagacaata ctaatgaaga agtagatcaa ctttgcaaat cgaatgaagt taatgatgaa
     8941 gaaatggaat tgataaaatt ttcttctgtt ttacaagaag aattaacgga atcacataaa
     9001 ctatctaaaa ttattcctta ttctaaatta cgtatagtta agacaggttg tgaaatagaa
     9061 ccacttttgg agatttgttg taatgaacgt aaagaaggaa taaagcagtt tctaatatta
     9121 gttaatttta caagagatga gaaagaaaaa atattgttag aatatgaaaa aagattttta
     9181 aataagtata aggaaaatga actgttattt ttattcaata tgtattttat agatttatct
     9241 aatgatgata caagcattga caatctattt agtaatcatg ataatattga aattattaat
     9301 ggagagagaa tagaagagat tgtcaaaata aaacctgaca attttattgt acaagaattt
     9361 acaccaaaag atctgttaga tcaagctttg tggaatatat tatgtattgc agataatttt
     9421 acttcattta attttgatca gtatatagtt gaacattcac ctcttcgtca aaacattgtt
     9481 gtaactgcaa gtgctggtac aggaaagaca tatactatgg ttgatcgagt ttcatttgtt
     9541 gcacatatgg agattattta tagaaactct aaggaatcta ttagtgatct aatctctatg
     9601 ataacattta ctaataattc aacagatgag atgaaggaac gattaatgaa acattttatg
     9661 cagtactttg agttaacaca taataaagta tatatggatt tattagaaca attaggtaga
     9721 atgaaaatta aaacaataga ttcatttaca aaatatattt tatctaaatt tgctcattta
     9781 ttaggtcttt ctaatagttt ctcattaaaa agcggaaagt ttgaattaga gaatatttta
     9841 agaaaatata ttaatgatga gataactaag gaaattatag atgatttcca taatataaat
     9901 atttatgaaa ttgctaatca tattcttgct ttgcgttcgt ttcttattaa tcgaaagatt
     9961 caatttgata aaataaaaca tgcttctatt gtgggacctg atgtagggaa gggaactatt
    10021 cgtatgaaaa attttataga gtctgtactt atttctacaa atagtgaata tgatagtttt
    10081 aattgtagtc aaaactttat ttcgatgaat gaattagtta ttcaattaga gaaggtcaaa
    10141 aataaattga taaaaactag ttgtgttaat aatactaaag aaaattatga aaaatacttg
    10201 tttatagatg aatttcaaga tacagataat aaacagatac aattaataag attttttgcg
    10261 gactatttca atattgcact ttttgttgtt ggagatgaaa aacagtgtat ttatggattc
    10321 agaggagcag aaagaacttc atttttagaa cttacatgtg tagatactaa ctttcaacaa
    10381 agaaattgga tatcatgttt tctaagaaaa aattatagaa cagaggaacc cttagtaaaa
    10441 aaaataaatg aagtgttttc taaaatgcca aatgattttt tcccttatca aaataaagat
    10501 aaattagtag ctcaaaaagg aattggaaga atttattcag ggtgttatga acaatttaaa
    10561 tatagtgaaa ataacttaat agaactcgta gataattgtg ttaaaagaat gaaaaaaaat
    10621 aatgaagatg gacaaattgc tattttaaca agaaataatt atgaggttga tcaaatacgt
    10681 gctttgtttg gagagaataa agaatatgaa attaaatttg ataatggtgg attattttat
    10741 aatactgatg ctgttattga tttttataaa ttagttgagt ttttgatgga tacagaagat
    10801 ggtgctaaac gatatagtat tttagaaact ccttatagtg atttcagaat taaagaatcg
    10861 aaaataaagc tatatcaagc ttatgaaaaa atggatgttg aaacctttga aataattagg
    10921 tctggaaata atcatgtatc tttacgaaaa tattatgatg tattatataa ttatgggaaa
    10981 aaacatccaa atttaaagaa tagcccaagt ttaaagatcc ttcgaatgat tgttaatgaa
    11041 attaaaccat gggaacacta tgtaccagaa agatataaaa ctgttgattt taatgatata
    11101 tgtaaccaga ataagctcat tgaagctaga aatgagtatc gtcaaaattt atttcagtta
    11161 tttcaaaaat taatagatga taataaaaca gactatttaa cacttaataa gatacatcaa
    11221 attttaacta ttggtatttt tgcaatgcaa gatattgata ttgatttgcc taaaaataat
    11281 ttttttggag aaaaaataag tgtattatgt acaacagtac ataaatctaa aggtcttcag
    11341 tatcatacag taatcatgcc atttacaatg aatgatataa cagagtcaag aggatcaaca
    11401 caatttattt atagagaaga tacaaatgag atctatatgc aattaaaaga agctgatgga
    11461 aagtgtctaa tttatgaatc aaccaatttt gattgtgaaa ataataagaa aaatgaaact
    11521 atacaatcag aagaattaag aattttatat gttgcattaa cacgttcaaa aaaatttttt
    11581 tactttatgg tggatgaaga aagatttgaa aaaaataata cttctaaaaa aaattgttgg
    11641 gcacattatc taatgtaagg tggaggaaaa taatatgaaa atctatacat ataaaaattc
    11701 tgtacaattg aaagatgcaa tcttctggaa tgaaatagaa ggagcacctc atttttgttc
    11761 ctctgaagta ctagcaatag gaatgagaaa attttatggt agaaatactt ttccatgcat
    11821 ttctactata gatttattga taaaagaact ttatccaaat tggcttaaat ctcatagtga
    11881 tatagagcga tataaagata tatctaaatt aattaatgaa cttaatgatt caagtacaga
    11941 gggtttaaga caagcttttg taaaaaataa aaaatctata ctagattctt gtaaatattt
    12001 gattgaaact gaagatttgc tcttaaaaga ttattacaat aagaacatat ttaataaatt
    12061 ttcagcaatt aatgatattc aagaagtttt taaagaaaag atactgaaaa gacttttaga
    12121 acaaatatac attgatggaa acaaaaatta ttggaaacct gagtggatag atacattatg
    12181 ggttaaatca aagttaagtg aagtaattca taaatgtgtg ataaaagaaa ttagtgatat
    12241 tgttaagaat acagaagaaa agagtttaaa tcataattat gatgaaggtc atatttttga
    12301 aatatttgat gaactgtttg accagcatgg attatttaat atatcagata agactttaga
    12361 atattggaaa tttaattcta aagatgattt gcttgataaa attggatact catcaaaaga
    12421 actagagtat gttcgtaatc tagctactac tgaatgtaag tcatataaga ctatagtaat
    12481 tcatggtgtc tatcatttaa atccaattca cttaagattg ttaagagatt tagaaagaga
    12541 tcataatgta attgtattaa attgttataa taaagaattc aatcatattt atgaattttg
    12601 gaatgatata tatgatcatc taattaaaat atttcaaatt ccaaagaata atataaaaat
    12661 tgatagtcat gattctgcta atcacagaga agttggtagt atatttgctg aagttgtaaa
    12721 tggtgtaatc aataaacaaa gtaatttctt taagataagc agaaatgaat ttggcccaga
    12781 cttaaattta aattctaagg atattgatga actttttaat cataatagta gtcaggatat
    12841 tagatatata ttaaataaaa gtgaagctat tattcaaaac tatgaggatg aagatgaaag
    12901 agagtatcag aagatactta tagatacatc aaaagaactt caaaaagaac tatgtcatag
    12961 aagtaagatt ttaataaaat atgattctac aatgcaattt gtcaataaag tgtgtaatat
    13021 atttgatgaa acaaagaata aaaaagggat acgttcagtc ggaaggatga aggagcaatt
    13081 ttatggttct aaaggtacag aaatgaataa aatatttcaa gtattttatc cagatgaatt
    13141 taaagttaag ccttttctta gttatccaat tggacaattt atttatgcaa ttcataatat
    13201 gtgggatttg aagaatcata aacttatatt aaatagtaga gatttagctg aatgtttaaa
    13261 tttagatgta tggcatgata ttcatccatt agaggtattt gaaagtttac gtttttatat
    13321 tggtattgat aaagagccta atggtatgaa tgtaaaagat tttattgatc gaataaaaaa
    13381 actaatatat tttaaagaaa gaaacgaaaa taaaatgaag aatttagata atcttagtta
    13441 tcttaattta actatagacc aatataatag atttattcaa gtaattgaaa acattaacga
    13501 aattgcaaat aagatatttt gtaataaatc acaaacaagt aaaaagcatt ttatggattt
    13561 actagaaata ttaaatgatg aaaaagcttg gaaacctcta ttagaagaag aaaaaagatt
    13621 aatggatgaa attaaaaatc aaattattca tattgatgat gaaactaata agactgactt
    13681 aaacacaata aaggatacta tggcatatta tttagatagc aaagaaggta ctgatattaa
    13741 ttggttggtg cgtgattttg agcaattaga aggcgatatt ctttcagaag cagcaaatta
    13801 taaaaataat actttgagac aaaaatgcta ccatttaact atgttgtcaa atgaaaatat
    13861 gattaattgt gatatagata atttaccatg gccattaagt gatgatttta ttatatcaaa
    13921 aaatatttct tcctttatac atacaatttg tataaactat gcaaaatata aacgttgtct
    13981 attgtttcaa ggattatatt atttgataaa taatccaatt atttcactta agttaagtta
    14041 tattgaaaat caaggagagt ataaacatac accatactat attttaaaca tgtttatgaa
    14101 tataggaaag gattttgatc aatcaaattg cagaaatatt gaaagttgca cttctccaat
    14161 taataaagag ccaaaaaaac gttttaaaat agataaaaaa tggcataaag atgctataga
    14221 gtcatttagt tgttgcccat ataagtttat gtatggatat gttattaatg atgctgcaaa
    14281 acattataaa gatgagttac aagtgaagat gtatttagga gaaattataa aatattatat
    14341 tagtattgcg tggaaaaaaa ttttacaata ccataaaaaa ctattattgg atcaaaagtt
    14401 taatttactc aaaaaatgga ctgctggtga aagactagat tgtcttgaaa aatctttacc
    14461 agagacacta gaacctattt atggtaatta tttcatcaaa tctgagatta ataaaattat
    14521 agtagataac ttagaatatt taaaaaataa aagaattgat aataaaagag tatattttac
    14581 agaggagtgt aaaatatatg aagttgatag agaactatat cattgttgga taggtaaaat
    14641 atcaaatcat aatttatatg taacaaataa aaataaaata attaatatta gaaatcgtct
    14701 aaacttacta aatgcaaatg aatatataaa tgactatatt cttggaatta atgatggatg
    14761 gtattttaaa aaagataata ttgtagttga gggaggatat aaagtatctg aacatgcttg
    14821 tagatattgc tcatataata aaatatgttg ttatcagtat aggataaaac ctatacactt
    14881 gctacattca aaagaagatt taattgatta ataattagat aaactttaag aactatatca
    14941 ataggataga cggttttatt tattttctat cctattgatt aaatctaaaa gttttagttt
    15001 tttagttaca tattgaatca tattatagat tgttatcttc ttgtattatt tgagtgataa
    15061 aatgttctaa attactggaa taattgtatc tgtttttaag cataattgca cccctatcta
    15121 tatgaagctt tacttggtta ggaaaatatt cattatcact taaatgtcta cctatatgct
    15181 gttcaaataa agttttaaat aaagtatcat attgattggt tatggtttgt ctattaagct
    15241 caagaccatt attatcaatg ttctcataac tttcaattga ttcactataa cttaacgaca
    15301 ttgaaatagc cagtttgcaa agagcaaatg gtttcaaatt cattctagat cctaactctt
    15361 caaatatttc ttttgtttgt gttgatgttt taagtttaaa tctcataatt acacctcaaa
    15421 aaagtatcct ttattttgta tagttttttt gtttttgcta tcatattcaa gcaagtattc
    15481 tctacttaac ttaggtttta ttattttata taatttctca tctatttcag tattagtaga
    15541 tagtattata atttgatgac ttattgtaga aaaatattca ctagtaatgc tatttctatg
    15601 agtatcatct attctagcat aaggagtgtc tataataaag gggatttcta tacctgagga
    15661 tttaagtaaa gcccaatata aacaaagaac atatatttgt ttctcgccac tagagaattc
    15721 atctatgtca actttagttc ttagatttaa aaatgtagat tgagtattat ttcttataac
    15781 attaaatagc tcatatttat cttctacgct atacaaatta aataaatcat caaaaaataa
    15841 ttttcccaac tttttctcca ttccttcaat tcctatgttt tttgctaaat tttcaagctc
    15901 taaagagtta tatattttat ttatatataa agaaatatca aagttgacat taatatctat
    15961 gtggctaata aaattgtctt tttgaattat ctttttaaat atatacataa agttatcctg
    16021 aattagttta attttagttt ctgttaatgt tgttactatt tcgtccaaca taagtataag
    16081 attagtagat atatcaacaa tattattatg ttgaagtaaa tatatgtatt tagccttaga
    16141 tttatccctc ctacttttag tttcagctat ttcaagtttt aatttatcta aagaagtaac
    16201 tagtaaattc tttgatccta ataaagaatc aattttgctt gataaattgg acatatcatt
    16261 aatatatgta tttaaagatt catctttaag gctagtattt aacttgtgtc ttatatcagc
    16321 taattcattt gatatacttc tatgttcttc aaaagaatta attatagaat tattatcaaa
    16381 atttaaaata gtgtttatca gagataataa ttttctactc tcatcatcag aaaggttatg
    16441 gatagattta aagttttctt cataactatc tggctttata tcttctgtta aagcttcaga
    16501 aacagttaaa gctatttcat ctaaggcaga aggcatgatc ttatctgaaa gtagattttt
    16561 tatatactca atatttaatt tatccttaag gcgagaatat agtaggatat cattctctgt
    16621 tttaagttgt ttttctaaat ttgatatctg tttttttaca attaaaaagg gaagtatatc
    16681 attacaaaac tcttttatat tttgattaat tataaatctc tttccttcta attcagcaat
    16741 tctagaatta agggtttctc tttcttctgc taggattcca ccctttttcc tgaattcttt
    16801 ttttacttct aattgttctt gttgtaactt ctcaatttca tttgaaattt tttgtaattc
    16861 ataagaaaaa atttcttctt gagagtttaa agtattgatt tccatctcta aatttaaata
    16921 gctatctttt acaatattaa tttcatctga aacattctta ttagatctat tagttgaaat
    16981 caacactttt tttaaaatat caaatgtatc aaaattacaa agagataata aagattcttt
    17041 taaatgtata tttgaatttt tacctacaaa aaaatcatac aaatgttctc catcaaaaaa
    17101 gaaaaaatca aagattttag gagaaataat agatgtaata taattctcaa aatagttaag
    17161 ttcgtcagca tttaatggtg tagttgaaaa atttttataa actaaaaatg tctcatttaa
    17221 tttttcatcc ttgaaagtcc attgtctaat taaagtatag atattttctt cagtgccttc
    17281 actgatttct atatctactg atactaaagt atcaatctta ctatttatta gagaattatt
    17341 gtttatgtta gatttaactt gagatatata tgaagcgttg aaaccttgat atttataagc
    17401 cataggtcca tatatacata gctttatagc ctcaaatatt gtagatttac cagcaccatt
    17461 tttaccacct atcaatataa tatttttgtc actagtagta tttagattga atgttgtttc
    17521 ttcttcataa gatctgaaat tttttaatac aagtttattt attttcatat tttaactcct
    17581 tgttgccttc ttcttcaatc ttttcaataa tatcttgatg aagccactgt tgatttaata
    17641 ttctttctat ggaagttttt aatttagtat tattactaaa atatttatat ttatttgtat
    17701 ctatgattaa tttattaaat aaatcaatat ttatatcata ctcactacat ttttcagata
    17761 taatatttaa agtaaggtca tcaaatactg gttttttata ttcagaccat ggtaggtttt
    17821 tacctacaac ttccttatat atttttgata atatattacc agttaagtct tcttcgttat
    17881 cccaaatctc atctatagct ttaagttctc ctaattgtat aagttgtaaa tcaggataaa
    17941 atttttgcat ttcaagttga gtttctaaaa gttttcttaa aatagtttgc cttgcttcaa
    18001 atgtaaatgg tccaaacatg attttaccat cttttttaat aacagagcca tttcttttat
    18061 gttttttacg atttttaggt ttatctctct cagaaattag ccaacttctg aattccaaaa
    18121 gtggctttaa ttcatcatga ccagattcaa taaatccgtt taatgatttg tcttctttta
    18181 caacagtaca aatccaacat ccaaacctac tatttccaca gctactttta gcactagctt
    18241 catctgctat aaatgggcat tcatctgagt caccagaacc tttcatatac atctgaaata
    18301 attccatagc atcagttccc catgaggtag atggagatgg tccaaattca ccaccaaaat
    18361 ctatgaaatt atcattttga tgatagagta catcccaaac atctgctgta ctaaaattga
    18421 ctataggggt atacacataa gctaacttat ttttacctct taaggtttca tgtggggtaa
    18481 gaaggtaacc ctctatctct cttttttcga ttctcgattt tctagcagaa ctttcttctt
    18541 tacgaacgcc aagcagtaca ataacatctt tttgttcaag tttttctttt ataaatttat
    18601 ttgatggttt tatcttaagc ctttcagtac accaacgata tttaatagac tttggagtag
    18661 ggtaacctct accaattata ttggcccaaa aactatcatt aagttctggg tatacaatct
    18721 gtgcacttat aggtaaatca tgttcagtag cactttcatt tatcttgtct atattatttt
    18781 ttagataatc aagtattatt ggattttcta taagtgtatc agatgagatt acataaatct
    18841 ctttatgtct tttttctttg ggtagtcttt taagcattct aaatgtaagt tcaactacac
    18901 aagaactatc ttttccagaa ctatatccga ttatccaagg tctatcatca ttaagatata
    18961 cggcctgcat ttcatcatat aaattttcta aattgttgtt atctaggtaa ttaacagcca
    19021 tatattaagt atcctttcta taagagtata gcgaagatct ttacataata ctcctatttt
    19081 aatttatata taattatatc acaatatata tttagagaat agattagttt atatttacat
    19141 aagtacaata aaatataaat ttaattaaat gtagaactgt tatcatttta agataatata
    19201 tttaaaaatt agagaataag aatgtacata cttgaatctc ataaatgtat ataaagatat
    19261 gtatgaataa aaatagcagc tacttagaat agttacacta tttaagattt attatattat
    19321 agattgacta aacaatagat atttattaat gactcaattt ataaacttta aaagttatat
    19381 cccaataata ccccaaccac aaaaataaac aataaaaaat aaccaaaaaa atcagtctaa
    19441 tatcataact aaatagctat atacctacat tcacaaaaac caacaaaaca atcaaataac
    19501 cacttataga ctcccctcgt ctccaccatt gaaatccacg aatacctata tccaattgga
    19561 tataggtatt tttatacatt tttagtttaa atattattga taaatacatt taaaaagttt
    19621 taacctaaag tgaagaatct aaataaaaat aaaatattag gagaggttat cattacaata
    19681 acagcttgtg atgatgaaaa agaaatacaa atcgtaataa aaaatcaagt tgataatata
    19741 ttaaaaaata aaaacaaaga atatcgaatt aaaaaaatat agctcaaaag aagaaccatt
    19801 acaaagttaa ttgagaggat acactactct tagatataaa aatgccagaa ctaaatagta
    19861 tagatatcgc aagaaacata agaaaagtag ataataatat ttataacatc tctaataaat
    19921 tatgtacagg agagatatga agtaagagat tattgatact tattaaagcc aataaatttt
    19981 caagaactag aaaaacacat attaacatat atcaaaaaaa ttgaaaaaaa taaaaataag
    20041 tctaacacat acaaaatcta ctctagcaaa aaaatagata gaagttcaaa aaaagaacat
    20101 gctaatacat acaaaaaata aaacttttga tgctatatgt atcctagaaa aaatagaaaa
    20161 agatttaaat atagaggaac ttgtaagatg tcataaaagt tatataatta acttaaatta
    20221 tgcagaaaat ataaagtcaa atactgcaat attagatagt caagaagaag tacctattag
    20281 tagatataga tataaagata taaaagaggg gtttctaaaa tttattggtg atagaatatg
    20341 ctaaaccata taaataaaat attattaata ttatcattgt ttacaccaat aatgatacta
    20401 aaaagtatat taacttacga taaagataca gataagacta agaaaatatc tttttttact
    20461 gtattattag cttatcttat aactaaaatc attatattat ttaacgttga taagacccat
    20521 aattataata tgaagaaaaa tctatatgat ataatctatt atttgatatt tattatttgg
    20581 gaacttacta taattatttt tataagatag gaattgttaa atatatagtt tcatttttct
    20641 tatctgacgt atatcaccct ttaataaaag atgttatatc tataaattta ttttttgtag
    20701 ttacaagtaa tgtaatatca tcagaggaag ctctattagt gtttagttat gataatgcta
    20761 aagtagatat atactattat cttataataa tagttatata gtagcttgtg ctatatttaa
    20821 atttattaat aaaagattgg gactagataa agataataaa ataaactata tatacttatc
    20881 tgttgcttta ataacaaatt tatttactat attaataatt tatataaata aaaaaatgta
    20941 tcgatttggt gggtattagg aaatatatat agttgggtat attgtgatac ctaggttaat
    21001 actagctagt agcttagtaa ttattatagt gtttataaaa ataattaagg aaaataagtt
    21061 aaaattgcaa aatgaagtaa taaaaaataa gttagatatg cagtattctc attatctaag
    21121 tattcaagaa tcacacgcta aagttaagaa gctttatcat gatataaata atcatatata
    21181 ttgtatagaa aatctcaaat ataaaaaagg aaaattgatg ggtatgtaaa tagtttaaaa
    21241 gattaaatta aagaatttaa atcaatttac aatacaggta atgttatatt ggatataata
    21301 ataaatgaaa aaagtgatgt aagtgaaaaa agaaaaatta aattcatttg tgatatcaat
    21361 ttttccaaag tgaattttat aaaacaaata gatgtatcta atatatttgc aaatacttag
    21421 ataatgcaat agaagcttgc gataagatac atgataaaag tattgataaa tatatacaaa
    21481 taaaaggaac tatctcaaag tcctatttcg taattaaatg tgagaatagt aaaataaatt
    21541 caattagaaa gaataaaagt ttattattaa cagataaaaa agataaactt gtacatggaa
    21601 tagggattta aagcatcaaa tcttctataa aaaaatatag aggagattta tcatttgaag
    21661 ataaaaaaga caaatttata ttgaatattt atataccatt aaatcaaaat tttgatagtt
    21721 gggtcgatta acctaccagt tggggaacat atattgatac taaacatata gggatgttat
    21781 cttttaatag aaaaagatag cgtctttttt ttatgagaaa taacgagttt tcaatatata
    21841 aggaggatta tatgaagata aaaaaattac aataactatg gttatagcta taagcttaac
    21901 actaggttta ataacaggat gcacaaataa gatttcagat acaaatgaaa aaatatatac
    21961 tattgaacag atttctagta tcaagaagac ttgtcaaaga aaatatcaga atcaatagaa
    22021 aatagtggtc ttagggtagc tgaaaataaa tcagatggaa gttttgtttt gtctttggga
    22081 aacttggagt atacaaaaga acaacctagc caagttttac attattcaat aactaaggac
    22141 aagaaggata cgaaggaaat attatcaatt caatgtgtta aagatttttc ttataatgaa
    22201 aagctgtcag aagatgataa attcataatg gccatttata acatatagat cattgattca
    22261 tatagaaata agtgagaaag aattttttag aaaaattgaa gaagtatttg ataaaggtga
    22321 agaaaatgta gaggttgata atttgggaga tataaaaatt caagttaaga aatttgatga
    22381 taaaactaag cctttagaat taaaacttat taaagaattt aaattgaagt aggaagattc
    22441 actatgagaa aatacaaagc tattttatta actttaatta taagcattat agccataata
    22501 ggatttatta tatacaacaa ctattttaga aaatggaatg aagctgaaaa atatatagat
    22561 aaatatatga catatcaagg agtttcaagt gatgatatag agcgtattac aaaagaaaag
    22621 tatacaaaag agaattagga tgggatactt tataaatcat tttacaaaaa ctatccaggt
    22681 tataaatact aatattttta taatggtgat tattatgcac tacatgtaaa taaggtgata
    22741 ctgcaagttt atcatgagga agatggtagt aagcttcaaa aaataatgaa gaattaaaag
    22801 atttaaaata tccaccaatc tacttaacag atgagttgga taaataattt atagtaaaat
    22861 aggaggatta tatggggatt tacttaaaaa tgtcactagc atatttaaag aaaaataaac
    22921 ttagaacatt acttttaata ataggagtta tgttaggtgt tatgttgata tttggaccta
    22981 gtgttataaa agattcacaa aatgaaaaca atgtagtagc aatacatgaa ctttacagtg
    23041 gataccatgt agagtttagt gatttgacac ttgatgatgc taaaaaatta gaaactgatg
    23101 aaaaagtatc aaagggtaat tcggtacaaa atctaggacg tatttcagat aaaaaaggaa
    23161 actcatttat attaacttca tcaaacgaag agtatctaaa aagtagatac aacaaaataa
    23221 tagaaggtag actacctaaa aacaacaatg aaatagtatt agagaaaaaa gcactagaag
    23281 caatgaattt aagtgaagga gtaggatcta cattaaattt aacaataaaa aagaactata
    23341 aagatactaa cggaagtaat caattatttt ctataaataa agaatttaaa atagtaggag
    23401 ttatggaaaa accaaaaggg tactatgatg tggtttggca atacgaagca gtaacttatg
    23461 gcaatgatga aacaaacaac attataccta atgatgcgat tagttataat agtatattaa
    23521 gttttaaaag tggatggaga aatattgaag gtgaatgtga ttatcttatg aaaaaatata
    23581 agttaggaca aaaaagcttt ctaccaaatg tacctcttgt aagggaactt cgttatgtag
    23641 aagatgataa gagtgatccg aatgttttta aaagaaatgt tttaataact acagtatcta
    23701 taattttcat atttaatatt ttcaatatta cactaaatca atcagtaaaa gaaatgggac
    23761 tgtttagact gatgggtgca aagaaaagaa acgtaaggtg tatgataatc tatcaagcat
    23821 taattataac aataataggt atactacttg ggttagtagc tggggttaca tattcatata
    23881 taggaattag taattataac gaagttttat acagtgaagc tggtcttaac cctaaattat
    23941 atataaataa tgaaatagtt ataaaagcta tattggttgg aataatttct gtttttatat
    24001 cttgtattat accaactttt aaaatcggca agatatcacc tattgaatca ataataaata
    24061 cagacaaaat taaaaatcac agaagtagac ttggaataga cagactagta agcaaaatat
    24121 ttggatttta tggatttatg ggacttaaaa atattggaag aaataaggtt agagctgcta
    24181 tatctatgtt gtctattgct ttaggaggat atatattcat tactacattc tcaagtatgc
    24241 aagaagaggt caacagtaaa attgaagata tgcaaaatag atataatata acaatgcaat
    24301 ttggagtaaa tgcagacccg caaatatcaa aatacacgga tagtgatgta gagaatatag
    24361 aaaaaattaa gggtgttaaa agtatacata aaattcaaat aacaaatgga atgtttactt
    24421 ttaataataa ggatataaac aaagaattta caacctataa tggagtagaa aaaaaagaga
    24481 taatggaaga taaattagtt ttaaagcttt atgatgatta tatagatgaa aagttaaatg
    24541 actttgttga agaaggtagc ttagatgata ttaaaaagga cactgatgga tatccaaatg
    24601 tagcagtata taattatttt tatgatatag ttgatgatca tactataaag cctatattca
    24661 aagaattaaa tataggagac ataataactg taaaaattcc tgttgaagaa aataatacaa
    24721 ttgtttataa agagatgaag gtaagagtgg ctgtaatttt aaaggatgaa tggattgcta
    24781 tgggagatgg cgattttatg ccagatctag aaattataac aagtaatatt cactctaaaa
    24841 acataacagg agaacaaaaa tacactcaat taggcataaa tttagaaaat ccatatgatg
    24901 agattgttaa taatgagata cagaaaattt caagaagtat accagggtct ctatttaata
    24961 gtagattaag ttatcatgaa atgtcagaaa gtatatataa aagttacatt aaatcacaaa
    25021 tagcaataat tgcactagtt ttaataatag catcaattaa tattttctgt actataagaa
    25081 caaatctact aattagaaaa aaagaaattt caacgcttag agcattaggt gttagtctta
    25141 aaaatatgaa aaaaatgctt atatatgaag cattagcata tgcagttttt agctttataa
    25201 tagctatgat tccatcattt ataaatctag ttaaatttac aaattggaat aatgatgcgt
    25261 atataaacta tggaatagag aattttatgt cttttacatt cccaattaag gaatctttac
    25321 tattctttgc tatatctgta tttgtatgtt taatagcagt agttgtaagt aatagagatt
    25381 ttgaaagtat gaatattatt gaaggtataa aagagaatga ataatttggg aggtaaatgt
    25441 atgaagatgt taaaagttat agatattaaa aaaatatatg gaaaaggaga aaatgaaata
    25501 aaggctgttg atggaattac tttagagata gaaccccata aatttagtgc aataattgga
    25561 caaagtggtt ctggaaaaag cacattactt cactgtatgg cagggcttga taaaccaact
    25621 ttaggtaatg tatttatgga taatttagat ttatatactt taagtgatga aaagctatct
    25681 aatcttagaa gtaaagaatt tgggtttata ttccaaaact ataatctaat acctgttatc
    25741 aatgtttatg ataatatagt tcttcctatt ttaattgcta aaggaaagat agataataat
    25801 tatattaatg atttaataac taagttagga ttagaaagtc agattaataa atttcctaat
    25861 gaattatcag gtggtcaaca acaaagagtt gcaatagcaa gatcacttgc caataagcca
    25921 tcaataattt ttgcagatga acctactgga aatttagaca gtaaaacaac taatgaggtg
    25981 atgaatttac taaagtattg tgtaaatgaa tacaagcaga cgttggttat gataactcat
    26041 aatgatgaaa tagctaagat ggctgattgt ataataacta ttagtgatgg taaagtcata
    26101 taaaatgtat tgtataaagg tttaatcgtg ggtattattc ttgtgattct tctccactat
    26161 ttaaatccac gaaataagga ctgtcgaatg agtaatttta aattgctgtg cgacagttct
    26221 ttttttactt gcttttcatt aatttatatt tatgcaaaat ttgagcttga aaacggtcat
    26281 aagaaataaa ggtataaaaa taccatttta aaatagaata atttacaaag tgtaagatta
    26341 aaaaatagtt ttgagaggat gaatatacat actacattta ttaatgatta tcttatttgt
    26401 gaaacttaga aatactatag gctaacacta caggtataaa ctctgaaaga atatcttgat
    26461 tgcctctgat tagaattctt ttaaagttca tactatgttt tatttgggtg aaagctcctt
    26521 atgcctgaat acttctattc attctaagtt cacatccttg tgtaccagtg attctttcta
    26581 aattatctta atgccaaaat cttgttcgca tttcaaaata aagtcaggta gctacttcaa
    26641 cattttagtt atatttcttc aatagtttgt ctccaaacaa aggtacatct attagcaaca
    26701 gatttaattt tatttatatc aataaataat atatactttg aaacttcatt aatatcacca
    26761 agataattta taagttaaac tattatatat tatcttcact aactacatcc tccatagttt
    26821 tacactttct taattcagct tggtaatcta aatctgtaat aattatttct ctttgatttt
    26881 tcatttcttt gcctacaaaa gtttaatatg aatattattc tatacttacc aattttacgt
    26941 tcaaaaaaga ctgtagataa gtctgcattt acacaaacct acttataggt ctcttttttg
    27001 aaattaattt agcatgaact atagtaagag catctttaaa ttcatattta caagtataca
    27061 aagttataat tttatctgaa atatctacct ttatatcaga tttgtgtact gatttttagg
    27121 ttatataatt caaagaatat ttaaactcat cattattatt aaagtgtata cttaaataat
    27181 ctctgttaat taagtcagca gtatatactg aaaaaatttc ataagtataa gtttgtactt
    27241 tataatttat ttctactaaa ttattttctt tgaaaaatac ttcatcagta tagttttcta
    27301 gctgaccaaa catagtttta tttttcatat aatgaccata gactattaaa ctcttatcat
    27361 tttcaaaatt atttctataa tccatgaaaa tactacctaa aggaagataa tttttataaa
    27421 aatcatgagt taggtagaaa tcattgttat atccttgtac tacaggatag tctatattta
    27481 cgttgtttat tttaagccag aatctataat cattattttt atcataaagt tcttgatgtt
    27541 tgctattatt gatagtgttt tctctgagtt ccgtatatac ttcatcagct ttttatattc
    27601 agataatttt atgtaaatcg aaaggctaga gaaagttagc gtaataatgc aaataatatt
    27661 tattaatatt tttactagtt ttttcaatta attacccctt gtattattat ataaaagatt
    27721 aaataaattt tatataatta aaatttttat tgtagttatt tagcaaataa tgaatactta
    27781 taatatataa ggttgaaaaa aactgtatat tcattgacaa atataagttt taagtatata
    27841 ttaaaaatta ttagagtgta tataaggatg tatacagtgt atattaagaa ttattagagt
    27901 gtatataagg atgtatacag tgtatattaa aaattattaa ggggaggggg aatttatgca
    27961 acaaaaatgt aaaaagaaag cactatcaat gattttaagt atctcaatgg gacttggatc
    28021 agtagcatca tttaatgcgt caaatacttt cgcagatact atagaagaaa gtactaatgc
    28081 aggaaatgca gaaggagata ctaatgcagg aaatgcagaa ggggatgcta atgcaggaaa
    28141 tgcaggaggg gatgctaatg caggaaatgc aggaggagat actaatgcag gaaatgcaga
    28201 aggagatgct aatgcaggaa atgcaggagg agatgctaat gcaggaaatg cagaaggaga
    28261 tgctaatgca ggaaatgcag aagaagattc taatgcagga aatgcagaag aagattctaa
    28321 tgcaggaaat gcagaaggag atatgaatgc attagttgtg gaagaagcca ctgcagaaga
    28381 tcctacatct gtaggagact ttaaaattag tggtggagaa ataaatgtcg attttaaatt
    28441 tgcaagtggc gttttaacta ttcttagtgg aaaacaaatg acaattcaaa ataataatcc
    28501 aaatactcca acaacacata ggattgttat acctaaagat gtaaaagctg aattaatatt
    28561 tgatggagta aatattaaaa ctgcatctaa tagtccattt actttaacac cagataaaga
    28621 tggtggtgca tatgcacatg ttatattaca agatggtagt gaaaacaagc tagagtcagg
    28681 tgatgtatat tatccaggta tgagagcagg aaaaggtact actctaatta ttgatgattc
    28741 tgttgtaaat agagatattg aaggcgagtt tatagttcct gagggtggaa aaattcctag
    28801 agatgtaact ctagaaaatg gagacaagtt aaaaaaagga gatcgcctta cactactaga
    28861 tagtaataat agaggaagtt taaaagttgt tggaaattat tattctgcag gtattggcgg
    28921 tggaaatact gaaagtggag gaaatattat tattaatggt ggtgctataa ctgctatagg
    28981 tcaagaatcg agtcgtaata caggatatgg agctggaata ggtggaggcg gtaatggtag
    29041 tggtggagat atcacaatca atggtggtac tataactgct aaaggtgcat accatggagc
    29101 tggaataggt ggaggatact atacaacaac aaagaatgca ttaagtccct cagtagtaga
    29161 tcctagcaca ggttctggtt atagtgggaa tattacaatt aatggtggac tttcctattc
    29221 atatggaggt gcacatggta gtgcatttgg ggatggatgt gttaatccag gaacaaatag
    29281 aggatatcgt atacttgtaa ctggaggaac gattttacct tatatgacag gagtgggaga
    29341 ttggattttt gacctaagtg ctacaacggg agatgttata gtaacaggtg gttcattaaa
    29401 agcaacaaca ttcaaaagtt taggtggagc agttgcatac ggtgatttag aaaagaaaac
    29461 aaaagttttt atgaataaaa tatctctaac gtatttaggg caagataaag ttagtactac
    29521 actagttgat gattttaaaa tgctaattga tggaaaaatt tatccttatg gagcacctag
    29581 ttatacagat gctcaaggga ttctttactt atggttctct gataaattta ctggatctga
    29641 agtatctgtt aatttagttg ttatagataa aattactgga gaagttctaa aaccagatga
    29701 tttttatatt aaagatatag gttcaggttc tcaattttta aagcaatatg aagaatttac
    29761 tattgatgat actccaccat atttgattat taaaagatat gatggattac catttgaaga
    29821 agacgtagaa aaatcatttt tagattggct attaaaagat ggtggtattc caataactac
    29881 tcctaaaggt gaaaaactca cagataaaaa atttatgact attagttctc aacgtttaaa
    29941 tgaggaaacg atggaaccag atataaattt aggaagtgat gatcttacaa aacaagttga
    30001 tgctgggaaa tatcaattaa gcattacatc aacacagttt tcgagtatat atccttttaa
    30061 ggatgcttat tgggggcata gagcatacta taaggcagaa attattcctg ctgatacaga
    30121 aacttcatta gttgtagaag agtctaaagc taaaactgat gtttttaaac caacagatac
    30181 gtttacatta aatgttacta tttcaccaga taagaaagaa ggaccagatt gtgcctctcc
    30241 aagaggttac gtacaattct atattaatgg aaaggaatat aaagatccag tagaattaaa
    30301 aactcataat aagggtagtg agagtcataa ttatagtact gcatctattg aatggagacc
    30361 tttagatagc aatcatcata tttttactac tgaacaaact attactgtaa aatatattgg
    30421 agatgatata aattacattg aaggtagtga ggatgaaaag aagttaaagt tagatatgac
    30481 aaatgtagat gtagatgggg atggaatacc ggatataaat atagacactg atggtgatgg
    30541 aaggccagat atcaatatag atacgagtgg tgattggaag ccagatatta acatagatac
    30601 tgataataca ggtgaatgga agcctagtac agaaggtgga aatggagatg gtatttggaa
    30661 acctgataaa aatatagata ccaatggaga tggaaaccct gatacagatt ataatcgtcc
    30721 agcaatagat acagataatg atggagtaga tgattattgg aagcctgata aaaatgtaga
    30781 tactggctca ggaggttatg atacaggtaa tccaaatcta aataagccag atccagataa
    30841 tggaggaaat agcaagccgg atccagat
//
LOCUS       DAMJXI010000040        30843 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.042, whole genome shotgun sequence.
ACCESSION   DAMJXI010000040 DAMJXI010000000
VERSION     DAMJXI010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30843
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.042"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            274..3822
                     /locus_tag="PC465_002406"
     CDS             274..3822
                     /locus_tag="PC465_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2649692.1"
                     /translation="MMNRLKPRILGISILFIIIIILTCGAVFKFKFKLDNKLKETTHT
                     YLSEFTEHNIINLKTRLSGQFDMLESIANFIGNLNNINDEMVIDLMDSDVKRSSLIRM
                     TISTLDGECYSNDGITHNVQDRDYFKKAKNGEKNISEPLKSIVNNKEIIVLSTPVYKS
                     GKIVGVLSGIYDSKKLNELLGLSAFDEKADVFVAKKNGDIVAQKTNKNRKTLSCIFQL
                     FDKDNCDEDDCLKTIKENMKNDKSGYFNYNLDNEKFMLNYQPLGVNDWYVFSVVPNKI
                     VSIQSENISYDVYIFALEILLVILIFIIYIACIINNNTKIIINEKEKFKVLTDNILGG
                     VKTCLKDEYMTMTYVSQGFLELTGYSCEDLNKIFKNRFKDMIYKDDLDKFNCIILNQL
                     EKQDKIEVEYRIVRKDGSIIWILERSKSINDNKGSECIQGVLTDITELKKIQEELDSK
                     RFEIQAINDSIVGGIVITEINDDFDSIYLNEGYLNMIGYTRKQLEDELNNKLIKLIFK
                     DDRTELINSINKQLKLSDTFASEQRVEKRDGTIIWILLKGRKMIYDNGKSVLCCVIVD
                     ITSAKLLEQELKKSEERHEIILKQTQNIIIEWDIEKDKMNISPNWYNKFKYDPITENA
                     TKNIIKSVDIYHDDMDKFISLIKLTSQGSEYEECEIRLRTRDTIYAWFSIKATTLFDN
                     NGKPYKVVGSLTDIDESKREAEKLKERAEKDPLTDLYNKKASQSLIEEYITLDKKRKG
                     ALMIIDIDDFKGINDNLGHLYGDAVLSEIANDLINLFRATDIVGRIGGDEFIVFIKDI
                     SETRDIINKAEELVKTFERSFLGKGRNYKISLSVGIAKFPQDGMDYMTLFRNADMALY
                     SAKGKGKNCYTLYDKKIDKVQYITNTRNAGDSDNVEMSFKEHITNYIFDILYESSDIE
                     VAVNLILSIVGKHFNVSRMYIFENSDDNRVCKNTFEWCNEGVTSEINNLKNICYKDLG
                     NYLLNFNADGLFYCNDIENLGSDVKKVLKPQGIRSILQCKILEGNEFRGFIGFDECSY
                     NRMWTNDEVNTLTFISKTLSMFLLKMRIQSKLEESLTIQKSVMDNMDIWAYVVDRNTY
                     ELLFINKKMLESAPNTHVGDLCYKAIWNNQDKPCKKCPMIYLKDGDDTYKSFMHNKKF
                     EVQANITTTTLKWFDGKDACLIFGSEITSIEAEENT"
     gene            4007..5941
                     /locus_tag="PC465_002407"
     CDS             4007..5941
                     /locus_tag="PC465_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HDF2649693.1"
                     /translation="MENKFLPISKQDMIDRGWEELDFVLVTGDAYVDHHSFGTAIISR
                     VLESAGYKVGIIAQPDWRTTDDFMKLGKPRLAFLVNAGNMDSMVNHYSVSKKHREKDM
                     YSPGGKMGYRPDRATIVYCNKIREAYSDVAIVIGGIEASLRRFAHYDYWSDKVRKSML
                     IDSGADLLVYGMSEKQIVEVANALNDGYDPKYIRHIDGTCYISDTLEEIYDKYILIPS
                     YKEICEDKMKYVEAFKIQYDEQDPFRGNIIVQPHGSKYLVQNKPEKPLSREELDEVYG
                     LPYQKTYHPVYEKFGGIPAIEEVKFSIVSSRGCFGSCSFCAITFHQGRAVQSRSEKSI
                     IDEAIGITNLDDFKGYIHDVGGPTANFRRPACKKQITKGACKNRQCLSPSPCKNLDAD
                     HSEYLHLLRAVRKLPKIKKVFVRSGIRYDYVMADKNNKFLRELIEHHVSGQLKVAPEH
                     ISEEVLKYMQKPAGKTYDKFRQKFFAINEELGKKQYLIPYLMSSHPGSTLNSAIELAE
                     YLRDTHYQPEQVQDFYPTPGTLSTTMFYTGIDPLTMKPVYVPKSKRDKAMQRALLQYR
                     APRNYDLVYSALVEAGREDLIGFGHRCLIKPKNEKPYFNRNNSKKNVSKGTNKNKKTN
                     TNNRSNKNQQKSSTKKKKKH"
     gene            6047..7042
                     /locus_tag="PC465_002408"
     CDS             6047..7042
                     /locus_tag="PC465_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2649694.1"
                     /translation="MKKYISIILLVVLTMVVLVGCSPGKDNPKNKELSVVKQVKVAVP
                     DGLPAVAIAKLANENPEIKEGYETVYSIEKTPEAISTRVMKKDADIAIVPSNMAAIAY
                     NKTSSYNIVGTVGMGSLYLVSTENIKDYSDLVGKEVGCTGKGLTPDITIKSLLLQKDI
                     NYSDIKFNYVNSASELVPLLATGKVKTGIVPEPALSALMSKNPDIKIIKSLNDSWKEV
                     SGSKDGYPQSTLIVKSEFLRDNKDFVDSFVGQLSNSIDWANKNPEELGAYSEKIKIST
                     ESKIIGKSLERANLKYIPVKDMIKDYKNYYEKLANFDDKTLGGKVPDEAIYFVEK"
     gene            7014..7799
                     /locus_tag="PC465_002409"
     CDS             7014..7799
                     /locus_tag="PC465_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDF2649695.1"
                     /translation="MKQYTLLRNKKNKEQFIDKMEVTLSCVILLFLWQIIALKIDNDI
                     FLPTVGQVFNSIKEIMLNSSFYIDILYSMGRCFFSFLLAMIFAIILSIVSYLNRFFRN
                     LLKPINALTRSIPTMILVVLALIWFEKDSTPFIVGFTIVFPILYDNVLGAILNIDKNL
                     LEMANVYKIRFIDKVLKIYLPAIKFQIISILVSTFSLSLKVAIAGEVYSQPTYGIGTM
                     IQTEKINFNTSGIFAWIIIVLLISAILQIAQKFLARRAFLWKR"
     gene            7787..8485
                     /locus_tag="PC465_002410"
     CDS             7787..8485
                     /locus_tag="PC465_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2649696.1"
                     /translation="MEKIKLSIENINKRYDSRIIFRDFNIDFYVNEVNCILGKSGCGK
                     TTLLNIISGIIKNDTNNLNIKENLNRVGNKLEASYIFQDDRLIDWLTVEENIKIVVNK
                     YYNKTQLNKICDEYLELVGISDYKKFYPQMLSGGIRQRVNIARAFIYPSKNIIMDEPF
                     KSIDAKNTQLIMDNFRNILRKEKRTVLFVTHNIEEALFLADRIFILGDSPIRIKKILK
                     NSKELEKNEVLKLI"
     gene            8608..9081
                     /gene="ybaK"
                     /locus_tag="PC465_002411"
     CDS             8608..9081
                     /gene="ybaK"
                     /locus_tag="PC465_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HDF2649697.1"
                     /translation="MVKTNAMRILDSNKIDYKVMSYEVKSEHVDGVEVAHDIGRDVNE
                     VYKTLVTQGVSKNIYVYVIPVHENLDLKKAAKVAKEKSVEMIHVKDINKLTGYIRGGC
                     SPIGMKKLYKTFVNESAKNLDTIIVSAGKIGYQIELSPFDLQRLIKVEFVDVIKK"
     gene            9278..10117
                     /locus_tag="PC465_002412"
     CDS             9278..10117
                     /locus_tag="PC465_002412"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HDF2649698.1"
                     /translation="MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVG
                     KNILNILVENAEIAKEKNIPICQDTGMAVFFVEIGQEVLIEGDTLTDAINEGVRQGYE
                     EGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
                     DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDEN
                     IAKLESELLTAINKLGIGPQGLGGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKK
                     VVI"
     gene            10130..10678
                     /locus_tag="PC465_002413"
     CDS             10130..10678
                     /locus_tag="PC465_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-containing hydro-lyase"
                     /protein_id="HDF2649699.1"
                     /translation="MIKITTPVNEIDIAKLNCGDTISLSGILYTARDAAHKRLIDCIN
                     KGEELPFDVYGQGIYYVGPTPTKPGDVIGAAGPTTSYRMDDLTIPLLERGLRLMIGKG
                     KRSDEVIEGMQKYGAVYLAAIGGAGAYISNSIKSCEIIAYEDLGAEAIRKIVVEDLKL
                     TVAIDSYGNNIYEQGRAIYECK"
     gene            10744..11925
                     /locus_tag="PC465_002414"
     CDS             10744..11925
                     /locus_tag="PC465_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HDF2649700.1"
                     /translation="MSKDYAKLALEMHEINKGKVSVESKVEVKTKDDLSTAYTPGVAE
                     PCLKIHENQDDVYRYTSKGNLVAVVSDGSAVLGLGNIGAEASIPVMEGKAILFKQFAD
                     VDAFPICLKTNDVDEIVKSVELMEPVFGGINLEDISSPRCFEIEERLKKSLSIPVFHD
                     DQHGTAIIVAAAIINSIKLIENKKIEDLEIVINGAGAAGIAIAKILLNMNVKNIILCD
                     RSGALEASIENLNYVQKEMLKVTNIRNEKGPLKDIIKGKDVFIGVSGPGAVTKEMVES
                     MSEKPIILAMANPTPEIMPEEAKLGGAFIMGTGRSDFPNQVNNVLAFPGIFRGALDVK
                     AKEINEEMKIAAAYAIANTISDEEICPEYILPDVFNKNVVKNVAKAVKEAAIKTKVNR
                     I"
     gene            12220..12606
                     /locus_tag="PC465_002415"
     CDS             12220..12606
                     /locus_tag="PC465_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009248914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2649701.1"
                     /translation="MEYKVNDQELNASMFIPFVNRIWPGDYNMDKTQTALSKTLNITA
                     YDDKVLVGCLRVLSDGYYFGTITELLVLPEYQKQGIGSKLFQLAKENTPTMLYFGAQP
                     GVEEFYEKNGCQRSLQSYIIKKKDSY"
     gene            12756..13019
                     /locus_tag="PC465_002416"
     CDS             12756..13019
                     /locus_tag="PC465_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2649702.1"
                     /translation="MEETKFCQCCAMPMGQTDELYGTNKDGSKSTDYCSYCFKDGEFT
                     ADISMEEMIEVCIPHMLQSNKDMTEDEARTMMNNFFPTLKRWK"
     gene            complement(13148..13990)
                     /locus_tag="PC465_002417"
     CDS             complement(13148..13990)
                     /locus_tag="PC465_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF2649703.1"
                     /translation="MINIGDFNKLTVKRKTEFGYFLDGQTNNTKDDILLHNRLIGKNE
                     INIGDEVNAFIFKDSDDRTAATLIPPLAKVGDVAHLKVVDNTDIGTFIDMGLPKDILV
                     PFKAKTYPLFRDEKYLFYIYLDKSKRIAATTDIDSYLLTDHTYNVGDIVTGVVYGFQT
                     NNSAMICVDNKYAGVILHNEYFTELKTGDVLENLHVIKIYEDGKLGLSPRGNRKDELD
                     TLENKILSYLEGSDGYMRFNDKSDPKDISILFNSSKKNFKRALGVLMKKGLIYQDEEG
                     TYLK"
     gene            14285..15019
                     /locus_tag="PC465_002418"
     CDS             14285..15019
                     /locus_tag="PC465_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2649704.1"
                     /translation="MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNI
                     QNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIK
                     TDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
                     KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYN
                     REGSPIEYTISIFRTDKYQYEIVLSE"
     gene            15029..16162
                     /gene="nagA"
                     /locus_tag="PC465_002419"
     CDS             15029..16162
                     /gene="nagA"
                     /locus_tag="PC465_002419"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDF2649705.1"
                     /translation="MKCLINGKIILKNQILENKVLVFDEKIIDIADSVPKDCEVIDAD
                     GKYISPGLIDIHIHGNMGKDTMDSTDESIETISKSIMRHGVTSFLPTTMTMDKEHVYD
                     ALEVIKKAQNRKLEGAKVLGAHLEGPFINENYKGAQNEKFIINSKYEFIKEYKDVIKV
                     ITYAPEKDIDFDFTREIKRCTDIVLSIGHSNANYDQAKEAINLGVTNVTHMFNAMTGL
                     NHRDPGVVGAALTTNVYSELIADTIHINKDLFQFILNNKGKERLILITDSIEAGGLED
                     GNYSLGGQKVIVKGNEARLENGALAGSVLSLNKMVFNFLDNTNLKVNEAINLASLNPA
                     TSLGINDKKGSLEIGKDADIAVFDENLDCKMTLCLGEVVYKNI"
     gene            16261..17010
                     /gene="nagB"
                     /locus_tag="PC465_002420"
     CDS             16261..17010
                     /gene="nagB"
                     /locus_tag="PC465_002420"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012425552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HDF2649706.1"
                     /translation="MRVLVCKDYDGMSKKAAEMIAAQIVLKPNSILGLATGSTPVGMY
                     RDLVKKYNDNIVDFSDVMSFNLDEYYKLPISNDQSYDYFMKENLFNHVNIKPENTHLP
                     NGMADDIEKECMNYEASIDAAGGIDVQVLGIGRNAHIGFNEPDTKFAKRTHVVELTES
                     TIEANARFFKSREDVPKKAVSMGIGSILKSKKILLLASGEEKADAVYNTVYGDITPEV
                     PGSILQLHKDTIVIVDEAAASKLNPKDYKLV"
     gene            17185..17457
                     /locus_tag="PC465_002421"
     CDS             17185..17457
                     /locus_tag="PC465_002421"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649707.1"
                     /translation="MLKIIMFSGILSSIIKLPIIGILPTGNIKKNTGISDSKKDGKQR
                     RSNLGISIYQLPSFLYSLINNSVPSNKPIPPEEIKLIKMYLLKSCI"
     gene            18117..18821
                     /locus_tag="PC465_002422"
     CDS             18117..18821
                     /locus_tag="PC465_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2649708.1"
                     /translation="MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNI
                     KECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTK
                     PFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNI
                     DLTPNEYNLLTYLFENIDRAVSRDELLNKIWGYDIEVETRAADDTVKRLRKKILNTNI
                     LIETVWGFGFRLKEKS"
     gene            18823..20310
                     /locus_tag="PC465_002423"
     CDS             18823..20310
                     /locus_tag="PC465_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2649709.1"
                     /translation="MKNGNDKNRIGKIKSKFKLKFSKKNISIKTRILLSILCLIIIVF
                     MIILVSFNVFLDTYIKTTANEELTKSTEIVEHMDSNFRPIKPPQDDGKLPPKVLSNFM
                     RNVQDKVRMAETQSDADAMVVDSKYNLIFPTREDDFLKNVDEMELIRECIQNEKLDLN
                     SDANTRISTRNKDYYISTVKITSIYGEQDKYLILFIDISKTLNLAQKINIVLISVMCF
                     AGILAIFTAVILSEKIAKPIKELCEFAKKMGQGDFKRTYFDFSDKELVELSTVMNKSA
                     EYLDKYDNEQKIFFQNASHELRTPLMSIKGYAEAIKYNVIDSKHASDIILEESDRLSD
                     MVEDLLYISKIDNITKDFELVECDLREVLSNCGARQNVRAINKGIKFIYEFDEEMVLF
                     ECDEKNISKAFMNLIENALRYAKSEIKIVCKYNQKNIVVIIEDDGIGIKKEDLPHVFE
                     RFYKGVGGNHGIGLSIVKSIVNKHGGRIYVENGKKGAKFTILFKL"
     gene            20515..22128
                     /locus_tag="PC465_002424"
     CDS             20515..22128
                     /locus_tag="PC465_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2649710.1"
                     /translation="MKEQLIFNITNLVTVVFEAFVIHMFLSDFLGQKEGYIKVVRYAK
                     LGFIICLGFCNLITLNPKITMPLIFILIFSTSFLYKGNLKTRLFTTVLLSIFFILSEI
                     VVTSIFVLFVKEGFEIMLENNSIRVLATILSKIVFLLTCKIICLFKKDVHLDMPIKYW
                     LPLFLIPIFSLFLSVSIFDVSKFFSLESLKFLSLISSVGILYINFIVFYLFKFIIDKT
                     KLSMKYELLEKEIIHKEELRLSNECYKIIVEQTDSVVFEWNIKENKSFVSQAWTEKFG
                     YNNACKNIFKEIKDKDLVHSEDKAIFEGFLESIKKKNMHNQAVYRLKKSNGEYIWCRT
                     SITSIYNDENELLRVVGVIVDVDSDIKKYEELRTRAESDSLTNIYNKGTFEKLVEETI
                     VMNTGDKKDALFIIDLDDFKEINDNFGHPFGDFVLKTFADKIQTSFGSKDLVGRIGGD
                     EFVVYMQDYVTEVNLHKKAKELNRVLSDNYTDLSFSFDASVSIGIARYPQDGTSFFEL
                     FKNADRALYSIKASGKNSYCLFEEELYVQ"
     gene            complement(22491..23321)
                     /locus_tag="PC465_002425"
     CDS             complement(22491..23321)
                     /locus_tag="PC465_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2649711.1"
                     /translation="MSQVSKNYFTTGEFAKICGINKKTLFHYDDIGLFSPELKKENGY
                     RYYSYHQLSIFGIISSLREVKMPLKEIKAYIDKRTPNLLIELLEKKTIDIKNEIEKLN
                     NIQALMESTISFTKNACNIDANTITLKEHEEEYLVKTPVTYKEQFLGDEEENFLYECI
                     NFMDNYELSDYGTIGSIIKGEDIINKDFESYSYLFTKVNKEYKKYPVSIKPKGLYVTA
                     YHKGSYETIYKTYEKLLNFFNQNNLRIGDFVYEEYLLYDISVRDSNEYLTQISAEVKM
                     "
     gene            23394..25121
                     /locus_tag="PC465_002426"
     CDS             23394..25121
                     /locus_tag="PC465_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2649712.1"
                     /translation="MKKLIHFLKPYRVLIVVVLIFTFLQTLGTLYIPTLTANIVNNGV
                     VKGDIDYIVKTGLMMMIVAGITALSAVLVCKVSANLSSGFCRDIREAVFIKSQDLSIN
                     DFNNIGTASMITRSTSDITLIGQSVFMFIQLVLPAPIITVSGLFLAYSIDKAMTIIIV
                     VVMFLFMLSAFLVGKKLIKLFKMMQIKMDNMNRVLREVVTGVRVIRAFNRSRFEKKRF
                     DRTAIDYSETAISINKIFAVLMPIVMLIMNLGIVSIIWFGGMRVSNGNMEIGHIMALV
                     EYCILILFYLIMGVMVFMYIPRAGACADRVNQILDIEPEIVDGNGHKDTVSERGHLVF
                     KNVTFSYAQSEEPVLNNITFEAKSGEVTAIIGSTGSGKSTIANIIPRFFEIQSGEISI
                     NGQDIKKIPQKELRDKIGFVPQKAFLFSGTIEENIRYGKEDASIEEVKHAASIAQADE
                     FISDMEDKYDSFVAQGGNNLSGGQKQRISIARALVRKPEVYVFDDSFSALDFKTDKRL
                     RKALKNEIKDSSAIIIAQRISTIMDANQIIVLNDGKIVGIGKHKDLLENCEVYKQIAD
                     SQLSKEELA"
     gene            25158..27020
                     /locus_tag="PC465_002427"
     CDS             25158..27020
                     /locus_tag="PC465_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2649713.1"
                     /translation="MSEKRIDEQDIEVLSFEDGMSAEKAKDAKKTTKRLLKYMAKQKF
                     KILIIFISVLISSALTVLAPMVMGKAIDQLFNGIKTAVQTGTKFSVNFSTMGGIVSIL
                     LGLYLISAVFIYIQQYIMSGVAQNLVLSMRKDLSDKLNKLPLKYYDSHKKGETLSIVT
                     NDLEKVADSLQEGLMQLITAVVTVVGSIVMMISISVPLTIVSAITLLVSLGITVVIAR
                     KSQERFSENQKALGELNSNIEEIFTGQIVVKAFSKEKDTIRNFKILNQNLYNASRKAQ
                     FSSYAISPIIRFINLIGYVIIAVVGGIFASTGAMTLGSIQAFIQYVNQASEPTTEISY
                     IVNMLQAAIASAERVFTVMDEVEEIKDEESSKVISMPKGKVQFEHVKFGYSDDFILMK
                     DININLNAGDKIAIVGPTGAGKTTLVNLLMRFYEIQGGRITIDGVNIKDLKRGELRTM
                     FGMVLQDTWLFNGSIKENIAYSKSDATMDEIVRAAKSARVDHFIRTLPQGYDTILTED
                     ASNLSQGQKQLLTIARAILSDPSVLILDEATSSVDTRTEVEIQKAMNNLMKGRTSFVI
                     AHRLSTIRDADLILVMKEGTIIEQGSHKELIEKKGFYEELYNSQFTSEYDEDVV"
     gene            27353..28042
                     /locus_tag="PC465_002428"
     CDS             27353..28042
                     /locus_tag="PC465_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HDF2649714.1"
                     /translation="MNKKLNYRFEMKHKITEADVLALKSRLYPIMKKDENASKDGKYL
                     IRSLYFDTPEDKALLDKLNGVAIREKFRIRFYNNDCSYIRLEKKIKHYNMTSKLSTNL
                     TKKEVINILNNDIEFLKESTNCLLREFYLKLKCERLEAKSIVDYNREAFIYPVGNVRV
                     TIDSDIKTSVNSVDLFNKDLPTVSVIDDNMTVLEVKYDEFIPDFIKDLIQINKTTSTA
                     VSKYASSRLYI"
     gene            28147..28833
                     /locus_tag="PC465_002429"
     CDS             28147..28833
                     /locus_tag="PC465_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HDF2649715.1"
                     /translation="MILIMTFNDIFKSSFIENVSGFSFVDSALALGSAFLVGLFIYMV
                     YKKTYMGIMYSRPFNVSLVALTMLTTFVILAVTSNVVLSLGMVGALSIVRFRTAIKDP
                     MDLVFLFWSLGSGIVLGAGLIPLAVMGSIIMGLILIFFSNKTISETPYILMVNCNNED
                     SEDIATDKIKKVFTKYQIKSKSVTPEKGIELVFEVRMKDGETSLINDLSQVDGVTNAV
                     LVSYNGDYVA"
     gene            28850..30757
                     /locus_tag="PC465_002430"
     CDS             28850..30757
                     /locus_tag="PC465_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HDF2649716.1"
                     /translation="MKDKKFTLLISIMIIFLCAVVGVYSTSSNKSVDLYSDVYIEKYF
                     NRDKVMEVNIEIDESDLKDMNENAIKEEFKVAKVTVDGDTYGNVGIRTKGNSSLISVA
                     NSDSDRYSYKINFDKYNTSQSMEGLTQLNLNNCYSDPSYMREFLTYSICEEMGLATPE
                     FAYAKVSINGEYHGLYLAVEGLKESYLENNFGNVTGDLYKSDEGSSLQYKGDDPESYS
                     NLIVESDKKTADWSKITKLLKSLDTGEDIEKYLDVDSVLKNIAINTALLNLDSYQGSF
                     AHNYYLYEQDGVFSMLPWDFNMSFGGFSGFGGGSQSIAIDEPTTGNLEDRPLISSLLK
                     NETYKTKYHKYLEEIVTKYLDSDYLENMTTKLHDMIASYVKEDPTAFYTYEEFEKNIT
                     SSIEDSSDNKGFGNKGFDNNNSNNSDSNNNSNSENKRSGNQSDEKEVNAELTSSVVKA
                     NTDNETKNKTTNDSESKNNTDKDKSGNDNNQKLEGPMGKGGKSIPGVLEVAEDMSKTI
                     KSQLSGETSSTKQNSGDESSSGIKGSEKFDEDMSGMPEPPEGMDGKMPPGMGNMDKGD
                     MNGKNGNMNMDRNQDNPREAGGFGNRGGGSVSKTTTYFKLILGGASMIIMSIMLVGVS
                     RVKRRRFIKSK"
BASE COUNT        12192 a         3221 c         5395 g        10035 t
ORIGIN      
        1 taattaatta gaaaaggaat gaataataat gaatatatta cattattact ttttgataaa
       61 tcaaaaataa agttataatt tttaatatta attaagaatg atgaaatatg aataaagatt
      121 ttacaaataa atcttaagct atcttattta attctaatac aggaagaagg taaatgtata
      181 ttgaaaaaat catagaaata gaagtaaaca atttaaataa atacaaaggt ttgcaaaaga
      241 agtaatataa ttatatacaa tgaggatgtg agtatgatga acagactaaa gccaagaatt
      301 ttaggtatta gtatcttgtt tattattata attattttaa catgtggagc tgttttcaag
      361 tttaaattta aattagataa taaattaaaa gaaaccacac atacatattt gtctgagttt
      421 acagaacaca atataattaa tctcaagaca agacttagtg gtcaatttga catgcttgaa
      481 tctattgcta acttcatagg aaacttgaat aatataaatg atgaaatggt gattgattta
      541 atggattctg atgtaaagcg aagttcttta attagaatga ctatctctac attagatggg
      601 gaatgttatt ctaatgatgg aattacccat aatgttcaag atagagatta ttttaaaaaa
      661 gctaaaaatg gagaaaagaa tatatcagag cctttaaaat ctattgttaa taataaagaa
      721 ataatagttt tatctacccc agtttataaa agtgggaaaa tagttggtgt tttaagtgga
      781 atttatgatt caaaaaagtt aaatgagtta ttaggattat ctgcatttga tgaaaaagca
      841 gatgtttttg ttgcaaagaa aaatggagat atagttgctc aaaaaacaaa taaaaataga
      901 aagacgctat catgtatatt tcagcttttt gacaaagata actgtgatga agatgattgt
      961 ctaaaaacta taaaagaaaa tatgaaaaat gataagtctg gatattttaa ttataactta
     1021 gataatgaaa aatttatgtt aaactatcag ccacttggag ttaatgattg gtatgttttt
     1081 tctgttgtgc caaataaaat agtatctatt cagtcagaga atatatctta tgatgtatat
     1141 atttttgcat tagaaatact actagttata ttgattttta taatatatat agcatgtatt
     1201 ataaataata acaccaaaat tattataaat gaaaaagaaa aatttaaagt actcactgat
     1261 aatatattag gaggggttaa aacctgttta aaagatgaat atatgactat gacatatgta
     1321 agtcaggggt ttttagagct tacaggttac tcttgtgaag atttaaataa aatatttaaa
     1381 aatagattta aagacatgat ttataaagat gatttagaca agtttaattg tattattcta
     1441 aatcaattag aaaaacaaga taaaattgaa gttgaatata gaattgtaag aaaagatgga
     1501 agtataattt ggattttgga gagaagtaag tctataaatg ataataaagg aagtgagtgt
     1561 attcagggag ttttaactga tataacagaa cttaagaaaa tacaagaaga attagattca
     1621 aaaagatttg aaatacaggc tatcaatgat agtattgttg gtggaatagt gataactgag
     1681 ataaatgatg attttgatag tatatattta aatgaaggtt atttaaatat gattggatat
     1741 acacgcaaac aactggaaga tgagctaaat aataaattaa tcaaacttat ttttaaagat
     1801 gatagaacag aattaattaa tagtataaac aaacaactca aattaagtga tacatttgca
     1861 tctgaacaaa gagttgaaaa aagggatggc actattatat ggattttatt aaaaggaaga
     1921 aagatgattt atgataatgg aaaatctgta ctttgttgtg ttattgtaga tattacttct
     1981 gctaaattat tagagcaaga acttaaaaag agtgaagaac gtcatgaaat cattttaaag
     2041 cagacgcaaa atattataat agaatgggat atagaaaaag ataaaatgaa tatatcacct
     2101 aattggtata ataagtttaa atatgaccct ataactgaaa acgcaacaaa aaatataatt
     2161 aaatcagtag atatatatca tgatgatatg gataagttta tttcattaat taaacttact
     2221 tcacaaggta gtgagtatga agagtgtgaa attagactta gaactagaga tactatttac
     2281 gcttggttta gtataaaggc aacaacttta tttgataata atggtaaacc ttataaagta
     2341 gtaggaagtt tgactgatat tgatgaatca aaacgagaag ctgaaaagtt gaaagaaagg
     2401 gcagaaaaag accctcttac agatttgtat aataaaaaag catcacaatc acttatagaa
     2461 gagtacataa cattggataa aaaaagaaaa ggtgctttaa tgattattga tattgatgac
     2521 tttaaaggaa taaatgataa tttaggacat ttatatgggg atgctgtatt aagtgaaatt
     2581 gcaaatgacc taataaatct atttagagca accgatatag taggaagaat tggtggagat
     2641 gagtttattg tatttataaa agatatttct gaaacaagag atattataaa taaagcagaa
     2701 gaattggtaa aaacatttga aaggtctttt ttaggtaaag gacgaaatta taaaatatca
     2761 ttaagtgtag gaattgctaa gtttccacaa gatggtatgg actatatgac actatttaga
     2821 aatgcggata tggctcttta ctcagccaaa gggaagggta agaattgtta tacattgtat
     2881 gataaaaaaa ttgataaagt ccaatatata actaatacaa gaaatgcagg agatagtgat
     2941 aatgtagaga tgtcttttaa agaacatatc acaaattata tatttgatat actatatgaa
     3001 tcaagtgata tagaagtggc agtaaattta attctaagta tcgtaggtaa acactttaat
     3061 gtgagtcgca tgtatatatt tgaaaattca gatgataatc gagtatgtaa aaatacattt
     3121 gaatggtgta acgaaggtgt aacctcggaa attaataatc ttaaaaatat ttgttacaag
     3181 gatttaggca actatctttt aaattttaat gcagatgggt tattttattg taatgatatt
     3241 gaaaatttag gtagtgatgt gaaaaaagta cttaagccac aaggcatacg ttcaatatta
     3301 caatgtaaaa ttttagaggg taatgaattt agagggttca taggatttga tgaatgttca
     3361 tataatcgta tgtggactaa tgatgaagtg aacactttga catttatatc taaaacgctc
     3421 agtatgtttt tattaaaaat gcgtattcag agtaagctag aagagtcttt aacaattcaa
     3481 aaatctgtga tggataatat ggatatatgg gcatatgttg ttgacaggaa tacctatgaa
     3541 ttactattta tcaataaaaa aatgcttgag tcagcaccaa acactcatgt aggtgattta
     3601 tgttataaag cgatatggaa taatcaagat aaaccttgta aaaaatgccc tatgatatat
     3661 ttaaaagatg gtgatgatac ttataaatca ttcatgcata ataaaaagtt tgaggtacag
     3721 gcaaatataa ctacaactac tttgaaatgg tttgatggta aagatgcatg tttaatattt
     3781 ggaagtgaaa taactagtat tgaagctgaa gaaaatactt aaaatactgt gttatatata
     3841 tacttaaaat cgcaatttga atttattaga cttaaaatgt ctatataaat catttaagtt
     3901 gtggttttaa gtatttttta tgatataatt aagcgttaag aacaaaatta aaagatactt
     3961 ttgtataaaa aaatatttgt taaatatata ttgagcaggt gataatatgg aaaataagtt
     4021 tttaccaata agcaaacaag atatgataga tagaggatgg gaagaattag attttgttct
     4081 agttacagga gatgcttatg tggaccatca tagttttgga acagcaataa tatctagagt
     4141 tttagaaagt gctgggtata aagttggaat aatagctcaa ccagactgga gaactacaga
     4201 tgattttatg aagctaggaa aacctagact tgcatttcta gttaatgcag gaaatatgga
     4261 ttcaatggtc aatcattatt ctgtaagtaa aaagcataga gaaaaggata tgtattctcc
     4321 aggtgggaaa atgggttata gaccagatag agctactata gtatattgca ataaaataag
     4381 agaagcatac agtgatgttg caatagtaat aggtggaatt gaagcgagct taagaagatt
     4441 tgcacactat gattattgga gtgataaggt tagaaagtct atgttaatag atagtggagc
     4501 agatttatta gtttatggta tgagtgaaaa gcagattgta gaagtagcca atgcacttaa
     4561 tgatggatat gacccaaaat acattagaca tattgatggg acatgctata tttcagatac
     4621 attggaagaa atatatgata aatatatatt aattccatca tataaagaaa tttgtgaaga
     4681 taaaatgaag tatgtagaag cttttaaaat tcaatatgat gagcaagacc catttagagg
     4741 taatataatt gttcaacctc atggaagtaa gtatctggtt caaaataagc cagaaaaacc
     4801 acttagtaga gaagaactag atgaagtata tggattacca tatcagaaga cataccatcc
     4861 tgtgtatgaa aaatttggag gaataccagc tatagaagaa gtaaaattta gtatagtaag
     4921 ttcaagaggc tgttttggta gttgttcatt ttgtgcaata acatttcatc aaggtagagc
     4981 agtgcaaagt agaagtgaaa aatcaattat tgatgaagca ataggaataa caaatttaga
     5041 tgattttaaa gggtatatac atgatgttgg aggtccaaca gctaatttta gaagaccagc
     5101 atgtaaaaaa caaattacta aaggtgcttg taaaaataga caatgcttat ctccatcacc
     5161 atgtaaaaat ttagatgcag accacagtga atacttacat ttacttagag ctgtaagaaa
     5221 attacctaaa ataaaaaagg tgtttgtgcg ttctggaatt agatacgatt atgtaatggc
     5281 agataagaac aataaatttc ttagagagtt gatagagcat catgtaagtg gtcagttaaa
     5341 ggtagcccca gaacatatat cagaagaagt tttaaagtat atgcaaaaac cagcaggaaa
     5401 aacttatgat aaatttagac agaagttttt tgctataaat gaagaattag gtaaaaagca
     5461 atatttgata ccctatttaa tgtctagtca ccctggttct accttaaata gcgctataga
     5521 gttagcagag tatttaagag atactcacta ccaaccagag caggttcagg atttttatcc
     5581 aactccaggg actctatcta caaccatgtt ttatacaggt attgacccgc ttacaatgaa
     5641 gccagtttat gttcctaaat caaaacgtga caaggcgatg caaagggctt tattacaata
     5701 tagagcacct agaaattatg atttggtata ctctgcgtta gttgaagcag gaagagaaga
     5761 cttaattggt tttggacata gatgtcttat aaagccaaaa aatgaaaagc cttattttaa
     5821 tagaaataat tctaaaaaaa atgtatctaa aggaacaaat aaaaacaaaa aaactaatac
     5881 aaataacaga agtaataaaa atcaacaaaa aagttcaact aaaaaaaaga aaaaacatta
     5941 aagtataaat aaaaatactt aaaaaagaag gattattcga taaattaaca gaaattagta
     6001 taaataaata taattatttt aatgacgtta cctttgggag gaagagatga aaaagtatat
     6061 ttctataata ttattagtgg tgttgactat ggttgttttg gtaggatgtt caccaggaaa
     6121 agataaccct aaaaataagg agctatcagt tgtcaaacaa gtaaaagtag ctgttccaga
     6181 tggactacca gcagtggcaa tagctaaact tgcaaatgaa aatccagaga ttaaagaagg
     6241 atatgaaaca gtgtatagca ttgaaaagac acctgaagcg atttccacta gagtgatgaa
     6301 aaaagatgca gatatagcta tagttccttc aaacatggct gcaatagcgt ataataaaac
     6361 ttcatcatat aatattgttg gaactgtagg aatgggttca ctttatttgg tgtcaacaga
     6421 aaatataaaa gattattctg atttagttgg taaagaagtt ggatgtactg gaaaaggact
     6481 tactccagac ataactataa aaagtctttt gttacaaaag gatataaatt attcagatat
     6541 aaaatttaat tatgtaaatt cagcaagtga actggtacca ttattggcta ctggtaaagt
     6601 taaaacaggt attgttccag aacctgcact tagtgctttg atgtctaaaa atccagacat
     6661 aaaaattata aaaagtttaa atgactcatg gaaggaagta agtggttcaa aagatggtta
     6721 tcctcaatct actttaattg taaagtctga atttttaaga gataataaag attttgttga
     6781 ttcttttgta ggtcaattat caaatagtat agattgggca aacaaaaatc ctgaagaatt
     6841 aggtgcatat tctgaaaaaa taaaaatatc tactgaatca aagataatag gaaaatctct
     6901 tgaaagagct aatttaaaat atattccagt taaggacatg attaaagatt ataaaaatta
     6961 ctatgagaaa ttagctaatt ttgatgataa gacattagga ggcaaagtac cagatgaagc
     7021 aatatacttt gttgagaaat aaaaaaaata aagaacaatt tatagataaa atggaggtaa
     7081 cactttcttg tgttatcctc ttatttttat ggcaaattat tgctttaaaa attgataatg
     7141 atattttttt accaacagta ggtcaagtat ttaatagtat aaaagagatt atgctaaatt
     7201 ctagtttcta tatagatata ctttactcta tggggagatg tttttttagt tttttactgg
     7261 ctatgatttt tgctattata ctttcaatag tgtcttattt aaatagattt tttagaaact
     7321 tattaaagcc aatcaatgct ttgacacgtt caataccaac tatgatattg gtagtacttg
     7381 cacttatttg gtttgaaaag gatagtaccc cttttatagt tggatttact atagtttttc
     7441 ctatattgta tgataacgtt ttgggcgcta tattgaatat agacaagaac ttattagaaa
     7501 tggctaatgt gtataaaata aggtttatag ataaggtgtt aaaaatttat ttaccagcca
     7561 taaaatttca aattatatct atactagtat caacattctc tttaagtttg aaagttgcta
     7621 tagcaggaga ggtatatagt caacctacat atggtattgg aactatgata cagactgaaa
     7681 aaattaactt taacacatct ggaatatttg catggataat tattgttctt ttaatatctg
     7741 ctattttaca aatagctcaa aagtttttag caaggagagc ttttttatgg aaaagataaa
     7801 gttgagtatt gaaaatataa ataaaagata tgatagtcgt attatattta gagattttaa
     7861 tattgatttt tatgtaaatg aggtaaattg tatccttgga aaatctggtt gtggaaaaac
     7921 tacactcttg aacataataa gtgggattat taaaaatgac accaacaatc taaatatcaa
     7981 agaaaattta aatagagtag gaaataagct tgaagctagt tacatatttc aagatgatag
     8041 acttatagac tggttaacag tagaagaaaa tataaagata gttgtaaata aatactataa
     8101 taaaactcaa ttaaataaaa tttgtgatga atacttggaa ttggttggaa ttagtgatta
     8161 taaaaaattc tatcctcaga tgcttagtgg aggtattaga caaagagtaa atattgctag
     8221 agcttttata tatccatcaa aaaatattat aatggatgaa ccttttaaat ctattgatgc
     8281 aaagaataca cagcttataa tggataattt cagaaatata ttaagaaaag aaaaaagaac
     8341 tgtgttattt gtaactcata atattgagga agcattgttt ttagcagata ggatatttat
     8401 tttaggagac tctccaatta gaataaaaaa aatattaaaa aattctaagg aattggaaaa
     8461 aaatgaagtt ttgaagttga tatagagtta taataatact gtcgttttaa aatatatttg
     8521 gttaaaatct ataagactat attaaaatag tacagaatat tcaaaactgt gtataatgtt
     8581 cgtattttat aaaaaggaag tgaatgtatg gttaagacta atgctatgag aatattagat
     8641 tcaaataaga ttgattataa agtaatgtct tatgaagtga aaagtgaaca tgtggatggt
     8701 gttgaggtgg cacatgatat aggaagagat gtaaatgaag tgtataagac attagtaact
     8761 caaggagtta gtaagaatat atatgtatat gtaataccag tacatgaaaa cttagactta
     8821 aaaaaggctg caaaagtagc taaagagaaa agtgtagaga tgattcatgt aaaagatata
     8881 aataagctta caggttatat tagaggcgga tgttctccta taggtatgaa aaagctttat
     8941 aaaacttttg taaatgaaag tgcaaagaat ttagatacaa ttattgtgag tgcaggaaaa
     9001 ataggatatc aaatagaact atctccattt gatttacaaa gacttataaa agtagaattt
     9061 gtagatgtaa taaaaaaata agaattacat ataaaatata gagcttatat tcttaataat
     9121 aggtgttgta gtattaataa aatgaataat aattttaaaa taaatattca gttacttatg
     9181 tgtaattggt ataaaaatat tgagaaattt taaaaacaat ggtaaagtgt aagtataatc
     9241 acgaatattt tttataaagt aatggaggga tgttcgcttg agaaaaataa aatctgaaca
     9301 aatcgtcgag caggtaaaaa aactttgtat agaagcgagc ctatatttag gagaagatgt
     9361 tttaagctgt ataaaagaaa aagcgaaaag tgaaaagagt gaagttggaa aaaatatatt
     9421 gaatatatta gttgaaaatg ctgaaatagc taaagaaaaa aatataccaa tatgccaaga
     9481 tactggtatg gctgtatttt ttgttgaaat aggacaagaa gttttaattg aaggagacac
     9541 acttactgat gctataaatg agggagtaag acaagggtat gaagaaggct acttaagaaa
     9601 atctgttgta agtccaatta acagagtaaa tacaaaagat aatacacctg ctgttattca
     9661 ttatgatatg gtaaaaggtg ataaaattaa aatagaattt gcagctaagg gatttggaag
     9721 cgaaaatatg agtaagatga aaatgttaaa gccatcagat ggattggaag gaattaaaaa
     9781 attcataata gatacagttt cagaagctgg acctaaccca tgccctccta tggtaattgg
     9841 agttggtata ggtgggactg tggacaaatg tgctcaaata gctaaaaagg cactttttag
     9901 agaactaggt gaatttaata aggacgaaaa tatagcaaaa cttgaaagtg aactattaac
     9961 agctattaat aaacttggta taggacctca aggcttaggt ggtactacaa cagctttggg
    10021 attaaacata gagacttttc ctacacacat agcaggttta cctgttgttg taaatataaa
    10081 ctgccatgca tcaagacata agaaggtagt aatttaggag gaaaataaaa tgataaaaat
    10141 aactacacct gtaaatgaaa ttgatatagc aaaattaaat tgtggagata caattagttt
    10201 gagtggtata ctttatacag caagagatgc tgctcataaa agattgatag attgtataaa
    10261 taaaggtgaa gaattaccat ttgacgtata tggtcaagga atatattatg taggacctac
    10321 tcctacaaag ccaggagacg ttataggtgc tgcaggtcca acgacgagtt atagaatgga
    10381 tgatttgact atacctcttt tagaaagagg tcttagattg atgataggca agggaaaaag
    10441 aagtgatgag gttatagaag gtatgcaaaa atacggagca gtttatcttg ctgcaatagg
    10501 aggagctgga gcatatattt caaattcaat aaaatcatgt gaaattattg catatgaaga
    10561 tttaggagct gaagctataa gaaagattgt agtagaagac cttaagctta cagtagcaat
    10621 agatagctat ggaaataata tatatgagca aggtcgagca atttatgaat gtaaataatg
    10681 tttagaaata aatatgaata tcaaaattaa aaatagttgt gtatatttta aggaggaaaa
    10741 ttgatgtcta aggattatgc aaaattggca ttagaaatgc atgaaatcaa caaagggaaa
    10801 gtaagtgtag aaagcaaggt agaagttaaa actaaggatg atttatcaac agcatataca
    10861 ccaggggttg ctgaaccttg tttaaaaata catgaaaatc aagatgatgt ttatagatac
    10921 acttctaaag ggaatctagt agcagtagtt agtgatggaa gtgctgtact tggattaggt
    10981 aacattggtg ctgaagcatc tatacctgtt atggaaggta aagctatatt atttaaacaa
    11041 tttgcagatg tagacgcttt tccaatatgt ttaaagacta atgatgtaga tgagatagtt
    11101 aaatctgtag agttgatgga gcctgtattt ggaggtataa atttggaaga catatcttct
    11161 ccaagatgtt ttgagataga agagagatta aaaaaatctt taagtatacc tgtttttcat
    11221 gatgaccaac atgggacagc aataatagtt gcagcagcca taataaactc aataaagtta
    11281 attgaaaata aaaaaataga agatttagaa atagttataa acggagcagg agctgctggt
    11341 atagccatag caaagatact acttaatatg aatgttaaaa atataatttt atgtgataga
    11401 agtggagcat tggaagctag tatagaaaat ctaaactatg ttcaaaaaga aatgttaaaa
    11461 gtaacaaata taagaaatga aaaaggacct ttaaaagata ttataaaagg aaaagatgta
    11521 tttattggtg tttcaggtcc aggagctgtt acaaaggaaa tggttgaaag tatgtctgag
    11581 aagccaataa tattggcaat ggcaaatcct actccagaga taatgccaga agaagcaaaa
    11641 ttaggtggag catttataat gggaacaggt cgttcagact tccctaatca agtcaataat
    11701 gtactggctt ttcctggaat atttagaggt gcacttgatg ttaaggctaa agagataaat
    11761 gaagaaatga agatagctgc tgcatatgca attgctaata caataagtga tgaagaaata
    11821 tgcccagagt atatattacc agatgtattt aataagaatg tagtaaaaaa tgttgctaag
    11881 gcagttaaag aagcagcgat aaaaaccaaa gtaaatagaa tataaatttt tatatgttca
    11941 tatatcctta tcttatcggg tatatgggca tttttattat aggtttatac tcatatatcc
    12001 ttacttttat atacatatct ttatgattaa aggtgttaga aaatgtagta aattttatac
    12061 tatcagactc tatctttatt actttagtag atacatggtg gtaaaggttt atagaaaaaa
    12121 atataggaag gcagattttt attgttgcgt atatatgaga atgatataat atgaatatta
    12181 taaattaata aatttaaatt tatggaggta caagagatga tggaatataa agttaatgac
    12241 caagaactta atgcttcaat gtttatccca ttcgtcaaca ggatatggcc aggagattat
    12301 aatatggata aaacacagac tgcattatca aaaactttga atataactgc ttatgatgat
    12361 aaagtgcttg taggatgtct gcgagttctt tcagatggtt attattttgg aacaattaca
    12421 gaattgcttg ttcttccaga gtatcagaaa caaggcattg gtagtaagct tttccagctt
    12481 gctaaagaga acaccccaac tatgctatat tttggtgcac agccaggagt agaagagttc
    12541 tatgaaaaaa atgggtgcca aagaagtctg caatcctaca taataaaaaa gaaagatagt
    12601 tattaaagtt ccagctttca ataatcttaa aagtacaata ttttagtgga atcatttcat
    12661 tttttattac taatatgaca taaacatgtc atattagcat tgatatactt ttaatatggt
    12721 taagagccaa agaaaaatat aaggagtgat ttaaaatgga agaaactaaa ttttgccaat
    12781 gctgtgcaat gccaatggga caaactgatg aattatatgg gacaaataaa gatggaagta
    12841 aaagtactga ttattgtagt tattgtttta aagatggtga gtttacagct gatataagta
    12901 tggaagagat gatagaagtt tgtatccctc atatgcttca aagtaataag gatatgactg
    12961 aagatgaagc aagaacaatg atgaacaatt tctttccaac attaaaacgc tggaaataat
    13021 tttatgcaaa attagttata tgcaaaacat gaaatatggt gttgagaata aggggtggtg
    13081 tgctttatag cataccacct gttttgttac ttggagttca gttattttcc taaatatttt
    13141 aaatatacta ttttagataa gttccttctt catcttgata aattaatcct tttttcataa
    13201 gcactccaag agctcgttta aaatttttct tacttgaatt aaataatata gaaatatctt
    13261 tagggtcaga tttatcatta aatctcatat atccatcaga accttctaaa taacttaaaa
    13321 tcttattttc taaagtatca agttcatcct ttctatttcc tctaggagaa agaccaagtt
    13381 ttccatcttc atatattttt atgacatgta aattttcaag aacatcacca gtttttagtt
    13441 cagtaaagta ctcattatga agtattacac cagcatattt attgtctaca catatcattg
    13501 cagaattatt agtttggaat ccatatacaa ctccagttac aatatctcct acattgtaag
    13561 tatggtctgt taataagtat gaatctatat ctgtagtagc agcaattctt ttgcttttgt
    13621 ctaaatatat ataaaataaa tatttttcgt ctctaaatag tggataagtc ttagctttaa
    13681 aaggaactaa tatgtcttta ggaagtccca tatctataaa agtaccaatg tctgtattat
    13741 caactacttt taaatgtgct acatccccaa ccttagctaa aggcggtatt aaagttgcag
    13801 cagttctgtc atcagaatct ttaaatatga aagcatttac ttcatcacct atgtttattt
    13861 cattttttcc gattaatcta ttatgaagaa gtatatcgtc ttttgtgtta ttagtttgtc
    13921 catccaaaaa atatccaaat tcagtttttc tttttactgt aagtttatta aaatcaccta
    13981 tgtttatcaa attaaaatca tcctctcatt ttatatttat aatttagcca taatatactt
    14041 atgtagtagt ttgtcacagt atctatatta gtattagtga aatttacaat aaataatata
    14101 gttatttatg tatttttcaa ttctctagct tcttatatag tataaactcc aatttctttt
    14161 ttgtctttag gttttattaa aatttttaca aaataagtta aaaagtattg aaataaaatt
    14221 tcttttaaag tataattggt atataccaaa attggtatat accatatcga aaagtggtga
    14281 ctatatgaaa atagtaaata aatctagtaa tataccattg catactcaat taagttcaat
    14341 aataagagag atgatagaaa ctggtgagct taaagagggc gatgcaataa tgccagaaag
    14401 agaactttgc aacatacaaa atgtaagtcg tatgacagta aataaaacca ttgttggatt
    14461 agttacagaa ggacttcttt atagggtaca aggtaaaggg acattcgttg caaagcaaaa
    14521 aaagaagtat cagttttcaa atgtaaaagg ttttactgat gttatgaaag aaaagggagt
    14581 aaacataaaa acggatatat tatcctttga gatggaacta ccagatgatt tagttaaaag
    14641 aaagcttgga ataagtgata atactacaaa tatatataag attgtcagac ttagatatac
    14701 tgatggagag ccatttggat tagaaatagt atatctatca gaagaaatgt gtaagggtct
    14761 aacaaaaggg atattggata attcttcatt atatagggtt ttaaatgaaa aatatggcta
    14821 taagatacaa aaagctgaac aggtaatgga gccagtaata ctttcagatg aagaaagtaa
    14881 gcttcttgaa acagatgaag gtgctttagc tcttaaactt catagaaatt cctataatag
    14941 agaaggtagc cctatagaat ataccatatc aatatttaga acagataaat atcaatatga
    15001 aatagtattg agtgagtagg tgaataatat gaaatgttta attaatggaa agataatatt
    15061 aaaaaatcaa atcttagaaa ataaagtatt agtatttgat gaaaaaataa ttgatatagc
    15121 tgatagtgta ccaaaagatt gtgaagttat agatgctgat ggaaaatata tatctccagg
    15181 gcttattgat attcatatac atggaaacat gggaaaagat acaatggatt cgactgatga
    15241 atctattgaa acaatttcaa aatcaattat gagacatgga gtaacatctt ttctgccaac
    15301 tacaatgact atggataaag aacatgttta tgatgcactt gaagttatta aaaaagccca
    15361 aaatagaaag cttgaagggg caaaggtatt aggagcacat ttagaaggac cttttataaa
    15421 tgagaattat aagggagcac aaaatgaaaa atttataata aattcaaaat acgaatttat
    15481 aaaagaatat aaagatgtta taaaagttat aacttatgct ccagaaaaag atattgattt
    15541 tgattttact agagaaataa aaagatgtac agatatagtt ttatctattg gtcatagtaa
    15601 tgcaaattat gaccaagcta aagaagctat aaatttagga gtaactaatg taactcacat
    15661 gttcaatgca atgactggtt taaaccatag agacccaggc gttgttggtg cagcacttac
    15721 aactaatgtg tacagtgagt taatagcaga tacaatccat ataaataaag atttatttca
    15781 atttatacta aataataaag ggaaagaaag actgatttta ataacagatt ctatagaagc
    15841 tggtggtctt gaagatggca attattctct tggaggtcag aaagtcatag ttaagggtaa
    15901 tgaagctaga cttgaaaatg gagcattagc tggaagtgtg ttgtctttaa ataaaatggt
    15961 atttaacttc ttagataata caaaccttaa agtgaatgaa gcaattaatt tagcttcttt
    16021 aaatccagca acatctttgg gaataaatga caaaaaagga agcttagaaa taggtaagga
    16081 tgcagatata gctgtatttg atgagaattt agattgtaaa atgacacttt gcttggggga
    16141 agtagtatat aaaaatatat agtatacaaa acaaacctta aagacagtaa aaacaatata
    16201 aaaaataata aattaaactt acattagtaa aagtagtagt taaaatttag gaggaataag
    16261 atgagagtat tagtgtgtaa agattatgat ggaatgagta aaaaagccgc tgaaatgata
    16321 gcagctcaaa tagttttaaa accaaattca atactgggac tagctacagg aagtacacca
    16381 gtaggtatgt atagagattt agtaaaaaaa tacaatgata atatagtaga tttttcagat
    16441 gtgatgagct ttaatttaga tgaatattat aagttaccaa tatctaatga ccaaagctat
    16501 gattatttta tgaaagagaa tctatttaat catgtaaaca taaagccaga aaatactcat
    16561 ctaccaaatg gaatggctga tgatattgaa aaagagtgta tgaactatga agcttctata
    16621 gatgcagctg gtggtataga tgtacaagta cttggaatag gtcgtaatgc tcatataggt
    16681 tttaatgaac ctgatactaa atttgcaaaa agaactcatg tagttgaact tacagagtct
    16741 acaatagaag ctaatgcaag attctttaaa tcaagagaag atgttcctaa aaaagctgta
    16801 agtatgggaa taggttcaat attgaagtct aagaaaatat tgcttttagc ttcaggagaa
    16861 gaaaaagctg atgcagtata taatactgtt tacggagata taactccaga agttcctggt
    16921 tctatacttc aacttcataa agacactata gttatagtag atgaagcagc agcaagtaaa
    16981 ctgaatccaa aagattataa attagtataa gaatagaatg tagtttaagt aaaaaatagc
    17041 tatcattgag taatcaaatt tatttaatga tagctatttt tatttaaatt ttttacttct
    17101 ttttatttaa attagttatt attgtttaaa ttacttgctt attacttttt acgaaaactc
    17161 gttatcaaga agtatccaaa taagatgtta aaaattatta tgtttagtgg gattctatca
    17221 agcataataa aattacctat aattgggata ttaccaactg gaaacataaa gaagaataca
    17281 ggcatcagtg atagtaaaaa agatggaaaa caaagaagaa gtaatcttgg aatatcaata
    17341 taccaactac catccttttt gtattctcta atcaataatt cagttcctag taataaacca
    17401 ataccaccag aggaaattaa attaataaaa atgtatcttt taaagtcttg catataacca
    17461 gtgtaaaatt gagtatagaa atcataattt aatttaacgg ctaaaaaata cataagcaat
    17521 agaatgatta aaaataaaag atatctaaga gcttttttca ttttaaattc tcccttcaga
    17581 aatactttat ttagttttat tttgttggaa tctgatttta tcatttagtt taagaaatcc
    17641 ataatattag tgaagaatga aataagtatt atatatgaat aaatattttt agaattaagg
    17701 tgaattgtag tgcttaatat aactataata ttaattgttt gaatattcaa taaaaagttt
    17761 gaaaaatatc aattttgata taaactgaat aaatacagtt gaatattaaa ttattatttt
    17821 atcaaaaata tgcaaagtac tacaccttca aatatcacct aaagtaatta aaaggcaatt
    17881 aaggtgaagt agttcaagta tttctaaaat aagtttaata aattctataa taatttattt
    17941 tttgccttaa aattgcctta aaatccaaac aattttaaaa ctaatgtact ataaaaagct
    18001 ggtataattt aaatatagta aaaaataaga tttatcttat ctattgggat ttaattattt
    18061 aatcaatata tttataccat ttaatttaaa taaaaagtct attaaggagt gagcttatga
    18121 gtaagttaat ttatatagca gatgatgaag ataatataag aaatttggta aagacattct
    18181 taaaaaatga aggtcatgat gttatggatt ttaaaacggg tgatgaactt ttagaacaat
    18241 ttaatataaa ggagtgtgac ttagtaatac tagatataat gatgcctggc tcaagtggtt
    18301 ttgaagtatg tacaaaactt cgtgagaaaa gtacagtccc aataatcatg cttactgcaa
    18361 gagatacaga tatagattat attacaggga taaccttagg tagtgatgat tattttacaa
    18421 aaccatttag cccaatgtct ttggttatga gagtaaaatc tatatttaga aggatagagt
    18481 ttgaaaagaa acaaaattat gataaatata gtaactcgat agatatggaa ttaaaatttg
    18541 gtgatgtaat aataaataaa aagaataaaa tcgttacaag taaaaatgta aatatagacc
    18601 ttacaccaaa tgaatataac ctattgactt atttgtttga aaatatagat agagcagttt
    18661 ccagagatga attattaaac aaaatatggg gatacgatat agaagttgag acaagggctg
    18721 ctgatgatac agtgaagaga ttacgtaaaa aaattttaaa tacaaatatt ttaatagaaa
    18781 ctgtatgggg gtttggattt aggttgaagg agaaaagtta agatgaagaa tggaaatgac
    18841 aagaatagaa ttggaaagat taaatccaaa tttaaattaa agttctcaaa gaaaaatata
    18901 agcataaaaa ctaggatttt gttgagtata ctttgtttga taattatagt atttatgata
    18961 atattagtat cttttaatgt atttcttgat acatatataa aaacaactgc gaatgaagaa
    19021 ttgacaaagt ctacagaaat agtagaacat atggatagta attttagacc tattaagcca
    19081 ccacaagatg atggaaagct tcctcccaaa gtattatcta attttatgag aaatgtacaa
    19141 gataaagtta ggatggcaga aacacaatca gatgctgatg ctatggtagt tgattctaag
    19201 tataacctga tatttccaac aagagaggat gatttcttaa aaaatgttga tgagatggag
    19261 ctgattaggg agtgtattca aaatgaaaaa ttagatttaa attcagatgc aaatacacgg
    19321 atatctacca gaaataagga ttattatatt tcaactgtaa aaattactag tatatatggt
    19381 gaacaagaca agtatcttat actttttata gacatatcaa aaactctaaa tctagcacaa
    19441 aagataaata ttgtattaat atctgtaatg tgttttgctg gaatattagc aatatttaca
    19501 gctgtgattt tatctgagaa aattgctaaa ccgataaaag agttgtgtga gtttgcaaaa
    19561 aaaatgggtc aaggagattt caaaagaacc tactttgact tttcagataa agaattagta
    19621 gagctctcaa ctgttatgaa taagagtgct gagtatctgg ataagtatga taatgaacaa
    19681 aaaatatttt ttcaaaatgc atctcatgaa ttaaggacac cacttatgtc tattaaaggt
    19741 tatgcagaag ctataaaata taatgttata gatagtaaac atgcaagtga tataattctt
    19801 gaagaaagtg ataggttaag tgatatggtt gaagatttat tatacatttc taaaatagat
    19861 aatataacta aagattttga acttgtagaa tgtgatttaa gagaagtact ttcaaattgt
    19921 ggagctaggc aaaatgtaag agctataaat aaggggataa aatttattta tgaatttgat
    19981 gaagaaatgg ttttatttga atgtgatgaa aaaaacattt ccaaagcatt tatgaatctt
    20041 atagaaaatg ctttgagata cgctaagagt gaaataaaaa tagtgtgtaa gtataatcaa
    20101 aaaaatatag ttgtgataat agaagatgat ggaattggaa tcaagaaaga agatttacct
    20161 catgtttttg aaagattcta taagggagta gggggaaatc atggaattgg attatcaata
    20221 gttaaatcta ttgtaaataa gcatggtggg cgtatatacg tagaaaatgg caaaaaagga
    20281 gctaaattta ctatattatt taaattgtaa aaaaattaga gaaaatatag agatgtttga
    20341 agttgttttt tatatatatc tgttgtatac tgttgaaaaa agaacaatat taagctgaca
    20401 tatattacga tagttgacat ttaaagtaaa tgcttaaata tagatacgaa aggaaaagta
    20461 aaatctgaag tgtatttagg tttaagtaag cttcttattt tataaaaaat atgtatgaaa
    20521 gaacagctga tttttaatat tacaaattta gtaacggttg tatttgaagc ttttgtcatc
    20581 catatgtttt tatcagactt tttaggccag aaagaagggt atataaaagt tgtaagatat
    20641 gctaaactgg gttttataat atgtttagga ttctgtaatt taataacttt aaaccctaaa
    20701 atcacaatgc ctttaatttt catccttatt ttttcaacat catttttata taaaggaaat
    20761 ttaaagacac gattgtttac tactgtttta ttaagtatat tctttatact gtcagaaatt
    20821 gtagttacaa gtatttttgt tttatttgta aaagaaggct ttgaaataat gcttgaaaat
    20881 aatagtataa gagtattggc gacaatttta tctaaaattg tctttttgtt gacttgtaaa
    20941 attatttgtc tatttaaaaa agatgtacat ttagatatgc ccataaagta ttggctccct
    21001 ttatttttaa tacctatatt tagtttattt ctgtctgttt ctatctttga tgtaagtaaa
    21061 ttttttagtc ttgaaagttt aaaatttcta agcttaatat ctagtgttgg tattttatat
    21121 attaatttta ttgtctttta tttatttaaa tttattatag ataaaactaa actatctatg
    21181 aaatatgaac tacttgaaaa agaaataatt cataaggaag aattaagact tagtaatgag
    21241 tgttataaaa ttattgttga acagactgat tctgtcgttt tcgaatggaa tatcaaagaa
    21301 aataaatcat ttgtatcgca ggcttggact gaaaaatttg gatataacaa tgcatgtaag
    21361 aatattttta aagaaattaa agataaagac ttagttcatt ctgaagataa agctatattt
    21421 gaaggttttc ttgaaagtat taaaaaaaag aatatgcaca atcaagcagt atatcgttta
    21481 aaaaaatcta atggtgaata tatttggtgt agaacatcaa ttacaagtat ttataatgat
    21541 gaaaatgaac ttttaagagt tgtcggagta attgtagatg tagatagtga tataaaaaaa
    21601 tatgaagagt taagaactag agcagaaagt gactcattga ccaatatata caataaaggt
    21661 acatttgaaa aattagtgga agaaactata gttatgaata caggtgataa aaaagatgca
    21721 ttattcatta ttgatttgga tgattttaaa gaaataaatg ataattttgg tcatccattt
    21781 ggtgattttg tactaaaaac atttgctgat aagatacaaa ctagttttgg tagtaaagac
    21841 ttagtcggaa gaattggtgg agatgaattt gttgtatata tgcaagatta tgttacagaa
    21901 gtaaatttgc ataaaaaagc taaagaatta aatagagtac tttcggataa ttacactgat
    21961 ttgagtttta gttttgatgc ttctgtcagt ataggtattg caaggtatcc tcaagatgga
    22021 acttcatttt ttgaattgtt taaaaatgca gatagagcac tttatagcat aaaagcatca
    22081 ggtaaaaatt catattgttt atttgaagaa gaactatatg tacagtgaat ttgaatttag
    22141 attttatgtg agagtaagat ttatatatac ttgtggctgt ctgatttata aaatatgtta
    22201 ctttgtatat ttttatatgt ttcagtaagg ttaattaaca tgagcaaagg tgtaagtaaa
    22261 tttatattag tttaagttta cttacacttt tataaaaata caaataatag attcatttac
    22321 attcttaaat aattaaagct ctttaccttc taaacatgca taacatatcg ttataattcc
    22381 agtaaataag actaaaatgc ccattcctaa gattacaatt tcatcatcta ttactccaaa
    22441 tgtttttaaa gtaacttatt tcgctttgta tcataataat ttgtctcctt ttacatttta
    22501 acttctgctg agatttgagt tagatattca ttagaatctc gcacacttat atcatataga
    22561 agatattctt cataaacaaa atccccaata cgtaaattat tctgattaaa aaaatttaat
    22621 aacttttcat aagtcttgta aatagtttca taactccctt tatgataagc agttacataa
    22681 agtccctttg gtttgattga tacaggatat ttcttgtact ctttattaac ttttgtaaat
    22741 aaatatgaat atgattcaaa gtctttatta attatatctt cacctttaat gattgagcca
    22801 atcgtaccat aatcactcaa ttcatagttg tccataaagt taatacattc atataaaaaa
    22861 ttttcttcct catctcctaa aaactgttct ttatatgtaa caggtgtttt gaccaagtac
    22921 tcttcttcat gttcttttaa agtaatagta ttcgcatcta tattacaagc atttttagtg
    22981 aatgaaatag tagattccat tagagcttga atattattta gtttttcaat ttcattttta
    23041 atatcaatgg ttttcttttc taaaagctca attagtaaat taggtgttct tttgtctata
    23101 taagctttaa tttcttttaa aggcattttt acttccctaa gtgaagaaat tataccaaaa
    23161 atgctaagtt gatggtatga gtagtatcta tatccatttt ctttctttaa ttctggtgag
    23221 aaaagaccta tatcatcata atggaaaagt gtttttttat tgattccaca aatctttgca
    23281 aattctccag ttgtaaaata attttttgaa acttgactca taattataat tcctccttga
    23341 ctatcctgtt acagtatagt ttatcatagt attttgtaaa ggagtgtgat tatatgaaaa
    23401 aattaattca ttttttaaaa ccatatagag ttttaattgt tgtagttttg atatttacgt
    23461 ttttacaaac acttggaact ttgtatatac caacacttac agcaaatata gtaaacaatg
    23521 gtgtagtaaa gggagatata gattatattg taaaaacagg tttaatgatg atgatagtag
    23581 ctggtataac agctttatca gctgtgttag tttgtaaagt atcagcaaat ctttcatctg
    23641 gattttgtag agatattaga gaagcagtat ttataaaatc acaagattta tcaataaatg
    23701 attttaataa tataggtaca gcatcaatga ttactaggag tactagtgat attactttaa
    23761 taggtcagtc tgtgtttatg tttattcaat tagtattacc agcaccaatt ataactgttt
    23821 ctggtctatt cttagcatat tctatagata aagcaatgac aattattatt gttgtagtaa
    23881 tgtttttatt catgctttca gcatttttag ttggtaaaaa gcttataaag ttgtttaaaa
    23941 tgatgcaaat aaaaatggac aatatgaata gggtgttacg tgaggtagta actggagtaa
    24001 gagttataag agcttttaat aggagtcgtt ttgaaaaaaa gagatttgat agaactgcaa
    24061 tagattattc tgaaacagca atttcaataa ataaaatatt tgcagtactt atgcctattg
    24121 taatgttaat aatgaattta ggtatagtaa gtattatttg gtttggtggg atgagagtca
    24181 gtaatggaaa tatggaaata ggtcatataa tggcacttgt tgaatattgt atcttaattt
    24241 tattctattt aatcatggga gtaatggtat ttatgtacat acctagagca ggtgcatgtg
    24301 cagatagagt aaatcagata ttagatatag aacctgaaat tgtagatgga aatggtcata
    24361 aagatactgt ctcagagaga ggacatttag tatttaaaaa tgtaaccttt tcatatgcac
    24421 aatcagaaga acctgtgtta aataatataa catttgaagc aaaatctgga gaagtaactg
    24481 caattatagg aagcactggc tcaggcaaat ctactattgc aaatataata ccacgttttt
    24541 ttgaaattca atctggagaa atatctataa atggtcagga tattaagaag attcctcaaa
    24601 aagaacttag agataagatt ggatttgtac cacaaaaagc ttttttattt agtggaacaa
    24661 tagaagaaaa tataaggtat ggaaaagaag atgcaagtat tgaagaagta aagcatgctg
    24721 caagtatagc tcaagctgat gaatttattt ctgatatgga agacaagtat gactcatttg
    24781 tagcacaagg tggaaataat ttgtcaggtg gtcaaaaaca gagaatatcc attgcaagag
    24841 cgttagttag aaagcctgaa gtatatgtct ttgatgatag tttttctgca ttagatttta
    24901 aaacagataa aagacttaga aaagcgttga aaaatgaaat caaagattca tcagctataa
    24961 ttatagcaca acgtataagt acaatcatgg atgctaatca gattatagtt ttaaatgatg
    25021 gaaaaattgt aggtattgga aaacataaag atttacttga aaattgtgaa gtttataagc
    25081 aaattgcgga ttcacaactt agtaaagaag aacttgcata agatgaagaa ttaatctgat
    25141 atttggaggt gtatgatatg agtgaaaaaa gaatagatga acaagatata gaagtactta
    25201 gttttgaaga tggcatgtca gcagaaaaag ctaaggatgc aaaaaaaact actaagagat
    25261 tattaaaata tatggcaaaa caaaagttta aaatattaat tatttttatt tcagtattga
    25321 taagttcagc gcttacagtt ttagcaccta tggttatggg aaaagctatt gaccaactat
    25381 ttaatggaat aaaaactgca gtccaaacag gtacaaaatt cagtgtgaat tttagtacta
    25441 tggggggtat agtatcaata cttctagggt tgtacttaat tagtgcagta tttatatata
    25501 ttcaacagta tattatgtca ggagttgcac aaaatctagt tcttagcatg agaaaagatt
    25561 taagtgataa actcaataaa cttcctctta agtactatga ttctcataaa aagggggaaa
    25621 cacttagtat agtaacaaat gatttagaaa aagtagcaga tagtttacaa gaaggattaa
    25681 tgcaacttat tacagcagta gttacagtag ttggttctat tgtaatgatg ataagtataa
    25741 gtgtaccact tacaatagta tcagctataa cattacttgt ttcattgggt attactgttg
    25801 taattgcaag aaaatcacaa gaaagattct ctgaaaatca aaaggcacta ggagagttaa
    25861 atagcaatat agaagagata tttactggtc aaatagtggt taaagcattt agtaaagaaa
    25921 aggatactat aagaaacttt aaaatattaa atcaaaatct ttataatgca agtagaaaag
    25981 cacagttttc gtcatatgca atatctccaa ttattagatt tataaaccta attggctatg
    26041 ttattatagc agttgtaggt gggatatttg catcaactgg agcaatgact cttggtagta
    26101 tacaagcgtt tattcaatat gtaaatcaag catcagagcc tactacagaa atatcttata
    26161 ttgtaaatat gcttcaagca gcaatagcat ctgcagagag agtttttaca gttatggacg
    26221 aggtggaaga gataaaggat gaagaatctt caaaggttat tagcatgcct aaaggtaaag
    26281 tacaatttga gcatgttaaa tttggatata gtgatgattt tattcttatg aaagatatta
    26341 atatcaatct aaatgcagga gataagattg caattgttgg acctacagga gctggaaaga
    26401 caactcttgt aaatttactt atgagatttt atgagataca aggtggaaga attactattg
    26461 atggtgttaa tataaaagat ttaaagcgtg gagaacttag aactatgttt ggtatggttc
    26521 ttcaagatac atggctgttt aatggaagta taaaagaaaa tattgcatat agtaagtcag
    26581 atgccacaat ggatgaaatt gtaagagcag caaaatcagc aagagtagac cattttataa
    26641 ggactttacc acaagggtat gacactatat tgactgagga tgcttctaat ctatctcaag
    26701 gtcaaaagca acttctaaca attgccaggg caatactttc agacccatca gtattgattc
    26761 ttgatgaagc aacatctagt gtagatacta gaacagaggt agaaattcaa aaggcaatga
    26821 ataacttgat gaagggaaga actagttttg ttattgcaca tagattatca actattcgag
    26881 atgctgattt aatattagta atgaaagaag gaactattat tgaacaagga agccataagg
    26941 aacttattga aaagaaagga ttctatgaag aactttataa cagtcaattt acaagtgaat
    27001 atgatgaaga tgttgtatga ttatcaagtt ttaggcaact aaatgattga taaatattaa
    27061 gttaaatata gtaacatgta aggttatatg gaataagagt atttctctat ttcatataac
    27121 cttttttatt tatcaaaata agataaaatt tcctttctaa attagattga agaatgtatt
    27181 tatcaatata aaagtaaaat aatcattatt attagtgaag taaatattgt ttgccacata
    27241 tatgccataa agatgcactt attttacgga gatttaacaa agtagtgtaa agtatactct
    27301 aaatataaaa taaatcaaat agagttaaat aaattgagag gtgatataaa tagtgaataa
    27361 aaaattgaac tatagatttg aaatgaagca caaaataact gaagcagatg tgttagcttt
    27421 aaaatcaaga ctctatccaa taatgaagaa agatgaaaat gcatctaaag atggaaaata
    27481 tcttattagg agtttatatt ttgatactcc tgaagataaa gcacttttgg ataaattaaa
    27541 tggcgttgca ataagagaaa agtttaggat aagattttat aataatgact gctcttatat
    27601 aaggttagag aaaaaaatca aacattacaa catgacatca aagctatcaa ctaatttaac
    27661 caaaaaagaa gtaataaata tactaaataa tgatattgaa tttctaaaag agtcgacaaa
    27721 ttgtttatta agagaatttt atttgaaatt aaaatgtgaa agattagagg caaaaagcat
    27781 agttgattac aatagagaag cttttattta tccagttgga aatgtaagag ttacaatcga
    27841 tagtgatatt aaaacttctg taaattcggt agatttattt aataaagatt tgccaactgt
    27901 ttcggtaatt gatgataata tgactgtatt ggaggttaaa tatgatgaat ttataccaga
    27961 ttttataaag gatttaattc aaattaataa gactacctct acagcagttt caaagtatgc
    28021 ttcaagtaga ttatatattt aagaataaag gctatgattt atataaagat atacataaat
    28081 aaggttaaaa aacaaataag ttaaaaataa ataaaataaa aaataaataa gttaaaaata
    28141 ggaaggatga ttttaattat gacatttaat gatattttta aatcaagttt tatagaaaac
    28201 gtatcaggtt tttcatttgt ggacagtgct ttagcactag gttcagcttt tttagtaggt
    28261 ttatttatat atatggtcta taaaaagact tatatgggaa ttatgtattc tcgaccattc
    28321 aatgtgtcgc ttgtagcact tacaatgctt acaacttttg taatattggc agttacttca
    28381 aatgtagttt tatccttagg tatggttggt gctttatcta tagtaagatt tagaacagca
    28441 attaaagacc caatggattt agtatttcta ttttggtcat tgggttcagg tatagtttta
    28501 ggagcaggtt tgattccctt agctgtcatg ggttcaataa ttatgggatt gattctaata
    28561 ttcttttcaa ataaaacaat atctgaaact ccatatatat tgatggtaaa ttgtaataat
    28621 gaagattcag aagatatagc aactgataaa attaaaaaag tatttactaa atatcaaata
    28681 aaatcaaaaa gtgttacacc agaaaaagga atagaattag tgtttgaagt aagaatgaaa
    28741 gatggagaaa caagtcttat aaatgacttg agtcaagtag atggagttac taatgcagtt
    28801 cttgtaagtt ataatggtga ctatgtagca tagagaggag taatctttta tgaaagataa
    28861 aaaatttacc cttcttatct cgattatgat tatattttta tgtgctgtag ttggagttta
    28921 tagtacatct agcaacaaaa gtgttgattt atatagtgat gtatatattg aaaaatattt
    28981 taacagagac aaggttatgg aagttaatat agagatagat gaaagtgact tgaaggatat
    29041 gaatgaaaat gctataaaag aagaatttaa ggttgcaaaa gtaactgtag atggagatac
    29101 atatggaaac gtaggtataa gaactaaagg aaattcaagt cttatatctg tagcaaatag
    29161 tgatagtgat agatacagct ataagattaa ttttgataag tataatacta gtcaaagtat
    29221 ggaagggctt actcaattaa atcttaataa ctgttactct gacccatctt atatgagaga
    29281 gtttttaaca tatagtattt gcgaggaaat gggattagcg actccagaat ttgcatatgc
    29341 taaagtctct ataaatggcg aatatcatgg tttgtatttg gcagtagaag gattaaaaga
    29401 gtcttatctt gaaaataatt ttggtaatgt aactggagac ttatataagt cagatgaagg
    29461 aagctcgttg caatataaag gagatgaccc agaaagttac tcaaacttaa tcgttgaaag
    29521 tgataaaaag acagctgatt ggtctaaaat cacaaaacta ttaaaatctt tggatacagg
    29581 tgaagatatt gaaaaatatc ttgatgtaga ttctgtcctt aaaaatatag caataaatac
    29641 agctttatta aaccttgata gctatcaagg gagttttgcc cataactatt atttatatga
    29701 gcaagatgga gtattttcta tgttaccatg ggattttaat atgtcatttg gtggatttag
    29761 tggttttggt ggaggtagtc aatctatagc aattgatgaa cctacgacag gtaatttaga
    29821 agacagacct ctcatatcct cgttattaaa aaatgagaca tacaaaacaa aataccataa
    29881 atatctggaa gagatagtaa caaaatacct agattcagac tatttagaga atatgacaac
    29941 aaaattgcat gacatgatag catcatatgt aaaagaagac ccaacagcat tttatactta
    30001 tgaagaattt gaaaaaaata taacatcttc aattgaagat tctagtgata ataagggatt
    30061 tggtaataaa gggtttgaca acaataactc taataacagt gattctaata ataattctaa
    30121 tagtgaaaat aagcgctctg gaaatcaaag tgatgaaaaa gaagttaatg ctgaattaac
    30181 atcaagcgta gtcaaagcta atacagataa tgaaactaaa aataaaacta caaatgatag
    30241 tgaaagtaag aataatacag ataaagataa aagtggaaat gataataatc aaaagctaga
    30301 aggtcctatg ggtaaaggag gtaagtcaat accaggggtt ttggaagttg cagaagatat
    30361 gagtaaaact ataaaatctc aattaagtgg agaaacttct tcgacaaagc aaaactctgg
    30421 tgatgaaagt tcaagtggaa ttaaaggtag tgaaaagttt gatgaggata tgagtggtat
    30481 gccagaacca cctgagggaa tggatggtaa aatgccacca ggaatgggta atatggataa
    30541 gggagatatg aatggtaaaa atggcaatat gaatatggat agaaatcaag ataatccaag
    30601 agaagctgga ggttttggca atagaggagg aggctctgtg agtaaaacaa caacatactt
    30661 caaattaatt ttaggtggag cttcaatgat aataatgtcg attatgttag ttggtgtatc
    30721 aagggtaaag agaagaagat ttataaagtc aaaataagat taaaattgaa tataaataat
    30781 tttaatactg ttaagtctaa atatttactt agcagtattt ttttagaaaa taatgtattt
    30841 ggt
//
LOCUS       DAMJXI010000041        30806 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.043, whole genome shotgun sequence.
ACCESSION   DAMJXI010000041 DAMJXI010000000
VERSION     DAMJXI010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30806
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.043"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            165..1316
                     /locus_tag="PC465_002431"
     CDS             165..1316
                     /locus_tag="PC465_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2649717.1"
                     /translation="MELRPRSAKLEEFDKVIELINYVFRISRNHKPTMMEEFPLLLSK
                     NNIENMIIISEDDKVVSDVNYLIQDVSIQGNRLKVAAIGGVCTHPDYEKRGYSSKILD
                     KVEEKMFYDGVDIVIISGTRSLYSRRNCSLVKSFYKYTIKPEDVKIAYEIVEFDETNF
                     EKDNDLDKMIELYNQNSTRFIRTRDEFQKLLHAATIAWGPIGYKKVFIKENNNIIGYL
                     IIRTIKKEDSTVGEVAEIGLNSVNVENILKYVANKFGLEYLNYKVHVKNLKDQLKCNG
                     TKSLDYQQGTMKIINFTKLCDSLRSYFSQYVDFELLKYMEFKQVENKYIIKYKEEELV
                     IENLDKLNKLFFEKNEEQYNDFKHLKNIYEFATKAFPVDFPWTANLNYQ"
     gene            1434..2072
                     /locus_tag="PC465_002432"
     CDS             1434..2072
                     /locus_tag="PC465_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423639.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HDF2649718.1"
                     /translation="MDILDDIAECILNMGVDNIENLVKIAIDKNIDVEDIYEYGLNKG
                     MIGALDKFENKEYYLSEVIVCTDALNKGINLLKGTGKVKKKSKGVILMSVVEGDTHEI
                     GKNIVKVMVEATGYKVIDLGVNRKSEDIIEEAIKNNVDIIGLSSMMTTTMENMKSVID
                     ELNMIEIDKRPKVIIGGGPVSMEFAEEIGADGYSSNAPKAVKLINKLIGGEV"
     gene            2073..3095
                     /locus_tag="PC465_002433"
     CDS             2073..3095
                     /locus_tag="PC465_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HDF2649719.1"
                     /translation="MFSDMTLLQYINSEDRGFFLPDMGTNGLFLINKKAYEVYDSVDL
                     QLELAKTMDKYFESDFIYSFCDGITFCETLGLETLRPDYDFPSVLTHTITDRDKLRKL
                     DVPDPYTSGRMPLNIESLSVISKSIKKPLYESIQGPFTLAGQLAGATQLLRCIITDKK
                     FVEELLEFTTELVRRYAVAANKAGAKYISIAEPTSVTLSKDRFDEFIVKNLNKIYNEL
                     DCWKGMHICGDTRELLDNMLSCNIDAVSLDQILDYEEIAPMIPRDIVLIGNLDPIKLL
                     GRSKPDKIRRETLKLLKKMRGYDNFLCDFGCNCLNTTPVENLQAAIKAGRISYKELDR
                     IDIDEL"
     gene            3085..3705
                     /locus_tag="PC465_002434"
     CDS             3085..3705
                     /locus_tag="PC465_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649720.1"
                     /translation="MNYNSNKNKYLLKDINLDDIFIDKNIVLKFLGYGNRKAPDTISK
                     IVEREIRNINDILDIKIYISEVDINKTPKECKKAFAVLYTIGDKIDIKMNDYMENCNM
                     MAGLALDKIGIVCLDCINEKIKMYLKGKYDSLKISHEIYPGDKDFEVERQKDIYNYVK
                     NKYNSIEIEINDYHQLSPIKSVAMLILMGDEENLESRCSKCPRKCF"
     gene            complement(3829..4515)
                     /locus_tag="PC465_002435"
     CDS             complement(3829..4515)
                     /locus_tag="PC465_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HDF2649721.1"
                     /translation="MKTYKFIFFDADDTLFDFKKSESHAFKKLLSEFDLEFNFENYIE
                     SYRNISDKLWLDLEKNIITLNELKLLRFELFANKISLDVDSETLSKMYLNFLGECTFL
                     IPGAIDILQYLKKKYTIVIITNGISAVQKKRLENSKIKEYIDGMVVSEELKISKPNPE
                     IFKYALKKFNCHDKSSALMIGDSLTSDVLGGINSGIDTCWLNSNNSINYTNHIPTYEI
                     NTLIELKKLL"
     gene            complement(4529..5074)
                     /locus_tag="PC465_002436"
     CDS             complement(4529..5074)
                     /locus_tag="PC465_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2649722.1"
                     /translation="MNDLNLGEKIAEVRKKQNLSIRDLAKLADVTPSLLSQIERGLAN
                     PSVNSLKSIASSLNVPLFTFFVSEVDKKNLIVRHDNRKKVILPGSKEVIYEILIPDSS
                     GNLEFAIMDLAPNTSSCVDRITHNGDEIAYVLEGEVKLFMDDDEFTLSKGDSVKVPLG
                     TKHKWQNDSNSESKVIFAVIL"
     gene            5302..6549
                     /locus_tag="PC465_002437"
     CDS             5302..6549
                     /locus_tag="PC465_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF2649723.1"
                     /translation="MQITTFGAIFGLLIAIILIIKKFQAVYSLMLGAFIGGLVGGANI
                     TQTVDFMANGAMNISPSILRALASGVLAGSLIKTGAVDKISEQIVKIFGEKRALFSIA
                     ISTMVLAGVGVNLDVSIITVAPIGLYIGRKLNYSKLSILLAMLGGGKAGNIISPNPNT
                     IAVADNFSVNLSSVMMANIIPAIIGVVITVILASILINKGNKVQSYEILEQREDLPSL
                     FKSLCGPIIAIFLLFLGNVSPIVIDPMIALPIGGIVTLIVTGNLNNSREYLAFGLSKM
                     QGVCILLLGTGTIAGIIQMSELQQSTIGALQFLNMPQFLLAPVSGILMSLATASSTAG
                     ATIASSTFHDAIINGGLSPISGASIVNAGSSVFEQLPHGSLFHTSSGSINMDIGERFK
                     LIPYEALIGIVMTIISTSIQLVL"
     gene            6636..8630
                     /locus_tag="PC465_002438"
     CDS             6636..8630
                     /locus_tag="PC465_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF2649724.1"
                     /translation="MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPF
                     TEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYKGIIVDLINSLSIQIGRDFYFKP
                     NNWWKESFVNSIDDSIKFFDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMD
                     LKGKTVAIPEGDYSINFLKQKIQDINILLTPDIKTGVNHLMSGKVDAVVGDEPVLRYY
                     INNYGLSNKYSVLSNPIYTKKAVLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWY
                     STYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEIKRKTEQVIENKKTL
                     EATFNSITDIIMLVDENNNIVESNKVLYDFMGEMSYKIADLISMIKGVIENTFSENTN
                     KTSEIEIHNKILKINTFPVEYKKNNTEYIVVLIKDITNDKIVEAKLLRENKMISIGQL
                     ASGVAHEIRNPLGIIRNNCYLLKDNVTMEEVNDCVKSIESNVDRASNIITNLLNFARI
                     SDDNLEHINIRNFIENIVKLQYKMLQLKNVEIKIDCEHNLICYINGESLKHVFINLIS
                     NSIDAIHQDGKIIIYCYEKNHCLFIDFKDNGEGIKEDALKDIFNPFYTTKPIGEGTGL
                     GLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNKEVTI"
     gene            8630..9952
                     /locus_tag="PC465_002439"
     CDS             8630..9952
                     /locus_tag="PC465_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HDF2649725.1"
                     /translation="MKILLVDDELEYGVVMKKILQKKGYLVDIALSGEEAINIIKKDK
                     NYDLVLSDVMMKNMDGVQLLDRIKSINRDIEVILVTGYGSIENAVDAMKRGALSYFIK
                     SNPIENLLEEVEKVKASKISVSVQKNNLEFTLESKNRDFNNIIKIAKKAACKDVNILI
                     LGESGVGKDILARYIHSISPRKNEIFVPVNCCSFSENLLESELFGHEKGSFTGAVDSR
                     KGRFELSNKGTLFLDEIGDIPLNVQVKLLRTLEDKSIERIGSNKSIKVDFRLICAMNK
                     EPKVEISNGNIREDFFYRISTITITIPPLRKRREDLTTLIEFFLNKYQIEHDKKIHSI
                     DKEVKDFLLNYNYPGNIRELKNIINRLVVLSEEGNLSKDNLNLISNNVYIDDKISIRP
                     LREIRKEFECEYIEKVLSLCGNNISNTAKKLEISRRQLTNKISEYNIK"
     gene            10231..11517
                     /locus_tag="PC465_002440"
     CDS             10231..11517
                     /locus_tag="PC465_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006807454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HDF2649726.1"
                     /translation="MKLELGNIFIKNVEFGEKTEVKDGVLYISSEEIEKIVLEDERIV
                     SVNVELARPGESIRIAPVKDVIEPRVKIGDESKIFPGIINKVKTVGSGRTHVLLGACV
                     VTCGNIVGFQEGVIDMSGPTAKYTPFSKTNNICIVIKAKDGIDTHDYEEAARIAGLKI
                     GAYVGEAGREVEPDEVIVYETKPLLKQVKEYPDLPTVAYVHMLQSQGLLHDTYYYGVD
                     AKQIVPTFMYPTEIMDGAIISGNCVAPCDKVTTFHHLNNPVIHDLYKRHGKDLNFIGV
                     ILTNENVFLVDKERSSDMVAKLIEFLGVDGVLVTEEGYGNPDTDLMMNCRKCSEVGAN
                     VVLITDEFPGKDGKSQSIADATKEADAVVSCGQGNLVVHFPAMEKIIGTLDYVEMMIG
                     GYKGCLNEDGSMDAELQIIIASTIANGYNHLTARYY"
     gene            11603..12910
                     /gene="grdB"
                     /locus_tag="PC465_002441"
     CDS             11603..12910
                     /gene="grdB"
                     /locus_tag="PC465_002441"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:12650..12652,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HDF2649727.1"
                     /translation="MSKIRVVHYINNFFAGIGGEEKADIPPEKRAGVVGPGIAFQSQF
                     NDGAEIISTVICGDTYFGENIESATQELLKMIKEESPDLFIAGPAFNAGRYGVACGTI
                     CKAVEEELNIPVITGMYKENPGVDMFKLDLHIVSTGNSAASLRKVVPIMTKLGLKLVR
                     DEEIGPPEEEGYIMRGIRKNFFHELRGSERAIDMLVKKMKGESFETEYPMPEFDRVTP
                     MKPVKDLSKIKLALVTSGGIVPIDNPDKIESSSATKYGIYDLTDMDSMSNKEFTTIHG
                     GYDRAYVLENPNLVVPLDVVRELEKEGVIGELVDYFITTTGTGTSVGNSKRFGEEFSK
                     KLLEDDVDAVILTSTUGTCTRCGATMVKEIERAGIAVVHICTVVPISLTIGANRIVPA
                     VGIPYPLGNPMLGEEESKKIRKNIVLKALNALTEDIEEQTVFE"
     gene            13198..13929
                     /locus_tag="PC465_002442"
     CDS             13198..13929
                     /locus_tag="PC465_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2649728.1"
                     /translation="MIRKKVYILISIAICDDESYMLNHLKENIELYMKQKNLLYNIEL
                     FNKVEDLLCNHEKFNIVFLDIQMEEINGMQAARKLRSYGNECFIIFVTVLNEFVFDAF
                     EVDAINYLIKPLSNEKLYKTLDKIVTKLEDNESNYITIQKGYSYWKLKLADILYCEVI
                     KRKIYVHLKKETVDYYETIENLERSLPTNFFRCHRSYIINLQYVYGYENGNAVMESGD
                     RIPVSRLRQQIFSKVMLEFMKNRRI"
     gene            13931..15289
                     /locus_tag="PC465_002443"
     CDS             13931..15289
                     /locus_tag="PC465_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2649729.1"
                     /translation="MINLFSSDLFLKYSFLFSFIVYRILMVIVQYYFLISFTNVNSKF
                     WCFILYSIISIFLIIINTYFNLYNLFSSQILFFLMTFLFVKYIIKQSTVLSIVSTLLV
                     YLIEQLVYGFTAPLNYLIFTSDINTDIYKFDINMGLSSLITIIIAGFIYWYSSKKFNI
                     KVMNFDKYIAILMIPLLLIILFMQSFEYSSNINIDTSLGIVKLLLNTSITEEIQAFLF
                     SIIGTICVFFSLFTFKKLIQALEDDKERAIMNQQIHAQKNYIEEAKSRLSQTISFRHD
                     FNNHLAIVNGLLKKDQILKAQDYLNKLEKVTSDLSFSCNTQNIVIDALFNNKLSIAKQ
                     LGIEVDCEVIIPQSTNMNDFDLCIVFANAIDNAIKACRVVDKQNRYLKLSTKLEGGFF
                     MIEIKNSYNPINNYTRGSGIGLLNIKEIAKKYQGAISIDKTSDYFQINVLLVISLHCA
                     SI"
     gene            15328..15813
                     /locus_tag="PC465_002444"
     CDS             15328..15813
                     /locus_tag="PC465_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649730.1"
                     /translation="MYLNRESLIYRNEEVTKMKVGNINGQAPITNGLDSCQSEVQGLE
                     QRKKSLQDEIEKVRSDKSIDGETAKLKIEALKKEMEEIENKIQELKGNKAKKTNKEEN
                     NVSEVNNNLLERKKEPSNNENVKQLYDVFERSNVDEQWDNTYRVLQDDKNLKVKFNRP
                     I"
     gene            complement(16076..16312)
                     /locus_tag="PC465_002445"
     CDS             complement(16076..16312)
                     /locus_tag="PC465_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649731.1"
                     /translation="MLLTHIYFNGQFKQTIELYKQAFNATVKTLIEDSCYLLIVHNEI
                     VIHNKFLILNDFGNKNGVSISEGYQPTYKIQTAS"
     gene            complement(16467..16691)
                     /locus_tag="PC465_002446"
     CDS             complement(16467..16691)
                     /locus_tag="PC465_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2649732.1"
                     /translation="MTVYNLKLGQKGIIDNIAGNEKLMKRLLALGLIDGTEVEVKKIA
                     PLNDPIVIRFRGFDLAIRKSDAKNINLKNN"
     gene            complement(16788..18041)
                     /locus_tag="PC465_002447"
     CDS             complement(16788..18041)
                     /locus_tag="PC465_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:glutamate symporter"
                     /protein_id="HDF2649733.1"
                     /translation="MITLSFDIVQTLTLSIFFFLIGNLLNNKVNFLNNFCIPAPVIGG
                     LLFCFLNLFFKYFNIADISISGNLMPNFITFFFTTIGLEISINLIKKGGSVLFRYWIL
                     CGVLAFCQNILAITISKIIKLEPLLGLMCGNVSMEGGHGYSAAFGLTIENLGIEGAVG
                     VGLSAATIGLIMGGILGCPVAKFLINKYKLKPSSNIDLSIPRYNRNLKRFGSKFFRNK
                     NRIKNNNFSETITPSVFLEQVLLIFICINTGEIISRCFYITFNILLPSVVTCMFSAVI
                     FRNLNDKINILELNFKLIDFLKELSLGIFLTLSLMNIDLFELSTLLPPILLIVTFQVI
                     FIILFSIFICFRVLGKDFDSAIIISGLIGHGIGATPNALANMSSLTQKYGDSPKAFLV
                     VPLVSGFLLDAISIPCILFFINILT"
     gene            18301..19290
                     /locus_tag="PC465_002448"
     CDS             18301..19290
                     /locus_tag="PC465_002448"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HDF2649734.1"
                     /translation="MFENLPKIDLHCHLDGSVRVETMLDIAIKEKIDLPSNNMDEIKK
                     LAKVSFNCTSLDEYLEKFDLPLKVMQSKENLKRITFELLEDASRENVKYIEIRFAPLL
                     HTQKGMSVKNIIEGIIEGIREAESIYDIKGNLILGCMRTMTSKEALLVIEEGKSFVNK
                     GVVAVDLCGPEKEGFCKEYKDVFKLAREYGYKVTIHAGEAASGENVLDAINILKADRI
                     GHGVKIKDHKKAYNLVKDKKILLELCPTSNVQTKTVDSYEVHPFYTFYKDNLHVSINT
                     DNRTVSDINLSSELNVIFDTFKLGLEDYKIIYRNAVEASFADKETKEYLNSLI"
     gene            19362..20102
                     /locus_tag="PC465_002449"
     CDS             19362..20102
                     /locus_tag="PC465_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HDF2649735.1"
                     /translation="MKDYEDVVYIKLVKKELEEWKKNILKKPSIFDKASKGIQNKFNG
                     VLPDKYHEIITSSIKVMTKTVLFGYKYATKPPLRNMSLEEREKLVLEKAKTYKTTAMI
                     EGAGTGAGGILLGLSDFPLLLGIKVKFLYDVASIYGYDVKDYRERIYILNILQLAFSS
                     QQHINKTFKLMNNWDEYVNSLPEDINDFDWRTFQQEYRDYLDLAKFLQLMPGIGAFVG
                     FYVNGKLIDKLCETAVSAYRLRIRELKL"
     gene            20318..21469
                     /locus_tag="PC465_002450"
     CDS             20318..21469
                     /locus_tag="PC465_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HDF2649736.1"
                     /translation="MTNLPKQFDSFNEARQKGFINAKELKESGKKMVGVFCTFTPVEI
                     PMAAGATVVGVCGVSEEPIPDAERVLPRNLCPLIKSSYGHAITDTCPYFYFSDLLIGE
                     TTCDGKKKMYEELAKVKPTYVMHLPNTSKGEFAYKLWKDEMIRLKEEVEKSLGVTITE
                     EDIRTAIKDKNEERELLKEFYALGKLQPSALTGLELHNVLYQAGFKFDRAELKHSLRK
                     VIDDMKERYEKGECPVQKDKPRILITGSPIGGISEKIVKTLEDAGASVVAYELCGAIR
                     SNDLLVDEEIEDVYDALTQKYINIGCSCMMNNDNRIELLDRIIDEYNVDAVIDVVLQA
                     CHTFNIESYRIREFVTKEKNKPFMSLETDYSKSDTEQLRTRFEAFVEML"
     gene            21494..22249
                     /locus_tag="PC465_002451"
     CDS             21494..22249
                     /locus_tag="PC465_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyglutaryl-CoA dehydratase"
                     /protein_id="HDF2649737.1"
                     /translation="MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKSTSKQVYE
                     LLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITCHTRGIYFLNNNIRTILDVGGQD
                     SKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSM
                     CTVFAESEIVSLLAQNISTGEVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKE
                     LVKMIEEILGKKIFIAEDTQIIGALGAAVIGFR"
     gene            22441..24828
                     /locus_tag="PC465_002452"
     CDS             22441..24828
                     /locus_tag="PC465_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp13"
                     /protein_id="HDF2649738.1"
                     /translation="MKKFTSKKVTRFVALFLISILVMSTIPVSADNSNTLNQIKKAEY
                     SETYKQYLNDAKNGRTEKYNGIIPNPYQLEGTQIQSKGRTAPTSYDPRKLGLMTSIKN
                     QEDLGICWDFAAMATLESFLKLNNYGDYDLSEEHLRWWASDGEYGWSVNDMNGALNYE
                     AMGYLTSWSGPKLEKDIPYNGRVSKAQGAKKPTNMNTAPTVFNVTDAVCVSNDINSTK
                     NAILQYGAVTSGYYEDIKYQSDDQNSYYCPTKSFNTNHAISIVGWDDNYSKDNFNSNI
                     RPSKNGAWLIKNSWGDYNSEGGYFWISYEDKTLMSDIDNFSIKGGKKPNDDEKMYQHD
                     YASIVPLISKKITAANVFDFNRGDETLKSVMFLTESIGAKYEVYYAPVVNGIPQENNM
                     KKLKEGTAQYSGYITVPIDSFDIPEGKGAIVVSIEGKNGESTIGSESNVPGYDTFKAK
                     ANLGESYIIDNTGKFFDINRDSNFYPCNFTIKAVTEKSSGESIPNESLIGSDRYETAI
                     KVSQNGFNSSENVVLVNGSSIVDALAATPFTSAINSPILLTQKEALNSKTKAEIQRLG
                     AKKVYLIGGENSISKEIEQQLKSLNISIERISGSDRYKTSLLLAQKLNGIKNVSQIAV
                     VNGVKGLADAISVGAAAAENNIPIILANEKSELQGADEFLNSLNIEKSYIIGGTASLS
                     NNLESKLKNPTRLSGSSRDETNSKIIDNFYKKDTLKNAFVVKNGIKNQNDLIDGLAVG
                     PLGAKTGSPVILVGDKLADSQKEVLKNKTLEKVTQVGGGANKNAFKELVKLKSAK"
     gene            complement(25059..25292)
                     /locus_tag="PC465_002453"
     CDS             complement(25059..25292)
                     /locus_tag="PC465_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDF2649739.1"
                     /translation="MATTTKNRFYDYVQENLNKYVEVHSYFSSCPLYGEIIEADSLSI
                     TLCSRYIDESNPTLNETYTLYLPLSSIISIRTL"
     gene            25581..26171
                     /locus_tag="PC465_002454"
     CDS             25581..26171
                     /locus_tag="PC465_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2649740.1"
                     /translation="MPKSYSDKEREYIIKRLKEEARLCMEQYGIRKTTVDELVKRVKI
                     PKGTFYLFFQSKELLFFEVLRDIHDSIQKEILYEINRVDESITCEQLTDIFMKFYRMV
                     DSTSILNLMINGEFEILVRKLPDSIIEEHFRHDDFEIGEIISCIPNAKNKDIESFSGA
                     FRAVFLTMLYKREVGSNCFEDALRLMINGLVIQLME"
     gene            26285..27130
                     /locus_tag="PC465_002455"
     CDS             26285..27130
                     /locus_tag="PC465_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2649741.1"
                     /translation="MIKVDDLSFSYTDRDFLQNINFGVGKGEILGFLGPSGAGKSTLQ
                     KILIGMITNYGGSVIVNGVESKRHSNKFYENIGVDFEFPSLYEKLTAIENLKYFGSLY
                     SKKLLSIDELLKSVGLENEANKRVSEYSKGMKSRLNFIKALLHNPDILFLDEPTSGLD
                     PSNSKVMKDIILSEKLKGKTIILTTHNMLDATELCDRVAFIVNGKISALDTPHNLIMS
                     KGAIKVRYTYFDNGEKTAECFLNNTANDKNLNMLIEKNKLLSIHSSEPTLNDIFIEIT
                     GRNLQ"
     gene            27127..27810
                     /locus_tag="PC465_002456"
     CDS             27127..27810
                     /locus_tag="PC465_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2649742.1"
                     /translation="MRLKNLILGDIKFQFKYGFYFLYLFLSIIYICIINVFPTFMREK
                     IVIIMIYSDPAAMGLFFMGAIVLLEKSQRVLNSLAVSPVKVSEYILSKVISLGVISSI
                     VAMFIAITLNLDNIIISTIGTFFSSIIFSLLGLILASKASSLNQFIVLSIPIEIICFI
                     PPILNVLLDTKSYANLYPFNICISLISGDKNFIMINILILISIIIIIYFITYYFICSS
                     WKKVGGVKL"
     gene            27807..28523
                     /locus_tag="PC465_002457"
     CDS             27807..28523
                     /locus_tag="PC465_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2649743.1"
                     /translation="MIKIINAFKQEFEQIKRDAMLFIVCVSPILCGVFIKFGIPLIQN
                     ISLNKFYYQLNLEPYFLMFDLLLAFITPFMFFFASTMVILGEIDDSISRYLIVTPLGK
                     TGYLISRFGIPGILAFIITMILLIFFSLTKISFLLNLSISLLVLLQGIIISILVISLS
                     SNKLEGMVITKFSGVFMLGILAPFFILNKAQYILFFLPTFWISKAFKEDNYIYMFISI
                     VISLIWILLLFKKFSKKIVK"
     gene            28620..28883
                     /locus_tag="PC465_002458"
     CDS             28620..28883
                     /locus_tag="PC465_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2649744.1"
                     /translation="MKNKIKILREKLGLTQEQLGRLVGTSRQAINAIETGKNEPSIWL
                     AYDISRIFNEPIESVFLFEESERKSRAQISRGEYYGYKKDKNI"
     gene            28855..29310
                     /gene="def"
                     /locus_tag="PC465_002459"
     CDS             28855..29310
                     /gene="def"
                     /locus_tag="PC465_002459"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDF2649745.1"
                     /translation="MAIRKIRTFDDEILRKKSKYVENVDNKIREILNDMAETMYNTPN
                     GGGLAACQVGVLKRLVVIDLGEGLIKLVNPEIIKQEGEQIVVEGCLSFPEVWGKLKRP
                     KKVTVQALNEYGEKIEIKGSGFMAKCLCHEIDHLNGIVFTDKIIEHVKL"
     gene            29362..29823
                     /locus_tag="PC465_002460"
     CDS             29362..29823
                     /locus_tag="PC465_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine dimer DNA glycosylase/endonuclease V"
                     /protein_id="HDF2649746.1"
                     /translation="MRLWHKDLIDVLPKNQLVSQWRELLAIKGSIDKKGTPNHLLVNK
                     VLNYSIDEFKFYTKIVHDEMLKRNYKPNELKYTSILKWKNRNFANDISNEHSLNLENL
                     YDDWHNKMYLKQCLYNLEEKATCGGIPINEWNILLCKYSKDYELWSGNIMF"
     gene            29873..30775
                     /locus_tag="PC465_002461"
     CDS             29873..30775
                     /locus_tag="PC465_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2649747.1"
                     /translation="MYNKIKYIPINCEIACNKLKRSMPYKWDLNIYRGCEHGCKYCYA
                     IYSHKYINSNNYFEEIYVKTNIVEKLERQLKSSKWKKEVINIGGVTDSYQPIEADYKI
                     MPEILNLLIKYKTPAIISTKSDLILRDYDLIDKLSRITYINVASTITTVNEDTQRLIE
                     PNGVDSMRRFKMLKEFRKTNASVGLHIMPIIPYITDDFDNINSLFRHAKECNVHYVLP
                     GTLYLRGITRGVFFDFVKKEFPELFDKLSILYSAGSLNREYKNQLYKMVNELRYKYSL
                     SSSYSKIMKEKLKNSGDVQISFFD"
BASE COUNT        12304 a         3172 c         5130 g        10200 t
ORIGIN      
        1 tttataagtt taactataaa ttaggtttat attttataaa aatttgctaa aaaaaacaat
       61 taaaaattgt aaagaaaaaa gatataatta gaactgtagt aataaatgtt ttattataga
      121 taatagagtt ttaagtatct taaataatat ttggaggaat atgaatggaa ttaagaccaa
      181 gaagtgcaaa attagaagaa tttgataaag taatagaatt aataaactat gtatttagaa
      241 tatcaagaaa tcataaacca actatgatgg aagaatttcc tcttttacta agtaaaaata
      301 atatagaaaa tatgattata atatcagaag atgataaagt ggtttctgat gtaaactatc
      361 taattcagga tgtatctatt caaggaaaca gattgaaggt tgcagctata ggtggagtat
      421 gtactcatcc agattatgaa aagagaggct attcatctaa gatattggat aaagtagaag
      481 aaaaaatgtt ttatgatggt gtagatattg taattatatc aggaacaaga agtctataca
      541 gtagaagaaa ttgtagtttg gtaaagagtt tttataaata tacaataaaa cctgaagatg
      601 taaaaatagc atatgaaata gttgaatttg atgaaactaa ttttgaaaaa gataatgatt
      661 tagataaaat gattgaacta tataatcaaa atagtactag atttataaga acgagagatg
      721 agtttcaaaa actattgcat gcagcaacta ttgcctgggg accaattggt tacaagaagg
      781 tatttataaa ggaaaataat aatataatag gatatttgat aataagaaca ataaaaaaag
      841 aagattctac tgtaggagaa gttgctgaaa tagggttaaa ctctgtaaat gttgaaaata
      901 tattgaaata tgttgcaaat aaatttggat tagaatattt aaattataaa gtacatgtga
      961 aaaatcttaa agaccagttg aaatgtaatg ggacaaaatc tttggattat caacaaggaa
     1021 ctatgaaaat aataaatttt actaagttgt gtgatagttt aagaagttat tttagtcaat
     1081 atgtagattt tgaattacta aaatacatgg aatttaaaca agttgaaaat aaatatatta
     1141 ttaaatacaa agaagaagaa cttgtaatag aaaatttgga taagcttaat aaactgtttt
     1201 ttgaaaaaaa tgaggaacag tacaatgact ttaaacatct aaaaaatata tatgaatttg
     1261 ctacaaaggc atttcctgta gattttccat ggactgcaaa tttaaattat caatagtttt
     1321 agatgatatt aaataaaatt gattgatacc tagagttagt ccttgttaaa taagagaaat
     1381 tattggatat tgaaaaagca attttgtaag taattagaaa ggatgagtat tatatggaca
     1441 tacttgatga tatagcagaa tgtatattaa atatgggtgt agataatata gagaatttag
     1501 taaaaattgc tatagataaa aatattgatg tggaagatat ttatgaatat ggtttaaaca
     1561 aaggtatgat aggagcttta gataagtttg agaataagga atactatctt tcagaagtta
     1621 tagtatgcac agatgcatta aataaaggta ttaatctttt gaagggaact ggaaaagtaa
     1681 agaaaaaatc aaagggagta attctgatgt ctgtagtaga aggagatact catgagatag
     1741 gaaaaaatat tgtaaaagta atggtagaag ccactggata taaggttatt gacttaggtg
     1801 taaatagaaa aagtgaagat ataatagaag aagctataaa aaacaatgta gatataatag
     1861 gcttatcttc aatgatgaca actacaatgg aaaatatgaa atcggttata gacgaactta
     1921 atatgattga gatagataaa agaccaaaag taataattgg tggaggacct gtaagtatgg
     1981 agtttgcaga agaaatagga gcagatggat acagttcaaa tgctccaaaa gcagttaaat
     2041 taataaataa acttatagga ggtgaagttt aaatgttttc agatatgact ttacttcagt
     2101 atataaatag tgaagataga ggtttttttc tgcctgatat gggtacaaat ggattgttct
     2161 taataaataa aaaggcatat gaagtatatg atagtgtaga tttgcaatta gaattagcaa
     2221 agactatgga caagtatttt gaatcagatt ttatatactc attctgtgat gggattacat
     2281 tttgtgaaac tctgggttta gagacattaa gaccagatta tgattttcca agtgtattga
     2341 cacatactat aactgacaga gataaattaa gaaaattaga tgttccagac ccttatacga
     2401 gtggacgtat gccactcaat atagagagct tatcagttat atcaaaaagt attaaaaaac
     2461 cactatatga atcgatacaa ggtccattta cacttgcagg tcaattagct ggagctactc
     2521 aacttttaag atgtataata actgataaaa aatttgtaga agaattattg gaatttacaa
     2581 ctgaattggt aagaagatat gctgtagctg caaataaagc aggagcaaaa tatatttcaa
     2641 tagcagagcc aacatcagta accctaagta aagatagatt tgatgaattt atagtaaaaa
     2701 atttaaataa aatctacaat gaacttgatt gttggaaagg tatgcatata tgtggagaca
     2761 ccagagaatt attagataat atgctaagtt gtaatataga tgcagtaagt ttagaccaaa
     2821 ttttagacta tgaagaaatt gctccaatga ttcctagaga tatagttttg attggtaatt
     2881 tagacccaat aaaacttctt ggacgttcta agccagataa gattagaaga gagacactaa
     2941 aattgttaaa gaagatgaga ggatatgata actttttatg tgattttggc tgtaactgct
     3001 taaataccac tccagtagaa aatttacaag cagctataaa ggcaggaaga attagttata
     3061 aagaattaga taggattgat attgatgaat tataatagta ataaaaataa atatctttta
     3121 aaggatataa atttagatga tatttttata gataagaata ttgtgctaaa gtttttgggg
     3181 tatggaaata gaaaagctcc agatacaatt agtaaaatcg ttgaaagaga aataagaaat
     3241 ataaatgata ttttagatat caagatatat ataagtgaag ttgatattaa taaaacacct
     3301 aaagaatgta aaaaagcatt tgctgtacta tatacaatag gggataaaat tgatattaag
     3361 atgaatgact atatggaaaa ttgcaatatg atggcagggc tagcattgga taaaataggt
     3421 atagtatgtt tagattgtat taatgagaaa ataaaaatgt atttaaaagg aaagtatgat
     3481 agtctcaaaa tatcgcatga aatatatcca ggagataaag attttgaagt agagagacaa
     3541 aaggatattt ataactatgt aaaaaataaa tataatagta tagaaataga aatcaatgat
     3601 tatcatcaac tatcccccat aaaaagtgtt gcaatgctta ttttaatggg ggatgaagaa
     3661 aatttagaat caagatgtag caaatgtcct agaaaatgct tttaactagt tttcaagact
     3721 aagatttgtt ttgtgtatga attgcaataa tttttttggt cattttatgt ataaactaaa
     3781 aaaattattg caaagtaata ttctatttaa tttgaacaga cttacaaact atagtagttt
     3841 ctttaattca ataagtgtat ttatttcata agttggtata tgattagtat aatttatact
     3901 gttattggaa tttaaccaac aagtatctat tcctgaattt attccaccta agacatcaga
     3961 ggttaagcta tccccaatca ttaaggcaga agatttatca tgacaattaa actttttgag
     4021 agcgtattta aatatttcag gatttggttt tgatattttc aactcttcag atacaaccat
     4081 tccatcaata tattctttta tttttgaatt ttcaagtctt ttcttttgaa ctgcagaaat
     4141 tccatttgtt attataacaa tagtatactt ttttttaaga tattgtaata tatcgattgc
     4201 acctggaatt aaaaatgtac attcacctaa aaaatttaag tacattttgc taagagtttc
     4261 agaatcaaca tccaaagata ttttatttgc aaaaagttca aatctaagta atttaagttc
     4321 attcaaagtt ataatatttt tttcaaggtc gagccaaagc ttatcactta tatttctata
     4381 tgactctata taattctcaa aattaaattc taaatcaaac tcagatagaa gttttttaaa
     4441 agcatgtgat tcacttttct taaaatcaaa taaagtatca tctgcatcaa aaaatataaa
     4501 tttatatgtc ttcatggttt ttactccttt acaagatgac tgcaaaaatt actttacttt
     4561 cactatttga gtcattttgc catttatgtt ttgttcctaa aggaactttt acactatctc
     4621 ctttggacaa agtaaattca tcatcatcca taaaaagttt aacttctccc tccaaaacat
     4681 atgcaatttc atctccatta tgagtaatcc tatcaacaca agaagaagtg tttggagcta
     4741 aatccataat tgcaaattct aaattaccac tagagtctgg aattaaaatc tcatatataa
     4801 cttctttgct tccaggtaaa ataacttttt ttctattatc atgtcttact atcaagtttt
     4861 ttttatctac ttcagataca aaaaatgtaa ataaaggaac atttagagaa gaggctatag
     4921 attttaatga atttacagat ggattagcaa gacctcgttc tatttggctc aataatgatg
     4981 gtgtaacatc agctagtttt gctaaatctc gaatacttaa gttttgtttt tttcgaactt
     5041 cagctatttt ttcccctaaa tttaaatcat tcatataaat atcctctctt tttaatttaa
     5101 aaaatattaa cttaaaataa tcaagtaaaa tgattatgta gtatgaaatt attataacat
     5161 atagaattag gttttgaaaa aactatgttc aatataatta aataaattaa aatataattg
     5221 acaaagtgga tacagaatac ttaaaatata tttaaataaa attaagcaaa agatagttaa
     5281 tttatgatag gaggggatat tatgcaaata acgacttttg gagctatatt tggtttatta
     5341 atagcaatta ttttaattat aaaaaaattt caagctgtat atagtttaat gttaggagca
     5401 tttattggag gattagttgg aggagcaaat ataacacaaa ctgtagattt tatggcaaat
     5461 ggagctatga atatatcacc atcaattctt agagctttgg catcaggtgt attagctgga
     5521 agtttaataa aaacaggggc agtagataaa atatcagaac agattgtaaa aatatttggt
     5581 gaaaagaggg ctttattttc gattgccatt tcaactatgg tacttgctgg agtaggcgta
     5641 aatttggatg tatctataat aactgtagca cctataggat tatatatagg tagaaaatta
     5701 aattattcta aattgtcaat actattagct atgttgggag ggggtaaagc aggtaatata
     5761 atatcaccaa atccaaatac tatagcagta gcagataatt tttctgtcaa tctctctagt
     5821 gttatgatgg caaatataat tccagcaatt attggagttg ttattacagt tattttagca
     5881 agtatattaa taaataaagg aaataaagta caatcatatg aaattttaga gcaaagagaa
     5941 gatttaccaa gtttatttaa atcattatgt ggtccaatta tagctatatt tctattgttt
     6001 ttaggaaatg tatctcctat agttatagac ccaatgatag cccttccaat aggaggaatc
     6061 gtaactctaa ttgtcacagg aaacttgaac aattcaagag aatatttagc ttttggatta
     6121 tctaagatgc aaggggtatg catattatta cttggaacag ggactatcgc aggaattata
     6181 cagatgtctg aattacaaca gagtacaata ggtgctttac aatttttaaa tatgccacaa
     6241 tttttattgg caccagtttc gggtatactt atgtcattag caacagcatc atcaacagct
     6301 ggtgctacta tagcatcatc tacttttcat gatgctataa taaatggtgg gctatcaccg
     6361 atttcaggtg catcaatagt aaatgctggg tctagtgtat tcgagcaatt accgcatggc
     6421 tcactatttc atactagttc aggtagtata aacatggata taggtgaaag atttaagtta
     6481 attccatatg aagcattgat aggaatagta atgactataa tttcaacatc tattcaatta
     6541 gttttataat aaatataaat atttaatgaa aaaagtagga ttttgttatt aaatattgaa
     6601 tttattatag taaaaaagaa gattggagtt ttaaagtgaa taaaaaaaag attgttatta
     6661 tagggattat ttattcattt ttagtagtat tttcacttac aaatatgtat gtaaatatgg
     6721 agtataattt aaatgtattt gaatatatta agaagtcact tccatttaca gaagaagaaa
     6781 aaaagtggtt agaaaaacac aagaatttga tttacagctc tgaccaaagt tcacctcctt
     6841 tgagatataa aggtaaggaa gatggacagt ataagggaat tattgttgat ttaataaatt
     6901 ctctgtcaat tcaaattggt agagattttt attttaaacc aaataattgg tggaaagaat
     6961 ctttcgtaaa ttcaatagat gatagtataa agttttttga cttgattcca tcaaaagaaa
     7021 gggcaaataa atttatattt actgacccaa tatacacttt gagtgcaaat atattgaaag
     7081 ataaaaagtc ccaggatata aatagttaca tggatttaaa ggggaaaaca gtagcaattc
     7141 cagaaggtga ttattctata aattttttaa agcaaaaaat tcaagatata aacattttat
     7201 tgactccaga tataaagact ggagtcaacc atttaatgtc tggaaaagta gacgcagttg
     7261 ttggtgatga accagtattg cgatactata taaataatta tggactttca aataaataca
     7321 gtgttttaag taatcctata tatactaaaa aagcagttct tgctgtacct aaacaatatg
     7381 aagagctggt tagtatttta aataaaggca tttttaaact tcagaaaaat ggagtgtata
     7441 aagatttaaa gaaaaaatgg tattctacgt ataatgaagt tgatgatata ttgtatgagc
     7501 gaggaattgt gcctagtatt tatcttttta taggtataat tttaatatca atttatgttt
     7561 tttatagcta tacatatttg ttaaagatag aaatcaaaag gaaaacagaa caggtaatag
     7621 aaaataaaaa aactttagag gcaactttta atagtattac agatataata atgcttgtag
     7681 atgaaaataa caatatagta gaatcgaaca aagtactata tgactttatg ggtgaaatga
     7741 gttataagat agcagatttg attagcatga taaaaggtgt tattgaaaat accttctctg
     7801 aaaatactaa taaaactagt gaaatagaaa tacacaataa aattttaaag ataaacactt
     7861 ttcctgtaga gtataaaaaa aataatactg agtatatagt agttcttatt aaagatataa
     7921 ctaatgataa aatagtagag gcgaaattac ttagagaaaa caaaatgata tctataggac
     7981 aattagcttc tggggtagca catgagataa gaaatccttt gggtataata agaaataatt
     8041 gctatctctt aaaagataac gttacaatgg aagaagtaaa tgattgtgtt aaatcaatag
     8101 aaagtaatgt agatagagca agtaatataa taaccaactt gttaaatttc gcaagaatat
     8161 cagatgataa tttagaacat ataaatataa gaaattttat tgaaaatata gtgaaacttc
     8221 aatataaaat gttacagtta aagaatgttg aaataaaaat tgactgtgaa cataatttaa
     8281 tatgctatat aaatggagaa tcgttaaaac atgtatttat aaatttaatt tctaattcaa
     8341 tagatgcaat acatcaagat ggaaaaatta ttatatactg ttatgaaaaa aatcattgtt
     8401 tatttataga ttttaaagat aatggtgaag gaataaaaga agatgcccta aaggacatat
     8461 ttaatccctt ctatacaaca aaaccaattg gtgagggaac tggtttaggt ttatacatta
     8521 cttataatga gattaaaaag aataatggag atataagtgt tgaaagtaaa ttgggggttg
     8581 gaacttgttt tcatataaaa attccattaa ataaagaggt gactatataa tgaaaatact
     8641 attagttgat gatgagctag aatatggagt ggtaatgaaa aaaattctac aaaagaaggg
     8701 ctatcttgta gatatagcac taagtggtga agaagctata aatataatta aaaaagataa
     8761 aaattatgat ttggttttat ctgatgttat gatgaaaaat atggatggag tacagctatt
     8821 agatagaatt aaatctatta atagagatat agaggttata ttagttacag gatatggaag
     8881 tattgaaaat gcagttgatg ctatgaaaag aggagcttta tcttatttta taaaaagtaa
     8941 tcccattgaa aatttattag aagaagttga aaaggtaaag gcaagtaaaa tatctgtttc
     9001 tgtacaaaaa aataatttgg aatttacttt ggaatctaaa aatagagatt ttaataatat
     9061 cataaaaata gcaaaaaaag ctgcttgtaa agatgttaat atattaatct tgggagaatc
     9121 tggtgtagga aaagatatat tagctagata tatacatagc ataagtccaa gaaagaatga
     9181 gatatttgta cctgtaaatt gttgttcttt ttcagaaaat ctattggagt ctgagttgtt
     9241 tggtcatgaa aaaggttctt ttacaggagc agtagatagt agaaaaggta gatttgaact
     9301 ttcgaataaa ggaactctat ttttggatga aataggagat atacctctaa atgttcaggt
     9361 aaaacttttg aggacacttg aggacaaatc tatagagagg ataggaagta ataaatctat
     9421 taaagttgac tttaggttaa tttgtgctat gaataaagaa ccaaaagtgg aaatatcaaa
     9481 tggaaatata agagaagatt ttttttatag aataagtaca ataacaataa ctataccacc
     9541 gctaagaaag agaagagaag acttaactac tcttatagaa tttttcttaa ataagtacca
     9601 aattgaacat gataaaaaga tacactcgat tgataaggaa gtaaaggatt ttttattaaa
     9661 ttacaattat ccaggaaata taagagaatt aaaaaatata ataaatagac ttgtagtttt
     9721 aagtgaagaa ggcaatttat caaaagacaa tttaaattta atatcaaata atgtatacat
     9781 agatgataaa ataagtatta gacctttaag agaaataaga aaagagtttg aatgtgagta
     9841 tattgaaaaa gttttatctt tgtgtggaaa taatatttca aatacagcta aaaaattgga
     9901 gattagtaga agacagttaa ccaataaaat atcagagtat aatattaagt gagaaaaaaa
     9961 cttctcatta agtgagaaaa aaatttctca aactgtatta aaagataaac agaaaaaatc
    10021 tgtttatctt tttttattat aattttaaaa attaatattt acaataatta ttggtaaatt
    10081 caatattggt gtaaattaaa aatgaaaatt tctatgacat taatacatag aatatatatt
    10141 ttaaataatt ggcatagaaa atgctttata tattaataaa cgtaataaat acttttaatt
    10201 gcgattaaat atattaaggg ggattttcat atgaagctag agctagggaa tatatttata
    10261 aaaaatgttg aatttggaga aaagacagaa gtaaaagatg gagtactata tattagtagc
    10321 gaagaaatag aaaagatagt attagaagat gaaaggattg taagtgtaaa tgttgaactt
    10381 gcaagacctg gcgaatcaat aagaatagct ccagttaaag atgtaataga gcctagagtt
    10441 aaaattggag atgaaagcaa aatatttcct ggaattataa ataaagtgaa gactgtagga
    10501 agtggaagaa cccatgtact tttaggagct tgtgttgtaa cttgtggaaa tatagttgga
    10561 tttcaagaag gcgtaattga tatgagtggt cctactgcta aatatacacc tttttcaaaa
    10621 acaaataata tatgtattgt tataaaagca aaggatggta tagatactca tgattatgaa
    10681 gaagcagcta gaattgcagg attaaaaata ggtgcatatg taggtgaggc aggaagagaa
    10741 gttgagccag atgaagtcat tgtatatgag acaaagccat tattaaaaca agtaaaagaa
    10801 tatccagacc tgccaacagt agcatatgtt cacatgttac aatcacaagg acttttacat
    10861 gacacttatt actatggggt ggatgctaaa cagatagtgc ctacatttat gtatccaact
    10921 gaaataatgg acggagctat aatatctgga aactgtgtag caccatgtga taaggttaca
    10981 acattccatc atttaaataa tccagttata catgacttat ataaaagaca tggaaaagat
    11041 ttaaacttta taggagttat tttgactaat gagaacgtat tcttagtcga taaagagaga
    11101 agctctgata tggtagctaa attaatagaa tttttaggag ttgatggagt tctagtgaca
    11161 gaagaaggtt atgggaatcc agatactgac ctaatgatga attgtagaaa atgtagtgaa
    11221 gttggagcaa atgtagtttt gataacggat gaatttcctg gaaaagatgg caagagtcaa
    11281 tctatagcag acgctactaa ggaagcagat gcagttgttt cttgtggtca aggaaatcta
    11341 gtggttcatt tcccagcaat ggaaaaaatt ataggaactt tagattatgt tgaaatgatg
    11401 ataggtgggt ataaaggatg cttaaatgaa gacggaagca tggatgcaga gctacaaatt
    11461 ataatagcat caactatagc aaatggctat aatcatttga cagcaagata ttattaaata
    11521 agtatttgaa tataaagttc tgttgatgta atcattggtc taactgatgt aataactata
    11581 aagtgatttg gaggattaag agatgagtaa aatcagagtg gttcattata taaacaattt
    11641 ctttgctggt ataggtggag aggaaaaagc agatattccg ccagaaaaaa gggctggtgt
    11701 agtaggacct ggaatagcat ttcagagtca atttaatgat ggtgcagaga taatctcaac
    11761 tgtaatttgc ggagatacgt attttggtga aaatattgag agtgcaactc aagaactttt
    11821 aaaaatgata aaagaagaaa gccctgattt atttattgca ggcccagcat ttaatgcagg
    11881 tagatatgga gtagcttgtg ggactatttg taaggcagtt gaagaagagt taaatattcc
    11941 tgtaattaca ggcatgtata aagaaaatcc aggtgtagat atgtttaaat tagatttgca
    12001 tatagtgtct acaggaaatt cagcagcaag tcttagaaag gtagttccaa taatgacgaa
    12061 actaggtctt aaattggtta gagatgagga aataggacct cctgaagagg aaggatatat
    12121 aatgagagga ataagaaaaa atttcttcca tgaacttaga gggtctgaaa gagcaattga
    12181 tatgttggtt aaaaagatga aaggggaaag ctttgaaact gagtatccaa tgcctgaatt
    12241 tgatagagtt acacctatga aacctgttaa agatttatct aagataaaac ttgccctagt
    12301 aacttctgga gggatagttc caattgataa tccagacaaa attgaatctt caagtgctac
    12361 taaatatgga atttacgatt taacagatat ggattctatg tcaaataaag aatttacaac
    12421 tatacatggg gggtatgata gagcatatgt ccttgaaaat ccaaatttag ttgtaccact
    12481 agatgtagtt agagagcttg aaaaagaagg tgtaattgga gaattagtag attattttat
    12541 aactactaca ggaacaggaa cgagtgttgg caattctaag agatttggag aagagttttc
    12601 taaaaaattg ttagaagatg atgtagatgc tgtaatttta acttctacat gaggtacttg
    12661 tactcgttgt ggagcaacga tggtaaaaga gattgagaga gctggtatag cagttgttca
    12721 tatatgtaca gtagtaccaa tatcacttac aataggagct aatagaattg ttccagcagt
    12781 agggatacca tatccacttg gaaatcctat gttaggagaa gaggaaagta aaaaaattag
    12841 aaagaatata gttttaaaag ctttaaatgc actaacagaa gatatagaag aacaaacagt
    12901 atttgaataa taaaaataca acacaacact gaaataaaaa aagatatcaa aaaataattt
    12961 tttaaaatta ttttacgata tcttttttta ttaggtaaat tcgaaagttg catattattt
    13021 gcatattttt aaattaaatt tataaaagtg ataaattagt ttattataat attgatacac
    13081 aaattcaaat tagatatact atgaaaagtg agattattac attttggaac aaatattcaa
    13141 catattaaac cagattaatt gaacagaaaa aattaacttt atataataat tagaataatg
    13201 ataagaaaga aggtgtatat attgatttca attgccattt gtgatgatga atcctatatg
    13261 ctaaatcatt taaaggaaaa tatagaatta tacatgaagc agaagaattt attatataat
    13321 atagagcttt ttaataaagt agaagattta ctatgcaatc atgaaaagtt taatattgta
    13381 tttttagata tacagatgga agagattaac ggaatgcagg cagctagaaa attaaggtca
    13441 tatggtaatg agtgctttat aattttcgtt acagttttaa atgaatttgt atttgatgct
    13501 tttgaagtag atgctataaa ttatttgata aaacctctat ctaatgagaa actatataaa
    13561 actttggata aaatagttac aaaactcgag gataatgaaa gtaattatat cacaatacaa
    13621 aaaggttatt catattggaa attaaaactt gctgatattt tatattgtga agttataaaa
    13681 agaaagattt atgttcattt aaagaaagag actgtagatt attatgagac tattgaaaat
    13741 ttagagagaa gtttaccaac aaattttttt aggtgtcatc gtagttatat aatcaattta
    13801 caatatgtat atggatatga aaatggtaat gcagttatgg aaagtggaga tagaatacct
    13861 gtttctagac tacgtcaaca aatattttca aaagttatgc ttgagttcat gaaaaatagg
    13921 aggatataag atgattaatt tattttcttc cgatttattt ttaaagtaca gttttttatt
    13981 ttcttttatt gtatatagaa ttttaatggt aatagtgcaa tactattttc taatcagttt
    14041 tacaaatgtt aattcaaaat tttggtgttt tattttatat tcgataattt caattttttt
    14101 aatcattata aatacatatt ttaatttata taatttattt tcttcacaga ttctattttt
    14161 tcttatgact tttttatttg taaagtacat aataaaacaa tctactgttt tatctatagt
    14221 atcaactttg ttagtatatt taattgaaca attagtatat ggatttacag ctccattaaa
    14281 ttacttgata tttactagtg atataaatac agatatttat aaatttgata taaatatggg
    14341 actatcttct ttaattacta ttataatagc tggatttata tattggtata gttctaaaaa
    14401 gtttaatatt aaggtcatga actttgataa atatatagca attttgatga ttccattgtt
    14461 gcttataata ttatttatgc aatcatttga atatagttca aatataaata tagatacaag
    14521 tcttgggatt gtaaagctgc tattaaatac ttctataact gaagaaattc aagcttttct
    14581 tttttctata attggaacta tatgtgtatt tttttctcta tttaccttta agaaactaat
    14641 tcaagctctc gaagatgaca aggagagggc aattatgaat caacagattc atgctcaaaa
    14701 aaactatatt gaagaagcga aatcacgatt atcacaaact atatccttta gacatgattt
    14761 taataatcat ttagctattg tcaatggatt gttgaaaaaa gaccaaattt taaaagcaca
    14821 agattattta aataagcttg aaaaagtaac aagtgaccta tcattttctt gtaatacaca
    14881 gaatattgtt attgatgctc ttttcaacaa taaattaagt atagcaaaac aattaggcat
    14941 agaggtagat tgtgaagtaa ttatacccca aagcactaac atgaacgatt ttgacctatg
    15001 tatagtgttt gctaatgcta ttgacaatgc aattaaagct tgtagagttg tagataaaca
    15061 aaataggtat ttaaagcttt ccactaagtt agaaggtgga ttttttatga tagaaataaa
    15121 aaatagctat aatccaataa ataattatac acgtggttca ggtataggtc ttttaaatat
    15181 aaaagaaatt gctaaaaaat atcaaggggc tataagtata gataagacat cagattattt
    15241 tcaaataaat gtattgctgg ttatttcatt acattgcgct agtatttgag aacaatttca
    15301 ttgaaaatag tatttgtaag ctatattatg tatttgaata gagaaagttt gatatataga
    15361 aatgaggagg ttactaaaat gaaagttgga aatataaatg gtcaagcacc aattacaaat
    15421 ggtttagata gttgtcaaag tgaggtacaa ggcttagaac aaaggaaaaa atcattacag
    15481 gatgaaatag agaaagtaag aagtgataaa agtattgatg gtgaaacagc caaattaaaa
    15541 atagaagctt taaaaaaaga aatggaagag attgaaaata aaattcaaga gttaaaagga
    15601 aataaagcaa aaaaaacaaa taaagaagaa aataatgttt cagaagtaaa taataatcta
    15661 ttagagagaa aaaaagaacc ttctaataat gaaaatgtaa aacaactata tgatgttttt
    15721 gaaagaagca atgtagacga acaatgggat aatacttatc gtgttctcca agatgataaa
    15781 aacttaaaag taaaatttaa tagacctata tagtttattt ataaaaatag ttaatatttt
    15841 aattatcacc actttttaga agaatacaca ctttatttta aagacccaca tatttattta
    15901 cagttagcac atttatatgt ggttttataa ctattattta caagtctata ttgataactt
    15961 ttacatagta tataatgttt aaatacttat tcaattttat ctatacataa acaaaaaaag
    16021 agattttaaa atctcttttt agattgttga cttatggctt tttgatttaa taaaatcaag
    16081 aagccgtttg aattttatat gttggttgat acccttctga tattgaaaca ccatttttgt
    16141 ttccaaaatc gtttaaaatt aagaacttat tatgaatgac tatttcatta tgaacaataa
    16201 gcagataaca tgaatcttca atcaatgttt taacagtagc attaaatgct tgcttataca
    16261 gttctatcgt ttgtttgaac tgtccattaa agtaaatatg agtcaataac ataactatat
    16321 ctacataaat taatataaat tttttatact gtacattatc taactgttga ttatctgtat
    16381 tacaacatga ttgaatttaa aaagccatca acacatagaa tgttgatggc ctgaaaatag
    16441 atttaaaatc tcttttttat tatatattaa ttatttttta aatttatatt ttttgcatca
    16501 gattttctaa tagctaagtc aaaccctcta aatctaatca ctatagggtc attaagagga
    16561 gctatctttt tcacttcaac ttcagtgcca tctattagtc ctaaggctag aagtctcttc
    16621 ataagttttt catttccagc tatattgtct ataattccct tttgtccaag ttttaagttg
    16681 taaacagtca ttattaacac ctcctaatga aaatcattat caaactttat atttataata
    16741 tataacaaaa agagcaaatt gtcaatatat aacaaaaaat aaacatacta agttagtatg
    16801 tttataaaaa atagtataca tgggatacta atagcatcta gcaaaaaacc acttactaat
    16861 ggtacaacca aaaaggcttt tggagaatca ccatattttt gtgtcaaaga actcatattt
    16921 gccaaagcgt tcggagtagc tcctattcca tgtccaatca aaccacttat tatgatggca
    16981 gaatcaaaat cttttccaag tactctaaag caaataaata ttgaaaatag gattataaag
    17041 attacttgaa aagttactat taagagaata ggaggtaata atgtagataa ttcaaataaa
    17101 tctatattca taagtgataa agttaaaaaa attcccaatg aaagttcttt taaaaaatct
    17161 ataagtttaa aatttaattc tagtatattt atcttatcat ttaaatttct aaaaataaca
    17221 gccgaaaaca tacaagttac aacagagggt aatagtatat taaacgttat atagaagcat
    17281 ctacttataa tttctcctgt atttatacaa ataaatatga gaagaacctg ttccaaaaat
    17341 acagatggtg ttattgtttc ggagaagtta ttatttttta tcctattctt atttctaaaa
    17401 aatttacttc caaatctctt tagatttcta ttatatctag gaatcgacaa gtctatattt
    17461 gatgatggtt ttaatttata tttatttatt agaaatttag ctacaggaca tcccaatata
    17521 ccacccataa taagtcctat tgttgcagca gataatccaa ccccaactgc tccttctata
    17581 ccgagatttt ctattgtaag tccaaatgca gcagaataac catgaccacc ttccatagat
    17641 acatttccac acataagccc taaaagaggt tcaagtttta taatctttga tattgtaata
    17701 gctaatatat tttgacaaaa tgccaatact ccacacaaaa tccaatatct aaataataca
    17761 ctaccccctt tctttataag atttatgctt atttcgagtc ctatagttgt aaaaaagaaa
    17821 gttataaaat ttggcattaa atttccactt atagatatat ctgctatatt aaaatattta
    17881 aaaaataaat ttagaaaaca aaataataga cctcctatta ctggtgcagg tatacagaaa
    17941 ttatttaaaa agttaacttt attattcaat aaattaccaa ttaaaaagaa gaatatagat
    18001 agtgtcaagg tttgcactat atcaaaactt aaggtaatca aaataagtcc tcctttgtaa
    18061 ttcaaagttt taattatata acttaaattc ttatgtattg aaattttatt atcaaatgta
    18121 tattaataaa tgtatattaa aaagaatcag tagatataat tagatagtca taaattaaat
    18181 taaaatattt taatgagata tgactttttt agaattaaaa accgtagtat attgatataa
    18241 tagaaataag acttaaaaat ctgttgatag tattatttat aagtacagta ggaggataaa
    18301 atgtttgaaa atttacctaa gatagattta cattgccact tagatggaag tgttagagta
    18361 gaaaccatgc ttgatatagc tattaaagag aaaatagatt taccttcaaa taatatggat
    18421 gaaataaaaa aattagcaaa ggtttctttt aattgtactt cactagatga atatttagaa
    18481 aaatttgatt tacccttaaa agtaatgcaa tctaaggaaa atttaaaaag aattactttt
    18541 gaacttttgg aagatgcaag tagagaaaat gtaaaatata ttgaaattag atttgcacca
    18601 ttacttcaca cccaaaaagg tatgagtgtt aaaaatataa ttgagggtat aattgaagga
    18661 attagagaag ctgaaagtat ttatgatata aaaggcaatt taatattagg ttgtatgaga
    18721 acaatgacct caaaagaggc attattagta attgaagaag ggaaatcatt tgtaaataaa
    18781 ggtgttgtag cagtagactt gtgtggtcca gagaaagagg gattttgtaa ggaatataaa
    18841 gatgttttta aattagcaag agaatatgga tataaagtta caatacatgc aggagaagct
    18901 gcaagtggag aaaatgtatt ggatgctata aatattttaa aggcggatag gattggtcat
    18961 ggggtaaaaa ttaaagacca taaaaaggcg tataatttag ttaaagataa aaaaatattg
    19021 cttgaattat gtccaactag taatgtacaa actaagacag tagattctta tgaggtacat
    19081 ccattttata ctttttataa agataattta catgtaagta taaatactga taatagaact
    19141 gtatcagata taaatttaag ttcagaacta aatgttatat ttgatacttt taaactagga
    19201 ttagaagact ataaaataat ttatagaaat gcagtagaag ctagttttgc agataaagaa
    19261 actaaagagt atttgaatag tttaatttaa tagataaaaa tatttaaact ttaaattaag
    19321 ctattaaatt gacaaaaata cattgtatta ggagaaaaaa tgtgaaagat tatgaagatg
    19381 ttgtttatat taaactagtc aaaaaagaac ttgaagaatg gaagaaaaat atattaaaga
    19441 aaccttctat atttgacaaa gcatcaaagg gtatacagaa taaatttaat ggagtattgc
    19501 cagataaata tcatgaaata attacttctt ctataaaagt aatgacaaaa accgtactgt
    19561 ttggatataa atatgctaca aagccaccac ttagaaatat gtcattagaa gaaagagaaa
    19621 aattagtttt agaaaaagct aaaacttaca agactacagc aatgattgaa ggggcaggaa
    19681 caggggcagg aggaatcctc ttaggtttat ctgattttcc tttgctttta ggtattaaag
    19741 tgaaattttt atatgatgta gcttcaatat atggatatga tgttaaagat tatagagaaa
    19801 ggatttatat attaaatata ttacagttgg ctttttctag tcaacagcat ataaacaaaa
    19861 cttttaaatt gatgaataac tgggatgaat atgtaaatag tctaccagaa gacatcaatg
    19921 attttgattg gagaacattt caacaagagt atagggatta tttagattta gctaagtttt
    19981 tacaactaat gcctggaata ggagcatttg taggatttta tgtgaatgga aaattaattg
    20041 ataaattatg tgaaactgct gtgtctgctt atagattgag gattcgagag cttaagttat
    20101 aagaaaaatt ataacataaa aaattagtta tacaatatat ctatatgtat ctaattttgc
    20161 attgataaaa acaattatgg ataaaaggta aagcatgata gaatctaatg tagaggtttg
    20221 tattttaatg gaaaaattta gtttttattg cttaagatac aaattgaatt acgaagagat
    20281 tgaattatga agagaagtaa ttgggaggaa tattttcatg acaaatttgc caaaacaatt
    20341 tgatagcttc aatgaagcta gacaaaaagg atttataaat gcaaaggaac ttaaggaaag
    20401 tgggaaaaag atggttggag ttttctgtac atttactcca gttgaaattc caatggcagc
    20461 tggagcaact gtagtaggtg tatgcggtgt tagtgaagag ccaatacctg atgcagaaag
    20521 ggtgcttcca agaaatcttt gtcctttaat taaatcaagc tatggacatg caataacaga
    20581 tacctgtcct tatttctatt tttctgattt gttgatagga gaaaccactt gtgatggtaa
    20641 gaaaaaaatg tatgaagaac ttgcaaaagt taagccaaca tatgtaatgc atttgccaaa
    20701 tacttcaaaa ggagaatttg cctataaact ttggaaagat gaaatgataa gattaaaaga
    20761 agaggttgag aaatctttag gtgtaactat aactgaagaa gatataagaa ctgctataaa
    20821 agataaaaat gaagaaagag aacttttaaa agagttttat gcacttggta aattacaacc
    20881 atctgcactt acaggccttg agttacataa tgttttatat caagcaggtt ttaaatttga
    20941 ccgtgcagaa cttaaacatt ctttaagaaa agttatagat gatatgaaag aaagatatga
    21001 aaaaggtgaa tgtcctgttc aaaaagataa gccaagaata ttgataacag gttctcctat
    21061 tggtggaata agcgaaaaaa tagttaaaac tttagaagat gcaggggcat cagtcgttgc
    21121 atatgaactt tgtggagcta ttagatcaaa cgatttattg gttgatgaag aaatagaaga
    21181 tgtatatgat gctttaacac aaaaatatat aaatataggt tgttcttgta tgatgaataa
    21241 tgacaatcgt attgaattat tagatagaat aatagatgaa tataatgtag atgctgtaat
    21301 agatgtagtt ttacaagcat gtcatacatt taatatagaa agttatagaa taagagaatt
    21361 tgttacaaaa gaaaaaaata agccatttat gtctcttgaa actgattatt caaaatcaga
    21421 tactgaacaa ttaagaacta gatttgaagc gtttgtagag atgttgtagg aataaataaa
    21481 agtaggagga actatgttta gtataggagt tgactcaggg tcagtggcaa caaagggtgt
    21541 gctatttgat ggtgaaaaaa ttattaagaa aataattata ccaactggat ggagccctaa
    21601 aagtacatct aaacaggtct atgagttgct aagtagtgaa attgacaaaa aagatataaa
    21661 aaaggtggta ggtacaggtt atggaagggg agtaatggat tttgctgata agaaagtaac
    21721 agaaataact tgtcatacta gaggtattta ctttttaaac aataacataa ggactatttt
    21781 agatgtaggt ggtcaagata gtaaagttat aaatttagat agagatggaa atgtatttaa
    21841 ctttataatg aatgataagt gtgctgcagg aactggtcga tttttagaga ttacttctaa
    21901 ccttttagga agcgatattg aaagtataga tacattagct aaaggatatg aaccagttaa
    21961 tatatctagt atgtgtacag tttttgctga gtctgaaatt gtaagtcttc tagctcaaaa
    22021 catttctact ggagaggtag cagcagggat acttaaatct attgcaaata aatccacctc
    22081 aatgttagca agaggtgagg taatagatga agttgcattt actggagggc ttgcaaaaag
    22141 taaagaacta gtaaaaatga tagaagaaat actgggtaaa aaaattttta ttgcagaaga
    22201 tactcaaata ataggagctt taggagctgc tgtaatagga tttagataaa aacatataaa
    22261 aagaaaatga gaagctgaat ttattataaa taaattcagt tttttatttt attttattta
    22321 tttataaagg aaaactttgg tataattgat ttaaatgatt gtatatttgt aaatacttga
    22381 tatttagtca tatataacat tataatttta aaaattagct caaaataagg gggagaaagc
    22441 gtgaaaaaat ttacttcaaa aaaagtaaca aggtttgttg cgctgttttt aatatctatt
    22501 ttagtcatgt caacaattcc tgtatcagct gacaatagca atacattgaa tcagataaaa
    22561 aaagcagaat acagtgagac gtataaacaa tatctaaatg atgctaaaaa tggacgtaca
    22621 gaaaaatata atgggattat accaaatcca tatcagttgg aaggtactca aatccaaagt
    22681 aaaggaagaa cagctccaac atcttatgac cctagaaaat taggtcttat gacatcaata
    22741 aaaaatcaag aggatttagg aatctgttgg gattttgctg caatggcaac cttagaaagt
    22801 ttcttaaagt taaataatta tggagactat gatttatcag aagaacactt aagatggtgg
    22861 gcttcagatg gtgaatatgg atggtctgta aatgatatga atggtgcttt aaattatgaa
    22921 gctatgggat atttaacatc ttggtcaggt cctaaattag aaaaagatat cccatacaat
    22981 ggtagagtat ctaaagcaca aggagcaaaa aaaccaacta atatgaatac agcacctact
    23041 gtttttaatg tgacagatgc tgtgtgtgta agcaatgaca taaattctac aaaaaatgct
    23101 atattacagt atggagctgt aacatctggt tattatgaag atattaaata tcaaagtgat
    23161 gaccaaaatt catattattg tccaacaaaa agttttaata caaatcatgc tatttcaatt
    23221 gtaggttggg atgataacta ttctaaagat aattttaatt caaatattag accatcaaaa
    23281 aatggtgctt ggttaataaa aaatagctgg ggagattata attctgaggg tggatatttc
    23341 tggatatctt atgaagacaa gacacttatg tctgatatag ataatttttc aatcaaaggt
    23401 ggtaaaaaac caaatgatga tgagaagatg tatcaacatg actatgcaag tattgtacct
    23461 ttaatttcaa aaaagataac agctgcaaat gtatttgatt tcaatagagg cgatgaaact
    23521 ttaaaatctg taatgttctt aactgaaagt ataggagcta agtatgaagt atattatgct
    23581 ccagtagtaa atggtatacc tcaagaaaac aatatgaaaa aattaaaaga aggtactgcc
    23641 caatattcag gatacataac agttccaatt gattcttttg atataccaga aggaaagggt
    23701 gcaattgtag tcagtataga ggggaaaaat ggagagtcaa ctataggttc tgagtcaaat
    23761 gtaccaggat atgatacatt taaagcaaaa gctaatttag gtgaaagtta tatcatagat
    23821 aatactggaa aattctttga tataaataga gatagtaact tctatccgtg taattttact
    23881 ataaaagctg ttacagaaaa gtcttctggt gagagtatcc caaatgagtc tttaattggt
    23941 agtgatagat atgaaactgc tatcaaagtt agtcaaaatg gtttcaattc ttcagaaaat
    24001 gtagttttag taaatggcag ttcaatagta gatgcattgg cagcaactcc ttttacatct
    24061 gctataaatt caccaatatt attgacacaa aaagaagctt taaattcaaa aactaaagct
    24121 gagatacaga gattaggtgc taagaaagta tacctaatag gtggagaaaa ttctataagt
    24181 aaagaaattg aacaacaatt aaaaagctta aatatatcga tagagagaat atcaggaagt
    24241 gatagataca agacaagttt attattagct caaaagttaa atggtataaa aaatgtatct
    24301 caaatagcag ttgtaaatgg agtgaaagga ttagctgatg caattagtgt aggcgctgca
    24361 gcagcagaaa ataacatacc aatcatactt gcaaatgaaa agagcgaatt gcaaggagct
    24421 gatgaatttc taaattcatt aaatatagag aaatcttata ttattggagg aacagcatcc
    24481 ctatcaaaca atctagaaag taagttaaaa aatccaacta gattatctgg tagtagtaga
    24541 gacgaaacta attcaaagat aatagataat ttttataaaa aagatacttt aaaaaatgca
    24601 tttgtagtta aaaatggaat caagaatcaa aatgatttaa tagatggatt ggcagttggt
    24661 cctttaggag caaaaactgg gtcaccagta attttagttg gtgataaatt agctgatagc
    24721 caaaaagaag ttcttaaaaa taagacttta gaaaaagtaa ctcaagttgg tggaggagca
    24781 aataaaaatg catttaaaga gttagtaaaa ttaaaaagtg ctaaataagg tacttaagta
    24841 ttaacatata ctagtgtcta ttagtaattt atcttaataa aagctgaaaa taattacttt
    24901 aaattattga taaataagat aatcaatgat tgtaaaattt tattttcagc tttaaattta
    24961 tgtagtataa gtttaaaaac ataaaaaagg gttactttat atagaaatat agaaaatctt
    25021 acattttata tataaataac ccatatttaa ttaacttttt atagtgttct aatagatatt
    25081 attgaactta atggtaaata taatgtgtaa gtttcattta aagttggatt agattcatct
    25141 atatatcttg agcaaagtgt aattgataag ctatctgctt ctataatttc accatataga
    25201 ggacaactgc taaagtaaga atgtacttca acatatttat ttaagttttc ttgaacataa
    25261 tcgtaaaaac ggttttttgt agtagtagcc ataaaatcaa ctcctttatt ttttattaaa
    25321 gttgaaactt ttaaaaagat aaatatgatt acttctatta gaaactaagt taaaaaataa
    25381 gcaaatagat atgaaaatta gaataatata ttatttatat cttaattata acactagata
    25441 ataaaaaatg ctatataaaa ttcagaattt tcgaaagttt ttaagcttat ttttaaatat
    25501 actaataata ctattgacat tagatagaaa aagtattata ttgactatat aaattatttt
    25561 agtcaaactg gaggaaaaag atgcctaaat catattctga taaagaaaga gagtatataa
    25621 taaaaagact taaagaagaa gcaagattgt gtatggagca atatggtatt agaaaaacta
    25681 ctgttgatga gcttgtaaaa cgggtaaaaa taccaaaagg aactttttat ctattttttc
    25741 aatcaaaaga attgctcttt tttgaggtat taagagatat acatgactct atacaaaaag
    25801 aaatcttata tgagataaat agagtagatg aaagtattac atgtgaacaa ttgacagata
    25861 tatttatgaa attctatagg atggttgata gtacttcaat tttaaatctc atgataaatg
    25921 gagaatttga gatattggtg agaaagttac cagattctat aattgaagaa cactttagac
    25981 atgatgactt tgaaattgga gagattatat cttgcatacc aaatgcaaaa aataaagaca
    26041 tagaaagctt tagtggagca tttagagcag tttttcttac catgctatat aagcgcgagg
    26101 ttggaagtaa ttgttttgaa gatgctttaa gattaatgat aaacggatta gttatacaac
    26161 ttatggaata gaatttaaat tttgtttgct aataactttt attaaaaatt attaacaaac
    26221 aaaaaaatta tattttattg accatatagt caaaatagtc aaaaatttga aagggtgata
    26281 ttgaatgatt aaagttgatg atttatcatt tagttataca gatagagatt ttttacaaaa
    26341 tattaacttt ggagtaggaa aaggggaaat actaggattt ttaggaccat caggtgcagg
    26401 aaaatctaca ttacaaaaga ttctaattgg aatgataact aattatggag gaagtgtcat
    26461 tgtaaatgga gtagagagta aaagacactc aaataaattt tatgaaaata taggagttga
    26521 ttttgaattt cctagtttat atgaaaagtt gactgcaata gaaaatttaa aatattttgg
    26581 gtctctatat tctaaaaaac tactatctat tgatgagtta ttaaaatcag taggactaga
    26641 aaatgaagca aataaaaggg tatctgagta ttcaaaaggt atgaaatctc gattaaattt
    26701 tataaaagct ttattacata atccagatat tttattttta gatgaaccaa caagtggtct
    26761 tgacccatca aatagcaagg ttatgaaaga tataatttta tcagaaaaat tgaaaggtaa
    26821 aactattatt ttaacaactc ataacatgtt agatgcaaca gagctttgtg acagagtagc
    26881 gttcattgta aatggtaaaa tatctgcttt agatacacca cataatctta ttatgtcaaa
    26941 aggagctatt aaagttagat atacttactt tgataatgga gaaaaaactg ctgaatgttt
    27001 tctgaacaat actgctaatg ataaaaattt gaatatgctt attgagaaaa ataaactttt
    27061 atcaatacat agtagtgaac caacattaaa tgatattttt attgagataa cagggaggaa
    27121 tttacaatga ggctaaaaaa tcttatttta ggagatataa agtttcaatt taagtatggt
    27181 ttttattttt tatatctttt tttaagtatt atatatattt gtattatcaa tgtatttcca
    27241 acttttatga gagaaaaaat agttataatt atgatttatt ctgacccagc agcaatggga
    27301 ttgtttttta tgggagctat tgtacttctt gagaaaagtc aaagggtttt aaattcctta
    27361 gctgtatctc cagtaaaagt atctgagtat attttatcaa aggtaatttc attaggagta
    27421 atatctagta ttgtagctat gtttattgct attacattaa atttagataa tattataata
    27481 tcaactatag gtaccttttt ttcttctatt atattttctt tgcttggatt gatacttgca
    27541 agtaaagcat ctagtttgaa tcagtttatt gttttaagta ttcctattga gattatatgc
    27601 tttattccac caatactcaa tgtacttctt gacacaaaat catatgcaaa tttgtaccct
    27661 tttaatatat gtatttctct tattagtgga gataaaaatt ttataatgat taatatttta
    27721 attttaatat caattataat aataatttat tttataactt attattttat ttgtagcagt
    27781 tggaaaaagg taggtggagt aaaactatga taaagattat aaatgcgttt aaacaagagt
    27841 ttgaacaaat taagagagat gctatgcttt ttatagtatg tgtttctcca atattatgtg
    27901 gagtatttat aaaatttgga ataccattaa tacagaatat atcacttaac aagttttatt
    27961 atcaattaaa tttagagccg tatttcttga tgtttgattt acttttagct tttattacac
    28021 cttttatgtt cttttttgct tctacaatgg tcatattggg agaaattgat gacagcattt
    28081 caagatattt aatagtaact ccgcttggta aaactggtta tcttatttca cgatttggaa
    28141 taccaggtat cttagcattt attattacta tgattctact tatctttttt tctctaacta
    28201 aaatttcttt cttgttaaac ttatcaattt ctttattagt tttattacaa ggaattatta
    28261 tatcaatatt agtgatttct ttatcatcaa ataaactaga aggaatggta attacgaaat
    28321 tctcaggtgt ttttatgctg ggtattttag caccattttt tattttaaat aaagcacaat
    28381 atattctgtt cttcttacca actttttgga tatcgaaggc atttaaggaa gataattata
    28441 tctatatgtt tatttcaatt gttatatcat taatatggat tttattatta tttaaaaagt
    28501 ttagtaaaaa aatagttaaa taagaaaatt taatatataa atgtaaggtt gacttgacag
    28561 taatgttgaa aaatgttaca tttaagatgt aaagttaacc ttacatgaat ggagcaaata
    28621 tgaaaaataa aataaagata ttaagagaaa aattaggatt gacacaagaa caactaggga
    28681 gattagttgg aacatctaga caggctataa atgctataga aactggtaaa aatgaacctt
    28741 caatatggtt ggcatatgat atttcaagaa tttttaatga accaattgaa agtgtatttt
    28801 tatttgaaga aagtgaaaga aaatcaagag cacagataag taggggagaa tattatggct
    28861 ataagaaaga taagaacatt tgatgatgaa attttaagaa aaaagagtaa gtatgtagaa
    28921 aacgtagata ataagataag agaaatatta aatgacatgg cagagaccat gtacaatact
    28981 ccaaatggag gaggattagc tgcatgccaa gtaggagtat taaagcgatt agttgttata
    29041 gatttaggag aaggacttat taagcttgtt aatcctgaaa ttattaaaca agaaggggaa
    29101 caaattgttg ttgaaggatg tttaagtttt cctgaagtat ggggtaaatt aaaaagacca
    29161 aaaaaagtta cagtacaagc tctaaacgaa tacggtgaga aaatagaaat taaaggttca
    29221 ggttttatgg caaaatgtct ttgtcatgag atagaccatt taaatggtat agtttttaca
    29281 gataaaatta ttgaacatgt aaaattgtaa gatagattgg ttattgaatt tataaaatat
    29341 tttatagtaa ggagttaaat tatgagatta tggcataagg atttaattga tgtattacct
    29401 aaaaatcaat tagtaagtca atggagagag ctacttgcta taaaaggttc tatagataaa
    29461 aaaggtactc caaaccatct attagtgaat aaagtattga attatagtat agatgaattt
    29521 aaattttata caaaaattgt acatgatgaa atgttaaaaa gaaattataa acctaatgaa
    29581 cttaaatata caagtatatt aaaatggaaa aatagaaatt ttgcaaatga tatatctaat
    29641 gaacatagtt taaatttaga aaatttatat gatgattggc ataataaaat gtatttaaag
    29701 caatgcttat ataatttaga agaaaaagca acatgtggag gaataccaat aaatgaatgg
    29761 aatatattac tttgtaaata tagtaaagat tatgaattgt ggtctggaaa tatcatgttt
    29821 taattactat agattaacat tatagtatta ttgtatataa agaggtgatt atttgtataa
    29881 taaaataaaa tatattccaa taaattgtga aatagcttgt aataaattaa aaaggagtat
    29941 gccatataaa tgggatttaa atatttatcg tggatgtgag catggatgta aatattgtta
    30001 tgctatttac tctcataagt acatcaactc caataattat tttgaagaga tttatgtaaa
    30061 aacaaatata gtagaaaaac ttgagagaca acttaaaagc agtaaatgga agaaagaagt
    30121 aatcaatata ggaggagtta cagatagtta tcaaccaata gaagctgact ataaaattat
    30181 gccagaaata ttaaacctgc tgataaaata caagacacca gctattattt ctacaaagtc
    30241 agatttaatt ttaagagatt acgatttaat tgataagcta tctaggatta catatatcaa
    30301 tgtagcatct acaattacca cagtaaatga agatacacaa aggcttattg agccaaatgg
    30361 tgtggattca atgagacgat ttaaaatgtt aaaagaattt agaaaaacta acgcatcagt
    30421 tggtctacat attatgccaa ttataccata tattacagat gattttgata atataaattc
    30481 gctatttaga catgcaaaag aatgtaatgt acattatgtt ttacctggga ctttatactt
    30541 aaggggtata actagaggtg ttttttttga ctttgttaaa aaagagtttc ctgaattatt
    30601 tgataaatta tcaatactat atagtgcagg ttcacttaat agggagtata aaaatcaatt
    30661 gtataaaatg gttaatgaac ttagatataa gtattctcta tcaagcagtt actctaaaat
    30721 aatgaaggaa aagttaaaaa actcaggaga tgtacagata tctttttttg attagtttta
    30781 tataaaaaaa atttttttac tatgat
//
LOCUS       DAMJXI010000042        29425 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.044, whole genome shotgun sequence.
ACCESSION   DAMJXI010000042 DAMJXI010000000
VERSION     DAMJXI010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29425
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.044"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            469..3111
                     /gene="adhE"
                     /locus_tag="PC465_002462"
                     /gene_synonym="adhC"
     CDS             469..3111
                     /gene="adhE"
                     /locus_tag="PC465_002462"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDF2649748.1"
                     /translation="MEKKEKVVEKSNVEVCSPEIVNSVETLRMRLEEIRLAQKEFATF
                     TQEQVDKIFLAASTAANQQRIPLAKMAVEETGMGIVEDKVIKNHFASEYIYNAYKDTK
                     TCGVIEKDEAFGFTRIAEPVGVLSAVIPTTNPTSTAIFKSLIALKTRNGIIFSPHPRA
                     KNCTIEAARVVHDAAVKAGAPKGLIGWVDVPSIELTNVVMAEADLILATGGPGMVKSA
                     YSSGKPAVGVGPGNVPAIIDESADIKMAVSSILVSKSFDNGMICASEQAVIVPEKIYE
                     EVKKEFKYRGAHFLNKEETEKVGKVVIIDGSLNARIVGQPAHVIAKMADVEVPKTARI
                     IIGEVESVELNEPFAHEKLSPVLAMYKSKSFEDAVAKAEKLVADGGYGHTSSLYADSI
                     NHPERVEKFVNAMKTCRVLVNTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVG
                     VKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVAAREFKDVMDKKKAFIVTDSFLY
                     NNGYTKKLTDLLDEMGIKHTTFFDVAPDPTLACAREGAKAMADFQPDLIIAVGGGSAM
                     DAGKIMWVMYEHPEVDFQDLAMRFMDIRKRVYVFPKMGEKAYFAAIPTSAGTGSEVTP
                     FAVITDQDSGVKYPLADYELMPNMAIIDADMMMEMPPRLTAASGVDALTHALEAYVSM
                     LRTEPADGLALQAGKIIFEYLPRAYKNGKNDKEAREKMAMASTMAGMSFANAFLGICH
                     SLAHKLGAFHHVQHGVANALLINEVIKFNCAEAPNKMGAFSQYRYPDCIQRYAEFASF
                     AGIKGSTDQEKVDNLIKAIDELKAKVGLPKTIKEAGVEESKFLERLDAMVEQAFDDQC
                     TGANPRYPLMSELKEIYLKVYYGK"
     gene            complement(3471..3812)
                     /locus_tag="PC465_002463"
     CDS             complement(3471..3812)
                     /locus_tag="PC465_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649749.1"
                     /translation="MLLILGNLNLNLDFDYRIIREENDDVDIFIDINYRSLDIDTDGS
                     NLFNSRIQFPFVRALILRLNKNNQCMTIHLLRDIDLFSAFANFEVDYTDSIVNIKNQN
                     EKVILNKSIKK"
     gene            complement(3839..4510)
                     /locus_tag="PC465_002464"
     CDS             complement(3839..4510)
                     /locus_tag="PC465_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2649750.1"
                     /translation="MPILETINLGKIYGKKETSVHALKNANLKINKGEFVAIIGPSGS
                     GKSTFLHLVGGLERPSNGTIKVAGKDICCLSDKELARYRRQKVGFVFQQYNLIPVLNV
                     KENIELPLKLDNKKIDKEYIEDLINLLGLKERKNHLPNQLSGGQQQRVAIARALSAKP
                     SIILADEPTGNLDSKTTEEVMDLLKSSIKKYNQTLIIITHNENIARKADRIISIIDGE
                     LKLTL"
     gene            complement(4522..7098)
                     /locus_tag="PC465_002465"
     CDS             complement(4522..7098)
                     /locus_tag="PC465_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2649751.1"
                     /translation="MKDNLKIVLRYIKSYKARSLAIVVSIILATSLVVGIGTLSRSAQ
                     QADVDRLKRELGTDHVYFKNIKKNQLKSIKSSKDIKNLGITSYYASTDVNEKLPINIL
                     YANKNYLTSHSKLIKGRFPKASNEVVVEKWILNSMGLKPEINQNLTFKLYQKENPETF
                     KVVGILEDRFIEKKRGQCEIFSNLNESELNNFTTYIEFNEGSDINTNIDNIIKNAMLD
                     EKSIGRNSMLIESTMKNGTLDNSSKYIAIAMSLFAGIVIYSIYVISIYQRVQEYGILR
                     AIGSTNFRIFKLMLYELFILALIAMPIGICIGMGGAQIFNRSVGNIQFEGNINVTPFV
                     IPDKIILLSIACTILIMLIISFFTYLKIRRISPIDAIRKTFGSDKNVTKVNYLISKLT
                     LNMSVTKSISAKNIFRNKKGFMIIVLSMSIGGIIVIKDNYKYSFLDVQNKSVQEQTYM
                     NADFILSNVYLNETGNNTSFKDIKGFSDSQIDKIKNIDGIDKVKTASILNTRIEVNKI
                     NRLDYYEAINSTPYYKLNPLFIKNKTTGKYTLKQKLKGYNDEMIKSLEKYLVSGNINL
                     KKMKKENLAIVYVPEISKTQKYTKTFTPGEGTPAVDIKVGDTIKVKYPNGGMDTGLYE
                     SLKDNYEYLEYEFKVGAIISYPFADNGMYSGDDSVDVITSSEYLKKLTGVDKYNLVYA
                     DLNENANKKKINNLLGKIGSEVPGTTTVDMMVEKENSDKMTSRTMIYSYGIVAIMFII
                     SVLNIINNISYNLTSRTSEFGMLRAIGISERGFKNMILYEGILYGVLSSIITIVSGLI
                     IQFKMYYMQGFVSYGLGFSIDYKIYILVVVANIIVGILATYIPSRKINKISIVEAINI
                     TE"
     gene            7306..8241
                     /locus_tag="PC465_002466"
     CDS             7306..8241
                     /locus_tag="PC465_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2649752.1"
                     /translation="MDNNFVFPIVILTLFIFSNLIMNKYKFYKELDILKRGILTFFIS
                     CFALILFMEGTKYIQLRLGYSFLLEGVLNIILFLVLIILSFYTGFKVIRLINNNNEQE
                     YKLQKLDSKINHKDNIIIKLRSQKHDYLKHLQVVYSLLNTGLDEDAKEYIMNISNSFK
                     SKNSRYGKVSYLDAIASLKYEECLEKDISFDVYIQDFMDNLEIEPNDMSSVLLNIIDN
                     AIESLSTIKKEKKYIRLHAYEDEFQYIIAIKNNGPKIHNVESIFWNGFSTKEGQDRGY
                     GLHLVKNILDKYDYSILVNSDDFLTEFVILIPKYY"
     gene            8260..8997
                     /locus_tag="PC465_002467"
     CDS             8260..8997
                     /locus_tag="PC465_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2649753.1"
                     /translation="MIKVLICDDDKIVRDDIANIAKESGYVDYVKKVKDGIEAIEFIK
                     NEKIDLLIIDIDMPYKNGIDSAEEILSIDKDIHIVFVTGFADYSLESFKVHPIDFVVK
                     PFKKEKILDSINIAIDHINSHKIANNNFIEDTLFVYKIRKQIHMINFDDIVMFEKNSR
                     AINLHTKDEDIIKFYENFDDLKKRLPPNFFMTHRQYIVNLRFIHKVIPINKSSLEIRF
                     INFQENAILNKSLEKDFLYRFYRVKRF"
     gene            complement(9182..14239)
                     /locus_tag="PC465_002468"
     CDS             complement(9182..14239)
                     /locus_tag="PC465_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HDF2649754.1"
                     /translation="MLERTRVEKNPKIIENFKNNFTKSSSKQYYDLAKSLWDCIENSS
                     YYYREPEDKFLNMIKKYYNCHYYEIKNMDELLSGPLKNALELIFTSEQVEELCQLIKR
                     KMDYTYSGGYYRKGYRSNKLVDYFRGIIRFISNYVDLIYYDFSVIDYLTLPNKVLYYD
                     SIMSDKIALEIDKGNQKVISALEEVIFGENQTALLTRQMIIGIMKSHSDKCYEMLSKL
                     LLAAKQQEGLRQQIVESLDEGTISASIYMLKTILDNNLERFSSVIRALDTWTGLGFSD
                     QKPGIIRKCLELSYKSLTDEKFRIESINSNDNLEIYFALWATATYNIYDSYSLIENLL
                     SCQEKYKKLVALYFLSHTESTYFKHSIASKNIKGDDLEILAWVITNFYVEGSVGYYYS
                     WQNRETNFDLSNTPIDKDFDARKEQFESLKHTLEILNSKTKSFSGSVFPWTWIEISSH
                     EILKCMMTLTAYDMNAQFIDVLMENCHLMSSDLRASLIVNFVNEPKTDRQREFLLECL
                     SDKSVSNRETVLSLLRKLELTDVELDKITNLLSLKTSSIRQTVIKILLEQDDSNLENI
                     ASSLIKSSNSQKCLGGLEIVNLLKDNTARQELYNKLVLLIEDIDKSKKNTSQVQILID
                     NLLGKAKNDYCKENGFGIYNHENKVQIPEQFDFKDDSNSSSKLNKIISNISLSTREDS
                     VSVATKKEAKKILDTDINKIIKVYEKFDELITENADYEYEVERWSGNVDKVLLGYSTY
                     NLTPIKYKVSNDTLDNYPLAELWRETSKKLDLDYKLILDILFYSISTCGYNETEKSWF
                     SSIYSNVLDSKKQNKIYTKLEKLKFNGLTRKLLRVLLNEFDHKEIFNYCLEIYYKLRN
                     LLTIEQCKKQRVEFTKNYYRQNEYCPALNAPILNYWLDKAHSFIYDDISFTKFFYTTF
                     SNYQLLEYKFPFYTSINVFARAHELGLMTEEQVNREMISGYNASNIIRTLTNPRWAGD
                     TLEKYPWLKDNLKTVTNRIIEIESRRGDMPTEVSHLANNIQYFEGINYFVNILVALGK
                     ETFQRGYSYGSNYSKKDVLSSLLKNCYPTKEDDSKKLKSLLKNTDITELRLIESAMYA
                     PQWVNIIEKYLNWKGLKSTIWYFHAHINEGFSAQKESEVALFSPISPRSFIDGAFDVD
                     WFLDSYKTIGEERFNILYKSAKYITSGGNSHRRAQLYADATLGKLDKDMLMKEIETNR
                     NQDKLRSFSLLPMKKGDLKEATFRYEFIQKFAKESKQFGAQRRESESKACTIALENLA
                     RSAGFGDVNRMMWALETEKLNEVAHLFKPKDIDGTSIWIDVDENGKASTKVQKGNKSL
                     KSIPKAIAKHPYVLELKSVQKDLKSQYSRAKQSLEQAMKNEIVFTVKEIANIYKNPVI
                     CPLIKNLVWVCDDNIGYVYNDKSKFFICNIEGETYKLTAKNKLKLAHPVHLFESGKWS
                     EFQHDLFSKQIVQPFKQVFREYYRINSDELSEKTISRRYAGHQIQPKKTVALLRNQLW
                     TVDYEEGLQKVFYKENIVAKMFALADWFSPADIEPPTIETVEFFDRKTYKSLELASIP
                     PILFSEVMRDIDLVVSVAHAGGVDPETSHSTVEMRIAIAKELLLLLKINNVNFEGSHA
                     LIAGNLGEYSVHMGSGIVHKKGMGALNILPIHSQSRGKIFLPFADEDPKTAEIMSKIL
                     LLAEDSKIKDPSILSNL"
     gene            complement(14264..14683)
                     /locus_tag="PC465_002469"
     CDS             complement(14264..14683)
                     /locus_tag="PC465_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649755.1"
                     /translation="MQIYFRVKAVGKRKPMLELTPFDVSDNINCLKEAISEIVSKNVL
                     EYNEKIPEKSIINFLTNEEIESQADIGKVGFGSIYNENKQSVEKAIEVALQAFEDGIY
                     KVLINEDVIEKLDSSINLKSGDIFTFIRLTLLAGRMF"
     gene            complement(14916..15167)
                     /locus_tag="PC465_002470"
     CDS             complement(14916..15167)
                     /locus_tag="PC465_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649756.1"
                     /translation="MNRYTKIINMMGSYYTKDFEKEKKNVIKVREVKEDTVRKFFLQG
                     DCEVLVVFEDTGKEILIDDFSPEEDIKKYLGAKFINKKR"
     gene            15256..15987
                     /locus_tag="PC465_002471"
     CDS             15256..15987
                     /locus_tag="PC465_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HDF2649757.1"
                     /translation="MTSIKNKDILNCIDYSIKNKLFDKLNDVYKSLPVGNCSGCGNCC
                     MESVGINLIEFLNIFCYLEDRVDLKKSCISKILDYYFEEYTRKNPCPFKDTNNRCLIY
                     EVRPLNCRMFGHWKKEDYNKNLDNVIEKNNNYRELMKKQYGFEINDEVVNYRIDYCDR
                     FIPNKDYLSKSKRLSFFDELMILDSNIYSSGNIDIDFRDRGIVEYFIESLLYRNLAYN
                     VKIRISKEYKIRKRTIDRIKRIVLV"
     gene            16046..16957
                     /locus_tag="PC465_002472"
     CDS             16046..16957
                     /locus_tag="PC465_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2649758.1"
                     /translation="MNLTKVKGNTFFIKGGTNTGIYVFEDNTALMIDPGLCGSRPRRV
                     NKVLDENNIQVRYIINTHGHDDHYGACNQFKEYYKDVCIMSSEYDKLYIENPELFSKY
                     IVGGKSNVFMDNILKNKMLDDIKIDKSIEAGKIELNNEIFDIIEFQGHTPGSIAVLTK
                     DNVIFVGDLLIGDEILSKYDFLFLYDIQEQINSLEKLKNIDFEYLVLGHGKQVISKED
                     SYKLIEKHLNALKKYLYQIRELLVEPKSLEILLKNIINNNNLSNNYKEYHFFKSSLVS
                     VISYLVDLEEIGYILENGELLYYTKTK"
     gene            17008..17820
                     /locus_tag="PC465_002473"
     CDS             17008..17820
                     /locus_tag="PC465_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HDF2649759.1"
                     /translation="MEYEKWNEILAPYEHAVEELKIKFKNIRKEYLAKGEYSPIEFVT
                     GRTKKISSIISKLKRINAKDIETEIDDIAGIRIMCQFVEDIYAIVDLIKVRNDMTIIG
                     EKDYITNYKDSGYRSYHVIIKYPINSIAGSKEIICEIQIRTLAMNFWATIEHSLKYKY
                     DHYIPETLAERLRRASDAAFLLDQEMSEIREDIMKAQAMYQMKSIAIRDTLNRIQELY
                     DLGDTHKAMQYQRKLDRTETDKNITEILELKQEIDILLEQYKDTKVDDKVVQ"
     gene            17929..18621
                     /locus_tag="PC465_002474"
     CDS             17929..18621
                     /locus_tag="PC465_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2649760.1"
                     /translation="MSLYAIGDLHFSTSVNKPMNIFGSNWDGHEKKIIDNWKEVVEEE
                     DMVLVLGDTSWGINLSEAKKDLDIISKLPGQKILIKGNHDYWWTTVTSLNKLYEDMRF
                     IQTNFYEYKDYAICGGRGWICPNDVKFDETDEKVYKREEHRLRLSLESARKSGHSKII
                     VITHYPPTNDKLEESLFTKLFEEYNVEKVIYGHLHGKESFKMGLKGIRNGVEYTLASC
                     DYTEFNLIKVHD"
     gene            18708..19649
                     /locus_tag="PC465_002475"
     CDS             18708..19649
                     /locus_tag="PC465_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649761.1"
                     /translation="MRWILVFIFLYLIPLVVIFRNYKNFKRSCIYSSIYVVLATTIMI
                     SNIYMSGLNKIKESMYYHNYISDETYDEKYVSNFKEKESTDLKQDNKKNEEISNNKNL
                     NNKQDRNIQNKESNEEGSNDIKEKNNSDSNVSVNNKSEKQEDNTKENNKYTSKEKNSE
                     DIKKIDMESIGIFKKEIYNIERAALVPMRECIPYTKDIAKNITKLSSIKKDVTNARNK
                     CKEVVKEYENMQIPELSKEKYTETLSNARDDVKKAYELREKSMESALKLINTKSPKYI
                     GKITEYLDLSDKQIESFKNRLNDLKEEINNSETNNIN"
     gene            19686..20843
                     /locus_tag="PC465_002476"
     CDS             19686..20843
                     /locus_tag="PC465_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDF2649762.1"
                     /translation="MNKQSIGKLNMFFMGITQRNLDNRDFFIELEVIFKSGRKEFKGI
                     AIEEDNKYKFNFKGKSDLYTFNELLKNISKEAENYDGLVFKYVERGTIVVIEGDNKKV
                     NVKYLDNKEEVPKIDEFTASQIKNRDYYVKVGQANALLKEIGVLTKDGKIKNDKIRKY
                     NQIDHFVELIDSILKEIKDKDCITILDCACGKSYLSFVLNFYIKEVLKKNCYFIGIDY
                     SDVVIEASKNMAKNLGYKNMSFIKEDLTNYTPNRDVDLVISLHACDTATDMAIGLGIR
                     AKSEAIVVVPCCHKELLGQYRYEAMEPILKHGVFKARFADLITDGLRTLLLEGNGYDT
                     SVVEYISPLDTPKNLMIRAIKTKTNNDKALKEYKELKSQFGVEPTLEKLIY"
     gene            20995..21555
                     /locus_tag="PC465_002477"
     CDS             20995..21555
                     /locus_tag="PC465_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDF2649763.1"
                     /translation="MNKLNICIDIDGTITSPYHFLPYLNDIFNKNITEAECITHNWEE
                     LYGSGIRDVYAEFNNKYIHSYDEAKIVEGATEVISTLSKGHNLSFVTARHECLTDVTK
                     NWLSRQGFSDIDVYLLGSDYKVEKARELSCDIFIEDNPLNSVQLADDGVKVILLDTNY
                     NKDVKHQNIVRVSNWIDIEKIIKQGI"
     gene            21583..22074
                     /locus_tag="PC465_002478"
     CDS             21583..22074
                     /locus_tag="PC465_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649764.1"
                     /translation="MIDLKIENRKGKIHVKSSEIKDILELRPDFEYVQDISNTINQEN
                     ILVFDCQLTGNSFDMDDLDIEEILEELGEEIDESYFSVLFEDVRAYLKDATDEIEADL
                     QDNYLFDNLRCYFDIYNINQEFTDFKFVFLVSFKDIKISSLANLAKIVSKRQLIGASK
                     FYS"
     gene            22303..22854
                     /locus_tag="PC465_002479"
     CDS             22303..22854
                     /locus_tag="PC465_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2649765.1"
                     /translation="MQSLNEIIAENLKKIRKEKHLSLDKIAQLSGVSKSMLSQIEKCE
                     VNPTISTLKKITNGLKISFTSLMERQESDIELIQKSDIDHFIEDNGKYISYPIFPFDS
                     KRRFEIFMIEIEEGGNLDSNAELPGTQEFITVFSGEVTIKINGEDYIVSSGNSIRFKA
                     DVSHIYRNSGKGIAKMSMVVYYI"
     gene            22940..23872
                     /locus_tag="PC465_002480"
     CDS             22940..23872
                     /locus_tag="PC465_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HDF2649766.1"
                     /translation="MNNKKAVFFFCSDLKKDPVASNVIKCCEEIMDLNQTDIFIDDNF
                     VLEFKDKNNNLFHFVKTKDVISHNYKYYLPILNRHFRDYDFAGVVNWHEGENAPEHIL
                     TAHTIGDVPTGEFGNSNPRYFKNLINAIEDIKNENLLDEFTTLTEATHWSGTTYGEES
                     KLITEYSVPMLDIEIGSSSDSFNNSIAIQVLAKSLIRVFDCDEPLKTLLCVGGVHFEK
                     SFSDIIKNKEYNISIGHVLPNQWIVSGMYDDESGFEKLEKCINSIEGGIDCIVFHDKL
                     KGTYKEQCRKLGEKLNVPVFKHKILKNPKDLPIW"
     gene            23926..24789
                     /locus_tag="PC465_002481"
     CDS             23926..24789
                     /locus_tag="PC465_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HDF2649767.1"
                     /translation="MILSYFALLIRVVLLAFERVVVRLLGDEEGDIYKNIASSFLFFF
                     IGGVCLLPFSIMDRVSDWSFLIPCYISSLVYSIGSVAYVTSLATGEVSLVTPINSLNS
                     LFLLLLSVIFLGEGLSLAKVAGIIIMIGGVFILKKVSSFLKNVSVIFNNLPCRLMFLY
                     IFLQSVGRVLDKAFFVQVSPILYSTILYFFVGLNLFIFLAFKKKQKIICEIFTNKKGL
                     SILSGAINGYSYLALLIALNNLELSIAEPFSQVSMIITLILAHFIFKENIKEKIPGSI
                     LILIGGWLLLL"
     gene            25036..26898
                     /locus_tag="PC465_002482"
     CDS             25036..26898
                     /locus_tag="PC465_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2649768.1"
                     /translation="MNYKKTAIDIIEQVGGSKNILALEHCSTRLRFKLIDRSKVNQDA
                     LKKVQGVMSIVNGAQFQVVIGNSVVDVYDEILKVCPLDTNDSTVKTEEKINLGTRFIE
                     FIINIFQPLIFAIAGAGILKSLLMLLAMFNILKSDSTIYTLLVAISDATFYFLPLMVA
                     VTTANVLKCNRLVAIAAVGYLLLPATTTALSEGVELFGFTIPNIAYNAQVFPAILCVS
                     FLATMEKIFNKYSPKPIRTFFVPMMSLAITVPITLTILGPLGYNVGTIFTTIILFLYN
                     KMGFLVVGLLAAFLPFMVATGMHKALIPYSINTIGKLGYEALYMTSSLAHNISESGAC
                     FAVALRTKDETLKQTALSAGISALMGITEPALYGITLQHKRAMLGVVFSSAISGTFLG
                     LFAVKGFVIVGPGLASMSMFIDPNNGNNLIFASIGFVIAILGSFIITLIIWKEDTNTV
                     ESSIGDVVEEELEEEKEVNILVTPVEGKVIDLSKVNDELFASKTLGDGVAIIPTNGNL
                     YAPCDSEVVMLFETKHAIGLRTKNGAEILIHIGINTVSMNGDGFKTFVKTGDNVKEGD
                     LLIQFDLDKISHANLDSTVMIVNNNGADYAYKVLNQSYGNVKKGSILFDVKGGI"
     gene            26901..28367
                     /locus_tag="PC465_002483"
     CDS             26901..28367
                     /locus_tag="PC465_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HDF2649769.1"
                     /translation="MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADV
                     KDYKSNNEITTKDIEEGLAHPEDEVNYPKRHGSDFYHHYKEDIALMAEMGFKTYRMSI
                     AWSRIFPNGDDKEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
                     RQVINMFVRYVETICEIYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVI
                     FQAMHHQFVASALATKICHEIIPNSKVGCMLTKLTYYPYTCRPEDVLATQQKMRSIYA
                     YSDTQVFGEYPVYLLSYFKNNNIQIVKEEHDDEIMKKYPVDFISFSYYMSSCEAADTT
                     GLDITPGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKD
                     ILTEDKKVHDQYRINYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRY
                     GYIYVDADDYGKGTYNRYKKDSFYWYKKVIENNSIDFK"
     gene            28391..29227
                     /locus_tag="PC465_002484"
     CDS             28391..29227
                     /locus_tag="PC465_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2649770.1"
                     /translation="MNYIIKKVLNSSVVLVHDTKDNEFILLGKGIGYGKKTGEYICGS
                     NDNQMFVPVENTKSKQFLELMDDIPVDILKITQEIIVEAEKLLNSSFNKNLYLILADH
                     FNFAIERMRKGIKITNRVFWEIKNYYPNEFKVGMVAIYMVEERLGIQLPEEEAANIAF
                     HFANAMASDGNSYDTIKYAKVIGEIINIFVFSLNRTLDKKSMHYMRFITHIKFFVERF
                     FSDSMLSSGDDLLFNQMKRSNPKEMLIALKVRDFLEKKYGKKLTNEEIAFLVVHIARV
                     KQ"
BASE COUNT        10913 a         3521 c         4689 g        10302 t
ORIGIN      
        1 gaataatttt agtttatata ttttttaaaa ctatacagtt gttataaaaa gaaaaattgc
       61 atacaagtca aaaataagtg ttattttata aaaatacgac aaaaatttta tttactactt
      121 atacaaataa catgcaaata acatataaaa tttaataagt aaaaaaaatg aaagatataa
      181 attatcattt tagtatttta tttagtcgaa gtaaattatt caaatgaaat atatctcatt
      241 tagataaaaa attttagtaa aagtaaaaaa aataatatat ttgttaaaaa ataaattgac
      301 aaaatattca gaaaaaaact tcttgaccta agagagtaaa ataaataaaa tctaaggtat
      361 agagatgaaa tctataaaat tattttaagt ataagttaaa aatatagatg atgcatttaa
      421 gatttataaa aattagagat gcataattat tttagggagg tttttagtat ggagaaaaaa
      481 gaaaaggtag tagaaaaatc aaatgttgaa gtatgtagtc ctgaaattgt caacagtgtt
      541 gaaacattaa gaatgagatt agaagaaatt agattggcac aaaaagaatt tgcaacattt
      601 acgcaagaac aggtagataa gattttctta gctgcttcaa ctgcagctaa tcaacaaaga
      661 atacctctag caaaaatggc agtggaagag actggtatgg gtattgttga agataaggtt
      721 ataaaaaacc attttgcctc agaatatatc tataatgctt ataaagatac taaaacttgt
      781 ggtgtcatag aaaaagatga agcatttggt tttacaagaa ttgctgagcc agtaggtgtt
      841 ttatcagcag ttataccaac aactaatcct acatcaactg caatattcaa atccctaata
      901 gcactaaaaa ctagaaatgg tataattttc tctcctcatc caagagctaa aaactgtact
      961 atagaagcag ctagagttgt acatgatgca gcagttaagg caggagcacc aaaaggactt
     1021 ataggttggg tagatgttcc ttcgattgaa ttaactaatg ttgtcatggc agaggcagac
     1081 cttatattag ctactggtgg acctggaatg gttaaatctg catactcttc aggtaaacca
     1141 gctgtcggag ttgggcctgg aaatgtacct gcaataatag atgagagtgc agatataaaa
     1201 atggctgtaa gttcaatctt agtatcaaaa tcattcgata atggtatgat atgtgcttcc
     1261 gagcaagctg taatagtacc agaaaaaata tatgaagaag ttaaaaaaga atttaaatat
     1321 cgtggagcac atttcctaaa taaagaagaa actgaaaaag taggaaaagt agtaataatt
     1381 gatggttcat taaatgccag aatagttgga caaccagcac atgtaatagc caaaatggcg
     1441 gatgtagaag ttccaaaaac agctagaata ataattggtg aagtagaatc tgttgaatta
     1501 aatgaacctt ttgcacatga aaaactttct cctgtacttg caatgtacaa gtctaaaagt
     1561 tttgaagatg cagttgctaa agcagaaaaa ttagttgcag atggaggcta tggtcataca
     1621 tcttcattat atgcagactc tataaatcat ccagagagag tagaaaagtt tgtaaatgct
     1681 atgaagactt gtagagtatt agttaatact ccatcatcac aaggtggtat aggtgattta
     1741 tataacttta aattggcacc gtctcttact cttggttgtg gttcttgggg tggaaactca
     1801 gtatctgaaa acgttggagt aaaacatttg cttaatatca agacagtagc tgaaaggaga
     1861 gagaatatgc tttggttcag agcaccagaa aaggtttatt tcaaaaaagg atgtttaggt
     1921 gtagcagcaa gagaatttaa ggatgttatg gataaaaaga aagcatttat agtaacagat
     1981 tctttcctat ataataatgg atatactaag aaattaactg atttattaga tgagatggga
     2041 attaagcata ctacattctt tgatgtagct ccagacccaa cattagcttg tgcaagagaa
     2101 ggagctaaag ctatggctga tttccaacca gatttaataa tagctgtagg tggaggaagt
     2161 gcaatggatg ctggtaagat aatgtgggta atgtatgagc atccagaagt agatttccaa
     2221 gacttagcta tgagatttat ggatataaga aaaagagtat atgtattccc taagatgggt
     2281 gaaaaagcgt attttgctgc tatcccaact tcagcaggaa ctggttcaga agtaactcca
     2341 tttgcagtta taactgacca agattcaggt gtaaaatacc cattagcaga ttatgaatta
     2401 atgccaaaca tggctataat tgatgctgat atgatgatgg agatgccacc aagattaaca
     2461 gcagcatcag gtgttgatgc tttaacacat gcattagaag catatgtatc tatgttaaga
     2521 actgaaccag ctgacggtct agcactacaa gcaggtaaaa taatatttga atatttacct
     2581 cgtgcatata aaaatggaaa gaatgataaa gaagcaagag aaaaaatggc aatggcatct
     2641 actatggcag gaatgtcttt tgcaaatgcc ttcttaggaa tatgtcactc tttagcacat
     2701 aaattaggtg cattccacca tgttcaacac ggtgttgcaa atgcattatt aataaatgaa
     2761 gtaatcaagt tcaattgtgc agaagctcca aataaaatgg gtgcattctc acaatacaga
     2821 tatcctgatt gcatacaaag atatgctgaa tttgcttctt ttgcaggtat taaaggaagt
     2881 acagaccaag aaaaagtaga taatcttata aaagcaatag atgaactaaa ggcaaaagta
     2941 ggtcttccta agactataaa agaggctgga gtagaagaat ctaaattctt agaaagattg
     3001 gatgctatgg ttgaacaagc ttttgatgac caatgtacag gtgctaatcc tagataccca
     3061 ttgatgagtg aattaaaaga gatatatcta aaagtttatt atggtaaata atatctattg
     3121 tgcaacatag gttctattgg gtttgtatat aaattattag atttgaatat aaatagagtt
     3181 ttattagaga tatgtataaa tagttataaa taatagatta taacttaaat tctgaatgga
     3241 aatgataaaa ggtcagtaat ttaaagataa ttttgaatat gtgtatttaa tcaattaact
     3301 ttaaaattag tcggaaaatt tttttattac atataatttt aaagcataat atataaaaaa
     3361 ctttatgaaa aaattataaa aatattcaga aaattctatt gactaattta tttatcatga
     3421 tataataagt ttagaaaaga aaaaaattgg ggcctattaa ggccccctta ctattttttg
     3481 atagatttat ttaaaattac tttctcattt tgatttttta tatttactat agagtcagta
     3541 taatccactt caaagttggc aaaagcagag aataaatcta tatctcttaa caaatgaatt
     3601 gtcatacatt gattgttctt atttagcctt agaatcaatg ctcttacaaa tggaaattgt
     3661 attctagaat taaataagtt agaaccatca gtatctatat ctaagctacg ataattaata
     3721 tctataaata tatctacatc atcattttct tctcttatta ttctgtagtc aaaatccaag
     3781 tttaaattta aattacctaa aatcaataac atttaaatcc tcttttctat aaatagtttt
     3841 agagtgttaa tttaagctct ccatctatta tagatataat tctatctgct tttctagcaa
     3901 tattttcatt atgtgttatt attataaggg tttggttata tttttttata gaacttttta
     3961 gtaaatccat gacttcttct gtagttttac tgtctaaatt tcctgttggt tcatctgcta
     4021 ggattatact tggttttgca gataaagcac gtgcaatagc aactctttgc tgttgaccac
     4081 cagataattg gttgggaaga tgatttttcc tttccttaag ccccaataaa tttataaggt
     4141 cttcaatata ttctttatct atttttttat tgtctaactt tagtggtaat tctatatttt
     4201 cctttacatt taatacagga attaagttat actgttgaaa gacaaatcct actttttgtc
     4261 ttctatatct tgctagttct ttatctgaaa ggcaacatat atctttacca gcaactttta
     4321 tagtaccatt acttggtctc tcaagaccac ctactaaatg tagaaatgta cttttcccac
     4381 ttccacttgg cccaattatt gcaacaaatt cacctttatt tatttttaaa tttgcattct
     4441 ttagtgcatg tacagatgtt tccttttttc cataaatctt acctaagtta atagtttcca
     4501 atataggcat aattattcct cctattctgt aatgtttata gcttcaacta tactaatttt
     4561 atttatcttt cttgatggaa tatatgtagc tagaatacct acaattatat ttgctacaac
     4621 aactagtata tatattttgt aatctattga aaatcccaat ccatatgata caaagccctg
     4681 catataatac attttaaatt gtattataag tcctgacacg atagtaatta tacttgagag
     4741 tacaccatat aatattcctt cataaagtat catattttta aatcctctct cagagatacc
     4801 aatagctctt aacattccaa attcactagt tcttgaagtt aagttataac ttatgttgtt
     4861 tattatgtta agtacactga ttatgaacat tattgctact atgccataac tataaatcat
     4921 agttctagat gtcatcttat cagaattttc tttttccacc atcatatcta ctgttgtagt
     4981 tccaggaact tcacttccaa ttttacctaa aaggttattt atttttttct tgtttgcatt
     5041 ttcattaagg tctgcataaa ctaagttata cttatctaca ccagttaatt tttttaggta
     5101 ttcgctactc gttattacat ctacactatc atctccagag tacataccat tatctgcaaa
     5161 aggataactt ataatagctc caactttaaa ttcatattct aagtattcat aattatcttt
     5221 tagactttca taaagccctg tatccatccc accatttgga tatttgactt ttatagtatc
     5281 acctactttt atatctacag ctggtgtccc ttcaccagga gtaaaagtct ttgtgtattt
     5341 ctgtgtttta gaaatttctg gtacatatac aatagctaaa ttttcttttt tcattttttt
     5401 caagtttata tttccactta ctaagtattt ttctaatgac tttatcatct catcattata
     5461 accttttagc ttttgcttta gtgtatattt gccagtagtc ttatttttta tgaacagagg
     5521 atttagctta taataaggag ttgaatttat agcttcgtag taatctaatc tatttatttt
     5581 atttacctct attcttgtgt ttaagatact agcagttttg actttgtcaa ttccatctat
     5641 attttttatt ttatctatct gactatcact aaaccctttt atatctttaa aagaagtatt
     5701 gttaccagtt tcattgagat aaacatttga tagaataaaa tctgcattca tatatgtttg
     5761 ttcttgtacg gatttgtttt gcacatctaa aaaagaatat ttataattgt cttttatgac
     5821 gattatacct cctatactca tagataatac aattatcatg aacccctttt tatttctaaa
     5881 gatatttttc gcagatatag attttgttac tgacatattt aaagttaatt ttgatattaa
     5941 ataattaact ttggttacat ttttatcaga tccaaaagtt tttctgatag catcaatagg
     6001 agaaattctt cttattttta agtatgtaaa gaaacttata attagcatta ttagtattgt
     6061 acatgcaatt gataagagaa ttattttatc tggaataaca aaaggtgtaa catttatatt
     6121 tccttcaaat tgaatatttc ctacagacct attaaatatt tgtgcacctc ccatacctat
     6181 acatatacct ataggcattg ctattagagc aagtatgaaa agttcataaa gcataagttt
     6241 gaaaatccta aagttggtgg aaccaatagc tcttaagatg ccatattcct gtactctttg
     6301 gtatattgat ataacataga tactatatat tacaatacca gcaaatagac tcatagcaat
     6361 tgcaatgtat ttacttgaat tatctaaagt accgtttttc atagtagatt ctataagcat
     6421 tgagtttctt cctatacttt tctcatctaa catagcattt tttattatat tgtctatgtt
     6481 tgtatttata tcactgcctt cattaaattc aatataagtt gtaaaattat tcagttctga
     6541 ttcattgaga ttagaaaaaa tttcacattg tccccttttt ttctctataa atctatcttc
     6601 aaggattcca acaactttaa aagtttctgg attttctttt tgatataatt taaaagtaag
     6661 gttttgattt atctctggtt ttaagcccat actatttaaa atccatttct cgactaccac
     6721 ctcattgcta gcttttggaa atcgaccttt tataagttta gaatgactag tcaaataatt
     6781 tttatttgca tatagtatgt ttataggtaa tttttcatta acatctgtag atgcatagta
     6841 agatgttata cccagatttt taatatcttt gctagatttt atggacttta attgattttt
     6901 ctttatattt ttaaagtata catggtcagt tccaagctct cttttcaatc tatctacatc
     6961 tgcttgctga gcacttcttg agagggtacc aataccaaca acgagtgatg tagcaagaat
     7021 tatactcaca acaattgcta aagacctagc tttataactt tttatatacc ttagtactat
     7081 tttcaaatta tctttcatat ttaccacttc ctttcttaac taaatcaatt atatatttat
     7141 ctaaaatata tagcaaagta agtattttca agttttaagt agttaattgt acaaattcat
     7201 ctgtattttt acaagtttaa ttaatatata tgtaaatttt aactttttac ataatttttt
     7261 taaaatgata taatccctat ataaattgta gaggggaggg gaatcatgga taacaatttt
     7321 gtatttccta tagtaatact aactttgttt atatttagca atcttataat gaataagtat
     7381 aaattttaca aagaattaga catattaaaa agaggcatat taacattttt tatatcgtgt
     7441 tttgcattga ttttatttat ggagggcact aaatatatac aattaaggtt aggatatagt
     7501 tttttacttg aaggagtatt aaatattata ctttttttgg ttttaattat tttaagtttt
     7561 tatacaggct ttaaagttat aagattgata aataataata atgaacagga atataaatta
     7621 caaaaactag atagtaaaat aaatcataag gataatataa ttatcaaatt aagaagtcaa
     7681 aaacatgact atttgaaaca tttgcaagta gtgtattctc tattaaatac tgggctagat
     7741 gaagatgcca aagaatatat aatgaatata tcaaatagct ttaaatcaaa aaattcaagg
     7801 tatggaaaag tatcttattt agatgctata gcttcattaa aatacgagga atgtcttgaa
     7861 aaggatatat cttttgatgt ctacattcaa gattttatgg ataatttaga gattgaacct
     7921 aatgatatga gttcagtact attaaacata atagataatg caatagagtc tttgtctact
     7981 ataaaaaaag aaaagaagta tataagatta catgcatatg aagatgaatt tcagtatatt
     8041 atagctataa aaaataatgg tcctaaaata cataatgttg aaagtatatt ttggaatgga
     8101 tttagtacta aagaaggaca agatagggga tatgggctac atttagttaa aaatatatta
     8161 gataagtatg attatagtat acttgtaaat agtgatgatt ttttaactga atttgtaatc
     8221 ttaatcccaa aatattatta gttaggagga gaaaagtcta tgataaaagt tttgatttgt
     8281 gatgatgata agattgtaag agatgatata gcaaatatag ctaaagagtc tggatatgta
     8341 gattatgtta aaaaagttaa ggatggtata gaggcaattg aatttataaa aaatgagaaa
     8401 atagatttat tgattattga cattgatatg ccatataaaa atgggattga ttctgctgaa
     8461 gaaattcttt ctatagataa ggatatacat atagtatttg tgacgggttt cgctgattat
     8521 agtcttgaaa gctttaaagt gcatcctata gattttgtag ttaaaccatt taaaaaagaa
     8581 aaaatacttg attcaattaa catagcaata gaccatatta actcccataa gattgctaat
     8641 aataatttta tagaagacac cctttttgta tataaaataa ggaagcagat acatatgatt
     8701 aattttgatg atatagttat gtttgagaaa aattcaagag caattaatct acacactaaa
     8761 gatgaagata taataaagtt ttatgagaac tttgatgatt taaaaaaacg cctacctcct
     8821 aatttcttta tgacccatag acaatacata gtaaatctaa gatttataca taaggttata
     8881 cctataaata aatcttcatt agagataagg tttataaatt ttcaagaaaa tgccatatta
     8941 aacaaatctc tagaaaaaga ttttttatat agattttata gggttaaaag attctagtga
     9001 agatagaaga aaaatacttt ttgtgtgata taataagtac cgtaaagata atgtataaga
     9061 gaagtttata taaaaattat ttgtaattat gatttaatct atataaatta cagtatagta
     9121 tatattggac tttctaattt ttttaagaaa gtccaatata ttttagagat agtttttata
     9181 cttataaatt acttaagata ctagggtctt taatcttact atcttcagca agtaatagta
     9241 tcttagacat aatctcagca gttttagggt cttcatcagc gaatggaagg aatatcttac
     9301 ctctactttg agaatgtata ggaagtatat tcaaagcacc catccctttt ttatgtacaa
     9361 taccagaacc catatgcaca gaatactcac ctaaattacc tgctataaga gcatgagagc
     9421 cttcaaaatt gacattgtta atttttaata ataataaaag ttctttagca attgctatac
     9481 gcatctctac agtagaatgg ctagtttcag ggtcaacacc accagcatga gcgacactta
     9541 caacaaggtc tatatcacgc ataacttctg agaatagaat tggaggtata gaagctaatt
     9601 ctaaactttt ataagttttt ctatcaaaaa attctactgt ttcaatagta ggaggctcta
     9661 tatctgctgg tgaaaaccaa tctgcaagtg caaacatctt tgccactata ttttctttat
     9721 aaaatacttt ctgtaatccc tcttcataat cgacagtcca aagctgattt ctaagaagtg
     9781 ctacagtttt ctttggctga atttggtgac cagcatatct gcgagatata gttttttcag
     9841 ataattcatc actgtttatt ctataatact cacggaatac ttgcttaaat ggttgaacaa
     9901 tttgcttact aaataaatca tgttggaact cactccactt accagattca aacaaatgaa
     9961 ctggatgtgc aagttttaat ttattttttg ccgtcaactt ataagtttca ccttctatat
    10021 tgcaaataaa gaacttagac ttatcattat aaacatatcc aatattatca tcacataccc
    10081 atactagatt tttaatcaaa gggcagataa ctggattttt atagatattg gcaatttctt
    10141 taactgtaaa tactatttca tttttcatag cttgttctaa actctgtttt gcacgagaat
    10201 actgactctt taaatctttt tggacagatt taagttcaag tacatatgga tgtttagcaa
    10261 tagcttttgg tatactcttt aaagacttgt tgcctttttg aactttagta gatgcttttc
    10321 cgttttcatc aacatctatc caaattgaag taccatcaat atcttttggt ttaaatagat
    10381 gagcaacttc atttagtttt tcagtctcaa gagcccacat catacgattt acatctccaa
    10441 atccagcact tctagctaga ttttctagcg ctatagtaca agcttttgat tcactttcac
    10501 gacgttgtgc accaaattgc ttgctttctt tagcaaactt ttgaataaat tcataacgga
    10561 aagttgcttc ttttaggtct ccttttttca taggaagtaa agagaaactt ctcaatttat
    10621 cttgatttct atttgtttca atttctttca tcaacatgtc tttatcaagc ttaccaagtg
    10681 tagcatcagc atagagttgt gcacgtctat gagagttacc accactagtt atatatttag
    10741 ctgacttgta aagtatattg aatctttctt ccccaatagt tttatatgaa tctaaaaacc
    10801 aatctacatc aaatgcacca tcaatgaaac tacgtggtga aataggggag aatagagcaa
    10861 cctctgattc tttttgtgca gagaagcctt catttatatg tgcatggaag taccaaattg
    10921 tacttttcag acccttccag tttaaatatt tttcaattat gtttacccat tgaggggcat
    10981 acatagcaga ttctatcaat cttaactcag taatgtcggt atttttaagt aaacttttta
    11041 atttttttga atcatcttct ttagtaggat agcaattttt aagtagagaa cttaaaacat
    11101 ctttttttga ataattgcta ccatatgaat atcctctctg gaaagtttct ttaccaagag
    11161 cgaccaaaat atttacaaaa taatttatac cttcaaagta ttgtatatta ttagctagat
    11221 gagacacttc tgttggcata tcacctctac gtgattcaat ttctataatt cggtttgtaa
    11281 cagtttttaa attatcttta agccaagggt acttttctaa tgtgtcgcca gcccatctag
    11341 gatttgtcaa tgttcttatt atatttgatg cgttgtatcc acttatcatt tctctattaa
    11401 cttgctcttc agtcattaat cctaattcat gtgcacgagc aaacacattt atgctagtat
    11461 agaaaggaaa cttatattct agcaactgat aatttgaaaa cgtagtgtag aaaaacttag
    11521 taaaagaaat atcatcataa ataaacgaat gtgctttatc aagccagtag tttaaaatag
    11581 gggcatttaa agcagggcag tattcatttt gtctgtaata gtttttagta aattcaactc
    11641 tttgtttttt acattgttct atagtcaata agtttctaag tttatagtat atttctaaac
    11701 aatagttaaa tatttcttta tggtcaaact catttagtaa aactcttaaa agttttcttg
    11761 taagtccatt aaatttaagt ttttcaagtt ttgtatatat tttattttgt tttttagagt
    11821 caaggacatt tgaatatata gatgaaaacc aacttttttc tgtttcatta tatccacatg
    11881 tacttatact ataaaataag atatcaagta ttaatttgta atctaagtca agttttttac
    11941 tagtttctct ccaaagttct gctaatggat aattatcaag agtatcatta gaaactttat
    12001 atttaatagg agtcaagtta taagtagaat aacctaaaag tactttgtct acattacctg
    12061 accatctttc aacttcatat tcataatctg cattttcagt aataagctca tcaaattttt
    12121 cataaacttt tattatttta tttatatccg tatcgagaat tttttttgct tctttttttg
    12181 ttgctacaga aacagaatcc tcacgagtag ataaacttat atttgaaata attttattaa
    12241 gctttgatga gctattagaa tcatctttaa aatcaaattg ttctggaatt tgaactttgt
    12301 tttcatggtt atatattcca aaaccatttt ctttgcagta atcatttttt gctttaccta
    12361 acaaattatc aattagtatt tgaacttgag atgtattctt tttagattta tcaatatctt
    12421 ctataagtaa aacaagctta ttatatagtt cttgtctagc agtattgtct tttaataagt
    12481 ttacaatttc aagacctcca aggcattttt gagaatttga agattttatc agtgaagaag
    12541 caatattttc caagtttgaa tcatcttgtt caagtaaaat ttttattact gtttgtctaa
    12601 tagagcttgt ctttaaagac aatagattgg ttatcttatc taattctaca tctgttagct
    12661 caagctttct aagtagactc aataccgttt ctctattgga aacactctta tcacttaaac
    12721 attccaataa aaattcacgt tgtctatctg tctttggttc atttacaaaa ttgactataa
    12781 gtgaagctct taaatctgaa ctcataagat gacaattttc cataagcaca tctataaatt
    12841 gagcattcat atcgtatgct gttaaagtca tcatacattt aagtatttca tgagaagaaa
    12901 tttcaatcca agtccatgga aatacacttc ctgaaaatga ttttgtcttt gaatttaaaa
    12961 tttctaaagt atgttttaaa ctttcaaatt gttcttttct agcatcaaag tctttgtcaa
    13021 taggagtgtt tgacaagtca aaattagttt ctctgttttg ccaactatag tagtagccaa
    13081 cagaaccttc tacatagaaa tttgtaatta cccatgctag tatctctaaa tcatcaccct
    13141 taatgttttt agatgctata gaatgtttaa aatatgtact ttctgtatgc gataaaaagt
    13201 aaagagctac aagtttttta tatttttcct gacaagaaag taagttttca ataagagagt
    13261 aagagtcata tatgttgtaa gttgcagtag cccacaaggc aaaataaatt tcaagattat
    13321 cattgctatt aattgattct atacggaact tttcatcagt caatgattta tatgaaagtt
    13381 ctaaacattt acgtattatt ccaggttttt ggtctgaaaa accaagtcct gtccatgtat
    13441 ccaaggctct tataacagaa ctaaatcgct ctaaattgtt gtccaaaata gtttttaaca
    13501 tgtatattga tgcagaaatt gtaccctcat ctaaactctc tacaatttgc tgtctaagtc
    13561 cttcttgttg tttggctgcc aaaaggagtt tagaaagcat ttcatagcat ttatcactat
    13621 gactcttcat gataccaatt atcatttgtc ttgtaagtag agcagtttga ttttctccaa
    13681 atattacttc ttctaaagca cttattactt tttgatttcc tttgtctatt tctagtgcta
    13741 ttttatcact cattatagag tcatagtaca agaccttatt tggaagagta agataatcta
    13801 taactgaaaa atcataataa attaaatcaa catagtttga aataaacctt ataatacctc
    13861 taaaataatc cacaagttta tttgagcgat aacctttacg ataatatcct cctgaatatg
    13921 tataatccat ctttctttta attaattggc aaagttcttc tacttgttca gaagtaaata
    13981 ttaattctaa tgcatttttt aaaggtccag aaaggagctc gtccatattt ttaatttcgt
    14041 agtagtggca attgtagtat ttctttatca tatttaagaa tttgtcttca ggttctctat
    14101 aatagtatga actattttct atgcaatccc aaagagactt tgctaagtcg tagtactgtt
    14161 ttgaagaaga tttagtaaaa ttatttttaa aattttcaat tattttagga tttttttcta
    14221 ctctagtacg ttctaacatt tatgtacctc caaattattt attttaaaac attcttccag
    14281 caagcaaggt aagtcttata aaagtaaata tatctccact tttcagattt atagaggaat
    14341 cgagtttttc aataacatct tcatttataa gcactttgta gattccatct tcaaatgcct
    14401 gtaacgctac ttctattgcc ttttctacag attgtttatt ctcattgtaa atagagccaa
    14461 atccaacttt tccaatatca gcttgagatt caatttcttc attagttaag aagtttatta
    14521 ttgatttttc tgggattttc tcattatatt caagaacatt tttagataca atttcagaga
    14581 tagcttcttt taggcaattg atgttgtcag atacatcaaa aggggtaagt tctagcatag
    14641 gtttgcgttt gccaacagcc ttaactctaa aataaatttg cataaaatca cctctcaaaa
    14701 tattaattat gtatttagaa atttaaaatt tatctatttg ttatattata tcattttgtg
    14761 aattattaat gtgaattatg gaattatttt acaaaaaata gaaaaaaagc tatcttaaag
    14821 tctaaaaaag caataaaaga taacttttaa ctataattat atagaattat aactgtacat
    14881 ttattaaatt ttaattttag aattattttt gataactatc tttttttatt tataaatttt
    14941 gctcctaaat attttttgat atcttcttca ggagaaaagt catcaataag tatttctttc
    15001 ccagtgtctt caaatactac aagaacttca cagtcacctt gtaagaaaaa ttttctaact
    15061 gtatcttctt taacttctct aacttttatt acattctttt tttctttttc aaagtctttt
    15121 gtgtaataac ttcccatcat attaattatt tttgtatatc tattcataaa atacctccat
    15181 atgcgattaa atttaaaaaa tatgttataa taattgtttg tattaactta ataattataa
    15241 caaggagtaa taataatgac tagtataaaa aataaagata ttttaaattg tatagattat
    15301 tccattaaaa ataagctctt tgacaaacta aatgatgtat ataagtcctt gccagtagga
    15361 aattgttctg gatgtggaaa ttgttgtatg gagtcagtag gtataaattt aattgagttt
    15421 ttgaatatat tttgttatct tgaagataga gttgatttaa aaaaaagctg tataagtaaa
    15481 atattagatt attattttga ggagtataca agaaagaacc catgtccatt taaagatact
    15541 aataatagat gtttaatata tgaagttaga ccattaaatt gtaggatgtt tggacattgg
    15601 aaaaaagagg attataataa aaatttagat aatgttattg agaaaaataa taactataga
    15661 gagttaatga aaaagcaata tggatttgaa ataaatgatg aagtagtaaa ttacaggata
    15721 gattattgtg atagatttat tccaaataaa gattatttaa gtaaatctaa gagattaagc
    15781 ttttttgatg agcttatgat attagactca aatatttatt caagtggaaa tatagatata
    15841 gactttaggg atagaggtat agttgaatat tttatagagt cattacttta tagaaattta
    15901 gcatataatg tgaaaataag gatatctaaa gaatacaaaa taagaaaaag aactatagat
    15961 agaataaaaa ggattgttct tgtatagttt tatattagta agtaataaat tgtatcataa
    16021 atattgtcaa aatgaggtga agaaggtgaa tcttacaaaa gtaaaaggaa ataccttttt
    16081 tataaaaggt ggcacgaata caggaatata tgtatttgaa gataacacag cacttatgat
    16141 agacccaggg ttatgtggtt caagacctag gagagtaaat aaagtattag atgaaaataa
    16201 tatacaggtt agatatatta taaatactca tggtcatgat gaccactatg gagcttgtaa
    16261 tcaatttaaa gaatattata aagatgtgtg tataatgtca tctgaatacg ataaattata
    16321 tatagaaaat ccagaattgt tttcaaagta tattgttggg ggaaagagca atgtatttat
    16381 ggataatatc ttaaaaaata aaatgttgga tgatataaaa atagataaat ctatagaagc
    16441 tggaaaaatt gaattaaaca atgaaatatt tgatataatt gaatttcagg gtcatacacc
    16501 tggtagtata gctgttttga cgaaggataa tgtgattttt gttggcgatt tattgatagg
    16561 agatgaaatt ttatcaaaat acgatttctt gtttctatat gatatacaag aacaaataaa
    16621 ttcattagaa aaattaaaaa atatagattt tgagtactta gttttagggc atggcaagca
    16681 agttatatcg aaagaagatt cttataaatt aatagaaaaa catttgaatg ctttaaaaaa
    16741 atatttatat caaataagag agttgcttgt agaaccgaaa tctttagaaa ttttattaaa
    16801 aaacattata aataacaata atttaagcaa taattataaa gagtatcatt tttttaaatc
    16861 ttcgttagta tctgtcataa gttacttagt tgatttagaa gaaatagggt atatattgga
    16921 aaatggagaa ttgctttact atacaaaaac aaaataaatt atgataaaat aaagaaggtc
    16981 ataaaaaaca aataaagggt gagcaatatg gaatacgaaa aatggaatga gatactagca
    17041 ccttatgaac atgcagtaga ggaattgaaa ataaaattta aaaatataag aaaagaatat
    17101 ttagcaaaag gtgaatattc tcccatagag tttgtcacag gtagaacaaa aaaaatatct
    17161 tccataatat ctaagttaaa aaggataaat gcaaaagata tagaaactga aattgatgat
    17221 attgctggta taagaataat gtgccagttt gttgaggata tatatgctat agttgatttg
    17281 ataaaagtaa gaaatgatat gactataata ggagaaaaag attatattac aaattacaaa
    17341 gatagtggtt atagaagcta tcatgttata ataaaatacc ctataaactc cattgcgggt
    17401 tcaaaggaaa ttatatgtga aatacaaata agaactcttg caatgaattt ctgggctaca
    17461 atagaacatt cattaaaata taaatatgac cattacatac ctgagactct tgctgaaagg
    17521 cttagaagag catctgatgc tgcctttctt ttagaccaag aaatgagtga aataagagag
    17581 gacataatga aagctcaggc tatgtaccaa atgaagtcta tagctattag agatactcta
    17641 aatagaatac aagagttata tgacttgggt gatacacata aagctatgca gtaccaaaga
    17701 aaacttgata gaactgaaac agataaaaat ataactgaaa ttttggaatt aaaacaagaa
    17761 atagatatat tattagagca atataaggat actaaggtag atgataaagt agttcagtaa
    17821 aaactacttg tagaaaattt gctaaatatt aatggggctg cctcttaatg gaaaataatt
    17881 tctaaaaaga gacagcctat ttagtgtaat taagaaagga atgatattat gagtttgtat
    17941 gctataggtg atttacattt ttcaacatca gtcaataagc caatgaatat ctttggaagt
    18001 aattgggatg gtcatgaaaa gaaaattata gataattgga aagaagttgt tgaggaagaa
    18061 gatatggtct tagtactagg agatacatct tggggaatta atttatccga agctaaaaaa
    18121 gatttagata taataagcaa acttccaggt cagaaaatac ttataaaggg aaatcatgat
    18181 tactggtgga caaccgttac aagtttaaat aagctatatg aagacatgcg ttttattcag
    18241 acaaattttt atgaatataa agattatgca atttgtggag gtaggggctg gatatgtcct
    18301 aatgatgtta aatttgatga gactgatgaa aaagtttata aaagagaaga acatagactt
    18361 agactatcat tagaatctgc tcgtaaaagt ggtcactcaa aaataattgt gattactcat
    18421 tatcctccta cgaatgataa attggaagaa tctttattta caaagttatt tgaagaatat
    18481 aatgttgaaa aggtgattta tggtcacttg catggtaaag aatcttttaa aatgggattg
    18541 aaggggattc gaaatggagt agaatataca ttagcatctt gtgactatac agaatttaat
    18601 ttaataaaag ttcacgatta aaaaacataa attggtaaat actataagat acatgattaa
    18661 aaataaatat ttgagggatt tcggttttga gaaaggagac acgacttatg aggtggatat
    18721 tagtttttat atttttatat cttattcctt tagtagtgat attcagaaat tacaagaatt
    18781 ttaagaggtc ttgtatctac agtagtattt atgtggtatt agctacaaca ataatgataa
    18841 gtaatattta tatgagtgga cttaataaaa taaaagagtc tatgtattat cacaattata
    18901 tttctgatga gacatatgat gaaaagtatg tatcaaattt taaggaaaaa gaaagtactg
    18961 atttaaaaca ggataataaa aagaatgaag aaatatcaaa taataaaaat ttaaacaaca
    19021 aacaagatag aaatatacaa aataaagaaa gtaatgaaga aggaagtaat gatataaaag
    19081 aaaagaataa ttctgatagt aatgtttcag tgaataataa atcagaaaaa caagaagata
    19141 atacaaaaga aaataataaa tatacaagta aagaaaaaaa tagtgaagat ataaaaaaaa
    19201 tagatatgga aagtatagga atttttaaga aagaaattta taatatagaa agagcagctt
    19261 tagttccaat gagagaatgt ataccttaca ctaaggatat agcaaaaaat ataactaaat
    19321 tatctagtat aaaaaaagat gttacaaatg ccagaaacaa gtgtaaagaa gttgtaaaag
    19381 aatatgaaaa tatgcagatt ccagaacttt ctaaggagaa gtatacagaa acattgagta
    19441 atgctagaga tgacgtaaag aaagcatatg agcttagaga aaaatctatg gaaagtgctt
    19501 tgaaattaat aaatactaaa agccctaaat atatagggaa gataacagaa tatcttgatt
    19561 tatcagataa gcagatagaa agttttaaaa atagattgaa cgatttaaaa gaagaaataa
    19621 ataattcaga aacaaataat attaattaat aagatttaag gatataagtt aaaagggaga
    19681 ttatgatgaa taaacagagt ataggaaaac taaatatgtt ttttatgggg attactcaaa
    19741 gaaaccttga taatagggat ttttttattg agttagaggt gatttttaaa tctggaagaa
    19801 aagagtttaa aggaattgca atagaggaag ataataaata taaatttaat tttaaaggaa
    19861 aatcagattt atatacgttt aatgagttgc ttaagaatat ttctaaagag gcagaaaatt
    19921 atgatggatt agtatttaaa tatgttgagc gaggaactat tgttgtaatt gaaggagaca
    19981 ataagaaggt aaatgtaaaa tatttagaca ataaggaaga agtacctaaa atagatgaat
    20041 ttacggcatc tcaaataaaa aacagagatt attatgtaaa agtaggacaa gcaaatgcac
    20101 ttttaaaaga aattggagta cttacaaaag atggtaagat aaaaaatgat aaaataagaa
    20161 aatacaatca gatagaccat tttgttgaat tgatagatag tattttaaaa gaaataaagg
    20221 ataaagactg tataactatc ttggattgtg cttgtggaaa atcttactta agctttgtct
    20281 taaattttta tataaaagaa gtattgaaga aaaactgtta ttttatagga atagattatt
    20341 cagatgtagt tatagaagca tcaaaaaata tggctaaaaa cttgggttat aaaaatatgt
    20401 catttataaa agaggatttg actaattata cacctaatag ggatgttgac cttgtaataa
    20461 gtctacatgc ttgtgataca gctacagata tggcaatagg tctaggaatt agagcaaaat
    20521 ctgaagctat agtagtagta ccatgttgtc ataaggagtt attagggcaa tatagatatg
    20581 aagctatgga accaatatta aaacatggtg tatttaaagc tagatttgca gatttaataa
    20641 ctgatggttt aagaacattg ttattggagg gcaatggata tgatacttct gtagtagaat
    20701 acatatctcc acttgataca ccaaaaaatt taatgataag agcgataaaa actaaaacga
    20761 ataatgacaa agcattaaaa gaatataaag aactgaaatc acaatttgga gtggaaccaa
    20821 ccttagaaaa acttatatat tagttaaaaa tgtaaaattt acgaaaagct tgcttaaata
    20881 tgcaagcttt ttggtattat ataggtatag tcatatccag agttttgatt tataattaaa
    20941 gctgtgctat aatatttgat taatcaaatc aataaatgtt acatggaggt aaaaatgaac
    21001 aaattgaata tatgtattga tatagatgga acaataacaa gcccttatca ttttcttcca
    21061 tacctaaatg atatctttaa taaaaatata actgaagcag agtgtataac acataattgg
    21121 gaagaattgt atggttcggg aataagagat gtgtatgcgg agtttaataa taagtatata
    21181 cactcatatg atgaagcaaa gattgtagag ggtgctacag aggtaattag cacattatct
    21241 aaaggacata atttatcttt tgtaacggct agacatgagt gtttaactga tgtaactaaa
    21301 aattggctat caagacaagg attttcagat atagatgttt acttattagg aagtgattat
    21361 aaagttgaaa aggcaagaga actgagttgt gacatattta tagaagataa tcctttaaac
    21421 tcagtgcaac tagctgatga tggtgttaaa gtaatacttc tggatactaa ctataataaa
    21481 gatgttaaac atcaaaatat agttagagtt agtaattgga tagatattga aaagattata
    21541 aaacaaggta tttaaagatt tgtagattga aagggggagc atatgataga tttaaaaatt
    21601 gaaaatagaa aaggaaaaat ccatgtaaag agcagtgaaa taaaagacat tttagaatta
    21661 cgtccagact tcgaatatgt acaagatata tcaaatacta taaatcaaga aaatatattg
    21721 gtatttgatt gccagttgac aggaaattct tttgatatgg atgatttaga tatagaagaa
    21781 atattggaag agttaggtga agaaatagat gagtcttatt tcagtgtttt atttgaagat
    21841 gtaagagcgt atttaaaaga tgctactgat gagatagaag cagacttaca ggataattac
    21901 ttatttgata atttgagatg ttattttgat atatacaata taaatcaaga atttacagat
    21961 tttaagtttg tatttttagt ttcttttaaa gatataaaaa tttcttcatt agcaaaccta
    22021 gctaagattg tttctaagag acagcttata ggtgcatcta agttttatag ttaaaatgaa
    22081 agattattat aataaaagct agtaaccttg taaaaatata ggttactagt tttttattta
    22141 ttcattttca caaaatttca gaaaactatt tacattctaa aaaaagtaat gtatattaaa
    22201 cataatgtac attataatgg ataaaaagtt tctattaaat tactaagttt atttaataat
    22261 caaaataatt tatcttatat tagtatgtat tagggggtat ttatgcaaag tttaaatgaa
    22321 ataatcgctg aaaatttaaa aaagataagg aaagaaaaac atcttagttt agacaagatt
    22381 gcacaactta gtggtgtaag taagagtatg ctatctcaaa ttgaaaagtg tgaggtaaat
    22441 cctactatat ctactttgaa gaaaataact aatgggctaa aaatctcatt tacatcattg
    22501 atggagaggc aggaaagtga catagaattg attcaaaaaa gtgatataga ccattttatt
    22561 gaagataatg gaaagtatat aagttatcca atatttccat ttgactccaa aagaagattt
    22621 gagatattta tgattgaaat agaagaaggt ggaaatttag attcaaatgc tgaacttcca
    22681 ggaacacaag agtttataac tgtttttagt ggcgaagtaa ccattaaaat aaatggagaa
    22741 gattacattg tatctagtgg aaattctata agatttaaag ctgatgtatc acatatatat
    22801 agaaactcag gcaaaggtat agctaaaatg agtatggtag tatattatat ataaataatt
    22861 taatggaatt agagtgatat ttagatgatt ttaggtatga atatatatta tatttaagtt
    22921 ataggagtgt gatttatgga tgaataataa aaaagcagtt tttttctttt gcagtgattt
    22981 aaagaaagac ccagtagcca gtaatgtgat aaagtgttgt gaagaaataa tggatttaaa
    23041 tcaaactgat atttttattg atgataattt tgtattagag tttaaggata aaaacaataa
    23101 cttatttcat tttgtaaaaa caaaagatgt aataagtcat aattataaat attatcttcc
    23161 aattttaaat agacatttca gagattatga ttttgcagga gttgtaaatt ggcatgaggg
    23221 agaaaatgct ccagaacata tcctaacagc tcatacaatt ggagatgttc caacaggaga
    23281 atttggaaat tcaaatccaa gatactttaa aaatctaatc aatgctattg aggatataaa
    23341 aaatgaaaat ctacttgatg aatttactac attaacagaa gcaactcact ggtctggaac
    23401 aacatatggt gaagaatcta aattaattac agaatattct gtacctatgt tggatattga
    23461 gataggaagt agtagtgata gttttaataa tagtatagca atacaggtat tggcaaagtc
    23521 attaattaga gtatttgatt gtgatgaacc tttgaagact ttgttatgtg ttggaggggt
    23581 acattttgag aaatctttct cagatattat aaaaaataaa gaatataaca tatcaattgg
    23641 acatgtattg ccaaatcaat ggattgtaag tggaatgtat gatgatgaat ctggatttga
    23701 gaaactagaa aagtgtataa atagtattga aggaggaatt gattgtatag tttttcatga
    23761 taaattaaaa ggtacctata aagagcaatg ccgtaaacta ggtgaaaaac ttaatgtacc
    23821 tgtatttaaa cataaaatat taaaaaatcc aaaagactta cctatatggt agttttatac
    23881 agttaatata acaataagtc ggattaattt ttaagcgagg tcaaaatgat attatcttat
    23941 tttgcattat taattagagt agtgctatta gcttttgaaa gagtagttgt aagattatta
    24001 ggtgatgaag aaggagatat ttataaaaat atagcttcat catttctatt tttctttata
    24061 gggggagtat gtttacttcc atttagcata atggatagag ttagtgattg gtcgttttta
    24121 ataccatgtt atataagtag tttagtctat tcaattggtt cagtagcgta tgtaacgtct
    24181 ttagcaactg gggaagtttc acttgttact ccaataaata gtttaaattc attgttttta
    24241 ctgcttttat cagttatatt tttaggtgaa ggtttaagtt tagcaaaagt tgcaggaatc
    24301 ataattatga ttggtggagt gtttatatta aaaaaagtaa gctctttttt aaagaatgtc
    24361 tctgtaattt ttaacaattt accatgtaga ttaatgtttt tatacatatt tttgcagtca
    24421 gtaggaagag tattggataa ggcttttttt gtacaagtat ctcctatatt atattcaact
    24481 atactgtatt ttttcgtagg tttaaattta tttatctttt tagcatttaa aaagaaacaa
    24541 aaaataattt gtgagatttt tactaataaa aagggacttt caattttaag tggtgctatt
    24601 aatggatatt cttatttagc attattaatt gctttaaata atctagaact tagtatagca
    24661 gagccatttt ctcaagtatc tatgataata actttaatac ttgctcattt tatattcaaa
    24721 gaaaatataa aagaaaaaat accaggttca attttgatac taattggtgg gtggctactg
    24781 ttactttaat tgacataaaa aatgaattat aaaggtgcta ttagttagta tcagaaaatt
    24841 taaaaaagta ttgacaattc ttttaggcaa atgttaatat aataatacaa aatagtataa
    24901 atagaagaca tgttactggt aatgcaggca ggatcgaata tattgctttg atttttcaag
    24961 gtgtttatat aggttctgcc ttttttgcat cttgaatggc cattcataaa aaattatgga
    25021 gaaggagatt acaagatgaa ttataaaaaa actgccattg acattattga acaagttggt
    25081 ggttcaaaaa atattttagc tttagaacac tgttcaacta gactacgctt taagttgatt
    25141 gatagaagta aagtcaatca ggatgcttta aaaaaagtac aaggtgttat gagtatagtt
    25201 aatggggcac aatttcaagt tgtcattgga aatagtgttg ttgatgtgta tgatgaaatt
    25261 ttaaaagttt gccctttaga tacaaatgat agtactgtaa aaactgaaga aaaaataaac
    25321 ttaggaacaa gatttataga atttattatt aatatttttc aaccactgat ttttgctatt
    25381 gcaggagctg gtattttaaa atcactgttg atgttattag caatgtttaa tattttaaaa
    25441 tcagattcta ctatatatac attattagtt gctatttcag atgcaacatt ctatttccta
    25501 cctcttatgg tagctgtaac tactgccaat gtattgaaat gtaatcgttt agtagctatt
    25561 gccgctgtag gatacttatt gcttccagca acaacaactg ctttaagtga aggtgtcgaa
    25621 ctatttggat ttacaattcc aaacattgcc tataatgcac aggttttccc agctatttta
    25681 tgtgtgtctt tcttggcaac aatggagaaa atttttaaca agtattcacc aaaaccaatt
    25741 cgaactttct ttgttcctat gatgtctttg gcaattactg ttccaattac tctaactatt
    25801 ttaggtcctt taggatataa cgttggtaca atttttacaa ccattatttt attcttgtat
    25861 aacaaaatgg gattcttagt tgtaggatta cttgctgctt ttcttccatt tatggttgca
    25921 acaggaatgc acaaagcact aataccttat tcaattaata caattggaaa gttgggttat
    25981 gaagctttat atatgacatc ttcattagct cacaatattt ctgaaagtgg tgcttgtttt
    26041 gcagtagcct tgcgaacaaa agatgaaaca ttaaaacaaa cagcattatc tgcaggaatt
    26101 tctgccttga tgggaattac agagccagct ttatatggta ttactttaca acataaaaga
    26161 gcaatgttag gtgttgtatt ctcaagtgca atttctggta catttttagg attatttgca
    26221 gtaaaaggat ttgtaattgt tggaccaggg cttgccagta tgagtatgtt tattgaccca
    26281 aacaatggaa acaatttgat ttttgcaagt attggttttg ttattgcaat attaggctcg
    26341 tttattatta cactgattat ttggaaggaa gatacaaata cagtagagtc atcaattgga
    26401 gatgttgttg aagaagagct agaagaagaa aaagaagtaa atatcttagt aactccagta
    26461 gaaggaaaag taatagattt aagtaaggtt aatgatgaac tatttgcaag taagactttg
    26521 ggagatggag ttgcaattat accgaccaat ggaaatttat acgcaccttg tgattcagaa
    26581 gttgtgatgt tatttgaaac aaaacatgca attggtttaa gaacaaaaaa tggggctgag
    26641 attttgattc atattggaat aaatactgta agtatgaatg gagatggatt taaaacattt
    26701 gttaagacag gcgataatgt aaaagaagga gatttattaa ttcaatttga tttagacaaa
    26761 atctcacatg ctaatttaga ttcaactgtt atgattgtaa acaataatgg agcagattat
    26821 gcttataaag tgttaaacca gtcttatggc aatgtaaaaa aaggaagtat cttgtttgat
    26881 gtaaagggag gaatataaat atgagaaagt ttccagaagg atttctttgg ggaggagcta
    26941 cagctgctaa tcaatttgaa ggtggttgga atttaggtgg gaaagggtgg tctgtatcag
    27001 atgtagcaaa ggcacacttt gatgcagatg tgaaagatta taaatctaat aatgaaatca
    27061 caacaaaaga tatagaagaa ggattagcac atcctgaaga tgaagtaaat tatccaaaac
    27121 gtcatggtag tgatttttat catcactata aagaagatat tgctctaatg gcagaaatgg
    27181 gatttaagac atatcgaatg agtattgctt ggtctcgtat ttttccaaat ggagatgata
    27241 aagagccaaa tgaagaaggt ttacagtttt atgatgatgt atttgatgag ttgataagtt
    27301 atggaattga accacttgtt actatgtcac attatgaacc accattaaat atcgttttaa
    27361 actatgatgg atggtattca cgacaagtta tcaatatgtt tgttaggtat gtagaaacta
    27421 tctgtgaaat atataaaaac aaagtgaaat attggcttac atttaatgaa gttgattcta
    27481 tgattcgtca tccgtacact actggtggtt tagttcgaga ccgttttaag gataaaaact
    27541 ttgaggaagt tatttttcaa gctatgcatc atcaatttgt agctagtgcc cttgcaacaa
    27601 aaatttgcca tgagattatt ccaaattcaa aagtagggtg tatgttaaca aaattaacgt
    27661 attatccata tacatgtaga ccagaagatg ttttggcaac tcaacaaaaa atgagaagta
    27721 tttatgcata tagtgatacg caggtttttg gtgagtatcc agtatattta ctgtcgtatt
    27781 ttaaaaataa taacattcaa atagtaaaag aagaacatga tgatgaaatt atgaaaaagt
    27841 atccagtaga ttttatttca ttctcttact atatgtcttc ttgtgaggca gctgatacaa
    27901 ctggattaga tattacacct gggaatacgt tattagctgt aaaaaatcct tatttagaaa
    27961 tgagtgaatg gggttggcaa attgattcaa taggtctacg tatatctttg attgaattat
    28021 atgatagata cagaaagcct ttatttatag ttgaaaatgg attaggagct aaagatattt
    28081 taactgaaga taaaaaagtt catgaccaat atagaattaa ttatttaaaa gaacacttta
    28141 aatgtatgtt agatgcgatt atcgaagatg gcgttgaact ttggggatac acttcatggg
    28201 gttgtattga tttggtcagt gaatcaacga aacaaatgtc aaaacgttat ggatatattt
    28261 atgtggatgc tgatgattat ggaaagggga catataatcg atataagaaa gatagttttt
    28321 attggtataa aaaagtaatt gaaaataata gtatagattt taaatgacca atagaaggtg
    28381 agcaaataaa atgaactaca taataaagaa agttttgaac tcgagcgttg ttttagttca
    28441 tgacacaaag gataatgaat ttattttgct agggaaagga attggatatg gtaaaaaaac
    28501 aggagaatat atttgtggtt ccaatgataa tcaaatgttt gtccctgttg aaaatacaaa
    28561 atcaaaacaa tttttagaat taatggatga tattcctgtc gacattttaa agataacaca
    28621 ggaaataata gtagaggcag aaaagttatt gaactcatct tttaataaaa acttatactt
    28681 aatattagca gaccatttta actttgcaat tgaaaggatg cgtaaaggaa taaaaattac
    28741 aaatcgagta ttttgggaaa taaaaaatta ttatccaaat gagtttaagg ttggaatggt
    28801 tgcaatttat atggtagagg agagattggg cattcaatta ccagaggaag aagcagctaa
    28861 cattgctttc cattttgcaa atgctatggc ttcagatgga aattcatatg atacgattaa
    28921 gtatgccaaa gtaattggag aaataattaa tatttttgtt ttttctttga atagaacctt
    28981 agataaaaag agtatgcatt atatgagatt tataacacat ataaaatttt ttgtggaaag
    29041 atttttttca gatagtatgt taagcagtgg tgatgattta ttatttaatc aaatgaaaag
    29101 gtcaaatcca aaagaaatgt taattgcatt aaaagttaga gattttttag aaaagaaata
    29161 tggaaaaaag ttaacaaatg aggaaatagc tttcttggtt gtccatatcg cacgagttaa
    29221 gcaatagagt gaattacagc aatagagtaa attacagcaa tagagtgaat tactaatatt
    29281 atcttgtacg tctacatggt agaaaattga aagaaggtaa agtgtataaa gaaactgaga
    29341 catattattt tgttgttcat tatgtttatt ttatgagtgt atcctgttaa aaatttaagt
    29401 taatatttat aattaaaata tacaa
//
LOCUS       DAMJXI010000043        29389 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.045, whole genome shotgun sequence.
ACCESSION   DAMJXI010000043 DAMJXI010000000
VERSION     DAMJXI010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29389
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.045"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(167..1036)
                     /locus_tag="PC465_002485"
     CDS             complement(167..1036)
                     /locus_tag="PC465_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2649771.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
     gene            complement(1133..1990)
                     /locus_tag="PC465_002486"
     CDS             complement(1133..1990)
                     /locus_tag="PC465_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2649772.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKNNNRKFN
                     IKNKIFKGIGILFVLILLGFFIWINKTYEPQKLAKEALVSNSKVEVTVNENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVAASNFARDNKLIEGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNIS"
     gene            complement(2205..4223)
                     /locus_tag="PC465_002487"
     CDS             complement(2205..4223)
                     /locus_tag="PC465_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDF2649773.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYVFSYDLK
                     RAVYVPFGLMYIFMVSIPVGKSEFPMRLSALAVGAVIIMLAQFVMNRNRMKNVGDKEL
                     ISICDELLEKISLLKNTINDDSSIIKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERISLILERYKKDSKEFEDEDIKNILEESSINSKSDVLVVAT
                     KEINYIKMCLENKDTITDKEILGFRDYVIAQDTKNINLKEIYSVLENLYEFLVDYKKV
                     KSRDEKKAERKSKIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIEMYKGIVKNIIDEVNKSIENVADVYYIKNLLLIPSLIEDRLMLINAI
                     YKDKHQEDFLENQKLLISNMYNLYINVNKNKIKDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIVNTKSLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEAA"
     gene            complement(4494..5270)
                     /locus_tag="PC465_002488"
     CDS             complement(4494..5270)
                     /locus_tag="PC465_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDF2649774.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALVLGIIFVGTGLVDKGPVAEFFANTAASKASMPFTALFFRG
                     ILCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSVANMTIYSVSLFSPTI
                     STVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            complement(5327..6298)
                     /gene="asrC"
                     /locus_tag="PC465_002489"
     CDS             complement(5327..6298)
                     /gene="asrC"
                     /locus_tag="PC465_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HDF2649775.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLAIVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEDINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTEFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDKDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKKPRLAEDFLLWVDEDSIIKIILNTYRYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGIKYL"
     gene            complement(6311..7102)
                     /gene="asrB"
                     /locus_tag="PC465_002490"
     CDS             complement(6311..7102)
                     /gene="asrB"
                     /locus_tag="PC465_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HDF2649776.1"
                     /translation="MNPYIPVSAKILDIVKHTDKEWTFRVNCNTKGVLPGKFYEISIP
                     KYGESPISVSGYGEDYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIVGFKSPKDILFADDLKRWSKKLDI
                     LVTVDGAEEGYSGNVGLVTKYIPELDMKDINNTSIVVVGPPMMMKFTVEEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDDTYICLDGPVFDYSYAKNLID"
     gene            complement(7103..8110)
                     /gene="asrA"
                     /locus_tag="PC465_002491"
     CDS             complement(7103..8110)
                     /gene="asrA"
                     /locus_tag="PC465_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HDF2649777.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVLIPFKGTFSDTDVIRYK
                     EVNAFEEMEFAKKANFSPKEVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIRDKVKFALVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDLKDSEFEVFNGEATEFNVDYVTDNLISVDVPENIDSNEMIGNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVISKEE
                     V"
     gene            complement(8501..9190)
                     /locus_tag="PC465_002492"
     CDS             complement(8501..9190)
                     /locus_tag="PC465_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF2649778.1"
                     /translation="MSKLKDYNIDKVIIFNNLSTKTKNQLKEKVKLKRLQKKEILFYE
                     KDSLDSVYILLEGKVSIFKISENGERKVIFILNSGEVINDITLDASKNSTVGCEAFEN
                     SIVAYYSIEEFLELMQNDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     EIELSRYFKNN"
     gene            complement(9253..10101)
                     /locus_tag="PC465_002493"
     CDS             complement(9253..10101)
                     /locus_tag="PC465_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2649779.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            complement(10120..11007)
                     /locus_tag="PC465_002494"
     CDS             complement(10120..11007)
                     /locus_tag="PC465_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDF2649780.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGFIIDKSSLDTEAKEKGGEGIL
                     AKIKDIVKKYIEENEISGICISTAGMVDPVEGKILFALEELIPNYKGMQLKKEVEKEF
                     NIKCEVENDVNCAGLGEMWLGAGRGATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNVNGSSFQELASTSSLIKKVAKIKNLNENDLNGKIIFDLAKNNDEDCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKALKEVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            complement(11065..11868)
                     /locus_tag="PC465_002495"
     CDS             complement(11065..11868)
                     /locus_tag="PC465_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649781.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESIIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNDTIEKF
                     NTGCTTLSKHYNIENKYVIWIQGESDAKYGSDVLYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACSECDILCVGSKIAMQFHDRGLTIDDVHYTQE
                     GLNMLGEDLCKNIYKYHITKEKSVLSDTIDLSEARKYICELEKISKRFV"
     gene            complement(12028..12480)
                     /locus_tag="PC465_002496"
     CDS             complement(12028..12480)
                     /locus_tag="PC465_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HDF2649782.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DIFVNIVEYKTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEKGDFL
                     PLDGKNNGYMELRKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            complement(12610..14112)
                     /locus_tag="PC465_002497"
     CDS             complement(12610..14112)
                     /locus_tag="PC465_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HDF2649783.1"
                     /translation="MVGFTWIDFAILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRVLGALMFIIYQIGRMSIIMYLPSVVLAGLTGIPVNVLIVV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFIGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIAVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKMGAYVGFIVSAILVVYLK
                     YRMPEVTSWAYSLITITTSVVVGTIVSAIEAKVKAKVSLPKAETTVYYEK"
     gene            complement(14145..15011)
                     /locus_tag="PC465_002498"
     CDS             complement(14145..15011)
                     /locus_tag="PC465_002498"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HDF2649784.1"
                     /translation="MKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGS
                     TGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGYDAISA
                     VTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENEKIIGV
                     KFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRARQIFE
                     LTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKEATDEM
                     KSRAKEIYRKYF"
     gene            complement(15096..15767)
                     /locus_tag="PC465_002499"
     CDS             complement(15096..15767)
                     /locus_tag="PC465_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDF2649785.1"
                     /translation="MLDKVKGRLIVSCQALEDEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCVSTTLSGYTPYTKTLEG
                     PDFVLMERLVKDLEIPVIAEGKVNTPQDLKKVFELGVHSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            complement(16040..16531)
                     /locus_tag="PC465_002500"
     CDS             complement(16040..16531)
                     /locus_tag="PC465_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2649786.1"
                     /translation="MEGNTNNKVDDKFSKVKKKFGSGKFKVELYKEKSKLNREIDDIQ
                     EEKAKIFLEMGILTYQKIREDSINDNSFDKFCDELLELDKLIYEKNMEINEMEMAESN
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIICGYCESEIDTEAEFCPCCGRKIII
                     DLE"
     gene            complement(16553..17917)
                     /locus_tag="PC465_002501"
     CDS             complement(16553..17917)
                     /locus_tag="PC465_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2649787.1"
                     /translation="MGEKKINNMNYSHNNYSKNTGEPTRKIKNSHITLKSKEEKICSS
                     CNKENNTKDNYCKFCGNELYEIASLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLVNPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKTVLANSLGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTYKKSYEKENMYLSLFSNSIRTFIL
                     GYVLVLVILLVLTISDSSYLNELDMSSYSNGLNLFTILPQIASYMWAFANGISVTIIN
                     STVSMFTLSSSSLFGDTKLMFYAMGALSMLILLLNGYKLRFKYNTDSIRPIIVFSIYY
                     AFLMGILALFSTFILDSNINFFNTTNYGTTLIMQFKVLQAIVISFVYSFVISLIGYKL
                     NLAD"
     gene            18336..19511
                     /locus_tag="PC465_002502"
     CDS             18336..19511
                     /locus_tag="PC465_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2649788.1"
                     /translation="MNLEKIKKFFGFPLDKKHKDNVEKELCNYLYNTGKIICIIIVIS
                     QIIMMISISAREGGPFVTPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIMLAAAAFSVLKFGESVIVFGGCFLF
                     LNLFLPGIQTIPGNEFSNIVNTFFITSLAIFVSTMLYRNRVFTYYDKLLISQQYEEIS
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCNEAEAKLKSECLRKII
                     ECCNFERDDVPLKCVTVSIGVYTKKIEKTITLNEFISNCDKALYTAKEQGRNCVAFY"
     gene            complement(19684..21081)
                     /gene="asnS"
                     /locus_tag="PC465_002503"
     CDS             complement(19684..21081)
                     /gene="asnS"
                     /locus_tag="PC465_002503"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HDF2649789.1"
                     /translation="MQKEFITVKELYREKEQYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFIRITYTKAVELLIESGHEFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     misc_binding    complement(21158..21391)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(21560..21754)
                     /locus_tag="PC465_002504"
     CDS             complement(21560..21754)
                     /locus_tag="PC465_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3787 domain-containing protein"
                     /protein_id="HDF2649790.1"
                     /translation="MESKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVEEAKDWVDNGSKL"
     gene            complement(22027..23700)
                     /locus_tag="PC465_002505"
     CDS             complement(22027..23700)
                     /locus_tag="PC465_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HDF2649791.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPLDFDET
                     ILNNIIQVAWWEESEPMSSLIEITNNVNNGETITTAAETDYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSELNIAINRND
                     GSLSQDNIGTGTLVSGILVGNGRINSQYRGITTESDLIVVKLKSYTDTYYAGRINYSV
                     SDFLAAITYVTNIARTENKPLIINLTIGVKSSAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYSPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWILRLTSELI
                     INGEYDIYLPNKNLIAPDTRFLDPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVASGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQDNV
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
     gene            complement(23710..27108)
                     /locus_tag="PC465_002506"
     CDS             complement(23710..27108)
                     /locus_tag="PC465_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HDF2649792.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNILLTYPEIEFIEKPFILQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSDGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSIYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELRMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLQNNITEEVEF
                     IVGEGERILNINIWPDFVDDFSVHLVNPSNNQTQAISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWKIVFEPIDIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVITVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIVSFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKGARRLSNQSY
                     PNNSSGFGFLNLSDIDLYTLSNINQDLETEDIGYRSINKSFKDEENSYKFIDGYNMQI
                     HNDLENEIYISKNASRQSGILSGIDIVHTPEFEEELAGLGMSQRFFKISDSLGVLSIN
                     NTDYNSIQRVLQLPSIIRTVSTTKMTLLGEINRGTFGGVVATEEMGVNFFKNNPNINI
                     TGRGTLISIADTGIDYLHPDFIYPDGTSKIVYLWDQTKEGTPPDGFYIGTEYTREDIN
                     RAIAENDPSLSQDEVGQGTMLSGICAGLGNVNSEYAGIAEDSELIIIKLGKIDDFYNS
                     AMLFAASQYAYKKAFELGRPLVINMSLGTSSLAGLTNRSNSEKAFFTRGLCITAGAGN
                     EGNTQTHTSGIIPYVGGSVEVELELNEDEEELSLELWLNRPDKADVIIVSPTGEESKS
                     VGISNYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYII
                     TGRYNLYLPNRELLKSGTRFREVDPFYTINYPAIQDDLITIGAYNTINGSLWQSSSRG
                     PTIEDRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYP
                     NQAYVQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            complement(27276..28472)
                     /locus_tag="PC465_002507"
     CDS             complement(27276..28472)
                     /locus_tag="PC465_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDF2649793.1"
                     /translation="MFIEFFYLLRSRGLNVSLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDAVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKYINTEWILKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFKRKYSKIVWMNPELRDGWDSINYWYQTQRMIQSEFNMFPLTVKGLEKALK
                     NLMVSR"
     gene            complement(28493..29314)
                     /locus_tag="PC465_002508"
     CDS             complement(28493..29314)
                     /locus_tag="PC465_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HDF2649794.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKDLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGMPIEKIEKEVPFAGILLKNNEDIESMQRHL"
BASE COUNT         9496 a         5269 c         2980 g        11644 t
ORIGIN      
        1 gttcacattt tcattattat tgatatatta tatatgaata taccattttg ttttttaata
       61 aaaaaatcat gctacatcaa tagtaagcaa ctattaatgt agcatgattt tttgtatcta
      121 aataatctta gtatttacct atcaatatag attgatatat caaaaactat agtcttctat
      181 attcttctct ttttagcttt tggttactta gatagtaatc aatttcatca attaaacgtt
      241 gtttatcatc aggtaataca ccttttaaat tagcataatt tgatgcatga ttacttctaa
      301 atacaatttt ttcattagca tctatattct ttatcatctc tttaatttct tgtaacacag
      361 ccttatcctc tagtattgta aactctcctg ccttaagtaa atcgtaaagt tcagtattag
      421 gttctaccat taaactaagt acacccacat aatctggtga aattgctcct aacatttttc
      481 ctgtatcaac tgcatgctga tgtgtttttt tagttcctcc aagacctgct attacagtgg
      541 ctgataattt aatcccactt tttttaactt ttctaccaac ttttattaat tgttcactac
      601 taaaaccttt cttaatatct tctaatactt cattgcttcc actttcaagc cctagataaa
      661 tcattttaac accaagtttt cttaattctt taagttcatc atcagatttt ttctctatag
      721 atttaggaga gccgtacata gtaattcttt cacactctgg aaaaacttct tttatatata
      781 aaataatatc tcttaatttc tccattggta ttatcaatgc atctccatct gctaagaata
      841 ttctttctac atgcttataa tatcttctaa atatatcaat ttcatttttt attacttcta
      901 gtggctttat tttaaatttt ttagatttgt acatactaca aaacgtacat ttgttatgag
      961 aacatcctag tgtgacttgt attataagac tataagcctc acttggtggt ctgtaaagtg
     1021 gcatatcgta ttccatatta aaatccccct tgtaataaaa tattcattct attatattat
     1081 taatatttac tttaaataat aacttataaa attatatttt ttaaatttta gtttaagata
     1141 tattctttaa aaatttaatg atactattgg cagtaatatt aagttgtttt tcttgactta
     1201 taatagcatc attatctccc ttttgttttc cataatctcc aaattgtgca tgatttcctc
     1261 cttcaatctc aacataagtt gtatcatcag gaagtttttg ttttgattct acaagacttt
     1321 taaaattgac tactccatct ttgctccccc atatagatat aacttttttt cctaattctt
     1381 tcaactcatc acccattgga taagaagcta aaaatacaac gccttcaatt aatttattat
     1441 cacgtgcaaa atttgatgct gcaactcctc ctaatgaatg acctcctatt acccaatgtt
     1501 ctatgttgtt gtaagaatcc ataactttct gtgccttatt agttccaagt atagctagat
     1561 taagtggcat ctttacgatt acaacctcat atccactttc tgctattttt cttgcaagtg
     1621 gagcataaga ttctatttct actttagctc ctggatacaa aattaaacct ttagaaactt
     1681 ttcttccttt tggtgtaaat gaaatgtttt catttacagt tacttcaact ttactattgc
     1741 tgactagagc ttcttttgcc agcttttgag gttcataggt tttatttatc catatgaaaa
     1801 agccaagcaa aatcaataca aatagtatac ctattccctt aaatatctta ttctttatgt
     1861 taaattttct attattattt ttatcatctt tgttctcaac ctcatcataa agtaaaggtc
     1921 tctcaagttc catagttata ctaaatgtat catatttctt attacgcttt acctttacat
     1981 ctttactcat aaatctaacc cccataatat ttgaatacta ttatagttta tcctaagtaa
     2041 attgtttttt caaccaatga aaaaaatcaa tattttaact attttcatat aaaattcata
     2101 aatatatgtt ttttgttttt tatatattat tttcttttag tattttataa aacaaatagc
     2161 catatacttt attttaaata tatggctatt ctataattta atatctaagc tgcttctttt
     2221 attgaaactt tagttatatt acttattcta tacatttctt tgacaccatt tagagtttgc
     2281 agtaagttta gacatattat cttgtcacct agacttttag tatttacaat actctctaaa
     2341 attacacttc ttccttcatc atacttatct acattgtaat ttgaaatata attagtatct
     2401 ctcaatattt tttcaacatc ttcatctttt attttatttt tattaacatt tatatataga
     2461 ttatacatat tacttattag taatttctga ttttctaaaa aatcctcttg atgtttatct
     2521 ttatatatag catttatcaa cataagtcta tcttcaataa gtgatggtat caataataaa
     2581 ttttttatat agtaaacatc agctacattt tctatagact tattgacttc atcaattata
     2641 tttttaacta ttcctttata catttctata acatgttgat agcctgtttt agcatcatat
     2701 ggtaatataa acttatttac tattaatgca ataattgctc ctaatgctac atatgaaatc
     2761 ctgcttatgg ttaaaacatt tgggtctccc ataactactg ctgaaccaag agctgaaaca
     2821 gttacacata ccattaattt tctataatca accacataag agtttatata ccctgctaaa
     2881 agaactatta acgaccttaa tgtactatct tttattattg aaaataatac aataaatatt
     2941 acagctccta taaatgtacc ttctattctt tttctagacc tttgtataca attttctgcg
     3001 taaggttgtg ttaatgaaaa gacagttaac attatccatc ttccatctct taaatggaaa
     3061 taatccataa taaaacccgc tacagctgta gctaaagcaa tctttactgc ataagaaaat
     3121 cttatagaat ttaaattaaa gtttttctta tatattgata gtcgtttaaa ttcatgaggt
     3181 atctttgatt ttctttcagc tttcttttcg tctcttgatt ttactttttt ataatctact
     3241 aaaaactcat ataaattttc taaaacacta taaatttctt ttaaatttat atttttagta
     3301 tcctgagcaa taacataatc tctaaatcct aatatctctt tatcagttat ggtatcttta
     3361 ttttctaaac acatcttaat atagtttatt tctttcgttg ctacaactaa aacatctgat
     3421 ttactattta tgctactttc ttctaaaata ttttttatat cttcatcttc aaattcttta
     3481 ctatcctttt tgtatctttc caggattaaa cttattcttt ctaatgaaaa taaaatattc
     3541 attatgtcta tacctctaat actgatataa aagtcatctt ttctattatc aaaaataacc
     3601 attttcaaat ttttagatat agaatttatt ctataattac agctatctat ttttctcata
     3661 ctagatttaa ttatagaact atcatcatta atagtatttt ttaaaagact aattttttct
     3721 aataattcat cacatataga tatcagttct ttatctccga catttttcat cctatttcta
     3781 ttcataacaa attgagcaag cattattata actgctccaa cagctaaagc cgacaatctc
     3841 ataggaaatt cactttttcc tacaggtata cttaccataa atatatacat tagaccaaaa
     3901 ggtacatata ctgctctttt taagtcataa ctaaatacat accctattat aaataatgct
     3961 ataaaattta ataaaactcc taaatacata ttttgtactg caaaaaatga tagtattcct
     4021 aagattatat ttattgctaa atacttcagt aaatttttaa ttggagaaat agttaaatct
     4081 ctttccaaga gtgttagcat agctgttact atacctacac ctataagtgt atttttactt
     4141 ccaaataaat atataaatat agaaataaat gctattataa aaataaacaa ctttgttttt
     4201 gatattacta gtttctttgt catcatatcc cccctaaaaa tttcaacaag accaatttta
     4261 tcatatttgt tatcttattc aaaatgcgct tttttacggt aggactttaa ctttttttat
     4321 atttagaact atataattca tatgtaaacg tattttttat atatataacc gatatatttt
     4381 cgtatgctcc catatttttt ttgtttcaaa tattttttca aaaatataaa aataactctc
     4441 tcaataatac taaaaatgca tttatcaaga gagttataat ttatacaata aatttaatta
     4501 agcttttctt tacctaatat ataagttcca agacccataa ataaagctcc tccaacaata
     4561 tttccaagtg ttacagctac taaattataa atagctcctc caatagtaac tgtacttatt
     4621 gttggtgaaa ataatgaaac actataaatt gtcatatttg ctacactatg ctcaaagcct
     4681 gatgttataa aagcaaataa acataagaat atcataatta tttttgcagt atcactatta
     4741 gttctaaacg aacacaacac tgatacacat actagaatat tacataaaat ccctctaaag
     4801 aaaagagctg taaatggcat ggatgcttta ctagctgctg tatttgcaaa aaattcagct
     4861 acaggtcctt tgtctactag accagttcct acaaatataa tgcctaaaac caaagctccg
     4921 attaaattac ctacccaact gtatgcccat attttagaag tatcttttat acttacacct
     4981 ttatttaaca taccagcaga cataaccata ttgtttccag taaataactc tgttcccgtc
     5041 attataacca aacttagtgc tattgcaaat gataacccca ttactatctt agtcataggt
     5101 gaacctgcat cagtcaaaag tcctccaata gtaaatatca aaagtatacc tatacctaca
     5161 taaagtcctg caaacgcaga agataccaaa tattttactt tacttgtgtt taataaattt
     5221 atcttattta tagctgcatt agttaattta tccaaagttt ctttatgcat aattccctct
     5281 tccttctatt aaattttaat ttattcaaat atatgtttta ctcaatttat agatatttaa
     5341 ttccactcca gtatatgttt tcgtacattt tagttatttc tggaagctct acaccttcaa
     5401 gtgcccattt tttaaattcc ataaatcctg ttctatcaat tatatatcct atatgttctt
     5461 ttcctcctgg tgcatcttta tctatatact tttctacata tctataagta ttaagtatta
     5521 tctttattat gctgtcctca tctacccata aaagaaaatc ttctgctagt ctaggttttt
     5581 tctttcctgt tctacccatt atagctaatc tatagtattt tttctcatct ctagtccatg
     5641 catttgttgg gcaatttagt acacactctc cacagcctat acacttatct ttatctctta
     5701 ccaccttatt attttctgtt tttaatgctc caacagatat cttagaacat ttttttacac
     5761 atgctccaca atttacacat ctatcctttt catatattgg taaagccata ccaataattc
     5821 caaagtcatt cattctagct tttatacaat catttggaca accagttaaa gccactttaa
     5881 aatgtaaatc atttggaaat atagcttttt ctattctttt agcaaattca gttgtattat
     5941 attgagcctt tggacagact ttatttccta tacaagctgc tatatttctt gtacctgccg
     6001 ctggataacc tgcgtttttc tcactttgat ttatattcat tttttcaata acaggttgta
     6061 taattttatt tatatcttcc atatcttcca tatttattcc taatatttca aacccctgtc
     6121 ttgtagttat gtgcacctgt ccattgccgt actcacttgc aattttagaa actatagcta
     6181 aactttcagg gtcaataaga ccaccaggta ctctaactct taaagaagtc tcatattttg
     6241 tttttgtaat tctataagca tttttcatta cttttttggt atttaaatct cttatcacaa
     6301 acttcacccc ctaatcaata agatttttag catatgaata atcaaatact ggtccatcta
     6361 aacatatgta agtatcatcc attttacaat gtccacattt acctattcca caacacattt
     6421 ttctttcata agaaacccaa atgttctttt catctaaatc tctttttaaa aattcttcta
     6481 ctgtaaattt catcatcatt ggaggtccaa ctacaactat agaagtattg tttatatctt
     6541 tcatatccaa ttctggtatg tattttgtta ctaatcctac attaccacta tatccttcct
     6601 ctgctccatc tacagtaact aaaatatcaa gttttttact ccatctcttt aaatcatctg
     6661 caaataaaat atcttttggt gatttaaatc ctactattaa tttaaacttt tcgcattttt
     6721 ctttattatt ataaaaatat tcaactattc ctcttacagg ggctaatgca cttcctcctg
     6781 ccactactac aatttctctt ccttcataaa gggatacatc aaatccattt ccataaggac
     6841 ctcttataaa aaaagaatct ccttctttat aattaaacaa ctcgctagtt acttttccta
     6901 catttcttat tgtaaagtca atataatcct ctccatatcc tgatactgat attggacttt
     6961 caccgtattt aggtatagat atctcataaa actttccagg caatacacct tttgtattgc
     7021 agtttactct aaaagtccat tctttatcag tatgtttaac tatatctagt atttttgcac
     7081 ttactggtat atatgggttc atttatactt cctccttact aattactaaa tcatttattt
     7141 tttctataca ctttgaaaat gatatgtatt gcggacaggc atcatcacat cttccacagc
     7201 caacacacat atgatatccg aatctttttt taaaatcatg tattttatgc atagttttaa
     7261 atctcattct ttcgccttgt ttttttctaa aagaatttcc acctgctata tctgtatatc
     7321 catctacttg acaagaagcc caaacccttc ttctctcacc tacattttcg ttttccttat
     7381 agaaaatatc ctgcattgta aaacatgaac atgttggaca tacaaaatta catctaccac
     7441 atcctataca tcttgtatca tattcatccc atattgaatt tcctatcatt tcatttgaat
     7501 caatattctc tggcacatct acagatatta aattatcagt tacataatca acattaaatt
     7561 cagttgcttc tccattaaat acttcaaatt cactatcctt taaatctaag tacagtgtat
     7621 ctccttctat atttaatcca attgaataat tatcagtttt gttagaatcc atgctcacac
     7681 aaaaacagtt tctaaaactt tccttacacc ctacaagtgc aaactttact ttatctctga
     7741 tatttttata aaaataatct ttttcttcac cattatttag atatatttca tcaagtcttt
     7801 ttataccatt tatgtcacaa gctcttaaga aaattaaaat tttcttgttg tctaaatcgc
     7861 tttccttaaa ctctttttca gtaaaataaa acaatacttg atttatggga agtacaactt
     7921 cttttggtga aaagtttgct ttcttagcaa attccatttc ttcaaaagcg tttacctcct
     7981 tgtatcttat aacatcagta tctgaaaaag tacctttaaa tgggattaaa actggtgcaa
     8041 atatcttgta gtcttttttt agataattca gaccttcatt gaacttagat gaatctaatt
     8101 ttagtttcat ttttatcacc tttcttatat tttagtttta cttacttgct atcttgttta
     8161 aatcttaaca ctttattttc tatgcttccg tgataattat cacagtttca aaaataataa
     8221 aaaaaatatt aatggagttt attaagttct gttaatattt ttttattatc tacattattc
     8281 aatttcaaat ctaatcactt aaatacaatc attaagtaca ataaaactac tatctactca
     8341 attttttgaa taaaaaagaa tcttatttgt ttttttatac aattcaatag ggtaaaataa
     8401 aaattaataa attagacaat aaaaaagaat ctataaatag attctcttaa taatattttt
     8461 atttaattaa aattctaata atactcttac ttaatcataa ttaattattt ttaaaatacc
     8521 ttgataattc aatttcttta acataaaaac ctttattgtc aattttaata agttcttctt
     8581 tttgcaatac ctttatcatt ctggaaacag tctccctttt acagccaagc atatcagcta
     8641 aatatgtaac tgtaatattt acatttagta aagtccattc tccacagcaa actccaaatt
     8701 ctctacttaa cctatataat tttgctgcaa gttttttatc tacttttatg gatatagaat
     8761 ttttcaactg tctatataaa cgtcttattc ttctttccat ataagaaata atatcctttg
     8821 taagttgaaa atcattttgc ataagttcta aaaattcttc aatactataa taagctacaa
     8881 ttgaattttc aaatgcttca cagccaacag tagagttttt agaagcgtca agtgtaatat
     8941 catttatgac ttccccacta tttaatatga aaattacttt tctctctcca ttttcactta
     9001 tcttaaaaat agataccttt ccttctaaaa gtatataaac actgtctaag ctatcttttt
     9061 cataaaataa aatttctttt ttttgtaatc tttttagttt aactttttct ttaagttgat
     9121 tcttcgtttt agtacttaaa ttattaaaaa ttattacttt atcaatatta taatctttta
     9181 atttagacat gtaatatctc tccattccta aatttttaag agagctctat aaaacattac
     9241 aaatttctta ttttattcat ttttaaacaa ttttatagca tttgtagttt taattttcct
     9301 ttcaatagct tcattagaaa gttcttttac tacctgtgta tatactaaat caataatgaa
     9361 aaattgtgct aatttagaag atattgaacc ggtttccagt actgtttctc ccgatacata
     9421 agataagtgt acatctgaaa tatcctttaa ttcagaattt ttattttcag taattgatat
     9481 aattttagca ttattggctc ttgcaagctt tacagttttt ataatctctt ctgtttcacc
     9541 agaatgtgaa attgcaatta ttaaatctcc ttcttccatt atggaagaca tcattatcat
     9601 tgtatgacta ctgtcaaaac ttacacaatt aagacctatt ctcataaatt tatagtttga
     9661 atcctgtgct attataccag aatatccaat acctatgaag taaactttct ttgcatttat
     9721 tataagcctt gcgcagtcat gtacatcctt actattgatt atctctactg tgttctctaa
     9781 agtggttaca tttgaactta aaagtttttt tgctgtatcc aaagctggct catcattttg
     9841 tatattttta tttataatat tttttttatt gatagttgat atttcttgtg ctaaagtaac
     9901 tttaaaatcc tgtaatccat taaaattcat tttttttaca aacctagtta tagttgcttc
     9961 accaatattg ctctctttag ctatttgtga tattggttta taaaatacat catctatatt
    10021 ttcttttata taagctatta ataatttatc tgattttgtg actttaaaag ttggtgattc
    10081 caattgttct aaaatactca ttaaaaaccc ttctattctt tatattttgt ttaaaaaatt
    10141 atataatgct ccaagcattc ctgcatcatt ttgtctcttt gcaaattcta tattagtgtt
    10201 tttgtaaact ctctctataa gaacctcctt taatgctttg tctatttttg gttttaggaa
    10261 cttttcttgt gccataatcc caccacctaa aattaccact tctggattta ttacataaca
    10321 tatatttgcg attccaactg ctaatgattt tatcatatta tcgagttctt ttaaacaatc
    10381 ttcatcatta ttctttgcta aatcaaaaat tatttttcca tttaagtcat tttcattcaa
    10441 attttttatt tttgctactt ttttaattag actgctagta gatgccaatt cttgaaaaga
    10501 acttccattt acattcatat atcctacttc accagcacta ttactaaacc catttatcag
    10561 tttattattt attataatac atccaccaat tccagtacct attgttaaac atatagaaga
    10621 tgttgcacct ctacctgctc caagccacat ttcaccaagt ccagcacaat taacatcatt
    10681 ttcaacttca cattttatat taaactcttt ttctacttct ttttttaatt gcatgccctt
    10741 atagtttgga attaattctt ctaatgcaaa tagtatttta ccttcaactg ggtcaaccat
    10801 acctgcagtt gatatacata taccacttat ttcattttcc tctatatatt tttttactat
    10861 atcttttatt ttggctaata ttccttctcc acctttttcc tttgcttcag tatcaagact
    10921 tgatttatca attataaatc catcttctct aataaaacca tattttattg aagtaccccc
    10981 aacatctata caaacgtaat ttttcataac atatctccat acaaattatt tttataaatt
    11041 aacaactcta tttaaaattt tatattacac aaatctttta cttatctttt ccaattcaca
    11101 gatatatttc cttgcttctg ataagtctat agtatcactt aatacacttt tttctttggt
    11161 tatatgatac ttataaatat ttttacataa gtcctctcct aacatattaa gaccttcttg
    11221 agtgtaatga acatcatcaa tagttaatcc tctgtcatga aactgcatag caattttgct
    11281 tcctacacat aatatatcac attcactaca agccgactcc tgtgctgctg caattcgtct
    11341 tgttctaata aaatattcat cttctccaag ccaataacca gttaaactta caaacatttt
    11401 atcaatcata cattcttctt taagcctata cgcaattttt tttagacttt ctttatagta
    11461 caatacatca ctaccatatt ttgcatcact ttcaccttga atccaaataa cgtatttatt
    11521 ttctatatta taatgtttac ttaaggtagt acagcctgta ttaaattttt ctatagtgtc
    11581 atttagaaac cagttattat catgattcca gttttttatt cttgaaccat cttttgcatt
    11641 gtgaataaaa caaactttat ttccagtaag cttattccat tcatttgaaa atgcaggtgc
    11701 tatagtacca tcaccttctg aagtctctag ctcacatctc atatttataa tttcatcagt
    11761 actcaaatat tcaaaacaat tttcatttgg aatgatgctc tcttttggat ttcccaatcc
    11821 tctagcattg ctttgtccta ttaataagaa tacatctata ttttccataa gttaactcct
    11881 ttacaaaatt ttaagctttt aattattttc aattttctca taaaaaacta aggctgaaaa
    11941 tagtaatcta actaaaattt acgaagtctc actaatcgct gaaagttaaa tcactatttt
    12001 cagccctagt ggttatataa attatcatta tctaaccaaa accttaaaaa tagctttttt
    12061 gatattttct ttttctaaaa cttttattcc tgtcatatga gcatcttccg gataacaaac
    12121 taaaaaatca ccttttctaa gttccatgta tccattattt ttaccatcaa gaggcaagaa
    12181 atcgcccttt tcttcatata ttttttgttc taaattttct ataaaattta tatctattcg
    12241 ttcacatcca tcaagcatca aatgaacatc tatatacttc ttatgagctt cccagaatct
    12301 atcttctttt tcacaagttt tatactctac aatattcaca aaaatatcat caccatctat
    12361 tgtataagta cctttttcat aatctattaa tgaattatct ttagcatatt caaaacatct
    12421 aagtaaatct tcatgcaatg ttgaatatgt cttactatga tttatatttc caaatatcat
    12481 aagcactatc tccctatata attataaagt ctatttttat acttttatat acaaagtata
    12541 ttatacaatc ttatagagta actaaattat ttatctaatc actctataag acaatttatc
    12601 atttaaatat tatttttcat aataaacagt agtctcagct tttggtaaag atacttttgc
    12661 tttaacttta gcttctattg cactaactat tgtacctacc actacagaag tcgtgattgt
    12721 tattagagaa tatgcccaag aagttacttc tggcatacgg tattttaaat aaacaactaa
    12781 aattgctgat actatgaatc caacatatgc tcccatttta gtcgcttttt tacaaaatgc
    12841 accaagtaca aatattcctg ctaaaacacc tagtactagc cccataaaac tattaaacca
    12901 ttcatatgct gactttattt ctccatttgc taatactatt gcaacagcta tagaaagtat
    12961 acctacacct aatgatatat attgtgctat cttagtttgc ttttccatac ttatatcttt
    13021 tgttatgata gtttgtatat ctaaagtcca acttgtagca actgaattaa gccctgtcga
    13081 taaagttgat tgagaagctg catatatcgc tgcaagtagt attcctgtta tacccactgg
    13141 taattcataa gctatatatg atgcaaatac ttggtcttgt tgaactgttt gagctaaatc
    13201 tgggttttga gtatagtata taaataaaca agttccaatt agataaaata ctgttgcaag
    13261 tcccattgat aaaacaccat ttccatatgt cattttatta agttgcttta tatcagttgt
    13321 tgtagtaaac ctttgaacta tatcttgact cgatacatat gatgaaaaag tattaagacc
    13381 agctccaata aatattataa atgcacttgt agatagtata tttttatcaa acataacttc
    13441 attacttgct aagaacttgt gtccagttgt aagagtatcc attactgttc caaaaccacc
    13501 atttatactt gctattaaat agaacaatgt ccctgtaaca cctactatta ataccatacc
    13561 ttgtataaaa tcggtccaca agacagcctt taatccacct gtatatgaat aaattattgc
    13621 tattacaccc ataactacta tcaatacatt tacaggtatt cctgtaagac cagctagaac
    13681 cactgatgga agatacatta tgatagacat acgtcctatt tgatatatta taaacatcaa
    13741 agctccaagt actctaagac ctttactttc gtatctcatt tctaagtatt catatgctgt
    13801 atctatttct aacctactat atagaggtaa gaaaaatttt attgtcaaag gtattgctat
    13861 aaacatacct aattgtgcaa accacaaaat ccaagtacca ccataagaat ttcctgctaa
    13921 tgataaaaat gatattggac ttaataatgt ggcaaatatt gatactgatg taacccacca
    13981 cggaatagtt ccatcacctt tgaagaactc ttttcccttc atttcctttt ttgaaaataa
    14041 caatcctgca aataaaactg ccaataagta aaccactagt attgcaaaat ctatccaagt
    14101 aaatcctacc atttgactaa tcctcccata ctaaaagtat tttattaaaa atactttctg
    14161 tatatttctt ttgctcttga tttcatttca tcagttgctt ctttcatagg ttgtctacag
    14221 tatccagcct caacaccttg ttcttcaagt agtaatttaa ttgtttgata taagccattt
    14281 cctaatatat ctgttattaa atcattagtc acatgttgta cttcaagtgc ttctgatatt
    14341 ttttcattct tagttaattc gaatatttgt ctagctctga caccgtttac attgaatgta
    14401 gaaccaattg ccccatctac acctaaaact gtagctggta acatcatttc atcaaatcct
    14461 gcaaatatta atttatttgg gaatgttttt ctcattctct ctaataagta gaaatctgct
    14521 gctgtaaact taacacctat tattttttca ttttcaaata attctccaaa ctggtctaaa
    14581 ctcatatcaa caccagttaa aaatggtata gagtatatta ttaatctatt atctacagaa
    14641 tttattattg tattataata gtgttttatt tcttcaaaat caaatttata gtaaaaaggt
    14701 gtaacagcac ttattgcatc atatcctaaa tcagttgtaa atttagcaag ttctacagct
    14761 tcttttaaat taactgaacc aacttgagct attaatttta tttcttcttt cacttcatct
    14821 ttagctattt caaatattct tttcttttca tcagttgaaa gcatgaagtt ttcccctgta
    14881 cttcctccta cataaagacc atctacttta caaacatcta tattgtgtct aattatttgt
    14941 cttaaccctt tttcatttat atttccttcc ttatcaaatg aaactaataa tgctgaataa
    15001 attcccttca tatctgttgt tctcatatct ttacctccaa ttttaatttt caaatatagt
    15061 taaatataat aattttttaa tttataaatt aatttttaat taatttcaat tgctttaaca
    15121 aatttttctg ttattaattg tggtcttgtt attgctgaac ctactactga tgaatgaaca
    15181 cccaactcaa agaccttttt taaatcttga ggagtattta cctttccttc agctattaca
    15241 ggtatttcta aatctttaac taatctttcc attaatacaa aatctggacc ttctaatgtt
    15301 ttagtatatg gagtatatcc agatagtgta gttgaaacgc aatctacacc gtactcttgt
    15361 gctttgatag cctcatcata atttgaaata tctgccatta ctagaacacc gttttctttt
    15421 atatacttta taagttcttt taagtcttca ttatttggtc taactctatt ggtagcatct
    15481 aatgctatca tttcacaccc tgttgttaaa agttcatcaa cttctttttt agttggcgtt
    15541 atatatatat ctgaatcttc atagtttctc tttataatac ctataacagg aagtccagta
    15601 acttttttta tttcaataat atcttcaact ccttgagctc taattccaac agctccacct
    15661 tccatagcag ccttagccat tctccccatt ataaaaggac tatgaagagg ttcatcttct
    15721 aaagcttggc atgatactat taatcttccc tttaccttat ctagcatttt ttaaattacc
    15781 tcgtttctga aatttatttt cttgatttat gtattaataa taacatgaaa actttttctt
    15841 tgcaatattt tttcatattt ttttcttgca tctatatttt tactgattta ttttatatat
    15901 tagcttgttt tttacattta aaagaaattt tatttcattt ttttggtgtt tattttcatt
    15961 ttatataact actgttataa gtccatttaa ataatttcaa taaaaaaacc catgtatact
    16021 atacataggt ttcccaatat tattctaaat ctattataat ttttcttcca cagcatggac
    16081 aaaattcagc ctctgtatct atctcacttt cacaataacc acaaattata aaatcatcac
    16141 attcattttc caattcaaat tttttaccac attcagcaca atatttatca tttacatttc
    16201 caacataacc acactcacaa gttacattac tttctgccat ttccatttca ttaatttcca
    16261 tatttttttc ataaattaac ttatcaagtt ctagtaactc atcacagaat ttatcaaaac
    16321 tattatcatt aatagaatct tctctaattt tttgatatgt cagtattccc atttccaaga
    16381 atatctttgc tttctcttct tgaatatcat caatctctct atttaatttt gatttttctt
    16441 tatataattc aactttaaat tttccactac caaacttttt cttaacctta gaaaatttat
    16501 catctacttt attattagta tttccttcca cagaaattcc ctccaatcat atttaatcag
    16561 ctaaatttag cttatatcct attaaagata tcacaaaact atatacaaat gaaatcacaa
    16621 tagcttgtaa gactttaaat tgcattatta aagttgttcc ataattagtt gtattaaaga
    16681 aattaatatt actatctagt ataaatgtac taaataaagc caatattccc atcaaaaatg
    16741 cataatatat actaaatact attataggtc ttatactatc tgtattatac ttaaatctta
    16801 gcttgtatcc atttaataat aatattaaca tagacaatgc tcccattgca taaaacatta
    16861 atttagtatc tccaaataaa gatgaagaac ttaaagtaaa cattgatact gttgagttta
    16921 ttatggttac tgaaattcca tttgcaaaag cccacatata actagctatt tgtgggagta
    16981 tagtaaataa atttaatcca tttgaataac tactcatatc tagttcattt aagtaactac
    17041 tatcagatat agttagtacc aatagtatta ctaatactaa aacataacct aatatgaatg
    17101 ttcttataga atttgaaaaa agagataaat acatattttc tttttcataa ctttttttat
    17161 aagtagttat gtatgtacat ataaacccta atacgaatcc atttaaaaga acactaaaaa
    17221 attcataact atattctaat gcatatccat attctaacat actatgtgaa ctagttttta
    17281 cattagtaaa aatagataaa atagctaaaa ctaatccata aaaaattcca actcctagag
    17341 aatttgctaa tacagttttt gaatctctac atctttttct cataaaaatt aggtttgata
    17401 ttaataatac caaaataggg attataagta atatcaacaa acctatattg gcatttataa
    17461 acccagaacc catcatggta gacatagata cactaatttg acccaagttg agagctagga
    17521 ttatatgtgc tggatttact aaataactaa tatcattaaa ttgaatagtt ataatagctt
    17581 taaatatcaa tgcaataata aacaatataa atatggttgt aaatgttgtt aaaaatacac
    17641 ctcttttatt tgcatgatat gaaagctctt ttattttaga tttcaagtct agttttgttt
    17701 caagtggtct taatgatgct atttcataaa gttcatttcc acaaaattta cagtaattat
    17761 ccttagtatt attttcttta ttgcaactag aacaaatttt ttcttcttta cttttaagag
    17821 tgatatggct attttttatt tttctagttg gttcacctgt atttttggaa taattattat
    17881 gtgaataatt catattattt attttctttt cacccatttt ttccctccaa gttttactat
    17941 tgtaaattat caaatataac tatatcatat aaaacttaat tataccttaa ttggatatat
    18001 ttatctattt tatttgttta ttgctgttgt tttttaacag gtcttgatat ttaaatagtt
    18061 tgttaatgcg aactttatta tttatatttt attatgctta atttaaattt attctattct
    18121 ttattttcag tagtaaacta tctgtaaatc ttaattataa taaagtatta atcaataaag
    18181 ttactcgaca ttatctaata aattttatct atcacaattt tagattgtta cacacaatat
    18241 attttgatat aattaaatca taaacgaagt attccaaata tctaatgata gaaaggaata
    18301 cttattttta tgctttattt ttaatggagg cttatatgaa cttagaaaaa ataaaaaaat
    18361 tttttggatt tcctctagac aaaaaacaca aagacaatgt tgagaaagaa ctctgcaatt
    18421 atctttataa tacgggtaaa atcatttgca taataatagt aatatctcaa ataattatga
    18481 tgatatcaat ctcagctaga gaaggaggcc cttttgtcac accaagacgc caatggtatt
    18541 tttatatgta tgtaacacta ttttgtgtat cttctgtctt tatgtttgta ttttcttacc
    18601 tttggaataa aaaaaaggat tgctgtacgt tttatataaa tttatggata atttatgtga
    18661 cttttttctg cctatggggt tgtgtaatta ctctacttga ccagttaggt ggaaatgacc
    18721 taagtgtatt tagttatatt atgttagcag ctgcagcttt ctcagtatta aaatttggag
    18781 aatcagtaat agtttttgga ggatgctttt tgtttcttaa tttattctta cctgggattc
    18841 aaactatacc aggcaatgag tttagtaata ttgtcaacac attttttata acatcccttg
    18901 ccatttttgt ttctacaatg ctatatagaa atcgtgtatt tacttactat gataaacttt
    18961 taattagtca acaatatgaa gaaatatctc atataaataa tttacttaac gacaaagtta
    19021 tgacagatga ccttactaaa atgaacaacc gtaggtacct tgaagatatt ctacaaaaaa
    19081 aattaatcag ccatgcaaat caagaaccta taactggaat gatgatagat atagattatt
    19141 ttaaacaatt taatgataat tatggacatc aaaagggaga ctattgtcta caaaatattg
    19201 ccaaagtaat tttagatttt acaagttctg aaaatgaaca tgctatacga tatggtggtg
    19261 aggaattttt tatatgtatt tttaactgta atgaggcaga ggctaaactt aaatcagaat
    19321 gtttacgaaa aattatagag tgctgcaatt ttgagcgtga tgatgttcct ttaaaatgtg
    19381 taactgttag tattggagtt tatacaaaga aaattgaaaa gacaataaca ttaaatgagt
    19441 ttataagtaa ttgtgataag gctctatata ctgcaaaaga acaaggacgt aattgtgttg
    19501 cattttatta aaaagttaca tactattaca taaacctata agtattatat cgcaaaataa
    19561 aagtaatcaa attatatatt tatagtacaa taaaaataac ttgcatatct ctaaaataga
    19621 taaatatgca agtcatttta gtgtttatac ttaaagttat ataggtttta ttatatataa
    19681 ttattaaaat tcagcatttt taggagttct tgggaaaggt ataacgtctc ttatgttaga
    19741 catacctgtc atatacataa ttattctttc aaatccaaga ccaaatccag agtgagtagc
    19801 agtaccaaac tttctaagtt ctaaatacca ccaataatct tcttctctta atcccatttc
    19861 attaattcta tctaacaata catcttctct ttcttctctt tgagaacctc ctacgatttc
    19921 tccaactcca ggaactagta aatccattgc tctaacagtt ttaccatctt cattcattct
    19981 catatagaaa gcttttatat cttttggata atctgtaaca aacactggac aattatatat
    20041 ttgctccgtt atatatcttt catgctcagt ttgaaggtca catccccact caacaggata
    20101 ttcaaattca tgaccagatt caattaataa ttccactgct ttagtatacg ttattctaat
    20161 aaactcagag tttactatct tatttaatct ttctaacaat cctttatcta taaaactatt
    20221 aaaaaattcc atttcttcag gagcattttc taatacatag cttataacat attttatcat
    20281 atcttctgca agttccatgt tatcttcaag gtctgcaaaa actatttctg gctctatcat
    20341 ccaaaattct gaagcatgtc ttcctgtata agagttttca gctctaaatg taggtccaaa
    20401 agtataaacg tttctaaaag aaagtgccat tatctcggca tttaattgac cactaactgt
    20461 taaattagcc tcttttccaa agaaatcttg agtatagtct attttgccat cttcagtttt
    20521 tggaatatca tttaaatcca tagttgttat tctaaacatc tctcctgcac cttcacagtc
    20581 actacctgtt atgattggag aatgtgcata tacaaagttt ctttcttgga agaatttgtg
    20641 tattgcatag gcagctattg atcttactct aaatacagct gaaaaagtat tacttcttgg
    20701 tcttaaatgt gctatcgttc ttaaatattc aagcgtatgt ctcttctttt gtagtggata
    20761 cgaactatct gattcccctt ctacaactat gctttttgca tgtatttcga ctggttgttt
    20821 agccccttct gtagatacta actctccctc tacaagtata gatgagctta ttgctaattt
    20881 tcctacctct ttaaaatttt ctactttctc atcaaatact atctgcatat ttttaaagaa
    20941 gcttccatca tttagctcta taaatccaaa atttttagat actctagatg ttcttatcca
    21001 tccagctact tttacagtct tccctatgta ctgttctttt tctctgtaca attcttttac
    21061 tgttataaat tccttttgca ttttaaatcc tcctagtata attgttatta atttctttta
    21121 aatataattt caataaaaaa agcccttcat ccctatataa agggacgaaa gactattact
    21181 ctcgcggtac caccctagtt gtcataatga cctcttagtt aagcaatgct taaagcctat
    21241 aacggtgcct tccgtctaag tctacttact aaataagctt tcgattagaa actccaagat
    21301 gttcttcaat ataaacctcg tattgagctt tcaccatcct caactcgcta gaactacatt
    21361 ttatatctac tcttctcttc acagtattta tcttttatta tttctgctaa ttaacaaaat
    21421 tataccaatt tataaatttt tagtcaataa atttatataa ttgatactga ttgttattta
    21481 aaatataata attctacctt acataatgat aataaatact tatcttcatt acttctttat
    21541 tacttcaatt tccaaaattt tataatttac ttccattgtc aacccagtct tttgcttctt
    21601 cgacaccctt aattgaaggt attgaaactt tactatgagg ttttaatttt tcaacatcag
    21661 cccatgctgc tgtcgactca tttccaacta aaagtgaact tttaagtctt ttattatctt
    21721 taccttttaa tgctcttgcc tttttacttt ccaaaactat cacctctatt atttattttg
    21781 taatagtttt agcaatttta caaataaaat tcataagtct aaattataat gatttttaaa
    21841 ttaacatcat atcttttcaa tacttaattt atacctattt atatacaaaa tatttacttt
    21901 gtgtattcaa aatataaaac tattttttaa ttttcatatt tattttttat gctatttttc
    21961 tactctatct aaagtatttg atacaattaa actaataatc aattataatt ttacataggt
    22021 tcttatctat agagtatttg ctatctgttg aatcgtattt tttaaattta aaatcccata
    22081 tccctgcgat acatttggat atgtatatat ctcaagtttt gtagcaccca atattaaata
    22141 tgtttttaaa acttgtgtaa acaatgataa tctcggtaca ttatcctgtt tttctaagta
    22201 ttccatcaat aaggctaaaa cacctgtgac tatagaactg ctcactcctg ttcctgttcc
    22261 tgtattatat gttccatttt tatatgtgga tattatatct acacctgaag ctactatatc
    22321 tggcttaatt cctcttcctc taattggtcc tttcgaagaa ccaatccaca tactatcagt
    22381 cttattgtta aatgtaccaa ctgtaattac atcatcacta gcagcataca tagttatagt
    22441 agctactgaa tcagggtcta aaaaccttgt gtctggagct atcaaatttt tatttggcaa
    22501 gtatatgtca tattctccat ttattataag ttctgaagtc aatcttaaaa tccatactcc
    22561 aggttttata tctcttaatc ttatctccaa attttctttt ccagaggtaa tatatggata
    22621 aataaatctc attgcataag tagtattttc taagttaaat tttcctctat atatataaaa
    22681 gtctggagaa taccttatat catgactaac ttcacctgaa ggagatatta tctgtgctcc
    22741 cactttatct ggaccattcg tatttagtgt tatatcaaga gcatagtcat ctccatcttg
    22801 tattattaca tcttgaactt ctcccacact gctaaatctg ccagaataat gaatatctgt
    22861 attcccttga tttcctgcac cactcactac taccacacca gcactactca atatattaaa
    22921 agtatctagt attgaagtag ttgctacagc acttgactta actccaatag tcaaatttat
    22981 tatcagtggt ttattttctg ttcttgctat gttagtaaca tacgttatag ctgctaaaaa
    23041 atctgaaaca ctgtaattta tccttccagc ataataagta tctgtatatg attttaattt
    23101 aactactatt aagtctgatt ctgtagtaat acctctgtac tgagaattta tccttccatt
    23161 tccaactaat ataccagaaa ctaaagttcc agtacctata ttatcttgac tcaaactccc
    23221 atcatttcta tttatggcta tatttaactc acttcttgta aattcacttc caaaaataaa
    23281 accttctgga ggtggatttg tatttgcttc ttggtcccat aaatataaaa ctttactagt
    23341 tccatcatca tttataaaat caggatgcaa ataatctatc ccagaatcta taactgctaa
    23401 taaaattcct ctccctgtta tatcattata tggattttca taaatataat cagtttcagc
    23461 tgctgttgta atggtttctc cattatttac attattagtt atttcaatta gactgctcat
    23521 tggttcagat tcttcccacc aagcaacttg tattatatta tttaaaatag tttcatcaaa
    23581 atctaaaggt acatatatta ctgcaagctg actatttaaa accatatacc tatttattcc
    23641 attttcttgt agggcagatt ctatatcacc ttgataaatt atacaataag atttttccat
    23701 aaatccctcc tatcttaaaa catcaaacat tcctctaaca tccaagagcc catatccaga
    23761 atttgtattt ggatatactg tgtttgaatc ttttctagca ccagcttgca taaaagtttt
    23821 tattttttgc acatatgctt ggtttggata tctaccgtca acaaaagtat attgaaaata
    23881 cattgcagca gcaccagctg catgtgcact tgctgctgct gtaccagtta tagttgcata
    23941 cgtgttccca ggataagcag ctattatatt aacacctggt gctactatat ctggttttaa
    24001 cctgtcttca atagttggcc ctcttgatga actttgccat aaactaccat taatagtatt
    24061 gtaggctcct atggttatta aatcatcttg aatcgcagga taatttatag tgtaaaaagg
    24121 gtctacctct ctaaatctag ttccactttt taaaagttct ctatttggaa ggtataagtt
    24181 atatcttcct gttataatat aaactcctac taatcgaatc ttccatacac ctctttttgc
    24241 attctttaaa gtaacattag taaattgctg tccagaaaaa gttgttgggt atatatatgt
    24301 tatagaatat tcagtcccct ctaaatcaaa taaacctgtt actttattat aatttgaaat
    24361 tccaacactt ttactttctt caccagtggg agatactatt attacatcag ctttatctgg
    24421 tctatttaac caaagttcta atgataattc ttcctcgtct tcatttaact ctaattcaac
    24481 ttcaacagaa cctccaacat atggtattat tccagatgta tgtgtctgtg tattgccctc
    24541 atttcctgct cctgccgtta tacataaccc tctagtaaag aacgcttttt cactattact
    24601 cctattggtt aaacctgcta ggctactggt acctaaagac atatttataa ctaatggtct
    24661 tccaagttca aaagcttttt tatatgcata ctgagatgca gcaaacaaca ttgcactatt
    24721 ataaaaatca tctatcttgc cgagttttat tattattagc tcagaatctt ctgctatacc
    24781 tgcatattca ctatttacat ttccaagccc tgcacatatc ccactcaaca tagttccttg
    24841 accaacttca tcctgagata gactagggtc attttctgcg atagctcgat ttatatcttc
    24901 tcgtgtatat tctgtcccaa tataaaaacc atcaggagga gttccttctt ttgtttggtc
    24961 ccataaatat actatttttg aagtgccatc tggataaata aaatctgggt gtagatagtc
    25021 tattcctgta tctgcaattg atattagagt ccctcttcct gttatattaa tattaggatt
    25081 atttttaaag aaatttacgc ccatttcttc tgttgcaact acacctccaa aagtacctcg
    25141 attaatttct ccaagtaatg tcatctttgt agtcgataca gttcttatga ttgaaggaag
    25201 ttgcaaaact cgttgtatgc tattatagtc tgtattattt atagatagta cacctaatga
    25261 atcacttatc ttaaaaaacc tttgactcat acctaaccca gctagttctt cttcaaattc
    25321 aggagtatgg actatatcta ttcctgatag tattcctgat tgtctacttg catttttact
    25381 tatataaatt tcattctcta agtcattatg tatttgcata ttataaccat ctataaactt
    25441 ataactattt tcctcatctt taaatgactt attaatactt ctatatccaa tatcctctgt
    25501 ttctaaatct tgatttatat tagatagagt gtacaaatct atatctgata aatttaaaaa
    25561 accaaatcct gatgaattat ttggataaga ttgattactt aatctccttg ctccctttag
    25621 aagtaatgcc cttaatttct gtgaatacaa aaataaatca tttccattta caattcccca
    25681 ttccataaac aatgaacaaa cccctgtaac atgaggtgta gccatgctag ttccagttaa
    25741 tgctccactt gtacctcctg gtaaaaaaga tactatatct tcacctggag ctaataaatc
    25801 aggtttaaaa acacctaatt gtgtatctcc ttcaccagaa aatatagata ctatatctgt
    25861 tcttgaatta aaactaccta ctgttataac tctacttgct gttccaggaa ctgttacagt
    25921 aagctcttga gtaggaatca gaaatctagt atttctattt agaccttcag aagttggcaa
    25981 atatatattt acattaccag ttactatatc tattggttca aatacaattt tccataaccc
    26041 aggagttatc tgtgtatttg aacttaattg tagagtaact cttcttgtga gagaatacgg
    26101 tgctataggg taaaaataac cagttattct agtttcaccc aaagtattcc ttatctcacc
    26161 tgaagttaga gagattgctt gtgtttgatt atttgatggg tttaccaaat gtacactaaa
    26221 atcatcaaca aaatctggcc atatatttat gtttaatata cgctctcctt ccccaactat
    26281 aaactcaact tcttctgtaa tattattttg aagcctaatc cttttatgac ctcctttatc
    26341 tgcattattt ccagctgcta caactatatt gtttttccaa aataaacaca tatcatctat
    26401 atattgttca aataaagatg ttcctctatg tgaaccttca ttacttccat aacttatatt
    26461 taatgtaaca ggcattctta attctaatgc cctatctaaa ataaatttaa ttgccctcat
    26521 aaactctgta cttctcgaaa aaatatcggt ctgtatattt ccaactctaa ccactattat
    26581 tctggcatca cttgcaatag ttgcacaaat acctgcaaca tgtgtcccat gtaagctagt
    26641 tgttgaaata ggtatatata tacttccatc tattgcatta tttatatctt cattagtata
    26701 taatgttcct tctctaaaac cttctggtgg atttccttga atagattggt cccaataata
    26761 taatatctta gaccttccat cactatctct aaacacaggt agagtataat ctattcccga
    26821 atcaattata ccaattatag ttccttttcc agttaaacca gttctatttt taaatcctgt
    26881 tattcctgta cttgaaaaac tttgcacatc ctgagtctgt aatataaaag gcttttctat
    26941 aaattcaatt tctggataag ttaaaagtat atttacatct tcttcattac ttgatgttat
    27001 tattgcatat gatgaattaa gtatctctac tgatacacct aattcttctt ctaacctcaa
    27061 tatatctcca ttgtatttta caattaattc ataatttatt ataatcacct cgacttctaa
    27121 aattattatt aatgtatatg ttttgtgtga gtctaaaatg tattagacta tataattttt
    27181 taagtttcag ttatacaatt tataatagat atattaaaaa aaataaataa tgatggtaca
    27241 attttgaata aatcatacca tcatttatat ttactttatc ttgaaaccat taaatttttc
    27301 aatgctttct caagaccttt tacagtcaat ggaaacatat taaattcact ttgtatcatt
    27361 ctttgagttt gataccaata attaattgaa tcccatccat ctctaagttc tggattcatc
    27421 catacaattt tactgtactt tctcttaaac cttttaagcc actctatacc aggtgtgtaa
    27481 ttatatggac cacgatagtt accaccaata tgaagcaact cagaaggcga catagaagca
    27541 tctccaacaa ttataacttt atagttttta tctatatttt ttaatatcca ttcagtatta
    27601 atatatttac ttaaccaaca ttcaggtgtt gtaaataatc tatcataaat acagttatgg
    27661 aaataatata tctttacatc tttaaaatga tttgatttac ttacagactg aaataatgta
    27721 ttacataaag tgctataccc tctcattgaa ccacctgaat ccataagcaa taaaagcttc
    27781 actgtatttt ttcttggctt ctcaaaaaat aactttaaat atcctgcatt attacaagtc
    27841 tcttcaatag tcttatccaa atcaagttct gtctttggag catctattct agtagaaaat
    27901 tgacgaagtc tctttagtgc aacttgaaat tgacgcatat ttaaaacttc atcatctcta
    27961 aaatctctgt attttctttc tcctgcaact tcaagaacag ctctaccata agtagaattt
    28021 ccacctatac gtataccagt ttgccctttt cctgaatgtc ctaactctga agtgcctcct
    28081 gtgcctatcc aataattacc accattatga ggagagtctt gttcttttat tcgttcctcc
    28141 aatttagctc ttaatttatc aagatttata tttggatttt gttctaatct ttcaaactct
    28201 tctaaatcta tatctggttt tttaagccaa ttcataatct cttctggaat ttcttcttgg
    28261 tgttctatac ctttaaaata ctccaaaaac actgcatcaa acttatcaaa atcactttca
    28321 ctttttatta aaatcatcct gcaaagatag taaaaatttg aaaagtttga atagcacagt
    28381 cctttatcca atgcttcaat taaagtcatc cattcattta aagatacatt taatcctctt
    28441 gacctcaata aataaaaaaa ttcaataaac ataattatcc agctcctatt aactataagt
    28501 gtctttgcat agattcaata tcctcattat tcttaagtag tattcctgca aaaggaactt
    28561 ctttttctat tttttcaata ggcattccac tcaaagttaa tgcttgtatc cagtctatta
    28621 actctgatgt actaggcttt ttttgtatgt cctttaaact tctaatccaa taaaaagtag
    28681 tcattacttg ttccaatagg tgttcttcta ctttatcaaa atgtacttta actatttctt
    28741 ccatcatgtc tctatcagga aattctatat aatgaaatat gcatcttctt aaaaaagcat
    28801 ctggaagttc tttttccgca tttgaagtta taataactat tggtctttgt ttagctctta
    28861 cagtttcttt tgtctcattt atgtaaaact ccattttatc caattcccaa agcaagtcat
    28921 ttggaaattc taaatccgcc ttatctattt catctattaa aagaattact tgttgatttg
    28981 agctaaaggc ctctcctagt ttaccatatt ttatgtactt gctaatatca tctacacctt
    29041 ctcctccaaa ttggctatca taaagtcttt gaacagtatc atatacataa agcccttctt
    29101 gtgcttttgt agttgatttt atattccaaa ttactaaatc tttttttaat tcatttgaaa
    29161 ttgcttgtgc tagcatagtt ttacctgttc caggttcgcc cttaatcaaa agtggctttt
    29221 caagagcaat agcaacatta actgatgcca tcaattctgg tgatactaca taatcactac
    29281 ttcctctaaa gttagatatc tcttttttta tcataaatcc tactcctttt aaacagtatt
    29341 ttctaaatgt atatagactt tattactatt tttgatataa aaataataa
//
LOCUS       DAMJXI010000044        28594 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.046, whole genome shotgun sequence.
ACCESSION   DAMJXI010000044 DAMJXI010000000
VERSION     DAMJXI010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28594
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.046"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(234..2513)
                     /locus_tag="PC465_002509"
     CDS             complement(234..2513)
                     /locus_tag="PC465_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2649795.1"
                     /translation="MLSDAKNNRYGLSIIAVISILVITISCLIYGSRLNKTLGEETNQ
                     YLSEIANQSVNVLKKQINGDIKLLESISIFIEGEESFEVDNILSILKRQAINSSFKRM
                     GVILPNGTAYTTDGYIEDFSKRDYFLKSMQGEVVITGKLKDVIEDDKNTNSNINVYSV
                     PIYKDNEVKGVIFATHSTKLYEKILSVPTFNGKGYSYITRSNGDIVLNPSSKNANSTK
                     ENLFSYIGRSDSISKSSINNMKSNIKNFKSGSLSYSMFGKGYYLSYAPIGINDWYLFS
                     EVPKTAISEKSYAIIKLTLSACVVLIIIFTALTIYILFIHKKSKEKLEEFAFKDNVTG
                     IGNSNKFNLEGGKFLSSHEKKNLVLIYFDIDKFKLVNDRFGYEEGDRVLKEIAEIIKN
                     IFKEQSVFSRISNDNFAIIFEKKNNRESIIEICELIRKKLSMIKTSLGVELNLIPSIG
                     VYFVEEGETNISTCLDKAMIAKTTVKRKYLKVYEIYAENLKETLIEERDIEQEMHDAL
                     KNEQFKVYLQPKVDLSTTKIVGAEALVRWQHPKKGLISPGVFIPIFEKNGFITELDMF
                     VFTQVCKNFKRWENENFPTFPISINLSRVHLENPGFISELERITKEYEVEPNLIEIEL
                     TESAIFDNTKILFKIMQTLKSVGFKISMDDFGSGYSSLNMLKDMPIDVLKLDRQFFIT
                     VGNAKKSQIVVSSIVQMAKQLDIKVVSEGVETVEQAEFLRFIGCDMAQGFLFARPMPI
                     EEYEKLILDRYSLNRKETN"
     gene            complement(2784..4238)
                     /locus_tag="PC465_002510"
     CDS             complement(2784..4238)
                     /locus_tag="PC465_002510"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HDF2649796.1"
                     /translation="MKLNDIIQGLDIINVKGELNIDINNVQYDSRKVTKGTLFICIKG
                     FVSDGHKYIKDAIEKGASAFLVEEDVEIKGCTFIKVKDTRKDMAKVADNFYNHPSQKF
                     NVIGVTGTNGKTSITTILNEILTLNKNKVGLIGTIKIFDGEKDIVSNSTTPESIDLQY
                     HFNNMLDNGCDYCAMEVSSHSLALNRVDETDFKLGIFTNLTPDHLDFHKDLEDYRKAK
                     EKLFFKTTMANIINIDDEGGKKIYENIKGINVPCYTYGVDTKADFMARDIKSDSDGVS
                     YRLITPSYEEVIFIPVPGMFTVYNTLAVIAACYVLGIPKPIYKEGLRLSNGVSGRFET
                     VPNDKGISVIVDYAHTPDALENVLKTTQQFAEGKIISVFGCGGDRDTEKRPLMGAIGQ
                     KYSDLCIITSDNPRTEEPEAIIKDILEGIDKKKENYHVVVDREQAIAEAISMAKKDDV
                     VIITGKGHETYQIIGKVKHHFDDKEVANECLSKM"
     gene            4402..5271
                     /locus_tag="PC465_002511"
     CDS             4402..5271
                     /locus_tag="PC465_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2649797.1"
                     /translation="MDNKIGYLNDNFKIFNIRDKKDIQFEYHNHDFNKIIIFINGNVT
                     YFVDGIPYKLKPWDILFISNNEIHKPVIDSNVFYERIAIWISPEFMKKNSDANSDLEK
                     CFKIATENKCNRLRLNIHDIESIKSFIEQINISESNTEFGNEILRNTLFIQLMIFLNR
                     IFLKNENMESTEDVFYDETIKKVLNYINSNIDDKLSIDSISSEFFISKYYLMRKFKSH
                     TGTSIHNYIVQKRLILAKSLITNGHLMSEVCNKCGFNDYSSFVRAFKKNYGVSPKNYI
                     NNKNPLDITLLDE"
     gene            complement(5484..7556)
                     /locus_tag="PC465_002512"
     CDS             complement(5484..7556)
                     /locus_tag="PC465_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2649798.1"
                     /translation="MKKVFGVLQKVGKSLMLPVALLPAAGILLGVSNALAGDALLAHF
                     PALANPTFQLIISIMESSGQIIFNNLPLIFAVGVAVGLTEGEGVAALAAIVGFLILNT
                     SMGVMAGVTEDMVDNSMYANIVGIPTIQTGVFGGIIIGIVAAYLYKKFYKIELPQYLG
                     FFAGKRFVPIVTSLVAIAIGIILSFIWPPIQEGLLSFSKNVIEANQTLAAFMEGSLER
                     LLIPFGLHHVFHNPFWYQFGEYVNKAGELVMGDQKIFFAQLKDGVNFTAGTFMTGAFP
                     FMMFGLPAAALAMVHEAKPEKKKFVAGIMASAALTSFLTGITEPIEFAFLFVAPVLFA
                     IHCLFSGLSYAIMQLLGVKIGFTFSGGLIDFLLFGVLPNRTPWYLAILVGIGFAVLYY
                     SVFRFMIRKFNLKTPGREDESETNAEVIEMSKNELASEILIALGNKDNLKSLDACITR
                     LRLVVNDINKVDKEKLKSLGAAGVMVIGNNVQAIFGPKSDSIKSDIKDIIEGKTKVES
                     TVTKNVDKNKVKKNMEVANMENALVEKIDSLTNGEILDIEEVPDSVFSSKLMGDGFAI
                     KSSDGLIYSPVDGTIGVIFPTKHAIIIKSQKSGVEILIHLGIETVNLEGNGFEVFVNV
                     GDEVKAGEKLVKMDLEYIEKNGLSTISPVVFTNLEQNQKLSIKKGVTTAKEENRVSIL
                     RDDIEKIG"
     gene            complement(7859..8701)
                     /locus_tag="PC465_002513"
     CDS             complement(7859..8701)
                     /locus_tag="PC465_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2649799.1"
                     /translation="MIIQQIYNNNVVLVLDENIKKELILTGCGIGFQKKKGQEIDKSK
                     IERTFVIQDESFLDKISKLASQVDEKFFEVSTEIIAYAEENLNTKLYEYIYVALTDHI
                     AFAIKRYHENITIKNDLLHEIKRIHKKEYEIGKWAVDYINKEFDVKFPVDEAGFIAMH
                     IVNSNYKGSSKESLLITKIVKDILNIIRYYYRVEFKEDDINYDRLLTHLKFFAKRLVK
                     KEKINDTNNEIIDIIKVKYEKDYDCAYKIKTHVEKNYDYYVSQDELLYLTLHIKRVIS
                     VLNL"
     gene            complement(8962..11004)
                     /locus_tag="PC465_002514"
     CDS             complement(8962..11004)
                     /locus_tag="PC465_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HDF2649800.1"
                     /translation="MSILVTLLGLLVCTTISTVFSKKWSNIPLAIYQIVLGIILSILP
                     FKFSFSFNPEIFVICIIAPLLFSEGQNVSRKELLELRKPILLLAFGLVLITVFAGGIF
                     IHFLIPGMPLSVSFALAAVISPTDLVAVKSIAQGLNFPKNMMSILEGESLLNDAAGVV
                     AFKVAVLATVTGVFSIEEAGIQFMITAFGGIIVGSILGYIIIKIRLSLHKWNLEEIPM
                     VIVIQIMTPLFVYFVAEEIGVSGILAVVMAGIAHGIEKEHLQNTTTKLRIISDNTWYV
                     LEYVLNGFVFTLLGFLLPSIYTGLSSKNENMALELTFISTLIVLILFVIRFIWVYLWH
                     NSFIKPKKNPLNNFFVGFLGFKDEEVVKESISKCKYSLIVATCGVHGTFTLATALSIP
                     FYLADKDVFPMRDTVLFISSEVILISLVLATVLLPRLLKNNVQESEPLLSDKEAYKLI
                     LKEAILKLSNEKAQEVQPVIHDLNEQLVDSEKGILNTPDNKLISMMIAEADQQGLLAV
                     LKLLEDGKISDRAFKLYRFYITKSRKSVQKSIFKIVKLKISMWIINRKVKKEVKEKIT
                     KIVSENKEIIKEFHHAYALSTKTAISFINKNTDEDNRHEALIAIRFYNRYLNWITRKI
                     QNDDKFEARVEYYRVMAIQSQRDSVQQLVETKQISREVAKELLENILYDEMMMIES"
     gene            complement(11156..12127)
                     /locus_tag="PC465_002515"
     CDS             complement(11156..12127)
                     /locus_tag="PC465_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HDF2649801.1"
                     /translation="MKKEESLLKVEGLKKYFEVKSGLFDKEIKCVKAVDGISFDLKKG
                     ETLAIVGESGCGKSTAGRTILRLIEKTEGKVEFNGVDIYKLEKEELRKLRPKMQMIFQ
                     DPYSSLNPRLNVEQIISEAVIEHNLVPKNEIKDNILNVVESCGLSKYHLNRKPGEFSG
                     GQRQRIGIARALALNPEFIVCDEPVSALDVSIQSQIINLLMDLQDKYKLSYLFISHDL
                     SVVNHIAHRVCVMYLGSIIEIATKGELYLHSQHPYTKALMSAVPIQDPTIKKNRIILK
                     GDIPSPTNPPSGCKFHTRCPYCKEICKKEIPVLKEISRNHFVACHLV"
     gene            complement(12128..13105)
                     /locus_tag="PC465_002516"
     CDS             complement(12128..13105)
                     /locus_tag="PC465_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2649802.1"
                     /translation="MSKALIEVKDLKVYFHTDKGIVKSVNEVSFNINEGETIGIVGES
                     GCGKSVTAMSLMKLLPTSKIEGGEIIFRGKDILKMNEDELMGIRGNEISMIFQEPMTS
                     LNPAFTIGSQIIEGIMIHQDLSKEEAKKKVIDMIKLVEIPRAEEIYNSYPHELSGGMR
                     QRIMIAMALSCNPKLLIADEPTTALDVTIQAQILDIMKNIKEKLNTSIMMITHDLGVV
                     AEMCDKVLVMYAGKIIEVAEVVELFKNPKHPYTIGLLKSKPALGKNKDKRLYSIPGQV
                     PNPIGMPDSCYFSDRCEKVCDKCRTQIPPLIELNSGHSIACWLYKKEEI"
     gene            13324..14883
                     /locus_tag="PC465_002517"
     CDS             13324..14883
                     /locus_tag="PC465_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2649803.1"
                     /translation="MKFKKLASLILVSSLMLTFTACASNDKDKSSGSKSGGTVVIPMA
                     SDPDIINGAFANVKEDSLASNIVYAPLYTYEKGNLVNYLAEKVDFKDSKELTIKLKSN
                     LKWHDGKPITAEDVLFTFNTVLDEKQNSPSRQYLLVGEKPVKVEKIDDLTVKITLPTA
                     SESFLYGISKISPIPKHVFEGESNIAKSEKNNNPVGSGAFKFKEWKKGESIVFEKNAD
                     YFGGEPKADSIALKIIPNEASQEAALNNGEISLMKTSAEGYEKAKSNSNLQTYTYSEE
                     RLNYIVFNQNISNMANKEVRQALSYALNRNEMIESAYGKEGSVPAKSILVPEADFYTE
                     EGVEGYDQDTNKAKDLLDKSGVKIDKLKIGYNTGRFGHKNYALVAQQELKKIGIEAEI
                     VPYESKAFFNILFSNSTECDMYVNGYAWGLEPNPYRGMFETGQYCNQTKYSNAEIDAL
                     WEKGFTELNKEKREEIYKQIQQDISKDAPIYTIDYEQNLMAAQKNLKGIKDAKPSPAI
                     LFEDWSKLYVE"
     gene            14989..15948
                     /locus_tag="PC465_002518"
     CDS             14989..15948
                     /locus_tag="PC465_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2649804.1"
                     /translation="MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMS
                     SQDIENIRVNMGLDKPVYIRYLNWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILM
                     GTSLIFSILVAIPLGILLAVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLN
                     IFPSGGMHTIGNDSIGDLVKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITAR
                     AKGLSEKVILFKHVLKNSLTSLVTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIF
                     SRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF"
     gene            15951..16763
                     /locus_tag="PC465_002519"
     CDS             15951..16763
                     /locus_tag="PC465_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2649805.1"
                     /translation="MFTSILKKLKKDKSFAFACITLSIIIILIIASFILNIDSNAIDT
                     TSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYI
                     GGKLDQFLMRLVDMLMSIPSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGET
                     LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGL
                     GIQLPLASWGNMLQDAQRHIFDKLYLAVFPGLLIFLTVMSLTIISKKFSSNT"
     gene            complement(16975..17877)
                     /locus_tag="PC465_002520"
     CDS             complement(16975..17877)
                     /locus_tag="PC465_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2649806.1"
                     /translation="MDIKQLKYFVEIVKSGFNLSIASKTLHISQPALSQIIKNFEESE
                     DVYLFERYKGRLNGLTPAGERFYVNAEHIINEYKNMMEDLREDSVQFKGKVRIGIPPL
                     ILGIAFSDVVAQLVANNPDIEFDIVEKGAYDLNRMLILQELDYAVLLHPHKIDKSVVT
                     EHVLQEDELTAFLNINHPLAKKDKIDWNDLNEQLLAIFNPTFMIHHKLMQKFTDENVK
                     LKRYIMSGSWDFLLLSTTNSDFITILPSPVHDFFENSKIIEKPFNHPITWKVILCRPK
                     KERYSHVDQHVFKFIIDFFSKKNS"
     gene            18232..19410
                     /locus_tag="PC465_002521"
     CDS             18232..19410
                     /locus_tag="PC465_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HDF2649807.1"
                     /translation="MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTIAVKEAISRVRLN
                     LSEIDEVIIGNVLQTGLGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSI
                     TSGENDVVIAGGTENMSQAPYIVPTARFGSKMGDITMVDSMLTDGLIDAFNQYHMGIT
                     AENIATKFEFTREMQDKLALESQNKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDE
                     YPKLGMTFEGLSKLKPAFKKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKI
                     KSYASAGVEPEVMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQID
                     SSKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVETGLATLCIGGGQGISMVVSR
                     "
     gene            19419..20075
                     /locus_tag="PC465_002522"
     CDS             19419..20075
                     /locus_tag="PC465_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HDF2649808.1"
                     /translation="MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIK
                     DLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTL
                     AEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
                     AGNLVYKGSMNNFNNLMASAAKITIVEADEIVEIGDIDPNEVNTPGIFVNYIVEGGNL
                     "
     gene            20075..20740
                     /locus_tag="PC465_002523"
     CDS             20075..20740
                     /locus_tag="PC465_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HDF2649809.1"
                     /translation="MDKLEMQEYIANRVSKELKDGAVVNLGIGLPTKVANYIPDNVNV
                     ILQSENGFLGLGSAEDGNSSDETIVNAGGQPVTILPGGCFFDSATSFGIIRGGHVDIT
                     VLGALQVDKYGNIANYMIPGKMVPGMGGAMDLVTGAKKVIVAMEHTSKGSAKILNNCT
                     LPLTATNAVDLIVTEMGVMEVTSDGILLKEINPAFTLDDVISATEAPLILSDSLNGKI
                     SVV"
     gene            20845..21621
                     /locus_tag="PC465_002524"
     CDS             20845..21621
                     /locus_tag="PC465_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HDF2649810.1"
                     /translation="MVKDKVVFVTGAASGIGKQIAESFLKNGAKVMFSDINQEALNNT
                     ITELQKKGYDCMSVKCDVTKEEEINHAIDKTVEKYGRLDILINNAGLQHVSMIEDFPT
                     DKFEFMIKIMLTAPFIATKKAFPIMKKQGFGRIINMASINGVIGFAGKAAYNSAKHGL
                     IGLTKVAALEAADSGITVNALCPGYVDTPLVRGQFNDLSKTRNIPLENVLEEVLYPLV
                     PQKRLLDVQEIADYAMFLASDNAKGITGQACLLDGGYTAQ"
     gene            21683..23017
                     /locus_tag="PC465_002525"
     CDS             21683..23017
                     /locus_tag="PC465_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF2649811.1"
                     /translation="MSIIAPIGIIIGIIAIIYFSVKEIHITIAAPIATLIVVILNKMD
                     VVTSMLGADKNNYMGALGNYIMSYFAIFLLGSILAKFMEESGATVSIADFILNKFGSN
                     HPYRVLVAIFIVSFILTYGGISLFVVMFAVIPLARTLFKKLDISWNLIQIPLWLGIAT
                     ITMTIIPGTPAIQNVIPIQYLNTSLTAATIPSIVGSIGCATFGLVYMKYALNKSIRKG
                     ETYATYTSELEEESLDRELPGFFASIFPLLALVIIAITGSTFGSEFMKKNVIYIALIV
                     AILLSAFLFHKFLSSKIQTLSIGASGSIGPIFATSSAVAFGAVIMAAPGFDVFSKLIM
                     SIPGSPLISLTVLTSTMSAITGSSSGALGIVMPNFADYYLSTGLNPELIHRVATIASN
                     ILTIVPQSGVFLTFLSLSKLTHKTGFKETFIVVAVGSLIAEIIVITLGLLMY"
     gene            23514..24440
                     /locus_tag="PC465_002526"
     CDS             23514..24440
                     /locus_tag="PC465_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein"
                     /protein_id="HDF2649812.1"
                     /translation="MMRRNIPTKLKTILALGVLTLATASSAVTASASSLENNVNISNK
                     SLVYSNTKYKFSAKPNCSVKPELKPDKDNSCKDKNHNDKNCNNTNKPEDNNNSDSTNK
                     PDNNKPESNKPEDNNNSGSTNKPDNNKPESNKPEDNNNSGSTDKPDNNKPESNKPEDN
                     NNSDSTNKPDDNNNSGSTSESFSAYQKEVVDLVNIERAKAGLNPLTLDSSISNVATKK
                     SQDMIDNNYFSHNSPTYGSPFDMLKKFGISYKTAGENIAMGQKTPKEVVNAWMNSEGH
                     RKNIMNPNFSKIGVGVAQKSGGSIYWTQIFVG"
     gene            complement(24833..28372)
                     /gene="nifJ"
                     /locus_tag="PC465_002527"
     CDS             complement(24833..28372)
                     /gene="nifJ"
                     /locus_tag="PC465_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HDF2649813.1"
                     /translation="MAKFMKTLDGNTAAAHVAYAFTDVAAIYPITPSSTMAEVVDEWA
                     SQGRKNIFGQTVNVVEMQSEAGASGTFHGSLQGGALTSTFTASQGLLLMIPNMYKVAG
                     ELLPGVFHVSARALASQALSIFGDHQDVMAARQTGCVLLASGSVQEVADIAPVAHLAA
                     IEGRLPFIHFFDGFRTSHEIQKVELLENEDYASLLNFEAVQAFRDNALSPNHPVARGT
                     AQNPDIYFQTREASNKYYQNIVGIVEKYMEKMSNLTGRKHSLFDYYGAEDAKYVLIAM
                     GSVTETIEETIDYLNAKGEKYGLVKVHLYRPFSMKHFLDAMPSTVERICVLDRTKEPG
                     STGEPLYLDVRDVFYGKENAPMIIGGRYGLGSKDTTPSDIKTVFDNLVSEQPKNGFTV
                     GIVDDVTNTSLTPSEPIKIASKGTIRCKFWGLGSDGTVGANKQAIKIIGDHTEKYAQA
                     YFDYDSKKSGGITMSHLRFGDTPIRATYLIDEADYIACHKQSYVYQYDLLKGLKKGGT
                     FVLNTIWDQAGLEEHLPAHMKQYIAKNDIKFYTVNAVKLGQEIGLGNRINMIMQSAFF
                     KLAEIIPEEDAVKYLKDSIVKAYGKKGEKIVNMNYAAVDAGINALVKVEVPASWENAV
                     DADKGEVKEPEFIKNILRPMTAQEGNNLPVSTFNGIEDGTFPCGTAAYEKRGIAVDVP
                     EWIIDNCIQCNQCSFICPHSCIRPVLVTEEELANAPEGFEAKKALGKGLEGLKYRMQL
                     SPLDCTGCGNCADICPAKEKALVMKPIDTQLDTELDNWAFAVNPDEVAPKGDVMPANT
                     VKGSQFRQPLMEFSGACAGCGETAYIKVVTQLYGDRMMIANATGCSSIWGASAPSIPY
                     TCNHEGKGPSWANSLFEDNAEYGFGMYTAVKQIRNKIVDAMTELVSMDICEDAKAVFT
                     EWLDSRNDGEASKVASAKVVELLEKPACDCTDEKAKELVKAIKDRKDYLVKRSQWILG
                     GDGWAYDIGYGGLDHVLASGEDVNVLVFDTEVYSNTGGQASKATPAAAMAKFAASGKK
                     SRKKDLGMMAMTYGNVYVAQVAMGADKNQFIKAVIEAEKHDGPSLIIAYAPCINHGLK
                     EGMGRTVANEAQAVACGYWHLYRFNPEVKAEGKNPFTLDSKEPTASFKDFILAQVRYS
                     AIAKQFPEEADGLFAKAEADAKERYEGYKKLAE"
BASE COUNT         9844 a         4563 c         3743 g        10444 t
ORIGIN      
        1 attactatta ttactatcta aagtattttg ctataatccc atatactctt acctcaaaaa
       61 cattcaaata gaaaaaatac tacataatta ataaactttg cccaataatt cctaaaataa
      121 tatcataaca atgatttatg ttttataata gtatattttt acataaaaaa gtgaacattg
      181 attaacaaag ttcacttttt tataaatttt tatgttataa ttcacaattt tatttaattt
      241 gtttcttttc tatttaaact atatctatct aatattaatt tttcatattc ttctattggc
      301 attggtctag caaataaaaa tccttgagcc atatcacaac ctataaacct taaaaactct
      361 gcttgctcta cagtttcaac accttctgaa acaactttta tatcaagttg ctttgccatt
      421 tgaacaatac ttgaaactac aatttgactc ttttttgcat ttcccactgt tataaagaat
      481 tgcctatcta atttcaatac atcaattggc atatctttaa gcatatttaa agaagaataa
      541 ccagaaccaa aatcatccat agaaatttta aatccaacag atttcaaagt ttgcattatt
      601 ttaaataata tttttgtatt gtcaaatatt gcactttctg tcaattcaat ctcaattaaa
      661 tttggttcaa cttcatattc ttttgttatt ctttcaagct cagaaataaa gcctggattc
      721 tcaagatgta ctcttgataa gtttattgat ataggaaatg tggggaaatt ttcattttcc
      781 caacgtttaa aatttttaca aacttgggta aatacaaaca tatccaattc tgttataaaa
      841 ccatttttct caaaaatagg aataaataca cctggactta ttagaccttt tttaggatgt
      901 tgccaacgta caagtgcttc agcacctaca attttagtag ttgataaatc aaccttaggc
      961 tgtaaataaa ctttaaattg ttcatttttt aaagcatcat gcatttcttg ttcaatatca
     1021 cgttcttcta tgagagtttc ttttaaattt tcagcataaa tctcataaac ttttaaatat
     1081 tttcttttta ctgtagtttt tgcaatcata gctttgtcaa gacaggtaga aatatttgtt
     1141 tctccctctt caacaaaata tacacctata gatggaatta aattgagttc tactcccaaa
     1201 cttgttttta tcattgacaa ttttttacgt ataagttcac atatttctat aattgactct
     1261 ctattatttt tcttttcaaa tattatagca aaattgtcat ttgaaattct tgaaaataca
     1321 gattgctctt taaatatatt cttaattatc tctgctattt cctttaatac tctatctcct
     1381 tcttcatacc caaacctatc atttactagc ttaaacttat ctatatcaaa ataaattaaa
     1441 actagattct ttttctcatg agaggataaa aattttcccc cttcaagatt aaatttattt
     1501 gaattgccaa tacctgtaac gttatcttta aaagcaaatt cttccaattt ttccttactc
     1561 tttttatgta taaatagtat ataaattgtt aatgccgtaa agattataat caagactaca
     1621 catgctgata atgtaagttt tataatagca tatgatttct cagatatagc agttttagga
     1681 acttcagaaa aaagatacca atcattgatt cctattgggg cataacttaa ataatatcct
     1741 tttccaaaca tactataact taatgaacct gatttaaagt tttttatatt tgacttcata
     1801 ttattgatac tagattttga tattgaatca cttctgccaa tgtaagaaaa taaattttct
     1861 ttagtagagt tggcgttttt actgcttgga tttaaaacaa tatcaccatt acttctagtt
     1921 atataagaat atccttttcc attaaatgta ggtacagaaa gtattttttc atacaacttc
     1981 gtactatgtg tggcaaatat aactccttta acctcattat ctttataaat tggtacagaa
     2041 tatacattaa tattactatt ggtattttta tcatcttcta ttacatcttt taattttcct
     2101 gttataacca cttctccttg cattgatttt aagaaataat ctcttttaga gaagtcttct
     2161 atataaccat ctgtagtgta tgctgtacca tttggtaaaa taactcccat tcttttaaat
     2221 gaactattaa tagcttgtct ttttagtata gaaaggatat tatctacttc aaaagactct
     2281 tctccttcaa taaatattga aattgactct agtaacttta tatctccatt aatttgtttt
     2341 tttaacacat tgacgctttg atttgctatt tctgaaagat attgattcgt ttcttcacct
     2401 aatgtcttat tcaaccttga accataaatc aaacaggaaa ttgtaattac taagatactt
     2461 atgacagcaa ttatggacaa accataccta ttattttttg catcacttaa cattatgctt
     2521 cctgcctttc tcgaatctat gtatgtataa tcattatctt atgacaatta ttgtaaacat
     2581 tttataataa tacttatttt tccatattta ctgtaattat acaaaattat aaactttatt
     2641 acaacaataa attaattaat atagatatta gtgtttatat tattgcatta tctattttac
     2701 aattatttac atataaaaaa atgtaatatc aaagtgaagc ttgatattac atttttgttc
     2761 ttgtattttg tttaattttt atgctacatc ttacttaaac actcatttgc aacttcttta
     2821 tcatcaaaat gatgcttaac tttacctata atttgataag tttcatgtcc cttacctgtt
     2881 ataattacaa catcatcctt ttttgccata cttatagctt ctgctatagc ttgttctcta
     2941 tcaacaacaa catggtaatt ttcttttttc ttgtcaattc cttcaagtat atcttttatt
     3001 attgcctctg gttcttcagt tcttggatta tcagaagtta taatacataa atcagaatat
     3061 ttttgtccaa ttgctcccat caaaggtctc ttttcagtat ctctatctcc accacaccca
     3121 aacacagaaa ttatttttcc ttctgcaaat tgttgagttg tctttagtac attttcaagt
     3181 gcgtcaggag tatgagcata gtctacaatt acgcttatac ctttatcatt tggaactgtt
     3241 tcaaaccttc ctgatactcc attagaaagt ctaaggcctt ctttatatat tggtttaggt
     3301 atgccaagta catagcaagc agctataact gctaaagtat tatatactgt aaacattcct
     3361 ggaactggta taaatattac ttcttcatat gaaggtgtta ttaatctata agatactcca
     3421 tccgaatctg attttatatc tctagccata aaatcagcct tagtatcaac accataagtg
     3481 taacaaggta catttatacc ttttatattt tcatatatct tttttccacc ttcatcatct
     3541 atgtttatta tatttgccat agtagtctta aaaaataatt tttcttttgc ttttctataa
     3601 tcctctaaat ctttatgaaa atctaaatgg tctggtgtta aatttgtaaa tatgcctagt
     3661 ttaaagtctg tttcatcaac tctatttaat gccaatgaat gtgatgaaac ttccatagca
     3721 cagtagtcac atccattatc caacatatta ttaaaatgat attgtaaatc tatactttct
     3781 ggagttgttg aattggaaac aatgtctttt tctccatcaa aaatttttat agttcctata
     3841 agtccaactt tattcttatt taaagttaat atctcattta gtatagtagt tatactagtt
     3901 tttccattag tacctgtaac tcctataacg ttaaattttt gagatggatg attgtaaaaa
     3961 ttatcagcta cttttgccat atcttttctt gtatctttta cctttataaa tgtacatcct
     4021 tttatttcta catcttcttc aacaagaaat gcacttgctc ccttttctat ggcatctttt
     4081 atatacttat gaccatctga cacaaatcct tttatacata taaataatgt accttttgta
     4141 acctttcttg aatcatattg tacattatta atatctatat ttaattcacc cttgacattg
     4201 attatatcca acccctgtat aatatcattt aatttcataa atgctttcct ccctttaaac
     4261 tctttctgct aaaattacac tacatataat attatattaa gaatttttta ctatgtgaat
     4321 ggttaaaaat gcttgaaaca ttgcaaaaaa tgctctataa ttttctataa tataactgag
     4381 gaaaggtctt ctataaaaac tatggataat aaaatcgggt acttaaacga taactttaaa
     4441 atatttaata ttagagataa aaaagatata caatttgaat accataatca tgattttaat
     4501 aagataatta tatttataaa tggaaatgta acttattttg ttgatggtat tccctataaa
     4561 ctaaagcctt gggatatact ctttatcagc aataatgaaa tacataaacc agttatagat
     4621 tcaaatgtct tttatgagag aattgcaata tggattagcc cagaatttat gaaaaaaaat
     4681 agtgatgcta atagtgactt agaaaaatgt tttaaaatag ctacagagaa taaatgcaat
     4741 agattgcgtt taaatataca tgatattgaa tctattaaga gttttattga gcaaataaat
     4801 atttccgaat ccaatactga atttggaaat gaaatattga gaaatacatt atttatacaa
     4861 cttatgatat tcttaaacag aattttccta aaaaatgaaa atatggaatc aacagaagac
     4921 gttttttatg atgaaactat taagaaagta ttaaactata taaattcaaa tatagatgat
     4981 aagctttcaa tagatagcat atcgtctgaa ttttttataa gtaagtatta tcttatgaga
     5041 aaatttaaat ctcatactgg aacgtctata cacaattata tagttcaaaa aagattaatt
     5101 ttggcaaaat cactaataac caatggtcac cttatgagtg aagtttgtaa taaatgtgga
     5161 ttcaacgatt attctagttt tgtaagggca tttaaaaaaa actacggtgt atctcctaaa
     5221 aattatataa acaataaaaa tcctttggat attactcttt tagatgaata gataatttat
     5281 gtaaatttta ttttaataaa acttgaagta ttagtgtatt tatcttacta atacctcaag
     5341 ttttttaatg ttttaaaata tatcaaaata taatgatata tatttctatt acttaaaata
     5401 tatattaaat aaattgcatg ttaactgaac ctatttatat atttattaaa tctcacataa
     5461 cttttagtta cactatcata tagctatcct attttttcaa tatcatctct taatatactt
     5521 actctattct cctcttttgc tgtggttact ccttttttaa tgcttaattt ctgattttgt
     5581 tctaaattcg taaatactac aggacttatt gttgatagac catttttttc aatatattct
     5641 aagtccattt taactaattt ttctcccgct tttacttcat ctcctacatt cacaaatact
     5701 tcaaatccat ttccttctaa atttacagtt tctatcccta aatgtataag tatttctact
     5761 ccactttttt gggattttat tattattgca tgcttagttg gaaatataac tccaatagtt
     5821 ccatcaactg gtgaataaat caatccatca ctagatttaa ttgcaaatcc atcccccatc
     5881 agtttacttg aaaatacaga atctggcact tcttctatat ctaatatctc tccatttgtt
     5941 aatgaatcaa tcttttctac taaagcattt tccatatttg caacttccat attttttttc
     6001 actttatttt tatcaacatt tttagtaaca gtactttcaa cctttgtttt tccctctatt
     6061 atatctttta tatcagactt tattgaatcc gattttggtc caaatatagc ttgaacattg
     6121 ttgccaataa ccataacacc tgctgctcca agtgatttca atttttcttt atctacttta
     6181 tttatatcat ttacaaccaa tctaagtctt gttatacacg catctaggct cttcaagttg
     6241 tctttatttc ctaaagcaat caaaatctct gatgctaatt cattcttaga catttcaatg
     6301 acttcagcgt tagtttctga ctcatcttct cttcctggtg tctttaaatt aaattttctt
     6361 atcataaatc taaatacact atagtataat actgcaaaac caatacctac caagatagcc
     6421 aagtaccatg gagttctatt aggaagaaca ccaaataata agaaatctat taatcctcct
     6481 gaaaatgtga atccaatttt aactcctaat aattgcataa ttgcgtatga taaacctgaa
     6541 aataaacaat gtattgcaaa taatactggt gcaacaaata aaaacgcaaa ctctattggc
     6601 tcggttattc ctgttaaaaa agaggttaat gctgctgatg ccattatacc tgctacaaat
     6661 tttttctttt ctggctttgc ttcatgcacc atagcaagag ctgctgctgg aagaccaaac
     6721 atcataaatg gaaatgcacc tgtcataaaa gtacctgctg tgaaatttac tccatcttta
     6781 agttgagcaa agaatatctt ttggtcaccc attacaagct caccagcttt atttacatat
     6841 tctccaaatt gataccaaaa tggattatgg aaaacatgat gcaaaccaaa tggtattaat
     6901 agtctttcca aagaaccttc cataaatgct gctagtgttt gatttgcttc tataacattt
     6961 tttgagaaac taagtaatcc ctcttgtatt ggaggccaaa taaaagacaa tataattcct
     7021 attgctatag caactaatga agtaacgatt ggtacaaatc ttttacctgc aaaaaaacct
     7081 agatactgag gtaattcaat tttataaaac tttttataaa gataagcagc cactatccct
     7141 ataataatac caccaaatac ccctgtttga attgttggta ttccaacaat atttgcatac
     7201 atagaattgt ctaccatatc ttctgtaaca cctgccataa cacccataga tgtattgaga
     7261 attaaaaaac ctactatggc tgccaatgct gcaacacctt ctccttcagt taaaccaaca
     7321 gctaccccaa ctgcaaatat aagtggtaag ttattaaata taatttgacc tgaactttcc
     7381 attatactta ttataagttg aaatgtagga ttcgccaaag ctggaaaatg agccaacaat
     7441 gcgtctcctg ctaaagcatt actcacgcca agtaatatac ctgctgcagg aagtaatgca
     7501 actggtagca ttagagattt tcctactttt tgtaaaacac caaatacttt tttcatttac
     7561 ttttctctcc ttattatttt atattttttt aaataaaaaa gacttaagtt tataaaaagt
     7621 tacattagta tacttaattc taaaattaaa cttatgttaa tataaacaaa cctatattaa
     7681 cctaatttca gaattaaaaa taaactatta taattttttt ataaacataa gtcttgcctg
     7741 cattatcagt aacaatctta atgttttaaa attattattt tatattaaat tttaaataat
     7801 atattaaaat tgaacataat atattaaatc tatacattct gtattaaact actctttatt
     7861 ataaattcag tacagatata actcttttga tatgtaatgt taaataaagt agttcatctt
     7921 gacttacata gtaatcataa ttcttttcta catgagtttt tattttatat gcacaatcat
     7981 aatccttttc atactttact ttaattatat ctataatttc attatttgta tcattgattt
     8041 tttctttttt tactaatcgt tttgcaaaga attttaaatg agtcagaagc ctatcataat
     8101 ttatatcatc ttctttaaat tcaactctat aataatatct tataatattt agtatgtctt
     8161 ttacaatttt agtaattaac agtgattcct ttgaacttcc cttatagttt gaatttacta
     8221 tatgcattgc tataaaacca gcttcatcta ctggaaattt cacatcaaat tctttattta
     8281 tataatctac agcccatttc ccaatctcat attctttttt atgtattctt tttatctcat
     8341 gtagtaaatc attctttata gttatgtttt catgatatct tttaattgca aatgcaatat
     8401 ggtcagtaag tgctacataa atatattcat aaagtttagt attcaaattc tcctctgcat
     8461 aagcaattat ttcagtacta acctcaaaaa atttctcatc aacctggctt gctagtttac
     8521 taattttatc taaaaagctt tcatcttgta ttacaaaagt tctttcaatt ttacttttat
     8581 ctatttcttg acctttcttt ttttgaaacc caattccaca tcctgttaat attaattctt
     8641 tttttatatt ttcatctaaa actaatacaa cattattatt ataaatttgt tgaataatca
     8701 taatcaatat ctctcccaaa atacaatttc ccttattcat aaaaaaatac ctaaattaag
     8761 atacaattca cctgtatacc ttaacctagg tattgcctgc ttaccagtaa caatccagct
     8821 tgttaacgct tatatattgt attcaattta tggttttatt ctattataaa taaatatata
     8881 tgtcaagtaa attattgaaa actatttcct attttttagt attaatttta acatcaaaaa
     8941 tcaaatttta ttccattata tttatgattc tatcatcatc atttcatcat agagaatatt
     9001 ttccaataac tctttagcca cttctcttga tatttgctta gtttcaacta attgttgaac
     9061 actgtctctt tgactttgta tcgccattac tctgtagtat tctactcttg cctcaaactt
     9121 atcatcattt tgaatctttc tagtaatcca attcaaataa cgattataga atctgattgc
     9181 tattaaggcc tcatgtctgt tatcttcatc agtattttta tttataaatg atatagcagt
     9241 tttagtagaa agtgcatatg catggtgaaa ctctttgatt atttctttat tctcagatac
     9301 tatttttgta attttttctt ttacttcttt ctttactttt ctatttataa tccacatgct
     9361 tatttttaat tttacaattt taaatataga tttttgaaca gattttcttg attttgtaat
     9421 ataaaatcta tacaatttaa aggctctatc agaaatttta ccatcttcta atagtttcaa
     9481 aacagctaat aatccctgtt ggtctgcttc tgcaatcatc atacttataa gtttattatc
     9541 tggagtattt agtattcctt tttctgagtc taccaactgt tcatttaaat catgtataac
     9601 tggttgtact tcttgtgctt tttcattact aagttttaaa atggcttctt tcaaaattag
     9661 tttatatgcc tctttatcag ataataaagg ttctgactct tgtacgttat tttttaataa
     9721 tcttggcagt aaaactgttg ccaatactaa acttataaga ataacttctg atgatataaa
     9781 taaaacagta tctctcattg gaaatacatc tttatcagcc aaataaaaag gtatagataa
     9841 ggcagttgct agtgtaaatg taccatgaac accacaagta gcaactatta gtgagtattt
     9901 acatttagaa atactctctt ttacaacttc ttcatcctta aaacctaaaa aacctacaaa
     9961 aaaattattt aaaggattct ttttaggttt tataaaagaa ttatgccata aatataccca
    10021 tataaatctt ataacaaata aaataagtac aattaaagta gaaataaaag tcaattccaa
    10081 tgccatattt tcatttttac tactaagtcc tgtatatata cttggtaaca aaaaaccaag
    10141 cagtgtaaag acaaatccat tcaatacata ctccaaaaca taccaagtat tgtctgatat
    10201 tatccttaat ttagtagttg tattttgtaa atgctctttt tcaattccat gagctatccc
    10261 tgccattaca acagctagga ttccagatac tcctatttct tctgctacaa aatatacaaa
    10321 aagtggagtc attatttgta taactattac cattggaatt tcttccaaat tccacttgtg
    10381 taaactaagt cttattttta taattatgta tcctaaaata cttcctacta ttattcctcc
    10441 aaaagctgta atcataaatt gaatccctgc ctcttctatt gaaaaaactc ctgtaactgt
    10501 ggcaagtact gcaaccttaa atgctactac tccagcagca tcatttaata aagattcacc
    10561 ttcaagtata ctcatcatat ttttaggaaa atttaatcct tgtgcaattg attttactgc
    10621 tactaaatca gttggagata ttactgctgc caaagcaaat gaaacagata atggcatccc
    10681 aggaataaga aaatgtataa agattccacc tgcaaacacg gttattaaaa ctaaaccaaa
    10741 tgcaagaagc aaaattggtt ttctgagctc taatagctct tttctcgata cattttgtcc
    10801 ttcactgaat agtaatggag ctatgataca tattacaaat atttctggat taaatgaaaa
    10861 tgagaattta aatggcaaaa tagacaatat aatccctagt acaatttgat atattgcaag
    10921 aggaatatta ctccactttt tgctaaatac agttgaaatc gttgtacaaa ccaataatcc
    10981 caacaatgtt actaaaattg acataactac ctctcttttc aataataata ttatagatta
    11041 aacttatata tcaactaact taatattaac agcatgaaat cccatcttaa tcaaaaaaat
    11101 tttcagttta ttctattatt cttattatat acatcaaatt taatttttga aatatctata
    11161 ctagatgaca tgcaacaaaa tgatttcttg atatttcttt taaaactgga atctcttttt
    11221 tgcatatttc cttacaataa gggcatcttg tatgaaactt acatccactt ggtggatttg
    11281 ttggagatgg tatgtctcct tttaatataa ttctattttt cttaattgta gggtcttgta
    11341 ttggtactgc gctcataagc gcttttgtat atggatgttg agaatgtaag taaagttctc
    11401 ctttagttgc aatttctatt atagaaccta gatacataac acaaactcta tgtgcaatat
    11461 gatttactac actcaaatca tgagatataa ataaatatga aagtttatat ttatcctgta
    11521 aatccataag taaatttata atttgagatt gaatagaaac atctagtgca gaaacaggtt
    11581 catcacaaac tataaattct ggatttaatg ctaatgctct tgctatacct attctctgtc
    11641 tttgacctcc agaaaactca cctggttttc tatttaaatg gtacttagaa agaccacaac
    11701 tttctacaac atttaatata ttatctttta tttcattctt tggcactaaa ttatgttcta
    11761 taactgcctc ggatattatt tgttccacat ttaatcttgg atttaatgaa ctatatgggt
    11821 cttgaaatat catttgcatt ttgggtctta actttctaag ttcttccttc tctaacttat
    11881 atatatctac accattaaat tcaactttac cttcagtttt ttcaattaat ctaagaatgg
    11941 ttcttcctgc agttgatttt ccacatcccg attctccaac tatagccaaa gtttctcctt
    12001 tttttaaatc aaaagaaatt ccatctactg cctttacaca tttaatttcc ttatcaaata
    12061 atccagattt aacttcaaag tactttttaa gaccctctac ttttaataaa ctctcttctt
    12121 ttttcaatta tatctcctcc tttttatata accaacatgc aatactatga ccactattca
    12181 attctattaa aggaggtatc tgagttctac atttatcaca tactttttca catctatcac
    12241 taaaataaca tgaatctggc atcccaattg gatttggtac ttgtcctgga atcgaataca
    12301 atcttttatc tttgtttttt ccaagagcag gctttgattt tagaagtcca atagtataag
    12361 gatgttttgg atttttaaat aattcaacaa cctctgccac ttctataatt ttgccagcat
    12421 acatcactaa tactttgtca cacatttctg caactactcc caaatcatgt gtaatcatca
    12481 ttatagatgt gtttaatttt tcttttatat ttttcattat atctaaaatc tgagcttgaa
    12541 tagtaacatc taaagctgtt gttggttcat cagctataag taattttgga ttacatgata
    12601 aagccatagc tatcattatt cgttgtctca taccacctga taattcatgt ggatatgaat
    12661 tatatatttc ttcagctctt ggtatttcta ccagttttat catatcgatt acctttttct
    12721 tagcttcttc ctttgataaa tcttgatgta tcataatacc ttcaatgatt tgacttccaa
    12781 tagtaaacgc tgggtttaaa gatgtcattg gttcttgaaa aatcattgat atctcattcc
    12841 ctcttattcc cataagttca tcttcattca tctttaaaat atctttgcct cgaaagatta
    12901 tttctccacc ttctattttt gatgttggaa gtaacttcat caaagacatg gctgttacag
    12961 acttaccaca tcctgattct ccaactattc caatggtttc accttcattt atattaaaac
    13021 ttacttcatt tacactcttt acaatccctt tatctgtatg aaaataaact tttaaatctt
    13081 taacctcaat tagtgcttta ctcattattt tctcctctca gcaaaattac ttaagataac
    13141 atacaccttt tgattgtatt ttataaaaat ttaaattaca acattttctt acattttatt
    13201 atttttttct attaattata ataatataat agttaatttc tatatatatt gatttaataa
    13261 tgattactat tatacaataa aaaatatgtg ttaaatatta ttttatggag gttttataag
    13321 aatatgaaat ttaaaaaatt ggcatcatta atcttagttt catcattaat gcttacattt
    13381 acagcctgtg cttccaatga taaagacaag tctagtggaa gcaaatctgg tggaactgtt
    13441 gtaataccta tggcaagtga cccagatata atcaatggag cttttgcaaa cgttaaagaa
    13501 gactctcttg catcaaatat agtttatgct cctctttata cttatgaaaa aggaaattta
    13561 gtaaattatt tagcagaaaa agtagatttt aaagatagta aggaattaac tataaaatta
    13621 aaatccaatt taaaatggca tgatggaaag ccaataactg ctgaagatgt cttatttaca
    13681 tttaatacag ttttagacga aaaacaaaat tcaccatcaa gacaatactt attggtgggt
    13741 gagaaaccag ttaaagtaga aaaaattgat gatttaacag ttaagattac tttaccaact
    13801 gcaagtgaat ctttcttata tggtatatct aaaatttctc caataccaaa acatgtgttt
    13861 gaaggagaat caaatatagc taagtcagaa aaaaataata atccagttgg ttctggtgca
    13921 ttcaagttta aggaatggaa aaaaggtgaa agcatagtat ttgaaaagaa tgcagattat
    13981 tttggtggag aacctaaggc agattctata gcgctaaaaa taattcctaa tgaagcatct
    14041 caagaagcag ctttaaataa tggcgaaatt tcacttatga agacatctgc tgaaggatat
    14101 gaaaaggcaa aatcaaactc aaacttacaa acttatactt atagtgaaga aagattaaac
    14161 tacattgtat ttaaccaaaa tatatcaaac atggctaaca aagaagtaag acaagcctta
    14221 tcatatgcct taaatagaaa tgaaatgata gaatcagcat atggaaaaga aggttctgta
    14281 cctgctaaat ctatattagt tccagaagca gacttctata cagaagaagg tgttgaagga
    14341 tatgaccaag atacaaataa ggctaaagac ttattggata aaagtggtgt taaaattgat
    14401 aaattaaaaa taggttataa cacaggtaga tttgggcata aaaactatgc cttagtagct
    14461 caacaagagt tgaaaaaaat tggtatagaa gctgaaatag ttccttatga aagtaaggca
    14521 ttcttcaata tactatttag taatagcacg gaatgtgata tgtatgtaaa tggttatgct
    14581 tggggattag aaccaaaccc atatagaggt atgtttgaaa ctggtcaata ttgcaaccaa
    14641 actaaatatt ctaatgctga aatagatgct ttatgggaaa aaggatttac tgagttaaac
    14701 aaggaaaaac gtgaagaaat atataagcaa atacaacagg atatatctaa ggatgcgcct
    14761 atttacacta tagattatga acaaaattta atggcagctc aaaaaaatct aaaaggaata
    14821 aaagatgcta aaccatctcc tgcaatatta tttgaagatt ggtctaaact gtatgtagaa
    14881 taattgatgt aaaattttat attattaatt agaaaaggag atgtctaaaa ataatattgt
    14941 tttattattt taaaacgaga catctctttt aattaggaga atttacttat gttaaaatta
    15001 atattgaata gagtaaaagt tttaatacct atgttaatct taatatctat attatcattt
    15061 ggacttttag aattagctcc tggtgaccca gcagatgcat atataaatcc tttaatgtct
    15121 tcacaggata ttgaaaatat aagggttaat atggggcttg ataaaccagt atatataaga
    15181 tatttaaact ggttgaaaaa cactttaagt ggaaacttag gtatttctta tataaaccat
    15241 atgcccgtta cagaacaaat tatggaaaaa atgggaaata catttattct tatgggtact
    15301 tctttgatat tttcaatatt ggtagctata cctcttggaa tacttttagc tgtaaataaa
    15361 aattcaataa ctagtaaagt atcatctgtt tttaattata taggtgtttc tataccttct
    15421 ttttggatag gtatgatact catttcaatt ttttcagtta aacttaacat tttcccatca
    15481 ggaggtatgc atactattgg aaatgatagt attggagatt tagtaaaaca tttagttttg
    15541 cctgtaataa ctttaggtct atataatact gctattttta caaattatgt agaagctagt
    15601 gtaaatgaac aattaaaaaa acaatatgtt attacagcaa gagcaaaagg attatcagaa
    15661 aaagtcatac tatttaaaca tgtcttgaaa aattcactga catcattggt tacaatccta
    15721 ggcatgagta tacaaaaatt agtcactggt gcatttgtta cagaagtagt tttctcttgg
    15781 ccaggtatgg gaagattaat gattgattca attttttcaa gagattatac tgtaattatg
    15841 gcaataacta tgttatcagc actattttta attttaggta atttagttgc tgatatacta
    15901 tacttattaa ttgaccctaa aataaaatct agcaaaggag gattctagtt gtgtttacaa
    15961 gtatcttaaa aaaattaaaa aaagataaat cctttgcttt tgcatgtatt actcttagca
    16021 taataatcat attaattata gcttctttta tattaaatat agactctaat gcaattgata
    16081 ctacttctaa acttcaagaa cctagcttaa agcatatctt tggtacagac gaacttggta
    16141 gagattactt ctctagagct ctttatggtg gaaggatttc acttagtgtt ggtattttat
    16201 caatgcttat ttctgtagta tttggtactg ctgtaggtgt tattagtgga tatattggag
    16261 gtaagctaga ccaattcttg atgagattag tggatatgct tatgagtata ccaagtttct
    16321 tagttttgat tgtattaaat acttatctaa cacctaaagt ttccactatt atactaatta
    16381 ttggattctt aagttggatg gaagtttcaa gaattgtacg tggcgaaaca ttaaaaataa
    16441 aggaaaatga atactgtcta gctgctaaag ctactggtat caaaactaga aatatactat
    16501 taagacatat agttttaaac ttaaaagaga ctattgtagt tgctggttcg ttaaatattg
    16561 ctaatgctat cttaactgaa tctgctctta gttttttagg tcttggaatc caattgcctc
    16621 ttgcatcatg gggtaatatg cttcaagatg ctcaaagaca tatttttgac aagttatatt
    16681 tagctgtatt tccaggatta cttatatttt taacagtcat gagtttgact ataataagca
    16741 aaaaattttc tagtaatact taacaaattt tatatagaaa ataaaaacag tgattatcta
    16801 aagatataca ctgtttttat ttttcgttta aaaaaataca tcttttgtat attataactt
    16861 taaatactac tctaccatgt tatgtaaagc ctattattgt tctcaaacat atagatgaaa
    16921 aactattagt ttattataat aaaaattgat ttatttgtta ttttaataac atttttaaga
    16981 gttcttttta ctaaagaaat ctataataaa tttaaataca tgttggtcta catggctata
    17041 acgttctttt ttaggtctac ataatataac tttccatgta ataggatgat taaaaggctt
    17101 ttctataatt ttgctatttt caaaaaaatc atgaactggt gatggtaaaa ttgttataaa
    17161 atcagaattt gtggttgata gcaacaaaaa atcccatgaa ccagacatta tatatctttt
    17221 taacttaaca ttttcatcag taaatttttg cattagctta tgatgtatca taaaagtagg
    17281 attaaatatt gcaagtaact gctcattcaa atcgttccaa tctatcttat ccttcttagc
    17341 aagtggatga tttatattta aaaatgctgt aagttcatct tcttgaagca catgttcagt
    17401 tactacactt ttatcaattt tatgtggatg taacaatact gcataatcta attcctgtaa
    17461 gataagcatt ctatttaagt catatgcacc cttctctact atatcaaatt ctatatctgg
    17521 attatttgca actaactgtg caactacatc tgaaaatgct attccaagta taagtggagg
    17581 tattcctatt ctaacttttc ctttaaattg aactgaatct tctcttaaat cttccatcat
    17641 atttttgtat tcatttatga tatgttctgc atttacataa aatctttctc ctgctggtgt
    17701 taacccattt aacctgcctt tatacctttc aaataaatat acatcttcac tttcttcaaa
    17761 attttttata atttgactta atgctggttg agatatgtga agtgtcttag atgctattga
    17821 taaattaaaa ccagatttca ctatttcaac aaaatatttc aactgtttta tatccatttt
    17881 aaaccccctt ccccaaaagt ataatttaga ttatattttt tcttctaatg atattttata
    17941 ggaaaatcaa cataatttca ttaatatttt aacaaaatat ttttctaaat ctactataaa
    18001 tttttatcct ataaattttt cttatacact atataaaaaa ttagacttag acaaaacgct
    18061 tttttcgccg taatctataa ttagaaacag gaaaacctaa agcattagga ataaaagtaa
    18121 ttgaaatact taaaaacaag cttgtattaa aaaagtactt tattatagtg ttccctaatt
    18181 tctttattca gaaaattttt aattatcatt caagaaaggt aactattaga tatgaaagat
    18241 gtagtaatcg tatcagcagt cagaacacct ataggaagtt ttggaggtgt atttaaaaat
    18301 acttcagctg ttcaacttgg aactatcgct gttaaagaag cgatatcacg tgtaagactt
    18361 aatttatctg aaatagatga agtaataatt ggaaatgttc ttcaaacagg gcttggacag
    18421 aatgttgcta gacaaattgc tataaatgca ggtataccaa attctgttcc aagctacaca
    18481 gtaaataaat tatgtggttc agggcttaaa agtgtccagc tagctgccca atcaatcaca
    18541 tctggtgaaa atgatgtggt aattgcaggt ggtactgaaa atatgagcca agctccttat
    18601 atcgttccaa ctgctcgctt tggtagtaaa atgggtgaca taaccatggt agatagtatg
    18661 ctaacagatg gccttattga tgctttcaat cagtatcata tgggaataac tgcagaaaat
    18721 attgcaacta aatttgaatt tactagagaa atgcaagata aattggcatt agaaagtcaa
    18781 aataaggctg agaatgctat aaaaaacaac cgctttaaag aagaaatcgt tccagtagat
    18841 gttttaatac gtcgaggaaa aatagaaact attgataaag atgaatatcc taaattaggt
    18901 atgacatttg aaggtttatc taaacttaaa cctgcattca aaaaagatgg tactgtaaca
    18961 gctggaaatg cctcaggtat taatgatggt gcggctatgt taatactaat gagccaacaa
    19021 aaagcagacg aactaggtat tagaccactt gctaaaataa aatcctatgc ttcagctggt
    19081 gttgaacctg aagtcatggg tactggtcca atccctgcaa ctagaaaagc actgaaaaaa
    19141 gctgggctta gcatcaatga tatagactta atagaagcaa acgaagcgtt tgctgcccaa
    19201 gcattagctg ttaaaaatga acttcaaata gattcatcaa agttaaatgt taatggtggt
    19261 gcaatagcat taggacatcc aataggagca agtggagcta gaatacttgt taccttaatt
    19321 tatgaaatgc aaaaacgtaa agttgaaact ggacttgcaa cactttgtat tggtggtggt
    19381 caaggaatat caatggtggt ttcacgatag gaggaaatat gaataaaata gttagcattg
    19441 atgaagctct atctcatgta aaagatggag atacaataat ggttggtgga ttcatggcca
    19501 atggttcacc agaaaattta attgattatt tatgtagtaa aaatataaaa gatttgacac
    19561 taatttgcaa tgatactggc tttattgaca aaggagttgg caaaatggtt gtaaataagc
    19621 aatttaaaaa gataattgct tctcatgtag gattaaataa agaaactgga agacaaatga
    19681 acaacaatga aacagatgtt gagttagttc ctcagggaac tcttgctgaa caaatacgtg
    19741 cagctggtta tggtctagga ggtatactca caccgactgg tattggtact cttgttgagg
    19801 agggaaagca aaaaattgtt gtcgatagca aagaatacct tcttgaaaaa ccaatttatg
    19861 cagatgttgc tcttctattt gcatcaaagg tcgataaagc aggtaatcta gtttataaag
    19921 gctctatgaa caattttaat aatttaatgg catctgctgc caaaattaca atagttgaag
    19981 cagatgaaat cgttgaaatt ggtgatattg acccaaatga agttaataca ccaggtattt
    20041 ttgtgaatta catcgttgaa ggaggtaatt tataatggat aaattagaaa tgcaagaata
    20101 tattgcaaat agagtatcta aagaattaaa agacggagcc gttgtaaacc ttggaatagg
    20161 tctaccaacc aaagtagcaa attatattcc ggataatgta aacgttatct tacaatctga
    20221 aaatggcttt ttaggtttag gttcagccga agatggaaat tcaagtgatg aaactattgt
    20281 aaatgcaggt ggtcaaccag ttactatact tcctggagga tgtttctttg atagtgctac
    20341 ttcttttgga ataatcagag gaggtcatgt tgatataact gttcttggcg cacttcaggt
    20401 tgacaaatat ggcaatatag caaactatat gattccaggt aagatggttc caggtatggg
    20461 tggagctatg gacctagtaa ctggagctaa aaaagttatt gtagcaatgg aacatacttc
    20521 aaaaggttct gcaaaaatat taaataattg tactcttcca cttactgcaa caaatgctgt
    20581 agatttgata gttactgaaa tgggagttat ggaagtaaca tcagatggaa ttttacttaa
    20641 agaaataaat ccagctttca cattagatga tgttatttct gctactgagg ctcctttaat
    20701 attgtcagat tcattaaatg gaaaaatatc tgttgtttaa aataattaaa actagaaaat
    20761 aaaaatctct tagacgtatt acatataaat ttgtattgct taaaatatta atataaaaat
    20821 aaaataaaat tggaggaaat gaaaatggtt aaagataaag ttgtattcgt aacaggagct
    20881 gcaagtggaa taggtaaaca aatagctgaa tcgttcttaa aaaatggtgc taaagtaatg
    20941 ttctctgata taaatcaaga agctttaaat aataccataa cagagttaca aaaaaaaggt
    21001 tatgattgca tgagtgtaaa gtgtgatgta actaaggaag aagaaattaa ccacgctata
    21061 gacaaaactg ttgaaaagta tggcagatta gatatattaa taaacaatgc tggacttcaa
    21121 catgtttcta tgatagaaga tttcccaact gataaatttg aatttatgat aaaaataatg
    21181 ctgacagcac cttttatagc tactaaaaaa gcatttccta taatgaaaaa acaaggcttt
    21241 ggtcgtataa taaatatggc ctcaatcaat ggtgtaatag gatttgctgg aaaggctgct
    21301 tataactcag caaaacatgg acttattgga ctaacaaaag ttgctgctct tgaagctgcc
    21361 gattctggta taacagttaa tgctttatgc cctggatatg tagatactcc acttgtcaga
    21421 ggtcagttca atgacctttc aaaaactcgt aatataccat tggaaaatgt cttagaggaa
    21481 gttttatacc cacttgtacc acaaaaacgc ctattagatg ttcaagaaat tgccgactat
    21541 gctatgttct tagcaagtga taatgctaag ggtattacag gacaagcttg cttactagat
    21601 ggaggatata ctgcacaata gttattatat ttagggcttg aagaaagtat tcttcaggtc
    21661 cttctactaa ggagggatat ttatgagtat tatcgcgcca attggtataa ttattggtat
    21721 catagctatt atatattttt cagttaaaga aattcatata actatagctg ctccaatagc
    21781 aactttaata gttgttattt taaataaaat ggatgttgta acgtcaatgc taggtgctga
    21841 caaaaacaat tatatgggtg cacttggaaa ctatataatg agttattttg caatattctt
    21901 attaggctca atacttgcta aatttatgga agaaagtgga gctactgtat caatagctga
    21961 ttttatttta aataaatttg gctctaatca tccttataga gttttagttg ctatatttat
    22021 agtaagtttt atattaacgt atggtggtat aagcttattt gtagttatgt ttgcggtcat
    22081 tccacttgca agaactctat ttaaaaaact tgatatttct tggaacctta ttcagatacc
    22141 actttggctt ggtattgcaa caattactat gactataatt cctggaacac cagccattca
    22201 aaatgttata cctattcaat atctaaatac gtctcttact gcagctacta taccaagtat
    22261 tgtaggtagt ataggttgtg ctacgtttgg acttgtctat atgaaatatg ctctaaacaa
    22321 aagtattaga aaaggtgaaa cttatgcaac ttatacttca gaattagaag aagaatcttt
    22381 agatagagaa ttaccaggat tttttgcaag tatttttcct ctattagcac tcgtaattat
    22441 agctataact ggaagtactt ttggttcaga atttatgaaa aaaaatgtaa tttacatagc
    22501 tttaatagtt gcaattcttt tatctgcttt tttattccat aaatttctat catctaagat
    22561 acagacattg agcataggtg ctagtggttc tataggtcct atatttgcta catcttctgc
    22621 agttgcattt ggagcagtaa taatggctgc acctggtttt gatgtattta gcaaacttat
    22681 aatgtcaata ccaggtagtc cacttataag tcttactgtt ttgacttcaa caatgtcagc
    22741 aataacaggg tcctcttctg gtgcattagg aatagtaatg ccaaactttg cagattatta
    22801 tttaagtact ggtctaaatc cagaattaat tcaccgtgtt gctacaatag cttcaaatat
    22861 actaactata gttccacaaa gtggtgtttt tcttacattc ttaagcttat ctaagttaac
    22921 acataaaact ggatttaaag aaactttcat tgtagttgca gttggttcac taatagcaga
    22981 aattattgta attacattag gattactaat gtattaatat aaaacaaatt aaaattcata
    23041 atatgaaagg tggtgtctca aagtgaactt tttacttaat gagacactct ttttatatga
    23101 aataacatat gcctatcatt taaacaataa aaaagaacct tatctctatt ttgagacaga
    23161 ccctttttat ttcttaaaga tttaaataat tataatttgt tgctaatacg aaagcatcta
    23221 ctgaataaat ttaaccaaat aaaaaaaaat ttatcataac tataaattta cgttatggaa
    23281 ttattataaa aatattattt tctctaacta agtaattcca tactatacag gcttttaata
    23341 caaattgtca aacacactga aatataccta tttattccat atatatcttt tttacatatc
    23401 tttacagtaa aaaaagtctt aatcttatgt tagtatagat tcacgggtaa ccccctacac
    23461 taaaggttac aaatcagtaa catttttaga atttttagat taagaggtgt ttaatgatga
    23521 gaagaaatat accaacaaaa ttaaaaacta tattagcttt aggagtgtta actttagcaa
    23581 cagcttcaag tgctgttact gcaagtgctt catcacttga aaataatgta aatataagta
    23641 acaaaagttt agtatatagt aatactaaat acaagttttc tgcaaaacca aattgttctg
    23701 taaaaccaga acttaagcct gataaagata actcttgtaa ggataagaat cataatgaca
    23761 agaattgcaa caacactaat aaacctgagg acaacaataa ttcagactct actaataagc
    23821 ctgataacaa taaacctgag tctaataaac ctgaagacaa caataattca ggctctacta
    23881 ataaacctga taacaataaa cctgagtcta ataaacctga agacaacaat aattcaggct
    23941 ctactgataa acctgataac aataaacctg agtctaataa acctgaagac aacaataatt
    24001 cagactctac taacaaacct gatgataata acaactcagg ctctacaagt gaaagttttt
    24061 cagcttacca aaaagaagtt gttgacttag taaatataga aagagctaaa gctggattaa
    24121 atcctcttac tcttgattct tctatatcaa atgttgctac aaaaaaatct caagatatga
    24181 ttgataacaa ctatttttca cacaattctc caacttatgg ttctccattt gacatgttga
    24241 aaaaatttgg aataagctat aagacagcag gtgaaaatat agctatgggt caaaaaactc
    24301 ctaaagaagt tgtaaacgca tggatgaatt ctgaaggtca cagaaaaaat ataatgaatc
    24361 caaatttcag taaaataggt gttggagtag cacaaaaaag tggtggttca atttattgga
    24421 cacaaatctt tgtaggataa aatactcttt ttccatacat atcaagagag tatctctaag
    24481 tgataaaaaa cacaaatgag atactctttt gtatctattt taaaattatc aaatccaaat
    24541 atacatacta taaatattat ttgttctctt aattttagtg tgtaaaacaa tatataaaaa
    24601 gtattggcaa gatgaaaatg gaaaacttaa aaaagatatt taataggtaa aaacaaaatc
    24661 ttaatatctt cataaaaaaa ggctgtctca aaatagagat aaggcctttt tcattgttga
    24721 aatgattaaa atatatttga tttcatacaa aaagagtgcc tcatgaacta aaaagctcac
    24781 tttgagacac tctcttttat caattctata taagcattat aatactttaa tattattcag
    24841 ctaatttttt gtatccttca tatctttctt tagcatcagc ttcagcttta gcaaataatc
    24901 catcagcttc ctctgggaat tgtttagcta tagcagaata tcttacttgt gcaagtatga
    24961 aatctttgaa gcttgcagtt ggttcttttg aatctaaagt gaatgggttt ttaccttcag
    25021 cttttacttc tggattgaat ctgtataaat gccagtatcc gcaagcaaca gcttgtgctt
    25081 cgttagctac agttcttccc ataccttctt ttaatccatg gtttatacat ggagcataag
    25141 ctattattaa agatggccca tcatgttttt cagcttctat aacggctttg ataaattggt
    25201 ttttatcagc acccatagca acttgagcta catatacgtt tccatatgtc atagccatca
    25261 ttcctaaatc tttctttcta gattttttac ctgaagcagc aaacttagcc atagcagcag
    25321 ctggagtagc tttagaagct tgacctcctg tatttgaata tacttctgta tcaaatacaa
    25381 gtacatttac atcttcacca gatgcaagaa catggtctaa tccaccgtaa ccgatatcat
    25441 atgcccaacc gtctccacct agtatccatt gagatctctt aactagataa tcttttctat
    25501 cttttatagc ttttactaat tctttagctt tttcatctgt acaatcacaa gctggttttt
    25561 ctaataattc aacaacctta gcacttgcta ctttagaagc ttctccatca tttctagaat
    25621 ctaaccactc tgtaaatact gctttagcat cttcacagat atccatagaa actaactctg
    25681 tcatagcatc tactatttta tttcttattt gcttaacagc tgtgtacata ccaaatccat
    25741 attcagcatt atcctcgaat aaagaatttg cccaagatgg acctttacct tcatggttac
    25801 aagtataagg aattgatggt gcagaagctc cccatataga agaacatcca gtagcattag
    25861 ctatcatcat tctatctcca tataattgtg taactacttt aatgtatgca gtttctccac
    25921 atccagcaca tgctcctgaa aactccatta atggttgtct aaattggctt cctttaacag
    25981 tgtttgcagg cataacatca ccttttggag ctacctcatc aggatttact gcaaatgccc
    26041 aattatctaa ctctgtatca agttgagtat ctattggctt cataactaaa gctttttctt
    26101 tagctggaca tatgtcagca cagtttccac atcctgtaca gtcaagtggg ctaagttgca
    26161 ttctatattt taatccttct aatcctttac ctaatgcttt tttagcttca aatccttctg
    26221 gagcattagc taattcttct tcagtaacta atactggtct tatacatgaa tgaggacata
    26281 taaaagaaca ttggttacat tgaatacagt tatctattat ccattcagga acatcaacag
    26341 ctataccacg tttttcataa gctgcagtac cacaagggaa tgttccatct tctataccat
    26401 tgaatgtact tactggtaag ttgtttcctt cttgtgcagt cattggtctt agtatatttt
    26461 ttataaattc tggttcttta acttctcctt tatctgcatc aacagcattt tcccaagaag
    26521 ctggaacttc aactttaact aaagcattta ttcctgcatc aacagcagca tagttcatgt
    26581 taactatttt ttcacctttt ttaccataag ctttaactat agaatctttt aagtatttaa
    26641 cagcatcttc ttctggtatt atttcagcta atttaaagaa tgcagattgc attatcatat
    26701 ttattctgtt tccaagacct atttcttgtc ctagtttaac agcgttaact gtatagaatt
    26761 ttatatcatt tttagctata tattgcttca tatgagctgg taaatgttct tcaagtcctg
    26821 cttggtccca tatagtgtta agcacaaatg taccaccttt tttaagacct tttaataaat
    26881 catattgata aacatatgat tgtttatgac aggcaatata atcagcttca tctattaaat
    26941 aagtagctct tattggagta tcaccaaatc ttaagtgaga catagttata ccaccagatt
    27001 ttttagagtc ataatcaaag taagcttgag catatttttc agtatggtca ccgattattt
    27061 tgatagcttg tttattagct ccaacagtac cgtcagaacc taatccccag aacttacatc
    27121 ttatagttcc tttagaagct atttttattg gctcagatgg agttaaagaa gtattagtta
    27181 catcatcaac tatacctact gtaaatccat ttttaggttg ttctgaaact aagttatcaa
    27241 aaacagtttt tatatctgaa ggagtagtat cttttgaacc taatccgtat cttccaccta
    27301 ttatcatagg agcattttct tttccataga atacatcacg tacatctaag tataatggtt
    27361 caccagttga acctggctct ttagttctat caagtacaca tattctttca acagtagatg
    27421 gcatagcatc taagaaatgt ttcattgaga atggtctata taaatgaact ttaactaaac
    27481 catatttttc tcccttagca tttaagtaat ctatagtttc ttctatagtt tctgttactg
    27541 aacccatagc tattaataca tatttagcat cttctgctcc atagtaatca aataaactat
    27601 gttttctacc tgttaaatta ctcatttttt ccatgtattt ttcaactata cctactatat
    27661 tttgatagta tttattagaa gcttctctag tttggaaata tatatctggg ttttgagcag
    27721 taccacgagc aactggatga tttggagata aagcattatc tctaaatgct tgaactgctt
    27781 caaagtttaa taaacttgca taatcttcat tttctagtaa ttcaactttt tggatttcat
    27841 gtgaagttct gaatccatca aagaaatgta taaatggtaa tctaccttct attgcagcta
    27901 aatgtgcaac aggtgctata tcagctactt cttgaactga accagaagct aataatacac
    27961 atccagtttg tctagcagcc ataacgtctt ggtgatcccc aaatattgat aacgcttgag
    28021 atgctaaagc acgagcactt acatggaata ctcctggtaa caactctcct gcaactttat
    28081 acatgttagg tatcattaat aataaacctt gagatgctgt aaaagtagaa gttaaagctc
    28141 ctccttgtaa agaaccgtgg aatgttcctg atgcacctgc ttctgactgc atttcaacaa
    28201 cattaactgt ttgtccaaat atattttttc ttccttgtga tgcccactca tcaactactt
    28261 cagccatagt tgaagatggt gtgattggat atatagctgc tacatctgta aacgcatagg
    28321 caacatgagc tgcagctgta tttccatcaa gtgttttcat aaacttagcc ataatatgta
    28381 tcctccttga tagctacaat tgtacttgtt tataacaagt ctattttttt atatttacat
    28441 ataatttaca caacaaaaat ataaacacac atatagtcgc gcaaatactc tatcttctaa
    28501 tataatacta cagattagat aaaattcctt tgaaaattgt aaattaatta catatttaag
    28561 tagatttttt ttaaaattaa atatgttaag tttt
//
LOCUS       DAMJXI010000045        28019 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.047, whole genome shotgun sequence.
ACCESSION   DAMJXI010000045 DAMJXI010000000
VERSION     DAMJXI010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28019
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.047"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            116..670
                     /gene="tcdR"
                     /locus_tag="PC465_002528"
     CDS             116..670
                     /gene="tcdR"
                     /locus_tag="PC465_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin sigma factor TcdR"
                     /protein_id="HDF2649814.1"
                     /translation="MQKSFYELIVLARNNSVDDLQEILFMFKPLVKKLSRVLHYEEGE
                     TDLIIFFIELIKNIKLSSFSEKSDAIIVKYIHKSLLNKTFELSRRYSKMKFNFVEFDE
                     NILNMKNNYQSKSVFEEDICFFEYILKELSGIQRKVIFYKYLKGYSDREISVKLKISR
                     QAVNKAKNRAFKKIKKDYENYFNL"
     gene            988..8088
                     /gene="tcdB"
                     /locus_tag="PC465_002529"
                     /gene_synonym="toxB"
     CDS             988..8088
                     /gene="tcdB"
                     /locus_tag="PC465_002529"
                     /gene_synonym="toxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_074049122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdB"
                     /protein_id="HDF2649815.1"
                     /translation="MSLVNRKQLEKMANVRFRTQEDEYVAILDALEEYHNMSENTVVE
                     KYLKLKDINSLTDIYIDTYKKSGRNKALKKFKEYLVTEVLELKNNNLTPVEKNLHFVW
                     IGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTVVESAINDTLESFREN
                     LNDPRFDYNKFFRKRMEIIYDKQKNFINYYKAQREENPELIIDDIVKTYLSNEYSKEI
                     DELNTYIEESLNKITQNSGNDVRNFEEFKNGESFNLYEQELVERWNLAAASDILRISA
                     LKEIGGMYLDVDMLPGIQPDLFESIEKPSSVTVDFWEMTKLEAIMKYKEYIPEYTSEH
                     FDMLDEEVQSSFESVLASKSDKSEIFSSLGDMEASPLEVKIAFNSKGIINQGLISVKD
                     SYCSNLIVKQIENRYKILNNSLNPAISEDNDFNTTTNTFIDSIMAEANADNGRFMMEL
                     GKYLRVGFFPDVKTTINLSGPEAYAAAYQDLLMFKEGSMNIHLIEADLRNFEISKTNI
                     SQSTEQEMASLWSFDDARAKAQFEEYKRNYFEGSLGEDDNLDFSQNIVVDKEYLLEKI
                     SSLARSSERGYIHYIVQLQGDKISYEAACNLFAKTPYDSVLFQKNIEDSEIAYYYNPG
                     DGEIQEIDKYKIPSIISDRPKIKLTFIGHGKDEFNTDIFAGFDVDSLSTEIEAAIDLA
                     KEDISPKSIEINLLGCNMFSYSINVEETYPGKLLLKVKDKISELMPSISQDSIIVSAN
                     QYEVRINSEGRRELLDHSGEWINKEESIIKDISSKEYISFNPKENKITVKSKNLPELS
                     TLLQEIRNNSNSSDIELEEKVMLTECEINVISNIDTQIVEERIEEAKNLTSDSINYIK
                     DEFKLIESISDALCDLKQQNELEDSHFISFEDISETDEGFSIRFINKETGESIFVETE
                     KTIFSEYANHITEEISKIKGTIFDTVNGKLVKKVNLDTTHEVNTLNAAFFIQSLIEYN
                     SSKESLSNLSVAMKVQVYAQLFSTGLNTITDAAKVVELVSTALDETIDLLPTLSEGLP
                     IIATIIDGVSLGAAIKELSETSDPLLRQEIEAKIGIMAVNLTTATTAIITSSLGVASG
                     FSILLVPLAGISAGIPSLVNNELVLRDKATKVVDYFKHVSLVETEGVFTLLDDKIMMP
                     QDDLVISEIDFNNNSIVLGKCEIWRMEGGSGHTVTDDIDHFFSAPSITYREPHLSIYD
                     VLEVQKEELDLSKDLMVLPNAPNRVFAWETGWTPGLRSLENDGTKLLDRIRDNYEGEF
                     YWRYFAFIADALITTLKPRYEDTNIRINLDSNTRSFIVPIITTEYIREKLSYSFYGSG
                     GTYALSLSQYNMGINIELSESDVWIIDVDNVVRDVTIESDKIKKGDLIEGILSTLSIE
                     ENKIILNSHEINFSGEVNGSNGFVSLTFSILEGINAIIEVDLLSKSYKLLISGELKIL
                     MLNSNHIQQKIDYIGFNSELQKNIPYSFVDSEGKENGFINGSTKEGLFVSELPDVVLI
                     SKVYMDDSKPSFGYYSNNLKDVKVITKDNVNILTGYYLKDDIKISLSLTLQDEKTIKL
                     NSVHLDESGVAEILKFMNRKGNTNTSDSLMSFLESMNIKSIFVNFLQSNIKFILDANF
                     IISGTTSIGQFEFICDENDNIQPYFIKFNTLETNYTLYVGNRQNMIVEPNYDLDDSGD
                     ISSTVINFSQKYLYGIDSCVNKVVISPNIYTDEINITPVYETNNTYPEVIVLDANYIN
                     EKINVNINDLSIRYVWSNDGNDFILMSTSEENKVSQVKIRFVNVFKDKTLANKLSFNF
                     SDKQDVPVSEIILSFTPSYYEDGLIGYDLGLVSLYNEKFYINNFGMMVSGLIYINDSL
                     YYFKPPVNNLITGFVTVGDDKYYFNPINGGAASIGETIIDDKNYYFNQSGVLQTGVFS
                     TEDGFKYFAPANTLDENLEGEAIDFTGKLIIDENIYYFDDNYRGAVEWKELDGEMHYF
                     SPETGKAFKGLNQIGDYKYYFNSDGVMQKGFVSINDNKHYFDDSGVMKVGYTEIDGKH
                     FYFAENGEMQIGVFNTEDGFKYFAHHNEDLGNEEGEEISYSGILNFNNKIYYFDDSFT
                     AVVGWKDLEDGSKYYFDEDTAEAYIGLSLINDGQYYFNDDGIMQVGFVTINDKVFYFS
                     DSGIIESGVQNIDDNYFYIDDNGIVQIGVFDTSDGYKYFAPANTVNDNIYGQAVEYSG
                     LVRVGEDVYYFGETYTIETGWIYDMENESDKYYFNPETKKACKGINLIDDIKYYFDEK
                     GIMRTGLISFENNNYYFNENGEMQFGYINIEDKMFYFGEDGVMQIGVFNTPDGFKYFA
                     HQNTLDENFEGESINYTGWLDLDEKRYYFTDEYIAATGSVIIDGEEYYFDPDTAQLVI
                     SE"
     gene            8210..8710
                     /gene="tcdE"
                     /locus_tag="PC465_002530"
     CDS             8210..8710
                     /gene="tcdE"
                     /locus_tag="PC465_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin-like glycosylating toxin export protein
                     TcdE"
                     /protein_id="HDF2649816.1"
                     /translation="MHSSSPFYISNGNKIFFYINLGGVMNMTISFLSEHIFIKLVILT
                     ISFDTLLGCLSAIKSRKFNSSFGIDGGIRKVAMIACIFFLSVVDILTKFNFLFMLPQD
                     CINFLRLKHLGISEFFSILFILYESVSILKNMCLCGLPVPKRLKEKIAILLDAMTDEM
                     NAKDEK"
     gene            9039..9221
                     /locus_tag="PC465_002531"
     CDS             9039..9221
                     /locus_tag="PC465_002531"
                     /inference="COORDINATES: protein motif:HMM:NF022413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649817.1"
                     /translation="MRDEGQNDIENKYQTLINDLIDSLKVIGKIYKEIKTLKKYKICL
                     QITIRQSPYLIEESIN"
     gene            9438..17570
                     /gene="tcdA"
                     /locus_tag="PC465_002532"
                     /gene_synonym="toxA"
     CDS             9438..17570
                     /gene="tcdA"
                     /locus_tag="PC465_002532"
                     /gene_synonym="toxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_105161403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdA"
                     /protein_id="HDF2649818.1"
                     /translation="MSLISKEELIKLAYSIRPRENEYKTILTNLDEYNKLTTNNNENK
                     YLQLKKLNESIDVFMNKYKTSSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWI
                     GGEVSDIALEYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEI
                     QNPQFDNMKFYKKRMEFIYDRQKRFINYYKSQINKPTVPTIDDIIKSHLVSEYNRDET
                     VLESYRTNSLRKINSNHGIDIRANSLFTEQELLNIYSQELLNRGNLAAASDIVRLLAL
                     KNFGGVYLDVDMLPGIHSDLFKTISRPSSIGLDRWEMIKLEAIMKYKKYINNYTSENF
                     DKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAFALGSVINQALISKQGS
                     YLTNLVIEQVKNRYQFLNQHLNPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIA
                     PYLQVGFMPEARSTISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLS
                     QLTEQEINSLWSFDQASAKYQFEKYVRDYTGGSLSEDNGVDFNKNTALDKNYLLNNKI
                     PSNNVEEAGSKNYVHYIIQLQGDDISYEATCNLFSKNPKNSIIIQRNMNESAKSYFLS
                     DDGESILELNKYRIPERLKNKEKVKVTFIGHGKDEFNTSEFARLSVDSLSNEISSFLD
                     TIKLDISPKNVEVNLLGCNMFSYDFNVEETYPGKLLLSIMDKITSTLPDVNKNSITIG
                     ANQYEVRINSEGRKELLAHSGKWINKEEAIMSDLSSKEYIFFDSIDNKLKAKSKNIPG
                     LASISEDIKTLLLDASVSPDTKFILNNLKLNIESSIGDYIYYEKLEPVKNIIHNSIDD
                     LIDEFNLLENVSDELYELKKLNNLDEKYLISFEDISKNNSTYSVRFINKSNGESVYVE
                     TEKEIFSKYSEHITKEISTIKNSIITDVNGNLLDNIQLDHTSQVNTLNAAFFIQSLID
                     YSSNKDVLNDLSTSVKVQLYAQLFSTGLNTIYDSIQLVNLISNAVNDTINVLPTITEG
                     IPIVSTILDGINLGAAIKELLDEHDPLLKKELEAKVGVLAINMSLSIAATVASIVGIG
                     AEVTIFLLPIAGISAGIPSLVNNELILHDKATSVVNYFNHLSESKKYGPLKTEDDKIL
                     VPIDDLVISEIDFNNNSIKLGTCNILAMEGGSGHTVTGNIDHFFSSPSISSHIPSLSI
                     YSAIGIETENLDFSKKIMMLPNAPSRVFWWETGAVPGLRSLENDGTRLLDSIRDLYPG
                     KFYWRFYAFFDYAITTLKPVYEDTNIKIKLDKDTRNFIMPTITTNEIRNKLSYSFDGA
                     GGTYSLLLSSYPISTNINLSKDDLWIFNIDNEVREISIENGTIKKGKLIKDVLSKIDI
                     NKNKLIIGNQTIDFSGDIDNKDRYIFLTCELDDKISLIIEINLVAKSYSLLLSGDKNY
                     LISNLSNTIEKINTLGLDSKNIAYNYTDESNNKYFGAISKTSQKSIIHYKKDSKNILE
                     FYNDSTLEFNSKDFIAEDINVFMKDDINTITGKYYVDNNTDKSIDFSISLVSKNQVKV
                     NGLYLNESVYSSYLDFVKNSDGHHNTSNFMNLFLDNISFWKLFGFENINFVIDKYFTL
                     VGKTNLGYVEFICDNNKNIDIYFGEWKTSSSKSTIFSGNGRNVVVEPIYNPDTGEDIS
                     TSLDFSYEPLYGIDRYINKVLIAPDLYTSLININTNYYSNEYYPEIIVLNPNTFHKKV
                     NINLDSSSFEYKWSTEGSDFILVRYLEESNKKILQKIRIKGILSNTQSFNKMSIDFKD
                     IKKLSLGYIMSNFKSFNSENELDRDHLGFKIIDNKTYYYDEDSKLVKGLININNSLFY
                     FDPIEFNLVTGWQTINGKKYYFDINTGAALTSYKIINGKHFYFNNDGVMQLGVFKGPD
                     GFEYFAPANTQNNNIEGQAIVYQSKFLTLNGKKYYFDNDSKAVTGWRIINNEKYYFNP
                     NNAIAAVGLQVIDNNKYYFNPDTAIISKGWQTVNGSRYYFDTDTAIAFNGYKTIDGKH
                     FYFDSDCVVKIGVFSTSNGFEYFAPANTYNNNIEGQAIVYQSKFLTLNGKKYYFDNNS
                     KAVTGWQTIDSKKYYFNTNTAEAATGWQTIDGKKYYFNTNTAEAATGWQTIDGKKYYF
                     NTNTAIASTGYTIINGKHFYFNTDGIMQIGVFKGPNGFEYFAPANTDANNIEGQAILY
                     QNEFLTLNGKKYYFGSDSKAVTGWRIINNKKYYFNPNNAIAAIHLCTINNDKYYFSYD
                     GILQNGYITIERNNFYFDANNESKMVTGVFKGPNGFEYFAPANTHNNNIEGQAIVYQN
                     KFLTLNGKKYYFDNDSKAVTGWQTIDGKKYYFNLNTAEAATGWQTIDGKKYYFNLNTA
                     EAATGWQTIDGKKYYFNTNTFIASTGYTSINGKHFYFNTDGIMQIGVFKGPNGFEYFA
                     PANTHNNNIEGQAILYQNKFLTLNGKKYYFGSDSKAVTGLRTIDGKKYYFNTNTAVAV
                     TGWQTINGKKYYFNTNTSIASTGYTIISGKHFYFNTDGIMQIGVFKGPDGFEYFAPAN
                     TDANNIEGQAIRYQNRFLYLHDNIYYFGNNSKAATGWVTIDGNRYYFEPNTAMGANGY
                     KTIDNKNFYFRNGLPQIGVFKGSNGFEYFAPANTDANNIEGQAIRYQNRFLHLLGKIY
                     YFGNNSKAVTGWQTINGKVYYFMPDTAMAAAGGLFEIDGVIYFFGVDGVKAPGIYG"
     gene            complement(17905..18603)
                     /gene="tcdC"
                     /locus_tag="PC465_002533"
     CDS             complement(17905..18603)
                     /gene="tcdC"
                     /locus_tag="PC465_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin anti-sigma factor TcdC"
                     /protein_id="HDF2649819.1"
                     /translation="MFSKKNEGNEFSNEGKGSSKKIIKFFKSTKGIALLAFILGVFFG
                     NISSPSCSEDHEEVISNQTSVIDSQKTEIETLNSKLSDAEPWFKMKDDEKKAIEAENQ
                     RKAEEAKKAEEAKKAEEQRKKEEEEKKGYDTGITYDQLARTPDDYKYKKVKFEGKVIQ
                     VIEDGDEVQIRLAVSGNYDKVVLCSYKKSITPSRVLEDDYITIRGISAGTITYESTMG
                     GNITIPGIAVEKIN"
     gene            19029..19274
                     /locus_tag="PC465_002534"
     CDS             19029..19274
                     /locus_tag="PC465_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pathogenicity locus"
                     /protein_id="HDF2649820.1"
                     /translation="MGELQKIPGVGKATEKSLIMLGYTTIKSLKDANPAQMYEKECLM
                     RGQHIDRCQLYVYRCAVYFASTENPEPEKLKWWYWKD"
     gene            complement(19492..19761)
                     /locus_tag="PC465_002535"
     CDS             complement(19492..19761)
                     /locus_tag="PC465_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HDF2649821.1"
                     /translation="MFESRCGVCCDSCTKKEQVNCTGCPTMEKPFWGGECKVKTCCES
                     KELNHCGECDTFPCDMLLNKGKDQGFDPMVNIEQCRKWLEETVSN"
     gene            complement(20639..21376)
                     /locus_tag="PC465_002536"
     CDS             complement(20639..21376)
                     /locus_tag="PC465_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2649822.1"
                     /translation="MLRKSVLGEILKLKNSFIWYVLLALPLISVLIGSGNFYLNQGIL
                     KKEWYSLWTQVSLFYGEFFFPILIAIFCAYICRLEHMNHNWNNVMTLPVNLKNIFLSK
                     LTVVSILTAITQVFFVIFYIVAGNMFGFSGSVPKELTGWIAKGWIISISIASIQLYMS
                     IKIRSFATPIGISLCLSLFGMGLIVAKPAVGIFFPYSMLGSAMGVIKQSALNVNDTIV
                     TICVAFITTIVFSEIANRNFRKNDVIS"
     gene            complement(21388..22149)
                     /locus_tag="PC465_002537"
     CDS             complement(21388..22149)
                     /locus_tag="PC465_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2649823.1"
                     /translation="MKYLGLEFYKLKRKKIILMTFLFAAVEIMWCIVNSNRAITRNPD
                     MLGGFEYSYMLMSFASLNGLFFPILISIITSRISDIEHKGDTWKLLKSSVTSLNSIYL
                     SKFLCSAILVSIPVLMQVLSIVLFGHFRGVIESISVSLLLKYTLGTILVSIAIIALHL
                     WIATVIPNQMIAITFGMIGSFIGLTSGLFYQGIRRLFIWSYYLELSPLSYAYDNVLGS
                     SVYRIDMNFSITILVFLIGMLIYYIGRNHLLKKEV"
     gene            complement(22149..23063)
                     /locus_tag="PC465_002538"
     CDS             complement(22149..23063)
                     /locus_tag="PC465_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2649824.1"
                     /translation="MEMIIRTQRLSKEYNKIFRVKDIDLRVPQGAVYGFLGPNGAGKS
                     TTLKMLLGLAKPTQGNINILGKELNEKNRISILKDIGSLIESPSYYGHLTGLENMTIM
                     QRLLDLPKKNVNEALKIVRLENQKNKKVSQYSLGMKQRLGIAMAIMKFPKLLILDEPT
                     NGLDPAGIEEIRELIKSLPEKYGMTVLISSHLLSEIDQIATSIGIINHGELVFQDSIK
                     ELHNRGQSQIAIKTKNVVSAQKLLNTKGYMSLIQDGYLTIENLKDSDVAKINGMLVHS
                     NIDVFRIEEHKKSLEDIFLELTGKAVTL"
     gene            23234..23941
                     /locus_tag="PC465_002539"
     CDS             23234..23941
                     /locus_tag="PC465_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2649825.1"
                     /translation="MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAV
                     KVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIPVIFLSARGEDEDRLIGLGLGAD
                     DYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKEGQEIS
                     LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPST
                     PKHLITVRGLGYKLMIN"
     gene            23986..25392
                     /locus_tag="PC465_002540"
     CDS             23986..25392
                     /locus_tag="PC465_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2649826.1"
                     /translation="MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSD
                     NLDTSDSREIKSNLIMIEDNLVLKDGKFILDDSSKEILHKNKVWAMLIDNNGDRIWGF
                     DLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTVKE
                     IEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGIL
                     SDISKSINTVSKELQMKDEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSS
                     LSNREQEQVSIICNQGIKIRELVNDLNLVSKLEYNMQALNCDKIRVSAFLRELISEFI
                     NNNLDNDFYVELDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLD
                     FCYIIVEDDGKGMSQERINSLLKSQNGLSEAYAKGQNHGLGILIVSGIINAHRGKLDI
                     TSIDSQGLKTILKLPLIK"
     gene            27152..27541
                     /locus_tag="PC465_002541"
     CDS             27152..27541
                     /locus_tag="PC465_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2649827.1"
                     /translation="MTIKKLPQSELKIMKFIWKSDSKVTSRDIVLGMEQKYQWKQTTT
                     LTLLSRLVVKRFLNSQKIDKYTHYEVLIKEKEYIGVETRDFFRNIHDSSIKSLLLSLH
                     ENINLSKDDILLIEEWIKNLKEEEKDV"
BASE COUNT        11059 a         3107 c         4306 g         9547 t
ORIGIN      
        1 ttcatataaa atttaattta tttgccgatt atataattat aatgactgat ttaattccga
       61 tgttgtcaaa attttcaaat aaatcatcat tataaatata agagaggatg attttatgca
      121 aaagtctttt tatgaattaa ttgttttagc aagaaataac tcagtagatg atttgcaaga
      181 aattttattt atgtttaagc cattagtaaa aaaacttagt agagttttac attatgaaga
      241 gggagaaaca gatttaataa tattttttat tgaattaata aaaaatatta aattaagtag
      301 cttttcagaa aaaagcgatg ctattatagt caaatatatt cataaatcat tactgaataa
      361 gacttttgag ttgtctagaa gatattctaa aatgaagttt aattttgtag aatttgatga
      421 aaatatctta aatatgaaaa ataattatca aagtaagtct gtttttgagg aagatatttg
      481 ttttttcgaa tatattttga aagaattatc tggtattcaa agaaaagtta ttttttataa
      541 atatttaaaa ggatattctg atagagaaat atcagtgaaa ttaaaaatat ctagacaagc
      601 tgttaataag gctaaaaata gagcatttaa aaaaataaaa aaagactatg aaaattattt
      661 taacttgtaa ttaatgagct taaagaaata tttacaatag aaatcaaatt ttagaattaa
      721 ctttattgta aaatcaataa cttaatctaa gaatatctta atttttatat tttatataga
      781 acaaagttta catatttatt tcagacaacg tctttattca atcgaagagc aaattaatca
      841 actgagtgtc ttaaatttaa aatgttagga agtgaatgta tatgaaaacc taagtagata
      901 ttagtatatt ttataaatag aaaggaggat atataaaaga gttttagcat ttagatgtaa
      961 aaatattata gtaaaggaga aaattttatg agtttagtta atagaaaaca gttagaaaaa
     1021 atggcaaatg taagatttcg tactcaagaa gatgaatatg ttgcaatatt ggatgcttta
     1081 gaagaatatc ataatatgtc agagaatact gtagtcgaaa aatatttaaa attaaaagat
     1141 ataaatagtt taacagatat ttatatagat acatataaaa aatctggtag aaataaagcc
     1201 ttaaaaaaat ttaaggaata tctagttaca gaagtattag agctaaagaa taataattta
     1261 actccagttg agaaaaattt acattttgtt tggattggag gtcaaataaa tgacactgct
     1321 attaattata taaatcaatg gaaagatgta aatagtgatt ataatgttaa tgttttttat
     1381 gatagtaatg catttttgat aaacacattg aaaaaaactg tagtagaatc agcaataaat
     1441 gatacacttg aatcatttag agaaaactta aatgacccta gatttgacta taataaattc
     1501 ttcagaaaac gtatggaaat aatttatgat aaacagaaaa atttcataaa ctactataaa
     1561 gctcaaagag aagaaaatcc tgaacttata attgatgata ttgtaaagac atatctttca
     1621 aatgagtatt caaaggagat agatgaactt aatacctata ttgaagaatc cttaaataaa
     1681 attacacaga atagtggaaa tgatgttaga aactttgaag aatttaaaaa tggagagtca
     1741 ttcaacttat atgaacaaga gttggtagaa aggtggaatt tagctgctgc ttctgacata
     1801 ttaagaatat ctgcattaaa agaaattggt ggtatgtatt tagatgttga tatgttacca
     1861 ggaatacaac cagacttatt tgagtctata gagaaaccta gttcagtaac agtggatttt
     1921 tgggaaatga caaagttaga agctataatg aaatacaaag aatatatacc agaatatacc
     1981 tcagaacatt ttgacatgtt agacgaagaa gttcaaagta gttttgaatc tgttctagct
     2041 tctaagtcag ataaatcaga aatattctca tcacttggtg atatggaggc atcaccacta
     2101 gaagttaaaa ttgcatttaa tagtaagggt attataaatc aagggctaat ttctgtgaaa
     2161 gactcatatt gtagcaattt aatagtaaaa caaatcgaga atagatataa aatattgaat
     2221 aatagtttaa atccagctat tagcgaggat aatgatttta atactacaac gaataccttt
     2281 attgatagta taatggctga agctaatgca gataatggta gatttatgat ggaactagga
     2341 aagtatttaa gagttggttt cttcccagat gttaaaacta ctattaactt aagtggccct
     2401 gaagcatatg cggcagctta tcaagattta ttaatgttta aagaaggcag tatgaatatc
     2461 catttgatag aagctgattt aagaaacttt gaaatctcta aaactaatat ttctcaatca
     2521 actgaacaag aaatggctag cttatggtca tttgacgatg caagagctaa agctcaattt
     2581 gaagaatata aaaggaatta ttttgaaggt tctcttggtg aagatgataa tcttgatttt
     2641 tctcaaaata tagtagttga caaggagtat cttttagaaa aaatatcttc attagcaaga
     2701 agttcagaga gaggatatat acactatatt gttcagttac aaggagataa aattagttat
     2761 gaagcagcat gtaacttatt tgcaaagact ccttatgata gtgtactatt tcagaaaaat
     2821 atagaagatt cagaaattgc atattattat aatcctggag atggtgaaat acaagaaata
     2881 gacaagtata aaattccaag tataatttct gatagaccta agattaaatt aacatttatt
     2941 ggtcatggta aagatgaatt taatactgat atatttgcag gttttgatgt agattcatta
     3001 tccacagaaa tagaagcagc aatagattta gctaaagagg atatttctcc taagtcaata
     3061 gaaataaatt tattaggatg taatatgttt agctactcta tcaacgtaga ggagacttat
     3121 cctggaaaat tattacttaa agttaaagat aaaatatcag aattaatgcc atctataagt
     3181 caagactcta ttatagtaag tgcaaatcaa tatgaagtta gaataaatag tgaaggaaga
     3241 agagaattat tggatcattc tggtgaatgg ataaataaag aagaaagtat tataaaggat
     3301 atttcatcaa aagaatatat atcatttaat cctaaagaaa ataaaattac agtaaaatct
     3361 aaaaatttac ctgagctatc tacattatta caagaaatta gaaataattc taattcaagt
     3421 gatattgaac tagaagaaaa agtaatgtta acagaatgtg agataaatgt tatttcaaat
     3481 atagatacgc aaattgttga ggaaaggatt gaagaagcta agaatttaac ttctgactct
     3541 attaattata taaaagatga atttaaacta atagaatcta tttctgatgc actatgtgac
     3601 ttaaaacaac agaatgaatt agaagattct cattttatat cttttgagga catatcagag
     3661 actgatgagg gatttagtat aagatttatt aataaagaaa ctggagaatc tatatttgta
     3721 gaaactgaaa aaacaatatt ctctgaatat gctaatcata taactgaaga gatttctaag
     3781 ataaaaggta ctatatttga tactgtaaat ggtaagttag taaaaaaagt aaatttagat
     3841 actacacacg aagtaaatac tttaaatgct gcatttttta tacaatcatt aatagaatat
     3901 aatagttcta aagaatctct tagtaattta agtgtagcaa tgaaagtcca agtttacgct
     3961 caattattta gtactggttt aaatactatt acagatgcag ccaaagttgt tgaattagta
     4021 tcaactgcat tagatgaaac tatagactta cttcctacat tatctgaagg attacctata
     4081 attgcaacta ttatagatgg tgtaagttta ggtgcagcaa tcaaagagct aagtgaaacg
     4141 agtgacccat tattaagaca agaaatagaa gctaagatag gtataatggc agtaaattta
     4201 acaacagcta caactgcaat cattacttca tctttggggg tagctagtgg atttagtata
     4261 cttttagttc ctttagcagg aatttcagca ggtataccaa gcttagtaaa caatgaactt
     4321 gtacttcgag ataaggcaac aaaggttgta gattatttta aacatgtttc attagttgaa
     4381 actgaaggag tatttacttt attagatgat aaaataatga tgccacaaga tgatttagtg
     4441 atatcagaaa tagattttaa taataattca atagttttag gtaaatgtga aatctggaga
     4501 atggaaggtg gttcaggtca tactgtaact gatgatatag atcacttctt ttcagcacca
     4561 tcaataacat atagagagcc acacttatct atatatgacg tattggaagt acaaaaagaa
     4621 gaacttgatt tgtcaaaaga tttaatggta ttacctaatg ctccaaatag agtatttgct
     4681 tgggaaacag gatggacacc aggtttaaga agcttagaaa atgatggcac aaaactgtta
     4741 gaccgtataa gagataacta tgaaggtgag ttttattgga gatattttgc ttttatagct
     4801 gatgctttaa taacaacatt aaaaccaaga tatgaagata ctaatataag aataaattta
     4861 gatagtaata ctagaagttt tatagttcca ataataacta cagaatatat aagagaaaaa
     4921 ttatcatatt ctttctatgg ttcaggagga acttatgcat tgtctctttc tcaatataat
     4981 atgggtataa atatagaatt aagtgaaagt gatgtttgga ttatagatgt tgataatgtt
     5041 gtgagagatg taactataga atctgataaa attaaaaaag gtgatttaat agaaggtatt
     5101 ttatctacac taagtattga agagaataaa attatcttaa atagccatga gattaatttt
     5161 tctggtgagg taaatggaag taatggattt gtttctttaa cattttcaat tttagaagga
     5221 ataaatgcaa ttatagaagt tgatttatta tctaaatcat ataaattact tatttctggc
     5281 gaattaaaaa tattgatgtt aaattcaaat catattcaac agaaaataga ttatatagga
     5341 ttcaatagcg aattacagaa aaatatacca tatagctttg tagatagtga aggaaaagag
     5401 aatggtttta ttaatggttc aacaaaagaa ggtttatttg tatctgaatt acctgatgta
     5461 gttcttataa gtaaggttta tatggatgat agtaagcctt catttggata ttatagtaat
     5521 aatttgaaag atgtcaaagt tataactaaa gataatgtta atatattaac aggttattat
     5581 cttaaggatg atataaaaat ctctctttct ttgactctac aagatgaaaa aactataaag
     5641 ttaaatagtg tgcatttaga tgaaagtgga gtagctgaga ttttgaagtt catgaataga
     5701 aaaggtaata caaatacttc agattcttta atgagctttt tagaaagtat gaatataaaa
     5761 agtattttcg ttaatttctt acaatctaat attaagttta tattagatgc taattttata
     5821 ataagtggta ctacttctat tggccaattt gagtttattt gtgatgaaaa tgataatata
     5881 caaccatatt tcattaagtt taatacacta gaaactaatt atactttata tgtaggaaat
     5941 agacaaaata tgatagtgga accaaattat gatttagatg attctggaga tatatcttca
     6001 actgttatca atttctctca aaagtatctt tatggaatag acagttgtgt taataaagtt
     6061 gtaatttcac caaatattta tacagatgaa ataaatataa cgcctgtata tgaaacaaat
     6121 aatacttatc cagaagttat tgtattagat gcaaattata taaatgaaaa aataaatgtt
     6181 aatatcaatg atctatctat acgatatgta tggagtaatg atggtaatga ttttattctt
     6241 atgtcaacta gtgaagaaaa taaggtgtca caagttaaaa taagattcgt taatgttttt
     6301 aaagataaga ctttggcaaa taagctatct tttaacttta gtgataaaca agatgtacct
     6361 gtaagtgaaa taatcttatc atttacacct tcatattatg aggatggatt gattggctat
     6421 gatttgggtc tagtttcttt atataatgag aaattttata ttaataactt tggaatgatg
     6481 gtatctggat taatatatat taatgattca ttatattatt ttaaaccacc agtaaataat
     6541 ttgataactg gatttgtgac tgtaggcgat gataaatact actttaatcc aattaatggt
     6601 ggagctgctt caattggaga gacaataatt gatgacaaaa attattattt caaccaaagt
     6661 ggagtgttac aaacaggtgt atttagtaca gaagatggat ttaaatattt tgccccagct
     6721 aatacacttg atgaaaacct agaaggagaa gcaattgatt ttactggaaa attaattatt
     6781 gacgaaaata tttattattt tgatgataat tatagaggag ctgtagaatg gaaagaatta
     6841 gatggtgaaa tgcactattt tagcccagaa acaggtaaag cttttaaagg tctaaatcaa
     6901 ataggtgatt ataaatacta tttcaattct gatggagtta tgcaaaaagg atttgttagt
     6961 ataaatgata ataaacacta ttttgatgat tctggtgtta tgaaagtagg ttacactgaa
     7021 atagatggca agcatttcta ctttgctgaa aacggagaaa tgcaaatagg agtatttaat
     7081 acagaagatg gatttaaata ttttgctcat cataatgaag atttaggaaa tgaagaaggt
     7141 gaagaaatct catattctgg tatattaaat ttcaataata aaatttacta ttttgatgat
     7201 tcatttacag ctgtagttgg atggaaagat ttagaggatg gttcaaagta ttattttgat
     7261 gaagatacag cagaagcata tataggtttg tcattaataa atgatggtca atattatttt
     7321 aatgatgatg gaattatgca agttggattt gtcactataa atgataaagt cttctacttc
     7381 tctgactctg gaattataga atctggagta caaaacatag atgacaatta tttctatata
     7441 gatgataatg gtatagttca aattggtgta tttgatactt cagatggata taaatatttt
     7501 gcacctgcta atactgtaaa tgataatatt tacggacaag cagttgaata tagtggttta
     7561 gttagagttg gggaagatgt atattatttt ggagaaacat atacaattga gactggatgg
     7621 atatatgata tggaaaatga aagtgataaa tattatttca atccagaaac taaaaaagca
     7681 tgcaaaggta ttaatttaat tgatgatata aaatattatt ttgatgagaa gggcataatg
     7741 agaacgggtc ttatatcatt tgaaaataat aattattact ttaatgagaa tggtgaaatg
     7801 caatttggtt atataaatat agaagataag atgttctatt ttggtgaaga tggtgtcatg
     7861 cagattggag tatttaatac accagatgga tttaaatact ttgcacatca aaatactttg
     7921 gatgagaatt ttgagggaga atcaataaac tatactggtt ggttagattt agatgaaaag
     7981 agatattatt ttacagatga atatattgca gcaactggtt cagttattat tgatggtgag
     8041 gagtattatt ttgatcctga tacagctcaa ttagtgatta gtgaatagat aaaaatatgt
     8101 taaatatatc ctcttatact taaatatata aaaataaaca aaatgataca ctacataaag
     8161 tgttctatct aatatgaaga tttaccaata aaaaggtgga ctatgatgaa tgcacagtag
     8221 ttcacctttt tatatttcta atggtaacaa aatatttttt tatataaacc taggaggcgt
     8281 tatgaatatg acaatatctt ttttatcaga gcatatattt ataaagttag taattttaac
     8341 tatatcattt gatacattat taggatgttt aagtgcaata aaaagtcgta aatttaattc
     8401 tagttttgga atagatggag gaatcagaaa agtagcaatg atagcatgta tatttttttt
     8461 atcagtagtt gacattctta caaagtttaa ctttttattt atgttaccac aagattgtat
     8521 caatttttta agactaaaac atcttggaat atctgaattt ttctctattt tatttatttt
     8581 atatgaaagt gtaagtatat taaaaaatat gtgcttatgt ggattaccag tacctaagag
     8641 attaaaggaa aaaatagcaa ttttactaga tgcaatgaca gatgaaatga atgctaagga
     8701 tgaaaagtaa gtaatggtag atataataaa gatattaaca aataaaaagt gttatccaaa
     8761 taagaatagc tgaaagttat cataattcat gaaactaata atgaaaacga gggagcagat
     8821 gccaagagac acacaagtat taaatacata taatttcgaa gcaagtgtcc attactatat
     8881 agatgacaag gtagtatatc aaacattggt tcacaaagat ggtgcatggt cagttggtaa
     8941 aatctattaa gctacattag ttacagatat cacaaactat aatagttaaa catagaaata
     9001 tgtgtaaatt gtgatggaaa ttattcaaaa acacaaaaat acgtgatgaa ggacaaaatg
     9061 atatagaaaa taagtatcaa accttaataa atgatttaat tgatagttta aaagttatag
     9121 gaaaaatata taaagaaata aaaacattaa aaaaatataa gatatgttta caaattacta
     9181 tcagacaatc tccttatcta atagaagagt caattaacta attgagtatc tttaaattga
     9241 aatgttagga agtgatttaa atatgaaaac ttaaattata aaaaatcaat attaatttat
     9301 ttttaaaaaa tagaaaggag tgtataagat ttattttcaa agtttaaaaa caagaaaatc
     9361 aatttaaatt tcagaaggaa taaatgtggt tatagaagtg gatttattat caaaaataat
     9421 aatactagga ggtttttatg tctttaatat ctaaagaaga gttaataaaa ctcgcatata
     9481 gcattagacc aagagaaaat gagtataaaa ctatactaac taatttagac gaatataata
     9541 agttaactac aaacaataat gaaaataaat atttacaatt aaaaaaacta aatgaatcaa
     9601 ttgatgtttt tatgaataaa tataaaactt caagcagaaa tagagcactc tctaatctaa
     9661 aaaaagatat attaaaagaa gtaattctta ttaaaaattc caatacaagc cctgtagaaa
     9721 aaaatttaca ttttgtatgg ataggtggag aagtcagtga tattgctctt gaatacataa
     9781 aacaatgggc tgatattaat gcagaatata atattaaact gtggtatgat agtgaagcat
     9841 tcttagtaaa tacactaaaa aaggctatag ttgaatcttc taccactgaa gcattacagc
     9901 tactagagga agagattcaa aatcctcaat ttgataatat gaaattttac aaaaaaagga
     9961 tggaatttat atatgataga caaaaaaggt ttataaatta ttataaatct caaatcaata
    10021 aacctacagt acctacaata gatgatatta taaagtctca tctagtatct gaatataata
    10081 gagatgaaac tgtattagaa tcatatagaa caaattcttt gagaaaaata aatagtaatc
    10141 atgggataga tatcagggct aatagtttgt ttacagaaca agagttatta aatatttata
    10201 gtcaggagtt gttaaatcgt ggaaatttag ctgcagcatc tgacatagta agattattag
    10261 ccctaaaaaa ttttggcgga gtatatttag atgttgatat gcttccaggt attcactctg
    10321 atttatttaa aacaatatct agacctagct ctattggact agaccgttgg gaaatgataa
    10381 aattagaggc tattatgaag tataaaaaat atataaataa ttatacatca gaaaactttg
    10441 ataaacttga tcaacaatta aaagataatt ttaaactcat tatagaaagt aaaagtgaaa
    10501 aatctgagat attttctaaa ttagaaaatt taaatgtatc tgatcttgaa attaaaatag
    10561 ctttcgcttt aggcagtgtt ataaatcaag ccttgatatc aaaacaaggt tcatatctta
    10621 ctaacctagt aatagaacaa gtaaaaaata gatatcaatt tttaaaccaa caccttaacc
    10681 cagccataga gtctgataat aacttcacag atactactaa aatttttcat gattcattat
    10741 ttaattcagc taccgcagaa aactctatgt ttttaacaaa aatagcacca tacttacaag
    10801 taggttttat gccagaagct cgctccacaa taagtttaag tggtccagga gcttatgcgt
    10861 cagcttacta tgatttcata aatttacaag aaaatactat agaaaaaact ttaaaagcat
    10921 cagatttaat agaatttaaa ttcccagaaa ataatctatc tcaattgaca gaacaagaaa
    10981 taaatagtct atggagcttt gatcaagcaa gtgcaaaata tcaatttgag aaatatgtaa
    11041 gagattatac tggtggatct ctttctgaag acaatggggt agactttaat aaaaatactg
    11101 ccctcgacaa aaactattta ttaaataata aaattccatc aaacaatgta gaagaagctg
    11161 gaagtaaaaa ttatgttcat tatatcatac agttacaagg agatgatata agttatgaag
    11221 caacatgcaa tttattttct aaaaatccta aaaatagtat tattatacaa cgaaatatga
    11281 atgaaagtgc aaaaagctac tttttaagtg atgatggaga atctatttta gaattaaata
    11341 aatataggat acctgaaaga ttaaaaaata aggaaaaagt aaaagtaacc tttattggac
    11401 atggtaaaga tgaattcaac acaagcgaat ttgctagatt aagtgtagat tcactttcca
    11461 atgagataag ttcattttta gataccataa aattagatat atcacctaaa aatgtagaag
    11521 taaacttact tggatgtaat atgtttagtt atgattttaa tgttgaagaa acttatcctg
    11581 ggaagttgct attaagtatt atggacaaaa ttacttccac tttacctgat gtaaataaaa
    11641 attctattac tataggagca aatcaatatg aagtaagaat taatagtgag ggaagaaaag
    11701 aacttctggc tcactcaggt aaatggataa ataaagaaga agctattatg agcgatttat
    11761 ctagtaaaga atacattttt tttgattcta tagataataa gctaaaagca aagtccaaga
    11821 atattccagg attagcatca atatcagaag atataaaaac attattactt gatgcaagtg
    11881 ttagtcctga tacaaaattt attttaaata atcttaagct taatattgaa tcttctattg
    11941 gtgattacat ttattatgaa aaattagagc ctgttaaaaa tataattcac aattctatag
    12001 atgatttaat agatgagttc aatctacttg aaaatgtatc tgatgaatta tatgaattaa
    12061 aaaaattaaa taatctagat gagaagtatt taatatcttt tgaagatatc tcaaaaaata
    12121 attcaactta ctctgtaaga tttattaaca aaagtaatgg tgagtcagtt tatgtagaaa
    12181 cagaaaaaga aattttttca aaatatagcg aacatattac aaaagaaata agtactataa
    12241 agaatagtat aattacagat gttaatggta atttattgga taatatacag ttagatcata
    12301 cttctcaagt taatacatta aacgcagcat tctttattca atcattaata gattatagta
    12361 gcaataaaga tgtactgaat gatttaagta cctcagttaa ggttcaactt tatgctcaac
    12421 tatttagtac aggtttaaat actatatatg actctatcca attagtaaat ttaatatcaa
    12481 atgcagtaaa tgatactata aatgtactac ctacaataac agaggggata cctattgtat
    12541 ctactatatt agacggaata aacttaggtg cagcaattaa ggaattacta gacgaacatg
    12601 acccattact aaaaaaagaa ttagaagcta aggtgggtgt tttagcaata aatatgtcat
    12661 tatctatagc tgcaactgta gcttcaattg ttggaatagg tgctgaagtt actattttct
    12721 tattacctat agctggtata tctgcaggaa taccttcatt agttaataat gaattaatat
    12781 tgcatgataa ggcaacttca gtggtaaact attttaatca tttgtctgaa tctaaaaaat
    12841 atggccctct taagacagaa gatgataaaa ttttagttcc tattgatgat ttagtaatat
    12901 cagaaataga ttttaataat aattcgataa aactaggaac atgtaatata ttagcaatgg
    12961 aggggggatc aggacacaca gtgactggta atatagatca ctttttctca tctccatcta
    13021 taagttctca tattccttca ttatcaattt attctgcaat aggtatagaa acagaaaatc
    13081 tagatttttc aaaaaaaata atgatgttac ctaatgctcc ttcaagagtg ttttggtggg
    13141 aaactggagc agttccaggt ttaagatcat tggaaaatga cggaactaga ttacttgatt
    13201 caataagaga tttataccca ggtaaatttt actggagatt ctatgctttt ttcgattatg
    13261 caataactac attaaaacca gtttatgaag acactaatat taaaattaaa ctagataaag
    13321 atactagaaa cttcataatg ccaactataa ctactaacga aattagaaac aaattatctt
    13381 attcatttga tggagcagga ggaacttact ctttattatt atcttcatat ccaatatcaa
    13441 cgaatataaa tttatctaaa gatgatttat ggatatttaa tattgataat gaagtaagag
    13501 aaatatctat agaaaatggt actattaaaa aaggaaagtt aataaaagat gttttaagta
    13561 aaattgatat aaataaaaat aaacttatta taggcaatca aacaatagat ttttcaggcg
    13621 atatagataa taaagataga tatatattct tgacttgtga gttagatgat aaaattagtt
    13681 taataataga aataaatctt gttgcaaaat cttatagttt gttattgtct ggggataaaa
    13741 attatttgat atccaattta tctaatacta ttgagaaaat caatacttta ggcctagata
    13801 gtaaaaatat agcgtacaat tacactgatg aatctaataa taaatatttt ggagctatat
    13861 ctaaaacaag tcaaaaaagc ataatacatt ataaaaaaga cagtaaaaat atattagaat
    13921 tttataatga cagtacatta gaatttaaca gtaaagattt tattgctgaa gatataaatg
    13981 tatttatgaa agatgatatt aatactataa caggaaaata ctatgttgat aataatactg
    14041 ataaaagtat agatttctct atttctttag ttagtaaaaa tcaagtaaaa gtaaatggat
    14101 tatatttaaa tgaatccgta tactcatctt accttgattt tgtgaaaaat tcagatggac
    14161 accataatac ttctaatttt atgaatttat ttttggacaa tataagtttc tggaaattgt
    14221 ttgggtttga aaatataaat tttgtaatcg ataaatactt tacccttgtt ggtaaaacta
    14281 atcttggata tgtagaattt atttgtgaca ataataaaaa tatagatata tattttggtg
    14341 aatggaaaac atcgtcatct aaaagcacta tatttagcgg aaatggtaga aatgttgtag
    14401 tagagcctat atataatcct gatacgggtg aagatatatc tacttcacta gatttttcct
    14461 atgaacctct ctatggaata gatagatata tcaataaagt attgatagca cctgatttat
    14521 atacaagttt aataaatatt aataccaatt attattcaaa tgagtactac cctgagatta
    14581 tagttcttaa cccaaataca ttccacaaaa aagtaaatat aaatttagat agttcttctt
    14641 ttgagtataa atggtctaca gaaggaagtg actttatttt agttagatac ttagaagaaa
    14701 gtaataaaaa aatattacaa aaaataagaa tcaaaggtat cttatctaat actcaatcat
    14761 ttaataaaat gagtatagat tttaaagata ttaaaaaact atcattagga tatataatga
    14821 gtaattttaa atcatttaat tctgaaaatg aattagatag agatcattta ggatttaaaa
    14881 taatagataa taaaacttat tactatgatg aagatagtaa attagttaaa ggattaatca
    14941 atataaataa ttcattattc tattttgatc ctatagaatt taacttagta actggatggc
    15001 aaactatcaa tggtaaaaaa tattattttg atataaatac tggagcagct ttaactagtt
    15061 ataaaattat taatggtaaa cacttttatt ttaataatga tggtgtgatg cagttgggag
    15121 tatttaaagg acctgatgga tttgaatatt ttgcacctgc caatactcaa aataataaca
    15181 tagaaggtca ggctatagtt tatcaaagta aattcttaac tttgaatggc aaaaaatatt
    15241 attttgataa tgactcaaaa gcagtcactg gatggagaat tattaacaat gagaaatatt
    15301 actttaatcc taataatgct attgctgcag tcggattgca agtaattgac aataataagt
    15361 attatttcaa tcctgacact gctatcatct caaaaggttg gcagactgtt aatggtagta
    15421 gatactactt tgatactgat accgctattg cctttaatgg ttataaaact attgatggta
    15481 aacactttta ttttgatagt gattgtgtag tgaaaatagg tgtgtttagt acctctaatg
    15541 gatttgaata ttttgcacct gctaatactt ataataataa catagaaggt caggctatag
    15601 tttatcaaag taaattctta actttgaatg gtaaaaaata ttactttgat aataactcaa
    15661 aagcagttac cggatggcaa actattgata gtaaaaaata ttactttaat actaacactg
    15721 ctgaagcagc tactggatgg caaactattg atggtaaaaa atattacttt aatactaaca
    15781 ctgctgaagc agctactgga tggcaaacta ttgatggtaa aaaatattac tttaatacta
    15841 acactgctat agcttcaact ggttatacaa ttattaatgg taaacatttt tattttaata
    15901 ctgatggtat tatgcagata ggagtgttta aaggacctaa tggatttgaa tattttgcac
    15961 ctgctaatac ggatgctaac aacatagaag gtcaagctat actttaccaa aatgaattct
    16021 taactttgaa tggtaaaaaa tattactttg gtagtgactc aaaagcagtt actggatgga
    16081 gaattattaa caataagaaa tattacttta atcctaataa tgctattgct gcaattcatc
    16141 tatgcactat aaataatgac aagtattact ttagttatga tggaattctt caaaatggat
    16201 atattactat tgaaagaaat aatttctatt ttgatgctaa taatgaatct aaaatggtaa
    16261 caggagtatt taaaggacct aatggatttg agtattttgc acctgctaat actcacaata
    16321 ataacataga aggtcaggct atagtttacc agaacaaatt cttaactttg aatggcaaaa
    16381 aatattattt tgataatgac tcaaaagcag ttactggatg gcaaaccatt gatggtaaaa
    16441 aatattactt taatcttaac actgctgaag cagctactgg atggcaaact attgatggta
    16501 aaaaatatta ctttaatctt aacactgctg aagcagctac tggatggcaa actattgatg
    16561 gtaaaaaata ttactttaat actaacactt tcatagcctc aactggttat acaagtatta
    16621 atggtaaaca tttttatttt aatactgatg gtattatgca gataggagtg tttaaaggac
    16681 ctaatggatt tgaatacttt gcacctgcta atactcataa taataacata gaaggtcaag
    16741 ctatacttta ccaaaataaa ttcttaactt tgaatggtaa aaaatattac tttggtagtg
    16801 actcaaaagc agttaccgga ttgcgaacta ttgatggtaa aaaatattac tttaatacta
    16861 acactgctgt tgcagttact ggatggcaaa ctattaatgg taaaaaatac tactttaata
    16921 ctaacacttc tatagcttca actggttata caattattag tggtaaacat ttttatttta
    16981 atactgatgg tattatgcag ataggagtgt ttaaaggacc tgatggattt gaatactttg
    17041 cacctgctaa tacagatgct aacaatatag aaggtcaagc tatacgttat caaaatagat
    17101 tcctatattt acatgacaat atatattatt ttggtaataa ttcaaaagcg gctactggtt
    17161 gggtaactat tgatggtaat agatattact tcgagcctaa tacagctatg ggtgcgaatg
    17221 gttataaaac tattgataat aaaaattttt actttagaaa tggtttacct cagataggag
    17281 tgtttaaagg gtctaatgga tttgaatact ttgcacctgc taatacggat gctaacaata
    17341 tagaaggtca agctatacgt tatcaaaata gattcctaca tttacttgga aaaatatatt
    17401 actttggtaa taattcaaaa gcagttactg gatggcaaac tattaatggt aaagtatatt
    17461 actttatgcc tgatactgct atggctgcag ctggtggact tttcgagatt gatggtgtta
    17521 tatatttctt tggtgttgat ggagtaaaag cccctgggat atatggctaa aatatatgtt
    17581 tgataaaaaa ttattcctgt gctactaaga aattattttt atataataaa tattgagatt
    17641 taattaaaag tcatgtgtta ttgtaataca tgacttttag ttaaaatttt tctatcattt
    17701 aataatctat tattcttgac tattttataa taaaattcat atatggaaat attaatacta
    17761 aataattaat agttgataaa aaatagataa tatgctaaaa gcaaaaacta atttagagcc
    17821 ttgtaactgt ttatttgcaa ttataaaaac atctttaaac atattgacta taatataaaa
    17881 tattaactat aatacaaaac aatattaatt aattttctct acagctatcc ctggtatagt
    17941 tatatttcca cccatagttg attcataagt tatagttcca gcacttatac ctcttatagt
    18001 tatgtaatca tcctctaata ctcttgaagg agttattgat tttttataac tacatagtac
    18061 aaccttatca taatttccag acacagctaa tcttatttgc acctcatcac catcttcaat
    18121 aacttgaata accttacctt caaattttac ctttttgtac ttataatcat caggtgttct
    18181 agctaattgg tcataagtaa taccagtatc atatcctttc ttctcctctt cttctttttt
    18241 gcgttgttct tcagcctttt tagcttcttc agctttttta gcttcttcag ctttacgttg
    18301 attttcagct tcaatagctt tcttttcgtc gtctttcatt ttgaaccatg gttcagcatc
    18361 agacaatttg ctatttaaag tttctatttc tgttttttga gaatctataa ctgatgtttg
    18421 gttagaaatg acctcctcat ggtcttcaga acaagatggt gaggatatat tgccaaaaaa
    18481 cacgcctaaa ataaatgcca gtagagcaat accctttgtg ctcttaaaga atttaattat
    18541 tttcttagag cttccttttc cttcattact aaattcgtta ccctcatttt ttttagaaaa
    18601 cataatacaa tctccctttt attagatata ttttatttta aaagttaaaa acttaaaata
    18661 actagttgac taaaaattat atattcatat tttcctaaaa tatatttccc ctaagcataa
    18721 ttttacaaaa taaagtaaga agattcaata tattttgaaa aaataagata aaaatgtcag
    18781 attataatat aattttcttg aaggtgaatt ttatatatta aattaaacat aaagtatttt
    18841 atttgtataa aactatatta tgatgtaatt aagtgactca gtgatttaga ggtggtaaaa
    18901 tatatatata tgaaagagca taaataaatt gatataataa aaaattaaat attaaatatt
    18961 aactataata aaaaaatatc tggtaatagg tataatataa aaagaatata ccagaaagaa
    19021 ggtgaagtat gggagaacta caaaaaattc caggggtagg gaaagcaaca gaaaaatctt
    19081 taatcatgtt aggatataca actattaaat cacttaaaga tgcaaaccca gcacaaatgt
    19141 atgaaaagga atgtttaatg cgtggacagc acatagacag atgtcagtta tatgtataca
    19201 gatgtgcagt atattttgca tcaactgaaa atccagaacc agaaaaatta aagtggtggt
    19261 attggaaaga ttaaaaaatc aaaaaagtta gacataaaaa agagttgaat atccgtttta
    19321 aataataaaa actaatactc aactcttttt tagtcgtaaa ttttatgtaa atctatttgt
    19381 atggctaaat atacccatca ataaatgtat aaatatacta atcaacaaat gactaaacat
    19441 actacctaac aaaggattaa ataaattcct taacaaagca ttctaaaaca attaattaga
    19501 aactgtttct tcaagccatt ttctacattg ctcaatattt accatagggt caaaaccttg
    19561 gtcttttccc ttatttaaaa gcatatcaca agggaaagta tcacattcac cacaatgatt
    19621 aagttcctta ctttcacagc aagttttaac cttacattct ccaccccaaa atggtttttc
    19681 catagttggg caaccagtgc aatttacttg ttcttttttt gtacaactgt cacaacagac
    19741 accacatctt gattcaaaca tattcaaaca tcctttccat tatttaaaaa tattataaaa
    19801 tgattttaga tgaatacaaa agtgcaaata gttgatttta ggtcatctaa atgttaaaca
    19861 taaaattatt agtactggta aatttataaa aactattcca aaaatctttt tgaatatttc
    19921 aaaacacaat aaattacttc aaatcccctt gaatatattt tacagcatta tagattgctt
    19981 taaatctctt tgaatattct acaagactat agattagttt aaatcccttt gaatatattt
    20041 tacaacatta tagattgttt taaatctctt tgaatattct acaagactat agattagttt
    20101 aaatcccttt gaatatttca aaacaccata gattacttta aatccctttg aatgttctat
    20161 aacactataa attactttta acttttatat aaccataaag tttttatctg gcactttaaa
    20221 tggagtttta tatcaaattt gccttccatc gaataaccaa acttaattta attacacatt
    20281 ccaagattca aatattcatt caatatattt gataattcta tgttatagct ataattaaat
    20341 atagattatt aaagttaaat atttatttaa tatattgaat gattttttac ctatatttaa
    20401 ttaagtttca ttatataata taaaaattgt ttttgcatta agttttaata taatacataa
    20461 taattttaaa taataatatt attatatatt tttaaatttt aggagtatat ctattatata
    20521 gcgagtagat aaaacatata aaattcaaat aaaagatata tatttttaaa taaaatggat
    20581 atagatttca actaaaaaga atataaattt caaacccaaa aatatctagc atttaccatt
    20641 aagaaataac atcattcttt ctaaaatttc tattggcaat ttcagaaaat actatagtag
    20701 taataaatgc aacacatatt gtaactatag tgtcattaac atttaaagca gattgcttta
    20761 taacccccat agcactacct aacatagaat aagggaaaaa tataccaaca gcaggttttg
    20821 ctactattaa tcccatacca aatagagaaa ggcaaagact aataccaata ggagttgcaa
    20881 aacttctaat ctttatagac atgtataatt gtatagaagc tattgaaata gaaataatcc
    20941 aacctttagc aatccaacca gtcaattctt taggtacact accagaaaaa ccaaacatat
    21001 ttcctgcaac tatataaaag ataacaaaga aaacttgtgt aatagctgta agtattgaaa
    21061 ctactgtaag tttagataaa aagatatttt ttaaattaac tggcagtgtc attacattat
    21121 tccaattatg attcatatgt tcaagcctac aaatatatgc acaaaagatt gcaattaaga
    21181 taggaaagaa aaattcccca taaaaaagac taacttgagt ccataagctg taccattctt
    21241 ttttgagtat gccttgattt agataaaaat taccagaacc aatcaacaca cttataagtg
    21301 gcaaagctaa taatacatac catataaaag aattttttaa ctttagaatt tctcccaaga
    21361 ctgacttcct taacatttaa atccctccta tacttctttt tttaataaat gatttcttcc
    21421 aatataataa attagcattc caattaagaa aactaaaatc gtgatagaaa aattcatatc
    21481 aattctatag acagatgaac ctaaaacatt atcataagca taacttaaag gtgataactc
    21541 taggtaataa gaccatataa acaatctacg aataccttga taaaacaaac ctgatgtcaa
    21601 acctataaaa ctaccaatca tgccaaatgt aattgcaatc atttgatttg gaattacagt
    21661 tgcaatccat aggtgtagtg caatgatagc aatacttaca agaattgttc ctaatgtgta
    21721 ttttaaaagt aaagatacag aaattgactc aataacccct ctaaaatgtc caaacaacac
    21781 aatagataac acttgcatca atacaggtat agataccaaa atagcagaac ataaaaattt
    21841 agataaataa atactattta aagatgtcac agaagatttt aaaagcttcc atgtatctcc
    21901 tttatgttct atatcgctta tacgtgatgt gattattgat attaagatag gaaagaatag
    21961 accatttaaa cttgcaaaac tcataagcat ataggaatat tcaaatccac ctaacatatc
    22021 tggattacgt gtaatagctc tatttgaatt tacgatacac cacattattt caacagctgc
    22081 aaataaaaag gtcatcagaa taatcttctt tcttttaagt ttataaaatt ctagaccaag
    22141 gtatttcatt ataaagtcac cgccttacca gtaagttcta agaatatatc ttccaagctt
    22201 tttttatgtt cttctattct aaatacatct atatttgaat ggacaagcat accatttatt
    22261 ttagccacat ctgagtcttt taaattttca atagtcaagt acccatcttg tataagtgac
    22321 atatatcctt tagtatttaa tagtttttgt gcagatacaa cattcttagt tttgatagca
    22381 atctgacttt gacctctatt atgaagttct tttatgctat cttgaaaaac cagttcgcca
    22441 tgatttatta ttcctattga tgtggcaatt tggtcaattt cacttaaaag atggctagag
    22501 attagaacag tcatcccgta tttttctggt agagatttta ttaattctct aatttcctca
    22561 atccctgctg ggtcgagtcc atttgtaggt tcatcaagta ttaataattt gggaaacttc
    22621 attattgcca tagcaatacc aagacgttgc ttcataccta aagaatattg actaactttt
    22681 ttattttttt gattttctaa ccttacaatt tttaatgctt catttacatt ttttttaggt
    22741 aaatctaaga gtctttgcat tatggtcatg ttttcaagcc ctgtaagatg accatagtat
    22801 gatggagatt ctatcaaaga acctatatct tttaaaattg atattctatt tttttcattt
    22861 aactctttac ctaaaatatt aatatttcct tgtgtgggtt tagcaagtcc aagaagcatt
    22921 ttaagagtgg tagattttcc agctccatta ggacccaaaa aaccatatac agctccttgt
    22981 ggaactctta ggtctatatc ctttactcta aatattttat tgtattcctt tgaaagtctt
    23041 tgtgttctaa ttatcatttc catatgtttc atcccctttt ttaatctgtg cttattgatt
    23101 cttttaactt atatcagtat aataacttgg ttacatttca attagctgaa atttacctta
    23161 caataacctt aaaagtctat ttaggcaaag ttgtgaaaat gggtatatgg tatactaaag
    23221 gagggtgatg attatggagt caataaaaga taaaaaaata cttgtggttg atgaccacaa
    23281 ggaattatta aaaatgatag atgaaatcct gagaaaagag ggatttagta gagtattttt
    23341 agcatcaagt tatgaggaag ctgttaaggt atttagaaat gtaaagccag attgtgcaat
    23401 tttagatgtt gtattgccag atggagatgg tttttctatt atgagaaaaa ttagagagac
    23461 atctaaaata ccagtgattt ttctctctgc aagaggtgaa gatgaagata gattgattgg
    23521 tttgggctta ggggctgacg attatatagt aaagccattt ttaccaaagg aacttacttt
    23581 aaggcttgtg ggtatattaa atcgtgtata tgtgcctata gaagaagagg agttgccagt
    23641 atttaaactg ggagattctg ttgttgtgaa tttaaatagt gcatgtgttg agaaagaagg
    23701 gcaagagatt tctttaacag ctaaagagca ttcgttgctt ttaaagttgt atgaaaataa
    23761 agggagaatt gttactaatg attcactatg tcaagccatt tggggagatg atatgtatgg
    23821 atatgaaaat acccttatgg ttcatgttag aagggttaga gagaagatag aaaaaactcc
    23881 atctacacct aaacatctta ttacagtaag aggtcttgga tataagttga tgattaatta
    23941 attttagata ttagaataaa agaaatcaag aggagtgatt taattttgga tagtgtaaag
    24001 tacatattga ggcgatttat aggttcaagt atcttgattt cattactttt tattgtatta
    24061 aatatagcag gttttcttct gttttcatat atgttatttg tatctaaata ctctgataat
    24121 ttagatacaa gtgatagcag agaaataaaa tcaaacttga ttatgattga agataatttg
    24181 gttttaaaag atggaaagtt tattttagat gattctagta aggaaatact acataaaaat
    24241 aaagtttggg caatgttaat tgataacaat ggagatagaa tatggggatt tgatttacca
    24301 aaagaaattc caagtcatta tactttgaca gatgtagcaa agttttcaag gttcttttta
    24361 aaggactatc ctgtgtatgt atgggaacat ccaaatggaa tattagtaac aggttatcca
    24421 aaagacaagt acactaagtt taaccttact tatacggtta aggaaataga acaatttcct
    24481 atgttaataa taggtatgtt tttggttaat gcaatagtta cttttttaat agctctattc
    24541 ataggtttaa aaatggtgaa atctataaaa ccaattatta ctggcataaa gcttatgtca
    24601 aaaggagagc cagtactttt acaagaaaaa ggaatactaa gtgatatttc aaaatctatt
    24661 aatactgtat ctaaagagtt gcaaatgaaa gatgaaaaac ttaggaagaa agaggaagct
    24721 aggtctaact ggattgcagg aatatctcat gatataagaa ctccactttc aatgataatt
    24781 ggatatgctg gagaacttga agaaagcagt agcctttcaa atagagaaca agagcaagtg
    24841 tctattatat gcaatcaagg gattaaaatc agagaattag taaatgacct aaatttagtg
    24901 tctaaacttg aatataatat gcaagcattg aattgtgata agattagagt ttctgcgttt
    24961 ttgagagagc ttatttctga gtttataaat aataatttgg ataatgactt ttacgttgaa
    25021 cttgatatac taaatgaaga tattattata gatgcagata aaaaattatt aaaaagggct
    25081 attagtaatt taatacaaaa tagtataact cataaccaac aaggatgtaa tataagggtt
    25141 acctctaagt ctgatttaga tttttgctat ataattgttg aagatgatgg aaaaggtatg
    25201 agtcaagaaa gaattaatag tttattaaag agccaaaatg gactaagtga ggcatatgcc
    25261 aaaggtcaaa atcatggtct aggtattttg atagtatctg gcattattaa tgcacataga
    25321 ggtaaattag atattacgag cattgatagt cagggactaa aaacaatact aaaattacct
    25381 ctaattaagt gatattttat aaaataataa cagataagaa tgaagaatga aaatattttg
    25441 aaaataattt tattctttat tgacaaatta actctattag agtagaataa ggataaattc
    25501 ttttcttgtc aagttttatt aaagtaaaga gtaacttgtg ctttatgcgc ttatggctga
    25561 gttactcatg gtatcaaaat tttcatagaa ataatatttt ggaattattg taaggttatt
    25621 aaattcttta gataattcca ttttttttat tttttagtta atatttaatt ttattattga
    25681 caaaaaaatt ctactaaaat agaattatgg tatagtgttt tttaatttta agaaaaaata
    25741 taatgacatc ctaaaaaagt tttaattata cgctgttctg tgtagttata atagcttcta
    25801 tgtaactatt gtaagtatat tattatagtt atttatttaa agtacgataa atgttttaaa
    25861 ttgaagtatt ttgcgccatt aagttctact aaagtagagt ttttgtgtag tatttttaga
    25921 aataacatat atatatatgt atttatgttg aaatatatgg aaaatttata atataattaa
    25981 tgaaaaaatt taaactttgt aatatataaa taaaaaaact ctaaaataga aggatataat
    26041 tatatagaat gtttcaatta aacaaggtaa aaactataat cttaaaatta aaattaacat
    26101 tattcttaag aagcaagaaa tttagaaagt aggaagttta gtgataagtg gtagtaagta
    26161 agaaatttag gaagtgggaa gtttagttat aagtagtagt aagtaagaaa tttagtaagt
    26221 gggaagttta gtgataagtg gtagtaagta agaaatttag gaagtgggaa gtttagttat
    26281 aagtagtagt aagtaagaaa tttagtaagt gggaagttta gtagtaataa tttatagcaa
    26341 gtaagaaatt taggaagtag gaagtttagt aataatttgt agcaagtaag aaacttaggg
    26401 agtaggaagt ttagtaataa tttatagcaa gtaagaaatt tagggagtag gaagtttagt
    26461 aataatttgt agtaagtaag aaatttagaa agtaggaaat ttagtaataa tttatagtaa
    26521 gtaagaaaat tagggagtag gaagtttagt aataatttat agtaagtaag aaatttagaa
    26581 agtaggaagt ttagtaataa tttatagcaa gtaagaaatt tagggagtag gaagtttagt
    26641 aataatttgt agcaagtaag aaatttagaa agtaggaagt ttagtagtaa tttatagtaa
    26701 gtaagaaatt tagtaagtga gaagtttagt tataatttat agtaagtaag aaatttagta
    26761 agtgagaagt tcagtaataa gttgtagtaa ataaaaagtt taggaagtag gaagttcagt
    26821 aataagttgt agtaaataaa aaatttagga agtaggattt actgaaatac aaatatttaa
    26881 aatcaaagag tttaaaagaa aggagagcta ctggacaagt atccaaaata gatagctgag
    26941 tacaaaatat ttcataaaat taagcaatat aatacaagag aattttgaca ttatttatat
    27001 atatttaccg tgtacaaata gctaaattta ggattaagat tgaaaaatat cttataagtc
    27061 tgagcttata taaatccgta taagatgtat ttaatcgaaa aattttatta tggatattgc
    27121 ttgtctatat tctgagtagc aaggttttat catgactata aaaaagttgc cacaatcaga
    27181 attaaagata atgaaattta tatggaaatc agattccaaa gtaacatcta gagatattgt
    27241 tttaggaatg gagcaaaaat atcaatggaa acaaacgaca actttgactc ttttatctag
    27301 attagtagta aaaagatttc taaattctca aaagatagat aaatatacgc attatgaagt
    27361 tttaattaaa gaaaaggaat acataggagt tgagacaaga gattttttta gaaatattca
    27421 tgattcttct ataaaaagtt tattgttgtc attacatgaa aatattaatt tgagcaaaga
    27481 tgatatttta cttattgaag agtggataaa aaatctaaaa gaagaggaga aagacgtata
    27541 agcaaacgta tttcttatag catcaatata aagtgtatgt aagtgtattt atgtaatata
    27601 ttagtctact taagtaatat gacaaatgat tataagtgga ttatgatact ataatgtgaa
    27661 tctaaataaa ttaaatataa attaatagtg gatattctat ttaattaaat ttaaaaagct
    27721 acctttactt ataagtataa ttaaggtagc tttttaaata gaggtagtgt aattaaagag
    27781 aatttttaaa tataaattgt gaagctttaa tatagatgat aatatatatt ttgcaaatat
    27841 gacacagtgt tttcgtattt aagatgataa aataaatagg aattaatgat gatattgaaa
    27901 aaataaaaat aaaggattaa tataagatat taaagagata gagataaaag tgttaacaga
    27961 agatattgaa aaaataaaag attgatataa gatactgaag aggtagaaac aaaagtatt
//
LOCUS       DAMJXI010000046        27889 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.048, whole genome shotgun sequence.
ACCESSION   DAMJXI010000046 DAMJXI010000000
VERSION     DAMJXI010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27889
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.048"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(295..1050)
                     /locus_tag="PC465_002542"
     CDS             complement(295..1050)
                     /locus_tag="PC465_002542"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDF2649828.1"
                     /translation="MLKVIISGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHS
                     DTKLYKTMTDVTEKTDVIIDFSHHETLEPILSYALKNNTPVVLATTGYDENDLNKIEE
                     ASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
                     NAIREVLPESENTHGRYGRDCKRKPNEIGIHSIRGGNIISDHDVIFAGDNEVLTLSHH
                     SQSDEVFANGSIVAAKFLIGKQSGLYKMSDILG"
     gene            1490..2479
                     /locus_tag="PC465_002543"
     CDS             1490..2479
                     /locus_tag="PC465_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HDF2649829.1"
                     /translation="MLKEEKTYQEKDAKVFNGVAALIMILLFLVVSIGIMVFGIVKLD
                     SGFTGIGSLMLILGLVFIVVDFILFFGLRMINPKEAIVLVLFGNYYGTIKKEGYYWVN
                     PFCSAINPAVSRINVSKSSSDEKVDISTNSRGKKVSLKTMTLNNEKQKVNDLLGNPII
                     IGVVVIWKVIDATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSS
                     QEIADRLKDELQSRVDIAGIEVCEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVE
                     GAVSMVEMALTNLSENNVVTLDEERKAAMVSNLLVVLCGNKDAQPVVNSSSIY"
     gene            complement(2835..3551)
                     /gene="dapD"
                     /locus_tag="PC465_002544"
     CDS             complement(2835..3551)
                     /gene="dapD"
                     /locus_tag="PC465_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HDF2649830.1"
                     /translation="MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFG
                     NNGSYIFVGDYDDIMEVLDKHGNDITDTHVEYDRRNSAIPLKNTLSEHARIEPGAIIR
                     DMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
                     PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIK
                     MKDEKTADKTKLMEDLRNLD"
     gene            complement(3775..4524)
                     /locus_tag="PC465_002545"
     CDS             complement(3775..4524)
                     /locus_tag="PC465_002545"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDF2649831.1"
                     /translation="MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDL
                     KIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDDEMNKIREAA
                     KVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
                     IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQ
                     SRGIFASGSIAAAKYLVKQKPGFYNMDSMLG"
     gene            complement(4591..5478)
                     /locus_tag="PC465_002546"
     CDS             complement(4591..5478)
                     /locus_tag="PC465_002546"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDF2649832.1"
                     /translation="MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCG
                     TTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALL
                     IITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVA
                     VKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDL
                     VAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDP
                     ANLEVLKKELVNFGLKVNA"
     gene            complement(5595..6596)
                     /locus_tag="PC465_002547"
     CDS             complement(5595..6596)
                     /locus_tag="PC465_002547"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HDF2649833.1"
                     /translation="MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGS
                     KVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWR
                     MNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
                     SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKIL
                     DNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEY
                     PTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV"
     gene            complement(7021..7902)
                     /locus_tag="PC465_002548"
     CDS             complement(7021..7902)
                     /locus_tag="PC465_002548"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDF2649834.1"
                     /translation="MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENGTDALVVCG
                     TTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLL
                     IITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVVAELAKIDNIVA
                     VKEASGDLAQVAEIAKLVPKDFAIYSGNDDTILPLLSLGGSGVISVLANICPKETHDL
                     VTKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEE
                     TNLNVLKQELTNFGFKF"
     gene            8225..9418
                     /locus_tag="PC465_002549"
     CDS             8225..9418
                     /locus_tag="PC465_002549"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HDF2649835.1"
                     /translation="MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPDAESFRAILY
                     GSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTAEWT
                     VYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYI
                     KTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQ
                     NASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASIS
                     GAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIP
                     CIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAK
                     HFFSC"
     gene            9624..10742
                     /locus_tag="PC465_002550"
     CDS             9624..10742
                     /locus_tag="PC465_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HDF2649836.1"
                     /translation="MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGI
                     EYEVYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYL
                     NDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNIDEIYGLHIYPELPEGYVGT
                     REGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVSSLQTIVSRNISPIDNAV
                     LTIGRIEGGARRNIIAENIKMEGTMRCFSPEVYEKMKLRVRELARGFELAYNCKVNIN
                     IIDDYIAVKNDKDLYQEFVEAIGSDTVVELEPLMISEDFSYYQKEVPGLFFMLGSRNE
                     EKGFVNGLHNINFNFDEKICVNALNVYSKLLKYKEAID"
     gene            10873..11118
                     /locus_tag="PC465_002551"
     CDS             10873..11118
                     /locus_tag="PC465_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HDF2649837.1"
                     /translation="MKEKVQREKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERG
                     WAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI"
     gene            11105..11851
                     /locus_tag="PC465_002552"
     CDS             11105..11851
                     /locus_tag="PC465_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF2649838.1"
                     /translation="MSQYSDFAFVYDELMNEVDYNGWVKYIEDIIDSEGVKVKNILEL
                     ACGTGNLTIPLAKKNYDIAGIDISDEMLSVAREKAEKEGVELVLLQQDISELDFEISD
                     LDCVLCACDGFNYITYDDDLENVFSKTYELLKKDGIFIFDISSFYKLANILGNNMYGE
                     NREDIAYMWQNYFDEEENLIEMELTFFIKDECGKFERFEEIHQQRAYTEDEIVDMLEK
                     SGFKDIKYYGDFTFDKPSEESQRIFFVCKK"
     gene            12134..13009
                     /gene="hslO"
                     /locus_tag="PC465_002553"
     CDS             12134..13009
                     /gene="hslO"
                     /locus_tag="PC465_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HDF2649839.1"
                     /translation="MRDYVLRATSGNGQVRAFVATTRNTVEEARRLHETTKVATAALG
                     RTLTATSIMGLMMKNDSDKLTVIIKGGGPIGTIIATSDSKGMVKGYVGNPQVEVEDYP
                     NGKLNVAAAVGTEGVVKVIKDLGLREPYNGTYPLVSGEIAEDFTYYFAVSEQTPSVVA
                     LGVLTKEDEVEFAGGFIVQLMPDAEEETIAKLEENVAKLPSITNMLKEGKSPEDILNI
                     VLDGLEPKILDTCEVGFMCECSKERVKTALVAIGKKSLAQIIEEDKKAEVGCQFCNKK
                     YMYSEEELLEILKEM"
     gene            13400..14200
                     /locus_tag="PC465_002554"
     CDS             13400..14200
                     /locus_tag="PC465_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HDF2649840.1"
                     /translation="MESKTKYIGISILILLMIFLIAKNFNGKLEIPIPESNSRKFKSA
                     AVFYPQHQDDEVLWGGSAIVDAIKQCGVDNVYVVLVSDGSGVNVFKANTKFRNLTRKQ
                     KEELRNNEFKSALRELGVKPQNVIILADIDKKEGIHYELMEKTILDFEHKFKGNVTHI
                     AHHYKYDDHIMHRKNGEVLKKLKREGKIKDDLYFVKPKYVKYIPRNERAIYKAMDFDD
                     YNKVKSACYEYKVVNSKRKMYGIGYISAHSYFEHLLNDPELTSVLSED"
     gene            14727..16967
                     /locus_tag="PC465_002555"
     CDS             14727..16967
                     /locus_tag="PC465_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF2649841.1"
                     /translation="MNNEFIILKGCKENNLNNISLKIPKRKITIFTGVSGSGKSSIVF
                     ETIAKESQRQLNERFSTFVRSFLPKYGEVKADCIENLSTPIIIDQSRLGGNSRSTLGT
                     ITDVNSFLRALYSRFGSEYIGNANMFSFNNIDGMCPHCHGLGKKLVPNMNQILDMNKS
                     LNEGAILLSGFGVGSWHWNIFAESGFFDINKRICDYSEVELEKFLHGKAEKIKIENAG
                     QTNMTYEGLMVKFNRLYLSREGEISEATKKKLSKLLIEDRCPICDGRRLNERVYRSLI
                     NGYNIADLTSMQIDELAEVIKSIDEAEAQPLIKGIIEKLNSIIDIGLGYLTLDRETSS
                     LSGGESQRIKMVKYLNSNLVDLMYIFDEPSVGLHPKDVYKLNNLLKKLRDKGNTIIVV
                     EHDPDVIKIADHIVDVGPKAGKYGGEVVYEGSYENLLTSGTLTGNALSKFLPIKESVR
                     EHSGYLEVKNCNKNNLKNVSIKIPKGVLTLVTGVAGAGKSTLIKDEFLKQNPSAVLID
                     QSPVSANSRSSLATYSGIMNNIRSIFSKTNGVNASLFSSNSEGACDNCKGSGIVEMNL
                     AFMESIKSTCNVCEGKKFKKEVLEYRFQGKNIIEVLEMSVLDAIEFFNLKQIKTKLQC
                     IEKMGIGYLTLGQTLDTLSGGECQRLKLASELNKESSVYILDEPTTGLHMADIENFIS
                     IIEEIVDNGNTVIIIEHNIDVIKRADWIIELGPEGGTKGGRVIFEGIPKQLCNNKISL
                     TAKYIV"
     gene            17379..18914
                     /locus_tag="PC465_002556"
     CDS             17379..18914
                     /locus_tag="PC465_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDF2649842.1"
                     /translation="MINDILTLLSERSDFFIKLSIEHLMISIISIIIAIVLGGIIGII
                     VSEFHNSSKPILGTINFLYTIPSISMLGFLIPFSGIGNTTAVIALTIYALLPMVRNTY
                     TGITNVDKNILEAARGMGSTDFQILYKIKLPLALPVIMSGIRNMVIMTIALAGIASFI
                     GAGGLGVAIYRGITTNNTIMTITGSILIALLALIFDFILGLVEKFFQRKRKKKNRKKV
                     FAILGSLILIATIFTSYLFNPSKTQTIHIATKPMTEQYILGEMLDILIEKNTGLNVEI
                     TQGVGGGTSNIQPAMKNGEFDIYPEYTGTGWNMVLKKNELYTESMFSKLQSEYKTKLK
                     MQWTGMYGFSNSYALAVRKEVADKYNLKNITDLKDVSSKLTFGAEYDFYEREDGYTPL
                     CNTYGLNFKDTVDLDIGLKFQAINEGKIDVMPIFTTDGQYSVSDVVVLKDDKNFYPSY
                     QCGNVVRLEVLEENPELSKVFKMVGDILTDKEMAKMNYDVENNNLEPREVAREFLNKK
                     GLL"
     gene            18930..19691
                     /locus_tag="PC465_002557"
     CDS             18930..19691
                     /locus_tag="PC465_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2649843.1"
                     /translation="MTPIIQFKNIKKQYNDKTIIDNLNLDIEKGEFLTVIGSSGSGKT
                     TLLKMINGLILPDGGNILINQTDIKNEDLIKLRRRIGYCVQGSVLFPHMTVEENISYV
                     PNLLSKKNKLEVKSAVNKWMEIVGLPNDMKVRYPSELSGGQQQRVGIARALASSPEIL
                     LMDEPFGAVDEITRKQLQKEIKEIHKKTGVTIIFITHDIYEALILGTKTLVLNHGVVQ
                     QYDTPENILNTPANQFVDQLLNIRKSIIDDDNLKE"
     gene            20029..20898
                     /locus_tag="PC465_002558"
     CDS             20029..20898
                     /locus_tag="PC465_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2649844.1"
                     /translation="MDNNLITIEKTLDYIEKHLLDEMLDLNVISKEIGYSKYHLHRMF
                     TSVVGFSVHNYIQRRRLTEAARMLIFTEKPIIEIALISGYDTQRSFSRGFKKMFKRSP
                     NFFRRHQDFLPLQLKFDIHNRKKLRGDMVLDVKKVNCADINIVGYSGKVRKGFHIIGK
                     CWRDLHKNKEMIENKVDLGFLIGVSDYSNFKEIENTPTFTYIAGAQVATFGKLPNGME
                     KFVLPKSNYIVFTFIGKNEDSMQNVVEYIYQEWFPNSSCQFNENNLYDFVKYGEKTDE
                     NGLSEIQFWVPII"
     gene            21227..21478
                     /locus_tag="PC465_002559"
     CDS             21227..21478
                     /locus_tag="PC465_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HDF2649845.1"
                     /translation="MNVENELLKNLDRLHTTELGVVRIKKNLSLETNDVVNWCKTKIE
                     SPNAIINRKGKNWYISVYDCIITVNAHSYTIITAHKEKK"
     gene            21590..22369
                     /locus_tag="PC465_002560"
     CDS             21590..22369
                     /locus_tag="PC465_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2649846.1"
                     /translation="MNDTVKEKLAESLTSDTTDILPYLPYLLQDFWELGSSPEQMLQL
                     FRKHIPFNEDTKVLDLACGKGAVSVKLAKELNIHIKGIDLIPEFIDYARRKAIEYKVD
                     ALCDFEMNDANSSVKIEHDYDCVIFGAVGDILGNYKETISKLLPTIKSKGFILIDDAY
                     VVDKSTNEQLNFERVYPTYNEWCILFKELGLKLIECIPCLELENDVEEEMNWIITRAN
                     ELIKKYPSQKDMFEQYVISQKNEYTDLQQDLVGATWILQKE"
     gene            complement(22504..23154)
                     /locus_tag="PC465_002561"
     CDS             complement(22504..23154)
                     /locus_tag="PC465_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649847.1"
                     /translation="MNIVMINGSPKVNKNNSQYFLSELKQLIQNDNKVFTFKVDSTSK
                     YPDALNAILNCDRLIIAFPLYVDGIPSHLLHFLEKCEKFLKTQNKKPIPVYAIVNCGF
                     NEGEHNHLAIQMIEHWCKKINFTWVQGIGIGAGEMFGSLESVPLGKGPKKDLGIALKE
                     LSKNILSDNIHIDDSNKSTIFISPNFPRFLYKLMGNHQWNTQAKSNGLTKSDILKK"
     gene            complement(23151..23654)
                     /locus_tag="PC465_002562"
     CDS             complement(23151..23654)
                     /locus_tag="PC465_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2649848.1"
                     /translation="MRLLIHDLTDKELEKLLPKLDDNIKILSNTKEIHKCIGCFGCWI
                     KTPSECVVKDYYSNMGKLINESDGIIIISRCCYGGFSPFVKNVLDKSINYILPYFVIK
                     DNMMRHKSRYDKQINLKAIFYGDCITEAEKETATKLVNGNAINFNIKEHSVCFYENIQ
                     DIRGESI"
     gene            complement(23703..24218)
                     /locus_tag="PC465_002563"
     CDS             complement(23703..24218)
                     /locus_tag="PC465_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF2649849.1"
                     /translation="MLEYIILGFLMEKELSGYDLKQIMSESTSYFFDASFGSIYPALK
                     RLETKGYIHYHEVIDGSKLKKLYSITNTGKEVFLEWLKKPINFSKTKQDHLVNIFFYK
                     YLPKEIIETNLKMLITEVELLLNKLSKQKNDAEENHCVDQYTYMYATMIYGVDYYNFV
                     INWCKDLLKNL"
     gene            24498..25025
                     /locus_tag="PC465_002564"
     CDS             24498..25025
                     /locus_tag="PC465_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2649850.1"
                     /translation="MHEQIDYCERKKIRTINIKGENMRELLKWVSIINRYNTNYIDRK
                     LADIGINNSQYFYVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGV
                     KDKRTWHLYPTEKSLECYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLAIDM
                     NEEAKLEAKENGRKI"
     gene            25009..26412
                     /locus_tag="PC465_002565"
     CDS             25009..26412
                     /locus_tag="PC465_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2649851.1"
                     /translation="MEEKYKEPLEYEKVSKLLTKYAIPSIIAMLVSALYNIVDQIFIG
                     QGVGVLGNAATNVTFPLTTICTAIALLLGIGGASKCSLELGAKNSEKATKAAGNSICL
                     MAVFGISLFIVVSIFLTPLLKFFGSTSEILPYAHTYTKITSIGLPFLIMSTGMSKLIL
                     ADGRPKASMFCMLIGAVINTILNPLFIFIFNMGIAGSALATVIGQLISFGISVHYIKN
                     FQHIKLHKKSFKLDSIIYKHIFALGSSSCFNQLAMTVTQIVMNNTLAYYGARSVYGSE
                     IPLACVGIIIKVNMIFISIIIGISQGMQPIIGYNYGAEKYNRVKEAYKFAVGSATIIS
                     VIAFLCFQFFPRQITSIFGNGNETYFIFAEHYFRTFLFLTFINGVQIVSSTFFTSIGK
                     SVLGLFTSLTRQILFLIPLIVILPMFMGIDGVMFAGPIADAAAAMVCIYFAVHEMKSL
                     TIKQNNLMSNHNKIAEV"
     gene            complement(26706..27017)
                     /locus_tag="PC465_002566"
     CDS             complement(26706..27017)
                     /locus_tag="PC465_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649852.1"
                     /translation="MKKIIKSFTSWFFLIALFEIYMHQIGQDSKSIVLIGLNPILSII
                     SRVDSFFVFMDSGMQIPCRTITGSISIYWYIASILSFLIYGIILDLIRIVISKIGNKT
                     K"
     gene            complement(27073..27666)
                     /locus_tag="PC465_002567"
     CDS             complement(27073..27666)
                     /locus_tag="PC465_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2649853.1"
                     /translation="MISDSISKRRSIRKYKNQSISHETIEKIIEAGINAPSSKNRQPW
                     RFVVITEKEKESMLKAMSKGIQNEINDNGLLPGSRQHIAGANYTVEIMKQAPVTIFIL
                     NILGKSPLEKLSPEERFYEMANMQSIGAAIQNMSLTAVELGLGSLWICDVYFAYRELC
                     EWLNTDSQLVAAISLGYPDEEPSRRPRLQLSDVTEWR"
BASE COUNT        10329 a         3449 c         4549 g         9562 t
ORIGIN      
        1 ggataatatt taataggttt atatgatgaa aagattataa aataataaac aatatgattc
       61 catataccaa taaataggat aatatttaat aggtttatat gatgaagaga ttataaaata
      121 ataaacaata taattccata taccaataaa taagataatc tttaagaaaa atgattatat
      181 ttaaaaggta agcataaaat ttataaactt ttagaataga aatctcaatc aattagatat
      241 tcaaattgat gaatatgaat acctaaatag attgagattt attatgtaca aaacttatcc
      301 tagtatatct gacattttat aaagtccaga ttgcttacca attaaaaatt tagctgcaac
      361 tatagaaccg tttgcaaata cttcatcaga ttgagaatga tggcttaatg taagaacttc
      421 attatcacct gcaaatataa catcatggtc gctgattata ttgccacctc ttatagagtg
      481 tattccaatt tcatttggtt ttcttttaca atctctacca tatctaccat gtgtattttc
      541 actttcaggc aagacttctc taattgcatt agctatcata gtagcagttc cactaggggc
      601 atcttctttt ctattgtgat gtttttctat gatttcaata tcaaaacctt ctaacatctt
      661 tgaagcatcc ttaactaatt ttattaatat atttactcca agagatgtat ttgatgataa
      721 taatatagga atgttttttg atgcttcttc tattttattt aagtcatttt cgtcatatcc
      781 agtagtagct aatactacag gtgtattatt ttttagagca tatgacaata ttggctctaa
      841 agtctcatga tgtgaaaagt ctattatgac atcagttttt tcagttacat cagtcattgt
      901 tttgtaaagc tttgtatcac tatgatgacc tttttcatca gcagacctag ctacaccaca
      961 aaccaactct aattcattat ctttttttac acattctgct aaaactcttc ccattgttcc
     1021 attatagcca ctaattataa ctttcaacat aaattcctcc tatgaaatta ataaaaattt
     1081 gttatatttc tataagttta ttttatcact aatataattt atataaaata atattagtga
     1141 taataagctt acaatttatc ttacattaaa aaatttaagt ggatttttca aaatatagat
     1201 aaatttcttt ttcattgttt aaatgataaa aatatatttg acttcatacc aaaaagagtg
     1261 ccccatgaac taaaaagtta attttgaaat accatattca tatatcatat gatttatttg
     1321 gaaatcaata ttaatacatt aaaataacta aatacatgta tgcataaaga tgtataaaaa
     1381 atatataaac atatagtatt aattttaaat tcaacaattt aattgttaaa agtgttatta
     1441 ttaaattaga gatatcttaa cttaatatac tgagatggga gtgatagata tgttaaaaga
     1501 agaaaaaact tatcaagaga aagacgcaaa agtattcaat ggagtggcag ctttgataat
     1561 gattttatta tttttagtag tttcaatagg tatcatggtt tttgggatag taaaacttga
     1621 tagtggattt actggaatag gttcacttat gttaattttg ggacttgtat ttatagtagt
     1681 agattttatc ctattttttg ggctaagaat gattaatcct aaagaagcta tagttctagt
     1741 tttgtttggt aactattatg gaactataaa aaaagaaggg tactattggg tgaatccatt
     1801 ttgttcagca ataaacccag cagtatcaag aattaatgta tcgaaatctt catctgatga
     1861 aaaggtagat atatcaacta attcaagggg caaaaaagta tctttaaaaa caatgactct
     1921 taataatgaa aagcagaaag tcaatgattt attgggaaat ccaattataa taggagtggt
     1981 tgtaatttgg aaggttatag atgcaacaaa ggcagtattt aatgtggata attataatac
     2041 attcttatct attcagtgtg attctactat tcgcaatgtt tcaagacttt atccatatga
     2101 tgtatctgaa gatggagatg aaaaatctct tcgtggtagt agtcaggaaa tagcagatag
     2161 attaaaagat gaattacaat caagggttga cattgcagga attgaagtgt gtgaagtgag
     2221 aattactcat ctttcttatg caccagagat tgcagcagca atgttacaac gtcaacaagc
     2281 agaggctata atagcagcac gtaaaaagat tgttgagggg gctgtaagta tggtagagat
     2341 ggcattgact aatttaagtg aaaataatgt tgtgactttg gacgaagaac gtaaagcagc
     2401 tatggtaagt aatctgttag ttgtgctttg tggcaataaa gatgcacaac cagtagtaaa
     2461 cagcagttct atttattaaa ttataaaaag tttaatagtt tattttattg atatatagaa
     2521 aatttagtag ttcattttat taaattatag aaagattaat ggttttcact ttattaaatt
     2581 ataaaaagtt taatagttta ttacattgat atattgaaaa attgaaggaa ataaaaatac
     2641 ttgtcagcaa gaaataaaaa tgatataaga atgaataaga gaattgtaaa aaaataaaat
     2701 gattataaat aaaagataaa aatattgtaa aaaagagggt gcctctggtg aattaaattc
     2761 acacagagac acctttttaa ttaatttttt aaattagtat attattgttt aattaatagt
     2821 atagtactat ttaattagtc taaatttcta aggtcttcca taagcttagt tttgtcagcc
     2881 gttttttcat ctttcatttt tataacttta gcaggagaac cagcaacaac agcaccagct
     2941 tctacatcag tagttacaac agcaccagct gcaacaacag cacctttacc gattctaaca
     3001 ccttcaagaa taactgcatt agctcctatt aaaacatcat cttcaactat aacaggagta
     3061 gcagaaggtg gctctaaaac accagcaaca acagcaccag cacctaagtg aacattttta
     3121 ccaagagttc ctctagctcc aataacagca ttcatatcta ccatagaacc ttcaccaata
     3181 acagctccta tatttataac agctcccatc attacaacag catttttttc tatagtaacc
     3241 atgtctctta ttattgcacc tggctcaatt cttgcatgtt cacttaaagt attttttaga
     3301 ggaatagcag aatttcttct atcatattct acatgagtat ctgttatatc atttccatgt
     3361 ttatctaata cttccattat atcatcatag tcacctacaa atatataaga accattattt
     3421 ccaaatacct taaatttatc agttgattgg aagtgtaaag agttagtatt tacatatacc
     3481 ttaacaggtg ttttcttttt aacttctttt atataccttg ctatttcata agcatcgttt
     3541 aaatttacca tttgttaatt ctccttgtat ttcattatat ttcttttatt atatacttat
     3601 ttgtcaattt tagtatatac ttacttctta ttatttatat tttattttag ttagttttta
     3661 ttgtatagac atagtattaa ataaatttat tatatatgtt tgatttgtat tgcatattat
     3721 tatatatata ttgtatatgt ttaatttata ttgtgtatta ttatatttat actattatcc
     3781 caacatgctg tccatattat aaaatcctgg tttttgctta actaagtatt tggcagcagc
     3841 tatagaacca cttgcaaaga taccacgaga ttgagcttga tggcttattg taagaacctc
     3901 attgtctcca gcaaatagag catcatgttc gccaacaata tttccacctc ttatagcatg
     3961 aataccaact tcatttggtt gtctttttgc actacgacca tatctaccat aattattttc
     4021 aacgtttggc aaaacctctt ttatagcgtt agcaatcata acagctgtgc cacttggggc
     4081 atctactttt ctgttgtgat gtttttctat tatttctata tcaaatcctt ctagtaattt
     4141 agctgcatct ttaaccaatt ttactaatac atttacacca agagacatat tatatgattg
     4201 gaatacagga ataactttag ccgcttcacg tattttgttc atttcgtcat cattatatcc
     4261 agtagtagca attactaaag gtgttttagt ctttaaaacg taagataaga tattatctaa
     4321 attagagtga tgagaaaaat ctataactac atcagcttcc tcaactatag tactcatatc
     4381 ttcataaatt ttaaggtcgc cttcatagct atccagacct ctagctgcaa cacaaaccaa
     4441 ttctaattca ttatcttctc ttatagtatc ggctaaaatc ttacccattt ttccatcata
     4501 accagttgct ataactttta acataatttc ctcctatgat taagggctaa cttttgacca
     4561 aacttacttt ttaccatgca ttaatcttta ctatgcatta acttttagcc caaagttaac
     4621 taattctttc tttaatactt ctaaatttgc tgggtccatt tctgctagag gtaatcttaa
     4681 atctccaaca ttgaatccca ataaattcat tgcagtctta actggtatag gatttacttc
     4741 tataaataaa gctgcgatta gagcatccat accaagttgt aattttctag aaccttcaat
     4801 atcgccttca aagaatttag ctaccaaatc gtgagtttct tgagggcaaa cattagcaag
     4861 tactgatata actccttgac ctcctaaaga taataaagga agtatagtat catcattacc
     4921 agagtagata gcaaagtcat ctggaactaa actagctatt tctgcaacct gtcctaggtc
     4981 tccactagct tcttttacag caactatgtt atcaatttta gcaagttcaa ctataaggct
     5041 aggacttata tttacacaag ttcttccagg gacattgtaa agtataattg gaagtttaac
     5101 actgttagct attgtttcaa aatgacgctt aagtccagct ttattagctt tattgtaata
     5161 aggtgttatt attaatagag catctactcc taatttttca gcttcttgac ttaagttaac
     5221 tgagtgcata gtatcattag aaccacttcc agctataaca ggaactcttt tattaacttt
     5281 ttcaacaaca tacttaatag tagcaagttg ttcttcatca gtcatagtat tagcttcacc
     5341 agtagtacca caagatacta tagcatcagt accattagct atttggtatt caactaattc
     5401 acctaatttg tcaaaatcaa ctttgttatc ctttgtaaat ggtgtaacta gagcaacagc
     5461 agaaccttta aatatcatat aaaatcaatc ccctcttttt tatttttgtg ttttatatta
     5521 cagttacttc taatgcttgt ttttgagtta ctattaatat tttacaaaat tatatattta
     5581 tacaagtttg tatattatac taaatcgtat gataaagcca tttcagctat ttgaattgcg
     5641 ttagttgcag caccttttct tatattatca gcaacaaccc aaagatttac accattatca
     5701 acactaaaat ctcttcttat tcttccaaca aatacttcat ctctatcatc aaattctaca
     5761 gcagttggat attcgttttt agcaggatta tcaactacta caacacctgg agcttcttca
     5821 agtgttttta ctaaatcatc taactcaaat ggattgttaa actcaacatt tatagattca
     5881 ctatgaccat tttttactgg aactcttaca gtagttgcag ttatttttaa atcgtagtta
     5941 tcaagtattt tcatagtttc atttaccatt ttcatttctt ctttagtgta tccattttca
     6001 gtgaatgaat ctatatgagg aagacagttg taagaaattt gatgagggta gaatccagta
     6061 ggattaccgt tcattccttt ctctaaatct tcaacacctt taacaccaga accagataca
     6121 gcttggtaag tagagtaaac aactctctta attttgtatt tatcatcaag agctttaaga
     6181 ggaaccatag cttgtatagt agagcagtta ggattagcta ttataccctt atgatttttt
     6241 atggcttctg gattaacctc aggaactact aaaggcacat ctggattcat tctccattga
     6301 ctagagttat ctactactaa gattccattt gaagcagcta ttggagcata cttttcacta
     6361 atacttccac cagcagagaa taatgctatt tgtatgcctc tatcagtaaa tgaagtttcc
     6421 tttaattctt ctactatata ttctttacca caaaacatta ctttagaacc agctgattta
     6481 gaagaagaga ataaaaatag attttctatt ggaaaatttc tttcttctaa tacttttaaa
     6541 aatgttctac ctaccattcc agtagcacca actattgcta catttacttt tttcatataa
     6601 attcacccca attttaaatt attaaaacat tattttattt tagttataca agtaagatat
     6661 gttaatattt ttatatatcc aaaaacttta atattatatt aacaacttta attatataca
     6721 aaaaacgtac aaaggtatac tttgtacgtc taatttatca ctcaaagtaa accctgtagc
     6781 tcatcaccta caaaaataag tgacagtatt acacatgtta tgtgcaatcc cagaaaatat
     6841 tattgcaaga aatattttct tcggctgtaa atcctttttc caatcattaa cacctgccag
     6901 ctactattgg atactcttag ttacagctac ctctacccta ggttaatagg atattaaaat
     6961 ttgattattc taataataat acatatttaa gaaaaaatca acttatttat ataaatattg
     7021 ctaaaattta aatccaaaat ttgtcaattc ttgttttaac acattaagat tagtttcttc
     7081 catttcagct agaggaagtc ttaaatcacc aacattaaaa cctaaaatgt tcatggcagt
     7141 tttaacagga actggattta cttctataaa taaggcagca attaaagcat ccatatcaag
     7201 ttgtaatttt tttgagcctt caatatcacc ttcaaagaat ttagttacta aatcatgtgt
     7261 ttctttagga catatgttag caagtacaga gataacacca cttccaccta atgataatag
     7321 tggtagtata gtatcatcat taccggagta tatagcaaag tctttaggta ctaatttagc
     7381 tatttctgca acttgagcta agtctccact tgcttccttc acagcaacta tattatctat
     7441 tttagcaagt tcagccacaa cagatggctt tatattcact ttagttcttc ctggtacgtt
     7501 gtataaaata attggcaact taacgctatt tgctattgtt tcaaagtgaa gtttaagacc
     7561 tttctcatta gtcttattat agtaaggagt tattattaaa agaccatcca cccctaattt
     7621 ttcagcttct tgactcatat gaacagacaa catagtattg tttgaaccag tacctgctat
     7681 aacaggtatt ctcttattaa ctttttcaac tgtatatttt attacagcaa aaatttcaga
     7741 ttcactcata gtagtcgcct cacctgttgt tccacaaaca actagtgcat ctgtgccatt
     7801 ctcaatgtga tattcgatta attcacctaa tttttcaaag ttgacattat tatcctctgt
     7861 aaatggggta actaaagcaa cagcagaacc tttaaataac atataatcaa atctcctttt
     7921 ttatctaaat ttaatttttt aagtacaata ataattatag tacaaattaa ttaattttaa
     7981 taggtatagt taatatctta actgtttaaa taagatattt atattatatt aatattagaa
     8041 aaattttaaa taaatgtttt attctcaaaa tatgcatatt aatttaataa aatataccaa
     8101 aatggaaata aaaaataaat tttatgagaa tttaataact aataattaat atatttaggt
     8161 tataataaat atgtgcgtaa aatctaacaa taagcaataa taccgtaaat ttaggaggaa
     8221 taatatggat actttaaagg aactttttaa aataggaagt ggaccttcaa gttctcatac
     8281 tatgggacca caaagagcag cagagagatt taagaatgaa aacccagatg cagaaagttt
     8341 tagagcaata ttatatggta gtttggcagc tacagggaaa ggtcacttaa ctgactatat
     8401 aattgaaaaa actatagcac ctaaaaaagt cgaaattgtt tgggaagaag atattataaa
     8461 agattttcac ccaaatggga tgaagtttga agctttagat aaagataaaa atgtaacagc
     8521 tgaatggact gtatattctg taggtggagg gactatagca gaagaaggtc aaagaaacag
     8581 taaaagcaat agtatatatc acttagatac tatggatgag atagtaaaat ggtgcaaaga
     8641 aaataataag actttggtag attttgtgtt ggaatgtgaa ccaaaagaca taaaagatta
     8701 tataaaaact ataaaagatg ctatgagaaa atctattgat gatggactaa gtacagatga
     8761 aataatacca ggcaagttat tattaaaaag aagagcaagt acattttata atgcatataa
     8821 aaaagataag agcttctcaa cacttgtata tgcatatgca ctagcagctt cagagcaaaa
     8881 cgcttctggt aatataatag ttacagcacc aacttgtggt tctgctggag taataccagg
     8941 aatattcttt gcaatgcagg atttctataa ttatgatgac gaaaaaataa ttgaagcact
     9001 acttgtagct ggaataatag gtaatataat aaaaactaac gcttcaatat ctggagcaga
     9061 ggtagggtgt caaggtgaag ttggagccgc ttgttctatg gcagcagcag cagtagcata
     9121 cttaaaaggt ggaactatag accatattga atatgcggca gaaatagcac ttgaacatca
     9181 tttaggaatg acttgtgacc ctgtatatgg atatgttcaa attccatgta tagaaagaaa
     9241 tgcaatggca gctcaaagag cttatgatgc agctaattat gcattactaa ctgatggctc
     9301 acattctgtc tccttagacc aagttgttga aacaatgaaa gaaactggta tagatatgat
     9361 ggataagtac aaagaaacag ctaagggtgg acttgctaaa catttcttct cttgctaaaa
     9421 ataaaatttt ccaataataa ttcctctgtt ttgatttatg aaacagggga attattatta
     9481 atggtgaatt atttaataat gcaaaatatt tttatattca atttagcttt ttatttttaa
     9541 ttagtataac atgctatata atattttaat tataaagaaa tatagaaata ttttttaata
     9601 aattagaaat tggaggagat tacatgagag aggcatcata tttacaagaa caactttata
     9661 aacataggaa gtcattaaat cctattgcag agattgggag aaaagagtat aagacttcaa
     9721 aatatataag agattatctt gataaattag gaattgagta tgaagtttat ttagaaacag
     9781 gtatagtagg tgtaatagaa ggtaaaagac ctaaaaaaga tattgctttt agagctgaca
     9841 tagatggtct tcatagtgaa gaaggggtaa aacatttatg tggtcatgat ggacatgcta
     9901 ctatattact tggattaatt gagtatttaa atgataataa agaagactta aatgataata
     9961 tagtatttat attccaacca gcagaagaag gtcctggggg agcaaaagct ttaatagatg
    10021 aaggagtgct tagaaaatac aatattgatg aaatatatgg gcttcatata tatccagagt
    10081 taccagaagg ttatgtaggt acaagagagg gctattttat ggctcaaata ggagatattg
    10141 acatagaaat agtgtctaaa agtggacatg gggctatgcc acaaaatggt attgatggta
    10201 tagtgatagc ttcaaacttt gtaagctcac ttcaaactat agtgtctaga aatataagcc
    10261 caatagacaa tgcagtgttg actattggta gaattgaagg gggagctaga agaaatataa
    10321 tagctgaaaa tataaagatg gaaggtacta tgagatgttt cagcccagaa gtgtatgaga
    10381 aaatgaagct tagagttaga gaacttgcta gagggtttga attggcttat aactgtaagg
    10441 ttaatataaa tattatagat gattatattg ctgttaaaaa tgacaaggat ttgtatcaag
    10501 agtttgtaga ggctattgga agtgatactg ttgtagagtt agagccactt atgatatcag
    10561 aagatttttc ttattatcaa aaagaagttc caggattatt ttttatgttg ggttcaagaa
    10621 acgaagaaaa aggatttgta aatggtcttc ataatataaa ctttaatttt gatgaaaaga
    10681 tatgtgtaaa tgcattgaat gtttattcaa aattattaaa atacaaagaa gcaatagatt
    10741 aggaaaataa attataaaga ttaaaaagca taaataccta aatttaaaaa aagtgtatta
    10801 ataaataccc cttacatatt tgtataaatt tattttaatt gacaaaaata caaataagaa
    10861 ggggtgattt ttttgaaaga aaaagtacaa agagaaaaga agataactaa tggcaagaat
    10921 actaaaatat tgacaaatga tgatataatg aaatatgaga tagcctcaga actaggtctt
    10981 atggataaag ttggtgaacg tggatgggca ggacttacag ctaaggaagc aggaagaatt
    11041 ggaggtatgc ttacatcacg caaaaagagg cttaaaaaga ttgtggagga gcagaataaa
    11101 aaggatgagt caatatagtg attttgcgtt tgtatatgat gaacttatga atgaagttga
    11161 ttataatggt tgggttaaat atatagaaga tataatagat agtgaaggtg taaaagtaaa
    11221 aaatatattg gaattggcat gtggtacggg taatcttaca attccattgg ctaaaaaaaa
    11281 ttacgatata gctggtatag atatatctga tgagatgctt agtgtagcaa gagaaaaggc
    11341 agaaaaagaa ggagtagaat tagttttact tcaacaagat atatcagagc ttgattttga
    11401 aatatctgat ttggactgtg tactttgtgc ttgtgatgga tttaattata taacttatga
    11461 tgatgatttg gaaaatgtat tttcaaagac atatgaatta ttaaagaaag atggaatatt
    11521 catatttgat ataagttctt tttataaatt agccaacata ttgggaaata acatgtatgg
    11581 agaaaataga gaagatatag cgtatatgtg gcaaaattac tttgatgaag aagagaatct
    11641 aattgaaatg gaacttacat tctttattaa agatgaatgt ggaaagtttg aaagatttga
    11701 agagatacac caacaaagag catatactga agatgagata gttgatatgc ttgaaaaatc
    11761 tggatttaag gatataaaat attatgggga ttttacattt gacaaaccta gtgaagaaag
    11821 tcaaagaatc ttctttgtat gtaaaaaata agatattctt gactatataa gataattatt
    11881 aaaaataacc atgatataaa aatatagaaa atgcagtttt atagattaaa agtaaagtga
    11941 tgatacttta tgacttttat tttttaataa ttataaagtt ctatagataa aaattaaaat
    12001 atagtaacta ttacttagta aaattaaaat aaaatgggtt ttgcccaagg ttaagataga
    12061 taagtattta tagataaatt aaggtagtaa tataataaaa ataagacaat taacgggaca
    12121 tggaggaata ttaatgagag attatgtact aagagcgaca tcaggaaatg gtcaagttag
    12181 agcatttgtc gcaactacta gaaatacagt agaagaagct agaagattac atgaaactac
    12241 aaaagtagca acagcagcac ttggaagaac attaacagcc acatctataa tgggattaat
    12301 gatgaaaaat gatagtgata aattgactgt aataataaaa ggtggaggtc caattggaac
    12361 tattatcgcc acatcagact ctaagggaat ggtaaaagga tatgtaggaa atccacaagt
    12421 agaggttgaa gactatccaa atggaaagtt aaatgtagca gcagcagtag gtacagaagg
    12481 tgttgtaaaa gttataaaag acttaggtct tagagaacca tataatggga cttatccatt
    12541 ggtaagtgga gaaattgcag aagactttac ttattatttt gctgtatcag agcagactcc
    12601 atcagtagta gctttaggtg ttcttacaaa agaagatgaa gtagagtttg ctggaggatt
    12661 tatagttcaa ttaatgccag atgcagaaga agagactatt gctaagttag aggaaaatgt
    12721 agctaaatta ccttctataa ctaacatgtt aaaagaagga aaatcaccag aggatatatt
    12781 aaatattgtt ttggatggtt tggaacctaa aatacttgat acctgtgaag ttgggtttat
    12841 gtgtgaatgt tcaaaagaaa gagtaaaaac tgctttggtt gcaattggta aaaaatcatt
    12901 ggctcaaata atagaagaag ataaaaaagc agaagttggt tgccagttct gtaataagaa
    12961 gtatatgtat agtgaagaag agttgcttga aattttaaag gaaatgtaga ctataaaaat
    13021 agttgtattg atataagtaa tgttatagta atatagtaaa gtcgtattga tatagtaatt
    13081 aaagtataat ttattaataa tagacatatt tatattaaaa aataagttta ataaattttt
    13141 aagcttaata aattttaaga attaagaagc tttctggctg taatgtttgc aatgttgcag
    13201 ttagaaggct tttttatttt attatagttc gtgtcaaaga ttgtatgaaa caataaaata
    13261 ttgtaaaata atttgtatat ttagacttga tttacacaaa ggtttataag atatttgagt
    13321 tgattatacg aaattctatg aagtagtaac cctgtgactt taatcatggg aggttcagaa
    13381 gaaggagaaa attttaaata tggaaagtaa aacgaagtac ataggaataa gtatattaat
    13441 attattgatg atatttttaa ttgcaaagaa ttttaacgga aaacttgaaa tacctattcc
    13501 tgagagtaat agtagaaaat ttaaatcagc agcagtgttt tatcctcaac atcaagatga
    13561 tgaggtttta tggggaggaa gtgccattgt agatgctata aaacagtgtg gtgttgataa
    13621 tgtatatgtg gtattagtat cagatggttc tggagttaac gttttcaaag ctaacacaaa
    13681 atttagaaat ttaactagga agcaaaagga agaacttaga aataacgagt ttaaatcagc
    13741 tttgagagag cttggagtga aacctcaaaa tgtgattata cttgcagata tagataaaaa
    13801 ggaaggcata cattatgaat taatggaaaa gactatattg gattttgaac ataagtttaa
    13861 aggcaatgtg acccatatag cccatcacta taagtatgat gaccatataa tgcatagaaa
    13921 gaatggggaa gttttaaaga aacttaaacg tgaaggtaag ataaaagatg acttgtattt
    13981 tgttaagcca aaatatgtaa agtatatacc aagaaatgaa agagctatct ataaagcaat
    14041 ggattttgat gactacaata aggttaagag tgcttgttat gaatataagg ttgtaaattc
    14101 aaagcgtaaa atgtatggta taggatatat ttcggcacat agttattttg aacatcttct
    14161 aaatgaccct gaacttacgt ctgtattaag tgaagattaa tttcttataa gtagtaagtt
    14221 atgtttgata agttgattgg aattttctat agttttgaag gtattggaaa tttagtttta
    14281 tttaaagatt taaagataga ggtttttagt gtttaaaatt ttaaagttaa gttgagtaat
    14341 tgtatagaat tatttgtgaa agaagaaaca gtgtaaaaca tagtatctta tttatggttt
    14401 taaaatcata ggcaagatac tttttttatg taactaatac cattttgaga ttattaactt
    14461 aagaatttta tataatttaa cactcatata taatgatgat atttaggtag aatagatgca
    14521 attacgctta aataaaataa ctgtattttt tataaaaatc aaaccctaca ctatactacc
    14581 agataaaatc tacatgctat aatttgacct gtgtttataa aaaaaggagt aatctaataa
    14641 aatagtattt cacttatgta taactaacaa ctattattac gattttctct aaataattta
    14701 aagaaaaata atgcaggagg taaaatatga acaatgaatt tataatttta aaaggttgca
    14761 aagagaacaa tttgaacaat atttccttaa aaataccaaa aagaaaaata accatattca
    14821 caggggtgtc gggttctgga aagtcatcta ttgtatttga gacaattgca aaagaatcac
    14881 aacgccaact aaatgaaagg tttagtacat ttgtaagaag ttttttacct aagtatggag
    14941 aggttaaagc tgattgtata gaaaatttgt caacaccaat tatcatagac caaagtagac
    15001 ttggtggaaa ttcaaggtca accctaggta ctattacaga tgtaaattcc tttttaagag
    15061 ctttatattc aaggtttggt agtgagtata taggtaatgc caatatgttt tcttttaata
    15121 atattgatgg tatgtgccca cactgtcatg ggcttggaaa aaagctagtt cctaatatga
    15181 accaaattct tgatatgaat aaatcattaa atgaaggtgc tatattgctt tcagggtttg
    15241 gagtgggttc ttggcattgg aatatattcg ctgaatcagg attttttgat attaataaga
    15301 ggatatgtga ttattcagaa gtagaattgg aaaagttttt gcatggtaaa gcagaaaaga
    15361 ttaagataga aaatgctggt caaactaaca tgacatatga gggactaatg gttaaattta
    15421 atcgcctata cttaagtaga gagggagaaa tatctgaagc tactaagaaa aaattgagta
    15481 aacttcttat agaagataga tgtcctatat gtgatggaag aagacttaat gaaagagtat
    15541 ataggtcttt aattaatggt tataatatag cagatttaac tagtatgcaa attgatgaat
    15601 tggctgaagt tattaaaagt atagatgagg cagaagcaca acctttaatt aaaggaataa
    15661 tagaaaagtt aaacagtatc atagatatag gtcttggata tttaacactg gatagagaga
    15721 catcttctct atcaggaggg gaatctcagc gtataaagat ggttaagtat ttaaatagta
    15781 atcttgtaga tttaatgtat atttttgatg aaccaagtgt aggacttcat ccaaaagatg
    15841 tgtataaatt aaataatctt ttaaaaaaat tgcgtgataa agggaataca attatagttg
    15901 ttgaacatga cccagatgtt attaagattg cagaccatat tgtagatgta ggaccaaagg
    15961 caggtaagta tggtggagaa gttgtgtatg aaggcagtta tgaaaatcta cttacaagtg
    16021 gtactttgac agggaatgct ttaagtaaat ttcttcctat taaagaaagt gtaagagaac
    16081 atagtggata tttagaagtt aaaaattgta ataaaaacaa tttaaaaaat gtatcgatta
    16141 agatacctaa aggtgtattg actttagtta ctggagtagc aggagcaggt aaaagtacgt
    16201 tgattaagga tgaattttta aagcaaaatc ctagtgctgt acttatagac caaagccctg
    16261 tttcagcaaa ttcaaggtcg agtttggcaa catatagtgg aattatgaac aacataagaa
    16321 gcatattttc aaaaacaaat ggcgtaaatg cttctttatt cagttcaaat tcagaaggag
    16381 cttgtgataa ctgtaagggt tctggaatag tagaaatgaa tcttgctttt atggagagta
    16441 taaagagtac ctgcaatgtt tgtgaaggta aaaaatttaa aaaagaagtt ttagaatata
    16501 ggtttcaagg gaagaatata attgaagttc ttgaaatgtc tgttttagac gcaattgagt
    16561 tttttaattt aaaacagatt aaaacgaaat tacaatgtat tgaaaaaatg ggtattggat
    16621 accttacttt aggacaaact cttgatactt tgtctggagg agagtgtcaa agattaaagc
    16681 ttgctagtga attaaataag gaaagttcag tgtatatatt agatgaacca acaacaggtc
    16741 ttcatatggc tgatattgag aattttataa gtataattga agagattgta gataatggaa
    16801 atacggtcat aataattgaa cacaatatag atgtaattaa aagagctgat tggattattg
    16861 agctgggacc tgaaggagga acaaaaggcg ggagagtaat atttgaaggt attccaaaac
    16921 aattatgtaa caataaaata tcattaacag caaaatatat agtataataa ataaaatata
    16981 ataaaattat aatgatattt taataaatat aatgggtata taaaatgata attaaactta
    17041 acagtaataa ataatgtgag aaatattcaa atttaattaa ataaagtgtc agaaatttgt
    17101 ttaaatttta gtattttaac ggttctgacc ttttttctta tttttatgga gaatatcgag
    17161 gatggagtct ctaatagtta cttttttgtg tctacttgca agtttgatta aaaaatggct
    17221 atacacactt gtgacttcag tcatgggagg ttccgattat aatcttaata taatttgtga
    17281 aataatttga tgacgatttg ctgatgtata aacaataaag attaactaca ttaaaattta
    17341 aatcttgtta agtaaaactt ataaaaggag agagatggat gataaatgat attctaacct
    17401 tattatctga aagaagtgat ttttttataa agctatccat agaacatttg atgatttcta
    17461 ttatttctat aataattgcg attgttttgg gtggtataat tggtattatt gtaagtgaat
    17521 ttcataattc ttctaaacct atattgggaa ctatcaattt tctatacacc attccatcta
    17581 tttctatgct aggatttctg ataccatttt ccggaattgg aaatactact gctgttattg
    17641 cacttaccat ttatgcatta ttgccaatgg ttagaaatac atatactgga attactaatg
    17701 tggataaaaa tattcttgaa gcagctaggg gaatgggaag tacagatttt cagatattgt
    17761 ataaaataaa acttccgtta gccctacctg ttattatgtc tggtattaga aatatggtga
    17821 ttatgacaat tgcattagct ggtatcgctt catttatagg tgctggaggc ctaggtgtag
    17881 ccatatatag aggaatcacg acaaataaca caataatgac aattactgga agtatactta
    17941 ttgctctatt agctttaata tttgatttta ttttagggct ggtagaaaaa ttttttcaac
    18001 gaaaaagaaa aaagaaaaat agaaaaaaag tttttgccat tctaggaagc cttattctta
    18061 tagcaactat ctttacgtct tatttattta atccttcaaa gactcaaact attcatattg
    18121 ctactaaacc tatgactgaa caatatattc ttggtgagat gttggatatt ttaattgaaa
    18181 aaaacacagg tctaaacgtg gaaattacac aaggtgtagg agggggaaca tctaatatcc
    18241 agccagctat gaagaatgga gaatttgaca tttatccaga gtatacaggt acaggctgga
    18301 atatggtact taagaaaaat gaattatata ctgaaagtat gtttagtaaa ctacagtcgg
    18361 aatacaaaac taaacttaaa atgcaatgga ctggtatgta tggtttttct aatagctatg
    18421 cattagcagt tagaaaagaa gttgcagata aatacaattt aaaaaatata acggacttaa
    18481 aagatgtatc ttctaaattg acatttggag ctgaatatga cttttatgag agagaggatg
    18541 gatatactcc attgtgtaat acatatggac tgaactttaa agatacagtt gatttagata
    18601 ttggattaaa attccaagct atcaatgaag gtaagattga cgtaatgcct atatttacaa
    18661 ctgatggtca gtatagtgtt tcagatgttg tagttctaaa agatgataaa aatttctacc
    18721 catcttatca atgtggaaat gttgttcgtt tggaagtatt agaggaaaat ccagaactat
    18781 caaaggtatt taagatggtt ggagatattt tgactgataa agaaatggct aaaatgaatt
    18841 atgacgtaga aaacaacaat ttagaaccta gagaagttgc tcgtgagttt ctgaataaga
    18901 aaggtctttt ataaattgga ggaaatataa tgacacctat tatacaattt aaaaatatta
    18961 aaaaacaata taatgataaa actataatag ataatcttaa tttagatata gaaaaaggag
    19021 agtttttgac tgtaattggt tcatctggtt ctggtaagac aacactctta aaaatgatta
    19081 atggtctgat tttgccagat ggaggaaata ttttgataaa ccaaacagat atcaaaaacg
    19141 aggacttaat taaattaaga agaagaatag gatattgtgt acagggaagt gttctttttc
    19201 ctcatatgac tgttgaagaa aatatttcat atgtaccaaa tctcctaagt aaaaagaata
    19261 aattagaagt aaaaagtgct gtaaacaaat ggatggaaat agtgggattg ccaaatgata
    19321 tgaaagtgcg ttacccatca gaattgtcag gtggtcagca acaacgtgta gggattgcaa
    19381 gagctttagc ttcttctcca gaaattttat taatggatga accttttggt gcagttgatg
    19441 agattacacg aaagcaatta caaaaagaga taaaagaaat tcataaaaaa acaggagtta
    19501 cgattatctt tattacgcat gatatttatg aagctttgat tttgggaaca aagactttgg
    19561 tattaaatca tggagttgtt caacagtatg atactcctga gaatatttta aatactcctg
    19621 ctaaccaatt tgtagaccag ttattgaata taagaaaatc tataatagat gatgataatt
    19681 taaaagaata aatttaaatt taaaatcaaa ttgttgtgat aaaaactatt gatttagagc
    19741 taacttcaag ttgtatactt gaagtggaaa agttagatta aggtatagaa gggaatttag
    19801 cagttggctg tagacaaggt aactgctgaa ggtgatttca ataaatggct agaacctgta
    19861 tctgttgaag attataataa attgaaataa gaagctcaat atacagagta gataggcact
    19921 tcaaatagaa gtgtcttttg tgtgccataa aataaatcaa aatattagca aagaatgtga
    19981 aaaacaaaat aaaataatat gctatcttta aaataggagg ggtgctatat ggataacaat
    20041 ttgattacca ttgaaaaaac tttagattat atagaaaaac atcttttaga tgagatgtta
    20101 gatttaaatg taatttctaa agagataggc tattcaaaat accatttaca tagaatgttt
    20161 acatcagttg tcggatttag tgtacataat tatatacaaa gacgtagact tactgaagca
    20221 gcgagaatgc taatttttac agaaaaacca attattgaga ttgctttaat ctcggggtat
    20281 gacacacaac gctctttttc aagagggttt aaaaaaatgt ttaaacgtag tcctaatttt
    20341 tttagaagac atcaagattt tttaccacta caattaaaat ttgatattca taatagaaaa
    20401 aaattacgtg gagatatggt tttagatgtt aaaaaagtta attgtgcaga tataaatatt
    20461 gttggctatt ctggtaaagt aagaaaagga tttcatatta ttggaaaatg ttggagggat
    20521 ttgcataaaa ataaagagat gatagaaaat aaggtagatt taggtttttt aattggagtt
    20581 agtgattata gcaattttaa agagattgag aatactccta catttacata cattgcaggt
    20641 gctcaagtag ctacttttgg caaattacct aatggaatgg aaaaattcgt attaccgaaa
    20701 agtaattata ttgtttttac ttttattggg aaaaatgagg atagtatgca aaatgttgta
    20761 gaatatatct atcaagaatg gttccctaat tcaagttgcc agtttaatga aaataattta
    20821 tatgactttg taaaatatgg agaaaaaact gatgagaatg gtttgagtga aattcagttt
    20881 tgggttccaa tcatttaaaa gaaggtatta tgtataaagt agatggattt atataggcaa
    20941 agttttacag cagtatgtat ttataaataa tttatagttt gtaggaaaga aataatttta
    21001 ctataagatt atgataaaat acacaatact atgacaaaat agtgttaaat aatagattta
    21061 attttgcata ggaaaagttc tataatggtg tgtattcata aataatttat aatctgtagg
    21121 aaagaaatag ttttactata agattatgat aaaatacaca atactatgat aaaatagtac
    21181 taaataatag atttaatttt gcaaaggata aggtgtttta ataaaaatga atgtagaaaa
    21241 cgaattactt aaaaacctag atagattgca tacaacagag ttaggcgttg taagaattaa
    21301 gaaaaatctt tctttggaga caaatgatgt agtaaactgg tgtaaaacta aaatagaatc
    21361 tccaaatgcc attattaata gaaagggaaa aaactggtat ataagtgtat atgattgtat
    21421 tataacagta aacgctcaca gttatacaat tattacagct cataaagaaa agaaatgaat
    21481 tgcaaaatac aaaggtcaaa agtattttcc actgtttgta gtacctatga agaagtatat
    21541 aaaataatat tacttttgaa taataattta aattttggag gttgaaaaaa tgaatgatac
    21601 tgtaaaagaa aaattggcag agtcactaac ttctgatact actgatattt taccttattt
    21661 gccttattta ttacaagatt tttgggaatt aggaagttca ccagaacaaa tgttacaatt
    21721 atttagaaag catatacctt ttaatgagga tacaaaagtt ttggatttag cttgtggaaa
    21781 aggtgctgta tctgtgaagc ttgcaaaaga gttgaatata catatcaaag gtattgattt
    21841 gatacctgaa tttattgatt atgcgagaag aaaggctatt gaatataagg ttgatgcttt
    21901 gtgtgatttt gaaatgaatg atgctaatag ttctgtaaaa attgagcacg attatgattg
    21961 tgtgattttt ggagctgtag gggatatttt aggtaattat aaagaaacta taagtaagct
    22021 attacctaca ataaaaagta aggggttcat tttaattgat gatgcatatg tagtagataa
    22081 atctacaaat gaacagctta attttgagag ggtgtatccc acttacaatg agtggtgtat
    22141 attgttcaaa gaattaggtc tgaaactaat tgaatgtata ccatgtttag aacttgaaaa
    22201 tgatgttgaa gaggaaatga actggattat aactcgtgca aatgagctaa ttaaaaaata
    22261 tccttctcaa aaagatatgt ttgaacaata tgttattagc caaaaaaatg aatatactga
    22321 tttacagcag gaccttgttg gagcaacttg gattttacaa aaagaataag ataaatatta
    22381 gactagataa tcaatgttgt agtgaattat cccatgtcta gtgaatataa ataacataaa
    22441 aaaccgtcaa gatgaatagt ttattcgtgc ttgacggttt ttagtatttg ttgaagtaaa
    22501 attttatttc tttagtatat cacttttagt caatccattt gatttagcct gagtattcca
    22561 ttgatgattc cccataagtt tatataggaa tctagggaag ttaggtgaaa taaaaatagt
    22621 acttttgttg gaatcatcta tatgtatatt atcactaagt atattttttg aaagttcttt
    22681 taatgcaatt cctaaatctt ttttaggtcc tttacccaaa ggtacggatt ctagtgaacc
    22741 aaacatctcc ccagctccaa ttccaatacc ttgaacccat gtaaagttga tttttttaca
    22801 ccaatgctct atcatttgaa ttgccaaatg attatgttca ccttcattga atccacagtt
    22861 aactattgca tacactggaa taggtttttt attttgtgtt tttaaaaatt tttcacattt
    22921 ctctaaaaaa tgaagtaaat gagacggaat accatctaca taaagaggaa atgctattat
    22981 taatctatca caattaagta tggcattaag agcgtcagga tacttagatg tgctatctac
    23041 tttaaatgta aaaactttat tatcattttg aataagttgt tttaattcag ataaaaaata
    23101 ctgtgaatta tttttattta cttttggact accatttatc attactatat tcatatggat
    23161 tcacctctta tatcctgtat attttcatag aaacaaacag agtgttcttt tatattgaaa
    23221 tttatagcat ttccatttac taatttcgta gcagtttctt tttcagcttc tgtaatacaa
    23281 tctccataga atatagcttt taaatttatc tgtttatcat atctgctttt atgacgcatc
    23341 atattatctt ttattacaaa gtatggaaga atataattaa tgcttttatc aagtacgttt
    23401 ttgacaaaag ggctaaaccc tccgtaacag catctgctta ttataataat tccatcagat
    23461 tcatttataa gtttacccat gttgctgtaa taatctttta caacacattc agaaggagtt
    23521 ttaatccagc aaccaaaaca accaatacat ttatggattt cttttgtgtt tgaaagtatt
    23581 tttatattgt catcaagttt gggtaataac ttttctaatt ctttgtcagt taaatcatgt
    23641 attaaaagcc tcataaagtc catctccttt tattatgtat gtttacttct aaaaattata
    23701 tcttatagat ttttcagtaa atctttacac caattaataa caaaattata atagtcaact
    23761 ccataaatca ttgttgcata catatatgta tattggtcaa cacaatgatt ttcttctgca
    23821 tcattttttt gtttacttaa tttatttaga agtaattcta cttcagttat taacattttt
    23881 aagtttgttt caattatttc tttgggtaga tacttgtaaa agaatatatt aacaaggtgg
    23941 tcttgctttg ttttagaaaa atttataggt ttctttaacc attcaagaaa tacttcttta
    24001 ccagtattag ttatggaata tagttttttt aatttgctac catctataac ttcgtgatag
    24061 tgtatatatc cttttgtttc taatctttta agtgcaggat agatacttcc aaagctggcg
    24121 tcaaaaaagt acgaggtact ttctgacatt atttgtttta agtcgtatcc acttaattct
    24181 ttttccatta aaaatcctaa aataatgtat tctaacatat tacctcctga tatcaattag
    24241 atatatatcg attcgatata tttattatta cagataataa atcttacgtc aagatgcttt
    24301 ttaaaataag ctaaaaagaa ttaggagtta ttgataaata tgcaaaaaaa ttaatataaa
    24361 aggtaattaa atatcaatga agatttaaaa atagttaaat caaagtaaga gtctaatata
    24421 taaaatttat agtaacttta tggtttaaat ataaacttgt gtgctattga caaagtataa
    24481 aattagcagt aaaataattg catgagcaaa tagattattg cgaacgcaaa aaaataagga
    24541 caataaatat taaaggagag aatatgagag agctattaaa atgggtttcc attataaata
    24601 gatacaatac aaattatatt gacaggaaat tggcggatat tggaatcaat aatagccaat
    24661 atttttatgt attacacata tgtaataatc caggtattac acaggacact atatttgaga
    24721 aaattcttgt gaatcctagt aatataacaa gagctttggc aaatttagaa aaagaaggct
    24781 ttataacaag agaaccaggt gtaaaggata aaagaacatg gcatttatat cctacagaaa
    24841 aatctttaga atgttatgat gaaatactaa aaataacaaa tgggtatgtt gaggagttgt
    24901 tgagttcatt tgagaaagaa gagcaagagt tgtttatgtc aatgttaaag aaagttgcat
    24961 ttttggctat tgatatgaat gaagaagcaa aattggaggc gaaggaaaat ggaagaaaaa
    25021 tataaggagc cattggaata tgaaaaggtt tcaaagttat taactaagta cgcaattcct
    25081 agtattatag caatgttagt aagtgcttta tataacattg ttgaccaaat atttattggg
    25141 caaggtgttg gtgtattggg taatgctgct acaaatgtca cttttccact aacaacaata
    25201 tgtaccgcaa ttgcattatt gttaggaatt ggaggagcgt ctaagtgttc attggaatta
    25261 ggtgctaaaa attcagaaaa agctacaaaa gcagcaggaa attctatatg cttgatggct
    25321 gtttttggaa taagtttatt tatagtagta tcaatatttt taacaccact attaaaattc
    25381 tttggctcta catcagaaat actaccttat gcacacacat atacaaaaat tacatcaatt
    25441 ggattaccat ttcttataat gtccactgga atgagtaagt tgatacttgc agatgggaga
    25501 ccaaaagctt ctatgttttg tatgttaata ggagcagtta ttaatacaat tttgaatcca
    25561 ttattcattt ttatttttaa tatgggaatt gctgggtctg ctttagcaac tgttattggg
    25621 caacttatat cttttggaat aagtgttcat tatataaaga attttcaaca tattaaatta
    25681 cataagaaaa gttttaaatt agatagtata atttataaac atatatttgc gctaggttca
    25741 agctcatgtt ttaatcaatt agcaatgact gtaacacaga tagttatgaa taatacattg
    25801 gcatattatg gggctaggtc agtttatgga agtgagattc cacttgcttg tgtcggtatc
    25861 attattaaag taaatatgat ttttatatct ataattattg gtatatcaca aggtatgcaa
    25921 ccaattatag ggtataatta tggggctgaa aagtataatc gtgtaaaaga agcatataag
    25981 tttgcagtgg gaagtgcaac tattatatct gttattgcat tcttatgttt ccaattcttc
    26041 ccaagacaaa ttacgtctat atttggtaac ggaaatgaga cttattttat atttgcagaa
    26101 cattatttta gaactttctt gttcttaaca tttataaatg gtgttcaaat agtatcatca
    26161 actttcttta catcaattgg taaatcagtg ttgggacttt ttacttcttt gactcgtcaa
    26221 attttatttt taattccatt gatagtaatt ttaccaatgt ttatgggaat tgatggagta
    26281 atgtttgcag gaccaatagc agatgcagca gcggcaatgg tatgtatata ctttgcagtt
    26341 catgaaatga aatcattgac tataaagcaa aataatttga tgagtaacca taataagatt
    26401 gcagaggtat aagacaatat ttaagaagta tagaaaatta atttaaagaa gtataataaa
    26461 ctaatttagg aagtatagaa aattaatcta aagaagtata ataaactaat ttaagaaata
    26521 tagaaaatta atttaaagaa atacaataca ttaattttta agtaacatta aattaatgta
    26581 agtaaaataa tgttcatatg aatatttaaa ggtgcatttt ctgaagctaa gtatatgttg
    26641 tagagtgtta tgtctctcta tcctgtgaag tttaatagct caagaaaatg cactatttat
    26701 gatgattatt ttgttttatt tccaattttg gaaataacta ttctaattaa atctaaaatt
    26761 ataccataaa taagaaaaga aagtatagat gctatgtacc aataaatcga aattgaccct
    26821 gtaattgttc tacatgggat ttgcatacct gaatccataa aaacaaaaaa actatcaact
    26881 ctggaaataa tagacaaaat aggatttaaa cctattagaa caatactttt tgagtcttga
    26941 ccaatttgat gcatataaat ctcaaataat gcaattaaaa aaaaccaaga tgtaaaagat
    27001 ttaataattt ttttcatcaa aatacctcac ataatataaa ttctgtttgc actatttgct
    27061 tactacaact atttatctcc attcagtcac atcacttaat tgtaatctag gtcttcttga
    27121 tggttcttca tcaggataac ctaaagatat tgctgccact aattgactat ctgtatttaa
    27181 ccattcacat aattcacgat atgcaaagta tacatcacaa atccaaagac tacctagacc
    27241 taattccaca gctgtaagcg acatattctg aattgcagct ccaattgatt gcatatttgc
    27301 catttcatag aatcgttctt caggggatag cttttctaaa ggtgatttac ctaatatatt
    27361 taaaataaaa attgttactg gagcttgttt catgatttca actgtgtaat ttgcaccagc
    27421 gatatgttga cgacttcctg gaagaagccc attatcatta atttcatttt gaataccttt
    27481 gctcatggct ttaagcatag attctttttc cttttcagtg atgacaacaa aacgccatgg
    27541 ttgcctgttt ttagatgaag gtgcatttat tccagcttca attattttct ctatagtttc
    27601 atgtgaaatg ctttgatttt tatattttct gatacttcgt ctttttgata tagaatcact
    27661 tatcatttta agtaacctcc gtttattttt tggaaaaatc tatttaattt ttattttcta
    27721 ttttaattat tttagcatta atcagaaaaa aagtcattga ttttagtata caattattaa
    27781 tgattatatt aagaattgta tcaaaaagta tgtgattata ctaagggatt atattaaaca
    27841 ttatatttaa aattgtatga aaggttgtat ttaatattat attgagaga
//
LOCUS       DAMJXI010000047        27467 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.049, whole genome shotgun sequence.
ACCESSION   DAMJXI010000047 DAMJXI010000000
VERSION     DAMJXI010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27467
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.049"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            262..2280
                     /locus_tag="PC465_002568"
     CDS             262..2280
                     /locus_tag="PC465_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2649854.1"
                     /translation="MRRNTKLLTTGILSMAIVTPTMAFATESNAMENNADLNINLEKK
                     SIVLGSTSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTESYEGTINYNKDPE
                     YLNVWELQGITINSKNNPKTLNKQELEKMGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSAPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPRDVIIIGDENAISKTTANQIKSTVNASQTRLKGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKNSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNDITKDNVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVY
                     KIGGGLTSKVMNSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSDTGTTGKPLGGIK
                     EKDYTLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLRPDLFTSIHYNAS
                     DTTGNGVEVFYKLKDKDGGTTKTVATNILNRILEKFNLKNRGAKTRTLSTDPTKDYLY
                     VLRNNDMPAVLVECAFLDNEKDMSLLNTSNKVKEMGTQIGKGIEDSLK"
     gene            2785..4797
                     /locus_tag="PC465_002569"
     CDS             2785..4797
                     /locus_tag="PC465_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2649855.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSKSKVSVKFKEKPDADSITLKYKCYDMPLNTTLNYNQSTGAYEGTINYNQDPE
                     YLNVWELQGITINSKNNHKTLNRQDLEKLGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSSPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPKDIIIIGDENAISKTTANQIKSTVNASQTRLNGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKDSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNGITKDSVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVY
                     KIGGGLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSAPGNSSGGMIEKD
                     YNLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLKPDLFTSIHYNGSTNK
                     QGHGVEVFYKLKDKNGGTTKTVATNILNRILEKFKLTNRGIKTRVLPSDSTKDYLYVL
                     RSNDMPAVLVECAFLDNENDMSLINSSAKVKEMGTQIGKGIEDSLK"
     gene            5039..6952
                     /locus_tag="PC465_002570"
     CDS             5039..6952
                     /locus_tag="PC465_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649856.1"
                     /translation="MEYLFEKSSLKEYGNEALDKYRELLDKTGNNSRCILLLVPNNNT
                     KIRYERALRLNYSEELKITTYISFVKKELVKYWPLIIEKCDEISTKVVSPTFISNSLS
                     EYLIVQKVKEKRIQEGYFGDITGTNKSIANSIMTNINKSAFNLIDFDFIGEKIYSSKK
                     NKDSIYRFSYTQMDEIISYYINSLLSNSILDNALSIYLYNQYLLNDDFYLKNLFTEVR
                     YIIVDSLESSSNAEVDFITEALDNTLQSYIYFDYSRDYSVFNNVDIDYINEKIISKIK
                     PKEENIKKKEIRIEDLYLLPANIELNQSSQLYNEMLDLISEKVISLIEEDVSPRDIAI
                     ISPINNSILEHQIRDSLIEKNIDVFSTKKDKKAVDYPYGNALVVATCIFYGYLDFIKD
                     DEYLSFLETLLEINRIKAFKIFNETRHLSIDNIDEHSQYRDILQYIEEKKKSDIKIHE
                     FLTQFYIDKMLNLKEGKKNVGLCKKIIAESESFSESLSLLGMKKEKIFIEALKSTIND
                     YYSVVDIEELKSKDKIVITTPYSYISSNIDRSIQIWVDIGSNAWNMKIEKDISNLIVL
                     RKSFEEKKIYTNEMEEYYKKYYLYNTVYNLLLNAKKIYAFKSEYAINGYIQESILYSI
                     LLKISHKGDKNYD"
     gene            6945..9164
                     /locus_tag="PC465_002571"
     CDS             6945..9164
                     /locus_tag="PC465_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDF2649857.1"
                     /translation="MININYREDQIPIINYDNGTMAVPAVPGAGKTFIITNLVAKLLL
                     EQKHKGGKILILTYMNSAVNNFKGRIRKILEENKIDDTNSYEVMTIHSLAVKIIKEKP
                     EVVMLSEDFNIADDLQKSIILNECISRFRFEGGERAFRWFLKEQKDERWKEITLEAWE
                     RGFFEFAGNAISELKYKGISPDKLEEILSRGHKGMLKIILPIYKLYDRKLKQNGLLDY
                     DDILILAEKTLSLDEGLRKKFQTRYKYIFEDECQDSNEIQGNIIKIISSENKNLVRVG
                     DINQSITGTFSSSDPKFFKEFINSADFCYRMDMSNRSSKDILDLANTLVKYVTKEFRQ
                     KECRHALEDMQIKTVPNGMGYKENPNPEHYNINVKWYESWKIEIEQTARYVKGIKNKY
                     PDKSIGILVPFNEQVTQVAKELRENNLTFEELGPNSLNKRKVINNIAYIIDFMLHCDD
                     VEKLIVVLNKVFIDTDNEEEIKYFLEELKNYSTEEIIYNFEFSKLDNDLIEFKEESDI
                     YLSFKRGIDIIKQILEYPIIRLDLLVLFIGKKLNLEKEDKAVLDYISFYIKYLVSENI
                     NMDLEDVYNLLFDVKNRVFNHIIDVVYEINGYEPEPGSITLCNYHKSKGMEWDCVFLL
                     GLVEYNFPDNINQKFQSDKWYLKEKYKNPMAIIKSEVEAILKGSISTDYAHKTKIDSI
                     NEKIRLLYVGITRAKEMLVLSGSAYRDESDIGNKRKEQKPCIYLSRLNQHIIEKRSN"
     gene            9273..10103
                     /locus_tag="PC465_002572"
     CDS             9273..10103
                     /locus_tag="PC465_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HDF2649858.1"
                     /translation="MNDKLKYFSYSQNSINTYKSCPLKFKYKYIDRINWKNDDVGSRE
                     YYETLKTGRDFHLICERYFSNIPLGIYFNEDDKNSKKFLKWMENIKKVVPIEKGKTYL
                     PEYEVRMTLNGDIIQAKYDLVVIGNNNIEIWDWKTESKKIDYKHVENRIQTIVYMFLA
                     KEVIPKVLKMDINVKDINMRYYQPEFDDLPITILYDEEKHEANRNKIQNYISMIKNTN
                     YEEHTYEDNLYNDIEKVYNKEERMCYRNKKHCKYCEFNKLCNGKEIDYSILEAEIYGT
                     "
     gene            10093..13560
                     /gene="addB"
                     /locus_tag="PC465_002573"
     CDS             10093..13560
                     /gene="addB"
                     /locus_tag="PC465_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HDF2649859.1"
                     /translation="MGLRFVLGRSGSGKSTYILDEIKKEAQKNETTSIILLVPEQYTF
                     EAENRVSKLFLGKEKDKYLRVRVLSFKTLSNIVFSQVGGLTDVNINSSGKAMMVYRAI
                     EDVSEELNVFSKSKSQSGFVSSITDMISEMKQYNISPEMLENISGELDNETLSLKLKD
                     ISKIYNSFEGKLHENYVDAQDMLTSLASKIELSSYLDGACVYIDEFTGFTPNQYNVIK
                     SILNKSKSVNISLTVDDINYIGYSKSDMFSRTKFTYSKLTQLCNEEGIKILPQVNLNT
                     GVIKRFEKVKELQHLERFYNAYPYKIYSNPTENIKIKEFNNLYSEVEEIAREIVHLVR
                     DKNVRYRDITIATRDLNRYDFLVHSIFNEYNIPNFIDKKREAKSNPIVILIISTLEMK
                     NRRYGYETMFRYLKSGLIGIDNDDINLLENYVLANGIKGKKWFDEKWDYRITQSLSGQ
                     ESEFELELKEKINEIKNRVLEPIVILQEKLRGKNRVKEICRYIYEFLLDINMPETIES
                     LIVNFKDKGELDVANQYSQVWDIVVDILDQMVELMGDEIISLEKFIKLITLGFDEYEL
                     GLVPPSIDQVLVSSVDRMKNPDTKYLYLVGTTDGVFPLITKDSGILSDNDRESLGNKG
                     IEVDIDSKTRSFEEQFLVYKALTSTSKNLTITYPISDHEGKTLRPSIIISRLKKIFPN
                     IENKSYLVEENKSTDKDILKKITVKSPTFNELINIIKNYDSDGYNTEEINSIWLDIYR
                     YYLKDEVYSSITKKVIKGLSYTNQVHKIEEKKIRSLYKSNSLSISRLEKYAECPFAYF
                     IQYGLKAKKRKEYSFTPPDLGTFIHNILDRFSKELLQDNLTWRDIDEKYIELKIGIIV
                     DEIILKIPGYILNSSERYKYLAYRLKNMLTTAITIISQQIKQGSFEPIDYEVKFGNNG
                     KYPPIKMVLENGQEVSLIGQIDRVDEFEEGENKYIRIIDYKSGNKSISLTEIYYGLQL
                     QLLVYLDAILESAKDEDININPAAILYCRINNPIAKFNEDKDDEEIQEAILKELRMKG
                     LVVKDSHIVKEMDKSLIDGERKNSLVIPVGLTKDGNVGKSTSAISYEDFKLLRKYVRH
                     AIKDLCEEMLSGEIRIAPYKHKDGTSCDFCDYSAICQFDSTIKDNKYKNLNNKSNEEI
                     IKMMKGDVN"
     gene            13560..17387
                     /gene="addA"
                     /locus_tag="PC465_002574"
     CDS             13560..17387
                     /gene="addA"
                     /locus_tag="PC465_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HDF2649860.1"
                     /translation="MSSPKWTKEQLEVIESRECNLLVAAAAGSGKTAVLVERIIQMIT
                     SRENPIDIDKLLVVTFTNAAASEMRERIGDAIGKALDENPENKHLQNQLVLLNKSSIT
                     TIHSFCLDVIKSNFHRINLDPNFRIGDQTECAILKQEAIEEVFEDLYEERDEGFLNLV
                     ESYAERGGDKEVQDIILGIYSFAMASPEPKKWLIDSAERFNIDENFDFSQSIWARAIL
                     DTVKIEINGLCLNMERALKEVESIEELETFAEKLSVEYKKIADISQACNKSWDEAYKK
                     MASMSFENYVKGVKRISKDAPSYIKESKEKAKTIRDKTKKSLESIVSATFNKDNDSIR
                     EEIKYLYNIVKPISSVVLRFEEEYSNKKREKGIIDFNDIEHFALNILTDVDEKGNIVP
                     SDIAVGYRNKFYEIFIDEYQDSNLVQEVLLKAVANTETPNRFMVGDVKQSIYRFRQAK
                     PELFLQKYNNYNDKKGSSHRKIMLYKNFRSREEVVDAVNYIFENIMNENIGEIEYTEK
                     ERLNLGANFNVDTDEKSIIGGATEIHLIQKDNKLDDDIINDKDDRINNKEDEIEEEEK
                     LDNIQLEARMVGNIIKDLMKVNEDGKIQKVYDKGIDGYRPVEFRDIVILLRATSAWAP
                     VFADELMNMDIPTYADVGVGYFDTIEIKTILSLLQIIDNPMQDIPLISVLKSPIFGFT
                     PEDLIDIRVQSKDKIFYEVLKSTAEYDGFTDSQNENESEFIPSEECINKSKDFLIKLK
                     EFKEKSMYMSTDEFIWYLYTRTGYYAYVGALPGGSQRQANLKVLFERAKQFEETSLKG
                     IFNFVNFIEKLKKSSSDMGSAKTLGENANVVRIMSIHKSKGLEFPVVICSAMGKNFNT
                     QDFKKSILYHHNLGYGPQFVDYERRISFPSIAKEALKSKINIENLSEEMRVLYVAFTR
                     AKEKLIITGSTRNIQDSIKRWSNGIESLDTISQYEILKGKNFLDWIMPCVLRHRDLSN
                     LLEEVGLDAVFNVEHNSKWYGKLWNKNDILVEKKSDEEKESIEEILEKIDVDNPDSDY
                     YSEIEEKLNYIYPYEFSTRKPATISVTEIKKIQNNYEEELINTIFEQKVILKKPLFIQ
                     NEEEREKISGTERGTIVHLVMEVLDLKNVSSVNDIKSQIRGFVSKGIITEKQASIVNP
                     YKIYKFFASNIGKRMLNAEIINREKSIYAQVNMKDIYIYEKLINNDDKKLYDNESVML
                     RGIVDAYFEEDNQIVLVDYKTDFVNEENINQIIEKYKKQLDLYADIIETLTGKSVKEK
                     CIYLFGVDEAVCY"
     gene            17433..18644
                     /locus_tag="PC465_002575"
     CDS             17433..18644
                     /locus_tag="PC465_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HDF2649861.1"
                     /translation="MRFIHTSDWHLGKSLEGHSRIEEQAKFCEEFIKIVESNEIDMVI
                     IAGDVYDTSNPPAQAEKLFYQTVSRLANNGQRCVLIISGNHDNPERLSAITPLAHEQG
                     ILIYGYPLSATIEAKYKGFEITYATQGCTKLNINGENIVVATLPYPSEKRLNEVFSSE
                     DEFEKQKNYSEKVGDIFRSLEENFRSDTINIAVSHIFVIGGESTESERPIQLGGSFLV
                     ERKDLPEKAQYTALGHLHKQQKASERLNAYYSGSPLQYSKDERAYTKGAYIVDIKAGE
                     KPIIEDVYFNNYKPIEVFKCNGIEEALDICEQNQDREIWSYFEINTDEIISQNEIKKM
                     KELLKDIIEIKPIITSCYEQESVDIKEKSMAELFREFYSFSKGVEPKGELMDLFLDII
                     SEEGESADETN"
     gene            18631..22158
                     /locus_tag="PC465_002576"
     CDS             18631..22158
                     /locus_tag="PC465_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2649862.1"
                     /translation="MRPIRLELTGLNSYIDKQVIDFEKLIERGLFGIFGTTGSGKSTI
                     LDAITIAMYGNISRNTKEYINSVCDKAIISYEFEIGSKNTRRRYIVDRTIARSKTGTK
                     TSNARLIEVLNDNTQNVLADKVVEVNEKVAQVVGLTANDFTRSVVLPQDKFNEFLRLS
                     RADRRDMLERIFNLEKYGRSLGEKVKKRKNIQLQNLKDLKSKLSQYDGITEEVYNNIN
                     QELIELKNLEKDKNNALDLAQKSYEESKTVYEEQLKLEKNELRKNELDLKNSEIKEKI
                     ALVENDSNAKKVDPYISSVQNLEKKIDEDSFAVSNLEKKLAILNQELEVTKNRYEKIN
                     KIKNEEVPKLSEEKIRLQQAIKLEEELVLLDRELKELKESGINLNKTKVELEKVKQVS
                     ESRKDAVTKSIKEVEGKIDKVNISAELKQKIFLAYEYEKDYNNVLEEKNQKLNKLEEI
                     LKETENINLKVRYIDKDKNDVNRNLENLSLHLDVLLKKCPGKSADLLLKSEYVTELRN
                     KANNTKENEIKKSSIQDELKIILESKFNTEREVNLLNEKLENNRKNRDDLEKELEELK
                     YLNLASELRRELKENMPCPVCGSKHHENHNITKYDENISFVKEKLEKLEKEKISIRNN
                     IEELNAKVSGYLSIEKMKTKELEDVKGKLGGIPSSQLLKKLDEEQRKLALLKSNIQEW
                     EKEKESTENKVTLAKEEKNKIEKEELKIRESLNNYKKLTRDLNIEIEGLENKCKKLKQ
                     EYLGLKTITKVSNLLSKVKEIRENEKELELLSTGHSNLLKNRDSLDIKIRENESKLHE
                     IEIELIKARELYVEKKLSRDNKYKEVISITKGDLAKNLLHNVEENICKILEQEESSKK
                     KLEEQRLEYEKNIAEKHNIDGRLKTAKEQYKDQKSTLNKLLAENKFESIYAVKRALLD
                     TDAVKKLIEEILEHEEEQKLLSFKIKSSKEKLNGRSIKKEYFEQLKDEIYNLKVEIGN
                     ISKDIGANQNQLITLKDSLDKINDFNKQLKVVEHNVDLLEELDKCVQGNKFVEYVSTN
                     QLKYIALEASKRLDGITKGRYALEIDSTLNFVMRDNFNGGERRSIDTLSGGETFLTSL
                     SLALALSSQIQLKGSAPLEFFFLDEGFGSLDSELLEIVIESLERLHSNNLSVGIISHV
                     EELKNRVPVKLLVSSSEAGIGSKVKIEYS"
     gene            22289..23542
                     /locus_tag="PC465_002577"
     CDS             22289..23542
                     /locus_tag="PC465_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDF2649863.1"
                     /translation="MLESPNNLIQIIFLIVLLIGSAFFSASETALMSLSKIRIRYMQD
                     EGVKGAKLVSSLIENPNKLLSSILVGNNVVNIAATSISTSLFIGLMGEKGVALATAVM
                     TVLVLIFGEITPKTIAANNSEKVSLLVSKPIKAIIFILRPIVWIFNIITNIIFKLFGI
                     TNKGAKSFITEEELKTMVNVSHEEGVLEMEEREIINNVFEFGDMQAKNAMVQRIDMVA
                     IDMEDSYDEIIQVFKTEKLSRMPVYEETIDDIVGILNIKDIIFLSDEEIESFDIKNYM
                     REPFFTYEFKKITQLLEEMKLEKSQMAIVVDEYGGTSGLLTIEDLVEVIVGDIEDEYD
                     EEEDEIQVIKEDEYIVDGSTKIGDVNELIGVNLESEEFDSIGGFIIGHLSRLPEENEV
                     IEVDNIRFCIESIEKNRIKKIRIYT"
     gene            23691..24743
                     /gene="ytvI"
                     /locus_tag="PC465_002578"
     CDS             23691..24743
                     /gene="ytvI"
                     /locus_tag="PC465_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HDF2649864.1"
                     /translation="MSILENNFLYKLKNNTIFFCIYTLLFIFIYKAFPYIAPFFLGAI
                     IALMINPISQKLENKFHINKGISTLVLSFLAVAIVSTVTTIIVINSMKELMGFLNNIS
                     ANPEDISNTIMYFLNKINDFMKSFQEIANFDVEQLVNKFSGEVMQITKNLLTSILGLA
                     TSIPYIIIFIITLFIATYFIAKDLDKIENSFYNMFTVDVRKKVKNVKKEAGLSLVGYI
                     RAYTILMAITFFAIWGSFALFGLKYGLIVGFVGALMDLIPFLGIITIYLPVIVYYFLI
                     KNYFIAISMTVIFFVLSLIREILEPKLVSVNVGLNPLATLAAIFIGIQVKGIIGVIFC
                     LGLVCMHDILKKVDIF"
     gene            24834..26060
                     /gene="pepT"
                     /locus_tag="PC465_002579"
     CDS             24834..26060
                     /gene="pepT"
                     /locus_tag="PC465_002579"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HDF2649865.1"
                     /translation="MKQKVVERFLKYVSFDTTSNSQCENCPSSEGQRVLAKYIVEELK
                     TMGVDDVSLDENSYIMATLKGNTDGVDTIGFISHLDTIEDVSGKDIKPRIIENYDGKD
                     IVLNEALNVITYVKDSPELEEFKGDDLIVTDGTTLLGSDDKAGIAEIVTAIEYLINHP
                     EIKHGDIKIGFTPDEEIGRGADLFDVEKFGAKYAYTLDGGIVGELECENFNAANATIT
                     IHGRNVHPGSAKNKMVNAIHIAAEISEMFPADERPETTEGYEGFWHLNSIGGNVENVS
                     MAYIIRDHCREKFENRKSIMIENIEKINKKYDNRVELDLKDSYYNMKEKIEPVMFIVD
                     IAKEAMEELGIKPRLVPVRGGTDGARLSFNGLPCPNIFTGGLNFHGKNECIPVSSMEK
                     ATKLIVRIAEKYAERV"
     gene            26267..27319
                     /locus_tag="PC465_002580"
     CDS             26267..27319
                     /locus_tag="PC465_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp18"
                     /protein_id="HDF2649866.1"
                     /translation="MKIKSKKIIAFALSLGIMLPSCVYADTISKNQNAQVDMNNYLQG
                     RKSPKEEKLIGEDRFDTAIKISHSGWNNGSERVFLVNSNSLPDALASTPLASKLDAPI
                     LLTNKNSIPYNVTEEIKRLNPAEVILIGSEGAISSSVKESLEDMEVLVSRIGGADREE
                     TSLLLTRQLDDTGDLGVSKVAVVNGYNGLADATSISSPAASDNTAIIYTGKDSIRSEA
                     KNFITQNSTKTYIVGGEYSISKKLEGQLVNSERLAGTDRKDTNAKVLEKFYGKSSKVN
                     NMYFAKDGSGREADLVDGLAAGVLASKTKSPVVLASGSLSSAQKSFIKKVKADKFVQV
                     GGGKNSKPYAEALALQ"
BASE COUNT        11685 a         2672 c         4846 g         8264 t
ORIGIN      
        1 ttgtattaaa tttaataaac ctacaattat tatatgtttt tatttgtctt ttatagattt
       61 ttttggcaat aaatgatata gtgaagataa ttaaatatat tcaatatatt taattttttt
      121 attttttgtt tttataattt ttttagaagt ttatttttta tgtacttatt tataattttg
      181 ggtaaaaaca ctttgatata ttttcaaaag ataaaagatt aaaaaacaag gtagaaattt
      241 atgttaagta aggagattaa tatgagaaga aatacaaaat tattaacaac aggaattctt
      301 tcaatggcaa tcgtcacacc tacaatggca tttgctactg aatctaatgc tatggaaaat
      361 aacgctgatt taaatataaa cttagagaaa aaaagtatcg ttttaggtag tacctcaaaa
      421 gtcagtgtta agtttaaaga aaaaccagat gcagatagca ttacattaaa gtataaatgc
      481 tatgatatgc cattggatac aactttaaat tataatcaat caactgagtc atatgaagga
      541 actatcaatt ataataaaga cccagaatat ctaaatgttt gggaactaca agggataaca
      601 ataaacagca aaaataatcc taaaacttta aacaaacaag aactagaaaa gatgggatta
      661 aatttaaaag actataatgt aacgcaggaa tgtataattg aagatataac ttctagaaaa
      721 gatgtaaata aatatttaag aaaaacttct gcacctatta cagaacttac aggaagtgat
      781 agatacgaaa cagcagttaa aataagtaaa gaaggctgga aaaatggttc agataaggta
      841 gttataataa atggagatgt aagtatagat ggcattatat caactccact agcaactaca
      901 tataatgcgc caatactttt ggttgaaaaa aacaatgtac ctaatagtgt aaaatcagaa
      961 ttaaagcgtt taaatcctag agatgtaatt ataattggag atgagaatgc tatttctaaa
     1021 actactgcta atcaaattaa atcgactgta aatgctagtc aaacacgtct aaagggctct
     1081 aatagatatg agacatcttt attgatagca aaggaaatag ataaaaatca tgatgtggaa
     1141 aaagtataca taacaaatgc taatggcgga gaagtggatg cacttactat agcagcaaaa
     1201 gcaggtcaag acaagcaacc aattatatta actgataaaa atagtattac agacaacaca
     1261 tataaatggt taaagagtga ggatttacaa aatgcttatt ttataggtgg tcctcaaatg
     1321 atatcaacaa atgttataaa taaggtaaat gatataacta aagataatgt tactaataat
     1381 agagtatatg gagcagatag acacgaaaca aatgcaaacg taataaaaaa attctataca
     1441 gatgatgagt tagaggctgt tttagtagct aaatcagatg tacttgttga tgctttagca
     1501 gcaggtccat tggctgccaa cttaaaatct ccaatactta taacaccaaa gacgtatgta
     1561 tctgcatacc ataaagataa tttagaagct aaatcagcta ataaagtata taaaatagga
     1621 ggaggattga cttctaaggt aatgaactct atagcatcat cattatctaa acacaataca
     1681 actccaacag aaccaggaaa tagtgggggt aagacagtta tgattgaccc aggacatggt
     1741 ggttcggaca ctggaacaac aggtaaacca ttagggggta ttaaagaaaa agactataca
     1801 ttaaatactt cacttgcgac aactgaatat ttacgttcaa agggattcaa tgtaataatg
     1861 acaagagaca cagataagac tttatctctt ggaaatagaa ctgctttatc taactctttg
     1921 agaccagatt tatttacgag tatacactat aatgcatctg atacaactgg gaatggtgta
     1981 gaagtatttt ataagcttaa agataaagat ggagggacta ctaaaactgt agctacaaat
     2041 atattaaata gaatcttaga gaaatttaat ctaaaaaata gaggtgcaaa aacaagaaca
     2101 ctatcaactg accctacaaa agattattta tatgttttaa gaaataatga tatgccagct
     2161 gtacttgtag aatgtgcatt tttggataat gagaaagata tgagtttact taatacatca
     2221 aataaagtaa aagaaatggg tacacaaata ggtaaaggca tagaagattc attaaaatag
     2281 tctacaatga gagcatagaa aaatttaaaa taaattaatc tgcaatttta aatttaaact
     2341 aaagctataa gataagaatg taattataat agtaataaag actgtatata cattgtgcat
     2401 ataagtgcga aatgaggtat atacagtctt tttatgatta attgtaaaag gatttatatt
     2461 atatgaagaa tttacatatc ttaaggctac agttaattgt caagagttgg agtattcatt
     2521 tgtaatacac aataaaagct taattactat attttattgt gtgtttgtgt gttttttgtg
     2581 gatttttatg tcaataaatg atatagtata gataattaaa tgtattaaat atatttaatt
     2641 tttttatttt ttgagtttta taagtttatt tttatatatt acttatatat tatttatatt
     2701 ttgggttaga tacactttga catattttca aaagttaaaa gattaaaaat aaagtagaaa
     2761 tttatgttaa gtaaggagat taatatgaga agaaatacaa aattattaac aacagggatt
     2821 ctttcaatgg caatcgtcgc acctacaatg gcatttgcta ctgaatctaa tgctatggaa
     2881 aataacgctg atttaaatat aaacttagag aaaaaaagta tcgttttagg tagcaaatca
     2941 aaagttagtg tcaaatttaa agaaaaacca gatgcagata gcattacatt aaagtataaa
     3001 tgctatgaca tgccattgaa tacaactcta aattacaatc aatcaactgg ggcatatgaa
     3061 ggaactatca attataacca agacccagaa tatctaaatg tttgggaact acaagggata
     3121 acaataaaca gcaaaaataa tcataaaact ttaaacagac aagacctaga aaagctggga
     3181 ttaaatttaa aagactataa tgtaacacag gaatgtataa ttgaagatat aacttctaga
     3241 aaagatgtaa ataaatattt gagaaaaact tcttcaccta ttacagaact tacaggaagt
     3301 gatagatatg aaacagcagt taaaataagt aaagagggct ggaaaaatgg ttcagataag
     3361 gtagttataa taaatgggga tgtaagtata gatggcatta tatcaactcc actggcaacc
     3421 acatataatg caccaatact tttggttgaa aaaaacaatg tacctaatag tgtaaaatca
     3481 gaattaaagc gcctaaaccc taaagatata attataattg gagatgagaa tgctatttct
     3541 aaaactactg ctaatcaaat taaatcaact gtaaatgcta gtcaaacacg tttaaatggt
     3601 tctaatagat atgagacatc tttattgata gcaaaggaaa tagataaaaa tcatgatgtg
     3661 gaaaaagtat acataacaaa tgctaatggc ggagaagtgg atgcacttac tatagcagca
     3721 aaagcaggtc aagacaagca accaattata ttaactgata aagatagtat tacagacaat
     3781 acatataaat ggttaaagag tgaggattta caaaatgctt attttatagg tggtcctcaa
     3841 atgatatcaa caaatgttat aaataaggta aatggaataa ctaaagatag tgttactaat
     3901 aatagagtat acggagcaga tagacacgaa acaaatgcaa acgtaataaa aaaattctat
     3961 acagatgatg agttagaggc tgttttagta gctaaatcag atgtacttgt tgatgcttta
     4021 gcagcaggtc cattggctgc gaacttaaaa tctccaatac ttataacacc aaagacgtat
     4081 gtatctgcat accataaaga taatttagaa gctaaatcag ctaataaggt atacaaaata
     4141 ggaggaggat tgacttctaa ggtaatgagc tctatagcat catcattatc taaacacaat
     4201 acgactccaa cagaaccagg aaatagtggg ggcaagacag ttatgattga cccagggcat
     4261 ggtggttcag cacctggaaa ttcatctgga ggaatgattg aaaaagatta caatttaaat
     4321 acttcacttg caacaactga atatttacgt tcaaagggat tcaatgtaat aatgacaaga
     4381 gacacagata agactttatc tcttggaaat agaactgctc tatctaattc attgaaacca
     4441 gatttattta caagtataca ttataatggc tcaactaata aacaaggtca tggtgtagaa
     4501 gtattttata agcttaaaga taaaaatgga gggactacta aaactgtagc taccaatata
     4561 ttaaatagaa ttttagagaa atttaaactt acaaatagag gtataaaaac aagagtactt
     4621 cctagtgatt ctacaaaaga ttatttatac gttttaagaa gtaatgatat gccagctgta
     4681 cttgtagaat gtgcattttt ggataatgaa aatgatatga gtttaataaa ctcatctgca
     4741 aaagtaaaag aaatgggtac acaaataggt aaaggaatag aagattcatt aaaataaatg
     4801 gaaataaaaa tatttaaaaa cttaatgtaa atttatagtt gtaaatttat actaaagtca
     4861 aaaaatgaaa tataagtgta tcaatagtaa gactgtatgt acatttgcac atgtgaatgc
     4921 aagtatatat acagtctttt tttgtagtta aatgcaataa tttgattgtg ttttgtaaaa
     4981 tacacaatat gatataatta gataatatac acttaattta attgaggaag gtgattatat
     5041 ggaatattta tttgaaaaaa gtagtttaaa agaatatgga aatgaagctt tagataaata
     5101 tagagaatta ttagataaaa ctggtaataa ttcaaggtgt attcttttgt tagtaccaaa
     5161 caataacaca aagatacgat atgaaagggc tctaagatta aattatagtg aagaactgaa
     5221 aataacaaca tatataagtt ttgtgaagaa agaattagtt aaatactggc cactaataat
     5281 agaaaaatgt gatgaaataa gtacaaaggt tgtatctcca acatttatat caaatagttt
     5341 aagtgaatat ttaatagtgc aaaaagttaa ggaaaaaagg atacaagaag gatattttgg
     5401 agatattaca ggaaccaata aatccatagc aaatagtata atgactaaca taaataagtc
     5461 tgcatttaat ttaattgatt ttgattttat tggagaaaaa atatattcat caaagaaaaa
     5521 taaagatagt atatatagat tttcatacac tcaaatggat gaaattatat catattatat
     5581 aaattcctta ctatcaaatt caattttaga taatgcatta agcatatatt tatacaatca
     5641 atacctactt aatgatgatt tttatttaaa aaacttattt acagaagtga gatatataat
     5701 tgtggatagc cttgaaagct caagtaatgc agaagttgat tttataacag aagcattgga
     5761 taatacatta caaagttata tatattttga ttatagtagg gattattctg tatttaataa
     5821 tgtggatata gactatataa atgagaaaat aatatcaaaa attaagccta aagaagaaaa
     5881 tattaaaaag aaggagatta gaatagaaga tttatactta ttacctgcaa atatagaatt
     5941 aaatcaatca agtcaattat ataatgaaat gttagattta ataagtgaaa aagttatatc
     6001 tcttatagaa gaagatgtat ctccaagaga tatagcaatt atatctccta taaacaatag
     6061 tatattggag catcaaatta gagattcttt gatagaaaaa aatatagatg tttttagtac
     6121 taagaaggat aaaaaagctg tggattatcc atatgggaat gcattggtag tggctacatg
     6181 tatattctat ggatatttag attttataaa agatgatgaa tacttaagct ttttagaaac
     6241 tcttttagaa ataaatagga taaaagcatt taagattttt aatgaaacaa gacatttaag
     6301 tattgataat atagatgaac atagtcagta tcgtgatatt ttacagtata ttgaagaaaa
     6361 aaagaagagt gatataaaaa tacatgaatt tttaactcaa ttttacatag ataaaatgtt
     6421 aaatttaaaa gaaggtaaaa agaatgttgg gttatgtaaa aagataatag ctgaaagtga
     6481 gtcttttagt gaaagtttaa gtctacttgg gatgaaaaaa gaaaagatat ttatagaagc
     6541 tttaaaaagt acaataaacg attattactc tgttgtcgat atagaagagt tgaaatccaa
     6601 agacaaaata gtaataacta ctccttattc atatatatca tcaaatatag atagaagtat
     6661 acaaatatgg gtagatatag gaagtaatgc ttggaatatg aaaatagaaa aagatataag
     6721 taatttaatt gtacttagaa aatcttttga agaaaaaaag atttatacaa atgaaatgga
     6781 agaatattat aaaaaatatt atctatacaa tacagtatat aatttgttat taaatgcaaa
     6841 gaaaatctat gcatttaaaa gtgaatatgc gattaatggt tatatccaag agagtatatt
     6901 gtatagtata cttttaaaaa tctcacataa aggagataaa aattatgatt aatataaatt
     6961 atagagaaga ccagatacca ataataaatt acgataatgg tactatggca gtaccagcag
     7021 taccaggtgc tggaaaaaca tttataataa caaatttagt agctaaacta ttacttgaac
     7081 agaaacataa gggtggtaaa atattaattc ttacatatat gaatagtgct gtaaataatt
     7141 ttaaaggtag aataagaaag attcttgaag agaataaaat agatgatact aattcgtatg
     7201 aagtaatgac tatacacagt ttggctgtaa aaataataaa ggaaaagcca gaagttgtaa
     7261 tgttaagtga ggattttaat atagctgatg atttgcaaaa aagtattata ttaaatgaat
     7321 gtataagtag atttagattt gaaggtggag aaagagcttt tagatggttt ttaaaggagc
     7381 aaaaagatga acgctggaaa gaaataactc ttgaagcctg ggaaagaggt ttttttgaat
     7441 ttgcaggaaa tgcaataagt gaacttaagt ataagggaat ttctccagat aaacttgaag
     7501 aaatattgtc aagaggacac aaaggaatgc ttaaaattat tttaccaata tataaattgt
     7561 atgatagaaa attaaagcaa aatggattgc tagattatga tgatatatta attttagcag
     7621 aaaaaacttt aagcttagac gaagggctta gaaagaagtt tcaaactaga tacaaatata
     7681 tatttgaaga tgagtgtcag gactcaaatg aaattcaagg taatataata aaaattatat
     7741 ctagcgaaaa taaaaaccta gttagagttg gagatataaa tcagagtata acaggaacat
     7801 tttcatcatc agaccctaaa ttttttaaag aatttataaa tagtgcagat ttctgttata
     7861 ggatggatat gtcaaatcga agttcaaaag atatacttga tttagcaaac actcttgtca
     7921 agtatgttac aaaggaattt agacagaaag aatgtagaca tgctcttgaa gatatgcaaa
     7981 taaaaactgt gccaaatgga atgggatata aagaaaatcc taatccagaa cattataata
     8041 taaatgtaaa gtggtatgag agttggaaaa ttgaaataga gcaaactgct agatacgtta
     8101 agggtataaa aaataaatat ccagataaaa gtataggtat attggttcca tttaatgaac
     8161 aagtgacaca agttgctaaa gaacttagag agaataatct aacctttgaa gaattaggac
     8221 caaattcttt gaataaaagg aaggttataa acaatatagc atatattatt gattttatgt
     8281 tacattgtga tgatgtagaa aagttaatag ttgtacttaa taaagttttt atagatactg
     8341 ataatgaaga agaaataaag tattttttag aagaattaaa aaactattct accgaagaaa
     8401 ttatttataa ttttgaattt agtaagttag ataatgattt aatagaattt aaagaagaaa
     8461 gtgatatata cttaagtttt aaaagaggaa tagatattat aaaacagata ttagaatatc
     8521 caataataag gttagacctc ttagttttgt ttattgggaa aaaacttaat ttagaaaaag
     8581 aagataaagc tgtactggat tatatatctt tttatataaa gtatctagta tcagaaaata
     8641 taaatatgga tttagaagat gtatataatt tattgtttga tgtaaagaac agggtgttta
     8701 atcatataat agatgtggta tatgagataa atggatatga accagagccc ggtagtataa
     8761 cactatgtaa ctatcataaa tcaaagggga tggaatggga ttgtgtgttt ttactaggtc
     8821 ttgttgaata taatttccct gacaatatta atcaaaagtt tcagagtgat aaatggtatc
     8881 taaaagaaaa atataaaaac cctatggcaa ttattaaatc agaagttgaa gctatattaa
     8941 aaggaagtat ttcaacagat tatgctcata aaacgaagat tgattctata aatgaaaaga
     9001 ttagactttt atatgtaggg attactagag caaaggaaat gttagtactt tcaggaagtg
     9061 cttatagaga tgaaagtgat atagggaata agagaaaaga gcaaaaacca tgtatatatt
     9121 taagcagact taatcaacat attattgaaa aaaggtcaaa ttaatatata ataagttatt
     9181 aaaagattgc ttgaaatata tctaaaaggg gataaaacaa tatgtacagt aagtaactac
     9241 taaaaaataa agttaagaga gaagtgatat gagtgaacga taaattaaaa tatttttctt
     9301 atagtcaaaa ttcaattaac acatataaat catgtccatt gaaatttaaa tataaatata
     9361 ttgatagaat aaattggaaa aatgatgatg ttggtagtag agagtattat gaaactttaa
     9421 aaacaggaag agattttcat ttgatttgtg aaagatattt tagcaatata cctcttggaa
     9481 tctattttaa tgaggatgat aaaaatagta aaaagttttt aaagtggatg gaaaatataa
     9541 aaaaagttgt tcctattgaa aaaggaaaaa cgtatttgcc agaatatgaa gtaaggatga
     9601 cattaaatgg ggatataata caggcaaagt atgatttagt tgtaattgga aataacaata
     9661 tagaaatatg ggattggaaa accgagtcta aaaagattga ctataaacac gtagaaaata
     9721 gaatacaaac tattgtttat atgtttttag caaaagaagt aatacctaaa gttttaaaaa
     9781 tggacataaa tgttaaagat ataaatatga gatattatca acctgaattt gatgacttac
     9841 caattaccat tttatatgat gaagaaaaac atgaagcaaa tagaaataaa attcaaaatt
     9901 atataagtat gataaaaaac actaattatg aagaacatac atacgaagac aatctataca
     9961 atgatataga aaaggtatat aataaagaag aacgtatgtg ctatagaaat aaaaagcatt
    10021 gcaagtattg tgaatttaat aagttatgta atggcaaaga aatagattat agtattttgg
    10081 aggcggaaat ttatgggact taggtttgta ttaggtagaa gtggaagtgg aaaatccacc
    10141 tatatactag atgagattaa aaaagaagct caaaaaaatg aaacgacatc aattatactt
    10201 ttagttccag aacagtacac atttgaggct gaaaatagag taagtaagct attcttagga
    10261 aaagaaaaag ataagtatct aagagttagg gtacttagct ttaagacact aagtaatata
    10321 gttttttctc aagtaggagg attgacagat gtaaatataa attctagtgg aaaagcaatg
    10381 atggtatata gagctattga agatgtaagt gaagaattaa atgtgttttc aaaatcaaaa
    10441 tcgcagtctg gttttgtaag ttcaattaca gatatgatat cagaaatgaa acaatacaat
    10501 ataagccctg aaatgttaga aaatatatct ggagaattgg ataatgaaac tttaagttta
    10561 aaattaaaag atataagtaa aatatataat tcttttgaag ggaaattgca tgaaaattat
    10621 gtagatgctc aagatatgtt aacttcattg gcaagtaaaa ttgaattaag cagttattta
    10681 gatggagctt gtgtttatat agatgaattt acaggtttta caccaaatca gtacaatgtc
    10741 ataaagagta tattaaataa gtctaaaagt gttaatatct ctttgactgt agatgatatc
    10801 aactatattg ggtacagtaa atctgatatg ttttctagaa cgaaatttac ttattcaaaa
    10861 ttgactcaat tgtgcaacga agaaggcata aaaatattgc cacaagtaaa tttaaacaca
    10921 ggtgttataa aaagatttga aaaagttaag gaattacagc acttagaaag attttataat
    10981 gcttatccat ataaaatata ttcaaatcca actgaaaata taaagataaa agagtttaac
    11041 aatttatatt cagaggtgga agagatagcc agagaaattg tacatttagt tagagataag
    11101 aatgtcagat atagagatat aaccattgct acaagagatt taaatagata tgatttttta
    11161 gtacactcta tatttaatga atataatata ccaaacttta tagataagaa gagagaggca
    11221 aaaagtaatc caatagttat tttaattatt tcaactttag aaatgaagaa tagacgatat
    11281 gggtatgaaa ctatgtttag gtatttaaaa agtggactta taggaattga taatgatgat
    11341 ataaatttac tagaaaatta tgtgttggct aatgggatta aaggtaaaaa atggtttgat
    11401 gaaaaatggg attatagaat aactcaaagt ctttcaggtc aagaaagtga atttgaactg
    11461 gaattaaaag agaaaataaa tgaaataaaa aatagagtat tagagcctat agtaatttta
    11521 caagaaaaat taagaggaaa aaatagagta aaagaaatct gtagatatat atatgaattt
    11581 ttattagata taaatatgcc agaaactata gaaagtttaa tagtaaattt taaggataaa
    11641 ggggaacttg atgttgcaaa tcaatactca caagtttggg acatagtagt ggacatatta
    11701 gaccaaatgg tggaacttat gggtgatgaa ataatttctt tagaaaaatt tataaaatta
    11761 ataaccttag gttttgatga atatgaatta ggactggttc ctcctagtat agaccaggta
    11821 cttgtaagta gtgtggatag aatgaaaaat ccagacacga aatatttata cctagttgga
    11881 actactgatg gtgtgtttcc gctgattaca aaggatagtg gaatattgag tgataatgat
    11941 agggaaagtc ttggaaacaa aggaatcgaa gttgatattg atagtaagac taggagtttt
    12001 gaagaacagt ttcttgtata taaagctctt acttcgacat ctaagaattt aaccataaca
    12061 tatccaatat cagaccatga aggtaaaacg cttagaccat caataattat atcaagactt
    12121 aagaagatat ttccaaatat agaaaataaa agttatttag tggaagaaaa taaaagcact
    12181 gataaagata tacttaaaaa aataacggtt aaatccccta catttaatga acttataaac
    12241 ataataaaaa attatgacag tgatggttac aatacagaag agattaatag tatttggtta
    12301 gatatatata ggtactattt aaaagatgaa gtctatagtt ctataacaaa aaaagttata
    12361 aaaggtctta gttatactaa tcaagttcat aagattgaag agaaaaaaat aaggtcattg
    12421 tataaaagta attctcttag catatctagg cttgaaaaat atgctgaatg tccatttgct
    12481 tattttatac aatatggtct aaaagcaaaa aagcgtaaag agtattcatt tacaccacca
    12541 gatttaggaa cttttattca taatatttta gataggtttt caaaagaact tttacaagat
    12601 aatttaactt ggagagatat tgatgaaaaa tatatagaat taaagatagg tataatagtt
    12661 gatgaaataa ttttaaagat accaggatat atattaaata gttctgagag gtataaatac
    12721 cttgcatata gattaaagaa tatgttgaca actgctataa ctataattag tcagcaaata
    12781 aaacaaggtt catttgaacc aatagattat gaagttaaat ttggcaacaa tggaaaatat
    12841 ccacctataa aaatggtgtt agaaaatgga caagaagtaa gtttaattgg acaaatagat
    12901 agagttgatg aatttgaaga aggagaaaat aaatatataa gaataataga ttataagtca
    12961 ggcaataagt ccataagtct aacagaaata tattatggtc tacaattaca attacttgtg
    13021 tatttagatg caatccttga aagtgcaaag gatgaagata taaatataaa tccagctgca
    13081 atactatatt gtagaataaa taatccaata gcaaaattta atgaagataa agatgatgaa
    13141 gaaatacaag aagcaatatt aaaagaactt agaatgaagg ggcttgtagt aaaagactct
    13201 cacatagtta aagagatgga taaatcatta atagatggag aaaggaaaaa ctctttagta
    13261 ataccagtag gtcttactaa ggatggaaat gtaggtaaaa gtacttcagc aataagctat
    13321 gaggatttca aactgcttag aaaatatgta aggcatgcta taaaggattt atgtgaagaa
    13381 atgttaagtg gagaaatacg tatagctcca tataaacata aagatggaac atcatgtgac
    13441 ttttgtgatt actctgctat atgtcagttt gattcaacta taaaagataa caagtataaa
    13501 aatttaaata ataagagtaa tgaagagata ataaaaatga tgaaaggaga tgttaattag
    13561 tgagttctcc taaatggaca aaagagcaat tagaagttat agaaagtaga gaatgcaatt
    13621 tattggttgc tgctgctgct ggttcaggaa aaacagccgt gctagttgag cgtataattc
    13681 aaatgataac aagtagagaa aatccaattg atatagataa gttattagtt gttacattta
    13741 ctaatgctgc tgcgtcagaa atgagagaga ggatagggga tgctatagga aaagccttag
    13801 atgaaaaccc agaaaataaa catttacaaa accaacttgt tttattaaat aaatctagta
    13861 ttacaacaat acactcattc tgtttggatg ttataaaatc aaactttcat agaataaact
    13921 tagaccctaa tttcagaata ggagaccaaa ctgaatgtgc tattttgaaa caagaagcaa
    13981 tagaggaagt atttgaagat ttatatgaag aaagagatga ggggttttta aatttagttg
    14041 aaagttatgc agaaagagga ggagataaag aagtacaaga tattatcttg ggaatatatt
    14101 catttgcaat ggcttctcct gaacctaaaa aatggttgat tgactcagca gaacgattta
    14161 atattgatga aaattttgat ttttcacagt ctatttgggc tagagctata ttagacactg
    14221 taaaaataga gattaatggt ctttgtctaa atatggaaag ggcattaaaa gaagtggaat
    14281 caatagaaga attagaaact tttgcagaaa agttatctgt tgaatataaa aaaattgctg
    14341 acatttcaca agcatgtaat aaatcttggg atgaggcata taaaaagatg gcaagtatgt
    14401 cctttgaaaa ttatgtaaaa ggagtaaaaa gaatttcaaa agatgctcct tcgtatataa
    14461 aagaatcaaa agaaaaggca aaaactataa gagataagac taagaagtct ttagaaagta
    14521 tagtaagtgc tacattcaat aaagataatg attctattag agaagaaata aaatatcttt
    14581 ataacatagt taaaccaata tctagtgttg tactgagatt tgaagaggaa tatagcaata
    14641 agaaaagaga aaaaggaata atagatttta acgatataga gcattttgca ttaaatatac
    14701 ttacagatgt agatgaaaaa ggtaatattg taccttctga tatagcagtt ggatatagaa
    14761 acaagtttta tgaaatattt atagatgaat atcaggatag taatctagtg caggaagtac
    14821 tgcttaaagc tgttgcaaat acagaaactc caaatagatt tatggttggt gatgtaaaac
    14881 agagtatata tagatttaga caagcaaagc cagaattatt tttgcaaaaa tataataact
    14941 ataatgataa aaagggaagt tcccatagaa aaataatgct ttacaaaaat tttagaagta
    15001 gagaagaagt tgtagatgct gtaaattata tatttgaaaa tataatgaat gagaatatag
    15061 gagaaattga atatacagaa aaagaaagac taaatttagg tgcaaatttt aatgtggata
    15121 cagacgagaa atctattatt ggtggagcaa cggagataca cctaatacaa aaagataata
    15181 aacttgatga tgatattata aatgataaag acgatagaat taataacaaa gaagatgaaa
    15241 tagaggaaga agaaaaatta gataatatac aacttgaggc tagaatggtt ggaaacatca
    15301 tcaaagattt aatgaaagtc aatgaagatg gaaaaattca aaaggtctat gataagggaa
    15361 tagatggata tagacctgtg gaatttagag atatagttat tcttttaaga gctacatctg
    15421 catgggctcc agtgtttgca gatgaattga tgaatatgga tataccaaca tatgctgatg
    15481 ttggagtggg gtattttgat acgattgaaa taaaaacaat attgtcatta cttcaaataa
    15541 tagataatcc aatgcaagat atacctctta tatctgtatt aaaatcacct atatttggat
    15601 ttacaccaga ggatttgatt gatattagag ttcagagtaa agataaaatt ttttatgagg
    15661 ttttaaaaag tacagcagag tatgatggat ttacagattc tcaaaatgaa aatgagtctg
    15721 agtttatacc aagtgaagag tgcataaaca aaagtaaaga ttttttaatt aagctaaagg
    15781 aatttaaaga aaagtcaatg tacatgagta cagatgaatt tatatggtac ttgtacacaa
    15841 ggactggata ctatgcctat gttggagcat tgccaggtgg aagtcaaaga caagctaatt
    15901 taaaagtatt gtttgagaga gcaaaacaat ttgaagaaac cagtcttaaa ggaatattca
    15961 actttgtaaa ttttatagag aaattaaaaa aatctagttc tgatatggga agtgcaaaaa
    16021 cacttggtga gaatgcaaat gttgttagaa taatgagtat tcataaaagt aaaggtctag
    16081 aatttccagt agtcatatgc tctgcaatgg gtaaaaattt caatactcaa gattttaaaa
    16141 agagtatttt atatcatcat aatttagggt atggacctca atttgtagac tatgagagaa
    16201 ggatttcttt tccaagtata gccaaagaag cattaaaaag caaaataaat atagaaaatt
    16261 tatcagaaga gatgagagtt ttatatgttg catttacaag agctaaagaa aaattgatta
    16321 taactggttc tactagaaat atacaagata gtataaagag atggtcaaat ggaattgaaa
    16381 gtttagatac aatatcacaa tacgagatat taaaaggtaa aaatttttta gattggataa
    16441 tgccttgtgt attaagacat agggatttat ctaatctact agaagaagta ggattagacg
    16501 cagtttttaa tgttgaacat aattcaaaat ggtatggaaa gttgtggaat aagaatgata
    16561 ttttagtgga aaagaagagt gatgaagaaa aagaaagtat tgaagaaatt cttgaaaaaa
    16621 tagatgtaga taatcctgac agtgattatt acagtgaaat agaagaaaaa ttaaactata
    16681 tatatccata tgaatttagt acaagaaaac ctgctactat atctgttaca gaaataaaaa
    16741 agatacaaaa taattatgaa gaagagttaa taaatactat atttgaacaa aaagtaatat
    16801 taaaaaagcc tctatttatt caaaatgaag aagaaagaga aaaaataagt ggaacagaaa
    16861 gaggtacaat agtccattta gttatggagg ttttagactt aaaaaatgta agtagtgtaa
    16921 atgatataaa atcacaaata agaggttttg tttcaaaagg tataataaca gaaaaacaag
    16981 ctagtatagt aaatccatat aaaatatata aattttttgc ctctaacata ggaaaaagaa
    17041 tgttgaatgc tgaaattata aatagagaaa aatcaattta tgcacaagta aatatgaaag
    17101 acatatatat ttatgaaaag cttataaaca atgacgataa aaaactttat gataatgaaa
    17161 gtgtcatgtt aagaggtata gttgatgctt attttgaaga agataatcaa atagttttgg
    17221 tggattataa aacagatttt gtaaatgagg aaaatataaa tcaaataata gagaaatata
    17281 aaaaacagtt ggatttatat gcagatatta ttgaaacttt aactggtaag tcagtaaaag
    17341 agaaatgtat atatttattt ggagttgatg aagctgtttg ttattagttt ttatatataa
    17401 attaaaccta aaagatagag gaaggggaaa aaatgagatt tattcataca tcagattggc
    17461 atctagggaa gtccctagaa ggccattcta gaattgagga acaagcaaag ttttgtgagg
    17521 aatttataaa aatagtagaa tcaaatgaaa tagatatggt tataattgct ggagatgtat
    17581 atgatacttc taatccacca gcacaagcag aaaaactatt ttatcagact gtatcaagac
    17641 ttgccaataa tggtcagagg tgtgtattaa taatttcagg aaatcatgat aatccagaga
    17701 gactctctgc aataacacct ctagcacatg aacaggggat acttatatat ggttatccat
    17761 taagtgctac gatagaagct aagtataaag ggtttgaaat aacatatgca actcagggat
    17821 gtacaaaact gaatataaat ggagaaaata ttgtggttgc tacattacct tatccaagtg
    17881 aaaaaagatt aaatgaagtt ttttcaagtg aagatgagtt tgagaaacaa aaaaattatt
    17941 ctgaaaaggt aggagatata tttagaagtt tagaagaaaa ttttagaagt gatactataa
    18001 atatagccgt atcacatata tttgtaatag gtggagagag tactgaatca gaaagaccta
    18061 tacaattagg tggaagtttt ttagttgaaa gaaaagattt gccagaaaag gctcaatata
    18121 ctgcactagg tcatttacat aaacaacaaa aagcttccga acgtttaaat gcgtactatt
    18181 ctggttctcc acttcaatat agcaaggatg aaagagcgta taccaaaggg gcatacatag
    18241 tggatataaa agctggtgaa aaaccaataa ttgaagatgt atattttaat aattacaaac
    18301 ctatagaagt atttaaatgt aatggaatag aagaagcact agatatatgt gagcaaaatc
    18361 aagatagaga gatttggtca tattttgaaa taaatactga tgagataata tcacagaatg
    18421 aaattaaaaa aatgaaggaa ctattaaaag acataataga aataaaacca ataataacat
    18481 cttgttatga acaagaaagt gtagatataa aagaaaagtc tatggcagag ttgtttagag
    18541 agttctattc ttttagtaaa ggtgtagagc caaaaggaga acttatggat ttatttctag
    18601 atataataag tgaagaaggt gaatcagcag atgagaccaa ttagattaga acttacaggg
    18661 cttaatagct atattgataa acaagttata gactttgaaa aattaattga aagaggtttg
    18721 tttgggatat ttggaactac tggaagtgga aaatctacaa tattagatgc aataactatt
    18781 gctatgtatg gaaatatatc cagaaataca aaagaatata taaacagtgt gtgcgataag
    18841 gcaattatat catatgagtt tgagatagga agcaaaaaca ctagaagaag atacattgta
    18901 gatagaacca ttgctagaag caaaacagga acaaagacct ctaatgctag attaatagaa
    18961 gtattgaatg acaataccca aaatgtttta gctgataaag ttgtggaagt aaatgaaaaa
    19021 gtagcacagg ttgtaggatt aacggcaaat gattttacta ggtcagtagt tttaccacaa
    19081 gacaaattta atgagtttct aagattatca cgtgcagata gaagagacat gttagagaga
    19141 atttttaatc ttgagaaata tggaagaagt cttggagaaa aagtgaaaaa gagaaaaaat
    19201 atacagttac aaaatttaaa agatttgaaa tcaaaattaa gtcaatatga tggaattaca
    19261 gaggaagtat ataacaatat aaaccaagaa ttaatagagt taaaaaattt ggaaaaagat
    19321 aagaataatg ctttagacct agctcaaaaa tcttatgaag aaagtaaaac agtatatgaa
    19381 gaacaattaa agttagaaaa aaatgaactt agaaaaaatg agcttgattt aaaaaatagt
    19441 gagataaaag aaaagattgc tcttgtagaa aatgatagta acgctaaaaa ggtagaccca
    19501 tacataagtt cagttcaaaa tctagaaaaa aagatagatg aagatagctt cgcagtaagt
    19561 aatttagaaa agaaattagc aatattaaat caggagcttg aagttacaaa aaatagatat
    19621 gaaaaaataa acaaaattaa gaatgaagaa gtccctaaat tgagtgaaga aaaaataaga
    19681 ttgcaacaag caataaaatt agaagaagag ttagttttat tagatagaga gttaaaagag
    19741 ctaaaagaaa gtggaattaa tttaaataag actaaagttg aattagaaaa agtaaagcag
    19801 gtgtcagagt ccagaaaaga tgcagttact aaatctataa aagaagttga aggaaagatt
    19861 gataaagtaa atataagtgc agaattaaaa caaaaaatat ttctagcata tgaatacgag
    19921 aaagattaca acaacgtatt ggaagaaaaa aatcaaaagc taaataaact agaagaaata
    19981 ctcaaagaga cagaaaatat aaatttaaaa gttagatata ttgataaaga taagaatgat
    20041 gtaaatcgta atttagaaaa tttatcactt cacttggatg ttcttcttaa aaaatgtcct
    20101 ggtaagagtg ctgatttact tttaaaatct gaatatgtta ctgaattaag aaataaagca
    20161 aataatacta aagaaaatga aattaagaaa agcagtatac aagatgaatt aaagataata
    20221 cttgaaagta agtttaatac tgaaagggaa gtaaatttac taaatgaaaa acttgaaaat
    20281 aatagaaaga acagagatga cctagaaaaa gaattagaag aactaaagta tttaaattta
    20341 gcctctgaac ttagacgtga attaaaagaa aatatgcctt gtccagtttg tgggtcaaaa
    20401 catcatgaaa atcataatat aactaaatat gatgaaaata tatcttttgt caaagaaaaa
    20461 ctggagaaat tagaaaaaga aaaaataagt ataagaaaca atatagagga attaaatgct
    20521 aaagtaagtg ggtatttatc tatagaaaaa atgaagacta aagaacttga agatgtaaaa
    20581 ggaaaactag gggggattcc atctagtcaa ttattaaaaa aacttgatga agaacaaaga
    20641 aaacttgcat tgttaaaatc taatattcag gagtgggaga aagaaaaaga gagtactgaa
    20701 aataaagtaa cattagcgaa agaagaaaaa aataaaattg aaaaagaaga attaaaaata
    20761 agagagagtc tgaataatta taagaaatta acaagagatt taaacataga aatagaaggt
    20821 ttagaaaata aatgtaaaaa acttaaacag gaatacctag gattaaagac gattactaaa
    20881 gtctctaatc tattgtcaaa agtaaaagaa ataagggaga atgaaaaaga attagaatta
    20941 ctaagtactg ggcattcaaa tttattaaaa aatagagact cactagatat taaaataaga
    21001 gaaaatgaga gtaaactaca tgaaatagag atagaattaa taaaggctag agaattatat
    21061 gtagaaaaga aattgagtag ggataataag tataaagaag ttattagcat aactaaaggt
    21121 gatttagcta aaaatctttt acataatgtt gaagaaaata tatgtaagat attagaacaa
    21181 gaagaatcaa gcaagaaaaa attggaagag caaagattag aatatgaaaa aaacattgct
    21241 gaaaagcaca atatagatgg tagacttaaa actgctaagg aacaatataa agaccaaaaa
    21301 tcaacactaa ataaactatt agcagaaaat aaatttgaaa gtatatatgc agtaaaaaga
    21361 gctttattag atactgatgc agtaaaaaaa ttgattgaag aaatactaga gcatgaagaa
    21421 gaacaaaagt tattatcatt taaaataaaa tcatcaaaag aaaaattaaa tggaagaagc
    21481 ataaagaagg agtactttga acaattaaaa gatgaaattt ataatttgaa agtagaaata
    21541 ggaaatatat ccaaagatat tggagctaat caaaatcagt taataacatt aaaagactct
    21601 ttagataaga taaatgattt taataaacaa cttaaggtag ttgaacacaa tgtggactta
    21661 ttggaagaat tagataaatg tgtacaagga aataaatttg tagaatatgt ttctacaaac
    21721 caattaaaat atatagcgtt ggaagcatca aaacgattgg atggaataac aaaaggaaga
    21781 tatgcacttg aaattgactc aacactaaac tttgtaatga gagataactt taatggagga
    21841 gaaagaagaa gcattgatac tctatctggt ggagagacat tcttgacatc tctatcatta
    21901 gcacttgctc tttcatctca aatacaatta aagggaagtg caccattaga atttttcttt
    21961 ttagatgaag gttttggttc attagatagt gaacttttag aaattgttat agaatccttg
    22021 gaaagattgc atagtaataa tctaagtgtg ggtataataa gtcatgtcga ggaacttaaa
    22081 aatagagttc ctgttaagct attagtttca tctagtgagg ctggaatagg ttcaaaagta
    22141 aaaattgaat atagttagaa aatatatgtt aattgaatat attatctaat atttccaaat
    22201 aatatgtaat tgtgatataa taaaaactaa tattaaagtt atttataatt aatattaata
    22261 taaaaacatg taagtaggag tgtggtaagt gttggaatcg cccaataatt tgattcagat
    22321 tattttttta atagtattac ttatagggtc tgcatttttc tcagcatctg aaacggcctt
    22381 aatgtcgttg agtaaaatca gaatcagata tatgcaagat gaaggagtta aaggagctaa
    22441 gttagtaagt tcattaatag aaaatccaaa taagctttta agttctatat tggttggaaa
    22501 taacgtcgta aatatagcag caacatccat atcaacatct ttgtttatag gattaatggg
    22561 agaaaaagga gtggcacttg ctacagctgt tatgacagta ttagtattaa tatttggtga
    22621 gattactcca aaaacaatag cagcaaataa ttcagaaaag gtttctctat tagtatctaa
    22681 acctataaaa gcaattatat ttatattaag accaatagta tggatattta atataattac
    22741 aaatattata tttaaattat ttggtataac aaataaagga gctaaatcat tcataactga
    22801 agaagagcta aaaactatgg taaatgtaag tcatgaagaa ggcgtccttg aaatggaaga
    22861 gagagaaatc ataaataatg tttttgaatt tggagatatg caagctaaaa atgcaatggt
    22921 acaaagaata gatatggtag ctatagatat ggaagatagt tatgatgaga taatacaggt
    22981 atttaaaact gaaaaattaa gcagaatgcc tgtgtatgaa gaaactatag atgatattgt
    23041 aggaatactt aatataaaag atattatatt tttatctgat gaagaaatag agtcatttga
    23101 tattaaaaat tatatgagag aacctttttt cacgtatgag ttcaaaaaga taacacaact
    23161 tcttgaagag atgaaacttg aaaaaagtca gatggctata gttgtagatg agtatggtgg
    23221 aacatctgga cttttaacta tagaagattt agtagaagtc attgttggag atatagagga
    23281 tgaatatgat gaagaagagg atgaaataca agttataaaa gaagatgagt atattgtaga
    23341 tggaagtact aaaattggtg atgttaatga acttattggt gtaaacttgg aatctgagga
    23401 gtttgattcc ataggaggtt ttataattgg acacctaagc agattgccag aagaaaatga
    23461 agtaattgaa gttgataata taagattttg tatagaaagt atagaaaaaa atagaattaa
    23521 aaaaataaga atatatacat aatgtaataa tgttcttaaa tttattagaa gtgtataaat
    23581 ataaaagata tcttttatat ttatacactt ctttttattt tgtattcaaa taaaactagt
    23641 atgaaatgga caaaataaaa atataaatta gaagaaagga gatttttaag atgagcatac
    23701 tagaaaataa ttttttatac aaattaaaaa acaacactat ctttttttgt atatatacat
    23761 tgttatttat ttttatttac aaagcgtttc catacatagc tccatttttt ctaggtgcta
    23821 taatagcact tatgattaat cctatatcac aaaagttaga aaataagttt catataaata
    23881 aaggtatctc tactcttgtt ctaagttttc ttgcagtggc tatagtcagt acagttacta
    23941 caataatagt aataaattca atgaaagaat taatgggatt tttaaataat atatctgcta
    24001 atcctgagga tataagtaat actattatgt attttttaaa taaaataaat gactttatga
    24061 aatcatttca agaaatagcc aattttgatg tagaacaatt agtaaacaaa ttcagtggtg
    24121 aagtaatgca aattacaaaa aatcttctta ctagtatact tggattggct acttctattc
    24181 catatattat aatatttata attaccttgt ttattgctac gtactttata gcaaaagacc
    24241 ttgataagat tgaaaatagt ttttataata tgtttactgt tgatgttaga aagaaagtaa
    24301 aaaacgtaaa gaaagaggca gggctttcac ttgttggata tataagggcc tatacaatac
    24361 ttatggctat aacatttttt gcaatctggg gaagttttgc tttatttgga ttgaaatacg
    24421 gtctaatagt agggtttgta ggagctttaa tggatttaat tccattccta ggtataataa
    24481 caatatatct tccagtaatt gtttattatt ttcttataaa aaattatttt atagctataa
    24541 gtatgactgt gatatttttt gttttgtctt tgattagaga aatacttgaa cctaaactag
    24601 tatcagtaaa tgttggacta aatccattag ctaccctagc agcgattttt attggaatcc
    24661 aagtaaaagg aataattgga gtaatttttt gtttgggttt ggtatgtatg catgatatac
    24721 ttaagaaggt ggatattttt taattataat aattgataga tttttttaaa aataaaattt
    24781 tattcacagg taaataaaaa aatattaatc ttattaagaa agagggtata tacgtgaaac
    24841 aaaaagtagt ggaaagattt ttaaaatatg tatcatttga tacaacatct aattctcagt
    24901 gtgagaactg tccatcttca gaaggtcaaa gagttttagc taagtatata gttgaagagc
    24961 taaaaacaat gggtgttgat gatgtgagtt tagatgaaaa tagttatata atggctactt
    25021 taaaaggaaa tactgatggt gtggatacta taggattcat atcacattta gatacaattg
    25081 aagatgttag tggaaaagat attaaaccaa gaataataga aaattatgat ggaaaagaca
    25141 tagttttaaa tgaagcgtta aatgttatta cgtatgtaaa ggattctcca gagttggaag
    25201 aatttaaagg tgacgattta atagtcactg atggaacaac tctacttggc tctgatgata
    25261 aagctggtat agctgagata gtgactgcaa tagagtatct aataaatcat ccagaaatta
    25321 agcatggaga tataaaaata ggatttacac cagatgaaga aattggtaga ggtgctgatt
    25381 tatttgatgt tgaaaaattt ggagcaaaat atgcatatac tttagatgga ggaatagttg
    25441 gagaacttga atgtgaaaat tttaatgctg caaatgcaac tattactata catggtagaa
    25501 atgttcatcc aggttcagct aaaaataaaa tggtaaatgc tatacatata gctgctgaaa
    25561 tatcagaaat gttcccagca gatgaaagac cagaaacaac agaaggatat gaaggatttt
    25621 ggcatttaaa ttctataggt ggaaatgtcg agaatgtaag tatggcttat attattagag
    25681 accattgtag agaaaaattt gaaaatagaa aatctattat gatagagaat atagaaaaaa
    25741 taaataagaa atacgataat agagtggaat tggatttaaa agattcttat tacaatatga
    25801 aagaaaagat tgagccagtt atgtttatag ttgatatagc taaagaagct atggaggaat
    25861 taggtataaa accacgttta gttcctgtaa gaggtggtac tgatggagca agattatctt
    25921 ttaatggatt accttgtcca aatatattta ctggtggatt aaacttccat gggaaaaatg
    25981 agtgtatacc agttagttct atggagaaag ctactaaact aattgtaaga atagctgaaa
    26041 aatatgctga aagagtttag ttaaaaggta tttaaaaatt aagcatttaa agttataata
    26101 gctatatcat tctttataag tcaagctgat tataagcttg tgttgtattt aaaatggtat
    26161 agctattttt gtaattattt ttataaaaga taattatttt tagtttaggg tatcaataaa
    26221 aagtatgaat atcaataggt attaacattc aaaaggggga attgtattga aaattaaatc
    26281 taaaaaaata atagcatttg cactttcact tgggattatg ttgccaagtt gtgtatatgc
    26341 agacactatt agtaaaaatc aaaatgcaca ggtagatatg aacaattatc ttcaaggtag
    26401 aaaatctcca aaggaggaaa aacttattgg tgaagataga tttgatacag cgataaaaat
    26461 atctcatagt ggttggaata atggttcaga aagggtgttt ctagttaact caaattcatt
    26521 gccagatgca ttggcttcaa ctcctttggc aagtaaattg gatgcgccaa tactgcttac
    26581 aaataaaaat agtataccat ataatgtaac agaggaaata aaaaggctta atccagcaga
    26641 agttatttta attggaagtg aaggagctat ttcatcaagt gtaaaagaat ctcttgaaga
    26701 tatggaagta ttagtcagta gaatcggtgg agcagataga gaagaaacat ctttacttct
    26761 tactagacag ctagatgata ctggtgattt aggtgtctca aaagtggcag tggttaatgg
    26821 gtataatgga ctggcagatg caacttcaat atcaagccca gctgcaagtg ataatacagc
    26881 tataatatat acaggtaagg atagcataag aagtgaggca aagaatttta ttacacaaaa
    26941 ctcaactaag acatacatag taggtgggga gtacagtata agtaaaaaac ttgaaggaca
    27001 gttagtaaac tcagaaagac tagcagggac agatagaaaa gatactaatg cgaaagtttt
    27061 agaaaagttt tatggaaaat caagtaaggt taataatatg tattttgcaa aagatggaag
    27121 tggtagagaa gctgatttag ttgatgggct tgctgctgga gtattagcat caaaaacaaa
    27181 gtcacctgta gtacttgcaa gtggaagttt aagtagtgca cagaaaagtt ttataaaaaa
    27241 agtaaaggct gataaatttg tacaagttgg tggaggtaaa aatagtaaac catatgcaga
    27301 agcattagcc ttacagtaat attgtgtaaa tcaaaattaa tatataataa tagcaagtaa
    27361 accaagttgc acttcaatat atataataaa ataagtaaac taagttatat ttcagtataa
    27421 tatataataa aataagtaaa ctaagttata tttcagtata atatata
//
LOCUS       DAMJXI010000048        26870 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.050, whole genome shotgun sequence.
ACCESSION   DAMJXI010000048 DAMJXI010000000
VERSION     DAMJXI010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26870
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.050"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(223..1071)
                     /locus_tag="PC465_002581"
     CDS             complement(223..1071)
                     /locus_tag="PC465_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDF2649867.1"
                     /translation="MKNLKIICDSLSDVPKDLLDKYDIDIVSLTVILEEREYKDRIDI
                     SGDEFYKRLREENVYPKTSQATYAQFKEIFEKYTNEDREILYIAGSATATGTYQSAVM
                     AKNDVDGKIYTYDSNLLCMGTGLLVIKAGELASEGKSVAEILPVLDELKEKAFVIFSV
                     DTLEYLQKGGRISSTKAAIGSILNIKPILEIRDGLVSQISQVRGKKNVISKMMELIKS
                     NCGDDLSDQIVYIGYSDDFKEKEQLSKVMQDELRPKEIRFFQIGVCIGAHAGPGVTGI
                     ICLKNK"
     gene            complement(1107..1577)
                     /gene="trmL"
                     /locus_tag="PC465_002582"
     CDS             complement(1107..1577)
                     /gene="trmL"
                     /locus_tag="PC465_002582"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HDF2649868.1"
                     /translation="MSLNIVLVEPEIPQNTGNIIRTCAATGSTLHLVKPLGFSLDDKH
                     LKRCGLDYWDIADIQYYDSFEELQEKYPNSKYFFSTTKAKQSHSDVKYEENCFIVFGK
                     ETKGLPEPLLKANMDTCIRVPMLDVEKARSLNLSNSVAIVVYEALRQIGYPNMR"
     gene            complement(1771..2988)
                     /gene="nth"
                     /locus_tag="PC465_002583"
     CDS             complement(1771..2988)
                     /gene="nth"
                     /locus_tag="PC465_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HDF2649869.1"
                     /translation="MKNVNLKEINEKDVILEEEINKKGMDKKNIIEKEEINKKGIDKK
                     DIIEKKEINKKGIDKKDIIEKKEINKKGIDKKDIIEKKEINKKEMDKKDIIEKEEINK
                     KGMNKKDIIEKEEINEKGIDKMIGKKDEIIDEKDIENFMDIEEDKKSIKVSKKSTKKG
                     ETEKKTKKSSSNKATQKTSKETKSKSKIKNESANEKDVNKILDELEKLYPDAKCELNY
                     GTAFELLIATILSAQCTDVRVNKVTSELFKKYNTARDFANLSIEEISKEIKSCGLYKS
                     KSQKIKDTSEQLCELYDGEVPDSLEKLIKLPGVGRKTAGVVLSNAFNHPAIAVDTHVF
                     RVSNRIGIVDEPNPQKTEFALMEAIPKERWSHSHHVLIFHGRRMCKARNPECASCPIK
                     EDCNYYKELNETK"
     gene            complement(3185..5422)
                     /locus_tag="PC465_002584"
     CDS             complement(3185..5422)
                     /locus_tag="PC465_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2649870.1"
                     /translation="MKYNNTSEINPLDYILGQERAVEAMELGLKINNPAYNIYIAGEP
                     GTGKSTYALKVLNEYASKKNTHKDWCYIYNFENPREPIIVELEKGFGRELKKDMEKLI
                     ESLLEDFKNAFESENFEIEKNKLLDEYEIEKDMLLKQIKKYGEEKGFKLKQSKMGIVF
                     IPLKEEEDESDESDEEFYKAKRELENMAIQVVYKIRNLEEIAEKAVLELEEEIAKLVV
                     EPHIKRLCEKYENYDKIQTYLENIKKDIIEYMYLFYLDEEELKDKYDKEHFIKYKINL
                     FVDNGSSKNKESAPVVVEINPSPANLFGKAEYDYANGNIKTDFTKLLSGAFHRANGGY
                     LVLYADQLLKYTMSWEILKKTLQTKKVILETQTAIKPENMPLDVKLVLIGSHYIYDIL
                     YRYDEDFEKYFKVFVDFDSEMDKNEDNEEGIARFIAYQCDKNNLRHFTKSAVEEVIKF
                     STRLSGDLEKLSTKFNKIMEVVIEGSAYAEFRNSEYTEQCDVKKAISEKRKRINRVET
                     HMDESIENGFTLIETEGRKVGVINGLSVLSTGEYSFGRASRITATTSPGSKGIVNIER
                     EVNMSGSIHNKGVLILGGYLSENFAQDLLLSLNAYVCFEQNYGGIDGDSASSAELYVL
                     LSSLSGVSIKQNIAVTGSINQKGDIQVVGGISEKIEGFYSICKTKGLNGEQGVIIPRK
                     NQRNLVLSDEVNDAVRDGKFKIYTVERVEEAIEILTDVKFEEIKKLVKEKLISFSKIQ
                     TVSKE"
     gene            complement(5528..6442)
                     /gene="queG"
                     /locus_tag="PC465_002585"
     CDS             complement(5528..6442)
                     /gene="queG"
                     /locus_tag="PC465_002585"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HDF2649871.1"
                     /translation="MDNKELKAFCNLIGLNCVGVAGVDKYDNLEKILKDRQQKGYLTG
                     MEEPIIENRINPRNIMKDANSIIVCAFPYHINRQEKNKNSNLSKYCHGKDYHIVVKDF
                     LQQICDYISKTVTDFKYKLFADNGPLVDRYLAYLSGIGYFGINNNIITDEYGSYIFIG
                     YIVNNYKFEEDKPLEKSCFKCGKCVKYCPGNAILGNYDMNPKKCLSYITQKKGDLSEK
                     EKVVLKNGKKVFGCDICQEVCPHNVEIPTTHILEFKENIIDYLDYDEIQNISNKEFKR
                     RYGDRAFSWRGRNIIKRNMEIILDKYDD"
     gene            7524..7928
                     /locus_tag="PC465_002586"
     CDS             7524..7928
                     /locus_tag="PC465_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HDF2649872.1"
                     /translation="MIKITIPGRPISKSNFKLHNINGQAWMPSKGKYSKYLAYENMIA
                     GFINQQYQGETVEENLITVLKLFFPNKRMGDLHNYPKSICDGIEKSGIIKNDKQLKPV
                     LLFDFIDKDNPRVEIELYPVSKYDISYNIFEK"
     gene            complement(8185..9180)
                     /locus_tag="PC465_002587"
     CDS             complement(8185..9180)
                     /locus_tag="PC465_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDF2649873.1"
                     /translation="MRNLGNTNMKIKRVGFGGIPIQRITQDDTNLVINELEKQGINFI
                     DSARGYTISEEAIGIAIEGKRDKFFLATKSMSRDYDSMKRDVEISLNNFKTDFIDLYQ
                     FHNVKEEEYDNLFKDKMAYSALLEAKEQGKIKHIGITSHNLNTIEKAIEDGKFDTIQF
                     PYNIVEGQADEVFKKAHEKGIGIIVMKPLAGGALDNATLAIKYILSKDYIDVVIPGME
                     SVEQVRQNVAVLENLVLDEKDNKEIEEIRNSLGKKFCRRCEYCMPCAVGINIPLSFLC
                     EGYYTRYGLKEWAKEKYEVMDVKPTECIDCGLCESRCPYELPIREMLKTVVEKLG"
     gene            complement(9464..10300)
                     /locus_tag="PC465_002588"
     CDS             complement(9464..10300)
                     /locus_tag="PC465_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HDF2649874.1"
                     /translation="MIKLGTHLSIAKGFANAAETAVYIGANTFQFFSRNPRGGNAKEF
                     DEKDIIKFQEIRKENNFAPLLAHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIE
                     YMCFHPGSHVGGGVDFGIDRIVKGLNNAIKGDENITILLETMSGKGTEIGFKFEQLKS
                     IIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIERLKTVHLNDSMMP
                     FGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDEGHKRELKMIKEILS
                     SK"
     gene            complement(10788..11351)
                     /locus_tag="PC465_002589"
     CDS             complement(10788..11351)
                     /locus_tag="PC465_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2649875.1"
                     /translation="MKEVLVLRDLECIKAIAHPRRIDILKAFDKSPLSAKQLSQLLEE
                     PHAKINYHIKMLYKVGILELVEEKIKSGIVEKYYYPSAKNVVIGNRILNFSLDNGEEK
                     EELYISKFENMSEVFYKAAEEDVLENENIVDYHDISLTHDELVELSDTMKSKIDEILN
                     KRQHNVEGSKYDIAMVIVPTLEEECPS"
     gene            complement(11449..12378)
                     /gene="glsA"
                     /locus_tag="PC465_002590"
     CDS             complement(11449..12378)
                     /gene="glsA"
                     /locus_tag="PC465_002590"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HDF2649876.1"
                     /translation="MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICI
                     IDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMK
                     LEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
                     SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGV
                     DIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMG
                     IGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF"
     gene            complement(13305..14972)
                     /locus_tag="PC465_002591"
     CDS             complement(13305..14972)
                     /locus_tag="PC465_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside kinase"
                     /protein_id="HDF2649877.1"
                     /translation="MKKINLKIEGKDKEYSLEENSPGIRLGDIAKEFCDEHKGYITLA
                     VVDNKLKELNCRVKKDCEINFLDTTNEDGERVYFRVMSFIFVMACREIFWDSRVTIEH
                     SLSDGLYCEVHIDRKLKEADVENIKNKMKEIVNNDYVIEKIEVTRNEAISIFENNEMY
                     EKAELLKYKEYDSAKVYKCRNYIDHFYGYMLPSTGYIKSFDIKLYNGGVIILGPSEED
                     KTLPMKFVPQPKLSSVYYEAEEWSRLMGIDKVVSLNKIIENNEYGDIIRTFEALHEKK
                     LSQIADMIKDGNKRVVLIAAPSSSGKTSFAHRLSIHLRVNNLNPISISLDDYFIDRKH
                     TPLDEYGNYDFESIYAIDLEKFNLDLKKLLAGEEIDDIRFNFKEGKREYTGKKIKIDS
                     NQPIILEGIHGLNPILTSSIPDEDKFKIYISALTQINLDDHNRIPTADLRMIRRIVRD
                     YNFRGYSADNTILQWASVRRGEKKNIFPYQEEADAIFNSACVYELAVLKRFAKPLLEE
                     IKEDNPAHIEATRLLKFLQYFVELDDTSDIPGISILREFIGGSKIVD"
     gene            complement(15046..15801)
                     /locus_tag="PC465_002592"
     CDS             complement(15046..15801)
                     /locus_tag="PC465_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HDF2649878.1"
                     /translation="MAVGIASLLFNIEEALNICESIKQITHLEIGIDNISECSELCKY
                     KDRISKLGLSIGIHLPMELNTCENIEYIRDSWINFIEKIEFELKGFDLRYFNLHLGYV
                     MTNRVRKNRDKYLGNSVDFLDKLNTNSYVCIENTYSKGGDFSNIGNISYDFEYIFKRI
                     KNSKICFCYDTGHCLIDEDAYVKNLKDKIRLIHLSDNDGINDTHVGIGRGILSEEGIK
                     EVLTLDAEYLVLEINYEDIEDTISKLNNIVGEG"
     gene            complement(15811..16347)
                     /gene="lepB"
                     /locus_tag="PC465_002593"
     CDS             complement(15811..16347)
                     /gene="lepB"
                     /locus_tag="PC465_002593"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDF2649879.1"
                     /translation="MNETIKEEIVEWIKIIITALFFAFIITRFIKPTLVNGESMYPTL
                     KSHDYLVANRMTYKLSEPKCGDIMIFKTDLLQENGRKKELVKRVIGVPGDHLKIKDSK
                     VYINGKLLNEVSYIHDNYTEGDIDMVIPKGKVFAMGDNREVSLDSRYKEVGLVDEENI
                     KGKVILRVFPFTDIGIFE"
     gene            complement(16513..17049)
                     /gene="lepB"
                     /locus_tag="PC465_002594"
     CDS             complement(16513..17049)
                     /gene="lepB"
                     /locus_tag="PC465_002594"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDF2649880.1"
                     /translation="MGEAVKKEVVEWIKVIVIALVLAFAITRFIVPTIVKGESMYPTL
                     VERDYLIVNRIAYKVGEPKYKDIIVFKTDLTEENGKKKDLVKRVIGVPGDHVKIQDSK
                     VYVNDKLLDETSYIHNNRTDGDIDIVVPEGKLFAMGDNREKSLDSRYDEVGLVDEHTI
                     LGKVLVRLYPFSKIGTID"
     gene            complement(17149..18459)
                     /locus_tag="PC465_002595"
     CDS             complement(17149..18459)
                     /locus_tag="PC465_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HDF2649881.1"
                     /translation="MTELPKEFLEDIEEILKDEYDDFIKSYEESKTTGLRINTLKIDK
                     KKLFDLELFDLNQIPWAEEGFYYDDKIDRPGRNPLHEAGAYYLQEPSAMSVIPKADIK
                     EGEKVLDMCAAPGGKSTYILSKLNDTGLLVSNEINASRIKALGENLERFGARNCIITN
                     TDSNSLRKTFNGYFDKVIIDAPCSGQGMFRKDEVAISDWSYAKVVECQSIQKEIIRDG
                     YKMLKKDGILIYSTCTFSREENEHVINEFISEYPHAELIEMERLWPHKIKGEGHFVAK
                     IKKLEEEECNVKELKIKNLDKEIKDYREFEKKFLKVDFYSNKKNKFYLRGENLYLLPE
                     IYPDTRKLKVLRYGLHLGVLKKNRFEPSHALSHYLKVEDVKNVENFSVQSESILKYLK
                     GDVVNSNDSRGWVLVSVEGIPLGWGKESSGVIKNHYPKGLRKVF"
     gene            complement(18538..19254)
                     /locus_tag="PC465_002596"
     CDS             complement(18538..19254)
                     /locus_tag="PC465_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HDF2649882.1"
                     /translation="MKLDLFLLAIVPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFL
                     SVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLD
                     GIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
                     KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLE
                     KYMNHSKKVFFGNLRKKKKK"
     gene            19499..20770
                     /gene="sleC"
                     /locus_tag="PC465_002597"
     CDS             19499..20770
                     /gene="sleC"
                     /locus_tag="PC465_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex-lytic protein SleC"
                     /protein_id="HDF2649883.1"
                     /translation="MQDGFLTVSIIDATNNRPIQNAVVNIYSMSNGSQSSSTLYQNLR
                     SNESGQVTGLVLPAPDVDYSLQPSDVRPYSQYIVEAIADGYETVVIEGTQLLATIEAR
                     QGVPMSPRTRSKRSFSRQSELIFDIGEHTLYGTYPPKIPESNLKPLPPPTGFVVLDNP
                     VVPEFIVVHDGLPEDSSAPNYWIPFKEYIKNIASSEIYSTWPEQTIYANVIAIISFTL
                     NRVFTEWYRNKGYNFTITSTTAYDHKFINNRNLFEPINVVVDAIFNTFIKRPPTSRQP
                     LLAQYCDGQKSQCPDQMTQWGSKDLGDQGYDYESILRYFYGDEIVFERAPIVSGVPVS
                     FPGTTLQVGSSGQYVRTIQNQLNAISNSYPAVPKVIEDGIYGTDTENAVKIFQGIFGL
                     PQSGVVDFKTWYEISRVYVATTRIASLNPLI"
     gene            complement(21278..21934)
                     /locus_tag="PC465_002598"
     CDS             complement(21278..21934)
                     /locus_tag="PC465_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649884.1"
                     /translation="MKKGDFIWSGVLICIIAVLAIPSSREVFMEATGAHPYIGGFLKF
                     AVLATMGDLLGARILYKDWKIPVGVFYRAIVWGIIGVVTTYGMSIYSSGVGQAQVDDM
                     LPFEGIAFANALFKSATMNILMSPTVFLFHKVMDCFIDKKYEVGKGIKVKLKDVVNIV
                     DWNAYLGFSVLKTIPFFWIPCHTIVFLFPAEYRVIASAFASIALGLILALANKSKVAV
                     "
     gene            complement(23207..23617)
                     /locus_tag="PC465_002599"
     CDS             complement(23207..23617)
                     /locus_tag="PC465_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649885.1"
                     /translation="MKIKKSLISAMMVSAMVLGGTGAVFANGNDSSNIALPKFESLIK
                     SGITDPTELEKYGVEHYTYEEYAKHIQELKDYAKDPNAVKDVSQKDLEETIKKMEQEL
                     EKIKTEGLKIMKPITIENEDGSQISIAYNYAAID"
     gene            complement(23833..25215)
                     /locus_tag="PC465_002600"
     CDS             complement(23833..25215)
                     /locus_tag="PC465_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HDF2649886.1"
                     /translation="MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLF
                     KLLIPVSLNSGFSIYSIIESTFDVELGNTSTENYTLKKASDSTGKNNSDEFEIMSSIE
                     NIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
                     FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFM
                     LVALVVHWFNPLVWVMFFLLNKDIEFSCDEKVMSILGEEYRADYATTLISLAEENNPF
                     SMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLVFATENKEINEVESF
                     GLTKNEQSDKIGFSISSKSTDLYSPKVESDILVSKAKSDGETHFSTAKVSVIEFREHE
                     ESSMSKVTNSENSEETYVNKSSNSKDVLYTDSGEVSIERSGYNDNRFVISRKGNLLAV
                     NKEQYRTWIE"
     gene            complement(25226..25585)
                     /locus_tag="PC465_002601"
     CDS             complement(25226..25585)
                     /locus_tag="PC465_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2649887.1"
                     /translation="MEIKLFDSELKVMEVLWERGESKAGELVKILKEETGWNRNTTYT
                     VIKKLVSKGAIERIEPNFVCKALISKEEVQKQETETLINKMFGGSSEKFLSAFINKEN
                     LSSDEITKLKQIVEKLK"
     gene            complement(25790..26569)
                     /locus_tag="PC465_002602"
     CDS             complement(25790..26569)
                     /locus_tag="PC465_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HDF2649888.1"
                     /translation="MVSRQELKRVSKAQLSGNWGICAISMAVYIALIVLISIVGLPFE
                     PLTTIVVAVIAFCVSAGFTCMFLKITKDEKVKIGDIFVSGRIYLRSFGFYLFESIIVY
                     IYSFIITIIGAFLSFGVLLTSGAIEYLSSDNVGIGTIISTGITLVLIILVLMLPVYIL
                     LLYVSQATFLICEDKDNMGVFKSMGASLDMMKGNVLKLFVLNFSFIGWYILSIATLGI
                     GLLWLIPYVGVTNCNFYRQLVKENPDVEDILLDKEKSYTMY"
BASE COUNT         8812 a         4931 c         2482 g        10645 t
ORIGIN      
        1 atttttttat atacaattta caagtacatt ttgaaatttt tttaataaat cttactataa
       61 aaaagtgtgc aatagattct tatctattta cacacttccc tacaaactaa atctaatata
      121 tcaacactta atttcataca aaataaatcc aatttaacat ctcaataatt aatattctat
      181 cctaatttaa taaaaaaata aataatgtca cccaaaaata tattatttat tttttaagca
      241 tatgatacca gtaacaccag gaccagcatg tgcacctata cacacaccaa tttggaaaaa
      301 tctaatttct ttaggtctta attcatcttg cataacctta gataattgtt ccttttcctt
      361 aaaatcatca ctatatccta tatacacaat ttggtctgat aaatcatcac cacaatttga
      421 ttttatcaat tccatcatct tagaaattac attcttcttt cctcttactt gagatatttg
      481 cgaaactaat ccatctctta tttcaagaat cggttttata tttaatatac ttcctattgc
      541 tgccttagta gatgatattc tacctccctt ttgtaaatat tccaatgtat ctactgaaaa
      601 tataacaaaa gccttctctt ttaattcatc caaaacaggc aatatttcag caacagactt
      661 tccttcactt gcaagttctc ctgcttttat tacaagtaaa ccagttccca tacaaagcaa
      721 gttagagtca tatgtatata ttttaccatc tacatcattc tttgccatta cagcactttg
      781 atacgtacct gtagctgtgg cagaccctgc tatataaagt atctctctat cctcatttgt
      841 atatttctca aaaatttcct taaattgggc ataagtagct tgagaagttt ttggatatac
      901 attttcttct ctaagccttt tataaaattc atctccagat atatcaattc tatccttgta
      961 ttctctttcc tccagtataa ctgttaatga aactatatct atatcatatt tatctaacaa
     1021 atcttttggc acgtccgata aactgtcaca gattatcttt agatttttca ttaagtatgc
     1081 tcctttctca tttaggcttg ttgaaactac ctcatatttg ggtatcctat ttgtcttaaa
     1141 gcctcgtaca ctacaatagc aactgaattt gataaattta atgacctagc cttttcaaca
     1201 tccaacatag gcactctaat acaagtatcc atatttgctt tcaacaaagg ttctggtaat
     1261 ccctttgttt ctttcccaaa tactataaaa caattttctt catatttcac atctgaatgt
     1321 gactgtttag cctttgttgt agaaaaaaag tatttactat ttggatactt ttcttgtaat
     1381 tcttcaaagc tatcgtaata ttgtatatca gctatatccc aatagtcaag cccacatctt
     1441 tttaggtgtt tatcatccaa tgaaaaaccc agtggtttta ctaaatgtaa agttgaacct
     1501 gttgctgcac aggttcttat tatatttcct gtattttgag gtatttctgg ttctactaat
     1561 actatattta atgacatttt aatcctccct aagtatcgct tttatttatc aaattttatt
     1621 ttataaacag aataacaata atattatact attatataaa ataatgttaa taataatttt
     1681 tatttcatgt atataatagt tttttatcta acattttcac aagtattatt atatcagaaa
     1741 atccctcttg tacaacttac tttctaaaag ttatttcgtt tcattaagtt ctttataata
     1801 attacaatct tcttttattg ggcaacttgc acattctgga tttctagctt tacacattct
     1861 tcttccatga aaaattaata catgatgtga gtgtgaccat ctttcttttg gtatagcttc
     1921 cataagtgca aattctgttt tttgaggatt tggctcgtcc actattccta ttctattgct
     1981 aactctaaat acatgagtat ctacagctat tgctggatga ttaaaagcgt tactaagtac
     2041 aacccctgct gtttttcttc caacaccagg taattttata agcttttcta agctatcagg
     2101 tacttcacca tcatataatt cacatagctg ttcagatgta tcctttattt tttgagactt
     2161 gcttttgtaa agaccacaac tctttatctc tttactaatt tcttcaatgc tcaaattagc
     2221 aaagtctcta gctgtgttgt actttttaaa caactctgaa gtaactttat tcactcttac
     2281 atcagtacat tgtgctgata aaatagttgc tattaaaagt tcaaaggctg tcccataatt
     2341 taactcacat ttagcatctg gatacaattt ttctaactcg tctaaaatct tatttacgtc
     2401 tttttcattt gctgactcat ttttaatttt agacttactt ttagtttctt tacttgtttt
     2461 ttgtgtagcc ttattagaac tactcttctt tgtttttttc tccgtttcac cttttttagt
     2521 acttttttta cttactttga tacttttttt atcttcttca atatccataa aattctctat
     2581 atctttctca tcaattatct catctttttt accaatcatt ttatctattc ctttttcatt
     2641 tatctcttcc ttctcaatta tatctttctt attcattcct tttttattta tctcttcctt
     2701 ctcaattata tctttcttat ccatttcttt tttatttatc tctttcttct caattatatc
     2761 tttcttatct attccttttt tatttatctc tttcttctca attatatctt tcttatctat
     2821 tcctttttta tttatctctt tcttctcaat tatatctttc ttatctattc cttttttatt
     2881 tatctcttcc ttctcaatta tatttttctt atccattcct tttttattta tctcttcttc
     2941 caaaattaca tctttttcat ttatctcttt tagatttaca tttttcataa ttatccccct
     3001 ttaaaatact aatttataaa acctatttat aaatggttta atcatatcaa caaaaaaata
     3061 aacatcaata tataaaacat acaaaataag aatttaattt atatatattt acaaaaaaag
     3121 caaaaaccta ttaaagttct tgctttttat tatacataaa tacccattaa attctataat
     3181 aaacttattc ttttgacaca gtttgtatct tgctgaaaga tattaatttt tcttttacca
     3241 atttctttat ttcttcaaat ttaacatctg tcaatatctc tatagcctct tctactcttt
     3301 caacagtata tatcttaaat tttccatctc gcactgcatc attaacttca tctgataaaa
     3361 cgagatttct ttgatttttt ctaggaatta tgacgccttg ctcaccattt aaccctttag
     3421 ttttacatat agaataaaat ccttctatct tttcacttat accaccaact acttgtatat
     3481 cacccttttg atttatagaa cctgtaacag caatattttg tttaattgat actccactaa
     3541 gagatgataa tagtacatat aattctgcag aagatgcact atctccatct attccaccat
     3601 aattttgttc aaaacaaaca tatgcattta gtgacaatag taaatcctgt gcaaaattct
     3661 cagaaagata gccacctaat ataagtactc ctttgttatg tatagagcca ctcatattta
     3721 cttctctttc tatatttact atgcctttac ttcctgggct agtggtcgct gtaatccttg
     3781 aagctctacc aaaagagtat tctcctgtac ttaagactga caaaccattt atcactccta
     3841 cttttcttcc ctctgtttct attagagtaa atccattttc aattgattca tccatatgtg
     3901 tttccactct attgattctt tttctctttt cacttattgc ttttttaaca tcacactgct
     3961 ctgtatactc cgaatttcta aactctgcat aagcacttcc ttctattaca acttccatta
     4021 ttttattaaa cttagttgat agtttttcta aatcaccaga taatctagtg ctaaatttaa
     4081 taacctcttc aactgctgat ttagtaaaat gccttaaatt attcttatca cattggtatg
     4141 ctataaatct tgctattcct tcttcattat cttcattttt atccatttca ctatcaaagt
     4201 ctacaaatac tttaaaatat ttttcaaaat cttcatcata tctatataaa atatcatata
     4261 tatagtggct tccaatcagt actaatttaa catccaatgg catattttct ggtttaattg
     4321 ctgtttgtgt ttccaatatt acttttttag tctgcaaagt ctttttaaga atttcccaag
     4381 acattgtata ttttagtaat tggtctgcat aaagtactaa ataaccacca ttagccctat
     4441 gaaatgctcc tgataatagt tttgtgaaat cagtctttat atttccattt gcataatcat
     4501 actctgcctt tccaaataga tttgctggac ttgggtttat ctctactaca acaggtgctg
     4561 attctttatt ctttgagctt ccattgtcta caaataggtt aattttatat ttaataaaat
     4621 gctctttatc atacttatct tttaactcct cttcatctaa atagaataaa tacatatatt
     4681 ctattatatc tttctttata ttttccagat aagtttgaat cttatcataa ttttcatatt
     4741 tttcacacaa tctcttgata tgaggttcta ctacaagttt agctatctct tcttcaagct
     4801 ctaacactgc tttttcagct atttcttcta agtttctaat tttatatacg acctgtatcg
     4861 ccatattttc tagttctctt ttagctttgt aaaactcttc atcagactca tcactttcat
     4921 cttcctcttc tttcaaaggg ataaaaacta ttcccatttt actctgtttt aatttaaatc
     4981 ctttttcttc tccatatttt ttaatttgct tcaaaagcat atctttttct atttcatatt
     5041 catccagaag tttatttttt tctatttcaa aattttcact ttcaaacgca tttttaaaat
     5101 cttctaaaag actttcaatt aatttctcca tatctttctt aagttctctt ccaaacccct
     5161 tttctaattc aactataata ggctctctag ggttttcaaa attatatata taacaccaat
     5221 ctttatgcgt attttttttg gatgcatact catttaaaac ctttaaggca taagtacttt
     5281 taccagttcc aggttcacca gctatatata tgttgtacgc tggattattt attttcaacc
     5341 ctaattccat agcttctaca gctctttctt gacccaatat ataatctagt ggatttattt
     5401 cagatgtatt attatatttc aatattcccc cacctcccca tatttaactt taatgatata
     5461 atatgacttt tatacaacaa gtgttaaagt aaatacacat taaagtatat gaaacagact
     5521 cttattatta gtcatcatac ttatctaaaa ttatttccat atttctcttt attatatttc
     5581 tccctctcca gctaaaagct ctatctccat atctcctttt aaattcttta tttgaaatat
     5641 tttgtatctc atcataatcc aaataatcta ttatattttc tttaaattcc aaaatatgag
     5701 ttgttggtat ttcaacatta tgtggacata cttcttgaca aatatcgcat ccaaatacct
     5761 ttttgccatt ctttaaaaca actttttctt tctctgacaa atctcctttt ttttgagtta
     5821 tatatgataa acattttttg gggttcatat cataatttcc caatatagca tttcccggac
     5881 aatattttac acacttacca catttaaaac aacttttttc tagtggttta tcttcttcaa
     5941 atttataatt atttactata taccctataa atatgtaaga accatattca tcagttatga
     6001 tattattatt tattccaaaa tatcctattc ctgataaata agctaaatac ctgtcaacta
     6061 atggtccatt atcagcaaat aacttgtatt taaaatctgt tactgtttta gaaatataat
     6121 cacaaatttg ttgtaaaaag tcctttacta caatgtgata atcctttcca tgacaatatt
     6181 ttgataaatt tgaattttta ttcttttctt gtctatttat atgatatgga aatgcacaga
     6241 ctattataga gttagcatcc ttcattatat ttcttgggtt aattctgttc tcaattattg
     6301 gttcttccat accagttaaa taaccttttt gttgtctgtc cttaagtatc ttttctaaat
     6361 tatcatactt atctacccct gctactccca cacagtttaa tcctattaaa ttacaaaatg
     6421 cttttaattc cttattatcc ataaaattat tcctttttaa tctaattgac tttttaaatt
     6481 tatttatttt ttttagtctt tttaaccttt tctagctatt aactctttta aatacttaat
     6541 ctttttagct attcaatttt cttacctgct taactctttt agatacttcg tctttttatc
     6601 tatttaattt ttttacctac taactctttt aggtacttcg tctttttacc tatttaattt
     6661 tttacctact aactctttta gatacttcat ctttttacct atttagtttt ttacctacta
     6721 actcttttag atacttcatc ttttttattt actaactctt ttaaatactt cgtctttttc
     6781 atttacttat ttaacttttc tatctactta actcctttaa ataattagtc tttttatcta
     6841 tttaattatt ttacctacta actcttttga atacttaatc ttttttattt atttaatttt
     6901 tttatctacc aacgctttta gatacttaat ctttttatct atttaatttt tttatctact
     6961 aactccttta tatacttagc ctttttcatt tacttattta acttttttac ctattaactc
     7021 ttttatatac ttagcctttt tcatttactt atttaacttt tttacctact taactctttt
     7081 agatacttag cctttttaat ctattcaacc ttttttaccc acttaacctt cttacctttt
     7141 aatataaact ctaaaacttc aaatatcatt agttatattt tgacattctt cctatagtta
     7201 atgcaaaaag attgattttt tcttataatt aatatcccat ttacattgcc atttattaag
     7261 tctttacttg acttatatgg atttcttttt actctcttta ctaaactata cttattaata
     7321 ttatgaaggt cttataatag tctaatatga atatgtccat catatatcaa attttaaaat
     7381 ttgtaagcaa aatacttatc ttatattact acatctaaag tggaaaattt tacaaacaag
     7441 ctctgtaaaa acactttaaa taacaatttg cttttaaatc atatacagat tataataaat
     7501 actgtataag gatggtgaaa aatttgatta aaataacaat tccaggtaga cctattagta
     7561 aatctaattt taagcttcat aacataaatg gtcaagcatg gatgccttca aagggaaaat
     7621 attctaagta tcttgcatac gaaaacatga ttgcaggttt tataaaccaa cagtatcaag
     7681 gggaaactgt tgaagaaaat ctaataacag tcttgaaatt attcttccca aataagagaa
     7741 tgggggattt acataattat ccaaaaagta tttgtgatgg tattgaaaaa agtggaataa
     7801 taaaaaatga taaacaactt aagccagtac ttttatttga ttttatagat aaagataacc
     7861 ctagggttga aattgaactt tatccagtat ctaaatacga tatatcctat aatatttttg
     7921 aaaaataaag attttatgtg ttattcgaca ttatattgat actccagtat ttgaaactat
     7981 actaatacaa caataataat tgtgttatgt ctatactcaa acaaatgttt ttaaaaagca
     8041 ttaagtaaat atttaataag tattaaacaa atattaaatt tatataatag ctataactat
     8101 gtaaatttaa tatttgtata taagaccaca tctaataaaa agaaatcgga gtaaatttaa
     8161 tacaccgatt tcaataaata aaatctatcc tagcttttca acaacagtct taagcatttc
     8221 tcttatagga agttcatatg gacatctact ctcgcaaagc ccacagtcaa tacactcagt
     8281 aggtttaaca tccataacct catatttttc tttagcccac tcttttaatc catatctagt
     8341 ataataacct tcacataaaa aactcaatgg tatatttatt cctacagcac aaggcataca
     8401 atattcgcat cttctacaga attttttacc taaagaattt cttatttctt caatttcctt
     8461 attatctttt tcatctagca caagattttc aagtacagcg acattttgtc taacctgttc
     8521 aacactctcc atacctggta taactacatc tatgtaatct ttagatagta tatatttaat
     8581 agccagtgtt gcattgtcta aagcacctcc agctaaaggt ttcattacta ttatcccaat
     8641 tcctttttca tgagcttttt taaacacttc atctgcttgt ccttcaacta tattgtaagg
     8701 gaattgtata gtgtcaaatt ttccatcttc tatagctttt tctatagtat ttaaattgtg
     8761 actagttata ccaatatgtt ttatcttacc ttgctccttt gcctctaaaa gggcactata
     8821 agccatttta tctttaaaaa gattatcata ctcctcttct ttaacattat ggaattgata
     8881 taaatctata aaatcagttt taaaattatt taaacttatt tcaacatctc tcttcattga
     8941 atcataatct ctggacatac ttttagtagc taagaaaaat ttatctcttt ttccttcaat
     9001 ggcaattccg attgcttcct cacttattgt ataccctctt gcactatcaa taaagtttat
     9061 tccttgtttt tctaactcat ttataactaa gttagtatca tcttgagtaa tcctttgtat
     9121 tggaatgccc ccaaagccaa ctctctttat tttcatgtta gtattgccta aatttctcat
     9181 atctttcccc acctaacttt taataatttt ttatataata taaatatgtc atctttaatt
     9241 atacaacaaa ttatgagaat ctttgcaata tatttacata ctattcataa tataattata
     9301 ttttatatca gtctattcat aatataatca tactttatac ccagttaatt tgtatacaat
     9361 ttttgttatt cctatccatt aatttaaatt atcacatttg ataattgtat ctccacccta
     9421 attatgttga gggcggagta tttcacatat ttttaataaa ggtttattta ctagatagta
     9481 tttcttttat cattttaagc tctctcttgt gaccttcatc atcaaaagga gtttctaaga
     9541 aaaatggtaa atgttttaga ctaggatgtt ccataaaatc aattaatgct tttaatccta
     9601 tctttccttc ccctatagga gcatgtctgt cttttttgtc tccaaatggc atcatactat
     9661 catttagatg gacagttttc aatctttcta tgcctataac cttatcaaat tcttccaaaa
     9721 ccccatctaa atcattcact atatcataac cagctgaaaa aatatgacat gtatcaagac
     9781 acacacctat tttttcttta tgctcaattt tgtctattat actttttaat tgctcaaatt
     9841 taaaacctat ttcagttccc tttcccgaca tagtttcaag aagtatagtt atattttcat
     9901 caccctttat ggcattgttc aatcctttta ctattctatc tatgccaaaa tctacaccac
     9961 cacctacatg acttccagga tgaaaacaca tgtattcaat tcctaatgag tccatccttc
    10021 ttatatcctc atctatcacc cttgttgcaa attcgtatac atcatccttt gtaccaccca
    10081 gattcatagt atatggtgca tgtgcaagca gtggtgcaaa attattttct tttctaattt
    10141 cttgaaattt aattatatct ttttcatcaa attctttagc atttcctcct cttggatttc
    10201 tactaaaaaa ttgaaatgta tttgcaccaa tatatacagc tgtctcagcc gcattagcaa
    10261 atccttttgc tattgaaaga tgtgttccta atttaatcat attaatctcc ttttatttgt
    10321 actactactt gtactcaatt ttaattttga actactccac cttaactaca tttagccaac
    10381 atatgaagat ggagattcct atttgatagt actttttcac taaaaattca taagctctaa
    10441 gggatgttct atcccaacta atctcattcc tcttttaaca tatttctagc attgatttaa
    10501 tttatattaa tttttaattt taatatttac actttaatta tacccatttt aatcaatttc
    10561 aaatattata atcttacata ctttgtatat tatctaagca cttctcagat agtgtataca
    10621 tcttatacta tacatattat ttacaaatac aataggtata agaaaacaaa aaaatagaga
    10681 ttaaaaatca ttgttttacc cataccaaaa actatttttt gattattaag taaattttga
    10741 tgttcaatct ctaatattat atctttaatt aatccataat taattctcta actaggacat
    10801 tcctcctcaa gagtaggaac tataaccata gctatatcat acttagaacc ttcaacattg
    10861 tgttgtcttt tatttaaaat ttcatctatc tttgacttca tagtgtcact aagttcaact
    10921 aattcatcat gagtaagaga aatatcatga taatcaacta tattttcatt ttctaaaaca
    10981 tcttcctctg ctgccttata aaaaacttca ctcatatttt caaattttga tatgtacaat
    11041 tcttcttttt cttccccatt gtctaaagaa aaattaagta tcctattccc tataaccaca
    11101 ttttttgcac ttggataata gtacttttcc acaatccccg actttatttt ttcctcaact
    11161 aattctaaaa taccaacttt gtataacatt tttatatggt agtttatttt tgcatgaggt
    11221 tcttccaata attgagataa ttgttttgct gacaatggcg atttgtcaaa tgcttttaga
    11281 atatctattc tacgtggatg cgcaatagcc tttatgcact ccaaatctcg taataccaat
    11341 acctctttca ttgacccctc ctaaaaaatt tatttaattc atatttcttt acaatttaat
    11401 tatatattaa attatatgtt gttgtcaaaa aaatcctttc ttaatatttt aaaaaatatt
    11461 taatttgagt ttatttgaca actcctctaa aactttaact cctgcgacgc tgttaccttt
    11521 tttgtcaagc gcaggtccat aaacaccaat ccccatgcgt cccggcacag aagccattat
    11581 accaccccca actccagatt ttgcaggaat gccaacttta atagcaaatt ccccagaagc
    11641 atcatacatt ccacaagtca tcataaatgt cttgacaatc ctagaaacca tttcactcat
    11701 taaatgctca ccattttcta tatctactcc ataatttgca agatttattc caattctcgc
    11761 taaatctaca gaatctatct caattgagca ttgtttaaaa taaaggtcta gaacatcttc
    11821 tacattccct ctgataaatc catcactttt caataagtaa gccatagctc tgtttctatc
    11881 tccagtcatt ttttcagact tatagacatc atagtttatt cctatattat cattttttgc
    11941 taactttcta aagaaactaa gcattctttc ttctttttct tctaaacaac tcccatttat
    12001 aagggaagtg gttactatag cccctgcatt tatcattgga ttacagggtt tttttgtgtc
    12061 attaatttca agtttcatta ttgaattaaa tgggtcccca cttggctcca ttccaacgtt
    12121 tgaaaaaacg tcttcccaat cattatccat aagtgccata gcaagcacaa ttggttttga
    12181 aatactttgt atagtaaact ttgtgctaca gtttccagca ctataaagat tattttcgct
    12241 atctatgata caaattccta aatcatttct tctagcgttt tttaattctg gtatgtaact
    12301 agcgacttgt ccataattag tatacttctt attagaactt ataatttctt ttaataatgt
    12361 ctcatctaac gtattcatat gcacctctta tattatgtta tatattctat tttagcacaa
    12421 gtttatacta taataaaaca atgttaaaaa aaattatact ttaaaattat tttctacaag
    12481 aatcaattca tttttcaaac aatttaaata gtttaaagag cttaataatt tagtaattca
    12541 ataatttaac aacctagcaa tttagtaatc taataatcca gtaatttaac aacctaataa
    12601 tttagcaatc taataatcta actatctaat aatccagtaa cttaacaacc taataattta
    12661 gtaattcaac aatctaacaa ttcaataatt taacaaccta gtaatctaac tatctaataa
    12721 tccagtaact taacaaccta gtaatttagt aattcaacaa tctaataatt caataattta
    12781 acaacctagt aatctaacta tctaaataat ccagtaactt aacaacctag taatttagta
    12841 attcaacaat ctaataattc aataatttaa caacctagta atctaactat ctaaataatc
    12901 cagtaactta acaacctagt aattcaacaa cctaataatt caataattta acaacctagt
    12961 aatttagcaa tccagcaatc taataatcca gtaatttaaa tttttataac accaaaaatt
    13021 tctaacccaa caccttttac tcttttactc ttttactctt ttactctttt actcttttaa
    13081 aaaataatca cataaactaa caaaatatta aacaaaaaag taaaatttaa aataaaaagc
    13141 ttgcttcata caaaagtata aaacaagcct ttttatatat caactcaaac tttaaaatct
    13201 gtatcaattt aattctccac tttacactta atatacttaa cataaaccaa tcacactact
    13261 tgctatgcca tttaatcttc ataaaacaat ctataataca catattaatc aactatttta
    13321 cttcctccaa taaattccct aagaattgaa atacctggta tgtcagaagt atcgtccaat
    13381 tcaacaaaat actgcaaaaa ctttagtaat ctagtagctt caatatgtgc aggattatct
    13441 tcctttatct cttccaacaa aggtttcgca aatcgtttta aaactgccaa ttcatataca
    13501 caagcagagt taaatatagc atctgcctcc tcttggtacg ggaatatatt cttcttttct
    13561 cctcttctaa ctgatgccca ttgtaaaata gtattatcag cactatatcc tctaaaatta
    13621 tagtctctaa caattcttct tatcattctc aaatcagcag tagggattcg attatggtca
    13681 tccaaattta tttgagtaag ggcacttatg tatatcttaa atttatcttc atctggtata
    13741 gatgatgtta aaataggatt tagcccatgt ataccttcta atataattgg ctgatttgaa
    13801 tctatcttta tctttttacc agtgtattct ctcttacctt ctttaaaatt gaatcttata
    13861 tcatcaattt cttcaccagc taaaagtttc tttaagtcta agttaaactt ctctaaatct
    13921 attgcataaa ttgattcaaa atcataattt ccatattcat ctaaaggagt atgttttcta
    13981 tctataaaat aatcatctaa agaaattgaa ataggattta aattatttac tctaagatgt
    14041 attgataatc tgtgagcaaa acttgttttt ccagatgaag atggagctgc tattaaaact
    14101 actctcttat tgccatcctt tatcatatcc gctatttggg ataacttctt ttcatgcaat
    14161 gcttcaaatg tccttattat atctccatat tcattgtttt ctattatttt attaagagat
    14221 actaccttgt caattcccat aagtcttgac cattcttctg cttcataata tacacttgat
    14281 agcttaggtt gaggtacaaa tttcatagga agagtcttat cttcttcact aggtcctaaa
    14341 attataacgc ctccattata aagcttaata tcaaatgatt ttatataacc agttgatggc
    14401 aacatataac cataaaaatg gtctatatag tttctacact tatatacttt agcactatca
    14461 tactctttgt atttcaaaag ctctgccttt tcatacattt cattattttc aaagatagaa
    14521 atagcttcat ttcttgtaac ttcaattttt tctataacat aatcgttgtt tactatctct
    14581 ttcatcttgt tttttatatt ttcaacatct gcttctttaa gctttctatc tatatgaact
    14641 tcacaatata gcccatctga tagtgaatgt tctattgtaa ctctgctatc ccaaaagatt
    14701 tctctacatg ccattacaaa tataaatgac atgactctaa agtaaactct ctctccatct
    14761 tcattagtag tatctaaaaa atttatctca caatccttct taactctaca atttagctct
    14821 tttagtttat tgtctacaac tgcaagtgtt atataaccct tatgctcatc acaaaattct
    14881 tttgctatat ctcccaatct gattccaggg gaattttctt ctaatgaata ttccttatct
    14941 tttccttcta tttttaagtt tatttttttc acttcaacat ctccttcctt ttgatgaata
    15001 taaattttaa ttaatgaggc atatcaacaa gataaagaga ggtatttaac cctctcctac
    15061 aatattattc aatttactta tagtatcttc aatgtcttcg taatttattt ctaatactaa
    15121 atattctgca tctaatgtta agacctcttt aatcccctct tcagataaaa ttcctcttcc
    15181 tataccaaca tgtgtatcat tgataccatc attatcactt aagtgtatca gtcttatttt
    15241 atcctttaag ttctttacat aagcatcctc atcaattaaa cagtgtccag tatcgtaaca
    15301 aaaacaaatc ttagaatttt taatcctctt aaatatatat tcaaaatcat aagatatatt
    15361 tccaatattt gaaaaatccc caccttttga ataagtattc tctatacata catatgaatt
    15421 tgtatttaat ttatctaaaa aatccacact atttcctaaa tatttgtctc tattctttct
    15481 aactctattt gtcataacat atcccaaatg aaggttaaaa taccttaaat caaatccttt
    15541 tagttcaaat tctatcttct caataaaatt tatccatgaa tctcgtatat actctatgtt
    15601 ttcgcaagta tttaattcca taggcaaatg tatccctata gataatccta acttagaaat
    15661 tctgtcttta tatttacata actcactaca ttcagatata ttgtcaattc caatctctaa
    15721 atgagttatt tgctttatac tctcacaaat gtttaaagcc tcctcaatat taaacaataa
    15781 ggacgctata ccaactgcca tacaaatcac ctactcaaaa atacctatat ctgtaaaagg
    15841 aaatactctt aaaataactt ttcctttaat attttcttca tctactaatc ccacttcttt
    15901 atatctactg tctaaactaa cttctctatt gtctcccatc gcaaatactt ttcccttagg
    15961 aatcaccata tcaatatcac cttcagtata attatcatgt atatatgaaa cttcatttaa
    16021 taacttacca tttatataaa ccttagaatc cttaattttt agatggtcac caggaacacc
    16081 tataaccctt tttacaagct cttttttcct tccattctct tgtaataaat cagtcttaaa
    16141 tatcattata tctccacatt ttggttctga taacttatat gtcatcctgt ttgctaccaa
    16201 ataatcatgt gatttaagtg ttgggtacat tgattctcca tttactaatg ttggttttat
    16261 aaaacgagtt ataataaatg caaaaaaaag tgcagtaata attattttta tccactctac
    16321 aatctcttct ttaatagttt cattcattca caaattctcc tttatagtta tattatcttt
    16381 attgataatg tctcttaaac actatctttt agataagtct actaaataag gtgttgtctt
    16441 ttttatatag acaactattg tgtatggtct ggtgatttca gctaatcagc gattgctcca
    16501 aattttatat gtttagtcaa tagttcctat cttagaaaat ggatacaatc tgactagaac
    16561 ctttcctaaa atggtatgct cgtcgaccaa tccaacctca tcgtatctac tatctaaact
    16621 tttttctcta ttatctccca ttgcaaataa ttttccttct ggaactacga tatcaatatc
    16681 tccatcagta cgattattat gtatatagga agtctcatct aacaacttat catttacata
    16741 taccttggag tcttgtattt ttacatggtc accaggaacc ccgataactc tttttactaa
    16801 atcttttttc tttccatttt cctctgttaa gtcggttttg aatactatta tatctttgta
    16861 ttttggctct cctaccttgt acgcaattct gttaactatc aaataatcac gttcaactaa
    16921 tgtaggatac attgattctc ctttgactat tgttggcact ataaaacgag ttattgcaaa
    16981 tgccaaaaca agagctatga caatcacttt tatccattct acaacttctt ttttaactgc
    17041 ttcacccact aaaatcgtct cctctgtgtt aaatattaag tcaatctaca gcaaaataat
    17101 ctaccataaa cctacaatat aaatattata cttctttttt ctaatagttt aaaatacttt
    17161 tctaagacct ttaggataat gattcttaat tacaccagaa gattcttttc cccaacctaa
    17221 aggtattcct tcaaccgaaa ccaaaaccca tcctctacta tcattagaat ttacaacatc
    17281 cccttttaaa tatttaagaa ttgattcact ctgtacactg aagttttcaa cattttttac
    17341 atcttcaact tttaagtaat gagatagtgc atgagaaggc tcaaatctat tcttctttaa
    17401 aacccctaaa tgcaaaccat atctcaatac ttttagtttt ctcgtatctg gatatatttc
    17461 aggaagtagg tacaaatttt ctcctcttaa ataaaattta ttttttttat tactataaaa
    17521 atcaaccttt aaaaatttct tttcaaactc cctataatcc tttatttctt tatctaaatt
    17581 ttttattttt aattctttga cattacattc ttcttcttct aattttttta ttttggcaac
    17641 aaaatgacct tctcccttta tcttatgagg ccataatctt tccatttcaa taagttctgc
    17701 atgtggatat tcactgataa actcatttat aacatgctca ttttcctccc ttgaaaaagt
    17761 acaagttgag taaattaaaa tgccatcctt ctttaacatt ttatatccat ctcttataat
    17821 ctctttttgg atggattgac attctactac ctttgcataa ctccaatctg atatggcaac
    17881 ctcatccttc ctaaacatac cttgcccaga acaaggtgca tctataataa ccttatcaaa
    17941 atacccatta aacgtctttc ttaagctatt agaatcggtg tttgttataa tacaatttct
    18001 cgctccaaat cgctctaaat tttcccctag agccttaatt ctactagcat taatttcatt
    18061 agaaaccaat aaacctgtat cgtttagctt agatagtata tatgtagatt ttccaccagg
    18121 agcagcacac atatcgagaa ctttttcacc ctctttaata tctgcctttg gtattacact
    18181 cattgcagaa ggctcttgca aatagtatgc tccagcctca tgcagtggat ttctaccagg
    18241 tctgtcaatt ttatcatcat aataaaaacc ttcttctgcc catggtattt gattcaaatc
    18301 aaacaactcc aaatcaaata attttttctt gtcaattttt aaagtattta ttctaagccc
    18361 agtagtctta ctttcctcat aactttttat aaaatcatca tattcatctt ttagtatttc
    18421 ttcaatatct tctaaaaatt cctttggtaa ttctgtcaaa tctataatcc cccttcaatc
    18481 tgctttactt gtgtgtcatt tattatactt taattattta tgtctttcct ttaaatttta
    18541 tttcttcttc tttttcctaa gattaccgaa aaacactttt ttagagtgat tcatatattt
    18601 ctcaagttta tcaagattta tcttccacaa aattattaca taaactataa gtaatataat
    18661 agcccatcta tattctatca tcaatatgaa atcaaaaact ccatgtaata aaattggaat
    18721 taacactgcc ataaacaaat actcacgtct tttattttta tttccctcaa atttatactt
    18781 agaaatatag tagcccatag taattgcaaa cattacatga gctggtatag agataactgc
    18841 cctattaata ccaacttgca gtgctagatt tctactttca gaaaaaatat aaaccatatt
    18901 ttcaattgtt gcaaatccta aagctaaaaa tacagagtaa ataataccat ctaacttttc
    18961 agtaaagtgt ttttctttaa ttagggcagg aatcagtatc agagctttta caccttcttc
    19021 tacaagtcct gcaactacaa atgatacata tattagttct gaataccctt caaatacatt
    19081 aaacttcatc agtaaatttt ctaaaagtat aattataaca cttagaaaag cacctattaa
    19141 aaaaaattta attagatgga ttaggggttc tctgcaatat ctatctttag accttatcca
    19201 aaacatccct atcaatatag gaactattgc taataaaaat aaatctagct tcatagatta
    19261 ttttcctttc aaaatttttg atttatttat gatttatatc atctacttat ttttaactta
    19321 ttcgtgtttt aaatacatac taaaatatac attaaattat tttaaattat ttaaatacaa
    19381 atatactcaa atactcaaaa aaatttaaat ttatatctat attatttaac aaatttcaag
    19441 ctatattcat atcttgaaat ataagggaac taaattcatt taaagaaagg gtgatttgat
    19501 gcaagatggt ttcttaacag taagcataat tgatgctact aacaatagac ctattcaaaa
    19561 tgcagtagta aacatatatt caatgtctaa tggtagccaa agctcatcaa ctttatacca
    19621 aaacctaaga agtaatgaat ctggtcaagt gactggttta gtattaccag caccagatgt
    19681 agattactct ctacaaccat ctgatgttag accttatagc cagtatatag tggaagccat
    19741 agcagatgga tatgagacag ttgtcataga aggaacacag ttgttagcta caattgaagc
    19801 aagacaagga gttcccatgt ctcctagaac aagaagtaag cgttctttct caagacaaag
    19861 tgagttgatt tttgatatag gagaacatac tctatatggt acttatcctc ctaagattcc
    19921 agaaagtaac ttaaaaccat tacctcctcc tactggtttc gttgtattag ataaccctgt
    19981 agtgcctgaa tttatagtag ttcatgatgg tttgccagaa gattcatcag ctccaaacta
    20041 ttggattcca tttaaagagt acattaaaaa catagcgtca tctgaaatat attcaacttg
    20101 gcctgaacag acaatttatg caaatgtaat agctataata tcatttactt taaatagagt
    20161 ctttactgaa tggtatagaa ataaaggata taactttaca ataacttcaa caacagcata
    20221 cgaccataag tttataaata atagaaactt atttgaacca attaacgtag ttgtagatgc
    20281 tatttttaat acttttataa aaagacctcc tacatcaaga cagccactat tagcacaata
    20341 ttgtgatgga caaaaatccc aatgtcctga ccaaatgact caatggggca gtaaagactt
    20401 aggtgaccaa ggatatgact atgagagtat actaagatat ttctatggag atgaaatagt
    20461 atttgaaaga gcacctatag taagtggtgt accagtgtca ttccctggta ctacactaca
    20521 agttggttct tctgggcagt atgttagaac catacaaaat cagttaaatg ctatatctaa
    20581 ttcttatcca gctgtaccaa aagttataga agatggtatc tatggaacag atacagaaaa
    20641 cgctgttaag atattccaag gaatctttgg tttacctcaa agcggagtag tagattttaa
    20701 aacatggtat gaaatatcca gagtttatgt agctacaact agaatagctt ctttaaatcc
    20761 tttaatttaa agcttgattt agaacataaa ctcaaattat tgaataaaat tattaattta
    20821 aaataaaaat ggctgttatg aactaatata taccataagt attacttata agtattgtag
    20881 tcttaacagc cattttttag ttataacttg tttttttaga atcttaaaac tttaaatggg
    20941 ggattttaag cttcttaaaa acagtgctta gcaacttaga tttctttaaa atattatatt
    21001 tatttttaag tttaataaaa tgctattcta acgaaaaacc tactttttat ttaaaatctc
    21061 acttattatt taaaatgcta cttctcactt agagtattac tccttattat ttaaaacact
    21121 atctatcact tagaatatta cttcttatta tttaaaacac tatccatcac ttagaatatt
    21181 acttcttata taaattatta tttattataa atacaaataa tattaattta aaaagttatt
    21241 cctaatttaa ataatactac tatcttcatc agtgaaccta aactgcaact ttagacttat
    21301 tagctaaagc caatattaga cctaaagcta tagatgcaaa tgcagaagca attactctat
    21361 actcagcagg gaataagaat acaattgtat gacatggtat ccagaaaaat ggtatagttt
    21421 ttaaaacact aaaaccaagg taagcattcc agtccacaat atttaccaca tctttaagtt
    21481 ttaccttaat cccctttcca acctcatatt ttttatctat aaaacagtcc ataaccttat
    21541 ggaataaaaa tacagttggt gacattagta tattcatagt tgcactctta aatagagcat
    21601 ttgcaaaagc tattccctca aatggaagca tatcatccac ttgtgcttga cctacacctg
    21661 atgagtagat tgacattcca tatgtggtaa ctacacctat tattccccaa actattgctc
    21721 tataaaatac tcctactggt attttccaat ccttatacaa aattctagca ccaagtaaat
    21781 ctcccattgt agctaataca gcaaacttta aaaaacctcc aatatatgga tgtgcacctg
    21841 ttgcttccat aaatacttct ctactacttg gtattgctaa gacagcaata atacaaataa
    21901 gaactccact ccatataaaa tcgccttttt tcatatttat aaatactatt taatatataa
    21961 atagttctcc tttctattaa agatttattt aatttacaat ctatctacaa ttatttatta
    22021 atcacttatt attagatatt cattttccat atttaaattt attctatccc tttatctatt
    22081 tattttctta ctactctatc caccattatc tatatattta ttttacgatt actctttcac
    22141 cctaaccctt taattatcta tttttttctg atattcttat ctaccatcat ccatatattt
    22201 attttacgat tactctttca ccctaaccct ttaattatct attttttctg atattcttat
    22261 ctaccatcat ccatatattt attttacgat tactctttca ccctaaccct ttaactatct
    22321 attttttctt actattctta tccacatcat ccatatattt attttacgat tactctttca
    22381 ctctaaccct ttaactatct attttttctg atattcttat ccaccatcac ccatatattt
    22441 attttacaat tactctttta ccctaaccct ttaactatct atttttttct ggtattctta
    22501 tctactatta tctgtatatt tattttatga ttactctttt aacctacccc ctatacttta
    22561 tagtaatatg tttttaacct ttttcattat tcccaatatg ctttataact acaaatactc
    22621 tcccccctta aaaataataa taaaattaat caataaattt ataatcatat tattactcta
    22681 tgtattaagc aattactatg ccaataaact ttgatttttt taaacaaatc ttaaaaatcc
    22741 taaaatgcta attttcttta acttttaatg aatctaatag ataacattta attttcgtta
    22801 tatttttcag aatatttcta ttattatttt taagaaaaaa aaataatgtt aacatttctt
    22861 aacatacatt aaaaaatgtt aacattataa attgggttta atacttttac tttgactcga
    22921 tttactttta ttctacttct tactttattt ttaacttaga ctttattttt ttattactta
    22981 tttgagtctt atttatttta ttctcactcc atatgttcaa ttacatttgt ctaaattctt
    23041 tgatactttt attacataat tttaacaagc ttaagtgtta tttgggtagt gcagttgata
    23101 attatttaaa taatcatcaa ctgcatgttt atatcattac agtagcttaa tgtatttaat
    23161 catacttact taggattttg aaatatctta gagattatat ttaacattag tcaattgctg
    23221 cataattgta agcaattgaa atttgagacc catcttcatt ttctatagtg ataggcttca
    23281 taatttttaa tccttcagtt tttatctttt ctaattcttg ttccattttc ttaattgttt
    23341 cctcaaggtc tttttgactt acatctttga ctgcattagg gtctttagca tagtctttta
    23401 attcttgaat atgtttagca tactcttcat aagtataatg ctcaacacca tacttttcca
    23461 attcagtagg gtcagttatt cctgatttta ttagagattc aaatttaggt aaagcaatat
    23521 tagatgaatc atttccattt gcaaatactg ctccagttcc tcctagtacc attgcagata
    23581 ccatcattgc acttataagg gattttttta ttttcataac caatcttcct ttcttagaga
    23641 tttatttggg tagtgtagtt taaaatgact attgcaatag ttatcaacta cactcttaga
    23701 ctatcacagt agtcatgttt atgtcaagcc tttttaaaaa acttttcaat aaaaaatact
    23761 atctcaaagc aaaattaatt attttgagat agtattttaa ttctaaatct tttatattac
    23821 taagatttat ggttattcta tccatgttct atattgttct ttattaactg ctaacaaatt
    23881 cccttttctt gatatgacaa agcgattatc attatagcca cttcgctcaa ttgaaacttc
    23941 tcctgaatca gtataaagta catccttact attactagat ttatttacat acgtttcttc
    24001 actattctca gaattagtta ctttgctcat agatgattct tcatgctctc taaattcaat
    24061 tacagatact tttgccgtac taaaatgagt ctctccatca cttttagctt tactaacaag
    24121 aatatcagat tctactttgg gagaatataa atcagttgat ttactactta ttgaaaatcc
    24181 aattttatca ctttgttcat tttttgttaa accaaaagat tcaacctcat taatctcttt
    24241 attttctgtt gcaaaaacaa gacctgtccc acaaactaat acagttgaaa ctaaaaaagt
    24301 aacataagtt gattttttaa atttcataat attaactatt ctcttttcta tttttgtctt
    24361 tccaaatcca ctacatattg tcattgaaaa tggattattc tcctctgcta gacttattag
    24421 tgtggttgca taatcagccc tatattcttc accaagtata ctcataacct tttcatcaca
    24481 actaaattct atgtctttat ttagtaaaaa aaacatcacc caaactaagg gattaaacca
    24541 atggacaaca agagctacaa gcataaataa ctttaacaga ttatcaaagc tattaatatg
    24601 aaccatttca tgagttaaaa caaagtctaa agtttgatta ttagcataat tcatttgctt
    24661 tggcaaaata attcgtggtt ttaaaatacc agatgtaagt ggtgtcctag taaattcaga
    24721 tatgcaaaca ataaatcttc taaaacggct attcttacac atccattttt taatgaactc
    24781 atgatttttt atatgaattg aagttttaaa aagattaatt attttaaaat atctaaagca
    24841 taaaagtatg ctaaacataa tagtaactat aaaagacaaa atgcccaaca tttccaacat
    24901 cataatattt tcaatactag acattatttc aaattcgtca gaattgtttt tacctgtaga
    24961 gtcactagct ttcttaagag tataattttc tgttgatgta ttacccaatt ccacatcaaa
    25021 agtcgattca attatactat aaatactaaa accagaattt aaacttactg gtattagaag
    25081 tttaaataaa acaatcaacc acaataatac aaataccttt ttaggtaatt ttttaaataa
    25141 acatgctctt ataaaaataa ctattaaaag taatactcca gaagtaaaac tcatttctaa
    25201 caatttaatg aacataaatc ttacctcact ttaatttttc aacaatttgt ttaagttttg
    25261 taatctcatc acttgaaaga ttttctttat taataaaagc tgaaagaaat ttttctgaag
    25321 accctccaaa cattttatta attaaagttt ctgtttcctg tttttgtact tcctctttgc
    25381 ttattaaagc tttacaaaca aaattcggct caattctctc tattgcacct tttgacacta
    25441 atttttttat aacggtatac gtagtgtttc tattccatcc tgtttcttct tttaaaattt
    25501 ttactaactc tccagccttg ctttctcctc tctcccatag aacttccatt actttaagtt
    25561 ctgaatcaaa taattttatc tccatataaa atcgctcctc aaatatagtt atcacaatag
    25621 tcattactat aataaaaaac tatcatagta gtctatacta tgtcaatcat ttatttttta
    25681 ataataaaaa ctgtcttttt aaaaaattct tataaaagac agttttatca atgttatact
    25741 ttaatgttta attaaagcca tattttattt aaatatataa ctatctatct tagtacatag
    25801 tataagattt ttctttatct aatagtatat cctctacatc tgggttttct tttactaatt
    25861 gtctataaaa attacaatta gtaacaccca catatggaat tagccatagt agacctattc
    25921 caagagtagc tattgaaagt atataccatc ctataaagct aaagtttagt acaaataatt
    25981 taagtacatt tcctttcatc atatctaaac tagcacccat tgatttaaat acacccatat
    26041 tatccttgtc ttcacaaatt aagaaagtag cttgagaaac atataatagc aatatataaa
    26101 ctggtaacat aagaacaagt attataagaa ctagagttat tccagtagaa ataatagtcc
    26161 ctattccaac attatcactt gataaatatt caattgctcc actagtaagt aaaactccaa
    26221 atgataaaaa cgctcctata attgtgatta taaaagaata aatatacaca ataattgatt
    26281 caaataaata aaaaccaaaa cttcttaaat aaattctccc acttacaaag atatctccta
    26341 tcttgacttt ttcatcttta gtaattttca agaacataca tgtaaatcct gctgaaacgc
    26401 aaaaagctat tacagccact acaatagtag tcaatggttc aaaaggtaat cctacaattg
    26461 atattaatac tatcaatgca atatatactg ccatagaaat tgcacatatc ccccagtttc
    26521 cagataactg agctttagat actcgtttta attcttgcct tgataccata aaaaacaccc
    26581 ctttcatttt ataaaaaaac ttttaaaaat ataaataatc ttttaacgta taatattaat
    26641 atatcatatt ttcgactata taagatacaa ttattcacca tgttttatca agatatgcca
    26701 taattgtatt actagtttta tatagtcaac attaccaaat acatcaaata aatttgatta
    26761 attattcaac aagtaataaa ataatttcta ttaattatac tttatttagt aaacaaatta
    26821 tttaataaaa aaattaccta atacagtaaa ttaattggta agataaatta
//
LOCUS       DAMJXI010000049        26754 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.051, whole genome shotgun sequence.
ACCESSION   DAMJXI010000049 DAMJXI010000000
VERSION     DAMJXI010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26754
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.051"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            549..1199
                     /locus_tag="PC465_002603"
     CDS             549..1199
                     /locus_tag="PC465_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDF2649889.1"
                     /translation="MDFISSILQGLLSILFNFTGDFGISIVLITLIVKLVLMPLSLKQ
                     RFSVKKQQELAEKMEHIKEKYKNDTKELEKQIQVSSVESMKSMLGCLIVLVQMPVVYA
                     LYHVCLDMTKEFTTIIIPWIANLGTFDNLFILPCIYTLIMLASNLVNYIPYLKINSQV
                     KFNKQMAVVTTITSLILTVRTPVAIGLYFITSAIYSLIEDICFRIYFNRKNRIVTK"
     gene            1413..2084
                     /locus_tag="PC465_002604"
     CDS             1413..2084
                     /locus_tag="PC465_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2649890.1"
                     /translation="MAKILIVEDEKRMQSIIVEYMQKGGYTCITADDGVEALTILKSN
                     NIDLMILDIMMPYLDGFSVCRVSREMTNIPIIILTAKGEEEDKLKGYEYGADDYITKP
                     FSPKVLLAKVNALLRRYTTDIPKNSLSLGKIFIMVASRQVYVEDKLIDLTYKEFELLR
                     LFMENPNQVFSREKLLNCIWGYDFEGNTRTVDTHIKTLRKKLGSEGHHIVTLIRSGYK
                     FEVKE"
     gene            2081..3211
                     /locus_tag="PC465_002605"
     CDS             2081..3211
                     /locus_tag="PC465_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2649891.1"
                     /translation="MNSLRKIIEKLKNVDISNWIKQNFGLYSVRKKVFLLSKLSGALI
                     ILFYLVVEEFSINSKFEFWIWFIILVIFIMSIDFLLGKFISEPITSINKSAKSMSQLD
                     FSNPCTVNTNDEFGELSRSLNTMSTNLQQALSDLESANIQLEKDVNKERMLLEQRKEL
                     VDTISHEMKTPLGIIRAYTEGLMDEVDEEKKKNYMNVIIEETDRMNNMIVSLLDLSAL
                     EAGVSKLNPERFDFIEFVETVAGRLLIDIPDANFYFTYDLPEYEVFVVADKIRMEQVV
                     ENLIINAKKHVVYNGNLDLSITCENGLLLFKIYNDGRIIEQDEISKIWSKFYRSVQSQ
                     RTGGSGLGLAIVSQILTMQGLEYGVNNRDRGVEFYFMIPIDE"
     gene            3626..4471
                     /locus_tag="PC465_002606"
     CDS             3626..4471
                     /locus_tag="PC465_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2649892.1"
                     /translation="MIKVEELKFSYGKDKQILHGLNFEVKEGEIFGFLGPNGSGKSTT
                     QKILNGVLKGYNGHVSIFGKEVKAYTESLYQKIGVLFEFPYLYTNLSAIDNLEYFSSF
                     YPKNQRRDIYELLDLLEFKKEFINKPVSSYSKGMKQRISMARALVSNPKLLFLDEPTS
                     GLDPSGAVLFRKIIEEERKKGTTIFLTTHNMLDADLMCNNVAFIADGKIMVIDKPKNL
                     KMKNSNNKVEVEFVYNGNRDIEIVDIQELESGITFKYDEILSVHSKEPTLEEVFIKYT
                     GRMLV"
     gene            4471..5499
                     /locus_tag="PC465_002607"
     CDS             4471..5499
                     /locus_tag="PC465_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2649893.1"
                     /translation="MYSKFFTLVKKEFWMMIYGKFFVLTLGSLILYSCYINFGYVKFM
                     DEDSYHNNVYLYNPENISMSASPLINQVSSIGELKAKLDEDTSAVCIDMSSSKPKVIL
                     HESIKGVDDYRADYALSLLSSEKDHNSKISDNNAIIQINDKDTSEIKQRKDMTCEILF
                     FEIVAIGFLGIASLLFKEKQMGVMRITGILPVKRSLFILSKIFAFLICDLCFTVLLVV
                     FNIGFFEGIKILPQVLVQASILSIIMSLIGIGCSMLLRDFKQFSLIYLVVAVFITTPI
                     FLSANTSFEIDWIKYHPFYHVYSQLKNAFFMNFSKELVYFVVCSLTIIVLFLLVKYIF
                     NKELVREG"
     gene            5502..6515
                     /locus_tag="PC465_002608"
     CDS             5502..6515
                     /locus_tag="PC465_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2649894.1"
                     /translation="MIGLRYQLKSIKKDKMCIISFFLPVVMAILINFMGTIDISSLGE
                     IRFGIVKDTLPVQTEQWLKKYGMVSVYDTKMHLIREIKDIKTDTIGVVRDGKGIKTVL
                     YGNEINAIKNVGKTLPEMFRLKGDLKDVEVTILPKDSILKEFQNVFIAMILITAMFMG
                     CTFNAMNIISEKEDGISFINEVLPQSRSQYIIQKVFLGLLCGCLSSMITVFICLDISI
                     LDMIMMLLLVVFSAFISSLIGLFIGKLSEGLMVGIVYIKIVMILFIGTPLLIYLLGVN
                     TSGIGNLCYIMPSVATFNGIMEIINGNVIIIKDIVILAVHCVVWFMIYIILDKKRKLS
                     FSR"
     gene            complement(7043..8293)
                     /gene="cme"
                     /locus_tag="PC465_002609"
     CDS             complement(7043..8293)
                     /gene="cme"
                     /locus_tag="PC465_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Cme"
                     /protein_id="HDF2649895.1"
                     /translation="MENKNTNSTWKKKVILFLASQYISLFGSSLVQMAMIWYVTLQTS
                     SGVWVTVLTVCSFIPQMIISFFAGVWADYYNRKVLIIVSDSTIAISTLVLILFMMSSN
                     GTTSELIAISVISVIRSLGSGVQTPAVNAMIPQLVPEEHLMRFNGINSSLQSIVQFIV
                     PIVAAAILGFGNKINQVLLIDVFTAIIAIVLLIFIKIPKHDIPKQTEKVSFFADMVSG
                     IKYCFSDKFIRKVLFTYGAFMLLCVPSGFLIGLLIERTFGKGYIYLSIIEMIGFLGMV
                     LGGLIIGVFGGFKNRNKTFFLAILSYAIFSIILGLVTQAWQFFIFMFFTNFSIPIIQA
                     SAMTMLQEHVAPQMLGRVLSLPIIIYTGFIPLGMMIFGPMADVISINNLIIIAGIILL
                     FFALAIPYSKQFYKQGISKSNESE"
     gene            complement(8379..9125)
                     /locus_tag="PC465_002610"
     CDS             complement(8379..9125)
                     /locus_tag="PC465_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2649896.1"
                     /translation="MDTYTTSEVADLIGVHPNTVRLYEELNLIPKPKRNTNGYRIFND
                     FHIEQFRFARTALKIEVVQRGLRKDALEIVRTSANRDFDKAISLVNQYLQQLEIEKSN
                     AEEALTIVAQILNGNTPETNKLFLTRKETAEHLNVTIDTLRNWEMNGLLKVKRKQNGY
                     RVYTDEDIKRLKIISALRCANYSLSAILRMLNALSSNPNTNIKTVLDTPKDDDEIISV
                     CDKLITSLKEAEHNAKTMKSHLQIMKKQFS"
     gene            complement(9354..10376)
                     /locus_tag="PC465_002611"
     CDS             complement(9354..10376)
                     /locus_tag="PC465_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HDF2649897.1"
                     /translation="MNKNNCLDLIFEKVDPSSVGMSSEKLSQLEPLIISQYSNINGII
                     IARKGKIVFEKYYNGYNADDTFHVASVTKSIISALIGIAIDKGYIKDVDQKVVDFFPE
                     YTCSPSEICKKAVTIRHLLTMTAPYPFKNMTESLERLCKQKDWIKYTLNQLGQKGEIG
                     TFKYSSAGTHLLSAIITKTTGKSAREFANEYLFKPIGMKVIPDYDMKDFGFEDFFGKN
                     LKGWAKDRQGYSIGGWGLTLSARDMLRFGFLYLNDGIWNNKRIISKSWIEESVKMNSN
                     EYGYLWWLCKKDGVLWYSAMGTGGNAICCIPQYDLVIAIPSKIVFKPRDRWEFIEKYI
                     LTSIID"
     gene            complement(10376..12796)
                     /locus_tag="PC465_002612"
     CDS             complement(10376..12796)
                     /locus_tag="PC465_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF2649898.1"
                     /translation="MKEIKINGAKIHNLKNIDVSIPKDKLVVATGVSGSGKSSLMFDI
                     VFEEGRKQYLQSLGILAGIDSEDKFDNIQGLAPTIAVQQNIIRQSNPRSTVGTRTNIL
                     NMLTLLYSVEGQIMCTMCDTPVSDNLICNNCGYEEERLRPSYFSYNSSDGMCMKCSGH
                     GAYFEINIEKLVLDKHDTLKQVLDRAKITPGYLRVFSKKFNDYLDIQFLQLPEEIRNE
                     VLYGHYENGKKSSSLSKVFHNRYKRGEDLNGVYTMTACSDCNGFKIGEEARRVLLNGK
                     HIGELGKMTILEIDDFLKLLINQGNLNTFGTNLVNDILSKTQHLIESRLGHLSLYREM
                     STLSGGEMQRLFLNSHLDSEMDSLIYVLDEPTAGLHESEKIDILKSIKKLKDLGNTVI
                     VVEHDKNTIKMAEHIIDIGPKAGVEGGQLVYQGDLEGLLQSNKSLTGQYLSGKYPMPN
                     RTSNKNITHTDKIPCITIQNANTNNLKNVTVSLPLSAMVGISGKSGSGKSSLISDTLL
                     PLLRSQFNNHTINNQINSSESEIGEEDDYAVVETIADRLIGTKHISGYSEISQSPIGK
                     NMNSTPASYIGIWDKIRTLFAGQPKSLERGFTAGHFSFNSKGACPKCSGSGYEKVWLG
                     NNLSIDHICSECQGKRFNDESLSIKYKNKNIHDILNMSVSESVYFFKDIPNIVSHLNV
                     LEQIGMGYIKLGQPTPTLSGGESQRIKLAKEIGKKRNGNILYVLDEPTTGLSLYDTSK
                     LIQLLDELVENGNSVIVVEHDIDVLNVCDWIVELGPEGGDKGGYIIAEGSPKALKENP
                     KSITGRYL"
     gene            complement(12882..13802)
                     /locus_tag="PC465_002613"
     CDS             complement(12882..13802)
                     /locus_tag="PC465_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2649899.1"
                     /translation="MTNAKSKKEYLNRICKVQDYIEEHLHEPLSLDELSNIAGFSKFH
                     FHRIFKAIEKETLAQYVNRLKLENATAFLIHRTDMTVTDIAHYFGFTDSAVFSRAFKN
                     YYKISPIKYRNNYSKNCKEPYKISQYNRSISKPKCKNTREVKGEIEILELDNMNTIYT
                     RYTGSYGNLTSTFPKLLERLFTYASEQNLLGLENTQILAIYHDNPQFTQEHQLRTSIC
                     MTIPDNIVVKENDNLGNMIIPSGKYLVGHFDISKSEYSDAWDFMYNEWLSNGNYKLRA
                     SFPFEVYLNNPHNHPQNRHLVDIYLPIEPF"
     gene            14392..15318
                     /locus_tag="PC465_002614"
     CDS             14392..15318
                     /locus_tag="PC465_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HDF2649900.1"
                     /translation="MSNSFYQLNSAVLYFNEKRDVNRIRFNHYVMRKENIQRLKGTLP
                     RGQFMMTVRKAASDLDVSISTISRLVNEFIDLGILRLISRGVKGNCCSVYSYVCSESS
                     NAEIVTKNGDIFKNIEKYIDATINNNQKTMKYKHRDELFKNSNTNIYSRINQESIDKD
                     YDLIIHTGYETENETKKKELLKNNLNKKNLNKNTFENSDEDLTEDSTYKNPESIHEII
                     IRKLNSESGKNFKADLSITKALIDKRLKEGYSLEDFYKVIEAKVRRWRYTDMEIYIEP
                     TILFGYEFESYLNEESSLSACNYGDMCYEDMY"
     gene            complement(15678..17330)
                     /locus_tag="PC465_002615"
     CDS             complement(15678..17330)
                     /locus_tag="PC465_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp21"
                     /protein_id="HDF2649901.1"
                     /translation="MNKKNLAILISGMMFFSSSSAIFADNTTKQERLIGKTRYETAVE
                     VSKLGWVQSKTAIIVNGNSIQSALCANPFAKLKNAPILLVNNNSIENSTKAELKRLGV
                     DNVYIVDSGNSISSKVENEIKSLNIKINKIVGNNIYEMSTNVLKEIDKIKKVENVAVV
                     NGLKGLSDAVSIASPAAIHNMPIILVSDENSNDSSINFLNNRSIKKSYIVGGNKILSD
                     NTVKKYPNRERISGSDRNNTNAKIIDKFYKDKKINNVFVAKDGINQENALVDSLSIGV
                     LAAKENSPIMISNGSLVNSQKEFIKNKDIDEITQVGGGYNQKAFEDILKLKNVNIRNK
                     TKKISLIQAKEILKQALPGSNILVCYYDEDDNEYDCKVIKDNILYEIEIDAYSGKIIE
                     IEKDDDLNDNNLGTQNISLDKAKSIALDAIPNGNLIYCKYDAEDNEYEAKVIKNKKTY
                     ELEISAFDGRIVDIDMDNDSDDDFDDNDKNNSNTNDNSSIISAEKAKSIMLDKVPGGK
                     IVKFKYDEDDKEYEGEIIKGKTEYEITINAITGKILEFEIDD"
     gene            17929..19050
                     /locus_tag="PC465_002616"
     CDS             17929..19050
                     /locus_tag="PC465_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDF2649902.1"
                     /translation="MEAKKLGFGLMRLPIKDENDVTTIDMEHLNKMVDTFLERGFTYF
                     DTAYVYHMGKSEIALRESLVKRHKRESFTIATKLPLMALKKKEEQETIFNEQLEKCGV
                     DYFDYYLLHNIGVSHYEVAKKFDSFKFIEEKKKEGKIKNIGFSFHDSAELLDKVLSEH
                     PEVDFVQLQINYLDWDNESIQSRKCYEVAEKHNKPVIVMEPVKGGTLAKIPEKAEKLL
                     NDYNPDMSISSWAIRFAASKDNVMMVLSGMSNMEQLLDNTGYMQNFKPFVQEEYNIID
                     EAVEIINESILVPCTACQYCVEGCPKNIAIPNYFALYNAEKQALNTGFSTQMVYYNNY
                     TKTYGKASDCIECKQCEESCPQHIKIIDALKNVAETFEK"
     gene            19086..19499
                     /locus_tag="PC465_002617"
     CDS             19086..19499
                     /locus_tag="PC465_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2649903.1"
                     /translation="MTISEVSKKYELSADTLRYYERIGLIPPVNRNKSGIRSFTEEDC
                     EWVNFIKCMRGAGLSIETLIEYVAMFQQGSSTIKARKELLIEQRNQLAKRIEEMQKTL
                     ERLNFKIDRYEEGIIEKEKVLKSSRNKKMEAVSYE"
     gene            19492..20031
                     /locus_tag="PC465_002618"
     CDS             19492..20031
                     /locus_tag="PC465_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2649904.1"
                     /translation="MSKNVLIVSASPRKGGNSDLLCDQFIQGVLESKNQVEKIFLKDK
                     DINYCTGCGACYEKEANCSQTDDMGEILEKMIEADVIVLATPVYFYTMNAQMKTMIDR
                     TCSRYTEICDKDFYFIVTAADENVADMERTIEGFRGFTSCLNGSKEKGIVYGVGAWNV
                     GDIKGSKAMKQAYEMGKLA"
     gene            complement(20231..20716)
                     /locus_tag="PC465_002619"
     CDS             complement(20231..20716)
                     /locus_tag="PC465_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649905.1"
                     /translation="MSKSELTAETTEEMLEVLSGKDYDIACHLHELGKSLDCKIEPKT
                     GARSYKIVYSTKKPKRSLFTIECNEKKWRVKANLFHLNTYKDAVEECSKTIKDSITKT
                     RTCKKCNSKCIGGSSFELDGKSYLTCIGSGHYFANMEEMDWKNLEKLITKENNIMQES
                     V"
     gene            21621..21998
                     /locus_tag="PC465_002620"
     CDS             21621..21998
                     /locus_tag="PC465_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDF2649906.1"
                     /translation="MSKVVIATEKAPGAIGPYSQAIQVGNIVSTSGQLPIDMKTGELV
                     SDPKEATKASLDNVKAILEQAGTSMDKIFKTTVFVKDLKDFNDINEVYATYFKENPPA
                     RSCVQVAQLPKDAVLEIEAMAVL"
     gene            22394..24199
                     /locus_tag="PC465_002621"
     CDS             22394..24199
                     /locus_tag="PC465_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2649907.1"
                     /translation="MLSKLKEFQQEMIKYTETVASVLDVDIEIVDDRLIRISGTGLYK
                     SKINESVVTEGFIYDNVIQTGQELVVLDICDNQLCIECSHYMKCLNKVIIAVPIKYNN
                     RTIGVIGAISTDKTKKVEISAKIDNYLKFVNHICDLISMKIEEHEASKNSSRKMDMMI
                     EIIENVEKGVIILDINSKISYINNIALKKLDIDKNIIENIVNIVSVESSSNGHELLEI
                     DIDNKIYNINAKIIPVYPYINQYDKIIIFDKTYINHKGHGKVNSGWGNSDIESIIGNS
                     EAMLKVKERTKKLAKSNSTVLITGESGTGKELIARAIHAEGSRWNKPFIAINCAAIPE
                     NLLESELFGYIKGAFSGASSGGKVGKFELANEGVIFLDEIGDLSMPLQAKLLRVLQER
                     KFARIGSNKLIDLDIRVIAATNKNLLKLVNEGKFRDDLYYRLNVIPINLPPLRERKDD
                     IEAIMMKFASKYSLELGIQLNKIEENVMNMLINYNWPGNIRELENAVEYMMNLVGDDG
                     IIYKDMLPLDILNYYNINGNIYKNKDVNIIFEDDIVGGIVENQERILSIKELELTYIN
                     KLLNKYGRDTKTKKKIAKDLGIGLATLYRKLEEEQ"
     gene            24276..24815
                     /locus_tag="PC465_002622"
     CDS             24276..24815
                     /locus_tag="PC465_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2'-5' RNA ligase family protein"
                     /protein_id="HDF2649908.1"
                     /translation="MQYAIELYYDKKTEKQLFDLSKKIADEKISTKYLEWKTRPHLTL
                     ACFNDVDEACCIDKLKGFAQNHKVIPAYIGSVGMFNDTKTVFVSPIMNSSMYQFQREL
                     YEVLQDFDSNGWEWYHPNRWVPHCTIALTGDDESEAFFRASDVLLREFKKISGEFVSI
                     GLVKITFPVEEIFTVNMNR"
     gene            25429..26643
                     /gene="dpaL"
                     /locus_tag="PC465_002623"
     CDS             25429..26643
                     /gene="dpaL"
                     /locus_tag="PC465_002623"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HDF2649909.1"
                     /translation="MREIKWKLNNLPKSEEKEKGIEFLKDEEIAKAKAFHESFPQYEK
                     TPLVKLDNLAKLLGVSGIYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLNTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAKEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNYSSAFVSAPDWVSAKGMRILGNP
                     LRGDEKVISGESGAVTTGALVSILESEDLKDLREALKLDENSKVLLISTEGDTDPDKY
                     RDIVWNGECQSK"
BASE COUNT         9878 a         3232 c         4302 g         9342 t
ORIGIN      
        1 ataagctata aaaacttaat attgttttgt tcagagataa aaaaagaata ctttaggtga
       61 tttttattaa aaattaagag tgataaaatt atatacttta taaatgtaaa tatgacgaat
      121 aaaaatgata aatataataa tatatatatt tacattagga gttttctata ctataattat
      181 ttaaaactaa atataaatgt tggaattatt taggacttga aattgtctaa aaataaatat
      241 aagtgatgaa gaggtgatgt gatgagatta gatatggata gtatgttata tgtactaatt
      301 tatatgacat tattggtatc tatcattgga agtatatttt atttttgtaa agacctctta
      361 aatcataaaa ttaagtatgt tttaataaga gacatatttg taaatagaat tacatattct
      421 gaagaacggt tgcctaaaca gtatatagtt tttcagaaat atgatatttg gaggtattgt
      481 agtttgtttt aatttgaaat gaatctatta taaattctaa agtttaaaaa taaaaaggag
      541 agaataaaat ggatttcatt tcaagtatat tgcaaggatt attaagtata ttatttaatt
      601 ttacaggtga ttttggaatt tctattgtac ttataacttt aatagttaaa ttagtactta
      661 tgccactatc attaaaacaa agattttctg taaaaaaaca gcaagaatta gctgaaaaaa
      721 tggaacatat aaaagaaaag tataagaatg atactaaaga attggaaaag caaatacaag
      781 taagttctgt agaaagtatg aagagtatgc tgggatgtct tatagttttg gttcaaatgc
      841 cagtagtata tgctttatat catgtatgtt tagatatgac aaaggaattt acaacaatta
      901 taattccatg gattgctaat ttaggtacat ttgataattt gtttatatta ccttgtatat
      961 atacattaat tatgttagct tcaaatttag tgaattatat accatattta aaaataaatt
     1021 ctcaagtaaa gtttaacaaa caaatggctg tggtgactac cataacaagt cttatactaa
     1081 ctgttagaac tccagtagcc ataggtctgt actttataac aagtgcaatt tattcattaa
     1141 ttgaagatat ttgttttaga atatatttta atcgaaaaaa tagaatagtg acaaaataat
     1201 ataattatta ttagaaatat tttagcctgc taacatagaa aaagttagta ggctattttt
     1261 atctatgata tcaattccat taagaatagt ctaaaaaata ctatcaaaat gctataaaaa
     1321 atactatcaa aatactataa aaaaatagtt gaaaaataaa taaattaata taaactaaaa
     1381 taaagcctac aaaaaagagg tgataaatag aaatggctaa aatactaatt gtagaagatg
     1441 aaaaaaggat gcaaagtatt attgtagaat atatgcaaaa gggaggatat acttgtataa
     1501 ctgctgatga tggagtcgag gcacttacaa tattaaagag caacaatata gatttaatga
     1561 tattggatat tatgatgccg tatttagatg gattttcagt gtgtagagtt tcacgtgaaa
     1621 tgactaatat acctattatt atattgacag ctaaaggtga agaggaggac aaattaaagg
     1681 gttatgaata tggcgcagat gattatataa caaaaccatt tagccccaaa gtacttttag
     1741 caaaagttaa tgccttgtta cgtagataca ctactgatat tcccaaaaat tcattgagtt
     1801 taggaaagat ttttattatg gtagcatcaa ggcaagtgta tgtagaagat aaattgattg
     1861 atttaacata taaagaattt gaattattgc gtttatttat ggaaaaccct aatcaagttt
     1921 tttccagaga gaaactttta aattgtatat ggggatatga ttttgaagga aacacacgaa
     1981 ctgtagatac acatataaaa accttacgca aaaagcttgg tagtgaagga caccatatag
     2041 ttacattaat tcgttcagga tataagtttg aggttaagga atgaatagtt taagaaagat
     2101 tatagaaaaa ctgaaaaatg tagatatttc aaattggatt aaacaaaatt ttggactata
     2161 ttcagttaga aaaaaagtgt ttttactttc taaattatca ggagcgttaa ttatattatt
     2221 ttatctggtt gttgaagaat tttcgataaa ctctaaattt gaattttgga tttggtttat
     2281 aatactggtt atatttatta tgagtattga tttcttattg ggaaaattta tttcagaacc
     2341 aatcacatct ataaataaat ctgcaaaaag tatgtcccaa cttgattttt ctaatccatg
     2401 tactgtaaat actaatgatg aatttggaga actttctagg agcctgaata caatgtctac
     2461 aaatctacaa caggcattat cagacctaga aagtgcaaat attcaacttg aaaaggatgt
     2521 aaataaggaa agaatgctat tggaacaaag aaaggagttg gtagatacaa tttcacatga
     2581 aatgaagact ccacttggca ttatacgtgc gtatacagag gggcttatgg atgaagttga
     2641 tgaagaaaaa aagaaaaatt atatgaatgt tataatagaa gaaactgata gaatgaacaa
     2701 tatgattgta tcattattag acttatctgc attggaagca ggagtttcta aacttaaccc
     2761 agagcgtttt gattttatag agtttgttga aactgtggca ggtcgtcttt taattgatat
     2821 accagatgcc aatttttatt ttacatatga tttgccagag tatgaagttt ttgtagtggc
     2881 agataaaata agaatggaac aagtagtaga gaatctaatt attaatgcaa agaagcatgt
     2941 tgtatataat ggtaatttag atttatcgat tacatgtgaa aatggcttgc ttttatttaa
     3001 aatttataat gatggtagga ttatagagca agatgagatt tcaaagattt ggtctaagtt
     3061 ttatcgtagt gttcaatctc agcgtacagg aggttcaggt ctagggcttg caattgtttc
     3121 acaaatactt acaatgcaag ggttagaata tggagtgaat aatcgtgata gaggagtaga
     3181 gttttatttt atgattccaa ttgatgaata atttagtatt aatttataaa ttataagtat
     3241 ctgatgtaaa atatttttct ttgtagacaa tagatatcta aagagaataa aataaaaaag
     3301 tctaataaaa aaatttaata aaaagcttaa tgagaagtct tgttttcctg atgaaaacaa
     3361 gattttttat taagcttttt attatttcac ttcgatttca caagagagac actttgattt
     3421 caccaaatag aaataaaata agttaaataa attaaaaaaa tataagaagt aattaaatac
     3481 gcttacaagg gggggcactt atgaaatggt atacatggtt gactattata ttgataatat
     3541 tggtttctat tccgcttaaa attaaattta taaaatggtg ggatagacga caaaaagaaa
     3601 aaaataatga aggaggctat gatagatgat aaaagtagaa gagttgaaat tttcttatgg
     3661 aaaagataaa cagatattgc atggacttaa ttttgaagta aaagaaggag aaatatttgg
     3721 atttcttgga cctaatggtt caggaaaatc cacaacacaa aaaatcttaa atggtgtttt
     3781 aaaaggttac aatggtcatg tatccatttt tggtaaggaa gttaaagcat acacagaatc
     3841 tttatatcaa aagattggtg ttttatttga atttccttat ttatatacca atttaagtgc
     3901 aattgataat ttagaatatt tttcgtcttt ttatcctaaa aatcaaagga gagatatata
     3961 tgaactctta gatttgttag agtttaagaa agagtttata aataagcctg tatcatccta
     4021 ctcaaaaggt atgaagcaac gtattagtat ggcaagagca ttggtaagta atccaaagtt
     4081 gttattttta gatgagccta ctagtggact tgacccatct ggagctgtac tatttcgtaa
     4141 gattattgaa gaagaacgaa aaaaaggaac aactatcttt ttgactactc ataatatgct
     4201 agatgcagat ttaatgtgta acaatgtggc ttttattgca gatggaaaga ttatggtaat
     4261 agataaaccc aaaaatttaa aaatgaaaaa tagcaataat aaagttgaag tggaatttgt
     4321 atataatgga aatcgagata ttgaaattgt agatatacaa gagttagaat ctggaataac
     4381 ttttaaatat gatgaaatct taagtgtaca ttcaaaagaa cctacactag aagaagtttt
     4441 tattaaatac acaggaagga tgttagtgta atgtactcta aattttttac cttagtaaaa
     4501 aaagagtttt ggatgatgat ttatggtaaa ttttttgtgc tgacacttgg ctctctcata
     4561 ctttattcgt gttatattaa ttttggttat gtaaagttta tggatgaaga tagttatcac
     4621 aataatgtat atctatataa tccagagaat ataagcatga gtgcatctcc attaattaat
     4681 caagtttctt ctataggtga attaaaagca aaacttgatg aagatacaag tgcagtttgt
     4741 attgatatga gttccagtaa gccgaaagta attttacatg aaagtattaa aggagttgac
     4801 gattatagag ctgactatgc attgtcatta ttatcatcag aaaaagacca taatagcaaa
     4861 atatcagaca acaatgcaat aattcaaatt aatgataagg atacatctga gataaaacaa
     4921 agaaaagaca tgacttgtga gattttattc tttgaaattg tagctattgg atttttaggg
     4981 attgcctctt tattatttaa agaaaagcag atgggagtaa tgcgtattac tggtatttta
     5041 cctgtaaaaa gaagtctttt tatattatca aagatatttg cttttttgat atgtgaccta
     5101 tgttttacag ttcttttagt agtatttaat attggatttt ttgaaggaat aaaaatactt
     5161 ccacaagtat tagttcaagc tagtatttta tcaattatta tgtctttgat tggaatagga
     5221 tgctcaatgt tattgagaga ttttaagcaa ttttctctta tatatcttgt ggttgctgta
     5281 ttcataacta cacctatatt tctatctgca aatacatctt ttgaaataga ttggattaaa
     5341 tatcatccct tctatcatgt ttatagtcag cttaaaaatg cgtttttcat gaatttttca
     5401 aaagaattag tttattttgt agtgtgttct ttgacaataa tagttctatt tttacttgta
     5461 aaatatattt ttaataaaga gttggttagg gagggataat cttgatagga ttacgttacc
     5521 agttaaagag tataaaaaaa gataaaatgt gtataatttc cttcttttta ccagttgtta
     5581 tggcgatttt aataaatttt atgggaacaa ttgatatatc ttcattaggg gagatacgtt
     5641 ttggtatagt gaaggataca cttcctgtac aaacagagca gtggttgaag aagtatggta
     5701 tggtaagtgt atatgacaca aaaatgcatt taatacgtga aattaaggat attaaaacgg
     5761 acacaattgg agttgttaga gatggtaaag ggataaaaac tgtgctttat ggaaatgaga
     5821 ttaatgctat aaaaaatgtt ggaaagacat tgccagagat gtttagacta aagggtgatt
     5881 taaaagatgt tgaggttaca atattgccta aagatagtat tttaaaagag tttcaaaatg
     5941 tttttattgc catgatttta attactgcta tgtttatggg atgcaccttt aatgcaatga
     6001 atattatatc tgaaaaagaa gatggaatat catttataaa tgaagttttg ccacagagta
     6061 gaagtcagta tattatacaa aaagtatttt tgggtctttt atgtgggtgt ttatcttcaa
     6121 tgataactgt atttatatgt ttggatattt caatattaga tatgataatg atgttgttac
     6181 tcgttgtatt ttcagcattt atttcatcac ttataggttt atttattgga aagttgtcag
     6241 aaggtcttat ggtaggaatt gtttatatta aaatagtaat gattttattt ataggtactc
     6301 ctttgttaat atatcttcta ggggttaata ccagtggtat agggaattta tgctatataa
     6361 tgccttcagt tgctacattt aatggtatta tggagattat taatggtaat gtcattatta
     6421 tcaaagatat tgtaattttg gctgtacatt gtgtagtatg gtttatgata tatattattt
     6481 tagataaaaa aagaaagtta tcttttagta gataactcag tataattata attgggacaa
     6541 tttaataggt gatttaatat actttgtata gtgtaattta tgtagtgcaa tttgtatact
     6601 ttaatttatg tagtgtaata gttagtttta ttttataatt attcaatata atttagtaag
     6661 aagttcagta caattagagc tacttagtgg aaaacttaat aggtacttaa actatataaa
     6721 tactttattt tcctccattt gtactataaa tttaatttat gatataaatg gaggtattat
     6781 tatatgattt gataaatttc atcattataa cctacaagta aaggtattat tatataaagt
     6841 taataaagat agtatcaaaa tattatttgc tataaagaga gggactcaaa ataaagataa
     6901 acctattttt caatgttgaa atgataaaat atatttaatt tcatataaaa aattttcttc
     6961 ataaattaaa aagtccattt taagcccccc tcagcccccc tcatttttaa ccagataaat
     7021 cgagttaaac tatttaaata tattactcgg attcatttga cttagatatt ccttgcttgt
     7081 aaaattgttt tgaatagggg atagccaaag caaaaaataa aagtataatc cctgctatga
     7141 ttattaaatt attaatagaa attacatctg ccattggtcc gaaaatcatc ataccaagag
     7201 gaataaaacc agtatatata ataataggta agctaagaac tcgacctagc atttgtggtg
     7261 ctacatgctc ttgcaacata gtcatagctg atgcttgaat aattggaatt gaaaaattcg
     7321 taaaaaacat aaatataaaa aattgccaag cttgtgttac aagacctaga ataattgaaa
     7381 aaatagcata ggataatatt gctagaaaaa aggtcttatt tctattttta aaaccaccaa
     7441 aaactcctat aatcaatcca cctaaaacca tacctaaaaa tccaatcatt tcaataatag
     7501 acaggtatat ataacccttg ccaaatgttc gttcaataag aagtcctata agaaatcctg
     7561 atggaacaca aagaagcatg aatgctccat aagtaaaaag cacttttcta atgaacttat
     7621 ctgaaaaaca gtactttatc cctgatacca tatctgcaaa aaatgagact ttttcagttt
     7681 gttttggtat atcatgttta ggaattttga tgaatatcaa taatacaata gcaataattg
     7741 cagtaaatac atcaattaaa agaacttgat ttattttatt accaaatcca agtattgcag
     7801 cagctacaat aggaactata aattgtacta tagattgtag gctactattt ataccattaa
     7861 aacgcattaa atgttcttct ggtacaagtt gaggaatcat tgcgtttaca gcaggtgttt
     7921 gtacaccact tcctagtgaa cgtataacag atattactga tatggctatt aattcacttg
     7981 ttgtgccatt tgatgacatc ataaatagaa ttagaactaa tgtagatata gcaattgttg
     8041 aatctgatac aattatgagt acctttcgat tgtagtagtc tgcccataca ccagcaaaaa
     8101 aagaaattat catttgaggt ataaaggagc atacagttaa aactgttacc catacacctg
     8161 atgatgtctg aagtgtgaca taccatatca ttgccatttg tacaagtgat gagccaaata
     8221 aggaaatata ttgacttgct aaaaaaagaa tgactttttt cttccatgta gaattagtat
     8281 ttttgttttc catcctattc ctcctttgat ttgtgtgttg aatttttctt gctcttaagg
     8341 ataacacaca aatcaaagtc tggagttaga gtggagggct aggaaaattg ttttttcata
     8401 atttgaagat gagatttcat ggtttttgca ttatgttcag cttctttcaa tgaagttatc
     8461 agtttgtcac acactgagat aatttcgtca tcatcttttg gagtgtcaag gacagtttta
     8521 atattagtat taggattaga agataaagca tttaacattc gtaaaatagc tgaaagagaa
     8581 taatttgcac aacgaagtgc gcttataatt ttaagtcgtt ttatatcttc atcagtatat
     8641 acacgataac cattttgttt tctttttact tttaacaaac cattcatttc ccaatttctt
     8701 aaagtatcta ttgtaacatt taagtgttct gcagtttctt ttctagttaa aaagagttta
     8761 tttgtttctg gagtatttcc atttaaaatc tgtgcaacaa tagtaagtgc ttcctcggca
     8821 ttagattttt ctatttctaa ttgttgcaag tattgattta caagactaat agccttatca
     8881 aagtccctat tcgctgatgt tcttacaatc tcaagggcat cttttcttaa tcccctttgt
     8941 accacttcaa ttttcaaggc tgtacgagca aatctaaatt gttctatatg aaaatcatta
     9001 aagatacgat aaccattggt attacgctta ggtttaggta ttaagtttag ttcttcatat
     9061 aaacgtactg tattaggatg tacaccaatt aaatctgcta cctctgatgt cgtgtaagtg
     9121 tccattagta ttcaactcct tttagatata tagtattagt cataataaca ccaaacaaaa
     9181 gtctggtgtt ataatggagg gtttggctat ctaagagtaa ttagtttatg aaagagtaat
     9241 tagtttatga aagagtaatt agtttatgaa agagtaatta gtttatgaaa gagtaattag
     9301 tttatgaaag agtaattagt ttatgaaaga gtaattaatc tatgaaagag taattaatct
     9361 attatagaag taagtatata tttttcaata aactcccatc tatcacgagg tttaaacact
     9421 attttagatg gtatggctat tactaagtca tattgtggaa tacaacaaat agcatttcct
     9481 ccagttccca ttgctgaata ccacaaaaca ccatcttttt tacatagcca ccacagataa
     9541 ccgtattcat tactattcat tttaactgat tcttcaatcc acgatttaga tataatacgt
     9601 ttattattcc aaataccatc atttaaatac agaaaaccaa atcgcaacat atctctagca
     9661 ctcaatgtaa gtccccagcc acctatagaa taaccctgtc tatcttttgc ccaaccctta
     9721 agattttttc caaagaaatc ttcaaaacca aaatctttca tatcataatc tggtataact
     9781 ttcataccaa taggtttaaa taagtattca ttagcaaatt cacgagcaga ttttccagta
     9841 gtttttgtta taatagctga aagtaggtgc gttccagctg aagaatattt gaaagtacca
     9901 atttcgcctt tttgaccaag ttgattcaag gtatatttta tccaatcttt ttgtttgcaa
     9961 agtctttcta aagactcagt catattttta aaagggtatg gtgcagtcat tgtaagtagg
    10021 tgacgtatag ttactgcttt tttacatatt tcagaaggac tacaagtata ttcaggaaaa
    10081 aaatcaacaa ccttttggtc aacatctttt atatatcctt tatctattgc aatacctatt
    10141 aaggctgata taatactttt tgtaactgat gcaacatgaa aagtatcatc agcattatat
    10201 ccattatagt acttttcaaa gacaattttt ccttttcttg caataattat accatttata
    10261 ttgctatatt gtgagattat taaaggttca agttgtgaaa gcttttctga actcatacca
    10321 acacttgaag gatctacttt ttcaaaaatt aagtctaagc aattgttttt attcattaaa
    10381 gatacctccc tgttatagat tttggatttt cttttagagc ttttggagaa ccttctgcaa
    10441 ttatataacc tcctttgtca ccaccttctg gaccaagctc aacaatccag tcacaaacat
    10501 ttaatacatc tatatcatgt tcaacaacaa ttacagaatt tccattttca accaattcat
    10561 ctaataattg aatcaactta gaagtatcat atagacttag accagtagtt ggctcatcca
    10621 atacataaag gatattacca tttcgttttt taccaatttc ttttgcaagt ttgattcttt
    10681 gggattcacc accacttaaa gttggtgtag gttggcctaa ttttatatac cccataccta
    10741 tttgttctaa tacatttaag tgtgaaacaa tatttggaat atccttgaag aaatatacag
    10801 attcagaaac actcatattt aaaatatcat gtatattttt atttttatat ttaatagata
    10861 aagattcatc attaaatctt tttccctgac attcactgca tatatggtct atacttagat
    10921 tatttcccaa ccagaccttt tcatatccac taccactaca tttaggacaa gcacctttgg
    10981 agttaaatga gaaatgacca gctgtaaatc ctcgttctaa cgattttggc tgacctgcaa
    11041 atagtgtacg tatcttatcc catataccaa tataagaagc aggagttgag ttcatatttt
    11101 tgccaatagg agattgggat atctctgaat atccagaaat atgtttagta ccaatcagtc
    11161 tatctgcaat agtttcaaca actgcataat cgtcttcctc acctatttca ctctctgaag
    11221 aatttatttg attattgata gtatggttat taaattggct tctaagaaga ggaagtaggg
    11281 tgtctgatat aagtgaactc ttgccactac ctgattttcc agatattcca accatagcac
    11341 tcaaaggtaa tgatacagtt acatttttaa gattatttgt atttgcattt tgaatagtta
    11401 tacaaggtat tttatcagta tgtgtaatat ttttattgct tgttctatta ggcattggat
    11461 attttccaga tagatactgc ccagtaagtg atttgttgga ttgaagtaga ccttctaaat
    11521 ctccttgata tactaattga ccaccttcaa caccagcttt tggaccaata tcaataatat
    11581 gttctgccat tttaattgtg tttttatcat gctcaactac tatgaccgta ttgcctaaat
    11641 ctttaagttt ctttattgat tttaagatgt ctattttttc tgattcatgc aatccagctg
    11701 ttggttcatc aagcacataa attaatgagt ccatctctga atcgagatgt gaatttaaaa
    11761 atagtctttg catttcccca ccactcaaag ttgacatttc tcggtataag gatagatgac
    11821 ctaatcgtga ttctattaaa tgttgagttt tggataaaat atcatttaca agatttgtac
    11881 caaatgtgtt taaattacct tgatttatta agagtttaag gaaatcatca atttctaaaa
    11941 tcgtcatttt tccaagttct ccaatatgtt ttccgtttaa aagtactcta cgtgcttctt
    12001 caccaatttt aaaaccatta caatctgaac aggcagtcat agtataaact ccatttaaat
    12061 cttcgcccct tttgtaacga ttgtgaaata cctttgataa agaggaactt tttttaccat
    12121 tttcataatg accatagagt acttcatttc ttatttcttc aggtagttgt aagaattgta
    12181 tgtctaaata atcgttgaat tttttagaaa atactctcaa atatcctggt gtaatctttg
    12241 ctctatctaa gacttgtttt agggtgtcat gcttatcaag gactaatttt tcaatattaa
    12301 tctcaaaata tgcaccatgt ccagagcact tcatacacat tccatctgaa gagttgtatg
    12361 agaaataact tggtcttaat cgttcttcct catatccaca attattgcaa attagattat
    12421 cgcttacagg agtatcacac atagtacaca ttatttgacc ttccactgaa tacaatagtg
    12481 taagcatgtt gagaatattg gttcttgtgc ctactgttga acgaggattg ctctggcgaa
    12541 taatattttg ttgaacagct atagtgggag ctaaaccttg aatattatca aacttatctt
    12601 cactatcaat acctgcaagt atacctaaag attgcagata ttgtttacgc ccttcctcaa
    12661 atacaatgtc aaacataagg ctagacttac ctgagccact gacacctgtt gcaacaacaa
    12721 gcttatcttt ggggatagaa acatctatat ttttaagatt gtgtatcttt gctccattaa
    12781 tttttatttc tttcattggt tcacctcatt ttatcaattt tatcaaaccg taaaataggg
    12841 atatattaat ccttaataca agaatagatt aggtgaggtt attaaaaagg ttctataggt
    12901 aaatatatat cgaccaagtg tctattttga gggtgattgt gtgggttgtt aagatatact
    12961 tcaaaaggga aggaggcacg tagcttataa ttaccatttg atagccattc attatacata
    13021 aaatcccacg catcactata ttcagatttt gaaatatcaa aatgtcccac aagatatttt
    13081 ccagaaggta ttatcatatt gccaagattg tcattctctt tgacaactat gttatctgga
    13141 atagtcatgc aaatactagt ccttaattga tgctcctgtg taaattgtgg attatcatga
    13201 taaatggcta atatttgtgt gttttcaagt ccaagtagat tctgctcact tgcatatgtg
    13261 aataaccgtt ctaaaagttt tgggaaagta ctggttagat taccatatga accagtatac
    13321 ctagtgtaaa tagtattcat attatcaagt tctagaattt caatttcacc tttaacctct
    13381 ctagtattct tacatttagg ttttgatatg cttctattgt actgagaaat tttatatggt
    13441 tctttgcaat tcttgctata attgtttcta tattttatag ggcttatttt atagtaattt
    13501 ttaaatgctc tcgagaaaac tgctgaatca gtaaagccaa agtagtgtgc aatatcagta
    13561 acagtcatgt cagttctatg aataagaaaa gcagttgcat tttctagttt tagcctattt
    13621 acatactgtg ccaaagtttc tttttctatt gctttgaaga ttctatgaaa atgaaatttt
    13681 gaaaaacctg ctatattaga aagttcatca agagaaagag gttcatgtaa atgttcttct
    13741 atatagtctt gcactttgca aatacgattt agatattctt ttttactttt agcatttgtc
    13801 atatatagcc ctccttattg tgtaaaatgt gtatcaatta atttatagca atatagtaat
    13861 aaaattttat gtttttgtaa tttatgataa ataagatagc gtttaatttt ttataattga
    13921 taaaagatat aagatgcctt atatttgtct ttgcatataa gtatagtctt cgtaataatt
    13981 agtataccat agtgatttat ttttaattgt gtatttatat aaatacacaa cttatgatat
    14041 ggacgaatta ttatgcaaat aagctgtaat taaataaatt gcaatataaa ccagttgaaa
    14101 cataagttag ggaaatatta tcaaagttat tatttagcat aagagtatag agggaataaa
    14161 ataagattaa aaaattacat actaaattta ataaaatttt tatattaaaa ataatattaa
    14221 gtttattgtt taaataaaaa agttaaatct acactattaa cttattatac ttaaaacttt
    14281 aaaatgaaaa tatcaaagaa tactttttaa taaaaataat catttaataa gttatttaaa
    14341 aatctaaaaa ctttacaaca aattatctat ttaaattgga ggagtgggaa tatgagtaat
    14401 agtttttatc aattaaattc agcagtatta tattttaatg aaaaaagaga tgtaaataga
    14461 ataaggttta atcactatgt aatgagaaaa gaaaatatac aaagattaaa aggaactctg
    14521 ccaagaggac aatttatgat gacagtaagg aaagctgcat ctgaccttga tgtatctata
    14581 tctacaataa gtagacttgt aaatgaattt atagatttag gtatattgag gttaataagt
    14641 aggggagtaa agggaaattg ttgttctgta tatagttatg tttgttctga aagtagtaat
    14701 gcagaaattg taacaaagaa tggtgatatt ttcaaaaata tagagaaata cattgatgca
    14761 actattaaca ataaccaaaa aacaatgaaa tataaacata gagatgagtt gtttaagaac
    14821 agtaatacca acatatacag ccgtataaat caagagagta tagacaaaga ttatgatttg
    14881 ataattcata ctgggtatga aacagaaaat gagacaaaga aaaaagaatt attaaaaaat
    14941 aatttaaata aaaagaattt aaataaaaat acctttgaaa attcggatga agatttgact
    15001 gaagattcta cttataaaaa tccagaaagc atacatgaaa ttattataag aaaattaaat
    15061 agtgaatcag gaaaaaattt taaagctgat ttgagtataa ctaaggcact tatagataaa
    15121 agattaaaag aagggtatag tttagaagat ttttacaagg ttatagaggc aaaggtaaga
    15181 agatggagat atacagatat ggaaatatat atagaaccaa caattctgtt tgggtatgaa
    15241 tttgagtcgt atttaaatga ggagagttct ttatctgctt gtaattatgg tgatatgtgt
    15301 tatgaagata tgtattgaga tatttattaa gatattagtt gctttttagt tgtttaaaat
    15361 atgtttatgt ataaatagtg tattaaaatg gagttgtctc aaaatagaga gaagcctctt
    15421 cttaattgtt taaatgatga aaatatattt gatttaatac aaaggagagt gctttatgag
    15481 ttagaagatt tattttgaga cactcacttt ttttaatata ctggagaaat ataacccatt
    15541 ttacaagagt gcataggtat atataatggc ataatgtgga tttaaattaa aaaaaataaa
    15601 ataaagccat aaatattgaa attttcaata tttatggctt tattgcttgt aataattaat
    15661 agaatatata ttttttatta atcatctatt tcaaattcta atattttacc agtaattgca
    15721 ttaattgtta tctcatattc agtttttcct tttattattt caccttcata ttctttgtca
    15781 tcttcatcat acttaaattt tactattttc ccaccaggca ctttatctag cattattgat
    15841 ttagcttttt cagcactaat aatagaactg ttgtcattag tattagagtt attcttatca
    15901 ttatcatcaa agtcatcatc agaatcattg tccatgtcaa tatctacaat tcttccatca
    15961 aatgcactta tctctaattc atatgttttc ttatttttta ttactttagc ctcatattcg
    16021 ttatcttcag catcatattt acaatagatt aaattaccat taggaatagc atctaatgct
    16081 atagacttag ctttatccaa tgatatattt tgtgtaccta aattattatc atttaagtca
    16141 tcatcttttt caatttctat tattttacca gagtaggcat caatttctat ctcatatagg
    16201 atattatcct ttataacttt gcagtcatat tcattatcat cttcatcata ataacaaact
    16261 aaaatattgc ttcctggaag agcttgtttt aatatttctt tagcctgtat taaagatatt
    16321 tttttagttt tatttcttat gttcacattt tttagtttta aaatatcttc aaatgctttt
    16381 tgattatatc ctcctcctac ttgtgttatt tcatctatat ctttattttt aataaattct
    16441 ttttgactat ttacaaggct accattagat atcattatag gagaattttc tttagcagct
    16501 agtactccta ttgataatga atctactaat gcattttctt ggttaatacc atctttagct
    16561 acaaatacat tatttatttt tttatcttta taaaatttat caataatttt tgcattagta
    16621 ttgtttctat ctgaaccact gattctttct ctgtttggat atttctttac tgtattgtct
    16681 gataaaatct tatttcctcc aactatgtaa gattttttta tagacctatt gtttaagaaa
    16741 tttatactac tatcattgct gttttcatct gatactaata ttataggcat attatgtatt
    16801 gctgctggag aagctatact aactgcatca gatagtccct ttagtccatt tacaactgca
    16861 acattttcta ccttttttat cttatctatt tctttaagta catttgtaga catttcatat
    16921 atattgtttc ctactatttt atttattttt atgttaagtg attttatttc attttctact
    16981 ttggaagaaa tgctatttcc actatctaca atgtacacat tatctacacc aagcctttta
    17041 agctcagcct tagttgaatt ttcaatactg ttgttgttta ctaaaagtat aggtgcattc
    17101 tttagcttag caaatggatt tgcacaaagt gcactttgaa tagaattacc attaactata
    17161 atggctgttt ttgattgaac ccatcccaat ttacttactt ctactgctgt ttcatatctt
    17221 gttttaccta ttaatctttc ttgctttgta gtattgtctg caaaaattgc tgaagaacta
    17281 gaaaaaaaca tcatacctga tattaatata gctaaatttt tcttattcat atttttacct
    17341 cacaatcttt aaaaatttgt tatttagcat acttaataaa atataatctt aaaatcaaat
    17401 tgatgctgag tttgaagtta caaaatcaac aaataagatt tctttaatac aaaattttcc
    17461 tttttatatt taacattgta tcacaaatat aaaaaggaaa aaacttttta aaaagggtat
    17521 acactattca ttttttatct tataaataag tctttaccac tgttttatat attttaaaat
    17581 agacacaaga cctatttcta aatcttttat aaacatttta ggtgaaattt ctttttaaac
    17641 atatctaaaa agtatttgta gtaatattaa tggactgaat ttcttaaagt atatatttct
    17701 ttacatgttg gagtttgtga agtttgagaa ttggagggtg aaagaaacat gtaatggatt
    17761 aatattaaag aactgtattt ttataatatt tgtcttaaaa ataaaaaaat ctattgactt
    17821 gaagttaact ccaagtagta aagtataatt atacaagaat tatatacttg taagaatagt
    17881 taaagtagag agaaaaaaca aacaagtttt aaagggggaa gtaaaacaat ggaggcaaaa
    17941 aaattaggat ttggattaat gcgtttacca ataaaagatg aaaatgatgt tacaactatt
    18001 gatatggaac atttaaataa aatggtagac acttttttag aaaggggatt tacatatttt
    18061 gatacagcct atgtgtatca catgggaaaa agtgagatag cacttagaga atctctagta
    18121 aaaagacaca aaagagagag ttttactata gctacaaaac ttccattaat ggctttaaag
    18181 aaaaaagaag agcaagaaac catttttaat gagcaattag aaaaatgtgg tgtagactat
    18241 tttgactact atcttttaca caatataggc gtgtcacatt atgaagtagc taaaaaattt
    18301 gatagcttta agtttattga agaaaagaaa aaagaaggaa aaataaagaa tattggtttt
    18361 tcttttcatg atagtgcaga attattggat aaagtcttga gtgagcatcc agaagtagac
    18421 ttcgtgcaat tacagattaa ttatttagat tgggataatg aaagcataca atctagaaaa
    18481 tgctacgagg tggcagagaa gcataataag cctgtaattg ttatggagcc agtaaaagga
    18541 ggtacacttg caaagatacc agaaaaagca gagaaattat tgaatgacta caatccagat
    18601 atgtcaattt catcttgggc aatacgtttt gcagcaagta aagataatgt tatgatggtc
    18661 ttaagtggga tgtcaaatat ggaacaatta ttagacaata caggatatat gcaaaatttc
    18721 aaaccattcg tacaagagga atataatatt atagatgaag cagtagagat tatcaacgaa
    18781 tcaattttag ttccttgtac tgcctgtcag tattgtgtag aaggctgtcc aaaaaatatc
    18841 gctattccaa actattttgc gttgtacaat gcagaaaaac aagctcttaa tactggattt
    18901 tcaacacaga tggtctacta taataattat actaaaactt atggaaaggc ctcagattgt
    18961 attgaatgta aacaatgtga agaaagctgt cctcaacaca ttaaaattat agatgcttta
    19021 aagaatgtag cagaaacctt tgagaaataa ttcaatctat acaatatcaa gaggagaaga
    19081 tatgtatgac gatttcagaa gttagtaaaa aatacgagct ttcagcggat actttacgat
    19141 attatgaacg aattggttta ataccacctg taaatagaaa taaaagtgga attaggtctt
    19201 ttacagaaga agattgtgag tgggttaatt tcataaagtg tatgagaggt gcaggtcttt
    19261 ctattgagac attaattgag tatgtagcta tgtttcaaca agggagcagt actatcaaag
    19321 ctagaaaaga acttttaata gagcagagaa accaactagc aaaaagaata gaagaaatgc
    19381 aaaaaacttt ggaacgatta aattttaaga ttgatagata tgaagaaggt attattgaga
    19441 aagaaaaagt attaaagagc agtagaaata agaaaatgga ggcagtatct tatgagtaaa
    19501 aatgtattaa tagtatcagc tagtcctaga aaaggtggaa attctgattt attgtgtgac
    19561 cagtttatac aaggggtatt agaatctaaa aatcaagtgg agaagatatt tttaaaagat
    19621 aaagatatta actattgtac tggatgtggt gcttgttatg aaaaagaagc aaattgttca
    19681 cagacagatg acatgggaga aattcttgaa aaaatgattg aggcagatgt gattgtttta
    19741 gcgactccag tttattttta tactatgaat gcgcaaatga aaactatgat tgatagaact
    19801 tgctctagat atactgaaat ttgtgataaa gatttctatt ttatcgttac agcagcagat
    19861 gaaaatgtgg ctgatatgga aagaacaata gaaggattta gaggatttac atcatgtcta
    19921 aatggttcta aggaaaaagg tatagtatat ggtgtaggtg cttggaatgt aggtgatatt
    19981 aagggaagta aggcaatgaa acaggcatat gaaatgggta agttggcgta gtatgtttgt
    20041 ataaaattgt ataaaattga atatattctt atcatttcaa caataaaaag aggcttatct
    20101 gtattttgag acagcctctt tgtgctatat catttatttt tattctatat ccttattata
    20161 ccctttattt ttttatgcct atttaagtat ctgttgttac tcatatattt taataattac
    20221 ccttaaaaaa ctatacagat tcctgcataa tattattttc tttagtaatt aatttttcta
    20281 ggtttttcca atccatttct tccatatttg caaaataatg accacttcct atgcaagtca
    20341 ggtaagactt tccatctaat tcaaacgaag aacctccaat acactttgaa ttacatttct
    20401 tacaagtacg agttttagtt atactatctt taatagtttt agagcattcc tccacagcat
    20461 ctttatatgt atttagatga aaaagatttg ctttaactct ccattttttt tcattacatt
    20521 caatagtaaa taagctacgt tttggtttct tagttgaata tactattttg taagaacgag
    20581 cacctgtttt tggttcaatt ttacaatcta atgatttacc aagttcatgt aaatgacatg
    20641 caatatcata atctttacca cttagtactt ctaacatttc ttctgttgtt tctgctgtta
    20701 attcactttt gctcatatta aaaaaatccc cctatataaa taataatttc atatgaaaat
    20761 aattaatata agtatattaa ataaaactat taaaatcaat aaaattactg caatcttaca
    20821 ttattgggca tagaatgaga gctaatgatt tattagaaat aagacttaat agtatgaaaa
    20881 tttacttaga cgtggtacaa ttctataaaa gatttaaaac taggaaagga gaaagttgtt
    20941 gagatacggc caatataaca atttatttat aagttgtaaa tttattatga gattaattag
    21001 attgttaagt aatactatca aaaggtagtt ttttggattt tcagcaacag tggtagatat
    21061 tgataatttt ttggttatta ttatatttag ctgttatatt ttcaataggc tctatgataa
    21121 ctagggtaaa taaggtatgg gtaaaggttt tattatttat aatagtggga ttgtcaacta
    21181 tagttctttc atatgtaata acttgattat gcaaaattct atgaagcagg aaccctgtga
    21241 ctttagtcat gggaggttca gaatttaagg ttaaaaaata actttaatct gtaaattctc
    21301 aaaacaagaa ttctcatgtt ggtaaatttc tagatatgag aaaaaaattg acatcataaa
    21361 aaagtaattt tagagcgttt tttgacgaaa aaattcagaa gtaactattt tgaatgactt
    21421 cacaaaattt tatatataaa taaagtttgg cacgttaatt gctttaataa aagttaacaa
    21481 gacacaaata aacataatca tctaagtatt gattatttga agttttagat ttgaaattta
    21541 atctaaaggt tcgtattaat attggtgttt aggaaatttt attttcctgt aaatataact
    21601 taataatagg aggtgaagtc atgtcaaaag tagtaatagc tacagagaaa gctccaggag
    21661 caattggacc atattctcaa gcaattcaag ttggaaacat agtttctaca tcaggtcaac
    21721 ttccaataga tatgaagact ggcgagttag tatctgaccc aaaagaagca acaaaagctt
    21781 ctttagataa tgtaaaagca atattagaac aagctggtac aagtatggat aaaatattta
    21841 agactacagt attcgtaaaa gatttaaagg attttaatga tattaatgaa gtatatgcta
    21901 catattttaa agaaaatcca ccagcaaggt catgcgtaca agttgctcaa ttaccaaaag
    21961 atgcagtttt agaaattgaa gcaatggcag tattataagt attataacaa taaaaccaat
    22021 aacaaaacta ataaaaatta aaaactaata aaaaaagtct acaattaaaa aagtttatat
    22081 taaaaaagtc tatataaaaa tctatctaaa tatttaacta ttgagctttt ctcatataat
    22141 gtatattttt atgtcaaaaa tatatttgtt atatgaggaa agcttttttt tattattgta
    22201 ttgtgattta ttttattgtc tgcatattat aattaaggtt actatataaa acaaactttt
    22261 tataaattaa tattgtctgt tttaacgcaa atatataaat aagtaatgtt ttatatatat
    22321 tttaaagagt gactatatgt taaaatatag ctaaactgat aatttggtaa attaaattct
    22381 aatgggggaa actatgttaa gtaaattaaa agaatttcaa caagaaatga taaaatacac
    22441 tgaaacagta gctagtgtgt tagatgtaga tattgaaata gttgacgata gattaataag
    22501 aattagtggt acaggtctgt ataaatcaaa gataaatgaa agcgttgtta cagaaggatt
    22561 tatttatgac aatgttatac agacaggtca ggaattagtc gtattggata tatgtgataa
    22621 tcagctttgt atagaatgtt cccattacat gaaatgctta aataaagtaa taatagcagt
    22681 tccaataaag tataataatc gaactatagg agtaattggt gctattagta cagataaaac
    22741 taaaaaagta gaaataagtg caaaaataga taattattta aaatttgtta atcatatatg
    22801 cgatttaatt tctatgaaaa tagaagaaca tgaagcgtca aaaaatagca gtagaaaaat
    22861 ggatatgatg atagaaatca ttgaaaatgt tgaaaaaggc gttataatac tagacataaa
    22921 tagcaaaata tcttatataa acaatatagc tctaaaaaaa ttagatatag ataaaaatat
    22981 aatagaaaat atagtaaata tagtatctgt tgaatcttcc tcaaatggac atgaattact
    23041 agaaattgat attgataaca aaatttataa tataaatgcc aaaataattc cggtatatcc
    23101 atatataaat caatacgaca aaataataat atttgacaag acatatatca atcataaagg
    23161 acatggaaaa gtgaatagtg gctggggaaa tagtgatata gagtctataa ttggaaattc
    23221 agaagcaatg ttaaaagtaa aagagagaac taagaaatta gcaaagtcaa attcaactgt
    23281 acttataact ggggaaagtg gtacgggtaa agagctaatt gctagggcta tacatgctga
    23341 aggtagcaga tggaacaagc catttattgc gataaactgt gctgctattc cagaaaatct
    23401 ccttgaaagt gagctatttg gctatataaa aggtgcattt agtggagcta gtagtggagg
    23461 gaaagtaggt aaatttgaac ttgcaaatga aggtgttata tttcttgatg aaataggaga
    23521 tttgtcaatg cctttacaag caaagttact tagagtttta caagagagaa aatttgcgag
    23581 aattgggtca aataaactta tagatttaga tataagagtg attgctgcta caaataaaaa
    23641 cttattgaaa ttagtaaatg aaggtaagtt tagggatgat ttatactata gattgaatgt
    23701 aattcctata aatttgccac ctcttaggga aagaaaggat gatattgagg caataatgat
    23761 gaagtttgct tctaaatatt ctttagaatt aggtattcag ttaaataaaa tagaagaaaa
    23821 tgtaatgaat atgttgatta actataattg gccgggaaat ataagggaac tggaaaatgc
    23881 agttgaatat atgatgaatt tggttggaga tgatggaata atatataaag atatgcttcc
    23941 attagatatt ttaaactatt ataatattaa tggaaatatt tataaaaata aggatgtaaa
    24001 tataatattt gaagatgata tagttggagg gatagtagag aatcaagaaa ggatactttc
    24061 aattaaagaa ttagagttga cttacataaa caagttgttg aataagtatg gaagagatac
    24121 aaagacgaag aagaagatag caaaagactt aggcataggt ttggctacac tatatagaaa
    24181 attggaagag gaacagtagt aatataatat taaaatgata ggtatttgtg tgtttttata
    24241 gataggtatt tttactttat ggtggaggtg ttattatgca atatgcgata gagctatatt
    24301 atgataaaaa aacggaaaag caactttttg atttatctaa aaaaatcgct gatgaaaaaa
    24361 ttagtacgaa gtacttagaa tggaaaacaa gacctcatct tactttggct tgtttcaatg
    24421 atgtggatga ggcttgttgc atagacaagc taaaggggtt tgcacaaaac cataaggtaa
    24481 tacctgctta cattggttca gtaggcatgt ttaatgatac taaaacggtg tttgtatcac
    24541 ctataatgaa tagcagtatg tatcagtttc agagagaatt atatgaggta ctacaagatt
    24601 ttgattcaaa tggttgggaa tggtaccacc ccaatcgttg ggtaccccat tgcacaatag
    24661 cacttactgg agatgatgaa agtgaggctt tttttcgggc aagtgatgta ttactgcgtg
    24721 agttcaaaaa aataagtggt gagtttgtct caataggatt ggttaaaatt acatttcctg
    24781 tggaagaaat ttttacagtg aatatgaata ggtaacttta actctgttgt ggatgttatg
    24841 aatattttgt atagtgcatt tcatcagata aatgcgaagt tgcgaatttc gacagctcaa
    24901 tagtcgcaag tagggcacaa tggtacacat attgcacttt tgcttattgg ggggacgccc
    24961 atgtaaactt ctgtaagaag ctatgaaaag atttaagcca ttttggaggc tttgggtaat
    25021 aaagaatata aagtatataa agtatataaa tttatagagt ttatgcgtaa gaaggttata
    25081 gccatatatt tatagaaaat aaaagtagta atatatctga caaaacaata gacatataaa
    25141 aaataagagc ataataaagg aagaattaag acaaataaac gatttctcga attgataatt
    25201 ctcgtattga taaaaatttc ccaatatgag aattttttct tttataaatc ttatttttca
    25261 cactcaaaat ttataaactt taaagaaatt ttataaaagt atgtaattcc aacataaaaa
    25321 aattgttttt agaataaata atattggcac ggtaattgct ttgctataag gcacaaagat
    25381 aaaaaattaa aatgacaccg aaaaatttga aaggggaata taaaataaat gagagaaata
    25441 aaatggaaat taaataactt acctaaatca gaggaaaaag aaaaaggaat tgaattttta
    25501 aaagatgaag agattgcaaa ggctaaagct tttcatgaga gctttccaca atatgaaaag
    25561 actcctttag ttaaattaga taacttagca aaattactag gcgtaagcgg aatatatgtt
    25621 aaagatgaat cttatagatt tggcttaaac gcatttaaag ttttaggtgg ttcttactct
    25681 atgggtagat acttagctca aagattaaat acagatatat ctgagttagg gtatgataaa
    25741 ttaacttcaa aagaaataaa agaaaaatta ggagaaataa ctttctttac agctacagat
    25801 ggaaatcatg gtagaggagt tgcttggaca gctaataaat taggtcaaaa atctgttgta
    25861 ttaatgccaa aaggttcttc tgaatttaga ttaaataaaa tcaaaggaga aggtgcagat
    25921 gctagtataa cagacttaaa ctatgatgat gcagtaagat tagctaatga ttatgcagaa
    25981 gctgatgacc atggagtaat ggttcaagat acagcatggg acggatatga agaaatacca
    26041 gcatggataa tgcaaggata tggaactatg gctaaagaag ctatagaaca attaaaagaa
    26101 tatggagtag atagaccaac acacgtattt gttcaagcag gagttggttc acttgctggt
    26161 gcagttcaag gatatgttgc ttcaatatat gatgaatgcc caataacagt agtagtagag
    26221 gctgatgagg ctgattgtta ctataaatca gcagaagctg gagatggaaa accaagattt
    26281 gttggaggag atatgccaac tataatggca gggcttgctt gtggagaacc aaacactata
    26341 ggttttgaag tgttaaaaaa ttattcatca gcattcgttt cagcaccaga ctgggtatct
    26401 gctaaaggta tgagaatatt aggaaaccct ctaagaggag atgagaaagt aatctctgga
    26461 gaatctggag cagttacaac tggagcatta gtttcaatcc ttgaaagtga agatttaaaa
    26521 gacttaagag aagctttgaa actagatgag aactctaaag tattattaat aagtacagaa
    26581 ggagatactg accctgataa atatagagat atagtttgga atggtgaatg ccaaagtaaa
    26641 taaaagactt aaggaaaaga aaaacttaac aaataaatga aaaatttaag gaaaataaaa
    26701 acttaaataa gtgaaaactt taaataaaat aaaaactaaa acaaatgaaa aatc
//
LOCUS       DAMJXI010000050        25643 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.052, whole genome shotgun sequence.
ACCESSION   DAMJXI010000050 DAMJXI010000000
VERSION     DAMJXI010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25643
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.052"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(442..2829)
                     /gene="cadA"
                     /locus_tag="PC465_002624"
     CDS             complement(442..2829)
                     /gene="cadA"
                     /locus_tag="PC465_002624"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HDF2649910.1"
                     /translation="MEANNLIKKEFILGGLNCAHCAEEINNKVSKLQEVKSSNLNFIN
                     KKLTVNIKESFNEDTTIEKIIDIIDSTEPGLDIQISSKENASSKISIKKELILGGLNC
                     AHCAEEINNKVSKLKEVESSNLNFVNKKLTVNISNNFEADDVINKIKEIINSTEPGLD
                     IQVESTNKVKGRTTEKPGAVNDTNKKELIPLIIGALVYIFGIYQTATGYESQFSNIVF
                     IVAYVIVGGDVLLRAIRNISKGRVFDENFLMALATVGALAIGELSEAVGVMLFYKVGE
                     YLQGVAVGKSRKSITSLMQIRPDYANLKVNSEVKVVSPEEVNVGDIIVVKPGEKVPLD
                     GVVVDGISMLDTSALTGESVLREVEKGDEILSGVINKNALLSIEVTKSFGESTVSKIL
                     DLVENSSIKKSKTENFISKFSRYYTPIVVIAALLIAFVPPLVISGEVFSDWLYRGLIF
                     LVVSCPCALVLSIPLSFFSGIGFASKNGILIKGSNYLEALRSVDTVVFDKTGTLTKGV
                     FNVTKLNPEGISEEELLEYAAIAEVNSNHPIAKSILSYYNKKIDLDTIDSYEEIAAYG
                     IRVKHNGNFILAGNEKLMKKENISYSSAKEVGTVVYIAVDKVYRGYIVISDEVKEDSK
                     NAIRSLKAIGVKEVVMLTGDNEKVAKNIAQELELDTVYSNLLPNEKVDRLEDLYEGRT
                     EKEKIAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVLMTDEPSKISKAIEIA
                     NKTNKIVWQNIIFALGVKIIVMILGAGGVATMWEAIFADVGVALIAVVNAMRAMR"
     gene            complement(2852..3217)
                     /locus_tag="PC465_002625"
     CDS             complement(2852..3217)
                     /locus_tag="PC465_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2649911.1"
                     /translation="MREEINDCNCNIVHEEIVTEAKSTMPDEEMLYDLAELFKVFGDT
                     TRVKILYALFANEMCVCDIASLLNMTHSAISHQLRVLKQARLVKFRREGKTVYYSLDD
                     SHISQIFDCGLNHIRETYK"
     gene            3417..4250
                     /locus_tag="PC465_002626"
     CDS             3417..4250
                     /locus_tag="PC465_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649912.1"
                     /translation="MSNKKKKDLDTSYMPYLDPANYADYITNEEIPQDELRNDPQISN
                     GYTKIPNNQNINNLYPNNVNHYPKSSNSPNNLPNTNNTSGNMNYNTSATNNMPNNMNN
                     NTGMPNNMSNNMNSNMGMPNNMPNNMNSNMGMPNNMPNNMNSNMGMPNNMNSNMGIPN
                     NMSNNMNSNMGMPNNMSGNMNNMYGNTSMPNNMNSNMGYNMNNTMSIPNFSCNQNMPP
                     NVLMMIPGVICHNTMQGMPVVMPSTMPPNIYPTPYGSSNMSIQGIPQTTNIEEFDEEE
                     M"
     gene            complement(4398..5486)
                     /locus_tag="PC465_002627"
     CDS             complement(4398..5486)
                     /locus_tag="PC465_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649913.1"
                     /translation="MNFNFAKATNSRLMGSLGLIINWIDDENNHFCQYFLLDAEGLGL
                     ADYVSLNNPTQEEAYMEEERLMGGFGSDRVELTKDESLFLVSYFGNKNLYYDKLLPGD
                     KCEYIDIIKNYKTDLTIEKLYNKICKRVDEEVEFINYMTMRFIAWDRESLKYFSGSDE
                     IANMHITNINGTLLKNVVSDKGQGRYISEALYEDNDGYYICKIAFCISKCYETGFRIN
                     SLLVTDKEPMYDFEVFDEISKSEFVSVYSVNSPEEFARVFYRENPFLLKSNMNEGIFF
                     TRFNFNNDHVKENVYIINNDMKAIYYLMGNKFFIGTYNENDCNYINEISQSNYSDYIK
                     FEEKFFFEQNALYDFAESGSLDFDDFLE"
     gene            5611..6339
                     /locus_tag="PC465_002628"
     CDS             5611..6339
                     /locus_tag="PC465_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HDF2649914.1"
                     /translation="MKNIAAFFDIDGTLYRDSLMVEHFKKLIKYDIIDQKNWYKHARD
                     TFMDWDKRQGNYDDYLLEICDLYVDSLKGLDKTCINFTSDQVIKLKADRVYKYTRSRI
                     EWHLNQGHIVIFISGSPGFLVEKMAKKYNVTDFLGSDYVFENNIFTGTVIPMWDSISK
                     NNAINDFVVKYDLDLSNSYAYGDTNGDINMLKRVGNPIAINPTKELLSQISLDEEISK
                     NVEIIVERKDIIYSLSTDVNIVDI"
     gene            complement(6540..7031)
                     /locus_tag="PC465_002629"
     CDS             complement(6540..7031)
                     /locus_tag="PC465_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649915.1"
                     /translation="MSIKVAYGGVLLALNVILLTLTNIIPVNTLFIMGLASLLVSIVI
                     MEWGFKSGIAFYIGSIVLGFIVMASKSQWIVYSLTFGIYGIVKYLIEKDRSIYIEYFM
                     KLVFANIMILILYFLLRTIVYIPINIFIIGSFEIAFIVYDYVYSSFIGYYNNRLRKML
                     FKK"
     gene            complement(7042..7485)
                     /locus_tag="PC465_002630"
     CDS             complement(7042..7485)
                     /locus_tag="PC465_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649916.1"
                     /translation="MYSNTYNNENFMRARSFIENSEFKKAYDFLKTLTDKCAEWYYLT
                     GFSAMNIGYYEEGEDFLKRAKFMEPENSEYSDALRSYTQYRNDYSNRADNYNRRRRND
                     LDGCCCCCCDDCCCCLGDDCCENCAKLWCLDSCCECFGGDLITCC"
     gene            complement(7475..8314)
                     /locus_tag="PC465_002631"
     CDS             complement(7475..8314)
                     /locus_tag="PC465_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649917.1"
                     /translation="MFGYVKINKMDLTFREYDYYKAYYCGLCKYLKRNHGEISRFSLN
                     YDITFLIVLLTAVYNPESISTEEVCIVNPFKKKKVITNDITEYAASMNILLTYYKLED
                     NLMDDKRIKDKLAYYIYKNKLKLAYEKYPEKAEYIKQQLNELNKLEKDKNINIDEVSS
                     IFGNIMGEVFVYKKDENERNLRMIGFNIGKYIYLLDAYEDLDEDFKKGRYNPFIEYID
                     KNDELKEKVKKIIVTSLGFLARGIDNLNLNKNVGIIENIIYSGVYLRYINILESRGGK
                     NVQ"
     gene            9084..9530
                     /locus_tag="PC465_002632"
     CDS             9084..9530
                     /locus_tag="PC465_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002599264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2649918.1"
                     /translation="MIKFEKLNIINNKDMKEILDTWESSVRATHDFLSEEKIISIKPQ
                     VKEGAKYVSNFLCVRDKKGLIKAFMGIHDFKIEMLFVGNYSIGNGIGKRLAEYAIEVL
                     NVNYVDVNEQNQQALGFYKHMGFKVFKKSEFDEQGNPFPILHMKLK"
     gene            complement(9760..9900)
                     /locus_tag="PC465_002633"
     CDS             complement(9760..9900)
                     /locus_tag="PC465_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649919.1"
                     /translation="MKNENISYLALGLCFGVILGSLFKNLAIGLSFGLVIGVVLDSKK
                     NK"
     gene            complement(10461..11846)
                     /locus_tag="PC465_002634"
     CDS             complement(10461..11846)
                     /locus_tag="PC465_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2649920.1"
                     /translation="MDNLNKKFLMEYIDEIQGELRDISDKIWKNPELQYKEYYASNLQ
                     KECLKKHGFSIEGLEGMDTAFVASYGEGRPVIAVLGEYDALDGLSQKVSTTKEPIVDG
                     GAGHGCGHNLLGTGSIGAVIAVKELIKLKKLKGTIKYYGCPAEEDLSGKVLMIKKGFF
                     DGIDCAFSWHPFDINTPIRIPTLANYSVKFRYNGISAHAAQAPYNGRSALDAVELMNI
                     GCNYLREHIFDNCRVHYVTTNGGKMPNIVPDFAEVWYYIRGVKMEHVRDVFGRIVDIA
                     KGAALMTGTIMEYDIISGVYDYIPNTILTDILSQNMKLVGVQNYNEDDYYFADKLAET
                     VSIDKRSSVSSVLSGNKDITKMNLHDEVTDDTFTHNNCISLSLDIGDVSYIIPTAQCS
                     CSVWPIGISAHTWQSCASAGSDMGFKAMLLASKSISCSINDVMLDELVINKAKKELKY
                     TVGSFEYTPII"
     gene            complement(12019..12762)
                     /locus_tag="PC465_002635"
     CDS             complement(12019..12762)
                     /locus_tag="PC465_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HDF2649921.1"
                     /translation="MKKVLIVGESWVKNITHIKGFDTFVTTHYEEAVKWLKEAIESGG
                     YETVHMPAHVAADSFPYKLEELNEYDCIILSDIGSNTFLLSNSTFIDCNSNPDRLELI
                     KEYVNNGGALIMVGGYMSFTGIDAKARFGETAIKDVLPITMIDKDDRVEKPAGIIPEV
                     IDSEHPVLKGIPTEWPKFLGYNKTVARDNCPVLATIGGDPFVAVGEFGKGKSAIFSSD
                     CAPHWGPKEFTDWKYYNKLWVNMLDWLTC"
     gene            complement(12782..14044)
                     /locus_tag="PC465_002636"
     CDS             complement(12782..14044)
                     /locus_tag="PC465_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2649922.1"
                     /translation="MKKILLDTLNSKKQEYIDYLKELVSIKTEDVGHGILGGFEKEGQ
                     EYIEKLANYIGFSVDRQEISEELIKKAKNIYKEGNLGHNYQDRYNLICKYSDDLPGKT
                     IVFNGHVDTMPPGDISKWKYNPYRATEDNGKLYGLGTADMKSGLIASILAVKLIKDSG
                     LNVPGNVKIMSVVDEEGGGNGTINAVMNGIGGDCCIICEPSEQNLIVAHMGFVFFEVE
                     VKGVSLHCGSKWEGVNAIEKAMLLLQDIKGLEHNWLMIYKHPLLPSPTINLGVINGGT
                     AGSTVPDKCVFNLCVHFLPNIMSYEQVVNDVTNVIMTRANGDLWLKDNKPNINIYQSG
                     LGFEMDKDSDFVVNAHKILEETLGKKLEIKGSTAGNDARVMKNLAEIPTLILGPGSIE
                     QCHSIDEYVEIKEYLDSILMYASLILNL"
     gene            complement(14228..15226)
                     /locus_tag="PC465_002637"
     CDS             complement(14228..15226)
                     /locus_tag="PC465_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HDF2649923.1"
                     /translation="MSSITKHKEEKSSPLLTKLTSVFRDQGSAAVGLVIIFIIMSVAS
                     SNFLTLDNLINVGRQISINAILAVGMTFVIITGGIDLSVGAVIALVGTFWATTVVNYN
                     APIWGGMILALAIGTILGVIKGAIISTQKLPPFIVTLAMLTIISGASFVFTGGRPISV
                     NTDAFKMLGRGYIGPIPIPVIIMIIVVIAGHFLLKRTNFGRHVHAVGGNEEAARLCGV
                     KVNKVIVKVYALAGLLTALAGIILSSRLASGSPTVGDGAELDAIAAVVLGGTNMMGGS
                     GSIVGTCIGVGIIGILGNGLNLLSVSSYNQMIIKGLVMLFAIWINNIKLKKSAKSK"
     gene            complement(15210..16721)
                     /locus_tag="PC465_002638"
     CDS             complement(15210..16721)
                     /locus_tag="PC465_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDF2649924.1"
                     /translation="MSNIILKLSNIAKEFPGVRALDNVNFELFHGEVHALLGENGAGK
                     STMIKILTGAHSKTSGKFIFEGKEIENISPDISKKIGINAIYQELTVFDELTVAQNIF
                     MGKEINGKVLTNDKKMNEEAKKIFDNMGIDINPNSLVKELSIAQKQMVEIARVLSSET
                     KVLIMDEPTSSISKKETEILFRLINDLKESGVSIIYISHRMEELFEICDRITIMRDGK
                     TISTLNTKDVSSEEELVNLMIDRKLDQFFPKRKVEIKEEIMRVESLTKNNVFNDISFN
                     IRKGEILGIGGLVGSKRSEIVEAIFGLRTYDSGKIYLNNEEVKFKTPSDAIENGLGLI
                     TEDRKGTGLFLQMSVKENTTMAGLKKISKFKSIIDRKKEKDILEKYIEALKIKTPHMN
                     QVIQSLSGGNQQKAIIARWLLLQPDILIMDEPTRGIDVNAKAEIYNLMGDLVESGVSI
                     IMISSEIPELISMSDRIMVMREGHISGFLEGEEMVENNVLKLAFGGKINEFNN"
     gene            complement(16775..17737)
                     /locus_tag="PC465_002639"
     CDS             complement(16775..17737)
                     /locus_tag="PC465_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDF2649925.1"
                     /translation="MRVRKILSLGIAGILAIGMLTGCSMEGPSKSDNKGGSDKKDLTI
                     GVSTITLQHQFFIDIDEGIKEKAKELGVKVIVNDPDQDVAKQTSAIEDFIQQNVDGMI
                     VLGTDNSAIVPAVEGAFEKMPVVTVDAVLNTENITSYVGTVSYDAGKKLGEYTKKYID
                     EKLGGKSEIAIVTDLKSQIQMQRIDGFKDALKGSANVKILNSQPGYDREESLNTVENL
                     IQSNPDVDIIYATAENSVLGAKAALESAKNKDVKIVGFDLTEEASSGITDGTILAMIQ
                     QQPKEMGRLAVEAVVKAIKGEKVEKNIPVPALLYDKENIKDFKN"
     gene            complement(17785..18675)
                     /gene="rbsK"
                     /locus_tag="PC465_002640"
     CDS             complement(17785..18675)
                     /gene="rbsK"
                     /locus_tag="PC465_002640"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HDF2649926.1"
                     /translation="MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQ
                     AISASKLGANVKMISCIGEDGLGEELIRNFRTNKVDYSLVSRNNHKSSGVAVITLCEN
                     DNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIKVL
                     LNPAPAVKLNEDIIEKVTYLTPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGAR
                     FYDGEEIKHVSCISVDVQDTTGAGDTFNGALAVAITEGKNLYTAVEYAVVVSGLSVTK
                     LGAQSGMPYKEDVEKYLNNK"
     gene            complement(18717..19730)
                     /locus_tag="PC465_002641"
     CDS             complement(18717..19730)
                     /locus_tag="PC465_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2649927.1"
                     /translation="MSITIKEIGELAGVSKTTVSKVINNKDENISQATREKILKIMKE
                     KNYVPNKLAQSLVTKKTNTIGLLIPDIRNPFFTDVSRGVEDKANEEGYNIILCNTDED
                     AKKEYEGIRTLSERMIDGIIFAASSNTNWKEANYKDIKIPTVLIDKKISMNKETLKGI
                     VKINNFEGAYIATKHLLDIGNKKIIYLSGPLQNEIAVDRLEGYKKALIECNLSYNPAY
                     VFEGKYKIEWGQEFIKNLEKIDFDAIFCANDLIAIGVIRGLKERGLSIPNDVSVVGFD
                     DIQTSSLISPSLTTVKQPSYDIGYKASEILINCLRGDKKESFDELIFKPELVIRDSTK
                     ESE"
     gene            complement(19959..20936)
                     /gene="bioB"
                     /locus_tag="PC465_002642"
     CDS             complement(19959..20936)
                     /gene="bioB"
                     /locus_tag="PC465_002642"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HDF2649928.1"
                     /translation="MEKYIIKLKNKVLREKEISYEEALNLISLDTNNKNDFDILLKSA
                     NEIREYFMGRKADLCTIMNAKSGKCSEDCKFCAQSSYYKTGVEEYSLLDYNEILNRAK
                     EMESKGVHRFSLVTSGKGMSGKEFNNILNIYEGLRENTNLKLCASLGIIDYEQAKMLK
                     SAGVTTYHHNVETCRDNFHNICTTHTYKDRIKTIKDAKKAGLDVCVGGIIGMNESEEQ
                     RLKMAFEIRELNVKSFPINILNPIKNTPMENYDVLEPMEILKTTAVFRFIIPNVYIRY
                     AGGRLSLKGYDKVGFNGGVNSAIVGDYLTTVGSGIENDKKMIIEQGFEL"
     gene            complement(21142..21405)
                     /locus_tag="PC465_002643"
     CDS             complement(21142..21405)
                     /locus_tag="PC465_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649929.1"
                     /translation="MKIYYEKENSKKANVNNIPSVFAFNFLRNFLTSKEYEETRKEYF
                     INNLTKSQVNQAMKDLKWLFREYEGLEVITMESLDGVKTRIVL"
     gene            complement(21475..22548)
                     /locus_tag="PC465_002644"
     CDS             complement(21475..22548)
                     /locus_tag="PC465_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HDF2649930.1"
                     /translation="MEKSKVYFCDLYSNSQNKNVPNNVRRLFDEAGFKDLIEKNDQVA
                     IKLHFGEKGNTTYMSPVAVRQVVDKVKDCEGKPFLTDTNTLYTGSRTNSVDHLTTAIE
                     NGFAYAVVNAPVIIADGLYSRNYENVKIDKKHFESVKIGGEIYNSSAMIVMSHFKGHE
                     AAGFGGALKNLAMGCASAAGKQMQHSDVTPVVKEKKCVGCGKCVNSCPTKAISIVDKK
                     AVIDSDVCYGCGECPTVCPTRAVTIQWESDSDVFVEKMAEYAYGAVSNKKDKVGYITF
                     VMNVTPLCDCVPWSGRPIAHDIGILASTDPVAIEQACYDLICKEMGHDVFKHEHPHVN
                     GTRIIDYACEMGMGSKEYELIKL"
     gene            complement(22796..23554)
                     /locus_tag="PC465_002645"
     CDS             complement(22796..23554)
                     /locus_tag="PC465_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2649931.1"
                     /translation="MREYIAFTKKEFKENLRNYKLFSLIILFLIFGISSPISAKFMPD
                     LIAHFAPTLKVTAAPTALDSWTQFFSNISGLGMSLTLIIFCNILSNEYSKGTLVIMLT
                     KGLSRSSIVLSKFSVTVIIMTIGFWLSFLFAYGYTMYFWPTANLNHIIFSAFNLWLIG
                     IMYISVLILGCVLFRPAFASVLLVLVATLLLSLISIPKQIAPYTPNFLMSKNIDLISG
                     KVAMPEFIIPIIITVLISVVCLLAAVILFNKKPV"
     gene            complement(23551..24468)
                     /locus_tag="PC465_002646"
     CDS             complement(23551..24468)
                     /locus_tag="PC465_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2649932.1"
                     /translation="MNIVSINGLSKGFGNRKIIDNLNFTVPEGSVFGFVGKNGAGKTT
                     TMKMVLGLLKPDSGTIDVCGEKVTYGKTSSNRHVGYLPDVPEFYNYMRPLEYLSLCGE
                     ITGLSKKEIQIRSEELLSLVGLRNEKRRIGGFSRGMKQRLGIAQALLSRPKLLICDEP
                     TSALDPVGRKEILDIMLKIKDSTTVIFSTHILSDVERICDHVAILNKGSIALSGTLSE
                     IKSMHGKDRLLLEFASNDEIQKFKSSDGIKSLLKDSEETNMEIVLHGKDIKAIQKTVI
                     STLAEMNLCPVKMELIELSLENLFLEVVK"
     gene            complement(24468..24668)
                     /locus_tag="PC465_002647"
     CDS             complement(24468..24668)
                     /locus_tag="PC465_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLDc_N domain-containing protein"
                     /protein_id="HDF2649933.1"
                     /translation="MENLMEYLPLLVPVIILDLILIITALVHVLRHPNYKIGNKAIWI
                     IVVLFISLIGPILYFTIGRGEE"
     gene            complement(24673..>25643)
                     /locus_tag="PC465_002648"
     CDS             complement(24673..>25643)
                     /locus_tag="PC465_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF2649934.1"
                     /translation="SYPDITFLPQLATYFNITVDELICYEPQMMKEDINKLYNKLCKD
                     FTVKPFDEVMDEIREIIKKYYSCFPLIFRMGLLIVNHYDIVDEKKRELLISEALEIFI
                     RIQETCNDIDICRQAKSMEATCYILLNQPIQVIDLLQNSNFPMINESILLAQGQMMNG
                     QMDEARETFQLGAYQNLISLVQNLVGILQNADKLQMKEIERRILAISDIFELDTLSPA
                     IMLSSYLTQAQINLIHGDNEGAIKSLRKYVDLATRDIYPIIIHGDDFFNKLDRWISEI
                     GTGITRDDTIVKAGIVAAIKNNPMFSVLSENKEYKFLIEKLSLLEE"
BASE COUNT         8396 a         4563 c         2653 g        10031 t
ORIGIN      
        1 cttaaaaata attcgtcaat acttttttaa attatttttt aaaaatattt actttcttat
       61 attacataat ttattgaatg gcagttatac tgttgtttta gagtatttta acacacacat
      121 tttgttgtaa aaattacaac tattaatata atatatatac aatcataagt attataattt
      181 ttatgaatct aatttaaact taatataaac ttattaataa atcttctata tctaaatttt
      241 aaaattacaa tataaaagct ctacactaaa taaatacatt aaataaacat aatgtgtaat
      301 gaatatagat ttatatatac aaaaacgctc caataaaaag gtaccaataa agttaaaaga
      361 aacttattga taccttttat tattatatac ttcaatatat aattataagt tttttgaata
      421 gtatggattt acatttatcc cttatctcat agctctcata gcatttacta ctgctataag
      481 tgccacacct acatcagcaa atatagcttc ccacatagta gctactcctc cagcacctag
      541 tatcataact ataattttta ctcctagagc aaatattatg ttttgccaca ctatcttatt
      601 agtcttgttt gctatttcaa ttgctttaga tatcttgcta ggctcatctg tcataagcac
      661 tacatctgca gcttcaatag cagcatctga acctaagcct cccatagcta taccaacatc
      721 agcacgagct aatactggag catcatttat tccatcacct acaaatgcta ttttctcttt
      781 ttcagttctt ccttcatata aatcttctaa tctatctacc ttttcattag gaagtaaatt
      841 tgagtaaact gtatccaatt ctaattcttg agcaatattt tttgctactt tctcattatc
      901 tccagttaac attacaactt cttttacccc tattgctttt aagcttctta tggcattttt
      961 actatcttct tttacttcat cagatataac tatataacct ctatatactt tatcaacagc
     1021 aatatagact actgtaccta cttctttagc tgatgaataa gatatatttt cttttttcat
     1081 aagtttctca ttacctgcta atataaaatt gccattatgc tttactctaa ttccataagc
     1141 tgctatttcc tcataactgt ctattgtatc taaatcaatt tttttattat agtaacttaa
     1201 tatagacttt gctattggat gatttgaatt tacctccgca atagctgcat attctaataa
     1261 ttcttcttct gatatacctt caggatttaa cttagttaca ttaaacacac ctttagtaag
     1321 tgttcctgtt ttatcaaata ctactgtatc tacacttctt aaagcttcta aatagttact
     1381 tcctttaata aggataccat ttttagatgc aaacccaatt ccactaaaga aactaagtgg
     1441 tattgataaa actaatgcac aagggcaaga aacgactaag aatatcaatc ctctatataa
     1501 ccaatcacta aatacctcac ctgagattac aagtggtggc acaaatgcta ttaataaagc
     1561 agctattact actatcggag tatagtatct tgaaaactta gatataaagt tttctgtctt
     1621 tgacttttta atgctagaat tttcaacaag gtcaagaatc ttagaaactg ttgattctcc
     1681 aaaactcttt gtaacttcaa tactcaataa agcattttta tttataacac ctgataaaat
     1741 ttcgtctcct ttttcaactt ctctcagtac tgactctcct gtaagtgcag aagtatctag
     1801 catagaaatt ccatccacta ctacaccatc taatggtact ttctcaccag gttttactac
     1861 tattatatcg cctacattta cttcttctgg tgacaccacc ttaacttcag aattaacttt
     1921 taaatttgca tagtctggtc ttatttgcat aagtgaagtt atagactttc ttgatttccc
     1981 aactgcaaca ccttgtaaat actctcctac tttatagaaa agcataaccc ctactgcttc
     2041 tgataactcc cctattgcta atgctcctac tgttgctaga gccatcaaaa agttctcatc
     2101 aaatactctt ccttttgata tatttcttat tgctcttaaa agcacatcgc cacctactat
     2161 tacataggca actataaata ctatattgct aaactgactt tcataacctg tagctgtttg
     2221 atatatacca aatatatata caagtgctcc aattataagt ggaattaatt ctttcttatt
     2281 tgtatcattt acagctcctg gtttttcagt agttctccct tttactttgt tagtagactc
     2341 tacttgtata tcaagccctg gctctgttga atttattatt tcttttattt tatttataac
     2401 atcatccgct tcaaagttat tacttatatt tactgtaagt tttttattta caaagtttaa
     2461 attagaagat tcaacttcct ttaatttaga aactttgtta ttaatttcct ctgcacaatg
     2521 tgcacagttt aatcctccta atataagctc ttttttaatt gatattttac tagatgcatt
     2581 ttctttagaa cttatttgta tatcaagacc tggttctgtt gaatctatta tatctattat
     2641 cttttctata gtagtatcct cattaaagct ttcctttata tttactgtaa gttttttatt
     2701 tataaaattt aaattagaag atttaacttc ttgtagttta gaaactttat tattaatttc
     2761 ttctgcacag tgagcacaat ttaatcctcc taggataaat tcttttttaa ttaaattatt
     2821 tgcttccata tatattcact cctctcattt atcatttata agtctctcta atatgattta
     2881 atccacaatc aaatatctga cttatatgac tatcatctaa tgagtaatac actgtttttc
     2941 cttctcttct aaactttact aatctagcct gctttaatac tctaagttga tgagatattg
     3001 cagagtgagt catatttaat aaactcgcta tatcacatac acacatttca tttgcaaata
     3061 atgcatataa tatctttact ctagtagtat ccccaaatac tttaaataat tctgctaaat
     3121 catataacat ctcttcatct ggcatagttg atttagcctc tgttactatt tcttcatgta
     3181 ctatattaca attacaatca tttatctctt ctctcatttt taatcctcca attattttaa
     3241 tatatgaata actgttcata tgttcattat atgctatcat ttctaaattt gcaacaataa
     3301 tttttattaa tttaatataa ttagaatgca catattataa acttttttaa tatatatatt
     3361 attagaataa gtttttgtaa acttttttat agttttctag gaggtgcaag tttaatatga
     3421 gtaacaagaa aaaaaaggat ttagatacta gttacatgcc ttacttagac ccagcgaact
     3481 atgcagatta tattactaat gaagaaattc ctcaagatga attgagaaat gaccctcaaa
     3541 tttctaatgg ttatacaaaa atacctaata accagaacat aaataaccta tatcctaata
     3601 atgtaaatca ttatcctaaa agtagtaatt ctccaaacaa cttgcctaac acaaataata
     3661 catccggaaa tatgaattac aatacgtctg ctacaaataa tatgcctaat aacatgaata
     3721 ataatacggg tatgcctaat aatatgtcta acaatatgaa tagtaatatg ggtatgccta
     3781 acaatatgcc taataacatg aatagtaaca tgggtatgcc taacaatatg cctaataata
     3841 tgaatagtaa catgggtatg cctaataaca tgaatagtaa tatgggtata cctaacaata
     3901 tgtctaataa tatgaatagt aatatgggta tgcctaacaa tatgtctggt aatatgaata
     3961 atatgtatgg taatacaagt atgcctaata acatgaacag taatatgggg tataatatga
     4021 acaatactat gagtattcct aacttctcat gtaatcaaaa tatgcctcct aatgtactta
     4081 tgatgatacc aggagttata tgtcataata caatgcaagg tatgcctgta gttatgccta
     4141 gtactatgcc tcctaatata tatcctactc cttatggttc tagtaatatg tctatacaag
     4201 gtataccaca gactactaat attgaagaat ttgatgagga agaaatgtaa tatatatttt
     4261 tttaagtaag ttgtataaaa cattaataat tgaccataat aataaatgta ttcctcataa
     4321 tattccccca atattataga aataaattta agcgagatta aattcagtta atctcgctta
     4381 aataatgtct aaatttatta ttccaaaaaa tcatcaaaat ctaatgaacc tgattctgca
     4441 aagtcatata atgcattttg ttcaaagaaa aatttctctt caaatttaat atagtcacta
     4501 taattagatt gacttatttc attgatataa ttgcaatcat tttcgttata agtaccaata
     4561 aaaaacttat ttcccattaa gtaatatata gctttcatat cattatttat tatatataca
     4621 ttttctttta catgatcatt attaaaatta aatctagtaa aaaatatacc ttcattcata
     4681 ttacttttta acaaaaatgg attttctcta taaaatactc ttgcaaattc ttcaggtgaa
     4741 tttacactgt atacacttac aaattcactt ttagaaatct catcaaatac ctcaaaatca
     4801 tacataggtt ctttatctgt cactaataga gagttaattc taaaaccagt ttcataacac
     4861 ttacttatgc aaaaagcaat tttacatata tagtatccat cattatcttc atataaagct
     4921 tcacttatat atctgccttg acctttatca cttaccacat ttttaagtaa tgttccattt
     4981 atattagtaa tatgcatatt tgcaatctcg tcacttccag aaaagtactt taaactttct
     5041 ctatcccatg ctataaatct catagtcata taatttataa attcaacttc ttcatcaact
     5101 cttttacata ttttattgta taatttttct atagttaaat ctgttttata gttttttata
     5161 atatcaatat actcacattt atctcctggc aatagcttat cataataaag attcttatta
     5221 ccaaaataag atactaaaaa taaagattca tccttcgtta attcaactct atctgaacca
     5281 aatcctccca tcaatctttc ttcttccata taagcttctt cttgtgttgg gttatttaaa
     5341 ctcacataat ctgctaatcc taatccctct gcatctaata aaaaatattg acaaaagtga
     5401 ttgttttcat catctatcca atttattata agacctaaac ttcccataag tctagaattt
     5461 gtagcctttg caaaattaaa attcatatag tcacatcctt taaactctaa aatacttgtt
     5521 ttttaatata taaattatta tacatatatt ttaacaactt agatacaatt tataatataa
     5581 tataaggaaa tgattaattg aggtggtctt atgaaaaata tagcagcttt ttttgatata
     5641 gatggtactc tttatagaga ctctcttatg gttgaacatt ttaagaaatt aattaaatac
     5701 gatataattg accaaaaaaa ttggtataaa catgctagag acacttttat ggattgggat
     5761 aaaagacaag gtaattatga tgattatcta ttagaaatat gtgaccttta tgttgattca
     5821 ttaaaaggat tagataaaac ctgtatcaac tttacaagtg accaagtaat taaattaaaa
     5881 gcagatagag tctataaata cacacgttca aggattgagt ggcatctaaa tcaaggacat
     5941 atagttatat ttatatctgg tagccctgga tttcttgttg aaaaaatggc aaaaaaatat
     6001 aatgtaaccg attttctagg aagtgattat gtctttgaaa ataatatatt tacaggcaca
     6061 gttattccaa tgtgggattc tataagtaag aataatgcta taaacgattt tgttgtaaag
     6121 tatgatttag atttatcaaa ctcgtatgcc tatggagata ctaatggtga tataaatatg
     6181 ctaaaaagag ttggaaatcc aatagcaata aatccaacaa aggaactttt atctcaaata
     6241 tcacttgatg aggaaatttc taaaaatgtt gagataatag tagaaagaaa agatattatt
     6301 tattctctat ctacagatgt aaatatagtg gatatttaat ttatactatc tattttaaaa
     6361 acttatatta tatctaatat ttatatctaa catataaaag ctttgactaa aaatcaaagc
     6421 ttttatatgt tgcactaaga atatattaaa tttagcttta tgttttaatg tatattcata
     6481 tatataattt accttatcca aactacaatt tcattaaatt taaagataaa aataagcaat
     6541 tattttttaa atagcatctt tcttaaccta ttattgtaat aacctataaa agaactgtaa
     6601 acatagtcat atactataaa ggctatctca aatgaaccta taataaatat gtttattgga
     6661 atataaacta ttgttcttaa taaaaaatac aatataagta tcattatatt tgcaaatact
     6721 aatttcataa aatactcaat atatatagac ctatcttttt ctataagata ttttacaata
     6781 ccatatattc caaaggtaag tgaatataca atccattgag acttacttgc catcactata
     6841 aatcctaaaa ctatagaacc tatataaaaa gcgattccac tcttaaagcc ccattccatt
     6901 attacaattg atactaaaag tgatgctaac cccataataa acaatgtatt tacaggaata
     6961 atatttgtaa gagtcaacaa tatcacattt aatgctaata aaactcctcc ataagcaact
     7021 tttatactca tatttatcat cctaacaaca agttattaaa tctccaccaa aacattcaca
     7081 acatgaatct aaacaccaaa gcttagcaca attttcacaa caatcgtcac ctagacaaca
     7141 acagcaatca tcacagcaac agcaacaaca tccatctaaa tcattacgtc ttcttctatt
     7201 ataattgtca gccctattgc tataatcatt tctatattgt gtataacttc taagtgcatc
     7261 actatattca ctattttcag gctccataaa ttttgctctt tttaagaagt cttcaccttc
     7321 ttcataatat cctatgttca ttgcagaaaa accagttaaa taataccact ctgcacattt
     7381 gtcagtcaaa gtttttaaaa aatcatatgc ttttttaaat tcactatttt ctatgaatga
     7441 tcttgctctc ataaaatttt cattattata agtattactg tacattcttt ccacctctac
     7501 tttctaatat attaatatat cttaaataaa caccagaata aattatattt tctattattc
     7561 caacattttt atttagattt agattatcaa ttcccctagc taaaaatcct aatgatgtta
     7621 ctattatttt ttttactttt tcttttaact catcattttt atcaatatac tctataaatg
     7681 gattatatct tcctttctta aaatcttcat ctaaatcttc ataggcatct agtagatata
     7741 tatacttacc tatattaaaa cctatcattc ttaagtttct ctcattttca tcttttttat
     7801 agacaaatac ttcacccatt atatttccaa atatactaga tacttcatct atatttatat
     7861 ttttatcttt ttctaactta tttaattcat ttagttgttg ttttatatac tctgcttttt
     7921 caggatactt ttcatatgct aattttaatt tgtttttata tatataatat gccaatttat
     7981 cttttatgcg tttatcatcc attaaattat cttccaattt ataatacgtt aaaagaatat
     8041 tcatacttgc tgcatattct gtaatatcat ttgtaattac ctttttcttt ttaaatggat
     8101 ttactataca cacttcctct gtacttatag actctgggtt atatactgct gttaataaaa
     8161 caattaaaaa tgttatatca tagttcaaag aaaacctaga gatttctcca tgatttcttt
     8221 ttaagtattt acatagtcca caatagtaag ctttgtaata atcatattct ctaaatgtta
     8281 aatccatttt gtttatttta acatatccaa acataaatac tcctttttgt actactttat
     8341 tatataaatt atatttattt tctaactcat ttattttata gtgcattatg taagttttta
     8401 ctctttttac ttactgatgc tatatagtcc ttttgactta ctacatatta tctctaagtt
     8461 acttatatca tttaatagta tattctttgc ctttgaacaa gtcatttttt atcccttatt
     8521 atttaaggtt caatcaagat ttaacaagct atatatttac attttttgta agtctaacat
     8581 aattaatata ttaaaaagat gtatttatcc tatatgttta tgtgttaatt agactttagt
     8641 aaccttaatt gaatctattg tttcattggt tagaaaatga gtgtatgcca tcaaacatta
     8701 actcgctcct cttttatttt ttgttaatta ttattatatc attaataaaa ttataattca
     8761 tttattttat atgtaatcat taataaattc ttatctactt ctcttttctt ttttaagtct
     8821 tctatattcg tctaagaatg ttctgttagg tatagttact taattacaat ctcatctatt
     8881 gttatactta catctttatt ttgctataag ctatcattta ttacctattt cttcttattt
     8941 tttctatttt agtggacatt taatttatga caaataaata tatttatttg attatattta
     9001 atacaaaact attcttataa cctttttaaa tcatatttaa catataatat taagtaacat
     9061 acttacttaa gaggaattat taaatgataa aatttgaaaa gttaaatatt attaacaata
     9121 aagatatgaa agaaatacta gatacatggg aatcatcagt aagagcaaca catgactttt
     9181 taagtgaaga aaaaataata tcaataaagc ctcaagttaa agaaggtgct aaatatgtta
     9241 gtaatttttt atgtgtaaga gacaaaaaag gtcttataaa agcttttatg ggaatacatg
     9301 attttaaaat tgaaatgtta tttgtaggta attatagtat aggaaatgga attggaaaaa
     9361 gacttgcaga atatgcaata gaagtattaa atgtaaatta tgtagatgtg aatgagcaaa
     9421 atcaacaagc attaggcttt tataaacata tgggatttaa agtctttaaa aaatctgagt
     9481 tcgatgaaca aggtaatcca ttccctatac tgcatatgaa attaaaataa caatataaac
     9541 tatagtataa ctaaataaat ataaatagag taataattga aaaatattac tctattatca
     9601 taaccttact ctcacttatc ttgttataat aattatataa tatattttta ggtcgtttaa
     9661 actgtatttt tagtttttaa ataacaaata ttttctattg ttgatttcca atgattttat
     9721 acaaaaatag tataattgtt atatgttact atagaagttt tatttatttt tcttactgtc
     9781 taatactact ccaataacta atccaaagga taaaccaata gctaagtttt taaataatga
     9841 acccaaaata acaccaaaac ataatcctaa cgccaaataa cttatatttt catttttcat
     9901 atattactcc tttaaattta attgtaacat tttaactttt ctaattgatt cttttgaagt
     9961 tttgactata tcaactaaac ctcttatctc atagttatta cactcactta gcactccttt
    10021 tactaatatt ttaagatatc tcccctaatt tataaacagt agtagtaaaa aatggttttt
    10081 aaacatatat tttcaaagtc taatatatat aaaactattt ttatgaatct ttactaattc
    10141 caactgctct taaaggaccg agtaacgaca ttctaacaag tatcagtacc atttcttcag
    10201 ggtaatctat aacctaacta aacctaaaaa ataaaattaa ttataaacaa aaaataaata
    10261 taataaaagg gcttacaaat tataagtcct tttatcgaac ataaaatcaa attattttcc
    10321 ttaaatagga aactttaaaa atatattcta attattatat cttagattga aaataattag
    10381 aaagttaagt taaaaataat gttaatttat atatttatcc taattcatac aattcaatct
    10441 tacttgtatt aaattactct tcaaataatt ggagtatatt caaaactacc tacagtatac
    10501 ttcaattctt tttttgcttt atttataacc aattcatcaa gcattacatc atttattgaa
    10561 catgatatag atttagatgc caataacatt gctttaaatc ccatatcaga acctgcactt
    10621 gcacaagatt gccatgtatg ggcagaaata ccaataggcc aaactgaaca agaacactgt
    10681 gctgtaggaa ttatgtaact aacatctcca atatccaatg ataatgatat acagttatta
    10741 tgagtaaatg tatcatctgt aacctcatca tgtaaattca tcttagtaat atccttattt
    10801 ccacttaata cactagaaac actacttctt ttatctatag acactgtctc agctaattta
    10861 tctgcaaaat agtagtcatc ttcattatag ttttgtacac ctactaattt catattttgt
    10921 gatagaatat ctgttaatat tgtatttgga atatagtcat atactccact tataatgtca
    10981 tattccataa tggtaccagt cattaatgct gctccttttg ctatatcaac aatcctacca
    11041 aatacatctc ttacatgctc cattttaact cctcttatgt aataccacac ttctgcaaaa
    11101 tcaggaacta tatttggcat ttttccacca ttagtagtta catagtgtac tctacaatta
    11161 tcaaatatat gttctcttaa ataattacaa cctatattca taagttctac tgcatcaagt
    11221 gcacttcttc cgttataagg agcttgtgct gcatgagcac taatcccatt atatctaaat
    11281 ttcacagagt aattagcaag tgttgggatt cttataggag tatttatatc aaatggatgc
    11341 caactaaaag cacaatcaat tccatcaaaa aaaccctttt ttatcatcaa tacttttcca
    11401 gataaatctt cctctgctgg acatccatag tattttatag tccctttcag cttttttagt
    11461 ttgattaatt cctttactgc aattacagct cctattgaac ctgtaccaag taagttatgt
    11521 ccacatccat gacctgcacc accatctaca ataggttctt tagtagtgga tactttttga
    11581 gacaaaccat ctaaagcatc atattctccc aaaactgcta taactggtct accttctcca
    11641 taactagcca caaatgctgt atccatacct tctaatccct ctatactaaa accatgtttt
    11701 tttaaacatt ctttttgtaa atttgaagca tagtattctt tatactgaag ctctggattt
    11761 ttccatatct tatctgatat atctcttaat tctccctgta tctcatctat atattccatc
    11821 aaaaactttt tatttaaatt atccatatta attatataaa cctccctgtt tctaataact
    11881 tatagattat cagccaaaat gactaatttt aactgattta aaaatatttt ctaccataca
    11941 accattttat acaataaaac ctcttgactt gtaagtttca ttttatcaag taagaggttt
    12001 tcaagtttta taaaattttt agcatgttaa ccaatcaagc atattaaccc ataatttatt
    12061 atagtatttc caatcagtaa attcttttgg accccagtga ggtgcacagt cagaactaaa
    12121 gatagcagat tttccttttc caaactcgcc aacagctaca aatgggtctc ctccaatagt
    12181 tgctaaaaca ggacaattat ctctagctac tgttttgtta tatcctaaaa actttggcca
    12241 ttctgttggt atacctttta atactggatg ttcagagtca ataacttctg gaattattcc
    12301 tgctggtttt tcaactctat catctttatc tatcattgtt attggtaata catctttgat
    12361 agcagtttct ccgaatctag cttttgcatc tattcctgta aatgacatat atccacctac
    12421 catgattaac gccccaccat tatttacata ctctttgatt agttcaagtc tatctggatt
    12481 actattgcaa tctataaaag tactattaga taataagaac gtattagaac ctatatcaga
    12541 taatattata cagtcatact catttaactc ttctaattta tacggaaaac tatctgctgc
    12601 tacatgtgca ggcatatgaa ctgtctcata tcctccagat tctattgctt ctttcaacca
    12661 ctttacagct tcttcataat gagttgtaac aaacgtatca aatcctttta tatgagttat
    12721 attttttacc caagattccc ctactattaa tacttttttc atttatatat tcctcctact
    12781 tttataagtt taatattaga cttgcataca taagtatact atctaaatac tccttaattt
    12841 caacatattc atcaattgaa tgacattgtt ctattgaacc tggccctaat ataagtgttg
    12901 gtatttcagc taaatttttc attactctcg catcattgcc agctgttgaa ccttttatct
    12961 ctaatttttt tcctagagtt tcttctagta ttttatgtgc attcactaca aaatcagaat
    13021 ccttgtccat ctcaaaacct aaccctgatt gatatatgtt tatatttggt ttattatctt
    13081 taagccataa atctccatta gcccttgtca ttatgacatt tgttacatca tttacaactt
    13141 gttcataact cattatattt ggcaagaagt gtacacataa attaaataca cacttatctg
    13201 gcacagtaga acctgctgtt ccaccattta ttacacctaa atttattgta ggtgaaggta
    13261 atagtggatg tttatatatc ataagccagt tatgttccaa cccttttata tcttgaagca
    13321 acaacatagc cttctcaatt gcatttacac cctcccactt actaccacag tgaagagaca
    13381 cacctttaac ctcaacttca aagaatacaa atcccatatg tgcaactatt aagttttgtt
    13441 ctgatggttc acaaattatg caacaatctc caccaatacc attcataact gcatttatgg
    13501 taccatttcc gccaccttct tcatctacta ctgacattat ttttacatta ccaggtacat
    13561 ttagaccact atcttttata agctttacag ctaatattga tgctataagt ccagatttca
    13621 tatcagcagt tccaagtcca taaagttttc cattatcttc tgtagcacga tatggattat
    13681 atttccactt acttatatca cccggtggca tagtgtctac atgaccatta aatacaattg
    13741 tcttaccagg taaatcatca ctatacttac aaattaaatt atatctatct tgataattgt
    13801 gacctagatt tccttcttta tatatatttt ttgctttttt aattaattct tcgcttattt
    13861 cttgtctatc tacactaaaa cctatgtaat ttgcaagttt ttcaatatat tcctgtcctt
    13921 ctttttcaaa tccacctagt attccatgac caacatcttc agtctttata cttacaagtt
    13981 cttttaaata atctatgtat tcttgttttt tactatttaa tgtatctaag agaatttttt
    14041 tcatatttcc tcctaagatt tatttttaca tttaaaattt caagtctaat ctcatctatt
    14101 taagccatag taaacttttt cacttagcat attcccattc aatgtataaa gatgtatgca
    14161 aattaaagta taaaaatata tacaaaaact caataatttt tatagtttat aagctaaaat
    14221 ttaattacta tttagattta gctgattttt ttaattttat attatttatc catatagcaa
    14281 ataacattac caaacctttt ataatcattt gattatatga agatacactt aataagttta
    14341 atccatttcc taatattcct attattccga cacctataca tgtacctact atagaaccag
    14401 aaccacccat catattagta ccaccaagca caacggctgc tatagcatcc aattctgctc
    14461 catctccaac agttggtgaa cctgatgcca aacgtgatga tagtattatc ccagctaatg
    14521 ctgttagtag tccagctagt gcgtatactt ttactataac tttatttact tttactccac
    14581 ataatctagc ggcctcttca tttccaccta ctgcatgtac atgacgtcca aaattagttc
    14641 tttttaatag aaaatgtcct gctattacaa ctataatcat aattataact ggtattggta
    14701 ttggtccaat atatcctcta ccgagcatct taaatgcatc tgtatttact gatataggtc
    14761 ttcctcctgt aaatacaaag cttgccccac ttattatcgt taacatggct aaagttacaa
    14821 tgaatggagg tagtttttgt gttgaaataa ttgcaccttt tatgactcct aatattgtcc
    14881 ctattgctaa tgcaagtatc atacctcccc atataggtgc attataattc actactgttg
    14941 tagcccaaaa tgtacctact aaagcaatta ctgctcctac acttaaatct attcctcctg
    15001 taattattac aaatgtcata cctactgcaa gtattgcatt tattgatatt tgtcttccaa
    15061 cattaattaa attgtctaaa gttaaaaagt tagatgaagc tacactcatt attataaaaa
    15121 ttattacaag tcctacagct gcactccctt ggtctctaaa tacacttgtt aattttgtca
    15181 ataatggaga agatttttct tctttatgct tagttattga actcattaat tttacctccg
    15241 aaagccaatt ttaatacatt attttcaacc atttcttcac cttctaaaaa tccacttata
    15301 tgaccttctc tcataaccat tattctgtca ctcattgata ttaattctgg tatttcagaa
    15361 gatatcatta ttatacttac accactctcc actaaatctc ccattagatt gtatatctct
    15421 gccttagcat ttacatctat acctctggtt ggttcatcca taattaatat atctggttgt
    15481 aataaaagcc atcttgctat tatagctttt tgttggtttc caccacttaa actttgtata
    15541 acttgattca tatgtggtgt ttttatcttt aaagcttcta tgtatttttc taaaatatct
    15601 ttttcctttt ttctatctat aattgattta aacttagata tcttttttaa cccagccata
    15661 gttgtgtttt ctttgacact catttgtaaa aacaatccag taccttttct atcttctgtt
    15721 attaatccta gtccattttc tattgcatct gatggagttt taaactttac ttcttcattg
    15781 tttaaatata ttttcccaga atcatatgtt ctaagtccaa atatagcttc tactatttca
    15841 cttctcttac ttccaactag tccacctatt cccaatattt caccttttct tatattaaag
    15901 ctaatatcat taaaaacatt gttcttagtt agactttcca ctcgcataat ttcttctttt
    15961 atttctactt ttctttttgg gaaaaattgg tctagctttc tatctatcat taaattaact
    16021 aattcttcct cagacgatac atctttggta ttcaaagtcg aaatcgtttt cccatctcgc
    16081 attatagtta ttctgtcaca aatctcaaag agttcttcca tcctatggga tatatatatt
    16141 atactaactc cactctcttt taaatcattt ataagtctaa aaagtatttc agtctctttt
    16201 ttacttattg aagaagtagg ttcatccatt attaatactt tagtttctga tgataaaact
    16261 cttgctattt ctaccatttg tttttgagct atactaagct ctttgactaa gctatttgga
    16321 tttatatcta ttcccatatt atcgaaaatc tttttagcct cttcattcat ttttttgtca
    16381 ttggttaaga ctttgccatt tatttctttt cccataaaaa tattttgtgc tactgttaat
    16441 tcgtcaaaaa ctgttagttc ttgatatatg gcatttatac ctatcttttt agagatatct
    16501 ggggatatat tctctatttc tttgccttca aaaataaatt ttccagaagt tttcgaatgt
    16561 gccccagtta aaatctttat cattgttgat ttaccagcac cattttcacc cagtagtgca
    16621 tgaacttcgc catgaaataa ctcaaaatta acattatcta atgctctgac accaggaaat
    16681 tctttagcaa tattacttaa cttcagaatt atattactca taatgacact cctttttaaa
    16741 taggatttct ttcaaataat ctcattttat tttactaatt cttaaagtct tttatatttt
    16801 ccttatcata aagtaaagct ggtactggta tattcttttc taccttttcc ccttttatag
    16861 cttttactac tgcttctaca gctaaacgtc ccatctcttt aggttgttgt tgaatcatag
    16921 caagaatagt tccatctgtt attccacttg atgcttcttc agttaagtca aatcctacaa
    16981 tcttaacatc cttatttttt gcagattcaa gtgcagcttt agctcctagt acactatttt
    17041 cagctgttgc atatattata tctacatctg gattagattg aattaagttt tctactgtat
    17101 taagagattc ttctctgtca tatcctggtt gtgaatttaa tatcttaaca tttgctgaac
    17161 cttttaatgc atctttaaat ccatctattc tctgcatttg tatttgagat tttaaatctg
    17221 tcactattgc tatttctgac tttccaccta acttttcatc tatgtatttt ttagtgtatt
    17281 cccctaattt tttaccagca tcataactaa ctgttcctac ataacttgta atattttcag
    17341 tatttaatac agcatctact gtaactactg gcattttttc aaatgctcct tctactgctg
    17401 gtactatagc cgaattatca gttccaagta ctatcattcc atctacattt tgttgtataa
    17461 aatcttctat tgctgatgtt tgcttagcta catcttggtc tgggtcattt actataactt
    17521 tcacacctaa ttctttagct ttttctttta ttccctcatc aatatctata aaaaattgat
    17581 gttgaagagt tattgtagat actccaatag ttaaatcttt cttgtctgaa ccacctttat
    17641 tatctgattt acttggtcct tccattgaac accctgttaa cattcctatt gctagtattc
    17701 cagcaattcc taaagataaa atttttctca ctctcataat taacctccat ttttaatagt
    17761 tttaaatttg aacaaattag atttttattt attatttaaa tatttttcaa catcttcttt
    17821 atagggcata ccagattgtg cacctagttt agttacagaa agacctgata ctactactgc
    17881 atattctact gctgtatata aatttttccc ttctgttata gccactgcca atgctccatt
    17941 aaatgtatct cctgctcctg tggtatcttg aacatcaaca cttatacaag atacatgctt
    18001 gatttcctca ccatcataaa atctagctcc attttttcct tctgttatta caagtttatt
    18061 tggatatttt tttaatactt cttctatccc ttcatttgtg tcaaaaacta tcttatattc
    18121 atgttcattt ggtgttaagt aagttacttt ttctattata tcttcattta gttttactgc
    18181 tggtgctgga tttaataaaa ccttaatcct attttcaaaa cagaaattca ctacataatt
    18241 tattgttttt aatggaatct ctaattgtag caatactata tctgcattct ttatctcttc
    18301 ttcattcttt ttaattaatt ctatatctac tagctcattc gtccctggta caacaacaat
    18361 actattatca ttttcacata atgttataac agcaacacca gaacttttgt gattatttct
    18421 ggatactaaa ctataatcaa ctttattcgt tctaaaattt cttattaact cctctcctaa
    18481 gccatcttcc cctatgcatg atatcatttt tacatttgct cctagtttag aagctgagat
    18541 agcttgatta gccccttttc ctccaggtga tgtaaaaaaa ctattaccta atactgtttc
    18601 tcctttttct ggtcttttat ctacagaaca taccatgtcc atgtttacac ttcctatgac
    18661 aactatgttt cccattacat tactccttta catatctatt tatgtctctc gtgctgttat
    18721 tcactttctt ttgttgaatc tcttatgact aattctggtt tgaaaatcaa ttcatcaaac
    18781 gattcttttt tatctcctct taaacaattt atcaatattt cactggcttt atatcctata
    18841 tcataagatg gctgttttac tgtggtaaga gaagggctta ttagacttga tgtttgaata
    18901 tcatcaaatc ccacgacact tacatcattt ggtatactta atcctctttc tttaagacct
    18961 cttatgacac ctattgcaat caaatcattt gcacaaaata ttgcatcaaa atctatcttt
    19021 tctaaatttt ttataaattc ttgtccccat tcaatcttat attttccttc aaatacataa
    19081 gcaggattgt agcttaaatt gcactcgatt agagcctttt tatatccttc taatctatct
    19141 actgctattt cattttgaag tggaccactt aggtatatta ttttcttatt tccaatatct
    19201 aataaatgtt ttgtagctat ataggcccct tcaaagttat ttattttaac aattcctttt
    19261 aaggtttctt tgttcatact tatcttctta tcaatcaaga cagttggtat ttttatatct
    19321 ttataatttg cttctttcca gtttgtattt gaagatgctg caaatataat tccatctatc
    19381 atcctctctg atagtgttct tattccttca tattcttttt tagcatcttc atctgtatta
    19441 cataaaatta tattgtagcc ttcttcatta gctttatctt ctacacctct tgatacatct
    19501 gtaaagaatg gatttcgtat atctggtata agaagcccta tagtattagt ttttttagtt
    19561 actaaacttt gtgctaattt atttggtaca taattttttt ccttcattat tttcaaaatt
    19621 ttttctcttg ttgcctgact tatattttca tctttattat taatgacttt tgacacagtt
    19681 gttttagaaa caccagccaa ttcgccaatt tcttttatag ttatactcaa gaagttcacc
    19741 cccaaaattt aggaaaccgt tttacttaac cggttaccta gatactatca catctttttt
    19801 tcatttgcaa ccattttata taaattttga tatttttccc ttttttcaaa atattgcaac
    19861 ttataattca attttaatat ttaaattaat ctgcaaaaaa aaattaatat acttttataa
    19921 ttatctaaaa gtatattaat taatttaagc agtatttatt aaagttcaaa tccttgctct
    19981 ataatcattt ttttatcatt ttcaatccca cttccaacag ttgtcaaata atcaccaaca
    20041 attgcagaat ttactccccc attaaatcca actttgtcat atccctttaa tgatagcctt
    20101 ccaccagcat accttatgta cacattagga attataaacc taaatactgc tgttgttttt
    20161 agtatttcca ttggttctaa tacatcataa ttttccattg gtgtattctt aataggattt
    20221 aaaatgttta ttggaaatga ttttacattt aattctcgta tttcaaaagc catttttagt
    20281 ctctgttctt cactctcatt cattccaatt ataccgccta cacatacatc tagcccagct
    20341 tttttagcat cttttatagt ttttatccta tctttatatg tgtgtgttgt acatatatta
    20401 tgaaaattat ctctacacgt ctcaacattg tggtgatatg tagtcacacc tgctgacttc
    20461 aacattttag cttgctcata atctataata cctaaagatg cacataattt taaattagta
    20521 ttttccctca atccttcata gatatttaaa atattattaa actcctttcc tgacatacct
    20581 ttaccacttg taaccaatga gaatctatgc actcctttac tctccatctc tttagctcta
    20641 tttaagattt cattgtaatc taataatgaa tattcttcta caccagtttt ataataagaa
    20701 gactgagcac aaaatttaca gtcttcacta catttgccag atttagcatt cattatcgta
    20761 cataaatctg cttttcttcc cataaaatat tctcttattt catttgcaga ttttaataga
    20821 atatcaaaat cgtttttatt atttgtatca aggcttatta aattaagagc ttcttcataa
    20881 cttatttctt tttctctcaa tactttattt tttaatttta ttatgtattt ttccatatat
    20941 cctcctattt gtcaacttaa tatttttatg tagtttactt attatatata gtattgcata
    21001 tataacattt attggtcaac tttattttat acacaagttt actatacaca aaaaaatact
    21061 gcttcaaaat aatattagta tatggattat acatattatt attaaagcag tattttttat
    21121 tagaatataa ttcttactgg tttataaaac tatccttgtc ttaactccat ccaagctttc
    21181 cattgtaata acctctaagc cttcatattc tctaaatagc cattttaaat ccttcatggc
    21241 ttgattaacc tgactttttg ttagattatt tataaaatat tcttttctag tttcctcata
    21301 ctctttgcta gtcaaaaagt ttcttagaaa attaaacgca aatacacttg gaatattgtt
    21361 tacattagcc ttcttgctgt tttccttctc atagtaaatt ttcataaatg catactcctt
    21421 tgatactttt agatttctct tacaataatt atatgcattt aagtgctact attcttataa
    21481 ttttattaat tcatattctt tacttcccat acccatttca catgcatagt ctattattct
    21541 agttccattt acatgaggat gttcatgttt gaaaacatca tgacccattt ccttgcaaat
    21601 caaatcatag catgcttgtt caatagctac agggtctgtt gatgctaata ttcctatatc
    21661 atgggcaatt ggtctacctg accaaggtac acaatcacaa agtggagtta cattcataac
    21721 aaaagttata taccctacct tgtctttttt atttgatact gctccataag cgtattctgc
    21781 catcttttcg acaaacacat ctgagtcact ttcccattgt atagttactg ctctagttgg
    21841 acagacagtt ggacattctc cacatccata acatacatca gaatctataa ctgctttttt
    21901 atccactata cttatagctt ttgtaggaca agaattaaca cactttccac aacctacaca
    21961 cttcttttcc tttactactg gagtaacatc agaatgttgc atttgttttc ctgctgcact
    22021 tgcacatccc atagctaagt tttttaatgc tcctccaaaa cctgctgctt catgaccttt
    22081 aaaatgactc attactatca ttgcagaaga attataaatt tctccaccta tttttacact
    22141 ttcaaaatgt tttttgtcta tttttacatt ctcataattt ctactatata atccatctgc
    22201 aattattact ggtgcattta caactgcata agcaaatcca ttttctatag cagttgtaag
    22261 atggtctaca gaatttgttc tactccctgt atacagtgta tttgtatctg ttaaaaatgg
    22321 ctttccttcg cagtctttaa ccttatcaac cacttgtcta actgccacag gactcatata
    22381 tgtagtattt cccttttctc caaagtgaag tttaattgcg acttggtcat ttttttctat
    22441 taaatctttg aatcctgctt catcaaataa tcttcttaca ttgtttggta cgtttttatt
    22501 ttgcgaattt gagtataaat cacaaaaata tacttttgac ttttccatat ctacacccct
    22561 ttaaaatatt tacttatact aattttatca cttttaaagt aatttttagt atattttaac
    22621 ataattaaat attcttatat ttatttgata caaataatat tatttgtatt attttctaca
    22681 cttaattcta tatattaaaa atcaaaaaga cttgaaactt aagtccaagt ctttttgatt
    22741 tttaggtgta gtttttaaca acataagatt actttacctt gtgataaagg tattattaaa
    22801 ctggtttttt attaaataaa ataacagctg ctagtaaaca tactacagaa ataagaactg
    22861 ttataataat tggaataata aattctggca ttgccacttt ccctgaaatc aagtctatat
    22921 tttttgacat caagaaatta ggagtataag gtgcaatctg tttaggaata gaaattaaac
    22981 tcaataaaag agttgccacc aatacaagta aaacactggc aaatgctggt ctaaatagta
    23041 cacacccaag aattaataca ctaatataca taattcctat aagccataaa ttaaatgctg
    23101 aaaatataat atgattaaga tttgcagttg gccaaaaata cattgtatat ccataagcaa
    23161 ataaaaaact caaccaaaaa ccaattgtca taataatcac cgtaacagag aatttagaca
    23221 atactataga tgaacgtgat aaacctttag tcagcataat aacaagtgtc cctttagaat
    23281 attcatttga taaaatatta caaaaaataa ttagagttaa actcatacca agaccagaga
    23341 tattgctaaa aaattgtgtc caagaatcta aagcagttgg tgcagcagta acttttaaag
    23401 tcggtgcaaa atgagcaatc aagtctggca taaattttgc agaaatagga ctacttatac
    23461 caaatattag aaataaaata attaaactaa ataatttata atttcttaaa ttctctttaa
    23521 attctttttt tgtaaatgct atgtattctc tcactttact acctccaaaa ataaattttc
    23581 aagtgataat tctattagtt ccatctttac tggacaaaga ttcatttctg cgagtgtaga
    23641 tataactgtt ttttgtattg cttttatatc tttaccatgc aaaacaattt ccatattagt
    23701 ttcttctgaa tcttttagta aggatttaat accatcacta gacttaaact tttgaatttc
    23761 atcattactt gcaaactcca gtaaaagtct atcctttccg tgcatacttt ttatttctga
    23821 aagtgtacca ctaagggcaa tgcttccttt gtttaatata gcaacatggt cacagattct
    23881 ttcaacatct gatagtatat gtgttgaaaa tattacagtt gttgagtctt tgattttaag
    23941 cataatatct aatatttctt ttcgaccaac agggtcaagt gcacttgttg gttcatcaca
    24001 aataagtaat ttggggcgtg aaagcaaagc ttgagctata ccaagtcgtt gcttcattcc
    24061 acgagaaaac ccacctattc gtctcttttc atttctaaga cccacaagtg ataacaactc
    24121 ttcactcctt atctgtattt ctttttttga aagtcccgta atttcaccac aaagagaaag
    24181 atattcaagt ggtctcatat aattgtaaaa ctctggaaca tcaggcagat aacctacatg
    24241 acgattagaa cttgttttcc cataggtcac tttctcacca caaacatcta tagttccact
    24301 atctggttta agtaacccaa gtaccatttt cattgttgta gtcttacctg caccattctt
    24361 acctacaaac ccaaagactg acccttctgg tacagtaaaa tttaaattat ctattatctt
    24421 tcgattacca aaaccttttg ataatccatt tattgagaca atattcatca ttcttcacct
    24481 cttcctattg taaaatacaa aattggtcct attaaactaa taaacagtac tacaataatc
    24541 catattgcct tatttccaat tttataattt ggatgtctca acacatgaac aagtgcagta
    24601 attataagta ttaaatctaa aataataaca ggaaccaaaa gtggtaagta ttccatcaaa
    24661 ttttccataa tcttattcct ccaataaaga taatttttct ataagaaatt tgtattcttt
    24721 gttttcactt aatacagaaa acattggatt atttttaata gcagcaacaa tacctgcttt
    24781 tacgattgta tcatcacgtg taatacctgt tccaatttca gaaatccatc tgtcaagttt
    24841 attaaaaaag tcatccccat gtattataat tgggtatata tcacgtgttg ctaaatctac
    24901 atattttcgt aatgatttaa tagctccttc attatcacca tgtattaaat taatttgtgc
    24961 ctgtgttaaa tatgaagaaa gcataatagc aggagataat gtatcaagct caaatatatc
    25021 tgaaattgct agaatacgtc tttctatttc cttcatttgt aatttatctg cattttgcaa
    25081 aatacccact aggttttgga ctaatgatat aaggttctga tatgcaccaa gttgaaatgt
    25141 ttctcttgct tcatccattt ggccattcat catttgcccc tgtgcaagaa gtatagattc
    25201 atttatcatg ggaaaattgc tgttttgcaa taaatcaatc acttgtatgg gttgatttaa
    25261 caatatataa caagttgcct ccatactttt tgcttgacgg caaatatcta tgtcattaca
    25321 agtttcctgt atacgaataa atatttctaa tgcttcacta attaatagtt cacgcttttt
    25381 ttcatctaca atatcatagt gattaactat taaaagaccc atccgaaaaa tcaaaggaaa
    25441 acatgaataa tattttttta tgatttctct tatttcatcc atgacttcat caaatggttt
    25501 aaccgtaaag tctttgcaca gtttattata cagtttatta atatcttcct tcatcatttg
    25561 aggttcataa catattaact catcaacggt aatgttgaaa tatgtcgcga gttgcggtaa
    25621 aaaggttatg tcaggatagc ttt
//
LOCUS       DAMJXI010000051        24833 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.053, whole genome shotgun sequence.
ACCESSION   DAMJXI010000051 DAMJXI010000000
VERSION     DAMJXI010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24833
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.053"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            129..1493
                     /locus_tag="PC465_002649"
     CDS             129..1493
                     /locus_tag="PC465_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HDF2649935.1"
                     /translation="MDIKELVKMQRKYYNTGKTRDISFRIEQLKKLKLVVSQNEEKIL
                     LALKKDLNKSDFEGFMTEVGMFYSELNFAIKNIRKWSKIKRVKSSMVNFPSISKIVPQ
                     PYGVTLIMSPWNYPFQLALIPLVWSLAAGNCVILKPSEYSVSTSSVVKDIVEDTFSKE
                     YVAVVQGSQEECEKLLLERFDYIFFTGSTNVGKIIMKSASEHLTPITLELGGKSPCII
                     LKDANIDLTAKRLTWGKLINAGQTCVAPDYVLVHEDRKNELIEKIKYYTNKYFGDNAC
                     NNEQFPKIINQKHFNRILSLIDKDKIVYGGNYNKETLKIEPTIVDNVNWDDNIMKEEI
                     FGPIFPILTYKDLDEVIQKIIQMPNPLALYIFTKNKYLENKLLEMIPAGGCCINDTVT
                     HIATNYLPFGGIGESGMGSYHGKAGFDTFTHYKSVLKKLNLDVPIRYAPYDNKLIKVL
                     KKIM"
     gene            1632..2798
                     /locus_tag="PC465_002650"
     CDS             1632..2798
                     /locus_tag="PC465_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF2649936.1"
                     /translation="MKINWNTKYTTIAIYTFIIAASSIIFYLVSSQIDVFSNNLDAIF
                     TTLQPFIIGFAIAYLLNFILKFYEDRIFIKSEKLKKLKQSSKRGLGLLLTYATATLIL
                     YLFMHFVLPQVIESIVGLANDIPMYVNNATKLIDKLMTDLNLDEQYFNLAVDKWNEFV
                     TYIIKFVTDLIPILGSMLKNVASSIWNIVLGLIVSVYLLIDKEKFYGLSKKITYAVFT
                     EKQAARILELTHRSNYTFGRFLGGKILDSFIIGILTFVILTLVKMPYTLLISVIIGIT
                     NIIPFFGPLFGAIPSTLIVMFVSPIKAFWLLLIILIIQQIDGNIIGPKILGDSIGISA
                     FWILFSLLVAGKLLGFIGMVIGVPMFAVIYSIIKDIVESKLDKKGLPTDTSDYM"
     gene            2915..3697
                     /locus_tag="PC465_002651"
     CDS             2915..3697
                     /locus_tag="PC465_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HDF2649937.1"
                     /translation="MAFIECKFKSKYTGGETDIIVILPVANGKELFSGKEIYDFEGKF
                     KTLYLFHGLEDDQSSWIRYTNVEHYAKNKNIALVIPRVETSFYTDMAYGHQYFTFVSE
                     ELPKFVRAIFPLSDKREDNFVAGMSMGGYGALKLALSKPKEFSAVASFSGSPDMIHEL
                     ENQQIETNADILFHDFGRPEDARNSENDLLYILKNLKERNEDIPKIYQFCGDRDFLYK
                     NNQMFKKYADSLGVDVEYEECVGGHEWRLWNLWIKKFIDIIG"
     gene            complement(3816..4469)
                     /locus_tag="PC465_002652"
     CDS             complement(3816..4469)
                     /locus_tag="PC465_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2649938.1"
                     /translation="MSKSEKGKETKASIISAARELFFEQGYHKTTTRQIAERANINLG
                     LISYYFSSKSEIGAIIYEDIRNEMQSLIYNYHEEGTMMMFFLAMNADLCFLLKNEAYR
                     NFYLDIAYEEAILSYQRSVTEMVMKRYVNDKESIEHDELILSCIGILAMKPEIIRVYT
                     SHKYDISSQAVIKHFTKQFLINLGHSTDLCEEILEELSKYYIDIVDNFTPIITRVRT"
     gene            complement(4493..5857)
                     /locus_tag="PC465_002653"
     CDS             complement(4493..5857)
                     /locus_tag="PC465_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HDF2649939.1"
                     /translation="MLLLIVTCAIYIWIGFYFSKKVKTASDFLIAGRNLPLPILAATI
                     AATSFGGGCLVGGVQWGAERGLWVGMYSTIGAALACFINAFFAGKLRSLSCDITPADY
                     IETRYGHSIFLRAYQSLVTPISILAIMGSQLISFGSVSTAFGIPYDIAVIIGVIVIII
                     YTYTSGMWGVAVSAFIQLAICIVFLPIVAYISLKLVGDNPLLMLQSMVKEPFFPGNKS
                     ISDFMYTVLPLVLGSIFSYESFLRYQCADNAKNAVKSSVIAGFILLFLAFPIGIIGAI
                     GGSLFPNISSVQVLPQMISTTLPPLISVLFLAAILAAIMSTADSLMTSMSAIISRDIY
                     NKLLHPNIEFNDLKNTLKYSQIASALTAIIGAIIALKFDSLLELLFWPAPLCTGVIFA
                     PFVIGLCWKGATKKGAIYAVIVSVILALLNMIGILTVFDRILVPIIGGSITIFIVSKF
                     SKKD"
     gene            6515..7945
                     /locus_tag="PC465_002654"
     CDS             6515..7945
                     /locus_tag="PC465_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2649940.1"
                     /translation="MSSQESKPKGNLISNFRDDMRDPKKRAIYTYSSSINLAYNFIGY
                     FVSTVTNIFLTDVAKLGVIMAGGMQIIQSFIKIAVAPITGTVFDKQPFKKGKYYPWLR
                     YAPAALALTYGIFFIVPLMKISPALLLPLMTALLLIASCAQQVVFTIIYAIYPVVAKT
                     PRDRVIGSTTTNIFKEVGKFLVGFSYPLLLVLFADVLGGEGMGYLGTYLFFAAGCLLV
                     FWFSSTEIIKSGAEEEVLQKEEKPKIKASEMAKALFTNVPLMMAFCLEFLICIRSIGL
                     GPLAPYYFKYVIEDERGLAVFLSIMPLVSVAFMFFAPVFIKICREQKLASIISFSICA
                     LCHLLVAWTPWGKTTLGVTMLLAIGGGFSNVVSIINLNFFAGSCDYGHWKSGKDLPGL
                     SMSLYPVAIQVGVLLATTIRTVLMNSMGYQADMVVTEAVKSGFINMISYSMAIPLIIA
                     VVIAILYPVSDKKLNQIREELNQRNA"
     gene            8048..9151
                     /locus_tag="PC465_002655"
     CDS             8048..9151
                     /locus_tag="PC465_002655"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HDF2649941.1"
                     /translation="MIEKLLRNTVKELHQYVPGEPIEKVKEKYGVKEIIKLASNENPL
                     GPSPKAIEAMIEMLKQGQLYPEPEANELRRKLAEKLDLKPENFIVANGADNVITLIGE
                     AFINRGDEVIYCNPTFPSYRTATIKNEGIPVEVPLTEDYKYDLQGILDKITDKTKLIC
                     VCNPNNPTGTIVDDKELEEFLKKVPENIITILDEAYIEFLTVPNYVDGLKYVRENYNV
                     IVTRTFSKIYGLAGLRVGYGIAKDEIIRTLFTVKEPFSANRVAISGATAALDDEEFIK
                     ETYELNRVGMAYFKEEFTKMGFDVVDSQSNFLYVDMKTDIPKLFEDLKKRGFVIRPSA
                     THARVSIGTMEENKKFVAVLKEILNIKGEPSIG"
     gene            9166..9402
                     /locus_tag="PC465_002656"
     CDS             9166..9402
                     /locus_tag="PC465_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2649942.1"
                     /translation="MKRGVDMNLKINAERCKSCEYCVISCKKGALKISSKINKEGYAH
                     VEVDESKCILCGICYQVCPDNVFEIIKEEACQEA"
     gene            9419..10468
                     /gene="vorB"
                     /locus_tag="PC465_002657"
     CDS             9419..10468
                     /gene="vorB"
                     /locus_tag="PC465_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HDF2649943.1"
                     /translation="MKKMWKGNHAIAEAALRGGCEFYAGYPITPQTEVMEFLSHRMSE
                     LGRTFIQSENEMAAIYMVYGAYASGMRSMTSSSGPGISLKQEGISYLCANHYPCVIVN
                     VQRWGPGLGSLDSAQTDYLRDTRGGGNGDYHLIVYAPNSIQETVDLMYNSFDVAEKYR
                     VPVEILTEAALGQMMEPVEFPEFKKREGDLGWTYDGSNRDHAKVADNQKPTFCMEKRM
                     RITENEQQWEDYQVEDAEYVFVAFGIPSRTTMNAVRRLREQGEKVGIIRPITVWPFPY
                     KAFEKVSKDVKGFISVESTDTGQLVEDVALASKKVCKENVPVYGLFSGNHIPKTLQVM
                     DTYSKIKSGEIKEVF"
     gene            10470..11210
                     /locus_tag="PC465_002658"
     CDS             10470..11210
                     /locus_tag="PC465_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HDF2649944.1"
                     /translation="MATEKLTPSVVSIPNKFCPGCGHGIVNRIIAEVIEEHGYEKNHV
                     LTLGVGCVCNMNFSWNGDKMQTAHGRASSTAIGVKVALPDTLVMTYQGDGDAYVIGLS
                     ETLNTAYRNHNVTVFVINNNNFAMTGGQMSWTTMPGQVTTTSVNGRDIKTTGSPLKVP
                     EMVANFFDVAYVARGSVHSPKEIINLKKYIKNAIEAQLNGEGYSLVEILAPCPTNWGV
                     SLEKSIKWMEEEIVPYYALGEFKQRDGE"
     gene            11213..11752
                     /locus_tag="PC465_002659"
     CDS             11213..11752
                     /locus_tag="PC465_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HDF2649945.1"
                     /translation="MEKELVFAGFGGQGVLTLGLIVAESALELGKQVTWMPAYGPTMR
                     GGKAYSVVKFSDESIGGPDMEEIDVLVAMNKPSLDYINLVKEGGTVVINTSAIDENVT
                     LREDISVVKINCQELAQKVNNPKAANIVVLGALIAKTGLFEKELALKTMCDFFEEKGK
                     GKFNVQNEAAFMEGYNNAI"
     gene            11876..13975
                     /locus_tag="PC465_002660"
     CDS             11876..13975
                     /locus_tag="PC465_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HDF2649946.1"
                     /translation="MSLEKLIRPKSIAIVGVTDKLGFGRSAALSIVKSKETDRVYYVN
                     PKREELFGRKCYKTIQEVPEVVDCVVVCTPRNVVPSVLKDSGELGTKAVVVYASGFAE
                     EGTEEGTDLENQLIEISNTYDMKILGPNCMGLLNCIDKVNLWAGGSKWDLDTKKPGIG
                     IVGQSGFITAEIVSSDYFNISYGFSTGNGNIVTLEDAVDFLVDDDYASVIAIYLEGLK
                     NPQKFIDALKRAAQKRKPVIILKSGRSEKGAISAASHTGNLAGSSKAFESIFEKYGVI
                     SVENLEQFMCLAQAFSVLDGNLPANSNFAAINFSGGENTICADLAEENGVELAEISSE
                     TKEEMKKYLPGFATPKNPLDATTALFHEKDMIVGLLHTFEKDDSVGFTMVGANIRDEE
                     NEMHETLCKAVSEAREQGLKKPVFAVPTLEGNRYLDYRTRLEDNQVPIMSSVGTTFTC
                     FNKMAKFIDYDYSKRTLEFKAVKKRESNNVVALSELDSKIEMKKYGVPVPGQGNAKSI
                     DELDEILKYIKYPVVLKINSSEILHKSDVGGVKIGIKNRDEAVDAYNEILTNVKKAKP
                     DANIDGILVQEMVESGIEIIIGITNDDQFGPMLLVGLGGVFVEVFKDTTLYPLPINHD
                     EAIMMLKKLKSFKLLNGYRGSEPCDIDALADMMVKLGKYAYENKDEVKEIDLNPVFVY
                     PKGKGVCAVDALIVKYK"
     gene            complement(14242..14757)
                     /locus_tag="PC465_002661"
     CDS             complement(14242..14757)
                     /locus_tag="PC465_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HDF2649947.1"
                     /translation="MISAKMEKLLNEQINHELYSAYLYLSMSSYLEAEGLKGFSNWFY
                     VQYKEETDHAMFFYKYLHNVGGKVQLDAIPMPDSDFTSAMDILERTLAHEKKVTALIN
                     NLASVANSESDFRTSQFLLWFISEQAEEETNCEDNIKRVKLAGEGGLFFVDQEFANRT
                     YAAPTNPPVTI"
     gene            complement(14849..16060)
                     /locus_tag="PC465_002662"
     CDS             complement(14849..16060)
                     /locus_tag="PC465_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HDF2649948.1"
                     /translation="MSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKM
                     TLSNLVTELINENMIREIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVII
                     SDLKGNIVKQLSETYPKCLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDIN
                     GTILNPPDFGNVSNLNIVDFIKEMSDLPIFLINDANSGALAEKMYGLGKNISNYIYLH
                     IMNGIGAGLVLENKLHTGNLGQSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKR
                     IESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFCTYVSYALVNTLTLID
                     CSSIIIGYDFNIPGTFIENTLLKKLTASASFSKYKKISVRHSNFGANAPLIGSIAIVS
                     YNFFNGSINFY"
     gene            16736..18178
                     /locus_tag="PC465_002663"
     CDS             16736..18178
                     /locus_tag="PC465_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF2649949.1"
                     /translation="MRTIRRVLALGLTLAIFLINVPNVDALTSDTIKGNNIYETAGLI
                     ADKKSYDTAIMVNMDNSIADGLSASGLAGAVDAPILLAQKNKIPNETKQRLKNVKKIY
                     IIGKELSISKSVETELKNTGAQVTRLGGDDRIKTSYSVAKEVNGIKKVDEVILTNAYK
                     GEADTISAAPVSVRDIAPIVLTDGKSVPFSTSNVKTYAVGGSISMSTSLVNKTNAKRL
                     GGSDRYDTNKKVIKEFYPDASEFYLSDGYDLVNALTGSTIAKENPIVLVSESSDKSIL
                     AGADKITRLGSISDSVYNKCVSAAQNNGDSSTKGESPMKNETSILGQPTASLEACLKW
                     AKSKKANDLFIELIPILYDTAVQEGVNPVLAVAQSAKETGFCNFGGVLDASFKNPCGL
                     KTSVGGSDTDKNAHSRFDTWEEGILAQIQHLCLYAGQDGYPLSNPVDPRHEKSLFGKA
                     KTVESLSNNWAGGQYGQDLVRMMGEIEATK"
     gene            18220..18573
                     /locus_tag="PC465_002664"
     CDS             18220..18573
                     /locus_tag="PC465_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649950.1"
                     /translation="MKKSNIFSIIFPTVIMVLMFLTFATDIFNIPDIQSKSIFVVGMV
                     LIFPISFLIQGIICVLNKTNWILSLIVSLVTYIVLMYIFLNDSAYIYVLLYTAFYMIG
                     HITAKLYYKIKTFKN"
     gene            18764..19585
                     /locus_tag="PC465_002665"
     CDS             18764..19585
                     /locus_tag="PC465_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HDF2649951.1"
                     /translation="MNLIDNHIHTNFSSDGKDSMEDTIKKAISIGVRYLTFTDHLEHD
                     EDRGFCINYNDYVPVFNKFKEKYKKDIELLLGVEVGYRKHLKNEIEEIINSNPFDFVL
                     CSTHTIDNVPVPSKAYFKGLSKEDAYYKYFNSILETNREFGDYNIYGHLDYISRYGIY
                     SDNRVIYNDFKDVIDEVLKSIINNGSGIELNTSGYRYGLNAIHPNEDILKRYKELGGF
                     IVTVGSDSHRVEDICKDFDVAYDMLKYLDFKYVSLFKERETYFVNIEKVKSNNIA"
     gene            19843..21726
                     /locus_tag="PC465_002666"
     CDS             19843..21726
                     /locus_tag="PC465_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HDF2649952.1"
                     /translation="MSNKNKENITLSNQIKGTIQNSLTKEAILHIPMSNYAYGYDRET
                     LHIRLRTKKNEAKRVILRIGDQYVWDKGGAGGGNLNASGVGWSGGTNIVMSKEVETEL
                     FDYWIAKCKPLNKRSRYGFIIEGQEEKLLFTEKRIIELGNENDEKELCEIGNFFGYPY
                     LNYIDIPKVPNWVKDTVWYQIFPDRFANGDPSINPEGVDKWGAIPTRDNFTGGDLQGV
                     IEHLDYLSDLGINGIYFCPITIGKTNHRYDTVDYMEVDPTLGDKETLKKLIEEAHKRN
                     IKIMLDAVFNHIGYYSKQWQDVVQNKENSRYKNWFYIKDMSKIDTPIEQIDEKNIPYE
                     TFGCEKYMPKLNTENSEVIKYLLDVGKYWIQEFDIDAWRLDVSNEVDHVFWRKFREEV
                     KKVKPDIYILGEIWHGSLPWLMGDQFDSVMNYLMSEAMKKFFCTDEINAEEFKYMIND
                     VMVSYPIQVSEVIFNLLGSHDTTRILTYANGNIDRFKLAYMFMFVQTGCPCIYYGDEI
                     GMEGELSSISEGQRKCMEWNEEKWNKDIFDFMKKIIRLRKENKELRSISNEWVLADKE
                     NGTIILKKESISIIINNSSKNIILTLPDYLANKKVKDLYEEEIVDLKEELMLEKYKFI
                     ILK"
     gene            21951..22631
                     /gene="pgmB"
                     /locus_tag="PC465_002667"
     CDS             21951..22631
                     /gene="pgmB"
                     /locus_tag="PC465_002667"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDF2649953.1"
                     /translation="MIEAFIFDLDGVITDTAYYHYMAWRKLAHKVGIDIDTKFNESLK
                     GISRMESLDRILEFGNKKYSFSEEEKVRMAEEKNNYYVSLIDEITSNDILPGIESLLI
                     DVKSNNIKIGLSSASKNAINVLNHLGISDKFDFIADAGKCKNNKPHPEIFLMSAKGLN
                     VNPQNCIGIEDASAGIDAINSANMFSVGVGNYENLKKANLVVDSTNQLKFEYIQEKYN
                     EYIVRRII"
     gene            22628..>24833
                     /locus_tag="PC465_002668"
     CDS             22628..>24833
                     /locus_tag="PC465_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HDF2649954.1"
                     /translation="MKCLFSNVDEWKIIQDKIEIKENRLAESIMSIGNGYMGMRGNYE
                     ENYSGDTHKGSYIAGVWFPDKTRVGWWKNGYPEYFGKIPNSVNYIGVRIFIDDVELDL
                     AKCKVEDFYRELDMKNGILNRRFIVNINDKKFEVRVARFLSISVKELAVIKYSIKSLN
                     SNTKIKFVPYLDSNIKNEDSNYDEKFWNGISSSSLEYKGSILSRTKENAFNTPVFTVG
                     SMMYIKTNGDVEAVSHESDYNYCENSITMDVLKNEVASIEKYVSITSTRDYKESELLR
                     KCEDILNRELSKSYDDILNEHTKLWNKRWESADVKINGDKSSQQGIRYNLFQLFSTYY
                     GEDSRLNIGPKGFTGEKYGGATYWDTEAFCVPVYLGVADKEVTRNLLEYRYNQLEQAK
                     DNAKKLGLKGALYPMVTFDGVECHNEWEITFEEIHRNGSIVYAIYNYTNYTGDYKYIK
                     EKGIDVIIEIARFWASRVHLSTKKDLYMIHGVTGPNEYENNINNNWYTNYIAKWCLDY
                     AVENILRLEKECNECIDRNNVTREEVEFWKIISNKMYLPYDEELQIIIQNDNFLDKEF
                     VEVKDLPKENFPLNQNWSWDKILRSCFIKQADVLQGIYYFGNRFTKEEKKRNFDFYEK
                     YTVHESSLSSSIYSIIASEIDNLEKAYELYSRTARLDLDNYNNDTNDGLHITSMSGSW
                     LSIVHGFAGMRTWNETLSFDPKLPKEWKNYSFNINYRDNIINVDVCSDLIKIE"
BASE COUNT         9598 a         2794 c         4331 g         8110 t
ORIGIN      
        1 tttttttatt ggaagattta tgttatattg agatgaattt attatgatat aaaaaataat
       61 gttaggataa atttaaatct ttttctaaaa atgtattaat ataattctta aagaaaggat
      121 ttttaacaat ggatataaaa gagttggtta aaatgcaaag aaaatattat aatacaggta
      181 aaacaagaga tatatcgttt cgtatagaac agttgaagaa acttaagtta gttgtatcac
      241 aaaatgaaga aaaaatactt ttagcactaa agaaagattt aaataaatcg gattttgaag
      301 gttttatgac agaggtaggc atgttttata gtgaattaaa ctttgctata aagaatataa
      361 gaaaatggag caaaataaaa agagttaaat caagtatggt taattttcca tctatatcca
      421 aaattgttcc acaaccttat ggtgttactc tcataatgtc accttggaat tatccatttc
      481 aattagcact tataccatta gtttggtcat tagcagcagg gaattgtgtt atattaaaac
      541 cttctgaata ttctgtgtca acatctagtg tagttaaaga catagttgaa gatacttttt
      601 caaaagaata tgttgcagtt gttcaaggaa gtcaagaaga atgtgaaaag ttactattgg
      661 aaagatttga ttatatattt tttacaggaa gtactaatgt tggtaaaata atcatgaaat
      721 cagcatcaga gcatttaact cctattactt tagaacttgg aggaaaaagt ccttgtatca
      781 ttttaaaaga tgctaatata gaccttactg ccaaaagact tacttgggga aaactaataa
      841 atgcaggaca aacctgcgtg gctccagatt atgttttagt gcatgaagat agaaaaaatg
      901 agttaataga gaaaataaaa tattatacta ataagtattt tggggataat gcatgtaata
      961 atgagcaatt tcctaaaatc ataaatcaga aacattttaa tcggatatta tctcttattg
     1021 ataaagataa gatagtctat ggtggaaatt ataataagga gacattaaag atagagccaa
     1081 ctatagtaga caatgttaat tgggatgata atataatgaa ggaagaaata tttgggccta
     1141 tatttcccat tttaacatat aaagatttag atgaagtaat acaaaaaatt atacaaatgc
     1201 caaatccatt ggcactttat atttttacaa aaaataagta cctagaaaat aaacttttag
     1261 aaatgattcc agcaggagga tgttgtatca atgatacagt tactcatata gctacgaatt
     1321 acttaccttt tggtggtatt ggtgaaagtg gtatgggctc atatcatgga aaagctggat
     1381 tcgatacatt tactcattat aagagtgtgt taaaaaaatt aaatttggat gtccctatta
     1441 gatatgctcc atacgataat aaattaatta aggttcttaa aaagataatg taggttatat
     1501 tgtagaataa taaatataaa taaaattgag tatttgtatt ctgaatatat tttattttta
     1561 atttggtata tttgttataa aagtggtgat tttgtgataa aatttaatta tatagaaata
     1621 aggaggaaaa aatgaaaatt aattggaata caaaatacac aacaatagca atttatacat
     1681 ttataatagc tgctagtagt attatatttt atctagtatc atcacaaatt gatgtatttt
     1741 ctaataattt agatgctata tttacaacat tacaaccttt tataatagga tttgctattg
     1801 catatcttct taattttatt ttaaagtttt atgaagacag aatttttata aaaagtgaga
     1861 aattaaaaaa actaaaacaa agttcaaaaa gaggcttggg tcttttatta acatatgcaa
     1921 cagctacatt gatactttac ttatttatgc atttcgtatt gccacaagta attgagagta
     1981 ttgttggact agcaaatgat atacctatgt atgtaaacaa tgcaactaag cttattgata
     2041 aattaatgac tgatttaaat cttgatgagc aatactttaa tttggcagtt gataagtgga
     2101 atgagtttgt tacatatatt ataaagtttg taacagattt aatcccaata ttaggaagta
     2161 tgttaaagaa tgtagcctct agtatatgga atattgtact aggattaatt gtttcagtat
     2221 acttattaat tgataaagaa aaattctatg gattaagcaa aaaaataact tatgcagtat
     2281 ttacagaaaa acaagctgcc agaattttag aattaactca tagaagtaac tatacatttg
     2341 gaagattttt aggtggcaaa atattagatt cattcattat aggtattcta acatttgtaa
     2401 tacttacatt agttaaaatg ccatatacat tattaatatc agttataatt ggtattacaa
     2461 atattatccc tttctttgga cctttatttg gagctatacc atctacgcta atagtgatgt
     2521 ttgtatctcc tataaaagct ttctggttat tgttaattat attaataata caacagatag
     2581 atggaaatat tataggacct aaaatacttg gagattcaat tggtatatct gcattttgga
     2641 ttttgttctc cttattggtt gcaggaaaat tattaggttt tattggaatg gttataggag
     2701 ttccaatgtt tgcagtaatt tattctataa ttaaggatat tgttgaaagt aaattggaca
     2761 aaaagggatt accgacagat acttccgatt atatgtagct aaaaaatatt atgtataatt
     2821 aaaaatatat aaattaagca atatttaaag cactgagaaa gttaaactct tggtgctttt
     2881 tagatataaa attattatag aagaggtgtt ttttgtggca tttatagaat gtaaatttaa
     2941 atctaaatat actggaggag aaactgatat aattgtaatt ttgcctgtag caaatggaaa
     3001 agaacttttt agtggtaaag agatatatga ttttgaaggt aaatttaaaa cattatactt
     3061 atttcatggt ttagaagatg accaaagctc atggattaga tatactaatg tagagcatta
     3121 tgctaaaaat aaaaatatag ccctagtaat accaagagta gaaactagtt tttatactga
     3181 tatggcgtat ggacaccaat attttacttt tgtaagcgag gaattaccta aatttgttag
     3241 agctatattt cctttatcag ataaaaggga agataacttt gtagctggta tgtctatggg
     3301 gggatatgga gctttaaaat tagcgctttc aaaaccaaaa gagttttcgg cagttgcaag
     3361 tttttctggt tcgcctgata tgattcatga gttagaaaat caacaaatag aaaccaatgc
     3421 agacattcta tttcacgatt ttggtagacc agaagacgct agaaatagtg agaatgattt
     3481 actttacata cttaagaacc ttaaagaaag aaatgaagat attcctaaaa tttatcaatt
     3541 ttgtggtgat agagattttt tatataaaaa taatcagatg tttaaaaaat atgcagattc
     3601 tctgggtgta gatgttgaat atgaagagtg tgtagggggg catgaatggc gtctttggaa
     3661 tttatggata aagaaattta tagatataat tggatagtac acttatggta ttaacaggta
     3721 tactataaaa tatctttaaa tatgataaag actgaaatcc taaaatcaaa ttatgatttt
     3781 aaaatttcag tctctaagaa tttaataaaa ttttattaag ttcttacacg agttattatt
     3841 ggagtaaaat tgtcaactat atctatatag tatttactca attcctctaa aatctcttcg
     3901 cataaatccg tactatgacc aagattaata agaaactgtt ttgtaaaatg ctttattaca
     3961 gcttgagaag atatatcgta cttgtgtgaa gtataaactc taattatttc aggtttcata
     4021 gcaagtatac caatacaaga aagtattaat tcatcatgtt ctatagattc tttatcatta
     4081 acatatcttt tcatgaccat ttcggttaca cttctttgat agcttaaaat agcttcttca
     4141 taagctatat ccaaataaaa atttctatat gcttcgtttt ttagaaggaa acaaaggtca
     4201 gcattcatag caagaaagaa catcatcata gtaccttctt catggtagtt atagattaaa
     4261 gactgcattt catttcttat atcttcatat attatagctc ctatttcgct tttacttgag
     4321 aagtaatagc ttattagacc taaatttata ttagctcttt ctgcaatttg cctagttgtt
     4381 gtcttatgat aaccttgctc aaaaaataat tctctagcag cacttataat actagctttt
     4441 gtttctttgc ccttttctga ttttgacata tttactgtgt atacctctct tttcaatctt
     4501 tttttgaaaa tttgctaact ataaatattg taatagaacc acctattata ggaaccaaaa
     4561 ttctgtcaaa tacagtaaga ataccaatca tatttaataa tgccaatata acacttacta
     4621 taacagcata gatagctcct ttttttgtag cacctttcca gcaaagacca attacaaatg
     4681 gtgcaaatat tacacctgta cataatggag ctggccaaaa caataattct aataaactat
     4741 caaatttaag tgctatgatt gcacctatta tagctgtcaa agctgatgca atttgagaat
     4801 actttagagt attttttaaa tcattaaatt ctatattagg atgtaataat ttgttataaa
     4861 tatctcttga tataatagca ctcattgagg tcattaatga atcggcagta gacattatgg
     4921 cagccaatat agcagctaag aataatacag atattaaagg tggtaaagta gtcgatatca
     4981 tttgaggtaa aacctgaaca gatgatatat ttggaaataa actaccacca atagctccaa
     5041 ttattcctat agggaaagca agaaataata gtataaatcc tgcaattaca ctacttttaa
     5101 ctgcattttt agcattatca gcacattgat atcttaaaaa actttcataa gaaaatattg
     5161 agcctaaaac taatggtaaa actgtataca taaaatcact aatcgattta tttcctggaa
     5221 agaatggttc ttttaccatt gattgtaaca taagtaaagg gttgtcgcca actaatttta
     5281 agcttatata agctactatt ggcaaaaaca ctatacaaat agcaagttga ataaatgctg
     5341 atactgcaac tccccacatt cctgatgtat aagtatatat aatgataact ataactccta
     5401 taattacagc tatatcataa ggaataccaa atgcagtaga tacagaacca aaagaaatta
     5461 attgactacc cataatagct agtatagata ttggtgttac aagactttga taagctctta
     5521 aaaatatact atgaccatat ctagtttcaa tataatcagc aggtgttata tcacaagata
     5581 agcttcttaa ttttcctgcg aaaaatgcat ttataaagca agctaaagct gcacctatag
     5641 tagaatacat tccaacccaa agtcctcttt cagctcccca ttgaactcca ccaactaagc
     5701 accctcctcc aaaagatgta gcagcaatgg ttgcagctag tataggcaaa ggcagatttc
     5761 tacctgcgat taggaaatcg gatgctgttt taactttttt tgaaaaataa aaaccaatcc
     5821 atatgtatat tgcacacgta acaattaaaa gtaacatagt cttttctcct ttataaaata
     5881 ttttaataaa atatacaaaa tatatttaaa atatatttta tataaaagta gtacgatatt
     5941 tgttttattg gttttagatt aatatagcta taataattta tgatattaga tggaaattac
     6001 gtaaaaatag aaaattgaaa attctgaaat ttttgcatat tgatatttat ctcatagatt
     6061 cttttttgta attgtaacac gcttttattt ttaaatcaat agtacatgta taaaaataaa
     6121 aggaatttaa ataagaaaaa gatattttta atatctggat gtagtataga aatatcttga
     6181 ataaattatt cttgaataaa attataaaaa attaaaatca ctagaaatat gataaaataa
     6241 tttaaaatac gcatttcaat gacatttcaa aacaagaaaa taataaaaaa caaacctaaa
     6301 ttaagtctaa atagcttttt agttaatttt agtagtaaaa aataaaactt aaaaagtgtt
     6361 tgacaattat gaattttgag aatataatta aattaaaatt atacacatat aaaaatatac
     6421 tcctgaatca agaatgagat atttaagatt caaaatatat attattatac gtgaataata
     6481 aaaagtaaga aaattttata agggaggggt agatgtgagt agtcaagaaa gcaaaccaaa
     6541 aggaaatctt atatcaaatt ttagagatga tatgagagac cctaagaaaa gagcaatata
     6601 cacatattca agttctataa acttagcgta caattttata ggttactttg tatcaactgt
     6661 tacaaatatt tttttaactg atgtggcaaa acttggtgta attatggcag gtggtatgca
     6721 aattatacaa tctttcataa aaattgctgt agctcctata acaggtacag tatttgacaa
     6781 acaaccattc aaaaaaggaa agtattatcc atggcttaga tatgcaccag cagcgttagc
     6841 attaacatat ggaatatttt tcatagttcc attaatgaaa ataagtccag cattactttt
     6901 acctttgatg acagctttat tattaatagc atcttgtgct cagcaagtag ttttcactat
     6961 aatttatgct atttaccctg tagttgctaa gacacctaga gaccgagtta taggctcaac
     7021 tactacgaat atatttaaag aagttggtaa attcttagta ggtttttcat atccgttatt
     7081 attagtttta tttgcagatg tattaggtgg agaaggaatg ggttatttag gtacctactt
     7141 attctttgca gcaggatgcc ttttagtatt ttggttttct tcaacagaga taataaaatc
     7201 tggagcagaa gaagaagttc ttcaaaaaga agagaagcca aagattaaag caagtgaaat
     7261 ggcaaaagct ttattcacta atgtaccact tatgatggca ttttgtttag aatttcttat
     7321 atgtataaga tctataggat taggaccttt ggctccatat tattttaaat atgtaataga
     7381 agatgaacgt ggattagcag tatttttatc aatcatgcct ttggtaagtg tagcattcat
     7441 gttttttgca ccagtgttta taaaaatctg tagagagcaa aaactagctt caataatttc
     7501 tttttctata tgtgcactat gccacttatt ggttgcatgg actccttggg ggaaaactac
     7561 tttaggagta actatgttgt tggcaattgg tggaggtttt tcaaatgtag tatcaataat
     7621 aaatcttaat ttctttgccg gttcttgtga ttatgggcat tggaaatcag gaaaagactt
     7681 acctggctta agtatgtcac tatatccagt tgcaatacaa gtaggagtat tacttgcaac
     7741 tactataaga acagttttaa tgaactcaat gggatatcaa gctgatatgg tagtcacaga
     7801 agcagttaaa tcaggtttta taaatatgat ttcttattct atggcaatac ctttaataat
     7861 agctgttgtt atagcaatac tatatccagt aagtgacaag aaattaaacc aaataagaga
     7921 agagttaaat caaagaaatg cttagttaaa agaaagttaa gtagatggtt aatttaagct
     7981 attaaagtaa gtagacgcaa tagcgtttat ataaatgaaa atacatatac agagggggct
     8041 tttaaaaatg atagaaaaat tattgagaaa taccgtaaaa gaattacatc aatatgttcc
     8101 aggtgaacca atagaaaaag ttaaggaaaa atatggtgta aaagaaataa taaaattagc
     8161 ttcaaatgaa aatcctctag gaccatcacc aaaagcaata gaagctatga ttgaaatgtt
     8221 aaaacaaggt caactttatc cagagccaga agctaacgaa cttagaagaa aattagctga
     8281 aaagttagat ttaaaaccag aaaattttat tgttgctaat ggtgcagata acgttatcac
     8341 tctaataggt gaggctttta taaatagagg agatgaagtt atatattgta acccaacatt
     8401 tccatcatat agaactgcaa ctataaaaaa tgaagggata ccagtagaag tacctttaac
     8461 agaagattat aagtatgatt tacaaggtat attagataag attacagata aaacaaaatt
     8521 aatatgtgta tgtaacccta ataatccaac aggaacaatt gtggatgata aagagttaga
     8581 agaattttta aagaaagtcc ctgaaaatat tataactata ttggatgaag catatataga
     8641 atttttaaca gttcctaatt atgtggatgg acttaagtat gtaagggaaa attataacgt
     8701 tatagtaaca agaactttct ctaaaatata tggtcttgca gggcttagag taggatatgg
     8761 tattgctaaa gatgagataa taagaacttt atttacagta aaagagcctt tctctgcaaa
     8821 tcgtgttgct ataagtggag caacagcagc acttgatgat gaagagttta taaaagaaac
     8881 atatgaatta aatagagttg gaatggctta ctttaaagaa gagtttacaa aaatgggatt
     8941 tgatgttgta gattcacaat caaatttcct ttatgtagat atgaaaacag atatacctaa
     9001 gttatttgaa gacttgaaaa aaagagggtt tgtaataaga ccaagtgcta cacatgcacg
     9061 tgtaagtatt ggaactatgg aagaaaataa gaaatttgta gcagttttaa aggaaatatt
     9121 aaatattaaa ggagagccaa gtattggata atagatagaa atattatgaa acggggtgta
     9181 gatatgaact taaaaataaa cgcagagaga tgtaaaagtt gtgaatactg cgttatatct
     9241 tgtaaaaaag gagcattaaa aatatcaagt aagataaata aagaaggtta tgctcatgta
     9301 gaagttgatg agagtaaatg catactttgt ggaatttgct atcaggtgtg tccagataat
     9361 gtttttgaaa taattaaaga agaagcatgt caagaggctt agaaggagtt gggataatat
     9421 gaaaaagatg tggaagggga accacgccat tgcagaagca gccctaagag gaggttgtga
     9481 attttatgca ggatatccaa ttacaccaca aacagaggta atggaatttt tatcacatag
     9541 aatgtctgaa cttggaagaa cttttataca gtccgaaaat gagatggctg ctatatatat
     9601 ggtatatgga gcatatgcaa gtggaatgag gtctatgacg agttcttcag gaccaggaat
     9661 atctttaaaa caagaaggga tttcttactt atgtgcaaat cattaccctt gtgtaatcgt
     9721 aaatgtacag agatgggggc ctggtcttgg ctcattggac tcagcacaga cagactatct
     9781 aagagatact agagggggag gaaatggaga ttatcatttg atagtttatg caccaaacag
     9841 tattcaagag actgtagatt tgatgtataa ctcatttgat gtagcggaga agtacagagt
     9901 gcctgttgaa attttgacag aagcagcttt aggtcaaatg atggaaccag tagaatttcc
     9961 agagtttaag aagagagaag gagatttagg ttggacttat gatggaagta atagagacca
    10021 tgcaaaggtt gcagataacc aaaagccaac tttttgtatg gagaaacgta tgagaataac
    10081 tgaaaatgaa caacaatggg aagattatca agtagaagat gcagaatatg tgtttgtagc
    10141 gttcggtata ccatcaagaa caactatgaa tgctgttaga agacttagag aacaaggtga
    10201 aaaagttgga ataataagac caataacagt atggcctttc ccatataaag catttgaaaa
    10261 ggtaagtaaa gatgtaaaag gatttatctc agtagaatca acagacacag gtcaattagt
    10321 agaagatgtt gctttagcct caaagaaagt atgtaaagaa aatgtacctg tgtatggttt
    10381 atttagtgga aatcatatac caaaaacatt gcaagtaatg gacacttata gcaaaataaa
    10441 atctggcgaa atcaaggagg tgttctaata tggctacaga aaaattaaca cctagcgttg
    10501 tttcaatacc aaacaagttt tgcccaggtt gtggtcatgg aatagtaaat cgtataatag
    10561 cagaggtaat agaagaacat ggatatgaaa aaaatcatgt attaacatta ggagttggtt
    10621 gtgtctgcaa tatgaatttt agctggaatg gtgataagat gcaaactgca catggtagag
    10681 cttcatctac agctatagga gttaaagtag cacttccaga tacattagta atgacttacc
    10741 aaggtgatgg agatgcttat gttataggtc tttctgaaac tttaaataca gcatatagaa
    10801 atcataatgt gactgtattt gtaataaaca ataataattt tgcaatgact ggtggacaaa
    10861 tgtcatggac cactatgccg ggtcaagtca caacaacaag tgtaaatgga agagatataa
    10921 agactactgg tagtccactg aaagttcctg agatggtggc aaacttcttt gatgtagcgt
    10981 atgtagcaag aggttcagtt catagcccaa aggaaataat taatctaaaa aaatatataa
    11041 aaaatgcaat agaagctcaa ttaaatggag agggatattc cttagttgaa atattagcac
    11101 cttgcccaac taactggggt gtatcactag agaaatctat caaatggatg gaagaagaaa
    11161 tagtgccata ttatgctctt ggcgaattta agcaaaggga tggtgaatag ttatggaaaa
    11221 agagctagta tttgcagggt ttggtggtca aggagtttta actcttggtc tgattgtagc
    11281 tgagtcagca cttgaattgg ggaaacaagt aacttggatg cctgcatatg gtccaactat
    11341 gagaggtgga aaagcctata gtgtagtaaa gttttctgat gagagtatag gtgggcctga
    11401 tatggaagaa atagatgttt tagtagcaat gaataaacca tctttagatt atataaattt
    11461 agttaaagaa ggtggaacag tagttattaa tacatctgca atagatgaga atgtaacatt
    11521 aagagaagat ataagtgtag ttaaaataaa ttgtcaggaa ttagctcaaa aagtaaacaa
    11581 tccaaaagca gcaaatatag tagtacttgg agcattaatt gctaaaactg ggttatttga
    11641 aaaagaatta gctttaaaaa ctatgtgtga tttctttgag gaaaaaggaa aaggaaagtt
    11701 taatgttcaa aatgaagcag cattcatgga aggctataat aacgccattt gataaattac
    11761 ccttatctta agtgatttat ctcaagattt aataatcttt agtgccaaga gaaacttcat
    11821 cttgagataa aattcactta aaatcacaac tataaacata taggagcgtg aatttatgag
    11881 tttggaaaaa cttattagac caaaaagtat tgctatagta ggagtgactg ataaacttgg
    11941 ttttggaaga agtgcagcac ttagtatagt aaaaagtaag gaaacagata gagtatatta
    12001 tgttaatccc aaaagagaag aattgtttgg gagaaaatgt tataagacga tacaagaagt
    12061 tccagaagta gtagactgtg tagtagtatg tacgcctaga aatgtagttc catctgtatt
    12121 aaaagattct ggagagttag gaacaaaggc agtagtggta tatgctagtg gatttgcaga
    12181 ggaaggtaca gaggaaggta cagatttaga aaatcaactt atagaaatat caaatacata
    12241 cgatatgaaa atattgggtc caaactgcat ggggttgcta aattgtatag ataaggttaa
    12301 tctatgggca ggaggttcta aatgggattt agatactaaa aaacctggta taggaattgt
    12361 aggtcaaagt ggatttataa ctgctgaaat tgtttcaagt gattatttta atatatctta
    12421 tggtttttca acaggaaatg gaaatatagt tacactagaa gatgcagtag atttccttgt
    12481 agatgatgat tatgcatcag taatagcaat ttaccttgaa ggtttaaaaa atcctcaaaa
    12541 atttatagat gctttaaaaa gggcagcaca aaaaagaaag ccagtaataa tattgaaatc
    12601 aggaaggtca gaaaaaggtg ctatttctgc tgcttctcat acaggaaatt tagctggttc
    12661 gagtaaagct tttgaaagta tttttgaaaa atatggagta atttctgtgg aaaatttaga
    12721 acagtttatg tgtttagcac aagcttttag tgttttagat ggtaatttac ctgcaaattc
    12781 taattttgca gcaataaact tctcaggagg agaaaatact atttgtgcag atttagcaga
    12841 agaaaatggt gtagaacttg cagaaatatc ttctgaaact aaagaagaaa tgaaaaaata
    12901 tcttccagga tttgcaacac ctaaaaatcc actagatgct acaacagcat tattccatga
    12961 aaaggatatg atagtaggtt tattacatac ctttgaaaag gatgatagtg ttggatttac
    13021 tatggtaggt gcaaatataa gagatgaaga aaatgaaatg catgaaaccc tttgtaaagc
    13081 tgtaagtgaa gctagagaac aaggattgaa aaaacctgtg tttgcagttc ctacacttga
    13141 aggaaataga tatttagatt ataggactag attagaagat aatcaagtgc ctataatgtc
    13201 atcagttgga actacattta cttgttttaa taaaatggct aagtttatag attatgatta
    13261 ttcaaaaaga actttagaat ttaaagctgt taagaaaaga gagtcaaata atgtagtagc
    13321 attatcagaa ttagatagta agattgagat gaaaaaatat ggagtaccag ttccaggaca
    13381 aggtaatgca aaaagtattg atgaattaga tgaaatctta aaatatatta agtatcctgt
    13441 tgttttaaaa ataaattctt ctgaaatatt gcacaaatct gatgttggag gagttaaaat
    13501 aggaattaag aatagagatg aggcagtaga tgcatataat gagattttaa ctaatgtaaa
    13561 aaaagcaaaa ccagatgcta atattgatgg tatattagtt caagaaatgg tagaaagtgg
    13621 tatagaaatt attattggta taactaatga tgaccaattt ggaccaatgt tattagtcgg
    13681 tttaggagga gtatttgtag aggtatttaa agatactaca ttatatccat tacctataaa
    13741 tcatgatgaa gctattatga tgcttaaaaa actaaaatca tttaagcttt taaatggcta
    13801 tagaggaagt gagccttgcg atattgatgc tcttgcagat atgatggtca aattaggaaa
    13861 atatgcttat gaaaataagg atgaagtcaa ggaaatagac ttaaatccag tgtttgtata
    13921 tcctaaagga aaaggcgtat gtgcagtaga tgccttaata gttaaatata aatagtttat
    13981 aagttttggt attcaaccat aattaaagca ccgactgaaa atcacatttt gtaagttaga
    14041 tagtgtgatt ttcagtcacc ccaaatttaa tttaaaaata ttttaaaatg aaagtatagt
    14101 tttaagtttc attgtgaaat agcactgtat aaacaataaa atactacgta taaaacgaat
    14161 aataaaaggt gttttaatga taagaatcaa tcttgatttt cattaaaaca ccttctttat
    14221 tatattaaaa atttttaaac gttatattgt cacaggtggg tttgttggag ctgcatatgt
    14281 acgattagca aattcttggt caacaaagaa tagaccaccc tctccggcaa gtttaacacg
    14341 ttttatattg tcttcacaat ttgtctcttc ttctgcttgt tcagatataa accaaagtaa
    14401 gaattgagaa gttctaaagt ctgattcaga gtttgctaca gatgctaagt tgtttattaa
    14461 agctgtaacc tttttttcat gagctaacgt acgctcaaga atatccattg cagaagtaaa
    14521 gtctgaatct ggcattggga tagcatcaag ttgaaccttt cctcctacat tatgtaagta
    14581 tttgtaaaaa aacatagcgt ggtctgtctc ttctttatat tgaacataaa accaattaga
    14641 aaatccttta agtccttctg cttcaaggta agaagacata gaaagataaa gatacgcaga
    14701 atataattca tggttaatct gctcattaag taatttttcc attttagctg aaatcatttt
    14761 tatacctcca aattttaaat gctcttataa aatataataa tattaaatgg aaaaatattc
    14821 aataaaagtg tttaaatatt ttacatattt aataaaaatt tatactacca ttaaaaaaat
    14881 tataacttac aatggctata gagccaatta atggtgcatt tgctccaaaa tttgaatgcc
    14941 ttacacttat ttttttatat ttagaaaaac ttgctgaagc agtcaatttt tttaataatg
    15001 tattttctat aaatgtacca ggtatattaa agtcatagcc tattattata gaactacaat
    15061 caatcaatgt aagtgtatta actaatgcat atgatacgta tgtacaaaat tcatcaagca
    15121 aaaacatggc aagactatct ttattatttg cctcatctat taacttgact aaagaaaaat
    15181 ctttacagtt aattaatggg gagttaggat aaatatggct caatgattca attcttttaa
    15241 ttagattact gacacttgta taataatcta aacatccatt gttaccacaa ctgcacaatg
    15301 gtccactaaa attaattgat gtatgtccta tttctccact ttgtcctagg ttgccagtat
    15361 gaagtttatt ttctagaact agaccagctc caataccatt cattatgtgt aggtatatat
    15421 aatttgatat atttttacct aaaccataca ttttttctgc taatgcaccc gaattagcat
    15481 catttatcaa aaatattggc aaatcagaca tttcttttat aaaatctact atatttaggt
    15541 ttgatacatt tccaaaatct gggggattta gtatggtacc atttatatca tctactggac
    15601 ctattgaaga aataccaatt ccaattatat ctctcttgtt gattttcatt attttagtaa
    15661 acattctttt tattatatct tttaaaacat catttgatag acatttaggg taagtttcag
    15721 aaagttgttt tacaatatta ccttttaaat ctgaaataat taccttacat atatttcttc
    15781 ttattaggat tccacaaata caaggcgata tattagaaat atctaataaa atgggtttac
    15841 gacctgatga atgtgcattt aaagttgatg actctatttc cctaatcata ttttcattaa
    15901 taagttcagt aactagattt gataaagtca ttttagtaag tcctgtagac ttagctaaat
    15961 caactctgga cataggtgta tttgtagaaa gtaatttcaa tattattaac ttatttttaa
    16021 tttttacatc tttgatgtta gaaccttgtt tgttactcat cataaatctc cttaaataaa
    16081 gttaagtgtt ttatttattt tcaagtatac tatcacctta taatagagta acattttttt
    16141 acttgaaaat atcattaatt agaatatatc acattatata tcataaaata tataaaaaaa
    16201 tgttagaatt aaattaaaag tgaaaagtag attgatatat aaatagtaaa tacttaatta
    16261 aaaaaagata atgatagcaa taattattgt taccaagaat ctactacttc aagtgttacc
    16321 ttaggtattt aagttgatag tggtttgcac gtaataaact tgatgtaata tatattctta
    16381 ataatattga taaaagattt acttaaaaat aatatagatt atgtaaacat ataatctatt
    16441 tattgtatac aataaaattt cattttgtaa aacagtgaat taaatatgta atatagatat
    16501 cgatttttat tacaaattgt tactaaatat aggtacatta gaacaaaaat ctagtaaatt
    16561 gtaactaaaa tgtaaatttt tcctttaatc tatacaatat tatggaaact ttttgtaatt
    16621 tatgatataa taacaaatat ataattatta aattataata aatgactata gcgtagatgt
    16681 aatactatgt tatagtcatt tttgaattaa acttgatata tcaaggggga agaatatgag
    16741 aacaattaga agagttttag cattaggttt aacattagct atatttctaa taaatgtacc
    16801 taatgtagat gcattaacat cagatacaat taaaggtaac aatatatatg agacggctgg
    16861 attaatagca gataaaaaga gttatgatac agcaattatg gtaaatatgg ataattctat
    16921 agcagatggt ctttcagcaa gtggtcttgc aggtgctgtt gatgctccaa ttttgcttgc
    16981 acaaaaaaat aagataccaa atgaaacaaa acaaagatta aaaaatgtta aaaagatata
    17041 cataataggt aaagaattat caataagtaa gtcagtagaa actgaactaa aaaacacagg
    17101 ggcacaggta actagattgg gtggagatga cagaataaag actagttata gtgttgctaa
    17161 agaggtaaat ggtatcaaaa aagttgatga agtgatatta actaatgcat ataaaggaga
    17221 agcagataca ataagtgctg cacctgtatc agtaagagat atagctccta tagtacttac
    17281 agatggaaag agtgtgcctt tttcaacaag taatgtaaaa acatatgcag taggtgggag
    17341 tatatcaatg agcactagtt tagttaataa aactaatgct aaaagacttg gtggttcaga
    17401 tagatatgat acaaataaga aagttataaa agagttttat ccagatgcat cagaatttta
    17461 tttgagtgat ggatatgatt tagtaaatgc acttacaggt tctacaattg ctaaggaaaa
    17521 tccaattgta ttggtgtcag aaagtagtga taagtctata ttagcaggag cagataagat
    17581 tactagatta ggttcaataa gtgacagtgt gtataataag tgtgtttctg ctgcacaaaa
    17641 taatggcgat tcgtctacaa aaggtgagtc acctatgaaa aatgagacaa gcatattagg
    17701 tcagccaaca gctagtttag aagcgtgctt aaaatgggca aaatctaaaa aagctaatga
    17761 tttatttata gagttaatac caatattata tgatactgct gttcaggaag gtgttaatcc
    17821 tgttttggca gtagctcaat ctgcaaaaga aactggtttt tgtaattttg gtggagtatt
    17881 agatgcatca tttaagaatc cttgtggact taaaacttct gtaggtggtt ctgatactga
    17941 taagaatgcc cattcaagat ttgatacttg ggaagaagga atattagctc aaattcaaca
    18001 tttatgctta tatgcaggac aagatggtta cccactttca aatccagtag accctagaca
    18061 tgaaaaatct ttatttggta aggctaaaac agttgaaagt ttatctaata attgggctgg
    18121 aggtcaatat ggacaagatt tagtaagaat gatgggagaa attgaggcaa caaaataatt
    18181 gaagattatc aaatatccaa taaataagga ttgattatta tgaaaaagag taatattttt
    18241 agtatcatat ttcctacagt cataatggtg ctaatgtttt taacttttgc tacagatata
    18301 tttaatattc cagatattca atctaaaagt atttttgttg tgggaatggt tttgattttt
    18361 ccaatttctt ttttgataca agggataatt tgtgtattaa ataagactaa ttggatttta
    18421 tctcttattg tgtctttagt aacttatata gtattaatgt atatattttt aaatgattct
    18481 gcatatatat atgttttact ttatacagct ttttatatga ttggacatat aacagctaaa
    18541 ctctattaca aaattaagac ttttaaaaat taaattgaag tatataaaag taacattaag
    18601 agaagtatcc ttaatgattt tctaaaatca gaaataggtg cttctctttt ttgtaaaaat
    18661 aaaagtatgt aaataaaatt taaccattat aattttcttt taacaagtgt atacaataaa
    18721 cttgttgtat aattaagata gataaaataa agggagggat aatatgaatt taatagataa
    18781 tcatattcat actaattttt caagtgatgg aaaggattcc atggaagata caataaaaaa
    18841 agctataagt attggtgtta gatatttgac ttttacagac catttagaac atgatgaaga
    18901 tagaggattt tgcataaatt ataatgacta tgttccagta tttaataagt ttaaagaaaa
    18961 atataaaaag gacatagagt tattactagg tgttgaagtg ggttacagaa aacatctaaa
    19021 aaatgaaata gaagaaataa taaattctaa tccttttgat tttgtattgt gctcaactca
    19081 tacaattgac aatgtacctg ttccatcaaa ggcgtatttt aaaggtctta gcaaagaaga
    19141 tgcgtattat aaatatttta atagcatact tgaaactaat cgtgaatttg gagattacaa
    19201 tatatatggt catttggatt atatatctag gtatggaata tattcagata atagagttat
    19261 atacaatgac tttaaagatg ttattgatga ggtcttaaag tcaataatca ataatgggag
    19321 tggtatagag ctaaatactt ctggttatag atatggacta aatgctatac atccaaatga
    19381 agatattcta aaaagatata aagaacttgg aggatttata gttactgtag gttctgattc
    19441 tcatagggta gaagatatat gcaaagattt tgatgtggcc tatgatatgc ttaagtatct
    19501 tgactttaaa tatgtatctt tatttaaaga aagagaaact tattttgtaa atatagaaaa
    19561 agttaaatct aacaatatag cttagagtgt gttttgaagt aaattaatgg atagttaaaa
    19621 agttaatagt tataatattg tatcctctag aaaaatacta gaggttttta ttttgctaaa
    19681 ataactaaat agaattaaat ttaaatagta tagcttattt taaattgaat agtttattgt
    19741 tgatatattt tactattata tatttttatt gtgatataat agtaaaatat attaacctat
    19801 ctttagatta tataaattat tataaaggag ggaaatttta aaatgtctaa taaaaataaa
    19861 gaaaatataa ctttaagtaa tcaaatcaaa ggaacaattc aaaatagttt aacaaaagaa
    19921 gctatattac atataccaat gagcaattat gcctatggtt atgatagaga aacactacat
    19981 ataagactta gaactaaaaa aaatgaagcg aaaagagtaa ttttacgaat aggagaccaa
    20041 tatgtgtggg ataaaggagg tgcaggagga ggaaatttaa atgcatctgg agttggttgg
    20101 tctggtggaa caaatatagt aatgagtaaa gaagtagaaa ctgaattatt tgactattgg
    20161 atagctaagt gtaagccttt aaataaacgc tcacgatatg gctttataat agaaggtcaa
    20221 gaggaaaaac ttttatttac agaaaaaaga ataatagagt tgggaaatga aaatgatgaa
    20281 aaggaattat gtgaaatagg taattttttt ggatatccat atttaaatta tatagatata
    20341 cctaaagtgc caaattgggt gaaagatact gtttggtatc agatatttcc agatagattt
    20401 gcaaatggtg acccgtctat aaacccagaa ggagtagata aatggggagc tattccaacc
    20461 agagataatt ttacaggtgg agatttacaa ggtgtgatag aacacttaga ttatttgagt
    20521 gatttgggaa taaacggaat ttacttttgc cctattacaa ttggaaaaac caatcataga
    20581 tatgatacgg tagattatat ggaggtagac cctacattag gagataaaga gactttaaaa
    20641 aaactaatag aagaagcgca taagagaaat ataaaaataa tgttggatgc tgtttttaat
    20701 catataggat attattctaa acagtggcaa gatgtagttc aaaataagga aaattctcga
    20761 tataaaaact ggttttatat aaaagatatg agtaaaattg atactccaat agaacaaata
    20821 gatgaaaaaa atatacctta tgaaaccttt gggtgtgaaa aatatatgcc taaacttaat
    20881 acagaaaatt cagaagtaat aaaatattta ttggatgtag gcaagtactg gatacaggaa
    20941 tttgatatag atgcgtggag attagatgtt tcaaatgaag tagaccatgt tttttggaga
    21001 aagtttagag aagaagtcaa aaaagtaaaa ccagacattt atatattggg agaaatttgg
    21061 catggtagtt taccatggct aatgggtgac caatttgatt cagttatgaa ttacttgatg
    21121 tcagaagcca tgaaaaaatt cttttgtaca gatgagataa acgccgaaga atttaagtat
    21181 atgataaatg atgtaatggt aagttatcca atacaagtta gtgaagttat ttttaattta
    21241 cttggaagtc acgatactac aagaatattg acttatgcta atggaaatat tgatagattt
    21301 aaacttgcat atatgtttat gtttgtacaa acaggatgtc cttgtatata ctatggtgat
    21361 gaaatcggaa tggaaggaga attaagttca atatctgaag gtcaaagaaa atgtatggaa
    21421 tggaatgaag aaaaatggaa taaggatata tttgatttta tgaagaagat tattagactt
    21481 cgtaaagaaa ataaagaact taggtctata tcaaatgaat gggtgttagc agataaggaa
    21541 aatggaacga ttatattgaa aaaagaatct atttctataa taataaataa ttcatctaaa
    21601 aatataattt tgacgttacc agattattta gcaaataaaa aagtaaaaga tttatatgaa
    21661 gaagaaatag ttgatttaaa agaagaacta atgttagaga aatacaagtt cattatttta
    21721 aaataataca aaaaagtatt tattttagat ttcatgttaa attattatac agtttaaata
    21781 agtctttata aacgataaaa aaatatggtc tacaagtgag tgaattgaaa gtagatttta
    21841 aattaaagac tgagttagag tagataattt tataaataat atcttaaata caagatagaa
    21901 aataaattga ttattagtct aaaaatttct tgtagaaaga ggaaataaga atgattgaag
    21961 catttatatt tgatttagat ggtgtaatta cagatactgc atattatcac tatatggctt
    22021 ggagaaaact agcccataaa gttgggatag atatagacac aaaatttaat gaatctttaa
    22081 aaggcataag tagaatggag tcattggaca ggatattaga atttggaaat aagaaatatt
    22141 cattttcaga agaagaaaaa gtgagaatgg ctgaagaaaa aaataattac tatgtatcat
    22201 tgatagatga gataacttca aatgatattt tgccaggtat agaaagcttg ttaattgatg
    22261 taaaatctaa taatataaag ataggtctat cttctgcaag taagaatgca ataaatgtat
    22321 taaatcattt gggtataagt gacaaatttg attttatagc tgatgcagga aaatgtaaaa
    22381 acaataaacc acatccagag atatttctta tgtcagcgaa agggcttaat gtaaatccac
    22441 aaaattgcat agggatagag gatgcaagtg caggtataga cgctataaac tcagctaata
    22501 tgttttctgt tggtgttgga aattatgaaa acttaaaaaa agcaaattta gttgtagatt
    22561 caacaaatca attaaagttt gaatatatac aagaaaagta taatgagtat atagttagga
    22621 gaattatatg aaatgtttat ttagtaatgt agatgagtgg aagattatac aagataagat
    22681 tgaaatcaaa gaaaatagat tagcagagtc cataatgagt ataggcaatg gatatatggg
    22741 tatgagagga aactatgagg aaaattatag tggagataca cacaaggggt cttatatagc
    22801 tggagtatgg tttccagaca aaactcgtgt tggttggtgg aaaaatgggt atccagaata
    22861 ctttggtaaa attcctaatt cagtcaacta tataggtgta agaattttca tagatgatgt
    22921 agaattagat ttagcaaaat gtaaagtaga agatttttat agagaattag atatgaaaaa
    22981 tggtatttta aatcgtaggt ttattgtaaa tataaatgat aaaaaatttg aagttagggt
    23041 tgctaggttt ttaagtatat ctgttaagga acttgcagta attaaataca gtataaaatc
    23101 attaaattct aatactaaaa taaaatttgt accatattta gattcaaata taaaaaatga
    23161 agattcaaac tatgatgaaa agttttggaa tggaatttct tcaagttctt tagaatataa
    23221 aggtagtatt ctttctcgaa caaaggagaa tgcatttaat acaccagtat tcactgtggg
    23281 ttcaatgatg tatattaaga caaatggtga tgtagaagct gtatctcatg agagtgatta
    23341 taattactgt gaaaattcga taacaatgga tgttttaaaa aatgaggttg caagtataga
    23401 aaaatatgta tctataactt caactagaga ttataaggaa agtgagctat taagaaaatg
    23461 tgaagacatt ttaaatagag aactatctaa aagttatgat gatatattaa atgaacatac
    23521 aaagttgtgg aataaaagat gggaaagtgc agatgtaaaa ataaatggag ataaaagtag
    23581 ccaacaaggt ataagatata atttattcca actattttca acatattatg gagaagattc
    23641 gcgattaaat ataggtccaa aaggatttac tggtgaaaag tatggaggag ctacttattg
    23701 ggatacagaa gcgttttgtg ttccagtata tctaggtgta gcagataagg aggtaactag
    23761 aaatctttta gaatataggt acaatcagtt agaacaggca aaggataatg caaaaaaact
    23821 agggcttaaa ggtgctttat atccaatggt aacatttgat ggagtagaat gtcataatga
    23881 atgggagata acatttgagg aaatccaccg aaatggaagt atagtatatg caatatataa
    23941 ctatacaaat tatacaggtg actataaata tataaaagaa aaaggaatag atgtaataat
    24001 agaaatagct agattttggg caagtagagt tcatttgtct acaaaaaaag atttgtatat
    24061 gatacatgga gtaacaggtc caaacgagta tgaaaacaat atcaataata attggtatac
    24121 taattatata gctaaatggt gtttagatta tgctgtagaa aatatcttac gattagagaa
    24181 agagtgtaat gaatgtattg acagaaataa tgtgactagg gaagaagttg agttttggaa
    24241 aataatatca aataaaatgt atctaccgta tgatgaggaa ctacaaataa taattcaaaa
    24301 tgataatttt ttagataaag aatttgtaga agtaaaggat ttaccaaaag aaaattttcc
    24361 tcttaatcaa aattggtctt gggataagat tcttaggtcg tgttttataa aacaagcaga
    24421 tgtattacag ggaatttact attttggaaa tagatttact aaagaagaaa aaaagagaaa
    24481 ttttgacttc tatgaaaaat atactgtaca tgaatcttct ttatcttcta gtatttattc
    24541 tattattgcc tcagaaatag ataacctaga aaaggcttat gaattatatt caagaacagc
    24601 taggcttgat ttagataatt acaataatga tacaaatgat ggactgcaca taacttcaat
    24661 gtctggttca tggctttcca ttgtacatgg atttgcaggc atgagaacat ggaatgaaac
    24721 tctatctttt gaccctaagt tgccaaaaga gtggaaaaat tattctttca atataaatta
    24781 tagagataat attattaatg tagatgtatg tagtgattta attaaaatag aaa
//
LOCUS       DAMJXI010000052        24553 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.054, whole genome shotgun sequence.
ACCESSION   DAMJXI010000052 DAMJXI010000000
VERSION     DAMJXI010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24553
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.054"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(500..676)
                     /locus_tag="PC465_002669"
     CDS             complement(500..676)
                     /locus_tag="PC465_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649955.1"
                     /translation="MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVE
                     TCLHQVLLLVSRYN"
     gene            1251..2273
                     /locus_tag="PC465_002670"
     CDS             1251..2273
                     /locus_tag="PC465_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649956.1"
                     /translation="MVNWEIKKLAKSKSMFISLGILVLILMISIFIAPVLETESYYID
                     KEKGRIEDTRSGIDIGNEKFQNKINVLKQFSNQTDTGEFSKKIELMSKKKLDNLSVNE
                     YKDISFWKVFNYRVTNSLINVGMLIIISIIISNIYVDEVVTSVKDIILSSKEKKKALK
                     SKIFVALLVPLVIYSVYLMGIFIITCMQQGVPVNGDLESFRIVDNVVALKTNLSITKY
                     VILNIGIELLMFEGWAMIAIFGSFISKSSISSISFFIFIISITKIMSVIHILPKKLLS
                     VVSNVNYYDLIFGFNKIIGNYLGDIMIFKVNIDIVNIAIGLLMAILIGTMSLCFLVIK
                     SDYISR"
     gene            2287..3174
                     /locus_tag="PC465_002671"
     CDS             2287..3174
                     /locus_tag="PC465_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2649957.1"
                     /translation="MNKLEIENLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTL
                     MKQITTLIKPDEGQILYNGEDIFKMDADYRNILGYLPQEFGVYKNFTAKEFLQYIGAL
                     KGLRGKYLNSKIGELLDLVGLYDVRNKSIGKFSGGMKRRVGIAQVLLNDPKIIVLDEP
                     TAGLDPQERARFRNLIAKMSRDKIIILSTHIISDIESVAKETIMIKDGKLLMKGTHKD
                     ILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDINSIVLRIVSEDILSEDNIQPVQ
                     AKFEDVYMFYFDLEDAREV"
     gene            3180..3953
                     /locus_tag="PC465_002672"
     CDS             3180..3953
                     /locus_tag="PC465_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2649958.1"
                     /translation="MMYLVKAEMIKILKSKSVWIIWLFLIFFGFFLIRKFDVLDTYAD
                     IFYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKKGKKSVVLSKLVANGLIL
                     SIINISFILLVGIRGFSFFDFKNLNEPIHNLWYFGNSNLNLTVIQMYIIVILTTIFAS
                     FIFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQ
                     MVKYNVPSILIVFSIVISIILMIVLTKITYENFTSSKRF"
     gene            4065..4790
                     /locus_tag="PC465_002673"
     CDS             4065..4790
                     /locus_tag="PC465_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012450879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2649959.1"
                     /translation="MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFK
                     SINPDLIVLDIMLPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVT
                     KPFSPKEVAFRVKAHLRRLSYFSDAQNESKNLNNNEEKIISFGPYILNESRAELIKDG
                     KSIGLSAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLED
                     NPSKPEYILTIKGLGYKLAVKED"
     gene            4794..6197
                     /locus_tag="PC465_002674"
     CDS             4794..6197
                     /locus_tag="PC465_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2649960.1"
                     /translation="MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSG
                     NNPEEFARSFEKDLYEKDGEFKLSKIGAEKLEKSNSWIQVLNDLGEEVYGVNVPKDTP
                     KKYTPFQMVNNYKYIETKYVNFVLEKYLNKKHLNIIVGIPSRDISRIILTYSQNNIKK
                     TLNKVIIITLVIDSVVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYE
                     EVFKNINMLADTLRVNEVERKENEELREEWLANITHDIKTPLASIQGYAEIINDKDYE
                     FEEDEIQEYTEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKKINLVSLVRDIIIDI
                     LNDNRYKNRNIEFESNEDLIEVYVDSILFRRAITNLIFNSIVHNSEGTLISVEIVKKD
                     NIEIIIKDNGIGISKSDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYV
                     SSEIGIGTKIIIEIKQN"
     gene            6208..7032
                     /locus_tag="PC465_002675"
     CDS             6208..7032
                     /locus_tag="PC465_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraX"
                     /protein_id="HDF2649961.1"
                     /translation="MDFFKKGISGFTIKILALIFMTFDHIAAFMPQTMQIPIWFHWVG
                     RISAPLFIFMAVEGFYHTSNRKKYISRLYIWSVIMAIGNQIINNVFSHPEGAIIINNI
                     FSTLFLIAIYLQAIEFIKKFRKEKEIKYFIIGLLMIIIPIILGIFTVALLFKVTNRVI
                     ALFMILVPVPFLVEGGPIWIILGIIFYLCRGKKFSLSICYALMCIFIFTTMSNGDYSL
                     KNSILQNYQWMMIASLPLMLLYNGEKGKSMKYLFYLYYPIHVYILYILGIYLINGF"
     gene            complement(7357..7977)
                     /locus_tag="PC465_002676"
     CDS             complement(7357..7977)
                     /locus_tag="PC465_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2649962.1"
                     /translation="MKVLLINGSPNQYGCTYTALNEITKVLSKHDIKTEILYLGKETI
                     PGCISCASCFETGKCIRNDKVNELIEDLDNIDGIIIGSPVYFSSATGQLTSFLDRLFF
                     IAGSRMATKLGASVVSCRRGGASATFDQLNKYFSISNMPIVSSQYWNQVHGFTPEDVM
                     KDEEGLQTMRTLGENMAWLLKCISAGKKAGIKEPQYEETIMTNFIK"
     gene            8242..8574
                     /locus_tag="PC465_002677"
     CDS             8242..8574
                     /locus_tag="PC465_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2649963.1"
                     /translation="MSIDCISNTDLSETGFSYTLSLISGKYKMIILYCLVEFEVVRYN
                     ALKRYINTISYKTLSLSLKELEADNLIIRTEYPQIPPKVEYSLSERGKSLIPILDAMC
                     EWGERNRP"
     gene            complement(8694..9335)
                     /gene="pcp"
                     /locus_tag="PC465_002678"
     CDS             complement(8694..9335)
                     /gene="pcp"
                     /locus_tag="PC465_002678"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HDF2649964.1"
                     /translation="MKILLTGFDPFGGEPINPAQEAVERVNNNINGAEIIKITIPTVM
                     TKSVEAIDKAIQEHNPDIVISVGQAGGRFDITPERVAINIDDFRIKDNEGNQVIDTII
                     KEDGEPAYFSKLPVKAMVKHMNENKIPASVSNTAGTFVCNHVMYGILYMIDKKYPNIR
                     GGFIHIPYTTSQVIDKKNTPFMSLEEIVKGLELAIEACIIYKEDVKEIGGEIS"
     gene            complement(9356..10288)
                     /locus_tag="PC465_002679"
     CDS             complement(9356..10288)
                     /locus_tag="PC465_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HDF2649965.1"
                     /translation="MQNFINISLEIFYALMGFLMIVIAYKSFTTINNNKKYGTSLFWI
                     LISLPFIFGRLIPANIIGIILILSSLLTLSKQVVFAKYEEPDENFGKEQADKLKNKIF
                     IPSLILAFAAVVVAMSLSNFDNSSQFAIGVGSIIALISALIITKAKPATSVQDGSRLL
                     QQMGPASMLPQLLVALGALFTQAGVGEVISTMISGVVPADSRLFGVIAYVLGMVIFTM
                     IMGNAFAAFSVITAGIGIPFVLSQGGNPAIIGALALTAGYCGTLLTPMAANFNIVPAA
                     LLECKNDYIVIKYQAPVALVLIIAHILVMYFLGF"
     gene            complement(10310..10975)
                     /locus_tag="PC465_002680"
     CDS             complement(10310..10975)
                     /locus_tag="PC465_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HDF2649966.1"
                     /translation="MIKLIGILIVVIGFILKIDTLFTVLLAGVATGIVAGLDFNQIFT
                     ILGDSFVSNRGVSLFILTLPVIGVLERYGLKQRAVSLIEKLKRLTTGKVLTIYMIARQ
                     IAGALSIRMSGHPQFVRPLVNPMAQAAGLSNSDELKESDEEAIKALSAASENYGNFYG
                     QNLFAGSSGVLLIASTLTQFGYNVTGLNIVKASTIMAVIALVVATIQFTLYDKKLNKS
                     HKK"
     gene            complement(11522..11998)
                     /locus_tag="PC465_002681"
     CDS             complement(11522..11998)
                     /locus_tag="PC465_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin domain-containing protein"
                     /protein_id="HDF2649967.1"
                     /translation="MNTIIIYSSKYGCTKDCANILKNKLSDNVTIVDINNNNNKIELS
                     KFDKIIIGSSIYVGSVSKKIQVLCNDNVELLNKKQVGIFLCCGFSEQADKYLKSNFPS
                     SLLESANAIGIFGSEARLEKMKFLDKLIMKAVSKGNYDSFRISQDNIDNFLINLNS"
     gene            complement(12001..12405)
                     /locus_tag="PC465_002682"
     CDS             complement(12001..12405)
                     /locus_tag="PC465_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HDF2649968.1"
                     /translation="MKIRNKATNKKKKYVRISIALFFVFICIIIVIVSNLKPENLVVK
                     DIDINNVKNGIYTGGADNNLVKATVSVEVNNGKIQNINILKHDHLLGKPAEKITTSII
                     KQQSLDVDAITSATYSSNTIRKAVENALRKGE"
     gene            complement(12380..13009)
                     /locus_tag="PC465_002683"
     CDS             complement(12380..13009)
                     /locus_tag="PC465_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2649969.1"
                     /translation="MSIKERRKNEKEEMKKKIMDASIEIINQHGYENLSIRKIATKIE
                     YSPTTIYLYYKDKAEIISDMTNKLYNTVESNAIDIMNNCSSLPIDKQIIEIMTSFIKT
                     LSSEPEMAKSIMHSRMNIIFASENTNNTPSNNGIKMLDKFLSIGIEQGIFKKNIDKSS
                     WMLISALLGFVLCVVENKLYSLHNFSQLIENFLDILVGGLYNENSQQGY"
     regulatory      13374..13417
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            13518..14486
                     /locus_tag="PC465_002684"
     CDS             13518..14486
                     /locus_tag="PC465_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HDF2649970.1"
                     /translation="MEKRKVIIDCDPGIDDSLAILLALNSPELEVIGITTCCGNVPAN
                     IGAENALKTLQMCSSLNIPVYIGEEAPLKRKLVTAQDTHGEDGIGENFYQKVVGAKAK
                     NGAVDFIINTLHNHEKVSIIALAPLTNIAKALIKDKKAFENLDEFISMGGAFRIHGNC
                     SPVAEFNYWVDPHGADYVYKNLSKKIHMVGLDVTRKIVLTPNIIEFINRLDKKMAKYI
                     TEITRFYIDFHWEQEGIIGCVINDPLAVAYFIDRSICKGFESYVEVVEDGIAMGQSIV
                     DSFNFYKKNPNAIVLNEVDEKKFMYMFLKRLFKGYEDIIDSVEGVI"
     gene            14488..15051
                     /locus_tag="PC465_002685"
     CDS             14488..15051
                     /locus_tag="PC465_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2649971.1"
                     /translation="MKRKICVKTITLIAFGISINIIGAFIAMGLRLPVYLDSIGTIMI
                     ASLLGPKYAVVTGVFGSLISGITFDVYSLYFAPVQISTGLLAGIAFKKNFLRGLKTPI
                     GVLLFAIPTSIISSIISAFLFGGMTSSGSSYIVQILKVLGLGDVFSVFVTQVFTDYGD
                     KLLAVVLVNLGLNAVPKTLKVSLTGGK"
     gene            15059..15748
                     /locus_tag="PC465_002686"
     CDS             15059..15748
                     /locus_tag="PC465_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2649972.1"
                     /translation="MDRYSEITNKNQREIVLLKGFPCIWGKCSFCDYIDDNSNLEEEM
                     NKLNLKVLKNVTGKYGVLEVINSGSCFELPKDTLEKIKCIIKEKNIKKLFLESHWSYK
                     NRLKEMREYFEIPVVFKIGVETFDNDFRNNILNKNANFKTPQDVKEYFDSPCIMVGIK
                     GQTKEMIDKDIEIILNTFEKATVNVFINNSSSIKRDEELVKWFVSKYKFLDENPNIEV
                     LYNNTDFGVGD"
     gene            15875..16603
                     /locus_tag="PC465_002687"
     CDS             15875..16603
                     /locus_tag="PC465_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDF2649973.1"
                     /translation="MMFDRGKWNKLDYNELLEYMMSIQDIKYRDFNKKLIPGTENIIG
                     IRVPNLRKLSKEISQGNWKKFLEVAEDTYYEEVRLQGMVIGNINSNFEETLYYVKRFI
                     PKIDNWSVCDGFCSDLKSMKKYKENMYDILKKYVYSKNPWEIRFALVMFLIYYVDDKH
                     IKEIFEYCNNIQSEEYYVKMGMAWLLSICFIKCEEETFLYIKNNNLDDFTYNKMLQKI
                     IESNRVDLEKKNIIRSMKRKTRRC"
     gene            16617..17291
                     /locus_tag="PC465_002688"
     CDS             16617..17291
                     /locus_tag="PC465_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF2649974.1"
                     /translation="MNNNEDRIDKFLELQSKGFKFAEIAQNLKISQSTLRTFLNKKGY
                     KSEKGKYILKDELNYNKSLDNRNLEEEKAKEYEKSKKNTISNRKKVSTKKKISNEKAL
                     SKSVEQIEFNDTGLKNAKPKQNIKPKKDRKINITQEDLDKLCEVYDWYLEVKDYNIKP
                     KKVSNKKDVHIDDEHIDELKTTRIRIDKEIWNDFERLCSNSNFEKHQILTQALKEFMK
                     KYKNLL"
     gene            17317..18153
                     /locus_tag="PC465_002689"
     CDS             17317..18153
                     /locus_tag="PC465_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649975.1"
                     /translation="MNKIVKKSISLMIILTIFIFMLTACEKDEQPDSVDIQTEDKNEI
                     KIDEGNAKVLNIGKSEIINIDEGDKVDTSTKVENNSTFNISNVELIYNEYDENKKIIS
                     SDSKALLDMTLMPGKVAYIECGHKTFVKGVEVYAYEYEAEGKIVYVNLKENTINIRNN
                     NIKLENSSQYEVLSTSELKKVNESNEGITYQVKVKNSSSKDLGNIILKTAEVNENGEY
                     LTVNRVPSYKILKPSEETDIDILCSTKAKSVEIVGYTYDDIKEKANVDIDLKSHKVKI
                     DK"
     gene            18169..18840
                     /locus_tag="PC465_002690"
     CDS             18169..18840
                     /locus_tag="PC465_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2649976.1"
                     /translation="MKVLIVEDNKILLESVVEELSKHFETEKCEDGEEALYLVNQNIY
                     DLVILDLMLPNINGFDILKKMRVNNIDTPVLILTAKETLDDKVEAFTIGANDYLTKPF
                     YMEELVARVYAILRTNGKIKERNGLEFKSLYLDTLEKRVYIEKEEIKLQNKQFNLLEY
                     FVLNKGSILLKEQIYDRIWGIDSDATIEIVEVYVSNLRKKLSKYGYDKYIKTKRKVGY
                     IFDDK"
     gene            18830..20062
                     /locus_tag="PC465_002691"
     CDS             18830..20062
                     /locus_tag="PC465_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2649977.1"
                     /translation="MINKNVFTSTKNHLIKMYIIVVGSFLIIFSIFIYSYFRGLTYSG
                     IDSEINDELEYIVSQFKRTSFLNPIRLKDPKDMVYVYEDGRISYYTQNEYFDELLPDR
                     RLDKKNSFFKYTENGYTFRELNVDVGRYQIQIIRNIDSEMNSLRQLTSVLIIGILISV
                     IITYFVAVYLTRKALIPIETAWKNQAKFIQDASHELRTPITIVSSKLESMLKSPESTV
                     NDEVETIATAMKETRRLKKMITDLLSLTKEDSIVKVNLEEIDLEKLLEEISEDYIDIA
                     EFQEKRFVFNSKLKNKVIITDKNKLRQLILIFIDNAFKYTKLGDEIALELKEDIEDEV
                     TLLISDTGIGIKKEEIPLIFDRFFRSENVRNKDLEGSGIGLSIARMISLNLSIDINVT
                     SDVDIGTTFELSIPKKLK"
     gene            20212..20529
                     /gene="trxA"
                     /locus_tag="PC465_002692"
     CDS             20212..20529
                     /gene="trxA"
                     /locus_tag="PC465_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HDF2649978.1"
                     /translation="MAKVINTSEFRSSVEGSKGVVVVDFFATWCGPCNMLGPVFAELG
                     EEMKDKARFVKVDIDESLEIAQQFNVSTVPTMIIFKDGKPVETLIGFMPKNKIEMQVK
                     SYL"
     gene            20546..21424
                     /locus_tag="PC465_002693"
     CDS             20546..21424
                     /locus_tag="PC465_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2649979.1"
                     /translation="MRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAP
                     SIDNYLGFYDISGDELKDKFKSHIDSMDISIENKRINNIYAMGEYFTMMSGNDMYEAT
                     TVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLS
                     ELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDG
                     VFVIKDSTAPSALVPGIEIDGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQ
                     IAALNAVYYLDKLKRA"
     gene            21694..22062
                     /locus_tag="PC465_002694"
     CDS             21694..22062
                     /locus_tag="PC465_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2649980.1"
                     /translation="MENLVKIFKALSDETRLNILILVSKRNICQKGISKYLGISDSAV
                     SQHIKILKDVGIITGYKEGYYVLYHINKESFNICVDFINSMLSNSSESFIDVFDVNTI
                     HLGCSKECKSIKKCCKRREK"
     gene            22065..22436
                     /locus_tag="PC465_002695"
     CDS             22065..22436
                     /locus_tag="PC465_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HDF2649981.1"
                     /translation="MKVCIPVEENKGLDSKPYGHFGSAPIFVVCDLESGEVKSLDNGD
                     LDHEHGKCQPLKALSGTAVDAVVVGGIGQGAIIKLNGMGIKVYRAEGDTISANLDLLK
                     NGKLVEFPSDHTCSHDGCGHH"
     gene            complement(22580..23035)
                     /locus_tag="PC465_002696"
     CDS             complement(22580..23035)
                     /locus_tag="PC465_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649982.1"
                     /translation="MNINTVQGDSIEVLLRQLGATRISKVSSTLYFIKFDLGDGWEIS
                     YTYNINAKDQYFLQRIEPYPIGRGLFNDEYEIVSFISKDLKKFLNAKNSSNFKTFVEV
                     TRKVNSIIDNVEELFLNYNVDGDDLKTLNKELNDILNDIDYIEKHTKKI"
     gene            complement(23074..24339)
                     /locus_tag="PC465_002697"
     CDS             complement(23074..24339)
                     /locus_tag="PC465_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsB/NhaD family transporter"
                     /protein_id="HDF2649983.1"
                     /translation="MEFQQIIAICIFLIVMAAIITEKVNRSVAAVGGALLMIIFNILT
                     LDEGLSHIDFNTIGVLVGMMLFVAVVKNSGLFEYIAIWTAKKAKGDPWKIMICFAIIT
                     AILSAVLDNVTTVLLIGPMTIVITQILGLNPVPFLITQILASNIGGTATLIGDPPNIM
                     IGSAANLSFMDFVINLGPAVIVILAITIICFRFIYGKELVVNERAKNAILKLDEKKSV
                     KDKPLLIKSLILIAFILFGFMFHSTIHIDSSVVALTGASIMLLIGKQDVDEIMAGIEW
                     STILFFMGLFVVVGGLVEVGIINKLAQALIGLTEGHLVFTMLLILWLSAIVSSFLDNI
                     PFVATLIPLILTMQAEGIDVMPLWWATSLGACLGGNGTLIGASANVVLAGIGNKHGHP
                     ISFKEYFKIGFPLMIISIIISTVYLIIKF"
BASE COUNT         9483 a         2725 c         3792 g         8553 t
ORIGIN      
        1 tcaatatagt tttttaatat aaacaaaaaa taaaaaactt atataaataa aatgcttgtt
       61 tttcttgtat tatttatata aatattgaaa tttgtctagt tatacgtttt tattgaccag
      121 ttatgcagtt gatattgaat attctaaata ttggtgttat tttataggtg gtttaaacat
      181 attaggggga ttttatatat gatttgtatg atttatagag aatgtataaa atagtaaagg
      241 tttagagcca tgtttagtgg attgcagaat atgcatatag aatgattctt gtaaattaag
      301 ttagacatag gaaatatata atttgtattg gatgattgat tttatggtgt atgcttttaa
      361 cttctataat gggaaagtaa agatgtactc ccaatacatc tttactttag cagaagttat
      421 agttacttat aaagtacaaa aaattatata tttattagag tagataaatc taaaaaggtt
      481 tttctagaaa aatttagttt taattgtatc tacttactaa taataagact tgatgtaagc
      541 aggtttcaac taccgtttct ccatattctg atataaaatc atctaactgt gtatctaaaa
      601 aattacaata atcatatgaa ctactgatgt aagcagttag tatatgtgta catttgtcta
      661 tttctccaat aaacatatta tccatccccc taaaaaattt agtaaaaata aaaagtcgca
      721 ttctattagt caattaacat aatttataaa attttttagt actagtttct ataacttaac
      781 tccttaaggt taaatattcc cagttttacc aatttagttt tattctacaa gtatataata
      841 ctagaagatg cttcattatt caacatgctt gtttgagaat agaaaatatt ctaaaattat
      901 aattgttttt aaaaataaga ttcaagataa ataaagttat atgcaactat ttaataatct
      961 ttccataata aggacagtag gttctattct taaaaaactc catctttaaa tttaaagaat
     1021 aactacaatt tgaacaacaa taaaatttcc aatcaataaa aatatcaaaa ataataaaaa
     1081 taattgaaaa tgtataattt cccagaaaaa taataaatgt aactccaata ataaacacac
     1141 ctataaatta taaaataatt taagctttat ttaaggttag tattatattt atataagatt
     1201 taagttttaa tatatatgtg taattaaaat gatttaggag gagaaatata ttggtaaatt
     1261 gggaaataaa aaaattggct aaatctaaga gtatgtttat atctctaggc atattagtgt
     1321 taatactaat gattagtatc tttattgcgc ctgttttaga aacagaaagt tattatatag
     1381 ataaagaaaa aggacgtata gaagatacga gaagtggtat cgacataggt aatgagaaat
     1441 ttcaaaataa gattaatgtt ttaaagcagt tttcaaatca aacagataca ggtgaatttt
     1501 ctaaaaaaat tgaattaatg tcaaagaaaa aacttgataa tctaagtgtg aatgaatata
     1561 aggatattag tttttggaaa gtatttaact atagagttac aaattcactt ataaatgtag
     1621 gaatgttaat cattatatct ataattatat ccaatattta cgtagatgaa gtcgttactt
     1681 cggtaaaaga tatcatacta tcatcaaaag agaagaaaaa agcattaaag tctaaaatat
     1741 ttgttgcttt attagttcca ttagtaattt attctgttta tttaatggga atatttatta
     1801 taacttgtat gcaacaagga gtacctgtta atggagactt agaatctttt agaatagtag
     1861 acaatgtagt tgcattgaaa actaatttaa gtataacaaa gtatgtaata ttaaatatag
     1921 gcatagagct tttgatgttt gaaggatggg ccatgatagc catatttggg tcttttataa
     1981 gtaagtcttc aatatcttca ataagttttt ttatatttat tatatctata actaagataa
     2041 tgtcggtaat ccatatatta cctaaaaaat tactttcagt tgtatcaaat gtaaattatt
     2101 atgatttgat atttggtttt aataaaataa taggaaatta tctaggtgat attatgatat
     2161 ttaaagtgaa tatagacatt gtcaatatag caataggact tttgatggca atattgatag
     2221 gtactatgtc attatgtttt ttagtaataa aatcagatta tataagtaga taaaagggga
     2281 gttaagatga ataaattaga aatagaaaat ctttcaaaga tatatggtaa aaaagtagca
     2341 aacgacaaga ttacagtaac tctggaaaat ggagtttatg gtcttctagg accaaatgga
     2401 gcaggaaaat ctacattaat gaaacaaata acaacgttga taaaacctga tgaaggtcag
     2461 atactttata atggtgagga tatatttaaa atggatgctg attatagaaa tattttagga
     2521 tatttgccac aagaatttgg agtttataaa aattttacag caaaagaatt tttacagtat
     2581 attggagctt taaaaggttt aaggggaaaa tatttaaata gtaagatagg agaattatta
     2641 gatttagtag gtctttatga tgtgagaaat aagtctatag gaaaattctc aggaggtatg
     2701 aagaggagag ttgggatagc acaagtttta ctaaacgacc ctaagataat agtccttgat
     2761 gagccaacag caggtcttga cccacaagaa agagctagat ttaggaattt aatagcaaaa
     2821 atgtctagag ataagataat aatactttct actcatataa tttccgatat agaatcagtt
     2881 gcaaaggaaa caataatgat taaagatggc aaactcctaa tgaaaggaac acacaaagac
     2941 atattaagtc acatggaaaa taaagtatat aatgttcaag ttaaaaatga atgtgaagtt
     3001 gatgatatac aatctaaata taaggttgta agtattcaaa gtgatattaa ttcaatagta
     3061 cttagaattg tttcagagga tattctaagc gaggataata tacaaccagt tcaagcaaaa
     3121 ttcgaagatg tatacatgtt ttattttgat ttagaagatg caagggaggt gtagtagaaa
     3181 tgatgtattt agttaaagct gaaatgataa aaatattaaa atcaaagagt gtttggataa
     3241 tttggctgtt tttaatattt tttggatttt ttctgattag aaagtttgat gttttagata
     3301 cttatgcaga tatattttac aagatagaag gctcaatacc tctaataggt ttgataatgt
     3361 ttataataac ttctggaaat tacattaaag aatatgattc taatatgaca ggtttaataa
     3421 atacaactaa aaagggaaaa aaatcagtag tattatcaaa actagtagct aatggattaa
     3481 ttttatctat tattaatatt tcttttatat tgttagtagg aattagaggt tttagttttt
     3541 ttgattttaa aaatttaaat gaaccgattc ataacttatg gtactttgga aatagtaatt
     3601 taaatcttac agtaatacaa atgtatataa ttgttatatt gactactatt tttgcttctt
     3661 ttatatttgc acaaataggc ttaacacttt catctatatt taaatcggct gtaattccat
     3721 ttatactagg tggattgata atggcaattc catactttag tgtaggtttt ataccagata
     3781 aagctataaa atttatgtca gtgactccaa attggattat gatgagccaa caaatggtta
     3841 agtataatgt accaagtatt ttgatagttt tttctatagt aatctcaatt atattaatga
     3901 tagtgttaac taaaataaca tatgaaaatt ttacatcaag caaaaggttt taactaaaaa
     3961 taatagtaat tttatttata ttttagttta attaaaaata agataaatga attttagata
     4021 aaatatatgc taatatatat gtaaattatt acaggaggtt gtttatggaa aatcgtgttt
     4081 taataataga tgatgaagta gaaatattga agcttttaga aactgtccta aaaaaagaag
     4141 gccttaataa tatatatact gcaaaaacta aaaaagaagg attagaatta tttaaaagta
     4201 ttaatcctga tttgattgta ttggatatta tgttaccaga tggcgaaggt tatgatattt
     4261 gtaaagaaat aagaaaaacc tccaattctc caataatatt tttatcagct aaaaccgaag
     4321 aattagataa gttacttgga ctagcgattg gaggagatga ttatgttaca aaacctttta
     4381 gccctaagga agtggctttt agagttaaag cgcatttgag aagattaagt tattttagtg
     4441 atgctcaaaa cgaaagtaaa aatctaaata ataatgaaga aaaaattata tcatttggcc
     4501 catatatatt aaatgaaagt agggcagaac ttataaaaga tggaaaatct ataggactgt
     4561 ctgcaaagga actaaaaatc ctatctttat ttgcacataa tcaaaatcaa attataagta
     4621 aagaaaaact atgggataaa gtgtggggag aagattatgt tggatttgac aatactataa
     4681 tggttcatat aagaaaaatt agggaaaaat tagaggataa tccttcaaaa cctgaatata
     4741 ttctgacaat aaaaggtctt ggatataaat tagcagtaaa ggaagattag aatatgaagt
     4801 ggaagattac tagaaatttt atatttacaa ttgtgtttgt agctatatca gtagtaatta
     4861 taaatatcat atctatattg tatgtgattt caactaatag cttttttaaa gttgtagatt
     4921 ctggaaataa tcctgaagaa tttgcacgtt cttttgaaaa agatttatat gaaaaagatg
     4981 gagaatttaa actatctaag attggagctg aaaaattaga aaaatcaaat tcctggatac
     5041 aggttttaaa tgatttagga gaggaagttt atggagtaaa tgtgccaaag gatactccaa
     5101 aaaaatatac accctttcaa atggtgaata attacaagta tatagaaaca aagtatgtta
     5161 attttgtact agaaaaatat ttaaacaaaa aacatctaaa cataatagta ggtataccta
     5221 gtagagatat atcaagaata attttaacct attctcaaaa taacattaaa aaaactttaa
     5281 ataaagttat cattataaca ctagtaattg atagcgtggt agctttaggc gtaggatatt
     5341 tatttagtag aaaacttaca aaaccaattt caagcgtact atggagtatt gagactatgg
     5401 ctaatggaaa ttatagttta tatcttaagg acagaggtat atatgaagaa gtttttaaaa
     5461 atataaatat gttagctgat actttaagag taaatgaagt tgagagaaaa gaaaatgaag
     5521 agttgagaga ggaatggctg gcaaatataa cacatgatat aaagacacct ctagcatcta
     5581 tacaagggta tgcagagata attaatgaca aagattatga gtttgaagaa gatgaaatac
     5641 aagagtatac agaaattata tataataagt ctaagtatat aaaagattta gttgatgatt
     5701 taaatttatc tactcgatta aaaaataata ctatagttct ggacaagaaa aaaataaatt
     5761 tagtcagttt agtcagagat ataataattg atattttaaa tgataataga tataaaaata
     5821 ggaatattga atttgaaagt aatgaagatt taattgaagt atatgtagat tcaatcttat
     5881 tcagaagggc tataaccaat cttatattta attcaatagt tcataatagc gaaggaactt
     5941 tgataagtgt agaaattgta aaaaaagata atatagaaat tataataaaa gataatggaa
     6001 ttggaataag caaaagtgat ttgaaacata tttttaaaaa atattataga ggtactaata
     6061 caggtgagat gcataaaggt tcaggtcttg gtatggctat ttctaaagaa ataatagaga
     6121 ttcataaagg taaaatttat gtaagtagtg aaattggaat aggaacaaaa attattatag
     6181 agataaaaca aaattaggag atatgatatg gattttttta aaaaaggtat aagtgggttt
     6241 actattaaga ttttagcatt aatatttatg acatttgacc atatagcagc atttatgcca
     6301 caaacaatgc aaataccaat ttggtttcat tgggtaggca gaatatcagc accactgttt
     6361 atatttatgg ctgttgaagg attttatcac actagtaaca gaaaaaaata tataagtaga
     6421 ttgtatattt ggtctgttat tatggctata ggaaatcaaa taattaataa tgtattttca
     6481 catccagaag gagctataat tataaataac attttttcaa cattattttt aatagcgatt
     6541 tatttacaag caatagagtt cataaagaaa tttagaaaag agaaagaaat taaatatttt
     6601 attataggat tattgatgat aatcattcct ataattttag gaatatttac agtagcttta
     6661 ctttttaaag tcactaacag agttattgct ttatttatga ttttggtacc agtaccattt
     6721 ttagtagaag gtggaccaat ttggattata cttgggatta ttttttattt gtgtagaggg
     6781 aaaaagttca gtttgagtat ttgttatgct ttaatgtgta tatttatatt tacaacaatg
     6841 tcaaatggag attatagttt aaaaaattct attttacaaa attaccaatg gatgatgatt
     6901 gcttctctac ctttaatgtt actttacaat ggagaaaaag ggaagagtat gaagtattta
     6961 ttttatttat actatccaat ccatgtatat atattgtata tcttaggaat atacttaata
     7021 aatggttttt gattgtaagt gatattttta atacaaaatg aacaatatga ggattgtttt
     7081 aggtctatta aaattgttat ttagatgaga tttgtagaat atttaaattt atgagcagaa
     7141 attcagttat tgtaatttca ataacattag aatataatat tataatttat ttagaaatat
     7201 atgatgttat acatggtttg gttattaatg taataataaa acagaggttt gatataaaat
     7261 tcaatacctc tgttttagtg ctttttatcc tacatttatg cttattttat ttataaatta
     7321 gtgttttgtt ttaattaata ttagtacatt ttttatttat tttataaaat tagtcataat
     7381 tgtttcttca tattgtggtt ctttaattcc agctttttta cctgctgata tacacttaag
     7441 aagccatgcc atgttttctc ctagagttcg catagtctgt aatccttctt catccttcat
     7501 aacatcctct ggagtaaagc catgtacctg gttccaatac tgtgatgata caataggcat
     7561 attgctgatt gaaaaatatt tatttagttg gtcaaatgtt gcacttgcac caccacgtct
     7621 acatgacaca actgaagcac ctaattttgt agccatgcga cttccagcta tgaaaaatag
     7681 acggtcaaga aaagaagtta attgaccagt tgcactagaa aagtaaacag gagaaccaat
     7741 aataatacca tcaatattat ccagatcttc aatcaattca ttaactttat catttcgaat
     7801 gcattttcca gtttcaaaac aggatgcgca actaatacat cctgggattg tttctttacc
     7861 taaatacagt atttctgttt taatatcgtg tttactcaat actttagtaa tctcatttag
     7921 tgctgtataa gtacatccat attggtttgg gctaccgttt atcaataaaa ctttcattat
     7981 aaatttcctc caatgaattt tatttaatag attttctaag agatattatt ttttataaaa
     8041 taggattttc atgaatatta tcaatttata tagaaatgtc taatcttaga atcctattta
     8101 aaataacttt tttttagtaa atacacctcc tattataaaa ttgactttca attattctta
     8161 cactataatt ttattataaa ttattctaaa aacaagtacg cacatttttg ttcaatacta
     8221 accaaaagga gagtgtaata tatgagtata gactgtatat caaatacaga tttaagtgaa
     8281 acaggattta gttatacact ttcactgatt agtggtaaat ataagatgat aattctttac
     8341 tgtcttgtag aatttgaagt tgtaagatat aatgcattaa aacgttatat aaatactatc
     8401 tcctataaaa ctttgagttt atcattaaaa gaattagaag cagataactt gattattcgt
     8461 actgaatatc ctcaaatacc tcctaaggta gaatatagtc tatcagaaag gggaaaatct
     8521 ctgattccaa ttttagatgc aatgtgtgag tggggagaga ggaatagacc ttaattttgt
     8581 atctgtagat accataaaaa gactgtgagt aaaattgttt gaataatcta ctcacagtct
     8641 atatttaaat taatagttag tatttttaat ttataaaaat actaaaaaat ttattatgaa
     8701 atttcaccac caatttcttt tacatcttct ttatatataa tacaagcttc tatagctaat
     8761 tctaagcctt ttactatttc ttctaaagac atgaatggtg tatttttttt atctattact
     8821 tgtgaagttg tatatgggat gtgtataaat ccacccctta tattaggata tttcttgtct
     8881 atcatataaa gaattccata catcacatga ttgcaaacaa atgttcctgc agtgtttgaa
     8941 acactagctg gaattttatt ttcattcata tgttttacca tagcttttac aggcaatttt
     9001 gaaaaatatg caggttcacc atcttctttt ataatagtat ctataacctg gttaccctca
     9061 ttatctttta ttctaaaatc atctatattt atagcaactc tctcaggtgt aatgtcaaat
     9121 ctacctccag cttgtccaac tgatattact atatctggat tgtgctcttg aatagcttta
     9181 tctatagctt caacagattt tgtcataact gttggtatag ttatctttat gatttctgca
     9241 ccgtttatat tattattgac cctttcaact gcttcttgag ctgggtttat tggttctccg
     9301 ccaaatgggt caaatcctgt taacaaaatt ttcattattt tacctcctaa ttatattaaa
     9361 atcctaaaaa gtacattact aatatgtggg ctataattaa taccaaagca actggagctt
     9421 gatattttat aacaatataa tcatttttac attctagcaa ggctgctgga actatattaa
     9481 aattagcagc cattggagta agtagagttc cacaatatcc tgctgttaat gctaatgctc
     9541 caattatagc aggatttcca ccttgagaca atacaaaagg aataccaatt cctgccgtta
     9601 tgactgaaaa tgcggcaaat gcatttccca ttatcatggt aaatataacc atacctaata
     9661 cataagctat aacaccaaat aatctgctat cagcagggac tacaccagat atcatggttg
     9721 aaataacttc accgactccg gcttgagtaa ataaagctcc caatgcaact aaaagttgtg
     9781 gtaacatact agcaggtccc atttgttgaa gtaatcttga gccatcttga actgatgtag
     9841 caggttttgc cttagttatt ataagggctg atattaatgc aattattgaa cccacaccta
     9901 ttgcaaattg agaagaatta tcaaaattag aaaggctcat agctactact actgcagcaa
     9961 atgctaatat taatgatggt ataaatattt tatttttaag tttgtctgct tgttcttttc
    10021 caaaattttc atctggttct tcatactttg caaatacaac ttgtttagaa agtgttaata
    10081 aactagataa tattaatatt attcctatta tattggctgg aatcaatcta ccaaatatga
    10141 atggcaatga tataagtatc caaaataatg atgtaccata tttcttattg ttatttatgg
    10201 tagtaaaaga cttatatgct ataacaatca ttaaaaatcc cattagtgcg taaaagattt
    10261 ctaatgatat gtttataaaa ttttgcattt ttattcctcc taaataaaac tattttttat
    10321 gacttttgtt taatttttta tcatataagg taaactggat tgtagccact acaagtgcta
    10381 ttactgccat aatagtacta gcctttacaa tattaagtcc agttacattg tatccaaatt
    10441 gagtcagagt agatgctata agtaatactc cactactacc tgcaaataag ttttgaccat
    10501 aaaaatttcc atagttttct gatgcagcag ataatgcctt tatggcttct tcatccgatt
    10561 cttttagttc atcactatta cttaaaccag cagcttgtgc cataggatta acaagtggtc
    10621 ttacaaattg aggatgtcca ctcattctta ttgatagagc accagctatt tgtctagcta
    10681 tcatgtatat agtaagtact tttcctgttg taagtctttt taatttttct attaaagaaa
    10741 cagctctttg ttttaaacca tatctttcta atacaccgat tactggcaat gttaatatga
    10801 ataatgatac acctctgttt gagacaaaag aatctcctaa aattgtaaaa atttgattaa
    10861 aatctaatcc tgcaacaatt cctgttgcca ctcctgctaa taatacagta aatagtgtgt
    10921 caattttaag tataaatcca attacaacta tcaatatacc gattagtttt atcataaatt
    10981 gttctccttc catttctata tgttttaatt taaatttatt taatggataa agttaaactc
    11041 tttttatagt atttgcgtta ataggactat tattataaaa tttaataaaa aatagggaag
    11101 atgtttttaa gtatcaaagt aaataatggt tgtgtatagg aatttgaata acaaagatta
    11161 tattttaagc taatatgaat tgattttgta agtctatagt ttaagtatat gtcaatattt
    11221 gaaataggtt ttaaattaga tattatatta taaaaagaga atgtgccaaa catagagaca
    11281 agtgtatttt tcacttttga aatgataaaa atatatttga tttcatacaa aaagagagtg
    11341 tctaatgaat tttttagttc attagacact ctctttttgt tatgattaat aaagcatata
    11401 ttaagtgcta gtttcattag atttcactaa gaaaaataaa attttgataa agtttaaaga
    11461 ctattttgag caatattact tataaataaa agaatttatc atagagataa ttagttttat
    11521 tttagctatt aagatttatt aaaaaattat ctatattatc ctgtgatatt ctaaaactgt
    11581 cataattacc ttttgaaaca gccttcataa taagtttatc taaaaatttc attttttcta
    11641 atcgagcttc actaccaaaa attccaatag catttgcact ttctaataag gatgatggaa
    11701 aatttgattt taaatattta tctgcttgtt cagaaaagcc acagcaaagg aaaatgccaa
    11761 cttgtttttt gtttaataac tctacattat cattacatag cacttgtatt ttttttgaaa
    11821 ctgaaccaac atatatagaa cttccaataa taattttatc aaattttgat aactcaattt
    11881 tattattatt attattaata tcaacaatag tgacattatc tgatagttta ttttttagta
    11941 tatttgcaca gtcttttgta caaccatatt tacttgaata tataataata gtattcataa
    12001 ttattctccc tttcttaaag cattttctac agcttttcgt atagtattac tgctataagt
    12061 tgcagaagtt atagcatcca catctaaaga ctgttgttta ataatacttg ttgtaatttt
    12121 ttcagcaggt ttacctaaaa gatggtcgtg ttttaagata ttaatatttt ggattttacc
    12181 attattaact tcaacagaca cagtagcttt taccaagtta ttatcagcac ctccagtata
    12241 aatgccattt ttaacattat taatatctat atcttttact accaagtttt ccggctttaa
    12301 gttgcttaca attacaataa taatgcatat aaatacaaag aatagagcaa tagatattct
    12361 tacatatttt ttctttttat tagtagcctt gttgcgaatt ttcattgtaa agtcctccca
    12421 ctaaaatatc taagaaattt tctataagtt gagaaaaatt atgtaaagaa tatagtttat
    12481 tttcaacaac acataaaacg aatcctaaca atgcacttat aagcatccat gagcttttat
    12541 ctatattttt tttgaatatt ccttgttcaa ttccaatgga aaggaattta tcaagcattt
    12601 ttataccatt attgctaggc gtattgtttg tattttcaga tgcaaatata atattcattc
    12661 tactatgcat gatagatttt gccatctctg gttcactaga aagagttttt ataaagctag
    12721 tcataatttc tatgatttgt ttatctattg gtagtgatga gcaattattc ataatgtcaa
    12781 tggcattact ttctactgtg ttataaagtt tattggtcat atcgctgata atttctgctt
    12841 tgtctttgta gtaaagataa attgtagttg gagaatattc tatttttgta gcaatttttc
    12901 ttattgataa attttcatat ccatgttggt ttataatttc gatgctagca tccataatct
    12961 ttttcttcat ttcttctttt tcatttttac gtctttcttt gatactcata taattacctc
    13021 tttgcttaac ggtgttaagt taatttacac tgttattgta taatttaatt ttaatactgt
    13081 caataaatta ttaaataata taagttaata tatttttatg gataataaat taatgttatt
    13141 aattgtaata tttaagatat tattgtataa taataatcgg tttaaatgcg ccacatctta
    13201 ttaaagttgg ttcataattc taaataaact ttaataagat acactaaaat ataataaatt
    13261 cttttatgct ataaaattta ttttatagct attaaatcag atgtttaaaa attttttaac
    13321 ggtctatagt ttttaagagt ctatagtaag tagactaaaa atatgatttt acatctgtac
    13381 ttgttcgaga actccaagta taaaaaacta aggaattata tagtggcagt atataattaa
    13441 tacccttaga cacacctttt tgaaagtgga aaaaagatgt gtagttctcc tcgaccacaa
    13501 atcaaggagg ataaaaaatg gaaaagagaa aagtaataat tgattgtgac ccaggaattg
    13561 atgattcttt ggcaattctt ctggctttaa actcaccaga gctagaagtg attggaatta
    13621 ccacatgttg tggaaatgtt ccagcaaata taggtgcaga aaatgcacta aaaacacttc
    13681 aaatgtgttc ttcactaaat attccagtat atataggaga agaagcacca ctaaaaagaa
    13741 aacttgtaac agctcaagat acacatggag aagatggtat tggagaaaac ttttatcaaa
    13801 aggttgtggg agctaaagca aaaaatggag cagtggattt tataataaat actttacata
    13861 atcatgaaaa agtatcaata atagcacttg caccacttac aaacatagct aaagcactta
    13921 ttaaagataa gaaagcattt gaaaatctcg atgagtttat atctatggga ggagcattta
    13981 ggattcatgg aaattgctct ccagtagcag agtttaatta ttgggtagac ccacatggag
    14041 cagattatgt ttacaagaat ttatctaaaa aaatccacat ggtaggttta gatgtaacta
    14101 gaaaaattgt acttactcct aatattattg agtttataaa tagacttgat aagaagatgg
    14161 caaagtatat aactgaaata actagatttt atattgattt ccattgggaa caggagggaa
    14221 taattggctg tgtgataaat gaccctctag cagtagcata ctttatagat agaagtatat
    14281 gtaaaggatt tgaatcatat gtagaagttg tagaagatgg aatagctatg ggtcagtcta
    14341 tagtggattc tttcaatttc tataaaaaaa atcctaatgc aattgttcta aatgaagttg
    14401 atgagaagaa atttatgtac atgtttttaa agaggctttt taaaggttat gaagacatta
    14461 tagactctgt ggaaggagtg atatagtgtg aaaagaaaaa tatgtgtaaa aactattaca
    14521 cttatagctt ttggtatttc tataaatata ataggcgctt ttatagctat gggattaaga
    14581 ttacctgtat acttagattc aataggaact ataatgatag cttcactttt aggacctaaa
    14641 tacgctgttg ttacaggtgt gtttggaagt ttaataagtg gaattacgtt tgatgtgtat
    14701 tctctctatt ttgcaccagt tcaaatatca accggattac ttgctggaat agcatttaaa
    14761 aagaattttt taagaggttt aaaaactcca ataggagtac ttttatttgc cattccaaca
    14821 tctataataa gttcaataat ttcagcattt ttatttggag gtatgacctc ttctggttca
    14881 tcatatatag tgcaaatctt gaaagtgtta ggactgggag atgtttttag tgtgtttgta
    14941 acccaagtat ttactgatta tggagataag ctgttagcag ttgttttagt gaatttagga
    15001 ttaaatgcag ttccaaaaac tttaaaggta tcattgactg gaggaaaata gatagaaaat
    15061 ggatagatat agtgagataa caaataaaaa tcaaagagaa attgttctgc ttaaaggatt
    15121 tccttgtata tggggaaagt gttctttttg tgattatata gatgataatt ctaatttaga
    15181 agaagagatg aataaattaa atctaaaggt tttaaaaaac gtaactggga aatatggagt
    15241 tcttgaagtc ataaattctg gaagctgttt tgaattacct aaggatactt tagaaaaaat
    15301 aaagtgtatt ataaaagaga aaaatataaa aaaattattt ttagaaagtc attggtctta
    15361 caaaaatagg cttaaggaaa tgagagagta ttttgaaatt cctgtggtat ttaaaattgg
    15421 agttgaaacc tttgacaatg attttagaaa taatatttta aataaaaatg caaattttaa
    15481 gactccacaa gatgtaaaag aatattttga ttcaccttgt attatggttg gaataaaagg
    15541 acaaacaaaa gagatgatag ataaagatat agagattatc ctaaatactt ttgaaaaagc
    15601 gacagtgaat gtttttataa ataattcttc tagtataaaa agagatgaag agttagtgaa
    15661 atggtttgtt agtaagtata aattcttgga tgaaaatcca aatatagaag ttttatacaa
    15721 taatacagac tttggtgtag gagattagca ttaatttagt ttaaatttaa aattgaaaag
    15781 tttcttatgt ttttgaaaaa gcttctaata gttagaagct ttttttgtag agttttatgt
    15841 tacaataaga aaaaaggaat taaggagcaa ttaaatgatg tttgataggg gaaaatggaa
    15901 taaattggat tataatgaac ttttagaata tatgatgtct atacaagata taaaatatag
    15961 agattttaat aaaaagctta tacctggaac agaaaatata ataggtatta gagttcctaa
    16021 tttaagaaag ttatcaaaag aaataagcca aggaaattgg aagaaatttt tagaagtagc
    16081 agaggataca tactatgaag aagttaggct acaaggtatg gtaattggca atataaatag
    16141 taattttgaa gaaactttat actatgtaaa aagatttata cctaaaatcg ataattggtc
    16201 agtttgcgat ggattttgtt ctgatttaaa gtctatgaaa aaatataaag aaaatatgta
    16261 tgatatactt aaaaaatatg tttattcaaa gaatccatgg gaaattagat ttgcattagt
    16321 tatgttttta atatattatg ttgatgataa acatattaaa gaaatatttg aatactgtaa
    16381 taatatacaa agtgaagaat attatgttaa aatgggtatg gcatggttgc tatcaatttg
    16441 ttttattaaa tgtgaagagg aaacttttct ctatataaaa aataataatt tagatgattt
    16501 cacttataat aaaatgctac aaaaaataat tgaatcaaat agagtagatt tagaaaagaa
    16561 gaatataata agaagtatga aaagaaagac aagaagatgt tgacggagga atattaatga
    16621 ataacaatga agacagaatt gacaaatttt tagaacttca aagcaaagga tttaaatttg
    16681 cagagatagc tcaaaatcta aagattagtc aaagtacttt aagaactttt ttaaataaaa
    16741 aaggatataa gtcagaaaaa ggtaaataca tattaaaaga cgaattaaat tataataaaa
    16801 gtttggataa tagaaacttg gaagaagaga aagctaagga gtatgaaaaa agtaaaaaga
    16861 atactataag taatagaaaa aaagtaagca ccaaaaaaaa gatttctaat gaaaaggctt
    16921 taagtaaaag tgttgaacaa attgagttta atgatacagg cttaaaaaat gcaaagccaa
    16981 aacaaaatat taagcctaag aaagatagaa aaataaatat aactcaagaa gatttagata
    17041 agctttgtga agtatatgat tggtatttag aagtaaaaga ttacaatata aagcctaaaa
    17101 aagtatctaa taaaaaagat gtacatatag atgatgaaca catagatgaa ttaaaaacaa
    17161 caagaatacg tatagataaa gaaatatgga atgattttga aagattatgt agtaattcga
    17221 attttgaaaa acatcaaata cttacacagg cattgaaaga atttatgaaa aagtataaaa
    17281 atctactata aaatactact atatgaggtg cttaatatga ataaaatagt aaaaaaatca
    17341 atttctctaa tgattatatt aacaatattt atttttatgt tgacagcatg tgaaaaagat
    17401 gaacagcctg attcagttga tattcaaaca gaagataaaa atgagataaa aatagatgag
    17461 ggaaatgcaa aagtattgaa tataggaaaa tcagaaatta taaatataga tgaaggtgat
    17521 aaagtagata catcaacaaa ggtagaaaat aattcaacat ttaatatatc caatgttgaa
    17581 ttgatatata atgaatatga tgagaataaa aaaattatat cttcggatag taaggctttg
    17641 ttggacatga ctttaatgcc tgggaaagtt gcttacatag aatgtgggca taaaactttt
    17701 gtaaagggtg tagaagttta tgcatatgaa tatgaggcag agggtaagat tgtgtatgtt
    17761 aatttaaaag aaaatactat taatataaga aataataata ttaagctaga aaatagtagt
    17821 cagtatgagg tgctatctac atcagaactt aaaaaagtaa atgaatcaaa tgagggaatt
    17881 acgtatcaag taaaagtaaa aaattcatca tcaaaagatt taggaaatat tattcttaag
    17941 acagcagaag ttaatgaaaa tggagaatat ttaacagtaa atcgtgtgcc atcatataag
    18001 attttaaagc cttcagaaga gacagatata gatatattgt gttcaacaaa ggcaaaaagt
    18061 gttgaaatag tgggatatac gtatgatgat ataaaagaaa aagccaatgt ggatattgac
    18121 ttaaaatctc ataaagttaa gatagacaaa taaaggtagg ggatacttat gaaggtttta
    18181 atagttgaag ataataagat acttttagaa agtgtagtag aagaacttag caagcatttt
    18241 gaaactgaaa agtgtgaaga tggagaagaa gctttatact tagtaaatca aaatatatat
    18301 gatttagtca ttttagactt aatgcttcct aatataaatg gatttgatat cctaaagaaa
    18361 atgagagtta ataatataga tacacctgta cttatattga cagcaaaaga aacattagat
    18421 gacaaagtag aagcatttac tataggagct aatgattatt tgacaaaacc tttttatatg
    18481 gaagagttag tagctagggt atacgctata ttaaggacta atggaaaaat aaaagaaaga
    18541 aacggattag aatttaaatc tttatattta gatacactag aaaaaagagt gtatattgaa
    18601 aaagaagaaa taaaacttca aaacaaacag tttaacttgc ttgagtattt tgtattaaat
    18661 aaaggttcaa ttttattaaa agagcagatt tatgatagaa tatggggaat tgattcagat
    18721 gcgactattg aaatagtgga agtatatgta agtaatctaa gaaaaaaact aagtaaatat
    18781 ggatatgata aatatattaa aactaaacgt aaggtaggat atatattcga tgataaataa
    18841 gaatgtattt accagtacta aaaatcattt aataaaaatg tatattattg tagtaggtag
    18901 ttttttaata atcttttcta tatttatata ctcatatttt aggggactta catatagtgg
    18961 aattgatagt gagataaatg atgaacttga atatatagtc tctcaattta aaagaacttc
    19021 atttttgaac ccaataagac tgaaagatcc taaagatatg gtgtatgtat atgaagatgg
    19081 aaggataagt tactatactc aaaatgaata ttttgatgag ttacttccag atagaagact
    19141 agataaaaaa aattcgtttt ttaaatacac agaaaatgga tatactttta gagaattaaa
    19201 tgtagatgta ggtagatacc aaatacagat aattagaaat atagattctg agatgaattc
    19261 tttaagacag cttacatctg ttcttataat tggaatatta atttctgtaa taattactta
    19321 ctttgtggct gtatatctca ctagaaaagc tttaattcca atagaaacag catggaaaaa
    19381 tcaagctaag tttatacaag atgcttctca tgaattaaga acaccaataa caatagtttc
    19441 atcaaaatta gaaagtatgt taaaatcccc agaaagtaca gtaaatgatg aagttgaaac
    19501 aatagctact gcaatgaagg aaactagaag acttaaaaaa atgataactg atttattgtc
    19561 tcttactaaa gaggactcta ttgttaaagt taatttagaa gaaatagatt tagaaaagtt
    19621 attggaagaa atatcagaag actatattga cattgctgag tttcaggaaa aaagattcgt
    19681 gtttaattct aaactgaaga ataaagttat aataacagat aaaaataaat taagacaact
    19741 tatattaatt ttcattgata atgcctttaa gtatacaaaa ttgggtgatg agatagcatt
    19801 agaattgaaa gaagatatag aggatgaggt aactttactt ataagtgata ctggtatagg
    19861 cataaaaaaa gaagagatac ctcttatatt tgatagattt tttagaagtg aaaatgtaag
    19921 aaataaagat ttagaaggtt ctggaatagg actttcaata gctcgcatga ttagtttaaa
    19981 cttatctatt gatataaatg taacttctga tgtagatatt ggaactacat ttgaattgtc
    20041 aataccaaaa aagttaaaat aataaaaata taaaaaattg tttttagaaa tgaagaatgg
    20101 gtatactaat tagtataaaa tataaaaaga ccttataaaa gtaaatttat atttataaat
    20161 ttcatagtat aattatatag ggataataaa gtttaatagg aggatttaaa aatggcaaaa
    20221 gttataaata catctgaatt tagaagtagt gttgaaggta gtaagggagt agttgtagtt
    20281 gatttctttg caacttggtg tggaccttgt aacatgttgg gacctgtatt tgcagaatta
    20341 ggtgaagaga tgaaggataa agctagattt gtaaaagttg atatagatga gagcttagaa
    20401 atagctcaac aattcaatgt atctacagta ccaactatga ttatatttaa agatggaaaa
    20461 ccagtagaaa ctttaattgg attcatgcca aagaacaaaa ttgaaatgca agtaaaatca
    20521 tatttataaa aaatgggtga gtattatgag atatgatata gctataatcg gcagtggtcc
    20581 agctggattg tctgctgcta taaatgcaaa aataagaaat aaaacaatta tcatgtttgg
    20641 taatgataat ttaagtaata agcttgttaa agctccttca atagataatt atttaggttt
    20701 ttatgatata agtggtgatg aattaaaaga caagtttaaa tcacatatag atagtatgga
    20761 tatttcaatt gaaaataaaa gaataaataa tatttatgct atgggagaat actttacaat
    20821 gatgtctgga aatgatatgt atgaagctac tactgtaatc cttgcaactg gggtagagta
    20881 tactagacca atcaagggtg aagaagaatt tctaggaaga ggtgtgggct actgtgctac
    20941 atgtgatgca ccactttata gaaataaaaa ggtagcagtt ataggatata atgaagaatc
    21001 taaagaagaa gcaaattttt taagtgaact cacttcaaag acttatttta tacctatgta
    21061 caaaaaagat aatcttatga gaagttcaga taacctagat gattctattg aagttataca
    21121 tgacagacca gtacagatag atggagataa acttgtaaac aaagtatctt ttaaagaaaa
    21181 ccacattgaa gttgatggag tattcgttat aaaagatagt acggctccaa gtgcattggt
    21241 tcctggaata gagattgatg gcattcatat taaagttgac aataatatga agactagtat
    21301 agatggatgc tttgctgctg gagattgtgt tggaaaacca tattcttata taaaagcagc
    21361 tggtcaaggg caaatagcag ctttaaatgc tgtttactat ttagataaat taaagagggc
    21421 ttaatattta tattgattaa ctttttaaag atatttataa aaaactgtct tgaaataatt
    21481 ttattatttc aagacagttt tttattttta agttattaat aaaagtattt taaaatctat
    21541 atgtaattac ttttattaat aaaactcaaa gttatattag taaaaattgg aattatttat
    21601 aatatactcc aaaatttaaa aataatggtt gaaaaatcta attaagagta ctataattta
    21661 attaagtaat tacttaatca aaacgaggta cttatggaaa acttggttaa aatatttaaa
    21721 gcattgagtg atgaaactag acttaacata cttatattag tatccaagag aaatatatgt
    21781 caaaagggga tttctaaata tctagggatt tcagattctg ctgtttcaca acatataaaa
    21841 atattaaaag atgttgggat aataacagga tataaagaag gatactatgt tttatatcat
    21901 attaataaag aatcatttaa tatatgtgta gattttataa attctatgtt aagtaattct
    21961 agtgaaagct ttatagatgt atttgatgta aatacaatac atctaggatg cagtaaagaa
    22021 tgtaaatcta taaaaaaatg ttgtaagaga agggagaaat aatgatgaaa gtatgtatac
    22081 cagtagagga gaataaagga ttggatagta aaccatatgg acattttggt tctgctccaa
    22141 tttttgttgt gtgtgattta gaaagtggag aagttaaatc tttagataat ggagatttag
    22201 atcatgaaca tggaaaatgt caaccattaa aagcattgtc agggacagct gtagatgcag
    22261 tagttgttgg aggaatagga caaggagcta taattaaatt aaatggaatg ggaataaaag
    22321 tttacagagc agaaggtgat actataagtg ctaatttaga cttacttaaa aatggaaaat
    22381 tagtagaatt tccatcagac catacttgct cacatgacgg atgtgggcat cattaaaaaa
    22441 aacagctgat gaaatatata cttcatcagc tattttttct tttaataaat acgattttat
    22501 tcttttaaaa ccaaaattta gatttttatg ttttttgtag tatccttaat aatatttcaa
    22561 gtttacaagt ttactacttt tagatttttt tggtatgttt ttctatatag tcaatatcat
    22621 ttaatatgtc attgagttct ttattaagtg tttttaaatc atcaccatct acattgtagt
    22681 ttaaaaatag ttcctctaca ttatcaatga tagaattgac ctttctagta acttcaacaa
    22741 atgtcttaaa gttactacta tttttagcat ttagaaattt ttttaaatcc tttgatataa
    22801 atgatactat ttcatattca tcattaaata gacctctacc aataggatat ggttcaattc
    22861 tctgtaaaaa atattggtct ttagcattaa tattataagt ataagatatt tcccaaccgt
    22921 ctcctaaatc aaacttgata aaatataatg tactacttac ttttgatatt cttgtggcac
    22981 caagctgtct taaaagaact tcaatcgaat caccttgaac agtattaata ttcatatata
    23041 cacatcccct ttagtattat tatactatat tttttaaaat tttataatta aataaacagt
    23101 agatataata atggatataa tcataagtgg aaaacctatt ttgaaatact ccttaaaaga
    23161 gataggatga ccgtgtttat tacctatacc tgctagtaca acattagcag atgctcctat
    23221 tagtgttcca tttcctccaa gacaagctcc aagagatgtt gcccaccata gtggcattac
    23281 atcaatacct tcagcttgca tagtcaaaat aagaggaatt agtgttgcaa caaatggaat
    23341 attatctaag aaagaagaga ctatagctga caaccataat atcaacaaca ttgtaaatac
    23401 aagatgtcct tctgtaagtc caatcaatgc ttgagccaat ttgtttatta tcccaacttc
    23461 tactaatcca ccaactacta caaataatcc cataaagaat aaaattgtag accattcaat
    23521 acctgccata atttcatcta catcttgttt tcctattaaa agcattatag atgctcctgt
    23581 cagtgctaca acagaagaat ctatgtggat tgtactgtga aacataaaac caaaaagtat
    23641 gaatgctatt aatataaggc tttttataag tagaggttta tctttaacag attttttttc
    23701 atctagtttt aatattgcat ttttagctct ttcattcaca acaagttctt ttccataaat
    23761 aaatctaaag catattatag ttatagcaag tattactata acagcaggac ctaaatttat
    23821 tacaaaatcc ataaaactaa gattggcagc actaccaatc ataatatttg gagggtctcc
    23881 tataagagta gctgttcctc ctatatttga agctaaaatc tgtgttatta aaaatggaac
    23941 tggattaagt cctaatattt gtgtaataac tatagtcatt ggtccaataa gtaagacggt
    24001 tgtaacatta tctaatacag ctgataaaat agctgttata atagcaaagc aaatcattat
    24061 cttccatggg tcacctttgg ctttctttgc agtccagata gctatatatt caaataaccc
    24121 cgagtttttg acaacagcta caaatagcat cataccaact aatacaccaa tagtattgaa
    24181 atctatatgg cttaatcctt catcaagtgt aagtatattg aatattatca ttaatagtgc
    24241 accaccaaca gctgctacgg atctgtttac cttttctgta ataatagctg ccataactat
    24301 taaaaatata catatagcta ttatttgttg aaattccata atataagtac ctccatttgt
    24361 attattttgt gcctaatgct agtactatat atagtattac ttttttattg ttttttcaat
    24421 ggatgtatga aagtatatta tttaacaaag tttttgaaaa attgacagaa tttaaagaaa
    24481 atttttgcta tttaaataaa ttttaaaatt attccattga taataatatt aaacgacaaa
    24541 cgaaaaaata tac
//
LOCUS       DAMJXI010000053        24367 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.055, whole genome shotgun sequence.
ACCESSION   DAMJXI010000053 DAMJXI010000000
VERSION     DAMJXI010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24367
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.055"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(<1..122)
                     /locus_tag="PC465_002698"
     CDS             complement(<1..122)
                     /locus_tag="PC465_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2649984.1"
                     /translation="MEFFTAGVGVLKTLVTAIGAGLGAWGVINLMEGYGNDNPGA"
     gene            complement(124..435)
                     /locus_tag="PC465_002699"
     CDS             complement(124..435)
                     /locus_tag="PC465_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006740599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2649985.1"
                     /translation="MDREMININANLVKEAEFSEFEKDGENVKVANFALVKKYGKGKE
                     YTNCSVYGEKVEIVKEFEKGDLIHVFGYFKENKKGDKVYKNFIVKSLNKIENKKENEE
                     E"
     gene            complement(626..901)
                     /locus_tag="PC465_002700"
     CDS             complement(626..901)
                     /locus_tag="PC465_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2649986.1"
                     /translation="MYENRKSSLIILNINGEQFIMEIDTELTMDKKNYIEAICETMYD
                     ESNEWYEDIYDMSPYDIAELFEKTVKDEVGITVTFKAIDLEVSILED"
     gene            complement(920..2707)
                     /locus_tag="PC465_002701"
     CDS             complement(920..2707)
                     /locus_tag="PC465_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HDF2649987.1"
                     /translation="MLKAILSDIKNLIKIDNPKKFILSNIPYLSFFYIGNIFSKHINS
                     YVGGDIIDRLMVGISDIGTLSYIPSLNPRNLLVGISVAALVKLIVYSKGKNKKKYRQG
                     KEYGSARWGESKDIAPYIDPKFENNVLITNTERLTMNSRPKNPKYARNKNVLVIGGSG
                     SGKTRFYVKPNLMQMHSSYVVTDPKGTLVLECGKMLYENGYDIKILNTINFKKSMKYN
                     PFAYLRSEKDILKLVQTIIANTKGDGEKAGEDFWVKAEKLYYTALIGYIYYEAPEEEK
                     NFKTLLDMIDASEVREDDETYMNPIDRLFEALEKKDPSHFAVKQYKKYKLAAGKTAKS
                     ILISCGARLAPFDIRELRELMSEDELELDKIGDRKTALFVIISDTDDTFNFVVSIMYS
                     QLFNLLCDKADDVYGGRLPVHVRCLLDEFANIGLIPKFEKLIATIRSREISASIILQA
                     QSQLKAIYKDHADTIVGNCDSTLFLGGKEKTTVKELSETLGKETIDLYNTSETRSNQK
                     SFGLNYQKTGKELMSQDEITVMDGGKCIYQLRGVRPFLSDKFDITKHKNYKLLEDYDK
                     KNLFDVEEYLTNRDKVKLKSNYKINRLKI"
     gene            complement(2709..3443)
                     /locus_tag="PC465_002702"
     CDS             complement(2709..3443)
                     /locus_tag="PC465_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HDF2649988.1"
                     /translation="MISNLKTFENKNFGKLTVIEKDGEFFFIANEVAAMLGYVNPRKA
                     IYDHVDEEDKGVTKWNTPGGIQNISIINESGLYSLILSSKLPQAKIFKAWVTREVLPS
                     IRKNGGYIAGQEKKTNEELLADAILVANRIIAEREEEIEELRPKADYYDKLVDYNLLT
                     NFRNTAKELGIPQNQLISFLMDKGLIYRDKKKKLLPYADKNKGYFEVKEWVDPLGTLV
                     GIQTFITPKGRHYLLILLDSEGFYDE"
     gene            complement(3440..3925)
                     /locus_tag="PC465_002703"
     CDS             complement(3440..3925)
                     /locus_tag="PC465_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009431731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HDF2649989.1"
                     /translation="MINEEVSRSSLNLEVRLAKATSKAILDALKKVHKQIEEQGGLKN
                     VIKNNGEEVKLKDMVKKGQLEEINLKDPELKELKKILNKHGVKFSVMKDKETGNHSVF
                     FQSKDIKVMEHAFKKAVKASERKADRKDSITKTINKFKDMAKDTISKDKVKNKHKEQS
                     L"
     gene            complement(3918..4745)
                     /locus_tag="PC465_002704"
     CDS             complement(3918..4745)
                     /locus_tag="PC465_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2649990.1"
                     /translation="MKNLKDFVLRKNDIERNGHIYCKSCGKRVDGELVDLGFTKFIPR
                     IKCECEIKRDKENEERERLMKISSLKRDCFSSPLQHQYTFEKYLNEKDQAYKVAYNYA
                     KSFEQMKEDNVGLLFYGDVGSGKTYLACSIANELIERKQVKVKIMNLSQVINQIQKSA
                     FKLDSNEIINNLSNIPLLILDDLGIERDTSYAREQVYNIINSRYLKGRPTIFTTNLSL
                     EIIQNPNIDLEYQRIYSRILEMTIPVKVTGEDFRRKIHQEKLRKYKELLLYGGGIDD"
     gene            complement(4742..5515)
                     /locus_tag="PC465_002705"
     CDS             complement(4742..5515)
                     /locus_tag="PC465_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HDF2649991.1"
                     /translation="MNFDYFYNRQSEMYNFIRLPMVLMEDEIFESISIEAKVLYSYML
                     NRMGLSYKNGWIDEDGKVFIYYTIESIKDQFNCASEKANKLIAELDIKSGIGLIEKKR
                     QGLGKPNRIYVKDFMSIFNNMELKNQEVRKTKFQKFDNRNSRDSNIEIQDFRKSESNY
                     NNISNNELRNNDFSKGQKPYGIYKNIFLTDEDYKDLTNELGSRINEYIDRLSSYMKAN
                     NREYQDHKATIINWYLNDQAKNINDNTTRKMNYYIGESL"
     gene            complement(5745..7106)
                     /gene="rlmD"
                     /locus_tag="PC465_002706"
     CDS             complement(5745..7106)
                     /gene="rlmD"
                     /locus_tag="PC465_002706"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDF2649992.1"
                     /translation="MSVKKKDVIEFEVDKMEFGGTSLSQVGDRVIHMKGGISGQKVRA
                     GVKKVRSKKAEVKMIELLENSPLETEETCKHFRECGGCTLLSVPYEKQLEIKEKQVMD
                     LFLKQDLFGFQFLGIEGSPENKYYRNKMEYTFGDEVKNGPLTLGLHKKGKHIDIQTVE
                     ECMLVDEDFSKILVSSVEFFNEKKLPYYRTMNHKGYLRHLVVRKGIHTNEIMVNIVTS
                     SQEDFDMYEFKDMLLGIDLKSELVGVLHTINDGLADAVQCDELRVLYGRDYIQEEILG
                     LKFKISPFSFFQTNTKGAEVLYSIARDFIGDYNDKVVFDLYSGTGSIGQVMAGAAKKV
                     YGIEIVEEAVVAANENAKLNGLTNCEFIAGDVAKVVKDLKDKPDLIIVDPPRPGIHKD
                     AIRDICGFGAKEIVYISCNPKSLVVDLVDFKGYGYEIKMVKCMDMFPNTPHVETIALI
                     QKM"
     gene            complement(7133..7855)
                     /locus_tag="PC465_002707"
     CDS             complement(7133..7855)
                     /locus_tag="PC465_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDF2649993.1"
                     /translation="MAKKQRIDKILSNLGYGSRSEIKKYCKQGSVVVNGSEVSNPGTQ
                     VDTENDEILFNGEEVIYREYIYLMMNKPAGYISATTDKYDPTVLDLIDLSYLVFEPFP
                     VGRLDKDTEGLLVLTNDGKLSHRVLSPKKHVPKTYYAKIDGVVTEEDVEAFLEGVVLD
                     DGYKTMPSQLNILKSDDESEIELTIHEGKFHQVKRMFESVGKKVVYLKRLSMGNLKLD
                     ESLELGEYRELTDEEVKLIEER"
     gene            complement(7855..8184)
                     /locus_tag="PC465_002708"
     CDS             complement(7855..8184)
                     /locus_tag="PC465_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1904 domain-containing protein"
                     /protein_id="HDF2649994.1"
                     /translation="MPQIKIRGINENDICKISEKMINDLVEAVKCPRDYFEIECIKSV
                     AIRDGKIADVYPFVEVAWFDRGQEVQDIVARIITDSIRNNLDVESMDLAFTVFEKEKY
                     YENGEHF"
     gene            8514..9440
                     /gene="fba"
                     /locus_tag="PC465_002709"
     CDS             8514..9440
                     /gene="fba"
                     /locus_tag="PC465_002709"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-1,6-bisphosphate aldolase"
                     /protein_id="HDF2649995.1"
                     /translation="MALITTKEMFKKAYEGGFAIGAFNISDLEQLQGVLKAAKAKNSY
                     VMIQASMSAVKYAGPHTLVEMVKAASDEIGVDVALHLDHGPNMDAIKTCIDAGFSSVM
                     IDGSHFDFEENVRITKEAVEYAHSKGVVVEAELGVLAGTEDDVTSDVHKYTQPAEAVE
                     FVERTGVDSLAIAIGTSHGAFKFKGEAKLRFDILEEIQSKLPGFPIVLHGASAVDQNA
                     VATCNEFGGNIAGAKGVPVDMLRKASSMAVCKINMDTDLRLAMTAAIRKFLAENPKEF
                     DPRKYIGAGRDAIQAVVESKIDDVLGSANSIN"
     gene            complement(9575..11206)
                     /locus_tag="PC465_002710"
     CDS             complement(9575..11206)
                     /locus_tag="PC465_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2649996.1"
                     /translation="MDNNLIGLIEHVENPAILCKESGEIIYCNHLIDSIFSFLDIKKP
                     RNINELDSNFDKTEILTDSKKKIAFRELRMTAHIYNMKDNNNENNIVYLFEKSLISDK
                     VIEDIIEHIDEVVVVFNKDGVIEKMNTVSDEILPFKRTEVLGRNITDLVRQGLVEEPI
                     ILNMLKVKKKIYRNIVYPDGKLIAYTAVPRWDSKGKLTGGVLTGRDISRVIKLESQIK
                     YSDISEDTEYISQSKIMDNIKKVVKRAAASDSSIFINGESGVGKEIIARTIYKYSSRR
                     DKPFIAINCGAIPNELLESEFFGYEEGSFTGAKKKGKKGLFEEANGGTIFLDEIGELP
                     MQMQKKLLRVIQENTITRIGGSKPIKIDVRYISATNISHEDLRNNLKFRQDLYYRLSV
                     IPVKIPPLRERKEDIVPLVNYFLKLYNEKYNREVEVSPKVIELLEEYSWPGNIRELKN
                     IIERFVVLSAKNVIGEDEFNMLINLDMIDNETDDLSPIVVNGIMNLNDAYKIVDQIMI
                     SKAINKYGSITKAAEVIGIYPSTIHRKIKSGHIHV"
     gene            complement(11689..12726)
                     /locus_tag="PC465_002711"
     CDS             complement(11689..12726)
                     /locus_tag="PC465_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDF2649997.1"
                     /translation="MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDA
                     ELCAILLGKDVDGLAKELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIM
                     LFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
                     HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDA
                     NVIVSGGLGLGGPEGFEMLKKLADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPN
                     LYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVGDLHEIVPMLIEKLD
                     SVDDLLEAIKA"
     gene            complement(12745..13530)
                     /locus_tag="PC465_002712"
     CDS             complement(12745..13530)
                     /locus_tag="PC465_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012703997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF2649998.1"
                     /translation="MKILVCVKQVPDTNEVRINKETGTLIRDGVPSILNPDDANALEE
                     ALKIKDEHDDVTITVITMGPPQADFMLRECLAMGADDAILLSDRAFGGADTWATSNTI
                     AAGISKVGDYDIIFAGRQAIDGDTAQVGPQIAEKLDIPQVTYVQDFKIEGKDIIVQRQ
                     LEDGYELIKVSTPVLLTAVKELNTPRYMSVDKIVKAYKHDVKVWTIDDLDVNKEEVGL
                     KASPTKVFRSFTPEPRGKGEILEGKADEIASKIIIGLKQKHII"
     gene            complement(13563..14696)
                     /locus_tag="PC465_002713"
     CDS             complement(13563..14696)
                     /locus_tag="PC465_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HDF2649999.1"
                     /translation="MLYNKEQELLRKAVRDFVSKELDTLPAEMDKTGVMPKELIKKLA
                     DAKFISSNIPEEYGGGGAGYVSYAIVMEEIARRCASTATFVTAGSSLASLPILYNGTE
                     EQKQKYLKGIATGELIGAFGLTEPGAGSDAGGQQTTAELVGDHYILNGRKTFITNGPF
                     CDVAIVIAVTDRSKGLRGTSAFIVESKWDGFSTGAHEDKMGIRGTETSDLIFENVKVP
                     KENLLGKEGQGFKIAMGTLEVGRIGVAALALGIAQGALDEAVKYTKQRVQFGKPIAKF
                     QNTQFTIADMETKVCAARGLVYDAAQKRDAGMRVAQESAMAKYYASEIANEVAYKALQ
                     LHGGYGFIKDYEIERMYRDARIVSIYEGTSEVQKMVISSNVLK"
     gene            complement(14744..15871)
                     /gene="hadC"
                     /locus_tag="PC465_002714"
     CDS             complement(14744..15871)
                     /gene="hadC"
                     /locus_tag="PC465_002714"
                     /EC_number="4.2.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     beta"
                     /protein_id="HDF2650000.1"
                     /translation="MEAILSKMKEVVENPNAAVKKYKSETGKKAIGCFPVYCPEEIIH
                     AAGMLPVGIWGGQTELDLAKQYFPAFACSIMQSCLEYGLKGAYDELSGVIIPGMCDTL
                     ICLGQNWKSAVPHIKYISLVHPQNRKLEAGVKYLISEYKGVKRELEEICGYEIEEAKI
                     HESIEVYNEHRKTMRDFVEVAYKHSNTIKPSIRSLVIKSGFFMRKEEHTELVKDLIAK
                     LNAMPEEVCSGKKVLLTGILADSKDILDILEDNNISVVADDLAQETRQFRTDVPAGDD
                     ALERLARQWSNIEGCSLAYDPKKKRGSLIVDEVKKKDIDGVIFCMMKFCDPEEYDYPL
                     VRKDIEDSGIPTLYVEIDQQTQNNEQARTRIQTFAEMMSLA"
     gene            complement(15871..17097)
                     /gene="hadB"
                     /locus_tag="PC465_002715"
     CDS             complement(15871..17097)
                     /gene="hadB"
                     /locus_tag="PC465_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     HadB"
                     /protein_id="HDF2650001.1"
                     /translation="MSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELA
                     EVFDLNVLYPENQAAGVAAKKGSLELCEIAESKGYSIDLCAYARTNFGLLENGGCEAL
                     DMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQF
                     EEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYM
                     AVIVCARGKKETTEAFKLLIEELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMK
                     TLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLVEGK
                     CDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQG
                     LVEVMEERKKLNRGEI"
     gene            complement(17112..17912)
                     /gene="hadI"
                     /locus_tag="PC465_002716"
     CDS             complement(17112..17912)
                     /gene="hadI"
                     /locus_tag="PC465_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyisocaproyl-CoA dehydratase activator
                     HadI"
                     /protein_id="HDF2650002.1"
                     /translation="MYTMGLDIGSTASKGVILKNGEDIVASETISSGTGTTGPSRVLE
                     KLYGKTGLAREDIKKVVVTGYGRMNYSDADKQISELSCHARGVNFIIPETRTIIDIGG
                     QDAKVLKLDNNGRLLNFLMNDKCAAGTGRFLDVMAKIIEVDVSELGSISMNSQNEVSI
                     SSTCTVFAESEVISHLSENAKIEDIVAGIHTSVAKRVSSLVKRIGVQRNVVMVGGVAR
                     NSGIVRAMAREINTEIIVPDIPQLTGALGAALYAFDEAKESQKEVKNI"
     gene            complement(17951..19150)
                     /gene="hadA"
                     /locus_tag="PC465_002717"
     CDS             complement(17951..19150)
                     /gene="hadA"
                     /locus_tag="PC465_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocaprenoyl-CoA:2-hydroxyisocaproate
                     CoA-transferase HadA"
                     /protein_id="HDF2650003.1"
                     /translation="MLLEGVKVVELSSFIAAPCCAKMLGDWGAEVIKIEPIEGDGIRV
                     MGGTFKSPASDDENPMFELENGNKKGVSINVKSKEGVEILHKLLSEADIFVTNVRVQA
                     LEKMGIAYDQIKDKYPGLIFSQILGYGEKGPLKDKPGFDYTAYFARGGVSQSVMEKGT
                     SPANTAAGFGDHYAGLALAAGSLAALHKKAQTGKGERVTVSLFHTAIYGMGTMITTAQ
                     YGNEMPLSRENPNSPLMTTYKCKDGRWIQLALIQYNKWLGKFCKVINREYILEDDRYN
                     NIDSMVNHVEDLVKIVGEAMLEKTLDEWSALLEEADLPFEKIQSCEDLLDDEQAWAND
                     FLFKKTYDSGNTGVLVNTPVMFRNEGIKEYTPAPKVGQHTVEVLKSLGYDEEKINNFK
                     DSKVVRY"
     gene            19827..20825
                     /locus_tag="PC465_002718"
     CDS             19827..20825
                     /locus_tag="PC465_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HDF2650004.1"
                     /translation="MKILVFGARDYEEPVIKKWSEEHKDVQVDIYPENMTEENVVKAK
                     GYDGISIQQTNYIDNPYIYETLKDAGVKVIASRTAGVDMIHFDLVNENGLIVTNVPSY
                     SPNAIAELAVTQAMNLLRKTPLVKKKVCEGDYRWIAELLGTEVRSITVGVIGTGKIGA
                     TSAKLFKGLGANVIAFDQYPNSDLNDILTYKDSLEDLLKEADLITLHTPLLEGTKHMI
                     NKDTLAIMKDGAYIVNTGRGGLINTGDLIEALESGKIRAAALDTFETEGLFLNKKMNP
                     GELTDPEINKLLSMEQVIFTHHLGFFTSTAIENIVYSSLSSAVEVIKTGTATNRVN"
     gene            21187..21714
                     /locus_tag="PC465_002719"
     CDS             21187..21714
                     /locus_tag="PC465_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04002 family protein"
                     /protein_id="HDF2650005.1"
                     /translation="MEKMNKVTSKKTTYIVTSALFASIICLTIAYILHIPVGGNNGYV
                     HIGDAFIYLAATILPTNYAIAASAIGAGLADLSTGAAIWVIPTIIIKPILVLFFTSKS
                     DKIINKRNIVASVVAGIVGLVLYMFAEGIIIGSFTSAFVMSLLGLLQPIGSFIVFIIL
                     GMALDKLDFKKRYFN"
     gene            21741..22337
                     /locus_tag="PC465_002720"
     CDS             21741..22337
                     /locus_tag="PC465_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04100 family radical SAM protein"
                     /protein_id="HDF2650006.1"
                     /translation="MNILYTIENSIYVNITNTCPCSCVFCIRNEKDEVANSGSLWLEH
                     EPSVDEVKEAFNKYNLDDYDEIVFCGYGEPLMRINELIEVAKFIKEKSSIKIRINTNG
                     LSDLIHNKKTAILLKNVIDAVSISLNAPNKEAYNRVTQPKFGEKSFDYMLDFAKDCKK
                     YIKEVAFSVVDEISPEEIEESKQLAKKLDIPLRVRHKN"
     gene            complement(22416..23999)
                     /gene="asnB"
                     /locus_tag="PC465_002721"
     CDS             complement(22416..23999)
                     /gene="asnB"
                     /locus_tag="PC465_002721"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HDF2650007.1"
                     /translation="MINLEEKYLTRKDTYMIKILEYNGHIRNWKVLCEELGIDSSLCR
                     DERERAILVEAYKTWGYDMANHMHGMFAFALWDTVEKKLFCLRDQFGVKPFYYYETEN
                     GKLLYGSSIRKIMEQPGFVKELNEDMLQIYMSFTYVAGENTFFRGVKKLMPGHYLVYQ
                     NKTVCIGRYWKPEFHPDHSKSIEEWTDEIHTTLQKIMPEVKSENETAELFLSGGVDSS
                     YILAMSDIEKTGSCGYEEERFDESKLAQQTANILGCKNSRYIITPEEYFASVPYVMYH
                     MEQPTGDASAIVFAIGCKAAAENTNICYSGEGADEFFGGYNIYHKAECYGENLKTFYI
                     GNTNIMNEGEKRKILKKYNPDVLPIEVVKGIYEETEELDTLTNMSNVDIQIWLEGDIY
                     FNIDKMSTAVGLEVRMPLTDTRIFDIASRIPSEYKVKGKENKIAFRTAASKTLPEEIA
                     FRNKLGFIVPIRIWMADDQYNKDIRDKFNSEIADKFFNIDEINEIFNDYISGNSDNWR
                     KIWMIYTFLVWYEIYFVKC"
BASE COUNT         7415 a         4477 c         2965 g         9510 t
ORIGIN      
        1 gcaccagggt tatcattacc ataaccttcc attaagttaa taactcccca tgctcctaaa
       61 cctgcaccaa ttgcagttac aagtgttttt aaaactccaa ctccagctgt aaaaaattcc
      121 atattattcc tcctcgtttt ctttcttatt ttctattttg tttagtgatt taactataaa
      181 attcttgtag accttatctc cttttttgtt ttctttgaaa tatccaaaga cgtggattag
      241 atctcctttt tcaaattctt ttacaatttc taccttttct ccatatactg agcaatttgt
      301 atattctttg ccctttccat attttttaac aagagcaaaa tttgctactt taacattttc
      361 tccatccttt tcaaattctg aaaattcagc ttccttaact aaatttgcat taatatttat
      421 catttctcta tccattaatt ttttctcctt aatctataaa tttcaattaa aaaagcgact
      481 gaacttatat ttcaaccgct aaatgtctta tatattaaat tgttttaagt aggacttctt
      541 atccttacca ttttaacctc ctaattttgt gtataaaaaa aggcgataga gtttttaatt
      601 tctatcgcct attaacacat tatttctagt cttctaaaat cgatacttca aggtctatcg
      661 ctttaaatgt aacagttatt cctacttcgt cctttactgt tttttcaaat agctcagcta
      721 tatcatatgg ggacatatca tatatatctt cataccattc attactttca tcgtacattg
      781 tctcacatat tgcttcaata taatttttct tatccattgt gagttctgta tcaatttcca
      841 taataaactg ctcaccattt atatttaata taattaaaga tgattttcta ttttcataca
      901 ttttgctttc tccataaact caaattttta gcctatttat tttataattt gattttaact
      961 ttaccttatc tctatttgtt agatactctt ccacatcaaa caagtttttc ttatcataat
     1021 cttccaacaa cttgtaattc ttatgctttg taatatcaaa tttatctgac aagaaaggtc
     1081 ttactcctct tagttggtat atgcactttc caccatccat tacagttatt tcatcttggc
     1141 tcataagttc cttgccagtt ttttggtaat ttagtccaaa agatttttga tttgatcttg
     1201 tttctgatgt gttatatagg tctatggttt cttttcctaa ggtttctgat aattctttta
     1261 ctgttgtttt ttcttttcct cctagaaaaa gtgtagagtc gcagttacca actattgtat
     1321 ctgcatggtc tttatagatt gcttttaatt gagattgtgc ttgtaatatt atgcttgctg
     1381 atatttctct tgaacgaatt gtcgctatta gtttctcaaa ttttggaatt aagcctatat
     1441 ttgcaaactc atcaagtaga cacctaacat gaactggaag tcttccacca tatacatcat
     1501 ctgccttatc acatagtaga ttaaataatt gagaatacat tattgaaact acaaaattaa
     1561 atgtatcatc tgtatctgat attattacga acaaggcagt tttcctatct ccaattttat
     1621 cgagttctaa ttcgtcttcg ctcattagtt ctctaagctc tcttatatca aaaggtgcaa
     1681 gccttgctcc acaagatatt agaattgact tggcagtttt tcctgctgcc agtttatatt
     1741 tcttatattg cttaactgca aaatgacttg gatctttctt ttcaagagct tcaaagagcc
     1801 tatcaattgg gttcatatag gtttcgtcat cttctctaac ctcacttgcg tcaatcatat
     1861 ctaagagtgt tttaaaattc ttttcttctt caggtgcttc ataataaata taaccgatga
     1921 gggcagtgta atataacttc tcagccttta cccagaaatc ttctcctgcc ttttctccat
     1981 ctccctttgt gttagcaatg attgtttgca caagttttaa aatatctttt tctgatcgaa
     2041 gataagcaaa tggattgtat ttcatagact ttttaaagtt tattgtgttc aaaatcttta
     2101 tgtcatatcc attttcatat aacatttttc cacactctaa tacaagtgtc cccttagggt
     2161 ctgttactac ataagaagag tgcatttgca ttagatttgg ctttacataa aatcttgttt
     2221 tacctgatcc agaacctcct attactaata catttttatt tctagcgtat ttagggtttt
     2281 taggtcttga gttcattgta agtctttcgg tattagttat aagaacatta ttttcaaact
     2341 ttggatcaat atatggagca atatccttac tttctcccca tcttgcagat ccatattcct
     2401 tgccttgcct atatttcttt ttatttttac ctttgctata aacaattagc ttaacaagag
     2461 cggcaactga aatacccact aacaagttcc ttggattaag gcttggtata taagataaag
     2521 ttcctatatc agaaattccc accattaatc tatcaataat atctcctcca acataagaat
     2581 tgatgtgctt agaaaagata tttccaatgt agaaaaagga taaataagga atgtttgata
     2641 atataaattt ctttggattg tctattttaa ttaggttttt aatatcagaa agaatggctt
     2701 ttaatatctt attcatcgta gaaaccttca ctatctaata aaattagtag gtaatgcctt
     2761 ccctttggtg ttataaatgt ctgtatgcct acaagtgtac caagtggatc aacccattct
     2821 tttacttcaa aatatccctt gttcttatct gcataaggta gaagtttctt tttcttatct
     2881 ctgtaaatta atcccttatc cattagaaaa cttatcaact gattttgtgg tattcctaac
     2941 tctttggcag tatttctaaa gtttgtaagt aggttataat ctactaattt gtcataatag
     3001 tctgcctttg gtcttaattc ttcaatctct tcttctcttt cggcaataat tctattggca
     3061 accagaattg catctgcaag tagctcttcg ttagttttct tttcttgacc agctatatat
     3121 cctccatttt ttctaatact tggtaagact tctctagtta cccaagcttt gaatattttt
     3181 gcttgtggta gttttgatga gaggataagt gaatacaatc ctgactcatt aattattgaa
     3241 atattctgta ttcctccagg ggtgttccat ttcgttacac ccttatcttc ttcatctaca
     3301 tggtcataaa tagcttttct tggattgaca tatcctagca tagctgctac ttcatttgct
     3361 ataaagaaaa actcaccgtc tttttctata acagtgagtt tcccaaaatt cttattttca
     3421 aatgttttta aattacttat cataagcttt gctccttatg tttattttta actttatctt
     3481 tactaattgt gtccttagcc atatctttaa acttatttat tgtcttcgtt atcgaatctt
     3541 ttctatcggc ctttctttca gaagccttaa ctgctttttt aaaggcgtgt tccataactt
     3601 ttatatcctt agattgaaaa aacacagagt ggttgccagt ttctttatct ttcataacag
     3661 aaaacttcac tccgtgttta tttaaaattt tctttagttc ttttaactca ggatctttta
     3721 gattaatttc ttctaactgt ccctttttaa ccatgtcctt tagttttact tcttctccgt
     3781 tattttttat tacatttttc aagcctcctt gttcttctat ttgcttgtgt actttcttta
     3841 aggcatcaag aattgcttta cttgttgctt ttgcaagtct tacttcaagg ttaagactcg
     3901 acctagatac ttcttcatta atcatctatt ccacctccat ataaaagtaa ctctttgtat
     3961 tttcttaact tctcttgatg tatttttctt ctaaaatctt ctcccgtaac tttaactggt
     4021 attgtcattt caagtattct tgaatatatc ctctgatact caaggtcaat attaggattt
     4081 tgaataattt ccaatgataa gtttgtagta aaaattgtcg gcctaccctt taagtatctt
     4141 gagtttataa tgttgtatac ttgttctctt gcataagatg tatccctttc aattccaaga
     4201 tcatctaaaa ttaacaacgg aatattagag aggttattga taatttcatt tgaatctagc
     4261 ttaaatgctg atttttgtat ttggtttata acctgagata aattcataat cttaacttta
     4321 acttgctttc tttcgattaa ttcatttgca atagaacaag caagataagt ctttccactg
     4381 ccaacatctc cataaaataa aagtccaaca ttgtcttctt tcatttgttc aaagcttttg
     4441 gcataattat aagcaacctt ataggcttga tctttttcat ttaagtattt ctcaaaagta
     4501 tattggtgct ggagcggcga tgagaagcaa tctcttttca atgacgatat tttcatcagt
     4561 ctttctcttt cttcattttc cttatctctt tttatttcac attcacattt aattcttgga
     4621 ataaactttg taaatccaag atcaactaat tctccatcga ctcttttacc acatgattta
     4681 caataaatat gtccatttct ctcaatatca ttttttctta atacaaaatc ttttaagttc
     4741 ttcataaact ctctcctata tagtaattca tttttcttgt tgtattatca ttaatgtttt
     4801 ttgcctgatc attaagatac caattgatta tcgttgcctt gtgatcttga tactctctgt
     4861 tatttgcttt catatatgac gagagcctat caatgtattc attaattcta cttcctaact
     4921 catttgttaa atccttgtaa tcttcatcag tcaaaaatat atttttatat attccataag
     4981 gcttttgtcc cttactaaaa tcattatttc ttaactcatt attactaata ttgttatagt
     5041 tactttccga ttttcgaaaa tcttgaattt cgatattcga atctcttgaa tttcgattat
     5101 cgaacttctg gaattttgtt tttcgaactt cttgattttt taattccata ttattaaata
     5161 tgctcataaa gtctttaaca taaattctgt taggctttcc aagtccttgt cttttctttt
     5221 caatcagtcc tattcctgat ttaatatcaa gctcagctat taatttattt gctttttcac
     5281 ttgcacaatt aaattgatct tttatacttt caattgtgta gtaaataaag acttttccgt
     5341 cttcatctat ccagccattt ttatatgaaa gacccattcg attaagcata tatgaataca
     5401 aaactttagc ttcaatagaa atgctctcaa aaatttcatc ttccattaat accataggta
     5461 acctaatgaa gttatacatt tcagattgcc tattataaaa ataatcaaaa ttcatcccta
     5521 cctcctttct ttgaattaaa aaagagtagc cttatttaag ctactcttgt agaaagtata
     5581 aaatgggttt tttcttatta tatttttctt tgtgtctcct cataccagtt gcaaaactac
     5641 tcttacgtcc atgtagtttt tttgggtctt tttgacgtat ccttcttcat ctttatcgaa
     5701 gacaaaatgc ttataaaact gcttaaaatg caggatttct aaatttacat cttttgtatc
     5761 aacgctatag tctccacgtg tggcgtattt gggaacatat ccatacactt aaccatctta
     5821 atctcataac catacccctt aaaatcaacc aaatcaacaa ccaaagactt aggattacaa
     5881 gaaatataaa caatctcctt agcaccaaat ccacaaatat ccctaatagc atccttatga
     5941 atgcctggtc taggagggtc aacaataatc aaatcaggct tgtcctttaa atccttaaca
     6001 accttagcca catccccagc aataaactca caattagtaa gtccattcaa cttagcgttc
     6061 tcattagcag caacaacagc ttcctcaact atctcaatac catacacttt cttagcagca
     6121 ccagccataa cctgtccaat agacccagta ccactataca agtcaaatac aactttatca
     6181 ttgtaatctc caataaaatc cctagcaata ctataaagaa cctcagctcc cttagtattg
     6241 gtttggaaaa acgaaaatgg tgaaatctta aacttaagac ctaaaatttc ttcttgtata
     6301 taatctcttc catacaatac tcttaactca tcacattgga ctgcatctgc taaaccatca
     6361 ttaatagtat gaagtactcc caccaactca gattttaaat caatccctaa aagcatatct
     6421 ttaaactcat acatatcaaa atcttcttga gaagaagtta ctatattaac cataatctca
     6481 ttagtgtgaa tcccttttct aactacaaga tgtctcaaat atcctttgtg attcattgtt
     6541 ctataataag gaagcttttt ttcattgaaa aactctacac tagaaactaa tatctttgag
     6601 aagtcttcat caaccaacat acactcctca acagtttgta tatctatatg ctttcctttt
     6661 ttatgaagac ctaatgtcaa aggtccattt tttacttcat ctccaaaagt atattccatc
     6721 ttatttctat aatatttgtt ttctggactt ccttctatcc ctaaaaactg aaatccaaat
     6781 aaatcttgct ttaaaaataa atccataact tgtttttctt ttatttctaa ttgtttttca
     6841 tatggcacag acaatagtgt acatcctcca cactctctaa agtgcttgca agtttcttca
     6901 gtttcaagtg gtgagttctc taataattct atcatcttaa cttcagcttt cttacttcta
     6961 acttttttaa ctccagctct caccttttga ccacttattc cacccttcat atggataact
     7021 ctatctccaa cttggcttaa agatgtacca ccaaattcca ttttatctac ttcaaattct
     7081 ataacatctt ttttcttcac agacattcct ccaatttact atagtatctt tattatcttt
     7141 cttcaatcaa ttttacttct tcatctgtta actctctata ctcacctaac tctaaacttt
     7201 catccaattt taaattgccc atagacaatc tttttaagta tactactttt ttgcctacgc
     7261 tttcaaacat tctttttact tggtgaaact taccttcatg tattgtaagc tctatttctg
     7321 attcatcatc actttttaat atatttaact gtgatggcat agttttatat ccgtcatcaa
     7381 gcactacacc ttctaaaaaa gcttctacat cttcttcagt aactactcca tcaatttttg
     7441 cataataagt cttaggcaca tgcttcttag gagataaaac tctatgagaa agctttccat
     7501 cattagtcaa aactaataat ccctctgtgt ctttatctaa ccttccaaca ggaaatggtt
     7561 caaaaactaa gtatgataaa tcaattaaat ctaatactgt tgggtcatat ttatctgtag
     7621 ttgctgatat atatccagca ggtttattca tcatcaaata tatatattct ctatatataa
     7681 cttcttctcc attaaataat atctcatcat tttcagtgtc tacttgagtt cctggatttg
     7741 aaacttcact tccatttact actacagacc cttgtttaca atacttcttt atttcacttc
     7801 tgcttccata acctaaattt gaaagaattt tatctatacg ttgcttttta gccattaaaa
     7861 atgctctcca ttctcataat atttttcttt ttcaaatact gtaaatgcta aatccatact
     7921 ttctacatct aaattatttc ttatactatc agttattatt cttgctacta tatcttgtac
     7981 ttcttgtcct ctatcaaacc aagctacttc aacaaaagga tatacatctg ctattttacc
     8041 atctcttatt gcaactgact ttatacattc tatttcaaag tagtctcttg gacattttac
     8101 agcttcaact aaatcattta tcattttttc acttatttta catatatcat tttcattaat
     8161 tcctcttatt tttatctgtg gcatagttta tctcctttat tttaaatttt tagtgaatta
     8221 tcatccactt aattcccttc gataacgttt gaagtggcaa cttcttggtc aagacaacta
     8281 ttgttatcag tatctccaaa ctaataaggt agttcctacc cttatagtta gcattatata
     8341 gctaattttc ctaaattgtt tatattcttt attattttat ttaatcctat tgtcttctat
     8401 ttaacattat acttgtaatt tatagttatt acaatttact atgtactttt tttgatttaa
     8461 cgttataata taagtgatgg gtaaatttta aaagttaata ggaggagttt aaaatggcat
     8521 taattactac aaaagaaatg tttaaaaaag cttacgaagg tggatttgct ataggtgcat
     8581 ttaacataag tgacttagaa caattacaag gtgttttaaa agctgctaaa gctaaaaatt
     8641 cttatgttat gatacaagct tctatgtcag ctgttaaata tgctggacct catacattag
     8701 ttgaaatggt taaggctgct tctgatgaaa taggtgtaga tgtagctctt cacttagacc
     8761 atggtccaaa tatggatgct attaaaactt gtattgatgc tggtttctct tcagttatga
     8821 tagatggttc tcattttgac tttgaagaaa atgttagaat aactaaagaa gctgttgaat
     8881 atgcacactc taaaggtgtt gttgttgaag cagaacttgg tgttctagct ggaacagaag
     8941 atgatgttac ttctgatgtt cacaagtata ctcaaccagc tgaggcagtt gagttcgttg
     9001 aaagaacagg tgttgattca ttagcaatag ctattggaac ttctcatggt gctttcaaat
     9061 tcaaaggaga agctaaatta agattcgata tactagaaga aatccaaagc aaattaccag
     9121 gtttcccaat agttcttcat ggtgcatctg ctgttgacca aaatgctgtt gctacatgta
     9181 atgaatttgg tggaaatata gctggtgcta aaggtgtacc tgtagatatg ttaagaaaag
     9241 catcttctat ggctgtttgt aaaataaaca tggatactga cttaagacta gctatgactg
     9301 ctgctatcag aaaattctta gctgaaaatc caaaagaatt tgacccaaga aaatacattg
     9361 gtgctggtag agatgctata caagctgtag ttgaaagcaa gatagatgat gttttaggtt
     9421 ctgctaactc tataaactaa tataactttt aaatatttat aaaagaaaag agatgactta
     9481 aagtaattaa atttattttt aagccatctc ttttaagttg tataaattat gtatcttata
     9541 atattttaat tatattgtct ttttaaactg acagctaaac gtgaatatgt ccactcttta
     9601 tctttctatg gatggtagaa ggatatatac ctataacttc agcagccttt gttattgaac
     9661 catacttatt tatagcctta cttatcatta tttggtccac tattttatat gcatcattaa
     9721 gattcataat tccatttacc actattggtg ataaatcatc tgtttcatta tcaatcatat
     9781 ctaaatttat cagcatgtta aattcatctt ctccaattac atttttagct gataatacta
     9841 caaatctttc aatgatgttt tttaattctc ttatgtttcc tggccaagaa tattcttcta
     9901 ataactcaat aactttaggc gaaacttcta cttctctatt gtacttttca ttgtaaagtt
     9961 ttaagaaata atttactaat ggtactatat cctcttttct ttctctaaga ggaggtattt
    10021 ttactggaat aacacttaat ctatagtaca aatcttgtct aaatttaagg ttatttctaa
    10081 ggtcttcatg agaaatatta gtagcactta tatatctaac atctattttt ataggcttac
    10141 taccacctat tctagtaata gtattttctt gtataaccct aagtaatttt ttttgcatct
    10201 gcattggtaa ctcacctatc tcatccaaga aaatagttcc accattcgcc tcttcaaaaa
    10261 gtcccttttt accttttttc ttagctccag taaaagaacc ttcttcatat ccaaaaaact
    10321 ctgactctaa taattcattt ggtatagctc cacagtttat agctataaaa ggtttgtctc
    10381 tccttgaact atacttatat attgttcttg ctattatttc ttttcctaca cctgattctc
    10441 catttataaa tatagaagaa tctgaggctg cagctctctt aacaactttt tttatattgt
    10501 ccataatctt actttgactt atatactctg tgtcttctga tatatcacta tattttatct
    10561 gagattcaag cttaataacc cttgaaatat ctctccctgt tagtactcct cctgtaagct
    10621 ttcccttaga atcccatctt ggaactgccg tatatgcaat aagcttccca tctgggtaaa
    10681 cgatatttct ataaatcttt ttcttcactt taagcatgtt taatattatt ggttcttcaa
    10741 ctaatccttg tctcacaagg tctgttatat ttctaccaag tacctcagtt cttttaaaag
    10801 gtaatatctc atcactgaca gtgttcatct tttcaattac cccatctttg ttaaacacaa
    10861 caacaacttc atctatatgc tctattatat cttcaattac tttatcagat attagagact
    10921 tctcaaataa ataaactata ttattttcat tattattatc tttcatattg tatatatgtg
    10981 cagtcatcct taactctctg aaagctattt tctttttact atctgtcagt atttctgttt
    11041 tgtcaaaatt tgaatctaat tcatttatat ttctaggctt ttttatatct agaaaactaa
    11101 aaatactatc tattagatga ttacagtata ttatttcgcc tgattcttta cataaaatgg
    11161 ctggattttc tacatgttct ataagcccta ttaaattatt atccattaat attcgcacct
    11221 ttcattaagt aatttattga actacataca aaatttattg tttgcttaca ataaatacca
    11281 tcagcacata taatcaactc cttataatat tcgtcttttc aagtagttta tttcattaaa
    11341 acgtaactaa gatataattt taatgattat agtttgttaa aaatttcatt ttgcttttaa
    11401 ttgtatttta tcacatattt agtaattatt tgtctattta atacaattta attaaattta
    11461 agatttattt aaaaaaacaa agataatcct tacagaatat aactcacaat ttgtaagcaa
    11521 tatacatata aggattatcc agattatctt gtattataaa attttattca aacagacttt
    11581 ttaataactg acaaatacac actagcaata acttatcaaa gggttaataa ttatgttact
    11641 aactaataag acttattcaa tcagtaatat ttatatagtt tgtatctatt aagcttttat
    11701 agcttctaat aaatcatcaa cactatctaa tttttctata agcattggaa ctatttcatg
    11761 taagtctcca actactccat agtcagcgat ttctaaaatt ggagctgctg ggtttttgtt
    11821 tatagcaatt atgaaatctg atgattgcat acctgctaaa tgttgtattg ctcctgatat
    11881 accacaagct atatataggt ttggtttaac agtagttcct gtttgaccta cttggtgaga
    11941 atggtctatc catccagcat caacagccgc acgagaagaa ccaactactc cacctaattt
    12001 gtcagctaat ttcttaagca tttcaaatcc ttctggtcca cctaatccta aaccacctga
    12061 tactataaca tttgcatctg taagagatac taaatctttc ttagttttaa ctgtttctaa
    12121 aacagtagtt cttatatcat cttgagttat tttgtagtct aatgctataa cttcaccagt
    12181 tcttgtttcg tctttttcag ctttatccat aacaccaggt ctaactgtag acatttgagg
    12241 tctatggttt ggacaaatga ttgtagccat tatgtttcca ccaaatgctg gacgagtttg
    12301 ttttattttc ttatcttctg ggtctatttc taacttagta cagtcagctg ttaatccagt
    12361 tccaactctt gaagctattc taggtgctaa gtctctacct atatgagttg ctccgaaaag
    12421 cattatttct ggttttattt catctattgc atcttttatt acttttgtat atgcatcagt
    12481 tgtatatttt tctaaaagag catcatctgc aacataaact ttgtcagctc caaaagtgat
    12541 taattcttta gctaatccat caacatcttt tcctaataat attgcacaaa gttctgcatc
    12601 tacttcttta gctaattttc ttccttctcc taataattct ataactactg gagctatttt
    12661 tccttctctt tgttctgcaa atatccatac gtttttataa gaacttaaat cttttatatc
    12721 attcatagtt tgtactcctc caacttatat aatgtgcttt tgttttagac cgattattat
    12781 tttactagct atttcatcag ctttaccttc taagatttct ccttttcctc ttggttcagg
    12841 agtaaatgat ctaaatactt tagttggtga tgcttttaaa ccaacttctt ctttatttac
    12901 atctaaatca tcaattgtcc aaacttttac atcatgttta tatgctttta ctattttatc
    12961 aacagacatg tatctaggtg tatttaactc ttttactgct gttaaaagta caggtgtact
    13021 tacttttatt aattcgtatc catcttctaa ttgtctttga actattatat cttttccttc
    13081 tattttgaaa tcttgtacat atgtaacttg aggaatgtct aatttctctg caatttgtgg
    13141 tccaacttgt gcagtatctc catctattgc ttgtcttcct gcaaatatta tgtcatagtc
    13201 acctacttta gatattcccg ctgcaatagt atttgatgta gcccaagtat cagctcctcc
    13261 aaatgctcta tcacttaata atattgcatc atcagcaccc atagctaaac actctcttag
    13321 cataaagtct gcttgaggag gtcccattgt tataactgtt atagttacat catcatgctc
    13381 atctttaatt tttaaagctt cctctaatgc atttgcatca tctgggttta atatacttgg
    13441 aactccatct cttataagag tacctgtttc tttatttatt cttacttcgt tagtatctgg
    13501 aacttgtttt acgcaaacta atattttcaa agtctatacc tccaatttca ttagattatt
    13561 tattatttta atacgtttga tgaaattacc attttttgaa cttctgatgt tccttcgtat
    13621 attgatacga ttctagcatc tctgtacatt ctttcgattt cataatcttt tataaatcca
    13681 tatccaccgt gaagttgtaa tgctttataa gcaacttcat ttgcaatttc tgatgcatag
    13741 tatttagcca tagcagattc ttgagcaact ctcattcctg catctctctt ttgtgctgca
    13801 tcataaacta atcctctagc tgcacaaact tttgtttcca tgtcagctat agtaaattga
    13861 gtattttgga atttagctat aggcttacca aattgaactc tttgttttgt atatttaaca
    13921 gcttcatcta aagcaccttg agctattcct agagctaagg cagcaacacc tattctacca
    13981 acttctagag tacccattgc tatcttaaat ccttgacctt cttttccaag taagttttct
    14041 tttggaactt taacgttttc aaatattaag tcagaagttt cagttcctct tatacccatc
    14101 ttatcttcat gagctcctgt tgagaaacca tcccatttac tttctactat aaacgctgat
    14161 gttcctctaa gtcctttact tctatctgta actgctatta ctatagctac atcacagaat
    14221 ggtccattag ttatgaaagt ttttctacca tttaatatat agtggtctcc aactaattct
    14281 gctgttgttt gttgtccacc tgcatcagaa ccagctcctg gctcagttaa accaaatgct
    14341 cctattaatt cacctgttgc tatacctttt aagtattttt gtttttgctc ttcagtacca
    14401 ttgtaaagta ttggtaatga agcaagagaa gaaccagctg taacaaaagt agctgttgaa
    14461 gcacatcttc tagctatttc ttccattact atagcgtaag aaacatatcc tgctccccca
    14521 ccaccatatt cttctgggat attactgctt ataaattttg catcagctaa ttttttgatt
    14581 aattccttag gcattacacc tgttttatcc atttctgctg gtaaagtatc taattcttta
    14641 ctaacaaaat ctcttactgc ttttcttaaa agttcttgtt ctttgttata taacatagct
    14701 tcctccaatt ttcatatttt atagtaaatt tattttaatg aacttacgct aaactcatca
    14761 tctcagcaaa agtttgaata cgagttctgg cttgttcatt attctgagtt tgttggtcga
    14821 tttcaacata taaagtaggt attccactat cttctatatc ttttctaact aaaggataat
    14881 cgtattcttc tgggtcacag aatttcatca tacagaagat aacaccatct atatctttct
    14941 ttttaacttc atctactata agtgacccac gttttttctt agggtcataa gctaatgaac
    15001 atccttctat gtttgaccat tgtcttgcta atctctctaa cgcatcatca cctgctggta
    15061 catctgttct gaattgtctt gtttcttgtg ctaagtcgtc agctacaact gatatattgt
    15121 tgtcttctaa aatgtctaat atatctttag aatcagctaa tatacctgtt aataaaactt
    15181 tctttccaga acagacttct tctggcatag catttaattt tgctattaaa tctttcacta
    15241 gctcagtatg ttcttctttt ctcataaaga acccactctt aattactaag cttcttattg
    15301 atggttttat agtattagaa tgtttataag ctacttcaac aaagtctctc atagtttttc
    15361 tatgttcatt gtaaacttct atactttcat gaatttttgc ttcttctatt tcatatccac
    15421 aaatttcttc aagttctctt tttacgcctt tgtactcact gattaagtat tttacaccag
    15481 cttcaagttt tctattttgt gggtgtacta atgatatata ttttatatga ggtactgctg
    15541 atttccagtt ttgtcctaaa caaattagtg tatcacacat acctggtata ataactccag
    15601 ataattcatc ataagcacct tttaatccat attctaaaca tgattgcatt attgaacatg
    15661 caaatgcagg gaaatattgt ttagctaaat ctaattctgt ttgtcctccc catataccaa
    15721 ctggaagcat tccagctgca tgtataattt cttctgggca ataaactggg aaacaaccta
    15781 tagctttttt accagtttca cttttatatt tttttacagc cgcatttgga ttttcaacta
    15841 cttctttcat tttagataaa atagcttcca ttatatctca cctctattaa gtttttttct
    15901 ttcttccatt acttcaacta aaccttgaat tcttgtttca aattgagcat tagtgaaagc
    15961 tctagggtct gcttggtcac catcaaatcc agcatatggt aatccagttt cttcagctgc
    16021 tcttctttgc atttcatatt gtattaaact cataagttta cagcttctgt tcatatgata
    16081 gaatgctcca tcacatttac cctctactaa agaatcaact ctatattttg tcatacggtc
    16141 taggtttaca ttgttaaaca tagtactata tgctactgcc attccatcta aatcattaac
    16201 ttcatattgt aatgcccaag catgtgggta aacactacct gtcatgttaa ctccaaattt
    16261 agctaatgtt ttcatcttgt atcctatata tggccaacaa ggtatacctt ccatcattat
    16321 tctgtatttt tcttcccctc tgaaagaaga tttaccagtt ttcatgttgt cctctaattc
    16381 ttctataagt aacttaaatg cttctgtagt ttctttttta cctctagcac aaactattac
    16441 agccatgtaa gtaaataagt caaatccatt cattggagaa ggagaagaat ctgctggtaa
    16501 actcatagaa tacttccata gtcttccgtt ttcagctgat attttcatta cttcttcaaa
    16561 cttcttaggg tcaaatttct ttcctgatat aatttctagt tgttttatag cttcttcaaa
    16621 ttgagcttta atataatcta ttcttgattg agtaacttcg tcttcattat tgaaagttgt
    16681 atcaatcatt attaaaggta tatctaattc tcttgaaata ttttcatacc attttataac
    16741 ttggttacat atattgttac agcaaagtag gaaatctgga gctggcatat ccaaagcttc
    16801 acatccacca ttttctaaaa gaccaaaatt tgttcttgca tatgcacata ggtcaataga
    16861 atatccttta gattcagcta tttcacataa ttctaaagaa ccttttttag ctgctactcc
    16921 agctgcttgg ttttctggat ataatacgtt taagtcaaat acttctgcta actcttgagg
    16981 aaatactgat gttgaccaac ctacaggtct tccttcttct ttagctttaa atgcatttgc
    17041 atattgttca gctaataaat cattaattac tactctagct tctttttttt cagacatttt
    17101 catccctctt tttatatatt tttcacttct ttttgtgatt cttttgcttc atcaaaagca
    17161 tataacgctg ctcctaaagc accagttaat tgaggtatat caggtacaat aatttctgtg
    17221 ttgatttctc ttgccatagc tcttacaata ccactatttc tagcaactcc accaaccata
    17281 actacatttc tttgtactcc tattcttttt actaggctag aaactctctt tgctactgaa
    17341 gtatgaatac ctgccactat atcttcaatt tttgcatttt cagataaatg tgatataacc
    17401 tcagactctg caaatactgt acatgtactg cttattgata cttcattttg agaattcata
    17461 gatatacttc cgagttcaga tacatcaacc tctattattt ttgccattac atctaaaaat
    17521 cttcctgtac ctgcagcaca tttgtcattc ataagaaagt ttaatagtct tccattatta
    17581 tctaatttta atacctttgc atcttgacca cctatgtcaa taatggttct tgtctctgga
    17641 attatgaaat ttacccctct agcatgacag cttaattcac ttatttgctt atcagcatct
    17701 gaatagttca ttcttccata tcctgtaact acaacttttt taatatcttc tcttgcaaga
    17761 cctgtcttgc catataattt ttctaaaact cttgatggtc cagtagtccc agtaccagag
    17821 gatattgttt cagaagctac aatatcttcc ccattcttta agattactcc ctttgatgca
    17881 gttgaaccta tatctaatcc cattgtgtac atctttagca ttctcctttt aaaaaatcta
    17941 gaattactaa ttaatatctt acaactttac tatctttaaa gttatttatt ttctcttcat
    18001 cgtagcctaa agattttaat acttctacag tatgttgacc tacttttggt gctggtgtat
    18061 attctttaat tccttcattt ctaaacataa ctggagtatt aactaagaca cctgtatttc
    18121 cgctatcgta tgttttctta aataagaagt catttgccca agcttgttcg tcatctaata
    18181 aatcttcaca gctttgaatt ttttcaaatg gtaagtctgc ttcttctaat aaagctgacc
    18241 actcgtctaa tgttttttct aacatagctt ctccaactat cttaactaaa tcttcaacat
    18301 gattaaccat tgaatctatg ttattatatc tatcgtcttc taatatatat tctctattta
    18361 taaccttaca gaatttgcct aaccacttgt tgtattgtat taaagctaat tgaatccatc
    18421 ttccatcttt acatttatat gtagtcatta atgggctgtt tggattttct cttgataaag
    18481 gcatttcatt tccgtattgt gctgttgtta tcattgttcc cattccatat atagctgtat
    18541 ggaaaagact tactgttact ctctcacctt taccagtttg agctttttta tgtaatgctg
    18601 ctaaacttcc tgctgctagt gctagacctg catagtggtc accaaatcct gctgctgtat
    18661 ttgctggaga tgttcctttt tccataacag attggctaac tcctcctctt gcgaagtatg
    18721 cagtatagtc aaatcctggt ttatctttta aaggtccttt ttcaccatat cctaatattt
    18781 gagagaatat taatcctgga tacttatctt ttatttggtc ataagctata cccatttttt
    18841 ctaatgcttg aactctaaca ttagttacaa atatgtctgc ttctgataat aatttatgta
    18901 atatttctac tccttctttt gattttacat taatacttac acccttttta tttccatttt
    18961 ctaattcaaa catagggttt tcatcatctg atgctggaga tttaaatgtt ccacccataa
    19021 ctcttattcc atcaccttct ataggttcaa tcttaataac ctctgcaccc cagtcaccta
    19081 acatttttgc acaacatggt gctgcgatga aacttgaaag ttctactact ttaactcctt
    19141 ctaaaagcat aacgttttcc tccttaatag tatcaattat aaaatttcga ttaaatcact
    19201 cataaaatac ttttttctga tattaactgt ctgatgtcaa agttcctaat cttatctaaa
    19261 ataacttaaa aattattaaa attatttttt attgttttat tgtcttacac ctatattgtt
    19321 aagcatttat cgtgccaact ttatatttaa tcaaaatatc gcttgatttg aatgtttttt
    19381 aacaatatgc aattgaataa tctttttcat atcgtggcat cttgccacta tccattgcat
    19441 tttgctattc tttctctgct tataaaagtt ttttttatat atttttttat gaaaaagctt
    19501 gacatttcaa aaaaagtttt cattgctaaa ctcaaaaaca catgttatca ttgtaattaa
    19561 tcagcaagtt agttaactaa tttcaaactt agataatttt ttaataatat ttaatctaaa
    19621 aaataacaat ttctttgata aattttagag taattattac attaaataaa aaattactaa
    19681 atatcaaaat aacacaggga aaacaatttc aaaactaaat ttttaacctt aaaaattttg
    19741 tataaaaaat ataaccttat atgctacata ttatttctaa atgaaaaatt accataataa
    19801 tttaataatt acaggagggt attgatatga aaatactagt atttggagca cgcgattatg
    19861 aagaaccagt aataaaaaaa tggtctgaag aacataagga tgttcaagtg gatatttatc
    19921 ctgaaaacat gactgaagaa aatgtagtta aagctaaagg gtatgatggt atatctatac
    19981 aacaaactaa ctatatagat aatccttata tttatgaaac tttaaaagat gctggggtta
    20041 aagttatagc ttcaagaact gcaggggttg acatgataca ttttgattta gttaatgaaa
    20101 atggacttat cgttacaaac gttccttctt attcacctaa tgcaatagct gaattagctg
    20161 ttactcaagc tatgaacctt ttaagaaaga ctcctctagt aaagaaaaaa gtctgtgaag
    20221 gtgattaccg ttggatagct gaacttcttg gaacagaagt tagatctatt acagttggtg
    20281 ttataggtac aggaaaaata ggtgctactt ctgcaaaatt attcaaaggc ctaggagcta
    20341 atgtaattgc atttgaccaa tatccaaata gtgatttaaa tgatatatta acttacaaag
    20401 attctttaga agaccttcta aaagaagctg accttataac attacatact cctttacttg
    20461 aaggaacaaa acatatgata aataaagata ctctagctat aatgaaggat ggagcttaca
    20521 tagtaaatac tggccgtggt ggtttaatta atacagggga tttaatagaa gcactagagt
    20581 caggaaaaat tagagctgct gcccttgata catttgaaac tgaaggattg ttcttaaaca
    20641 aaaaaatgaa tcctggagaa ttaactgacc cagaaataaa taaacttctt tctatggaac
    20701 aagttatatt cactcatcac cttggtttct tcactagtac agcgattgaa aatatagttt
    20761 attctagttt aagcagtgct gtagaagtta taaaaacagg aactgctact aatagagtaa
    20821 attagtattt tataaatata ttttttcatt aattagctat tatctaacaa aatagccttt
    20881 aatttcccaa atataagaga gtcagctcag tatatattga gtagactctc ttatattatt
    20941 ttttatatta aacttgtact cttcttattc ataccaaatt aaatttatat taacttattc
    21001 taactactcc tactctatac attttaccta tttttacttt tctaattata tacatttgaa
    21061 tgggtacaat ctgtatttta caaaaaaaac acctaacaaa ctatgaaaat tgtatgatta
    21121 atattaatat atttataaga aaacataaca attatgttag ctctggattt ttagggaggg
    21181 agtatattgg aaaaaatgaa taaagttact tctaaaaaaa ctacctatat tgttacttca
    21241 gcattatttg catccataat atgcctgaca atagcatata tattacatat tccagttggt
    21301 ggaaacaatg gatatgttca tataggagat gcttttattt atctagctgc aactattttg
    21361 ccaacaaact atgctatagc tgcttctgca attggtgctg gtctagctga tttatctaca
    21421 ggtgctgcta tctgggtaat accaactata atcataaaac caatacttgt attatttttc
    21481 acttctaaaa gtgacaagat aataaataag agaaatatag ttgcttcggt tgtagcaggt
    21541 atagtaggat tagttttata catgtttgct gaaggtataa ttattggaag ttttacaagt
    21601 gcatttgtaa tgagcttact tggcttatta cagccaatag gaagttttat tgtttttata
    21661 atcttaggta tggcacttga taaacttgat tttaaaaaac gttattttaa ttaagaattt
    21721 aaatttatgg agggaaaatt atgaatatct tatatacaat tgaaaatagt atctatgtaa
    21781 atataactaa tacatgtcca tgtagttgtg ttttttgtat aagaaacgaa aaagatgaag
    21841 ttgcaaatag tggtagttta tggctggaac atgagccaag tgtagatgaa gtaaaagaag
    21901 ccttcaataa atacaattta gacgactatg atgaaatcgt attttgtgga tatggcgaac
    21961 cattaatgag aataaatgaa ttgatagagg tagcaaagtt tataaaagaa aaaagtagca
    22021 taaagataag aataaataca aatggtctaa gtgatttaat acataacaaa aaaacagcta
    22081 ttctgttaaa aaatgttata gatgcagtat caataagtct taatgcccca aataaagaag
    22141 cttataatag agttactcaa ccaaagtttg gagaaaaatc atttgattat atgttagatt
    22201 ttgcaaaaga ttgcaaaaaa tatataaaag aagtagcttt ttcagtagta gatgaaatat
    22261 ctccagaaga aatagaagaa tctaaacaac tggcaaaaaa acttgatata ccattaaggg
    22321 ttagacataa gaattagcaa gtaaaattat aaaacattaa ttataaaaca ttaagaatca
    22381 cctgaatggt ctttcaggtg attcttcctc ttgtattaac attttacaaa atagatttca
    22441 taccacacta ggaatgtgta aatcatccaa atctttctcc aattatcaga gtttccacta
    22501 atgtagtcat taaaaatctc attaatctca tctatgttaa agaatttatc tgctatctca
    22561 ctattgaatt tatctcggat gtccttatta tattggtcat cagccatcca tatacgaatt
    22621 ggcacaataa atcctaattt atttctaaaa gcaatctctt ctggtaatgt ttttgatgca
    22681 gctgtacgaa aggcaatctt attctctttt cctttcactt tatattctga tggtattctg
    22741 gatgcaatat caaatattct tgtatctgta agaggcattc tgacttccaa tccaactgca
    22801 gtactcattt tatctatatt aaaataaata tctccttcca accatatttg aatatctaca
    22861 tttgacatgt tagtaagtgt atctagttct tctgtttctt cataaattcc ctttaccact
    22921 tcaataggaa gcacatcagg attgtatttc ttaagaattt ttcttttctc accctcattc
    22981 ataatgtttg tatttccaat ataaaatgtc ttcaaattct ctccataaca ctctgcctta
    23041 tggtatatat tatatccacc aaaaaactca tctgctcctt ctccagagta acagatattt
    23101 gtgttttcag ctgctgcctt gcatccaata gcaaaaacga tagcagatgc atctccagtt
    23161 ggttgctcca tatggtacat tacataaggt actgacgcaa aatactcttc aggtgtaatt
    23221 atatatctcg aatttttaca cccaagaata ttagctgtct gttgtgctaa ttttgattca
    23281 tcaaaacgct cttcctcata accacatgaa cctgtttttt ctatatctga cattgccaat
    23341 atataagatg aatcaacacc tcctgatagg aataactctg cagtttcatt ctctgatttt
    23401 acctctggca taattttctg aagtgttgta tgaatttcat ccgtccattc ctcaatagac
    23461 ttgctgtggt caggatgaaa ttcaggtttc caataacgac caatacatac tgttttattc
    23521 tgatagacaa ggtaatgtcc tggcataagc ttctttactc cacggaagaa tgtattttca
    23581 cctgctacat atgtgaaaga catataaatc tgtaacatgt cttcatttaa ctctttcaca
    23641 aatcctggtt gctccataat cttacgaata gatgaaccat agagaagctt cccattttca
    23701 gtctcataat aatagaaagg ttttactcca aactggtctc ttaggcagaa gagtttcttt
    23761 tccacagtat cccataatgc aaaagcaaac attccatgca tgtgatttgc catatcatat
    23821 ccccatgtct tatatgcttc cactaaaatt gctcgttcac gctcatctct acataatgaa
    23881 gaatcgattc caagttcttc acagagaact ttccagtttc gaatatgtcc attgtattct
    23941 agaattttta tcatatatgt gtcttttcgt gttaaatact tttcttctaa atttatcata
    24001 tgtgtatcct ttcgtattaa aacatttaac ttctaaattt attaaatgtt tatatatatt
    24061 tattcactta taatcactga aaaatcgact tttttcaaag taaattcttt ttgaattagt
    24121 actaatctgc tctttattaa tggcatcaat atgattatca agtattatca gtgttataac
    24181 actgaatttt ttattcttca taaatattgc tccctttata ttaccaacta aatataatat
    24241 atcttatgtt acttacatat tctttaagaa attctgaaga ttttataaag ttttttgtat
    24301 tataatcaat taaaaataaa attctagtta taaagcatat tttccattaa acaaaaaaat
    24361 agttaaa
//
LOCUS       DAMJXI010000054        24180 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.056, whole genome shotgun sequence.
ACCESSION   DAMJXI010000054 DAMJXI010000000
VERSION     DAMJXI010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24180
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.056"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            74..808
                     /locus_tag="PC465_002722"
     CDS             74..808
                     /locus_tag="PC465_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2650008.1"
                     /translation="MKQNKYDDDRFFNKYSKMERSTNGLAGAGEWHVLKKMLPDFKGK
                     RVLDLGCGFGWHCQYAVENGAISAVGVDISEKMLKEARNKTQLDNINYICMPIEDINF
                     PKDSFDVVISSLAFHYIQSFEDICKNISNCLSNKGNFVFSVEHPIFTAYGSQEWYCDK
                     DGTNLHWPVDRYFEEGVRKSNFLGEEVIKYHKTLTTYLNTLMKTGFEILEIIEPQPEE
                     KLLDTIPDMKDELRRPMMLLVSAKKR"
     gene            complement(951..1442)
                     /locus_tag="PC465_002723"
     CDS             complement(951..1442)
                     /locus_tag="PC465_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HDF2650009.1"
                     /translation="MNNQQQEVYKKLDELSIPYEAVNHPPVYTIEEMEELKTLHMEFV
                     VKNLFLRDAKGKEHFLVVLGKDKKADLKDIRQQIDSKPLSFASEERLQKYLKLTKGAV
                     TPFGILNDKEAVVKVVFDKDLLKMDKIGIHPNDNTATVFLKFEDMKKLIEENGNEIYY
                     VEV"
     gene            1791..2174
                     /locus_tag="PC465_002724"
     CDS             1791..2174
                     /locus_tag="PC465_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650010.1"
                     /translation="MSTDKVVGIIDEETAELAGIEYTGKIYASSGVIKHIKKKHRCQL
                     SKDIFNDIIDTIKMVLKSPEYIGSHPKKPGKSVEFIKKIDDYILVATELDTKKEYLYV
                     SSMYAIKEAKLESRVNSGRVKQYNG"
     gene            2680..3063
                     /locus_tag="PC465_002725"
     CDS             2680..3063
                     /locus_tag="PC465_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDF2650011.1"
                     /translation="MNLSKKIEDKRKAKQRAEKVKKAKIATAGVVLGAVTGAVSGVLL
                     APKSGKETREDIKDASQQIAEKINMKTVDVKGKVSEKLEDKKGNFIESKKKIKKYIDN
                     KKSVENSSEEDKIIDIVEPVSVTEE"
     gene            3065..3415
                     /locus_tag="PC465_002726"
     CDS             3065..3415
                     /locus_tag="PC465_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650012.1"
                     /translation="MDNTITINISIIYVLLAILACIALVYLIIVLVKLHKILNNVGTM
                     LNENTQNINTTLNNLPNVVETFGEVGENMKDVTEVVTEVTADFLVTKDSVKSNMDVIV
                     DILTIIKNIFLDKK"
     gene            complement(3516..3974)
                     /locus_tag="PC465_002727"
     CDS             complement(3516..3974)
                     /locus_tag="PC465_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650013.1"
                     /translation="MIRTKVVELIATVCRENKPHKWVDENYTPYDKSGKVELMSIEDL
                     NELISSSGRADFLYSSRLQKLLNEVYINQSRASYISGCGLFWSSYWDILEERFEEWLY
                     NSYIFFDEDDEYLEGMEDFELECKDVLMDVIETTSIDIYVQMIKRNITNY"
     gene            complement(4019..4807)
                     /locus_tag="PC465_002728"
     CDS             complement(4019..4807)
                     /locus_tag="PC465_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2650014.1"
                     /translation="MKVVIIPGHTLIGKGTGAVGYINESKETRILNDLIVKWLKIGGA
                     TVYTGRVDESSNHLADQCAIANKQETDLAVQIHFNSNATTSTTVGTETIYKTNNGKTY
                     AERVNTRLATVFKDRGAKSDVRGLYWLNHTIAPAILIEVCFVDSKADTDYYVNNKDKV
                     AKLIAEGILNKSISNSQGGGENKVYENVIVYTGDADKVAAQILHWQLKDSLIIEASSY
                     KQGLGKKVYVVGGEANKLVKGDVVINGADRYETVKLALQEIDKL"
     gene            complement(4946..5383)
                     /locus_tag="PC465_002729"
     CDS             complement(4946..5383)
                     /locus_tag="PC465_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HDF2650015.1"
                     /translation="MNKKLENRCSWQEYFMRLCETVAERGTCDRAYVGAIIVNSENRI
                     VSTGYNGSISGDKHCSEVGHEMRDGHCIRTIHAEQNALYYCAKEGISVKNCSIYVTHF
                     PCLNCTKAIIQAGIKHIYYRTGYRIDEYAIKLLQSSNVLYTKL"
     gene            6205..6714
                     /locus_tag="PC465_002730"
     CDS             6205..6714
                     /locus_tag="PC465_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2650016.1"
                     /translation="MLSENIKTIRKSKGLSQQELAIKLNVVRQTISKWEQGLSVPDSD
                     MLISISEVLETPVSTLLGETIVESEVDNLKVISEKLEIINLQLAQRKNMRRKMFHWLF
                     ILLCAVILIVFVVLGRLNSPYLDWNYTDPETAVFGVAFHAFEWLFVRLVPIVLIGAII
                     GIFLTRKKI"
     gene            complement(7612..8412)
                     /locus_tag="PC465_002731"
     CDS             complement(7612..8412)
                     /locus_tag="PC465_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2650017.1"
                     /translation="MRLNKRSEGYINYVKGVKREKRNVLFYQLLILIGFIVIWELLAD
                     LNVINTFLFSKPSDIYNLFIQYAFSGQLFKHIGISVYETVLGLVIGTVLGILVAIALW
                     WSEKLSKILDPFLVVLNALPKTALAPIIIVWVGAGIEGIVVTAVTISVVVTILSAYNY
                     FMNIDEEKIKMLKSFGATKSQILFKLILPANTGNLINLTKINIGMAWVGVIVGEFLVS
                     RYGIGYLIVYGSQVFKLDLVMMGVFVLAICAWAMYAVVNIIEKIYNSR"
     gene            complement(8402..9154)
                     /locus_tag="PC465_002732"
     CDS             complement(8402..9154)
                     /locus_tag="PC465_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011098710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2650018.1"
                     /translation="MNDNIVEVKNINMNFYTKEGELEVLKDVNFNLKEGEILTLLGPS
                     GSGKSTILNILTNLLKPTSGDIKITGNIGYMFQKDNLLEWRNIMDNITIGLEIQGKKD
                     KKSLDRVESLLKTYGLWDFRSMYPKELSGGMRQRVALIRTLSVNPDILLLDEPFSALD
                     YQTRLLVCDDVYSIIKNENKSTILVTHDIGEAISISDKVAILSKRPATIKNIYDIELN
                     MDGTKTPLKTRKVPDFQKYFDILWKELDTHEA"
     gene            9324..10682
                     /locus_tag="PC465_002733"
     CDS             9324..10682
                     /locus_tag="PC465_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650019.1"
                     /translation="MSNIITNLIESIFTNPITILFLLAITVYSVFKIIENNRVYSFVS
                     SKLDEINRDYKTSEFYKKVRDDYYTYSKENPYADVNITSFIEEVVSDLKHNNLPLLEK
                     IRSIKNSSSISILLGVLGTFVGLSTMLLCVDTKDIINSLPSTISSMQTAFTTSIFGVV
                     FSLIIGYFTKIKDCEHVLIQIMLKSENLLTSEITHFKSERMDLKVEEVKNTIKQISKS
                     IEAIEKFDKISKDLNDFNDEFISGIEALKSLLEGSQSSIKTFDQSVRKLDKQFNILNI
                     KFVKLFDKYDNQDNINKEILFDIKESSKNIYNATESQFKIRDYIKNINAGFALYERSA
                     QDLLTKLMTHENKISQNQKILLDEKFTLDDSIKNLSSIIENFSNDLQVKLDMMFENSL
                     DIQDKLDVMFNNSFMNDEVPLDSEKLFKDDVNNVFNPFSEEIYEIEDKEIKVIGEDEL
                     NE"
     gene            10675..11307
                     /locus_tag="PC465_002734"
     CDS             10675..11307
                     /locus_tag="PC465_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDF2650020.1"
                     /translation="MNNKYIRTVNREFEKSSFWPTFTDLLSTVLMVVILILFSSESIS
                     GSVEQDLAKNVNASVEETFKKSGIPVKVDKSNGQVTFGEKTMFDIDSDVLKPEAKEML
                     KMFVPKYIETIYKDYGDYISKIVIEGHTDDVGSYIYNLDLSQRRAYSVAKFIVGDEIG
                     DYKYKDKVTKHIIAIGRSKAELIKNGDNSVNRDASRRVELKYEININQNK"
     gene            11636..12793
                     /locus_tag="PC465_002735"
     CDS             11636..12793
                     /locus_tag="PC465_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2650021.1"
                     /translation="MIEISIKNKKNSKIKTLILLLIVSISIYLTGCTTSDNGNNQSNN
                     NDSLSSSISSDKNVKIHFIDTGNSDAILIQDGKTFTLIDGGDNDDEGLMVDYLNNQGV
                     KDIKYLIATHSHADHLGGLDSVVKNFNIENVFVSNGSAETKSYRDFINALANKGLSPS
                     VPLENNKFYLEDSYFEVLNTNGGDTTNEQSLVLVYTNGNDKVLFTGDAEEGTEKEILP
                     KLEKVDLLKVAHHGSRSSSSQEFLDKVNPEYAVLLVGKGNSYGHPHQETMNKLKKMGV
                     KVHRSDECSDIIFESTGDGVFTSCKDGSYNKGVREDGNSGKSNSNTSKNDSFKNKQNT
                     SNSEEIVYFTPKGKSYHSTKNCSGLSRSKKILSGTIAESKKNDPCDICYGK"
     gene            complement(12940..13575)
                     /gene="lexA"
                     /locus_tag="PC465_002736"
     CDS             complement(12940..13575)
                     /gene="lexA"
                     /locus_tag="PC465_002736"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HDF2650022.1"
                     /translation="MYLDLTEKQVLILEFIKSQIILKGYPPAVREICTAVGLRSTSTV
                     HSHLNKLEKLGYIRKDPTKPRAIEVLERSKVNDVSGANQEIIELPLVGQITAGEPILA
                     QQNIEEYIPFPASLVKGSNNFVLRVKGESMINAGILDEDYVVVDKKNTALNSQIVVAL
                     INGESATVKRFFKEGNLIRLQPENDFMEPIMLNDSEVEIVGIVTGVFRVIK"
     gene            complement(13679..14806)
                     /locus_tag="PC465_002737"
     CDS             complement(13679..14806)
                     /locus_tag="PC465_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2650023.1"
                     /translation="MNNDKKIIKVHNKSDKPDNIVIKENELIEKCLLLENKLPVFMKD
                     YFIYLKGSVAVSTRLAYLEDINFFCSYLIETKELTNADCVKDITEDDFNTIKSRDINL
                     FLGDYCSRYYKNTEKNTLIFENNNRALARKKSSISTLFKFLYRNSQIDNNITDGFNPI
                     KLPKPQPDAIKRLEIDEVAKMLESVETGEGLTEKEKVYWRKTKLRDKAILALFVTYGL
                     RLNELRELNISSFNFSRGEFKIYRKRGKEVLMPINHTCEHVIKDYLQNERTRDELLND
                     EEKDALFLSLQNKRITAKAIRTLVKKYTSIPLDTTRDNGYSPHKLRATAATSLIQTGF
                     SIYDVQNLLDHDNVTTTQLYAAHKKNVKRDIVKNFEWIEDD"
     gene            complement(15127..15972)
                     /locus_tag="PC465_002738"
     CDS             complement(15127..15972)
                     /locus_tag="PC465_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650024.1"
                     /translation="MIYIIEILKISVINIFCFIGIFIVFGLIFSITENLNNKFIFSSF
                     GKTGIIVTGAIGTFVHELSHLIMCLIFMHKINSVKFFRPIESKNDGILGYVSHSYKKD
                     NLYQSIGNFFIGIAPIIGGTIMIILIFKILLPDSYMKVTQNINLKLYVSMINNLNING
                     FIHIILGDISNFIRIMLLTPSVYSLKYFIFMFLMYSISTHMSLSSADLKNSLNGLSFI
                     VIVIFVISSITYLFGFDNLNISSLIVKYNIFISFFMAIGFIFSIVTLIISYILSLVSP
                     FKNFS"
     gene            complement(16002..16373)
                     /locus_tag="PC465_002739"
     CDS             complement(16002..16373)
                     /locus_tag="PC465_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDF2650025.1"
                     /translation="MKLKLLVEEYAVCRLNNDSKIPTWIDTEKFYSITRTDDELSVVC
                     LNNNIPSDVKSEKEWRILKILGPLDFSLVGILSKLSSLLADNKISIFAISTYDTDYIL
                     VKEKDIENACKILSCNGYEVE"
     gene            complement(16526..16786)
                     /locus_tag="PC465_002740"
     CDS             complement(16526..16786)
                     /locus_tag="PC465_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003866776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein S"
                     /protein_id="HDF2650026.1"
                     /translation="MEVLKVSSKSNPNSVAGALAGVLRERGVAEIQAIGAGALNQAIK
                     SIAIARGFVAPSGMDLVCIPAFTDIEIEGDKKTAIKLIIEPR"
     gene            complement(16975..17919)
                     /locus_tag="PC465_002741"
     CDS             complement(16975..17919)
                     /locus_tag="PC465_002741"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HDF2650027.1"
                     /translation="MIENNSEKIKVLENDIKQLITISKANNIDLSDKINSLNEKLEKL
                     KEDAFSHLSAYEKVTLSRDIKRPTTLEYIEHICSNFLELHGDRLFKDDPSMVGGIGQI
                     GKFNVTIVGHQKGRDTKENIKRNFGMPHPEGYRKALRLMKQAEKFNRPIITFIDTSGA
                     FCGLEAEERGQGEAIARNLLEMSKLSVPVITFVIGEGGSGGALGIGVGNDVCMLEHSV
                     YSVISPEGLSSILFKDSSKAKEACDVMKLTSNDLYDLKIIDKIIKEPLGGAQKDVEAV
                     SKEIKAYILERLNHYKDMDKEEIIAQRYKKFRNIGKCL"
     gene            complement(17940..18794)
                     /locus_tag="PC465_002742"
     CDS             complement(17940..18794)
                     /locus_tag="PC465_002742"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HDF2650028.1"
                     /translation="MIKKFLSSKESKYVTISLDDNFKKNSVDDKFWTYCKGCDSHVFR
                     KDIEENSFVCPKCSRHYGLRARKRINLLIDKGTFMEFNSDVEFQNPLNFPKYKEKVDS
                     YKEKTKESEAVVTGYGRINGIKTVICVMNPDFMMGSMGSIVGEKITYSIEYAAENNLP
                     IIICSASGGARMQEGMVSLMQMAKTSQALSKLEEKSLPYISVLTDPTTGGVTASFAML
                     GDIIISEPNTLIGFAGPRVIEQTINQKLPEGFQTSEFLLEKGFIDMIVDRRKMKEVLY
                     QILAMHKK"
     gene            complement(18809..20170)
                     /gene="accC"
                     /locus_tag="PC465_002743"
     CDS             complement(18809..20170)
                     /gene="accC"
                     /locus_tag="PC465_002743"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HDF2650029.1"
                     /translation="MIKKILVANRGDIAVRIIRTCKELGIKTVAIYSEIDKDCFHRYI
                     ADESICIGPNNISKSYNNIENIIYLALKLKCDAIHPGFGFLSENPEFAKQCEDNNIIF
                     IGPTREQMILMGDKSRARETMMELNIPVVPGSESVLKTKEEALEVAREIGYPVMIKAS
                     SGGGGKGMRIVRKEEELFSNFDMASSEALAAFSNSDLYMEKFIENPRHIEVQVFGDKH
                     SNAIHLGDRDCSMQRRNQKVIEESLSPYLSDEERQKLHKIAVDIVKGVGYIGAGTIEF
                     IVDKDKNFYFIEMNTRIQVEHPVTEMVTNLDLIKLQISIANGDKIPFKQEDITFRGHA
                     IECRINAEDSSKNFAPSPGKIESLNLPGGFGVRFDTFVYAGYTIPPLYDSMIGKLICW
                     AETREECISRIYRALDEIIVEGINTNVEFQKALVTSEEFREDTHHTKFIEDVFMKKEF
                     ATL"
     gene            complement(20186..20638)
                     /gene="accB"
                     /locus_tag="PC465_002744"
     CDS             complement(20186..20638)
                     /gene="accB"
                     /locus_tag="PC465_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HDF2650030.1"
                     /translation="MNINEIKELLKAIDSTNLEYVKLESSDLRLEVSKKAQSTSSPVL
                     SVQQESVVDLSLEKPVVNDTPVTSNENLSVVVAPLMGTFYDSPSPDADSFVKVGDVVE
                     EGDTLCILEAMKLMNEITSEIKGEIIEVLVSNEELVEYNQPLFKIKPL"
     gene            complement(20908..21354)
                     /locus_tag="PC465_002745"
     CDS             complement(20908..21354)
                     /locus_tag="PC465_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650031.1"
                     /translation="MESKFFNWYTQSLGGTFGIISCICAYLNGYMFVYTNSASKYFES
                     IGFLGIISSYTLLPLCMLTLIFGVIYSYTPETSDKSIFNIPFFTLNKRLILITVVFGF
                     IGARVYFIIPAILITFNLYSNVLIAKLKYILCKNKENDTNLKESEV"
     gene            21629..21907
                     /locus_tag="PC465_002746"
     CDS             21629..21907
                     /locus_tag="PC465_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650032.1"
                     /translation="MVDTLEFGLKILFFILSIIWMGKIMILRTDKQIVINPLLIGISA
                     VLVMLHTSQSNIEFFGLDVQYIRIVLYIIYSLIILIGIWATNRRNGIF"
     gene            complement(22036..22782)
                     /locus_tag="PC465_002747"
     CDS             complement(22036..22782)
                     /locus_tag="PC465_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650033.1"
                     /translation="MWEGTMNLANLIPFIISAAALSPINSNDKVLSENQLKDIFPDAN
                     LRAVVKRYINPDEMTISNIKALDGEFYATGESISNLKGISYLENVDNFIFWNNNIKEV
                     PKEALSLKDMDSINLANNYLIDDDVVNSLSHNGVDVNCDLNFIDTKDNQYKLDSKYHN
                     VDIAKGESIDLRKIITKKIDSYYKYWEVTDNLPKDLNFIVSVSDKSVLSCEDMIIKGN
                     KTGQAVVKVILSDKNDLNTSQEVLITVNVK"
     gene            complement(22911..23555)
                     /gene="trmB"
                     /locus_tag="PC465_002748"
     CDS             complement(22911..23555)
                     /gene="trmB"
                     /locus_tag="PC465_002748"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HDF2650034.1"
                     /translation="MRRRRKKGADEKLLSYTKYVLRDDIDKLKGKWNLKFRNDNPIHV
                     EFGTGKGKFITTLAKQNPDINYIAMELKEEVLLKAVEKADASNLNNILFLWGDVSNIL
                     DYFEAKELSRIYINFCDPWPKNRWSKRRLTHSGFLEMYNRVLEDDGEIHFKTDNEKLF
                     EFSLNEIAANNWLLKNISLDLGNSEYENNVTTEYEDKFMSQGMRIFRCEAKKRN"
     gene            complement(23693..24013)
                     /locus_tag="PC465_002749"
     CDS             complement(23693..24013)
                     /locus_tag="PC465_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein HesB"
                     /protein_id="HDF2650035.1"
                     /translation="MKITLPETAIDTLKSILKDNQDKPNNIRVYFAGVGCGGPSFGLA
                     LDEKKEDDLTYEVGELQFVMSSDEYSQYGDIIIEDTGFGFRVIPENMKDQGGGGCSGC
                     SGCH"
BASE COUNT         8645 a         3575 c         3015 g         8945 t
ORIGIN      
        1 aagtgataaa aacttatatt ttgtgtttag tagagtgttg ctaagtgaat atatttaaaa
       61 tggaggaaac tttatgaaac aaaataaata tgatgatgat agatttttta ataaatacag
      121 taaaatggaa cgttctacaa atggattagc aggtgctgga gagtggcatg ttttaaaaaa
      181 aatgttacct gatttcaaag gaaaaagagt tttagattta ggatgtggat ttggatggca
      241 ttgtcaatat gcagttgaga atggagcaat ttctgctgtt ggagttgata tttcagaaaa
      301 aatgttaaaa gaagctagaa acaaaacgca acttgataat ataaattaca tatgtatgcc
      361 tattgaagat attaattttc caaaagatag ttttgatgta gttattagtt ccttggcatt
      421 tcattatatt caatcatttg aagatatatg taagaatata agtaattgtc tttcaaataa
      481 aggtaatttt gtattttctg ttgaacatcc tatatttact gcatatggaa gtcaagagtg
      541 gtactgtgat aaagatggca ctaatctaca ctggccagta gatagatatt ttgaagaagg
      601 agtacgtaag tcaaattttc taggagaaga ggttataaaa tatcataaaa cattaacaac
      661 ttatttaaat acgttaatga aaacaggatt tgaaatatta gaaattattg aacctcaacc
      721 agaagaaaaa ctgttagata caattcctga tatgaaagat gagctacgta gacctatgat
      781 gttacttgta tctgcaaaaa aaagataagt aaatataaat aatcattatt gtagaaaaaa
      841 agttgtagaa aataattata ctaatggaga tgattatacc agtggtatta attacaccag
      901 tagtaaggag gcaaaagcat tcgttgcttt tgccattttt taagttgcaa ttatacttct
      961 acgtagtata tttcgtttcc attttcttct ataagctttt tcatatcttc aaattttaaa
     1021 aatacagtag cagtattatc atttggatgt atacctattt tatccatttt taataaatcc
     1081 ttatcaaata caacttttac aacagcctct ttatcattta atataccaaa aggagtcaca
     1141 gctcctttag taagtttcaa gtatttttga agtctttctt ctgatgcaaa actaagaggt
     1201 ttactatcaa tttgttgacg aatatctttt aaatctgctt ttttgtcttt acctaataca
     1261 actaaaaaat gttcttttcc tttagcatca cgaagaaata ggttttttac aacaaattcc
     1321 atatgtaatg tttttaattc ttccatttct tcaattgtat aaactggtgg atgatttaca
     1381 gcctcataag gtatgcttaa ctcatctaat tttttatata cttcctgttg ttgattgttc
     1441 atgatttcct cccattagaa atttatttta tatataaata atattatcac agaaaacttt
     1501 aaaagaaaac gttttatata atatagacaa tagattatat ttttataaag aagcaagaat
     1561 actcaataaa acttaaagaa attaaacaat ttctaaaaat accttgaaaa tagaacctta
     1621 tttgccattt ataaattata taaaaaggga ttatataaag tcatatatga aaaaactata
     1681 ttatactatc ttttcttttt ggaataaact atactttaaa tatagatatt taatttaaat
     1741 aaattttaca gtattaatag taaattatct tagaaaggaa tgtgctttat atgtctacag
     1801 acaaagttgt tggaatcata gatgaagaaa cggcagaact tgcaggaatt gaatatactg
     1861 gtaaaattta tgcttcttct ggtgttataa aacatataaa gaaaaaacat agatgtcaac
     1921 tgagtaaaga tatttttaat gatataatag acactataaa aatggtatta aagtcacctg
     1981 aatatatagg aagtcatcct aaaaaacctg gaaaaagtgt ggagtttata aaaaaaattg
     2041 atgattatat tttagtagct acagaattag atacaaaaaa agaatattta tatgtatctt
     2101 caatgtatgc tataaaagaa gcaaaattag aaagtagagt aaacagtgga agagtaaaac
     2161 aatataatgg ttaacataat attattaatt ttccctaaaa tattgaaaaa tattattata
     2221 taagttataa tattaatata cacgtagata tttattagtt agatttgagg ttggaaaagg
     2281 cacccaatac gctactatag agtagttaat agagatgcag gatacgccgc cctgccaaat
     2341 ctaattaaat taaaaagaga ggattaattc ctctcttatt gtttttttga gatactaatt
     2401 taatctatat agaaagattg aaggtcattt atactaaaag ttttcagtta tatacattaa
     2461 actaattaaa taagatattt ataatctata tgtgatacat attatatatt aataaaagaa
     2521 aaatatatag aaaatcctta taaaaattta aattgtaatg aataggaagt aattaaaaag
     2581 aatttttatt gatttttaaa aatttagtta gaaactatat cattatggta aaaaatgtat
     2641 tataatgttt agaaatatta taataaggag cgattaaaca tgaatctatc gaagaaaata
     2701 gaagataaaa gaaaagctaa acagagagct gaaaaagtta agaaagctaa aattgctaca
     2761 gctggtgtgg tattaggagc tgttactggt gcagtgagtg gagtactttt ggctcctaaa
     2821 tctggaaaag aaacaagaga ggatataaaa gatgcttcac aacaaattgc tgaaaagata
     2881 aatatgaaaa ctgtagacgt aaaaggcaaa gtatctgaga agctagagga taaaaaagga
     2941 aactttatag aatcaaagaa aaaaataaaa aaatatatag ataacaaaaa gagtgttgaa
     3001 aattctagtg aggaagataa aataatagat atagttgaac cagttagtgt tactgaggaa
     3061 taatatggac aatacaataa cgattaacat aagtataata tatgtattat tagctatact
     3121 tgcttgtatt gctttagttt atttaattat tgtacttgtt aaactacata agattttaaa
     3181 taatgttgga actatgttaa atgaaaatac tcaaaatata aatacaactt taaataatct
     3241 tcctaatgtt gtagaaactt ttggagaagt aggagaaaat atgaaagatg taacagaagt
     3301 agttactgaa gttacagcag attttcttgt tactaaagac agtgtcaaat caaatatgga
     3361 tgttatagtt gatatattga ctataattaa aaacattttt ctagataaaa aataataagt
     3421 taatataaaa taagcctata agatataatt taaacgacct taaaatagca tttataaggt
     3481 cgttttttat tagcttgatt tgacactatg tgtttttaat aattggtaat attcctcttt
     3541 atcatttgaa catatatatc tatgcttgtt gtttcaatta catccataag aacatcttta
     3601 cattcaagct caaaatcttc cattccttct aaatattcat catcttcatc aaaaaagata
     3661 taagaattat atagccattc ttcaaatctt tcttcaagta tatcccaata cgaactccaa
     3721 aataatccac aacctgatat ataagatgct ctactttgat ttatataaac ctcatttaga
     3781 agcttttgta atctactgct ataaagaaaa tctgctcttc cactgcttga tattaattca
     3841 tttaaatctt ctattgacat taattcaact ttaccacttt tatcataagg agtataattt
     3901 tcatcaaccc atttatgtgg tttgttttct ctgcatactg ttgctatcaa ctctacaact
     3961 tttgttctta tcattttttt atcctaactt gtttattttt tataaaataa tcatgatttt
     4021 ataatttatc tatttcttgt aatgctaatt taacagtttc atatctatca gcaccattta
     4081 ttactacatc accttttaca agtttattag cttctccacc tacaacataa acctttttac
     4141 ctaaaccttg cttataacta gacgcctcaa ttattaaaga atctttcaat tgccaatgta
     4201 aaatctgagc agccacttta tcagcatcac ctgtataaac gattacattt tcatacactt
     4261 tattttcccc tcccccttga gaatttgata tagatttgtt tagtatacct tctgctatca
     4321 atttagcaac tttatcttta ttattaacat aataatctgt atctgcttta ctatctacaa
     4381 aacatacttc tattaatatt gctggtgcaa tagtatgatt aagccaataa agacctctaa
     4441 catcagactt tgcaccccta tctttgaata ctgtagctaa cctagtattc actctttctg
     4501 cataggtttt gccattatta gtcttatata ttgtttctgt ccctactgta gttgaagttg
     4561 tagcatttga attaaaatga atctgaacag ccaaatcagt ttcctgttta tttgctatag
     4621 cacattggtc tgctaaatga ttacttgatt catcaactct tcctgtataa acagtagctc
     4681 cacctatttt aagccattta acaattaagt cattcagtat tcttgtttct ttgctttcgt
     4741 ttatataccc aacagctcct gtaccttttc caattaaagt gtgccctggt attattacta
     4801 ctttcaaact aacatctcct ttacaattaa atttaacttc tatttaatat atgcataacc
     4861 tagaattttg tttcttttta tatcttatac ttttattata acccattttg taaaaatata
     4921 gaatattaag taaataatgt taaaattata attttgtata taagacatta cttgattgca
     4981 ataattttat agcatattca tctattctat atccagttct ataatatata tgtttaattc
     5041 cagcttgaat tatagcctta gtacaattta agcaaggaaa gtgagttaca taaatagagc
     5101 aatttttaac tgaaatacct tcttttgcac aataataaag ggcattttgt tcagcgtgaa
     5161 tggttctaat acaatgtcca tctctcattt catgaccaac ttcactacaa tgcttatctc
     5221 cagaaatact accattatat ccagtagaca ctattctgtt ttctgaattg acaattatag
     5281 ctcctacata agctctatca caagttcctc tttcagctac tgtttcgcac agtctcataa
     5341 aatattcttg ccatgagcat ctattttcaa gttttttatt caaatcatat acctccaaaa
     5401 tttatatcta atatataaga tttatacctt aaaaataata ttaaaaacaa atttatacga
     5461 taaataaaat ttattaatac tgtttttagt ctaaattatt tcattttaaa ttaaagttac
     5521 aaggaatcta aaattatata tatctttctt cgtaatatga atgttacaat ataaaaaact
     5581 gtctcaataa aatagagaca gttttacagt caaagtttat aatacaagtt catatttttc
     5641 tttaaattct tttacagctt cgggccatgc cttttgttct gtaatacctt tttctttagc
     5701 tattttaatt gcaatctctc ttatcattgc agcgccttct aatattccca tttttaatct
     5761 cccttcaaat atctttttgt atagaatata aatagtgcta agatttatta catgctgcat
     5821 atacaatatc tatacaacac ataacttgta aattcctttt attttcatac gtctttaacc
     5881 gacatataat tatattcaat aagttttaaa attatgaact caattataat tatttttatt
     5941 tttttagaat ctaaacacta aaaattgtag gtaaatttgt cttatgcctt tataaatatt
     6001 tctacagttt taattactgg acatatctat ttttattata aaaagcgctt aaaaatcgag
     6061 aatatccgca taaaaactat atataagcaa aacgattaaa ggaaaaagaa gaaatttact
     6121 tgaatgttaa aatgcgttgc ttgaagcaat gggcagtttt gcttataata tcggtaacaa
     6181 ctgaaagaaa ggtggttagc cctaatgtta agcgaaaaca ttaaaacaat caggaagtca
     6241 aaaggacttt cacaacaaga acttgctata aaactgaatg tagtgcgaca aacaatatct
     6301 aaatgggaac aaggactgtc ggttcccgat tctgatatgt tgatttccat atcagaggtg
     6361 cttgaaacgc ccgtaagcac tttacttgga gaaactattg ttgagtcgga agttgataac
     6421 ttaaaagtga tttctgaaaa attagagatt ataaacttgc aacttgcaca aagaaaaaac
     6481 atgagaagaa aaatgtttca ttggttattt attttattat gtgcagtcat attaatagtt
     6541 tttgtggtct tagggagact aaatagtcct tacttggatt ggaattatac cgaccctgaa
     6601 accgctgttt ttggagtagc ttttcatgct tttgagtggc tatttgtcag attagtaccg
     6661 attgtcctta taggagcaat tattggaatc tttttgacac gtaagaaaat atgaagtaac
     6721 tctgcttttt ataatacagc aagcgttcct taaaagcgtc attctacatg gcaatcgagg
     6781 acgactatgt aatgaagaac ctttttgatt tccaactaag cgaagttatt gaggacgaca
     6841 gtaggcccaa aaccgcatta agtaaagtac aggaagcaag actgctggac ttatactctc
     6901 atgcgtcaga tgcaggaaat gcgaggtctg gtagcatgat ttacaacgat ttgtacaact
     6961 attgcgagta gaaatatatg gagataagta ttatctacaa agtcagaaaa gaaatgattt
     7021 gataatttac ccatgttata attattgatg tgaaatcaat aaatcaaaat tcctttttgg
     7081 gatttaacaa taaggaaaaa gtgaatgact tttgcaagga ggtgttaata tcagacaagt
     7141 aaagtctttt gtttttccag ttatatcctt aatattctta gaccaaatta gcaaagttct
     7201 tataggatta ttcttaatgg actttgaaat tgatataatt gggaaatttt taagattcaa
     7261 tcctgttcaa aatacaaaat taagtctctg ctatctaaca aacggagcac aaaaataaaa
     7321 attaaatata aagcacagtt aattttgatt aaaaagttga ctgtcttttc ttttgtagaa
     7381 atttaagcat aggtaataaa gaaatgactg catttaagca ttatgtatat aattggaggc
     7441 aataaaaagc cagcaaagcc cataaaatag agctgtgcta gcaacatgat gaattataag
     7501 aagataatca aaaacttacg ctttatttta atttaaaaaa atgattactg taaagaaatc
     7561 attttttatt ataatcactg atacatcaaa tattctaaat aaaattttta tttatctgga
     7621 attgtatatt ttttctataa tattaactac agcgtacatt gcccaagcac agatagccaa
     7681 tacaaatact cccatcatta ctaaatctaa tttaaatact tgagaaccat atactatcaa
     7741 gtagcctatt ccatatcttg aaactaaaaa ttctccaact attacaccta cccatgccat
     7801 accaatatta attttagtta aatttattaa atttcctgtg tttgcaggta atatgagttt
     7861 aaataatatt tgagatttag tagctccaaa actttttaac atcttaattt tttcttcatc
     7921 tatattcata aaataattat aagctgaaag tatagtaaca acaacagaaa tcgttacagc
     7981 tgttacgacg attccttcta ttccagcacc tacccaaact ataattatag gagctaaagc
     8041 agtcttagga agagcattta aaactaccaa aaatgggtct aatatttttg ataatttttc
     8101 tgaccaccaa agagcaattg ctaccaaaat acctaataca gtacctataa caagaccaag
     8161 aacagtttca tatacagata ttccaatatg tttaaataat tgaccactaa atgcatattg
     8221 aataaataaa ttgtaaatat cacttggttt gctaaataga aatgtattta taacatttaa
     8281 gtcagctaaa agttcccaga ttacaataaa accaattaaa attaatagct ggtagaataa
     8341 tacatttctt ttttctcttt ttacaccttt aacatagttt atatatcctt cagatctttt
     8401 attaagcctc atgtgtatct agctccttcc ataatatgtc gaaatacttt tgaaaatcag
     8461 gaactttacg tgttttgaga ggcgtttttg ttccatccat gttaagttca atatcgtaaa
     8521 tattttttat ggtagctggt cttttagata gtattgcaac cttatctgat atgcttattg
     8581 cttcaccaat atcatgtgta accaaaatag tagacttatt ctcattctta ataatactat
     8641 aaacatcatc acaaactaat aatctagtct gataatcaag agctgaaaaa ggttcatcta
     8701 aaagtagaat atctggattt acagaaagtg ttctaataag cgcaactctt tgtctcatac
     8761 ctccagataa ttcttttgga tacatacttc taaaatccca taatccataa gtctttaaaa
     8821 ggctttcaac tctatctaaa gattttttat cttttttgcc ttgaatttcc aatccaatag
     8881 ttatattatc cattatattt ctccattcaa gcaaattatc tttttgaaac atatatccaa
     8941 tatttccagt aatctttata tcaccactag tcggttttaa aagattagta agaatattta
     9001 atattgtaga tttaccactt ccagaaggac caagcaaagt taatatttct ccttctttca
     9061 agttaaaatt gacatccttt aatacttcaa gctcgccttc cttagtgtag aagttcatat
     9121 ttatattttt aacttctact atgttgtcat tcattatgcc accccctata acttttagct
     9181 cgtatatatt atgttattaa caatatgacc tatttgtacc atttttcata aatataatat
     9241 aaatattttg tttatttacg tattttctta gtaacttgta cgtataaatt atagataaat
     9301 aaattataag gtaggggata aatttgagta acataataac gaatttaata gagtcaatat
     9361 ttactaatcc aataactata ttgtttttac ttgcaataac tgtgtattct gtttttaaaa
     9421 taatagaaaa taacagagta tattcatttg taagttcaaa attagacgaa atcaatagag
     9481 actataagac aagtgagttt tataaaaagg taagggatga ctactataca tatagtaaag
     9541 aaaatcctta tgcagacgta aatataactt catttataga ggaagttgta tctgatttaa
     9601 agcataataa tttgccattg ttagaaaaaa ttagaagtat aaaaaattca tcttcaataa
     9661 gtatattact tggggtttta ggtacgtttg ttggtctttc tacaatgctt ttatgtgttg
     9721 atactaaaga cattataaat tcacttcctt caactattag tagtatgcaa actgcattta
     9781 caactagtat atttggagtt gtattttctc taattatagg ttactttact aagataaaag
     9841 attgtgaaca tgttttgata caaataatgt taaaatctga aaatttacta acatctgaaa
     9901 taactcattt taagtcagaa agaatggatt taaaagtaga agaggtaaaa aatacaataa
     9961 aacaaataag taagtctata gaagctattg aaaaatttga taaaatatct aaagatttaa
    10021 atgactttaa tgatgaattt atcagtggta tagaagcttt aaaaagcctt ttagaaggtt
    10081 ctcaaagttc tattaagaca tttgaccaga gcgtaagaaa attagataaa cagtttaata
    10141 ttttaaatat aaaatttgta aagctttttg ataaatatga taatcaagat aatataaata
    10201 aagagatttt atttgatata aaagaatctt caaaaaatat atacaatgcc actgaaagcc
    10261 aattcaaaat tagagattat ataaaaaata taaatgcagg atttgctcta tatgaaagaa
    10321 gtgctcaaga cttattaact aaattaatga cccatgaaaa taaaatctct caaaatcaaa
    10381 aaatcctttt agatgaaaag tttaccttag atgactcaat aaaaaatctc tcaagtatta
    10441 ttgaaaactt ttctaatgac ctacaagtta aactggatat gatgtttgaa aattctttag
    10501 atattcaaga taagttagat gttatgttta ataactcttt tatgaatgat gaagttcctc
    10561 ttgatagtga aaaattattt aaggatgatg ttaataatgt atttaatcct tttagtgaag
    10621 aaatttatga gatagaggat aaagaaataa aggtcatagg tgaggatgag ttaaatgaat
    10681 aataaatata taagaactgt taacagggaa tttgaaaaga gtagcttttg gccaacattt
    10741 acagatttat tatctactgt attgatggtt gtaattctta tcttatttag ctcagaaagt
    10801 atttcaggtt ctgttgaaca agatttagct aagaatgtca atgcttctgt tgaagaaact
    10861 tttaaaaaaa gtggaatacc tgtcaaggta gataaatcta atgggcaagt aacttttggt
    10921 gaaaaaacca tgtttgatat agatagtgat gttttaaaac cagaggctaa agaaatgcta
    10981 aaaatgtttg ttccaaagta catagagact atttataaag attatggtga ctatatatcc
    11041 aaaatagtta tagaaggtca tacagatgat gtgggaagtt atatatacaa cttagattta
    11101 tcgcaaagaa gagcatatag cgttgctaaa tttatagtgg gagatgaaat aggtgactat
    11161 aaatacaaag ataaagtgac taagcatatt attgcaatag gaaggtcaaa agctgaactc
    11221 atcaaaaatg gtgacaatag cgtgaataga gatgcatcta gaagagtaga actaaaatac
    11281 gaaataaata ttaatcaaaa taaataatta aatttttata aaaaaaaaga aggcagttgg
    11341 tgtgagcttt aagccttctt taaggaaaaa gtttatttat ttttgttgat acttaacata
    11401 ttatagtttt tagaagcagt ttgcaatata ttaaacgtaa atggtcgttt aaaatgcata
    11461 actggatact actgatgtaa aatatttcat tttatataat ataaaaatta tacagtgtca
    11521 attttctata ttattgtact ataatctatt atttaaaata ttatgtaaaa aaatatcata
    11581 aaaacgcata tcatgttata attactagag tattatgaat atggaggcgt agtttgtgat
    11641 agaaataagt ataaaaaata aaaaaaattc taaaattaaa actttgatac ttttattgat
    11701 agtatctata tcgatttatt taactggttg tactacatca gataatggaa ataatcaatc
    11761 aaataataat gattctttgt ctagtagtat atcaagtgat aagaatgtaa aaattcattt
    11821 tattgacact ggaaatagtg atgcaatatt gattcaagat ggtaaaactt ttacattgat
    11881 agatggggga gataatgatg atgagggatt aatggtagat tacctaaaca atcaaggtgt
    11941 aaaagatatt aaatatctta tagctaccca ttctcatgca gaccatttag gtggacttga
    12001 ttctgttgtc aaaaacttta atatagaaaa tgtttttgta tcgaatggtt cagcagaaac
    12061 aaagagttat agggacttta taaatgcttt agcaaataag ggtttatccc caagtgtacc
    12121 gcttgaaaat aataagttct atttagaaga ttcttatttt gaagttctaa atacaaatgg
    12181 gggagatact actaatgaac aatctctagt ccttgtatat actaatggga atgataaagt
    12241 tttatttaca ggtgatgctg aagaaggtac cgaaaaagaa atactaccta agcttgagaa
    12301 agtagacctt ttaaaagtag ctcatcatgg ttctcgtagt agttcatctc aagagttttt
    12361 agataaagta aatcctgaat atgcggttct tttagtaggc aagggtaatt catatggtca
    12421 tccacatcag gagacaatga ataaattaaa aaaaatggga gtaaaagtac atagaagtga
    12481 tgagtgttca gatataatat ttgaatcaac aggtgatgga gtatttacaa gttgtaaaga
    12541 tggaagttat aataaaggcg ttagagaaga tggaaactct ggaaaatcaa acagtaatac
    12601 aagtaaaaat gattctttta aaaataaaca aaatacatcc aattcagaag aaatagtgta
    12661 ttttactcca aaaggtaaga gttatcactc tacaaaaaat tgtagtgggc tttcaagaag
    12721 taaaaaaata ttatcaggca caattgcaga aagtaagaaa aatgacccat gtgatatatg
    12781 ttatggaaaa taacaaaaaa acaaccaatt tatctataaa gcttctgaac tttaaatcat
    12841 ttaaaaaata aaataaatgc ataaaaaaat aagctataat caatagataa cacattttat
    12901 ctatacgaat agcttatttt tttaagtatt ttttaatagc tatttaataa ctctaaatac
    12961 accagttaca atacctacaa tttcaacttc tgagtcattg agcataattg gttccataaa
    13021 atcattttct ggctgaagtc ttattaaatt tccttcttta aaaaacctct taaccgtagc
    13081 agattcacca tttataagtg caactactat ctgagaattt aaggctgtat tttttttgtc
    13141 tactacaacg taatcttcat ctaaaattcc tgcattaatc atactttcgc cttttactct
    13201 taatacaaaa ttgttactgc cctttactaa actggcaggg aatggaatgt attcctctat
    13261 gttttgttga gctaaaatgg gttctccagc tgttatttga cctactaaag gaagctctat
    13321 tatttcttga ttagctccag aaacatcatt tactttacta cgttctaaaa cttcaatagc
    13381 tcttggttta gtagggtcct ttcttatgta tcccagtttt tcaagtttat ttagatgaga
    13441 gtgcacagtt gaagtagatc ttaaccctac agcagtacat atttctctta cagcaggtgg
    13501 ataacctttt aatatgattt gagactttat aaattccaat atcaagactt gcttttcagt
    13561 tagatctaaa tacataacat cactcatttc caaacatatt ttgtttttat ttccatacac
    13621 tttatatttt taattataac ataatccatt tatatctgca aacatttgtt cctgattttt
    13681 aatcgtcctc aatccattca aaattcttga ctatatcacg ttttacattt ttcttatgag
    13741 ctgcataaag ctgagtagtt gtgacattat catggtcaag taagttttga acatcatata
    13801 tagaaaatcc tgtttggatt agagaagttg cagccgttgc tcttaattta tggggactat
    13861 atccattgtc tctagtagta tcaagtggaa tagatgtata tttttttacc agtgttctta
    13921 tagcctttgc tgtaattctc ttattttgaa gagacaaaaa taaagcatct ttttcttcat
    13981 catttaatag ttcatctctt gttctttcgt tttgcaaata atcttttatt acatgttcac
    14041 aagtatgatt tataggcatt aaaacttctt tcccacgttt tctatatatt ttaaattcac
    14101 ctcttgaaaa attaaaagag gagatattga gttctctaag ctcatttaat ctaagcccgt
    14161 atgtaacaaa taatgctagt atagctttgt cacgtaattt agtttttctc caatatacct
    14221 tttctttctc tgtaagccct tcacctgttt ctactgattc aagcatctta gcaacttcat
    14281 ctatctcaag gcgcttaata gcatctggct gaggtttagg aagttttatt ggattgaatc
    14341 catcagttat attattatct atctgagagt ttctgtataa gaatttaaat agagtagaga
    14401 tggatgattt ttttcttgct aaagctctat tgttattttc aaaaatcaat gtgttttttt
    14461 ctgtattttt gtaatatcta ctgcaataat cacctaagaa taaatttata tctcttgatt
    14521 ttattgtatt aaaatcatct tctgtaatgt cttttacaca atctgcattt gttaattctt
    14581 tggtttcaat caaatatgaa caaaaaaaat taatatcttc taaataagca agtcgtgtag
    14641 aaactgcaac agaacctttt aaatatataa aataatcctt cataaataca ggaagtttat
    14701 tttccaaaag tagacatttt tctatgagtt cattttcttt gataacaata ttatcaggtt
    14761 tatctgattt attatgtact tttataattt tcttatcatt attcaaaatt aaacctccta
    14821 aaactaaaat ataaatcttt tatattattt tttgatattt ataccaagtg agtataaata
    14881 tttaatttaa tcatttttta catttttaag agattagcag tgctttagat gaaatcatca
    14941 ctaactattc cctaaatcca catttaaaga ctagttgaat ttaagtactc ttttttattt
    15001 ctcaatatat ttatagaaat attttaaaat atattgagaa attttttatg ctctactaaa
    15061 atctttttta tataatattt ttatatgttt ctaacgaaac caaatattag taaaatatgt
    15121 atttatttaa ctaaagtttt taaatgggct gactaagctt aaaatatagg atattatgag
    15181 agttactatt gaaaaaataa accctattgc cataaagaaa cttataaata tgttatactt
    15241 aactattaaa ctggatatat tcaagttatc aaatccaaat aagtatgtaa ttgaacttat
    15301 tacaaaaata actataacta taaagctcag accatttaag ctatttttta aatcagcact
    15361 actaagtgac atatgtgtag atatagaata cattaaaaac ataaatataa aatacttcaa
    15421 tgaatataca ctaggtgtta acaacattat tcttataaaa ttggaaatat cacctaaaat
    15481 aatgtgtata aaaccattta tatttaaatt attaatcata cttacatata actttaaatt
    15541 tatattttga gtcactttca tataactatc tggcagtaat atcttaaaaa ttaaaataat
    15601 cattattgtt ccacctataa taggtgcaat tcctataaag aaatttccta tactttgata
    15661 aagattatct tttttatagc tatgacttac atatcctagt ataccatcat ttttactttc
    15721 tattggtctg aaaaacttaa ctgaatttat tttatgcatg aaaattaaac acattatcaa
    15781 atgactcaat tcatgaacaa atgttcctat agctccagtt acaataattc cagtttttcc
    15841 aaaagatgaa aagataaatt tattatttag attttctgta atgctaaaaa tcaatccaaa
    15901 tacaataaat attcctatga aacaaaaaat atttattaca cttattttta aaatttcgat
    15961 tatataaatc ataagttaag tcctcatgta aaagtattta actactctac ttcatatcca
    16021 ttacagctta aaattttaca agcattttct atatcctttt cttttactaa gatatagtct
    16081 gtatcatacg tagaaattgc aaatatgctt attttgttgt ctgctaacaa actacttaac
    16141 ttagataaaa ttcctacaag tgaaaagtct aaaggaccta gtatcttaag tattctccac
    16201 tccttttctg acttgacatc agaaggaata ttattattta aacatacaac acttaattca
    16261 tcatcagttc tagttataga gtaaaacttc tctgtatcta tccatgttgg tattttactg
    16321 tcattattta atctacatac tgcatactct tctaccaata attttaattt cataatgtat
    16381 atttcctcca atcttatttg tttacttaag attatacatt aaaagttaca taaaataaaa
    16441 catataaagt aaaaaaggtt cactatagtg tcctatttct atagccaacc tttaaaactt
    16501 aattaaattc taataaagag atatattatc taggttcaat tataagttta atggctgttt
    16561 tcttatcacc ttcgatttct atatcagtaa atgcgggaat gcaaactaaa tccattccac
    16621 taggtgcaac aaaacctctt gctattgcaa ttgattttat cgcttgattt agagctccag
    16681 ctcctatagc ttgtatttct gcaacgcctc gttctcttag tactccagcc aaggctccag
    16741 ctacagaatt aggattagat tttgatgaaa cttttagtac ctccatttca acatctcctt
    16801 gttaatttgt taaagtatcc attacctaaa gtactaaatc ataattgcca tttactaatt
    16861 acaatcatca tttaaagtat acttttataa aaatatactt ctataatcgt tttaagaaaa
    16921 cctttatttt ttttaaccat tttattatga aaaaactaca aatttcttta tattctataa
    16981 gcattttcca atatttctaa attttttata tctttgagct ataatttcct ctttatccat
    17041 atctttgtaa tgatttaatc tttctaaaat gtaagctttt atttcttttg aaacagcttc
    17101 tacatctttt tgtgctcctc caagaggttc ttttataatc ttatctatta tttttaaatc
    17161 atataaatca ttacttgtaa gcttcataac atcacaagct tctttagctt tagatgaatc
    17221 tttaaataga atactagaaa gcccttctgg agaaatcaca gaataaactg aatgttctaa
    17281 catacataca tcatttccta ctccgatacc taaagctcct ccactaccac cttcaccaat
    17341 tacaaaagtg attactggaa cagaaagttt actcatttca agtaagtttc ttgcaatagc
    17401 ttctccttgt cctctttctt ctgcttctag accacaaaaa gctcctgatg tatcaataaa
    17461 cgttattata ggtctattaa atttttcagc ttgtttcata agtcttaatg cttttctgta
    17521 tccttctgga tgaggcattc caaaatttct ttttatattt tcttttgtat ctcttccttt
    17581 ttggtgtcca actatagtaa cattaaactt tcctatctga ccaattcctc caaccataga
    17641 agggtcatct ttaaaaagcc tatctccatg aagttctaaa aaattagaac aaatatgttc
    17701 tatgtattcc aatgtcgtag gtctctttat atctctactt agtgttacct tttcatatgc
    17761 tgatagatgt gaaaaagcat cttccttaag cttttccaat ttctcattaa gtgaatttat
    17821 tttatcactt aaatctatat tatttgcctt agaaatagtt attaattgtt taatatcatt
    17881 ttctaagact tttatttttt cactattatt ttcaatcaaa acagttcctc ctttatgccc
    17941 tatttcttgt gcatagcaag aatttgatat aatacttcct tcatttttct tctatctact
    18001 atcatgtcaa taaaaccttt ttcaagtaaa aactcagaag tttgaaatcc ttcaggaagt
    18061 ttttgattta ttgtttgctc tattactctt ggacctgcaa aacctatcaa cgtatttggc
    18121 tcagaaatta taatatcacc aagcatagca aaactagcag ttactcctcc agtagtaggg
    18181 tcagttagaa ctgatatata tggcaatgat ttttcttcaa gcttagaaag tgcttgagaa
    18241 gtctttgcca tctgcataag agataccata ccttcttgca ttctagctcc tcctgaagca
    18301 gaacaaataa ttataggtaa attattttca gcagcatact ctattgaata agttattttt
    18361 tccccaacaa tagaacccat acttcccatc ataaaatcag gattcattac acaaataact
    18421 gttttaattc catttattct tccataacct gtgacaacag cttctgactc ttttgttttt
    18481 tccttataag agtctacttt ttctttgtat ttaggaaaat ttagtggatt ttgaaattct
    18541 acatcagaat taaactccat aaaagttcct ttatcaatca ataaatttat tctttttctt
    18601 gctcttaagc cataatgtct tgaacatttt ggacatacaa atgaattttc ttctatgtcc
    18661 tttctaaata catgactatc acaacctttg caataggtcc aaaatttatc atctacacta
    18721 ttctttttaa agttgtcatc taaagaaatc gtaacatact tagattcttt tgatgataaa
    18781 aattttttta tcataatcta tttactcctt ataatgtagc aaattctttc ttcataaaga
    18841 catcttctat aaatttggta tgatgagtat cttctctaaa ctcctcactt gttacaagtg
    18901 ccttttgaaa ttctacattt gtattaatac cttctacaat aatttcgtct agagctctat
    18961 atattctact tatacattct tctctagttt cagcccaaca tattaactta cctatcatag
    19021 aatcatataa aggtggtata gtatatcctg catatacaaa agtatcaaat ctaacaccaa
    19081 aacctccagg taaatttaat gattctatct tacctggtga tggagcaaaa ttctttgatg
    19141 aatcttctgc atttattcta cattcaatag catgacctct aaaagtaata tcttcttgtt
    19201 taaaaggaat tttatcccca ttagctatag atatttgaag ttttataagg tcaagatttg
    19261 ttaccatctc tgtaactgga tgttcaactt gtattcttgt attcatctct ataaaataaa
    19321 agtttttatc tttgtcaact ataaactcaa tagtacctgc accgatataa cctactcctt
    19381 ttactatatc tactgcaatt ttatgaagtt tttgtctttc ttcatctgaa aggtatggac
    19441 ttaaagattc ttctattact ttttgatttc gcctttgcat agaacaatct ctatcaccta
    19501 aatgtattgc atttgaatgt ttatctccaa atacttgtac ttctatatgt ctaggatttt
    19561 ctataaactt ttccatatat aaatcactat tagaaaatgc tgctagagct tctgaacttg
    19621 ccatatcaaa atttgaaaaa agttcttctt cttttctaac gattctcata ccttttccac
    19681 cgcctccact tgaggctttt atcataacag gatatccaat ttctcttgca acttctaaag
    19741 cttcttcctt agttttcaaa acagattctg aaccaggaac aacagggata ttcaattcca
    19801 tcatagtttc tcttgctcta gatttatctc ccatcaaaat catttgttct cttgttggac
    19861 ctataaaaat aatattatta tcttcacatt gctttgcaaa ttcaggattc tctgataaaa
    19921 atccaaagcc tggatgaata gcatcacact ttaatttaag agcaagatag attatatttt
    19981 ctatattatt ataactctta cttatattat ttggtcctat acaaatagat tcatcagcta
    20041 tatatctatg aaaacaatct ttatctattt cagaatagat agcaacagtt tttataccta
    20101 gttctttaca tgttctgatg attctaactg ctatatcgcc tctatttgca actagtattt
    20161 tttttatcaa cttaaatacc tcctactaca atggttttat cttaaataaa ggttgattat
    20221 attctactag ttcttcatta ctaactaata cttcaattat ttcaccttta atttcacttg
    20281 ttatctcatt cataagcttc attgcttcta atatacataa agtgtcgcct tcttcaacta
    20341 catcgccaac tttaacaaag ctatctgcat ctggacttgg agaatcatag aatgttccca
    20401 tcaaaggagc tactactact gatagattct cattagatgt gacaggtgta tcgtttacaa
    20461 ctggcttttc taaagaaaga tccactactg attcttgttg tacacttaaa acaggtgaac
    20521 ttgtagattg agctttttta gatacttcta atcttaaatc gctactttca agttttacat
    20581 attctaagtt agttgagtct atggccttta ataattcctt aatttcattg atgttcattt
    20641 tgttaccccc ttgtattatt acctggtgct aatattatat cacaaaaaac aaatttataa
    20701 aagaaaaagt gctgactaga gaatcaacac atcaatatat cttttaattt taaattaaca
    20761 accagtaact tatatttgtt ttaattttcc attattaata taaattataa gtataaaatg
    20821 aataaaattc aatatttttt gcaaaataca agagaataca aattaatacc tcgggaattt
    20881 ttaagacaaa taccaatatt atgcaattta gacttcgctt tctttcaaat tagtatcatt
    20941 ttctttattt ttacatagga tgtactttaa tttagctatc aaaacattgc tatataggtt
    21001 aaaagttatt agaattgcag gaattataaa gtaaactcta gcacctataa aaccaaaaac
    21061 tactgtaata agtattaatc ttttatttaa agtaaaaaaa ggtatattaa aaatactttt
    21121 gtcggatgtt tctggagtat aagaatatat aactccaaaa atcaaagtaa gcatacaaag
    21181 tggaagtagt gtataacttg aaattattcc cagaaatcct atactttcaa aatatttgct
    21241 agcactattt gtataaacaa acatgtatcc atttaaatat gcgcatatac atgatataat
    21301 gccaaaagtt ccccctaagg attgagtgta ccaattaaaa aatttagatt ccatatacct
    21361 cacctcctaa aactgtatat ataatgatat gcatttaaat agtaaaatat atctttatat
    21421 gtttctgaat aaaattttgt taatttcatt aatttatgtt taagaaattt gaagtatagt
    21481 gtagtatata ttaatgtaga tgaagtttta tagtacttat ttcatagtgc ttaatcaagt
    21541 tatcttatta tggattcaaa agttgtttgt agggttttat attttgttga gctgaaaaat
    21601 ttattataaa tgaagggatg ttttcgcttt ggtagataca ttagaatttg gtcttaaaat
    21661 tttatttttt atattatcaa taatttggat gggtaaaata atgattttaa gaactgataa
    21721 gcaaatagta atcaatcctt tgcttattgg tatatctgca gtccttgtga tgttgcatac
    21781 ctcacagagt aacattgaat tttttggatt agatgtccaa tatataagaa tagttttgta
    21841 tataatatat tcactgataa ttttaatagg aatatgggct actaacagaa gaaatggaat
    21901 tttttagata atctatttct ataaaattta aaggttgcta gtaacaaatc actaatatta
    21961 gcgttctgtt actaacaacc tttattttga ttatacactt aaattgaaaa tagaatgatt
    22021 gaataagttg acagattatt ttacattgac agtaattaga acttcttgag atgtatttaa
    22081 atcatttttg tcgcttagta taacttttac cactgcttga cctgttttat tacctttaat
    22141 tatcatatct tcacatgaaa gtacgctctt atcacttaca gatacaataa aatttaaatc
    22201 ttttggaagg ttatcagtaa cttcccagta tttataataa ctatcaattt tcttcgtaat
    22261 tatttttctc aaatcaatac tttcaccttt tgctatatca acattatgat atttagagtc
    22321 cagtttatac tgattatctt ttgtatcaat aaaatttaaa tcgcaattta catccacacc
    22381 attatgagaa agagaattta ctacatcgtc atcaatcaaa taattattgg caagatttat
    22441 tgaatccata tcttttagac ttaaagcttc cttaggaacc tcttttatat tattattcca
    22501 aaaaataaaa ttgtctacat tttcaagata tgatattcct tttaaatttg aaatgctctc
    22561 accagttgca taaaattctc catctaaagc ctttatattg cttatagtca tctcatctgg
    22621 gtttatatat ctttttacaa ctgctcttaa atttgcatca ggaaaaatat ctttaagttg
    22681 attttcgctc aaaaccttat catttgaatt tattggactt aaagctgctg cagaaataat
    22741 aaatggtatt aaattagcta aattcatagt accctcccac ataaattttt tattataata
    22801 atttaatttc tatgagaggg ttctgtttcc ttgttatata tacctacttt cgtacacttt
    22861 attaatataa attaaaataa atttctacta ttaaacttat aaacatatta ctagttacgt
    22921 tttttagctt cacatctaaa tattcgcata ccttgtgaca taaatttgtc ttcatactct
    22981 gttgtaacat tattttcata ctcactattt cctaaatcaa gagaaatatt ctttaatagc
    23041 caattatttg cagcaatttc atttaaacta aactcgaata atttttcatt atctgtttta
    23101 aagtgaattt cgccatcatc ttccaaaacc ctattgtaca tttctaaaaa tccagaatga
    23161 gtgagtcttc ttttactcca tctattttta ggccatgggt cacagaaatt tatataaatt
    23221 ctcgataatt ctttagcttc aaagtaatcc aaaatattgc ttacatctcc ccataaaaat
    23281 agtatattat tcaaattaga agcatctgct ttttcaacag cctttaaaag aacttcttcc
    23341 ttaagttcca tggcaatata atttatgtca gggttctgct tagctaaagt tgttataaac
    23401 ttaccttttc cagtcccaaa ttcaacatgt attggattat catttctaaa ctttaaattc
    23461 cacttgcctt ttaatttgtc tatatcgtct cttaaaacat attttgtata acttaaaagc
    23521 ttttcatctg cacctttttt tcgtcttctt ctcacaataa ttctccttac atataaaaaa
    23581 ttagtaaaat acatttttat tatacattat ctcaccaaaa aataaaaaga actctcttaa
    23641 aatagaaatt tatttctata aagagagttc taaacttact aaaaacttaa tcttagtggc
    23701 accctgaaca accagagcat cctcctccac cttgatcttt catattttca ggaataactc
    23761 taaatccaaa tcctgtatct tctattatta tatctccata ctgactatat tcatcagagc
    23821 tcattacaaa ttgtaattct ccaacttcat aagttaagtc atcttctttt ttctcatcta
    23881 aagctaatcc aaaagaagga cctccacaac caacacctgc aaagtatact cttatattat
    23941 taggtttatc ttgattgtct tttaagatac tttttaaagt atcaatagct gtttctggta
    24001 aagtaatttt catcaaatca ttccctttca aatattttat taaaacaata tctattatat
    24061 acccatacaa ggtacataat caattagttt ttgcatattt tactaaaact tctacctaat
    24121 attacctaag gctttaaaat attttatata atattttatt accttaaata aataccctat
//
LOCUS       DAMJXI010000055        24110 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.057, whole genome shotgun sequence.
ACCESSION   DAMJXI010000055 DAMJXI010000000
VERSION     DAMJXI010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24110
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.057"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            45..800
                     /locus_tag="PC465_002750"
     CDS             45..800
                     /locus_tag="PC465_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2650036.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQVLLNKHNLSNLAEHRRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLRKCLRYKRDFLENLLEGVSLDLKKYLDVQVKFLSGGQRQSLSLIM
                     SCLTNPSVLLLDEHTAALDPKTSNEVIELTDKIVREKNITTLMVTHNLKHALHYGDRL
                     IMLHKGEVVLDVKGKEKEQLTVEEILEKFEYAV"
     gene            931..1953
                     /locus_tag="PC465_002751"
     CDS             931..1953
                     /locus_tag="PC465_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2650037.1"
                     /translation="MINKKRLASLILAGALSISMLTGCSQGGDSGNSKQESNSKGKEV
                     KKIGITQLVEHPALDATRTGFVKALEKNGFKDGENIDIDFQNAQNDMPTTQSIASKFA
                     SDKKDLIFAISTPSAQAAFNATKDIPILITAVSDPVAAGLVKTLEKPGTNVSGTSDFV
                     SVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKNGFKVVEKGITTSNE
                     VNQGISSLVGKIDVLYVPTDNLVASSMPIVSKIATENKIPVIAAESGPVEKGALACQG
                     INYEKLGYKTGEMAVKILNGESVSDMPVATSDDTDIIVNEDILKALGMEKPSNENISY
                     VKTKQE"
     gene            complement(2117..2674)
                     /locus_tag="PC465_002752"
     CDS             complement(2117..2674)
                     /locus_tag="PC465_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDF2650038.1"
                     /translation="MTEKEKMLSGKGYYANDELLVKEREYCKKLTRLFNNTLEDEYEK
                     REDILRQLFGSVGKQINVEQNIRCDYGYNIHVGENFFANYDCIFLDVCKIEIGDNVML
                     APNVQIYTAYHPIDAQLRNSGIEYGSPVKIGDNVWIGGGVIITPGITIGDNVVIGAGS
                     VVTKDIPPNTVAVGNPCRVIKKIEE"
     gene            complement(2680..3756)
                     /locus_tag="PC465_002753"
     CDS             complement(2680..3756)
                     /locus_tag="PC465_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HDF2650039.1"
                     /translation="MSLYVDIEKDLSSFKLKVEIKQEKGTLGFLGESGSGKSMTLKCI
                     AGLEKPTRGKIVLNDRVLFDSEKKINLSTQDRKVGFLFQNYALFPHMTVSQNIELGLL
                     KLSKSEKKEIVARYLDILKLNGFEGRYPWQLSGGQQQRVALARALATSPDILLLDEPF
                     SALDHHLRSNMEKELMNMLKDYKGDILFVTHDIEEAYRVCDDIIVYNKGEGLPKRPKK
                     ELFESPKYLIEAKITGCKNISKLNRLDKNTIYATDWGCELTLNREIGDNIEYVGIREH
                     HIKVLDSNEDLNEKLCFELINIVENPFTYTIYVRKTDLSNECVPIQIELEKSKMRFKK
                     GDRIYLNFPQEYLFCFRYNYNKKE"
     gene            complement(3757..4440)
                     /gene="modB"
                     /locus_tag="PC465_002754"
     CDS             complement(3757..4440)
                     /gene="modB"
                     /locus_tag="PC465_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HDF2650040.1"
                     /translation="MGTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLI
                     DGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLNFDRTLIFSWTATVISAVVVSFPM
                     MYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEF
                     GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQ
                     QKIIGKRCG"
     gene            complement(4589..5401)
                     /gene="modA"
                     /locus_tag="PC465_002755"
     CDS             complement(4589..5401)
                     /gene="modA"
                     /locus_tag="PC465_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2650041.1"
                     /translation="MKKILGILGLVACLTLGTVGCNSNEDKKDDGKQEKTTKSSDSVE
                     LNISAAASLKEAMAKIEEEYKKVDSNVKLTVNYGASGSLQQQIEQGAPCDLFISAGQK
                     QMKALDEEKLLVSDTMKDLVKNDLVLISSADSSVSGMKDLTTDKVKKIAVGEAESVPA
                     GKYADEVLTNLNLKDKLKDKLVFAKDVKEVLAWVQSGNADVGFVYFSDTVNNDKIKVV
                     EKTDEKTHSPITYPVSVIKASKNVDAAKKFEEFLLSESGQKIFEEFGYKKVE"
     gene            5594..6523
                     /locus_tag="PC465_002756"
     CDS             5594..6523
                     /locus_tag="PC465_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2650042.1"
                     /translation="MDSLSSLTPVEVAELLKITKNTVYELIKRGELPSYKVGKKIRVD
                     TKDVEEYINSQKTGKVKDTHFNNKNIDINNNFKIIISGQDVILDILARSVEKKLDGIS
                     TFRSYIGSYNALYELYNGRVSIASSHLWDFETDEYNSTFVKKLLPGIPCVLINLAYRM
                     QGFYVAKGNPKEITTWEDLTKPSITIVNREKGSGTRVLLDGKLRLLNFNGKHIKGYDN
                     EELSHLGVASTVSRGIADVGLGNEKAALQVNNIDFIPLHKERYDLVIKKEDLQNPVYQ
                     TIINIINSPEFKAELQGLGGYDLTDTGKTIAKV"
     gene            complement(6684..7133)
                     /locus_tag="PC465_002757"
     CDS             complement(6684..7133)
                     /locus_tag="PC465_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650043.1"
                     /translation="MKNKNNKDKNMLNIKVLRVLGVLLILFDYTGDTLNFYNFFAKPL
                     VSGNLYKTTGTDCIVFLLFIVECVYLVGRYILKVKINWSEIIENEKGNFINNLLVEKI
                     QEESNIVYNLLNSYVLPHIYKKARGLMFKTYHMLIYIKEKYYYVNIY"
     gene            complement(7336..8316)
                     /locus_tag="PC465_002758"
     CDS             complement(7336..8316)
                     /locus_tag="PC465_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2650044.1"
                     /translation="MKNSFKNCISLRNKFIIISIVFLLILLIVSYIFGKLVYNSSVGL
                     EQLIKNEDIVKIFSERKDKPLEKLKNYKTSELMIQSSNNYKLESLFITSNIKTRDTMI
                     LVHGIGSSYYEMLKVAYRYLDKGYNVLVYNQRNTGNSGGDNYTFGLYERYDLDSLVKF
                     VKNKFPEGRLGVHGFSMGAGTAAMHSEINSKDDKVDFYILDSPYSEMKDAIRMGVLEK
                     RIPDILINYVVTCGDLYNKFKSGFWYSDVKPYESVEKSNVPILFIHGTKDTVCNYQNS
                     KKMYDLVKHDKKDLWLIEGIGHVDGFEHDSTVYFNKIFKFIDSNVLSDKS"
     gene            complement(8521..9381)
                     /locus_tag="PC465_002759"
     CDS             complement(8521..9381)
                     /locus_tag="PC465_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HDF2650045.1"
                     /translation="MAMKWRDYADDVNLFEDFDKTIKPLTDEQRRKNINTLIAYFSKE
                     VPSKIYNLSNDEIKPRDILRGLLNVYPPKEIAPEILNMLHNLLLIECEERELVDVNDI
                     EEVEEGIAIWRGNITNLRADAIVNAANNKLLGCLQPLHLCVDNEIHSCAGPRLREDCD
                     KIIKKQGHLEYTGDAKITRGYCLPAKFVVHTVGPIVSGGQPSKEQEKQLLHCYKSCLN
                     TIKEIDEIKNIVFCGISTGVFGYPKKEAANLAVSRVRLWLKENPEKNLKVVFNVFTEE
                     EEEKYRRIFK"
     gene            complement(9698..11026)
                     /locus_tag="PC465_002760"
     CDS             complement(9698..11026)
                     /locus_tag="PC465_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF2650046.1"
                     /translation="MEKFSVVIAGGGSTYTPEIILMLLDNLDRLPLRAIKLYDNDEER
                     QNKVAKACEILIKEKDPNIEYLATTCPKEAYTDVDFCLAHIRVGKLEMRELDEKIPLK
                     HGVVGQETCGPGGIAYGMRSIEGVLENIDYMEKYSPNCWMLNYSNPASIIAEAVRRLR
                     PNSRVINICDMPIGMEHNIARIAGLKSRKHMDIRYFGLNHFGWYTSIKDKKGNELLPK
                     LVEHIKEYGFINGEEGMKNDKKDSWFETNLFTKEIVKTDLTTIPSSYLKYYLFPDYVV
                     NHSDVNYTRANEVIDGREKEVFGSCALIEKQGHSKGSGLKIGIHAEFIVDLATALAFN
                     TQERMLLIVQNNGAIENIQDDAMVEIPCIVGKDGYEPLSIGKIPTFQKGLIEQQLAVE
                     KLVVDAWIEKSYNKLWQALMLSKTVPSATVAKELLDDLIEANKNYWPKLN"
     gene            complement(11174..11503)
                     /locus_tag="PC465_002761"
     CDS             complement(11174..11503)
                     /locus_tag="PC465_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2650047.1"
                     /translation="MVPEMEEKVFSIISEAGDAKSDVMMSLKEIKKGDYNKAKHLLNS
                     ASEKIQTASKYHLELLSNAMNSEDSGTDFLVVHSEDHYSNALFAHSLVSELVDIFEMM
                     DPRINKN"
     gene            complement(11527..12816)
                     /locus_tag="PC465_002762"
     CDS             complement(11527..12816)
                     /locus_tag="PC465_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2650048.1"
                     /translation="MEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSL
                     SMLFMALNNMLPEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNH
                     VEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIR
                     FPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDN
                     VFAVTIILFITQLLWFFGLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGF
                     YYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPSLFGINEPVIFGTPIVMNPY
                     MFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFAS
                     IILMTLIYYPFFKIMEKEELNKNAELATTLDDDSFDF"
     gene            complement(12832..13158)
                     /locus_tag="PC465_002763"
     CDS             complement(12832..13158)
                     /locus_tag="PC465_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2650049.1"
                     /translation="MNILLVCANGASTGVLVEKMKSFCSEHEKLKTKTINIEATSFEN
                     LKSYIEANDTDVVLVAPQIRFKEDDVVEACKNYKIAVGLIDTKHYGRMDAPSVMKSAI
                     ELYKNR"
     gene            complement(13293..13922)
                     /locus_tag="PC465_002764"
     CDS             complement(13293..13922)
                     /locus_tag="PC465_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650050.1"
                     /translation="MQDKILRDKKANDPWARMTTRNGFSADEIISSFQKAIRRNMVEE
                     ACEFAYELYISSPELEDKLWRRILTISVEDIGMGDPSAVIIINNLNQVRKEYSYADGD
                     RPLFFIHAIRYLCACEKDRSSDLLKNIIIKGFAMGKVPEVMDVALDKHTYRGLEMGRD
                     SFHFLNEASIVIPEKEVDNDYKERYLKILEKYKQEEVIDTAFKFNHWQY"
     gene            complement(14137..16794)
                     /locus_tag="PC465_002765"
     CDS             complement(14137..16794)
                     /locus_tag="PC465_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2650051.1"
                     /translation="MIYKKDKVMKVLESSYRENEKGITANQLSEKTGIARNNISTYLN
                     QLFNEGMVTKIKGRPVYYIPANLNLNKNELLDTQSELLGIKKGTKVENKIKKDSFETL
                     IGKEHSLRPIIEKCKVAMLYPTNGLHTIIYGETGVGKSMIARYMYDYSIDSGIRKNKA
                     PFVTFNCADYANNAQLLMGHIFGVEQGAYTGAESSRKGLLEIANGGILFLDEIHRLPA
                     EGQEMLFTFIDKGTFKRLGDATKERESKVLIICATTENPTSTLLDTFNRRIPMKIEIP
                     SLRDRTMIERMELVKNFFKEESKSISISIKVHKEIIKSLLLYDCKNNVGQLQNDIKLA
                     VANGYLRYKRDNKEPVYIEKKYFDKSINEVSDDYREKSIKADEVITHGIEYFVFTSLG
                     EEEVINYNDINIINAVNTNLNKSVEMNIADASLFNNVKFKSMCESIRQIIKEDEEIDI
                     SESIFKSMAIYIKSVLDKSSSTNNIDLNQIRRNNRSEFKTALKIVGIIENEFDLFLSI
                     ETVAYITLFIVQAKQDEQNKIVNNINIIVAMHGETTASSMVKAVGDIIGKCSAISFDM
                     KLDKSYDEVIVDFKNLINNIDNKDVLLFTDMGSLNSFDEIIKKEKKCGVRVIPMVTTL
                     TVLEAVQKANMGLPLNDVYNSITNTRKYYFGTNEIQNKENLSKTIIIASHVSEGVDNK
                     TRKILEEKMSRYLDGIDIISVPYKTEKDLSLNITKLKESSNIVAVINEQRINIRGIDY
                     ISKKDIDKDENINKLKNIIKISIGYDDVVEGLKTSLKSSNYNRIFKDIKYVSDELFLV
                     FNIEKKYDKVIGLMMHLAFMVDGLIGNTREIEKLDKEKTLDYHKSLSKIKDIVSQLDK
                     KYNIEINEKECYQILLILEYAEIIEKDYQ"
     gene            complement(17153..18097)
                     /locus_tag="PC465_002766"
     CDS             complement(17153..18097)
                     /locus_tag="PC465_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009082545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2650052.1"
                     /translation="MNREKILEIKNLKQYFHLDKSTTVKAVDDISFDIYKGEIFGLVG
                     ESGSGKSTTGKTIIRLHESTGGEVIYKGNCISDKKTYKFIKKDVNKSMQIIFQDSTSS
                     LNPRMTIADIISEPLKIQGICKNKTDRMNKVYEMLKLVGLDRSYANKYPSDFSGGQRQ
                     RIGIARALSVDPEFIIADEPIASLDVSIQAQIVNLFKKLQQEKNLTCLFIAHDLSMVR
                     HISDRIGVMYNGKLVELADSNELYNNPIHPYTKSLLSAIPVPDPRYAKSRNRIEYNSN
                     GYDCSNEKLLSWIEVSDGHFVYSSKSDINKYQQNLKVV"
     gene            complement(18090..19115)
                     /locus_tag="PC465_002767"
     CDS             complement(18090..19115)
                     /locus_tag="PC465_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2650053.1"
                     /translation="MEHLLEVNNLSVSFKVEEGEVQAVRNVSFNLKKGETLAIVGESG
                     CGKSVLCKSLMRILPYNGYIKNGEVLLKSSDLVKKSEKEMEDIRGKNISMIFQDPMTS
                     LNPTISIGKQIAEAVIIHQGISKSEAKKRAIELIELVGIDNPEKRFKQFPHHFSGGMR
                     QRIVIAIALACNPDVLIADEPTTALDVTIQAQIIDLIKDLQHKIGLSIIFITHDLGVV
                     ATIADRIAVMYAGKIVEIGTVEDIFYDPRHPYTWGLLGSLPTLDSQDDYLYNIPGMPP
                     NLLNPPKGDAFAIRNKNALKIDYEKEPPMFKINDTHSAATWLLHPDAPEVDVPVRVNC
                     GRVISNE"
     gene            complement(19190..20758)
                     /locus_tag="PC465_002768"
     CDS             complement(19190..20758)
                     /locus_tag="PC465_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2650054.1"
                     /translation="MKLKKLKVLSLVMILSLMAGCSSGGDKDKKADTPKDGKVLVYGS
                     NDYTSINPALYEHGEINSLIFNGLTAHDENNKVVPCLAKDWKFDEATNTYTFNLRDDV
                     KWHDGEKFTANDVKFTIETIMNPDNASEIASNYEDITKIDVVNDNTIKITLKAPNTAM
                     LDYLTVGVLPKHALEGKDIATDEFNQKPIGTGPFKLEKWDKGQSITLVKNSDYFVKEP
                     GLDKVVFKIVPDDKAKAMQLKSGELDLAQITPKDMSNFEKDEKNFKVNIMKTADYRGI
                     LYNFNSKFFKDKKAKGLPNALSYAIDRKAIVDSVLLGHGVPAYSPLQMGPYNNPDIEK
                     FEYNPEKAKQEIEKLGWKLGSDGIYEKEGTKLAFEITAGESDQVRVDMAKICAQQLKE
                     IGVDAKAVVVTETDWANQDAHLIGWGSPFDPDDHTYKVFGTDKGANYSAYSNPTIDKI
                     LQKARETEDKDEKLKLYKQFQVEMTKDMPYTFIAYIDAIYVGKPNIKGLTPDTVLGHH
                     GVGIFWNIADWTIE"
     gene            complement(20871..21782)
                     /locus_tag="PC465_002769"
     CDS             complement(20871..21782)
                     /locus_tag="PC465_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2650055.1"
                     /translation="MKPQYSDFEIVGENYILVAEDEHIETKKTLSKKIKELPYISIII
                     LSIIVIGSVFSSFIMTHEPTYMDLASSNLAPNKTFLFGTDSMGRDIYSMIWYGGKISL
                     FIGLFSTVISTVIGIVYGSISGSASELVDDAMMRFTEIILSIPSILIIIFVQAILGNS
                     NPVSMSIVIGITSWMNISKIVRTEVRQIRNSEYILAAKSMGGGFFYVLKQHLLPNFVA
                     SIMFMVVTNIGAAIGTESTLSFLGIGLPIEIVSWGSMLSLSEEALLSNRWWIILIPGI
                     FLVTTLVCITNIGNYIRKNNNKKSSNL"
     gene            complement(21766..22752)
                     /locus_tag="PC465_002770"
     CDS             complement(21766..22752)
                     /locus_tag="PC465_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2650056.1"
                     /translation="MLKDILKKLLQFILVMFLLSFIVFYMARLAPGDPLISYYGDGVE
                     RMSTQEKENAMKKLGLDEPIYSQYIKWISNASKGEFGISFKYKQNVTSVINDVYINTI
                     ILGGSGYILTFVLALLLGIFCTLHEDKLIDRIICKLGTITNCIPSFWVALVLILIFSI
                     NLSILPSSGAYSMGEESSILSRISHLILPLTVLILSHLWYYTYMIRNKLLEEIREDYV
                     LLCKAKGLNNRTIVFKHCLRNIMPSYISIMAISIPHILGGTYVVEKVFSYPGLGTLCF
                     ESAKYHDYNMLLVLCLITGALVVFGNMLAQIINNKIDPRMKYDRGDTNEATI"
     gene            23112..23513
                     /locus_tag="PC465_002771"
     CDS             23112..23513
                     /locus_tag="PC465_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2650057.1"
                     /translation="MLLKELYSKTMYTVEENFKENGLTHQQIIVIKLIAHNQELTISQ
                     LCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTTGFEFATNFKIKMQE
                     SFDDIFKNCDENELSDLVKNLRNILAKVKER"
     gene            23516..23914
                     /locus_tag="PC465_002772"
     CDS             23516..23914
                     /locus_tag="PC465_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03987 family protein"
                     /protein_id="HDF2650058.1"
                     /translation="MNYKLILAIVFITSALIFYTIGVFGERKAKILKKKHVIIFWLGF
                     IFDTLGTFTMSNIANSHTFEVKSALSQNLHSITGLLAIVLMLFHASWATFVLYKDDEE
                     KKKFFHKFSIVVWTIWLVPYFIGMFIGMAG"
BASE COUNT         7878 a         4113 c         2738 g         9381 t
ORIGIN      
        1 caaagctagt accaaaaata aatcagaaaa aagaggtgtt gtagatgtta caaattaaaa
       61 atctttcaaa gagtttccct aatccatatg gtgaacctaa tactatcttt gaaaatttat
      121 caatcgatat agaagatggt gaatttgtaa gtatcatagg tagtaatgga actggtaaat
      181 ctactttatt aaatataata tccgggctta taaaagaatc ttctggtcaa gtattattaa
      241 ataaacataa cttgtctaat ttagctgaac acagaagaac tcaaatagta agtagagttt
      301 ttcaagaccc aagtcttgga acttgccctt ctatgactgt tagagaaaac ttgtctttag
      361 ctcttaacaa aggaaaacta ttaaatctaa gaaaatgtct tcgttacaaa agagatttct
      421 tagaaaattt attggaaggt gtatctcttg atttaaaaaa ataccttgat gttcaagtaa
      481 aatttttatc aggaggtcaa agacaatcat tatcactaat tatgtcgtgc ttaacaaatc
      541 catcagtttt attacttgat gaacatacag cagcacttga cccaaaaaca tcaaatgaag
      601 taatagagtt aacagataaa atcgtaagag aaaaaaatat aactacactt atggttactc
      661 acaacttaaa acacgctctt cattatggtg atagattgat aatgcttcat aagggtgaag
      721 ttgtattaga tgtaaaaggt aaagaaaaag aacaattaac agttgaagaa atcttagaaa
      781 aatttgaata tgcagtttaa aataatatat ctattgtatt aaactcggct ttaaaataaa
      841 gttaaaatta caataattat ggttactttg taataattca tatgaatata tgaacatata
      901 taataataaa tttttgaggg ggatataaaa atgattaata aaaaaagatt ggcaagtttg
      961 attttagctg gtgctcttag tatatctatg cttacagggt gttcacaagg aggagactct
     1021 ggtaattcaa aacaagaaag taattctaaa ggtaaagaag ttaaaaaaat tggtataact
     1081 caactggttg aacatccagc attagatgcc actagaacag gttttgtaaa agcattagaa
     1141 aagaacggat ttaaagatgg agaaaatatt gatatagact tccaaaatgc tcaaaatgac
     1201 atgcctacta cacaaagtat tgcgagtaaa tttgcatctg ataagaagga cttaatattt
     1261 gctatatcta ctccatcagc tcaggcagca tttaatgcta ctaaagatat acctatactt
     1321 attactgctg tgagtgaccc tgttgctgct ggattagtta aaactcttga aaagccaggc
     1381 acaaatgtat ctggaacatc agattttgtt tctgtagaca aaggtttaga acttcttaaa
     1441 atatttgctc ctaaggcaaa aactatagga gttatgtaca atactagtga agtaaattcc
     1501 aaagtccaag ttgatgcttt aaaagaatat gcatctaaaa atggatttaa agttgttgaa
     1561 aaaggtataa ctacttcaaa tgaagttaac caaggtattt ctagtttagt tggcaaaata
     1621 gacgtattat atgttcctac agataactta gtggcttctt ctatgcctat agtctctaaa
     1681 atagctactg agaataaaat acctgttata gcagctgaat ctgggccagt tgaaaaaggt
     1741 gctcttgctt gtcaaggtat caactacgaa aaactaggtt acaaaacagg tgaaatggca
     1801 gttaaaattt taaatggtga atcagtatct gatatgcctg tggctacatc agatgataca
     1861 gatatcattg ttaatgaaga tatattaaaa gctttaggta tggaaaaacc ttctaatgaa
     1921 aatatttctt atgtaaagac taaacaagaa tagaaagata ttttctatat acgattaata
     1981 tgcctgtttc tataaattaa tttatagaaa caggcatata tttttatttt aatgtattat
     2041 ctatttaaag attatattta aatgctctta atttgtttgt ataaatttta cttgtataaa
     2101 ctttatacaa tcatatttat tcttctattt tctttattac tctacatgga tttccaacag
     2161 ctacagtatt tggtggtata tcttttgtga ctacacttcc tgcacctatt actacattat
     2221 cacctatagt aattcctggt gttatgatta ctcccccacc tatccataca ttatcaccta
     2281 tttttacagg agaaccatac tctatgcctg aatttctaag ttgtgcatca attggatgat
     2341 aggctgtata gatttgaacg tttggagcta acattacatt gtcacctatt tcaattttac
     2401 atacatctaa aaaaatacaa tcataatttg caaagaaatt ttcgcctaca tgtatgttat
     2461 atccataatc acacctaatg ttttgttcta catttatttg cttgccaact gaaccaaata
     2521 gttgtcttaa aatatcttct cttttttcat attcatcctc taaagtatta ttaaacaatc
     2581 tagttaattt tttacaatac tctctttctt ttactaacaa ttcatcattt gcatagtatc
     2641 ctttcccaga caacattttt tctttttcag tcatatagtt tactcctttt tgttataatt
     2701 gtatctaaag caaaataaat attcctgtgg aaaatttaaa tatattctgt cacctttctt
     2761 aaatctcatt ttactttttt ccaattctat ttgaataggt acacattcgt tagataaatc
     2821 agtttttcta acatatatag tatatgtaaa aggattttct acaatgttaa tcaattcgaa
     2881 acataacttt tcatttaaat cttcattaga atccaagacc ttaatatgat gctccctgat
     2941 tcccacatat tctatattat cacctatttc tctatttaat gtcaactcgc atccccagtc
     3001 tgtagcataa atagtatttt tatccagtct atttaatttg gatatatttt tacaccctgt
     3061 tatcttagct tctataaggt actttggaga ttcaaagagc tcttttttag gtctctttgg
     3121 aagaccttct cctttgttgt acactataat atcatcacaa actcggtaag cttcttcaat
     3181 atcatgagta acaaatagta tatctccctt gtaatctttt aacatattca taagttcttt
     3241 ttccatatta cttcttaaat gatggtccaa tgctgagaaa ggttcatcta aaagtaatat
     3301 atctggagat gttgccaatg ctctagctag tgctaccctt tgttgttgac caccagataa
     3361 ttgccaaggg tatctcccct caaacccatt taatttaagt atatctaagt accttgctac
     3421 tatttccttt ttttcactct tacttagttt taaaagccca agttctatat tttgacttac
     3481 agtcatatgt ggaaacaaag catagttttg aaataaaaat cctacctttc tatcttgtgt
     3541 tgataaattt atcttctttt cagaatcaaa tagaactcta tcatttaata caattttacc
     3601 tcttgttggt ttctcaagcc ctgctataca ttttaatgtc atactttttc cagaaccaga
     3661 ttctcccaaa aaccccagag tacctttttc ttgtttaatt tctaccttta gtttaaaaga
     3721 ggataaatct ttttcaatat ccacgtataa gctcaactat ccacacctct ttcctataat
     3781 tttctgctga aattccgacc aataatttag taataaaatc attgctatag atattgctac
     3841 aataatcata acccacatca tagctttatt catatctccg ccttcaacag caaaaaatat
     3901 agctattggc atagtttgag tttttccagg tatatttcca gctatcataa gtgtagcacc
     3961 aaattctcca agagctctgg caaacgacag caccaatcca ccaattattc caggccatgc
     4021 taatggaact gcaatcttaa aaaatacttt ccattcatta agacctaatg ttctagcagc
     4081 tgacaacata ttattatcaa tctgttcaaa agctgacctt gaagttctat acatcatagg
     4141 aaaagacacc actactgctg aaattacagt tgctgtccaa ctaaatatta aagtcctatc
     4201 gaaatttaat aaaaactttc ctataaatcc attcttccca catagtaata ataaaaagaa
     4261 acctacaact gttggtggca aaattagtgg aagtgtaaat agtccatcta taagaccctt
     4321 ccacttacct ctatagttag ccataatata tgacacaaat attcctatta caaaagttat
     4381 tattgttgac aaaatagatg tcttaagtga tatccataag ggtgaccaat ctgttcccat
     4441 ctttccctcc ttaattttaa atggaaatag tgaaactaat aactctatta atttcactat
     4501 ttccatttta ttataataca caattatttt caattttcat ttatttatat ataatttata
     4561 cttaattaca cataatttat ttctaagttt attctacttt tttatatcca aattcttcaa
     4621 aaatcttttg tcctgactca cttaataaaa attcttcaaa tttcttagca gcatctacgt
     4681 ttttactagc tttaattact gaaactggat atgtaatagg cgaatgagtt ttttcgtctg
     4741 ttttttcaac tacttttatc ttatcattat tgacagtatc actgaagtaa acgaatccaa
     4801 catcagcatt tcctgattgc acccatgcta aaacttcttt tacatctttt gcaaatacta
     4861 gcttatcttt taacttatct tttaaattta aattagttaa cacctcatct gcatacttac
     4921 cagctggaac actttcagct tcaccaacag caattttctt cactttatct gtagtcaaat
     4981 ctttcatacc tgatacacta ctgtcagcag aagaaataag aactaaatca ttttttacta
     5041 aatctttcat agtatcagaa actaataact tctcttcatc caaagctttc atttgttttt
     5101 gacctgctga aataaataaa tcacaaggtg ctccttgttc tatttgttgt tgtaatgagc
     5161 ctgatgctcc atagttaact gtaagtttta catttgaatc aactttttta tattcttctt
     5221 caatctttgc cattgcttct tttaaacttg cagcagccga tatatttaac tctactgaat
     5281 cactactttt agttgttttt tcttgttttc catcatcttt tttgtcttca ttactattgc
     5341 acccaactgt ccccaaagtt aaacatgcaa ctaatcctaa tattcccaat atttttttca
     5401 taacaatctc cctttttgta aatttgatac acattttaac atgttttatt atgttttatc
     5461 atgttttgtt atatatagtt taattatata tacatgataa taaattttca agtaatttat
     5521 ttacactact tttaaatatt ttgctacatt ttcctttttt taatgttaaa ataaccttat
     5581 atggaggtgg attatggact cattatcatc tttgacacct gtcgaggtag ctgaattatt
     5641 aaagataaca aaaaatactg tatatgaatt aatcaaaaga ggtgaacttc cttcttataa
     5701 agtagggaaa aaaataagag ttgatactaa agatgttgaa gaatatatca acagccaaaa
     5761 aactggtaaa gtaaaggata cacatttcaa caataaaaat atagatataa ataataattt
     5821 caaaattatt atttctggtc aagatgtaat attagacatt ttagctaggt ctgttgaaaa
     5881 aaaattggat ggaataagta catttcgctc ttatataggt agttataatg ctttgtatga
     5941 gttatataat ggcagagttt ctatagcatc atcccatcta tgggatttcg aaacggatga
     6001 atataatagc acttttgtta aaaagctatt gccaggaata ccatgtgtac ttataaatct
     6061 agcttataga atgcaaggtt tctatgttgc taaaggaaat cctaaagaga taacaacctg
     6121 ggaggattta acaaaaccaa gtataaccat tgtaaatagg gaaaaaggtt ctggaactag
     6181 ggttttacta gatggtaaac ttagacttct aaactttaat ggtaaacata taaaaggtta
     6241 tgataatgaa gaattatcac atcttggagt tgcaagtact gtttctcgtg gaatagcaga
     6301 tgttggtttg ggaaatgaaa aagctgcttt acaagtaaat aatatcgact ttattcctct
     6361 tcacaaagag cgctatgatt tagttattaa aaaagaagac ttacaaaatc cagtttacca
     6421 aactataatt aacataataa actctcctga gtttaaagct gaacttcaag gtcttggcgg
     6481 atatgattta actgatactg gaaaaactat agcaaaagtt taagattaaa atcgcaatct
     6541 attttataag atttataatt tttcacaaaa tttataactt aaacacgaaa taaattgcga
     6601 ttttagtgtc tcaaaaaatt tatgtctttc attttatcat ccaatacaaa atataatata
     6661 attaattgtg caatcatatt atattaatat atatttacat aatagtattt ttctttaatg
     6721 tagattaaca tatgatatgt tttaaacatc aatccccttg ctttcttata tatatgtggc
     6781 aacacatatg agtttaataa attatataca atgttgcttt cttcttgtat tttttcaacc
     6841 aacaagttat ttataaaatt acctttctca ttttcaataa tctcactcca atttatctta
     6901 acttttaata tatatcttcc cactaggtat acacactcta caataaataa taaaaataca
     6961 atgcagtcag tacctgttgt cttatataaa ttacccgata ctaatggctt tgcgaagaaa
     7021 ttataaaaat tcaaagtatc acccgtataa tcaaaaagta ttaatagcac tcctagaact
     7081 ctcaatactt taatattcaa catgttttta tctttattat ttttgttttt catatatact
     7141 acctctcttt tctttagatt tgattgtaat ctaatactaa ctcttttatt tgaggtataa
     7201 atgaatttaa ttggtagtta ttttcatttt tactagaaat taattcacat tactaaacaa
     7261 aacttatatt taaacataaa aatagcctat ctatctttta ataaatacaa aaataaataa
     7321 gctactaata ttcaattaac ttttatcact taaaacatta ctatctataa atttaaatat
     7381 tttattgaag tatactgtac tatcatgttc aaatccatca acatgaccaa taccttctat
     7441 aagccatagg tcttttttat catgtttaac taaatcatac attttcttgc tattttgata
     7501 attacaaaca gtatcttttg ttccatgtat aaacagtatg ggtacattag atttctcaac
     7561 tgactcatat ggttttacat cactgtacca aaatccagat ttaaacttat tatataaatc
     7621 tccacaagtc accacataat tgattaatat atctggtatt cgtttttcta gtactcccat
     7681 tctaattgca tctttcattt cagaataagg agaatccagt atataaaaat cgaccttatc
     7741 atcttttgaa tttatctctg aatgcatagc agctgtccct gcccccatgg aaaatccatg
     7801 cactcctaat cttccttcag gaaatttatt ttttacaaat ttaactagac tatctaaatc
     7861 atacctttca taaagaccaa atgtgtaatt atctccacca ctattaccag tatttctttg
     7921 attataaact aatacattat aacctttatc taaatatcta tatgctacct ttaacatttc
     7981 atagtaacta cttccaattc catgaacaag tatcatagta tctcttgtct ttatatttga
     8041 agttataaaa agactttcaa gcttgtaatt attagaactt tgtatcatta attcagatgt
     8101 cttgtagttt tttaatttct ccagtggttt atcttttctc tcagaaaata tttttactat
     8161 atcttcgttt tttattaact gctctaaacc aactgaacta ttatacacta atttgccaaa
     8221 tatataagat acaattaata ggattaatag aaacacaatt gatataatta taaatttatt
     8281 tcttaaacta atacaatttt taaaactatt tttcatattt atttaccata caattttcct
     8341 atattatatt ttctaagtaa tagcataatt gattatacta ttcttataat ttctattata
     8401 cctacttatt tattaaaaat acaaattata ttttattaat ttttactact tgtaaattat
     8461 tatcttatac aatgaatttg tattatataa taagtatttt taggattctg ttacataata
     8521 ttatttaaat attcttctat atttctcttc ttcttcttca gtaaacacat taaatacaac
     8581 ttttaaattt ttttcaggat tttcttttag ccatagtcta actctactta cagcaagatt
     8641 agctgcctct ttttttggat aaccaaatac acctgtagaa attccacaaa aaacaatatt
     8701 ttttatttca tcaatttctt ttattgtatt taaacatgat ttataacaat gaagcagttg
     8761 cttttcttgc tctttacttg gctgaccacc agatacaata ggtccaacag tatgtactac
     8821 aaattttgca ggtaaacaat aacctctagt tatcttagca tctccagtat attctaaatg
     8881 cccttgtttt tttattattt tgtcacaatc ttctctaagt ctaggacctg cgcatgaatg
     8941 tatctcatta tccacgcata gatgtaatgg ttgtaaacac cctaataact tgttatttgc
     9001 agcatttact attgcatctg ctcttaaatt cgttatatta cctctccata tggcaatccc
     9061 ttcctctact tcttctatat catttacatc tactaactct ctttcttcac attcaatcaa
     9121 caataaatta tgtaacatat taagtatctc tggagcaatt tcttttggtg gatatacatt
     9181 caaaagtcct ctaagtatat ctctaggctt aatttcatca tttgataaat tgtatatttt
     9241 agaaggaact tcttttgaaa aatatgcaat taaagtgttt atattttttc ttctttgttc
     9301 gtcagttaga ggcttgatag ttttatcaaa atcctcaaat aaatttacat catcagcata
     9361 atctctccac ttcatagcca tctctccatt cttgtatttt agacttaaaa ataattatgt
     9421 atttatgtac atatttattt atttctataa acacctacat aaatcctgtt aaaagtgtaa
     9481 attttttatt atgcaacttc tctggttatt tctattgatt gatagtaaat tattgtacct
     9541 aaatttaatc caactaacaa gtaactaaac ctactttcct aactgcaaaa tacactatgt
     9601 ttgccacttg tatctcattt gtaaataaat aaagtcccta caaatacatt aactaggcta
     9661 tgtactaaac tgtaggaact ttaaaaatat attattctta attaagtttt ggccaataat
     9721 ttttatttgc ttctattaaa tcatctagta attcttttgc aactgttgca ctaggaactg
     9781 tcttagatag cataagtgct tgccacaatt tattataaga cttctcaatc caagcatcaa
     9841 ctactaattt ttcaactgct aattgttgtt ctattaaacc tttttggaat gttggtattt
     9901 tccctattga taatggttca tacccgtctt ttccaactat acatggaatt tcaaccatag
     9961 catcatcttg tatattttct atagctccat tattttgaac tatcaataac atacgttcct
    10021 gtgtattaaa agctagagct gtagctaaat ccactataaa ctctgcatgt attcctatct
    10081 taagcccact gcccttagaa tgtccttgct tttctatcaa tgcacatgaa ccaaaaactt
    10141 ctttttctct tccatcaata acttcattgg cacgagtata atttacatca gaatgattta
    10201 caacataatc tggaaataga tagtacttta agtaactact tggtattgta gttaaatctg
    10261 tttttactat ttctttagta aataaattag tttcaaacca actatctttc ttgtcatttt
    10321 tcattccttc ttcaccattt ataaaaccat attcttttat atgttctact aattttggta
    10381 aaagttcatt tcctttttta tctttaattg aagtatacca accaaagtga tttaatccaa
    10441 agtatcttat atccatatgt ttacgagatt tgagtcctgc aatccttgct atattatgtt
    10501 ccatacctat tggcatatca caaatattta ttaccctaga attaggtctc aaccttctaa
    10561 cagcttccgc tattattgat gctggattag aataatttaa catccaacaa tttggagaat
    10621 acttttccat ataatctatg ttttcaagaa caccttctat agacctcatt ccataagcta
    10681 ttccacctgg tccacaagtt tcttgaccaa ctaccccatg ttttagaggt atcttttcat
    10741 ctagttctct catttcaagt tttccaactc ttatatgagc taaacaaaaa tctacatctg
    10801 tataagcctc tttagggcat gttgttgcta aatactctat attagggtcc ttttccttta
    10861 ttagtatttc acaagcttta gctaccttat tttgtctttc ttcatcatta tcatataatt
    10921 tgattgctct taatggtaac ctatctaagt tatctagcaa cattaatatg atttctgggg
    10981 tatatgtact tcctcctcca gctattacta ctgaaaattt ttccataata atatctcctt
    11041 ttctatttaa aaatttactg tatttataaa tatatttata aatactagta ctttaaagta
    11101 aaagggagtt catttattaa atctattaat ttaataaact atagccaaac ttcaagcact
    11161 atttacaaga aatttaattc ttattaattc ttgggtccat catctcaaat atatctacaa
    11221 gttcagatac taaagaatga gcaaataatg catttgaata atggtcttca gagtgcacaa
    11281 ctaaaaaatc agtcccacta tcttcactat tcatagcatt tgatagtaat tctaaatgat
    11341 actttgatgc tgtttgtatt ttctctgagg ctgaatttaa aaggtgtttt gctttattgt
    11401 agtcaccttt ttttatttcc ttaagagaca tcattacatc acttttagca tctcctgctt
    11461 ctgatattat actaaatact ttttcttcca tttcaggtac catatccttc tccttctaat
    11521 gacttgttaa aaatcaaagc tatcatcatc taatgttgta gctaattctg catttttatt
    11581 taattcttcc ttctccatta tcttaaagaa tggataatat atcaaggtca taagtattat
    11641 acttgcaaat actaatacga ttgccttcca atctaatgtc atcaaaaatg ctgcaacccc
    11701 tggaggtaaa aaacctggtg gttctgcaat aggtaatcct actaatccta cttttaatgc
    11761 cataaaatta agtgctccaa ccaatacagg tccaaataca aatggtacaa acatatatgg
    11821 gttcataact attggtgttc caaatattac tggctcattt attccaaata gtgatggtaa
    11881 aatcacaact tttcccatac tattaaaact tttacactta cttcttgaca taaggtacac
    11941 taatcccaaa gttatccctg aaccagttac ttgcaagaaa ccatagtaaa atcctattgt
    12001 aaacacatat tttgggtctc ctcctgctgc tatcagtgtt gcattttctg ccatatatgt
    12061 agctgctatt ggcatccata tacttgaagt tattgctgct ccatgaagcc caaagaacca
    12121 taataattga gttataaata gtattatagt tactgcaaaa acattatcta cactgcttat
    12181 agctggtgct aagaaattca ttataatagc tggtagtggt tgacctgaga catttttagt
    12241 tattgctgct attgctgtaa ataacattat acatactatc attggagtta agtttctaaa
    12301 acttttattt actacactag gtacttcttt tggaaatcta attacgagat ttttatcatt
    12361 cataaactta gtaatatcaa ctactaaaag tgctactaat atacttacaa ataaaccttg
    12421 tgcatctaaa taacttgtat ctaatacacc atctactact tgtccacata caacaagttg
    12481 tgcaacaact gctgtcatac ctatttctac atgattaaga ttatattttt tagctagtgc
    12541 ctgagctata aaaaatgctg aatatataga taataaactc atagtaaatt tattagggat
    12601 aagtaatgta tccatatttt cagataataa tgtttttgca cttccttcag gtaacatatt
    12661 gtttaatgcc ataaataaca tacttaaaga accaacaatt attattgggg taatacttat
    12721 cataccttct tttatagctt gaagatgcct ttgtttttca atcttttgtg ctattggaag
    12781 aagaaatctt cttaaattat tttgaagtgc ttccattttt attcccccca attatctatt
    12841 tttatataat tcgattgccg acttcataac agaaggagca tccatacgac cataatgctt
    12901 agtatctatt aaaccaactg ctattttgta attcttacaa gcttcaacta catcatcttc
    12961 cttaaaccta atttgtggtg ctacaagtac tacatctgta tcattagctt caatgtatga
    13021 ttttaaattt tcaaatgatg ttgcctctat atttatagtt ttagttttta acttttcatg
    13081 ctcactacaa aaacttttca tcttttccac aagtacacct gttgaagctc catttgcaca
    13141 tactaataaa atattcataa ttaccctcct acaatatcta acctcttttg ttttctaatt
    13201 ttttatcagc caattcttac tctaattcct atcagttttt actttaattc ttattatttt
    13261 attttaattc ttagtaatat ttactctaat tcttagtact gccaatgatt aaacttgaaa
    13321 gccgtatcta taacttcttc ttgcttatat ttttctaata tttttaagta tctttcttta
    13381 taatcattat ctacttcttt ttctggtatt actatactag cttcatttaa aaagtggaat
    13441 gaatcccttc ccatttctaa tcctctatat gtatgcttgt caagtgccac gtccataact
    13501 tctggaactt tacccattgc aaatcctttt ataattatat tttttaataa atcacttgat
    13561 ctatctttct cacatgcaca aagatatctt attgcatgta tgaaaaataa aggtctgtct
    13621 ccatctgcat atgaatattc ctttcttact tgatttaaat tatttatgat tattacagct
    13681 gatgggtccc ccattcctat atcttcaact gatattgtaa gtatccttct ccatagctta
    13741 tcttctaatt ctggtgatga tatatatagt tcataagcaa attcacaagc ttcttccacc
    13801 atatttcttc ttatagcttt ttgaaatgac gatattattt cgtctgcact aaatccgttt
    13861 cttgtagtca ttcttgccca tgggtcattt gcctttttat ctcttaatat tttatcttgc
    13921 atattattta ctccttttta tttaaatttt aattatttat attactcatt taataatata
    13981 agcaagtatt atgccagttt ttttagacac tttaaaacac tgttatttca atcattttta
    14041 tcatcaaaac ttagatactt tgtctaagta tatttatatg tgtctaatat taatattatt
    14101 ttagactaaa aaaaattacc aaataagttt ttatactcat tggtaatctt tttcgattat
    14161 ttctgcatat tctaatatta ataatatttg atagcactct ttttcattaa tttctatatt
    14221 atatttttta tctaattgag atactatatc ttttattttg cttaggctct tgtgataatc
    14281 aagtgttttt tctttatcaa gcttttcaat ttctctagta tttccaatca acccatctac
    14341 catgaaagct aaatgcatca taagtccaat tactttatcg tatttctttt ctatattaaa
    14401 tactaaaaac aattcatcag acacatattt tatatcttta aatatcctat tataattaga
    14461 gctttttaag gatgtcttta aaccttcaac tacatcatca taacctatac ttatctttat
    14521 aatatttttt aatttattga tattttcatc cttatctata tcttttttgc taatatagtc
    14581 aattcctcta atattaattc tttgttcatt gattactgca acaatattac tactttcttt
    14641 aagtttcgta atatttaaac ttaaatcttt ttctgtttta tatgggacag atataatatc
    14701 tattccatct aagtacctac tcatcttttc ttctaatatt tttcttgttt tattatctac
    14761 accttctgaa acatgtgatg ctataataat tgttttagac agattttctt tattttgaat
    14821 ttcattagtt ccaaaatagt actttctcgt gttagtgata gagttgtata cgtcatttaa
    14881 aggtaatccc atattggcct tctgaactgc ttctaacaca gttaatgtcg tcaccatagg
    14941 aattactctt actccacact ttttttcttt ctttataatt tcatcaaaag agtttaatga
    15001 acccatatct gtaaatagta atacatcttt attgtctata ttattaatta aatttttaaa
    15061 atctacaatt acttcatcat agcttttatc taacttcata tcgaaagaaa tagcactgca
    15121 ctttccaata atatcaccaa ctgcttttac catactactt gctgtagttt ctccatgcat
    15181 agcaactata atattaatgt tattcactat tttattttgt tcatcttgtt tagcttgtac
    15241 tatgaataat gtaatatatg ctacagtttc tatagataaa aataaatcaa attcattttc
    15301 aattattcca actattttta atgctgtttt aaattcactt ctgttatttc ttctaatttg
    15361 attcaaatct atgttgtttg tagagctact tttatccaat acacttttta tataaattgc
    15421 cattgactta aatattgatt cacttatatc tatttcttca tcttctttaa taatttgtct
    15481 tattgattca cacatgcttt taaacttaac attattaaat agagaagcat ctgctatatt
    15541 catttctaca gatttattaa gattagtatt tactgcatta ataatattta tatcattgta
    15601 gttaataact tcttcttctc ctaatgacgt aaatacaaaa tattctattc catgtgttat
    15661 aacttcatct gctttaatag acttctctct ataatcatca ctcacttcat ttatagattt
    15721 atcaaaatat tttttctcta tataaactgg ttctttatta tctcttttat atcttaggta
    15781 tccatttgca acagctaatt ttatatcatt ttgaagttga cctacattat ttttacaatc
    15841 ataaagtaat agtgatttaa ttatttcttt atgtactttt attgaaatag aaatactttt
    15901 tgattcttcc ttgaaaaaat ttttgactaa ttccattctt tcaatcattg tcctatctct
    15961 caatgatggt atttctattt tcattggtat tcttctattg aatgtatcta atagtgttga
    16021 tgtcggattt tctgtagtag cacatattat taatacctta gactctcttt ctttcgttgc
    16081 atctcctagt cttttaaatg ttcccttatc tataaaagta aacaacattt cttgaccttc
    16141 tgctggtagt ctatgaattt catctaaaaa tagtatccct ccatttgcaa tttccaaaag
    16201 accttttctg gaagattctg cacctgtata agctccttgt tctaccccaa aaatatgtcc
    16261 cataagtaat tgtgcattat tagcataatc agcacaatta aatgttacaa aaggagcttt
    16321 attttttcta attccactat ctatagaata atcgtacata tatctagcaa tcatactctt
    16381 tcctactcct gtttctccat agataatagt atgaagtcca tttgtaggat agagcattgc
    16441 gaccttgcat ttttctatta taggtcttaa actatgttct ttacctatta gtgtttcaaa
    16501 actatctttt tttattttgt tttctacttt tgttcctttt tttatgccaa gcaactcact
    16561 ttgtgtatca agcaattcat tcttgttaag gttaagattt gcagggatat aatacacagg
    16621 tcttcctttt atcttcgtaa ccataccctc attgaataat tggtttaaat atgtacttat
    16681 attgtttctt gcaattcctg tcttttctga taattggtta gctgtaatcc ctttttcatt
    16741 ttccctatat gatgattcta aaactttcat tactttatct tttttatata tcattacaag
    16801 ctcccctaca ttatagtatt ttattaacta aaacccctat acacacttta ttttttaata
    16861 aactcttatt ctttaactaa ggttataatt tatcaaactt tccttacttt aaattataga
    16921 aaattattgt agaaaaaata agattattgc tcattttttc tacattacta tttttaattt
    16981 tatagtactt tcttaacaac atactttact tgtttttaat tttattatat ttgaatttat
    17041 tatatttgaa aagtagaaat aaaaaaccct attttggagt agttttaaaa tttctccaaa
    17101 aatagggttt tagtttgtat ttcaaataaa tacctgttca agtattttta tactaaacaa
    17161 cttttaaatt ttgttggtat ttatttatgt ctgatttaga agaatataca aaatgtccat
    17221 ctgaaacctc aatccaactt aataactttt catttgaaca atcatatcca ttagaattat
    17281 actctattct atttcttgac ttagcatatc tagggtcagg aacaggaatt gcagaaagta
    17341 gtgattttgt atatggatga ataggattat tatacaattc atttgaatct gccaattcta
    17401 ctaattttcc attatacata actcctatac ggtcactaat atgtctcacc atagataaat
    17461 catgagctat aaataaacaa gttaaattct tttcttgttg caacttttta aataaattta
    17521 ctatttgtgc ttgtatagac acatccaaag aagctatagg ctcatcagct attataaatt
    17581 ctgggtctac tgaaagagct cgtgctatgc caatacgctg tctttgtcca cctgaaaaat
    17641 cagatggata cttatttgca taacttctat caagtcctac tagctttagc atctcatata
    17701 ctttattcat tctatctgtt ttatttttac agataccttg aatttttagt ggctctgaaa
    17761 ttatatctgc aattgtcata cgtggattta atgatgaagt agaatcttga aaaataatct
    17821 gcatactttt gtttacatct ttttttataa atttgtacgt ttttttatct gatatgcaat
    17881 ttcctttgta aattacttct ccaccagtag attcatgtag tcttattata gttttaccag
    17941 ttgtagattt tcctgaaccc gactctccta ccaatccaaa tatctcaccc ttatatatat
    18001 caaaacttat atcatcaact gcttttacag tagtactttt gtccaaatga aaatattgct
    18061 ttaagttttt tatttccagt attttttctc tattcattag aaatcaccct tccacaattt
    18121 actctaactg gtacatctac ttcaggtgca tctgggtgca ataaccaagt tgctgcacta
    18181 tgtgtatcat taattttaaa cattggtggc tctttttcat aatctatctt aagtgcattt
    18241 ttattcctta ttgcaaaagc atctcctttt ggtgggttca ataaatttgg aggcattcca
    18301 ggtatattat ataaatagtc atcctgcgaa tctaaagtag gtaatgaacc caacaacccc
    18361 caagtatatg gatgtctagg gtcataaaat atatcctcta cagttcctat ttctacaatc
    18421 tttcctgcat acataactgc tattctatca gctatagttg caactactcc taaatcatga
    18481 gttataaata ttattgacaa acctatttta tgttgtaaat cctttattaa atcaattatt
    18541 tgagcttgta tagttacatc taaagcagtt gtaggttcat cagcaatcaa tacatctgga
    18601 ttacaggcaa gtgctatagc tattactata cgttgtctca ttccacctga aaaatgatgt
    18661 ggaaattgtt taaatctttt ctcaggatta tcaattccaa ccaattcaat aagctctatg
    18721 gctctctttt ttgcttcact tttacttata ccttgatgaa tgattacagc ttctgcaatt
    18781 tgctttccta ttgatatagt tggattgaga gatgtcatag ggtcttgaaa tatcattgat
    18841 atattctttc ctcttatatc ttccatctct ttttcagact tcttaaccaa atcacttgat
    18901 ttaagtaaaa cctctccatt tttaatatat ccattgtatg ggagtatcct catcaaactc
    18961 ttacacagta cagatttccc acaaccagat tctccaacta tagccaatgt ctcacctttt
    19021 tttagattaa aagatacatt tcttacagcc tgaacttctc cttcttctac tttaaaactt
    19081 acagatagat tattaacctc caataaatgt tccaaaaacc atcaacccct atgctattca
    19141 aaccttaggg atatattttt atccctaagg tttctaatta atttcagtat tattcaattg
    19201 tccagtcagc tatgttccag aatataccta caccatgatg acctaaaact gtatcaggtg
    19261 ttaatccttt tatgtttggt tttccaacat atattgcatc tatataagca ataaatgtat
    19321 aaggcatatc cttagtcatt tctacttgga attgtttata taactttaat ttttcatctt
    19381 tatcttctgt ttctcttgct ttttgaagta ttttatctat agtaggatta gagtaagcac
    19441 tgtaatttgc acctttatct gttccaaata ctttatatgt atggtcatct gggtcaaatg
    19501 gacttcccca acctattaaa tgagcatctt gattagccca atctgtttca gttacaacaa
    19561 cagctttagc atcaacacca atttctttta actgttgtgc acatatttta gccatatcaa
    19621 ctctaacttg gtcactctca cctgctgtta tctcgaaagc taacttagta ccttcttttt
    19681 catagattcc atcagaacct aatttccaac ctagcttttc aatttcttgt ttagcttttt
    19741 ctggattata ttcaaacttt tctatatcag gattattata tggtcccatt tgtaaaggtg
    19801 aatatgctgg tacaccatgt cctaataata cactgtcaac tattgctttt ctatctattg
    19861 catagcttaa agcatttggt aatcctttag cttttttatc tttaaagaat ttagaattaa
    19921 aattgtataa tatacctcta tagtcggctg ttttcattat atttacttta aaattctttt
    19981 cgtctttttc aaagttagac atatctttag gagttatttg agctaggtct aattctcctg
    20041 attttaattg cattgcctta gccttatcat ctggaacaat cttaaagact actttatcta
    20101 atcctggttc ttttacaaaa taatcactat tcttaacaag tgttatactt tgacctttgt
    20161 cccatttttc aagtttaaat ggtccagtac ctattggttt ttgattaaat tcatcagtag
    20221 ctatatcctt accttccaaa gcatgttttg gtaatactcc tactgttaaa taatcaagca
    20281 ttgctgtatt tggagctttt aaagtaattt ttatagtatt atcattaacc acatcaattt
    20341 ttgttatatc ttcataattt gatgctatct cagaagcatt atctggattc attatagttt
    20401 ctattgtaaa cttaacatca tttgctgtaa atttctctcc atcatgccac ttaacatcat
    20461 ctcttaaatt aaaagtatat gtatttgttg cctcatcaaa tttccagtcc tttgctagac
    20521 aaggaaccac cttattattt tcatcatgag ctgttaatcc attaaatatt aacgaattta
    20581 tttctccatg ttcatatagt gcaggattta tacttgtata gtcattactt ccataaacaa
    20641 gtacctttcc atctttaggc gtatctgcct tcttatcttt gtctcctcca ctagaacaac
    20701 ctgccattag actaagtatc attactaaac ttaaaacttt taacttcttt aatttcatga
    20761 tgctccccct tttgcttttt ataaaatatt tttcaaagct ttgaccccat ttatttaaat
    20821 agatatttca aatacctcag tatttgctta tttagtactc aaatgctgat ttataaatta
    20881 ctagattttt tattattatt ctttcttata taattaccta tatttgttat acacaccaat
    20941 gttgtaacca aaaatatacc cggaatcagt ataatccacc atctatttga aagtaatgct
    21001 tcctctgaca aagataacat acttccccaa gaaacaattt ctattggtaa accaattcct
    21061 aaaaagctaa gtgtcgattc agtaccaata gctgcgccta tgtttgttac aaccatgaac
    21121 attattgatg ccacaaaatt tggaagtaaa tgttgcttta atacatagaa gaatcctcct
    21181 cccatgctct tagctgctag tatgtattcg ctatttctta tttgtctaac ttctgttctc
    21241 actatcttag atatattcat ccaacttgtt atccctatta ctatggacat agatactgga
    21301 tttgaatttc caagtatagc ttgtacaaat attataatta atattgaagg tatactaagt
    21361 atgatttctg taaacctcat cattgcatca tctacgagtt cagatgctga accacttata
    21421 ctaccataaa caattcctat aacagttgat attacagtgg aaaatagtcc tataaataaa
    21481 gatatttttc ctccatacca tatcatagaa tatatatctc tacccattga gtctgttcca
    21541 aataaaaaag ttttatttgg agctaaatta gaacttgcta aatccatgta tgttggttca
    21601 tgtgtcatta taaaagatga gaatacactt ccaatgacta tgattgataa aataataatt
    21661 gatatatatg gtaattcttt aattttttta gataaggttt tctttgtttc tatatgttca
    21721 tcttctgcta ctaaaatata attttctcct acaatttcaa aatcactata ttgtggcttc
    21781 attagtatca cctctatcat atttcattct agggtctatt ttattgttta taatttgagc
    21841 taacatattc ccaaatacta ctaaagcccc tgttattaag cataaaacta ataacatatt
    21901 ataatcatga tactttgcac tttcaaaaca aagtgttcct aacccaggat aagaaaaaac
    21961 tttttcaact acataagttc ctcctagtat atgaggtatc gaaatggcca ttatactaat
    22021 atatgatggc attatatttc tcaggcaatg cttaaaaaca atagttctat tatttaaacc
    22081 ttttgcttta cataaaagca cataatcttc tcttatttcc tctagtaatt tatttcttat
    22141 catatatgtg taataccata gatggcttaa tataagtact gtaagaggta agattagatg
    22201 tgatatccta cttaatatac tggactcttc tcccattgaa taagcaccac tacttggaag
    22261 tatacttaag tttatactaa atataagtat gagtactaag gcaacccaaa atgatggaat
    22321 acagttggtt attgttccta atttgcatat gattctatca atgagcttat cttcatgtaa
    22381 tgtacaaaat attcctaaca ataaggctag cacaaaggta agtatatatc ctgaaccacc
    22441 taatattata gtgtttatat agacatcatt tataacagaa gtaacatttt gtttatattt
    22501 aaatgaaatt ccaaattccc cttttgatgc atttgaaatc cattttatat attgactgta
    22561 tattggttca tccaaaccaa gttttttcat agcattttct ttttcttgtg tactcattct
    22621 ttctactcca tccccatagt aagagattaa tgggtctcct ggagcaagtc ttgccatgta
    22681 aaaaacaata aaagataata aaaacattac taaaataaac tgcaacaact ttttcaatat
    22741 atcctttaac aaaccccaac ccccctttgt tgcaataaaa aaaaccacat aaaagcaaac
    22801 gtaaagtaac gttaaaacct tcgtggttcc attatcatta aacaaaatta aattttctat
    22861 atttatctat gagttaattt tagcatcatt tattaactgt gtaaacaaac tttttaaaaa
    22921 ttgttaaaat ttcatcaaat tattttattt atacctaaaa taaaattttt atattctatt
    22981 cttcattatt ttctataaaa ttataaaatt ttaggttgac tatataagaa aagtatatta
    23041 tattagtttg tatgcaaacc atttaagagg tgattttatt gaaaagtaat tatgactgtt
    23101 ttagaatagc catgctctta aaagaacttt attctaaaac tatgtacaca gtagaagaaa
    23161 attttaaaga aaatggatta acacaccaac agattatagt tataaaactg atagctcata
    23221 atcaagaact tacaatatca caactatgtg atgaaatgtc tttagctaaa ggtacggttt
    23281 caggcataat cagcagatta gaacagattg gatatataga aaaattcaag aaatctaatg
    23341 ataaaagaaa tacatacgtt aagtttacaa caacaggatt tgaatttgcc acaaatttta
    23401 aaattaaaat gcaagaaagt tttgatgata tttttaaaaa ttgtgatgaa aacgaattga
    23461 gtgacttagt aaaaaatctt agaaatatat tggcaaaagt aaaggagaga taattatgaa
    23521 ttataaatta atacttgcaa tagtatttat aacatcagct ttaattttct acactatagg
    23581 tgtatttgga gaaagaaagg caaaaatttt aaaaaagaaa catgtaatta tattttggct
    23641 tggttttata tttgatactt taggaacatt tacaatgagt aacatagcca acagccatac
    23701 ttttgaagta aaatctgctt tatcacaaaa ccttcatagt attacaggtc ttcttgcaat
    23761 tgtacttatg ctttttcatg caagttgggc tacttttgtc ctatacaaag atgatgagga
    23821 aaagaaaaaa ttctttcata agtttagtat agttgtatgg actatatggt tagttccata
    23881 ttttataggt atgtttattg gtatggctgg atagtaaaat aaaaagtgtg taagaaatac
    23941 tgtaggtaaa tttgtataag acaaatttat ctacatcctt ctttcacact tttacatatt
    24001 tatttataat actccattat ttctttcatg tttcttaata cctatataga atatttaatt
    24061 atttctatag tattttatta ttttctcaca ctttttcata tatatattgt
//
LOCUS       DAMJXI010000056        22902 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.058, whole genome shotgun sequence.
ACCESSION   DAMJXI010000056 DAMJXI010000000
VERSION     DAMJXI010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22902
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.058"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            176..1012
                     /locus_tag="PC465_002773"
     CDS             176..1012
                     /locus_tag="PC465_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2650059.1"
                     /translation="MNIKKIFNNNVVVSSLEDGTEIIVTGAGVGFKKKVGDLIDENLI
                     SKKYFVQDDQRDKYNQILNKTSIEYFKISEEIIEKANEVLNTQVNDSIILALTSHIEF
                     AVQREKQGIKLPNLILNETKQLYREEFEFGLWAIDEIEKRIGIKLPEDEAGYIAIHII
                     NGLENSQKDEGINILEFSKQVIQIIEEVHGFKLDVNSLNYTRLITHLKFFVQRILRKE
                     TYNDSDIEDMYKLVNKNYNKPKVCTEEIAALVLDRFEYKISKEEELYLMIHINKITNS
                     GC"
     gene            1365..2942
                     /locus_tag="PC465_002774"
     CDS             1365..2942
                     /locus_tag="PC465_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2650060.1"
                     /translation="MKKNKLGLWNFFQMLGKTFMFPIALLSVSGMMLGLGAGFTDPKM
                     IEMVPFLGNEYVNLVLNFMLTIGLFAFNNLGALFAMAIPLGLLKKEKEFGAFSGLVGF
                     IAMHIGTNFYLTRADLLVPAEQMSTNGQAMIMGIQTYNTSVLGGIVAGLIVYAIYDKV
                     SNLKIPESLGFYSGPRLVPIVSLIVMSIVGLLIPIVWPPFFNAFQSLGRWISSAGPLG
                     YFSYAVAERVTIPFGLNHLVTSVFRFTPIGGTAVIDGETYFGTLNMFMAYVENNQIIP
                     LDLAGKMEQGKLMIQYGLAGAALAIYRTAKPENRKALKGLLISGVLTVIIGGISEPIE
                     FLFLFISPALFAFHTFMNGLANMVLPYLGVLMGFTGDLIAFISFGVLRGTATGWPIAV
                     LVAVLYFAIYYFVFKWAIIKFNIKTPGREDKEIKVSEGNGSDFKNLSTYKGQQMISAL
                     GGQSNILSLDNCVTRLRLKLQDVSLINEDAIKEAGGIAVVKLDEHTIQVIIGTQVYSL
                     RKQMDKAMEGHLEACND"
     gene            2935..4119
                     /locus_tag="PC465_002775"
     CDS             2935..4119
                     /locus_tag="PC465_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2650061.1"
                     /translation="MINFDKKVDRLGTYCTQWDYVEDRFGKKDLLPFTISDMDLEFPF
                     EITEVLQERLNHRVLGYSRWKHDDFRNSVTNWYIKRFNCSVDSNWIYYSPSVMYSISK
                     LIEMLSNEGDGILINTPAYNAFYDVITNNNRNIIKSHLVNRNGFYSIDFNDFEKKCKK
                     SKIFILCNPHNPIGRVWSELELVKMIGICKNNDVKIISDDIHMDIVYDNRMTPILNVA
                     KDYLDSVFICTSASKSFNIPALTGSYVIIPNEGIRNKFENITRYRDFVNSPAILAILA
                     TMVCYDDCEYWLDELLKYLKENLKYTIDYIKDNLEPLKLVMPEGCYFAWIDFSELKIS
                     GEKFQKLLMDIGEVAIMSGSVYGEEGEFYLRLNVACSREKLEDGLNRIKKTMDYIAKR
                     IL"
     gene            4137..4736
                     /locus_tag="PC465_002776"
     CDS             4137..4736
                     /locus_tag="PC465_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2650062.1"
                     /translation="MGYLKTMVDVMTTEMNAIRCLIDEAGIEYESIVSEIANCEGKVI
                     FMGVGKSAHIGKKLAATFASTGTPSFFVHATEAVHGDLGMIESKDITILISNSGNSME
                     VVNCIKYIKAIGSKTIAFTSNRNSVLAKECDYALIYPAKDEADHLNLAPTTSSTITLV
                     LGDSIACALSKSSNFGSSDFYKYHPGGSLGEKLKTANNG"
     gene            4760..5230
                     /locus_tag="PC465_002777"
     CDS             4760..5230
                     /locus_tag="PC465_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2650063.1"
                     /translation="MFKMFKKKSIKSPISGKVIELSKIQDGVFSQKIMGEGVAIDSTG
                     DIVYAPINGKIVVVAETKHAFVIELENGMELLIHVGLDTVNLKGEGFEVLVSMGEQVK
                     EGTPMLKINRPLIESKGISLITPVTITNHSEYNMNTCNVGNSVEGGKDTVIEFK"
     gene            5589..6335
                     /locus_tag="PC465_002778"
     CDS             5589..6335
                     /locus_tag="PC465_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HDF2650064.1"
                     /translation="MKIENLSIDDIKRGYIFNDDLNCYSCIKCTKTYEVGEIYKIGNR
                     FFEASKAIELHMELEHSDYLEQLLNSDSKYNTLTENQKQLFQLFISDLPDKEIAKQVG
                     VSTSTIRHQKFIFREKAKQAKFYLALYESVFEDKSNKSSTIIPIHEHARMVDERYVVT
                     EEERKHILDTSFESMNPLKLKVFSSKEKKKVVILSKILEQFERGKKYSEKEVNQILES
                     IYDDFATIRRYLIEYGFMSRNKECTKYWLT"
     gene            6396..7070
                     /locus_tag="PC465_002779"
     CDS             6396..7070
                     /locus_tag="PC465_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HDF2650065.1"
                     /translation="MNDELKSILYNKGVDIVRFVDISEFPINQTHGFSKAILFCIGLS
                     KKFITDIYNNLPTDSDEFLEKEEKVEELADWISKYIQNKGYRAYSQSEKNNLGHGYFE
                     KAYINPEMQSGISPLPHKTIANISGIGFMGKNNLFVTEEYGCAFSMCTVLTDAPISVE
                     RYPLIDSKCMDCNVCVENCPAKAIHGNEWTLPGKRESIIDVSKCFCVLRCMMSCPWSL
                     RYANQK"
     gene            7438..8784
                     /locus_tag="PC465_002780"
     CDS             7438..8784
                     /locus_tag="PC465_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HDF2650066.1"
                     /translation="MEIETKTPDWINVLELNSKIDITGKYDVSNMIQDIVSDKSLEGS
                     IIYFPKGNYLFEKGIKISQQITLQGDSYYGGDNQVSNLDKKQSIIGTTNFITRGVSNM
                     SIIALTGTSQCIKNINFYYDSHDIEKIPPKNVSAITEYGETQGLSHFEHLFISGFSGI
                     GIEIPYYSTGNDITVSSCGLGMRLGEKSMLSSSKIYECKNGMEITTGVSLNNVRIEEI
                     KEIGINNKGFGFNLIMNLMVDQCGYCGFMFEKMCYSQITARITRCGQYYKSVDYNAYE
                     NMEDRKEEAYSIFYGDILENCNIVLMNSNIDTLENDSLDEHKIYVIKANETNNVMLTC
                     YAEADNFIQCAKGNLLLENGVNTYKFYNGEICSVGGVQISDIDEKDLIKIIENTLYID
                     DKGKYLMVPRLKKNTVIYSVLDSTEEINKLHGGIWEQIDVKVLAGESMYYYKKIKD"
     gene            8811..10211
                     /locus_tag="PC465_002781"
     CDS             8811..10211
                     /locus_tag="PC465_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HDF2650067.1"
                     /translation="MEESIIIKDISGWINVLDYGICNDETKDVSFKLQEIMDAVPEDS
                     IIYFPKGKYLFESGVKIKKRLTLCGDSYILANVPKNTAGVTQFTFKGKKNPKSENIAI
                     ITAKSVRHCIKNICFYSDSCDRDMTSNHEPPTDGKPRFHHNVIINYRNISAVICEDKQ
                     GEPGHYENLSFSGFSGIALDMPNNSTANDITIFTSGLGISTGENSTIANSKVWGCVDG
                     MIISTGTFINGMRVEEIKKVGIKNIGRGLNFITNITIDQCGYCGVWFDSISNVQISGN
                     ITRCGQYYYDVSYDNYLMLDNRVKEAYSLFYGNLLESSNIVLSNTNEDNWEDFKEDKH
                     KVYLIEALKTKNVLLTCNIDATDWIVKSEKGNLTYNNMRQTVIFYDGKLSNINGIGIS
                     DEDYGDKVKIKKGNIYINSNDKDIKMHKPEVGDIMSTIIKDKSILSAHYGGTWEKIGE
                     KIEFGITVHYYKLIEK"
     gene            10421..11857
                     /locus_tag="PC465_002782"
     CDS             10421..11857
                     /locus_tag="PC465_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HDF2650068.1"
                     /translation="MEGRTGIKDGRWINVVERGIKNDGSYNVGPALQDIIDEIETDFC
                     VLYFPKGKYLFTSGVKINKEIVLQGDSNSSTGTTQFITRGVENMSIITLTGKKQCIKN
                     INFYSDSCEIQVNKEPPAKGNPKYHYEMIINKNEKNVEMNNVSAILYDNSKNMIKGLG
                     HYENIYISGFSGTGIRIPYYSIVNDITVSSCGLGIDTGIDTIISNSRISKCQNGMRIR
                     TGTSINNVRIEKIQKVGLISSQVKGYEGYGSYKINNITIDQCGYCGFSFDSMKDSYFS
                     GIIRRCGQYYYNTDYDTYLSIKDRVEEAYSLFYGNYFTECNIDLVSDNKDNWDDGLEY
                     KHKVYVFKTLQIPKLTLRCNIDAYDYIVKSVHGGGNLMLKNNFNNYIFIDSSSPEVIN
                     GINFNYQKNGNLLRLNNGKLSYKNGKEETAIFRPNYGLIVASTDSECEQIEATYGEKW
                     EKLGSEVIGKETVYYYKHHEPEKTNQIQ"
     gene            12201..13145
                     /locus_tag="PC465_002783"
     CDS             12201..13145
                     /locus_tag="PC465_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 domain-containing protein"
                     /protein_id="HDF2650069.1"
                     /translation="MIVSVSRRTDIPAFYSKWFFNRLEEGFVYVINPMNPKQVSKIEL
                     NPHTVDCFVFWTKDVTPMLYDLNKLRDYKYYFHYTITSYGKEVETCILDKRKVIDSFK
                     ELSRKIGKERVILRYDPIFLSEKYTVDYHIKAFASLCNQLDGFTEKCIISFIDLYKKT
                     KFNTKALHIKPIEITEIETLSKEISKIAHKHGIILEMCSEEYNLSKFGIGKSKCIDDR
                     LISKIIGCEVEVKKDSTQRDICGCVKSVDIGQYNTCRHYCLYCYANFNYAKVEENCRL
                     YKEDNKLLIDTLRDDAKISIRDMKTIKVDNNKQISIFD"
     gene            13314..14246
                     /locus_tag="PC465_002784"
     CDS             13314..14246
                     /locus_tag="PC465_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HDF2650070.1"
                     /translation="MNLLKKYPIPIASLILSIFTLGNLLQSYSESLRNVIGFIGFILY
                     AIYIVKIILLRKGVKEQLENPLISSTFPTITMATMIFATYIKPLSLELSIMIWSIGIV
                     GHLVLIVLFSKKFLVKFSIKTVFPSWYIVYVGIVAASVTAPAFNQLLIGKIAFWIGFV
                     SYIVLIPVILKRVWIIKEMPEPSLPSIAILAAPGSLLLSGYINSFSDKNNVVLYLLFI
                     LSIVFYIIVLGYLPKLLRLPFYPSFAAFTFPMAISAMGMKLMNGYLTKSGNFISWISY
                     ASKLEEIIATVIILYVLVLFIIYLSKSETTSKAK"
     gene            14351..14818
                     /locus_tag="PC465_002785"
     CDS             14351..14818
                     /locus_tag="PC465_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C_GCAxxG_C_C family protein"
                     /protein_id="HDF2650071.1"
                     /translation="MKTKEEYLKEVRNISEEYFRKGEFFCSEAVLQTINDALGQPLSP
                     EITKLASGFPIGLGKAQCLCGAISGGEMALGIVYGRVHGEAMNPKMFEHAKGLHDYIK
                     KEYGATCCRAITKKWDGDNFMSPERKEHCIKITGQVTEWVADKLIEDEKLNIK"
     gene            complement(15062..15916)
                     /locus_tag="PC465_002786"
     CDS             complement(15062..15916)
                     /locus_tag="PC465_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009912760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HDF2650072.1"
                     /translation="MLTIIIALLPVMGWGLMPIVANLKKSSPHEQLLGTSISAFIFST
                     IITLVIHPEITFFSFCISMISGIFWSLGQLMQFKAIQIASVSKVMPISNGSQLTFTTL
                     LAVILFNEWTSSKMLLIGSLSILCIILGILLTNYQTKKSTDKNMLKCVGVVLLSSLFL
                     SLYVVTNQIFLIEGYRIILPQSVGMLITSSIIVKYFSKEIVYRENVLFNLITGILWSI
                     ANLGMFITTNTLGVTISFSISQSCVIVATLGGIIFFKEKKNKKEWLAIFIGIILIMSG
                     VFMLSIIK"
     gene            16082..18046
                     /locus_tag="PC465_002787"
     CDS             16082..18046
                     /locus_tag="PC465_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2650073.1"
                     /translation="MLTDMIQNREIKIIKFLLKEGHTTVKAIADDLDVSEKTVSKSLK
                     EVEAVLKKIGLSLIRKPKIGVYIDGDLKKILPYLDNKGSQIPTTREERVIYIYSVLLK
                     SNDYITIQQLSDELYISRGTIERDLAEVEKLLKNEGISIYKKPSKGIKLNISERDKRQ
                     LTAKFIHKFWSRNWYIKQEQESFYQAFEKIQADVNGIFSEDDLSIIIDILRNFSRERK
                     FEFSDYEFQSLVIHLAIAVERIRKGEYIEESLYTGNIENNQMSNTNYLAKQLEEKFSI
                     LLPKSEIGYINLHLVASDQHRDTNELKNTSTNPCETSTNNISNLREIIKNTLYETAYD
                     KDLIDGLTSHVHSSINRLKYGLSIKNPYVNTIKQNFSLSFEQALDLKKVIEFIYDIRI
                     NDDECAYIALHFEAFRERMKELPQNIRVILVCSTGLGSSRLLSARIKKYFPMIKIEKV
                     LSVQELVSSKIDADLVISTIYLELETIPTIVVSPILNESDIRTLERNIQNVSSCTSKK
                     YKSFRNLIFEENILLNIEASNYEDAINHITDNLIKKGFAKEGIAKSAIERENLSYTSF
                     QSIATPHANPSYIKKSNISVATLKNPITWGNEKVEVIFFISLENDKNLELDEIYEVFY
                     DFIDNKKNINDILSATSTKEVYDLLVEESI"
     gene            18046..18507
                     /locus_tag="PC465_002788"
     CDS             18046..18507
                     /locus_tag="PC465_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2650074.1"
                     /translation="MKISDVLKKEQIVFNLDTNTKEETIKKLSSIFVENGIVDNEEEY
                     VKSVLEREEHSTTGIGNGIAIPHGKSNAVKKSSIIFAKTKHKIEWDALDEKPVDSIFL
                     LAISNIDKDSNHLVLLSKLATKLMDDDNVDALKLANSEQEIINIFSEEGEM"
     gene            18510..18830
                     /locus_tag="PC465_002789"
     CDS             18510..18830
                     /locus_tag="PC465_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDF2650075.1"
                     /translation="MKRKIIAVTACATGVAHTYMAAQALKKASKKMGHLIKVETQGAT
                     GIDNELTTKDAQIAEVVIFAVDTKVRNAERFEGKEILEVPVNAPIKDAEKVINDALKL
                     IDTK"
     gene            18846..19946
                     /locus_tag="PC465_002790"
     CDS             18846..19946
                     /locus_tag="PC465_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDF2650076.1"
                     /translation="MLKKIVSELKKHVLTGISYMIPLVIAGAMIMAISRVGGSFYNIP
                     DIWDAKYAESASSIVRLLHDLDGFGGTALGLMFPVIAAFIGFSIADKLAIVPGLVGGM
                     IAKDIGAGFLGALAVGLIAGYTCLFIKNHVKLPKSAASIVPIFIVPVFGTLITVVLIN
                     YVIGIPFATLNTGLENWLNGLSGTNQILMAAIIGAMMAVDLGGPVNKAALTTSLALLT
                     SGIYAPNTAAMVGIVIPPLGLGLATILAKQKYNKQLREAGKSSLIMGLIGVSEGAIPF
                     AVESPLKVIPSCVIGTAIASAMAVGLGSVNATPISGFYGWFTVENWPMYVLSIAVGTV
                     IVAGLVIVLRGNPVIEDDEFEDDDFDEAEWES"
     gene            20066..22666
                     /locus_tag="PC465_002791"
     CDS             20066..22666
                     /locus_tag="PC465_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HDF2650077.1"
                     /translation="MIKAHIVNHTHWDREWYFTSGDALVLSEQLFTDVIDELERNPDV
                     SFVLDGQLSILDDYVQLHKEKIEIIKKLIKEDRLHIGPWFTQTDAFFARGESILRNLM
                     IGIFESKKYGKYMKIGYLPDTFGFNAQMPILLKHVGLDNIFFWRGIHLGKQVQSPYFK
                     WKSLNGESYIYAVNMPHGYGTGMLLEPSLKYVNGRLDPAIDFIKSYTDVDEVLIPSGN
                     DQLNIIGDFKNKIKAINDIGKYSYITSSYQEFLKYIKSIESLESYRGEFREPVLARIH
                     KSIGSSRMDIKLACDKLENKLIKRIEPLLVIAKKSKIEISNQLLINTWKKLLEGQAHD
                     SLAGCVTDTVTDDILHRIREANEICDSIENTIVKKISEGLKLSKNDILVFNTEAKRFN
                     GYKEIQVVSDSKNIYFKDNLDATIIEETYVKPRENVLEETPAGNIFIEEPGYYILKVR
                     INIQLPALGYKVVSFELSDKEMVSLDKSNDTFISNDNYKIIYEDGSLNLQLKDGTYIS
                     NFLTLKDSGNAGDTYDFSPLKNDEDIKLSFDKVYTEKALGYEKMVVKGTTLLPLTLED
                     RKNKYLNGKLNVKVSIVLSKENPLMDVKLCVDNTIYNHRLRVHIKTDIKDNKNIASLP
                     FGYITRENGVLDNWEDIYSEMPIDLEPLESNITLTNQNRSCTVFTRGIKEYQHIEDEI
                     ALTLLATTDELGKPDLLYRPGRASGDTTKKGHIRIKTDKAQMLKELEFSFAIYMDSKS
                     FDELEIANLTHNYLRECVNYQLQDYNFFLYRIDNKIQKSIVNKTVSRELEIISLPENY
                     LISACYPSYYSKDKFIIRVENPSSNRMILDEQIFKNRNGKIVNAIEDVEEEQVYEIAP
                     FDVISILLDL"
BASE COUNT         8990 a         2354 c         4044 g         7514 t
ORIGIN      
        1 aaatatgata aaatatgaca aattaattga tgacaataaa aaatattttg ttattgtagt
       61 attatagggt aaattgcaaa atatatacga aagtaaaatt ttaaatattg acattaaatt
      121 aaatatacta tactatgtaa gtgtgatgag agaatttttt tagaggggat ttatagtgaa
      181 tataaaaaag atatttaata acaatgtagt agtaagctcc ctagaagatg gcacagaaat
      241 aattgtcact ggtgctggag taggatttaa gaaaaaagta ggcgatttga tagatgaaaa
      301 tttgatttct aagaaatatt ttgttcaaga cgatcaaagg gacaaataca atcaaatact
      361 taataagacc tctattgaat actttaaaat ttcagaagaa attatagaaa aggctaatga
      421 agttttaaat actcaagtga atgattcaat aatattagcc ttaactagtc acatagaatt
      481 tgctgtccaa agagaaaaac aaggtataaa attaccaaac ttaatattga atgagacaaa
      541 acaactttat agggaagaat ttgaatttgg attatgggca attgatgaaa ttgaaaaaag
      601 gataggaata aaattgcctg aagatgaagc aggatatatt gctattcaca taatcaatgg
      661 tttggaaaat tctcaaaaag atgaaggtat taatatacta gagttttcaa aacaagttat
      721 tcagataatt gaagaagtac atggatttaa attggatgta aattcattaa attatactag
      781 acttataact cacttaaagt tttttgttca aaggattctc cgaaaagaaa cttacaatga
      841 tagtgatatt gaagatatgt ataagttagt gaataaaaat tacaataaac ctaaagtgtg
      901 tactgaagaa attgcagcat tggtattaga cagatttgaa tataagatta gtaaagaaga
      961 agaattatat ttaatgattc acataaataa aataacaaac agtggttgtt aggattgtaa
     1021 ctgataaagc aggcaaaacc taagtcattg agcttaacta ttagattaag ttttttgatt
     1081 taggtttttt tattagatac aatcaaaata cagacagtga cttttaggat tgtaactggt
     1141 taagcaggca aaacctaaat cattgaattt aactattagg ttaagttttt tgatttaggt
     1201 ttttttatta gatacaatca aatacagaca gtgactttta ggattgtaac tggttgagca
     1261 ggcaaaacct aaatcattaa acttaattat taaattaagt tttttgattt aggtttttct
     1321 ataaatttga ttatgttttt agataaaaat aggaggggaa aattatgaaa aaaaataagt
     1381 taggtttatg gaacttcttc caaatgttag gaaaaacgtt tatgttccca atagcactac
     1441 ttagtgtttc tgggatgatg ctaggacttg gggcaggttt tacagaccct aagatgattg
     1501 aaatggttcc atttttaggg aatgaatatg ttaacttagt tttaaacttc atgttaacaa
     1561 taggattatt tgcatttaac aacttgggag cattatttgc aatggcaatt ccactaggat
     1621 tattaaaaaa agaaaaagag tttggtgctt tttcaggatt agtaggattt atagcaatgc
     1681 atataggtac aaatttttat ttaacaagag ctgatttgtt agtaccagca gaacagatgt
     1741 caactaatgg tcaagctatg attatgggta tacaaacata taatacaagt gttttaggtg
     1801 gtattgtagc aggattaatt gtttatgcaa tatatgataa agttagtaat ttaaagatac
     1861 cagaatcatt aggattctac agtggaccaa gattagttcc aattgttagt ttaatagtta
     1921 tgagtatagt tggattatta atacctattg tttggccacc atttttcaat gcattccaaa
     1981 gtttaggaag atggatttct tcagcaggac cattaggata tttttcatat gcagtggcag
     2041 aaagagttac aattccattt ggactaaatc atcttgtaac atccgtattc cgttttacac
     2101 caataggtgg aactgctgtt attgatggag aaacgtactt tggtacattg aacatgttta
     2161 tggcatatgt agaaaataat cagattatac ctcttgattt agctggtaaa atggaacaag
     2221 gtaaattgat gattcaatat ggattagctg gtgctgcatt ggctatctac cgtacagcaa
     2281 aaccagaaaa tagaaaggca cttaaaggac ttttaatatc aggggtgttg acagttatta
     2341 taggtggtat aagtgaacca atagagtttc tattcttatt catatcacca gcattatttg
     2401 ctttccatac atttatgaat ggtctagcaa acatggtact tccatactta ggcgtgttga
     2461 tgggattcac aggagattta attgcattta taagttttgg tgtgttaaga ggaacagcta
     2521 caggatggcc aatagcagta ttagtagcag ttttatattt tgcaatatac tattttgtat
     2581 ttaagtgggc aattattaag tttaatataa agaccccagg acgtgaggat aaagaaataa
     2641 aagtatctga aggaaatggt tcagatttca aaaatttgtc tacatataaa ggacaacaaa
     2701 tgatatctgc tttaggtggt caatctaata tattatcact agataattgt gtaactagat
     2761 tgcgtttaaa actacaagat gtatcattaa taaatgagga tgcaattaaa gaggctggtg
     2821 gtatagcagt tgttaaattg gatgagcata caatacaagt aattatagga actcaagtgt
     2881 attctttaag aaagcagatg gataaagcta tggaaggtca tttggaggca tgtaatgatt
     2941 aattttgata aaaaagtaga ccgattgggt acatattgta cccagtggga ctatgtagaa
     3001 gatagatttg gtaagaagga tttgcttcct tttacaattt cagatatgga tttagagttt
     3061 ccatttgaaa taacagaggt gttgcaggaa aggttaaatc atagagtttt gggatacagt
     3121 agatggaaac atgatgattt tagaaattca gttacgaatt ggtatattaa aagatttaat
     3181 tgtagcgttg atagtaactg gatatattat agtccaagtg taatgtattc aattagcaaa
     3241 cttattgaga tgttaagtaa tgaaggagat ggaatcctta taaatactcc tgcatacaat
     3301 gctttttatg atgtgataac aaataacaat cgtaatatta taaagtcaca tcttgtaaat
     3361 aggaatggat tctattcaat tgattttaat gattttgaga aaaagtgtaa aaaatctaag
     3421 atatttattt tatgtaatcc tcacaatcca attggtagag tatggagtga gttagaactt
     3481 gttaagatga taggaatttg taagaataat gatgtcaaga taatatcaga tgatatacac
     3541 atggatattg tatatgacaa tagaatgaca cctatcttaa atgttgcaaa ggactattta
     3601 gattctgtat tcatttgtac atcagcgtct aaatctttca atataccagc attgactggg
     3661 tcatatgtga ttataccaaa tgaaggtatt agaaataaat ttgaaaatat cactagatac
     3721 cgtgattttg taaattcgcc agcaattcta gcaatattag ctacaatggt ctgttatgat
     3781 gactgcgaat attggttaga tgaactatta aaatacctta aagagaatct taaatatacg
     3841 attgattata taaaagataa tttagaacca ttgaaattgg tcatgccaga aggctgttac
     3901 tttgcttgga tagatttttc cgaacttaaa ataagtggtg agaaattcca aaaattattg
     3961 atggatattg gagaagttgc tattatgtcg gggtctgtat atggtgaaga aggtgagttt
     4021 tatttaaggt taaatgtggc atgttcaaga gaaaaacttg aagatggttt aaataggatt
     4081 aaaaaaacta tggattatat tgcaaaaaga attttatagt aggaagggag atagttatgg
     4141 gatatttaaa aacaatggtt gatgttatga ctactgaaat gaatgccata agatgtttaa
     4201 tagatgaagc aggaatagaa tatgaaagta tagttagtga aattgcaaat tgtgaaggca
     4261 aagtaatttt tatgggtgta ggaaaatctg cacatatagg taagaaattg gcagctacat
     4321 ttgctagtac tggtacacct agcttttttg tacatgcaac agaggcagtg catggagatt
     4381 taggaatgat tgaaagtaag gatattacaa ttttaatatc aaatagtgga aattctatgg
     4441 aagtggtaaa ctgtataaaa tatattaaag caataggttc taagacaatt gcatttactt
     4501 caaacagaaa ttcagtactg gcaaaagagt gtgattatgc tttaatatat cctgcaaagg
     4561 atgaagcaga ccatttaaat ctagcaccaa caacatcatc tacaattact ttggttttag
     4621 gagattctat tgcatgtgca ttatctaaga gtagtaattt tggttcttca gatttttata
     4681 agtaccatcc aggaggaagt ttaggtgaga agttaaaaac agctaacaat ggataaaagc
     4741 aaaaaggaga gtagttttta tgttcaaaat gtttaaaaaa aaatcaataa aatcacccat
     4801 atcaggaaaa gtaatagagt tatctaaaat acaagatggt gtattttctc aaaaaattat
     4861 gggagagggt gtagctatag attctacagg agacattgta tatgctccaa tcaatggaaa
     4921 gatagtagta gtagcagaga ctaaacatgc atttgtaata gaattagaaa atgggatgga
     4981 acttcttatt catgttggtt tagatactgt aaatttaaaa ggcgaaggtt ttgaggtatt
     5041 ggtgagtatg ggagaacaag tgaaggaagg aacaccaatg ttgaaaatta accgtccttt
     5101 gattgaatca aagggtatat cacttattac tccagttaca ataactaatc attcagagta
     5161 caatatgaat acatgtaatg taggcaatag tgttgaaggt gggaaagata ctgtaattga
     5221 gtttaaataa agaactaaaa tacaaggtta atatttataa atacctataa acttatgttt
     5281 tataagattg attgtataga tttgttgtat aaaaaagaac tctttaatta taaattaagg
     5341 agttcttttt tattttgtaa atattgttta gatttatata gaaaaacact tagtaataaa
     5401 tagaataaat aagtatttat atagctaaaa atctaaatag ttttgtttaa atatattttt
     5461 atattttgta atttcaaatt aataaataat tagatttgat aaacaaaaaa taaaaatgtt
     5521 gattacatta ataaacttta atataatata tttatgaaaa atgtaaactg tgaaatggag
     5581 gtagtaacat gaaaattgaa aatctttcta ttgatgatat taaacgaggc tatatattta
     5641 atgatgattt aaattgttat agttgcatta aatgtacaaa aacatatgag gtaggagaaa
     5701 tatataaaat aggtaataga ttctttgaag cttcaaaagc tattgaactt catatggaat
     5761 tagaacatag tgattattta gagcaattgc ttaatagtga ttcaaagtac aacacattga
     5821 ctgaaaatca aaaacaatta tttcaattat ttattagtga tttaccagat aaggagatag
     5881 caaaacaggt tggagtatcc acatctacta tacgccatca aaaatttatt ttcagagaaa
     5941 aagcaaaaca ggctaagttc tatttagcac tatatgaatc tgtatttgaa gataaatcta
     6001 ataaaagtag tactataata ccaatccatg aacatgctcg aatggtagat gaaagatatg
     6061 tagtaactga agaagagaga aaacacattt tggatacatc atttgaaagt atgaatcctt
     6121 taaaattaaa agtattttct tcaaaagaaa agaaaaaggt cgtaatttta tctaagattt
     6181 tggaacaatt tgaacgtggg aagaaatatt cagaaaagga agttaatcag attttagaat
     6241 ctatatatga tgattttgca acaattagaa gatatctaat tgagtatggt tttatgagta
     6301 gaaataaaga atgtacaaag tattggttaa cataattaaa ataataaatt ttactaatgt
     6361 gtaatgttat ttttatctag ggggaggagt caaatatgaa tgatgaatta aaatctattt
     6421 tatacaataa aggtgtagac attgttcgct ttgttgatat atctgaattt ccaataaatc
     6481 aaacgcacgg tttttctaaa gcaattttat tttgtatagg gttatcaaaa aaatttatta
     6541 cagatatata caataactta cctacagata gtgatgagtt tttggaaaaa gaggagaaag
     6601 tagaagaatt agctgactgg atttcaaaat atattcaaaa taaaggatat agagcgtatt
     6661 ctcaatcgga gaaaaacaat ctaggacatg gatattttga aaaagcctat attaatccag
     6721 aaatgcaatc agggattagt cctttaccac ataagacaat agcaaatatt agtggcattg
     6781 gatttatggg aaaaaataat ttgtttgtaa cagaggaata tggatgtgct tttagcatgt
     6841 gtacagtact tacagatgct ccaatttctg ttgaaagata tcctttgatt gattcaaaat
     6901 gtatggattg caatgtttgt gtagagaact gtcctgcaaa agctatacat ggaaatgaat
     6961 ggactttacc tggaaaaaga gaatctatta ttgatgtttc aaagtgtttt tgcgtattga
     7021 ggtgtatgat gagttgccca tggtcattaa gatatgcaaa tcaaaaataa ttttactaga
     7081 gaaggtatta aattgaatat tataaaattt ttaaaatgta agattatata agatttttca
     7141 aaataaaaat ttgtatagaa cactcagaaa tgagtgtttt tttattggaa ttaaattata
     7201 ttgatacaaa gcttaactat tttaatcatt atataaactt tgtattaaaa aattaagaat
     7261 aacttgctaa tagtaaaaat ataatgagat tataattgat ttataatata actgtaatga
     7321 tgttgtaaaa tgaaaattgt catctcaaaa ttcccaaaaa gagtaaaagt cacttcggtt
     7381 atagtcaaaa aattttttca gtgaaaataa tttagattta aaagggagga attaatcatg
     7441 gaaattgaaa ctaaaactcc agattggatt aatgtactag aattaaacag taaaatagat
     7501 attactggga aatatgatgt aagtaatatg atacaagata ttgtctctga taagtcacta
     7561 gaaggttcca ttatatattt tccaaaaggt aattatttat ttgagaaagg tattaaaatt
     7621 agtcaacaaa taacacttca aggagattct tattatggag gagataatca agtatcaaat
     7681 ttagataaaa aacaatcaat cataggaaca accaatttta taactcgagg agtttctaat
     7741 atgagtatta ttgcattgac aggaacaagt caatgtatca aaaatattaa tttttattat
     7801 gatagtcatg atatagagaa aataccgcct aaaaatgtat ctgctattac agaatatgga
     7861 gaaacacaag gactatctca ttttgaacac ctgtttattt ctggattttc agggatagga
     7921 attgaaattc catactattc aactggtaat gatattactg ttagttcatg tggtcttggt
     7981 atgaggcttg gagagaagtc aatgctttct agtagcaaga tttacgaatg taaaaatgga
     8041 atggagatta ctactggtgt tagcttaaat aatgtgagaa tagaagaaat aaaagaaata
     8101 ggtattaata ataaaggatt tggttttaac ctgattatga atcttatggt agaccaatgt
     8161 ggatattgtg gatttatgtt tgaaaaaatg tgctatagcc agataactgc cagaattact
     8221 agatgcggtc agtattataa aagtgttgat tataatgctt atgagaatat ggaagatagg
     8281 aaagaagaag cttattccat tttttatgga gatattttag aaaattgcaa tattgtattg
     8341 atgaatagta atattgatac cttggaaaat gattcacttg atgaacataa gatatatgta
     8401 atcaaggcaa atgaaacaaa caatgtaatg ctaacatgtt atgctgaagc agataacttt
     8461 atacaatgtg caaaaggtaa cttgctgtta gaaaatggcg taaatactta taaattttat
     8521 aatggtgaga tttgttctgt aggaggtgtt caaatttctg atatagatga aaaagattta
     8581 atcaaaataa tcgagaacac tctgtatata gatgataaag gtaagtattt aatggttcct
     8641 agattaaaaa agaatactgt aatatattca gtactagatt ctacagaaga aataaataaa
     8701 ttacatggtg gaatatggga acagattgat gtaaaagtat tagctgggga atccatgtac
     8761 tattataaaa agataaaaga ttaaattatc aaactaggag gtagtgatta atggaagagt
     8821 ctataataat taaagatata agtggctgga ttaatgtact tgattatgga atttgtaatg
     8881 atgaaacaaa agatgtaagt tttaagttgc aagagattat ggatgctgta ccagaagatt
     8941 ctattatata ttttccaaaa ggaaaatact tatttgaaag tggtgtcaag attaagaaac
     9001 gattaacctt atgtggagat tcttatattt tagcgaatgt tcctaaaaat actgctggag
     9061 taacacagtt tacttttaaa ggaaagaaaa atcctaaaag tgaaaatata gcaatcataa
     9121 cagcaaaaag tgtaagacac tgtattaaga acatttgctt ttattcagat agttgtgata
     9181 gagatatgac atctaatcat gaacctccaa cagatggaaa acctagattt catcataatg
     9241 taattataaa ttatagaaat atatctgctg ttatatgtga agataaacag ggagaaccag
     9301 gtcattatga aaatctatct tttagtggtt tttctggaat tgcacttgat atgcctaata
     9361 attctacagc aaatgatatt acaattttta catccggact tggaattagt acaggggaaa
     9421 attcaacaat tgctaacagt aaggtttggg gctgtgttga tggaatgata atttctactg
     9481 gaacttttat aaatggtatg agggtagaag aaataaaaaa agttggaatt aaaaatattg
     9541 gtagaggttt aaattttatt acaaatatca caattgacca atgtggatat tgtggagttt
     9601 ggtttgattc tatatccaat gttcagatat caggaaatat cacaaggtgt gggcagtact
     9661 attatgatgt aagctatgat aattatttaa tgttggataa tagagttaaa gaagcatatt
     9721 ctttattcta tggtaattta ttggaatcaa gtaatatagt tttatcaaat accaatgaag
     9781 acaattggga agatttcaaa gaggataagc ataaggtgta tcttatagaa gcacttaaaa
     9841 ccaagaatgt actattaaca tgtaatatag atgctactga ctggattgtt aagtcagaaa
     9901 aaggaaattt aacgtacaat aatatgcgac aaactgttat attttacgat ggaaaactaa
     9961 gtaatatcaa tggaattggt atatctgatg aagattatgg ggataaagtc aagataaaaa
    10021 aaggaaatat atatataaat agtaatgata aggatattaa gatgcataaa ccagaggtag
    10081 gtgacattat gtcaacaatt attaaagata aaagtattct ttctgctcat tatgggggaa
    10141 catgggagaa aattggtgaa aaaatagagt ttggaataac tgtacactat tataaattga
    10201 tagagaaata agtaaatacg tagtatttga atagatgtat tttattggag ggctaggact
    10261 atagttttaa tgtaaatggt ttggtaatag catggattga ataatataaa aataatataa
    10321 aaaattaatt tgattatgta aatttctatg aagtagtaaa actgtgactt tagtcatagg
    10381 aggttcaaac taagtaaaag ggaaaggaat atataatatt atggaaggaa gaactgggat
    10441 taaagatgga agatggatta atgtagtaga aagaggtatt aaaaatgatg gttcgtacaa
    10501 cgtaggtcct gctttgcagg atattattga tgaaatagaa acagattttt gtgtcttata
    10561 ttttccaaaa ggtaaatacc tatttacaag tggtgttaaa attaataaag aaattgtatt
    10621 gcaaggtgat tctaattcat ctacaggtac tacacaattt ataactcgtg gagtagaaaa
    10681 tatgagtatt attacattga cagggaagaa acaatgtatt aaaaatataa atttctattc
    10741 tgatagttgt gagatacaag taaataaaga accaccggca aaaggtaatc ctaaatatca
    10801 ttatgagatg attatcaata agaatgaaaa gaatgttgag atgaataatg tatcagcaat
    10861 cctgtatgat aacagtaaga atatgattaa aggtctaggt cattatgaaa atatttatat
    10921 aagtggtttt tcgggtacag gaattaggat accatattac tcaattgtaa atgatattac
    10981 agtttcatct tgtgggctgg gtattgatac aggaatagac acaattattt ctaatagtag
    11041 aatatctaag tgtcaaaatg gaatgaggat taggactgga actagcataa ataatgtaag
    11101 aattgaaaaa atacagaaag ttggtcttat aagtagtcaa gttaaggggt atgaggggta
    11161 tggaagttat aaaattaata atattacgat tgaccaatgt gggtattgtg gcttttcatt
    11221 tgattcaatg aaagatagtt atttttctgg tattataaga aggtgtggtc agtattatta
    11281 taatacagat tatgacacat atttaagtat taaagataga gtagaagaag catattcttt
    11341 attttatgga aattatttta cagaatgtaa tattgattta gttagtgata ataaggataa
    11401 ctgggatgat ggcttagaat ataaacataa agtttatgta tttaaaaccc ttcaaatacc
    11461 aaaattaaca ttgagatgca atatagatgc ctatgattat atcgttaaat cggtacatgg
    11521 aggaggtaat ttaatgttaa aaaataactt taacaattat atatttattg attcatctag
    11581 tccagaagtt attaatggaa ttaattttaa ttatcaaaag aatggaaacc tgttaaggtt
    11641 aaataatggt aaattaagtt ataaaaatgg aaaggaagaa acagctatat tcagacctaa
    11701 ttatggtctt attgtagcat caacagattc agaatgtgaa caaatagagg ctacctatgg
    11761 agaaaaatgg gagaagcttg gttctgaagt aattggaaaa gaaacggtat attattataa
    11821 acatcatgaa ccagaaaaaa caaaccaaat acaataaaat ttgtattata taatgatata
    11881 aagttttaat atatagtgtt tacctttaat gtaatattga tatatttgta tagtattaaa
    11941 tttgttaaaa agtaaaattg tagggtgctt gaaaatagca ccttttttag tttcattata
    12001 aaattagttt tgaaagttta ggaataatgt atatttattt ttaaagaatt ataactttat
    12061 taaggatatt ttaaatgcta gaaatgaatc agtaaatcat actggaatta tcttaaatgt
    12121 tttgattaaa ttaagtattt agagctataa ttatattaaa aatatattag aacataatta
    12181 tattactatg gaggttaaat atgatagtaa gtgtgagtag aagaactgat atacctgctt
    12241 tctatagtaa gtggtttttt aacagacttg aagaaggttt tgtttatgta attaatccaa
    12301 tgaatccaaa acaggttagt aagatagagt taaatccaca tactgttgat tgttttgtat
    12361 tttggacaaa ggatgtaact ccaatgttat atgatttaaa taaattaaga gactataaat
    12421 attattttca ctatactata acatcatatg gaaaagaagt agagacatgt attttagata
    12481 aaagaaaggt aatagattca tttaaggaat tgtctagaaa aataggcaaa gaaagagtaa
    12541 ttttaagata cgacccgatt ttcttaagtg aaaagtacac agtagattat catatcaaag
    12601 catttgcgag tttatgtaat cagcttgatg gatttacaga aaaatgtata ataagtttta
    12661 tcgatttgta taagaaaaca aaatttaata ctaaagcatt acatataaag ccaatagaaa
    12721 ttacagaaat agaaacatta tcaaaagaga tttctaagat tgctcataag catgggataa
    12781 tacttgaaat gtgttctgaa gaatataatt taagtaaatt tgggattgga aaaagtaagt
    12841 gtattgatga tagattaata tcaaaaatta taggatgtga agtagaggta aaaaaagata
    12901 gtacacaaag agatatttgt ggatgtgtta aaagtgtcga tataggacaa tacaatactt
    12961 gcagacatta ttgtctgtat tgttatgcta actttaatta tgcaaaagta gaagaaaact
    13021 gtaggcttta taaggaagat aataaattac tcatagatac tttaagagat gatgcaaaaa
    13081 taagcattag agatatgaag actattaaag tagataataa taaacaaatt agtatatttg
    13141 attaaaataa atatactaat taccttaata tattaagaat atagatactt ttgataataa
    13201 aattaaactt aatagatatt ttctatataa gaaagatggt cataatatgt caatttgacc
    13261 atctttttga tataattaaa acacaaataa tttagtaaca aaggaggcag aacttgaatt
    13321 tattaaaaaa atatcctata cctattgcaa gtttgatttt atcaattttt actttaggta
    13381 acttattaca atcttatagt gaatcattac gtaatgtaat tggatttata ggatttattt
    13441 tgtatgcaat ttatatagtc aaaataatat tacttagaaa gggtgttaaa gagcaattag
    13501 agaacccttt aatatcaagt acatttccaa ctataacaat ggcaacaatg atatttgcta
    13561 catatataaa accattatct ttagaattaa gtattatgat ttggagcata ggaattgtgg
    13621 gtcatcttgt gttaatagtc ttatttagta agaagttctt agttaaattc tcaataaaaa
    13681 cggtatttcc atcttggtat atagtatatg ttgggatagt tgcagctagt gttacggcac
    13741 cagcatttaa tcaacttttg attggcaaaa ttgctttttg gataggattt gtatcttata
    13801 tagttcttat accagtaatt ttaaagagag tatggataat caaggaaatg cctgaaccat
    13861 ctttaccaag tatagctata ttagctgcac cagggtcact attattgtct ggatatatta
    13921 attctttttc agataaaaat aatgtagtat tatacttgtt attcatatta tcaattgtat
    13981 tttatattat agttttggga tatttaccaa aattattaag attgcctttt tatccgagtt
    14041 ttgctgcatt tacattccct atggcaataa gtgcaatggg tatgaaacta atgaatggtt
    14101 atttaactaa atcaggtaat tttataagtt ggatttcata tgcttctaag ttagaagaga
    14161 taattgctac agtgattatt ttatatgttt tagttttgtt tattatatat cttagtaaat
    14221 ctgaaactac atctaaagct aaataagaat tattaaatat gtgtatttaa taggaatatt
    14281 gatataaata tatgaagata agataaacca tagaaactta atttagctta attttattgg
    14341 aggaaaacaa atgaaaacaa aagaagaata tttaaaagaa gttagaaaca tatcagaaga
    14401 atactttaga aaaggagagt ttttttgctc tgaagcagtt ctccagacaa taaatgatgc
    14461 tttaggccaa cctttaagtc cagagataac taagttagca tcaggatttc cgataggact
    14521 tggaaaggca caatgtcttt gtggagcaat atctggggga gagatggctt taggtatagt
    14581 atatggaaga gttcatggtg aagctatgaa tccaaagatg tttgagcatg ctaaaggttt
    14641 gcatgattat attaaaaaag agtatggtgc aacatgttgt agagctatta caaagaaatg
    14701 ggatggtgat aactttatgt ctcctgaaag aaaagagcac tgtattaaaa taacaggtca
    14761 agttacagag tgggttgcag ataagcttat agaagatgaa aaacttaata tcaaatagtg
    14821 taatattagt tggtgaattt ataaagttaa atttacttat agtataagat acttgatatt
    14881 ctcgtattga tagaaaaatt tatagcatat gtatttaatg aaatatactt atatttagag
    14941 tgtggtttaa tttcataaat acatatgcta ttattttaag tatataagca aatttattta
    15001 aataaataga aacagttaat ttatatgtac aaaactatat atgattagtg taaataaata
    15061 cctattttat aatactcaac ataaagacac cagacatgat tagtattata ccaataaaaa
    15121 tagcaagcca ttcttttttg ttcttctttt ctttaaaaaa tataatccct cctaaagtgg
    15181 ctactatcac acaactctga gagatagaaa aacttattgt aactcccaat gtattagtcg
    15241 ttatgaacat acctaaattt gctattgacc acaatatacc agtaattaaa ttgaataaaa
    15301 cattttccct atatacaatc tctttagaaa aatacttgac aataatagat gaagttatca
    15361 acataccaac agattgaggt aatataattc tgtatccttc aattaaaaat atttgattag
    15421 ttacaacata taatgataaa aatagagatg ataataatac aactccaaca cattttaaca
    15481 tatttttatc tgtagatttt ttagtttgat aatttgtgag aagtatacca agtattatac
    15541 ataatattga taaagaacca atcagtaaca ttttagaact ggtccattcg ttaaacaaga
    15601 ttacagctaa taatgtcgta aaagttaatt gtgaaccatt tgaaattggc attactttag
    15661 atacactagc aatttgaatt gctttaaact gcattaattg tcccaaactc cagaatatgc
    15721 cagaaatcat acttatacaa aatgaaaaaa atgtaatttc aggatgtata accagagtta
    15781 ttatagtgga aaatataaac gcacttatgg atgtacctaa aagctgttca tgaggagaac
    15841 ttttctttag atttgcaact atgggcatca atccccatcc cattacagga agtaaagcaa
    15901 taattattgt cagcattaaa ctatttcctt tcatattaaa tttagacagc ttttaattta
    15961 tcatctaaaa ttaaagtgtt caatacataa aaattaccgt atttaatcag gaaatattag
    16021 tagtttttta gaaaaacatt ttccattaaa ataaagacaa agggaaggag taaaattgaa
    16081 aatgttaact gatatgattc aaaatcgtga aattaaaata ataaagtttt tattaaaaga
    16141 aggtcataca actgtaaaag caatagcaga tgatttagat gtttcagaaa aaacagtttc
    16201 aaaatctctt aaagaagtag aagcagtgct taaaaagata ggtctttctt taataagaaa
    16261 acctaagata ggtgtttata ttgatggaga tttaaaaaaa atacttcctt acctagataa
    16321 taaaggaagt caaattccta caaccagaga ggagagagtt atctatatat attcagtact
    16381 tttaaagagt aatgattata ttactataca acaactttct gatgaactat atataagtcg
    16441 tggaactatt gaaagggatt tagcagaagt tgaaaaactg ctaaaaaacg aagggatttc
    16501 catatataag aaacctagta agggaataaa gttaaatata agtgaaagag ataaaagaca
    16561 acttactgct aaatttatac ataaattttg gagtagaaac tggtatatta agcaagagca
    16621 agaaagcttt tatcaagcat ttgaaaagat acaagcagat gtaaatggta ttttttcgga
    16681 agatgattta tcaataatta ttgatattct taggaatttc agcagagaaa gaaaatttga
    16741 gttctctgat tatgaatttc agtcattagt tattcatttg gcaatagctg tagagagaat
    16801 tagaaaaggc gaatatatag aagaaagttt gtatactggt aatatagaaa ataatcaaat
    16861 gtcaaatacc aattatttag caaaacaatt agaagaaaaa ttttcaatat tattaccaaa
    16921 atctgaaatt ggatatataa atttacattt agtagcgtct gaccaacata gagatactaa
    16981 tgaactaaaa aatacttcaa ctaatccttg tgagacaagt acaaataata tatcaaatct
    17041 tcgggaaatt ataaaaaata cattgtatga gacagcttat gacaaggatt taattgatgg
    17101 attaacttca catgtacatt catcaataaa tagactgaaa tatggactta gtattaaaaa
    17161 tccatatgta aatacaatca aacaaaactt ttctttatca tttgagcaag ctttagattt
    17221 aaagaaagta attgaattta tatatgatat taggataaat gatgatgaat gtgcttatat
    17281 agcattacat tttgaagctt ttagagaaag aatgaaagaa cttccacaaa atattagagt
    17341 aattctagta tgcagtacag gattaggttc atctaggtta ttgtctgcaa gaataaaaaa
    17401 atactttcca atgataaaga ttgaaaaagt actttccgta caagaattag tatccagtaa
    17461 aattgatgca gatttagtaa taagtactat ttatttagag ttagaaacaa ttccaaccat
    17521 agtagttagt cctattttaa atgaaagtga tataagaacc ttggaaagaa atatacaaaa
    17581 tgtttcaagt tgtacttcta agaagtataa atctttcaga aatttaatct ttgaagaaaa
    17641 tatattgttg aatattgaag cttcaaatta tgaagatgca attaatcata taacagataa
    17701 cctaataaaa aaaggttttg caaaagaagg tatagctaaa agtgcaattg agagagaaaa
    17761 tttatcttac acttctttcc aatcaatagc tacacctcat gctaatccta gttatattaa
    17821 aaaatctaat atatctgttg caacgttaaa aaatcctatt acatggggaa atgaaaaggt
    17881 ggaagttatt ttctttattt cattagaaaa tgacaaaaac ctagagcttg atgaaatata
    17941 tgaagttttt tatgacttta ttgacaataa aaaaaatata aatgacatat taagtgcaac
    18001 ttccacaaag gaagtgtacg atttgctagt ggaggagagt atatagtgaa aatatcagat
    18061 gtattgaaaa aagagcaaat tgtttttaat cttgatacaa atacaaagga agaaacaata
    18121 aaaaaattaa gtagtatatt tgttgaaaat gggattgtgg acaatgaaga agaatatgtt
    18181 aagtctgttt tggaaagaga agaacattca actacaggta ttggtaatgg tattgctatt
    18241 cctcatggaa aaagtaatgc tgtcaaaaaa tcttctataa tatttgcaaa gactaagcat
    18301 aagattgaat gggatgcttt agatgaaaaa ccagtagata gtattttctt attggctata
    18361 agcaatattg ataaggatag caatcatctt gtactattat ctaaattagc aactaaactt
    18421 atggatgatg acaatgtaga tgcactaaaa ttagccaatt cagaacaaga aataatcaat
    18481 atatttagtg aagaaggaga gatgtagaaa tgaaaagaaa aattatagca gttacagcat
    18541 gtgcaacagg agttgcacat acatatatgg cagctcaagc gttaaagaaa gcttcaaaaa
    18601 agatgggtca ccttataaaa gttgaaacac aaggagctac aggaatcgat aatgagttaa
    18661 ctacaaagga tgcacaaatt gcagaagtag taatatttgc agtagatact aaagtcagaa
    18721 atgctgaacg ttttgaggga aaagaaatac tagaagtacc agttaatgca cctataaagg
    18781 atgcagagaa agtaataaat gatgcactaa agttaattga cactaaataa atggagggaa
    18841 atataatgtt gaaaaagata gtctctgagt taaaaaagca tgtcttaact ggaatctcat
    18901 atatgattcc attagtaatt gcaggtgcta tgataatggc gatatctcgt gtaggtggtt
    18961 ctttctataa tataccagat atatgggatg ctaaatatgc agaaagtgct agtagtattg
    19021 ttagattatt acatgattta gatgggtttg gaggtactgc attaggatta atgtttcctg
    19081 taattgctgc atttatagga ttttctatag ctgataaatt agctattgta ccaggtcttg
    19141 ttggaggtat gattgctaaa gatataggtg caggattttt aggagctttg gcagttggtc
    19201 ttatagcagg atatacatgt ttgtttatta aaaatcatgt taaattacca aaatcagcag
    19261 cttcaatagt accaatattt atagtaccag tatttgggac attaatcact gttgtattaa
    19321 tcaattatgt gataggtata ccttttgcca cattaaatac tggattagaa aattggttaa
    19381 atggattatc tggtacaaat cagatattaa tggcagctat tataggggct atgatggcag
    19441 ttgacttagg tggaccagtt aataaagcag ctttaacaac atcacttgca ttattaacaa
    19501 gtggaattta tgcgcctaac actgctgcaa tggtaggaat agttatacca ccactaggat
    19561 tgggacttgc tactatacta gcaaaacaaa aatataataa acagttacgt gaagctggaa
    19621 aatcatctct tataatgggt ttaattggag taagtgaagg agcaattcct tttgcagtag
    19681 aatctccatt aaaagtaata ccttcatgtg taattggaac agcaattgct tcagctatgg
    19741 cagttggttt aggttcagta aatgcaactc caattagtgg attttatgga tggtttacag
    19801 tagagaattg gccaatgtat gtgttatcaa tagcagttgg aacagtaatt gtagctggat
    19861 tagttatagt attgcgtgga aatccagtga ttgaggatga tgaatttgaa gatgatgatt
    19921 ttgatgaagc agagtgggaa tcttaaaatt taataactat ttaagacgtg ttataagcta
    19981 tattcaatat gaatcttata ctaaataaag tgttaaacat tcagtttaga cttaaatata
    20041 aaagataaag aacagaggag aataaatgat aaaagcacat attgttaatc atacacactg
    20101 ggatagagaa tggtatttta cttctggaga tgcattagta cttagtgaac aactatttac
    20161 agatgtaatt gatgaattag aacgtaatcc agatgtaagt tttgtacttg atggacaact
    20221 ttctattttg gatgattatg tacaattaca caaagaaaaa atagaaatca ttaaaaagtt
    20281 aataaaagaa gatagactac atattggacc atggtttact caaactgatg cattctttgc
    20341 tagaggagag tctattttaa gaaacttaat gattggaatt tttgaaagta aaaagtatgg
    20401 taagtatatg aaaattgggt atttgccaga tacatttgga tttaatgcac agatgcctat
    20461 actattaaag catgtaggtc ttgataatat attcttttgg agaggtatac atcttggtaa
    20521 acaggttcaa tcaccatatt ttaagtggaa aagcttaaat ggagaaagtt atatatatgc
    20581 agtaaatatg ccacatggat atggaactgg tatgctttta gagccttcat taaagtatgt
    20641 taatggacgc ttagacccag ctattgattt tattaaatca tatactgatg tagatgaggt
    20701 gttaatacct tctgggaatg accagttaaa tataataggt gatttcaaaa ataaaattaa
    20761 agcgattaat gatatcggaa agtattcata tataacgagt tcatatcaag agtttttaaa
    20821 atatataaag tctatagaat cactagaaag ctatagaggt gaatttagag aacctgtatt
    20881 agcaagaata cataaatcaa ttggttctag tagaatggat ataaaattag catgtgataa
    20941 actagaaaac aagctgatta aaagaataga gccattatta gtaattgcta aaaagagtaa
    21001 aattgaaata agcaatcagt tacttataaa tacatggaaa aaacttttgg aaggacaagc
    21061 acacgatagt ttagctggat gtgtaactga tactgtaaca gatgatattc ttcaccgtat
    21121 aagagaagca aatgaaatat gtgacagtat tgaaaatact attgtaaaaa agatttcaga
    21181 agggcttaaa ttatctaaaa atgatatttt agtattcaat acagaagcta agcgttttaa
    21241 tggatataaa gagatacaag ttgtaagtga tagtaaaaat atttatttta aagataattt
    21301 agatgctact ataattgaag aaacttatgt aaaaccgaga gaaaatgtat tagaagaaac
    21361 acctgctggt aatatattta ttgaagaacc aggatattat atattaaaag taagaataaa
    21421 tatacagctt cctgcacttg gttataaagt tgttagtttt gaattaagtg ataaagaaat
    21481 ggtgtcactt gataaatcta atgacacttt tatatctaat gataattata agataatata
    21541 tgaagatgga agcttaaatt tacaacttaa agatggaact tacatatcaa actttttaac
    21601 attaaaagat agtggtaatg caggtgatac ctatgacttt tctccactaa aaaatgatga
    21661 ggatataaaa ctttcgtttg ataaagtgta tacagaaaaa gctttaggat atgaaaaaat
    21721 ggtggttaaa ggtactactt tactaccact tacattagaa gatagaaaaa acaaatatct
    21781 taatgggaaa ttaaatgtaa aagtaagtat tgtcttatct aaagaaaacc cattgatgga
    21841 tgtaaaactt tgtgttgata acacgatata taatcataga ctacgtgttc atataaaaac
    21901 tgatataaaa gataataaaa acatagcatc attgccattt ggatatataa caagagaaaa
    21961 tggagtttta gacaactggg aagatattta cagtgaaatg cctatagatt tagaaccttt
    22021 ggaaagtaat attacgctta caaaccaaaa tagaagttgt actgtattta ctagaggaat
    22081 aaaagagtat caacatattg aagatgaaat tgcattgacc ttacttgcta ctacagatga
    22141 actaggaaag cctgatttat tatatagacc aggacgtgct tctggagata caactaaaaa
    22201 aggtcatata agaattaaaa cagataaagc tcaaatgctt aaggaattag aattttcatt
    22261 tgcaatatat atggattcta aatcatttga tgaattggaa attgcgaatt taacccacaa
    22321 ttatctaaga gaatgtgtaa attatcaatt acaggattac aatttctttt tatatcgtat
    22381 agataataag attcaaaaat caattgtcaa taaaactgta agtagagaat tagaaataat
    22441 atctttacca gaaaactatc ttatatcagc atgttatcct tcttattaca gtaaagataa
    22501 atttataata agagtggaaa atccgagtag taatagaatg atattggatg agcaaatatt
    22561 taaaaataga aatgggaaaa ttgtaaatgc aatagaagat gtagaagaag aacaggtata
    22621 tgaaatagca ccttttgacg ttatttcaat actattggat ttataagtgt aaaagtaagt
    22681 ttattgttta aagtctgaca gatattaatc tgccagactt tttaatttgt ataaatttgg
    22741 gtaaatatta atgaatggtt ttagtattta agtatgaatt tagtatttaa tatagaattt
    22801 attgaagtag aataattagt ttaacaggat aagcagttta aataaagaat tattatatta
    22861 gagtgatttt atatataatt taaaataata aaattttaat aa
//
LOCUS       DAMJXI010000057        22743 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.059, whole genome shotgun sequence.
ACCESSION   DAMJXI010000057 DAMJXI010000000
VERSION     DAMJXI010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22743
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.059"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            89..1525
                     /locus_tag="PC465_002792"
     CDS             89..1525
                     /locus_tag="PC465_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDF2650078.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKGSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYDSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIVFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWM
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVNRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESNLVKIFANNFIEIVN"
     gene            complement(1617..3491)
                     /gene="asnB"
                     /locus_tag="PC465_002793"
     CDS             complement(1617..3491)
                     /gene="asnB"
                     /locus_tag="PC465_002793"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HDF2650079.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            3694..4368
                     /locus_tag="PC465_002794"
     CDS             3694..4368
                     /locus_tag="PC465_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HDF2650080.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            4481..5017
                     /locus_tag="PC465_002795"
     CDS             4481..5017
                     /locus_tag="PC465_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDF2650081.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(5183..5803)
                     /locus_tag="PC465_002796"
     CDS             complement(5183..5803)
                     /locus_tag="PC465_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDF2650082.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(6117..8255)
                     /gene="vanT"
                     /locus_tag="PC465_002797"
     CDS             complement(6117..8255)
                     /gene="vanT"
                     /locus_tag="PC465_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HDF2650083.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGVKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            complement(8273..9079)
                     /locus_tag="PC465_002798"
     CDS             complement(8273..9079)
                     /locus_tag="PC465_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2650084.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            complement(9076..10176)
                     /gene="vanG"
                     /locus_tag="PC465_002799"
     CDS             complement(9076..10176)
                     /gene="vanG"
                     /locus_tag="PC465_002799"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HDF2650085.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNNDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            complement(10437..11519)
                     /locus_tag="PC465_002800"
     CDS             complement(10437..11519)
                     /locus_tag="PC465_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2650086.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFMNHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIVGNL"
     gene            complement(11569..12270)
                     /locus_tag="PC465_002801"
     CDS             complement(11569..12270)
                     /locus_tag="PC465_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HDF2650087.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            complement(12704..15235)
                     /locus_tag="PC465_002802"
     CDS             complement(12704..15235)
                     /locus_tag="PC465_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HDF2650088.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNIKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            complement(15343..15960)
                     /locus_tag="PC465_002803"
     CDS             complement(15343..15960)
                     /locus_tag="PC465_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDF2650089.1"
                     /translation="MCKKTYLLVVSMLIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIMTPQQAMEIALKEQNG
                     IVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            complement(16322..17206)
                     /locus_tag="PC465_002804"
     CDS             complement(16322..17206)
                     /locus_tag="PC465_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HDF2650090.1"
                     /translation="MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLII
                     GILILSIGFKIIKKFVNHVMLLLSKRDIDLTLRKFLKSLLLSVLKVAVIIIVLEYWGM
                     SLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIG
                     LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKD
                     IVNNHKLIINEPEPFIGVVEHGDNAIKFATRVWCKTEDYWTIYLDLLEEVKVKFDEEG
                     ITIPYPKMDLTVKELNKI"
     gene            complement(17397..18647)
                     /locus_tag="PC465_002805"
     CDS             complement(17397..18647)
                     /locus_tag="PC465_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2650091.1"
                     /translation="MKSYTKAKWSVWGIITFSFVLVLFLRMSTAVVSDNLANELGFNS
                     IQISNIASFCLYAYAFMQIPAGILIDKYGARKISSLGIIMASLGSILFGLIQSIELAY
                     ISRVIVGAGTSVILLCILKIQGRWFNKSEFASATAKFSFVGNLGGVLATFPLVFLSEL
                     VGWRNSFLLIGIIGVVIGCFMYIIVRDTPKEYGFNVDTEPYEKSEKVNIVDGIKSVIK
                     NKSTWYNSMIMFSFVGLTSAFISLWGVRYIMDVYGVSKSFSAFIVSFFTYGFIFGSII
                     MDFVFAKIRSSKFNIIKFGAMIDLFIWIVIVVVYQVKPPIIVLPISFFIMGCIVMSHL
                     QVFNDTKYKNKEIYSGLATSVINTFEFIGSGIINLIIAISLQVNSYNIVDGYKKGFVV
                     FIVLSIITIVSSHIGVKNDDFKAI"
     gene            complement(18869..19633)
                     /locus_tag="PC465_002806"
     CDS             complement(18869..19633)
                     /locus_tag="PC465_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2650092.1"
                     /translation="MLGKLLKYELKASGRIFIPLYIAILIVAVFNGIFMNTNILQVQG
                     IGILVLTSLFMALGVLTIVVTIQRFRKNLLGDEGYLMFTLPVSTSSLILSKCITALIY
                     AVLSFIVAVFTFGVLMLFGTSGILLPEILDLFNTSFKWISENFLDILLLVVVMFISYS
                     SFILLLYTSISMGQLPKFNKHRNIVAFASFIAINIVISIVGDAVGSILPNEDTNMVYH
                     LYQSPSFMLAILGSLVVAIALFFATKFILDKKLNLE"
     gene            complement(19627..20352)
                     /locus_tag="PC465_002807"
     CDS             complement(19627..20352)
                     /locus_tag="PC465_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2650093.1"
                     /translation="MDKNISNVSQDGIVEFKGVNKSYGTKNVLKNIDLNIPKGKIVGL
                     LGPNGSGKSTMIKLMNGLLQPDNGEIMINGMKPSIDTKKIVSYLPERTYLNDWMKVSD
                     LLKFFYDFYSDFDVRRANEMIKSLDIDVNEKLKTMSKGTKEKVQLILVMSRNASIYIL
                     DEPIGGVDPAARSYILKTILKNYSEDSTLLIATHLISEIENICDEIIFISKGEIVLQG
                     DVEAIREEKGKSIDALFREEFKC"
     gene            complement(20354..20722)
                     /locus_tag="PC465_002808"
     CDS             complement(20354..20722)
                     /locus_tag="PC465_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2650094.1"
                     /translation="MEWELDNNKPIYIQLVEHLKLKIISGEIKIGSKLETVRALAEDA
                     EVNPNTMQKALTELERQGLVYSQRTKGRFVTDDKEKIKAMKEEIANVEINTLKVTLEK
                     LGYDRDEMLKLITENLKGEL"
     gene            complement(20898..22442)
                     /locus_tag="PC465_002809"
     CDS             complement(20898..22442)
                     /locus_tag="PC465_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF2650095.1"
                     /translation="MRNLQKKLMFFLFICIILQITYTTPVYSLCKLYKNNSINNFESI
                     VSNNQLISKHAIQIILIMAIICVILIFYIIYDKLNFKIKLQRIAYTDNLTGANTIDKF
                     VIDANKILCKNTQVKYALLYIDIDKFKYINDLFGYEVGNEILRNLTKIIKSNIFEEEM
                     FARISADNFIIIMKYIEEEDITKRLKTIFEELDLFNNNQEEKYKLVLSCGIYFILPED
                     RDINSIIDRANIPHKMAKGGHKSSYAFYDNKIHDQEIKEKEMENTMFSSLENKEFIIY
                     LQPKIELNTGEIQGSEALVRWKRPDKGLIPPNEFIPFFERNGFVINLDLYVLEEVCIY
                     LRKWIDAGINPVTVSVNVSRIHLYCNNFIETYKNIIDKYNIPAKYIELELTESIIFDN
                     FDILIDIMNNLKKIGFLISMDDFGSGYSSLNMLKEIPMDILKLDQKFIMETYNSKRSK
                     IIVTKVIEMAKELGMKVISEGVETEEQFKLLKEVKCDMAQGYLFGKPMPIEEFEHLIV
                     SNLIRG"
BASE COUNT         7840 a         3810 c         2376 g         8717 t
ORIGIN      
        1 ttttattttg aaactacaaa attattgtac tatattgttt taagttgttt tataatagat
       61 tatatcatct tattatagga gaaaaaatat gatttgtact attaaaccat taaagatttc
      121 aataaaaaag tctactgaac ctctaattga atttatatct gatactacct ataaaaataa
      181 gggttcttca tatattaaag aagtctactt tacaagatat ataggtgttg atgattcaat
      241 tgataaatac atagaaaaaa ttaaaaatat agatacttat ttttttaata atcctacaat
      301 tccctatatt agattaaaca atctaaaaat aaattttgac aaagaacaaa cagataagat
      361 gcttaaaatt tttaatattt atgatagttc taagtttaac agttgggatt tatataatat
      421 cgactttcca tgtaaaatag aaaatgacac cttaaattgg actaaaaaga ttgtatttaa
      481 aaatacttta gatttatttt ccacaagtat gccaaattgt acatcctcta tcatcaaaaa
      541 ctttgcagtt aaacttttgt gttggatgga ctattttcta cctaaattat tttataacaa
      601 ggtgaagact actatttcac caaagatagt atactttgga aatattaaaa ggcaagaact
      661 ttttttctta tattttttat cacaacttgg gtgtgatatt ttatatataa atccaaataa
      721 agatattctt gatttatatc ctgaatgttc aaaattttct actctatttg aactttctag
      781 gaagactcca aatatattag aaataccttt tgaaaggcat attacaaata taaattacag
      841 tgaaaatacc aataagactt ctcctactac gaataaacct aactctaaaa atacacttaa
      901 taacacaaat ctaacatcta aaaaaattgt acaagatgag gaagtagaac tttcttatga
      961 agaccttgca aagttatcag cttctgttgt tatgattgtt gtgtgcaata acgaaaataa
     1021 accgtttaag agcggttctg gagtagtaat aaataatgaa ggttatatac ttacgaatct
     1081 tcatgtagtc aatgatgggt attcattttt agttagattt gaaaatgatg ataaagttta
     1141 tacatcttac caaattataa aataccattc agattatgat ttagctgtga taaaggttaa
     1201 tagaaaatgc aagccaatac ctgttaaagt cagtaaaaaa cctgtgagag gtcaaaaaat
     1261 agttgcaatt ggaagccctt taggtctttt taatacagtt tcagatggaa ttatttcagc
     1321 ttttcgtgat tttgaaacgg ttcaaatgat acaatttaca gctccaatct ctagtggtag
     1381 ttcaggagga gctcttttag atatgtttgg aaacttacta ggattgattt ccgctggata
     1441 tgatgatgga caaaacttaa atttagctgt tgaaagtaat cttgtcaaaa tatttgccaa
     1501 taattttatt gagatagtaa actaatcaat caaagttcta cttatcctat tccataataa
     1561 tcaggagggt gaaaacattg catgcttttg ccctctgatt aatattgaaa aaagtattaa
     1621 tactcgacat ttttatgctc aataaataat tgatgccata gacaaaatgt aaatatagtc
     1681 catatttttc tcgaattatc tctatgacct ttaagatgcg tatctaaaag ttttattgca
     1741 tattttttat ctataaattc atctacattt gaattataaa tagtttcctt tacaatatcc
     1801 cctagagaat cttttaacca aactcttatt ggagttggaa atcctaattt tttcctttga
     1861 acaacatgtt ctgggactat ttctctaaac gcctctctaa gtaaaacttt tgtattattc
     1921 ttatttattt tttgctccat tcttaaattt tttgctacat caaatacatc tttatataaa
     1981 aatggtactc taagttcaac ctgctcagct gtagaaagtt tgctaatttt ttgaagtata
     2041 tcgccttgaa gccatgtatt cacatctata tgttgcattt tacttatata atcgtaatta
     2101 tttttttgtg catctctata caaattagac aacaggtatt catatatatt cttttcctta
     2161 tacttaaaaa agaatctttt tacttcgctg ttttcaaaaa cttttgcatt tcctatatat
     2221 cttttttcta atggtgttgt agctctataa agataatttc ttccttttat gtttggcata
     2281 agttctgaaa ctcttcctaa tatactttta atataagtag gtgaattgac aactgatttc
     2341 atagtactat actctttata tatattatat cctccaaata attcatctgc tccttctcca
     2401 gacaatgcta ctttaacatg tttacctgcc tctttaatta agaaataaag acctacttct
     2461 gaagggtctg ctatagggtc atccaaagaa taaattacat tcggtaatga ttttatatat
     2521 tcatcttgtg ttatattaat ctggatattt tctataccta acttatcagc tgttttcttt
     2581 gctacttcta attcactata tcctttgaca ctaaagcctg cagaaaaaga ttttatattt
     2641 ggattaattt gtgaagccac agtagttata atagatgaat ctattccacc agacaaaaat
     2701 gttccaattt ctttctcctc ttccatatga gttactattg aatctactac tatatttctt
     2761 atatcatcct cgttcacatc tctattgcct aagtgatttt tagtataaaa aaattttgta
     2821 ctacttctaa actcaagttt attatatctc tttaaagata gtataccatt ttctacccta
     2881 aaatagtgac ctgctggtat cagccttatt ccttgtatca tagtatcttc aggaagtaca
     2941 tattgaaatg aaaaataact ttgtaagctt ctttcattta tatttaaatt tttcatatat
     3001 tcaagtaaaa acttatactc tgaggaaaaa attattgcat tttccttatt tatataatag
     3061 agtggtttta tcccaaataa atctcttgct ccaaatatac tttcattttc tctatcatag
     3121 attataaagt tgaacattcc tttaatctta tgtacacaat tcttaccaaa ttctatataa
     3181 gatgccaata agacttcaat atcatcattt gtagtaaaat tgtgtccttt tttaattaat
     3241 tcttctttta tttcatgata gttatatata tttccattaa aaacaataac ttttccatct
     3301 ttttcaaatg gtttatttcc ataaatagca tcaattacat taaatctttc aaaatcaaaa
     3361 gttttttcct catccttata ctctattcta ctagaaagtc ttgtattatt tacagattct
     3421 tttattttaa atttaatatc ttctttttta gatatatcac ctttataata aattgaaata
     3481 ttgccgtcca tataatcaaa attcctttct gtcctttagt cttattctat atttcatagt
     3541 tttgtctttg gctttaaaac ttattcaatt taaaatgaaa ttgctattaa attcttataa
     3601 attatctgtt aatatttcat atttttttta tttctagaaa tactatatta ggaggtgatt
     3661 tttatgaaga aaaaaatatt aataccagtt attatgtctt tatttataat ctcacagtgc
     3721 ataacttcat ttgcttttac acctgaaaat aacaaattta aggttaaacc attaccttat
     3781 gcatatgatg cacttgaacc ttatatagat aaagaaacaa tgaaactgca tcatgataag
     3841 cattatcaag cttatgttga taaattaaat gctgctcttg aaaaatatcc tgagctttat
     3901 aattattctt tatgtgaatt attgcaaaat ttagattctt tacctaaaga tattgctaca
     3961 actgtaagaa ataatgcagg tggagcttat aatcataaat tcttttttga tataatgaca
     4021 ccagaaaaaa ccataccttc tgaatcttta aaagaagcta ttgatagaga ctttggttct
     4081 tttgaaaaat ttaagcaaga gttccaaaaa tctgctttag atgtctttgg ttctggttgg
     4141 gcttggcttg tagctactaa agatgggaaa ttatctatta tgactactcc aaatcaggat
     4201 agccctgtaa gtaaaaacct aactcctata ataggacttg atgtttggga gcatgcttac
     4261 tatttaaaat atcaaaatag aagaaatgaa tacattgaca actggtttaa tgtagtaaat
     4321 tggaatggtg ctttagaaaa ttacaaaaat ttaaaatctc aagattaatt aaatattaaa
     4381 atccttttga aaaaaactta tgtttgctat ataatataat aaaagatagt ctaaatttac
     4441 caatataatg tttatagtga cgattcagga ggatttttat atgataaaag aaacacatga
     4501 aaggggaggt tatatattcg cacttttgat actccccttt ataaacaatc tatacctagt
     4561 taaatacgat attgcatata aaatagtatt aattataatt tatatttatt ttgcatattt
     4621 aggttcttta tttccagata tagatatgag aggttcttac ataagtaaaa aatttatgtt
     4681 aatatacaaa ttatttggaa gtaggtttag acatagaggg tttactcaca gtctaattgc
     4741 cttattactt atttatagtt tttttaaatc tctgacaatc ttcactaaca ataatatagt
     4801 tttctcatgt ttgtccagtg ggtttataat aggatatcta tctcacttgt gtcttgacct
     4861 tattactaaa gaaggtattg aattgtttta tcccattacc ataaacattt ctttactacc
     4921 tataaaaact aactcaaaaa cagaaaaatt catatctaag ctattaaatt tcatagttat
     4981 ttttttgatt ggatatcaat tttatatttt attatagttg tagaaaaaat aaataacaat
     5041 attttgaact aagtataaat aagttttata tattttagtt tacaaaagaa ctaaaaattt
     5101 tgtaccttaa tacaaaaaat aaaacgtatc ttaaaataat ttagtactaa atcattttaa
     5161 gatacgtttt atttcgtaca agctaaatca ttttatcatc tttatcattg tgatgttttt
     5221 tatgatggaa atcataatta tgattttcaa gatttttatt tactctattt ccaatcttcc
     5281 atgacaaaaa caccaataat ataaatgatg ctatctttaa aggacttgtt ataaaacctt
     5341 ctatatcact tgccacgtaa cttataacta taaacattac aaattttcct gccaacattg
     5401 ctggcacaaa atcttttaaa tcttttttac caaaagctga tgcgatagta actaaacaac
     5461 cgggcataaa tggacaggca tacgctataa ataataactt aaatccctgt ttatccatcc
     5521 aacttattgc tttttcagtt ttactatttc tcaacttatt aaaaagctta ctatcattaa
     5581 atctgcttat taataagaat aatgaagttg tcccaagtcc tgagccaatc catgataaca
     5641 aacatccaat aaataatcct tgtattgcag catttgctgt aactatagca acaagtggta
     5701 aggctggtat aaagctttct ataaatgcac ttaataagcc gattattgtg gctaacaccc
     5761 aataattttg agtcaaatca agtaattctt gtatatactg catattgctt ttcccctttt
     5821 ttaactttaa ctattattat atactctata tgtttattat ataccaatct caaaaaatga
     5881 atctaatatt aaaaagtaaa taatctatat aagtttacag ttaaggtata attattttat
     5941 tatatattat aacaaaaaag gtgatgtttc aaaataaaaa tctgaaacat caccttttta
     6001 tagcttaaat tgtcatgtaa gttataaaaa atatatatta gacataatat tactaaaaat
     6061 gtctagtcag attaaaataa attacacagt acaacaaata ttactattta attgagttac
     6121 ttctttataa catttaacct ccttcctact ctgctcaata attcatttga tatactacac
     6181 gagttatttg caacttcaga agcagataat tcagataaat tatctcttcc tattattatt
     6241 gccgtattac caacttctac attaggtata tctgtaatat caacagcaag ttggtccatg
     6301 caaattcgac ccactattgc tgctctacaa ccatttatta ttacgtaact ttttccacag
     6361 gataaatttc taggtatacc atcggcatag ccaatagata atatagcaat tacgctatct
     6421 ctgcttgcaa taaagactct tccatatcca aaactatcat ctttttgtat ttttctaata
     6481 agaattactt gtgattttaa ggataaaaca ggtcgtaaat caagttgcaa tttagtcgta
     6541 tcatttggag aacttaatat cccgtataat gcaattccaa ttcttacata attacactta
     6601 agattgggat aattaaaaaa accataacta ctttgaatat gtactttagg aatttttaca
     6661 ccttttttta acagaaaatc aattaactta taaaaacatt caatttgttt atttgtaaag
     6721 tctacatctt catctttcag actatctgaa acacacaagt gtgtaaatat gccacatata
     6781 tctaagtatt ttaatttaaa tgcctttaaa attgacctca catcattaac atcaaaaccc
     6841 agtctgtgca tacctgtatc aattttaatg tgtgatttta tgttgtattt ctgtttgttt
     6901 aaagagatag catgattaag gtcaataaca ctctgtgtaa gattgtattt atgaagttcc
     6961 tttgccctta ttgggttagt atatccaaga atcaatattt ctcctagtat tccatatcga
     7021 cgtaaatcaa tcccctcatc tattgttgct actgcaaatg cttttacacc tatttggttt
     7081 gcacaagtcg ctacttcaaa agcactatga ccataggcat tagcttttac aactgccatc
     7141 aattcacaat cttctggcat agctttttgt atcatcttta cattatgttc caaattattt
     7201 aaatcaattt caatccaagc tctattggta tttaccttat gttctccttt caagtctttt
     7261 tttagaggtt taagaatcaa tataataatt atagaagcta taaaagatgc tatacttacc
     7321 actatataat gaataaggct attgtcaacc aagacagttt gtattccgaa tattttagaa
     7381 aacatacgaa taacaacaat catcatagga tgtataatat aaataattaa tgatgatgtt
     7441 cgcaataacc tagctcgaga acctttcaaa aatgttaagg ctgtaaataa gaaatacata
     7501 catggcaata acataatata catgctatca tgacgctgta cccctagttt atgtaaaaac
     7561 attccctcac ataacataag taagaatgat ataagaaatc caatcaagct atttttagtt
     7621 gacatataat tagatttatt agatattatt ccaccaagta tgaaaaatac aggtgcaaaa
     7681 aatatgccat ttcgtgtata atctgatact tcaaaaatat acccatataa attctttaat
     7741 agtggtattt tttctaaaaa accataataa ctatcaccaa acataccaat tacataaata
     7801 acaatagtga ttactagtga gtactttaaa cctagttttt ttacaagaaa gtatgcaata
     7861 cttgcaccaa taattgatgc aggaagatac cataaatgat ataaagtccc atcaaataca
     7921 atgtccttaa taatattggg cactaaatta ttcatggaaa aatatccagt gtaaatattt
     7981 aagggaatat aaattacaat agctatcccg taaataaata atacattttt tagaaaagat
     8041 ttcagtttat tacaattata attatatgtt gaaattagaa aaaagcctga tagcataaaa
     8101 aagaatggca cagcaatacg agcaattata ctagttaaca caaagtcagc cattttacta
     8161 tatgataata atggagatgt atgaattgca attataagta atgcagctat aatcctaaaa
     8221 taatcaagcc ctgcataaga tttattccta atcattcttg ttcctccatt tcttagtcct
     8281 ttctatttct ccaaaatgtc acaataaaac catccttatt gttacccgat atttgatata
     8341 cacattgttc aggtatagag attctcactt cttctttagt atgaataggc acataaaaga
     8401 tttctataat tttttcttta tcttctattt ttaaacaatt tgtatacgaa aatctcttaa
     8461 tatattctat atattcttca agagcgagat tcattttatt gataatctca gaatgcggat
     8521 atcccacata acgaaaatgc catggttctt gagatattcc tgttatttct tcttttttac
     8581 actgataacg ctctataaaa ccataatgta gtgctgcctt acgaaactca ttacaaatac
     8641 cattataagg aaattcaggg cagataaaat ctataacttc tttctttaac cctaaatcaa
     8701 tagcaagccc tgtctgatgt tcactgtgat ttggaagtgc tacaaacttt ttagtaaagt
     8761 cttttccatt gtcacgcaga gaacttgaat atatatcttg ttgttcctct gcagtacgat
     8821 atccacttac aggtactatt tcatttattc cacatatact ttttaaaata ttttgtaaaa
     8881 tgtttgtagc ttcacgtttc ataagaatac ttggaaacct tgtatctaca ggaattaaat
     8941 ctatatcttc agatgtttta actggtaaaa aagcatttac tagaattaga ttcccatcat
     9001 aaactttatc tttagtcaat aagatagtat ttgtcatttt atcttcttta tttttatcta
     9061 ataaaatatt attcatcatt ttatgtacac ctcaattatc ttgtccaata tttcttcaaa
     9121 agacagtcca atacctttca tcatatttgg ataacgacta tgagaagtaa agccaggaat
     9181 tgtattgact tcattaaaaa taatttcacc agatggagtt aaaaacatat ctactctagc
     9241 aaatccagaa catccaagag ttctataaat aatttttgct gtctcttgta ttcttttctc
     9301 acaatccaaa tcaattctag ctggcatatg aatttttgaa cttttcaatg tatatttttc
     9361 tgtataatca aaaaatcctt ttgacaattc tatttcatct actcttccaa caagtaagtc
     9421 attgtttcct aaaactgcac accctacctc aaaaccatca atattttcct caattattac
     9481 ttcattatca tgttcaaaag ccaagtctac tgctacttgt aactcttctt ttttataaat
     9541 tttactaata ccaaatgatg aacctgcacg cacaggtttt ataaataatg gataagttaa
     9601 gtcttttgac agttcagcca cattaaattt atctgagtat tttagtaata ttgattttgg
     9661 tactttaata ccttctgaat gaacaagttt atgtgatttg tctttgtcca tacataatgc
     9721 tgaagaaaga gtaccacatc caataacctg tatacctgcc aattcaaata acccctgcac
     9781 tgttccatct tctccatttt ttccatgcaa tacaggaaac acaaaatcaa gtttagtgta
     9841 tttaatatca ttttcacatg attcaatagc actatttgga atatgattct gagaaacagc
     9901 atcaggaatt aaaaattcaa taataccatt tttgacacgg ttctgcgaaa caataactgg
     9961 aattatatca gtatcccttt caaaccaagt gttattctgg atattattat aatctccaat
    10021 ataatgatac caattaccct cccttgtaat tccaattggt ataatatcat atttttccgt
    10081 attcaaattc tcaagtactg caaaagctga ttgtaatgat acatcatatt ctgttgagtt
    10141 tccaccaaat ataactgcaa tttttttatt attcatcttt gattctcctt tgttgattta
    10201 tttattttta tacaatctac agaaacatgt taaaatactt tttctatttc aaatccaatc
    10261 aaccttcact tacaattgca tctgttccac ataatatatt ttcacatttt tctattgata
    10321 taattactgt atcaaaataa aagcactctt gttttgatac agtaattata tcaataacaa
    10381 gagtgctctt tatttattta tcctaaagaa tttcctattt ttttatactt aaattcttac
    10441 aaatttccta caatcggaat aataacctta aaggtaatta tattgttctc gctatgagct
    10501 gttattgtcc cgttatgaag ctccactatt tctttagcta tagcaagtcc caacccagct
    10561 ctaccactgt ttgaattacg agatgtatcc aacctgtaaa attgttcaaa aatacgctca
    10621 agtttttcct ctggaatcgt attgctatga ttcataaatt taagctttat ataatcatcc
    10681 tcctgtacag ctgttatttc aatagtagta tcttcaaaac tataataaac agcatttcgt
    10741 aataagttat caaatacacg ttgcatttta ttaacatcac accttatcat catatttggt
    10801 gtaacattca gtgtatattt taaattctta ctcatcaaag taggtttaaa ctcatatgtt
    10861 agttgttcaa gcatacgagt taagcttact gtactgtatt caagtgatat atttgataaa
    10921 ttaaaccttg taatttcaaa gaattcatta attaaatctt caagacgctc tgccttatcc
    10981 aacgaaatag ataaatattt ttttcgcagt tcttcagaaa tctgactttc atctcgaagt
    11041 agtgtcagat accctataac tgatgtaagt ggtgttttta aatcatgtgc aagataaaca
    11101 ataagttcat tcttacgttg ttctgccatt tgtgtctcaa atttacgttg ttcaagtata
    11161 tgtttaattg agtttatttt cttttctatt gccaataact ctggagataa agccacttct
    11221 ccaacatctt ctttgataag agagtcaata ccttgattta tttcactaaa atattttgta
    11281 aaccaattta aataaacacg gaatattata aaaaacacaa tcaccatagc tagtatcatg
    11341 aagagctcca tgctattacg gaaaatctgc tgatataaat tcaatgcagc tttatattcc
    11401 atacgaaaag cattttcaaa aaatgatact atccagatag aaaacttacc atacaatata
    11461 aaagaatata aaatccatat gaaaataatg gctataaatg ccattaaagc tgttctcata
    11521 aaaattttat ttctcacttg agtaaagtca ggattgactt taatattttt acttttcaat
    11581 tgtataacct actccccata cagtttttat aaatttcggg tttttagaag gttcatgaat
    11641 tttttcacgt aatcgcccta tatgagccat aactgtgtta ttattatcaa gatatttttc
    11701 tccccataca gcttcaaaca attcttcaga aggaaccact tttccttgat gttcacataa
    11761 ataccaaaga atagaaaatt caatcggtgt taatgctact tctttcccaa ataaactaca
    11821 tttatgtgtt tctttattga taatcaatcc tttaatatca tactcattaa caattatcga
    11881 ctgttgttca taagaattat tatatcgcat atatcttctt aattgtgtct ttactcttgc
    11941 aacaacttcc aaagggttaa atggctttgt tatataatca tcagcaccta tggttaaacc
    12001 cattatcttg tctatatctt caattttagc tgttaacata atgataggat aatagtattt
    12061 ttctcgaatt ttctggcaaa tatgaaatcc atcaatatca ggaagcataa tatctaaaat
    12121 agccatatcc aaatttttag attcaataca ttctagagct tccttacctg tataaaactt
    12181 gtatactgta aaaccttcat tttttaaata tacttcaatt aaatctgcta tttctttttc
    12241 atcatccaca atcaaaatat tttcgttcat agattatttt tcactctcct tattatcgag
    12301 gtcatcattt ataatattgg taaatttaca tatcaaataa ttacaagcat atttgtaact
    12361 aatttttata agaaaagaac tactacatca gaatgtgttg atgctaccat tggaacacaa
    12421 aaactgagat taattgttat tataaaaact cccctaacac gtccttatta tcgcataaca
    12481 ggtattaact ttcaataaaa atatctatca gtcaaacaca attcaattta ttataccaga
    12541 gacaatccat ataaaaaata attaaaccta tgtatgtaac cacagacatt actaaaattt
    12601 ccatgttatt ttatataaaa attcaaaaaa ggagttgaat ttaaaatttg attagaaaaa
    12661 aatcaatttt gagacaactc ctttttattt taatgtattt aaattatagt atatcagcct
    12721 tcataatatc ctcaaaatca cctttttcag atattaatct tatcaattta acagtacagc
    12781 ttaaatcatt tataagtata gctccaacta atgaaccatc tttcataaat aattttttat
    12841 atattctttg accttcatct tttgatgaaa tttctttatc aaaattttgt atattaccaa
    12901 tactaaatac ttttacattc attgcatcta atgaaactgg atatacttca ctttcaaatg
    12961 tcaaattatc tccacttgca tttgcccctg ctatttttcc catttctact gaagatggcc
    13021 atattgctaa actaatattt cccacttgtg caacatctcc acaagcatat atatctttaa
    13081 tatttgtctg taatgtctta tctacaacaa tacctctatc aatttttaca gatgtatcct
    13141 gaaccatttg agtgtttgct cttacaccaa ttgaaaatac taccatatca cagtcaacac
    13201 tatctccatc tttaaataca actttttgag cttttccatc accttcaata ccatcaactg
    13261 ctacacccaa tcttacatct attcctgtat ctcttacaca ttgttctaat attttactac
    13321 cttctttatc aagttgtttt gatagtatgc tatccatggc ttcaactact actacttcta
    13381 atccttttag tctaaattcc catgcagctt caagtcccaa taaaccgcca ccaatcacta
    13441 caactttctt agatttttct agtgcttctt ttacactata taaatctttt atatttctaa
    13501 gagtaaacac attttctaaa tcatgaccct taattggtgg tataaagttt ctacttcctg
    13561 tagctattac aagcttatca aatttaatag ctccatcatt cactataata gttttattca
    13621 cttcatctaa tttatctaca ttcgttccta atattactac tatattattt ttatcatacc
    13681 aatctttatc ttccatgtag aaatctgaac caagttcttc atttatacca tcagaaagtg
    13741 caggtctata gtaagtcaac tcatcttcat tagaaatcat agttatctta caagttttat
    13801 ttctttttct tatagcatct gctgcataaa aaccagctgc tccatttcct actattacga
    13861 aatattcatc agtatctttt ctaaaagtaa cttcatcttc ttcaacttct ataaattggt
    13921 cttccttagc tccacataca gggcatacac taggagcact atcaccttca aaaacttcat
    13981 tacaaattac acatttaaat ttcttagttt tctttttact tccaaaagta gaatttaact
    14041 tatctaggaa tttacctgta taagaatgta atttatcaat ctcttcattt gatggtttaa
    14101 agttaacagc aaaaggtttt actgctgtca ttctaagctg acttattctc tccatagcat
    14161 tttctatacc ttctccactc catccatatg aaccaaatac tgaagcaact tttccaccat
    14221 gaagaactgg gtttaacgat attaatatat cccatatagg ctttaacgca tctcctaata
    14281 ttgttggtgt tccaaataat acaccttgtg atactgctat ttttgccaaa atatcttctt
    14341 gcttatgctc tattacatca aataaattta ctttatagtt gctatttttt tcaatatatg
    14401 cttttatagc ttctgccata atctttgtat atccatgtgc agaaacataa caaattgtaa
    14461 cttctttttc taactttatt tgttcattta cactccagtt gtaataaagg tctataattt
    14521 ttctaggatt ttcagttaat actggaccat gacctggaca tacagtatct atatctaaat
    14581 cttttatctt ttctatagca gttaccatag atggtttaaa tggacccatt atacaatcat
    14641 aatagtatct taaagcatcc aagtaatcct tttcttcatt ttcatcaagt gtatttacta
    14701 tcttatcatt actatagtga ctaccaaatg aatcacatgt tacaagagtt ttatcctctt
    14761 ttatatatgt gtatatggta tctggccaat gaagcatagg tacagagaaa aattctaaag
    14821 ttttgtcccc aattgataat gtatctccat ctgtaactgc aacatattca aagtctttgt
    14881 ttacgatttc cttaagatat ttaattgctg tttctgaagc tactactttt gcatttttag
    14941 ctaaatccaa aagcttttca acgcttcctg catggtctgg ttcagtatga cttacaacaa
    15001 tatagtctat tttttcaaaa tctatattta aatcatttaa tctttcaata taattgtcaa
    15061 aatgcttatc tttaactgtc tcaaataaaa ctgttttttc tgttcctttt aatacatatg
    15121 aattataagt agttccataa ggtgtataca taattatgtc aaatactctt aaatcagggt
    15181 caagcgaacc tacccaatat aaattttctt ttatttttag tgatttcaat gacataccgt
    15241 actcctccta aaatagttat ttagtctctt tataccctgc ttgttatatt ttaaacaaaa
    15301 tttattcaaa aaagaaatta ttttaaagat agtttaaatc ttctaatctt ctttttctac
    15361 cttcaataca gttccctttt tagaatctac ttttatgtca tattcatttt tatctttatc
    15421 tattcttatt ttataaaaag taacatctaa atctttgtct aaactccatt ctttaactat
    15481 tccattttgt tcttttaatg caatttccat agcttgttga ggtgtcatta tgtcatttaa
    15541 atctaatttt tcttttctag caactccatt taaatcttct gaatccaact tttctgtttt
    15601 atcttctaat acatcttttg tattagcatc aattttcatc ttatattcat tattatcatc
    15661 tacaccttcc acagtataaa caaatttatt taaatctctc tcaagactta aatctactat
    15721 atcagcatcc ttatatttat ctttaaatat gtttattgca tctgtgtatg gcactttaaa
    15781 atcttgttcc attaaatttt cattattttt ttcatctttt aaagcgttat ttgatgcatt
    15841 tgcctccttt tttgtattat cttgtgcttg tcctgaatcc ttagttggac tcccactaca
    15901 tgcagttaat aaacccgcta taagcatact taccactaat aaatacgttt ttttacacat
    15961 aaaaaccctc cttaaatata ttaatttatt ctatattatg ccctctaaac cctttattta
    16021 cccttttata ttaaaaattc ctcctatttt atcaatttta aaactttata tttactaaaa
    16081 ttaaagttac ataaaaatta tactgtctca aaatggaaac aagcctcttt ttcattgttg
    16141 aaataataaa aatatatttt atttcgtaca aaaagagtgc ctcatgaact aaaaagttca
    16201 ttttgagaca ctcccatttt tttatatttt tacttacaaa ataacagtac ttattaattt
    16261 tttacaaacc ttataagtat atctatatga tattcttaaa tttaaacact atattaaaaa
    16321 attaaatttt gtttaattct tttaccgtta aatccatttt aggatatgga atcgtaattc
    16381 cttcttcgtc aaacttaact ttaacctctt ctagtaaatc aagataaatt gtccaataat
    16441 cttctgtctt gcaccaaact ctagttgcaa atttaatagc attatctcca tgttctacta
    16501 ctcctataaa tggttctggt tcatttatta ttaatttatg attattaaca atatctttaa
    16561 gtactcttct aacatgtagt atatcatctt cataccctac actaaaagtc aaatcaactc
    16621 gtctagtatt ctttgctgaa tagtttatta gactatcatt tgatacagaa ccattaggta
    16681 taagtatctg tttattatct ggagtaacca attgtgtata aaaaagacct atttgttcaa
    16741 ccgttcctcc atgacctgct gcttctacgt aatctcctac tttaaaaggt ctaatcaata
    16801 gtataataaa tcctccagca aaatttgata gactaccttg taaagccaaa cctattgcta
    16861 cccctgctga tgctatcaca gcagcaaaac tggacaaact cattccccaa tattccagaa
    16921 caatgattat aacggcaact ttaagtacac tcaaaagaag agactttaaa aactttctta
    16981 aagttaaatc aatatctctt ttactaagta ataacataac atggtttaca aattttttta
    17041 ttattttaaa tccaatagaa agtataagta tgcctattat aagttttact ccgcttgtag
    17101 tagcccattc tagcagactt tccattatac ctcccatatc catcttatta atatctaaat
    17161 tatttaaatc taacttgctt atatcatcta ttttcgtcgt atccataaaa aactccttac
    17221 cttatatttt agaaccaata ttatagttta aagttcttat tttctattta atataataca
    17281 ataccatttg tacatagtaa acaagattta tattccaatt atacatatta ggaaaatgca
    17341 aactatttgt tatatatatg caaaatataa tactaaatta aactattaat aaaacactat
    17401 atagccttaa aatcatcatt ttttacccct atatgagatg atactatagt tataatactt
    17461 agtactataa atactacaaa acctttttta tatccatcaa ctatattata tgaatttact
    17521 tgtaaagaga tagctataat caaattaata attccacttc ctataaattc aaaagtatta
    17581 ataacactag ttgccagtcc agaataaatt tctttatttt tatacttggt atcattaaaa
    17641 acctgtagat gtgacataac tatacatccc ataataaaga atgatattgg taaaactata
    17701 attggtggtt ttacctggta tacaactaca attacaatcc atataaacaa atctatcatt
    17761 gctccaaatt ttattatatt aaatttgcta gaccttattt tagcaaatac aaaatccata
    17821 attattgaac caaatataaa tccatatgta aaaaatgata ctataaacgc agaaaaactc
    17881 ttactcacac cataaacgtc cattatgtat cttactcccc acaagcttat aaatgcactt
    17941 gtaagaccaa caaaagagaa cattatcatt gaattatacc atgttgattt gttctttata
    18001 acagacttaa taccatcaac aatattaacc ttctctgact tttcataggg ttcagtatct
    18061 acattgaatc catactcttt tggtgtatct ctaacaataa tatacataaa acatccaatt
    18121 acaacaccaa ttataccgat taataaaaat gaatttctcc aaccaacaag ttcagacaaa
    18181 aacacaagtg gaaaagtagc aagaactcca cctaaatttc ctacaaatga aaatttagct
    18241 gttgcagaag caaattctga cttattaaac catctccctt gaatttttaa aatacaaagt
    18301 aatattactg atgttcctgc ccctacaatt acacgagaaa tatatgctaa ttctatactt
    18361 tgaatcaaac caaataaaat tgaccctaaa cttgccatta ttattccaag actgctaatt
    18421 tttcttgctc catatttatc aatcaaaatt cctgcaggta tttgcataaa tgcatatgca
    18481 tataggcaaa aggatgctat atttgaaatt tgtatagaat taaaacctaa ctcatttgct
    18541 aaattgtctg aaacaacagc agttgacatc cttaaaaata atactaaaac aaatgaaaat
    18601 gtaattatac cccaaacact ccacttagcc tttgtataac ttttcatatc ttctccctca
    18661 aatccatata tttttaaatt ttcttgatat aacttatata aagtgtatag ttattcttac
    18721 aaatttttac acgcaatatc attatacaac atatgtatat atttaactag aaataaaaca
    18781 ctattcatat tatatacatg aattaactac ataaataata agagccatct tttaacatta
    18841 ctcaaaagat agctccatat aaaaacattt attctaaatt taatttttta tctaatataa
    18901 attttgtagc gaaaaataac gctattgcaa ctacaagact accaagtatt gcaagcataa
    18961 aactaggact ctgataaaga tgatatacca tatttgtatc ttcatttggt aagatgcttc
    19021 caactgcatc tccaacaatt gatattacta tatttatagc tataaaagaa gcaaatgcca
    19081 ctatgtttct atgtttattg aattttggca attgtcccat tgagattgat gtatataata
    19141 acaaaataaa tgatgaatat gaaataaaca ttactactac taataataaa atatctaaaa
    19201 agttttcaga aatccattta aaactagtgt taaacaaatc taaaatttca ggtagtaaaa
    19261 ttccagaagt accaaaaagc ataagaactc caaaagtgaa tactgcaact ataaaactaa
    19321 gtacagcgta tataagtgct gttatacatt tagataatat aagtgaacta gtgctaacag
    19381 gaagagtaaa cattaaataa ccttcatccc ccaaaagatt ttttctaaac ctttgaattg
    19441 taactacaat agttaaaact cctaatgcca taaaaagact tgttaatact agtattccta
    19501 ttccctgtac ctgaagtata tttgtattca taaatattcc attaaataca gctactatca
    19561 atatggctat atataacggt ataaatattc ttccacttgc ttttaactca tattttaata
    19621 atttacctaa catttaaatt cctccctaaa taatgcatct atagattttc ctttttcttc
    19681 tcttattgct tcaacgtctc cttgtaacac tatttctcct tttgatatga atattatctc
    19741 atcacatatg ttttctattt cacttattaa gtgggtagca atcagtaaag tactatcttc
    19801 agaataattt tttaatatag tcttaagtat atatgacctt gcagctgggt caacaccacc
    19861 tataggttca tccaatatat atatgctcgc atttcttgac attactaaaa taagttgaac
    19921 tttttcttta gttcctttag acattgtctt tagcttttca tttacatcaa tatctaagct
    19981 tttaatcatc tcatttgctc ttctaacatc aaaatcacta taaaaatcat agaaaaactt
    20041 aagtaaatct gataccttca tccaatcatt taaataagtt ctttctggta aatatgaaac
    20101 tattttttta gtatctatgg atggtttcat tccatttatc ataatttcac cattatcagg
    20161 ctgtaataat ccattcatta gcttaatcat tgtacttttg ccacttccat taggtcctaa
    20221 cagcccgact atttttccct ttggtatatt taaatcaata ttttttaaaa cattcttagt
    20281 tccataactc ttgtttacac ctttaaattc aactattcca tcttgagaaa cattgcttat
    20341 atttttatcc attttataat tctcctttca gattttctgt aataagtttt agcatttcat
    20401 ctctatcata tccaagcttt tctaaggtta cttttaatgt atttatctcc acattagcta
    20461 tttcctcttt catagctttt attttttcct tatcatctgt tacaaatctt cctttagttc
    20521 tctgactata aactaaacct tgtctttcaa gttctgttag agccttttgc attgtatttg
    20581 gattaacttc cgcatcttct gctagtgctc tcactgtttc taatttagat cctattttaa
    20641 tttcccctga aattattttt aactttaaat gttctactaa ttgtatatat ataggtttgt
    20701 tattatcaag ttcccattcc atgttcatgc ctccttatta tattattgta ttaagttgtt
    20761 aatacaataa tataataata caaagtatat gtcaattact ttttagtaaa agtataaaaa
    20821 attttacaaa aaaaatgaac actacattag agtccatttt taacacaatt tattaaattc
    20881 tttatattac agattaatta ccctcttatc aagttggata caattaaatg ttcaaattct
    20941 tcaattggca ttggctttcc aaacaaatat ccttgtgcca tatcacactt tacttctttt
    21001 aaaagtttaa actgttcttc tgtctcaact ccttctgata tgactttcat acccaactct
    21061 tttgccattt ctattacttt agtaacaatt attttgcttc ttttactatt ataagtttcc
    21121 ataataaatt tttggtcaag ttttaagata tccataggaa tttcttttaa catatttaat
    21181 gatgagtacc ctgaaccaaa atcatccata gatattaaaa atcctatttt ttttaaatta
    21241 ttcattatat caattaaaat atcaaaatta tcaaatatga tactctccgt taattcaagt
    21301 tctatatact ttgcaggtat attgtattta tcaattatat ttttgtatgt ttctataaaa
    21361 ttattgcaat ataaatgtat ccttgaaaca ttaactgaaa cagtaactgg atttattcct
    21421 gcatcaatcc attttctaag gtatatacat acttcttcaa gcacatataa atctaaattt
    21481 ataacaaaac cgtttctttc aaaaaatggg ataaattcat ttggaggtat tagcccttta
    21541 tcaggacgtt tccacctaac aagtgcttct gaaccttgta tctctcctgt attaagttct
    21601 atcttaggtt gtaagtatat aataaattct ttattttcta gacttgaaaa cattgtattt
    21661 tccatctctt tttcttttat ctcttggtca tgaatcttat tatcataaaa tgcatatgaa
    21721 cttttatgtc ctccctttgc cattttatga ggtatattag ccctatctat gattgagttg
    21781 atatctctat cttctggaag tataaaatag attccacaac ttaaaactaa cttatatttt
    21841 tcttcttgat tattattaaa caagtctaat tcttcaaata tagtttttaa cctctttgtt
    21901 atatcttctt cttctatata tttcataatt ataataaaat tatccgcaga tattcttgca
    21961 aacatttcct cttcaaatat attactctta ataatctttg ttaaattacg caaaatttca
    22021 ttcccaactt catatccaaa taaatcattt atatatttaa atttatcaat atctatatat
    22081 aataaagcat actttacttg agtattttta catagtattt tgttagcatc aattacaaat
    22141 ttatctatag tatttgctcc tgtaagatta tctgtatatg ctatcctttg caatttaatt
    22201 ttaaaattta atttatcata tattatatag aatataagta ttacacatat tatagccata
    22261 ataagtatta tttgtattgc atgtttgcta ataagctgat tattagacac aatagactca
    22321 aagttattta tggagttgtt tttatagagt ttgcataaag aatagactgg tgttgtgtat
    22381 gtaatttgta aaattataca aataaataaa aaaaacatca attttttttg taaattcctc
    22441 ataaaaattt cctcccatta aaacacctct attttattag caaataagta catctcaaaa
    22501 gtttccattt cttgtaaaat ggatagttta tatctacttt aattttgtaa aattttctgc
    22561 tactataatt atagaatgta gcatattcat tgtcttaact attgatttat atatttcata
    22621 taggtataat agaaaataaa ttggattatt ttggcatata attatttatt aaaaggtgat
    22681 tatttttgtt taaattgtct gaaaaatttt atttttatat tataatttta atattttctt
    22741 ttc
//
LOCUS       DAMJXI010000058        22352 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.060, whole genome shotgun sequence.
ACCESSION   DAMJXI010000058 DAMJXI010000000
VERSION     DAMJXI010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22352
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.060"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(137..1327)
                     /locus_tag="PC465_002810"
     CDS             complement(137..1327)
                     /locus_tag="PC465_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF2650096.1"
                     /translation="MNFNQKRIAASIMATAIIMPTMGNLAYANESEVESVSIESRTIT
                     GNAVNFRKGPGTNHESMGKLYKGDKVEYVGKEGSWVKVKYNGNTGYVHGNYVAINSLG
                     SSNESSDTSVKSTKVVTAKGLNFRTGPSTSSSKISTLGYGTEVGYISESNGWSKISSN
                     GRVGYVSSKYLGTSVNDSTNENAENSSNDLVKGTKVVTAKSLNVRTGPGTSHSKIATL
                     SYGTEVGSISESGGWTKVSYGNQTGYVSSQYLAEKGSVDTSIPSYSTNSPSQGADSVI
                     SFAKTLLGKPYVWGAEGPNSFDCSGFTQYVMKKSAGVSIPRVSRDQSKYGTYVNRGDL
                     RSGDLVFFDTQGSNNGSVSHVGIYIGNGDMIHASSGSSKKVTISNINSSYYSSRYVNA
                     RRVL"
     gene            complement(1587..2018)
                     /gene="dut"
                     /locus_tag="PC465_002811"
     CDS             complement(1587..2018)
                     /gene="dut"
                     /locus_tag="PC465_002811"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HDF2650097.1"
                     /translation="MYNLKVKKLNDDAIIPNFAHKGDAGMDLYSIEEVVIPPGETKLI
                     KTGICIELPTMTEAQVRPRSGLALKHSVTVLNTPGTIDEGYRGELKIILINHGKNDFK
                     VEKHMKIAQMIVKPIYDINIEEVKELSDSERGKGGFGSTGF"
     gene            2131..4359
                     /locus_tag="PC465_002812"
     CDS             2131..4359
                     /locus_tag="PC465_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HDF2650098.1"
                     /translation="MKLVLAEKPSVAKTIASFLGAKTRQDGYFEGNDYIITYAVGHLV
                     SLYDMKDYDKDKYSGSWKMNNFPFVPEDKFKFKIDSSKTKQFNTVKKLLNRKDVEYVI
                     NATDNDREGELIAFLIFLLAKNKKPVKRILVNEWTPEDITRGIKNLKDEDEMRNLQAA
                     GYTRLITDWLIGINFTSVATLKYGNGKLLNIGRVILPTVKLVYDRDMEILNFVPKTYY
                     EIEGHFKAEAGEYKGKYVKGKESKFDTLEDANKIIASITSETGKILDKKVTMSKEYAP
                     KLFSLTSLQGYITSKYSNFTSDKVLNVCQSLYEGNGKGGYITYPRTDSIFLEESLASK
                     ASQTLDKLKVGLEYENKIKFSKTKRVFDSSKVDSHSAIIPTYIIPKSLSKDEQLVYDA
                     IKDRFVANFMPPAEYENTEIKTEVDNCTFLTKGKVLKSKGYLEVYNKEEKNDLLPLVN
                     KDDVVDVLEIKPLTKQTTPPKPYTEDTLLKAMKNCGKNVPEEDTTVLSGYSIGTSATR
                     ADVLKKISQVGYVKKKGKSYSITDLGKNLVEIFPVKDLFDVDYTGKLEKSLSDIQKGK
                     YTRKEYLTNIISFIYQNVNIIKQDASKNINTEAYTFDSKTKKFTKTKEKKQKKDVTNT
                     EKEVAISKDSNNKKEVKNGDENQSLGKCPICQGDVLEFDKGFACKNHKECKFVIWKND
                     KYLSLYKKKVNKTMVKNILKKGETKVKSLTAKNGNKFDATLKYDKNPDTGYFNWKIEF
                     DN"
     gene            complement(4470..4955)
                     /locus_tag="PC465_002813"
     CDS             complement(4470..4955)
                     /locus_tag="PC465_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2650099.1"
                     /translation="MDNNNILKIADSFLDFLFVLENNIFKESDLLKKFQNNSDIMKAY
                     FEECPMAPSHAKVILYLMTSNSSSISQIASNLGILKSNMTPIIDRLVEHGLVNKFPDP
                     KDRRILRVELTDKAFKLFDAVKAILKESLVKKLSNLSEEELTLLDEHTLKLSEIVKKL
                     G"
     gene            5207..6430
                     /locus_tag="PC465_002814"
     CDS             5207..6430
                     /locus_tag="PC465_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HDF2650100.1"
                     /translation="MKRYLIVFLMCSSLFLVGCGKTEESEPEKPIAVSVQKAIGGEIE
                     NTNSFSGTTKVKDETAVTAQTVGTVQEVYVKLGQNVRKGDELLSISSPELENSVKQSK
                     ASLDLAKASYSSATGGSLEAQVNQAKTALDNAKIQYEESQRNYDNNKILYEQEVISLD
                     QFKKIEFSLEQTKQQLDSAQRAYDTATSKSIPQAKALAKKQLDQAQVSYNLAMSNLDK
                     LTLTSPVDGTITAKNFDSKEMITQSQPAFIISNPNILEVDLNVAESDIGKFKKDGNVD
                     VIIEDQRILGKIDYVPSVVDPQTSLYPVKVLVNNTNNKFKAGMSAQVNLSVEKENGAV
                     TVPKKAIFEENGKKYVYIATKDNIAKKHLVQTGIVTEDKIEIKSGVSDKDTVIIGGIS
                     LISDGTKIFPVEKEK"
     gene            6434..9568
                     /locus_tag="PC465_002815"
     CDS             6434..9568
                     /locus_tag="PC465_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HDF2650101.1"
                     /translation="MNLTQTSVKRPLTIIMVFLVLIVFGGIGYKKMSINLMPDIEIPV
                     VMVMTTWTGAGPQDVDEQVSQKVDESLSAVSNVKSTISSSQESVSMVVAQFEFGTNLD
                     EIMNDVRSKVDALQTSLPDDAAKPTVLKLDMNAQAIGQLVISGGNENSSQALRKYAED
                     VIQPKIESIDGVTSADLKGGEKAQVNVIADPAVLSNYGVSLSTIKGVLSSSNKTFPYG
                     AITQGEDKIVLRAIDKLESLDDIKQIQIPVKGGNTVRLDNLCSVDYGYADKDSIYRYN
                     GKDSLVIDISKQQDANTVKVMQSAYKYVDELNKENPQFKIKIANDTSSYISESINSVM
                     SNLLISAVIAFIVIFAFLKSVRASLVVAVAIPISIIGAIAILYFTGESLNLITASSLV
                     ISVGMVVDNATVVIENIFKYRKSGRLSLDDCAIEGTRTVTNAILASTLTTIAIFLPIM
                     FTEGIAKITFGALGKTLIASLAFSFIGAITLVPSVFAKLSRGKNSQKMQEKDSPIFDK
                     VSEAYKKLLSVCLRHQRLVVISSLLIFVASLFGMGFIGMDFMPAADKGELSISIELPK
                     GLSLESNDYYVSMTEKKVSDIPEIKTLITTLTSDSNNSKASIAIELESQKNRKRTTDE
                     IEKEIIDRVATVPDCKINVSQNSSVMGGAGGADFTLEMKGPDLDVLKILGKEAEKEFS
                     SIKGFRNVETSLTDTTQEAQFTIDKHKAQEYGVNTAEIAGMLRTAINGDSVTTATIDD
                     YKVDVNLKFKADTIDSLEDIKQLKVNSATGKEVPLGAFSDIKMADGLQSISRTDGDFS
                     VNITATLDNLDAGTATKLALEKTNKMVIPKDYSIGVGGETEMMNESMASLGFSMVIAI
                     ALVYMVMVAQFESFSKPFIIMFCVPFAFVGVVLSLLVSGQSLSTVGMLGIILLIGIVV
                     NNGIVLIDYIEQLRKTNRNNDLIGLVSIGCAARLRPVLMTTATTILGMLPTALSLGEG
                     GETMQPLAIVIMGGLTVSTLITLVLIPTIYLIFDKWENKFSDKMPKIFGKITDKIGSI
                     KRKIIKKPKLKAKV"
     gene            9602..10900
                     /locus_tag="PC465_002816"
     CDS             9602..10900
                     /locus_tag="PC465_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HDF2650102.1"
                     /translation="MSKIVAIGCGVGIITANLIPVYADNNTSSINKVDNSILSDSNKR
                     TSEKEILTAREAVSAALKNSEKLKMKSEEIKMLKEKLEVQDEFDSFTGSDNSFPYDQI
                     GLLKNQSEQAKGFMEDQIANDITNKFNDLVSRENELDKIKNNLEIKTKEIKDMKLKKD
                     LGLVTSLETESAELELQTLQNTQKAKLQELKNNQDYFKLLTNIDLNNYQLDKEYRFES
                     FRVGGSVDSYMEGKVNEYLKYDQLILERTEESFNDKDENKADLPDRPNLTRPVAPTKP
                     EQGNLTDDEYKVLMDKYEKDYDRYKKEVEAYNLERQTYAAGLTTYANYLQQKFNTENG
                     LVTLEDSKKALKKGLIDSYAQLLALEDTIQITKKQLDLSEKQLKNTKLRYDLGLITLT
                     DYKKQVVSNEDAKNSYDSLIVNYNSLKNGIEKPWILNSGK"
     gene            complement(11176..11421)
                     /locus_tag="PC465_002817"
     CDS             complement(11176..11421)
                     /locus_tag="PC465_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2650103.1"
                     /translation="MTKCPKCGKEVSSRPGSICPRCGFKVADESLKIRCPEPSCRALV
                     SRKLDYCPKCGCKLRGYNISEFVNMVRCKIDETFDKK"
     gene            complement(11635..14262)
                     /locus_tag="PC465_002818"
     CDS             complement(11635..14262)
                     /locus_tag="PC465_002818"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HDF2650104.1"
                     /translation="METKYVYSFGEGSKDMKSLLGGKGANLAEMTKIGLPVPPGFTIT
                     TEACNDYYVNNESIRAEIIKEIEEHLATLEKDLNKTLGCNKNPLLVSVRSGAVFSMPG
                     MMDTILNLGLNDNSVVGLAEATQNERFAYDSYRRFIQMFSDVAMEVPKYKFENVLDRV
                     KEAKGYTVDTELTTDDLKEIVKEFKAIYKKEIKNDFPQDPKEQLMLAIEAVFRSWNNP
                     RAIVYRKLNDIAHNLGTAVNIQSMVFGNMGETSGTGVAFTRNPATGENKLFGEFLMNA
                     QGEDVVAGIRTPQNISTLADVMPAVFDEFVKITHILEGHYKDMQDIEFTIENERLYIL
                     QTRNGKRTAAAAINVAVDLVEAGIIDEKEAIMRIEPNQLDQLLHPKFEDKALKEAKVI
                     AKGLPASPGAASGKVYFNADDVVKANEKGEKVVLVRLETSPEDIEGMVKAEGILTARG
                     GMTSHAAVVARGMGKCCVAGCGEIKVDEFNKEIRALDDVVIKEGEYISIDGSTGNVYL
                     GDVKKTEVSLTGNFEKLMNWVDKHKCMMVRTNADNPRDARAAIEFGAEGIGLCRTEHM
                     FFDEARLPAVREMILSNTVEQREKALEKILPMQREDFVELFKVMDGKPVNIRLLDPPL
                     HEFLPHDDETIEELSKSMGIKVSDIKKRIVDLDEFNPMLGHRGCRLAITYPEICVMQS
                     KAIIQGAIEAIKAGVKVSPEIMVPLVGEVNELKIIRKMIVETVDAIIKEEGIEVPYTV
                     GTMIEIPRACLTADEIAQEADFFSFGTNDLTQMAFGYSRDDAGKFLGQYVDEEILEKD
                     PFQVLDQNGVGKLVKMGAKLGREVKPELKLGICGEHGGEPSSVEFCYSVGLNYVSCSP
                     FRVPIARLAAAQASIKNPR"
     gene            complement(14323..15165)
                     /locus_tag="PC465_002819"
     CDS             complement(14323..15165)
                     /locus_tag="PC465_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HDF2650105.1"
                     /translation="MLVKNLIIYAVSDSVGETAQQVAKACMSQFYVNETYEIKRFPYM
                     INKGVLLETLENAKAENALIVYTLVDEELCSIVERYCEREGLSCIDLMTDILREISKR
                     TGRKPKREAGIIRKLDESYFKRVEAIEFAVKYDDGKDPRGVLQADIILVGISRTSKTP
                     LSMYLANKNIKVANVPLVPEIPIPKEVFEIDTKKIIGLTNSPEKLNEIRTQRLKALGL
                     SSKANYANLERILQELDYSEEIMKRIGCPVINVSNKAIEETAGIILDIMKENGLKIYK
                     EIEI"
     gene            complement(15172..15810)
                     /locus_tag="PC465_002820"
     CDS             complement(15172..15810)
                     /locus_tag="PC465_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2650106.1"
                     /translation="MIIIQLNERQLKIIDIVKENEPITSESIASSLNVTRATLRSDLA
                     ILTMTGILDARPKVGYFYSGVSEINLIGKSVKEKTVEDIMSMPVLAKKDESIYDVIVT
                     MFLSDVGSIVIIDENEELCGVVSRKDLLKATIGGSDINKMPIGMIMTRTPNVVTLTKG
                     ASVLLASRKIIEHEVDSIPIVEYKGEDKNHMRVVGRISKTNITKLFLEIVDN"
     gene            complement(16246..17538)
                     /locus_tag="PC465_002821"
     CDS             complement(16246..17538)
                     /locus_tag="PC465_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HDF2650107.1"
                     /translation="MLDLNRKLAKLEEEGKKIKVALIGAGHMGNGMVSQMANMKGIEA
                     SIVVDINLELAHKAFTDAGIDEEIIDNVTNEKDAEIKLQEGKVLTCNDFLVACKTKSI
                     DVVIDATGGIAIGAEIALNSILNKKHIVMLNAETDCVVGPILKKLADDAGVIFTGSAG
                     DEPGAVMELFDFADAMGFEVRVIGKGKNNKLDLDCNPDTVREEAERKGASPHMIASFK
                     EGTKTMVEMALMCNATGFVPDVRGGHGIEATVNEVPKKYALKSEGGVLDNYGVVDFVN
                     GIAPGVFVVVAHKLKAVNDELKYLSMGDGPNYILYRPYHLCSLETPLSAAMAVLDHKA
                     TIVPKAGLVAEVMTIAKKDLKKGEFMDGYGAYTCYGTIEKYDVAKAMNAVPIGLISKK
                     TKVVKDIKKGEVITYDMVEIEKDTTLYHLRQLQEKIFG"
     gene            complement(17575..17931)
                     /locus_tag="PC465_002822"
     CDS             complement(17575..17931)
                     /locus_tag="PC465_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDF2650108.1"
                     /translation="MKYEVKISGIGSLVKELMDESNCLIIYDETINDDDLKDISVIHS
                     IATLKSDVEIGDTLTIGNRDYCIVSVGDIAQKTLREIGHCTIKFDGKCEVNLPGEIHV
                     EIGNPDITIGDLITIS"
     gene            complement(17966..18325)
                     /locus_tag="PC465_002823"
     CDS             complement(17966..18325)
                     /locus_tag="PC465_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650109.1"
                     /translation="MKLLVILFVAYILNTIFIMKQNKLYFKTLNRAKKKGDIVSTGKK
                     KSYFSKGSIAVISSDSDGFIKFGEILKGRTVMAKFKEIEEIEGLDIYSAEQKFKDEES
                     IVQAIKFIKEKINVSFN"
     gene            complement(18394..20367)
                     /locus_tag="PC465_002824"
     CDS             complement(18394..20367)
                     /locus_tag="PC465_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDF2650110.1"
                     /translation="MSVTEKIPSIDRKIFKILIMCSKKEFVSINSIANELNVTTRSVR
                     TYIKQLNKDLGNDIAVIKYIKGQGYKLEIKDEQILNKIIDMNRKNVFSLNSKEDRVEF
                     ILNYLIELDGFITLDSLADEICVGRTTLVNDFQYVEKVLASYNLNLIKKQNTGMKLNG
                     NELDIRLFILNQLYKNSRKDFSNSKYFKGIKKEEIINLEEKLLTLFKKNNFYVTDEML
                     REVINYIVVLVYRVKEEKKVKDYDVKFDLLKSYDEYFIAREIKHIISGMFECTLNDEE
                     IIYLTIPLVSGNAPASECALNSSRISKNIDELMENIFNQIYVDMGIFINEDELRVGLG
                     YHLSFTLNRLLFNIKLKNVLLEEIKQNYILPFKLAQIAGKVIEKKYNLEVSEDEIGYI
                     AIHFSGYLERNSSRFYSIKKIAIICSTGLGTAKLLKIRVEKLIGNNPKIDTLSSFNLR
                     NINLDEYDIVFTTIDLDTSNINTIVLKINTIFDENKLREQLKTVLCLREGNIDTTNST
                     NLLINNLLDEDKFMILNEKTILASLEKMMDHLMDLGCIDEKFRKNIVNREEKSPTVFD
                     KGLLFPHSVNEKSDKFLMAVGILEEPIEYANRSIKIILMTMFPCENKIDSDLLVKIYE
                     EVLKIGQDVKLTNKISKCRTFLEFKKVLLKNLI"
     gene            complement(20589..21602)
                     /locus_tag="PC465_002825"
     CDS             complement(20589..21602)
                     /locus_tag="PC465_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HDF2650111.1"
                     /translation="MEENKILKIEKGTSGWGGPLYIKKEGNRNKILSMTAGGIHEVTL
                     KIKELLGCEIVDGFKTGVSDEEVAVVIIDCGGTARCGVYPKKKIPTINVNPVGKTGPL
                     AKFITEEYYVSDVNPNCISVVDGEDMPQKSQENKSENKSSIRKPDNYDEVKSKAQGEY
                     AKKNIILSIGQGAGQVVSKFYDAGRDTIQMVMNNVIPFMAFVSMLMGIILASGLGDWI
                     ARVISPLAGNIGGLLIISVICTLPFLSPILGPGAVIAQVVGTLVGTQIGLGAIPAYLA
                     LPALFAINGQAGCDFVPVGLSLGEAEPETVEYGVPALFYSRLITGPIAVIIAYGVAVF
                     ALR"
     gene            complement(21615..22160)
                     /locus_tag="PC465_002826"
     CDS             complement(21615..22160)
                     /locus_tag="PC465_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HDF2650112.1"
                     /translation="MENVITGLSKGAEWFIGLFQKGGEQFIGLVSGTLPTLIVLMVAI
                     NSLIKIIGEERVNNWASKLGKNSFTRYILLPLVSVFFLGNPMCYTFGRFLKEEHKAGF
                     YDAAVSFVHPITGLFPHANAGELFVWLGISAGLTTLGKETTTLALWYFIVGLIVIFIR
                     GIVTEKMYAFLTRKNRATNKA"
BASE COUNT         7660 a         3727 c         2890 g         8075 t
ORIGIN      
        1 agagaaaata aataaaaagc aggtatcaat aaaatagtaa catgtattat actatacatt
       61 actatcaata ttgtacctgc tttcatatta taagcaataa agaaaaatct atttattagg
      121 ttttataata aaacaattat aaaactcttc ttgcatttac atatctactt gaatagtagc
      181 tactatttat attagatatt gttacttttt ttgatgaacc tgaagatgca tgtatcatat
      241 ctccatttcc tatgtatatt ccaacatgac ttacagaacc attatttgaa ccttgtgtat
      301 caaagaatac taaatctcca cttctaaggt ctcctctatt tacatatgtt ccatacttac
      361 tttggtctct agatactctt ggtatactaa cccctgcaga ttttttcata acgtactgtg
      421 tgaatccaga acagtcaaaa ctatttggac cttctgctcc ccatacatat ggttttccaa
      481 gtagtgtctt tgcaaaactt attacactat cagctccttg acttggagaa ttagtcgaat
      541 aagatggaat tgaagtatca acagaacctt tttcagcaag gtattgactt gacacatatc
      601 cagtttgatt gccataactt acttttgtcc atcctccact ttcagaaata cttccaacct
      661 cagtaccata acttaatgta gctattttag aatgacttgt acctggtcct gttctaacgt
      721 tcaatgactt tgctgttaca acctttgtac cctttacaag gtcatttgaa ctgttttcag
      781 cattttcatt tgtagagtca tttacactag ttcctaaata tttacttgaa acataaccta
      841 ctctaccatt agaacttatt tttgaccatc catttgactc agatatgtat ccgacttcag
      901 tcccatatcc tagtgttgat attttagaac tacttgtact tggtcctgtt ctaaaattta
      961 atccttttgc tgttacaact tttgtcgact taactgaagt atcactactt tcattgctac
     1021 ttccaaggct atttattgct acataatttc catgcacata acctgtgttt ccattatatt
     1081 taacttttac ccaagaacct tcttttccta cgtactcaac tttatcacct ttgtaaagtt
     1141 tccccattga ttcatggttt gtacctggtc cttttctaaa atttaccgca ttccctgtta
     1201 ttgttctgct ttctatactc acactctcta cttcagactc attagcatat gctaaattcc
     1261 ccatagtagg cattattatc gcagtcgcca ttatactggc tgctattctc ttttgattaa
     1321 aattcataac tttccactca tctcctcttt tctactatct ttatttcact tcaaaatata
     1381 aaagaaataa ttgacactat taaaatatca attatttctt ttatattaat attattacaa
     1441 atttgtaact atttgtctat agtaacattt gcttaccata aattaccatg tataaatttt
     1501 aatctttaat agcctgtaat ttagtaatat agccatcttt tacctttttt aaaaatggct
     1561 atatttttta acttttttgt aactttttaa aatccagttg agccaaaccc accttttcct
     1621 ctttcggagt cacttaattc ttttacttct tctatgttaa tatcatagat aggttttact
     1681 atcatttgag caattttcat atgcttttca accttaaaat catttttacc atgatttatt
     1741 aatataattt taagctctcc tctgtatcct tcgtcaatag ttcctggtgt atttaataca
     1801 gtaacagaat gctttaaggc aagcccactt ctaggtctta cctgcgcttc tgtcatagta
     1861 ggaagctcta tacatatccc agttttgata agtttagtct ctccaggagg tattacaacc
     1921 tcttctatag aatacaaatc cataccagca tcacctttgt gagcaaaatt aggtattata
     1981 gcatcatcat ttaatttttt tacttttaaa ttgtacatct tatatctcct ttcaactttc
     2041 tataaatatt ataacttaaa tttcgacctc ttgaagtttt ttattttttt gtggtaatat
     2101 aattattagt gttttaaagg aggatttttt atgaaacttg tacttgccga gaaaccatct
     2161 gtggcaaaaa ctatagcatc atttttaggt gcaaagacca gacaagatgg ttactttgaa
     2221 ggaaatgatt atataattac ttatgcagtt ggacacttag tatcattata tgatatgaag
     2281 gattatgata aagataaata ctctggctct tggaaaatga acaatttccc atttgttcct
     2341 gaggataagt ttaaatttaa gattgatagt tctaaaacta aacaattcaa cactgtaaaa
     2401 aagcttttga atagaaaaga tgtagaatat gtaataaatg ccactgacaa tgaccgagaa
     2461 ggagaactta tagcattttt aatattttta ctggcaaaaa ataaaaaacc agtaaaaaga
     2521 atcttggtaa atgaatggac accagaagat attacaagag gtataaaaaa cctaaaagat
     2581 gaagatgaaa tgagaaatct tcaagctgct ggatatacta ggcttattac tgactggttg
     2641 attggaataa atttcacttc tgttgctaca ttgaaatatg gaaatgggaa actattaaac
     2701 ataggtaggg taattcttcc aacagttaaa ttagtctatg atagagatat ggaaatacta
     2761 aactttgttc ctaaaactta ttatgaaata gaagggcatt ttaaagctga agctggtgaa
     2821 tataaaggta aatatgttaa gggtaaagaa agtaaatttg atacacttga agatgcaaat
     2881 aaaattatag cttcaattac atctgaaact ggtaaaatac tagataaaaa agttactatg
     2941 tcaaaggaat atgcaccaaa actttttagt ttgacatcac ttcaaggata tataacttct
     3001 aagtattcca attttacatc tgataaggtt ttaaatgtct gtcaatctct ctatgagggt
     3061 aatggtaagg gtggatacat aacttaccct agaactgatt ccattttctt agaagaaagt
     3121 ttggcttcaa aagcttctca aactttagat aaattaaagg ttggtcttga atatgaaaat
     3181 aaaattaaat tttctaaaac taaaagagtt tttgattctt ctaaagtaga ctcccatagt
     3241 gctataattc caacttatat aattccaaaa agtttatcta aggatgaaca attagtttat
     3301 gatgccataa aagatagatt tgtagcaaat tttatgcctc ctgctgaata tgagaataca
     3361 gaaattaaga ctgaagtaga taattgtact ttcttaacaa aaggtaaggt gcttaaatca
     3421 aaaggatacc ttgaggtata taataaggaa gaaaaaaacg atttacttcc acttgtaaat
     3481 aaagatgatg ttgtagatgt gttagaaata aaaccattaa ctaagcaaac tactccacct
     3541 aaaccatata ctgaggacac ccttttaaag gctatgaaaa attgtggtaa aaatgtgcct
     3601 gaagaagata caacagtgct atctggatat tcgattggaa catcagccac acgtgctgat
     3661 gtgttaaaga agataagtca agtaggctat gtaaagaaaa aagggaaatc ttattctata
     3721 acagaccttg ggaaaaattt agttgaaatt tttcctgtta aagacttatt tgatgtagat
     3781 tatactggaa aacttgaaaa aagtttaagc gatattcaaa aaggaaagta tacaagaaaa
     3841 gaatatctta ctaatatcat tagttttata tatcaaaatg tcaatattat aaaacaagat
     3901 gcttcaaaaa atataaacac agaagcatat actttcgatt caaaaactaa aaaatttact
     3961 aaaacaaaag aaaaaaaaca gaaaaaagat gtaactaata ctgaaaaaga agttgctata
     4021 tcaaaggatt ctaataacaa aaaagaagtt aaaaatggtg atgaaaatca atctcttggc
     4081 aaatgcccca tttgtcaagg tgatgtacta gaatttgata aaggctttgc ttgtaaaaat
     4141 cataaagaat gtaaatttgt tatttggaaa aatgataagt atttaagtct ttataaaaag
     4201 aaagttaaca aaacaatggt caaaaatatt ttaaaaaaag gtgaaactaa agtaaaatct
     4261 ttaactgcta aaaacggtaa taaatttgat gctacattaa aatatgataa aaatccagat
     4321 actggctatt tcaattggaa aatagagttt gacaactaaa tattcataag aaaagaaata
     4381 gcagtagtat aataatctat attatattac tgctatttct tttcttatga agttttaact
     4441 tttttaatag tgacttttac aatcacactc taacctaatt tctttactat ttctgataac
     4501 tttaatgtat gttcatctaa taaagttagt tcctcttcag aaagattaga taattttttt
     4561 actagagatt ctttgagaat agcttttact gcatcaaata atttaaatgc tttatctgtt
     4621 aattcaaccc taagaatcct tctatctttt gggtcaggaa atttattgac taaaccatgt
     4681 tccactaatc tgtcaataat cggagtcata tttgatttta aaattcctaa attagaagct
     4741 atttgagaaa ttgatgatga atttgatgtc ataagataaa gaattacctt agcatgtgat
     4801 ggagccattg gacattcttc aaaataagct ttcattatat cagagttatt ttgaaacttt
     4861 tttaacaaat cgctttcttt aaatatatta ttttcaagca caaataaaaa atctaaaaaa
     4921 gagtccgcta ttttaagtat attgttgtta tccatatttg taacatccct tcaatagata
     4981 atataataaa acattgttgt ttaatatagt ataaattata aactattaat aaatttaaaa
     5041 caagaaaaag ttattgactc ataataatta taaatttata atcaaattag agaattataa
     5101 attgccaata aagggaagtt ttttaattag tctaaaacta aacttaaatt ataagacact
     5161 ttaaattcta caacaagcta gtgtgcaata tataatagga ggagatatga aaagatattt
     5221 aatagttttc ttaatgtgta gttcactgtt tttagttgga tgtggaaaaa cagaagaatc
     5281 tgaacctgag aaaccaatag cagtttctgt tcaaaaagca ataggtggag aaattgaaaa
     5341 cacaaattct ttctcaggaa ctacaaaggt taaagatgaa acagctgtta ctgcacagac
     5401 tgttggcaca gttcaagaag tgtatgtaaa acttgggcaa aatgtaagaa aaggagatga
     5461 attattgagt ataagcagtc cagagctaga aaatagtgta aagcaaagta aagcctcact
     5521 agatttagca aaagcaagtt attcaagtgc cactggtggt tcattagagg cacaagtaaa
     5581 tcaggcaaaa acagctcttg acaatgcaaa gattcaatat gaggagtctc aaagaaatta
     5641 tgacaataat aagattcttt atgaacagga agtcattagt ttagaccaat ttaaaaaaat
     5701 agagttttct ttagagcaaa caaaacaaca gttagattct gctcaaagag catacgatac
     5761 agcaacttca aaaagtatac ctcaagctaa agcacttgct aaaaaacagc ttgaccaagc
     5821 tcaagtatca tataatttag caatgagtaa tttagacaaa ttaacattaa catctccagt
     5881 agatggtaca ataacagcta aaaactttga ttcaaaggaa atgataacac aatcacaacc
     5941 agcttttatt atttctaatc ctaatatact agaagttgat ttaaatgtag cagaatcaga
     6001 tataggtaaa tttaagaaag atggaaatgt agatgttata attgaagacc aaaggatttt
     6061 aggaaaaata gattatgtac cttcagtagt tgaccctcag acatctttat atcctgttaa
     6121 agtacttgta aataatacaa acaacaaatt taaggcaggt atgtctgctc aagtaaactt
     6181 aagtgttgaa aaagaaaatg gtgctgttac agtacctaaa aaagcaatat ttgaagaaaa
     6241 tggtaaaaaa tatgtataca tagcaacaaa agacaatata gcaaagaaac acttggttca
     6301 aactggaatt gtaacagagg ataaaataga aattaaaagt ggtgtaagtg ataaagatac
     6361 agtgattatt ggagggataa gtcttatttc tgacggaact aagatatttc ctgtagaaaa
     6421 ggagaagtag actatgaatt taacacagac ttccgttaaa cgtcctctca caatcataat
     6481 ggtcttttta gtattaatag tttttggtgg tattggatat aaaaaaatgt caataaatct
     6541 aatgcctgat atagaaatac cagttgtaat ggtcatgact acttggacag gtgctggtcc
     6601 tcaagacgtt gatgaacaag ttagtcaaaa agttgatgaa agtttatctg ccgtttcaaa
     6661 tgtaaaatct actatatcaa gttcacaaga aagtgtttct atggtagttg ctcagtttga
     6721 atttggaact aatttggatg aaataatgaa tgatgttagg tctaaagttg atgcattaca
     6781 gaccagcctc ccagatgatg cagctaaacc aacagtttta aagctggata tgaatgcaca
     6841 ggctataggt caacttgtca tatctggagg aaatgaaaat agttcacaag ccttaagaaa
     6901 atacgctgaa gatgtaattc agcctaaaat agaatccata gatggtgtta cttcagcaga
     6961 ccttaaaggt ggagaaaaag cacaggttaa tgtaatagct gacccagctg ttctttcaaa
     7021 ttatggagtt agtttatcca ctataaaagg tgtcttatcc tctagtaata aaacattccc
     7081 ttatggtgca attactcaag gtgaggataa aatagtttta agagcgattg ataaattaga
     7141 atccctagat gatataaaac agattcaaat tcctgtaaaa ggaggaaata cagttagatt
     7201 agataatctt tgtagtgtag attatggata tgcagacaaa gatagtattt atagatacaa
     7261 tggaaaagac agtttggtaa tagatatttc taaacaacaa gatgccaaca ctgtaaaagt
     7321 tatgcagagt gcatacaaat acgtagatga attgaataag gaaaatcctc aatttaaaat
     7381 taaaattgct aatgatacaa gttcatacat aagtgaatca ataaacagtg taatgagcaa
     7441 cttgcttata agtgctgtta tcgcatttat tgtaatattt gctttcctaa aaagtgtaag
     7501 agcttcacta gttgttgcag ttgcaatacc aatttctata ataggtgcta tagcaattct
     7561 ctactttact ggtgaaagtt taaatcttat tactgcaagt tcattggtaa tttcagttgg
     7621 tatggttgtt gataatgcta cagttgtaat tgaaaatata tttaaatata ggaaaagtgg
     7681 cagattgagt cttgatgatt gtgctattga gggaacaaga actgtaacaa atgcaatact
     7741 tgcatcaaca ttgaccacaa tagcaatatt cttacctatc atgtttacag aaggtatagc
     7801 taaaataact tttggggcat taggtaaaac actaatagct tcactagcat tctcctttat
     7861 aggtgcaatt acactcgttc ctagtgtatt tgcaaaatta agcagaggaa aaaatagtca
     7921 aaagatgcaa gaaaaagata gtcctatatt tgataaggta agtgaagcat ataaaaaatt
     7981 attaagtgta tgtttgagac atcaacgctt agttgtaata tcaagtttac ttatttttgt
     8041 agcttcctta tttggaatgg gatttatagg tatggacttt atgcctgcag cagacaaggg
     8101 tgaattatct atttctatag aacttccaaa aggtcttagc ctagaatcca atgattacta
     8161 tgtatctatg actgagaaaa aagtctcaga tattccagaa attaaaactt taataacaac
     8221 tttgacatca gattcaaata atagtaaagc aagtatagca attgaattag aatctcaaaa
     8281 aaatagaaaa agaactactg atgaaataga aaaagagata attgatagag tggctactgt
     8341 accagattgt aaaataaatg taagtcaaaa cagtagtgtt atgggtggag ctggaggagc
     8401 agacttcaca ttagaaatga aaggtcctga tttagatgta ttaaaaatac tgggaaaaga
     8461 agctgaaaaa gaatttagct ctataaaagg atttagaaat gttgaaactt ctcttacaga
     8521 tacaacacaa gaagctcaat ttactataga taaacataag gctcaagaat atggtgtaaa
     8581 tactgctgaa attgcaggca tgttacgtac agcaataaat ggtgactccg taaccactgc
     8641 tactattgat gattacaaag tggatgtaaa cctaaaattt aaagcagata ctattgatag
     8701 cttagaagat ataaagcaac taaaagtaaa ctctgcaact ggaaaagaag ttcctcttgg
     8761 tgctttttca gatataaaaa tggcagatgg tctacaatct atatctagga ctgatggaga
     8821 tttttctgta aatataactg ctacacttga caatttagat gctggtactg ctacaaaact
     8881 agcactagaa aaaacgaata aaatggtaat tcctaaagat tactctatag gtgttggtgg
     8941 tgaaacagaa atgatgaatg aatctatggc aagtcttgga ttttcaatgg tcatagctat
     9001 agcattagtt tatatggtaa tggtagctca gtttgaatca tttagtaaac catttataat
     9061 catgttctgt gttccatttg cattcgttgg agttgtgctt tcgcttctag ttagtggtca
     9121 aagtttaagt actgtcggta tgctaggtat aatcttactt atcggtattg ttgttaataa
     9181 tggtatagtt cttattgact acatagagca acttagaaaa acaaatcgta acaatgattt
     9241 aattggtttg gtttcaattg gttgtgcagc aagattaaga ccagtcttaa tgactacagc
     9301 aacaacaatt ttaggtatgt tgccaacagc actatctctt ggtgaaggtg gagaaactat
     9361 gcaaccacta gccatagtta taatgggtgg tctaactgta tctacactta taactttggt
     9421 gcttatacct actatatact taatatttga taaatgggaa aataagtttt cagacaaaat
     9481 gcctaaaata tttggtaaga taacagataa aataggaagt ataaaacgta aaataataaa
     9541 gaaaccaaaa ttgaaagcta aagtttaaat agaatggagg gtgattgtat tgaataaaaa
     9601 aatgagcaaa atagttgcaa ttggctgtgg tgttggtata ataactgcca atttaatccc
     9661 agtttacgca gataataata cttcttctat aaacaaagtt gataattcta ttttaagtga
     9721 ctcaaataaa agaacatctg aaaaggaaat tttgactgct agagaagctg ttagtgctgc
     9781 acttaaaaat agtgaaaaat taaaaatgaa atcagaagaa ataaaaatgt taaaagaaaa
     9841 gttagaagta caagatgagt ttgatagttt tactggaagt gacaactcgt ttccatacga
     9901 ccaaattgga cttcttaaaa atcaaagtga acaggctaaa ggctttatgg aggaccaaat
     9961 agcaaatgat attactaata aatttaacga tttagtttca agagaaaatg agctagataa
    10021 aataaaaaac aatcttgaaa taaaaactaa agaaattaaa gatatgaaat taaaaaaaga
    10081 tttagggtta gtaacatctt tagaaactga atcagctgaa cttgaacttc aaacactaca
    10141 aaatactcaa aaagctaaac ttcaagaact aaaaaacaat caagactatt ttaagttatt
    10201 aactaatata gatttaaata attatcaatt ggataaagaa tatagatttg aatcttttag
    10261 agtaggtggc tcagttgatt catatatgga aggtaaggtt aatgaatatt taaaatacga
    10321 ccaattgatt ttagaacgta cagaagaaag ctttaatgat aaagatgaga acaaagcaga
    10381 tttaccagat agacctaacc ttacaagacc agttgctcct acaaaaccag agcaaggtaa
    10441 cctaactgat gatgaataca aggttcttat ggataagtat gaaaaagatt atgatagata
    10501 taaaaaagaa gttgaagcat acaatcttga aagacagact tatgctgctg gtcttactac
    10561 ttatgcaaat tatcttcaac aaaaatttaa tactgaaaat ggtctagtaa cattagaaga
    10621 cagtaaaaaa gctcttaaaa aagggttaat tgatagctat gctcaattac ttgctttaga
    10681 agatacaatt cagattacta aaaaacaact tgatttatca gaaaaacaat taaaaaatac
    10741 taaattaaga tatgatttag gattaattac tctaactgat tataaaaaac aagtggtaag
    10801 taatgaagat gctaaaaata gctatgactc tcttattgtg aattataact cactaaaaaa
    10861 tggtatagaa aaaccttgga tacttaattc tggtaaatag aaagattact ttaacatacg
    10921 tttgattaaa aaatagttat gcacactcgt ggctttagtc atggaagatt cagaaggcaa
    10981 ataatagaaa tagattagta aaaatatatt tacttataaa actgtatact tttatagagg
    11041 ctatctcaaa atagagataa gcctcttttt tattgtttaa attataaaaa tatatttgat
    11101 tccatacaaa aagagtgcct tatgaactaa aaagttcatt ttgagacacc ctcaaaagct
    11161 taactctaaa tttaattatt ttttatcaaa tgtctcatct attttacatc tcaccatgtt
    11221 aacaaattca gaaatattat atcctctaag tttgcatcca catttaggac aataatccag
    11281 tttcctagat accaaagccc tacaactagg ttctggacat cttattttta gactctcatc
    11341 tgctacttta aatccacatc gtgggcatat actacctgga cgtgatgata cttcctttcc
    11401 acatttagga cactttgtca actttatccc ctccagtaaa ctcaatttaa ttgatagttg
    11461 aaatttctct ctacaataat atatgcaata taattaaata cgtttcactt acaactatat
    11521 aagttaaatt tttataataa aaatccccta tattcaattt acaaatactt aatttgatac
    11581 attgaacaat aggggatttt atttttattt agttacatat tttgcagtct attattatct
    11641 aggatttttt atagatgctt gagctgctgc aagtctagca attggcactc taaatggtga
    11701 acaagataca tagttaagtc ctacactata acagaactct actgaagatg gttctcctcc
    11761 atgctctcca catattccta gttttaattc tggtttaact tctctaccta atttagctcc
    11821 catcttaact aacttaccaa caccattttg gtctagtact tggaatgggt ctttttctaa
    11881 tatttcttca tctacatatt gacctaagaa tttaccagca tcatctcttg aatatccaaa
    11941 tgccatttga gttaagtcat tagtaccaaa actgaagaag tctgcttctt gtgctatttc
    12001 atcagcagtt aaacaagctc taggtatttc tatcatagta cctacagtat aaggaacttc
    12061 tataccttct tcttttatta tagcgtcaac agtttctact atcatttttc ttattatttt
    12121 taactcattt acttctccaa ctaatggaac cattatctct ggagaaactt taacacctgc
    12181 tttgattgct tctatagcac cttgtattat agctttagat tgcattacac atatttcagg
    12241 ataagttatt gcaagtctac aacctctgtg tccaagcatt gggttaaact catctaaatc
    12301 aactattctc ttcttaatat cacttacttt tattcccata gattttgaaa gttcttctat
    12361 agtctcatca tcatgaggca aaaattcatg tagtggtgga tctagtaatc ttatattaac
    12421 tggttttcca tccataactt taaataactc tacaaaatct tctctttgca ttggtaatat
    12481 tttttcaaga gctttttctc tttgttctac tgtattagat aatatcattt ctctaactgc
    12541 tggcaatcta gcttcatcaa agaacatatg ctcagttcta catagaccta taccttctgc
    12601 accaaactct atagctgcac gagcatctct aggattatct gcattagttc taaccatcat
    12661 acatttgtgt ttgtctaccc agttcattaa tttttcaaag tttccagtca aagatacttc
    12721 tgttttctta acatctccta ggtacacatt tcctgtagaa ccatctatag aaatgtattc
    12781 tccttctttt ataactacat catcaagtgc tcttatttct ttattaaact catcaacttt
    12841 tatttctcca catccagcaa cacaacattt acccatacct ctagcaacaa ctgctgcatg
    12901 tgatgtcatt ccacctctag ctgtaaggat tccttctgct ttaaccattc cttctatatc
    12961 ttctggagat gtctctagtc taactaaaac tactttttct cctttttcat ttgcttttac
    13021 tacatcatca gcattgaaat aaactttacc acttgctgca cctggtgatg ctggtaaacc
    13081 ttttgctata accttagctt cttttaatgc cttatcttca aattttggat gtaataattg
    13141 gtctaattga ttaggctcaa ttctcatgat agcttctttt tcatcaatta ttccagcttc
    13201 aactaaatca accgctacat ttattgctgc tgctgctgtt ctcttaccat ttctagtttg
    13261 tagtatatat aatctttcat tttctatagt aaactctata tcttgcatat ctttataatg
    13321 accttcaagt atatgagtaa tttttacaaa ttcatcgaat acagctggca ttacatctgc
    13381 aagagttgat atattttgag gagttcttat acctgcaaca acgtcttcac cttgtgcatt
    13441 cattaaaaat tcaccaaata atttattttc tcctgtagct ggatttctag taaatgcaac
    13501 acctgtacca ctagtttctc ccatattacc aaataccatt gattgaatat ttactgctgt
    13561 tcctaagtta tgagctatat cattcaattt acggtatacg attgcacgag gattattcca
    13621 tgatctaaat acagcctcta ttgcaagcat taattgctct tttgggtctt gtgggaaatc
    13681 attttttatt tcttttttat aaattgcttt aaattctttt actatttctt ttaaatcatc
    13741 agttgtaagt tctgtatcaa ctgtgtatcc ctttgcttct tttactctgt ctaatacatt
    13801 ttcaaattta tattttggaa cttccatagc aacatcagaa aacatttgta tgaatcttct
    13861 gtaactatca tatgcaaatc tttcattttg tgtagcctct gctaagccaa caacactatt
    13921 gtcattaaga cctaggttaa gaattgtatc catcattcct ggcatagaga atactgcacc
    13981 agaacgaact gatactaata atggattctt attgcatcct aatgttttat ttaagtcttt
    14041 ttctaaagta gctaaatgct cttctatttc ttttattatc tctgctctta tactttcatt
    14101 gttaacataa taatcattac atgcttctgt tgttatagtg aatccaggag ggacaggtaa
    14161 gcctatctta gtcatttctg ctaaattggc acctttacct cctagtaaag atttcatgtc
    14221 tttgcttcct tcaccaaaac tataaacata cttagtttcc attgttaaat cccccattaa
    14281 tctttttatt ttaatttata tcatttttat taatagacat tattaaattt ctatttcttt
    14341 gtatatcttt agaccatttt ctttcattat gtctaaaatt atacctgctg tttcttctat
    14401 tgccttattt gaaacgttta ttactgggca tccaattctt ttcattatct cttctgaata
    14461 atctaactcc tgaagtattc tttctaaatt agcgtagttt gctttactgg acaatcctaa
    14521 agcttttaat ctttgggttc ttatctcatt cagcttttca ggtgaattag taagacctat
    14581 tatcttttta gtatctatct caaacacttc tttaggaatt ggtatttctg gaactaatgg
    14641 aacattagct acttttatat ttttattagc taaatacata ctcaaaggag ttttagatgt
    14701 tcttgatatt cccactaaaa ttatgtctgc ttgaagaaca cctctagggt cttttccatc
    14761 atcatatttc actgcaaatt ctatagcttc aactctctta aagtaagatt catctaattt
    14821 tctaattata ccagcttctc ttttaggttt tcttcctgtt ctcttgctta tttctcttag
    14881 tatatctgtc attaaatcta tacaactaag accttctctt tcgcaatatc tttcaacaat
    14941 actgcataat tcttcatcaa ctaatgtata tacaattaaa gcgttttcag cttttgcatt
    15001 ctccaaagtt tcaagtagta ctcctttatt aatcatgtat ggaaatcttt ttatttcata
    15061 agtttcattc acataaaact gagacataca tgcctttgca acttgttgtg cagtctcccc
    15121 tactgaatct gatactgcat atataattag gtttttcacc agcatacctc cttaattgtc
    15181 aactatttct aagaatagct tagttatgtt ggtttttgat attctcccaa caactctcat
    15241 atgatttttg tcttctccct tatattcaac aatcggaatc gaatctactt catgttctat
    15301 tatttttctt gaagctaata aaacacttgc tcctttagtt aaagtgacta catttggagt
    15361 tcttgtcatt atcataccta ttggcatttt atttatatca gaacctccta tagttgcttt
    15421 tagcaagtct tttctggaaa caactccaca taactcttca ttctcatcta taataactat
    15481 actccctaca tcagataaaa acatagtgac tattacatca tatatacttt catccttctt
    15541 agctagtaca ggcatgctca ttatatcctc tactgttttt tcttttacac ttttaccaat
    15601 taaatttatt tcactaactc ctgaataaaa atatccaact tttggtcttg cgtctaatat
    15661 tcctgtcatt gttaatatag ctaaatcaga tctaagtgta gcacgagtca cattcaagct
    15721 ggaggcaata ctttcactcg ttattggttc attttcctta actatatcta taatttttag
    15781 ttgtctttca ttaagctgaa taataatcac cttctttcat tgtgctatac tttttatctt
    15841 ttcgcatctt atatagtata ttatataact atatatacca ttctgtaaac agatttttta
    15901 ttgaatacga tatatttttt actaagttct ctcgcttaaa gatatttatt atatattaat
    15961 gggggatatt tctttaatta atagaactat attagtatta cagttaatat tataatacat
    16021 aattggtcat tttaattcat tttatattaa aatttttaat aatattattt caatgtgaat
    16081 ataaaattgc agaactaatt caaaataatt tttacgacta caaataacct ataatatact
    16141 tttaaagaaa gtatcctaac aagaatatat aaaaatttaa aagggttgat ttaaaaataa
    16201 ccatcaaccc tttttactaa tatctattta tattaccatc aaatcttacc caaatatttt
    16261 ttcttgcaat tgtcttaaat gatataaagt agtatctttt tctatctcta ccatatcgta
    16321 agttataact tcaccttttt taatatcttt tacaacttta gtctttttac ttatcaaacc
    16381 aataggtaca gcattcatag cctttgctac atcgtatttt tctatagtac catagcatgt
    16441 atatgctcca tagccatcca taaactcacc ttttttcaaa tctttcttag ctatagtcat
    16501 aacttctgct actagtccag ctttaggtac tattgtagcc ttatggtcta aaactgccat
    16561 agctgctgat aaaggagtct ctaaactaca taaatgatat ggtctatata atatgtaatt
    16621 aggtccatca cccatactta aatattttag ttcatcatta actgctttta atttatgggc
    16681 tactactacg aaaactccag gtgctatacc atttacaaaa tcaactacac cgtaattatc
    16741 taatactcca ccttcgcttt ttaatgcata tttcttaggt acttcattaa ctgtagcttc
    16801 aataccatga ccacctctta catcaggcac aaatccagtt gcattacaca ttaaagccat
    16861 ttctaccatt gttttagttc cttctttaaa agaagctatc atatgaggtg aagctccttt
    16921 tctttctgct tcttctctaa ctgtatcagg attacaatct aaatctaatt tattattttt
    16981 acctttacct atcactctaa cttcaaaccc cattgcatct gcaaaatcaa ataattccat
    17041 tactgcacct ggctcatctc ctgcagaacc tgtaaatatt actccagcat catctgctaa
    17101 ttttttaagt attggtccaa caacacaatc agtttcagca tttaacataa ctatatgttt
    17161 tttatttaaa atagagttta atgctatctc tgcaccaatt gcaatacccc cagttgcatc
    17221 tataactaca tctattgact tagttttaca agccacaaga aagtcattac atgtcaatac
    17281 ttttccttct tgtaatttta tttctgcatc cttttcattt gttacattat ctataatttc
    17341 ttcatctatt cctgcatcag taaaagcttt atgagccaac tccaaattta tatctacaac
    17401 aatagaagct tcaatacctt tcatatttgc catttggctt accattccat ttcccatatg
    17461 cccagctcct ataagagcta cttttatttt tttaccttcc tcttccaatt ttgcaagttt
    17521 tctgtttaaa tctaacatac caattcctcc tgttataata attttatttt caaattaaga
    17581 aatagttatt aaatctccaa tagttatatc tggatttcct atttccacat gtatttctcc
    17641 tggtaaattt acttcacatt ttccatcaaa tttgattgta caatgcccaa tttctctaag
    17701 agtcttctga gcaatatcac caactgaaac tatacaataa tctctattcc ctatagtaag
    17761 tgtatctcct atttcaacat cactttttaa cgttgctatt gaatgaatta cagatatatc
    17821 ctttaagtcg tcatcattaa tggtttcatc atatataata agacaattgc tttcatccat
    17881 taactcttta actaaactgc ctatcccact tatcttaact tcatatttca tgacattcct
    17941 cctgataatt tatatttata ttgagttaat taaaagaaac atttattttt tcttttataa
    18001 attttatagc ttgtacaata ctctcttcat ctttaaattt ttgctctgca ctatatatat
    18061 ctaatccttc tatttcttca atctctttaa atttagccat tactgtacgc ccttttaaaa
    18121 tttctccaaa ctttataaac ccatctgaat ctgaagatat aacggctata cttcctttag
    18181 aaaaatagct tttctttttg cctgtagaca ctatatcacc ctttttttta gctctattta
    18241 aagttttaaa atacaattta ttctgcttca ttataaatat agtatttaaa atataagcaa
    18301 caaataaaat tactaataat ttcatattta tacaccttcc aaaaatcaca ttatttttaa
    18361 atctgtataa caactataaa tgctgtacaa tagttatata aggtttttaa gtaacacctt
    18421 tttaaattct aaaaaagttc tacatttact tatcttattc gttaatttta catcttggcc
    18481 tatctttaaa acttcttcat aaatttttac taataagtct gagtctatct tattctcaca
    18541 tggaaacatt gtcataagaa ttatttttat acttctattt gcatattcta ttggttcttc
    18601 taaaattcca actgccatta aaaacttatc tgatttttca tttacagaat gaggaaataa
    18661 taaaccttta tcaaatactg tgggagattt ttcttctcta ttgactatat tttttctaaa
    18721 cttctcatca atacatccca aatccataag atggtccatc attttttcta atgaggcaag
    18781 tatagtcttt tcatttaata tcataaattt atcttcatct aacaaattat tgattagtaa
    18841 atttgtagaa ttagtagtgt caatattccc ttctcttagg cacaatactg tttttaattg
    18901 ttctcttagt ttgttttcat caaatattgt atttattttt aatactattg tatttatatt
    18961 tgatgtgtct aaatcaatag ttgtaaaaac tatatcgtat tcatctaagt taatatttct
    19021 caaattaaaa cttgaaagag tatcaatttt aggattattt cctatcagtt tttctactct
    19081 tattttcaat agttttgctg ttcctagacc tgtactacat ataattgcta ttttttttat
    19141 tgaatagaat ctactgctat ttctttctaa atatccactg aaatggattg ctatatatcc
    19201 aatctcatct tctgaaactt ctaagttata ctttttctct attacttttc ctgctatttg
    19261 tgctaattta aatggaagta tataattttg cttaatctct tctaacaaaa cattttttaa
    19321 ctttatatta aataatagcc tgtttaaagt aaaactaaga tgatatccta gacctactct
    19381 taattcatcc tcatttataa aaatacccat atcgacatat atttgattaa atatattttc
    19441 catcaactca tcaatgtttt tactaattct actactattt aaagcacatt ctgatgctgg
    19501 tgcatttcca ctaactaacg gtatagttaa ataaataatt tcttcatcat ttaaagtaca
    19561 ttcaaacatt cctgatatta tatgttttat ttccctagca ataaagtatt catcatatga
    19621 tttaagtaaa tcaaacttta catcataatc ttttactttc ttttcttctt ttactctata
    19681 gactaaaact actatgtagt taataacttc tcttaacatt tcatctgtaa cataaaaatt
    19741 atttttttta aataaagtca atagtttttc ttctaaattt atgatttctt cttttttgat
    19801 tcctttaaaa tactttgaat tactgaaatc ttttcttgag tttttataca actgatttaa
    19861 tataaacagt ctaatatcaa gttcatttcc atttaatttc atacctgtat tctgtttttt
    19921 aatcaagttt aaattatatg aagccaaaac tttttctaca tactggaaat catttactaa
    19981 agtagttctt cctacacata tctcatcagc taaactatca agtgtaataa atccatctag
    20041 ttctatcaag taatttagta taaactctac tctatcttct tttgaattta atgaaaatac
    20101 attttttcta ttcatatcaa taatcttatt gagtatctgc tcatctttta tttctagttt
    20161 atagccttga ccctttatat atttgattac tgctatatca ttacctaaat ctttattcaa
    20221 ttgttttata tacgtcctta cacttctagt tgtgacattc aattcatttg ctattgagtt
    20281 aatactcaca aactcttttt tactacacat aatcaatatc ttaaatatct tgcggtcaat
    20341 agaaggaatt ttctcagtta cactcatttt gtatctcctc cttgatttca ttctagtaca
    20401 aatttgaaac caaattaata cataaaattt cactttaata aaggaaaatt tagtattaat
    20461 ctaactcgat aattacagct aattaatagt ataaaagcta gtctttcatt aacaaaaaat
    20521 cttgactagc ttaaatttat atttacaatt ttattaatta attccaagcc ttatattgac
    20581 attaaatatt atctcaatgc aaatactgca actccatatg caataataac agctattgga
    20641 ccagttatta aacgagagta aaataaagct ggaacaccat actctacagt ttctggttct
    20701 gcttctccca aacttaatcc tactggtaca aaatcacatc cagcttgccc atttattgca
    20761 aataaagctg gaagtgctaa atatgctggt attgcaccaa gaccaatttg tgtacctaca
    20821 agagtcccta ctacttgagc tataactgca ccaggtccta gtattggtga taagaatgga
    20881 agtgtgcaaa ttactgatat aatcaataat ccaccaatat tacctgcaag tggagatata
    20941 actcttgcaa tccagtctcc cagtccagat gctaaaataa ttcccataag catacttaca
    21001 aatgccataa atggtattac gttattcatt accatttgga tagtatctcg acctgcatca
    21061 taaaattttg atactacttg ccctgcccct tgaccaatag aaagtattat gttcttttta
    21121 gcatattcac cttgtgcttt tgacttaacc tcatcataat tatcaggctt tctaatagaa
    21181 ctcttatttt cgcttttatt ttcttgagat ttttgtggca tatcttcccc atctacaaca
    21241 cttatacagt taggattaac atctgataca taatattctt ctgttataaa ttttgctaaa
    21301 ggacctgttt ttccaactgg atttacattt attgtaggta tttttttctt tggataaact
    21361 ccacatctag cagttccacc acaatcaata ataactactg ctacttcttc atcagaaact
    21421 ccagttttaa atccatctac aatttcacaa cccagtagtt cttttatttt taatgttact
    21481 tcatggatac caccagcagt cattgatagt atcttatttc tattcccttc tttttttata
    21541 tacaaaggac ctccccagcc tgaagttccc ttttctattt ttaatatttt attctcctcc
    21601 attttatcta cctcctaagc cttatttgtt gctctatttt ttcttgttag aaaagcatac
    21661 attttttctg ttactatacc tcttataaaa attacaatta gaccaactat aaaataccac
    21721 aatgccaatg tagtagtttc tttacctaaa gtagtcaaac ctgcagatat tcccaaccat
    21781 acaaaaagtt ctcctgcatt tgcatgtgga aaaagacctg taattggatg tacaaatgaa
    21841 actgctgcat cataaaatcc tgctttgtgc tcttctttta aaaatctacc aaatgtatag
    21901 cacataggat ttcccaagaa aaatactgat actaatggaa gtagaatata tcttgtaaaa
    21961 gagttctttc ctagcttaga agcccaatta ttaactcttt cctcaccaat tatcttaatc
    22021 aaagagttaa tagctaccat taatacaatt agcgttggaa gagtacctga aacaagacct
    22081 ataaattgtt ctcccccttt ctgaaacaaa ccgataaacc actctgcacc tttacttaga
    22141 cctgtaataa cgttttccat aaaattataa cctccctata atatctttaa atttttaatt
    22201 ttactgctta ccataaattt tacaaattac atcttttttc tgtactatat gctaatattg
    22261 taaatgtttt tttattaata tcattttaat ataatatttt tgataaataa atacatcttt
    22321 tttcaatttt ataaaggaaa aaattgtact aa
//
LOCUS       DAMJXI010000059        22145 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.061, whole genome shotgun sequence.
ACCESSION   DAMJXI010000059 DAMJXI010000000
VERSION     DAMJXI010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22145
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.061"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(200..400)
                     /locus_tag="PC465_002827"
     CDS             complement(200..400)
                     /locus_tag="PC465_002827"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650113.1"
                     /translation="MSERNSYSKTDNDATFMRMKEDHMKNGQLKPAYNIQFGVDSEYI
                     VLVSSGHQPTDTITLIPFLKSI"
     gene            complement(1095..2402)
                     /locus_tag="PC465_002828"
     CDS             complement(1095..2402)
                     /locus_tag="PC465_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2650114.1"
                     /translation="MEKGIKLGFWSIVLLGINAIIGSGIFGLPGDAYTDIGPASILVL
                     VFCMLLAVSIALCFAEAGSWFDTDGGPYLYAKEAFGDFVGFMKWIVSMIAWATMANFF
                     AVTLSSVWPQAAEPLTKNIIIGILVVGLGIINFMGMKQSKHLNNIMTIGKLLPIVLFI
                     AVGLFFIKGSNFTPFVIIQKGQSASSAFVAVSITLFYAFTGFESLAVAAKDMENPKKN
                     VPKALVMVMFVVSVIYMLILGISIGVLGNGLAGSATPVADAAIKMLGPIGGYIITIGT
                     IVSVGGINIASSIFTPRSAAALVEQGLMPKSIRKTNKNGAPYIAIIVSVIGTLLIAWS
                     GSFTTLSQISVVSRFIQYIPTCLAVLILRKKYAGKDVNFRIPGGAIIPIFAVIISILL
                     LIKAGIDEPMKIVWGLGGMIIVVPIYFYMTKVYSKKYNDVEVK"
     gene            complement(2443..3189)
                     /locus_tag="PC465_002829"
     CDS             complement(2443..3189)
                     /locus_tag="PC465_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HDF2650115.1"
                     /translation="MKKLAKKKYPIIGISGNLLIDEGGMFPGYERAYVNNDYIQSVVM
                     CKAIPYIVPIVYDDEIIKEQVSNIDALILSGGQDVNPLIWKEEPHNKLGAISPKRDSF
                     DMKLLKHALDMKKPVLGICRGEQIINVTEGGSLYQDLSLIEGAYIKHNQQHLSNVPTH
                     TVQIKEGTKLYEILGEKEVLVNSFHHLVVNKVAPGYIVSATSKDGLIEAIEKEGSEFV
                     IGIQWHPEMMTRDYDNMKKIFMAIVKEASK"
     gene            complement(3433..5442)
                     /locus_tag="PC465_002830"
     CDS             complement(3433..5442)
                     /locus_tag="PC465_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2650116.1"
                     /translation="MKTIAVVTDGLSKLECFLNKNLEMIFKDKVMIKNYYLNKITEKE
                     LIKDDIILVMIDDRVLKIKKYVEDVSKIITINRSIKQKDIYKLFSLPEGIDVLVVNDN
                     KHTVLETISNLYNIGINHLNFIPYNPNEEYRNIKIAITPGEASLVPKYIEEVIDLGHR
                     YIDSSTFIQIIAKLKLDDKEITERLIKYTDEIISLYSGINTKYKELTIKADELNSIIN
                     LSNLGMAMVSDKGNIIICNNSLGDILDIQSNIIGKNIDELENENIKKIFSLSKAHDEV
                     IKFNNKYLNVNKYNIESFGRVTGYYFCIQEITYIRKLEQNLSKKLREKGQVARYTFDD
                     IKTVSTKMERTKKLGMKIAESDYTILITGESGTGKELMAQSIHNASPRHSQPFIAINC
                     AAMPENLLESELFGYEEGAFTGALKGGKKGLFEQANNGTIFLDEIGDMPIYLQSKLLR
                     VLQENQVMRVGGENVIDIDVRVIAATNKNLLEMIKGDRFRADLYYRINVLPINIPPLR
                     ERKEDIEAMLKHFMKRKRAISQDVQDIINAYEWPGNIRELKNTAMYINIMSSEDVILI
                     NDLPHNLLNITEDFSKEISILKDRTSIEKVKLVMECLKNANNLNKNIGRNGIVNSINE
                     LGYNITEGEVRGILNMLKELDLIICESGRKGSELNRRGKNILNSI"
     gene            complement(5880..7313)
                     /locus_tag="PC465_002831"
     CDS             complement(5880..7313)
                     /locus_tag="PC465_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF2650117.1"
                     /translation="MSFKKDFLWGGATAANQCEGAWNLDGKGPSCSDMCTGGSQKVSK
                     RITRVIEKGTFYPSHEAIDFYHRYKEDIALFAEMGFKVFRFSIAWTRIFPTGMEKEPN
                     EAGLKFYENVIDECLKYNIEPLITISHYEIPFAITEKYNGWVSRDVIDLYMNYCETIF
                     KRYKGKVKYWLTFNEINSATMPMGGYLSQGILNEGTTDFINQVDILQLRFQGLHHQFV
                     ASAKAVKLAHEIDSNYQVGCMQIFATMYPYTCNPDDAVKTQRDSRVMNYFCGDVQVRG
                     EYPTYMNRYFGENNIEIKMEKGDLEILKEGCVDFYTFSYYMSTCVSSDSKEDNTSGNI
                     LGGVKNPYLKSSEWGWQIDPEGLRYALNEIYDRYRIPMMVVENGLGAYDKKESNGVIN
                     DDYRIEYLKAHIEQMKEAVEDGVDLFGYTPWGCIDLVSASTGEMAKRYGFIYVDKYDD
                     GSGDLSRIKKKSFDWYKQVIESNGERL"
     gene            complement(7329..8753)
                     /gene="ascB"
                     /locus_tag="PC465_002832"
     CDS             complement(7329..8753)
                     /gene="ascB"
                     /locus_tag="PC465_002832"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDF2650118.1"
                     /translation="MALRKDFLWGGATAANQCEGGYKEDGRGLANVDVTPQGKDRFPV
                     LAGKMKMFECDDEHYYPAHEAIDMYHNYKEDIKLFAEMGFKCYRMSIAWTRIFPTGVE
                     DVPNEEGLKFYEDLFDECLKYGIEPVVTICHFDVPMYLVKKYGAWRNRKLVDLYVKYC
                     EVIFTRFKGKVKYWLTFNEINMILHLPFIGAGLYIEEGENEEQIKYQAAHHQLVASAL
                     VTKLAHNINQEFKIGCMLAAGNTYPNTCNPLDVWKSIEKDRENYFFIDVQSRGEYPTY
                     ALKELERKGINIVMEEDDKKILKENTVDFISFSYYSSRLTSADPKVNILTEGNVFASL
                     KNPYLDASEWGWQIDPLGLRITMNSLYNRYQKPLFIVENGLGAVDNPDENGNINDDYR
                     IDYLRAHIKAMIDAVELDGVDLWGYTPWGCIDLVSASTGEMKKRYGFIYVDKDNDGNG
                     TLKRSKKKSFAWYKKVIESNGEEL"
     gene            complement(8840..10756)
                     /locus_tag="PC465_002833"
     CDS             complement(8840..10756)
                     /locus_tag="PC465_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2650119.1"
                     /translation="MRKYEQLSKEIIANVGGKDNISSLSHCITRLRFKLKDESIANDD
                     VLKKMDGIVTVMKSAGQYQVVIGNHVPDVYEVVCDLAGLGGDTIDNSDSDAPKGLLNK
                     FIDIISGVFQPILGVLCAAGMIKGFNAVFTALGLYGETDGAYIMLNAIGDAMFQYMPI
                     ILGYTAAKKFKLKPFIGMLIGAVLCYSGIQLDTLASTGQPLYNLFTGTIFESPVYITF
                     LGLPVIAMNYTSTVVPVILIVLLAAKLEKVFAKIIPDVVKNFFVPMAVLLVSLPLGFM
                     VIGPIATYASNIVGNGFLALFNFSPILCGALTGLLWQVLVIFGLHWGLVPIAMSNLMT
                     MGFDTILVGAFVPSFAQTAVVAAMYFKLKDKKIKELCIPAVISGICGVTEPAIYGITL
                     PRKTPFIYSCVGGGVAGAVMGIMNVKSYVMGGLGIFGIPNYINPTTGDMKGVYATIIA
                     IIVAIVVGFVLTLFFWKDDAIVEISKDDNGQGVIEKNKREVVYSPIKGEVKALEQIQD
                     AAFSTGILGKGVAITPKEGKVVAPFDGTVMTLFPTKHAIGIISDNGCELLIHIGLNTI
                     QLEGKYFKSFVNQGDKIKKGQTLITFDIESISKEGYCLETPVVVTNYSDYVDIVENTQ
                     KHVNNSQKLITVLA"
     gene            complement(10830..11690)
                     /locus_tag="PC465_002834"
     CDS             complement(10830..11690)
                     /locus_tag="PC465_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2650120.1"
                     /translation="MIIEKILNNNVIITTDENHKEIVVMGRGLAYKKRTGEHISKDKI
                     DKIFKLSDPNISDKFKELIADIPIRYMELSDEIILYAKEKLGKRLNDSIYISLTDHMY
                     TAIERAREGVSVKNVLLWDIKRFYKSEFKIGLEALDYIEKKFEIRLSEDEAGFIALHI
                     VNAQMDQSIKTIYEITQIIQEISNMVKYHYRIVFDEDSVYYHRFITHLKYFAERIVSN
                     NLHENNEDDLLNVIKVKYKNAYKFIEKLDEFIHKKYNYDLTDEEKLYLTIHVERVVSK
                     SIKSDINPNN"
     gene            complement(12041..13228)
                     /locus_tag="PC465_002835"
     CDS             complement(12041..13228)
                     /locus_tag="PC465_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2650121.1"
                     /translation="MIESIKKRAYEIENELGKEIEEVCNFIFNNPELGEEEYISSKYL
                     VEKMKEYGFDTVYPYCNMETAFRAELGDNDGPTIAFLAEYDALPGYGENKEPAHACGH
                     NWIAASTLGACIVLSKLKENFKGKIVLIGTPAEETTGGKCDLVKAGAFDDVDVSYQMH
                     IEAFNNINCKALAIDSLEFSFEGVSAHAASHPHMGVNALDAVQLTFAGINALRQHVKS
                     DVRIHGIVSNGGEAPNIVPEKAACKFFVRAAERSYLDEVTKKVINCAKGAELMTGAKL
                     SYRYFENSFDNIINNKVLQKITKNNLIEAGITDILEGKDGPVGSTDIGNVSQVCPTMY
                     TEIALDISPMVYVHEKEFLNYANSEEAYDKLHKAVKAMVGCALEIYLEDGLLDEIKKN
                     HLN"
     gene            complement(13242..14633)
                     /locus_tag="PC465_002836"
     CDS             complement(13242..14633)
                     /locus_tag="PC465_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HDF2650122.1"
                     /translation="MSSLKKKKFTMPQTLTIIFLLIVLMAILTWIVPSGNFERVDIDG
                     RSVVVAGTYEKAPSNPQGITDVFTAPINGFIDAAEVVGFVLIVGGAFGIVNKTGAIEA
                     VIAHTVNKMKKFQFLIIPISMILFGLGGTTFGMSEETLPFYMIFIPLMTSMGYDSLTA
                     VATVFIGATAGFGAATTNPFSVGIAQALSQIVPGSGIEFRVVMFIIYMAISIGFVMMY
                     ANKVKKDPKKSLVHDISLNQELMVNSDTNIKEFTKREAMVIAIFTIGMAIMIYGVLRL
                     EWYITEIAMIFTAIGIISGIASGLKQDEIVNSFISGAGDLITAGLCIAFARGIVIIAE
                     NGFIIDTILNSAANLLNGLPKTIFINLTFLIEGLIAFLIPSASGLASLTIPVLAPLGD
                     LVDVSRQMIVTAYQFGIGVTNLITPTSGVLMGALAVANIPWSKWVRFVIPLMVVLTIL
                     VMAFLTIGLYLGF"
     gene            complement(15228..16928)
                     /locus_tag="PC465_002837"
     CDS             complement(15228..16928)
                     /locus_tag="PC465_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2650123.1"
                     /translation="MHYIAWHFNKNGGNNTMKDKLQVLSGAMMIPVILLVVAGVFIGL
                     GSAFANMENVSALGLSGLIKEGSFINVFFKVINDLGFMVMRYLPIFFVTGIAFGLSKK
                     EKGWGALGGIVLFIGMHTVISTLLAANGINSDTVTAEAFMASGLGEAEAYSRSSLYGS
                     FLGIFSYDCSIFGAIIAGFVASAVHNKFVDIELPSALSFFSGPRFSMIMMFIASIVLG
                     TAMYLIWPPVGLALSKLGNWIGSSGLLGTFTFGAMDKALLPFGIHHLIAFPIEYTRVG
                     GTMEVGGAIYEGVNNIRLAQMGDPDTLSYITRNFTTGRLLIHFAILPAAALAMYKLAD
                     NANKKKAISILIPAIVTAMLVGVTEPIEYTFLFVAPLLYFVAYVPLAGLTYVFTEMFN
                     VSIMGESFRNMFPNLLQPQKVDALPLLFLIPIFFIVTYIIFTWAIKKFDIKTPGRSSE
                     EVKLYSKKEYRERQSVDAGKTAYNNAVEEEVDDKDTKLVHSIIEGLGGSNNIKNVTNC
                     ATRLRVELNSIDGFYEDGFWVNELGASGVVKKKNSVQVIFGPRVITIASKLKAVLGVD
                     "
     gene            complement(16900..18303)
                     /locus_tag="PC465_002838"
     CDS             complement(16900..18303)
                     /locus_tag="PC465_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2650124.1"
                     /translation="MIVNKELIIDYLKSNQENIINDIRSLVEIPSIRDESTTDINQPF
                     GIEIRNAFDKLIQIAKDKDFVVKDFDGYAIHIEYGEGEEVVGVLNHIDVVPIYNKELW
                     KSKPFKVCQKDNYLYGRGVNDNKGPLIGILYALLFLRELNEKPKRKIRLIVGGAEETT
                     WECMEHYFSVNEQPKFAFSPDGNFPIVNGEKGILYFNLRKKIDKDKFRNHNLVDIKSN
                     KEDGFVCDKIEAVFKTNDKKDLVESLAYYTEIEELEEGKVLVRYTGERALSRNPHRSY
                     NCAFSLAKDLEKIKKLNDKGVIIRDILNSYFTDDNHGKKLGIYKEDVDMGVSTICIMS
                     IFLEKNELNMKIDFRYPKGISWEFITNRINEIGKKENLIVDIYKDLKLLYVKPDSELI
                     NKLSSAYKQGFGKEAELFTKGAASYARVLKNGVAFGPTIEGDNPNSHQANENISIDTL
                     YKAIEVYIYALYSLAFQ"
     gene            complement(18567..19058)
                     /locus_tag="PC465_002839"
     CDS             complement(18567..19058)
                     /locus_tag="PC465_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2650125.1"
                     /translation="MFNIFKKKENKIEKIYSPFKGNLVNLEDVPDAVFAQKMMGDGVA
                     IIPSEGKLYSPVDGEIVNVFDTKHAIMIKSNDNTNILIHVGLETMSLEGKPFDVKVKA
                     GDKVKAKDLIMEVDLDFITSNDLNIITPVVIMDDADSVKRTVKDRIEPGNVDINSIIM
                     EVE"
     gene            complement(19084..19896)
                     /locus_tag="PC465_002840"
     CDS             complement(19084..19896)
                     /locus_tag="PC465_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2650126.1"
                     /translation="MRYKLICTDMDGTLMGKGFEVSEENIKALKEVMEKGIKVALVTG
                     RPYNAMKYFTSVLGDDIYIISTNGTYFKLLGYEYKKVLSKEALKKIYTIGEKYNLNKH
                     FKGCKIVISNNEIGEEHPYRLINSKNKEEDRIEIIENASCETLLEKADNEILKCILFS
                     ENVDSLREAKEEFKKQEDLEVVSSGKINFEVMSKGTSKGIAVKKFCDILGIDSEEVIC
                     IGDNENDISMIKFAGLGIAMGNATDEVKSMADFVTDTNVNDGVAKALRKILS"
     gene            complement(19909..20868)
                     /locus_tag="PC465_002841"
                     /pseudo
     CDS             complement(19909..20868)
                     /locus_tag="PC465_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
     gene            complement(20986..22104)
                     /locus_tag="PC465_002842"
     CDS             complement(20986..22104)
                     /locus_tag="PC465_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2650127.1"
                     /translation="MIAVKKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIEVY
                     KNDKETFTYKQCSSDLTNLKKELNWLKEPDKFSLQNALKDLDNAYKKFFKEKAGFPKF
                     KSKKINRFSYKTNFTNGNIMYCGQYIKLPKLGMVKIRDKQVPQGRILNATISKEPSGR
                     YYVSLCCTDVDIEAFENTNNHIGLDLGIKEFCISSCGEFIENPKYLKKSLNKLAKLQR
                     ELSRKTIGSLNRNKARLKVARLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNM
                     IRNRKLSRLISDVSWSEFIRQLEYKANWHGRQIVKVGKFFASSQICNKCGYKNEEVKD
                     LNIREWICPSCNETHDRDINASINILKEGLRIITIQNK"
BASE COUNT         6878 a         4204 c         2298 g         8765 t
ORIGIN      
        1 aattaatgat ttttaaaata aagatatttt tattttttat ataaacagta cagaataaaa
       61 aaatatttgt gttttccctt ttactattct attttaaaaa tattttattt attttatatt
      121 tctctaaaaa tgtatagttt tcatcacttt catacccaga atcatccact attttaggat
      181 atttaaactt tgtatggaac taaatagatt ttaaaaatgg tattaatgtt atagtatcag
      241 tgggttgatg tcctgaactt accaaaacta tatattctga atctacacca aattgtatat
      301 tatatgctgg tttcaattgc ccatttttca tatgatcttc tttcattctc ataaaagttg
      361 cgtcattatc tgttttagaa taactatttc gttcactcat tatatgaagg tctttagtat
      421 attttttcaa tctatcaata caatcattta attgctctat agatttgttc tttccctttc
      481 catgaacaaa tgttatattt gattcttttg atatttttta accttcttta aaaatttcct
      541 taaatgatgg attttaattt tatctttata aattatttta ataccaaaat caatctcaca
      601 ttttaatatg aagtcagata tattattcat cattttagcc atatttttat ttatagcttt
      661 tttcaaacaa aagtatatct attagcagat gactctattt ctcttgaaga ataaatacag
      721 ttaatgtttg tatatattat aattttcaaa agttgtctag gggttactct atttcctcta
      781 attcgagcat aagtcttata taatttttct aaattcatct actcaataat ttgacttaat
      841 aaccttacag aatcatcttt tggaatcatg taatcaatac ttagtggtaa tttaaattga
      901 taattatcgc cataagtagt ataattaaac tatataccat tttgttttaa cacacaatta
      961 ttatacaaga ctcccaaact cttttgaact tgggattctt gtataataaa gggtgtagca
     1021 ctattttcta gtgatacagc cccatttccc taaattcaaa gtaatattta tagaatctct
     1081 atagattaca ataattattt gacttctaca tcattatatt tctttgaata tactttagtc
     1141 atatagaaat atataggaac tacaattatc atcccaccta atccccaaac tatcttcata
     1201 ggttcatcaa tacctgcttt tatcagtaat aatatactta taataactgc aaatattggt
     1261 ataattgctc ctccaggtat tctaaaattt acatctttac cagcatactt ctttctcaat
     1321 attagtacag ctagacatgt aggaatatat tgaataaatc tagatacaac acttatttga
     1381 gataatgttg tgaatgaacc cgaccatgct attagtaaag ttcctatgac agatactata
     1441 attgctatat aaggagctcc atttttatta gtttttctta tagacttagg cattaatcct
     1501 tgttcaacca aagcagcagc agaccttggt gtaaatatgg atgatgcaat atttatacct
     1561 ccaacagata ctatagttcc tattgtaatt atatacccgc ctataggacc taacatctta
     1621 atggcagcat ctgcaacagg agtagctgac cctgctaagc cattacccaa cacccctata
     1681 cttattccca gtataagcat atatattact gatactacaa acattaccat taccaatgct
     1741 ttaggtacat ttttcttagg gttctccata tcttttgctg caacagctaa agattcaaat
     1801 cctgtaaaag cataaaataa agttatagat actgctacaa aagctgatga cgcactttga
     1861 cctttttgta ttattacaaa tggggtaaaa ttagaaccct ttataaagaa taatcctaca
     1921 gctataaata aaactattgg taataatttt cctatagtca tgatattatt taagtgctta
     1981 gattgtttca ttcccataaa atttataatc ccaagcccta caactaatat accaattatt
     2041 atatttttag taagtggttc tgctgcttgt ggccatacag atgatagtgt tacagcaaag
     2101 aaatttgcca tagtagccca agcaatcata ctaactatcc acttcataaa tccaacaaaa
     2161 tctccaaatg cctcttttgc ataaagatag ggccctccat cagtatcaaa ccaactacct
     2221 gcttcagcaa aacataaagc aatagaaaca gctaaaagca tacaaaaaac taatactaat
     2281 atacttgctg gacctatatc tgtataagca tcaccaggta acccgaatat acctgaccct
     2341 attattgcat tgattcctaa tagtacaata ctccaaaaac ctaacttaat gcctttttcc
     2401 attgttattc cccccaaagc caacttaata tatttatatt ttttatttag atgcttcttt
     2461 aactattgcc ataaatattt ttttcatatt atcataatcc ctagtcatca tttctggatg
     2521 ccattgtatc cctattacaa actcacttcc ttccttttct atagcttcaa ttaaaccgtc
     2581 tttagatgta gctgaaacaa tatatcccgg tgctactttg ttgacaacta agtgatgaaa
     2641 actattaact aaaacttctt tttctcctaa tatttcatat aattttgtcc cctcctttat
     2701 ctgtactgta tgtgtaggta cattagatag atgttgctga ttgtgtttaa tataagcacc
     2761 ttcaattaaa gataaatctt gatacaaact acctccttca gttacattta taatttgttc
     2821 tcctctacat atacctaaaa ctggtttttt catatctaaa gcatgtttta ataatttcat
     2881 atcaaaacta tctctctttg gtgatattgc ccccaactta ttatgaggtt cttctttcca
     2941 tatgagtgga tttacatctt gtcccccaga tagtataagc gcatctatat tagatacctg
     3001 ttcctttata atctcatcat catatacaat cggtacaata tatggtatag ctttacacat
     3061 aactactgat tgtatataat cattatttac ataagccctt tcatagccag gaaacattcc
     3121 tccttcatca attagtaaat tacctgatat tcctattatt ggatatttct ttttagccaa
     3181 tttcttcacc ccttaactta tttgtgaaca ataaaaaatg ctacttctct taaagagcaa
     3241 gtagcatacc aagattttat ttatttgaac attataattt attttagaaa tacttttttt
     3301 gaatacgagt aatataaata actttattta cttatatttt attttaatcc tgtttagttt
     3361 gactttttta aattgtttta agtacaacta ataggtaaaa taggcattta gattttcctt
     3421 tttatcaacc tattaaatac tgtttaatat attttttccc cttctattta attcacttcc
     3481 ctttctacca gattcacata ttatcaaatc cagctctttt aacatattaa gtattcccct
     3541 tacctcacct tctgttatat tgtagcctaa ttcatttatt gaattaacaa taccatttct
     3601 acctatattt ttattaagat tattggcatt ttttaaacac tccattacta actttacttt
     3661 ctctatagat gttctatcct ttaatatact tatttcttta ctaaaatctt cagttatatt
     3721 taataagtta tgaggtaaat catttattaa aataacatcc tcagaactca taatgttaat
     3781 atacatagca gtatttttta attctcttat attacctggc cattcatatg cattaataat
     3841 gtcttgaaca tcttgactaa ttgctctctt ccttttcata aaatgcttta acatagcttc
     3901 tatatcttct tttcgctctc ttaaaggtgg tatatttatg ggcaatacat ttatcctata
     3961 gtataaatct gctctaaatc tatctccttt tatcatttct aataaatttt tatttgtagc
     4021 cgcaattact ctaacatcta tatctattac attttctcct ccaaccctca ttacttgatt
     4081 ctcttgtaat actctaagta atttgctttg taagtatata ggcatgtctc ctatttcatc
     4141 caaaaatata gttccattgt tagcctgttc aaataatcct tttttacctc cttttaaagc
     4201 tcctgtaaaa gcaccttctt catatccaaa aagttcactt tcaagtaaat tttctggcat
     4261 agctgcacag tttatcgcaa taaatggctg actatgtctt ggtgatgcat tatgaataga
     4321 ctgagccatg agttcttttc ccgttccact ttctcccgtt ataagaattg tataatcaga
     4381 ttcagctatt ttcataccta atttcttagt tctttccatc ttcgttgaaa ctgtttttat
     4441 atcatcaaaa gtatatctag caacttgtcc cttttctcta agcttctttg ataggttttg
     4501 ctccaatttt cttatgtaag ttatttcttg aatacaaaaa taatatccag taacccttcc
     4561 aaaactctct atattatact tatttacgtt taagtactta ttattaaatt ttataacttc
     4621 atcatgtgcc ttactcaaac taaaaatctt tttaatattc tcattctcta attcatctat
     4681 atttttccct ataatattac tttgaatatc tagtatatcc cctaaactat tattgcaaat
     4741 aattatgttt cccttatctg ataccattgc catacctaag tttgataaat ttattatgga
     4801 atttagttca tctgctttta tagtaagttc tttgtattta gtatttattc ctgaatataa
     4861 actaattatt tcatctgtat acttaattag cctttcagta atttctttat catccagttt
     4921 gagttttgct attatttgaa taaacgttga actatcaata tacctatggc ctaaatcaat
     4981 aacttcttct atatattttg gaactaaact tgcctctcct ggcgttatag ctatcttaat
     5041 atttctatat tcttcattgg gattgtatgg tataaaattc agatgattta ttcctatatt
     5101 gtataaatta gatattgttt ccaatacagt atgcttatta tcgtttacta ctaatacatc
     5161 tattccttct ggcaatgaaa ataacttata tatatccttt tgctttatac tcctatttat
     5221 agttattatc tttgagacat cttctacata tttttttatt tttaatactc tatcatctat
     5281 cattaccaat attatgtcat cttttattaa ttccttctct gttattttat ttaaataata
     5341 attttttatc attactttat ctttaaatat catttctaga tttttattta agaaacattc
     5401 taatttagac aacccatcag ttactactgc tattgttttc atttgattac tccttttaaa
     5461 atatactcta ctcttttata atatacatct gattttcact ttaacagcac aaaaaattgt
     5521 acatttagta tactaacata ttcctttatt agttttatgt ccctaaatat catagttgca
     5581 atatctatca tatttcctaa acttctatag agcaaaaatt gtgccaaatt aataattttc
     5641 ttaattttat tctaaagttc ctcaatagta tttacagact tagcacttat agcttataag
     5701 tctttatatt attaatctat ttttataggt taattgtaca aatcatatat cacttttacc
     5761 cattaaatgc attataaaaa agatggaata acgattcgtt actccacctt ttttgtaata
     5821 aaaaattgta tatataaaca ctatttacta ctcttctaag tacaaacagt atctacatac
     5881 tataaccttt caccattaga ttctattact tgtttatacc agtcaaaact ctttttctta
     5941 atcctagaca agtctccact tccatcatca tacttatcca cgtatataaa cccatatctc
     6001 ttggccatct caccagtaga tgcacttact aaatctatac atccccatgg agtatatcca
     6061 aataaatcaa caccatcttc tacagcttcc ttcatttgct ctatatgtgc ttttaaatac
     6121 tctatacgat agtcatcatt tatcactcca ttagattctt ttttatcata agctcctaaa
     6181 ccattttcaa ctaccatcat aggtattcta tatctatcat aaatttcatt tagtgcatat
     6241 ctaagccctt cagggtctat ttgccatccc cattcactag acttaagata tggatttttc
     6301 actccaccta atatgttgcc acttgtatta tcttctttag aatcactact tacacatgta
     6361 gacatataat aactaaatgt ataaaaatct acacaacctt cttttaaaat ttctaaatct
     6421 cctttttcca tttttatttc aatattattt tctccaaaat atctattcat ataagttgga
     6481 tattcgccac gcacttgtac atctccacag aaataattca ttactctact atctctttga
     6541 gttttaactg catcatctgg attacaagta taaggataca ttgttgcaaa tatttgcata
     6601 catccaactt gataatttga atctatttca tgagctaact taacagcctt agcacttgct
     6661 acaaattgat gatgtaaccc ttgaaaacga agttgaagta tatctacttg gtttataaaa
     6721 tctgtagtcc cttcatttaa tattccttgt gataagtagc ctcccatagg cattgtagct
     6781 gaatttattt cattaaatgt cagccaatat tttacttttc ctttatatct tttaaatatt
     6841 gtttcacagt aattcatata caagtctatt acatctcttg aaacccatcc attgtatttc
     6901 tctgttattg caaatggtat ttcatagtga gatattgtta ttaatggttc tatattatat
     6961 tttaaacatt catctatcac attttcataa aatttaagtc ctgcttcatt tggttctttc
     7021 tccattccag ttggaaatat tctagtccat gctattgaaa atctaaatac cttaaatccc
     7081 atttctgcaa ataaagctat atcttctttg tatctgtgat aaaaatctat tgcttcatga
     7141 cttggataaa atgttccttt ttctataact ctcgttattc ttttacttac tttttgagaa
     7201 cctccagtac acatatctga acaagaagga cctttcccat ctaaattcca tgctccttca
     7261 cattgatttg ctgctgttgc tccaccccat aaaaaatctt ttttaaatga catacctata
     7321 tcctcctatt ataattcttc accatttgat tctattactt ttttatacca ggcaaaactc
     7381 ttctttttac tgcgttttaa agttccattt ccatcattat ctttatccac atatataaat
     7441 ccatagcgct tcttcatttc tccagtactt gcacttacta agtcaataca tccccatggt
     7501 gtgtaccccc ataaatcaac accatctaac tcaacagcat ctatcatggc ttttatatga
     7561 gcacgtaaat aatcaattct ataatcatca tttatatttc cattttcatc tggattatct
     7621 actgctccta gtccattttc aactataaat aatggttttt gataacggtt atataaagag
     7681 ttcatagtta ttctaagccc taatgggtct atttgccatc cccactcact tgcatctaga
     7741 tatggatttt taagacttgc aaaaacattt ccttctgtta aaatatttac ttttgggtct
     7801 gcacttgtaa gtcttgatga gtaatatgag aacgaaataa aatctactgt gttctcttta
     7861 agtatctttt tatcatcttc ttccatcact atatttattc cttttctctc caattctttt
     7921 aatgcatatg ttggatattc tccacgagat tgtacatcta taaaaaagta attttcccta
     7981 tctttttcta tagatttcca tacatctagt gggttacaag tattaggata agtatttcct
     8041 gctgctaaca tacaccctat tttaaattct tgatttatgt tatgtgctag tttagtaact
     8101 aacgcactcg caactaattg atgatgtgca gcttggtatt ttatttgttc ttcattttct
     8161 ccctcttcaa tatagagacc tgcacctata aatggtaaat gaagtatcat gtttatttca
     8221 ttaaatgtta gccaatactt taccttacct ttaaaccttg taaaaataac ttcacagtat
     8281 tttacatata agtctactag cttacgattt ctccatgctc catatttttt taccaaatac
     8341 atgggaacat caaaatgaca gattgttact actggttcta ttccatactt taaacactca
     8401 tcaaataaat cttcatagaa ttttagtccc tcttcatttg gaacatcctc aactcctgtt
     8461 ggaaatatcc tagtccatgc tattgacata cgatagcatt taaatcccat ctcagcaaat
     8521 aattttatat cttctttata attgtgatac atatctattg cttcatgagc tgggtaatag
     8581 tgttcatcat cacattcaaa cattttcatt ttcccagcca aaactggaaa tctatctttt
     8641 ccttgcggtg taacgtcaac attagctaga cctctaccat cttctttata tccaccttca
     8701 cattgatttg ctgctgttgc tccaccccat aaaaaatctt ttctaagtgc cataattcta
     8761 cctccaataa tttatttata gtaactttat tttaaaataa aaatacatat atataattct
     8821 taattaatag aactctcttt tacgctaaaa cagttatcaa tttctgacta ttatttacat
     8881 gcttttgtgt attttctaca atatccacat aatcagaata attagtaaca actactggtg
     8941 tttctaagca atatccttct tttgaaatac tttctatgtc aaaagttatt aatgtctgac
     9001 cttttttaat cttatcccct tgattaacaa aagatttgaa atatttacct tccaactgaa
     9061 tagtatttaa ccctatatgt atcaatagtt cacaaccatt atcagatata attcctattg
     9121 catgttttgt tggaaataaa gtcattacag tcccatcaaa tggtgccact acttttcctt
     9181 ctttaggtgt tattgctaca ccttttccca atatacctgt tgaaaacgct gcatcttgta
     9241 tctgctccaa agcctttact tcacctttta ttgggctata tactacttct cttttgtttt
     9301 tttctataac gccttgccca ttatcatctt tagaaatttc tactatagca tcatctttcc
     9361 aaaaaaataa tgttaaaaca aatcctacta caatagctac tattattgct attatagttg
     9421 cataaacacc tttcatatct ccagttgttg gatttatata attaggtata ccaaatattc
     9481 caagtccacc cattacataa ctttttacat tcattatccc cattacagct cctgccacac
     9541 caccacctac acagctatat atgaatggtg tttttcttgg taaagttatt ccatatattg
     9601 caggctctgt tacaccacat atccctgaaa taactgcagg tatacacagc tcttttatct
     9661 tcttatcttt taatttaaag tacattgctg ctactactgc tgtttgtgca aaagatggta
     9721 caaatgctcc cactaatatt gtgtcaaacc ccatagtcat aaggtttgac atagctattg
     9781 gtactaatcc ccaatgtaga ccaaatatta caagcacttg ccacaataaa ccagttaatg
     9841 caccacataa aattggtgaa aagttaaata aagctaaaaa tccatttcca actatattag
     9901 aagcataggt agctataggc cctataacca taaatcccaa tggtaaagaa actaataaaa
     9961 ctgccattgg tacaaagaaa ttctttacta catctggtat tattttagca aacactttct
    10021 ccaacttagc tgctaataat actattaaaa ttactggtac tactgttgaa gtgtagttca
    10081 ttgctattac tggtaatcct aagaaagtta tatatactgg tgattcaaat attgttccag
    10141 taaatagatt gtataaaggt tgacctgtag atgctagagt atctaattga atacctgaat
    10201 agcataaaac tgcacctata agcattccaa taaatggttt taatttgaat ttcttagcag
    10261 ctgtatatcc aagaattatt ggcatatact ggaacattgc atctccaatt gcatttaaca
    10321 taatatatgc accatcagtt tctccataca aacccaatgc tgtaaatact gcattaaatc
    10381 cttttatcat accagcagca cacagaactc ctaatattgg ttgaaaaact cctgatatta
    10441 tgtctataaa cttattaagt aatccttttg gcgcatctga atctgaatta tctattgtat
    10501 ctcctcctaa tccagccaaa tcgcacacaa cttcataaac atctggaaca tgattaccaa
    10561 taactacttg gtattgacct gcacttttca ttacagtaac tataccatcc atttttttta
    10621 gcacatcatc atttgctatt gactcatctt ttaatttaaa acgtagcctc gttatacagt
    10681 gagataaact gctaatatta tcctttcctc ctacattcgc aatgatttct tttgatagtt
    10741 gttcatactt tctcattttt tctcctccat tttctttttg aaatatgaag gtttggccaa
    10801 cttaatgtca ccacccaata tatataaacc taattattag gatttatatc tgacttaata
    10861 cttttactta ccactctttc aacgtgaata gttaagtata atttttcctc atctgttaaa
    10921 tcgtagttgt attttttatg tataaattca tccaactttt ctatgaattt ataagcattt
    10981 ttatatttaa cttttattac atttaataaa tcatcttcat tattttcatg taaattatta
    11041 ctaacaattc gttctgcaaa atactttaag tgagtaataa atctatgata ataaactgaa
    11101 tcttcatcaa atactattct gtaatggtat ttaaccatat ttgaaatttc ttgtattatt
    11161 tgtgtaatct catatatagt ttttatactt tgatccattt gtgcattaac tatatgcagt
    11221 gctataaatc cagcttcatc ttctgatagt ctaatttcaa attttttttc tatataatcc
    11281 aatgcctcta accctatttt aaattcactc ttataaaatc tttttatatc ccaaagtaat
    11341 acatttttta cacttactcc ttcacgagct ctttctattg cagtatacat atggtctgtt
    11401 aaagaaatat aaatactatc atttaatctt ttccctagtt tttctttagc atataaaatt
    11461 atttcatctg ataattccat atatcttata ggaatatctg ctattagttc tttaaattta
    11521 tcagatatat ttgggtctga aagtttgaat atcttatcaa ttttatcctt tgatatatgc
    11581 tctcctgtac gttttttata agctaaacct ctccccataa ctactatttc cttatgattt
    11641 tcatcagttg taataattac attattattg agtatttttt caataatcat tgtgatgccc
    11701 cctttattag cattaagtta aaataaatct tttttaatta tttagaatat ttaaaatgta
    11761 atttattaca taaaaaaaaa cctatttatt acacattaaa tagactccca tgagtcctga
    11821 gtaataaata ggtttagctt gtatttaaac aatcactatc cgtttgtatt ttattttaat
    11881 tattatttat tatatgttag caaatttatt ttttagtgtc aactttttct caatatttta
    11941 attttaaata aattatataa attgaatctt caaagtacta tttttatcaa taaacaaaat
    12001 aaaaaaggta ttactttctt taagtaatac ccatttattt ttaatttaag tggtttttct
    12061 taatctcatc aagtagtcca tcttctaaat aaatttctaa tgcacatcct accattgcct
    12121 ttactgcttt gtgaagttta tcataagctt cctcagaatt tgcataattt agaaattctt
    12181 tttcatgaac atataccatt ggacttatat ctaaggctat ttctgtatac atagtagggc
    12241 aaacttgact tacattacct atatctgtag aacctactgg accatcttta ccttctaata
    12301 tatctgttat acctgcctca atcaaattat tctttgttat cttttgaagt actttgttat
    12361 ttattatgtt gtcaaaagaa ttttcaaagt atctataaga aagcttagct cctgtcatta
    12421 actctgcacc ttttgcacag tttataactt ttttagttac ttcatctaaa taacttcttt
    12481 cagcagctct tacgaaaaac ttacaggctg ctttttctgg aactatattt ggagcctctc
    12541 ctccatttga aactatacca tgtattctaa catctgattt tacatgttgt cttagtgcat
    12601 ttatcccagc aaaagtaagt tgtactgcat ctagtgcatt gactcccata tgagggtgac
    12661 tagctgcatg tgctgatacc ccttcaaaac taaactctaa tgaatctatc gccaaagcct
    12721 tacagtttat attattaaaa gcttctatat gcatttgata acttacatca acatcatcaa
    12781 aagctcctgc cttaactaaa tcacattttc ctcctgttgt ttcttcagct ggtgttccta
    12841 ttagtacaat ttttccttta aaattttctt ttaacttact taatactata caagctccta
    12901 gtgtagatgc tgcaatccag ttatgtccac aagcatgagc tggttcttta ttttctccat
    12961 atccaggaag tgcatcatac tcagctaaaa atgctatggt aggtccatca ttatctccta
    13021 attcagctct aaaagcagtc tccatattac aatatggata aactgtatca aatccatatt
    13081 ccttcatttt ttctactaag tattttgatg atatgtattc ttcttcccct aattcaggat
    13141 tgttaaatat aaaattacaa acttcttcaa tttcttttcc aagttcattc tctatctcat
    13201 aagctctctt ctttatactc tctatcataa tttacctcct actagaatcc tagatataat
    13261 cctattgtca aaaatgccat tacaagaatt gttaatacta ccattaaagg aattacgaat
    13321 ctaacccact ttgaccaagg aatattggct actgctagtg ctcccattaa aacacctgat
    13381 gtaggtgtta ttaagttagt tacacctata ccaaattgat aagctgtaac tatcatttgt
    13441 cttgatacat ctactaagtc gccaagtggt gcaagtacag gtattgtaag tgatgcaagc
    13501 cctgatgctg atggtattaa aaatgctatt aatccttcta ttaagaaagt taaatttata
    13561 aatatagttt ttggtaatcc atttaataaa tttgctgcag aatttaaaat tgtatctatt
    13621 ataaatccat tttctgctat tattacgatt ccacgtgcaa atgctataca caatcctgct
    13681 gtaattaaat ctcctgctcc acttataaat gaattaacta tctcatcttg tttaagccct
    13741 gatgctattc ctgatattat acctatagct gtaaatatca ttgcaatttc agttatgtac
    13801 cattctagtc ttaaaactcc atatatcata atcgccatac ctattgtgaa aatggctatt
    13861 accatggctt ctctttttgt aaattccttt atatttgtat cactattaac cattaattct
    13921 tgatttagtg atatatcgtg tactaaagat tttttagggt cttttttaac tttattggca
    13981 tacatcataa caaatcctat agatatagcc atatatatta taaacataac aactctaaac
    14041 tctattccag aacctggtac tatttgtgat aatgcttgtg ctattcctac agagaaagga
    14101 ttcgtagtag ctgctccaaa tccagctgtt gctcctataa atactgtggc cactgctgtc
    14161 aatgaatcat atcccatact ggtcataagt ggaataaata tcatataaaa aggtagtgtc
    14221 tcttcactca ttccaaacgt cgtcccacct agtccaaata gaatcattga aatcggtatt
    14281 attaaaaatt gaaacttctt cattttattt acagtatgag ctataacagc ttctatagct
    14341 cctgttttat taactatccc aaaagctcct ccaactatta aaacaaatcc aactacttca
    14401 gctgcatcta taaatccgtt tataggtgct gtaaatacat cagtaattcc ttgtggattt
    14461 gatggtgctt tttcataagt tccagctaca acaactgacc ttccgtctat atctactctt
    14521 tcaaaatttc cacttggcac tatccaagta agaattgcca ttaacactat tagcaaaaat
    14581 attattgtaa gtgtctgtgg catagtaaac tttttctttt ttaaactgct catttttaat
    14641 ctccccactt tttaaattaa atattttatt attgcatctc tttatcctat tttgtataga
    14701 tgtaaaaaag ctcaacatgg atacatgttg agctaaatgt gctaaataca acatacctgc
    14761 atcttccctt tatcttgttt aagatagctc tccatcaaaa ttcgggataa ttttgatgac
    14821 agtactgtac ctattaaata cagtcccagc actagcttcg gacactagca cttcggcact
    14881 tactcctttt atattgcctc attggtttcc aacctcttca atattaatct tagtaaatgc
    14941 aacctctacc tcaatctgtt tgttagatga ggtaattctt attaattttt attaattcaa
    15001 agtaattgta gcataatatg tcgagattgt aaatattttc agtataataa ttcttacttt
    15061 atgatttcat tccatttttc acaaataatt ttttctccat ataatttaaa tactgtagta
    15121 tattttaaat acacacaaac tttccacaaa ttttaaatta ttataatacc tttataataa
    15181 aaaataaaag ctatgtaaac ttatcaattt acatagcttt atatacatta atctactcca
    15241 agtacagctt taagctttga tgctattgta ataactcgtg gaccaaatat aacttgaact
    15301 gagtttttct ttttaacaac tccacttgca cccaattcat ttacccagaa gccatcttca
    15361 tagaatccat caattgaatt tagctctacc ctaagtctag ttgcacagtt tgtaacattt
    15421 tttatattat tacttcctcc taaaccttct attatagaat gtacaagctt tgtatcttta
    15481 tcatctactt cctcttctac tgcattgttg tatgctgttt taccagcatc tacagattgt
    15541 ctttctctat attctttctt actataaagc ttaacttctt ctgaacttct tcctggtgtt
    15601 tttatatcaa acttcttgat tgcccatgta aatattatat aagtaactat aaaaaatatt
    15661 ggtatcaaaa ataataatgg taacgcatcc actttttgtg gttgtaataa attaggaaac
    15721 atatttctaa atgattctcc cattatagaa acattgaaca tttctgtaaa tacatacgtc
    15781 aatcctgcca gtggtacata tgctacaaaa tacaataatg gtgcaacaaa taggaatgta
    15841 tactctattg gttccgttac ccctaccaac atggctgtta ctattgctgg tatcaatata
    15901 cttattgctt ttttcttatt agcattatca gccaacttat acatagctaa agctgctgct
    15961 ggtaatattg caaaatgtat taataaacga cctgttgtga agttacgagt tatataagat
    16021 agtgtatctg ggtctcccat ttgagctaat cttatattat taacaccctc gtaaattgct
    16081 ccacctactt ccattgttcc acctactctt gtatattcta tagggaatgc aattaagtga
    16141 tgtataccaa atggtaataa tgctttatcc attgctccaa aagtaaatgt tcctaataat
    16201 ccactagaac ctatccaatt accaagttta gataatgcca accctactgg tggccatata
    16261 aggtacattg ctgtacccaa tactattgat gctataaaca tcataatcat tgaaaatctt
    16321 ggacctgaga aaaaagataa tgcactagga agttctatgt caacaaattt gttatgtact
    16381 gcactagcta caaatccagc tattatagct ccaaatatac tacaatcata tgaaaagatt
    16441 cctaagaaag aaccatataa agaacttcga ctatatgctt ctgcctctcc taatccagat
    16501 gccataaacg cttctgctgt aactgtatct gaatttatac catttgctgc taacaatgta
    16561 cttataactg tgtgcattcc tataaataaa acaattcctc ctaatgcacc ccatcctttt
    16621 tcctttttag ataatccaaa ggctatacct gtaacaaaga atattggtaa atatctcatt
    16681 accataaatc ctaaatcgtt tattacttta aagaatacat ttataaatga cccttctttt
    16741 attagtccgc taagccctaa tgcagaaacg ttttccatat ttgcaaaagc tgaccctaat
    16801 cctataaata ctcctgctac aacaagtaat ataacaggta tcatcattgc tccagaaagt
    16861 acttgtaatt tatccttcat agtattattt cctccatttt tattgaaatg ccaggctata
    16921 taatgcatat atatatactt ctattgcttt gtataatgta tctatactta tattttcatt
    16981 tgcctgatgt gaatttggat tatccccctc tattgtgggt ccaaatgcaa ctccattttt
    17041 taacactctt gcataagatg cagctccttt tgtaaaaagt tcggcttctt ttccaaaacc
    17101 ttgtttatat gcacttgata atttatttat taattcacta tctggtttta catacagtaa
    17161 ttttaaatcc ttatatatat caactattaa attttctttt tttccaattt cattaattct
    17221 attagttata aactcccaac ttataccctt aggatatcta aagtctattt tcatattcaa
    17281 ttcatttttc tctaagaaga tactcattat acatattgta gaaactccca tatctacatc
    17341 ttctttatat atccctaatt tttttccatg attatcatct gtaaagtatg aatttaaaat
    17401 atcccttatt ataacgcctt tatcatttaa ttttttaatt ttctctaaat cttttgctaa
    17461 actaaatgca cagttatatg acctgtgtgg atttctcgat aaagcccttt ctcctgtata
    17521 tcttactaat actttacctt cttctagttc ttctatctct gtataataag ctaatgattc
    17581 tactaaatct ttcttatcat tagttttaaa aacagcctca attttgtcac atacaaatcc
    17641 atcttctttg tttgacttta tatcaactaa attgtgattt ctaaatttat ctttatctat
    17701 tttctttctt agattgaagt ataaaatacc tttttctcca tttactattg ggaagtttcc
    17761 atctggagaa aatgcaaatt ttggctgttc attgacacta aagtaatgct ccatacattc
    17821 ccaagtcgtc tcttcagctc cacccactat caacctaatc tttctcttcg gcttttcatt
    17881 aagttctctt aagaaaagta atgcatataa aatccctatc aaaggtcctt tgttgtcatt
    17941 aactcctcta ccataaagat agttatcttt ttgacatact ttaaaaggtt tactcttcca
    18001 aagttcttta ttatatattg gcaccacatc tatatgatta agcaccccta ctacttcttc
    18061 tccttctcca tattctatat gaattgcata tccatcaaag tcttttacaa caaaatcttt
    18121 gtcttttgct atttgaataa gcttatcgaa ggcatttctt atttctatcc caaatggttg
    18181 atttatatct gttgtacttt catctctaat tgaaggtatt tcaactaaac ttctaatatc
    18241 atttatgata ttttcttgat tggattttaa ataatcaata attagttctt tgtttactat
    18301 catcttaatt atttatcacc cctttatatt aattttacaa agcatttcag ttcatatcta
    18361 cattataaat tttgaatatt attttttcaa tatttcaaat acttctctaa gttaccataa
    18421 tgatacggta aacaatcaac agattatgac aaaatcatac tatatctatt actaatattt
    18481 taacttatct attacgtctt ttttaatgta agtttattcc aaaaatacat aaaaaaagat
    18541 gtagccttag ctacaccttc ttatatctat tcaacttcca ttattatgct attaatatct
    18601 acatttccag gttctatcct atcttttact gttctcttaa cagaatcagc atcatccatt
    18661 ataactacag gagttattat atttaaatca tttgacgtta taaaatctaa atctacttcc
    18721 attattaaat ctttagcttt taccttatct cctgccttta ccttaacatc aaacggcttt
    18781 ccttctagtg acattgtctc taaacctaca tgtattaata tatttgtatt atcattactc
    18841 ttaatcatta ttgcatgctt tgtatcaaat acattgacta tttcaccatc aacaggagaa
    18901 tataacttac cttcacttgg tattattgct actccatctc ccatcatctt ttgggcaaaa
    18961 actgcatctg gaacatcttc taagttcact aaatttccct taaaagggct atatattttc
    19021 tcaatcttat tttctttttt cttaaatata ttaaacataa cacactctcc acattataaa
    19081 attttatgat aatatttttc ttaaagcttt tgctacacca tcatttacat tagtatcagt
    19141 tacaaaatct gccatagatt ttacttcatc tgtagcattt cccatagcaa taccaagacc
    19201 tgcaaattta atcatggata tatcattttc attatcacct atacaaataa cttcttcgct
    19261 atctatacct aatatatcac aaaatttttt aactgcaata ccttttgaag tacctttgct
    19321 cataacttca aaatttatct ttccagaact tactacttct aaatcttctt gttttttaaa
    19381 ttcttccttt gcttctctca aagaatctac gttttctgag aaaagtatac attttaaaat
    19441 ttcattatca gctttttcta ataaagtttc acaacttgca ttttctatta tttcaattct
    19501 gtcttcttct ttatttttac tatttattaa tctatatgga tgttcttcac ctatttcatt
    19561 gttggatata actattttac agcctttaaa atgtttgttt aaattatact tttcacctat
    19621 tgtatagatt ttctttagag cttctttgct caaaaccttc ttatactcat atcccagtaa
    19681 tttaaaatat gtcccattag ttgatataat atatatatca tcccctaaaa cacttgtaaa
    19741 atatttcata gcattataag gtcttcccgt aactaaggct accttgatac ccttttccat
    19801 gacttctttt agtgctttaa tattttcttc tgatacttca aatcctttac ccatcaaagt
    19861 accatccata tcagtacaaa ttaatttata tcgcatttgt atcacatcct agtaagattt
    19921 ttctaatatt tcaacaaggt cttctttctt tccaaaaggt aaaaatccta aaactggaca
    19981 gcttgttatt tgttctaatt gttcctttgt tacattaaac tcagacattt ttgtcttaag
    20041 tcccactctc tttaaaaaac tttctatttc atttcctaaa gttttagctg cttcatcatc
    20101 ttccactttt tctaattctt ggtttagcat tctcgctact ttggcaaatt tctctatatt
    20161 atccttatag aacttttctg caaattttgg gaacactata gccaaagcct caccatgagg
    20221 aatatgtgta actcctccta ttatttcact tagtggatgt ggtgctgctg ctccagcatt
    20281 tgccagtgaa tttcctccta atgtatctgc tactgctaac tttgttctgt attctatatt
    20341 atttttatct tccattactt taggtagata gttaatgact aattccatag atttttcaga
    20401 cattatctct gtaaaatcat tagcatttgg atttatataa ctttcaaatg catgagtaaa
    20461 agcatcaaat gctgttgatg cagtaattct ctctggcaga gttaacataa gctctgggtc
    20521 aactatacat tcttttgaga aacaattttg atgaaatatt gtatttttct cgcttcctct
    20581 cgatattact gctgcttgtg taacttggct tcctgttcca gaagtagttg atacagctat
    20641 taatggtaat tctttttcac ttaccttatc gtatatttta aatggatttg tatatgtact
    20701 aaacatataa tcccaatcta tcttttctaa accaaaagtc aatgctaata cttttgcagt
    20761 atctatactt gaacctcctc caacagctaa aacaacatct acagattctt ttttagctaa
    20821 ttcaaaccct tcatttatta attctacagt tgggtttggc tctactctct gaacctccca
    20881 tgactaaagt cacagggttc ctgcttcaca gaattttgca tactaaaata tgtcttacta
    20941 attctccaca ggccatcccc gtagttccta cggttcttac ataagttatt tattttgaat
    21001 tgttattatt cttaatcctt cttttaatat atttatactt gcatttatat ctctatcgtg
    21061 agtttcatta caactaggac aaatccattc tcttatattt aagtccttca cttcctcgtt
    21121 tttataccca catttattgc atatttgtga acttgcaaag aatttaccta cctttacaat
    21181 ttgtctacca tgccaattag ccttgtattc taattgacga ataaactctg accatgatac
    21241 atcagaaatt aagcgagata gtttacgatt tctaatcata ttctttactt gtaaatcttc
    21301 tatgcaaata atatcattct cttttattaa tttagtagat agtttttgta gaaaatcatt
    21361 tctttgatta gctatatgtt cttgaagtct tgcaactttt aatcttgctt tatttctatt
    21421 taaactaccg attgtctttc tcgataattc tctttgtaat ttagcaagct tgtttaatga
    21481 cttcttaaga tacttaggat tttctataaa ttctccacaa cttgagatac aaaattcttt
    21541 aattcctaaa tctaaaccta tatgattatt agtattttca aatgcttcaa tatctacatc
    21601 agtacagcat aatgatacat aatatctacc acttggttct ttagatatag tagcattaag
    21661 tattctacct tgaggtactt gtttatccct tatcttaacc ataccaagtt taggtagttt
    21721 tatatattga ccacaataca taatgtttcc atttgtaaag ttagttttat atgaaaatct
    21781 attaattttc tttgatttaa atttaggaaa tcctgctttt tctttaaaga attttttata
    21841 tgcattatct aaatctttta aggcgttttg tagtgaaaat ttgtcaggtt ctttaagcca
    21901 atttaattct ttttttaaat tggtcaaatc agaactacac tgtttataag taaaagtttc
    21961 tttatcgttt ttataaactt ctattctttt agcaagatac ttattatata caaatctaca
    22021 acatccaaaa gttttgttaa ttaactcttg ttgtttttta tttggataca ttctaaactt
    22081 ataagctttt ttcactgcta tcacctcact ttaattgttt tttgatacac tttttaatga
    22141 tttta
//
LOCUS       DAMJXI010000060        21603 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.062, whole genome shotgun sequence.
ACCESSION   DAMJXI010000060 DAMJXI010000000
VERSION     DAMJXI010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21603
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.062"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            103..1554
                     /locus_tag="PC465_002843"
     CDS             103..1554
                     /locus_tag="PC465_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HDF2650128.1"
                     /translation="MDFFNGILTSINNAVVYVNNYLWSYILIIMLVVIGIYFTIKTNF
                     VQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGG
                     PGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
                     ILITICYGFVFNAVQANTVSLAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSE
                     IIVPVFAGLYILVALAIVVMNITEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRG
                     LFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSS
                     GATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLN
                     VFRVFVVGMVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQK
                     KSGIKDPVFIADEIEGLEKVSEWHRELSEEHLG"
     gene            complement(1774..2235)
                     /locus_tag="PC465_002844"
     CDS             complement(1774..2235)
                     /locus_tag="PC465_002844"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HDF2650129.1"
                     /translation="MIYEGKLIGKDLKIGIINSRFNEFITSKLLSGAEDCLLRHDVSP
                     ENIEIVWVPGAFEIPLVAQKMAKSGKYDAIICLGCVIRGATSHYDYVCSEVSKGIAKV
                     SLDSELPVIFGIVTTENIEQAIERAGTKAGNKGYDCAMNALEMANLFKSLN"
     gene            complement(2340..3533)
                     /locus_tag="PC465_002845"
     CDS             complement(2340..3533)
                     /locus_tag="PC465_002845"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HDF2650130.1"
                     /translation="MFNTIEEAIEDIKNGKMVIVVDDESRENEGDLLMAAEMATPESI
                     NFMATYGRGLICLPATEKKFKSLNIPLMVRENTDTFQTAFTVTIDGADTLTGISAYER
                     AETVKLFCDENSTSKDFKTPGHIFPLIAKTGGVLVRDGHTEASVDLARLAGFKEIGLI
                     CEIMKDDGTMARVDDLMIFKEKHNLKIITIKDLIEYRKINETTIEKVSSAFLPTKYGN
                     FEIIGYRDTYSNEEHIALTYGNINIENTLVRLHSECLTGDVFHSLKCDCGLQLESSMK
                     KIVENGSGVLIYMKQEGRGIGLLNKIKAYKLQEEGYDTVEANLMLGFEEDMRDFYMAA
                     QILKNLNIKSINLLSNNPDKINQLEKYGIKIENRIPINEEINDFNKLYLKTKKDKMGH
                     LLDII"
     gene            complement(3556..4221)
                     /locus_tag="PC465_002846"
     CDS             complement(3556..4221)
                     /locus_tag="PC465_002846"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HDF2650131.1"
                     /translation="MFTGIVEEVGILRKITANGKSGKVTILSNKILDGTNLGDSIAVN
                     GVCLTVSNLGKNEFTADVMMETIRSTNLGLLNANDKVNLERAMSLSSRFGGHIVTGHV
                     DGKGTICKFEKDENAVLVSIRPDKKLLSSMILKGSVAIDGVSLTISYLDDEIFKVSII
                     PHTKINTILLTKNVGDFVNLESDVIGKYVNNFMANNYKELNSNSSNHKSNIDKDFLFK
                     NGF"
     gene            complement(4255..5367)
                     /gene="ribD"
                     /locus_tag="PC465_002847"
     CDS             complement(4255..5367)
                     /gene="ribD"
                     /locus_tag="PC465_002847"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HDF2650132.1"
                     /translation="MNFVNQKEKDIYYMKKAIELAKNGEGFVNPNPLVGCVIVKDSNI
                     IGKGYHEKFGSNHAEVNAINSAKQSLKDSTLYVNLEPCSHYGKTPPCVDKIIQNKIKR
                     VVISTLDPNPLVCGNGVKKLKDNNIDVTVGILEDEARDLNEAFFYHIKNKRPLCIVKS
                     AVSLDGKIATKSLESKWISNESSRYLTHKYRNKYQSIMVGINTVLNDNPLLTCRLNQE
                     KVSHPTRIVIDTHLKLPLNSNLVKDKTSKTIVFTCCKESIKLSMLKENNVETIISPSK
                     NNLVDLEFVMYKLGELNIDSVLVEGGATLNDSLFRNKLVDKVKLFLSPKIIGGKDAPT
                     FVSGEGINHLSDSTQLTINNVTLIDGDILIESDVLN"
     regulatory      complement(5499..5620)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            5809..8292
                     /gene="recQ"
                     /locus_tag="PC465_002848"
     CDS             5809..8292
                     /gene="recQ"
                     /locus_tag="PC465_002848"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HDF2650133.1"
                     /translation="MNKKLLEILSKYYGYTSFRKGQESIINSILSEKDVLAIMPTGGG
                     KSICYQIPALILDGMTIVISPLISLMKDQVDALKTMGISAAFINSSLSSKEFNEILNN
                     IRKNNYKILYIAPERLDAQEFIELINNNNVSQVAIDEAHCVSQWGHDFRLSYRRISDF
                     IKNLPKRPIVTAFTATASEEVRTDIINLLCLENPDYYITGFDRENLSINIVKSSSKNK
                     YILDYIQNHKNESGIIYVATRKEVENIYNGLSKRNISVSKYHAGLSKNERSKNQEDFI
                     NDNVDIMVATNAFGMGIDKPNIRWVIHYNMPQSIENYYQEIGRAGRDGEKSECVLLFS
                     PGDVHIQKYLIDIGVENPERKLFQHKKLQYMIDLVYSNSCYRKTILSYFGENYIDNCN
                     NCSNCLVEGEIVDKTIDAQKVISCVARMKRSYGVTTIVDVLRGSKNKKILQLGLNTLS
                     TYNIMRDYSSEDLKNFINTLVSHGFLDLVETLGNGNRGSFPTIRLNEMSMKVLKGEVK
                     VEFKEIVMTKSLEVEDELYNALRELRHSIASEERIAPYMVFGDGTLRAMSSSYPINKE
                     EMLDISGVGEIKYQKYGRDFEAAIKEYVEKNNINKKIDEKNVDSKNVNSDFLEVNTDK
                     VLYEKLLVIREEYATKEKLPAYMILANKALKEISGRYPLDEEQLKDISGIGGVKFEKY
                     GASILAEVNKYVKENNINVIWEKKGKRKLILDGESRKNNEIALDLLNQGKDIQSISQE
                     IEVSLSTIIGYVHDYVKDGHSISFELGLENFYNEDKKKMILEVCEKVGYDNLNNIKRK
                     LPDSIKYENIRAVILDSYLENLKNNIIAE"
     regulatory      8381..8492
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            8634..9935
                     /gene="thiC"
                     /locus_tag="PC465_002849"
     CDS             8634..9935
                     /gene="thiC"
                     /locus_tag="PC465_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HDF2650134.1"
                     /translation="MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVI
                     PANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSN
                     YGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFI
                     TIHAGLTRSVCQKIKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEY
                     DVTLSLGDACRPGCIKDSTDGVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIE
                     ANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHL
                     RLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPE
                     KAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI"
     gene            9989..10183
                     /gene="thiS"
                     /locus_tag="PC465_002850"
     CDS             9989..10183
                     /gene="thiS"
                     /locus_tag="PC465_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HDF2650135.1"
                     /translation="MKVNGKEIEFEKDLTVIDLLNKYNLKSDRVVVEVNLEIIEESNY
                     NTYVLKDEDIVELISFIGGG"
     gene            10176..10979
                     /gene="thiF"
                     /locus_tag="PC465_002851"
     CDS             10176..10979
                     /gene="thiF"
                     /locus_tag="PC465_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HDF2650136.1"
                     /translation="MVKIKIFVNELLTDVEENITAYKVRDSYNNKCDVLVLNGYPIKT
                     DMPLCENDKLTLIQKGVKPSLDELESLLIARHTPNIHNKLKKGKVAILGLGGLGSNIA
                     ISLARIGVGELLLIDYDVVEPSNLNRQQYFIDDIGKLKTDAMIENIKKINPFIKLNKR
                     DIFLNKNNMDTIKDSDLIIEAFDDASCKAQVCNYVLINLKDKYLIASSGMAGYYDSNI
                     ITTKKIKDRFYICGDFVNEAKFGEGLMAPRVAICANHMANLATQILIDM"
     gene            11042..11812
                     /locus_tag="PC465_002852"
     CDS             11042..11812
                     /locus_tag="PC465_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HDF2650137.1"
                     /translation="MDKLILGGHEFNSRLLVGTGKYGSNNILPEVIKESGSEIITMAL
                     RRVDLDNKQENILTYIPKEMTILPNTSGATNAEEAVRIARISRKMGCGDFIKIEVISD
                     TRYLLPDNEETIKATKILADEGFIVLPYMTPDLYAGRRLIEANAAAVMPLGAPIGSNR
                     GLQMKEMIRIMIDELDIPIIVDAGIGKPSQAMEAMEMGADAVLVNTAIASAGDPVQMA
                     RAFKLAVEGGREAYIAKTGNVSEFANASSPLTGFLGNL"
     gene            11829..12932
                     /gene="thiH"
                     /locus_tag="PC465_002853"
     CDS             11829..12932
                     /gene="thiH"
                     /locus_tag="PC465_002853"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HDF2650138.1"
                     /translation="MSFYDVIEKYRDFDFDGYLNNVTDNDVLRSLSKDKLEDFDILNL
                     LSKTAVKHLEDMAQKAHKLSVQYFGKTVCLYTPMYIANYCVNQCVYCSYNIKSGIKRK
                     KLTMDEIREEGEAISKEGFKHLLVLTGESSFHSSVEYIGEAIEILREKFPSIGIEVYP
                     MEVEEYKYIVDKGVEGLTVYQETYDEEIYKRVHIKGPKSNYKFRLDAPERGAKAGMRT
                     LSIGALLGLNDFRKETFFTILHGKYLKTKYPHIELSYSTPRMRPFKGCFEELVDISDT
                     DLVQAMVCMRLFDPHAAINISTRENLEMRSHIIPLGVTKLSAGVSTDVGGHSQDEHDT
                     AQFKINDESTVKDVEKMLNSIGYQHVFKDWERF"
     gene            12933..13622
                     /locus_tag="PC465_002854"
     CDS             12933..13622
                     /locus_tag="PC465_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HDF2650139.1"
                     /translation="MYLITNRKLCSEERYLEVIKESILSGVENIIIREKDLEYQELRK
                     LYMKIKTKINCIDFQEQISDESLKTNINQKEFRNKFKVNFIINSNIEFFEKVDCQGIH
                     LPFKLFLNLIENKYNFNENKILGLSLHKVEEVDYLEKLIRNQNIKIDYITLSHIYETK
                     CKEGLNPKGIELLKEAKKITDIKIIALGGILPSNVKETLKYCDDFAIMSTIMRSKDIK
                     KTISNYNEKLN"
     gene            13810..15204
                     /gene="yfcC"
                     /locus_tag="PC465_002855"
     CDS             13810..15204
                     /gene="yfcC"
                     /locus_tag="PC465_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HDF2650140.1"
                     /translation="MTDSKKKRFIIPHTFTIIFLLIVLMAILTWIVPSGEFSREDVEG
                     RMVVVPGTYQSVESNPQGFADVFKAPIEGFIDSAEVVGFVLIVGGAFGIVNRTGAIEA
                     GIASVISKFKGKELLIIPISMILFGLGGTTFGMAEETLPFYMIFVPLMTSLGYDSLTA
                     IAIVFIGAAAGAAASTINPFSVGIAQALAQLAPGSGVTYRVVIFIAYILISIAFVMYY
                     AKKVKENPESSIVYEIDKNNKSILNQTSTEIKEFTFKEVSVLAIFGIGMAIMIWGVLS
                     QGWYIPEISMCFAAIGVLSGLVGRLSQIEISESFIDGAKDLASAALAIALARGIVIIA
                     QNGFIIDTILNSAAAFLGGLPKVIFVYLSFFLEAALAFLIPSSSGLASLTVPVLAPLG
                     DLVNISAQVIVTAYQFGVGLTNFITPTSGVLMGALAVAHIPFSKWVRFIMPILLILTA
                     VSLVFLTIGIYIGF"
     gene            15721..17088
                     /locus_tag="PC465_002856"
     CDS             15721..17088
                     /locus_tag="PC465_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HDF2650141.1"
                     /translation="MGLKEFDFIEESIDMLRTMSPTLETISDEIEEYFENILDEKNQE
                     YINVTSRIKSESSLREKIIRNRYLKKYGEASNLIHNVSDLIGLRIECRFIEDENKIYR
                     LLRRYFNKTDDKINYYNKENKNIKLKLSERQPNKQKNGFEIYKIDGVFAYLDREVKFE
                     LQIKSLVNVFWSEIEHKIIYKNNTYLLADKFIKDMMDSIKNNLTMIDNQLLSIYKNFH
                     SGKSFNMKVSKKEIEKLFAKLVYDAFSEKMNKSIGFVVDFKKPCETILNYSFNKQDIS
                     DEVLGNFMLDEFARLNEIVNKDIDFNEQIEFEREPTFDDKFCKDLGNHFRSRLNTEFP
                     WNLFFRILFEIEPYNNTKDFENFVEFIKENVLLEENREQLLCQFEEDSKLIIEDIYDC
                     IFNSISEIDSVEILYNYNLEKINFTSSEIINCICREYECYGEYLEEKEKLMNTFKEKI
                     IQIFE"
     gene            17113..17721
                     /locus_tag="PC465_002857"
     CDS             17113..17721
                     /locus_tag="PC465_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HDF2650142.1"
                     /translation="MRHFSNIYELSKIILEEAICIEKTGVILAGGRNSRMGRDKAFLE
                     LHDKLFIEIAIEAFKNFDELIIISNNEELYSKYDIKVYNDIVKDVGPIGGIYTALEYA
                     KYDIVTIACDMPYLNNQIVERIANKMNDKSVISVTNGKLQPLCSGYKKSIINKVSLCI
                     RENDLKLRSFIDKIDKSYIYFDEEDLFLNVNTVDEYEKLTKV"
     gene            17769..18140
                     /locus_tag="PC465_002858"
     CDS             17769..18140
                     /locus_tag="PC465_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HDF2650143.1"
                     /translation="MNLLKCDSWAVILNNSDKESKAYKILDELKRNMYKVVAIDEEKK
                     PIEGIDVYECLKDVPHNIDVVAIIDKQSKMDVILEEVELLDIQNMWFEKGSFSEMMIK
                     KTKDLKLNIEYNLSLYDELTR"
     gene            18319..18657
                     /locus_tag="PC465_002859"
     CDS             18319..18657
                     /locus_tag="PC465_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HDF2650144.1"
                     /translation="MLIVTTEKVEGKKISKVLGLVRGSTIRAKHVGKDIGASFKNLVG
                     GELTGYNEMLTEARQIAIGRMVEDAKAKGANAVIAFRLSSASVMQGAAEMLAYGTAVV
                     LEDDNSILEK"
     gene            19124..19627
                     /locus_tag="PC465_002860"
     CDS             19124..19627
                     /locus_tag="PC465_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MogA/MoaB family molybdenum cofactor
                     biosynthesis protein"
                     /protein_id="HDF2650145.1"
                     /translation="MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGAYKVTEYVLI
                     KDDKEMLKENIIRLCNSNKIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRM
                     KSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATE
                     CATKKSE"
     gene            19674..20633
                     /gene="moaA"
                     /locus_tag="PC465_002861"
     CDS             19674..20633
                     /gene="moaA"
                     /locus_tag="PC465_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HDF2650146.1"
                     /translation="MIDKYGRKIDYLRISLTDKCNLRCVYCMPPDVKFDKNYINENLS
                     FEDYKFIIKAMAEQGITKIRFTGGEPLLYPKLNELIKFTKEECGINNIGMTTNAIGLS
                     DRIFELEKCGLNKVNISLDSLKEYKYKSVTRGGNLKDVLKSIESCLNLGIKVKLNCVA
                     ISGFNDDELKDFMFLTVKSPIDVRFIELMPLGEANRVYKKGYFNVKEMIEKIYGLYKV
                     KNDEKSTAEYYMFKGAKGRIGIITPLSCSFCNTCNRIRLTSSGAIKLCLHSKEEIDIK
                     PFLHKPLLFRESMKDIIKQKPEKHHLLENKCSDTNRRMYEIGG"
     gene            20637..21107
                     /gene="moaC"
                     /locus_tag="PC465_002862"
     CDS             20637..21107
                     /gene="moaC"
                     /locus_tag="PC465_002862"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HDF2650147.1"
                     /translation="MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKN
                     GQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLVGCDLEFDVDDSMSAIKIYATCK
                     SLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE"
     gene            21143..21574
                     /locus_tag="PC465_002863"
     CDS             21143..21574
                     /locus_tag="PC465_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HDF2650148.1"
                     /translation="MAKVVSINISEKKGVIKVPVQCAELKINHGIVGDAHAGNWHRQI
                     SLLGKESIDKMKMKGFDQLKYGDFAENVTTEGIEVFSLPVGTKLRIGQCEVEVTQIGK
                     KCHNGCEIKKLTGDCVMPREGIFVKVLKEGIINVNDSIDVI"
BASE COUNT         8326 a         2340 c         3741 g         7196 t
ORIGIN      
        1 atattataat taaattaatg aatttttaac aaggaattat tcattttttt gattttaaga
       61 tttattgaga aaacaaaact aaataggggg gtaattaata taatggattt tttcaatggt
      121 attttaacga gtattaacaa tgcagtagta tatgtaaaca attacttatg gtcgtatatc
      181 ttaattataa tgttagttgt aattggtatt tactttacta ttaaaacaaa ttttgtacaa
      241 ttcagatatt ttatagaaat gtttagactt ctgggtgatg gtacagcgaa taaaaatgca
      301 aaaaaggaag gaaaaatctc ttcatttcaa gcattttgta taagtacatc ttcaagagtt
      361 ggaactggaa atatagctgg aatagcaatt gcagtggtag caggaggacc tggtgctgta
      421 ttttggatgt ggcttatagc attaattggt tctgcatcaa gctttgttga gagtacatta
      481 gctcagattt acaaagtgaa agatggtcaa gcttttagag gtggaccagc gtattatatg
      541 gaacaaggtc taaataaaaa atggatgggt attttattct caatacttat aactatatgt
      601 tatggttttg tatttaatgc agttcaagca aatactgttt cacttgcatt taataatgca
      661 tttggaataa gtaaaatggc tatgggaata ggtcttggaa ttttaactgc aatagttatt
      721 tttggtggag tgcatagagt tgcaaaagtt tctgaaataa tagttcctgt atttgcagga
      781 ttatatatat tagttgcttt ggctatagtt gtaatgaata taacagagat accaagtgtt
      841 atagcattga tagttgaaag tgcatttgat tttaaaggaa tggcgattgg tacgtttatg
      901 ggagttgtaa tgactggagt gaagagaggt ctattttcta atgaagcagg tatgggtagt
      961 gctcctaatg ctgctgcaac agcacatgta actcatcctg taaaacaagg tttaattcaa
     1021 tctttaggtg tttttacaga tactataata atatgtagtt gtacagcatt catggtatta
     1081 ttatattcag gttatagtag tagtggagca actggaattg aattagctca agaagcttta
     1141 actcatcata taggaccagt tggaaatata tttatagcag tttgtatatt cttgtttgca
     1201 tttagttcta tagttggtaa ttactattat ggtgaatcaa atatggagtt tatgagtgga
     1261 agtaagacta aacttaatgt atttagagtt tttgttgtag gtatggtttt atttggttca
     1321 cttactcaag tagatgtagt ttggaatctt gcagacttat ttatggcatt gatggcgata
     1381 ataaacttaa tagcaatagc acttttagga aaatatgcat ttattgcttt aaaagattat
     1441 acaagtcaaa aaaaatcagg aataaaagac cctgtgttta ttgcagatga aatagaaggc
     1501 ctagaaaagg tatcagagtg gcatagggaa ttatctgagg aacatttagg ataaaaaata
     1561 gtataaaatt ataaaaccat tttgaaagac tagagtatgt atatacttta tatgaatata
     1621 atattgaatt aatttatatt actggaattt ttaattccag taatattttt ttattatata
     1681 atttagcttt attaaaagtt tttattatta aaaatagctt atttatcgta aagtgaatga
     1741 tattgggctt ttaattatta tgaatgttag tatttaattt aaagacttaa ataaatttgc
     1801 catttctagc gcattcatag cacaatcata acctttattt ccagcttttg tacctgctct
     1861 ttcaatagct tgttcaatat tttctgtagt tacgattcca aatataacag gtaattcact
     1921 gtctaaagat actttggcta tccctttaga gacttcacta catacataat cataatgaga
     1981 agtagcccct cttataacac agcctaaaca gattatagca tcatacttac cacttttagc
     2041 cattttttga gcaacaagag gaatctcaaa agctccaggt acccaaacta tttctatatt
     2101 ttctggagaa acgtcatgtc ttaaaagaca gtcttcagct cctgataaaa gttttgatgt
     2161 tataaattca ttaaaacgag aatttattat acctattttt aaatcttttc caataagttt
     2221 tccttcatat atcattttta tttcctccaa ttttatttat gttatagatt tatatttata
     2281 aatatcttta atttaattat aaaaaactac ttagtagaaa aatatcatca tataatcatt
     2341 tatataatat ctaaaagatg tcccatttta tcttttttag tttttaaata tagcttatta
     2401 aagtcattaa tttcttcatt aatagggatt ctattttcga tttttattcc atatttctct
     2461 aattgattta ttttatctgg gttattactt aaaagattta tactttttat gtttaaattt
     2521 tttaatattt gagcagccat atagaaatct ctcatatctt cttcaaatcc aagcattaaa
     2581 tttgcttcaa cagtatcgta accttcttct tgaagtttat aagccttaat tttatttaaa
     2641 agaccaatac ctctaccttc ttgcttcata taaattaaaa ctccacttcc attttccaca
     2701 attttcttca tagaagattc tagctgtaat ccacaatcac attttagaga gtggaacaca
     2761 tctcctgtta aacattcaga atgaagtcta actagagtat tttctatatt tatatttcca
     2821 taagtaaggg caatgtgttc ttcatttgaa taagtatctc tatatcctat gatttcaaaa
     2881 tttccatatt ttgtcggaag gaaagcacta gatacttttt ctatagtagt ttcatttatt
     2941 ttgcggtatt ctataaggtc ttttatagtg atgattttta aattatgctt ttctttgaaa
     3001 atcattaaat catcaactct tgccattgta ccatcatctt tcattatttc acagataaga
     3061 ccaatctctt taaaacctgc aagtctagca aggtctactg aggcttctgt atgtccatcc
     3121 ctgacaagaa ctccaccagt ttttgctatt aaaggaaaga tgtgaccagg cgttttgaaa
     3181 tctttacttg tagaattttc atcacagaat aattttacag tttcagctct ttcatatgca
     3241 gatataccag ttagagtatc tgctccatct atagtaacag taaaggctgt ttgaaatgta
     3301 tctgtatttt ctctaaccat aagaggtata ttaagacttt taaatttttt ttcagtggca
     3361 ggtagacaaa ttagacctct accatatgta gccataaaat ttattgattc aggagtagcc
     3421 atttcagctg ccatcaataa atctccttca ttctctctac tttcatcatc aactacgatt
     3481 accattttcc cattttttat atcttcaata gcttcttcaa tagtattaaa catgtaattc
     3541 actcctttat tatttttaaa aaccattttt aaataaaaaa tctttatcta tatttgattt
     3601 atggttacta ctattagaat ttaattcctt gtagttatta gccataaaat tattaacata
     3661 ctttccaatt acatcgcttt ctaaattaac gaaatctcca acattctttg tcaagagaat
     3721 agtgttaatt ttagtatgag gtataataga aaccttaaat atttcatcat ctaaatatga
     3781 tatagttaaa cttacaccat caatagcaac agaacctttg agtatcattg aggataaaag
     3841 ttttttatca ggtcgtatac ttactaaaac tgcattttca tctttttcaa atttgcagat
     3901 agttccttta ccatcaacat gacctgttac tatatgacca ccaaatcttg aagaaagact
     3961 catagctctt tcaagattta ccttgtcatt tgcatttaat aaacctaaat ttgtggaacg
     4021 aattgtctcc atcataacat cggctgtaaa ttcatttttt ccgaggtttg aaacagttag
     4081 acaaactcca tttacggcta tactatctcc aagatttgtg ccatctaata ttttatttga
     4141 tagtatggtt acttttccac tcttaccatt agcagtaatt tttctaagta ttccaacttc
     4201 ttctactatg ccagtaaaca tcctaacctc ctatatgaat gtattaacaa aaatttaatt
     4261 taaaacatct gattctataa gaatatcgcc atctatcaaa gttacattat tgattgttaa
     4321 ctgtgttgaa tctgacaaat gatttattcc ttctccagaa acgaatgtag gtgcatcttt
     4381 accacctata atcttgggtg atagaaataa tttgacttta tcaactaact tatttctaaa
     4441 gagactgtca ttgagagtag caccaccttc aactagaaca gaatcaatgt ttaactctcc
     4501 taatttatac attacaaact ccaaatctac taagttgttt tttgaaggag aaattattgt
     4561 ttcaacatta ttttctttta acatagataa ttttatactt tctttgcaac atgtgaaaac
     4621 tatagtttta ctggttttat ctttaaccaa attactatta agtggcaact ttaggtgtgt
     4681 atctattact attcttgtag gatgagacac tttttcttga ttgagcctac aagttagtaa
     4741 aggattatcg ttcaaaactg tatttatgcc aaccattata ctttggtatt tatttctgta
     4801 tttatgagtt agataccttg atgattcatt agatatccat tttgattcta gtgattttgt
     4861 ggcaatttta ccatctagac ttactgctga ttttacaata caaagaggtc ttttgttttt
     4921 tatatgataa aaaaatgcct catttaaatc tcttgcttca tcttctaata ttcccacagt
     4981 aacatcaata ttgttatctt ttaatttttt tactccatta ccacaaacaa gtggatttgg
     5041 gtctaatgta gatattacaa ctctcttaat cttattttgt ataattttat ctacacaagg
     5101 aggcgttttc ccataatgag aacatggttc taagtttaca taaagagtag agtcttttag
     5161 actttgttta gcactgttta tagcatttac ttcagcatga ttagagccaa atttctcatg
     5221 atatcctttg cctattatat tactatcttt aacaattaca cacccaacta atggatttgg
     5281 atttacaaag ccttctccat ttttagccaa ttcaatagct tttttcatat aataaatatc
     5341 tttttctttt tgattcacaa aattcacaat atgtacacct cctgtttaat tggataattt
     5401 ttaaacaaaa aaccctgaga attaactcag ggtttagaat aatctacaat aaatgtttaa
     5461 taaatgtaga acaaaattgc tctacaaaaa cactcattaa atatcttctt ccatccagac
     5521 tttactgtcg gctttggaat ttaaccaaat caaccaagtt ttacattggc tcgcgggcta
     5581 taccgccgat tgggaatttc accctacccc gaagattaag tattaaattt atatttagaa
     5641 tgtatcataa attattttac tttgcaaact atttttttaa aaaatatatg ttaatatata
     5701 atatagaatg tctataaact ttgaaatacc acgattgtga atataaaaat aaaaatttga
     5761 acataatcag gaaagaagtc taattaattt aaattaggag agtaatatat gaataaaaaa
     5821 cttttagaaa tactatcaaa atactatgga tatacaagtt ttagaaaagg tcaggaatct
     5881 ataataaatt ctatcttaag cgaaaaagat gtgctagcta ttatgccaac aggaggggga
     5941 aaatcaatat gttatcaaat tccagctttg attttagatg gaatgacaat agtaatttct
     6001 ccacttatat cacttatgaa agaccaagta gatgccttaa agactatggg aattagtgct
     6061 gcttttataa atagttcatt aagcagcaaa gaatttaatg aaatattaaa taatattaga
     6121 aaaaataatt ataaaatact ctatattgct ccagagagat tagatgcaca agagtttatt
     6181 gagctaataa ataataacaa tgtaagtcaa gttgcgatag atgaagcaca ttgtgtatct
     6241 caatgggggc atgattttag gttgagttat agaaggattt ctgattttat aaaaaatttg
     6301 cctaaaagac ctatagttac agcatttact gcaacagctt cagaagaggt aagaactgat
     6361 ataataaatt tactgtgttt agaaaatcca gattattata taactggatt tgatagagag
     6421 aatttatcaa taaatatagt aaaatcatct agtaaaaata agtatatttt agattatatt
     6481 caaaatcata aaaatgagtc tggaattata tatgttgcaa ctagaaagga agttgaaaat
     6541 atatataatg gtttatctaa gagaaatata tctgtatcaa aatatcatgc aggtttatct
     6601 aaaaatgaaa gaagtaaaaa tcaagaagat tttataaatg ataatgtgga tataatggta
     6661 gcaacaaatg catttggaat gggtattgat aaacctaata taagatgggt tatacattac
     6721 aatatgcctc aaagtataga aaattactat caagaaatag gtagagctgg tagagatgga
     6781 gaaaaaagtg agtgtgtact tttattttct ccaggagatg tacatataca aaaatattta
     6841 attgatattg gagttgaaaa tcctgaaaga aaattatttc agcataagaa gcttcaatac
     6901 atgattgact tagtttacag taattcatgc tatagaaaga caatattgag ttattttgga
     6961 gaaaattata tagacaattg caataattgt agcaattgtt tagtagaggg tgaaatagta
     7021 gataaaacta tagatgcaca aaaagtcatt tcatgtgtag ctagaatgaa aagaagttat
     7081 ggtgttacta ctattgtaga tgtgcttaga ggttctaaga ataaaaagat tttacagctt
     7141 ggattaaata ctttgtctac atataacatt atgagagatt attctagtga agacttaaag
     7201 aattttataa atacattggt ttctcatggt tttttagatt tagttgagac tctaggcaat
     7261 ggaaatagag gtagttttcc tactataaga ttaaatgaga tgtctatgaa agttttaaaa
     7321 ggtgaagtga aagtagagtt taaagaaatt gttatgacaa aatcattgga agtagaggat
     7381 gagttatata atgctttaag agaacttaga cattcaattg caagtgaaga aaggatagct
     7441 ccatatatgg tatttggaga tggtacactt agagccatgt ctagtagtta tccaattaat
     7501 aaagaagaaa tgctagatat ctctggagta ggagaaatta aatatcaaaa atatggtaga
     7561 gattttgaag cagcaattaa agaatatgtc gaaaaaaata atataaataa aaaaatagat
     7621 gaaaaaaatg tcgattcaaa gaacgttaat agtgatttct tagaggttaa tacagataaa
     7681 gttttatatg aaaaactgtt agtcattaga gaagaatatg caacaaagga aaaattacct
     7741 gcatatatga ttttagccaa taaggctctg aaagaaataa gtggaagata tccacttgat
     7801 gaagaacaat taaaagatat ttctggcata ggtggagtaa aatttgaaaa atatggagct
     7861 agtattttgg cagaggttaa taaatatgta aaagaaaata atattaatgt tatttgggag
     7921 aaaaagggca aaaggaagtt aatattagat ggagaaagta gaaaaaataa tgaaatagca
     7981 ttagatttgc taaatcaagg aaaagatata caaagtatca gtcaagaaat agaagtttca
     8041 ctgtcaacca ttattggata tgtgcatgac tatgtaaagg atggacatag tatatcattt
     8101 gaattaggac tagaaaattt ttataatgaa gataaaaaga agatgatttt agaagtttgt
     8161 gaaaaagttg gctatgataa tttaaataac ataaaaagaa aacttccaga ttcaataaag
     8221 tatgaaaata taagagctgt gatacttgac tcttatcttg aaaacttaaa aaataatatt
     8281 atagcagagt aatttttaac ttaataaaaa ataaaatttg tattattgtg ttgaactaat
     8341 aattttgctg tgttatactg aatttgtaaa aataatgaaa aattagagct aggggcgcta
     8401 gaattggcta gctgagagat aaagccgtaa cttacaaacc ctaataacct gatcaagata
     8461 atgcttgcga agggaagctt tttaatataa ttttattata taaataggca aattattcaa
     8521 tgttaggaga aatttgtcta agtgtatata cgattataag agtgctttcc aaacgaggaa
     8581 aagcactttt tttattttca aaaactataa ctttaatctt ggaggattgt aatatgaact
     8641 atacaacaca aatggatgct gctagaaaag gcataataac taaagaaatg gaaatcgttt
     8701 ctcaaaaaga acaggtagat gtaaatgaat taagagaatt aatagcaaat ggacaagttg
     8761 ttataccagc taataaaaat cataaatctt taagtgcaga aggtgtaggt aaaaatttaa
     8821 gaacaaaaat aaatgtaaat ctaggaattt caagagattg taaggatata gaaaaagaac
     8881 ttgaaaaagt tagagtagca atagacatga aagctgaagc tataatggat ttaagtaatt
     8941 atggcaaaac tagagaattt agagaaaagg ttgttgaaat gtcacctgca atgataggtt
     9001 cagtacctat gtatgatgca gtaggatatt tggaaaaaga attaaaagat ataacagaag
     9061 aagagttttt aaatgtaata agacaacatg ctattgatgg agtagacttt attactatac
     9121 atgcaggtct tacaagaagt gtttgccaaa aaataaaaaa tcatgagaga ttgactcata
     9181 tagtatctcg tggaggttct ttattgtttg catggatgga attaaataat aaggaaaatc
     9241 ctatttatac taattttgat aaaatattgg atatatgtga agaatatgat gttacattga
     9301 gtttaggaga tgcttgtaga ccaggttgta taaaagattc tactgatggt gttcaaattc
     9361 aagaacttgt agtattaggt gaacttacta aaagagcatg ggaaagaaat gtacaagtaa
     9421 tgatagaagg tcctggacac atggctattg atgaaataga agcaaatgta gtattagaaa
     9481 agagattatg ccatggagca cctttttatg ttcttggacc attggttaca gatatagcac
     9541 caggttatga ccatataaca agtgcaatag gaggagcttt agcatgtgct aaaggagtag
     9601 attttttatg ttatgtaact ccagcagaac atttaagatt gcctaattta gatgatatga
     9661 aagagggtat aatagctgca aagatagctg ctcatgcagg agatatagct aaaaatgtta
     9721 aaggtgctcg tgaatgggat aataagatga gtaaagctag agctgattta gactggtgtg
     9781 agatgtttag acttgcaata gaccctgaaa aagctaagag atacagagat gaatcaactc
     9841 ctactcatga ggatagttgt actatgtgtg gaaaaatgtg ctcaatgaga acagttaaga
     9901 aaatattaaa caatgaggaa cttaatctaa tataattttt ggctagtatg actggaataa
     9961 aaagaagctg aaaagaggag gtgatttagt gaaggttaat gggaaggaaa ttgaatttga
    10021 aaaagatttg actgttatag atttattaaa taaatataat ttaaaaagtg atagagttgt
    10081 agttgaagtg aatttagaga taattgaaga atctaactac aatacatatg tattaaaaga
    10141 cgaggacatt gtagagctta ttagctttat tggaggtggt taaaataaaa atatttgtaa
    10201 atgaattatt aacagatgtt gaggaaaata taactgctta taaagttaga gatagctata
    10261 acaataaatg tgatgtattg gtgttaaatg gatatccaat taaaacagat atgccccttt
    10321 gtgaaaatga taaattaaca cttatacaaa aaggagttaa gccatcactt gatgaattgg
    10381 aaagcttgtt gattgctaga catactccaa atatacataa taaattaaaa aaagggaaag
    10441 ttgctatatt gggattgggg ggacttggtt ccaatatagc tatctcttta gctagaatag
    10501 gagtgggaga acttttactt atagattatg atgttgtaga accatctaat ttaaatagac
    10561 agcagtattt tatagatgat ataggaaaac taaaaactga tgccatgata gaaaatataa
    10621 aaaaaataaa tccatttata aaattaaata aacgagatat ttttttaaac aagaacaata
    10681 tggatactat taaggattca gatttaataa ttgaggcctt tgatgatgct tcatgtaaag
    10741 cacaggtatg taattatgta ttaataaatt taaaagataa atatttaata gcatcatctg
    10801 gtatggcagg ttactatgat tcaaatataa taactactaa gaagataaaa gacaggtttt
    10861 atatatgtgg ggattttgtg aatgaagcta aatttggtga agggcttatg gctccaaggg
    10921 ttgccatctg cgcaaatcat atggcaaatt tggcaacgca aatacttata gatatgtaaa
    10981 tattaaaatt agatataaaa aagattgaat attaaaaaaa tttaacgtgg agggaaataa
    11041 tatggataaa ttgatacttg gtggacatga atttaatagc agattattgg ttggaacagg
    11101 taaatatggt tcaaataata tattgcctga ggtaataaaa gaaagtggaa gtgaaataat
    11161 aacaatggca cttagaagag tggatttaga caataaacaa gaaaacatat taacgtatat
    11221 tccaaaagag atgacaatac ttccaaatac atcaggagct actaatgcag aagaagctgt
    11281 aagaatagct agaatatcta gaaaaatggg atgtggagat tttataaaaa tagaagtaat
    11341 atcagatact agatatttac ttcctgataa tgaagaaact ataaaagcta caaagatact
    11401 tgctgatgag gggtttatag ttcttccata tatgacacca gacctttatg ctggaagaag
    11461 acttatagaa gctaatgcag cggcagttat gccacttgga gctccaattg gttcaaatag
    11521 aggtcttcaa atgaaagaaa tgataagaat aatgatagat gagttggata taccaataat
    11581 agtagatgca ggtattggaa aaccatctca agctatggag gctatggaaa tgggagctga
    11641 tgcagtactt gtcaacactg ctatagcttc agcaggagac cctgtacaaa tggctagagc
    11701 atttaaatta gctgtagaag gtggaagaga agcatatatt gcaaaaacag gaaatgtgtc
    11761 agaatttgca aatgcatctt ctcctttaac aggtttttta ggcaatttat agaaagtggt
    11821 gattggtgat gagtttttat gatgtaatag aaaaatatag ggattttgat tttgatggat
    11881 atttaaataa tgttactgat aatgatgttt taagaagttt atcaaaagac aagcttgaag
    11941 attttgatat attaaatttg ctttctaaaa ctgcagtaaa acatttagaa gatatggcac
    12001 aaaaagcaca taaattaagt gttcaatact ttggtaaaac agtatgttta tatacaccaa
    12061 tgtatatagc aaattattgt gttaatcaat gtgtttattg tagctataat ataaagagtg
    12121 gaataaaaag aaaaaaatta actatggatg aaattagaga agagggagaa gcaatttcaa
    12181 aagaaggttt caaacatcta cttgttttga ctggagaaag tagttttcac tcaagtgtag
    12241 aatatatagg tgaggctata gaaatattaa gagagaaatt tccctctata ggtatagaag
    12301 tttatccaat ggaagtagaa gaatataagt acattgtaga taaaggtgtt gaaggattaa
    12361 cagtatatca agaaacttat gacgaggaaa tatataagag agtacatata aaaggcccaa
    12421 aatcaaatta taaatttaga ctagatgctc ctgaaagagg ggcaaaagca ggtatgagga
    12481 ctttatcaat aggtgcactt ttagggctaa atgattttag aaaagaaact ttttttacaa
    12541 tattgcatgg gaaatactta aaaacgaaat atcctcatat tgagctttca tattcaacac
    12601 caagaatgag accttttaaa gggtgttttg aggaattggt agatataagt gatactgatt
    12661 tagttcaagc tatggtatgt atgagattat ttgaccctca tgcagctata aacatatcca
    12721 ctagagaaaa tttagaaatg agaagtcata taataccttt aggagtaact aaattgagtg
    12781 caggtgtatc tactgatgta ggaggtcatt ctcaagatga acatgatact gctcaattta
    12841 agataaatga tgaaagtact gttaaagatg tggagaaaat gctaaactca attggttatc
    12901 agcatgtgtt taaagattgg gaaagatttt aaatgtatct gataacaaac agaaaattat
    12961 gtagtgagga acgatattta gaagttatta aagagtctat attgagtggt gtagaaaata
    13021 taataataag agaaaaggat ttagaatatc aagagctaag aaaattatat atgaaaataa
    13081 aaactaaaat caattgtata gattttcaag agcaaatatc agatgaaagt ttgaaaacta
    13141 atataaatca aaaagagttt agaaataaat tcaaggttaa ttttataata aatagtaaca
    13201 ttgaattttt tgaaaaagtg gattgtcaag gtatccatct tccttttaaa ttattcttga
    13261 atttaattga aaataagtat aattttaatg aaaataaaat actaggatta tctttacata
    13321 aagtagagga agtagattat ttagaaaaat taataagaaa tcaaaatata aaaatagatt
    13381 acataacatt atcacatata tatgaaacta aatgtaaaga aggattaaat ccaaaaggaa
    13441 ttgagctttt aaaagaagct aaaaagatta ctgatattaa aataattgca cttgggggaa
    13501 ttttaccatc taatgtcaag gaaacattaa aatactgtga tgattttgct ataatgtcaa
    13561 ctataatgag gtctaaagat attaaaaaaa ccatatcaaa ttataatgaa aagttgaatt
    13621 agtaaatata gtatattgaa tttttaactt aaataaaaat aaaaaagtta tcttttaaat
    13681 tttaaaaggt agctttttta ttttatatct ttgctaataa aaaattgtaa aaagggaaaa
    13741 ctttagtcag agagattaaa caatatccta gaaagattta aaatttagta aagtatggag
    13801 gacattataa tgactgacag taaaaagaaa cgatttatta taccacacac ttttacaata
    13861 atatttttac taatagtctt gatggcaata ttgacttgga tagtaccaag tggtgaattt
    13921 agtagagaag atgtagaagg tagaatggta gttgtaccag ggacttatca aagtgtagaa
    13981 agtaatcctc aaggatttgc agatgttttt aaagcaccaa tagaaggctt tatcgattca
    14041 gctgaagttg taggttttgt tttaatagtt ggaggtgctt ttggtattgt aaataggact
    14101 ggagctatag aagcaggaat agcttcggtt atctctaagt ttaagggaaa agaacttctt
    14161 ataattccaa tatcaatgat tttatttgga cttggaggta caacatttgg gatggcagaa
    14221 gagacattac cattttatat gatatttgtt ccactcatga catccttggg atatgattct
    14281 ctaacagcaa tagcaattgt atttatagga gcagcagcag gagcagccgc ttcaacaata
    14341 aatccatttt cagttggtat tgcacaggca ctagctcaac ttgctcctgg ttcaggagta
    14401 acttacagag tagttatttt tatagcatat atactaataa gtatagcatt tgttatgtac
    14461 tatgctaaga aggtaaagga aaatcctgaa agttcaatag tatatgaaat agataaaaat
    14521 aataaatcaa tacttaatca aacttcaaca gaaataaaag aatttacttt taaagaagta
    14581 tctgttcttg ctatatttgg aatagggatg gcaataatga tttggggtgt tttaagtcag
    14641 ggatggtaca ttccagaaat atcaatgtgt tttgctgcaa taggtgtgct ttctggattg
    14701 gttggtagat tatctcaaat tgaaatctca gaaagtttta tagatggagc aaaagattta
    14761 gcatctgcag ctcttgctat agctttggct cgtggaatcg taataattgc tcaaaatgga
    14821 tttataatag atactatatt aaattccgca gcagcctttc taggtgggct tccaaaggtt
    14881 atatttgtat atttatcatt tttcttggaa gctgcattgg catttttaat tccatcatct
    14941 tcaggtcttg cttcacttac agtacctgta cttgctcctc ttggtgattt ggttaatata
    15001 tcggctcaag tgatagtaac cgcttatcaa tttggtgtgg gtcttacaaa ctttataact
    15061 ccaacttcag gagtactgat gggagcactt gcagtagccc atattccatt ttcaaaatgg
    15121 gtaagattta taatgcctat cttgttgatt ttgacagctg tatctctagt ctttttaaca
    15181 ataggtattt atatagggtt ttaattaagt gtagttttat ttaagatatt tagtaatggt
    15241 ataaaatgat aatatgtttt caataaattg ccactaattt aattagtggt aatttgtttt
    15301 ttgtatttaa aaataaatgt atttacttgt attttgaatt aatatctaca tagacattgt
    15361 tttaattgtt atattttcat ttaattaagc attgatttat cattttttat atttcatata
    15421 acaatgcaaa aaataatttt tatatagtaa atgacaaaag tttacaataa atgtatattt
    15481 tcttactcat tccttaaaat tactcattta gtttaataac tctcatttca tatgtaaagt
    15541 tggtaaaaaa attaaaatta aaagtaaaaa actaaataaa ttaatgttaa tttgaaatat
    15601 atatgaaggt ttttggagaa tacttactta tgataggaaa aaatgttaaa ataatagtgt
    15661 aatcaaatat aaaggactga aataattaac agttattaaa tattaggagt gtaaaaattt
    15721 atgggattaa aagaatttga ttttattgaa gagtctattg atatgttgag gacaatgtca
    15781 ccaacattag aaactatatc agatgaaata gaagagtatt ttgaaaatat cttggatgaa
    15841 aagaatcaag aatatataaa tgtaacctct agaataaaat cagaatcaag tttaagagaa
    15901 aagataatta gaaatagata tttaaaaaaa tatggagaag caagtaatct tattcataat
    15961 gtttctgact taataggcct aagaattgag tgtagattta ttgaggatga aaacaaaata
    16021 tatagacttt tgagaagata ttttaataaa acagatgaca aaataaacta ttataataaa
    16081 gagaataaga atattaaatt aaaactatct gagaggcaac ccaataaaca aaaaaatgga
    16141 tttgaaatat ataaaataga tggagttttt gcgtatttag atagagaagt aaaatttgaa
    16201 cttcaaatta aatctcttgt aaatgtgttt tggagtgaaa tagaacataa aataatttat
    16261 aaaaacaata catatttact tgctgataaa tttataaagg atatgatgga ctctataaag
    16321 aataatctta ctatgataga taatcagctt ttaagtattt ataaaaactt tcattcaggg
    16381 aagtctttta atatgaaagt aagtaaaaaa gaaattgaaa aattatttgc gaaattagtc
    16441 tatgacgctt tttctgaaaa gatgaataaa agtataggtt ttgttgtaga ttttaaaaaa
    16501 ccatgtgaga ctatattgaa ctattctttt aataaacaag atataagtga tgaagtttta
    16561 ggtaatttta tgcttgatga gtttgcaaga ttaaatgaaa ttgtaaacaa ggatatagat
    16621 tttaatgagc aaatagaatt tgaaagagaa ccaacatttg atgataagtt ttgtaaagac
    16681 ctaggaaatc attttagaag tagattaaac acagaatttc catggaacct attttttaga
    16741 atattatttg aaatagagcc atataacaat accaaagact ttgaaaactt tgtagagttt
    16801 ataaaagaaa atgtgctact agaagaaaat agggagcaat tattatgcca atttgaagaa
    16861 gatagcaaac ttataattga agatatatat gattgtatat ttaatagtat aagtgagatt
    16921 gatagtgttg aaattttata taactataat cttgaaaaaa taaactttac atcaagtgaa
    16981 atcataaatt gtatatgtag agaatatgag tgttatggtg aatacttaga agaaaaagaa
    17041 aagcttatga atacatttaa agaaaagatt attcaaatct ttgaataata ggttaatgct
    17101 gaagtggcgc taatgcgcca tttttcaaat atatatgaat taagtaaaat tattttggag
    17161 gaggcgattt gtatagagaa aacaggtgta attttggcag ggggaagaaa ttctagaatg
    17221 ggtagagata aagccttttt agagttacat gataagcttt ttattgaaat tgcaatagaa
    17281 gcatttaaaa actttgatga gttgataata atatctaata atgaagaatt atattctaaa
    17341 tacgatatta aagtttataa tgatatagta aaagatgttg gtccaattgg aggaatatat
    17401 actgctcttg aatatgcaaa gtatgatata gttacaattg catgtgatat gccatatcta
    17461 aataatcaaa tagtcgaaag aatagctaat aaaatgaatg ataaaagtgt gatttcagtg
    17521 acaaatggaa agttacaacc attgtgttct ggatataaaa agagtataat aaataaagta
    17581 tctttatgta taagggaaaa tgatttaaag ctcagaagct ttatagataa aatagataaa
    17641 agttatatat actttgatga agaagattta tttttaaatg taaacactgt tgatgagtat
    17701 gaaaaattaa ctaaagttta attagctatg gttgtaaaat agagtaggat ttatatggag
    17761 gagagtttat gaatttactt aaatgcgatt cttgggcagt aatattaaat aatagcgata
    17821 aagaaagtaa agcatataaa atattagatg aacttaaaag gaatatgtac aaagttgttg
    17881 ctatagatga agagaaaaaa cctattgaag gaatagatgt gtatgaatgt ttaaaagatg
    17941 ttccacacaa tattgatgtt gtagctatta ttgataaaca atctaagatg gatgtgattt
    18001 tagaagaagt agagcttttg gatatacaaa atatgtggtt tgaaaaagga agctttagtg
    18061 aaatgatgat taaaaagact aaagatttaa aattaaatat agaatataat ttaagtttat
    18121 atgatgagtt gactagataa aattatattt cttaataata aaaatataat tagttaataa
    18181 aacatattat tttatagtat agatcggtta ataaaagtac agattggtta atgaaacatt
    18241 aaattacaat atttgttaaa aaaattgtga gttacatgat ataatgtatt aaataggata
    18301 ctaaggagtt gatatattat gttaatagta actacagaaa aagtagaagg taaaaagata
    18361 tcaaaggttt taggattagt gagaggaagt acaataagag caaaacatgt tggaaaagat
    18421 ataggagcaa gttttaagaa tcttgttgga ggagaactta ctggatataa tgaaatgctc
    18481 actgaagcaa gacaaattgc cataggtaga atggttgaag atgcaaaagc taaaggtgca
    18541 aacgcagtaa tagcatttag actgtcttca gcttcagtta tgcaaggagc agcagaaatg
    18601 cttgcttatg gaacagcagt tgttttagaa gatgataata gtattcttga aaaataaaat
    18661 ataaatagtt aaaaagaggc atcttttaaa aattttatgg atgccttttt ttatttgaaa
    18721 aaactaattt gagaagaaat tttaactatt atgacaataa aattagggtg atattatata
    18781 aataagtaaa attatattat ataatgtatg gtatagactt taaaaatttt atttgtagag
    18841 aaaaatatgg acaatgttat aataattata gaaattaaaa gtacttacat tcattatgta
    18901 tgtgacatgt ataattagtt ttatatttaa tacagttttg aagtaatatc ttcattttga
    18961 gaacgttgga ataataaaaa atgtatgtat tataggtgat ataaataaaa aataaatata
    19021 atatgttata ttgctgatag aaaagagaat aaaagaaaat aggttttatt aaaagagatt
    19081 tttatttata ggacttaatc gatgtataga ggggtgagaa catatgttta atgttgcaat
    19141 tataacactt agtgataaag gatatgaagg aaaaagagaa gatataacag gaaaaaagtt
    19201 aactgaattt gttgaaaata caggagctta taaagttact gaatatgtac ttataaaaga
    19261 tgataaggaa atgctaaagg aaaatattat aagactttgt aatagtaata aaatagattt
    19321 aattcttaca aatggaggta ctggtttttc aaaaagagat ataaccccag aagcaactaa
    19381 ggaagtgttg gaaaaagaaa taccaggtct gagcgaatat atgagaatga aatccacaga
    19441 aattactaaa aaggccatac taagtagggg tgtgagtgga ataagaaata attctataat
    19501 aataaattta cctggaagtc ctaaaggtgc agttgaaaat ctaagtttta taattgatgt
    19561 tttagaccat ggcatagaag ttttaagagg agaagctaca gaatgtgcca ctaaaaaaag
    19621 tgaatagtat ataatctaga tagataaaaa atagacaaag aggtagataa agtatgattg
    19681 ataagtatgg aagaaaaata gactaccttc gtatttcact tacagataag tgtaatttaa
    19741 ggtgtgtcta ttgtatgcca ccagatgtaa aatttgataa aaattatata aatgaaaatc
    19801 taagctttga agactacaag tttattataa aggctatggc tgaacaaggt ataacaaaaa
    19861 ttagatttac tggaggagaa cctcttttat atcctaaatt aaatgagctt ataaaattta
    19921 caaaagaaga atgtggaata aataacatag gaatgaccac taatgctatt gggctttctg
    19981 atagaatctt tgagcttgaa aaatgtggct taaataaagt taatataagt ttagattctt
    20041 tgaaggaata taagtataaa tccgtaacaa gaggaggaaa cttaaaagat gtcttaaaat
    20101 cgattgaatc ttgtttaaac ttaggtataa aagtaaagtt aaattgcgtt gctataagtg
    20161 ggtttaatga tgatgagctt aaagatttta tgtttttaac agttaaatca ccaattgatg
    20221 taagatttat agagcttatg ccattaggtg aggctaatag agtttataag aagggttatt
    20281 ttaatgtaaa agaaatgatt gaaaaaatat atggtttata taaagtcaaa aatgatgaaa
    20341 aaagtacagc agaatattat atgtttaaag gagctaaagg aagaatagga attataactc
    20401 cattaagctg ttcattttgt aacacttgta atcgtattag acttacttct agtggtgcaa
    20461 taaaattatg tctacattca aaagaagaaa tagatataaa accattttta cataaaccat
    20521 tgttatttag agaatctatg aaagatataa taaaacaaaa accagaaaaa catcatttac
    20581 tagaaaataa atgtagtgat acaaataggc gtatgtatga aattggagga taagtaatgt
    20641 taacacatat aaatgaaaaa gggtatgcca agatggtgga cataagtgaa aaagatgata
    20701 ctaaaagaac ggccgtagct acagctacaa ttactcttag taaggaagca ttagaaaaag
    20761 taaaaaatgg tcagataaaa aaaggagacg tattgtctgt agctcaagtt gcaggtataa
    20821 tgggagctaa aaatacatct tcaaacatac caatgtgcca tcagattaaa ttagttggat
    20881 gtgatttaga atttgatgta gatgattcta tgtctgctat taagatatac gcaacctgta
    20941 aatctcttgg gaaaactgga gtagaaatgg aagctttaaa tgcatgttct ttagcagcac
    21001 ttacaattta tgatatgtgt aaagcagttg ataaaaaaat ggttataagt aatatccatc
    21061 ttgtagagaa gactggtgga aaatcaggag attttaagtt cgagtaaatt aataatatat
    21121 tgggttaaaa tttggaggaa atatggcgaa ggtagtgtca ataaatataa gtgagaaaaa
    21181 aggtgtaatt aaagttcctg tacaatgtgc agagctaaaa ataaatcatg ggatagttgg
    21241 agatgcacat gcaggaaact ggcatcgtca gataagctta cttggaaaag aaagcataga
    21301 taaaatgaaa atgaaaggct ttgaccaatt aaaatatgga gattttgctg aaaatgtaac
    21361 tacagaaggg atagaagttt tttccctgcc tgttggtaca aagttaagaa tagggcaatg
    21421 tgaagttgaa gtaactcaaa tagggaaaaa atgtcacaat ggatgtgaaa ttaagaaatt
    21481 gacaggtgac tgtgtgatgc cacgagaagg aatttttgta aaggttctaa aagaaggaat
    21541 tataaatgtg aatgattcaa tagatgtaat ctaatgaagt gactattaaa atataattat
    21601 aag
//
LOCUS       DAMJXI010000061        21491 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.063, whole genome shotgun sequence.
ACCESSION   DAMJXI010000061 DAMJXI010000000
VERSION     DAMJXI010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21491
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.063"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            <1..639
                     /gene="tuf"
                     /locus_tag="PC465_002864"
     CDS             <1..639
                     /gene="tuf"
                     /locus_tag="PC465_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDF2650149.1"
                     /translation="EWGDKIVELFEQIDEYIPAPERDTDKPFLMPVEDVFSITGRGTV
                     ATGRVERGVLKVQDEVELVGLTEAPRKVVVTGVEMFRKLLDQAQAGDNIGALLRGVQR
                     NEIERGQVLAKTGSVKAHTKFTAEVYVLKKEEGGRHTPFFDGYRPQFYFRTTDVTGAC
                     KLPEGIEMVMPGDNVTMEVDLINSIVVEEGLRFSIREGGRTVASGVVATIIE"
     gene            1011..1322
                     /gene="rpsJ"
                     /locus_tag="PC465_002865"
     CDS             1011..1322
                     /gene="rpsJ"
                     /locus_tag="PC465_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HDF2650150.1"
                     /translation="MAKNEKIRIRLKSYDHKLLDFSAGKIVETAKKAGSQVSGPVPLP
                     TEKQVVTILRAVHKYKDSREQFEIRTHKRLIDIANPTPKTVDSLMRLDLPAGVDIEIK
                     L"
     gene            1414..2043
                     /gene="rplC"
                     /locus_tag="PC465_002866"
     CDS             1414..2043
                     /gene="rplC"
                     /locus_tag="PC465_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HDF2650151.1"
                     /translation="MKGILGKKVGMTQIFTDKGVVIPVTAVEAGPMVVTQIKTVDKDG
                     YNAIQIGFEDAKEKALNKPKKGHLAAANVLKKHLKEFRVDSVEGYTVGQEIKADVFEA
                     GAKIDVTGISKGKGFQGPIKRHGQSRGPETHGSRYHRRPGSMGACSYPGRVFKNKKLA
                     GHMGSVKVTVQNLEVVKVDADKNLILVKGAIPGAKGSVVTIKEAIKVSK"
     gene            2073..2696
                     /gene="rplD"
                     /locus_tag="PC465_002867"
     CDS             2073..2696
                     /gene="rplD"
                     /locus_tag="PC465_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001127258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HDF2650152.1"
                     /translation="MPKLNVLNVSGQNVGEIELSDSIFGVEVNGHVLYEVVKNQLANK
                     RQGTQSAKTRAEVRGGGRKPWKQKGTSRARQGSTRSVQWVGGGVAFAPKPRSYKYTLP
                     KKVRRLAMKSALSSKVQNSEVIVLDALNMDAPKTKEFAQILNNINAAKKALVVIADKN
                     DNVIKSARNIEGVQTALVNTMNVYDILKYDSFIITTDAVKKVEEVYA"
     gene            2696..2986
                     /gene="rplW"
                     /locus_tag="PC465_002868"
     CDS             2696..2986
                     /gene="rplW"
                     /locus_tag="PC465_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HDF2650153.1"
                     /translation="MTNPHDVIIRPVVTEHSMAEMGEKKYTFVVAKDANKTEIKKAVE
                     KVFGVSVDKVNTLNYDGKVKRMGRTQGRTSSFKKAVVKLTADSKEIEFFQGM"
     gene            3016..3846
                     /gene="rplB"
                     /locus_tag="PC465_002869"
     CDS             3016..3846
                     /gene="rplB"
                     /locus_tag="PC465_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HDF2650154.1"
                     /translation="MAIKKFRPTSPALRQMTVLVSDEITCNQPEKSLLVNLKKNAGRN
                     VHGRITVRHRGGGQKRKYRIIDFKRDKDGIPAKVATIEYDPNRTANIALLNYADGEKR
                     YILAPVGINVGDTILSGLGADIKPGNCLALKDMPVGTIIHNIELKPGKGAQLVRSAGV
                     SAQLMAKEGKNALLRLPSGEMRLVSINCKATIGQVGNIEHGNVVIGKAGRKRHMGIRP
                     TVRGSVMNPNDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKKNKASNKLIVSRRTK
                     "
     gene            3881..4162
                     /gene="rpsS"
                     /locus_tag="PC465_002870"
     CDS             3881..4162
                     /gene="rpsS"
                     /locus_tag="PC465_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HDF2650155.1"
                     /translation="MSRSTKKGPFVHARLLKKIEAMNASGNKEVIKTWSRSSTVFPQM
                     VENTIAVHDGRKHVPVYITEDMVGHKLGEFVPTRTFKGHKDDEKSNKRK"
     gene            4194..4529
                     /gene="rplV"
                     /locus_tag="PC465_002871"
     CDS             4194..4529
                     /gene="rplV"
                     /locus_tag="PC465_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HDF2650156.1"
                     /translation="MEAKATAKYVRVSPRKAGQICDLVRGKNVDEALAILKFTPRGAA
                     SIIAKVVKSAKANAENNHEMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSH
                     IEVVVKEKK"
     gene            4552..5367
                     /gene="rpsC"
                     /locus_tag="PC465_002872"
     CDS             4552..5367
                     /gene="rpsC"
                     /locus_tag="PC465_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HDF2650157.1"
                     /translation="MGQKVNPHGLRVGVIKDWDSRWFATDKKEFGNLLLEDHNIRKFL
                     KKRLYSAGVAKIEIERSANKIKMDLHVAKPGVVIGRAGAGIEALKAELEKMTKKTIIV
                     NIVEVRSTDKNAQLVAENIALAIERRVAFRRAMKQAIQRAMKSGAKGIKVSASGRLGG
                     AEMARTEGYSEGNVPLQTLRADIDYGFAEADTTYGKIGIKVWICNGEVLPTRDGVNPR
                     EESRKSDRRDNKRDNRRNDRRGNDRRGNDNRGNYRGQRPQGGSRPQRTENKGN"
     gene            5403..5834
                     /gene="rplP"
                     /locus_tag="PC465_002873"
     CDS             5403..5834
                     /gene="rplP"
                     /locus_tag="PC465_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HDF2650158.1"
                     /translation="MLMPKRVKRRRVHRGSMAGQAHKGNKVTYGEFGLVALEASWITS
                     NQIEAARIAMTRYIKRGGKVWIKIFPHKPVTRKPAETRMGAGKGSPEYWVAVVKPGRV
                     MFELAGVSEDKAREAMRLAAHKLPIKCKFVKKEDLEVKGGE"
     gene            5836..6039
                     /gene="rpmC"
                     /locus_tag="PC465_002874"
     CDS             5836..6039
                     /gene="rpmC"
                     /locus_tag="PC465_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HDF2650159.1"
                     /translation="MKAKELRDLTSEELMNKLNDFKSELFSLRFQLATGQLENTARIK
                     FVKKDIAKVKTVLAERKLYETRA"
     gene            6063..6317
                     /gene="rpsQ"
                     /locus_tag="PC465_002875"
     CDS             6063..6317
                     /gene="rpsQ"
                     /locus_tag="PC465_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HDF2650160.1"
                     /translation="MERGRRKVRIGRVVSDKMDKTIVVAVEEFVRHPLYNKRVKRTKK
                     FKAHDEKNICNIGDRVKIMETRPLSKDKRFRLVEVVEKVK"
     gene            6343..6711
                     /gene="rplN"
                     /locus_tag="PC465_002876"
     CDS             6343..6711
                     /gene="rplN"
                     /locus_tag="PC465_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007885948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HDF2650161.1"
                     /translation="MIQQESRLRVADNSGAKELLCIRVLGGSKRRYGNIGDVIVATVK
                     SATPGGVVKKGKVVKAVIVRSKQGVRRNDGSYISFDENAAVIIKDDKTPVGTRIFGPV
                     ARELRDNEFMKIVSLAPEVL"
     gene            6735..7040
                     /gene="rplX"
                     /locus_tag="PC465_002877"
     CDS             6735..7040
                     /gene="rplX"
                     /locus_tag="PC465_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HDF2650162.1"
                     /translation="MRVKKGDTVVVIAGKDKGKKGSVLKVYPKTSKVLVEGVNVITKH
                     QKPSAMNQQGGIINKEAPIHISNVMPFDPETGKGVRVRYEVKDGNKVRVSAKSGKEL"
     gene            7070..7612
                     /gene="rplE"
                     /locus_tag="PC465_002878"
     CDS             7070..7612
                     /gene="rplE"
                     /locus_tag="PC465_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HDF2650163.1"
                     /translation="MASRLQEKYMKEVAPALMEKFGYKNVMEIPKLNKIVINMGIGDA
                     RENPKGLEKGVEELEMISGQKPVITKARKSVANFKLREGMPIGTKVTLRADKMFYFMD
                     KLVSVSLPRVRDFRGVNPNAFDGRGNYALGVKEQLIFPEIEYDKIDKVRGMDIIFVTT
                     AKTDEEARELLKLLGMPFSK"
     gene            7630..7815
                     /locus_tag="PC465_002879"
     CDS             7630..7815
                     /locus_tag="PC465_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HDF2650164.1"
                     /translation="MARKAMVVKQQRKQKYATREYTRCTICGRPHSVLKKFGICRICF
                     RELAYKGQIPGVRKASW"
     gene            7848..8246
                     /gene="rpsH"
                     /locus_tag="PC465_002880"
     CDS             7848..8246
                     /gene="rpsH"
                     /locus_tag="PC465_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HDF2650165.1"
                     /translation="MTMTDPIADMLTRIRNANVVKHETVDVPASNMKKELARILLEEG
                     FIRGYDVIEDGKQGIIRIQLKYGQEGERVITGLKKISKPGMRVYAANHEIPKVLNGLG
                     ISVISTSKGILTDKQARKENVGGEVICYVW"
     gene            8277..8819
                     /gene="rplF"
                     /locus_tag="PC465_002881"
     CDS             8277..8819
                     /gene="rplF"
                     /locus_tag="PC465_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HDF2650166.1"
                     /translation="MSRIGVKPIIIPAGVEVTIAEGNLVTVKGPKGTLTKQLSAELNI
                     KKEENTIMVERPTDNKKHRSLHGLTRTLLDNMVVGVNTGFEKKLELKGVGYRAQKQGK
                     KLVMNLGFSHPVEMEDPEGITVEAPNQTELIVKGIDKQLVGNYAAKIRAWRKPEPYKG
                     KGIKYVDEVIRRKEGKTGKK"
     gene            8855..9223
                     /gene="rplR"
                     /locus_tag="PC465_002882"
     CDS             8855..9223
                     /gene="rplR"
                     /locus_tag="PC465_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HDF2650167.1"
                     /translation="MLKKADKNANRLQRHKRVRRKISGTSQRPRLCVFRSANNIYAQI
                     IDDTKRVTLVAASSLEAEVKSAVNHTGNKEAAKKVGELVAKKAVEKGITEVVFDRGGY
                     LYHGRIQELAEGAREAGLKF"
     gene            9244..9753
                     /gene="rpsE"
                     /locus_tag="PC465_002883"
     CDS             9244..9753
                     /gene="rpsE"
                     /locus_tag="PC465_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011109776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HDF2650168.1"
                     /translation="MLRRKPIDAGQLDLQEKVVEVRRVTKVVKGGRNFRFAALVVVGD
                     ENGHVGIGAGKAMEVPDAIKKAVEDAKKNLIVVPIVGTTIPHEVRGHFGAGNILIMPA
                     VEGTGVIAGGPARAVLELAGLKDVRAKSLGSNNPRNMVNATIEGLNSLKTVEDIAKLR
                     GKKVEELLG"
     gene            9768..9953
                     /gene="rpmD"
                     /locus_tag="PC465_002884"
     CDS             9768..9953
                     /gene="rpmD"
                     /locus_tag="PC465_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HDF2650169.1"
                     /translation="MAKLQIKLVRSVIGTTPNQKKNVEALGLRKREQVVVKEDNAQTR
                     GMINKVSHLLEVTEIAE"
     gene            9986..10429
                     /gene="rplO"
                     /locus_tag="PC465_002885"
     CDS             9986..10429
                     /gene="rplO"
                     /locus_tag="PC465_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HDF2650170.1"
                     /translation="MKLHELKPAEGAVRAKRRLGRGTATGQGKTAGRGQKGQWSRSGG
                     GVRVGFEGGQMPLARRLPKRGFNNIFKKVYTEVNVEVLNRFENGTEITAELLKSTKTI
                     SKIGKDGIKILGEGNLEKALTVKAAKFTASAQEKIEKAGGKAELV"
     gene            10473..11741
                     /gene="secY"
                     /locus_tag="PC465_002886"
     CDS             10473..11741
                     /gene="secY"
                     /locus_tag="PC465_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HDF2650171.1"
                     /translation="MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSII
                     QKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSG
                     EEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
                     WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLT
                     VTGVTFIQEATRKIPVQYAKRVVGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQ
                     TIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNM
                     KNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGT
                     SLLIVVGVALELKRQLESNLVMRSYQGFLK"
     gene            11758..12408
                     /locus_tag="PC465_002887"
     CDS             11758..12408
                     /locus_tag="PC465_002887"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HDF2650172.1"
                     /translation="MRIILLGPPGAGKGTQAAGIVEKYNIPHISTGDIFRKNIKEGTE
                     LGKKAKEYMDQGLLVPDELTVGLVTDRISQEDCKNGFMLDGFPRNVAQGEHLDIFLKN
                     AGISLDKVVNIEVDKSILVSRAVGRRICKSCGATYHVEFNPPKVEGVCDVCQGELYQR
                     ADDNEETVSKRIQVYLDETKPLVDYYSKQGIIADIKGDQAIDKVFEDIVAALGSGK"
     gene            12409..13155
                     /gene="map"
                     /locus_tag="PC465_002888"
     CDS             12409..13155
                     /gene="map"
                     /locus_tag="PC465_002888"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HDF2650173.1"
                     /translation="MIILKSKKEIELLREAGKIVADTHEVLRKAISPGISTLELDKIA
                     EENIRKYNAEPSFKGYGGFPGSICASINREVVHGIPGETILQEGDIVSLDIGAYYKGY
                     HGDSAKTHGVGMISEEDRKLIEVTRESFYEGIKFAKLGYRLSDISHAVQTHVEKHGFS
                     VVRDLVGHGVGANLHEDPQVPNYGLPGKGPRLREGMVIAIEPMVNAGRYHVKTLSDGW
                     TTVTIDGKKSAHYEHTIAITEHEPLILTKL"
     gene            13177..13446
                     /locus_tag="PC465_002889"
     CDS             13177..13446
                     /locus_tag="PC465_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KOW domain-containing protein"
                     /protein_id="HDF2650174.1"
                     /translation="MLSDNLSIGQVVKVSLGRDKGNLFFVVKIINNEYVLIADGKKRK
                     LDKPKLKKVKHLKKYNFINDEVRKRVVSGQEITDSFLRAELTKLN"
     gene            13484..13702
                     /gene="infA"
                     /locus_tag="PC465_002890"
     CDS             13484..13702
                     /gene="infA"
                     /locus_tag="PC465_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HDF2650175.1"
                     /translation="MAKKDVIELEGTVSEALPNAMFKVKLENGHEILCHISGKLRMNF
                     IRILEGDKVNVELSPYDLTRGRITWRKK"
     gene            13738..13851
                     /gene="rpmJ"
                     /locus_tag="PC465_002891"
     CDS             13738..13851
                     /gene="rpmJ"
                     /locus_tag="PC465_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HDF2650176.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQKQG"
     gene            14004..14375
                     /gene="rpsM"
                     /locus_tag="PC465_002892"
     CDS             14004..14375
                     /gene="rpsM"
                     /locus_tag="PC465_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HDF2650177.1"
                     /translation="MARIAGVDLPREKRAEIGLTYIYGIGKATANEILAKAEINPDTR
                     IKDLSEDQVNELRKVIDDDFLVEGDLRREIALNIKRLRDIKCYRGIRHAKGLPLRGQR
                     TKTNARTRKGPRKTVSRKKKK"
     gene            14411..14809
                     /gene="rpsK"
                     /locus_tag="PC465_002893"
     CDS             14411..14809
                     /gene="rpsK"
                     /locus_tag="PC465_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HDF2650178.1"
                     /translation="MAKPKKKVTRIRRRERKNIERGHAHIQSTFNNTIITLTDVHGNA
                     ISWASSGQLGFKGSRKSTPFASQMAAETAAKAAMEHGLKSVEVFVKGPGSGREAAIRA
                     LQATGLEVTMIKDVTPIPHNGCRPPKRRRV"
     gene            14841..15464
                     /gene="rpsD"
                     /locus_tag="PC465_002894"
     CDS             14841..15464
                     /gene="rpsD"
                     /locus_tag="PC465_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HDF2650179.1"
                     /translation="MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHG
                     QGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDN
                     VVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNL
                     VEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK"
     gene            15542..16489
                     /locus_tag="PC465_002895"
     CDS             15542..16489
                     /locus_tag="PC465_002895"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HDF2650180.1"
                     /translation="MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRIL
                     LSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQ
                     GPCSITGADIICPPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVP
                     IGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLV
                     EHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEE
                     LANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE"
     gene            16510..16851
                     /gene="rplQ"
                     /locus_tag="PC465_002896"
     CDS             16510..16851
                     /gene="rplQ"
                     /locus_tag="PC465_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003357477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HDF2650181.1"
                     /translation="MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRM
                     AEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKG
                     DAAEMAFIELV"
     gene            16971..17804
                     /locus_tag="PC465_002897"
     CDS             16971..17804
                     /locus_tag="PC465_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HDF2650182.1"
                     /translation="MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNG
                     SGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVE
                     EDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMR
                     PKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKG
                     KKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQ
                     L"
     gene            17792..18658
                     /locus_tag="PC465_002898"
     CDS             17792..18658
                     /locus_tag="PC465_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HDF2650183.1"
                     /translation="MSIIVKNLTHIYNEGMPFASKALDDVSFEIKDRDFVGLIGHTGS
                     GKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETID
                     KDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIA
                     MNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVM
                     NHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQ
                     EILKVVRGRGLC"
     gene            18652..19455
                     /locus_tag="PC465_002899"
     CDS             18652..19455
                     /locus_tag="PC465_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDF2650184.1"
                     /translation="MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWP
                     YIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAIT
                     KQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMM
                     TIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADEL
                     AMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI"
     gene            19487..20218
                     /gene="truA"
                     /locus_tag="PC465_002900"
     CDS             19487..20218
                     /gene="truA"
                     /locus_tag="PC465_002900"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDF2650185.1"
                     /translation="MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETS
                     LIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSR
                     YSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSG
                     SSVKDTVRTIYDIDISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDI
                     IQSKTRSRCGHTAPAQGLFLKKVHY"
     gene            20338..20769
                     /gene="rplM"
                     /locus_tag="PC465_002901"
     CDS             20338..20769
                     /gene="rplM"
                     /locus_tag="PC465_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HDF2650186.1"
                     /translation="MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTF
                     TPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVIS
                     HAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK"
     gene            20798..21190
                     /gene="rpsI"
                     /locus_tag="PC465_002902"
     CDS             20798..21190
                     /gene="rpsI"
                     /locus_tag="PC465_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003515879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HDF2650187.1"
                     /translation="MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETL
                     IRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEG
                     FLTRDARMKERKKYGLKAARRAPQFSKR"
BASE COUNT         8600 a         2534 c         4488 g         5869 t
ORIGIN      
        1 gagtggggag ataagatagt agaattattc gagcaaatag atgagtatat accagctcca
       61 gagagagata cagataaacc attcttaatg ccagtagagg acgtattctc aatcacagga
      121 agaggaacag ttgcaacagg aagagtggaa agaggagtac taaaagtaca agacgaagta
      181 gaattagtag gattaacaga agcaccaaga aaagtagtag taacaggagt agagatgttc
      241 agaaaattat tagaccaagc acaagcaggg gataatatag gagcattatt aagaggagta
      301 caaagaaacg agatagaaag aggacaagta ctagcaaaga ctggatcagt aaaggcacac
      361 acaaagttta cagcagaagt atatgtactt aaaaaagaag aaggtggaag acatacacca
      421 ttctttgatg gatatagacc acaattctat ttcagaacaa cagacgtaac aggagcttgt
      481 aagttaccag aaggaataga gatggtaatg cctggagata acgtaacaat ggaagtagac
      541 ttaataaact caatagttgt agaagaggga ttaagattct caataagaga aggtggaaga
      601 acagtagctt caggagttgt tgctacaata atagagtaat cctttactaa actaatggat
      661 ttaatataaa aaaaagaggg ggtaactcct ctcttttttg ttttttgttg acaagtagcg
      721 ctaaagcata tatactaaac tagtgccttg agacagatta acaatcaagt ttaaggttat
      781 gatgttgtaa tagaaaataa aattgaaaaa aacagaaaaa aaacttgaaa aaatgtaaca
      841 gatgatatag aatataatag tgtgcttgag agattaagaa aataataatt aaatcctagt
      901 gaaatacgaa ctgatatcga tttaaaagtt acaacacacc cggagcagtg tatcggtatt
      961 ggttgtacgc aacttgaaaa ttaaacacgt gataaaggag ggaaaacaaa atggctaaga
     1021 atgaaaaaat aagaataaga ttaaaatcat atgatcacaa attattagat ttttcagcag
     1081 gtaaaatagt tgaaactgct aaaaaggctg gatcacaagt ttcaggacct gtgcctctac
     1141 caacagaaaa acaagttgta actatattaa gagctgtaca taagtacaaa gactctagag
     1201 aacaatttga aataagaact cataaaagac taatcgacat agctaatcca acacctaaga
     1261 cagttgactc attaatgaga ttagacttac cagcaggtgt agatatagaa ataaaattat
     1321 aagaacccct aagatattat cctatagatg attatcttag aatgattact ctaaaagatg
     1381 taatccgctg taagaattat aggaggtgct aatatgaaag gaatattagg caaaaaagtt
     1441 ggtatgactc aaatattcac tgataaaggt gtagttatac ctgtaacagc tgttgaagca
     1501 gggcctatgg tcgttactca aataaaaaca gttgataaag atggatacaa tgctatacaa
     1561 ataggttttg aagatgctaa agaaaaagct ttaaacaaac ctaaaaaagg acatttagct
     1621 gctgctaatg ttttaaagaa acatttaaaa gaatttagag tagattctgt agaaggatac
     1681 acagtaggac aagaaataaa agctgatgta tttgaagcag gtgcaaaaat agatgttact
     1741 ggaataagta aaggtaaggg attccaaggt ccaataaaaa gacatggaca aagtagaggt
     1801 cctgaaactc acggttctag ataccacaga agaccaggtt caatgggagc ttgttcttac
     1861 ccaggtagag tatttaaaaa caaaaaatta gctggacata tgggaagcgt aaaggtaaca
     1921 gttcaaaact tagaggttgt taaagtagat gctgacaaga accttatatt agttaaaggg
     1981 gctataccag gagctaaagg ttcagtagta actataaaag aagctataaa ggtttctaaa
     2041 taatgactaa cctagagaaa ggaggaataa caatgccaaa attaaatgta ctaaatgtta
     2101 gtggacaaaa cgttggagaa atagaattat cagattctat atttggcgta gaagttaatg
     2161 gacatgtttt atacgaagtt gtaaaaaatc aattagcaaa taagagacaa ggaactcaat
     2221 ctgctaaaac tagagcagaa gttagaggtg gcggaagaaa accttggaaa caaaaaggaa
     2281 caagtagagc aagacaaggt tctacaagat ctgtacaatg ggtaggtgga ggagttgctt
     2341 ttgcacctaa accaagaagc tacaaatata cattacctaa gaaggtaaga agattagcta
     2401 tgaagagtgc tttatcttca aaagttcaaa atagtgaagt tatagtatta gatgcattaa
     2461 acatggatgc tcctaagact aaagaatttg ctcaaatatt aaacaatata aatgctgcta
     2521 aaaaagcttt agtagttata gctgacaaaa acgataacgt aataaaatca gctagaaata
     2581 tagaaggtgt tcaaactgca ttagttaata ctatgaatgt atatgatata ttaaaatacg
     2641 attcatttat aataactaca gatgctgtta aaaaagtgga ggaggtgtac gcataatgac
     2701 taatccacat gatgtaataa taagaccagt tgtaactgag cacagtatgg ctgaaatggg
     2761 tgaaaaaaaa tacacttttg ttgtggctaa agatgcgaac aaaactgaaa taaaaaaagc
     2821 agtagaaaaa gtattcggag ttagtgttga taaagtaaat actttaaact acgatggaaa
     2881 agttaaaaga atgggtagaa ctcaaggaag aacatcaagc tttaagaaag cagtagttaa
     2941 attaactgct gatagtaaag aaatagaatt cttccaagga atgtagtatt ataacaaacg
     3001 aaggagggaa aacagatggc tataaaaaag tttagaccaa cttctcctgc cttaagacaa
     3061 atgacagttt tagtttctga tgaaataaca tgtaatcaac cagaaaaatc tcttttagtt
     3121 aacttaaaga aaaatgctgg tagaaacgta catggtagaa taactgttcg tcatagaggt
     3181 ggaggacaaa aaagaaaata tagaataata gattttaaaa gagataaaga tggtatacct
     3241 gctaaggttg ctactataga atatgatcca aacagaactg caaatatcgc attattaaac
     3301 tatgctgatg gagaaaaaag atatatatta gctccagttg gaattaacgt tggagatact
     3361 atattatcag gattaggtgc tgatataaaa ccaggaaact gtttagcatt aaaagatatg
     3421 ccagttggta ctatcattca taatatagaa ttaaagccag gaaaaggagc tcaattagtt
     3481 agatctgctg gagtttctgc acaattaatg gctaaagaag gaaaaaatgc tttattaaga
     3541 ttaccatcag gtgagatgag attagtaagc ataaactgta aagctactat aggtcaagtt
     3601 ggaaatatag agcatggtaa cgtagttatc ggtaaagcag gtagaaaaag acatatggga
     3661 ataagaccta ctgtaagagg ttctgtaatg aaccctaatg accatccaca cggtggaggg
     3721 gaaggtagat ctccaatagg tagaccatct cctgttactc catggggtaa accagctctt
     3781 ggatacaaaa ctagaaagaa aaataaagct tcaaataaac taatagtatc aagaagaact
     3841 aagtagtaaa tttatttttg ctcggaaagg aggaatataa atgtcaagat caactaaaaa
     3901 agggcctttt gtccatgcaa gacttttaaa gaagatagaa gctatgaatg ctagtggaaa
     3961 taaagaagtt ataaaaactt ggtcaagatc ttcaactgta tttccacaaa tggtagaaaa
     4021 cactatagct gttcatgatg gaagaaaaca tgttccagta tatataacag aagatatggt
     4081 tggacataaa ttaggtgagt tcgttcctac tagaactttc aaaggacata aggatgacga
     4141 aaaatctaat aagagaaaat aattaaatta tgactaagaa aggaggaata acaatggaag
     4201 caaaagctac tgctaaatac gtacgtgtat caccaagaaa agcaggccaa atatgtgacc
     4261 ttgttagagg aaagaatgtt gatgaagcat tagcaatatt aaagtttact ccaagaggag
     4321 cagcttcaat aatagctaag gttgtaaaat cagctaaagc taacgcagaa aacaatcacg
     4381 aaatggatac tgaaaaatta tatatagcat caatagttgc taatcaagga ccaacaatga
     4441 agagattcat gcctagagct atgggtcgtg caactacaat aagaaaaaga acttctcata
     4501 tagaggttgt tgttaaagaa aaaaaataat taatagatag gagggaaagt aatgggtcaa
     4561 aaggttaatc cacacggctt aagggtcggt gttataaaag attgggactc aagatggttc
     4621 gctactgata aaaaagagtt cggaaactta ttattagaag accataatat acgtaaattc
     4681 ttaaagaaaa gattatactc agctggagtt gctaagatag aaatagaaag atcagctaac
     4741 aaaataaaaa tggacttaca cgttgctaag cctggtgtag ttataggaag agctggtgca
     4801 ggaatcgaag cattaaaagc tgaattagaa aaaatgacaa agaaaactat aatagttaat
     4861 atagtagaag taagaagtac agataaaaat gctcaattag tagctgagaa tatagcttta
     4921 gctatagaga gaagggttgc tttcagaaga gcaatgaaac aagctataca aagagcaatg
     4981 aaatctggtg ctaaagggat aaaagtttct gcttcaggaa gattaggtgg agctgaaatg
     5041 gctagaactg aaggttatag tgaaggaaat gtgccactac aaactttaag agcagatata
     5101 gattatggtt tcgctgaagc tgatacaact tatggaaaaa tcggtataaa agtttggata
     5161 tgtaatggtg aagttttacc aactagagac ggtgtaaatc caagagaaga aagcagaaag
     5221 agcgatagaa gagacaacaa gagagataat agaagaaacg atagaagagg aaatgacaga
     5281 agaggaaatg ataacagagg aaactacaga ggacaaagac ctcaaggtgg atcaagacct
     5341 caaagaactg aaaacaaagg aaattaataa tagttaggtt caaggaagga ggaaaaatac
     5401 tcatgttaat gccaaaaaga gtaaagcgtc gtagagttca tagaggaagc atggctgggc
     5461 aagctcataa gggtaataaa gttacttatg gtgagtttgg attagtagca ttagaagctt
     5521 cttggataac ttctaatcaa atagaagctg ccagaatcgc gatgactaga tatataaaaa
     5581 gagggggaaa ggtttggata aaaatattcc ctcataaacc agtaacaaga aaaccagcag
     5641 agactcgtat gggtgcaggg aaaggttctc cagaatattg ggtagctgta gttaagccag
     5701 gaagagttat gtttgaatta gcaggtgttt ctgaagataa agcaagagaa gctatgagac
     5761 ttgctgcaca taaattacca atcaaatgta aatttgttaa aaaagaagat ttagaagtaa
     5821 agggtggtga ataggatgaa agctaaagaa ttaagagatt taacaagcga agagctaatg
     5881 aacaaattaa acgacttcaa aagtgaatta tttagcttaa gattccaatt agctactggt
     5941 caattagaaa atacagctag aataaagttt gttaagaagg atatagcaaa agttaaaact
     6001 gttcttgctg aaagaaagtt atacgaaact agagcttaat ttggaaagga ggctttttaa
     6061 acatggaaag aggaagaaga aaagttagaa taggccgtgt tgttagtgat aagatggata
     6121 aaacaatagt agtagctgtt gaagaattcg tacgtcatcc actatataat aaacgtgtta
     6181 agagaactaa gaaattcaag gctcatgatg aaaagaatat atgtaacatc ggagatagag
     6241 ttaaaataat ggaaactaga ccattatcta aagataagag attcagacta gttgaagttg
     6301 ttgagaaagt taagtagttt ttgaagaagg agggattacg atatgataca acaagaatca
     6361 cgtctaagag ttgctgataa ctcaggagct aaagaacttt tatgtatacg tgttctaggc
     6421 ggaagtaaaa gaagatatgg taacataggc gacgttatag ttgctactgt taaaagtgca
     6481 acacctggtg gagttgtaaa aaaaggtaag gttgttaaag ctgttatagt aagaagcaaa
     6541 caaggcgtaa gacgtaatga cggaagctat atatcttttg atgaaaatgc tgctgttata
     6601 ataaaggacg ataaaactcc agtaggaact cgtatattcg ggcctgttgc tagagagtta
     6661 agagacaatg aattcatgaa aatagtttct cttgctccag aagtactata attaaggagg
     6721 tgcaatagga catgatgcgt gttaaaaaag gtgacactgt tgtagttata gcaggtaaag
     6781 ataaaggtaa aaaaggttca gttttaaagg tatatcctaa aactagcaaa gtgttagttg
     6841 aaggtgtaaa tgtaataact aaacatcaaa aaccaagtgc tatgaaccaa caaggtggaa
     6901 taataaataa agaagcccca atacacatat ctaatgtaat gccatttgat cctgaaacag
     6961 gaaaaggcgt tagagtaaga tatgaagtaa aagatgggaa caaagtaaga gtatcagcaa
     7021 agagcggaaa agaattataa taaatattgc ttgaaaggag ggaccttaaa tggcttctag
     7081 attacaagaa aaatacatga aagaagttgc tcctgcttta atggagaaat ttggatacaa
     7141 aaacgtaatg gagataccta agttaaataa aatagttatt aacatgggta taggtgacgc
     7201 tagagaaaat ccaaaaggat tagaaaaagg cgttgaagaa ttagaaatga tatcaggaca
     7261 aaagcctgtt ataactaaag ctagaaaatc tgttgctaac ttcaaattaa gagaaggaat
     7321 gccaatagga acaaaagtta cattaagagc tgacaaaatg ttctacttta tggacaaatt
     7381 agtttcagtt tctttaccaa gagttagaga ctttagagga gttaacccta atgcttttga
     7441 tggtagagga aattatgctt taggagttaa agaacaatta atattccctg aaatagaata
     7501 tgataaaata gataaagtaa gaggaatgga tataatattt gttactacag caaaaactga
     7561 cgaagaagct cgtgaattat taaaattatt aggaatgcca ttttctaagt aagcaaagga
     7621 gggattcccg tggctagaaa agcgatggtt gttaagcaac aaagaaagca aaagtacgct
     7681 actagagaat acactagatg tactatatgc ggaagaccgc attcagtttt gaaaaaattt
     7741 ggtatatgcc gtatatgctt tagagaatta gcttataaag gtcaaatacc tggtgttaga
     7801 aaagcaagct ggtagaagtt tgattagaat ggaaggaggg caacaaaatg acaatgacag
     7861 atccaattgc agatatgctt actcgtataa gaaatgctaa tgttgttaag catgaaactg
     7921 tagatgttcc agcttctaat atgaagaaag aattagctag aatcttatta gaagaaggtt
     7981 tcataagagg ttatgatgtt atagaagatg gaaaacaagg tatcataaga atacaactaa
     8041 agtacggaca agaaggcgaa agagttataa caggtcttaa gaaaatatct aagcctggaa
     8101 tgagagttta cgctgctaac catgagatac caaaagtatt aaacggatta ggaatatcag
     8161 ttatatctac ttcaaaagga atattaactg acaagcaagc tagaaaagaa aatgttggtg
     8221 gagaagtaat ctgctacgtt tggtaattaa tatgaacaat gtaaggaggt gcgaccatgt
     8281 caagaatagg tgttaagcca ataataatac cagcaggtgt tgaagttact atagctgaag
     8341 gaaatttagt tacagtaaaa ggtccaaaag gaactttaac taaacaatta agtgctgagt
     8401 taaacataaa aaaagaagaa aatacaataa tggttgaaag accaactgat aataaaaaac
     8461 atagatcttt acacggacta actagaactt tattagataa tatggttgta ggtgtaaata
     8521 ctggtttcga aaagaaatta gaattaaaag gtgttggata tagagctcaa aaacaaggaa
     8581 agaaattagt tatgaactta ggtttctctc atccagttga aatggaagat ccagaaggaa
     8641 taactgttga agctccaaac caaacagagt taatagtaaa aggtatagac aagcaattag
     8701 tagggaatta tgctgctaag ataagagctt ggagaaagcc agagccatac aaaggtaaag
     8761 gtataaaata cgttgatgaa gtaatcagac gtaaagaagg aaaaactggt aaaaaataat
     8821 accaaaactt aaacgctaga aaggagtgag ctaggtgtta aaaaaggctg ataaaaatgc
     8881 taatagactt caaagacata agagagttcg tagaaaaata agcggtactt ctcaaagacc
     8941 aagattatgt gtatttagaa gtgctaacaa tatatatgct caaataatag atgacacaaa
     9001 aagagtaact ctagttgctg catcttcttt agaagcagaa gttaagagtg ctgtcaatca
     9061 tacaggaaac aaggaagcag ctaagaaagt tggagaatta gttgctaaaa aagctgttga
     9121 aaaaggaatc actgaagttg tatttgacag aggtggatac ttatatcatg gaagaattca
     9181 agaattagct gaaggtgcta gagaagctgg tcttaagttc taatacgaag gagggaaaaa
     9241 tacatgctac gtcgtaagcc gatagatgca ggacaacttg acttacaaga aaaagttgtt
     9301 gaagtaagac gtgttactaa ggttgtaaaa ggtggtagaa atttcagatt tgcagcatta
     9361 gtagttgttg gagatgaaaa cggacacgtt ggtataggtg ctgggaaagc aatggaagta
     9421 ccagacgcta taaaaaaagc agttgaagat gctaagaaaa atctaatagt agtgccaata
     9481 gttgggacta caattcctca cgaagtacgc ggacactttg gtgctggaaa tatattaata
     9541 atgcctgctg tagaaggtac aggagtaata gctgggggac ctgctagagc cgtacttgag
     9601 ctagctggac taaaagacgt tagagctaaa tctttagggt ctaacaatcc aagaaatatg
     9661 gtaaatgcta caatagaagg acttaattct ctaaaaacag ttgaagatat agctaaactt
     9721 agaggtaaaa aagttgaaga acttctaggg taaggaggta gtgtaaaatg gctaaattac
     9781 aaataaagtt agttagaagt gttataggaa ctactcctaa ccaaaaaaag aatgttgaag
     9841 cgttaggatt aagaaaaaga gaacaagttg ttgtaaaaga agacaatgct caaacaagag
     9901 gtatgataaa taaagtaagt cacttattag aagtaactga aatagctgaa taatttttat
     9961 aaagtagtgc aaggaggtgc aatccatgaa gttacatgag ttaaaacctg ctgaaggtgc
    10021 agtaagagct aagagaagat taggtagagg tactgcaact ggacaaggta aaactgcagg
    10081 acgtggacaa aaaggtcaat ggtctcgttc tggtggtgga gtaagagtag gatttgaagg
    10141 tggacaaatg ccactagcta gaagacttcc taagagaggt ttcaataaca tatttaagaa
    10201 agtttacaca gaagttaatg ttgaagtttt aaacagattt gaaaatggaa cagaaataac
    10261 tgcagaatta ttaaaatcta ctaaaactat aagcaaaata ggtaaagacg gaattaaaat
    10321 cttaggtgaa ggtaatttag agaaagcttt aactgttaaa gctgctaaat ttacagcttc
    10381 agctcaagaa aaaatagaaa aagctggtgg aaaagcagag ttagtataat aacctgctaa
    10441 tctcctagcc agtacaggcg gggtgaatta gcgtgctgtc aaaattaaaa caagcttgga
    10501 agattaaagc agtaagaaaa aaagtaatgt atacacttat gatgatcgtg atattcagaa
    10561 taggtactac tataccagtt ccaggcatag acactagtat tatacaaaag atggtaggcg
    10621 gcaatagtct actttctctg tataatatgt ttactggtgg agcatttagt aacttttcac
    10681 tatttgcttt aggtataagt ccatatatca ctgcatcaat cataatacaa cttctaacag
    10741 taggttttga aagtttagca gaacttcaaa aatctggtga agaaggaaag aaaaaaatca
    10801 ataagtacac taaatataca gcactagctc tagcagttgt acaagctttg ggaattacat
    10861 taggaattgt aagaagtgct ttaatatcaa atagtgtgtt ttttatcaca actgttgtaa
    10921 taacattagt ttcagcaagt atgttagtaa tgtggattgg ggacaaaatt actgaaaaag
    10981 gaatcggtaa tggtagttca gtaataatat ttgcaggtat aatatcaaga atacctacag
    11041 atgttattaa aatatcgcaa caagttaaat ctggcgaagt tgcaccttgg gttatagtga
    11101 ttctagctgt agttatatta cttacagtaa caggagttac atttatacaa gaagcaacta
    11161 gaaagatacc tgtacaatat gctaaaagag ttgttggaag aaaaatgtat ggaggacaaa
    11221 gttctcatat accaatgaaa gttaaccagt caggagttat gcctataatt tttgctagtt
    11281 cacttttagc tttccctcaa acaatagcta tgtttatggg tccaaatgct caggcttttg
    11341 ttcaaaaata cttaagtatg gcaacagaac aaggattttg gacatataga tcaattgaga
    11401 ttctacttat aattttcttc tcatattttt atacaactgt atcatttaat acagaagaca
    11461 tatctaaaaa tatgaaaaat aatggtggat ttataccagg tataagacca ggtgagccta
    11521 ctatggatta tttaaataga attttaacta gattaacttt agctggagct actttcttag
    11581 caataattgc tatggtgcca gctcttacaa cacattatat gaaagtaaat atgagtctag
    11641 ctgggacttc attgctaatc gttgttggag ttgctttgga gcttaagaga cagttagagt
    11701 caaacttagt tatgagaagc tatcaaggtt tcttaaaata aaatggagat ggataatatg
    11761 agaataatat tacttggacc tccaggtgct ggtaaaggta ctcaggcggc aggaatagta
    11821 gaaaaataca atatacctca tatatcaaca ggagatatat tcagaaagaa tataaaagag
    11881 ggaacagaac ttggaaaaaa agctaaagaa tacatggacc aaggtttatt agtaccagat
    11941 gagttaactg taggtttagt tactgataga atatctcaag aagattgtaa aaatggattt
    12001 atgttagatg gatttccaag aaatgtagca caaggagaac atttagatat cttcttaaaa
    12061 aatgctggta tatcactaga taaagttgtc aatattgaag ttgataagag tatattagtg
    12121 tctagagcag ttggtagaag aatatgtaag tcttgtggag ctacttacca tgttgagttt
    12181 aatcctccta aagtagaagg tgtatgtgat gtatgccaag gagaattata tcaaagagct
    12241 gatgataatg aagaaactgt atctaagaga atacaagttt atctagatga aactaagcct
    12301 ttagtagatt attatagcaa acaaggtata atagcagata taaaaggtga tcaagcaata
    12361 gataaagtat ttgaagatat tgtcgcagcc ttaggaagtg gaaaataaat gattatcttg
    12421 aaatcaaaaa aagaaataga acttttaaga gaagcaggta aaatagttgc tgacactcat
    12481 gaagttttaa gaaaagctat ttctccggga atatctactt tagaattaga taaaatagct
    12541 gaagagaata taagaaaata caatgcagaa ccttctttta aaggatatgg aggttttcca
    12601 ggaagtatat gtgcttctat caatagagag gtagtacatg gtattccagg agaaactata
    12661 ttacaagaag gtgacattgt aagtttggat ataggagcct attataaagg atatcatggt
    12721 gattctgcga aaactcacgg agtaggcatg atatctgaag aagataggaa attgatagaa
    12781 gtaactagag aaagcttcta tgaaggaata aaatttgcta aattaggata tagactttca
    12841 gatatctcac acgcagtaca aacacacgtt gagaaacatg gtttctcggt agttagagat
    12901 ttagtgggtc atggagttgg agcaaatctt catgaagacc cacaagtacc taattatgga
    12961 ctcccaggaa aaggaccaag acttagagaa ggaatggtta ttgctataga gccaatggtt
    13021 aatgcaggtc gttatcatgt aaagactcta tcagatgggt ggacgactgt tacaatagat
    13081 ggaaaaaaat cagctcatta tgagcatacg atagcaatta ctgaacatga acctttgata
    13141 ttgacaaagt tgtaatttaa aaagtaggtg aaaaaagtgc tatcagataa tttaagtata
    13201 ggtcaagttg ttaaagtttc attaggacga gataaaggaa atttattctt tgtagtcaaa
    13261 ataattaata atgaatatgt attaatagct gatggaaaaa agagaaaact tgacaaacct
    13321 aagttaaaga aagtgaagca cttaaaaaaa tataatttta ttaatgatga agttagaaaa
    13381 agagtagtat ctggacaaga gattacagat tcttttttaa gagctgaact tactaagtta
    13441 aattagataa tttaacttat tgaaatggag ggctggttag ttaatggcca aaaaagatgt
    13501 tatagaatta gaaggtacag tttcagaagc tttacctaat gctatgttca aagttaaact
    13561 agaaaatgga catgagatat tatgccacat ttctggaaag ctaagaatga acttcataag
    13621 aattcttgaa ggtgacaagg tgaatgttga actttctcca tatgacctta caagaggaag
    13681 aattacttgg cgtaagaagt agactatatt aatatttagt ctaaggaggg attaataatg
    13741 aaggttagac catcagtaaa accaatatgt gaaaaatgta aagtaataaa aagaaaagga
    13801 aaagtaatgg ttatctgtga aaatccaaag cataagcaaa agcaaggata agaaattatt
    13861 actagcattt tgttaaattt tatagtataa tactatattg tgatgttaac aaaagaacgt
    13921 taaaatcgtt gaacaatctg gcgtaggatt ggcatatgat gtgaagtttt aaacactaaa
    13981 aactatgtgt aggaggtgcg atcatggcaa gaatagctgg ggtagattta cctagagaaa
    14041 aaagagcgga gataggctta acttatatat atggtatagg taaagcaact gctaacgaaa
    14101 tattagctaa ggctgagata aatccagata ctagaataaa agatttatca gaagatcaag
    14161 ttaatgagtt aagaaaagtt atagatgacg atttcttagt tgaaggtgac ttaagaagag
    14221 aaattgcttt aaacataaag agattaagag atataaaatg ttatagagga ataagacacg
    14281 ctaaaggtct tccattaaga ggacaaagaa ctaagactaa tgctagaact agaaaaggtc
    14341 ctagaaaaac agtatctcgt aaaaagaaaa aataaataaa taataactag atgaaggagg
    14401 gaaaaggaaa atggctaaac caaaaaagaa agttacacgt attagaagaa gagaacgtaa
    14461 aaatatagaa cgtggtcatg ctcatataca atcaactttc aataatacaa taataacttt
    14521 aactgacgtt cacggaaatg ctatatcttg ggcaagttct ggacaattag gattcaaagg
    14581 atcaagaaaa tcaactccat ttgcatctca aatggctgct gaaacagctg caaaagctgc
    14641 gatggaacac ggactaaaaa gtgttgaggt attcgtaaag gggccaggtt caggaagaga
    14701 agctgcaata agagctttac aagcaactgg actagaagta actatgataa aagacgttac
    14761 tccaatccca cataacggat gcagaccacc aaagagaaga agagtgtaat taataagagt
    14821 acaataggag gtgtagataa atggcaagat atacaggtgc atcatgtaga caatgccgta
    14881 gagagggaat gaaattattc cttaaaggtg atagatgtta tacagacaaa tgtgctatag
    14941 taaaaagaaa ctatgctcca ggtcaacatg gccaaggaag aaagaaagtt tctaactatg
    15001 gattacaatt aagagaaaaa caaaaagtta aaagaatata tggagtttta gagactcaat
    15061 ttagaaattt atatgaacgt gctgaaaata tgcctggtaa agcaggtgag aacttattaa
    15121 gtttattaga gagaagatta gataatgtag tttacagaat gggactagca tcttctagaa
    15181 aagaagctag acaattagtg actcatggtc atttcacttt aaatggaaat aaagtagaca
    15241 taccttcatt aatagttaag gttggagatg ttatagaagt taaagagaaa tcaagatctt
    15301 ctgcaaaatt caaaaattta gtagaagtta actcaagaat agctcctaag tggttagaag
    15361 ctaatgtaga aggaatgaca gcaaaagtag ttggtgttcc aacaagagaa gatatagatc
    15421 ttgagatagc agagcactta atcatagaac tttactctaa ataataagca cacttttaaa
    15481 aattatttta aaattttgtt taccctcagt ggattactga attttaagga gggttttgtc
    15541 catgatagaa atagaaaagc caaaagtaga tatagttgag cttagcgaag actatagata
    15601 tggtaagttt gttatagagc ctctagaaag aggatatgga ataactatag gtaacgcatt
    15661 aagaagaata ttattatcat cattaccagg tgtagcagtg aatgctataa aaatagatgg
    15721 agttcttcat gaattttcaa caatacctgg tgttaaagaa gatgttactg agataatatt
    15781 aactttaaaa gagctttcag caactataga tggtgaagga agtagaacac ttaaaataga
    15841 agctcaagga ccatgctcta tcacaggtgc agatataatc tgtcctccag atgttgaaat
    15901 attaagtaaa gatttagcaa tagctacatt agatgataat gctaaactta atatggagat
    15961 atttgtagat aaaggtagag gttatgtttc tgctgaagaa aataaaacag agaatgttcc
    16021 aataggtgtt ttacctgtag attcaatata tactcctgtt gagaaggtta gttatcatgt
    16081 ggaaaacaca agagttggtc aaaaaacaga ttatgataaa ttagtactag aagtttggac
    16141 taatggtagt ataaatcctc aagagggaat atcattagct gcaaaggtat tagttgagca
    16201 tttaaactta tttatagact taactgaaca tgtaagtagt gttgaaatca tggtagaaaa
    16261 agaagaagat caaaaagaaa aagttcttga aatgactata gaagaattag atttatcagt
    16321 tagatcatat aactgtttaa agagagcggg aattaataca gttgaagaat tagctaataa
    16381 atctgaggat gatatgatga aggttagaaa cctaggtaag aagtcattag aagaggtaat
    16441 acaaaaacta gaagaacttg gattgggatt aaaaccaagt gaagaatagc gagcaaagga
    16501 gggataagaa tggctaagta ccgtaaatta ggacgtgaaa cagctcacag aaaccttatg
    16561 ttaagaaact tagtaacttg cttactaaga agtggaagaa tagaaactac agtgactaga
    16621 gcgaaagaaa ctcgtagaat ggctgaaaag atgataactc ttgctaagag aggagatctt
    16681 catgctagaa gacaagtttt agcttatgtt atggatgaaa cagtagttaa taacttattc
    16741 acagatttag ctccaaaata tgctgagaga aatggtggat acactagaat aataaaaata
    16801 gggccaagaa aaggcgatgc tgctgaaatg gcttttatag aattagtata gtaaggaaag
    16861 gattaggctt gatggcttaa tctttttttt atttttttga ctaaggtatg atataataat
    16921 gtgtaaaatg atttttataa gttattgctt actaaaagga gtatgagtta atggataata
    16981 tagtaaaggt aaataatatt tcgtttgagt atattacaga tgaagcaaaa cttaaagcaa
    17041 tagataattt aagcctagat gttaaaaaag gagaatttgt tgcgataata ggacataatg
    17101 gttctggtaa gtctacttta tctaaaaact taaatgctat tcttatgcct actgaaggaa
    17161 atattcttat tgatgatatg gatactaaag aagaagaaag attatgggat ataagacaaa
    17221 ctgcaggcat ggtatttcaa aatccagata atcaaatagt tgctactata gtagaagaag
    17281 acgttgcatt tggacctgag aacttaggta tagaaccaaa agaaataaga cgaattgtag
    17341 aggagtcttt aaaaagtgta ggtatgtatg atttaagaga tagacagcct catttgttat
    17401 caggaggtca aaagcaaaga gttgcaatag caggaattat tgctatgagg cctaaatgta
    17461 taatatttga tgaagcaaca gcaatgttag atccatctgg aagaaaagaa gttatgaaaa
    17521 caataaaaag acttaataag gaagaaaata taactgttat acatataacg cactttatgg
    17581 aagaagcagt agaagctgat agagttgtag ttatggaaaa aggaaagaaa atcttagagg
    17641 gaactcctag agaagtattc agtaaaataa agatgttaaa ggaaatcggt ttagatgtac
    17701 cttgtatgac agagttatct agtttattaa tagaagaagg tataaatatt agtagtgata
    17761 tattaactgt ggatgagatg gtgatggaat tatgtcaatt atagtaaaga atttaacaca
    17821 tatatataat gaagggatgc cttttgcaag taaggcactt gatgatgttt cttttgagat
    17881 taaagataga gattttgttg gtcttatagg tcatacaggc tcaggaaaat ctacattaat
    17941 acaacattta aatggattac taaagccttc ctcaggagaa atatttataa atgattttaa
    18001 tataacagat aaaaacttga atttaactga gattagaaaa agagtagggg ttgtatttca
    18061 atatccagaa taccaattgt ttgaagaaac gattgataaa gatatagctt ttggaccctc
    18121 taatttaggc ttagaggagt ctgagataca taacagggta aaagcatcaa tggaagctgt
    18181 aggacttgat tatgagggat ttaaagacaa atctcctttt gaattatctg ggggacaaaa
    18241 gcgtagagta gcaattgctg gagttatagc catgaaccca gaagttctca tattggatga
    18301 accaactgct ggtcttgacc ctggtggaag agatgaaatt tttaacttaa taaaagactt
    18361 acatgaaaaa aagaatatga ctataatact atcatcacat agtatggatg atatggcaaa
    18421 gttagcaaaa actttaattg ttatgaatca tggtagcgta gaatttatgg gaactcctag
    18481 agaagtattt aaatcaaatg ctagtaaatt aaaagatata ggattagata ttccacaagt
    18541 tttagagctt gcattgaaat tgagagaaaa aggctttgac atcagtgagg atatattgac
    18601 tttagaagaa gcaaaacagg aaatattaaa agttgtgaga ggacgaggat tatgttaaaa
    18661 gatataacta tagggcaata ctacccaaca agttctgcta ttcataaatt agatccaagg
    18721 ataaagcttg tagcgacaat tgtatttatg gtatctatat ttgtagtaaa taaattttgg
    18781 ccttatatag tagttttatt atgtttatta gctatgataa aattggctaa tataccagtc
    18841 aaatatattg ttaagggtgt taaacctctt aaatggatta ttttgtttac atttcttata
    18901 aatatttttt tcttaccagg tgatgaaata tggtcatttg gatttttagc tattacaaaa
    18961 cagggtctaa gacaagcaat ttttatggca ataagattaa tatttttagt agttggtaca
    19021 tcattgctta ctttaacaac ttcaccaata gaattaactg atggaataga gagattgttg
    19081 aatccattta agaaaattgg tttgccagtt catgaacttg caatgatgat gacaattgct
    19141 ttacgtttta ttcctacatt gttagatgag acagacaaaa taatgaaggc tcagatgtct
    19201 agaggtgcag attttgaaag taagaatctt ataaatagag caaagaattt agtaccactt
    19261 ttggtacctt tatttgtaag tgcatttaga agagctgatg aattggctat ggccatggag
    19321 gccagatgtt acagaggtgg acataatagg actaagatga gagagtctgt tatatcaaga
    19381 agggattata tggcatgtgt atttcaggtt gtttatctgg gagcaattat agctactaga
    19441 tttatagcaa tttaattaat aagttataga tataatgagg taaagtatga gaaatataaa
    19501 aattaaaatc caatacaatg gtaagaatta ttgtggatgg caaaagcaac ctgattcttt
    19561 agggatacaa ggtacaattg aaagggctat atatgatata acaaaagaag aaaccagtct
    19621 tatagggtct ggtagaactg attcaggagt tcatgctatt ggtcagattg caaattttaa
    19681 aattaattca ggtataagta tagaaagtat accaatggca ctaaatgcca agttgccaaa
    19741 agacatatca gttatagaag catgtgaagt aaatgatgat tttcactcca gatacagtgc
    19801 aaaaggtaaa acatataaat atttagtata taatagcaag tttagaaatc caatacttag
    19861 tgagatatca tatcaagtaa aatatgaact tgattttgat aaaatgtgtt cagaagcaaa
    19921 aagtttatta ggaacacatg attttaaagg ttttatgagt tctggttcat ctgtaaaaga
    19981 tacagttaga acgatatatg atattgatat aagtaaaaaa gatgacttga ttacttttga
    20041 gattagtggt aatggttttt tatataacat ggtgaggatt attgttggaa cacttgttga
    20101 tatgggtcgt ggcagaatta acgaaccatt tttagatata atacaatcaa aaactaggtc
    20161 aagatgtgga catacagctc cagcacaagg attatttctc aaaaaagttc attattaact
    20221 tgacacacca ggctacatgt attaaaatat atgagaatgt gttaataagt ccacttgccc
    20281 cggacttgac ataaacggta aaaaaatttt atgaaaagta gttaaggagg gacagttatg
    20341 aaaagttata tagctaagcc agctgatgta caaagaaaat ggtacttagt tgatgctgaa
    20401 ggaaaaacat taggtcgttt agcaacagaa attgcgacag tattgagagg taaacataaa
    20461 ccaacattta ctcctcacgt tgatggtgga gattttgttg ttgtagtaaa tgcagaaaaa
    20521 atagttttaa gtggtaagaa attagatcaa aaatattaca gataccatac tggttatgta
    20581 ggtggattaa aagaaatatc ttatagagat atgatggata agaaaccaga agaagttata
    20641 tcacatgctg taagcggtat gttacctaaa aataaattaa gaagcagaat gatgactaga
    20701 ttaagagtat ttgcaggtgc tgagcacact catgcagctc aaaatccaga agttttaaac
    20761 tttaaataag attaataggt gaaaggagga gtttataatg gctaacgttc aatattatgg
    20821 aactggaaga agaaaaagtt ctgttgctag agtaagacta gttgcaggtg aaggaaatat
    20881 attagtaaat ggaagagcat tagaaaatta ttttaattat gagacattaa taagagatgt
    20941 taaacaacca ttagttttaa ctggtaatga aaataaatat gatgttatag taaaagttga
    21001 aggtggagga ttcactggac aagctggagc tataagacat ggaatatcta gagctttatt
    21061 aaaagctgat ttagatttaa gacctgcttt aaagaaagaa ggtttcttaa ctagagatgc
    21121 aagaatgaag gaaagaaaga aatacggatt aaaagcagca agaagagctc cacaattctc
    21181 aaaaagataa ttacttattt ttttggaaaa gcaaaatctt ttatttactg ttattcagaa
    21241 agtattggta ttttaaaaat gttgggttaa gttaattatt gatatataat aaaataataa
    21301 gatatcttat taggatgttt ttcattaaga agaacatcct ttttattttg actatttaat
    21361 aaaaaacata tgctaataac atttaaattt tatttttata atattgtaat ttaaaagttt
    21421 atataaggtt atatatttta agatattatt taacaatata aattctgaat atacgttatc
    21481 aaagtttata a
//
LOCUS       DAMJXI010000062        21264 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.064, whole genome shotgun sequence.
ACCESSION   DAMJXI010000062 DAMJXI010000000
VERSION     DAMJXI010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21264
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.064"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            464..1525
                     /locus_tag="PC465_002903"
     CDS             464..1525
                     /locus_tag="PC465_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HDF2650188.1"
                     /translation="MRDFLKNYKSSIILLACTIVGAIVGLVLGPKASILKPFGDLFIN
                     ALLMIVVPLVFLSVSSGVASIKNMERFGKIMKGTAIVFMGTTLVIAFLGITSALLFNP
                     SKGLDVSSVKNLMVAQDAETLESKGTLLDQVVSSITVKNFGDLFSSSNLLQSVIFAIL
                     IGTAIAMMGDRGNTIRKLLSEGTEAILKVVSIFMLYAPIGLGCYTATIIGELGSKIIQ
                     GYVRVFVIYSLTAAMYFLLFYSLYAFLSAGKQGFRQFWRNAIKPIATALATSSSSACI
                     PSNLEASKNIGVPDDISETVIPLGINIHKDGSVLAVIIKVAFLSGILGSGMANPATIG
                     QLFITVFVVGVFMAPVAGG"
     gene            1538..1735
                     /locus_tag="PC465_002904"
     CDS             1538..1735
                     /locus_tag="PC465_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HDF2650189.1"
                     /translation="MLVVSIFGFPVEAIPLLTVITTITDIPNTILNTTGNTVSSMLVS
                     RLVEGKDWLIDKTAITTKKIS"
     gene            complement(1899..2603)
                     /locus_tag="PC465_002905"
     CDS             complement(1899..2603)
                     /locus_tag="PC465_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF2650190.1"
                     /translation="MQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEMLECLGVVD
                     KTYPKDSIIFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLFGEVFACTR
                     LHKSNVTVTTTSSCEVLFIKFKSVTGICSSACVFHNRLVENMLQLIAEKNILLHNKIE
                     LLSRKTTREKLLMYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRELGKMRDEG
                     LLSFNKNKFEIFYFKK"
     gene            2768..3493
                     /locus_tag="PC465_002906"
     CDS             2768..3493
                     /locus_tag="PC465_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2650191.1"
                     /translation="MMRKIIKIDEEKCNGCGLCVEACHEEAIGMVNGKAKLLRDDYCD
                     GLGDCLPTCPTNAISFEYREAAEYDEAAVKANMEAKKAQKKTLACGCPGSQSKSINRE
                     VSNSTSISNDIVEIKGSQLNQWPVQIKLVPTNASYLKNASLLIAADCTAYAYGNFHNK
                     FMKNKVTLIGCPKLDEVDYAEKLTEILKENDIKNIVVTRMEVPCCGGIVNAVKTALQN
                     SGKMIPWQIVTISVDGKIVDGEI"
     gene            3553..5145
                     /gene="hcp"
                     /locus_tag="PC465_002907"
                     /gene_synonym="priS"
     CDS             3553..5145
                     /gene="hcp"
                     /locus_tag="PC465_002907"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HDF2650192.1"
                     /translation="MEKMFCFQCEQTAGGKGCTINGVCGKKGGTANLQDELTGVLIGL
                     SRATIGNKNRPTSETDKIMIEGLFTTITNVSFDDEAIKRQIEKTEVEKSKLVPRCSDC
                     STTCNRNDNYDMKDLWNDNEDIRSLKSLILFGLRGMAAYAYHAMVLGYTDKDVNEFFY
                     EGLIAVGGDLSIDELLGLVMKTGEINLKCMELLDRANTETYGTPEPTQVSMKIEKGPF
                     IVVTGHDLYDLHKLLEQTKDKGINIYTHGELLPAHAYPKLKEYKHLKGNFGTAWQNQQ
                     KEFDNIPAPILFTTNCLMPVKDSYRDRVFTTEVVAYPGMVHIDEDKDFSSVIEKALEL
                     GGYREDVHMTGINGGDTLTTGFARGTVSSVQDKVVDAVKSGAIRHFLLVGGCDGAKPG
                     RNYYTEFVKQAPKDTVILTLACGKYRFNDLDLGDIGGLPRLMDMGQCNDAYSAIKVAV
                     SLANAFECGVNDLPLSMVLSWYEQKAVCILLTLLHLGIKNIYIGPSLPAFLSKNVLDI
                     LVDKFALTPISTPEEDMKKILG"
     gene            5516..6421
                     /locus_tag="PC465_002908"
     CDS             5516..6421
                     /locus_tag="PC465_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF2650193.1"
                     /translation="MKNSNFNILAFDGGGLKGALSISILERIVKEYPNLLNNINMFGG
                     TSTGSLIALGLAYGVSPKEIKELYSIENSKYIFNKSYAEILRPKYENKNLKEVLLSIF
                     PEELELKDLNKLVMIPSFYIGNEENAWKPVFYNNMPNSFTKTSKVVDVAMASSAAPVF
                     FPTYNRHVDGGIIATDPSLACIIHAIDSGFRLKNTRLFSIGTGYVYNSIKADTTEWGA
                     IDWIINKEPDLPIISITLEGNSQMSQLFSQKLLGDNYYRLNPKMEKDVAMDDCDALEY
                     LMSLGENCDIKDAFGWIKKKSFYRN"
     gene            6545..7498
                     /gene="msrA"
                     /locus_tag="PC465_002909"
     CDS             6545..7498
                     /gene="msrA"
                     /locus_tag="PC465_002909"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDF2650194.1"
                     /translation="MIKLATFAGGCFWCMVKPFDKYDGVIKVVSGYTGGHVENPTYQE
                     VCSGTTGHLEAIQITYDDDIISYDELLNIFWKQINPTDDGGQFGDRGTQYKTAIFYHD
                     EEQKNIALESREHLENSKIFDSKIVTDIIPATKFYEAEENHQDYYKKRPLNYNMYYKG
                     SGRYNFVKSHWDGNNINREELKKTLTPIQFEVTQNDMTEVPFENEYYDNNKEGIYVDI
                     VSGEVLFSSKDKFDSGCGWPSFSKPVIDKSIIERSDFSQGMYRVEVRSAKGNSHLGHV
                     FDDGPKELGGLRYCINSASLKFIPRENMEALGYGEYLKLFE"
     gene            7651..8781
                     /locus_tag="PC465_002910"
     CDS             7651..8781
                     /locus_tag="PC465_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2650195.1"
                     /translation="MNLKDFNGKRLKSARIFRAKTIEQLSKETKINKKDLKAFEENKY
                     VPNIENTLKLSNILNFPKEYFYKNENINIVVEDSHFNPQSKLPRVEEISYREKIIIIH
                     KIYSFMENYIKFPKENLPNRKVMSDININDIESLAYKTREFWDLNSTPIVNMVSLLES
                     KGIIISGMNVDRKGATIFTQKQRISKESKYLISLGNDKKSASIRNYTLACELGYIISS
                     ELRIPSKQFSEDEYACAFLLPKESFLKDLTHPEDLDYYVELKKKWIVPISAMIFRAYN
                     LEKINYKKYNYLMNEMDKKGWLIEEPLDKMKGSSPTYLKRAVELLIENKIMSVNSIVS
                     SLEEFGINLYPEDLELLMGLKKGLLSQEVNKKSKVIKFDGKK"
     gene            complement(8898..9866)
                     /locus_tag="PC465_002911"
     CDS             complement(8898..9866)
                     /locus_tag="PC465_002911"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HDF2650196.1"
                     /translation="MAIKPRKISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSK
                     AQALDLADAVSYLPHKVHIEKGTFSDCKDSDIVVISVADSSEGPLRRQNTTRLDLLRP
                     TIGMIKSIVKPIVDSGFDGIFVVISNPVDVVTNYIWEKSGFPKNKVIGTGTALDSTRL
                     RRILSEETGIAQQSIQAYSMGEHGDSQMVPWSHVSIGGKPILDMIKDNPSTYSNLDLP
                     SIVEKNKKTGISIINGKDCTEFGIGTALVEIVKAILHNEKKVLPVSTLLEGQYNERNV
                     FAGVPCVIGKDGIEEIIEINMTEYEQNEFNKSCSVLREYIALSKTL"
     gene            10201..10389
                     /locus_tag="PC465_002912"
     CDS             10201..10389
                     /locus_tag="PC465_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650197.1"
                     /translation="MNYHTKEELVEALRVISSSIINCEKGQKKFSEETSHHTCFKNII
                     EAIYISKSLIMDEISKRD"
     gene            10649..11848
                     /locus_tag="PC465_002913"
     CDS             10649..11848
                     /locus_tag="PC465_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanyl-tRNA editing protein AlaX-L"
                     /protein_id="HDF2650198.1"
                     /translation="MEKLYYTNQYIRDFTAEIIEIKEVENKYHVLLDKTAFFPGGGGQ
                     FGDLGKIENDDVINVYEDGKKIYHVLDKKPIKIHKVKCSIDWDRREDGMHQHFGQHVL
                     SGCFFKTFNANTTGFHLGNEYSTVDIEGNLEEDKIREIELFANEIIRQNIQVETLLPT
                     KKELKKIWLRRDLPNTDEEIRVIKIGDLDTNACCGVHPKSTGELRMIKIKKWEKHKSS
                     TRIEFLAGKRAVDEVLKRDIYLTKICRYLSCSEEDAINGIVNLNSKVEEALIKKRRLE
                     EVVSTYQVKEMIEKANKVGNISVIKKIYDDEDLKYVNKIANKIAEYENSIALLAVKFN
                     DKINLVFACSKNLKDINMGVLLKDAINLIDGKGGGSKVLAQGGGKNNGNLEATLDYAF
                     MKIEKTL"
     gene            11900..12403
                     /locus_tag="PC465_002914"
     CDS             11900..12403
                     /locus_tag="PC465_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2650199.1"
                     /translation="MEQQKDYIELYENEELIEIREARMDDLDTIAKFNYNLAKETEGK
                     ELDMDVLTKGVKALLLDERKGKYHVYTVFDKVVAQIMYTYEWSDWRNGNFLWIQSVYV
                     DKEYRRKGIFNYLFNYIKNICDKDENIVGMRLYVEKENINAKATYESLNMYECDYNMY
                     EYEVIHS"
     gene            12510..12827
                     /locus_tag="PC465_002915"
     CDS             12510..12827
                     /locus_tag="PC465_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650200.1"
                     /translation="MGVLKGMFYVFLFLDLVSIFCFFFNKGKIASNKIVFNAIGVLTF
                     VLCFMLFSYYPNNNLIGKFIASLFFIFGVAGVMLKEKNFLYARLLLTVVIVFSTLRLF
                     VIQ"
     gene            12985..13944
                     /locus_tag="PC465_002916"
     CDS             12985..13944
                     /locus_tag="PC465_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDF2650201.1"
                     /translation="MIESKKSEKLLLSIIYIIFLVYILMIIRIILFRDVPIYAIFKGT
                     FRNVNLIPFYTIYQFIVDSNLDFMKATVNIIENIGIFIPMGIFLPIVCKNLNKKTIII
                     VIILVSLAFELTQYIFALGSSDIDDVILNSLGGIIGINIYINMNKLFPNDINRFKAII
                     GTSLVLGVIGLGVISKNYHNLLTFKFRPDRKISKILIEENREIIKDINKDTVDIVGTF
                     ESFKKGIITIKAGSNNKVKRPENLIDSDGNIRIYLNENTKLVSYIITKESKMDIVKYE
                     EFDVKNLDLLRRYDTINVWIDKENQPKDKHGIMASKLLIGLYE"
     gene            14059..14844
                     /locus_tag="PC465_002917"
     CDS             14059..14844
                     /locus_tag="PC465_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650202.1"
                     /translation="MEIIKYILYFFIYSFLGWTVESIGCSIASKRIINRGFLNGPICP
                     VYGFGAVIVISLLGRFNNVVIVFLLGMILTTILEYFTGFILETLFHAKWWDYSDRKFN
                     IKGRVCLKNAIYFGVMSVLIIRFIHPFIKYFVSIIPYRILISMAIITTLWTILDLIVT
                     IITLKKLDIKLNLLDDIITDLNDINVKLDKFDRGEIQALFKTINNDELEVREKINKIN
                     SKLDRIESNIILQKRVIKAFPHIKHKKQQEQLEHFKKIINEKR"
     gene            15136..16455
                     /locus_tag="PC465_002918"
     CDS             15136..16455
                     /locus_tag="PC465_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2650203.1"
                     /translation="MSEITSQMISTEEKKYVAKTQKIPYYPVAFKSGDGAMLYDYEGN
                     EYVDFLASAGSANVGHGNKEISQAVKEQMDDITQYTLAYFHSDPPVKLAEKLVEIAPG
                     DNDKKVLYSATGSACIDAAIKLARGYTGRTKIISMCESYHGSTYGAISISALSTNMRR
                     KMGPLLPEVYHFHYPDKNRTAKECLDEIEYAFAHYLPAEEVAAIFIEPIAGDAGIIVP
                     PVEWVQGLSKICKENGILLVSDEIQQGMGRTGKWFGIENFGVEADLIVLGKSVGGGLP
                     LGAVVGRTEIMQSLDAPAHLFTLAGNTTVCVAALKSIEIIEKENLLQKSIEMGDYIKA
                     GFEKLKEKYDIIGEIRGIGLSIGVDIVKGKGSNEKHPDATAKICYRCIQTGLIMIFLG
                     QSTLRVQPPLVITKEQVDKAMNIIDSAIDDYLNGRIGDEVYEVTQGW"
     gene            complement(16530..16958)
                     /locus_tag="PC465_002919"
     CDS             complement(16530..16958)
                     /locus_tag="PC465_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650204.1"
                     /translation="MKDNNNTNKTIQFGEKKASLENNIQKNKNIKLDNTHKVIPYPKN
                     RKKDDKKKGNKKKNTSTSKVNKNNYGHSFFNNKYKYKRKPYVIALYTVILILLAILII
                     TKLTDSTNKGNYSRNTVSDTHKNDIRNIVFNESNNFLICG"
     gene            complement(17049..18425)
                     /gene="hydG"
                     /locus_tag="PC465_002920"
     CDS             complement(17049..18425)
                     /gene="hydG"
                     /locus_tag="PC465_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydG"
                     /protein_id="HDF2650205.1"
                     /translation="MFINHELINSLLEDAKNSTSDDIEKVLDKADRREKLSYKDIATL
                     LEVEDKKQLDRLFSIAGQIKNEIYGNRVVLFAPLYVSNYCVNECVYCGFSKCNKFKRK
                     KLTMEEIKEEVKILEKMGHKRLALEAGEDPKNCDINYILDCLDAIYSTYNENGNIRRV
                     NVNIAATSVDEYKLLKEKGIGTYILFQETYHKPTFIKMHGQSIKNDYYYHLTAFDRAM
                     EAGVDDVGAGVLFGLSDPKFEVLGLMMHNEHLEEKFGVGFHTISFPRLKKAEGMSLED
                     FPHLVSDDMFKKIVAITRLAVPFTGIIMSTRETAEMRNELLKYGVSQISAGSLTGVGG
                     YKAYEDGDNTEQFEVGDHRSPVEVLKELITDGYIPSYCTACYRKGRTGDRFMSLAKSR
                     QIHNVCTPNALTTLNEFLIDYGDEELKIMGKKLIAEEIGKIEREDIRNIVSNNMTALE
                     RGERDLYL"
     gene            complement(18426..19511)
                     /gene="hydE"
                     /locus_tag="PC465_002921"
     CDS             complement(18426..19511)
                     /gene="hydE"
                     /locus_tag="PC465_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydE"
                     /protein_id="HDF2650206.1"
                     /translation="MTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRN
                     YLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSLDEILE
                     CCDIGYKIGYRTFVLQGGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKK
                     YFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPF
                     QNNEDLVRDLLYLKELNPHMVGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPK
                     VLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYH
                     QSLEENIKSLGLEVDYSRGDNIEWRRL"
     gene            complement(19547..20755)
                     /gene="hydF"
                     /locus_tag="PC465_002922"
     CDS             complement(19547..20755)
                     /gene="hydF"
                     /locus_tag="PC465_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster maturation GTPase
                     HydF"
                     /protein_id="HDF2650207.1"
                     /translation="MSLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAG
                     TTTDPVFRPMEILPIGPCVLIDTAGLDDVGELGELRIGKSLDVLEKTDIALLVVDCQI
                     GISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIG
                     IENLKNEIIKVLPKDSTEFKLVSDLIEPNDLVVLVVPIDKAAPKGRLILPQQQVIRDI
                     LDNGAISIVTKEDSLKETLSNLGKKPKLVITDSQVFPQVDKDTPKDIPLTSFSILFAR
                     QKGDLKELINGAYALENLKDGDKILMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITF
                     EFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGVLIAYVKGI
                     LERSLELFNY"
     gene            complement(20770..21021)
                     /locus_tag="PC465_002923"
     CDS             complement(20770..21021)
                     /locus_tag="PC465_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-only hydrogenase system regulator"
                     /protein_id="HDF2650208.1"
                     /translation="MKKVAVISAILEEPKECQFKFNEVVSGFKGIIKGRMGIPCEEEG
                     VSIVCIAVVGEMDTINSLTGKLGNIPHVSVKTSISKKEV"
BASE COUNT         8027 a         2490 c         3420 g         7327 t
ORIGIN      
        1 actatttgaa aattcttttt aaaagtatat caaaatatca aatacataaa aaaataatat
       61 ttgacaaagt atcatatgtg tttacaaaat caactttatg gagttatata gtataggaat
      121 tacaatgaat atactaaaat tttatattaa agtacaaagt attaaatttg aaaataatta
      181 agtaatatta tatatatttt tttatattgt ttgttttatt aaaattaatc tagaaaaaaa
      241 gttttaaaag cagaatttta ttaatattta tatatagata tgaactatta ataaaacgtt
      301 aaaaatacaa aaaaactata gaaattgaca tatattccag tatttgctaa agtagctgtt
      361 ggggaaaatt acaaaaatta ttaatgcgca ttagataatt tactttaatt tttttagcat
      421 ttggggtaat ttataatata aagcattaga aaggaaaata taaatgaggg actttttaaa
      481 aaattataag tcatcaatta tacttttagc atgtactata gtaggggcga tagtaggatt
      541 agtacttggt ccaaaagctt caatactaaa accatttgga gatttattca taaatgctct
      601 attaatgata gtagtaccat tagtttttct tagtgtttct tcaggtgttg ctagtataaa
      661 aaatatggaa cgatttggaa aaataatgaa gggtacagct atagtattta tgggaacaac
      721 acttgtaatt gcatttttag gtattacatc tgcattatta tttaatccgt ctaaaggatt
      781 agatgtatca agtgtaaaaa atttaatggt ggctcaagat gcagaaactt tagaatcaaa
      841 aggaacgtta ttagaccaag tagtatcaag tattacagtt aaaaattttg gagatttatt
      901 ttccagtagt aatttactac aatcagttat atttgcaatt ttaattggaa cagcaatagc
      961 tatgatggga gataggggaa atacaataag aaagctttta tcagaaggaa cggaagcaat
     1021 attaaaagta gtaagtatat tcatgcttta tgctcctata gggctaggct gttatacagc
     1081 tacaataatt ggggaacttg gaagtaaaat aattcaagga tatgtaaggg tgtttgtaat
     1141 ttattcacta acagcagcca tgtatttctt attattttac agtctgtatg cttttttatc
     1201 tgcaggaaaa caagggttta gacaattctg gagaaatgct ataaaaccaa tagcaacggc
     1261 actagctact tcttcaagtt cagcatgtat accatcaaat ttagaagcta gtaaaaatat
     1321 aggagttcct gatgatatat cagaaacagt tatacctctt ggaataaata tacataaaga
     1381 tgggtcagtt ttagcagtaa taataaaagt ggcattttta tcaggtattt taggtagtgg
     1441 aatggcaaat ccagcaacga taggtcaatt atttataact gtatttgttg ttggagtatt
     1501 tatggctcct gtagcaggtg gctgacttat tggtgagatg ctcgtggtta gcatcttcgg
     1561 ttttccagtg gaggcaattc cactgttaac agttataact actataactg atattcctaa
     1621 tactatatta aatacaactg gaaatacagt atcatcaatg ttagtttcaa gattagtaga
     1681 aggaaaagat tggcttatag ataaaacagc aattactaca aagaaaataa gctaattgta
     1741 cacttaatta ataaagttaa taggtatctt aattttaata aattagatac ctattaactt
     1801 tttaagtaaa aatataaatt taagattcaa atatgatatt tataatttga atcaactaat
     1861 atagtatata ttgaaataaa tatgtttaaa tatctatttt attttttaaa ataaaagatt
     1921 tcaaatttat ttttgttaaa agataacaag ccttcatctc gcatcttgcc aagctctctt
     1981 gacatagaac ttctgtcaac acataaaaaa tcagccattt catttcttga aaagggaatt
     2041 gtaaactggt ggctacctgt ttgttctatc tgttttgaaa aatacataag caatttctcg
     2101 cgagttgttt tacgagaaag taattctatt ttattgtgaa gtaaaatgtt tttttcagct
     2161 attaattgta gcatattttc aacaagccta ttatgaaata cacatgcaga tgaacaaata
     2221 ccagttacac ttttaaactt tataaataaa acttcgcaag aagatgttgt ggttactgta
     2281 acattacttt tatgtagtct agtacatgcg aatacctctc caaataaatc tccaggcaag
     2341 agttcagcta caatattcct attcccttcg atatcttcct ttattatatg agcacttcct
     2401 ttaagcataa ttccaataga agtaacttca cttccaacag agaatattat actatctttt
     2461 gggtaagtct tatctacaac acctaaacat tccaacattt cttcaagttc atcactttta
     2521 attccttcaa atagaggaat ttttttaagt aggtctatat gcttttctaa aaattttttc
     2581 aaataatcac ttccttgttg catatgcaac cgataatttg ttttcattgt actatactaa
     2641 gtttataaaa gcaaggggat ataaaaatcc tactacaaga aatttgaaat aaagaaatat
     2701 aggtattaaa aataaatata taagaaatca atactttaaa ttaaaaaaat tttatgaggt
     2761 gatataaatg atgagaaaaa taattaaaat tgatgaggaa aagtgtaatg gttgtggact
     2821 atgtgttgaa gcttgtcatg aagaagctat aggaatggta aatggaaaag caaaactttt
     2881 aagagatgac tattgtgatg ggctgggaga ttgtctgcca acttgtccaa caaatgcgat
     2941 ttcatttgag tatagagaag cagcagaata tgatgaagct gcagtaaaag caaatatgga
     3001 agcaaagaaa gcacaaaaga aaactttagc atgtggatgt ccaggttctc agtctaagtc
     3061 aataaataga gaggtttcaa atagtacgtc tataagcaat gatatagtag agataaaagg
     3121 ttctcaactt aatcaatggc cagtacaaat aaaattagta ccaactaatg catcatattt
     3181 aaagaatgca agtcttttaa tagcagcaga ctgtacagcg tatgcatatg gaaattttca
     3241 taataaattt atgaaaaata aggttacatt aatcggatgc cctaaacttg atgaagttga
     3301 ctatgctgaa aaacttacag agattttaaa agaaaatgat attaaaaata tagtagtaac
     3361 acgtatggaa gttccttgct gtggtggtat agtaaatgct gttaagacag ctctacaaaa
     3421 tagtggaaaa atgataccat ggcaaatagt tactatatct gtagatggaa aaattgtaga
     3481 tggagaaatt taattaagtg aattatagaa aaatataata aattttaata aataaaaagg
     3541 gaggaataaa aaatggaaaa aatgttttgt tttcaatgtg aacaaacagc aggaggtaaa
     3601 ggttgtacta taaatggtgt ctgtggtaaa aaggggggta cagctaactt acaagacgaa
     3661 cttacaggag tgttgattgg tctttcaaga gcaactattg gaaataagaa tagaccaaca
     3721 agtgaaacag ataaaattat gatagagggg ctattcacta ctataacgaa tgtaagtttt
     3781 gatgatgaag ctataaaaag acaaattgaa aaaactgagg tagaaaaaag taagcttgta
     3841 cctagatgtt cagattgttc aacaacttgt aatagaaatg ataactatga tatgaaggat
     3901 ttatggaatg ataatgagga catacgttca ttaaaatcat taatcttatt tggattaaga
     3961 ggtatggctg cctatgcata tcatgcaatg gtacttggtt atacagacaa agacgtaaat
     4021 gaatttttct atgaaggatt aatagcagtt ggaggagact tgtctattga cgaactttta
     4081 ggtctagtta tgaaaactgg agaaataaac ttaaaatgta tggaattgct tgatagagca
     4141 aatactgaaa cttatggaac accagaaccg actcaggtat ctatgaaaat cgagaaaggg
     4201 ccatttattg tagttacagg acatgacctt tatgatttac acaaattatt agaacaaacg
     4261 aaagataagg gtataaatat atatactcat ggtgagttat taccagcaca tgcatatcca
     4321 aaactaaaag aatataaaca tctaaaaggt aattttggta cagcatggca aaaccagcaa
     4381 aaagaatttg ataatattcc tgctccaata ttatttacaa caaactgttt aatgcctgtt
     4441 aaagatagtt atagagatag agtatttact acagaagtag ttgcttatcc aggtatggtt
     4501 catattgatg aagataaaga tttttctagt gtaatagaaa aagctcttga acttggagga
     4561 tatagagaag atgttcatat gactggtatt aatggaggag atacattaac tactggtttt
     4621 gcaagaggta cagtttcatc tgtacaagat aaagtagtag atgctgtaaa gagtggagct
     4681 ataagacact ttttattggt tggaggttgt gatggtgcaa aacctggaag aaattattac
     4741 actgaatttg taaaacaagc tcctaaagac actgttatat tgacacttgc atgtggaaaa
     4801 tatagattta atgatttaga ccttggggat ataggtggct tacctcgttt aatggatatg
     4861 ggacaatgta atgatgctta tagtgcaatt aaagtggcag tttcattggc aaatgctttt
     4921 gaatgtggag taaatgattt gcctcttagc atggtactgt catggtatga gcagaaagct
     4981 gtttgtatac ttcttacact acttcattta ggtatcaaaa atatctatat agggccttct
     5041 ttgccagcat tcttatctaa gaatgtatta gatatattgg ttgataaatt tgcattgaca
     5101 cctatatcta ctcctgaaga agatatgaag aagattttag gataaataaa tatatctata
     5161 cttaaagata tttatagtta aaatattttt aagtatgcca caattaagat aaggggttaa
     5221 acttaaaatt tgattaaaaa atcaattttg agatgaccct ttatttattt tttgtaataa
     5281 ttgaaaaata aacctgcttt cagtatattc ttttaagaat ttttgtatta aatttataat
     5341 acttagatat ataatatctt atatatttta ttttaagtat taaaggtttg aatgtaactt
     5401 aaatattaaa agaggaacat tgtaatatgt aacttgcata aaatatatat actatagtga
     5461 aattattttg attaaaattt aaaatataag gtgttttatg tgggggtata tgtatatgaa
     5521 aaattctaat tttaatatat tggcatttga tggtggtgga ttaaaagggg cattgagtat
     5581 atccatactt gagaggatag taaaagagta tccaaatcta ttaaacaata taaatatgtt
     5641 tggaggtaca tctacaggga gtctaattgc actagggctt gcgtatggtg taagccctaa
     5701 agagataaaa gaactttact caattgaaaa ttcaaagtat atttttaata aaagttatgc
     5761 agaaatactc agaccaaagt atgaaaacaa aaacttaaaa gaagttttat taagtatatt
     5821 tccagaggaa ctagaattaa aagatttaaa taaattagta atgataccaa gtttttatat
     5881 aggaaatgag gaaaatgcat ggaaaccagt attttataac aatatgccaa attcttttac
     5941 aaagactagc aaagttgtag atgtagcaat ggcaagtagt gctgctccgg tattttttcc
     6001 aacatataat cgtcatgttg atggaggaat aatagcaact gacccgagtt tagcgtgtat
     6061 aattcatgcc attgatagtg gatttagact taagaataca agactttttt caatagggac
     6121 tggatatgta tataacagta taaaggcaga tactaccgaa tggggagcta ttgactggat
     6181 aattaataaa gaacctgatt taccaattat atctattacc ttagaaggaa attctcaaat
     6241 gagtcagtta ttttctcaaa aacttcttgg agataattac tatagattaa atcctaagat
     6301 ggaaaaagat gtagctatgg atgattgtga tgcattagaa tatctaatgt ctttaggaga
     6361 aaattgtgat ataaaagatg cttttggatg gataaagaaa aagagctttt atagaaatta
     6421 gattcaattt gcaattgtat ttttacacat gatttcattg agtaggtaaa aataataaaa
     6481 tgcagattat taagttactt cttagggaat aaataaagta taatttattt aaggagtgat
     6541 gaaaatgata aaacttgcta cttttgcagg tggatgtttt tggtgtatgg taaaaccttt
     6601 tgataagtat gatggagtta ttaaagtagt ttctggatat acaggtggtc atgttgaaaa
     6661 ccctacatat caagaggtat gttcaggaac tactggtcat ttagaagcaa ttcaaataac
     6721 atatgatgat gatataataa gttatgatga acttctaaat atcttctgga aacagattaa
     6781 tcctacagat gatggtggac aatttggtga taggggaact caatataaga ctgctatatt
     6841 ttatcatgat gaagaacaaa aaaatatagc tttagagtca agagaacatc tggaaaatag
     6901 taaaatattt gatagtaaaa tagtgactga tataattcca gcaactaaat tctacgaagc
     6961 agaagaaaat catcaggatt attataaaaa aagaccatta aactacaata tgtattataa
     7021 agggtctgga agatataatt ttgtaaaaag tcattgggat ggaaacaata taaataggga
     7081 agagttaaaa aagactttaa ctcctataca atttgaagtt actcaaaatg atatgacaga
     7141 agtacctttt gaaaatgaat attatgataa taacaaagag ggaatttatg ttgatattgt
     7201 aagtggagaa gtgttatttt cttcaaaaga taaatttgat tctggatgtg ggtggccaag
     7261 tttttcaaag ccagttatag ataaatctat cattgagaga agtgatttct cacaaggtat
     7321 gtacagagtt gaagtaagaa gtgctaaagg aaattctcat ttaggtcatg tatttgatga
     7381 tggtccaaaa gaacttggag gtttaagata ttgtataaat tctgcttctc ttaaatttat
     7441 accaagagaa aatatggaag ctttaggata tggagaatat ttaaaacttt ttgagtaatt
     7501 aggaatattt attataaact tatctaaaag gtgaaaatat aaaaaaatat tttcaccttt
     7561 tgtttttttg tcaatagtat gataaattat taattgtaat cttatttata ccaatagatt
     7621 aagaatttaa ttttgaaaga gagaaaacaa atgaatttaa aagactttaa tggaaagaga
     7681 ttaaaatcag ctagaatttt tagagcaaag acgatagaac agttgtctaa agaaactaaa
     7741 ataaataaaa aagatttaaa agcttttgag gaaaataagt atgtaccaaa tatagaaaat
     7801 acattaaaat tatctaatat attaaatttt ccaaaagagt atttttataa aaatgaaaat
     7861 ataaatatcg ttgtagagga tagccacttt aaccctcaat ctaaactacc tagagtagaa
     7921 gagatttctt atagagaaaa aataattata atacataaaa tatattcatt tatggagaat
     7981 tatattaagt ttccaaaaga aaacttgcca aatagaaaag taatgtcaga tattaatata
     8041 aatgatatag aatctcttgc atataagact agagagtttt gggatttaaa tagtactcca
     8101 atagtaaata tggtaagttt gttagagtct aaagggatta taatatcagg tatgaatgta
     8161 gatagaaaag gggcaactat ctttactcaa aaacagagaa ttagtaaaga atctaaatat
     8221 ctaatatctc tgggtaatga caaaaagtca gcatcaatta gaaattatac tttggcatgt
     8281 gagcttggat atataatatc aagtgaatta agaataccaa gtaagcaatt ttcagaagat
     8341 gagtatgcct gtgcattttt attgccaaaa gagagttttt taaaagattt gactcatcca
     8401 gaagatttag attattatgt agaactaaag aaaaaatgga ttgtacctat atctgctatg
     8461 atttttagag catataatct agaaaagata aattacaaaa aatacaatta tcttatgaat
     8521 gaaatggata aaaaaggctg gttgatagaa gaaccactag acaaaatgaa aggttcaagc
     8581 ccaacgtatt taaaaagagc agttgaatta ttgatagaaa ataaaataat gagtgtaaat
     8641 agtatagtat caagtttaga ggaatttgga ataaatcttt atccagaaga cttagaatta
     8701 ttgatgggat tgaaaaaagg attgttatct caagaggtaa ataaaaaaag taaagttata
     8761 aaatttgatg gtaaaaaata ggtttatatt ttagtattaa aattaaaagc aggtacaaat
     8821 gatttaaaca ttaacttagt taaaagtctt ttcaataagt catttacctg cttttagtgt
     8881 aagaaagaat attgaatcta aagtgttttt gaaagtgcaa tatattccct taaaacagaa
     8941 caagatttat taaattcgtt ttgctcatat tcagtcatat tgatttcaat aatttcttca
     9001 ataccatctt ttcctataac acatggaaca cctgcaaata catttctttc gttatattga
     9061 ccttctagta atgtagaaac tggaagaact tttttctcat tgtgtagtat agcttttaca
     9121 atttctacta aagcagtacc tataccaaat tctgtacaat ctttaccatt tattatactt
     9181 attcctgttt ttttattttt ttcaactatt gatggtaagt ctaaattgct ataagtactt
     9241 gggttgtctt ttatcatgtc taagattggt ttaccaccaa ttgaaacatg agaccaagga
     9301 accatttgag aatctccatg ttcacccata gaataagctt gaattgattg ttgagcgatt
     9361 ccagtttctt cagataaaat ccttctaagt cttgttgaat ctaaagctgt tccagttcca
     9421 atgactttgt ttttaggaaa gccagatttt tcccaaatat aatttgtaac tacatcaaca
     9481 ggattagata tgactacaaa tataccatca aagccagaat caactatggg ttttactata
     9541 gattttatca ttccaatagt tggtcttagt aaatctaatc tagttgtgtt ttgtctacgt
     9601 aaaggccctt ctgaagagtc tgcaacactt atcactacta tgtcagaatc tttacagtca
     9661 gaaaaagttc ctttttctat atgtacttta tgtggcagat atgaaactgc atcagctaaa
     9721 tctaaagctt gagcttttga tttagattca tctatatcaa tcataaagag ttcatcacaa
     9781 actccttgag ttattaaact aaatccacaa tgagaaccaa catgccctga acctacaata
     9841 gatatttttc ttggctttat tgccatttta aatcactccc cctaaaataa cgatacattg
     9901 aaaattatag atgttattaa aagctgtttt tgaatatttt aatattctat tatttcagaa
     9961 aatttattta atatgatttt atactaaaat ttttaaaaaa gcaatgttaa tatactctct
    10021 attagtgaat attaaagtat tatatgtata ttaataatta ttaaaatatg taatgtcact
    10081 gatagttaga atatttaagt gataaaagat gtgtataaat aataatgatg tcagtttata
    10141 atgatattaa attgaggtat actgtttctc taaattaaaa aataaaggag taaatgtgtt
    10201 atgaattatc atacaaaaga agaattggtg gaagcactga gagtaatatc ttcaagtatt
    10261 attaattgtg aaaaaggaca gaagaaattt tctgaggaga catctcatca tacatgtttt
    10321 aagaatatta tagaagcaat atatatttca aaatcattaa taatggatga aattagtaaa
    10381 agagattgaa gcttattttg caatttaaca tgttttaata tacattttat tatataagaa
    10441 aataagtaaa tatacatgtt ataaaatatt ggaataatat acaattataa atttgttaac
    10501 attaatatct atatgttaaa atatagtaga agatgttagt aaataatagg atgagttcta
    10561 ttttaataca attaaattaa gcttagtttg aaatttgtat ctaaaaagta aagtaatcta
    10621 gaattaagaa aatggagata gaattataat ggaaaaatta tattatacaa atcagtatat
    10681 aagagatttt acagcagaaa taattgaaat aaaagaagta gaaaataagt atcatgtttt
    10741 attagataag acagcttttt ttcctggtgg aggaggtcag tttggagacc tgggaaaaat
    10801 agagaatgat gatgtaataa atgtgtatga agatggaaaa aaaatatacc atgtattaga
    10861 taaaaaacct ataaagatac ataaggtaaa gtgtagtatt gattgggata gaagagaaga
    10921 tggaatgcat caacattttg gacaacatgt attgtctgga tgttttttta aaacttttaa
    10981 tgcaaatacg acaggttttc atttgggaaa tgagtatagt acagtagata tagaaggtaa
    11041 tttagaagag gataaaatta gagagataga gttgtttgcc aatgaaatta ttcgtcaaaa
    11101 tatacaagta gagacattac ttccaacgaa aaaagaacta aaaaagattt ggttaagacg
    11161 tgatttgcca aatactgatg aagagataag agtaataaaa ataggtgatt tagatacgaa
    11221 tgcatgttgt ggagtgcatc caaaatcaac tggtgaattg agaatgataa aaataaagaa
    11281 atgggaaaaa cataagtcaa gtacaagaat agagtttcta gcaggtaaaa gggcagtgga
    11341 tgaagtattg aagagggata tatatttgac taaaatatgt agatatttaa gctgtagtga
    11401 ggaagatgct ataaatggta ttgtaaatct aaatagtaaa gtggaagagg ctttaattaa
    11461 aaaaagaagg cttgaagaag tagtatctac atatcaggtc aaagaaatga ttgaaaaagc
    11521 aaataaggtt ggcaatattt cggtcattaa aaaaatttat gatgatgaag atttgaaata
    11581 tgtaaataag atagcaaata aaattgcaga atatgaaaat agtattgcat tattagctgt
    11641 taaatttaat gataaaataa atttagtttt tgcatgttct aaaaatttaa aagatattaa
    11701 tatgggagtt ttattaaagg atgcaataaa tcttatagat ggcaagggtg gtggaagtaa
    11761 agtattagct caaggaggag gtaagaataa tggaaattta gaggctacac ttgattatgc
    11821 atttatgaag atagaaaaaa ctctataaat atattatata aaaaacctta gtagataaaa
    11881 tagatatgga ggaataagta tggagcaaca aaaggactac atagagttat atgaaaatga
    11941 agaactaata gagataagag aagcacgtat ggatgatttg gatacaatag caaaatttaa
    12001 ttataatttg gctaaagaaa ctgaaggaaa agaacttgat atggatgttt taactaaagg
    12061 tgtaaaagca ttgttattag atgagagaaa aggaaaatat catgtatata cagtatttga
    12121 taaagttgtt gcacagatta tgtatacata tgagtggagt gattggagaa atggaaattt
    12181 cctttggatt cagagtgtat atgtagataa ggaatataga agaaaaggta tctttaatta
    12241 tttatttaat tatataaaaa atatatgtga taaagatgaa aatatagttg gaatgagatt
    12301 atatgtagaa aaagaaaaca taaatgcaaa agcaacatat gagtctttaa atatgtatga
    12361 gtgtgattat aatatgtatg aatacgaagt aatacattcg taatataaat ttgtaatact
    12421 gttatactga tgttataaag tattgattat attgacgatt atatgaaata aactggatat
    12481 tataattaga atttttaggg ggtataaaaa tgggcgtttt aaaaggaatg ttttatgtat
    12541 ttttattttt agatttagtg tcaatattct gtttcttttt taataaagga aaaatagcat
    12601 ctaataaaat tgtgtttaat gcaataggag tacttacatt tgtactttgt tttatgcttt
    12661 ttagttatta tcctaataat aatcttattg gaaaatttat tgcttctcta ttttttatat
    12721 ttggagttgc aggagttatg ttgaaagaaa aaaatttttt atatgctaga cttcttttaa
    12781 ctgtagttat agttttttct acattaagat tgttcgttat tcaataaaat gtatttgtat
    12841 gaaaatttat taaagtctac acatttaagt gtaggctttt ttgatttttt gtttgaaaat
    12901 taaggaaatt ttaaggaaat tttaaaatcg tcttaaatat ttattgatat acttaaaata
    12961 ttaatagcga aaggagactt atcagtgata gaaagtaaaa agtcagaaaa attgttactg
    13021 tcaattatat acataatatt tttggtatat attttaatga ttataagaat aattttattt
    13081 agagatgtac caatttacgc tattttcaag ggaacgttta ggaatgtaaa tttaattcca
    13141 ttttatacaa tatatcaatt tatagtagat agtaatcttg actttatgaa agctactgta
    13201 aatattatag aaaatatagg tatatttatt cctatgggaa tttttttacc tatagtatgt
    13261 aaaaatctaa ataaaaaaac tataattata gtaattatac ttgttagcct agcatttgaa
    13321 ttaacacaat atatttttgc tcttggaagt agtgatatag atgatgttat tttaaattca
    13381 ttaggtggca taattggaat taatatttac ataaacatga ataaattatt tcccaatgat
    13441 attaacagat ttaaggctat aataggtact agtttagttt taggagttat aggattagga
    13501 gttatttcta aaaattatca taacttacta acttttaaat ttagacctga tagaaaaata
    13561 tcaaaaatat taattgaaga aaatagggaa ataattaaag atataaataa agatacagta
    13621 gatatagttg ggacatttga gagctttaaa aaaggaataa taactattaa agcaggttct
    13681 aataacaaag taaagagacc agagaattta attgattctg atggaaatat aagaatttat
    13741 ttaaatgaaa atacaaaatt agtatcttat ataattacca aagaatcaaa aatggatata
    13801 gttaaatatg aggaatttga tgtgaagaat ttagatttat taaggagata tgatactatt
    13861 aatgtttgga ttgataaaga aaatcagcca aaggataaac atggtattat ggctagtaaa
    13921 ttattaattg gattgtatga ataaaatatt aaacaagaat aaaagaataa caaatataaa
    13981 aaacgaaaaa actatttcta taattatttt tacgttgtgc ataaaataag aacattagtg
    14041 aaggagtaga gataaattat ggagataata aaatatatct tgtacttttt tatatattca
    14101 tttttaggat ggacagtaga aagtatagga tgttctatag caagcaaaag aataatcaac
    14161 agaggttttt taaatggtcc aatatgccct gtttatggtt ttggagcggt aattgtgata
    14221 tcactattgg gaagatttaa taatgtagta atagtatttc tattaggaat gattttaact
    14281 acgatactag aatattttac aggatttatt ttagaaacct tatttcatgc taaatggtgg
    14341 gattattctg acagaaaatt caatataaag ggtagagtat gtttaaaaaa tgcaatatac
    14401 tttggtgtaa tgtctgtttt aataataaga tttatacatc catttataaa atattttgta
    14461 agtataattc catatagaat attaatttca atggctataa ttacaacact ttggactata
    14521 cttgatttga ttgttactat tataacactt aaaaaattag atataaagtt aaacttatta
    14581 gacgatataa ttacagacct taatgatata aatgtgaaat tggataaatt tgatagagga
    14641 gaaatacaag ctttatttaa aacaataaat aacgacgaat tagaagttag agaaaaaata
    14701 aacaaaataa atagtaagtt ggaccgtata gagtctaata ttattttaca aaaaagagtt
    14761 ataaaagctt ttccacatat aaaacataaa aaacaacaag agcaactaga acattttaaa
    14821 aaaattatta atgagaaaag gtaattatac aatttaatga agacgaatag aataatggta
    14881 tttataagat gattttcaga ggactctata aaaatagaat agagtccttt attttttgaa
    14941 aaataatgtt tatttgataa aaataaaata tattgtttct gaataacaaa tattttgaaa
    15001 attataaaaa catatattga caatttgtgt caaaaatact aacattaagt atataaagaa
    15061 ttttatatga gaatatcttt ataaatcgca ataattttaa aacataaatt tatttaaaga
    15121 ggggatgatt tgccaatgag cgagataact agtcaaatga taagtacaga agaaaaaaaa
    15181 tatgttgcta aaactcaaaa gataccttat tatccagtag catttaaatc aggtgatggt
    15241 gcaatgctat atgattatga aggtaatgaa tatgtagatt ttttagcaag tgcaggctct
    15301 gcaaatgtag gtcatggtaa taaggaaatc tcacaagcag ttaaagaaca aatggatgat
    15361 ataacacaat atacacttgc atatttccat agtgatcctc ctgtaaaatt agctgagaag
    15421 cttgtggaaa tagcccctgg agataatgat aaaaaagtac tatacagtgc aactggttct
    15481 gcttgtatag atgctgctat aaaattagca agagggtata ctggaagaac aaagataata
    15541 tctatgtgtg aatcttatca tggaagtact tatggagcta tatctatatc tgctttaagt
    15601 acaaatatga gaagaaaaat gggtccattg ttaccagaag tttatcactt ccattatcct
    15661 gataaaaata gaacagctaa agaatgttta gatgagatag aatatgcttt tgcacactat
    15721 ctaccagcag aagaggtagc tgcaatattt atagagccaa ttgcaggaga tgcaggaata
    15781 atagtgcctc cagtagagtg ggtacaaggt ttaagtaaaa tatgtaaaga aaatggaata
    15841 ttacttgtaa gtgatgaaat acaacaaggt atgggaagaa caggtaagtg gtttggtata
    15901 gaaaattttg gtgttgaagc agaccttata gttcttggaa aatctgttgg aggtggatta
    15961 cctctaggag cagttgttgg aagaacagaa ataatgcaaa gtcttgatgc accagcacat
    16021 ttatttactt tagctggaaa cacaacagta tgtgtggctg ctttaaaatc tatagagata
    16081 attgaaaaag aaaacttact tcaaaagagt atagaaatgg gagattatat taaagcagga
    16141 tttgaaaaac taaaagaaaa atacgatata attggagaaa taagaggcat aggattatct
    16201 ataggagttg atatagttaa aggaaaaggt tctaatgaaa aacatccaga tgctacagct
    16261 aagatatgtt atagatgtat acaaactgga ttaataatga tattcttagg acaatctact
    16321 ttaagagtgc aaccacctct agtaataact aaggagcaag tagataaagc aatgaatatc
    16381 atagattctg caatagatga ttatttaaat ggtagaattg gtgatgaagt atatgaagta
    16441 actcaaggtt ggtaaaataa atattaaatg aaaataggag ttatctcaat tttagaaaat
    16501 tatttctgaa aagagataac tcttttaagt tacccacaaa taagaaaatt gtttgattca
    16561 ttaaagacta tatttcggat gtcgtttttg tgagtatcag agacagtatt acgagaataa
    16621 ttacctttat tcgtactatc tgttaattta gttataatta agatagctaa aagaataaga
    16681 attactgtgt ataaagcaat aacatatggt tttcttttat atttgtattt gttattgaaa
    16741 aaagaatggc cataattatt tttatttact ttagatgtac ttgtattctt tttcttgtta
    16801 cctttctttt tatcatcctt ttttctattt ttagggtaag gaatgacttt gtgtgtatta
    16861 tcaagtttga tatttttatt tttttgaata ttgttttcca ggctagcctt tttttctcca
    16921 aattgaatag ttttattggt attgttgtta tctttcaatg ttaatctccc tcccttaaac
    16981 tttcccttta gataatatta ctactaacct atggaatata caataaataa tatataagta
    17041 ataaaatttt ataggtataa atctctttct ccacgctcta aggcagtcat attgttagat
    17101 actatgtttc ttatatcttc tctttctatc ttacctattt cttctgcgat aagtttttta
    17161 cccataattt taagttcttc atctccataa tcgattaaaa attcatttaa tgtagtaaga
    17221 gcatttggtg tacatacatt atggatttgt cgacttttag ctaagctcat gaatctatcg
    17281 ccagttctac ctttacgata acaagctgta caataactag gtatatatcc atcagtaatc
    17341 agttctttaa gcacctcaac agggcttcta tggtctccaa cttcaaattg ttctgtattg
    17401 tcaccatctt catatgcttt atatcctcca acacctgtta gagaacctgc actaatttgt
    17461 gatacaccat attttagtaa ctcatttctc atttcagcag tttctctagt ggacattatg
    17521 attccagtaa aaggaacagc caatctagtt atagctacta tttttttgaa catatcgtca
    17581 gaaactaagt gaggaaaatc ttctaagctc ataccttcag cttttttcaa tctagggaaa
    17641 gatatagtat ggaaacctac accaaatttt tcctctaagt gttcgttgtg catcataagt
    17701 cctagaactt caaatttagg gtcagataaa ccaaataaaa ctcctgcacc aacatcatca
    17761 acaccagctt ccatagctct atcaaaagct gttaaatggt aataatagtc attttttata
    17821 gattgaccat gcatttttat aaatgttggt ttgtgataag tttcttggaa taatatataa
    17881 gttcctattc ctttttcttt tagtaattta tactcatcta cacttgtagc tgctatgtta
    17941 acgtttaccc ttcttatatt tccgttttca ttatatgttg aataaattgc atctaagcaa
    18001 tctaagatgt aatttatatc acaattttta gggtcttcac cagcttctag agcaagtctt
    18061 ttatgaccca ttttttctaa tattttaacc tcttccttta tctcttccat ggtaagtttt
    18121 tttcttttaa atttgttgca tttactaaaa ccgcaataaa cacattcatt tacacagtag
    18181 tttgatacat aaagaggggc aaataaaacc actctattac catatatttc attttttatt
    18241 tgcccagcta tactaaataa tctatctagt tgttttttat cttctacttc aagaagtgta
    18301 gctatatctt tataactaag tttttccctt ctatcagcct tatcaagtac cttttcaata
    18361 tcatcagaag ttgaattttt tgcatcttct aataaagaat taataagttc atggtttatg
    18421 aacatttaca aacgcctcca ttcaatatta tcaccgcgag aatagtcaac ttcaagtcct
    18481 aatgacttga tgttttcttc taaactttgg tgatattcac aagcttcttg accagtaaag
    18541 gctttgttat cgtaaagaga atattgtttt ctaaattctt gaggagaaag gtttggcata
    18601 attacattgc aaccagctaa aagacctgca tttctaccac tagggtttat agatgccaag
    18661 gctgttgtag cgggtaataa aacttttgga agtagaagtc ttgtaattga aagcataagt
    18721 aatgtcttct ctaaatctcc atgtttataa tccttaaaaa ttgtatcatg gtgtggaata
    18781 aaaggtccta ttccaaccat atgaggattt aactctttta ggtataataa atcacgaaca
    18841 aggtcttcgt tgttctgaaa tggtgattca accataaatc cagcacctac ctgataacca
    18901 atttctttaa ggttttttag gcattctttt ctagttctaa gctcaatgtt tggcggatgt
    18961 aattttttat aatgactgtc tgtagcagtt tcatgtctta aaagatatct atctgcacca
    19021 cataaaaagt attttttata cgaatcataa ctcttttctc ctagtgatag agttatggca
    19081 caatcctcat atttattttt tatacttgaa acaatttcac atattttatc atcagtaaaa
    19141 tatgcatctt caccaccttg caaaacgaat gttctgtatc ctattttata acctatatca
    19201 caacattcaa gtatttcatc aagtgaaagc ctgtatctta tgatattttt attagaagat
    19261 tgtattccac aatagtagca attattttta caatagtttg taagctctat aagtcctctc
    19321 aagtagactc tatttccata atgtttattt ctcatgtcgc tagcttgttt ataaagatag
    19381 tttcttaaat tttgttcgaa gttatattcc tcattgtcga tattttctat taaatatagt
    19441 agttcatcaa aacttaatga attaatgctg taaagtttat ctataaagta tttaatctta
    19501 tttttagtca tattcaaata tgtaattatt aagtatagtt aaatttttaa taattgaaaa
    19561 gttcaagtga tctttccaaa atacctttta catatgctat taagacacca tagtttacaa
    19621 taggtacatt gaaagatttt gccttttcta ttctagataa cattccagct ctattcatca
    19681 tacaagctcc acagtgaact acaagggcat atttatttat atcttcagtg aaggatactc
    19741 cagaactaaa ttcaaaagta atgtttttgc cagttttctt tctaatcata ttaggaattt
    19801 ttactgttcc aatatcatca gtttgtctat gatgggtaca tccttcggcc atcaagattt
    19861 tatcaccatc ttttaaattt tctaaagcat aagctccatt aatcaattct ttaaggtctc
    19921 ccttttgtct agcaaacaat atagaaaaag atgtaagagg aatatctttt ggtgtatctt
    19981 tatctacttg tggaaatact tgagagtcag taataacaag ttttggtttt ttgcctaaat
    20041 tagatagagt ttcttttaaa ctatcttctt ttgtaactat agaaattgca ccattatcca
    20101 aaatatctct tataacttgc tgttgaggaa gtataagtct accttttgga gctgctttat
    20161 ctattggaac aactaaaaca actaaatcat ttggttcaat taaatctgat accaatttga
    20221 actcagtgct atccttaggc aaaactttta ttatttcatt ttttaaattt tcaattccaa
    20281 ttttatctgt tgatgagaca gaaacaactg gacatttaac tttattttta gttaagttta
    20341 aaatttctga ttgattctta atagtatcaa ttttgttaag aattagaata tgagggatat
    20401 tcttatcatt aaatttttca attagtgaca aatcttcttg tgatatacca atttggcaat
    20461 ccactactag taaagctata tctgtctttt ctaaaacatc tagtgattta cctattctaa
    20521 gttcaccaag ttcaccaaca tcatcaagac cagcagtatc tataagaaca caaggtccta
    20581 taggaaggat ttccattggt ctaaatactg ggtctgtagt agttccagca atatctgaga
    20641 ctattgcagc actttgattt gttatagcat ttattatgct agatttacct gcatttcttt
    20701 taccaaagag acctatatgt actcttaccg attgtggagt agaatttaga ctcatttgta
    20761 ctcaccacct taaacttctt tttttgatat actagttttt acagatacat gaggtatgtt
    20821 gcccaattta ccagtcaaac tattaatagt atccatttcg ccaacaactg ctatacatac
    20881 gattgagaca ccttcttctt cgcaaggaat gcccattctt cctttaataa tacctttaaa
    20941 acctgataca acctcattga atttaaattg acattctttt ggctcttcca aaatagcact
    21001 tataactgca acctttttca taaatatcct cctaactcag aaaatatgtc ttaaacaaat
    21061 ccaaaatcaa aaaacttttc tttgtaaaga aaagtttcta caaaagaaaa gttattaatt
    21121 acacaagtat aatgtgctat attaaactat ttccttacag attagataac tcttttctgg
    21181 tagggttagc ttgtaaaaat ttaatttaac aacaagtaac tgaagaaaat ttttatacaa
    21241 tttatataaa ttataataaa aatt
//
LOCUS       DAMJXI010000063        20828 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.065, whole genome shotgun sequence.
ACCESSION   DAMJXI010000063 DAMJXI010000000
VERSION     DAMJXI010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20828
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.065"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            80..1198
                     /locus_tag="PC465_002924"
     CDS             80..1198
                     /locus_tag="PC465_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2650209.1"
                     /translation="MIAVKKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KSDKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALKDLDNAYKKFFKEKAGFPKF
                     KSKKINRFSYKTNFTNGNIMYCGQYIKLPKLGMVKIRDKQVPQGRILNATISKEPSGR
                     YYVSLCCTDVDIEVFENTNNHIGLDLGIKEFCISSCGDFIENPKYLKKSLNKLAKLQR
                     ELSRKTIGSLNRNKARLKVAGLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNM
                     IRNRKLSRLISDVSWSEFIRQLEYKANWYGRKIVKVGKFFASSQICNKCGYKNEEVKD
                     LNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
     gene            1316..1621
                     /locus_tag="PC465_002925"
                     /pseudo
     CDS             1316..1621
                     /locus_tag="PC465_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
     gene            1634..2539
                     /gene="truB"
                     /locus_tag="PC465_002926"
     CDS             1634..2539
                     /gene="truB"
                     /locus_tag="PC465_002926"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HDF2650210.1"
                     /translation="MNKIISILKPTGMTSHDVVSRVRKILNIKKVGHTGTLDPDASGV
                     LPICIGKATKVCEVILNKDKSYICELTLGISTDTYDASGEILKKVDDFKFSNEDIERA
                     FDTQRGEINQLPPIYSALKVNGKRMCDLVRSGRQSEITLKTRRVNIKDIKILSIKGNK
                     VMFYVECSKGTYVRSICHDIGEYLGCGAHMSFLNRTSSGKFDLDNSITLEELELFYEN
                     KTLDKYLYDIDYVLDSFNYVVLNPNAIKYYCNGGSIDDKRFLKNNFDKDDEFVRVYST
                     DNFLGLGKLSKHNNTISVKSDKMFI"
     gene            2670..3599
                     /locus_tag="PC465_002927"
     CDS             2670..3599
                     /locus_tag="PC465_002927"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HDF2650211.1"
                     /translation="MVIIKSIKEIANIKESVITIGNFDGVHKGHQVLIGKTVEHAKKE
                     NIQSIVFTFANHPVNYFRPNSTKNIISNDDKIKLLEDLGIDIVVIIPFDEYMTKIPAK
                     DFVDEILVKKLKAKKIVIGHDFTFARAKEGNVNLLKSLEHEFGFEVEVIKPIKINDVR
                     VSSTYIRSLVSQGDMANVKEYLGRNYKLEGCVIHSKHLGRTIGFPTANIDLKNNMLVP
                     KRGIYASIVHIGDETYFGATNVGYNPTVNGKTLSIETNILEFDRDIYGENIIVEFLER
                     IRDERKFNSIDDLKNQLYNDTNYVYENYVCKNK"
     gene            3703..3960
                     /gene="rpsO"
                     /locus_tag="PC465_002928"
     CDS             3703..3960
                     /gene="rpsO"
                     /locus_tag="PC465_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HDF2650212.1"
                     /translation="MINKSEIIKEYGRAEGDTGSPEVQIALLTARINELNGHLKTHKK
                     DHHSRRGLLKMVGRRRNLLAYLKEKDLEGYRALIAKLGLRK"
     gene            4200..5045
                     /locus_tag="PC465_002929"
     CDS             4200..5045
                     /locus_tag="PC465_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDF2650213.1"
                     /translation="MKIKLVCDSLCDIPDEISEKDYIEIVPLTVIFNDREYIEGVDIK
                     KEEFYKKVKEIKQIPKTSQATYMEFKEVFDKFITEGYHIICMTGAANASGTFQSAMIA
                     KNDVNENEKIHIFDTRNLSLGSGQYVIKACELLEEGLGFEEIIDELENTRSSVRLLFA
                     PYTLDFLKQSGRVPVATALIGNMLNIKPIFFFDNGEAKLVNKVRGIKNIASKLVDIIL
                     EMNEGSLEGKIVTIGCGDNLHDCEILKDEVNKRIKARRVLFTRGGVSICSHTGPDILA
                     ISCSN"
     gene            5170..7281
                     /gene="pnp"
                     /locus_tag="PC465_002930"
     CDS             5170..7281
                     /gene="pnp"
                     /locus_tag="PC465_002930"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HDF2650214.1"
                     /translation="MFEHKIFKMDFAGRELSVEIGKICEMASGSCIVRYSDSMVMVNT
                     TKSAKPRDGIDFFPLSVDYEEKLYSVGKIPGGFLKREGKPSEKAILTSRLIDRPIRPL
                     FPKGFRNDVQVVATVLSVDQDCTPDIVAMIGSSIALSISDIPFNGPTGSVCVGLVDGA
                     FVVNPNAEQREKSSMHLVVSGTKEAIMMVEAGADEVPDEVMLDAILFAHQEIKKIVEF
                     IEGIVAEVGKEKMPVELYHAGEEITQLVREFATDKMKKAVQTFEKLERMENMDRVKEE
                     TLAHFEETLEDFEDFVGDIEEVLQDIIKEEVRKLIVHENVRPDNRKLEEIRPIWCETG
                     MIPRAHGSAIFTRGQTQVLNVATLGALGDVQKLDGLDEEENKRYMHHYNFPAYSVGEA
                     RPSRGPGRREIGHGALAERALLPVIPSQEEFPYAIRLVSEVLSSNGSTSQASVCGSTL
                     SLLDAGVPIKDMVAGIAMGLIKHDGKVAVLSDIQGMEDHLGDMDFKVAGTEYGITAIQ
                     MDIKIDGIDKEILQRALKQAKEGRIHILGEMRKTISQPKPELSPYAPKIVKMQINPDK
                     IKDVIGPGGKIITKIIDETGVKIDIEQTGEVFISGIEIDMIKKAQELINNIVVEPEVG
                     KTYKGKVSRIMNFGAFVEILPGKEGLLHISHIAHERVAKVEDVLNIGDEVEVKVTEID
                     EKGRVNLSRKVLLPKPEHKNK"
     gene            7547..8290
                     /locus_tag="PC465_002931"
     CDS             7547..8290
                     /locus_tag="PC465_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2650215.1"
                     /translation="MIMMVLNKSKLKKIIILILVVLLVLSGGVMVLKLFNNKPVFNLF
                     NGVDLPYERGTKDKSGYVALTCNIDLGWETEYVESILETLKKENVKITFNVTGKWAEK
                     NKDELLKIKKQGHEIGNHGYKHLDYSTLSYEDNYEQIETSKKIIEEIIGEKTKFFQAP
                     AGSFGPETVKAAKALGYTSIKWDADTIDWKYKDQPEVIIDRMKKKDIKDSSIILMHPT
                     NATTKCIDDIIAIVREKGLKPGKLSDVFK"
     gene            8448..9695
                     /locus_tag="PC465_002932"
     CDS             8448..9695
                     /locus_tag="PC465_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDF2650216.1"
                     /translation="MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGT
                     SHFIEHMMFKGTKNRTSKEIASSIDNLGGQINAFTSKECTCYYVKLIDEHINTGIDVL
                     SDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
                     ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDIS
                     EAKFNPCFISKNKDTEQVNLAMCLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIR
                     EEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLIKKEIENIRENYLTEKEIS
                     ESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINNVNINSIKKVVDK
                     VFNIENIGTCIVGRDVEKILHLD"
     gene            9730..9975
                     /locus_tag="PC465_002933"
     CDS             9730..9975
                     /locus_tag="PC465_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HDF2650217.1"
                     /translation="MNLSEIAGKEIVNLVTGERLGVIGECDLILDETTGGILALLIPK
                     EKGFFARRKDKSFLEVPWRNVKKIGNDMIIIEYEGYI"
     gene            9985..11208
                     /gene="dapG"
                     /locus_tag="PC465_002934"
     CDS             9985..11208
                     /gene="dapG"
                     /locus_tag="PC465_002934"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HDF2650218.1"
                     /translation="MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSA
                     MGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIDSVFF
                     TGQQAGIITSDEYSNAKIKYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
                     DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVI
                     HPRAVQLAKSGNITLAIKNTMNPTFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDS
                     VAQVKIKSAEEVFTEVLNEIEKKLITIDMINFFISEKAFVVEDADIKSLKEILDKFEL
                     DYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEED
                     MHTAVHAIHQQFYLK"
     gene            11321..12055
                     /locus_tag="PC465_002935"
     CDS             11321..12055
                     /locus_tag="PC465_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HDF2650219.1"
                     /translation="MKDYREDNERFDKDNCSEESSCEERECIKQFGTNEMPPQPPKDI
                     QCITIIGEIEGHFIGNPQKKATKYEHIIPMLYSIEESNDVKGVLVVLNTVGGDIEAGL
                     AIAELLNSTSKKVVTLVLGGSHSIGVPLATAGDYSFIAPTATMIIHPVRTTGLVIGIN
                     ETFEYFKKMQDRIIQFIIRTSNIKKDVLEKLMHEKDELVSDVGSVLIGKEAVDYGLID
                     EVGGLKEALKKLRELIKESEEEKNND"
     gene            12178..14589
                     /locus_tag="PC465_002936"
     CDS             12178..14589
                     /locus_tag="PC465_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDF2650220.1"
                     /translation="MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWI
                     PVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFY
                     GLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF
                     ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTT
                     INKKPGFFKGLMSKGLNNDDDEDEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGT
                     QSMPELDVLKELQKATNENPVVDTKPEKKVDIAKPNLNIEKTQPMSIVAEPVNEDYSN
                     YKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEI
                     QPSPGVKVSKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLE
                     SEEFNNFNSPLAMGLGKDVAGKIIIGDIGKMPHLLIAGSTGSGKSVCVNTLISSILYK
                     ANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRYKLFAD
                     AQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIV
                     ATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAA
                     KPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIETISKVNTSKGSDEDEFLSEA
                     IEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQ
                     NLEGE"
     gene            14592..15650
                     /gene="mnmH"
                     /locus_tag="PC465_002937"
     CDS             14592..15650
                     /gene="mnmH"
                     /locus_tag="PC465_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HDF2650221.1"
                     /translation="MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNE
                     HNEVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAAELALNYDNIVIYCARGGMRSGS
                     IVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
                     EKGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESIFFSKENYIFVESESK
                     RVGSVTVPNEIFEAMTREGHHILLECDIENRVDRLCRDYIYDKDEGNILILKECINKF
                     RKRLGNKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKYKYSKIINFNDTQKA
                     LEDVIDLYESILEGESEC"
     gene            15644..16978
                     /gene="rimO"
                     /locus_tag="PC465_002938"
     CDS             15644..16978
                     /gene="rimO"
                     /locus_tag="PC465_002938"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HDF2650222.1"
                     /translation="MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIV
                     NTCGFIESAKQESIDTIINFAELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVG
                     TGSYQNIDKILKELSEMHQIVSLNDIEFVFNEDLPRYISTPSYMAYLKIGEGCSNNCT
                     YCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELL
                     EELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRK
                     TTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDFVEEVKFDRLGAFAY
                     SREEDTPADRLPNHIDEEVKIQRRDTLMMIQQKISEELNDKKIGKTYEVLIEEQIEDN
                     VYTGRTQGDAEEIDSIVYVKSVDNLEVGEFVSVQINDAMEYDLMGDVLYELA"
     gene            16965..17507
                     /gene="pgsA"
                     /locus_tag="PC465_002939"
     CDS             16965..17507
                     /gene="pgsA"
                     /locus_tag="PC465_002939"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HDF2650223.1"
                     /translation="MNLPNKLTLFRIFLIPVFVLIMLLNVPNKFLIACIIFIIASITD
                     ALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVS
                     ILRAIAAADGKVIAAGNSGKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLL
                     TLYSGWEYLYKNKELFMSSK"
     gene            17795..18841
                     /gene="recA"
                     /locus_tag="PC465_002940"
     CDS             17795..18841
                     /gene="recA"
                     /locus_tag="PC465_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HDF2650224.1"
                     /translation="MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTG
                     AIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSCVASAQKDGGIAAFIDAEHALDP
                     VYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
                     GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKF
                     YSSVRLDVRKIDTIKQGDKVIGSRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLL
                     DIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEIDEKVRAFYNLNEEH
                     EESGTSVSKEIVEE"
     gene            19017..20558
                     /gene="rny"
                     /locus_tag="PC465_002941"
     CDS             19017..20558
                     /gene="rny"
                     /locus_tag="PC465_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HDF2650225.1"
                     /translation="MDFIDSVVMIVIGAAVGIIAGYFVRKNISEAKIGQAENLAKEII
                     DKAHHDSETVQKEKLLEAKEEIHKWRTEAERENRERRTEVQKYEKRVVQKEEVLDRKL
                     QNLESKEVNLSEKLKVVEKKEEEVEVIKTQQLEKLESISGITSDKAKEIILTNAERDV
                     RREMSIMIKEIESQAKEEADKKSREIIGYAIQKCAADHVAETTVTVVSLPNDEMKGRI
                     IGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLIADGRIHPAR
                     IEEMVEKARKEVDNIIKEYGEQAAFETSVHGIHPELIRLLGRLNYRTSYGQNVLKHSI
                     EVAHIAGIMAAEIGADIRLAKRAGLLHDIGKAVDHEMEGTHVEIGMDLLRRYKESKEV
                     IHAMSTHHGDYEPQTVEAVLVTAADAISAARPGARRETLEAYIKRLEKLEEIANSYEG
                     VEKSFAIQAGREIRIMVKPEAINDEEIHLLARDMTKKIEDELEYPGQIKVSIIRETRA
                     IEYAK"
BASE COUNT         8546 a         2116 c         3990 g         6176 t
ORIGIN      
        1 attgttcacc acagcattat ataatatatt aaatatgata aaatcattaa aaagtgtatc
       61 aaaaaacaat taacgtgagg tgatagcagt gaaaaaagcc tataagttta gaatgtatcc
      121 aaataaaaaa caacaagagt taattaacaa aacttttgga tgttgtagat ttgtatataa
      181 taaatatctt gctaaaagaa tagatgttta taaaagcgat aaagaaactt ttacttataa
      241 acagtgtagt tctgatttga ccaatttaaa aaaagaatta aaatggctta aggaacctga
      301 caaattttca ctacaaaacg ccttaaaaga tttagataat gcatataaaa aattctttaa
      361 agaaaaggca ggatttccta aatttaaatc aaagaaaatt aatagatttt catataaaac
      421 taactttaca aatggaaaca ttatgtattg tggtcaatat ataaaactac ctaaacttgg
      481 tatggttaag ataagggata aacaagtacc tcaaggtaga atacttaatg ctactatatc
      541 taaagaacca agtggtagat attatgtatc attatgctgt actgatgtag atattgaagt
      601 atttgaaaat actaataatc atataggttt agatttagga attaaagaat tttgtatctc
      661 aagttgtgga gactttatag aaaatcctaa gtatcttaag aagtcattaa acaagcttgc
      721 taaattacaa agagaattat cgagaaaaac aatcggtagt ttaaatagaa ataaagcaag
      781 attaaaagtt gcaggacttc aagaacatat agctaatcaa agaaatgatt ttctacaaaa
      841 actatctact aaattaataa aagagaatga tattatttgc atagaagatt tacaagtaaa
      901 gaatatgatt agaaatcgta aactatctcg cttaatttca gatgtatcat ggtcagaatt
      961 tattcgtcaa ttagaataca aggctaattg gtatggtaga aaaattgtaa aggtaggtaa
     1021 attctttgca agttcacaaa tatgcaataa atgtgggtat aaaaacgagg aagttaagga
     1081 tttaaatata agagaatgga tttgtcctag ttgtaatgaa actcacgata gagatataaa
     1141 tgcaagtata aatatattaa aagaaggatt aagactaata acgattcaaa ataaataact
     1201 tatgtaagaa ccgtaggaac tacggggata gcctgtggag aattagtaag acatatttta
     1261 atatgcaaaa ttctgtgaag caggaaccct gtgactttag tcatgggagg ttcagtcaaa
     1321 ggtatctagt atagttttaa ctcaagacat gatgaataga aataatatta gctttaatga
     1381 tgttgatgga ataacaacat atacaagaga cataaaaggt atagaagttg gaattttatt
     1441 taaagagaaa aaacaaaatg aaattaaagt gagttttagg tcaaaaaatt atgttgatgt
     1501 aagtgaaata gccaagttat ttggcggtgg tggtcatgta agggctgctg gatgtactat
     1561 tagagatagt attgataatg caaagaaaat ggtactagag gcagtgttaa aatcaattta
     1621 aggtgacagt aaaatgaata agattataag tatattgaaa cccacaggta tgacatctca
     1681 tgatgttgta agtagagtga gaaagatttt aaatataaaa aaagttggtc atacaggtac
     1741 tcttgaccca gatgcttcag gtgttttacc aatctgtata gggaaagcta caaaagtatg
     1801 tgaagttatt ttaaacaaag ataaatcgta tatatgtgag cttactttag gtataagtac
     1861 agatacttat gatgcttcag gtgaaatttt aaaaaaagtt gatgatttta aatttagtaa
     1921 tgaagacata gaaagagctt ttgacacaca aagaggagag ataaatcaac ttcctccaat
     1981 ttattcagct ttaaaggtaa atggaaagag aatgtgtgat ttagtaagaa gtggtagaca
     2041 atctgaaatt actttaaaaa caagaagagt aaatataaaa gacataaaaa tactaagtat
     2101 aaaaggtaat aaagtaatgt tttatgttga gtgttctaaa ggtacttatg tgagaagtat
     2161 ttgccatgat ataggagaat atctaggttg tggagctcat atgtcgtttt tgaatagaac
     2221 atcttctggt aaatttgact tagataattc aataacatta gaagaattag aattatttta
     2281 tgaaaataaa actttagaca aatacttata tgatatagat tatgtccttg attcgtttaa
     2341 ttatgttgta ttaaacccta atgctataaa atattattgt aatggtggct caatagatga
     2401 taaaaggttt ttaaaaaata atttcgataa agatgatgaa tttgtaagag tatacagtac
     2461 agataatttc ttaggattag gaaagttatc aaaacacaat aatacaataa gtgttaaaag
     2521 tgataagatg ttcatataac caatgtattt aaaaaaacaa caaaagagat agtactataa
     2581 taacttctat agtctatctc ttttacttat gctataatag tttgtgaata agttaagagt
     2641 aaattatatt ttagcgggga acatttatta tggtgattat aaaatctata aaagaaatag
     2701 caaacataaa agaaagtgtc attaccatag gaaattttga tggtgtacac aaaggacatc
     2761 aagttcttat aggaaaaaca gttgaacatg caaaaaaaga aaatatacag agtattgtat
     2821 ttacatttgc aaatcatcct gtaaattact ttagaccaaa ctcaacaaaa aatattataa
     2881 gcaatgatga taaaataaaa ttattagaag atttgggaat agatatagtt gtaatcatac
     2941 catttgatga gtatatgact aaaatacctg caaaggattt cgtagatgag atactagtaa
     3001 aaaaattaaa agctaaaaag atagtaattg gacatgactt tacatttgca agggcaaaag
     3061 aaggcaatgt taatctatta aaaagcttag aacatgaatt tggttttgag gtagaagtaa
     3121 taaaacccat caaaatcaat gatgtaagag tgagtagtac ttatattaga agtttagtat
     3181 cccagggtga tatggctaat gtcaaggaat atttgggtag aaattacaag ttagaaggtt
     3241 gtgttataca ttctaaacac cttggaagaa ctataggatt cccaacggca aatattgacc
     3301 ttaagaataa tatgctcgtt ccaaagagag gtatttatgc ttctattgta catattggag
     3361 atgagactta ttttggtgct acaaatgtag gctataaccc aacagttaat ggaaaaactt
     3421 tgtctattga aacaaatatt ttagagtttg atagagatat ttatggggaa aatataattg
     3481 ttgaattttt ggaaagaata agagatgaaa gaaagtttaa ttcaatagat gacttaaaaa
     3541 atcaattgta taatgataca aattatgtgt atgaaaacta tgtttgcaaa aacaagtaat
     3601 gtatgataaa atgattaagg aaaataacca ttactcggca tttgaatact ccaatcaatg
     3661 cttagtaata ggcgtttcta aaaaaatacg gaggtaatct aaatgataaa caaatcagaa
     3721 ataataaaag aatatggaag agctgaaggg gatactggtt ctccagaagt acaaatagct
     3781 ttattaacag ctagaataaa cgagttaaat ggacatttaa aaactcataa gaaagaccac
     3841 cattcaagaa gaggactatt aaaaatggtt ggtagaagaa gaaacttatt agcttactta
     3901 aaggaaaaag atcttgaagg atatagagca ttaatagcta aattaggatt aagaaagtaa
     3961 tttcattctt tataaaaaag caggtatagt gtatacctgc ttttttatag ttaattcatt
     4021 ataaagtaaa atagttaata ataaaagtag tttatatgtt ataaaaaatt ataaaatgaa
     4081 taatattggg taagaatatt aaaatagtat acaaatacat aatcaattta aaaggaaaga
     4141 caggataaat atagaaattt tataacagga taattagttg gaataaggag gatattattt
     4201 tgaaaataaa gttagtatgc gatagtttgt gcgatattcc agatgaaata tcagaaaaag
     4261 attatataga gatagttcca cttacagtta tttttaatga tagggaatat atagaaggag
     4321 tagatataaa gaaagaagag ttttataaaa aagtaaaaga aatcaagcaa atacctaaaa
     4381 cttcacaagc tacatatatg gagtttaaag aagtgtttga taagttcata acagaaggtt
     4441 atcatataat ctgtatgaca ggggctgcaa acgcatcagg aacttttcaa agtgctatga
     4501 tagctaaaaa tgatgtaaat gaaaatgaaa aaatacatat atttgatact agaaatttat
     4561 ctctaggtag tggacaatat gttataaagg catgtgaact tcttgaagaa ggactgggat
     4621 ttgaagaaat tatagatgaa ttagaaaata ctcgcagtag tgtaagattg ctttttgcac
     4681 catatacact tgatttttta aagcagagtg gaagagttcc agttgcaact gctttgatag
     4741 gaaatatgtt aaatataaag cctatatttt tctttgataa tggggaagct aagttggtaa
     4801 ataaggttag aggaataaag aatatagcaa gtaaattggt cgatataatt ttagaaatga
     4861 atgaagggtc tttagaagga aaaatcgtca caataggttg tggagataat ttacacgatt
     4921 gtgaaatatt aaaagatgaa gtaaataaaa gaataaaagc aagaagagta ttatttactc
     4981 gaggaggagt ttctatttgc tctcatacag ggccagatat attggctata agttgttcta
     5041 attagtagta atataaggtt tttgcatata tatgtgaata taattttata ttgttaattt
     5101 atagtatttt tgataatata gtaaatagag tgatatacgt gttttttaat aagaggagga
     5161 caagcattaa tgtttgaaca taaaatattt aaaatggatt ttgcaggaag agaactttct
     5221 gtagaaatag gaaagatttg tgaaatggct agtggtagtt gtatagttcg atacagtgat
     5281 agtatggtaa tggtaaatac aactaaatca gccaaaccta gagacggaat agactttttt
     5341 cctttaagtg tggattatga agaaaaatta tactctgtag gtaagatacc tggaggtttt
     5401 ttaaagagag aaggcaagcc ttcagagaaa gctatactta catcaagatt gatagataga
     5461 ccaataagac ctttattccc aaaaggattt agaaatgatg ttcaggtagt tgcaacagtt
     5521 ctatcagtag accaagattg tacaccagat atagtagcaa tgataggttc ttcaatagcc
     5581 ctttctatat cagatatacc atttaatgga ccaacaggtt cagtatgtgt tggccttgta
     5641 gatggtgcat ttgttgtaaa tccaaacgca gagcaaagag aaaaaagttc aatgcatcta
     5701 gttgtttcag gtacaaagga agcaataatg atggttgaag ccggagctga tgaagttcca
     5761 gacgaggtaa tgcttgatgc tattttattt gctcaccaag aaataaaaaa aatagttgag
     5821 tttatagaag gtatagttgc agaagttgga aaagaaaaaa tgcctgttga attataccat
     5881 gcaggagaag aaataactca attggttcgc gaatttgcaa ctgataagat gaaaaaagca
     5941 gttcagactt ttgaaaagtt agagagaatg gaaaatatgg atagagttaa agaagaaact
     6001 ttagctcact ttgaagaaac tttagaagat tttgaagatt ttgttggaga tatagaagaa
     6061 gtattacaag atataataaa ggaagaagta agaaaactta tagtacatga aaatgtaaga
     6121 ccagataata gaaaacttga agaaataaga cctatatggt gtgaaactgg catgatacct
     6181 agagctcatg gttcagccat atttactaga ggacaaactc aagtacttaa tgttgctact
     6241 ttaggtgctt taggagatgt tcaaaaacta gatgggttag atgaagaaga aaacaagaga
     6301 tatatgcatc attataattt ccctgcatat agtgttggag aagctagacc atcaagagga
     6361 ccaggaagaa gagaaatagg acatggtgct ttagcagaaa gagctttatt accagtaata
     6421 ccatctcaag aagaatttcc ttatgctatc agattagttt ctgaagtatt aagttcaaat
     6481 ggttctacat ctcaagcaag tgtatgtggc tcaacattat ctttacttga tgcaggtgta
     6541 cctataaaag atatggttgc aggtatagca atgggactta taaagcatga tggtaaggtt
     6601 gcagtgcttt cagatataca aggtatggaa gaccatttag gcgatatgga ctttaaagta
     6661 gctggaacag agtatggtat aacagcaata caaatggata taaaaattga tggtatagat
     6721 aaagaaattc tacaacgtgc tttaaaacaa gctaaagagg gtagaatcca tatactagga
     6781 gagatgagaa aaactatatc tcagccaaaa ccagaacttt caccatatgc acctaagatt
     6841 gttaaaatgc aaataaatcc tgacaagata aaagatgtaa taggacctgg tggaaagata
     6901 ataactaaga taatagacga aactggagtt aagatagata ttgaacaaac tggggaagta
     6961 tttatatcag gtattgagat tgatatgatt aagaaagctc aagaacttat aaataatata
     7021 gtagttgaac cagaagtagg aaaaacttat aaaggtaagg taagtagaat aatgaacttt
     7081 ggagcatttg ttgagatact tccaggaaaa gaaggattac ttcatatatc tcatatagct
     7141 catgaaagag ttgccaaagt tgaagatgta ttgaatatag gggatgaagt tgaagttaaa
     7201 gttacagaga ttgatgaaaa aggaagagtt aatttatcaa gaaaagttct tttaccaaaa
     7261 ccagaacata aaaataaata acttattata taattaaaag caaagtctta ggattttgct
     7321 tttttaaata caaaaaagta gataatttta aaatgatagt tatggatggc ttatagttct
     7381 ttttctgtca ggctttactc ttataaagaa gctatttaaa agctgattaa tagagagctt
     7441 tattgatata tatagaatca cttaagttat atttagtgca taaacagagc ttatttttaa
     7501 tagtattaaa taagaaacaa tttgtacata attaggggga gttttaatga taatgatggt
     7561 acttaataag agtaagctca aaaaaatcat aatactaatt ttagtagtgt tattagtatt
     7621 atcaggaggg gtaatggtat taaagttatt taacaacaag ccagtattta atttatttaa
     7681 tggtgtagat ttaccatatg aaagaggtac aaaggataaa agtggatatg ttgcattaac
     7741 ctgtaatata gaccttggat gggaaacaga gtacgtagaa tccattttag aaacacttaa
     7801 aaaagaaaat gtaaagatta catttaatgt aactggaaaa tgggcagaaa agaataagga
     7861 tgaattatta aagataaaaa aacaaggaca tgaaataggt aatcatggat acaaacattt
     7921 agattattct acattatcat atgaagacaa ttatgagcaa atagagacct ctaaaaagat
     7981 aattgaagaa attataggtg aaaaaactaa attttttcaa gcaccagcag gttcttttgg
     8041 tccagaaaca gtaaaggctg ctaaagcatt agggtatact tctatcaaat gggatgccga
     8101 tactatagat tggaaataca aagaccaacc agaggtaatc attgatagaa tgaagaaaaa
     8161 agacattaaa gatagtagta taattttaat gcatccaacc aacgcaacga caaaatgtat
     8221 agatgatatt atagctattg taagagaaaa aggactaaaa ccaggaaaac ttagtgatgt
     8281 atttaagtag acaaagtata aatatttggt taagattgta taagttgtag ttgaattaat
     8341 taaaagactg acttataatg taatacatat aaaaaataaa tataattaaa acatagtgtt
     8401 ttcaataatc caatatgaaa caaagaataa attgttagga gaatgtaatg tataagacaa
     8461 aaatactgga aaatgggctt acaataattg gtgaagaaat accatatcta aagtcaataa
     8521 cattaggtat ttggataaat gcaggctcta ggatagaaga agcacaggtg agtggaactt
     8581 ctcattttat agagcatatg atgtttaaag gaaccaaaaa cagaacatca aaagagattg
     8641 ctagttcaat agataatttg ggtggtcaaa taaatgcatt tacaagtaaa gaatgtacat
     8701 gttattatgt aaaactaata gatgagcata taaatacagg aattgatgta ttgagtgata
     8761 tgatactaaa ttctaaattt gataaaaatg atatagataa ggaaagactt ataatattgg
     8821 aagaacttaa gatgtatgaa gactctccag atgacttatc ttatgattta ttagtggaaa
     8881 atatatatgc taatgatgga ttaggaatga atataattgg gacaaaagaa tctctataca
     8941 atataactag agaatccatg ttagaatact taaataagta ttatattcca aataacgctg
     9001 ttatttctat agctggaaat tttaactttg atgatatggt ggagaaaatc aaatcaaaat
     9061 ttggacactg ggaaaagaaa aatttaagta tagacataag tgaggctaag tttaatcctt
     9121 gctttatatc aaaaaataaa gacactgaac aggtgaactt agctatgtgc ctaaaaggta
     9181 ttccttttga aaatgatgaa gaagtctatt caatggcagt ggtaaataat attttcggtg
     9241 gaagtataag ctcaaggctt tttcagaaaa taagggaaga aaaaggttta gtatattcaa
     9301 tatactcatc acagacatta tataggaaat gtggtgaatt aggtatattt gcaagcatga
     9361 gtacagaaaa tttacaagat gtatataatt taataaagaa agaaattgaa aatataagag
     9421 aaaactatct tacagaaaaa gaaatatctg aaagcaagga acagttaaaa ggaaattata
     9481 tattggattt agaaagtact agcagtagaa tgatgtctac tggtaaatct atgttactta
     9541 gtaaaaaagt aaaaactaca gatgaaatac ttgaatgtat aaataatgtt aatattaatt
     9601 caataaagaa ggttgttgat aaggtattca atatcgaaaa tattggtaca tgtatagttg
     9661 gaagagatgt agaaaagatt ctacacttgg attaatattg aaaaaagtaa atctctggag
     9721 gtataaaata tgaatttatc tgaaatagca ggtaaggaaa tagttaactt ggtcacagga
     9781 gaaagattgg gggtcattgg agaatgtgac cttatactag atgaaactac aggcggtata
     9841 ttagcgcttc taattccaaa agaaaaagga ttttttgcca gaagaaaaga taagtcattt
     9901 ttagaagtac catggagaaa tgtaaaaaaa ataggtaatg acatgataat tatagaatat
     9961 gagggatata tttaggagga aaaaatgagt attttagtgc aaaagtttgg tgggacatca
    10021 gtagaatcat atgaaaaaat gaatgaagta tgtaagatag taaaagcata caaaaaaaat
    10081 gatgaagaat tacaattagt attagtagtt tcagcaatgg gaagaaaagg agctccatat
    10141 gctacagata cacttataaa tttgtgtagt gcagtaaatg atgagccaag taaaagagaa
    10201 cttgatttaa taatgtcttg tggagaaata atatcaggaa caattcttgc taatttattg
    10261 aatgcacagg ggatagattc tgttttcttt actggtcagc aagcaggtat aattacaagt
    10321 gatgaatatt ctaatgcaaa gataaagtat ataaatccta aaaaggtaaa aagagcttta
    10381 gatgatggta aggttgtagt tatagctggg ttccagggtg taacagatga tggagaaata
    10441 actactcttg gaagaggcgg aagcgataca tcagcagttg ctattggtaa agctttagaa
    10501 tgtgaaacag ttgaaattta cactgatgtg gatggtataa tgactgcaga ccctagagta
    10561 gaaccaaacg ctaaagtatt gagttttata gactatgagg aagtattcca aatggctgac
    10621 aaaggtgcaa aagtaataca tccaagagca gtacagttgg ctaaaagtgg aaatataact
    10681 ttagccataa agaatacaat gaatccaact tttgaaggta caaaaatagg ttctttatgt
    10741 agacacttag aagacaatat agaatatgaa caagaaagag attttaaggt tgctgttgca
    10801 aataaagata gcgtagcaca agttaagatt aagtcagcag aagaagtgtt tacagaagta
    10861 ttaaatgaga tagaaaagaa acttataact atagatatga taaatttctt tatatcagaa
    10921 aaagcatttg ttgtagaaga tgctgatata aaatcattaa aggaaatact agataaattt
    10981 gaattagatt atgaagtaaa tagagactgt gctaaggtaa cattgatatg ttcaagaatt
    11041 gctgatgaaa tgtctggtat catgtcaaag gtagttagag gattatcaaa agcaggggta
    11101 tctcttttac aaacatcaga ctcaaatatg actatatctt gtttagttag tgaagaagat
    11161 atgcatacag cagtacatgc tatacatcaa caattttatt taaaataaac tgtataatac
    11221 aattattttt taatcaaatt taagaatttc atatatatct taatatattt gatttatttg
    11281 gtaaaactaa attaaatata attttgatag gagttttttt atgaaagatt atagagaaga
    11341 taatgaaaga tttgataaag ataattgtag tgaagaatct agttgcgaag agagagaatg
    11401 tataaagcaa tttggtacca atgaaatgcc acctcaacct cctaaagata ttcaatgtat
    11461 aactataatt ggagaaattg agggacattt tataggaaat cctcaaaaaa aagctacaaa
    11521 gtacgagcat ataattccaa tgctatactc aattgaggaa agcaatgatg ttaaaggagt
    11581 gttagttgtt ttaaacactg ttggaggaga tattgaagca ggtttagcta ttgcagaact
    11641 tttaaacagt acatctaaaa aagtagttac tcttgttcta ggaggaagtc atagtatagg
    11701 tgttcctctt gctacagcag gagattactc atttatagca ccaacagcaa ccatgattat
    11761 acatccagtg cgaactactg gtcttgtgat tggtataaat gagacttttg agtattttaa
    11821 aaagatgcaa gatagaataa ttcaatttat aataagaaca tcaaatatca aaaaagatgt
    11881 acttgaaaaa cttatgcatg aaaaagatga acttgtaagt gatgttggta gtgtattaat
    11941 aggaaaagaa gctgtggatt atggtcttat agatgaagtt ggaggactaa aagaagcact
    12001 taaaaaatta agagagctta taaaagaatc tgaggaagaa aaaaataatg attaaaattt
    12061 gtttaaataa taaaatttat gatataatga tgtaataaag taggagtgtt agtgttaagg
    12121 cattagcact ttttgctgtg aaggggtaaa acttgctaaa aataaggagt gatattaatg
    12181 gccacgaaaa agaagaaaaa aaagaaggta aataccttaa gttttaatgc agaatatcat
    12241 aatttaataa caatatttat aggtgtattt ttattatata gtttaaattc taattctatg
    12301 ggatggatac ctgtgttaat gcaaaatctt tttaagggac tatttggagg gctttcaata
    12361 gcaataccat ttatagtaat tataacagga cttttaggat tttttgatgg aaatgaatat
    12421 atatataggc taagaaagac taaactatac tacataatta ttttatttat atttgtattt
    12481 tatggattat taaatgcagg aactcttcct gtagatagcc cactaaaagg taacatgttt
    12541 gatgatgtta tgaaattggg tgtaagtgga caaggtagtg gtttgatagc aacaactatt
    12601 gcgtattata tgagtaaaat atttggtata gcaggtggat ggttaataag tatcttcgca
    12661 cttatacttt ctgtaatgtt tatatttaat atttctataa aagatttggt gtcaaatgca
    12721 aaatcaaaat ctaaagcatc taaagacagc aatttaacgt ttaaagataa aattgcaaat
    12781 atgaaaaaat ctgcaataga tatgatgact gatgaagtag atgatactac tataaataaa
    12841 aaaccaggtt tctttaaagg gttaatgtca aaaggtctta ataatgatga tgatgaagat
    12901 gaatattttg aagaagaaaa tagtgatggt gtagatgata aaactataaa aatagttgga
    12961 tttaataagg cagaagatga gtatttagaa atattagaag gaactcaaag tatgccagag
    13021 ttagatgttt taaaagaatt acaaaaagct accaatgaaa atccagttgt agatactaaa
    13081 ccagaaaaaa aagttgatat agctaaacct aatttaaata tagaaaaaac tcaacctatg
    13141 agtattgtag cagagccagt taatgaggat tattcaaact ataaaaagcc tagcattgag
    13201 cttttaaata aagtaaataa gaagtctgat gaaaatggta aaaagaaagt gttgaaaaat
    13261 gcttctcttt tagaaaagac actatcagat tttggagtgg aagcaaaaat taatcaagtt
    13321 acagtcggac ctactataac aagatatgaa atacaaccaa gtccaggagt caaggtaagt
    13381 aaaattgtaa atttaactga tgatatagct ttaagtttag cagctaaaag tataagaatt
    13441 gaagccccaa ttcctggtaa aagtgcaatt ggaatagaag ttccaaatga agaagctcaa
    13501 atggttggtg tgagagaagt tctagaaagt gaagaattta ataattttaa ctctcctctt
    13561 gcaatgggac ttggaaaaga cgtagcagga aaaattataa ttggagatat aggtaagatg
    13621 ccacacttac taatagctgg ttctacaggt tcaggaaaga gtgtttgtgt aaatacatta
    13681 ataagtagta ttttatataa ggcaaatcct gatgaagtaa aattactatt aatagaccca
    13741 aaagtagttg aacttgcaaa ttataatgga ataccacatc tattgatacc agtagttact
    13801 gaccctaaaa aagctgcaaa tgctttaaat tgggcagtta cagagatgaa tagaaggtac
    13861 aaattatttg cagatgctca agtaaaagat gtaacaagtt ataatgagaa agcggaagaa
    13921 aaacttccta aaatagtaat aataatagat gagttagcag atttaatgat ggcaagtgca
    13981 aatgatgtag aagattatat ttgtagatta gctcaaatgg caagagctgc tggaatgcac
    14041 ttgattgtag caactcaaag accatctgtt gacgttataa caggggtaat aaaggctaat
    14101 ataccatcta gaatagcatt tgcagtatca tctcaaactg attcaagaac aatccttgat
    14161 atgggtggtg cagagaagct tctaggtaaa ggtgatatgt tattctatcc acttggtgca
    14221 gcaaaaccag ttagacttca aggggcattc atatcagaga gtgagtcgga aaaagtaatc
    14281 gattttgtaa aaagtcaggt taaagatgga ataaaatatg aagaagatat aattgaaact
    14341 atatctaagg ttaatacttc aaagggtagt gatgaggatg agtttttgag tgaagcgata
    14401 gaatttgtcg tggaaagtgg tcaagcatct gcctctatgc tacagagaag atttaaaata
    14461 ggattcaata gagcagctag acttatagat tctatggaag aaagaggaat aattggagca
    14521 agtgagggaa gtaaaccgag aaaggtatta ataagcaaac aggatttgca gaatttagaa
    14581 ggtgaataga attgtcagtt ataaaaatag aaaaagcact taagctagat aaagtaatat
    14641 ttgtagatgt gagaactgaa ggagaatatg aagaagacca tatattgaat gcaatcaata
    14701 tgcctctttt taaaaataat gaacataatg aagttggaac aatttataag atgcagggaa
    14761 aacatgaagc aatacaaaaa gggtttgact atgtatcgta taaattaaag gatatatatt
    14821 tacaagcagc agaacttgca ttaaattatg ataatattgt catatattgt gcaagaggcg
    14881 gaatgagaag tggcagtata gtaaatttat tatcatcatt aggtgtaaat gtatatcaac
    14941 ttgaaggtgg atataaggct tatagaaatt ttgttttaga gtatttaagg catgtaatgg
    15001 atacaaaaaa ctttgtatct gttcatggat tgactggtac aggaaagact gatttgttac
    15061 atttattaga tgaaaaagga atagacgtac tggatttaga aggcatagct aaaaacagtg
    15121 gttctacctt tggttttata acttttgata aaaagccacc atctcaaaag aactttgaaa
    15181 caaaactatt tgaaagtata tttttttcga aagagaatta tatatttgtc gagagtgaaa
    15241 gcaaacgagt tggaagtgtt acagttccaa atgaaatttt cgaggcaatg acacgagaag
    15301 gacatcatat attattagaa tgtgatattg aaaatagagt tgatagactt tgtagagatt
    15361 atatttatga taaagatgaa ggtaatatat tgattttaaa agaatgtata aacaagttta
    15421 gaaaaagatt gggtaataaa gtagtagatg attatattga tttattagaa tcaggtgaat
    15481 ataaagaact tgtaaaaaga tatcttttag aatactacga cccactttat atgcattcag
    15541 tagagaaata taagtatagt aagattataa attttaatga tacacaaaaa gctttagaag
    15601 atgttataga cttatatgag agtatattgg aaggagaaag tgaatgttaa aaatagcatt
    15661 ggaatcatta ggatgctcaa aaaatttagt agatgcagaa ataatgatgg gaattttaaa
    15721 taacaaaggc tataaattaa ttggagattt tgaagaagct gatgtaatta tagtaaatac
    15781 atgtgggttt atagagtcag ctaaacaaga atctatagat acgataataa actttgcaga
    15841 gttaaaaaaa actggcaatt taaagttgtt gatagtaaca gggtgtctag cccaaagata
    15901 ttctgaagaa ttaaaaactg aaattcctga aatagatgct atagtaggaa caggaagcta
    15961 tcaaaatata gataaaatac ttaaagaatt aagtgaaatg catcaaattg taagccttaa
    16021 tgatatagag tttgtattta atgaagattt accaagatat atatctacac ctagctatat
    16081 ggcctattta aaaattggag aaggatgctc caataattgt acttattgta taataccaaa
    16141 actaagaggt aaatatagaa gtagaaaatt tgaagatata attaaagaag ctaagaaatt
    16201 agctgaatct ggagtaaaag aacttgtggt tatagcacag gatacgacaa agtatggttt
    16261 tgatttatat ggaaaagaaa gattatcaga acttttagaa gaacttgcaa aaatagatgg
    16321 atttaagtgg ataagggtta tgtattcata tccagaatct ataacagaag aattgataca
    16381 agttataaag aaatatgata atatatgtag ttactttgat atgccaatac agcatgcaag
    16441 taacaatatt ttaaaattaa tgaatagaaa aactactaaa gaagatatat taaataaaat
    16501 caatctgata agaagtaata taccagatgc tatacttaga actacaataa tagtagggtt
    16561 tcctggtgaa acagaagatg acttcaaaca acttgtggac tttgttgaag aggttaaatt
    16621 tgatagactt ggtgcatttg catattcaag agaagaagat acaccagcag atagattacc
    16681 aaaccatata gatgaagaag taaaaataca aagaagagat actttaatga tgattcaaca
    16741 aaaaatatct gaagaactta atgacaaaaa gataggaaaa acttatgagg tgttaataga
    16801 agaacagata gaagataatg tatatacagg aagaacacaa ggtgatgcag aagaaattga
    16861 cagtatagtg tatgtaaaaa gtgtagacaa tcttgaagta ggagaatttg taagtgttca
    16921 aataaatgat gcaatggaat acgatttaat gggagatgtt ttatatgaac ttgcctaaca
    16981 agttaacttt gtttagaata tttttaatac cagtatttgt tttaattatg ttgctcaatg
    17041 taccaaataa atttttaata gcttgtatta tttttataat agcttcaatt actgatgctt
    17101 tagatggaaa aatagctaga aaatacaatc tagtcactga ctttggaaaa tttatggacc
    17161 cattagcaga taagttattg gttatttcag cacttacatg tatgatagaa gaccatcttg
    17221 taagtagttg gatggtaatt ataatagtgg ctagagagct tacagttagc atattaagag
    17281 ctatagctgc tgctgatgga aaagtaattg ctgctggaaa cagtggaaaa cttaaaacga
    17341 taactcaaat ggtatctata gtgtttttat tgttaggtgc tcagtttgaa aatgtattga
    17401 tattaaatat tggtgaaatt ctcattctta tagctacact acttacatta tattctggat
    17461 gggaatatct atataaaaat aaagagcttt ttatgtcttc taagtaaaaa attatgcttt
    17521 aataaataaa aactaatgat taataaataa aaaataacaa cttaaaattt taaaaatgta
    17581 aaaaagggta tactattata gtatacctct tttcatttta agaatatttt cttttgtgta
    17641 tataattatt aataatggtt tataaataaa atgtaatgaa taaaaatata atcattagta
    17701 gcgtttttaa attgactagg tttgatttat gttatataat taatatataa caagagaaca
    17761 aatgtttgta gataaatgaa gggatggtat agagatgagt gtagatcaag aaaaattaaa
    17821 agcgttgaat gaagctttag gtaaaattga aaaagatttt ggtaaaggtt cagtaatgaa
    17881 attgggagaa gcaacatcta tgtctataga tgttatatca acaggagcga ttggtttaga
    17941 catagctatt ggtataggag gtctacctag agggagaata gttgaagtat atggtccaga
    18001 atcttctggt aagactactg ttgcgcttag ttgtgtagca tcagctcaaa aagatggagg
    18061 aatagctgca tttatagatg cagaacatgc acttgaccca gtatatgcaa aagctttggg
    18121 tgtggatgtt gataacctaa taatatctca accagataca ggtgaacagg ctttagagat
    18181 agcagaggca ttgataagaa gtggagcgat agatataata gtaatagact cagtagcagc
    18241 attagttcca aaggctgaaa tagatggaga tatgggtgat tctcatgtag gtttacaagc
    18301 tagacttatg tcacaagcac ttagaaagtt aactggttca attaaaaaat caaattgtgt
    18361 tgctatattt ataaaccagt taagagagaa agtaggaata atgtttggaa acccagaaac
    18421 tactactgga ggacgtgcac taaaattcta ttcatcagtt agattggatg ttagaaaaat
    18481 agatacaata aaacaaggtg ataaagttat aggtagtaga actagagtta aagttgttaa
    18541 aaacaaagta gcaccaccat ttaagcaagc tgaatttgat ataatgtatg gagaagggat
    18601 ttcaaaaatt ggagaccttt tagatatagc tgctgatgta gatatagtta aaaaatcagg
    18661 ttcatggtat agttacaatg atactaaact tggacaagga agagaaaatg ttaaaaaatt
    18721 cttggaagat aatttagatt taactactga aatagatgag aaagttagag cattttacaa
    18781 tttaaatgaa gaacatgaag aatcaggtac ttcagtatca aaagaaattg tagaagaata
    18841 agtaaaaata caaaaaaata actagtaatt aaagacatgc cacgctccct attagcttga
    18901 cacaatgttg aaaaaattat aaaattaagt gaggataaaa tatctaaatt taattttaat
    18961 tattaggaat attttttaat catagtgatg acattttggg attattaacg aaggaggtgg
    19021 atttcataga tagtgtagta atgattgtaa taggtgcagc tgttggtatt atagctggat
    19081 attttgttag aaaaaatata tctgaagcaa aaattggaca agctgaaaac ttggccaaag
    19141 aaataataga taaagcacac cacgactcag aaacagtaca aaaagaaaaa ttactagaag
    19201 ctaaagaaga gatccataag tggagaacag aagctgaaag agaaaacaga gaaagaagaa
    19261 cagaagtaca aaagtatgaa aaaagagtag tacaaaaaga agaagtctta gatagaaaat
    19321 tacaaaattt agaatctaaa gaagtaaacc taagtgaaaa attaaaggta gtggaaaaga
    19381 aagaagaaga agttgaagta ataaaaactc aacagttaga aaaattagaa agtatatcag
    19441 gaattacttc tgataaggcc aaagaaatca tcttaaccaa tgcggagaga gatgtaagac
    19501 gtgaaatgtc tataatgata aaagagatag aaagtcaagc taaagaagaa gctgataaga
    19561 aatcaagaga aattatagga tatgcaattc aaaaatgtgc agcagatcac gtagccgaaa
    19621 ctactgtaac agtagtaagc ttgcctaatg atgaaatgaa aggtagaata ataggtaggg
    19681 aaggtagaaa tataaggact ttagaaacct taacaggtat agaccttata atagatgaca
    19741 ctccagaagc cgtaatttta tcaggatttg atccaataag aagagaaatt gcaagaattg
    19801 ctctagaaaa attaatagca gatggaagaa tacatccagc tagaattgaa gaaatggttg
    19861 aaaaggcgag aaaagaagtt gacaatatta taaaagaata tggtgaacaa gctgcatttg
    19921 aaactagtgt acatgggatt catccggaat taataagatt attaggtaga cttaactata
    19981 gaactagtta tggacaaaat gtacttaaac attctataga agttgctcat atagctggta
    20041 taatggctgc tgaaatagga gcagatatta gattggctaa gagggcaggt ttattacatg
    20101 atataggtaa ggctgtagac catgaaatgg aaggtacaca tgttgaaata ggtatggatt
    20161 tacttagacg ttataaagag tctaaagaag ttatacatgc catgagtact catcatggag
    20221 attacgagcc tcaaacagta gaggctgtat tagttacagc agcagatgca atatcagctg
    20281 ctagacctgg tgcgagaaga gaaactttag aagcatatat aaagagactt gaaaaattag
    20341 aagaaatagc taattcatat gaaggtgtag aaaaatcatt tgctatacaa gctggtagag
    20401 aaataagaat aatggtaaaa ccagaagcta taaatgatga agaaatacat ctattggcta
    20461 gagatatgac taagaaaata gaggatgaac ttgaatatcc tggacaaata aaagtgagca
    20521 taataagaga aacaagagct atagaatatg caaagtaaaa gaaataatat ctaaataata
    20581 agaaaatatt tttagaaatt taaatttgcc acaagatatg ataatatatc ttgtggcttt
    20641 taaattgttt aagtttaatt ttatataatg caaaaataat ctaagtgcta aaagtgctac
    20701 ttacaaaaga ttaataaaat aaagatttat atatggatta tttatataat tatccaagtt
    20761 tgtttgatat aatgaagttg taaaatcaat actttactac aaaataaata gtaaatacta
    20821 cagtaaaa
//
LOCUS       DAMJXI010000064        19236 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.066, whole genome shotgun sequence.
ACCESSION   DAMJXI010000064 DAMJXI010000000
VERSION     DAMJXI010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19236
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.066"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            198..776
                     /locus_tag="PC465_002942"
     CDS             198..776
                     /locus_tag="PC465_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2650226.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            815..1393
                     /locus_tag="PC465_002943"
     CDS             815..1393
                     /locus_tag="PC465_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2650227.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            1479..2108
                     /locus_tag="PC465_002944"
     CDS             1479..2108
                     /locus_tag="PC465_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2650228.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            2098..4857
                     /locus_tag="PC465_002945"
     CDS             2098..4857
                     /locus_tag="PC465_002945"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HDF2650229.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGRDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     PKKTA"
     gene            4944..6506
                     /locus_tag="PC465_002946"
     CDS             4944..6506
                     /locus_tag="PC465_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HDF2650230.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAMDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGAIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDVHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            6507..7643
                     /locus_tag="PC465_002947"
     CDS             6507..7643
                     /locus_tag="PC465_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HDF2650231.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            7707..8783
                     /locus_tag="PC465_002948"
     CDS             7707..8783
                     /locus_tag="PC465_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HDF2650232.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNSHFITGILIPKANSELIENCIEALDSMNLQDMYVI
                     PIVETKEFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFADALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            8761..9999
                     /locus_tag="PC465_002949"
     CDS             8761..9999
                     /locus_tag="PC465_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HDF2650233.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGIRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELDCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMASKESLKNEKEKILFLGTEEFMYIPMLFAKEKENKYDIYYHST
                     TRSPIINIDKNNYPIKSKFMLKSFYNIDIQNYIYNIDKHNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            10053..11141
                     /locus_tag="PC465_002950"
     CDS             10053..11141
                     /locus_tag="PC465_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HDF2650234.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYIRSKYNISLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNVKFKKYFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLIGKNDFHGAKFYRHLKDKDESMNYIKTIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFIL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDI"
     gene            11169..11960
                     /locus_tag="PC465_002951"
     CDS             11169..11960
                     /locus_tag="PC465_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HDF2650235.1"
                     /translation="MIVFSDLDRSIIYSNKFLNADSKYTNIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKSDYEPIESMIHKFKDYLNVDGITNFKVAEDTFFYIVVDLSRFNLDSIKEYTNI
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAVGDSIMDYGMLNISNK
                     SYVLKHGDINKNEIENSFISSSFNGMSGTEEILSNILDENCLLNI"
     gene            complement(12075..12629)
                     /locus_tag="PC465_002952"
     CDS             complement(12075..12629)
                     /locus_tag="PC465_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDF2650236.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIVVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTQKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDEVCISVWAMTPPSF"
     gene            12825..14027
                     /locus_tag="PC465_002953"
     CDS             12825..14027
                     /locus_tag="PC465_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HDF2650237.1"
                     /translation="MKSFVSPDNIWVLWAVVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGITEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            14103..15083
                     /locus_tag="PC465_002954"
     CDS             14103..15083
                     /locus_tag="PC465_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HDF2650238.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISENKINILIGLE
                     GLSHIGRNIDLLDYFYKEVGARHASLTWNEQNELATGCLGDENRGLTEIGKKAVNKME
                     KLGMIVDVSHLNEKSFWDLMSVASKPVIASHSNARSLCDAKRNLTDNQLKEISNTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NASVPSVDGLESTHTAQNIVVELENRGYKKKDIELISSGNFYRLFKYILK"
     gene            15331..16284
                     /locus_tag="PC465_002955"
     CDS             15331..16284
                     /locus_tag="PC465_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDF2650239.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RIPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFTFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRANIWYTGLLGAIFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            16274..17230
                     /locus_tag="PC465_002956"
     CDS             16274..17230
                     /locus_tag="PC465_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDF2650240.1"
                     /translation="MKLSLNQKIYFVSILLFISIALFIIYGIDMNHLEYALSQRIPKI
                     FAMVLGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAMMIGASLLLYKMLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKAVKKMIILIAILVSISTALIGPMTFLGLLLANITREIFKTYKHTYLISGSMLIGM
                     ITLIIGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            17227..17982
                     /locus_tag="PC465_002957"
     CDS             17227..17982
                     /locus_tag="PC465_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2650241.1"
                     /translation="MIEIKNIFKRYKNKNVVDDVSFSIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRSLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVEKVG
                     RTDEIVNEKVLEDIYEMNFNIKNINGNRICIYF"
     gene            18074..19039
                     /locus_tag="PC465_002958"
     CDS             18074..19039
                     /locus_tag="PC465_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2650242.1"
                     /translation="MNKKAAIVAAVAIIGLVTVFALGGSKKNESKTSENSNNTIKITH
                     NLGETDVKLNPKKVVVFDYSALDTMDALGVAENLVGLPKASLPASLEKYKDDKYADLG
                     GLKEPDLEGIKSANPDLIIINGRQEDFYEQLSKIAPTISTSKDDKKYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFENKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDVKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
BASE COUNT         7638 a         1948 c         3414 g         6236 t
ORIGIN      
        1 atagctttta tacatttaat aaagtatgta aaatctatgt aaaaagtaag aaatataaac
       61 atttttttaa ttatatttta aaaatatcaa gcaagttttc ttcacaaatg aataaaaaat
      121 gttataatat gattaaagaa aaagataaat aattagcaag atttgtttag ctaaaattaa
      181 caagggagcg ataaattatg ggtataacat tatcaaaagg ccaaaaggtt gatttaacta
      241 aaggaaatcc aggtcttaaa aatattttag taggtttagg atgggatact aacaagtatg
      301 atggtggatt tgactttgat ttagatacag cagcattttt aacaggagca agtggaagtg
      361 ttactaatga tggagatttt gtattttaca acaatttaaa acatacatct ggagcagttg
      421 agcatctagg agataacaga actggcgaag gtgatggaga tgatgaacaa atagttgttg
      481 atttatctaa gattcctgga gaaataagca agatttcttt tactgttaca attcatgatg
      541 caacagaaag aagacaaaat tttggacaag taagtaattc ttatataaga atagtagata
      601 aagacacaaa tgaagagtta ataaagtatg aattaggaga agattttagt atagaaacag
      661 ctatagtagt agctgaaata tataagcaca atggagaatg gaagtttaat gcactaggtt
      721 ctggctttga aggtggtctt gctgcattat gtggaaactt tggaataaac ttataatttc
      781 aactataaca ataaactaaa gggggatatt ttccatggct atagtattaa aaaaaggaca
      841 aaaaatcgat ttaactaagg gaaatccagg tcttaaaaat ataaaacttg gactaggatg
      901 ggatacaaat tcatttgata gtggctatga ttatgattta gatgtaagtg ttttcatggt
      961 tggagaatct caaagagttg aaaaagatga agattttata ttctacaata acttaaaaca
     1021 tccatctgga gcagttgaac acttaggtga taatagaact ggtgaaggtg atggagatga
     1081 tgaggaaata ttagtgaatt tagagacaat gccaaagcat atacaaaaga tagctgtaac
     1141 agttacaata tatgaggctg ctgaaagaag acaaaatttt ggacaagtaa gcaactcata
     1201 tataagagta ttaaattctg aaaatgatga agaaatatta agatatgact taggtgaaga
     1261 atttagtata gaaactgcaa ttacagtatg tgagatatat aagtataatg gagaatggaa
     1321 gtttagtgca gttggagcag gatttgaagg tggcttagaa gcactttgta gaaactatgg
     1381 cttaaatgtt taatttaagc aatataatat attaaatata aataacctat acaaataatg
     1441 tataggttat attatataaa attttgtgga ggtttagtat gtcgattaat ttatcaaaag
     1501 gtgataaaat agatttaaaa aaatctaacc caggactgag taacatactt gtaggtctag
     1561 gatgggaccc tgtgcaacaa tctggaggag gtttttttaa atcgttattt ggtggaggac
     1621 aagctgatat agattgtgat gcatctgtat ttatgcttaa tcaagaaggt aaattaagtg
     1681 gaataaaaga tttaatttat tttggaaatc taaaaagtgc ctgtaaatca gttttgcata
     1741 caggagacaa tctaactggt gagggtacag gtgatgatga acaaatccta gttaatttgg
     1801 ataaagttcc atcaaatatt cataaattat tgtttgtagt aaatatatac aattgtgtag
     1861 atagaaaaca acactttgga atgatagaaa atgcctatat aagagttgaa gaccaaggta
     1921 ataagaaaga gatagcaaaa tacaatctat ctgataatta ttctgaaaaa actactctta
     1981 tagtaggagc tatatataga aaagatggaa gttggcaatt taaagcaatt ggtgaaggaa
     2041 caaaagatgc gggtcttaaa gaagtaatgc aaaatttaga caggattgag tgtgcatatg
     2101 gaatttaata atgatatcaa atattataat gtagataaag aagaagttac aaaagactta
     2161 tctgttaatc ctgaaaaagg tttatcagaa tcagaagtca agactagaag agaaaaatat
     2221 ggtttgaatg aatttactcc aaaagaagag ggtagttttt gggatgattt aaaggaaagt
     2281 ttaagtgaac caatgatagt tatcttgatt attgcagcag tagtaagtgc agtaattggg
     2341 gaaactcatg atgcaatagg gattgtaggt gctatagcaa taggtatagc aataggtatg
     2401 attacagaag gtcgttctaa gaaagcagca gaggctcttt ctaagttgac tgaaaacata
     2461 gaagtaaaag tattgagaga tggggaagta catcaaattt ctaagagtga attggtacca
     2521 ggtgatatag tatatattga aactggtgac atggtacctg ctgatggtag acttatagaa
     2581 agtataaacc ttaaaattag agaagatatg ttaacaggag aatctgatga cgtatctaaa
     2641 aagtgtgatg tagtagtttc tatggaagag atagaatcta aaggagcagt agtagtacag
     2701 gagccaatac ctgcaaaaca gataaatatg gtgtttggtg gtacacttgt agcttatggt
     2761 agaggagctc tagttgtaac ttcaattgga gataatagtg aaatgggtaa aattgctcaa
     2821 aacttatcag aaacagatga gcaaactcca cttcagataa aacttggaaa tttaggtggt
     2881 ttgatagcca aagtttctag tgcagtagca ggattactat ttatatttat ggttttccaa
     2941 atgataagta agaatgtatt aaatgtagat atgtctggaa tattaccgtt tttagaatca
     3001 atagacccag ttaaaacagc atttacagta tgtgttgcgt tgatagttgc agcagtgcca
     3061 gaaggtcttc caactatgat aaatatgaca cttgcaataa caatgcaaaa aatggctaaa
     3121 ataaatgcat tagttaccaa aaaagaagct tgtgaaacga taggttctgt ttctgtaata
     3181 tgttcagata aaactggtac attaactgaa aatagaatga ctgtagaagt tgcatatgtt
     3241 gatggcagat atattgaaag ttcagaagag gaaataaata gttattttga agaaaactgt
     3301 atgataaact ctacagctga tgtagagcac aatgatggtg atattaagta tttaggaagt
     3361 gctactgaat gtgcattgct tttatattac aaaaacgtag attatagaca agttagaaaa
     3421 aattctaata tagtagctca aaatcctttt acttcagatt caaagagaat gacttctgtt
     3481 ataggtcgag ataatcatca tgtgctatta tcaaaaggag caccagaagt attacttgaa
     3541 ttatgttcac atattcaaag aggaaaagac atagttccat taactgaaaa tataaaacat
     3601 gagattttag aagaaataaa gaaattgcaa ataaaatcaa tgagaacttt agggtttgca
     3661 tataaagaaa tctcacaagc tgaagaagaa gcagcagtaa ctgctgaaag tgatgctatg
     3721 aatgtaagtg caatggaaaa caatttagta tttagtggtt ttgttggtat aagagaccca
     3781 cttagaaaag atgttataga gtctgtaaat acagcaaata aagctggtgt ttctgtaaaa
     3841 atgcttacag gagataatat aaatacagca agagctatag gtgaagagtt aggcctatta
     3901 aaaaataata tgagagtggt tgaagcttca tatatagata ctttagatga tgaagaatta
     3961 aaacaagaga tacaaagtat ttcaatcgtg gcaagaagta aaccagatag taaaatgaga
     4021 atagtttcag ctctgcaaaa gagcggagat gttgttgcag taacaggtga tggtataaat
     4081 gatgctccag cactttcaaa agcagatgtt ggtatagcaa tgggtatatc tggtacagag
     4141 gtatctaaaa acgcagcaga cataatttta actgatgata gttttagtac cattgtaaaa
     4201 ggtattaaat ggggtagagg aatttatgat aacttccaaa gattcgttca attccaatta
     4261 actgtaaatg taattgcatt tttagtggct ataatatctc aagttatggg acaagagatg
     4321 ccatttacta caatacaatt attatgggta aacatcatta tggatggacc accagcacta
     4381 gcattaggtt tagagccagt tagggaccat gtgttaaaca gaaaacctgt tgatagaaaa
     4441 gccaatataa tttctaagtc aatggtgtat acaatagtat taaatgcatt ttatataaca
     4501 gcaatactaa tgttacaatc tacatttaat ttcttaggag ttgatgaagc gcataaggga
     4561 acagtaatgt ttgcgttatt tgcttttagt gcactgttta atgcatttaa ctgtagagag
     4621 tttaatgcag atagtatctt ccctaatttt acacataaca aattagcact acaaataata
     4681 gtgttgacag gaattgcaca agtaatattt actcagctat tccaagattt ctttaactct
     4741 gtagcaatgg attttatgac atgggtaaaa gttttatgtg tagcagcaag tgtaattgtg
     4801 gttaatgaag ttgtaaaatg tataataaga ctggtaaaac caaaaaagac tgcttaaaac
     4861 aaatttttta gaagaaaaca gactgactca aaatatgaat tttgggtcag ttctgaataa
     4921 acatttaaat tgggaggata gttatgggtg actcaaaggt atttgaaaaa atattctcca
     4981 gccaatcaga tagaggaaat tacactcctt caaagggata tctaagttat tttatttcgt
     5041 atattggttt agaagatgaa gttttgtaca atctcgagat atttaaaaca aaacaaaata
     5101 ttgatagcaa aaaagatatt gctttattta ctgatgttat agcaaatcct agtgattttg
     5161 atattataaa ttattttaaa agtggacttc aaaaatatag aactagcatg gaagatgtag
     5221 atataaatat tttgggattt gaagagattg attataaaat aaagcaagca atggatagag
     5281 tgttaaaaga agaggaaaaa gaatttacta atgatagagt taaacaaaat tttatagtga
     5341 aaataatggc atggataaaa atttatatcg gtgctttaga tataaataaa aatgaagctc
     5401 caaaagtaat attttatgga gatataaaaa aacatgaagt ttatttactc ttaatattat
     5461 acttggcagg ttttgatgtt ttatatctta atccaaattc aaagagtaat atagatattt
     5521 taaaatcaga aagatacaat atagagtttg aagaagccaa cataatagaa gaaaaaattt
     5581 cttttgaaga aagggttatt ttaggggaaa aaatagataa aagttctgta aaaaaagctt
     5641 ttactgttgg ggcagaagca tcaaagcgta taagtgagga attgttaaat gatgcaggat
     5701 ttataaaacc ttggcaactc caagatagaa aaataaaaaa tctacttcta agttcaactg
     5761 ttgatgaaat atcaatatac tggaatcaac cacttaaatt aagaccagga tttaagttta
     5821 atgatgctat tgtagaagct ccaaattttc tttctaagat taatggaata tataacgata
     5881 agaatgaata tattaagttt ttagatttat taagagattc ggaaagttca acatttattg
     5941 aatttaatgg agatgtagat agattttcaa aagcttttac aagagaagct tttagtttat
     6001 cctttttatt ggattcaaaa ggtgcaatag ataaaaactc tgttttaaat aataaagatt
     6061 attccatatc aacactagca ttgaatcaac aaattatgat tttagagaaa gtggaagagt
     6121 tgttagaagg aagtatgttt ttgaatggtt taagtggaga agacaagata aaaggtctat
     6181 ttacagtact tcacatggat aagaaatttg ttcatatgat gaacaatttc gattactcac
     6241 ttataaaccc aaaattgatt atatacatgt acaagagtat tgtatttgat aaagaaatag
     6301 tttttcttat gcttttactt agtaagattg gatttgatat tatcatatta tgtccaggag
     6361 gagaaaacaa tatagagaat gttataaata accaattgat tgatgtacac agattggata
     6421 aaatggtata tgaccttaaa ttaaattcgc ttgaaaatga tataccttta cttaaaaaaa
     6481 tttttggaaa gaggagacga ttttagatgg ggataaatat aaatagtttt tcaaaagata
     6541 agaactctgt agaggttact gagaatttgc ctacagcagt tcaagaagaa aacttcgata
     6601 taatggaata tacaaataat aaaaaaaatg aactgagaaa gtctaaggaa gttgaggcat
     6661 tgacatctct tatagaagta gaaaatccag atacgatttt acagtttggt aggaaagcat
     6721 ctgaaggagt agcaagagtt tctgatagcc ttttaaatac aataaaatta aatagaaatg
     6781 aagaaaattc taaaatgctg gttcatttaa ctaaaataat ggataagttt gatttagacg
     6841 attttcaaga aactaaggaa ccaaatttcg ttcaaaaact tttcaaaaaa gctaataatg
     6901 ccattgaaat gatgtttcaa aagtatgaaa cattgggagg agaagttgag aaaattcaaa
     6961 ttgagcttga gcaatacgaa agagatatag cactttctaa taagcaaata ggtgctatgt
     7021 taaatgaaaa ctttgagttt tataatgaac ttcaaaaata tattgttgct ggagaaatgg
     7081 caatagaaga aatggataat gaaatactac ctttctttaa acaaaaatca gagactagtg
     7141 gagatcaaat ggatgttgtc aattatcaag aactattaaa agtttatgat atgttaaatc
     7201 aaagagtcta tgatttaagg atagcagaaa atatagctat ccaaacaata cctatgctta
     7261 gaggtatgca acataataat tatggtttaa ttagaaaaat aaatagtgca tttgtcgtaa
     7321 ctttaccagt atttaaacaa tgtttatctc aagctatatt acttaaaaag caagaattac
     7381 aagcaaaatc tctaaaagca cttgatgaca aaactaatga attattgctt agaaatgcac
     7441 aaaatgtaag tactcaaagt gcacaaatag ctagaatggc tggaacaagt tctgttcaaa
     7501 tagaaacatt ggaaaaaatg tacaatacta tcaaatctgg tatagatgaa actatgagaa
     7561 tagaagaaaa caatagagct ttaattaagg ataatacaaa gagattggaa gaattaaata
     7621 cgactataat ttataataag tagtattata ttaagggcta atttgtataa agttggccct
     7681 ttctatgtat atgaggaggc tagacattga aatatttcga ttatatctgc aaagatgatt
     7741 tagagagaat ttttttgaag gagccagaag attttagtgc taagactgaa aaagatgtgt
     7801 tgaaatatgc actgggcgct tttttatacg ttccagctac tcaatataat atgatttata
     7861 agagtattat aggggatgtt aagggagtta gaccattagc tatttgttta gaagatgctg
     7921 ttggagtaaa tggagagtta gaggctatag agaatcttag attaatttta aaaaatatta
     7981 gcaatgaaag tataactaat aaagatggaa taccactaat ttttgtaaga ataaaagatg
     8041 tggagcaact gttgagaatt aaagagatta taattaaaaa tagtcatttt ataacaggaa
     8101 tattaattcc taaagcaaat tcggagttaa ttgaaaattg tatagaagct ttagattcta
     8161 tgaatcttca agatatgtat gttattccga tagtagagac aaaagaattt atatataatg
     8221 aaaaaaaaga acttagtttt actaatttgt acaatgctat tttaagacat aagtcaagaa
     8281 tattaagcat tagagtaggc ataactgata tattagggat gtatggtata aggagagata
     8341 aaaacttctc tatatataat aatttgattt gttcttcatt tatattagat ataatcacat
     8401 atcttcaaag accagagtta gatataccta taagtggtgg agtatcagaa ttttttgata
     8461 tgacgaataa ggatataaga aataagtata tagaagaaat attattggat aaatatcatg
     8521 gattaattgg aaagaccgta attcatccaa tgcaaattca aattgtacaa gcgctatcta
     8581 cagtatcata tgaagatttt gctgatgctt tggatatact ggatagtaca gacagtaagt
     8641 atggtgtgag caagggtgta ttaggagaga gaatgaatga aacaaatcca cattttttat
     8701 gggctaaaaa aacattgatt ctatctaaaa tatatggtgt attaaataaa ggagtagact
     8761 atgaagaatt gcttaaattt taattgtgag attgacatta ttgataatcc attgaattta
     8821 gaactaaatg attttttaga cgtaggaata agaaataata gcaaaagacg ttttttgttt
     8881 atctcaaaga aactcggtaa acatttagca tgtaagccaa gtgagatgga taatttggga
     8941 aaattaatgg ctacaattta taatgaaaaa aataaggaag aatcaaatgg tactgttata
     9001 gcttttgctg aaactggtac agctgttggg catagttttt ttgattactt atgtggagat
     9061 tatgaattta ttcatactac tagagagcag tttgacgagt tagaaaatct ggaattttta
     9121 gaggaacatt cccatgcaac agaccagaat ttatactttg gtatgcttaa caactttaaa
     9181 tttggagatg agataatatt ggttgatgat gagattacca cagccaatac atgcatgaat
     9241 ataattagga aaattcaaag catttatcct aaaaagaaat acactatatg ctcaatactc
     9301 aattgggtaa gtgatgaaaa tttaagtaaa gttactcgtt tagaaagaga gctagattgt
     9361 aagatagatt ttgtatactt atttaaagga aactttaaat tttatataga tgaagatatt
     9421 atttcaaatt acaacgataa ttatagtatt actaaattag agactatttc aagtgataaa
     9481 gtaaatttag tagtaaatca tatttatgtt gatttagaag attatattgg aaataagaaa
     9541 tatgtaaaat atacaggaag atttggaatt aatagaagag aacaatttag attaaaagaa
     9601 atcgttaaga gagaaagtaa aaaaataact atggccagta aagaatcttt aaaaaatgaa
     9661 aaagaaaaga ttctattttt aggtactgaa gaatttatgt atatacctat gctgtttgca
     9721 aaagaaaaag aaaataaata tgatatatac tatcattcaa caacaagaag tccaattatt
     9781 aatattgata agaataatta tcctattaaa agtaaattta tgctaaagag tttttataat
     9841 atagatattc aaaattatat ttacaatata gataaacata atttttctaa gtgttattta
     9901 tttgtagagc tgaataaaag tgaaaattct tatctagaat ttattgatat aattaaaaaa
     9961 acaagtataa aagaattaac tatagtatgt tgtagctaaa gtgttttaac aggataaaat
    10021 atatcacgat tttaagatag gagttgagtc atatgagaga ttttagcacg tattctaaag
    10081 atgatgttat ttttttatta aaagatatat caaatttaat tgaagaagaa ggaaataaag
    10141 aaagagaatt aaaaatacaa aatggtagac attattcaga aatgatacca atagagtatg
    10201 aagttagtga agattatctg aatttatatc atgagaaact aagagaaaat aaagataaac
    10261 ttgcattttc tataggagtt atgtgtgaaa aaataattaa aaaaaatgga aatgatgtag
    10321 tactagtttc acttgctaga gcaggaacac ctattggtat tttggcaaaa agatatataa
    10381 gaagcaagta taatataagt ttacctcact atacaatctc tataataaga gataagggaa
    10441 tagatatgaa tgcaattgaa tatatagtaa agaatcatcc gagctcaaaa attcaatttt
    10501 tagatggatg gactggtaag ggaactatat caaaagaact tgaaaaagca tgtgatgaac
    10561 ttaatgttaa atttaaaaaa tattttgact caacacttgc tgtattagct gaccctgctg
    10621 gatattcagg actttatgga attagagaag atttcttaat accaagtgca tgtttaaatt
    10681 caaccgtttc tggtttagta agtagaactg tactaagaga ggatttaatt ggtaaaaatg
    10741 actttcatgg agctaagttt tatagacatt taaaagataa agatgaatct atgaactata
    10801 tcaaaactat agaagaatgt tttaaaaatc aatttaagaa tatatctgat gaagttgaaa
    10861 actgggaaag tgacattata acaagagatg gatactttga tgttttaaat ataaaagaaa
    10921 agtataacat aacagatatt aactttatca aaccaggtgt aggggaaacg acaagggttt
    10981 tacttagaag agttccgtat aagattcttg ttaaagactt aaatgataaa tctttagacc
    11041 atatattcat attagctaag gagaaaaatg ttgaagttga acaaatggat ttaaaagcct
    11101 ataaatgttg tggaataata aaaaatatga aagatattta ggaaatatat tagacaggag
    11161 aatattgaat gattgttttt tcagatttag acaggagtat catttactcc aataaatttt
    11221 taaatgctga tagtaaatat actaatatag aaatttatag ggaaaaagaa atatcttata
    11281 tatctttaga tactataaat ttaataaagc aaatacaata ttatggtatg tttataccta
    11341 caactactag aacagtggag caatttaagc gtatagaatt taataaatat gggatttatt
    11401 ttccttggag tataacttca aatggaggag ttatacttaa agataatgaa atattgaaat
    11461 catggagtga aaaaatagat aaactaaaat ctgattatga gcccattgaa agtatgattc
    11521 ataaatttaa agactatttg aatgtagatg gaataactaa ttttaaagtt gcagaagata
    11581 cattttttta tatagttgtt gatttatcaa gatttaattt ggattcaatc aaagaatata
    11641 caaatatatt ggaatcaaaa aattggaagt tttatgtgag tggcagaaaa atatatttta
    11701 taccaaaaga aatttcaaaa gaaaatgcta taaaatactt gactaaagaa ttaggaatag
    11761 aatattttta tgcagttgga gattctatta tggactatgg tatgcttaat atctcaaata
    11821 aatcctatgt attgaagcat ggtgatataa ataaaaatga aatagaaaat tcatttatat
    11881 caagttcttt caatggaatg agtggaactg aagagatact atctaacatt ttagacgaga
    11941 actgcctact taacatataa tgactgatat ataaataata aactagaaaa atctgaaata
    12001 aattatagta aagtttatca tactaattta tttcagattt ttatcaattt atatttaagt
    12061 aagaactcaa tatgttaaaa tgaaggtgga gtcattgccc agactgagat acatacctca
    12121 tcatcataat tttcatacac atgtggtata gtactgttaa aataaaaact atctccttcc
    12181 tccaatagat attccttatt tccaagtgtt atcttcattt taccttttat tatatagcca
    12241 cattcttctc cttcgtgtgt cacaaattca ctgttttttt gtgtatgacc atctagcgta
    12301 acaagtataa attctatttt tttcccagat aaattaggaa caagaagttc ataaaatttt
    12361 gtagaatcat tagttactat tttttttcga ttatttttct ttactactat atcagagtct
    12421 tctcttccaa tctcttcaaa aaaataacct atatttatat caagagcttt tgatattttc
    12481 cacattgcta caatagatgg aacaaccata ttacgctcaa tttgacttat taagcctgta
    12541 cttaaatctg aattttttgc taaagtagag atacttatat ttttagattt tctaagagat
    12601 ctaattttgc ttccaacatc tatattcatt agatacaaac cccctcagac atgattataa
    12661 catataattt ataaagatta ataaaataaa aaaaaagttt tacaatacaa gtatttttta
    12721 tgctatattg aattttctga aaagatgcat tataatagta ttaatattca atatattgaa
    12781 tattgataac gatattttaa tttaatgaaa tggaggtaat taagatgaag agttttgtaa
    12841 gtcctgataa tatttgggta ttatgggcag ttgtaactgg atgggcagca tttagtattt
    12901 atttggaaca aaagtacaat tgggcatcaa aagtgtcggg agcaataata gctcttgtag
    12961 gagcaatgtt attatcaaat ctaaatatta taccagtaga gtctgttgta tatgaccaag
    13021 tatggggata tgttgttcct ttagccatag ctttattgtt atatcaatgt aacattaaaa
    13081 agatatggaa agaaagtgga agattgctca ttatatttct tgtaggttct gtaggaactg
    13141 tacttggagc tatgattgga tttttggcat taaaaaatgt agtaccagat ttaaatattg
    13201 ttgcagctat gatgacaggt tcttatatag gtggaaatgt aaactttgct gctatgtcag
    13261 gcgcgtttga tgcgccagga gaattagtat cagcaacagt tgtagcagat aatcttttaa
    13321 tggcattata tttctttgtc ttaatagcta taccatcaat tggatttttt agaaaacatt
    13381 ttaaacatcc acatgtagat gaaatggaaa gtataggtat aactgaagga gaaacagtag
    13441 cagcaaatta ttggggaaga aaagaaatat ctttaaaaga tatagcaata gccattggta
    13501 gtgcttttat aattgtcgca gtatctgtag aactatcaac ttggtttaaa gctataatac
    13561 cattatcaaa tcctttttta gcaatgttaa atactttatt tggaaatcaa tatctaataa
    13621 taactacttt gactatgttg tttgccacat ttatgcctaa tttctttggt gatataaaag
    13681 gagcacagga attgggtaca tttttaatat atatattctt tgttgtagta ggtgttcctg
    13741 cttcaataac attaataatt caaaaatcac cattactact tttatactgc ggaataatgg
    13801 tactaataaa catgctagtt acatttatag ttgcaaaaat atttaagttt agtttagaag
    13861 aagctattct tgcatctaat gcaaatattg gtggtcctac aacagcagca gctatggcaa
    13921 tatcaaaagg atggtctaag ctagtagggc caatacttat agttggaaca tttggataca
    13981 tagtcggtaa ttattttggt cttttagtag gaaatatttt gatataattt tacgtgaaaa
    14041 aaagttgttt tttagaaaga tttttattta ttagaaagat ttttatttaa ttggaggttg
    14101 ttatgatttt cgatggacat tcagatactt gggcagatgt aacaataaga aggcttaacg
    14161 gggaaaaaga tgtatttaga agaatccatc ttgataattt taaaagagca aatatagaag
    14221 gagctatttt tgtaatatgg atagacccac catatgataa agagcctgaa aaaagagtta
    14281 aacaaattat aagctctata aaagatgaaa ttgaagatat gaaagatgtt gtaaacatag
    14341 taaaaaaata ttcagatata gataaaggta taagtgaaaa caaaataaat attttaattg
    14401 gtcttgaagg attaagccat attggaagaa atatagattt actagattat ttttataaag
    14461 aagttggtgc aagacatgca tcattaactt ggaatgaaca gaatgaactt gctacaggat
    14521 gtttagggga tgaaaatcgt ggtttaactg aaataggtaa aaaagcagtc aataaaatgg
    14581 aaaaattggg catgatagta gatgtgtcac atttaaatga aaaatcattt tgggatttaa
    14641 tgtctgttgc aagtaagcca gttatagctt ctcattctaa tgctaggagt ttatgtgatg
    14701 ctaaaagaaa tcttacagat aatcaattaa aagaaatttc aaatacaggt ggattagttg
    14761 gaataaatag ttttagagga tttactaata gtaatcctaa gaagcaagat ttaatacatt
    14821 tggttgacca tatagactat atggtaaatc ttataggtat agaacatgta tcttttggtt
    14881 ttgattttag cgattactta gggaaagaga ctataggttc ttttactgga aatgctagtg
    14941 tgccaagtgt agatggtctt gaaagcacac atacagcaca gaacatagta gtagagcttg
    15001 aaaatagagg ttataaaaag aaagatatag agttaatctc tagtggtaat ttttataggc
    15061 tctttaaata tatactaaaa taatataata aagaacttaa atttataaaa tagtatattt
    15121 atacaaataa tatctacata tttaaattgg cgttcataat ttattaaatt aaattttaat
    15181 gttactagaa gtttcaattc tagtaacatt ttttatgtta aaaacagata tagatatgta
    15241 ttgacaatga taattattat tgataaacta taaaagtgaa aatgataata attttcattt
    15301 taattaataa aagattttta aggagggaga atgaagaaaa ggtatttagt cataggaata
    15361 ataattttgt cttatttttc tttatttata ggagctgaag atataaatat aatgcatata
    15421 tttgccaaaa atcagcataa acttatgata tttatcatga gtagaatacc aagattaata
    15481 agtatattga ttgctggtgt aggaatgagc atagcaggtc ttataatgca acagataagt
    15541 aagaataaat ttgtatcacc tacaacaggt gctacaatag atgcagcaca atttgggata
    15601 gtaatatgta tgcttttagt accaactgcc tctattttta caaagacaat aatagcattt
    15661 gtattttctc ttgtagggac ttttacgttt atgaaaataa tagggaagtt acaatttaaa
    15721 aatataatct ttgtaccatt agtaggtata atgtttggaa atataatagg ttctatgacg
    15781 gattttatcg cgtataaata cgatttgagt caaaatgtta gttcttggat gcaaggtgac
    15841 ttttctatga tacttaaagg aaattatgag atattatata tcacaatacc ccttataata
    15901 ttagcatata tttatgcaaa taaatttact gttgttggta tgggtatgga ttttgcgaca
    15961 aacttaggtc ttagttacaa aagaattgtc aatataggtc tgataatagt agcacttgtt
    16021 acagtatgtg tagtcgttac agctggtaat atccctttta taggtctaat agttccaaat
    16081 atcgtatcct tgtatatggg tgataatata agagcaaaca tatggtatac tggtttactt
    16141 ggagcgatat ttgtacttat atgtgatatt tttggaagaa ttattattta tccatatgaa
    16201 atatctatag ggcttacagt tggagttata ggaagtatac tattccttta tttaatatta
    16261 aggaggaatg taaatgaagc ttagtctcaa tcaaaaaatt tactttgtaa gtatattact
    16321 attcatatca atagcacttt ttataattta tggaatagac atgaatcatt tagaatatgc
    16381 attatcacaa agaataccaa aaatatttgc tatggtatta ggtggaggat gtatagcatt
    16441 tactactgta gtgtttcaaa caattacaaa caatcaaata ttaacaccaa gtgtactagg
    16501 tttagattca ttgtatgtaa tgattcaaac tataatagta ttcatatttg gttcaagcag
    16561 tagtctgatt ataaatgaaa attataattt tattattaat gtagctatga tgattggagc
    16621 ttcattgtta ttatataaga tgttatttga aaaaaataaa aataatattt tctttttaat
    16681 cctagtagga atgatatttg gaaccttatt taaaagtgca acaacattta ttcaggtaat
    16741 gatagacccg aatgaatttt tagctttaca aactagtata atggcaagtt taaacaatat
    16801 aaacactaat gtattgttaa tagcatttat aataattatt gccataatac cttttatata
    16861 tgatgaaata aagtatttag atgtattgtc gttaggtaaa gaacaagcaa ttaatttagg
    16921 tgtagatttt gataaagcag ttaaaaaaat gataatatta atagcaattt tagtctcaat
    16981 atcaacagca cttattggac ctatgacatt tttaggactt ttacttgcta atataacaag
    17041 agaaattttt aaaacatata agcatacata cttgatttcg ggttctatgt tgatagggat
    17101 gattacattg ataataggtc aattttttat acaacatgta tttaagtttg atacaacttt
    17161 aagtgtagta ataaatttta taggaggaat ttactttatt caattactat taaagggggc
    17221 aaatagatga tagagataaa aaatatattt aaaagatata agaataaaaa tgttgtagat
    17281 gatgtctctt ttagtataga aaagggaaag ataacatctt ttataggacc aaatggagct
    17341 ggaaaaagta cagtactatc aatagttaca agacttatag gaggtgatgg tggagaagta
    17401 ataatagaag gaaaaagctt gactaattat agcaataaag aattagcaaa aaaaatagct
    17461 attcttaaac aatctaacaa tataacttta aagcttacaa taagagaatt agttggattt
    17521 ggaagatttc catatagtga aggtaatcta actaaagagg atgaaaatta tattgatgaa
    17581 gcaatagaat atatgaagtt gactgatata caacataagt atttagatga attgagtgga
    17641 ggtcaaagac aaagagctta tatagcaatg gtaatagctc aagatacaga gtacatatta
    17701 cttgatgaac cactgaacaa tttggatatg aaccattccg tacagatgat gaaggtactt
    17761 agaagtcttt gtgatgagtt agataagact atagtattag taatgcatga tataaatttt
    17821 gcatcatgtt attcagataa tatagttgca ttaaaaaatg gaaaagttga aaaagtaggt
    17881 cgtacagatg agatagtaaa tgaaaaagtt ttagaagata tttatgagat gaattttaac
    17941 attaagaata taaatggaaa tcgaatctgt atttattttt aaaatattgt atatgaaaat
    18001 aaacttgcta tataattttt tataaagttt ttaaattaaa ataaagatta ataggagaga
    18061 ggaaaatatt gatatgaata aaaaagcagc aatagtagca gcagtagcta ttataggatt
    18121 agtgacagtg tttgcattag gtggaagtaa aaagaatgaa tcaaaaacat cagaaaattc
    18181 aaataatacc ataaagataa ctcataactt gggagaaaca gatgtaaaat taaatcctaa
    18241 aaaagtagta gtatttgatt attcggcttt agatacaatg gatgcattag gtgtagctga
    18301 gaatttagta ggacttccaa aagcgagttt accagcatct ttagaaaaat ataaggatga
    18361 caagtatgca gatttaggag gattaaaaga accagattta gaaggtataa agtcggcaaa
    18421 tccagattta attataataa atggaagaca agaagatttt tatgagcaat tgtcaaaaat
    18481 agcaccaaca ataagtacaa gtaaagatga taagaagtac ttagaatctg ttaaaaataa
    18541 tatagacaaa atagcaaaaa tatttggagt agaagaaaaa gcaaatcaag aatttagtaa
    18601 aattgaaaag aaaatagaaa ctttgaataa aaaagtaaca gataaaaatt taaatgcttt
    18661 aactataatg gtaaatgaag gtaatttaag tgtatttggt gaagaatcaa gatttagtat
    18721 attatacaat agttttggat ttgaaaataa agataaaaat ataaaagaat caagtcatgg
    18781 acaaaatatt acttttgaat atatagctaa acaaaatcca gaagttatgt tcgttataga
    18841 tagaggaata gctactggca gtgatgtaaa agaaagctca actgcaaaat ctgttttgaa
    18901 caatgatata ataaaatcta tggatgcata taagaatgat aatataatat atttagattc
    18961 accaacatgg tatgtaaatg atggtggtct aacatcttta aataaaatga tagatgatgc
    19021 ttcaaaagcg gtaaattaat aatccaatat aaccaaaatg tattttttat aaaatgatta
    19081 tcaaataaac taggagtttt taagaactcc tagtttattt tttgcataaa aaagatatag
    19141 tttaaacaat aatattatct ataataagat aaatctattc aaaatctaat aaaatatgaa
    19201 gttatactag acaaaaagaa taactcttaa atataa
//
LOCUS       DAMJXI010000065        19221 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.067, whole genome shotgun sequence.
ACCESSION   DAMJXI010000065 DAMJXI010000000
VERSION     DAMJXI010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19221
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.067"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            318..1511
                     /gene="nifV"
                     /locus_tag="PC465_002959"
     CDS             318..1511
                     /gene="nifV"
                     /locus_tag="PC465_002959"
                     /EC_number="2.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase"
                     /protein_id="HDF2650243.1"
                     /translation="MCVISKDRAKEIKIVDTTLRDGEQTAGVVFANREKIMIAEMLSD
                     LGVDQIEVGIPTMGGDEKNVIKHICSRNLKSDIMAWNRAVIKDVEESISCGVDAVAIS
                     ISVSDIHIENKLRTSRGWVLENMAKTVEFAKKNGLYVSVNGEDASRADIDFLTEFINV
                     GKQAGADRFRYCDTVGVMNPFSIKNAIETLYERTNFDIEMHTHNDFGMATANALAGIA
                     AGANYVGVTVNGLGERAGNAALEEVLMALKCVYKCDLNNIDTRKFRGICEYVAQASGR
                     ILPTWKPVVGDNMFIHESGIHADGALKDPHNYEPFDPSEVNLERKIVIGKHSGRAAVV
                     NKLSEYEMYISPENATKLLNAIRATSIRLKRSLMDKEILQLYCDILAHEKGTTEEEAV
                     RGSYI"
     gene            1536..3461
                     /locus_tag="PC465_002960"
     CDS             1536..3461
                     /locus_tag="PC465_002960"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HDF2650244.1"
                     /translation="MGDNIVYKIIKKHIVDGEAVAGSSIGIKIDQTLTQDSTGTMTYL
                     QLEAMGIDKVKTKRSVAFVDHNMLQQGFENADDHKYIQTVADKYGVYFSKPGNGICHQ
                     VFLERFSTPGDTLLGSDSHTPTAGGVGMMAIGAGGLDVALAMAGGAYYIKAPKVCKVN
                     LVGKLNNMVSSKDIILEVLRKQTVKGGVGKVYEYGGEGVKSLSVPQRATITNMGAELG
                     ATTSIFPSDEKTLEFFKSQGREEAWIELKPDADAVYDEEITINLDELKPLAAKPHSPD
                     NVDEVENIGKIKIDQVAIGSCTNSSYEDLMKVAQILKGNKVHKDVSLVIAPGSRQVME
                     MIARNGALADIISAGARILENSCGPCIGMGQSPGTDSVSLRTFNRNFYGRSGTLSAQV
                     YLVSPEVAAVSAIKGVLTDPREFDIKFTNLDVNEFLIDDSMIIKPADVGSDVEVVRGP
                     NIKPFPLNTELSQSIGGKVILKTEDNITTDHIMPSNAKLLPFRSNIPYLANYCFNTVD
                     TEFPQRAKDNNGGFIVGGDNYGQGSSREHAALAPLYLGVKGVIVKSFARIHKANLINS
                     GIIPMEFCDEKDYENISLLDNLEIPNILDNLGSGILEVKNTTKGTSFKVKVELSAKEV
                     DVLKAGGKLNYTKNQAN"
     gene            3483..4478
                     /locus_tag="PC465_002961"
     CDS             3483..4478
                     /locus_tag="PC465_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HDF2650245.1"
                     /translation="MYKVTLIPGDGIGPEVAKAMKKVVEATGVEIEWEEVNAGEAVIE
                     EYGTPLPEYIIDSIKKNKIAIKGPITTPVGKGFRSVNVTLRQALDLYVNLRPIKSFKG
                     IKSRYEDVDLVVVRENTEDLYAGIEHKIGDYAAESIKIITRSASERIVDFACNYVKDN
                     KRKKVTAIHKANIMKMSDGLFLDVFREVASKHGVEYDDLIVDAAAMNLVLNPENYDVM
                     VMPNLYGDILSDLGAGLVGGLGIIPSANIGKDCAIFEAVHGSAPQIAGQNKVNPTALI
                     QSSVMMLRYLGEYENAQKIETALEKVFLEGSKLTVDLGGSASTTEFADEVCKYIV"
     gene            4804..5277
                     /locus_tag="PC465_002962"
     CDS             4804..5277
                     /locus_tag="PC465_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2650246.1"
                     /translation="MVVSVEVCLIKTLDSNILREVGTLSRAVNSINDIKYKELKLQKG
                     QFTFLTRICENPGINLVELSNMLKVDKATTTKAIQKLIKAGYVDKKQDEFDKRGYNLT
                     PTDKSLEVYELIIEEENRSIEICFDNFTDEEKQVVTKLLEKMSKNVENEWFKVKR"
     gene            5311..5805
                     /locus_tag="PC465_002963"
     CDS             5311..5805
                     /locus_tag="PC465_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2650247.1"
                     /translation="MIRKANMNDLESIMKIIKSTVEEMKTYNNTQWDENYPLEKDFVS
                     DIKKQDLYIYEVDGEVAGFICLNYEEPEEYLGLNWSSNKKAMVIHRMAVNPNFRKTGI
                     ASKLVDFAEKLAVENNVSYLKSDTYSINSKMNLLLTKCGFIKIGEMSFLGKEKSFYCY
                     DKIL"
     gene            5902..6423
                     /locus_tag="PC465_002964"
     CDS             5902..6423
                     /locus_tag="PC465_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HDF2650248.1"
                     /translation="MIGFLKKRRSIRKYKDVEVEKEKLDKILKAALLAPSSKGLRTWE
                     FIVVDDKEKLINLSQCRTKGGGFFLKNAPLAIVIIADKEKNDVWIEDASIAASYIQLQ
                     AHELGLGSCWIQVRNRMHDDNIEADKYIREELKVPSKYSVECIISIGYPDEEKKAYSD
                     SDLDYKKVHFNNF"
     gene            6612..6923
                     /locus_tag="PC465_002965"
     CDS             6612..6923
                     /locus_tag="PC465_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF2650249.1"
                     /translation="MGIFKTKMDEDWKVNYIKEFNEMRDSYESKLQKKQFEVDSLKSE
                     LDRLRSYKNSLKPKEKQITDDDINNIKSLRRDGLSYKEISNQTSWSKATVSRVLNGLY
                     D"
     gene            6951..7637
                     /locus_tag="PC465_002966"
     CDS             6951..7637
                     /locus_tag="PC465_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2650250.1"
                     /translation="MKYSYKKCIIDSILLMFIVQILRMILNYVLLSQFEFTLENFNII
                     NLISFTLVGLSLILFLKDNSLYNKVRNRKITEAFEENKNNILIEKCKLILFVVVLSLA
                     IIVTYCTKGYVLFNVTMMTLSVLIVPIFEELFFREYIWNYLSNFIKSKSKIICITSIL
                     SGIYNIGYIDVIRNYVILYNNSSYTFEVIISKIMIGTVFGIVLGLVKYRFRDVGFCIL
                     LRSLFAIFIR"
     gene            7869..8753
                     /locus_tag="PC465_002967"
     CDS             7869..8753
                     /locus_tag="PC465_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HDF2650251.1"
                     /translation="MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIE
                     NVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVI
                     KNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
                     YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPYIVHKEEFEHPLKLDISSV
                     VNGEVRQNSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHG
                     DIVECKVEGIGVLKNIVD"
     gene            8852..10027
                     /locus_tag="PC465_002968"
     CDS             8852..10027
                     /locus_tag="PC465_002968"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HDF2650252.1"
                     /translation="MARELELKYGCNPNQKPSKIYMKNGELPIEVLNGKPGYINFLDA
                     FNSWQLVKELKEATGLPAATSFKHVSPAGAAVGVPLSDTLKQIYFVDDLELSPLACAY
                     AMARGADRMSSYGDFIALSDVCDKETATIIAREVSDGIIAPGYTDEALEILKGKRKGN
                     YNIVKIDENYTPEPIETKDVYGITFEQGRNEILINEDLLKDIPTDNKIFTDSAKRDLI
                     IALITLKYTQSNSVCYAKDGQVIGVGAGQQSRIHCTRLAGNKADTWYLRQHPKVLNLK
                     FKKDIGRPDRDNTIDVYLSDDYMDVLADGIWQNFFEEKPEPLTGEGKRAWLKTLTGVA
                     LGSDAFFPFGDNIERAKRSGVSFIAQPGGSIRDDNVILTCNKYNIVMAFTKNRLFHH"
     gene            10155..11009
                     /locus_tag="PC465_002969"
     CDS             10155..11009
                     /locus_tag="PC465_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650253.1"
                     /translation="MALNIRNYSLLCNQGTAKFNEDVVGINPFGAWVLDGATGLNGKN
                     LVSTESDARWYVQWWNRYLYKNINKEESLKSIINTGIIEVKKEYELRLNGFKVEKLDL
                     PSSSIVVVKFHENKVEYFLLGDCALFIKNGDSKVIKDRSICKFDNTVFYEMSKLSNLE
                     EMAFDEIRTSVMDTIVSNRLKKNTKEGYWILDFDEEAVENSIYGYIEIKKDFQLMLTS
                     DGFTSACDRYNLIKEEELIRIAEKFGIGYIHNKVRDFEDNDYKAVKVPRFKVKDDSSC
                     LYLDIYND"
     gene            11053..12288
                     /locus_tag="PC465_002970"
     CDS             11053..12288
                     /locus_tag="PC465_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDF2650254.1"
                     /translation="MKILHIITQKPNSTGSGIYLSGMIKGFEKIGHKQAVIAGIDVND
                     DVNCFPSEVSFYPVKYNCGELNFPVVGMSDSMPYESTRYKDLNIDMINRLKYQFKVNI
                     DKAMNDFKPELIICHHLYLLTAFVREMVKDIKVMSICHGTCLRQLNTIDLEKEYIIAN
                     IRKLDLIFALHENQKYDIIKTFGVSESKVVVIGSGYNDDIFYNKNYKIKDDKIKIVFA
                     GKICKSKGLIPFIKAISKLKYSKDLIEVNFAGTGSDIESYNEIVKLASKSPFKMNFLG
                     KLEQRDLAELFNRSQIFVLPSFYEGLPVVVLEALSCGTDVITTDILGVKEWIGSEINN
                     SGKIEYVSLPFMEKEGIPKDEELYDFENNLYNAIDSKIQSLLNNSNKKTSVDMSKKTW
                     DGLAYRINEVILMDELCLV"
     gene            12389..13330
                     /locus_tag="PC465_002971"
     CDS             12389..13330
                     /locus_tag="PC465_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp25"
                     /protein_id="HDF2650255.1"
                     /translation="MRISKKVLALGISALLLSVSFPTSINALDKIENIQGVDKYETAG
                     LISDKQDFTTAVLINADSTMVDGIAASGLAGVNNAAILLTNKDDIPEATLQRLNRVTK
                     IYVIGGENSISKDVEKMLLMRRMQVIRIDGVDRVDTSYKIAGEIEKIKNSDKMFLVNG
                     FKDEADAVSVASVAYRDGAPIILTKDIPSAEEDTDLDPWFGVSPVPVYAIGGESTLSD
                     YIVSRYRATRIGGVDRYQTNKNVIEKFYNGAKEFYITSGDDLVYALVASPLAKNAPVV
                     LVSNKSDKSILSGASKVTAIGISDKSIIEQCLDAVKK"
     gene            complement(13549..13902)
                     /locus_tag="PC465_002972"
     CDS             complement(13549..13902)
                     /locus_tag="PC465_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDF2650256.1"
                     /translation="MDRKRELKQLYKEMKFDIGVFIIKNDITKKIYLGKSNDIKSKFN
                     SLKFQLGAGSCMIKELNNEWKKYGEKAFIFEVLELIKHDDNKTEKDYLEELDILEMVW
                     LEKLKEDNTYEIYSI"
     gene            14198..15109
                     /locus_tag="PC465_002973"
     CDS             14198..15109
                     /locus_tag="PC465_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="HDF2650257.1"
                     /translation="MNKKIELIGNFASDWIRYSDYEYKITEEDELYIVPTEDAVFTMY
                     NPFDVADDIIVDIIRIGQEALQDISKETKEMKLKKEVLEFVKKYGLLGLIYSSVYNRD
                     IVGEERVLMIEKNYITKENILSTDEYVNMFIPFASDEDVYFKKYRRGIDVSKREESPK
                     FFGKRPLILDLVFSKFYTEQLDWIVSFAKDMCKHFNQICVYKNTSNLLTESVTIMSGG
                     FNPQKIGFSISQLDKPIIAWEFDSLKTAIETIYAFAITSEPSSLNKCKYCGKIYIPTN
                     SKSQYCSPSCRNCSNVKKSRSRAKKDK"
     gene            15370..15804
                     /locus_tag="PC465_002974"
     CDS             15370..15804
                     /locus_tag="PC465_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650258.1"
                     /translation="MISPIILSSINQNLKEIERNELLETNIESGDYGLALSESDVKDI
                     INSRDNTLKGYGRIELDIKVTKQLIENIYTSQYTNVDNYLEAINDMQEIFYYLKNETD
                     DKICDDEIIEILGEFYEKFSGNMDNVRGEADEFAKKFKFGEV"
     gene            15827..17362
                     /locus_tag="PC465_002975"
     CDS             15827..17362
                     /locus_tag="PC465_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650259.1"
                     /translation="MLNNLSNININENNLIKNQYSISLLKECLNCKVIDEREVYNIQQ
                     EISLILMDLIKKYTNGQSTSVKTEVAEKLLISIWYAIDAYINKLGDIEKRVVELTAKN
                     VKKVYLGGIEILEEELVRLKDFYKLMMSRKLDTNSIAYNDTLMELSSFFKSYIVKFEA
                     QDVPVSIDYPLALDDMDVKGIYYVKNYIESIDIENRFCNLFKKKDREKLFYDYGVTYK
                     IDCDVVLVNLFELIINNCIFSTILGNEVTNLEISKYEYEFLEKQFKNMYNNITEDEVI
                     GSEESNIIELIEVDDSFNTEVDSNLDYNDFEEINREIRINKKITLLLMEAIEVLIKRL
                     SIEDEDVIRYIKKYEKIFIESVLSSIKSNTFKSMVTVSKNKKEHLEDYIVDDESKLDD
                     ESFREIFNEILDSTSIIEKIRIIKENINAKKDFIDILESECLFGEEYLMLFASLSELE
                     LAILGSVVFYEDIRMREINILEFMLNEKTETTLWKIEYIKFMKRQSEDKIYSIEEHMN
                     KIN"
     gene            17446..18813
                     /locus_tag="PC465_002976"
     CDS             17446..18813
                     /locus_tag="PC465_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2650260.1"
                     /translation="MKEYIINNVEEIREELIDLSKKIWENPELAFEEKYASSIQKEYL
                     KSKGFKIEEVENLPTGFIASFGEGKPVIGILGEYDALPELSQCVSAERKPLVEGKAGH
                     GCGHNLLGVAGVGAVVSIKKLIEENKFNGTIKYFGCPAEEEGGGKTVMCINGCFDDVD
                     CAFTWHPFDINAPWRGGSLANLSVKFKFKGITAHAAQAPHNGRSALDAVEIMNVGANY
                     LREHVIDSIRMHYVITNGGGRPNVVPGFAESWYFIRGKKAKDAEHVLDRLIKVAQGAA
                     MMTETEMEYKVTDGIYDYIPNQCLTDLVYDNMVFVGCPKNTPEEEEFAKKLCDTLTRE
                     ERLGVATSLQNDKSIVESYIHKEIVDGDKDKGLAGSTDVGDVSYVIPVAQFAMAAWPV
                     GIASHTWQSCSSAGSNIGFSAMINSAKVLACSAYDVFMDTKIIDEAKIEFDKSLDGQK
                     FKPLV"
     gene            18848..19072
                     /locus_tag="PC465_002977"
     CDS             18848..19072
                     /locus_tag="PC465_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HDF2650261.1"
                     /translation="MREKVEKVLEEKIKPVLQRDGGDVELIDVNENGVVLVRLQGACS
                     GCPGATMTIKAIIENVLVSEVPGVTQVLGV"
BASE COUNT         7678 a         1820 c         3617 g         6106 t
ORIGIN      
        1 attaaatttt agtaggaatt ttataggttt atttttaaag gttttttgaa aataaatcta
       61 tttaaaaatt aaattaaaat gcaagaaaaa cataataact ttcattttta agaagttttc
      121 acaaaaaaga aaaaatatag tgcaataaat gatacaaagt aatataatag attacaagat
      181 atgaaaagct aaaaaaataa attgcaaatg aaattaaaat gaataaaaaa taaaaaaata
      241 atcataagtt agaggtatca atgaaaaata agacttaatg tttttaaaat taaaagtata
      301 ctaagggggg cattaatatg tgcgttatat caaaagatag agcaaaggaa ataaaaatag
      361 tagatactac tttaagagat ggagagcaaa cagctggggt tgtatttgca aatagagaaa
      421 aaataatgat tgctgaaatg ttaagtgacc taggtgttga ccaaattgaa gttggtatac
      481 ctactatggg tggagatgaa aaaaatgtaa taaagcacat atgtagtaga aatttaaaat
      541 cagatataat ggcttggaat agagcagtaa taaaagatgt tgaagaatct atttcttgtg
      601 gtgttgatgc agtagctata tcaatatcag tatctgacat tcatatagaa aataaattga
      661 gaacttctag aggctgggtt ttagaaaata tggctaaaac agttgaattt gcaaagaaaa
      721 atggattata tgtttcagta aatggagaag atgcttcaag agcagatata gacttcttaa
      781 ctgaatttat aaatgttgga aaacaagcag gggcagatag atttagatac tgtgatacag
      841 taggagttat gaatcctttt tctataaaga atgcaataga aactctttat gaaagaacta
      901 attttgatat agaaatgcat acacataatg actttgggat ggcaactgca aatgcacttg
      961 caggaatagc agcaggagca aattatgttg gtgttacagt aaatggatta ggtgaaagag
     1021 caggaaatgc agcattagaa gaagttttaa tggcacttaa gtgtgtttat aaatgtgatt
     1081 taaataatat agatactaga aaatttagag gaatatgtga gtatgtagca caggcatcag
     1141 gaagaatact tcctacatgg aaaccagtag ttggggataa tatgtttata catgaatctg
     1201 gtatacatgc agatggagct ttaaaagacc cacataacta tgaaccattt gacccaagtg
     1261 aagtaaatct tgaaagaaaa atagtaatag gtaaacattc aggaagagct gcagttgtaa
     1321 ataagttgag tgaatatgaa atgtatattt ctccagaaaa cgctaccaag ctattaaatg
     1381 ctataagagc tacatctata agattaaaaa gaagtttaat ggataaagaa attcttcaat
     1441 tatattgtga tatactagca catgagaaag gcacaacaga agaagaagca gttagaggtt
     1501 catatattta agatataatt gtttaggagg aaaatatggg agataatata gtttataaaa
     1561 taattaaaaa acatatagta gatggagaag ctgttgctgg aagttcaatt ggtataaaaa
     1621 tagaccaaac tttaacacaa gattctactg gaacaatgac atatcttcaa ctagaagcta
     1681 tgggaataga taaagtaaag actaaaagaa gtgtggcatt tgtagaccat aatatgttac
     1741 aacaaggatt tgaaaatgca gacgaccata agtatataca aacagtggca gataaatatg
     1801 gagtttattt ctctaagcca ggaaatggta tttgtcatca agtattttta gaaagatttt
     1861 caacaccagg agatacactt ttaggttctg atagccacac acctactgct ggaggtgtgg
     1921 gcatgatggc tattggagct ggtggattag atgttgcttt agccatggca ggaggagcat
     1981 actatataaa agcaccaaaa gtctgtaagg tgaatctagt tggaaaatta aataatatgg
     2041 tatcatcaaa agatataata ttagaagtgt taagaaaaca aactgtaaaa ggtggagtag
     2101 gtaaagttta tgaatatggt ggagaaggtg tcaaaagcct atctgttcca caaagagcta
     2161 caataacaaa tatgggggct gaacttggag caactacttc aatcttccca agtgatgaaa
     2221 aaacactaga attttttaag agtcaaggaa gagaagaggc atggatagag ctaaaaccag
     2281 atgcagatgc agtttatgat gaagagatta ctataaactt ggatgaatta aaaccattag
     2341 ctgcaaaacc tcatagccca gacaatgtag atgaagttga aaatataggc aagattaaaa
     2401 tagaccaagt ggcaatagga agttgtacaa attcttctta tgaagactta atgaaagtag
     2461 cacaaatcct gaaaggaaat aaagtacata aggatgtgag tttggtaata gcaccaggtt
     2521 caagacaagt tatggagatg attgctagaa atggggcttt ggcagatata ataagtgctg
     2581 gagctagaat actagaaaat tcttgtggtc catgtattgg tatgggtcaa tctccaggta
     2641 ctgactctgt gtctttaaga actttcaata gaaatttcta tggtagaagt gggactttgt
     2701 cagcacaagt atatttagta agtccagaag tggcagcagt aagtgcaatc aagggagtgc
     2761 ttacagaccc aagagaattt gatattaaat ttacaaattt agatgtaaat gaatttttga
     2821 tagatgatag catgataatt aaacctgctg atgtaggaag tgatgtagaa gtagttagag
     2881 ggcctaatat aaaacctttc cctcttaata cagagctaag tcagtctata ggtggaaaag
     2941 ttatattaaa gacagaagat aatataacta ctgaccatat aatgccatca aatgctaagt
     3001 tacttccttt tagaagtaat ataccgtatc ttgcaaacta ttgtttcaat actgtagata
     3061 cagaatttcc tcagagagca aaagacaata atggtggatt tatagttggt ggagataatt
     3121 atggtcaagg ttcaagtaga gaacatgcag ctttagcacc attatatcta ggtgttaaag
     3181 gggtaatagt taagagcttt gcaagaatcc acaaggctaa cttgataaat agtggtataa
     3241 ttccaatgga gttttgtgat gagaaagatt atgaaaatat atctctttta gataatctgg
     3301 agataccaaa tattttagac aatctaggta gtggaatttt agaagttaag aatacaacta
     3361 aaggaacttc ttttaaggtc aaagtagaat tgtcagcaaa agaagttgat gtattaaaag
     3421 ctggtggaaa attaaactac actaaaaatc aagctaatta atatgaaaag agggaatatt
     3481 gaatgtataa agtgacactt ataccaggag atggaatagg accagaagtt gcgaaagcta
     3541 tgaaaaaggt agtagaagct actggagtag aaatagaatg ggaagaagtt aatgcaggag
     3601 aggcagttat tgaagagtat ggtactccac ttcctgaata tattatagat agtataaaaa
     3661 agaacaaaat agctataaaa ggcccaatta ctactcctgt aggtaaagga tttaggagtg
     3721 taaatgtaac tttaagacag gcattagatt tgtatgtcaa tttaagacct attaaaagtt
     3781 ttaaggggat aaaatcaaga tatgaagatg ttgatttagt ggttgtaaga gaaaatacag
     3841 aagatttata tgctggaata gaacataaaa taggtgatta tgcagctgaa agtataaaga
     3901 taataacaag aagtgcaagt gaaagaattg ttgattttgc atgtaactat gttaaagata
     3961 ataagagaaa aaaagttaca gctatacata aggcaaatat aatgaaaatg tctgatggat
     4021 tgtttttaga tgtgtttaga gaagttgcat caaaacatgg tgtagaatat gatgatttga
     4081 ttgtagatgc agcagctatg aacttagttt taaatccaga aaattatgat gtaatggtaa
     4141 tgccaaatct ttatggagat atactatcag atttaggtgc tgggcttgtt ggaggtttag
     4201 gtataattcc aagtgcaaat attggtaaag attgtgcgat atttgaagct gttcatggaa
     4261 gtgctccaca aatagcaggt caaaataagg ttaatccaac agcacttatt caatcatcag
     4321 taatgatgct tagatactta ggtgaatatg aaaatgcaca aaaaatagaa acagctttag
     4381 aaaaagtatt tcttgaagga agtaaattga ctgtagattt gggtggctca gcttctacta
     4441 cagagtttgc ggatgaggtg tgtaagtata ttgtatagat tttatttagg gaaaaagtaa
     4501 aatatagatt gaaggaaaga ggctttctca aaatggagat aagccttttt tattggaatg
     4561 ataaaatata tttgatttta tacaaaagag agttcctcat aaacgaaaaa gttaattttg
     4621 ggatatccat tttaatttta aaattaattg attaatatgc aaagaaagat taaataaatt
     4681 tattattttt aattgaactt tcaaccaaaa tatggtaaaa tttaaaaaag ttgaactttc
     4741 aactaaaaat gaatatattg attatgtgaa attctataaa acagaaacta tttgacttta
     4801 gccatagtag tttcagtgga ggtgtgtttg attaagactt tagacagtaa tatattaaga
     4861 gaagtaggta ctttatctag agcagtaaat tcaataaatg atattaagta caaggaatta
     4921 aagttacaaa aaggacaatt tacatttttg acaagaatct gtgaaaatcc tggtataaat
     4981 cttgtggaat tatcaaatat gttaaaggta gacaaggcta caacaaccaa ggctatacaa
     5041 aaattaataa aggcaggata tgtagataaa aagcaggatg agtttgataa aagaggatat
     5101 aatttaactc caactgataa atctttggaa gtttatgagt tgataattga agaagagaat
     5161 agaagtatag agatatgttt tgataatttt acagatgaag aaaaacaagt ggtaactaag
     5221 ttattagaaa aaatgagcaa aaacgtagaa aatgaatggt ttaaagtaaa gagatagtaa
     5281 ataaatacat taacttaagg agatattttt atgattagaa aagcgaatat gaatgattta
     5341 gaaagcatta tgaaaattat aaaatctaca gtggaagaaa tgaagactta taataataca
     5401 caatgggatg aaaactatcc attagaaaaa gactttgttt cagatattaa gaaacaagat
     5461 ttatatattt atgaagtgga tggagaagta gcagggttta tatgtcttaa ttatgaagag
     5521 ccagaagaat atttaggctt aaattggtca tctaataaaa aagcaatggt aatacataga
     5581 atggctgtaa atccaaactt tagaaagaca ggaatagcat ctaagttagt tgattttgct
     5641 gaaaaattag ctgtagaaaa caatgtatca tacttaaaga gcgatacata ttcaataaac
     5701 tcaaaaatga atttattact tacaaagtgt ggttttataa aaatcggaga aatgagtttt
     5761 ttaggaaagg agaaatcttt ctactgttat gataaaatat tataaagagc atttataata
     5821 caaggggtaa ataatagatt ttcagcatta gtaagggcat aatataacct agtatatgct
     5881 attatgaaag ggatgattta tatgattgga tttctaaaga aaagaagaag tattagaaaa
     5941 tacaaggatg ttgaagtaga aaaagaaaaa ttagataaaa tattaaaagc tgctctttta
     6001 gctccatcat caaaggggct tagaacatgg gaatttatag tggtagatga taaagaaaag
     6061 ctaattaatt tatctcaatg tagaactaaa ggtggtggat ttttcttaaa aaatgcacct
     6121 ttagctattg taattattgc agataaagaa aaaaatgatg tttggataga ggatgcaagt
     6181 atagctgctt catacataca acttcaagct catgaactag gtttaggttc ttgttggata
     6241 caagtaagaa atagaatgca tgatgataat atagaagctg ataagtacat tagagaagaa
     6301 ttaaaagtac ctagcaagta cagtgtagaa tgtataattt ctataggata tcctgatgaa
     6361 gaaaagaaag catacagtga ctctgattta gactataaaa aggttcattt taacaacttt
     6421 tagtatataa tatgttgtat taagacatta tatttttttc tattgttaat atatacttaa
     6481 aattgtaaaa atatatctga attttactaa cttatctagg ggttatgtac aaggatttta
     6541 aagataaata tagaaattaa tgtttataat cgatacataa cttgagtaac aaaatttaag
     6601 gaggttaaag tatgggtata tttaaaacaa aaatggatga ggactggaaa gtaaactaca
     6661 ttaaagagtt taatgaaatg agagattctt atgagagtaa acttcaaaaa aaacagtttg
     6721 aggtagatag tttgaaatca gaattggata gactaagaag ctataaaaat agccttaagc
     6781 caaaagaaaa acaaattact gatgatgata taaataatat aaagagttta agaagagatg
     6841 gcttaagcta taaagaaatt tcaaatcaaa caagttggag caaagcaact gtaagtaggg
     6901 tattaaatgg actttacgat tagcatatac atggggtgat ttaaattggg atgaagtata
     6961 gttacaaaaa atgcataata gattctattt tattgatgtt tatagttcaa atattaagga
     7021 tgattttgaa ttatgtactt ctaagtcaat ttgaatttac tcttgaaaat tttaatatta
     7081 taaacttaat ttcttttaca ttagttggtt tatcgttaat tttattttta aaagataatt
     7141 ctttgtataa caaggttaga aatagaaaaa tcacagaagc ttttgaagaa aataaaaaca
     7201 atatacttat tgaaaagtgt aagctgatac tttttgttgt ggttttatct ttagcaataa
     7261 ttgtaactta ttgtactaag ggatatgtac tttttaatgt aactatgatg actttgtctg
     7321 tattgatagt tccaatattt gaagagttat tttttagaga atatatatgg aactatctaa
     7381 gtaattttat aaagtcaaag agtaaaatta tctgtataac atctatacta tctggaattt
     7441 ataatatagg atacatagat gttataagaa attatgtaat attgtataac aattcgagct
     7501 acacctttga agttattatt tcaaaaatta tgataggtac tgtttttggt attgtacttg
     7561 gattagttaa gtataggttt agagatgtag ggttttgtat attattgagg agcttatttg
     7621 ctatatttat taggtagata gtataatcgg tttataaggt tgttttaaat ttaattttaa
     7681 atcaacctta ttttatttgt gttttataaa gcacttatat attaataact aataaattta
     7741 ataaaaatta tttgaatatt tttaaaatat ataaatatgt attgacatat aaatattatg
     7801 aattacaatt tatataaact aataaaaatt aaataatatt aatcaactta ttgaatggag
     7861 gaataaaaat gaaatttgtg actttttgta gtagcaatga agaaaaaata ggtgtattta
     7921 attcagaaac aaatagtata tatgaaatta atagtttagg attaagtaaa ttatatactg
     7981 atatgaatga ttttattgaa aacgtatcta caggagattt agaaaaaata aaaaacaatt
     8041 catttgaaaa cgcaaagtgt tataagttag aagaagttaa attatgttcc ccaattgtaa
     8101 gacctaaaaa agatattata tgtttaggtc taaactataa agaccatgtc aatgaaatcc
     8161 cagatggagt tataaaaaac gtagttatgc cagattatcc aatttatttt tctaagagag
     8221 cagacaaaat aattggagtg gatgataaga taagcttaca tggagatttg gtagagaagt
     8281 tggactatga atcagaactt gcagtaatca taggtaaaga aggtataaat atatcaaaag
     8341 aagatgctta tgaatatata tttggatata caatagtaaa tgatataagt gaaagagcac
     8401 ttcaagataa acatgttcaa tggtttagag gaaaaagctt agacacacat acatctatgg
     8461 gaccttatat agtacataaa gaagaatttg aacatccttt aaaattagat ataagtagtg
     8521 tagtaaatgg agaagtaaga caaaattcta atacagagta ctttatattt gatataccta
     8581 ctataataaa tgatttatca agaggaatga ctctaaagcc aggagatata atttcaactg
     8641 gaactccagc aggggttgct atggggatga atcctcaagt atatttaaag catggcgata
     8701 tagttgaatg taaagtcgaa ggaataggag ttttaaaaaa tatagttgat taatggataa
     8761 atatgccata taattttatt agtacgaata atttaattaa tataggatta atcaaactta
     8821 tgattaattt attatagaga gggatgagta tatggcaaga gaactagaat taaagtatgg
     8881 ctgtaatcca aatcaaaaac catcaaagat ttatatgaag aatggagaac ttcctataga
     8941 agtattaaat ggaaaacctg gatatataaa ttttttagat gcatttaata gttggcaact
     9001 tgtgaaggaa ttaaaagaag ctacaggtct cccagcagca acttcattta aacatgtaag
     9061 tccagcagga gcagcagtag gggtaccttt atcagatact ttaaagcaaa tatattttgt
     9121 tgatgattta gagctttctc cattagcttg tgcttatgca atggcaagag gagcagatag
     9181 aatgtcttct tatggcgatt ttatagcact ttcagatgta tgtgataagg agactgcaac
     9241 tattatagca agagaggttt ctgatggtat aatagctcca ggatatacag atgaagccct
     9301 tgaaatatta aaaggaaagc gtaaaggcaa ctataatatt gtaaaaatag atgaaaatta
     9361 tactcctgaa cctattgaaa caaaggatgt ttatggaatt acttttgaac aaggtagaaa
     9421 tgaaatatta ataaatgaag acctattaaa agatattcca actgataata aaatttttac
     9481 agatagtgca aaacgtgatt taattatagc tcttattaca ttaaaatata cacaatcaaa
     9541 ttctgtttgt tatgctaaag atggacaagt aataggggta ggtgcaggtc aacaatcacg
     9601 tattcattgt actagacttg caggtaacaa agctgatact tggtatcttc gtcaacatcc
     9661 taaagtatta aacttaaaat ttaaaaagga tataggtcgt ccagatagag ataacactat
     9721 tgatgtatat ctttctgatg attatatgga tgtgcttgct gatggcatat ggcaaaactt
     9781 ttttgaagaa aaaccagagc ctctaactgg agaaggaaaa agagcatggc ttaaaacttt
     9841 aacaggagta gcacttggtt cagatgcatt tttcccattt ggagataata tagaacgtgc
     9901 aaaaagaagt ggggtaagtt ttatagcaca accaggtggt tctattcgtg atgataatgt
     9961 tatattaact tgtaataagt ataacatagt catggcattt actaaaaata gattattcca
    10021 tcattaaaat actgaaagta taaagataat atagattaag taaaaatcta caacaagttt
    10081 tgttgtagat ttttttattt gctgtataat tttaaataga actttatttt tagatattca
    10141 atttggaggt tgatatggct ttaaatataa gaaactatag cctattatgt aatcaaggaa
    10201 cagctaaatt taatgaagat gtagtcggta taaatccatt tggcgcatgg gttttagatg
    10261 gtgctacagg acttaatgga aaaaatttag tgtcaactga aagtgacgca aggtggtatg
    10321 ttcagtggtg gaataggtat ttatataaaa atataaataa agaagaatca ttaaagagta
    10381 ttattaatac tggaataata gaagtaaaaa aagagtatga actaagatta aatgggttta
    10441 aggttgaaaa attagattta ccatctagtt ctatagttgt tgtaaaattt catgaaaata
    10501 aagtagagta ttttttatta ggagattgtg ctttgtttat taaaaatgga gattccaaag
    10561 ttataaaaga taggagtatt tgtaaatttg ataatactgt attttatgaa atgagtaaac
    10621 tttctaactt ggaagagatg gcatttgatg agattagaac tagtgttatg gatacaatag
    10681 taagcaatag attgaagaaa aatacaaaag agggctattg gatattggat tttgatgagg
    10741 aagctgtgga aaattctata tatggataca ttgaaataaa aaaagatttt caattgatgc
    10801 taacgagtga tggttttaca agtgcatgtg atagatataa tctaataaaa gaagaagaat
    10861 tgatacgtat agcagaaaaa tttggtatag gatatataca taataaagta agggattttg
    10921 aagataatga ctataaagcg gttaaagtgc caagatttaa agtaaaagat gattcatctt
    10981 gtttatattt agatatatat aatgattaga ctgtataaaa ctatttaatt ttagaaagga
    11041 ggcaagtgaa aagtgaaaat tcttcatata ataacacaaa aaccaaatag tacaggtagt
    11101 ggtatatatt tgtctggtat gataaaaggg ttcgaaaaaa tcggtcataa gcaagctgta
    11161 attgcaggta tagatgtaaa tgatgatgta aattgttttc caagtgaagt aagtttttat
    11221 ccagtaaagt ataattgtgg ggagttaaat tttcctgttg taggtatgag tgattctatg
    11281 ccatatgaaa gtacaagata taaagattta aatatagaca tgataaatag attgaaatat
    11341 caatttaaag taaatataga taaggctatg aatgatttta agccagaact tataatatgt
    11401 catcatttgt accttttaac tgcatttgtt agggaaatgg taaaagatat aaaggttatg
    11461 tctatttgtc atggaacttg tttaagacag ttaaatacca ttgatttaga gaaagaatac
    11521 ataatagcaa atataaggaa attagattta atatttgctc ttcatgaaaa tcagaaatat
    11581 gatattataa agacttttgg agtaagtgaa agtaaagtag ttgtaattgg tagtggttat
    11641 aatgatgata tattttataa taaaaattat aaaataaagg atgataaaat aaaaatagta
    11701 tttgcaggta agatatgtaa atcaaaggga ctgattccat ttataaaagc tatatctaaa
    11761 ttaaaatata gtaaagattt aatagaagtc aattttgcag gtactggaag cgatatcgaa
    11821 tcatataatg agatagttaa actggcaagt aagtctccat ttaaaatgaa tttcctagga
    11881 aagttagaac agagagattt agctgagcta ttcaacaggt cacaaatatt tgtgttacca
    11941 tcattttatg agggattacc agttgtagtt ttagaagctt tatcttgtgg cacagatgta
    12001 atcactactg atattcttgg tgttaaagag tggattggta gtgagattaa taattctgga
    12061 aagatagaat atgtttctct accttttatg gagaaagaag gtattccaaa agatgaagag
    12121 ttatatgatt ttgaaaataa tttgtataat gcaatagatt ctaagataca atctttattg
    12181 aataactcaa ataagaaaac atctgtagat atgtcaaaaa aaacgtggga tggcttagca
    12241 tatagaataa atgaagttat tttaatggat gaattgtgtt tagtctaaaa ttatttaaat
    12301 tataaaaaag tgtaactatt tttacactat ttttaaatga ttttatatta tactaatact
    12361 aaatatattt gttttaggga ggtaatttat gaggattagt aaaaaggtat tggcgttagg
    12421 tatttcagca ttactgttaa gtgttagttt tccaacatca ataaacgcac tagataagat
    12481 tgaaaatatt caaggagtag ataaatatga aacagctggg cttatttcag ataagcaaga
    12541 ttttacaaca gcagttctta tcaatgcaga ctctacaatg gtagatggga ttgctgcaag
    12601 tggtcttgca ggagtaaata atgcagctat tttattaact aataaggatg atataccaga
    12661 agcaacgctt caaagactga atagagttac taagatatat gtaataggtg gagaaaattc
    12721 tataagtaaa gatgtagaaa aaatgttact tatgagaaga atgcaagtta taagaattga
    12781 tggtgtagat agagtagata caagttataa aattgcaggc gaaatagaaa aaattaaaaa
    12841 cagtgataag atgtttttag taaatggatt taaggatgaa gctgatgcag taagtgttgc
    12901 atctgttgct tatagagatg gagctcctat aatattgaca aaagatatac cttcagcaga
    12961 agaagacaca gacttagacc catggtttgg agtttctcct gttccagtat atgctattgg
    13021 aggagagtct acattaagtg attacatagt gagcagatat agagcaacta gaattggcgg
    13081 tgttgataga tatcaaacta ataaaaatgt tattgaaaag ttctataatg gagcaaaaga
    13141 gttctatata acaagtggag acgatttagt ttatgcttta gttgcatcac cacttgcaaa
    13201 aaatgctcct gttgttttag tttcaaataa aagtgataag agtatattaa gtggagctag
    13261 taaagtaaca gcaataggta taagtgataa gagtattata gagcaatgtt tggatgctgt
    13321 aaagaagtaa tggagtgtta ttagtaaaat gaatatacac attgaaaatt agtagattgt
    13381 tcattttata atggtataaa atatatggga agaggctatc aaatggagat aagcctcttt
    13441 ttcattgtta aaattatgaa aagatacttt attttatata aaaaagtatc ttatgaacta
    13501 aatgtctatt ttgagacact atctactttt cttatattat attatttttt atatggaata
    13561 aatttcataa gtattatctt cctttaattt ttctaaccaa accatctcta aaatatctag
    13621 ttcttctaaa taatctttct ctgttttgtt atcatcatgt tttataagtt ctaaaacttc
    13681 aaatataaat gctttttcac catatttttt ccattcatta tttaattctt ttatcataca
    13741 tgagccagca ccaagctgaa atttgagaga gttaaatttg ctttttatgt cattactttt
    13801 tccaaggtaa atctttttag taatatcatt ttttattatg aatacaccta tgtcaaattt
    13861 catttctttg tataattgtt ttaattcacg ttttctatcc atgattttag atacctctct
    13921 ttataattga tatgtaatat gtaagtgtaa aaatatatta catataaatt ataaagagat
    13981 taattttata tgtaaatagt ttttataaat ttaattatga attagtcatc aataaacaag
    14041 aaatttagct gtagaaatcc attataaagg ctattataaa ttttaatatg ctaaaaatat
    14101 aaaaagaata gttgacagtg tagaaaatat ggaataaact aaaagtgtaa tagtaatatg
    14161 aaattatata ttacattgaa aggtgtgaat gattattatg aataaaaaaa tagaattaat
    14221 agggaacttt gcaagtgatt ggattaggta tagtgattat gaatataaaa ttactgaaga
    14281 agatgaatta tatatagttc caacagaaga tgctgtgttt accatgtata acccatttga
    14341 tgtagcagat gatataatag tagatataat tcgcatagga caagaggcat tacaagatat
    14401 atcaaaagag acaaaagaaa tgaaactaaa gaaagaagta cttgaatttg taaaaaagta
    14461 tggattattg ggtttaatat attcaagtgt atataataga gatatagttg gagaagaaag
    14521 agtactgatg attgaaaaga attatattac aaaagagaat atattgagta cagatgaata
    14581 tgtaaacatg tttataccat ttgcaagtga tgaagatgtg tattttaaaa agtatagaag
    14641 gggtatagat gtatcaaaga gagaagaatc tccaaagttt tttggaaaga gaccattgat
    14701 tttagattta gtattttcaa agttctacac tgaacaacta gattggattg taagttttgc
    14761 taaagatatg tgtaagcatt ttaatcaaat ttgtgtatat aaaaatacat ctaatctatt
    14821 aactgaaagt gttactatta tgtctggagg gtttaatcct caaaagatag gattttctat
    14881 aagccaatta gataaaccaa ttattgcatg ggagtttgat tctttgaaaa cagctattga
    14941 gactatctat gcctttgcaa ttacaagtga accttcttct ttaaataaat gcaagtactg
    15001 tggtaaaatt tatattccta caaattctaa atctcaatac tgttcacctt cttgtagaaa
    15061 ttgctcaaat gtaaagaaaa gtagaagtag agccaaaaaa gataaataaa attaataaat
    15121 atatcattgt ttagatttta gtaaataact actgaattaa aagttgttat agaaaattat
    15181 atatctaaat gatggtattt tttttgttga gaaaattgaa aagtttaatt gagatagtaa
    15241 ttttgagttg acaaaaacca cttttaacac tactattata agtggttggc aaaataatat
    15301 atactaattt aagtatagcg taaaaaacaa aaaaagtcaa tggaaaaaat aaaaaaggag
    15361 aatttaaaaa tgatatcacc tattattttg agttctataa atcagaattt aaaggaaata
    15421 gaaagaaatg aactgcttga aactaatata gaatctggag attatggtct agctctttct
    15481 gaatctgatg taaaagatat aataaattcg agagataata ctttaaaggg gtatggaaga
    15541 atagaattag atataaaagt tacaaaacag ttaatagaaa atatatatac atcacaatat
    15601 acaaatgtgg acaattattt agaggctatt aatgatatgc aagaaatttt ttattattta
    15661 aaaaatgaaa ctgatgacaa gatatgtgat gatgagatta tagaaatact gggtgaattt
    15721 tatgaaaaat tttcaggcaa tatggacaat gtaagaggag aagcagacga atttgcaaag
    15781 aaatttaaat ttggagaagt ttaatatatg ataagagaga ttttgtatgt taaataattt
    15841 aagtaatatt aatataaacg aaaataattt aataaagaac caatattcca tatctctact
    15901 taaggaatgt ctaaattgta aagtgataga tgaaagagaa gtatataata tacaacaaga
    15961 aatatctcta atacttatgg atttgattaa aaaatataca aatggtcaaa gcacatcagt
    16021 aaaaacagaa gttgccgaaa aactgttgat ttcaatatgg tatgctattg atgcatatat
    16081 aaataagctt ggagatatag aaaaaagagt tgtggagttg actgctaaga atgttaaaaa
    16141 ggtgtacctt ggaggcattg aaatattaga ggaagagtta gttaggctaa aagattttta
    16201 taaactaatg atgagtagaa aattggatac taattcaata gcatataatg ataccttgat
    16261 ggagttatca agtttcttta aaagttatat tgtaaaattt gaagctcagg acgttccagt
    16321 aagtatagat tatccattgg cactagatga tatggatgtt aagggtattt attatgtgaa
    16381 gaattatatt gagagtatag atatagaaaa tagattttgt aacctattta agaaaaaaga
    16441 tagagaaaaa ttattttatg actatggggt gacttataaa atagattgtg atgttgtact
    16501 tgtaaattta tttgaactta ttataaataa ttgtattttt tctactattt taggaaatga
    16561 agtgactaat ttagaaattt caaaatatga gtatgaattt ttagaaaaac aatttaaaaa
    16621 tatgtacaat aatattactg aagatgaagt tataggctct gaagaaagta atataattga
    16681 attgattgaa gtagatgata gttttaacac tgaagtagat agtaatttgg attataatga
    16741 ttttgaagaa attaacagag aaattagaat aaataaaaaa ataactttac tacttatgga
    16801 agcaattgaa gtattaataa aaagattaag catagaagat gaagatgtaa taagatatat
    16861 taaaaaatat gaaaagatat ttattgaatc tgtgctaagc tcaataaaaa gtaacacttt
    16921 taaaagtatg gtaactgtga gtaaaaataa aaaggaacac ttagaagatt atattgttga
    16981 tgatgaaagt aaattggatg atgaatcgtt tagagagata ttcaatgaga tattagatag
    17041 tacatctata attgaaaaaa taagaataat aaaggaaaat atcaatgcta aaaaagactt
    17101 tatcgatatt cttgaatctg aatgtttatt tggagaagag tatttaatgt tgtttgcatc
    17161 attaagtgaa ttagaattgg caatattggg tagtgtagta ttttatgaag atattagaat
    17221 gagagaaatt aatatattag aatttatgtt aaatgagaaa actgaaacta ctttatggaa
    17281 gatagagtac attaaattta tgaagaggca aagtgaagat aagatatact ccatagaaga
    17341 gcatatgaat aaaattaatt aacaaaaaat tgtgaataaa tagaatgtta gtatataata
    17401 taatctgtaa agcatatcaa aaatacatat atttggagga aaattatgaa agagtatatc
    17461 ataaataatg ttgaagaaat aagagaagaa ttaattgatt tatctaagaa aatatgggaa
    17521 aatccagaat tagcctttga agaaaagtat gcaagtagca ttcaaaaaga atacctaaag
    17581 tcaaaaggat ttaaaattga agaagtagaa aatttaccta ctggatttat agcaagtttt
    17641 ggagagggta aacctgtgat tggcatactt ggagaatatg atgctttacc agagctatca
    17701 caatgtgtaa gtgcagaaag aaagccattg gtagaaggaa aagctggaca tggatgtggg
    17761 cataacctgt tgggtgtagc aggtgtagga gcagttgttt ctataaaaaa attaatagaa
    17821 gaaaataaat ttaatggaac aataaaatat tttggttgtc ctgctgaaga agaaggtgga
    17881 ggaaagacag ttatgtgtat aaatggctgt tttgatgatg tagattgtgc atttacatgg
    17941 catccttttg atataaatgc accttggaga ggtggaagtc tggcaaactt atctgtaaaa
    18001 tttaaattta aagggataac agcccatgca gctcaagctc ctcataatgg tagaagcgca
    18061 cttgatgctg ttgaaattat gaatgttgga gctaattatt tgagagaaca tgttattgac
    18121 tctataagaa tgcactatgt tataactaat ggtggtggaa gacctaatgt agttcctgga
    18181 tttgctgaaa gttggtactt tattagaggt aaaaaagcaa aggatgcaga acacgttctt
    18241 gatagattaa taaaagtagc tcaaggagca gcaatgatga cagaaactga aatggagtat
    18301 aaggttacag atggaatata tgactatata ccaaaccaat gtttgactga tttagtttat
    18361 gacaatatgg tttttgttgg ttgccctaaa aatactcctg aagaagaaga atttgcaaaa
    18421 aagttgtgtg atactcttac tagagaagaa agattaggtg tagcaacatc attacaaaat
    18481 gataaatcta ttgtagaaag ctatatacac aaggaaatag ttgacggtga caaagataaa
    18541 ggactagctg gttctactga tgttggagat gtaagttatg taataccagt ggctcaattt
    18601 gcaatggcag cttggcctgt tggaattgca agtcatacat ggcagtcatg ttcatcagca
    18661 ggttcaaata taggattttc tgctatgata aattcagcta aagtactggc ttgtagtgct
    18721 tatgatgtat ttatggatac taaaattatt gatgaagcaa aaattgaatt tgataaatca
    18781 ttagatggac aaaaatttaa accattggta taattttggt aataaaatat ttctgggggg
    18841 aatagctatg agagaaaaag ttgaaaaagt gcttgaggaa aagataaaac cagtattaca
    18901 aagagatggt ggagatgtag agcttataga tgtaaatgaa aatggtgtgg ttttagttag
    18961 actacaaggg gcatgtagtg ggtgtccagg agcgactatg acaatcaaag ctattattga
    19021 aaatgttttg gtgagtgaag ttccaggagt aactcaagta ttaggtgttt aatagttagc
    19081 gtttattaaa tgtatgttat acataagtat ttaataaaga agtaaaaaaa atagtgaagc
    19141 aatatatatg aaaaagtatg agaaagataa taaaacatta tagaaataat gaaatatttc
    19201 atatgtatat gaagaaataa g
//
LOCUS       DAMJXI010000066        18808 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.069, whole genome shotgun sequence.
ACCESSION   DAMJXI010000066 DAMJXI010000000
VERSION     DAMJXI010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18808
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.069"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(<1..1214)
                     /locus_tag="PC465_002978"
     CDS             complement(<1..1214)
                     /locus_tag="PC465_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HDF2650262.1"
                     /translation="MRNIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFFKVRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYYNLRTITWND
                     RVSMENIRGYLPVGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNYPYQILEFTS
                     SRGCNKPYILVTFEDRIIDNCYPKCECLPIRITGPMGPRGATGSTGPTGVTGPTGSTG
                     ATGSIGPTGPTGNTGATGSIGPTGVTGPTGSTGATGSIGPTGVTGPTGNTGVTGNTGV
                     TGNTGVTGSIGPTGATGPTGVTGEIGPTGVTGPTGVTGEIGPTGATGATGVTGSIGPT
                     GATGPTGATGVTGEIGPTGEIGPTGATGPTGVTGSIGPTGATGPTGATGSTGVTGSIG
                     PTGATGPTGATG"
     gene            complement(1892..2416)
                     /locus_tag="PC465_002979"
     CDS             complement(1892..2416)
                     /locus_tag="PC465_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2650263.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQVMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(2481..3233)
                     /locus_tag="PC465_002980"
     CDS             complement(2481..3233)
                     /locus_tag="PC465_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF2650264.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(3264..4562)
                     /locus_tag="PC465_002981"
     CDS             complement(3264..4562)
                     /locus_tag="PC465_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HDF2650265.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEDIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMDDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINVSQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(4579..6843)
                     /locus_tag="PC465_002982"
     CDS             complement(4579..6843)
                     /locus_tag="PC465_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HDF2650266.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(7098..7916)
                     /locus_tag="PC465_002983"
     CDS             complement(7098..7916)
                     /locus_tag="PC465_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF2650267.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(7909..8607)
                     /gene="cbiQ"
                     /locus_tag="PC465_002984"
     CDS             complement(7909..8607)
                     /gene="cbiQ"
                     /locus_tag="PC465_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HDF2650268.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(8610..8894)
                     /locus_tag="PC465_002985"
     CDS             complement(8610..8894)
                     /locus_tag="PC465_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2650269.1"
                     /translation="MSAKTKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEI
                     TKINPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(8884..9636)
                     /locus_tag="PC465_002986"
     CDS             complement(8884..9636)
                     /locus_tag="PC465_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HDF2650270.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAIPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(9818..10010)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(10142..11914)
                     /locus_tag="PC465_002987"
     CDS             complement(10142..11914)
                     /locus_tag="PC465_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HDF2650271.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(11928..12857)
                     /locus_tag="PC465_002988"
     CDS             complement(11928..12857)
                     /locus_tag="PC465_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2650272.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            13085..13273
                     /locus_tag="PC465_002989"
     CDS             13085..13273
                     /locus_tag="PC465_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2650273.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRTKRRKEVQYE"
     gene            13266..13967
                     /locus_tag="PC465_002990"
     CDS             13266..13967
                     /locus_tag="PC465_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2650274.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHCGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDCIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            13969..14892
                     /locus_tag="PC465_002991"
     CDS             13969..14892
                     /locus_tag="PC465_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2650275.1"
                     /translation="MNTSVYLLLILVLSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            15049..15972
                     /locus_tag="PC465_002992"
     CDS             15049..15972
                     /locus_tag="PC465_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2650276.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVIVISSQLCNDTLEDYFKKITGGEGIA"
     gene            15965..16702
                     /locus_tag="PC465_002993"
     CDS             15965..16702
                     /locus_tag="PC465_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2650277.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPTKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANIALGRRK"
     gene            16713..17486
                     /locus_tag="PC465_002994"
     CDS             16713..17486
                     /locus_tag="PC465_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2650278.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYIDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETNLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIISLLLCACLSAFILKGLKHNEKN"
     gene            complement(18027..18635)
                     /locus_tag="PC465_002995"
     CDS             complement(18027..18635)
                     /locus_tag="PC465_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDF2650279.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFAISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
BASE COUNT         5960 a         3310 c         2375 g         7163 t
ORIGIN      
        1 tctcctgtcg ctcctgttgg gcctgttgct cccgttggtc ctatacttcc tgtcactcct
       61 gttgagcctg ttgctcctgt tgggcctgtt gctcccgttg gtcctatact tcctgtcact
      121 cctgttgggc ctgttgctcc cgttggtcct atttctcctg ttggccctat ttctcctgtc
      181 actcctgtcg ctcctgttgg acctgttgct cctgttggtc ctatacttcc tgtcactcct
      241 gtcgctcctg ttgctcccgt tggtcctatt tctcctgtca ctcctgttgg gcctgttact
      301 cccgttggtc ctatttctcc tgtcactcct gttgggcctg ttgctcccgt tggtcctata
      361 cttcctgtca ctcccgtatt tcctgtcact cccgtatttc ctgtcactcc cgtatttcct
      421 gtcggacctg ttactcctgt tggtcctata cttcctgtcg ctcctgtact tccggttggg
      481 cctgttactc ccgttggccc tatacttcct gttgctcctg tatttccggt tgggcctgtt
      541 ggtcctatgc ttcctgtcgc tcctgtactt ccggttgggc ctgttactcc cgttggtcct
      601 gtacttcctg tcgctcctct tggtcccatt ggacctgtaa ttctaattgg aagacactca
      661 catttaggat aacaattatc tataattcta tcttcaaatg ttacaagtat atacggtttg
      721 ttacaacctc tactagatgt aaattcaaga atctgataag ggtaatttaa agataaagct
      781 aacccataat taggatattt attcattgcc catgctttta tagttcctgt aatatttaaa
      841 caaatatagt tggatgtatc acttatccca actggtaaat atcccctaat attttccata
      901 gacactctat cattccatgt tatagttcgt aaattataat attcacttat tcttttaatt
      961 tcaatatcta ctttttcttt aaaaatatga ttcttatttg aatcaatatg aataaataac
     1021 tctgctttta atatactttt gtcttttaat atatctggta ttctcacttt aaaaaaagta
     1081 atcaactttt cttttacaaa actatttgaa catttacttc ctattaagca ataatctaaa
     1141 ttactaaagt ttttatctgg atatttttta gatataaaag tatcatcatt taaataaagt
     1201 ataatatttc tcatttataa tccctccatt ttgggtctat atcatactat gtttaaaata
     1261 catgcttagt tacaatataa ttaaaattta tagtattaaa tttttatata ataatgctga
     1321 tttctacaaa aaaagaacat gtcattagaa atttctaata gcatgttctt tttcattatt
     1381 atatattaca ctttaaatta ttccttgact ggcttagctg gtgtaaacta aaccagtctt
     1441 tctaaaatat taagcacttt tttcttatta tgttttttag gatttattgt ctatattatt
     1501 gtaaaccaaa gttataaaat tgtaaataga atatattacc ataacaatat ctttttataa
     1561 gtaaaaatta taaaaaacct tatttttatt aaatagaata aataaaataa gtttaaaaaa
     1621 tactgaaata agtgttttcc acatatttta tatatttatt taatacatta ttatttaaaa
     1681 ataaatatat aaacaatcat aataaaattt ttttaataaa actttatttt ttagttaaaa
     1741 tcatacaata tatagatttc cacaatacaa ataaattaaa aagtgaaatg tatttgtcta
     1801 aaaacataat aacatttcac tttatcctca tttttaagta atatatattt ttaattttta
     1861 tttataacta aatctagttt ttatataaat tttagttttt ttctacatct gagtaatcta
     1921 ttccaaaagt ttctacagta acagatttca taacttgtgg agtttgtggc ttatcagctg
     1981 aatctgttct aactgatgct atttcatcaa ctgtatccat accttctatc actctaccaa
     2041 aacctgcata ctgaccatct aagtgtggtg agtttttatg cattatgaaa aattgagaac
     2101 cagctgaatt aggtgccata gttctagcca ttgatatgac tcctctttca tgttttaaat
     2161 tgttagtaaa tccattacca ctaaattcac cttttattga gtgacctgga ccacccattc
     2221 ctgtaccatt tgggcatcct ccttgtatca taaatcctgg tattactcta tgaaatatta
     2281 ttccattgta atatccttca tttactaatg atacaaagtt tttaactgta tttggagcta
     2341 tatttggata taactcaatt ttgatttctt ttccattttc catttctata gttactatag
     2401 gatttttatt ttccataatt tattaccttc cttttcatta gttaaattac ataattacat
     2461 ttattatatt atactctaaa ttaaagtcta tcaagtatat tttttcctat ttcatatcct
     2521 tcttgataaa tagttttaca aaactcatca tcaaagttaa gcgtgtcttt aggagcaaat
     2581 tgagtattag gtctaactac tattatttta tcttcatcat atactttttt aatatcttct
     2641 ggcaactcat aattatattt tgtggatatt aaaataattt tatccacatt atccccaatt
     2701 aatggttcaa ttaatgcact cctaattaaa cctccatcta atttgaaacc atcataaatt
     2761 ccttcttgca catctttcac aaattgttct ttaaatccaa gagttgcgtt tggatttgat
     2821 ggtaacaacc cactgtatga aatgctgata atggcttcat tacgaggcat ttttgatacg
     2881 tcaacaatct tttctgatac tactttatta tcaacttcaa cataattaac ataaaagttc
     2941 atttcttcta tattactatc atctagttcc cttaggttgt ctatagcagg agaattatcc
     3001 acagtattat ttactatttt tacatttcca ttctggatat cttttatatt tgtccacatt
     3061 ttctccaagt tatcaacatt ccctgtgtac aaataatatc catttattgc tcctattgat
     3121 gtccctgaaa tcgaataaaa tttatttatt cctccatcat acaaggcttt aactactcct
     3181 gcttgataag ccccttttgc tcctccacct tctaaacata atcctaattt catagtctca
     3241 tctccaaatt gtttatctta tatttatatt tcaaaaaact tactaaatgt tttatatata
     3301 ctatagtggt cctcaacatt tcctaattct cttatagaat gcattgctaa aattggactt
     3361 cccacatcca cagatggtat atctatatga gtagaagata ttggacctat agtacttcct
     3421 cctctttcat ctgacctatt aacaaattct tgatactcaa cattagcttc tctacatata
     3481 tttttataaa tagctataga atatccatca ctagtatatg cctgactaac atttatcttt
     3541 ataaccggac cttttcccat tattggttta ttagttgggt catgcttttc tggaatgttt
     3601 ggatgaatag catgagctaa atctgatgat atcataaaag atgaataaat agactcaaag
     3661 aatccctctc tatccttacc cattgatatg caaattctct ccaatatatt taacaacatg
     3721 tttgaatctg caccttgttt agtagagcta ccaacttctt cattgtcaaa tacagccatt
     3781 acatttacac catgttgacc tttagtatta acaagagcat tcaaactagc atgtaccatt
     3841 gcaagattat cttgtctccc aatagatata aattcatcat tagcccctat taaacttcct
     3901 ttttcaaatt catataaaaa taaatcaaaa tctataatat cgtccatatt tacatctaag
     3961 ttagatgcta tttgctttat aagaaaatta tctttttcta atgtatcatt taacatccca
     4021 actaaaggta acatatcttt ttgcttatta tatgaatgac catcatttat acttctattt
     4081 aaatgtattg ctagatttgg tattatacaa attggctttt taaagtctat aagcctttca
     4141 tttggtttta atatactatc accttttaaa actactctac cagctatccc aagaggtcta
     4201 tccaaccatg tacttaatat tgctcctcca tagcattctg tatttaactt caaataagat
     4261 ttttcagctt ctatttctgc atttggttta atactaaatg taggagaatc tgaatgagag
     4321 cctattattc taaatccatc tctttctata tcttctgaat ttactacaaa agctactata
     4381 gctgataaat tcttagtaac ataatacttt ccaccaactc ttagattcca tctttgattc
     4441 aaaactaatt cttcaaatcc atttttatct aagatttcct tagtactctc gactgcatga
     4501 aaagacgacg gactatcata tatgaagtct attaagtttt tagcaaagtt tatactatcc
     4561 attcctcatt tacctccatt ataaaatatt tagtgttgta tattctttat ttattttttt
     4621 aattccctgt tggtcaaaag ctatagtaac atctgtacca attatagaaa ccactgtccc
     4681 aaccccaaat ttaggatgat gtaccttaga accaagtttt atatcatctg gattagtttc
     4741 tttattagaa tcttttattg tagcattaac tttatctgca actttagatt tgcttatagt
     4801 actcatatac tttttagtat atttatctaa catattataa cttgctttag aatagcttag
     4861 ttcttttttt actttgtaca atctttctat acattcttct ggcagttctt ccataaatct
     4921 tgaagctatt gcaacatttg ttttaccata taatgttctc ttctctgtca atgacatata
     4981 tagctcttct ttagctctag ttataccaac ataacaaagt cttctctctt cttctatttg
     5041 tgaatcactc atagatttta tagctcttga tataggaaat aacccttctt ccatacctgt
     5101 taaaaacaca acagggaact ctaaaccttt ggatgtatga attgtcataa gcgaaaccct
     5161 atcattgtct tcttcatcat ttgattcaga tgtaagtgct atacttgtta ggaatgtctc
     5221 taagtcttta ttttcataag tatcatcatt actactttca aactccaaag ctatagaaat
     5281 aaattctctc aaattatcaa ttctgtcttg agcttcttca cctttgcctg ttaaatcttt
     5341 ttcattttta tttcttatct ctacaagctc gtccatatat cctgtagtat ccaagacttt
     5401 ttctataagt ttgctaacag gataaacttc ttttatagtt ctaagagtcc ctataatatc
     5461 aacaaatcca cttatacttg cccttgcctt agtagatata tctgaatttg tttctatatc
     5521 aattaatact gagtatatac tttcctgttt taagttagct ctatcttcaa ttttttctat
     5581 agttctaagc cctatacctc ttctaggaac atttataatc ctttttatag atatatcatc
     5641 ttgtggattt tgaataactc ttaaatacgc caacaaatcc tttatttctt ttctctcata
     5701 gaattttgta ccaccatata tattgtatgg aatttgactt ctatttaaag cgtcctctac
     5761 aggtcttgcc tgtgcatttg ctctataaag tactgcaaaa tccttataag gtctattttc
     5821 ttttctagct atttgtgcaa ttgaatcagc aatgaaatca gcctcttcta tttcgctacc
     5881 agttaattgt atctttataa gttctccttc ttttttttca ctccaaagct tttttctttt
     5941 tctttctata ttattagata tgactttatt agctgcatct aatatcactt gtgtagacct
     6001 ataattttgt tctaacttta caacatgtac attgtcataa tctttctcaa attcaagtat
     6061 gtttcttata tctgcacctc tccatccata aatactttgg tcatcatctc caacaacaca
     6121 aatattttga tgttctcttg ctaataattt tatcaattca tattgagctt tacttgtatc
     6181 ttggtactca tctaccatta tgtatctaaa tctacttctg taatatgcta acacttcatc
     6241 attagccttg aaaagttcta cagttttaag tattaaatca tcaaagtcaa gtgcactatt
     6301 tctttttaaa cggtcttgat atagcgcata aatatctgca atcttaacca ttctattatc
     6361 tgccatattg atatctttaa actgctttgg agtataaagt ttgtcttttg ctcctgaaat
     6421 tgcacttata actgcttttg gttcaaacac tttatcactt aaatttaatt cttttagaca
     6481 gtctttaacc aatgtaactt ggtctgctga atcataaatt acaaaacttc tattgtaacc
     6541 aatcttattt atatcttttc ttagtatacg aacacagcaa gaatggaatg tacttatcca
     6601 catatcctta gtttcaggac ctatattttg ttcaactctc tctctcattt catttgcagc
     6661 tttgtttgta aatgttatag ccaatatatt tggtgcttgt acacctttat cttctataag
     6721 atatgctatt cttgttgtta ataccttagt tttacctgaa ccagcaccag ccagtataag
     6781 tactggacct tcagtctttt ctactgcttc tctttgagca ggatttaatg tatctaaatt
     6841 catatttctc ctcctgttaa cagccataaa tatattttaa tctaaaatat gaattacttc
     6901 aaattataat tatgtattat attaatagat tatttccaat atattacaat taaataacat
     6961 ttttccatat aatttatttc attgtttaat aaaaaaaata accttatgat ttggggaatc
     7021 ataaggcacc tttaaggggt ctaggttaag ggttattata tataaatcta tttttttaaa
     7081 ataggtttag ggcttaatta tttatttgta ttaagttctc tttccttcca atacttatac
     7141 aaatcttctt ctttcttaaa taagggtaaa ttcatatttc tatgtacttt tactaaccat
     7201 ggggattcta gaccagcttg tataatatta ttttcattta taaacacatt ttctgccttt
     7261 ccttcatcaa tcaaaatccc cttatccaat acatatatgt aatcacatat ttcatacatt
     7321 aaattcatat catgactgga tattactatt tttatattat ttttatttaa tccctttatt
     7381 atatctacaa tagacctagt acttactggg tctaaaccag ctgtaggttc atcaagtaat
     7441 acaatttcat tttccattgc tataactgat gctattgcca ctcttttttt ctgtccatag
     7501 ctaagaaaat gtactggcct gtctataaaa tctattccat taacagctac tagagctttg
     7561 tttattctct ctttaattgt tttttcatcc ataccaatgt ttctcattgc aaaggctata
     7621 tcatcatata cttttgaata aaaaatttgt ttttctgggt cttggaacac aatacctaca
     7681 ttttttctaa ggttgtataa acttctctta tcatatttta acttttcttc tttaaaaaga
     7741 atttctccag atgtaggctt taatataccc attaaattca taaataatgt tgattttcct
     7801 gaaccatttg aacctattat acctataaca tttccctttg aaaaatccat attaatgttt
     7861 aatagtgcat tggtattttt ttcatattga tacgttaaat tatttatttt aaacatcatt
     7921 atcccctact atgtgaaatt taccatcata caattttatg tctaatgata tacacatatc
     7981 atcatacctt gtcataagtc ttttgtacag catacttcca agaataccta aggatttata
     8041 tgaagttttt aaatttatat atccaaatct tagctcttgt gacttgtata tttctgaaaa
     8101 ttcttctaaa aatatgaata taaacctata tattaacatt gataactcga caaaagtgtc
     8161 aggtaaatga agttttttaa aaaagaatat taattgatta aaaggtgttg taagtataca
     8221 aaaatacaca caagtcaaac aagacatcgc tctaaataac acatgaatag acatgtcaat
     8281 agacgccttt gatattccta cattaaaact aaaaaattca aaactatata ataaatctgc
     8341 tttattaaaa gatatattta caagagttat tcctatacta agaaataaaa agtacattgg
     8401 tattctaagt aattttaaat aattttttaa atctattcca gccacacaaa caaccaaaat
     8461 actcattaaa atcataattc cacttaaaat aaatatattt tgtattacca tagaagcaat
     8521 cagaaaaatt actcctatgg ctactttttt gtttggattt actttactca atctatttgt
     8581 atatgcatat ttatcaatta taagcatgat taacttctct ttcctttttg aagacctaat
     8641 atgtatccta ttacaccagc ccctaaagct gcttgtgcag agaataataa actttctatt
     8701 tctccacttg gtggctcata tggactgcta aaccatggtt tgtaatttgg atttatctta
     8761 gtaatttcac tttcagcttg accatctgct cctccatatt cagcacctga gttgacaagt
     8821 aatgggaata taataagagc tactactaat aaaagtaata atatgttagt ttttgttttt
     8881 gttttagcac tcattagctt taactccttt atcattattt tctagtatgc ttttttctcc
     8941 gttttctgta attaaattat atacaattac agtaagtata ccttctgcta ttgctattgg
     9001 tatttgagtc ataaagaaaa ttcctaaaaa tttaattgct gaagccatta ccccacctga
     9061 tgggtctggg aaagccagtg ctaattgtat tgaagttatt gtatatgtgg ctaagtctcc
     9121 tattgctgct gcaagaaata ctggaatagc attatttcca tcttttttct ttaaagcctt
     9181 aaatattagg aatgatacga ttggccctat tatcgccatt gaaaaagcat tagctcctaa
     9241 agtagttatt cctccatgtg ctaataacaa tgcttggaat attaaaacta tagttccaag
     9301 aacaaacatt acgcttggtc caaacattat tgctccaaga cctacaccag taggatgtga
     9361 acaacttcct gttactgaag gtatttttag tgctgataat acaaacacaa atgctccaca
     9421 taaagctaat aatactttct ttttagggtc ttgctttact attttaccta ttgattttaa
     9481 tccgaataag aaaaatggta taaatataac tccccatgct atagaccatt ttactggtaa
     9541 gtaaccttcc attatatgca ttgcatttga tgtaactgga gttaaaatga ttaacataag
     9601 tgcagctata acccctaatt taatattctg tttcatctta gtatccctct ctccctttct
     9661 aataattaaa acataataat acatgtctga tttatttaat aaaataaaaa agcctaactc
     9721 gatggttagg cttctaattt tccacaatct aaatacaaac acataaaaca aacatatctg
     9781 tataattatt ataagaaact ttctccatcc ccgaagaaat tactttaata ttttaggcag
     9841 gtctcctgac ttagcttcat cctactcctc ttccttccca tgagatataa aaaatatcat
     9901 catagtggct aacaaaagtt tcgtctgcat cacagtagcg ggggctgtaa aggaatttaa
     9961 cctttttccc tattaatctt gcttaaagaa cctataatat tatatattta atttttaaat
    10021 tattcttaaa tcattttcta tataaatcat tgtatacctt ttctgtgaaa atttctacat
    10081 tttttataaa ttttattcat ttttatattt ttatgtatat aaattctttt ttgtaagttt
    10141 attaatttct aattatcttc tttaaataca ttgaaactac atcagaaaat ctagttatat
    10201 ctcttgaata tataaaatca tttccatata ttaatctttc agcttcaagt tctgattctt
    10261 ttcctgtaaa tactcctaat actaatatat tttgctttct agcttttctc acttcattgg
    10321 ctgtatctct caaaccaact atacccctat aagccttttc tcctcttaat gttctctcac
    10381 tactttttcc tatctttaca tcatttggtc ttccatcgct gagaactatc aggattttat
    10441 tttcttcatc tctatttatt agaccactac atatagattt tattgccaaa ccatctctat
    10501 tattaccagc acaaaaatat tcaaatatat tttcactatt ttttatacta tcatcataat
    10561 ctttaaatct ttttaatatt gtatagtcta aaaaactaga aaatcccatc actctatttg
    10621 gtatgccaac ttctgttaga gcatttgcaa ttatgtaagc ttgaattgcc acatttccct
    10681 gatttctact ttgagagcca cttgcatcca ataatatatc aataacgtat ttcccttttt
    10741 cattttctat atctttataa aatattttat tattattact tctaccaact ctccaagctc
    10801 tatttgctaa tatagtacca caatcagaat atactctact tttagcattt tcttctatta
    10861 aaattcttga cagactttct tttaatctct ttatttgctg tctatacatt ctagcatgtt
    10921 ctctaaattt tcctaaatta ttttcttttt gtcttgttac atattttagt tgaaatacat
    10981 tattacactc acttctaaga actccatctg taaagtgtat tctacaacct tcatgaacat
    11041 ttctacaatt ttgtgtctca atttttttaa tttcaccttt actcaaataa gtttttccat
    11101 aataatgttc tatttttgaa tatatcttat ttgcagtgtc ttcatcaaca tatataactc
    11161 ggtctgctga attgctacat ttagaatcat caaaatcccc tacaccttct acaagcatgg
    11221 atgaagatat tgaatctata tcactttcaa taatattttc ttcttcatca ctataaagtt
    11281 cttcatacat gaaatcagca aatgtatcaa aatttacttc tacactttct acattatttt
    11341 catcaataag actattttct tctccattta atatgtattc aaaataagtt aaatatataa
    11401 catctaatgc ttttaaaatc tccataatat cttgattggt atctatattt cttatatcat
    11461 taactattct tctagtcata ctatctaatg ctgggtgctt gtccatacta taaagtacaa
    11521 atgtgtattt aattttatcc ataatattat cattgtgtat tttggtaaaa cgtgaaacaa
    11581 tatctttata agcatttctt cttatgtctt ctatccctgg cctatcttta atgacctttt
    11641 cttcaactat tgtatttaat atgacttgaa ttagacccag tataatatct ttgttgtatc
    11701 cttttcttat tctatttgta agatattttt taactatatc ccaatctaca tactttcttc
    11761 tagcacctgc aattattgcg aaatatagac ctatttcttt tgaagagtaa tctttttctg
    11821 atatatctat actttcattg taatcaccag ctattgtcca tgataggtta ttagctctat
    11881 tttcaaattc ataatcatca tatatccatt tcataatctc acctatatta aatatgactt
    11941 attggaaaca catctatact ctcccattta ttaggtattc tagttttaat tacatctcca
    12001 accatttctt tctcatatac atcaaaagtc tttcctgtaa gtcccatatt aattgcaaga
    12061 gttggtttta atcctcttct tatagtctta agagatgcca taagaccacg taaatcaata
    12121 gctttactag atatctctcc attttgagac ttcaattgta aatctaaaaa tattcctgca
    12181 aagtgtatta atttttcttc atcagcatct gaaaattcat tttttaaaat catcattaac
    12241 ttatcttctt ctataggagg aatatctatt accataaatc tagataccag tgcttcatta
    12301 agttcttttg ttcctgcata ttcataattc atagtcccaa taaatcttgt tgctggatgt
    12361 agattgactc tctcataccc aggtacatca attattcttc tatagtctaa agctgaatgt
    12421 accacaacta tagcatcatt ttttgccata ttaatttcat caaatacccc aaaacctcca
    12481 ttaatagcac actcataaac tgagcctctt ctaagtttaa cttcattgtc tataaatgta
    12541 tctgtaccta taagtgttga actgtctgta tttatatgaa atgatgtatt ccactgaggt
    12601 ctattaaata tttcccctag attatcagca agtaagtttt ttcctgttgc ctttggtccc
    12661 gataataata tattttcttc ttctaaaata gctgctatac acatagacaa gatatcttta
    12721 ccataaaaat aagttttaga ctttgttact ctgtattcta aatctttttc taatccataa
    12781 taatttctaa aatacagtac atcttcaata agtttttcat ctaccccttg cacccttaga
    12841 ttatctatta tatccatatt tttacccctt ttatataaat agtatttgtt tcatttctta
    12901 tcaccatttt agcataaaag gatataagct aaaattgatt ttttaatctc cccattttaa
    12961 gtaaaaccat gcaccatttt atcactacaa aattaagagt actacttact gatatttctt
    13021 gattttgttc gtctatacgt atataatata tgctgataaa ttatgaggaa aggatgattg
    13081 aaatatggaa tatatgtctt gcccagaagt agcaaaaaaa tggggtattt ctgaaagaag
    13141 agtacaaaaa ctatgtgaag aaagtcgcat accaggagtt tcaaaactcg ggtatatgtg
    13201 gctgatacca aagaacgcag aaaagcctgt tgatggtaga acaaaaagaa gaaaggaagt
    13261 acaatatgaa tagcgtttta attatagatg atgacaaaga actttgtgct cttatgaaaa
    13321 aatgtgttga gcaagaaaat ttatctgcta ttactgcaca ttgtggtgca gaaggtctac
    13381 atttggtcga taaaaataga cacacactct ctcttgtaat tttggacata atgatgccag
    13441 atatagacgg ttttcaagtt ctgaaaaaaa ttagagaaac aagtaatatt ccagtaatta
    13501 tgcttactgc taaaaatgac gaggatgata aagtttccgg actacgttta ggtgctgacg
    13561 attacctaac aaaaccgttc agcataaacg aacttatggc tcgtgtcaat tctcttattc
    13621 gtcggtatac tatgttaaac cctgctttta taacagacac agattgcata ataataaatg
    13681 gcatgattat tgacaagaca aaccgaattg tttctgtcaa taatattcct gttcaactta
    13741 caagcaaaga atttgattta cttgcttttc tggcttctaa taagggacgg gtgtttacca
    13801 aaaaacagat ttatacacaa gtatgggaag aagaatatgc ttttgacgat agtaacatca
    13861 tgtctttcat cagtaaattg agaaaaaaga ttgaaccaga ccccaaccat ccattttata
    13921 ttttgacagt tcgtggtgtc ggttatcgtt ttaataagga ggcttaacat gaatacaagt
    13981 gtctatctgc ttttgatatt ggttcttagc ctgattatta tagcgtacct tgtttctgtc
    14041 ctgctacgtg tccgaataca acttacactt ataaaagatg ctttagagga tataaaaaat
    14101 ggaaacctta atcgacgtat tttaacagat gaaaacgaca ttacaaaaca aatttgctat
    14161 gatattaacg aaatagcaat caatagccaa tttcaactta ttcagcaaaa acaatcagaa
    14221 caagcctaca aacagctaat gacaagtctc tcccatgatg taaaaactcc acttgcttct
    14281 ttggtcggtt atttggaagc agtagaaagt aaaattgttg taggagagga aaaagacgag
    14341 tatatccatg ttgcgtctaa taaggctcat tacttaaaga attttgtaga aaatctattt
    14401 gaatgggtaa aattggattc taaggaacaa gtttttcatt ttgatatttt tgacttgaat
    14461 gaattatccc gtaatattat atctgattgg atacctgttt tagaaagcag tcattttgaa
    14521 tatgaatttg atataccaga aatagagtac ttcttacgta tagacgcaaa tgcatatacc
    14581 cgtatcatta ataacctatt acaaaatatt attacccata gtagtggcaa caaaatgaca
    14641 ttgagaattt ttgaaaacaa agagcaagct caaattataa taacagataa tgggaaaggt
    14701 atatcttcag acaatctccc acatattttt gaaaggttgt accaatgcga ccattcacga
    14761 gcttcaaagg gaaatggttt aggcttggcg attgcaaagg aacttattaa cgctcataag
    14821 ggaaatatta ccgccaacag cactcccggt atgggaacag aatttacaat attgcttcct
    14881 aaagccctgt aaaagtacga ggctttctta ctctaaaaca agataaaagc aagattatgg
    14941 caaggttttg gcaaggttca tgttttataa ttctaattgt agttgatttt gacgttgtat
    15001 caactatctt ttgtagaaac aaatttatta aaagtgagga aattatatat gaatgatttt
    15061 gtgattgaaa caaagcaact tacaaaaatt tatgggaatc aaacagtagt tgacaaagtc
    15121 aatctccatg taaaaaaagg ccgaatatat ggtctgttag gacgcaacgg agctgggaaa
    15181 accacaatta tgaaaatgat tttaggattg acttcaatca cgtatggcga ggtagatgta
    15241 tttggagaga atattaaggg acgtgaaaaa caggtatatc cccgtatcgg tgcaattatc
    15301 gaaacgccag gattttatcc taatctgaca ggaacggaga acttggagat ttttgcaaaa
    15361 ctgcgtggta cagccgcccc taattctgta aaaagagcat tggaaattgt aggcttacct
    15421 tataaaaata aaaagctgtt tagtaaatat tcacttggca tgaaacagcg acttggtatt
    15481 gccaacgcta tcctgcatga cccagaactg ttagttttag atgagccaac caatggtctt
    15541 gaccctattg gtattgcgga gatgagaaag tttattaggg acttgagcgt tgagcatgga
    15601 aagacaattc ttatttccag tcatattctt tcagaaatct cattgttggc tgatgatatt
    15661 ggaattatcg accacggtgt tcttttggaa gaaagtagta tgagtgaact agaaaagaaa
    15721 aacagtaaat atatcctgct acaagtttca gatattccga agacatcact tattttagag
    15781 cgtcaattta acacgaagga ttattccgtt caagatgact acacgttaca cctttataac
    15841 actaatctgg atatgggtga aatcaataaa gcacttgtaa tgcagaatgt aattgttatt
    15901 agttctcaac tttgtaatga tactttagag gactacttta aaaaaatcac aggaggagag
    15961 ggcattgctt aaacttattc aaacagaatt tcttaaactg cgtcgtagga aacttatttg
    16021 gctgatgttg ttgtctgctc tcattatgcc gtttttcgca ctactatact tcaattattt
    16081 tggtaaaaca ggtgttgagc caacaaagtt ttataaatgg tctgcatttg gttatacact
    16141 ttggattatt ttgcccgttg ttttgggtat attttgcacc atgcttatac acgaagaaaa
    16201 ccagtatgat atgctcaaac agctttggat tgtacctatt agtaaaatgg gatacttttt
    16261 tagtaaattt ttcgttgttt tgatttactc tatttgtttt atgctgatta cagccgttgc
    16321 ttctgtgtta tttagtgtac tttctggata tgtcgtattt agctgggcaa gcattttata
    16381 tttgttgaaa aaatgtctag aaattggtgt aatcactgct tttgtaatgt tgccgatttt
    16441 ggcaatcgct acatctcaaa aaggatacat tctcccaatt tgtatcacat tggtatatgc
    16501 cttttccggt tttgttataa tgacaataaa tatgtattta caccctttat ccagtatggg
    16561 agttattatc atgagaaata aagacattcc aggtcttata ttttcacagg aaattaatgt
    16621 cccattagca tttctttgta tttgtatttg gagtattgta tcagtattgt ttgcaaacat
    16681 tgcactagga agaagaaagt gaggtgtaga taatgtggaa attactttgg gctgaatgtc
    16741 aaaaaattcg tcgttcaaaa attgtttgga ttacagtttt tgcatccatt atgatagcag
    16801 tcatagtttt tgcaggaggg caggatgtat ataatgaccc agatttacat tatggcttaa
    16861 agagcgttta tgacggttca cggtatatag acaatgcagg ttggtatata gacgcagtac
    16921 aaccttggtc aacttttttt gttcttcctg ctgtcattgc cttattagga agctatatta
    16981 tttgtcgtga agaagaggag gacactatta aatccctgcg tcttattccc ataaatgaaa
    17041 caaatttaac catagcaaaa atgattatta cttttatatt cagtatactt ctttatttgt
    17101 tactctttac tataacattt ttgactgaat ccgttttaca tttttccgat ttatcgacaa
    17161 aactggtttt aagttgcatg aaagagtatt ttcttgatgg cataggtgta ttctttgcaa
    17221 tttctcccat tattgccttg gtatcgcgca tgaaaaaagg atattggctt gcattagtat
    17281 tcacagaagt ttattctatt gctggactat ttgcgggtat gtcaaatgtc ttacaaacct
    17341 tttttcctat tgcggcaata tttaatattt ctggatacta tataactact ggagaaaaaa
    17401 ttatggggag tatcataagt ttattacttt gtgcctgcct ttctgcattt atactgaaag
    17461 ggctaaaaca caatgaaaaa aattgaaata tgtatatcaa aatgaaaaag ataaaaaaac
    17521 tgattattct aattgtattc ttgtttcttt ttggcatgtt acactgttat actgaatgga
    17581 aattcaacaa tgacccacct aaaggggtaa tagaaagaat aaatgagtgg actgataaga
    17641 ttggactgga ttagtaactt atgttaatta tagtgaatgt aatattagca agttattgtt
    17701 tcgtatttta atactataac tttaaatatt tggttttaat cttccaaacg aatataaaaa
    17761 aactgtcaca gaggcaacat atttttgaat atttataaag tggtagtttt gattttcaaa
    17821 gctgccgcct tttcttctat ataagcaaac ttatcctcaa caaagtgtaa aacatggtac
    17881 attttaagaa aaaagtacca cagacacaag caataaaaga aacgccgaga acctacaaaa
    17941 acgtagtgct tatgcagatt tacgacgcct tctattttct caaccgtctt aatgaccttg
    18001 tacaaaagaa atttttctaa tattttttat aatcttatct tgtgatgttt tttatgtata
    18061 aatgacttaa taacaaatcc aataaaaatt atggatattg gtataattag aacgaggaat
    18121 ttataatcat tataatgtga cattattctt acccaactct cagaaaaaat atatcctata
    18181 ctgattaatg aagtattcca tatggttatt cccacgatag atgatattgc aaaagttata
    18241 atattttgac ctgctatacc tgctataaaa gatatgtatg ttctacataa agggattaat
    18301 ctacatacac aaacagaaat agaagagtat ttattaaaat aatcttgaga tgcaaatatt
    18361 cctttctttg cctttggaca tatctctatt attttattta tgatagattt acctccccaa
    18421 tttcccactg tataacaaaa tatcgaacca agtatacctg caattatact taaaattaaa
    18481 attgtcagaa atccaaaatg atttcttgca gcaattgctc cacataaagg taaaacaact
    18541 tcgctaggta atggaaaaca agcatactca atcataatta atacaaatac agagattaat
    18601 ccatattgta aaataaaact attgattaca gacacttact tatctatctc ctttcttatt
    18661 taaaggtttt aagggtacat attctaagga ttctcaccct atatttaaag aatcaatctc
    18721 tttaaactat tatatgtatt tacacaaagc atttataaca tactttaaaa atagtacctt
    18781 aaaataagaa acttaataaa taaaaaaa
//
LOCUS       DAMJXI010000067        18703 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.070, whole genome shotgun sequence.
ACCESSION   DAMJXI010000067 DAMJXI010000000
VERSION     DAMJXI010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18703
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.070"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(<1..605)
                     /gene="yqeC"
                     /locus_tag="PC465_002996"
     CDS             complement(<1..605)
                     /gene="yqeC"
                     /locus_tag="PC465_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HDF2650280.1"
                     /translation="MELSNIIEKNEIITVVGAGGKTSLINYFANFYRDKLKVLLTTTT
                     KIYVPNDYDNIIITIDGTVIPSICHGITVCGSYINNENKLVSIDSSILDEIVDQFDLV
                     LIEGDGSKRKKLKGWNAKEPVVYHKTTKTIGILDITSFGMNINEENIHRVEIFKKIAN
                     LDTSSINSSSTVSIENLKNIVLNPNGLFKNYSGKRVLFINKV"
     gene            complement(788..2065)
                     /locus_tag="PC465_002997"
     CDS             complement(788..2065)
                     /locus_tag="PC465_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2650281.1"
                     /translation="MSNRIKNIHYGTQRQQLKNLTKKEYQALREMCFLAKNLYNVGTY
                     NVRQHYFNQGEHLNYEANYHVCKENENYKLLNSNIAQQILKEVDSSFRSFFGLIKLAK
                     EGKYDFRGIKSPKYLDKEGFFSIIIGQIRIKEDGILNVPMSPAFKKLYGKVSIKVPQN
                     ILEKKIKEIRIIPKHKARFFEIQYCYEIPKSEEVSNQKNALAIDLGLENLCTCVTNLG
                     DSFIIDGKRLKSVNQWANKQNDKIEALKLKKNITAITRKQFKVWNKRNNQVKDYVNKT
                     CFYIIDYCVKNNIGNLIVGYNAKLEKSDNMERKIYRNFIRIPFGEIKGKLEYLCKIKN
                     INFIRQEESYTSKSDFFADDFLPDINVDNVKKYDFKGERITRGQYKSSVGIIINADVN
                     ASLNILKKSQVVNLSNLQNNPQILKQPQRVRIS"
     gene            complement(2204..4510)
                     /locus_tag="PC465_002998"
     CDS             complement(2204..4510)
                     /locus_tag="PC465_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2650282.1"
                     /translation="MINKGIRKIDSTAIVTGKPLYTEDLIMHKDVLTLKLLRSPHAHA
                     KIKNIDTSKAEKIPGVVGIYTYKDVPQVRYCVPGQTEPEASPYDRVLLEDTVRFIGDE
                     VALVAAEDEKTALKALKMIKVDYEVLKPVFDAREAEGNEVVIHPEKDIVEPYPFGLDA
                     KNNIVSKEFFEFGDVEAKLKESDFVVESSYKTQSQSHCMMETHRSYSYKDINDRIVVV
                     SSLQSPHNVKRILRKVLGIPSSKIRVIKPRIGGGFGGKNIAATDIFTAFVTMKTGRPA
                     KFVFTRSETFVGSNSRHEMFFDVKVGADKEGNLKAIELKSLNNTGAYGGNGVSVSSES
                     GHNTLPIYNDIDAVRFNARTVYTNRLPAGALRGYGATQGIFAIDSAIDELAHKIGMDP
                     LEFRIKNIIDRYTNGKAAEDEILSCELRQCIEKGKKLINWDDKYPCKDIGNNKVRAVG
                     MAVANHGSGIPRVDMATVTIRMDEDGTYKLLSGLADLGQGADTIQAQIAAEALNTTVD
                     RISIYTGDSDLCPYDTGAFASCTTTVTGNATIKTANKLKDILLSVAESKLGFKKEDLE
                     LGKDRVFVKNDNSKFVLLEELGRESVGGIGFASDDVPVVLEATESFGMLKKIKPFIAG
                     FAEIELDKNTGEYKVINFACVPDCGTVINPTLARIQVEGGVMMGIGFAMYEDPIFDKD
                     GRLLTDSFLQYKVPTKKEVGNILVDFAENFDPGGPYGAKSLGEIVIHTPAPAIANAIF
                     NATGVRLRELPMTFEKVYMGMKNNNKQL"
     gene            complement(4503..5297)
                     /locus_tag="PC465_002999"
     CDS             complement(4503..5297)
                     /locus_tag="PC465_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HDF2650283.1"
                     /translation="MVTIKEYSVPQSLEEAYKILISKKNNVILGGCGFIKLSNKNIGT
                     AIDLKDINLNYIKEDKKNILIGADTSLRSLEIDKTIKNYCSGILSSAVSNIVGVQFRQ
                     GARIGASVFSKYGFSDLIPALLVVGAKVRLYNKGILELSEFLDSELSRDILVEVILPK
                     KDAIAVFDSIRKCTGDFSVLNSAMLKENDTYKIAIGARPQKARLALEASNILNKEKDI
                     DKASIVASKELTYGSNMRASKEYRKDMASALVKRMYNAIEEGMYND"
     gene            complement(5404..6762)
                     /locus_tag="PC465_003000"
     CDS             complement(5404..6762)
                     /locus_tag="PC465_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HDF2650284.1"
                     /translation="MKAKSTSKFELDGIPPLKEAIPLGLQHLMAMVIGSCLPAILIAN
                     AAGLNHKMSTLLIQAALVFAGLSTLLQLYPIPLFKGFKLGGGIPVIMGATAMFIGAGV
                     SVASKYGLPVLFGSQIIAGIVIIIIGFGLKKIRFIFTPAVSGTIVACMGLGLFPIAIK
                     NLAGGMGNETFGNPINFIVGISVSLMILGLNKYGKGLFKDASILVSIIFGYILSLILG
                     IVNFSSIQEFTLVALPKPLAFGLDIRLEVVVMFSIIYLVEIADIMGACTLSAVGGLNR
                     QVTDEELSSAVLGNGVLSTIGALFSATPMGMFGQNSAIVSNTKVVSKFVLAIGGIGLF
                     LAGISPLLANLIRTIPPCVVGGATLVIFSTLTTSGLRLVSMDGFNQENSMILGLSMAS
                     GIGFMVAPQVLEKFPKFIETLLADSSVVSGAMVAIIIQALYMVKFPGNKSDKVEDKNK
                     SL"
     gene            complement(8110..9159)
                     /locus_tag="PC465_003001"
     CDS             complement(8110..9159)
                     /locus_tag="PC465_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650285.1"
                     /translation="MVMQVQEKILELLYTINEDVVSIKNDMSEVKQEINVLKEDMSEV
                     KQEMTVMKEDMSEVKQEINVLKEDMSEMKQEMTVMKEDMSEVKQEINVLKGDMSEVKQ
                     EMIVMKEDMSEVRQEINIMKEDMSEVRQEINTMKEDMSEVRQEMTVMKEDMSEVKQEI
                     NVLKEDMSEVRQEINIMKEDMSEVRQEMTVMKEDTSEVKQEINVMKKDMSEVRQEITV
                     MKEDVSEVKSEVNFMQNKINNINEDMNGIKDEVSIANEKLYGIEIKIDSLECEDKSMK
                     EIQIEQNNILGSLLHNSEINKATHDNIEHNIAYIKGDTNSIKEDIAEIRRDLNLVELA
                     TSKNWSDIVKLKSVK"
     gene            complement(9389..10474)
                     /locus_tag="PC465_003002"
     CDS             complement(9389..10474)
                     /locus_tag="PC465_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HDF2650286.1"
                     /translation="MYNFLGKELKSPLIIGSGPLTYSAAGCKILSDAGAGAVVTKTIR
                     KERAINPAPHMVRNTANALLNNEKWTDFEPEQWIDFEIPQMKRDGTVCIASIGHTIEE
                     SSELVEKVANAGADFIELVSYDYRDLIPMLKDAKERVNIPVIVKLPPMIDEIGDFAKK
                     LEEAGADAITACDSVGPAFRIDIETGQPLLGGNGIGYLSGETIKPITLQRIYEIKKQV
                     NIPIIGLGGCVSGDDALEMIMAGADFVGICSVVILKGAQVISKIHDDLKSNLNRLGYN
                     TIENACGIVHNHMGDVNERLSFEFTYDEEKCTKCKMCERVCAYQARKLNDKMELNEEE
                     CRYCGLCISVCKPKALGRKISCSELNV"
     gene            complement(10510..11823)
                     /locus_tag="PC465_003003"
     CDS             complement(10510..11823)
                     /locus_tag="PC465_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2650287.1"
                     /translation="MIAIKSKYLISSADEIYTNSAVVVENDIIKDILPNEEVEIKYKN
                     IEEIIDKSDAIIMPGFVNGHMHQYGVLSRGIPANVHFTDFEGFLNDYWWPFIENRIGL
                     KEVKATTKASAIELIESGVVAFCDTLEAPNTEEGTLIEQGKILEEIGMKAILSLESCE
                     RISFENGLRCLDENSNLIKWSRENSKLINGIMCTHTSFTCSDRFIKKAKEDAKKLNAP
                     MQFHLCESIYEPNYAEKHFGKKAVDYYNDLDILDETVLASQCVKVNDEEIDILKEKGV
                     KVVHMPLSNCEVGGGFSPVPKMIKKGIKVALGTDGYINDFFEVMRGAFLMHKSVEEDA
                     SVMPANLVFRMATEHGAYVLGLQNSGKIAVGNKADIIVMEDEFKTPVTLDNIFDQIVV
                     QGKKEFISNVYIDGRHILKEKQLVDLDKKAIVKEMKEVACEFWKF"
     gene            complement(11824..14115)
                     /locus_tag="PC465_003004"
     CDS             complement(11824..14115)
                     /locus_tag="PC465_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2650288.1"
                     /translation="MVNKEVRKIDSEAIVTGKPIYTEDLIFHKDVLTIKLLRSPHAFA
                     KIKNIDIKNALKVKGVVNIFTYKDVPNYRYSMVGESYPEASPHDQLILEDVVRYVGDE
                     VAIIAAEDERAAIKAMKLIKVEYEVMTPILDARESEGNKILIHEEDDLFCPFDFGLDA
                     TKNIVSREKMGKGDVEKEFKESDVIVEHSYMTQSQAHCMMETHRAYTYIDTNGRLVVT
                     SANQSAYHMRRQVSKALGIPLSKVRVIKPRIGGGFGGKNIAVTEIYASFVTWMTKRPA
                     KLIYTREETFAMTNTRHQMFFDIKIGADKEGNIKAIDMKALNNTGAYGDNGPSVCSES
                     GHNVLPTYNNVPAIKFDGRTVYTNLVPGGALRGYGATQGTFALDCAIDELAHKLNMDP
                     TEIKLKNIIKKQTEGGIMNFPIRSCALDECIIRGKKLIGWDEKYPVRDIGNNKVRAVG
                     MSVGTHGSGIANIDMAIVNMRMDEDGTYKLFSGSSDLGTGSDTILAQIAAKALNTSID
                     RISVYTGDTDMCPYDTGAYASCTTYVTGNATIKSAESLKQKILKVAQKKLDLPIDDLI
                     LYEDRVCYSEDVEKFVLLSELGKESVGGGNQEVLYSSESYGIQESAKPFLAGFAEIEL
                     DKTTGEFKVINYACSTDCGTVMNPALARIQVEGGVTQGIGLAMYEDPRHGSDGKLQTS
                     NLLQYKVPTKKDIGNIIVDFVDNYEPTGPYGAKSLGEIVIHTPAPAIANAIYNATGVR
                     IRELPITSEKVYMAMKKLNQGGK"
     gene            complement(14105..14899)
                     /locus_tag="PC465_003005"
     CDS             complement(14105..14899)
                     /locus_tag="PC465_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HDF2650289.1"
                     /translation="MITIKEYVVPKSLDEAYELLISRKNNIILGGCGFLKLGSKNIGS
                     AIDLKDLALDYINETDDSILIGADTSLRTLELNKVIKNYCNGVISNAVSNIVGVQFRS
                     GARVGASVFAKYGFSDLIPSLLVVDAKVKLYKKGVMNLADFLESELEKDILIEVILPK
                     KDAIGVFDSIRKCTGDFAVLNGAMLKEGSIYKIAIGARPRRAKIAYKASEILSLENDI
                     EKAGEVSSEELSFGSNIRGSKEYRKDMAKALVVRMYNSIGGECDGK"
     gene            complement(14938..15384)
                     /locus_tag="PC465_003006"
     CDS             complement(14938..15384)
                     /locus_tag="PC465_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HDF2650290.1"
                     /translation="MIIKCTINNKEKELSIRPDDFLADTLRENGYVSVKKGCDTGSCG
                     LCTVMVNDKAVLSCNYLTARVDGQHITTLEGVLDEAKKFGDFLADEGADQCGFCAPGF
                     IMMVLAMKRELQNPTEEEVIDYVNGNLCRCTGYKGQLRAIHKYLNT"
     gene            complement(15456..16862)
                     /locus_tag="PC465_003007"
     CDS             complement(15456..16862)
                     /locus_tag="PC465_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2650291.1"
                     /translation="MMDILIKNAIIVTVNKEREVIFDGALVVKDNKIADIGNSKEIES
                     KYTDVKKIIDAKGKVLFPGFINTHNHLFQTLLKGLGDDMVLKDWLETMTFPAANYLEP
                     KDTYDAAMLGCIEGLRSGITTMVDYMYPHSKPGLCDGIIDAYKELGIRGILGRGCMNT
                     GAQFGVHPGIMQDVETVEKDVRRLFEKHHNTENGRIKIGVAPAAIWSNSQEMLEMLWR
                     VVKEYDDALFTVHISETPFDREAAKELHGQYDIDVLEKLGILGPNVLMVHCVYLTEKD
                     MELTKKYDMKVSHNTASNMYLSSGVAPVPEMLKKGITVSLGVDGAASNNSQDMLELMK
                     LTALQHKVNKCDPLAMSAEKVLELATIDGARAIGMEDEIGSLEIGKKADLLIFNPMLS
                     PKAIPMHNPVSTLVYSSSMKNIESVIVDGNIIMEDSKILTANEEKALKDAQDTAERLC
                     VRGTIKNRMEGHKWNSLY"
     gene            complement(16880..18250)
                     /gene="hydA"
                     /locus_tag="PC465_003008"
     CDS             complement(16880..18250)
                     /gene="hydA"
                     /locus_tag="PC465_003008"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HDF2650292.1"
                     /translation="MGTILRGGTIITSDKTYISDLRIEDEKIVEIGNNLEINGDKVID
                     ATGKIVIPGGIDTHTHFDMNAGSITTADNFETGTRAAIAGGTTTILDFAEANEGENLL
                     QGVEAYHKKASGNCYCDYGFHMTITCLNKDTFNHMEKLISDGIVSFKMYMAYDGMKVD
                     DGTIYRVLKKARDLGCIVGFHCENGDLLDVLIEENIQNGNLEPKYHPLTRPNIVEKES
                     VSRLADITKLSNSKSYVVHLSCRESLETVKMAREKNIDMIVETCPQYLLLEDNLYNKD
                     KFEGAKYVMSPPLRKKEDINYLWEGLSSGDIQTVGTDHCSFNFKGQKDLGIDDFSKIP
                     NGAPGVEHRLALLYTYGVLENRISVNKFVEVTSTNAAKIFGMYPKKGEIAVGSDADIV
                     ILNINKEETISYKTQKQNVDYTPYEGFKVKCKVEDVFLRGNHVVQSCNVKEHPTGQYI
                     KRKITK"
     gene            complement(18383..>18703)
                     /locus_tag="PC465_003009"
     CDS             complement(18383..>18703)
                     /locus_tag="PC465_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF2650293.1"
                     /translation="VEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDS
                     EITQYSFCTNGSHYAGEAGIKTIGFGPSKENLAHTIDEYIEQEQLFVGTEGYYGILKS
                     VYGK"
BASE COUNT         5610 a         3646 c         1986 g         7461 t
ORIGIN      
        1 actttattaa taaataatac tctttttcca gaataatttt taaataatcc atttggattt
       61 aatactatat tttttaagtt ttcaatactt actgtagaac tactattaat actacttgta
      121 tctaaatttg ctattttttt aaatatttct actctatgta tattctcttc attaatattc
      181 attccaaatg atgttatatc taatatccct atggtttttg tagttttatg atatactact
      241 ggttctttag cattccaacc tttaagtttt tttctctttg agccatctcc ctctattaaa
      301 actaaatcaa attggtctac aatttcatcc aaaatagagg aatcaatact tactaattta
      361 ttttcattat ttatataact gccacagact gttattccat gacaaataga tggaataaca
      421 gttccatcta ttgtaataat tatattgtca taatcgtttg gtacatatat tttagttgtt
      481 gttgtaagga gaactttcaa tttatctcta taaaaatttg caaaatagtt tataagcgaa
      541 gtttttcctc ctgctccaac tacagttatt atttcattct tttctattat atttgatagt
      601 tccacacttt cacctcttat aaccagtttt ctaatctctt aattattata gttagacctt
      661 tttagtaaaa gtgatttttg aaattccata aactcgaaag taaatagatt ctgttgtaaa
      721 caacaaggcg gatccaattc gccgctaagc tgtaagctta cgctatcagt ttatctttta
      781 aatataatta agatattctt actctctgtg gttgctttaa tatttgagga ttattctgta
      841 aattagataa attaactact tgtgattttt ttagtatatt aagactcgca tttacatctg
      901 catttataat gattccaaca ctggatttgt actgtccacg cgttattctt tcccctttaa
      961 agtcatattt tttaacattg tccacattga tatcaggtag aaaatcatca gcaaaaaaat
     1021 ctgatttact agtatagctt tcttcttgcc taataaaatt gatatttttt attttacaca
     1081 gatattctaa ttttcctttt atctctccaa atgggattct tataaaattt ctatatattt
     1141 ttctctccat attatcactt ttttctaact tagcattata tcctacaatt aaatttccaa
     1201 tattattttt tacacaataa tcaattatat aaaaacaggt tttatttaca tagtctttaa
     1261 cttgattatt tctcttattc caaactttaa attgttttct tgttattgca gttatattct
     1321 tttttaattt taaggcttct attttatcat tctgtttgtt tgcccactga ttcacagatt
     1381 ttagcctttt tccatctatg ataaaactat cacctaaatt ggtaacacat gtacataaat
     1441 tttctaaacc caagtctata gctagtgcat ttttttgatt tgaaacttcc tctgattttg
     1501 gtatttcata acaatactga atttcaaaga acctagcttt atgtttaggt attattctta
     1561 tttctttaat ttttttctct agtatatttt gtggaacttt tatacttact ttcccatata
     1621 gttttttaaa tgctggagac ataggtacat ttaaaatccc atcttctttg attcttattt
     1681 gacctattat tatgctaaaa aatccttctt tatctaaata tttaggtgat tttatccctc
     1741 taaagtcata ttttccttct ttggctaatt taattaatcc aaaaaatgac ctaaacgaac
     1801 tgtctacttc ttttaatatt tgttgcgcta tattactatt gagaagctta tagttctcat
     1861 tttctttgca tacatgataa ttagcttcat agttaagatg ttctccttga ttgaaataat
     1921 gctgtcttac attatatgta ccaacattat ataagttctt agctaagaag cacatttctc
     1981 gtagagcttg atattctttt ttagttaagt tttttaattg ttgtctctga gttccatagt
     2041 gtatattttt tattctgttt gacatgaact cacctccttt agaatatact ctactagaca
     2101 ttatatacgg tatttttaca aaacaccata tataatgtcc atttaattac tttattttac
     2161 aaaataattt aaatttactt gcttttatac atcttattat ttattataat tgtttattat
     2221 tatttttcat acccatataa actttttcaa aagtcatagg aagctctctt aaacgaactc
     2281 ctgtagcatt aaatattgca tttgctatag ctggtgctgg tgtatgtata actatttctc
     2341 ctaatgattt agcaccataa ggacctcctg ggtcgaaatt ctcagcaaaa tctaccaata
     2401 tatttccaac ttcttttttt gtaggaactt tatactgtag gaaactatct gttaataatc
     2461 taccatcttt atcaaatata gggtcttcat acattgcaaa ccctataccc atcatcacac
     2521 caccttctac ttgtattcta gctaaagttg gatttataac tgttccacaa tcaggtacac
     2581 atgcaaaatt tatgacttta tattcgcctg tatttttatc taattctatc tctgcaaatc
     2641 ctgctataaa tggttttatt tttttcaaca tgccaaaaga ttctgttgct tccaaaacta
     2701 ctggtacatc atcactagca aatcctattc ctccaacaga ttctctaccc aattcctcta
     2761 atagaacaaa cttgctatta tcgtttttaa caaaaaccct gtcttttccc aactctaaat
     2821 cttctttttt aaatcctagc tttgactctg caactgaaag taatatatct tttaatttat
     2881 ttgctgtctt tattgttgca tttcctgtaa ccgttgtcgt acaagaagca aatgctcctg
     2941 tatcataggg acataagtct gaatcacctg tataaataga aattctatct acagtagtat
     3001 ttaaagcttc cgcagcaatt tgagcttgaa ttgtatcagc cccttgacct aagtcagcaa
     3061 gaccagataa tagtttatat gtgccatctt catccattct tatagtgact gttgccatat
     3121 ctacacgcgg tataccagaa ccatgatttg ctactgccat acctactgct cttactttgt
     3181 tgtttcctat atctttacat ggatatttat catcccaatt aattaatttc ttgccctttt
     3241 ctatacattg tctcagctca caacttaata tttcgtcttc agctgctttt ccattggtat
     3301 acctatctat tatattttta attctaaatt caagtggatc cattccaatc ttatgtgcca
     3361 attcatcaat agcactatct attgcaaata ttccctgtgt agcaccatac cctctaagtg
     3421 ctcctgctgg taacctatta gtatatactg ttctagcatt aaatctaaca gcatcaatat
     3481 cattatatat tggtaaggta ttgtgtccag attcggaaga aacagagaca ccattcccac
     3541 cataagcacc tgtattgttt aatgacttta gctctattgc ttttaaattt ccttctttat
     3601 ctgcaccaac tttaacatca aaaaacattt catgtctact attagaacct acaaaagttt
     3661 cacttcttgt aaatacaaat tttgctggtc taccagtttt catagtaaca aatgcagtaa
     3721 atatatctgt tgctgctata ttctttcctc caaatccacc acctattcta ggtttaatta
     3781 ctcttatttt tgaagatggt atacccaata cttttctaag tattctcttt acattgtgtg
     3841 gtgattgtaa tgatgaaact acaacaattc tatcatttat atctttatat gaatatgacc
     3901 tatgagtttc catcatgcaa tgcgattgac tttgggtttt gtatgaagat tcaaccacaa
     3961 aatcactttc tttaagctta gcttcaacat ctccaaattc aaaaaattct tttgatacta
     4021 tattattttt tgcatccaat ccaaaagggt atggctctac tatgtctttt tctggatgta
     4081 taacaacttc atttccttct gcttctcttg catcaaacac aggctttaaa acctcataat
     4141 ctacctttat catttttaag gctttaagtg ccgttttctc atcttcagca gccactaaag
     4201 ctacttcatc tccaataaat ctaactgtat cttcaagtaa aactctatca taaggtgatg
     4261 cttctggttc tgtttgacct ggcacacaat atctgacctg tggtacatct ttatacgtat
     4321 aaatacccac aacccctgga attttttcgg cttttgatgt atctatattc tttatcttag
     4381 catgagcatg tggacttcta agtagtttta atgtcaaaac atctttatgc ataatgaggt
     4441 cttcagtata tagaggtttt cctgtgacaa ttgctgtact atctatcttt cttatcccct
     4501 tattaatcat tatacattcc ctcctcaata gcattataca tccttttaac taatgcactt
     4561 gccatatcct ttctgtactc tttactagct ctcatattac ttccataagt aagttcctta
     4621 ctagcaacaa tagatgcctt atctatatct ttttctttat ttaatatatt actcgcttca
     4681 agtgctaatc tagctttttg aggtcttgcc ccaattgcta ttttgtaagt atcattttct
     4741 tttagcattg ctgaatttaa tacagaaaaa tctcctgtgc attttcttat tgagtcaaaa
     4801 acagctattg catctttttt tggtagtatt acttcgacca atatatccct acttaattca
     4861 ctatccaaaa actcacttaa ctctagtatt cctttattgt ataatctcac cttcgctcca
     4921 acaaccaaaa gcgctggtat taagtcagaa aagccatact ttgaaaatac acttgcacca
     4981 attctagccc cttgtctaaa ttgaacacca actatattag aaacagcgct tgaaagtatt
     5041 ccactacagt aattttttat agttttatca atttctaaac ttctaagtga agtatctgca
     5101 cctatcaaaa tatttttttt atcctctttt atataattta gatttatatc ttttaaatct
     5161 atcgctgttc ctatattttt attacttaat tttataaatc cacatccacc taaaataaca
     5221 ttattttttt tagaaattaa aattttatat gcttcttcta aactctgtgg aactgaatat
     5281 tcctttatag taaccatctt atccccccat cattaactta ttaaaacaca aaagttttta
     5341 ataaatcttt tatttatatt tataattgta gtatatttaa ttcacatata ttaaaccttt
     5401 acattataaa cttttatttt tatcctcaac cttatcactt ttatttccag gaaattttac
     5461 catatataaa gcttgaatta ttatggctac cattgctcct gaaactacac ttgaatctgc
     5521 aagtaatgtc tctataaatt ttggaaattt ttcaagaact tgaggagcta ccatgaatcc
     5581 aataccagaa gccatagaaa gacctaatat catgctattt tcttgattaa atccatccat
     5641 actaacaagt cttaaaccag atgttgtaag agttgaaaat ataacgagtg ttgctcctcc
     5701 aaccacacag ggaggaattg ttcttattaa attagctaat aaaggcgata ttcctgccaa
     5761 aaataatcca attcctccaa tagctagtac aaatttactt acaacctttg tattggaaac
     5821 gattgcagaa ttttgtccaa acatccccat tggagttgca gaaaataatg cacctattgt
     5881 agagagtact ccatttccta aaacagcaga agaaagttct tcatctgtta cttgtctatt
     5941 aagccctcct accgcagaaa gtgtacaagc acccattata tcagctatct caactaaata
     6001 tattattgaa aacattacaa caacttcaag tcttatatct agcccaaaag caagtggttt
     6061 tggaagtgca accaaagtaa actcctgaat tgaagaaaaa tttactatac ccaaaattaa
     6121 tgataaaatg tatccaaaaa ttatgctaac taatattgat gcatctttaa ataatccttt
     6181 tccatactta tttaatccta atatcataag agatacagat attccaacta taaaattaat
     6241 tggattccca aaagtctcat tgcccatacc cccagctaag ttttttatag ctattggaaa
     6301 aagtccaaga cccatacatg caactattgt tcctgataca gctggagtaa atataaatcg
     6361 tattttttta agaccaaaac caattataat tattactata ccagctatta tttgagagcc
     6421 aaataatact ggtagtccat acttacttgc aacagatacc ccagctccta taaacatagc
     6481 tgtagctccc attataactg gtattcctcc tcctaattta aaacctttaa acaaaggtat
     6541 tggatataat tgtaataaag ttgataatcc tgcaaaaact aatgcggctt gaatcaataa
     6601 tgttgacatc ttatgattaa gtccagctgc atttgcaatc aatatcgctg gtaaacaact
     6661 acctattacc attgccatta agtgttgtaa ccctaaaggt attgcttcct ttagtggtgg
     6721 tattccgtct aattcaaatt ttgatgtact ttttgctttc ataataaaaa ctcccgttac
     6781 ataaaactta ttgaattata taaatactta aaaatctaat atattaaatt aatgatgttc
     6841 ataaatatca actatactcc aacatatatt taagttttta gtcttaaaaa acagatgcaa
     6901 taaatttaat tattaacaaa taaacgtatt ctttaatttt gtatacatta tataccatgc
     6961 tttacaaata taagagtatt atagctatga atttttaatt ttttatagta aatttaattc
     7021 aatttaaatc tttcaatctt aatcattata agttataagt tttcataagt atttacatgt
     7081 ttcaagtttt aaacatttac ctataaacgc tactttatag atgtcacttc aaatccagtg
     7141 acctcatact ttcatatgag cgtagactat ttcttcatct tcagcattac ctgctaagag
     7201 caacccgttt ccactatcaa tcgcttatag tgtactctct ctcgagatag tcgtttgacc
     7261 ttcctatttc taggcttggc gaccaaatgt ccatttttaa gtacttaggc tctcaccata
     7321 taccatcctc actattgttt ctggttttca ccacattcat aaaagtttct ttctatcttt
     7381 tattgtagtt gcaaggcttt aggatttact ggttttaaag ttgtgtccta catagatttc
     7441 tctatgtacg gggccaaaag tacaatttat ttaacatact ttgctttacc ccctgtaaat
     7501 aatattattt actctttcac tgtttttgtt attaaattaa ttaaatatca attaatctaa
     7561 gcataaaata attatttaat ttaaactcaa aatatttatg aatattttat aatataattc
     7621 tcataagaca gaaaaactta ataagctatg tatctcagtt gtaccaatgt actctccttt
     7681 actatatttg tatctgcaac ataaaatata caagtttcta tctatttata gatatatata
     7741 tctataagca aaatagtaat attattttta atagtaaaaa ttttattcat attactattt
     7801 ataattttta tagagcaatt ttagtgccaa tatttgcata catttgtata gtataaaatt
     7861 tttatgttct cattgataaa attttactta tttcaagcgt tctattagat tttatcatct
     7921 aaattttagg ttttattttt ataaattaat tgtatttaca taaaaaaaaa gacctaaaaa
     7981 caaattttta acggtctttt ctcaattttt tattttcatt tctaaaattt ataataaata
     8041 gtaagaacac tataaattct tttatataaa attcttagtt tgtggatgat aaattagtga
     8101 attaaaatac tactttactg attttagttt gacaatatca ctccaatttt tactagtggc
     8161 taactctact aaatttaagt ctcttcttat ttcagctata tcctctttta tagaattagt
     8221 gtcacctttt atatatgcta tgttatgttc tatattatca tgagtagctt tatttatttc
     8281 agaattatgt aataaacttc ctaaaatatt attctgttct atctgtatct ctttcattga
     8341 tttatcttca cattctagac tatcaatctt aatttcaatt ccatataatt tttcatttgc
     8401 tatggatacc tcgtccttaa ttccattcat atcttcatta atgttattta ttttattttg
     8461 cataaagttt acttctgatt taacttcgga aacatcttct ttcattacag ttatttcttg
     8521 tctcacttct gacatgtctt ttttcattac atttatctct tgttttacct ctgatgtatc
     8581 ttctttcatt acagtcattt cttgtcttac ttcggacata tcttctttca ttatatttat
     8641 ctcttgtctt acttcggaca tatcttcttt taatacattt atctcctgtt ttacttccga
     8701 catatcttct ttcattacag tcatttcttg tcttacttcc gacatatcct ctttcattgt
     8761 atttatctct tgtcttacct cggacatatc ctctttcatt atatttatct cttgtcttac
     8821 ctcggacata tcttctttca ttacaatcat ttcctgtttt acttctgaca tatctccttt
     8881 taatacattt atttcctgtt ttacttccga catatcttct ttcattacag tcatttcttg
     8941 tttcatttcc gacatatctt cttttaatac atttatttcc tgttttactt ccgacatgtc
     9001 ttctttcatt acagtcattt cttgttttac ttccgacata tcttctttta acacatttat
     9061 ttcttgtttt acttccgaca tatcattttt tatgctaact acatcttcat ttatagtata
     9121 taataactct aaaatcttct cttgcacttg catcaccatc cctattaatt attataacat
     9181 tttacacaaa tgctatacaa tgttaacata tatatcagaa ttattaaaat tttaattaaa
     9241 caaaattgat tcactttatt acttcaaaac taattaatat ctaaaataac tacaaataaa
     9301 caaaaataag gtcaacaaca aaaaaggctt atctctttga gatagccttt cttattttta
     9361 tttaaaactt tgttttttat aaaataatct atacattcag ctctgaacat gaaatttttc
     9421 ttccaagtgc ttttggttta caaactgata tacaaagtcc acaatatcta cactcttctt
     9481 cattcaattc catcttatca ttcaattttc tcgcttgata tgcacaaact ctctcgcaca
     9541 tcttacattt agtacatttt tcttcatcat aagtaaactc aaagctaagt ctttcattaa
     9601 catctcccat atgattatgt actataccac aagcattttc tatagtatta tatcctaatc
     9661 tattaagatt agattttaaa tcatcatgta ttttagatat tacttgtgca ccttttaaaa
     9721 ttactactga acatatacca acaaagtcag cacctgccat aatcatttct aaggcatcat
     9781 ctccacttac acatccacct aagccaatta ttggtatatt aacttgtttt tttatttcat
     9841 atattctctg taaagttatt ggcttgatag tttctccact taaatatcct attccatttc
     9901 cacctaataa aggttgccct gtttctatgt ctattctaaa tgctggtcct acagagtcac
     9961 aagcagttat tgcatctgct cctgcttctt ctaatttttt agcaaaatcg cctatctcat
    10021 ctatcatagg aggaagttta actattacag gtatatttac tctttccttt gcatctttaa
    10081 gcattggtat caaatctcta tagtcataag atactaattc aataaagtca gctcctgcat
    10141 ttgcaacttt ctctactaat tcgctacttt cttcaattgt atgacctatt gaagctatac
    10201 agacagtccc atctcttttc atttgtggta tttcaaaatc tatccattgc tctggctcaa
    10261 aatctgtcca tttttcatta tttaaaagag cattagctgt atttctaacc atatgtggtg
    10321 ctggatttat agctctttct tttcttatag tcttagtcac aactgcccct gctcctgcat
    10381 cacttaatat cttgcatcca gctgcactat atgttaatgg tcctgaacct attataagtg
    10441 gtgattttaa ttctttacct aaaaaattat acattatctg cttccccttt tcatatatat
    10501 ttacattcgt taaaatttcc aaaattcaca agcaacttct ttcatttctt taacaatagc
    10561 ttttttatct aaatcaacta actgtttttc ttttaaaata tgtctaccat ctatgtatac
    10621 atttgatata aattcttttt taccctgaac tactatctgg tcaaatatat tatcaagagt
    10681 cacaggagtt ttaaattcat cttccataac tattatatca gccttattac caactgctat
    10741 tttaccagaa ttttgaagtc ctaatacata agcaccatgc tctgttgcca ttctaaatac
    10801 taaatttgct ggcattactg atgcatcttc ttcaactgat ttatgcatta aaaatgcacc
    10861 tctcataact tcaaaaaaat catttatata tccatcagta cccagtgcca cttttatgcc
    10921 ttttttaatc atttttggta ctggagaaaa acctccacct acttcacagt tactaagagg
    10981 catatgaacc acttttacgc ctttttcttt taatatatct atttcttcat catttacttt
    11041 tacacactga gatgctaata cagtttcatc caatatatct aaatcattat agtagtcaac
    11101 tgcttttttg ccaaagtgtt tttcagcata gtttggctca tatatactct cacataaatg
    11161 aaattgcatt ggtgcattta atttttttgc atcttcttta gctttcttaa taaatctatc
    11221 agaacatgtg aagcttgtat gtgtacacat tattccattt attaatttac tattttctct
    11281 actccacttt attaaattag aattttcatc taaacatcta agtccatttt caaagcttat
    11341 tctttcacaa ctttctaagg ataaaatcgc tttcatgcct atttcttcta gtatttttcc
    11401 ttgctcaatt aaagttcctt cttctgtatt tggagcttct agggtatcac aaaaagctac
    11461 cacaccagat tctataagtt ctattgctga tgctttagtt gttgccttca cttcttttaa
    11521 tccaattcta ttttctataa atggccacca atagtcattt aaaaaacctt caaagtcagt
    11581 aaaatgtaca tttgccggta ttcccctaga aagaactcca tattgatgca tatgaccatt
    11641 gacgaatcct ggcattatta tagcatctga tttatctatt atttcttcaa tatttttata
    11701 ttttatttca acttcttcat ttggcaatat atcttttata atgtcatttt ctactacaac
    11761 agcagaattt gtatatattt catcagcaga agatattaag tatttacttt taatagcaat
    11821 catttattta cctccctgat ttaatttttt catggccata taaactttct cagaagttat
    11881 aggaagttct cttatacgaa ctcctgtggc attgtatatt gcatttgcta ttgctggtgc
    11941 aggtgtatga ataactatct ctcctaaaga tttagctcca tatggacctg ttggctcata
    12001 attatctaca aaatcaacaa ttatgtttcc tatatctttt tttgttggaa ctttgtattg
    12061 taatagatta gaagtttgaa gctttccatc agaaccatgt ctagggtctt catacattgc
    12121 aagccctata ccttgagtta caccaccttc aacttgtatt ctagcaagtg caggattcat
    12181 aacggtacca caatctgtag aacaagcata atttattact ttaaactccc ctgttgtttt
    12241 atctaactct atttcagcaa atcctgctaa gaatggttta gcactctctt gtataccata
    12301 agattcagat gaatataaaa cttcttgatt tccaccacca acagattctt ttcctaattc
    12361 acttaacaaa acaaacttct ctacatcttc actataacaa actctgtctt catatagtat
    12421 taaatcatct attggtaaat cgagtttctt ctgtgctact tttaatatct tttgttttaa
    12481 actttcagca gattttattg tagcatttcc agttacataa gtagtacaag aagcgtatgc
    12541 accagtatca tatggacaca tatctgtatc tcctgtataa acggaaattc tatcaataga
    12601 tgtattcaat gcttttgcag ctatttgtgc aagtattgtg tcagaaccag ttcctaagtc
    12661 tgaagaccca gaaaacaact tataagttcc atcttcatcc atcctcatat ttactattgc
    12721 catgtctatg ttggctatac cagaaccatg agttcccaca gacattccaa cagccctcac
    12781 cttattgttg ccaatatccc taacagggta cttttcatcc catccaataa gttttttacc
    12841 tctaattata cattcatcaa gtgcacaact tcttattgga aaattcatta ttccgccttc
    12901 agtttgtttt tttataatat tctttaactt tatttctgtt gggtccatat taagtttatg
    12961 cgctaattca tcaattgcac aatcaagtgc aaatgtacct tgtgttgctc catatcctct
    13021 taatgctcct cctggaacta aattagtata tacagttctc ccatcaaatt ttattgcagg
    13081 tacattatta tatgttggaa gtacattatg acctgattca gagcaaactg aaggtccatt
    13141 atcaccataa gcgcctgtat tgttcaatgc tttcatatct atagctttta tgtttccttc
    13201 tttatctgcc ccaattttta tatcaaaaaa catctgatgt ctagtattag tcattgcaaa
    13261 agtttcttct ctagtataaa ttagttttgc tggtcttttt gtcatccaag ttacaaatga
    13321 tgcatatatc tctgttacag ctatgttttt tccaccaaaa cctccaccta ttcttggttt
    13381 tattactctc acttttgaaa gaggtattcc cagtgcttta gaaacctgtc ttctcatatg
    13441 ataagctgat tggtttgcag aagttactac taatctgcca ttcgtatcta tatacgtata
    13501 agctctatga gtttccatca tacaatgggc ttgtgattga gtcatataag aatgttctac
    13561 tattacatca ctttctttaa actctttttc tacatcccct ttacccattt tttctctcga
    13621 tacaatattt tttgtagcat ccaatccaaa atcaaatgga caaaacaaat catcttcttc
    13681 atggattaaa attttatttc cttccgattc tcttgcatcc aatataggag tcattacttc
    13741 atattcaact tttataagtt tcatagcttt aatagcagcc ctttcatctt cagcggctat
    13801 tatagcaact tcatctccta catatctaac tacgtcttca agtattaatt ggtcatgagg
    13861 tgatgcttct ggatatgact ctccaaccat tgaatatcta taatttggaa catctttgta
    13921 agtgaatatg tttactacac cttttacctt taatgcattt tttatatcta tgttttttat
    13981 cttcgcaaaa gcatgtggac ttctaagaag cttaattgtt aaaacatctt tatgaaaaat
    14041 taaatcttct gtatatattg gttttccagt aacaatggct tcactatcta tttttcttac
    14101 ctctttattt accatcacac tcacctccaa tactattata cattctcact actaaggctt
    14161 ttgccatatc ttttctgtat tctttacttc ctcttatatt acttccaaat gaaagttctt
    14221 cacttgatac ttcaccagct ttttctatat cattttctaa acttaatatt tcacttgctt
    14281 tataggcaat ttttgctctt cttggtctag cgcctattgc aattttataa atacttcctt
    14341 cttttaacat tgctccattt aatactgcaa aatcacctgt acattttctt atagaatcaa
    14401 atacacctat agcatctttt ttaggtaata taacttctat taatatatct ttttcaagct
    14461 cactttctaa aaaatcagct aagttcataa cccctttttt atataactta acctttgcat
    14521 ctaccactag taatgaaggt attaaatctg aaaatccata cttagcaaat acgctagctc
    14581 ctactctagc tccacttcta aattgaactc ctactatatt agaaacagcg tttgaaatta
    14641 ccccattaca gtaattttta ataaccttat ttaattctaa agttcttaaa cttgtgtctg
    14701 ctccaattaa tatgctatca tcagtttcat ttatataatc taaagctaag tcttttaaat
    14761 ctattgctga gccaatattt ttactaccta gttttaaaaa tccacatcct ccaagtatta
    14821 tgttgttttt tcttgatatt agcagttcat aagcttcatc taaacttttt ggaactacat
    14881 attcctttat agttatcata ctctctcccc atatcaactt aattttcact taaaagtcta
    14941 agtgtttaaa tatttatgta ttgctcttaa ttgaccttta tatcctgtac atctacaaag
    15001 gttaccattt acataatcta taacttcttc ttctgttgga ttttgaagct ctcttttcat
    15061 tgccaaaacc atcattataa atccaggagc acaaaatcca cactggtcag ccccttcgtc
    15121 tgcaagaaaa tctccaaact tctttgcttc atccaagaca ccctcaagtg ttgtaatatg
    15181 ctgaccgtct actctagcag taagataatt acatgaaagc acggccttgt catttaccat
    15241 cactgtacat aacccacatg agcctgtatc acaccctttt ttaacactta catatccatt
    15301 ttctcttaat gtatctgcta aaaaatcatc tggtcttata cttaattctt tttctttatt
    15361 atttatggta catttgataa tcaaataaat cacctcaaaa ctcatatttt taagctaaag
    15421 ttttactata cttttctatg aataaattac atttattaat aaaggctatt ccatttatga
    15481 ccttccattc tattttttat agttcctctt acacaaagtc tctcagctgt atcttgagca
    15541 tcttttaatg ctttctcttc attagctgtc aatatttttg aatcttccat tattatattt
    15601 ccatctacta taacactctc tatatttttc atactagaag aatatactaa tgtagatacc
    15661 ggattatgca taggtatcgc ttttggtgaa agcattggat taaatattag taagtctgct
    15721 tttttaccta tctccaatga acctatctca tcttccattc caatagctct tgctccatct
    15781 atagttgcca actcaagaac tttttctgct gacattgcta atgggtcaca cttattaact
    15841 ttatgttgaa gtgctgttaa tttcataagt tcaagcatat cttgagagtt attactagcg
    15901 gctccatcta ctcctaaact aactgttatt ccttttttaa gcatttctgg tactggtgca
    15961 acacctgaag ataagtacat attacttgct gtattatgag acactttcat atcgtatttt
    16021 ttagtaagtt ccatatcttt ttcagttaga tacacacaat gtaccataag cacatttggt
    16081 ccaagtattc ctaatttttc taaaacatct atgtcatatt gcccatgcaa ttcttttgct
    16141 gcttctctat caaaaggagt ctctgatata tgtactgtaa ataaagcatc atcatattct
    16201 tttactactc tccatagcat ttcaagcatt tcttgagaat ttgaccatat tgctgcagga
    16261 gctactccta ttttgattct tccattttct gtattatggt gtttttcaaa caatcttctt
    16321 acatcttttt caaccgtttc tacatcttgc attattccag gatgaactcc aaattgagct
    16381 cctgtattca tacatcctct tccaagtatt cctcttattc ctaattcttt ataagcatct
    16441 attattccat cacaaagacc tggcttacta tgaggataca tgtagtcaac cattgttgtt
    16501 ataccacttc taagtccttc aatacatcca agcattgcag catcataagt atcttttggc
    16561 tctaaatagt tagctgctgg aaatgtcata gtttctaacc agtctttaag taccatatca
    16621 tctcccaatc cttttaataa agtttggaat aaatgattat gtgtatttat aaaacctggg
    16681 aataaaactt tacctttagc atctataatt tttttaacat cagtatattt actttctatc
    16741 tctttagaat ttccaatatc agcaatcttg ttatctttta ctactaatgc cccatcaaaa
    16801 ataacttctc tctctttatt cacagttact attatggcat tcttaataag tatatccatc
    16861 attcttattt ccccccgcat tatttagtaa tttttctttt aatatattga cctgttggat
    16921 gttctttaac attacaactt tgtactacat gatttcctct caaaaataca tcttcaactt
    16981 tacatttaac cttaaatcct tcatatggag tataatctac attttgtttt tgagttttat
    17041 aactaattgt ttcttcttta ttgatattta aaatgactat atctgcatca cttcctacag
    17101 ctatctcacc ttttttagga tacattccaa atatttttgc agcattcgta gaagtaactt
    17161 ccacaaactt atttacactt attctatttt ctaagacccc atatgtatat aaaagtgcta
    17221 acctatgttc aacaccaggt gctccatttg gtatcttact gaaatcatca attcccaagt
    17281 ctttttgccc cttaaaatta aatgaacagt ggtctgtgcc aactgtttga atatctccac
    17341 tagacaatcc ttcccaaagg taatttatgt cttctttttt tcttaaagga ggagacatta
    17401 catacttagc accctcaaat ttatccttat tatataaatt gtcttctaat aatagatact
    17461 gtgggcatgt ttctactatc atatctatat ttttttctct agccattttt acagtttcaa
    17521 gtgactccct acaacttaag tggactacat aggattttga attagataat ttagttatat
    17581 cagcaagtct tgaaacagac tctttctcaa ctatgttagg tcttgtaagt ggatgatatt
    17641 ttggctctaa attaccattt tgtatatttt cttctatcaa tacatctagt aaatccccat
    17701 tttcacaatg aaatccaact atacaaccta aatcccttgc tttctttaaa accctgtata
    17761 ttgttccatc atctactttc atgccatcat atgccatata catcttaaaa gatactatcc
    17821 catctgaaat aagtttttcc atatgattaa atgtatcttt atttaaacat gtaattgtca
    17881 tatgaaaacc ataatcacaa taacaatttc cacttgcttt tttatgatat gcttctacac
    17941 cttgcagtag gttttccccc tcattggctt ctgcaaaatc tagtattgta gtagttcctc
    18001 cagctatagc tgctcttgtt cctgtttcaa aattatctgc agttgtaata gaacctgcat
    18061 tcatatcaaa atgagtatgt gtgtctattc caccaggaat tacaatttta cctgtagcat
    18121 caataacctt atcaccattt atttctaagt tatttcctat ttcaactatc ttttcatctt
    18181 ctatccttaa atcacttata taagtcttat cagaggtaat tatagttcca cctcttagta
    18241 ttgttcccat atatacctcc taacttttaa gctttaaagt attttctaag tattgtaaaa
    18301 ctttatttaa aattgtattt tctaaaggtg ctatattcag cacctctaga ctatatttaa
    18361 ataatttatt gtgaactaaa tattattttc cgtatacaga ttttaatatt ccatagtaac
    18421 cttctgttcc tacaaataac tgttcttgct ctatatactc atctattgtg tgagcaagat
    18481 tttccttaga aggaccaaat cctatagttt ttattccagc ttcacctgca tagtgacttc
    18541 cattcgtaca gaatgagtat tgagttattt ctgaatctat tccagcttct tttaatccct
    18601 tatatgctgc ttgaacaaat tcatcttctt cgtcatataa ccaacctggg aagaatcttt
    18661 cactttctat agtatttcct gtatagcaat cagctttttc aac
//
LOCUS       DAMJXI010000068        18703 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.071, whole genome shotgun sequence.
ACCESSION   DAMJXI010000068 DAMJXI010000000
VERSION     DAMJXI010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18703
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.071"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            100..1701
                     /locus_tag="PC465_003010"
     CDS             100..1701
                     /locus_tag="PC465_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp11"
                     /protein_id="HDF2650294.1"
                     /translation="MKMNKKILSLGLAVSLILVNFKSVNASSVVEKIYGKDRYETAAK
                     IADKQTYETVILVNTEKSLADGLSASGLSGATKAPILFTQQNKIPADTNRCLKNIKKA
                     YIIGTEDTISKSVEKELDSKNIEVKRIGGEDRLKTSYLIAKEIATIKKVDKVLLTNAY
                     SGEADAMSVSSVATRDGAPIILTDGKSVPFDVKNIQSYCIGSEEIMSNLLVKNTNSVR
                     IEGTDRFETNKNVIDYFFNSADGFYVSDGYQLVDAIAAAPLTKNSPMVLVNDGSDKTV
                     LEGAKNITSVGEIDEKVIQQCISASKSNGQPPTITVGSTEVYKGEKFDTGKLNIVAKD
                     NTGKVLPIEVDGFIDTNRVGTYILTLKATDEWGKSTGKRVEIKVLDDKSHDYNSPEFK
                     KMVSTEMYNLINSYRKEKGKEPLVVSSRLEGMANAWSKYMMDKKVFAHYIDGKNAPQV
                     FSEFGMRSEENIAYIYIDSKNVQTTQDAKDLAKAIFEVWKKSPEYNANMLSDEFYSTG
                     FGLYILSDGQVHATQEFLNGNEDSL"
     gene            1920..3509
                     /locus_tag="PC465_003011"
     CDS             1920..3509
                     /locus_tag="PC465_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp12"
                     /protein_id="HDF2650295.1"
                     /translation="MKVNKRVLSIGLAISLIMAGAPNINALSSIEKIQGKDRYETAAK
                     IAQKQTYENVVLVNTDNTLADGLSASGLAGTVKAPILLSQRNSIPSDTEKMLKDVKKV
                     YIIGTEDSIGKSVENELKQKGIEVKRIGGNDRIETSYLIAKEIASIKPIDKVFITNGY
                     TGEADAMSASSVASRDGAPIILTNGKNVPFEKKEGVQCYALGSEEIISNDLVKKTNAV
                     RLAGEDRFETNKKVIKHFYSSAKEFYLSKGYQLVDAVAGSSIAKNAPIVLVDGNSDKS
                     VLRSADKITALGGIDEKTLEQCLSASSLDASAPTITVGNLNIYQGDKFDISKLNIVAK
                     DSNGNDLTPELIGNINTDKVGKYKVTIKATDIGGKTTSISVEVNVLEYKTNDMNSSEF
                     KRMVSSEMYNLVNSYRKEKGKEPLQVSKNLEGLSNSWSKYMADKGQFSHVIDGKKSVE
                     VFTGYGLRSEENIAFVPLVTKSTYTTKDARELANVIFTVWKKSDKYNENMLNSDFVYT
                     GFGLYILPNGEVYATQEFLNK"
     gene            3721..5991
                     /gene="slpA"
                     /locus_tag="PC465_003012"
     CDS             3721..5991
                     /gene="slpA"
                     /locus_tag="PC465_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein SlpA"
                     /protein_id="HDF2650296.1"
                     /translation="MNKKNIAIAMSGLTVLASAAPVFADDTKVETGDQGYTVVQSKYK
                     KAVEQLQKGILDGSITEIKVFFEGTLASTIKVGSELNAADASKLLFTQVDNKLDNLGD
                     GDYVDFLITSPGQGDKITTSKLVALKDLTGASADAIIAGTSSADGVVTNTGAASGSTE
                     TNSAGTKLAMSAIFDTAYTDSSETAVKITIKADMNDTKFGKAGETTYSTGLTFEDGST
                     EKIVKLGDSDIIDITKALKLTVVPGSKATVKFAEKTPSASVQPVITKLRIINAKEETI
                     DIDASSSKTAQDLAKKYVFNKTDLNTLYKVLNGDEADTNGLIEEVSGKYQVVLYPEGK
                     RVTTKSAAKASIADENSPVKLTLKSDKKKDLKDYVDDLRTYNNGYSNAIEVAGEDRIE
                     TAIALSQKYYNSDDENAIFRDSVDNVVLVGGNAIVDGLVASPLASEKKAPLLLTSKDK
                     LDSSVKAEIKRVMNIKSTTGINTSKKVYLAGGVNSISKEVENELKDMGLKVTRLAGDD
                     RYETSLKIADEVGLDNDKAFVVGGTGLADAMSIAPVASQLRNANGKMDLADGDATPIV
                     VVDGKAKTINDDVKDFLDDSQVDIIGGENSVSKDVENAIDDATGKSPDRYSGDDRQAT
                     NAKVIKESSYYQDNLNNDKKVVNFFVAKDGSTKEDQLVDALAAAPVAANFGVTLNSDG
                     KPVDKDGEVLTGSDNDKNKLVSPAPIVLATDSLSSDQSVSISKVLDKDNGENLVQVGK
                     GIATSVINKLKDLLSM"
     gene            6227..8572
                     /gene="secA"
                     /locus_tag="PC465_003013"
     CDS             6227..8572
                     /gene="secA"
                     /locus_tag="PC465_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDF2650297.1"
                     /translation="MSVLDAILDKADEQEIKKLNLIVDKIESLEKDMEIKENEQLKEM
                     TNTFRLRLDKGESLDDILPEAFAVVREVSKRVLGMRQYKVQLIGGIVIHQGKIAEMKT
                     GEGKTLVEVAPVYLNALTGKGVHVITVNDYLAERDKELMRPVYEFLGLTVGVILSNQD
                     PSIRKEQYKCDITYGTNSEFGFDYLRDNMVPDLSHKVQRELNFAIVDEIDSILIDEAR
                     TPLIIAGDGDEDLKLYELANNFVKTVKEEDFEMDRKDKTIALTASGISKAESFFGITN
                     LTDIKNIELYHHINQALRGHKLMEKDVDYVISNGEVMIVDEFTGRVMDGRRYTDGLHQ
                     AIEAKEGVEIKNESKTMATVTYQNFFRLYEKLSGMTGTAKTEEGEFESIYKLNVVQIP
                     TNRPVIRADLHDKVFKTEEEKYSAVVEEIIRIHKTRQPILVGTVSVEKSEKLSKMLKK
                     QGIKHQVLNAKQHDKEAEVISKAGKLDAITIATNMAGRGTDISLGAGDKEEEEKVKNL
                     GGLYVIGTERHESRRIDNQLRGRSGRQGDPGTSRFFVSLEDDVIKLYGGKTIEKLMKR
                     TSSKENTAIESKALTRAIERAQKGVEGKNFEIRKNVLKYDDTINEQRKVIYNERNKVL
                     NDEDIKEDIQKMVKDIIQEAGETYLIGRKRDYYGYFKHLYSTFMPADTLLIPGVDKKS
                     VQEIIDSTYEISKRVYDLKKMMIGIDKVAELEKTVLLKVVDQYWIDHIDAMEQLRQYI
                     GLKSYAQKDPFKEYALEGYDMFEALNKNIREATVQYLYKFN"
     gene            8987..10858
                     /locus_tag="PC465_003014"
     CDS             8987..10858
                     /locus_tag="PC465_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp2"
                     /protein_id="HDF2650298.1"
                     /translation="MNKKNLSVIMAAAMISTSVAPVFAAETTQVKKETITKKEATELV
                     SKVRGLMSQKYTGGSQVGQPIYEIKVGETLSKLKIITNIDELEKLVNALGENKELIVT
                     ITDKGHITNSANEVVAEATEKYENSADLSAEANSITEKAKTETNGIYKVADVKASYDS
                     AKDKLVITLRDKTETVTSKTIYVGIGDEKVDLTANPVDSTGTNLDPSAEGFRVNKIDK
                     LGVAGAKNIDDVQLAEITIKNSDLNTVSPQDLYDGYRLTVKGNMVANGTSKSISDISA
                     KDSETGKYKFTIKYTDASGKATELTVESTNEKDLKDAKAALEGNSKVKLIAGDDRYAT
                     AVAIAKQTKYTDNIVIVNSNKLVDGLAATPLAQSKKAPILLASDNEIPKVTLDYIKDI
                     IKKSPSAKIYIVGGESAVSNTAKKQLESVTKNVERLAGDDRHMTSVAVAKAMGSFKDA
                     FVVGAKGEADAMSIAAKAAELKAPIIVNGWNDLSADAIKLMDGKEIGIVGGSNNVSSQ
                     IENQLADIDKDRKVQRVEGETRHDTNAKVIETYYGKLDKLYIAKDGYGNNGMLVDALA
                     AGPLAAGKGPILLAKTDITDSQKNALSKKLNLGAEVTQIGNGVELTVIQKIAKILGW"
     gene            10965..11672
                     /locus_tag="PC465_003015"
     CDS             10965..11672
                     /locus_tag="PC465_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HDF2650299.1"
                     /translation="MVDATLFFTPHQDDETLSMGSAIIEHVEKSDTHVILCTDGSKSI
                     IRKVLDDGGSCSYHIKDVHKYSLSENEFSKDRDEEFKDSCEAMGVKESNIHIEDNRAH
                     DGELSKEKAREIILKYLEEYPDAKVKTVTPFKASGIHEDHRALGEAALELYKEGKIKD
                     LRFYVEPYDYKDFKKVNPNVEVWKVLPSQEEKLLSAMNAYKKWNPESGHYAIGYHSVK
                     SHFDELATNKIQYVHAP"
     gene            11705..13540
                     /locus_tag="PC465_003016"
     CDS             11705..13540
                     /locus_tag="PC465_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF2650300.1"
                     /translation="MKISKKIVSLLTITFLTIMLYGNTSNASTKDTLTGSGRWETAIK
                     ISQAGWTKSESAVLVNDNSIADALSATPFAKAKDVPILLTQSNKLDSRTKAELKRLGV
                     KNVYLIGGSIALSSEIEKQLNAENISFERISGNSRYDTSLKLAEKLDREKSISKIVVV
                     NGEKGLADAVSVGAIAAQENMPIILSDSENGTEVADNFIDSKDIEKSYVIGGTYSISN
                     SVERSLPNATRIAGSSRSETNAKIIEEFYKDTDIKNIYVTKDGTRSKHDLIDSLAVGV
                     LASKNGSPILLAGNKLDSSQKDVLNTKIIDKVIQIGGLGNENVVEDVIDMQEETKYTV
                     ETIDELNVAIKKSDANDIIRFKPEKDKNITNSFKIETNKAITIEFDGIYKQSITIDMP
                     NGDIKNFGDIDNDLVINNIKNETLVNEGSIQGIDVYDENGCKIENEDSGEIWLITILK
                     NSKDVYILNRGEITKISNNSSSVTIKNSGNINTISGSEEPSISGKKPITNDTDKDEDK
                     KARGLYPKVESCIPALKDYVRITISTKPESSKYKIYYRVVDEKPSAKYVGEKISTKGW
                     SMVTISNQSFIERAKDGSYIEAVEIDTSNNEVSRWGKSSITDDGI"
     gene            complement(13588..13983)
                     /locus_tag="PC465_003017"
     CDS             complement(13588..13983)
                     /locus_tag="PC465_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HDF2650301.1"
                     /translation="MILKKYKETILYLFFGAFTTLVNIVSYLFFTRVILFNFMVANAL
                     AWILAVLFAYVTNKFFVFESKRIEIKFLFKEFLSFVSFRLLSGVVEMLIMYVMIDLLF
                     VNDVIVKIFTNIVVIVLNYLFSKMIIFKK"
     gene            14211..16622
                     /locus_tag="PC465_003018"
     CDS             14211..16622
                     /locus_tag="PC465_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp84"
                     /protein_id="HDF2650302.1"
                     /translation="MRKYKLKKLSKLLALLTVCFLIVSTIPVSAENHKTLDGVETAEY
                     SESYLQYLEDVKNGDTAKYNGVIPFPHEMEGTTLRNKGRSSLPSAYKSSVAYNPMDLG
                     LTTPAKNQGSLNTCWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDM
                     SGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATEPSNMDTAPTQFNVTDVVRLNK
                     DKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTNKRAPLNHAVAIVGWDDNYSKD
                     NFASDVKPESDGAWLVKSSWGEFNSMKGFFWISYEDKTLLTDTDNYAMKSVSKPDSDK
                     KMYQLEYAGLSKIMSNKVTAANVFDFSRDSEKLDSVMFETDSVGAKYEVYYAPVVNGV
                     PQNNSMTKLASGTVSYSGYINVPTNSYSLPKGKGAIVVVIDNTANPNREKSTLAYETN
                     IDAYYLYEAKANLGESYILQNNKFEDINTYSEFSPCNFVIKAITKTSSGQATSGESLT
                     GADRYETAVKVSQKGWTSSQNAVLVNGDAIVDALTATPFTAAIDSPILLTGKDNLDSK
                     TKAELQRLGTKKVYLIGGENSLSKNVQTQLSNMGISVERISGSDRYKTSISLAQKLNS
                     IKSVSQVAVANGVNGLADAISVGAAAADNNMPIILTNEKSELQGADEFLNSSKITKSY
                     IIGGTATLSSNLESKLSNPTRLAGSNRNETNAKIIDKFYPSSDLKYAFVVKDGSKSQG
                     DLIDGLAVGALGAKTDSPVVLVGNKLDESQKNVLKSKKIETPIRVGGNGNENAFNELN
                     TLLGK"
     gene            16919..18496
                     /locus_tag="PC465_003019"
     CDS             16919..18496
                     /locus_tag="PC465_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp5"
                     /protein_id="HDF2650303.1"
                     /translation="MKAPKTILTILTIALTLSSISIIPSYALTEEKLIGNGRYETAVK
                     ISQKAYSSSSNVVLVNDNSLADALSATPFAKAKGAPILLTESDKLDDRTEKEIKRLGA
                     KDIYLIGGTAVLNKDIENKLKGNGLNVERINGKDRYETSLILANKLKDIKDIKEVAVV
                     NGEKGLSDAVSVGAPAAQNKMPIILSSPKDGVEAFDKFIRDEKVIKAYVIGGTTSVSR
                     AVEKSLPNAERVSGKDRNETNAKVIEKFYTDTNLSNLYVTKDGSKNENQLIDSLAVGV
                     LAAKNESPVVLVGNKLNTKQRDILSTKKLNTITQVGGNGNEEAFDEIKSLQEKTVFEA
                     KTVEELTDMINIASPNDIINFKPKENTVNEAFRMVTNKPITVNIKGDCSKTLTVDMPN
                     GEVNNYATLVNVIVRNIGEGGFNNHDTITILSVRDKNGRVIENTRNSDIDTLMILASA
                     NDTKLINDGYIGKLIDNSSNSDITNNGTIDKKVNQVEDLEAKVDSIEKAIDSISQKVN
                     KIQDILDKLGFLKKFLS"
BASE COUNT         7738 a         2077 c         3451 g         5437 t
ORIGIN      
        1 ttcatatcat atatactcta taatatatgg aaaataaaga gaaaataaat ggaaaataat
       61 tacaatataa atataaaata taaaaatcat cagggggata tgaaaatgaa caaaaaaata
      121 ttatcattag gtctagcagt atcattaatc ttagtaaact tcaaaagtgt aaatgcatca
      181 tcagtagtag aaaaaatata cggtaaagat agatatgaaa cagcagcaaa gatagctgat
      241 aaacagactt atgaaacagt aattttagta aatacagaaa aatcacttgc agacggatta
      301 agtgcaagtg gattatcggg agctacaaaa gctccaatac tatttacaca acaaaataag
      361 ataccagcag acacaaatag atgtctaaaa aatatcaaaa aagcatatat aataggtaca
      421 gaagatacta taagtaaatc agtagaaaaa gaactagatt ctaaaaatat agaagtcaaa
      481 agaattggtg gagaagatag actaaaaaca agctatttaa tagctaaaga aatagcaact
      541 ataaaaaaag tggataaagt actattaact aatgcatata gtggagaagc agatgcaatg
      601 agtgtatcat cagtagctac tagagatgga gctccaatca tacttacaga tggaaagagt
      661 gtgccttttg atgtaaaaaa tattcaatca tattgtatag gttcagagga gataatgagt
      721 aatcttctag ttaaaaatac aaactcagta agaatagaag gaactgaccg atttgaaact
      781 aacaaaaacg taatagacta cttttttaat agtgcagatg gattctatgt atcagatgga
      841 taccaattag tagatgcaat agcagccgca ccacttacta aaaactctcc aatggtacta
      901 gtaaatgatg gaagcgataa aactgtatta gaaggagcta agaatataac ctctgtaggt
      961 gaaatagatg agaaggtaat acaacaatgt ataagtgctt caaagtcaaa tggacaaccc
     1021 ccaacaatta cagttggaag tacagaggta tataagggtg aaaagtttga cactggcaag
     1081 ttaaatatag tagctaaaga taacactggg aaggtattac caatagaagt tgatgggttt
     1141 atagatacaa atagagtagg tacatacata ttgacattaa aagctacaga cgaatgggga
     1201 aaaagtacag gaaaaagagt agaaataaaa gtgttggatg acaaatctca tgattacaac
     1261 agcccagaat ttaaaaaaat ggtatctact gaaatgtata acttaatcaa ttcctataga
     1321 aaagaaaaag gcaaagagcc tttggtagtg tctagtaggc tagaaggtat ggcaaatgca
     1381 tggtctaagt atatgatgga taaaaaagta tttgcacatt atatagatgg aaaaaatgct
     1441 ccacaagtat tttctgaatt tggaatgaga agtgaggaaa atatagcata tatttatata
     1501 gattctaaga acgttcaaac gacacaagat gcaaaagact tggcaaaggc tatatttgaa
     1561 gtgtggaaga agtctccaga atacaatgca aacatgctta gtgatgagtt ttatagtact
     1621 ggatttgggc tttatatatt atctgatggt caagtgcatg ctactcagga gtttttaaat
     1681 ggaaatgaag atagcttgta aaaaattcca taaatcttgt ttttttgtta atttactgat
     1741 attataaaat gaaaatcaca tctaaagtac tttttgtaat ctgttttgtt attgctttac
     1801 aggttatggt attttaggtg ttttttgttt tagtagttta tagattttga gggaatcact
     1861 actgaggatg taatttatga ttagctgaat tatataaaaa aattagtagg aggagtttga
     1921 tgaaggtaaa taagagagta ttatcaatag gattggcaat atcattaata atggcaggag
     1981 caccaaatat caatgcactt tcaagtatag aaaagataca agggaaagat agatatgaga
     2041 cagctgccaa aattgcacag aaacaaacat atgaaaatgt agtattagta aatacagata
     2101 atacactagc tgatggatta agtgcaagtg gattagcagg aacagttaaa gcacctatat
     2161 tattatcaca aagaaacagt ataccatcag acacagaaaa aatgttaaaa gatgtaaaga
     2221 aggtttatat aataggaact gaagattcaa taggaaaatc agttgaaaat gaattaaagc
     2281 aaaaagggat agaagttaaa agaataggtg gtaatgatag aattgaaaca agttatctta
     2341 tagcaaaaga aatagcttca ataaaaccta tagataaggt ttttataact aatggttata
     2401 caggtgaagc agatgctatg agtgcgtcat cagtagcatc aagagatgga gcacctataa
     2461 ttttaactaa tggtaaaaat gttccatttg agaaaaaaga aggtgtgcaa tgctatgctc
     2521 ttggttcaga ggagataata agtaatgatt tagttaaaaa aactaatgca gttagattag
     2581 ctggagaaga tagatttgag actaataaaa aagttataaa acatttttat agttcagcaa
     2641 aagaatttta tctttctaaa ggttatcaat tagtagatgc agttgctggt tcttctatag
     2701 ctaaaaatgc acctattgta ttggttgatg gaaatagtga taagtctgta cttagaagtg
     2761 ctgataaaat cacagcacta ggaggaatag atgaaaagac actagaacaa tgtttaagtg
     2821 catcatcact ggatgcaagt gcaccaacaa taactgttgg aaatttaaat atttatcaag
     2881 gtgataagtt tgatataagt aaacttaata tagtagcaaa ggatagcaat ggtaacgatt
     2941 tgacaccaga gcttatagga aatatcaata ctgataaggt tggtaaatac aaagttacta
     3001 taaaagctac tgatattggt ggaaagacta cctcaataag tgtagaagta aatgtacttg
     3061 aatataagac taatgatatg aatagtagtg agtttaaaag aatggtttct agtgaaatgt
     3121 ataatttggt aaattcatat agaaaagaaa aaggtaaaga gccattacaa gtttctaaaa
     3181 acttagaagg gctttctaat tcctggtcta agtacatggc agataaaggc caattttcac
     3241 atgtaataga tggtaaaaaa tctgttgaag tatttactgg atatgggttg agaagtgaag
     3301 aaaatatagc ttttgtacca cttgttacaa agagcactta tacaacaaaa gatgctagag
     3361 aactagcaaa tgtaatattt acagtttgga aaaagtcaga taaatataat gaaaatatgt
     3421 taaatagtga ttttgtatat actgggtttg gattatatat attgcctaat ggagaagtgt
     3481 atgctactca agaattttta aataagtaaa attaaatttt ttaagttatt aaatattgaa
     3541 atttaagggt ataaaaactc atatgcttgg gaaaaataat aatttcaaaa aaatgccttg
     3601 caaaaagaat aaaaatggat tattatagag atgtgagaaa tattaggaat atatggatga
     3661 ttattctatg tacataataa gagatgtaat tttaatataa tgttgggagg aatttaagga
     3721 atgaataaga aaaatatagc aatagctatg tcaggtttaa cagttttagc ttcggctgca
     3781 cctgtatttg cagatgatac aaaagttgaa actggtgatc aaggatatac agtggtacaa
     3841 agcaagtata agaaagctgt tgaacaatta caaaaaggaa tattagatgg aagtataaca
     3901 gaaattaaag ttttctttga gggaacttta gcatctacta taaaagtagg ttctgagctt
     3961 aatgcagcag atgcaagtaa attattgttt acacaagtag ataataaact agataattta
     4021 ggtgatggag attatgtaga tttcttaata acttctccag gtcaagggga taaaataact
     4081 acaagtaaac ttgttgcatt gaaagattta acaggtgctt cagcagatgc tataattgct
     4141 ggaacatctt cagcagatgg tgttgttaca aatactggag ctgctagtgg ttctactgag
     4201 acaaattcag caggaacaaa acttgcaatg tcagctattt ttgacacagc atatacagat
     4261 tcatctgaaa ctgcggttaa gattactata aaagcagata tgaatgatac taaatttggt
     4321 aaagcaggtg agacaactta ttcaactggg cttacatttg aagatgggtc tacagaaaaa
     4381 attgttaaat taggggacag tgatattata gatataacta aagctcttaa acttactgtt
     4441 gttcctggaa gtaaagcaac tgttaagttt gctgaaaaaa caccaagtgc cagtgttcaa
     4501 ccagtaataa caaagcttag aataataaat gctaaagaag aaacaataga tattgacgct
     4561 agttctagta aaacagcaca agatttagct aaaaaatatg tatttaataa aactgattta
     4621 aatactcttt ataaagtatt aaatggagat gaagcagata ctaatggatt aatagaagaa
     4681 gttagtggaa aatatcaagt agttctttat ccagaaggaa aaagagttac aactaagagt
     4741 gctgcaaagg cttcaattgc tgatgaaaat tcaccagtta aattaactct taagtcagat
     4801 aagaagaaag acttaaaaga ttatgtggat gatttaagaa catataataa tggatattca
     4861 aatgctatag aagtagcagg agaagataga atagaaactg caatagcatt aagtcaaaaa
     4921 tattataact ctgatgatga aaatgctata tttagagatt cagttgataa tgtagtattg
     4981 gttggaggaa atgcaatagt tgatggactt gtagcttctc ctttagcttc tgaaaagaaa
     5041 gctcctttat tattaacttc aaaagataaa ttagattcaa gcgtaaaagc tgaaataaag
     5101 agagttatga atataaagag tacaacaggt ataaatactt caaagaaagt ttatttagct
     5161 ggtggagtta attctatatc taaagaagta gaaaatgaat taaaagatat gggacttaaa
     5221 gttacaagat tagcaggaga tgatagatat gaaacttctc taaaaatagc tgatgaagta
     5281 ggtcttgata atgataaagc atttgtagtt ggaggaacag gattagcaga tgccatgagt
     5341 atagctccag ttgcatctca attaagaaat gctaatggta aaatggattt agctgatggt
     5401 gatgctacac caatagtagt tgtagatgga aaagctaaaa ctataaatga tgatgtaaaa
     5461 gatttcttag atgattcaca agttgatata ataggtggag aaaacagtgt atctaaagat
     5521 gttgaaaatg caatagatga tgctacaggt aaatctccag atagatatag tggagatgat
     5581 agacaagcaa ctaatgcaaa agttataaaa gaatcttctt attatcaaga taacttaaat
     5641 aatgataaaa aagtagttaa tttctttgta gctaaagatg gttctactaa agaagatcaa
     5701 ttagttgatg ctttagcagc agctccagtt gcagcaaact ttggtgtaac tcttaattct
     5761 gatggtaagc cagtagataa agatggtgaa gtattaactg gttctgataa tgataaaaat
     5821 aaattagtat ctccagcacc tatagtatta gctactgatt ctttatcttc agatcaaagt
     5881 gtatctataa gtaaagttct tgataaagat aatggagaaa acttagttca agttggtaaa
     5941 ggtatagcta cttcagttat aaacaaatta aaagatttat taagtatgta atataaatat
     6001 aataatataa aaaggcttct tatatgagaa gtctttttat attatgtttt cgaatacaaa
     6061 aaaagagact aaatttagtc tcttttttat gtgagaaata cttaaatata taaagatgta
     6121 atttatttaa gtatgattat tatactatac aataaaataa ttgtctacta ttctataatt
     6181 ttaaggtata ataataattg tatgataaaa aaggaggtca aaaaatatgt cagttttaga
     6241 tgcaatctta gataaagcgg atgaacaaga aattaaaaaa ttaaatttaa tagtagataa
     6301 aatagaatct ttagaaaaag atatggaaat caaagagaat gaacaattaa aagaaatgac
     6361 aaatactttt agacttagat tagacaaagg tgaaagtttg gatgatatac ttccagaagc
     6421 atttgctgtt gttagagagg tctcaaaaag agttttagga atgcgtcaat ataaagttca
     6481 gttaattgga ggtatagtaa ttcatcaagg aaagatagct gagatgaaga ctggtgaggg
     6541 gaaaacttta gttgaggtag ctccagtata tctaaatgct ttaacaggaa aaggtgtaca
     6601 tgtaattaca gtaaatgatt atttggcaga acgtgataaa gaacttatgc gtccagtata
     6661 tgaattttta ggattgactg taggtgtaat tttatctaac caagacccaa gtataagaaa
     6721 agaacaatat aaatgtgata taacttatgg aacaaatagt gaatttggat ttgactattt
     6781 aagagataat atggtgccag atttgtctca taaagtacaa agggaactaa actttgccat
     6841 agtagatgag atagactcaa tattaataga tgaagctaga actccactta ttattgcagg
     6901 agatggtgat gaagatttaa aactttatga gttagcaaat aactttgtaa aaactgttaa
     6961 agaagaagac tttgagatgg atagaaaaga taaaactata gcattaacag caagtggtat
     7021 aagcaaagct gagtcatttt ttggtataac aaaccttact gatataaaga atatagaatt
     7081 atatcatcat ataaatcaag ctttaagagg tcataagctt atggaaaaag atgttgacta
     7141 tgttatctca aatggagaag taatgatagt tgacgaattt acaggaagag taatggatgg
     7201 tagaagatat acagatggac ttcaccaagc tatagaagcc aaagaaggtg ttgagataaa
     7261 gaatgaatct aaaactatgg ctactgtgac ttatcaaaat ttcttcagac tatatgaaaa
     7321 actttctggt atgactggta ctgcaaagac agaagaaggg gaatttgagt caatctataa
     7381 attaaatgtt gtccaaatac caactaatag accagttatt agagctgatt tgcatgataa
     7441 ggtatttaaa acagaagaag aaaagtatag tgctgttgta gaagaaataa taaggataca
     7501 taagactaga cagccaatac tcgtgggaac agtttctgtt gaaaaatctg agaagttatc
     7561 taaaatgctt aagaagcaag gtattaagca tcaagtctta aatgctaaac aacatgataa
     7621 agaggcagag gtaatttcta aagctggtaa attagatgct ataacgattg ctacaaatat
     7681 ggcaggtaga ggtacggata tttctctagg tgcaggagat aaagaagaag aagaaaaagt
     7741 taaaaattta ggtggtcttt atgttatagg aacagaaaga cacgaatcaa gaagaattga
     7801 caatcagctt agagggcgtt ctggtcgtca aggagaccca ggtacatcaa gattctttgt
     7861 aagtcttgaa gatgatgtaa taaagcttta tggtggaaaa actatagaga aacttatgaa
     7921 gagaacaagt tcaaaggaaa atacggctat tgaaagtaaa gcacttacaa gggctataga
     7981 aagagcacaa aaaggtgtag aaggtaaaaa ttttgaaata agaaaaaatg ttcttaaata
     8041 tgatgatact attaatgagc aaagaaaggt tatatataat gaaagaaata aagtgttaaa
     8101 tgatgaagat ataaaagaag atattcaaaa aatggttaaa gacatcatac aagaagcagg
     8161 agaaacttat ttaattggaa gaaaaagaga ttattatgga tattttaaac atttatatag
     8221 tacatttatg cctgcagata cattactaat acccggtgta gataaaaaaa gtgtccaaga
     8281 gataattgat agcacatatg aaatttcaaa aagggtttat gacttgaaaa agatgatgat
     8341 tggtattgat aaagttgcgg agttagaaaa aacagtactt ttaaaagtgg ttgatcaata
     8401 ctggatagat catatagatg ctatggaaca gttaagacag tatataggtc ttaaatctta
     8461 tgctcaaaaa gatccgttta aagaatatgc tttagaagga tatgatatgt ttgaagcttt
     8521 aaataaaaat ataagggaag caacagtaca atacttatat aaatttaact aaaaaagttc
     8581 atgtaatttt tattaaatga aaaataaaat attttgattc tttatattgt aattacaatt
     8641 aaataattaa ggaatacaaa tgaaaaagaa gctgaaaatc agcttctttt tctgtgtgag
     8701 aaatacggaa aaaagagatg cttgaaattt ctttcttcca tttaatatta tactataaag
     8761 aagatgaaaa gtctattagt tataaactgg attattaaaa aaaattacaa ttttgttact
     8821 tttttgtata cataaatatt aaaaaaataa aatataagaa aaagtttata tcttttggtt
     8881 aattattaca ataagtctca tttattgaaa taatatcaaa tatatattat aattggtaaa
     8941 taaggaaaaa ataataaaaa tttgaatttt ttagggggaa aataccatga ataaaaaaaa
     9001 tctttctgta attatggctg ctgcaatgat aagtacatca gtagctccag tttttgctgc
     9061 agaaactaca caggtaaaaa aagaaacaat aactaagaaa gaggctacag aattagtttc
     9121 gaaagttaga ggtttaatgt ctcaaaagta tacaggaggt tctcaagttg gacaaccaat
     9181 atatgaaata aaagttggtg agactttatc aaaattaaaa ataataacta atatagatga
     9241 attagaaaaa ttagtaaatg ctttgggaga aaataaagaa cttattgtaa ctataacaga
     9301 taaagggcat ataacaaata gtgcaaatga agtagttgca gaagcaactg aaaaatatga
     9361 aaattcagca gacctttccg ctgaagctaa ttctataaca gaaaaagcta aaactgaaac
     9421 caatggaatt tataaagttg cagatgtaaa agcttcatat gatagtgcta aagataagtt
     9481 agttataact ttaagagata aaacagaaac agtaacttct aaaactatat atgtaggtat
     9541 tggtgatgaa aaagttgatt taacagcaaa tccagttgat tcaactggaa caaatttaga
     9601 cccttctgca gaaggattta gagtaaataa aatcgataaa ctaggtgtag caggagctaa
     9661 aaatattgat gatgtccaat tggccgaaat aactataaaa aatagtgacc taaatacagt
     9721 ttcaccacaa gatttatatg atggatatag attgactgtt aaaggtaata tggtagcaaa
     9781 tggtacatca aagtcaatta gtgatatttc agcaaaagat tcagaaacag gaaaatataa
     9841 atttactatt aagtatactg atgcatctgg aaaagcaaca gagcttactg tagaaagtac
     9901 taatgaaaaa gatttaaaag atgccaaagc tgcattagaa ggtaattcaa aggttaaatt
     9961 gatagctgga gatgatagat atgcaactgc agtggctata gcaaaacaaa caaaatatac
    10021 tgacaatata gttatagtta attcaaataa actagttgat ggattagcag ctacaccact
    10081 tgctcaatct aaaaaagcac ctatattatt agcatccgat aatgaaatac caaaagtaac
    10141 tttagattat ataaaagata taattaagaa aagcccatca gctaaaatat atatagtagg
    10201 tggagaatca gcagtatcaa atacagctaa aaagcaatta gaatcagtaa ctaagaatgt
    10261 tgaaagacta gctggagatg atagacatat gacttctgta gcagtagcaa aagctatggg
    10321 gtcttttaaa gatgcatttg tagtaggtgc gaaaggggag gctgatgcta tgagtatagc
    10381 tgccaaagct gctgaactta aggctcctat aatagtaaat ggctggaatg atctttcagc
    10441 agacgctatc aaattgatgg atggaaaaga gattggtata gttggtggtt ctaacaatgt
    10501 atctagtcaa attgaaaatc aacttgctga tattgataaa gatagaaaag ttcaaagagt
    10561 tgaaggagaa acaagacatg ataccaatgc taaggttata gaaacatatt atggcaagct
    10621 agataaacta tatatagcaa aagatggata tggaaataat ggtatgctag tagatgcatt
    10681 agcagcagga cctctagcag caggtaaagg tccaatactt ctagctaaaa ctgatataac
    10741 agactcacaa aagaatgcac ttagtaaaaa attaaatctt ggtgcagaag taactcaaat
    10801 aggtaatgga gttgaattga cagtaataca aaagatagct aaaatactag gttggtaata
    10861 acttatactg tggagaagat tccttaatta atacaggaat ctttttctat aattatgcta
    10921 tttattgtaa attataacat tttataaagt aggaggatgt agtagtggta gatgcaactt
    10981 tattttttac accacatcaa gatgatgaaa ccttaagtat gggaagtgct ataattgaac
    11041 atgttgaaaa aagtgataca catgtcatat tatgtacaga tggtagtaaa tctataataa
    11101 gaaaagtttt ggatgatgga gggtcatgtt cttatcatat taaagatgtt cataaatact
    11161 ctttatcaga aaatgaattt tcaaaagata gagatgaaga atttaaggat agctgtgaag
    11221 caatgggtgt aaaagaaagt aatatacata tagaagataa tagagcacat gatggtgagt
    11281 taagtaaaga aaaggcaagg gaaataatac ttaagtactt agaagaatat ccagatgcaa
    11341 aagtaaaaac tgttactccg tttaaagcta gtggaataca tgaagaccat agggcattag
    11401 gagaagctgc actagagtta tataaagaag gcaaaataaa agatttaaga ttttatgtag
    11461 aaccatatga ctataaggat tttaaaaaag ttaatccaaa tgtagaggta tggaaggtat
    11521 tacctagtca agaagagaaa ttattaagtg caatgaatgc atataaaaaa tggaatcctg
    11581 aaagtggaca ttatgctata ggataccatt cagtaaaatc tcattttgat gagctagcta
    11641 caaataaaat acagtatgta catgctccat aaaatattat gaaagaatta ggaggtaaga
    11701 attaatgaaa atatcaaaaa agatagtgtc cttgttaact ataacatttt taactattat
    11761 gttatatgga aatacatcta atgcatctac aaaagataca ttaacaggtt ctggaagatg
    11821 ggaaacagca ataaaaataa gtcaagctgg atggacaaag tctgaaagtg ctgtattagt
    11881 aaatgataat tcaatagcag atgctttatc agctactcca tttgcaaagg caaaagatgt
    11941 accaatatta ttaactcaaa gtaataaatt ggatagtaga acaaaagcag aattaaaaag
    12001 acttggtgtg aaaaatgtat atttaatagg tggttcaatt gcattaagtt cagagattga
    12061 aaagcagtta aatgcagaaa atataagttt tgaaagaata tctggaaata gtagatatga
    12121 tacttcttta aaattagctg aaaagctaga tagggaaaaa tctatatcta aaatagtagt
    12181 agtaaatgga gaaaagggtc ttgctgatgc agtgagtgtt ggagctatag ctgctcaaga
    12241 aaacatgcca ataatacttt ctgattcaga gaatggaact gaagtagctg ataattttat
    12301 agatagtaaa gatatagaaa aatcgtatgt aataggtggt acatattcta tttctaattc
    12361 tgtagaaaga agtttaccaa atgcaacaag aatagcaggt agtagtagaa gtgagacaaa
    12421 tgcaaaaatt atagaagaat tttacaaaga tactgatata aaaaatattt atgtaacaaa
    12481 ggatggtaca aggagtaagc atgatttaat agattcttta gctgtgggtg tattagcttc
    12541 taaaaatggt tctccaatac ttttagcagg aaataagcta gatagttctc aaaaagatgt
    12601 gttaaacact aaaattatag ataaagttat tcaaattggc ggattgggta atgaaaatgt
    12661 tgtagaagat gtaatagata tgcaagaaga aactaagtat actgttgaaa ctattgatga
    12721 acttaatgtt gctataaaaa aatcagatgc aaatgacatc ataagattta agccagaaaa
    12781 agataaaaat ataactaatt cttttaaaat agaaacaaat aaagctataa ctattgaatt
    12841 tgatggtata tataaacaat caataactat agatatgcca aatggagata taaaaaactt
    12901 tggggacata gataatgatc tagtaataaa taatataaaa aatgagactt tagttaacga
    12961 aggaagtata caagggatag atgtttatga tgagaatgga tgtaaaatag agaatgagga
    13021 ttctggagaa atatggctta taacgatact taaaaattca aaagatgtat atattttgaa
    13081 tcgtggagaa ataactaaaa tatctaataa ttcttctagt gtaacaataa aaaattcagg
    13141 taatattaat actataagtg gaagtgaaga accatcaata agtggtaaaa aacctataac
    13201 taatgataca gataaagatg aagataaaaa ggcacgtggt ttatatccta aagtagaatc
    13261 ttgtatacct gctttaaaag attatgtaag aataactata tcaacaaaac cagagagttc
    13321 aaagtataaa atttattata gagtagttga tgaaaaacca tctgcgaaat atgttggaga
    13381 aaaaattagt actaaaggtt ggagtatggt tacaatatca aatcaatctt ttattgaaag
    13441 agccaaagat ggatcatata tagaagcagt agaaatagat acctcaaata atgaagtttc
    13501 acgatgggga aaatctagca ttacagatga tggaatttag acattaaact tattcatttt
    13561 gcagattact atttagtaat ctgctattta ttttttaaaa attatcatct tgctaaacaa
    13621 gtaatttaaa actataacaa ctatattagt aaatattttt acaataacat catttacaaa
    13681 aagcaaatca atcattacat acataattaa catttcaacg acaccagaaa gtagcctaaa
    13741 actaacaaaa gacaaaaatt ccttaaataa gaactttatt tcaattcttt tactttcaaa
    13801 cacaaaaaac ttattagtaa cataagcaaa taaaacagca agtatccatg ccaaagcatt
    13861 tgcaaccata aaattaaata aaataactct agtaaaaaat aaatacgaaa ctatatttac
    13921 aagagtagta aatgctccaa aaaataaata taatattgtc tctttatact tttttaaaat
    13981 caaatataat cctcctaagc taatttaata taaatatact taaagatact aacaaacatt
    14041 agtatagcac atctattaat aaatcaatat atcttaaaat attataaaaa ataaaactat
    14101 aatattctat aattaatatg tactcataat ccatatttta tcaaaataaa atatgacctt
    14161 aatttagaaa tctgatataa taaaaattaa atacatataa gggggtaaac atgagaaagt
    14221 acaaattaaa aaaattgtca aagctactag cattgttgac agtttgcttt ttaatagtgt
    14281 caacaatacc tgtctcagca gaaaaccata aaactctaga tggagtagaa actgcagagt
    14341 attctgaaag ctatcttcaa tacctagaag atgtcaaaaa tggagacaca gcaaaatata
    14401 atggagtaat accttttcca catgaaatgg aaggtacaac acttcgaaat aagggtagaa
    14461 gtagtcttcc atcagcatat aaatcaagtg tagcatacaa cccaatggat cttggtctta
    14521 ctacaccagc aaaaaatcaa ggaagtctta atacatgctg gtctttttca ggtatgtcaa
    14581 ctttagaagc atatcttaaa ttaaaaggat atggaacgta tgacttatca gaagaacatt
    14641 taagatggtg ggcaactggt ggaaaatatg gatggaactt agatgatatg tcagggagtt
    14701 caaatgtaac agctatagga tatctgacag catgggcagg tcctaagtta gaaaaggaca
    14761 taccatataa tcttaaatct gaggcacaag gtgcaactga accttcaaat atggatactg
    14821 cacctactca atttaatgta acagatgttg ttcgtcttaa taaagataag gaaactgtaa
    14881 agaatgctat aatgcaatat ggttcagtga catcaggtta tgcacattat tcaacatatt
    14941 ttaataaaga tgaaacagca tataactgta caaataagag agctccatta aatcacgctg
    15001 tagcgatagt aggatgggat gataattatt caaaagataa ttttgcatct gatgtaaaac
    15061 cagaatcaga tggagcatgg ttagtaaaaa gcagttgggg agagtttaac tctatgaaag
    15121 gattcttctg gatttcttat gaagataaaa ctctactaac agatacagat aactatgcaa
    15181 tgaaatcagt atcaaaacca gatagtgata aaaaaatgta ccaacttgaa tatgctggtc
    15241 ttagcaagat aatgtcaaat aaagtaacag cagcaaatgt atttgatttt agcagagact
    15301 ctgaaaaact tgattctgtt atgtttgaaa cagactctgt aggagcaaaa tatgaagtat
    15361 attatgcacc agtggtaaat ggagttcctc aaaacaattc aatgacaaaa cttgcaagtg
    15421 gaacagtatc atattctgga tacataaatg tacctactaa ttcttacagc ttaccaaaag
    15481 gtaaaggagc aatagtagta gttatagaca acacagcaaa tcctaataga gaaaaatcaa
    15541 ctttagcata tgaaactaat atagatgcat attatttata tgaggctaaa gcaaacttag
    15601 gtgaaagcta catacttcaa aacaataagt ttgaggatat aaatacatat agtgaatttt
    15661 ctccttgtaa ctttgttata aaagctataa caaaaacatc ttctggacaa gctacttcag
    15721 gagaatcttt aactggagca gatagatatg aaacagcagt taaagttagt caaaaaggat
    15781 ggacttcttc acaaaatgca gtattagtaa atggagacgc aatagtggat gctttaacag
    15841 ctacaccatt tacagcagca atcgactctc caattctttt gacaggaaaa gataacttag
    15901 attcaaaaac taaggcagag ttacaaagat taggaactaa aaaagtttat ctaataggtg
    15961 gagaaaattc tttaagcaag aatgtacaaa ctcaacttag taatatgggt atatcagtag
    16021 aaagaatttc aggtagtgat agatacaaga ctagtatatc tctagctcaa aagttaaata
    16081 gtataaaatc tgtttcacaa gttgcagtgg caaatggtgt aaatggactt gcagatgcaa
    16141 taagtgttgg tgcagcagct gctgataaca atatgccaat aatacttact aatgaaaaaa
    16201 gtgagttgca aggtgctgat gagtttttaa attcatcaaa aataactaag tcttatataa
    16261 ttggtggaac agctacttta tcatcaaatt tagaaagtaa gctttcaaat ccaacaagac
    16321 ttgcaggaag taatagaaat gaaactaatg ctaagataat agataaattc tatcctagct
    16381 cagatttgaa atatgctttt gttgttaaag atggttcaaa gagtcaagga gacttgatag
    16441 atggactagc agtaggagca ttaggtgcta aaactgattc accagtagtt ctagttggaa
    16501 ataagttaga tgaaagtcaa aaaaatgtac ttaagtctaa gaaaatagaa actcctatta
    16561 gagttggtgg aaatggaaat gaaaatgctt ttaatgaact aaatactctt ttaggaaaat
    16621 agtgaatgga aagatagtaa ggatatacat tttattatta aaaaatgttc aatagaagtt
    16681 tataaatata aaataacaaa aaggggtgtc tcaaaatgaa ctttttagtt catgaggcac
    16741 tcttttttgt tgttttatat ttttatcatt taaataatga aaaataggct tgtctatatt
    16801 tttagatagt tttcttatta ttgatgaaaa atgtaataat tttaaactgt aaaatagtgt
    16861 aaagttattt tataatataa atatagtaag attttaaaca aaataagggg gaataataat
    16921 gaaagcacca aaaactattt taacaatact gacaatagcg cttactttaa gtagcatttc
    16981 tataatacca tcatatgcac ttacagagga aaaattaata ggtaatggta gatatgaaac
    17041 tgctgtaaag ataagtcaaa aggcatacag ttctagttct aatgtagtgt tagttaatga
    17101 caattcatta gctgatgcac tttcagccac accatttgca aaggctaaag gagcaccaat
    17161 acttttgaca gaaagtgata agctagatga taggactgaa aaagagataa aacgtctagg
    17221 agctaaagat atttatttga taggaggtac tgctgtactt aataaagata tagagaacaa
    17281 gttaaaaggt aatggactta atgtagaaag aattaatggt aaggatagat atgaaacttc
    17341 actgattttg gctaataagc ttaaggatat aaaagatatt aaggaagttg ctgtagtaaa
    17401 tggtgaaaaa ggattaagtg atgctgttag cgttggagca ccagcagctc aaaataagat
    17461 gcctataatt ttgtctagtc ctaaggacgg agtagaagca tttgataaat ttataaggga
    17521 tgagaaagtt ataaaagcat atgtaattgg aggtacgact tcagtttcaa gagctgtaga
    17581 aaagagtctt cctaatgcag aaagagtgag tgggaaagat agaaatgaga ctaatgctaa
    17641 ggtcatagaa aagttttaca ctgatacaaa tttaagtaat ttatatgtaa ctaaggatgg
    17701 tagtaaaaat gagaatcaac taatagactc gttagctgtt ggagtattgg ctgcaaaaaa
    17761 tgagtctcct gttgttttgg ttggtaataa attaaacaca aaacaaaggg acatacttag
    17821 tactaaaaaa ttaaatacta taacacaggt aggtggaaat ggaaatgaag aagcttttga
    17881 tgaaattaaa agtctacaag aaaaaactgt gtttgaagca aaaactgttg aggaattaac
    17941 tgatatgata aatatagcaa gtcctaatga tattataaac tttaaaccaa aagagaatac
    18001 tgtaaatgaa gcttttagaa tggtaacaaa taaaccaata actgtgaata taaagggtga
    18061 ttgttcaaag actcttacag tagatatgcc taatggtgaa gtgaataact atgctacttt
    18121 ggtaaatgtt atagttagaa atattggaga aggtggattt aataaccatg atacaatcac
    18181 tatattgtca gttcgtgaca aaaatggtag agttatagaa aatactagaa attcagatat
    18241 agatacgttg atgatattag cttctgctaa tgatacaaaa ttgattaatg atggatatat
    18301 aggaaaactt atagataatt catctaatag tgatataact aataatggta ctatagataa
    18361 aaaagttaat caggttgaag atttagaggc taaagtagat tcaattgaaa aagctataga
    18421 ttctataagt caaaaagtca ataaaataca agatatacta gataagcttg gatttctaaa
    18481 gaaatttctt agctaagaat atatatattt aagtgaagtg tgtgttgtaa ttgttctaaa
    18541 tttatgtagt taaacaggtt tatatacaaa tagatttata gataaatatg tagtttagta
    18601 tatatttgaa taagctttgg ggaggtaaca tggggattgg aattgaatgt aacaaaaaaa
    18661 taaataaaag tattgacaaa actagaataa agaaaaataa tct
//
LOCUS       DAMJXI010000069        18632 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.072, whole genome shotgun sequence.
ACCESSION   DAMJXI010000069 DAMJXI010000000
VERSION     DAMJXI010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18632
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.072"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            118..531
                     /locus_tag="PC465_003020"
     CDS             118..531
                     /locus_tag="PC465_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2650304.1"
                     /translation="MELEITEKIEKQDEDTIFQGLLKYNLARLEDKNPVDLGIYIRDK
                     AGKIVAGFIGVTHGNWLSIKYLWVSEKLRYKGTGSQLLYKAEKIAKERGCKYVFLDTF
                     SFQAPKFYEKFGYHKVFSLENYPLTGKRYYYRKIL"
     gene            722..1939
                     /locus_tag="PC465_003021"
     CDS             722..1939
                     /locus_tag="PC465_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
                     /protein_id="HDF2650305.1"
                     /translation="MLGKKCMDYLQTLGKISSTTNGLTRLILTQEHKKSIDLISSWME
                     GLNLDIEIDDIGNVIGTYKSSFPNAPTLVVASHQDSVKCGGIFDGMLGIIVPLVGLEE
                     AKHNNRSYPFNIKLIAFAEEEGTRFETSLMGSKVFAGTFKEELLKSVDENGITLEEAV
                     TKFGFNTKNLTNLHPRKDVDAYLEFHIEQGPVLENESLPAGIVSSITGFKSFKISVNG
                     KSGHAGTLPMNMRLDAGCCACECVLAIEKVAKTTADLVATVGKMNFYPSSSNVVPERA
                     EFTLDVRSCSQEILDNSVEKIFNEISHICENRKLNYTSELAFENVPVPCSNKITKIIE
                     KSFIDLNLNPFYIYSGAGHDAQEMDNITDIGMVFIRCAGGVSHNPNESVSVDDLDTAV
                     KIFLKILDNLDLK"
     gene            2101..2799
                     /locus_tag="PC465_003022"
     CDS             2101..2799
                     /locus_tag="PC465_003022"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HDF2650306.1"
                     /translation="MNEKLIGILAGMGPRSTAPFVDLIIDECQSQYGAKYDDEFPKMM
                     IYSLPTPFYIDRPINHELMKETIIDGLQKLESTGVNFIAMPCNSAHIYFKELKESINI
                     PILNIVEETVKKLPTISQKVTLFSTSSTFESTIYQNGIIHNGHEFIFKDEWQIKLNNL
                     IQNIKMDKENPHNIDIWNKLIEDVKNESIENIVIACTDLNVVLEKSYPSINIVDSSKC
                     LAESVVNKYLKLVK"
     gene            complement(3019..3636)
                     /locus_tag="PC465_003023"
     CDS             complement(3019..3636)
                     /locus_tag="PC465_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4878 domain-containing protein"
                     /protein_id="HDF2650307.1"
                     /translation="MKKIILALTTFLLAISLTACSSAKPEDTIDSFFNSAKKFDFEGM
                     NKVMENNDEKYKDILKELDTKDPNAQYVLDYLKQNASKITYTIKDSEVKGDKATIKVE
                     CKFIDSTPLLQEIVAEAFTKMIGMSFSGQDLTDEKTTEMLVSIMKEKQKSVKETYVTK
                     NVEFECSKKDNKWIISSVNDAVADVLLSNLVTAGQEFSNSMNTLE"
     gene            complement(3763..4785)
                     /gene="argF"
                     /locus_tag="PC465_003024"
     CDS             complement(3763..4785)
                     /gene="argF"
                     /locus_tag="PC465_003024"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HDF2650308.1"
                     /translation="MNNISLKGKSFLTLKDFTKEEIRYLLTLSSYLKTKKKVGIKGDL
                     LQGKNIALLFEKTSTRTRCSFEVAAHDEGAHVTYLGPNDCHMGKKESVSDTAKVLGRF
                     YDGIEFRGFKQETVESLAKYSGVPVWNGLTDEYHPTQILADFLTVIENVDKDLNKVKF
                     VYVGDARNNMGNSLMIGCAKMGIHFVALAPKELWPNEELVKEMKEIAKKSKGDIMLTE
                     NIDDVKGADVIYTDVWVSMGEEEQYEARINQLKDYQVNMDMIKKTENENVIFLHCLPA
                     FHDLETKVAQEIYEKFGLSELEVTNEVFNSKYSKVFEEAENRMHTIKAVMVSTMTDVN
                     MNNNLI"
     gene            complement(4894..6081)
                     /locus_tag="PC465_003025"
     CDS             complement(4894..6081)
                     /locus_tag="PC465_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HDF2650309.1"
                     /translation="MNNDNTISKWNEYFIDTYNQPNFVIDYGEGSCFFDTNGNKYIDF
                     TSGYGVSSLGYSNSNLKNALKEQVDKLLHTSNLYFNEPVLYSGEKIINSSGMAKVYFC
                     NSGTEANETAFKIARKYSSDKYGNGRGTIISLKDSFHGRTMMSLMATGMDKYHKYFYP
                     LPEGFKYIERNNIEDLKNNLDSTVCAIILEAIQGEGGVNVLEKDYVLQIVKICQEKDI
                     VVIFDEVQCGIGRTGKLFGYEYFDVKPDIVTVAKGLGAGIPVGGVLVNKKLSKVLGKG
                     DQGTTFGGNLLAMVAASVVLDEISKDGFYNEVLEKGNYIRKSIESFNNKVVLKTKGIG
                     LMIGIETNIESSIIEEKARKKGLLILTAGKNVLRFLPPLTISYKEIDEALEILKDILL
                     EIN"
     gene            complement(6111..6971)
                     /gene="argB"
                     /locus_tag="PC465_003026"
     CDS             complement(6111..6971)
                     /gene="argB"
                     /locus_tag="PC465_003026"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HDF2650310.1"
                     /translation="MINIEKANTLIEALPYIEKHQGKTIVVKYGGSAMKKDGLKESVM
                     EDLVLMSYVGINIVLVHGGGAEINKMLAKVDIESKFVNGLRYTDEETMEIVKMVLAGK
                     VNKDLVNKIHTKGGKAVGLCGIDNNMILCDPYKNYELGFVGEIKKVNVELIESCLKSG
                     YISVIATIGVGDDGETYNINGDTAASAIAKELNADKLILLTDVPGLLREPDEEKSLIT
                     EVILEDVDKLFEEGIITGGMIPKIEGCVDALNNGVNRVHILDGRVPHSIITELFTDSG
                     IGTLIRKENE"
     gene            complement(6986..8203)
                     /gene="argJ"
                     /locus_tag="PC465_003027"
     CDS             complement(6986..8203)
                     /gene="argJ"
                     /locus_tag="PC465_003027"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HDF2650311.1"
                     /translation="MEIIKGGVTVSEGFFASGIHCGLRKNKEKRDLALVYSDVLCDAA
                     AVVTQNKVKGNPVYVTQEHIKNGKAQAIIVNSANANTFNGKEGLINAYKMAKFTSDKL
                     NIKESDVLVASTGVIGKPLNIDLIEENMDELVNNLSKQGHIGAREAIMTTDIIKKEIA
                     VAIMYGDKKITIGGMAKGSGMIHPNMATTLGFITTDANIDGVLLKEALKIAVDKSFNR
                     VSVDGDTSTNDMVMILANGKAKNDRINKKDEHYQVFLSALTYVCIELAKLVAKDGEGC
                     TKLIECYINGALSEAHAVKLAKTVISSSLVKTAVFGADANWGRILCALGYAGEEIDME
                     KVDIIFESMKGYIEVCKNGNGLDFNEEKAKKILEDDEISILVDLNMGNARGNAWGCDL
                     SYDYVRINGSYRN"
     gene            complement(8244..9278)
                     /locus_tag="PC465_003028"
     CDS             complement(8244..9278)
                     /locus_tag="PC465_003028"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HDF2650312.1"
                     /translation="MNKIKVGIIGATGYVGAELIRLLMNHDKVEVRAIGSNSYVGKDI
                     VDIYPSIGYKNNMICIENEKVIDMCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADF
                     RIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKEDIKDADIIANPGCYPTSISLPLM
                     PLLSSKLIKNNNIIIDSKSGLTGAGRELSISSHFTEVNENITAYKIGKHRHTPEIEQN
                     LSESCKEKVSVVFTPNLIPVNRGILSTIYCTKEDNISINDIHRKLTDYYEFKEFIEIL
                     PLDKIASLKNVRFSNKCVISLHENGDTLIICSAIDNMIKGAAGQAIQNMNIIFGIEEN
                     TGLKNIAPSF"
     misc_binding    complement(9532..9745)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(10049..11140)
                     /gene="ytvI"
                     /locus_tag="PC465_003029"
     CDS             complement(10049..11140)
                     /gene="ytvI"
                     /locus_tag="PC465_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HDF2650313.1"
                     /translation="MNEQDHTSYQNKQRFLINFCYLVVILGLLMLLGKYAFSVLLPFV
                     FAFLIASLLNKPVLYISEKLLIKRGIVATISVFLFFLIAGIIVSVIGTYLIYGIKEIF
                     HFLPTMFEELVIPLTETVIKEVELFSGSFNFSFIELIEANMPVLMNEMSVFIVSLSNN
                     IVSGITDIVSSVPLLFMKTIITIVASIFIAIDYPTIKRFIVLQIPKNKSYLLAEAKAF
                     TIDTIIKCGFSYLLIFAITFSELYVGFAIINISYAGIIALFIALLDILPVLGTGSILI
                     PWGIISLFLGDYSMALGIALLYIVITIIRNIIEPKLVGKHMELHPVLALASMLTGLHF
                     FGFIGLFGILLLIAFLKKLNDKEIIHILH"
     gene            complement(11155..12546)
                     /locus_tag="PC465_003030"
     CDS             complement(11155..12546)
                     /locus_tag="PC465_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase family protein"
                     /protein_id="HDF2650314.1"
                     /translation="MKRRLAGEWEPIKGVMLAWPPFLPHKYIVDLTQNYSVYMCVPNK
                     EEIEIAKYYLSKWGGNLKNLIFCIAPQGFDTPWVRDWGMHPIFDENGKLFLAGAEYKM
                     STPFVSINKPEIMFDCEHNLLTTNSYEQKEDQSQELIAKQIGLPFMKLPYALTGGNLM
                     SDGFNKLMSMHILQTENRAKGISDEEFFSMVARDTGMNEYYIFSNFADYGLQHIDCYL
                     KIIDEETLLVSRTPKEHYLYERYEKILEEVKKVETRYGRPFKIFRIDIVPFQKDSDEL
                     TAYVNSVILNSRVYVPMYGIEQDKIAIKQWQNALPGYEIKGYEFDFEKEPDIIKNRTG
                     YVRTGWGNEDVIHCRTRAIWDENMLYISVKRLEEIVSENDALEVTIQIVDYSKAGLDY
                     ENCRLFYRYYGFQTWESIRLEETTEAEIFFANMIGKSGDMIEYFVQAKSCSGMCETMP
                     PVAPKGTYKVTIK"
     gene            complement(12565..13104)
                     /locus_tag="PC465_003031"
     CDS             complement(12565..13104)
                     /locus_tag="PC465_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2650315.1"
                     /translation="MSLTIQKVTSYFKDLEKFEELNNEAFPDEERMSIQEMLNLVQSK
                     KIEVSALYDKQQFIGFYVLVIENHIGYILFLAISPEQRSKGYGGKALSLMKKQYPNCQ
                     IVLDMETIEDSAPNLQQRILRKQFYLQNGFYETEYLMEYKGLEMEVLCNQKTFQKNEF
                     ETLLKNLKIREISFHLWKK"
     gene            complement(13125..14450)
                     /locus_tag="PC465_003032"
     CDS             complement(13125..14450)
                     /locus_tag="PC465_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009295908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2650316.1"
                     /translation="MIQLSDNFNYKRLLKFTFPTIIMLVISSIYGVVDGYFVSNFVGK
                     TAFTAVNFIMPFLLILGCVGFLFGTGGGALIAKTMGEGKKEEANEQFSLLIVTSAGCG
                     IILAVLGIVTMPWIASAMGADGQLLTDSILYGCVVIIAIPAYILQCEFQCLFATAEKP
                     KLGLYVAIMAGITNIVLDALFITVFKWGLVGAALATAIGQYVGGIIPLLYFSRQNNSL
                     LKFKKPKFDCDVLKKTVANGSSELMTNVSTSVVSMLYNAQLLKYAGEDGVASYGVLLY
                     VALLFQAVFIGYSVGTAPIISYHYGAKNYDELKNLRKRSLIVIICFAVFMFIIGEFLS
                     KPIAFIFVGYDNNLMEMTLRAFMIYSFSFLFSGFGVFGSSFFTALNDGLTSALIAFMR
                     ILVFQVVSVLIFPIFWGVNGIWFSIVGAEILATIMTAFFIIRKQKKYHY"
     gene            complement(14447..15070)
                     /locus_tag="PC465_003033"
     CDS             complement(14447..15070)
                     /locus_tag="PC465_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidylate kinase-like family protein"
                     /protein_id="HDF2650317.1"
                     /translation="MKIITISREFGSGGRELGKQLADILNFDYYDKEIITAIARKKKI
                     DENYVSYILENHGWRNVPLTMCTSFTNILSMQSMKTDLLIEQSNVINQIASTGKDCVI
                     VGRNADILLKKYQPFNVFVCANMNFKIQRCIEKKLNNEHISKKELERKIREIDKNRAR
                     SREFFTSSLWGNQTSYHIIVNTSEWNIKHLSYAIANFSEYWFRRYEQ"
     gene            15162..15971
                     /locus_tag="PC465_003034"
     CDS             15162..15971
                     /locus_tag="PC465_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2650318.1"
                     /translation="MIKKLYKTSEFAELCGVKKHTLYHYDEIELLKPSITHENGYRYY
                     TIDQFEKFNIISVLKKAGTPLEEIKQYLNDLDTNTFLNVLHRKLMDLQEEVKKIEKMC
                     SMLRNVISTMEIHLNVNTEKIEIVNCEEEYLIATKIPEAVLTDEKTMLQGIGNHLQYC
                     LLHDYNFHVGEIVLEKNIKQGIFRESYYYSLIKNKVDDERLFIKPKGNYAVMYHQGSY
                     DSLYKTYQNMKNQLEEQGYHIVGNIYEEDLIDYLSEHNAENYIQKISMQVI"
     gene            16405..16767
                     /locus_tag="PC465_003035"
     CDS             16405..16767
                     /locus_tag="PC465_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2650319.1"
                     /translation="MEIDYKAIGQRIKIARIKKGITQESVANIINMTPSHMSNVETGK
                     TKVSLPTLIAIANALSVSVDTLLCDNVLSSKVIFEKEAKDIFSDCDEYEIRSLVELLK
                     SAKTVIRKDREIRKQFEK"
     gene            complement(17117..17674)
                     /locus_tag="PC465_003036"
     CDS             complement(17117..17674)
                     /locus_tag="PC465_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2650320.1"
                     /translation="MRVSREIVIQATSDIVNKDGLNKVSLKVIAEKLGIRTPSLYNHI
                     ESLDDLLLEVAHKGMREMNSQMIKAAIGNFGDTAIKCISIAYFNFIISNPGVYETIQW
                     ATWHGNNETLEIFDEYKSLLEKLILSCNLNTKNTGEVLNLIMSVLHGYSTLQLGKSLL
                     SKEEAIKGLVDSIDTVLLGIHKKYD"
     gene            17932..18630
                     /locus_tag="PC465_003037"
     CDS             17932..18630
                     /locus_tag="PC465_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2650321.1"
                     /translation="MEKKYFEIHGVPSILWGNPSSKLYIYIHGQCGNKEEAEAFANIA
                     VPHECQVLSVDLPEHGERKREKNSFNPWHVVPELISIMEYAKCHWNQISLYANSIGAW
                     FSMLSFEKENLRECIFVSPILDMQQLISNMMLWANVSEEQLKHELIIPTSFGHTLSWE
                     YLQYVKQHPITQWNVPAKILYGKHDELTEIGVVEKFVEKFNCNLTIIENGKHWFNTPQ
                     ELNSLYEWLNTLVK"
BASE COUNT         6445 a         3122 c         2200 g         6865 t
ORIGIN      
        1 ttattagttt gacattagca taaatgccta ttagaataat gttaaactat attctttcta
       61 ctgattttat taaaaaatac caatatacaa aagattatac aaggagaaag ttcaaatatg
      121 gaattagaaa ttacagaaaa aatagaaaaa caagatgaag atactatttt tcaaggatta
      181 ttaaaatata atcttgctag acttgaagat aaaaacccag tggatttagg aatatatatt
      241 cgagataaag caggtaaaat tgttgcaggt tttataggtg ttactcatgg taattggctt
      301 tctataaaat acttatgggt tagtgagaag cttagatata aaggtactgg aagtcagctt
      361 ttatataagg ctgaaaaaat tgctaaagaa cgaggttgta aatatgtttt tttagataca
      421 ttcagttttc aagcacctaa attttatgag aaatttggat accataaagt attttcactt
      481 gaaaattatc ctctaactgg aaagagatat tattatagaa aaatactata ataataaaaa
      541 tcatatttca tatttttaac ttaaaacttc tgttcttcgt ctacagactt tatattttta
      601 tatcattatt aatactaaaa tagtatttta ctatacatac aaaattattt gaaagttcaa
      661 aaattataag tataaaagct aatcttagct taaataaaaa ttatattttt aggaggtaaa
      721 tatgttagga aaaaaatgta tggattatct acaaacatta ggaaaaataa gttcaacaac
      781 aaatggtctt acaagactta tcttgactca agaacataaa aaatctattg atttaattag
      841 ttcatggatg gaaggtttaa atcttgatat tgaaattgat gacattggaa acgttatagg
      901 tacatataaa tcaagctttc caaatgctcc cacattagta gttgcatctc atcaagatag
      961 tgtaaagtgt ggaggtatat ttgatggtat gttaggtata atagtgcctc tagttggtct
     1021 tgaagaagca aaacacaata ataggtctta tcctttcaat attaagctaa ttgctttcgc
     1081 tgaagaggaa ggaactagat ttgaaacttc tttaatggga agtaaagttt ttgctggtac
     1141 ttttaaagag gaacttctta aatctgttga tgaaaatgga attacacttg aagaagctgt
     1201 aacaaagttt ggatttaata caaaaaactt aacaaatttg catcctagaa aagatgtaga
     1261 tgcatattta gaatttcata ttgagcaggg tcctgtttta gaaaatgaat ctcttcctgc
     1321 tggaattgta tcaagtatta caggatttaa aagttttaag atatcagtaa atggtaagtc
     1381 tggacatgct ggtacacttc caatgaatat gagacttgat gctggatgtt gtgcctgtga
     1441 atgtgtatta gctatcgaaa aagtagctaa aacgactgct gatttggttg ctactgtagg
     1501 aaagatgaat ttctatccat cttcatcaaa tgtggtacct gaaagagctg aatttacact
     1561 cgatgtacgt tcttgttcac aagaaattct tgataattct gtagaaaaga tatttaatga
     1621 aatatcacat atatgtgaaa atagaaaact taattataca agtgaacttg cttttgaaaa
     1681 tgttcctgta ccatgttcta ataaaataac aaaaatcata gaaaaaagtt ttatagattt
     1741 aaatcttaat cctttttata tttatagtgg tgctggccat gatgctcagg aaatggataa
     1801 tataactgat attggtatgg tatttataag atgcgctggg ggcgtaagtc ataatcctaa
     1861 tgaaagtgtt tctgtagatg acttggatac tgctgtaaaa atatttttaa aaatactaga
     1921 taatcttgat ttaaaataat tcttatataa gaaagtatat taaaatatat aatctaaaaa
     1981 atcactttat atttatatta tataagtgta caatataatc tattataaaa tataatttta
     2041 tgcttttata gatttttatt ttatacataa atatatttat atataaagga gataattttt
     2101 atgaatgaaa aattaattgg tattttggct ggaatgggtc caaggtcaac agcccctttt
     2161 gttgatttaa ttattgatga gtgtcaatct caatatggag caaaatatga tgatgaattt
     2221 ccaaagatga tgatatattc attacctacc ccattttata ttgaccgtcc aataaatcat
     2281 gaacttatga aagaaactat aattgatgga ttacaaaagc ttgaatcaac tggtgtaaat
     2341 tttattgcaa tgccatgcaa ttcagcacat atatacttta aagaattaaa agagtctatt
     2401 aatataccaa tattaaatat tgtagaagaa acagttaaaa aattacctac tatctcacaa
     2461 aaagtaactc ttttttcgac tagttcaact tttgagtcta caatttacca gaatggtata
     2521 atacataatg gacatgaatt tatatttaaa gatgaatggc aaataaaatt aaacaatctt
     2581 attcaaaata taaaaatgga taaagaaaat ccacacaata ttgatatttg gaataaactt
     2641 attgaagatg ttaaaaatga atctatagaa aatatagtaa ttgcttgtac tgatttaaat
     2701 gtagttttag aaaaatcata tccttcaata aatattgttg attcatcaaa atgcttggct
     2761 gaatcagttg tcaataaata tctaaaatta gttaaataaa tttttcatgc actatattat
     2821 aaaaaatata tgttataagt ttattttaaa tagtatagac ttataacata tatcatagtt
     2881 tcttgacaat atagaaatta accatgtatt tcattatatt aataaaaagg ataccaaaaa
     2941 tggtatcctt cataaatatt tatatgttta tttataaaaa taatcatata tttattactt
     3001 tactacacct aaacaatatt attcaagtgt attcatagag ttagaaaatt cttgtcctgc
     3061 tgtaacaaga ttagataaca atacatcagc tactgcatca tttactgaac ttattatcca
     3121 tttattatcc tttttagaac attcaaactc tacatttttt gtaacataag tctctttaac
     3181 gcttttttgt ttttctttca taattgatac taacatttca gttgttttct catcagttaa
     3241 gtcttgtcct gaaaaactca taccaatcat ctttgtaaat gcctcagcta ctatttcttg
     3301 aagtaatggt gttgaatcta taaatttaca ttctactttg attgtagcct tatcaccttt
     3361 aacctcgctg tcttttattg tatatgtgat tttagatgca ttctgtttta gataatctaa
     3421 aacatattgg gcatttgggt cttttgtatc taattccttt aatatatcct tatatttttc
     3481 gtcattattt tccattacct tattcatgcc ttcaaagtca aactttttcg cactgttaaa
     3541 aaaactatca attgtatctt ctggttttgc acttgaacat gctgttaaag atattgctaa
     3601 taaaaaagtt gttaaagcta atatgatttt tttcatatct caaatcctcc ctcttaattt
     3661 gttgatacat aagttatttt aacatataat gagagttttt gaataatata tttaaaatat
     3721 tttataaatt ttcattaaag taaagtctat attaaaacat atctatatta aattattgtt
     3781 catatttaca tcagtcatag tagaaaccat aacagctttt attgtatgca ttctattttc
     3841 agcttcttca aatacttttg aatattttga attaaatacc tcgtttgtaa cctctaattc
     3901 tgataatccg aacttttcat aaatctcctg agcaacctta gtttctaaat catgaaatgc
     3961 tggaagacag tgtaaaaata taacattttc attttcagtt ttctttatca tatccatatt
     4021 tacttgataa tctttaagtt gatttattct tgcttcatat tgctcctctt ctcccataga
     4081 aacccataca tctgtatata taacatctgc acctttaaca tcatcaatat tttcagtcaa
     4141 cattatatct cctttggatt tcttggctat ttccttcatt tccttaacca attcttcatt
     4201 tggccaaagt tccttaggtg ctagtgctac gaaatgtatt cccattttag cacatcctat
     4261 catcagtgag tttcccatat tatttctagc atcaccaaca tatacaaatt taactttatt
     4321 caaatcttta tctacatttt caattactgt taaaaaatct gccagtattt gtgttggatg
     4381 atattcatct gtaagtccat tccaaacagg tacaccagaa tattttgcta gactttcaac
     4441 tgtttcttgt ttaaagcctc taaattctat tccatcatag aatcttccta gaacttttgc
     4501 tgtatctgat acagactctt ttttacccat atgacaatca tttggaccta gataagttac
     4561 atgtgctcct tcatcatgag ctgctacttc aaatgaacat ctagttcttg ttgatgtttt
     4621 ctcaaataat aaagctatat tttttccttg tagcaaatcg ccttttatac caactttttt
     4681 cttagttttt aaataacttg ataaagttaa taaatatcta atctcttctt ttgtaaaatc
     4741 ctttaatgtc aaaaaactct taccttttaa acttatatta ttcatattaa ttcgcccctt
     4801 cttataaact ttttaaattc aattaaactt gttagcactt tactttttta tttacttcta
     4861 atttttatct ttaatcaact atttcttgaa tatttagtta atttctagta atatatcttt
     4921 taggatttca agagcctcat ctatttcctt ataactgatt gttaatggtg gtaaaaatct
     4981 caatacattt tttccagcag tcaaaataag caatcctttt tttctagctt tctcttctat
     5041 aatactagat tcaatattag tttcaattcc tatcattaga ccaatacctt ttgtctttaa
     5101 tacaactttg ttattaaaac tttcaataga ttttcttata taatttcctt tttctaatac
     5161 ttcattataa aaaccatctt tagatatctc atctaataca actgaagctg ccaccatagc
     5221 taataaatta cctccaaaag ttgtaccttg gtctcctttt cctagtactt ttgaaagttt
     5281 tttatttacc aatactcctc ctactggtat tcctgctccc aacccttttg ctacggtaac
     5341 tatatctggt tttacatcaa aatattcata gccaaaaagt ttaccagttc ttcctatacc
     5401 gcattggact tcatcaaaaa tcactacaat atccttttct tgacatattt ttactatttg
     5461 caaaacataa tctttttcaa gaacattaac tccaccttcg ccttgaatcg cttcaagaat
     5521 tattgcacaa actgtggaat caagattatt ttttaaatct tcaatattat ttctttctat
     5581 atatttaaaa ccttcgggaa gaggataaaa atacttatgg tatttgtcca taccagttgc
     5641 cattaaagac atcattgttc taccatgaaa agagtctttt aaacttatga tagttcctct
     5701 accattacca tatttgtcac tactatactt tcttgctatt ttgaatgctg tttcatttgc
     5761 ttctgttcca gaattacaaa aatatacttt agccattcca cttgaattaa ttattttctc
     5821 tcctgaatac aacactggct cattaaaata taaatttgaa gtatgtaata atttatctac
     5881 ttgctctttt agagcattct ttaaattact attactatac ccaagagaag atactccata
     5941 tccacttgta aaatctatgt atttattgcc attagtatca aaaaaacaac ttccttcacc
     6001 ataatctatg acaaaattgg gttggttata tgtatctata aaatattcat tccattttga
     6061 aattgtattg tcgttattca ttcttattct cccctcttaa acttataatt ttattcattt
     6121 tcttttctta ttaatgtacc tattccacta tcagtaaata gctctgttat tatagaatgt
     6181 ggaactcttc catccaaaat atgtacccta tttactccgt tatttaaggc atctacgcat
     6241 ccctctattt taggtatcat acctccagta attatacctt cttcaaataa tttatcaaca
     6301 tcctctaata taacttctgt tattaatgat ttttcttcat ctggctctct taacaaacca
     6361 ggtacatctg taagaagtat caatttatct gcatttaact ctttagctat agcagaagct
     6421 gctgtgtcac catttatatt ataagtctct ccatcatctc caacacctat agttgcaatt
     6481 actgaaatat aacctgactt tagacaagat tctataagct caacatttac ttttttgatt
     6541 tctcctacaa atccaagttc ataattttta tatgggtcac ataaaatcat attattatct
     6601 attccacaaa gccctactgc ttttccacct tttgtatgta ttttatttac taggtcttta
     6661 ttaacctttc cagcaagtac catttttaca atttccatgg tctcttcatc tgtatatcta
     6721 agaccattta caaatttact ttctatatcc acttttgcta gcatcttatt gatttctgcc
     6781 cctccaccat gtactaaaac tatattgatt ccaacataac tcattaacac aaggtcttcc
     6841 ataacagatt cttttagacc atcttttttc attgcacttc caccatactt aactacaata
     6901 gtctttccct gatgtttttc tatatatggt aaagcttcta taagtgtatt tgctttttct
     6961 atattaatca ttaaagtata tcctcctaat ttctataact tccatttatt cttacataat
     7021 catagcttaa atcacatccc catgcatttc ctctggcatt gcccatattt aaatctacta
     7081 atatacttat ttcgtcatct tcaaggattt tttttgcttt ttcctcatta aaatctaatc
     7141 catttccatt tttacatact tcaatatatc ctttcatact ctcaaaaata atatcaactt
     7201 tttccatatc tatttcttca cctgcataac ctaaagcaca cagtattcta ccccaatttg
     7261 cgtcagctcc aaatacagct gtctttacta atgaagaaga tataactgtt tttgctaatt
     7321 ttactgcatg tgcttcactt aatgctccat ttatatagca ttcaattagt tttgtacatc
     7381 cttctccatc ttttgcaaca agtttagcaa gttctataca gacatatgta agtgcactca
     7441 aaaatacttg ataatgttca tcttttttgt ttattctatc attttttgct tttccatttg
     7501 ctagaatcat taccatatca ttagtacttg tatctccatc tacactaact ctattaaaac
     7561 ttttgtcaac agcaattttt aaagcttctt ttagcaaaac tccatcaata tttgcatctg
     7621 tagttataaa tcctaacgtt gttgccatat taggatgtat cataccagaa ccttttgcca
     7681 tacctccaat agttattttt ttatctccat acattattgc tactgctatt tcttttttta
     7741 taatatcagt tgtcataata gcttctcttg ctccaatatg accttgttta cttagattat
     7801 tcactaattc atccatattt tcttctatta aatctatatt taatggcttt cctataacac
     7861 ctgtagatgc aaccaaaaca tcactttctt taatatttaa tttatcactg gtgaatttag
     7921 ccattttata agcatttata agtccttctt ttccattaaa ggtattagca ttagcactat
     7981 ttactatgat agcttgtgct tttccatttt taatgtgttc ctgtgtaaca taaacaggat
     8041 tgccctttac tttattttga gttactactg ctgctgcatc acataaaaca tctgaataaa
     8101 ccaaagctaa atctcttttt tctttatttt ttctcaagcc acagtgaatc cctgaagcaa
     8161 aaaatccttc tgaaactgta actccaccct ttataatctc catatttatc ctcctaatta
     8221 tatgagttta gtatttttta tttctaaaat gatggtgcaa tattttttaa acctgtattt
     8281 tcttcaatac caaatattat attcatgttt tgtatagctt gacctgccgc tcccttaatc
     8341 atattatcta tagctgaaca gattatcaat gtatctccat tttcatgtaa tgatattaca
     8401 catttatttg agaatctaac attctttaaa gaagctatct tatctaatgg aagaatttct
     8461 ataaattctt taaattcata ataatcagtt aatttcctat gtatatcatt tatagaaata
     8521 ttatcttctt ttgtacaata tatagttgat aagattcccc tatttactgg gattaagttt
     8581 ggtgtaaaaa ctacacttac tttttctttg caggattcac ttaaattttg ttctatttct
     8641 ggagtatgtc tgtgtttccc tattttatat gcagtgatat tttcattaac ctccgtaaag
     8701 tgactactaa tcgataattc tctaccagca cctgtaagac ctgatttaga atcaattatt
     8761 atattattat tttttatcaa tttagaactt agtaatggca tcaatggtaa agaaatacta
     8821 gttggataac atccaggatt tgcaattata tctgcatctt ttatatcttc tttgtatatt
     8881 tcacttaatc catatacagc ttttttatgt aagattttat ctataaaaga tactccatac
     8941 catttactat atacttcttc atcttttatt ctaaaatcag cacctaaatc tataactttc
     9001 tttttcgatt taattgcctt tattacaaac ttttcactaa ctccatgtgg aagggctgta
     9061 aacacaacat cacacatatc tataactttt tcattttcta tacatatcat gttattttta
     9121 tatcctatac ttggatatat atcaactata tcttttccaa catacgaatt tgaacctatc
     9181 gctctcactt cgactttatc atgattcatt aataatctaa tcaactctgc ccctacatat
     9241 ccagttgcac caataatacc aacttttatt ttattcattt tgttccctcc atttttatat
     9301 tcaaatagtc ttaaaatcct atctttccac tttactatat gataatcatt tgataatacg
     9361 tagattaaaa tactctaatt aaaacaaaaa accccttagc attataaata ctaagaggcg
     9421 attttccgcg gtaccactct tattggtaaa attacaataa tcattaaaac tcaaattaaa
     9481 aagtatctac aaaatgtaca tttaaaatta aaaaagcctc ttggtcaaag accaagagac
     9541 gaatatacac ccgcgttacc actctaattg ataagataat cttacccact ctaatctctt
     9601 aaggcgagat tcaccaatta ccatactatt acttctggta atctcctcca aagctctatt
     9661 cacaataaaa ttcgttacta ggcttccacc attcccagct ctctatcaac tagctttatg
     9721 ctactctctt tttcacagga tttcaattta ttttcttatt gttttatatg atagtttatt
     9781 tttttaactt tgtcaatata atttttaaat ttttggaaat attttctata taattaattt
     9841 ccagcatttt gtatctaaat tgagttataa atatctacag taataggaca ccatgaattt
     9901 cctgctgtaa tatattttaa aaaagttctc cctcttgaat caagtcattc aaaagctata
     9961 ccttatgtca aaattatttt tcatccagcg ttttttagaa aaaacacaat tttctccata
    10021 aaagagacat acatacaact attctttcct aatgtaatat atgtatgatt tctttgtcat
    10081 ttaacttttt caaaaacgca attaacaata gaataccgaa caacccaata aatccaaaga
    10141 aatgtaatcc tgttagcata ctggctaagg ccaatacagg atgtaactcc atatgtttac
    10201 caactaattt tggttcaata atattcctga taatagtaat cacaatatat agtagtgcaa
    10261 ttcctaatgc cattgaataa tcccctaaaa ataaactgat aataccccaa ggtattagaa
    10321 tacttccagt tcctaaaaca ggtagtatat ctaaaagagc aatgaataaa gcaattattc
    10381 cagcataaga aatattaata atagcaaaac cgacatataa ttcagaaaaa gtgatagcaa
    10441 aaattaaaag ataagaaaaa ccacatttaa taatggtatc aatagtaaac gcttttgctt
    10501 ctgctaaaag ataactttta tttttaggta tctgtagcac tataaatctc tttatcgttg
    10561 gataatcaat tgctataaaa atagaagcaa cgattgtaat aattgttttc ataaatagta
    10621 atggaacaga cgaaacaata tcagtaatac cagatacgat attatttgaa agagaaacta
    10681 tgaaaacact catttcattc atcaatacag gcatatttgc ttctattaat tcaataaacg
    10741 aaaaattgaa tgaaccagaa aatagttcga cttcttttat aactgtttca gtcaaaggta
    10801 ttaccaattc ctcaaacatg gttggtagga aatgaaaaat ttcctttatt ccatatatta
    10861 gatatgtacc tattacactt actattattc ctgcaattaa aaagaataaa aaaacagata
    10921 tggttgctac aatacctcgc tttattagta atttttcact tatgtataag actggtttat
    10981 tcaataaact tgctattaaa aatgcaaaaa caaaaggaag taatacagaa aacgcatatt
    11041 tccctaataa cattagtaag cctaatatca ctaccaaata acagaaattt attaaaaatc
    11101 tctgcttatt ttggtatgat gtatgatctt gttcattcaa ataaaatgca cctcctactt
    11161 tatagtaact ttatatgtgc cttttggagc aacaggaggc attgtttcac acattccaga
    11221 acaacttttt gcttgcacaa aatattcaat catatcacct gactttccta tcatattggc
    11281 aaaaaatatt tctgcttctg tagtttcttc taacctaata ctttcccatg tttgaaaacc
    11341 atagtatcga taaaacagtc tacaattttc ataatctaag ccagctttac tataatcaac
    11401 tatttgaata gtaacttcta aagcatcatt ctctgaaacg atttcttcta atcttttcac
    11461 ggaaatatag agcatattct catcccaaat tgctcttgtc ctgcaatgaa taacatcttc
    11521 atttccccag ccagttctca catatcctgt acgatttttt ataatatctg gctctttttc
    11581 aaaatcaaac tcatatcctt taatttcata tccaggcaaa gcgttctgcc attgttttat
    11641 tgcaatttta tcctgttcaa ttccatacat tggaacatag acacgactat ttaaaatcac
    11701 agaattaaca taagcagtaa gttcatcact gtccttttga aacggaacaa tatctatacg
    11761 aaagattttg aatggacgcc catatctggt ttctaccttt tttacttctt ctaaaatttt
    11821 ttcatatctt tcatacaaat agtgttcttt tggcgttctg ctcacaagta atgtttcttc
    11881 atcaattatt tttaaataac agtcaatatg ttgtaaacca taatcagcaa aattagaaaa
    11941 tatataatac tcattcattc cagtatctct tgccaccata gaaaaaaatt cttcgtcaga
    12001 aattcctttc gcacgatttt ctgtctgtaa aatgtgcata gacatcaatt tattgaaacc
    12061 atctgacata agatttccgc ctgttagtgc ataaggtaat ttcataaatg gcaaaccaat
    12121 ctgtttcgca atcaactctt gtgattgatc ttctttttgt tcataagagt tagtagttaa
    12181 taggttatgt tcgcaatcaa acatgatttc tggtttattt atggatacaa atggtgttga
    12241 catcttatat tctgcaccag ccaaaaagag ttttccgttt tcatcaaaaa tagggtgcat
    12301 accccaatca cgaacccatg gtgtatcaaa tccctgtgga gcaatgcaga aaatcaaatt
    12361 ttttaaattt ccaccccact tacttaaata atattttgca atttcaattt cctctttatt
    12421 tggtacacac atgtatacag aataattttg cgttaaatct acaatatact tatggggaag
    12481 aaaaggtggc catgcaagca tgacaccttt aatcggttcc cattccccag ctaaacgtct
    12541 tttcatttct aatacctcac tttcttactt tttccacaaa tgaaatgaaa tttctctaat
    12601 tttaagattt ttcaacaatg tttcaaattc atttttttga aaggttttct gattacataa
    12661 aacttccatt tctagtccct tatactccat gagatattct gtttcataaa acccattctg
    12721 aagataaaat tgcttcctta aaattctttg ttgtaaatta ggagcactgt cctctatagt
    12781 ttccatatca agaacaattt gacaattggg atattgtttt ttcataagtg acagtgcttt
    12841 tccaccatat cctttagagc gttgttctgg ggaaattgca agaaataata tatatcctat
    12901 atgattttca atcaccaaaa cataaaaacc aataaattgt tgcttatcat ataaagcaga
    12961 tacttctatt tttttacttt gaactaaatt aagcatttct tgtatagaca tacgttcttc
    13021 atctggaaat gcctcgttat taagttcttc aaatttttct aaatctttaa aatatgaagt
    13081 tactttttgt attgttaagc tcatatagat acctccaaat tgatttaata atgatatttt
    13141 ttctgttttc ttattataaa gaaagccgtc ataatagttg ccaatatttc agcaccaaca
    13201 atagaaaacc atatcccatt tactccccag aatataggga atataagtac tgatacaact
    13261 tgaaatacta aaatacgcat aaaagcaata agcgcagaag ttaaaccgtc atttaatgca
    13321 gtaaagaaac tagaaccaaa aacaccaaaa ccagaaaata aaaaggaaaa agagtaaatc
    13381 ataaatgctc ttaatgtcat ttccattaaa ttattatcgt aacccacaaa aataaaagca
    13441 atcggttttg ataaaaattc gcctattata aacataaata cagcaaaaca aataattaca
    13501 atcaaacttc tttttcttaa attttttaat tcgtcataat tttttgctcc ataatgataa
    13561 ctgattatag gggcagtacc aacagaatac ccaataaaaa cagcttgaaa tagtaacgct
    13621 acataaagaa gaacaccata ggatgcaacg ccatcttcgc cagcatattt tagtaattga
    13681 gcattataca gcatactcac aacagatgtg gaaacattag tcattagttc tgaagaacca
    13741 tttgcaacag tctttttcaa aacatcacaa tcaaatttag gtttcttaaa tttaagcaaa
    13801 ctgttgtttt gtcggctaaa ataaagtaat ggaatgatac caccaacata ttgaccgatt
    13861 gcagttgcca gtgctgcacc taccaatccc catttaaaaa cagtgataaa taatgcgtct
    13921 aaaacaatat ttgtaattcc agccataatt gcaacatata atccaagttt tggcttttct
    13981 gctgttgcaa ataaacactg aaattcgcac tgcaaaatat aggcaggaat agcgataatt
    14041 accacacatc cataaagaat actatctgtc aataattgac catctgctcc catagcagaa
    14101 gcaatccatg gcatagttac tatacctaaa acagctagaa taataccaca accagcagaa
    14161 gtaacaatga gtaacgaaaa ctgttcgttt gcttcttctt tttttccttc acccattgtt
    14221 ttagcaatta aagctccacc acctgttcca aaaagaaagc caacacaccc taagattagc
    14281 aaaaatggca taataaaatt gacagcagta aaagcagttt tccctacaaa atttgaaaca
    14341 aaatatccat caacaacccc ataaatagaa cttattacca gcataataat tgtaggaaat
    14401 gtaaatttta ataagcgttt ataattaaaa ttatctgaca actgtatcat tgttcatacc
    14461 tcctaaacca atactctgaa aagttagcaa ttgcataaga aagatgtttt atattccatt
    14521 cagatgtatt aactataata tgataggaag tttgatttcc ccataaggag ctcgtaaaaa
    14581 attctcttga tcttgctcga tttttatcaa tctctcttat ctttctttct aattcttttt
    14641 ttgaaatatg ttcattgttt aacttttttt caatacagcg ttgtatttta aagttcatat
    14701 ttgcacaaac aaaaacgtta aatggctggt acttctttaa taatatatct gcatttctac
    14761 caacaataac acaatcctta cctgtactgg caatctgatt gataacattt gattgttcta
    14821 ttaacaaatc tgtcttcatg gattgcatag acaaaatatt agtaaaagaa gtacacattg
    14881 ttaaaggaac gtttctccaa ccatgatttt ctaatatgta ggaaacatag ttttcgtcaa
    14941 tttttttctt tctagctata gcagtgataa tttctttatc gtagtagtca aaatttaaaa
    15001 tatcagcaag ttgttttcca agttctcgtc caccacttcc aaactctcgg ctaattgtaa
    15061 taattttcat aatatctttt cctcacattt cattgaatat aaaagctttc tatgttatcc
    15121 taaagtatct ggtaacccta aagtcaatag gagatttaaa aatgattaaa aaattatata
    15181 agacaagtga atttgcagaa ttgtgtgggg taaaaaaaca tacactttac cattatgatg
    15241 aaattgaatt attaaaaccg agtattaccc atgaaaatgg ctatcggtat tatacaattg
    15301 accaatttga aaaatttaat attatttctg tgctaaaaaa agcaggtaca cctttagaag
    15361 aaataaaaca atatctcaat gatttagata cgaatacctt tcttaatgta cttcacagaa
    15421 agctaatgga tcttcaagaa gaagtgaaga agattgaaaa aatgtgttct atgttgagaa
    15481 atgtcatttc aacaatggaa atacatctca atgtaaacac agaaaaaatc gaaattgtaa
    15541 attgtgagga agaatatctg attgcaacta aaattcctga agctgtacta acagatgaaa
    15601 aaacaatgtt acaaggtatt ggaaatcact tacaatattg tttattacat gattataatt
    15661 ttcatgtagg agaaattgtt cttgaaaaaa atataaaaca gggaattttt agagagagct
    15721 attattatag ccttattaaa aataaagtag atgatgagcg cctttttatt aaaccaaagg
    15781 gaaattatgc agttatgtat caccagggga gttatgacag tttatataaa acttatcaaa
    15841 atatgaaaaa tcagttagaa gaacaagggt atcatattgt tggaaatatt tatgaagaag
    15901 atttaattga ttatttatca gaacataacg ccgaaaacta cattcaaaaa atttctatgc
    15961 aggttatttg aaaatataaa aagcgtgtat atctcaaatc acatgagaaa tacacgcctt
    16021 ttttaatatc tcgtattgtc tataataatt tgcttaaaat gtcctttttt atcttctaaa
    16081 gttggtatct tatttccaaa tttttgtaga aattcaggtt cattgctatt atttgtttcc
    16141 tcaatgcaaa ctgcatttcc tcatgaattt cagatacaga aatagccttt tattttcgtt
    16201 aaccatttaa tcagtttttt actatctttt tataaaatct taacatgtag gctttatgcc
    16261 tccatttctt ttgtagttgt cttaaaagta gtgcaaattt ttttcttaaa tatatattat
    16321 ataaattatt catttatata gagtattata ttatgctctg taaatagtta caatatttaa
    16381 aagaatgaaa ggagaacaaa aactatggaa attgattata aagcaatcgg acagcgaatt
    16441 aaaattgcaa gaattaaaaa aggtataaca caagaatccg ttgcaaacat tatcaacatg
    16501 acaccatccc atatgagcaa cgtggaaaca ggaaaaacga aagtcagcct gccaaccttg
    16561 attgcgattg ccaatgcact ttctgtatca gtcgatactc tcttatgtga taatgtactt
    16621 tcttccaaag taatttttga aaaggaagcc aaagatattt tctcagattg tgatgaatat
    16681 gaaatccgtt ctttagttga actgctaaaa tcagcaaaaa ctgtaatccg taaagacaga
    16741 gaaatccgca aacaatttga aaaataaaac cacagcttca aggtataaat tgatatgtgt
    16801 tgttagctaa ggtcttttct ttttttatat aatcattttt atataatcaa ataacctatc
    16861 caataatttt ccaattactg tccttatgaa atatcaattt atactatgat acctgtgtcg
    16921 cttttgtctg attatcaagg aattttacag ctaccttttc attatcaaca acaacagtaa
    16981 aaatagggtt taccaattca gaaagtaaat attcttgaaa tatactattt tcctttcata
    17041 aaaatgataa aattttattt tacatcccac gtaatgaagt gttcaataaa taagttaaaa
    17101 taatttattt acctccttaa tcatattttt tatgaatacc taataacaca gtatcaatag
    17161 aatcgactaa accttttata gcttcttctt tactcaaaag tgatttccca agttgcaaag
    17221 tcgaataacc atgaagtaca ctcattatta agtttaatac ttcacctgta ttctttgtat
    17281 ttagattaca agaaagaata agtttttcta ataaggattt atattcatca aagatttcta
    17341 atgtttcatt atttccatgc caagtagccc actgaattgt ttcataaaca ccaggattag
    17401 aaattataaa attaaagtat gctatactta tacactttat agctgtatct ccaaaatttc
    17461 caatagccgc ctttatcatt tgactattca tctctctcat tcctttatga gctacttcaa
    17521 gtaataaatc atctagactt tctatatgat tgtacaaaga tggtgtacgt attcctagct
    17581 tttctgcaat aacttttaaa gaaactttgt taagcccatc tttattaact atatctgatg
    17641 tagcttgtat aactatttct ctactaacac gcatgatttt ccctctttca tttaaaatta
    17701 attactttat tagtttagct aatctaatta gtttcgtcaa ttattgtaat ttataaaatt
    17761 ctttatacta ttataaaatc ttgacagttt aattataatt taatataata ctaattgaat
    17821 tagttttaat actaatataa ttagtattat attaaattct atattacaac attattttat
    17881 agtttgatta attcaacaat cactaatata tcaaactgaa aggagatttt tatggaaaaa
    17941 aaatatttcg aaattcatgg agttccttca atcctttggg gaaatccttc aagtaaatta
    18001 tatatttaca tacatggaca atgtggcaat aaagaggagg ctgaagcttt tgctaatatt
    18061 gcagttccac atgagtgtca agttttaagt gttgatttgc ctgaacatgg agaacgtaaa
    18121 agagaaaaaa attcatttaa cccatggcat gttgttccag aattaatatc tattatggaa
    18181 tatgcaaagt gccactggaa tcaaatttcg ttatatgcaa atagcattgg agcatggttt
    18241 agtatgttaa gctttgaaaa agagaactta agagagtgta tttttgtatc tccaattcta
    18301 gatatgcaac agctcatttc aaatatgatg ctttgggcaa atgtatcaga agaacagctt
    18361 aaacatgaac taattatccc aacttcattt gggcatactc tttcatggga atatctacaa
    18421 tatgtaaaac aacatcctat cactcaatgg aatgtaccag caaaaatatt atatggtaaa
    18481 catgatgaac ttactgaaat cggtgttgta gagaaatttg tagaaaagtt taattgcaac
    18541 cttactatta tagaaaatgg caaacattgg tttaacacac cacaagaatt aaattcatta
    18601 tatgaatggt taaatacttt agttaaataa aa
//
LOCUS       DAMJXI010000070        18557 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.073, whole genome shotgun sequence.
ACCESSION   DAMJXI010000070 DAMJXI010000000
VERSION     DAMJXI010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18557
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.073"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     regulatory      103..205
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            299..1675
                     /locus_tag="PC465_003038"
     CDS             299..1675
                     /locus_tag="PC465_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDF2650322.1"
                     /translation="MQTTNSSTMQKLFPILTNKNVDMKKEIIAGVTTFLTMAYIIAVN
                     PNILSETGMPAGALVTGTCLAAAFGCILMGVVANLPFALASGMGLNAFFAYTVVLQMG
                     VPWEVALTAVFVEGIIFIVLSVSGVREAVVNAIPKNMKLAVTGGIGIFIALIGLVNSG
                     IVIGDQATLIKMGRFTPAVIITCVGLIIIAVLDKKRVKGSILFGIVVSSLLAWAFAFI
                     NPEYAQKLGIYLPGGLFKFESLAPIAGKIDLGYVLHPTNIGGFLVVVCTFLFVDFFDT
                     VGTLVGVCSKANMLDEKGNVPNVGRALLTDAVATTVGAGLGVSTVTTYVESSTGVIAG
                     GRTGWTAITVGILFLAAMFFSPVFIAIPSCATAPALIYVGYLMLGTVKDIEFDNITEG
                     VPAFVTIACMALTYSIGDGLTLGILTYVFVNIFYNIFGAKKAEDKKHVSVVMIVLAIL
                     FIIKLWLL"
     gene            complement(1789..2934)
                     /locus_tag="PC465_003039"
     CDS             complement(1789..2934)
                     /locus_tag="PC465_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2650323.1"
                     /translation="MNTFEQLKISSTLIDGLKKQDITSPTEVQSLVIGNIIQNKDLLI
                     NSQTGTGKTLAYLLPIFEKIDTSKRETQALILAPTHELVMQITNQVELLAKNAELSVT
                     SLALIGEVNIQKQIKNIKAVKPHIVIGSCGRVLDLIKQKKLKSHNIKTIILDEVDNLL
                     NGKNITCIEDIIRTTLRDRQIIGCSASLTDSTIKICDKLMKEFEIIKTKEKSQINPNI
                     NHSYLLGEIRDKFTFLRKALAATNPKKAIVFVNNEKNIEVLVSKLNYHNYKAIGIFGN
                     MEKEDRKNAINKFKLGKAKILITTDLSARGLDIVDVSHVFNLDFPKSKNEYLHRCGRT
                     ARGNRSGNTISIITKKELDIIKDLQKEFNIVITPKTLQNGELIDIIK"
     gene            3187..3894
                     /locus_tag="PC465_003040"
     CDS             3187..3894
                     /locus_tag="PC465_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2650324.1"
                     /translation="MLKVINVSKSYKNKKVVSSVSFDVNDGELFGFIGHNGAGKTTTI
                     KAIVGIHDFEEGEVLINSKSIKKQPVECKKEMAYIPDNPDLYESLTGIQYLNFIADIF
                     EVAKDKREELIKYYSNKFELNKALGDLISSYSHGMKQKLAIISALIHSPKILILDEPF
                     VGLDPKASFILKEIMREFCDKGGCIFFSTHVLEVAEKICDKIAIIKDGNIIAYGTTEE
                     VKGSNSLESIFMELIEK"
     gene            3941..5536
                     /locus_tag="PC465_003041"
     CDS             3941..5536
                     /locus_tag="PC465_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2650325.1"
                     /translation="MSNLSILIKNNIINEFKLNALKKADGREKQKIMGMMLSVVIIAG
                     LLIFYVTSLSLSLVDILKQINQLEMLLIFGFGLSTLTTIVTSLYKTSSYLFQAKDLDL
                     LTSLPIKESTVLASKILMLVGANYLFSSICMIIPAVVYFLNSDVSITYFPYLILLFLA
                     LPLLPIVASSIIFLFIGQISSRIKYKNLVLIIGSIILMLLYTLLMSRLNSMSVEMLKN
                     SVSISETIRKVYPPIYYFVDALKTGSIVSFLAFIAISIIPFFMFVTLFAKKFKDINAK
                     MSEGYKSKNYEFKGQKTSRPSKALLKKEFKRYTSSFIYFLNSSAGLLFLIVGTILILL
                     FGADKVGELLKLNIDFNLIKIQLLGVFFFIIVMNCTTYCSISLEGKNLWILKSSPIDE
                     REIFWSKVLMNFLLNAPLSILCLILVSIRLDFEIQFIIVSICLIVSFSMFVALMGLLS
                     NLLYPNLDWKNEVAVVKRSASMIVTMLVSLAYVIILGGIYVLLGISFLNIYIILASIL
                     TLILDFMIWRIISTKGVRIFKNL"
     gene            5639..6721
                     /locus_tag="PC465_003042"
     CDS             5639..6721
                     /locus_tag="PC465_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDF2650326.1"
                     /translation="MRKLSKREKDFIQYGFLLFLICITTYLVLTTLDIKLIPKIIRLV
                     NKTYIFLGILTIIVYMIIESIVTHLIINAVQKTKVKFIGIKMATMGFYYNLVTPFASG
                     SQPMQIYALTKYDVSLSKSVAIVTNKTVVFQSTVTVFCGILILLNKSLLMEQVHSVKV
                     LITFGMIMNVSMLLGGLLIVFSPKQVKMIAEVLINFLSKFKTFKFLDSKRDRINHYID
                     DYNYSIKIFIKNVRILVLSILLTVLQLIAYFSIVYCVYKASNLRGVSYVHIMTLQVFL
                     YMAISPIPTPGNVGANEVTFFTMFSNIIPKELLGYSVLLYSGFVYYFILIVSGLFTFG
                     THYTLNSWKKEDKVNSNLDKVIEKLN"
     gene            6870..7031
                     /locus_tag="PC465_003043"
     CDS             6870..7031
                     /locus_tag="PC465_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III"
                     /protein_id="HDF2650327.1"
                     /translation="MKQDKQNEKQSEISKIKQSNDNKLEIAQELHVSKNIGNMLGYRI
                     DKKKMNRPS"
     gene            7372..8640
                     /locus_tag="PC465_003044"
     CDS             7372..8640
                     /locus_tag="PC465_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDF2650328.1"
                     /translation="MEASIHTIASNNLLIIFAIVSITGIICSKLSEIIKVPDVVLYLL
                     VGILIGPSFLKFIDIRGFQIENQLILTFGSAFILYLGGKEISLKVLRNVKISVFLLAT
                     LGVVISAFIMQQVIGFTFGISAMTALLAGTIIASTDPATLVPIFNQVKIKDRVKQTVI
                     SESAFNDATGAILTSAVLAVILSNKFSLGENIYELGTMVIVGVLVGLITGILLLKLVN
                     DKPYGIFKDFAPIISVISVVVAYELSTKLGGSGYMSCFIVGIITGNKKNFKIWLSQKS
                     YDADFYVAETLGTICRMAIFIILGSQVNLAQLSKYFMPSVITVLVLMFIARPLCVLVC
                     TLVDREAKWSKSEILFMMWVRETGVIPAALCGIISAMKVPGYEVISSVVFMTILITLV
                     IQGSTTKLVAKKLGLLEEEVINISEKVSTF"
     gene            8835..9623
                     /locus_tag="PC465_003045"
     CDS             8835..9623
                     /locus_tag="PC465_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HDF2650329.1"
                     /translation="MFTVMDIVQPDTVEEAYSILNKRKTNQVIGGSAFLRMGKKRIGT
                     GIELSKLNLDYIKEYEDYVEIGSMTTFRTLETSSIIKNNFGRIIEDSVKNIIGVQFRN
                     VVTVGATVFSKYGFSDLIVALLSLDTEVELYNIGRISLEEFLNRDYEKDLLIKIYIKK
                     TNKNASYKSLRNAKSDYPILNVSVSKHMEQFKLCVGARPQKATIAKQASEFLSNNEIN
                     EINIDKAVEIASEELTFGSNMRASREYRKAMSKVLLKRAIMEVI"
     gene            9623..10072
                     /locus_tag="PC465_003046"
     CDS             9623..10072
                     /locus_tag="PC465_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HDF2650330.1"
                     /translation="MLVKININGKKKSVDIEPEEYLVDTLRKVGNLSVKRGCDTGCCG
                     LCTVLIDKKPTLSCATLTLRALDKEITTIEGLENEVKEFSEVLVKEGAEQCGFCSPGF
                     ILTVLAMKDELENPTDDEIKHYLTGNLCRCTGYMGQLRAIKTYLEVK"
     gene            10076..12340
                     /locus_tag="PC465_003047"
     CDS             10076..12340
                     /locus_tag="PC465_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2650331.1"
                     /translation="MNIVGKGIKKIDGMSITTGKPVYTDDLSAKDALVVKILRSPHAY
                     AKIKDIETSKAEMVDGVECVLTYKDVPKSRFTLAGQTYPEPSPYDRLILEDVVRYVGD
                     EVAIVAAIDEKTAIKAMNLIKVKYEVLTPVLDFEEAIGNKTMVHDEDRHCNFDIGMQR
                     EKNIVSHHDYTKGDVEKVLSNCDVVIEETYYTQAQAHAMMETYRAYNYLDHMGRLVVV
                     SSTQIPFHVKRHLSRALEIPASKIRVIKPRIGGGFGGKQTACVEIFSAIVTLKTGKPA
                     KIIYDRKETFNCSTSRHAMRLKVRLGATNDGIIKAIDIKALSDTGAYGEHASTTIGLV
                     GEKTLPMYNKVEATRFIADVVYTNKMPAGALRGYGASQGCFAVESTINMLANKLKMDP
                     TDLRLKNVVTEGETTFAYGKTLNSVDLIKCINKGKELIGWNEKYPCKHLDNGKIRSVG
                     MAITMQGSGIQGLDKSSAEIKLNDCGDYTLMIGSTDMGTGSDTILAQMAAEVLDTSIE
                     NITVISADTDLVPYDPGSYASSTTYVTGMAVVKAAQDLREKIISAGATKLGVEKDEVE
                     FDGIKLTSKKGSTLLFDIAVDSTIGPDTNQLIGLASHGSPVSPPPFIAGFAETEIDTE
                     TGKVDLVNYVAVVDCGTVINKNLAKIQVEGGIVQGIGMALFEEVRYTEKGSMDTNTFM
                     QYKIPARCDIGNVKVDFVETYEPTGPFGAKSVGEVVINTPLPAIQEAVFNGIGVRINT
                     LPITPEKVFMEMNK"
     gene            12480..12791
                     /locus_tag="PC465_003048"
     CDS             12480..12791
                     /locus_tag="PC465_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650332.1"
                     /translation="MAGNLNNMRAVNNFRGDKNILECLVSFEGRSISQRKVRVFFKEK
                     QNQIEIDFAEEEISKLVENVVLNTSYQEMLYDEIEKQLEIDCIGTWMILSKLKDGSRV
                     H"
     gene            13077..13577
                     /locus_tag="PC465_003049"
     CDS             13077..13577
                     /locus_tag="PC465_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HDF2650333.1"
                     /translation="MRKNSINIALTAAITAIYAVLTLSLGFISYGPIQFRVAEIMMLL
                     AFLDKGYIVGLTLGCFLANVIGPYGVPDIIFGTLATFISASMIYITRKLGKQNKSTLV
                     IASLWPTVINSIVVGLMLNVFFGLPLILSMIQVGFGEFVVVTIVGVPFFCFLMKKYKN
                     VINIKF"
     gene            13634..14620
                     /locus_tag="PC465_003050"
     CDS             13634..14620
                     /locus_tag="PC465_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HDF2650334.1"
                     /translation="MSKVKRLTDVWIYINDKQKFTIKELSEEFNLSAKTIQRYLKELN
                     KMGLPIQAEQGRNGGYRVLNNSYIPPVIFTEKEVMIILFALKSLQIYNYKLMEIEINS
                     IMRKVSYERKSSIKVGIENIKRYIGFVANDTNDGDFKSSNVTEFFRASSESLILNIKY
                     KCGNQILEKNVCPIGIYLNKGAWFSPAYDCKSDKIILVHIDNIIDIKRTGESKKIHIN
                     LEEWLHEVYNNLYGNSSTTKKFGEIIYLNVLLTKEGVSKIKDSSWNLDMELNEDGSGI
                     ISTFIKVEDIDCYASILFFIGNNAKVIEPKFLNKLLYDKANELRYFYEENMV"
     gene            14670..15392
                     /locus_tag="PC465_003051"
     CDS             14670..15392
                     /locus_tag="PC465_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HDF2650335.1"
                     /translation="MENFNKNAKIIGIGAEGINIINEVEEKIKANMDIEKININQEIE
                     KEYVRSLLDGVDILFLIYSSEDKHIRDIIKAVSYMSNERRVLSIGMDCSEKENKEDLE
                     LGREFKINNDSIFKFVDLMNIMVESISDSCMINIDITDLKEAIVGDKGIKYSFEEFED
                     TKSYSEIADILFDRMEYIGEEFISKKGIVFVEGSPEFSIMELNDLISNIQSKVEESYE
                     VIFSLYIKENLNGNIRVGLLYN"
     gene            15421..17355
                     /locus_tag="PC465_003052"
     CDS             15421..17355
                     /locus_tag="PC465_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2650336.1"
                     /translation="MSENIRGTEYWLMEEFFYQETDTPQIFREESIIALGFDIKINLK
                     KVFSMGKKSEKYINENCNDKDFIKKFMSIKKGDYFLYKAYQNIEEKVKCNVSIGIVEE
                     DFENGYELSHILGHTLPVKWMHNFDTVSNCKVYISEFYKLNNNDISSYLEIIKSQDKK
                     LLRKRIEESENNKWYLKNYYYKNVDKCVDDEELFIQPINLEQLESLKNIKTDDYILLY
                     NSEKVICENDHTMKSLFGVCQVMEGFDKEKVSALEGGYFFPVRWIEYEKENIDGNAWV
                     IFENNSIVEKYVKRFTNKMALNTILYGPPGTGKTYNTKQMVYNLVSETSLRNRYYTGY
                     LDYKNNVEFCTFHQSYGYEEFIEGLKSDGEGNFKPEDGILKDISIEACYNALKFEKKM
                     SFELEKDSLTLETIKDRKKKLVLENIEYSESFNFEESENYVLIIDEINRGNVSKIFGE
                     LITLLEDDKRLTKSNQTIVKLPYSKEKFSLPPNLYIVGTMNTSDKSIALLDIALRRRF
                     NFEEIMPDYDLLSIVDGIDIRKMLYTINKRIEFLYDRDHVIGQAYLLAVENINDIVVV
                     FRSKIIPLLQEYFYYDSEKVGLILGGIGRNEKDKYIVYKEKLIASELFKNNNASIMES
                     KVNYCIKQNISSEELKNIYE"
     gene            17348..>18557
                     /locus_tag="PC465_003053"
     CDS             17348..>18557
                     /locus_tag="PC465_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HDF2650337.1"
                     /translation="MSKNIYVKETYEWIRVGNGENELTEIEYEKLLKHLENNNDVLKS
                     NIIDIKYKKLRFINYVGIICFENVILEILPKLSLSDNLVKDREILLQMLSICNKIPIT
                     MNEKIRLSLKNYNLLNFFVMYFIESMQTQMKKGIYFEYINKIENLNVMRGKILLSTYA
                     KEKGISPMKIRCEYDEYSENNFLNQVLKKACISILCRINDNSIQGKIKKILSYFQNVD
                     LIYIDRKKLLDYKFYKNNDRFKDCYLLARLLLLNLSMDNSQNNQEAFSILFEINTLYE
                     EYIGILIKSIWDNSFRETYIQDKSKFLLKNEQTGKKNFNLRPDIVLYDLKNEYEIIID
                     TKWKAIEVDSNVFYRSSDIYQMYAYITAYENAKRCILLYPCIQKDKNYSSWKLSESFK
                     GKFIEAKTVRL"
BASE COUNT         7090 a         1833 c         3168 g         6466 t
ORIGIN      
        1 caatatttaa tataatcgaa tattaataca aaatcaatac aatatatacg tatatattga
       61 caaaattaat tatataaatt aaaataatat tcgtaaagaa aaattcatgt tttgtactgt
      121 ataacatata attttgacaa tatgggtcat aagtttctac cggaataccg taaatattct
      181 gactatgtat actattattt agttaattaa atatttaatt aactgaatta tgaaggatac
      241 ggctcagctt atcaactact gtgtcgtttt tttgtaaaat ttaataggag gtgttgttat
      301 gcaaacaaca aacagtagta ctatgcagaa actttttcca attttgacta ataaaaatgt
      361 cgacatgaag aaggaaataa ttgcaggagt aactactttt ttaactatgg cttatataat
      421 agctgtaaat ccaaatattt tatctgagac aggcatgcct gcaggtgcac ttgttacagg
      481 tacttgttta gcagcagcat ttggatgtat tttaatgggt gtagttgcta accttccttt
      541 tgctttagca tcaggtatgg gtcttaatgc attttttgca tatacagtag ttttacaaat
      601 gggtgttcct tgggaagtag ctcttacagc agtatttgta gaaggtatta tttttatagt
      661 attatcagta agtggagttc gtgaggctgt tgtaaatgcg ataccaaaaa atatgaaatt
      721 agctgttaca ggtggtatag gaatatttat tgcacttata ggtctagtta acagtggaat
      781 tgttattgga gaccaagcca ctcttatcaa aatgggtaga tttacaccag cagtaataat
      841 aacttgtgta ggattaataa ttattgctgt attagataaa aaaagagtta aaggttctat
      901 actttttgga atagtagtga gttcattact tgcttgggca tttgctttta taaatccaga
      961 gtatgcacaa aaattaggta tatatttacc tggtggatta tttaaattcg aaagtttagc
     1021 accaatagca ggtaaaatag atttaggata tgtactacat ccaacaaata taggtggttt
     1081 tttagtagta gtttgtacat ttttatttgt tgattttttt gatacagtag gtacattagt
     1141 tggtgtttgt tctaaagcaa acatgttaga tgaaaaaggg aatgttccta atgtaggtag
     1201 agccttactt acagatgcgg ttgcaactac agttggtgca ggacttggag tatctacagt
     1261 tacaacttat gttgagagtt caacaggagt tatcgcaggt ggaagaactg gatggacagc
     1321 aataacagtt ggaattttat tcttagctgc aatgtttttc tctcctgtat ttatagcaat
     1381 tccatcatgt gctacagcac cagctttaat atatgttgga tatttaatgc ttggtacagt
     1441 taaggatata gagtttgata atataactga aggtgttcca gcttttgtta ctattgcttg
     1501 tatggcatta acatatagta taggtgatgg tttaacttta ggtatattaa cttatgtttt
     1561 cgtaaatata ttttataata tatttggagc taaaaaggca gaagacaaaa aacatgtttc
     1621 tgtagtaatg attgttctgg caatattatt tataataaaa ctttggctac tataataggt
     1681 attatttaaa attttaattt aatataaaat aaagggctgt aatttattat caattgtgat
     1741 gataaactac agctcttttg tatttgttgt atttttgtat ttattgtatt atttaataat
     1801 gtctattagt tctccatttt gtaaagtttt aggtgtaatt actatattga actctttttg
     1861 caaatctttt ataatatcta attctttttt tgttattatt gagattgtgt taccacttcg
     1921 atttcctcta gcagttcgac cacatctatg caggtattca tttttacttt ttggaaaatc
     1981 caagttaaaa acatgactta catccacaat atctagtcca cgagcagata aatcagttgt
     2041 aattaaaatc tttgctttac caagtttaaa tttatttatt gcattctttc tatcttcttt
     2101 ttccatattt ccaaaaattc ctattgcttt gtaattatga taatttagtt ttgatactag
     2161 gacttctata tttttttcat tatttacaaa tacaatagct ttttttggat ttgtagctgc
     2221 taatgccttt ctaagaaaag taaatttatc ccttatctca cctaataaat atgagtgatt
     2281 gatgttagga tttatttgtg atttttcctt tgtttttatt atttcaaact ccttcataag
     2341 tttatcacaa atttttatag tgctatcagt aagacttgca gagcatccta taatttgtct
     2401 atctcttaac gttgttctta ttatgtcttc tatacaagtt atattttttc cattcaatag
     2461 attgtccact tcatctaaga taatagtttt tatattatgt gattttagtt tcttttgttt
     2521 tatcaagtct aaaactcttc cacaagagcc aattactatg tgtggtttta ctgcttttat
     2581 attttttatt tgtttttgta tattgacctc cccaattaaa gctaaagaag taacggagag
     2641 ttctgcattt ttagccaata attcaacctg gtttgtaatc tgcattacta attcatgcgt
     2701 aggtgcaagt ataagagctt gtgtttctct ttttgatgta tcaatttttt caaatatagg
     2761 taaaaggtat gctagtgttt ttcctgttcc agtctgtgaa ttaatcaata aatccttatt
     2821 ttgaattata ttccctataa caagtgactg aacttctgtt ggagaagtta tgtcttgttt
     2881 tttgagtcca tctattagag tggaacttat ttttaattgt tcaaatgtat tcatatttta
     2941 ctccttatat tttaataatt atagtcaact attttttatt atacattgtt tattcaaatc
     3001 gaactatata ttcttttata attatgtgta atttgaaagt aaatatcaat tatatttata
     3061 cctttatatt tctgatacct ttgcatttta tagatttcta aaataaacaa ataaaagttg
     3121 taattgtttg atatttgtta tatattatat ataacaaata tcaaaactat aatatggagg
     3181 gaaattatgt taaaagtaat caatgtatct aaatcatata aaaataaaaa agtagtaagt
     3241 agtgtctcat ttgatgtaaa tgatggagag ctttttgggt ttataggaca taatggagca
     3301 ggtaaaacta ctactattaa agcaattgtt ggaatacacg attttgaaga gggagaggta
     3361 ctaataaatt ctaaatctat aaaaaaacag cctgttgaat gtaaaaagga aatggcatat
     3421 atacctgata atccagattt atacgagtca ttaactggta tacaatacct taattttata
     3481 gctgacatat ttgaagttgc caaagataaa agagaagagt taataaaata ttattcaaat
     3541 aagtttgaac tcaataaagc attaggagat ttaatatctt catattcaca tggtatgaaa
     3601 caaaaattag ctataatttc ggctttgata cacagcccaa aaatcttaat tcttgatgaa
     3661 ccttttgtag gtcttgaccc aaaagcttcc tttatattga aggaaattat gagggagttt
     3721 tgtgacaaag gtggttgtat atttttctca acacacgttt tagaagttgc tgaaaaaatt
     3781 tgtgataaga ttgccataat aaaagatgga aatataattg cttatggaac tacagaagaa
     3841 gttaagggaa gtaattcact tgaaagtatt ttcatggaat taatagagaa ataaaatgtt
     3901 ttttatacaa tatagtgtct aaagtgagga atgataaaat atgagcaatc taagtatatt
     3961 aataaaaaat aatataataa atgaatttaa attaaatgcg ttaaaaaaag ctgacggtag
     4021 agaaaaacaa aaaataatgg gaatgatgct ttcagttgtt ataatagcgg gtctattaat
     4081 tttttatgta acgagcttaa gtctctcttt agttgatatc ttaaagcaaa taaatcaact
     4141 ggaaatgcta ctgatatttg gttttggatt atcaacatta acaactattg ttacatcatt
     4201 atataaaacg tcatcatatc tatttcaagc aaaagattta gaccttttga ctagtttacc
     4261 tataaaagaa tctactgtac tagcaagtaa gatattaatg ttggttggag caaactattt
     4321 attttcttca atatgtatga ttatacctgc agtggtttac tttttaaatt ctgatgtaag
     4381 tataacttat ttcccttatt tgatattgct atttttagct ttaccattat taccgatagt
     4441 tgcttcatca ataatttttc tatttatagg gcagatatca tcaagaataa aatacaaaaa
     4501 tttagtatta ataataggta gcattatatt gatgttgctt tataccctac ttatgtcaag
     4561 acttaattct atgtcagttg aaatgctaaa gaatagtgtg tctatttcag agacgattag
     4621 aaaagtatat cctcctatat attattttgt tgatgctctt aaaacaggaa gtatagtttc
     4681 atttttagca tttatagcca tctcaataat accatttttt atgtttgtaa ctctgtttgc
     4741 aaaaaaattt aaagatataa atgctaagat gagtgaagga tataagtcaa aaaattatga
     4801 atttaagggt caaaaaactt caagaccttc aaaagcttta ttaaaaaaag aatttaagag
     4861 atatacttct tcgtttatat actttttaaa ttcatctgca ggtttgttat ttctaatagt
     4921 aggtacaatt ttaatattat tatttggagc agataaagtg ggtgagttac tgaaattgaa
     4981 tatagatttt aatcttataa aaatacaatt attgggagta ttcttcttta taatagtaat
     5041 gaattgtaca acatactgtt caatttctct tgaaggaaaa aatttatgga tactgaaatc
     5101 ttctccaata gatgaaagag aaatattctg gtcaaaagta ttaatgaatt ttttattgaa
     5161 tgccccatta tctattttat gtctaatatt agtatctata agattagact ttgaaattca
     5221 gtttattatt gtatcaatct gtttgattgt aagtttttca atgtttgtag cattgatggg
     5281 attattatca aatttattat acccaaacct tgattggaaa aatgaggtgg ctgtagtaaa
     5341 aagaagtgca agtatgatag ttacaatgtt agtatcatta gcttatgtaa ttatacttgg
     5401 aggtatatat gtattacttg gaatttcgtt tttaaatata tatattattt tggcaagtat
     5461 acttactttg atattagatt ttatgatatg gagaattatt tctactaaag gagtaagaat
     5521 atttaaaaat ttataggtgt atttatgtca aataaagact tatctttttt agtcttgcaa
     5581 ataataggtt aagtagtata ctatgtatag tgatatgaaa aaatttagga gaaaataaat
     5641 gagaaaatta tccaaaagag aaaaagattt tattcaatat ggatttttat tatttttgat
     5701 atgtattact acttatttag tattaactac tttagatata aaactaatac ctaaaattat
     5761 aaggctagta aataagactt atatatttct tggcatattg acaattatag tatatatgat
     5821 aattgaatct attgtaactc atttgataat aaatgcagtt caaaaaacaa aagtaaaatt
     5881 tattggtatt aaaatggcta caatgggatt ttactataac ttagttactc catttgcatc
     5941 tgggagtcaa ccaatgcaaa tatatgcact tacaaaatat gatgtaagcc ttagtaaatc
     6001 agtggctata gttactaata aaactgtagt atttcaaagt acagttactg tattttgtgg
     6061 aattttaatt ttgctaaata agtcattact gatggagcaa gtacattctg tgaaagtctt
     6121 gataactttt ggaatgatta tgaatgtaag tatgttgtta ggtggactac taatagtatt
     6181 tagtccaaaa caagtaaaaa tgatagcaga agttttgatt aattttttat ctaaatttaa
     6241 aacatttaaa tttttagatt caaaacgtga tagaataaat cattatattg atgattataa
     6301 ttattctata aaaatattta ttaaaaatgt aagaatctta gttttaagta tattacttac
     6361 tgtgttacaa ttaatcgcat atttcagtat agtttattgt gtgtataaag cctcaaattt
     6421 aagaggagtt tcatatgtac atataatgac attacaggtc tttttatata tggctatatc
     6481 accaattcca acaccaggaa atgttggagc taatgaggtt acatttttta ctatgttctc
     6541 caatataatt ccaaaagaat tattggggta ctctgtactc ttatatagtg ggtttgtata
     6601 ctattttata ttaatagttt caggtttatt tacatttgga acgcattata cattaaattc
     6661 ttggaaaaag gaagataaag taaattctaa tttagataag gttattgaaa aattaaatta
     6721 ataaaataat tagggaaatt ctatatataa atatggtgtt gaataagcta tattatattg
     6781 agatatttcc cttttttgat taaaattata gaaatttgaa ataataagta ataaacagaa
     6841 aaagtgatat tgttttgaaa ggagaaacta tgaaacaaga taaacaaaat gaaaaacaaa
     6901 gtgagatttc taagataaaa caaagcaatg ataataaact tgaaatagct caagaattac
     6961 atgtaagtaa aaatataggg aatatgcttg gatatagaat agataagaaa aaaatgaata
     7021 gaccaagtta atgaaaatgt tgaaaatggt acattttaaa aaatatatat aatgaaatgt
     7081 tttattgtta aatttaaact tattttaatg gaggaaaaag tcgaaaaata tctaaaaaga
     7141 tatggatata aaaaatatta atatatatat actataaact tgacaaaatc aaccttttaa
     7201 taactagcaa aaaatagcaa aattatataa gcgttattta attgtcaaaa atgaaagcta
     7261 aattgcatgt cctaaaaaaa atgattgata acatttattt gtgtgctata attatatagt
     7321 aaaacaataa gtatattgca taatgtatgc aaatcgggag gagagacgga catggaagca
     7381 tctatacaca caattgccag caataattta ttgataattt ttgctattgt aagtataact
     7441 ggaataattt gtagtaagct tagtgaaata ataaaggttc cagatgtagt gttatattta
     7501 cttgtaggta ttttaatagg accatcattt ttaaaattta tagatattcg tggatttcaa
     7561 atagaaaatc aactaatact tacatttggt tctgcattta ttttatattt aggtggaaaa
     7621 gaaataagtt taaaagtatt gagaaatgtg aagatatctg tattcttatt agctacttta
     7681 ggagttgtga tatctgcttt tataatgcaa caagtaatag gatttacttt tgggataagt
     7741 gcaatgactg ctttactagc aggaactata atagcatcaa cagacccagc cactcttgta
     7801 cctatattta atcaggtaaa gataaaggat agggtaaaac aaactgtaat aagtgaatca
     7861 gcttttaatg atgcaacagg agctatacta acatcagcag tgttggctgt aattttgtca
     7921 aataaatttt cattaggtga aaatatttat gaactgggga caatggttat tgtcggagtt
     7981 ttagttggtt taattacagg aatactgctt ttgaaattag ttaatgataa accttatgga
     8041 atatttaaag attttgcacc aataatatct gttatttcag ttgtagttgc atatgaatta
     8101 tctacaaaat taggtggaag tggatatatg tcttgcttta ttgtaggtat aataactggt
     8161 aacaagaaaa actttaaaat ttggttaagt caaaaatctt atgatgcaga tttttatgtt
     8221 gctgaaactt taggtactat ttgtcgtatg gcaatattta taatattggg tagccaagtt
     8281 aatttggctc agttaagtaa atattttatg ccatctgtaa ttacagtatt agtattaatg
     8341 tttatagcaa gaccactttg cgttttagtt tgtacacttg tagacaggga agcaaaatgg
     8401 agtaaaagtg aaatattatt tatgatgtgg gtaagggaaa caggcgtaat accagcagca
     8461 ctttgtggta ttatttcagc aatgaaagtt cctggatacg aagtgatttc atctgtagta
     8521 ttcatgacta tactaattac attagtaata caaggaagta ctacaaaatt agtagctaaa
     8581 aaacttggat tattagaaga agaagtgata aatataagtg aaaaagtatc aactttttaa
     8641 agttttgctt taaaatagta cctgttaatg gctattttaa tattgtctaa tgatgattat
     8701 tgaaatagtc atttttttat gtataagtaa tttacagaat ttacatatta gacatattta
     8761 ttatcaaaat ttgttgaagc tatgatataa ttagttgtat ttaaaataag aatagcaaat
     8821 aagggaggaa atttatgttt acggttatgg atattgtaca gccagataca gtagaagaag
     8881 cgtactcaat tttaaataaa agaaaaacta accaagtaat tggtggaagt gcttttttaa
     8941 gaatggggaa aaaaagaata ggaacaggaa tagaattatc taaattaaat ttagattata
     9001 taaaagagta tgaagattac gttgagattg gttctatgac tacttttaga acattagaaa
     9061 caagttccat aataaaaaat aattttggaa gaataataga agattcagtt aaaaatataa
     9121 taggagttca gtttagaaat gtagtaacag ttggtgcaac agtattttct aaatatggtt
     9181 tttctgactt gatagtagca ttactttcat tagatacaga agtagaatta tataatattg
     9241 ggagaattag tcttgaagag tttctaaata gagattatga gaaagattta cttattaaga
     9301 tatacataaa gaagacaaat aagaatgctt cttataaatc acttagaaat gcaaagagtg
     9361 attatccaat tctaaatgta tctgtatcaa aacatatgga acaatttaag ttatgtgtag
     9421 gagcaagacc gcagaaagct acgattgcaa aacaagctag tgaatttcta tctaacaatg
     9481 aaatcaatga aattaatata gataaagcag tagaaatagc atcagaagaa ctaacttttg
     9541 gttctaacat gagagcatct agggagtata gaaaagctat gagtaaagta cttttaaaaa
     9601 gagctataat ggaggttatt taatgttagt aaagattaat ataaatggga agaaaaaaag
     9661 tgttgatata gaaccagaag aatatctggt tgatacttta agaaaagttg gtaatttaag
     9721 tgtgaaaaga ggttgtgaca caggctgttg tggtttatgt acagttttaa ttgacaagaa
     9781 acctacatta tcctgtgcaa cactgacatt gagagcttta gataaagaaa taactacaat
     9841 tgaaggttta gaaaatgaag ttaaagaatt tagtgaagtt ttggtaaaag aaggagctga
     9901 gcaatgtggt ttctgttctc ctggctttat acttactgta cttgcaatga aggatgagct
     9961 tgaaaatcct acagatgatg aaataaagca ttatcttaca ggaaatctat gtagatgtac
    10021 agggtatatg ggacagttaa gagctatcaa aacttatctg gaggtaaaat agaacatgaa
    10081 tatagttgga aaaggaatca agaaaataga tggaatgagt atcacaacag gaaagcctgt
    10141 atatacagat gatttatcag caaaagatgc tttggtggta aagatactta gaagtcctca
    10201 cgcttatgca aaaataaaag atatagagac atcaaaggca gaaatggttg atggtgttga
    10261 atgtgtttta acatataaag atgtaccaaa atctcgattt acacttgctg gtcaaacata
    10321 tccagagcca tctccatatg atagattaat tcttgaagat gttgtaagat atgtaggtga
    10381 cgaagtagct atagtggcag ctatagatga aaaaactgca attaaagcaa tgaatcttat
    10441 caaagtaaag tatgaagtac ttacacctgt tttggatttt gaagaggcaa taggaaataa
    10501 aactatggta catgatgaag atagacattg taactttgat ataggtatgc aaagagaaaa
    10561 aaatatagta tcccatcatg attatacaaa aggtgatgta gaaaaagtat taagtaattg
    10621 tgatgtagtg attgaagaaa cttattatac tcaagctcaa gcacatgcaa tgatggagac
    10681 gtatagggca tacaattatt tagaccatat gggaagattg gttgtagtaa gttcaactca
    10741 aataccattt catgtaaaaa gacatttatc tcgtgcacta gaaataccag ctagcaaaat
    10801 tagggttata aaacctagaa ttggtggcgg atttggtggt aaacaaactg catgtgttga
    10861 gattttttct gcaattgtta ctttaaaaac agggaaacca gctaaaataa tttatgatag
    10921 aaaagaaact tttaattgtt caacaagtag acatgcaatg agattaaaag ttagactagg
    10981 tgctacaaat gatggcataa taaaggcaat agatataaaa gcactttctg atacaggagc
    11041 atatggagag catgcttcta caactattgg tttggttgga gaaaaaactt taccaatgta
    11101 taataaagtt gaagcaacaa gatttattgc agatgtggta tatactaata agatgccagc
    11161 aggagcactt agagggtatg gagcatcaca aggatgtttt gctgttgaat caactataaa
    11221 tatgcttgct aataaattaa aaatggaccc aacagattta aggttaaaaa atgtggtaac
    11281 agaaggtgaa actacatttg catatggtaa aactttaaat agtgtcgatt taataaaatg
    11341 tataaataaa ggcaaagaac ttattggatg gaatgaaaaa tatccttgta aacatcttga
    11401 taatggaaaa attagaagtg tgggtatggc aattactatg caaggttctg gtatacaagg
    11461 tcttgataag tcttcagctg aaataaaatt gaatgactgt ggagattata ctcttatgat
    11521 aggttctact gatatgggta caggaagtga tacgatttta gctcaaatgg ctgctgaggt
    11581 tcttgataca agcattgaaa atataacagt tatatcagct gatactgact tagttccata
    11641 tgacccaggt tcatatgctt caagtactac ttatgtaaca ggtatggcag tagttaaggc
    11701 agctcaagac ttaagagaaa aaataatttc tgctggagca actaaactag gtgttgagaa
    11761 ggatgaagta gaatttgatg gtataaaatt aactagtaaa aaaggtagca ctttattatt
    11821 cgatatagca gttgattcta caattggtcc agatactaat caattaatag gtcttgcttc
    11881 tcatggtagc ccagtatctc ctcctccttt tatagcaggt tttgcagaaa ctgaaattga
    11941 cacagaaact ggaaaagttg atttagtaaa ttatgtagct gtagtagatt gtggaacggt
    12001 tataaataaa aatctagcta agatacaagt tgaaggtgga attgttcaag ggattggaat
    12061 ggcattattt gaagaagtta gatacacaga aaaaggaagc atggacacaa atacatttat
    12121 gcaatacaag attccagcta gatgtgatat tggaaatgtt aaagtagatt ttgttgaaac
    12181 ttatgaacca actggaccat ttggtgctaa atctgttgga gaagttgtta taaatacacc
    12241 tttaccagca atacaagaag ctgtgtttaa tggaattggt gtaagaataa atacactccc
    12301 tattacacct gaaaaagttt ttatggaaat gaataaataa ttatttatga aaatttagac
    12361 tagttttaca tgttaaacaa ccagttatgt catacctgtt gaaagatatt taataagtag
    12421 ttattataat attatgaatt ttacttataa aatacaaaat taaataaggg gatgatgttt
    12481 tggctggtaa tctaaataat atgagagcag taaataattt tagaggagat aagaacattt
    12541 tagaatgttt agtcagcttt gagggtcgtt caataagtca gagaaaagta agggtatttt
    12601 ttaaagaaaa acaaaatcaa atagaaattg attttgcaga agaggaaatt tctaaattgg
    12661 ttgaaaatgt tgttttaaat acatcatatc aagaaatgtt atatgatgaa atagagaaac
    12721 aactggaaat tgattgtata ggtacttgga tgatattatc taaattaaaa gatggtagta
    12781 gagttcactg attttaaaat aaattattag agcctaattt taaggctctt ttttgctgtt
    12841 tttaattaac aatagaaaat ttatctttag tttgtatata attttaatat catatattct
    12901 atatatataa aattgaattt gtatgtatta tgttgtataa tataaaatga attaggaaaa
    12961 tagttcgcta aaataatttg tttttataaa attactgttt aagtttatag attttgtata
    13021 aaataaagtt atgttattaa tttttttaga aataaaactt ttactaggag acagatatga
    13081 gaaaaaatag tattaatata gcactaactg cagcaattac agcaatctat gcagttttaa
    13141 cattatcatt gggatttata agttatggac caatacaatt tagggtagca gagattatga
    13201 tgcttttggc atttttagat aaaggatata tagtaggtct tacattaggt tgttttttag
    13261 caaatgtaat aggaccatat ggtgtacctg atataatttt tggaacatta gccacattta
    13321 taagtgcaag tatgatttat attactagaa agttaggtaa acagaataaa agtactttag
    13381 ttatagcttc tttatggcca actgttataa attcgattgt ggttggtcta atgttaaatg
    13441 tattctttgg gcttccatta attctatcta tgatacaagt aggttttgga gaatttgtag
    13501 tagtaacaat tgtaggagta ccatttttct gctttttaat gaaaaaatat aaaaatgtca
    13561 ttaatattaa attttaaata gtgtatagta atttaattaa ttgagagtat tattagtgaa
    13621 aagaggtgtt tatttgtcga aggtaaaaag attgactgat gtttggatat atattaatga
    13681 taagcaaaag tttacaataa aagagttgtc agaagaattt aatctttcag ctaaaacaat
    13741 acaacgatat ttaaaagaat taaataaaat gggacttcca attcaagcag aacaaggtag
    13801 aaatggaggt tatagggtgc taaataatag ctatatacct cctgttatat ttacagaaaa
    13861 agaagttatg attatactat ttgcacttaa gtcacttcag atttataatt ataagttaat
    13921 ggaaatagaa attaattcta taatgagaaa agtaagttat gaacgtaaaa gcagtataaa
    13981 agtaggtata gaaaatatta aaagatacat tggctttgta gctaatgata ctaatgatgg
    14041 agattttaag agtagtaatg taactgagtt ttttagagct tcttcagaat ctctaatttt
    14101 aaatattaag tataagtgtg gtaatcagat tttggaaaaa aacgtatgcc ctataggtat
    14161 atatttaaat aagggagcat ggttttcacc agcatatgat tgtaaaagtg ataaaataat
    14221 attagttcat atagataata taattgatat aaaaagaaca ggagaaagta aaaaaataca
    14281 tataaacttg gaagaatggt tacatgaagt atataacaat ttatatggaa atagttcaac
    14341 tactaaaaaa tttggtgaaa ttatttatct aaatgtatta ttaactaaag aaggtgtttc
    14401 taaaataaag gacagttctt ggaatttaga tatggagcta aatgaagatg gtagtggaat
    14461 aattagtaca ttcataaagg ttgaagatat agattgttat gcttcgattt tattttttat
    14521 tggaaataat gctaaggtta tagagccaaa atttttgaat aagctacttt atgataaggc
    14581 caatgagtta agatattttt atgaagaaaa tatggtataa tatttagaaa tgttgaaatt
    14641 aaataattat taaggagata tacgttataa tggaaaattt taataagaat gctaaaataa
    14701 ttggtattgg agctgaaggt attaatataa taaatgaagt agaagaaaaa ataaaagcaa
    14761 atatggatat agaaaaaata aacataaatc aagagattga aaaagaatat gttagaagtc
    14821 ttttagatgg tgtagatata ttatttttga tatattcatc tgaagataaa catattagag
    14881 atattataaa agctgtttca tatatgtcaa acgaaagaag agttctatct ataggaatgg
    14941 attgttcaga gaaggaaaat aaagaagatt tagagcttgg gagagagttt aaaatcaata
    15001 atgatagtat atttaaattt gttgatttaa tgaatatcat ggtagagtct atttctgatt
    15061 cttgcatgat aaatatagat attactgatt taaaagaagc tattgtagga gataaaggaa
    15121 ttaagtattc ttttgaagag tttgaagata caaagtcata tagcgagata gctgacattt
    15181 tatttgatag gatggaatat attggtgagg aatttataag taagaaagga attgtatttg
    15241 ttgaaggaag tccagaattt tctataatgg aattgaatga tttaataagt aatattcaga
    15301 gcaaggtaga agaaagctat gaagtaatat tttctttata tataaaggaa aatttaaatg
    15361 gaaatattag agtaggctta ttgtataatt agtatatttt agatattaag gagagtgtat
    15421 atgtctgaaa atataagagg tacagagtat tggttaatgg aagaattttt ttatcaggaa
    15481 acagacacac cacagatttt tagagaagaa agcataattg cacttggatt tgatataaaa
    15541 ataaatttaa aaaaagtatt cagtatgggg aaaaaatcag aaaagtatat taatgagaat
    15601 tgtaatgata aagattttat aaaaaagttt atgtcgatta aaaaaggaga ttatttttta
    15661 tataaagcat atcaaaatat agaagaaaaa gttaaatgta atgtgtctat tggcatagtt
    15721 gaagaagatt ttgaaaatgg atatgaatta agtcatattt tagggcatac actaccagta
    15781 aaatggatgc ataattttga tacagtttca aattgtaaag tatatataag tgaattttat
    15841 aaattaaata ataatgatat tagctcatat ttagaaatta ttaagtcaca agataagaaa
    15901 ttattgagaa aaagaataga agaaagtgaa aataataaat ggtatttaaa aaactattat
    15961 tataaaaatg tagataagtg tgtagatgat gaagaattat ttattcagcc cattaatcta
    16021 gaacaattag aaagcctaaa aaatataaag acagatgatt atattttatt gtataatagc
    16081 gagaaagtaa tttgtgaaaa tgaccataca atgaagagtc tatttggcgt atgtcaagtt
    16141 atggaagggt tcgataaaga gaaagtaagt gctttggagg gtggatattt ttttcctgtt
    16201 agatggatag agtatgaaaa ggagaatata gacggaaatg catgggttat atttgaaaat
    16261 aatagtatag ttgaaaagta tgtaaaaaga tttactaata aaatggcatt aaatactata
    16321 ctttatggac caccaggaac tggtaaaaca tacaatacaa aacagatggt ttacaatcta
    16381 gtaagtgaaa ccagtctaag aaacagatac tatacaggtt acttagatta taaaaacaat
    16441 gtagaatttt gtacatttca tcaatcatat ggatatgagg aatttataga gggtcttaag
    16501 tctgatggtg aaggcaattt taagccagaa gatgggatat taaaggatat atctatagaa
    16561 gcatgttata atgcattgaa atttgaaaaa aagatgagct ttgagttgga aaaagatagc
    16621 ttgactttag aaactataaa agacaggaaa aagaaattag tattagaaaa tatagaatat
    16681 agtgagagtt ttaattttga agaatcagaa aactatgttt taataataga tgaaattaat
    16741 agagggaatg tatctaaaat atttggtgag ctaataacat tattggaaga tgataaaaga
    16801 cttactaaat caaatcaaac tattgtcaaa ctaccatatt caaaggaaaa attttctcta
    16861 cctccaaatt tgtatatagt tggaactatg aacacatcag ataaatcaat agcactttta
    16921 gatatagctt taagaagaag gtttaatttt gaagaaatta tgccagatta tgatttattg
    16981 tctattgtag atggtataga tattagaaaa atgctatata caatcaataa aaggatagag
    17041 tttttatatg atagagacca tgttattgga caagcttatc tacttgctgt agaaaatatt
    17101 aatgatatag tagtagtatt tagaagtaaa ataataccac ttcttcaaga gtatttttat
    17161 tatgattcag aaaaagtagg tttgatttta ggaggaattg gaagaaatga aaaagataaa
    17221 tacattgttt ataaagaaaa acttatagct tctgagttat ttaaaaataa taatgcctca
    17281 ataatggaga gtaaagttaa ctattgtata aaacaaaaca tatctagtga ggagctaaaa
    17341 aatatatatg agtaaaaata tatatgttaa ggaaacctat gaatggataa gggtaggtaa
    17401 tggtgaaaat gagcttacag aaattgaata tgaaaaattg cttaagcatc tagagaacaa
    17461 taatgatgta ttaaaaagta atataataga tattaaatac aaaaaactta gatttataaa
    17521 ctatgtaggc atcatatgtt ttgaaaatgt aatacttgaa atacttccta aattgtcatt
    17581 aagtgataat cttgtaaaag atagagagat actattacag atgctttcta tatgtaataa
    17641 aattccaatt acaatgaatg aaaaaataag attgagtttg aaaaattata atctcttaaa
    17701 tttttttgtt atgtatttca ttgagagtat gcaaacacag atgaaaaaag gtatttattt
    17761 tgaatatata aataaaatag agaacttaaa tgttatgagg ggtaaaatat tattaagtac
    17821 atatgcaaaa gaaaaaggca tttctccaat gaaaataaga tgtgaatatg atgagtatag
    17881 tgaaaataat ttcttgaatc aagttcttaa aaaagcatgt atatctattt tatgtagaat
    17941 aaatgacaat tcaattcaag gcaagattaa aaaaatttta agctattttc aaaatgtaga
    18001 tttaatttat atagatagaa aaaaactgtt ggattataaa ttttataaaa acaatgatag
    18061 atttaaagat tgttatttac tagctagact tctactttta aatttgtcta tggataatag
    18121 tcaaaataat caagaggcat tttctatatt atttgaaata aatactttgt atgaagaata
    18181 tataggaatt ttaatcaaaa gtatatggga caattcattt agagaaacat atatacaaga
    18241 taagagtaaa tttcttttga aaaatgaaca aactggtaag aaaaacttta atttaagacc
    18301 ggatatagtt ttatatgact taaaaaatga atatgaaatt ataattgaca ctaaatggaa
    18361 agctattgaa gtagattcaa atgtttttta taggtcaagt gatatatacc agatgtatgc
    18421 atatataaca gcatatgaaa atgcaaaaag atgtatatta ttatatcctt gtattcaaaa
    18481 agataagaat tatagttcct ggaaattatc agaatcattt aagggtaagt ttatagaagc
    18541 aaaaactgtg aggttag
//
LOCUS       DAMJXI010000071        18488 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.074, whole genome shotgun sequence.
ACCESSION   DAMJXI010000071 DAMJXI010000000
VERSION     DAMJXI010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18488
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.074"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            121..1281
                     /locus_tag="PC465_003054"
     CDS             121..1281
                     /locus_tag="PC465_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HDF2650338.1"
                     /translation="MIETGFVYCSFLVVFVGVIFFMVDKLKWKVFDVINPMLLIYLGS
                     AILGSFGLFAQNEDVGTYQNIITVNFLPLMLVFLLIQCDLRKILKMGPKMLLSFFCAT
                     FTFMLGFVIAFIIFKNSMGADSWKILGAASGSWIGGSSNMIAAANALGVAEEGLSYAI
                     LMGSIGYTVWMSVCLMSVKFGPKFNKWTKCDTSFIDEVTSKLEKENKDNTAPTFVELM
                     ILLSVGFGVASFAQIVSKILPTSGILNETMWVVLVASTVSILLGMTKISKLKGSTLVG
                     NVFMYLLLAATGSKANFFGLSEAPVYIMFGLVVVLVHAISFIGLAKLFKLDLFTCEVG
                     SIANIGGVTTAPMIAGVHNPVLIPVGVLMGLLGNIIGTYCALMVTQILHMLA"
     gene            1623..1784
                     /locus_tag="PC465_003055"
     CDS             1623..1784
                     /locus_tag="PC465_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650339.1"
                     /translation="MIIPSRRIQDITLTNLKNGEVTLIELDEIYKKMGFLFVVSEGKL
                     KKIKKENHH"
     gene            1977..2606
                     /locus_tag="PC465_003056"
     CDS             1977..2606
                     /locus_tag="PC465_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HDF2650340.1"
                     /translation="MKIVTYNIHKCMDSNNRLTLTKMGLYLKQLDCDVICLQEVLYPQ
                     FLALKAVLNMDGVFATNVKKVNMIYGICTFTTSKMLNSNHFFLTSKKEQRGALCITID
                     AYGRIINVINTHLGLDRQERAKQLDEIIDYRNRLVGIVILCGDFNEKNVFLSMFNDMA
                     ISLNKSYLPTFEKSNSRIDYIFVNKNTELKGYTVEKIYLSDHYPVIGYI"
     gene            2845..4104
                     /locus_tag="PC465_003057"
     CDS             2845..4104
                     /locus_tag="PC465_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HDF2650341.1"
                     /translation="MGRRTTRVSRLGKEKKRSVLIVLAALVLIMGGFTYFFNSKFLYN
                     GKIAKNVYIEGVNVSDMTKAEALKAITDKYTPEDLNLAYDGKKYTISPKDIDLKYDTE
                     DVVKDAYESTKKGSYFQNLKKYIDIRVNKANMKIKAEYDEAKLSSKVSSIADSINVKM
                     KNASISVGSGGLSYTDSVVGREFDLAANKESIYNMIKNKEHKTLELKVNLQKPDITTE
                     QVKTVNSVIGQYSTTYSQAVEGRSYNVGLSARKTSDVLLMPGEEFSYNKLTGPSNKAN
                     GYKDAPVIVYGKLEQSAGGGVCQTSSTVYNAALLSGMEITQVTNHSSASTYVPKGRDA
                     TVSDGGLNLKFKNPYKHPVYIKNYAGGGSVSSVIYGNSGDKPNISIEVKQTGQNKYST
                     YRIFKDSSGKVIKKEHISNSSYKELKK"
     gene            4363..5358
                     /locus_tag="PC465_003058"
     CDS             4363..5358
                     /locus_tag="PC465_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HDF2650342.1"
                     /translation="MYEEVTWLNFIGNRYEVVNSDDVLEINKIYKARDVFYRKNVLIK
                     VIKHNNYICEDFVSNLIDESTALDEINSPYILKIIDVGIHCTEETTLYYVVSEDFNGI
                     GLDELILGNYLHLEAIVNIMIQVLKALEMIHRNHSYHGSLKSSSIIVDTEYNIKICDF
                     GITKANNGVNTRSYGNRRYLCPHQLCINYTDKESDFFATGLILFESIFKKLPFGESNS
                     EEKMLQSIDKGLDWNSIKAINGNTELINVIKRLLGRNNKYTRANDIIIDLSKVMYEKA
                     YIEVEDEKEEEQKQDKVIQVKKEYKSKMRKKLHKKLVVAGLAIVMISMIIISSII"
     gene            5604..6671
                     /locus_tag="PC465_003059"
     CDS             5604..6671
                     /locus_tag="PC465_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HDF2650343.1"
                     /translation="MSNIKIIASNKCWIEDIARKQLEDISKLNGILRVVGLPDLHAGK
                     IPVGLAVETKNIIYPHIIGNDIGCGMTLFKTGVLKKKFKKDKWIKSLSKIKDLSDIEI
                     KNTYKEECPILNLGTIGSGNHFVEIQCISEIYNKEQFEQLKFSSDDIMMLVHCGSRNY
                     GEDILKKFYDKDGLEVESEKAIDYIKKHDNALMWAERNREAISKKIMQSIGTSGDVET
                     IFSINHNFVEKREDKFIHRKGAVSSERGAVIIPGSRGSLSYIVMPTENTEISLYSLSH
                     GAGRKWSRSVCKSRLKSKYSKDTIKQTKFKSQIICNDVNLLFQEAPEAYKNIEQIIES
                     LIEYELIQVVATMKPLITYKG"
     gene            7205..9115
                     /locus_tag="PC465_003060"
     CDS             7205..9115
                     /locus_tag="PC465_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HDF2650344.1"
                     /translation="MNSNTFERLQLNEVKELIKIHCVSSLGKNLIDKLTPSGNIGVVR
                     RKLAENKEARKIIENSNHIPLEGLFNAGSTIDKIEKGMIIEPVELVNIEDFLRGCRKM
                     KAFMLEKEFYSPTLSSYALNITECKSIEDEINYCIKSNKVDSNASKELKKIRRNIEIT
                     EGKIKDRLNKFITSTVNKKYIQEFIISKRNDRYVIPIKSSYKNEVNGTILDTSSKGNT
                     VFIEPISVSNLSTELTMLKADETIEEYKILSYLTELIFEKISQIKLNIEILSEYDMVF
                     AKAKYSQKIKGITPKINNNGYIKIIKGKHPLLTGDAVPLDFEIGKNYRSLIITGPNAG
                     GKTVTLKTVGLLTLMVQCGFDISAKEGSEFSVFEKVFVDIGDNQSIENALSTFSSHIK
                     NIAEIMSLSNNSTLVLFDEIGSGTEPNEGAGLAISLLEEFYKMGCITIASTHYGEIKK
                     FATLHPEFENAGMMFDKETLEPLYKLTIGKSEDSNALFISKKMGIKNRVLDRAKEYVI
                     DRNYNLDLVKRSKLQSNIEDKNSSEVILNYTDYNVGDKVKLLDEDDFGIVYKPMDKFN
                     NVEVLFNDNFISVNIKRLQLSIKASELYPEGYDLDVLFTSFKERKLEKDIQRGSKKAL
                     KKIQKEIRENRK"
     gene            complement(9178..9801)
                     /gene="ytaF"
                     /locus_tag="PC465_003061"
     CDS             complement(9178..9801)
                     /gene="ytaF"
                     /locus_tag="PC465_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation membrane protein YtaF"
                     /protein_id="HDF2650345.1"
                     /translation="MIESILLVTSLCIDAFVTSFGYGVNKVKVPLYSNIIISVVCSAI
                     LAISLFAGTIVRDFLPQNITMLICFFILFLLGSARLIESFFKSYFKKKSIHSKNYNFN
                     MLDLKLNFNVSIEPDVLDTSKSKVLKSAEAFTLALALSLDGLAIGFGSGLVGVNYIQV
                     ILFSLISNIIAVLLGCLLGNMFVKNVNLNLSWLSGLILLVIGFMKIC"
     gene            9989..10633
                     /locus_tag="PC465_003062"
     CDS             9989..10633
                     /locus_tag="PC465_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2650346.1"
                     /translation="MEQNNKVGNFGDLLKILLDEKELSMGELSKKSGIDKSTISRIAN
                     NKQKPNINHLEKMAIHLNINLEELLKASGYEFRNSNNQIFNADSDFSNFDDILGFANL
                     INDKNFNGNIEKELSKCKLYVQTDEGKKLLFDNFNKKIDSIEKQGQFTDRLRQMYADF
                     CTDGLTIKKYLLIGSMLLYFVISTDVIPDFVFPIGFMDDLVALNIVTKLLKNDK"
     gene            10847..11905
                     /locus_tag="PC465_003063"
     CDS             10847..11905
                     /locus_tag="PC465_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HDF2650347.1"
                     /translation="MNCKWISKIDERKKCHREADSSGYCIFHKENKSDEEIQLMMDTL
                     HKEEISEFNGFVFENEFNAEEILTYNYKILDFSESIFKQKANFKKYIFKKNIIFNYTE
                     FRDKVLFNGCVFLENCDFNRTIFSKHYINDRIFEKVKFKGPDLVVNKVENFPRMDGII
                     FSMCTKFVLKNVEYGKSEYEHGKINYRIARNQATKIGEYEMIGFYYYKERIYSSKIMK
                     RSNYPTFSDYLVEKFFDQIARYTTGYGEKPWNILLVIIAIISVFALLYLFVGIESSNS
                     TLVALDINNIGDYSLSEIFKMYMDLWYFSMATFSTVGYGDMVATSLIGKALAGIEVFF
                     GVTIGAIWASVIIKRMIR"
     gene            12009..13193
                     /locus_tag="PC465_003064"
     CDS             12009..13193
                     /locus_tag="PC465_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF2650348.1"
                     /translation="MKNALKKIISLAMILVFIIPNYSYADDKSVDKYSKTSILIDQET
                     GRVLYSKEPDMKVPLASLSKMMTFLLAIEAIENKEVKETDKVKIDKSIASVKGSSYKL
                     KDGEEVPLIELMRGLMIVSGNDAAIAIAKHICKTKEAFVDRMNKKAKEIGMSNTHFLN
                     PNGLPIYDLSNPKKPAKENISTAKDIAILGKYMFDHYEKQVTAITDMETYTNSDRSFE
                     KSNTNALLRIIPEVDGIKTGYTGNAGYCLSFSMVVNKNDKNEKKRRVIGVVLGTNHKN
                     KRTSASLALLKYGKENFNMKKVIDKDSFIGKKYIKGMKELEVTLKAKDELYTILKGDE
                     SIKSEVKIKNIEYPVKKGDTMGIIKYYTNSGDLLGSVDIVSNNSIDNVSLKTKLKMKF
                     AN"
     gene            13400..14113
                     /gene="rpsB"
                     /locus_tag="PC465_003065"
     CDS             13400..14113
                     /gene="rpsB"
                     /locus_tag="PC465_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HDF2650349.1"
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQ
                     KTVKKVEEAYKFTKEVAETGKPILFVGTKKQAQDAIKDEAERCGMYFVNERWLGGMLT
                     NHKTIKTRINKLRELEKMEEEGVFNVLPKKEVIKLRAEKEKLEKYLGGIKDMPELPGA
                     MFVVDPRKENIAIQEAHRLGIPVVGIVDTNCDPEQLDFAIPGNDDAIRAVKLITGAMA
                     TAVIEGRQGAEEEVAEDQE"
     gene            14192..15103
                     /locus_tag="PC465_003066"
     CDS             14192..15103
                     /locus_tag="PC465_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HDF2650350.1"
                     /translation="MANITAQMVKELRESTGAGMMDCKKALQEAEGNMEKAVDLLREK
                     GLSKAAKKAGRVAAEGLVAIEMNDDNTVASMVEVNSETDFVAKNEDFKVFVKDAACMA
                     LATDKEDIASLLGETHKEGITLQEVLNNRVAKIGEKLDFRRFAKVVTNGQVAGYIHGG
                     GKIGVLVEMETEARDAKVLELGKDVAMQVAAMNPKYVSRDEVDAEYIAHETEVLTQQA
                     LNEGKPANIVEKMVKGRLEKELKEVCLLEQTFVKNPDITVKQLVADVAKAVGSDIKVV
                     KVVRFEVGEGIQKREENFAEEVAKQLK"
     gene            15188..15892
                     /locus_tag="PC465_003067"
     CDS             15188..15892
                     /locus_tag="PC465_003067"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HDF2650351.1"
                     /translation="MDKPMYKRVLLKLSGEALAGERGFGINNDVVNDIAIAIKKIQEI
                     GVEVAVVVGGGNFWRGRTSEGMDRTTADYIGMLATVMNAMALQDALENIDVATRVQTA
                     IDMRQIAEPYIRRRAVRHLEKERVVIFGAGTGNPYFTTDTTAALRAAEMEAEVILLAK
                     NVDAVYDKDPKVHADAKKFTELSYMEVIQKELKVMDSTATSLCMDNKIPIKVFELTTE
                     NIIRAVKGENIGTTVK"
     gene            15918..16475
                     /gene="frr"
                     /locus_tag="PC465_003068"
     CDS             15918..16475
                     /gene="frr"
                     /locus_tag="PC465_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HDF2650352.1"
                     /translation="MKLEIHKQLEEKMNGTIDALKFEFGTIRAGRANAQMLDKIRVDY
                     YGTPTPINQIGAISVPEPRILMISPWDKSAMHEIEKAIANSDLGLNPSNDGEVIRLSV
                     PALTEERRKELAKKASKAAEEFKVRIRNERRDANEKIKKMEKGGELTEDELKKAQDEV
                     QKMTDKFIKEIDTLLSKKEKDIMEV"
     gene            16478..16681
                     /locus_tag="PC465_003069"
     CDS             16478..16681
                     /locus_tag="PC465_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650353.1"
                     /translation="MKKYYNLLGLHVDEVKQYFDEQNINYTVKSIEGKKDKEKLVVPR
                     VIKISEIGDSVELIITYFSDSLV"
     gene            16710..17444
                     /locus_tag="PC465_003070"
     CDS             16710..17444
                     /locus_tag="PC465_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HDF2650354.1"
                     /translation="MNNNIIYDIDLNNIPTHIAIIMDGNGRWAKARFLPRTAGHKAGV
                     ETIRDIVKECSKLGVKHLTLYAFSTENWKRPKLEVDTLMNLLSTYLRNEIAELHQNNV
                     KVTAIGDISALPKTCIRELNSAKELTKNNTGVNLNLALNYGSRADIKNALIDIVKNCE
                     SGKIDINNIDEDIIKNYLSTKSIPDPDLVIRTSGEQRLSNFLLWEVAYSEFYFTDIHW
                     PDFKKEELQKAIYVYQRRDRRFGGLK"
     gene            17457..18236
                     /locus_tag="PC465_003071"
     CDS             17457..18236
                     /locus_tag="PC465_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HDF2650355.1"
                     /translation="MLTRIIASLALVPLFLFVVYGGIPLYIAETAIVYIALHEFYKAF
                     KIKDVHPIFIIGYLFSIYLAVKNIFNLPLEYTYAVIFILFLASIIYMLMGKNNVIDVS
                     ITFLGVFYIGVFLDFIIITINGFEKGSIYVWLIFVISFMTDIFAYFSGYLLGKHKLIP
                     KVSPKKTIEGAIGGIIGSTLCCILFGYLFGTDLLQLAIIGSIGSVIAQLGDLFASSIK
                     RYVGIKDYGKIIPGHGGILDRFDSVILVAPFVYSAIKFFIR"
BASE COUNT         7597 a         1850 c         3218 g         5823 t
ORIGIN      
        1 tgtatttaat tagtatgata tagataaaag tatttatttt aattgtctat tatctgaaaa
       61 agtctttact tagaaatcat aaaaatcaaa ttaattagga aaagaaaggg tgtgtataat
      121 gtgattgaga ctggatttgt atattgtagt ttcttggttg tattcgtagg tgtaattttt
      181 tttatggttg ataaattgaa atggaaggta tttgatgtta ttaatccaat gcttttaata
      241 tacttaggtt cagctatact tggatcattt ggtttatttg cacagaatga agatgttgga
      301 acgtatcaaa acataataac agtgaacttc cttccattaa tgttagtgtt tttgttaatt
      361 caatgtgatt taagaaaaat attaaagatg gggcctaaaa tgttattatc atttttctgt
      421 gctacattta catttatgct tggatttgtt atagcattca taatttttaa aaattcaatg
      481 ggtgcagatt catggaaaat tcttggggca gcatctggtt catggatagg tggctcatca
      541 aatatgattg cagcagctaa tgctctagga gttgcagaag aaggacttag ttatgcaata
      601 cttatgggtt ctataggata tacagtatgg atgtctgttt gtctaatgtc tgtgaaattt
      661 ggacctaaat ttaacaaatg gacaaagtgc gatacaagtt ttatagatga ggttacatca
      721 aaacttgaaa aagaaaataa agataatacg gcacctacgt ttgtagaact tatgatttta
      781 ctttctgttg ggtttggagt tgcgtctttt gcacaaattg tatccaagat acttccaact
      841 tcaggtatac ttaatgaaac tatgtgggta gtacttgttg catctacagt atcaatatta
      901 ttgggtatga caaaaatatc aaagcttaaa gggagtacac tggtaggaaa tgtgtttatg
      961 tatttactcc ttgcagctac aggtagtaaa gcaaatttct ttggattgtc agaagcacct
     1021 gtttacataa tgtttggatt ggtagtagtc cttgtacatg ctatttcatt tatagggctt
     1081 gctaaactat ttaaacttga tttatttact tgtgaagtag gaagtatagc taatatagga
     1141 ggagtaacta cagctccaat gattgctggg gttcacaatc ctgtattaat accagtaggt
     1201 gtacttatgg ggcttctagg aaatattata gggacttatt gtgctcttat ggtaactcaa
     1261 atattacata tgttagctta ataaaaatat ggtataaaat taataattta aataagaaaa
     1321 gtcatttcaa tttaagcaga agcttttact gaaatggctt ttttgtttga caagataatc
     1381 tatttcaaga agatgttttg acatatttag tgtataatat tgtaaaattt actaaaaacg
     1441 agatatattt aatttttata ttgaatcgaa cgtctgtatg atgtataata aatatacaga
     1501 acgaatgttt gcagaacggg tgttttttga atttatttta ataatttatg aatatatatc
     1561 agaatgcata aatatattta aatataaaga ttaaaaagaa tttaaaggag tgttgataac
     1621 ttatgataat tccatcaaga agaatacaag atataacatt aacaaattta aaaaatggtg
     1681 aagtaacttt aattgaattg gatgaaatat acaagaagat gggattttta tttgttgtta
     1741 gtgaaggcaa attgaaaaag ataaaaaagg agaatcatca ttagaaatga atgaaataat
     1801 aaatattata atagtttata aaacctaact tatgtagaat ataaatactt aagttaggtt
     1861 tttttgtgat aaagtttata agtactcaat tttataagat aaataatggt cttaagtgaa
     1921 aagtaaataa gtttaaattt tagtaagtat tatattgcat aagaggtgat attattatga
     1981 aaatagtaac ctacaatatt cataaatgta tggattcaaa taatagatta actctaacta
     2041 aaatggggtt atatttaaaa caattggatt gtgatgtaat ttgtttgcaa gaagtattat
     2101 atcctcaatt tttagcttta aaagctgttt taaatatgga tggtgtcttt gcgacaaatg
     2161 taaaaaaagt aaatatgata tatggtattt gtacatttac aacatctaaa atgttaaaca
     2221 gtaatcattt tttcttaact agcaaaaaag aacaacgggg agctctttgt ataactatag
     2281 atgcatatgg aagaattata aatgtaataa atactcactt gggacttgat aggcaggaga
     2341 gagcaaaaca attagacgaa ataatagact ataggaacag attagtgggg atagttattt
     2401 tatgtggtga ttttaatgag aaaaatgtct ttttaagtat gtttaatgat atggctattt
     2461 cactaaacaa gtcttactta ccaacatttg aaaaatcaaa ctctagaata gattacattt
     2521 ttgttaataa aaatactgaa ctaaaaggat acacagtaga aaaaatttac ctgtcagacc
     2581 attatcctgt aataggttac atttaaattt caatataaat gaaattagtt gttataaaat
     2641 aaacaatttt ttgttaagaa atagtaaaag aaatataata aaaaatatca aaaataaaac
     2701 taattataag acataaattt acaataaagt tacatttgat taaattcctt gtttaacaaa
     2761 agctattcaa atataatcta aggtagtttt gaaatgggaa ctctattatg caaatttaag
     2821 ctagtgttaa aatgaggtga agttatgggc agaagaacaa caagagtttc aagattaggt
     2881 aaagaaaaaa aacgaagtgt tttaattgta ttggcagctt tagttctaat aatgggtgga
     2941 tttacttatt tttttaacag taaatttctg tacaatggga aaatcgctaa aaatgtatat
     3001 atagaaggag taaatgtatc tgatatgact aaagcagagg cattaaaagc tataacagat
     3061 aagtatactc cagaagattt aaatcttgct tatgatggga aaaaatatac aatatcacca
     3121 aaagatattg atttaaaata tgatacagaa gatgttgtaa aagatgctta tgaaagtaca
     3181 aaaaaagggt cctattttca aaacttaaaa aaatatattg atataagagt gaataaggca
     3241 aatatgaaga taaaagctga atatgatgag gcaaaactta gttccaaagt gtcttctata
     3301 gcagatagta taaatgttaa gatgaaaaat gcttctatta gtgttggaag tggtggacta
     3361 agttatacag actctgttgt aggtagagaa tttgatttgg cagcaaataa agagtctata
     3421 tataatatga taaaaaataa agagcataaa actttagaac ttaaagtaaa tcttcaaaaa
     3481 ccagatataa caactgaaca agtaaaaact gtaaattctg ttataggtca atattcaact
     3541 acttattcac aagctgtaga gggtaggtca tataatgtag gattatcagc aagaaaaact
     3601 agtgatgtat tattaatgcc aggtgaagaa ttttcataca ataaacttac aggacctagt
     3661 aataaagcaa atggttacaa agatgcacct gttatagttt atggtaagct agaacaatca
     3721 gcaggaggag gtgtttgtca aacatcttca acagtttata atgcggctct tctttcgggt
     3781 atggagataa ctcaagttac aaatcattca tctgcatcta cttatgtgcc taaagggaga
     3841 gatgctactg tgagcgatgg aggattaaac ttaaagttta aaaatccata taagcatcct
     3901 gtatatatta aaaattatgc aggtggagga agtgtatcat cagtaatcta tggtaattct
     3961 ggtgacaaac caaatatatc tatagaggta aaacaaactg gtcagaataa atattctaca
     4021 tatcgaatat ttaaagattc aagtggaaag gtcataaaaa aagaacatat atcaaatagt
     4081 tcttataaag aattaaaaaa atagataatt ttttagagaa atatttgtaa tataaaaggg
     4141 agtgtctcaa aatgaacttt ttagtttatg aggcactctt tttctgtgaa atcaaatata
     4201 ttttcatcat ttcaacaata caaaagaagc gtatctctat tttgagacag ccttttttgt
     4261 aaaaattaac actattagtt cttgttttaa tattacaatc attaatatat agaaaatatt
     4321 cctatatatt ggtataattg taaatagatt tagttatata aaatgtatga ggaggtgaca
     4381 tggttgaatt ttataggcaa tagatatgag gtagtaaatt ctgacgacgt tttagaaatt
     4441 aacaaaatct ataaagctag agatgttttt tacaggaaaa atgtgttaat aaaagttata
     4501 aagcacaata attatatctg tgaagatttt gtttcaaatt taattgatga aagtactgct
     4561 ttagatgaga taaactctcc ttatatacta aaaataatag atgttgggat tcactgtaca
     4621 gaagaaacaa cattatatta tgttgtaagt gaagacttta atggtatcgg actagatgaa
     4681 ttaattctag gtaattatct tcatttagaa gcaattgtaa acataatgat acaagtttta
     4741 aaagctttag aaatgataca taggaatcat tcatatcatg gtagtttaaa atcgagtagt
     4801 ataatagtag atacagaata caatataaaa atttgtgatt ttggaattac aaaagcaaat
     4861 aatggggtta atacaagaag ctatggaaac aggagatatt tatgcccaca tcaactatgt
     4921 ataaattata ctgataaaga aagtgatttt tttgcaacag gtcttattct atttgaatct
     4981 atatttaaaa aattgccttt tggagaatca aattcagaag aaaaaatgct acaatctatt
     5041 gataagggat tagattggaa tagtataaaa gcaattaatg gaaatactga acttataaat
     5101 gttataaaaa ggcttcttgg aagaaataat aagtatacca gagccaatga tattattatt
     5161 gatttaagta aagtaatgta tgaaaaagca tatatagaag ttgaagatga gaaagaagaa
     5221 gagcagaaac aagacaaagt tatacaagtt aaaaaagaat ataaaagtaa aatgagaaaa
     5281 aaattacata aaaaacttgt tgttgccggt ctagctatag tcatgatttc aatgattatt
     5341 attagttcca taatataaaa attgtatatt aagtatttta aaatcaatgt ctataaagga
     5401 tatacataga aattttagtg tagtcttaaa ttatgaaagg aagtggttat tatgttaaca
     5461 aaaaataatg aggtattaaa cgtctaggag tattttaaca aatagccacc tgcttttaca
     5521 gtttagaata aaaaagctgt ggctaaaggt cacagctttt tgctactttt taaaggcagg
     5581 agaatattaa aaaggagcaa attatgagca atataaaaat aatagcaagt aataaatgtt
     5641 ggattgaaga tatagcaagg aaacaacttg aagatatttc aaagttaaat ggaattttaa
     5701 gagtagtagg attacctgac ttacatgcag gtaaaatacc tgtaggttta gcagttgaga
     5761 ctaaaaatat tatttatcca catataattg gaaatgatat aggatgcgga atgactttat
     5821 ttaaaactgg agttctaaaa aagaaattta aaaaagacaa atggattaag tcacttagta
     5881 agattaaaga tttgtctgat atagaaataa aaaacacata taaagaagaa tgtccaattt
     5941 taaatttagg aactataggg agtggaaatc attttgtaga aattcaatgt ataagtgaaa
     6001 tttataataa agaacaattt gaacaattaa aattttcatc tgatgatatt atgatgttag
     6061 ttcactgtgg gtcaagaaat tatggagaag atattttaaa aaaattttat gataaagatg
     6121 gacttgaagt tgaaagtgag aaagctatag attatattaa aaaacatgat aatgctttaa
     6181 tgtgggcaga gcgtaatcgt gaagctatca gtaaaaaaat tatgcagtca ataggtacat
     6241 ctggagatgt tgaaacaata ttctctataa atcataactt tgtagagaaa agggaagata
     6301 aatttataca tagaaaaggt gctgtttcaa gtgaaagagg agctgtgatt ataccaggtt
     6361 caagaggcag tctatcatat atagttatgc ctactgaaaa tacagagata tctttatatt
     6421 ctctatcaca tggagcaggt aggaaatggt ctcgttcagt ttgtaaatct cgccttaaaa
     6481 gtaagtatag taaagatact ataaaacaaa ctaaatttaa aagtcagatt atatgtaatg
     6541 atgtaaattt attatttcaa gaagctccag aggcatataa gaatatagag cagattattg
     6601 aaagtttgat agaatatgaa cttattcaag tagtggcaac tatgaagcca ttgattactt
     6661 ataaaggata atttttaaag ttaaaaaaga ttaaaattat attataaata gctaatttta
     6721 tggaacattt aaaagtgttt tattattagc tattttttta ttttgtagag acgataattt
     6781 atagagctaa attctttgat atataatgat tacaaagtta gactgtattg gaaactgcac
     6841 atacatgaat tgatgacaat ataagtgatt ccaaaatata aatgaaagta taagcttatt
     6901 ttcactataa aaattttcac tgtacaaaaa cattaatgac attattttta ttgacataaa
     6961 tatataattt atggaataat attagaagca ctgatataag tgtttaaata aggatagaaa
     7021 aggagaagtg ttttatgaaa aaaaatacta acattaatga gtccggagtt aaacttctta
     7081 ataaataagg agtttgatat ataataactc cttatttatt aagttgttcg caaaataact
     7141 attatcaaag taaatgatag ggtgatttaa aagacgataa cttataaata aaggagaaaa
     7201 aataatgaat agtaatacat ttgaaagatt acaactaaat gaagttaaag aattaataaa
     7261 aatacattgt gtaagttcac taggaaaaaa tttaatagat aaattaactc ctagtgggaa
     7321 tattggagta gtaagaagga aattagcaga aaataaagaa gctagaaaga taattgaaaa
     7381 tagtaatcac ataccacttg aaggattgtt taatgcaggt tctacaatag ataaaattga
     7441 aaaaggaatg ataatagaac ctgttgaact tgtaaatatt gaagattttt taagaggttg
     7501 taggaagatg aaagctttta tgttagaaaa agaattttat tcacctacat taagttctta
     7561 tgccttaaat ataacagaat gtaaaagtat agaagatgag ataaattact gtataaaatc
     7621 taataaagtt gattctaatg ctagtaaaga attaaaaaag ataagacgaa atatagaaat
     7681 tacagaagga aagataaaag atagattaaa taaatttata acatcaactg taaataaaaa
     7741 gtatatacaa gagtttataa taagtaaaag aaatgataga tatgtaatac caattaaatc
     7801 ttcttataaa aatgaagtta atggtactat attagataca tcatcaaaag gaaatactgt
     7861 atttattgaa cctattagtg tttcaaattt aagtacagag ttaactatgc taaaagctga
     7921 tgaaactatt gaagaataca aaatattatc ttatttaaca gaacttatat ttgagaagat
     7981 aagtcagata aaattaaata tagagatact ttcagaatac gatatggtat ttgcaaaagc
     8041 taagtatagt caaaaaataa aaggaattac tccaaaaata aataataatg gctatataaa
     8101 aataattaaa ggtaaacatc cacttctaac aggagatgca gtacctttag attttgaaat
     8161 aggcaaaaat tatagaagtc ttataataac aggtcctaat gcaggaggaa aaactgtaac
     8221 ccttaagact gttggtttac taactttaat ggttcaatgt ggatttgata tttctgcaaa
     8281 agaaggtagt gaatttagtg tatttgaaaa agtttttgta gatatagggg ataatcaaag
     8341 tattgaaaat gccttaagta ctttttcatc acatataaaa aatattgcag agattatgag
     8401 tttatcaaat aattctactc ttgttctgtt tgatgaaata ggaagtggaa ctgaacctaa
     8461 tgaaggagct ggtttagcaa tatcattatt agaagagttt tacaaaatgg gatgtataac
     8521 tatagcatca actcattatg gagagataaa aaagtttgct acattgcatc cagaatttga
     8581 aaatgctggt atgatgtttg ataaagaaac gttagaacca ttgtataagt taactattgg
     8641 aaaatctgaa gatagtaatg ctctttttat ttctaaaaaa atgggaataa aaaatagagt
     8701 tttagataga gctaaagaat atgtaattga tagaaactac aatttagatt tagttaaaag
     8761 aagtaagcta caatctaata ttgaagataa aaatagttct gaagtcattt taaactatac
     8821 agattataat gtaggggata aggtaaaatt actagatgaa gatgattttg gaattgtata
     8881 taagcctatg gacaagttta ataatgtaga agtattgttt aatgataatt ttatttcagt
     8941 aaatataaaa agattacaac ttagcataaa agcatcagaa ttgtatccag aagggtatga
     9001 tttagatgta ttatttacta gttttaaaga aagaaaatta gaaaaagata ttcaaagagg
     9061 ttcaaaaaaa gctcttaaaa agattcagaa agaaattaga gagaatagaa aataaatata
     9121 aaaagcacaa aagaaagcaa tctaaagaga aaagtttatc tttagattgc tttcttatta
     9181 acatatcttc ataaatccaa tgactaacaa gattaaacca cttaaccaag ataagtttaa
     9241 atttacgttt ttaacaaaca tatttcctag taaacaacca agtaatactg caattatatt
     9301 tgatattaaa gaaaatagaa taacttgtat ataattcaca cctacaaggc cactaccaaa
     9361 accgatagct aatccatcta aacttaaagc aagtgcaagt gtaaatgctt cagcagattt
     9421 aagcacttta gatttacttg tatctaagac atcaggttcg atacttacat taaaatttaa
     9481 tttaaggtct aacatattaa aattataatt ctttgagtgt atagattttt tcttaaaata
     9541 agatttaaaa aaactttcaa ttagtctagc acttcctaat aaaaataaaa taaagaaaca
     9601 tattaacatt gttatatttt gaggtaaaaa atctctaact attgtacctg caaaaagcga
     9661 tattgctaaa atagctgaac aaactacgct gataattata tttgaatata agggaacttt
     9721 aactttattt acaccatatc caaagcttgt cacaaaggca tctatacaaa gagaagtaac
     9781 taataaaatt gattcaatca cagtagatta acatcctttc tcttaaattt tgtacttata
     9841 ttagttatag tattgtaaaa atggataaat tgttacagat aatccaataa attgttgata
     9901 aaattccaac atcatacaac acctaaataa caaaagaatc atatcatata ataatataaa
     9961 accaatcata ataaagcggg tgaaaataat ggaacaaaat aataaggttg ggaatttcgg
    10021 tgatttgttg aagattttat tagatgaaaa agaattatca atgggagaac taagtaaaaa
    10081 aagtggaatt gataaatcta ctatatctcg tatagctaat aataaacaaa agccaaatat
    10141 aaatcattta gaaaagatgg caatacattt aaatattaac ctagaagaac tgttgaaagc
    10201 ttcaggatat gaatttagaa acagcaataa tcaaatattt aatgcagata gtgattttag
    10261 taactttgat gatattcttg gatttgcaaa tttaatcaat gataagaact ttaatggaaa
    10321 tattgaaaaa gagttaagta agtgtaagtt atatgtccaa acagatgaag gtaaaaaatt
    10381 actttttgat aattttaata aaaaaataga ttctattgaa aaacaaggtc aatttacaga
    10441 tagattaaga caaatgtatg ctgatttttg tacagatgga cttacaataa agaaatattt
    10501 attgattgga agtatgctac tttactttgt tatatcaaca gatgtgattc cagacttcgt
    10561 gttcccaata ggatttatgg atgatttagt agcattaaat atagttacaa aattacttaa
    10621 aaatgataag taagttttag aatcatattt aatatataaa taaatcaaag tatataaaat
    10681 ttattatttt ttatatgaaa caaattaaaa gcacaatgaa gtagattaaa aatttaaaac
    10741 taagaatcta atatatattt tgtaactatt taagtatata aaataaaata atatccaaac
    10801 taatacaaaa tagtaataat tgttttgtac tggaggatat atatttatga attgtaaatg
    10861 gatatctaaa atagatgaga gaaaaaaatg tcatagagaa gcagattctt ctggatattg
    10921 tatctttcat aaagaaaata agtctgatga agagatacag ttgatgatgg atactcttca
    10981 taaagaagag ataagtgaat ttaatggatt tgtttttgaa aatgaattta atgcggaaga
    11041 aatattaact tacaattata aaatactgga tttttctgaa tccatattta aacaaaaagc
    11101 aaattttaaa aaatatattt ttaaaaagaa tattattttt aactatacag aatttagaga
    11161 taaagtttta tttaatggtt gtgtattctt agaaaactgt gattttaata gaaccatatt
    11221 tagtaaacac tatataaatg accgtatatt tgaaaaagtg aaatttaaag gacctgattt
    11281 ggtagttaat aaagtagaaa attttccacg aatggatgga ataattttta gcatgtgtac
    11341 aaaatttgtg ttaaagaatg ttgaatatgg aaaaagtgag tatgagcatg gcaagataaa
    11401 ttatagaata gctagaaatc aagcaacaaa aattggagaa tatgagatga taggatttta
    11461 ctattataag gaaagaattt atagtagtaa aataatgaaa cgttctaatt atcctacttt
    11521 cagtgattat ttagttgaaa aattttttga ccaaatagca cgttacacaa caggttatgg
    11581 agaaaagcca tggaatatat tattagttat tatagcaata ataagtgttt ttgctttatt
    11641 atacttattt gtaggcatag aaagttcaaa tagcacactt gtagctttag atataaataa
    11701 tataggtgat tactcactaa gtgagatttt caaaatgtat atggatttat ggtattttag
    11761 catggctaca tttagtacag taggatatgg agatatggtt gctacaagtt tgattgggaa
    11821 agcattggca ggtatagaag tattttttgg agttacaata ggagcaattt gggcatctgt
    11881 gattattaaa agaatgataa ggtaatattt gtgtaaatat ggataggtat taattactag
    11941 atataaattg gactaaatag ggaaaattta aatataaata tacttaataa tccaagaagg
    12001 tgaaaaattt gaaaaatgca ctaaaaaaaa ttatatcatt agccatgatt ctagttttta
    12061 taataccaaa ttattcatat gcagatgata aatctgtaga caagtattca aaaacatcta
    12121 tacttataga ccaagaaaca ggtagagttt tatatagtaa agaacctgat atgaaggtac
    12181 cattagctag tttaagtaag atgatgactt ttttacttgc aatagaagct attgaaaata
    12241 aagaagtaaa agaaactgat aaagtaaaaa tagacaaatc tattgcatca gtaaaagggt
    12301 caagttataa acttaaagat ggtgaagaag tgccacttat agagcttatg agaggtctta
    12361 tgattgtatc aggaaatgat gcggcaattg ctatagcaaa acatatttgt aaaacgaaag
    12421 aagcatttgt agatagaatg aataaaaaag caaaagaaat aggaatgagt aatacacatt
    12481 ttctaaatcc aaatggtctt ccaatatacg atttaagcaa ccccaaaaaa ccagcaaaag
    12541 aaaatatctc tactgcaaaa gatatagcta ttcttggaaa atacatgttt gaccattatg
    12601 aaaaacaagt aacagctata actgatatgg agacatatac aaattcagat agaagttttg
    12661 aaaaaagcaa tacaaatgca ttattaagaa ttataccaga agtagatggt ataaaaactg
    12721 gatatactgg caatgctgga tattgcttat cattttctat ggttgtaaat aaaaatgata
    12781 aaaatgagaa aaaacgtaga gtaatagggg ttgtattagg tactaaccat aaaaataaaa
    12841 gaacctctgc ttcattagct ctactgaaat atggaaaaga aaatttcaat atgaaaaaag
    12901 taattgataa agatagcttt attggtaaga aatatataaa aggaatgaaa gagttagagg
    12961 ttacattaaa agcaaaagat gaactttata caatattaaa aggtgatgaa agtataaaat
    13021 cagaagttaa gattaaaaat atagagtacc ctgttaaaaa aggtgatact atgggtatta
    13081 taaaatatta tactaattca ggtgacttac ttggaagtgt agatatagta agtaataata
    13141 gtatagataa cgtatcatta aaaacaaaat taaaaatgaa atttgcaaat taaattcaaa
    13201 aaatggtata aaatacacaa aaaaatataa aaatagaaaa tatggaaaaa atattgttat
    13261 ttcttcacct ctgtgatata ctactagagg tgaaaaaata aaataaatca cacacagcat
    13321 tgggatcctt aaaaggtgcc tattacatgg ttttttaggg agaagatcaa gctggaggta
    13381 taaaaccagg aggtaagata tgtcagtaat atcaatgaaa caattattag aagcaggtgt
    13441 tcactttggt caccaaacaa gaagatggaa ccctaaaatg gctaagtata tattcacaga
    13501 gagaaatgga atatatataa tcgacttaca aaaaacagtt aaaaaagttg aagaagctta
    13561 caagttcact aaagaagtag ctgaaacagg aaagccaatc ttattcgtag gaactaaaaa
    13621 acaagctcaa gatgcgataa aagatgaagc tgaaagatgt ggaatgtact ttgttaatga
    13681 aagatggtta ggtggaatgt taacaaacca caaaactata aaaacaagaa taaataaatt
    13741 aagagaatta gaaaaaatgg aagaagaagg cgtatttaat gttcttccta aaaaagaagt
    13801 tataaaatta agagctgaaa aagaaaaact agaaaaatac ttaggtggaa taaaagacat
    13861 gcctgaatta ccaggtgcaa tgttcgtagt tgacccaaga aaagaaaaca tagctattca
    13921 agaagctcat agattaggta taccagtagt tggtatagtt gatactaact gtgacccaga
    13981 acaattagac tttgctatac caggaaatga tgacgctata agagccgtaa aattaataac
    14041 tggtgctatg gcaacagctg taattgaagg tagacaaggt gctgaggaag aagtagctga
    14101 agaccaagaa taataatttg acaattaaat ggtaagggtc gcccttacca tttataatat
    14161 ggaatagaat aagtaggagg aaacttaaaa aatggctaat ataactgctc aaatggtaaa
    14221 agagttaaga gaaagtacag gcgcaggaat gatggactgc aagaaagctt tacaagaagc
    14281 tgaaggaaac atggaaaaag cagtagattt attaagagaa aaaggattat caaaagctgc
    14341 taaaaaagct ggtagagttg ctgctgaagg tctagttgca atagaaatga atgatgataa
    14401 tacagttgct tctatggtag aagttaactc agagacagat ttcgttgcta aaaacgaaga
    14461 cttcaaagtg ttcgttaaag atgctgcttg tatggcatta gctactgata aagaagatat
    14521 agcttcttta ttaggtgaaa ctcataaaga gggaataact ttacaagaag ttttaaataa
    14581 tagagttgca aaaataggtg agaaattaga ctttagaaga tttgctaaag ttgtaactaa
    14641 tggacaagtt gctggataca ttcacggtgg tggaaaaata ggtgttcttg ttgaaatgga
    14701 aacagaagct agagatgcta aagttttaga attaggtaaa gatgtagcta tgcaagttgc
    14761 tgctatgaat cctaagtatg tttcaagaga tgaagtagat gctgaataca tagcacatga
    14821 aacagaagta ttaactcaac aagctttaaa tgaaggaaaa ccagctaata tagttgaaaa
    14881 aatggttaaa ggaagattag aaaaagaatt aaaagaggtt tgtttattag agcaaacttt
    14941 cgttaaaaat ccagatataa ctgttaaaca attagttgct gatgttgcta aggcagtagg
    15001 ttctgatata aaagttgtta aagttgtgag attcgaagtt ggtgaaggta tacaaaagag
    15061 agaagaaaac tttgcagaag aagttgctaa gcaacttaag taataaccaa agagagaaca
    15121 cgcaggtgtt ctctttttta aaaaatagaa aaaattggat atgaaggatt gaaataggag
    15181 gtttctgatg gataaaccaa tgtacaaaag ggtattgtta aaattaagtg gagaagcatt
    15241 agcaggagaa agaggttttg gtataaataa tgatgtagtt aatgatattg ctattgctat
    15301 aaaaaaaata caagaaatag gtgttgaagt agctgtagta gtaggtggag gaaacttctg
    15361 gagaggcaga accagtgaag gaatggacag aactactgct gactatatag gaatgttagc
    15421 tacagttatg aatgcaatgg cgctacagga tgcactagaa aatatagatg ttgctacaag
    15481 agttcaaact gctatagaca tgagacaaat tgcagaacca tatataagaa gaagagcagt
    15541 tagacactta gaaaaggaaa gagttgttat atttggtgca ggaacaggaa acccttactt
    15601 tacaacagat acaactgctg ctttacgtgc tgctgagatg gaagcagaag ttatattgtt
    15661 agctaaaaat gttgatgcag tatatgacaa ggatccaaaa gtacatgcag atgctaagaa
    15721 atttacagaa ttaagttaca tggaagttat acagaaagaa ttaaaagtaa tggattctac
    15781 agctacatct ttatgtatgg ataataaaat tccaataaag gtatttgagc ttacaacaga
    15841 gaatataata agagcagtaa aaggcgaaaa tataggaact actgtaaaat aatgaagaat
    15901 gaaggaggag taaaattatg aaactggaaa tacataagca attagaagag aaaatgaatg
    15961 ggacaattga tgctttaaag tttgaatttg gaactataag agcaggaaga gctaatgcac
    16021 aaatgctaga caaaataaga gttgattatt atggaactcc aactccaata aatcaaatag
    16081 gtgctatatc tgtaccagaa ccaagaatat taatgatatc tccttgggat aaatctgcta
    16141 tgcatgaaat agaaaaagca atagctaact cagacttagg attaaatcca tcaaatgatg
    16201 gtgaggttat aagactttct gtacctgctt taacagaaga aagaagaaaa gaattagcta
    16261 aaaaagctag taaagctgca gaagaattta aagttagaat aagaaatgaa agaagagacg
    16321 ccaatgagaa gattaaaaag atggaaaaag gcggagaatt aactgaagat gaattaaaaa
    16381 aagcacaaga tgaagttcaa aaaatgactg ataaatttat aaaagaaata gatacattat
    16441 tatctaaaaa agaaaaggat ataatggagg tataatattg aaaaaatatt ataacctttt
    16501 aggtcttcat gtagatgagg taaaacaata ttttgatgag caaaatataa attataccgt
    16561 aaaatctatt gaaggtaaaa aggataaaga aaaacttgta gttcctagag ttataaaaat
    16621 atctgagata ggtgatagtg tagaactgat aatcacatac ttttctgact ccttagttta
    16681 aggagtcaga acaatattgg aggcaaaata tgaataacaa cattatatat gatatagact
    16741 taaataacat acctactcat attgctatta taatggatgg aaatggaaga tgggcaaaag
    16801 ctagatttct tccaagaact gcaggacata aggctggagt agaaactata agagatatag
    16861 taaaagaatg ctcaaaatta ggtgttaagc acttaacatt atatgcattt tcaacagaaa
    16921 actggaaaag accgaaactt gaagttgaca cacttatgaa cttattatct acatacttaa
    16981 gaaatgaaat agctgaactt caccaaaaca atgtaaaagt aactgctata ggagatataa
    17041 gtgctttacc aaaaacttgt ataagagaat taaactcagc taaggaactg acaaaaaaca
    17101 atacaggagt taacttaaat ttagcattaa actacggaag tagagcagat ataaaaaatg
    17161 ctcttataga tatagtaaaa aattgtgaaa gtggtaaaat agatataaac aatattgatg
    17221 aagatattat aaaaaactat ttaagcacaa agtctatacc agatccagac ttggtaataa
    17281 gaacaagtgg tgaacaaaga ttgagtaact ttttactttg ggaagttgct tattctgagt
    17341 tttactttac tgatatacat tggcctgatt ttaaaaaaga agaactacag aaggctatat
    17401 acgtatatca aagaagggat agaagatttg gaggacttaa gtaaggagat tattttatgc
    17461 ttacaagaat tattgcttca ctagctctgg ttccattatt tctatttgtt gtatatggag
    17521 gtattcctct atatatagct gagacagcaa tagtttatat tgcattgcat gagttttata
    17581 aggcatttaa aataaaagat gtacatccaa tattcattat aggatattta ttttctattt
    17641 atttagctgt aaaaaatatt tttaatttac cattagaata tacttatgca gtaattttta
    17701 ttttattttt agcaagtata atttatatgt tgatgggcaa aaacaatgtt atagatgttt
    17761 cgattacgtt tttaggagtt ttttatatag gagtattttt agattttata attataacta
    17821 taaatggatt tgaaaaaggt agtatatatg tatggcttat atttgtgata tcttttatga
    17881 cagatatatt tgcatatttt agtggttatt tacttggaaa acataagcta attcctaaag
    17941 ttagtcctaa aaagactata gaaggagcta ttggaggaat aataggaagt acactttgtt
    18001 gtattttatt tggatattta tttggcactg atttgcttca attagcgata ataggaagta
    18061 taggaagtgt aatagctcaa ttaggagatt tatttgcatc ttctataaag agatatgtag
    18121 ggataaagga ttatggaaag ataatacctg gtcatggggg tatattagat agatttgata
    18181 gtgttatatt agttgcacct tttgtatata gtgcgattaa attttttatt agataaagat
    18241 tggttggatt taaaagagca atctataatt gctagtaatg aaaatagcta tgtaactttt
    18301 aaatgcagag atattctgca gttattagtt acatggctat tttcattgtt caaaaattta
    18361 gaagaccttg gggaattgta taagaatagg tattacttta taatagtata ctatatttgt
    18421 agtgagtata ttttttatac tataactatc attaaaaaat atttttttgt ttaataattt
    18481 cgatattt
//
LOCUS       DAMJXI010000072        18041 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.076, whole genome shotgun sequence.
ACCESSION   DAMJXI010000072 DAMJXI010000000
VERSION     DAMJXI010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18041
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.076"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            527..1387
                     /locus_tag="PC465_003072"
     CDS             527..1387
                     /locus_tag="PC465_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2650356.1"
                     /translation="MKIIQILNNNVALVKRGKNEIIVFVKGIGFKKRVGQVINENEIE
                     RTYILDSYDMLEHFSYLLQNSDSNNIVLINEIIEYGEKALNIKSSDYLSLTLLDHLEF
                     LLKRCEKNQFIKSPLVWNVKRFYPKHFEIGMHALKLIGDSKGINLPDDEAVSIALHFV
                     NMEVNKESHDSTIVELRTLADIVSIIKYHFNVELDETSTNYMRFTTHLQYFIQRIMSD
                     EASIDEDNSIDLYKQVSQLYPKSFGSVQKIRKYIKSQFNVDISISEETYLMLHINRVT
                     QRLEAKSDEI"
     gene            1377..3248
                     /locus_tag="PC465_003073"
     CDS             1377..3248
                     /locus_tag="PC465_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2650357.1"
                     /translation="MKYKDLNENIIKLIGGKENIKSVAHCVTRLRFTLNDRSIAQTEE
                     IKKLKGVIDVVSNDVAYQIIIGTHVVDVYNEFMSMIGLSSSESSIKSERKKGIRGIKG
                     IFNSIFVVVSETMTSVIEVLLAAGILASILALLNMSGILQSDSPTYQILDTLRSATFH
                     FLPVLIAIASAKRLNVNPYIAVVLAVTLLSSSIDGVEGLSLFGINLQATTYANSFIPI
                     LLGVWAMGIIIEGLKKILPKALHYFLVPVLSLIITLSVTLTVFGPIGMWIGDGLNYAC
                     MFLIDTLGNWSVVALYAALQPLLIVFGAANFTMPISLNSVTTLGYDPIFMGAATISDI
                     AVCGAMFGYFLKTRNKEQKQLFGTVSFSALMGVTEPSVFGVFMKYRRPFVAVMIGGGI
                     GGLIAGLAQVKTYGMVWGLAALPTYLVGGEVSNFTFMIISVVVSFVAATAASYLLGIP
                     SDEKEEVKGDNEKELELIINENNSRTISIGNVAKGQVIALGEVNDKAFSSGALGKGVG
                     VIPSESKSTVISPVDGTITIVFPTKHAYGIVTDEGLEILIHIGIDTVNLDGKFFESLV
                     TQNQRVKKGDALAVFESDKIIEEGFDSTIITVVTNTSDYLDVISSNDESEELLTVIV"
     gene            3268..4722
                     /locus_tag="PC465_003074"
     CDS             3268..4722
                     /locus_tag="PC465_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HDF2650358.1"
                     /translation="MNIKDTFFWGGSIAAHQCEGSWDSDNKGPAIMDFVTKGSYETPR
                     VITDKIEEKLDYPSHNGIDFYNRYKEDIALFKEMGFSALRISIDWSRIFPNGDDENPN
                     ELGIKYYEGLIDTLIENNIEPIVTLYHFELPMNLVHKYGSWNNRKLIDLYLKYSETVI
                     RRFDDKVKYWVTFNEMNHIDPQTEHSDIFTYMIAGIKYSEIENKVQTLANVGYNMTLA
                     GVKVAKLAREINPNNKVGCVFGLNPIYPYNCNPSNVLNAFLDNDRDYYQIDAMCNGKF
                     PQYKLKEYEKNNITIEVTDEDKKAFKEGKLDFIGLNYYFSSVSTPKENLSGDKSLFGG
                     IQNPYLEQSKWGWAIDPIGLRFTLNYIYRKYQLPILITENGLGAYDKIEEDGTINDDY
                     RIEYLSKHLSQMKSAIEEDNVECFGYLMWGPIDLVSATTGQMSKRYGFIYVDLDDEGK
                     GSFKRYKKKSFDWYKEVIKSNGEVLDFSTDIVVG"
     gene            5747..6955
                     /locus_tag="PC465_003075"
     CDS             5747..6955
                     /locus_tag="PC465_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650359.1"
                     /translation="MENFWNPLTCFTVCVMIYAFSEFLSKKTKGAISTLLFVCIIFLL
                     GFWTNILPKDITGASGILAAMSNFGIALLITNLGTLINLEDLCHEWKTVVIALVGIVG
                     IGVGCLTVGSMLFGREYALIAAPPIAGSTVAGIIVTTVAEAANRPELAAFVILVLSFQ
                     KFFGIPITTYCINKELKFKRDNGDFLKDESKSNFKLPSMRIFKEDLGKKSSTLVYLAK
                     LSFVAMIGNFVGLATLIPGFTPANYYLNPNIACLLVGLIFTRIGFLEKGILDKSQSNG
                     IIMFGCMLMLPGGLAKVTPTALFGMIIPTIGILVVGSVFIILFTAIVGKLLGYSPRMS
                     AAIGVTCMLAYPATQIISNEGIDAMEGTEEEKQRATDYLLPKMIIGGFVTVTIASVAF
                     ASIIGPIIFG"
     gene            6986..8365
                     /locus_tag="PC465_003076"
     CDS             6986..8365
                     /locus_tag="PC465_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2650360.1"
                     /translation="MIGSISINEIDKKRFKLDDLSKKIWENPEKAFKEFKACENTANF
                     LRSEGFDVEVGVGGLATAIRASFGSGKPVIGFMGEFDALPGLNQKVSTKQEAFELGAY
                     GHGCGHNLLCTAHVGAVVGLKREMIENNLSGTIVFYACPGEEQLTGKGFMARGGAFEG
                     LDLAINFHPNKISEATIGTSTAVNSVKFHFKGKTAHAGSDPQNGRSALDAVELTNVGA
                     NYLREHVTSDVRIHYTITDGGVAPNIVPDKASVWYYTRALSREAVESTYERLVKVAKG
                     AAMMTETEVEVEFLGGCYNTLNNHVLANLVSECMNEIKQEPWTREELDFAAELDRQSP
                     QQYKAMISKYNLPEGTHLYYGGGNVTNFNSYGSTDIGDVMHIVPTAYFFTGCTNLGAP
                     GHSWQFTSCAGSSIGEKGMIYASKIMAMFGAKILNNPEIAKKAKEEFDKSMNGKTYKC
                     PIPDDIPTP"
     gene            8471..9661
                     /locus_tag="PC465_003077"
     CDS             8471..9661
                     /locus_tag="PC465_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2650361.1"
                     /translation="MKNFFKEAQSIEGEIIRWRRYLHENPEIGCNLPKTVTFVTSTLE
                     KMGYSPKLTSNNGIVAVLDSENGGKTLLLRADMDALPIMEETDLPFKSKNKDASHSCG
                     HDNHTAMLLGAAKILMDNKHLLKGRVKFVFEPDEETTRGAKSMIDDGILENPQVDAAM
                     AFHSMVGKFLNTGQVAYSRGPAMASADIFEITVEGKATHGASPEFGVDPINIMSHIQI
                     ALNTILSREKPQKEPVVLTIGMFNAGNVPNAIPNKASMSGTLRTFDQFVREKLKNRII
                     EISTGIAKSFGGNAKVEFKMGTPAVINDLDVGDEIVSYVKEVIGNENVIDFPSAMGSE
                     DFSEILLRVPGVFLWIGMGSISQGYNFGMHNPKAIFNEEGLVYGSALFAHCAVKWLEN
                     NFSR"
     gene            complement(9789..11117)
                     /locus_tag="PC465_003078"
     CDS             complement(9789..11117)
                     /locus_tag="PC465_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650362.1"
                     /translation="MMKIAVITTEFLKEFVDNSIKKLNINAEIKIYIYRDFSHVGDLY
                     LEIEDRFDGFAVSGPIPKKAITKKAGTIKKPLVDFGTDLQSYYDMFLKLIFKYNTLDF
                     SRAYFDLTDWADNPKDISYYLSNGTFGDLMDSIDENASKMSLSDIAKLEKKIAKKHIN
                     LWNEGKIDFSTTRFSSIVPMLQNAGVNFHFIYPDIDLLKNTFNNLIKDIHLHRMKGNQ
                     PSVIYITVKDTNYDDSTLDQVYKILNSIKKDKLTDFIIEKNSNSFKIFTKCETIKSLT
                     KNFTACYIKESIENSTNIKVCVGYGIGNDIKQAMSSAISANKESKINPLNYSFLVNEN
                     YETIGPLLCDKLLTVSNKVTPHINTIAKSSKLSTLTIQKIISVTEILQRDEVTPKELS
                     SCLNVTVRTANRFLSSLLKSGNATILYEKQNSTKGRPERVYKLFISENKY"
     gene            complement(11735..12949)
                     /locus_tag="PC465_003079"
     CDS             complement(11735..12949)
                     /locus_tag="PC465_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDF2650363.1"
                     /translation="MRNCIIAQSGGPTAVINASAVGIYEKNLETKYFDKVYFGINGIE
                     GILNKNIIDSDSLNKDNVLNLKQTPSSGLGSCRYKLADYKINSYDYDRVINILDEYEI
                     DTLFYIGGNDSMDTVMKFSQYCKNTTCKIKFIGIPKTIDNDLLGTDNCPGFGSAAKLI
                     STLIMETYLDFSIYKNNGIFIVETMGRDTGWLAASSSLARLNDTPLVDLIYLPEIDFY
                     EDKFIEDVRKIFKEKNKAYIVASEGIRDKYGNFICEQKTSAHDKFGHSQLGGVSNYLK
                     NLIVSSSITTRVKTLELGVIQRCAMHLASYTDLKQAAEVGAYGIELSKKGYTGVMAII
                     NRTCNNPYKYEVSHTDISKIANKTKYFPKEWINEECNYITDEALNYLYPLIQGKPDIK
                     YKNGLPYFSIIY"
     gene            13375..14091
                     /locus_tag="PC465_003080"
     CDS             13375..14091
                     /locus_tag="PC465_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentose-5-phosphate 3-epimerase"
                     /protein_id="HDF2650364.1"
                     /translation="MKHIKIAAGLAHVNYGHISAVVKEAMDAGVDYVHSDAADMHDLK
                     NMQLMGGHQIIEAIRPVTDKPIECHIYTRDCDRLFIEKIAAAGCNLLIIPAEHFLGAP
                     LAYIINYCREFGMKVGLTIGCYTPLCFVDEAIYDIDRLQIVVHGVDETDGKDNWGWRK
                     SAVDLVKRARKMIDEKNPKCELAIDGGLRADNMEPLIECNPDVVILSSAIFKDKDGIT
                     AGVKNCRKAIDEAATKFGLE"
     gene            14226..14852
                     /locus_tag="PC465_003081"
     CDS             14226..14852
                     /locus_tag="PC465_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2650365.1"
                     /translation="MKKEMIKDYLLITISAFLMALAVNFFFAEHTLAPGGITGLSVVL
                     STFLSMPVENISLGISMPLLVMGLLFLGKGFGIKTLYITLMGPLFLKVIPQTHITDNL
                     LVAGVIGGLLVGTAIGIAIIRGCSTGGTDLVAMLINKVIKFLKLPVILFMLDGFIIVA
                     SGIISKNFMISIYSLISLLLIIKTIGFVTTKFGKNTEEINNINNACAQ"
     gene            complement(15052..16596)
                     /locus_tag="PC465_003082"
     CDS             complement(15052..16596)
                     /locus_tag="PC465_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2650366.1"
                     /translation="MNKRLLDIAELLLNSSDYITVDTIAEELKVSNKTIRNDLVILDE
                     WLLEFNLSLDKKTGSGVIILGNEDIKLKVIRDINDKSNCIYAYSPEDRKRYILSKLFI
                     KNSKFRIRDICNELHVSRATVHKDLVVIQNFLQNFKVTLVRKTNNGVYLEGKEKDIRK
                     AIFELATVNKSYTELKEILFSKSNECKDTPSTKIFKELFNYDFEKLSQITLHTLQVEK
                     SNLSDEYYINFLIHIAICIKRISIKRYINLSEGFFRELLEHEYFEKSKILCANLSEAF
                     DVEFIDEEVCYILLHIEGLLKSIKKTTTLEPLKNEEITEYNLSEAIAVHWGSILNLNL
                     KDDLILIKSLANHLKSVLHRINYGFTITNPILNDIKRTFPYTYKAAKESNTVIKQLMN
                     YEVNDDEIGYLALYLISAIDRSKSPLNTILICHCSDGVSNLLVQKLSFEFNQINIVKS
                     IPLSSISFTNFDDVDLILTTAPVDFEHNAELININALLSKNDISRLSTIIKKLYSEKN
                     KILSYK"
     gene            complement(16622..17263)
                     /locus_tag="PC465_003083"
     CDS             complement(16622..17263)
                     /locus_tag="PC465_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HDF2650367.1"
                     /translation="MKYLIDSANLDEIQKCLKYGFKGITANPSMYLKEKVNFHEFIET
                     CANLNPEILTAEVIGNNLYELINSCDKILNINKNTIIKINFSEVGLELINILNSKGVK
                     TACTLIFNVNQASLAINAGADYLFPFIGRNDENGNDGIKNLTEICNLISINGYNTKVV
                     AASIKNVFHLTQASLCGCDYAAVTYDLFKKASFNQLTIDGANTFERDWSKVNK"
     gene            17533..17724
                     /locus_tag="PC465_003084"
                     /pseudo
     CDS             17533..17724
                     /locus_tag="PC465_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
BASE COUNT         6689 a         2130 c         2965 g         6257 t
ORIGIN      
        1 ctaaatttaa gtatttatat attagtatat cttactagca tttaaatgaa actaaatttg
       61 aagctttacc tattaatata tcttaatagt gattaaataa aactaaactt aagactttat
      121 atgttaatat atcttaagaa tttatttgtt aacatacagt tcattatatt taaaagcatt
      181 actatgataa ttcataatag taaaatagat aatggttcag acaatattat aaatattagt
      241 gacggtaaaa tagtatcaat ttagtatata aaccttgtca gataatcgca taacagagct
      301 tgtagttata gaaaaaaaaa atatctagga aaccgttgac agatttatat ggatagtata
      361 acatatagaa tatgaaatta aacaaaaaag aattttaatt atggcgacgt agtcataatt
      421 ttgagtatgt tactgattag caggcagaac tcaagtatat atgtgaaaaa tagagggata
      481 ctctatacat atatgcttga gttcttttta ttgaagggag gaatatatga aaataattca
      541 gattttaaat aataatgtag ccttagtaaa aagaggtaaa aatgaaatta ttgtatttgt
      601 taaaggaatt ggctttaaaa aaagagtggg acaagtaata aatgaaaatg aaatagagag
      661 aacatatata ctagattcat acgatatgct agaacacttt agttatctac tacaaaactc
      721 agactccaat aatatagttc ttattaatga aataattgaa tatggtgaga aagctttaaa
      781 tataaagtca agtgattatc taagcttaac cttactagac catttagagt ttttacttaa
      841 aagatgtgaa aagaatcaat ttataaaaag tcctttggta tggaatgtta aaagatttta
      901 tccaaagcat tttgaaattg gaatgcatgc actaaaatta attggtgata gtaagggaat
      961 taatcttcct gatgatgagg cagtatcaat agcacttcat tttgtaaata tggaggtaaa
     1021 taaagagtct catgatagta caattgtaga gttgagaact ttagcagata tagtttctat
     1081 aataaaatat cattttaatg tagagctaga tgaaacttca acaaattata tgagatttac
     1141 tactcatcta cagtacttta tccaaagaat tatgtcggat gaagcttcaa tagatgaaga
     1201 taattctata gatttatata aacaagtaag tcaactttat ccaaagtcat ttggaagtgt
     1261 tcaaaagata agaaaatata taaaatcaca atttaatgtc gatatatcta taagtgaaga
     1321 aacttattta atgttgcata taaatagggt gactcaaaga ctggaggcaa aatcagatga
     1381 aatataaaga tttaaatgaa aatataataa aacttatagg gggaaaagaa aatataaagt
     1441 cggtagcgca ttgtgttact cgtttaagat ttactttaaa tgataggagt atcgctcaaa
     1501 cagaagaaat taaaaaatta aaaggagtaa ttgatgtagt ttctaatgat gttgcttatc
     1561 aaattataat aggtactcat gttgtagatg tatataacga gtttatgtct atgataggtt
     1621 taagttcaag tgaatcaagt ataaaaagtg aaagaaaaaa gggaattaga ggtatcaaag
     1681 gtatatttaa ttccatcttt gtggtagtct cagagactat gacttcagta attgaagtac
     1741 tacttgcagc tggtatactt gcaagtatat tagcactttt aaatatgtct ggcatacttc
     1801 agagtgacag tcctacatat caaatattag atacattaag aagtgctaca tttcacttct
     1861 taccagtatt aattgcaata gcatcagcaa aaagacttaa tgtaaatccc tatatagcag
     1921 tagtgttagc agttacgtta ttatcttcat caatagatgg tgtagaagga ttaagtttat
     1981 ttggtataaa tttacaggct acaacttatg caaacagttt tattccaata cttttaggag
     2041 tatgggcaat gggaattata attgaaggtt tgaaaaaaat attacctaaa gcactacact
     2101 attttttagt tccagtatta tctttaataa taactctatc agttacatta actgtatttg
     2161 gacctattgg tatgtggatt ggtgatggat taaactatgc atgtatgttt ttaattgata
     2221 cattgggtaa ttggagtgtt gttgcactgt atgcagcttt acaaccactc ttaatagttt
     2281 ttggtgcagc aaactttact atgcctatat ctttaaattc tgtgacaaca ttggggtatg
     2341 acccaatttt tatgggcgct gcaacaatat ctgatattgc agtttgtggt gcaatgtttg
     2401 gatatttctt aaaaactagg aataaagaac aaaaacaact atttggtaca gtaagtttta
     2461 gtgcacttat gggagttaca gaaccttcag tgtttggtgt gtttatgaaa tatagaagac
     2521 catttgtagc agtaatgata ggtggaggta taggtggttt aatagcaggt ttagctcaag
     2581 ttaaaacata tggaatggtt tggggattag ctgcattacc aacatatctt gttggaggag
     2641 aagtatctaa ctttacattt atgataataa gtgtagtagt atcatttgta gcagcaacag
     2701 cagcttccta tttactagga ataccttcag atgaaaaaga agaagttaag ggtgataatg
     2761 aaaaagaatt agaactaata atcaacgaga acaattcaag aactattagt attggaaatg
     2821 ttgcaaaagg tcaggtaatt gcacttgggg aagttaatga caaagcattt tcatctggag
     2881 cattaggtaa aggggttgga gttataccta gtgaatcaaa atcaactgtt atatctcctg
     2941 tagatggaac tataactata gtatttccaa ctaaacatgc atatggtata gtgactgatg
     3001 aaggattaga aatattaatt catattggga tagatactgt aaacttagat ggaaaattct
     3061 ttgaaagtct tgtaacacaa aatcaaaggg ttaaaaaagg agatgcttta gcagtatttg
     3121 aatctgataa aattatagag gaaggctttg attctactat aataactgta gttacaaata
     3181 ctagcgatta tttagatgta atctcatcaa atgatgaatc agaagaatta ttaactgtaa
     3241 tagtataaat tttaggaggg aaaattcatg aatattaaag atacattttt ctggggagga
     3301 agtattgcag cccatcaatg tgaaggttca tgggatagtg ataacaaagg acctgcaatt
     3361 atggattttg taactaaggg ctcttatgaa acgccaagag taattactga taaaatagaa
     3421 gaaaaattgg attatccatc tcataatgga atagattttt ataatagata taaagaagat
     3481 atagctttat ttaaagaaat gggatttagt gcattaagaa tatctataga ttggtcaaga
     3541 atttttccaa atggagatga tgaaaatcct aatgaattag ggattaaata ctatgaaggt
     3601 ctgatagata cattaataga aaataatata gaacctattg taacactata tcattttgaa
     3661 ttacctatga atttagtaca taaatatggt tcatggaata acagaaaact tatagatttg
     3721 tatttaaagt acagtgagac tgtaataaga agatttgatg ataaggtaaa gtactgggtt
     3781 acatttaatg agatgaacca tattgaccct caaacagagc actcggatat ttttacttat
     3841 atgatagcag gtattaagta tagtgaaata gaaaataagg ttcaaacatt ggcaaatgta
     3901 gggtataata tgactttggc gggtgtaaag gttgcaaagt tggctagaga aatcaatccc
     3961 aacaataaag ttggatgtgt atttggacta aatccaattt atccatacaa ttgtaatcct
     4021 agtaatgtgt taaatgcatt tttagataat gaccgtgatt attatcaaat tgatgcaatg
     4081 tgcaatggga agtttccaca atataaatta aaagaatatg aaaaaaataa tataactatt
     4141 gaagtgactg atgaagacaa aaaagcattt aaagaaggta agttagattt tataggactt
     4201 aattattatt tttcaagtgt atctactcca aaagaaaatt tatcaggtga taaatcttta
     4261 tttggtggga ttcaaaatcc atatttggaa caaagtaagt ggggatgggc aatagaccct
     4321 ataggtttaa gatttacctt gaactatatt tacagaaagt atcaattacc tatcttaatt
     4381 acagaaaatg gtttaggggc atatgataaa atcgaagaag atggaactat aaatgatgat
     4441 tatagaattg aatatttaag taagcatcta tctcaaatga agtctgcaat tgaagaggat
     4501 aatgttgaat gttttggata tttgatgtgg ggaccaattg atttagtcag tgcaactaca
     4561 ggtcagatga gtaagagata tggatttata tatgttgact tagatgatga aggcaaagga
     4621 agttttaaga gatataagaa aaaatcattt gattggtaca aagaagtaat aaaatctaat
     4681 ggagaagttt tagatttttc tacggatata gtagtagggt aggaataaga taaatagaag
     4741 ttaggaacta atgttaatta gtgtctagta aagcatttaa aatagagtat agggtcttta
     4801 aagtaaagtg tgtattcttc ttaaaagtaa tggcaactaa aattactata aaaaggagaa
     4861 tacacatttt ttatgtttat acttaagtaa atatttagac atattcatag tataatttac
     4921 tcattatata aaaatagtat gatttactca ctatataact ttataaattt tctggaaaaa
     4981 tgtcagaata tattgacaaa gaaaagattt aaaattataa tctatattaa gaatagtttg
     5041 acaatataaa aacaagtatt tttataaata gtgaaattat ttttattgta aatttaagaa
     5101 taatttagga ctactataaa gataaaggta tagatgtcat tatatgataa atcatacttg
     5161 tatagaaaga attttaaagt atggcttatc attgatttaa tataataaat aatttttgtt
     5221 tctagtaata gttcctagga ataagatatc taaattcgtt tagaaatagt ctaatttaca
     5281 aaggagggga tgcactaata gataaaattt ctatataaag aagacttaaa gtgaagtata
     5341 ttctgataat attggtttaa tgggtatatt attatttcgt tttagatatt ttaagaataa
     5401 tttaagacgt ttataaaaat gtattctata tctaatattt aaataaatat aagtcttcca
     5461 acatgtatac taatatagag agtagttgaa gtacaattct aactcgtaaa attatgtaga
     5521 aagtaaaaat caaaaagaaa tctagtaagt tgataactat agttaatatt tagagagtta
     5581 actctagtta tatttattta gatattttag gaataattta ggacgtatat aatatcatca
     5641 aaaaatatca agctatacca tatgtagtta agaataactg cataatatac attttataat
     5701 tattgtttta ttgataaaaa attattatat ttaggaggaa acaacaatgg aaaatttttg
     5761 gaatccactt acttgcttta ctgtatgtgt aatgatttat gcttttagtg agtttttatc
     5821 taagaaaaca aaaggtgcaa tttcaacatt gttatttgta tgtattatat ttttactagg
     5881 attttggaca aatattttac caaaagacat tacaggagca tcagggatat tagctgcaat
     5941 gagcaacttt ggtatagctt tattaataac taacttagga acacttataa atcttgaaga
     6001 cttatgtcat gaatggaaaa cggttgtaat tgcattagta ggtattgtag gaataggggt
     6061 tggctgttta acagtgggta gtatgttatt tggtagagag tatgctttaa tagcagcacc
     6121 tccaatagcg ggttctactg ttgctggtat tatcgtaaca actgttgcag aagctgcaaa
     6181 tagacctgaa cttgctgcat ttgtaattct agtattatca tttcaaaagt tctttggcat
     6241 tccgataact acatattgta taaataaaga attaaaattt aaaagagata acggggattt
     6301 tttgaaagat gagtcaaaaa gtaattttaa acttccaagt atgagaattt ttaaagaaga
     6361 tttaggtaaa aaatcatcta ctttagtata tcttgcaaag ctttcatttg ttgctatgat
     6421 tggtaatttt gtaggattgg ctactttaat accaggattt acccctgcaa actattattt
     6481 aaatcccaac atagcatgtt tgttagtagg gttgattttt acacgaatag gttttttaga
     6541 aaaaggaatt ttagataaat ctcaatctaa tggaattata atgtttggtt gtatgttgat
     6601 gttacctgga ggacttgcta aggtaactcc aacagcattg tttgggatga ttattccaac
     6661 tataggaata cttgttgtag gctctgtatt tataatacta tttactgcaa ttgtaggaaa
     6721 actattggga tattctccaa gaatgtcagc tgcaattggt gtaacttgta tgctagctta
     6781 tcctgcaaca cagataattt ccaatgaagg tattgatgct atggaaggaa ctgaagaaga
     6841 aaaacaaagg gcaacagatt atttattacc aaagatgatt ataggaggat ttgttactgt
     6901 aaccattgca tcagtggcat ttgctagtat aataggtcca attatatttg gttgatagta
     6961 aatagattta taggaggaat agaaaatgat aggaagtata tctataaatg agatagataa
     7021 aaaaagattc aaacttgatg atttaagtaa gaaaatatgg gaaaatccag aaaaagcatt
     7081 taaagaattt aaagcatgtg aaaatacagc aaactttcta agaagtgaag gatttgatgt
     7141 ggaagtaggt gtaggaggtt tagccacggc tattagagct agttttggtt caggtaaacc
     7201 agttataggt tttatgggag aatttgatgc attacctggt ttaaatcaaa aagtttcaac
     7261 aaaacaagaa gcatttgaat tgggtgcata tggtcatgga tgtgggcata atttattatg
     7321 tacagcacat gtaggggcag tagtagggct taaaagagag atgatagaaa ataacttaag
     7381 tgggactata gtattttatg catgtccagg agaagaacaa ttaacaggta aaggatttat
     7441 ggctagaggt ggagcgtttg aagggttaga cttagctata aattttcatc caaataaaat
     7501 tagtgaagct acaattggta cttcaacagc tgttaactct gtaaagtttc actttaaggg
     7561 aaagactgca catgcaggct cagaccctca aaatggaaga agtgcactag atgctgtgga
     7621 acttactaat gtgggagcta attatttgag agaacatgtt acttctgatg taaggattca
     7681 ttatacaatt acagatggag gagtagcacc caacatagtt cctgataaag catcagtatg
     7741 gtattataca agagctttaa gtagagaagc tgtagaaagt acatatgaaa gacttgtaaa
     7801 ggtagcaaaa ggagctgcaa tgatgactga aactgaagtt gaagtagaat ttttaggagg
     7861 atgttataat actttaaaca atcatgtttt agcaaatctt gtatcagaat gtatgaatga
     7921 gattaaacaa gagccttgga ctcgagagga attggatttt gcagctgaat tagatagaca
     7981 aagcccacaa caatataagg ctatgataag taaatataat ttgccagaag gaactcatct
     8041 atattatggt ggaggaaatg ttacaaactt taatagttat ggctctactg atattggaga
     8101 tgtaatgcat atagttccga cagcatactt ttttacaggg tgtacgaatc taggtgcacc
     8161 aggtcatagc tggcagttta catcttgtgc aggaagttct ataggagaaa aaggtatgat
     8221 atatgcatca aaaattatgg ctatgtttgg agctaaaata ttaaataatc cagagatagc
     8281 taaaaaggca aaagaagaat ttgataaatc tatgaatggt aaaacatata aatgtcctat
     8341 tccagatgat attccaactc cttaaaaaga catgaagttt aatatataaa attataattt
     8401 ttatatcagc atcatttcat tactaaaaga aagtgagatt ttgctgacta tctgattagg
     8461 aggaaggaat atgaaaaatt tttttaaaga agcgcagtca atagaagggg aaattattag
     8521 atggagaagg tatttacatg aaaatcccga aattggttgc aatctaccga aaacagtaac
     8581 ctttgttacc agtactttag aaaaaatggg atattctccg aaattgacgt ctaataatgg
     8641 aatagtagct gttttagaca gtgaaaatgg tggaaagacc ttattattaa gggcagatat
     8701 ggatgcactt cctattatgg aggagacgga tttacctttt aaaagtaaga ataaagatgc
     8761 atctcatagt tgtggacacg ataatcacac agcaatgctc ttaggagcag ctaaaatact
     8821 tatggataat aagcacttac ttaaaggtag agtaaagttt gtatttgaac cagatgaaga
     8881 gactaccaga ggtgcaaaat caatgattga tgatggtata ttagaaaatc ctcaggtcga
     8941 tgcagctatg gcatttcaca gtatggtggg taaatttctt aacacaggtc aagtagctta
     9001 ttcacgtggt ccagctatgg catctgcgga tatatttgaa ataacagtag aaggaaaagc
     9061 aactcatgga gcaagccctg aatttggagt ggacccaata aacataatgt cgcatataca
     9121 aatagcatta aacactatac tttcaagaga aaaacctcag aaagaacctg tagttttaac
     9181 tattggtatg tttaatgcag gaaacgtacc aaatgctata ccaaataaag catctatgtc
     9241 aggaacttta agaacatttg accaatttgt tagagaaaaa ttaaaaaata gaattattga
     9301 aatatctaca ggaatagcta aatcatttgg aggaaatgct aaagtggaat ttaaaatggg
     9361 gactcctgca gttataaatg atttggatgt aggagatgag attgtatctt atgttaaaga
     9421 agttatagga aatgaaaatg taatagactt tccatctgca atgggttcag aagatttttc
     9481 agagatttta ctaagggttc caggagtatt tttatggatt ggaatgggaa gtattagtca
     9541 gggatataat tttggtatgc ataatcctaa agcaattttt aatgaagagg gattagttta
     9601 tggttcagct ttatttgctc attgtgcagt aaaatggtta gaaaataatt ttagtagata
     9661 ataacataaa atattattaa atatcataaa aggtatatct taaaaagatg caaagatata
     9721 ccttttagaa agtcatatat aattttactt aatattagat gataaaatat ttttatgcat
     9781 tttggatttt aatatttatt ttctgatata aataatttgt ataccctttc aggtctacct
     9841 tttgttgagt tttgtttttc atataatata gtagcgtttc cagactttaa gagactactt
     9901 agaaatctat tagcagttct aactgttaca tttaaacatg aagataattc cttaggagta
     9961 acttcatctc tttgtagaat ttcagtaaca gatataatct tttgaatagt aagagtagac
    10021 aatttagaac ttttggcaat tgtatttata tgtggagtta ctttatttga aacagtaagt
    10081 aacttatcac acagtaaagg tcctattgtc tcataatttt cgttaactaa gaaactgtaa
    10141 tttaaaggat ttattttaga ttccttatta gcacttatgg cactagacat agcttgcttt
    10201 atatcattac caattccata tccaacacat actttaatat ttgtactatt ttcaatagat
    10261 tcttttatat aacatgcagt aaaattttta gttaatgatt taatcgtttc acatttagtg
    10321 aaaattttaa aagaattact atttttttca attataaaat cggttaattt atctttttta
    10381 atactattta atattttata aacttggtct agagtagagt catcataatt tgtatcttta
    10441 actgttatat atattacact tggttgattt cccttcattc tatgtaaatg aatatctttt
    10501 attaagttat taaaagtatt ttttaataaa tctatatcag ggtatatgaa atgaaagttt
    10561 actcctgcat tttgtaacat aggaacaata ctactaaaac gagtagtaga aaaatcgatt
    10621 ttcccttcat tccatagatt aatatgtttt tttgcaatct ttttttcaag ttttgctatg
    10681 tcagataaac tcattttaga tgcattttca tcaatactat ccattaagtc tccaaatgtg
    10741 ccatttgata aataatatga tatatctttt ggattatctg cccagtctgt taagtcaaag
    10801 tatgctctgg aaaaatctaa tgtattatat ttaaagataa gctttagaaa catatcatag
    10861 taactttgta agtcagtacc aaaatcaact agaggttttt ttatagttcc agcctttttt
    10921 gtaatagctt ttttggggat agggccacta actgcaaatc catcaaacct atcttctatt
    10981 tctaaatata aatctccaac atgagaaaaa tctctataga tatatatttt aatttctgca
    11041 ttaatattta acttttttat agaattatct acaaactctt ttaaaaattc ggttgttatg
    11101 actgctattt tcatcataga ttacttcctt ttcaattatt ataattattt tatattaaat
    11161 attacattaa tctattgttc tagttaaaat cgtatttcaa ttaaattcaa ttaaaataaa
    11221 taactcttta taaaaagcaa ttatttaggt agaggaatat ttgctaactt taatagtctt
    11281 tgttaacttt aattttattt aagttattat agtcttacta attttataat tgtagactta
    11341 actactttat gttcttttat tgtttatgta gttgatttag aagttatttt aaccatttat
    11401 tttaattgaa gttgtttgat ttttaaatcc tttgtgtaat ctttgttttt ctagccatga
    11461 taaaagtatt tctatttgta tcactatata taataatatc atgacaaaat atttattgtc
    11521 taactaatta taatctatcc aaaatgaaaa tgggtgtgag atattattac aacaaattgt
    11581 attagtatta aaaagattaa aaaattaaaa aactaaacag ttaaataatt aaacgattaa
    11641 gtgactgtca tataacaatt tataatttta tttaacagcc acttaggtat ttaagagcga
    11701 tagaattgag tgtatatcaa attataataa tttcctagta aataattgaa aaataaggta
    11761 gtccattttt atatttgata tctggtttac cttgaataag tggatataga taatttaggg
    11821 cttcatcagt tatataatta cattcttcat ttatccactc tttaggaaaa tattttgtct
    11881 tgttagctat tttagaaata tcagtatgac taacttcata cttataagga ttattgcatg
    11941 ttctattaat gatagccata actcctgtat atcctttttt agatagttct atcccatatg
    12001 caccaacttc agctgcttgt tttaaatcag tatatgaagc taaatgcata gcacatcttt
    12061 gtattacacc aagttctaag gtttttactc ttgttgtaat tgatgatgat actataagat
    12121 tctttagata gttgcttact ccacctaatt gggaatgacc aaatttatca tgagcagaag
    12181 ttttttgttc gcatataaag ttgccgtatt tatcccttat accttctgat gcaactatat
    12241 aagccttatt tttttcttta aatatttttc taacatcttc tataaactta tcttcataga
    12301 aatcaatttc tggaaggtat attaaatcaa caagtggagt atcattaagt ctagctagtg
    12361 aagaagaagc tgctaaccat ccagtatctc tacccatagt ttctactata aatataccat
    12421 tatttttgta tatagaaaaa tctaagtatg tttccattat tagtgtagaa ataagctttg
    12481 cagcagaacc aaatccagga cagttgtcag ttcctaataa atcattatct attgttttag
    12541 gaatacctat aaattttatt ttacaagtag tgtttttgca gtattgagaa aatttcatca
    12601 ctgtgtccat agaatcattt ccgcctatat aaaataatgt atctatttca tattcatcta
    12661 gtatatttat aaccctatca taatcataag aatttatttt ataatcagcc agtttgtatc
    12721 tacaagaacc aagaccagac gaaggtgttt gctttaaatt taatacatta tctttgttta
    12781 aggagtctga atctattata tttttgttta atataccttc aatcccattg ataccaaaat
    12841 atactttatc aaagtattta gtttctaaat ttttttcata aataccaact gcagaagcat
    12901 tgataacagc tgtagggcct ccagattggg caataataca gtttctcatt ttacatctcc
    12961 ctttcattaa tattgttatg aatggtactt tttatcgagt aaatttatat ttatagtctg
    13021 attatatatt aaatgaacta gctatatcaa ttgagttagt atagacaata aatgccataa
    13081 gaatgtggta aaaaactaac tttttatata caattaatgt ctataattta ccacaatata
    13141 aaggtacttt taaggagtag tcaaagtgtt gtgaaaaaaa atatatcagt gtaatattaa
    13201 tttacaaagc aaaataagtt cacagttaac aaaagcagaa taagttcata aaagaaatat
    13261 atacagcaat aaaagtaatg ctaaataaaa gtaatactgg attaaaaaat attaaaaaaa
    13321 tatcaaaaac taatatttaa tactaattaa agtaaaatat ggaggtatac aaatatgaaa
    13381 cacataaaaa tagcagcagg attagcacat gtaaattacg gtcatatatc agccgtagtt
    13441 aaagaagcaa tggatgcagg tgtagactac gtacattcag atgcagcaga tatgcatgac
    13501 ttaaaaaata tgcaacttat gggtggtcat caaataatag aagcaataag accagtgaca
    13561 gataaaccaa tagaatgcca tatatacaca agagattgtg atagattatt tatagaaaaa
    13621 atagcagcag caggatgtaa cttgttgata ataccagcag aacatttttt aggtgctcct
    13681 cttgcataca taataaatta ctgtagagaa tttggtatga aagtaggatt aacaattgga
    13741 tgttacacac cattatgttt tgttgatgaa gctatatatg atatagatag attgcaaata
    13801 gtcgttcatg gtgttgatga aactgatgga aaagataact ggggatggag aaagagtgct
    13861 gttgatttag taaaaagagc tagaaaaatg atagacgaaa agaatcctaa gtgtgaatta
    13921 gcaatagatg gtggactaag agcagacaat atggagccat taatagaatg taatccagac
    13981 gttgtaatat tatcttcagc aatattcaag gataaagatg gtataacagc aggtgttaag
    14041 aattgtagaa aagctataga tgaagcagct acaaagtttg gtttagaata agataataaa
    14101 ctatgataaa agagatgctt tcttaatgtt ttaaggaagc attaatttta tgaaaaacta
    14161 caggaagcta gactaattta attgattttt tatactgaaa caatataatc ataggaggtt
    14221 attaaatgaa aaaagaaatg ataaaagatt atttactgat aacaatatca gcatttttaa
    14281 tggcattagc agttaatttt ttctttgcag aacatacatt agctccagga gggataacag
    14341 gattatcagt cgtacttagc acattcttat caatgcctgt tgagaatata tcattaggaa
    14401 tatctatgcc acttttagta atgggattat tatttttagg gaaaggtttt ggaataaaaa
    14461 cattatatat aactcttatg ggcccattat tcttaaaagt aataccacaa actcacataa
    14521 ctgacaatct attagtagca ggagtgatag gtgggttatt ggtaggaact gctataggga
    14581 tagcaataat aaggggctgt agtactggtg gaactgattt agttgcaatg cttattaata
    14641 aggtaattaa gtttctgaag ttgccagtta tattatttat gctagatgga tttataatag
    14701 tagcgtctgg aataataagt aagaatttta tgatatctat atattcattg atatctttat
    14761 tactcataat aaaaacaata ggatttgtaa ctacaaagtt tggtaagaat actgaagaaa
    14821 ttaataatat aaataatgct tgtgctcaat aaaaataata aaatttactt taaatataaa
    14881 agtttaaaaa atataaaagc ttaaataaaa agattaaata taaaaaatga aggtgtctca
    14941 aaatgaattt tttagttcat gaggcacttt ttctatgaaa tcaaatatat ttttatcatt
    15001 tggacaatga aaaataggtt tatctctatg ttgagacaag cctatttttg tttatttata
    15061 agataatatt ttattttttt cagaatatag tttttttata attgtactaa gtctagaaat
    15121 atcattctta cttaaaagag catttatatt tatcagttca gcattatgtt caaagtctac
    15181 aggagcagta gttagtatta agtccacatc atcaaagttc gtaaatgaaa tagaagatag
    15241 aggtatagat ttaactatat taatctgatt aaattcaaaa cttaactttt ggactaataa
    15301 attagataca ccatcactac agtgacatat taaaatagta tttaggggag atttgcttct
    15361 atctattgct gatattaaat ataaagcaag atatcctatt tcgtcatcat tgacttcata
    15421 attcatcaac tgtttgataa cagtattaga ctctttagca gccttataag tataaggaaa
    15481 tgttctcttt atatcattta atatgggatt tgtaatagta aacccatagt ttattctgtg
    15541 tagaactgat ttaaggtgat tagcaagaga ctttattaat attaaatcat cctttaagtt
    15601 taagtttagt atacttcccc aatgaacagc tattgcttca gatagattat actctgtaat
    15661 ttcttcattt ttaagaggtt caagagtagt agttttcttt attgatttaa gtaatccttc
    15721 tatatgaaga aggatataac agacctcttc atcaataaat tctacgtcaa aagcttcact
    15781 taggttagca cataaaattt ttgatttttc aaagtattca tgttctaata attctctaaa
    15841 aaaaccttca gataagttaa tatatctttt aattgaaatt cttttaatac atatagctat
    15901 atgtattaag aagtttatat aatactcatc actaaggtta cttttttcta cttgtaaggt
    15961 gtgtagagtg atttgagata atttctcaaa atcatagtta aatagttcct taaatatttt
    16021 tgttgatggg gtatctttac attcattaga tttcgagaat aatatttctt taagttcagt
    16081 ataactttta ttaaccgtag caagttcaaa aattgctttt cgaatatctt tctcttttcc
    16141 ctctaaatat actccattat tggtttttct aactagagtc actttaaagt tttgcaaaaa
    16201 attttgaata actaccaagt ctttatgcac agtagctcta ctaacatgta gttcattgca
    16261 aatatcacga atcctaaact tagaattttt aataaataat ttacttagaa tatacctttt
    16321 tctatcttca ggagagtatg catatataca atttgattta tcattgatat ctctaataac
    16381 tttaagtttt atatcttcat tacctagaat aataacccct gaaccagttt ttttatctag
    16441 ggataaatta aactctaaaa gccattcatc taaaataaca aggtcattac gaatagtttt
    16501 attactaact tttaattctt cggcaatagt atctacagta atatagtctg agctgttgag
    16561 taataattca gcaatatcta ataatctttt gttcaatgca aaccctccta aatcttagtt
    16621 actatttatt aaccttggac caatctcttt caaaagtatt ggcaccatct attgtgagct
    16681 ggttaaaaga agctttttta aataaatcat atgttacagc tgcataatca catccacaaa
    16741 gagatgcttg agttaagtgg aatacatttt taatagaagc tgcaacaact ttagtattat
    16801 atccatttat tgatataagg ttacatattt ctgtaaggtt ttttatacca tcattcccat
    16861 tttcatcatt tctacctata aaagggaata ggtaatcagc acctgcattt atagctaatg
    16921 atgcttgatt tacattgaaa atcaaggtac atgcagtttt tacaccttta ctatttaata
    16981 tgtttataag ttctaagcca acttcagaga aatttatttt tattatagtg tttttattta
    17041 tatttaatat cttatcacat gaattaatta attcgtataa attatttcca atgacttcag
    17101 cagttaatat ttctggattt aaattagcac atgtctcaat aaattcatgg aagtttactt
    17161 tctctttaag atacatagat ggattagctg ttattccctt aaatccatac tttaaacact
    17221 tttgaatttc atcaagatta gcactgtcta tcaaatattt cataatttaa ttctccttta
    17281 agctatttgt cataaaaaag tgtatatact ctatttttat tattaagtca attatacaat
    17341 aagattgatt ataaaattat aacatgggta cttaataaaa tttacataat gatatggtaa
    17401 taataaaaca tttattgtct aataattgcc ataagcttta gtaaataaga gttaacagtg
    17461 aaggtattgc cttaaaaatc ctatgatatg tataatttga atatgaaggc aataatttaa
    17521 gggaggaaaa atatgattaa cttttatcaa ccatcaagaa taaattttgg acaaggaact
    17581 ttaagtgaat tacctagaat aataggaaaa tatggaaaga aatgtttgtt agttactact
    17641 ccaaatgtag agccattaga caagttatat aaaagagtta cattgaattt aatagaaaaa
    17701 ggtatagaag ttgtacactt tgattaaaaa atagctacgc acactcgtga ctttagtcat
    17761 gagttaatag ctaaaatagt cagcatatag ggaaacctat atgtagagat aggatagaac
    17821 ctatccaata ctacttgaat tgctggaaac ccctaaagct aaccaaacta aaacataagg
    17881 atgaaataaa cctaagtgtg aaagttacga aagtagaaaa aattggttag atggtataag
    17941 gttaaatcct aagtacttta aaatgggcaa tcagcaggta agctccgaat aggagaaact
    18001 tcaacgacta ttcctcttga gggaagtaca ctacaagtta t
//
LOCUS       DAMJXI010000073        16831 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.077, whole genome shotgun sequence.
ACCESSION   DAMJXI010000073 DAMJXI010000000
VERSION     DAMJXI010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16831
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.077"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            310..1122
                     /locus_tag="PC465_003085"
     CDS             310..1122
                     /locus_tag="PC465_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2650368.1"
                     /translation="MYLERPELYKQSEINFWDDEYISKQLLKAHLDTNFEGASRNFNF
                     IEDSVNWIVTVANPANYPKLLDLGCGPGLYAEKFAQKGYKVTGIDFSKRSINYAQNRN
                     KETNLNINYLFQSYLNMNYNEEFDLATLIYCDYGALSTENRRLLMEKIYDSLKPGGKL
                     ILDVFTINKYNNFEEIKYWEINEDGGFWSNEKYMCLQDNCKYNDYNTLEQTLVITEKD
                     ENVFYVWNHYFSKESFLLEVENIGFKSVEFFSNVKGEAYSDDSMTMGLVLQK"
     gene            2169..2930
                     /locus_tag="PC465_003086"
     CDS             2169..2930
                     /locus_tag="PC465_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896901.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HDF2650369.1"
                     /translation="MIGIYFSGTGNSRYCVEKFLQEYDITANSYSIEDNELLQHINNH
                     ENIIFSYPVQYSNVPKILKDFIINHSTLWNGKRVFIIATMALFSGDGSGVLARILKKY
                     GAITVGGLHVKMPDSIGDEKVLKHSLEYNRKLVIKAEKKVTKAAKKLKHGSPPKEGLG
                     FLSHIVGLFGQRLYFINKTNMYTDKLKINTEECIVCGKCVNLCPMKNLVIKNCMIVAN
                     GQCTMCYRCVNNCAKKAITLLGKKVVEQSNIKKYM"
     gene            2995..3777
                     /locus_tag="PC465_003087"
     CDS             2995..3777
                     /locus_tag="PC465_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HDF2650370.1"
                     /translation="MEYYIVDSFATKLFKGNPAGVCVLDRRIPLELMQKIAEENNLPE
                     TAFVVKGKGNYELRWFTPKAEIDLCGHATLAAAYVISNFIDVNVKRIDFFTQSGKLEV
                     TRNGNLYEMIFPEIMPIEIELSPQQANLIGCVPSAVYSSRDLILLLNSEQEVINYKPN
                     YAQLRKLTDWLGIIITAQGSNTDFVSRYFCPELDSEDPVTGSSHCNLIPYWSEKLGKH
                     KMVAAQLSNRGGIIQCEVLKDNTVKISGEAVLFMQGTIKIDI"
     gene            4044..4463
                     /locus_tag="PC465_003088"
     CDS             4044..4463
                     /locus_tag="PC465_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HDF2650371.1"
                     /translation="MDKISGKLTVLFEEPFWVGIFERQDGKKYEACRVVFGAEPKEVE
                     VYEFILERFFSLDFGSIKLEKNVTKDNIGYKRMQRKVKKEQEKETIGTKAQNALKLQY
                     EERKQDRKNLAKNRKEEEKERLFNLKQEKRKAKHKGH"
     gene            complement(4566..4832)
                     /locus_tag="PC465_003089"
     CDS             complement(4566..4832)
                     /locus_tag="PC465_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HDF2650372.1"
                     /translation="MKNFILIYFIVINSIAFFSMYIDKKRAIRNEWRIKEATLMSIAV
                     IGGSIGSIIGMYSFRHKTKHIKFTFGIPFILFLQFLLVYFYILK"
     gene            5059..5760
                     /locus_tag="PC465_003090"
     CDS             5059..5760
                     /locus_tag="PC465_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650373.1"
                     /translation="MKFIVEKEVFDKLENVCFGVVVAKGIDNTKEIERISNLLDISID
                     RVEDYFKDKKVKESEEIIPYREAFRSLGMNPNKFMSSIEAMTTRVAKNKKLPHINPIV
                     DLGNSISLKYLLPMGAHDMDFRNDDVYVRFSKKGDKFVPFGETDVELMEEGELIYSVG
                     DMVKTRRWIWRQGEEGKITNSSKNIFFPIDGFTDANLDKVMSAREELAKLLKEIFNCE
                     IKVGFVDKDNPEMEI"
     gene            5842..6450
                     /locus_tag="PC465_003091"
     CDS             5842..6450
                     /locus_tag="PC465_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF2650374.1"
                     /translation="MKKTIIKNVNPMIENKFIGLFEIEYKNKLDEDKVWMVASRKSSE
                     QLKNIYLKNEEDSVDAVVIVGLHKSSKKLILIRQFRVPINGYIYELPAGLVDEGESID
                     ISVERELREETGLTLLEIKKNKSIDKVYLSPGMSDESVAFVYCICDGDITDEFLEPDE
                     EIEALLISQEDAKEILQSNHKIDTKAFLILQMFVSLGAKLFE"
     gene            6774..7238
                     /locus_tag="PC465_003092"
     CDS             6774..7238
                     /locus_tag="PC465_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4624 domain-containing lipoprotein"
                     /protein_id="HDF2650375.1"
                     /translation="MKKLVISLISIISVVSLTACKKSNESKYNNLNNKESGQTTIEMD
                     LDKNYDTSDPFVNACLFCVSNDIDVLDTEISFKMDGDSGIVEIKDNKTDETLWSNIWH
                     GSVDNDTFAISLSNIQKEKEYAICFTGIKINHAVVKVTFESNLVKEKEKPSK"
     gene            7875..8891
                     /gene="gap"
                     /locus_tag="PC465_003093"
     CDS             7875..8891
                     /gene="gap"
                     /locus_tag="PC465_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDF2650376.1"
                     /translation="MKIKVGMNGFGRIGRAVLRIAQEELGDNIEIVAINARATTESLA
                     HLFTYDSCYGTFRGEVEAKDEDTLVVNSKEIKILRYNDPEELPWKELGVDIVIESTGL
                     FTQREKAEKHIKAGAKKVIITAPGKNEDITIVIGVNEKEYDNEKHNIISNASCTTNCL
                     APFAKVLDEKFGIVKGLMTTVHSYTNDQRILDKSHKDLRRARAAAESIIPTTTGAAKA
                     VSRVLPQLEGKLNGFSLRVPTPTVSLVDLVCELKENVTSEQVNSVLKDAAEGELKGVL
                     GYCDKPLVSIDYKGDSRSSIIDALSTMVIEDNMVKVVSWYDNEWGYSSRTVDLVKYVA
                     EKLK"
     gene            9286..10455
                     /locus_tag="PC465_003094"
     CDS             9286..10455
                     /locus_tag="PC465_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650377.1"
                     /translation="MEKLTDRRQVKAVSMETFIFLILLVVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLETVFLIMAMAVLAGALSALLSEFGVIALINKIFAVFMKPLYGLPGASIA
                     GAITTYLSDNPAIIPFAKDKTFTQYFKQYQVPALCNLGTAFGMGLILTTFMISQGTEY
                     VLPALIGNLGAIIGSVISVRIMLTFTKKFYKYNPEEDKATGTLEKKDEFREIREGNVF
                     QRALDAILEGGKMGVDMGMAIIPGVLVVCTLVMLLTFGPSTDPVTGQEVYTGAAYEGI
                     KLLPVIGDKLGFILEPLFGFTSPEAIAFPITSLGAVGAAMSLVPEFIKSGAITPNDIA
                     VFTAMGMCWSGYLSTHIGMMDALNARQLAGKAILSHTIGGLCAGAAAHFIFTLVG"
     gene            10836..15089
                     /locus_tag="PC465_003095"
     CDS             10836..15089
                     /locus_tag="PC465_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HDF2650378.1"
                     /translation="MDELFHIGIDVGSTTVKVVVLNNSNNIVHKEYRRHYSDVKKSVK
                     EVLNGIYEKLGDINTTIIITGSGGIGISKKLGVKFVQEVISSTKSIEYFHPETDVVIE
                     LGGEDAKITYLSGGIDQRMNGICAGGTGAFIDQMASLLKTDASGLNELAKGYNVIYPI
                     ASRCGVFAKTDIQPLINDGANQTDIAMSIFNAVVVQTVSVLSCGRKIEGNVAFLGGPL
                     YFLSELREAFKRVLDLKDENIIFPENAQLYIAIGAGLLSVDEDNIQLKSLIEKLDSIK
                     NIEDGEVNLLEPLFKDKNEYEEFSRRHEKEKINYVDINSIKSNCYLGIDAGSTTTKAA
                     LIDEDGRLVYSYYNSNEGNPLKTTIKVINEVYDILPKNIKILSSTVTGYGEGLIKKAL
                     KIDNGEIETIAHYKAAKFFNKDVDFILDIGGQDMKCLKIKDGVIDNIILNEACSSGCG
                     SFLETFASSLSMTIEEFAHEGIYSQNPVDLGSRCTVFMNSRVKQAQKEGASVGDISAG
                     LSYSVIKNALFKVIKIRDLNEIGNNIVVQGGTFYNDLVLRSFEKLIGKNVIRPNISGI
                     MGAFGSALIAKEKYESGYKTSLLSKEELNNIKLEASVTRCKGCSNHCLLTINKFSDNE
                     IFISGNRCEKGEAIYGDKKIGLEKKKPINLFKYKYNRIFRYKPLEKEEAKNGEIGIPR
                     VLNMYEDYPFWFTFFNAMGFRVVLSDRSSKQLYETGITSIASETVCYPGKLVHGHIEN
                     LIAKGIKNIFYPSVTNENKEDSNADNYYNCPVVISYSEVIKNNVENIRNKNINYINPF
                     ISLNDKEKLKKRLYDELSRHFSDIKITKEEVNHAVDKATEEQNLFKMEIQAAGERALK
                     EIKERNMKGIVLCGRPYHIDPEINHGMPELINSLDMAVLTEDSICHLANVQRPLRVVD
                     QWVYHSRLYKAASFVRDKNYLELVQLNSFGCGLDAVTTDQVQEILNEKSKIYTIIKID
                     EGNNLGAAKIRMRSLKAAMFERESKNIDVKNIKVNRIQYAKNNQITNKHTILAPQMSP
                     IHFQFLEKAVNLSGYNIEILKDTDSSVIEEGLRYVNNDACYPAIIVVGQLITALKSGK
                     YDLNNTSVTITQTGGGCRATNYIGFLRKAIYDAGFKDVPVIALSVNGIEDSGIMDNIS
                     LKLINRLFMSVVYGDLLMKVLYRVRPYEKVTGSANALYEKWVDICKSSLVKAKISVFT
                     RNIKDIVKEFDNLEILDIKKPKVGLVGEILVKFHPIANNNLVDILEREGAEAVVPDLT
                     NFFLSCAFNTIYKHTHLEGSRKSRMIGEAFIYITGIYQRVYKKALDKSERFYAPANIK
                     NVAKSTEPVVSLGNQTGEGWLLTGEMVELLNEGVENIICMQPFGCLPNHIIGKGSIKE
                     LKRLYKNANIIPIDYDPSASEVNQLNRIKLMLSKAFKNI"
     gene            15238..15732
                     /locus_tag="PC465_003096"
     CDS             15238..15732
                     /locus_tag="PC465_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDF2650379.1"
                     /translation="MSLVYDVYKSKLGNLYILSEDGFIVSIYIGDEKFNNLKNECIKK
                     GIDIKRSKEDLKEAISQIDDYFNGKRKVFNLNIRIEGTEFQKSVYREMLKIPYGETLC
                     YSDIARNINNPKSVRAIGQASKSNKIPIIIPCHRVVGKKDIGGYMGNHSDLKEILLNL
                     ERQS"
     gene            15848..16225
                     /locus_tag="PC465_003097"
     CDS             15848..16225
                     /locus_tag="PC465_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HDF2650380.1"
                     /translation="MCDKVIASKYHEKGFNCAESVIKAYNEEFNTDIPVCLGSGLGSG
                     CGVASLCGAVNASNIIIGYVKGRNHEDESTKAKVYAKDLTTTVRKEYGSELCIDLKKD
                     LVACREIMDFAYDSLKETLKKEL"
     gene            16431..>16831
                     /locus_tag="PC465_003098"
     CDS             16431..>16831
                     /locus_tag="PC465_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufBD protein"
                     /protein_id="HDF2650381.1"
                     /translation="MKNLNLLINKLYSKNHNEAYKTFLFLENESLKSNITYCFFDSFL
                     EMIDNENSYIRTRGLLLISANAQWDIDNKIEINIDSILSHIVDKKPSVSRMFIKSIPN
                     ITKYKENLINRIKMELSNADISIYNNNMKPLV"
BASE COUNT         6857 a         1633 c         2929 g         5412 t
ORIGIN      
        1 tgacaaatat aaaatttaaa tatataatta attcataaaa taaaaatatg aaaggatgat
       61 gttgttcggt gatatttgat atcataaaat cgttgatata agtattgctg gaaaagagtg
      121 aataaaatca aatttaataa gcaaacaaag taaagctata gttttattgt tgtgcttaaa
      181 aatatttggt tctattttac tcttatttaa actcatcttt ttgaagttaa accacagagt
      241 aaactctgtg gtttttttat tttaaaaata aattttaagg agtggtatgt tttgttaaac
      301 aaattatgta tgtatttaga aagaccagag ctttataaac aaagtgaaat taatttttgg
      361 gatgatgagt atatttcaaa gcaattatta aaagcacact tagacactaa ttttgaagga
      421 gcaagtagaa attttaactt tatcgaggat tctgtaaatt ggatagttac agttgcaaat
      481 ccagctaatt atcctaaatt acttgattta ggttgtggtc caggtttata tgcagagaaa
      541 tttgcacaaa aaggttataa ggtaactgga attgatttct caaaacgttc tattaactat
      601 gcacaaaata gaaataagga gactaattta aacataaatt acttgtttca aagttattta
      661 aatatgaact ataatgagga atttgatttg gctaccttaa tttattgtga ttatggagct
      721 ttgtcaactg aaaatagaag gttattaatg gaaaaaattt atgatagttt aaaacctgga
      781 ggaaaattaa tattagatgt atttacaata aataaataca ataattttga ggaaattaaa
      841 tattgggaaa taaatgaaga tggaggattt tggagtaatg aaaaatatat gtgtctacaa
      901 gataattgta aatacaatga ttataataca ttagaacaaa ctcttgtaat aaccgaaaaa
      961 gatgaaaatg tattttatgt ttggaatcac tatttttcaa aagaaagttt cttattagaa
     1021 gttgaaaata ttggatttaa gtctgttgag ttttttagta atgttaaggg tgaagcatat
     1081 tctgacgata gtatgactat gggattagtt ttacaaaaat aataattttt ttaaaatgaa
     1141 taaataaaaa cttgaaacct ttaacaataa aataacataa taaaagctta catattgaaa
     1201 aatggaaact tttatgttat ttttagtaca ttacaaattt gcttatataa aaatcaatac
     1261 ttgaattatt atttttatgt gaaatttatc tatagtatat ttttataaac aagtaatgtt
     1321 attaaaatta agtatatagt taaaagtgta tagcaaaaag gctgttatat taatgttaga
     1381 ggttcaggga aaatatataa agcaaagtat ttacagataa tgtagattgc acagctataa
     1441 gttagataat agaattatgt aatcaagaat ttacaacaaa gtataagata aggataatgc
     1501 taaattgcca tacaggtgct agatgtgtaa atggatttaa ttaatactat tgataaagtg
     1561 caacaagcac ataaaccaat tgatgagatt attaaaacta taagagatat agttgacata
     1621 attaaaatat tggaacctat ttataatttt aaatcaaatc aataatgatt aagattaaaa
     1681 taatattaag gcatcaatgt tataagagta caatataagg agtactatat agtactcctt
     1741 acttatacat attaggcaat aggaaatttt tcatagttaa attttcaaat attttttagg
     1801 gaactttata attgagaatt aagggtatag tatgtgatga acttactaaa tttataatta
     1861 ggttatataa tggaataatc atcaatagtt ttactttagg gaaaatatat gcttaaggaa
     1921 gtatagctta ctaatattat taaaatgtat atttaaaatg ataaaaaaag aattagacaa
     1981 gtatttagta aattgactat gcaaaattct atcaagcagg aacactatga ctttagtcat
     2041 gggaggttca gtaggtaact tgttgaatta agtttatatt atttaaataa actacttaat
     2101 ttagataata taaaaagtca gaattttaag aatagagcta tataatctta gctattagga
     2161 gaagtactat gataggaata tattttagtg gaacaggaaa ttcaagatac tgtgtagaaa
     2221 aatttttaca agaatatgat ataacagcaa attcttattc tattgaagat aatgaacttt
     2281 tacagcacat caataatcat gagaatatta tttttagtta tccggtgcaa tatagtaatg
     2341 tgccaaaaat attgaaagat tttataataa atcattcaac tttgtggaat ggtaaacgtg
     2401 tttttattat tgcaactatg gctctattta gtggagatgg ctctggtgtg ttagctagaa
     2461 tattaaaaaa atacggtgct ataactgttg gtggattaca tgtgaagatg ccagatagta
     2521 taggagatga aaaggtatta aaacattctt tagagtataa tagaaagctt gtaataaaag
     2581 cagaaaagaa agtaactaag gctgctaaaa aactgaaaca tgggtcacca ccaaaagaag
     2641 ggttgggttt tttgagtcat attgtagggt tatttggaca acgattgtat tttatcaata
     2701 aaacaaatat gtatacagat aaactaaaaa ttaatactga ggaatgtatt gtatgtggta
     2761 aatgcgttaa tttatgtcca atgaagaatc tagtaattaa aaattgtatg attgttgcaa
     2821 atgggcaatg tacaatgtgt tatcgttgtg taaataattg tgccaaaaaa gcaattacat
     2881 tgttaggtaa aaaagttgtt gaacagagta atattaagaa atatatgtaa gaaatttaaa
     2941 gttttattga atgtaaattg atgtatattt tatgttagaa agagaggtta aataatggaa
     3001 tactacatag ttgattcatt tgcaactaaa ctatttaaag gaaatcctgc tggagtttgt
     3061 gttcttgaca gaagaatacc tttagagtta atgcagaaaa tagcagaaga aaacaattta
     3121 ccagaaacag catttgtagt taaaggtaaa ggaaattatg aattacgatg gtttactcct
     3181 aaagcagaaa ttgatttatg tggtcatgca actttagcag cagcttatgt aatatcaaat
     3241 tttattgatg ttaatgtaaa aaggatagat ttctttactc aaagtggaaa gcttgaagtt
     3301 acacgaaatg gaaatctata tgaaatgata tttccagaaa taatgcctat tgaaatagag
     3361 ttatcaccac aacaagctaa tttgataggc tgtgtaccaa gtgctgttta ttcttcaaga
     3421 gatttaatct tattgctaaa cagtgaacaa gaagttataa attataaacc taattacgca
     3481 caattgcgta aattgacaga ctggttaggt ataataatca cagcacaagg aagtaataca
     3541 gattttgtat caagatattt ttgtccagaa ttagattcag aagaccctgt tactggttca
     3601 tcacattgta atcttattcc atattggtct gaaaagttgg gaaaacacaa aatggtagct
     3661 gctcaacttt ctaatcgtgg tggtataatt cagtgtgaag tgttgaagga taatactgta
     3721 aaaatttctg gtgaagcagt cttgtttatg cagggaacaa taaagattga tatttaaata
     3781 agtataataa ctaatttatt atgaaaaata attaattttc ttagtgttaa caataataaa
     3841 gtagagttaa aaaacttgat ttcacttaaa tcaatatgat agatgttgat actaagattg
     3901 acaagcatga ttaaaaaaga taatatttaa tctataaaga taaaaacaca gtctggttgg
     3961 tagtccagac gcagcaatag ctgtcagtaa cctgcctcct tggttgtccg ttctttagaa
     4021 agtaatttaa ggaggaacta gcaatggaca aaattagtgg aaaattaaca gtcttatttg
     4081 aagaaccatt ttgggtaggt atatttgaaa gacaagatgg taaaaaatat gaagcatgta
     4141 gggtagtttt tggagcagaa cctaaagaag tagaagtgta tgaatttata cttgaaagat
     4201 ttttctcatt agattttggt agcattaaat tagaaaaaaa tgtgaccaaa gacaacattg
     4261 gatacaaaag aatgcagaga aaagtaaaaa aggaacaaga aaaagaaact atagggacta
     4321 aggctcaaaa tgctcttaag cttcaatatg aagaaagaaa acaggataga aaaaacctag
     4381 ctaaaaatag aaaagaagaa gaaaaagaaa gactatttaa tttgaaacaa gaaaagagaa
     4441 aagctaaaca taagggtcat taattttaat taaatatctt tttaataatt gctagaaaaa
     4501 ggtgtataaa atttttaatt ttatacacct taatttattg aaaagaataa ggttttatat
     4561 ttcaattact ttaaaatata aaaatatact aataaaaatt gtaaaaatag tataaatggt
     4621 ataccaaatg taaatttaat gtgtttagtt ttatgtctaa aagaatacat tccaattata
     4681 gaacctatac tacctccaat tactgctata gacataagag tagcttcttt tattctccat
     4741 tcgtttctaa ttgctctttt cttatctatg tacattgaaa agaaagcaat agaattaatc
     4801 actataaaat atattagaat aaaatttttc acagtcttgc ctccataaaa atatattata
     4861 cattataaaa caagatattt gttttggaaa gttaaatttg taattagtac atataaaata
     4921 tttgataaga ataaatataa tattaattgg aaaatttaaa aaaattaaac aattagcaaa
     4981 tagggggtat atttataaga cacaaagtga taaaatctat ttagaaaata atgtaaaata
     5041 acaggaggat aaagcaaaat gaaatttata gtagaaaaag aagtttttga taaattagaa
     5101 aatgtatgct ttggtgtagt agttgcaaaa ggaatagata atactaaaga aatagaaaga
     5161 ataagcaacc ttttagatat aagtatagat agagtagaag attacttcaa agataaaaaa
     5221 gtaaaggaat cagaagaaat tataccatat agagaggcat ttagaagtct aggcatgaac
     5281 ccaaataaat ttatgagttc gatagaagca atgacaacaa gggttgctaa gaataagaaa
     5341 cttcctcata taaatcctat tgtagattta ggaaactcta tttctttaaa atatttactt
     5401 ccaatgggcg ctcatgatat ggattttaga aatgatgatg tatatgttag attttctaaa
     5461 aaaggggata aatttgtacc atttggagaa actgatgttg aattaatgga agaaggagaa
     5521 ttaatttatt cagttggaga catggtaaaa actagaagat ggatatggag acaaggagag
     5581 gaaggaaaaa ttactaatag ctcaaaaaat atattttttc ctatagatgg ttttactgat
     5641 gctaatttag ataaggtaat gagtgcaaga gaagaattag caaaattgtt aaaggaaata
     5701 tttaattgtg aaattaaagt aggttttgta gataaagata atcctgaaat ggaaatataa
     5761 taagttgttg aatacttgtt aagatattat atttacttaa taatgttaaa aaggtattaa
     5821 aaaagaaagg tcgtagtaaa tttgaaaaaa actataataa agaatgtaaa tccaatgatt
     5881 gaaaataagt ttataggact ttttgaaata gagtataaaa acaaattaga tgaagataag
     5941 gtttggatgg tagcatcaag aaaaagtagt gagcaattaa aaaatattta tttgaagaat
     6001 gaagaagata gtgtagatgc agttgtaata gttgggcttc ataaaagtag taaaaaatta
     6061 attttaataa gacaatttag agtacctatt aatggatata tatacgagtt accagcaggt
     6121 cttgttgatg aaggagagtc tatagatatt tccgttgaaa gagaacttag agaagaaaca
     6181 ggacttactc ttttagaaat taaaaaaaat aaaagtattg ataaagttta tttatctcct
     6241 ggaatgagtg atgaatctgt tgcctttgtt tattgtatat gtgatggtga tataacagat
     6301 gaatttttag aaccagatga agagattgaa gcgcttttaa tttcgcaaga agatgcaaaa
     6361 gagattttac aaagtaatca taagatagac acaaaagcat ttttgatttt acaaatgttt
     6421 gtgagtttag gagctaaatt atttgaatag atatatagaa aagaggttat atagaagagt
     6481 aaaataataa agtttatttt acttgtataa attataatct ctttttttat acaataaagt
     6541 ataattttgt gtatttttaa ataagtgact tgactcttaa attttcataa tatgttataa
     6601 accaatttaa gatactacaa taattaaaat tccaaaatta tttaacatat ttgcaattaa
     6661 aatgagaaaa ggtaaaggct gaatgattga aaaatttgat gtaaaatagt agattagttt
     6721 aatactatag tttgtagggt taaaaattag aaattgtaag ggagataaat tctatgaaaa
     6781 aattagttat tagtttaatt agtatcatta gtgtggttag cttgacagct tgtaaaaaaa
     6841 gcaatgaaag taaatataat aatttaaaca acaaagaatc aggacaaaca accattgaaa
     6901 tggacttaga taaaaattat gatacttcag acccatttgt taatgcatgt ttgttttgtg
     6961 tgtctaatga tatagatgtt ttagacacag agatttcttt taaaatggat ggagatagtg
     7021 gtattgtgga aataaaggac aataaaacag atgaaacttt atggagtaat atatggcatg
     7081 gaagcgttga taatgataca ttcgcaattt ctctttctaa tatacaaaaa gagaaagagt
     7141 atgctatatg ctttactgga attaaaataa atcatgcagt tgtaaaggtt acttttgaaa
     7201 gcaatttagt taaggagaaa gaaaaaccct caaaataaat tccagattgt ctataacttg
     7261 atattcagta cataaaagca gttgatattt atgattgact gctttttctt atcaaaaagg
     7321 ataggttgtg catttttact tgaaatagtt tatgcacatc aaaagttggt gagcatgata
     7381 ttggaaatgg taagcatgaa atcttgataa cacaaggaaa taaatttaag ttttcaatta
     7441 agtatatttc cataatttag ttaacaataa gctaattatt atttatattt tgatatataa
     7501 ataataattg tagcaaattt taaaaaatca tatatttttt gaactaaata aaaatttatt
     7561 tttattattt taaattagag gagattcttg aagatatatt atttttaaaa ataagtatag
     7621 tttaaaaatt caaaaaaaag atggcaaaat atgtcccaag ggacattgag taaaataaat
     7681 gatttcagct tctttacact aaaaagtaca tactaaatga ggggtaaaat aaagaaaaat
     7741 gatatactaa ttgtcttttg ataataaaaa aacatggaat ttgattattt aatcaagaaa
     7801 aagtattgaa caaatgattt atttagtgta caataatcat gtaaaaacat agtaatggag
     7861 ggagacattt cataatgaaa attaaggtag gaatgaacgg atttggaaga ataggaagag
     7921 ctgtattaag aatagctcaa gaagaattag gagataatat agaaattgta gccataaatg
     7981 caagagcaac aacagaatct ttggcacatt tatttacata tgattcatgc tatggaactt
     8041 ttagaggtga agtagaggca aaggatgaag acactctagt agtaaactct aaagagataa
     8101 aaatattaag atataatgac ccagaagaat taccttggaa agaattgggg gttgatatag
     8161 taatagaatc aacaggatta tttacacaaa gagaaaaggc agaaaaacat attaaagcag
     8221 gagcaaaaaa agtaattata acagctccag gaaaaaatga agatataact atagttatcg
     8281 gagttaatga gaaagaatat gataatgaaa agcacaatat aatttcaaat gcatcttgta
     8341 ctacaaattg tctagctcct tttgctaaag tattggacga aaaatttggt atagtaaaag
     8401 ggttaatgac tacagtacat tcatatacta acgatcaaag aatattagat aaaagccata
     8461 aagatttgag aagagcaaga gcagcggctg aatctataat acctaccact acaggagcag
     8521 caaaagctgt gtcaagagta ctaccacaat tagaaggaaa attaaatggt ttttcactta
     8581 gagtaccaac accaacagtt tcacttgttg atttagtgtg cgaacttaaa gaaaacgtta
     8641 catctgagca agttaactct gtgttaaaag atgctgctga aggagaatta aaaggtgttt
     8701 taggatattg tgacaagcca cttgtttcta tagattataa aggagattca agatcatcta
     8761 ttatagacgc tctatccaca atggttatag aagacaatat ggttaaggta gtttcttggt
     8821 atgataatga atggggatat tcttcaagaa ctgttgactt agtaaaatat gtagctgaaa
     8881 aattaaaata atatatattt cttaaagcaa attttaaaaa aattttttaa aaaaaatata
     8941 taaaactaaa aaaaaagatt atgaaaaata ttgaaggaaa aattttttca taatcttttt
     9001 tctttcatgc aaaaagatac aagttacaac ttatatttgc atattaggtc gttagagaag
     9061 tatatatata tttagtaagg aatcatactt tttataaaat gaaagataag atgtcgaaaa
     9121 cttgcataaa tctgaaaaat ttttattatt aaaatactga tttccatttt aaaaatgata
     9181 aaaaaatgac aaataaagtt gcaaatagta atacttataa gtataattaa aaaagagaaa
     9241 aggttttgtt aaactttata acaaaaaaag aagggatgat tcaaaatgga gaagttaaca
     9301 gacaggagac aggttaaggc agtaagcatg gaaaccttca ttttcctaat attactagta
     9361 gttggttttg ggtatgttgg tagtattatg ggagcaggaa tgatgttcaa agtaataatg
     9421 agtacagcac atgctttact attggagaca gttttcttaa ttatggctat ggcagttctt
     9481 gcaggcgcat taagcgcact actttcagag tttggagtaa tagcgttaat taataaaatt
     9541 ttcgctgtat ttatgaagcc tttatatgga ctacctggtg ctagtatagc aggagctata
     9601 acaacttatt tatcagataa tccagctatt ataccttttg ctaaagataa aacattcaca
     9661 cagtatttta aacaatacca agttccagca ttatgtaact taggaacagc ctttggtatg
     9721 ggacttatct taacaacatt tatgatttct caaggtacag aatatgtact tccagcatta
     9781 attggtaatt taggtgcaat tataggtagt gtcataagtg ttagaataat gttgacattt
     9841 actaagaagt tttataaata caatccggaa gaagataaag caacaggaac attagagaaa
     9901 aaggatgaat ttagagaaat cagagaagga aatgtatttc aaagagcttt agatgcaatt
     9961 cttgaaggtg gtaaaatggg ggtagatatg ggaatggcta taattcctgg agtcctagta
    10021 gtatgtacat tggtgatgtt attaactttt ggaccatcta cagaccctgt tacaggtcaa
    10081 gaagtttata caggagctgc atatgaagga ataaaattac ttccagttat tggagataaa
    10141 cttggattta tattagaacc attatttgga tttacatcac cagaggcaat agcattccct
    10201 ataacttcat tgggagctgt tggtgcagca atgtctctag ttccagagtt tataaagtca
    10261 ggagctataa ctcctaatga tatagcagta tttacagcta tgggtatgtg ttggagtgga
    10321 tatttaagta cacatattgg tatgatggat gcattaaatg ctagacagtt ggcaggtaaa
    10381 gctattcttt ctcatacaat aggtggttta tgtgcaggag cagctgctca ctttatattt
    10441 acactcgtag gataaatgta atcagctaag ataaaaaata atatacaaaa aaatggttgt
    10501 tgatatgtaa taagaattta catatcaaca accatttttt tctgactaaa gataatttat
    10561 aatacataaa cattaagtgg atattagagt taagttatat ttatgtaaaa agtaacaaaa
    10621 atctgtagaa atttatgaca aaatttagta cactaactat atgttcttat ttaaaattta
    10681 aggttagaat taggaattac ctagtagagt aagctttgat taataaaaga atcataaaat
    10741 aaaaatatta gtcataaaga ttataaataa cttacttaaa ataaagccat agaacttaca
    10801 aaaattaaaa aagcatataa atatggaggg gtacaatgga tgaattattt catataggaa
    10861 ttgatgtagg ttctacaacg gtgaaggttg tggtacttaa taatagtaat aatatagttc
    10921 ataaagaata tagaagacat tattctgatg taaaaaaatc agttaaagaa gtactaaatg
    10981 gtatatatga aaaattggga gatataaata ctaccattat aataactggt tcaggtggaa
    11041 ttggaatatc aaaaaaatta ggtgtaaaat ttgttcagga agttatatct agtacaaaat
    11101 caatagagta ttttcatcct gagactgatg ttgtcataga acttgggggt gaagatgcaa
    11161 agataacata tctaagtgga ggaatagacc aaagaatgaa tggaatatgt gcaggtggca
    11221 ctggagcatt catagaccag atggcatcac ttttaaagac agatgccagt ggattaaatg
    11281 aacttgctaa agggtataat gttatatatc ccatagcttc aagatgtggt gtttttgcta
    11341 aaacagatat tcaacctctt ataaatgatg gagccaatca gactgatata gcaatgagta
    11401 ttttcaatgc agttgtcgta caaactgtga gtgtcctttc ttgtggaaga aaaatagaag
    11461 gaaatgttgc gtttttgggt ggtccattgt actttttatc tgaacttaga gaagcattta
    11521 aaagagtatt ggatttaaaa gatgaaaaca taatcttccc agaaaatgca caactttata
    11581 ttgctattgg cgcaggatta ttatcagtag atgaagataa tatacaacta aaatctctaa
    11641 tagaaaaatt ggatagcata aagaatattg aagatggaga agtaaattta ttagaacctt
    11701 tatttaaaga taaaaatgag tatgaagaat tttcaagaag acatgaaaaa gaaaaaataa
    11761 attatgtgga cataaattca ataaaaagta attgttattt aggaattgat gcaggctcaa
    11821 ctacaactaa agcagcactt attgatgagg atggaagact tgtatattct tattataata
    11881 gcaatgaagg aaatccatta aaaacaacca ttaaagttat aaatgaagta tatgatatat
    11941 taccaaaaaa tattaaaata ttgagttcaa ctgtaactgg atatggagaa ggtcttatta
    12001 aaaaagctct taaaatcgat aacggagaga tagagactat agcacattac aaagctgcta
    12061 aatttttcaa taaagatgta gattttatac ttgatattgg tggtcaagat atgaagtgcc
    12121 taaaaataaa agatggagta attgataata taatattaaa tgaggcttgt tcatcaggtt
    12181 gtggctcatt tttagagaca tttgcaagtt ctttatctat gacaatagaa gaatttgcac
    12241 acgaaggtat ttattctcaa aatcctgtag atttaggttc aagatgtact gtatttatga
    12301 attctagagt aaaacaagct caaaaagaag gtgcaagtgt tggagatata tcagcagggc
    12361 tatcttattc agtaataaaa aatgctttat ttaaagtaat aaagattaga gatttaaatg
    12421 agattggtaa taatattgtt gtacaaggtg gaacctttta taatgatttg gtgcttagaa
    12481 gctttgaaaa actaattgga aaaaatgtaa ttagacctaa tatttcagga attatgggag
    12541 cttttggttc agcacttata gctaaagaaa aatatgaaag tggatacaaa acatccttgt
    12601 tatctaagga agagttgaat aatatcaagc tagaagcaag tgtaactaga tgtaaaggtt
    12661 gttcaaatca ttgtcttctt acaataaata aattttctga taatgaaatt tttatttcag
    12721 gtaatagatg tgagaagggt gaagctattt atggtgataa aaaaatagga ttagaaaaga
    12781 aaaaaccaat aaatttattt aagtacaaat acaatagaat ttttagatat aaaccattgg
    12841 aaaaagaaga agcaaaaaat ggggaaatag ggataccaag agtattaaat atgtatgaag
    12901 attatccatt ttggtttact tttttcaatg ctatgggctt tagagttgta ctttcagata
    12961 ggtcatcaaa acagttatat gaaactggta taactagtat tgcatctgaa acagtttgtt
    13021 atccaggaaa attagttcat ggacatatag aaaatttaat tgcaaaaggt ataaaaaata
    13081 tattttatcc aagtgtaaca aatgaaaata aagaggattc aaatgcagat aattattata
    13141 attgtcctgt tgtaatatca tattctgaag taataaaaaa caatgtagaa aatataagaa
    13201 ataagaacat aaattatata aatccattta taagtctaaa tgataaggaa aaattgaaga
    13261 aaagactata tgatgaatta tcaagacatt tttctgatat aaaaataact aaagaagaag
    13321 ttaatcatgc agttgataaa gctactgagg aacagaattt atttaaaatg gagatacaag
    13381 cagcaggtga aagagcactt aaagaaataa aagaaagaaa tatgaagggg attgtgttat
    13441 gtggaagacc atatcatata gacccagaaa taaatcatgg aatgccagag cttataaatt
    13501 cattagatat ggcagtgctt actgaagact ctatatgtca tttagccaat gtacaaagac
    13561 cacttagagt tgtagaccaa tgggtatatc attcaagatt gtataaagca gctagttttg
    13621 tgagagataa aaactatttg gaacttgttc aacttaattc atttggctgt ggattagatg
    13681 cagtaactac agaccaggtt caagaaatac ttaatgaaaa atcgaagata tatactatta
    13741 taaagattga cgaaggcaac aatttaggag cagctaagat aaggatgagg tccttaaaag
    13801 cagctatgtt tgagagagaa agcaaaaata tagatgtaaa aaatataaag gtaaacagga
    13861 tacagtatgc taaaaataat cagataacga acaaacatac tatattagca ccacaaatgt
    13921 ctccaataca tttccaattc cttgaaaaag ctgttaactt aagtggttat aatatagaaa
    13981 ttctaaaaga tactgatagt agtgtaattg aagaagggtt aagatatgta aataatgatg
    14041 catgttatcc agctataata gttgtaggtc agctaataac agcattaaaa tctggcaaat
    14101 atgatttaaa taacacttct gttactataa ctcagactgg tggaggttgt agagctacaa
    14161 attatattgg attcttaaga aaggctatat atgatgctgg atttaaagat gttcctgtca
    14221 ttgcacttag tgtaaatgga atagaagata gtggtataat ggataatata tcactaaaat
    14281 taatcaatag actctttatg tctgttgttt atggtgattt gctgatgaaa gtactatata
    14341 gagtaagacc atatgaaaaa gttactggaa gtgcaaatgc tctatatgaa aaatgggttg
    14401 atatatgcaa atcttctctt gttaaagcaa aaatttctgt atttactaga aatataaaag
    14461 atatagtaaa agaatttgat aatttagaga tactagatat caaaaaacca aaagtaggtt
    14521 tggttggaga aatattggtg aaattccatc caattgcaaa taataattta gtagatatat
    14581 tagagcgaga aggtgctgaa gcagtcgtgc cagaccttac aaatttcttc ttaagttgtg
    14641 cctttaatac tatatacaaa cacactcatt tagaaggaag tagaaagagt agaatgatag
    14701 gagaggcatt tatatacata actggaatat atcaaagagt atataaaaaa gcacttgata
    14761 agagtgagag attttatgct ccagccaata taaaaaatgt tgctaaaagt acagaaccag
    14821 tagtgtcatt aggtaatcaa actggagaag gttggctttt aacaggtgaa atggttgaat
    14881 tattaaatga aggtgtagaa aacattattt gtatgcaacc ttttggatgt ttacctaatc
    14941 acataattgg taagggttct ataaaagaat taaagaggtt gtataaaaat gcaaatataa
    15001 tacctattga ttatgaccct tctgcaagtg aggtaaatca acttaacagg ataaaactta
    15061 tgctttctaa ggcttttaaa aatatataag atttatattt tgatatgtta aaagttaatg
    15121 aatttaaaaa tatactctat attaagtatc tataaaaaag agttatccta ttttttaggg
    15181 taactcttta ttagttaaaa aattatatgt atactgatat taaagggggg aagtaatatg
    15241 agtttagtat atgatgttta taaatcaaaa ttaggaaatt tgtacatatt aagtgaagat
    15301 ggttttatag ttagtatata cataggagat gaaaaattta ataatttaaa aaatgaatgt
    15361 attaaaaaag gaattgatat aaagagaagt aaggaagatt taaaggaagc aataagccag
    15421 atagatgatt actttaatgg aaaaagaaaa gtctttaatt taaatattcg tattgaaggg
    15481 actgaatttc aaaaatcagt ttatagggaa atgttaaaaa taccttatgg agaaacattg
    15541 tgttattcag atatagcaag aaatataaac aatccaaaat cagtaagagc aataggacaa
    15601 gcaagtaaaa gtaataaaat tccaataata ataccttgtc atagagtagt tggcaaaaaa
    15661 gatattggtg gatatatggg gaatcattct gatttgaaag agatactatt aaatttagaa
    15721 agacagagtt aacttagaaa gaaatgtttt tattgttaat atttgatata ataatagtaa
    15781 aaagaagtat tttttacaaa aataataagg aatttatttt aatttacaaa aatgaggggg
    15841 gattttaatg tgtgataaag ttatagcatc aaaatatcat gagaagggat ttaattgtgc
    15901 agaatcagtt ataaaagcat ataatgagga atttaataca gatataccag tttgtttagg
    15961 aagtggactg ggttcagggt gtggggttgc tagtttatgt ggtgcagtaa atgcatcaaa
    16021 tataataatt ggatatgtaa aaggcagaaa ccacgaagat gaaagtacta aagctaaagt
    16081 atatgctaaa gatttaacta caacagtaag aaaagagtat ggttcagagt tatgtataga
    16141 cctaaaaaaa gatttagttg cttgtagaga aataatggat tttgcatatg atagtctaaa
    16201 ggaaacttta aaaaaagaat tataagaaaa taagctatca aatataaatt atttgatagc
    16261 ttatttttat agccgatact aaataaatca aatatatttt agaattatta tttgtaaata
    16321 aacagcaaat aattttaggc tttttattta atatagtttt tatttatatt tatttttgaa
    16381 tatgttatac tttgtttaaa taaatatttg taatgaggga gatgagaaga ttgaagaatc
    16441 tcaatttact tattaataaa ttatattcaa aaaatcataa tgaagcatat aaaacttttt
    16501 tattcttaga aaatgaaagt ttaaaatcaa atattacata ttgttttttt gactcattcc
    16561 tagaaatgat tgataacgaa aactcatata ttcgaacaag gggattgtta ttaatctctg
    16621 caaatgctca gtgggatatt gataataaaa ttgaaataaa tatagatagt atactaagtc
    16681 atatcgtaga taaaaaacct tctgtatcaa gaatgtttat taaatccata cctaatatta
    16741 caaagtataa agaaaatctt attaatcgca taaaaatgga attaagtaat gcagatataa
    16801 gtatttataa taataatatg aaaccattag t
//
LOCUS       DAMJXI010000074        16772 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.078, whole genome shotgun sequence.
ACCESSION   DAMJXI010000074 DAMJXI010000000
VERSION     DAMJXI010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16772
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.078"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            227..928
                     /locus_tag="PC465_003099"
     CDS             227..928
                     /locus_tag="PC465_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4253 domain-containing protein"
                     /protein_id="HDF2650382.1"
                     /translation="MSIEDLYDFECVPLNNEIDIDVLFEKMIEDGKEKEYTPIIVIDE
                     KVGLLRKNIDMITKEYGSLENYREYCLTKYNEIDVNQFFDFRKSEISELLKELIDLED
                     DFYDYKHFRPIMNIDIFHEYNKVYIAKIPTIKPYEVFAYIPIGGFNDCPRDEEHIAIA
                     KYWYEKHGIFPIAIGCDTVQYSVKNLTKDGKKFDDLCIELVFYCEDIIIQGYETLKAL
                     KDVLKRSTIVLFWWD"
     gene            1199..2017
                     /gene="larE"
                     /locus_tag="PC465_003100"
     CDS             1199..2017
                     /gene="larE"
                     /locus_tag="PC465_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HDF2650383.1"
                     /translation="MEVNFVKEKEKLDKLKKMLLELGSVVVAYSGGVDSNFLLKVAKD
                     TLGENVIAVTIHAMMHSSREIEEAKQYTQNFGVKHIILNIENFDLKEFKENGVDRCYH
                     CKKYIFSKIKEVAKEHNIKYIVDGTNIDDLGDYRPGLKALSELGVISPLKDSSLKKEE
                     IRSLSKTLGLNTFNKPSFACLASRIPYGVEITDENLRIVEKSEEYLSNLGFSQFRVRM
                     HGDIARIEVGQEELGKFFENNNFNKVDTKLKIFGFKYVTLDMSGYKMGSMNLNV"
     gene            2072..3220
                     /locus_tag="PC465_003101"
     CDS             2072..3220
                     /locus_tag="PC465_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HDF2650384.1"
                     /translation="MKNYTLISPCFFGMEKMLAREITNLGYEIIKTEDGRITYKTDEF
                     GIAKSNMWLRCAERVHLKIAEFEAKSFDELFENTKRINWSRYIPYGAQFPISKASSIK
                     SKLYSTPDVQAIVKKAIVESLKKSYLEDGLLKEDKEKYPIFVFIHKDKVTISIDTTGD
                     ALHKRGYREKANKAPIRETLAAGLIYLTPWKAGRVLVDPMCGSGTILIEAAMIGINMA
                     PGLNREFISEKWRTLDKKIWWDVRKDAFNKIDNESKFKIYGYDIDEESIDIARENAEI
                     AGVDEYIEFNVGDATQFKSEDEFGFIITNPPYGERLEDKDSVKQLYKELGYAFRKLKN
                     WSYYLITSYEDFEYEFGQKADKKRKLYNGMLKTNFFQYPGPKPPRNNK"
     gene            3364..4752
                     /locus_tag="PC465_003102"
     CDS             3364..4752
                     /locus_tag="PC465_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2650385.1"
                     /translation="MKVLKLITVVALMMLFVTGCNIKTESPEQLAKIPDYDDTKKVLY
                     DGIDQLLKPDSSMILPSNTKEVGKINKVDLNSDGIDELVVFEQKEDLSNNVSQVGFVT
                     LSYNGEKYVLGDHFLENGESIEYANFYDLDSDGYKEVILLVKSKDKTNMHIYKVVDNE
                     ITKIYDLDASWLQNKEDFNDMKVKIGYIDGDDKLDILMLHLNNKTNEMFASVANFDGK
                     MKIKDSVKFENVKNLSELYITLGNVASSVGNSSAAIKGIVLDIPILKDNNYITQILYM
                     KDGKINKAFSDYDKTITKSYYIPVDDIDKDKIIEIPIVAGSTGNNKNTYSSKSSATIS
                     WYRWNGKEGADSSLIFTSQIYYNYKYNFKLFIPNNLFDKILVEQEFVGEKAVFKFYYF
                     DYSDRKNLFNIVVESKNKLEDRKNTGTQNSIVLQESDEYTFLLVVNNANEMDKLDMTI
                     DALKEYFSLIYG"
     gene            4781..5479
                     /locus_tag="PC465_003103"
     CDS             4781..5479
                     /locus_tag="PC465_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2650386.1"
                     /translation="MKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTT
                     EKDITIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYI
                     IKPFSIKELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPT
                     EFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYI
                     QTIWGYGYCFRKEE"
     gene            5482..6915
                     /locus_tag="PC465_003104"
     CDS             5482..6915
                     /locus_tag="PC465_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2650387.1"
                     /translation="MLHFEGLRKKVIKNYFIIIIIMVTLFEGLFMFYIQNYYYDSVKQ
                     LLESEIKYADEYNAITMETTSFEKKVKNIFDKQPLTKNSEFGISIIDKDKNIILDQYG
                     FKSKEKANYEDVNNALKDIKTKNLTPYTYRIPDTGEHVMSISLPLKVNNIIEGVVRYT
                     VSLDAIDNAILKQATWLILAGIFILIIAILISLKFAETLIKPLRELKKFANELAVGNY
                     NIKLEKMKIVDDEIGDLAQTFEHMAHEIDKSEKLKEEFISSVSHELRTPLTSIKGWSE
                     TLGYESITREELDLGLGIIQDETERLIKLVEELLDFSRLSSDRIKLHVDIVDVEGLIV
                     GVVNQLKVKAAEKDISLLFEFENEFIENIQGDKNRLRQVLINLIQNSFKFTSQGGYIK
                     VVASQDEEITTISVEDNGSGIEKQNLNKVLDKFFQEDYNKAGSGLGLAISNEIVKLHG
                     GRMKIESEKNVGTKITFNIKNKFAKQA"
     gene            6937..7674
                     /gene="truA"
                     /locus_tag="PC465_003105"
     CDS             6937..7674
                     /gene="truA"
                     /locus_tag="PC465_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDF2650388.1"
                     /translation="MRNIKMIVAYDGSRYKGYQKLGDNNMTIQEKLENVLSKMTNETV
                     EIIGSGRTDMGAHARGQVVNFRTNCMDSLDKIQKYLYEYLPEDIVVKTVEEVDERFHS
                     RYNVKSKTYMYKIDNNKYHNPFIRKYATHVSKKLDLDRMRKASEYLVGEHDFTSFASS
                     KSKKKSNVREIYSINIKEDDNVIEIYVEGNGFLYNMVRIIVGALIDVGLKRRAPQDIK
                     YMLESKDRCQSSDTAPAKGLCLWKVTY"
     misc_binding    7785..7992
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8245..9444
                     /locus_tag="PC465_003106"
     CDS             8245..9444
                     /locus_tag="PC465_003106"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HDF2650389.1"
                     /translation="MKEKVVLAYSGGLDTSIIIPWLKENYEDIDVIAVCGNVGQEDKM
                     EDVYEKALQSGASKAYVDDISEEFVTETIFKAVKAEAKYEGKYLLGTSLARPIIAKKL
                     VEVAHKEGAKYICHGCTGKGNDQVRFEATIAALDPTIKVIAPWRIWNIKSREDAIDYA
                     EKHNIKVTATKAKIYSVDANLWHVSTEGGDIEHLENEHKKDVYKQCVDPEDACDVAEY
                     VEVYFEKGVPKKVNGEELSPVALIHKLNELGCKHGIGVIDIVENRLVGMKSRGIYETP
                     GGTILYEAHNILESATLDKDTLHFKQMVSYKYGELIYNGLWYCKLRESIDAFMEQTQD
                     NVTGTVKVKLYKGNIKPAGIFTENALYDEGISSFGNSELYDHKDAEGFINLFTLPLKI
                     RAMKAGK"
     gene            9691..10737
                     /locus_tag="PC465_003107"
                     /pseudo
     CDS             9691..10737
                     /locus_tag="PC465_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889743.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4872 domain-containing protein"
     gene            10845..12008
                     /locus_tag="PC465_003108"
     CDS             10845..12008
                     /locus_tag="PC465_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2650390.1"
                     /translation="MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDES
                     IKTLQQILFFKEIDIPLREVKEIMSSQYFDKVEALKNQKKLLILKRKRLDELIELINQ
                     TLRGEGNIDFKEFDMSEYFDVLEEFKREHRNKVIKIYGSVEKYNEYIERVKSNEEKIA
                     KMAIKQYGTIEKFAQAIKTNFSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDL
                     SRNHSSTDLQEIAKEITDISKKDYEIFSMDTGDDNWYYMVQNYLVNPMWIEEVDKKYG
                     SGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSREVQSIVEEIDNEMKRSNE
                     FYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGDGASKFIGEAFKIYFDNNNC"
     gene            complement(12097..12477)
                     /locus_tag="PC465_003109"
     CDS             complement(12097..12477)
                     /locus_tag="PC465_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4363 family protein"
                     /protein_id="HDF2650391.1"
                     /translation="MKSTTFVILWTILFVLFGFYVNNKLYDFTEGYKDNISVLEKSIE
                     NEDWEKAQKEADSISTSWNKEKNHWYKVLNHEYFDEIGLRFNILDKAIYTENKLKSLE
                     EVESIKTYLGNIIESVKFDVNYIF"
     gene            complement(12480..13139)
                     /locus_tag="PC465_003110"
     CDS             complement(12480..13139)
                     /locus_tag="PC465_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HDF2650392.1"
                     /translation="MTVVLIRSIILYITVLIALRVMGKGEIAEMNCFDLVITLLIAEV
                     ASVPMENNNIPIINGVAAISGLVIMQTLISFLSLKSRKLSSFLSGKPSVLIDKGKIVY
                     KELKKERISIDELLEQLRIQGYFNLKDVQYAILETDGNLSVVPASSYNSTPPRAFNHL
                     PIPLILDGRIINKNLDIAQKDTNWLMGILKSNHIETFKDVLICVLDENDKIFIQNKKG
                     D"
     gene            complement(13245..14219)
                     /locus_tag="PC465_003111"
     CDS             complement(13245..14219)
                     /locus_tag="PC465_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HDF2650393.1"
                     /translation="MKYKLFIDFEFNILDDNKNKPKEYNGAELISIGGVLVDNEFNTI
                     DNYYSLVKPKYNKILSNKCKNLTKLNQLDINNAPNLLYVMDDFYKWFCKFDDVTIYNW
                     GDFDITGLLTSFRVYKYTGKCLELFNMMIDIQPFISQHITYNNRILSKQISLLNMKKI
                     FSVEGDIKHNSLSDAVDLMNVCKCFFFNSPKNIDILEELYNKLPALKTPLYYIPYFED
                     ENFELKFDRTPEDIIIYLKQILTILNISKKEIYFKKRSVLVNNSKIINFKNLSSSFKL
                     IKLNEFEEYPDFILKLGDKKSFVESVIKINKSNRKSIKNLILKLSKKP"
     gene            complement(14259..14606)
                     /locus_tag="PC465_003112"
     CDS             complement(14259..14606)
                     /locus_tag="PC465_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650394.1"
                     /translation="MLNLKEIREEIIKKYIGDSLISELTEELKNILITDLQSNPFKSN
                     IELSIIPANIEIFKKIENILIDSKVNLKMGWERILINYILKDLFELNYEINKSCNEPL
                     MFRVIISIDSYDA"
     gene            complement(14824..15789)
                     /locus_tag="PC465_003113"
     CDS             complement(14824..15789)
                     /locus_tag="PC465_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HDF2650395.1"
                     /translation="MKKILITGALGQIGSELTIKLRNEYGEQNVIASSRRVKEGNPVC
                     ESGIFGIFEILDVTDKNRFFEIAKKYDVDTIIHLASLLSAVAESKPLEAWNLNMNGLI
                     NGLEIAKELDCKFFTPSSIAAFGENSPKNMTPQDTLQRPNTMYGVTKVSGELLCDYYH
                     SKFGVDTRGVRFPGLISYVTPPGGGTTDYAVDIYYEALKNKRYKSYIAEGTKMDMMYM
                     PDALQSIVDLIEAPADKLIHRNAFNITAMSFSPEEIADSIKKYIPDFVIEYDVDPVRQ
                     SIADSWPNSLDSSSAVKEWNFKFSYDLDKMTKDMLEKLSEKGIGK"
     gene            16232..16600
                     /locus_tag="PC465_003114"
     CDS             16232..16600
                     /locus_tag="PC465_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HDF2650396.1"
                     /translation="MTRPSIYHSQGYTCAEALIKSYNEEHNTDIPISIGSGMGVGMNV
                     GSVCGAVNAAVVIIGYLNGRNSNLDENIARKYSRELLNRVRNKYSSEICVSLKKNKVT
                     CEEIINFTYDALNDMLKNQK"
BASE COUNT         6609 a         1766 c         2717 g         5680 t
ORIGIN      
        1 accatgaaca tttgttttgt gctatcatat ttatataagg taattatcat aaaaaatatc
       61 ttgttcatac agttttatat agaaaaaaga aatgaagctt ttctttatat aagtatattt
      121 tgtaaattgc ctctatattt atagtttaaa taatagtggt attaaaaatc tgacaacaaa
      181 aataaaactt tcaaaaaatt aaatctaaaa agaataggag ataaatatga gtattgaaga
      241 tttatatgat tttgaatgtg ttcctttgaa caatgagatt gatattgatg ttttatttga
      301 aaagatgata gaagatggaa aagaaaaaga atatacacca attatagtca ttgatgaaaa
      361 agtagggcta ttaagaaaaa atatagatat gattactaaa gagtatggtt ctcttgaaaa
      421 ctatagagag tattgtttaa caaaatataa tgaaattgat gtaaatcaat tttttgattt
      481 taggaagagt gagatttcag aattattaaa ggagctaatt gatttagaag atgattttta
      541 tgattataaa cattttagac caattatgaa tatagatata tttcatgaat ataacaaagt
      601 ttacatagct aaaattccaa caattaaacc atatgaagta tttgcataca tacctattgg
      661 cggatttaat gattgtccta gagatgaaga acatatagct attgcaaaat attggtatga
      721 aaagcatgga atctttccaa tcgcaattgg atgtgataca gttcaatatt ctgtaaaaaa
      781 tttaactaaa gatggtaaaa aatttgatga cttatgtatt gaattagtat tttattgtga
      841 ggatattatt atacaagggt atgaaacctt aaaggctctt aaggatgtat taaaacgctc
      901 tacaatagtg cttttttggt gggattgata ttctatcatt tagatagtat taaattgtta
      961 gtcaccaaga atccacttgc tttagttatg gggagtgtgt caaactaggt ttttatacac
     1021 agtgtagcat agtaatatgt ttaaattaca aaggttaaaa aaatacttta atatttttaa
     1081 tattataatt aatagattta aaggtaatta taatttataa aataaatact ttatatgtta
     1141 taatcattaa gaatgtaaaa aaataatata tagttttata gttcatattt ttccagatat
     1201 ggaggtaaat tttgtgaagg aaaaagaaaa attagataaa ttaaaaaaaa tgttacttga
     1261 attaggcagt gttgtagttg cttattctgg tggagtagat agtaattttt tgcttaaggt
     1321 tgcaaaagat acattaggtg aaaatgttat agctgtgact attcatgcaa tgatgcattc
     1381 aagtagggaa attgaagagg ctaaacaata tactcaaaat tttggtgtta aacatatcat
     1441 attaaatata gaaaactttg atttaaaaga atttaaagaa aatggtgttg atagatgtta
     1501 tcattgtaaa aaatatatat tctctaaaat aaaagaggta gcaaaagaac ataatataaa
     1561 gtacatagta gatggaacaa atatagatga tttaggagac tatagacctg ggcttaaggc
     1621 attgagtgaa ttaggagtaa ttagtccatt aaaagatagt agtttaaaaa aagaagaaat
     1681 taggtcgctt tcaaaaacat taggattaaa tacttttaat aaaccatcat ttgcatgtct
     1741 tgcgagtagg ataccttatg gagttgaaat aacagatgaa aatttaagaa tagtagaaaa
     1801 gagtgaagaa tatctatcca atttaggttt ttctcaattt agagtgagaa tgcatggaga
     1861 tatagctaga atagaagttg gacaggaaga actaggtaaa ttttttgaaa ataacaattt
     1921 taataaagtt gatactaaat taaaaatatt tggctttaaa tatgttacac tagatatgtc
     1981 aggatataaa atgggaagta tgaatttaaa tgtgtagatt attttaaaaa taaataagtt
     2041 ttatagttaa tataaggaaa caggaggttt tatgaaaaat tatacgttaa tatcgccatg
     2101 tttttttgga atggaaaaaa tgctggctag agagattact aatttaggat atgaaataat
     2161 aaaaacagaa gatggaagaa taacatataa aactgatgag tttggaatag caaagtcaaa
     2221 catgtggttg agatgtgctg aaagagtaca tcttaaaatt gctgaatttg aggcaaaaag
     2281 ctttgatgaa ttatttgaaa atacaaaaag aataaactgg tctagatata taccttatgg
     2341 agctcaattt cctatatcaa aagcttcctc tataaaatca aaattataca gtacaccaga
     2401 tgtacaagcc atagtaaaaa aggctatagt agaaagctta aagaaaagtt atttggagga
     2461 tggtttgctt aaagaagata aggagaaata ccctattttt gtatttatac acaaagacaa
     2521 agtaaccatt tctatagata caacaggaga tgctttgcat aagagaggat atagagaaaa
     2581 ggcaaataaa gctccaataa gagagacttt agctgctggg cttatttatt taactccctg
     2641 gaaagcaggt agagttttag tagaccctat gtgtggttct ggtactatat tgattgaagc
     2701 tgctatgatt ggtataaata tggcacctgg cttaaataga gagtttatat cagaaaagtg
     2761 gagaactctt gataagaaaa tatggtggga tgtaagaaaa gatgctttta ataagataga
     2821 taatgaatct aaatttaaga tttatggata tgatatagat gaagaatcta tagatatagc
     2881 tagagaaaat gctgaaatag caggtgtaga tgaatatata gagtttaatg taggagatgc
     2941 aactcaattt aaaagtgaag atgagtttgg atttataatc actaatcctc cttacggaga
     3001 aagattagaa gataaagaca gtgttaaaca gttgtataag gagcttggtt atgcatttag
     3061 aaaattaaaa aattggtcgt attatttgat aacttcttat gaagactttg aatatgagtt
     3121 tgggcaaaaa gcagataaaa aaagaaaatt gtataatggt atgttaaaaa ctaacttttt
     3181 ccaatatccg ggtcctaagc ctcctagaaa taataaataa gttttacatg atttatttgt
     3241 aaaatataaa attttattaa aataagtaaa acattatgat gccttgaaac gtctaattat
     3301 tgtgaggaga tttttgtgaa caaatttaaa gatttaaaga tttataggat taggaggagt
     3361 taaatgaaag tgttaaagct tattactgta gtagccctga tgatgttatt tgttactgga
     3421 tgtaatataa aaactgaatc tccagaacaa ttagcgaaga tacctgacta tgatgataca
     3481 aaaaaagtat tgtatgatgg tattgaccag ttactaaaac cagattcatc tatgatattg
     3541 ccttctaata caaaagaagt aggaaaaata aataaggtag atttaaacag cgatggaatt
     3601 gatgaattag tagtatttga acaaaaagaa gatttaagta ataatgtgag tcaggtaggg
     3661 tttgtaacct tgagttacaa tggagaaaaa tacgtacttg gagaccattt tttagaaaat
     3721 ggcgaatcaa tagaatatgc taatttttat gatttggact cagatggata taaggaagtt
     3781 atcttattgg ttaaatccaa agacaaaacg aatatgcata tatataaagt agtagataat
     3841 gaaataacaa aaatatatga cttggatgca tcatggcttc aaaataaaga agattttaat
     3901 gacatgaaag taaaaattgg atatatagat ggagatgaca agttagacat attgatgctt
     3961 catttgaata ataagactaa tgaaatgttt gcaagtgttg caaattttga tgggaaaatg
     4021 aaaatcaaag attctgttaa gtttgaaaat gtaaaaaact taagtgaatt atatataaca
     4081 ttaggtaatg ttgcttcatc tgttggaaat tcttctgcag ctataaaagg tattgtactt
     4141 gatattccta tattgaaaga taataactat attacgcaga tactttatat gaaagatggg
     4201 aaaattaaca aagcttttag tgattatgat aaaactatta ctaaatctta ttatatacct
     4261 gtagatgata ttgacaaaga taagattata gaaataccta tagttgcagg cagtacaggt
     4321 aataataaaa atacttatag ttctaaatca tctgcaacta taagttggta tagatggaat
     4381 ggaaaagaag gtgctgactc aagtttaata tttacaagtc agatatatta taattataaa
     4441 tataatttta aattatttat tccaaataat ttatttgata aaatacttgt tgaacaggaa
     4501 tttgttggag aaaaagcagt atttaaattt tactattttg actattcaga ccgtaagaat
     4561 ttatttaata tagtagtaga gagtaaaaat aaacttgaag atagaaaaaa tacaggtact
     4621 caaaattcta ttgtacttca agagagcgat gaatatactt tcttactagt tgtaaacaat
     4681 gcaaatgaaa tggataagct agatatgact atagacgcat taaaagaata tttctcatta
     4741 atatatggtt aatattatac tcaattggag gttttatttt atgaaggaaa agatacttat
     4801 actagaagat gaaattggta ttagaagttt tgttagtata aacttaaaaa gggaaggcta
     4861 tgaaatagtt gaggcaggta ctggaagaga agctatagaa aaaatgacaa cagaaaagga
     4921 tattacaata gctcttttag atgtaatgct tccagatata agtggtatag aagtatgtaa
     4981 atttataagg gagaattttg accaagtagg tataataatg cttactgcta aagctcaaga
     5041 agatgataaa atagaaggat ttatctcagg agcagatgat tacatcataa aaccatttag
     5101 tataaaagag cttttagtca gagtttctgc tcttcttaga agagtagcaa aggatgattc
     5161 aagtgttaag tcgagtgaga tagtttctcc accatttata cttgatatag acaaaagaaa
     5221 attatttaaa aatggaaagg aaattgagct tacaccaact gaattttcaa tagtgaaata
     5281 tctaatatca aatgctaagc agtcgttaag tagagaccag atattagacg aagtatgggg
     5341 aactaactat ttatatgatt ttaaaatagt agatgtaaat ataagaagga taagaaataa
     5401 aatagaagat gacccatcaa aaccaaaata tatacaaact atttggggtt atggatactg
     5461 ttttagaaag gaagaataat agtgttacat tttgaaggtc tgagaaaaaa agtaataaaa
     5521 aactatttta taataattat tataatggtt actctgtttg aaggattgtt catgttttac
     5581 atacaaaact actattatga ttctgtcaaa cagctacttg aatctgaaat aaaatatgct
     5641 gatgaatata atgctattac aatggaaact acaagttttg agaaaaaagt aaaaaatata
     5701 tttgataaac aacccttaac taaaaattca gaatttggaa tttcaataat agataaagat
     5761 aaaaatatta tattagacca atatggtttt aaaagtaaag aaaaagcaaa ctatgaagat
     5821 gttaacaatg cattaaaaga tataaaaact aaaaatttaa caccttatac ttatagaata
     5881 ccagatacag gagagcatgt tatgagtatc tccttaccac ttaaggtaaa taatataata
     5941 gaaggtgttg ttagatatac agtatcatta gatgctattg ataatgcaat attaaagcaa
     6001 gctacatggc ttatattagc aggaatattt atacttatta tagctatact aataagtctt
     6061 aaatttgctg agactcttat aaaaccatta cgagagctaa agaaatttgc aaatgaattg
     6121 gctgtaggaa attataatat aaaattagaa aagatgaaga ttgtagatga tgaaattggt
     6181 gatttagcac agacatttga acacatggca catgagattg acaaaagtga aaaattaaaa
     6241 gaggaattta tatcatctgt atctcatgaa ctaaggactc ctcttacatc tataaagggg
     6301 tggagtgaaa ccttaggtta tgaaagtata acaagagaag aactagactt aggtttaggc
     6361 attatacaag atgaaacaga aagacttata aaactagttg aagaattatt agacttttca
     6421 aggctttctt cagacaggat aaaacttcat gttgatatag ttgatgttga aggtttaatt
     6481 gtaggtgttg taaatcaact taaagttaaa gcagctgaaa aagatatatc acttttattt
     6541 gaatttgaaa atgaatttat agagaacatt caaggagata aaaatagatt aagacaggtt
     6601 ctcataaatt taatacaaaa ttcatttaaa tttacgagtc aaggtggtta cataaaagtt
     6661 gtagcttctc aagatgaaga gataacaacc atatcagtag aggataatgg ttcaggtata
     6721 gaaaagcaaa atttaaataa agtgttagat aaatttttcc aagaagatta taataaggct
     6781 ggtagtggat taggactagc aattagtaat gaaattgtaa aacttcatgg tggaagaatg
     6841 aaaatagaaa gtgaaaagaa tgttggaaca aaaataactt ttaatataaa aaataaattt
     6901 gctaaacaag cataaattct tagaaagagg attaagatga gaaacataaa aatgatagta
     6961 gcatacgatg gttcaagata taaaggatat caaaaattag gtgacaataa tatgactatt
     7021 caagaaaaac ttgaaaatgt tttaagtaaa atgactaatg aaacagtgga gataataggt
     7081 tctggaagaa ctgatatggg agctcatgca agaggacaag tggtaaattt tagaactaat
     7141 tgtatggatt ctttggataa aattcaaaaa tatttatatg aatatttacc agaagatata
     7201 gttgtaaaaa ctgttgaaga agttgatgaa agatttcatt caagatacaa tgtaaagtca
     7261 aagacttata tgtataaaat tgacaataat aagtatcata atccttttat aagaaaatat
     7321 gctactcatg taagtaaaaa attagattta gatagaatga gaaaagcaag tgagtattta
     7381 gtaggagaac atgattttac tagttttgct tcttctaaat ctaagaaaaa atcaaatgta
     7441 agagaaattt attctataaa tataaaagaa gatgataatg ttatagaaat atatgtagaa
     7501 ggaaatggat ttttgtataa catggtaagg ataatagtag gtgctttgat agatgttggt
     7561 ctaaaaagaa gagctccaca agatattaag tatatgcttg aatcaaaaga tagatgtcaa
     7621 tcatcagata ctgcaccagc taaaggacta tgtctttgga aagtaacata ttaatcaatt
     7681 atataaaact ctctttaaaa taaaaataaa ataaattata tagttgacat aaatggaaaa
     7741 ataaactatt atatatttta taagagagat ataaaacttt atatttaaat cctgtgagaa
     7801 agagagtaac ttctatgtgt tttatagaga gctgaggatg gtggaagctt ggcaaataag
     7861 tattagtgaa aagaactttg gaggatacta attgaattta gtatgttagt aggtaatctc
     7921 gccttaagag aaagagtgga taagtttatc ttatcaatta gagtggtaac gcggatatat
     7981 ttcgtctctt ggtttttcca agaggcgttt tttaatatat ttaattatta gtgtttatct
     8041 ggtatgttga acatttacta attgattagc taagtttatc aataagagtg gtaccgcgga
     8101 tatttcgcct cttagtattt taaaatacta aggggttttt ttagtattaa aatgatttta
     8161 tgtgagtcta aattctcaga gtcattcaat attaagaatt tctataaaat aaaaattata
     8221 atttaagatt gggaggaatt aaaaatgaag gaaaaagtag tattagcata ttcaggagga
     8281 cttgacacat caatcataat accttggtta aaggaaaatt atgaagatat agatgttata
     8341 gctgtttgtg gaaatgtagg tcaggaagat aaaatggaag atgtatatga aaaagcttta
     8401 caaagtggag catcaaaggc atatgtggat gatataagtg aagaatttgt aactgaaact
     8461 atatttaaag ccgtaaaagc agaggctaaa tatgaaggaa aatacttatt aggaacttct
     8521 ttagcaagac ctataatagc taaaaaatta gttgaagttg ctcataaaga aggtgcaaaa
     8581 tatatatgcc atggatgtac aggaaaaggt aatgaccaag ttagatttga agctacaatt
     8641 gcagctcttg acccgactat aaaagttatt gcaccttgga gaatttggaa tataaaatca
     8701 agagaagatg ctatagacta tgctgaaaaa cataatataa aggtaacagc aactaaagct
     8761 aaaatatatt cagtagatgc taacctttgg catgtttcaa cagaaggtgg agatatagag
     8821 cacctagaaa atgaacataa aaaagatgtt tataaacaat gtgtagaccc agaagatgca
     8881 tgtgatgtag ctgaatatgt agaagtttac tttgaaaaag gtgtacctaa aaaggtaaat
     8941 ggcgaagaat tatctccagt tgcactgatt cataagttaa atgagttggg ttgtaaacat
     9001 ggaattggtg ttatagatat agttgagaat agacttgttg gtatgaaatc aagaggtata
     9061 tatgagactc caggaggaac aatcctttat gaagcacata atattttaga aagtgctact
     9121 ttagacaaag atacattaca tttcaaacaa atggtatctt ataaatacgg agaacttatt
     9181 tacaatggac tatggtattg taaattaaga gaatctatag atgcatttat ggaacaaact
     9241 caagataatg ttacaggaac agtaaaagtt aaactttaca aaggaaatat aaaacctgct
     9301 ggaatattta ctgaaaatgc tctttatgat gaaggaatat cttcttttgg aaatagtgaa
     9361 ctttatgacc acaaagatgc agaaggattt attaatttat tcactttacc attaaaaatc
     9421 agagctatga aagctggaaa ataataaaat aaattattta agagtgtata aaaactattt
     9481 ttaggttttt atatgctctt tttttatttg aatttattaa attatacagt aaatagtata
     9541 aaaaaatata ttatagttcc aaatggctta ataatgtgaa aatataagac ctaaaatata
     9601 aattttataa atacaatagt tattgactct ctcattgtaa gagggtttat actgaatcta
     9661 atgaaaattt atagtgagga gatagattat atgagaaaaa taattgaaat taaacatcat
     9721 tcacatgatt atgagtgtat gtggaatggt atagaagatt tatatataaa taaaaccggt
     9781 gaatgccttc caaacgattt tttcttttta ctgtcaggtt ttggttcatt ttgttatatg
     9841 aaaacaaata aagctgattt gaaaagaatg gtagctttgg gagatggaag gacaaaacag
     9901 atgtataaat ttttagcacc aattgttgga tttgaataca aacatcatga gtttaaaaag
     9961 tatgagcaag cattaaagaa agcaaaatct gaaattgatg atggatatcc agttatttta
    10021 ggagctttag atatgtatta tctaccatat tataagaagc tatatcataa agaacacatt
    10081 ccttttcatt atatattaat ggtaggatat gatgatgaag gaatatatct gtatgattgt
    10141 ggtagaacag aattattaca tctttcttat gataaattac gtgaaagcat gaattgaaat
    10201 tcccctggat taagcaaaga aaatactatt tgcacaataa gaatgaatac ttcaaagaat
    10261 aaatataaca ttgctagaga agctattgct ataaagcgtg atatgttttt aaatccacct
    10321 aaaggatttt tgggatataa aggttttgaa aagtttatta aagagttgcc acagtggaac
    10381 actgaattgg ataaagatga ttatgataag attttgacca atatggttat gttttttgga
    10441 acagtaccaa caattccaaa tgcaatcaaa ggaattaaag aaccagatac tgttcaattt
    10501 aaaggtggat ttgataaaat gagtagaatg ctcaacagta ttggggagga atacaaaaac
    10561 gactctttta tacaagtagc tgatattttt gataaaactg ctattataat tgagaaaata
    10621 tccaatatta taatagatta cttaactcaa acatgtgatg atacaggaca acttccgtta
    10681 ttgttctctg aggtcttaga gcatatgaaa acaggatatt taatcttgga tgtataaaaa
    10741 atatattgtt gaccctaaca ttacgtaata gtgtaatatg aaaatatagc ttgaatatat
    10801 tagtaggtat tgatggctgt aaaattaaaa tttgaggtgt ggatatgaga acagtgaaac
    10861 aagtttctga tttaactgga ataagtgtga gggcattaca ttattatgat gaaataggtc
    10921 ttttaaaacc aaataaaatt acagatgcag gatatagact ttatgatgat gaatctatta
    10981 aaactcttca acaaatttta ttttttaagg agattgatat tcctttaaga gaggttaagg
    11041 aaataatgtc aagccaatat tttgataagg ttgaagctct aaaaaatcaa aaaaaattac
    11101 ttattttaaa acgaaagaga ctggatgaat tgatagagct tataaatcaa actctaagag
    11161 gagaaggaaa tattgatttt aaagagtttg atatgagcga gtattttgat gttttagaag
    11221 aatttaaaag agagcatagg aataaggtaa ttaaaattta tggtagtgta gaaaaataca
    11281 atgaatatat agaaagagtt aagtctaatg aagagaaaat tgctaaaatg gctataaaac
    11341 aatatggaac tattgagaag tttgcccaag ctataaaaac aaattttagc agtgatatat
    11401 tgaatttagg agaaaaattt gatagatata aaaatgattg tttaaaagaa aaacatccaa
    11461 aattaaaaga attatataga aagcttgtag aagatttaag taggaatcat tcttcaacag
    11521 accttcaaga aatagcaaaa gagataacag atatatctaa aaaagattat gaaattttct
    11581 ctatggatac tggtgatgac aactggtatt atatggttca aaattatcta gtaaatccta
    11641 tgtggataga agaagtagat aaaaagtatg gaagtggagc aggtaagttt attggacaag
    11701 tactaaagac ttatctaaga gatagaaaac caaagataaa tacattgtat gaaaaacttg
    11761 tagaagattt gagtagagat tgttcttcaa gggaagttca aagcattgtt gaagaaatag
    11821 acaatgaaat gaaaagaagt aatgaatttt ataaaataga caatggtgaa agatactttg
    11881 attatatgtc agagctttat ttacaagatt ctaactatat aaaagtaact gataagaatt
    11941 atggtgatgg tgcatctaag tttattggag aagcttttaa gatttatttt gataataata
    12001 attgttgaaa atttggaagt aaaaaatatg taagttttat aaaagcacaa aaataaggat
    12061 gtagattagc tccatctata tccttattta aagttattaa aatatatagt ttacatcaaa
    12121 cttaacactt tcaataatat ttcccaaata tgtttttata ctttcaactt cttctaaaga
    12181 ttttaattta ttttcagtat aaattgcttt gtccagaata ttaaacctta atcctatttc
    12241 atcaaagtac tcatgattta aaactttgta ccaatggttt ttttctttat tccaactcgt
    12301 agatattgaa tcagcttctt tttgagcttt ttcccaatct tcattttcta tagatttttc
    12361 taaaacagat atattgtctt tatatccttc tgtaaaatca tatagtttat tgttaacgta
    12421 aaatccaaat aatacaaata agatagtcca tagtataaca aatgttgtag atttcaatat
    12481 taatcaccct ttttattttg aataaatatt ttgtcatttt catctaaaac acaaataaga
    12541 acatctttaa aagtttctat gtgattagat tttaaaatac ccattaacca gttagtatct
    12601 ttttgagcta tgtctagatt tttatttatt attctaccat ccagtataag tgggataggt
    12661 aaatgattaa aagctcttgg aggagtacta ttgtagcttg atgctggtac aacacttaga
    12721 ttaccatcag tctccaaaat agcatattgt acatctttta ggttaaagta tccttgaatc
    12781 ctaagttgtt ctaataattc atctatacta attctttctt ttttaagctc tttatataca
    12841 atttttcctt tatctattaa tacagaaggt ttacctgata aaaatgaact taattttctg
    12901 ctttttaatg ataagaatga aattagagtc tgcatgatta caagtccaga tattgctgca
    12961 acaccattta tgattggtat attattattt tccattggga cagatgcaac ttctgcaatt
    13021 aatagtgtta taactaaatc aaaacagttc atttcagcta tttcaccttt tcccatgact
    13081 ctaagtgcaa ttagcactgt tatgtataat ataatacttc ttattaatac tactgtcata
    13141 tctatcaatt actcctttaa aaaatattta cacttagtta gtatatccta tataaaaaat
    13201 ttaattcaaa gtataaaaaa ccttaaataa ttggattcaa ctatttaagg tttttttgat
    13261 aattttaata ttaaattttt tatggatttt ctgttacttt tatttatttt aataacagat
    13321 tcaacaaaac tctttttatc tcctaatttt aagataaaat caggatattc ttcaaattca
    13381 ttgagtttta ttaatttgaa agaagaagat agatttttaa agttaataat tttagagtta
    13441 ttcactaata cacttctttt tttaaaataa atttcttttt tacttatatt tagtatagtt
    13501 aatatttgtt taagatatat tattatatct tctggagttc tatcaaattt gagttcaaaa
    13561 ttttcatctt caaagtaggg aatataatat aaaggtgttt tgagagcagg taatttatta
    13621 tataattctt caagaatatc gatattttta ggggagttaa agaaaaagca tttacacaca
    13681 ttcattaaat ccacagcatc tgaaagtgag ttatgtttaa tatctccttc tacagaaaaa
    13741 atttttttca tattcagtaa agatatttgc ttagataaga ttctattatt gtatgtaata
    13801 tgttgagata taaaaggttg aatgtcaatc atcatattaa ataactctaa gcatttacct
    13861 gtatatttat atactctaaa tgaagttaga aggccagtta tatcaaaatc accccaatta
    13921 tatattgtaa catcatcaaa tttacaaaac catttataaa aatcatccat aacatataaa
    13981 agattaggag cattattgat atctagttgg ttcaatttgg ttaaattttt acatttattt
    14041 gaaagtattt tattgtattt tggcttaact aaagagtaat aattatctat tgtattaaat
    14101 tcgttatcaa ctaaaactcc accaatagaa attaattccg caccattata ttcttttggt
    14161 ttatttttat tatcatctag tatattaaat tcaaagtcta taaataactt gtatttcata
    14221 aatctaaagc acatcctcag gtaaattatt tattgagcct aagcatcata agaatcaata
    14281 gatataatga ctctaaacat caaaggttca ttacaacttt tatttatttc ataatttaat
    14341 tcaaataaat cttttaagat ataatttata agtattcttt cccaacccat ttttaaatta
    14401 actttagagt ctattaatat attttctatc tttttaaata tttctatatt tgctggtatt
    14461 atactgagct caatattact tttaaacggg ttagactgta aatctgttat aagtatattt
    14521 tttaattcct ctgtaagttc agaaattaaa ctatcaccta tgtatttttt tatgatttcc
    14581 tctctaattt cttttaaatt tagcaatatt agtacctgct acttacatag tagcttttcc
    14641 tttcctttta atactattat tcatttttga atcttattta gatatatttt aagattaaaa
    14701 gtctttagct atataatttt ttacccattt ttaacttata ttaacatatt acaggcttat
    14761 atctccaccc tgcttacatt gaggatggag tatattgcct attttgataa aaatgatagg
    14821 ttgttatttg cctattcctt tttctgataa tttttctaac atatctttgg tcattttatc
    14881 taaatcataa ctaaacttaa agttccattc ttttactgca ctactactgt ctagagagtt
    14941 aggccaagaa tcagctatac tttgtcttac agggtctaca tcatattcta tcacaaaatc
    15001 aggaatatat ttttttatag aatcagctat ttcttcagga gaaaagctca tagcagtaat
    15061 attaaaagca tttctatgga tgagtttatc agctggagct tcgattaaat ccactattga
    15121 ttgaagtgca tcaggcatat acatcatatc catttttgta ccttctgcta tataagattt
    15181 atatctctta ttttttaatg cctcataata tatatcaact gcataatctg tagttcctcc
    15241 accaggaggc gtaacataag aaataagacc tggaaatcta acacctctag tgtctactcc
    15301 aaattttgag tgataataat cacatagtaa ttctccagaa actttagtca caccatacat
    15361 agtattaggt ctttgtaatg tatcttgagg agtcatattt tttggagaat tttcaccaaa
    15421 agcagcaatt gaactaggtg taaaaaattt acaatccaat tctttggcta tttcaagacc
    15481 atttattaat ccattcatat ttaagttcca agcttctaga ggtttacttt cagcaactgc
    15541 agaaagtaaa gatgctagat gaattatagt atctacatca tatttttttg caatttcaaa
    15601 aaaacgattc ttatctgtaa catctaatat ctcaaatata ccaaatatac cagattcaca
    15661 tactggatta ccttctttta ctctccttga actagcgatt acattttgtt ctccatactc
    15721 atttctaagc tttattgtta attctgaacc tatttgtcct aatgcacctg ttataagtat
    15781 ttttttcaat ttcacaacct cctaagggtt taatttatgt agtactactt atttttattt
    15841 tagcaaatct tttgtttaaa tacaaagaat taaagataat aatatacgac ttaattgaat
    15901 gaagtgcagt aagtgcctaa aaatttaaag ctaatatata atggtctatt gtataacaat
    15961 aaaagagtag attaaattat tatatataga ttgtgtgact aagtcacaga aaatagagtt
    16021 aatttaatat ataataaaag catatcaagt aaagctttaa attaaagtaa ctttatataa
    16081 aaagtaatat aaattgataa aattataaat ttatttatag tgaatatagg ttggatttta
    16141 tagatacaaa aatagtatat atgatatgta gaccattagc atgtttaaag tagcaaaaca
    16201 tataaaataa aatttgaaag gaagtataaa aatgacaaga ccatcaatat atcatagcca
    16261 aggatacact tgtgcagagg cattaataaa gtcttataat gaggaacaca acacagatat
    16321 accaatctca ataggaagtg gtatgggggt tggaatgaat gttggaagtg tttgtggagc
    16381 tgtaaatgct gctgttgtta taatagggta tttaaatggg cgaaatagta atttagatga
    16441 aaatatagca aggaagtatt caagagagct attgaataga gtaagaaata aatacagctc
    16501 agaaatatgt gtatctctta aaaaaaataa agtaacttgt gaagaaataa taaatttcac
    16561 atatgatgct ctaaatgata tgctaaaaaa tcaaaaataa ttctaagaaa caagtatttt
    16621 acattcgata gaatacttgt ttttttatga tatttttaat aagtattagt ttattataat
    16681 ttttaaatca attttattat attttaattg aaacaatcta ctttgaaaat tactaactga
    16741 caaaagaata tgattatagt atagaaaaaa tg
//
LOCUS       DAMJXI010000075        16757 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.079, whole genome shotgun sequence.
ACCESSION   DAMJXI010000075 DAMJXI010000000
VERSION     DAMJXI010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16757
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.079"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(100..615)
                     /locus_tag="PC465_003115"
     CDS             complement(100..615)
                     /locus_tag="PC465_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HDF2650397.1"
                     /translation="MDFLAKYKVLKKQNSSKSCLVCGTQNELGLKADFYELENGELVS
                     ICNTKDWHQSYPGRVHGGMSAAILDETIGRAVSINDDQIWGVTVSLELKYKKPVPTDA
                     TIKVVGRITKENRKLFEGTGEIILPNGDIAVTATGKYMKMPIGQIAEGDFSNEEWFFE
                     ESKEKVEYIEL"
     gene            complement(978..2048)
                     /gene="leuB"
                     /locus_tag="PC465_003116"
     CDS             complement(978..2048)
                     /gene="leuB"
                     /locus_tag="PC465_003116"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HDF2650398.1"
                     /translation="MNCNIAVIKGDGVGPEIIDEGIKVLNKICCKFNHRFDCEYVLAG
                     GCAIDETGEPLPNKTVETCRKNEAVLLGAVGGPKWDKCKGDKRPESGLLKLRESLGLF
                     ANLRPATMYESIKEASPLRTDIVEKGIDFVVVRELTGGIYFGERGRKIIDGIENAYDV
                     EIYNENEIRRIGKRAFEIARNRNKKLISVDKANVLESSRLWRSIMEELAKEFEDVELS
                     HMYVDNAAMQVVKDPSQFDVIVTNNIFGDIISDEASMITGSIGMLPSASLREDSFGMY
                     EPIHGSAPDIAGKDIVNPIATILSVSMMLRHSFNLEEEAKCIEDAVQSVLNKGYRTID
                     IYNGVGNVVGTRAMGELIVNEI"
     gene            complement(2055..2546)
                     /gene="leuD"
                     /locus_tag="PC465_003117"
     CDS             complement(2055..2546)
                     /gene="leuD"
                     /locus_tag="PC465_003117"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HDF2650399.1"
                     /translation="MIANGSVFKFGDNIDTDVIIPARYLNIADYKELATHCMEDIDDK
                     FISKVKKGDIIVATKNFGCGSSREHAPIVIKESGVSCVIASTFARIFFRNSINIGLPI
                     LECEEAANNIDEGDNIEVDFSTGVIKNITKGKEYKAEPFPEFMQNIILNEGLINSIKA
                     NRG"
     gene            complement(2561..3838)
                     /gene="leuC"
                     /locus_tag="PC465_003118"
     CDS             complement(2561..3838)
                     /gene="leuC"
                     /locus_tag="PC465_003118"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HDF2650400.1"
                     /translation="MGMTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIR
                     EFEKLGIEDVYDKTKVVMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGI
                     EHVLLPEKGIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGA
                     IKFVLKNKPNKWISGKDIILHIIGEIGVDGALYKSMEFCGDGVEYLSMDDRFTICNMA
                     IEAGAKNGIFPVDDKTMEYINSHKCSTMTKDVNIYEADEDAVYDEVYEIDLAKLKETV
                     AFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIF
                     PGTQKVYLEAIEKGYITTFIEAGAAVSTPTCGPCLGGHMGILAAGEKSISTTNRNFVG
                     RMGHVDSEVYLASPAVAAASAITGKISKPSEII"
     gene            complement(3795..5537)
                     /gene="leuA"
                     /locus_tag="PC465_003119"
     CDS             complement(3795..5537)
                     /gene="leuA"
                     /locus_tag="PC465_003119"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HDF2650401.1"
                     /translation="MKCGKYKKYDKMQIVNRKWPDNEIFKAPIWCSVDLRDGNQSLPT
                     PMSVNEKVRMFKMLIDTGFKEIEVGFPSASNTEYTFLRKLIDENMIPDDVTIQVLTQS
                     RAHLIEKTFESIRGCKKAIIHLYNSTSVLQRDVVFNMSKQEIIDIAVEGAKLFNEEVK
                     KYPETEFTFEYSPESFTGTEMDYALEICEAVIDVWKPTPQKKVIINLPSTVEMATPNV
                     YADQIEWFCKNISCRDSIILSLHTHNDRGTCTAASELGLLAGADRLEGTLFGNGERTG
                     NMDIVNVGLNLYTQGIDPELDFSNIDKIIGIYEDCTKLMVHDRHPYAGNLVHCAFSGS
                     HQDAIRKGMIAMKNRDNDYWEVPYLPIDPHDIGREYKEIIRINSQSGKGGAVYIMETD
                     YGFMIPKNMHSDFGNVVKMESDRIGEELSSEAIFNLFKKEYIEVESPYKVKKYKIKSM
                     DELNYENDDSNDTNMIEMTARISYMGNEQRIVGIGNGPVDSFNNALKQCGMKDYKFRY
                     YWEHALEEGSHSRGVAYVGIEHNNEVYFGVSISENINTAAINALMNAINKSYIEEEIK
                     NGDDYDAENISQTC"
     misc_binding    complement(5661..5907)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(6055..6501)
                     /locus_tag="PC465_003120"
     CDS             complement(6055..6501)
                     /locus_tag="PC465_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650402.1"
                     /translation="MSKNKFIYMNYYDNGYFKKGMTIYMVLALIILATIFIYSTTILY
                     ILCIITAVFLFKQGRDFSNKYEGKVYITLDNHSILINNQCIFSIKSKQSQKFNYKIIE
                     KIEVVKNILNIYTDESNYKIRLRALSLEDEKKLLNIIDEKMKKFKA"
     gene            complement(6522..7241)
                     /locus_tag="PC465_003121"
     CDS             complement(6522..7241)
                     /locus_tag="PC465_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HDF2650403.1"
                     /translation="MKKSIMDVHCHTLISGHAHSTFKENVEEASKKNIKYLGISDHGP
                     NMPGGPHPFYFYNLHLLPREVQGVKILRGIEGNIMDYNGNLDVQEDMLQHLDYIIASL
                     HRPCIASGTKEENTNAILKVMDKPKVKIIGHPDDSRYPLDYEPIVKKAKDKNILLEIN
                     NSSLSSNSHRTGTWENVSHMLTLCKTYGARVILGTDSHICYSIGEFENAEKVLEAVDF
                     PDELVINYHEDEIIEFFDINF"
     gene            complement(7359..8633)
                     /locus_tag="PC465_003122"
     CDS             complement(7359..8633)
                     /locus_tag="PC465_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HDF2650404.1"
                     /translation="MFIMENDLTMQELLDQQEQVFSKVKVGELTTGKITAVRNDEVQL
                     GLDYGFDGIIPISELNIEKNQYIEDIYHIGDEITAVITKVSQKDGTITLSKLQLDKRN
                     DFAELQKAYDEHRIITVNVEKNIDKGVFANYNTYTFFIPISQLDTKFITDTSKFVGLN
                     LEVYIKELDVRKNRLVASHRDVLQERINKEREERRAQIKAEKEAERARIKQEREEEKA
                     RIKAAKEDLFNSLEVGQKRDGKVTKIMPYGAFVDIGGIEGLAHINNLAWTRVESVEDV
                     VSEGQEVEVYVLDVNKETKKIALALKDINNDPWDLIAKEVQIDDVVNAKVLRIIEKGA
                     FVQIKEGVDAYLPISELSDTRVAKVTNVVNIGDEVKVKILDFKPKTKRMLVSIKEATR
                     EPEEDITEYLEVEESLGSIGELFKDKFKDLEV"
     gene            complement(8833..10200)
                     /locus_tag="PC465_003123"
     CDS             complement(8833..10200)
                     /locus_tag="PC465_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2650405.1"
                     /translation="MENSNTNLGSESVGKLLFKLATPAIIAQIVNVLYNIVDRIFIGR
                     MENGEVAMAGVGVAFPIIIIITACSYLIGMGGGPLAAIKMGEQNNDEAEKIMSNSFSV
                     LVILAILLTIGFKIGKEPLLWMFGASESTIGYSMDYLNIYLIGTVFVQISMGMNTFIN
                     TQGFATTGMMTVAIGALINIILDPIFIFGFNMGVKGAALATIIAQGVSAIWVLMFLFG
                     KKSILKIKKKYMIPKASIILPVLGLGISPFIMQSTESLVLIALNSKLQMYGGDLAVGS
                     MAIMSSIMQILMLPNMGVTQGAQPIISYNYGSGQLDRVKKTFKLCLLSCFTYSTILWL
                     LLMIFPAFFVSIFNKNPQLLSMTSWSIKIYFAGAFMFGIQIACQQTFLALGKATISLV
                     LALLRKIVLLIPLIFILPTFFNEKLFAVILAEPVADITAATITAISFFIFYKCFLSKP
                     KAIKE"
     gene            complement(10450..10914)
                     /locus_tag="PC465_003124"
     CDS             complement(10450..10914)
                     /locus_tag="PC465_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HDF2650406.1"
                     /translation="MSLRIGGNSLGYLHILILSMVPVTELRGAIPIGIAMGLNPIWVY
                     VFSVIGSTLVSIPLILTFRHVLQFLRGKKLFKGIADVIDRKINSRMKKLKSVSIIGII
                     LFVGIPLPTTGTWTASAIASILKMRIKDAFMGVFLGNLLSGVIVSALSLHII"
     gene            complement(10919..11548)
                     /locus_tag="PC465_003125"
     CDS             complement(10919..11548)
                     /locus_tag="PC465_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HDF2650407.1"
                     /translation="MKKSVLLLDVDYTVINTDSMIDFFIYSLKNKTFKTIIKLPYIIF
                     ILFMYLIRMIPLKKAKEAIFYPIVDFSEEDLKKFFDDCIMKKINESMKKVIYKNKEED
                     NVIIMITASPYAYMKYFKYYGLADEVIGTEFFYENSRYKNQFIGENCKGIEKVKRIKA
                     VLGKLGIEIDYENSYAYSDSKSDLPMLSLTKNAFLVSKKDGEVIEQINS"
     gene            complement(11582..12469)
                     /locus_tag="PC465_003126"
     CDS             complement(11582..12469)
                     /locus_tag="PC465_003126"
                     /EC_number="2.4.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="HDF2650408.1"
                     /translation="MKQTNTSIRLLTKISDYIKLMRIKQYIKNFFVFSAIIFSNNILN
                     INLFLNTFIAFVCFCLMSSSVYALNDAIDMDKDKKHPKKCNRPVASGRISKKSANILF
                     VVLALISVCLSTVVSFNLSIILSLYLINNILYSLKLKNIILLDVFSISLGFILRVYAG
                     CVAISVSLSNWIILCTFFLSLYLALGKRKKEIETLRDDAVEHRKILEDYDIENLNQMM
                     IVILSSTIVCYALYSTSNPEKPHMIFTTIFVVYGVLRYNYIINTTNENNPTDIVLKDN
                     ALKINVILWIITCLIILIF"
     gene            complement(12498..13736)
                     /locus_tag="PC465_003127"
     CDS             complement(12498..13736)
                     /locus_tag="PC465_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650409.1"
                     /translation="MDGDILMSKILKYKNEMFLFILVVITYLIITKIFFSKTTIFYDL
                     NNTYDVLLDTDTGVLFNLNVFAISQDNSKHILFSAIISIFAYPIYLFCTSIANPGTTD
                     FNSAYGFGLICLQIITSAMSITLVFNHIKKIKMQRLTLILLTMIMIFSFPQLFMTLNV
                     ERFIYSQFSLIFFIVIANKMKGKNSYLVELAAIPLFGITISNIYLYFFNMIFEFKLKI
                     GKMLKHLITFILMAYICVVSTKSYESFMNLGNVIQYDTKFISGEPILEKIAMIIERLL
                     YSVFYFPGASIKKGLFLQNGEVATIPVILTLLALCFCVLSVIENSEKRVPKLCMGIII
                     FNLTLHGIVGYNLVNSSIMAINFSFAVIILLAYFTKALRKNEKNMYNIFLSLLLVTIV
                     ISNVNGFIEILNIGIKSYPV"
     gene            complement(14120..14644)
                     /locus_tag="PC465_003128"
                     /pseudo
     CDS             complement(14120..14644)
                     /locus_tag="PC465_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437122.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
     gene            complement(14830..15216)
                     /locus_tag="PC465_003129"
     CDS             complement(14830..15216)
                     /locus_tag="PC465_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2650410.1"
                     /translation="MLNKKLPDSEFKIMKYIWNTGYKTVISKDVADEMEKIYKWKQTT
                     TLTLLLRLTKRGFLASQKIGKHTHYTILIKEKEYLKSETKKLFGGLHNNPLSQLISKL
                     HDKEEVSIDKIDALEEWLRSLQEDEE"
     gene            complement(15256..15537)
                     /locus_tag="PC465_003130"
     CDS             complement(15256..15537)
                     /locus_tag="PC465_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2650411.1"
                     /translation="MKEKYKWRKSTTEILLGRLVKMRILKKKRAGFQLNYEVLVTKKE
                     YLDVIKEEKDVSKYDNFFTQVFTTIHKKEEKTEKQIKVFIESMQKLGKK"
     regulatory      15853..15950
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            16005..16181
                     /locus_tag="PC465_003131"
     CDS             16005..16181
                     /locus_tag="PC465_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650412.1"
                     /translation="MFKNKMDKCTHMLTAYISSSYDYCNFLDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            complement(16386..16529)
                     /locus_tag="PC465_003132"
     CDS             complement(16386..16529)
                     /locus_tag="PC465_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650413.1"
                     /translation="MSEFLLGVLASLTASFITYIISRKVKSHSGRSDFELDVKIKFNK
                     KRH"
BASE COUNT         5485 a         2978 c         1712 g         6582 t
ORIGIN      
        1 ataactaatt tatttttatc ttgtattttt attgtatttt taaattttat tttttctaaa
       61 tataaaattt atgttttaaa atgtaaaatt tttatttaat caaagttcaa tatattccac
      121 tttttctttc gattcttcaa aaaaccattc ttcattagaa aaatcacctt ctgcaatttg
      181 tccaataggc attttcatat actttccagt tgctgtcact gctatatctc catttggtag
      241 aattatttct cctgtacctt caaataattt tctgttttct ttagttattc ttccaacaac
      301 ttttatagta gcatctgttg gtactggttt cttatatttc aactctaaag atactgttac
      361 tccccatatt tggtcatcat ttatacttac agctcttcca atagtctcat ccaatattgc
      421 agcagacata cctccatgaa ctctcccagg ataactttga tgccaatcct ttgtattaca
      481 aattgataca agctctccat tttcaagttc ataaaaatct gctttaagtc ctagctcatt
      541 ttgtgttcca caaactaaac aagatttact actattttgc ttcttcaaaa ctttatactt
      601 tgccaaaaaa tccatctcct aaccgacatt agtagtcgct taatattaaa taattctaaa
      661 atatattata taatattaat aaaatccctg caaacttcta ataataaaaa taggctactt
      721 caatatgata agtttaattt aaagtattat tttccaaaaa ataactttat caaaatagaa
      781 actcaaagta gatataagcc tctttttcgt tattaaaata gtaaaaatat attttactta
      841 atataaaaaa gagtgtctca ttaactaata aagtttattt tgagacaccc ctcataaaac
      901 aaattatact acaatagatt tttactaatt ctacaagtta tatattcaaa ttatattatt
      961 caaattaaac tataattcta aatttcattt actattaatt cgcccattgc tcttgttcct
     1021 acaacatttc ccacaccatt atagatatca atagttctat aacctttatt gagtacactt
     1081 tgtacagcat cttcaataca cttagcttct tcttctaagt taaaactatg tcttaacatc
     1141 atgcttacag atagaatagt cgcaattgga tttacaatat cttttccagc tatatcaggt
     1201 gcacttccat gtattggttc atacatacca aaactatctt ctctaagtga tgctgatggt
     1261 aacataccta tagaacccgt aatcatagat gcttcatcag atattatatc tccaaatata
     1321 ttattagtca ctattacatc aaattggcta gggtctttta caacttgcat agcagcatta
     1381 tcaacataca tatgtgacag ttctacatct tcaaactctt tagctaattc ttccattata
     1441 cttctccaaa gtcttgaact ctcaagcaca tttgccttat ctacacttat aagtttttta
     1501 tttctatttc tggctatttc aaaagctctc ttaccaattc ttcttatttc attttcgtta
     1561 tatatttcta catcataagc attttcgata ccatcaatga tttttcttcc acgttctcca
     1621 aaataaatgc cccctgttaa ttcccttaca acaacaaaat caatgccttt ctcaactata
     1681 tccgttctaa gtggtgaagc ttcttttata ctttcataca ttgtagctgg tcttaaattt
     1741 gcaaataaac ccaatgactc tcttaatttt aaaagaccag actctggtct tttatctccc
     1801 ttacatttat cccactttgg tcctccaaca gcaccaagca atacagcttc gttttttcga
     1861 caagtttcaa cagttttatt aggtagaggt tctccagttt catcaatcgc gcatcctcca
     1921 gctaatacat attcacaatc gaatctatga ttaaatttac aacaaatttt atttagaacc
     1981 tttatacctt catctataat ttccggtcca acaccatcac cttttatgac tgctatatta
     2041 caattcatac tccactaccc cctatttgct tttattgagt taattaagcc ttcatttaat
     2101 ataatatttt gcataaactc aggaaatggt tctgctttat attcttttcc ttttgttata
     2161 ttttttatca cacctgtaga aaaatctact tctatattat ccccttcatc tatgttattg
     2221 gcagcttctt cacattcaag tataggaagc cctatattta tagagtttct aaaaaatatt
     2281 ctagcaaaag tagaagcaat cacacaggat actccacttt cttttattac aattggtgca
     2341 tgttctcttg atgaaccaca accaaagttt ttagttgcaa ctataatatc tccttttttt
     2401 accttagaga taaatttatc atcaatatcc tccatacaat gcgttgctag ttctttataa
     2461 tcagctatat ttaaatatct agctggtatt attacatctg tatctatatt gtcaccgaat
     2521 ttaaaaacac ttccattggc aatcataaat tttacctccc ttaaattatt tctgatggtt
     2581 ttgatatttt tccagttata gctgatgctg ctgctacagc tgggcttgca agatacacct
     2641 ctgaatcaac atgccccatt cttcctacga aattcctatt tgttgttgaa atggattttt
     2701 ctcctgctgc aagtataccc atatgtcccc ctagacatgg accacaagtt ggtgtagaaa
     2761 ctgctgctcc tgcctctata aaagtggtaa tatacccttt ttctatagct tcaagatata
     2821 ctttttgagt tccaggaaat atcataactc taactccatc tgctactttt ttgcctttca
     2881 ttatctcagc tactacttca aggtctgata ttcttccatt tgtacaagag cctattacaa
     2941 cttggtctat ctttatatcc ttatctatct catctactgt tctagtattt tcaggaagat
     3001 gaggaaaggc tactgtttct tttagtttgg ctaaatctat ttcgtatact tcatcataga
     3061 ctgcatcttc atctgcttca tatatattta catcttttgt catagttgaa cacttatgtg
     3121 aatttatata ttccatagtc ttatcgtcta ctggaaaaat tccatttttt gctcctgctt
     3181 ctattgccat attacaaata gtaaatctat catccataga taagtattct actccatctc
     3241 cacaaaattc cattgacttg taaagtgctc catcaacacc tatctcccct attatatgaa
     3301 gtattatatc tttaccactt atccatttat ttggtttatt tttcaaaaca aattttattg
     3361 ctccaggaac cttaaaccaa cattttcctg tagccatacc tgctcccata tcagttgaac
     3421 ctacaccagt agaaaatgct cctaatgctc catatgtgca agtatgagag tcagcaccta
     3481 taattacatc tccagcagtt actatacctt tttcaggaag aagaacatgc tctattccca
     3541 tatctcctac atcaaaaaaa tttacaactc cttttgattt tgcgaaactt cttgtaaatt
     3601 tacattgttc tgcactcttt atatctttat taggtgtaaa gtggtctaaa accatcacta
     3661 ctttagtctt atcataaaca tcttcaattc ctaatttttc aaattctcta atggctactg
     3721 gtgatgttat atcattacct aaaactacat ctaaatctgc ttcgattaat tgccctttct
     3781 taacttcatt taatttagca tgtttggcta atattttctg cgtcatagtc atccccattt
     3841 tttatttcct cctcaatata acttttattt attgcattca taagtgcatt aatagctgct
     3901 gtatttatgt tttccgatat acttacacca aaatagactt cattattgtg ctctattcct
     3961 acataagcta cccctcttga atgtgaccct tcctctaatg catgttccca gtaatatcta
     4021 aatttataat ctttcatgcc acattgcttt agtgcattat taaatgaatc tacaggtcca
     4081 tttcctatac caacaatcct ttgttcattt cccatataac ttattcttgc agtcatctca
     4141 atcatgttag tatcattaga atcatcattt tcatagttta attcatccat tgattttatt
     4201 ttatacttct taactttata agggctctca acttcaatat attctttctt aaacaaatta
     4261 aatattgctt cactactaag ttcttcccca attctatcag attccatttt gactacattt
     4321 ccaaaatcag aatgcatatt cttaggtatc ataaatccat aatctgtttc cattatataa
     4381 acagctcctc cttttccaga ttggctattt atccttataa tttctttgta ttctcttcca
     4441 atatcatgag ggtctattgg taaatatgga acttcccagt aatcattatc tctgtttttc
     4501 attgctatca tgccttttct aatagcatct tgatgtgaac ctgaaaaagc acaatgtaca
     4561 agattacctg catatggatg tctatcatgt accataagtt ttgtacagtc ttcatatata
     4621 cctattatct tatctatatt gctaaaatct agctctgggt ctattccttg tgtataaaga
     4681 ttaagtccca catttactat atccatattc ccagttcttt caccatttcc aaatagtgtt
     4741 ccttcaagtc tatcggcacc agccaataat ccaagttcac ttgcagccgt acaagttcct
     4801 ctatcattgt gagtatgcaa acttagtata atagaatccc tacaacttat atttttacaa
     4861 aaccattcta tttggtctgc atatacgttt ggtgttgcca tttcaactgt tgatggaaga
     4921 tttattatta cttttttttg aggagttggt ttccaaacat ctatcactgc ctcacatatt
     4981 tcaagtgcat aatccatctc tgttcctgta aaactctctg gtgaatattc aaaagtaaat
     5041 tctgtttctg gatatttttt tacttcttca ttaaataatt ttgctccttc aactgctata
     5101 tctattattt cttgtttact catattaaaa accacatctc tttgaagaac agatgtagag
     5161 ttatataaat gtataattgc ttttttacat ccccttattg attcaaatgt tttttctata
     5221 agatgagccc tagattgtgt aagtacttgt atagttacat catctggaat catattctca
     5281 tctattaatt ttcttaaaaa tgtatactct gtatttgatg ctgatggaaa tcctacctct
     5341 atttctttaa atcctgtatc aataagcatt ttgaacattc tgactttttc atttacactc
     5401 ataggtgttg gcagtgactg atttccgtct cttaaatcga cactacacca aattggagcc
     5461 ttaaatattt cattatctgg ccatttacga tttactattt gcattttatc atatttttta
     5521 tactttccac acttcatgtt atttccccct ttttctgttt tttgtattca gtatacctca
     5581 tatcgacgca atcctgcaca attcataagg ataaatgtca attttatcat tagaataaaa
     5641 aaaacctcat ctctaataaa attagagacg aggttttgct cgcggtacca ctctatttag
     5701 ctttctaaaa agctccctta gtaatagcca atacaataat tataatgact atatttccta
     5761 taacgtggaa ttactccgat tattctaaga tttaaatctt agaaaacagc tcctagacaa
     5821 gttcagaact atcaactact aaatcacacc atcctttagc tctctgaaag tttcattgtt
     5881 cttactactt ctattcatca cttttttaat catttaaatt ttctaaatat tttgatttaa
     5941 tagttattat atacacatta aaatgtattg tcaacacaaa aaataattat ctcaattttt
     6001 tatttttgat aagcaattct ataaaacatg ctaactattg aaaacagtat gatattatgc
     6061 cttaaacttt ttcatctttt catctatgat attcaataat tttttttcat cttccaaact
     6121 caatgccctt aatctaattt tataattaga ttcgtcagtg tatatattta atatattttt
     6181 tactacttct attttttcta ttatcttata attaaacttt tgactttgtt tagattttat
     6241 actgaatata cattgattat ttattaatat tgaatgatta tcgagagtaa tatatacttt
     6301 tccctcatat ttatttgaaa aatcacgacc ttgtttaaat agaaaaactg ctgttattat
     6361 acataaaata tataatattg tcgttgaata tataaaaatt gtagctaaaa ttataagtgc
     6421 taaaaccata tatatagtca ttcctttttt aaaataacca ttgtcataat aattcatata
     6481 gataaactta tttttactca aattttttca ctcccaagat tctaaaaatt tatatcaaaa
     6541 aattctataa tttcatcttc atgataattt atgactaatt catctggaaa atctactgct
     6601 tctaaaactt tttctgcatt ttcaaattct cctatagaat aacatatatg agagtcagta
     6661 ccaagaatta ctcttgcacc atatgtttta cacaatgtca acatatgact tacattttcc
     6721 caagtacccg ttctatgaga atttgaactt aatgatgaat tatttatttc taaaaggata
     6781 tttttatctt tagctttttt tactataggt tcataatcta aaggatacct actgtcatct
     6841 ggatgtccaa ttatttttac cttaggttta tccataactt ttaaaatagc atttgtattt
     6901 tcttcttttg taccagaagc tatacaaggt ctatgcaaac ttgcgattat ataatccaaa
     6961 tgttgcaaca tatcttcttg aacatctaaa ttaccattat aatccattat atttccttct
     7021 attcctctaa gaatctttac gccttgcact tcacgtggaa gcaaatgcaa attataaaaa
     7081 tagaatggat gtggtcctcc tggcatatta ggtccatggt ctgatattcc taagtatttt
     7141 atattcttct tactcgcctc ttcgacattt tccttgaaag tactatgtgc atgtccactt
     7201 attagagtgt gacaatgtac atccataata gactttttca ttaaatttcc tcctaatatt
     7261 ttacataaat tcgtgaaaat agctaaaggg ctatttcaaa actaaagctg tcataataga
     7321 cagtgtaacg ttttaaaaca gccccatttt caattatttt acacttctaa atctttaaat
     7381 ttatctttaa ataattctcc aatacttcct aaagattcct ctacttctag gtattctgtt
     7441 atatcctctt ctggctctct agttgcttct tttattgaaa ccaacattct tttagtcttt
     7501 ggtttaaaat caagaatctt aactttaacc tcatctccaa tattaacaac attagtaact
     7561 ttagccactc tagtatcact caattcagat attggtaaat acgcatctac accttcttta
     7621 atttgaacaa aagccccttt ttctattatt ctaagaactt tagcattgac aacatcatca
     7681 atttgtactt cttttgctat taaatcccaa gggtcattat ttatgtcttt taatgccaag
     7741 gcaatttttt tagtctcttt atttacatcc aacacataaa cttctacttc ttgtccctct
     7801 gaaacaacat cttcaacact ttcaactctt gtccaagcta aattatttat atgtgctaat
     7861 ccttcaatcc caccaatatc cacaaatgca ccataaggca ttatctttgt caccttacca
     7921 tctctttttt gtccaacttc aagagaatta aataagtctt ctttagctgc tttgatacga
     7981 gccttttctt cttctctttc ttgcttaatt cttgctcttt cagcttcttt ttctgcctta
     8041 atttgagctc ttctttcttc tctctcttta tttatacgct cttgtaatac atctctatga
     8101 gatgctacaa gtctattttt tctaacatcc aattctttta tataaacttc taagttaaga
     8161 ccaacaaatt tagatgtatc tgtaataaat tttgtatcaa gttgagaaat tggtataaaa
     8221 aatgtatatg tattgtaatt agcaaataca cctttatcta tattcttttc aacatttaca
     8281 gttattattc tatgttcatc ataagccttt tgtaactcgg caaaatcatt tcttttgtca
     8341 agttgtaatt tagataaagt tattgtacca tctttttgag atacttttgt tattacagca
     8401 gttatttcat cacctatgtg gtatatatct tctatatatt gatttttttc tatgttcaat
     8461 tcacttatag gtattattcc atcaaaccca tagtctaatc ctaattgtac ttcatcattt
     8521 ctcactgcag ttatttttcc agttgtcaat tctccaactt tcactttgct gaatacttgt
     8581 tcttgctggt caagtaattc ttgcattgtt aaatcatttt ccattataaa catcctttcc
     8641 tcttattgat tatcatatct gtaaatatta taccattaat attgcaaata cttacatttt
     8701 tcttactata atttttaaaa taaattcaac ttcatatatt tatacattat agaaaatatc
     8761 ttattaaatt aaaatacaaa ttctaatttt tatctaataa aatattttca taaaaaattt
     8821 atattgtata tcttattctt ttattgcttt aggttttgat agaaaacatt tataaaatat
     8881 aaagaaagaa attgctgtta tagtagcagc tgttatatct gcaactggct ctgctaaaat
     8941 tactgcaaaa agtttttcat taaagaatgt tggaagtata aatattaaag gtattaaaag
     9001 tacaatcttt ctaagtagag ctaaaaccaa agatattgtt gcttttccaa gtgctaaaaa
     9061 tgtctgttga caagctattt gaatcccaaa cataaaagca ccagcaaaat atatttttat
     9121 actccaacta gtcatactaa gtaactgcgg attcttatta aatatactaa caaaaaatgc
     9181 aggaaatatc attaataaaa gccataaaat agtagaatat gtaaaacatg acaataaaca
     9241 caacttaaat gtctttttta ctctatcaag ttgacctgaa ccataattat aacttattat
     9301 tggttgtgct ccttgtgtaa cccccatatt aggaagcata agaatttgca ttatactgct
     9361 cattatggcc attgaaccta ctgctaaatc tcctccatac atttgtaatt tactatttaa
     9421 ggctataagt actaaacttt ctgtagattg cattataaat ggagagattc ccaagccaag
     9481 cactggtaag atgatacttg cttttggtat catatacttc ttttttattt taagtatact
     9541 tttctttcca aagagaaaca taagcaccca aatagcagaa acgccttgtg caattatagt
     9601 agctaatgca gctcctttta cacccatatt aaagccaaat ataaaaatcg ggtcaagtat
     9661 tatgtttatt aaagcaccta tagcaactgt catcattcca gttgtagcaa acccttgggt
     9721 atttataaaa gtattcatac ccattgaaat ctgaacaaac actgtaccta ttaaataaat
     9781 atttaaatag tccattgaat atccaattgt agattcactt gctccaaaca tccaaagtaa
     9841 aggctctttt ccaatcttaa aacctatagt caaaagtatt gctaaaatca ccagtacaga
     9901 aaaactgtta ctcattattt tctctgcctc atcattgttt tgctcaccca tttttatagc
     9961 agctaatgga cctcctccca taccgattaa ataactacat gcagttatta taattattat
    10021 tggaaatgcc actccaacac cagccatagc aacttctcca ttttccattc taccaataaa
    10081 aatcctatcg actatgttgt ataaaacatt tacaatttgt gcgataatag caggtgtagc
    10141 aagtttaaat aataatttac ccacactttc actacctaag ttagtgtttg aattttccat
    10201 tttaaaacct cctcaatcca ataattaaaa tgtatcacta aaattttatt ctatataaaa
    10261 atttcatttt attagcagac aaatttagag tactttccct acaagtaata ctatactata
    10321 tttcttttgc catagtaaac attttagaac taactgaagt taaatacttt atctcatttt
    10381 ttatttatta ttaaaaattt ttcacatata ctcataaaaa aactatccaa gtatattact
    10441 tagatagttt tatattatat gtaaagaaag agctgaaact ataacccctg ataacaaatt
    10501 accaagaaat actcccataa aagcatcttt tattctcatt tttaatatgg aagctatagc
    10561 agatgcagtc catgttcctg tagttggcag tggtatacct acaaatagta ttataccaat
    10621 tatcgaaaca ctttttaatt tcttcattct tgagtttatt tttctatcaa ttacatcagc
    10681 aatcccttta aatagtttct tccctcttaa aaattgcaat acatgtctga atgtcaatat
    10741 caagggaatc gataccaatg tagaacctat tacactaaat acataaaccc atataggatt
    10801 taagcccatt gcaataccta taggaatggc tcccctcaat tctgttacag gaaccataga
    10861 taaaattaat atgtgtaaat atcccaaact attccctcct attctaagtg acattaagtt
    10921 atgaatttat ttgctctata acctcaccat cctttttact aactaaaaat gcatttttag
    10981 tcaatgaaag cattggtaaa tcactcttag agtctgaata tgcatatgaa ttttcataat
    11041 caatctctat cccaagttta cctaatacag cctttattct ttttactttt tcaattccct
    11101 tacagttttc tccaatgaat tgatttttat atcttgaatt ttcataaaaa aactccgtgc
    11161 ctataacctc gtctgcaaga ccataatact taaaatattt catatatgca tatggagatg
    11221 cagttatcat aattataaca ttatcttctt ctttattttt gtaaataacc tttttcatag
    11281 attcgttaat ttttttcatt atgcaatcat caaaaaactt ttttaaatct tcttcactaa
    11341 aatctactat tggataaaag attgcctctt ttgccttctt caaaggtatc attctaatta
    11401 aatacataaa tagaataaaa ataatgtatg gcaactttat aatagtttta aaggttttat
    11461 tttttaaaga gtaaataaaa aaatctatca tgctatcagt atttataaca gtataatcta
    11521 catcaagtaa taatacactt tttttcataa gtatttcccc atcctatcac taaaaatatc
    11581 actaaaaaat caatattatt aaacatgtaa ttatccataa gattacgttt atttttaaag
    11641 cattatcttt taggacaata tcagtaggat tattttcatt tgtagtgtta attatataat
    11701 tatatctaag tacaccataa actacaaata ttgttgtaaa tatcatatgt ggcttttctg
    11761 gattacttgt agaatacaat gcataacata caattgtaga acttaatata actatcatca
    11821 tttgatttag attttctatg tcataatctt ccaatatttt tctatgttca actgcatcat
    11881 ctcttaaagt ttctatttct tttttacgtt ttccaagagc taagtacaga gataagaaaa
    11941 atgtacataa aattatccaa tttgataaac taacacttat ggctacacat cctgcataaa
    12001 ccctaagtat aaaaccaaga gatattgaaa acacatctaa tagtattata ttctttagtt
    12061 taagagaata taatatattg tttatcaaat agagactgag aattatagaa agattaaaac
    12121 taacaactgt tgataaacag actgaaatta aagctaatac tacaaatagt atattagcac
    12181 tttttttgct tattcttcca cttgccactg gtctattaca ttttttagga tgttttttat
    12241 ctttatccat gtctatagca tcattcagtg catatactga tgatgacatt agacaaaaac
    12301 acacaaacgc aataaacgta tttaaaaata aatttatatt tagtatgttg tttgaaaaaa
    12361 ttatagctga aaatacaaag aaattcttta tatattgctt tattctcatt aactttatat
    12421 aatctgaaat tttagtaaga agccttatac ttgtattggt ctgtttcata aacttactac
    12481 cctttcaata ttatttttta aacaggatat gattttatcc ctatgtttaa aatttctata
    12541 aatccattga cattactgat tactatagta accaataaca gcgatagaaa tatattatac
    12601 atattctttt cattttttct aagcgctttc gtaaagtaag ccaataaaat tataactgca
    12661 aaactaaaat ttatagccat aatacttgaa ttgactagat tatatcctac tataccatgt
    12721 aaagttagat tgaatataat tattcccata catagcttag gaactctttt ttctgaattt
    12781 tcaataactg ataaaacaca aaaacataaa gctaataatg taagaattac tggtattgta
    12841 gcaacttctc cattttgcaa aaataaccct tttttaatac ttgctccagg aaaataaaaa
    12901 accgaataca ataatctctc tataatcatt gcaatctttt ccaaaattgg ttctccactt
    12961 ataaatttcg tatcatactg tattacattt ccaaggttca taaaactctc ataagacttt
    13021 gttgaaacta cacaaatata tgccattagg ataaatgtaa ttaaatgttt taacattttt
    13081 cctattttta atttaaactc aaatatcata ttaaaaaaat acaaatatat attactaata
    13141 gttattccaa atagaggaat agctgctaat tctactaaat aagaattttt tcctttcatc
    13201 ttatttgcaa taactatgaa aaatattaat gaaaattggc tatatataaa tctctctaca
    13261 tttaaagtca taaataactg tggaaaagaa aatatcatta tcatagtaag taaaattaaa
    13321 gttaatctct gcatttttat ctttttaata tgattaaaga ctaaagttat tgacatagca
    13381 ctagttatta tttgtagaca aattagtcca aacccatagg cactattaaa atctgttgtc
    13441 ccaggatttg ctattgaagt acaaaatagg tatattggat atgcaaaaat tgatataatt
    13501 gctgaaaaca atatgtgctt actattgtct tgacttatag caaatacatt taaattgaat
    13561 aaaactcctg tatctgtatc taacaataca tcataagtat tgtttaaatc ataaaatata
    13621 gtagtcttag aaaaaaatat cttagttatt attaagtaag ttattacaac taatataaac
    13681 aaaaacatct cgtttttata ttttaatatt ttactcatca atatatcacc atccattcat
    13741 tatataggat ttgctgacac ctacaattta ttccttatat ttaatagcca tcttcataat
    13801 gttcttactt gttttattgt aattgaataa ctctttattt acaaccacaa tatttacttt
    13861 attgatgtta taatcagtca agtattgttt atataacata gattagtgtt gtataaaatg
    13921 agaatttgta agcaatatta atgtaaaata tttgaaaaac tttatataaa aatatacaat
    13981 gttgcttatg gaattaaact ataacaaatt aaagcataat ttaaggagac aaaattataa
    14041 tctgtctcct taaatattaa aactatattt taaaacatta ctaaatacta tacaaatttc
    14101 aaatatagta taaaattaat tagactttaa cactattagc tccatcttct tcccattttt
    14161 taatttcttt taatctatct attataggta aatgctgagt acattcaact tcacattttc
    14221 cacaagatat acattcttta gcttttgcct tactattcat tgtgtaattc caatgtccta
    14281 agccataaac taactttgtc atttcttcat cactcttttt aaacatctgc ttttcattat
    14341 aaaaaagcat ataggctggg gtattaatac cttttggaca tactttacaa taaccacaac
    14401 ctgtacatat ttcgttcata ttcttattta atctagtctc aatatcatgt atatcctcat
    14461 ctgaataaat tctattttcg tctgcaattt tacatgcatc atctatatct tgttttttat
    14521 taaaccctat caaagatata cttatttgtg aaattcctat gttgaatctt aaagctgatt
    14581 ctatagtact ttcgccatct tttgatagaa aagaaagttc tttattatac tttggaatag
    14641 ttcccaaacg acttttagta tttaaaacca ttgatttcac agcattttca ttttttactt
    14701 taatcttgtt gtcagttaaa tgtcagcaaa acattttatc cacaattttt atataacttt
    14761 tccacagttt atccccagct ttatccacaa aaaggtagct actattgagt gctacctttt
    14821 ggcatattct tattcttcat cttcttgcaa acttcttaac cattcttcaa gcgcatctat
    14881 tttatcaata cttacctctt ctttatcatg taattttgat attaactgtg ataaaggatt
    14941 attatgtaaa cctccaaata gttttttagt ttctgatttt aagtattctt tttcttttat
    15001 taatattgta taatgtgtgt gtttacctat tttttgagaa gctaaaaaac ctcttttagt
    15061 taaccttaat aaaagtgtta gtgttgtagt ttgtttccat ttatatattt tttccatttc
    15121 atctgccaca tcttttgata ttacagtttt ataaccagta ttccatatgt atttcataat
    15181 cttgaactct gaatctggta attttttatt tagcataata tccccttctt tctattaaca
    15241 tataaaaata taaaattatt tttttcctag tttctgcata ctttctataa atacttttat
    15301 ttgtttctct gtcttttctt cttttttatg tatagttgta aatacttgtg taaaaaaatt
    15361 atcatattta cttacatctt tttcttcttt tattacatct aaatattctt ttttagttac
    15421 taatacttca tagtttaatt gaaaaccagc tctcttcttt tttaatattc tcatttttac
    15481 taatcttcca agtaaaatct ctgtagtgct ttttctccac ttatattttt ctttcattgc
    15541 tacttctatt tcttttttag atagagtaga tttttccctt cacatgtact ccatcaacat
    15601 taattcgccc ctgcgtaatt tactttctac ctcttgtcgc tccatttatg tcacttcctt
    15661 aattcatcta acttaaatta ataataggag ctttttaaca caaaaactat aggtaagttt
    15721 taccatatat tctactgttt tagtttgttt ttatatataa aaaatattat tcacatctac
    15781 gaatttattt aattttcaaa caatcttgtt gaacaataac taattctatt gtattatttt
    15841 agttgtagaa taaaactaaa tcggcaaaac tagagaaatt tagtgacgca aagctatagg
    15901 ggctaagact tatataaata tcttatgagt tatgtcagcc agttgccaaa aagatagtgt
    15961 tctttttgtt tttatgaaag ttttttaggg ggataataat ttatatgttt aaaaataaaa
    16021 tggataaatg tacacacatg ttgactgctt atattagcag ttcgtatgat tattgtaatt
    16081 ttttagatac acagttagat gattttatat tagagtacgg agaaaatgta gtagagtctt
    16141 gtttacacca agtgatggta ttggtaagta agtataatta gatagacatt gatttctaga
    16201 gaaccctttt tagttttatc tacttttaaa taatgatatg ataaaaaatt aattaaaata
    16261 gatttataat attcatagtt ttattttttc ttaaaatgcg atataataaa gatgtaaatt
    16321 cgtatcaaaa acaaaaaaag aaactacaat ctattagcct agagtgaagt ttcattaact
    16381 aaatattaat gtcgtttttt attaaacttg atttttacat caagctcaaa gtcactcctg
    16441 ccagagtggc tttttacttt tctggaaata atatatgtaa taaagctagc tgttaaacta
    16501 gctaacactc ctagtaaaaa ttcgctcatt tctccacctc cttcctttta agggatggaa
    16561 tgtagaaaat gaagctccac tcttagattg tagttccaca agattattct tgcattttaa
    16621 ttataacata attttacaat tatcaaatat ctattcttca tattttttat ttatacaata
    16681 tattctatat tgcaataaaa aacattgttt taaatatata tatatatata tacataggta
    16741 tatactaaat atgttaa
//
LOCUS       DAMJXI010000076        16627 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.080, whole genome shotgun sequence.
ACCESSION   DAMJXI010000076 DAMJXI010000000
VERSION     DAMJXI010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16627
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.080"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            182..850
                     /locus_tag="PC465_003133"
     CDS             182..850
                     /locus_tag="PC465_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650414.1"
                     /translation="MSKLESTTEKVEVKWYGYVALILGALFFSGIFKDAPGPLKVLDF
                     NNVLGSFGTLGTINDGVGTLAANFRGDGGTGPRDGWLYALTLIPSVMFALGVVRVIDH
                     LDGMKAAQKLLSPLLKPLLGLPGFAGLTLIASLQSTDAAASMTKELKDDGYIDEKQKA
                     VFCAFQFSGASAITNFFASGAALFPFIGDVPIFIPLALILIMKFVGANLLRLYLNKFD
                     KGEA"
     gene            852..1337
                     /locus_tag="PC465_003134"
     CDS             852..1337
                     /locus_tag="PC465_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HDF2650415.1"
                     /translation="MSEVAKKEVKVKKGNVIDAFIGGARNGFQISTNSMAPNVIFGFA
                     IISVFNLTGLLDVIGTIFTPVMSIFGLPGVAATAIMTIFISMGGASGVIAGLFTAGQI
                     SQAHVAILLPMLLLSGAQIQFMGRLLGTAELKTKYYPHMFVIATLNGCIAMLIMNYFV
                     V"
     gene            1398..2519
                     /locus_tag="PC465_003135"
     CDS             1398..2519
                     /locus_tag="PC465_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 peptidase aminoacylase family protein"
                     /protein_id="HDF2650416.1"
                     /translation="METNKDYIEYVHKVYDYLHTIPEKGFEEYKTSEFVLKELEKMGF
                     ENINKGIAGTGIIVTIDSKKEGPVFAIRADMDALEFIIDGEKKMIHACGHDGHTSMLL
                     TAAKLIKERNLVKRGKLKILFQPGEEKLYGALRVIDSGLLDDVEEMVGMHLRPGQDCR
                     LGKAIPAMYHCASCIMEFTIKGITCHGSKPHLGVNAVDAVCLAVNAINAIRVNPAIPN
                     SIKVTNISVKGETYNNIPDEAFMALDIRAESNDIIEELKEKAIHAVKTAVSSINAEAV
                     LISKDGVPAAEFDEELVNLAEETIKDVLGADASIGIFKNSGGEDFHYYTQKLKCKTTY
                     IGLGADATPGFHNPNVTFDTKALEYGVDIWCRLVEKRLG"
     gene            2800..3990
                     /locus_tag="PC465_003136"
     CDS             2800..3990
                     /locus_tag="PC465_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2650417.1"
                     /translation="MSKYNFDRVIDRVGTDCVKWDFRTNCSTKAQKDGLPFWIADMDF
                     ECAEPIIEALRKKVEHKIFGYSSNDSDKYFNAVCDWYKRRFNWEINRKDIIFSPGVVP
                     AVAILVRILTNSNEGVIVQKPVYYPFEAKIKSNNRDVVNNPLIYENGTYRMDYDDLEE
                     KAKCSNNKVLILCSPHNPVGRVWREDELKKVVEICKKYDLWIIADEIHSDLIRKGFKH
                     TPLQSLCPEYKDKIVTCIAPSKTFNLAGMQLSNIIVNNDELKKKYQEEVTAVGVATSP
                     NPFAIVATIAAYNESEDWLNELNDYLDNNIQFIDEYLKENLPKVKLVYPEGTYLAWLD
                     FTAYGLNEVELEDLMFKKANVLFDEGYIFGKEGIGFERINVACPQSLLKECMDRLKTI
                     FENL"
     misc_binding    4124..4379
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            4438..5439
                     /locus_tag="PC465_003137"
     CDS             4438..5439
                     /locus_tag="PC465_003137"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HDF2650418.1"
                     /translation="MSTIIPKDYKSSLNVIDTQIAIKKLKDFFEMRLSNELNLIRVSS
                     PLFVLPETGANDNLNGEKAVSFDIPFMNKNAEIVQSLAKWKRLALKKYGFEVGSGLYT
                     DMNAIRKNEELDNIHSLYVDQWDWELVIDKSSRNEKTLKDVVKRLYGVFKDTEIFVCS
                     MYEGIKEILPEEITFITSQELEDMYPELSPKEREDKIVKEKKAVFITQIGKTLISGEK
                     HDGRSPDYDDWELNGDILFYNPVLDSALELSSMGIRVDEESLDRQLKLAGCEERKEFD
                     YHKMLLNGELPYTIGGGIGQSRICMYFLQKAHIGEVQVGVWPQDMIQNCSSAGIELL"
     gene            5543..5932
                     /locus_tag="PC465_003138"
     CDS             5543..5932
                     /locus_tag="PC465_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1232 domain-containing protein"
                     /protein_id="HDF2650419.1"
                     /translation="MEFLKIIINIVLDILKKILVRFKNAKFGLVFVFDLLKLPDFMTD
                     KRINIVDKIKVISVLIFTISYFVSGVDIIPEMIAGAFGFIDDAIVLIWSIGIVNEEIN
                     KYRVITKKDKHSNIIENVEFSIKDEEE"
     gene            6093..7301
                     /locus_tag="PC465_003139"
     CDS             6093..7301
                     /locus_tag="PC465_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HDF2650420.1"
                     /translation="MKKKIGLVPKLIIGIIVGILIGSYAPEIIVQILVTVSTLFSAFL
                     KFVIPFIIIGFVTAGIADLATGAGKLLGITTGIAYGSTLIAGLLSFAVSTLIFPNFID
                     ASVASQIGDPEAGMLAPIFTIPLEPMVDVTAAIVFAFVMGLGISALRNHGKGETLFNF
                     FQEFQGIVTKTLSTVIIPLLPLYIAGTFANITIAGEVWTILGVFWKVYLVVIPLHFVY
                     MACQFTAAGVFSGKNPVRMLKNQVPGYLTAIGTQSSAATIPVNVGCAEKNGVSKQIRE
                     FVVPLCATIHLSGSMISITGFTTAVLMMNGMPHGIGVLFPYIAMLGIAMVAAPGAPGG
                     AIMSALPFLPMVGIPSDGGLASLMIALYLTQDSFGTACNVSGDNAIAVVVDKINDGMS
                     KKGNKEEQSA"
     gene            complement(7387..8463)
                     /locus_tag="PC465_003140"
     CDS             complement(7387..8463)
                     /locus_tag="PC465_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2650421.1"
                     /translation="MSTNHGANLYSLSSKYGFSKEEFMDFSSNINPFGTSSLAKQYIV
                     NNIDMVSMYPDPDYIDLKTSISNYCKCSIDNIVLGSGATELISSFIHTINPKQALLLS
                     PAYSEYEKELSKINCSIEKYFAKEEDNFHINLENLIKTINAKDYDLVVICNPSNPTGF
                     AFTKVEVREILKNTDSFLMIDETYVEFTDTDTYSCTQLVDDYSNLFVIRGTSKFFSTP
                     GIRLGYGLISNTNVKNEINKNLDLWNINIIASKMGEIMFSDLDFISNTISLMNTERDY
                     LLKELKNIKSLDIYNTKGNFILCKIKTKELTAKSLREQLLPQKIIIRDCCSFEGLDEY
                     FFRVCILKPNENKLLISSLKAIFK"
     gene            8692..9219
                     /gene="hpt"
                     /locus_tag="PC465_003141"
     CDS             8692..9219
                     /gene="hpt"
                     /locus_tag="PC465_003141"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDF2650422.1"
                     /translation="MYKVTGKMLTEEQIKEKVYELGKKIEEDFKGEDLLVVGILKGAS
                     VFVSDLIRCIDLDVNIDFMSVTSYGNSTESSGTVKILKDLDVDIEGKNVLIVEDIIDS
                     GLTLSNLVAALKTRNPKSLKLCTLLDKPQRRKANIPVDYVGFVIEDKFIVGYGIDYAE
                     KYRNLPYIGIVEDVE"
     gene            9308..10240
                     /locus_tag="PC465_003142"
     CDS             9308..10240
                     /locus_tag="PC465_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HDF2650423.1"
                     /translation="MDIQLNILLFFQNLRNPILNFIFLVFTISTEAPLLILITTIIYW
                     CINKKCGQKILFAIIGNFVVNLGIKEFVKAPRPIGIKGLESLRVSTAGGYSFPSAHTQ
                     TATTFWVSIMTIFKKRYLHLIAAVMVLGVGLSRLYLAVHWPIDVIAGWILGIFFTVVF
                     VKIFDYIDDNKNYILLVVLLIPFIIVAIFLNSPEYFEKFGIIVGFVFGYMVEDRFVKF
                     NTDNNNKKINFSNKNKGSKNIIFSRICRFLVGIVTIGMLYIGIKLFISMLIVTLNMSD
                     STMSIIFMNFIKNTVVVFYGIAGAPALFKLLKLN"
     gene            10302..11528
                     /locus_tag="PC465_003143"
     CDS             10302..11528
                     /locus_tag="PC465_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2650424.1"
                     /translation="MKKVVIIGGGPAGMIAASTACEKGYDVTLIEKNHKLGKKLAITG
                     KGRCNITNACEIEELIENVPTNGKFLYSAFYTFTNDDVISMFNNLGVKTKTERGKRVF
                     PESDKAFDIVNALERQLKSKKVNILLNSKVEKIISKNNKIEKVILNDKKEIKCDSVVV
                     ATGGLSYPLTGSTGDGYKFAISQGHTIIDTKPSLIGIEVQESFTKDLEKLSLRNVEIR
                     VFNSKQKKVYSDFGELEFTRFGLDGPIIKSASCRMKDTRKENYTILLDLKPALDEEKL
                     DKRVQKDFQKYTNKKFEKALDDLLPKKLIPIIINLSEINPNTVVHQISREQRKNLVHL
                     LKNLKFTVKRYRPIEEAIITSGGVKVNEINSSTMESKLVEGLFFAGEVIDIDAYTGGF
                     NLQIAFSTGYLAGFNC"
     gene            11612..11833
                     /locus_tag="PC465_003144"
     CDS             11612..11833
                     /locus_tag="PC465_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HDF2650425.1"
                     /translation="MASNNNNNRTVVPGAKEALNQMKLEIANELGMSNYQQVDKGNLT
                     ARENGYVGGYMTKKLVEMAEQQMAGKSNR"
     gene            12022..12192
                     /locus_tag="PC465_003145"
     CDS             12022..12192
                     /locus_tag="PC465_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650426.1"
                     /translation="MSSVNFEDLKNKFINSDLDEKIRIYTTTEGLSVEQFKELLKYYP
                     IQHLSKLEKALG"
     gene            complement(12285..12746)
                     /locus_tag="PC465_003146"
     CDS             complement(12285..12746)
                     /locus_tag="PC465_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650427.1"
                     /translation="MQIEQLDLETRNKIYCYTKKILRKYQKGITSGKLTADKFADNIL
                     SQDFISSILNEKIVNETNFKISYRNYIETLINIQNENLSNLRKKSTKTAKCFNISQIT
                     QLKNLLSNTGYNLLIPYKYLTARDIEGIVTLINTGSIELGNERIYNYISKA"
     gene            12929..13396
                     /locus_tag="PC465_003147"
     CDS             12929..13396
                     /locus_tag="PC465_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650428.1"
                     /translation="MKMLNGIIKLFYSEIVKTKINNLDSSGYSLRDECKEIRNITLKI
                     DSVFFKLLKLAFGSILLMVAFNLNMVLGIGVFLVGVVYILYKRNMEEQVKEHINNVKN
                     NIDISKITFMDEKGRTGLNALITLLLIGLLTGFNWILVASFVVVFVFTIKNVC"
     gene            13439..15202
                     /locus_tag="PC465_003148"
     CDS             13439..15202
                     /locus_tag="PC465_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="HDF2650429.1"
                     /translation="MTNGSYKMKNLVEISAMVTESTDFFNIKDDIIEKMLEVVHPTKA
                     CVNLFYKNDSKYAYLVCSQTLEYVPQIFPINSLKGAKIDFDTYPEYIHEAVNEKKIIY
                     VENVFEDSRAEGERDLAKAEGYIGRIVFPFIINNVVVGFMTCFLKEDDYITEQDIDFI
                     SSVASLLSLSIEITNKNNNVQILIDKLRGSISAINEATKKLYLNKSIDGFLENLSKQA
                     CNITNSKEALIIINSHHNKDAIVSCYNVEQKKKTNLYPMIDMFLKKESLGGYLNNLKP
                     CSKKGINLESYIYYKLQDKNDTIGCIVCANSKNYTSDDLNILSILSKQVSVGMQLYEH
                     NEKEVKHKVLENELNILNKQQQLIMDKGKMDCNDEKELYFYHKPARVVGGDFYYATKV
                     DDEHIVYIVADVMGHGMVSNYVVAMIKGAFKVLCNQYNTPREIMTNLNRMLYDEFDKM
                     GVFTTCLIGIIDTKENMITVSNAGHYSPVVVKKDGTIENNLNCKKGIPIGIMEDATYE
                     NNTLSMEDYAMVCMYTDGILEIKNSSKEEYGINRLENFLKENFRLNQQLIVENLKLDL
                     KNFSSKDNYDDDILIVMLKDR"
     gene            15210..15818
                     /locus_tag="PC465_003149"
     CDS             15210..15818
                     /locus_tag="PC465_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2650430.1"
                     /translation="MDSNDKKGLKSPEIIIINGSPRINKNCSFIANEVKAMLEECGLS
                     CKIFNIYNMDIEYCTACGFCEKTGYCKFNDDMKPLYKMFDDSKGTIVISPVHFDSISA
                     KLKTVVDRTQAIYASKYVLNKPSIDRSKKRIGMYIAVGGSKSYDSQFKGGQIVMDFFF
                     KSINTKLLHNIYLNNTDDVSYIDNQEFKDIIYKNLKIYIDSI"
     gene            15890..16459
                     /locus_tag="PC465_003150"
     CDS             15890..16459
                     /locus_tag="PC465_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HDF2650431.1"
                     /translation="MKLPIALSNKHVHLSQADIDVLFGAGHELTKFKPLSQPGQYACE
                     EKVDLVGPKGTLKGVRVLGPARAHTQVEISLADGFPLGVKAPIKESGDIAGTPGVKLV
                     GPAGEVEMKEGVIVASRHIHMSNEDAAKFGVTDKQIVKVKTSGPRALVFENVLVRASD
                     SFNLEMHVDMEEGNAAGVKNGDLVELIVD"
BASE COUNT         6508 a         1683 c         2931 g         5505 t
ORIGIN      
        1 taataaaaaa atattatatt tttaaacttg aaaagtaagt aattataagc tatttaatca
       61 ctggaataaa tttacaataa aaaaataaat acaaaggctt tatcattaag gtattggcat
      121 aagttttgct tattaaacaa gtatactaat aaaattcatt taaacaggag ggagaattta
      181 tatgagtaaa ttagaatcaa caacagaaaa agttgaggta aaatggtatg ggtatgtagc
      241 attaatattg ggagcattat ttttttcagg aatatttaaa gatgcaccag gaccattaaa
      301 agtattggat tttaacaatg tattaggttc ttttggaaca ttgggaacaa ttaatgatgg
      361 tgtaggtaca ttagctgcaa actttagagg tgatggaggt actggccctc gagatggatg
      421 gctatatgca ttgacattaa taccatcagt tatgtttgca cttggagtag ttagagttat
      481 agaccactta gatggaatga aggcagctca aaagcttctt agtccactat taaagccatt
      541 attagggtta cctggatttg caggactaac tttgatagct agtttacagt ctacagatgc
      601 agctgcatct atgactaaag aacttaaaga tgatgggtat atagatgaaa aacaaaaagc
      661 tgtattttgt gcatttcaat tttcaggtgc gtctgcaatt acgaatttct ttgcttctgg
      721 agcagcacta tttccattta taggagatgt accaatattt ataccacttg ctttaatatt
      781 aattatgaag tttgttgggg cgaacttact tagattatat ttaaataaat ttgacaaggg
      841 ggaagcttaa catgagtgag gtagcaaaaa aagaagtaaa agttaaaaaa ggaaatgtga
      901 tagatgcgtt tattggagga gctagaaatg gattccaaat aagtacaaat tcaatggctc
      961 caaatgtcat cttcggtttt gctataattt ctgtgttcaa tttaacaggt cttttggatg
     1021 taatagggac aatatttaca cctgtaatga gtatctttgg acttccaggt gttgcagcaa
     1081 cagctataat gacaatattt atatcaatgg gaggagcatc tggagtaatc gcaggtttat
     1141 ttacagcagg tcaaataagt caagcacatg ttgcaattct attgccaatg ttattgcttt
     1201 caggagcgca gatacaattt atggggagac ttttaggaac agctgagtta aaaactaaat
     1261 attatccaca tatgtttgtt atagcaactt taaatggttg tattgcaatg cttataatga
     1321 attatttcgt agtataggta attataataa agatttaata taaatggaaa gtttaaattt
     1381 taaggaggag ctagattatg gaaactaaca aagactatat tgagtatgta cataaagtgt
     1441 atgattatct acacactata ccagaaaaag gatttgaaga atataagaca tcagagtttg
     1501 ttttaaaaga gcttgaaaaa atggggtttg aaaatattaa taaaggaatt gcaggaactg
     1561 gtattatagt aactatagat tctaaaaaag aaggaccagt atttgctata agagcagata
     1621 tggatgcatt ggaatttatc atagatggag aaaagaaaat gatacatgct tgtggtcatg
     1681 atggtcatac ttctatgctt ttaacagctg caaagttaat aaaagagaga aatttagtaa
     1741 aaagaggtaa gttaaaaata ctttttcaac caggtgaaga aaaattatat ggagcattaa
     1801 gagtaattga ttctggtttg ttggatgatg tagaagaaat ggtagggatg catttaagac
     1861 ctggacaaga ttgtaggttg ggaaaggcga tacctgcaat gtaccattgt gctagctgta
     1921 taatggaatt tacgattaaa ggtatcactt gtcatggttc taaaccacat ttaggagtaa
     1981 atgcagtaga tgctgtctgt ttagcagtga atgcaataaa tgcaataaga gtaaatccag
     2041 ctataccaaa ttctataaaa gtaacaaata tatcagttaa gggagaaact tataataata
     2101 taccagatga agcatttatg gctttagata taagggcaga aagtaatgat ataatagaag
     2161 aattaaaaga aaaagcaata catgctgtaa aaactgctgt aagttctata aatgcagaag
     2221 ctgtactaat ttccaaagat ggagtaccag cagcagaatt tgatgaagaa cttgtaaact
     2281 tggctgaaga aactataaaa gatgtattgg gagctgatgc atctataggt atatttaaaa
     2341 attctggtgg agaagatttc cattattata cacaaaaact aaaatgtaaa actacatata
     2401 ttggattagg agctgatgct acaccaggat ttcataatcc aaatgtaaca tttgatacga
     2461 aagctttaga atatggtgta gatatatggt gtagattggt tgaaaagaga ttgggataac
     2521 atccaaacta ataattctac atttaaaatt ataattatag aagttataga aaaagattgc
     2581 ttatgttaat tagaaaataa ttaatatgag caatcttatt ttgatataat gaaactgatt
     2641 ttggaatatt gaaaaaatat gatgggaaag taattatatt ttaaatctat tggacaaaaa
     2701 agtgatatta ttataatatt aagaattgta aaataatacc aaagtgcatc tagtaataga
     2761 cttaacaatt ataaaaattt tattcttagg agggaaaaaa tgagtaagta taattttgac
     2821 agagtaatag atagagtagg aacagattgt gtaaaatggg attttagaac taattgttca
     2881 acaaaagcac aaaaagatgg tttgcctttt tggattgctg atatggattt tgaatgtgca
     2941 gaaccaataa tagaagcatt acgtaaaaaa gttgaacata aaatatttgg atatagttca
     3001 aatgatagtg ataaatactt taatgcagtt tgtgattggt ataaaaggag atttaactgg
     3061 gaaataaata gaaaagatat tatttttagt cctggtgttg tacctgctgt tgctatttta
     3121 gtaagaatat taactaattc taatgaaggt gtaatagtcc aaaaaccagt gtattaccca
     3181 tttgaagcta agataaagag caataatagg gatgttgtaa acaatcctct gatatatgag
     3241 aatggtactt ataggatgga ttatgatgat ttagaagaaa aagctaagtg tagcaacaat
     3301 aaagtactga tactttgtag tcctcacaac cctgttggaa gagtttggag agaagatgaa
     3361 ttaaaaaagg ttgtagaaat atgtaaaaaa tatgacctat ggataatagc tgatgagata
     3421 cattctgatt taattagaaa aggatttaaa catactcctt tacagtcatt atgcccagag
     3481 tacaaggata aaatagttac atgtatagct ccaagtaaaa catttaatct ggcaggaatg
     3541 cagttgtcta atataatagt gaataatgat gaactaaaaa agaaatatca agaagaggtt
     3601 acagctgttg gagttgcaac ttcaccaaat ccctttgcta ttgtagctac aatagcagca
     3661 tataatgaaa gtgaagactg gcttaatgaa ttaaatgatt acttagataa taatatacaa
     3721 tttattgatg aatacttaaa agaaaaccta ccaaaagtaa aacttgttta tccagaagga
     3781 acatatctag catggttaga ttttactgct tatggattaa atgaagtaga acttgaggat
     3841 ttaatgttta aaaaagctaa tgtattattt gatgaaggtt atatatttgg aaaagaagga
     3901 ataggatttg aaagaataaa tgtagcttgt ccacagtctt tattaaaaga atgtatggac
     3961 agattaaaga ctatatttga aaatttataa agtataggta aaaatttata aagtgtttaa
     4021 aaacaaaaaa ataataaact tgacaaattt taactaatca cttatcatac tattatgaat
     4081 aaatagaaaa cataagagag ctaaatttta ttgaattaaa ctcttaaaga ctttgaaagg
     4141 aagagtagtt atagaatgta attaaagcga gttggtgatg gtgtgagacc aatatgaagt
     4201 ctataatgaa gaacatcctg gagttgctaa ccgaaatttt aaaagagtag gcttagtcgg
     4261 aaccaaaccg ttatcatatt ggggtgtatc gagtaatatc tgtacattgt gagctgggtt
     4321 tgaatttatt tcaaactaat cagggtggta ccgcggaaaa gcaacctttc gtccctttta
     4381 tatagggatg aagggttttt ttaatggaaa aatatataaa tatagggagt gaatgatatg
     4441 agcacaataa taccaaagga ttataaaagt agtttgaacg taattgatac acaaatagct
     4501 ataaaaaaat taaaagattt ttttgaaatg agactaagta atgaattaaa tcttataaga
     4561 gtttcttctc cgttatttgt attgccagaa acaggtgcaa atgataattt aaatggagaa
     4621 aaggctgtaa gctttgatat accatttatg aataaaaatg cagaaattgt tcaatcactt
     4681 gcaaaatgga aaagattagc ccttaaaaaa tatgggtttg aagttggtag tggtttatat
     4741 acagatatga atgcaataag aaaaaatgaa gaattagaca atatacattc tctttatgta
     4801 gaccaatggg attgggaatt ggttatagat aaaagtagta gaaatgaaaa gactctaaaa
     4861 gatgttgtaa aaagattgta tggagtattt aaagatactg aaatttttgt atgtagtatg
     4921 tatgaaggta taaaagaaat attaccagaa gaaataactt ttataacatc acaagagtta
     4981 gaagatatgt atccagaatt atcaccaaag gaaagagaag ataaaattgt aaaagagaag
     5041 aaagcagtat ttataactca aataggaaaa acattaatat caggagaaaa acatgatgga
     5101 agaagtcctg attatgatga ttgggaattg aatggggata tattatttta caatcctgtt
     5161 ttagattcag cattagaatt atcttcaatg ggaattagag ttgatgaaga atctcttgat
     5221 agacaattga aacttgctgg atgtgaagag agaaaagagt ttgactatca taagatgctt
     5281 ttaaatggcg aacttccgta tacaattggt ggaggaattg gtcagtcaag aatatgtatg
     5341 tatttcttac aaaaagctca tataggagaa gtacaagttg gagtatggcc acaggatatg
     5401 attcaaaatt gtagtagtgc aggaattgaa ttattataat ttaaatataa actaattgat
     5461 aaaatttata tctaatatgt tcatcaaatt aattatatcg gttataatgt agaataacct
     5521 ataattataa gaggtgataa atatggagtt tttaaaaata atcattaata tagttttaga
     5581 tattttaaaa aaaattttgg tcagatttaa aaatgctaaa tttggtttgg tttttgtatt
     5641 tgatttactt aaactacctg attttatgac agataaaaga atcaatatag ttgataaaat
     5701 aaaggtaatt tctgtattaa tttttactat atcctacttt gtatctgggg ttgatataat
     5761 tccagagatg attgcagggg catttggttt tatagatgat gctatagttt taatttggag
     5821 tataggtata gtgaatgaag aaattaataa gtatagagtt atcacaaaaa aagataaaca
     5881 ttcaaatata attgaaaatg tagaattttc tataaaagat gaagaagaat aacaatttat
     5941 atatgttatt ctttttttta ttaacaaaaa atggttaaat tgttgacgga gaggtaaaac
     6001 tctattatca taataagtgg atatccaata tttaactaag tattcaatgt gcaagaatgc
     6061 ttaatttaaa aaagttatgg agggtaaata ttatgaagaa aaaaataggt ttagtgccca
     6121 aactaatcat cggtatcata gtcggtattt taatcggaag ttatgcacca gaaataatag
     6181 tacaaatatt agtaacagtt agtactttat tctcagcatt cctaaaattt gttataccat
     6241 ttataattat aggttttgta acagcaggta tagctgattt agcaacaggt gcaggaaagt
     6301 tattggggat aactacggga atagcatatg gttctacctt aatagcagga ttattatcat
     6361 ttgcagtatc tacattaatc ttcccaaatt ttattgatgc aagtgttgca agtcaaattg
     6421 gagacccaga ggcaggaatg ttagctccaa tattcacaat tccattagag cctatggtag
     6481 atgtaacagc tgcaatcgta tttgcatttg taatgggact tggaatatca gctttaagaa
     6541 atcatggaaa aggagagact ttatttaatt tcttccaaga atttcaagga atcgtaacga
     6601 aaacgttgtc aacagtgatt atacctttat tacctttata catagcagga acttttgcaa
     6661 atataactat agcaggggaa gtatggacaa tattaggggt attctggaaa gtatacttag
     6721 tagtaatacc tttacatttt gtatatatgg catgtcaatt cacagcagca ggtgtatttt
     6781 caggaaaaaa tccagtaaga atgttaaaaa atcaagtacc tggatattta acagctatag
     6841 gaactcaatc ttcagcagca actataccag ttaatgttgg ttgtgcagaa aaaaatggag
     6901 taagtaagca aataagagaa tttgttgtac ctctttgtgc aacaatacat ttatcaggta
     6961 gtatgatatc aataacagga tttacaactg cagttttaat gatgaatggt atgccacatg
     7021 gaataggtgt attattccct tatattgcaa tgttaggtat agcaatggtt gcagcaccag
     7081 gagcaccagg tggggctata atgagtgcac ttcctttcct accaatggtt ggaataccat
     7141 cagatggtgg gcttgcaagt ttaatgatag ctttatactt aactcaagac agttttggta
     7201 cagcatgtaa tgtatcagga gataatgcaa tagcagtagt agtagataaa ataaatgatg
     7261 gaatgagtaa aaaaggaaac aaagaagagc aaagtgctta gttttttaat aatcaaaaat
     7321 gagttatctc aaatagagat agctcatttt ttatggtata aaaaattata aaataaagtg
     7381 atttttttat ttaaaaattg ctttaagaga tgatattaat aatttatttt cattaggttt
     7441 taatatacat actctaaaga aatactcatc tagaccttca aatgaacaac aatctcttat
     7501 tattattttt tgtgggagca gttgctctcg aagagattta gcagtcaatt cctttgtctt
     7561 gattttacac aatatgaaat tacctttagt attgtatata tctaagcttt ttatattctt
     7621 aagctcttta agcaggtaat ctctttcagt gttcattaag gaaatagtat ttgatataaa
     7681 atctaaatca ctaaacatga tttcacccat tttagaagct attatgttta tattccataa
     7741 atctagattt ttatttattt catttttgac attagtgtta gatataagac catatccaag
     7801 ccttattcca ggcgttgaaa aaaattttga tgtacctctt ataacgaata aattagaata
     7861 atcatcaact aattgagtac aagagtatgt atctgtatca gtaaactcta cataagtctc
     7921 atcaatcatt aaaaatgagt ctgtattttt taaaatttct ctcacttcta ctttagtaaa
     7981 tgcaaatcca gttggattac taggattaca gattactacc aaatcataat ctttagcatt
     8041 gatagttttt ataagatttt ctaaatttat atgaaaatta tcttcttctt ttgcaaagta
     8101 tttttctata gaacaattaa ttttagataa ctctttttca tactctgaat aggctggaga
     8161 gagtaaaaga gcttgtttag gattaattgt atgtataaat gatgaaatta gttctgtagc
     8221 tccactgcca agtactatat tatctataga acatttgcag taattggata tagaagtttt
     8281 taagtctatg taatcagggt caggatacat agataccata tctatattgt ttacaatgta
     8341 ttgtttggct aaacttgatg taccaaaagg atttatattt gagctaaaat ccataaattc
     8401 ttcctttgaa aagccatact tactagataa actatataaa ttagctccat ggtttgtgct
     8461 cataaaagta cctccaaaaa taaaattata taatcgataa aaataactga ttaatatatg
     8521 tacatataga ttataataca aaggaatcgt tattccaaat ttttaatgta aaaagcaaaa
     8581 aagtatggat aagctgttaa tttaggttta aaaatgatga aaaagatttt aattgatatt
     8641 ttggtatgct ataatatata agttaataga aggaaagcgg gaggatacaa aatgtacaaa
     8701 gttacaggaa aaatgttgac agaagaacaa ataaaagaaa aagtttatga attaggaaaa
     8761 aagatagaag aagactttaa aggcgaagat ttactagtgg taggtatact taaaggagct
     8821 agtgtatttg tttcagattt aataagatgt atagatttgg atgtaaatat agattttatg
     8881 agtgttacaa gttatggaaa ctcaacagag tcttctggaa cagttaaaat attaaaagat
     8941 ttagatgtag atattgaagg aaagaatgtg ttgattgtag aggatataat agattctggt
     9001 ttaacattaa gtaatctagt tgcagcttta aaaactagaa atccaaaatc tttaaaacta
     9061 tgtactctac ttgacaaacc tcagagaaga aaagctaata tacctgtaga ctatgttgga
     9121 tttgttatag aagacaaatt tattgttggt tatggaatag actatgctga aaagtataga
     9181 aatttacctt atataggtat agttgaggat gtagaataga tttaaatgtg aatcaaaagc
     9241 actaatttct aagggagtta gtgcttttta gttaattata taaaatttta gtaaaggaga
     9301 catctatatg gatattcagt taaatatatt attatttttc caaaatttaa gaaatccaat
     9361 tttgaacttt atatttcttg tctttacaat aagcacagaa gcaccgttat taatattaat
     9421 tacaacaatt atatactggt gtataaataa aaaatgtgga cagaaaatac tgtttgctat
     9481 aattggaaat tttgttgtaa atttaggcat caaagagttt gtaaaagctc ccagaccaat
     9541 aggaataaaa ggtcttgaat cattgagagt ttctactgct ggtggttatt cttttccaag
     9601 tgctcatact caaactgcaa caacattttg ggttagtatt atgactatat ttaaaaagag
     9661 atatcttcat ttaatagctg cagttatggt tttaggagta ggattgtcta ggctgtattt
     9721 agctgttcat tggccaatag atgtgatagc gggttggata ttaggaatat tttttacagt
     9781 tgtatttgta aaaatatttg actatattga tgataataaa aattatattt tacttgtagt
     9841 tttacttata ccatttataa tagtggctat atttctaaat agccctgaat attttgaaaa
     9901 atttggtata atagtaggat ttgtatttgg atatatggtt gaggatagat ttgttaaatt
     9961 taatacagat aataataaca aaaaaataaa ttttagtaat aaaaataagg ggagtaaaaa
    10021 tataattttt tcaagaatat gtaggttttt ggttgggata gtaacaatag gaatgttata
    10081 tattggcatt aagttgttta tttcaatgtt aatagtcact ttaaatatga gtgactctac
    10141 tatgagtata atttttatga attttattaa gaatacagta gttgtttttt atggaatagc
    10201 aggagctcca gcattattta aacttttaaa attaaattga ttttaaggta tagagtcaat
    10261 agtttaaatt aaaaaaatta agggtagaaa agagtgatta tttgaagaag gtagtaataa
    10321 taggtggtgg accagcaggg atgatagccg catcaactgc atgtgagaaa ggctatgatg
    10381 taacattaat tgagaaaaat cataaattag gaaaaaaact tgcaataaca ggaaaaggta
    10441 gatgtaatat tactaacgct tgtgaaatag aggaattaat agaaaatgta cctacaaatg
    10501 gaaaatttct ttatagtgct ttttatactt ttacaaatga tgatgtaata agtatgttta
    10561 ataatcttgg agtaaagact aaaacagaaa gaggaaaaag ggtttttcca gagagtgata
    10621 aagcatttga tattgtaaat gctcttgaaa gacaacttaa aagtaagaaa gtaaatatat
    10681 tattaaattc gaaagtagaa aaaataatat ctaaaaataa taaaattgaa aaagtaattt
    10741 taaacgataa aaaagaaatt aagtgtgatt cagttgtagt agcaactggt ggattaagtt
    10801 atccacttac tggttctact ggtgatggat ataaatttgc aatttcacag gggcacacaa
    10861 ttatagatac aaaaccatct ttaattggta tagaagtaca agaaagtttt acaaaagatt
    10921 tagaaaaatt atcattgaga aatgttgaaa taagggtgtt taatagcaaa caaaagaaag
    10981 tttatagtga ttttggagaa cttgaattta ctagatttgg tttagatgga cctataatca
    11041 agtctgcaag ttgtagaatg aaagatacaa ggaaagaaaa ttacactata ttattagatt
    11101 taaaacctgc attagatgag gaaaaattgg ataaaagagt tcaaaaagat tttcagaagt
    11161 atacaaataa aaaatttgaa aaagcattag atgatttact tccaaaaaaa ctaataccta
    11221 taataataaa cttaagtgaa attaatccaa atacggttgt tcaccaaatt tctagagagc
    11281 agagaaaaaa cttagtccat ttattaaaaa atttaaagtt tacagtaaag agatacagac
    11341 ctattgaaga agctataata acttctggtg gtgtaaaagt aaacgaaata aattcaagta
    11401 caatggaatc aaaattagta gaaggtttat tttttgctgg agaagtaata gatatagatg
    11461 catatacagg tggattcaat ttgcaaatag ctttttctac tggatatttg gcaggtttta
    11521 attgctaaaa attacctgaa ttaaaaatgt ttaaaatcac ataatattat cagcaacaca
    11581 aaataaatta aacagaagga aggtaatcaa catggcaagt aacaataaca acaacagaac
    11641 agtagtacca ggagcaaaag aggctttaaa ccaaatgaaa ttagaaatag ctaatgaact
    11701 tggtatgagt aattatcaac aagttgataa aggaaacctt actgcaagag aaaatggtta
    11761 tgtaggtgga tacatgacta aaaaattagt tgaaatggct gaacaacaaa tggctggaaa
    11821 aagcaacaga tagttataaa taattattta taactattgg ctattagttt agctagagct
    11881 atctcaaata tagaaagtaa tttctaaatt gagatagctt ttttttatta aattattaaa
    11941 tagatatatt tttatgtaat aaattttatg tatttggata aaataataca aatgaatatg
    12001 ttacataagg agtgatgtaa aatgagtagt gtaaattttg aggatttaaa aaacaaattt
    12061 attaatagtg acttagatga aaaaataaga atatatacaa caacagaagg tttatcagta
    12121 gaacaattta aagagctact aaaatattat ccaatacaac atttatctaa actagaaaaa
    12181 gcacttggat agcagtattt aatccaaaat taaaaaggca atttatttaa tattaaaaat
    12241 attttttatt aaataaattg cctttttata ataggtttaa attattatgc ttttgatata
    12301 taattataga ttctctcatt tccaagttca atagacccag tattaataag agtaactatt
    12361 ccttctatat ctctagcagt taagtattta tatggaatta ataaattata accagtatta
    12421 cttagtaagt tttttaattg ggttatttga gagatattga aacattttgc agttttagta
    12481 gatttttttc ttaagttaga taaattttca ttttgaatat ttattaaagt ttctatatag
    12541 tttctataag atatcttaaa gtttgtctca ttgactattt tttcattaag tatactactg
    12601 ataaaatctt gagacaatat attatctgca aatttatctg ctgttaattt tccagatgtt
    12661 atgccttttt gatattttct aagaattttt ttagtatagc agtatatttt atttctcgtt
    12721 tctaaatcga gttgttctat ttgcacaaaa ccacttcctt ctaattataa aaatatttat
    12781 taaaaatcta tacttaacta ataaagcttc aataacttat ttacaataaa tactaaatca
    12841 taaaatattt gttatttttt attattacca agtataaaaa atattataat tgtaaaactt
    12901 acaaatatat gtaaaatatt taggagtgat gaaaatgtta aatgggataa taaagctttt
    12961 ttattctgaa attgtaaaaa caaagattaa taacttagat tcaagtggat attctttaag
    13021 agatgaatgt aaagaaatca gaaatataac tctaaagata gatagtgtat tttttaagct
    13081 tttaaagtta gcttttggtt caatattgct tatggtagct tttaatttaa acatggtttt
    13141 aggtatagga gtgtttttag ttggtgtagt ttatatacta tataaaagaa atatggaaga
    13201 acaagtaaaa gagcatataa ataatgtgaa aaataatatc gacatctcta aaataacttt
    13261 tatggatgaa aaagggagaa caggtctaaa tgcattaatt acattacttc ttataggatt
    13321 attgacagga tttaactgga tattagttgc tagttttgtc gttgtttttg tttttactat
    13381 aaagaatgta tgttaaaata ctaataaata gtttaatata tagggggaga aattgagtat
    13441 gactaatggc agttataaaa tgaagaattt agtggaaata tccgctatgg tgactgaatc
    13501 tacagatttt tttaatataa aagatgacat aatagaaaaa atgttagaag ttgttcaccc
    13561 tacaaaggca tgtgtgaatc tattttataa aaatgattct aaatatgcct acttagtatg
    13621 ttcgcaaacc ttagaatatg tacctcaaat ttttccaata aatagtctta aaggtgcaaa
    13681 aattgatttt gacacatatc cagagtatat acatgaggct gtaaatgaaa aaaagataat
    13741 atatgtggaa aatgtatttg aagattctag agcagaaggt gaacgagatt tagcaaaagc
    13801 tgaaggttat attgggagaa tagtttttcc ttttataata aataacgtag ttgttggatt
    13861 tatgacttgt tttttaaaag aggatgatta tataacagaa caagatatag attttatatc
    13921 atctgttgca tcactcttaa gtttatcaat agaaataact aataaaaata ataatgtaca
    13981 aattttaatt gataaactaa gaggctcaat aagtgccata aatgaagcta ctaaaaaact
    14041 ataccttaat aagagtattg atggattttt ggaaaattta agtaaacaag cgtgtaatat
    14101 tactaatagt aaagaagctt taataattat aaatagtcat cataataagg atgctatagt
    14161 tagttgttat aatgttgagc aaaaaaagaa aacaaattta tatcctatga ttgatatgtt
    14221 tttaaagaaa gagtcattgg gggggtattt aaataattta aaaccatgct caaaaaaggg
    14281 aataaatttg gaaagttata tatattacaa acttcaggat aaaaatgata ctataggatg
    14341 tatagtttgt gcaaatagca aaaactatac tagtgatgat ttaaatattc ttagtatatt
    14401 gtccaaacaa gtttctgttg gtatgcaatt atatgaacat aatgaaaagg aagtaaaaca
    14461 caaagttctt gaaaatgagt tgaacatatt aaataaacaa caacagctta ttatggataa
    14521 aggtaaaatg gattgtaatg atgagaaaga actttatttt taccataaac cagcaagggt
    14581 agtaggtgga gatttttatt atgctacaaa agtggatgac gaacatatag tttatattgt
    14641 tgctgatgta atgggacatg gaatggtatc aaattatgtt gttgcaatga taaaaggtgc
    14701 ttttaaagta ttatgcaatc aatacaatac accaagagaa ataatgacaa atttaaatag
    14761 gatgttatat gatgaatttg acaagatggg agtatttaca acttgtttga taggtattat
    14821 agatactaaa gaaaatatga ttactgtgtc taatgcaggt cactatagtc ctgtagttgt
    14881 aaagaaagat ggcacaatag aaaataattt aaattgtaaa aagggcatac ctattggaat
    14941 aatggaagat gctacttatg aaaataatac tctttcaatg gaagattatg caatggtatg
    15001 tatgtacact gatggaattt tagagataaa aaattcatca aaagaagagt atggtataaa
    15061 ccgattagaa aactttctaa aagaaaattt tagattaaat caacagttaa tagtagaaaa
    15121 tctaaaattg gatttaaaga acttctcatc aaaagataat tatgatgatg atattttaat
    15181 agttatgtta aaggataggt agattgatta tggattcaaa cgataaaaaa ggacttaaaa
    15241 gtccagagat tataataata aatggaagtc caagaattaa taaaaattgc agttttatag
    15301 caaatgaagt aaaagctatg ctagaagagt gtggattaag ttgtaaaata tttaatatct
    15361 acaatatgga tattgaatat tgcacagcat gtggattttg tgaaaaaaca gggtattgca
    15421 agtttaatga tgatatgaag ccattatata aaatgtttga tgattcaaaa ggaactatag
    15481 taataagtcc tgtacatttt gattcaatat cagctaaatt aaagactgtt gttgatagaa
    15541 ctcaagctat atatgcaagt aaatatgtat taaataaacc ttcaattgat agaagtaaga
    15601 aacggatagg aatgtatatt gcagtgggag ggagtaaatc atatgattca cagtttaaag
    15661 gtggacagat tgttatggat tttttcttta agagtataaa tactaaactt ttacacaata
    15721 tatatttaaa caatacagat gatgtatctt atatagataa tcaagaattt aaagatataa
    15781 tatataaaaa tttaaagata tatattgatt caatataatt tgattttgta ggtaatatta
    15841 tgtataattg tattgcaata atttaaataa ttaaaaggag ggaatttcaa tgaaattacc
    15901 aatagcatta tctaataaac atgttcattt gagtcaagct gatatagacg tattatttgg
    15961 agcaggtcat gagttaacta aatttaaacc attatctcaa ccagggcaat atgcctgtga
    16021 agaaaaagtg gatttagtag gaccaaaagg aactttaaaa ggagttagag tactaggacc
    16081 agctagagct catactcaag ttgaaatatc tttagcagat ggtttcccat taggagtaaa
    16141 agcaccaata aaagaatctg gtgatatagc tggaactcca ggtgttaaat tagtaggacc
    16201 tgctggagaa gttgaaatga aagaaggagt tatagttgct tctagacata tacatatgag
    16261 caatgaagat gctgctaaat ttggtgtaac tgataagcaa atagtaaaag ttaaaacatc
    16321 tggaccaaga gcattagtat ttgaaaatgt attagtaaga gctagtgaca gctttaatct
    16381 agaaatgcat gttgatatgg aagaaggaaa tgcagcaggc gttaaaaatg gagatttagt
    16441 agaattaata gttgattaat attataaata gactttatgc tagtagatat tttatttgct
    16501 agcatatttt taaatgtaat aaatttctat aggataaatt taatcgatta gattaattta
    16561 taaaataaag gggtattata aaaaatgtaa taaaaactta caaaaatatg atgtaatatg
    16621 gtaaaat
//
LOCUS       DAMJXI010000077        16619 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.081, whole genome shotgun sequence.
ACCESSION   DAMJXI010000077 DAMJXI010000000
VERSION     DAMJXI010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16619
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.081"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(75..2141)
                     /gene="fusA"
                     /locus_tag="PC465_003151"
     CDS             complement(75..2141)
                     /gene="fusA"
                     /locus_tag="PC465_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDF2650432.1"
                     /translation="MARKFPLERTRNIGIMAHIDAGKTTTTERILFYTGQTHKIGETH
                     EGASQMDWMEQEKERGITITSAATTASWKDHRINIIDTPGHVDFTVEVERSLRVLDGS
                     VAVFCAKGGVEPQSENVWRQAETYGVPRIAFVNKMDILGADFYNVVSMMKSRLNSNAV
                     PMQLPIGKEDSFIGIIDLLKMDAVIYKDDLGVEMEETDIPEDMKELAAEWREKLVESV
                     AETDEELMMKYLEGEELTIDELKVAIRKATIACEMNPVFCGTAYRNKGVQLVIDAVLD
                     YLPAPTDIPAIKGILADGEEAERHSSDEEPFSALAFKIMTDPFVGKLAFFRVYSGTLE
                     SGSYVLNATKNKRERIGRILQMHANTREEITKVYAGDIAAAVGLKDTTTGDTLCDPAN
                     PIILESMEFPEPVISVAIEPSSKAAQEKMGIALQKLAEEDPTFTVKTDQETGQTIISG
                     MGELHLEIIVDRLLREFKVEAKVGAPQVAYRETITQPVDVEYKYSKQSGGRGQYGHVK
                     IRVAPQEPGEGYKFTNKTVGGSVPKEYVGPVDMGIQGAMQSGIVAGYPVVDVAVELYD
                     GSYHEVDSSEMAFKMAGSMAFKDAMKKGNAVLLEPYFKVEVVTPEDYMGDVMGDLNSR
                     RGLIQGMEARSGAQVINAFVPLSEMFGYSTDLRSSTQGRATYTMIFDHYEQVPASVAK
                     KIAEGK"
     gene            complement(2190..2660)
                     /gene="rpsG"
                     /locus_tag="PC465_003152"
     CDS             complement(2190..2660)
                     /gene="rpsG"
                     /locus_tag="PC465_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HDF2650433.1"
                     /translation="MPRKGNIPKREVLPDPMYGSKVVTKLINNLMVDGKKGKSQRIVY
                     DAFAIVAEKTGEEALEVFNKAMDNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLR
                     WLVKYTRARGEKGMVEKLAKEIMDAANNTGASVKKKEDTHKMAEANKAFAHYRW"
     gene            complement(2784..3206)
                     /gene="rpsL"
                     /locus_tag="PC465_003153"
     CDS             complement(2784..3206)
                     /gene="rpsL"
                     /locus_tag="PC465_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HDF2650434.1"
                     /translation="MPTINQLVRKSRKALEKKSTAPALQKGYNSLNKKVTDASAPQKR
                     GVCTSVKTVTPKKPNSALRKVARVRLTNGIEVSAYIPGEGHNLQEHSVVLIRGGRVKD
                     LPGVRYHILRGTLDTAGVDKRRQSRSKYGAKRPKEAKK"
     gene            complement(3495..6980)
                     /gene="rpoC"
                     /locus_tag="PC465_003154"
     CDS             complement(3495..6980)
                     /gene="rpoC"
                     /locus_tag="PC465_003154"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HDF2650435.1"
                     /translation="MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKD
                     GLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPMS
                     HIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALE
                     KYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKK
                     SGNKPEWMILDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGA
                     PDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEK
                     VKPEVWDVLEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADF
                     DGDQMAVHVPLSVEAQAEARFLMLSVNNILAPKDGSPITTPSQDMVLGCYYLTIEAQD
                     GAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFIFNENIP
                     QDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKALGFKYST
                     LGGITVAVDDMSVPEEKKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTD
                     KVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMRGLMANASGKTVEIPVKSNFR
                     EGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREIDCGTEDTTEI
                     YAIKEGNEVIEEIYDRIVGRYTIDPILNPETGEVIVEADSMIQEDEAETIVALGIEKI
                     RIRTVLNCKTNHGVCSKCYGRNLATGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTG
                     GVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKEVNVIPEEGETQT
                     YVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQG
                     VDVNDKHIEVIVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAK
                     RVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVILGKLIPAGT
                     GMKKYRNIAVEKIED"
     gene            complement(7022..10738)
                     /gene="rpoB"
                     /locus_tag="PC465_003155"
     CDS             complement(7022..10738)
                     /gene="rpoB"
                     /locus_tag="PC465_003155"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HDF2650436.1"
                     /translation="MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLK
                     EVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKET
                     GEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
                     VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSA
                     TLEKDNTKTVEEGLVEIYKKLRPGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNK
                     KLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKK
                     VRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELI
                     PKHILLDDIIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERV
                     IKERMTVQDMEAITPQALVNIRPVSAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA
                     LGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEFGFIESP
                     YRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMV
                     PESRVDYMDISPKQVVSVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTG
                     IEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNRDRYNLLKFKRSNSGTCINQT
                     PIINKGDQIIKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKED
                     RLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILV
                     GKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGIIVDVKVFTRENGDDL
                     SPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFMENGTPLDIILNP
                     QGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTL
                     YDGRTGESFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPESFKVLIK
                     ELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEIEDDF
                     AENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM"
     gene            complement(11209..11997)
                     /locus_tag="PC465_003156"
     CDS             complement(11209..11997)
                     /locus_tag="PC465_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDF2650437.1"
                     /translation="MEKLQGKIAVVTAATKGIGLASAEILAKNGATVYLAARSEELAN
                     EVINKISAEGGCAKFVYFNAREEETFTSMIEEVVKKEGKIDILVNNFGSTNPSLDKDL
                     VTGDTDNFFDTVNTNLKSVYLPCKAAIPHMIKNGKGSIVNISSIGSVLPDLSRIAYCV
                     SKAAINSLTQNIATQYAKDNVRCNAVLPGLIATKAALDNMSPEFIKEFLKHVPLNRIG
                     EPDDIAKAVLFYASDDSSFITGDLLEVAGGFGLPTPQFADNILG"
     gene            complement(12388..12753)
                     /gene="rplL"
                     /locus_tag="PC465_003157"
     CDS             complement(12388..12753)
                     /gene="rplL"
                     /locus_tag="PC465_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HDF2650438.1"
                     /translation="MTIEQILEAIENMKVLELNELVKAAEEKFGVSASAPVMVAGAAA
                     GGPAAEEKTEFDVVLTDVGSSKVGVIKAVREITGLGLKEAKEVVDNAPKTVKEGASKE
                     EADQIKEKLEAAGAKVEVK"
     gene            complement(12811..13317)
                     /locus_tag="PC465_003158"
     CDS             complement(12811..13317)
                     /locus_tag="PC465_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HDF2650439.1"
                     /translation="MRKAIEIKSEVVSEIVEKLQKSSAAVVVDYKGLTVEEVTELRKQ
                     MREAGVDYKVYKNTLVRRAAKEVGIEQFNDELLVGTNAIAFGYDDPVAPARILKGFMD
                     SHPKMKLKMGIVEGAFYDESKIVEMANIPSREVLIAKLLGSLKAPVSNFAYLIDAIAK
                     KAEGQEEA"
     misc_feature    complement(13360..13488)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(13540..14238)
                     /gene="rplA"
                     /locus_tag="PC465_003159"
     CDS             complement(13540..14238)
                     /gene="rplA"
                     /locus_tag="PC465_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HDF2650440.1"
                     /translation="MAKKGKRYAGALEKVDRTKFYDASEALTLVSDIAGAKFDETVEA
                     HIKLGVDSRHADQQVRGAVVLPHGTGKTKRVLVFAKGEKAKEAEQAGADFVGAEELVQ
                     KIQGENWFDFDIVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVAKAIDEIKAG
                     KVEYRLDKTNIIHVPVGKVSFGGEKLTENFTALMDAIIKAKPAAAKGQYLRSITVASS
                     MGPGVKINPARTAE"
     gene            complement(14309..14734)
                     /gene="rplK"
                     /locus_tag="PC465_003160"
     CDS             complement(14309..14734)
                     /gene="rplK"
                     /locus_tag="PC465_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HDF2650441.1"
                     /translation="MAKKVIGQIKLQIPAGKATPAPPVGPALGQHGVNIMGFTKEFNA
                     KTADQAGMIIPVVITVYQDRSFSFITKTPPAAVLIKKALNLKSGSGEPNKKKVAKMTS
                     AQVREIAELKMPDLNAASVEAAMSMIAGTARSMGVVIED"
     gene            complement(14773..15315)
                     /gene="nusG"
                     /locus_tag="PC465_003161"
     CDS             complement(14773..15315)
                     /gene="nusG"
                     /locus_tag="PC465_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination factor
                     NusG"
                     /protein_id="HDF2650442.1"
                     /translation="MSELQEASWYVVHTYSGHENKVKATIEKAVKTRGMEDCIRQVVV
                     PTEEVVETTKTGKEKTRQRKVYPSYVLVKMIITDESWYVVRNTKGVTGFVGPGSKPVP
                     LSEDEVKAMGIDTTDPKVVNSDIDFEIGDTVKVSQGPFSGQIGNIEEIDLENREVKVC
                     INAFGKRTLFVIELEGIEKI"
     gene            complement(15335..15556)
                     /gene="secE"
                     /locus_tag="PC465_003162"
     CDS             complement(15335..15556)
                     /gene="secE"
                     /locus_tag="PC465_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HDF2650443.1"
                     /translation="MAAQKNDGAKTKKRFSLFGYLKETKQELKRVTWPTKKELFKNTS
                     IVLTVVISCTILVWGIDTILSGALALLLK"
     gene            complement(15582..15731)
                     /gene="rpmG"
                     /locus_tag="PC465_003163"
     CDS             complement(15582..15731)
                     /gene="rpmG"
                     /locus_tag="PC465_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004402360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDF2650444.1"
                     /translation="MRVKVTLACTECKQRNYNTTKNKKNNPDRIELQKYCRFCKKHTT
                     HKETK"
     gene            complement(15981..>16619)
                     /gene="tuf"
                     /locus_tag="PC465_003164"
     CDS             complement(15981..>16619)
                     /gene="tuf"
                     /locus_tag="PC465_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDF2650445.1"
                     /translation="EWGDKIVELFEQIDEYIPAPERDTDKPFLMPVEDVFSITGRGTV
                     ATGRVERGVLKVQDEVELVGLTEAPRKVVVTGVEMFRKLLDQAQAGDNIGALLRGVQR
                     NEIERGQVLAKTGSVKAHTKFTAEVYVLKKEEGGRHTPFFDGYRPQFYFRTTDVTGAC
                     KLPEGIEMVMPGDNVTMEVDLINSIVVEEGLRFSIREGGRTVASGVVATIIE"
BASE COUNT         4617 a         3409 c         2067 g         6526 t
ORIGIN      
        1 atcttgtgct agatgagaga tatctctcat ctagctgatt attttttata tttatattat
       61 taattatttt taaattattt tccttcagct attttcttag caactgaagc tggaacttgc
      121 tcatagtgat cgaatatcat tgtgtaagtt gcacgacctt gagttgaaga tcttaggtct
      181 gttgagtatc caaacatttc tgaaagtgga acgaatgcat ttataacttg tgcaccactt
      241 ctagcttcca taccttggat taatcctctt cttgagttta agtcacccat aacatctccc
      301 atgtaatctt ctggagtaac aacttctact ttgaagtaag gctctaaaag aactgcatta
      361 cctttcttca tagcatcttt gaatgccatt gaaccagcca tcttaaacgc catctcagaa
      421 gagtcaacct catggtaaga accatcatat aactcaacag caacgtctac aactggatat
      481 ccagcaacta taccagattg catagctcct tgtataccca tgtcaactgg accaacatat
      541 tcttttggta ctgatccacc aacagttttg tttgtgaatt tgtatccttc acctggctct
      601 tgaggagcaa ctctaatctt aacgtgaccg tattgtcctc taccacctga ttgcttagag
      661 tacttgtatt caacatcaac tggttgagtt atagtctctc tatatgcaac ttgtggtgca
      721 ccaactttag cttctacttt aaattctctt aataatctat ctactattat ctctaagtgt
      781 aattcaccca taccagatat tatagtttgt cctgtttctt ggtcagtctt aactgtgaaa
      841 gttgggtctt cttcagctaa tttttgaaga gctataccca ttttttcttg agctgcttta
      901 gaacttggtt ctatagcaac agatataact ggctcaggga attccataga ttcaagtatt
      961 attggattag cagggtcaca taatgtgtct ccagtagtag tatcttttaa tcctactgct
     1021 gctgctatat ctccagcata cactttagtt atttcttctc ttgtattagc atgcatttgt
     1081 aatatacgac caattctttc tctcttattc ttagttgcat ttaaaacata agaacctgat
     1141 tctaatgttc cagaataaac tctgaagaac gctagttttc caacgaatgg gtcagtcatt
     1201 attttgaatg ctaatgcaga gaatggctct tcatcagaag aatgtctttc agcttcttct
     1261 ccatctgcta atataccttt tatagctggt atatcagttg gcgctggtaa gtaatctaaa
     1321 actgcatcta ttactaactg aacacctttg tttctataag ctgtaccaca gaaaactggg
     1381 ttcatttcac aagctatagt agcttttctt atagcaactt ttaattcatc tatagtaagt
     1441 tcttcacctt caaggtattt catcattaat tcttcatcag tttcagctac tgattcaact
     1501 aatttttctc tccactcagc agctaattct ttcatatctt ctggtatatc tgtttcttcc
     1561 atttcaaccc ctaggtcgtc tttgtatata acagcatcca tttttaataa gtctattata
     1621 cctataaatg aatcttcttt acctattggt aattgcatag gaactgcatt agaatttaat
     1681 ctagatttca tcatgcttac aacattgtag aaatctgcac ctaatatatc cattttattt
     1741 acaaaagcta ttctaggtac tccataagtt tcagcttgtc tccatacatt ttctgattga
     1801 ggctcaaccc caccttttgc acagaataca gcaactgaac cgtcaagaac tcttagagat
     1861 ctttcaacct caactgtgaa gtccacgtgt ccaggagtat ctattatgtt tattctatgg
     1921 tctttccatg aagcagtagt agcggcagaa gttattgtta tacctctttc cttttcttgc
     1981 tccatccagt ccatttgaga agctccttca tgagtttctc ctattttatg agtttgccca
     2041 gtataaaaca ggattctttc tgtagtagta gtttttcctg catctatatg agccatgatt
     2101 cctatattcc tagttctttc caaaggaaac tttctagcca tggttatcct ccttatgata
     2161 tcctcaattt tataagatat ctatatatcc taccatctgt aatgagcaaa tgctttatta
     2221 gcttctgcca ttttatgagt atcttctttt ttcttaactg aagctccagt gttgttagct
     2281 gcgtccatta tctctttagc tagcttttca accattcctt tttctccacg agctctagta
     2341 tattttacta gccatcttaa acctaatgtt tgtcttcttt caggtctaac ttcgattggc
     2401 acttggtagt ttgccccacc aactcttctt gcttttactt ctaaaacagg cattatatta
     2461 tccattgctt tattaaatac ttctaaagct tcttctcctg tcttttcagc aacaattgcg
     2521 aaagcatcat aaactattct ttgagacttt cctttttttc cgtctaccat tagattattt
     2581 attaatttag taactacctt actcccatac ataggatctg gtaaaacttc tctttttgga
     2641 atattacctt ttcttggcat ttcgcttccc tccttaatta tttaacttaa atcataggta
     2701 ctcgacataa atcatttaat gccgtgatgc cgtaaatata tatatattta aagcaccgaa
     2761 ctataatcaa tcattaattg tttttacttt ttagcttctt taggtctctt cgcaccgtat
     2821 ttagatcttg attgtcttct cttatcaaca cctgctgtat ctagagtacc tcttagtata
     2881 tggtatctaa cccctggaag gtcttttact cttcctcctc ttataagaac aacactatgc
     2941 tcttgtaagt tgtgtccttc tcctggtata taagcagaaa cttctatacc attagttaat
     3001 ctaactctgg caacttttct taaagctgag ttaggcttct taggagtaac tgtttttact
     3061 gaagtacaaa cccctctttt ttgtggggca ctagcgtcag ttactttctt atttaaagag
     3121 ttgtaacctt tttgtaatgc tggagcagta gatttcttct ctagcgcttt tctactttta
     3181 cgaactaatt ggttaattgt tggcatcatc tgcacctcct tccaaatttt cgatcttatc
     3241 agtgaccgcc aactacatca atatgaatat tcatactgac tgattgtaac attcgttact
     3301 tacaatttaa tgtctataac acataaatat gtgatattag cacttttcta gcttgatgct
     3361 ttttagttct catttattgc catctaaaag tcactaagaa cttgttcaag cccttagtgt
     3421 acttttaaac aacacacttt actattttaa caccacaaat aatggttgtc aagatttctt
     3481 tactctatat gctattaatc ttcaattttt tcaacagcta tatttctata tttcttcatt
     3541 cctgttcctg ctggtattaa cttacctaat ataacatttt ctttaagtcc tattaagtgg
     3601 tcttctttac cttttattgc tgcctctgtt aatactcttg ttgtttcttg gaaagaagct
     3661 gctgataaga atgaatcagt tgcaagagat gctttagtta taccaagtaa aactctttta
     3721 gcaactgctg gtcttagacc tttatctata gcatctttat tacattcatt gaatgttaat
     3781 acatcttcat atccacctgg caataaatct gtatctcctg ggtcttcaac ttttacttta
     3841 gatagcattt gtcttactat aacttctata tgcttatcat taacatcaac cccttgaagt
     3901 ctatacactc tttgaacttc tttaactata tattcttgaa ctcccttaac accatttact
     3961 cttactatat catgaggatt tataaatcct tgtgttagag ggtctccagc ctctagcatt
     4021 tgaccttgct taacttttaa tctagaacca tatggaatta catatgtttg agtctcgcct
     4081 tcttctggta ttacatttac ttcttttctc tttcctgttt catcaatttc aactctacca
     4141 gatacttcag ttattacagc taatcctttt ggttttctag cttcaaataa ttcttcaacc
     4201 cttggtagac cttgagttat atcagctcct gcaactcctc cagtatggaa tgtacgcatt
     4261 gtaagctgag tacccggctc accgatagat tgagctgcta ttataccaac tgcttcacct
     4321 atattaactt cttttcctgt tgccaagttt ctaccataac acttagaaca aactccatga
     4381 ttagttttac agttaagaac tgttcttatc ctaatttttt caattcctaa agctactata
     4441 gtttctgctt catcttcttg tatcattgaa tcagcctcaa ctataacttc tccagtttca
     4501 ggatttaata tagggtctat agtatatctt cctacaattc tatcatatat ctcttctata
     4561 acttcatttc cttcttttat agcataaatc tctgtagtat cttctgttcc acaatctatt
     4621 tcccttacaa taacatcttg acttacatca acaagtcttc ttgttaaata tccagattca
     4681 gctgtacgta tagctgtatc ggcaagacct tttctggcac catgtgaaga tgtaaagtat
     4741 tctagtactg ataaaccttc acggaaatta gatttaactg gtatctcaac tgttttacca
     4801 gatgcatttg ccataagacc acgcatacct gccagctgtc taatttggtt tttagaacct
     4861 ctggctcctg aatgtgccat tatatatata ttatttaatc tatctagtcc acccataaga
     4921 gcatcagtaa ctttatcagt tgtttctgtc catgtctcta taactttttc atatctttct
     4981 tcatcagaga ttagacctct tctgtatgct ttttcatact tatcaacttt agcttctgcc
     5041 tcagctataa atactttctt ttcttctggg acactcatat catcaacagc aactgttatg
     5101 ccacctaatg tagaatattt aaatcctaga gcttttatat aatctagtaa ttcagctgtt
     5161 tctgtatttc cgtgttttct aaagcattta tctattattt taccaagaga ttttttatct
     5221 gctaagaaat caacttcaag tgcaaatgga ttttcttttc tatctacaaa acctaagtct
     5281 tgaggtatat tttcattaaa tataaatcta ccaacagtac tttcaaccaa tgaacttctt
     5341 ccatcttcaa gtgttacctt aagtttcact aatgcatgta gatgaactga tttattgtaa
     5401 taagcaagta atagttcatt aaagtcttta aataccatac ctgttccttt agctccatct
     5461 tgggcttcta ttgttagata atagcaacct aaaaccatat cctgagatgg agtagttata
     5521 ggtgaaccat ctttaggagc aagtatatta tttacagaaa gcattaagaa tcttgcttct
     5581 gcttgtgctt ctactgataa aggtacatga actgccattt ggtcaccatc aaagtctgca
     5641 ttataagctg tacatacaag aggatgtagt tttatagcct taccttcaac taagattggt
     5701 tcaaatgctt gtatacctaa tctatgtaga gtcggtgcac ggttaagaag aactggatga
     5761 ctttttataa catcttctaa aacatcccaa acttctggct taactttttc tactatagat
     5821 ttcgcacttt ttatattatg tgcataacct tctttaacta atttatccat aacaaatggc
     5881 ttgaataatt ctaatgccat cttctttgga agtccacatt gataaaattt aagttctggt
     5941 ccaacaacta taacagaacg tcctgagtag tcaacacgct taccaagtaa gttttgacgg
     6001 aaacgacctt gcttaccttt taacatatct gataaagatt taagtggtct atttccaggt
     6061 cctgttacag gtctacctct tctaccatta tctatcaatg catcaacagc ttcttgaagc
     6121 attctttttt catttcttac aattatatct ggagctccaa gctctaataa tcttttaagt
     6181 ctattgtttc tatttataac tcttctatat aaatcattta ggtctgaagt cgcaaatctt
     6241 ccaccatcaa gttgtaccat tggtcttaaa tctggtggta ttactggtat tgcatctaaa
     6301 atcatccatt ctggtttatt tccagacttt ttaaatgcct ctacaacttc taatcttctt
     6361 attgttctaa ctttcttctg ccctgtacta tcttttaact ctgctcttag gtctttactt
     6421 tgttgctcta aatctatatt ttgtagtaat gtctttacag cttcagcacc cattcctaca
     6481 gtaaaagtat atccatactt ttcaagagca gttctgtatt ctttttctgt aagcaattgt
     6541 ttttcgttta atccagtctc tcctggatca actaccacat atgaggcaaa gtataatatt
     6601 ttttctaacg atcttggtga catatcaagt aaaagtccca ttctacttgg tatacctttg
     6661 aagtaccaga tgtgagacat aggagcagct agctctatat gtcccattct ctctcttctt
     6721 acttttgatt tagttacttc tactccacat ctatcacaaa ctacaccttt atatctaact
     6781 cttctatatt taccacagtg gcactcccag tctttttgtg gtccaaatat tctttcacag
     6841 aaaagaccat ctttttctgg ttttaaagta cggtaattta tagtttctgg ctttttaact
     6901 tctcccctag accattgtct tattttttct ggagaagcca atgctatttt tatcgactcg
     6961 aaattgttta attcaaacaa ggagttctct cccttctatt tgagatttac attaattaaa
     7021 tttacatatc aaagtcatca ctatcaaaat ctatttcttc ttcaaataaa tcatcttcag
     7081 tgaattcttc taaattctct atatcctcat cttctgcatt ttctgcaaaa tcatcttcaa
     7141 tttcttctat tatattactt tcttcaactt ctcccatatg atttacaaca tctagctcaa
     7201 attcacctat tgtatcatct tcatccacag attctcttac ttctatttct tggtcttcat
     7261 ctgtcaatac ttttacatct aagcataaac tttgaagttc ttttataaga accttaaatg
     7321 attctgggat tcctggttca ggtatatttt cacctttaac tatagcttca tatgttctaa
     7381 cacgacctac aacgtcatca gacttaacag taagtatttc ttgaagtatg tgagcagctc
     7441 catatgcttc cagagcccaa acctccatct ctccaaatct ttgtccacca aattgtgctt
     7501 taccacctag tggctgttga gtaactaatg agtatggtcc agtacttctt gcatgtagtt
     7561 tttcatctac taagtgatgt agtttcaagt agtacatata tccaacagtt attctgttgt
     7621 caaaagactc acctgttcta ccatcatata aagttaattt accatctcta ggatacccag
     7681 cttcttcaag agcatccatt atgtcatact cattagcacc atcgaatact gatgttgcta
     7741 cataccatcc taatgtctta gcagcaagtc ctaaatgaac ttctaaaacc tgaccaatgt
     7801 tcatacgtga tggtatacct tgtgggttaa gtattatgtc tagtggtgtt ccattttcca
     7861 tgaatggcat atcttcttca ggtaatactc ttgatataac ccctttatta ccatgacgac
     7921 cagccatttt atctccaact tttatttttc tctttttagc tatatagcat cttactaatt
     7981 catttactcc tggagataaa tcatctccat tttctctagt aaatactttt acatcaacta
     8041 ttataccaga ttcaccatga ggcactttaa gtgaagtatc tctaacttct ctagcctttt
     8101 ctccaaatat tgcacgaagt aatctttctt cagcagtaag ttcagtttct ccttttggag
     8161 ttactttacc aactaatata tcacctgagt ctacttctgc acctattctt attatacctc
     8221 tgtcatctaa gttcttaatt gcactatctc caacattagg tatatctcta gttatttcct
     8281 ctggccctag ttttgtatct ctagcttcac attcatattc ttctatatga attgttgata
     8341 atctatcttc tttaactaat ctttcattta ttaatatagc atcctcgtag ttataacctt
     8401 cccaagtcat gaatgctata agacagtttc ttccaagtgc aacttctcct aaatcagttg
     8461 ctggaccatc tgctataaca tcacctttta ttatctggtc acccttattt attataggtg
     8521 tttgatttat acaagtacct gagtttgaac gtttaaactt aagtagatta tatctatctc
     8581 tgtttccatc ttctcttttt ataattattt catctgctgt tactctttct gctataccag
     8641 aatttctagc aacaacaact gctccagagt cttttgctgc tctgtattct ataccagttc
     8701 ctataattgg tgcttctctt ctaactagag gcactgcctg acgctgcatg ttcgctccca
     8761 taagggcacg gttggcatca tcattttcta agaaaggtat catagcagtg gcaacagata
     8821 caacctgctt aggagatata tccatgtaat ctactctact ttcaggaacc atttcaacag
     8881 caccatttac agttctacaa acaactctat ggtttacgaa tttaccatct tctgttaatg
     8941 gctcatttgc ctgagctctt acgaataaat cttcttcgtc agcagttaaa taatgtattt
     9001 catcagtaac tgttgatgtt tctttatcaa attttctata tggtgattct ataaatccaa
     9061 attcatttat ttttgcataa gttcctagag agtttataag accgatattt ggtccctctg
     9121 gagtctctat tggacacatt ctaccatagt gtgaatggtg aacgtcacgc acttcgaatc
     9181 cagctctttc tcttgaaaga cctccaggcc caagggctga taatcttctc ttatgcgtta
     9241 actcagatag aggatttgtt tgatccatga actgagataa ctgagaacta ccaaaaaatt
     9301 cttttattgc agctgaaact ggtcttatgt taactaacgc ttgaggcgtt atagcttcca
     9361 tatcttgaac cgtcattctt tcttttataa ctctttccat tcttgaaaga ccaattctaa
     9421 cttgattttg taacaattca cctacagatc ttattcttct gtttcctagg tgatctatat
     9481 catcaatatt tcctatatta tagaatatat tgaactcata acttattgaa gctattatat
     9541 catctaataa tatatgtttt ggtataagtt ctttaattct tgattttata gcctctttta
     9601 tttcttcttc atcactatat ccatctaaaa tttcttttaa agttggataa tgtacttttt
     9661 cttttatgtt taaatcatct atgtcaaaat caatgtgaga cttaatatcc acaaaattat
     9721 ttcctataac tctaactttt ttatcatcat ccattagtag atttactaca tttatacctg
     9781 cattttgtat ggctttagcc aaatcatagc ttattttttc tccagctttt acaaatactt
     9841 ctccagtttc tggatttatt atgtcttctg ctgaaatttt attcattatt ctataacata
     9901 aagcaagttt cttattgaat ttatatctac caacttttgc taggtcatat ctttttgggt
     9961 caaagaataa agcatttaat aaagatgatg cactttctac agtaggaggt tcacctggtc
    10021 ttaatttttt gtatatctct acaagacctt cttctactgt cttagtatta tctttttcta
    10081 atgtagcaga taatctctca tcttctccta aaaggtcaat tatctctgca tctgttccta
    10141 ttcctaaagc tctaagtaaa actgtaactg gttgttttct tgttctatca actcttacag
    10201 atattacatc attagaatct gtttcatatt ctaaccatgc tcctctatta ggaattacag
    10261 tagatgaaat caatctctta cctgttttat ctctttcttc cgcatagtaa acaccaggag
    10321 atctaactaa ttgacttact ataactcttt ctgctccatt tataacgaaa gttcctcttt
    10381 ctgtcattaa agggaagtca cccataaaca cttcttgttc ttttatctca cctgtttctt
    10441 tatttataag tcttacctta acctttagag gtgcacaata tgtagcatct ctctctttac
    10501 actcttctat atcgtacttt ggtttatcat ctagagaata gtcgacaaat tccaatataa
    10561 gattaccagt ataatcttct attggtgaaa tatcatcaaa cacttctttt aaaccttctt
    10621 ttaaaaacca ctcataggaa tctacttgaa tttctataag atttggcaca tcagctattt
    10681 ccttaatttt agaaaagctc attctagttc ttttacctat cgtgacagga tgtggcattc
    10741 acttttcacc tctcaataat taaaaataaa acaatagttc attctaacgc atctaataat
    10801 tttagcataa tgtcaagtat ttttcaatat attttttatc ttatatgtaa actatgcatt
    10861 atttttgatt ttttgtaaat tattttaagc atatattatg tattatgtac aattttccaa
    10921 tataaaatcc atatttttca tttataggtc taattttcta taaaaaattt tatacaagta
    10981 ccatcccccc tatttaatta taattccata ttaaaatgat tgtaaataat tacatttata
    11041 caaatatata caatttatta aaatatacaa aataaagacc ataaataaat ttaacttgga
    11101 attttgaacc tcaaaccttt ccaatataaa ttatatctat ggcctttata aaaatatcat
    11161 ttctactata actaatgcat aagctttcat tgcatattag taatttaatt atcctaatat
    11221 attatctgca aattgtggag taggtaaacc aaatcctcct gcaacttcaa gtaaatcccc
    11281 tgttataaat gatgagtcat cactagcata gaatagaaca gcttttgcta tatcatctgg
    11341 ttcccctata cgatttaaag gaacatgctt taaaaattct tttatgaact ctggagacat
    11401 attgtctaat gctgctttag ttgcaataag ccctggaagt acagcattac atctaacatt
    11461 gtctttagca tattgtgtag ctatgttttg agttaatgag ttgattgctg cttttgatac
    11521 acagtaagct attctagata aatcaggtaa tactgaacct atacttgata tatttactat
    11581 acttcctttt ccattcttta tcatatgagg aattgctgct ttacatggta aatacacact
    11641 ttttaaatta gtatttactg tgtcaaagaa attatctgta tctccagtta caaggtcttt
    11701 gtcaagagaa gggtttgttg aaccaaaatt gtttacaagt atatctatct taccttcttt
    11761 tttaactacc tcttctatca ttgaggtaaa ggtctcttct tcacgagcat taaagtaaac
    11821 aaacttagca caaccacctt ctgcacttat tttatttata acttcattag ctaattcttc
    11881 tgaacgagct gctaagtaca cagttgctcc attttttgct aatatctctg ctgatgctaa
    11941 tccaatacct tttgttgctg cagtaactac tgcaattttt ccttgtaatt tttccattat
    12001 taactcctcc ttgaatatgt cctttaaatc ctacaaattt cgatttttct aaatatctaa
    12061 cttattttaa aatttatatt tgttaattaa ttatttatta cattttattt ataaaacact
    12121 cgtgtatttt tttaaactaa aatgtaaaat tttacatttt agtttaatta tatactttat
    12181 atacagacat tacaacaatt gtttatattt taatttgata ataatgttaa attaaaatac
    12241 cattacacca tatatgatac ccttaattta gtactattat ataaattttt ttattttata
    12301 aaaatacttt ctttataatt ccaaatactt tctttatagt tttttataaa taaaaaaaga
    12361 tacccaatgg gtatcttttt aaagaaacta cttaacttct actttagctc cagcagcttc
    12421 taatttctct tttatttgat cagcttcttc tttagaagct ccttctttaa ctgtcttagg
    12481 agcattgtca actacttctt tagcttcttt taatcctaat cctgttattt ctctaactgc
    12541 ttttataact ccaacttttg aagaaccaac gtcagttaat actacatcaa actcagtttt
    12601 ttcttcagca gctggtccac cagcagctgc accagctacc attactggag ctgaagctga
    12661 tacaccgaat ttttcttcag cagctttaac taattcattt aattctaaaa ctttcatatt
    12721 ttctatagct tctaatattt gttctattgt catttttagc acctccgaat tttatttcaa
    12781 attaatattt ataatttttt agttaagcaa ttaagcttct tcttgacctt ctgccttttt
    12841 cgctattgca tctattaagt atgcgaagtt tgatactgga gcttttaagc taccaagtaa
    12901 tttagcgata agaacttctc ttgatggtat gttagccatt tcaacaatct tagattcatc
    12961 atagaatgca ccttccacaa tacccatctt taatttcatt tttggatgag aatccatgaa
    13021 tccttttaat attctagctg gagcaactgg atcatcatat ccaaatgcta tggcattagt
    13081 tccaactaat aattcatcat taaattgctc tataccaact tctttagctg ctcttctaac
    13141 taaagtattt ttgtatactt tgtaatctac accagcttct ctcatttgtt ttcttaactc
    13201 agttacttct tcaactgtta atcctttgta atctacaaca acagcagcag aagatttttg
    13261 taacttttca actatctcag aaacaacttc tgatttaatt tctatagctt ttctcatata
    13321 gatgtgcacc tccttcacca aataggctta gtatttaccg caacattata aaaagctttt
    13381 gttgccaaaa gtagacatca aaagctttag taatctcaat ttatctaaaa cctcggcggg
    13441 atattaagct ttcgcaccca ctatctacgg caaatctatt cttttttaca ttgacaagtg
    13501 atataataac atttttgtca acctgtgtca acagttttat tattcagctg ttcttgctgg
    13561 gtttatttta actccaggtc ccattgaaga agctactgtt atacttctta aatattgtcc
    13621 tttagcagca gctggtttag cttttattat agcatccatt aatgcagtaa agttttcagt
    13681 taatttttct ccaccaaatg atacttttcc tactggaacg tgtattatgt tagttttgtc
    13741 taatctgtat tcaactttac cagcttttat ttcatctata gctttagcta catcaaatgt
    13801 aactgttcct gatttagggt ttggcattaa acctttaggt cctaatactc tacctaatct
    13861 acctactaca cccatcatat ctggagtagc aactactata tcaaagtcaa accagttttc
    13921 accttgtatt ttttgaacta attcttcagc tcctacaaag tcagcaccag cttgttcagc
    13981 ttctttagct ttttcacctt tagcaaaaac taaaactctt tttgttttac cagttccatg
    14041 aggtaataca actgcacctc ttacttgttg gtcagcatgt cttgagtcaa cacctaattt
    14101 aatgtgtgct tctactgtct catcaaattt agctccagct atatctgaaa ctaatgttaa
    14161 tgcttctgat gcatcataaa atttagttct atctactttt tctaatgcac ctgcatatct
    14221 tttacctttt ttagccattt tattttcctc ctcgtggtta atttcggctt ctagcctccc
    14281 actttataaa aaaaagtgta tcttttaatt agtcttcgat tacaacaccc atgcttctag
    14341 cagtaccagc tatcatactc atagcagctt ctactgatgc agcatttaag tcaggcatct
    14401 ttaattcagc tatttctctt acttgagctg aagtcatttt agcaactttt ttcttgtttg
    14461 gttctccaga acctgatttt aagtttaatg cttttttaat taaaactgca gctggtggag
    14521 tttttgttat aaaactgaat gatctatctt gatatacagt tataacaact ggtattatca
    14581 ttccagcttg atctgcagtt ttagcattaa attcttttgt gaatcccatt atattaacac
    14641 catgttgtcc taatgctggt ccaactggtg gcgctggagt agcctttcct gcaggtattt
    14701 gtaattttat ttgacctata acttttttag ccattttgag cgcacctcct cagatttttc
    14761 tataatatag tattagattt tttctatacc ttcaagctct attacaaata gagtcctttt
    14821 accaaatgca tttatgcata ctttgacttc tctattttct aagtcaattt cttctatgtt
    14881 acctatttgt ccactaaatg gtccttgaga tacttttact gtatctccta tttcaaaatc
    14941 aatatcgcta tttactactt taggatctgt tgtgtctatc cccatagctt tgacttcgtc
    15001 ttcacttaat ggcactggtt ttgaaccagg tccaacgaaa cctgtaactc ccttagtatt
    15061 tcttactaca taccaagatt catcagttat tatcatttta accaaaacat aacttggata
    15121 aactttacgt tgtctagttt tttcttttcc agttttagta gtttccacta cttcttctgt
    15181 tggaacaact acttgtctta tgcagtcttc catacctctt gttttaactg ctttctcaat
    15241 tgtagcttta actttatttt catgtcccga ataggtatga actacatacc aacttgcttc
    15301 ttgtaattct gacatttaac ttacctcttt tcgtctattt tagtaataac gctagtgcac
    15361 cagataatat agtgtctata ccccatacta atatagtgca tgaaataact acagttaaaa
    15421 ctatacttgt gtttttaaac agttcctttt ttgtcggcca tgtaactctt tttaattctt
    15481 gtttagtttc ttttaagtat ccaaacaaac taaacctttt tttagttttt gcaccgtcat
    15541 ttttttgggc agccattcca tactcacatc cttataaaaa actattttgt ttctttatga
    15601 gttgtatgct ttttacagaa tctacaatat ttttgtaatt ctattctgtc tggattgttt
    15661 ttcttattct tagtagtgtt gtagtttctt tgcttacact ctgtacatgc taaagttact
    15721 ttaactctca tctgatacac ctccaacttt gtaatacaat aatatatatt gttaatatat
    15781 gtgaatataa tatctttaaa atatgtattt attaaaaatc tacagtattc aagatattat
    15841 taacttccta taatcattac cttgtataag ttatcacaaa atcctatgct gtgtcaatgt
    15901 ttttgtattt ctatgttaaa aaaagaggag cataacccct ctttttgtta ttccttttaa
    15961 tccatcagtt tagtaaagaa ttactctatt attgtagcaa caactcctga agctactgtt
    16021 cttccacctt ctcttattga gaatcttaat ccctcttcta caactattga gtttattaag
    16081 tctacttcca ttgttacgtt atctccaggc attaccatct ctattccttc tggtaactta
    16141 caagctcctg ttacgtctgt tgttctgaaa tagaattgtg gtctatatcc atcaaagaat
    16201 ggtgtatgtc ttccaccctc ttctttttta agtacatata cttctgctgt aaactttgtg
    16261 tgtgccttta ctgatccagt ctttgctagt acttgtcctc tttctatctc gtttctttgt
    16321 actcctctta ataatgctcc tatattatcc cctgcttgtg cttggtctaa taattttctg
    16381 aacatctcta ctcctgttac tactactttt cttggtgctt ctgttaatcc tactaactct
    16441 acttcgtctt gtacttttag tactcctctt tccactcttc ctgttgcaac tgttcctctt
    16501 cctgtgattg agaatacgtc ctctactggc attaagaatg gtttatctgt atctctctct
    16561 ggagctggta tatactcatc tatttgctcg aataattcta ctatcttatc tccccactc
//
LOCUS       DAMJXI010000078        15958 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.083, whole genome shotgun sequence.
ACCESSION   DAMJXI010000078 DAMJXI010000000
VERSION     DAMJXI010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15958
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.083"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            146..688
                     /locus_tag="PC465_003165"
     CDS             146..688
                     /locus_tag="PC465_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2650446.1"
                     /translation="MKICITVGHSILKGGKSTGVNGIVDEYNYNKKLAPMLAEMLISQ
                     GNTVDVIICPERHFMSEREEFFYRVPKVNSGKYDLLVELHLNKADGTQCGTEVLYYGT
                     EGLEYAKRVSNRLGELFENRGAKKRENLYILRNTNPVAIQIESFFCDNVNDCNKANES
                     GYDYIARLITEGILNKDINM"
     gene            1016..2509
                     /locus_tag="PC465_003166"
     CDS             1016..2509
                     /locus_tag="PC465_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2650447.1"
                     /translation="MKYTFEKFKLNEKILKSLKSLGYNIPSRVQREVIPKLLKGQNLV
                     VRSKTGSGKTASFAIPLCENINVDYNNIQALIVVPTRELALQVKDEISDIGRLKKVRC
                     SAIFGKQSIKDQIAELKQRVHIVVATPGRILDHINRGSIKLENVKYLVIDEADKMFNK
                     GFVEQMEKILLNLPKEKIVSLFSATIDEEIKYICEKYMLDYSVINIEENESDTNQKTR
                     QIDDKIIKANGREKYILLKELIYSENPKSVIIFCNTKEKVSKLYNKMSKEGFLIRELH
                     ADLSQERRIFVIKDFKNQKFNILVSSDVASRGIHIDDISLVINYDVPQDKENYIHRIG
                     RTGRKGNSGKAITIVTEKDEKYIENIETYIGYKINELKDIEKSRITHGKVLFEEYSKG
                     ILKKVSKRKKVDKNSYKSKDIKLNIESEVVKLYLNAGKKKKIRVLDIVGAFSNIKGIT
                     NDDIGVIEVQDLCSYVDILNYKGDLILKKYKEIPIKKKMVKVKRDIR"
     gene            2583..2816
                     /locus_tag="PC465_003167"
     CDS             2583..2816
                     /locus_tag="PC465_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650448.1"
                     /translation="MKAEDMKRKVSPIDLERILVTGGVIKHEDSIWLLDFWGNKDIAG
                     ILLMPSTRHVILHLNDCCKWKEYFRTKKKFYRS"
     gene            2972..3736
                     /locus_tag="PC465_003168"
     CDS             2972..3736
                     /locus_tag="PC465_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2650449.1"
                     /translation="MAYFNYNDKQCYYNEIGDGTPLLFLHGNTASSKMFNDIIDFYKD
                     EYKVILIDFVGHGKSQMVDKFSADLWFDEAMQVICFLEAMNYKKVNIIGSSGGALVAL
                     NVALERPDLVNKVIADSFEGEVPLESFVQNVKIEREASKQDDGAKAFYIYNQGENWEK
                     VVDNDTEAIFEHYKTIGKFFHKPLETMQPEVLLTGSREDEFVSLISSDFFENTFSLLL
                     EKIKNGKMYLFDKGGHPAILSNGLDFSNVAKKFLEE"
     gene            complement(4021..7200)
                     /locus_tag="PC465_003169"
     CDS             complement(4021..7200)
                     /locus_tag="PC465_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2650450.1"
                     /translation="MKIDMIYKLIRRNTEPSRWSRGVKYYTNQLVDYIDIDIDDLQNN
                     LLTFRGGVNSEDNYSFYFNSITIDIKHFKIIENDCSCADCQSKGKSIFICKHIVAIVI
                     KSLKQIKNKKDVPPILIDILGADKDKLSNTNSKTSLDLSKQLLSLLDNTKRERVNLDV
                     LINVDSNKAIAEFKIGIDKMYILKNITEFAYSKLNGYELDFGKKFTYNPNTHYFADED
                     EKLVDIIEEYGTNLSYNFSSSHSKKFMEINASSLKQFLNAIKYKDFTLIFSKEEYHPK
                     ILNDTLPVRFDFKNIEDKIVLYSKDSLPVPLTKKNDVLLYDGNIYLLSHKKAHDYSKI
                     YQILSKTKELKFDKEDSKDVLGLLVPRLKSISQEVHLDDNIKNNITKDFKSEFYFDMI
                     DGNICCDVKYIYDDEDKKFVLPNIQKEATIENKLTSSQFTKENNHYVFKGTDHDLFTF
                     LDLQLESLKEFGDIYYSEKFKLKKIYNASSIQASINQTNQNYLEFNFNISDINPKEYK
                     DILKAFQEKRTFYKLKDGNFIDLSERETKDFFELVENLDIMDKSKNNKIHKNKALYIN
                     DVIRSKNLKFIDGKKELDSICEKFRNFDSINLEIPTNLNANLRDYQINGLNWFKVLDY
                     YKFGGILADEMGLGKTIQTIAFLLSLSNKKSLIVTPTSLIYNWKNEFEKFAPDIKVLL
                     IHGNKRDREKCFMKLENFDVILTTYGTLRNDLDKYSEIKFDYCILDEAQNIKNPVALV
                     TESVKSINAENKFALTGTPMENNLLELWSIFDFIMPGYLYSKAKFQELFINKEDNVKN
                     LKKLIKPFILRRSKKQVMKELPDKIEKNFFVELNKEQKKIYSVYSKDIQDKMKDKNLK
                     KDKIVIFSYLTKLRQLCLDPSIVVKDYNKKSSKIETCLEILRDSINENHKILLFSQFT
                     SVLKNISKELDKYKIKYHYIDGKTNAKERLELVDEFNNSMDKKVFLISLKAGGTGLNL
                     TSADMVIHFDPWWNPSVENQASDRAHRFGQKNSVQVIKLIAKGTIEEKIIKLQESKKE
                     LINQFINGELSNEGVLKSLSDEEIINLFN"
     gene            7481..9658
                     /locus_tag="PC465_003170"
     CDS             7481..9658
                     /locus_tag="PC465_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2650451.1"
                     /translation="MYNKYNNLYLLLGKENVNMDSYRQLKAKIPCKETGIEIKRTLCD
                     ICSPGVHCGIDAYVKDGKVIKIEGTKEHPMNKGLLCTKGLCNREYIYREDRIKTPLKR
                     IGKRGEGKFKPISWDEAYREIAEKLNRVKSEYGAKHVAFFTGYGKWYRPFLQRFASSF
                     GSPNYGTESSSCSTSAQMAGNVATGRNFTMQDMENAKTYLGWGFNPYYSKFLNSVNLI
                     KLKEKGLKFIIVDPRITPTTQKLADLHLRIKPGTDGALALGMANLFIQKNLIDREYIE
                     KYVHGFNEYKEYVKLFDLDTVSRITGVSKDNIVKAVEMLSQGPFCINESAAPIVHHQN
                     GFQNYRAMMSLSAITGNYDRIGGNIPKQDYFAGKIGGFQTLEKEFVKEVLPKNINERI
                     GGERFPLWNEMVTQFQAMDLPRQIEEKTPYEIRALFCHGINARMFPNSGRLFKALNSV
                     DFFVNIDLFMTDTSKYADILLPACTSFEREECKSYPGGYITYTKKVIDKLYDSKSDVE
                     ILSDLANAMNIDDDLLKAGYEASVRHMFKNTCVDVDKLKESDLPLKCKDFKPYIVGSY
                     TREGYDTSTSRFELKSTIIEKYKDFGLDALPTYRGFNDNIDDEYTHLLTSGARISNAL
                     HSRLHDIKLSRILKNEASCDISSLDAKELGVISGDYIKITTKIGSLDVKVNVTDRVLY
                     KNIHMYHGYREADINSIICDNFDPYSGFPAYRSCKCKIEKMNR"
     gene            9672..10094
                     /locus_tag="PC465_003171"
     CDS             9672..10094
                     /locus_tag="PC465_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2650452.1"
                     /translation="MKSLFKFNKELCTACGACLLACIDQNDNNIDNGELFRHVFTIEE
                     GENIEYFSLACIHCNEPKCLGVCPKNCFKKEEGFVVLDNQNCIGCKLCEKACEYGALI
                     YGNDGKANKCNGCIERYKCGMDSPCVMVCPTGALKFNK"
     gene            10502..11305
                     /locus_tag="PC465_003172"
     CDS             10502..11305
                     /locus_tag="PC465_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF2650453.1"
                     /translation="MKKLKLIIMFALVSALLVTGCSSGNNKNKEEQKVIRVATSGTYY
                     PFAFKDKDKLKGFEVDFWDEFAKRTNCKVEWVLTDFSGLFGLLEADKADAVSAQLTAT
                     PEREKKYAFSDAYNYSGTNIIVREDDTSIKSIDDLVGKKVGVGTGAVANEILKEKYPN
                     DEIKIVNYSSATLKGNYQDLEMGRLDAVVAQDVEALIAIKEQKLNLKMIEPPIQFGAC
                     SFALQKNEKGEKWTKEINEVIEEMYKDGTLTKISENWLGKDITKEPINE"
     gene            11298..11966
                     /locus_tag="PC465_003173"
     CDS             11298..11966
                     /locus_tag="PC465_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF2650454.1"
                     /translation="MSNFNFEFCLSIFPFLIKALGITILISIVAFFLSILLGVILAFF
                     TQTKSKVLQYITRVYVSFFRGTPLLIQIFFFYFGFPMIFSFMKDCSPYLAIVICLGVN
                     SSAYMAEIIRASIESVDKGQQEACYAFGLSKYQSMVKIILPQAATSAVPPIVSCTLDI
                     IKGSSLGLTIGIQDLMGVAQVEAASSFKYFEIYMITILIYWAVSIILSNIQSKVEKRI
                     RRAY"
     gene            12202..12864
                     /locus_tag="PC465_003174"
     CDS             12202..12864
                     /locus_tag="PC465_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF2650455.1"
                     /translation="MAFNMKYFLELFPTIMKSFNVTVILAISSLVFSLIIGTIVALSS
                     YYKVKVLNQICKVYVSIFRGTPLMPQLFFLYFGLAYMSDFVKNMDPVFATSIVLSLNM
                     GAYMSETIRASILSIDTGQIEAAYAMGLTNLQTMKRIVIPQAVRVALPSLFNNFIDLI
                     KGSSVAFVVGVNDIMGAAKLQGALSFKFFEVYGAVMVIYWCIITPLGWGQKKLEKKIS
                     NY"
     gene            12924..13721
                     /locus_tag="PC465_003175"
     CDS             12924..13721
                     /locus_tag="PC465_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2650456.1"
                     /translation="MIKRNIIKCLVAVLSLTFVITGCSKKEEVKNEKVITVASSNSAD
                     PYSYVDNGEHKGFEVDMWKEIGKRSGYKIKMEPTGFSSIFGMLDSGKVDVAANFFGMS
                     KERLEKYDASIPYGSDSVCIAVKDGNNEINKLEDLKGKVVAVSEGSQGQQVATSVNKD
                     NLFQEKVYGDGTSGLQDLDLGRVSAWIDAELTIVGDAKKANMKVRVLDKKLSATNIAY
                     FFKKNDDKSKTIKEDVNKAIEEMLADGTVKKISEKWFGMDVSADIQK"
     gene            13839..15029
                     /locus_tag="PC465_003176"
     CDS             13839..15029
                     /locus_tag="PC465_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2650457.1"
                     /translation="MEVLQMIETKIKSIALKNREKIIKIRRQIHSNPELAFKEYKTSK
                     LIKEELNKLNIEYINIAGTGVLATIKGKNNGGKTILLRADMDALPIKEENDLEFKSIN
                     DNMHACGHDAHVSWLLGTAMILNDIKEELNGNVKLLFQPGEEKGGSDIVIKENVLEGV
                     DALATGHCWPTIESGKIGIARNCAMAATNTFEITIIGKGGHGAEPHNCIDPIAVGNAV
                     YSSIQQIVSRKIDPVVPVVVSVCSFNSGVSKNIIPDVCTLQGTIRAISKEQVIEVSKI
                     LEYIVKNVCKAHGADCKFEKSTGGDAVINDKNMIEIGRESACKILGAENVEIIDFPAM
                     TGEDFAIYMKEKPGLFMYIGVGDKEKNINYRLHSNKFNIDEKCLSIAPSLFSQLTVDY
                     LCQL"
     gene            15138..15887
                     /locus_tag="PC465_003177"
     CDS             15138..15887
                     /locus_tag="PC465_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDF2650458.1"
                     /translation="MIKVENLHKSFKGTEVLKGINLEISQSEVVAILGSSGTGKSTLL
                     RCLNYLVEPTKGKIMIGDVKVDVEKATKKDITNLRKHTSMVFQNYNLFKNKTALENVM
                     EALIVVHKKSKKEAREISLKLIDKVGMLDRKDFYPSKLSGGQQQRIGIARAMAVNPNV
                     ILFDEPTSALDPELVGEVLSVIKSLAKEGITMLIVTHEINFAKEVADKIIFMDNGVIA
                     EEGTPDEIFNNPKNERTAKFLNIIRKEEVFS"
BASE COUNT         6196 a         1677 c         2650 g         5435 t
ORIGIN      
        1 atgataaaat aagacaaata tgttaaaaaa atgataatca cggagaactt ttaccttctt
       61 caattaatat attattatta gtaataactt taaaattata ttactattat ataaaaattg
      121 gcttaaaaga aggtgaaaaa agtaaatgaa aatatgcata acagtaggtc atagtatact
      181 aaaaggtggt aaaagtacag gtgtaaatgg tatagttgat gaatacaatt ataataaaaa
      241 attagctcct atgttagctg agatgcttat aagtcaaggt aatacagtag atgtaataat
      301 ttgtccagaa aggcacttta tgtcagaaag agaagaattt ttctatagag ttccaaaagt
      361 aaacagtggt aaatacgatt tattagtaga gctacattta aataaagctg atggaacaca
      421 atgtggtaca gaagtgcttt actatggcac tgaaggatta gaatatgcta aaagagtatc
      481 taatagactt ggagaattat ttgaaaatag aggagctaaa aaaagagaaa atttatatat
      541 attgagaaat acaaatccag ttgcaataca gattgaaagt tttttctgtg ataatgtgaa
      601 tgattgtaac aaagcaaatg aatcaggtta tgattatata gcacgattga ttacagaagg
      661 tatattgaat aaagatataa atatgtgaga ttatggtgat ttaggtattg attaatacct
      721 tttaatatta gatataaata aaaatacaat gtattagtat aatttaaact ttcaaaagat
      781 agattagttt gattattgac aagagatacc tccttgaaaa tattgattta tcagtatatt
      841 taaggaggta tttaaatata aaaatttaat taatttgcta ctaaactata ggtttataga
      901 gtatatattt ttatcttcag tctaataaat aatataaaaa tagtagaacc ttgtattata
      961 ataatataat gtagaaaaat atatagataa gataaatata ataaggtggt aatatatgaa
     1021 atatacattt gaaaaattta agttaaatga aaagatactt aagtcattga agagtttagg
     1081 atataatata ccttctagag tacaaagaga agttattcca aaattattaa aaggtcaaaa
     1141 cttagtagtt aggtcaaaaa caggaagtgg aaagacagca agttttgcaa tacctttatg
     1201 cgagaatata aatgtagatt acaataatat tcaagctctt atagtggttc caacaagaga
     1261 attagccttg caagtaaaag atgagatatc agatataggg agactaaaga aggtgagatg
     1321 tagtgctata tttggcaaac aatctataaa agaccaaata gctgaattga aacaaagggt
     1381 tcatattgtt gtagctactc caggcagaat acttgatcat ataaatagag gttctattaa
     1441 gttggaaaat gtaaagtatt tagtaataga tgaggcagat aaaatgttta ataaaggttt
     1501 tgttgaacaa atggaaaaaa tattattaaa tttacctaag gagaaaatag taagtctttt
     1561 ttcagctaca atagatgaag agataaaata tatatgtgaa aaatatatgc tagattacag
     1621 tgttataaat atagaagaaa atgagagcga tactaatcaa aaaacaagac aaatagatga
     1681 caaaataatc aaggcaaatg gaagagagaa gtacatcctt ttaaaagaat taatatacag
     1741 cgaaaatcca aagagtgtga taatattttg taataccaaa gagaaagtat ctaaattata
     1801 taacaagatg agtaaagagg gttttttaat aagagagtta catgcagatt tatcacaaga
     1861 aagaagaatt tttgtaatta aggattttaa aaaccaaaaa tttaatatat tagttagtag
     1921 tgatgtagcg tccagaggaa tacatattga tgatatttct ttagtaataa attatgatgt
     1981 gccacaagat aaagaaaact atatacatag aataggtaga actgggagaa aaggaaatag
     2041 tggaaaggca attactatag taactgaaaa ggatgaaaaa tatatagaga atatagaaac
     2101 gtatatagga tataaaataa atgaattaaa agatatagaa aaaagtagaa ttacacatgg
     2161 caaagttttg tttgaagaat attcaaaagg aatcctaaaa aaagtatcaa agagaaaaaa
     2221 agttgataaa aattcttaca aaagtaaaga tataaaacta aatatagaaa gtgaagttgt
     2281 taaattatat ttaaatgctg gtaagaagaa gaaaataaga gttttagata tagttggtgc
     2341 atttagtaat ataaaaggta taactaatga tgatataggt gtaattgaag ttcaagattt
     2401 atgttcatat gtagatatat taaattataa gggagatttg atattaaaaa aatataagga
     2461 gatacctata aagaaaaaaa tggttaaagt gaaaagagat atacgataat ttagtcaata
     2521 ttgatgaatt gctttgttat cgaaatgaag ttgcaaaaaa cacaatagaa gttgttaagg
     2581 atttgaaagc tgaagatatg aaacgaaagg tctctccaat tgacttagaa aggattttgg
     2641 tgactggagg agtaataaag catgaagatt ctatttggtt gttggacttt tgggggaata
     2701 aagatattgc tggaattttg cttatgcctt ctactcgtca tgttatactt catttgaatg
     2761 attgttgtaa atggaaggaa tattttcgta caaaaaagaa attttacaga agttaaatta
     2821 taataaatta gacaaacaat agataaatta gcaaggaatg ttgattttat ctacattcta
     2881 agttatacta tttttaagtg gctaatggaa tagtcatttt aaatataagt aataaatata
     2941 tacctatagg gatattaaag gggggaaata tatggcatat tttaactata acgacaaaca
     3001 gtgctactat aatgaaattg gggatggtac accattactt tttttacatg gaaatacagc
     3061 ctcttccaag atgtttaatg atataatcga tttttataaa gatgaatata aagtaatatt
     3121 aattgatttt gtaggtcatg gaaaatctca aatggtcgat aaattttctg ctgacttatg
     3181 gtttgatgag gctatgcaag tgatatgttt tttagaagca atgaactata aaaaagtaaa
     3241 cataattggt agtagtggag gcgctcttgt tgcattaaat gttgcacttg agagacctga
     3301 tttagtgaat aaggtaattg cagatagttt tgaaggagaa gttcctctag agtcatttgt
     3361 acaaaatgtg aaaatagagc gtgaagcatc taagcaagat gatggtgcaa aagcttttta
     3421 tatttataat caaggagaaa actgggaaaa agttgtagat aatgatacag aagctatttt
     3481 tgaacattat aaaactatag gaaagttttt tcataagcct ctagaaacta tgcaaccaga
     3541 ggtgctttta acaggaagta gagaagatga gtttgtatct ctaatatcta gtgatttttt
     3601 tgaaaatact ttttcattac ttcttgaaaa gattaaaaat ggtaaaatgt atttgtttga
     3661 taaaggtggt catcctgcaa ttttatcgaa tggattagat ttttcaaatg tagcaaagaa
     3721 atttttagag gaataattta accaaaattt acaataatga aaactgtaaa atggattgca
     3781 aaacttacaa aagtgagtgt acatatactt cattattatg atgaaatagt attgttaaaa
     3841 caaaatattc taatagtcaa gttattacat ttgtatatgc aatatgtata gaaagagata
     3901 tcattagatt gtaaagttgg gattaaataa caatattaaa ttttatttat tcagatattt
     3961 tagcttaact atataaatgt tagaacaaat ttatatagtt aagctgtagg attaaataat
     4021 ttagttaaat aagtttatta tctcctcatc agatagactt tttaatacac cttcattaga
     4081 aagttctcca tttataaatt gatttataag ctctttttta ctttcttgta attttattat
     4141 tttttcttct atagtccctt tagcaatcaa ttttataact tgtactgaat ttttttgacc
     4201 aaatctatga gctctatcac tagcttgatt ttctactgat ggattccacc atgggtcaaa
     4261 gtgaattacc atgtcagcag atgtaagatt taaaccagtt ccgcctgctt ttaaagatat
     4321 taaaaaaact tttttatcca tactattatt gaactcatct acaagttcaa gtctttcttt
     4381 ggcattagtt ttaccatcta tataatggta tttaatttta tacttatcaa gttccttact
     4441 tatgttctta agcacagaag taaattgtga aaacaataat attttgtggt tttcgtttat
     4501 actatcccta agtatttcta aacatgtttc aatttttgaa ctttttttat tgtaatcttt
     4561 tactactata cttgggtcta aacaaagttg tcttagttta gttaaataag aaaatataac
     4621 tattttatct ttctttagat ttttatcttt cattttatct tgtatatctt ttgaatatac
     4681 actatatatc tttttctgct ctttattcaa ttcaacaaaa aagttttttt caatcttatc
     4741 tggaagttct ttcataactt gttttttact tcttctaaga ataaaaggtt ttatcaattt
     4801 tttcaggttt ttaacattat cttctttatt tataaacaat tcctgaaact ttgctttact
     4861 atatagatag ccaggcatta taaaatcaaa tatagaccat aattctagta gattattttc
     4921 cataggtgta ccagtgagtg caaatttatt ttctgcattt atacttttta cagactcagt
     4981 tactaaagct actggatttt ttatattttg agcttcgtct aatatacaat aatcaaactt
     5041 tatttcacta tatttgtcta aatcatttct aagagtacca tatgttgtaa gtattacatc
     5101 aaaattttct aatttcataa aacatttttc tctatctctt ttatttccat gtatcaataa
     5161 aacttttata tctggagcaa acttttcaaa ttcatttttc caattataaa tgagtgatgt
     5221 cggtgtaaca ataagacttt ttttattaga taatgataat aaaaatgcaa tagtctgtat
     5281 tgttttacca agacccattt catcagctaa tataccacca aatttataat aatctaaaac
     5341 tttaaaccaa ttgaggccat ttatttgata gtcacgaagg tttgcattta aatttgtggg
     5401 aatttctaaa tttatgctat caaaatttct aaatttttca catatactgt ctagttcttt
     5461 tttaccatct ataaacttta aatttttact acgtattaca tcatttatat atagagcttt
     5521 atttttatga attttattat tttttgattt atccattata tctagatttt caactaattc
     5581 aaaaaaatct tttgtttctc tttctgataa atctataaag tttccatctt taagtttata
     5641 aaaagtacgt ttttcttgaa aagctttcaa aatatccttg tactcttttg gatttatatc
     5701 agatatatta aaattaaatt ctaggtaatt ctggttagtc tgattgattg aagcttgaat
     5761 tgatgaagcg ttatatattt ttttcaattt aaacttctca gaataatata tatctccaaa
     5821 ttcctttaga gattctaatt gtaaatctaa aaatgtaaat aggtcatggt cagttccttt
     5881 aaacacataa tgattatttt cctttgtaaa ttgtgaagaa gtaagtttat tttcaatagt
     5941 ggcttccttt tgtatgttgg ggagcacaaa ttttttatct tcatcatcat atatatactt
     6001 tacatcacaa catatgttgc catcaatcat atcaaagtag aactcagatt taaaatcttt
     6061 tgttatatta ttttttatgt tatcatctaa atgaacttct tgagatatag attttaatct
     6121 aggaactagc aatcctaaaa catccttaga atcctcttta tcaaatttta actctttagt
     6181 ctttgataat atttgatata tttttgaata atcatgagct tttttatgtg ataataaata
     6241 gatattgcca tcatataaaa gtacatcatt ttttttagta agtggaacag gtagtgaatc
     6301 tttagaatat aagactattt tatcttctat atttttaaaa tcaaacctta caggtagagt
     6361 atcatttaat atctttggat gatattcctc tttagaaaaa ataagggtaa aatccttgta
     6421 cttaatagca tttaaaaatt gttttaaaga gcttgcattt atctccataa atttttttga
     6481 atgtgatgaa gaaaagttgt atgaaagatt tgtcccatat tcttctataa tatctactaa
     6541 cttctcatct tcatcagcaa aataatgagt gttggggttg taagtaaatt tcttcccaaa
     6601 atctaattca tatccattaa gttttgaata tgcaaattca gtaatgtttt ttaaaatgta
     6661 cattttatca attcctattt taaattcagc aattgcttta tttgaatcca catttatcaa
     6721 tacatctaaa ttaacccttt ctcttttagt attgtctaac aaagaaagta attgcttgct
     6781 taaatctaag ctggttttag aatttgtatt agaaagctta tccttatctg cacctaatat
     6841 atctattaga ataggaggaa catctttttt attttttatt tgttttaagc tttttatcac
     6901 aatagcaact atatgcttac atataaaaat acttttgccc tttgattgac agtcagcgca
     6961 actacaatca ttttcaatta tcttaaagtg ctttatatct atagttattg aattaaaata
     7021 aaagctataa ttatcttcag aattgactcc accacgaaat gtcaacaggt tattttgtag
     7081 gtcatcaata tctatgtcta tataatcaac taattgatta gtataatatt ttacacctct
     7141 tgaccatctt gatggttctg tatttcttct tattagttta tatatcatat ctattttcat
     7201 attattcacc ttacctcact gtatatatta taatctaaat gcattcaatt tacactctaa
     7261 atttaagact aaaattaagg cagatatgaa tagcttttat ctatcacaat atatgtgtaa
     7321 ataacaattt actattagat ttttattgaa ttatcttata aactatgaat gaaaaataat
     7381 tatataaata gattattaat aaatataaaa tcttattatt aaaaatattc ttagaaatta
     7441 cactatataa aatataaagt atgatatttg aataaaaaga atgtataata agtataataa
     7501 tttgtattta ttattgggaa aggaaaatgt taatatggat agttatagac aacttaaagc
     7561 taaaataccc tgtaaggaaa caggtataga aataaagagg actttatgtg atatttgttc
     7621 tccaggagta cattgtggaa ttgatgcata tgttaaagat ggtaaagtaa taaaaataga
     7681 aggtacaaaa gaacatccaa tgaataaagg gttgttatgt accaaaggtc tttgcaatag
     7741 agaatatatc tatagagaag atagaataaa aacacctcta aaaagaattg gaaaaagagg
     7801 tgaaggaaaa tttaaaccaa tatcatggga tgaagcttat agagaaatag cagaaaaatt
     7861 aaatagagta aaatctgagt atggagcaaa gcatgtagct ttttttacgg gttatggaaa
     7921 gtggtataga ccttttttac aaaggtttgc atcttcattt ggttcaccta attatggtac
     7981 agaatctagt tcatgttcaa catcagcaca gatggctgga aatgttgcta ctggaagaaa
     8041 ctttacaatg caagatatgg agaatgcaaa aacttattta gggtggggat ttaatccata
     8101 ctactctaaa tttttaaata gtgtgaatct aataaaatta aaagaaaaag gtctaaaatt
     8161 tataattgta gaccctagaa taacaccgac aactcaaaaa ctagcagatt tacatttaag
     8221 aattaaacct ggaactgatg gagctttagc tcttggaatg gcgaatctat ttatacaaaa
     8281 gaatttaata gatagagaat acatagaaaa gtatgtacat ggatttaatg aatataaaga
     8341 atatgtaaaa ttatttgatt tagatactgt aagtagaatt acaggagttt ctaaagataa
     8401 tatagtaaaa gctgtcgaga tgttgtcaca aggtccattt tgtataaatg aaagtgcagc
     8461 tccaatagtt catcatcaaa atggatttca aaactataga gcaatgatgt ctttatccgc
     8521 tataacaggt aattatgata gaataggtgg aaacatacca aaacaagatt actttgctgg
     8581 taagataggt ggattccaaa cactagaaaa agagtttgta aaagaagttc tacctaaaaa
     8641 tataaatgaa agaattggtg gagaaagatt tcctctatgg aatgaaatgg tgactcaatt
     8701 tcaagctatg gatttaccta ggcaaataga agaaaagaca ccatatgaaa taagagcttt
     8761 gttttgtcat gggataaatg ctagaatgtt tcctaattca gggagacttt ttaaagcgtt
     8821 gaatagtgta gatttttttg tgaatataga tttatttatg acagatacat caaaatatgc
     8881 agatatactt ttacctgcat gtacatcatt tgagagagaa gaatgtaaga gttatccagg
     8941 agggtatatt acatatacca aaaaagttat tgataaatta tacgattcaa aatcagatgt
     9001 agaaatactt tcagatttag caaatgctat gaatatagat gatgatttat taaaagcagg
     9061 ttatgaagca agtgtaagac atatgtttaa aaatacatgt gtagatgtag ataaacttaa
     9121 agaaagtgat ttaccattaa aatgtaaaga ttttaagcca tatatagtag gttcatatac
     9181 aagagaaggg tatgatacta gcacttctag gtttgaatta aaatctacaa ttattgaaaa
     9241 atataaagat tttgggctgg atgcactacc aacatataga ggatttaatg ataatataga
     9301 tgatgaatat actcatttat tgacatcagg agcaagaatt tcaaatgcac tacattcaag
     9361 acttcatgac atcaaacttt caagaatatt aaaaaatgaa gctagttgtg atatttctag
     9421 cttagatgca aaagaattgg gtgttatcag tggagattat ataaaaataa ctactaagat
     9481 aggaagtttg gatgtaaaag tcaatgttac tgatagagtc ttatataaga atatacatat
     9541 gtatcatgga tatagagaag ctgatataaa tagtattatt tgtgataatt ttgaccctta
     9601 tagtggattc cctgcgtata gaagttgtaa gtgtaagatt gaaaaaatga atagataaat
     9661 ggagagatat aatgaaaagt ttatttaaat ttaataaaga attatgtaca gcatgtggag
     9721 catgtttgct tgcatgtata gaccaaaatg ataataatat agacaatggt gaacttttta
     9781 gacatgtatt tacaatagag gaaggtgaaa atatagaata tttttcatta gcatgtatac
     9841 attgtaatga gccaaaatgt ttaggtgtat gtcctaaaaa ttgttttaaa aaagaagaag
     9901 gattcgttgt attagacaat caaaactgta tagggtgtaa actttgtgaa aaagcttgtg
     9961 aatatggagc cttaatttat ggaaatgatg gtaaggcaaa taagtgtaat ggttgtattg
    10021 agagatataa gtgtggtatg gattcacctt gtgtaatggt atgtcctaca ggagcattaa
    10081 aatttaataa ataaattaaa tatagagaat gacttatact taggtataag atatttttac
    10141 aaaaagctgt attgagtttg ttataatgaa aactcaatat agctttttta tggatatagt
    10201 tggatactat aatgtgattc ttagtaatag ttttttgcta ttggacaaag actgtaaaac
    10261 atattaaact tatgttgttc aaagtcgaag tataatataa taactagaaa attggtttat
    10321 agtgctataa aagcaaattt agtaaggtat aaaatcagag gcaatccttt actataatat
    10381 caatatttgg gagttctgtt attgcagagc tattaaacaa ttataatggt acaagtgatt
    10441 caacctttga aaatgtatta tataaaaaat taaaataaga ttaaaaagga gagaataaat
    10501 tatgaaaaaa cttaaattaa ttattatgtt tgccttggta tcagcactgt tagttacagg
    10561 atgttcatca ggaaataata aaaataaaga agaacaaaaa gttataagag ttgcaacatc
    10621 aggaacatat tacccttttg cttttaaaga taaagataaa cttaaagggt ttgaagtaga
    10681 tttttgggat gaatttgcta aacgaactaa ttgtaaagtt gaatgggtat taactgattt
    10741 tagtggatta tttggattat tagaagctga taaagcagat gctgtatctg ctcaacttac
    10801 tgcaacacct gaaagagaga aaaaatatgc tttttcagat gcttataatt atagtggaac
    10861 aaacattatt gttagagaag atgatactag tataaaatca atagatgatt tagttggcaa
    10921 gaaagtaggt gtgggtactg gagcagtagc aaatgaaata ttaaaagaaa aatacccaaa
    10981 tgatgaaata aaaatagtaa attattcaag tgcgactctt aaagggaatt atcaagacct
    11041 agaaatggga agattagatg cagtagttgc gcaggatgtt gaggctttaa tagctataaa
    11101 agaacaaaaa ttaaatctta aaatgataga acctccaatt caatttggtg cctgttcttt
    11161 tgcgcttcaa aaaaatgaaa aaggtgaaaa atggacaaaa gaaattaacg aagtaattga
    11221 agagatgtat aaagatggga ctttgactaa aatatctgaa aactggctag gaaaagacat
    11281 tactaaggag cctattaatg agtaatttta attttgaatt ttgtctaagt atatttccat
    11341 ttttgattaa agcattggga ataacaatac taatatctat tgttgcattt tttttatcaa
    11401 tattattagg tgtaatactt gcctttttca cacagacaaa atcaaaagtt ttacaataca
    11461 taacaagagt gtatgtttca ttctttagag gaacaccact tttaattcaa atatttttct
    11521 tttattttgg atttccaatg atattttctt ttatgaaaga ttgttcacct tatttagcaa
    11581 tagtaatttg tttaggtgta aattcatctg catatatggc tgaaattata cgagcatcta
    11641 ttgagagtgt tgataaagga caacaggaag catgttatgc ttttgggtta agtaaatatc
    11701 agtcaatggt taaaataatt ctacctcaag cagctacatc tgcagtacct cctattgtaa
    11761 gctgtacact ggacataatt aaaggttctt ctttaggttt aactatagga atacaagatt
    11821 taatgggagt agctcaagta gaggctgctt caagttttaa atattttgag atatatatga
    11881 taacgatatt aatttactgg gcagtatcta taatattgag taatatacaa agcaaagttg
    11941 aaaaaagaat aagaagagca tattagattt caatatttaa aaatgggatg atatagatat
    12001 attattactt gtaaataaat ttttaatttt agaaaaataa acttagtaat ctaaattatt
    12061 gagaaaatat agtatcaaaa tggactgtat aatcaagtta aaaaatagtt tttctattga
    12121 aaaaataaat aaaattctat tgtaatttaa tatgcgataa agttttataa aaaacaacat
    12181 taagctaggg ggacttattt tatggctttt aatatgaaat attttttaga attatttcca
    12241 acaataatga aatcgttcaa tgtaactgtg attttggcaa taagttcatt agtattttca
    12301 ttaattatag gtacaatagt agcgttatca tcttattaca aagtgaaagt attgaatcaa
    12361 atatgtaaag tatatgtatc tatttttaga ggtacacctc ttatgccaca gttattcttt
    12421 ttatattttg gactagcata tatgagtgat tttgttaaaa atatggaccc agtatttgca
    12481 acatctatag tacttagttt aaatatggga gcttatatgt ctgaaacgat aagggcatct
    12541 atactttcaa ttgatacagg tcagatagaa gcagcatatg caatgggatt aacaaattta
    12601 caaacaatga aaaggatagt gataccacag gccgtaagag ttgcactgcc atcattattc
    12661 aataatttta tagatttaat taaagggtct tctgtagctt ttgttgttgg agtaaatgat
    12721 ataatgggtg ctgccaaatt acaaggagcg ttgagtttta agttttttga agtgtatgga
    12781 gcagttatgg taatttactg gtgtataata actcctttag gttgggggca aaaaaaatta
    12841 gaaaagaaaa taagcaatta ttaagttatt aagaaaatac ataaaagtat ttttatataa
    12901 aaaatggtgt gaggagaaga gatatgataa aaagaaatat tataaaatgt ttagtggcag
    12961 ttttatcgtt aacgtttgta attactggtt gttcaaaaaa agaggaagta aagaatgaaa
    13021 aagttataac tgtagcttca tctaattcag ctgacccata ttcttatgtt gataatggtg
    13081 agcataaggg ttttgaagtt gacatgtgga aagagattgg taaaagaagt ggatataaga
    13141 taaaaatgga accaacaggt tttagttcta tatttggtat gttagattct ggtaaagttg
    13201 atgtggcagc caacttcttt ggaatgtcta aagaaagatt agaaaaatac gatgcttcta
    13261 taccttatgg ttctgattct gtgtgtatag ctgtaaaaga tggaaataac gaaattaata
    13321 agcttgaaga tttaaaggga aaagttgtag cagtttcaga aggttctcaa ggtcaacagg
    13381 ttgcaactag tgttaataaa gataatttgt ttcaagaaaa ggtttacggt gatggaacta
    13441 gtggtcttca agatttagat ttgggaagag ttagtgcatg gattgatgca gagcttacta
    13501 ttgtgggaga cgctaaaaaa gctaatatga aagtaagagt attagataaa aaattatcag
    13561 ctactaatat agcatacttc tttaagaaaa acgatgataa atctaaaacg ataaaagaag
    13621 atgtaaacaa agcaatagaa gaaatgcttg cagatggaac agtgaaaaaa atatctgaaa
    13681 aatggtttgg aatggatgta agtgctgata tacaaaaata aatactttaa aattaaaatg
    13741 taaaactgtg ataactatag ataagtatac taaatttatc tatagttatc tgtgtattac
    13801 aatgtattta gattagtctt tataaatcaa aatgagttat ggaggtattg caaatgattg
    13861 aaactaaaat aaaatccatt gcactaaaaa atagagaaaa aattataaaa ataagacgac
    13921 agatacacag taatccagag ttagcattta aagaatataa aacatctaaa cttataaaag
    13981 aagagctaaa taaacttaat atagaataca taaatattgc tggtacagga gtattagcta
    14041 ctataaaagg aaaaaataat ggtggaaaaa ctatattact cagagcggat atggatgctc
    14101 ttccaatcaa agaggaaaat gatttagaat ttaaatcaat aaatgataat atgcatgctt
    14161 gtgggcatga tgcacatgtt tcatggttgt taggaacagc aatgatttta aatgacataa
    14221 aagaagaatt gaatggaaat gtaaaattac tatttcaacc tggcgaagaa aaaggtggtt
    14281 ctgatattgt aattaaagaa aatgtacttg aaggtgtgga tgcattagcg actggtcatt
    14341 gttggccaac tattgagtca ggaaaaattg gaatcgctag aaattgtgct atggcagcga
    14401 ctaatacttt tgaaataaca ataattggca agggtgggca tggagcagag cctcataatt
    14461 gtatagaccc aattgcagtt ggaaatgcag tatattcatc cattcaacag atagtttcaa
    14521 gaaaaattga cccagttgta cctgtagtag tgtctgtttg ttcttttaat tctggtgttt
    14581 ctaaaaatat aataccagat gtatgtacac ttcaagggac tattagagcg ataagcaagg
    14641 aacaagtaat tgaagtaagt aaaattctag aatatatagt aaaaaatgta tgtaaagcac
    14701 atggagcaga ttgcaaattt gaaaagagta caggaggaga tgctgttata aatgacaaaa
    14761 acatgataga gataggaaga gaaagtgctt gcaaaatact tggagctgaa aatgttgaaa
    14821 taattgattt tcctgcaatg acaggtgagg attttgctat ttatatgaaa gaaaaacctg
    14881 gtttatttat gtatataggt gtaggagata aagaaaaaaa tataaattac agattgcata
    14941 gtaacaagtt taatatagat gaaaaatgtc ttagtatagc accttcatta ttttcacaac
    15001 ttacagtaga ttatttatgt caactataga gtacattcat aaaaatatat ttagcctatt
    15061 tttaaattta atgctagtat attaattttg atgtagaaca tattatttat tatatttatt
    15121 taaaaaggtg gataacaatg ataaaagtag aaaatttaca taaaagtttt aaagggacag
    15181 aagttcttaa aggtataaat ttagagataa gtcaaagtga agtagtagct atacttggat
    15241 catctggaac aggtaaatct acgttactta gatgtttaaa ttatttagtt gagcctacaa
    15301 aaggaaagat aatgattggt gatgtaaaag tagatgtaga aaaagcaaca aaaaaagata
    15361 taaccaattt aagaaaacat acatctatgg tgtttcaaaa ttataactta tttaaaaata
    15421 aaacagcatt agaaaatgta atggaggcat tgatagtagt tcataaaaag agtaagaaag
    15481 aagctagaga aatatcttta aaattaatag ataaagtagg tatgttggat aggaaagatt
    15541 tttatccatc aaagttgtct gggggacagc aacaaaggat aggtatagcg agagcgatgg
    15601 cagtaaatcc aaatgtaata ttatttgatg agcctacatc tgcacttgac ccagaacttg
    15661 ttggagaagt tttaagcgtt ataaaatctc ttgcaaaaga aggtataacg atgcttattg
    15721 taactcacga aataaatttt gcaaaagaag ttgctgataa aattatattt atggataatg
    15781 gtgtaatagc tgaagaagga actcctgatg aaatatttaa taatcctaaa aatgaaagaa
    15841 cagcaaaatt tttaaatatc attaggaaag aagaagtatt tagttaaaag tgtataaatt
    15901 aagcattaga agatatgtaa gataccccca ttaaatttat aagttagata ataaattt
//
LOCUS       DAMJXI010000079        15945 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.084, whole genome shotgun sequence.
ACCESSION   DAMJXI010000079 DAMJXI010000000
VERSION     DAMJXI010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15945
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.084"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            61..657
                     /locus_tag="PC465_003178"
     CDS             61..657
                     /locus_tag="PC465_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3793 family protein"
                     /protein_id="HDF2650459.1"
                     /translation="MSCCNSQFCCKNKIESSYIKWLLEVLGPVFLGSKPAEIINISFT
                     DVNREEKINDIYKYLYKCKKIDFIVIDKEKKGLKILFVNKKALSEKLKCKKTVNFLKF
                     LGYKQNTNVNAYLEHLVDKLKSDVFPDEIGIFLGYPLKDVIGFMGYSNYEVSMIKYWK
                     VYGDTKQSEDTYSKFLLHRKKMRKLLDYISVDKIVSCF"
     gene            complement(755..1714)
                     /locus_tag="PC465_003179"
     CDS             complement(755..1714)
                     /locus_tag="PC465_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2650460.1"
                     /translation="MTSLIMVLVGTVGCSTTNDKKDEPAKKEASLPKEINLTYVKSPL
                     NVPSILEKKDDLFGKEFKKDNIKVNFHELTTGPEQTQALAAGELDFLHALGGTSAIIA
                     ASNGVGLKITNIYSRSPKGYMLITNNDNIKSIKDLKGKKIVGPKGTILHQLLIAALAK
                     EGYTIDDVEYVNMDIPSAASALESKSADVAMLAGPVALKTINSGAKMIVNGEGLVSGI
                     IVTAVSDDFAEKYPELVKRFMKVHEETLKYMNENKDEVMDVVSKEVGLSLDETKEMYS
                     WYDFSSKITDKDIKELEDTQEFLMSNGMQQKKINIKDMLYNQN"
     gene            complement(1748..2479)
                     /locus_tag="PC465_003180"
     CDS             complement(1748..2479)
                     /locus_tag="PC465_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2650461.1"
                     /translation="MVRSGFLLENIYKKYLVDNKEHLVLDNISLNISSEEITVILGES
                     GCGKTTLLRILAGLENATSGNIYFFNNDKKCTPKVGMVFQESRLMPWLNVSENILLHT
                     EKDNRNKVDLDKYLKMMKLEKFKNSYPNELSGGMAHRVSIARALSFNPDILLMDEPFA
                     ALDYFTRRKMQKEVVNIHKNTKKGVVFVTHNIEEAMEIAKKIIVFSKNKRIKQFSVED
                     EYNRDLTKNYYINLKKEILRELGEF"
     gene            complement(2472..3242)
                     /locus_tag="PC465_003181"
     CDS             complement(2472..3242)
                     /locus_tag="PC465_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2650462.1"
                     /translation="MFEKIHKRLKGYYIFLIILILWKIVCVLGIWSSYILPPPEIVLD
                     TFIKMIYDGSIFLNVYASVRRILIGFLISSLMAIPLGVLFGVNKKMYEYFKPLFEFMR
                     STPPLALVPMLILWFGIGEESKIIIIILASFFPIFLNTLKGIKNCDNKLIEVGKSFNL
                     SKKRIFYKIIIPNSMLDIVVGLSLGLGYSFRAIIGAELIAASSGLGYLISDGKDMSRT
                     DVVLVGIFVIGFLGILSDYLFSKIITKFSKGKQVDLNG"
     gene            complement(3327..4037)
                     /locus_tag="PC465_003182"
     CDS             complement(3327..4037)
                     /locus_tag="PC465_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HDF2650463.1"
                     /translation="MFKFDVTNELMCIARGSGKFFAKKGAMVAFKGNFNFEKLLLGPS
                     NGGGLGRALLGHVQRSLTGEQMPIMVVEGEGEIYLAQNAYHVDVISIDPGDSIYVESE
                     NLLAFSEQLNYSVKLIGSGVISQKGLFTTHLVNKTGQNQDVAIITDGNPLILEGPCCV
                     DPDALVAWTGREPYPKVSKLSWKTFIGQTSGESYHMEFVEPGQIVIIQPSERLSGLKT
                     DSTPSDRMSSGGLRLGID"
     gene            complement(4217..4369)
                     /locus_tag="PC465_003183"
     CDS             complement(4217..4369)
                     /locus_tag="PC465_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HDF2650464.1"
                     /translation="MATFIIAAIVVVLMALAVMYMVKNSKKNGSSCGCGCSGCSSSKS
                     CHSAKR"
     gene            complement(4395..6551)
                     /gene="feoB"
                     /locus_tag="PC465_003184"
     CDS             complement(4395..6551)
                     /gene="feoB"
                     /locus_tag="PC465_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDF2650465.1"
                     /translation="MSIKIGLIGNPNCGKTTMFNGLTGSSQYVGNWPGVTVEKKGGKL
                     KGNKDVEIVDLPGIYSLSPYTLEEVVTRNFMLDDKPDAVINIVDASNIERNLYLTTQV
                     LELGIPTVIALNMMDIVNKNGDKINIKELSEVIGCPVVEVTAVKGQGIMEAAEKAVEL
                     ASSNNKLNFKLPFVDESKDAIEKIEKIIEEKTPYIDVETRWLAIKLFERDENVIQKLD
                     ISKTILNSIEEITRNCEDELDDDSESIITANRYEFISSIISSIIKKNRKGKETVSDKI
                     DKIVTNRILALPIFALIMWGVYYIAVSSLGTIATDWTNDVLFGEIIQGNVSNFLASLN
                     VAEWLQGLVVDGLIGGVGAVLGFVPQIMLLFLLLSILEDCGYMSRVAFIMDRIFRKFG
                     LSGKSFIPMLISSGCGVPGVMSTRTIENDRDRKMTIMLTTFIPCGAKIPIIALFAGAL
                     FGGASWVAPSMYFLGIAMIIICGIILKKTSLFAGEPSPFVMELPQYHIPSAKGVLIHM
                     WDRGKAFIIKAGTIIFVACGVIWFLQSFNWSLQMVDAGDSILASLGNIVAPIFAPLGF
                     GNWQSSVATVTGLVAKENVVGTFGVLFGISDATEQDPTLLASVASMFTVASAFAFMAF
                     NMLCAPCFAAIGAIKREMGSWKWTWITLGFQTLTAYIIALLINQVGSLVLGTGGSIAG
                     AIISIFIAVAVVFVVLTYSNKNMKKEKMGKLSYMKN"
     gene            complement(6651..6872)
                     /locus_tag="PC465_003185"
     CDS             complement(6651..6872)
                     /locus_tag="PC465_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2650466.1"
                     /translation="MNRLKDIKCGETVKVKKLEGEGATRRRIMDMGITRGVNIFIRKV
                     APLGDPIEVTVRDYELSIRKSDAEKIIVE"
     gene            complement(6885..7097)
                     /locus_tag="PC465_003186"
     CDS             complement(6885..7097)
                     /locus_tag="PC465_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2650467.1"
                     /translation="MMPLILSNTGEEVVIKKISGSDKTRTFLNSIGFVVGTNVKIVSK
                     IDGNLIIDVKDTRVALDKKMASRIII"
     gene            complement(7418..10315)
                     /locus_tag="PC465_003187"
     CDS             complement(7418..10315)
                     /locus_tag="PC465_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2650468.1"
                     /translation="MKAFKKHFLILSLIFLLIISCFNNILCFADESENSKKIRVGYCD
                     DYGIISSSKEHSYTGYGYDYLREISKYTRWEYEFVKGSWEECLDRLEKGEIDLLGPLQ
                     KNDERNKLFNFPKLSSGYEYSALYTKDSNNNMFYEDISSFKGMRVAVLRGNFHNTAFE
                     KYREENNFSVEYIYCNSIDELIESVNEKKADAFVCGSIINAKGMKIVSKFSVEPFYFA
                     TAKDKPNLVKELDYALKELKINDMYYELELYKKYFKREVNNSIAFTRQEMNFIKANPK
                     LTMVYDSEWSPVEYYDKESNSFKGISSDLMSIISKKCGIKFEYIKTKNYNESLDYIKS
                     GKATMLCGSINENDKAKRFNMKLTNPYINIPMIMVGKLDTNLNNDLNIALTSSYKSID
                     SYIEKSFENAKTTSYKSVESCLNAINEGKANLMILSSYQFDELLREGKSENLSVISVL
                     DTSYGMRIGVSNKTDPILVSILNKSIDKITEEELSDCIYSNTIDKPYKVPFGVIFKEY
                     SIQIISFVCILFLIAIKYIIYNKKKKEDYLRKIAYTDPLTEADSIDKFKINSNKLFAK
                     NNPEEYALFYIDVDKFKYINDMFGYDMGNDTLIHISNTIASELKEDEIFARVSADHFV
                     LLIKYKTDDDIKTRLNNIYNKVQILSNPKINYYKLILDCGIYKISKSDNDINTIMDRA
                     NTARKTIKGGHKNSFAFYDKEMHKKILKEKEIENSMVDALNNGEFIVYFQPKYSLSDY
                     QIIGAEALVRWDNPQKGLIPPIEFIPVFERNGFIVNIDFYVFEEVCKKIREWMDEGQK
                     VVPISVNLSRMHFVNSNFIEEFKLIVDKYKIPTRLIELELTETAVLDNIEGLLDTMNN
                     LKEKGFVISMDDFGTGYSSLNLLKELPVDILKLDRAFFTEKDESNNEKIVISNVIKMA
                     KELKMKVISEGVETISQVEFLKQIGCDMVQGYLFSKPMPVKEFEKIAFKKE"
     gene            complement(10642..11250)
                     /locus_tag="PC465_003188"
     CDS             complement(10642..11250)
                     /locus_tag="PC465_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HDF2650469.1"
                     /translation="MVDNLIKYIHKSDVAIVVLHEIYGINSFIEDVCQKYYKYGYDVF
                     CPELLGEKRVFPYSKVQEAYDFFINNVGFDIYKKVEKLINDLKSEYKYVFVAGYSVGA
                     TIAWRCSEDSFCDGIICCYGSRIRDYMDVIPKCPTLLVFAKHDSFDVDSISYQLSRKQ
                     NIQIEILDANHGFIDRYSNNYSDIQTKVFTIKEKSFLSKYLA"
     gene            complement(11510..12055)
                     /locus_tag="PC465_003189"
     CDS             complement(11510..12055)
                     /locus_tag="PC465_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HDF2650470.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEKNWADE
                     HRIGVAQGVDEEIIEGLRANFVGECTEVGMYLAMSRQADREGYPEVGEAYKRIALEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKKAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRYFGK"
     gene            complement(12173..13996)
                     /locus_tag="PC465_003190"
     CDS             complement(12173..13996)
                     /locus_tag="PC465_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2650471.1"
                     /translation="MNLSTGNQKVSRLKKKEKPKDFKKTFKRIFMYFKKDKKITRFIF
                     LLVIIDSIISTVIPYTIGKVVDIIDIDTYSKSIFLKGIIILLSFYIIEFSVKLSKGIC
                     TARLSQSIVREMRSNLFLKFKNLPITFFDKSSTGDIMSRVTNDVDNISTGISNSLVQL
                     ITGILNILMTFIMMFVLSPILTFCSVILIPIVMFVSNFIAKRTRVFFKQQQVELGKLN
                     AHIEEMISNINVVKSFNYERKSVNDFKEVNDRLLNISLKSQIYTSLLMPIMNVISNIG
                     FATICIIGGILASKDIITIGVIASFLSYVRQFTRPLNELANLFNTLLSAIAGCERVFE
                     IIDEQEEQEVHNMFKSEINDNKDGNLNSHFVKGEIELKDVSFSYDSKKKILDNINLKI
                     KSGTSNAIIGETGSGKTTIINLITNFYHIDEGSIFLDGKDIYSINRNYLRTCFGVVPQ
                     EGYIFNDTVMENIRYGNLEATDEEVIYASKIANAHKFIVKMREGYSTVLSDRGEDLSE
                     GQKQLISIARAVLKNAPILILDEATSNIDIATEAKIQEAINNLTYGKTSIIIAHRLST
                     ISNCDNIIVLENGRIVESGNHKELIKLKGHYYRNILLTQGK"
     gene            complement(14009..15784)
                     /locus_tag="PC465_003191"
     CDS             complement(14009..15784)
                     /locus_tag="PC465_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2650472.1"
                     /translation="MRYFKKYIKKYIVLFLTAVFFLTLEAFCDLAQPTIMAKIIDIGV
                     SNKNLDYILSTGAIMIGITFLGAIFAIIRSVISARVSQHFSYDLRQDVFEKINTYSLK
                     QIDKFGRASLITRITNDINQMQQFVNGMMRVFIKSPIMCIGSLIIAIKLNLKMSIIIL
                     IAVLIIFIIILLNMKIGYRLFKNVQESTDKVNSKLRQFLSGIKVVKLFCRYDYENQSF
                     EELNDELFKNSRKATTMMSFFRPTITIIINVSIIIILLIGRHLIYSGEIKIGIIVAYV
                     NYMTRILTSLIMISHVFNVFVRAKASYERISEVLVDENEEVIEREESLDVGEKDLKFV
                     NCDIIFENVDFSYNKNTDEKILKNVSFKIEEGQNIGVIGQTGSGKTSLVNLIQKLYII
                     DKGDIKIGGRSIYSISEESLRARIGVVFQNSSVFGKSILENVVMGNRDICKEDVVKSC
                     EIANANQFITKLENTYDEVLFQRGKNLSGGQRQRITIARAIAKKPQILILDDCFSAMD
                     INTETIIRKNIKEYISNLREKESKKCTVITISQKISSIIDCDKILVLDEGEVVGFATH
                     EDLLVSSPIYKKIFALQNLVSEDVN"
BASE COUNT         5292 a         2845 c         1567 g         6241 t
ORIGIN      
        1 tcattcatag tataatctaa ttacttgata ttaattttca tttgaaggag gttatctttt
       61 atgtcttgtt gtaattcaca attttgttgt aaaaataaaa ttgaatcatc atatataaaa
      121 tggcttttag aagttttagg tccagtcttt ttaggctcta aacctgctga aataataaat
      181 atttcgttta ctgatgtaaa tagagaggaa aaaattaatg atatttataa atatctatat
      241 aaatgtaaga aaatagattt tatagttatt gataaagaaa aaaagggatt aaaaatctta
      301 tttgtaaata aaaaagcatt atcagaaaaa ttaaaatgta aaaaaacagt aaacttttta
      361 aagtttttag gatacaaaca aaatacgaat gttaatgctt atttagagca tttagtagat
      421 aaacttaaga gtgatgtttt tcctgatgaa ataggtattt ttttaggata tcctcttaaa
      481 gatgtgattg gatttatggg atatagtaat tatgaagttt ctatgattaa atattggaaa
      541 gtttatggtg acacaaaaca atccgaggac acatattcga agtttttact tcaccgtaag
      601 aaaatgagaa aattactaga ctacataagt gtagataaaa tagtaagctg tttttaattg
      661 tgtttttgta taataataaa aatacaccct cttttaccat acagtttcca taataaataa
      721 gggtgtattt tccactttaa tattttaaag tattctaatt ttgattgtac aacatatctt
      781 taatatttat tttcttttgt tgcattccat tagacatcaa aaattcctgt gtatcttcta
      841 attcttttat atccttgtcc gttattttag aactaaagtc ataccaagaa tacatttctt
      901 ttgtttcatc taaagataaa ccaacttctt tagatacaac atccatcact tcatccttgt
      961 tttcattcat atattttaaa gtttcttcat gaaccttcat aaatcttttt actaattcag
     1021 gatatttttc agcaaagtca tcacttacag cagtaactat tattccactt actaatcctt
     1081 ctccatttac aatcattttg gcacctgaat ttatcgtttt caatgccact ggacctgcaa
     1141 gcattgctac atcagcactt ttactttcta atgcagaagc agcactagga atatccatat
     1201 ttacatattc aacatcatct atagtatagc cttctttagc aagtgcagca atcaacagtt
     1261 gatgaagtat agtccctttt ggacctacaa tttttttacc ttttaagtct tttatagatt
     1321 taatattatc attattagtt ataagcatat atccttttgg tgaacggcta taaatattcg
     1381 taattttaag accaacacca tttgatgcag ctattattgc agacgttcct cctaatgcat
     1441 gtaaaaagtc tagctcacct gctgctaatg cttgagtttg ctctggtcct gttgtcaatt
     1501 catggaaatt gacttttata ttgtcctttt taaattcctt tccaaataaa tcatcctttt
     1561 tttctaatat actaggaaca ttaagtggtg attttacata agttaaattt atttccttag
     1621 gtaaactagc ctcttttttt gcaggttcat ctttcttatc atttgttgtt gaacatccta
     1681 cagtcccaac caacaccatt attaaagatg tcattactgc taaaatcttt ttgtttcttt
     1741 taatcaatta aaactccccc aattccctta atatttcttt tttcaagttt atataatagt
     1801 ttttagttaa atctctatta tattcatctt cgacactaaa ttgtttaatc cttttatttt
     1861 tactaaaaac aattattttc tttgctattt ccatagcttc ttcaatattg tgagttacaa
     1921 atactacacc ttttttagta tttttatgga tatttacaac ttctttttgc atttttcttc
     1981 ttgtgaagta atctagtgct gcaaatggtt cgtccatcag caaaatatcg ggattgaagg
     2041 aaagtgctct tgctatactt actctgtgag ccattcctcc tgataattca tttggatatg
     2101 agtttttaaa cttttcaagc ttcatcattt ttaaatactt gtctaaatca actttatttc
     2161 tattatcttt ttcagtatgt aaaagtatat tttcacttac attcagccat ggcataagtc
     2221 tactttcttg aaataccatt cctacttttg gagtacactt tttatcatta ttaaaaaaat
     2281 atatgtttcc actagtagca ttttcaagcc ctgctaaaat tctaagtagc gttgttttcc
     2341 cacatccact ttcacctaat ataacagtta tctcttcact agatatattt aaagatatat
     2401 tatcaagaac taaatgctct ttattatcaa ctaaatattt cttatatata ttctctagca
     2461 aaaatccact tctaaccatt taaatcaacc tgcttccctt tgctaaattt tgttattatc
     2521 tttgaaaata gataatctga aagtatacct aaaaatccaa taacaaaaat tcctaccaat
     2581 acaacatcag ttctagacat atcttttcca tcagaaatca aatatcctag tcctgaagaa
     2641 gctgcaataa gctctgctcc aattatagcc ctaaaactat acccaagccc taaactaagt
     2701 ccaacaacaa tatccagcat agaattaggg attattattt tataaaaaat tctcttttta
     2761 gataaattaa aagatttacc tacttctatt aatttattgt cacaattttt tatacctttc
     2821 aatgtattta aaaatattgg aaaaaaggat gccaaaataa taattataat tttagattct
     2881 tcacctatac caaaccataa aataagcatt ggcaccaaag ctagtggagg tgtacttcgc
     2941 ataaattcaa atagtggttt gaaatattca tacatttttt tatttactcc aaataaaact
     3001 ccaagtggta tagccatcaa tgaacttatt aaaaaaccta ttaatatcct tcttacactg
     3061 gcataaacat ttaagaaaat agaaccgtca tatatcattt ttataaaagt atctaagact
     3121 atttcaggag gaggcagaat atagctactc catataccca aaacacatac tatcttccat
     3181 aaaattaaaa ttattaaaaa aatataatat cctttaagcc ttttatgaat tttctcaaac
     3241 atataaaact ccttttaaca tatctatccc tgctaccctt tttatttttt aatatcttaa
     3301 ataataatta agctatatca taagatttaa tctatgccaa gtcttaatcc acctgaactc
     3361 attctatcag aaggtgtaga atctgttttt aagccagaca atctttcaga tggttgtata
     3421 atgactattt gtccaggttc aacaaattcc atatgataag attctcctga agtctgacca
     3481 ataaaagtct tccatgatag ttttgatact ttaggatatg gttctcttcc agtccaagct
     3541 actaatgcat ctgggtcaac acaacaaggt ccttcaagaa ttagaggatt accatctgtt
     3601 attatagcaa catcttgatt ttgacctgtt ttatttacta aatgtgtagt aaaaagacct
     3661 ttttgagata ttacccctga accaatcaat tttacactgt aatttaattg ttcagaaaat
     3721 gccaataagt tttcactctc aacataaatg gaatcacctg ggtcaattga tattacatct
     3781 acatggtaag cattttgagc taggtaaatt tcaccttcac cttcaaccac cattattggc
     3841 atttgttctc ctgtcaatga cctctgaaca tgacctaata atgctcttcc caatccaccg
     3901 ccattacttg gacctaacag caatttttca aaattaaaat ttcctttaaa ggctaccata
     3961 gcaccttttt ttgcaaaaaa tttaccactt ccccttgcta tacacataag ctcgtttgta
     4021 acatcaaatt taaacataat attcacttat attgcttaat ttagcaataa tccctcctaa
     4081 tcatatattt atatataatt atacagtaaa attacagcat agtctaacct acttcaaata
     4141 tgaaatttgt tatttataca aaaaataaga acctgataat aaagcaattt aactttttat
     4201 caggctctta tcctatttat ctcttagcgc tatgacaact cttactactt gagcatccag
     4261 aacaaccaca tccacaactg ctaccattct tttttgaatt tttaaccata tacattacag
     4321 ctagtgccat taatactact acaatagctg ctataataaa tgtagccata ttcatcactc
     4381 cttatttata tgaattaatt tttcatataa cttaatttac ccattttttc ttttttcata
     4441 tttttatttg aataagttaa aactacaaag actactgcta ctgctataaa tatagatatt
     4501 attgccccag caatacttcc tccagtacct aaaactaaac ttccaacttg atttataaga
     4561 agagcaatta tatacgctgt taaagtttgg aatcctaatg taatccatgt ccatttccat
     4621 gaacccattt ctctttttat ggctccaata gctgcaaaac aaggtgcaca aagcatatta
     4681 aatgccataa atgcaaacgc actagctact gtaaacatgc ttgcaactga agcaagaagt
     4741 gttgggtctt gctctgttgc atctgatata ccaaataaaa ctccaaatgt tccaactaca
     4801 ttttccttag ctactagacc tgtaactgtt gctactgatg attgccaatt tccaaatcca
     4861 agaggagcaa atattggtgc aactatattt cctaagctag ctaatatact atctccagca
     4921 tctaccattt gtaatgacca attaaatgat tgtaagaacc agattactcc acaagcaaca
     4981 aatataattg ttcctgcttt gattataaat gcttttcctc tatcccacat atgtattaaa
     5041 acaccttttg cacttggaat atgatattga ggtaattcca taacaaatgg agatggttct
     5101 cctgcaaata aactagtttt ctttaatata attccacaaa tgattatcat tgcaatacct
     5161 aagaaataca ttgatggagc tacccatgaa gcacctccaa ataatgcccc tgcaaataat
     5221 gctattattg gaatcttagc tccacatgga atgaatgtag ttaacataat agtcattttt
     5281 ctatctctat cattctctat agtacgagtt gacataactc ctggaactcc acaacctgaa
     5341 cttataagca ttggtataaa tgattttcct gaaagaccaa acttacggaa aattctatcc
     5401 attataaaag ctacacgtga catgtaccca caatcttcta atattgataa taataagaat
     5461 aaaagcatga tttgtggtac aaatcctagt actgctccaa ctccaccaat tagaccatca
     5521 actacaagtc cttgtaacca ctctgctaca tttaaagaag ctagaaaatt acttacattg
     5581 ccttgaataa tttctccaaa cagtacatca tttgtccaat cagttgctat agtacccaat
     5641 gaacttactg ctatatagta aactccccac attataagtg caaaaatagg taatgctagt
     5701 atacgatttg ttacaatctt atctatctta tctgatacag tttccttacc ttttcgattc
     5761 ttctttatta tacttgaaat tattgaacta ataaattcat aacgattggc tgttattata
     5821 ctttcactat catcatccaa ttcatcttca caatttctag ttatttcttc aatactattc
     5881 aatattgttt tagaaatatc aagtttttgt ataacatttt catctctctc aaatagcttt
     5941 atagctaacc agcgtgtttc tacatctata tatggagtct tttcttctat tattttttca
     6001 attttttcta ttgcatcctt actttcatca acaaagggta atttgaaatt taatttattg
     6061 ttactacttg caagttcaac tgccttttca gcagcctcca taattccttg acctttaact
     6121 gctgttactt ctaccactgg gcaacctata acttcagata gttctttaat atttatctta
     6181 tcaccattct tatttacaat atccatcata ttaagagcta taacggtcgg tatacctagc
     6241 tctaaaactt gagttgtaag atataaattt ctctctatat ttgatgcatc tacaatattt
     6301 attactgcat ccggcttatc atctagcata aaattacgtg taactacttc ttctaatgta
     6361 tatggagata aagaataaat acctggtaaa tctactattt ccacatcttt atttcctttt
     6421 aattttccac cttttttttc aactgttact cctggccagt taccaacata ttgtgatgat
     6481 cctgtaagcc cattgaacat tgttgtctta ccacagttag gatttcctat gagacctatt
     6541 tttattgaca tttccattcc ctccattatt atttaaatac atcactgttt gtgatacaga
     6601 aaatcattct cattatataa ttacattaac cctactctaa ttaatcttta ttattccaca
     6661 ataatttttt ctgcatctga cttacgaatt gatagttcat aatctctgac tgttacctca
     6721 attgggtcac caagaggagc tacttttctt ataaatatat taacacctct tgtaatcccc
     6781 atatccatta tacgtcttcg tgtagctcct tctccctcta actttttgac ttttacagtc
     6841 tctccacact taatatcctt cagtctgttc atgtcattac ctccctatat tattattcta
     6901 cttgccattt ttttatctaa tgcaactcta gtatctttta cgtctattat taagttacca
     6961 tctatcttag aaactatttt aacatttgta cccactacaa aacctatact atttaaaaaa
     7021 gtcctcgtct tatcacttcc cgaaattttc tttataacta cttcttcacc tgtatttgat
     7081 aatatcaatg gcatcatata atatccctcc tcttaaagta atttaaatct acaagcaatc
     7141 gttatcttat atataaatta caatacctta aatcttaatc tattaaaata acatcctatt
     7201 ttttccttct ttttacaatt cctaattttg atttaagtct atcacaatag tatatttttt
     7261 gcaagtgatt attgtattct tttgattttt tttctcattt gatttatttt attaataaaa
     7321 tcgtaaaaat taatacaaaa ataaagatgc tctaaaatag tatactcaac taatattaaa
     7381 gcacctttat tatatatgtc attatttaca cattgcttta ttctttttta aaagcgattt
     7441 tttcaaactc ttttacaggc attggcttag aaaacaaata tccttgtacc atatcacacc
     7501 caatttgctt tagaaattct acttgcgaaa tagtctctac accttctgat attactttca
     7561 ttttcagttc ctttgccatt ttaatgacat tagatataac aattttttca ttattactct
     7621 catctttttc tgtaaaaaat gctctatcta gttttaatat gtcaacaggc aattctttta
     7681 aaagattaag agaggaatat cctgtaccaa aatcgtccat agagattaca aatccctttt
     7741 ctttcaaatt gttcattgta tcaagtaatc cttctatatt atctaatact gctgtttctg
     7801 ttagctctaa ttctataagt cttgtcggaa ttttgtattt atctacaatt aatttaaact
     7861 cctctataaa attactattt acaaaatgca ttcgagacaa gtttacagat ataggtacta
     7921 ctttttgtcc ttcatccatc cattctctaa tctttttaca cacttcctca aatacataga
     7981 aatcaatatt tacaataaaa ccattcctct caaatacagg aataaattct attggtggta
     8041 ttagaccttt ttgtggatta tcccaacgaa caagagcctc tgcccctata atttgataat
     8101 ctgaaaggct atatttaggt tgaaaataaa caataaattc tccattatta agagcatcta
     8161 ccattgaatt ttcaatttct ttctctttta atattttttt gtgcatttcc ttatcgtaaa
     8221 aagcaaatga atttttatga ccacctttta tagtttttct tgcagtatta gctctatcca
     8281 taatagtatt tatgtcatta tcacttttac ttattttata tataccacaa tctaaaatca
     8341 atttataata gtttatttta ggattactaa gtatttgaac cttattgtaa atattgttta
     8401 accttgtttt aatatcatca tctgtcttat acttaataag aagaacaaaa tggtcagcag
     8461 aaactcttgc aaaaatttca tcttccttta attcacttgc aatagtattt gatatatgta
     8521 tcaaagtatc atttcccata tcatatccaa acatatcatt tatatattta aatttgtcaa
     8581 catctatata aaacaacgca tattcttctg gattattctt agcaaacagt ttattagaat
     8641 ttattttaaa tttatctata ctatctgctt ctgtcaatgg gtctgtatat gctatcttcc
     8701 ttagataatc ctctttcttc tttttattat aaattatata tttaatagca attaagaata
     8761 aaatacatac aaaagaaata atttgtattg aatattcttt aaaaatcaca ccaaatggta
     8821 ctttataagg tttgtcaata gtattagaat atatacaatc acttaattct tcttcagtaa
     8881 ttttgtctat tgatttattt aaaatagaca ctaatatagg gtcagtttta tttgataccc
     8941 ctatacgcat cccatagctt gtatctaaaa cagatataac agataaattc tcactctttc
     9001 cttctcttaa aagttcatca aactgataag aactaagtat cattaagttt gctttacctt
     9061 catttatagc gtttagacaa ctttctacac tcttataaga tgttgtctta gcattttcaa
     9121 aactcttttc tatataagaa tcaatagact tataactact agttaaagca atatttaaat
     9181 cattattgag attggtatcc aattttccta ccataatcat tggaatattt atgtatggat
     9241 ttgtcaattt catattaaat cgttttgcct tatcattttc attgattgag ccacatagca
     9301 tagttgcctt accacttttt atgtaatcaa gactctcatt ataatttttt gttttaatat
     9361 attcaaattt tataccacat ttttttgata taattgacat taaatcggaa cttatacctt
     9421 taaatgaatt gctttcttta tcataatact ctacaggaga ccactctgaa tcatatacca
     9481 tagtaagttt tgggtttgct ttaataaaat tcatttcttg ccgagtaaat gctatggaat
     9541 tattgacctc tcttttgaaa tattttttat ataattccaa ctcataatac atatcattta
     9601 tttttaattc ttttaaagca taatctaatt cttttaccaa attaggttta tcttttgcag
     9661 tagcaaaata aaaaggttct actgaaaatt tgctaactat tttcattcct ttagcattta
     9721 taatacttcc acaaacaaat gcatctgcct ttttttcatt gacggactca attaattcat
     9781 caatagaatt acagtatata tattcaactg aaaaattatt ttcttctcta tacttctcaa
     9841 atgcagtatt atgaaagttt cctctaagta cagctactct cattccctta aaggaactta
     9901 tatcttcata aaacatatta ttgttactat cctttgtata tagtgcacta tattcatatc
     9961 ctgaacttag tttaggaaaa ttaaatagtt tatttctttc atcattcttc tgtaaaggtc
    10021 cgagtaagtc tatttcaccc ttttctagtc tgtctaaaca ttcttcccaa gaccctttta
    10081 caaattcata ttcccatctt gtatattttg agatttctct tagataatca taaccatatc
    10141 ctgtataaga atgctctttt gatgaggata ttattccgta gtcatcacaa tatccaactc
    10201 ttattttttt tgaattttca gactcatcag caaagcatag tatattgtta aaacatgata
    10261 taataagtaa aaatatcaaa gaaagtatca agaagtgctt tttaaatgct ttcatattta
    10321 aaaacctcca atttgccaac ttactttaac ttatttcgtt ttctagttgt aactactttt
    10381 attgtaatgg taaatatatc aaattgcaat attctcatat aatattctta ttcaactata
    10441 atgaatttat tattatctat ttaaatacac tatctaatat tagtttctta taagtcataa
    10501 aagcacaact aacactataa ttctagtgat taattttatt tcaaaaaata taataacact
    10561 actaatattt taaatatcaa tagtgtcata aaaacttttc agattaatta aatctttcta
    10621 tatattttat aataatctaa atcatgctaa atatttagac agaaaacttt tttctttaat
    10681 agtaaatact tttgtttgaa tatcagaata attatttgaa tatctatcta taaaaccatg
    10741 atttgcatct aaaatctcaa tttggatatt ttgtttccta gaaagttggt aagaaataga
    10801 atcaacatca aatgaatcgt gctttgcaaa tactaataag gtaggacatt ttggaattac
    10861 atccatgtaa tctctaatcc gagagccata acaacaaatt atgccatcac aaaaagaatc
    10921 ttcactgcat ctccatgcaa tagttgctcc cacgctatac ccagcaacaa atacatattt
    10981 atactctgat tttaaatcat ttataagctt ttcaactttt ttataaatat caaaaccaac
    11041 attatttata aaaaaatcat atgcctcttg gacttttgaa tatggaaaaa ctcttttttc
    11101 tcccagaagt tcaggacaaa atacatcata tccatattta taatactttt gacaaacatc
    11161 ttctataaag ctattaatcc catagatttc atgcaaaaca acaatagcta catcactttt
    11221 atgtatatac tttatcagat tatccaccac ctttacaaaa cagcaaattt tttatactta
    11281 gtttaatata ttcttcttta catgtcaatt tacttttcta aaatcaaatt tatttttgga
    11341 ttaatcattt atttttaaaa gttgtgcatt attactatta aattattctc tattattaaa
    11401 aatataatcg ttagaaataa aaaataaagt acaaataatt aaaaaatatc tcactcataa
    11461 ctttaaaaat tataagtgag atactcctaa aatctacttt atattaaatt tattttccaa
    11521 aatatctatt taataatcct aaaaatgctt taccatgtct agcttcatct ttacacattt
    11581 catgtactgt atcatgtata gcatctaatc ctaattcttt tgctttctta gctaatttta
    11641 attttccatc agttgcacca tactcagcat caactctaac tcttaagttt tcttttgtat
    11701 ctgcaactac aacttctcca agaagttctg caaatttagc agcatgttca gcttcttcaa
    11761 gagctattct cttataagct tctcctactt ctggataacc ttctctatca gcttgtctac
    11821 tcattgctaa atacattcct acttctgtac actcaccaac aaagttagct cttaatcctt
    11881 cgattatttc ttcatctaca ccttgagcta ctcctattct gtgctcatca gcccaatttt
    11941 tttcgccttt catttcttca aatttatcag ctccaacttt acatactgga cattgtgctg
    12001 gtgcagcatc tccttcatgt atatatccac atactgtaca aacaaatttc ttcataatta
    12061 ctttcctcct aaattttata tatcaaatta aattttttat ttattaagtt agtctatata
    12121 tacccgcacc atataccttt aaacaatttt tttaaaagtt ttttctaaat acttattttc
    12181 cctgtgtcaa taatatgttt ctataataat gtccctttaa ttttatcaat tctttatgat
    12241 ttcctgattc cacaattcta ccattttcta aaactattat attatcacaa tttgatatag
    12301 tacttaatct atgagctata attatacttg tctttccata agttaaatta tttattgctt
    12361 cttgaatttt agcttctgtt gctatatcta tgttacttgt agcctcatcc aaaataagta
    12421 ttggagcatt ttttaatact gctctagcaa tacttattaa ttgtttttga ccttcactta
    12481 aatcttcacc cctatccgat aatacagtac tatatccttc acgcatttta actataaatt
    12541 tatgtgcatt tgctatttta ctagcatata taacttcttc atcagtagcc tccagatttc
    12601 cataccttat attttccata actgtatcat tgaatatata accttcttgt ggaactactc
    12661 caaaacaagt tctcaaatag tttctgttaa tagagtatat atccttacca tctaaaaata
    12721 tacttccttc atctatatga taaaaatttg taattagatt tataatagtt gtttttccac
    12781 ttcccgtctc tcctatgatg gcatttgatg tgccagattt gatttttagg tttatattat
    12841 ctaaaatttt cttttttgaa tcataagaaa aacttacatc tttaagctca atttctccct
    12901 ttacaaaatg agagtttaaa ttaccatctt tattatcgtt aatctcactt ttaaacatgt
    12961 tatgcacttc ttgctcttct tgttcatcta taatttcaaa aactctttca catccagcta
    13021 tggctgaaag taatgtatta aatagatttg ctaattcatt taaaggtctt gtgaattgtc
    13081 ttacataact taaaaaacta gctataaccc ctatggttat aatatcttta gatgcaagaa
    13141 tgcctcctat aatacatata gttgcaaatc ctatattact aatcacattc ataataggca
    13201 ttaaaagaga agtgtaaatt tgcgatttaa gggaaatatt tagaagtcta tcattgactt
    13261 ctttaaaatc atttacagat tttctttcat aattaaaaga ttttactaca tttatgtttg
    13321 atatcatttc ttcaatatgt gcatttagtt ttcccaactc aacttgttgt tgcttaaaaa
    13381 aaactctagt tctctttgca ataaaattac tcacaaacat tactatcggt attaatatta
    13441 cactgcaaaa ggttaaaatt gggcttaata caaacatcat aataaaagtc atcaatatgt
    13501 ttaagattcc tgtaattaac tgtactaatg aatttgatat tcctgtactg atattatcga
    13561 catcatttgt cactctactc ataatatctc cagtagaact tttatcaaaa aaggttattg
    13621 gtagattttt aaattttaaa aataaattac ttctcatttc tctgactata ctttgagata
    13681 atctagctgt acatatcccc ttagacagtt taactgaaaa ctcaattata taaaatgaaa
    13741 gtaaaataat tattcctttt aagaaaatgg attttgaata agtatcgata tctattatgt
    13801 caactacctt tccaatagta tatggtatta cagttgatat aattgaatca attattacta
    13861 gcaaaaaaat aaatctagta atcttcttat cttttttaaa gtacataaaa attcttttaa
    13921 acgttttttt aaaatcttta ggcttttctt ttttctttaa tctactgacc ttctgatttc
    13981 cagtacttaa attcaatata cttcctcctt aatttacatc ttcacttact aaattttgca
    14041 acgcaaaaat ttttttataa attggagaac taaccagtaa atcttcatgt gtagcaaatc
    14101 caaccacctc accctcatcc aagactaaaa tcttatcaca gtcaattata gaactaatct
    14161 tttgtgaaat agttattaca gtacatttct tactttcctt ttctcttaaa ttacttatat
    14221 actcttttat attctttctt ataattgtct ctgtattaat atccattgca ctaaaacaat
    14281 catcaagaat taatatttgt ggttttttgg ctatagctct agctatagta attctttgtc
    14341 tctgtcctcc tgataaattt ttaccccttt ggaataaaac ttcatcataa gtattttcga
    14401 gttttgttat aaattgattt gcatttgcta tttcacatga ttttacaaca tcctctttgc
    14461 atatatctct atttcccata actacattct ccaatatact ttttccaaac acactactat
    14521 tttgaaatac tacacctatt cttgccctta aactttcttc agaaatactg tatatactac
    14581 gtcctccaat cttaatatca cctttatcaa ttatatataa tttttgaatt aaatttacta
    14641 aagaagtctt tcctgaacca gtttgaccaa tcacaccaat attttgacct tcttctattt
    14701 taaaggatac gttttttaat attttttcat ctgtattttt gttatacgaa aaatctacat
    14761 tttcaaaaat tatatcacag tttacaaact ttaaatcttt ttctccaaca tctaaacttt
    14821 cttctctctc aattacttct tcattctcat caaccaaaac ctcacttatt ctctcataag
    14881 atgcttttgc cctaacaaaa acattaaaaa catgtgaaat cattataaga gatgttaata
    14941 ttctagtcat atagtttaca taagcaacta taatcccaat tttaatttct cctgaataaa
    15001 ttaaatgcct tccaatcagt aatattatta ttatggaaac attaatgatt attgtaattg
    15061 tcggtctaaa aaatgacatc atagttgtag cttttctact atttttaaaa agttcatcat
    15121 ttaactcttc aaagctttgg ttctcataat cgtatctaca aaatagttta actactttta
    15181 ttccacttaa aaactgtctt aattttgaat ttactttatc tgtactttct tgtacatttt
    15241 taaataatct ataccctatc ttcatattaa gcaatattat aataaatata attaaaactg
    15301 caattagaat aattattgac atctttaaat ttaattttat agctataatt aaacttccta
    15361 tacacattat tggtgacttt ataaaaactc tcatcattcc attaacgaat tgttgcattt
    15421 gattgatatc attagtaatt cttgttatta atgaagctct accaaattta tctatttgtt
    15481 ttaatgagta tgtatttatc ttttcaaata catcctgtct taaatcataa gaaaaatgct
    15541 gagaaactct tgccgagatt acacttctta ttattgcaaa tattgcacct aaaaaagtta
    15601 tacctatcat tatagctcct gttgatagta tgtagtctaa gttcttattt gaaaccccta
    15661 tatctattat ttttgccatt atagttggtt gagctaaatc acaaaaagct tccaatgtta
    15721 aaaaaaatac tgctgttaga aataatacta tatatttttt tatgtatttt ttaaaatacc
    15781 tcattcaatc atcccttcat agaattttct cattaccaaa agtatatcat aatggctaat
    15841 ttaattgatt atatcaatta taaatatttg atttattatt aatttttata ccatatattt
    15901 tataaattat ttgtttttat ttcctatatt tatatatatt tatag
//
LOCUS       DAMJXI010000080        15792 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.085, whole genome shotgun sequence.
ACCESSION   DAMJXI010000080 DAMJXI010000000
VERSION     DAMJXI010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15792
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.085"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(91..378)
                     /locus_tag="PC465_003192"
     CDS             complement(91..378)
                     /locus_tag="PC465_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650473.1"
                     /translation="MRLNVTKQNTIEVENSRKEDVYFVIVDNVFFERQGDVFNSITNN
                     NLNNYDVKILPTDNVFLELKITSTKDLEPVFIVVEDRQYNHGSIMFKPVLV"
     gene            complement(398..673)
                     /locus_tag="PC465_003193"
     CDS             complement(398..673)
                     /locus_tag="PC465_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650474.1"
                     /translation="MSLFVGGWSKFRAVEEEDLKVFNEAVGMLEGVGYEPLIVSTQVV
                     AGTNFKFICNATSVTNPPQNYLAEIVVFKPLPCDEHNATITSINIIK"
     gene            complement(1310..1489)
                     /locus_tag="PC465_003194"
     CDS             complement(1310..1489)
                     /locus_tag="PC465_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650475.1"
                     /translation="MGKDRFEKVYSQGKINATEIWVDKETGVNYVFHYYGHAAGFTPL
                     LDREGKPVISPIVSK"
     gene            complement(1774..3240)
                     /locus_tag="PC465_003195"
     CDS             complement(1774..3240)
                     /locus_tag="PC465_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2650476.1"
                     /translation="MKRKPQYLIIFEHIIQQIYTGKITIGDRLDSIKSMSEEYMVSKN
                     TIKTVIKMLSEKGFIETKAGSRPVLIQSTSKQSIESDLLYEKILQISEIYKIFSLIFP
                     SIAMYNIKRFTSKDFEELNEIIDCMEKNSSNYLVFKEQRLKYINKLISKTNNFLIHHF
                     CEIIQHDVIISQLAYNFDNLDNCCIDFFRNKYIEQVRKTYLYGLDGNLIEFKKLLTYM
                     YKACRESILKMVENRAPQSIDTSSFNSVTLEKCYLYDLIVSDVICQIFEGNIKIGDCL
                     PSITSIINRYNVSLPTVRSAYNELNELGIAKTINGKGTYVTLFSEYDDDYINTEEGAK
                     RLSLLLDAMEFVTITLEDVVLLLGNKMDLIAVDKIETHLRYLQNNCEECKVYPDFVLL
                     CKIVDYTQIYVLQETFLHLKQYMIFGIYLERFFHEEYNEILKTRFDVCFEILRYLKKG
                     DVERFAESFSNIFKESLQYLKKVISSLNVDMRLKLGIL"
     gene            4228..5406
                     /locus_tag="PC465_003196"
     CDS             4228..5406
                     /locus_tag="PC465_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2650477.1"
                     /translation="MKYHIFLIITTILIIELCNIYICKIASFGNKNITIHKNYKYIFL
                     IKPLTFLIIIFTKLPLPLYYILFYIVSHKLLLSRKSSTNNHFIPNMAVISFCILHLIT
                     VSTISLVKNTSPDIIFANMTYRLISILIASILDFILWYSMNKIKEHIYIITQNQIEFS
                     LFLKFIWFTLGYILFDSIQITFAPPSSLTSYFILGSNILLILQLIIFINHIYSIEKNI
                     YLEKEHHRLKMIKQEQLLKVNLLKKKANIDELTSAYNRKFAFEKIQHYINNNLLFSLI
                     YIDLDKLKTINDTYGHLAGDNYIINFSSIVIENLGIDDIFARIGGDEFIVIMPKSNEN
                     TTKEFIEKISKIMDNTISFSYGIVEVSSENKMTVEEIINIADIRMYTNKQNNHKRNNN
                     "
     gene            5756..6637
                     /locus_tag="PC465_003197"
     CDS             5756..6637
                     /locus_tag="PC465_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2650478.1"
                     /translation="MPAYLFDSNSIANIYRVFPISFGFIVTGLYFSYKNNKNNKINFE
                     AVLEDKKNLIFLLSLMFGMYLYLCLSLSIYYTVGNVLILKLYGIKSAIIVLVGNYIAE
                     RYSFRITQIKGYDIKNQIEYVESIKTEYEINKLNDIVYTDLLTGFYNRPFVNQKLSEW
                     TSNHYKFTLCFTDLNSLKPVNDKFGHQFGDKYISTTAQIIKKLINVENSLLFRYGGDE
                     FLFLLQNTSCVEAEKIMININYELSKLSNTDEYPYALSISYGLVEWDGISDIETLISK
                     ADSLMYENKLKNKSTLN"
     gene            6828..6995
                     /locus_tag="PC465_003198"
                     /pseudo
     CDS             6828..6995
                     /locus_tag="PC465_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418025.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
     gene            complement(7255..9822)
                     /locus_tag="PC465_003199"
     CDS             complement(7255..9822)
                     /locus_tag="PC465_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HDF2650479.1"
                     /translation="MIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTA
                     SYQIFVETNHIQSRINKLLDGIDSNNTSQLEDVSKKIGELFHNGEMPQEVSDAIKTAY
                     AGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDKVIDAVKRCWASLWTARAIA
                     YRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSS
                     LVTPDTIVVDKDSERIISYEVANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQL
                     IQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEH
                     LPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSNP
                     LLIAIKSLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAHQIMEGIQTI
                     FYAACIYFTRIQLTLPAASISETLFTKLFQGAVRRAGITDTSVFLLGFDTIVLQSEKE
                     LWGISEWVKQNNSINLYLQNSPAIKIAEDFMSSVVPVGVSQEVWIEWKNRINKYFKEF
                     GRTAYEFDFAHSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHI
                     GGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDD
                     IYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAELKKYMGYVSPSKLPEKNKKTISQ
                     APQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS
                     SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRTIKSGQMITVDGLAGTVTFDE"
     gene            complement(9825..10430)
                     /locus_tag="PC465_003200"
     CDS             complement(9825..10430)
                     /locus_tag="PC465_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2650480.1"
                     /translation="MPKGIVLTPEQQAERREKIVAVALSLMAENGFQKTSMREIAVLA
                     NMGKSSLYDFFKTKDEIVVYAVEKEIEKTIQQVHRIIDGEPSPQQCLRKIMLNHLRFP
                     EQYRTVLMWLNTESDYLEEEYRKRLKDARYAYQDIIKSVIDNGVTTGIFRKTDTALVT
                     RLLINSMLSISYTSRPLDSSEKMLDETMNIFLHGIMNDGGE"
     gene            complement(10804..12264)
                     /locus_tag="PC465_003201"
     CDS             complement(10804..12264)
                     /locus_tag="PC465_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HDF2650481.1"
                     /translation="MFNELKTKENVYKNLINGKWVESNSRKPIEIYSPIDNSLVGKVQ
                     SMTKHEVDEVIKNTKESIKVWAEMPVYKRANIFHKAADLLLENIDEIANILVLEIAKD
                     IKSARAEVERTADFLRYTADVGKNMEGEAISGDNFPGGTRNKMSYVSRVPLGTVLAIS
                     PFNYPVNLSMSKIAPALIGGNAVVLKPATQGAISALHVVEIMRKAGIPDGVLNTITGR
                     GSEIGDYVVTHKGINFINFTGSTEVGQHISKISGMVPLLLELGGKDAAIVLEDADLDF
                     AAKNIVSGAYSYSGQRCTAVKRILVQESVADKLVGKIKPLVEKLTIGNPMDEVVITPL
                     IDNKATDFVQGLVDDALHKGAKLITGNVRKNNLFYPTLLDNVNVDMKIAWEEPFGPVL
                     PIIRVKDINQAIEIANQSEYGLQSSVFTSDIDKAFYIADKLEVGTVQINNKTERGPDH
                     FPFLGVKASGMGTQGVKYSIEAMTRPKAVVVNVREL"
     gene            12693..13271
                     /locus_tag="PC465_003202"
     CDS             12693..13271
                     /locus_tag="PC465_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2650482.1"
                     /translation="MAKSFTEIEKDNIRKRLISECEINWSKYGYKKTNIDELCSKSGI
                     AKGSFYTFFDSKEKLFFEVLNGIQNKLISSVDEILSNMPPKEGFAKSLKMLYRLYDKN
                     PFLYSPNNPDFISLINKLPQDMFLQLESNNIQSFYDLIERHNLKLKIEKEKVFGVCNA
                     LLSSLLVKENIEYNYIEVFDFMVDNLVEHILE"
     gene            13562..14812
                     /locus_tag="PC465_003203"
     CDS             13562..14812
                     /locus_tag="PC465_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2650483.1"
                     /translation="MVKSSNTFNKNFNLMILGQIISLFGASILKFALSLYILDITGKA
                     EIFATILAVSSIPIIVFSPIGGAIADIFNRRNLMVIFDFSSSLTVLILAVFLFNNNGS
                     ILLVGIIMTILSVISTMYQPTVQSSTPLLVDNEHLMNANGIVAGVASLTNIAGPVLGG
                     VLYGVIGINAIIVISCVSFFLSAIMEIFIQIPFIKQEQNSNIIKTIFTDIKDGIVHIC
                     KENRFILKILFLAIAINLFLSSMLIVGIPYIVKITMGASNFLYGLAEGAISFSSLVAA
                     VSIGIFSKHLKITNLHISFIICAVMFIPMAVSVYPFILNTGFPVPFLIFIVSSMLIFF
                     TTTLISIYVITVTQLKTPNELLGKVMSILFAGTAIAMPLGQVMYGKLFDLLSDRVYII
                     ILGVGFITLLIAFVSKITLRNENL"
     gene            14973..15542
                     /locus_tag="PC465_003204"
     CDS             14973..15542
                     /locus_tag="PC465_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDF2650484.1"
                     /translation="MSYMPTLEQAWEILRKYNKEEFHIRHAQIVSGVMRYYAKEYDPE
                     RVEFWEIVGLLHDLDFEMYPDEHCVKQRELMTELDLDKSIIDSTISHGYGLTGSDVKP
                     EQFMEKVLFAVDELTGLIGAAAIMRPSKSVSDLELKSVKKKFKDKSFAAGCSRDVIRS
                     GAEMLGWELDKLIQTTIEAMRSLIPEMAI"
BASE COUNT         5516 a         2574 c         2030 g         5672 t
ORIGIN      
        1 agttcaacta tactggttta aataggtttc ctttagttta aataattcac ctatacctac
       61 ttgaatagtt cacttttatt tgcttaaatt ctataccaat actggcttaa acattatact
      121 accatgattg tattgtctat cttcaactac aataaaaaca ggttctaaat ctttagtaga
      181 tgttattttt aattctaaaa aaacattatc agttggtaat atttttacat cataattatt
      241 taaattatta ttcgtgatac tattaaatac atcaccttga cgttcaaaaa aaacattatc
      301 aactattaca aaataaacat cttcttttct actattttca acctctatag tattttgttt
      361 agttacattt agtctcatct tccacctcct attaatatta cttaattata ttaatacttg
      421 taattgttgc attatgttca tcacaaggaa gaggtttaaa aacaactatc tctgctaaat
      481 aattctgtgg aggatttgta actgaagtag cattgcaaat aaatttaaaa tttgttcctg
      541 ctacaacttg agtagaaaca ataagtggtt cataaccaac cccttctaac attcctacag
      601 cttcattaaa tacttttaaa tcttcttctt cgacagctct gaattttgac catccaccaa
      661 caaaaagact catataaaaa cctcctttat atatatattt atttatatat atagtagtac
      721 caattttctc aatattcaat attttctgtg taactggtca atgaaaatgc ataactggat
      781 aaaaatactt ataaaataac ttaactttac atataaatag cttactttac atgtaataag
      841 attattctac aatatgaaat gcatcttgtt ttgaatatat tctaaataca ataatggata
      901 ttttcaatta ttataattag aaaatatcca ttacttaact tgttttattt aaaatcacat
      961 agagacttta ttattttttt tattgcatga atagctattt caggtatcat aagttgatat
     1021 accccctcct tgaaaccaca aaaaacataa caaactttac gaatcttgtc ttaaaagacc
     1081 acaggtacat tccttatttg tggattggag tagccataac aagcaaattt tacaattttt
     1141 atgatgacaa aaatcaataa aatcgcttag tatataacac gaaacactac ttgttactat
     1201 taagaatagt tagataggaa gtatgcatta taccaataaa ggaatcaata aagaaagtta
     1261 aaacatccct acaaatcaaa aatctgttac atttttctat atttaaacgt tatttactta
     1321 caattggaga aataacaggt tttccttctc ggtcaagtaa aggcgtaaat ccggctgcat
     1381 ggccataata gtggaataca tagttcacac ctgtttcttt atccacccaa atctccgttg
     1441 catttatttt tccttgtgaa tatacttttt caaatctatc ttttcccatt ttataatcct
     1501 ccatattttt gattggtcta tgccttcttc acttaagtag aaaaaataca taacttattt
     1561 ttttaattct aatatgagca cgtaaaaatg tcaaacagct tatttaattt cataacttca
     1621 tgttactgtt cgtaaccttg tctgtttact tacactgcat tacagcacca ttttatcctt
     1681 tacattattg tattgcacac agtaaaaatg cttactttat gggatttttc aactaaaaaa
     1741 aggattttat ctccacaaaa catttactat ttgttacaat atacctaatt ttaatctcat
     1801 atcaacattt aatgaagata taaccttttt caaatattgt aaagactcct taaaaatatt
     1861 agaaaaagat tctgcaaatc tctcaacatc tccttttttt aaatacctaa gtatctcaaa
     1921 acatacatca aaacgtgttt tcaaaatttc attatattct tcatgaaaaa atctctctaa
     1981 atagattcca aatatcatat attgttttaa atgcaaaaat gtttcctgta atacataaat
     2041 ttgtgtataa tctactatct tacaaagtaa aacaaaatct ggataaacct tacactcttc
     2101 acaattattt tgtaagtacc ttaaatgagt ttctatttta tctacagcta tcaaatccat
     2161 tttatttcct agtaaaagta ctacatcctc aagagtaatc gtaacaaact ccatagcatc
     2221 caaaagcaaa ctcaaccttt tagctccttc ttctgtattt atataatcat catcatattc
     2281 agaaaaaagt gttacatatg ttcccttgcc attaattgtt ttagcaattc ccaattcatt
     2341 tagctcatta taggcacttc taactgttgg aagagataca ttatatctat taattatcga
     2401 agtaattgat ggtagacaat ctcctatttt aatattgcct tcaaaaattt gacaaattac
     2461 atctgaaaca attaagtcat ataaataaca tttttccaac gttacagaat taaaactact
     2521 tgtatctata ctttgtggag cacgattttc taccatttta agtatggatt ctctacaagc
     2581 tttatacata tatgttaata gttttttaaa ttcaattaga ttcccgtcca atccatataa
     2641 gtaagttttt cttacctgct ctatgtattt attacgaaaa aagtctatac aacaattatc
     2701 caagttatcg aaattatagg ccaattgtga aataatgaca tcatgctgaa taatctcaca
     2761 aaaatggtga atcaggaaat tatttgtttt acttattagt ttatttatat attttagcct
     2821 ttgttcttta aagactaaat aattagaact atttttttcc atacaatcga taatctcgtt
     2881 taattcttca aagtctttag atgtaaatct tttaatattg tacatagcaa tagaaggaaa
     2941 tattaaacta aaaatcttat atatttctga tatttgtaaa atcttctcat ataataagtc
     3001 agattctatt gattgtttac tcgtactctg gattaaaact ggtctagaac cagcttttgt
     3061 ctctataaag cccttttctg agagcatttt tattacagtt tttatagtat tttttgatac
     3121 catatattct tctgacatgc tttttataga atcaagccta tctccaatag taattttacc
     3181 agtataaatt tgttgaatta tatgctcaaa aataattaaa tattgtggtt ttctcttcat
     3241 atttttcctc ttcgataaat tagatttatt gttttttgta aggtatattt acttttattt
     3301 aatagggcaa aatagttgct tattttttcc tcataatcta taattaatat aaaccattta
     3361 tatatatggt ctaagtttta taatactgta atgcagtaaa atagcatatt gtagctatac
     3421 tacagcaaat taacatacca ttgtagtata ttaattggaa taattttaag tacttcaaaa
     3481 ttccagcaaa acatatatgt gtttttgata ttatgtatat tcgttaatag aatagctata
     3541 cttgttttac ataataaatt atatgatact tgctatatgt aattactata tttaatacac
     3601 ataactatta tacttactat atgtaattac tatatttgat acacataatt attatactta
     3661 ctatatataa ttactatact tggacacata actattatac ttgctatatg taattactat
     3721 actttataca catagttatc atacatgcta tatataatta ctacacttgg acacataact
     3781 actatattta ctatatgtaa ttatactata cttggacata tagttatcat acatactata
     3841 tgtaattact atacttggac aaataattat tatatttgct atatgtaatt atactatact
     3901 tggacatata gttatcatac atactatata taattactat acttggacac atagttatca
     3961 tacatgctat atgtaattac tatacttata cacataacta ttatactttc catacataat
     4021 tactatattt ggacacatag ttatcataca tactgtatat taagatataa tactttttaa
     4081 attttatata acacagacac atgcaataaa aaagaaggta tccataataa gctctttgca
     4141 tgtacctaaa taaaaactgt aaaatagaat atataaaatc taatctattt taagtaaata
     4201 caatttcact ttaaaagagg atgtactatg aaataccata tatttttaat cataactact
     4261 atattaataa tcgaactatg taacatttac atatgcaaaa tagcatcttt tggaaacaaa
     4321 aatataacta tacataagaa ttacaaatat atttttttaa taaaaccatt aaccttcttg
     4381 ataataatat tcacaaaatt accattacca ctatattata tattgtttta catagtaagt
     4441 cataaattgc tcttaagcag aaaaagttct actaacaacc attttattcc caatatggca
     4501 gtaataagtt tttgtatttt acaccttatt actgtaagta caatatcact tgttaaaaat
     4561 acaagtccag atataatatt tgcaaatatg acctataggt taattagtat tttaatagct
     4621 tctattttag attttatctt atggtactct atgaataaaa taaaagagca tatttatata
     4681 ataactcaaa atcaaataga gttcagtcta tttttaaaat ttatctggtt cactttagga
     4741 tatatattat ttgatagtat acaaattaca tttgctccac caagttctct aacttcctac
     4801 tttatattgg gaagtaacat attattaatc ttacaactaa ttatattcat caatcatata
     4861 tattccattg aaaaaaatat ttatttagaa aaagaacatc atagactaaa aatgataaaa
     4921 caagaacaat tactaaaagt aaatttatta aagaaaaaag ctaacattga tgaattaaca
     4981 tcagcatata atcgaaaatt tgcttttgaa aaaatacagc attacattaa taacaattta
     5041 ttattttcat tgatatatat cgatttggat aaattaaaga cgataaatga tacatatgga
     5101 catttagctg gggataacta tattattaac ttctcaagta tagttattga aaacttagga
     5161 atagatgaca tatttgctag aataggagga gatgagttta tagttattat gcctaaatct
     5221 aatgaaaaca ccacaaaaga atttatagag aaaataagta aaattatgga taatacgata
     5281 tcttttagct atggtattgt agaagtttct agcgaaaaca aaatgactgt agaagaaatt
     5341 attaatattg ctgatattag aatgtacact aataaacaaa ataatcataa aaggaacaat
     5401 aactaaaatg aatatttaca tgagcttact tgtagtctca ctatgttttt tatcttatta
     5461 tctctatcat tataattttt ttaaatatct ggacataatg attaataact ctaaaaataa
     5521 atacacagta tatattatat attctatatt taattattta atttttatta tttgtactta
     5581 tttaaagttt catctaatta taaattggac aatttttatg ttgattttat tcatacaaat
     5641 taaagtaact tataaaatct ccacaataaa aaacattttt tattcactaa actgctccat
     5701 cattggttta gcaataaata tattttttag gtctttaatg tcaatagtgt taaatatgcc
     5761 agcatattta tttgatagta attctattgc aaatatttac agagtatttc ctatatcatt
     5821 tggctttata gttacaggac tatatttcag ttataaaaat aataaaaata ataagattaa
     5881 ctttgaggca gttttagagg acaaaaaaaa cttaattttc ttattgagcc ttatgtttgg
     5941 aatgtacttg tatctatgtt tgagtttgtc aatatactat actgttggaa atgtattgat
     6001 tttaaaatta tatggaatca agtctgccat aatagttttg gtaggtaact atattgcaga
     6061 aagatatagc tttagaatta ctcaaataaa aggttatgat attaaaaatc aaatagaata
     6121 tgtagaaagt ataaagacag agtatgaaat taataaattg aatgatattg tatatacaga
     6181 tttactgaca ggcttctaca atagaccttt tgtaaatcaa aaactatcag agtggacatc
     6241 aaatcactac aaatttacct tatgttttac tgatttaaat agcttaaaac ctgtaaatga
     6301 taaatttgga caccaatttg gtgataaata catatccact actgctcaaa taataaaaaa
     6361 acttataaat gtagaaaatt ccttactatt tagatatggt ggagatgaat ttttattcct
     6421 tttacagaat acaagttgtg tagaagcaga aaaaataatg attaatataa attatgaatt
     6481 atcaaaatta agtaatactg acgagtatcc ttatgctctt tccataagct atggattagt
     6541 tgagtgggat ggaatatccg atattgaaac tttaatatca aaggcagatt ctttgatgta
     6601 tgaaaataag cttaaaaata aatctacttt aaactagcta gttcagatat tctacaaaat
     6661 atatgttata agagagtact aagaatgtca aaatatatag attttgcaaa tattgaatac
     6721 agtttactaa tgaatgcact ggatgtaagt gttagtaaac acctattaga tgaacacttt
     6781 actgttgttt gggctaatga ccattattat gaaatgttcg gctataccta gctaaaaagt
     6841 taaaaatgac cactgtagcc gagggaatag agaccagttt tcaaaaagat ttcttacaag
     6901 aaatagactg tgatatgtta caaggatacg tgttctctag acctttacca ataaaagact
     6961 ttgaaaaact tatgtttcaa aactcctcca attaacaata taaaattgct tattataagt
     7021 gatattattg tatcaacaaa taaaggaatt gtctcaaaat tgattttttc taatcaaatt
     7081 tttattttga gacattctca tttttttgca taagaaaata cccaccaagc tacggttttt
     7141 cttaccgctg ttcggtgggt attagtagta ttatgaaatc tgaaaacttt aagtattact
     7201 acttccgcta gcgcaatcac aaaggtcgaa agcttcaaag cgaaaatagg ctttttactc
     7261 atcaaacgtc accgtacctg ccaacccatc caccgttatc atttgtccgc tcttaatagt
     7321 tcgtgtggca atgtgtgtag ccataacggc tgggatgcca tattcacgtg cgacaatgct
     7381 tgaatggcta agaggaccac caatgtccgt tacaatcgca cttgcagatg aaaataatgg
     7441 tgtccatgct ggagttgtgg taactgcaac caaaacactt ccaggttgaa agctttcaaa
     7501 atctgctgga ctattcagta cacaagctgg agccgtcaca acaccagtac tggtaccaat
     7561 gcccgtcaac acaattttcc catctttctg cttctgtggt gcttgtgata tagttttttt
     7621 gtttttttct ggcaacttgg atggtgacac ataacccatg tattttttaa gttcagcttt
     7681 tcgaacaggt attatcccgt tcatatcaga tagagacttg tttttatcca actgctctat
     7741 aagtacctcc aattccgatt ttgtgagcca ataaatatca tctaaatgtg aaatagctcc
     7801 tcctcgtatg aatcgttctg agatttcctg aaacatacaa cgaatcagag gatgtcccat
     7861 tcccatcaaa taaatagcat tttcacgcat aggagaggtt tcctgtgccc aatggagcaa
     7921 cttaaaaaat agttttttac gcaatccacc tatgtgttgt aaaatctctt cttctgcatg
     7981 ttttctacgc ttttcaaacg tggtctggcg taaaaaagga ctttcccctt ttccttccac
     8041 aaatgttttt acggattcaa aagttggtgt aagtgtttcc tgcggtgtgg aatgcgcaaa
     8101 atcaaactca taagcggtac gaccaaactc tttaaagtac ttattgattc gatttttcca
     8161 ttctatccat acttcctgtg aaactccaac aggcacaact gaagacatga aatcttctgc
     8221 tatctttatt gcaggactgt tttgcagata aaggttgatg ctgttatttt gctttaccca
     8281 ttctgaaata ccccacaact ccttttccga ttgcagaaca atcgtatcaa acccaagcag
     8341 gaaaacggaa gtatccgtta taccagcacg tcgaactgct ccttgaaata attttgtaaa
     8401 taatgtttca ctgatagaag cagcaggcaa tgtaagctga atccttgtga aataaataca
     8461 tgcggcataa aatattgtct gaataccctc cataatttga tgggcgttca tagtatgcag
     8521 gggcttttct tcccattgtt taatagcatc ctcatatcct tttcgtgccg tttcccagcg
     8581 tgcaacgctg ttcataagtg tcctacgtaa agagcgtggg gaaagggatt tgatagcaat
     8641 caaaagtgga tttgatttag cagaaagata aacatatcca ttaataaccg tatatgcccc
     8701 gttttttggt aataattttt tcgcactttt accaaacata tctatccata aaagctctga
     8761 tgcacggttt acgatttcaa gaccaagcgt ggcgaacaaa ggtgtaacag gatttggcaa
     8821 atgttctgcc aaacttccct ttgtgtatac aacatcctgt tctggcaata cccattctgg
     8881 tggcagaaca gtaattggac gagcctgaac aatgtacaat ttatcttttt ccagtgccca
     8941 ctctacatcc ataggcattt gataatactt ctcaattttc tttccaagct gtatcagttg
     9001 cattacctga ttacgagtaa gagcatattt ttttctcaac ctttcaggaa ccatggtttc
     9061 ttctgttcct tctgaagtac gaaccgtcat aatctcttta tttgccactt catacgatat
     9121 aattcgttcg gaatccttat ccactacgat tgtatcgggt gtaactaagc tagaaaccac
     9181 cgcttcacca agcccccatg cagcgttaat aatcatttcg ctacgtctac cattgattgg
     9241 gtttaacgta aacataatac cagatgaatc ggaaaatgca agcttttgta ctacaacagc
     9301 aagtgcgaca atctcgtgct ttatattatt cttcacacga taagcaatag cacgagctgt
     9361 ccataaggaa gcccagcatc tctttacagc gtcaataact ttatcttcac cttgtatgtt
     9421 aagataagtt tcctgctgac ctgcaaaaga agcgtcaggt aaatcttcag cagtcgcaga
     9481 cgaacggaca gccaccgata tgttccctaa tccggcataa gctgttttaa ttgcgtccga
     9541 cacttcctgt ggcatttctc cattatggaa aagctcccct attttcttag atacatcttc
     9601 aagttggctg gtattattgg aatcaatacc atctagcagt ttattaattc gagactgaat
     9661 atggttcgtc tcaacaaaaa tctggtatga agcagtcgta acatgaaaac cgtctggcac
     9721 agggatgcct gctgtcaata gttttgataa agacatccct tttccaccaa caatttcaat
     9781 ggttgcttgt ttatgttcca gtggcaagac ataataaatc ataatcattc acctccatca
     9841 ttcataattc cgtgcagaaa tatattcatt gtttcatcca acattttttc cgaactatcc
     9901 aatggtcttg acgtgtaact gattgataac atggagttaa ttaacaaacg tgtcacaaga
     9961 gcggtatccg ttttgcgaaa gatgcctgtg gtcacaccat tatcaattac cgattttata
    10021 atatcttgat atgcataacg agcatcttta agtctctttc gatactcttc ttctaaataa
    10081 tcagattctg tatttaacca catcagtaca gttctatact gctctggaaa tctaagatga
    10141 ttaagcatga tttttctaag gcactgttgt ggtgaaggtt caccatcaat aatcctatga
    10201 acttgttgga tagttttttc tatttctttc tcaactgcat atacaacaat ctcatctttc
    10261 gttttgaaaa aatcgtatag acttgacttt cccatgttgg ctaaaactgc aatttctctc
    10321 attgatgttt tttggaatcc attttcagcc atgagactca aagcaacagc aactattttt
    10381 tctcggcgtt ctgcttgttg ttcgggtgta agcacaattc cttttggcat agggcgatac
    10441 ctccttttag cgaccactgg tcgtttcttt tttatttatc atacagcgac caacggtcac
    10501 ttgtcaaggt taattttttt cattgtatat ggtactcgag ataaaaatgt tcattttaga
    10561 aattgctcta tttaagtaga aataggcttc atcattagaa aacaagacta taaatttgag
    10621 atatttatca tgttcaaatt tcatcaatat caaagtttaa aatattaata aaaaaagaat
    10681 tactaagaaa taacatataa agattcaaaa aaggagttga acttaaaatt taattacaaa
    10741 aaatcaaatt taagacaact cctttattct ttatctctac tattctttat ctctatttat
    10801 ttattacaac tccctaacat ttaccactac tgccttaggt ctagtcatag cctcaattga
    10861 atacttaaca ccttgagttc ccataccaga tgcctttaca cctaaaaatg ggaagtggtc
    10921 tggacctctt tcagtcttat tatttatttg aacagtacca acttcaagtt tatcagctat
    10981 ataaaatgcc ttatcaatat cacttgtaaa tactgatgat tgaagcccat actctgattg
    11041 attagcaatt tcaattgctt gatttatatc tttaactctt ataattggaa gtactggacc
    11101 aaatggttct tcccaagcaa ttttcatatc aacatttaca ttatctaaca atgttggata
    11161 gaataaatta ttttttctaa cattgcctgt tattaacttt gctcctttat gtaatgcatc
    11221 atcaaccaac ccttgaacaa aatcagttgc tttattatct ataagaggag tgataactac
    11281 ttcatccatt ggatttccaa ttgtcaactt ctctaccaat ggctttattt ttccgactaa
    11341 tttatccgcc acactctctt gtactaaaat tctctttact gccgtacatc tttgtcctga
    11401 atatgaatac gctccagata ctatattctt agctgcaaaa tctaagtctg catcttctaa
    11461 tactatagcc gcatcttttc caccaagctc caataataat ggtaccattc cagatatttt
    11521 agatatatgc tgaccaactt cagtactacc agtaaagtta ataaaattaa ttcctttatg
    11581 cgttacaaca taatctccta tctcactacc cctacctgta atagtattaa gtactccatc
    11641 tggtatccca gcttttctca taatttctac cacatgaagt gcgctaatag ccccttgtgt
    11701 agcaggtttt aatacgactg catttccacc aataagtgct ggagcaatct ttgacattga
    11761 taaatttaca ggataattaa aaggagatat agctaaaaca gtacctaatg gaacccttga
    11821 aacataagac atcttatttc ttgttccacc agggaaatta tctccactaa tggcttcacc
    11881 ctccatattt tttcccacat cagctgtgta tcttaaaaaa tctgctgttc tctcaacttc
    11941 tgcccttgca gattttatgt ctttggctat ttcaagtacc agtatattag ctatctcatc
    12001 tatattttct aacaataaat cagcagcctt atgaaatata ttggctctct tgtatacagg
    12061 catttcagcc catactttta tactctcttt tgtgtttttt ataacctcat ctacctcatg
    12121 ttttgtcata gattgtactt tcccaacaag agaattatct attggtgagt aaatttctat
    12181 tggctttctc gaattagatt ctacccattt tccatttatt aaatttttat atacattttc
    12241 ttttgtttta agttcattaa acatattttt attcctctct ctgatataac tttgtgtatt
    12301 taaattatag ccatttattc gttatgtaaa catttctttt ttccataaac gtttacctat
    12361 aaaaaaaatt ttaagttaac gtttttctac attcttctat tttaataaca tactcgctcc
    12421 aaatctatat aggtcacact ttaatatcaa tatactaata taccaatata ctaatatact
    12481 aatataccaa tatactaata tactaatata ctaatatact aatataccaa tataccaata
    12541 taccaatata ccaatatacc aatataccaa tataccaata ttataaacat aaatcacttg
    12601 acaaatttat aagtagacaa tattatatat ctatgactca aaatattttc aaagtcatat
    12661 atatcatata tagacagaaa ggattgataa aaatggctaa aagttttaca gaaatagaaa
    12721 aagacaatat aagaaaaaga ctaatttcag aatgtgaaat caactggtct aaatatggat
    12781 acaaaaaaac taatattgat gaactttgtt caaaatcagg aattgcaaag ggttctttct
    12841 atacattttt tgattcaaaa gaaaagttat tttttgaagt attaaatgga atccaaaaca
    12901 aacttatatc atcagtagat gaaattttaa gtaacatgcc tccaaaagaa ggctttgcaa
    12961 aatccttaaa aatgttatat cgattatatg ataaaaatcc atttttatat tcaccaaata
    13021 atcctgattt catcagccta ataaataaac tacctcaaga tatgttttta caacttgagt
    13081 ccaataacat acaaagtttt tacgacttaa ttgagagaca caatctcaag ttgaagatag
    13141 aaaaagaaaa agtttttggt gtttgtaatg ctctactatc aagtctattg gtaaaagaaa
    13201 atattgaata taactatatt gaagtgtttg actttatggt ggataatctt gtagaacaca
    13261 tacttgaata acaatttaaa ataatttttc taagtatttt tttatactaa ataggattaa
    13321 tatgattgaa ttaatgaaaa aaataaacaa tataatttat aaaataaatg ataaactaaa
    13381 tatcacacaa aacttataga ccctagagca aacccattcc actctactct aagccatcta
    13441 taatagtttg tatatttcta ataatattag atattaaagt aagaaaaaaa ttccttataa
    13501 taattgctat tatatcaatt attataaata ttttaataat cttagatagg taggtacata
    13561 tatggtaaaa tcctcgaaca cttttaataa aaacttcaac ttgatgatat taggtcaaat
    13621 aatctcattg tttggtgcat caatactcaa gtttgctttg tctttataca tacttgatat
    13681 aactggtaaa gcagaaatat ttgctactat actagcagta tcttcaatcc caattatagt
    13741 attctcccct attggtggag ctattgcgga tatattcaac agaagaaact taatggttat
    13801 ttttgatttt tcaagtagtc ttacagtact aatcttagca gtattcttat tcaacaataa
    13861 tggttcaata ttacttgtag gaattattat gaccatatta tcagtcataa gcacaatgta
    13921 tcaaccaact gttcagtcaa gtacacccct tttagttgat aatgagcatt taatgaatgc
    13981 aaatggtatt gtagctggag ttgcatctct tacaaatatt gcaggacctg tattaggagg
    14041 tgtcttgtat ggtgtgattg gaattaatgc aattatagtt ataagttgtg taagtttctt
    14101 tctatctgca attatggaga tatttataca gattcctttt atcaaacaag agcaaaacag
    14161 caacattata aaaactatat ttactgatat aaaggatggt attgttcata tatgtaaaga
    14221 aaatagattt atactaaaaa tacttttttt agctatagca ataaacttat ttttaagctc
    14281 tatgttaata gttggtatcc cctatatagt aaaaatcact atgggagcta gtaacttctt
    14341 atatggtcta gcagaaggag caatttcttt tagttcactg gtagctgctg ttagtattgg
    14401 tattttctca aaacatctaa aaatcactaa tttgcacatt tcctttatta tatgtgcagt
    14461 tatgttcata ccaatggcgg tttcagtata tccatttata ttaaacacag gatttccagt
    14521 tccattttta atctttatag tatcatctat gctaatattt tttacaacga ctcttatctc
    14581 aatatatgtt ataacagtca cacaattaaa aactccaaat gaactcttag gaaaagtaat
    14641 gtcaattctt tttgcaggaa cagcaattgc aatgcccctt ggtcaggtta tgtatggtaa
    14701 actttttgat ttattatcag atagagtgta catcattata ctaggagttg gatttattac
    14761 attacttata gcatttgtat caaagataac attgaggaac gaaaatcttt agatacaaag
    14821 aatttagata taaagattta attttcacta atttctgaat ttaaatgcaa aattgtgtat
    14881 cagtatgttg acgttttaga aattgattga tataatcaat ggaaaataaa ctttataaaa
    14941 attcaaaata ttcagctaga ggagtgataa aaatgagtta catgccaact ttagaacaag
    15001 catgggaaat attaagaaaa tacaataagg aagaatttca tataagacat gctcaaattg
    15061 tatctggagt tatgagatac tatgcaaagg agtacgaccc tgaaagagta gaattttggg
    15121 aaatagttgg acttttacat gatttagatt ttgaaatgta tcctgatgaa cattgtgtta
    15181 aacaaagaga attaatgaca gagcttgatt tagataaatc aataatcgat tctacaataa
    15241 gtcatggata tggattaact ggttcagatg ttaaaccaga gcaatttatg gagaaagtat
    15301 tatttgctgt ggatgaactt actggtttaa ttggtgctgc tgcaataatg cgtccttcaa
    15361 agagcgtttc tgatttagaa ttaaaatctg ttaagaagaa atttaaagat aaatcatttg
    15421 ctgctggctg ttctcgagac gttataagaa gtggtgcaga aatgcttgga tgggaacttg
    15481 ataagcttat ccaaacaact atagaagcta tgagaagctt gattccagag atggcaatat
    15541 agctcctcca tacatatacc atagaagtta catctttaaa gagcatttct ctttttgatg
    15601 caacttcttt ttatattttg tagaataaaa agtttaatat tttaaactca ctatataatc
    15661 tataataaat actataaata atataatgta taatagttat aaactttcta accttaaaag
    15721 tttctaatac tcaataaaca attctaatat acaaatgtca ttatatgatt taattatata
    15781 tcttcaatat at
//
LOCUS       DAMJXI010000081        15587 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.086, whole genome shotgun sequence.
ACCESSION   DAMJXI010000081 DAMJXI010000000
VERSION     DAMJXI010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15587
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.086"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            122..1513
                     /locus_tag="PC465_003205"
     CDS             122..1513
                     /locus_tag="PC465_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDF2650485.1"
                     /translation="MSSTESVSKKSGHPKSFWLICMTILWERFSYYGLTALLVLFFTA
                     SVAQGGLGLSTQEATSMFGLFTGLIYLTPLVGGWLADKVLGQQKCISIGALLIAIGDF
                     VLFASSTSIAMVWVGLSIIILGNGFFKSSCSNIVGDIYPKTDVSRKDAAYSLFYMAVN
                     VGAFIAPIICGLLSDNVFAVRGASGDIVSYGYKMAFLICGIGMMLGMIIFTLLAPKLL
                     NEVGKYPVTKGNKGEKIEYGPLTKLEKNRIIAMVILFLFVVLFWTAYYQTQSSFMIYV
                     RDNVNRTLFGFEMPVAWLTSLNAILCVALCPVLATLWVKLSHTKRGDFSIPVKMGLGM
                     IIMGVGFIVMVFATLANGPDGMVKASILFIVLTYIFTTVGELFLSPIGLAMFNKLAPA
                     KYATLSMGAWYLTSFFASLLSGKIAGFTATLGFLQIFGGIATVLIIFGLILLGIRNVL
                     TRLMAMDLLTKEK"
     gene            1766..3559
                     /locus_tag="PC465_003206"
     CDS             1766..3559
                     /locus_tag="PC465_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2650486.1"
                     /translation="MNIKDRLSGLRKFMEEKNIDAYMIPSSDNHQSEYVGDYFKSREF
                     ISGFNGSAGTVIVTKDEAGLWTDGRYFIQAESQLEGSTIKLFKMGQEGCPTTDEYLYK
                     NIPEGGTLGFDGRVISAREGATLAEKLSKKGIKIEYQYDLIDSIWPDRPALSDSKAFL
                     LDVKYCGESFSSKLARLREKMSEKGTSTHVITTLDDIAWLFNIRGGDVKYNPVVLSYA
                     VITLKEVYLFVDESKLNEEILNELAKENVQIKPYNDVYEFVKNIDKTEKVLLDGTKLS
                     YTIYNNIPCEVEKVDEFNPVMFFKAQKNEVELENIRNSHVKDGVAFTKFMYWLKKNVG
                     KMEITEISATQKLEDLRREQEGFFEPSFNTIAAYKEHAAMMHYSATPESNYKLEAEGL
                     FLVDSGGQYYDGTTDITRTTVLGPISDELKLHFTSVARGMINLSKAKFLHGCRGYNLD
                     ILSRSCMWNMGIDYQCGTGHGIGFVLNVHEAPNGFRWRVVPERFDSAVLEEGMVTTNE
                     PGIYIEGSHGIRTENEIVVRKAEKNFYGQFMEFEVVTLAPIDLDGIVPELMNKDEKDY
                     LNWYHKLVYDKISPFLTDEEREWLKVYTRAI"
     gene            complement(3640..5022)
                     /locus_tag="PC465_003207"
     CDS             complement(3640..5022)
                     /locus_tag="PC465_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDF2650487.1"
                     /translation="MSVLKTQEKLKQPRDLYFCCSIFTFVGLAYYGMKLVLLLFLAEQ
                     VSKGGLGLTPAESASMLASFLAWTYFSPVIGGWVSDRFLGPKNCIILGMLMVSIGYFL
                     GYIANSKMDINIMIFLSGLGIGFYKGNLHTMVGNLYTNDDPRKDGAFSITYMATNLGT
                     LFGPLICGLVANEWFAMKSGLSISMYGYRYVFLFSSITVLIGLFFFIFGNRKFYKPLN
                     NDPINGRESIRKSLEYKKMLASRPLTLIEKKRIIVILVLAFFTVFFWIAYNQASMSIA
                     LYTKEHINLTVGNFQIPTSWIDSYNGLLCVILGPISALVWVKLSQTKKGDLSVPKKMS
                     LGFILLAIAFLFMIVAVIQTGTDPNSIHKASVFWVVGFLTFQSIGEICFSPVGYGMVN
                     KLSPEKYISLLMGVWFLGKFAANKLSGYTQAIIDQLGMLQVFIVIPSFLLIFGIILLI
                     MNKKLVELSN"
     gene            5280..5627
                     /locus_tag="PC465_003208"
     CDS             5280..5627
                     /locus_tag="PC465_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDF2650488.1"
                     /translation="MIRKKSELQVEVKENLNGGIGKVKLENIIQNEELKGKGRLFKRV
                     ALPVGSSIGVHDHTTDFEVYYILKGKGKVFDNGEFVEVNEGDVVYTADGEKHSIENIG
                     EEDLEFVALVLYM"
     gene            5645..6679
                     /locus_tag="PC465_003209"
     CDS             5645..6679
                     /locus_tag="PC465_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650489.1"
                     /translation="MTGKIEEIKDKINRFCNSNLNQEYKDISFKILQNLLDNNKEIIH
                     SSRADIWSSAILNIVLEQNLLYNKKHPLHITKKEFSKQIGVSLNTINNKSSLIKDVCS
                     IDFLNQDTIAISNVEFWVKETNSKSKSVDLDLEKKKILYKRYIKLSQDANSDIESIRY
                     MEEAVNIGKSMITKEDKELGFWKGLSTRAYMIALESLARKLESINNLKESKKVLEYLI
                     EINPSDEQGIRYKLLNVLIRLNDRTSINKLFELYKEEKSATWMYSKALYYFKNKSMFL
                     ANDSIKVARSKNKYVGLYLLDWRNAFGREFVTEEEKAEAVYYYDENIVIWNEVKGSMD
                     WLLKKMLEFS"
     gene            complement(6728..7777)
                     /locus_tag="PC465_003210"
     CDS             complement(6728..7777)
                     /locus_tag="PC465_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2650490.1"
                     /translation="MEINYKKRNFKSFAKRKNIEISVQRYLIDALSYMALGLFSSLLI
                     GTIFNTLGDNFNISLFTEVISPLAKQVTGPAIAVAIAYGLQAPPLVLFSCALVGACGN
                     ELGGPVGAFVATLFAVEVGKLVSKETKIDILVTPAVTILIGVLVAELIGPAVSAFMTS
                     FGNIIMQATTMQPIIMGALVSALVGIALTLPISSAAICMMLSLGGLAGGAATVGCCCQ
                     MVGFAVMSFRENGVGGLVAQGLGTSMLQVPNIIKNWKIWIPPTVASILLGPLSTTIFK
                     MENIPIGSGMGTCGLVGQFGTVTAMQSAGKGGISMWVGILLLNFILPAIVTLLISEFM
                     RKKGLIKPEDLKLDV"
     gene            8052..9587
                     /locus_tag="PC465_003211"
     CDS             8052..9587
                     /locus_tag="PC465_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650491.1"
                     /translation="MIFVKNKKYRKIAIIISIPILLVAQYYLFKFGILRPMVKGVEIE
                     IVDGEYVKDIDKYVVKLNETVTLSTGEYIKVPSYAKNPNIWFNVLDNSGTLKIDGNKM
                     TALKVGYSSVGIMKNSRVLKKATIKVVDPEVESLDMEINGDLKHVGDSATIESTIEVD
                     YDKFKKSYKPVYKSSNENILKIKGNKVSAVGVGKATIYAKCGNKEIERTFRIQARVAE
                     INMDDIKIEVDQNEKLKPDIITSPPGLEPPKIYYELVDSKLPVERAISLSSNGNVVGL
                     REGKDRVRITCGDKSKVITVTVVKETITNDYIQNLVGSHKIVNNKVIIKLEWDYMKDV
                     FDYDIYLKDKLSGESFKKIKSITINESDLGKSNKVYATIEVDMKGNQNIDFDIYVIGK
                     KDSDTTKPSNVINITNGNGNSNNDNNIKDMRVENISANVDRDNNVIRVNWSSISHKDC
                     TYSIYVKNNTNGDGEFTLYQSDIQGNEHTISIPEGDLNLDIYVVANYNGNSSQNSDVI
                     NVR"
     gene            complement(9772..10458)
                     /locus_tag="PC465_003212"
     CDS             complement(9772..10458)
                     /locus_tag="PC465_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HDF2650492.1"
                     /translation="MKTIGLIGGMSWESTITYYQVINTVIKERLGGLHSSKCILYSVD
                     FQEIEECQSSGNWEKSAKILADAAIKLQEAGADFIVICTNTMHKVSDKIQESIHIPLL
                     HIADVTATVLREKEIKKVALLGTKYTMEQDFYKNVIINNGIEVLIPNEEDRIIVNDTI
                     FNELCLGIISESSKKAFLSIIDKLGKQGAEAVILGCTEIGLLIKQNDTSIPLFDTTVI
                     HAIEAALSSI"
     gene            10583..11965
                     /locus_tag="PC465_003213"
     CDS             10583..11965
                     /locus_tag="PC465_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2650493.1"
                     /translation="MPINSFENYPMTWKPKLDNRKPPIYKTLAMLLEEDIKRGNLNPG
                     DKLPPQRELADFLDLNLSTITRAFKLCEEKGLICAKVGKGTFISSDVNVSNTLLYQTE
                     SKDIIELGTVHPPYEQNTYIIDFIKNVLKQPEMDRFLQYMSPSGTYMQKKSIAKWIER
                     NNVYTSEENILLSTGGQNAICATLLGLFKAGDRIATDSLSFSGIKSIAKMIGIQLVPI
                     PQENNEISIEYLESYCKNENIKGIYLIPDYHNPTTHTMSDLSRKKIAKIAKQYNIIII
                     EDAINSIFRDGIQTPIFSLASDNTIYIFSTSKFLCAGLRVAFVVAPKRYIENLENALY
                     NMNLMVSPFTAEIVHRLLYSPIIDKIIQEKRDAIIERNEVADKVLSDYNLIGDKNCSF
                     RWLLLPDELDGKSFEISAKNLGVQVYCAERFSVGNSTVPKAVRICVTAPKDVEELEKG
                     LNIIKSLLKS"
     gene            12367..13635
                     /gene="eam"
                     /locus_tag="PC465_003214"
     CDS             12367..13635
                     /gene="eam"
                     /locus_tag="PC465_003214"
                     /EC_number="5.4.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 2,3-aminomutase"
                     /protein_id="HDF2650494.1"
                     /translation="MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQ
                     KILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEYIKEVGTQFRWAISPY
                     YLSLIDPEDICDPIKLLSIPTHIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINV
                     TNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDD
                     YLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPIYINTHFNHPMEI
                     TKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHV
                     KGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYV
                     MLRTWEGKVIKMEDEPAVDIKKLIKEQAQD"
     gene            complement(13728..14084)
                     /locus_tag="PC465_003215"
     CDS             complement(13728..14084)
                     /locus_tag="PC465_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650495.1"
                     /translation="MKKALISLLVLSCLLLTAPVNESSYADSQKNVPVSQNTKLTQEQ
                     AKELLVKYNNEVDYIYQGNASDFEALKAKNLNGYVFLPDADGDIGYFVNENTSEIYYF
                     HPSGYLELVNQQQNNK"
     gene            complement(14235..15329)
                     /locus_tag="PC465_003216"
     CDS             complement(14235..15329)
                     /locus_tag="PC465_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF2650496.1"
                     /translation="MQDKKIYLNIVLTVVVSYILIKVIDNYKYFFGVISLLMSLLTPF
                     IIAFVLAYIFNPLVKFLESKLNFKRIYSLLLTYGVLIVILISFILFTVPSIVNSLADL
                     VAQIPTYIDKTEQFLFDLGKSLQSVDPNTLKEYGDKIMSVMPKFSNLLIGSLGGIFST
                     TFSVGKFIVQFLLGFIICFYILLEKEKFLLFTKKVVYISLGKKYGDFIIELCQSLNLN
                     IGKYFTGKILDSFIVGVLSGIGLYFLKSEYALLFGTLMGVMNMVPYFGPVIGMAPVVI
                     INLFSNPTIALTSLIYLIIIQQVEVTFIEPKIVGGQLGLSPFFTILAVTVGGGFFGIP
                     GMILSAPVMGVIKIYFCEFVNRRHDKIQME"
BASE COUNT         6036 a         1924 c         2504 g         5123 t
ORIGIN      
        1 aaaatacagg cgataatcta ttgagtaaac atagaaaaga tgatattata agtatgtgct
       61 aaaatggtta aagcaatatt aatattaaat ttaactataa aacaaaaggg ggcgtttttt
      121 tatgtcaagt acagaaagcg tatctaaaaa aagtggtcat ccgaagagtt tttggcttat
      181 ttgcatgaca attttgtggg aaagatttag ttattatggt ttaacagctt tattggtatt
      241 attttttaca gcaagtgtag ctcaaggtgg tttaggtctt tctactcaag aagcaacatc
      301 catgtttggc ttatttacag gtcttatata tcttacacca ttagtcggtg gctggttagc
      361 agataaagtt ttaggtcaac aaaaatgtat ttctataggt gcacttttaa tagcaatagg
      421 agatttcgta ctatttgctt catctacatc tattgccatg gtttgggtag gtctatcaat
      481 aattatttta ggaaatggtt tttttaaatc aagttgctca aatatagttg gggatatata
      541 tcctaaaact gatgtgtcaa gaaaagatgc agcatacagt ttattctata tggcagtaaa
      601 tgtaggagca tttatagctc caataatatg tggattgctt tctgataatg tatttgcagt
      661 aagaggagca agtggagata tagtatctta tggatataag atggcatttt taatttgtgg
      721 tataggcatg atgttaggta tgattatatt tacacttctt gcaccaaaat tattaaatga
      781 agtcggaaaa tatcctgtga ctaaaggtaa taaaggtgaa aaaattgagt atggaccact
      841 tactaagttg gagaaaaata ggataatagc aatggttatt ttatttttat ttgtggtctt
      901 attctggaca gcatactatc aaacacaaag ttcttttatg atttatgtaa gggataatgt
      961 aaatagaact ctatttggat ttgaaatgcc agtagcatgg cttacatcac taaatgctat
     1021 attatgtgtg gctttatgcc cagtattagc taccctatgg gttaaattat ctcataccaa
     1081 aagaggtgat ttctctattc cagttaaaat gggattagga atgataataa tgggtgttgg
     1141 gtttatagtt atggtatttg ctacattagc taatggtcca gatggaatgg taaaggctag
     1201 tatattgttt atagtattga cttatatatt tacaacagta ggtgaattat tcttatctcc
     1261 tataggactt gcaatgttca ataaattagc tccagctaag tatgctacgt tgtctatggg
     1321 agcctggtat ctaacaagtt tttttgcaag tttattatca ggaaagattg ctggttttac
     1381 agccacactt ggttttttac agatatttgg aggaatagca acagttttaa taatatttgg
     1441 tttaatatta ttgggaataa gaaatgtatt aacaagatta atggctatgg atttactaac
     1501 aaaagaaaaa taattcatga cgaattattg taaataaatg aattacttta aataaaggaa
     1561 gttacattta aatataaaat taaatgtaat ttcctctttg attatgaaaa aaagctttac
     1621 acaaatagat attataatta aaattataat tgtgataatt agagtgtata agatttatat
     1681 aaattataca aaaaatattt atgtaataaa ctttacatac ttatatattt agttattcaa
     1741 actattattt cgaggaggtc ttgttgtgaa tataaaagat agattaagtg gattaagaaa
     1801 atttatggaa gaaaaaaata tagatgccta tatgattcca tcttctgata atcaccaaag
     1861 tgaatatgta ggagattact tcaaatcaag agaatttata tcagggttta atggttcagc
     1921 agggacggtt attgtgacta aagacgaagc tgggttatgg acagatggaa gatattttat
     1981 acaggcagaa tctcaattag aaggaagtac aataaaatta ttcaaaatgg gacaagaagg
     2041 ttgcccaact acagatgaat atttatataa aaatattcct gaaggaggaa ctttaggatt
     2101 tgatggtaga gttatatctg ctagagaagg agctacatta gctgaaaaat tatctaaaaa
     2161 aggtataaag atagaatatc agtatgattt aatagatagt atatggccag atagacctgc
     2221 tttatcagat agtaaagcat ttttattaga tgttaaatat tgtggagaaa gttttagctc
     2281 aaaattagct agattaagag aaaaaatgag tgaaaaaggt acttctactc atgtaataac
     2341 tactcttgat gatatagcat ggttattcaa tataagaggt ggagatgtta aatataatcc
     2401 agttgtactt tcttatgcag taataacttt aaaagaagtt tatctatttg ttgatgaaag
     2461 taagttaaat gaagaaatac taaatgaact agctaaggaa aatgttcaaa taaagccata
     2521 taatgatgtg tatgaatttg taaaaaatat agacaaaact gaaaaagttt tattagatgg
     2581 aactaagctt agttatacaa tttacaataa tataccttgt gaagttgaga aagttgatga
     2641 gttcaatcca gtaatgtttt ttaaagctca aaaaaatgag gtagaattag aaaatataag
     2701 aaattcacat gtaaaagatg gtgtagcttt cactaaattt atgtactggt taaagaaaaa
     2761 tgtaggtaag atggaaatca ctgaaataag tgctactcaa aaattagagg acttaagaag
     2821 agagcaagaa ggtttctttg agccaagttt caatacaatt gctgcatata aagagcatgc
     2881 tgcaatgatg cactatagtg caactccaga gtcaaattat aaattagagg cagaaggatt
     2941 atttttagta gattcaggtg gacaatatta tgatggaact actgatataa ctaggactac
     3001 agttttagga cctataagtg atgaattaaa actacacttt acttctgtag caagaggaat
     3061 gataaatctt tctaaggcta agttcttgca tggttgtaga ggatataact tagacatact
     3121 atctagaagt tgcatgtgga atatgggaat tgattatcaa tgtggaactg gacatggtat
     3181 aggatttgtg ctaaatgttc acgaagctcc aaatggattt agatggagag tagtacctga
     3241 aagatttgat agtgcagttc ttgaagaagg aatggtaact actaatgaac caggtatata
     3301 tatagaaggt tctcatggta taagaacaga gaatgaaatt gtagttagaa aagctgaaaa
     3361 gaatttctat ggtcaattta tggaatttga agttgttacg ttagctccta ttgacttaga
     3421 tggtatagta ccagaattaa tgaataagga tgaaaaagat tatttaaact ggtatcataa
     3481 gttagtttat gataaaatat cacctttctt aactgatgaa gaaagagaat ggttaaaagt
     3541 ttacactaga gctatatagt ttgtactaga tacaataaaa atcgaggtat tataatgcct
     3601 cgatttttta ttgtatattt tattaacttt aaaaaatttt taatttgata attctactaa
     3661 ttttttattc attataagta gtataattcc aaatatcaat aaaaatgatg gtatcactat
     3721 gaagacttgt aacataccaa gttggtctat aatagcttgc gtatagccag ataatttatt
     3781 tgctgcaaat ttgcctaaaa accaaacacc cattagtaat gaaatatact tttcaggcga
     3841 aagtttattt accataccat acccgactgg agaaaagcaa atttctccta tactttggaa
     3901 tgttaaaaat ccaactaccc aaaatacact tgctttgtga attgaattag ggtctgttcc
     3961 tgtttgtata actgctacta tcataaacaa aaatgctatg gctaatagta taaaacctaa
     4021 gctcattttt tttggcacac ttaaatcgcc ttttttagtt tgagataatt ttacccatac
     4081 taaagcagag ataggtccaa gaataacaca aaggagacca ttgtatgaat ctatccatga
     4141 agtaggaatt tgaaaattgc caacagtaag atttatgtgt tcctttgtat agagtgcaat
     4201 agacatagag gcttggttat atgctatcca aaaaaatact gtgaaaaaag ctaacaccaa
     4261 tattactatt attctttttt tctcaatcaa agttaaaggt cttgaagcga gcattttctt
     4321 atattctagt gattttctta tagactctct cccgttaata gggtcattat tcaaaggttt
     4381 ataaaacttt ctgtttccaa atataaagaa gaataaacct attagaaccg taattgatga
     4441 aaataaaaat acatatctat atccatacat acttatagat aatccgcttt tcatagcaaa
     4501 ccattcatta gcaactaaac cgcatattaa agggccaaat aaagtaccta gattagtagc
     4561 catatacgta atagagaaag ctccatcttt tcttgggtca tcattggtat ataagtttcc
     4621 aaccatagta tgtaagtttc ctttataaaa acctattcct aatccagata aaaatatcat
     4681 gatgtttata tccatcttac tatttgctat gtatcctaga aaataaccaa ttgaaaccat
     4741 tagcattcca agtataatac agtttttggg acctaaaaat ctatcactga cccatccacc
     4801 aataactgga gagaaataag tccatgctaa aaaagatgca agcattgatg cggattctgc
     4861 tggtgttaac cctaaaccac ctttggagac ttgttcagct aaaaacaata ataataccaa
     4921 tttcatacca tagtatgcaa gtcctacaaa ggtaaatatt gaacagcaga aatataaatc
     4981 tctaggttgt ttaagttttt cttgcgtttt taaaactgac atatgtcgag aacctccaga
     5041 taaatagttt aacaaaattt taccatacta tatgagtata tgtttttttc atatagacgt
     5101 caacttgtaa gataatttaa ttaagtcgaa atatatgtaa aaatagtatc atttttgtgt
     5161 attcagtaat atttttttat gataatatat gttattatta tattaaaata caaacatatt
     5221 tatggaaagg atatgccaat ttagtagtta gattgattgt ttggcaggtg ggatgagcta
     5281 tgataagaaa gaaatctgaa ttacaagtag aagtaaaaga aaatttaaat ggtggtatag
     5341 gaaaggttaa gcttgaaaac ataatacaaa atgaagagct taaaggaaaa ggaagactat
     5401 ttaaaagagt agctttacca gtaggaagtt caattggtgt gcatgaccat acaacagatt
     5461 ttgaagtata ttatatacta aagggaaaag gtaaagtatt tgataatggg gaatttgtag
     5521 aagtaaatga gggtgatgta gtgtatacag ctgatggcga aaaacattct atagaaaata
     5581 taggagaaga agatcttgag tttgtagcac tagttttata tatgtaaaat atggaggagg
     5641 agtcatgaca ggcaagatag aagaaattaa ggacaagata aatagatttt gcaactccaa
     5701 tttaaatcaa gaatacaaag atataagctt taaaattttg caaaaccttt tagataataa
     5761 taaagagata attcattctt ctagagctga tatatggtct tcagctatac taaatatagt
     5821 tttagaacaa aatcttttat acaataagaa gcatccacta catataacaa aaaaagagtt
     5881 ttcaaaacaa ataggtgttt ctttaaatac tataaataat aaatcgtctt taataaaaga
     5941 tgtttgtagt attgactttt taaatcaaga tactatagct atttctaatg tagaattttg
     6001 ggtaaaagag actaattcca aatcaaagtc tgtagattta gatttagaaa agaaaaaaat
     6061 actatataaa agatatatta agctatcaca agatgcgaat agtgatattg aatcaattag
     6121 atatatggag gaagctgtaa atataggtaa aagtatgatt actaaagaag ataaagaact
     6181 tggattttgg aaaggtttat ctaccagagc ctatatgata gcacttgaat cccttgctag
     6241 aaagttagaa agtattaata atctaaagga gtccaaaaaa gtattagaat atttaataga
     6301 aattaatcct agtgatgagc agggaataag atacaaatta ttaaatgtat taattagatt
     6361 aaatgataga acttcaataa ataaattatt tgaactttat aaagaagaaa aatctgctac
     6421 atggatgtac agtaaagctc tttattactt taaaaataaa agtatgtttt tggcaaatga
     6481 ttctattaag gttgctagaa gtaaaaataa gtacgttgga ttatatttgt tagattggcg
     6541 aaatgctttt ggtagagaat ttgttacaga ggaagaaaag gcagaagctg tctattacta
     6601 tgatgaaaac atagtgattt ggaatgaagt taaaggttct atggattggc tattaaaaaa
     6661 aatgttggaa ttttcataaa aaaaactact ccttactttt atataagtaa aaggagtagt
     6721 ttttaattta tacatctagt tttaaatctt caggttttat tagacctttt tttctcataa
     6781 attctgaaat caacaaagtt acaatagcag gaagtataaa attaagtaaa agtataccaa
     6841 cccacataga tatacctcct tttccagcac tttgcatagc agttactgtt ccaaattgtc
     6901 caaccaatcc acaagtgccc ataccagaac caataggaat attctccatt ttgaatattg
     6961 ttgtagataa tggtccaagt aatattgaag ctacagtagg tggtatccaa attttccaat
     7021 tttttattat attaggtact tgcaacatag atgtcccaag accttgtgcc acaaggccac
     7081 caactccatt ttccctaaag ctcataacag caaagcctac catttggcaa caacaaccta
     7141 cagttgctgc cccaccagca agaccaccta aacttaacat catacaaata gctgcactac
     7201 ttataggtaa tgtaagagct attccaacaa gtgcagagac taaagctccc attattatag
     7261 gttgcatagt tgtagcttgc attattatat ttccaaatga agtcataaaa gcagaaacag
     7321 ctggaccaat aagttcagct acaagtactc caattagtat tgttacagca ggtgtaacca
     7381 atatatctat ttttgtttct tttgaaacta attttccaac ctctacagca aaaagtgtag
     7441 cgacaaatgc tccaacaggt cctcctaatt cattaccaca agctccaaca agtgcacaag
     7501 aaaatagtac aagtggaggt gcttgaagtc catacgcaat agccactgct atagctggac
     7561 cagtaacctg tttagcaaga gggcttataa cttcagtaaa aagagaaata ttgaaattat
     7621 ctcctaatgt attgaaaatt gttccaatta aaagggacga aaaaagaccg agtgccatat
     7681 aacttagtgc gtcaataaga tacctttgaa cagaaatttc aatatttttt cttttagcaa
     7741 atgatttgaa atttcttttt ttataattga tttccaattt aaaatcctcc tcatataata
     7801 taagtataat ttctttttaa ttaattatat aacttttcag ctgacaagac aaatgttatt
     7861 tcactaaaat tagactattg taatagtaag aaattaacat taattttagt tttaaatttt
     7921 aaatttatgg tttataatta gtatagggat attctgaaat ataataattt tccagtttat
     7981 cccaatattt aacttaggta gattgcttac aaaacaaatg attatatatt aggctaaaag
     8041 gaagtggata gatgatattt gtaaaaaata agaaatacag aaaaattgcc ataattatat
     8101 ctattcctat attgcttgtt gcgcagtact acctttttaa atttggaata cttagaccaa
     8161 tggtaaaggg agtagaaatt gaaattgtag atggggaata tgttaaagat atagataaat
     8221 atgtagtaaa attaaatgaa acagttactt tgtctacagg tgaatatatt aaggttcctt
     8281 cgtatgctaa aaatccaaat atttggttta atgtattgga taactcaggg actttaaaaa
     8341 tagatggaaa taaaatgaca gcattaaagg ttgggtattc ttctgtgggt atcatgaaaa
     8401 attcaagagt attaaaaaag gctactataa aagtagtaga cccagaggta gaatcactag
     8461 atatggagat taatggggat ttaaaacatg ttggtgatag tgctactata gaaagtacaa
     8521 tagaagttga ttatgataag tttaaaaaat catataagcc agtttataag agtagcaatg
     8581 aaaatatttt aaaaatcaaa ggaaataaag taagtgcagt tggagttggt aaagctacaa
     8641 tatatgctaa gtgtggaaat aaagaaattg agagaacatt taggattcaa gctagagttg
     8701 ctgaaataaa tatggatgat ataaaaatag aagttgacca gaatgaaaaa ttgaaaccag
     8761 atataataac ttctccacct ggtttagaac caccaaaaat atattatgag ttagtagatt
     8821 caaaattacc tgtagaaaga gcaataagtt taagtagtaa tggaaatgtt gtagggctta
     8881 gagaaggtaa agatagggtg agaataactt gtggagataa atctaaagta ataacagtaa
     8941 cagtagtcaa agaaactata acgaatgact atatacaaaa cttggttggt tcacataaaa
     9001 tagtaaacaa taaagttatt attaaacttg aatgggatta tatgaaagat gtctttgatt
     9061 atgatatata tcttaaagat aagttgtcag gagaatcatt taagaaaatt aaatctataa
     9121 ctataaatga aagtgattta ggtaagtcta acaaggtata tgcgactata gaagtagata
     9181 tgaagggtaa tcaaaatata gattttgata tttatgtcat agggaaaaag gattcagata
     9241 caactaagcc aagtaatgta ataaatatta ccaatggaaa tggaaattca aataatgata
     9301 ataatattaa agatatgagg gtagaaaata tatcagctaa tgttgataga gataataatg
     9361 tcattagagt taactggagt agtatatctc ataaggactg tacttacagt atatatgtaa
     9421 aaaataatac taatggagat ggagaattta ctctatatca aagtgatata cagggaaatg
     9481 agcatactat aagtattcct gaaggagatt taaatctaga tatttatgtt gttgcaaatt
     9541 ataatggaaa tagctctcaa aatagtgatg ttataaatgt aagatagatt tgtatacaaa
     9601 ttgaaagtgt tgagtttatt taaatattaa attaagaaaa aggatagtat agggtaatta
     9661 tactatcctt ttttgttaca atatataggt ttaaaatctc tagtaatata aattataaaa
     9721 agtcttattt acacaaatct atagatattt tttttattaa tcaatattgt cttaaattga
     9781 acttagtgca gcttctattg catgtattac tgtcgtatca aatagtggaa tagaagtgtc
     9841 attttgttta attaaaagac ctatttctgt acatcctaat ataacagcct ctgcaccttg
     9901 tttgccaagc ttatctataa tagataagaa agcttttttt gaagattcag atataattcc
     9961 taagcaaagt tcattaaata ttgtgtcatt tactattata cggtcttctt catttggaat
    10021 taagacttca attccattat taataattac atttttataa aaatcttgtt ccattgtata
    10081 tttagtacct aataaggcca ctttttttat ttctttttcc cttaataccg tagcagttac
    10141 atctgctatg tgaagtaatg gaatatgtat actttcttgt attttatctg ataccttatg
    10201 catagtatta gtacagataa caataaaatc tgcccctgcc tcttgtaatt taattgcagc
    10261 atcagctaaa attttggcgc ttttttccca atttccacta gattggcatt cttcaatttc
    10321 ttgaaaatct acactgtaaa gtatacattt agaagagtgt agtccaccta atctttcttt
    10381 tattactgta ttaataactt gataatatgt aatggtactt tcccaactca taccaccaat
    10441 taagcctata gtcttcatat tatacctctc ttatttattt attttgaaat agctatttac
    10501 aaatacaagt atagcatcta aaatagaagc atacaataat aaaattgtat ggagtacaat
    10561 tataattaag aggagtaatt atatgccaat aaattctttt gaaaactatc ctatgacatg
    10621 gaaaccaaaa ttagataacc gaaaaccacc aatatataaa actttagcaa tgttattaga
    10681 agaagatatt aaaagaggaa atttaaatcc tggagataaa ctgcctccac aacgggaatt
    10741 agcagatttt ctagatttaa acttaagtac aataacacga gcatttaaac tttgcgaaga
    10801 aaagggacta atatgtgcaa aagtgggaaa gggaacattc atttcttctg atgtaaatgt
    10861 aagtaataca ttattatatc aaacggaatc aaaagacata attgagttgg ggacagttca
    10921 tcctccgtat gagcaaaata catatattat tgactttatt aaaaatgtac taaaacaacc
    10981 agaaatggat aggtttttac aatacatgtc tccatctggc acatatatgc aaaaaaagtc
    11041 aattgcaaaa tggatagaaa gaaataatgt atacaccagt gaagaaaata tattattatc
    11101 tacaggaggg caaaatgcta tatgtgcaac tttactagga ttatttaaag ctggtgatag
    11161 aattgctaca gattctttaa gtttttctgg aattaagtca atagctaaaa tgataggtat
    11221 tcaattagtc ccaattcctc aagaaaataa tgaaatatcg attgaatatc ttgaaagtta
    11281 ttgtaaaaat gaaaatataa aaggcatata tcttatacca gattatcata atccaacgac
    11341 acatactatg tctgatttat ctcgtaaaaa gatagccaag atagcaaagc aatataatat
    11401 aataattatt gaagatgcta taaatagcat ttttagagac ggtatacaaa ctcccatatt
    11461 ttctttagct agtgataata ctatatatat ttttagtaca tctaaatttt tatgtgctgg
    11521 tcttagagta gcatttgtag ttgctccaaa acgatatata gaaaatttag aaaatgcact
    11581 atataatatg aatctaatgg tttctccatt tacagcagaa atagtacacc gtttattata
    11641 ttctcctatt atagataaaa ttatacaaga gaaaagagat gcaattatag aaagaaatga
    11701 agttgctgat aaagttttgt cagattataa tttgattggt gataagaatt gcagttttcg
    11761 ttggttactt cttcctgatg aattggatgg aaaatcattt gaaatttctg caaaaaatct
    11821 aggagttcaa gtatattgtg ctgaacgatt ttcagtagga aactctacag ttccaaaagc
    11881 agttcgtatt tgtgtaacag ctccaaaaga tgtagaagaa ttagaaaaag ggcttaatat
    11941 aataaagtca cttcttaaga gttaaattta ttttactatt atttaattaa ataaataaaa
    12001 aggcggagaa atttattata ataaacctcc gcttttatta tttaatgaaa tactttactt
    12061 tttattaaaa aatttaattt taataatctt gaaaatataa tcgttttatg gtaaaataat
    12121 tcttaaaaat agaaaaaatt aatcatttgt taaaaaaaat gcataattta ttgtaattta
    12181 ttgacgaagg ttgaaaaata ttcataaatg tgcgaaataa cagaaaaaat gcaaaaatta
    12241 attcaatttc atttgttata aaatctatat ggcaaaatta aatctgccta tcagaatgat
    12301 ataaacacat cagaaaggag gacgctatca aataatacaa gtagttaact ttgatagcaa
    12361 aaaattatga atgaacaaac tagaatatcc ttagagagag ctgctgaatt aaaatcaaaa
    12421 attgatgatt atattcaggc tagaaaaacg attaacagag gtcttgaaaa agaagaagag
    12481 ataaataaac gaaaacagaa aatattaagt atcttaaatg gaactgaaga ggattggaat
    12541 aactacaaat ggcaattatc aaatagaata acagatgtag atactttatc aaaaattata
    12601 actctaacta aaaaagaaaa agaatatata aaagaggttg gtactcaatt tagatgggca
    12661 atatctccat attatttgag tcttatagac ccagaagata tatgtgaccc aataaaatta
    12721 ctgtctatac caacacatat agagttggaa gatgaacaag aagatttgga cccaatggga
    12781 gaagagtata caaacccagc aggatgtata actagaagat acccggatag attaataata
    12841 aatgtaacaa atgagtgtgc tatgtattgt agacactgtc agagaagaag aaatattgga
    12901 caacaagatt ctcataagtc aaaagctatt atccaagaat ctatagacta tatcagagaa
    12961 aatgaagaaa taagagatgt actagtaact ggtggagatg ctcttacatt aaaagatgat
    13021 tatttagagt ggattcttag ccaacttaaa gagataccac atgttgatta tgttagatta
    13081 ggtactagga ctcttgttac aatgccacaa agaattacag atgaattttg caatatgcta
    13141 aaaaaatatc accctatata tataaatact cattttaatc atccaatgga aataactaag
    13201 gaatctaaag aagcttgtga aaagttagca aatgcaggag ttccattagg aaatcaggca
    13261 gtattattaa atggaataaa taatgataaa tttgtaatga gatgtttaaa tcaagaatta
    13321 ctgaaaataa gagtaaaacc ttattatata ttccaaagta aacatgtaaa gggaacaaaa
    13381 catttcaata catcagtaga tgatggtctt gaaatcatgg agtatttaag aggatataca
    13441 tcaggaatgg ctataccaac atatatagta aatgctccaa aaggaggagg aaagactcct
    13501 ttgcttcctc aataccttgt atcaaaagga acagattacg ttatgcttag aacatgggaa
    13561 ggaaaagtta taaaaatgga agatgaacct gctgtagata taaagaaact tataaaagaa
    13621 caagcacagg attaaaaaaa tatttaaagt ttataaaaag aaacaacttt aaaataaaaa
    13681 gaaaatggat gtcaaattta tatcaatttg catccatttt ttattagtta tttattattt
    13741 tgttgttgat taactaattc aagatatcca cttgggtgga agtaatatat ctcagaagta
    13801 ttttcattta caaagtaacc aatatcacca tctgcatctg gtaaaaatac ataaccatta
    13861 agatttttag cttttaatgc ttcaaaatca ctagcatttc cttgatatat gtaatcaact
    13921 tcattgttgt attttactaa aagttcttta gcttgttctt gagtcaattt agtattttgg
    13981 cttacaggaa cattcttttg agaatctgca taagaagatt catttactgg tgcagttaat
    14041 aacaaacaag ataaaactaa taaagatata agtgcttttt tcatactaaa accctctttc
    14101 atgtttaatt atataagatt cattacttaa taatattgta tgtttcctat aattaaatat
    14161 taccattaaa gagaataata ttacagttac acagctgtaa cttttgatta caaaatcgta
    14221 attaaattgt atttttattc catttgtatt ttatcatgtc tacgatttac aaactcacag
    14281 aagtatatct ttataacgcc catcacagga gcagatagaa tcataccagg tataccaaag
    14341 aatcctccac caacagtaac tgctaggatt gtaaagaatg ggctaagacc tagttgtcca
    14401 cctacgattt ttggctctat aaatgtaact tcaacttgtt gaattattat taagtaaatt
    14461 aaagaagtta aagcaattgt tggattggag aataaattaa ttattacaac tggtgccata
    14521 cctattactg gaccaaaata tggaaccata ttcatgacac ccataagtgt accaaataat
    14581 agtgcatatt cagattttaa aaagtaaaga ccaattccag aaagtactcc aactataaaa
    14641 gaatctaaaa tcttacctgt aaagtattta ccaatattta aatttaagct ttgacatagt
    14701 tctattataa agtctccata ttttttacct aaggaaatat aaactacttt ttttgtaaac
    14761 agtaagaatt tttctttttc taataatata tagaaacaaa ttataaaacc taaaagaaat
    14821 tgtactataa attttccaac tgaaaatgta gtgctaaata tcccaccaag tgaaccaata
    14881 agcaagttac taaatttagg cattacactc ataattttgt caccatactc ttttaatgta
    14941 ttagggtcaa ctgattgtaa actcttacct aagtcgaata agaattgctc tgttttatct
    15001 atgtatgtag gaatttgagc aactaaatca gctaaactat ttactatgga tggaactgta
    15061 aataatataa aggaaattag tataactatg agtacaccat aagtaagaag taacgaatat
    15121 attctcttaa aatttaattt gctttctaag aactttacta gtgggttgaa tatatatgct
    15181 aatacaaatg ctattataaa tggtgttagt agtgacatta ataaacttat cactccaaaa
    15241 aaatatttgt aattatcaat aactttaatc aagatatatg aaacaactac agtgagtaca
    15301 atatttagat aaattttttt atcttgcaaa ataacacaac ctttcttata tttattaaat
    15361 ttagatatac ttaaatctaa gttaaagtta atatttatag cttattatac aataaaaagc
    15421 agtattaata tagtatgatt aatatgaaat tataaatacg ttaaaacttt atgtttatag
    15481 ctaaaataat aaaaattatt tatattgtgt ttatatataa tctaaaatga aaaaaagtgg
    15541 tgcctttgat taaactaagt ttttataatt taaattttgt acaataa
//
LOCUS       DAMJXI010000082        15493 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.087, whole genome shotgun sequence.
ACCESSION   DAMJXI010000082 DAMJXI010000000
VERSION     DAMJXI010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15493
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.087"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            47..898
                     /locus_tag="PC465_003217"
     CDS             47..898
                     /locus_tag="PC465_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HDF2650497.1"
                     /translation="MKNIISAKELISKLEKNDNLVVIDCRFDLINRTYGIDSYKKGHI
                     KGSFILDIDKDLSSPTKEHGGKNPLQDPLILKEKLEKMGVDNDTTIVTYDDGDLNGAC
                     RLFFQLKHLGLKNVYVLDGGITSFVKEGGELEEKVNIPSCTGKEIRPNINNGLVVPME
                     YVKSKLYKKDTVIIDCRANERYQGLVEPAYSKAGHIPSAKNYFCKDLIKSDFENGSLK
                     DIEFLKKFFKDLNNYDEVILSCGSGISACVNSLALRELDIPHKIYIGSFSDWISYDDN
                     EIKTGQE"
     gene            complement(1031..2644)
                     /gene="ggt"
                     /locus_tag="PC465_003218"
     CDS             complement(1031..2644)
                     /gene="ggt"
                     /locus_tag="PC465_003218"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HDF2650498.1"
                     /translation="MKFNAYQHKYSSIRNVVYAKNGAVATSTPLASQAGLEILKKGGN
                     AVDAAVATAATLAVVEPTSNGIGGDAYALVWIEEEKRLYGLNSSGFAPENMELKNYNN
                     MKEMPKYGFGSVTVPGIPAAWSELNKKYGKLSLMECLSPAINYAREGYVVSPNVAKVW
                     KKSYELYEKELIGEEFKPWFDTFSKDGKAPEAGDIFICEEQASTLEEIANTQAESFYR
                     GRLADKIDEYSKKFNGAIRKSDLECFYPTWVEPISTEYKGYKIFEIPPNGHGITVLMA
                     LNILKELELEGNIENVEDIHKIIESLKLAFADSKTYVTDIEHMKVKIQELLSQEYAKK
                     RSLLIDNKEALYPTAGEPYCGGTVYLCTADKDGNMVSYIQSNYINFGSGIVIPRTGIA
                     LHSRGNNFNLDPKHHNVVKPFKKPYHTIIPGFLGKEDKAIGPFGVMGAFMQPQGHIQV
                     LTNMIDFGLNPQEALDAPRWQWIKGKEIEVEPEMPKHIIDSLIEKGHEIKVIHDTVDM
                     GRGQIIFKTEQESYICGTESRCDGHIAVY"
     gene            complement(2869..4806)
                     /locus_tag="PC465_003219"
     CDS             complement(2869..4806)
                     /locus_tag="PC465_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2650499.1"
                     /translation="MTLFRIAMQNVKNSFFNYLMYFISIVFSVFVFFSFKSIEYNEAL
                     SSLGEKTRMSINTSSIVIVVFVFLFIYYSNSFFFNRRRREVGTYSLLGMRKNQIGKIF
                     LYETFLMGIVAILIGIFLGLLFSKLMTMMLVKLMNEMIVVNMNLSIKALVQTLAVFLI
                     IFIVIGIRNTIVIRNKRIIELFNKYPEKYKFKKFIKLKCVLGVLLITISYLMSISYFI
                     AENIMLSVFILVTIIPGTFLFFSSTMYMIIDAVKKRKSFYYKGQNLIAFSELGFKLKS
                     NSSVLAVIAILIATSVTMLGFTISLYYDIDRNISENYKYSYTINLGNSYVNNEIDKLL
                     YKYKKDNKIIFDKTIELIDKDINIEMYYKNGNSYIEDRTSVDIIRESDFKKLRQYQNN
                     NYEELTSKESVYYVSDSYKKIFFKDFEIEKINLHIKDTNEYDINLFKVQKSILEPEIN
                     SQATFDLIVVKDDVFNQLKLHGNSRLIRLIDIKNEKKELDLTLKLKNIVSENMKFTYP
                     FNFTSSIESYNNLIKLSGLMLFIGIFLSVVFLLCTGSIILFKQLSNIYDDKERYIMLI
                     KLGANNKDIEKIISKQLKVIFLMPLVVGTVHNLFAMSIAQKFIPRSLLVPIIITLVIY
                     FIGYFIYYFLTLKYALNMIKE"
     gene            complement(4793..5560)
                     /locus_tag="PC465_003220"
     CDS             complement(4793..5560)
                     /locus_tag="PC465_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003722224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2650500.1"
                     /translation="MEEILYVENIKKEYGRKGSKHEALRGITFKVYKGEFVGIMGSSG
                     AGKSTLLNIISTIDLPSSGDIYINGKNTIKMKQNELADFRRDNLGFVFQDSNLLDTLT
                     IKENIMLPLSLKNERVSVIENRIKEISKELNIESILDKYPGEVSGGQKQRGAVCRAIA
                     TKPSLVLADEPTGALDSKSARDLLNCLLKLNKDSNKTILMVTHDAISASFCNRILFIK
                     DGIIFTEIVKGESNREFYNKIVNTVSLIGGVNKNDFI"
     gene            5848..6522
                     /locus_tag="PC465_003221"
     CDS             5848..6522
                     /locus_tag="PC465_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2650501.1"
                     /translation="MFKIMVVEDDVSLKNIIAKCLTKWGHDVHQIENLENIIEEFKNY
                     NPELVLLDINLPFYDGFHWCNEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKP
                     FSVDVLVAKVNALLRRTYNFVDNNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKI
                     LHELMKYKGQIVSRNKLMKKLWDNDWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRG
                     LGYIIS"
     gene            6546..7550
                     /locus_tag="PC465_003222"
     CDS             6546..7550
                     /locus_tag="PC465_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2650502.1"
                     /translation="MSFKDFLKDKLGFLVYNFTFLIFTVSVIIFSPVDVFLTDTILYI
                     LVVNVVFLFLYLFISYIKKNKFLDKIKNDTFKINMNDIELARCKNEEKIYLNIIKNHQ
                     YQCNNIINNNIEKFEENKEILNMWVHDVKIPIAIIKLILEQNENLIDEKISDDIDSEI
                     FRIENSVEKILYLSRLEDFHKDFLIQEVNIEKIIRNIIKKYSKYFISKKIILDLNNLN
                     FKVLSDEKWLYFIFEQLLSNSLKYSSLGDNISIYCKRTKNYLQLRVEDTGCGIKKEDL
                     NRIFNKGFTGNNGRNNSKSTGLGLYLVKELCDKLGHKIDVDSEYNQYTKFTITFKCDL
                     "
     gene            7662..8891
                     /locus_tag="PC465_003223"
     CDS             7662..8891
                     /locus_tag="PC465_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HDF2650503.1"
                     /translation="MSFLKKFKNKRFRNNSFKSNNFRNSSFGSSGFKSKNKGFKNNPF
                     KNKRFKIYAGIAVIILLILGVLAYVDSKNTELQANENFIETYTIPENEKIFINGMVVP
                     KQTKDFNISGDYELSDVNVTNGQKVNQGDLLFTAKNPTIIAEIDSLKSQLSQYKKQKI
                     SLSDIAENKDAIASINAQITALNSQIASLDKKAYDRVTAPFDGTVYLNDQTGNPDQPV
                     SFMTIQGLEFYMKGQASEQDLPKMKIDQMVNILVFSTDQKLTGRISFISDKPSTPNTE
                     MGAQQNTLSYYDINIAFDNQEGLVNGFHLQASLEVANSSFKIPASCVLKDNKHSYVFK
                     DLDGILKKQIVDVASQNDDFAVVRGGLEQGDIIIKHPTKEMKEGDPVQGDGVTAGSNN
                     GDTTPNKKVEEVTMDVN"
     gene            8899..9573
                     /locus_tag="PC465_003224"
     CDS             8899..9573
                     /locus_tag="PC465_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2650504.1"
                     /translation="MLIKLENIQKYYKVGKDELHVLKSLNLEIESGEFVMIMGKSGSG
                     KTTLLNILGFLDVFDEGRYIFDGTDVTNLSENERSVFRNINIGFVFQQFNLIETLNVY
                     QNVELPLIYNKALKKSNREEIVKDKLSSVGLLDKLKQKPLQLSGGQQQRVAIARCLAN
                     DPQIIFADEPTGALDSETSREIMELLTRLNKQGKTIIMVTHDQDLTKYATKVIRLKDG
                     VFTSEV"
     gene            9576..10808
                     /locus_tag="PC465_003225"
     CDS             9576..10808
                     /locus_tag="PC465_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2650505.1"
                     /translation="MSLLKNSLANLKGHKLRVFVALLWIIIGITSVILVSSIGNGFQK
                     EIKKSVNNVNPNKTTISFESADNTGLTDDMSIFLKPFNAKDLEELSFVEGVERIAPSR
                     DGFNLDSVYSSQASFDKKTTYVDVGPVKKDSKINLICGRDFSLDDEKRKVILLTLQST
                     SEIFENPEDALGHGININGTIFEIIGVLDDSQQNQAGGFFGGYQDMQFTTSLVPKKAF
                     DTLMSQNSYSNEIYQLDLVSSKGYNVNEVANNVIAKLYEMHPGINGSYTTPDPTEQTA
                     YLESINSNVNKYVSIITVVAMFVGGIGVMNIMYVSVMERQREIGIRRAIGAKPRSILF
                     QFLVEAVFITVCGGILGTIVGFTATNYVSKYIGFEAIPSLNSLFYAIVATILTGVVFG
                     LIPAFKASKLDPIKAIYK"
     gene            complement(11094..12359)
                     /locus_tag="PC465_003226"
     CDS             complement(11094..12359)
                     /locus_tag="PC465_003226"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HDF2650506.1"
                     /translation="MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKI
                     IDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNE
                     DTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNL
                     IMEAMIKAKELDVPLSFHEEDPSLVGNPGVNAGKVASKLGLKGASSVAEDVMVARDCM
                     LALKTGAKVDIQHISSGVSVDMVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKM
                     NPPLRSKWDRDKIIEGLNDGTIEIIATDHAPHSKEEKDREFIKAPSGIIGLETSLALG
                     ITNLVHKNHLSMMQLIEKMSINPAKLYNLNIGFIEEGAVADIVIFNPEEEWTVESFVS
                     KADNSPFKGKSLYGKVNYTICNGEIVYNA"
     gene            complement(12412..13560)
                     /locus_tag="PC465_003227"
     CDS             complement(12412..13560)
                     /locus_tag="PC465_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HDF2650507.1"
                     /translation="MKSVSVRSCKTYNYEEVKLSIEKNLEDIGGIDKFVKKGSKVLIK
                     PNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQSSLKSIYKASGI
                     EEVANELGIKLNYDVSDVKIHSEKAHVLKYMDIIKPIVDSDYIINLCKLKTHIMATFT
                     GGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGP
                     SAGTTREIGVSLASQNPYAIDVVACKIISLLPNRVATIRGAIKRGYIQEDFSDIEILG
                     EDIKDLIIKNYKIPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKE
                     ACPASTIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK"
     gene            complement(13660..14205)
                     /locus_tag="PC465_003228"
     CDS             complement(13660..14205)
                     /locus_tag="PC465_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HDF2650508.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADE
                     HRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREGYPEVAEAYKRIAFEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKRAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRHFGK"
     gene            complement(14428..15372)
                     /locus_tag="PC465_003229"
     CDS             complement(14428..15372)
                     /locus_tag="PC465_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDF2650509.1"
                     /translation="MQKNKKEGALLKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTP
                     LQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTP
                     SKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFL
                     TLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVVVQTFAGQLKMEAELSGY
                     MGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLV
                     IGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI"
BASE COUNT         5421 a         2419 c         1945 g         5708 t
ORIGIN      
        1 aatataaatt aaaataaaga taatataaac acaggaggta cattctttga aaaacattat
       61 ttcagcaaaa gaacttatat caaaactaga aaaaaatgat aatctagttg taatagattg
      121 cagatttgat cttatcaata gaacttatgg tattgattct tataaaaaag gacacatcaa
      181 aggcagtttt atcttagata tagacaagga tttatcatct cctacaaaag aacatggtgg
      241 taaaaatcct ttacaagacc ctttaatact aaaagaaaaa ttagaaaaaa tgggtgttga
      301 taatgacact acgattgtaa cttatgatga tggagattta aatggagctt gcagattatt
      361 tttccaatta aaacatttgg ggcttaaaaa tgtctatgta ctagatgggg gaataacatc
      421 tttcgtaaag gaaggtggag aattggaaga gaaagtgaat ataccaagtt gtacaggtaa
      481 ggaaattaga ccaaatataa acaatggttt agttgttcca atggaatatg ttaagtctaa
      541 attatacaaa aaagatactg taataataga ttgccgtgct aatgagagat accaaggttt
      601 agttgaacct gcttactcaa aagctggtca tataccaagt gcaaaaaatt atttttgtaa
      661 ggatttaata aaaagtgact ttgaaaatgg ctcacttaaa gatatagaat ttttaaaaaa
      721 attctttaaa gatttaaata attatgatga agtaatttta tcttgtggtt cagggatatc
      781 tgcttgtgtt aacagtcttg ctcttagaga actggatata cctcacaaga tttatattgg
      841 tagctttagc gactggatta gttatgatga caatgaaatc aaaactggtc aagaataagg
      901 ctcataatct atataaaatc agcatatgat agcttaaatt ttgtaaaggc gtcagtcatt
      961 gtagactttc gcctttactt attatttcat atactcttta aatttattat atatatttta
     1021 gttgataata ttaataaact gcaatatgac catcacatct tgattccgtc ccacaaatat
     1081 aactttcctg ttctgtttta aatattattt gacctcgtcc catgtcaaca gtatcatgaa
     1141 ttacttttat ttcatgaccc ttttcaatta atgaatctat tatatgcttt ggcatctctg
     1201 gttcaacttc tatttctttt ccttttatcc actgccatct tggagcatct agcgcctctt
     1261 gtggatttaa tccaaaatca atcatatttg ttaacacctg aatatgtcct tgtggttgca
     1321 taaaagctcc cattacacca aatggaccta ttgctttatc ttctttacct aaaaatccag
     1381 gtattatagt atgataaggt tttttaaatg gttttactac attgtggtgt ttagggtcta
     1441 aattaaaatt atttcctcta ctatgtaaag caatcccagt tcttggtatc acaattcctg
     1501 aaccaaaatt tatgtaattg ctctgtatat atgaaaccat atttccatcc ttatctgcag
     1561 tacaaaggta tactgtacca ccacaatatg gctctcctgc agttggatac aaagcctctt
     1621 tattgtcaat taataaactt ctttttttgg catactcttg gcttagtaat tcctgaatct
     1681 ttaccttcat atgctctata tcagttacat atgttttaga atctgcaaaa gctaatttta
     1741 aactctctat aattttatgt atgtcttcta cattttctat atttccttct aattccaatt
     1801 cttttaatat gttaagtgcc attaaaactg ttattccatg accatttggt gggatttcaa
     1861 atattttata tcccttatat tctgtactta taggttctac ccatgttgga taaaaacact
     1921 ctaagtcact ctttcttata gccccattaa attttttaga atattcatct attttatcag
     1981 caagtcttcc tctataaaag ctttcagcct gagtatttgc tatctcttct aatgtacttg
     2041 cctgttcttc acatataaat atatctccag cctctggagc tttaccatct ttagaaaatg
     2101 tatcaaacca tggtttgaac tcttctccaa taagttcttt ttcatagagt tcatatgatt
     2161 ttttccatac cttagctaca ttaggagata ctacgtatcc ctctcttgca tagtttatcg
     2221 ctggagataa gcattccatt aagctaagtt taccatattt tttatttaat tctgaccaag
     2281 ctgcgggtat tccaggtaca gttactgatc caaacccata ttttggcatt tctttcatat
     2341 tattataatt ttttaattcc atattttctg gagcaaagcc actagaattt aaaccataca
     2401 atcgtttttc ttcctctatc caaacaaggg catatgcatc tcctccaatc ccattgcttg
     2461 taggttctac tactgctaat gtggcggctg ttgcaactgc tgcatcaaca gcatttccac
     2521 ccttttttag tatttcaagt ccagcttgag atgctaatgg tgttgatgtt gcaactgctc
     2581 catttttagc atacacgaca tttcttattg atgagtattt atgttggtag gcattaaact
     2641 tcataaattt cagctcctcg tcatttttta tttgatattc tgcttagatt tattatataa
     2701 catcaagtaa tgtaactgat acaaaatgat ataaaatata gactttttcc taactttaat
     2761 tttatcttta aataaatatc ttaaactcaa ttctagtatt ttctatctgc acttaaataa
     2821 gttattttat tcaaaacata tatctaattc ttttgactta aaaataattt attcttttat
     2881 catgtttaga gcatatttta aagttaaaaa ataatatata aaatatccta taaaataaat
     2941 gactagagtt atgataattg gtacaagtaa tgaccttggt ataaactttt gtgctataga
     3001 catagcaaat aaattatgaa ctgtacctac aactaatggc attaaaaata taacttttaa
     3061 ctgttttgat attattttct caatatcttt attatttgct ccaagtttta ttaacataat
     3121 atatctttcc ttatcatcat atatatttga taattgttta aataagatta tactacctgt
     3181 acataaaaga aatactacag acaaaaatat gcctataaac agcattagac cacttaattt
     3241 tatcaagtta ttataacttt caatacttga tgtaaaatta aaaggataag taaatttcat
     3301 attttcactt actatatttt ttaattttaa agtcaaatcc agttcttttt tttcattttt
     3361 tatatcaatt aatcttatta atctagaatt tccatgtaat tttaactgat taaatacgtc
     3421 atcttttact acaattaaat caaacgtagc ttgtgaattt atttctggct ccaagatgct
     3481 tttttgtact ttaaacagat ttatatcata ctcatttgta tctttaatat gcaagtttat
     3541 tttttcaatc tcaaagtctt taaaaaatat ttttttgtat gaatcagaaa catagtacac
     3601 agattccttt gaagttaatt cttcataatt gttattctga tattgtctta attttttaaa
     3661 atcactttct ctaataatat ctacagacgt tctatcttct atataactat ttccattttt
     3721 ataatacatt tcaatattta tatctttgtc tataagttct attgttttat caaagattat
     3781 cttattatct tttttatatt tatataataa tttgtcaatt tcgttattta cataagaatt
     3841 tcctaaattt atggtataac tgtatttata attttcactt atgttcctat ctatatcgta
     3901 ataaagtgat atggtaaacc ctagcatagt tacacttgta gctattaata ttgctattac
     3961 agccaataca ctactattgc tctttaattt aaatccaagt tcagaaaatg caattaaatt
     4021 ctgtccctta taataaaaac tttttctctt cttaacagca tcaataatca tatacatagt
     4081 tgatgaaaaa aataaaaaag ttccaggtat tattgtaact aatataaaaa ctgaaagcat
     4141 aatattttca gcaataaaat aactaattga cattaaataa gaaatagtta ttaataaaac
     4201 accaagtaca cattttaact ttataaattt tttaaactta tacttttctg gatatttatt
     4261 aaataactct ataattctct tatttctgat aactatagta tttcttattc caataactat
     4321 aaatattatt aaaaatacag ctaatgtctg aactaaggcc tttatactta agttcatatt
     4381 tactactatc atttcattca ttaattttac aagcatcata gtcataagct ttgaaaataa
     4441 caatcctaaa aatataccta ttaatattgc aactataccc atcaaaaaag tttcatataa
     4501 aaatattttt cctatctgat ttttcctcat tccaagtaaa ctataagttc ctacttctcg
     4561 cctacgtcta ttgaaaaaaa atgagtttga ataatatata aataaaaata caaataccac
     4621 tattacaatt gaacttgtat taatactcat cctagttttc tctccaagtg aactcaacgc
     4681 ttcattatac tctatagatt taaaactaaa aaatacaaat acactaaata caattgaaat
     4741 aaagtacatt aaataattaa aaaaactatt ctttacattt tgcattgcaa ttctaaataa
     4801 agtcattttt attaactcct ccaattaagg aaactgtatt tactatttta ttatagaact
     4861 ctctgttact ttctcccttt acaatttctg tgaatattat tccatccttt ataaagagta
     4921 ttctattgca aaaactcgca cttatagcat catgagttac catcaatatt gttttattgc
     4981 tgtctttgtt taattttaat agacaattca acaaatccct agcagattta gaatctaatg
     5041 ctcctgtagg ctcatctgca agtactaatg atggttttgt tgctatagct ctacatacag
     5101 ctcctctttg cttttgtcca ccagaaactt cgccagggta tttatctaat atagattcta
     5161 tatttaattc ttttgaaatc tcttttattc tattttctat tactgatact ctttcatttt
     5221 ttaaagaaag aggcaacatt atattttctt ttattgtaag tgtatccaaa agattagaat
     5281 cttgaaatac aaagcctaga ttatcacgtc taaaatctgc caattcattt tgcttcattt
     5341 taatagtatt ctttccattt atataaatat ctcctgatga aggtaaatct attgtagaaa
     5401 taatatttaa aagtgttgat ttaccagcac cggaagaccc cataatacca acaaattctc
     5461 ctttataaac cttgaaagtt attcctctta gagcttcatg ttttgaacct tttcttccat
     5521 actccttttt tatattttca acatataata tttcttccat agttaataat cacctttcat
     5581 cacaattagt tatttatcaa ttctcacaaa tatattatat atattaaaat ggcttttaaa
     5641 catttaatta tattaattta aggttacatt ttcgtaagta ttaattatat ttcttcaaat
     5701 ttattgcaat tatgtttaaa atataattta tcaagtaaaa tatagttata ttaatataat
     5761 tattttaggt aataaggtag aaatatttta atttatcaag tagaatatag ttatgttaat
     5821 ataactattt tgaattagga ggtaagaatg tttaaaataa tggtagttga agatgacgtc
     5881 tcattgaaaa atatcatagc aaagtgtctt actaaatggg gacatgatgt tcatcaaata
     5941 gaaaatcttg aaaatataat agaagagttc aaaaactata acccagaatt agttttattg
     6001 gacataaacc ttccatttta tgatggtttt cattggtgta atgaaataag aaaaatttca
     6061 aaagttccta taatttttat ttcttcaaga aattctaata tggatgtaat aatgggtgta
     6121 aatttaggtg cagatgatta tatacaaaaa cctttttctg tagatgtctt agtagctaaa
     6181 gttaatgccc ttttaagaag aacttataat tttgttgata ataactcaaa tcagattatt
     6241 cacaatggtg ttactttaga tttatcaact gcaacaataa actatgaaga taatactatt
     6301 gagctaacaa aaaatgaaat caaaattctc catgagctta tgaaatataa ggggcagata
     6361 gtaagtagga ataaactcat gaaaaaatta tgggataatg attggtttgt agatgataat
     6421 acattaactg tcaatgtaaa tagaatacgc tcaaaattaa atgaaattgg tttagaagat
     6481 tttatagaaa caaaaagagg attgggttat ataatcagtt aaaacaattc taagtaggtg
     6541 aatttatgag ctttaaagat tttctcaagg ataaactagg ttttttagta tacaatttta
     6601 ctttcttaat ttttacagta tcagttatta tattttctcc tgtagatgtt tttctgactg
     6661 atactatttt atatatatta gttgtaaatg ttgtgttttt atttttatat ctatttatta
     6721 gctacatcaa gaagaacaaa tttttagata agataaaaaa tgatacattc aaaattaata
     6781 tgaatgatat agaattagct agatgtaaaa atgaagaaaa aatatacttg aacattatta
     6841 aaaatcatca atatcaatgc aataacataa taaataataa tatcgagaaa tttgaagaaa
     6901 acaaagagat tttaaatatg tgggtacatg atgtaaagat acctatagct ataataaaac
     6961 tcattcttga acaaaatgaa aatttaattg atgaaaaaat ttcagatgac atagatagtg
     7021 aaatatttag aattgaaaac tccgttgaaa aaattttata tttatcaaga ctcgaagatt
     7081 ttcataagga ttttttaatt caagaggtaa atattgaaaa aatcattaga aatattataa
     7141 aaaaatactc aaaatatttt atttcaaaaa aaattatttt agacttaaat aatttgaatt
     7201 ttaaggtttt atctgatgaa aaatggctat acttcatatt cgagcaatta ttgagtaatt
     7261 ccctaaaata ctcctcatta ggagataata tatctatcta ttgcaaaaga accaaaaatt
     7321 atttacaatt aagagtggaa gatactggtt gtggtataaa aaaggaagat ttaaatcgaa
     7381 tattcaataa gggatttaca ggtaataatg gaagaaacaa ttctaaatct acaggtcttg
     7441 ggctttattt agtaaaagaa ctttgtgata agcttggtca taaaattgat gtagattcag
     7501 agtacaacca atatacaaaa tttactatta cattcaaatg tgatttatag tatcttatta
     7561 ttgatagttt attttcatta acttatattc aacttcttat agtaattcta tatgtacatc
     7621 ccagtatata attaagtagt ttttataaaa aggaggaaga catgtctttt ctaaaaaaat
     7681 ttaaaaataa aagatttaga aataacagtt ttaaaagtaa caactttaga aatagcagtt
     7741 ttggaagtag tggcttcaag tctaaaaata aaggttttaa aaacaatccc tttaaaaata
     7801 agagattcaa aatatatgca ggaatagcag taatcatact tttaattcta ggagttcttg
     7861 cttatgttga ttcgaaaaac actgaattac aagctaatga aaattttatc gaaacatata
     7921 ctattcctga aaatgaaaaa atatttataa atgggatggt tgttcctaag caaactaagg
     7981 acttcaatat atctggagat tatgagttaa gtgatgttaa tgttacaaat ggtcaaaaag
     8041 taaatcaagg agaccttctt tttactgcta aaaatccaac tataatagca gaaatagata
     8101 gtttaaaatc acaacttagt caatacaaaa aacaaaaaat atcactttct gatattgctg
     8161 aaaataaaga tgctattgct tctataaatg cacagataac tgctttaaac tctcagatag
     8221 cttctctgga taaaaaagct tatgacagag ttactgctcc ttttgatggc acagtatact
     8281 tgaatgacca aactggaaat ccagaccaac cagtttcatt tatgactatt caaggtctag
     8341 agttttatat gaaaggacaa gcaagtgaac aagatttacc taaaatgaag attgaccaaa
     8401 tggtcaatat actcgttttt tcaactgacc aaaagcttac tggtagaata agttttatat
     8461 ctgataaacc atctactcca aatactgaaa tgggagctca gcagaataca ctatcttatt
     8521 atgatataaa catagcattt gataatcaag aaggattagt aaatggattc catcttcaag
     8581 catcacttga agtagctaat tcaagcttta aaataccagc atcttgtgta cttaaagaca
     8641 acaaacactc atatgtattt aaggatttag atggtatatt gaaaaagcaa attgtagatg
     8701 tagcaagtca aaatgatgat tttgctgtag ttagaggcgg tcttgaacaa ggcgatataa
     8761 taataaaaca ccctactaaa gaaatgaaag aaggagaccc agttcaaggc gatggcgtaa
     8821 ctgctggttc taataatgga gatactactc caaacaaaaa agtagaagaa gttactatgg
     8881 atgtgaatta atttacatat gttaattaaa ttagaaaata ttcaaaaata ttacaaagta
     8941 gggaaagatg aattacatgt tttaaaatcc ttaaatttag aaattgaatc tggagaattt
     9001 gtcatgataa tgggtaagtc tggtagtggt aaaactactt tacttaatat cttaggtttt
     9061 ctagatgtat ttgatgaagg aagatatata tttgatggaa cagatgtaac taatttgagt
     9121 gaaaatgaac gttctgtttt tagaaatatt aatattggat ttgttttcca acaatttaat
     9181 ttaatagaaa ctctaaatgt atatcaaaat gtagagttgc ctctaattta caataaagca
     9241 ctaaaaaaat ctaatagaga agaaattgtt aaagataaat taagttctgt tgggcttttg
     9301 gacaagctta agcagaaacc acttcaatta tctggtggtc aacaacagcg tgtagccatt
     9361 gcacgttgcc tagcaaatga ccctcagata atctttgctg acgaaccgac tggggcatta
     9421 gatagtgaaa ctagcagaga aattatggag cttttaacaa ggctcaacaa acaaggtaag
     9481 actataataa tggttacaca tgatcaagat ttaactaagt atgcaactaa ggttatacga
     9541 cttaaagatg gtgtgtttac ttcggaggtg taatcatgag tttattaaaa aattctttgg
     9601 ccaatttaaa aggtcacaag cttcgtgtat ttgtagcttt actctggatt ataataggaa
     9661 taacttcagt aatacttgtt agttctatag gtaatggatt tcaaaaagaa attaagaagt
     9721 ctgtaaacaa tgtaaaccct aataaaacta ctatttcgtt tgaatcagcc gataacacag
     9781 gtcttactga tgatatgagt atttttttaa aaccctttaa tgcaaaagat ttagaagaat
     9841 tatcatttgt tgaaggagta gaaagaatag ctccttcaag agatgggttt aaccttgatt
     9901 cagtttactc ttcacaagca tcttttgata aaaaaactac gtatgttgat gttggaccag
     9961 taaaaaaaga ttctaaaata aatttaattt gtggtagaga tttttcttta gatgatgaaa
    10021 aaagaaaagt aattttactt acattacaaa gtacaagtga aatttttgaa aatccagaag
    10081 atgccttagg tcatggtatc aacataaatg gaactatatt tgaaataata ggggtattag
    10141 atgattctca gcaaaaccaa gctggaggat tctttggagg ttaccaagat atgcaattta
    10201 ctacttccct agtacctaaa aaggcttttg acactttaat gagtcaaaat tcttattcaa
    10261 atgaaattta ccagttagac ttagtttctt ctaaaggcta taatgtaaat gaagttgcaa
    10321 acaatgttat agctaaatta tatgagatgc accctggtat caatggttct tatactacac
    10381 cagacccaac tgaacagaca gcttatcttg aaagcattaa ttccaatgta aacaaatatg
    10441 tatctataat aactgtagtt gcaatgtttg ttggtggtat tggtgtaatg aatataatgt
    10501 atgtatctgt tatggaaaga caaagagaaa ttggtataag acgtgctatt ggagcaaaac
    10561 ctaggtctat attatttcaa tttttagttg aagctgtttt tataacagta tgtggtggaa
    10621 ttttaggaac tatagttgga tttactgcta ctaactatgt ttctaaatat ataggttttg
    10681 aagctatacc tagcttaaat agcttatttt atgcaattgt agctactata ttgactggag
    10741 ttgtatttgg tctgattcca gcctttaaag cctctaaact agaccctata aaggcaattt
    10801 ataagtagaa attgtataaa gattttcgat ttttagatta gtttatataa aacatactta
    10861 aatatataac gcactattat atatgataga ttaggaactt aatctttcca aatataatag
    10921 tgcgttcttt cataaaaagg attctcttcc ttactatatc taaattacca aaatgttatg
    10981 ttctaattgt tcaaactaat acttccaatt ttgattaatc aatctcattc tgctaatata
    11041 caatctttta ctttcaatca ttgtacactc cgccttaaaa aaataatctt aaattaggcg
    11101 ttatatacaa tctccccatt acatattgta taattaacct ttccatataa agatttacct
    11161 ttaaacggtg aattatcagc tttagaaaca aagctttcaa ctgtccattc ttcttctgga
    11221 ttgaatataa caatgtctgc tacagcccct tcttctataa atccaatatt taaattgtac
    11281 aactttgcag gatttataga cattttttct attaactgca tcatactaag atgattttta
    11341 tgcaccaaat ttgttattcc aagagctaaa gaagtttcaa gcccaataat tccacttgga
    11401 gcttttataa actctctatc tttttcttct ttactatgag gtgcatggtc tgttgctatt
    11461 atttcaatag taccatcatt taatccctct ataatcttat ctctgtccca tttacttctt
    11521 agaggtggat tcatttttgc atttgttcca aactccaata catcttcctc agtcaatgta
    11581 aagtgatgtg gtgaagcttc tgcaactaca tttgcaccta agtattttgc aaatctaacc
    11641 atatcaacag atacacctga acttatatgt tgtatatcaa ctttagcacc agtctttagt
    11701 gccaacatac aatctctggc taccataaca tcttctgcta cacttgatgc accttttaat
    11761 cctagttttg aggctacctt tcctgcattt acacctggat ttccaactaa agaagggtct
    11821 tcttcatgaa aactaagtgg tacatccaac tcttttgcct taatcattgc ctccataatt
    11881 agattgctat ccattaaagg taatccatca tcagtaaacc ctggtacacc agctttttta
    11941 agagcttcca tatcaactaa ctctttacct tcaaaacctt tagttatagc tgctgcttgt
    12001 aaaacattta tacatgcatt ttttgacttt tctttaacat aattaaaagt atcttcatta
    12061 tctacaatag gattagtatt tgccatacat ataacagttg taaatccacc tctagcagca
    12121 gatttagctc cactttctat atcttcttta tatgtaaacc cagggtctct aaagtgtaca
    12181 tgtacatcca ctaaacctgg agcaactaca ttaccactag catctattat tttttcatat
    12241 tcatcacttt catcaaactt gcctatttta taaattttat tttcttttat aattaagtca
    12301 atattctcat ctctttgact tttagggtct attactctac catttttaat taaaatcata
    12361 ttatttctcc tttatatttt taatttatat agactcatat aatattatac attattttac
    12421 atacttaaat acaaaattac gtttgacatc aatagccttt ttaggacaaa gttcatggca
    12481 acagtaacat cttatacatt tacttaagtc tataatagca cccttagtcc ctatctctat
    12541 agtggatgca ggacaagctt ccttgcattt tccacatttt atgcaatctt gaaatcttac
    12601 cacaggcttt ggtgttataa gctttgaaat aggttcattt aaaaattttg gtagctttac
    12661 ggaaaacaat cttaaatctt tacttacatt tggaatcttg taatttttta taattaaatc
    12721 ttttatatct tcacctaaaa tttcaatatc tgaaaaatct tcttgtatat atcctctctt
    12781 aatagcacct ctaattgtag caactctatt tggaagtaaa cttataatct tacatgcaac
    12841 aacatctata gcatatggat tttgtgatgc taatgaaact cctatttctc gagtagtacc
    12901 agctgaaggt ccatcacctt ccatacctac tataccatcc ataattgtca atgttggttt
    12961 tatataatca caaatatcta aaagtacatt ttcgcaaaac aactcttctg taggaaatct
    13021 ataatgtatc tctgcttttt tcaatccagc tatgcatcca tataagtttt ttgtaccccc
    13081 agtaaaagtt gccattatat gagtctttaa tttacaaaga tttattatat aatctgaatc
    13141 tactattggt ttaataatat ccatatattt tagaacatgt gctttttcac tatgtatctt
    13201 aacatctgaa acatcataat ttaacttaat gcccagttca tttgctactt cttcaattcc
    13261 agatgcctta taaatgctct taagagaact ttgattatat ggaccaccag ggctatctgc
    13321 tattgtaata tcacaattta actctaaaag tttttcacat acaactttta caaccatagg
    13381 atgtgtagtt gtagcttctt caggcttttt tttcatcaat aaatttggtt ttataagtac
    13441 tttgcttcct tttttaacaa acttatctat accaccaata tcctctaaat ttttttcaat
    13501 agataacttt acttcttcat aattgtaagt tttacaactc ctaacagata ccgacttcat
    13561 attatctcca tccttctatc acaacagttt atttatataa tttaaaaaag gagaaaccaa
    13621 agtttctcct tttaatctat gttttaattg ttttaattat tattttccaa aatgtctgtt
    13681 taataatcct aagaatgctt taccatgtct agcttcgtct ttacacattt catgtactgt
    13741 atcatgtata gcatctaatc ctaattcttt agctctctta gctaatttta attttccatc
    13801 agttgcacca tactcagcat caactctaac tcttaagttt tcttttgtat ctgcaactac
    13861 aacttctcca agaagttctg caaatttagc agcatgttca gcctcttcaa aagctattct
    13921 cttatacgct tcagctactt ctggataacc ttctctatca gcttgtctac tcattgctaa
    13981 atacattcct acttctgtac actcaccagt aaagttagct cttaatcctt cgattatttc
    14041 tgcatctaca ccttgagcta ctcctattct atgttcatca gcccaaacca tttcgccttt
    14101 catttcttca aatttatcag ctccaacttt acatactgga cattgtgctg gtgcagcatc
    14161 tccttcatgt atatatccac atactgtaca aacaaatttt ttcataatta atttcctccc
    14221 aattttatat aattaaattt ttatttttaa gtttaataac ttgctacaag aatatatata
    14281 ccccagactt tatagcttaa acactaaaaa taaaatttat ttcctaatta attttatcac
    14341 tttgaaacac cagtatcaac caagttttga tgtcaaattt ctacataata cataatttat
    14401 ttgattaatt aggaaatagt tgtcatatta aatactttct aatgaagact cctctgaatc
    14461 tttaagtttc acttttttgc tctttaaaaa agataattta gtttctgcag ttatgattgc
    14521 aacaaatatc aagatactac caataaccaa ttttgctgta ataagctcct ttaaaattat
    14581 tatagaaaat attgtaccaa atacagcctc tgtggataat attatagctg ttctagttcc
    14641 atcaactctt ttttgacata tagtctgaaa taaaaatcca attgtggtac taaatacagc
    14701 tagatacata gttcccatgt aaccagataa ttcagcttcc atctttaatt gacctgcaaa
    14761 tgtttgaact acaacagaca ttaaaaacgc tactgtaaat tgaatagctg tcaatgccat
    14821 tgggttgtta tcttttgcaa actcacttgt aaagaatata tgaaatgcaa atccgaatga
    14881 acatataagt gttagaaaat ctccaaaatt aatagagaaa tcagcttcta aagaaagtat
    14941 cccaattcct ataagagcta ccaaactact tattattcct attttatcaa gttttcttct
    15001 ataaagtata aatcctatga acggaactat tacaacatta gctgctgtta taaacgcatt
    15061 tttagatggt gtagtgtaca taagtccaat agtttgtact gtgaatgcta gaaataaaaa
    15121 tattcctaaa atccctcctg cttttaataa ttttttaccc atattggcac gaatctgttt
    15181 aaaaaacagt aaattcataa ttatagctgc caagaaaaat cttaaagtta tgatttgtag
    15241 aggtgtaagc ccaccgtcta atgcaaattg ggttgctaca aagccacttc cccatataat
    15301 tgctataaat attagtccta tttctccaaa gtattttttc aataaagccc cctccttttt
    15361 atttttttgc aaaattataa accccctaaa cagcaagaga gtttttctat aagcattact
    15421 ataaattaat atagtaaatt ttttcagtat tttaaatcta aatttacata cattttgagc
    15481 tcaaatttat atc
//
LOCUS       DAMJXI010000083        15376 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.088, whole genome shotgun sequence.
ACCESSION   DAMJXI010000083 DAMJXI010000000
VERSION     DAMJXI010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15376
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.088"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            209..1042
                     /locus_tag="PC465_003230"
     CDS             209..1042
                     /locus_tag="PC465_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HDF2650510.1"
                     /translation="MRNKKKKINRKKLYLLLSAIVVCLAFIVVGVRVSSLNMKENEIS
                     RNAKLSSSTITDIVSNTSIEVSKGPSKSSGKIAYITIDDGPSKFTDEMIKTLNKYNVK
                     ATFFMIDGNMKEYPQQVKNIIKNGNTAGFHSVSHDIHKLYVTSTSAKEEFDTNDQTFY
                     KITGKHSKVIRIPYGSKPYTPQASYQALVDAGYKIWDWDLDTEDWRSNSSQIVQNVKN
                     HIKNRKGEDKDQLVVLMHEKKQSAEALDSVLKFLSDEGYEFAPVDQNQIPKNYWLRNL
                     E"
     gene            1135..2067
                     /locus_tag="PC465_003231"
     CDS             1135..2067
                     /locus_tag="PC465_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2650511.1"
                     /translation="MVGILSLMMVGCNKSLAKVNDVEITKEQYKKTKAVLSATNNYIN
                     GQSLDELEKTLDKKGRNKLENVIISFMVDNELLYQEAKDKGLTPSKSEVDSKYQELED
                     KMNLNTSYKEKMDKAGVDKDYLKQEISRDLAIDKNKKAFEDRINISDNDMEAYYTSHK
                     KDFNVEEVSASQILISTLDKNKKEVSKDKKEALKKKADNILTKIKNGESFESLAKKYS
                     DDKATGKNGGQLGYFTKDDKNAEFTKEVFKLKKNEVSNVFETSYGYHIVKVTDKRERQ
                     KSFNECQSLIRESILNEKYIEHIKKLNEDAKIDR"
     gene            2119..2601
                     /locus_tag="PC465_003232"
     CDS             2119..2601
                     /locus_tag="PC465_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2650512.1"
                     /translation="MFKSLKRTKVEKYIIDNKDSFYRIAYSYTKNEEDALDVVQEAMY
                     KALYSVENIKEVNYIKTWFYKILVRTSIDFIRKNRKYNNMTDIDLIDETGEYDKYTDL
                     DLRRALEELPIEYKSIIILRFFEDLKIEEVAIILDENVNTVKTRLYTALKKLKLKIEE
                     "
     gene            2613..3482
                     /locus_tag="PC465_003233"
     CDS             2613..3482
                     /locus_tag="PC465_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDF2650513.1"
                     /translation="MTSKERLNKLKDEYHKIPIPKKLDTIINHEKIENIYREKNKKVN
                     RLRFKVAIAFACIFTVLVNISPVFADNFSKIPVIGAIVEVITIKNYSLKSENYEAEID
                     IPKIRGLKDKNLEQRLNSSFMEDGKRLYHQFQERMEKIQSSKNKGYKSLSLSYSVKNN
                     SKKFLSIEMTKNEIEASSYVSKVHYTIDKKRQIVLTLPMLFKDDKYIKVISDNIKEQM
                     REQMKKDSTKSYFIDQKKDLPVEDFKTINKYQDFYFNKNEDLVICFDEYEVAPGYMGA
                     VEFVIPYKVIKDL"
     gene            3525..4280
                     /locus_tag="PC465_003234"
     CDS             3525..4280
                     /locus_tag="PC465_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDF2650514.1"
                     /translation="MTTYKKLKKSIFKIAIFSICLLVSLVDTNPIFAGSSFNETSNSD
                     TIKVLNAKSINFKQDNYEVNVSIPKIKGLKDKTLENKLNNELLQDGKKIYSEFQNKMK
                     KENNKGHRYLNVIHNVKNNSKDFLSIEMTKEEIEASSSITKKHYTVDKNRGILLNLPI
                     FFKDSRYIRAISDNIKEQMRNQIKKDDTKSYFIDQDKDSPVKDFESINKYQDFYFNKN
                     GNLVISFDEYEVAPGYMGAVEFVIPNKVIKRLR"
     gene            4322..5143
                     /locus_tag="PC465_003235"
     CDS             4322..5143
                     /locus_tag="PC465_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XdhC family protein"
                     /protein_id="HDF2650515.1"
                     /translation="MNIYEQAIRLIENNEDFAFATITSHSGSTPRETGAMMIVKNDST
                     IFGSVGGGSVEAECIKHAINVIKNRESMLYKFTLNKSDVAKLGMICGGTGEIQIDFID
                     SKLKSNIEKFNKRLKENTSKAYIFGAGHISRDVAVILSLLEFRTVVIDDREEFANHER
                     FPESEVVVLDSFENIPDFPTDENSYIIILTRGHLYDSSALEWALKREAGYIGMIGSGT
                     KIGLTYEKLMKKGFKKEELSKVHAPIGIKLNAQTPAEIAVCIAAELINCRANKEK"
     gene            5148..5909
                     /locus_tag="PC465_003236"
     CDS             5148..5909
                     /locus_tag="PC465_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HDF2650516.1"
                     /translation="MNTGSKDIDTLKVNFRGIEIKAVLVYKNRKNISIKIDPFGKITV
                     MSPPKISKKIIKDIIIEKGDWILKKSEKCKGREEVYKQRMFITGEKFLYLGEEYHLVI
                     KELLRDSVKKSNCRITINEYQIVVQTNDTSTDFIKKSLKSWYKMESERIVLERIDFLK
                     LNCEIMKQLVPASVKVKEQNKRWGSCTAQKNIYINSKISMARLDVIDYVIIHEFSHLV
                     HMNHSKKFYDLVKSIMPDYKDKENWLKINGYKIII"
     misc_binding    6070..6327
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6440..6679
                     /locus_tag="PC465_003237"
     CDS             6440..6679
                     /locus_tag="PC465_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDF2650517.1"
                     /translation="MENTVYAKLNQGIDSFLRVAMTLRRREVDIQSISMTVDNMNNSG
                     IKLIVNEEKTSLDSVLNHMKKLHDIREITVERMRH"
     gene            6983..7978
                     /gene="ilvC"
                     /locus_tag="PC465_003238"
     CDS             6983..7978
                     /gene="ilvC"
                     /locus_tag="PC465_003238"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HDF2650518.1"
                     /translation="MKMARMYYEKDVDLEVLKNKKVAVLGYGSQGHAHAQNLRDNGVH
                     VMIGLYDGSKSAQKAKEDGFEVKSVAEATKESDLTMMLMPDEKQKKVYEESVKDNLKE
                     GQTLAFAHGFNIHYNQVQPPEFVDVVMVAPKGPGHLVRNVFTKGSGVPALFAVYQDYT
                     KKATETVLAYAKGIGATRAGVLETTFKEETETDLFGEQSVLCGGISELIKLGYKTLVD
                     AGYQKEVAYFECLHEMKLIVDLIYEGGFERMRYSISDTAEYGDYVSGKRVITDAAKQG
                     MQNVLEDIQNGKFAKAWIKENEEGRENFLKTREEEYNTEIAEVGRNLRSMMSFLK"
     gene            8031..9719
                     /gene="ilvB"
                     /locus_tag="PC465_003239"
     CDS             8031..9719
                     /gene="ilvB"
                     /locus_tag="PC465_003239"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HDF2650519.1"
                     /translation="MNGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHI
                     RTSHEQGLVHAADGYARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVP
                     TSLLGKDSFQEIDITGATLSMTKHNYLVRNTKELVPTIKEAFRVANSGRKGPVLVDVP
                     KDLFLAEMDFSGEDYDLCQIDDYMDYKSDFDLDDETNIKLLNEAIDIIKESKKPVIYA
                     GGGVKSSDSEEILEKFATKIDTPVLNTLMGLGNIDRKNELSLGMVGMHGSRESNLALS
                     NSDLVIAIGARFSDRVISKSSEFAKNAKIIHIDIDPSEISKNIESNVSLVGDVKLVLS
                     LLIERVESKNNSNWKEEIKTFRKSEGVQTYEFHPQNILKKINEKYETLKKPTVVVTDV
                     GQHQMWAAKYWNFKGNKSFITSAGLGTMGFGLGAAIGTKVGNVDKNVVLVTGDGSFRM
                     NCNELATVANYNVPMLILLLNNRTLGMVRQWQKLFSNQRYSQTDINENVDYVKLVNAY
                     NIDGYKVASMEELGKALDMIDFNKPVFLQCDIDKDYDVYPIVAPNDALENLICN"
     gene            9929..10606
                     /locus_tag="PC465_003240"
     CDS             9929..10606
                     /locus_tag="PC465_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF2650520.1"
                     /translation="MFKHDKALLKEVKVERPNPQYAVLMQEQLGGANGELKAAMQYLS
                     QSFRIKDPQIKDLFLDIAAEELSHMEMVAQTINLLNGHDVDYNSVNTGEIETHVLTGL
                     SPVLINSSGAPWTANYVTVTGDLVADLLSNIASEQRAKVVYEYLYRQIDDKYVKETID
                     FLLNREEAHNALFRDALNKVKDTGSNRDFGVTEDSKLYFDLSTPGPNHDTKIDINPPS
                     FEKPLKK"
     gene            10780..12816
                     /locus_tag="PC465_003241"
     CDS             10780..12816
                     /locus_tag="PC465_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HDF2650521.1"
                     /translation="MDSNRKPNNLINEKSPYLLQHAYNPINWYSWNDEAFKKAKEEDK
                     PIFLSVGYSTCHWCHVMEKESFEDEEVAEIMNRNFVAIKVDKEERPDVDSVYMTVCQA
                     MTGSGGWPMTIIMTPDKKPFFAGTYFPKYSRYNRPGVIDLLENVSEKWNTSRDILIKS
                     GDEIIEALKDDFGVKNTEGDLSKEMLSSSVRVFKAIYDENYGGFGNAPKFPSPQNLMF
                     LMKYYSIEKDKDVLKMVEKTLDGMYRGGLFDHIGFGFSRYSTDKKWLAPHFEKMLYDN
                     AMLTIAFLDAYKITKKELYKEIAIKTIDYVVREMKDKEGGFYSAQDADSEGEEGKFYT
                     FNPLEIIEVLGEEDGIFFNNYFDITSSGNFEGKSIPNLIKNKEYERHNEKIADLSKKV
                     FEYRKERTSLHKDDKILTSWNALMIVALTKAYSTLKNDIYLEYSNKCLNFINNNLVNE
                     SGRLLARYRDGSSDYLAYLDDYAFLIWAYIELYESTFNMKYLEKALNLNESCINLFWD
                     YEKSGFYIYGKDSENLIARPKDLYDGAIPSGNSVQLYNLIRLAKITGDNRLEEMSYKQ
                     LKLYVDNVKSSPTGYSFYMLSLMFELYSTKEIICIFKEDSDLIAFKELISENFIPNAT
                     FLAKKYNEENTIIGFLNNYILKDDKTSYYVCQSNSCSQPINDLQKLKDMILGVE"
     gene            complement(13007..13573)
                     /locus_tag="PC465_003242"
     CDS             complement(13007..13573)
                     /locus_tag="PC465_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2650522.1"
                     /translation="MDYSNELKELFLMNQTYATLFTLTNKIQIEGDKYFGILTSRQYM
                     TILSILHLPEEETTLNNIARKMGTSKQNINRLVANLEKNGYVDVIPSPHDKRAINVKV
                     TDLGKKVMVTCSRTGINFMADVFHEFTKDELETLWSLLKKMYRFNGEEQDGFEEDANF
                     MEYEEIDKIKSEALEEFAKRRKRVNKND"
     gene            13861..14796
                     /locus_tag="PC465_003243"
     CDS             13861..14796
                     /locus_tag="PC465_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2650523.1"
                     /translation="MKCTNFTFKGEEGLDIYTYKWEDENIKKPKAVIQIAHGMAETAQ
                     RYETFAKVLTKNGYIVYINDHRGHGKTAKIIENVGHLAEKEGFRCLVEDMYTLTNIIK
                     KENEDLPIYLFGHSMGSFASQRYIMDYSNNLSGLILCGSNGKQGIILNLAHLIINHEI
                     KKYGRRFKSNKINNLIFGGEIIRRNEKTKFDWLSRDKEQVEKYINDPFCGVVCSCGFF
                     YDLVQGLKEIEDKENLKKVPLDIPIYIISGDKDPIGKNGNGVLRLRDRYIKLGVKDVT
                     CKLYKDGRHELLNEINREEVFEDIICWLNNKIEIL"
     gene            15262..>15376
                     /locus_tag="PC465_003244"
     CDS             15262..>15376
                     /locus_tag="PC465_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2650524.1"
                     /translation="MQIKIGKVIQRLRKERNLTQEQLAKFIGVSTPAVSKWE"
BASE COUNT         6349 a         1524 c         2689 g         4814 t
ORIGIN      
        1 aaaaaacact atataatact caattttcaa cattctatac aattatacag aaattataca
       61 gcataataat gaccgaaata acaaatttta aaaattaagc aaaacttttt gtcgaagttc
      121 aacgtctata tatatgtagt gtaaattttt gggataaaat actacaaaaa tataaatgta
      181 aaaatatagt aatattggag gtcgaacgat gagaaataaa aagaaaaaaa taaatagaaa
      241 gaagttgtat ttgcttttaa gtgctattgt agtgtgtctg gcttttatag tagttggtgt
      301 tcgcgtcagc tctttaaata tgaaggaaaa tgaaattagt agaaatgcaa aactgtcaag
      361 ttctactatt acagatatag tatctaatac atcaatagaa gttagtaaag ggccaagtaa
      421 aagttctgga aaaatagcat acataactat agatgatggt ccatctaaat ttactgacga
      481 gatgataaaa actttaaata aatacaatgt taaagcaact ttttttatga tagatgggaa
      541 tatgaaggaa tatccacagc aagttaaaaa tataattaaa aatgggaaca cagcaggttt
      601 tcatagtgta tcacatgata ttcacaagct ttatgttact agtacatcag caaaagagga
      661 atttgataca aatgatcaaa ctttttataa gataactggt aaacattcaa aagtaataag
      721 aataccttat ggaagcaaac catatacacc acaagcctct tatcaggctt tagttgatgc
      781 tggatataaa atttgggact gggacttaga tacagaagac tggagatcta attcttctca
      841 aattgtacaa aatgtaaaaa atcatattaa gaatagaaaa ggtgaagata aagaccaact
      901 tgtagtttta atgcatgaga aaaaacagag tgcagaagct ttagattcag ttttaaaatt
      961 cttatcagat gaaggttatg aatttgcgcc agtagatcaa aaccaaatac caaaaaatta
     1021 ttggttacgt aatttagagt agttaaaata taagaatatt gattgatatt tttagaaatt
     1081 gagaataaaa atgagtgagg tgtaggtata ttgaataaaa aaatttatat aggaatggtc
     1141 ggaatattgt ctttgatgat ggttggttgt aataaaagtt tagcaaaagt aaatgatgtg
     1201 gaaatcacaa aagaacagta caaaaaaaca aaagcagttt tatctgctac taataattat
     1261 ataaatgggc agtctttaga tgaattagaa aaaactttgg ataaaaaagg tagaaataaa
     1321 ttagaaaatg ttataatatc gtttatggtg gataatgaac ttttatatca agaggctaag
     1381 gataaaggac taactccaag taaaagtgaa gtagactcaa aatatcaaga actagaagat
     1441 aagatgaatt tgaatacaag ctataaggaa aaaatggaca aagcaggtgt tgataaagat
     1501 tatttaaaac aagaaatatc tagagattta gcaatagata aaaataaaaa ggcctttgaa
     1561 gatagaataa acataagtga taatgatatg gaagcctact atacaagtca taaaaaagat
     1621 tttaatgtag aagaagtaag tgcttctcag atacttatat cgactttaga taaaaataaa
     1681 aaagaagtaa gcaaagataa aaaagaagct ttgaagaaga aggcagataa tatattgact
     1741 aaaatcaaaa atggagaaag ttttgaaagt ttggctaaaa aatattcgga tgataaagca
     1801 actggaaaaa atggaggaca gctaggatat tttacaaagg atgataaaaa tgctgagttt
     1861 acaaaggaag tgttcaaatt aaagaaaaat gaagtttcaa atgtgtttga aactagttat
     1921 ggatatcata tagtcaaagt tactgataaa agagaaagac aaaaaagttt taatgagtgt
     1981 cagagtttaa taagagaatc tattttaaat gaaaagtata ttgagcatat aaaaaaactg
     2041 aatgaagatg ctaaaataga cagatagaat ttctaacagc tcaatcctag cctgtaatcg
     2101 gagggagatt ttacaggaat gtttaagagt ttaaagagaa cgaaagttga gaaatacatt
     2161 atcgataata aagactcttt ttatagaata gcatatagtt atacgaagaa tgaagaagat
     2221 gccttagatg tggttcaaga agccatgtat aaggcactat actcagtgga aaatattaaa
     2281 gaagtaaatt atataaagac atggttttat aaaattttag ttagaacgag tatagatttt
     2341 attagaaaaa accgtaaata taataatatg acagatattg accttataga tgagactgga
     2401 gagtatgata aatatactga tttggattta agaagagctt tggaagaatt acctattgaa
     2461 tacaaatcta ttataatatt aagatttttt gaagatttaa agattgaaga agtagcaata
     2521 atattggatg aaaatgtgaa tactgttaaa actaggttat atactgcttt aaaaaaacta
     2581 aaattaaaaa ttgaagagta gggataaaaa gaatgacaag caaagaaagg ttaaataagt
     2641 taaaagatga gtatcataaa attccaatac ccaagaaatt agatactata ataaatcatg
     2701 aaaaaataga aaacatatat cgagagaaaa ataaaaaagt aaatagatta agatttaaag
     2761 ttgcaatagc ctttgcatgt atatttacag tattagtaaa tataagtcct gtatttgcag
     2821 acaatttttc taagatacct gtaattggag caatagtaga agtaataact ataaaaaatt
     2881 atagtttaaa aagtgaaaat tatgaagctg agattgatat tcctaaaata cgaggtttaa
     2941 aagataaaaa cttagaacaa agattaaaca gtagttttat ggaagatgga aaaaggcttt
     3001 atcatcaatt ccaagagaga atggagaaga tacaatcatc aaagaataaa ggatataaat
     3061 ctttaagttt gagttatagt gtaaaaaata attctaaaaa atttctatca atagagatga
     3121 caaaaaatga gatagaggct tcatcatatg tgagtaaggt acattatact attgataaaa
     3181 aaagacaaat agttttgact ttgccaatgc tttttaaaga tgataagtat ataaaagtta
     3241 taagtgataa tataaaagaa caaatgagag aacaaatgaa aaaggatagt acaaaatcct
     3301 attttataga tcaaaaaaaa gacttgcctg ttgaagattt taaaacaatt aataagtatc
     3361 aggattttta ttttaataaa aatgaagacc ttgtaatttg ttttgatgaa tatgaagtag
     3421 cacctggtta tatgggcgca gttgagtttg taataccata taaagtaata aaagatttgt
     3481 aaattgaata gtagtttata tataaatctt ttaaggagga caatatgact acatataaaa
     3541 aacttaaaaa atctatattt aaaattgcta tattttcaat atgcttatta gtttcattag
     3601 tagatacaaa ccctatattt gcaggtagtt cctttaatga aacttcaaat agtgatacga
     3661 taaaggtgtt aaatgctaag agtatcaact ttaaacaaga caattatgaa gtgaatgtga
     3721 gtattcctaa aataaaaggt ttaaaagata aaactttaga gaataaatta aacaatgagc
     3781 ttttgcaaga tgggaaaaaa atttacagtg aatttcaaaa taaaatgaaa aaggaaaata
     3841 ataagggtca tagataccta aatgtaatcc ataatgtcaa aaataattct aaggactttt
     3901 tatcaataga aatgacaaaa gaagagatag aagcttcctc atctataact aagaagcatt
     3961 acactgttga taaaaataga ggaatactat taaatttacc aatatttttt aaagatagta
     4021 gatatattag agctataagt gataatataa aagagcagat gagaaatcaa attaagaaag
     4081 atgatacaaa atcttatttt atagaccaag ataaagactc gccagtgaaa gattttgaat
     4141 ctataaataa gtatcaagat ttttatttta ataaaaatgg aaatcttgtg attagttttg
     4201 atgaatatga agtagctcct ggttatatgg gagcagtaga atttgtgata ccaaataaag
     4261 taataaaaag actaagatag atatatagaa gatttttaga tagactggta aggagaatta
     4321 tatgaatata tatgaacaag caataagatt aatagaaaat aatgaggatt tcgcatttgc
     4381 tacaataacg tctcattcag gttcaacacc acgtgaaact ggagcaatga tgattgtgaa
     4441 aaatgattct actatatttg gctcagtagg aggaggtagt gtagaagcag aatgtataaa
     4501 acatgcaatt aatgttataa aaaacagaga atcaatgttg tataaattta ctctaaacaa
     4561 atctgatgtg gcaaaactag gaatgatatg tggaggtact ggagaaatac aaatagattt
     4621 tatagatagt aaattaaaaa gtaatataga aaaatttaat aagagactaa aggaaaatac
     4681 aagtaaagca tatatatttg gtgcaggtca tatttcaaga gatgttgctg tgatactatc
     4741 tcttttagaa tttagaacag tagtaataga tgatagagaa gaatttgcta atcatgaaag
     4801 gtttccagaa tcagaagtag tagttttaga ttcttttgaa aacataccag attttccaac
     4861 tgacgaaaat agttatataa ttattttaac aagaggtcat ctatatgatt caagtgcttt
     4921 agaatgggct cttaaaagag aggctggtta tataggtatg attggaagtg gaacaaaaat
     4981 tggattgact tacgaaaaac tcatgaaaaa aggttttaag aaggaagaat tatcaaaagt
     5041 acatgcacca ataggcataa aattgaatgc tcaaacacca gctgaaatag ctgtatgtat
     5101 agctgctgaa cttataaatt gtagagctaa taaggaaaaa taaactaatg aacacaggga
     5161 gtaaagatat tgatacttta aaggttaatt ttagagggat tgaaataaaa gcagttttag
     5221 tatataaaaa tagaaaaaat atttctataa aaatagatcc atttggcaaa ataactgtaa
     5281 tgagtcctcc taaaatatcc aaaaaaataa taaaagatat aattattgaa aaaggagact
     5341 ggatacttaa aaagtcagaa aaatgtaaag gaagagagga agtatataaa caaagaatgt
     5401 ttataactgg cgaaaaattt ctttatttag gtgaagagta ccatctagtt ataaaagaac
     5461 tgttgagaga ttctgtcaaa aaaagtaact gtagaataac tattaacgaa tatcaaatag
     5521 ttgttcagac aaatgataca agtacagatt ttattaaaaa atctttaaaa tcttggtata
     5581 agatggaaag tgaaagaata gtattagaga gaatagattt tcttaaatta aattgtgaaa
     5641 taatgaagca attagttcca gcgagtgtta aggtaaaaga acaaaataag agatggggaa
     5701 gttgtacagc tcaaaaaaat atttatataa actcaaaaat atctatggca agattagatg
     5761 taattgatta tgtaataata catgagttta gccatttagt acatatgaat cactctaaaa
     5821 aattctatga tttagtaaaa tccattatgc ccgattataa agataaagaa aattggctaa
     5881 aaataaatgg atataaaata ataatctaaa aacgattatt ccaaaatata ggcgtaaagt
     5941 ataaaagaag tattattgtg aaaaaaataa ataatctgaa aattttaaaa aaagtcattg
     6001 acattgtaaa tgatagggaa tataatctat attaacaaca aaacagaatt aaaatataaa
     6061 attaaaaaat taaaagcaat gacagagaca acaatactaa tagtgttatc cacagagaac
     6121 caatgttgct gagaattggt gttaacagta gtataatgat cactctggag cttttgtact
     6181 gaatattttt agtaagtaca aacgtatgtc agcgttacat gactaaggtt aaggtaatta
     6241 attacccgac ctgaaaaaag aggggtagat gtatttttta tatctacaaa taaggtggta
     6301 ccgcggaata taactttcgt ccttataagt aatatttata ttgcttataa agatgaaagt
     6361 ttttttattt taagcgatat aaataaattt aatccatata aaattaataa aaaaataata
     6421 aaaataagga gggattttta tggaaaatac tgtatatgct aaattaaacc aaggaataga
     6481 ttctttttta agagtggcta tgactctaag aagaagagag gttgatatac aatcaataag
     6541 tatgactgta gataatatga ataattcagg tataaaatta atagtaaatg aagaaaagac
     6601 atctttagat tctgtcttaa accatatgaa aaaactacat gatataagag agataactgt
     6661 tgaaagaatg agacattaat taaatatatt ttataaaact aaagataaat atgcttattt
     6721 taaaataaaa aactaaagat aaatattaaa taagaaaaat cttagattaa aatataagtg
     6781 tcattgaatt tattagttta tcacagttaa taaatttatt agtttgttgt agctaataaa
     6841 aactgaaaat tctaaaatta taattgtaag attatataaa tttagaattt aaatctgttg
     6901 aataatatta aaacaatgat aatgagtatg aatttctaat aaaaataaat atcataaaaa
     6961 taagaaaaag tattgggagg aaatgaaaat ggcaagaatg tattatgaaa aagatgtgga
     7021 tttagaggtt ttaaaaaata aaaaggttgc agttttaggt tatggaagtc aaggacatgc
     7081 acatgcacaa aatcttagag ataacggtgt acatgtaatg ataggtcttt atgacggaag
     7141 taaatcagca caaaaagcaa aagaagatgg atttgaagtt aagagtgtag cagaagctac
     7201 aaaagaaagt gatttgacaa tgatgttaat gcctgatgaa aaacaaaaga aagtttatga
     7261 agagagtgta aaggataact taaaagaagg tcagacatta gcttttgctc atggattcaa
     7321 tatacattat aatcaagtac aaccaccaga atttgttgat gttgtaatgg tagctcctaa
     7381 aggacctggt cacttagtta gaaatgtatt tacaaaggga agtggagttc ctgcactatt
     7441 tgcagtatat caagactaca ctaaaaaagc tacagagaca gttttagcat atgcaaaagg
     7501 gataggagca acaagagcag gtgttttaga aactactttt aaagaagaaa cagaaacaga
     7561 tttatttgga gaacaatcag tactttgtgg tggaataagt gaacttataa aattgggata
     7621 taaaacgctt gtagatgcag gttatcaaaa agaagtagca tattttgaat gtttacatga
     7681 aatgaaacta atagtcgacc ttatatatga aggtggattt gaaagaatga gatatagtat
     7741 aagtgacaca gcagaatatg gagattatgt atctggtaaa agagtaataa ctgatgctgc
     7801 aaaacaaggt atgcaaaatg ttttagagga tatacaaaat ggaaaatttg caaaagcgtg
     7861 gattaaagaa aatgaagaag gacgtgaaaa cttcctaaaa actagagaag aagaatataa
     7921 tacagaaatt gccgaagttg gtagaaatct aagaagtatg atgtcattct taaaataaat
     7981 atatattaaa tggattagtt tgagggaaag agtggtgtat agtagtgcgt atgaatggag
     8041 caaaggtaat tttagaatgt ttaaagaaag agggaataga cacaatattt ggatatcctg
     8101 gtggagccgt gatacctctt tatgatgctc tatacgatta ttcagatgat tttaaacata
     8161 taaggacatc ccatgaacaa ggtttagttc atgctgcaga tgggtacgca agaagtacta
     8221 atacagtagg agtttgtttt acaacatctg gtccaggagc aacaaatgcc ataactggaa
     8281 tagcaacagc ttttatggat tcttcaccta tggttgtaat ttcagggcag gtgccaacta
     8341 gtttattagg aaaagattct tttcaagaaa ttgacataac tggagcaaca ttatctatga
     8401 caaaacataa ttatttagtt agaaacacta aagaattagt tcctacaata aaagaagctt
     8461 ttagagttgc aaattcaggt agaaaaggac ctgtacttgt agatgttcca aaagatttat
     8521 ttttagcaga aatggatttt agtggtgagg actatgattt atgtcaaata gatgattata
     8581 tggattataa gagtgatttt gatctagatg atgaaactaa tattaagctt ttaaatgaag
     8641 caatagatat cataaaagaa tctaaaaagc ctgtaatata tgcaggtgga ggtgttaaat
     8701 cttcagacag tgaggaaatt cttgaaaaat ttgcaactaa gatagataca cccgtactaa
     8761 atacacttat ggggcttgga aatatagata gaaagaatga actatctctt ggaatggttg
     8821 gaatgcatgg aagtagagaa agtaatttag cactttctaa ttcagattta gtgatagcga
     8881 taggtgcgag atttagtgat agagtgataa gtaaaagttc tgaatttgct aaaaatgcaa
     8941 aaataataca catagacata gacccatctg aaataagtaa aaatatagaa tctaatgtat
     9001 ctttggttgg agatgtaaag ctagtcctta gtttattaat tgaaagggtt gaaagtaaga
     9061 ataatagcaa ttggaaagaa gagataaaga catttagaaa gagtgagggt gtacaaacat
     9121 atgaatttca tccacaaaat atacttaaaa aaataaatga aaaatatgaa acattaaaga
     9181 aacccactgt ggtagtaact gatgtcggtc aacatcaaat gtgggctgct aagtactgga
     9241 attttaaagg taataaaagt tttataacat cagcagggtt aggaactatg ggatttggtt
     9301 taggtgcagc tattggaact aaagttggta atgtagataa aaatgtagtt ttagtcactg
     9361 gtgatggaag ttttagaatg aactgtaatg aactagctac agttgcaaat tataatgtac
     9421 ctatgcttat tttactactc aataatagaa cattaggaat ggtaaggcaa tggcaaaagt
     9481 tattttccaa tcaaagatac tctcaaactg acattaatga aaatgtggat tatgttaaac
     9541 tcgtaaatgc atataatatt gatggatata aggtagccag tatggaagaa ttaggaaagg
     9601 cgctagatat gatagatttt aataaacctg tatttttgca atgtgatata gataaggatt
     9661 atgatgttta tcctattgta gcacctaatg atgcattgga aaatttgata tgtaactaaa
     9721 acttatactg aatattgata aaatttttta ttaaattttt attggtattc agttttgttg
     9781 tttagagata gattggcatt ttttattttt tcaaataaat caatgactat ataattgaga
     9841 acttattaaa ttttaattat acaatttgga atagtattac aacttaagta aataataatt
     9901 ttgaataata atttacggag gtattcatat gtttaaacac gataaagcat tattaaaaga
     9961 agtaaaagta gaaagaccaa atcctcaata tgctgtttta atgcaagaac agttgggtgg
    10021 tgcaaatgga gagttaaaag cagctatgca atacttgtcc caaagtttta gaataaaaga
    10081 ccctcaaata aaagatttat ttcttgatat agcagcagaa gagcttagcc atatggaaat
    10141 ggtagcacaa actataaatt tattaaatgg acatgatgtt gattataatt cagttaatac
    10201 aggcgaaata gaaacacatg tattaactgg tctatcacca gtcttaataa actcatcagg
    10261 agctccttgg actgctaatt acgttacagt tacaggggat ttagtagctg acttactttc
    10321 aaatatagct tctgaacaaa gagctaaggt agtttatgag tacttgtata gacaaataga
    10381 tgataaatat gtaaaagaaa caatagattt cttacttaat agagaagaag cacataatgc
    10441 tctatttaga gatgctttaa ataaagttaa agatacaggt tcaaatagag attttggagt
    10501 tacagaagat tctaaattat atttcgattt gtctactcca gggccaaatc acgatactaa
    10561 gatagatatt aatcctcctt cttttgaaaa acctttaaaa aaataatttg atatttttta
    10621 tgttgttttg ttttagtagt tataaaaatt atttactaga agaattaatt atatgaaaaa
    10681 ttaaatatgt atagttaaaa atgggtatac acttattata agtgtatatc tatttgttta
    10741 ttgcaaaaca tataataaaa taacaaatga ggtggtattt tggacagtaa tagaaaacct
    10801 aataatctaa taaatgaaaa atctccatat cttttacagc atgcttataa tcctataaac
    10861 tggtatagtt ggaatgatga ggcttttaaa aaagcaaaag aagaggataa accaatattt
    10921 ttaagtgtag gatattcaac atgtcattgg tgccatgtta tggaaaaaga atcttttgaa
    10981 gatgaagaag ttgctgaaat aatgaataga aactttgtgg caataaaagt agataaagag
    11041 gaaagacctg atgtagatag cgtgtatatg acagtttgcc aagctatgac aggtagtggt
    11101 ggatggccaa tgaccataat aatgacacca gataaaaaac ctttttttgc gggaacatat
    11161 ttcccaaaat attcaaggta taatagacct ggagttatag atttattaga gaatgtatct
    11221 gaaaaatgga atacaagcag ggatatatta ataaaatctg gagatgaaat aatagaagct
    11281 cttaaggatg attttggtgt aaaaaatact gagggtgatt tatcaaaaga gatgttgagt
    11341 tcatcagtta gagtatttaa ggctatttat gatgaaaatt atggtggttt tggtaatgct
    11401 cctaaatttc caagtcctca gaatcttatg tttttaatga aatattatag tatagaaaaa
    11461 gataaagatg tgttaaaaat ggtggaaaaa actttagatg gaatgtatag aggaggcctg
    11521 tttgatcata ttggatttgg gttttcaaga tactctactg ataaaaagtg gttggctcct
    11581 cattttgaaa aaatgctata tgataatgct atgcttacta tagctttttt agatgcgtat
    11641 aaaataacaa agaaagagtt atataaagaa attgctataa aaactataga ttatgtagtt
    11701 agagagatga aggataaaga aggtgggttt tattcagcac aggatgctga tagtgaaggt
    11761 gaagaaggta aattttatac atttaatcct cttgagataa ttgaagtttt gggtgaagaa
    11821 gatggaattt tctttaataa ttattttgat ataactagta gtggaaattt tgaaggcaaa
    11881 agtattccta atcttataaa aaataaagaa tatgaaagac ataatgaaaa gatagctgac
    11941 cttagtaaaa aggtatttga atatagaaaa gaaagaacat ctttgcataa agatgacaag
    12001 atacttacat catggaatgc attgatgata gttgctttaa caaaggcata tagtacttta
    12061 aaaaatgaca tatatttaga gtattcaaat aagtgtctta actttataaa taataatctt
    12121 gtaaatgagt caggtagatt attagctaga tatagagatg gaagttccga ctatttagca
    12181 tatttagatg attatgcttt tttaatctgg gcgtatatag agctttatga gtcaacattt
    12241 aatatgaaat atttagaaaa ggctttaaat ttgaatgaaa gctgtatcaa ccttttttgg
    12301 gattatgaaa aaagtggatt ttatatatat ggtaaagata gtgaaaattt aatagcaaga
    12361 ccaaaagatt tgtatgatgg agctattcca tcaggaaatt ctgttcaatt atacaatctt
    12421 ataagacttg cgaaaattac tggagataat agacttgaag aaatgtcata taaacaatta
    12481 aaactgtatg tggataatgt aaagagttct ccaactggct acagctttta tatgctttca
    12541 ttgatgtttg aactttattc tactaaggaa attatatgta tttttaagga agattctgat
    12601 ttaattgcat ttaaagaatt gataagtgaa aattttatac caaatgcaac ttttttagca
    12661 aagaaataca atgaagaaaa cactattata ggttttttaa ataactatat attgaaggat
    12721 gataagacta gttattacgt gtgtcaaagt aatagttgta gtcaaccaat taatgattta
    12781 caaaaattaa aagatatgat tttaggagta gaataatcat aatagcgaaa aaggagatgc
    12841 tttaaaataa aagtctaatc atctcctttt tttgtacaaa aaacagaaaa agagttccta
    12901 agaacaccta atctatgtaa tgattgtttt gttaaaaaat aaaaatgaca ttatagttat
    12961 ataaaatatt gtactacaaa aaagtagtat tatagatgcg atagtattaa tcgtttttat
    13021 ttactctctt tcttcttttt gcaaattctt caagtgcttc agatttaatt ttatctattt
    13081 cttcatattc cataaaatta gcatcttctt caaagccatc ttgttcttca ccattaaaac
    13141 gatacatttt ttttagtaaa ctccataagg tctctaattc atctttggta aattcgtgaa
    13201 atacatctgc cataaagttt attccagtcc tactacatgt caccataacc ttttttccta
    13261 agtctgtaac tttaacatta attgctctct tatcatgagg acttggaatt acatcaacat
    13321 atccattttt ttcaagatta gcaactagtc tatttatatt ttgtttactt gtacccattt
    13381 ttcttgcaat attatttaat gttgtttctt cctctggtaa atgaagaatt gataaaatag
    13441 tcatatactg tcttgaagta agtataccaa aatatttatc tccttctatt tgtattttgt
    13501 ttgtaagggt aaaaagagtt gcatatgttt gattcattaa aaagagctct tttagttcat
    13561 ttgaataatc catgaaatat atctccttta tttttagatg ttgttttgtc gaaaacagaa
    13621 tatcatgaat taattctaat gtcaatatgg tgtcaaaata tattaaagtg ttactttttt
    13681 atgtaactat taattaatta aattattgta taattttatg taaaaacttc tatgtaccaa
    13741 tgataacttc tatgaggaat taataattct taaatttttt agaaagattt tgacttgaaa
    13801 atacttgtaa tataatatat aaattaatat actgaataaa atcaatctgg agggataatt
    13861 atgaagtgta caaactttac tttcaaagga gaggaaggtt tagatatata tacatataaa
    13921 tgggaagatg aaaatataaa aaaaccaaag gcagttatcc aaattgcaca tggaatggct
    13981 gaaactgcac aaaggtatga gacttttgcc aaggtactta ctaaaaatgg ttatatagta
    14041 tatatcaatg accatagagg tcatggaaaa actgcaaaga taatagaaaa tgttggacat
    14101 ttagctgaaa aagaaggatt tagatgtctt gtagaggaca tgtatacttt aacaaatatt
    14161 ataaagaaag aaaatgaaga tttgccaatt tatctatttg gacacagcat gggttcattt
    14221 gcaagtcaaa gatatataat ggattacagt aataatttat ctggacttat actatgtggt
    14281 tcaaatggaa agcaaggaat cattctaaat cttgctcatc tgataatcaa tcatgagatt
    14341 aaaaagtatg gaagacgttt taaaagtaat aaaataaata atttgatatt tggcggcgaa
    14401 ataataagaa gaaatgaaaa gactaagttt gactggttaa gtagagataa agaacaagtt
    14461 gaaaaatata taaatgaccc attttgtgga gtagtgtgta gttgtggctt tttttatgat
    14521 ttagttcaag ggttaaaaga aattgaggat aaagaaaact taaaaaaagt gccacttgat
    14581 atacctattt acataatatc tggagataaa gaccccatag gaaaaaatgg taacggagtc
    14641 ttaagactaa gggatagata tataaaatta ggagtaaaag atgtaacttg caaactttac
    14701 aaagatggaa ggcatgaatt gttgaatgaa ataaatagag aagaagtttt tgaggatata
    14761 atttgttggt taaataataa aatagaaata ttgtaataaa aaaaatataa tgatatattt
    14821 actttaaatt tatttatata taatatttga aaagtggatt atgtatatgc aaagtagaaa
    14881 agagagagcc tagaagtgat ttttcgctac aatgccattt attgaatagg tgggtgttat
    14941 tataaataaa ttattaacac tcagtattat tatcattgta tatggaattt attttattta
    15001 aaattccttg aaagtttaaa tatagtaagt tgtagtaaag agaaaatcta aatatttaaa
    15061 tgctatttaa tgtgaatcta ttaattaggt tatacttaaa cttaattaat agattttata
    15121 tttcaagcta atgagatagg gttttagatt aaaatataac caatggttaa attacagaca
    15181 ttttgttaac tttccctcga tttactagta aatatttttt taatatactt aaattacaac
    15241 agatgtacta gggaggtata tatgcaaatt aaaataggta aagtcataca gcgtcttaga
    15301 aaagaacgaa atttaactca agaacaatta gcaaagttta taggtgtgtc aacaccagca
    15361 gtatctaagt gggaga
//
LOCUS       DAMJXI010000084        15322 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.089, whole genome shotgun sequence.
ACCESSION   DAMJXI010000084 DAMJXI010000000
VERSION     DAMJXI010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15322
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.089"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            291..980
                     /locus_tag="PC465_003245"
     CDS             291..980
                     /locus_tag="PC465_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650525.1"
                     /translation="MLQKVLWKFLKLVVGLFICSVGIVLTINCNLGLSPWDVFHQGLS
                     NHIGITIGTASIIVGSIVVIADVVLGENVGWGTVFNMLLIGFFMDLLLYSNLIPEADS
                     LFVGIIMLILGLVLLSVGMVFYMGSGLGSGPRDGLMVAIQKKTGKSLKLIRGTIEVGA
                     LIVGFLLGGKVGIGTIISAFGLGYFTQMVFGLFKLDCSKIKHRFIVDDIKFIKVYMSG
                     EKKAAVQNIVK"
     gene            1416..1955
                     /locus_tag="PC465_003246"
     CDS             1416..1955
                     /locus_tag="PC465_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2650526.1"
                     /translation="MDIGEKIKRLRTEKQLTQEELANRCELSKGFISQLENNLTSPSI
                     ATLIDILEILGTNLREFFNEIDDERISFTKEDMFETEDEDLKYKLKWLIPNSQKNEME
                     PIIITLYPGGQYKEEKPHEGEEFGYVLAGSIYVHIGEKKNKVKKGESFYFRPKANHYI
                     SNEGKTTAKVIWVSTPPSF"
     gene            1974..3017
                     /locus_tag="PC465_003247"
     CDS             1974..3017
                     /locus_tag="PC465_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2650527.1"
                     /translation="MVENIIELRDISKHYEELTVLDNFNLDIKKNEFLTLLGPSGCGK
                     TTTLKIIAGFEYADDGKVLFEGKEINNLPPYERQVNTVFQKYALFPHMDVYENVAFGL
                     KIKKTPKDVIDAKVKEVLKLVALEGFERRQVESLSGGQQQRIAIARALVNEPKVLLLD
                     EPLGALDLKLRQEMQIELKRIQKKLGITFVFVTHDQEEALTMSDTIVVMYKGKIQQMG
                     TPQDIYNEPKNSFVAKFIGESNIFDGIMIEDYKVNFCNRDFECVDKGFEKNENIEVVI
                     RPEDIKMVKPEEGMLKGKVTSTVFKGVHYEIELNENGRLWILHNTKNAEVGTELGMDI
                     YPEDIHIMRKENN"
     gene            3019..3855
                     /locus_tag="PC465_003248"
     CDS             3019..3855
                     /locus_tag="PC465_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2650528.1"
                     /translation="MKRKSFLAYPYVVWSAIFVIIPLILVVFFSFTKESGGGYAFTLE
                     NYKEVIDPIYMKVFGRSILLAGGATLICLIVGYPVAYIISKARVSRRGSLILLFILPM
                     WMNFLLRTYAWVAILGKNGLLNTFLGWFGIQPLAILYTNFAILLGMVYNFLPFMVLPI
                     YTALSKMDNDLINAAHDLGANNMTVFRKIIFPLSLPGVMSGITMVFMPAVTTFAISRL
                     LGGGKIMLVGDLIEQQFTVVGDWNFGSAISIFMMIVILISMSIMSKFGDESDKEGGGL
                     LF"
     gene            3960..4634
                     /locus_tag="PC465_003249"
     CDS             3960..4634
                     /locus_tag="PC465_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2650529.1"
                     /translation="MARWNGFTWKWYGQLLQNESIMSALYYTIVIAILASVISTIVGT
                     ISAIGIHKMRGKSKKLILNVNYLPILNTEIVTAVALMSLFVFVKMEFGFTTMLLAHIM
                     FCLPYVILSVLPKMKQLPDNIEDAAMDLGATPIYALRKVILPQIKPGIVSGFLIAFTM
                     SIDDFIISFFNAGNGVSNLSIEIYGMARRGIKPEINALSTIMFAVVLGLLLLANKKES
                     IVRGIK"
     gene            4634..5686
                     /locus_tag="PC465_003250"
     CDS             4634..5686
                     /locus_tag="PC465_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2650530.1"
                     /translation="MIKFKKAISLIAVGMMIVTLFTGCNKATDSTKVLNVYNVGDYID
                     ESLIDKFEKETGIDVQYSTYDTNEMMYQKVKSGSTHYDLVFPSDYMVEKMKNEGLLEK
                     LDFKNIPNMKYLDKSFLNPVYDKTNEYSVAYMWGTLGILYNKKEVKDPMDSWNILWNP
                     KYKGNIMMFDSVRDTIGITLKKLGYSMNSVNPKEINEAKNLLMKQKDLVLAYVNDEGK
                     DRLLGGEVAMGMLYSGDAVTLMEQNPDLDYAIPKEGTNKWVDAMCVPTTAQNKKEAEL
                     FINFLLDPENAKVNAEYIGYSTPNTGALKLLDPEITQNPVAYPSKEVLDKCETFEDIG
                     ENIKLYDKAWIELKSK"
     gene            5916..6764
                     /locus_tag="PC465_003251"
     CDS             5916..6764
                     /locus_tag="PC465_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2650531.1"
                     /translation="MNRINKKIDLLILALLVFIFLIVGIVILSIRTENKLNVFIMLAI
                     IFFIIMLTYLSNSVVGLITSSIIIFMYTSYILYNNITHNMDVEFISYMWIIATPVSSI
                     IMGNLNKSINELQNTNKKLSEQYKELVTIDSETGLRNLKIFYNDVNMEISKSIRHNTD
                     FSLMIVKLPYYGNLQTIFGENKTNKIVKYIGSNIIECTRNEDIIYSLQKDMIGILMPN
                     TSLEGSKVVKDRIKKRIKELNLDLNNRGKYVNIDVKIAFLQYKSSFGDSINFKNIVEE
                     ELQYDV"
     gene            6754..8418
                     /locus_tag="PC465_003252"
     CDS             6754..8418
                     /locus_tag="PC465_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2650532.1"
                     /translation="MMFKIFNKSLLKLVVVLSIVLTISNFSLSSYASEITSSTDKVLI
                     IYDSKKETAYNRDILNIMRTLLGRFSSDIELLKLSNYDGEINKNYYSHIFILGINENS
                     YNNDKNTKNLISSLNSYKGTICWLGYGIENLLEHKKYNLDYVGKTNNIVSVNYRGKSY
                     NLDEHYVFNIVESKDTSNKVIGSINDTLNKYPYIINDKNLFYVSKLDLDGVLFYIFCD
                     SLNDIFNIKTFDKGRIFVRIEDVHAFREPKNLVEIADYLSSKNIPFTIALIPAYVNPK
                     NHKVITLSESPEIVKAIKYMQDKGGTVILHGYTHQYKKEEVSGEGYEFWDGKKDEPLK
                     ENMKIFVKDRVLNGLRVCIENGIYPLAFEAPHYAMESEGYKELKKYFSTYMGQHQNND
                     KKFSTNTYPYIIRDTEEFNIFIPENLGYIDPEDKFTFQNIKENLDKLSIVRGFSGGFF
                     FHSYLNIEYLKNTIEYLEKQNIEFMNLRDFNNWVKVDEIQIRNNGDEIIVNYDKDLDE
                     ITKSDTRFKSISNISKILIFIVSISVLIFVIIFIYFKRIDKKKFLK"
     gene            8467..9723
                     /locus_tag="PC465_003253"
     CDS             8467..9723
                     /locus_tag="PC465_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003362983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2650533.1"
                     /translation="MRDLNVSEYLFIFSLFSIWSLLLINIILAMGGYIFYFKNFDKEI
                     KEIDEYPMISILVPAHNEAKVIGRTVESLLLLNYPKSKMELIVINDNSSDNSKEILEN
                     IKDRYNNYNFTIINTDSLTGGKGKSNALNIGYTISKGDFIAVYDADNTPDKNALRYLV
                     QTIVMNDELGAVIGKFRTRNKNKNLLTKFINIETLSFQWMSQAGRWQLFNLCTIPGTN
                     FILRRSIIEEIGGWDSKAIAEDTEISFRIYKLGYKIKLVPQSITWEQEPETVKVWIKQ
                     RTRWAKGNIYVLMKYIKNIFKQGRNKIVFDIAYFFSVYFLFLTSVIISDILFVLSISK
                     LVEISIPINFFLIWILSYLLFIIEVSISLTIEKGEATIENIFIVAIMYFTYSQLWLFV
                     AIKGMIEYLKDIIFKREVKWYKTERF"
     gene            9746..11827
                     /locus_tag="PC465_003254"
     CDS             9746..11827
                     /locus_tag="PC465_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HDF2650534.1"
                     /translation="MKKFIISIISLVLFFSNISLIYKVNADETKVKNYKFERDITIDG
                     VIGSNSTFFEVNKNWDIEEVLLHLNFSKSQILNGDVSSLTVLINNVPIKSIKLNAKTN
                     YKNTLEVLVPKDYIIQGYNEIKIKTYKTISDKICQDDSNTGNWMVIHKESYISIRYKQ
                     KKVENSINEYPYPYAEIENNHKLDTTIVVPDNMTRGETTAVFNLASAFGKITKNDDLK
                     LDVKLYSEMKNWSDDNIIYIGKPENTAEEILDILSIKEQTLLSSNCIIKQVDSPYNKN
                     KKMMVVIGSNEDDLIKASNLLIENRLSNQVLSSSVLVNKETNIKINREQKLNLGHLTL
                     KDLGYSDFLLEGAFNQQALFDVKIPTGKVLDDGSKIILNLRYSDNLDFEKSLVTVSIN
                     DVIVGSKKLDRSHSNNDKLELKIPKDIDNKNYYQVKLTFNLSIKNSNCVTRESNNPWA
                     YVSNNSYLALSTKENETLSFENYPYPFVRDDEFNDLTVIMPDYSGSQAMTWMFRLGVT
                     LGANINSHNGNINVIRGKEFSDKYKDTNIVVFGVPHNNSVIKMLNNNLNIKFDKNYSN
                     FISNDKISFIDDYGKNISTIQLIKSPYNNQKNIMVISSMNEKNLYLGMDYLLNKSKVN
                     DLKGDTLIIDEYGEVEDLAYNLKSKKEVKDSSWNMSINKTTKVFLMISFITIIVVMIL
                     SMLYIKKYKRR"
     gene            11864..12949
                     /locus_tag="PC465_003255"
     CDS             11864..12949
                     /locus_tag="PC465_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDF2650535.1"
                     /translation="MRKYMNKFKLKRSILISLIILIFIFIVYFVSIELKDRSLVNNQY
                     KGKIKSANLSVDYEINQVMKDIDKLGLNTVNVPIIINVESINSDIMSIDNNSKEKAIK
                     LIKKLNKKGISTILEAYPWIENGKLYETDWNPINKKRFFYTWQNAILNELIIDVANPL
                     DVNVLNIGSNFVHLEEYQQNWGEIIDFVQSKFDGLVTYRTNWWYTKKDDLSSKLFYEQ
                     KLNNNFFDKLDFISIAAYFELSNKPVNTVDELISALHSSTVNNRGQNIKQEIYNLYKA
                     HRKPIFFGELGFSNRESASSQPWNHTPSKAVNGEEQARCFEAYKKVFENEDWINGFSV
                     FCVGKIDDEKNFYPSKESIKVIKSWYE"
     gene            13003..14127
                     /gene="wecB"
                     /locus_tag="PC465_003256"
     CDS             13003..14127
                     /gene="wecB"
                     /locus_tag="PC465_003256"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HDF2650536.1"
                     /translation="MNDIKVMTVFGTRPEAIKVAPLIKELEKRENIKSIVCVTAQHRE
                     MLDQVIETFNINVDYDLDIMEKGQSLNDITCKILNKLPLILNKENPNIILVHGDTTTT
                     LATSLTAFYNKTLVGHIEAGLRTYDKYSPFPEELNRQLTGIIADMHFAPTNLARKNLI
                     SEGKPNNNIFVTGNTAIDALKMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKN
                     IFRAIKRIVDDFEDVQIVYPIHLNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLN
                     KSYMIMTDSGGIQEEAPSLGKPVLVLRDKTERTEGIEAKTLKLVGTNEDRIYNSVSDL
                     LINKDNYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN"
     gene            14205..15179
                     /locus_tag="PC465_003257"
     CDS             14205..15179
                     /locus_tag="PC465_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDF2650537.1"
                     /translation="MARKLIKNLGKSKSVKRVKLLFKKIFITVFIVASIVAIFNITKY
                     FEELYKVRDLKSTKIEYYMDVADEAGDGKVQLSWKALLAIDMVIHDEDLSNIKKKDTL
                     DIGEKFIVEDKNGKGEKVYKVKKFNKVLSELKFDSSQKSRARKYMKDLEYTYLGNKQL
                     DSSDEKIKFIKKLEDSAIREYIDYGILPSITIGQAILESGWGNSKLTKQSNNLFGIKA
                     DKAWKGKSVEISTSEHYNEKIVASFRSYNSLQDSVKDHSLFLINNKRYRKHGLFEAKD
                     YISQAQALENAGYSTAEDKKGNRIYAELLIDVIRSYNLQLIDNKVETK"
BASE COUNT         6217 a         1452 c         2606 g         5047 t
ORIGIN      
        1 gtttaagtat aataacttat atttagacag tttttttcat ttataaataa tataaatgaa
       61 attgaaaaca tttgaaggat agaaattggt tggataaatg tataaattac ttcaccaaaa
      121 aataatgaca aaaattgtaa ctaagttgta ataaaatggt agttatttag cataaaataa
      181 tgtatcatag aagtatatta taaaattaat aaaataagat ttttgtaaga aaactgctgg
      241 cttttgatat ttagagtgag tagttaaatt atgtttagga ggggtagaat ttgttgcaaa
      301 aagtattatg gaaattttta aagctagtag tcggtttatt tatatgttca gttggtatag
      361 tattgacgat aaattgtaac cttggattat ctccctggga tgtatttcat caaggacttt
      421 caaatcatat aggaataact ataggaactg cttctataat tgtaggttct atagtagtta
      481 ttgctgatgt cgttcttgga gaaaatgtag gatggggaac tgtttttaac atgctactaa
      541 ttggattttt tatggattta cttttatata gtaatttaat tccagaggct gatagtttat
      601 ttgtaggaat aattatgttg atattaggat tggttctttt gtctgttgga atggtatttt
      661 atatgggaag tggtttagga agtggaccta gagatggttt gatggttgca attcaaaaga
      721 aaacaggaaa atcacttaaa ttaataagag gtactataga agttggagca ttaatagtag
      781 gatttttatt aggtggaaaa gttggtatag gaactataat aagtgcattt ggattggggt
      841 atttcacaca aatggtattt ggcttattta aattagattg tagtaagatt aaacatagat
      901 ttatagtaga tgatataaaa tttatcaaag tgtatatgag tggtgagaaa aaggctgctg
      961 ttcaaaatat agttaagtaa tttaagaata aattcaacga aatgttaagt attttaaatt
     1021 aacattttgt ttagatagat aaattgaata ttaaaagaat attaaaatat gaggattgct
     1081 agaacactat aaaatataga tttctagcaa ttttttattt gttcaatatt tttttagtac
     1141 tagaagtctt attctctatt taatgaatga attaatttat aattagagat actaaacttt
     1201 atagatatta atataaacac ctttaaactg tgtattttcc aaagccttta aaatgcttgt
     1261 atttattcta aataaaaaaa taaaaaaatg tcaaaaaaac tcttgtatta tatccaaatt
     1321 ttatatataa ttacctatgt tgtttagaaa ttttaaactc aatgtttagt aaacaaaatg
     1381 tttagtaaaa taaaacagaa actaggaggt gcaacatgga tataggtgaa aagataaaaa
     1441 gattaagaac agaaaaacaa ctgacccagg aagagttagc taatagatgt gaattgtcaa
     1501 agggatttat ttctcaatta gaaaataact taacatcacc atccatagct acccttatag
     1561 atatacttga aatactaggt acaaatttaa gggaattttt taatgaaata gatgatgaaa
     1621 gaatcagttt tacaaaagaa gatatgtttg aaactgaaga tgaagattta aaatataaat
     1681 taaagtggtt aattccaaat tcacaaaaaa atgaaatgga gccaataata ataacattgt
     1741 atccaggagg acagtataaa gaagaaaagc cacatgaagg tgaagaattt ggatatgtat
     1801 tagcaggttc aatatatgtc catataggcg aaaagaaaaa taaagtaaaa aaaggagaga
     1861 gtttttactt tagaccgaaa gcaaatcact atatatcaaa cgagggcaaa actacagcaa
     1921 aagtgatttg ggtaagtacg ccaccatcat tttagaatag aggtgtttaa taattggtag
     1981 aaaatataat agaattaagg gatatatcta aacattatga agaacttact gttttagata
     2041 atttcaattt agatataaag aaaaatgagt ttctaacatt acttggacca agtggatgtg
     2101 gaaaaactac aacattaaaa ataatagcag gatttgagta tgctgatgat ggtaaagttt
     2161 tatttgaagg taaggagata aataatttgc caccatatga aagacaagta aacacagtat
     2221 ttcaaaaata tgctttattt ccacacatgg atgtttatga aaatgtagct tttggattaa
     2281 aaattaaaaa gactccaaaa gatgtaatag atgctaaagt aaaagaggtt ttgaaacttg
     2341 ttgcactaga aggttttgaa agacgacaag ttgaatcatt gagtggagga caacaacaaa
     2401 gaattgcaat agcaagagct ctagttaatg aaccaaaggt attattacta gatgaaccac
     2461 ttggagcact tgatttaaag ttaagacaag agatgcaaat agaattaaag agaatccaaa
     2521 aaaaattagg aataacattt gtttttgtaa ctcatgacca agaagaggct cttactatgt
     2581 cagatactat tgttgtaatg tataagggca aaattcaaca aatgggaaca ccacaagata
     2641 tatacaatga acctaaaaat tcatttgtag ctaagtttat aggtgaaagt aacatatttg
     2701 atggaattat gatagaagat tataaagtta atttctgtaa tagagatttt gagtgtgttg
     2761 ataaaggatt cgaaaaaaac gaaaatatag aagtagtaat aagaccagaa gatataaaaa
     2821 tggtaaagcc agaagaagga atgttaaagg ggaaagttac atctacagtg tttaaaggag
     2881 tgcattacga gatagaattg aatgaaaatg gaagattgtg gatacttcat aatactaaaa
     2941 atgctgaggt tgggactgaa ctaggcatgg atatatatcc agaagatatc catataatga
     3001 gaaaagagaa taactaagat gaaaagaaaa tcttttttag catatccata tgtagtttgg
     3061 agtgcgatat ttgtaataat tcctttaata ttagtagtat tttttagttt tacaaaagaa
     3121 tcaggtggag gttatgcctt tacacttgag aattataaag aagtaattga ccctatatat
     3181 atgaaagttt ttgggcgttc tattctttta gcaggaggag ctacattaat atgccttata
     3241 gttggttatc cagtggcata tataatttca aaggctcgtg taagtagaag aggttcatta
     3301 atattattgt ttattcttcc tatgtggatg aactttcttt taagaacata tgcatgggtt
     3361 gctatattag gaaaaaatgg acttttaaat acatttttag gttggtttgg aatacaacca
     3421 ttagcaattt tgtatactaa ttttgccata cttttaggta tggtgtataa ctttttacca
     3481 tttatggttc ttccaatata tacagcacta tcaaagatgg ataatgattt gataaacgct
     3541 gctcatgact tgggtgcaaa taatatgaca gtttttagaa aaattatatt tcctttgagt
     3601 ttgccaggtg taatgtctgg aataactatg gtatttatgc cagcagtcac tacttttgca
     3661 atatcaagac tgttaggtgg aggtaaaata atgctggttg gagatttgat tgaacaacag
     3721 tttacagttg ttggagattg gaactttggt tcagctatat cgatatttat gatgatagta
     3781 atattaatat ctatgtctat aatgtcaaaa tttggagatg aatctgacaa agaaggcggt
     3841 gggttactat tttaaaatta aagaaaataa cttctaatat atatttagca ttagtattct
     3901 tatttttgta tgcacccata tttgctttgg tactattttc tttcaatgat tcaaaatcaa
     3961 tggcaagatg gaatggattt acatggaagt ggtatggtca attacttcaa aatgagagta
     4021 taatgagtgc tttatattat actattgtaa tagctatatt agcatctgta atatctacaa
     4081 tagtaggaac tataagtgct ataggaatac ataagatgag aggtaagagt aagaaattaa
     4141 tactaaatgt aaactatctt cctattttaa atacagagat agttacagca gtagctctta
     4201 tgagtctgtt tgtatttgta aaaatggaat ttggatttac aacaatgcta ttggcacaca
     4261 taatgttttg tttgccatac gttatacttt cagttttgcc aaaaatgaag caattacctg
     4321 ataatataga agatgcagct atggacttgg gagcaacacc tatatacgct cttagaaaag
     4381 taattttacc acaaataaaa ccaggtatag tttctggatt tttaattgca tttactatgt
     4441 caatagatga ctttataata agtttcttta atgctggaaa tggtgtaagc aatctttcta
     4501 tagaaatcta tggaatggct agaagaggta taaaacctga aataaatgca ttatcaacaa
     4561 taatgtttgc agtggttcta ggtttacttt tactagctaa taaaaaagaa tctatagtaa
     4621 gggggattaa ataatgatta agtttaaaaa agcaatatcc cttatagctg taggtatgat
     4681 gatagttact ttatttacag gatgtaataa agcaactgat tctacaaaag ttttaaatgt
     4741 atataatgtt ggagattata tagatgagtc tcttatagat aagtttgaaa aagaaacagg
     4801 aatagatgtt caatattcaa cttatgatac taatgaaatg atgtatcaaa aagtaaagag
     4861 tggtagtaca cactatgatt tagtatttcc ttcagactat atggtagaga aaatgaaaaa
     4921 tgaaggtctt ttggaaaaat tagattttaa gaatatacct aatatgaaat atttagataa
     4981 gagtttttta aatcctgtat acgacaaaac taatgaatat agtgttgcat atatgtgggg
     5041 aactcttgga atattgtaca ataagaaaga agttaaagac cctatggata gctggaatat
     5101 actttggaat ccaaagtata agggaaatat aatgatgttt gactctgtta gagatactat
     5161 agggataact cttaaaaaat taggatatag catgaatagt gtaaatccaa aagaaataaa
     5221 tgaagctaaa aatcttttaa tgaaacaaaa ggatttagta ttggcttatg taaatgatga
     5281 gggtaaggat agattacttg gtggagaagt ggcaatgggt atgctgtatt ctggagatgc
     5341 agttacacta atggagcaaa atcctgacct tgattatgct atacctaaag agggaactaa
     5401 taaatgggta gatgctatgt gtgtacctac aacagcacaa aataagaaag aagctgagct
     5461 gtttataaac tttttattag acccagagaa tgcaaaagta aatgctgagt acattgggta
     5521 ttcaacacct aatacaggag cactaaaatt attagaccca gaaataactc agaatcctgt
     5581 tgcatatcca tctaaagaag tacttgataa atgtgaaact tttgaagata ttggtgaaaa
     5641 tataaaatta tatgacaagg cttggataga gttaaaatca aaatagggtc ttgttggttt
     5701 aagtaaattt acttaataaa tacttaataa aactgttctt ttttagaaaa tttattttct
     5761 aattattgaa cagttttatt ttttgtttaa gttatattca tatgcaattt aaatagttta
     5821 ttaataaatg aaaacttatt tgtataatga ctttaataat aattagaaaa actgggcaac
     5881 ttaatagaat aattggaggt gtaaatttat aaaaaatgaa taggataaat aaaaaaatag
     5941 atttattaat attggctttg ctcgttttta tatttttaat tgttggaata gtaatactat
     6001 cgattaggac agaaaataaa ttgaatgtgt tcataatgtt agcaataatt ttttttataa
     6061 taatgttaac ttatttatca aattcagtag tggggttgat aacaagttca ataattatat
     6121 ttatgtatac atcctatatt ttatataaca atattactca caatatggat gttgaattta
     6181 tatcatatat gtggataata gcaacaccag tatcttcaat tataatgggt aatctgaaca
     6241 aaagcataaa tgaattgcaa aatacaaata aaaaactatc tgaacagtat aaggaattag
     6301 tgactattga tagtgaaact ggacttagaa atttaaagat tttttataat gatgtaaata
     6361 tggagataag taaatctatt agacataata ctgatttttc tcttatgata gtaaaattac
     6421 catactacgg aaacctacag actatatttg gtgaaaacaa aactaataaa atagtaaaat
     6481 atattggttc aaatattata gaatgtacaa gaaatgaaga tataatttat agtttacaaa
     6541 aagatatgat agggatacta atgccaaata catctttgga aggttcaaaa gttgttaaag
     6601 acagaataaa gaaaaggata aaagaattaa acttagattt aaacaatagg ggaaaatatg
     6661 taaatataga tgtcaaaatt gcatttttac aatataagag tagttttgga gatagtataa
     6721 attttaagaa tatagttgaa gaggaacttc aatatgatgt ttaaaatatt taataaaagt
     6781 ctattaaaat tagtagttgt attatcaata gtactgacaa tatcaaattt tagcttatct
     6841 tcatacgcat cagaaattac ttccagcaca gataaggtat taatcatata tgattctaag
     6901 aaagaaacag cttataatag agatatttta aatattatga ggactctatt gggaagattt
     6961 agttcagata tagagctatt aaaattgagt aactatgatg gtgagataaa taaaaattat
     7021 tacagtcata tatttatttt aggaatcaat gaaaactcat ataataatga taaaaacact
     7081 aaaaacttga ttagttcctt aaattcatat aaaggaacta tatgttggtt aggatatggt
     7141 atagaaaatc ttttggaaca taaaaaatac aatttagact atgtaggaaa aacaaacaat
     7201 atagttagtg taaattatag aggtaaatca tataacttgg atgaacatta tgtttttaac
     7261 attgtagaat caaaagatac aagtaataaa gtaataggaa gtattaatga taccttaaat
     7321 aagtatccat atataataaa tgataaaaat cttttttatg tatcaaaatt agatttagat
     7381 ggagttttat tttatatatt ttgcgattca cttaatgata tttttaacat taagacgttt
     7441 gataaaggac gtatatttgt aagaatagaa gatgtacatg cttttagaga accaaaaaat
     7501 cttgtagaga tagcggatta tttaagtagt aagaatatac catttacgat tgcattaata
     7561 ccagcatatg taaatcctaa aaatcataaa gtaataactt tatcagaaag ccctgaaatt
     7621 gtcaaagcaa taaaatatat gcaagataaa ggtggaactg tgatattgca tggatatact
     7681 catcaataca agaaagaaga agtttctgga gaagggtatg aattttggga tggtaaaaaa
     7741 gatgaaccct taaaagaaaa tatgaagata tttgtcaaag atagagtttt gaatggtctt
     7801 agagtatgta tagagaatgg aatttatcct cttgcatttg aagcgccaca ttatgcaatg
     7861 gaatcagagg gatataaaga attaaaaaaa tatttttcta cttatatggg gcaacatcaa
     7921 aataatgata aaaaatttag cacaaataca tatccttata ttattaggga tacagaggag
     7981 tttaatatat ttatacccga aaatttagga tatatagacc cagaagataa gtttactttt
     8041 caaaatataa aagaaaattt agataaatta tctattgtaa gaggttttag tggagggttc
     8101 ttctttcatt catatttaaa catagagtat ctaaaaaaca caatagaata tttagaaaaa
     8161 cagaatatag aatttatgaa tttaagagat tttaataatt gggtaaaagt tgatgaaata
     8221 caaataagaa ataatggaga tgaaattata gtcaactatg ataaggattt agatgaaata
     8281 actaaaagtg atactagatt taaatccata tccaatatta gtaaaatttt aatattcata
     8341 gtatctataa gtgttttaat atttgtgatt atatttatat attttaagag aatagataaa
     8401 aagaaatttt taaaataaat gattttatat tagaatcaat attttaaaat attttaggag
     8461 aaatttatga gagatttaaa tgtatcagag tatttgttca tatttagtct gtttagtata
     8521 tggtctttat tgcttataaa tattatttta gctatgggtg gatatatatt ttattttaaa
     8581 aactttgata aagaaataaa agaaattgat gaatatccta tgatatcaat acttgttcct
     8641 gctcataatg aagctaaagt gataggtaga actgtggagt ctttgctatt actcaattat
     8701 cctaagagta agatggaact tattgttata aatgacaatt cttctgataa tagtaaagaa
     8761 attttagaaa atataaagga taggtacaac aattataatt tcactataat aaatacagat
     8821 agtttaacag gtggaaaagg aaagtctaat gcattaaata ttggatatac gatttcaaaa
     8881 ggagatttta tagctgttta tgatgcagat aacacaccag ataaaaatgc acttagatat
     8941 ttagtacaaa ctatagtaat gaatgatgaa ttaggtgctg ttattgggaa atttaggact
     9001 cgaaataaaa ataaaaacct attaaccaaa tttataaaca tagaaacatt aagctttcaa
     9061 tggatgtcac aagctggtag atggcaactt tttaatctat gtacaatacc aggaactaac
     9121 tttatattga ggagaagtat catagaagaa attggaggat gggatagtaa agcaattgca
     9181 gaagatacag aaataagttt taggatatat aaattgggat acaagataaa gcttgtacca
     9241 caatctataa catgggaaca agagccagaa actgttaagg tgtggataaa gcaacgtact
     9301 agatgggcaa aagggaatat atatgtatta atgaaatata taaaaaatat atttaaacag
     9361 ggaagaaata agattgtgtt tgatatagct tacttttttt ctgtatattt tctattttta
     9421 acatctgtaa ttatatccga tattttattt gttttaagta tatctaaact agtagaaatt
     9481 tctattccaa ttaacttttt tctaatatgg atactatctt atcttttatt tattatagaa
     9541 gtgagtataa gccttactat agaaaaaggt gaagcaacaa ttgaaaatat attcatagtt
     9601 gcaataatgt attttacata ctctcaacta tggctgtttg tagctataaa aggaatgata
     9661 gagtatctaa aagatataat ttttaaaaga gaggttaaat ggtataaaac agaaagattt
     9721 tgattcatgt acaggaggaa ttaacatgaa aaaatttatt atatcaatta tatctttagt
     9781 attgtttttt tcaaatatat cacttatata caaagtaaat gctgatgaga ctaaagttaa
     9841 aaattataag tttgaaagag atataactat tgatggtgtt ataggaagta atagtacttt
     9901 ttttgaagta aataaaaatt gggatattga agaagtttta ttgcatctta attttagtaa
     9961 gagccaaata ttaaatggag atgtttcaag tttaactgta ttgataaata atgtaccaat
    10021 aaaatctatt aaattaaatg ctaagacaaa ttataaaaat acattagaag tattagttcc
    10081 aaaagattat ataattcaag gatataatga aataaaaata aaaacataca aaacaatatc
    10141 tgataaaatt tgccaagatg attccaatac tgggaactgg atggttattc acaaagaatc
    10201 atatatatca attagatata agcagaaaaa ggtggaaaac tcaataaatg aatatccgta
    10261 tccatatgca gaaattgaaa ataatcataa attagataca actatagtag taccagataa
    10321 tatgactaga ggagagacta cagcagtgtt taatttggca tcagcatttg gaaaaataac
    10381 aaaaaatgat gatttaaagt tagatgttaa attatattca gaaatgaaaa attggtcaga
    10441 tgataatatt atatatattg gtaaacctga aaatacagca gaagaaattt tggatatttt
    10501 aagtataaag gaacaaaccc tattatcttc aaactgtata atcaagcaag tagattcacc
    10561 atacaataag aataagaaga tgatggtggt aattggtagt aatgaagatg atttaataaa
    10621 ggcatcaaat ttattaatag aaaatagact ttctaaccaa gttttatcat catcagtact
    10681 tgtaaacaaa gagactaata taaaaattaa tagggaacaa aaattaaatt taggtcattt
    10741 aacattaaaa gacttaggat attctgactt tttgttggaa ggagcattta atcaacaagc
    10801 tttgtttgat gtcaaaatac caacgggtaa ggtattagat gatggttcaa agattatctt
    10861 aaatttaaga tattctgaca atttagattt tgaaaaatct ttagttacag tgtctataaa
    10921 tgatgttatt gtgggaagta aaaaattgga taggtcacat tctaataatg ataagttaga
    10981 attaaaaata cctaaagata tagataataa aaactattat caagttaaat tgacatttaa
    11041 tttgagtata aaaaattcga attgtgttac tagagagagt aataatcctt gggcatatgt
    11101 atcaaataat tcttatttgg cgttatctac gaaagaaaat gaaaccttat cttttgaaaa
    11161 ttatccgtat ccatttgtta gagatgatga atttaatgat ttaactgtga taatgccaga
    11221 ttattcaggg tcacaagcta tgacctggat gtttagatta ggtgttactt taggtgcgaa
    11281 tataaattca cataatggaa atataaatgt aattagagga aaagaattta gtgacaagta
    11341 taaggatact aatattgtag tttttggagt gccacataat aattctgtta taaagatgtt
    11401 aaataataat ttaaatataa agttcgataa aaattactcc aattttatat caaatgataa
    11461 gataagcttt attgatgatt atggaaaaaa tatttctacc attcaattaa taaaatcacc
    11521 atataataat caaaaaaata tcatggtaat tagttcaatg aatgaaaaaa acttatattt
    11581 aggaatggat tatttgttga ataaaagtaa agttaatgat ttaaaaggag atacattgat
    11641 aattgatgaa tacggagagg tagaagattt agcttataat ttaaaatcta agaaagaagt
    11701 aaaagattca agttggaata tgagtataaa taagacaact aaagtatttt taatgatttc
    11761 ttttattact ataattgtag tcatgatatt atcaatgcta tatataaaaa aatataaaag
    11821 aagataatat gataaattta ttattttaaa agaggtatat aatttgagga aatatatgaa
    11881 taaatttaaa ttaaaaagaa gtattttaat ctcattaata atcttaattt ttatatttat
    11941 agtttacttt gtaagtattg agttaaaaga taggagtcta gtaaataatc aatataaagg
    12001 taagattaaa tcggccaatt tatctgtaga ttatgaaata aatcaagtta tgaaggatat
    12061 agataaattg ggattgaata cagtaaatgt acctataatt ataaatgtag agtccattaa
    12121 ttctgatatt atgtcaatag ataataatag taaagaaaag gcaattaagt taataaaaaa
    12181 attaaataaa aaaggtattt caacaatatt agaggcatat ccatggattg aaaatggaaa
    12241 attgtatgag actgactgga accctataaa taaaaaaaga tttttttata cttggcaaaa
    12301 tgccatatta aatgaactta taattgatgt agcaaatcca ctggatgtaa atgttttaaa
    12361 tattggttct aattttgtac atttggaaga atatcaacaa aattggggtg aaataataga
    12421 ttttgtacaa tccaaatttg acggtcttgt aacgtacaga actaattggt ggtatacaaa
    12481 aaaagatgat ttaagtagta agttgtttta tgaacaaaag ttgaacaata atttttttga
    12541 taagttagat tttatatcta tagcagcata ttttgagtta agtaataaac ctgttaatac
    12601 agtggatgaa ttaatttctg ccttacactc atctactgta aacaatagag gacaaaatat
    12661 aaaacaagaa atatataacc tttataaagc tcatagaaaa cctatatttt ttggagaatt
    12721 aggtttttca aatagagaaa gtgcaagttc tcagccgtgg aatcatactc cttcaaaagc
    12781 tgtaaatggc gaagaacaag caaggtgttt tgaggcatat aagaaagttt ttgaaaatga
    12841 agactggata aatggttttt ctgtgttttg tgtaggtaaa atagatgacg aaaaaaattt
    12901 ttacccatca aaagagagta taaaagttat taagtcttgg tatgaataat tttgaaagtg
    12961 tagaatttat atagattaaa tagatgatta ggagagatat aaatgaatga catcaaggtt
    13021 atgactgtat ttggaactag acctgaagct atcaaagtag cacctttaat aaaggaactt
    13081 gaaaaaagag agaatataaa aagtattgtt tgcgttacag ctcaacatag agaaatgctt
    13141 gaccaagtta tagaaacctt taatataaat gtagactatg atttggatat aatggaaaaa
    13201 ggacaaagcc tgaatgatat aacatgtaag attttaaata aacttccgtt gattttaaac
    13261 aaggaaaatc caaatataat attggtacat ggagatacaa ccacaactct agctacaagt
    13321 ttgactgcat tttataataa aactcttgtt ggtcatatag aagctgggct tagaacctat
    13381 gataaatatt ctccttttcc agaggagtta aatagacaac ttacaggtat tattgctgat
    13441 atgcactttg ctcctactaa tttggctaga aaaaacttga tttctgaagg aaaacctaat
    13501 aataatatat ttgtaactgg taatactgct attgatgctt taaagatgac aataaaagaa
    13561 aactataatc atcctataat tgatgagatt ggtaacgata ggatgatttt gttaacctct
    13621 cacagaagag aaaatttggg taaacctatg aaaaatatat tcagagctat aaagcgaata
    13681 gtagatgact ttgaagatgt acagatagta tatcccatac atttaaatcc taaaatacga
    13741 actatagctg atgagatatt tggaaaattt cctgaaaaaa ttcatattat agagccttta
    13801 gatgtagctg attttcataa ctttttaaat aaatcttata tgataatgac tgatagtgga
    13861 ggaatacagg aagaagctcc atcattaggt aagccagttc ttgtgttgcg tgataaaaca
    13921 gaaagaacag aaggaattga agcaaagaca cttaaattag taggtactaa tgaagataga
    13981 atatataatt cagtgagcga tttattaata aataaagata actatgttca gatgagtaaa
    14041 gcatctaatc catatggaga tggaaatgca agcaaatata tagtggatat aataattaaa
    14101 aaatttaatt gcaaatattt aaattagata aggcctaaaa cattaactaa ttgatataag
    14161 atttatgata atattaagga atacaatttt taagggggag taatatggct agaaaattaa
    14221 taaaaaattt gggtaaaagt aaaagtgtaa agagagtgaa acttttattt aagaagattt
    14281 ttattactgt attcatagta gcaagtatag ttgctatttt taatataacg aaatattttg
    14341 aggaattata caaagtaagg gatttaaaaa gtactaaaat tgaatactat atggatgtgg
    14401 ctgatgaagc aggagatgga aaggtccaat taagttggaa ggccttactt gctatagaca
    14461 tggtaataca tgatgaagat ttaagtaata taaaaaagaa agacacattg gatatagggg
    14521 aaaagtttat agtagaagat aaaaatggta aaggcgaaaa ggtgtataag gtaaaaaagt
    14581 ttaataaggt attaagcgaa ttgaaatttg actcttctca aaaaagtaga gcaagaaaat
    14641 acatgaaaga tttagaatac acataccttg gaaataaaca attagatagt agtgatgaaa
    14701 aaattaaatt tataaagaag ttagaagact cagctataag agaatatatt gattatggaa
    14761 tattgccctc tataacaatt ggacaagcta tattagaatc tggttgggga aattctaaac
    14821 ttacaaaaca gagtaataat ttatttggta taaaagcaga taaagcatgg aaaggaaaaa
    14881 gtgtagaaat ttcaacttca gagcattata atgaaaaaat tgtagctagt tttaggtcgt
    14941 ataattcatt acaagattct gtcaaagatc acagtttatt tttaattaat aataaaagat
    15001 atagaaaaca tgggttgttt gaggcaaaag attatattag tcaagctcaa gcattagaaa
    15061 atgcaggata tagtacagca gaagataaaa aaggaaatcg tatatatgca gagctattaa
    15121 tagatgttat taggagttat aatttgcaat tgatagataa taaagttgag acaaaataat
    15181 tgttaacttt atatgaggag ataacaagat aagatttttt tctacaaaaa gaatagaaaa
    15241 attgtaaaaa aaactaaaaa aatgtattga cttgttattt aaaaggtgat attattatta
    15301 ctgtactcga aagagaacaa aa
//
LOCUS       DAMJXI010000085        14998 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.090, whole genome shotgun sequence.
ACCESSION   DAMJXI010000085 DAMJXI010000000
VERSION     DAMJXI010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14998
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.090"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(57..593)
                     /locus_tag="PC465_003258"
     CDS             complement(57..593)
                     /locus_tag="PC465_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HDF2650538.1"
                     /translation="MEYKSPVYGIIAVPIEKIESNDYNPNAVAPPEMQLLYKSIKEDG
                     YTMPIVCYYNEEKDKYIIVDGFHRYRVMLENEDIYDRENGLLPVSVIDKSLDERMAST
                     IRHNRARGSHNVDLMSKIITELCEIGKSDEWISKHLGMEVDEILRLKQITGLAYLFKD
                     KEFGNAWIPFGSDIEEEN"
     gene            complement(611..1924)
                     /locus_tag="PC465_003259"
     CDS             complement(611..1924)
                     /locus_tag="PC465_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HDF2650539.1"
                     /translation="MDKRYLESDVFEAFQERLSYLFNEFDYIYVSFSGGKDSGLLLNL
                     VLDYKRKNNISSKIGVFHQDFEAQYSLTTEYVEKVFEDNIEDIEPYWVCLPMATRTAV
                     GNYEMYWYPWDDEKEELWVREMPVKEYIINQKNNPFTYYKYKMRQESLAKQFGRWIRD
                     IHEGAKVVCLLGTRAAESLQRYCSIVNKQHGYKGKCWITKEFKNVWTASPIYDWEIED
                     IWLAHYKFDYDYNKIYDLFYKAGVAPRKMRVASPFNDSAKESLNLYRILDPDVWVKLV
                     ARVQGVNFTSIYGKTKAMGYRSVKLPYGHTWKSFTYFLLDTLPENIRNSYIKKFSTSI
                     EFWQNTGGGLSEIVIRELLRKGYKIELNGVSNHTKDKKSRVIFLDDIPDDTDDIKFTK
                     DIPSWKRMCYCILKNDHMCRFMGFGPTKEQRIRTEYIKKKYEKIH"
     gene            2279..2719
                     /locus_tag="PC465_003260"
     CDS             2279..2719
                     /locus_tag="PC465_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HDF2650540.1"
                     /translation="MYERMLDKSNKPCLSQIIEYIGKDGYARLCKLETYLKTQYNLSR
                     ELRFPFGNNYGWGYKYSHKSFHLFYAFFEKGAFTVLIQIGDKQVPAVEKTLVALTPKA
                     KELWVTRYPCGNNGGWIKYRILEDADLLDIIQYIRAKKSPPKQN"
     gene            complement(2904..3092)
                     /locus_tag="PC465_003261"
     CDS             complement(2904..3092)
                     /locus_tag="PC465_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650541.1"
                     /translation="MNKNNNLVIICMFIGMILGMAIGCAIGISKGNVGITMCYGLIFG
                     MIIGICIGTVIKNSNKKE"
     gene            4126..4521
                     /locus_tag="PC465_003262"
     CDS             4126..4521
                     /locus_tag="PC465_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650542.1"
                     /translation="MNILKMKKTGIFLGGVLFGTVGVKILSSDCVKKTCTRATAGALK
                     VKDSVLETTTKIQENVEDILAEAKEINEQEDLSTSKVNVVQDTLKCEQEVLKTETIKT
                     VEDTNSNSIKCEEIKDNVIEEKNSTCTTE"
     gene            4564..6663
                     /locus_tag="PC465_003263"
     CDS             4564..6663
                     /locus_tag="PC465_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HDF2650543.1"
                     /translation="MNFYIKHEIRGRIRFDLQLGKLNNKQSDTLLYYLTSINGITKAK
                     VYDRTGDAVIYYTGEREYIIREITKFSFNNSKIENLVPEHTSRELNNYYRDKLANKLL
                     VKSISKIFFPKSLRFFLIGLHSIKYFKKGLSSLLNKKIEVSVLDATAIGISIFRKDIN
                     TAGSVMFLLGIGELLEEWTRKKSIDDLAQSMSLNIEKVWLRKGDTEILIPISEIKEGD
                     LVSVTMGNMIPLDGVIVSGETMVNQASLTGESLAVNKKEGSYIYAGTVIEQGNIVMCV
                     KEKAGTTRFQKIVTMIEESEKLKSSVESKFEHLADTLVPYSFLGSILTYAITRNPIKS
                     LSILMVDFSCALKLSIPISVLSAMRECNNNNITVKGGKFLEGVACADTIVFDKTGTLT
                     KAQPTVSDIITFQNYNKEDMLRLAACLEEHFPHSIANAVVYEAEKQGLSHKEMHTEVE
                     YIIAHGISTKVDDKKVVIGSKHFVFEDEKCTIPDGEEDKYNNLSDEYSHLFMAISGKL
                     SAVICINDPLRKEAKYVISNLRECGIKKIVMMTGDSEKTAKSIASKVGVDEYYSEVLP
                     EDKANFVKSEKLKGRKVIMIGDGINDSPAISESDVGIAMSEGAEIAREISDITISADN
                     LNNLIVLKQISNKLMKRVDLSSKFIIGFNLGLILLGVGGFVRPSTSAFLHNASTVGIS
                     LNSMTNLLENTNTYNYH"
     gene            complement(6888..12098)
                     /locus_tag="PC465_003264"
     CDS             complement(6888..12098)
                     /locus_tag="PC465_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HDF2650544.1"
                     /translation="MANKLYSEIVNLLEEGRDELRKYDLKEKSILLFLGASGVGKSTC
                     INYLKGCVMEEKTDEETGQIYITAKDSAVEIGNGVYSKTLCPEVVDIANRDFSLCDCP
                     GFFDNRGAEYMIAGAMLVRETISTSSKVKGMVVILDYQSLLDSRHTLLIETGKNLKDM
                     LGDYAKYKENFFFLINKIPKTLIGNVTEEKIRNILEKAKEDLDSQEKDYDGCKELVYL
                     LNVALSDGVSIKLCNPLDKQPEKLLNEMKNLPETFEKTDLGLMLTASCKIEIQKAVDV
                     TYKDLEKLLVPYIESVKKGMEDSISILSSINSLKDKKIQLDKMYTDLCSRTNNMKELM
                     EFVQELSYGDGVQKVNILEETRLLLELNSYCSETHIVGLSELLKSLLKNTLEDTLKDI
                     KYWIAEEEYREEEAKRLEDAEYRIEKIQSCTYIKSYEKENVLSIYIPIPKVNLSDLTK
                     IISGYQLNILSSIYMYGDCELKIDCNMEKEVFSGKNIVLLTEKLHIPEGTYSINVSGK
                     DAEKLVGESSIYDGMNGRNGNNAGTSGDIILSFKEIEKRGELKLYVDGGRGGNGQDGK
                     KGDTGITGEAGANAKIGSKKESKEFANVKGTKYYVVKAEKGKQGGTGGTGGNGGNAGL
                     GSKSGQVYLLGKAPLLKSAISKKDGNHGLAGKGGSGGAGGAGGLGGIRGIYEETIRYI
                     GTSPPMDDSDRNYYYFDRYVFNHALNQKQAVDDGEKLNTLYEEHKDWTISKREDSGSA
                     GAEGKDGHSGDALKEKELLKQEYSLSIDTFFYEFFERFGFSGIKGYRNLRLLCAVGIL
                     EADILEFSHIYEIFYAVEKIEMQLNREILQKYYSFEKKNKAVLSLDDMNTKKEFYKEA
                     KEIYEYLINKLMQSDRIESFVGKNQNFSEWSMILFALEQKTAFYVQMIEESEIGGNRV
                     TDIRSLTDYLDKTLRELEQGKKDELKEGYFNTYKESILTQIESGNQQIEVLKNELENK
                     MLSVNAKMNLLIQEIIKMKEDEQEDIEELKKKQAKLEEQMKTQLILSGIQSALSLLTA
                     FSGVGQACLGAFDSAKSLKENLSAKEEEYKWTNRMVDFSDFKLDSDGMRFVLGEQLSE
                     DRKNALDKMTYNLAGVDEERRTKFDQIKEIIVKSIDDDNYADKADDIQRAKEGLSESE
                     YKEIYTKIQKKEIGMLEANYNNKQQKDKLAALEKSKQAIERQQKTSKIKNALSIGSSA
                     CSLINTAISGVNNCLNVKSSFESKIEVVKEAIKDKENNIKKLDELNTQMVEFKDKTLK
                     ESVIPFVEKFDSTVKNQDIFENEISKLKMKEVLTELSTKFGSLKMENSEEISIIFKKV
                     QDMMETQIIITDKIDKKKDNLAMGELIYQMSDSGNQMNEYQKKLIHQIELNQVRYLCQ
                     VEAAAFQLWTFPFGSNIVNILNRCHVGITEDENEVINQAKEQNRQIREFLDQDAYQWQ
                     KTDNHILKVALTGSLDGKSRVGFENTYSLYDCNEEEVKKLLTGDEISFEVPLNKNFDA
                     IKYVTMYANIPNLRRNILEDSLKVKVHIHLYDSGYFSLYDDKKDVYYQYVFPQNYINI
                     THGLDIKYNDSDSINSIWSSVEDKGIEKFKNAGLNSGRSPYSMAKISLKAHFNRKLSY
                     DSLTNEQKKKLESYFDKPSKYAWSDSIDILRSLGYIDLKGILSKSWYEIKKDIDSDGE
                     IMKHFSILQVNLLERIIYEQTSILKENIPNLTIELVGCGIYVESEFNYLKQNDLKCYE
                     ERLVENTIIG"
     gene            complement(12113..14608)
                     /locus_tag="PC465_003265"
     CDS             complement(12113..14608)
                     /locus_tag="PC465_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2650545.1"
                     /translation="MPENNNQLLEEITLLLNEGKVAINKAENQNLILILGGTGCGKST
                     AINYLAGCVMMEVEDEDTGISYIDCLDPVAEIGSGAVSQTLYPNIVNMRKPIEGMDAK
                     LCDTAGFSDNRGVAHDISAAVSLGEVFKNSASICAVIVLIPEADILDSRLTKVLDLFQ
                     QLNMCLHKENFKGSITFFISKSFLERTEKQIYNVIKRKYEQLCENLDSNIEEKAWLFE
                     ELLKDNGKNIHLCKPLASDEREGLLKQVLELDEVKDKTSAFQYPISADARLVLDTLIK
                     EIQNNIVSSLEDYVKAYTEDFINIIGSITMIQEIAKYDEVVKVFKNWLESTTSLTIES
                     FINVLAKQSGLFLQDSCMKLQNKIKGNLDIIDALSKYTEHGTGEILLPSVHMEFIIEK
                     ASKKIMEQNFIIIRKNLEKVLVSYEVQKQVFTLPNREKLMEVANKKDYVYSVSDFNSI
                     LTNVTVTQNEELEDSITRLSAYGEEGNEIIREFIGKYILNPFIVKTININDKKGIEIR
                     ALIPNLVISSVLEYFKNRKVDDNVSTFMFFAKDTIYMDDNLGMNFASEKNIILASNNL
                     DVGSNVKINVSGKSGELVDNSMYGKNGEDGRDAGNIYLYIKEEIRNYRLTLIANGGNG
                     SKGIDGKNGETGASGSNGADAGYTSYFHGQMFKGYFEKGTSGKKGEKGGAGGNAGRGG
                     NAGKKGNIYFISDSEEQKNRIINHCDITVKDGEAGPNGRPGLGGYGGSGGYHGYNTLS
                     FSPSGIDKTVYYTGYFTSWDYKLDSIIKYHIEFSGGSWNEGKTGPAREYAEYGDRGDN
                     GGFNAPNTKLSTAVSKVEENLIKEKYQGYCSEI"
BASE COUNT         4911 a         2697 c         1675 g         5715 t
ORIGIN      
        1 taatatatat tttaaatttt cttttttaat aaatcttttt cttttaataa atctatttaa
       61 ttttcttctt ctatatcaga gccaaaggga atccatgcat taccaaactc tttatcttta
      121 aataaataag ctaatccagt tatttgcttc aatctaagaa tttcatcaac ttccataccc
      181 aggtgctttg atatccattc atcagatttt ccaatttcac aaagttcagt tataatttta
      241 ctcattaaat ccacattatg agaacctctt gcacgattgt gtcgaatagt acttgccatt
      301 ctttcatcaa gagatttatc aattactgaa acaggaagaa gtccattttc tctatcatat
      361 atatcctcat tttcaagcat tactctatat ctatgaaaac catctacaat aatatactta
      421 tccttttcct cattataata acagacaatt ggcattgtat acccatcttc ttttatactt
      481 ttatacaaca actgcatttc tggtggggct actgcatttg gattatagtc gttagattct
      541 atcttttcga ttggcactgc gatgattcca tatacaggac ttttatattc catagcatct
      601 taactcctat ctaatgaatt ttttcatatt tcttcttaat atattccgtt ctaattctct
      661 gttcttttgt aggaccaaat cccataaatc tacacatatg gtcatttttt aaaatacaat
      721 aacacattct tttccaactt ggtatatctt tggtaaattt aatatcatcc gtatcatcag
      781 gtatatcatc caaaaatatg actctactct ttttatcttt tgtatgattt gaaactccat
      841 ttaattctat tttataacct tttctcaaca attcacgtat aactatttct gacaaaccac
      901 cacctgtatt ctgccaaaac tcaatagatg ttgaaaattt tttaatatag ctattcctta
      961 tattttcagg taaggtatca agcaaaaaat atgtgaaact tttccatgtg tgtccatatg
     1021 gcaatttaac actacgatat cccatagctt ttgttttgcc ataaatagaa gtaaaattaa
     1081 ctccttgtac tctagcaacc aatttcaccc atacatctgg gtccaatatt ctgtataaat
     1141 ttaaactctc ttttgctgaa tcattaaaag gtgatgccac tctcattttt cttggagcta
     1201 ctccagcttt atagaataag tcataaattt tattatagtc atagtcaaat ttatagtgtg
     1261 ctaaccatat atcttctatt tcccaatcat atataggaga tgccgtccag acatttttaa
     1321 attccttagt tatccagcac tttcctttat atccatgctg tttattcaca atagaacaat
     1381 aacgttgtag agattctgct gctcgtgttc ctaataagca aacaactttt gcaccttcat
     1441 gtatatctct aatccatcta ccaaattgtt ttgccaaact ttcttgtctc attttatatt
     1501 tataataagt aaaaggatta tttttttgat ttattatgta ttctttgact ggcatttccc
     1561 ttacccataa ctcttctttc tcatcatccc atggatacca atacatttca taatttccta
     1621 cagcagttct tgtagccatt ggtaaacaca cccaatatgg ttcaatatct tcaatattat
     1681 cttcaaatac tttttcaaca tattcagtag tcaaactata ttgagcctca aaatcttgat
     1741 gaaatactcc tattttggaa cttatattat tctttctctt ataatccaaa actaaattta
     1801 gcagtaaacc actatctttt cctccgctaa aagatacata gatataatca aattcattaa
     1861 aaagataaga aagtctttct tgaaaagctt caaatacatc ggattctaaa tatctcttat
     1921 ccatttgaat tatccccttt caattagaag tttataaaac cttacaatgc aatattatta
     1981 tgctttttta gcagtaatca gcataaatta tacattattt aaatacacaa atccaactaa
     2041 ctacatataa ttataatgta attatacttt tgtattataa actatatttt atcattattt
     2101 tacatttttt tccaatatat ataaatatca tatttttcta ttagctaaaa ctaattactt
     2161 tatatttcta cgtattagta taataataca taaaaacttg aataatgcat aaaaacttga
     2221 catactgttg tcataattac tttgctataa ttaaaagtaa aaatggaggt aaattctaat
     2281 gtatgaacgt atgcttgata aaagcaataa accctgtttg tctcaaataa tagaatatat
     2341 aggtaaagat ggatatgcac gattgtgtaa gttggaaact tacttgaaaa ctcaatataa
     2401 tttatcaaga gaacttcgat ttccttttgg aaacaattat ggttggggtt acaaatatag
     2461 ccataaatct tttcatttat tttatgcttt ttttgaaaaa ggtgcattta ctgttctgat
     2521 tcagataggt gacaagcaag ttccagcagt agaaaaaacg ttggtagctt tgacaccaaa
     2581 agctaaagag ctctgggtca ctcgttatcc ttgtggcaat aatggaggct ggattaagta
     2641 tcgtatttta gaagatgcag acttacttga tattattcaa tatataagag caaaaaaatc
     2701 tccacctaaa caaaattaac ttttattttt tgtgatttaa atatagtgta tataaattcc
     2761 attcttttca tataaaaaaa ataatataaa aaatatctat tagtataact tatttagtat
     2821 gtcttattct actttttaca gataattaaa aagttttatc ataaataaat cataactaga
     2881 catcctagta aatcaaaatt aatttattct tttttattag aatttttgat aacagtccct
     2941 atacatatgc caattatcat tccaaaaatt agaccataac acattgtgat acctacattt
     3001 cctttagaaa tacctatagc acaacctata gccattccaa gtatcatgcc tataaacata
     3061 catataataa ctaaattgtt gtttttattc atagttttct ccattcaata tattttaaat
     3121 tgcctagctc gccttcttag cttaaaacaa agaaatataa attaactttc tttcattcta
     3181 atatctgctt gtataaatgt caaacaacac atttcttgtc ataacctcct ctttttgaag
     3241 taagtacaat ctcccagacg caataatatc aatttcctaa aaccatttaa gtaactttta
     3301 tatttacata atatttacaa tcataaacta tattgttatt catttataca tcataaacac
     3361 tccctcctaa tcattattat acttaaaata atgttcattt ataataatat atctaacgca
     3421 ctttaattga aaaaactaaa actttgcctt tcattcccat atataaataa gtatactttt
     3481 tgatgctcta ttacaaatca accaaattaa ttgatataaa ttatcatttt ctgttgaaaa
     3541 taccattcgc acatgctata cttaattgca taaatggtaa taaatgtcat atgattttac
     3601 aaatctatta ataacaatta ttacttttac tgtattttaa attttttgga ctaaatatca
     3661 agaactttct aaaatacaaa gtacaaaaaa tttatataag ttataaattt atatgaacta
     3721 gataagctca aacaatatgt tatgtataaa ctgtgtagta ttcggttata aatttatata
     3781 aattatataa gctagataaa gtattacctc aactatataa gctagatata taaattgctt
     3841 atataagcta gataagaatt atttcaacta tataaactac atatataaat tacatacata
     3901 agctagatat ataaactaga tatataaact gcatatataa gctatataag aattatttca
     3961 accatataaa ctacatatgt aaaattcatg taaatttact aatataaatc aaataaaatt
     4021 actaaactct ctaaactaat tttgtaaaac atactctatt tttaacattt gttaccttat
     4081 acataagtac aaacaaaatc taactaaatg aaaggataat gtaaaatgaa tattttaaaa
     4141 atgaaaaaaa cagggatatt tttaggagga gtactttttg gtactgtagg tgttaagata
     4201 ctttcaagtg attgtgttaa aaaaacttgc actcgtgcaa cagcaggagc attgaaagtt
     4261 aaagattctg ttcttgaaac aactacgaaa attcaagaaa atgtagaaga tattttagct
     4321 gaagcaaaag aaatcaacga gcaagaagac ttatctacat ctaaggtaaa cgttgtacaa
     4381 gatactctta aatgcgaaca agaagttctt aaaactgaaa ctataaaaac tgtagaagat
     4441 actaattcta atagcattaa atgtgaagaa atcaaagata acgtaattga agaaaaaaat
     4501 agtacttgta caacagaata aatttaatga ttattatgat taataatatc aggaggaagt
     4561 aaattgaatt tttatataaa acacgaaata agaggtcgta tacgctttga cttacaactt
     4621 ggcaaattaa acaacaagca gtccgatact ctcttatatt atttaacttc tataaatggt
     4681 attaccaaag caaaagttta cgatagaact ggtgatgcag tcatttatta cactggtgaa
     4741 agagaataca taataagaga aatcactaaa ttcagtttta acaatagcaa aatagaaaac
     4801 ctagttcctg aacataccag cagggaatta aacaattatt atagagacaa attagcaaat
     4861 aaactgctag tcaaaagtat ctccaaaata ttttttccaa agtccttaag atttttttta
     4921 attggacttc attctataaa atattttaaa aaaggtctct cttccctgct aaataaaaaa
     4981 atagaagttt ctgttttaga tgccactgct ataggtattt ctatttttag aaaagatatc
     5041 aatacggctg gttcagttat gtttcttctt ggtatcggtg aactattaga agaatggact
     5101 agaaaaaaat ctatagacga cttggctcaa agtatgtcac taaacattga aaaagtatgg
     5161 ttaagaaaag gtgacactga aatcttaatt ccaatttcag agataaagga aggagattta
     5221 gtaagtgtaa ctatgggaaa tatgattcca ttggatggag ttatagtatc aggagaaaca
     5281 atggtcaatc aggcatcact tacaggtgaa tcccttgcag ttaacaaaaa agaaggctct
     5341 tacatatatg ctggaactgt aatagagcaa ggcaatattg ttatgtgcgt caaggaaaaa
     5401 gctggtacta ctagattcca gaaaatagta actatgattg aggaatctga aaaactaaaa
     5461 tcttctgtag agagtaaatt tgaacatcta gcagatacat tagttccata cagcttttta
     5521 ggaagtatat taacctatgc aattactaga aaccctataa aatcactctc tatattaatg
     5581 gtagatttct cttgtgcatt aaaactctct atccctattt cagtactatc agccatgaga
     5641 gaatgtaaca ataacaacat tactgtaaaa ggtggaaaat ttcttgaagg tgttgcatgt
     5701 gcagatacta ttgtatttga taagacaggc acattaacaa aagctcaacc aactgtttca
     5761 gatataatta cattccaaaa ttataataag gaggatatgt taagacttgc agcttgctta
     5821 gaagaacact tcccacactc catagcaaat gcagtagttt atgaagctga aaaacaaggg
     5881 cttagtcaca aagaaatgca tacagaagta gaatatatta ttgctcatgg catttcaaca
     5941 aaagttgatg ataaaaaggt tgtaataggt agcaaacatt ttgtatttga agatgagaag
     6001 tgtactatcc cagacggtga ggaggataag tacaataatc tatcagatga gtattcacac
     6061 ctatttatgg caatatcagg taaattatca gcagttattt gcataaatga ccctttacga
     6121 aaagaagcaa aatatgtaat ttcaaattta agagaatgcg gaataaaaaa gattgtgatg
     6181 atgactggag atagcgaaaa aacagctaaa tctatagcaa gtaaagttgg tgttgatgaa
     6241 tattattcag aagtcttacc agaagacaaa gccaattttg ttaaaagtga aaaactcaaa
     6301 ggtcgcaaag taattatgat tggtgatgga atcaatgatt ctcctgctat ttcagaatca
     6361 gatgtcggaa ttgcaatgag tgaaggtgct gaaatagcaa gagagatttc agatattacc
     6421 atatcagcag ataatttgaa taatttaatc gttttaaagc agattagtaa taagcttatg
     6481 aaaagagttg atttaagttc taagtttatt atcggcttta atttaggttt gattttactt
     6541 ggtgtaggtg gatttgttag accaagtaca tctgcctttt tacacaacgc atctactgtc
     6601 ggaataagtt taaacagtat gacaaattta ttggaaaaca ccaatactta taactaccat
     6661 taatctccat tacataaaac atatgatata aaaaatttat aattcatctt ttaaaaagaa
     6721 tatgtcttaa aattagcttt tttctaatca aaattatata aagcatactt tacaaatttt
     6781 aaactcaact tatttctatt ttttacaaaa aaggagatga ttcaaatttt cattttgaaa
     6841 catccccttt tgtaaatttc tttaaaattt atatattaat tatattttca accaataatt
     6901 gtattttcaa ccaatctttc ttcatagcat tttaaatcat tttgctttag ataattaaat
     6961 tcagactcta cataaatacc acagcctacc aattcaattg tcaaattagg tatattttcc
     7021 tttagtatac tagtctgctc ataaataatt ctttccaata aattaacttg taatatagaa
     7081 aaatgcttca taatctcccc atcactatct atatctttct tgatttcata ccaactcttt
     7141 gacaaaattc ccttcaaatc aatataccct agactcctca atatatctat actatcgctc
     7201 catgcatact tactaggttt atcaaagtat gattctagtt tcttcttctg ctcatttgta
     7261 agtgaatcat aagaaagctt cctattaaaa tgtgccttca aagaaatctt agccatagaa
     7321 tatggacttc taccagagtt taatcctgca tttttgaact tttcaattcc tttatcttct
     7381 actgaagacc atattgagtt tattgaatct gaatcattgt atttaatatc aagaccatgt
     7441 gtaatattta tatagttttg tggaaataca tattgataat agacatcttt tttatcatca
     7501 tatagagaga agtatccact atcatataaa tgaatatgca cctttacttt taaactatcc
     7561 tctaaaatat ttcgtctaag gttcgggata tttgcataca tggttacata ttttatggca
     7621 tcaaagtttt tatttaatgg aacttcaaaa ctaatttcat ctcctgtcaa aagctttttc
     7681 acttcttctt cattacaatc atatagagaa tatgtatttt caaatcccac acgtgatttc
     7741 ccatctaaac tgcctgttaa tgctaccttc aaaatatggt tatctgtttt ttgccattgg
     7801 taagcatctt ggtcaagaaa ctctctaatc tgtctatttt gctctttcgc ctgatttata
     7861 acctcgtttt catcttctgt aatccctaca tggcatctat ttaagatatt tactatattg
     7921 cttccaaatg ggaatgtcca tagttgaaaa gctgctgcct caacctgaca caaatatcta
     7981 acctgattta attcaatttg atggataagt tttttctgat attcattcat ctgattacca
     8041 ctatctgaca tttgataaat caattctccc attgcaagat tatctttttt cttatcaatc
     8101 ttatcagtaa tgataatttg agtttccatc atatcctgta cttttttaaa tattatagaa
     8161 atctcctctg aattttccat ttttaagctt ccaaactttg tgcttaattc agttaaaact
     8221 tccttcatct ttaatttact tatctcattt tcaaaaatat cttgattttt aactgtacta
     8281 tcgaattttt ctacaaatgg tataacagat tctttcaaag ttttatcttt aaattccacc
     8341 atttgagtat tcaattcatc taatttctta atattatttt ctttatcttt aattgcctct
     8401 ttaactacct ctattttact ctcaaaacta gattttacat taagacaatt attaacacca
     8461 ctaatcgcag tatttataag agaacaagca gaacttccaa tactcaatgc atttttaatt
     8521 ttagatgtct tttgctgtct ttcaatagct tgtttacttt tctctagtgc agctaactta
     8581 tctttttgct gtttattatt gtaatttgcc tccaacatac ctatttcttt tttctggatt
     8641 tttgtgtaaa tttccttata ctcgctttca cttaacccct cttttgctct ttgaatatcg
     8701 tcagctttgt ctgcatagtt atcatcatct atagacttaa ctataatctc cttaatttgg
     8761 tcaaatttag ttcttctttc ttcatcaaca cctgccaaat tataagtcat tttatctaaa
     8821 gcattttttc tatcttcact tagctgttct ccaagtacaa atctcatacc atcagaatcc
     8881 aatttaaaat ctgaaaaatc aaccatcctg ttagtccatt tgtattcctc ttctttagct
     8941 gaaagatttt ccttcaaaga ttttgcactg tcaaatgccc ctagacaagc ttgaccaaca
     9001 ccactaaatg cagtcagtaa actcaatgcg ctttgtattc cagaaagaat taactgtgtt
     9061 ttcatttgtt cctcaagttt tgcctgtttc ttttttagtt cctctatgtc ttcttgttca
     9121 tcttctttca tctttataat ttcttgaatc aacaggttca tttttgcatt aacagaaagc
     9181 attttattct caagttcatt ttttaaaacc tctatttgtt gatttccaga ttcaatttga
     9241 gttaggatac tttccttata tgtattgaaa tatccttctt ttaactcatc tttctttcct
     9301 tgttccaatt ctcttaaggt cttatccaga taatctgtca aagaacgaat atctgtaaca
     9361 cgatttcctc caatttcact ttcttcaatc atctgcacat aaaatgctgt cttctgctca
     9421 agtgcaaata aaatcatact ccattcgcta aaattctgat tttttcctac aaaagattct
     9481 attctatcag actgcatcaa tttatttata aggtattcat agatttcctt tgcctcttta
     9541 taaaattctt tctttgtatt catatcatcc agagaaagta ctgctttatt tttcttctca
     9601 aaactatagt acttctgaag tatttctcta tttaattgca tctctatttt ctcaactgca
     9661 taaaaaattt cataaatatg tgaaaattct aaaatatcag cttctaaaat tcctactgca
     9721 cacaacagtc taagatttct ataaccttta attccagaaa aaccaaatct ctcgaaaaat
     9781 tcatagaaga atgtatctat tgacaaagaa tactcctgct ttaacaattc cttttctttt
     9841 agtgcatctc cagagtgacc gtcttttccc tctgctccgg ctgaacctga atcttcacgt
     9901 ttgctaattg tccagtcctt atgttcttca taaagagtat ttaatttctc tccatcatct
     9961 actgcttgct tctgatttaa agcatgatta aacacatatc tatcaaaata atagtagttt
    10021 ctatcactat catccattgg aggagaggta cctatatatc ttattgtttc ttcatatata
    10081 cctctaattc caccaagacc tcctgcacca ccagctcctc cagagcctcc ttttcctgct
    10141 aaaccatgat ttccatcttt tttacttata gcacttttta ataaaggagc ttttccaagg
    10201 agataaacct gtccagactt gcttccaaga cctgcatttc caccattacc tcctgtgcct
    10261 ccagttccac cttgttttcc tttttctgct tttaccacat agtattttgt acctttaaca
    10321 ttagcaaatt cttttgactc ttttttagaa cctattttag catttgcccc agcttctcca
    10381 gttatccctg tatctccttt ttttccatct tgtccatttc caccacgtcc accatctacg
    10441 taaagtttaa gttctcctct tttttctatt tctttaaaag ataatatgat atcacctgaa
    10501 gtacctgcat tatttccatt tcttccattc attccgtcgt aaatagaact ttctccaacc
    10561 aatttttctg catccttacc agatacgttg attgaataag tcccttctgg tatatgtaat
    10621 ttttctgtaa gtagtacaat attcttacct gagaagactt ctttctccat attacagtca
    10681 attttcaact cacaatctcc atacatatat atagatgaca aaatattaag ttgataacca
    10741 gatattattt tagtcaaatc cgataaattc actttaggta taggaatata tatagaaagt
    10801 acattttctt tctcatatga ttttatatat gtacaacttt gaatcttctc tatcctatac
    10861 tctgcatctt caagcctttt ggcttcttct tccctatatt cttcttctgc tatccaatat
    10921 ttgatatctt tcaatgtatc ttctaaagta ttttttagca atgattttaa caactcactt
    10981 agaccaacaa tatgagtctc actacagtaa ctatttaact ctaaaagaag acgtgtttct
    11041 tctaatatat tcactttctg tacgccatca ccatatgaaa gttcttgtac aaactccata
    11101 agctctttca tattattagt cctactacat aaatctgtat acatcttatc taattgaatc
    11161 tttttatctt ttagactatt tatagaagat agaatggaaa tagaatcttc catacctttt
    11221 ttaacacttt ctatataagg aactaaaagt ttttctaggt ctttataggt tacatcaaca
    11281 gctttttgta tttctatttt acaagaagca gtaagcatca atcccaaatc tgttttttca
    11341 aatgtttcag gtagattttt catttcattc aacaactttt ctggctgttt atctagtgga
    11401 ttacataatt taatagatac accatctgat aatgctacat ttaataagta cactaattcc
    11461 ttacaaccgt cgtaatcttt ctcttgacta tctaggtctt cttttgcttt ttccaatata
    11521 tttcttattt tttcttctgt tacattacca attagtgttt taggtatttt attgataaga
    11581 aagaagaaat tttctttata ctttgcataa tcaccaagca tatctttcaa atttttgcct
    11641 gtttctatca ataatgtatg tctagagtcc agtagggatt gatagtctaa aataactacc
    11701 atccctttta cctttgaaga tgtggaaata gtttccctta caagcatagc accagcaatc
    11761 atatactctg ctccacggtt gtcaaaaaaa cctgggcaat cacataatga aaaatctcta
    11821 tttgcaatat ctacaacttc tggacataaa gtcttagaat atacaccatt tccaatttcg
    11881 acagctgaat cttttgcagt tatatatatt tgtccagtct cttcatccgt tttttcttcc
    11941 atcacacagc cttttaaata atttatacaa gtactctttc caacgcctga agcacctagg
    12001 aataacaaaa ttgacttttc ttttaagtca tattttctaa gctcgtctct tccttcttcc
    12061 aaaaggttta cgatttcact ataaagttta tttgccatac atccatccct ttctatattt
    12121 cggaacaata gccttgatat ttttctttaa taagattctc ttctaccttt gaaacagctg
    12181 ttgataactt agtatttgga gcattaaatc ctccattgtc tcctctatct ccatattcag
    12241 cgtattctct tgctggtcct gttttacctt cattccagct tccaccacta aattctatat
    12301 gatatttaat tatactatct aacttataat cccaacttgt aaaatatcct gtatagtata
    12361 cagtcttatc tataccactt ggagaaaatg aaagtgtatt atatccgtga tagccaccac
    12421 ttcctccata tccacctaaa cctggtctac catttggacc tgcttctcca tctttcactg
    12481 ttatatcaca atgattaatt attctatttt tttgttcctc tgaatctgaa atgaagtaaa
    12541 tattaccttt cttaccagca tttccacctc ttccagcatt tccaccagct ccaccttttt
    12601 cacctttttt gccacttgta cctttttcaa aatacccttt aaacatctgt ccgtggaaat
    12661 aacttgtata tcctgcatca gctccattac ttccagaagc tcctgtttca ccatttttcc
    12721 catctattcc tttagaacca tttcctccat ttgcaatcag tgttagacga taatttctaa
    12781 tttcttcttt aatatataag taaatattac ctgcatctct accatcttca ccatttttcc
    12841 catacataga attatctaca agttctccgc tctttccact tacattaatt tttacattac
    12901 tacctacatc aagattgtta gaagcaagaa taatattttt ctctgatgca aagttcattc
    12961 caaggttatc atccatataa atagtatctt tagcaaagaa cataaatgta gaaacattgt
    13021 catctacttt tctatttttg aaatattcca atacactgct aattactaag tttggaatta
    13081 atgctcttat ttcaatacct ttcttatcat taatattaat tgtttttact ataaatggat
    13141 ttaaaatgta tttaccaata aattctctaa ttatctcatt accttcttct ccatatgcac
    13201 ttaatcttgt tatactgtct tctaactctt cattttgtgt aactgtaaca tttgtcaaaa
    13261 ttgaattaaa atcacttaca ctatatacat aatccttttt atttgcaact tccattaatt
    13321 tttctctatt tggtaatgta aatacctgtt tttgcacttc ataagaaact aaaacttttt
    13381 ctaaattctt tcttattata atgaagtttt gttccattat cttcttactt gccttttcta
    13441 taataaattc catatgtaca gaaggtaata aaatttcccc agttccatgt tctgtatatt
    13501 tacttaaagc atcaattata tctaagtttc cttttatctt attttgtaat ttcatgcaac
    13561 tatcttgtaa gaataagcca ctttgtttgg ctaatacgtt gataaaactc tctatagtaa
    13621 gacttgttgt actttccaac cagtttttaa atacttttac aacctcatca tattttgcta
    13681 tttcttgaat cattgttata cttccaataa tattgataaa atcttctgta tacgccttaa
    13741 cataatcttc taggctagat acgatattgt tttgaatttc ttttatcaac gtatctaaaa
    13801 ctaatcttgc atctgcacta attggatatt ggaatgctga tgtcttatct ttaacttcat
    13861 ctaattctag tacttgcttt aataagcctt ccctctcatc tgatgcaagt ggcttacaaa
    13921 gatgaatatt ttttccatta tcttttagca attcttcaaa taaccaagct ttttcctcta
    13981 tattactgtc taaattttcg cataattgtt catattttct ttttataaca ttatatattt
    14041 gtttttctgt tctttctaag aaactttttg aaatgaaaaa agttatacta cccttaaaat
    14101 tttctttatg aagacacata tttaactgtt ggaacaggtc tagtactttt gtaagtctag
    14161 aatctaatat atctgcttct ggtatcaata caattactgc acatatagat gcagaatttt
    14221 taaatacttc acctaatgaa actgctgcac taatatcatg ggctactccc ctattgtcgc
    14281 taaaacctgc agtatcacat aattttgcat ccattccttc tattggtttt ctcatattta
    14341 caatgttcgg gtataaagtt tgagaaacag ctcctgaacc aatctctgcc acagggtcta
    14401 agcaatcaat atatgatata ccagtatctt catcttctac ttccatcatt acacatcctg
    14461 caagatagtt aattgcagta cttttgccac atcctgtccc accaagaatt agaattaaat
    14521 tttgattttc agccttattt attgctactt ttccttcatt taataagagt gttatttctt
    14581 ctaaaagttg attgttattt tctggcattt attttccccc ttggttatat attttattta
    14641 aataaagttt aatcccttaa gtagattaca aagtttttag actatattta aatttgtttt
    14701 ttatttttta tttttaataa atttgctttt tcactaaatt tgcattttca ctcaataatt
    14761 attcttcttt gtttattaaa ataactgtgt tgtataatat aatctttacc aacacagtta
    14821 ttctatttaa tgcgcttatt ttattgtatt ttatgtaata cagttgtttt ttatattata
    14881 cgtccattat tttcctatgg ttattacata tagattttta attatatttg taccattaat
    14941 ttaaacattc ctatactact gcttaagttt tacacctata ccagcttgaa tattttat
//
LOCUS       DAMJXI010000086        14523 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.091, whole genome shotgun sequence.
ACCESSION   DAMJXI010000086 DAMJXI010000000
VERSION     DAMJXI010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14523
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.091"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            82..930
                     /locus_tag="PC465_003266"
     CDS             82..930
                     /locus_tag="PC465_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDF2650546.1"
                     /translation="MNNQKNLNIPITISSYTLGTEVSFRDRVRIAKEAGFDGIGLRAE
                     NYIDAKNAGVTDEEMIAILNEYDMKVTEVEYITQWGREEDRTEAQREKEQNVYHMAHL
                     FNVKHINCGLLEMIPEEQIITALGELCDRAGELIIGLEFMPYSGVPDLATAWRVVKGC
                     NRENAMLILDTWHWARAKQTAEDLAPVPADKIVSIQVCDVLETPYEKLRDESLHDRLA
                     PGEGYGNTEEFVKIIKEHNISPRVIGAEVISDSLISKGLSTAAETVFNATKKVLDKAW
                     SEVSPK"
     gene            1024..2946
                     /locus_tag="PC465_003267"
     CDS             1024..2946
                     /locus_tag="PC465_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2650547.1"
                     /translation="MKISSMFTPIRIGSMTVPNRFVVPPMGNNFANTDGTLSETSKAY
                     YLERALGGFGLITIESSVVDKKAKGGPRKPCLYDDSTIDSFKNVIDACHDAGSKVSIQ
                     LQHAGSEGNEKVAGHPLKAASAIPASNGRNTPLAITTEEIYELIESYGDAALRAQKAG
                     ADAVEVHCAHGYLVSSFISQRTNKRVDEFGGCFENRMRLPRLIIENIRKKVGNSLAIL
                     CRINSTDDVPGGIDVHDSSVIAAYLEDCGIDGLHVSRSIHIHDEYMWAPTTLHAGFSA
                     ELVTEIKKAVSIPVITVGRYTEPQFAELMVRQGRCDLVAFGRQSLADPEMPNKAKNGK
                     LDEMIPCIACLQGCVPNMFQGKPIACLANPILGHEAELKPAEISKEVLVVGGGVGGML
                     AAWVCAKRGHNVTLVEKSEVLGGQMRLAAYPPGKGDITNLVRSYISKCNQYGVKICTN
                     TEATVELIKEKSPDVVIIATGATPLVLPIPGINDSGLIHAVDLLDGKKSCGKKVLVVG
                     GGMVGCEVAAFLGEQEHEVTVIELREEVGADVISEHRKFLMNDFENYNIHTITGAKVS
                     KFYDDGVDYLLTDGTEHDLKGFDSVVLAMGSRNYDPLSEVIKEVVKETYIVGDAVKAR
                     RALDATKEAFEVALNI"
     gene            3028..3891
                     /gene="aroE"
                     /locus_tag="PC465_003268"
     CDS             3028..3891
                     /gene="aroE"
                     /locus_tag="PC465_003268"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDF2650548.1"
                     /translation="MEISGRTGLFALIGTPVGHSKSPVMYNYSFKKLDLDYRYLAFDI
                     TVDKVKEALLAIKTFNIKGANVTMPCKSAVTEYMDELSPAARIIGACNTIVNDNGKLV
                     GHITDGVGYVRNLKENGVEVKGKKITIMGAGGAATAIQVQCALDGAREISIFNPKDDF
                     YKRAEQTVENIKKDVPECVVNLYDLEDTNKLYEEIQSSDILTNATLIGMKPYDNETNI
                     KDTSVLRKDLVVTDVVYNPKKTKMIEDAEANGCKAIGGLGMLLYQGAEAFNLYTGLEM
                     PVEEVNELCFK"
     gene            4091..5308
                     /locus_tag="PC465_003269"
     CDS             4091..5308
                     /locus_tag="PC465_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2650549.1"
                     /translation="MNNKKYYPTAIALYFSYFLLGIGISILGQYKPEFSSMWGAKTLS
                     DGTLDVSIVLAVIAALGLGRLISYPFAGPISDKYGRKVSGLIGNFLHAIFFVGIVFSP
                     NFYIAYVFAIIGGAANSFLDTCVTPSCMEIFASLGTIANMFTKFTIALAQFLLPFIIG
                     FVAANSISFKVIFIVTAILIVIDAILIAVLPFPPANNVIDNKGKTVKSEKMKFTPTSI
                     ALVCIGFTCTSTFVLWLNCNQELGKLYGMADPTKIQSFYSMGVICAVLITSLLIKKYI
                     KPIRILVIYPIIALLMLLVVYFVQTPTICMLGGFVIGYSAAGGVLQLTTSTANEMFPT
                     NKGKITSIVMIASSIANYVILNIAGIITKSGGVNGPKYVVLFNVAITFVGILLALFVN
                     MRYEKEKVYDYDV"
     gene            5544..7409
                     /locus_tag="PC465_003270"
     CDS             5544..7409
                     /locus_tag="PC465_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HDF2650550.1"
                     /translation="MENVFKRLQEFNGYDGYKESFEMNYLCIYESIPLREQVELANNL
                     VDEILNMYKSESNEIYLLEDSNSKSLICYFEIFMKKINTLVKEMIIDEKWLYKLTKEL
                     IYKSKKVEYVKLGLVLSEKYLNVENLREVVDTFSKSGEYVFYLSNTIKKLEFYNTYLF
                     NLSKKATGSIKVFAIVNMENLDSKINSYLIEDGYKDTKYERLLMNYIISIVDLNEYLE
                     KRDLDKEKINNLARLICNYLLSVEFKYIGNKLELVNRFLPTVVNYGTNFESLYSIFLI
                     AINVLKDENIECNKIEFEKEINGILLSEKWKNIYFEALRDASGKTEDIIKMSEIYDVN
                     LSFDDLLPYLNRDIRDFEVYWYISKKGTTSSRLKLLNFFEETFKIDDLIGKMKDIEKD
                     KLTQEYYDDMLFFIVLKGSKSLYPEGKNISLKGIFGNINEVRKESINILKRYREKLSL
                     EELKIVKEAYEKEKNVILKDELRRVLYESNNLKKEFVNIEKIKVDEHGKDIYLTSIAV
                     AGSRFRNREYLEKELEKSKIYYLTREKDNLYDEKAIKIVGETGYVIGYVPRKENYILS
                     NLLDGGKLLYCRVTEYNLYEDCIYANVYLSYKDVIETVENSLKMVLDKSRIKLIN"
     gene            complement(7587..8951)
                     /locus_tag="PC465_003271"
     CDS             complement(7587..8951)
                     /locus_tag="PC465_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2650551.1"
                     /translation="MSQLLIKNAYLITMNADREVYETGSILIENNIIKNVGKFDINIV
                     DKDAEIYDAKGKILMPGLVNTHVHLSQQLGRGLADDVVLLTWLRERIWPYESSFNYED
                     SLISSTACCVELIKSGVTTFLESGGQYVDAMVEAVDKTGLRACLAKSVMDTGDGLPEA
                     WQKTTDEEINTQLDLFHKFNNTSNERIKIWFALRTIFNTTEELLVRTKELADKYNTGI
                     HMHIAEIADEISFVKQNNGVGTVEYLDKLGVLGPNLLAAHTVWLTHKEIDLFRLHDVK
                     VSHNPAAAMKVVLGFASIPEMLEKGIPVSIGTDGAPSNNRMDLMRDMYLTSLIHKGRT
                     LNPTVVPAEEVLEMATINGAKCALLEKEIGSLEVGKKADMIILNPDTIHCLPMHNPIG
                     NIVYSMTSENVDSTICDGKWLMKERKVLVVDESELLNKVKKQASKIKDKAEVKIPSKF
                     KIIK"
     gene            complement(9129..10472)
                     /locus_tag="PC465_003272"
     CDS             complement(9129..10472)
                     /locus_tag="PC465_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDF2650552.1"
                     /translation="MVPNTNNVQPGGNNSSLSFLDKMFKFSERGSSLKTEVIGGVTTF
                     LTMAYIVFVNPAILSEAGMDKAALITVTILATAIGTLIFAILGNAPFALAPGMGLNAF
                     FTYSLVIGAGIPWQTGLGVVFLSGCVFFTLAVTGLRKTIADAIPRELAVASSAGIGLF
                     LAFVGLKNMGVIIANPDTIVSLADFTPTVLIALFALILMAILEYKKVKGGILISIVVA
                     TIISVIFGFVELPTAIISTPPSIAPVAFKLDIVGALKFSLIGPIFSFMFIDMFDSLAF
                     LITCCKQMGLEDENGEIKDLGRMLYADVSSTLIGSFLGTSTVTTFGESASGIAAGART
                     GLASIVTAALFLATLIFTPLLGIVPTYAAAPALVMVGVFMFESIKQIDFADSKIAVPA
                     FVTVLLMPLTYSISIGLCFGFISYIIMHVVAKETDKISITLWIIGLLAVVNLVLS"
     regulatory      complement(10545..10646)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            10975..11628
                     /locus_tag="PC465_003273"
     CDS             10975..11628
                     /locus_tag="PC465_003273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDF2650553.1"
                     /translation="MTKIIKVQKPKFTGELEIIENLEDILEDIFNDEKIFNKIIENEV
                     ISDLDSVRVSFESCIFRNVSFENCNLKKIDLLDVVFENCNLSNSFFDGGSIYRVEFKN
                     SKLIGVRFDDCILKNVLFKDVLGKYSNFSFSKFKIVSILDSNFENSVFQEVKGDNLVF
                     EYTNLKKANFNGTKLSGIDFTTNNIEGIEIGIDDIRGAIFDVSQAIDLTKLMGIIIK"
     gene            11769..13040
                     /gene="brnQ"
                     /locus_tag="PC465_003274"
     CDS             11769..13040
                     /gene="brnQ"
                     /locus_tag="PC465_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDF2650554.1"
                     /translation="MRDIFIVGFALFSMFFGAGNLMFPPFLGMESGKDWLIPLIGFVV
                     ADAGIAMLVIIATARCKGSMDDVLRRAGKGLARVMSVAALACLALLVIPRTCATTYEM
                     GIMPIFGDHGPVAKAVFSIIFFGLTLAFTIRSSKVIDIIGKYLTPALLLVLFVLIVKG
                     IISPAGPMSPEHMIDKNLFGEGISQGYQTMDALGAASMATIMLMSIIAKGYTSDKDQI
                     GMTIKAGFVACVFLAVVYGGLTYLGATVSTLYDTSIPQASLLVEITSILLYGQVGKVI
                     LGVIVALACLTTSTGLTASISTYFEGISKASYKQLVIGICVASMLISNLGVDSIIAIS
                     VPILQTIYPVLLAIVVMELAGKHIKNDNAFKGAAYVTLVISLLSAINGMTGAVPFIQS
                     LPLAGLGFNWVIPAILGGIVGNFIKSNKQVA"
     gene            13242..14429
                     /locus_tag="PC465_003275"
     CDS             13242..14429
                     /locus_tag="PC465_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3798 domain-containing protein"
                     /protein_id="HDF2650555.1"
                     /translation="MLRKITAFMLSICLIIGLTGCSLLVGKKDKEKIIDDFKVAVVTQ
                     PLSENKVQYNMVEEMAKEYEEENKIDKDKDGQTKVKQTIKHVVLPENFTSNIDSAINK
                     IVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNL
                     GVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMIKETCKNIGLPFVQV
                     NTPNINTEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNEYMDEVILTKALELKYIVA
                     EQSNPSPIQTYPSVMGLKISEKDAQNYDKINDMISEKAKAFGMSNRLGGYPMPMDAFL
                     PSVAIYLATEMVKQDLTQEDVCDPDYLEAFTELRFGIGSEFTPLTEVLYNYQSVILSQ
                     LIY"
BASE COUNT         5372 a         1761 c         2523 g         4867 t
ORIGIN      
        1 atactactag taggataaat aaaaatataa aatcaaaaat actattaatt ataaagaaaa
       61 taaagggggc aaatttaagc tatgaataat caaaaaaatc ttaatattcc aattacaatt
      121 agttcttata cattgggaac agaagtttca ttccgtgata gagttcgtat tgcaaaagaa
      181 gctgggtttg atggtattgg attgcgtgct gaaaattata ttgatgcaaa aaatgcaggt
      241 gttacagatg aagaaatgat tgcaattctt aatgaatatg atatgaaagt tacagaagta
      301 gaatatataa ctcaatgggg aagagaagaa gatagaacgg aagctcaaag agaaaaagag
      361 caaaatgttt atcatatggc tcacttattt aatgttaaac atataaattg tggattatta
      421 gagatgatac cagaagaaca aattataact gcattgggag aattatgtga cagagcaggt
      481 gaacttatta taggtcttga gtttatgcca tatagtggtg taccagattt ggctactgca
      541 tggcgtgttg tgaaaggatg taatcgtgaa aatgcaatgc ttatattaga tacttggcac
      601 tgggctagag caaagcagac agcagaggac cttgcacctg ttccagcaga taagatagta
      661 tcaattcaag tgtgtgatgt tttagaaact ccttatgaaa aacttaggga tgaatcacta
      721 catgaccgtt tggctccagg tgaaggatat ggaaacacag aggaatttgt gaaaataata
      781 aaagaacaca atatatcacc aagagtcata ggggcagaag taatatctga ttctctaata
      841 tctaaagggt tatccactgc tgctgaaact gtatttaatg caactaaaaa agttttggat
      901 aaagcatggt ctgaagtatc tccaaaataa acttatataa tataaaaata tacagagtat
      961 tataatataa aacttttaaa tataaaactt ttaaatataa aacttgaaag gaaggaaaaa
     1021 cttatgaaga ttagttctat gtttacacct ataagaattg gttcaatgac agttccaaat
     1081 cgttttgtag ttccccctat gggaaacaat tttgcaaaca cagatggtac tttaagtgaa
     1141 acttctaagg cttattatct tgagcgtgct ttaggtggtt ttggattaat aactatagaa
     1201 tctagtgttg tagacaaaaa agcaaaagga ggtcctcgta agccttgttt atatgatgat
     1261 agcacaatag atagttttaa aaatgtaata gatgcttgtc atgatgcagg ttcgaaggta
     1321 tctatacaat tacaacatgc tggttctgaa ggaaatgaaa aagtagcagg acatccatta
     1381 aaagctgctt ctgcaatacc tgcatcaaat ggtcgtaata caccactagc aataacaaca
     1441 gaagaaatat atgaacttat agaatcttat ggagatgctg cattacgtgc acaaaaagct
     1501 ggtgcagatg ctgttgaagt tcactgcgct catggatatc tggttagtag ttttatatca
     1561 caaagaacaa ataagcgtgt agatgagttt ggtggatgtt ttgaaaatag aatgagatta
     1621 cctcgtctta tcattgaaaa tatacgtaaa aaagtaggaa attctctagc aatattatgt
     1681 cgtataaaca gcactgatga tgttccagga ggaattgatg tacacgatag ttcagtaata
     1741 gcagcatatc tagaagattg tggaatagat ggacttcatg tttcacgtag tatacatata
     1801 catgatgaat atatgtgggc tcctacgact ttacatgctg gattcagtgc agaattagtt
     1861 actgaaataa aaaaagctgt tagtatacca gtaataacag ttggacgtta tacagagcca
     1921 cagtttgctg agttaatggt cagacaagga agatgtgatt tagtagcatt cggtagacaa
     1981 agcttggctg acccagaaat gcctaataaa gctaaaaatg gaaaactaga cgaaatgata
     2041 ccatgtattg catgcttaca aggatgtgta ccaaatatgt tccagggcaa acctatagcc
     2101 tgtcttgcaa atcctatatt aggacatgaa gcagagctta agccagctga aattagcaaa
     2161 gaagttcttg ttgttggtgg aggtgttgga ggtatgcttg cagcatgggt atgtgctaaa
     2221 agaggacata atgtaacttt agttgaaaaa tctgaagttc ttggtgggca aatgcgttta
     2281 gctgcatatc ctccaggaaa aggagatatt actaacttag ttagaagtta tatttcaaaa
     2341 tgtaatcaat atggtgtaaa aatatgtact aatacagaag ctacagtaga acttataaaa
     2401 gagaaatcac ctgatgtagt tattatagct actggagcaa ctccacttgt acttcctata
     2461 ccaggaatca atgattcagg attaattcat gctgtagacc ttcttgatgg taaaaaatct
     2521 tgtgggaaaa aagtacttgt tgttggaggt ggaatggttg gatgtgaagt ggcagccttc
     2581 cttggagaac aagaacatga ggttactgtt attgagctta gagaagaagt tggtgcagat
     2641 gtaatttcag aacaccgtaa attccttatg aatgattttg aaaattataa tatacatacc
     2701 attactggtg caaaagtttc taaattttat gatgatggtg tcgactattt acttacagat
     2761 ggcacagagc atgatttaaa aggttttgat tcagtagtac ttgctatggg ttctcgtaat
     2821 tacgacccat taagtgaagt tataaaagaa gttgtaaaag aaacttatat tgttggtgat
     2881 gcagtaaaag ctcgtagggc attagatgca acaaaagaag cttttgaagt agcattaaat
     2941 atataaataa taaataaatt tttctttgta aataactgaa taggctattt gcaaagaaaa
     3001 tgataatatt gggaggagat tatagttatg gaaatttcag gtagaacagg attatttgca
     3061 ttaataggta caccggttgg tcactctaaa tcaccagtga tgtataatta tagttttaag
     3121 aaattagatt tagattatag atatttagcc tttgatatca cagtagataa ggtaaaagag
     3181 gcacttttag caataaaaac ttttaatata aaaggagcca atgttactat gccatgcaaa
     3241 tctgctgtta cagaatatat ggatgaactt tctccagcag ctcgtataat tggagcatgt
     3301 aatacaattg taaatgacaa tggaaagtta gttggtcata taacagatgg agtaggctat
     3361 gttcgtaatt taaaagaaaa tggggtagaa gttaaaggta aaaagattac aattatgggt
     3421 gctggtggtg cagcaactgc tatacaagta caatgtgctt tagatggagc aagagaaata
     3481 tctatcttta atcctaagga tgatttttat aaaagagcag agcaaacagt tgagaatata
     3541 aaaaaagatg taccagaatg tgttgttaat ctatatgatt tagaagatac aaacaaactt
     3601 tatgaggaga tacaatcaag tgatatattg acaaatgcaa ctcttattgg tatgaagccc
     3661 tatgacaatg aaacaaatat aaaagatact agtgttttaa gaaaagactt agtagtaaca
     3721 gatgtcgttt ataatcctaa gaaaacaaaa atgattgaag atgctgaagc taatggatgt
     3781 aaggctattg gtggattagg aatgttatta taccaaggag cagaggcttt taatctatat
     3841 actggattag aaatgcctgt agaagaagtt aatgaattat gctttaaata gataagagta
     3901 atatcttaaa caatgaaaaa acatacgtat ttcaatattt ttaataataa attacaaatt
     3961 gtcatagtgg gttttgcctc atagtccagt taaatttgaa gctttaactg actatacttt
     4021 aaatccatta tggggatgag tttattgtac acaaaaatgt taataaatta acaagaatgg
     4081 gagaaaaatt atgaacaata aaaaatatta tcctactgcc atagcgttgt atttttcata
     4141 ttttttactt ggtattggaa tttcaatttt aggacaatac aaaccagaat tttcatcaat
     4201 gtggggggct aaaacattat cagatggaac attggatgta agtattgttt tagctgttat
     4261 tgctgcacta ggattaggga gacttatatc ttatccattt gcaggaccta tttcagataa
     4321 gtatggaaga aaagtaagtg gtcttatagg aaactttcta catgcaattt tctttgttgg
     4381 aattgtattt tcaccaaatt tttatatagc atatgtattt gcaataattg gaggggcagc
     4441 aaattcattc ttagatacct gtgtaactcc ttcttgtatg gagatatttg ctagtttagg
     4501 aacaatagca aatatgttta ctaaatttac aatagcttta gcacaatttt tgcttccttt
     4561 tataattgga tttgttgcag caaattcaat atcatttaaa gttattttta tagtaacagc
     4621 gattcttatt gtaatagatg caattttgat agctgtgtta ccatttccac cagctaataa
     4681 tgttattgat aacaaaggca aaacagttaa atcagagaag atgaaattta caccaacaag
     4741 tatagctctt gtttgtattg gatttacatg tacatctaca tttgtattat ggttaaattg
     4801 taatcaggaa ttgggtaaat tgtatgggat ggctgaccct acaaaaattc aatcctttta
     4861 ctcaatggga gtaatatgtg cagtattaat aacttcttta cttattaaaa aatatattaa
     4921 accaataaga atattagtta tatatcctat aatagcttta cttatgctat tagttgtata
     4981 ttttgttcaa actccaacta tttgtatgtt agggggattt gtaataggtt attcagcagc
     5041 aggaggtgtt cttcagttaa caacgtcaac tgcaaatgaa atgtttccaa ctaataaagg
     5101 aaaaataaca tctatagtta tgattgcatc tagtatagca aactatgtta ttttaaatat
     5161 agcaggtatt attacaaaat cagggggagt taatggacca aaatatgttg tattgtttaa
     5221 tgtggcaata acatttgttg gaattttact tgcattgttt gtaaacatga gatatgaaaa
     5281 agaaaaagtg tatgattatg atgtctaata ttagtataat atacgcatag agaagtctaa
     5341 atctaggata gatttttatt aaaagtaatt aaaattaata aggatattat ttacagttat
     5401 aagatagggt atttacataa ttaataataa ggatattact agaatttcaa tttctagtaa
     5461 tatttttttg cgtataaatg taaacttgac gaaataagta gtataatcaa tataaattac
     5521 atcatgtaaa ggaggataat ttggtggaga atgtttttaa gcgattgcag gaatttaatg
     5581 gttatgatgg atacaaagaa tcatttgaaa tgaattacct atgtatatat gaaagtatac
     5641 cgttaagaga acaagtagag cttgcaaata atctagtaga tgaaatttta aatatgtata
     5701 aaagtgaatc taatgaaatt tatttattgg aggatagtaa ttctaagtct ttaatttgtt
     5761 atttcgaaat ttttatgaaa aagataaata ctttggtaaa agaaatgatt attgatgaga
     5821 aatggttata taaattaact aaagaattaa tatataagag taaaaaagtt gagtatgtaa
     5881 aactagggtt agttttaagt gagaaatatc taaatgtaga aaacttaaga gaagttgtag
     5941 atacattttc taaatctgga gaatacgtat tttatctgag taatactatt aaaaaacttg
     6001 aattttacaa tacatattta tttaatttat ctaaaaaggc tacaggttca ataaaagtat
     6061 ttgctattgt taatatggaa aatttagatt ctaaaataaa ttcctatcta attgaagatg
     6121 gttataagga tacaaagtac gaacgattat tgatgaacta tattatttca attgtagatt
     6181 tgaatgaata tcttgaaaaa cgagatttag ataaagaaaa gataaataat ttagcacgtc
     6241 ttatatgcaa ttacttgcta agtgtagaat ttaaatatat aggtaataaa ttagaattag
     6301 tgaatcgatt tttacctact gtagtaaatt atgggactaa ctttgaaagt ttatattcaa
     6361 ttttcctaat agctataaac gtcttaaaag atgaaaatat agagtgcaat aagattgaat
     6421 ttgaaaaaga aataaatggt atcttgctca gtgaaaaatg gaaaaatata tattttgaag
     6481 cattaagaga tgctagtgga aaaacagaag atattataaa aatgtcagaa atttatgatg
     6541 taaacttatc ttttgatgac ttgttgccat atctgaatag agatattaga gattttgagg
     6601 tatattggta tatatctaaa aagggaacaa caagttctag attaaaatta ttaaattttt
     6661 ttgaagagac gtttaaaata gatgatttaa ttggaaaaat gaaagatata gaaaaagata
     6721 aattgactca agaatattat gatgatatgt tattttttat tgtgcttaaa ggaagtaaat
     6781 cactatatcc tgaaggaaag aatatatctt taaaaggaat atttggaaat ataaatgaag
     6841 taagaaaaga atccataaat atcttaaaaa gatacagaga gaaactatct cttgaagaat
     6901 taaaaattgt taaagaagcg tatgaaaaag aaaaaaatgt tatattgaag gatgaattaa
     6961 gaagagtatt atatgaaagt aataatttaa aaaaagaatt tgtaaatatt gaaaaaataa
     7021 aagtagatga acatggtaag gatatctatt tgacttcaat agctgttgct ggttcaaggt
     7081 ttagaaatag agaatatctt gaaaaagaat tggagaaaag taagatatac tatttaacta
     7141 gagagaaaga taatctatat gatgaaaaag ctattaaaat agttggtgaa actggatatg
     7201 taataggcta tgtcccaaga aaagaaaact atattttgag caatttatta gatggaggaa
     7261 aactgctgta ttgtagagta actgaatata atttatatga agattgtatc tacgcaaatg
     7321 tgtacttgag ttataaagat gtaattgaaa cagttgaaaa ctctttaaag atggttttag
     7381 ataagagtag aataaaactt ataaactaag acgtttatat attgcttaga tgatgtaatc
     7441 ttaactgatt ggttattttt tctggaatta tggtgtattt tatgagcaat gctaatgaat
     7501 ataaaataaa aaaacaattg ttttgtatat atgatgtata taaatatatt tatatattca
     7561 tatttacaaa acaattgaaa tttatgttat tttataattt taaatttaga tggaatttta
     7621 acttctgctt tatcttttat tttagaagct tgttttttaa ctttatttaa taattcagat
     7681 tcatctacaa ctaatacttt tctttccttc attaaccatt taccatcaca aatagtagag
     7741 tctacatttt cactagtcat agaataaact atatttccaa ttggattatg cattggtaaa
     7801 caatgaattg tatctggatt tagaataatc atatcagctt tttttcctac ttcaagacta
     7861 ccaatttctt tttctagtaa agcacatttt gctccattta tagtagccat ttctaagact
     7921 tcttcagctg gtacgacagt tgggtttaaa gttcttcctt tatgtattag tgatgtaaga
     7981 tacatgtccc tcataaggtc cattctatta tttgaaggag ctccatcagt accaattgaa
     8041 acaggtattc ctttttctaa catttcagga attgatgcaa atcctagaac tactttcatg
     8101 gctgcagctg gattatgaga aacttttaca tcatgtaatc taaataaatc aatttcttta
     8161 tgagtaagcc aaactgtgtg agcagctaaa agatttggtc ctaatacacc tagtttatca
     8221 agatattcaa ctgttccaac tccattgttt tgctttacaa atgaaatttc atcagctatt
     8281 tcagcaatat gcatatgtat acctgtattg tatttatcag ctaattcttt agttctaaca
     8341 agtaattctt cagttgtatt aaaaatagtt cttaatgcaa accatatttt aatcctctca
     8401 ttagatgtgt tattaaactt atggaataag tctaattgag tgttgatttc ctcatcagta
     8461 gttttttgcc atgcttcagg aagaccatct cctgtatcca taactgattt agctaaacag
     8521 gctctaagtc cagttttatc aacagcttca accatagcat ctacatattg accaccagat
     8581 tctaaaaatg tagtgacccc agattttatc aattcaacac aacatgcagt agatgaaatc
     8641 aatgaatctt catagttgaa gctactttcg tatggccaga ttctctctct aagccaagtt
     8701 aaaagtacaa catcatctgc aagaccacgt cctaattgtt gggataagtg aacgtgtgta
     8761 ttgactaacc ctggcattag tatttttcct ttagcatcat atatctcagc gtctttatct
     8821 acaatattaa tatcaaactt accaacattt tttataatat tattttcaat aagtatactt
     8881 ccagtttcat atacctctct atctgcattc atagtaatta gatatgcatt ttttataagt
     8941 aattgtgaca taagtacaac ctcttttcta tatattttta tatctatgta ttatgataat
     9001 aaattttcta tacaaagtta atagcaaaat caatttatac ataaattgat tttgctattt
     9061 ataaatttaa aataaataag attttattct atataattta aaatattgac ctagaactat
     9121 ttaaaatatt aacttagaac taagtttaca actgcaagta aacctataat ccaaagtgta
     9181 atactgattt tatcagtttc tttagctacc acatgcatta ttatatatga aataaatcca
     9241 aagcataaac caatacttat actataagtt aaaggcatca ataaaactgt aacaaaagca
     9301 ggtacagcta ttttgctatc agcaaaatca atctgtttta tgctttcaaa catgaataca
     9361 ccaaccatta caagtgcagg agctgcagcg taagtaggaa ctataccaag taatggtgta
     9421 aatataagtg tagctaagaa taatgctgct gttactattg aagcaagtcc tgttcttgca
     9481 cctgctgcaa taccagaagc agattctcca aatgttgtaa cagtactagt tcctaagaat
     9541 gagcctatta aagtagaaga aacatctgca tataacattc ttcctaaatc ttttatttca
     9601 ccattctcat cttcaagacc catttgttta caacaagtaa taagaaatgc taatgaatca
     9661 aacatgtcta taaacatgaa agagaatata ggtccaatta atgagaattt caatgcacct
     9721 acaatatcta atttaaaagc aactggtgct atactaggag gtgttgagat tattgctgtt
     9781 ggcaactcca caaatccaaa tataacagat attattgttg caactactat acttatcaat
     9841 attccacctt taactttttt atattctagt attgccatta agataagagc aaaaagggct
     9901 attaaaactg ttggtgtaaa atctgcaagt gaaactatag tatctggatt agctattata
     9961 acacccatat tttttaaacc aacaaaagca aggaaaagac ctatacctgc tgaagatgct
    10021 actgccaatt ctctaggaat tgcgtctgca attgtctttc gaagacctgt tactgcgagt
    10081 gtaaagaaga cacatccaga tagaaaaact accccaagac ctgtttgcca tgggattcct
    10141 gcacctataa ccaaagagta tgtgaaaaat gcatttaatc ccataccagg agctagagca
    10201 aatggtgcat ttcctaaaat cgcaaatata agtgtaccaa tggctgtagc tagtatggta
    10261 actgttataa gggcggcttt atccattcca gcttcagata atattgctgg atttacgaaa
    10321 actatgtatg ccattgttaa gaatgtagta actccaccta ttacttctgt tttaaggcta
    10381 gagccacgtt cgctaaattt aaacattttg tctaaaaagc ttaatgatga attatttcca
    10441 cctggttgta cattgttagt gtttggtacc atttttacct ccaaaaaact ttaagatata
    10501 aacaaaaaaa tatatattca tatagataga atagaacata tattcagagt tgacattcta
    10561 ttcatagaaa acccatttaa ggtgagtttg tagaaactat tagaccgtat tactaatatt
    10621 atatgaacat tttctatttg tttttctgtt gtattatatc gtaatattgt attatttaca
    10681 ataaatataa taaaattatt cgtttttttg tcgattttat aaaaaattaa ggttatttat
    10741 tgaaaaaaat tactttttcc aataattgaa tatgtatgag tataatgtca attattctaa
    10801 cttgttttat actattaatg gaagtttatt ataaatgagt ttgtgatata attataaaag
    10861 tactgaatac atggatattt cgtaaaaact ttttaatata tcaaatatgt atattaagtt
    10921 aatatattaa aaaaaataat atcaaaaata atataattta tagtggaggg gaaaatgact
    10981 aaaattatta aagtgcaaaa acctaaattt acaggagaat tagaaattat tgaaaatctt
    11041 gaagatatac ttgaagatat atttaatgat gaaaaaatat ttaataaaat tatagaaaat
    11101 gaagttataa gtgatttaga ttctgtaaga gttagctttg aatcttgtat atttagaaat
    11161 gtgtcttttg aaaattgtaa tttaaaaaag attgatttac ttgatgtggt atttgaaaac
    11221 tgcaatttat caaattcatt ttttgatgga ggaagtatat acagagttga atttaaaaat
    11281 agtaaattga taggagttag atttgatgat tgtatactta aaaacgtttt gttcaaggat
    11341 gttttaggta agtattctaa cttttcattc tctaaattta agatagtttc tatcttagat
    11401 tcaaattttg aaaattctgt atttcaagaa gtaaaaggtg acaatctagt atttgagtat
    11461 acaaatttaa aaaaagcaaa ctttaatgga actaaacttt ctggcataga ttttactact
    11521 aataatattg agggaattga gattggtata gatgatatta gaggagcaat ttttgatgtg
    11581 tcacaagcaa ttgatttaac gaaattgatg ggaattatca taaaatgaaa aaaaaattca
    11641 taaaacaaat tgggaaaacg ttaacaatgt gtgaattttt accagattga catttttctg
    11701 aaaataaagt aagattatct taatattcaa aatattttca aagggggtaa tttagtgtga
    11761 gtaagcagat gagagatatt tttatagttg gttttgcttt attttctatg ttctttggtg
    11821 caggaaatct tatgtttcct ccatttttag ggatggaatc cggcaaagac tggttaattc
    11881 ctcttattgg atttgttgtt gcagatgctg gtatagcaat gcttgttatt atagcaacag
    11941 caagatgtaa gggaagcatg gatgatgtac ttaggagagc tggtaaaggg ttagcaagag
    12001 taatgagtgt agctgctcta gcatgtttag cacttcttgt aataccaaga acttgcgcaa
    12061 caacatatga aatgggtatt atgcctatat ttggagacca tggtccagta gctaaagctg
    12121 tattttcaat aatcttcttt gggttaactt tagcatttac tattaggtct tctaaggtta
    12181 tagacataat aggtaagtat ttaactccag cgttattatt agtattattt gttttaatag
    12241 taaagggtat aatttctcca gcaggaccta tgagtcctga gcatatgata gataaaaatc
    12301 tatttggtga aggtatatca caaggttatc aaacaatgga cgctctaggt gcagcatcta
    12361 tggcaactat aatgttgatg tctataatag ctaaaggata tacatcagat aaagaccaaa
    12421 taggaatgac tattaaagct ggttttgtag cctgtgtatt tctagcagta gtatatggtg
    12481 gtcttactta tttaggtgca acagtttcaa ctttatatga tactagtata cctcaagcat
    12541 ctttattagt tgaaataact agtatattgt tatatggtca agtaggaaag gtaattttag
    12601 gtgtaattgt ggcacttgcc tgtctgacta cttctacagg tttaacagca tcaatatcaa
    12661 cttattttga aggaataagt aaggcgagtt ataaacaact ggttataggt atatgtgtag
    12721 ctagtatgct tatatcaaat ttaggtgttg attctataat agccatatca gttccaatcc
    12781 tacaaactat atatcctgtt ttattagcaa tagttgttat ggagttggct ggtaaacata
    12841 taaagaatga taatgctttt aaaggtgcag catatgttac attagtgatt agtttattat
    12901 cagctataaa tggaatgaca ggagctgttc catttataca aagcttgcca cttgcaggtt
    12961 tgggctttaa ctgggtaata ccagctatat tgggtggaat agttggtaac tttataaaaa
    13021 gcaacaaaca agtagcataa taatttgtaa ttaatttaat tttataatat attaattttt
    13081 agtactatgg gtaggtttaa tctaaaccta atctacccat agtacttttt agattggatt
    13141 ataatagcat gtatataatt ttttataata taatttttct ttgaagtatg ataaaattag
    13201 taatagtgat aagaatgtac aaatttagga ggttttaatt aatgcttaga aaaataacag
    13261 catttatgct atccatatgt ttaattattg gacttacagg ttgtagttta cttgtaggca
    13321 agaaagataa agagaaaatt atagatgatt ttaaagttgc agtggtaact caaccattat
    13381 ctgaaaataa agtacaatac aatatggtgg aagagatggc aaaagaatat gaggaagaga
    13441 ataaaattga taaagacaaa gatggtcaaa ctaaagttaa acaaactata aagcatgttg
    13501 tattgccaga gaattttact tctaatatag acagtgctat taataagata gtaaagttgg
    13561 ctgacgataa agaagttcag gctattgtag tttcaactga ccaagcaggg cttttacctg
    13621 ctttacaaaa ggtaaaggaa aagcgtccag aaataataac tatttctgcc cctatgggag
    13681 atgataaaaa ccaattaagc caatttgttg atgtgaatct aggggttagt gcagaggaaa
    13741 gaggaaaagt attagctgaa cgttcaaaag aaatgggagc aaaagctttt attcattatg
    13801 cctctacaga tgatttgaaa gatgttaata tagccaaaag attagaaatg attaaagaga
    13861 cttgcaaaaa tataggattg ccatttgtac aagttaatac tccaaatata aatactgaag
    13921 aagacaaaaa caaagttaaa cagtttttaa atgaagatat tgaaaaacaa gttaaaaaat
    13981 atggaaaaga tataaatgta tttggtgtaa atgagtatat ggatgaagtt atattgacta
    14041 aggctttaga attaaagtat atagttgcag agcaaagcaa tccatcacca atacaaacat
    14101 atcctagtgt tatgggtcta aaaatatctg aaaaagatgc tcaaaattat gataaaataa
    14161 acgacatgat aagtgaaaag gctaaggctt ttggcatgtc aaatagactt ggtggatatc
    14221 ctatgccaat ggatgctttt ctaccatcag tagcaattta tcttgctact gaaatggtga
    14281 aacaagattt aacacaagaa gatgtatgtg acccagatta tttagaggcg tttacagaat
    14341 taagatttgg aatcggttca gaatttactc ctttaacaga ggtactttat aattatcaat
    14401 cagtaatttt aagccaatta atttattaat attaaggaag tgtctcaaaa tgaacttttt
    14461 agtttatgag gcactctttt tctattaaat caaatatatt tttatctttt taacaattaa
    14521 aaa
//
LOCUS       DAMJXI010000087        14147 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.092, whole genome shotgun sequence.
ACCESSION   DAMJXI010000087 DAMJXI010000000
VERSION     DAMJXI010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14147
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.092"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            430..1323
                     /locus_tag="PC465_003276"
     CDS             430..1323
                     /locus_tag="PC465_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HDF2650556.1"
                     /translation="MSNKIVSKRQLTDSIYLMEIEAPRVAKSSQPGQFIIIKNDEKGE
                     RIPLTIADYDREKGTVTIVFQTVGASTKKLAMFEENDFVMDFVGPLGQASEFIHEDIE
                     ELRNKKILFVAGGVGSAPVYPQVKWFKEHGLDVDVIIGARTKELIILEDDMKKVAKNV
                     YVSTDDGTYGFNGRVTDLLKDLVDNQGKKYDQAIVIGPMIMMKFMCQLTKELNIPTIV
                     SLNTIMIDGTGMCGGCRVSVGNETKFACVDGPEFDGHLVDFDQAMRRQSMYKTQEGRA
                     MLKLEEGDSHHHSNCGCGGNK"
     gene            1323..2717
                     /gene="gltA"
                     /locus_tag="PC465_003277"
     CDS             1323..2717
                     /gene="gltA"
                     /locus_tag="PC465_003277"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HDF2650557.1"
                     /translation="MDAKKVKVPVREQEPAVRATNFDEVCLGYNKEEAMAEANRCLAC
                     KKPKCVGGCPVGIDIPGFITKIKEDDIEGAAKVIAKSSSLPAVCGRVCPQESQCEGVC
                     ILGIKSDAVSIGKLERFVADWSKENDINLSDTEPKKNQKVAVIGSGPAGLACAGDLAK
                     KGYDVTIFEAMHEPGGVLTYGIPEFRLPKQAVVQPEIDNIRKLGVKIETNVIVGKTIT
                     VDELIEDEGFEAIFIGSGAGLPMFMNIPGENANGVFSANEFLTRVNLMKAYRDDYDTP
                     ISSGKKVAVVGGGNVAMDAARTALRLGSESYIVYRRSEKELPARAEEVHHAKEEGIIF
                     NTLTNPKEILVDENGYVKGMVCIRMELGEPDDSGRRRPIEIEGSEFVLDVDTVIMSLG
                     TSPNPLISSTTKSLDINKKRCLITDENGQTSKEGVFAGGDAVTGAATVISAMGAGKTA
                     AASIDEYLKAKVNA"
     gene            3083..5302
                     /locus_tag="PC465_003278"
     CDS             3083..5302
                     /locus_tag="PC465_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2650558.1"
                     /translation="MKKREKVFDGLVFKHILILLILLVLIDLTSTIIYASNSMEITSR
                     NMIEASKRELENYLEVNISLLKALSQDDRFSNGETSLIEKGKLLSPYQKEYNLFMIGI
                     TDTKGNASSTYRENVNSIKDKPSFEKAIKTKQVVVSDIEVSNVTGDKVFIIYVPIVKN
                     NEMIGTIFASFYFQDVNNLISRSNFDDSIKFLMIDKDYTIISHPNKKYVNDKSKMLDL
                     EGNIIGTTKSEILKNINKKCQGDFLSWDNWRLYNVKYTNIKWTNWTLVSKCNIFKNFK
                     NLIVNFMIKLYFYIVIFMILWKLSNAKLIEQLKKLAYYDSLSGIKNKEKFRKDSMYIL
                     KNYYQDNFYLVQLDVNKFKYINEMFGYAEGNKILIHISQVLNNNTNKYEICARMDNDH
                     FILLIACNTEDELLNRLSKINKEICNLNTTNSSKYKIVMSSGIYKITKKDDIKKIDLL
                     IDRANIAAKSKKEKYEHSYSFFNEDTRNRLYKEKRLEDNMNKALEKGEFIVYYQPKYS
                     LDDVNEIEGAEALIRWNSPEFGFISPIDFVPLFEKNGFIVNIDMFVFEEVCKTLNKWI
                     NKGYTPVPISVNMSRVHLYRDNFIENITDLISKYNISPEFIELELTESVVFDNLNILI
                     DIMKKIKEIGFLISMDDFGSGYSSLNLLKDLSFDILKLDRGFLIETTDTKRGKIIISK
                     IVEMAKAIDIKVICEGVETYEQVEFLKEIGCDKVQGYLFAKPMVLDEFEKHLNFKFD"
     gene            5449..6195
                     /locus_tag="PC465_003279"
     CDS             5449..6195
                     /locus_tag="PC465_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2650559.1"
                     /translation="MNILSIRNISKTYCGNIPFKALDKVSLNIEKGEFVSVMGPSGSG
                     KSTLLNIISTVDRQSEGEVVLDGYDVSKLKGEKLAEFRRKQLGFVFQDFNLIDTLTVG
                     ENIMLPLTLEGESIKDMNIQTKSISKFLGIDKILDRKTYEISGGQAQRCAIARAIINK
                     PAILLADEPTGNLDSKSTDDVLKLFTRINKEQKVTTLMVTHEAYSASYSDRVIFIKDG
                     CIYTEIKKSESSNSFYSDILAVLSQIGGVR"
     gene            6195..8075
                     /locus_tag="PC465_003280"
     CDS             6195..8075
                     /locus_tag="PC465_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2650560.1"
                     /translation="MDFRKFAYNNIVRNFRAYLAYFLSSVFSIMIFFVFAVSMFHPII
                     TKSGMQSGSTAFMALMTSELIIFGFSLLFILYSLGNFLKYRLKDFGVLMIIGMSNRQL
                     KKLILIENLIIGFLAVMLGILLGLSISKLFLLYLSKLFYMNLTEFYFPVKAMLLTIVS
                     FMILFLITGPMSLKLLSKKSILELLVGTKKPKKEIKSSKLFGIIGVICLILGYAMILF
                     GNKLKINGGMYTTALLITLGIFLFFSQFTILILKYLKNKEKFYKNKVNMLLISNLIYK
                     LKDNTRLLFLITILLSATLVAFTTTSTLVSSQGEASKNNFPMVYSYFSEHNNEKEYEE
                     LQQIREAIKGYDYKELSFPVLKYNREVLLSVKNYNKLSKELGLDKISSKLEKYEGIII
                     PSSNSQEHINSLKQLKNYSIKNLNIEVKKSKNKIIFPTGLFSKVVVISDDLYNEVKGE
                     FSKINFHGFDYKNWQSSAQITENLKEKHFNLDREYNRSYFLTLPDMYLVELQQSKILQ
                     FMGVFIGVILFIAVFSFLYFRLYTDEIEDNVKYKKLSKIGLSFKNMNKIVSIEIGTLF
                     FIPYFIAIINSIISLLFLNQVLNNSFKLENLGILLLISSIYSLYFYLLKKIYTRKVWF
                     FD"
     gene            8194..9585
                     /locus_tag="PC465_003281"
     CDS             8194..9585
                     /locus_tag="PC465_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2650561.1"
                     /translation="MENQQLLGTERISKLLLKYSIPAIIGMLVNSLYNVVDRIFIGNI
                     PGVGPLAITGLGVTMPIMTIILAFGMLIGIGTTTTISIKLGQGKVEEARKLIGNAMTL
                     SVITGIIIMILGILFANKILTLFGASENTLIYAKSYINIILLGTVVNLLSFSLNHSIR
                     ADGSPKISAGIMIVGCLTNIVLDWILIFGFNLGIQGAAIATVTSQALTAILTIGYYIS
                     GKSNLRFSKSNLKLDKKLIKAVFAIGMSPFAMQLAASLVQVISNIALKTHGGDLAIGA
                     MATISSIAMVFLMPIFGINQGAQPIIGFNYGAEKYDRVKKAYLGSLVVATIILCMGMV
                     VVMLFPEAIIGIFNKDPELMNISVNGLRIYLLMLPIVGLSVTGTNFIQSIGKAKMAML
                     LSLLRQVILLIPAVLILPTFLGLQGVWTAQPVSDFIATVITGIVVFRELKRYTPKTEK
                     LNENERLNEITTE"
     gene            9692..10732
                     /locus_tag="PC465_003282"
     CDS             9692..10732
                     /locus_tag="PC465_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDF2650562.1"
                     /translation="MEFTKKSKLKNMYVNMNVARMLSKINEYKGRQLLYKKQPKEILE
                     NLEKKSLVDCSESTYIGNQRDSSNFNLEKLISNEVTPRSREELSIVEYRDVVKTINSA
                     YESIPISSQTILELHGYLYKFSSTRGGSYKSDNDFIEHNLKPSEFISTDSSVNKVEKA
                     IEEICEAYNTLIEEDEIDILILISAFVLDFILIHPFKEGNIKMARVLILLLLNKNGYE
                     VGRYISLGKIFDDSSYEYYSNLNYLKASIGSEKADMNAWIEYFLETILTAYEKLDDSL
                     NISDKKRQTKTSRIEKIINSTLGYFTKEDIRDLCPDIPEPTINRVFNNLRKQDKIEVV
                     ARGRSAKWKKKY"
     gene            11221..11874
                     /locus_tag="PC465_003283"
     CDS             11221..11874
                     /locus_tag="PC465_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDF2650563.1"
                     /translation="MKKKLLYINVNSKPEDLSSSKTVARKFISKFMEKNKDFEVEEID
                     LYKEHIPRLEYQYFEKRNSIVSEENAKNLDDKDRKELTKIRNLCDQFVSASVYVIAAP
                     MWSLSFPAPLKEYIDCIIQDGKTISFEGNDKPQGILNDIDRSMVYIQSSGGHIPWVLK
                     PVMNKGLNYVESIMKFIGIKKFDELLVDGTGTSEEERQAAIEKASEKIDGIIDGMKF"
     gene            11950..12159
                     /locus_tag="PC465_003284"
     CDS             11950..12159
                     /locus_tag="PC465_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650564.1"
                     /translation="MREEKSNEKYDCYWCNQENNFCVEIKDNIVMIDDGTGTLKQAVF
                     IGYKQIQINLNCSHCQNLNRIKLNL"
     gene            complement(12299..12865)
                     /locus_tag="PC465_003285"
     CDS             complement(12299..12865)
                     /locus_tag="PC465_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HDF2650565.1"
                     /translation="MMNNELNTIILETLSNADITSNDIPSIDLYMDQIISLIDNKLSA
                     NKRFESDKILTKTMINNYSKEGLIKPVKGKKYTKEQILQMIIIYSMKNTLTIQEIKRI
                     LHGVYEKDNFSEKDLVSCYEKFMLIKENQRKNIPDFIESNFENISINPENKDDLLIAL
                     LSLTSMADQLKNISEKLVDRYFPDITKK"
     gene            13026..13679
                     /locus_tag="PC465_003286"
     CDS             13026..13679
                     /locus_tag="PC465_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HDF2650566.1"
                     /translation="MYQFFLKGRDPISSLTHFIGACLSLLATIILVFQSVTLQETSLL
                     MIVSVSVFGLSLIALYSASSYYHFLKGTPEQELFFRKVDHAMIYVLIAGSYTPICLNF
                     MEKKEGIIFVTAIWIVAFIGIIIKIFWMDAPRWLSTSIYLLMGWAIVFDINAFNSIPK
                     DCLRLLIMEGVSYSIGAIIYIIKKPNISPEFGFHEIFHIFIMIGSLFHFLAVLLYVL"
     gene            complement(13837..14013)
                     /locus_tag="PC465_003287"
     CDS             complement(13837..14013)
                     /locus_tag="PC465_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650567.1"
                     /translation="MYKYDDYVNLTNDLDLPVEIRNKCVRIVSVSENLEDIIIVHKFK
                     LYVVNEKYIKGIME"
BASE COUNT         5536 a         1399 c         2382 g         4830 t
ORIGIN      
        1 atatgaaagc tggtattgca atagattaaa gccttataca cgtttagttt ttaaagaaat
       61 tagtgttatt atgaaaacct aagttaattt attaaataaa taattgaata aaaaaatttt
      121 attatgtatt tataaaattt ttgttacaaa tttggcataa tatagtatac tttaagtgtg
      181 tattaggtta aatctataac aaattagacg tatgatatag acttagtgtt tattggcatt
      241 tacaagaaat ttgttaatat caactatttg tagtttgggc agttataatt attatagggg
      301 ggatgtccaa tacaaaacaa tcaaccaaga actaatatta tattataaag agttatagtt
      361 ttgtgtgttt atgtttttaa ttaaatttaa agtgggaaaa atatatttgt tagaatggag
      421 aatagcgaga tgagtaataa aatagttagt aagagacaat taacagatag tatttattta
      481 atggaaatag aggcacctag agttgcaaaa tcttctcaac caggtcaatt tataataatt
      541 aaaaatgatg aaaaaggaga gaggattcct cttacaatag ctgactatga tagagaaaaa
      601 ggaacagtaa ctattgtatt ccaaacagtt ggtgcttcaa ctaaaaagtt agcaatgttt
      661 gaagaaaacg attttgtaat ggattttgta gggccattag gacaagcaag tgaatttata
      721 catgaagata tagaagaatt aagaaataaa aagatattat ttgtagctgg tggagttggt
      781 tctgctccag tttatccaca agttaaatgg tttaaagagc atggattaga tgtagatgta
      841 ataattggtg caagaactaa agaattaatt atattagaag atgatatgaa aaaagtagct
      901 aaaaatgtat atgtatcaac agatgatggt acatatggat ttaatggaag agttacagac
      961 ctattaaaag atttagttga taatcaaggt aaaaaatacg accaagcaat agtaattgga
     1021 ccaatgataa tgatgaaatt tatgtgccaa ttaactaaag aactaaatat acctactata
     1081 gtaagtttaa atacaataat gatagatgga acaggtatgt gtggtggctg tagagttagt
     1141 gttggaaatg aaactaagtt tgcatgtgta gatggtcctg aatttgatgg tcatttagtt
     1201 gattttgatc aagcaatgag aagacagtct atgtacaaga ctcaagaggg aagagctatg
     1261 ctaaaacttg aagaaggcga tagtcatcat catagtaatt gtggatgtgg aggtaacaaa
     1321 taatggatgc taaaaaagta aaagtaccag ttagagaaca agaacctgct gtgagagcaa
     1381 caaattttga tgaggtatgc ttagggtata ataaagaaga agctatggca gaagctaata
     1441 gatgtttggc ttgtaaaaaa ccaaaatgtg tgggtggatg tccagtagga atcgacatac
     1501 cagggtttat aacaaaaatt aaagaagatg atatagaagg tgctgctaaa gtaatagcta
     1561 agagcagttc attaccagct gtttgtggta gagtatgccc acaagaaagt caatgtgaag
     1621 gtgtatgtat acttggaata aaatcagatg ctgtatcaat aggtaaatta gaaagatttg
     1681 tagcagattg gtcaaaagaa aatgacataa atttatctga tacagagcct aagaaaaatc
     1741 aaaaagtagc agtaatagga agtggtccag caggtctagc ttgtgctggt gatttagcta
     1801 aaaaaggcta tgatgtaaca atctttgaag caatgcatga gccaggtgga gttttaactt
     1861 acggaatacc tgagtttaga cttccaaaac aagctgttgt tcaacctgaa atagacaata
     1921 taagaaaatt aggtgtaaaa atagaaacta atgtaattgt tggtaaaaca attacagtag
     1981 atgaacttat agaagatgaa ggatttgaag ctatattcat aggttcagga gctggtcttc
     2041 caatgtttat gaatatacca ggggaaaatg caaatggagt attttctgca aatgagtttt
     2101 taactagagt aaacttaatg aaggcttata gagatgatta tgatacacct attagttctg
     2161 gtaaaaaagt tgctgtagta ggtggtggaa atgttgctat ggacgctgct agaactgcat
     2221 taagattagg ttcagaatca tatatagttt atagaagaag tgaaaaagag cttccagcaa
     2281 gagctgaaga agttcatcat gcaaaagaag aaggcattat atttaataca ttaacaaatc
     2341 ctaaggaaat tttagtagat gaaaatggat atgttaaagg tatggtttgt ataagaatgg
     2401 aattaggaga gccagatgat tctggaagaa gaagacctat agaaatagaa ggttctgaat
     2461 ttgtacttga tgtagacaca gttataatgt cacttggaac aagcccaaat ccactaatat
     2521 cttctacaac aaagagtctt gatataaata agaagagatg cttaataaca gatgaaaatg
     2581 gtcagacttc taaagagggt gtatttgcag gtggagatgc tgttactgga gcagcaacag
     2641 taatatctgc aatgggtgct ggtaaaacag cagcagcatc aatagatgaa tatttaaaag
     2701 caaaagttaa tgcttaattt gtaaattaaa gagagggtgt ctcaaaatga actttttagt
     2761 tcatgaggca ctctttttgt acaaaatcaa atatgtttta atcatttcaa caatgaaaat
     2821 ttcattcctg tagaaagtct aacttttagg tcttagtaca atctctattt tgatgtagcc
     2881 acttttttag atggtttaat aatttatcag ttattattgt aatatttgat actaagtaac
     2941 ataactttgt ctaactatga taaaatagtt atacaataaa ggtcttgtaa ggagtgaata
     3001 atgtgtggct aataaaatca gatttgtcaa atctaacatt aaataataga aaaataaatt
     3061 gtgtaattaa tggtatttta atatgaaaaa aagagaaaaa gtatttgatg ggctagtttt
     3121 taagcatata ttaatcttat taatactatt agttttgatt gatttaacaa gtaccatcat
     3181 atatgcaagt aactctatgg aaattacttc tagaaatatg attgaggcat caaaaagaga
     3241 acttgaaaac tatttagaag taaacatatc tttattaaaa gctcttagtc aagatgatag
     3301 attttctaat ggtgaaacat cactaattga aaagggaaaa ttattaagtc catatcaaaa
     3361 ggaatataat ctttttatga ttggtataac agatacaaaa ggaaatgctt caagtacata
     3421 tagggaaaat gttaactcaa taaaagataa gcctagtttt gagaaagcaa ttaaaacaaa
     3481 gcaagtagta gtttcagata ttgaagtcag taatgtaaca ggtgacaaag tatttatcat
     3541 atatgtacca attgtaaaaa ataatgagat gattgggacc atttttgctt ctttttattt
     3601 tcaagatgta aataatttaa taagtagaag caattttgat gattctatta aatttctaat
     3661 gatagataaa gattatacta ttatttctca tccaaacaaa aaatatgtaa atgataaaag
     3721 taagatgctt gatttagaag ggaatattat aggaaccact aaaagtgaaa tcttaaaaaa
     3781 tataaataaa aaatgtcaag gtgatttttt atcttgggat aattggagat tatataatgt
     3841 aaaatatacg aacataaagt ggactaattg gactttagta tcaaaatgta atatatttaa
     3901 gaactttaaa aatctaatag ttaattttat gataaagttg tatttttata tagtaatatt
     3961 tatgatattg tggaaattaa gtaatgctaa attaatagaa caacttaaaa aattggctta
     4021 ttatgattct ttaagtggaa taaaaaataa agaaaagttt agaaaagatt ctatgtatat
     4081 tttaaagaat tattatcaag ataattttta cttagtacaa ttggatgtca ataaatttaa
     4141 atatataaat gagatgtttg gatatgctga agggaataag atattaattc atatatcaca
     4201 agttttaaat aataatacaa ataaatatga aatttgtgct aggatggata atgaccattt
     4261 tatattgttg attgcttgta acactgaaga tgaactttta aatagattat ctaaaataaa
     4321 taaagaaatt tgtaacttaa atactactaa ctcatctaag tataaaattg ttatgtcaag
     4381 tggaatatat aagattacta aaaaggatga tattaaaaag attgacttgt taattgatag
     4441 agcaaatatt gcagcaaaaa gtaaaaagga aaaatatgaa cattcatatt cattttttaa
     4501 tgaagataca agaaatcgat tgtacaagga aaaacgattg gaagataata tgaataaagc
     4561 tttagaaaaa ggtgaattta tagtatatta tcaacctaag tatagtttag atgatgtaaa
     4621 tgaaattgaa ggagcagaag ccttgataag atggaatagt ccagaatttg ggtttatttc
     4681 acctatagat tttgtacctt tatttgaaaa gaatggtttt attgtaaata ttgatatgtt
     4741 cgtgtttgaa gaagtatgca aaacattaaa caagtggata aataaagggt atactcctgt
     4801 accaatctct gtaaatatgt ctagagttca tttatatagg gataatttta tagaaaatat
     4861 aactgatttg ataagtaaat acaatatatc tcctgagttt attgagcttg aactaacaga
     4921 aagtgttgtg tttgataatt taaatatatt gattgatata atgaaaaaga ttaaagagat
     4981 aggattcctt atatcaatgg atgattttgg ttcgggatat tcatctttaa atctgttaaa
     5041 agacctttct tttgatattt taaaattaga tagaggattt ttaatcgaaa caacagatac
     5101 aaaacgtgga aaaattatta tttctaagat tgtggaaatg gcaaaagcga ttgatattaa
     5161 agtaatctgt gagggcgtag aaacttatga acaagtagag ttcttgaaag agataggttg
     5221 tgataaggtt caaggatact tatttgctaa acctatggta ttagatgaat ttgaaaaaca
     5281 cttaaacttt aaatttgatt aatcattaat aattattaga ctataagata ccctaacaac
     5341 ttacttacaa atatgtaagt taattgttag ggtattttta tggttaaagt agtatattca
     5401 cgatattatg gtattgtagt aaaaataaaa aattatggag aatataaaat gaacatattg
     5461 agtattagaa atatatcaaa aacatattgc ggaaatattc catttaaagc attagataag
     5521 gttagtctaa atatagaaaa gggagaattt gtgtctgtta tgggaccatc tggaagtggt
     5581 aaatctactc ttttaaatat aatatctaca gttgatagac agagtgaagg tgaggttgta
     5641 ttagatggat atgatgtaag taaattgaaa ggagaaaaac ttgctgaatt tagaaggaaa
     5701 caacttggtt ttgtatttca ggattttaat ttgattgaca ctttaactgt tggcgaaaat
     5761 attatgttgc cacttacact agagggggaa agtatcaaag atatgaatat acaaactaaa
     5821 agtatatcta aatttttagg aatagataaa attttagata gaaaaaccta tgaaatttca
     5881 ggaggtcaag ctcaaaggtg tgctattgct agagctatta taaataaacc tgccatactt
     5941 cttgcagatg agccaactgg aaatcttgat tcaaaatcta ctgatgatgt tttgaaatta
     6001 tttactagga taaacaaaga acaaaaggta acaacactta tggtaactca tgaagcatat
     6061 agtgcaagtt attcagatag agtaattttt ataaaagatg gttgtatata tacagaaata
     6121 aaaaaatctg aaagcagtaa ttctttctat tctgatatac tagctgtttt gtctcaaata
     6181 ggaggtgtaa gatagtggat tttagaaagt ttgcttataa taatatagtt agaaatttca
     6241 gggcatattt agcatatttt ttaagttctg ttttttctat aatgatattt tttgtttttg
     6301 cagtgtctat gttccatcca attataacaa aatctggaat gcagagtggt tctactgcat
     6361 ttatggctct tatgacttca gaattaataa tattcggttt tagtctactt tttatattgt
     6421 actctttagg aaatttctta aaatatagat tgaaagattt tggagtattg atgataattg
     6481 gaatgagtaa cagacaactg aaaaaattga tattaattga aaatttgata ataggatttt
     6541 tagcagtgat gttaggaata ttacttggtt tatcaatttc aaaattgttt ttattgtatt
     6601 taagcaaact gttttatatg aatttaactg aattttattt tccagtaaaa gcaatgctat
     6661 tgactattgt atcatttatg attttatttt tgataacagg accaatgagc ttaaaattat
     6721 tgagtaaaaa gagcatttta gagcttttag taggtacaaa aaagcctaaa aaagagataa
     6781 aatcttcaaa gctatttgga ataattggtg taatatgtct tatattagga tatgctatga
     6841 tactatttgg caataagtta aaaataaatg gaggtatgta tacaacagca ctattaatta
     6901 ctttggggat atttttattt ttttctcaat ttactatttt gatattaaag tatttaaaaa
     6961 ataaagaaaa attttataag aacaaagtaa atatgttact tataagtaat ttgatatata
     7021 aattaaagga taatacacga ttgttatttt taataacaat acttttatcg gctactttag
     7081 tagcatttac aacaacttca acacttgtaa gttctcaagg agaagcttct aaaaataatt
     7141 tcccaatggt ttactcatat ttttcagagc ataataatga aaaagaatat gaagaactac
     7201 aacaaattag agaagcaatc aaaggatatg attataagga gttaagtttt cctgtactta
     7261 aatataatag ggaagtctta ctaagtgtaa agaattataa caaattatca aaggaattgg
     7321 gattagataa aattagttca aagttagaaa aatatgaagg gattataatt cctagtagca
     7381 attcgcaaga acatataaat tctttaaaac aattaaaaaa ttatagtata aaaaatttaa
     7441 atatagaagt aaaaaaatca aaaaataaaa taatttttcc tacaggactg tttagtaaag
     7501 ttgtagttat aagtgatgac ttatacaatg aagtaaaagg tgaattttca aaaattaatt
     7561 ttcatggatt tgattataaa aactggcaaa gcagtgcaca gataactgaa aatttaaaag
     7621 aaaaacattt taatttggat agagaatata acaggtcata ttttttaaca ttaccagata
     7681 tgtatttagt agagttacaa caaagtaaaa ttcttcaatt tatgggtgtt tttataggag
     7741 tgatattatt tatagcagtt tttagttttt tatactttag attatataca gacgagatag
     7801 aagataatgt aaagtacaaa aaactatcaa aaataggtct atcttttaaa aatatgaata
     7861 agattgttag tatagagata ggtacattgt tttttatacc gtattttata gcaattataa
     7921 atagcataat ttctttactg tttttaaatc aagtattaaa taatagtttt aagttagaaa
     7981 atttgggtat attactactg atatcatcta tatattcact ttatttttac ttattaaaaa
     8041 aaatttatac tagaaaagtt tggttttttg attaaagtgg tatataatag atatataaat
     8101 taatatttaa aaagtagtta atattagggg agggcatttg cacctccctt gtaatatgtg
     8161 gaaaattgaa tattagaaga aggaggagac ttgatggaaa atcaacaatt attaggaaca
     8221 gaacgaatta gtaaattact actaaaatat tctataccag ctataatagg tatgttggta
     8281 aatagtttat ataatgtagt agatagaatt tttattggaa atataccagg ggttggacca
     8341 cttgcaataa caggtcttgg tgtaacaatg ccaataatga caataatact tgcatttggg
     8401 atgttgatag gtataggaac tactactacc atatcaataa aacttgggca aggtaaagta
     8461 gaagaggcaa gaaaacttat aggaaatgca atgacgttat ctgtaataac aggaattatc
     8521 ataatgatac ttggaatatt atttgcaaat aaaatactta cattgtttgg agcaagtgaa
     8581 aatactttaa tatatgcaaa atcatatata aatattatat tattaggtac agtagtaaat
     8641 cttctttcct tttctttaaa ccactcaata agagctgatg gtagtcctaa aatttcagca
     8701 ggaataatga tagtaggatg tttaactaat atagttttag actggatatt aatatttgga
     8761 ttcaatttgg gaatacaagg agctgcaatt gctacagtaa cttctcaggc tcttacagct
     8821 attttaacta tagggtatta tataagtgga aaatcaaact tacgattcag taaatctaat
     8881 ctaaaattag ataaaaagct aataaaagca gtgtttgcaa taggtatgtc gccatttgct
     8941 atgcaacttg cagcaagttt agttcaagta atatcaaata ttgcacttaa aactcatggt
     9001 ggagatttag ctataggggc tatggctact atttcttcta ttgcaatggt atttttgatg
     9061 cctatctttg gaataaatca aggagcgcaa cctattatag gtttcaatta tggagctgaa
     9121 aaatatgata gggttaaaaa agcatattta ggttcattag tagtagctac tataatttta
     9181 tgtatgggta tggtagtagt tatgcttttc ccagaagcta ttataggtat atttaataaa
     9241 gaccctgaac ttatgaatat atctgttaat ggattaagaa tatacttact tatgttgcca
     9301 attgtaggct tatcagttac aggaacaaac tttatacaat ctataggaaa agcaaaaatg
     9361 gctatgttat tgagcctttt aagacaagta attttattga taccagcagt attaattctt
     9421 cctacattct taggcttaca gggtgtatgg acagctcaac cagtgtctga ttttatagct
     9481 acagtaatta caggtatagt tgtatttaga gaattaaaaa gatatactcc taaaactgaa
     9541 aaattaaatg aaaatgaaag actaaacgag ataactactg agtaaaaata taaattcaga
     9601 taattgagca agaaattgca aaaaatacga ttatatgata aaataaaacc gctgtcaagg
     9661 ataagagaaa ttctaattat ggagtgattt tatggaattt acaaagaaaa gcaaattaaa
     9721 aaatatgtat gtaaacatga atgtagctag aatgttgtct aagataaatg agtataaggg
     9781 tagacaactg ctttacaaaa aacaaccaaa agaaatttta gaaaacttag aaaaaaaatc
     9841 tttagtagat tgttctgaat ctacatacat tggaaatcaa agagatagta gtaattttaa
     9901 tctagaaaag ttgataagta atgaagttac acctagaagt agagaggaat tgagtattgt
     9961 tgaatacaga gatgtggtaa aaactattaa cagtgcttat gagagtattc ccatcagttc
    10021 acaaacgatt cttgagcttc atggatactt atataaattt tcatctacta gaggaggaag
    10081 ttataagtca gataatgatt ttattgaaca caatttaaaa cctagcgaat ttataagtac
    10141 tgattcaagt gtcaataaag ttgaaaaagc tatagaagaa atatgtgaag cttataatac
    10201 attgatagag gaagatgaaa ttgatatatt aatattaatt tctgcatttg tgttagattt
    10261 catattgata catccattca aagaaggtaa tataaaaatg gcgagagtac ttatcctatt
    10321 gttactaaat aaaaatgggt atgaagttgg aagatatata agtttaggaa agatatttga
    10381 tgatagttca tatgaatatt atagtaattt aaattatttg aaagcctcaa taggtagtga
    10441 aaaagcagat atgaatgcat ggattgagta ttttttagag acgatattaa ctgcatatga
    10501 gaagctggat gatagtttaa atatatctga taagaaaaga caaacaaaaa ctagtagaat
    10561 agagaaaata ataaattcta cccttggata ttttacaaaa gaagatataa gagatttatg
    10621 tcctgacatt ccagaaccta ctataaatag agtttttaat aatctaagaa aacaagataa
    10681 gatagaagtt gttgcaagag gaagaagtgc aaaatggaag aaaaaatatt aaaaaatgtt
    10741 tagataacta aaatggtata gtgttttaca ctataccatt tttaatgtca ttagcatgag
    10801 caataattta acaacttaag taatatcaat tttatttatt gattattttt gaactgaaaa
    10861 atggcgttat atggtatacc tcagtggtaa ttaattttgg atgagaagat ataatattac
    10921 agaatatatt aggagtatat gtagaaaaaa tataataaaa gtgtgaggct tagtaattaa
    10981 caaattatgt ggcttcacac ttttttataa aataaagata cttagcagaa taatatttta
    11041 gttgatatgt ttataagatg gtacttgttt gggtaaaagt ataaatagta aaaaagtaga
    11101 agtaatgtgt ataaaaacat aagttacatt ctgtaataat agttatttta taattcaaca
    11161 aaagaataga atgggtatat ttgtgaaata ataatataaa ataatcttag gagtgagctt
    11221 atgaagaaaa aattattata tataaatgta aattcaaaac ctgaagactt atcttcaagt
    11281 aaaactgtag caagaaaatt tataagtaaa tttatggaaa aaaataaaga ttttgaggtt
    11341 gaagagatag acctttataa agaacatata ccaagacttg agtatcagta ctttgaaaaa
    11401 agaaatagca tagttagtga agaaaatgct aaaaatttag acgataagga tagaaaagaa
    11461 cttacaaaga ttagaaatct ttgtgaccaa tttgtgagtg caagtgtata tgtaatagca
    11521 gcacctatgt ggagtttatc ttttccagca ccacttaaag agtatataga ttgtataatt
    11581 caagatggaa aaactatatc ttttgaaggc aatgataaac cacaaggaat tttaaatgat
    11641 attgatagaa gtatggtata tatacaatct tctggtggac acataccatg ggtgttgaag
    11701 ccagttatga ataaagggtt aaattatgtg gaaagtatta tgaagtttat aggaattaaa
    11761 aaatttgatg aattgttagt agatggaact ggaactagtg aagaagaaag acaagctgca
    11821 atagaaaaag catctgaaaa aatagatggt ataatagatg ggatgaaatt ttaattataa
    11881 tattttatta aaaatataaa ggaaaaacct cttttaatgt agaaacttat attgaaggag
    11941 gcgagaatca tgcgagaaga aaaaagtaat gaaaagtatg attgttattg gtgtaatcaa
    12001 gagaataatt tctgtgtaga aataaaagat aatatagtca tgatagatga tggcactggt
    12061 acgttaaaac aagccgtttt catagggtat aaacaaatcc aaattaattt aaattgttca
    12121 cattgtcaaa acttaaatag aataaaatta aatttgtaga attttaaaat ggaaattatt
    12181 gaaggaatta aaaatagaaa gtgttaatat ttagactgaa aattatattt tatacaataa
    12241 aagtttattt aaataacatt gtattttaat atttattttc agtcttactt tattaaaatt
    12301 attttttggt tatgtctgga aaatatctgt ctactaattt ttctgaaata ttttttaatt
    12361 ggtcagccat tgaagtcaga cttaataagg ctatcaataa atcatcttta ttttctggat
    12421 ttatactaat attttcaaaa ttagactcta taaagtccgg tatattcttt ctttgatttt
    12481 cttttattaa catgaatttt tcgtaacatg aaactaaatc tttttcactg aaattatcct
    12541 tttcatacac accatgtaag attcttttaa tttcttgtat tgtaagtgta tttttcatag
    12601 aataaataat tatcatctgt aaaatttgtt ctttagtata cttttttccc ttaactggtt
    12661 tgattaatcc ctctttgctg taattattta tcatggtttt agtaagaatt ttatcacttt
    12721 caaatctttt attagcagaa agcttattgt caattagaga aataatttga tccatatata
    12781 agtcaataga tggaatatcg tttgaagtta tatctgcatt acttagtgtt tctagtatta
    12841 tagtattaag ttcattattc atcatatgtt acctccataa tatatataat acactaaatt
    12901 agaaagtaaa acaatattaa ggcttgtaaa aaaaacataa agtggtataa ttaaatatat
    12961 aatatagtaa tggaaactat atttgtgaat ctgattttta aaatacataa ttgtaggagg
    13021 acgaaatgta tcaatttttt ttaaagggta gagacccaat aagcagttta actcatttta
    13081 taggtgcttg tttatctctt ttagcaacta taattttagt ttttcaatct gttacattac
    13141 aggaaacttc tctcttgatg atagtatctg tatctgtatt tggactttca ctaattgctt
    13201 tatatagtgc aagttcgtat tatcattttt taaaggggac accagaacaa gaattgtttt
    13261 ttagaaaagt agaccatgca atgatttacg tattgattgc tggctcttat acaccaatat
    13321 gtctgaattt tatggaaaaa aaagaaggca taatatttgt tacagcaata tggatagttg
    13381 catttattgg cataataata aaaatatttt ggatggatgc acctagatgg ttatctacca
    13441 gtatatattt acttatgggg tgggcaattg tttttgatat aaatgcattc aattcaattc
    13501 ctaaggattg ccttagacta ttaattatgg aaggtgtatc ttactctata ggtgcgatta
    13561 tttatataat taaaaagcct aatataagtc ctgagtttgg atttcatgaa atatttcata
    13621 tttttattat gataggttct ttatttcact ttttagcagt tttattgtat gttttatagt
    13681 tttaaaagat ttgattaatt gatactaaaa ttctacaatg aataaaatgg aactgcctta
    13741 tatagattat atcttagaca ataagacagt tccttattat aaatattaaa ttctacttat
    13801 aataaaattt tgataaaaat agtccattca aaatgcctat tccataattc ctttaatgta
    13861 cttttcattt acgacatata gtttgaattt atgtactata attatatcct ctaaattctc
    13921 tgaaacacta acaattctga cacatttgtt tctaatttct acaggtaaat ctaaatcatt
    13981 tgttaaattc acatagtcat catatttata cataaaatca tccctttaca ttaagatata
    14041 cttattatac tatattttaa taagtttttt taaattatta caatttttcc cgaaatttca
    14101 ttttttatac ataaaatttc caaattaggt aaagattaaa tttttta
//
LOCUS       DAMJXI010000088        14146 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.093, whole genome shotgun sequence.
ACCESSION   DAMJXI010000088 DAMJXI010000000
VERSION     DAMJXI010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14146
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.093"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            248..949
                     /locus_tag="PC465_003288"
     CDS             248..949
                     /locus_tag="PC465_003288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HDF2650568.1"
                     /translation="MKFQEMINSPGLWIVSSFLVIISVVQAIVFMKEALKEASNLGIE
                     RKGIKAAIRSASVTAIGPSLSPVITLLSLVAVIGAPTTWMRLCDVGAARTELGVISLT
                     SNLSGVEVGSAAFGAEAFSYALWGMALNNLGWLFVVFILGHRMRGIVEKMNMKYNPTW
                     VKKLLAGATVGLFAYLLSNQIKTFEIPKLTPAIISAIVMLVLTTLFKKNQRLQELSLG
                     IAMLIGMFGTQIILS"
     gene            975..1631
                     /locus_tag="PC465_003289"
     CDS             975..1631
                     /locus_tag="PC465_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650569.1"
                     /translation="MYDKKMIKIGRISIGLAIIANFIPAIYVGIRFGQMPMLSVIFQI
                     WGLVAATYGVSWIVQPIAYYPTLGAPGSYIGWLAGSVGDIRMPAASMAQKIAGVEAGT
                     HEGEVVGTIGTCCSIFVSASMITIFTIVGYKVIPLLPEFVTNSFNYILPALFGAIYVD
                     IARKDIRAGGCTIAVALAIMYFGEKIGIPGGLLTLFIVLGGILITRVFFVIDNNKTKE
                     "
     gene            1736..3376
                     /locus_tag="PC465_003290"
     CDS             1736..3376
                     /locus_tag="PC465_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HDF2650570.1"
                     /translation="MFDVKIVNGIIVDGTGNSRYKSDVGIVGDKIMAIGDLSQKEAKE
                     TIDATGKFVSPGFIDFHTHSDLSLVYDKYTRSRIHTGVTTDVIANCGIGVAPIREEKK
                     QELIDYLGTRIIGTIPTKLELHWNTMQEYFDYLTENSPAVNVVAYVAQGPVRINEMGF
                     SKEPATLEQLKNMKLEVRKAMEAGCVALSSGLVYLPGAYTKKEEMAELCKELIPYNGY
                     YISHIRDEGDEEMEALDEAIYIAKTAGVPLHVSHLKVMGHKNFGTIDEVFKKLDEAEA
                     DGLEVTFDCYPYTAGMTSLGALLPPWAFEGGVENMVKRLEVQENRDRIIKELEEGIPG
                     WQCFYQLAGGWNGVVLASVMTEANKYVEGKTLMEVAKINGENPFDTFFRLLIEEKSKI
                     QVVVHTQGQEDTDKVVCHPKSCIGSDSMDLSTEGLLSLGKPHPRAFGTFGRIFSYYVR
                     EKGMLTFEEAVKKITYLSAKRLGIYKERGLLKENYFADIVVFDPDTIEDKATYSNPKQ
                     YTVGVEYVLVNGKIALAGGKQTDVCAGRVIKNPLSIAK"
     gene            3734..5056
                     /locus_tag="PC465_003291"
     CDS             3734..5056
                     /locus_tag="PC465_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650571.1"
                     /translation="MKILYVGPGMVIDKILAVSKKNFPNIEADFLRYDRYIEVPDLLE
                     KYRGRVDAVLFTGKSPFKFFEKRQKDFVLSDYIPRHETTLYRVLLEITYLLKFDISRL
                     SIGTYDKAMMKRLYKEIGVEFKDEHMFFAEQKYLEEDYIKFVLEFHKYNYQNNDVCCC
                     ITGLEEAYHIMKKDNIPVVLALPSEDVMVQSIKNIQMRYIAKKNNENQIIVLAIKLNM
                     PSEYSLMKEDEYAYLSQRIKILDKLYHFNSRIDGVLVEQSRSEFMIFTTKKILELETK
                     KYRDIYLLDMIREVSVINTYIGIGYGKTANEAKFNAYESIKMAQSQKNDAAYVVFENG
                     EIMGPLKPNPTVKEKNSFDERFYQIATETGLSANTVYKVFNKIINSGKTEFTSKELAT
                     ICGVSIRTMDRIILRLCDSGYCEVVSEQLMSKYGRPSRILRFKPFLLF"
     gene            5253..6260
                     /locus_tag="PC465_003292"
     CDS             5253..6260
                     /locus_tag="PC465_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HDF2650572.1"
                     /translation="MGKYQDSKKVVRNYFEALENATGDEVENVLKQHMKSDYNWKGVY
                     PFREQEGTENVADVFWKPLKKSLSNMQRRQDIFIAGTNEIDNSEWVMSMGHFMGLFDK
                     DWLGIKHTRKMISLRYAEFNCVQDGKIAKTGLFVDIIGFMIQAGVNPLPPQTGSYFVY
                     PGPIDHNGLLFEDADEVEGVKTLALVNKMVDDLSELNESGAMGCPPEILEKSWAKDMI
                     WYGPGGIGASYTIPRYQEQHQLPFRNNLKGKTFNGHVCRFAEGNFACFFGWPNLTNVP
                     CGGFLGLPGGEVKADMQVVDVYYRKGDKLQENWVLIDIPYWLKQQGLDILERTKSIFN
                     A"
     gene            6298..7710
                     /locus_tag="PC465_003293"
     CDS             6298..7710
                     /locus_tag="PC465_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ester cyclase"
                     /protein_id="HDF2650573.1"
                     /translation="MASTNKNNATSKEEEKEVSTSGLESCTVKENKAKMNQTNFSNIN
                     ENQTNENKTNTYKGNIDKGNIDKTNTNKSDINKVNIDTVDTDKLNTNTLTKKNKKVIF
                     KGEDNMSSTKIYYGDSLEVTPVGVMDYNDFSKQTKREQEIPGFDSKYRDFVDYIMKIT
                     HNIWEEKGIGVIYDTYHNNVTMHCGSSNLVGIKDVISNTLQTLHAFPDRRLIGQNVIW
                     SNFGADGFLSSHRVLSTATNLGDSNFGPATGRKINFRTVIDCATTNNRIHEEWLVRDN
                     LWIVTQLGLNPQEVAKGMAKASESKVLSLQSTYGICESMDGQFMPTKYQAKDDSVGEM
                     MLEMTSRIYNYKYINEVKKYYHDNAVVHFICDKDLNGYDEIQGMIVSLLASIPNGSYE
                     VERVTCNQREKNEGYDVSVRWRLRGINEGIGFFGQPSGKHIEVMGINHYHILQGKVKE
                     EWITFDGMDVLKQMYMGVEE"
     gene            7852..9117
                     /locus_tag="PC465_003294"
     CDS             7852..9117
                     /locus_tag="PC465_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2650574.1"
                     /translation="MKTTVEIENDIILGKDYSNLKRGIAFFSIALIYFFYCYNFMVGT
                     FIKPTMIYALADGGFGFSLKQTEEIFAVMSFGTIPGTFIFGVISTKIGKKRTLISVAL
                     LIGLTTFIPMLSPTNIMLWKIARLCTGVVLGGVFGTAMPLVADMFPSKYRGKLAAILT
                     ALFSLAMIFGGKVYGVLGDANWQILMYTAIIPPIVGAILAIFFVPDDLEYTKELVKKG
                     KETGEKISYISMYKGKYLWIGLGTILLSGANFTAYSAFSNNATTYLVTGIGMSAAVAG
                     SIYSLQGIGQLVGYLFWGSIADKFGRKIPFIGMALAAVFVFIYTKLGGDNTTTFYMIS
                     VLLGVAVGYSGAWGAYYTELFPSKYRSLSSGMSFNGGRIISTFAIPAIAGTASGTLGM
                     MTIFYISIAVFVAGAIVWLFLPETLNNKK"
     gene            9159..10757
                     /locus_tag="PC465_003295"
     CDS             9159..10757
                     /locus_tag="PC465_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HDF2650575.1"
                     /translation="MISSIDVCIIIGYLLLMLVIGYYSGKDNKNQEDYFLAGRSMPWI
                     PIALSVAATMISANGFIGGPGWAYVDGMYPVMVNITVPLAIFFALSITTPVIYKLKIT
                     SIYEYMGLRLGNYSRGLTIIQFFINSLIQASSMVYIPVLIIQMITGWSLYALVPIVVL
                     VSIIYTLLGGIKAVIWTDSIQMIVVISAVFIVIIVALKGMNLSFFDTLQIAQQSGKLN
                     TFDFSRDISVTNTFWATLIGGTVMWIRYFCFDQSQVQRVLTSKSLKCAKNSFVVSAFV
                     MNLVYYFMLLVGVILFVFYGGRTFETSNEIMITFILNELPVGAIGIIIAGVFAAAMSS
                     IDSILNSMTTVFTKDIYEFYFKKDNKESSLKVTMIITVVIGVVMTGFIIMGFGGSIKS
                     ILDLVGNYISYFAGPATGAFVLAMFTYKANDKGVSIGFIVGLVLGFFISNKYNVSWLW
                     NPAIGATITLIFGYIFSVILKKNHNADDIKKYTAFGMRNHLISQGMDKVDGVSIVPFS
                     LGKQELIVLAFFIIQYIILFLIQF"
     gene            10792..11814
                     /locus_tag="PC465_003296"
     CDS             10792..11814
                     /locus_tag="PC465_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2650576.1"
                     /translation="MNQKKVHYNKSATSKDVARLAGVSQSSVSRAFGSANGKGVKPEV
                     RERIFRVANEIGYVPNLVARGMISGKTNVIGLIVGDSLGPFYNRIINLFVEKIQEIGK
                     QCLVFKVPRQQSIDSIISKVIQFQVEAVIITASAMNKVMAETCEENNIPVILFNRFIP
                     GIKISTVYVDPIEGGGMAAEYLLKKGHKNIGYIQFTRETSEEMEKKIGFYSKLRQSGI
                     HNLKEESANYDYDSGYEAGKRMLALSNPPTAIFCTSDLIAIGVMDAARFEYKLRVPED
                     LSVIGYDDIQMASWKSYNLTTIRQPLDLLIEKTINILKSLLNEENPESVVEMLKPELI
                     ERGSTL"
     gene            complement(12335..13738)
                     /locus_tag="PC465_003297"
     CDS             complement(12335..13738)
                     /locus_tag="PC465_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2650577.1"
                     /translation="MKMLNNFFKKINNPAPVFAQTKMERDNQTDDSLSTKPKTTFRDV
                     AGLDEVKEELFEIVDFMKSPQKYQKMGAKIPKGVLFYGPPGTGKTLLASAVAGETNSS
                     FFNVTGSEFVEKYVGVGAKRVRTLFEKARKEAPSIIFIDEIDAVGAKRHLESNNEKDQ
                     TLNQLLVEMDGFNKDSNVLIIGATNRLDLLDEALLRPGRFDRHIHIGAPNYHTRFEIL
                     KVHTDDKPIDKSVNLELLAKKTHGFNGAHLSNIANEAAIFAVRDDSECITSEHFDKAL
                     ERVIAGLESKNSALVEKEKKIVAYHEAGHALVSDIVGICPIQKISIVPRGQALGYVLQ
                     LPDEDRYIYTKDELIGKIKILLAGKASEELIFNHKSTGAKDDLKKVTEIANQMVCEYG
                     MSNLGFMTIDGNDKTFLCDKVQKEANRIVEICYKETLEMLKDNLEDLHSVSKFLFEKE
                     TMTHEELKDLIGKEAVN"
BASE COUNT         4995 a         1673 c         2666 g         4812 t
ORIGIN      
        1 ataataaaag accttataag ttaattacag gttaaaaaaa taatatgtga attttctgat
       61 atttactaat tatgaataaa atatttaagt attaatgttt ttagtgagac tttaagacag
      121 ataatctcct attaaagata ctatatctta gataaaataa attaaaacaa tataaaaaca
      181 taacaagatt acagaaagaa agctcacaat aaaatgctga aaaatttatt ttaaggagga
      241 ataaagtatg aagtttcaag aaatgattaa tagcccaggt ctttggattg tttctagttt
      301 tttagtaatt atttcagttg ttcaagcaat cgtatttatg aaagaggcac taaaagaggc
      361 ttcaaatctt ggtattgaaa ggaaaggaat taaagcagca attcgctcag ctagtgttac
      421 agccattgga ccttctctat ctcctgttat tacattatta tcactggtag ctgtgattgg
      481 cgctcctacg acttggatga ggctctgtga tgtcggagca gctagaacag agcttggagt
      541 aatatctctt acatccaatt tatctggggt agaagtaggt agtgctgcat ttggagcaga
      601 agctttttcg tatgcactat gggggatggc tttaaataac ttaggttggc tatttgttgt
      661 atttattttg ggtcatagaa tgcgtggaat tgttgaaaag atgaacatga agtataatcc
      721 tacttgggtt aaaaaactac ttgcaggagc tacagttgga ttatttgctt accttctttc
      781 aaatcaaata aaaacatttg aaataccaaa acttacacca gcaattattt cagctatagt
      841 tatgctagta ttgacaactt tatttaaaaa gaatcaacga ttacaagaat tatccttagg
      901 tattgccatg ttaattggta tgtttggtac acagattata ttatcgtgat taaaacggat
      961 aagaggtgat aattatgtat gataaaaaga tgataaaaat agggagaatt tctataggtc
     1021 ttgcaattat tgcaaacttt attcccgcta tctatgtagg tattcgcttt ggtcagatgc
     1081 caatgctttc tgttatattt caaatttggg ggttagtcgc tgcgacttat ggggttagtt
     1141 ggattgttca acctatagct tattatccta cactaggagc tccaggttct tatataggtt
     1201 ggcttgcagg ttctgttgga gatatacgta tgcctgcagc atcaatggca cagaaaattg
     1261 caggtgtaga agcaggaact catgagggtg aagttgttgg aacaattggt acatgttgtt
     1321 caatctttgt atcagcttct atgattacca tttttaccat tgtaggctat aaagtaattc
     1381 ctttgttacc tgaatttgtt actaattcat ttaattatat acttccagca ttatttggag
     1441 caatttatgt tgatattgca cgtaaggata ttcgagctgg tggatgtacg attgctgtag
     1501 cgttagcaat tatgtacttt ggtgaaaaaa ttggtatacc aggtggatta ttaacattgt
     1561 ttattgtgtt aggtgggata cttatcacaa gggtcttctt tgtaattgat aacaataaaa
     1621 caaaagaata ggattgctta ttaaggagaa agactagaat tatttgttga gaaaaaagaa
     1681 taggattgtt tattaagaaa tatgaatata aataagtctt gaaaggagaa aaagcatgtt
     1741 tgatgttaaa attgtcaatg gaataatcgt tgatggtaca ggaaattcaa gatataaaag
     1801 tgatgtaggg attgtaggag acaaaatcat ggctattgga gatttaagtc aaaaagaggc
     1861 taaagagact atagacgcaa ctggaaaatt tgtatcacct ggttttatag atttccatac
     1921 tcattctgat ttatctcttg tgtatgataa atacacaaga agccgtatcc atacaggtgt
     1981 aacaacagat gttattgcaa actgtggtat aggagttgct ccgataagag aagagaagaa
     2041 gcaagagtta attgattatc ttggaactag gataattggt acaattccaa caaaattaga
     2101 gcttcattgg aatacaatgc aagaatactt tgattactta actgaaaatt ctccagcagt
     2161 caatgttgta gcttatgtag cacaaggacc tgtacgtatc aatgaaatgg gattttcaaa
     2221 ggaaccagct actttagagc aacttaaaaa tatgaagttg gaagttagaa aagctatgga
     2281 agctggatgt gtagctcttt catcaggatt agtttattta ccaggagcat acacaaagaa
     2341 agaagaaatg gctgaattat gtaaggaatt gataccatac aatggatact atatatctca
     2401 tattagagat gaaggtgatg aagaaatgga agctcttgat gaagcaattt atatagctaa
     2461 gactgcagga gttcctctac atgtttctca tttaaaagtt atgggtcata agaattttgg
     2521 aactattgat gaggtattta aaaagctaga tgaagctgag gcagatggtt tggaagtaac
     2581 ttttgattgt tacccatata cagctggaat gacatctttg ggtgcacttt tacctccttg
     2641 ggcttttgaa ggcggtgtag aaaatatggt aaaacgatta gaagtacaag aaaatagaga
     2701 cagaattata aaagagttgg aggaagggat tcctggatgg caatgtttct accaattagc
     2761 aggtgggtgg aacggtgttg tactagcctc tgtaatgact gaagcaaata aatatgtaga
     2821 gggtaaaact ttaatggagg tagccaaaat caatggtgaa aatccatttg atacgttctt
     2881 taggcttttg attgaagaaa aaagtaaaat tcaagtagtt gttcatacac aaggtcaaga
     2941 ggatacagat aaggttgttt gccatccaaa gtcatgtata ggttctgata gtatggacct
     3001 ttctacagaa ggtttacttt ctcttggaaa gcctcatcct cgtgcatttg gtacttttgg
     3061 acgaattttc tcttactatg ttagagaaaa aggtatgttg acttttgagg aagcagttaa
     3121 aaagataact tatctttcag caaaacgctt aggcatttat aaagaaaggg gtctacttaa
     3181 agaaaattat tttgctgaca ttgtggtatt tgacccagat acaatagaag ataaagcgac
     3241 ttatagtaat cctaaacagt atacagtggg agtggaatat gtgttggtga atggtaaaat
     3301 tgcattggca ggaggaaagc aaactgatgt atgtgctgga cgtgtaatta aaaatcctct
     3361 tagcatagca aaatagaata cattaagaac ttttataaaa atagtctttc tttgaatatt
     3421 aaggaaggct atttttgtta aattaataaa gattactcta cttgtgtttt ctaaagaatt
     3481 taactttaag tagaaaaaac aatatattaa ttgtaaaatg taattaatat taatgaataa
     3541 gatttaaata caaaaattta aatacaaaaa tgtttcaaca gatagtcgta attaaaaaac
     3601 ttaaagtaac tttttatatt aggtataatt gattattcaa aattctatga atcaggagtc
     3661 ctgtgccttt agtcatggta ggtttagaaa atgttttaag agataatagt atcattagga
     3721 aaggagagac gaaatgaaaa tactttatgt aggaccaggt atggtaatcg ataaaatact
     3781 agcagtaagt aaaaagaatt ttcctaatat tgaagcagat tttcttagat atgatagata
     3841 tattgaagta cctgatttat tggaaaaata tagaggtaga gtggatgcag ttctttttac
     3901 aggtaagtcg ccatttaaat tttttgaaaa aagacaaaaa gattttgtat tgtctgatta
     3961 tattcctaga catgaaacaa cattgtacag agtgttgctt gaaattacat atttgcttaa
     4021 attcgatatt agtagactta gtataggtac ttatgataag gctatgatga agagattgta
     4081 taaagaaatt ggagttgaat ttaaggatga acatatgttt tttgcagagc aaaagtattt
     4141 agaagaggac tatataaagt ttgtgcttga atttcataaa tataattatc aaaataatga
     4201 tgtatgttgt tgtattacag gtcttgaaga ggcctatcat ataatgaaaa aagataatat
     4261 tccagtagtt ttagccttgc cttctgagga cgtaatggtg caaagtataa aaaacattca
     4321 gatgcgttat attgcaaaga aaaacaatga gaatcagatt attgttcttg ctattaaact
     4381 gaacatgcct tcagaatatt cactaatgaa ggaagatgag tacgcttatc tttcacaaag
     4441 gattaagatt cttgataaac tataccattt caatagccgt atagatggtg ttttggtaga
     4501 gcagagtaga agtgaattta tgatttttac aactaaaaaa atacttgagt tagaaacaaa
     4561 gaaatacaga gatatttatt tgttggatat gattcgtgaa gtttcagtta taaacactta
     4621 tataggaatt ggttatggaa aaacagcaaa tgaagctaaa tttaacgctt atgagagtat
     4681 taagatggct caaagtcaaa aaaatgatgc agcatatgta gtttttgaaa atggagaaat
     4741 tatgggacca ctaaagccaa atcctactgt caaagagaaa aatagttttg atgaacgttt
     4801 ttatcaaatt gctacagaga cagggctaag tgctaatact gtatataaag tattcaataa
     4861 aataataaat agtggaaaaa ctgaatttac atcaaaggaa ttagctacta tatgtggtgt
     4921 aagtattaga actatggaca ggattatact tagattgtgt gattctggtt attgtgaggt
     4981 agtgagtgaa cagcttatga gcaagtatgg tagacccagt agaatattac gttttaaacc
     5041 ttttctgttg ttttaaatag atataagtca aaaattaaat ttttatgata acattttctt
     5101 tacaactttt tagatatatg ttaatattta gaaaaatgca tatgtattca taaaataaac
     5161 tcaaaacagc taaaaaatca ttaaaaagga aatcgtatgc ataaaatgag aaagttaatt
     5221 tataacttaa ataaatctgg gaggagataa ttatgggaaa atatcaggat tcaaaaaaag
     5281 ttgtaagaaa ttattttgaa gcattagaaa atgctactgg ggatgaggtt gaaaatgtct
     5341 taaagcaaca tatgaaatca gattataact ggaaaggtgt gtatccattt cgtgaacaag
     5401 aaggcactga aaatgtagca gatgtatttt ggaagccttt aaaaaaatca ttgagtaata
     5461 tgcaaagacg acaagatatt ttcattgcag gaacaaatga gattgacaat agtgaatggg
     5521 taatgagtat ggggcatttt atgggacttt ttgataagga ttggcttggc attaaacata
     5581 ctcgcaaaat gattagttta agatatgcag aatttaactg tgttcaagat ggtaaaattg
     5641 ctaaaactgg attatttgta gatataattg ggtttatgat tcaagcagga gttaatccat
     5701 tgccaccaca aacaggttca tattttgtat atccagggcc aattgaccat aatggattac
     5761 tttttgaaga tgcagatgaa gttgaaggag taaaaacttt agcactagta aataaaatgg
     5821 tagatgattt atctgaatta aatgaaagtg gtgctatggg atgcccacca gaaatacttg
     5881 aaaaatcttg ggctaaagat atgatttggt atggtccagg tggaattggt gcttcttata
     5941 ctatacctag atatcaagag caacaccagc taccatttag aaataattta aaaggaaaga
     6001 cttttaatgg gcatgtatgt agatttgcag aaggtaattt tgcttgtttc tttggatggc
     6061 ctaatctgac taatgtacca tgtggaggtt ttttaggatt accaggtgga gaggttaaag
     6121 cagatatgca agttgttgat gtttattatc gtaagggcga taaacttcaa gaaaactggg
     6181 tgttaattga tattccttat tggttgaaac aacaagggct tgatattctt gagagaacta
     6241 aaagtatttt taatgcttag ttatgcatac gtattctaaa acaaaggggg atataaagtg
     6301 gcatctacca acaaaaataa tgcaacaagt aaagaggaag aaaaagaagt ttctacaagt
     6361 gggcttgaat catgtacggt taaagaaaac aaagctaaaa tgaatcaaac taattttagt
     6421 aatataaatg aaaatcaaac aaatgagaat aaaacgaaca catataaagg aaatatagat
     6481 aaagggaata tagataaaac aaacacaaat aaatccgaca taaataaagt taacatagat
     6541 acagtggata cagataaatt aaatacaaat actcttacta aaaaaaataa aaaagttata
     6601 tttaaggggg aagataatat gtcatctaca aaaatttact atggagattc attagaagta
     6661 acgcctgttg gagtaatgga ttacaatgat ttttcaaaac agacaaaaag ggaacaggaa
     6721 atacctggat ttgattctaa gtatagagat tttgtagatt atattatgaa gattacacat
     6781 aatatctggg aagaaaaagg tataggtgtt atttatgata catatcacaa taatgttaca
     6841 atgcattgtg gctcttcaaa tttagttggt attaaagatg ttatttccaa tactcttcaa
     6901 acattacatg cgtttcctga tagaagatta attggtcaaa atgtaatatg gtctaacttt
     6961 ggtgctgatg gttttttatc ttctcaccgt gttttgtcta cagcaactaa cttaggtgat
     7021 agtaattttg gaccagcaac aggtagaaaa ataaacttta gaactgtaat tgattgtgcc
     7081 acaactaaca atagaatcca cgaagaatgg ttggttagag ataatttatg gattgttact
     7141 caattaggat taaaccctca ggaagtagca aagggtatgg caaaggcaag tgaatctaaa
     7201 gtgcttagtt tacaatcaac ttatggtatc tgtgaatcta tggatggtca atttatgcca
     7261 actaagtatc aagcaaaaga tgattctgtt ggcgaaatga tgcttgaaat gacaagccgc
     7321 atttataatt ataagtatat aaatgaagtt aaaaaatact atcatgataa tgcagtagta
     7381 cattttatat gtgataaaga tttaaatggc tatgatgaga ttcaaggaat gattgtaagt
     7441 ttacttgcat caattccaaa tggaagttat gaagtggaaa gagtaacttg taatcaaaga
     7501 gaaaaaaatg aaggttatga tgtatctgta agatggagat tacgtggaat aaatgaaggt
     7561 ataggatttt ttggacagcc ttctggaaag catatagaag taatgggaat caatcattat
     7621 catatactac aaggtaaagt aaaggaggag tggataactt ttgatggtat ggatgtatta
     7681 aaacaaatgt atatgggagt agaagaataa agctgtttag agtataaata gttttgaaat
     7741 atatagggaa gtattgcttt ataaaattta agtggggaat gtatatgaaa aatagatgtt
     7801 taaactttta gcaaaattat gactaaattt aaaaggggga attataaaaa tatgaaaaca
     7861 acggttgaaa tagaaaatga tatcatatta ggaaaagact attcaaacct aaaaagagga
     7921 attgcatttt tttcaattgc tttaatatac tttttttatt gctacaattt tatggtgggt
     7981 acttttatta aaccaacaat gatttatgct ttagcagatg ggggatttgg tttttcatta
     8041 aaacaaacag aagaaatatt tgcagttatg tcttttggta caattccagg tacatttatt
     8101 tttggggtga tttctacaaa aattgggaag aagaggactt taattagcgt tgctttactg
     8161 attggattga caacatttat accaatgtta tctcctacaa atattatgtt atggaaaata
     8221 gcacgtttgt gtacaggagt agtgttggga ggcgtatttg gaacagctat gcctttagtt
     8281 gcagatatgt ttccaagtaa atatcgtggt aagttagctg ctatattaac tgctttattt
     8341 tcattagcaa tgatttttgg tgggaaagta tatggcgttt taggtgatgc aaattggcaa
     8401 atattgatgt atactgcgat tataccacct atagttggag ctatcttagc aatcttcttt
     8461 gtgccagatg atttggagta tacaaaggaa ttagttaaaa agggaaaaga aactggtgaa
     8521 aagattagct atataagtat gtataaggga aaatacttat ggattggatt gggaacgatt
     8581 cttttatcag gtgcaaattt tacagcatat tcagcatttt caaataatgc aactacatac
     8641 ctagtgacag gaataggaat gtcagcagca gtggctgggt ctatatatag tttacaagga
     8701 attggtcaat tagtaggata tttattctgg ggttcaattg cagataaatt tggaagaaaa
     8761 atacctttta taggtatggc attagcagca gtgtttgttt ttatatatac aaaattaggt
     8821 ggagataata caacaacatt ctatatgata tcagtattac taggtgttgc tgttggatat
     8881 tctggagcat ggggagcata ctacacagag ttgttcccaa gtaaatatcg ttcgttgtca
     8941 tctggtatgt catttaatgg aggaaggatt atatctacgt ttgcaatacc tgctatagct
     9001 ggtacagctt ctggtacttt aggtatgatg actatctttt acatatcaat cgcagtcttt
     9061 gtagcaggtg ctattgtatg gttattctta ccagagacgt taaataataa aaaataaaat
     9121 actaggaatt tattttgtta cttagaaagg ggtggcttat gatttcatca attgatgtat
     9181 gtattataat aggatatttg ctattaatgt tagttattgg ttattattca ggaaaagata
     9241 ataaaaatca agaagattat ttcttggcag gtaggtcaat gccatggatt ccaattgctt
     9301 tatcagttgc agctactatg attagtgcaa atggctttat aggtggtcct ggatgggcat
     9361 atgtagatgg aatgtatcca gtaatggtta atattacagt acctttagca atattttttg
     9421 cactgagcat taccacccca gttatctata aattaaaaat aacctctata tatgaatata
     9481 tgggacttcg tttaggaaat tattcaagag gattaactat tattcaattt tttattaatt
     9541 cattgattca agctagttct atggtatata ttccagtgct tattattcaa atgattactg
     9601 gctggtcact ttatgcttta gtcccaatag ttgtacttgt atcaattata tatactctat
     9661 taggtgggat taaggcagtt atatggactg atagtattca aatgatagta gtaataagtg
     9721 ctgtatttat agtaattatt gtagccttaa aaggaatgaa tctaagtttc tttgatacat
     9781 tacaaattgc acaacagagt ggaaaattaa atacatttga tttcagtagg gatatttcag
     9841 tgacaaatac tttttgggct actttaattg gtggaactgt aatgtggata agatactttt
     9901 gttttgacca atctcaagta caaagagttt taacatctaa atctttaaaa tgtgcaaaaa
     9961 attcttttgt agttagtgca tttgttatga atttagttta ctactttatg ctattggtag
    10021 gagtaatttt atttgttttt tatgggggaa ggacatttga aacttcaaat gaaataatga
    10081 ttacttttat tttaaatgaa cttccagtag gagccattgg aattattatt gcaggtgtgt
    10141 ttgcagcagc aatgtctagt atcgactcta tattaaacag tatgacaact gtttttacga
    10201 aggatattta tgagttttat ttcaaaaaag ataacaaaga atcatcatta aaagttacaa
    10261 tgattataac tgtagttata ggagttgtta tgacaggttt tattattatg ggatttggag
    10321 gaagcatcaa atcaattctt gaccttgttg gtaactatat ctcatacttt gctggaccag
    10381 ctacaggtgc atttgtacta gcaatgttta catataaagc taatgataaa ggagtatcta
    10441 ttggttttat tgtagggtta gttttaggat tttttatttc taataaatat aatgtgagtt
    10501 ggttgtggaa tccagcaata ggtgctacaa taacattgat atttggatat atttttagtg
    10561 tcattttaaa gaaaaatcat aatgcagatg atattaaaaa atacactgca tttggtatga
    10621 gaaatcacct tatttctcaa ggaatggata aagtagatgg agtatctata gtgccatttt
    10681 ctttaggtaa acaagaacta attgtattag ctttttttat tatccaatat attatattat
    10741 ttttgataca attttaagaa gaaatactag atatttaagg agaaatacta aatgaatcaa
    10801 aagaaagttc attataataa atcggctacc tcaaaagatg ttgcaagatt ggcaggagta
    10861 tctcaatcat ctgtttcaag agcatttggt agtgcaaatg gaaagggcgt aaaacctgaa
    10921 gtaagagaaa gaatttttcg tgtagcaaac gaaataggat atgttcctaa tttggtagca
    10981 cggggaatga ttagtggaaa aactaatgtt ataggattga tagttggtga tagtctaggt
    11041 ccattttaca atagaattat caatttattt gtagaaaaaa ttcaagagat aggtaaacag
    11101 tgtctcgttt ttaaagttcc tagacaacaa agtatagata gtataatttc aaaagtaatt
    11161 cagtttcaag tagaagctgt gattattaca gcttcggcca tgaataaggt gatggctgag
    11221 acttgtgaag aaaacaatat tcctgtgatt ctttttaatc gttttatacc tggtataaaa
    11281 ataagtacag tctatgtaga cccaattgaa ggtgggggaa tggctgctga atatctgctt
    11341 aagaaaggtc ataagaatat aggatatatt caatttacga gagaaacaag tgaagaaatg
    11401 gaaaagaaaa ttggatttta ttctaagtta agacaaagtg ggattcataa tcttaaagaa
    11461 gaatctgcaa actatgatta tgattctgga tatgaagcag gtaagagaat gttagcatta
    11521 tcaaatcctc caacagcaat tttttgcaca agtgacttga tagctattgg tgtaatggat
    11581 gctgcaaggt ttgagtacaa gttgagggtg ccagaggatt tatcagtgat aggatatgat
    11641 gatattcaaa tggcttcatg gaagagttat aatttaacga cgattagaca gccactagat
    11701 ttgttgattg aaaaaacaat taacatactt aagtccttat taaatgaaga aaatccagag
    11761 tcagtcgttg aaatgttaaa acctgaattg attgaaagag gttctacact ttaagtggta
    11821 gatatttaat taagtgatag atatttaatt aagtggtaga tatttaatta agtggtagat
    11881 atttaattaa gtggtagata tttaattaag tggtagatat ttaattaagt ggtagatatt
    11941 taattaagtg gtagatattt aattaagtag tagataccta attaagttgt agatatctga
    12001 taagaaattt ttaagttttc aatcgttcta aattgtgagt ataaaaatct actaaattta
    12061 gttatgtaaa atataaatta taggtgtaga aactaggcta ctagctttta taccacttca
    12121 aacattactg gaggtagtta agtttacagc agtttagttt tatgtagata taatattctg
    12181 taaatagaca aaattaaaat atgtaagtgt ctcaaaatga aatttttagt ttatgaggca
    12241 cttttttgta taaaatcaaa tgtattttta taactttaac aataaaaaga ggcttatctc
    12301 tattttgaga cagcctcaaa tttttaaaac tatattagtt tacagcttct tttcctatca
    12361 aatcttttaa ctcttcatga gtcatagttt ctttttcaaa taagaattta gaaacagaat
    12421 gtaaatcttc aagattatcc tttaacatct ctaaagtctc tttataacaa atttcaacta
    12481 tacgatttgc ttccttttga accttatcac ataagaaagt cttatcattt ccatcaatag
    12541 tcataaatcc taagttactc ataccatatt cacaaaccat ttggttagct atttcagtga
    12601 ctttctttaa gtcgtccttt gcaccagtag atttatgatt aaatattaat tcttctgaag
    12661 cctttccagc aagtaatatt tttatttttc caatcaactc atccttagta taaatatatc
    12721 tatcttcatc aggtaattga agaacataac ctaatgcttg tcctctagga actatagata
    12781 ttttttgtat aggacaaatt cctactatat cacttacaag agcatgtcca gcttcatgat
    12841 atgctactat ttttttctct ttttcaacca atgcagagtt tttagattct agccctgcaa
    12901 taactctttc aagtgccttg tcaaaatgtt ctgatgtaat acactcactg tcatctctaa
    12961 ctgcaaatat agctgcttca tttgctatat ttgaaagatg agccccattg aaaccatgag
    13021 tttttttagc taaaagttct agatttacag atttgtctat aggtttgtca tctgtatgta
    13081 cctttagaat ttcaaatcta gtgtgatagt ttggtgcacc tatatgaatg tgtctgtcaa
    13141 atcttcctgg tctaagtaaa gcttcatcta ataagtcaag tctattggta gcacctatta
    13201 ttaatacatt ggaatcttta ttaaatccat ccatttcaac taaaagttgg tttagtgttt
    13261 ggtctttttc gttgttactt tcaagatgtc tctttgctcc tacagcatct atttcgtcta
    13321 taaatattat acttggagct tcttttctag ctttttcaaa tagagttcta actctttttg
    13381 ctcccacacc tacatatttt tcaacgaact ctgaaccagt aacattaaaa aatgatgagt
    13441 ttgtttcacc agctacagca gatgcaagta gggttttacc tgttcctgga ggaccataaa
    13501 ataatactcc tttaggtatt tttgcaccca ttttttgata tttttgtggt gacttcataa
    13561 aatcgactat ttcaaatagt tcttctttta cttcgtctaa tccagcaacg tctctaaatg
    13621 tagtctttgg ttttgtagaa agtgaatcat ctgtttgatt atctctttcc atttttgtct
    13681 gtgcaaagac aggagctgga ttgttgattt tcttaaaaaa gttgtttagc attttcatat
    13741 tcacacctca ggtaattaat tattgttaat caattttata ttttccatat ttactatttt
    13801 ttattattta tttttcatgg aaaaaatata catgttatct aaataaaaat aaatttgtaa
    13861 gatgtatgaa aaaatgaatt tatgtatata gagatttcta cttatgtatt gaataaagta
    13921 ttacaaatta taaattataa attatgtatt gattatatat tgagtaaagt attataaagc
    13981 atgtattgat taagtattta ttaagtattg aataaaatat tacaaattta gttgaaatga
    14041 aaatgataaa aaatgttgta ctatatttta caaatcatat aaatagagaa attgttgtag
    14101 cacaaagtag taggtagtat attagaatat aattatagga tttgtt
//
LOCUS       DAMJXI010000089        13469 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.094, whole genome shotgun sequence.
ACCESSION   DAMJXI010000089 DAMJXI010000000
VERSION     DAMJXI010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13469
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.094"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            234..2093
                     /locus_tag="PC465_003298"
     CDS             234..2093
                     /locus_tag="PC465_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2650578.1"
                     /translation="MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVR
                     GASQRLTKLEMNHQPNDELIEYIDEILQELITGHGDYGLVITDCNEYNEDLLLLEKKW
                     EDLNIEIKKVRMKEQNNQLLSISEEFFSLANDTVFKIENFSKEKSNYLMTLIIIISII
                     GILACIILILQYSKKMVRLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICIHKDK
                     KFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRC
                     YVDKEDLVVRQRDVDNELINITNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANF
                     AQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHSQKI
                     NCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFV
                     QISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQKHLLEIIHDLH
                     ENGFTCSLDDFGKGYSSLSVLKDLPFDVLKLDSMFFKASLDKDKEKIVIKNIVHMLKE
                     LNITTVAEGIECKEQVEFLRDIGCDLVQGFVFYKPMPILEFEKILDKEFVYNS"
     gene            complement(2385..2984)
                     /locus_tag="PC465_003299"
     CDS             complement(2385..2984)
                     /locus_tag="PC465_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2650579.1"
                     /translation="MAIELKKGQKINLTKKENSNLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNTQGENLRIN
                     GNKIKDIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(3087..3884)
                     /locus_tag="PC465_003300"
     CDS             complement(3087..3884)
                     /locus_tag="PC465_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2650580.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(3997..4102)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(4194..5180)
                     /locus_tag="PC465_003301"
     CDS             complement(4194..5180)
                     /locus_tag="PC465_003301"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HDF2650581.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYLSKTNTDNTNYCLSEHD
                     IKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVAFVENKLIGIRHEENALRNTLDSIEINDYFLGADTDILVSGILGVK"
     gene            5664..7394
                     /locus_tag="PC465_003302"
     CDS             5664..7394
                     /locus_tag="PC465_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HDF2650582.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKK
                     VDEAEIELVE"
     gene            7504..7584
                     /locus_tag="PC465_003303"
     tRNA            7504..7584
                     /locus_tag="PC465_003303"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7538..7540,aa:Leu,seq:tag)
     gene            7919..8434
                     /locus_tag="PC465_003304"
     CDS             7919..8434
                     /locus_tag="PC465_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HXXEE domain-containing protein"
                     /protein_id="HDF2650583.1"
                     /translation="MEKYIWLFPLLFIFHDMEEIIGFGIWLKKNKSMLDKKYPFISKV
                     YKNYSTEGMAFAVFEEFILCIIFCILTVITENQYVYLLWLGSFIAYTLHLVIHIGQSI
                     IIRKYIPSLITSIICLPISIWCISKSIYIVDCEMSTTILYSIIGIIIVALNLKFAQSL
                     IGKFTKWMSNI"
     regulatory      8926..9030
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            9240..11714
                     /gene="gcvPA"
                     /locus_tag="PC465_003305"
     CDS             9240..11714
                     /gene="gcvPA"
                     /locus_tag="PC465_003305"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HDF2650584.1"
                     /translation="MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHEKVRK
                     SAGIFDVSHMGEVQIKGAESEKFIQNLVTNDISTLKINDIIYTPMCYENGGVVDDLLI
                     YKFGEEDYLLVINAGNIDKDVAWIIKQSEGYNVDIKNISSEVSQLAIQGPKAEEILQK
                     ITDIDLNSIKFYKSIPSTKVCGCPCLVSRTGYTGEDGFEIYCKNKYVEIIWNEVLKVG
                     GEDICPAGLGCRDTLRFEAALPLYGHEINEHISPIEGGLSIFVKTNKESFIGKSILSK
                     EKESGAKRKLVGFEMQGKGMPRNGYDIRIGDKTVGFVTTGCASPTTGKILGMGIIDSE
                     YAKVGNEIGIAIRKKVVPAVIVKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKML
                     KVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLG
                     AGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANA
                     SMYDGATAAIEACIMAMNQTRKSKIVVSKTIHPETLSVLRTYLQYKDCEIVEIDFCNE
                     YGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLG
                     VLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDVEGK
                     IAYVLTLQTREQHVRREKATSNICSNQALNALVASIYMATMGKEGFKEVGMQSMKKAH
                     YTYNKLVQTGKYKPIFKGKFFKEFAVQGNLNIETINDKLLEENILGGYNLEYNYPELK
                     NSTLLCVTEKRSKEEIDKLVGIMEGL"
     gene            11714..13171
                     /gene="gcvPB"
                     /locus_tag="PC465_003306"
     CDS             11714..13171
                     /gene="gcvPB"
                     /locus_tag="PC465_003306"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HDF2650585.1"
                     /translation="MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIEDMIDPDMARQSE
                     LNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHP
                     YQSSDTAQGSLSLMYDLSRRLAEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDH
                     KRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEVLNDEVAALMLTNP
                     STLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGDMGFDVVHLNLHKTFST
                     PHGGGGPGAGPVGVKKELVPFLPIPVIERKEDKYVLNYDREKSIGKIKNFYGNFGVLV
                     RAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEA
                     NIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIEAMKSVAKEA
                     KEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR"
BASE COUNT         5064 a         1592 c         2211 g         4602 t
ORIGIN      
        1 tggtttgtaa ttaaaaagtt tataaattac attaagagta ataatctata agaacttata
       61 tattagaaaa aattttgtat atatagagga ctctaaagat gaactatgta aaacaaggtt
      121 tatatattct aattgtatag aaaatttatt gtaaacgcat gtatattatt agaaaaaata
      181 gtttgaaggt attcaataaa cataaaaaac aatatagggg ataaaggtgt tttatgaaga
      241 gatttttgag gagaattatc ttagttttat ttattttgtt gatttttata agttttattt
      301 ctattaaatt aattcataat gttggagatt atggaaaatt gattaattat gttgggattg
      361 ttcgtggagc tagccaacgt ctaactaaac tagagatgaa tcatcaacca aatgatgaat
      421 taatagaata tattgatgaa atcctacagg agttgattac agggcatgga gattatggtt
      481 tagtaatcac tgattgtaat gaatacaatg aggacttact tttattagaa aaaaagtggg
      541 aagatttaaa tattgaaatt aaaaaagtaa gaatgaaaga acagaataac cagttattaa
      601 gtataagtga agagtttttt tctcttgcaa atgatacagt gtttaaaata gaaaactttt
      661 ctaaagaaaa aagtaattac ttaatgactt taataataat tatatctatt ataggtatat
      721 tagcatgtat catattgatt ttacaatata gtaaaaaaat ggttagactg gaaaaattaa
      781 atgtagattt aaaaaatatt gcatataaag atgaactaac aggagtaaat actatagaaa
      841 aatttaaatt ggatgcaaat caaaatattt gtatacataa ggataagaaa tttgctgtat
      901 tctatattga ttttgaaaac tttaaataca ttaatgatat atttggatat gattatggtg
      961 acatgatact gaaaagatat gctaatctta tgatgaatga catagggaaa tatgaaatat
     1021 ttgcaagaga aattgcagat agatttgttg cgttaagatg ctatgtagat aaggaagatt
     1081 tagtggtaag acaacgagat gtagacaatg aactaattaa tataacaaat gaaattaaaa
     1141 ataaacatag tattactgtt gttagtggaa tttgttgtat tgaagatgta aatgaaaaat
     1201 taagtataga tggtttaata aatagagcaa attttgcaca aaaaactgtt aagaataaac
     1261 caggtactaa ttatgctttt tataatgaca gtattcgtaa aaaaatgatt gaagaaaata
     1321 ctatcaagag tagaatacat gaagctattg aaaaaagaga atttatagtt tatttacagc
     1381 ctaaagttaa tttacatagt caaaaaataa attgtgcaga agctttagtt cgttggctta
     1441 ctccggataa aggtattata tctccagcaa tatttattcc agtacttgag aagaattttt
     1501 ttattgcctt agtagataag tatgtttttg aggaggtttg taaatggatt agaaagaggt
     1561 tagatgaaaa taaacctttt gttcagatat cagttaatgt ttcaagaata caattttata
     1621 acactaaatt tgtagaaact tattccaata tacaaaataa atacaggata cctaaaaata
     1681 ctatagaaat tgaatttaca gagagtgttg cttttgagaa tcaaaaacat cttttggaaa
     1741 ttatacatga tttgcatgaa aatggattta cttgttcttt agatgatttt ggaaaaggtt
     1801 attcgtcttt aagtgtttta aaagatttac catttgatgt tttaaagctt gattctatgt
     1861 ttttcaaggc tagtttagat aaagataaag agaaaatagt aataaaaaat attgtacata
     1921 tgttaaaaga acttaatatc acaactgttg ctgagggcat tgaatgcaag gaacaagttg
     1981 aatttcttag ggatattggg tgtgatttag ttcagggatt tgtattttat aaaccaatgc
     2041 caatattaga atttgaaaaa atattggata aagagtttgt ttataatagc taaaatgtac
     2101 tttataaaat atgaactaat taagtaaaat tattttgtac tgaataaatt tttactttat
     2161 ttacagaata atgattattt acagaaaagc gcgaaaagtg tattccttta agtgtgggat
     2221 ggatagcaca aatagaggag aaaaaatatt ggccatataa gaatgcataa taatataaat
     2281 atttgaaagg tcagcattat ataaaaatta aaaagaaaat aaataatttt tctataaaaa
     2341 agagactatg agaaaattta ctcatagtct cctaaataat gtatttattt tcttcctgca
     2401 acccatttta atccccaatg aaattcagta tccatttctc tatgaccttt gaagtattta
     2461 actacttttt caacactgaa tgtctcatca tttacatttt ctatcaatgc tattgaacac
     2521 atattatagc catttttatg ttcatcaagt ttgacaacta agtctgaatc ttgtttttgt
     2581 ttgattgtta caattccatc agcttcagac cagttagcta caccttcgta tataaaagca
     2641 taaataagta ttctttttat atcttttatt ttattaccat ttattcttaa attttctcct
     2701 tgtgtattac ttcctgttct gtcatctcca tctaattgag caaaaggtgg attgtctaaa
     2761 ctaccaaagg catttcctaa tgcttgaaca gcacctttta caccattttt catctcaaat
     2821 aggcaaccca aatctaaatc tatattactg cttcttaaag agccaaaaaa accctttttt
     2881 tgtacttttt gattccaatt taaattaact aagatttcac ctaaattgct attttccttt
     2941 tttgtaaggt ttattttttg tccctttttt aattctatag ccatagtaat cttcctccac
     3001 aaacatagat ttatttaaat ggtagcactt aataagtcaa tattcaacaa gattagaata
     3061 ataatattaa aattatacta aatatactaa aaagtaggaa tcacaatacc tttgtatttt
     3121 tcttcaatta agcttcttgc tttatctgat gtaagaacat cttgtagaac tttaatcttt
     3181 tcactgtctt tatcttcagt tctaaatgct aaaagatttg catactcgtc atttatagga
     3241 gctgtataaa ttccgttttt cttggcatca agaccagcag gtacagcata agtagtatct
     3301 ataaatgcag cagtcacatc tggaagagaa gatggaattt gagcaatatc taactctttg
     3361 aattgtattc cctttggatt ttctattatg tccttaggac taactaatcc atccccttta
     3421 ggtaacgtta aaagtccaat actttcaagg tatctaaggt tcttagaaca agaagatggg
     3481 ttattgctta ttgcaattgt atctcctttt ttaaattcat caacagattt tatcttataa
     3541 gagtaaagta ttgctgggca tacatatagt tttttaccag ccattatttt gtaacctttg
     3601 gccttaacag cttcttttag ataaggttca tgttgaaata gatttgcatc aatttcacca
     3661 ttatttaaag cttcgtttgg aagtatgtaa tcatcaaagt ttttaacttc taaagtatat
     3721 cctttttctt taataagtgg ttttaattct tctaataact ctcctcctgg aactaaagta
     3781 gcaccaacaa caattttttt atcatcttta gctttagaac atccaaccac agctaaagtt
     3841 agtactagac ataataacaa acataataat tttttgaatt tcatataaat tccctcctga
     3901 atataattga ttagttaaaa ataaaatacc attctttatc acactgcaaa ataaaaataa
     3961 gcctgagttt aaactcaggc tttaaaagct aatttagact catctttcag tataatactg
     4021 caggatttag caccaatgta tataaaaata tactggttgc tgggtttcat agggccagtc
     4081 ccttcaccac tctggataag aagtatcaat ttttaattat gttataaata ttatcatgat
     4141 tttttacgtc tgtaaacata attttataaa tattttaaaa tctttaatgt attttattta
     4201 acacctaaaa ttccagaaac tagaatatca gtatcagcac ctaagaaata gtcatttatt
     4261 tcaatagaat ccagagtatt tctcaaagca ttttcttcat gccttatacc aataagttta
     4321 ttttctacaa atgcaacatc acattttcca aaaaaatctc caaaaaattt tatactagtt
     4381 attatgcctt tatcaacatt taaattaaac tcaacatttc caccagaata ttttaattca
     4441 tttgaaagag tatattttgg tgaattacca aaattccaat cccaagtttc gtattttgat
     4501 ttagtaagct tttctatttg ttttatatca tgctcactca aacaataatt agtattatca
     4561 gtatttgttt tagaaagata atccattata gcatctttaa attctaatat gtccattttt
     4621 gaatgtaaat gttcacttat attggttaca cgagatttta cagattttat tccttttcct
     4681 tcaaatttta taggtttaac ctttaatgct tttgagaggt catttatttc agatgaaaat
     4741 aaaagagtcc catgatgcat tactttgttt ttgtagttgt attgagcatt tccagaaaat
     4801 ttcttgccat ctataagaag gtcatttctt ccagaaaatt cggcattgac atctagtgtt
     4861 ttaagtaaat ctattatggg ctgagtgaat cttctaaaat cactaaaatt attattgtta
     4921 caagctataa atgtaaaatt tatatttccc aaatcatgaa atacagctcc accaccagac
     4981 tgtctcctaa cgacaggtat agaatattct tttatatatt ctaaatttat ttcagaaagt
     5041 gtgttttggt tttttccaac aattatagaa ggttcattcc tccataaaat aaataagtct
     5101 tcatcaaaat tttttagaag atattcttcc attgctaaat taaaataagg gtttgttttt
     5161 tcattataaa ttaataacat taaagtagtt cctccataga attgataaaa tttttattat
     5221 gaatacaatt aattttataa ttcgacaata atataaaaac tcctttaaat tagaaatttt
     5281 aaaaactacc ttgcaaagtt taaataaata atatatactc aaaatatgtt taataaaagt
     5341 gaatagaagg gtagaggcgc aataatctat cagtactaat aaggagttaa gcacagagag
     5401 ttattaggaa aggagatatt gccgaagttt tataatcgat gctttaagat tatattgctg
     5461 ggggtacata gaaaatatgt acaactgtca caggtttatt tgtggtgagc tatcatttaa
     5521 ggaattatat tatatttatt tttactattg ttgatatatt gtaatgttta agccttgagt
     5581 gtttaccact caaggctttt ttagttttat tgtaacataa taccccgtac agttcacaaa
     5641 attaaaagga gagggagatt tatatgagga acaaaaaaat taatattatt tttctgacga
     5701 caatcatgtt cataatgtca acagtaatgg tttttgcaga agaagatata gacactattg
     5761 cactagccaa tgcagaaaaa tttgggattt taactttaat accaccatta gttgctataa
     5821 tactcgcatt tataactaaa aacgtaataa tttctttact tataggtatt ctttctggta
     5881 gttttataat taaagctagt ggtattaatg tttttgcgac atttatacag gcatttttag
     5941 atttagtaga cagagcttta gtatctttag cagacccttg gaatgcgggg ataatattac
     6001 aggttttggc aattggagga gtaataaatc ttgttgctaa aatgggagga gctaaagcta
     6061 tagctgaagc acttgctaaa agagcaaagt cagcaaaagg gacacagctt ataacatggt
     6121 ttttggggct tttagtattc tttgatgatt atgccaattc actaatagta ggtcctatga
     6181 tgagacctgt tgcagataaa atgaaaatat cgagagaaaa gctagcattt ataatagatg
     6241 ccacagcagc accagttgct ggtttagcta taatatctac atggataggt cttgaggttg
     6301 gtttaataca tgatgctttt gaaagtataa gtatagatgt agatgcattt ggtatatttt
     6361 taaatacaat accatttaga ttttacaata tattaatatt agctttcatt gtaatatcag
     6421 cattattatt aaaagaattt ggtccaatga gaaaagctga gataaaatct agaagtagaa
     6481 aaattagtat agaccttgat gaaggcgtag aagagttgga tgatttagct ccaaaaaatg
     6541 gagtaaaatt gagtgtatgg aatgctataa tcccaatagg aacattgata atagttgcat
     6601 tagcatcatt ttattatagt ggatatacat ctataatggg aggagacgat aaggctctga
     6661 tacaactatt tacaaattct ccatattctt ttgaagcaat aaaagaagca tttagtgcat
     6721 ctgatgcatc tagagcatta ttccagtctg cacttgttgc aagtttagtt gctattataa
     6781 tggctgtagt aaaaaagatt tttacaatat cagaagcaat tgatgtttgg atagatggaa
     6841 tgaaaagttt agtaatcact ggtgtaatat taatacttgc atggtcatta agttcagtaa
     6901 taaaagagtt aggtacagct aaatttttaa tacacctatt atcaggttca ctaccaccat
     6961 tcttattacc aagtttaata tttggtttag gagcaataat atcttttgct actggaacag
     7021 cttatggaac aatgggtata cttatgccac ttgcaattcc attagcatac tcattaaatc
     7081 ctgatatgtc ttatgtaata gtaagtacta gtgcagtttt aacaggtgca atatttggag
     7141 accattgttc tccaatttca gatacaacaa tactttcttc aatgggagct ggctgtaatc
     7201 atatagacca tgttaacact caaatgccat atgctatatt tacagcagta atcactattg
     7261 tatttggata tataccagct ggacttggat tgccaatata tatagtatta ccagtggcaa
     7321 tagctgctat atttgtaggt attcaaataa ttggtaagaa agttgatgaa gcggaaatag
     7381 aacttgtaga ataaagatat aaataagttt caccttttat tatcattatt ttgttagttt
     7441 ttagataatt ttaaaaagtt attgaaaata atggcgaaat atagtaaaat aaaagagtga
     7501 taagcggatg tggcggaatt ggcagacgca ctagacttag gatctagcgc cattggcgtg
     7561 ggggttcgac tcccttcatc cgcactttac agtacttaat tgtactgaaa aaaactgggg
     7621 ttgctggctt tcggagtggg ctatcccgtt tttatttttt tgtatatata atagattggc
     7681 actttagtac aaagtgcttt ttttataggc aaaaacagta catttatttc tgttttatta
     7741 tcattcatct attagaatat actttagtta agaatgtgtt aataagcagt gttcacattc
     7801 ttgataaaat gtggaataat atgtattttt actaagacgg aaatgaaata attaaaccat
     7861 taaataatat tataagatga tgaataagta gataaatcaa attttgtagg aggatattat
     7921 ggaaaaatat atatggttgt ttccattact ttttattttt catgatatgg aagagataat
     7981 aggttttgga atatggctta aaaaaaataa atcaatgctt gataagaagt atccatttat
     8041 cagtaaagtt tataaaaatt atagtactga aggcatggca tttgctgtgt ttgaagaatt
     8101 tattttatgc attattttct gtatacttac agttataaca gagaatcagt atgtatatct
     8161 actatggtta ggtagtttta tagcatatac cttacatttg gtaattcata tagggcagtc
     8221 aatcataata agaaaatata taccttcact tattaccagt atcatatgct taccaataag
     8281 catttggtgt ataagtaaga gtatttatat agttgattgt gaaatgagta caacaattct
     8341 gtacagtata attggcatta taattgtagc attgaattta aagtttgcac agtcgctgat
     8401 tggaaaattt acaaagtgga tgtcaaacat ataaatttta gtttattgga cagttcaagg
     8461 aatcagaaat tggaatttta tagtattaat attttatagt attaatataa tgtataaaat
     8521 tttatagcaa tgtatttcat aagtataaag tgactagaat tttaagaaat atacaaattc
     8581 tataaaaact aaataatttc aagtatattt taaaaatctt atttttcaca agtttaaaat
     8641 tgtaaacgat ttcatcaagt ctatgaatat acttttaaca tgttatagta aatctcaata
     8701 taaatttaca tttggttctt tgtgtgttat tttaataata aattaagtga aaatgttatt
     8761 ttacattaat atataatatc tttgcataag agtgaataat ataaaagaga aataattgat
     8821 aataaaaact taacaaaaaa attaatacat aaaaaaaaat aaatataatg tgttgacatt
     8881 taattgaaat attcatacaa taaaattgaa aataaatatt tccaaatgag attagcgaga
     8941 gagtccttta tacgaaaagg cgccgaagaa gaaatttaag aaatgccaat ttttagagaa
     9001 gctttcaggc aaaaatatcg ctaattgatg ggactctgga gagacttaag ttaagatact
     9061 ataagtcacc gaagaagcaa aataatatta aattattaaa tctttcaggt atacaaacag
     9121 ggatatatag gctaggatta ttttccatgc tgatatatct tttttttatg aaaaagtaca
     9181 ggaaataata tcaaagttac ttaaatacag taggtctaat tttctaggga gggttatata
     9241 tgaatgaatt gaaaagagta tctttgtaca atatacacaa agagcttgga gcaaaacttg
     9301 ttgaatttgc tggttgggaa atgcctttag aatatgaggg tataaataaa gagcatgaga
     9361 aggtcagaaa aagtgcaggt atatttgatg tatctcatat gggagaggta cagataaagg
     9421 gagcagagtc agaaaaattt atacaaaacc tagttacaaa tgatataagc acattaaaga
     9481 taaatgacat tatatataca cctatgtgtt atgaaaatgg tggagtagtt gatgatttat
     9541 taatatataa atttggtgaa gaagattatt tattagtaat aaatgcaggt aatatagata
     9601 aagatgtagc atggataata aaacaaagtg aaggatacaa tgtagatata aaaaatatat
     9661 ctagtgaagt gagtcaatta gcaattcaag gacctaaagc agaagaaatt cttcaaaaaa
     9721 tcacagatat agacttaaac tcaataaaat tttataagtc aattccatca acaaaagtat
     9781 gtggttgtcc ttgtttagtt tcaagaacag gatatactgg ggaagatggg tttgagatat
     9841 actgtaaaaa taaatatgta gaaataattt ggaatgaagt tctaaaggtt ggaggagaag
     9901 atatatgtcc agctggtcta ggttgtaggg atactttgag atttgaagca gctctacctc
     9961 tatatggaca tgaaataaat gaacacatat ctccaattga aggtggttta tctatctttg
    10021 tgaaaacaaa taaagaatca tttattggca aatcaatttt atcaaaagaa aaagaaagtg
    10081 gagctaaaag aaagttagta ggatttgaaa tgcaaggtaa aggaatgcct agaaatggat
    10141 atgatataag gattggtgat aaaacagttg gatttgtaac aacaggatgt gcatctccaa
    10201 cgacaggaaa aattttaggt atgggaatta tagattctga atatgcaaaa gtaggaaatg
    10261 aaataggtat agcaatcaga aaaaaagttg ttcctgctgt gatagttaag aaaccttttt
    10321 ataaaaaaca atataaaaaa gataatatta tattaaacaa agaaaataaa ttttcatata
    10381 tacctgctac aagtgaagat aaatcaaaaa tgttaaaagt agttggatta aattcagttg
    10441 atgaattatt ttcagatata ccagaagaag taaaattaaa aagagattta aatttggaaa
    10501 ttggaaaatc tgaattagag gtaagcaaaa tagtaaaaag attgtcagaa gaaaatttaa
    10561 gtttagaaga cttgacttgt tttcttggtg ctggtgcata tgaccattat ataccatcaa
    10621 ttataaaaca tataacttca agatctgaat tttatacagc atatactcca tatcaagctg
    10681 aaataagtca gggaacttta caagtagttt ttgaatttca atctatgatt gcagaaatta
    10741 caggtatgga aattgcaaat gcatcaatgt atgatggagc aactgctgca atagaagcat
    10801 gtataatggc aatgaatcag actagaaaaa gtaaaatagt agtgtcaaaa actattcatc
    10861 ctgaaactct gtcagtatta agaacttact tacaatataa agattgtgag atagtagaaa
    10921 ttgacttttg taatgaatat gggactacag atatagaaaa attaaaagct tctgtagaca
    10981 aagatacagc atgtgttctt atacaaactc ctaatttctt tggaattatt gaagaaatgg
    11041 aagaaataga aaagataact catgaaaata aggctatgtt aattatgagt gtagacccaa
    11101 tatcattagg agttttaaaa acaccaggtg agataggtgc agatattgtt gttggagaag
    11161 ctcaatcact tggaaaccct cttaattttg gaggtcctta tgtaggattt ttagctagca
    11221 aatctaaata tactagaaaa atgccaggaa gaatagttgg gcaaagttta gatgtagaag
    11281 gtaaaattgc atatgtatta actttacaaa ctagagaaca gcatgtaaga agagaaaaag
    11341 caacttctaa tatatgttca aatcaagctt taaatgctct tgtagcttca atatatatgg
    11401 ctactatggg taaagaagga tttaaagagg ttggtatgca gtctatgaaa aaagcacatt
    11461 atacctacaa taaacttgta caaactggaa aatataagcc aatatttaaa ggtaagtttt
    11521 tcaaagaatt tgctgtacaa ggaaatctta atatagaaac tataaatgat aaactcttag
    11581 aagaaaatat attaggaggt tataatttag aatacaatta tccagaatta aaaaattcaa
    11641 ctttgctttg tgtgactgag aaaagaagca aagaggaaat agataagtta gttggaataa
    11701 tggagggatt ataatgaaag aatacaatag tttgttgata gatatatcta aaaaaggtag
    11761 gaaagcatac tcacttccaa agttagatat agatgatata aaaatagaag atatgattga
    11821 cccagatatg gcaagacaaa gtgagttgaa tttgccagaa gttggtgaat tagaattagt
    11881 tagacattat acattattat caaataaaaa ctttggagtt gatacaggtt tttatccttt
    11941 gggttcttgt actatgaaat ataatcctaa aataaatgaa gatatggcag cacttccaaa
    12001 ctttactgga atgcatccat accaatcttc ggatacagct caaggttctc tttctttgat
    12061 gtatgattta tcaagaagac ttgcagaaat tacaggtatg gatgaagtta cactacaacc
    12121 ttcagcaggt tctcatggtg agtttacagg gcttatgatt ataaaagcat atcatgaaaa
    12181 tagaggtgac cataagagaa ccaaagtgat aattccagat tctgcacatg gaacaaatcc
    12241 agcaagtgca gctatggcaa actttgatgt gattcaaata gcatctgata aaaatggagc
    12301 tgtagacata aatgcattaa aagaggtttt gaatgatgaa gtagcagctc ttatgcttac
    12361 taatccaagt actcttggtt tatttgaaaa aaatataaaa gaaatagcta ctcttgtaca
    12421 tgaagcagga ggacttttgt actatgatgg tgcaaacatg aacgctatta tggggataac
    12481 aagacctgga gatatggggt ttgatgtggt tcatcttaat cttcataaga ctttttcaac
    12541 tcctcatgga ggtggaggtc caggagctgg tcctgttgga gttaaaaaag aattagtacc
    12601 ttttttacca ataccagtaa ttgaaagaaa agaagataag tatgtactaa attatgatag
    12661 agaaaaatct attgggaaaa ttaaaaattt ctatggtaat tttggagttc ttgtaagagc
    12721 ttacacatat atactaacta tgggaaggga tggacttaaa gaggctagtg aaatggcagt
    12781 tttaaatgct aattatataa aggaaagtat aaaagatgat tatattttgc caatagatac
    12841 cttgtgtaag catgagtttg tattaggtgg attgccaaga ggagaggcca atataaaaac
    12901 tatcgatatt gcaaaaagac tactagatta tggataccat cctccaacaa tgtactttcc
    12961 tcttattata aatgaggcac ttatgataga acctacagaa agtgagagta tagagacatt
    13021 agatagtttt atagaagcta tgaaaagtgt tgctaaagag gcaaaggaag aaccagaact
    13081 attgaaaact gctccacata atactttggt caaaagagta gatgatgcaa gggcagtaaa
    13141 gaaacctata ctaacatggt cacaaagata aatagttaaa aagtagagat ttaaagtata
    13201 aagagaatta aatttgtaag aaaaagctat ctaacttaat ctagtttaga tagctttttt
    13261 gtatattagt atgtatggta ttttctatat aaagttttaa attgtattag tgcttatata
    13321 gaatattgat atgatgatta tgtatagata ttaataagaa ttgttgaatt tatcttgcct
    13381 taactttatt tactctttta tattaagaaa aacttaacta aaatatagcg aaattcataa
    13441 aaatttagga aatcttaaga attataata
//
LOCUS       DAMJXI010000090        13142 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.095, whole genome shotgun sequence.
ACCESSION   DAMJXI010000090 DAMJXI010000000
VERSION     DAMJXI010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13142
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.095"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            218..1099
                     /locus_tag="PC465_003307"
     CDS             218..1099
                     /locus_tag="PC465_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2650586.1"
                     /translation="MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELG
                     VALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGT
                     DFIPDIVHKFLKSNPAKSIDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIP
                     VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIAFNQRSGLRYIIDDMFKKINQQPNI
                     VYEVEEDQVIAGLVAKNFGIAVVPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYL
                     PPAIKNFKNFVIKNAQL"
     gene            complement(1307..2170)
                     /locus_tag="PC465_003308"
     CDS             complement(1307..2170)
                     /locus_tag="PC465_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HDF2650587.1"
                     /translation="MLSSYVKRVSKIIKKKYIMFIDESGRADINHEDPFTLTGVIFEY
                     KYAVSQGDYVCSLRKEMDAFKEYCFGTSNIGIHLTDISRKSRAFEKFDDSQIKLFYDE
                     LPLFLSRLECTIISVTVDKARLKKYYAPSKEPYVVAFIHVLQNFYSFVNNETVESARI
                     VIESRDDVSNLKVQKAFFDVFNNGTIYLDIDEELRDKVKGFIIAKKEDADYREGLEIA
                     DILCNPLSRARRGLIEANPKCMQYGEKNKIFKSVRNKIYTPTSVNDIRNWGFKEVPIV
                     EPVGPWLEKMR"
     gene            complement(2325..4259)
                     /locus_tag="PC465_003309"
     CDS             complement(2325..4259)
                     /locus_tag="PC465_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp22"
                     /protein_id="HDF2650588.1"
                     /translation="MKKSLKKYLVLALTLVLVFACGVPESSAASKHVIIVNSRKNTLG
                     YFVNNKLVKEFRVATGKKGSETPTGKTKVVNKIKNRPYYKGNIPGGSPRNPLGDRWMG
                     LALKGTYGDTYGIHGNNNESSIGKHISGGCIRMHNKDVRWLFDQVPVGSDVIIDYSND
                     SYVKIAAKYKINLNQTGWKTENGKKYYVKSDGTYQKNSWLKVNGKMYYFDASGVMQTG
                     WKTINNKKYYLGTDGARVSGWKVIDGKTYYFNSDGVMQTGWQEKNGKKYYLGSDGLAV
                     TGWQEIDGNKYYFDKTGIMQTGWQQIDGKSYYLDKDGKMLTGSQKIDGKDYTFNEDGT
                     INPTWDTIIGANRFDTAKKISSVGNWNADSSDTVILVNGNAIADGITATPLASSYDST
                     ILLTNTANLPTETVEEMKLLAPKTVILIGGENAISSKLEQEIKTTFNTETKRIAGQDR
                     YQTATRIAEELGNREEIKTAYMVSGNGEADALSVASKAGEEKQPIILVNKDGITEESY
                     KWLTERKLENAYFIGGPSAINDSVIAKMNDITTEDISGNRIYGDSRVDTNAKVIEKFY
                     GDTDLQAVLVSKSDALVDALSAGPLAVKLHSPIVLMDNSGLSSEQQRVFANKKVETPY
                     QIGGGVSYIVMDKLMDILAK"
     gene            complement(4371..5384)
                     /gene="galE"
                     /locus_tag="PC465_003310"
     CDS             complement(4371..5384)
                     /gene="galE"
                     /locus_tag="PC465_003310"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HDF2650589.1"
                     /translation="MAVLVAGGAGYIGSHTAIELLESGYEVVIVDNLSNSNSIVVDRI
                     KELSKKPVKFYNIDIRNKDEMHVVFKENNIESIIHFAALKAVGESVEKPIEYYSNNLI
                     STLNLFELMREYGVKKFVFSSSATVYGDPHTCPILEDFPLSVTNPYGRTKLMIEQMLV
                     DISKADKSLDIALLRYFNPVGAHKSGRIGEEPNGVPSNLMPYITKIAVGKLKELSVYG
                     NDYPTHDGTGVRDYIHVLDLAAGHVKALQKLEENPGLVVYNLGTGKGYSVLDLVKAFS
                     KASGKEIPYKIVGRRAGDVAMCYADSSKAEKELGWKAKYELEEMCEDSWRWQSMNPNG
                     YEE"
     gene            complement(5408..6277)
                     /gene="galU"
                     /locus_tag="PC465_003311"
     CDS             complement(5408..6277)
                     /gene="galU"
                     /locus_tag="PC465_003311"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDF2650590.1"
                     /translation="MTVKKAIIPAAGLGTRFLPATKSQPKEMLPIVDKPTLQYIIEEA
                     IESGIEEILIITGRNKKSIEDHFDKSVELELELEQKGKTEMLEMVRDISNMVNIHYIR
                     QKEPKGLGHAIYCAKSFIGDEPFAVLLGDDIVDSDVPCLKQLIDTYNEYKTTVLGVQK
                     IAKEDTNKYGILDVKHIEDRVYKVKDMVEKPAIEEAPSDIAILGRYIITPAIFSILEK
                     QTPGKGGEIQLTDALQTLGKQEAIYAYNFEGRRYDVGDKIGFLEATIDFALKRENLKD
                     DLMDYMRKKVSEK"
     gene            complement(6475..6795)
                     /locus_tag="PC465_003312"
     CDS             complement(6475..6795)
                     /locus_tag="PC465_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650591.1"
                     /translation="MSSKYNVWTFNYEFLGLDSGDEKNNEVYYEIDLDEILNENYIDE
                     DIDSGLDSDGNSILGELISEMDIDEDVSVDMTYQELEVDLEDLDSYLDEDIDSDIKGI
                     LDEI"
     gene            complement(6785..8776)
                     /locus_tag="PC465_003313"
     CDS             complement(6785..8776)
                     /locus_tag="PC465_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650592.1"
                     /translation="MLKLGEKIIYELSDGFELSGISRYSKEYKKLHITNLGNIIISKS
                     DEVNEDTGVKYIYSFSDNKEKLEAVLEDSQIIVYGNNLPFYIKSENSSKNVTANLTMK
                     ITLDEYDLICKSQREFIFYLKDNMTILSLDDNKFYMGGINKDNEKFIFISGKNRFEIN
                     FDDIERYILEDKRVSLKGYFHMEREGIIVRSVSIFNNNIDSVVPSDLNERVKDNQKIG
                     NLPKDCEIVFCKISGNIDGFDYKNTNMLLVKYQDQLIFINKKSKKTIVKSAKDNCSKL
                     NLGEDIILYDNKNVFNLHINDKNREIMQIDDLKDIENEIVGYTLKHAPFFIQEDFDSL
                     TILKSFQKEIISIKNSDIKDIVINKELENENSNFVETEIKFNNQKVLLNLSKSMVQKL
                     MQDVFIYAKQPLLKENSIEVIYKNWSKAMNDMIIFNFFGNIYYMKSEFDKILEKELND
                     EIRIEVINSLYKQIQEQRNNLDLLSAYMPRILENQEIDLFEKYNTKLDVQVFKQIKNL
                     LSDLSYNISSYLNEVEKSLDNIIFVISGEDKKKYNYRMLKESESASLDVFLKQAISRL
                     NHLVENMYPYYVDETSREMFKLFELLWKNYRNIDDDSIKEILFERITNTYVFKQLTLN
                     NSTKERRKDIIEKIYNSVDYGTNKLDENMFFTGGIKYVK"
     gene            complement(8899..11442)
                     /locus_tag="PC465_003314"
     CDS             complement(8899..11442)
                     /locus_tag="PC465_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HDF2650593.1"
                     /translation="MKVLSENNIIRNTVLNVTASFLKQESKINEKLDGVLEKKFEKVE
                     FNEAKYAELLKFNILFYKTLARNTEPLIGKWIVDKYIPEIDELEKDLELTTAKCRKYV
                     NKAMKEGLDSLKANDLNSFLAYDKMELSERRRRLEKDYKVLNLYKDLLNISLRKISLE
                     KKECGDLFLKNQADAKRELKREIIFCVNKILASNKDVVPNNVEENNEQDKVEIKATEI
                     EDLQLGKDNSENDMLLNEIKNSKVKHESKSNDIESKFIDKLNSLNNESVSQTIHNEYK
                     KLCGLEELHSVEGYGFGKEIIKDFACATVVLEFLKRRNRDLIEGAMRLTIIGEFGPEN
                     FKEFVDYVIKNKTEISEDTWNKAQNLIKDNYSELENHEIASKRTRRNKDIDIEEYIYM
                     IKNADKDICFRSSISIEDDAEEGVKEEIDSNNQDIGDVVEDKDTTDKEYDSNKEDIIE
                     PENKKSKKKAKLFGFIKKDNEEVEQEEENLNDISPDIILDKPVENHQVKSEEMEQNEL
                     KEIKQKEPSQHIEEERNVKIEKPINNNLDEKVSSNNESKLEKESKNLEDKKAKEIKEE
                     KLENEKSVVIPIKKKENSNKKSKNSSKDKYRENKKEMKNYVSDKEDSLDDEEVVSKKS
                     RLKETIIAVVIVVIVGVGYFITVGNNKKNDKENIPKSSTQQQANNKLTEEEKKAQAEK
                     EKKEAEEKAKAEKEAQEKAQAEKKAKEMEAYKDGKGVYYTVYAGSLKVEKTAKETAKE
                     YEAKGISSTIIQENGYYKIKIGDYSQYGEAQEKCNELAKKSIDTYIAMYDKYYDYKLE
                     ELKESAPSLSAEELKQKYEDLRSELKNKSGYREYVKHLDKLYEEIVEGA"
     gene            complement(11720..12054)
                     /gene="rnpB"
                     /locus_tag="PC465_003315"
     ncRNA           complement(11720..12054)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="PC465_003315"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            12186..12863
                     /gene="srtB"
                     /locus_tag="PC465_003316"
     CDS             12186..12863
                     /gene="srtB"
                     /locus_tag="PC465_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtB"
                     /protein_id="HDF2650594.1"
                     /translation="MKKLYRIVINIILVLVILYSGFNIYSKLTKYNHDTKISSELQKK
                     EYKKEDLSKINSDFKFWLSVENTNINYPVVQSKDNSYYLDKDFYKKDSISGTLFMDYR
                     NKSIDDKNIIIYGHNMKNKTMFNNLNKFKDADFFKKNNKIKITLNGKEFLYDVFSAYI
                     VESDYDYLKTNFNNESDYQNYINDITSKSLYKSPIKVNSNDKIVTLSTCTYEFDDARM
                     VIHGRLI"
     gene            complement(13023..13097)
                     /locus_tag="PC465_003317"
     tRNA            complement(13023..13097)
                     /locus_tag="PC465_003317"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13063..13065),aa:Thr,seq:tgt)
BASE COUNT         4056 a         2295 c         1337 g         5454 t
ORIGIN      
        1 agattttgtt tatagatttt atttataaga taattcttgt atttttctat taggtcgtat
       61 aaatatattt atcttataat tcagacaaaa aacgataaat ttttttaaaa gcttttattc
      121 ttactatata atcatatata ataaaaatgt aaaaatatct taaaggttaa cttctacaaa
      181 tatataaata aaatacctat gaaaggatga acaaaaattg aatttatatc acttacgcta
      241 ttttgttaca ttggcacatt tagaacacta tacaaaagcg gcagaaaatt tatctataac
      301 acaaccaagc ttaagtcatg ctatttcttt actagaaaat gaacttgggg tggctttatt
      361 tgaaaaagaa ggtagaaata tagtccttac taagtatgga aaaatatttt taaaagatgt
      421 ggaaaaatca ttagaaattt tagattcaag tgtaaaatca ttaaaaataa ctggtactgg
      481 tgaaggacaa atagacttag cttttcttag aacacttggt actgatttta tcccagacat
      541 agtgcacaaa tttttaaaat ctaatcctgc taaatcaata gattttaaat ttcatactgg
      601 tgtaactact gacattattc aaggtcttaa agaaagaaaa tatgatattg cattttgttc
      661 gaaacttgaa aaagaaaagg gaattgaatt tatacctgtt gccaaacaag atttagtact
      721 aattgtacca tatagtcatc cactagctgc aaaggatact atagatttaa aagaaaccat
      781 accttatcct caaatagcat ttaatcagag aagcggtctt agatatataa ttgatgatat
      841 gtttaaaaaa ataaatcaac agcctaatat agtctatgaa gtagaggaag accaagtaat
      901 tgctggatta gttgcaaaaa atttcggaat tgctgtagtc ccaaatatga atatgcttag
      961 ctttacaaaa gtaaaagtaa ttcagattat tcacccaagt tgggaaagaa acttttactt
     1021 agcatttata aaagatagat atttgcctcc tgcaattaaa aactttaaaa actttgtcat
     1081 taaaaacgct caattataat ttattaataa aggggttatt tttaaatatc ctcttttatt
     1141 ctttttataa aataaaaaaa tctatacttt taaaagtata gattcctaac tgacagtcgg
     1201 catccgagtc tcagtaatta tcgttatata acagcaactg gattcagttc ctgaataact
     1261 aggttactta cattatatca gattttttaa aatttgtcaa ttgtatctaa cgcatttttt
     1321 caagccatgg tccaacaggc tctacaatag gaacttcttt aaatccccaa tttcttatat
     1381 cattcacact cgttggagta tatattttgt ttctgacaga tttgaatatt ttgttttttt
     1441 ctccatattg catacacttt ggattagctt ctattaaccc tcttcttgct ctgctaagag
     1501 gattacataa aatatctgct atttctaaac cttctctata gtcagcatct tcttttttgg
     1561 caattataaa acccttaacc ttatctctta attcttcatc tatatctaag tatattgttc
     1621 cattattaaa tacatcaaaa aacgcctttt gtacttttaa gtttgagaca tcatcccttg
     1681 actctataac tattcgtgca gattctacag tttcattatt tacaaatgaa taaaaattct
     1741 gaagaacatg tataaaagcc acaacatacg gttcctttga aggtgcataa tatttcttta
     1801 atctagcttt atctactgtt actgatatta tagtacactc taatctagat agaaataaag
     1861 gcaactcatc atagaataac ttaatctgtg aatcatcaaa cttctcaaat gctcttgatt
     1921 ttcttgatat atctgtcaaa tgtattccta tgttactggt tccaaaacaa tactctttaa
     1981 atgcatccat ttctttcctc aaagaacata cataatcgcc ttgacttact gcatatttat
     2041 attcaaaaat tactcctgtc aatgtaaatg ggtcttcatg atttatatca gctcttccac
     2101 tttcatcaat aaacattata tattttttct ttataatctt actcaccctc ttaacatatg
     2161 atgatagcat ctatattcat tttatatgag ttttaaaaat attccaagat ttttatataa
     2221 cttaaactta attttatact aaaaaattga gatgtaaaac aatcaagctt ttattgattg
     2281 aatttcacat ctcaattata attatttttc aatatatatt tttactattt tgcaagaata
     2341 tccattaatt tatccattac tatataagat actccgcctc ctatttgata aggagtttca
     2401 acttttttat ttgcaaatac tctttgttgc tctgatgata atcctgaatt atccattaaa
     2461 actattggtg aatgtaattt tacagctaat ggtccagctg ataaagcatc tactaaagca
     2521 tctgatttac taactaatac agcctgtaaa tcagtatctc catagaattt ttctattact
     2581 ttggcattag tatctactct actatctcca tatattctat ttcctgaaat atcttcagta
     2641 gttatatcat tcatttttgc tattactgaa tcgttaattg cacttggtcc acctataaag
     2701 tatgcatttt ctaattttct ttctgttagc catttataag attcttctgt aattccatct
     2761 ttattgacta atattatagg ttgtttttct tccccagctt tagaagctac agataaagca
     2821 tctgcctccc catttccaga aaccatatat gcagttttta tttcttctcg atttccaagt
     2881 tcttcagcta ttcttgtagc agtttgatat ctatcttgac ctgctattct ctttgtttct
     2941 gtgttgaaag tagtttttat ttcttgctct aatttagaac ttattgcatt ttctccacct
     3001 atcaagatta ctgttttagg tgctaataac ttcatttctt caacagtttc agttggtaaa
     3061 ttagctgtat tagtaagtag tattgttgag tcatagctac ttgctaaagg agttgctgtt
     3121 ataccatcag ctattgcatt accatttact aatattacag tatctgagct atcagcattc
     3181 cagtttccaa ctgaacttat ctttttagct gtatcaaatc tatttgcacc tataattgta
     3241 tcccatgtag gatttatagt tccatcttca ttaaaagtat aatctttccc atctattttt
     3301 tgagaaccag ttagcatctt tccatctttg tctaaatagt aagacttacc atctatttgt
     3361 tgccatcctg tctgcattat tcctgttttg tcaaagtaat acttattacc atctatttct
     3421 tgccatcctg ttactgctaa accatcagat cctagatagt atttctttcc attcttttct
     3481 tgccatcctg tttgcattac tccatctgag ttaaagtaat aagtttttcc gtctattact
     3541 ttccatccag atactcttgc tccatcagtt cctaaataat attttttgtt attaattgtt
     3601 ttccatcctg tttgcattac tcctgaagca tcaaagtaat acatttttcc atttactttt
     3661 agccaactat tcttttggta tgttccatca gattttacat aatacttctt accattttct
     3721 gttttccatc ctgtttgatt tagatttatc ttatattttg ccgctatctt tacatagctg
     3781 tcgttactat aatctataat tacatctgaa cctacaggaa cttggtcaaa taaccatcta
     3841 acatctttat tgtgcattct tatacatcca ccagaaatat gctttcctat agaactctca
     3901 ttattatttc catgtattcc atatgtatct ccataagttc cttttaatgc taatcccatc
     3961 catctatctc ctaatggatt tcttggactt cctccaggta tattaccttt ataatatggt
     4021 ctatttttta tcttgttaac tacttttgtt ttccctgttg gtgtttctga ccccttttta
     4081 cctgttgcaa ctctaaattc ttttacaagt ttattattta caaaatatcc tagagtattt
     4141 tttcttgaat ttactataat cacatgttta ctggctgcgc ttgattctgg tacgccacat
     4201 gcaaatacta aaactaaagt cagtgctagt actaaatact tttttagact ttttttcact
     4261 ataacttccc cctcttttag aaacattact acatgtgtct aattataaca taaaattacc
     4321 aataccttat atttacaaat ttgttacatt tatacatata agtatgtatt ctactcttca
     4381 tacccattag gattcatact ttgccatctc catgaatctt cacacatctc ttcaagttca
     4441 tacttagctt tccatccaag ctctttttct gcctttgaag aatctgcata acacatggct
     4501 acatctccag cccttcttcc tacaatctta tatggtattt cttttccact tgctttagaa
     4561 aatgctttta ctaaatcaag aacactatac ccctttccag ttcctaaatt ataaacaaca
     4621 agtcctggat tttcttctaa tttttgtaat gcttttacat gaccagcagc taaatctaat
     4681 acatgtatat agtctctaac tccagttcca tcatgtgttg gatagtcatt accataaaca
     4741 ctcaattcct tcaatttacc tactgctatt tttgttatat aaggcattag attgctcgga
     4801 actccatttg gttcttcacc tattctacca cttttatgag caccgactgg attaaagtat
     4861 cttaaaagag ctatatccaa tgacttatct gcttttgata tatctactaa catctgctct
     4921 atcataagtt tagttcttcc atatggattg gttacagaaa gtgggaaatc ctctaatata
     4981 ggacaagtat gtgggtctcc atatacagta gctgaagaac taaatacaaa ctttttaaca
     5041 ccatattctc tcattaattc aaataaattt aaggtactta ttagattatt gctgtaatat
     5101 tcaattggtt tttctactga ttcaccaact gcttttaaag ctgcaaagtg tataattgat
     5161 tcaatattat tttctttaaa tacaacatgc atttcatctt tatttctgat atcaatatta
     5221 taaaatttta ctggtttttt agataattcc ttgattctat caaccactat tgagttgcta
     5281 ttacttaagt tatcaactat aacaacttca taacctgatt ctaaaagttc tattgctgta
     5341 tggcttccta tatatcctgc tcctccagct actaaaactg ccattgtaat tacctctttt
     5401 ctaatattta tttttcactt actttttttc tcatatagtc cattaaatca tcttttaaat
     5461 tttctctctt tagagcaaag tctattgttg cctctaaaaa accaatctta tctcccacat
     5521 catatcttct accttcaaag ttataagcat aaatagcctc ttgttttcca agagtttgaa
     5581 gtgcatctgt cagttgtatc tctccacctt taccaggtgt ctgtttctct aatatgctaa
     5641 atattgcagg agttattata tatcttccaa gtatagctat atcagatgga gcttcttcaa
     5701 ttgcaggttt ttcaaccata tctttaactt tatatactct atcttcgata tgttttacat
     5761 ccaatatacc atatttatta gtatcttctt tagctatctt ttgaacacct aatacagttg
     5821 ttttatactc attataagta tctattaatt gttttaaaca cggaacatct gaatctacta
     5881 tatcatcacc taataatacg gcaaaaggtt catcacctat aaaacttttt gcacagtaaa
     5941 ttgcatgtcc aagacctttt ggctcttttt gtcttatata atgaatattt accatatttg
     6001 atatgtctct taccatttct aacatctctg tcttaccttt ttgctctagt tctaactcta
     6061 attcaactga tttatcaaaa tgatcttcta tagatttttt atttctacct gttattataa
     6121 gaatttcttc aattcccgat tctatagctt cttctattat atactgtaaa gttggtttat
     6181 ctactatagg aagcatttct ttgggctgtg attttgttgc tggtaaaaat ctagttccta
     6241 gccctgctgc tggtattatt gcttttttaa ctgtcatctg cattttttca cccttcttcg
     6301 taaattttct attgtaccaa attaatatac catatttata ctttttcttc aaactctata
     6361 ttatcccaat atttaatgct ataagataat ataaggtaga tgaaatttca tctaccttta
     6421 gttttataag ttaatattgt attgtttata ttttatccaa aacttataca ggtactaaat
     6481 ttcatctaag atgcctttta tatcactatc tatatcttca tctagataag aatctaaatc
     6541 ttctaagtca acttctagtt cttgatatgt catatcaaca ctgacatcct catctatatc
     6601 catttctgat attaattctc ctaaaatact atttccatca gaatctaaac cactatctat
     6661 atcttcatct atatagtttt catttaaaat ttcatctaaa tcaatctcat aataaacttc
     6721 attatttttt tcatcccctg agtccaatcc taagaactca tagttaaaag tccaaacatt
     6781 gtatttactt gacatacttt attcctcctg tgaaaaacat attttcatct agtttattgg
     6841 ttccataatc aacagagtta tatatttttt caattatgtc ttttcttctt tcttttgtac
     6901 tattatttaa tgtcaattgt ttaaatacat atgtatttgt tattctctcg aataatattt
     6961 cttttatact atcatcatca atatttctat agtttttcca caataactca aataacttaa
     7021 acatttccct actagtttca tctacataat aaggatacat attttctact aaatggttta
     7081 atcttgatat ggcttgtttt aaaaatacat caagacttgc actttcactt tcttttaaca
     7141 ttctataatt gtatttcttc ttatcttctc ctgaaattac aaagatgata ttgtctaaac
     7201 ttttttcaac ttcatttaaa taactgctta tattatatga taaatcagac aatagatttt
     7261 taatctgctt aaacacttgt acatcaagtt tagtattata cttttcaaac aaatctattt
     7321 cttgattttc taatattctt ggcatatatg ctgacaataa atctaaattg tttctttgtt
     7381 cttgtatttg cttataaagt gaatttataa cttctattct tatttcatca tttaactctt
     7441 tttctaaaat cttatcaaat tcagatttca tatagtaaat atttccaaag aaattaaata
     7501 ttatcatatc attcatagct ttagaccaat tcttatatat cacttcaata gaattttctt
     7561 taagtagagg ttgctttgca tatataaata catcttgcat aagtttttga accatacttt
     7621 tacttaagtt taaaagtact ttttgattat taaattttat ttccgtttct acaaaattag
     7681 aattttcgtt ttcaagttct ttattaatta caatgtcttt tatatcacta ttttttatag
     7741 atatgatttc tttttgaaaa gactttagaa tagtcaagct atcgaaatct tcttgaataa
     7801 aaaatggagc atgttttaat gtatatccca ctatttcatt ttctatatct tttaggtcat
     7861 ctatttgcat aatttctcta tttttatcat ttatatgtag gttaaataca tttttattat
     7921 catataatat tatatcttct cctaaattta acttagaaca attatctttc gctgacttta
     7981 caatagtctt cttagatttc ttatttataa aaattaattg gtcttgatat tttactaaaa
     8041 gcatgtttgt gtttttataa tcaaatccat ctatatttcc tgatatcttg cagaatacta
     8101 tttcacaatc tttaggaaga tttcctattt tttggttatc tttaactctc tcatttaaat
     8161 cagatgggac tacactatct atattgttat taaatataga tacagacctt actataatcc
     8221 cctctctttc catatgaaag tatcccttca atgacactct tttatcttct aaaatgtatc
     8281 tttctatatc atcaaaattt atttcaaatc tatttttccc actgataaat ataaacttct
     8341 cattatcttt attaattcca cccatataaa acttattgtc atctaaactt aatatagtca
     8401 tattatcctt tagatagaat ataaattctc tttgactttt gcagattaaa tcatattcat
     8461 ccaaagttat tttcatagtc aaatttgctg taacattttt acttgaattt tcacttttta
     8521 tgtaaaaagg caagttattt ccatagacaa ttatttgaga atcttctaaa actgcctcta
     8581 atttttcttt attgtctgaa aaactatata tatattttac acctgtatcc tcattaactt
     8641 catctgattt gctgattatt atattcccta gatttgttat atgaagcttt ttatattctt
     8701 ttgagtatct acttatgcca ctaagctcaa acccatctga aagctcatat atgatttttt
     8761 ctcctaattt caacatacct tcaccaccta aacagaatta taagtatttt ataaaggtga
     8821 ataaaatgtc tcaaaacaaa taatattttt tttaatactt tttattctga gacatagttt
     8881 ctcctttttt ataatgctct aagcaccttc aactatttct tcataaagtt tatctaaatg
     8941 tttaacatat tcacgatatc cagatttgtt ctttaactca cttcttaaat cttcatattt
     9001 ttgtttaagt tcttcagcac tcaaagaagg agctgattct tttaattctt ctaacttata
     9061 atcatagtac ttatcataca tagctatata tgtatcaata gacttcttag ctagttcatt
     9121 acatttttct tgtgcttctc catattgaga ataatcacct atttttattt tatagtatcc
     9181 attttcttga attattgttg aagaaatacc tttagcctca tattcttttg ctgtttcttt
     9241 tgctgttttt tcaactttaa gtgaacctgc ataaacagtg taatatacac ctttaccatc
     9301 tttatatgct tccatttctt ttgctttctt ttcagcttgt gctttttctt gagcctcttt
     9361 ttcagctttt gccttttctt ctgcttcttt tttctctttt tcagcttgtg cttttttctc
     9421 ttcttcagtt aatttattgt tagcttgttg ttgagttgat gactttggaa tattctcttt
     9481 atcatttttc ttattgttgc ctactgttat aaaatatcct acaccaacaa taaccactat
     9541 aactactgct ataatagttt cttttaatct actcttctta gaaacaacct cttcatcatc
     9601 taaagaatct tctttatctg atacataatt tttcatttct ttcttgtttt ctctatattt
     9661 gtccttagaa gaatttttag attttttatt actattttct ttctttttaa taggtattac
     9721 tactgatttt tcattttcta atttttcttc ttttatctct tttgcttttt tatcttctaa
     9781 gtttttactt tctttttcaa gcttcgattc attatttgaa gatacttttt catctaagtt
     9841 attatttatt ggtttttcta tttttacatt acgttcttct tctatatgtt gacttggttc
     9901 tttttgtttt atttctttta attcattttg ctccatttct tctgatttta cttgatgatt
     9961 ttcaactggt ttatctaaaa ttatatcagg agaaatatca tttaaattct cttcttcttg
    10021 ttcaacttct tcattgtctt ttttaataaa tccaaataat ttagccttct ttttactctt
    10081 tttattttct ggttcaatta tatcttcttt attgctgtcg tactctttat ctgtagtatc
    10141 tttatcttct acaacgtcac ctatatcttg attattacta tctatttctt ctttaacccc
    10201 ttcttcagca tcatcttcta ttgaaatact acttctaaag caaatatctt tatctgcatt
    10261 ttttatcata taaatgtatt cttcaatatc gatatcttta tttcttctag ttctttttga
    10321 tgcaatttca tgattttcta attcactata gttatctttt attagattct gtgctttatt
    10381 ccatgtatct tcactaattt ctgttttatt tttaattaca tagtccacaa attccttaaa
    10441 attttcagga ccaaattctc caattatagt cagtctcatt gcaccttcta taaggtctct
    10501 atttcttctc tttaaaaatt ctaatacaac cgttgcacaa gcaaaatctt taataatttc
    10561 tttgccaaaa ccatatcctt caacagaatg aagttcttct aatccacata acttcttata
    10621 ttcattgtgt attgtttgag atacactttc attatttaag ctatttaact tatctataaa
    10681 cttcgattct atatcatttg attttgattc atgttttact tttgaatttt taatttcatt
    10741 tagtagcatg tcattttctg aattatcttt acctaattgc aaatcctcaa tttcagttgc
    10801 ttttatttct actttgtctt gttcgttatt ctcttccaca ttattaggta ccacatcttt
    10861 attgctagct aatattttgt ttacacagaa tataatttct ctttttaatt ctcttttcgc
    10921 atctgcttga tttttaagaa ataaatctcc acattctttc ttttctaaac ttatttttct
    10981 aagagatata ttaagaaggt ctttatatag gtttaaaacc ttataatcct tttctaaacg
    11041 tcttcttctc tctgatagtt ccattttatc ataagctaaa aaactattta aatcattggc
    11101 ttttagagag tctaatccct ctttcatagc cttatttaca tactttctac attttgctgt
    11161 agttaattct aaatcttttt ctaattcatc tatttcaggt atgtacttat ctactatcca
    11221 tttgccaata agtggttctg tatttcttgc taatgtctta taaaacaata tattaaattt
    11281 taaaagctct gcatattttg cttcattaaa ttctactttt tcaaatttct tttccaaaac
    11341 accatctagc ttttcattta ttttagactc ttgttttaaa aaacttgctg tgacatttaa
    11401 aacagtgttt cttattatat tattttcact caaaaccttc actccttaaa tcaattattt
    11461 tattgtaata tttacattgt gcaaagttgc taatttgatt atgatatcta aataattatt
    11521 tactaaattt gctacatctt atatcatatc atattattta catcatttta ctttttcttt
    11581 ttatatctat cttatattat accattttta atatctgtac taacttatat tacaatattc
    11641 ctcaaaattt taaaagtaga ttagacaaat ttacaaataa aaaaacatca gtttaaactg
    11701 atgtttttga ctatcgaaat aattaagcaa gtctataagc ggagttctgt attagataat
    11761 catctttcta ggcctattgt caccaatagg ctcaagcgac ctacctaccg gagagtacga
    11821 gcagcactct ttattcctat cttggtcttg ctccaggtgg ggtttacata gccaactagt
    11881 cgcctagctg ctggtgagct cttacctcgc ctttccatcc ttaccacaat agtggcggtt
    11941 tatttctgtt gcactatcct taggatcgct cccactaggc gttacctagc accctgctct
    12001 atggagctcc gactttcctc atgtaagatt acatgcgatt atctggctta cttaatattt
    12061 attttactta gttatgttaa cacaaattct tttacatgtc aaagtaatat tatactaaaa
    12121 atttaaattt attcaaaaat agtgtaatat agatatataa actacattta actcgaggtg
    12181 atatattgaa aaaattatat agaatagtaa ttaacattat actagtatta gtaatacttt
    12241 acagtggatt taatatatac tcaaaactta ccaaatacaa tcatgatact aaaatatcct
    12301 cagaacttca aaaaaaagaa tataaaaaag aggatttatc aaagattaac agtgatttta
    12361 aattttggct ttctgttgag aatacaaata taaattatcc agttgtacaa tctaaagata
    12421 attcttacta tcttgacaaa gatttttata aaaaagattc tatttctggt acactgttta
    12481 tggattatag aaataaatct attgatgaca aaaatatcat aatatatgga cataatatga
    12541 aaaataaaac tatgttcaac aacctaaata agtttaaaga tgctgacttc tttaaaaaaa
    12601 ataataaaat aaaaataacc ttgaatggaa aagaattttt atatgatgtt ttttctgctt
    12661 atattgtaga atctgattat gattatctaa aaacaaattt taacaatgaa tctgattatc
    12721 aaaattacat aaatgatatt acttctaaat cattgtataa atctcctatt aaggtaaata
    12781 gcaatgataa aatagttaca ctttctacat gtacatatga atttgatgat gccagaatgg
    12841 tgattcatgg tagattgatt taaaactcac agacacagtt taaaacaata attttaaact
    12901 gtgtcatctt ttatacctat aatttataaa ttagaccact aaaagtattt aatacaaaat
    12961 aacaaataca tcaaacaata aaaaacaata aaaaaagact atgctaaaaa catagtcttt
    13021 actggagctg gtgataggaa tcgaacctac aacctgctga ttacaagtca gctgctctac
    13081 cgttgagcca caccagcaca cctattttat tgtaaattag taaaactaat ttttaaaagt
    13141 ta
//
LOCUS       DAMJXI010000091        12403 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.096, whole genome shotgun sequence.
ACCESSION   DAMJXI010000091 DAMJXI010000000
VERSION     DAMJXI010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12403
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.096"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            331..1266
                     /locus_tag="PC465_003318"
     CDS             331..1266
                     /locus_tag="PC465_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HDF2650595.1"
                     /translation="MIRYYKTIDSKLEKLSFFEDGCWINLVEPNHSEINEISNLLNID
                     VESIESALDEEERSRIDVEDNHTLILIDIPVDESDSNSSHYTTIPLGIILTEEAIVTV
                     CDAQTKILNDFIVGHIKDFFTFKKTRFLLQILHKNAAYYLHYLRKINKMTIIIEREIY
                     KSMKNKELVQLLELEKSLVYFSTSLKSNELVLNKMVRTAGIKKYPDDEDLLEDVIVEN
                     RQALDMAKIYGDILSRIMDAFSAIISNNQNNVMQILTVVTLIFSIPTIISGFFGMNVI
                     NMPFSNNPNGFWIILLITSIICIVITFFMSRNKLL"
     gene            complement(1358..3229)
                     /locus_tag="PC465_003319"
     CDS             complement(1358..3229)
                     /locus_tag="PC465_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HDF2650596.1"
                     /translation="MKNTKFSIKKIKNISNDPKVVHTKGALLEKMGKMESAIELYKSA
                     ALDNYVKSQYTLGNIYESKKQFKEAEKWYSMAYKSGSEDAAFDLGNMYYKLDGYEYAI
                     YWYEKIANLGYLQAQNNLGVCHFKMKDFVRCEKWLKTAADKNLGKACFNLGVLYTFLE
                     KDDEAYEYYKKGSVLLDDDAKYNLAILNGKKKDNKSTVSLYKQLYKSGHMKGCFNLGM
                     IMEINDNLEDAEKYYKKSADRDDVKSEYRLAYVYDRKEELGDAIYYYEKAIEKNHTLS
                     KYRLANLYNRENEIEKAKTYYKMAAEDDITEAKNNLAGIYFEEKDYENAIKYYEDAIA
                     VGCKSSLENLGDLYYQNQDIEKAISYYSRIPNNVSCQIKLGNIYEDLNNIEEAISWYK
                     KASENGDTRSSYRLGCIYESLGNTKNARKYFEMASSKNHMNARIHLGRIYFREGKLEE
                     SKMMFDTPANENNVYAQHMVGLIYDMFYKDYVNSKFWYEKARAQGCVESIYNLGQIYL
                     KLNDDAEAEKYYKEGIKYGSKKCEYMLAGLYYKKSLDMYVSLANEEYDNCEEIVEGFP
                     NLNIDFDEVLIPPFKLQEEVIDEEEYVPIYILNIKESLDSMLEGLETEMIIDEEHDS"
     gene            3419..4345
                     /locus_tag="PC465_003320"
     CDS             3419..4345
                     /locus_tag="PC465_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HDF2650597.1"
                     /translation="MNFSNIFIQVAVLFIIILVGYFVRKFNLLDEHCTSKLSTLTMTV
                     FLPSMIISSMQINFDSKMIQKILLLLFTSLIMYIVSIIIAFLLKYILKCNDKKDLGIY
                     QYIVVFSNVAFMGYPVIEAVLGHEAIFYTAIFNLPFNLFSFTLGIYLLSKGSTSRGFS
                     IKSLISPATIAIVIGLFLFVTGLRLPQFINEPLEMLGSITTPISMIIIGSLLANSSAL
                     DCFVNKKLYIVTFIRLLVLPVIVYFILKGWINDKMILAIPVVISSMPAAANTAIMANQ
                     YDSNITLASQCVFFTTLFSVISIPFISILLLS"
     gene            4484..4630
                     /locus_tag="PC465_003321"
     CDS             4484..4630
                     /locus_tag="PC465_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650598.1"
                     /translation="MDMDLLFKIVFAIVAIGVSVKIIKTVASLAFKIALILLIILFVY
                     RMFL"
     gene            complement(4735..5259)
                     /locus_tag="PC465_003322"
     CDS             complement(4735..5259)
                     /locus_tag="PC465_003322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2650599.1"
                     /translation="MSKPIDITIRPIRREDAQAFNEIRRTYSVMRNTLALMSDRVDKT
                     EAMLASLGENDYMFVAETNNNGGKDVIGFAGLHVNSSPRLRHSAEIGISVAENYQGRG
                     VGKKLMEQLLDIADNWIMLTRVGLEVIVDNEKGLNLYKKLGFEIEGTKKYAVIRDGKF
                     EDVYIMGRYNKNLI"
     gene            complement(5312..5536)
                     /locus_tag="PC465_003323"
     CDS             complement(5312..5536)
                     /locus_tag="PC465_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650600.1"
                     /translation="MIIKLTKDNFNFRFKQYEGMFFHAEVVEGMESIRYKITKDKEGT
                     ELKEFGSTHIKDNMIYVPQVEAYIDLNSIK"
     gene            5733..6857
                     /locus_tag="PC465_003324"
     CDS             5733..6857
                     /locus_tag="PC465_003324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3810 domain-containing protein"
                     /protein_id="HDF2650601.1"
                     /translation="MSKKTKYFSLILFPIALLLNFIASKVPNIVEKYYSQFIDKIIVQ
                     ILSKVSGIFPFSLYEITMYIIVISIFLFLCCTLSTIFNKKKKLNIYLKNSILNILSIV
                     SIVYFLFIVLWGINYNRIPLETTLINNYNLKNNTSIQSKQYSVKELTKLYKFLVIKAN
                     ETRKLTLQDKNGIVKSNTDYNGVINRAQLGYDNILDILPSVSGSYSKPKYIISSNLMC
                     YTGITGIYFPFTGEANVNIAIPDLYIPCTVEHEMAHQRGFASEDEANFIAYLTSIKHP
                     NIDFNYSGYILALNYTASALSKVDYNAYVDISAGISDSVRRDLKNESEFWQKYEGKIN
                     EISNEFNNSYLKANGVTEGTQSYGKMVDLLLTYYELYPYN"
     gene            complement(7331..8155)
                     /locus_tag="PC465_003325"
     CDS             complement(7331..8155)
                     /locus_tag="PC465_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650602.1"
                     /translation="MRYKKISSLPILVVALLITGTTTTFSLSTTNSEKTNVYLANTVS
                     TVTKKVSDIQSSKGLVYNENIPLFINNSKIQYDDTPYHWPSNVISLTNSSEKAIMDYE
                     ITCLAYDKNGKPLELYWDAQNVAADGEVGSVGFSPAGVDYGIVTGISPVSPKSYSHTY
                     RKMQQSPPQDIISMFEKQQGKAWVENWLKEWKQMEKEYAKQNAIAPGKNQNDAFLLFD
                     KWKQSTGEHGVKYIISCVKQVTFNDGSVWKNSAYENWLKSFQGKEVSNSVLENYYK"
     gene            complement(8503..9558)
                     /gene="ispG"
                     /locus_tag="PC465_003326"
                     /gene_synonym="gcpE"
     CDS             complement(8503..9558)
                     /gene="ispG"
                     /locus_tag="PC465_003326"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HDF2650603.1"
                     /translation="MSYERRKTREVSVGTVKIGGENPISIQSMTNTDTRDADATIAQI
                     KRLEEAGCDIVRVAVPDIKAAKNIAKIKSSVNIPIIADIHFDYKLALEAIEQGVDGIR
                     INPGNIGSIERVKMVVEKCKERNLKIRIGVNGGSLEKELLKKYGSATAEALVESAMGH
                     IKILEDLDFHNIVISLKSSDIYKTVDAYELISKKVDYPLHIGITESGSVHKGTIKSSI
                     GVGALLLKGIGDTVRISLTGDPVEEVIVGKQILRSLGLLNDKIKVISCPTCGRCNIDL
                     ISVVNEVEEKIGSMEKNITVAIMGCAVNGPGEAREADIGIAGGKGEGLLFKKGEIVRM
                     IDGNKLVDELLEEIEKL"
     gene            complement(9740..10744)
                     /gene="rseP"
                     /locus_tag="PC465_003327"
     CDS             complement(9740..10744)
                     /gene="rseP"
                     /locus_tag="PC465_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HDF2650604.1"
                     /translation="MTIIAALILFSIIVLIHELGHFIFAKRSGIKVNEFSIGMGPKIY
                     SVKKDTEYSIRALPIGGYVSMEGEDEEQISPNSFGNKSILQRFSTIVAGPIFNIILAA
                     ILLVPVFLYIGSPTTKLGKIMPDTPAQAVGLQVGDKINKINGNSVKTWDEVANIINTS
                     SGGELKLSITRDGSDKVVNVTPKNNNGKYEIGIQPQREKDFLGSIVNACKTTVDMTKQ
                     MLTFLGQMITGRVPGGIGNAVAGPVGVIGMVSDAARTGIINVVYLAAVISLNLGIVNL
                     LPIPALDGWRILMLLLEAVRGGKKLDPNKEGMINVVGFGALMLFMLFITYKDILRLFQ
                     "
     gene            complement(10757..11911)
                     /locus_tag="PC465_003328"
     CDS             complement(10757..11911)
                     /locus_tag="PC465_003328"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HDF2650605.1"
                     /translation="MKKISILGSTGSIGKQTLDVVRDNRDKFEIVAISANSNIELLLE
                     QIVEFKPKYVTVFEENKALKLKEMLPKNIEIEVLAGMEGLKIISSLDEVDVLLTAVVG
                     MIGLVPTLCAIKKGIDIALANKETLVTAGELVMKEAEKYNVNILPVDSEHSAIFQCLN
                     GENKKNIEKIILTASGGPFRGKKKGELANITKNEALKHPNWSMGRKISIDSSTLMNKG
                     LEVIEARWLFGVEQENIDVVVHPQSIIHSMVQYTDSSIIAQLGCPDMRLPIQYALTYP
                     DRMESSFERMNFSKFSTLTFEEPDLETFPCLKLAYECLKMGGTYSSVLNSANEVLVSE
                     FLEDKIGFYDIPYYIEKTLEVHSSISEPTLEEILETDRWSRAYVANLIKK"
     gene            complement(12075..12278)
                     /locus_tag="PC465_003329"
     CDS             complement(12075..12278)
                     /locus_tag="PC465_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2650606.1"
                     /translation="MISYAPLWKLLIDKKIKKMEFVNISGISISVLGRLGNDKSVSMD
                     TMEKICLALDCKIEDVVEIKKGI"
BASE COUNT         4130 a         2089 c         1294 g         4890 t
ORIGIN      
        1 aaattaaata taacttatat actttatgtg taaattgtgg taaaaatatt atttaatcaa
       61 atcaaaactt gatttatata cctggaaaag gtattatatt aaagagtgct taaaatacgc
      121 atttcataaa tagctatata taaaataata aataaggaga gtgatgggca atggatacta
      181 gtccgttgcg gagagaattt tttacatttt catcacttaa taatatctaa aatcaaaact
      241 aatacatata ttcagttata taaattagtt aattaataga tactattaaa tgatgagatt
      301 tatataaaac tgaataaagg atgtgttgcc atgataagat attacaaaac tatagattca
      361 aaattagaga aacttagttt ttttgaagat ggctgttgga taaatcttgt tgaacctaat
      421 catagtgaaa tcaacgaaat ttctaattta ttaaatatag atgtagaaag catagaatct
      481 gcactagatg aagaagaacg ctcaagaata gatgttgaag acaatcatac tcttatactt
      541 atagatatac cagtagacga aagtgactct aattcttctc attatactac aataccctta
      601 ggtattatac taactgaaga agctattgta acagtttgtg atgcacaaac taagatttta
      661 aatgacttta tagttggtca tattaaagat ttttttacgt ttaaaaagac tcgctttttg
      721 cttcaaattc ttcacaaaaa tgcagcttat tacttgcatt acttaagaaa aataaataaa
      781 atgacaatca taatagagcg agaaatttac aaatcaatga aaaacaaaga attggttcaa
      841 ttattggaat tagaaaaatc tttggtatac ttctctacct cactaaaatc taatgaactt
      901 gttttaaaca aaatggttag aactgctggt ataaagaagt atccagatga tgaagaccta
      961 ttagaagatg ttatagttga aaatagacag gctcttgata tggctaaaat atatggagat
     1021 atattgagta gaattatgga tgctttcagt gcaattataa gtaataatca gaataatgtt
     1081 atgcaaattt taacagtagt tacactaatt ttctcaatac ctacaataat atcaggattc
     1141 tttggtatga atgtcatcaa catgccattt tctaataacc caaacggatt ttggataata
     1201 cttcttatta cctctataat atgtatagtg attacatttt tcatgtcaag aaataagcta
     1261 ttataaaata ttaataaaaa agccattaga attaattgat ttacatttat cctaatggct
     1321 tttatatatt taaatctata taatcctata atacttttta actatcatgt tcttcatcta
     1381 taatcatttc agtttcaagc ccttctagca ttgaatctaa actttctttt atatttagta
     1441 tataaattgg tacatactct tcttcatcta ttacctcttc ttgcaactta aatggaggaa
     1501 ttaatacttc atcaaagtct atatttaaat taggaaagcc ttctactatc tcttcacaat
     1561 tatcgtactc ttcatttgct aaagaaacgt acatatctag gctcttttta taataaagac
     1621 ctgcaagcat atactcacac ttcttacttc catatttaat accttcttta taatatttct
     1681 cagcttctgc gtcatcattt aattttaaat aaatttgacc taaattatat attgattcaa
     1741 cacaaccttg tgctctagcc ttttcatacc aaaatttaga atttacataa tctttataga
     1801 acatatcata aattaatcct accatatgtt gagcatacac attattttca ttggcaggtg
     1861 tatcaaacat cattttagac tcttccaatt taccttctct aaaataaatt ctacctagat
     1921 gtatacgagc attcatatgg tttttgctac ttgccatttc aaaatacttt ctagcatttt
     1981 ttgtatttcc taagctctca tatatacacc ccaatctata actagacctc gtatctccat
     2041 tttcagatgc tttcttatac caacttatgg cttcttcaat attatttaaa tcttcataga
     2101 tatttcctaa tttgatttga caagatacat tatttggaat cctcgaataa tacgaaatcg
     2161 ctttttctat atcttgattc tgataatata aatcccctag attttcaagg gaacttttgc
     2221 atccaacagc tatagcatcc tcataatatt taatagcatt ttcataatct ttttcttcaa
     2281 aatatatacc tgccagatta ttttttgcct ctgttatatc atcttcagca gccattttat
     2341 aataagtttt tgccttctct atctcatttt ctctattata taaattagca agtctatact
     2401 tagaaagtgt atgatttttt tctattgctt tctcataata ataaattgca tctcccagct
     2461 cttcttttct atcatataca tatgcaagcc tatactcaga cttcacatca tctctatcag
     2521 cactcttttt ataatacttc tctgcatctt ctaaattatc atttatttcc ataatcatac
     2581 ccaagttaaa gcaacctttc atatgacctg acttgtacaa ctgtttatat aaacttactg
     2641 ttgatttatt atctttcttt tttccattta atattgctaa attatatttt gcatcatcat
     2701 ctaaaagcac agaacctttt ttatagtatt catacgcttc atcatctttc tccaaaaaag
     2761 tatataatac ccctaaatta aaacaagctt tacctaaatt cttgtctgct gctgttttta
     2821 accatttttc acaccttaca aaatctttca ttttaaaatg gcatacacct aaattatttt
     2881 gtgcttgtaa ataacctaaa tttgctatct tttcatacca atatatagca tattcatagc
     2941 catctaactt atagtacata ttacctaaat caaaagcagc atcttcactt ccacttttat
     3001 atgccattga ataccacttt tctgcttctt taaattgttt tttactttca tatatatttc
     3061 ctaaagtata ttgagatttt acgtaattat ccaatgcagc actcttatac aactctattg
     3121 cgctttccat cttacccatc ttttcaagga gggcaccctt agtatgtacg actttcgggt
     3181 cattagatat attttttatt ttttttatag aaaattttgt atttttcatt attcgctacc
     3241 tacccatttt ataaaatata ttctctcaaa cattattata cattataatc tacaattaat
     3301 gctataatat tgaattttta ccttttgtca ctatattgta acattaaatt ttaaatttta
     3361 taatcattag attttattat gtaattggta tataatgtat atataggggg gacattttat
     3421 gaatttcagc aatattttta tccaagttgc agttttattt ataattattt tagttggata
     3481 ttttgtcaga aaattcaact tattagatga gcactgcaca tctaagcttt caactttgac
     3541 aatgacagtt tttttaccat caatgataat tagctccatg caaattaact ttgatagtaa
     3601 aatgatacaa aaaatactat tgttattatt tacatctttg attatgtata tagtttcaat
     3661 tataattgca tttttattga aatacatttt aaaatgtaat gataaaaaag atttgggaat
     3721 atatcagtat atagttgttt tttcaaatgt tgcttttatg ggttatcctg taattgaagc
     3781 agttttaggt catgaagcaa tattctatac tgcaatattc aatttgcctt ttaacttatt
     3841 ttctttcact ttaggaattt atcttttatc taaaggcagt acaagtagag gtttttcaat
     3901 aaaatcactt ataagccctg ctacaatagc tattgttatt ggactttttt tatttgtaac
     3961 aggacttagg ttaccccaat ttataaacga gccacttgag atgttgggaa gtataactac
     4021 accaatatcc atgattatca ttggaagctt acttgctaat tcttcagctc tcgattgttt
     4081 tgtcaacaaa aaattatata tagtcacttt tataagatta ttggtacttc ctgtgattgt
     4141 gtattttatt ctaaaaggat ggataaatga taagatgatt ttagctatac cagtagtaat
     4201 ttcttcaatg cctgctgctg caaatactgc tataatggct aatcaatatg actccaatat
     4261 aacactagct tcacaatgtg tgttttttac aacactattt tcagttatat ctataccttt
     4321 tataagtatt ttactcttat cttgatttat ttttttatgt attatataat aacatattca
     4381 ataaattaca aatataaaca ttttattgta gtatattgat ggaatttttt cctagatatt
     4441 tgtcaataat atctatatgt attatagaat aggaggctta aatatggata tggatttact
     4501 ctttaaaata gtatttgcta tagttgctat aggtgtttct gtaaaaatca ttaaaactgt
     4561 tgctagttta gcttttaaaa tagcgttgat attgctaata attttatttg tatatagaat
     4621 gtttttgtaa acatttaaaa ataagttttt taacacaata gagaagtaaa atagattatc
     4681 tttaatgtaa attttttatt aaagacactc tattttactt ctctattagc ttctttaaat
     4741 taaattttta ttatatcttc ccataatata aacatcttca aattttccat ctctgattac
     4801 agcatatttt ttagttccct ctatttcaaa acctagcttt ttatataaat ttaatccctt
     4861 ttcattatcc acaattactt ctaatcctac tctagttaac ataatccaat tatctgctat
     4921 atctaaaagt tgttccataa gcttcttacc tactcctctt ccctgataat tctctgcaac
     4981 acttattcct atttctgcgc tatgtctcaa tcgtggagaa gaatttacat gtaacccagc
     5041 aaaacctatt acatcttttc ctccattatt attagtttca gctacaaaca tataatcatt
     5101 ttctcccaaa gaagctaaca tagcttcagt tttatcgact ctgtcactca ttaatgccaa
     5161 agtatttctc ataacactgt atgttcttct aatttcatta aaagcttgtg catcttctct
     5221 tcttataggt cttattgtta tatctatagg cttactcata ttagattccc cctcaaacat
     5281 aatctttatt tttaattaaa attttacatc tttattttat actgttcaaa tctatgtatg
     5341 cttctacctg aggtacatat atcatattat cttttatatg tgtacttcca aattctttta
     5401 attctgtacc ttctttatcc ttagttattt tatatctaat ggattccata ccttcaacta
     5461 cttcagcatg aaaaaacata ccttcatatt gtttaaatct aaaattaaaa ttgtctttag
     5521 taagttttat tatcatattt ttatctactc cttatataat tgatattttt cttattatta
     5581 gttgtatata tactgcttat tcatattaat atattataac ttatcattta tttagtataa
     5641 agttataaat agatatattt atacttattt tacaatcttt cttcaattga tatataatat
     5701 gtttatataa actaatgtat gtgaggtgaa atatgagcaa aaaaacaaaa tatttttctt
     5761 taattctctt tcctattgct ttgcttttaa attttatagc cagtaaagtt ccaaatattg
     5821 ttgaaaaata ttactcccaa ttcatagata aaataattgt acaaatattg agtaaagttt
     5881 ctggaatttt cccattttct ctctatgaga ttacaatgta cataatagtt atatctatct
     5941 tcttattttt atgttgtact ttatctacaa tttttaataa gaaaaaaaaa ttaaacatat
     6001 atttaaaaaa ttccatttta aatatattat ccattgtatc aatagtctac tttcttttta
     6061 tagtgctttg gggaataaac tataatagga ttccactaga aaccacactt ataaataact
     6121 ataatttaaa aaacaatacc tctatccaat caaaacaata tagtgttaaa gagcttacta
     6181 aattatataa attccttgta attaaagcaa atgaaactag aaaactcaca ttacaagata
     6241 aaaatggtat tgtaaaatct aatacagatt ataatggtgt cataaataga gctcaactag
     6301 gatacgataa tatcttggat atattaccta gtgttagtgg tagttattct aagcctaagt
     6361 atattatttc atcaaatcta atgtgctata caggaataac tggtatatac tttcctttta
     6421 caggtgaggc aaatgtaaat atagcaatac ctgacttata tattccttgt acagttgaac
     6481 atgaaatggc acatcaaagg ggatttgcta gtgaagatga ggctaatttt atagcgtatc
     6541 ttacttctat aaaacacccc aatattgatt ttaactattc tggatatatt ttagctttaa
     6601 attatactgc ttctgcttta agtaaggttg attataatgc atatgttgat atttctgctg
     6661 gcatttcaga ttctgtccgt agagatttaa aaaatgaaag tgaattttgg caaaaatatg
     6721 aaggtaaaat taatgaaatt tctaatgagt ttaacaattc ttacttaaaa gctaatggcg
     6781 ttactgaagg tactcagagt tatggtaaaa tggttgattt attgctaact tattatgaat
     6841 tatatccata taactaaaca ctacaattca aaattttatt catatacagc tgatattaaa
     6901 tcagctgttt tctatttaaa taaattattt aacttcaagc aatcttatat aatttgatag
     6961 tacttatact atctgtataa catttcaatt ctaactattt tagttaaaac atttctatta
     7021 tcttttttaa taaatgtttt aactaaaatt tttaaaacat aaaacttcca cattatttca
     7081 ctatctatat aaaaatctaa aaattcacat ataaaattac ataactaaaa aatcataaat
     7141 ttatagaaaa catatattca aaataaaaaa gcatgtatca aaacttgaca catgcttata
     7201 atcttatgta tatatatcat tttgtcacaa taaaaattta cttgtaacac tgatattttt
     7261 aaacaaaata gtccttattt aattaaatta acattaatta aattcgtact cattttgcta
     7321 tcattaaaca ttacttatag taattttcta atacactatt tgaaacttcc ttcccttgaa
     7381 aacttttcaa ccaattctca tatgctgagt ttttccatac actaccatca ttaaatgtta
     7441 cttgttttac acaagatata atgtacttta caccatgctc tccagttgat tgtttccatt
     7501 tatcaaacaa tagaaaggca tcattttgat tcttacctgg tgctattgca ttttgctttg
     7561 catattcttt ctccatttgt ttccattctt tcaaccaatt ttctacccat gccttgcctt
     7621 gttgtttttc aaacatactt attatatcct gtggtggtga ttgttgcatt tttctataag
     7681 tatgtgaata tgattttgga gacacaggag atatgcctgt aacaatacca tagtctacac
     7741 cagctgggct aaatccaaca cttcctactt cgccatctgc tgccacattt tgagcatccc
     7801 aatatagctc aagtggtttt ccatttttat catatgctaa gcatgtaatt tcataatcca
     7861 taattgcctt ttcactgcta tttgttaagc ttataacatt gctaggccaa tgatatggag
     7921 tatcatcata ctgtattttg ctattattta taaataatgg aatattctca ttataaacaa
     7981 gacctttact actttgaata tctgatacct tctttgtgac agtacttacc gtatttgcta
     8041 agtatacatt tgttttttct gaattggtcg tactaagaga aaatgttgtt gtcgttccag
     8101 taatcagcaa agcaacaact aaaataggta agctagatat ttttttatat ctcacagttc
     8161 ttcacctctt tttctattaa cttataataa aacaatttac caaaacatta aaatctatgt
     8221 taacataatt taccaactgt tctagtaact atatcctatc atagttacta tcaagtttca
     8281 atactattga tggaaatttt cactatatta aatctttttt taattttata aatttacaat
     8341 atgatttaac tcatacatat atagtcaaat tagaatataa gtttcttaca tttaatgaag
     8401 tttataaaat aaaaaatgac tagataatta aatactgtaa ataaaaactt attacaaaag
     8461 tatttaaaaa tctagtcaat taatatatat atgaattgta tactataatt tttcaatctc
     8521 ttctagcaac tcatcaacta atttgttacc atcaatcatt ctaactattt cacccttttt
     8581 aaataaaaga ccttcacctt tacccccagc aatacctata tctgcctctc tggcttcacc
     8641 aggtccattt acagcacagc ccataattgc aacagtgata tttttttcca tactaccaat
     8701 cttttcttca acctcattta caacactaat taagtctata ttacatctac cacatgtagg
     8761 gcatgatata actttaatct tatcatttaa aagtcccaaa cttcttaaaa tctgtttacc
     8821 aacaataacc tcttcaacag ggtcgcctgt taaagatatt ctaacagtat ctccaattcc
     8881 tttaagaaga agtgctccta cccctataga agactttatt gttcctttgt gaacacttcc
     8941 agattctgta attccaatat gaagaggata atcaactttt tttgatatta attcatatgc
     9001 atcaacagtt ttataaatat cggatgattt tagagatata actatattat gaaaatctaa
     9061 gtcttcaaga atcttaatat gtcccattgc actttcaact aatgcttcag cagttgcaga
     9121 gccatacttt tttaaaagtt ctttctctaa agaacctcca ttaactccaa ttctaatttt
     9181 taaatttctt tccttgcatt tctcaactac catcttaact ctctctatac ttccaatatt
     9241 accaggattt attcttattc catccacacc ttgttctata gcttcaaggg ctagcttata
     9301 atcgaaatgt atatctgcaa taattggtat atttacacta gactttatct ttgctatatt
     9361 tttagcagct ttaatatcag gaacagcaac tctaactata tcacaaccag cttcctctaa
     9421 tctctttatt tgagctattg tagcatctgc atctcttgta tcagtatttg tcatagattg
     9481 tatacttata ggattttctc ctcctatttt tacagttcct acacttactt ctctcgtctt
     9541 tcttctctcg taactcatat tccacctcta tatattattt tatattgaat ctctttaaat
     9601 attaaaatat tataacctac atgtatatta taaattaaaa agctatctag ttaaataaga
     9661 ataaatttca tatataaaaa ttaatttatt cttatttaaa actacatagc ctattttctt
     9721 aaaatctcta aaaactaaat cattgaaata atcttagtat atctttatat gtgataaaaa
     9781 gcataaataa cattaaagct ccaaaaccaa caacatttat catgccttct ttatttgggt
     9841 cgagtttttt accacctcta acagcttcta gtaacagcat aagtattctc catccatcaa
     9901 gtgctggtat tggtaataga tttactatac ctaaatttaa gcttatgaca gctgctaaat
     9961 acactacatt tatgatgcct gtacgagcag catctgatac cataccaata acacctactg
    10021 gtcctgctac agcattgcca atccctcctg gtacacgtcc tgtaatcatt tgacctagaa
    10081 atgttagcat ctgttttgtc atatctacag tagttttaca tgcatttact attgacccca
    10141 aaaagtcttt ttctctttgt ggttgaatcc ctatttcata ctttccattg ttatttttag
    10201 gtgttacatt tacaacttta tcacttccat ctctagttat actaagtttt aattctccac
    10261 cagaagaagt atttattata tttgcaactt catcccaagt cttaacagaa ttaccattaa
    10321 ttttatttat cttatctcct acttgaagcc ctacagcctg tgcaggagta tctggcatta
    10381 tctttcctaa tttagtcgtt ggagaaccta tatacaaaaa tactggaact aaaagtattg
    10441 ctgctaatat tatattgaat attggtcctg ctacaatagt actaaatctt tgtaatatag
    10501 acttgtttcc aaaagaattt ggacttattt gttcttcatc ttcaccttcc atgctgacat
    10561 atccaccaat tggaagtgct cttatagaat actctgtatc tttttttaca ctatatatct
    10621 taggccccat acctatagaa aactcattta ctttgatacc acttcttttt gcaaatataa
    10681 aatgtcctaa ctcatgtatt aatacaatta tactaaatag tattaatgcg gctattatag
    10741 tcataaattc accttcctat ttttttatca gatttgcaac ataagctcta ctccatctat
    10801 ctgtttctaa gatttcttct aatgttggtt cacttatgct actatgaact tctaaagtct
    10861 tctctatgta atatggtatg tcatagaaac caattttatc ctctaaaaat tcacttacta
    10921 aaacttcatt tgctgaattt aaaacagaag aataagttcc tcccattttt aaacactcat
    10981 atgccaattt taaacatgga aaagtttcta aatctggttc ttcaaaagtt aaagtactaa
    11041 attttgaaaa attcattctt tcaaagctac tttccattct atctggatat gtaagagcat
    11101 actgtattgg tagtctcata tctggacatc ctaattgagc aattattgag ctatctgtat
    11161 actgcaccat tgaatgaatt atgctttgtg ggtgaactac tacatctata ttttcttgtt
    11221 ctactccaaa taaccatcta gcttctatca cttcaagtcc tttattcata agcgttgaag
    11281 aatcaatact tatttttctt cccatactcc aatttggatg cttcaaagct tcatttttag
    11341 ttatatttgc aagttctccc tttttctttc ctctaaatgg accaccagat gctgtaagta
    11401 ttatcttttc tatatttttt ttattttctc catttagaca ttgaaatata gcactatgtt
    11461 cactatcaac aggaagaata tttacattgt atttttctgc ttctttcatt acaagttcac
    11521 cagcagttac caacgtttct ttattcgcta atgctatgtc tattcccttc tttatagcac
    11581 aaagagttgg gactaatcct atcataccta ctacagcagt taaaaggaca tccacttcat
    11641 caagtgatga tattattttt aatccttcca ttcctgctaa aacttctatt tctatatttt
    11701 taggcaacat ttcttttaat ttcaatgctt tattttcctc aaaaactgtt acatatttag
    11761 gtttaaactc tactatctgt tctagcaata attcaatatt actgttagct gatattgcaa
    11821 ctatctcaaa cttatctcta ttatctctaa ctacatccaa agtttgttta cctatagagc
    11881 ctgtagaacc taaaattgat atctttttca tataataatc ctttctaata ataaatatac
    11941 cctgtcaaaa cattataaca ctactaaaac aattattttt actattcata gaaatttcat
    12001 atattattcc acagattaaa attaatctat tattttttgt attttgtgga atattataaa
    12061 atattctagt attattaaat gccctttttt atttccacaa catcttctat tttacagtct
    12121 agtgctaaac atatcttctc cattgtatcc atagaaacag atttatcatt tcctagtctg
    12181 cctaaaacag aaatacttat acctgatata tttacaaatt ccattttctt tatttttttg
    12241 tcaattaaca atttccataa tggagcgtat gaaatcatgt tatcacctcg caaaatatat
    12301 tctatcacat tttatctatt ttggaaaatt ttcatctatt tagataaata attatttatc
    12361 taaatagatt tcaattatag tttattaaat ataaatatgt taa
//
LOCUS       DAMJXI010000092        12302 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.097, whole genome shotgun sequence.
ACCESSION   DAMJXI010000092 DAMJXI010000000
VERSION     DAMJXI010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12302
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.097"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            <1..321
                     /locus_tag="PC465_003330"
     CDS             <1..321
                     /locus_tag="PC465_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF2650607.1"
                     /translation="VEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDS
                     EITQYSFCTNGSHYAGEAGIRTIGFGPSKENLAHTIDEYIELDQLFKGAEGYYGILKS
                     VYKK"
     gene            337..1920
                     /locus_tag="PC465_003331"
     CDS             337..1920
                     /locus_tag="PC465_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HDF2650608.1"
                     /translation="MRTLIKHGLIVDGNKTPAYEGDILIENEKILKISQDLNEEADKV
                     IDAKGRVICPGFIDTHSHSDLVILVNPYNEVKIRQGITTEVLGQDGISMAPLPQEHIS
                     SWRKNLAGLDGESDEIDWKYETTENYLKMMDYNGVGLNETYLVPHGNVRMEAMGLEDR
                     PATKEEIQKMCEITERELKAGAIGLSTGLIYIPCAYSLTEEIIEMCKVVAKYDGVFVV
                     HQRSEADTILTSMEEIIEIGKQSGVKVHFSHFKVCGKANWKYIPQVIELLEKAEKEGI
                     RVSFDQYPYAAGSTMLGVVLPPWAHSGGTDKLIERLSDENERAKMKKDIANGIEGWDN
                     FIEFAGIDQIFVTSVKTEKNKDTIGKSLLEIGKMRGKDPLDATFDLLKEEENAVGMVD
                     FYGLEEHIIGFMKRDEQNVCTDGLLAGKPHPRAYGSFPKILGRYVRELNVLTIEEAVY
                     KMTKKAATSFSIKDRGELKEGYFADIVIFDKDTVSGCDDFINSMQYPTGIDYVIINGN
                     CVVEEGKYNKIKAGKVLKN"
     gene            1948..3276
                     /gene="ssnA"
                     /locus_tag="PC465_003332"
     CDS             1948..3276
                     /gene="ssnA"
                     /locus_tag="PC465_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HDF2650609.1"
                     /translation="MILVGNGRLISQDSLNPYMEDGCVVINDNLIEDIGTTEEMKAKY
                     PVHEFIDAGKKIIMPGLINSHMHIYSSFARGMAVPGKPSENFLEILNNLWWRLDKQLT
                     LEDTKYSAYATYIECIKNGVTTVYDHHASPNAIEGSLFTISDVAKDLGIRTCLCYEVS
                     DRDGGNTIQQGINENVNFIKYAQKDDTDMIKGMFGLHAAFTLSDDTLNKCASEIAGLD
                     TGYHVHVAEGLADLQYNVDKYGKRVLERFNDFGVLKEKTIAVHCIYISAEEISLLNKT
                     NTFVVHNPESNMGNAVGCSPAIELLKRGVTVGLGTDGYTSDMFESLKVANIIHKHHLK
                     DPRVGFEESQTMLFDNNRKIAKAYYKNDLGVLKKGAYADVIVVDYIPHTPLTENTIGG
                     HTIFGMSGRSVDTTIISGKVLMKDRKLINIDEESILAKSRELSQNLWNRI"
     gene            3475..4827
                     /locus_tag="PC465_003333"
     CDS             3475..4827
                     /locus_tag="PC465_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HDF2650610.1"
                     /translation="MSRDKSPKIAPVDERLPVSKSWVFSLQHVLAMCAGAVAVPMMIG
                     SAARLDHASIVFLINACLFMAGIGTLIQSVGIGNIVGAKIPVIEGTSFAAVAGMTAIA
                     SSYSDSQVAIQTVFGSVIVAGLFCILLAPVFEKLIRFFPSVVTGTVVMVIGISLFPVG
                     IKWITDNKLEAVEPNSLALALAVLAITLLSFKFLKGIWNSTAILVGIVLGTLLSMAVG
                     MADFSAVNGVGWLNLNVPLKFGMPRFEPSAILSLCLIMLVLMTESVGNMIAIHEMVDK
                     EVTGKNIKRGLFGDGISTALSGIFNSFPITPFGQNTGIVGLTGIKSRFIAVYAGVILL
                     VLGFLPKFAAIIGAIPKPVLGGVGFAMFGMVMVGGVKTLSKVKFDGTKNGVIVAVSVG
                     LSMIPLTNPDFYHNFPTWVQTIFHSGITTGSLSAVLLNIFFNELGSKKEKNNKVEEAK
                     "
     gene            5019..6128
                     /locus_tag="PC465_003334"
     CDS             5019..6128
                     /locus_tag="PC465_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2650611.1"
                     /translation="MANLKVNLYGMEFLNPIMTAAGPGAKDGALCQEAAKGGAGAICT
                     KTISVLPADVPRPCMAKTNSGFLNTELWSELPKEQWIEEEYKKVKETGLPVIVSMGYS
                     AEQIAEVAPLVKPYADAVELSTHYVGTDVAPIVNALKAAKAVLDVPVFMKMSPHTDIQ
                     TIAKAVEEAGADGLVMINSFGPCMAIDVNTGYPIMGSKAGYGWLSGAPIRPLAIRCIY
                     EASQVVNIPIIGVGGITCGKDVAEMMMAGASAVQVCTEAILKGPSIYGKIAKELNEFL
                     DENGYADVNEIKGLTHKKMAARGFRTHSVAPVVDDNKCIKCKQCVTSCVYEALEVTDK
                     LNIDADKCFGCGLCVTRCPKGALSICYNQVEAMNE"
     gene            6411..7802
                     /gene="hydA"
                     /locus_tag="PC465_003335"
     CDS             6411..7802
                     /gene="hydA"
                     /locus_tag="PC465_003335"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HDF2650612.1"
                     /translation="MGIVLKGGKVVTSEKTYCADVRIEDEKIVDIGLDISKENDEIVD
                     VSDSYVIPGGIDTHTHFDLDTGVTKTADNFETGTKAAIVGGTTTILDFATQDKGCSLK
                     DGLEEWHEKAKDKSYSDYGFHMAITDWNDSVCNEMEDMVKEGVSSFKLYMAYKGSLQV
                     DDGVIFEALRKAEEIGGIIGFHCENGDIICELVDKAKSENNLSPKYHQLTRPAIMEAE
                     ATSRLMKIAEVANSKVYVVHLSCKESLEEVLKAKQRGVDVIVETCPQYLLLNDELYDL
                     DGFESAKYVMSPPLRNKENNEILWNAILDNQIDTIGTDHCSFNYKGQKELGINDFSKI
                     PNGSPGVEHRMSLLYTYGVCKNKISINKMVEVTSTNPAKLFGMYPNKGTIEIGSDADI
                     LVLNPNKKSKIEAKKQLQNVDYTPYEGYEVDCQIEHVYLRGKEVVRDGELICNTPSGR
                     YINRRLTKGAREW"
     gene            7796..10357
                     /gene="xdh"
                     /locus_tag="PC465_003336"
     CDS             7796..10357
                     /gene="xdh"
                     /locus_tag="PC465_003336"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent xanthine dehydrogenase"
                     /protein_id="HDF2650613.1"
                     /translation="MVEFILNGEKVVAKEGKKLLDFLREDMNITSVKNGCSEGACGTC
                     MVIIDGKATKACVFKTDKLVGKNITTIEGLSERERDVFAYSFASQGAVQCGFCIPGMV
                     ISSKALIDVNNNPTEDDIKKALKGNICRCTGYVKIIKAVDLAAKIFRENIDVPKVNCK
                     GLVGENLPRVDAVGKALGYSEYVDDMRIEGMIYGSAVRAKYPRALVKKIDIEEAKAYP
                     GVVAVLTAKDIPGTIKVGHLKKDWDTLIPEGEITRYLGDGIVLVAAETREALEEAKKL
                     VKIDYEELTPLSTTADALREDAPKIHETGNILVKEHLVRGNAKEKIENSKYVVTKRYT
                     TPATEHAFLEPECAVAGPYEEDGVIIYSTDQGVFATQHECADMLGLPYEKVRVINKMV
                     GGGFGGKEDMSVQHHAALLAYHTKRFVKVQLTRKESIIVHPKRHATEMEFTTACDENG
                     YLTGMKATIISDTGAYASLGGPVLQRLCTHAAGPYNYQDIDITGTAVYTNNPPGGAFR
                     GFGVTQSCFATECNLNLLAEMVGISPWEIRYKNAIRPGQVLPNGQFADEGTAMAETLE
                     AVKEEYEKHPRAGIACAMKNSGVGVGIPDVGRCRLVIKDGKVHIRTSASCIGQGLGTV
                     MTQVVCETANLLPENIVHEVPDTHLTPDSGNTTASRQTVFTGEATKVASNKLKEALDS
                     GKTLLDLEGEEFYGEYESITDKMGCDKENPVSHVAYGYATQVVILDENGKLEKVVAAH
                     DVGRAINPISLEGQIEGGVVMGLGYALTEDYPVVNSVPTAKFGTLGLFKSTDIPEIQA
                     LIVEKNKDLLAYGAKGVGEICTVPTAPAVQNAYYVFDKEFRTELPLQNTPYSKKK"
     gene            10509..11855
                     /gene="rpoN"
                     /locus_tag="PC465_003337"
     CDS             10509..11855
                     /gene="rpoN"
                     /locus_tag="PC465_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HDF2650614.1"
                     /translation="MNFNNSLELTQSQKLIMTTQLKQSLSILNMSKLELEEEIKREAE
                     NNPLVEVEKSGEINWEEYIKDMDRSRRLDRTEISYNPDNEVNLENLVKYSSNLYEDLK
                     FQISLYKLTDKELEVCEYIIDSLDEDGYLRTEEKVIVDTLKIDEELFEKCLISVQQLE
                     PSGVGARSLSECLMIQMASLGIYNEILEEIVTKDLNLIANNKYKEISKKYNMSLQKCV
                     ELINIIKTLDPKPGRTCSVEKSVYIQPDVTVEKIDDEFIVYLNEKDSYQIRINSYYKD
                     ILKNSQSDESAKEFIKERLNSATGLMKNIESRKTTVLKIAEEIVKAQDEFLRKGTKYI
                     KPLKMKDIAEKLEFHESTISRGVNGKYMLTPFGVYEFRYFFSSAIETENNEMASSTSI
                     KKIIKETIKDENKKKPLSDDHISKLLKEKGINVARRTVAKYREELGIPSSSKRKEY"
BASE COUNT         4909 a         1424 c         2496 g         3473 t
ORIGIN      
        1 gttgaaaaag ctgattgcta tacaggaaat actatagaaa gtgaaagatt cttcccaggt
       61 tggttatatg atgaagaaga tgaatttgtt caagcagcgt ataagggatt aaaagaagct
      121 ggaatagatt cagaaataac tcaatactca ttctgtacga atggaagtca ctacgcaggt
      181 gaggctggaa taagaactat aggatttggt ccttctaagg aaaatcttgc tcatacaata
      241 gatgagtata tagaattaga ccaattattc aaaggtgcag aaggatatta tggtatatta
      301 aaatcagttt ataaaaaata attaggagat ggttttatga gaactttaat aaaacatggg
      361 cttatagtag atggaaataa aacaccagca tatgaaggag atattttaat agaaaacgag
      421 aaaatattaa aaatatcaca agatttaaac gaagaagctg acaaagttat agatgcaaaa
      481 ggtagagtta tatgtccagg tttcatagat actcatagcc attcagacct agttatttta
      541 gttaatccat ataatgaggt aaagattaga cagggaatta caacagaagt gttgggccaa
      601 gatggtatat ctatggcccc tctacctcaa gagcatatat cttcttggag aaaaaattta
      661 gcaggtctag atggtgaaag tgatgaaatt gattggaaat atgaaacaac agagaattat
      721 ttaaaaatga tggattacaa tggggtaggt ttaaatgaaa cttatttagt acctcatgga
      781 aacgttagaa tggaagctat gggacttgaa gatagacctg ctactaaaga agaaattcaa
      841 aaaatgtgtg aaatcacaga gagagaatta aaagcaggag ctataggatt gtctactgga
      901 cttatatata taccttgtgc atactcattg actgaagaaa ttatagagat gtgtaaggta
      961 gtagcaaaat atgacggagt atttgtagtt caccaaagaa gtgaagcaga tacaatttta
     1021 acttcaatgg aagaaatcat agaaattgga aaacaatcag gagtaaaagt tcatttttca
     1081 cattttaagg tttgtggtaa agcaaactgg aagtatatac cacaagttat agagctttta
     1141 gaaaaagcag aaaaggaagg aataagagta tcttttgacc aatatccata tgcagcagga
     1201 agtacaatgc ttggagtagt tttacctcct tgggcacatt ctggaggaac tgataagtta
     1261 atagaaagat taagtgatga aaacgaaaga gcaaaaatga aaaaagatat agcaaatgga
     1321 atagaaggct gggataattt tatagaattt gctggaatag accaaatatt tgtaacaagc
     1381 gtaaaaacag aaaagaataa agatacaatt ggtaagagct tattagaaat tggaaaaatg
     1441 agaggaaaag acccattaga tgcaacgttt gatttattaa aagaagaaga aaatgcagtt
     1501 gggatggtag atttctatgg attagaagaa catataatag gattcatgaa aagagacgag
     1561 caaaatgtgt gtacagatgg tcttttagca ggtaaaccac atccaagagc ttatggttct
     1621 ttccctaaaa tactaggaag atatgttaga gagttgaatg tgttaacaat cgaagaagct
     1681 gtttataaaa tgactaaaaa ggcagctaca agctttagta taaaagatag aggcgaatta
     1741 aaagaaggat attttgcaga tatagttata tttgacaagg atacagttag tggttgtgat
     1801 gattttatca actctatgca gtaccctaca ggtatagatt acgtaattat aaatggaaat
     1861 tgtgttgttg aagaaggaaa atacaataaa attaaagcag gaaaagtact taaaaattaa
     1921 atcttagctt taaggaggaa taaatttatg attttagtgg ggaatgggag gctaataagc
     1981 caagattctt taaatcccta tatggaagat ggatgtgtag taataaatga taatctaatt
     2041 gaagatatag gtactacaga agaaatgaaa gctaaatatc cagtacatga atttatagat
     2101 gcaggcaaga aaataatcat gccgggtcta ataaattcac atatgcatat atacagctca
     2161 tttgctagag gaatggcagt tccaggaaaa ccttctgaga actttttaga gatactaaac
     2221 aatttatggt ggagacttga caaacagctt acactggaag atacaaaata cagtgcatat
     2281 gcaacgtata tagaatgtat aaaaaatggt gtaacaacag tttatgacca tcatgcaagt
     2341 ccaaatgcaa ttgaaggcag tttgtttaca atatcagatg ttgcaaagga tttgggaatt
     2401 agaacgtgtc tttgttatga agtgtctgat agagatggtg gaaatacaat ccaacaaggt
     2461 atcaatgaaa acgtaaactt tataaaatac gctcaaaaag atgatacaga catgataaaa
     2521 ggaatgtttg ggcttcatgc tgcatttaca ctatctgatg atacattaaa taaatgtgct
     2581 tcagagatag ctggtcttga tacaggttac catgtacatg ttgctgaagg actagcagac
     2641 ttacaatata atgtagataa atatggaaaa agggttttag aaagattcaa tgattttgga
     2701 gtactaaaag aaaaaacaat agcagttcat tgtatatata taagtgcaga agaaatcagt
     2761 cttttaaata aaacaaatac atttgtagtt cataatccag aatctaatat gggaaatgca
     2821 gttggatgtt ctcctgcaat agagttatta aaaaggggag ttacagtagg attaggaact
     2881 gatggatata ctagcgatat gtttgaatca ttaaaagttg ccaatataat tcacaaacat
     2941 cacttaaaag acccaagagt tggatttgaa gaatcacaaa caatgttatt tgataacaat
     3001 agaaaaatag ctaaagctta ttataaaaat gacctaggag tacttaaaaa aggtgcttat
     3061 gcagatgtta tagtagttga ttatatacca catactccat tgacagaaaa tacaataggg
     3121 ggacacacta tttttggaat gagtggaaga agcgtagata caactattat aagtggaaag
     3181 gtacttatga aagatagaaa gttaataaac atagatgaag aaagtattct agcaaaaagt
     3241 agagaattaa gtcaaaatct atggaataga atttaaataa ttgattatgc aaaattctat
     3301 gaagcaggaa ccctgtgact ttagtcatgg gaggttcaga ttaatataca agtaagaaac
     3361 aagaatttag atgttaaaaa cagagcttaa acaaaaatag gaatttaaat gaagtatata
     3421 aataaaaaat atacggaata gaatattaaa ttaaatatag aagggagacc caaaatgtct
     3481 cgagataaaa gccctaaaat agctccagta gatgaaaggt tacctgtatc caaatcttgg
     3541 gtattttcac tacagcacgt tttagcaatg tgtgcaggag cagtagcagt tcctatgatg
     3601 ataggaagtg ctgcacgact agatcatgct agtattgttt ttttaataaa tgcttgcttg
     3661 tttatggcag gtataggaac actcatacaa agtgttggta taggaaatat tgtaggtgct
     3721 aaaataccag taatagaagg aactagtttt gccgctgtgg caggtatgac agcaatagcc
     3781 tcatcatata gtgattcaca agttgcaata cagacagtat ttggctctgt aatagtagct
     3841 ggattgtttt gtatattact tgctccagta tttgaaaaat taataagatt tttccctagt
     3901 gtagttactg gaacagttgt tatggtaata ggtatttcac tatttccagt tgggataaaa
     3961 tggataactg acaacaaatt ggaagcggtt gaaccaaact cattagcatt agctttagca
     4021 gtattggcaa taactttact ttcatttaaa ttcttaaaag gaatttggaa tagcacagct
     4081 atattggtag gtatagtact tggtacacta ctttccatgg cagttggaat ggcagatttt
     4141 agtgcagtaa atggagttgg ttggcttaac ttaaatgtac ctttaaaatt tggaatgcct
     4201 agatttgaac catctgcaat actatcattg tgtttgatta tgttggtact tatgacggaa
     4261 tcagttggta atatgatagc tattcatgaa atggtagaca aagaagtaac aggtaaaaat
     4321 attaaaagag gtctatttgg agatggaata tctacagcat tatctggaat attcaattca
     4381 tttccaataa ctccatttgg tcaaaataca ggaatagtag gtcttacagg tataaaatca
     4441 agatttatag cagtttacgc aggggttata ttgctagtac ttggattctt accaaaattt
     4501 gcagcaataa taggagcaat acctaagcct gttcttggag gcgtaggatt tgcaatgttt
     4561 ggaatggtaa tggttggagg agtaaaaact ttaagcaaag tgaaatttga tggaactaaa
     4621 aatggggtta tagtagcagt tagtgttggt ttgtctatga taccactaac aaatcctgat
     4681 ttctatcata atttcccaac ttgggtacaa acaatattcc atagtggaat aacaacaggt
     4741 agtttatcag cagtgctttt aaacatattc ttcaatgaac taggttctaa aaaagaaaaa
     4801 aataataaag ttgaagaagc aaaataaaaa taaaacaagt aaaaatctat attgacttaa
     4861 agtcattaag tattaataaa aataattcag agatattaat aattcaacaa aactatctta
     4921 tattttaaat aatataaaaa agtaaataaa taacaaatac aaataaaaga atacaatcta
     4981 aatattaaaa atatttaatt taagggagag ataataatat ggctaattta aaagttaatt
     5041 tatatggaat ggaattttta aatccaatta tgacagcggc aggacctgga gcaaaagatg
     5101 gtgctctctg tcaagaggca gcaaaaggtg gagcaggagc tatatgtaca aaaactatat
     5161 ctgtattacc agctgatgta ccaagaccat gtatggcaaa aactaatagt ggttttttaa
     5221 acacagaatt atggtcagag cttccaaaag agcaatggat agaggaagaa tacaaaaagg
     5281 taaaagaaac agggcttcca gtaatagtaa gtatgggata ttcagcagag caaatagctg
     5341 aggttgctcc tttagtaaag ccttatgcag atgcagttga attatctact cattatgtag
     5401 gtacagacgt tgcaccaata gtaaatgctt taaaagctgc aaaagctgtt ttagatgtac
     5461 cagtatttat gaaaatgagt cctcatactg acattcaaac tattgcaaaa gctgttgaag
     5521 aagcaggtgc agatggactt gtaatgataa actcatttgg accatgtatg gcaatagatg
     5581 taaatacagg ataccctata atgggaagta aagctggata cggatggtta tcaggtgcac
     5641 caataagacc tctagcaata agatgtatat atgaagcttc tcaagttgta aatataccaa
     5701 taatcggtgt tggtggaatc acttgtggaa aagacgtggc tgaaatgatg atggctggag
     5761 caagtgctgt tcaagtatgt acagaagcaa tccttaaagg gccttctatc tatggaaaaa
     5821 ttgctaaaga attaaatgaa tttttagatg agaatggata tgctgatgtt aatgaaataa
     5881 aaggattaac tcataagaaa atggcagcta gagggtttag aactcattca gtagctccag
     5941 tagtggatga taacaagtgt atcaaatgta agcaatgtgt aacaagctgt gtatacgaag
     6001 ctttagaagt tacagataag ttgaacatag atgcagacaa gtgttttgga tgtggattat
     6061 gtgtaactag atgtccaaaa ggagctttaa gcatctgcta caatcaagta gaagctatga
     6121 atgagtaata attatataga attttggtaa ttaacttaga gtaataggta ttaggataat
     6181 aaaatatatc agataaacaa acacacatta tgcattaata atacagtcta aagttaataa
     6241 ttttattata ttgatttaac taaatattag tttagctgaa tattaattta attaggtatt
     6301 ggtttaatct taatatagat ttactgcgta taagtgaact aactagatta ctttaagtta
     6361 attttttcat ataaaataaa ttgatacatt acaagtaagg tggagtctat atgggaattg
     6421 ttttaaaagg tgggaaagta gtaacaagtg aaaaaactta ctgtgcagat gtaagaatag
     6481 aagatgaaaa aatagtcgat ataggtcttg atatatcaaa agaaaatgat gaaatagttg
     6541 atgttagtga ttcttatgtt ataccaggag gtatagatac acacacacac tttgacttag
     6601 atacaggcgt tactaagaca gcagataact ttgagacagg aacaaaagct gctatagtag
     6661 gaggaactac tactatattg gattttgcta cacaagataa aggatgttct ttgaaagacg
     6721 gattagaaga atggcatgaa aaagctaagg ataaatccta ttcagattat ggctttcata
     6781 tggctataac agattggaat gactcggttt gtaatgaaat ggaggatatg gtgaaagagg
     6841 gagtatcttc atttaaactg tatatggcgt ataaaggaag ccttcaagtt gatgatggtg
     6901 taatctttga agcattgaga aaagcagaag agataggagg gattattggt ttccattgtg
     6961 aaaatgggga cataatatgt gaacttgtgg ataaagcaaa gtcagaaaat aatttatctc
     7021 caaaatatca tcaattaact agaccagcta taatggaggc agaagctaca tcaagactta
     7081 tgaagatagc tgaagttgca aactctaaag tatatgtagt tcacttaagc tgtaaagaat
     7141 ccttagagga ggttttaaaa gctaagcaaa gaggtgtgga tgtaatagtt gaaacttgtc
     7201 ctcaatacct tctattaaat gatgaattat atgatttaga tggatttgaa agtgctaagt
     7261 atgtaatgtc accaccttta agaaataaag aaaataatga aatattatgg aatgctattt
     7321 tagataatca aatagacact ataggaacag accattgttc ttttaattat aagggacaga
     7381 aggaacttgg gataaacgat ttcagtaaga taccaaatgg ttctccaggt gtagaacata
     7441 ggatgagtct tttatacaca tatggagtct gtaaaaataa aatatctatc aacaagatgg
     7501 tagaagtaac atcaactaat ccagcaaagt tgtttggaat gtatcctaat aaaggaacta
     7561 tagaaatagg cagtgatgca gatatattag tcttaaatcc aaacaaaaaa tccaaaatag
     7621 aagcaaaaaa acaattacaa aatgtagatt atacacctta tgaagggtat gaagtggatt
     7681 gtcaaataga acatgtttat ttaagaggaa aagaagtagt tagagatgga gaattaatct
     7741 gtaatactcc aagtgggaga tatataaata ggcgtctaac aaagggggct agagaatggt
     7801 agaatttata ttaaatggag agaaagttgt tgcaaaagaa ggcaaaaaac ttttagactt
     7861 ccttagagaa gatatgaata taacttcagt taaaaatgga tgttcagaag gtgcttgtgg
     7921 aacatgtatg gttataatag atggtaaagc tactaaagca tgtgtattta aaactgataa
     7981 attagttggg aaaaacataa caactataga gggattatca gagagagaaa gagatgtttt
     8041 tgcatattct tttgctagtc aaggagctgt acaatgtgga ttttgtattc caggtatggt
     8101 aattagttca aaagcactta tagacgttaa taataatcct actgaagatg atataaagaa
     8161 agctttaaaa ggtaatatat gtagatgtac agggtatgta aaaataatta aagctgtcga
     8221 tttagcagca aagattttta gagaaaatat agatgtgcca aaagtaaact gtaaaggtct
     8281 agtaggtgaa aatcttccta gagttgatgc agttggcaaa gcacttggat attctgaata
     8341 tgtagatgat atgagaattg agggtatgat ttatggctca gcagttagag ctaagtatcc
     8401 tagagcttta gttaaaaaaa tagatataga agaagcaaaa gcttatccag gagttgttgc
     8461 agttctaaca gctaaagata ttccaggaac tataaaggta ggacacttaa agaaggattg
     8521 ggatacttta ataccagaag gtgaaataac tagatactta ggagatggaa tagttttagt
     8581 agcagcagaa actagagaag cgttagaaga ggccaaaaag ctagttaaga tagattatga
     8641 ggaattaaca ccattaagta ctacagcaga tgcacttaga gaagatgctc caaagataca
     8701 tgagacaggg aatatacttg ttaaggaaca tttagtaaga ggaaacgcta aagaaaagat
     8761 agaaaattca aaatatgttg taactaaaag atatactaca cctgctacag aacacgcatt
     8821 tttagagcct gaatgtgcag tagctggtcc ttatgaagag gatggagtaa taatctattc
     8881 aacagaccaa ggggtgtttg ccactcaaca tgaatgtgca gatatgttag ggttaccata
     8941 tgagaaggta agagttataa acaaaatggt aggaggaggg tttggtggaa aagaagacat
     9001 gagtgttcaa caccatgcag ccttacttgc ataccataca aagagatttg taaaagtaca
     9061 gttaacaaga aaagaaagta ttattgttca tccaaaacga catgccacag aaatggaatt
     9121 tacgacagca tgtgatgaaa atggatactt aacaggtatg aaggcaacga taatatctga
     9181 cacaggtgca tatgcctctc ttggaggacc agtgctacaa agactgtgta ctcatgcagc
     9241 aggaccatac aattatcaag atattgatat aacaggaaca gcagtatata ctaataaccc
     9301 tcctggagga gcatttagag gatttggagt tacacagagt tgttttgcaa ctgaatgtaa
     9361 tctaaattta cttgctgaaa tggttggaat atctccttgg gagataagat ataaaaatgc
     9421 aataagacct gggcaagttt taccaaatgg tcaatttgca gatgaaggaa cagcaatggc
     9481 agagacacta gaagctgtaa aagaagagta tgaaaagcat ccacgtgcag gtatagcttg
     9541 tgctatgaaa aatagtgggg ttggagttgg tatacctgat gttggaagat gtagattggt
     9601 gataaaagat ggcaaagttc acataagaac aagtgcttct tgtataggtc aagggcttgg
     9661 tactgttatg actcaagtag tttgtgaaac tgctaaccta cttcctgaaa atatagtgca
     9721 tgaagttcca gatactcatt taacaccaga ctctggtaat actacggctt caagacagac
     9781 agtatttacg ggagaagcta ctaaggttgc atcaaataag ttaaaagaag ctttagactc
     9841 tggcaaaact ttacttgatt tagagggaga agagttttat ggagaatatg aaagtattac
     9901 agataaaatg ggttgtgaca aagaaaatcc agtaagtcat gttgcttatg gatatgcaac
     9961 acaagttgta attctggatg aaaatggaaa actagaaaaa gtagtagcag cacatgatgt
    10021 tggaagagct ataaatccaa tcagtttaga aggtcaaata gaaggtggag tagttatggg
    10081 tcttggatat gctctaaccg aagattaccc agtagtcaac tctgttccta cagctaagtt
    10141 tggtacatta ggtttattta aatctacaga tataccagaa atacaagctt taatagttga
    10201 aaagaacaaa gatttattgg cttatggggc aaaaggtgta ggagaaattt gtacagttcc
    10261 tactgcacca gcagtacaaa atgcctatta tgtatttgat aaagaattta gaactgagct
    10321 accactacaa aatactccat atagtaaaaa aaagtaacaa aaaaaagaaa tattaaataa
    10381 aaaaatagat gaaattgtaa ataaaaaaaa cccttttgca taaggtatat tttaaatgat
    10441 agaatataca tatacaggag ggtttttctt ttataaaata agtttaataa aattgagagg
    10501 tgagcagaat gaattttaat aatagtctag aattaactca gtctcagaag ctaataatga
    10561 ctacacaact taagcaatca ttatcaatat taaatatgag taagttagag ttagaagaag
    10621 agataaaaag agaagcagag aataacccat tagttgaagt cgagaaaagt ggggagataa
    10681 attgggaaga gtatataaaa gacatggata ggtcaagacg tttagataga acagagataa
    10741 gctataatcc tgataatgaa gttaatctag aaaatttagt taaatattcg tcaaatttat
    10801 atgaagattt aaaatttcag ataagcctgt ataaacttac agacaaagaa ttggaagtct
    10861 gtgagtatat aattgatagt ttagatgagg atggatattt aagaactgag gaaaaagtaa
    10921 ttgttgatac cttaaagata gatgaagaac tttttgaaaa atgtttaatt agtgttcagc
    10981 agttggaacc tagtggagta ggggcaagaa gtctttcaga atgtctgatg atacaaatgg
    11041 ctagtttagg aatatataat gaaattttag aggaaatcgt tacaaaagac ttaaatttaa
    11101 ttgcaaataa taaatataaa gagataagta aaaagtacaa tatgtcatta caaaaatgtg
    11161 ttgaactaat aaacataatt aagacattag accccaaacc aggaagaact tgttcagtag
    11221 agaaaagtgt atacattcaa cctgatgtaa cagtagaaaa aattgatgat gaatttattg
    11281 tatatttaaa tgagaaagat tcttatcaaa taagaatcaa tagttattat aaagacatat
    11341 taaaaaattc acagtctgat gaaagtgcaa aagaatttat aaaagaaaga ctaaattcag
    11401 caacaggact tatgaaaaat atagagagta ggaaaactac agtacttaag attgcagaag
    11461 agatagtaaa agctcaagat gaatttttga gaaaagggac aaaatatata aaacctttga
    11521 aaatgaaaga catagcagaa aaattagaat ttcatgaatc tactataagt agaggtgtaa
    11581 atggtaaata tatgctaaca ccttttggcg tatatgaatt taggtacttt ttcagtagcg
    11641 ccattgagac tgagaataat gaaatggcat ctagtacaag cataaaaaaa attataaagg
    11701 aaacaataaa agacgaaaat aaaaagaaac ctttaagtga tgaccatata tctaagttat
    11761 taaaagaaaa aggaatcaat gttgcaagaa ggacagttgc caaatatcgt gaagaattag
    11821 gaatcccatc ttcaagtaag agaaaagaat actaataagt aaaagacaaa tatcagtatg
    11881 gtaaggggaa aaggctaatt aagagatgaa tgtagattgg gctaaaaatt ttataaagta
    11941 aaataataga atatggaaaa gtattaaaat gctataaggt attaaaaaac tggggaacat
    12001 taaaacatta agatagcaaa gagcataaaa aactaaagaa gattaaaaca ttaaagaaca
    12061 ttagagcttt gaggaatatt agaactttaa agaatattaa aatttataaa atataaaaat
    12121 actaaaaaga attgaaaaac tggggaacat taaaatattg taaaatgcta aaaaactaga
    12181 aaacataatt aaataagtgc ttataaagaa tgattaaatt aaataagtgt ttgtaaagaa
    12241 taattagata ttagaaaaag aagaatacct agataaataa actattatta aatttaataa
    12301 tc
//
LOCUS       DAMJXI010000093        12133 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.098, whole genome shotgun sequence.
ACCESSION   DAMJXI010000093 DAMJXI010000000
VERSION     DAMJXI010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12133
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.098"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            222..1103
                     /locus_tag="PC465_003338"
     CDS             222..1103
                     /locus_tag="PC465_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HDF2650615.1"
                     /translation="MVKKRKKKTVTLTILVVIVIGIFSMAWADMSRKKEMKETQERLK
                     AERLEKERIEKEKNEPIIGAKKEAVKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDD
                     GPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDY
                     KKLYPNRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLK
                     EKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALD
                     QIITYFKDNGYQFKILI"
     gene            complement(1164..2372)
                     /locus_tag="PC465_003339"
     CDS             complement(1164..2372)
                     /locus_tag="PC465_003339"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HDF2650616.1"
                     /translation="MKSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGL
                     DPSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVL
                     ANAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRY
                     EGQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIM
                     MPLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVN
                     KIESQLKEGSVNPRDIKMNLAREIVTLYHGEESAKEAEERFKSVFQKGQIPEDIQTIQ
                     VKEDGFDLIEVLVSNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGK
                     KKFVKIELVK"
     misc_binding    complement(2445..2697)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(2849..3838)
                     /locus_tag="PC465_003340"
     CDS             complement(2849..3838)
                     /locus_tag="PC465_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2232 domain-containing protein"
                     /protein_id="HDF2650617.1"
                     /translation="MIYGGSVLNTTKKLTEAALLSSLFIVVTIIAVSTGFGYAIYLDF
                     IVPVFFCIICLKCDLKYTILSGITSLLIISLVLGNLGTAIWASQSVLLGIMCGYLINK
                     PTMVMDDLVYGSVFGVIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGYTNFIYYLM
                     IALFPFGMVFCIYLLSLILGNKLHILDSNSLKKFLIFKNFRNLNQFLCCSKKAFYICV
                     SYLAIFEVLKLLNVKVDSVYLKTIFISITYISVYFIIRDSCMSLQNFIIAKFRKLLYA
                     RILFLIIILLLFFIFDVTVISLIIINAFLNKKINIRLSQSNIVNKQINLLIEK"
     gene            3990..4430
                     /locus_tag="PC465_003341"
     CDS             3990..4430
                     /locus_tag="PC465_003341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2650618.1"
                     /translation="MFKIKHFNDLSLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKS
                     SYHIFLKENGLICAYARIIPKEYSSYNDVSIGRVLVLSSHRRKGLAKQMMDCAIDFIK
                     VNLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL"
     gene            4757..4984
                     /locus_tag="PC465_003342"
     CDS             4757..4984
                     /locus_tag="PC465_003342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2650619.1"
                     /translation="MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRK
                     GPKNNLTVYKIRGSKIALRQEESSLILVSDI"
     gene            5010..7130
                     /gene="feoB"
                     /locus_tag="PC465_003343"
     CDS             5010..7130
                     /gene="feoB"
                     /locus_tag="PC465_003343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDF2650620.1"
                     /translation="MGLTHNSTKMSSLKDMFDIDNKEDQFVIALAGNPNTGKSTVFNH
                     LTGLRQHTGNWPGKTVATARGNFKYKNTEYALIDLPGTYSLFALSQEEIVARDFICFG
                     NPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEARKKGITIDKKLLEDSLG
                     IPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIENVVKSIQPELDNIIP
                     GINSRWLGLRLIDGDESIFESMSNYIDKDSIDAINEVKKKIPDNINKQKIRDEFTKIN
                     YDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYP
                     STLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLF
                     TLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLI
                     AILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVS
                     YTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITW
                     IFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLAT
                     GSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTAL
                     GFLMPTILAFVVCFLTTTVYNLFI"
     gene            complement(7263..8081)
                     /locus_tag="PC465_003344"
     CDS             complement(7263..8081)
                     /locus_tag="PC465_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2650621.1"
                     /translation="MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYY
                     SVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKIS
                     SKMQNRINITVEGISKMNSEEIYISKKFEEYLVLSSDLSNMSNSDFMMELIDFTNYCK
                     SKNLYQGYELGVIVSNENIKNGDYLSISSFYLKIDKKIKDKKLYVKPEGMYACIKHIG
                     KYEDSYKSYEKLKKYIYENEYKIIGNSYEESILDFFCESNEDNYMTEISIQVSR"
     gene            8288..8572
                     /locus_tag="PC465_003345"
     CDS             8288..8572
                     /locus_tag="PC465_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650622.1"
                     /translation="MLVRVKIVIGATIRYLIKHKVNYCNKKSLDKLELKYGNIDREKA
                     VKLEIFYQYLIELEYIEMSLLIRRLDTAITSLALVSIITIASYYLIRKNV"
     repeat_region   8740..9231
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=8807..8835
                     /rpt_unit_seq="atttacattccatatagttaatataaaac"
     gene            complement(9890..11983)
                     /locus_tag="PC465_003346"
     CDS             complement(9890..11983)
                     /locus_tag="PC465_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2650623.1"
                     /translation="MNKHNFEVILNQLQINIYVTNIHTNEIIFMNKKMKEEYNILDPE
                     GKVCWQVLYPEKNSTCSFCKVLELLKNDKKGVLIKWYEKCNKLNRVFENYDSLITWQD
                     GTVVHMHQSIDIANSTSLNKPIKINEFHEISNNKEEKGVFNFSRDNFDYNSTLLYDAL
                     IRGTDEYIYICNMKTGVFRYSPSQVELFDLPGEIVKNPLVYWKKIVHPEDWNRFYKSN
                     TEIGKNQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGEPSIFAGIMTQLGKQNKID
                     SLTQLLNYHEFMSVFEDKISNPMIEKLCIVLLDIDDFKNVNEMYDRDFGDNIIKTLAQ
                     SVQSILPDNAELYKLDGDEMGILVDNVEENEILTLYNQIQNMIIHLQLWRKYGLNITI
                     SAGCVIYPKHGDTVKELYKCASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLK
                     ASINDDFRGFSLRFQPQVDTESHKIIGVEVLLRWTNDKCKAISPLEFIPILEENDMIN
                     IVGAWVLRMALRTFRKWIDYYPFFKVSVNVSAVQILEDTFIEDIVKIIDDENFPYQNL
                     VLELTESHTVQNMSILQFKFKALQDLGIYIAMDDFGTGYSSLEVLKFSPIDIVKIDRV
                     FVKDILKSKFDATFIHFIVAICHDVGIKVCLEGVETQEEYDLVKQIKPDYIQGYLFGK
                     PQTATEIFDLLKLDN"
BASE COUNT         4299 a         1782 c         1440 g         4612 t
ORIGIN      
        1 ttttaataaa tttttatatt ttttatattt ttttacctat actaaatttt tttatagata
       61 tttttaatat atatgatact ttaatattat gcaaataatg tcatataagt tacactttag
      121 ttatcttagt tacaactttg tcggtttact ttttctactt tcttcgatat aattataata
      181 tatttttgat acaattcgac aaaaggggga atgctgtaat tatggtaaaa aaaagaaaaa
      241 agaaaactgt tacacttact atacttgttg taatagttat tggtattttt tctatggcat
      301 gggcggacat gtctagaaaa aaagaaatga aagaaactca agaaagactt aaagctgaaa
      361 gattagaaaa agaaagaatt gaaaaagaaa aaaatgaacc tattattggt gcaaaaaaag
      421 aagctgtaaa agaatatgga tatgacgcaa aaatagtttg ggacaaactt aacaaatacg
      481 actattcaaa caatggagaa aagatagtct ttcttacatt tgatgatgga ccatctacta
      541 ctaatactcc acaagttcta gatatcttga aaagacatgg tgttagagga actttcttta
      601 ttaagggtga ttctcttgaa agaaaaggag ctaatgaaat tttaaaaaga acatttgacg
      661 aaggaaatgc aatagcccat cactcttata ctcatgacta taaaaaacta tatcctaaca
      721 gaagcctaaa tctcgataca ttcgtaaatg aacttaacaa aactgatgaa gctatgaaaa
      781 aagtcttagg aaagaatttt tcctcaaatg tagttagatg cccaggcggg tatatgtcat
      841 ggaaaaatat ggaacctcta ggaaactact taaaagagaa aaacatggca tcaattgatt
      901 ggaacgcttt aaatgctgat gcagaaggta aaaagaaaaa tgcacaagaa ttatttgaac
      961 atgcaaagaa atcttctgaa ggcaaagaaa tggttgttct tttaatgcat gatacttatg
     1021 gaaaacaaga aacagtaaat gcattggacc aaattataac atattttaaa gacaatggtt
     1081 atcaatttaa aattttaata taataaaaaa gcaagtttat tgaatgtaca ttttatactc
     1141 aatagacttg cttttacttt actctatttt actagctcga tttttacaaa ttttttcttt
     1201 cctatttgaa caactaattc actctctttt acaatagtgc ttaaatcctc tactttttca
     1261 ccatttacct ttactccacc ttgagaagct aatcttctaa cttcactctt actcttaaca
     1321 atctcattag aaactagtac ttcgattaag tcaaatccat cttccttaac ttgaattgtt
     1381 tgtatatctt caggtatttg acctttttgg aatacagatt taaatctttc ttcagcttct
     1441 ttagcagatt cttctccatg gtataatgtt actatttctc ttgctaagtt catctttata
     1501 tctcttggat ttactgaacc ctctttcaac tgagattcta ttttattaac ttcatcagga
     1561 tgaacatctg tcactaaatt gtagtattta attataagtt catcaggaat ttccatagat
     1621 ttttggtaca ttattcccgc ttcttcatct attccaatat agttacctaa actcttactc
     1681 attttttctt taccatctaa tccttctatt aaaggcatca ttattactat ttgagactcc
     1741 ataccaaatt ctctttgtaa tgatcttccc attagtaaat tgaatctttg gtcagttcca
     1801 ccaagttcta tatcagcttc taatgctata gagtcatatg cttgcattaa tgggtagaag
     1861 aactcatgta ctgatattgg catttgtcct tcatatctct ttttaaaatc ttctctttct
     1921 aacattctcg caacagtaat agttgctgct aattttatta catcttcaaa atttaactta
     1981 gctaaccact cgctattaaa tcttacaata gttttttctt tatctaaaac tttgaaaatt
     2041 tgttcttcat aagtttttgc atttgcaaga acttgctctg ttgttaaagc ttttctagct
     2101 ttagattttc cagttgggtc tccaattttt cctgtaaaat ctccaattat tattactatt
     2161 tgatgaccta aatcttgtaa ttgtttcatc tttctaagaa ctactgtatg ccctaaatgt
     2221 atatctggag cacttgggtc tagacctaat tttactatca taggctttcc ttctttttct
     2281 gatttaataa gcttttccct taactctttc tcatctatta aatcatctac acctttcata
     2341 attattcgca tttgctcgtc tatcgatttc atttttcatt cctcctaaaa tatttatata
     2401 atctataatt tttattttta taataaaaaa agctttcatc ctcttaaaag gacgaaagca
     2461 ttgcttacgt gttaccacct tagttcatca atatctcacg atattaatct cttagagtac
     2521 aattacatat actcgtgtac tataacgtgt actaatccga tatctcttaa tggttgttat
     2581 ctttcagaga tagtgctctg agatgtattc aaactaaatc aatttattcc atttcaccaa
     2641 actggaactc tctgttaaat aaaatctagc cctacttctt ctcttcatag catttatata
     2701 ttcagattat ttcatcaatt acaagaaatt tttcttaact tactcataat atattattat
     2761 ttttatattt tgtcaacctt ttttattatt atatacatgt ttttttacat tatactactt
     2821 ttttatattt tttaccaata cccaaaattt atttttcaat caaaagattt atttgtttat
     2881 tgactatatt actctgactc aatcttatat ttattttctt atttaaaaat gcgtttataa
     2941 ttattaaact aataactgtt acatcaaata taaaaaacag caataaaatt attatcaaaa
     3001 ataaaattct agcatataat aattttctaa acttagctat tataaagttt tgtagtgaca
     3061 tacatgagtc tctaatgata aaatagacac ttatataggt tattgatata aagattgttt
     3121 ttaaataaac agaatcaact ttaacattca acagttttag aacttcaaaa atggctagat
     3181 aagaaacaca tatgtaaaaa gctttttttg agcaacataa aaattggttt aaatttctaa
     3241 aattcttaaa tattaaaaat ttttttaaag aattagaatc taaaatatgc aatttattcc
     3301 ctaaaattaa acttaataaa tatatgcaaa acaccatacc aaaaggaaac aatgctatca
     3361 ttaaataata aataaaattt gtatacccat taaaataaat ccatttgcta tatccttgaa
     3421 attctttcat aaaactataa cctattaatg ttgaagcata tatatcaatg aaaaccatta
     3481 caataacccc aaatactgaa ccatatacta aatcatccat aaccattgta ggcttattta
     3541 ttagatagcc acacattata ccaagtaata cactctgact tgcccaaata gcagttccta
     3601 gatttccaag taccagagaa attattaaaa gcgaagtaat tccagataaa atggtatact
     3661 ttaaatcaca tttcaagcag attatacaaa aaaatactgg cactataaaa tctaagtaaa
     3721 tagcatatcc aaatccagta ctcacagcta taattgttac tactatgaat aaagatgaca
     3781 ataaagctgc ttcagttaat tttttagtag tattcaaaac actgcctcca taaatcataa
     3841 attttctaac taaagttttg tttttaatat agtatatcac tttttaaaaa tatttttaat
     3901 aaatataaat tttaataaag gtatttatgt taaaaatggt ataatgtatc ttaatattca
     3961 gttttttaag atgctaggag gtaattacta tgtttaaaat taaacacttt aatgatttga
     4021 gtttagatga attttatgaa atagcaaaat caagatatga ggtatttgct tgtgaacaga
     4081 agatattttc attaaacgat tatgatgata tagataaaag ctcttatcac atatttttaa
     4141 aagaaaatgg attgatttgt gcttacgcta gaataattcc taaagaatac agctcttata
     4201 atgatgtttc cattggtaga gttttagttc tttctagtca tagaagaaaa ggattagcaa
     4261 aacaaatgat ggattgtgct atagatttta taaaagttaa cttacacgaa aataatataa
     4321 ccttatcagc acaaacttat ataaagaacc tttacttatc ttgtggtttt aaagaaatct
     4381 cagaagtata cgacgaagca ggtattgaac atattaaaat gagattatag tgttgacaag
     4441 ctaatattgt taatatataa tttaagtata aattaaatat tgaattgata tttaggtatt
     4501 tgaaaatacc ttacatagag tcagaaggct tttgctttct gactttttta ttatcaaaat
     4561 tcaataatta tatggattca aagtgttaat ttttattcta tattctactt tccccaaaag
     4621 taagaattat acccaacttt gtatgatagg catcttgcct atcttttttt tgtaaaagta
     4681 acaaggtaat aatataatgc atagtttaaa ataagaagat tagcccaggc taaatttcaa
     4741 gcatggaggt gctattatga aaaaccttaa cgatattcaa gtgaaaaaaa ctgtcaaagt
     4801 tgaagatata ttatctagtg gtaatttaag agaaagaatg ttagcgcttg gtcttactag
     4861 aggagctgtt atagatgtag ttagaaaagg tccaaaaaat aatttaactg tctataaaat
     4921 cagaggtagc aagatagctc tacgacaaga agaaagtagc ttaatattag tttctgacat
     4981 ttaaaaattt ctagcaggag gatattaata tggggttgac acataactca actaaaatga
     5041 gttctttaaa agacatgttt gatatagaca ataaggaaga ccagtttgta attgcattgg
     5101 ctggcaatcc aaatacaggt aaaagtactg tatttaatca tcttacaggg cttagacagc
     5161 atactggaaa ctggccagga aaaactgtag ctacagctcg tggtaatttt aaatataaaa
     5221 ataccgaata tgcattaata gatttaccag gaacatattc tttatttgcc ttatcacaag
     5281 aagaaattgt agctcgtgat tttatatgtt ttggtaatcc agatgcagta atagtagtat
     5341 gtgatgctac atgtcttgaa agaaatttaa atttagtatt tcaagtgatg gaacttacag
     5401 ataaagttat tttgtgtatt aatttaatag atgaagctag aaaaaaaggc attactattg
     5461 ataaaaaact tttagaggat tctcttggta ttccagttat tttaactgct gcaagaaatg
     5521 gctctggtat ggatgaacta ttggatactt taaatgatgt atcttttgac aaatacaaat
     5581 taaataataa acctgttaga tacaatgaaa atatagagaa tgtggtaaaa tcaattcaac
     5641 cagaattgga taatattata ccaggtataa attctagatg gttgggactt agacttattg
     5701 atggcgatga aagtatattt gaatctatga gtaattatat agacaaagat tctatagatg
     5761 ctattaatga agtaaagaaa aagattccag acaatataaa taaacagaaa ataagagatg
     5821 agtttactaa aatcaactat gattatgcta aaaaactgag tgatgagtgt tgttctaatg
     5881 ttgctaaaaa atcaactgat agagaagaaa aagtagataa aatattaaca tctaaaatat
     5941 ttgggcttcc aataatgctc ttattattag gtactatatt gtggattact atagaaggag
     6001 ctaactatcc atccacttta ttatctaatt tattactcgg atttgagcca agtatttcgg
     6061 gtatattaaa tagtattaat tgtccatcat ggttaaatga tatgttggtt ttaggattat
     6121 acagaacatt agcatgggta atctctgtaa tgctacctcc tatggcaata ttttttccat
     6181 tatttacctt acttgaggat tttggatatt tgccaagagt tgcatttaac ttagaccacc
     6241 tatttaaaaa agcttgtgca catggaaaac agtgtttgac tatgtgtatg ggatttggat
     6301 gtaatgcagc tggagttatt ggttgtagga taattgactc tccaagggaa agacttatag
     6361 ctatacttac aaacaacttt gttccttgta atggtcgttt tcctactttg atagctatat
     6421 ctacaatatt ttttagctca gttataacca actctttcgt atcaagtgta gcaactgcac
     6481 tttgcataac tttactgata attctaggtg ttataataac attgttggtt tcttatactc
     6541 tttctaaaac gctattaaaa ggagttccgt ctacatttac attagaactt cctccttata
     6601 gagttcctca aataggaaga actttatata cctctataat agatagaaca atatttgttt
     6661 taggaagggc tgtaatggta gccatacctg ctggtgtcat aacttggata tttgcaaata
     6721 tatatatagg agatttaagt atattatcac atgttgcaaa ctttttagac cctttagcta
     6781 aattaattgg tcttgatggt tttatattac ttgcttttat tcttggattc ccagcaaatg
     6841 agatagttgt acctatactt ttaatggctt acctagcaac tggttctatg atagaattag
     6901 atagctttag tgctttaggt caagttctta gagaacatgg atggacttat ttgacagctt
     6961 taaatgttat gctgttcagt ttactgcatt ggccttgtgc aacaacactt ttaacaataa
     7021 aaaaagaaac tggtagttta aaatggactg ccttaggatt cttaatgcct actatacttg
     7081 cttttgttgt ttgtttttta acaactacag tttacaattt atttatataa ttagtattaa
     7141 ctgacattag acatatatta gagaaactat ttaaaaattt atatacttta ttataaagca
     7201 tagagatata ttcaatgata agtaaaatta cttaacattt gaatatatct ctattttaat
     7261 tcttatctgg atacttggat tgaaatttca gtcatataat tatcttcatt actttcacaa
     7321 aaaaagtcaa gtatactctc ctcatacgaa tttccaataa ttttatattc attttcatat
     7381 atatattttt tcaatttttc gtaagattta tatgaatcct catattttcc aatatgtttt
     7441 atgcaagcat acattccttc tggctttaca tatagctttt tatcctttat ttttttatct
     7501 atcttcaaat aaaaacttga tatacttaaa tagtccccat tttttatatt ttcattactt
     7561 actattactc ccaactcata tccttgatac aaatttttcg atttacaata attggtgaaa
     7621 tctattaatt ccatcataaa atcactatta ctcatattac tcaaatcgct tgatagaact
     7681 aaatattctt caaacttttt ggatatataa atttcttcac tattcatttt agaaattcct
     7741 tcaactgtta tatttattct attttgcatc ttagaactta tctttcttag tttttttatt
     7801 ttttctctta tctttttttc ttcttcttta agcattttca cacaaagctg gggagttcta
     7861 ttttgtatat actcttttat ttcctctaaa ctcattccta tttctctcaa tgattgtaat
     7921 atatcaagtg tatcatattg ataaactgag taatatctat aattattttt atctttatat
     7981 tcaggagaaa aaatacctat tttgtcatag aaaattaatg tctgcttaga tataccacac
     8041 aatttagcaa attcacctgt tgtaaaatac tgtttttcca agggttatac actccttttc
     8101 tttttgttgt ctatatagtt actatattct ttattattta ctaaatcaag tagttattat
     8161 tttagaaaat caatatggtt ttgattttaa agcttaaatg tcagttagat gtcagttata
     8221 aatattttat ccattcccat cataaaaaag atatcccctc ttaacttttg gatggaatat
     8281 tatatttata cttgttagag tgaaaattgt aataggtgct acaataagat atttaattaa
     8341 acataaagtt aattattgta ataaaaaatc tttagataaa ttagagttaa agtatggaaa
     8401 tatagataga gaaaaagctg ttaaactaga aatattttat cagtatttaa tagaacttga
     8461 atatatagaa atgagtttat taataagaag attagatact gcaataacat cattagcatt
     8521 agtatctatt ataacaatag catcatatta tttaatcaga aaaaatgtgt aattatgtaa
     8581 gctatttata ataaaacact gataaaatta ataataaaaa ggtaatagga tttctatact
     8641 acctttttgt ttttataata tagtgtaatt ttattatatt tttgtatgct aatgtaacta
     8701 gataatcata agataacaca ttaaaagaaa attatgaaaa cttacattct gtatagttaa
     8761 tataaaacat aagtaatata aatttatgta aagcaacaaa agatagattt acattccata
     8821 tagttaatat aaaacgaagt ttacattttt attttagaat ataagtcgtt gtaatttaca
     8881 ttccatatag ttaatataaa accttagaga aagcgaaaac gtaccattaa aatcaaatat
     8941 ttacattcca tatagttaat ataaaacttg tagttaatat tataattcca actcctataa
     9001 gtataattta cattccatat agttaatata aaactattgc ttaaactttt aagacaaggt
     9061 ggagcttaaa aatttacatt ccatatagtt aatataaaac tatccaacca attctatatt
     9121 tatcattcca agaacgattt acattccata tagttaatat aaaactttcc tctaaagtcc
     9181 aaacaccctc tagctttccc gtatttacat tccatatagt taatataaaa caccaaaata
     9241 aacttagtat tttcaacact tacacgtata caactctcct aaatttgcag tgaacgagca
     9301 atagtgcaat tgataacgct tatcatgcac tctcaacgcc ttatatttca actgttacgc
     9361 caaatttttt cacaaatatc gctcactgca aaattcctat aattttatta tatcataaat
     9421 atattacttt tgaatattga taccaattta taccataata aaagcaaaaa aacgtaatct
     9481 atctacatta gatttaaatt ctataactta aagtttttta cataatattt atgcttgttt
     9541 aatcaatcta atatatcatt cttgtatatt gcttttaata gtcttttttc ttaaataaat
     9601 atctatctga acaagcatag tttaattaaa aacttttgta ttcccttaaa actgtatcta
     9661 cctcttatta ttttatttat gatatattat ttttaatcta aaaatagata tctattttta
     9721 ttatggttat ccctttttaa aatactttaa tcatatacta ttcccaattt aacatccatt
     9781 gaaatgctat tttcttatat tgcaatttat aattgatata tcttcaatat aataatttaa
     9841 tgtatttttg attttaaagc ttttcagtga tattattgat aaattagaat taattatcta
     9901 gctttaaaag gtcaaagatt tctgttgctg tctgcggttt tccaaataaa tatccttgta
     9961 tgtaatctgg ctttatttgt ttaactaaat catactcttc ttgtgtttct acaccttcta
    10021 aacatacttt tattcctaca tcatgacaaa ttgcaacaat aaaatgtata aatgtagcat
    10081 caaacttact ctttaatata tctttaacaa atactctatc aattttcact atatctattg
    10141 gagaaaattt taaaacttct agagacgagt atccagtacc aaaatcatcc atagcaatat
    10201 aaattcctaa atcttgtaaa gccttaaatt taaactgtaa aatactcata ttttgtactg
    10261 tatgactttc tgtcaattct aaaacaagat tttgataagg aaaattttca tcatctataa
    10321 tttttactat atcttcaata aatgtgtctt ctaatatttg aacagctgaa acgtttacac
    10381 tcactttaaa aaaaggatag taatcaatcc atttcctaaa agtacgtaat gccattcgaa
    10441 gcacccaagc ccctacaata tttatcatat cattttcttc taatattgga ataaattcca
    10501 aaggagaaat tgctttgcat ttgtcattag tccaccttaa aagaacttct acacctatta
    10561 ttttatgact ttctgtatct acttgtggct ggaatcgaag actaaacccc ctaaaatcat
    10621 cattaattga tgcctttaaa tcccgcatca tttctaatga atacatttta ttttttaata
    10681 tttcttggga gaaaaaaaca agcctgtttt taccatgctc tttcgcatat tgtaaagagt
    10741 aactagcaca cttataaagt tcttttactg tatctccatg ttttggatat attacacaac
    10801 cagcagaaat tgttatattt aatccatatt ttctccatag ttgaaggtgt ataatcatat
    10861 tctgtatttg attatataga gttagaattt cattttcttc aacattatca acaagaatgc
    10921 ccatttcgtc cccatcaagt ttataaagtt cagcattatc tggtaaaata gattgtacag
    10981 actgtgctag tgtttttatt atattatctc caaaatccct atcatacatc tcattaacat
    11041 ttttaaaatc gtcaatatct aataatacta tgcataattt ttcaatcata ggatttgaaa
    11101 ttttatcttc aaatacactc ataaattcat gataattcag taactgtgtc aatgaatcaa
    11161 tcttattttg tttacctaat tgcgtcatta ttcctgcaaa aatacttggc tctccaaatt
    11221 catcacgcat tagttgacct ctacatctta accatatata ttctccacta cgatttttag
    11281 ccctaaattc cactgtatga taatccatct ggtttttacc tatttcagtg tttgacttat
    11341 aaaaacgatt ccagtcttct ggatgtacaa tttttttcca gtaaacaagc ggatttttaa
    11401 caatttctcc tggtaagtca aataattcaa cttgtgatgg tgaatatcga aatacgcctg
    11461 ttttcatatt gcaaatgtat atatattcat ctgtacctct aatcaaagca tcgtaaagca
    11521 atgtagaatt ataatcaaaa ttgtctcttg aaaaattaaa aactcctttt tcttctttat
    11581 tatttgatat ttcatgaaat tcattaatct taattggttt atttaagctt gttgagtttg
    11641 caatatctat tgattgatgc atatgaacaa ctgtgccatc ttgccatgta attaaactat
    11701 cataattttc aaaaacacga tttaacttat tacatttttc ataccacttt attaatactc
    11761 cttttttatc attctttaat aattctaaaa ctttacaaaa actacaagta gaattttttt
    11821 caggatataa tacttgccaa caaacttttc cttctggatc taaaatatta tattcttctt
    11881 tcattttttt gttcataaaa ataatttcat tagtatgaat atttgtaaca tatatattaa
    11941 tctgtagttg atttaatata acttcaaaat tatgtttgtt catatactta tctcctccat
    12001 agttactgct ctttataaca acattgttaa aattattctt tttagaagat ttacttataa
    12061 cttatacata tacactaaat accttaattt aattagaaag tttattactt catattttaa
    12121 attataattg ata
//
LOCUS       DAMJXI010000094        12124 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.099, whole genome shotgun sequence.
ACCESSION   DAMJXI010000094 DAMJXI010000000
VERSION     DAMJXI010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12124
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.099"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(50..2161)
                     /locus_tag="PC465_003347"
     CDS             complement(50..2161)
                     /locus_tag="PC465_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2650624.1"
                     /translation="MTINKLYSKLRAYNWKNYTTLFFCIILSVVLVTSYALIYFSPTI
                     QNILPTGGDSRKQATMIFSVAILGCTVFTTYASSLFLKFKSKEIGIFMALGTDKKKLK
                     KLLFSEILLISVVCCFLGLILSIPVSFGIWKIFQLVIIDTREMTYHFGTQGFIYGFIF
                     SVFVTLCIFILSVKFINRTNIIDILNDQRISEPIQDVKDWYGILGIIFIILGIFLGYL
                     VPSLTINKLNYRLPSVWSFTYLLSLIGIYMIMTYIVVHAKRGKHPEKYYKNIISTSMM
                     RFMGRQTVKNMCVISFLIAGALFAVFYVPNMVTGIYDTLKNNPIDYTFTYNQRDKQVS
                     KKDIEQLADKHNIKIQNYMEIPSIELIVDGVESIYHKDGTIEKVYMKKSSYDMFFNSK
                     DFSKLIGKPITIKNGEYLAVVNKGNENQDYKYTKFISSPVTEKEIPFRYAGKIIFNGS
                     FFQNRSMNAYVLNDEDYKSFTKDLSIKNYNNSILFNVDKDTYAFANDLKKEIIKRTSK
                     EMGMFSGYDEYVKKRYESTGRKYFMDEEYPSGEGHLKLDPNNNQLYLNWKYYPNFKIL
                     QSQDMIKNMAVFLMLFIYVAIICFTAVGIIAYTRGVTIAINHKQVFMDLNRLGANNDY
                     IKFCIRNQLKKVFSYPLIAGSFLIYLFNFMIMLNNDGRIVNSEVNALLINLGFIGICG
                     VYMYLIYLLTYKKFKKIIGIL"
     gene            complement(2151..2903)
                     /locus_tag="PC465_003348"
     CDS             complement(2151..2903)
                     /locus_tag="PC465_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2650625.1"
                     /translation="MLKVNQLCKSYKTGSKTYPVLKNISFEINKGEFVAIMGSSGSGK
                     TTLLNCISCFIPIDNGEIILGNNNIRNLKEKELSEVRNQQLGFVFQDFMLFDGLSVFE
                     NICVPQIIKGSQVLQMENRAINLCELFGIEHIRKKYPAEISGGEKQRTAVARALMNNP
                     DLILADEPTGNLDSKSCRTVIESFLKAKQELDATILMVTHDSFSASFCDRVIVLKDGI
                     IYKEVVKSNSRHKFLDELLEVLKEMGGAQDDN"
     gene            complement(4097..4273)
                     /locus_tag="PC465_003349"
     CDS             complement(4097..4273)
                     /locus_tag="PC465_003349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650626.1"
                     /translation="MFFTFIGVISAILLLCTIICGLWIKLNNRNNDSNSHFTFSILSI
                     AFSLLIVVAFLVRN"
     gene            complement(4377..4985)
                     /locus_tag="PC465_003350"
     CDS             complement(4377..4985)
                     /locus_tag="PC465_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2650627.1"
                     /translation="MKKLLRGKIMKADSTKEQLINATIQLLSSHRDVSSITAREIVAK
                     ANVNLAMINYYFKSKEELINISIKKFLKRHMDEYKATHDTKNLAPKQQLREILIAFFD
                     FIGEHSQFIKISVPYILIQEEIVYPFEILPLIKAHYENQNNKKTEAEYRTIAYQITSF
                     IQLLFLRSNAFFKYSGIDILNVEQRNGLIDFQLDLLLVDITK"
     gene            complement(5084..5908)
                     /locus_tag="PC465_003351"
     CDS             complement(5084..5908)
                     /locus_tag="PC465_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2650628.1"
                     /translation="MFKIGEVSKLTQISIRMLRYYDELGILKPAKTDKYTGHRLYSVE
                     QISILQRIVLLRDSKFSVAEIANIVHNWNDEFVIKELNRKKNEIQKEIKQEQQRINKI
                     DKFIEAINCDKDEIHYNVVFKKIPSYKIISLREIIPDYQSEGILWEKLSKFIKEEHIE
                     VSRQSNNNIAFYHDEEVKDNGVDIEVGMVVKKIGKNKSGFIYRETEEIDMMACTMVYG
                     PYENIAGAYESFCYWLDKNSDYQISGINRQIGHKGEHNEINPENYLTEIQIPLIKV"
     gene            complement(6086..6979)
                     /locus_tag="PC465_003352"
     CDS             complement(6086..6979)
                     /locus_tag="PC465_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2650629.1"
                     /translation="MQLYNTPFNTNKHLIYFFTFTLVLNWIFSLTPALLGITNTILGE
                     IIFYLAYTSPAIVGLFFISTIYPQSAKQDFIYRYLSFKEIRIKWILLTILFFALTFIT
                     SLIIGNYFNVKTSDIDWIHIAVFRPSKIAYMLLASFILSILSQEAGWRGYAIDKLLVR
                     FGFIGSSIILGLVCGIWYLGSYFTPNQIPYNLAQYSLFDAFLFIPNIVLLNFIINFVY
                     INTSRSILSAGLVHMMYYFFNIQLLLHYPIKLCVIAQYVQIIFGLIFLVYMISSNKFK
                     QKVNSEIEQIKSDDFEFELDW"
     gene            complement(7236..7673)
                     /locus_tag="PC465_003353"
     CDS             complement(7236..7673)
                     /locus_tag="PC465_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HDF2650630.1"
                     /translation="MKIHVEQGINCDDIEITIKCSALDNNIEKIISLLSTPLLDIKGK
                     KSGEIYKLNVYDILYFETVGNKTFAYYEDDVFEIDLKIYKLSKLLANTSFSRISKSMI
                     LNMDYIKSIKVISHNRMQATLKNNEKVIINRRYIKNIKEKLNI"
     gene            complement(7930..8079)
                     /locus_tag="PC465_003354"
     CDS             complement(7930..8079)
                     /locus_tag="PC465_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvrJ family protein"
                     /protein_id="HDF2650631.1"
                     /translation="MDDSLQLLITNVGFPIALSMYLLVRIEGKLNTLSNSIDTLSKNI
                     LIFKK"
     gene            complement(8092..8322)
                     /locus_tag="PC465_003355"
     CDS             complement(8092..8322)
                     /locus_tag="PC465_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HDF2650632.1"
                     /translation="MEIKKKLVMSFKNVKDKQVSFSIENPKDDLTEENIKSVMDLIVS
                     KNIFSVGGFDLASVVEAKVVETNTTPYDLVIE"
     gene            complement(9181..9402)
                     /locus_tag="PC465_003356"
     CDS             complement(9181..9402)
                     /locus_tag="PC465_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1659 domain-containing protein"
                     /protein_id="HDF2650633.1"
                     /translation="MEVVSTKNLSSIKLKLDAGFDDKGKAVVKSKSFANVKAEALNED
                     VYAVAEAIASLQENPIVDILKLDSTSLSK"
     gene            9982..10239
                     /locus_tag="PC465_003357"
     CDS             9982..10239
                     /locus_tag="PC465_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2650634.1"
                     /translation="MKIKVEDIPVQFHAMVEIIGIDKFIEVAKLYGGTNTYIPTYKGL
                     FRYARNRDIVKQFNGVNHNELAIRYNMCVSNIKRILNENSV"
     gene            10708..11946
                     /locus_tag="PC465_003358"
     CDS             10708..11946
                     /locus_tag="PC465_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HDF2650635.1"
                     /translation="MNKGFYKLNSVVLNFDIKNDVNKIRFNHYIMRKENIQRLQGTLP
                     NGQFYMTVRRAATDLQLSISTISRLVKEFLDLGIIRLVSKGVKGNRSVYSYVSIEFNG
                     SLFDDSKYMELDCVCNDEFIDNSGIEFDCDSKDNSFNGDINVETVHCINEYFSDDDVE
                     HNYNNFYNKDTMKDKAISNISTIKKYIDESFDTNKSENSNLQQESINFNFNDTCNEID
                     KRTNNSIENNQNKRPMRLSDISVLSDKGMTNKKNYFNHNHGIQKGTKSVTKKKESLNK
                     FNKKNIQQSIINMLNKKSGKNFKIDSPISIKLINERLKEGYVLEDFYKVIEVKVAKWK
                     NTIMEMYIRPETLFSYKFESYVNENISMKSQSNVHPCKEGNSNDSSNYIHSDYTTYDG
                     SVRERKKYENVRYWNPICEI"
BASE COUNT         4487 a         1444 c         1635 g         4558 t
ORIGIN      
        1 ataaaacacc aatgatttta ttactttaaa aatctaataa ccttttttat tataaaatac
       61 caataatttt tttgaatttc ttataagtta atagatatat aaggtacata taaaccccac
      121 aaatccctat aaaacctaag tttatcaaaa gagcattgac ctcactattg acgattctac
      181 catcattatt taacataatc ataaaattaa acagataaat taaaaaactt cctgcaataa
      241 gagggtatga aaatactttc tttaattgat ttctaataca gaactttata taatcattgt
      301 ttgctcctaa tcgatttaaa tccataaaga cctgcttgtg atttatagct atagtaacac
      361 cccttgtata tgcaatgatt cctactgctg taaaacatat gattgccaca tatatgaata
      421 acattaagaa gactgccatg ttttttatca tatcttggct ttgtaaaatt ttaaagttag
      481 gatagtattt ccaattaaga tacaactgat tgttgtttgg gtctagtttt aaatgacctt
      541 caccacttgg atattcttca tccataaaat attttcttcc agttgattca taacgttttt
      601 ttacgtattc atcataacca ctgaacatgc ccatttcctt agatgttctt tttataattt
      661 ctttctttaa gtcattggca aaagcatagg tatctttatc tacattaaat agtatagaat
      721 tattgtaatt ttttatggat aaatctttag taaatgattt ataatcctca tcattaagga
      781 cataggcgtt catacttcta ttttgaaaaa aagaaccatt aaatattatt tttccagcat
      841 atctaaaggg gatttctttt tctgtgactg ggcttgatat aaatttggta tatttataat
      901 cttgattttc atttccttta tttacaacag caagatattc accatttttt atagttattg
      961 gtttgccaat tagcttggaa aaatctttag aattaaagaa catatcatag gagctttttt
     1021 tcatatatac cttttcgata gttccatctt tatgatatat tgattctaca ccatcaacaa
     1081 ttaattctat agaaggaatt tccatatagt tttgaatttt tatattgtgt ttatctgcta
     1141 attgttcaat atcttttttt gatacctgtt tatctctttg attgtaggta aaagtataat
     1201 ctatagggtt atttttaaga gtatcataga tacctgtaac catattagga acatagaata
     1261 cagcaaataa tgctcctgca atcaaaaatg aaataacaca catgtttttt actgtttgtc
     1321 ttcccataaa tctcatcatg ctagttgata tgatgttttt atagtatttc tctggatgtt
     1381 ttcctctttt agcatgtaca actatgtatg tcataatcat atatattcca ataagagaga
     1441 gtagataagt aaagctccat acagatggta gtctataatt taatttgttt atagttagtg
     1501 aaggtacgag atatcctaga aaaataccta gtataataaa aattatacct aatataccat
     1561 accagtcctt tacatcctgt attggttcag atattctctg gtcatttaat atatcaatta
     1621 tatttgtacg attaataaat tttacagaaa gtataaatat gcataatgtc acaaatacac
     1681 taaatataaa tccatatatg aatccttgag ttccaaaatg atatgtcatt tctctggtat
     1741 caataatcac taattgaaat attttccata taccaaaaga tacaggaata cttaatataa
     1801 gacctaaaaa acagcatact actgaaatta acaatatctc tgaaaataga agttttttta
     1861 atttcttctt atctgttcct agagccatga aaataccaat ttccttgctt ttaaatttta
     1921 aaaagaggga agatgcgtat gtagtaaaga cagtgcatcc taatatagca actgagaata
     1981 tcattgtagc ctgttttctg ctatctccac cagttggaag tatgttttgt attgttgggc
     2041 taaaataaat tagagcatat gaagttacta ataccacaga aagtattata caaaagaata
     2101 aagttgtata gttcttccaa ttataggctc gaagtttact gtataattta ttaattgtca
     2161 tcttgagcgc ctcccatttc ttttaaaact tctagtaatt catctaggaa tttatgtctt
     2221 gaatttgatt ttacaacttc tttataaatt attccatctt taagcacaat aactcggtca
     2281 cagaagcttg ctgaaaagct atcgtgtgta accatgagta tagtagcatc taattcttgc
     2341 tttgctttta aaaatgattc aatgactgta cgacaagact tactatcaag gttaccagtt
     2401 ggttcatctg ctaatattaa atctgggttg ttcatgagtg ctcttgctac tgctgtacgc
     2461 tgtttttctc caccagatat ttcggcaggg tatttttttc tgatatgttc aataccaaat
     2521 agctcacata gattaattgc acggttttcc atttgtaaga cttgactacc tttgataatt
     2581 tgtggaacac atatattttc aaagacacta agaccatcaa atagcatgaa gtcttggaat
     2641 acaaatccta gttgttgatt tctaacttct gaaagttcct tttcttttaa atttcttata
     2701 ttattatttc caagaattat ttccccatta tcaattggga taaaacatga aatacaattt
     2761 aaaagagtag tttttccact tcctgatgaa cccatgattg cgacaaattc tcctttgttg
     2821 atttcaaaag aaatattttt taatacagga tatgttttac tgcctgtttt atatgattta
     2881 cataattggt ttactttaag catatatatc atcctcactt tcatttatct tgtaagtcaa
     2941 tgatagcatt tgaaagggga ggagggatat gagctatatt gtaatagttg gatgtttttt
     3001 tgtaatgttt gaaaatatat tgtttggata gtgtgagagg ttattattat agttaaattg
     3061 attatattat tggaggattt agagggttat ttttaggtat taattgttgt gctaaagtaa
     3121 tatgatgtgg aacattgaag gtgtagttag aaaagaagta tatagtaaaa gtaaaaaggt
     3181 tatagaataa cgaatgttgt attgaaaaaa atgatgtaaa taatgtatag tagggttaaa
     3241 aagaaaaaaa gaattataga gcagtaagat tatttaatgg aatgtattgt aaataatttg
     3301 aaaggattta ggggctatta acacaatgta attgagaaaa tatattggag ttttggaaat
     3361 aaataggttg ttaaaaacaa ttgaaattta taataaaaag gttaaaaagt attattagta
     3421 taggtatgat agataatttt agaaagtgga agtattttag actatgctga aaagtgattg
     3481 atatgatttt gagatattaa aatattacta tattatagta aagaagttaa aataataaaa
     3541 tgttgtaata ataaaggttt gtagtataat aaagaactgt aataaataag actttgcaat
     3601 gtaatagaaa tgctgtaata ataaaggtct gtagtatagc aaagaactgt aataaataag
     3661 agattgtaat aataaaagtc tgtagtataa taaagaactg taataaataa gactttacaa
     3721 tgtaatagaa atgctgtaat aataaaggtc tgtagtataa taaagaactg taataaataa
     3781 gactttacaa tataatagaa atgttgcaat aacaaaatac cataataaat aagagtttgc
     3841 aatataatag aaatactgta ataacaaaac actgcaataa ataagagatt gtaatataac
     3901 aaaatcctat aataaataag attttacaat ataataaaaa tcctataata aataggactc
     3961 tgtaatataa taaaatgctg taacaacaaa acactataat aaataagacc ctgtaatata
     4021 ataaaaatac tataatatag taaaaatcat gcaataataa aaatctataa taataaacct
     4081 cagcataaca aagacattaa tttcttacta aaaaggccac cacaattaac agtgaaaaag
     4141 caattgaaag tattgaaaaa gtaaagtgag aattagagtc attattacga ttattaagtt
     4201 ttatccataa accacatata attgtacaca acaataaaat tgctgatatt actcctataa
     4261 atgtaaaaaa cattaaaatt cctccccctt atttaatgca agtattttta gtcaatgaga
     4321 atattttcaa acgttaccat aaaataaaaa aatgtacata aaaaattaat atagtattat
     4381 tttgtaatat ctaccaataa taaatctaat tgaaaatcta ttaaaccatt tctctgttca
     4441 acattaagaa tatcaatacc actatacttg aaaaaagcat tagaacgaag aaaaagcaac
     4501 tgaataaatg aagttatttg atacgcaata gttctgtatt cagcttcagt ttttttgtta
     4561 ttctgatttt catagtgagc cttaattaaa ggtagtatct caaatggata aacaatttct
     4621 tcctgtatca atatataggg tacagaaatc tttataaatt gactatgttc acctataaaa
     4681 tcaaaaaatg caattagtat ttcccttaat tgctgtttag gtgctaaatt tttagtatca
     4741 tgtgtagcct tatattcatc catatgacgc tttaaaaatt ttttaataga aatattaatt
     4801 aactcctctt tagatttaaa ataataatta atcatagcta aattgacatt tgctttagct
     4861 acaatttctc tagccgtaat gcttgaaaca tctctatgtg aagatagtaa ctggattgtg
     4921 gcattaatta attgttcctt tgttgaatct gctttcataa tttttcccct taaaagtttc
     4981 ttcataaaaa aattaaacat gtttaataca cgtttagata ctatcatgaa aattttggga
     5041 tgtcaatggg tgattagtac ttaagtattt aagtactaat cgattagact tttataaggg
     5101 ggatttgaat ttctgtaaga taattttcag gatttatttc attatgttca cctttatgac
     5161 cgatttgtct atttatacct gatatttgat aatcactatt tttatctaac caataacaga
     5221 acgattcata tgcaccagct atattttcat atggaccata aaccatagta catgccatca
     5281 tatcaatttc ttctgtctca cgatatataa atccagattt gttctttcca atcttcttta
     5341 caaccattcc aacttcaata tctacaccat tatctttgac ttcttcatca tggtaaaaag
     5401 ctatgttatt gttggattga cgtgatactt ctatatgttc ttctttgata aatttagata
     5461 gcttttccca gagtatacct tcagattggt agtctggaat tatctctcta agtgatatga
     5521 ttttataact tggaatcttt ttaaagacaa cattgtaatg aatttcatct ttatcacagt
     5581 ttatagcttc tataaattta tcaattttat ttattctttg ttgttcctgc tttatttcct
     5641 tttgtatttc attctttttt ctattcaatt ccttaattac aaattcatca ttccaattat
     5701 gtacgatatt tgctatttct gcaacgctaa attttgaatc tctcaataat acaattcttt
     5761 gtaatattga aatctgttca actgagtata atctatgacc tgtatatttg tctgtttttg
     5821 caggttttaa aataccaagt tcatcataat aacgcaacat acgaatagaa atttgtgtta
     5881 gttttgaaac ctctcctatt ttaaacatga aaatatgacc tccttttcac ttataatcag
     5941 tatatatttt gtttttatat acttcaagcg tttgtggaaa tacaattatt ttccagatgt
     6001 tacaataaat tatagagagt aaattatatt taagtagtaa tcgtatcaaa tcatagatta
     6061 tcttaattta taattcatat taaaattacc agtctaactc aaattcaaaa tcatccgact
     6121 ttatctgttc aatttcagaa tttaccttct gtttaaattt attagaagaa atcatatata
     6181 caagaaatat taaaccaaat attatttgta catattgagc tattacacat aatttaatag
     6241 ggtagtgtag aagtaattga atgttgaaaa aatagtacat catatgaact aacccagctg
     6301 ataaaatgct tctacttgta ttgatatata caaaattaat tataaagttt aaaagtacaa
     6361 tgtttggtat aaataaaaaa gcatcaaata gggagtattg tgccaaatta tatggtattt
     6421 gattaggtgt aaaatacgac cctagatacc agattccaca aacaagccct aaaataattg
     6481 aagagcctat aaatccaaat ctaactaata atttgtcaat ggcatatcct ctccatccag
     6541 cttcttgact aagtatactc aatataaaac ttgctaatag catataagct attttagaag
     6601 gtctaaacac tgctatgtgt atccaatcta tatcagaagt ttttacatta aagtaatttc
     6661 cgattattaa cgaagtaata aaagttaaag caaaaaataa tattgttaat agtatccatt
     6721 ttattctaat ttctttaaag cttaggtatc tataaataaa atcttgtttt gcactttgtg
     6781 gatagattgt agaaataaaa aatagaccta caatagctgg tgatgtatat gcaagataaa
     6841 aaatgatttc tccaagtatt gtatttgtaa ttccgagcaa cgcaggtgta agactgaata
     6901 tccagttcaa tactagcgta aatgtaaaga aatagattaa gtgtttgttt gtattaaagg
     6961 gggtgttata tagttgcatt ttttcactat ccttccgttt tataatgaag ttttaatttt
     7021 tattaattgt ttatttattt ttatatgtat taagttatcg cttgatgtta gttattgcct
     7081 ataataatat cctatttttt atattttgat taattatttt tacactaaat ataattaatt
     7141 agtatttaat attgaatata ttatattatt attaattatt aaataggtca ataaatttgc
     7201 aattagtgat attaataaat tactttagat ttttattaaa tgtttagctt ttctttaata
     7261 ttttttatat aacgacgatt tataataact ttttcgttgt tttttaaagt agcttgcatg
     7321 cgattatgtg atattacttt tatacttttt atgtagtcca tatttaaaat catggattta
     7381 gatattcgtg agaaggatgt attagctaat aattttgata atttatatat ttttaaatca
     7441 atttcaaata catcatcttc ataataagca aatgttttat ttccaactgt ctcaaagtat
     7501 aaaatatcat agacattgag tttataaatc tctcctgatt ttttaccttt tatatcaagt
     7561 aacggtgtac tcaataatga aattattttt tcaatgttat tatctagagc agaacatttt
     7621 atggttattt caatatcatc acaattaata ccttgttcga catgtatttt cattaatcat
     7681 cacctcattt tattactgtc attagaatag cattatatct tattgagtcc aactagatgc
     7741 gttctaaatt tcaaattaag catagtgaaa ttcaaaaata aaacagtgaa attcaaattt
     7801 gaggtggtaa aattcaaaaa aatactatgg atatttggat aaattatcca aatatcctag
     7861 cattttacat agaatatgcc taattatttt acaaatagac ctattttatg acttacatat
     7921 attgtcaaat tacttcttaa atatcaaaat atttttggat aatgtatcaa tactgtttga
     7981 taaagtattt aatttaccct caattctaac caataagtac atggatagag ctataggaaa
     8041 accaacattg gttattaaca gttgtaaact atcatccata aaattagccc cctattctat
     8101 aactaagtca taaggagtgg tatttgtttc cacaaccttg gcttcaacca cagaagctag
     8161 gtcaaatcct ccaaccgaaa aaatattttt agatactatc aaatccatga cagattttat
     8221 attttcttca gttaaatcat cctttggatt ttctatagaa aaagaaactt gtttatcctt
     8281 tacattttta aagctcatga ctaatttttt cttaatttcc atataattac ctccgatata
     8341 ataatttata ttttaattgt ttgcttgtta atattggtat tttaattgtc aatattagtg
     8401 ttttgcttgt tagtattaat atttcaattg tcaatattaa tgttttgctt gttagtatta
     8461 atatttcaat tgtcaatatt agtgttttgt ttgttagtat cagtgtttca attgtcaata
     8521 ttagtgtttt gcttgttagt attgatattt caattgtcaa tattagtgtt ttgcttgtta
     8581 gtattgatat ttcaattgtc aatattaatg ttttgcttgt tagtattaat atttcaattg
     8641 tcaatattag tgttttgctt gttagtatta gtatttcaat tgtcaatatt agtgttttgc
     8701 ttgttagtat tagtatttca attgtcaata ttaatgtttt gcttgttagt attagtattt
     8761 caattgtcaa tattaatgtt ttgcttgtta gtattagtat ttcaattgtc aatattagtg
     8821 ttttgcttgt tagtattagt atttcaattg tcaatattag tgttttgctt gttagtatca
     8881 gtgtttcaat tgtcaatatt agtattttaa ttgttgactc tagttattgc tgatatagaa
     8941 aatatttaat ttatttcaat taattagatt aaagtagggt agcatctaaa atagctaaca
     9001 tgtttaagtt gaaatacgtt taatatatta atttttcaaa gcgttaatat attaaagtta
     9061 taaccaaaat tgaagttata atctgccaaa tctatagcgt attaagtacg ttatataact
     9121 taatctttta tataaagagt taatttttta atttgtaaag cagagtacgt ttaaaagata
     9181 ctatttagat agtgatgtac tatctaattt taaaatatct acaatagggt tctcttgaag
     9241 acttgctatt gcttctgcaa cagcataaac atcttcattt aatgcctctg cttttacatt
     9301 tgcaaatgat ttacttttaa caactgcctt acccttatca tcaaaaccag catccaattt
     9361 tagttttata ctagataaat tttttgttga aacaacttcc ataaaattac ctcctaaaaa
     9421 tttaatttca aagatttgtc gactttcttt gttagctata atactatcat ctaagataat
     9481 atcggagtta aacagtaatt tctaaagatt ttttgtgtaa atttttatag gaaaaatttt
     9541 acttttttgc tgatgaaaaa gtttacaagt tatttgtgaa gatatgttct tagtgttttg
     9601 aaatagtatt tgtatatatt cctgcttagt tgagatagtt ttgtatggat tttcatatgt
     9661 gtagagttaa atgttaggta ctaaagttta tgttaaatta aatgttaaag cttatgttaa
     9721 aaattttatt aaatttaatc tgtaaataaa aaagttaaaa gtccaatatt aacattttac
     9781 ttttaaacca ttaaaatctt tattaaagct aacaaagtta taagttatga gaaattttat
     9841 tgaagttaat acaaaaatta attttaaagc taagaaatta tttattagat tcaataaaac
     9901 taataaatat agtttagtca ataatgtatt aaataaaaac tttgttaagt ctataaaaat
     9961 atcttaaagg aggtgtaact tatgaagata aaagtggagg atataccagt tcaatttcat
    10021 gcaatggtag aaataattgg aattgataag tttatagagg ttgccaagtt gtatggagga
    10081 acaaatactt atatacctac gtataagggg ctttttagat atgctagaaa tagggatata
    10141 gtaaaacaat ttaatggagt caaccacaat gaattggcta ttagatataa tatgtgtgta
    10201 agcaatatta agcgaatact caatgaaaat agtgtttaaa tataataaaa taatgtttaa
    10261 acataatgaa aatagccttg ttaaacgtaa gagtaaagac aaagaagatg ttttataaag
    10321 tttttttaga caaattaact aaatttacta cttattaatt taaatacatt gtatattcta
    10381 taaaaaaatt tgttaaatac tggagatata ttgagaatac aaagaaaatg gtcgaaaata
    10441 tttgttggct aaaaaataga taaaatgata caattgcttg tataaagggg aaaaataaac
    10501 aaataaacta tataaataaa gaaatagcaa ttaatatgac ataatatatt tataaaatta
    10561 agaatataaa tagatatttt aaggtattag ttgttaaatt aggaaatatt aaaaaaaata
    10621 tatatttata tttaaactat tttgttattt atataaaaat acttatctag ttactagcaa
    10681 ttattagtag aaatggggga aatagagatg aataagggat tttacaaatt aaattcagtg
    10741 gtattgaact ttgatattaa gaatgatgtt aacaagataa gatttaatca ttatataatg
    10801 agaaaagaaa acatacaaag acttcaagga actctgccaa acggacaatt ttatatgaca
    10861 gtgagaagag ctgctacaga tttacaactt tctatttcta ctataagtag gcttgtaaaa
    10921 gagtttttgg atttagggat aataagatta gtgtctaagg gtgtaaaagg taatcgttct
    10981 gtatatagtt acgtaagtat agagtttaat ggaagtttat ttgatgatag taaatatatg
    11041 gaacttgact gtgtatgtaa tgatgaattt attgataata gtggcataga gtttgattgt
    11101 gatagcaaag ataattcttt taatggagat ataaatgtag aaactgtgca ttgcattaat
    11161 gagtatttct ctgatgatga tgtagagcat aattataaca atttctataa caaagatact
    11221 atgaaggata aagccatttc taatattagc actatcaaaa aatatattga tgaatctttt
    11281 gatacaaata aatcagaaaa ttctaactta caacaggagt caataaattt caactttaat
    11341 gatacatgca atgaaataga taaaagaacg aataatagta tagaaaataa tcaaaataaa
    11401 aggcctatga gattgagtga catcagtgtt ttaagtgata aaggtatgac aaataaaaag
    11461 aattacttta atcataatca tggtatacaa aaagggacta aatctgtaac aaagaaaaaa
    11521 gaatccttaa ataaatttaa taaaaaaaat atacagcaaa gcattataaa tatgctaaat
    11581 aaaaaatcag gtaagaattt taaaatcgat tctccaataa gcataaaact tatcaatgaa
    11641 aggctaaagg aaggctatgt cttagaagat ttctacaaag ttattgaggt aaaagtggct
    11701 aagtggaaaa ataccataat ggaaatgtat ataagaccag aaaccttgtt tagctataag
    11761 tttgaatcct atgtaaatga aaacatatct atgaaaagtc aaagtaatgt tcacccatgt
    11821 aaagaaggca atagtaatga tagcagtaat tatatacatt ctgattatac aacatatgat
    11881 ggcagtgtgc gtgagagaaa aaaatatgag aatgtaagat actggaatcc tatatgtgaa
    11941 atttaattag tttaagaatg tatttatgat aaataagata ttaatagaga atagtgagct
    12001 atagcaaatg atatatcaat agttggtagt aagttatatt aagcaagata ttactatcag
    12061 gtagtgaatt gtattgaacg atatatcaat aattggtagt aaattatatt aagtaagata
    12121 ttac
//
LOCUS       DAMJXI010000095        11875 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.100, whole genome shotgun sequence.
ACCESSION   DAMJXI010000095 DAMJXI010000000
VERSION     DAMJXI010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11875
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.100"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            106..669
                     /locus_tag="PC465_003359"
     CDS             106..669
                     /locus_tag="PC465_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650636.1"
                     /translation="MNKVYIVTTYTGTILSYLIRNISKKLYTHVSISLNENLKPMYSF
                     GRLNPRNPFIGGFVEENINQGLYAIRKNTVCRVYSLEVDNLQYENLYKNIKLISDYRE
                     DYYYDTMALIYLLMNIQRQSEYKYVCSNFVADMLEKSEIDILNKQAFEVTPNDFYNLS
                     GLTLEYEGLLSEYNSRQHSYVSKIANI"
     gene            1066..2766
                     /locus_tag="PC465_003360"
     CDS             1066..2766
                     /locus_tag="PC465_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650637.1"
                     /translation="MKRYLKTYGVALIIVIIYAFIKLPVLRLDFTSLFSVGIIFFVVA
                     GILDMMLDRNERASKMAKYNFSIAIALLVYIVVVPFITSTPVLHAKSYRELLGKVTES
                     KFTDDISPVSVNDIRLVDEDMAMKLGDKKLGEVPAIGSVSKLGKFHIQNVDGELYWVA
                     PLVHRDIIKWITSLSGTSGYVKVSASNPQDVQLVQEIDGKPIKIVYQPEAYLHQDLQR
                     HLYIHGIVNVGMTDFTLEINDEGRPYWVVSLYEHKIGYGGANATGIATVDAETGKINV
                     YDVKNTPKWVDRIQPQSFVTDQIKDWGVYVNGFLNSVISEKGVLVPTEGTSLVYGNDN
                     RSYWYTGITSSGGDESTIGFMLVDSRTKEARLYKQPGATETAAMKSAEGNVQEKNYEA
                     TFPVMYNILGQPTYVSSLKDKAGLVKRVAFVSVEDYNVLGIGEDKNEALRNYKDALES
                     KGNDLKLDNDLKDEVLEGTVTRISPDVRGGNTNYYVTLDSNKDIIFRATSKVSSELPL
                     TQVGDKVKISYSKEESGVIEMSEFDNLNIANFEDKKAKEKTGTDENTDSKDSENQGNV
                     "
     gene            2936..3553
                     /locus_tag="PC465_003361"
     CDS             2936..3553
                     /locus_tag="PC465_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650638.1"
                     /translation="MTNMEKEILLLISRVRCVTESQFRKIYGDQKRYNKKNFKKTLRK
                     MCSEYTLKKYPCDVDYYNYKDLSYVYYLNGSKLFKGDDLIKALVGSELVVRINTAGCD
                     VKRFYRNVSVDDVKYDLFIEYTDQFGNIKQVLVDVDLNNEIDISKYENLSKKIDKSTI
                     PFFKVPNVLVVTPDNLSELNDLERYDNEYSINFIDLGLNKLFNCI"
     gene            3914..5107
                     /locus_tag="PC465_003362"
     CDS             3914..5107
                     /locus_tag="PC465_003362"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HDF2650639.1"
                     /translation="MSIIVQKYGGSSVADTEKIKSIAENIIERRKENPQMVIVVSAMG
                     KSTDEYITLAKELSNEPSKRELDALMSTGEMISASLLSIALNALGCKAISYNAYQLNI
                     KTSGLHGKSQIDDINVNRIKNSLDEGNVVIVTGFQGINEDGDVTTLGRGGSDTSAVAL
                     AVKLNGKCEIYTDVDGIYFTDPRKYSKASKLDEIEYEEMLELASLGAQVMHSRSIELA
                     QKYGVEIYVGRTCGTEKGTYIRGGKDMKLEDKVITGLATSDDDSSITIKDFKAENISS
                     LFEDIATIGISVDMISQTAPILDKISVSFTVPKEELGECKKIVSKYTDEEHVVIDNNI
                     TKFSLVGLGMKNTSGVAAKVFKIFNENGIMIKLITTSEIRITCAINSDDKQVAIEKIA
                     EVFNI"
     gene            5125..6417
                     /gene="lysA"
                     /locus_tag="PC465_003363"
     CDS             5125..6417
                     /gene="lysA"
                     /locus_tag="PC465_003363"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HDF2650640.1"
                     /translation="MKLHGTMTVNNDELYIGGVSCLELSKKYQTPLYVFDEALVRQNC
                     REYIEYFKAREGKNKVAYAGKAFLPLYMCNLINEEQMCLDVVSGGELYTAYKSNFPME
                     KVFFHGNNKTKEEINMGLDLGVGKFVVDNFYELDLLEALCEDKGKTQEIYFRITPGIE
                     AHTHDYIKTGQIDSKFGFALVNGDLFRAIEKLSEYKNIKLVGLHAHIGSQIFDVEPYI
                     DTVDIMMNLVKEIKEKFNIQLTEIDLGGGVGVYYSEGDKPKTIKEFCETIITKAETSC
                     KELGIEVPTLVIEPGRSIVANAGSTLYTVGSIKDIKDVRVYVSVDGGMTDNVRPSLYQ
                     ASYECSIVNKINHEAMNHVTIAGKCCESGDILIGDINIMDIKSGDILITTSTGAYGYS
                     MSSNYNKIPRAAVVSVFDGNDKIICKRQSYEDLLALEI"
     gene            6634..7293
                     /locus_tag="PC465_003364"
     CDS             6634..7293
                     /locus_tag="PC465_003364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2650641.1"
                     /translation="MRGRVILLISILSIFLVGCSFNKKDEINLVEQGKTYLEKHNYKK
                     AMESLSSALEEDSTNENARAMYMQAMRMSNMTEFEELKNYEGAIKELKLIEKIKNGSS
                     VIKEEATKKKEELTKLEKEQNEAEEQRKKKAKDTAGEDRYRVESDARKSSYSGSSKNN
                     KSSSKNNDKKSDSNKSDNNNSSSQNQEKPNNSNPTPAPTPQDTTGGSDSGGNSQNSNN
                     Q"
     gene            complement(7448..8533)
                     /locus_tag="PC465_003365"
     CDS             complement(7448..8533)
                     /locus_tag="PC465_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF2650642.1"
                     /translation="MIIISKENIKYYLIVVFIGILFFKFINTPSDFISSIEGFLKFFS
                     PFLLAILLALLLNPLVMLFEVKFKAHRLLAIFLSYIFIGFILAFAIRLLIPSIANTLN
                     RLINEMPMYTDYIDSFIEKNMSNIDFLKTLIPHIQHSLDNLLKEASNFVGKIPKNFLI
                     YTLSISSMLFNMTMGFILSIYIIYDKEKIALGFKRFLYSSTARNKADNIIEFFRTTHD
                     IFYDYLLGRILDSLIIGIIAFLGFQFVIRIENALFLASIIFLGNIIPYFGPFIGAIPP
                     IAMTILYSPQKTIWVIAFLFILQQLDGNFIEPKVMGNQVGIGAIWVISAILVGQSLFG
                     FIGVFLSVPIAAVVKTYVDKYIDNRLQ"
     gene            8724..9440
                     /locus_tag="PC465_003366"
     CDS             8724..9440
                     /locus_tag="PC465_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDF2650643.1"
                     /translation="MRINKYIASCGIASRRKAEEIILGGRIKVNGSVVKELSFNIDEE
                     KDIVEFDNKKVKPSENYIYIVLNKPEGYITTVKDQFNRPSVIDILKDVRERVYPIGRL
                     DYETSGLLILTNDGDLTYKLTHPKHEIDKTYVASVKGIISDDEIRQFETGLKIEDYTT
                     APAKIRVTKENKEKNYSVCEITIHEGRNRQVRKMCKAINHPVLNLRRISVGKIVLKDT
                     KVGEYRYLTEDEIKYLKSIK"
     gene            9498..10076
                     /locus_tag="PC465_003367"
     CDS             9498..10076
                     /locus_tag="PC465_003367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF2650644.1"
                     /translation="MAYAKYLTKITDINKFYLENIINEGDIVIDATMGNGYDTRYLAE
                     KVGEKGFVYAFDIQEEAIKSTRKKLEKEGYTDRVKLIFDGHEKMNQYIKEEVSCVLFN
                     LGYLPRAKHSIITKPDTTLKAIKLSLEMLKENGVISIAIYTGHDGGQEEKDCIYNLVN
                     NLNQDEFNVLESKFLNQVNNPPQLILIEKKKA"
     gene            10470..11342
                     /locus_tag="PC465_003368"
     CDS             10470..11342
                     /locus_tag="PC465_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2650645.1"
                     /translation="MEETNEMKDSKHLISNIQSQYTRLSKGQKLIAQYILNNYDKVAF
                     MTACKLGETVGVSESTVVRFANALGYSGYPKLQAALQELIKNKLTTVQRVEMAHDYSD
                     DFAILNKVLKSDIDNIRSTLEEIDERAFKEASNKLLRARKIYILGMRSSFVVAQYLGF
                     YLDIILDNVHIIRMDMGDAFEQIVRINEEDVIVAISFPRYSKKSYQIVNYAKEKGAHV
                     ISLTDSLFAPVASLADNTLLVKSNMASFVDSLVPALSISNALAISVGMKEKEDIKQHF
                     DDLEQIWKRYSVYE"
BASE COUNT         4892 a         1226 c         2021 g         3736 t
ORIGIN      
        1 ccttaaaatc aaaatttgta aaaccacatt tattatgtta gaatatctta tgatattaaa
       61 ttgtaagtgt ataatattat ttagttacta gattgggggg aaatgatgaa taaagtctat
      121 attgtaacaa catatacagg aactatatta tcttacttaa taaggaatat aagtaaaaag
      181 ctgtatacac atgtgtcaat atcattaaat gaaaatctaa aaccaatgta ttcttttgga
      241 aggctaaatc caaggaatcc atttattgga ggatttgttg aagaaaatat aaatcaagga
      301 ttatatgcta taagaaaaaa cactgtgtgt agggtatatt cgttagaagt agataattta
      361 caatatgaaa atctatataa aaatataaaa ttaattagtg attatagaga agattactat
      421 tacgatacaa tggcattaat atatttacta atgaatattc agagacaatc tgaatataaa
      481 tatgtatgtt caaattttgt tgctgacatg ttagaaaaaa gtgagataga cattttaaat
      541 aaacaagcat ttgaagtaac gccaaatgat ttttataatt tatctggctt aaccttagag
      601 tatgaaggtt tattatcaga atataattct agacaacatt cttatgtatc aaaaatcgca
      661 aacatttaaa aacttgattt ggagtttttc atataaaaaa atattgctag ataattaggc
      721 tgaagatagt agtttaactt cgataggatt aagaatttgt aaatcttagt tagaatactt
      781 tcttcagttt ttaaatttct gctaatattt gtatttttat aatatttttg gatatatata
      841 atacagaata gtgcaaaaat cccactcctt taggtgcggg atggatagca caaacagtat
      901 ataaaaagta tttatacata cacgtataat gttaaatata gttgaataag cagaactata
      961 aatatataaa gatatcttaa tatataataa atatgataaa tatttatttt ttgtaaatat
     1021 atggatataa tagtaataat aacatttttt agagaggagt attaaatgaa acgatatctt
     1081 aaaacatatg gagttgcatt aataatagta ataatttatg catttattaa attacctgta
     1141 ctaagattag attttacatc tttattttca gtaggaataa ttttctttgt tgtagcagga
     1201 atactagata tgatgttaga tagaaatgaa agagcatcta aaatggctaa atataatttt
     1261 tcaatagcaa tagctttgct tgtgtatatt gtagtagttc cctttataac ttctacacct
     1321 gtacttcatg caaaatcata tagagaacta ttgggaaaag taactgaaag taaatttact
     1381 gatgacatta gccctgtcag tgtaaatgac attcgtcttg tagatgaaga tatggcaatg
     1441 aaattaggtg acaaaaagct tggagaagtt cctgcaatag ggagtgtatc caaattagga
     1501 aaatttcata tacaaaatgt agatggagag ttgtactggg tagcgcctct tgttcacaga
     1561 gacataatta aatggataac atctctaagt ggtacaagtg gttatgtaaa agtatcagct
     1621 agtaatcctc aagacgtcca attagttcaa gaaatagatg gaaagccaat aaagatagtt
     1681 taccaaccag aagcctactt acatcaggat ttacaaagac atttatacat acatggtatt
     1741 gtaaatgttg gtatgacaga tttcactctt gaaataaatg atgaaggaag accttattgg
     1801 gttgtaagtt tatatgaaca taaaattggc tatggaggag caaatgcaac aggaatagcc
     1861 actgttgatg cagaaactgg aaaaataaat gtttatgatg ttaaaaacac acctaaatgg
     1921 gtggatagaa tacaaccaca aagctttgta acagaccaga ttaaagactg gggtgtttat
     1981 gttaatggat ttttaaactc tgttatatca gaaaagggag ttttagtacc aacagaaggt
     2041 acatcattag tttatggcaa tgataacagg tcttattggt atacaggtat aacatcttca
     2101 ggtggagatg aatctacaat tggatttatg ttagttgatt ctagaacaaa agaagctaga
     2161 ttatataaac aaccaggagc tactgaaacg gctgcaatga aatcagctga aggtaatgtt
     2221 caagaaaaaa attatgaagc gacgttccct gtaatgtata atatattggg tcagccaaca
     2281 tatgtatcat cattaaaaga taaggctggt cttgttaaga gagttgcatt tgtatctgtt
     2341 gaagattata atgtacttgg aataggtgaa gataagaatg aagcattaag aaactataag
     2401 gatgcattag aatctaaggg taatgattta aaacttgata atgatttaaa agatgaggta
     2461 ttagaaggca cagtgacaag aataagccca gatgtgcgag gtggtaacac taattattat
     2521 gtaactttag attcaaataa agatataata tttagggcta cttcaaaagt atctagcgaa
     2581 ttgccattga ctcaggttgg tgataaagtc aaaatatcgt attcaaaaga agaatctggt
     2641 gtaatagaaa tgtcagaatt tgataaccta aatattgcaa actttgaaga taaaaaagca
     2701 aaagaaaaaa caggaactga tgaaaataca gattccaaag attctgaaaa tcaaggtaat
     2761 gtataattta aataaaaaga ttgataatag tatttaacat agtgatagct aatttttata
     2821 gaatttaatt ctataaaaat tagctatttt attttaattc tttgtaaatt taatgtcata
     2881 aaattaatat aatattagta caactttgca aataatactt caaggagaat gtactatgac
     2941 gaatatggaa aaagagatat tacttttaat tagcagggtt agatgtgtta cagagtctca
     3001 atttagaaaa atttatggag accaaaaaag atacaataaa aaaaatttta aaaaaacttt
     3061 gagaaaaatg tgtagtgaat atacactaaa aaaatatcct tgtgatgtgg attattataa
     3121 ttataaagac ctctcttatg tatactattt aaacggtagt aaacttttta agggagatga
     3181 tttaataaag gctctagtag gatcagaatt agttgttaga atcaatactg caggttgtga
     3241 tgtaaaaaga ttttaccgaa atgttagtgt agatgatgtg aaatacgatt tatttattga
     3301 atatacagac caatttggta atataaagca agttttagtt gatgttgact taaataatga
     3361 aatagacatt tctaaatacg aaaatctttc taaaaaaata gataaatcta caattccatt
     3421 ttttaaagta ccaaacgttt tggtagttac accagataat ctatccgaat taaatgattt
     3481 agagagatat gataatgagt atagcataaa ttttatagat ttaggattaa ataaactatt
     3541 taattgtata taagctaact ttagaaaaga aaactatcga tttgccacat tttgtaaaat
     3601 aattgttgca atattatata gaatatgata aaactatatt aataaattaa ttaaaaataa
     3661 tgagcctagg gtagaggtag ctgtattcaa tagtattcaa taggagctgg taagcgttga
     3721 taattgatga aagggtatat agccgaagaa attttgttga cggacaaatt ttctggactt
     3781 atgcagaata tgcataaggc tgtcactttt aaagtggtga gctacaaggt tacttggtct
     3841 atgaaattta cacgtccaaa gtataccttt gggcgttttt atttatcaaa atttagcttg
     3901 agggggagaa agcatgagta taattgttca aaaatatggt ggaagttcag tagcagatac
     3961 tgaaaaaata aaatcaatag cagaaaatat aatagaacga agaaaagaaa atccacaaat
     4021 ggtaatagtt gtgtctgcca tgggaaaatc cactgatgaa tatataactt tagcaaagga
     4081 attgagtaat gaacctagta agagggaatt agatgcttta atgtctactg gtgaaatgat
     4141 ttcagcatct ttattatcaa tagcattaaa tgcacttgga tgtaaagcta taagttataa
     4201 tgcttatcag ttaaatataa aaacgagtgg tcttcatgga aagtctcaaa ttgatgatat
     4261 aaacgtaaac agaattaaaa atagtttaga tgaaggaaat gtcgtgatag taactggatt
     4321 tcagggaatc aacgaagatg gtgatgtaac cactcttgga agaggtggtt cagatacatc
     4381 tgctgtagct cttgcggtta aattaaatgg aaaatgtgag atatatacag atgttgatgg
     4441 aatttatttt acagacccaa gaaaatattc aaaggctagt aaacttgatg agattgaata
     4501 tgaagaaatg cttgagttag cgagtttagg agcacaagta atgcattcaa gaagtataga
     4561 gcttgcacaa aaatatggtg ttgaaatcta tgtcggacgt acatgtggta cagaaaaagg
     4621 aacatatata agagggggaa aagacatgaa attagaggat aaagtaataa caggattagc
     4681 tactagtgat gatgacagtt ctataacaat aaaagatttt aaagctgaaa atatatctag
     4741 cttatttgaa gatatagcaa ctataggtat aagtgtagat atgataagcc aaactgcacc
     4801 tattttagat aagataagtg tatcatttac agttccaaaa gaagagttgg gagaatgtaa
     4861 aaagatagta tctaaatata cagatgaaga acatgtagtg attgataata atatcactaa
     4921 attttcttta gtaggtcttg gtatgaaaaa tacttctgga gttgctgcta aagtatttaa
     4981 gatattcaat gaaaatggta taatgataaa acttataact acatcagaga ttcgtataac
     5041 ttgtgctata aattctgatg ataagcaagt agctatagaa aaaatagcag aagtatttaa
     5101 tatataaaat ttggggaggc tattatgaaa cttcatggaa ctatgactgt aaataatgat
     5161 gaattatata ttggaggagt gagttgttta gaacttagta aaaaatatca aactccactt
     5221 tatgtatttg atgaagcttt agttagacaa aattgtagag aatatataga atattttaag
     5281 gctagagagg gaaaaaataa ggttgcttat gcagggaaag cttttttacc tctttacatg
     5341 tgtaatctta taaatgaaga acaaatgtgt ttagatgtag tttcaggagg cgagttatat
     5401 acagcttata aatcaaattt tcctatggaa aaagttttct ttcatggaaa caataagact
     5461 aaagaagaaa taaacatggg attagattta ggtgtaggta aatttgtggt ggataatttt
     5521 tatgaattag atttgcttga agcattatgt gaagataaag gtaaaactca agagatatac
     5581 tttagaataa ctcctggtat agaagctcat acacatgatt atataaaaac tggacagata
     5641 gattctaaat ttggatttgc tttagtaaat ggagatttat ttagagcaat agaaaaatta
     5701 agtgaatata aaaatattaa acttgtgggt cttcacgctc atataggttc acaaatattt
     5761 gatgtagaac catacataga tacagtggat ataatgatga acttggtaaa agaaataaaa
     5821 gaaaaattca acatacaact aacagaaatt gacctaggtg gaggagttgg cgtttattat
     5881 agcgaaggag ataaacctaa aactataaaa gagttttgtg aaactataat cactaaagca
     5941 gaaacttcat gtaaagagct tggaatagaa gtacctacat tggtaataga accaggaaga
     6001 tcaatagttg caaatgcagg aagtacattg tatacagtag gttctataaa agatataaaa
     6061 gatgttaggg tttatgtaag tgtagatgga ggtatgacag ataatgtaag accttcgttg
     6121 taccaagcta gttatgagtg tagtattgtg aataaaatta atcatgaggc tatgaatcat
     6181 gtaacaatag ctggaaaatg ttgtgagagt ggagatatat taattggaga tataaacata
     6241 atggatatta aaagtggaga tatacttata acaacatcaa ctggtgcata tggatattca
     6301 atgtcttcaa attataataa aataccaaga gcagcagtag tatcagtatt tgatggaaat
     6361 gataagataa tttgtaagag acaaagctat gaggacttat tagctttaga gatataaaat
     6421 ggagaagtat ataataaaaa ttaaatatta aagtttatta tgagcagatt tgctaggata
     6481 tgtatctcta aattaatttt tggtttattg tatcgttcgt agcatatctg cttatttttt
     6541 gttttactaa caaatttctt gtaataaata taaaatattt taaaaacttt ataattatga
     6601 taaaatttaa agtatatgac aaggagggat ttaatgagag gaagagtaat tttattaata
     6661 tcgatattat ctatatttct tgtaggatgt tcatttaata aaaaagatga aataaattta
     6721 gtagagcaag gaaaaacata tttagaaaaa cataactata aaaaagctat ggaatcatta
     6781 tcctctgcac tggaagaaga tagtactaat gagaatgcaa gagctatgta tatgcaagct
     6841 atgagaatgt caaatatgac ggagtttgaa gaattaaaaa attatgaggg tgcaatcaag
     6901 gaacttaaac ttatagagaa aatcaaaaat ggttcctctg ttattaaaga agaggcaact
     6961 aaaaagaaag aagagttaac taaattagaa aaagaacaaa acgaagcaga ggaacaaaga
     7021 aagaaaaagg caaaagatac ggctggagaa gataggtata gagttgaatc agatgcaagg
     7081 aaatcttctt atagtggaag tagtaaaaat aataaatcta gttctaaaaa caatgataaa
     7141 aaatcagata gtaataagtc tgacaataat aacagttctt ctcaaaatca agaaaagcca
     7201 aataatagta atccaacacc agcaccaact ccacaagata ctactggtgg ttcagatagt
     7261 ggtggaaatt ctcaaaactc aaataatcaa taagtataaa atatatgcat aaatttaatg
     7321 aacaaattat atattataaa aaatatctct tagcaatttt ttcttactaa gagatatttt
     7381 ttgagaaata atttaataaa tagcagttaa attttaaact aaaaattaaa gtcacagtag
     7441 agataatcta ttgtaaacga ttatctatat atttatcaac ataagttttt acaacagcag
     7501 ctattggtac tgaaagaaaa actcctatga aaccaaatag agattgtccc accaaaatag
     7561 cagatattac ccatatagct cctataccaa cttgattacc cataactttt ggttctataa
     7621 aatttccatc taattgttgc aatataaata gaaatgcaat gacccatata gttttttgtg
     7681 gactatataa tatagtcatg gctattggag ggattgcacc aataaaagga ccaaaatagg
     7741 gaattatatt acctaagaat attattgaag ctaaaaataa agcattttct attctgataa
     7801 caaattgaaa tcctaaaaat gcaattatac caataataag agagtctaat attctaccaa
     7861 gtaaataatc atagaaaata tcatgagtag tcctaaaaaa ttctataatg ttatctgcct
     7921 tgtttctagc agtagaagaa tatagaaatc tcttaaatcc caatgcaatt ttttctttgt
     7981 catatataat gtatatggat agtataaatc ccattgtcat attaaatagc atagaagata
     8041 tactaagtgt atagattaag aagtttttag gaattttacc aacaaaatta cttgcttctt
     8101 ttaataaatt atccaaacta tgttgtatat gaggaattaa agtttttaga aaatctatgt
     8161 ttgacatatt tttttctata aaactatcta tataatcagt atacataggc atttcattta
     8221 ttaatctatt taatgtatta gctattgatg gaattaataa cctaatggca aaggctaaaa
     8281 taaaacctat aaatatataa gataaaaaaa tggctaaaag tctatgtgct ttgaatttta
     8341 cctcaaaaag catcacaagt ggatttaaaa gtaaagcaag taaaatagct aataaaaatg
     8401 ggctaaaaaa ctttaagaat ccttcaatac tagatataaa gtctgatgga gtattaataa
     8461 atttaaaaaa taaaattcca ataaacacga ctattaaata atattttata ttttcctttg
     8521 aaataataat cacttcctta aaatagtgtt tagtcagcta ttacatatta atagtatgtg
     8581 aaaagaaatt acaattattt aggaaaatta aataattttt ttgcttgttt ttaattaagg
     8641 tctagtatag tataataatg tagcaaaatt aacattgata aaaatattaa acacacataa
     8701 tttaagataa ggaaggatta agtatgagaa ttaataagta tatagcttct tgtggaatag
     8761 catcaagaag aaaagcagaa gaaataattc ttggaggaag aataaaggta aatggaagtg
     8821 tagtaaaaga gttatctttt aatattgatg aagaaaaaga catagtagaa tttgataata
     8881 aaaaagtaaa accaagtgaa aattatatat atatagtatt aaataaacca gagggatata
     8941 taactacagt aaaagaccaa ttcaatagac ccagtgtaat agacatactt aaagatgtaa
     9001 gggaaagagt atatccaata gggagattag attatgaaac tagtggttta ttaatactta
     9061 ctaatgatgg cgatttaaca tataagctta cccatccaaa acatgaaatt gataaaacgt
     9121 atgtggcaag tgtgaaggga attataagtg atgatgagat aagacaattc gaaacaggac
     9181 taaaaataga agattacaca acggcacctg ccaaaataag ggtaactaaa gaaaataaag
     9241 aaaaaaatta ttcagtgtgt gaaataacta tacatgaggg tagaaataga caagtaagaa
     9301 aaatgtgcaa agctataaat catccagttt taaatttaag aaggatttct gtggggaaaa
     9361 tagtattaaa agacaccaaa gttggagaat atagatacct aacagaagat gaaataaaat
     9421 atttaaaatc aataaaataa gataaaaata aattgagaaa aaatgaaata aagttaatag
     9481 tagggagaaa tagtattatg gcatatgcaa agtatttaac taaaattaca gatataaata
     9541 aattttattt agaaaatatt ataaatgaag gtgacatagt aattgatgct actatgggaa
     9601 atgggtatga tacaaggtat ctagctgaga aggttggaga aaagggcttt gtatatgctt
     9661 ttgatataca agaagaagca ataaagtcta caagaaagaa actagagaaa gaaggatata
     9721 cagatagagt aaaattgata tttgatgggc atgaaaaaat gaatcaatat ataaaagaag
     9781 aagtttcatg tgttttattt aatttgggtt atcttccaag agcgaaacat tcaattataa
     9841 ccaaaccaga tacaacttta aaggctataa agttaagttt agaaatgcta aaagaaaatg
     9901 gagtaataag cattgccata tatacagggc atgatggagg tcaagaagaa aaagattgca
     9961 tatataacct tgtcaataat ttaaatcaag atgaatttaa tgttttagaa tctaagtttt
    10021 taaatcaagt caataaccca ccacaattga ttttaattga aaagaaaaaa gcataataaa
    10081 tactaaaaaa cttgacaaga ttgtattaag agttaatata tatagtgtga cctattaaaa
    10141 atactttaaa taataagtat acaacagctt attctcaaaa caaaatatac atctaaatat
    10201 gcaaaataag atagataact tttaaatgag taaaaattga aaaatttaaa agaaatattg
    10261 gataaatatt aaaaaatgca aggaaagatg gtataataaa tttaatcgaa aatactatgt
    10321 gaagtataag gtacagaaaa gttagaattt tatgagttta agaagctatg ataaaaacta
    10381 agatgaaatt gagataaaaa ataaaatttt tagagaaaaa gacagtgtta ataaaacaaa
    10441 atagtttata taactaaaag gagaaaaaaa tggaagaaac aaatgaaatg aaggacagta
    10501 aacatttgat atcaaatata caatctcaat atacgagatt gagtaagggt caaaaactta
    10561 tagcacaata cattttaaat aattatgata aagttgcatt tatgactgca tgtaaattgg
    10621 gtgaaactgt aggagtaagt gagtctacag ttgtaagatt tgcaaatgca ttaggttata
    10681 gtggatatcc taaattacaa gctgcacttc aagaactcat aaaaaataaa ctaactacag
    10741 tacaaagagt tgaaatggca catgattatt ccgatgattt tgcaatacta aacaaagttt
    10801 taaaaagtga tatagataat ataaggtcta cactagaaga aattgacgag agagcgttta
    10861 aagaagcttc taacaaactt ttaagagcga gaaaaatata tatacttgga atgaggagtt
    10921 cttttgtagt agctcaatat ttaggttttt acttagatat aatacttgac aatgttcata
    10981 taattagaat ggatatggga gatgcttttg agcagattgt aagaataaat gaagaagatg
    11041 taatagttgc tattagtttc cctcgttatt ctaagaaatc ttatcaaatt gtcaattatg
    11101 ctaaggaaaa aggagcccat gtaatatcat taacagatag cttatttgcg ccagtagcat
    11161 cacttgcaga taacactctt ctagttaaga gtaatatggc ttcatttgta gattctctag
    11221 ttccagctct tagtatttca aatgcccttg ctatatctgt tgggatgaag gaaaaagaag
    11281 atattaaaca gcattttgat gatttagagc aaatttggaa aagatattct gtgtatgagt
    11341 aaagtttgta tattaataag gctatgaaat tgagaatcat agccttatta gtaaatactc
    11401 gattatcact taaaaaataa attttcgttt aaataataca aataaatatt tcgagactca
    11461 aaacataaag atgtattctg aatacatctt tactacgtca actaatttat taaagaaagc
    11521 atttccattc atggagagtg ctttttttat ttctctaaac aatatcattt ccttaattaa
    11581 caattataaa attaatttta tttgtattta agtatataat atcttattaa aattatatta
    11641 aaatatgtat ttctatcttt tttgttcact ataatatgtg tcttttagta ttttatttta
    11701 actttgacaa agaagttgaa aaatttaaaa atcatagaat tagtagttag gtatgaaatc
    11761 ttgatttttt aagtagccat ttttggggaa agggaaactt ttttagaaat ataatacttt
    11821 ataaaaataa aataaagttt ttataaatat taagacatag aatataaagc ttttg
//
LOCUS       DAMJXI010000096        11781 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.101, whole genome shotgun sequence.
ACCESSION   DAMJXI010000096 DAMJXI010000000
VERSION     DAMJXI010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11781
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.101"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            114..1154
                     /locus_tag="PC465_003369"
     CDS             114..1154
                     /locus_tag="PC465_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2650646.1"
                     /translation="MDKHSDSVMYGGMEVYNIWGTTTVDSIIGESDVMRALKNRICKI
                     GNSDSTVAITGESGTGKELIARAIHLAGNRGNKTFVAINCAAIPEPLLESELFGYTKG
                     AFSGADSKGKIGKFELANGGVVFLDEIGDMPIQLQSKLLRVLQEKKFTRIGSNELIDI
                     DVRIISATNRDLFELVKENKFREDLYYRLNVIPLEVPPLRERGDDIQILINNFIDKYS
                     RKMKKNVYHIEPDVEQMLLKYPWPGNIRELENTIELALNLLEEDGIIHKGIINRKILE
                     YFKLNNINIKLLEESDYEISMEQDILTLEEFERAYIKKVLKFYGNDTKSKKLAAKKLG
                     ISLATLYRKIDV"
     gene            1510..2832
                     /locus_tag="PC465_003370"
     CDS             1510..2832
                     /locus_tag="PC465_003370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HDF2650647.1"
                     /translation="MFDIDGRPPILKCLPLSMQHILAMIVGTVTVPIVVGGAVGVSPT
                     QITLLVQYALIIAGISTLIQLYPIGNIGSRLPIIFGVGFTYVPTLVAVGGNYGLASIL
                     GAQLIGGVATVLIGIFIKKIRKFFPNIVAGTVVFTIGLSLYPIAINYMAGGVNSPTYA
                     SMQNWAVAAITLVVVIGLSQFAKGYAKLAAIFLGIIVGYCVSLVLGIINFDPIREATW
                     FAIPKPLEFGMEFDMPVIISVVIVSIINAVQAIGDLSATTMGGMDRNITDKELSSGVI
                     GSGICTMIGALFGGLPPSSYSQNVGMVAMNKVISRFVLGIAGIFMLLSGFVPKFGALM
                     TTIPYSVLGGATISIFSMITMTGIKLIITEELSSRNITIVGLAIALGMGITSVPAAQE
                     AFPSFVKLVFGESPIVIATLVAFVLNLIIPNKSLEDEAKERAVMEETN"
     gene            3129..4490
                     /locus_tag="PC465_003371"
     CDS             3129..4490
                     /locus_tag="PC465_003371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HDF2650648.1"
                     /translation="MKTRNTSKYDVDGIPPLKESIPLALQHLLAMIVGNMVPAILIAN
                     VVGLNQGQATMLIQGSMLAAGLATFLQLYPIPLFKGFKLGSRLPVMMGMSYVFLGACL
                     SVAAKDGLAALFGAQIAAGVIVFFVGFGVKKIRHIFTPIVSGTIIACMGLGLFATAIK
                     NLAGGEGTQTFGSPINFTVGVIVAFVIIMINKYGKGLVKNSSILIGILVGYAISLVLG
                     LVDFSAVQGAAIVSLPTPAAFGLEFRPELIVMFTIIYIIGIADMMGACTIATVGAMDR
                     EVTDEELASVVLGNSITSIISSLFAALPTGVFSQNTVIVSMNKVTSRFVIALGALVLL
                     LAGISPALGAIMTTIPSCVVGGATLVVFSSIAMSGFSIMSMDGFTEENNLIAGVSIAT
                     SMGLTTAPQVLDQFPETIGTVLGGSSIVSGAIIAILLQTLFKLKSRKSAENVTSNLEE
                     NIG"
     gene            4563..5957
                     /locus_tag="PC465_003372"
     CDS             4563..5957
                     /locus_tag="PC465_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2650649.1"
                     /translation="MIDILIKNAIIVTVNKDRDVIFDGAIAIQGDRILDIGNTVDIEP
                     KYLDAKKVIDANGKVIFPGFINTHNHLFQVLLKGLGDDMALHEWLNTMMFPSAKFLTE
                     QDTYDAAMLGCMEGLKSGITTMVDYMHTHNRPGLTDGIVKAYKDLGIRGVVGRGCIDL
                     GIHKELIEDVETVEKDLRRVFEKYHNSENGRIKICVAPSSMWAISEEMGKMLWNIVKE
                     YDSYFTVHISETEFARTATKDIHGEIDIKLLEKWGIVGPEVVAVHCVCITDEDMEMLK
                     KYDIKVSHNVASNMYLASGVAPVPEMLKKGINVSLGLDGAASNNAQDMVELMKLTALQ
                     HKVNNCDPLAISAEKVLEMATIEGARTLRMEDEIGSLEIGKKADLVIFNSMLSPKSIP
                     LHNPVSTLVYSASMHNVESVLVDGNVILENGKVTTIESEEQVLLNAQHAAEELCKRAN
                     VTNRMEGHKWNSLY"
     gene            6019..6489
                     /locus_tag="PC465_003373"
     CDS             6019..6489
                     /locus_tag="PC465_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HDF2650650.1"
                     /translation="MEKIKLNINDYMYEIEVEKNETLLHVLREKLNLTGAKQGCNSGS
                     CGACKVLIDGVDMKSCKLLAKNCEGKVIYTIESFANGENLHPIQEAFIEVGAVQCGYC
                     TPGMIITTQALLNRNASPNEDEIREAFKENLCRCTGYVKIIEAVKLSAARLGGR"
     gene            6492..8708
                     /locus_tag="PC465_003374"
     CDS             6492..8708
                     /locus_tag="PC465_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2650651.1"
                     /translation="MEKVIGKSYPLKDAALKVTGQMKYVADMKPQNVLYAKMLLSPVA
                     HAKIKSIDTSEAEKVVGVRAIATYLNTSQRKYNGSLRFYEHKIPENEVIFSDTVRFVG
                     DRVAAVAAETPEIAEKAVKLIKVEYEELPAVFTIQDAIKEDAICIHGDSNIVSQNNIN
                     GGDVEKGFKECDYIFEDEYSTPAIHHSAIETHSVIAHYDYNDKLTVHTPCQNTFGFRI
                     ILSQIFGMSLNKVRVIRPAIGGSFGGKLELTIEPVAAALSKMTRRPVKMVLTRKESMI
                     STRTRHGSFVKLKTGVNKDGEVIAQDIKIYTNTGAYASSALNVIGALSHKVFKVYKIP
                     NIKFTGMPVYTNTPIAGAMRGYGSPQIFMAQQAQFAKIAKEIGMDLVDFQNKNAVEPD
                     DVDIIFHGSLGNPRVLDCIEQGKKMFKWDEKKKLPKEEGKYLRGIGMAIGAHGNGVFG
                     AHRDVVTLTLKLNEDGTLTLLTGAHDMGNGVVTMQTMMVAEVLGITPDKVDTFETDTD
                     ACTFNLGDYASRGVFVEGGGAKKTAEKLKNLILEEAEKLLETSKEDLYLDNGCVISKL
                     DENVKASLSDVAVYSQSKSLRELTVVEDYSSPAGRTSYGVHFAEVLVDKETKDIKVVD
                     FVAVHDVGRVINPLNLEGQLEGGIHMGLGYALSEELAFDEQGRPKATDFKTYKLFRTV
                     DMPKCQVAFVDGYEKAGPFGGKSIGECAVVPVAPAVANAVYNATDVEIHSLPIKLK"
     gene            8791..9462
                     /locus_tag="PC465_003375"
     CDS             8791..9462
                     /locus_tag="PC465_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2650652.1"
                     /translation="MAKILGICGSPRKGATEYAVLEALKEAETIPGIETEYWSVRGKK
                     ISPCVHCDACIRKETMCIIKDDIQELEQKILEADGIIVGSPVYDMNITAQLTAVFNRL
                     RPMYLVHPGKLQNKVGAAITTGGTRYGGQELTKLPIINFFLMHEMLVSGGLGGCYIGG
                     TIWSKDGKAKGAQEDETGMDTVKRLGKGAAEAVMVSKFGLEKWNVVKEELDVKKDEKS
                     PLRDH"
     gene            9825..11039
                     /gene="dpaL"
                     /locus_tag="PC465_003376"
     CDS             9825..11039
                     /gene="dpaL"
                     /locus_tag="PC465_003376"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HDF2650653.1"
                     /translation="MLKEIKWKVNNLPKGDKENCIKFLNEEEITKVRNFHKSFPQYKE
                     TPLANLEGLAKKLGVAGVYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAQEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNHAAAFVSAPDWVSAKGMRTLGNP
                     LNGDEKVISGESGAVTTGLLVAAMEREDLADLRKDLKLDENSRILLISTEGDTDPDKY
                     RSIVWDGEYPSI"
     gene            11166..>11781
                     /locus_tag="PC465_003377"
     CDS             11166..>11781
                     /locus_tag="PC465_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF2650654.1"
                     /translation="MLNEQRKQEVTEICQKLIQNPSSSGNEEGVVKAIEESFEKLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEGKIVDGKIYGRG
                     TSDMKGQYTAMMSAVAYFAKDTNRDFAGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGVNAVYKMA"
BASE COUNT         4453 a         1357 c         2393 g         3578 t
ORIGIN      
        1 ttttgtttta aaataatatt attaaattat aactaagctt ttctgttatg atataattaa
       61 atagataatg tgaatgatta ttatatagaa tacttatttg gagttgatat tttatggaca
      121 aacacagtga ttcagtaatg tatggtggaa tggaagtata taatatttgg ggaacaacaa
      181 cagtagactc cataattgga gagtctgatg taatgcgtgc tcttaagaat agaatttgta
      241 aaattggaaa tagtgattct actgtagcta taactggaga aagtggcact ggaaaagaat
      301 taatagcaag agccattcat ctcgcaggaa acagagggaa taaaacattc gttgctataa
      361 actgtgctgc tataccagaa cctttactag aaagtgaact ttttggatat acaaaaggag
      421 cttttagtgg agcagattca aaaggtaaaa ttggtaagtt tgaattggcc aatggagggg
      481 ttgtattttt agatgagata ggagatatgc caattcaact acaatcaaag ttattgaggg
      541 tattacagga aaagaagttt acgagaatag gttcaaatga actaattgat atagatgtta
      601 gaatcatatc agctactaat agagatttat ttgagttggt taaggaaaat aaatttagag
      661 aagacttata ctatagattg aatgtaatac ctttagaagt gcctccactt agagaaagag
      721 gagacgatat acaaatatta ataaacaatt ttatagacaa atattcgaga aagatgaaga
      781 aaaacgtgta ccatatagag ccagatgtgg aacaaatgtt gcttaagtat ccttggccag
      841 gaaatattag agagttggaa aatactatag aactggcatt aaaccttctt gaggaagatg
      901 gaataataca taaaggaata ataaatagaa agatacttga atattttaag ttaaataata
      961 taaatataaa gttacttgag gaaagtgact atgagataag tatggaacaa gacatactta
     1021 cacttgaaga gtttgaaaga gcctatataa agaaagtgtt aaagttttac ggaaatgata
     1081 ctaagtctaa aaaactggct gccaaaaaac ttggaatatc actagctaca ttgtacagaa
     1141 aaatagatgt ataataatta ggctttttat tctcaattct aaaatttgaa attataaaat
     1201 tgataaaaaa cacttggaaa actattttct aagtgttttt ttgtgtaata gcattttatt
     1261 atccaaaaat aaaaaaaatt taaaagaatt taaaaaaata aatgctttaa taaattatca
     1321 aatactaaca aatataataa aaattatata tgtaaaacaa ttatgttaaa aaattggcat
     1381 tataattgct tcatattaaa ttgagatgac aaaataaaaa aagaaaggat gttgtgtgag
     1441 ataataataa ctgtcattaa aaaatagttg ggagtgataa ccttgagtaa atatcaaaag
     1501 aatgtttcta tgtttgatat tgatggaagg ccaccaattt taaagtgttt gccactatca
     1561 atgcaacata tactagcaat gatagttgga actgttacag tacctatagt cgtaggagga
     1621 gctgtgggtg ttagccctac acaaataaca cttttagtgc aatatgcatt aataatagct
     1681 ggtatatcaa cacttataca actatatcca ataggaaata ttggttcaag attgcctata
     1741 atttttggag ttggttttac ttatgtacca acacttgtag cagtcggagg aaattatgga
     1801 ttagcaagca ttttgggtgc acaattaata gggggagtgg ctacagtatt aatagggata
     1861 ttcataaaaa agataagaaa attttttccg aatatagttg caggaacagt ggtttttaca
     1921 attggattat ctttgtatcc tatagcaata aattatatgg caggtggtgt aaatagtcct
     1981 acttatgcct ctatgcaaaa ctgggcagta gcggctataa cattagtggt agttataggt
     2041 cttagtcaat ttgcaaaagg atatgcaaaa ttggcagcaa tatttttggg aattatagtt
     2101 ggatattgtg tatctttagt tctgggtata ataaattttg accctattag agaggcaact
     2161 tggtttgcga tacctaaacc gcttgaattt gggatggaat ttgatatgcc tgtaataatc
     2221 tcagtagtaa ttgtaagtat aatcaatgct gttcaagcaa ttggagattt atcagctact
     2281 acaatgggag gcatggatag gaatatcaca gataaggaat tatcaagtgg agtaatagga
     2341 agtggaattt gtactatgat aggagctttg tttggaggtt taccaccatc atcatatagc
     2401 caaaacgtgg ggatggtagc tatgaacaaa gtaataagta gatttgtgct tggaatagct
     2461 ggtatattta tgttattgtc ggggtttgtg cctaaatttg gtgcattaat gactactata
     2521 ccatattctg ttttaggagg agctacaata tctatattta gtatgataac aatgacaggt
     2581 ataaagttaa ttattacaga agagttgtca tcaagaaata ttaccattgt tggtttggca
     2641 attgccttag gcatgggaat aacatcagta ccagcagccc aagaggcatt tccttcattt
     2701 gtaaagttag tatttggaga atctccaata gtaattgcaa cattggttgc attcgtttta
     2761 aatctaataa taccaaataa aagtctagag gatgaggcta aagaaagagc tgttatggaa
     2821 gagactaatt aagatataat aatttaaaag aattgtttaa attatttagt atgagattgt
     2881 tagattattt ttgatagcta ttcattttaa taaaaaattt aacaaataaa tatataccag
     2941 gcaattaatg ttcatttaag ttgaaaatcg gggagggaat atttagaaat ttgttaattt
     3001 tttataaaaa tagctcagtt tagctgtgtt tatcggttga gcaataaatt catggtcata
     3061 aaaatattta tagaaaataa ttataaaaat atttagtcaa gatatttatg tatgggagga
     3121 tttattttat gaaaacacgt aatacttcaa aatatgatgt cgatgggata ccaccactaa
     3181 aggaatcaat acctttggcc ttacaacatc tgttagcaat gatagtagga aatatggtac
     3241 ctgcgatatt aatagcaaac gtggtaggac ttaaccaggg gcaagcaaca atgttgattc
     3301 agggttctat gttagcagca ggtttagcaa cgtttttaca gttatatcca atacctttat
     3361 ttaaaggatt taagttaggt tcaagattac ctgtaatgat gggaatgagt tatgtatttt
     3421 taggagcttg tctttcagta gcagctaaag atggtttagc agctctattt ggagcacaga
     3481 ttgctgctgg ggtaatcgta ttctttgtag gatttggagt taagaaaatt agacatatat
     3541 tcactccaat agtttctgga actataatag catgtatggg acttggacta ttcgcaacag
     3601 ctataaagaa tttagctgga ggagaaggca cacaaacatt tggaagccca ataaacttca
     3661 cagtaggagt tatagttgct tttgtaataa taatgataaa taaatacggt aaaggtttag
     3721 taaaaaattc ttcaatatta ataggaatat tagtaggtta tgctatatct ttagttttag
     3781 gattggttga tttctcagcc gttcaaggag cagctatagt atctttacca acaccagcag
     3841 cttttggatt agaatttaga ccagagttaa tagtaatgtt tactattatt tacataatag
     3901 gtatagctga tatgatgggt gcctgtacaa tagctacagt aggagcaatg gatagagagg
     3961 taactgacga agaattagca tcagttgttt taggaaattc tataacttct ataatttcat
     4021 cactatttgc agctcttcca actggagtat ttagccaaaa tacagtaatt gtatctatga
     4081 acaaagttac aagtagattt gtaatagcac taggggcact tgtattatta ctagcaggga
     4141 tatctccagc attgggtgca ataatgacaa ctataccatc ttgtgttgtt ggtggagcaa
     4201 ctttagtagt tttctcatca atagcaatgt ctggtttctc tattatgagt atggatggat
     4261 tcactgaaga aaacaatctt atagcaggtg tatctatagc aacaagtatg ggtcttacaa
     4321 ctgctccaca agttttagac caattcccag aaacaattgg aactgtcctt ggagggtcaa
     4381 gtatagtttc tggagcaata atagctatat tacttcaaac attatttaaa ttaaagtcac
     4441 gtaaaagtgc tgaaaacgtt acttcaaatc ttgaggaaaa tattggataa atgtattaga
     4501 tataatatga gaaaaccata tggtaaaatg ttgtaatgaa agtattcaaa gggggattta
     4561 agatgattga tatactaata aaaaatgcaa taattgttac agttaataaa gacagagatg
     4621 ttatatttga tggagcaata gctattcaag gtgacagaat cttggacata ggaaatacag
     4681 ttgatattga gcctaagtat cttgatgcta aaaaagttat agatgctaat ggaaaagtaa
     4741 tattccctgg ctttataaat actcataatc acctgttcca agtgttatta aaaggtttag
     4801 gtgatgatat ggcacttcat gagtggttaa atacaatgat gtttccatca gcaaaattct
     4861 taacagaaca agatacttat gatgctgcaa tgcttggatg tatggaaggt ttaaaaagtg
     4921 gtataactac aatggttgat tatatgcata ctcacaatag accaggactt acagatggaa
     4981 tagtaaaggc atataaagat ttaggcataa gaggggttgt aggtagaggt tgtatagatt
     5041 taggtattca caaagagctt atagaagatg tggaaacggt tgaaaaagat ttgagaaggg
     5101 tattcgaaaa atatcataat tcagaaaatg gaagaataaa aatctgtgta gctccttctt
     5161 caatgtgggc tatatctgaa gaaatgggta agatgctttg gaatatagtt aaagaatatg
     5221 attcatattt tacagttcat atatctgaaa cagaatttgc aagaacagca acaaaggata
     5281 tacatggaga aatagatata aaattacttg aaaaatgggg tatagtaggt ccagaagttg
     5341 tagcagtaca ttgtgtatgt ataactgatg aagacatgga aatgcttaaa aagtatgaca
     5401 taaaagtttc tcataatgta gcaagtaata tgtatcttgc ttctggtgtt gcacctgtgc
     5461 cagaaatgtt aaaaaaaggt ataaatgtga gtttaggtct tgacggtgca gcaagtaata
     5521 acgcacaaga tatggtagag cttatgaaac taacagcttt acaacacaaa gtaaataatt
     5581 gtgaccctct ggcaatttct gcagagaaag ttcttgaaat ggctacaatt gagggagcaa
     5641 gaactcttag aatggaagat gaaataggtt ctttggagat tgggaaaaaa gctgacctag
     5701 taatatttaa ctcaatgctt tctccaaaat caatacctct tcacaatcct gtatcaactt
     5761 tggtatactc agctagtatg cacaatgtag agagtgtttt agttgatgga aatgtaatac
     5821 ttgaaaatgg aaaagtaact acaattgaaa gtgaagaaca agtgttgctt aatgcacaac
     5881 atgcagcaga agaattatgt aagagagcta atgtaactaa tagaatggaa ggacataagt
     5941 ggaatagctt atactaatat taaaataaga ttgtaataat attctattac aacattagtt
     6001 tatctgtagg aggagaaaat ggaaaaaata aaattaaata ttaatgatta catgtatgaa
     6061 atagaagttg aaaagaatga aactcttttg catgtacttc gtgaaaaatt aaatctaact
     6121 ggagcgaaac aaggttgtaa tagtggcagt tgtggagcat gtaaagtttt gatagatgga
     6181 gttgacatga aatcttgtaa acttcttgca aaaaactgcg aaggtaaagt tatatacact
     6241 atagaaagtt ttgctaatgg agaaaatctt catccaatac aagaagcttt tatagaagtt
     6301 ggagctgtac aatgtggata ttgtactcct ggtatgatta taacaacaca agctctttta
     6361 aatagaaatg catctcctaa tgaagatgaa attagagaag cttttaaaga aaatctctgt
     6421 agatgcacag gatatgtaaa gattatagaa gctgtaaaat tatctgcagc tagattaggg
     6481 ggtagataat tatggaaaag gtaataggaa aatcataccc tctaaaagat gcagctttaa
     6541 aagttactgg tcaaatgaaa tacgtggctg atatgaaacc acaaaatgta ctttacgcta
     6601 agatgctttt aagccctgta gcacatgcaa aaataaaaag tatagataca agtgaagctg
     6661 agaaagtagt aggtgttaga gctatagcta cttatctcaa tacatcacaa agaaaataca
     6721 atggttcatt aagattttat gagcacaaaa tacctgaaaa tgaagttata ttttcagata
     6781 cagttagatt tgttggtgac cgtgttgcag cagtagctgc agagactcca gaaatagcag
     6841 agaaagctgt aaaacttata aaagttgaat atgaagaatt gccagctgta tttactatac
     6901 aagatgcaat aaaagaagat gctatctgca tacatggaga ttcaaatata gtttctcaaa
     6961 acaacataaa tgggggagat gtagaaaaag gcttcaagga atgtgactat atatttgaag
     7021 atgaatactc tactccagca atacatcata gtgcaataga gactcatagt gtaattgcac
     7081 actatgatta taatgataaa ttaactgtac atacaccttg ccaaaataca tttggattta
     7141 gaataatact atctcaaatt tttgggatgt cattaaataa agtaagagtt ataagacctg
     7201 ctattggagg ctcatttggt ggaaaattag aacttacaat tgaaccagta gcagccgcat
     7261 tatcaaaaat gacaagaaga ccagttaaaa tggttcttac aagaaaggaa tctatgatat
     7321 caacaagaac tcgtcatggg tcttttgtaa aattaaaaac tggtgtaaat aaagatggtg
     7381 aagtaatagc acaagacata aaaatatata caaatacagg agcatatgca tcaagtgctt
     7441 taaatgttat aggagcactt agtcataaag tatttaaagt ttataaaata ccaaatataa
     7501 agtttactgg gatgcctgta tatacaaata caccaatagc aggagctatg agaggctatg
     7561 ggtcacctca aatatttatg gctcaacaag ctcaatttgc gaaaatagca aaggaaatag
     7621 gtatggattt agtcgatttt caaaataaaa atgcagtaga gccagatgat gtcgatataa
     7681 tcttccacgg ttctcttgga aatcctagag tattggattg tatagagcaa ggtaagaaga
     7741 tgtttaagtg ggatgaaaag aaaaaacttc caaaagaaga aggaaaatat ttaagaggta
     7801 taggtatggc aataggtgca catggtaatg gagtttttgg tgcacataga gatgttgtta
     7861 cattgactct taaattaaat gaagatggta cgttgacact actaacagga gctcatgata
     7921 tgggtaatgg tgttgtaact atgcaaacaa tgatggtagc tgaagtttta ggaataacac
     7981 ctgataaagt tgatacattt gaaactgata cggatgcatg tacattcaac cttggtgact
     8041 atgcaagtag aggggtattt gtagaaggtg gaggagctaa aaagacagca gagaaattga
     8101 aaaatcttat attagaagaa gcagaaaaat tacttgaaac atcaaaagaa gatttatatc
     8161 tagacaatgg atgtgtaatt agtaaacttg atgaaaatgt aaaagcatca ctttctgatg
     8221 tcgcagtata tagtcaaagt aaatcattaa gagagttaac tgttgttgaa gattattctt
     8281 caccagctgg acgtacttct tatggtgtac attttgctga agttttagta gataaagaaa
     8341 ctaaggatat aaaagtagtt gattttgtag ctgtacatga tgttggtaga gttataaatc
     8401 ctctaaattt agaaggacaa ttagaaggtg ggattcatat gggtctagga tacgcattga
     8461 gtgaagaatt ggcatttgat gaacaaggta gacctaaagc tactgatttt aaaacatata
     8521 aattatttag aactgtagat atgccaaaat gtcaagttgc atttgtagat ggttatgaaa
     8581 aagctgggcc ttttggtggt aagagtattg gagaatgtgc cgttgtacca gttgcgccag
     8641 ctgttgcaaa tgcagtatat aatgcaactg atgtagagat acattcatta ccaataaaat
     8701 taaaatagta gaaattaaag cagaaataac aatttattgt atttgtaaat agataataaa
     8761 aatagattta tttggtgagg agatattatt atggcaaaga tattaggtat ttgtggaagt
     8821 ccacgtaaag gagcaacaga atatgcagtg ttagaagctt tgaaagaagc agaaactata
     8881 cctggtatag aaactgagta ttggtcagtt agagggaaaa aaataagtcc ttgtgtacat
     8941 tgtgatgcat gtataagaaa agaaactatg tgtattataa aagatgatat ccaagaatta
     9001 gagcaaaaaa tattggaggc agatggaatt atagtaggtt ctccagttta tgatatgaat
     9061 ataactgctc aacttacagc agtatttaat agacttcgtc caatgtattt agttcatcca
     9121 ggaaaacttc aaaataaggt tggtgcagct ataactactg gtggaactag atatggtggc
     9181 caagaattga caaaacttcc tataataaat ttcttcctaa tgcatgaaat gttagtgtct
     9241 ggaggtttag gtggatgcta tataggtggt acaatatgga gtaaagatgg aaaagcaaaa
     9301 ggtgcccaag aggatgagac aggtatggac acagtaaaaa gacttggaaa aggtgcagca
     9361 gaggcagtta tggtttctaa gtttggtctt gaaaaatgga atgtcgtaaa agaagaatta
     9421 gatgttaaaa aagatgaaaa atcacctctt agagaccact aaagatttat tatattattg
     9481 aatatataca aatagtgatg taatagatta ttgcatcact attttatgtt ttaatttaga
     9541 ttttataaat tttatattaa aaaatataga aacaaagtgt tttgagattt atttttaaat
     9601 tttaaaaatg agaattaaaa agtgagaaga tagaaaaggt tttttagtta ttaaattcta
     9661 catacattgt atgaactaaa gatagaaaag aaaaaataat aaaagcattg caatttctat
     9721 actaaagagt catggaaaaa tatctagtat atatttagta ttggcatgtt aattgcttat
     9781 atattaaagt ataaaaattt aacaataatt tggaggtatt ttagatgtta aaagaaatta
     9841 aatggaaagt aaataatttg ccaaagggcg ataaggaaaa ttgtatcaaa tttttaaatg
     9901 aagaagaaat aactaaggtt agaaattttc acaaaagctt tcctcaatat aaagaaactc
     9961 cattagcaaa cctagaaggt ttagcaaaaa aattaggtgt tgcaggagta tatgtaaaag
    10021 atgaatctta tagatttgga ttaaatgcat ttaaagtatt aggtggttct tattctatgg
    10081 gtagatactt agctcaaaga ttagatacag atatatctga gttagggtat gacaaattaa
    10141 cttcaaaaga aataaaagaa aaattaggag aaataacttt ctttacagct acagatggaa
    10201 atcacggtag aggagttgct tggacagcta ataaattagg tcaaaaatct gttgtattaa
    10261 tgccaaaagg ttcttctgaa tttagattaa ataaaattaa aggagaaggt gcagatgcta
    10321 gtataacaga cttaaactat gatgatgcag taagattagc taatgattat gcagaagctg
    10381 atgaccatgg agtaatggtt caagatacag catgggacgg atatgaagaa ataccagcgt
    10441 ggataatgca aggatatgga actatggctc aagaagctat agagcaatta aaagaatatg
    10501 gagtagatag accaacacac gtatttgttc aagcaggagt tggttcactt gctggtgcag
    10561 ttcaagggta tgttgcttca atatatgatg aatgcccaat aacagtagta gtagaggctg
    10621 acgaagctga ttgttactat aaatcagcag aagctggaga tggaaaacca agatttgttg
    10681 gaggagatat gccaactata atggcagggc ttgcttgtgg agaaccaaat actataggat
    10741 ttgaagtatt aaaaaatcat gcagcagcat ttgtttcagc accagactgg gtttctgcta
    10801 aaggtatgag aacattaggt aatcctttaa atggtgatga aaaggtaatt tctggagaat
    10861 ctggagcagt tacaactggt cttttagtag cagctatgga aagagaagat ttagcagatt
    10921 taagaaaaga tttaaaatta gatgaaaatt caagaatact tttaataagc acagaaggag
    10981 atactgaccc tgacaaatat agaagtatag tttgggatgg agaatatcca agtatataag
    11041 gaattactaa aatgcaatta ttagatattg gtttacatat ttagaagata tataagttct
    11101 aaaatttaga aaatatataa gtatataaaa tacatacatt ataaaaaatc tagggggata
    11161 atgaaatgtt aaacgaacaa agaaaacaag aagtaactga aatatgccaa aaattaattc
    11221 aaaatcctag ttcttctgga aatgaagaag gtgttgtaaa agcaatagaa gagtcttttg
    11281 aaaaattagg ttttgatagt tggtcaagag atagatatgg aaatatagta ggatgtataa
    11341 aaggtaacaa gccaggtaag aaaatcttat ttgatggaca tatagataca gttccagttc
    11401 cagatgcaag taaatggagt gttcctcctt ttgaaggaaa aatagttgat ggaaagatat
    11461 atggtagagg aacttctgac atgaaaggtc aatatactgc aatgatgtct gctgtagcgt
    11521 attttgctaa agacactaat agagattttg ctggagaact atatgtagca ggtgttgttc
    11581 atgaagaaat atttgaaggt gtttcagcta gagagataag taaggctgtt caacctgact
    11641 atgttgtaat aggtgagtct tcagagttaa acttaaagat tggtcagaga ggtagaggag
    11701 aaatagtagt agaaactttt ggtaaaccag ctcactctgc taatccagaa aaaggtgtaa
    11761 atgcagttta taaaatggct a
//
LOCUS       DAMJXI010000097        11021 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.103, whole genome shotgun sequence.
ACCESSION   DAMJXI010000097 DAMJXI010000000
VERSION     DAMJXI010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11021
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.103"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(38..670)
                     /locus_tag="PC465_003378"
     CDS             complement(38..670)
                     /locus_tag="PC465_003378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HDF2650655.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
     gene            complement(742..1095)
                     /locus_tag="PC465_003379"
     CDS             complement(742..1095)
                     /locus_tag="PC465_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HDF2650656.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKPQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNVLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            complement(1173..1376)
                     /locus_tag="PC465_003380"
     CDS             complement(1173..1376)
                     /locus_tag="PC465_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDF2650657.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDVI"
     gene            complement(1766..1996)
                     /locus_tag="PC465_003381"
     CDS             complement(1766..1996)
                     /locus_tag="PC465_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2650658.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINGILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            complement(2000..2404)
                     /locus_tag="PC465_003382"
                     /pseudo
     CDS             complement(2000..2404)
                     /locus_tag="PC465_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897392.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
     gene            complement(2764..3213)
                     /locus_tag="PC465_003383"
     CDS             complement(2764..3213)
                     /locus_tag="PC465_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2650659.1"
                     /translation="MELIEWNYAYITELVEFANDKEIANNLRDNFPHPYREQNARDFI
                     SFCLATPDVKQLSYAIFYQERAIGSISLTFEEDTSINKNAELGYWLARNYWGKGIATN
                     AIKEICKIAFEKYNLNKIHANVYSYNRGSSKVLEKCGFKIEEYCHNS"
     gene            complement(3227..4153)
                     /locus_tag="PC465_003384"
     CDS             complement(3227..4153)
                     /locus_tag="PC465_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650660.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESNLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKISVKQGNETVEIADG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            complement(4278..5060)
                     /locus_tag="PC465_003385"
     CDS             complement(4278..5060)
                     /locus_tag="PC465_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HDF2650661.1"
                     /translation="MTKTQQKMIQNVLEFSKRDSRIIGLAISGSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDSPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYACTKIGRR
                     ELFETIDFLSFLRQSVLAPLIQLLLGKLPRGVRKIELDAPQYIEALEKTVANHEYKSC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            complement(5216..5836)
                     /locus_tag="PC465_003386"
     CDS             complement(5216..5836)
                     /locus_tag="PC465_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF2650662.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            complement(5924..6487)
                     /locus_tag="PC465_003387"
                     /pseudo
     CDS             complement(5924..6487)
                     /locus_tag="PC465_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729092.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            6723..7538
                     /locus_tag="PC465_003388"
     CDS             6723..7538
                     /locus_tag="PC465_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF2650663.1"
                     /translation="MVKLSDAKSWAIRMSEDGCAYKSIGNYKRSLKASFFMAIQDDCI
                     RKNPFNFQLSDVLEDTTEPKIALTPEQEMGLLSFMESDKTYCKYYDDVVILLETGLRI
                     SELCGLTLELDMKNKAIMVDHQLLSDTKIGYYVEVPKTTQGKREIPMTERAYQSFERI
                     VERRKNAKAEPIIVDGYQNFLFLKQDGLPKQATHYQSMLRALVKKYNKTHEDKLPKIT
                     PYIFMHTLCTNMANKGMSPNILQYIMGHKNITMTLGYYAHGSFSSARAEMERL"
     gene            8210..8977
                     /locus_tag="PC465_003389"
     CDS             8210..8977
                     /locus_tag="PC465_003389"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDF2650664.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(9305..9982)
                     /locus_tag="PC465_003390"
     CDS             complement(9305..9982)
                     /locus_tag="PC465_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650665.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(10132..10449)
                     /locus_tag="PC465_003391"
     CDS             complement(10132..10449)
                     /locus_tag="PC465_003391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2650666.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            complement(10471..10809)
                     /locus_tag="PC465_003392"
     CDS             complement(10471..10809)
                     /locus_tag="PC465_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2650667.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
BASE COUNT         3660 a         1735 c         1563 g         4063 t
ORIGIN      
        1 attaaagtaa agtttaatat aaataaatta taaaatatta aactaattta tcaatatttc
       61 ctgattgaat atgcttaatg tttgattgaa tttttttata tggccaatcc caccatttaa
      121 tttctaataa ttttgaaatt gtatcattat taaatctctt ttttataatt tttgcaggta
      181 ctcctccaac aatagaatac ggtgggacgt cattagtaac tactgctctt gttccaataa
      241 ttgcaccatc accaatattt acacctgaca taattataga atcataacct atccacacat
      301 catttccaat tataatgtta cccttattgt cccaagcgtc cgttatatgg ttgatatcga
      361 gtttccattc ttcataaaag atgggaaaag tatatgtgga ttttgatttc attgagtgat
      421 ttccactagt cattagaaat tttgcattac atgctattga gcaaaactta ccaattatta
      481 atttatcatt gtttataggg taatgataca atacattgtt tttctcaaaa tctcttgggt
      541 cattataaaa gtcattatat attgtgtaat ctccaacttc tatattttcc cttgttatta
      601 catttttaag atatacagtt tgataatcat tacttcttgg atatacctta tttgaacttg
      661 gaatagtcat atttaaatct ctcctttaat atatattatg tttttgacta ttccactact
      721 acaatacatc tcttcacaga atcactcctt gttaagaatc ttcataagat aatggcgtcc
      781 ttttttagtg ttaagtcgga tattctttct tagtacattc tttttagcgt ataactgaca
      841 aactgtcatt ttcttaccaa tagtgtcaat gctatcatca aggtcatttt gtattgcttt
      901 ttccttatcc cttaatgata tatcatcacg ttttcccttt gggggtttat cagtaggtac
      961 aagtttccaa gagtaaacaa attgtggttt accaaatgaa tatacatact tatatgcgta
     1021 tcttccatct tttctctggc tctctccagt tcttaaaatt ctatctttat tatctcgtct
     1081 tttttcagtt gacatgataa gaagctcctc tcaataaccg aattgagctt gatacgtcat
     1141 atgaatatta taacatataa ggctcaattt cattagataa cgtcaagtgt atcaacgatt
     1201 ttctcaaatt gttttctctt tatttgaatg cgattgctat tcataatgac ccagccagaa
     1261 tcaaggtttt catcagcaag tttacgtaat tttttctctc caatacgaaa gtattttgac
     1321 gcttcttcaa tcgtcaaggt atatttttcc caaataggta catcagtatt gttcatagaa
     1381 tgtatcactc ctttctatgt tcgtagttca gaagtagata gatggctttg gtaagctcca
     1441 ttggtatttc aaccaatccc attcttatgg gcagaaccgt gtcatacagg tgtatcatta
     1501 tactgtggta caggttacgg caaaacaacc gttccaaagg ttattcacaa atcactatat
     1561 agtagctctc ttgattaagg tcatggcgta tagtatttgt tggctatctg tatcacaaac
     1621 gtatctatct actttattca gttgtcaaag aacagtcggc attgatttgc ctataaaaaa
     1681 tcacaatagc ttgtgggctt ttatagacaa ataattagtg attctccatg taccaaatag
     1741 cttgatacat ggagagaggg cgagattaag acaaattaaa tctcaaaata gcagtgatta
     1801 gttttgttcc tagcattcgc tttgtttctt cttctacatg aatataggga tttccgtatt
     1861 catcaaataa agttttctgt gaaagacgaa tgatatagtg ttcaaaatgt ttaagtattc
     1921 cgtttattgc atttacatcg ccatgtacag caagtaaaat aattgtaaaa ggtaatactt
     1981 ctttagtagg tttcatttca tgttcctcca tgagttcttt caactctttt agtgcatttg
     2041 ttttgtgata atgtatggta ttttctgcta aatccatcaa tgttgctatg tcagcatttg
     2101 tcatgttgag aaagaatgaa agtagaatta tatcttgttt tctttttgta agttttccga
     2161 ttgcttgtgc cattaataca tcttcaattc gtatgttgta gtcgtaagaa accatacaga
     2221 tgtagttaga atcataatca tctaaaatac tcaatttact taattctgca agtgacaaag
     2281 attcgagaga taccaaataa tcatttctgc gtttattttc gtcataaata tctctagcat
     2341 agttacgcaa aactgtttta cagaaactgt cgaattgatg ttcaattgtc ttttcatcaa
     2401 ccataagatt tcaccctctt tccatcgcaa ggagttaaat aaccttgctt actcctatca
     2461 cggtgggagg gaattaaatc ttcgataaat ttcaaaaaaa agagaaaaaa atacacactc
     2521 tgcctatagg gcaaaaatgt gtattcttta aaacgtattt aatttatatt ggttgtaagc
     2581 caccaccata ttgatgtatg gaaatatgca ttggctagct tttcataaaa atacaaagat
     2641 gcataagaaa ttaatagagg ggaaaaactt attctgttat taaaaagtag gttaattcta
     2701 ataaatgcta ttgcggtcga attaaactat atacatggca atcaatcatg tttctattct
     2761 ttattatgaa ttgtgacagt attcttcaat cttaaaacca catttttcca atactttact
     2821 tgaccctcta ttgtaggaat atacattagc atgaattttg ttaaggttgt atttttcaaa
     2881 ggcaattttg catatttctt ttattgcatt tgttgctatc cctttgcccc aatagttcct
     2941 agcaagccag taacctaatt cagcattttt attaatagag gtatcttctt caaatgttag
     3001 gctgatactt ccaatagccc tttcttgata aaaaatagca tagctaagtt gtttaacatc
     3061 tggagttgcc aaacaaaaac taataaaatc tctagcgttt tgctccctat aagggtgggg
     3121 gaagttgtca cgaagattgt ttgcaatttc tttatcattc gcaaactcaa ctaactcggt
     3181 aatataagca taattccact ctataagttc catttttctt ctccttttat gaaacagcta
     3241 caagaaatct ttctaagcca ataccactta tcaaacagcg ttctttttta tttccaagca
     3301 tttgataagt ccagtcaaca aatccaccgt cagctatttc aacggtttca tttccttgtt
     3361 tgaccgatat tttgaaattg atacctttat aataattatt atcaacatca tcattatgaa
     3421 ttgataactc tatattagga aaaataagtt tgatagtttc aaccattctg tcgaaaaatc
     3481 cgtcattatc tttgtatccg tttcttttgc gtagaataat agagaaacga acattttcta
     3541 tttcacttaa tatatcttta taatagttta agtgcttttc taacaacatt ttttcacaag
     3601 tgtaagaccc tgtatctata ccagatgaaa ccatacaata taagccaaaa tgtgaatata
     3661 aacctttacc tacaaaattt tgtgctctta ttaccctagc agtagtagcc atgtggatag
     3721 gtatggtatt attttcttct tttcttttta atttatcagc aataattatt gccaacatat
     3781 ttgaggggtc tgcaagtgtt tctgtccctc gtagagcact tactacgtta tattgatcta
     3841 cggagccaaa aacgctacag ctacctaatg gggcagaggg agaaagcata atcgtcttga
     3901 tatccatatt gaatgctttt ctcaataaat ttgattccaa agcatgaatt tcttctggat
     3961 ctataccgct agggatagta aatctattta gttggtatga ctttagaata tcagttgcag
     4021 ttaaagtatt tgcttgtcta tcaaacactt ctaatagaag tgagttcaaa tctgattttg
     4081 atagagctga taacttatca actatattct tatccccaat tttatttgta attctactta
     4141 aaatatcact catagttatc ctccatactg ttactttcaa aataattata gaattgttac
     4201 aacaactaat ctaggtcatt tgaccaaaaa tgaaaaaaca ctgaatattt actattcaat
     4261 atttttttac tttgggttta tttgattaaa tcttgaaaat actgtaatgc aaccctttca
     4321 gcttcaacct ttcggacaat aggactttgt gataattcct ctcttaactc aagatacagg
     4381 ttgatagtag cctgcaatgc attaacacag cttttatatt catggttagc aaccgtcttt
     4441 tctaatgctt caatatattg gggtgcgtcc aattcaattt ttctaactcc acgaggtaat
     4501 ttacctaaga gaagttgtat taatggggca agtactgatt gtcttaaaaa agataaaaaa
     4561 tcaattgttt caaatagttc tctacgtcca atcttagtgc aagcgtaatg aacccaaatc
     4621 caaaatctat cttcaatcca ctgtaagtct ggagttggga agtatgcttc ttttttagaa
     4681 taaatttctg ttatgcagtt gttttcttca tagagaatag ctgaatcttc aaccctatct
     4741 agtaaaccat ctaaggttgt aaacttaaaa tcaacatgaa gaacagggga atcatagagg
     4801 gaaattatca atcgaggttc tccaacatgt tcgccagtaa aagcagaaac taatgttcca
     4861 aactgttcca caataagtaa tctctcttcg ataacttctt cataggattt atcatctgct
     4921 acaatcagaa aatccaaatc agaatattca tctaacgatt ttgtgatata agaaccgcta
     4981 attgcaagtc ctattatcct actatctctt tttgaaaatt ctaatacgtt ttgtatcatt
     5041 ttctgttgtg ttttagtcat aatataacac ctctcactgt cttttattag ctatcaatcc
     5101 aacataatta tgcataggag tattatataa tgaagaaata aaaaaaaata ggtcacttga
     5161 cccgaaataa aaaagcattg aataattatt attcaatact tttttgaaat tatacttatg
     5221 ttgtaggaag attctttaat acctctcgct gattaattac actaaatctt ttgttttcat
     5281 aagcaattag atgttcttgt acacattcat ttatagcacg attaatgctt ctaattggag
     5341 cgtttacttc gctagcaagc tgttttttgg taagcagatt taattcactt ctataatagt
     5401 gtaaggatat acacctcaga agtcgttctt taacacttaa agatgataat tcttcaatta
     5461 attcagcatt tacaactaat ttactagata tttctcgaat cagaaatttt gtagcttcaa
     5521 aatctcccct taaccagttt aaaaaatcat ctctatgaag tttatataca ttacaatctg
     5581 tgaaagcgac aatttcaacg ggttttttcc catcattaaa ttgttccatt tctccaaaaa
     5641 aactaccact tctataaaga tgaatcgttg agatgtttcc tttcacattt aagatgaatg
     5701 cttctgcaat accgtcaatc ataagaatta catattcatt ttcttgctca gcaaaaagaa
     5761 tagtctcttt ctttttatac gtttttttaa caagcttctt tttaatatct tcattcataa
     5821 aatcaattaa atgcatattc atccctcctt accaaatctt tgattaaatt atatcatctt
     5881 tcaattagtt aggtaagata gtaaaaatat atttacatag aaactattcc attattattt
     5941 tccagttgtc atttttctgc aaaaacttat cactgtcacg actggagata ccagtaagaa
     6001 atgttaggat atcaatcgct aaactttcag aatccttttt acggctcaaa atgacgtaat
     6061 ggtcaagcaa tcctttgttt tcatcatcac tggttaaatt gacaatgttt atctcatggg
     6121 ctatttctgg tagcgtttct ttccatttgc cgcgttttgc tttagggtca actatgaccg
     6181 cctatccgcc gaatagtacc gcatagtaaa caagcatatt gttactgaat aatttaccac
     6241 cacccaatga accgataaac gcagacgcta acgcattggt aatagaaccc tttacccctt
     6301 gactagcaag ggcaggtttt agatagacat tctttccagt gtccagattg tagctaacat
     6361 agatatcctc atgttcgcca agggtttgtg tcgctccaaa accaagtcca gccaaaaaat
     6421 ccgaagtgac atattgaata taatcattga tgtaacgttt gctgacagga ataaattcgc
     6481 catgcaatcc caacatatcc ccaaagggat gcacgagctt gattgataag tcgtcgtaaa
     6541 agtctttgac ttcatcacaa tgccttttta gctcgtcaag atcctttgta gatacacgga
     6601 caacatagct aagtttatac atagattctt tacagttaaa agtctgtttt taaaaaaatg
     6661 tataaattat aaatcaaaat atagatacta tcaatgaccc actaggtgca aaaagcattg
     6721 atatggttaa attatcagac gctaaaagct gggctatccg aatgagtgaa gatgggtgtg
     6781 cttataaatc cattggcaat tataagcgct cactgaaagc gtcgtttttc atggcaattc
     6841 aagacgactg tattagaaag aatccattta attttcagtt aagtgatgtt ttggaagata
     6901 caacagaacc aaaaatcgct ctaacaccag aacaggaaat gggcttatta tcctttatgg
     6961 agagcgataa gacttattgt aaatattatg atgatgttgt tatcctctta gaaacaggac
     7021 tacgcatttc tgaattatgc ggtttgactt tagaattgga tatgaaaaat aaagccatta
     7081 tggtagacca tcaattgttg agtgatacta agattggcta ttatgtagaa gttccaaaga
     7141 ccacacaggg taagcgagaa attccaatga ctgaaagagc ttatcaatca tttgaacgta
     7201 tcgttgaacg gcgtaagaac gctaaagcag aaccaatcat tgttgatggt taccagaact
     7261 tcctatttct taaacaagat ggattaccaa aacaagcaac tcattatcaa agcatgttaa
     7321 gagcgttagt caagaagtat aacaagaccc atgaggacaa gctaccaaag attacgccat
     7381 atatctttat gcatacactc tgtacaaata tggctaacaa aggaatgagt cctaatatat
     7441 tgcaatatat tatggggcat aaaaacatta ctatgacgct tggctattat gcacatggtt
     7501 catttagttc tgcgagagct gaaatggaac ggttataagc ctagtagtat gactagagtt
     7561 tactacttat ttactacttt tgatggcatt cttatacggt taaatgccaa cttatgcaaa
     7621 gtatcttcca aaaagaaaat gtcgatactc cttgtagata caggatatat cgacatttac
     7681 caacttatga aaagataatc aaatttaata taagtttttc aaataaaaag atactaaatt
     7741 ctttttcgag aatctatata acattactta agcttggttg gggtataaac aattgagtag
     7801 ctacttttgt atggtgttca actttagtca aaactcttaa ataatgcaaa tgatttagat
     7861 tcattaatat tcaatctctt cataagtagt gaaattcgag ttatttctgc ataattatac
     7921 tatgatttat agattaattc tattagcatc cagaataata ttgtttatat gaataaaatt
     7981 taaagaatat tatgaaaatt ataggatgtt aaaataaatt taggtaaaaa agaagtgttt
     8041 gtatattata gagtaccttt tctaaaatat gtgggattgt tttaagaatt agaataaaaa
     8101 ttatttttaa attagtattt ttataatgta tagtattttt aatgtataat taaattgtgc
     8161 agaaaataga atttaaagtc ctatagaatt tctgattatg gaggagaata tgaaaagaaa
     8221 agttcaagta aaaaatatta ctattggaga aggtagacct aaaatttgtg taccaattat
     8281 tgggaaaaat aaaaaagata ttataaaaga ggctaaagag ttaaaagatg catgtttgga
     8341 tattatagag tggcgagttg atttttttga gaatgtagaa aatattaaag aagttaagga
     8401 agttctctat gaattaagaa gttatataca tgatatccct ttattattca catttagaag
     8461 tgtagtagaa gggggagaaa aattaatatc aagagattat tatactactt tgaataaaga
     8521 aatttctaat acaggtttag tagatttaat agatgtagag ttatttatgg gagatgaggt
     8581 catagatgaa gtagttaatt ttgctcataa aaaagaagtg aaagtaatta tatctaatca
     8641 tgattttaat aaaactccaa aaaaagaaga gattgtatct cgtttatgta gaatgcagga
     8701 attgggcgca gatttaccca aaatagctgt tatgccgcaa aatgaaaaag atgtgttagt
     8761 gctacttgaa gctacaaatg aaatgtttaa aatttatgca gatagaccaa taataacaat
     8821 gtcaatgtca ggaatgggtg ttataagtag attgtgtggt gaaatatttg gttctgcatt
     8881 gacttttgga gctgcaaaaa gtgtttcagc accagggcaa atatcattta aagagttaaa
     8941 ttcagtactt aatctattac ataagagtat taattaaatt aattatatag aaatattaga
     9001 cggtattttt gaagatataa attaaatata aaaaactttt cagatagtaa aatttaaatt
     9061 gggcaattat atctgaaaag caactattta gtgtgtattt tgaaagtgat atagaaaatc
     9121 ttataaatca actatggcat atttaaaata tgccattaaa acctactaga cattagatta
     9181 tagatggtat actagcattt ctattattta tagatagtaa gttttcataa taactgtttt
     9241 atctaaagta gaagatatat ttgtattatg tatatttgtc attatttttt tgtaattatg
     9301 tatattaatg gttatatatg taatataata ttatcactct attttttgta tattgtacat
     9361 tacaacattt atatctatca tcatcaatta cagtagaatg tatgggatac ttattttcac
     9421 ttaaccaata tttttgcata ttctttgtcc aagactttgg aaacttcaat actttcttgt
     9481 ttattataac atcctcatct tcaaaaatat taacttctct ttctattttt atttttctgt
     9541 tgtatatctt attgatagat tctttgtcga gttttatgtc tctatacata tcagggcaat
     9601 agcaacaaac ataatttctt ttttttcgac gtttaaattt cacaactttc tctatgctaa
     9661 tttctaattt ttttgtacca tcttttataa atttaatatc ttctatgttc tcgcttgaaa
     9721 aaatttctgt caatcttaaa gtatctacag tttctctaat tatttgcttt ttataagaag
     9781 agaatccata tccaaaagaa aggtttaatt tattagggat gtagccattt ttatatttaa
     9841 acatcttaat tttttccaat tcagcattat ctttaaattt caacttttca tacctaaaag
     9901 ttactttgct aaaaagagta tattctacat caatatattc ttttgcaatc ttaaatttat
     9961 cgctaccttc aatcacaatc atagcctatc tccaatcgtt ttatattaaa ataaggccat
    10021 agaacatggt ctaatagtac tcattagcac tataagacaa tgttaacaca aaaagacaaa
    10081 aaaaggttat ttatttcaaa taaccttttt ttttatataa aatataaaga attatatttt
    10141 attctttttt atgatgtcta taatctgtga tatcagattt agttctcttg aatttaagtc
    10201 ttttaactct tcatttatat cattttctaa atatgttttt ccagtggaag taatatcttt
    10261 tataagaaca tctgcagaaa tatttaatat atttacaaat tttatgaatg ttttaagact
    10321 tggattcttt ttaccacttt cgatttgagt tatataccaa ggcgatactc caaccatatt
    10381 tgcaaattct tttgaagtta aatttgcttt tttccgttct tctttaagtc ttttacctat
    10441 ataattcatt attgttacta tttccctcac ttatatttct ttgtatttaa tgatgcactt
    10501 tattaactct agcattgcaa tttgttcttt ttcagttaat ttattaatca tttcataaca
    10561 ttctaaaggt acagagttat caacgccttc tgttgtaata atatttgcaa ataacaattc
    10621 aagtggtatg tctaaagcag tagcaatttt cattataata ttgatagatg tatttgtctc
    10681 agctctttca atctgaccaa tatatgttgg atgtaaacct gccttttctg ctagaaactc
    10741 ttgactatat cccaattttg ttctatagac ttttattcta tctcctatta tttttcctat
    10801 atttgccaat tattatccct ccactttaga ttatattcat agtttaagtt gttttatata
    10861 gactatttat acttttttag tctaaatata gactatatat gtttttatac tgaaataagt
    10921 gctatttatt tttgtatagt ctgtatctac aataaacaaa tatggataaa tcatattttt
    10981 aattagagaa atattttcat aatttcatag ccatactaca a
//
LOCUS       DAMJXI010000098        10867 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.104, whole genome shotgun sequence.
ACCESSION   DAMJXI010000098 DAMJXI010000000
VERSION     DAMJXI010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10867
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.104"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(204..536)
                     /locus_tag="PC465_003393"
     CDS             complement(204..536)
                     /locus_tag="PC465_003393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HDF2650668.1"
                     /translation="MNTREMKEYRVFYNKKLSETDEFFRVFGSLDDKTYSEGAISKKN
                     KELMGLAISILSRCDECICYHIEGCINSGASKDEIIEAIKIGVIGGGSITYPNARFAI
                     KILEEFNI"
     gene            complement(780..1421)
                     /locus_tag="PC465_003394"
     CDS             complement(780..1421)
                     /locus_tag="PC465_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HDF2650669.1"
                     /translation="MKKAINKQFILSTLICFIPFIVSIYFYNRLPNEVAIHFDNYGNP
                     DNYAPKVIAAFGVPLLMLCIHLYTWFRLENEPKKANFSNVIQNLSKWGVAILSVIIQI
                     MMVLYSTGVSLESNFYTGLILGIIVILFGNYLPKCKRNYSVGIILPWTLNDEDNWNKT
                     HHLAGWIWLIGGILLIINAFINIPFYNIFVIFVIVILPFIYSYLMYKISGKNN"
     gene            complement(1402..1695)
                     /locus_tag="PC465_003395"
     CDS             complement(1402..1695)
                     /locus_tag="PC465_003395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2650670.1"
                     /translation="MGFPETFKALSDPIRREILVMLRENKMSAGEISEKFNMTNATIS
                     YHLSQLKKAGLIFETKYKNFIFYEINISVFEEVMLWFSQFMEKGEKDNEKSDK"
     gene            2088..2138
                     /locus_tag="PC465_003396"
     CDS             2088..2138
                     /locus_tag="PC465_003396"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650671.1"
                     /translation="MTEYIYYYNNKRIKKN"
     gene            complement(2664..3416)
                     /locus_tag="PC465_003397"
     CDS             complement(2664..3416)
                     /locus_tag="PC465_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HDF2650672.1"
                     /translation="MFSVIFLCIGGFLAAFVDSIAGGGGLISMPVLMAIGVPVHLAIG
                     TNKFAASAGCISSAYRYAKSGKINNDLLKKLVPFTIIGSVLGVRCVLSISEEILNVLV
                     VVMILIVAIYTFISKNLGQEDNFEAVNKKNLRLGMLMALIMGFYDGFFGPGTGTFLTF
                     GFIKIYGYDFLHASANTKILNLTSNITSLLLFMINGQVDYKIAIVFALVMIMGAYVGA
                     KVAIKKGSKMIKPIFLVMALFMVVKLVYQTLV"
     gene            complement(3475..5130)
                     /locus_tag="PC465_003398"
     CDS             complement(3475..5130)
                     /locus_tag="PC465_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2650673.1"
                     /translation="MVDFIESNNEVQKFDWGEVMWIHEPSKTQFNRLSAGIVRFFPGN
                     CQEKHFHLSEEQLLYVIQGEGIQIIDGKKVNIKETSIVYCPPYSEHEIINTGKIDLVI
                     LITYVPHKFSSLRQIPIVFSENNIQELVNVNIIENLANQISNILKLRISVYDLKYKEI
                     FETKKENKFCDICKNIKQCTKKLVKSINNDNFEKVYHCEYGVSSLEIPIVLEENIVGY
                     IECGNFIVYKSIDIDKNLSELSSSSGIDIKYINKIYNEFPLNPKSRLYVLKENLLMMS
                     EFIQEIAKRNFFENQLSIKDEEILKSRKENIRLEEALKKANSRLLEEEYIINPIDMFN
                     NSSKEYPFELELYIEKEIKNMNLEGVYNLIDTNKLRYNDVRDTIQEMIFVLSRTVLRD
                     LEDLKLISYLRNKYNKKISLVNSDEDLWNVLFEFSKECIDKNRAFWRKDKGNLIENIN
                     EYIKKYYKENINLNSISDVFFISPNYLSSIFNERNKVSITEYINLLRIEESKKYLLDR
                     SMSISDICKKVGFNNSSYFSQIFKKFNSITPNEYRKNMLDNKY"
     gene            complement(6403..7487)
                     /locus_tag="PC465_003399"
                     /pseudo
     CDS             complement(6403..7487)
                     /locus_tag="PC465_003399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897145.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            complement(7571..8227)
                     /locus_tag="PC465_003400"
     CDS             complement(7571..8227)
                     /locus_tag="PC465_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2650674.1"
                     /translation="MTRKNNPKQAIENIITISAKLFAEKGYDKTSMQNIVDASGMSKG
                     GIFHHFSSKEDIFNVVMERRFEQIIETVNQWLGEMHGLTAKEKLRSLVRRHLTDEVIK
                     ESSNMITSAIESPHIILAFTQDNLKKLAPILANVLREGIEDRSIITEFPDECAEVILL
                     LFNFWCDTDVFQGDFPTLRKRFQFLQFLMRQIGVDILEDEIIESINIFYERKPMGQVE
                     "
     gene            8549..8755
                     /locus_tag="PC465_003401"
     CDS             8549..8755
                     /locus_tag="PC465_003401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650675.1"
                     /translation="MISHAAEICKKYKMPFIIFPTIEKKSIEEWVNIGANMLCFAQDT
                     TFITYVINQLLSFYNEIVPIQKQH"
     gene            complement(8908..9336)
                     /locus_tag="PC465_003402"
     CDS             complement(8908..9336)
                     /locus_tag="PC465_003402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDF2650676.1"
                     /translation="MSKIYIVYWSGTGNTEKMANFVAEGVKLKGKTPEVLDVSLLKPS
                     DLKEEDKFALGCPSMGAEQLEEGYMEPFVSELESMVSGKQIGLFGSYGWGNCEWMRDW
                     EERMQNAGATIIGGEGITAMEDPNEEAKDECIELGKTLAE"
     gene            complement(9812..10750)
                     /locus_tag="PC465_003403"
     CDS             complement(9812..10750)
                     /locus_tag="PC465_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HDF2650677.1"
                     /translation="MNKRMKLIPYEINENLRGAKNKFPYGIKQMNARGMWDEGYTGKN
                     IVVGIIDTGCDISHPLLKGKIIGGANFSDDSNGNKNIYEDFNGHGTHVAGIIAASNYN
                     NEVMGVAPDCKLLIAKALNKDGTGTYQSIINAINFAVNNKVDIISMSLGGNKDDKKLK
                     NAVMQAVKNNISVVCAAGNNGDGDSSTSEYSYPASYAEVIEVGAINENYLVEKFSNSN
                     TTIDLVAPGRNIISTYMDNKLAIMSGTSMSAPYVSGSLALIKEWAREEFERDLDEAEL
                     YAQLIKCTRALGIPRTEQGNGYLYLNLYKYKNNGKR"
BASE COUNT         3624 a         1931 c         1134 g         4178 t
ORIGIN      
        1 ataaaagatt taataatgac aatatactat tctcaataca atctatgatg taaataattt
       61 aaaactacta tattatttaa aaatttatat ttatatatgc aattctaaaa acttaataag
      121 aagtgaactt agaaaataaa gcttaatttc aaagacttaa atagactatt attattagtc
      181 taaataaact acgtctatca aaattatata ttaaattctt ctaaaatttt tattgcaaat
      241 cttgcgtttg gatatgtaat agacccgcca ccaattacac ctatttttat agcttctata
      301 atttcatctt tacttgctcc agaattaata caaccctcaa tatgataaca aatacactca
      361 tcacatcggc ttaaaattga aatagctagt cccattaatt ccttattttt tttacttata
      421 gccccttctg aataagtctt atcatcaaga cttccaaata ctctaaaaaa ctcatctgtt
      481 tcgcttaatt ttttattgta aaatacccta tattctttca tttctctagt attcatcttc
      541 tacctcctat gtttttctta taagaatatc acactgtact tatattttca atattaaata
      601 caaattttca ttttatgttc attagcctaa tttatattat tttttgaaat ctcaataagt
      661 tatcatataa gtaagatttt ttcagaacta aaatagaaat cttagtaatt tctttattac
      721 ctatctcagt tctgaaatat attattctta tccaaacatt attatattga ttaattatat
      781 tagttatttt tacctgaaat tttatacatc aaataagaat atataaatgg tagtattaca
      841 attacaaaga ttacaaagat attataaaaa ggaatattaa taaatgcatt aataattaat
      901 aatattccac caataagcca aatccatcca gctaaatggt gtgtcttatt ccaattatct
      961 tcatcattca gagtccatgg caaaattatt cctactgagt aatttcgttt acatttagga
     1021 agatagtttc caaataaaat aactattatt cctaaaatta atcctgtata aaaattagac
     1081 tccaaactaa ctcctgttga atataaaacc atcattattt gtataattac tgaaagtata
     1141 gcaactcccc attttgataa attttgtata acatttgaaa aattagcttt cttaggctca
     1201 ttctcaagtc taaaccatgt atacaaatgg atacatagca ttaacaatgg tacaccaaaa
     1261 gctgctataa cctttggagc ataattatct ggatttccat aattatcaaa atgaattgca
     1321 acttcatttg gtaatctatt ataaaaatat attgatacaa taaatggtat aaaacatatt
     1381 aaagtagata aaataaattg tttatttatc gcttttttca ttatcttttt ctcccttctc
     1441 cataaattgt gaaaaccaaa gcataacctc ttcgaaaact gaaatattta tttcgtagaa
     1501 aataaagttc ttatactttg tttcaaatat gagtcctgcc ttttttagtt gagatagatg
     1561 ataagaaatt gtagcattcg tcatattaaa tttttcacta atttctcctg ctgacatttt
     1621 attctccctc aacataacca atatttctct tcttataggg tctgaaagag ctttgaatgt
     1681 ttctggaaac cccaacacca tcacctcgct atttagaatt tcatctaaat agaatataac
     1741 ataacatcca ttttatttca atagctattt agaaattttt ctaaatagtt atttctaaat
     1801 atttattgaa aattttcata ttaagattct caatttactt aagtcgcttt tatttaatct
     1861 tactttatct aattttttta acttaacaaa agtgtattgc accataattg ttaaagcaaa
     1921 aacctaatga ctgaggtact tatatatata acaatacttt taattttaaa ttaaaagtag
     1981 ctaaacccaa tttaaaaagt agttaagtcc tatttaaata gaaaagaatg aaacgagaaa
     2041 tatactgtat aaaagtacat aaaaacatct actaattaga tacaactata acagaatata
     2101 tttattatta taataacaaa agaataaaaa aaaattaatt tagcataacc ttgttaaata
     2161 tagatttgaa tatgaattta aagttatgta aaattaaaaa tacaggaatg aaaattccat
     2221 tcctgtataa aatctaactt ttgagtctca gtacaatctt attttgagac aatctttttt
     2281 gttttatatt ttcttatatt taaaatataa cgcatatctt atgcaacata ttcatatttt
     2341 tctttatatt ctttcatcgc atcattccaa gcgtcttgta ctgttacacc tcttttatta
     2401 gcaatttttt gtgccagttc aattatcttc atagctcttc ttgatatgtt cataaacatt
     2461 cctcctacaa attaccatat atttcatata tataaatcaa ggttatattt ttatgatata
     2521 taatccttct attgtaagat tacagtttat atgtgtatta tatatgaact atattagaag
     2581 ataattagaa tttttataaa gctatatgat tagattaaat ataaaagctt tacaattact
     2641 tataaattta aaaagtctat aagctaaact aatgtttgat ataccaattt tacgaccata
     2701 aataatgcca ttactaaaaa tattggtttt atcatctttg aacctttctt tatagcaact
     2761 ttagcaccta cataagctcc cattatcatc actaatgcaa acactatagc aattttataa
     2821 tctacttgac catttatcat gaataataac aatgaagtta tattacttgt taagtttaat
     2881 atttttgtat ttgcagaagc atgtaaaaaa tcatatccat atatttttat aaatccaaag
     2941 gtcaaaaaag ttcctgtacc tggaccaaaa aaaccatcat aaaaacccat tataagagcc
     3001 ataagcatcc ctagtcttaa atttttctta ttaacagctt caaaattatc ttcttgacct
     3061 aaatttttag aaataaaggt gtaaatagcc actattaaaa tcataaccac aaccaaaaca
     3121 tttaatatct cttcacttat tgataataca catctcacac ctagaacact accaataata
     3181 gtaaatggta ctaatttttt taaaaggtcg ttattaattt ttccagactt tgcatatcta
     3241 taggcactac ttatacatcc tgctgatgct gcaaatttat ttgtaccaat ggcaagatgt
     3301 actggcactc caattgccat aagaacaggc atgcttataa gtcctcctcc tcctgctata
     3361 gaatctacaa aagcagctaa aaacccccct atacataaaa aaataactga aaacataaaa
     3421 ttcctccatc attctctttc aatttttctt acaatatata ttatataatc ttatttaata
     3481 cttattatcc agcatattct ttctatattc atttggagtt atactattaa acttcttaaa
     3541 tatttgtgaa aaataactac tgttattaaa acctactttc ttacaaatat cactaatact
     3601 catgcttcta tctaacagat attttttaga ttcttctatc ctaagaagat ttatatactc
     3661 agttattgaa actttatttc tttcattaaa aatagaactc aaataatttg gacttataaa
     3721 aaaaacatct gatatactat tcaaatttat attttcttta taatattttt ttatatattc
     3781 gtttatattt tcaattagat ttcctttatc ttttctccaa aatgctctat tcttatcaat
     3841 acactctttg gaaaattcaa ataatacatt ccataaatct tcatcactgt ttacaagtga
     3901 tattttttta ttatatttat ttcttaaata agatataagt tttaaatcct ctaaatctct
     3961 aagcactgtt ctagacaata caaatatcat ttcctgaata gtatctctaa catcattata
     4021 tcttaatttg tttgtatcta ttagattata aacaccttct aaattcatat ttttaatttc
     4081 tttttcaata taaagttcta attcaaaggg atattctttt gaagaattat tgaacatatc
     4141 tatcggatta ataatatact cttcttctaa taatctacta tttgcttttt taagtgcctc
     4201 ttcaagtctt atattttctt ttctactctt caatatctcc tcatctttta tactaagttg
     4261 attttcaaaa aaattcctct tagctatttc ctgaataaat tcagacatca ttaataaatt
     4321 ttcttttaat acatataacc tacttttagg atttaatgga aattcattgt aaattttgtt
     4381 tatgtatttt atatcaatac cagaactact tgataattca gataaatttt tatctatatc
     4441 aatagactta tatactataa aattaccaca ttctatatat ccaactatat tttcttctaa
     4501 tactataggt atctctaaac tggaaacacc atactcacaa tggtacactt tttcaaagtt
     4561 atcattattt atgcttttaa caagtttttt agtacactgt tttatatttt tacaaatatc
     4621 gcaaaattta ttttctttct tagtctcaaa tatttcttta tactttaagt catatacaga
     4681 tattctaagc ttcaatatat tagatatttg atttgcaaga ttttcaatta tgtttacatt
     4741 aactaactcc tgtatattgt tttcagaaaa tactataggt atttgtctca aactcgaaaa
     4801 tttatgagga acataagtaa ttaatattac taaatcaatt ttaccagtgt ttataatttc
     4861 atgttctgaa tatggtgggc aataaactat agatgtttcc tttatattga cctttttacc
     4921 atcaattatt tgtattcctt ctccctgaat cacatataaa agctgttctt cacttaaatg
     4981 aaaatgcttt tcttggcagt ttcccggaaa aaatcttaca attccagcac taagtctatt
     5041 gaattgtgtt tttgatggtt cgtgtatcca cataacctct ccccaatcaa atttttgtac
     5101 ttcattattt gactcaataa aatccaccat aaactcacct cgtagttttt gtctaaatat
     5161 tttttcttcc cttcttatat taaaataata tcatcatcat taactttcat tactataaaa
     5221 tcatcatact cttttaatac tcctgtaatt ttagttgcac ttagtttact acaattcagt
     5281 tttttaatat attgataaat tctataatta cttttttatt ttgtaaaatc agtgttttcc
     5341 caaaataatt atatctataa atgaaagtat ttttactgct tacatcaata tatgttatca
     5401 taattttcct ttttattgca tatataaata actgtatata acattgtcca atactatata
     5461 gaaatacatc taagaaagaa tattattaaa ttgttccaat tagtattatt tttcttataa
     5521 aaataaaaaa actgttggat tcttttagaa aaattatttt ttacatacct tttttgctta
     5581 gatagtctat cttctcagct attttgtata tacactcttc tagttcatga ttttatttta
     5641 atatcttgct tatattgctg aaataattga attcttttat ctatcatatt gtctcttata
     5701 tcataaacat attgtttctt atatcacaaa aatgaaagca ttcttatatc ttcaatatat
     5761 aaacctgctt tttttaatct tgtaataaat ataggatact ctatattctc ttcctagaaa
     5821 taactaatac cacttatttt tctattatat agaaagtaat aaatcttttt cttaataaaa
     5881 ttcaatagta agtggaataa aattttatat gaataagaac attataaaaa tactttatac
     5941 aatagtcaat aaaagatatt agcttcaaat tatgttaaag ttgtattatt taaagtgaaa
     6001 aaacaaataa aaaagaaata atagtataag tagaaaaata tacttaaaac aaggcgaagc
     6061 ctctcttgta tctaaatcaa gtagagaatt aaatctaaaa aagaaaataa atataaaaga
     6121 tgactcctgt acattacaag aatcatctta tggtttcata atcactccat ggtttttaac
     6181 tgtctgatat aaaggtctca gttcactcat agcatgacca ccctttccga ttgctgaccc
     6241 cgtcacttat ggacaaaatg tccataagtg atagtcctct cttaaaaccc tctaaataga
     6301 tatatctcaa gcacctcatt gaaaccagtt gctggaaaca aactgaagcg ttctggaata
     6361 gtaaaagaaa ttgccaccat atccacgtta ctgtcctagt tgttactttg ctaacttcgg
     6421 agcaatttcc tctaacaata cgcagtcaaa ttctgccttt ttgctaagaa atggcagatg
     6481 gtctgcatct ggtataaaaa aaatctgttt gtctggcgcc actatttcat caaaaaattt
     6541 cttcgctgga agataggggc tattatagtc attttctccc atgatgtagt atacagggac
     6601 ctgatagtca actccataat ttcttatgtc agcttcttcc actaaaaacc gcaatacatc
     6661 accttgattg tcaatcgcat ttggattgac aatggccgta ttttttaact ctctcaatga
     6721 ataatacggg gttgccagta tactgattat attgcccaaa tccatattta tagaaagccc
     6781 atacttgctt tggtatgttc ttactgtcat aagagctgcc aaatagcttg gaccatattt
     6841 tgctggcgga tatggtgcaa tagcttccag cgccttgata tctttttgct tccctgcagc
     6901 tttcaccatt tcaagtgtct tttcatagcc cacgcgctca ttgtccacca tattaacggt
     6961 ctgcgcaatc ccaatgtacg cgctgtaatc ctccggatag gtttgcacag ccatagttcc
     7021 cagcactgtt ccccagctat gacctataag gataattttc tccttgttga actcttgctt
     7081 caaatatgct gtcacctcat ggacgtcttg cagaacacgc tccgcgctca tggtctgcaa
     7141 aactgctgcc ggatcgttcg gttcgcaaag tatgttttgc ctacgtttcg ctgatcccag
     7201 ttcaccacag taaaatcatt ttcccactca tactggtaca gatgtaaaaa tggcatcatt
     7261 gaattaccag gacccccatg aacccaaagg atgatggggt tgtctgcgtt ttgtccccgg
     7321 atatataacg cctgctgtat gccgccgatc tccaccattt ccatgcggtc gattccagga
     7381 gcttctattt tatggcttgt acgtataatc gtgggggcta tcagacgcaa accggcaaac
     7441 gccagaacaa aaacagcaac tagtatgcaa agtgtgatta atatcatttt aagtaccttc
     7501 tttcatgaat ttttttagcc atagatatct cctctaacat taaaaaaaat atgttgctat
     7561 tttagttttg ttactctacc tgtcccattg gtttcctttc ataaaaaata ttaattgatt
     7621 ctataatctc atcttccagg atatcaactc ctatttgtct cataagaaac tgtaagaatt
     7681 gaaaccgttt acgaagtgta ggaaagtccc cctgaaatac atctgtatca caccaaaagt
     7741 taaagagcag caaaattacc tctgcgcatt catctgggaa ctctgtgatg atgcttctat
     7801 cctctatgcc ttctcgtaaa acatttgcta atattggtgc tagttttttc aaattatcct
     7861 gtgtaaatgc cagtatgata tgcggacttt ctatagcgct tgtaatcatg ttactagatt
     7921 cttttatcac ctcatccgtt aaatgccgcc taactaaact tctaagcttc tcttttgctg
     7981 taagtccatg catttcaccg agccattgat ttactgtctc tattatctgt tcaaagcgcc
     8041 tttccatgac cacattaaaa atatcttctt ttgaactgaa gtgatgaaaa attccgccct
     8101 ttgacattcc cgaagcatca acaatatttt gcatacttgt tttgtcatat cctttttcag
     8161 caaacaattt tgcagaaatg gtaatgatat tttcaatagc ttgctttgga ttgttctttc
     8221 tagtcattat ataactcctt cttattaaaa accgactgtt ggtttttatt atataagcta
     8281 ttcctacttc tgtcaagcaa cattatgttt atggcaaaac aataaggttt ggtggttaga
     8341 caggtattaa ttagactaat gcgactttcc cctagatgga acccttggta aatttgcaat
     8401 ctttaccggc tttgattata tctgtaagca aggcaggtat ggccacacct gccctgtttg
     8461 accctcggat attcattcct atccctcctc tccttagcca ttacaccaaa acgccgctca
     8521 ttgtctccaa tggcggcgtt ttaaagatat gatttctcat gctgctgaaa tatgcaaaaa
     8581 atataagatg ccctttatta tttttcctac aatagaaaag aaaagtattg aagaatgggt
     8641 taatattgga gcaaatatgc tttgttttgc acaagatact acctttatca cttatgttat
     8701 caatcaatta ttatcttttt ataatgagat tgtaccaatt caaaaacaac attaaattat
     8761 aaatctaatt ttatattaaa agagactaat attttatcta tctctattaa ggatattttc
     8821 ttatgtatca taatattagt ctctcttatt attatatact gctatcatca ttagttgcta
     8881 tttatactat ttttataata tacaaattta ttcagctaac gttttgccta attctataca
     8941 ctcatctttt gcttcttcat ttgggtcttc cattgctgta attccttctc caccaataat
     9001 tgtagcacca gcattttgca tacgttcttc ccagtctctc atccattcac aatttcccca
     9061 tccatatgaa ccaaataatc caatctgttt acctgatacc atagattcta attctgaaac
     9121 aaatggctcc atatacccct cttctagttg ctctgctccc atagatgggc aacctaatgc
     9181 aaatttatct tcttctttta aatcacttgg tttcagtaag ctcacatcta aaacttctgg
     9241 tgtcttacct tttaacttca caccttcagc cacaaaattt gccatttttt cagtatttcc
     9301 tgttccactc caataaacaa tatatatttt actcattttt acctcctgta gtatttttta
     9361 attaatcaat agttagttat agctaactaa catctaaaaa acaaaagatt tctttatctg
     9421 aaatctcttt atttttctaa atatagaata tcatagttga ttttgaaatt caatacttat
     9481 tgataatgtt tatcatttat attttatatt cattttataa tatcaaaaca ctgtatcgta
     9541 tttctaatct ttcatagaaa aatttctaac ttatagtact tttgcatctc ttataaatct
     9601 tttatatgta taagtacata gaaaaacaca ccttttccag atgtgctatc tataatatcg
     9661 tatatttatt tttcaattct aactagctaa tatgtttata aattttatca cttaatacct
     9721 ttatacattg atgtaaaatc ttacacctaa gtaattttta ttatttatct cgactctata
     9781 taatatagct attttatcat caaatcaaaa attatctttt gccattattc ttgtatttat
     9841 aaagatttaa atataagtat ccatttcctt gttccgttct aggtattcca agcgctctcg
     9901 tacattttat taattgtgca tatagttcag cttcatctaa atctctttca aactcctctc
     9961 ttgcccattc tttaattagt gctaatgagc ctgatacgta tggtgcactc atactggtac
    10021 cactcataat agcaagttta ttatccatat aagtcgatat aatatttctt cccggagcta
    10081 ccaaatctat tgtagtattt gaattactaa acttttcaac caaatagttt tcatttattg
    10141 cacctacttc tattacctca gcataactgg ctggataact atactcactt gtactagaat
    10201 caccatctcc attattacct gctgcacaca ctacagaaat attgtttttt actgcttgca
    10261 tgacagcatt ttttaacttc ttatcatctt tgtttccccc aagagacata gatataatat
    10321 caaccttgtt atttacagca aagttaatag cattaattat actttgatat gttccagtac
    10381 catctttatt taatgctttt gctattaata atttacaatc tggagctact cccataactt
    10441 cattattata gttagatgca gctataatac ccgccacatg agttccatga ccattaaaat
    10501 cctcatatat atttttattt ccattactgt catcactaaa atttgcacca ccaattattt
    10561 ttccttttaa aagaggatga gatatatcac aacctgtatc tattatacca actacaatat
    10621 ttttaccagt ataaccttca tcccacattc ccctagcatt catttgtttt attccatatg
    10681 ggaatttatt ttttgcacct cttagatttt catttatttc atacggaatt agtttcattc
    10741 ttttattcat catatatcct cctaaaaatt ttattgctta taaaaatcat gaattttatt
    10801 ttataatagg tttataaatc aaattaaaac ctatatctac ttatttatat ttatgatata
    10861 tttttta
//
LOCUS       DAMJXI010000099        10716 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.105, whole genome shotgun sequence.
ACCESSION   DAMJXI010000099 DAMJXI010000000
VERSION     DAMJXI010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10716
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.105"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(555..1298)
                     /locus_tag="PC465_003404"
     CDS             complement(555..1298)
                     /locus_tag="PC465_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HDF2650678.1"
                     /translation="MNFLSDLHTHSIVSGHGYSTLLENINYCKENGIKILGTSEHGPK
                     MPGSPHKWYFHNIQNIPRIINNIIILRGCEANILDIKGNIDLEPFVIPRLDYLILSFH
                     EAVFSPNTLENNTKALINAINKHDNIEILGHLGNPNYPIDYELIIKLAIEKNILIEIN
                     NCSIKGVSRNGSSDNCKYIATLCKKYGAKIILTSDAHICFDIGNYEYSENILKEINFP
                     DELIMNYPKKLINHFHQKGKLLDVDYTNI"
     gene            1464..4031
                     /locus_tag="PC465_003405"
     CDS             1464..4031
                     /locus_tag="PC465_003405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2650679.1"
                     /translation="MTQKKLSRKEKVLICLKRLTEEHLNFNNGIRFGFDAEYIATEVG
                     INRSNASKELNQLIKESIIIKIKGKPVQYLYKESIESILGKKLNKGIFDNINSINEYS
                     ENDSIKDEYILESIKKENNIFNLVGCDGSLRSQIEQAKAAVIYPPKGLSTLIIGPTGV
                     GKSIFAEYMYKYSLTIKEDSDNAPFIIFNCADYSDNQQLLLAQLFGYVKGAFTGADKD
                     KYGIVHEANNGVLFLDEVHRLSAEGQEMLFLLMDKGIYRRLGEANKVHECRVMIIAAT
                     TEDPETAMLETFLRRIPVTIKIPSLEERGFQERMKLICYFFKEESVRIGVKLKVSKEV
                     IKAFILYKCKGNIGQLKSDIQLICARAFLDYMTYKRECVYVRLSLLPNNIRESLYGNN
                     RKEEFVQNFSFIGKDDIIFLPEEKDFESENLLIENKKYDLDFYGMIKETWNKLQQEGI
                     KESQIRSVIDGDIQKYSYNLMNTFIYNSSNQTAYNNIVNDSIATTVKYILQKHDKWSK
                     REGLDKLIKAIALHIQNLIERIKIGNIVKHPNKDEIMKERAYEYNIAKEILSNMSLMY
                     GVEFPEDEAIFLATFLYLSYVGLNEESIAILVIMHGESTASSMVNVANTLLDCNHAVA
                     INMGLEDRVQDILVQAVEIANKIDKGKGILILTDMGSILTFAKVIRDATGKEVKAIDM
                     VSTPIVIEATRKALTPEMTLEKLYFNIIESIKKHYGDMEVTYAEKDNGGRYFDRLLID
                     NISKTLTFLNGEKAYFILKEVINRISEHYSLVIQDELLVKFIFHCSCMIERVIIKESL
                     VYKSYEERISRNKELYLVIKESFKLVEETFDIIISDMEYANILDIFESQYDTDKFKS"
     gene            4261..4665
                     /locus_tag="PC465_003406"
     CDS             4261..4665
                     /locus_tag="PC465_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2650680.1"
                     /translation="MIGIIVMTHGSFSEEIIKSCELIAGPAERTAAIKLNRNDNIEDL
                     NKNFVEKLNELDEGDGVLVLADLLGGSPSNVASLNLKKGGKFHALTGVNLPMLLEALI
                     NREGKSLEELAEACIEAGQTGINNINKVLSSM"
     gene            4689..5186
                     /locus_tag="PC465_003407"
     CDS             4689..5186
                     /locus_tag="PC465_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2650681.1"
                     /translation="MSLVKYCRCDDRLIHGQVIYKWVKHLGVKKIVVVDDETTNDVIA
                     KGLIKMAAPKNIDLSILTVSESRRYFYNNQADDNVFVLIKNLDTANRMIEEGINIKKL
                     IVGRIPTGIGKKKISQNVYINKKEFLLIDEFIKKNINVSIQMVPDEEEVELNQNINRY
                     KGEFI"
     gene            5189..5590
                     /locus_tag="PC465_003408"
     CDS             5189..5590
                     /locus_tag="PC465_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HDF2650682.1"
                     /translation="MNKYKVIILCHGTWGKVLVEETNKNFGLSNQYEVLSLSSEKDVS
                     VFMKEVEEVVDKEDVKIIISDLYGGSTSSVAIAVAIRRGIDAINGLSLQTILIVDEEL
                     SKEDKLHTLPERIVKKNNNLCVDLIKEFKKI"
     gene            5608..6096
                     /locus_tag="PC465_003409"
     CDS             5608..6096
                     /locus_tag="PC465_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2650683.1"
                     /translation="MAKITLVRVDHRLIHGQVITKWVKIAQAQKIIIVDDFLGQDEFM
                     ADIYKMAAPSGVEVVILTAEDAGQAFQNNTLGDKNIFILFKNVDMANKAYKAGLKYEK
                     IQLGGIPNEAGKKMVFTAVSLGNEDVEQLNELNENGVEIVLQVIPEESSMTYENALKK
                     FK"
     gene            6123..6878
                     /locus_tag="PC465_003410"
     CDS             6123..6878
                     /locus_tag="PC465_003410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2650684.1"
                     /translation="MESVLMLAIVTGLWYWFAAGLAGYTLFSTLKSPLFIGFSLGLLW
                     GDVTTGMIVGASIEMVYLGMVAAGGNIPSDKCLAALIAIPVALQTGVNAEVAVSIAVP
                     LGVIGVLVNNLRRTGNAVLVHKADKYAEEGNTKGIWRCATLYSLIFGFVLRFPIVFVC
                     NFFGADLVQSLLDVIPQWLMNGLTVMGGILPALGFATTIFTIGKNKFLPMFIIGFFMV
                     QYFEISITAAAIFGVCIALLITFMKEDKRVGEV"
     gene            6878..7741
                     /locus_tag="PC465_003411"
     CDS             6878..7741
                     /locus_tag="PC465_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2650685.1"
                     /translation="MQEIKNKEVKNGQGPTEVNKTRVLTKKDVTKTYLRWWWTAELSN
                     SFERMQALAVCASFTPALEKLYKRKEDLVDALKRHLQFFNTQAIWGGLIHGTVLAMEE
                     EKATEGKIPGEVISGVKNGLMGPLAGIGDTLDFGTFQTIFLALGASFGAEGSVIGAFF
                     PIMFSILLFCEGYYLFHLGYSLGRDSIKKILSGGIVNKIIDGASILGMFMMGALSATT
                     VKLSTPLSFDIGGKAIVVQDTLNMIAPGLLPLGVVFFVYWGMKYKKWTITKLLVILVV
                     LALVGSFIGIF"
     gene            7788..8267
                     /locus_tag="PC465_003412"
     CDS             7788..8267
                     /locus_tag="PC465_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-amino-thiazoline-4-carboxylic acid
                     hydrolase"
                     /protein_id="HDF2650686.1"
                     /translation="MSEKMYTEKEYLEGIRGATGERAVWFYLLMKEAEKLGANPDDIC
                     KEAIYGFGKMRGQKYNVADTPGKMAEMLYNSKGQKVFEMELVENTDENGVLKFHHCPL
                     DAAWKEYGLTKEERKEICRLACYGDYGRVDCAQGVKLDFAQKCAHDDEVCELVFTKK"
     gene            8332..9639
                     /locus_tag="PC465_003413"
     CDS             8332..9639
                     /locus_tag="PC465_003413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2650687.1"
                     /translation="MDISRSVDNSLNRTIEFLKELIKIDSQQGEPISQCPFGIGPKKS
                     LDKTLDYCASLGFSVKNIDNYIGYAEIGEGEELIGIPMHLDIVPPGEGWSVDPFSGAV
                     IDNIIYGRGVIDNKGAVSMLIHVLKNIEDMYPTINKRIRLIFGTNEETGMKCIKYYLD
                     KGEEIPSMGFTPDAMYPVVNGEKGRVHIRIEKEIKIDKSKPYIIVRGGTKENVVPSHC
                     TAKIINGIISELTTKGVAVHASNPEKGENAISKMVIKIVEDNMDFQHREDIELVSKYL
                     CSDYYGDALGINQYDEVFKNTTLNLGILKVNEEKIVCELDIRYGKNIVLNNIIDRFKK
                     VFCNGWKIEVIAHKDLHYVDESNLVLKKLLEAYEEVTDENGYTIAMGGGTYASWFKDM
                     VAFGPKFLAYKTGGHGVDERVPINHIRKNMEIYTLALIKLLEL"
     gene            9949..10089
                     /locus_tag="PC465_003414"
     CDS             9949..10089
                     /locus_tag="PC465_003414"
                     /inference="COORDINATES: protein motif:HMM:NF021468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2185 domain-containing protein"
                     /protein_id="HDF2650688.1"
                     /translation="MNGEGCILSNKITKECYKVGYMIREKSIDTYPDSGWGFMTWDEN
                     GE"
     gene            10599..>10716
                     /locus_tag="PC465_003415"
     CDS             10599..>10716
                     /locus_tag="PC465_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2650689.1"
                     /translation="MNELNIAKTLILKRKEKGITQDELANYIGVSKASVSKWE"
BASE COUNT         4217 a         1043 c         1983 g         3473 t
ORIGIN      
        1 taaatttaaa tatttagaga taagctatta tagaatttgc ttagtttaag ttaaatttta
       61 aaatattcaa aaaggggcta gagtctggaa atttttattt aaagaataca cataaaaatt
      121 tctagactct catcatttaa aagaagtatt ctaaatttat tatttataat taaatattat
      181 ctgaaaaaat ggtattttta tacctttgtt tgttatgcat aattttactt agaacataag
      241 ctttatataa aataattaaa aatataccta attaaaataa gtaaaaaaag agctatcata
      301 gaacaaattt aatttgctca tgtgacagct cctttttaga tgatgctttt ttagatttat
      361 actataaggt atataaaact aagtttatta aaaatgttat aatttctatt gctatcatag
      421 accatatcaa tccatcaagt tcataaaagt aattaagctt tattaaatag cttctttatt
      481 ataatttctt tatttcatat aatataaata gtattaaaat ttttatggga gttaaagtaa
      541 gcatgtatta ttacttagat atttgtataa tcaacatcta gtaatttacc tttttggtga
      601 aaatgattaa taagtttttt aggataattc attattaatt catctggaaa attaatttcc
      661 tttaagatat tttcagaata ctcatagtta cctatgtcaa aacaaatgtg agcatctgaa
      721 gtcagtatga ttttagcacc atattttttg caaagtgtag caatatactt acagttatcc
      781 gagctaccat ttcttgacac gcctttaata gaacaattat ttatttctat taagatattc
      841 ttttctatag ctaatttaat gattaattca tagtcgattg ggtagtttgg gtttccaagg
      901 tgtcctaata tttcaatatt atcatgctta tttattgcat ttattaaagc tttagtatta
      961 ttctctaatg tatttggaga aaacacagct tcgtgaaatg acaagataag ataatctaac
     1021 cgaggaatta caaaaggctc taggtctatg tttcctttaa tatctagtat atttgcttca
     1081 cagcctctta aaattataat gttatttatg attcttggga tattttgaat gttgtgaaag
     1141 taccatttgt ggggagaacc aggcatctta ggaccatgtt cagatgtacc tagtatctta
     1201 attccatttt ctttacaata attaatattt tctagtaaag tgctatagcc atgaccactg
     1261 actatagagt gtgtgtgtaa atctgataaa aaattcatat aaattcctcc tctataaaag
     1321 atgagggtaa cgtaatttat attataaaac gaataggaaa gaaaatcaat agttacataa
     1381 ttagacaaaa atattaaaat attgtagaat taagcttaat aataaatgtt taacagtatt
     1441 actgcttata ggggaggtta actatgacac aaaagaagct atcaaggaaa gaaaaagttt
     1501 taatttgctt gaaaaggtta acagaagaac acttgaactt taataatggc attagatttg
     1561 gatttgatgc agaatatata gctactgaag taggtataaa tagaagtaat gctagtaagg
     1621 aattaaatca attaataaaa gaaagtatta ttataaagat aaagggtaag cctgttcagt
     1681 acttatataa agaaagtatt gagagtattt taggaaagaa actaaataaa gggatatttg
     1741 ataatattaa ctctataaac gaatatagtg aaaatgattc tatcaaagat gagtatattt
     1801 tagagagtat aaaaaaagag aacaatattt ttaatttagt aggatgtgat ggaagtttaa
     1861 ggtcccaaat agaacaggct aaagcagcag taatatatcc acctaagggg ttgagtacat
     1921 taataatagg acctacagga gttggtaaat ctatatttgc agaatatatg tataagtata
     1981 gtttaactat aaaagaagat agtgataatg caccatttat catatttaac tgtgctgatt
     2041 attctgataa tcagcaatta ttattagcgc agctttttgg atatgtaaaa ggagcattta
     2101 ctggagctga taaagataag tatggtattg tacatgaagc taataatgga gtattgtttt
     2161 tagatgaagt tcatagatta tctgcagagg gacaagaaat gctatttctg cttatggata
     2221 aagggatata tagaaggtta ggagaggcta ataaggtaca cgagtgtaga gttatgataa
     2281 ttgcagccac tacagaagac ccagaaacag caatgttgga aacgttttta agaagaatac
     2341 ctgtaactat aaagattccg tctttagagg aaagaggctt tcaagagaga atgaagctta
     2401 tatgttattt ttttaaagaa gagagtgtta ggattggtgt taagttaaag gtttcaaaag
     2461 aagttattaa ggcatttatt ttatataagt gtaagggaaa tataggccaa ttaaaaagcg
     2521 atatacaatt aatttgtgca agagcttttt tagattatat gacctataaa agggaatgtg
     2581 tatatgtaag gctctctctt ctaccaaata atattagaga atcattatat ggaaataata
     2641 gaaaagagga gtttgtacaa aatttcagtt ttattggaaa agatgatatt atttttttac
     2701 cagaagaaaa ggattttgaa agtgaaaatt tattaataga aaataaaaaa tatgatttag
     2761 atttttatgg aatgataaaa gaaacttgga ataaacttca acaagaaggt attaaagagt
     2821 cacaaattag aagtgttata gatggagaca tacagaagta ttcctataat ttaatgaata
     2881 cttttatata taatagtagt aatcaaacag cttataacaa cattgttaat gattcaattg
     2941 caactactgt aaaatatatt ttacaaaagc atgataaatg gagcaaaaga gaaggattag
     3001 ataaattaat aaaagctata gctttacata ttcagaattt aattgaaaga ataaagattg
     3061 gaaatatagt aaagcatcct aataaagatg aaattatgaa ggaaagagca tatgaatata
     3121 acatagcaaa agaaatatta tctaacatgt cattaatgta tggagtagag tttccagaag
     3181 atgaagcaat ttttttagca acatttcttt atttatcgta tgtgggatta aatgaggaga
     3241 gtatagcaat attagtcata atgcatggtg aatctacagc atctagcatg gtgaatgtag
     3301 ccaatacttt actggattgt aaccatgcag tggcaattaa tatgggatta gaagatagag
     3361 ttcaggatat tttagtacaa gctgtagaaa tagccaataa aattgataaa ggaaaaggaa
     3421 ttttaatttt aactgatatg gggtctattt taacatttgc taaagttatt cgtgatgcta
     3481 caggaaaaga agtaaaagca atagatatgg taagtacacc tattgtaata gaagcaacta
     3541 gaaaggctct aactccagaa atgacattag agaaattata ttttaatatt atagaatcta
     3601 taaagaaaca ttatggagat atggaagtta catatgctga aaaagataat ggtggtagat
     3661 attttgatag attactaatt gataatatta gtaaaacttt gactttttta aatggggaaa
     3721 aggcttattt tatattaaaa gaagtaatta atagaattag tgaacactat tctttagtaa
     3781 ttcaagatga acttttagta aagtttatat ttcattgttc atgtatgatt gaaagagtaa
     3841 taataaaaga gtctttagtt tataaatcat atgaagaaag aattagtaga aataaagaat
     3901 tatatttagt tataaaagaa agttttaagc tagtagaaga gacattcgat ataattattt
     3961 cagatatgga atatgcaaat atattagata tatttgaatc acaatatgat acagataaat
     4021 tcaaaagttg atacaaaatt taaaaatagc caaaaggcta tctttttttt actttttttg
     4081 atacagattt gatacaggtt gaaaaaatct tttgatacat atcgaaataa taagttttta
     4141 aaaaaaattg agtaaaaagt tttgattaaa tcctgtaaaa tagccatttg ttattgatac
     4201 acataagttg gcacggcaat tgcttatata aaaagtgaca agaaaagtga ggtgaaattg
     4261 gtgataggaa taatagttat gactcatggg agttttagtg aagaaattat aaaaagctgt
     4321 gaacttattg caggaccagc agaaagaaca gcagcaatta aactaaatag gaatgataat
     4381 attgaagact taaataaaaa ttttgtagaa aagttaaatg aattagatga aggtgacgga
     4441 gttttagtat tagctgacct attaggaggt tcgccaagta atgttgcaag tttaaacctt
     4501 aaaaaaggtg gcaagtttca tgcacttact ggagtaaatc ttccaatgct acttgaagct
     4561 ttaattaata gagagggaaa aagtttagaa gagttagcag aagcatgtat tgaagcagga
     4621 caaactggta taaacaatat taataaagtt cttagctcaa tgtaatagaa aaaggagttt
     4681 gattaaaaat gtctttagta aaatattgca gatgtgatga tagattaata catggtcaag
     4741 ttatatataa atgggttaag catctaggtg taaaaaagat agtagtagta gatgatgaaa
     4801 caaccaatga tgttattgct aaaggtttga taaaaatggc agcaccaaag aatattgatt
     4861 tatcaatatt aactgtaagt gaatcaagga gatattttta taataatcaa gctgatgata
     4921 acgtttttgt attaattaaa aatttagata ctgcaaatag aatgatagaa gaagggatta
     4981 atatcaaaaa acttattgtt ggaagaatac ctacaggaat aggaaaaaag aaaatatctc
     5041 aaaatgtata cattaataaa aaagagtttc ttttaataga tgaatttatt aaaaagaata
     5101 ttaatgtatc aattcaaatg gtacctgatg aagaagaagt agaattaaac caaaatatta
     5161 atcgctataa aggagagttt atttagcaat gaataaatat aaggtaatca tactgtgcca
     5221 tggaacttgg ggaaaagtct tagtagaaga aacaaataaa aactttggat tgtcaaatca
     5281 atatgaagtt ttatcactaa gttctgaaaa agatgtttct gtatttatga aagaggttga
     5341 agaagtagta gataaagaag atgtgaaaat tataatatca gatttatatg gaggatctac
     5401 atcaagtgtt gcaatagctg ttgctataag aagaggaata gatgcaataa atggacttag
     5461 cttacagaca attttaatcg tagatgaaga attaagcaaa gaagataaat tacatacatt
     5521 accagaaaga atcgtcaaaa aaaataataa cctttgtgtg gatttaatta aagaatttaa
     5581 aaaaatataa attatgaggt gaatataatg gcaaaaataa cattagtaag agtagaccac
     5641 agattaattc atgggcaagt tataacaaaa tgggtaaaaa tcgctcaagc tcaaaaaata
     5701 ataatagttg atgacttctt aggtcaagat gaatttatgg ctgacatata taaaatggca
     5761 gcaccatcag gagtagaagt agttatttta acagcagaag atgcgggaca agcattccaa
     5821 aacaacactt taggagataa aaatatattt attctattta aaaatgttga tatggcaaat
     5881 aaggcttata aagctggact taaatatgaa aagattcaat taggaggtat tccaaatgaa
     5941 gcaggaaaga aaatggtgtt tacagctgtt tcattaggaa atgaggatgt agaacaactt
     6001 aatgaactta atgaaaatgg ggttgaaata gtcctacaag ttataccaga ggaatcatct
     6061 atgacatatg aaaatgcgtt aaagaaattt aaataaaaaa tataaattag gaggaattat
     6121 aaatggaatc tgttttgatg ttggcaattg taacaggatt atggtattgg tttgcagcag
     6181 gtcttgcagg gtataccctt ttctcaacac taaagtctcc tttatttata ggttttagcc
     6241 ttggattact ttggggtgat gtaacaactg gtatgattgt tggtgcaagt atagaaatgg
     6301 tttatctagg aatggtcgca gcagggggaa atattccatc agataaatgt ctagctgctc
     6361 ttattgcaat accagtagca cttcaaactg gtgttaatgc agaagttgca gtatctattg
     6421 cggtaccttt aggtgttata ggagtattag ttaataactt aagaagaact ggtaatgctg
     6481 tattggttca taaggcagat aagtatgctg aagaaggtaa tacaaaaggc atctggagat
     6541 gtgcaacact ttattcttta atatttgggt ttgttttaag gtttccaata gtttttgtat
     6601 gtaacttttt tggagcagat ttagttcaat cattattaga tgttatacca caatggttaa
     6661 tgaatggatt aacagtaatg ggcggtatat tacctgcatt aggttttgca acaacaatat
     6721 ttactatagg taaaaataaa tttttaccaa tgtttattat aggatttttt atggttcaat
     6781 attttgaaat atcaattact gcagctgcaa tatttggtgt ttgtatagct cttttaatta
     6841 cctttatgaa agaagacaaa agggtaggtg aagtataatg caagaaataa aaaataaaga
     6901 agttaaaaat ggacaaggtc caactgaagt taataagaca agagtactta caaagaaaga
     6961 tgtaacaaaa acatatctaa gatggtggtg gacagcagaa ttatccaact cttttgaaag
     7021 aatgcaagca ttagcagttt gtgcaagttt cactccggct ttagaaaagt tatataagag
     7081 aaaagaagat ttagtagatg cgttaaagag acacttacaa ttttttaata ctcaagctat
     7141 atggggagga ttaattcacg gtacagtttt agctatggaa gaagagaaag ctactgaagg
     7201 aaaaatccca ggagaagtta tttcaggtgt taagaatggt cttatgggac ctttggctgg
     7261 aattggagat actttagatt ttggtacatt tcaaacaata ttcttagctt taggtgcttc
     7321 atttggagca gaaggaagtg ttataggtgc atttttccca ataatgttta gtatattact
     7381 attttgcgaa ggttattact tatttcattt aggatattct ttaggtagag attcaattaa
     7441 gaaaattcta tcaggtggta ttgtcaataa gataattgat ggtgcttcaa ttctaggaat
     7501 gtttatgatg ggagcattat ctgcaactac agttaagctt tcaactccgc tatcatttga
     7561 tattggtggt aaagcaattg ttgttcaaga tacattaaat atgattgctc caggtttatt
     7621 accacttggt gttgtattct tcgtatattg gggaatgaaa tacaagaagt ggacaataac
     7681 taagttatta gtaattttag ttgtattagc attggtaggg tcattcattg gaatattcta
     7741 attcacagtg attaaaatat agaatttaat tttaggagga gaaagaaatg tcagaaaaaa
     7801 tgtatacaga aaaggaatat ttagaaggaa ttagaggagc aacaggagaa agagcagtat
     7861 ggttctatct tcttatgaaa gaagctgaaa aattaggagc taatccagat gatatatgta
     7921 aagaagcaat atatggattt ggtaaaatga gaggtcaaaa atataacgta gcagatactc
     7981 caggaaaaat ggcagaaatg ttatataaca gtaaaggaca aaaagtgttt gaaatggaat
     8041 tagtagaaaa tacagatgag aatggcgttt taaaattcca tcactgtcca ttagatgctg
     8101 cttggaaaga atatggatta actaaagaag aaagaaaaga aatttgtaga ttagcttgtt
     8161 atggggatta tggaagagtt gactgcgcac aaggtgttaa attagatttt gctcaaaaat
     8221 gtgctcatga tgatgaagtt tgtgaattag tatttacaaa aaaataattt ttaatgctaa
     8281 aagcctgttc tttaaggaca ggctttaaaa agatagaaag taggttgatt tatggatata
     8341 agcagaagtg tagataatag tttaaataga accatagaat ttctaaaaga attgataaaa
     8401 attgattcac aacaaggtga acctatttca caatgtcctt ttggtatagg acctaaaaaa
     8461 tctttagata aaactttaga ttactgtgct agtttaggtt ttagtgttaa aaatattgat
     8521 aattatattg gatatgcaga aattggagag ggagaggaat taatagggat tccaatgcat
     8581 ttagatatag ttccaccagg agaggggtgg agtgtagacc cattttcggg agcagtaatt
     8641 gacaatatta tttatggaag aggtgtcata gataataagg gtgctgtatc tatgcttata
     8701 catgtattga aaaacataga ggatatgtat cctacaatta ataaaagaat aagattaatt
     8761 tttggtacaa atgaggagac aggtatgaaa tgtatcaaat attacttaga taaaggtgaa
     8821 gaaattccaa gtatgggatt tactccagat gctatgtatc cagtggttaa tggagaaaaa
     8881 ggaagggttc atataaggat agaaaaagaa attaaaattg acaaaagtaa accttacata
     8941 atagtaaggg gaggaactaa agaaaatgtt gttccatctc attgtactgc aaaaattatt
     9001 aatggaatta tttcagagtt aactactaaa ggagtagctg tacatgcaag taatcctgaa
     9061 aagggagaaa atgctatatc taaaatggta ataaagatag ttgaggataa tatggatttt
     9121 cagcatagag aagatataga attagtttca aaataccttt gtagtgatta ttatggagat
     9181 gcattgggga ttaatcaata tgatgaggta ttcaaaaaca ctaccttaaa tttaggaata
     9241 ttaaaagtaa atgaggaaaa aatcgtatgt gagttagata taaggtatgg taaaaatata
     9301 gttttaaata acataataga tagattcaaa aaggtttttt gtaatggttg gaaaatagag
     9361 gttattgctc ataaagactt acattatgtg gatgagagta atttagtact taaaaaatta
     9421 ttagaagcct atgaagaagt aacagatgaa aatggatata caattgctat gggtggtggc
     9481 acatatgcaa gttggtttaa agatatggtg gcgtttggac ctaagttctt agcgtataaa
     9541 actggtggtc atggagtaga tgaaagagta ccaataaatc atatacgaaa gaatatggag
     9601 atatatactt tggctttaat aaaactatta gaattgtaaa agaagaagag actttatgtg
     9661 caaatttaca gatatcttaa aaagagagat aaaacgagtt caaccttatt taaatgttca
     9721 acaccatcaa atggggctgt ctcaaaatag agataagcct cttacttatt gttgaaatga
     9781 tgaaaatata ttttacttca tacaaaaaag agtgccttat gaagtaaaaa gttaattttg
     9841 agacaccctc atttgatgat gttgaagaga aaataagtat gaaattatta aaaaagatga
     9901 ttttaaaaaa gttaaggttg aaaagaaaag ttaattaaat ggaattagat aaatggagaa
     9961 ggatgtatac tatctaataa aataacaaaa gagtgttata aagttggtta tatgattaga
    10021 gaaaagtcta ttgatactta tccagatagt ggatggggat ttatgacttg ggatgaaaat
    10081 ggagaataat aaaaattata gtttatacag tttaataaga tatatgtaca agcagttaat
    10141 ctaaatgatt gactgctttt cttttataga tttttatata atagacaaat accaatacat
    10201 gatagttgcc tgttataatt agaggaataa atacgaataa taactttata aaagaattaa
    10261 atggaaaatc gaagagttat attcagtatt ttaaaaagaa tatgaaatga gaaatgaaaa
    10321 taaggtgttt atattaaaag aggttttaca caaaatattt aaaaacgtga taaataaaaa
    10381 ctgtatttag atagattaac tattagtttt atataatatg gattttattt acaaagttta
    10441 catattttac aaaagagatt aaagataaat ttaaatatat attttatata cttgtttatt
    10501 tgtttctctg tggttgattt tttcgtcaaa agtcaacttc aaatcgcttg ttagctttac
    10561 atgtttaagg atataattat acataaggag ggattgacat gaatgaatta aacatcgcaa
    10621 aaacgctgat tttaaagcgt aaagaaaaag gaattacaca agatgaactt gcaaattata
    10681 taggcgtttc taaagcttct gtatctaaat gggaaa
//
LOCUS       DAMJXI010000100        10686 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.106, whole genome shotgun sequence.
ACCESSION   DAMJXI010000100 DAMJXI010000000
VERSION     DAMJXI010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10686
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.106"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            210..989
                     /locus_tag="PC465_003416"
     CDS             210..989
                     /locus_tag="PC465_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HDF2650690.1"
                     /translation="MSYKKIAIITGANSGFGKEFLKLLINEEEITEIWAVARNKARLN
                     QLVDEFGSKVKIFSKDLSKIEEVKEIGTFLSKENVCIKYLINNAGFAKFCSYNDLSID
                     ESINMIDLNISAVVALGLICIPYMQKGSHIMNISSQASFQPLPYQNIYSSTKAFIRNY
                     TRALNVELKSKGINAIAVCPGWMSTNLFKRGIVVAEKGTKNFPGIVSPDIVAKKALKD
                     AKKNKDISVYGINTKSSHLLAKLLPQKMMMKVWLMQQHIKE"
     gene            complement(1299..2120)
                     /locus_tag="PC465_003417"
     CDS             complement(1299..2120)
                     /locus_tag="PC465_003417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002572585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallohydrolase"
                     /protein_id="HDF2650691.1"
                     /translation="MKLKIVGSGGMSIIPSSFCKCKICEEARQKGGRYERLGPSLYID
                     DIKMLIDTPEDIAVACNRQKISEVKHISISHHDPDHVKGIRIVEKIGCDFITGENNPI
                     GFYALPEVIEDINRTNLDCLKYYGDVINCISINETSHVKINNFDIDLINNNPDRNITF
                     YVIKENEKKVIYACCNPKPFTHSDMYFDTDVLIISLVSDDGILNDGTKLKDTPFKDEI
                     FTLDEIVEIKNYYRIKKIIITHIDEMWGKSYGYYSELEKKLDNIYFAYDGMEIIV"
     gene            complement(3130..3948)
                     /locus_tag="PC465_003418"
     CDS             complement(3130..3948)
                     /locus_tag="PC465_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2650692.1"
                     /translation="MFKIGDFSKLSKISIRMLRHYDEIGLLTPSHTNKTNGYRYYSAD
                     QLSTTNRIHALKDMGFGLYSIKEILTEYNDKESLIKYLNIHHSQVKEQLEDTQKKLLK
                     IETTIKRIGGNDIMKNYDVTIKNFAPKYMMTLRRVIPTYQDEGMLWHQVFLETKDQNV
                     QIEPPKYSKAVFYDTGYKEDYVDVEVQVAVSGKYKDTEHVKFKTVPSVTAATAIVNGN
                     FNQVADACEAIGNWISDNNYDVDGPMFNIYHVSPGNDSNPDNWVTEVCFPVKKK"
     gene            4116..4697
                     /locus_tag="PC465_003419"
     CDS             4116..4697
                     /locus_tag="PC465_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2650693.1"
                     /translation="MKSNDKDARERIIEVTLNLLNEVDDIEEITVRKIAERANVGVGL
                     INYHFKTKDNLLSTAIGDVMSNIIAELYDDSVYTLRPIEDLKNLLKKLCDTGLHYEKV
                     LPFVLNQCITNGDMQAELDIVPMLRKIFGNKKDEMSLRIIALQIILPIQISALSTESF
                     QLYSGINIKNKYERDKFIDILIENIIGEDVDVR"
     gene            4694..4888
                     /locus_tag="PC465_003420"
     CDS             4694..4888
                     /locus_tag="PC465_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650694.1"
                     /translation="MKIITIGSSLITVLLFLSTMVCGFWIKNNKVTDASSIKFHMNSA
                     IFTGIFLLISTILLIIYIKK"
     gene            complement(5052..6794)
                     /locus_tag="PC465_003421"
     CDS             complement(5052..6794)
                     /locus_tag="PC465_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M3"
                     /protein_id="HDF2650695.1"
                     /translation="MVKSKKKIFVFLILIAVFIIFASYIRNYTNDTKKDSVRGTIPFE
                     KMEYKRPNIQSICENINKCNDKLLTAKTAKEQLNLFNEVDKIYQDFYSTLTIAKIRNN
                     IDSSDEFYSKEYKYLMSKSVDVDMSYKDFQDRFVTSKFSKELEKELGKDTFNYLKNIG
                     KLNSKEVEGLLKKEQDLVVKYEDLLAKSTVSIDGIEVDFEEALSRPNLSPEEYVKIYS
                     DYLKKYNPIFGNIFLELIQTRTEIASKQGFKNYIDYAYMNLNKDYSQEEAKKFRQDVK
                     DYIVPLYREISSKPSDSSIYIKVYKNRSFRKFDKVLEDISPKLKESFDYMKKYDLYDY
                     SSGKNKSPGGYTTYINKYKAPFLFNTWDNSFLGVTSFAHEFGHFYNYYNSINLNNKIQ
                     PSIDVCEVHSTSLEILFYKYFDDFFGKQSEAIKKEHLSIVLNTIIDACLYDEFQEIIY
                     KNPYMSLNDINKLFFDLEEEYGVSNNILREKNAPFWILVSHNFQVPFYYLSYGLASDV
                     SLQIWQLSQEDYRKAVDVYMDFLNQNTDAGFKDVVEKVNLQLPFQNGNLEEISSTLYD
                     YFGIDNPLELKNAS"
     gene            7223..8599
                     /locus_tag="PC465_003422"
     CDS             7223..8599
                     /locus_tag="PC465_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HDF2650696.1"
                     /translation="MKTIVRRLILYADGMRPTQIMVSGFAAIIVIGALLLTLPIASQS
                     GESIGLLNALFTATSAVCVTGLVMVDTATYWSLFGQIVIITLIQIGGLGFMTVATMFS
                     LMARKKIQLRERLLIQESLNQADLSGLVRLTRFVLIITITIEGIGALVLSTVFIPQFG
                     LSKGIWYSVFHAISAFCNAGFDLMGSVSGPFTSLNSYVNNFTVSMTVCALIVLGGLGF
                     PVVLDIVRKRRFSKLNVHSKVVLFSTATLIFVGALFIFLIEFNQKATMADLPLKGKVL
                     SAIFQSVTARTAGFNTLDLATLRESSVFVMIILMFIGASPASTGGGIKTTTLAVLIIT
                     VRSFLSGKSDIEAFERRLAPSTIKKSLGIFVISISAVIFGTLIISITQPNFTLVQSAF
                     EVTSALATVGSSLAGTPNLNALGKIIIIIFMFMGRVGSLTLFMAILSGGRRKSQPIRY
                     AEGKIMVG"
     gene            8910..9581
                     /locus_tag="PC465_003423"
     CDS             8910..9581
                     /locus_tag="PC465_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HDF2650697.1"
                     /translation="MKQYIVIGCGRFGSSVASTMHLLGHQVMAIDKNEDSVQSISDKV
                     THSLIVDVTDEQALRSLGLGNFDVAVVAIGSDIRASIMATLIAKEMGVELIICKAKDE
                     LQAKVLYKIGADRVVFPERDMGVRVAHNLVSDNILDHIELDPEYSIVEIVTPNSWVGK
                     TLIELELRARYEITVLAIKTGKNINVTPSPDEELTAGSILVIIGQNTSITAITSGNKG
                     IIRRR"
     gene            9770..10567
                     /locus_tag="PC465_003424"
     CDS             9770..10567
                     /locus_tag="PC465_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HDF2650698.1"
                     /translation="MITNINSKDNEKLKYTRALLKSKNRNKESKFIIEGYRVVMLALE
                     CMANLDYVFINEEFENKKEHVKLLEDLDKKNTKIYKTTNKNFKELVDTENTQGIIGVV
                     SFKKKKLSESINKKDKFVLILDRIQDPGNMGTIIRTADSAGVDAIIALKGCVDIYNPK
                     VIRSTMGSIFDMNIIDASQDETVDMLKSLDFNIVSSYLNTENFYDKIDYGSKVALVIG
                     NEANGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKKYLI"
BASE COUNT         3972 a         1286 c         1603 g         3825 t
ORIGIN      
        1 tataatataa ttaacactac tttttaaata taatcaatac cgattctata atattaacac
       61 tattttttat gctatataac aattattgaa aatgatataa atataatatc tcaaataata
      121 tgaatataac atctgaatag agggtgtttt atttgtaaaa aataagttta cagtttgagc
      181 gtataaactt atggtaaagg agaataatta tgagttataa gaagattgca attataacgg
      241 gtgctaatag tggttttggt aaagagtttc taaagttatt aataaatgaa gaagaaataa
      301 cagaaatatg ggcagttgca agaaacaagg cgagattaaa tcaattagta gatgaatttg
      361 gaagtaaggt aaaaattttt tcaaaagatt tatcaaaaat agaagaagta aaagaaattg
      421 gtacattttt aagtaaagaa aatgtatgta taaaatacct tataaacaat gctggttttg
      481 caaaattctg ttcatacaat gatttaagta tagatgaatc tattaatatg attgatttaa
      541 atattagtgc tgttgtagca ttgggactta tatgtattcc atatatgcaa aagggaagcc
      601 atatcatgaa tatttcttca caagcatcat tccagccatt gccatatcaa aatatttata
      661 gttcaactaa agcgtttata agaaattata caagagcatt aaatgttgaa cttaagagta
      721 aagggataaa tgcaattgct gtatgtccag gttggatgag tacaaatcta tttaagagag
      781 gtatagttgt agctgaaaaa gggacaaaaa atttcccagg tatagtgtct ccagacattg
      841 ttgccaaaaa agcattgaag gatgcaaaga aaaataagga tatttctgtg tatggtataa
      901 atacaaaatc cagtcattta ttagcaaaac tattgccaca aaaaatgatg atgaaggttt
      961 ggttaatgca acaacatatt aaggaataag agtttcggta attaagtatc agttggagat
     1021 tcaatctgtt atatattatg agaagttttg ttgagcaaat aataattgtg acaaaacggc
     1081 ttatctagtg ccgataagcc gtctataatg tatataaaat atatttttga ttttacttta
     1141 tttagatatt gaagtattaa aatatgtagg acttgaaatt ttataaagat aaatactatg
     1201 atattttgta aaaactgaga tatgttgata ttacatagtt taactatact gttaaattga
     1261 agttttctta ttttgcatta tgcttattac ttaatgattt agactataat ttccatacca
     1321 tcatatgcaa aataaatgtt atcaagtttc ttttctaatt cactgtaata accatatgat
     1381 tttccccaca tttcgtcaat atgtgtaatg ataatctttt taattctata atagttttta
     1441 atttcaacaa tctcatctaa agtaaatatt tcatctttaa atggtgtgtc tttaagtttt
     1501 gtaccatcat ttaatatacc atcatcagaa actagactta ttattaaaac atcagtatca
     1561 aagtacatat cactatgagt aaatggcttg ggattacagc aggcatatat gacttttttt
     1621 tcattctctt tgataacata gaaggttata ttcctgtctg gattattgtt aatcaaatca
     1681 atatcaaaat tatttatctt tacatgtgaa gtttcattaa tagaaatgca atttataaca
     1741 tcaccataat atttaagaca atcgagattc gttcggttta tatcttcaat tacttcagga
     1801 agcgcataaa agccaattgg attattttct cctgtgataa agtcacatcc tattttttcg
     1861 acaattctaa tacccttaac atggtctggg tcatggtgag aaattgaaat atgttttact
     1921 tccgatattt tttgtctgtt acaagctact gcaatatctt caggtgtgtc tatcagcatt
     1981 tttatatcat caatatataa acttggccct aatcgttcat atcttccgcc tttttgtctg
     2041 gcttcttcac atattttgca tttgcaaaat gaacttggaa taattgacat accgccacta
     2101 ccaacaattt ttaatttcaa agttattaca ccaccttctt aaaatattag attatataaa
     2161 taatatacaa gcacaactga ttaacaaaat tatgagttaa taaattatat cacatgcaaa
     2221 tatgaaagaa tagtatgaaa tttttataaa catatattaa atgtttctca atgaaattga
     2281 ctttgtatat gaactgaatg acttattcaa tatggataag acatttttct tgtaataaga
     2341 tatgattgtc ctataaggtt tatgtaattt tgatataatt tgatataata tattgattaa
     2401 caacatacat gttattggtg agcatatttc tatagaatgg aatatataat tttttatatt
     2461 tatcattata tcattgtcta aagaaagtta aaaagagtag agcacaaagg aattatttgt
     2521 actttactct tttattgttt tgttaaaaaa actaatttat attagtgatt aaaatatatt
     2581 taactagagt ataaggatag tatataatct tataattgat ttatctgaca aattaagata
     2641 atatcctaat caaattctag tcatttaaac ataaaatcat aattgattta tctgacaaat
     2701 tgagataata tcctaattaa attgtaggta tttaaacata acattataaa taatttatct
     2761 gacaaattaa gataatatcc taatcaaatt ctagtcattt aaacacaaca tcacaagtga
     2821 tttatctgtc aaattaagat aatatcctaa ttaaattgta ggtatttaaa cataacatca
     2881 caagtgattt atctgtcaaa ttaagataat atcctaatta aattctagtc attcaaacat
     2941 aacatcacaa gtgatttatc tgacaaatta agataatatc ctaattaaat tgtagatatt
     3001 tatacataac actaaaagta atttgtttaa caaattaaga taatatccta atcaaattgt
     3061 aggtatttat acataacact aaaagtaatt tgtctaacaa attaaaatat tatccaatta
     3121 atataaaaat tacttctttt taactgggaa gcatacctct gttacccaat tatcaggatt
     3181 actatcgttg ccaggactta catgataaat attaaacata ggaccatcta catcatagtt
     3241 attatctgat atccaattac caatagcctc acaagcgtct gcaacttgat tgaaatttcc
     3301 attaacaatt gcagttgcag cagtcacact tggaacagtc ttaaatttaa catgttcagt
     3361 atctttatac tttccagata cagcaacttg tacttcaaca tctacataat cttctttata
     3421 tccagtatca taaaaaactg ctttagaata ctttgggggt tcaatttgaa cattctggtc
     3481 ttttgtctct aaaaatactt gatgccataa cattccttcg tcttgataag ttggtataac
     3541 ccttctaagt gtcatcatat attttggtgc aaaattcttt atagttacat cataattttt
     3601 cataatatca tttcctccaa ttcttttaat agtggtttct atttttaata gttttttctg
     3661 tgtatcttct aattgttctt ttacttgaga atggtggata tttagatatt ttatgagact
     3721 ttctttatcg ttatattctg tcaaaatttc ttttatagaa tacaagccaa agcccatatc
     3781 ttttagtgca tggattctgt ttgtagtaga aagttggtct gcactatagt atctatatcc
     3841 attagtttta ttcgtatgag aaggagttaa aagtcctatt tcatcataat gacgtaacat
     3901 acgaatacta attttactta gctttgaaaa atcgcctatc ttaaacatgt ttttgtctcc
     3961 tttataaagg tacttttagc ttaatattaa tataaaccat atcataatgt tagagtcaac
     4021 taaaattata attaaattat attgacatat gatgaaaaaa atattatact gaacatgttc
     4081 agaactgaaa atgttaattg ttttggaggt ctattatgaa aagtaatgat aaagatgcta
     4141 gagaacgtat aattgaagtt acattgaatc ttttaaatga agtagatgat attgaggaga
     4201 ttacagttag aaaaattgct gagcgtgcaa atgttggagt tggtttaata aattatcatt
     4261 ttaaaacaaa ggataatttg ttgagtactg ccataggaga tgtgatgtca aatataatag
     4321 cagagttata tgacgatagt gtatatactc taagacctat tgaagatttg aaaaatttat
     4381 taaaaaaatt gtgtgatact ggattacatt atgaaaaagt gcttcctttt gtgttgaatc
     4441 aatgtataac caatggagat atgcaagcag aacttgatat tgtccctatg cttcgtaaaa
     4501 tttttggaaa taaaaaagat gaaatgagtc taagaatcat tgccctgcaa attattttac
     4561 caatacagat ttctgcttta tctacagaat catttcagtt atacagtggt ataaatataa
     4621 agaataaata tgagcgagat aaattcattg atattttaat agaaaatatt attggagagg
     4681 atgttgatgt aagatgaaaa ttataactat tggttcaagt cttatcactg ttttactttt
     4741 tctttcaact atggtttgtg ggttctggat taagaataat aaggtaacag atgcaagttc
     4801 tattaagttc catatgaata gtgctatttt tacagggata tttttattga tttccacaat
     4861 ccttttaatt atatatataa aaaaataata atattattaa taaataaagt atcagaaatt
     4921 ataaagacaa gagtcttaaa aagttctgat actttaccat ataattttat taaacattaa
     4981 ttgtgtgtga aaaaatatca cttatttcaa tctaatacta aatcttaaga atgagtataa
     5041 agtattagaa attaagaagc attttttagt tcaagtggat tatctatacc aaaataatca
     5101 tataaagtag agcttatttc ctctaaattt ccattttgga aaggtaattg taaatttacc
     5161 ttttctacca catctttaaa tccagcatca gtattttgat ttaaaaaatc catatataca
     5221 tcaacagctt ttctgtaatc ttcttgtgat aattgccata tctgaagtga tacatcagat
     5281 gcaagaccat aactcaagta ataaaaagga acttggaagt tatgagatac aagtatccaa
     5341 aaaggagcat ttttttctct aagtatatta ttggaaactc catattcttc ctctaaatca
     5401 aaaaacaatt tattgatatc atttagactc atatatggat tcttgtatat aatttcttga
     5461 aattcatcat aaagacaagc atcaataata gtatttaaaa caatcgataa gtgttctttt
     5521 tttatagctt cagattgttt accaaaaaaa tcatcaaaat atttataaaa tagaatttct
     5581 aaagatgttg aatgaacttc acatacatct atacttggtt gtatcttatt atttaagtta
     5641 atactgttgt agtaattata aaaatgacca aactcatgag caaaactagt aacacctaaa
     5701 aaagaattgt cccatgtatt aaacaagaaa ggtgctttat atttatttat ataagtagta
     5761 tatcctccag gtgatttgtt ttttccagaa gaataatcgt acaagtcata ttttttcata
     5821 tagtcgaagc tctcttttag ttttggagat atatcttcaa gtactttatc aaacttccta
     5881 aatgagcgat ttttatatac tttaatataa atagaagaat cagatggttt agatgaaatc
     5941 tctctatata atggaactat gtaatctttt acgtcttgtc taaatttttt agcttcttct
     6001 tgagaatagt ctttgtttag gttcatatag gcataatcta tataattctt aaatccttgc
     6061 ttacttgcta tttcagttct tgtctgtata agttctaaga atatgttacc aaatatagga
     6121 ttgtattttt ttaagtaatc tgaataaatt ttcacatatt cttcagggct aagatttggt
     6181 cttgacaagg cttcttcaaa gtctacctct ataccatcta ttgatactgt agatttagct
     6241 aataagtctt catattttac aactaggtct tgctcttttt taagcaaacc ttcaacttct
     6301 ttagaattaa gttttccaat gttctttaga taattaaatg tatcctttcc aagttctttt
     6361 tctaattctt tagagaattt agaagttaca aatctatctt gaaagtcttt gtatgacatg
     6421 tcaacatcta ctgatttact cataagatac ttatattcct tagagtaaaa ttcgtctgat
     6481 gaatctatgt tatttctaat ttttgctata gtaagtgtac tgtaaaaatc ttgataaatt
     6541 ttatcaactt cattaaataa atttaattgt tccttagctg ttttagctgt taaaagtttg
     6601 tcgttgcact tgttaatgtt ttcgcaaatt gactgtatat taggacgctt atattccatt
     6661 ttttcaaaag gaatagttcc tctaacagaa tctttttttg tatcattagt ataatttctt
     6721 atgtatgatg caaatataat aaaaactgca attaaaatta gaaaaacaaa tattttcttc
     6781 ttggatttaa ccataaaaat cctccaatca tggatatagt tattaattat tttactatat
     6841 taaatataaa aaatgcatgt taagaaaatt taacataaag atatagataa gattataaat
     6901 aatataaaaa atttaacttc aaaaaagtat atgaaattta tactggtaaa atgataaata
     6961 aattttaagt acaaaatagt aaaagctatg atagttttag acctattata tgtaaaaaat
     7021 atagatgttt ttggtgcaat ttaaattaaa agatatatat aaaaatttaa aatattccaa
     7081 acagaaatta taaaaattac tatcattgtc tttatacaat atttatacta taatagaata
     7141 ataatttaga ggaaagctct aaaaataaac aaattaaggg tcttaacagt agtgatttta
     7201 tgttaaggag gtataaagaa agttgaaaac aatagttaga agacttattc tctacgcaga
     7261 tggaatgcgt cctactcaaa taatggtatc tgggtttgct gcgattattg taatcggagc
     7321 attgttgtta acactcccga tagcgtcgca gagtggagag agtataggct tattaaatgc
     7381 tctatttacg gctacttcag cggtttgtgt tactggtcta gttatggtag atacagcaac
     7441 ttattggagt ttatttggac agatagttat aataacattg atacaaattg gtggtcttgg
     7501 atttatgacc gtagccacaa tgttttcact tatggcacga aaaaaaatac aactaagaga
     7561 aagattatta atacaagagt cattaaatca agctgattta tcgggacttg taagacttac
     7621 aagatttgta ttaataataa ccataacaat agagggaata ggtgcactgg ttttatcaac
     7681 tgtctttatt ccacaatttg gtttgtctaa agggatatgg tatagtgtat ttcacgcaat
     7741 atcagcgttt tgtaatgccg gatttgactt gatgggcagt gtaagtggcc catttacatc
     7801 gttaaattct tatgtaaaca actttacagt atcaatgact gtttgcgcac ttatagtgct
     7861 tggagggcta ggattccctg ttgtacttga tattgtaaga aaaagaagat tttcaaaatt
     7921 aaatgtgcat tctaaggttg tattgttttc aactgctaca cttatttttg tgggtgcatt
     7981 atttattttt cttatagaat ttaatcaaaa agctactatg gcggacttgc ctttaaaggg
     8041 aaaagtacta tcagcaatat ttcaatcagt aacagcaaga actgctggtt ttaatacgct
     8101 tgatttagct actttacgag aaagtagtgt atttgtaatg ataattttga tgtttattgg
     8161 agcatcacct gcatcaactg gtgggggtat aaaaacaaca acactagctg ttttaatcat
     8221 tacagttaga agttttctat caggaaaatc agatatagaa gcttttgaaa gaagattagc
     8281 tccatcaact ataaaaaaat ctcttggtat atttgtaatc agtatatcag cagttatttt
     8341 tggaacattg attatttcaa taactcagcc taattttaca ttagttcaat cagcttttga
     8401 ggttacatca gcacttgcta cagttggttc aagtttagct ggaactccaa acttaaatgc
     8461 tttaggtaag attataataa taatctttat gtttatgggt agagttggtt ctcttacttt
     8521 atttatggct atactttctg gtggtagaag aaagagtcaa ccaatcagat atgcagaagg
     8581 taaaattatg gttggttaag ttaccaagaa gtagtataaa tttataatgg atttagagta
     8641 gcactgtaaa tctgttgata aaataaatga gcctagatgt aattatatga agaaataaaa
     8701 tcgactaatg aacaaaatta attaatgaaa taaaaaaaca gggaaataaa atacaaataa
     8761 aaaggtaaat caaaattaaa ttaatctgtg tatataaaat tatatattgt gtataagttt
     8821 tgtatgtgta aagtatataa gttttgtatg tgtaaacaat taatttaaga gatattatat
     8881 aaattgtgta ttagggagga agtttcgaga tgaagcaata tatagtcatt gggtgtggga
     8941 gatttggaag ttcagttgcg tctactatgc atcttttagg acatcaagta atggcaatag
     9001 acaaaaatga agattcagtt caaagtatat ctgacaaggt aacccattca cttatagtgg
     9061 atgttactga tgagcaagcg ttaaggtcat taggtttagg taactttgat gtagcagtag
     9121 ttgcaatagg ttctgatata agggcatcta taatggcgac tcttatagcc aaagaaatgg
     9181 gtgtagagtt gataatatgt aaggcaaagg atgaattaca agctaaagtt ctttataaaa
     9241 ttggtgcaga tagagttgta tttccagaaa gagatatggg agtaagagtt gcacacaatt
     9301 tagtttcgga taatatatta gaccatattg aacttgaccc agagtattca attgttgaaa
     9361 tcgtaactcc aaatagttgg gttggcaaga cacttataga gcttgaatta agagctagat
     9421 atgagataac tgtacttgct ataaaaacag gtaaaaatat aaatgttaca ccttctccag
     9481 atgaggaact tacagccgga agtatcctag ttataatcgg tcaaaatact agtataacag
     9541 cgataacatc tggaaataag gggataatta gaagaagata atttactatt taatatatat
     9601 ttaattgcaa tgaaagtaga tagtatcata taattatgaa tagttatatg atactatttt
     9661 tttaatcgaa ggtagtattt atttgtaaga ttagataaag agaaattaaa ttaaaagtaa
     9721 ggaggctgtg ctaatataaa aatttataag ttattagcat ttagataaaa tgattacaaa
     9781 tataaacagt aaggataatg aaaagttaaa gtatacaaga gcactattaa aatcaaagaa
     9841 taggaataaa gagtcaaagt tcataataga aggatacaga gtagtaatgc ttgcacttga
     9901 atgtatggca aaccttgatt atgtatttat caatgaagaa tttgaaaata agaaagaaca
     9961 tgtaaaacta ttagaagatt tggataaaaa aaacacaaag atatacaaga ctactaataa
    10021 aaactttaaa gaattagtgg atacagaaaa tactcaagga ataataggtg tagtttcatt
    10081 taagaaaaaa aaattaagtg aaagtataaa taaaaaagat aaatttgtat tgattttaga
    10141 cagaatacaa gacccaggaa atatggggac tataataagg actgctgatt ctgctggagt
    10201 agatgccata atagcactaa agggatgtgt cgatatatac aacccaaaag taattaggtc
    10261 tactatgggt tctatttttg atatgaatat aattgatgct tcacaagatg aaactgtgga
    10321 catgcttaaa tcattggatt ttaatatagt ttcaagttac ttaaatacag aaaattttta
    10381 tgacaaaata gattatggct caaaagtagc attggtgata ggaaacgaag caaatggaat
    10441 aaatgaagaa cttgtatcaa agtctgatat tttggttaag atacctatat atggtaaagc
    10501 cgagtcgtta aatgctgcga taagctctgc tatactgatg tatgaaataa aaaaatactt
    10561 aatttaatgt attgtaataa atataatgtc atgttataat cttgaattaa atagtagagt
    10621 atcaaaaata gtcaatatat attaaaaaaa taattaaatt aattatatat tagatgtata
    10681 ttatat
//
LOCUS       DAMJXI010000101        10504 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.107, whole genome shotgun sequence.
ACCESSION   DAMJXI010000101 DAMJXI010000000
VERSION     DAMJXI010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10504
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.107"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            34..432
                     /locus_tag="PC465_003425"
                     /pseudo
     CDS             34..432
                     /locus_tag="PC465_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434143.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            420..1358
                     /locus_tag="PC465_003426"
     CDS             420..1358
                     /locus_tag="PC465_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HDF2650699.1"
                     /translation="MENLILSINVVLPLFLTMSLGYVLKKLGLFDTHTLNKMNNVCFK
                     SFLPLLLFFNIYNTDLDGSLNFRLMAVAVIIIFSIFLILVFIIPKIEKDNKTRGALIQ
                     GVFRSNFVIFGIPVTISLFGDKSIGVTSLLIAVIVPMFNVLSVVILEIFRGGKVNIKH
                     MIKSVLTNPLIIASFIGLTMLILNINIPTFLHKTIGDISKIATPLSLIILGGSFSFSA
                     IKGHINPIILGVCGKLILVPAIFLPISIFLGFRNVELASLMIMLSAPTAVSSFTMAQQ
                     MDSDSELAGQIVVFTSGFSIITVFLIIFILKQNNLI"
     gene            complement(1742..1966)
                     /gene="secG"
                     /locus_tag="PC465_003427"
     CDS             complement(1742..1966)
                     /gene="secG"
                     /locus_tag="PC465_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HDF2650700.1"
                     /translation="MSNILMGVQVVLGILLVISIMPQDSKNALPSEFGGEGSQAYFKP
                     KGKQAFLARVTKITAVLFFINALALLIVKK"
     gene            complement(2571..3863)
                     /gene="eno"
                     /locus_tag="PC465_003428"
     CDS             complement(2571..3863)
                     /gene="eno"
                     /locus_tag="PC465_003428"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HDF2650701.1"
                     /translation="MSVIELVYAREVLDSRGNPTVEVEVVLEDGAMGRAIVPSGASTG
                     AFEAVELRDGDKGRYLGKGVETAVANVNEIIAPEIEGMDAFDQPAIDAIMIELDGTPN
                     KGKLGANAILGVSMAVARAAADEIGLPLFQYLGGVNAKQLPVPMMNILNGGEHADNNV
                     DVQEFMILPVGACCFKEGLRMGAEVFHSLKKVLGEKGLACGVGDEGGFAPNLGSNREA
                     LELIVEAITKAGYKPGEDVMLGLDVAATEMYNKETKKYVLAGEGKELTAAEMVALYED
                     WSNNFPIITIEDGLDEEDWDGWKLLTEKLGNKLQLVGDDLFVTNTERLEKGIENGVAN
                     SILVKVNQIGTITETLDAIEMAKRAGYTAVISHRSGETEDSTIADLAVAVNAGQIKTG
                     APSRTDRVAKYNQLLRIEEMVGEQARYCGLKSFYNLKK"
     gene            complement(4451..5983)
                     /locus_tag="PC465_003429"
     CDS             complement(4451..5983)
                     /locus_tag="PC465_003429"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003228330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HDF2650702.1"
                     /translation="MMKKPVALIIMDGFGYNKDVKGNAIAESKTPNLDRIKKEYPNTL
                     INASGLDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKSIKDGDFFTNKVLCEAMD
                     NAKENSLHVMGLLSDGGVHSHIDHLKAIIKMAKDKGVQKVYVHAFTDGRDTDPQSALE
                     YAKEVQVSMDEIGVGEFATVSGRYYAMDRDKRWERVELAYNAMVRGIGEKANSIEEAI
                     QNSYDDGKNDEFIMPTVIMKDDKPVGSIKENDSIIFFNFRPDRARQITRALVCEEFDG
                     FKREDIKNFFVCLTEYDITIENVHIAFGPQSLANTLGEYLAKNGKTQLRAAETEKYAH
                     VTFFFNGGVEEPNKGEERLLIPSPKVATYDLKPEMSAYELTDKALDKLGEDKFDFIVL
                     NFANPDMVGHTGSIEAAIKAVETVDTCVGKLIDKIVELGGSAIITADHGNAEYMLDPE
                     TGKTVTAHSINPVPFIVVGQEYESAKLLDGGRLSDIAPTVLDMMKLEKPEEMTGHSLI
                     SK"
     gene            complement(5992..6735)
                     /locus_tag="PC465_003430"
     CDS             complement(5992..6735)
                     /locus_tag="PC465_003430"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HDF2650703.1"
                     /translation="MRKPIIAGNWKMHKTIKEALEFVNEVKDKVNSDKVEAVICAPFT
                     LLKDLKEATKGTNIKIGAQNMHFEEKGAFTGEVSPLMLKEIDMDYVVIGHSERRQYFN
                     ETDETVNKKVLKALEVGIDPILCVGETLEQREAGKTKDVCKVQVEKALENVLKDDLAK
                     VVVAYEPIWAIGTGKTATAEDANDVISYIREVIKGLYGELANEVRIQYGGSVKPSNVA
                     EIMGQSDIDGALVGGASLASNDYLDLVNF"
     gene            complement(6761..7963)
                     /locus_tag="PC465_003431"
     CDS             complement(6761..7963)
                     /locus_tag="PC465_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HDF2650704.1"
                     /translation="MSMLNKKTIEDIDVCGKKVLVRCDFNVPLQDGVITDENRLNGAL
                     PTIQYLISKGAKVILCSHLGKPKGEAKPELSLAPVAKRLSEMLGKEVVFAADDNVVGE
                     NAKKATEKMENGDVVLLENTRYRKEETKNEENFSKELASLAEIFVNDAFGTAHRAHCS
                     TVGAGEFLQERVCGYLIQKELKFLGEAVANPVRPFTAILGGAKVSDKLAVINELLEKV
                     DNLIIGGGMAYTFLKAQGYEVGTSLLEIDKVEYAKEMMEKAKNKGVNLLLPVDVVMAD
                     HFAPDATPIVTEDANVKEDYMGLDMGPKTIANFVKTIKESKTVVWNGPMGVFEFENFA
                     NGTLSVARAMAELTDATTVIGGGDSAAAVNQLGFGDKMTHVSTGGGASLEFLEGKELP
                     GIAALDNK"
     gene            complement(8185..9192)
                     /gene="gap"
                     /locus_tag="PC465_003432"
     CDS             complement(8185..9192)
                     /gene="gap"
                     /locus_tag="PC465_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDF2650705.1"
                     /translation="MVKVAINGFGRIGRLALRKMMEQQDKFEVVAINDLTDAKMLAHL
                     FKYDTAQGRFNGEIEVKEGAFVVNGKEIKVTAERNPADLPWAELGVDIVLECTGFFTS
                     KDKAEAHIQAGAKKVVISAPATGDLKTIVFNTNSDILDGSETVISGASCTTNCLAPMA
                     KVLNDKYGIEKGLMTTIHAYTNDQNTLDGPHPKGDLRRARAAAGNIVPNTTGAAKAIG
                     LVIPSLKGKLDGAAQRVPVVTGSITELVCTLGKNVTVEEINAAMKEASNESFGYTEEM
                     LVSSDIIGISYGSLFDATQTKVMEVDGKQLVKVVSWYDNEMSYTSQLIRTLGYFAQLA
                     K"
     gene            complement(9252..10274)
                     /locus_tag="PC465_003433"
     CDS             complement(9252..10274)
                     /locus_tag="PC465_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2650706.1"
                     /translation="MKNLLEIQKKLIPQAIELMERRYSILRQISLSEPIGRRTLSNVL
                     EISERIIRSETEFLKEQGLIDVAVSGMTITKEGSDLLDKLKDIMSDIMGLSKLQDRVR
                     EKLGIKRVILVPGSCDENGSLLKDVTRYGCEYFLGILKDGDIVSITGGSTMLEFSNVI
                     KTDKRYPNSTIVPARGSMGTDVEMQSNNIVASISKKLHSNCKLLHIPDELDESAMKTL
                     SQVPEIKTTLEYIKRTDILVFSIGRADVMAKRRKLPEDKVDEILSKNAVGEAFGYYFN
                     KDGEIVYKLNTVGIDLETVKQVKETIAIFAGTEKVEALLAISNMHKNMVLVTDEESAY
                     KILSLL"
BASE COUNT         3240 a         1922 c         1194 g         4148 t
ORIGIN      
        1 taactaattt atataaaatc ttaaggagtt gccatgataa aaaaaataga gcatgtggtc
       61 attactaata ataatataga aaattatatc aatttttata aaaaatttgg tttttcatct
      121 aaagaaatga gcaaaaatta taaacttaat gctagaaatg ttaagataaa tcttaacata
      181 aaaggttata aatttttacc ttatgttaaa aattcaaaag caagtagaga taacttatgt
      241 tttaaaataa acacaaatat tgatgagcca aaaaaatact tagaacaaaa tgagattcaa
      301 attaagtgag gaattgtaga atgtacaggt gtctttggta atatgaaatc tatttatttg
      361 aaaaaaacta atggaaattt aattgaatta tcaaatcata gaatcacgga gagtaaacct
      421 tggaaaattt aatcctatca ataaatgttg ttcttccttt gtttctcaca atgtcacttg
      481 gatatgttct aaaaaaatta ggtctatttg atactcatac tttaaataaa atgaataatg
      541 tctgcttcaa gtctttcttg ccattattat tattttttaa tatatacaat acagatttag
      601 atggttctct taattttagg cttatggctg tagctgttat aattattttt tcaatcttct
      661 taatcttagt ctttattatt cctaaaattg aaaaagataa taagacaagg ggtgcattaa
      721 tacaaggtgt atttcgtagc aatttcgtta tatttggtat tcctgtgaca atttcactat
      781 ttggcgataa gagtattgga gtcacatctt tattaattgc agttattgta cctatgttta
      841 atgtattatc tgttgtaatt cttgaaattt ttagaggtgg caaagtaaat ataaaacata
      901 tgattaaaag cgtcttaaca aatccactca taatcgcctc ttttatagga ttgacaatgc
      961 taattttaaa tattaatata cctacatttt tacacaaaac tattggtgat atttctaaaa
     1021 tagctactcc tttatcactt ataattctag gtggctcttt tagtttttct gctataaagg
     1081 ggcatataaa ccccattata ttgggcgtat gtggaaaact tatacttgta cctgctatat
     1141 ttttaccaat tagcattttt cttggattta gaaatgtaga attagcttca cttatgataa
     1201 tgttatctgc tccaactgca gtttcttcat ttacaatggc acaacagatg gattctgaca
     1261 gtgaattagc tggacaaatt gtagtattta cttctggatt ttctataatt acagtatttt
     1321 taataatatt tattttaaag cagaataatc ttatttaatg atatttgata acacaaattg
     1381 gtattatgag aaacatatat aaaatcgatt taattgcgta aaaacatatt attatactat
     1441 ttttactata taatataact ttgtgtatat tatctcatta aacatggtga aagtagtgtt
     1501 gctatatatt ttttagtttg aaaaaaatat ataaatacaa acaatatata aatacaaata
     1561 ataaacgcca acaaatagtc aatctataaa ataaaaactg gactaatcat ataaaatcat
     1621 tagtccagct tttattttac gtacttttta tgttgatgta cttttattaa aaactaaatt
     1681 taatttttaa atgtctagca aatgcactaa ttaaataatg gccagttatt caacaatatc
     1741 actacttctt aactataagt aatgccaatg catttataaa aaataatact gctgttatct
     1801 ttgtaactct agcaagaaat gcttgttttc cttttggttt aaagtaagct tgacttcctt
     1861 ctccaccaaa ttctgaaggt aaagcattct tagaatcttg aggcattatg ctaattacta
     1921 gtaaaatccc tagtactact tgcacaccca ttaaaatgtt gctcattctt gcccctccta
     1981 tctgtttatt acttaaattt cattactctt tagtgtatca caataatata gccatttcaa
     2041 gactattatg ctataaataa catacaaaaa aatatattgt tactataata tattactata
     2101 ttctcaatat aaaaatgaat aaaacttaga agagaaaact atttaaatta atacataaat
     2161 taatgcataa attaacactt aaaataatct actctcattg catatattat aaatagccac
     2221 caaaataaaa caatcatttt aaaatattga tataactttt aatttcaaca taatttaaaa
     2281 taaataatcc acatttagca ataatacttt aatgacaatt atgattaaat caaaatatgt
     2341 cttcactttt attttttaat aaaaacctcc tatgcaatta gataaaaatg agatagaaac
     2401 atttattcat attttttctg aatctatgaa taaaattaag taataaaata taaaaaagga
     2461 taagtgaatt gaaaaatcaa ttaacactta tctcttttat atcttataag atgagcttaa
     2521 atatcttata ttctctcttc attaatcttt tttagtaacc attttaataa ctattttttt
     2581 aagttataga aagattttaa tccacaatat ctagcttgct ctccaaccat ttcttctatt
     2641 cttaataatt ggttgtactt agcaactcta tcagttcttg atggagcacc agtttttatt
     2701 tgaccagcat ttactgcaac agctaaatct gctatagtag aatcttcagt ttctcctgat
     2761 ctgtgagata taacagcagt atatcctgct ctcttagcca tttctatagc atctaaagtt
     2821 tcagttattg tacctatttg attaacttta actaatatag agttagctac tccattttca
     2881 attccttttt ctaatctctc tgtgttagta acaaataagt cgtcaccaac taattgtaat
     2941 ttatttccta atttttcagt taataatttc catccatccc aatcttcttc gtctaaacca
     3001 tcttctatag ttattattgg gaagttgttt gaccaatctt catataaagc aaccatttca
     3061 gcagccgtta actcttttcc ttctcctgct aaaacgtatt ttttagtttc tttgttgtac
     3121 atttctgtag cagcaacgtc aagacctaac ataacgtctt cacctggctt atatccagct
     3181 tttgttatag cttcaactat taattctaaa gcttctctgt ttgaacctaa gtttggagca
     3241 aatccacctt cgtcacctac accacaagct aatccttttt ctcctaaaac tttctttaat
     3301 gaatggaata cttctgctcc cattcttaaa ccttctttga aacaacaagc tcctactggt
     3361 aatatcataa attcttgaac atcaacgttg ttatcagcat gctctccacc gtttaatatg
     3421 ttcatcattg gaacaggtaa ttgtttagca tttactccac ctaagtattg gaataatggt
     3481 aaacctattt catcagcagc tgctctagct actgccattg aaacacctaa tatagcatta
     3541 gctcctaatt tacctttgtt tggagttcca tctaattcta tcatgattgc atctatagct
     3601 ggttggtcaa atgcatccat tccttctatt tcaggtgcta ttatttcatt tacgttagca
     3661 acagctgttt ctacaccttt tcctaagtat cttcccttat ctccatctct taattcaaca
     3721 gcttcaaaag ctcctgtaga tgctcctgat ggaactattg ctcttcccat tgctccatct
     3781 tctaatacta cttcaacttc tacagttgga tttcctcttg agtctaatac ttctctagca
     3841 tatactaatt caataactga catttgtata tctcccttcg attttctatt agttaaattt
     3901 tcatttactg taaacatccg tctactattt taatctactt tctatattat agtacataaa
     3961 gttgcttttg aaaattaggt acaaatttat ttgatgggta aatttgtaaa agttcctatt
     4021 tttattttat tttttataat attttaattt atataatata aaaaaacttg tctaaaatcc
     4081 aaaaccaatc ttaaatacac aaatattata actagattta aaacattaaa cataaaatgt
     4141 acaactaatg attctaaaat ttttgcttat ataatatata ttaattatta ttatttatat
     4201 tgttattgtc tatcttgtta ttatttatat cattatttac attattatct atattgtaat
     4261 tttttatttt ataaattgtc tatcttgtaa attttataaa acatatcttc atctacacct
     4321 tacaatatcc agaacttaca aaatttaaat cttatgtcat aaagtctaaa ctttacaaaa
     4381 taaacctaaa ctgcattatt tttaaattta tattgtagtt tatatattat tctctactta
     4441 tcaaaatcga ctattttgaa ataagtgaat gaccagtcat ttcttctggc ttttctaact
     4501 tcatcatatc taaaacagtc ggtgctatat cagataatct tcctccatcc aataattttg
     4561 cactttcata ttcttgacca actacaataa atggtactgg attaatagag tgagccgtta
     4621 cagtttttcc tgtttctggg tctaacatat attcagcatt tccgtggtca gcagttatta
     4681 ttgcacttcc acctaactct actattttat ctatcaattt tcctacacaa gtatctacag
     4741 tttcaacagc ctttatagcc gcttctatac ttcctgtatg acctaccata tcaggatttg
     4801 caaagtttaa tactataaag tcaaacttat cttctcctag tttatctaaa gctttatctg
     4861 tcaattcata tgctgacatt tctggtttta aatcataagt tgcaaccttt ggagaaggta
     4921 tcaatagtct ttcttcacct ttatttggct cttctactcc accattgaag aagaaagtta
     4981 catgtgcata cttttcagtt tcagcagctc taagttgagt ttttccattt ttagctagat
     5041 actcacctag agtgttggct aaagattgag gtccaaatgc tatatgcaca ttctctatag
     5101 ttatatcgta ctctgttaag catacaaaga agtttttaat atcttctctt ttaaatccat
     5161 caaactcttc acaaactaaa gctctagtta tttgtctagc tctatctggt ctaaagttga
     5221 agaatataat tgaatcattt tcctttatac ttccaactgg tttatcatct ttcataataa
     5281 ctgttggcat tataaactca tcattttttc catcatcata agagttttga atagcttcct
     5341 caatagaatt tgctttttca ccaatacctc taaccatggc attgtatgca agttctactc
     5401 tttcccatct cttatctcta tccatagcgt agtatctacc agaaactgta gcaaattcac
     5461 ctactccaat ttcatccata ctaacttgta cttctttggc atattctaat gcactttgag
     5521 ggtcagtatc tctaccatca gtaaatgcgt gaacatacac cttttgtacg cctttatctt
     5581 ttgccatttt gattatagcc ttaagatggt ctatatgtga atgtactcct ccatcagaca
     5641 aaagtcccat tacatgaaga gagttttctt ttgcattatc cattgcttca cataaaactt
     5701 tattagtaaa aaagtcacca tcttttatag attttgttat tctagttaaa tcttgatata
     5761 ctattctacc tgcacctatg ttagtgtgtc caacttctga atttcccatt tgaccatcag
     5821 gtagaccaac atcaagacca ctagcattta tcaatgtgtt tggatactct ttttttattc
     5881 tatctaaatt aggagttttg gactcagcaa ttgcatttcc cttaacatcc ttattgtatc
     5941 caaacccgtc cataataatt aaagcaactg gttttttcat catttcactc cttagaaatt
     6001 aacaaggtct aggtaatcat tactagctaa actagctcca cctactaaag ctccatctat
     6061 atcactttga cccattattt cggctacatt tgaaggttta acacttccac cgtattgtat
     6121 tctaacttca ttagctaatt ctccatataa tccttttata acttctctta tataagatat
     6181 aacgtcatta gcatcttcag cagttgcagt tttaccagtt ccaatagccc agattggctc
     6241 atatgcaaca actacttttg ctaaatcatc tttaagaaca ttttctaaag ctttttcaac
     6301 ttgaacttta caaacatctt tagtttttcc agcttctctt tgttctaaag tttctccaac
     6361 acataatatt gggtctattc ctacttctaa tgcttttaaa actttcttgt ttacagtttc
     6421 atcagtttca ttgaagtatt gtcttctttc tgaatgtcct attacaacat agtccatatc
     6481 tatttctttt aacataagag gtgaaacttc tcctgtaaat gctccttttt cttcaaagtg
     6541 catattttga gcacctatct ttatatttgt acccttagta gcttctttta aatcctttaa
     6601 taaagtaaat ggtgcacata taacagcttc tactttatca gaatttactt tatctttaac
     6661 ttcatttaca aattctaaag cttcttttat tgttttatgc attttccagt ttcctgcaat
     6721 tataggtttt ctcattttac aatctcctct atatattagt ttatttatta tctaatgctg
     6781 caatacctgg taattcttta ccttctaaaa attctaatga tgctcctcca cctgttgata
     6841 cgtgagtcat cttgtcacca aatcctaatt gattaactgc tgctgcacta tctccaccgc
     6901 caattacagt agttgcatca gtcaactctg ccatagctct agctactgat aatgtaccat
     6961 ttgcaaagtt ttcaaattca aatactccca ttggcccatt ccatactaca gtttttgatt
     7021 cttttatagt ttttacaaag tttgctatag tcttaggtcc catatctagt cccatgtaat
     7081 cttcttttac attagcatct tctgttacta ttggagtagc atctggtgca aagtggtctg
     7141 ccataacaac gtctactggt aataataagt taacaccctt attcttagct ttttccatca
     7201 tttctttagc atattcaact ttatctattt caagtaaaga agttcctact tcataaccct
     7261 gagcttttaa gaatgtataa gccattcctc cacctattat tagattatca actttttcta
     7321 ataattcgtt tataacagct aatttatcag aaactttagc tcctccaagt atagctgtaa
     7381 atggtcttac agggtttgca acagcttctc ctaagaattt taattctttt tgaattaagt
     7441 atccacaaac tctctcttgt aaaaactcgc ctgcaccaac tgttgagcaa tgtgctctat
     7501 gagcagttcc aaatgcatca tttacaaata tttcagcaag tgatgctagt tctttagaga
     7561 aattctcttc gtttttagtt tcttcttttc tatatctagt attttctaat aatactacat
     7621 ctccgttttc cattttttca gttgctttct ttgcattttc tcctacaaca ttatcgtctg
     7681 ctgcaaatac aacttctttt cctaacatct cagataatct ctttgctact ggtgctaaag
     7741 ataattctgg tttagcttct ccttttggct ttcctaagtg agagcataat ataacttttg
     7801 cccctttaga aattaaatat tgaatagttg gtaaagctcc gttcaatcta ttttcatcag
     7861 taattacacc atcttgtaat ggcacattaa agtcacatct tactaatact ttttttccgc
     7921 acacatcaat atcttctata gtttttttgt taagcattga cataaatatc tctcctttta
     7981 ataaagtaat tttttattgc caagtataat atagtacata cttttaccct attaaatata
     8041 tcatattatc atatttttat atatagtatg taacattatt taggtgtatt ttatatattt
     8101 tttcttaaaa aaagtcctga gtccgtagta ttaaactaca aactcggact ttgtcaatct
     8161 acttttctat tttctcaaaa ctgactattt tgctaattgt gcaaagtatc ctaaagttct
     8221 tattaattga gaagtataag acatttcatt atcataccaa gaaacaactt taactaattg
     8281 ttttccatct acttccataa cttttgtttg agtagcgtca aataatgaac cgtagcttat
     8341 tccgattatg tcagaagata ctaacatttc ttcagtatat ccgaaagatt cgtttgaagc
     8401 ttctttcata gctgcattta tttcttcaac tgtaacattt tttcctaatg tacaaactaa
     8461 ttcagttatt gaaccagtta caactggtac tctttgtgct gccccatcta attttccttt
     8521 taatgaaggt attactaagc ctattgcttt tgcagctcct gtagtgtttg gaactatgtt
     8581 tccagcagca gctctagctc ttcttaaatc accttttgga tgaggaccat ctaaagtatt
     8641 ttggtcatta gtgtatgcat gtatagtagt cattaatcct ttttctatac cgtatttatc
     8701 atttaatact ttagccattg gagctaaaca gttagtagta caagaagctc ctgatataac
     8761 tgtttcagaa ccatctaata tgtcactgtt tgtgttgaat actattgttt ttaaatctcc
     8821 agtagctggt gcagatataa caactttctt agcccctgct tgtatatgag cttcagcttt
     8881 atctttagat gtaaagaatc ctgtacattc taatactata tctactccta attcagccca
     8941 tggtaggtca gcaggatttc tttctgctgt tacttttatt tcttttccgt ttactacaaa
     9001 agcaccttct ttaacttcta tttctccgtt aaatcttcct tgagctgtat catatttaaa
     9061 taaatgagct aacattttag cgtctgttaa gtcgtttatt gcaacaactt cgaacttatc
     9121 ttgttgctcc atcatttttc ttaatgctaa tcttcctatt cttccaaatc catttatagc
     9181 tactttaacc attttcgcta cctcctataa agtaaatgta tgttttctag ctctgtgcta
     9241 ggtcttgact tttataataa tgacaatatc ttataagcac tttcttcatc tgttacaaga
     9301 accatgtttt tatgcatatt tgatatagct aataaggctt ctactttttc agtccctgca
     9361 aagattgcaa tagtttcttt tacttgttta actgtttcta aatcaattcc aacagtgttc
     9421 agtttgtaaa ctatttctcc atctttgttg aaataatatc caaatgcttc tccaactgca
     9481 tttttagata atatctcatc aaccttgtct tctggaagtt ttcttctctt tgccatgaca
     9541 tctgctctac ctatactaaa aactaaaatg tctgttcttt taatatactc caaagttgtc
     9601 ttaatctctg gcacttggct aagagttttc attgcacttt catccaactc atctggtata
     9661 tgtaaaagtt tgcaattaga atgtaatttc ttacttattg aagcaactat attgttagat
     9721 tgcatctcta catcagttcc catacttcct ctagctggaa ctattgtaga gtttggatat
     9781 ctcttatcag ttttaataac gtttgaaaac tccaacatag tgcttcctcc tgttattgaa
     9841 acgatatctc catcttttaa aatgcctaag aaatattcgc atccatatct agttacatct
     9901 tttagtaaac ttccattttc atcacagctt ccaggaacta atattaccct ttttattcca
     9961 agcttttctc tgactctatc ttgtaactta gacaatccca tgatgtcact catgatgtcc
    10021 ttaagtttat ctaacaaatc agaaccttct ttagtgatag tcatcccaga tacagctacg
    10081 tctataagtc cttgttcttt taaaaactca gtttctgacc tgattattct ttcactaatc
    10141 tctaatacat ttgataatgt tctcctacct attggttcac ttaaagatat ttgtcttaaa
    10201 atagagtatc ttctttccat aagttcaatt gcctgtggaa tcaatttctt ttgaatttct
    10261 aataagttct tcataacata ctccttattg ctttcctttc gggacttttt ttgtccctag
    10321 tgtttattta agtcccacaa gatattttta ttttatagga tttgcgtata gatttcaata
    10381 gtttttcaaa aactttttta tttttttatt ttataaaata tttctccacc attttcaaat
    10441 cacagtattt tttcttttta tataaggctt tttatatata tttttttata ttttcattct
    10501 aata
//
LOCUS       DAMJXI010000102        10165 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.108, whole genome shotgun sequence.
ACCESSION   DAMJXI010000102 DAMJXI010000000
VERSION     DAMJXI010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10165)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10165)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10165
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.108"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(176..2056)
                     /locus_tag="PC465_003434"
     CDS             complement(176..2056)
                     /locus_tag="PC465_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp10"
                     /protein_id="HDF2650707.1"
                     /translation="MSKRKSFIRTIAVSTMAVAVTGSATCAYAAPVLQGTKTYEKVNT
                     IDISVDSVENIVYSFQASIKVQGEVEVVDNEQKEKITWSDNIKSQIKSGNANATCRAE
                     YNKSSNTTTLDIYVTSNEDLLDGNRLNIGRISIKKSGSNSNADYKVLGKGTSDKPALK
                     IVTYNNKTLDYENISSDEGLIFTLINESEVKPIGGTGSSKNDPEKYKVEKSEALEYLL
                     NNIRINYSIVSKETQESGSNVILKLGLAQKTTKGRKATINKYVEVTLPKSLEYIVENE
                     LSKPDELPPDNGNGGNNGGGSNSGGSSSGGSSGGGNSSDSTSNVTVKKLKGADRFETA
                     IKISQSGWTKSDTVVIVNGEDKSMVDGLTATPLASVKNSPILLSSNEKLPQKTVEELK
                     RLNPSKVIVIGGNNSMPNSVVEAIKAVNSKISVQRIGGDTRYQTSINIAKEIDKTNNV
                     SKLYIGAGNGEADSLSIASLAGKEKTPIVLTQKDGVDNEAEQFIKSNKVSNIYFIGGV
                     EKISNKAIEQVGKIANKDISNNRVAGQTRQETNAKVIDKFYSQSKLDGVVVANQDKLI
                     DALAVGPLAAKNNSPVILATNTLDKSQESSLKGKNSSKLFEVGGGIASSVIDKIKSLI
                     EK"
     gene            complement(2266..8229)
                     /locus_tag="PC465_003435"
     CDS             complement(2266..8229)
                     /locus_tag="PC465_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-binding adhesion protein"
                     /protein_id="HDF2650708.1"
                     /translation="MKKAISCVLAVSMCSAPLNVFAEPILEGKLRAVEKSVTEKLRGS
                     LEVDLNFSLPIKNSESESMTNMQLRLKDDSNNSGIIKLGEKDSGTVNVGTDNIEYTIK
                     KLSASRSEIKNKDENISYYNIVFNNLPVGKYNVEVSGAGFKNKEIKDIDISSYSQRVL
                     LSNRASVDNKNKPLNYELFLMGDVNGDGKVDKSDYNKVLENIDSNKREFDLNRDGKVD
                     IVDLDYVQKNLGQSEDAKSLESIVSTNPIVDTSKVELKGNSDVDINGNVENLFSGENN
                     GVTISSKNDEISEEKPAVMDIALSEALNMEVINIKAPEGTAPAKGIVEVTDKDGNIQQ
                     IPYENKEYMKNLKDEEQQEEVNNEQEEVNQEEVNNKDENINQTDNNSNNKDENNDKQQ
                     ENSDKQEANSNTNQDKNNDKENSSMDKPNSDEDTPKEGDNISKDDNFTTSTYSRSALE
                     TYADVQNSDIVINLGKQVAVKKITIKITATTANDRNLAEISKVEFLNNVYKEIPKPEM
                     NIPKINKISTSTAVGNEKISFYWNNEVNVSAYELILDKIDSKGKVLSTKKLQTSKNTI
                     EVRDIEAYGLYRVSIQSLNGDWSSGYKDATPENLDGVPENVDSNYKPIQFSPDSILEF
                     QVVPDTKPEPPEGINVKGKFKSLDVSWKNHKQAKDFDLYYKEKGSNGSWIKYNDKLIR
                     GTSSKIEGLKDNTTYEVRMTATNHLGTSGMSKTYIGTTESMDAPTTPNYRLINTPKEN
                     GGFGIPTNHIVDVTYPAGYDKSEYSDKNPFDKFNVVDGDFTTHWTFPTYNAAEGTNRG
                     PIITFDKSYTMDTFMATPRFDVSDKTINDFEVRYWDENGQLHNLGDVPFETKTDPINN
                     NKYVMVRLKEPITATKIQVSVCSSYSYKSNISELKFYEYDSIEDDVRNLFMDDLQVEL
                     KEDVTQEKITELKDRLNTPDKASGEYHPYKTVIERELKLAQDLYNDRATLTDVTTVNQ
                     EINKLGKYKDKNGQYTVNSNNLGMQNDWQALGVAARAGDEITVYVGSKSGKTPKLIYT
                     QYYGESGAYKSGEINLNTGKNVIQLSKLHSLDIECGGSLYIRYAEDTPSGGDIKVRVA
                     GATKIPHLNLNGTINDKSPAGVSESKKKIKAYIEELAKYKDAVKGEPYYPGTNVGNSY
                     GYSEKTGVLNTTDIESDKVTLNVPATAVYQGISKGNADLNTQVDRLYNSMLAWEQIMD
                     LVYSERGVFKTQDLDGNGTVDDNEFNLTKNDMAPKSRMNIKYQRMFIGAFMYASGLHV
                     GVEYGSVPGLMNGVPFQIDDSGKATGGNLFGWGIGHEIGHVTDIGKMTYSETSNNVLA
                     LLAQTFDDKTHSRLEGSTMDKIYEHVTSNSLGIPSNVFERLGMLWQLHLAYDDDFTGS
                     MLKNNSDADLSNDTFYAKISRKYRALSSSDPINSLPKDQMLVAMASSVVEKDLRDYFK
                     AWGVEITPELNSIMDSKNYEKESRKIQYVNDEARRKILNENIASMAKDTKVSASFSDG
                     IQSGSLVKSNKISIDLDVDKDKDKILGYEIIRSDGNYLDGENGTQVKYRTVGFVDAKG
                     NSKTKFTDNISPLNNRAFTYKVVAYDYHLNPTEEFEVGTVKLSDEGKINKSAWSFITN
                     TVSDGDVRTENDSHGPLQNPEIDNIKDNDASTTYKGKIISKAEWNKDPQKDPDINVEE
                     NPYIMVDMKETLPIVGLKYTKPEAEARKFSLKGLFNFRKNTSTTYNPLTNYKIQVSND
                     KKNWEDVSQGTFEYGQDLVGGGKDQDNEARVTFNKDGKLWTYQARYVKLISNNKSNIE
                     VAELDIIGPPGDNIEIGTMNNADETRTNGIGKLAEDYVYQSDDSSTSEDETGKIPAGS
                     IVITGEYSGNPAFNLPLLIDKNNKTISGEALLFAEVPEKGELGEISKGTWVYYMPKEN
                     FDSLSDKVKAELYRYNDLQGDTPVGQRFVSDTMYVPVGAKNYDELKTISLTDSNSKAR
                     KATRNSIDISNKKVITVSNKVKGNIVRDK"
     regulatory      complement(8353..8438)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(8610..10013)
                     /locus_tag="PC465_003436"
     CDS             complement(8610..10013)
                     /locus_tag="PC465_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp9"
                     /protein_id="HDF2650709.1"
                     /translation="MKNSKKILAIGLTLFLVMVNTPMVNALTSVEQIKGNDRYETAAK
                     IADKQNYNTAILINSDNSLADGLSASGLAGALNAPILMTKQNQIPNTTMERLNKAKTV
                     YIIGSESTISKNVENQLLSKKKVVQRIFGENRFDTSIKIAEKIKEIKPIDKVIIANGF
                     TGEADAISASPVAARDGVPIILTDGNSVGFDTTGLKSYALGSSEIISDELVKSTNSIR
                     LGGTDRFETNKIVIQEFYKNSKEFYLSKGLQLTDALAASTIAKNAPVVLVENGSNKSI
                     LSGADKLTVLGGINQNVIKQCINQASPNQQGLYYNPNDRAFKERIKGKVYALTKQYRK
                     ENGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKNSYSTFLKYLDWSEIKPGYIA
                     VQGENIIKYKIPDKPVYTNRDADDIGNFIFNEWKTNPEEGTNMLHKGYEIMGFGIAIT
                     GDKNLYATHEFYGRYKE"
BASE COUNT         2790 a         1883 c         1161 g         4331 t
ORIGIN      
        1 ttatatatat aaaagatatc tgctttattt aaaattaaac ttaatatagc tcaaattatt
       61 atacatttta acctcaatat tattagattg ttaagataat gaaaataaaa taagaatgca
      121 tttaaatata taactttata tctaaataca ttcttatttt ctatttactt aatatttatt
      181 tttcaattaa actcttaatc ttgtctatta cagatgaggc tattcctcca cctacttcaa
      241 acaactttga tgaattttta ccttttaatg acgattcttg tgatttatct aacgtatttg
      301 tagcaagtat aactggtgaa ttgtttttag ctgctaatgg tccaactgct aaagcatcta
      361 taagtttatc ttgatttgca actacaactc catctagctt agattgagag tagaatttat
      421 ctattacttt ggcattcgtc tcttgtctag tttgacctgc caccctattg tttgatatat
      481 ctttgtttgc tatttttcca acttgttcaa tagccttgtt agatattttt tctactccac
      541 caataaaata tatatttgac accttatttg atttaataaa ttgttcagct tcattatcta
      601 caccatcttt ttgtgtaagt actattggag ttttttcttt accagccagt gatgctattg
      661 ataatgaatc agcttctcca tttcctgctc ctatatacaa cttgcttaca ttattcgtct
      721 tatctatttc ttttgctata ttaatagaag tttgatatct tgtatctcca cctattcttt
      781 gtactgatat ttttgaattt acagctttga tagcttcaac aactgaattt ggcattgagt
      841 tgtttccacc tatcacaatt acttttgatg gatttagcct tttcaattct tctacagttt
      901 tttgaggaag cttttcattt gatgataaaa gaattggtga gttttttaca ctagcaagtg
      961 gtgtagctgt aagcccatcc accatacttt tatcttctcc atttactatt acaactgtat
     1021 ctgattttgt ccaaccactt tgagatattt tgatagctgt ctcaaatcta tcagcacctt
     1081 ttaatttttt gactgtgaca ttagatgtag aatcacttga atttcctcct ccagagcttc
     1141 caccactaga tgagccgcct gaattacttc ctccgccatt atttccacca ttgccattat
     1201 ctggtggtaa ttcatccggt tttgataatt cattttcaac tatgtattct aaactttttg
     1261 gaagtgtaac ttcaacatat ttgtttattg tagcttttct tcccttagtt gttttttgtg
     1321 ctaatccaag ttttaatatt acatttgaac cactttcttg tgtttcttta ctaacaatag
     1381 aatagtttat cctaatattg tttaataaat attcaagtgc ttcacttttc tctaccttat
     1441 acttttcagg gtcgttttta ctagaaccag ttccaccaat cggttttact tcactctcat
     1501 taataagggt aaatattaat ccttcatcag agcttatatt ttcataatcc aatgttttgt
     1561 tgttatatgt tacaattttt aaagctggtt tatcgcttgt tccttttcct aaaactttat
     1621 agtcagcatt tgagttactg ccagattttt ttatagatat tcttcctata ttcaatctat
     1681 ttccgtctag taaatcttca tttgatgtaa catatatatc taatgtagtt gtattacttg
     1741 atttgttgta ttctgctcta caagtagcat ttgcatttcc actttttatc tgagatttta
     1801 tattatcaga ccaagtaatc ttttctttct gctcattatc tactacttca acctcacctt
     1861 gtacttttat actggcttga aatgaatata ctatgttttc tactgagtcc acagatatat
     1921 ctatagtatt tactttctca tacgtttttg ttccttgtaa aactggagct gcatatgcac
     1981 atgtagcact accagttaca gctactgcca tagttgatac tgctatagtt cttataaaag
     2041 attttctttt actcattaac acccgtcctt atctatcatt aactaagtgg ataaatttac
     2101 ttatccacct agcttttata tttaatttat aaattaccct aaacttatag ttacatttat
     2161 atactttact tttaatatct actattttaa aactattcta gtacctaatc ttattagata
     2221 tacaatgtta gtgttagtat ttttacgttt ttagagttcc acctactatt tatctctaac
     2281 aatattaccc tttactttat tgcttacagt tataaccttc ttattactga tatcaataga
     2341 atttcttgta gcttttctag ctttactatt actatcagta agacttattg tctttaactc
     2401 atcataattc ttagctccta caggtacata cattgtatca cttacaaatc tttgacctac
     2461 tggagtatct ccttgaaggt cattgtatct atatagttca gccttaacct tatcacttaa
     2521 agaatcaaag ttttcttttg gcatatagta aacccatgta cctttactga tttcacctag
     2581 ttcacctttt tctggaactt ctgcaaataa aagcgcttct ccagatatag tcttattgtt
     2641 tttatctata agtagtggta aattaaatgc tggatttcca ctgtattcac ctgtaataac
     2701 tattgaaccc gctggaatct tacctgtttc atcttcactt gtgctagagt catcactttg
     2761 atatacataa tcttctgcta attttccaat tccattagta cgagtttcgt ctgcattatt
     2821 cattgtgcca atttctatat tatcacctgg aggtcctatt atatctaatt ctgcaacttc
     2881 tatattagac ttattatttg agattagttt tacatatcta gcttggtatg tccaaagttt
     2941 accatcttta ttaaatgtaa ctctagcttc attatcttgg tcttttcctc caccaactaa
     3001 atcttgtcca tattcaaaag ttccttgact tacatcttcc cagttctttt tatcattact
     3061 tacttgtatt ttgtaattag ttaaaggatt gtatgttgtg ctagtatttt ttctaaagtt
     3121 aaataatcct tttaatgaga acttcctagc ttctgcctct ggttttgtat attttagtcc
     3181 tactataggt aatgtttctt tcatgtctac cattatatat ggattttctt ctacatttat
     3241 atcagggtct ttttgagggt ctttgttcca ctctgcttta cttattatct ttcctttata
     3301 tgtagtactt gcatcattat cttttatatt atcaatttca ggattttgta atggtccatg
     3361 tgagtcattt tcagttctaa catcaccgtc agaaacagta tttgttatga atgaccatgc
     3421 tgatttattt attttccctt catctgataa ttttacagta ccaacttcaa attcttctgt
     3481 tggatttagg tgataatcat atgcaactac cttatatgta aatgctctgt tattaagagg
     3541 agatatatta tcagtaaatt tagtcttact atttcctttt gcatccacaa atccaactgt
     3601 tctgtatttt acctgtgttc cattttcacc atctaaataa tttccatcac ttcttattat
     3661 ttcgtatcct agtatcttat ctttatcctt atctacatct aggtctatag atattttatt
     3721 agatttaact agagaaccac tttgtattcc atcagaaaaa ctagcactta ctttagtatc
     3781 ttttgccata ctagctatat tttcatttaa aatctttctt ctagcttcgt catttacata
     3841 ttgtatcttt cttgattctt tttcgtagtt cttactatcc attatactgt ttaattctgg
     3901 tgtaatttct actccccatg ccttaaagta atctcttaaa tctttttcaa caacacttga
     3961 tgccattgct actagcattt ggtcttttgg taaactatta attgggtcac tacttgaaag
     4021 tgctctgtat tttcttgaaa tctttgcata gaatgtatca ttacttaaat cagcatctga
     4081 gttattcttt aacattgaac ccgtaaaatc atcatcataa gctagatgta attgccataa
     4141 cattccaagc ctttcaaata cattgcttgg tatacctaag ctatttgaag ttacatgctc
     4201 atatatctta tccattgttg aaccttcaag tcttgaatgt gtcttatcat caaaggtctg
     4261 agcaagtaaa gcaagtacat tgttactagt ttcgctatat gtcatctttc caatatctgt
     4321 aacatgtcct atctcatgac ctattcccca tccaaataag tttcctcctg tagcttttcc
     4381 actatcatct atttggaaag gtactccatt cataagccct ggaactgaac catattctac
     4441 tcctacatgt aatccagaag catacataaa tgctccaata aacattcttt ggtattttat
     4501 gttcatacga gattttggag ccatatcatt tttagttaag ttaaattcat tatcatctac
     4561 agttccatta ccatctaaat cttgtgtttt aaatactcct ctttctgagt aaactaaatc
     4621 cattatttgt tcccatgcaa gcatactatt atataatcta tctacttgtg tatttaaatc
     4681 agcatttcct tttgatatcc cttgatatac agctgttgca ggaacattta atgttacttt
     4741 atcactttca atatctgtag tgtttaacac accagttttt tctgaatatc catatgaatt
     4801 accaacattt gttcctggat aatatggttc tccttttaca gcatctttat atttagctaa
     4861 ttcttctata tatgctttta tctttttctt agattcagaa actcccgcag gactcttatc
     4921 atttattgtt ccatttagat taagatgtgg tatcttagta gctcctgcta cacgtacttt
     4981 tatatctcct ccacttggag tatcttcagc gtatcttatg tataaacttc ctccacattc
     5041 tatatctaaa ctatgaagtt tgcttaattg aattacattt tttccagtgt taagatttat
     5101 ttctccactc ttatatgcac cagattctcc atagtactgt gtatatatca acttaggagt
     5161 ttttccactt ttacttccaa catatactgt gatttcatct cctgctctag cagctactcc
     5221 taatgcctgc cagtcatttt gcatacctaa attattggaa tttacagtat actgtccatt
     5281 tttatcttta tattttccta atttatttat ttcttgattt acagtagtta catcagtaag
     5341 tgtggctcta tcattatata agtcttgagc taattttaat tctctctcaa taactgtctt
     5401 atatggatga tattctccac tagctttatc tggagtattt aatctatctt ttaattcagt
     5461 tattttttct tgagttacat cttcttttaa ttcaacttgt aggtcatcca taaatagatt
     5521 tcttacatca tcttctatac tgtcatactc ataaaactta agttctgata tattagactt
     5581 atatgaatag gatgagcaaa cacttacttg tattttggta gcagttattg gttcttttaa
     5641 tctaaccatt acatacttat tattatttat agggtctgtc tttgtttcaa aaggaacatc
     5701 ccccagattg tgtaattgac cattttcatc ccaatatcgt acctcaaagt catttattgt
     5761 cttatcagaa acatcaaaac gaggtgtagc cataaaagta tccatagtat aagatttatc
     5821 aaaagttatt attggtcctc tattcgttcc ctcagctgca ttatatgttg ggaatgtcca
     5881 atgtgttgta aagtccccat ctactacatt gaatttatca aatggatttt tatcactata
     5941 ttcacttttg tcatatcctg ctggataagt aacatctaca atgtgatttg ttggtattcc
     6001 aaatccacca ttctctttag gagtattaat taatctatag ttaggtgttg ttggtgcatc
     6061 catgctttca gttgtaccta tatatgtttt agacattcca ctagttccca agtggttagt
     6121 agctgtcatt ctaacttcat atgttgtatt atccttaaga ccttctatct ttgaacttgt
     6181 cccacgaata agcttatcat tgtattttat ccaagaccca ttagaacctt tttctttata
     6241 gtacaagtca aagtctttag cttgtttatg atttttccag cttacatcaa gagatttaaa
     6301 tttaccttta acatttatac cttctggtgg ttctggtttt gtgtctggaa caacttgaaa
     6361 ttctaatata ctatctgggc taaattgtat aggtttatag tttgaatcta cattttctgg
     6421 tactccgtct aagttttctg gtgttgcatc tttataacca ctagaccaat ctccatttaa
     6481 agattgtatg ctaaccctat atagtccata tgcttctata tctctaactt ctattgtatt
     6541 tttactagtt tgtaattttt tagtagataa tacttttccc ttactatcaa ttttgtctag
     6601 tataagttcg tatgctgata catttacttc attattccaa taaaaagata ttttttcatt
     6661 tccaacagca gtgctagtcg atattttatt tattttaggt atattcatct ctggttttgg
     6721 tatttcttta tatacattgt ttaaaaattc aacttttgat atttctgcaa gatttctatc
     6781 atttgctgtt gtagctgtta tttttatagt tatctttttt actgctactt gtttaccaag
     6841 atttattact atatcactat tttgaacatc tgcatatgtt tctaatgctg acctactata
     6901 tgtagatgtt gtaaagttat catctttact gatattatcc ccttcttttg gagtatcttc
     6961 atctgaatta ggtttatcca ttgatgaatt ttctttatca ttatttttat cttgattggt
     7021 attagagttt gcttcttgtt tatcgctatt ttcctgttgt ttatcattat tttcatcttt
     7081 attatttgag ttattatcag tctggtttat attttcatct ttattattta cttcttcttg
     7141 atttacttct tcttgttcgt tatttacttc ctcttgttgc tcctcatctt ttaagttttt
     7201 catatattct ttgttttcat aaggaatctg ttgaatatta ccatctttgt cagtaacctc
     7261 aactattcct tttgctggag cagtaccttc tggagctttt atattgatga cttccatatt
     7321 aagtgcttct gataaagcta tatccattac tgctggtttt tcctcagata tttcatcatt
     7381 ttttgaagat attgtaactc cattattttc tccactaaat aaattttcta cattaccatt
     7441 aatatctaca tcactatttc cttttaattc aaccttactt gtatctacta taggattggt
     7501 agatactata ctttctaggc tttttgcatc ttcactttgt cctaaatttt tctgtacata
     7561 atctaagtca acaatatcta cctttccatc tctatttaaa tcaaattctc ttttatttga
     7621 atctatattc tctaaaacct tattataatc actcttatct actttaccgt ctccatttac
     7681 atcacccatt aagaataatt cataatttaa aggtttattt ttattatcta cacttgctct
     7741 attgcttaat aagactcttt gtgaataact tgatatatca atgtctttaa tttctttgtt
     7801 cttaaatcca gctccagaga cttctacatt gtattttcca acaggtaaat tattaaatac
     7861 aatattataa tatgatatat tctcatcttt attttttatt tcacttctac ttgcagataa
     7921 tttttttata gtatattcta tattatctgt cccaacattt actgttcctg aatctttttc
     7981 tccaagcttt attattccac tattgttact atcatctttt aatcgtaact gcatattagt
     8041 catactttct gactcgctat tttttattgg cagtgaaaaa tttaaatcta cttcaagact
     8101 cccccttaac ttttctgtaa ctgatttttc aactgccctt agcttcccct ctaatatagg
     8161 ttctgcaaaa acgtttagtg gtgcactaca catagatact gctagtacac aagatattgc
     8221 ctttttcatg aaataacaat cctcccttaa taaatatcta atttttcatg aatttaaata
     8281 ctataagttt cagacaataa aaaaagacac tcaaagagaa tcttaattat aaaataaaaa
     8341 gactttactc tttttagcaa ctggctgata tggctttaaa agctttaatc cctatagttt
     8401 tgcgtcatta gatttcccta attttgccat ttaattttca ctactttctt acccatttta
     8461 tactatattt aaacttttta atacaatttt tttagattaa attataaaaa aataacattt
     8521 atattaattt attaatataa atgttatttt ccattataat ttaattattt atatagcttc
     8581 cttacaagca taattttgtg tatattttct tattctttat atcttccata aaattcatgt
     8641 gtagcatata gattcttatc tcctgttata gctataccaa atcccattat ttcataccct
     8701 ttatgcaaca tattagttcc ttcttctgga tttgtcttcc actcattaaa aataaagttt
     8761 cctatatcat ctgcatctct atttgtatat acaggtttat ctggaatttt atatttaatt
     8821 atattttcac cttgaactgc tatatatcca ggtttaatct cactccaatc taagtatttc
     8881 aaaaaagtag aatatgaatt ttttccattt atcgtatgag ataaagtctt cttatttgcc
     8941 attaaattag accaatcatt tgctagaccc tctaatctgc ttgctacaga taacgctctt
     9001 actccattct cttttctata ctgctttgta agagcatata ctttaccctt tattctctct
     9061 ttaaatgctc tatcatttgg attgtaatat aaaccttgtt gatttggtga agcttgattt
     9121 atacattgct tgataacatt ctgatttatg cctcctagta cagtcaattt gtctgcacca
     9181 cttaaaatac tcttgttact gccattttca actaaaacta caggagcatt ttttgctatt
     9241 gtagaggcag ccaaagcgtc tgttaattgt aagcctttac ttagataaaa ttctttacta
     9301 tttttataaa actcttgtat aactatctta ttagtttcaa atctatctgt gccacccaat
     9361 ctaatagaat ttgtgctctt aactaattcg tcgctgatta tttcactaga accaagcgca
     9421 taactcttta agcctgtcgt gtcaaatccc acactatttc catctgtaag tattataggt
     9481 actccatctc tagcagctac tggtgatgca cttatcgcat ctgcttctcc tgtaaatcca
     9541 ttggctataa ttactttatc tattggctta atttctttga ttttttcagc tatttttata
     9601 cttgtatcaa atctattttc accaaatatt ctttgtacaa ccttcttttt ggatagtaac
     9661 tgattctcaa catttttact tattgttgat tctgagccta ttatatacac agtctttgct
     9721 ttgtttaatc tttccatagt tgtgtttgga atctggtttt gttttgtcat caaaataggc
     9781 gcatttaagg ctccagctaa accacttgca cttagaccat ctgctaagct attatctgag
     9841 ttgattagta ttgctgtatt gtagttttgc ttatctgcta tttttgctgc tgtctcatat
     9901 ctgtcattcc cttttatttg ctcaactgat gtcaacgcat ttaccatagg agtatttacc
     9961 attactaaaa atagtgtaag tcctatagct aatatctttt tactattctt catattattt
    10021 tctaccccca atgtactttt catatttttt attagtactc atacttattt ttaatcaaaa
    10081 gttacaattt tgttaccata ttttatatat gataccatag ttatccatac aactcaaaca
    10141 atatacctaa agtttttatt ctcta
//
LOCUS       DAMJXI010000103         9883 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.110, whole genome shotgun sequence.
ACCESSION   DAMJXI010000103 DAMJXI010000000
VERSION     DAMJXI010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9883
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.110"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(335..1606)
                     /locus_tag="PC465_003437"
     CDS             complement(335..1606)
                     /locus_tag="PC465_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2650710.1"
                     /translation="MLKVLKGNIIFTKTSETFTVFENSYIILEKGKVKGIFKEIPKEY
                     KNLKVVDYTDKLIIPGMNDLHAHASQFKNLGMAMDKELLPWLETYTFPEESNYKDIEY
                     ATKMYKKFVKELWKSGTTRIAVFATVHKEASMKLMDIFKEVGLGAYVGKVNMNMNCPD
                     TLLENTQDSITDTEEIINKYSDTDSIVKPIITPRFIPSCTSELLKGLGDLCLKYNIPI
                     QSHLSENYDEIEWVRSLEPESKFYGDAYNRYNLFGQTPTLMAHCVHCSQDEIDLMREN
                     NVMAVHCPASNFNVGSGAMPIRKLIDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKL
                     YWVNSGKKYNFLSLSEAFYIATKSGGSFFGKVGSFEEGYDFDALIIDDSNLNHDNYSI
                     LERLERFIYVGDDRNIIHRYVCGKLIEEPNI"
     repeat_region   2253..3663
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=2253..2281
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaat"
     gene            complement(4898..5449)
                     /locus_tag="PC465_003438"
     CDS             complement(4898..5449)
                     /locus_tag="PC465_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2650711.1"
                     /translation="MSINTVIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDS
                     NPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPT
                     RNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAE
                     SIHTYHNQGEKTLKAVIINYYPV"
     gene            5640..6602
                     /locus_tag="PC465_003439"
     CDS             5640..6602
                     /locus_tag="PC465_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HDF2650712.1"
                     /translation="MRVLNNVTEAIGNTHMLHLSKIADEFGVQGNIYAKMEYLNPGFS
                     KKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSM
                     ERARMMKALGAEVVLVDQMPNSVHGQVSGEDLALVEIEAQKIAKERNAFRADQFNLEA
                     CNHAHEKYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKTLKKHNSSIKCYVVEPETA
                     AIYSGKEITDQGHKIQGGGYSMDLPLVDKKLIDGYIQVTDEEATDVARKLAKLEGVFA
                     GFSSGANVCAAIKLLKSSEKGKNIILTLNDSGLKYLSTDLYEEL"
     gene            6897..8741
                     /locus_tag="PC465_003440"
     CDS             6897..8741
                     /locus_tag="PC465_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDF2650713.1"
                     /translation="MQKRILRNFIFTGKNILNKLVFIIKYNFSTLILFELFHKGLALF
                     FIWPSIRYIFDILIKSLHIVYLNMDNFIKVLTNPMSIVLIILSVIILAFYAFFEFTSV
                     IICLNKSIKYEKIGLFELFKISFENSIKLLYPKNILLFIFVILIIPLVNTVLISGFIG
                     KIQIPEYILDYIKSDIILNIIYMIFLLIIYISVIRWIFSIHEITLNTENFKRARKESV
                     NLIKGKIIRTIIYSLILSLVVAIIGYAIYHSGIIFIGIWTKYCTDMEFLKNVFINRCI
                     AFEEYFRLILSIFIFILDIGFISATYYQYKGVSISKNNIKKEKKSISKIVFNLVLILL
                     ISYIESVAFSSHINGMFNTSFSFYTTAIAHRAGAEMAPENTLAAIKEASHAKADYAEI
                     DVQEAKDGELIVLHDSNFKRTTGVDKNVWDVNYNEVKTYDAGSFYYYGKGYYDEKFVG
                     EKIPTLKEMIKYSKGKVKLLIEIKLNGHEKGDVVKKVVQLIKENNFENQCIVASMDKT
                     ILQKVKKLDENLLTCYFMAIAYGDFSKLNYVDMYGIESTFVNKTVVEKIHKMNKKIFV
                     WTVNSDSLIEKMLDLNVDSIITDNPYLIESAIYWKKNGFISQVSDYLF"
     gene            9063..9647
                     /locus_tag="PC465_003441"
     CDS             9063..9647
                     /locus_tag="PC465_003441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDF2650714.1"
                     /translation="MTEREKMLAGELYDCGDIELLTQWHKAKDLVRDYNQTDSSDLEK
                     KEKILNELLGGKGKNLWITAPYYVDYGNNIYFGNNCEVNMNCTFLDDNKIIIGDNALI
                     APNVQIYTAFHPTNAGDRFGNAKEDGSFEFCKTQTAPVTIGDNVWIGGGAIIMPGVTI
                     GDNVVIGAGSIVTKDIPSNMIAYGNPCRIIRENK"
BASE COUNT         3747 a         1039 c         1447 g         3650 t
ORIGIN      
        1 gaaaatatag gagattagaa gtgtttgata attacagtac atgttagata tatcattgta
       61 aattaacata gctttgaata taataatgtt caaaaggcaa tatttttgag gtctgaatcc
      121 aataataata tagtcttatg attgtagata tcaaaaaata taagttacta agaatacgtt
      181 ttgtagattt atatatgatt aataactaaa gctataaata aacaaaataa aaagagtatg
      241 tttcaaccta tagcttttag atttaaaata tactctttta ttaattatag ttgtataaat
      301 taaccataat atataattaa aatttttatt ataattatat attaggttct tcaattagtt
      361 ttccacatac atatctatga atgatatttc tatcatcacc aacatagata aatctttcaa
      421 gtctttcaag tatagaataa ttgtcatgat ttaaatttga atcatcaata atcaatgcat
      481 caaaatcata accttcttca aagctaccaa cttttccaaa gaaacttcca ccacttttgg
      541 ttgcaatata aaaagcctca gataaagata agaaattata cttcttacca gaattaaccc
      601 aatataattt agataattgt attgcagata ccattgcttt aaatattgac aatgtatgtc
      661 caccgcttat atctgatcca agtgctaatc taatattatt atcgattaat tttctgatag
      721 gcatagcacc actaccaaca ttaaagttag aagctggaca gtgaactgcc ataacattat
      781 tttctctcat taaatctatt tcatcctgag aacaatgaac acaatgagcc attaaagtag
      841 gagtttgacc aaataaatta tatctattat atgcatctcc atagaattta gattcaggtt
      901 ctagacttct aacccattca atctcatcat aattttcaga taagtgtgat tgaataggaa
      961 tattatattt taaacataaa tctcctaaac cttttaaaag ttcacttgta cagcttggta
     1021 taaatctagg tgttattatt ggttttacaa tagaatctgt atcactatac ttatttataa
     1081 tttcttctgt atcagtaata gaatcctgag tgttttctaa taaagtatca gggcaattca
     1141 tattcatatt tactttacca acgtatgctc caagaccaac ttctttgaat atatccataa
     1201 gtttcataga ggcttcttta tgtactgttg caaacactgc tattcttgta gttccagatt
     1261 tccaaagttc ttttacaaat tttttataca tttttgttgc atattctata tctttataat
     1321 ttgattcttc tggaaatgta taagtttcaa gccatggcaa aagctcttta tccatagcca
     1381 ttccaagatt tttaaattga gaggcatggg catggaggtc attcatacca ggtattataa
     1441 gcttatcagt gtaatctact acttttaggt ttttgtattc cttaggtatc tctttaaata
     1501 ttccctttac tttacctttt tccagtataa tataactatt ttcaaatact gtgaaagttt
     1561 ctgaagtttt tgtaaaaatt atatttcctt ttaatacttt taacatatag gtctccttag
     1621 ttttaaattt gttttaatat atgtaggtaa aattttgttt tacaaatcaa aattttacca
     1681 catgtattat atcaaatcta aactataaat actattagat aatagcaaat attagtgcaa
     1741 tacagttgtt tactattatt atatataact gacatttaag tgacatttaa gaaaaatata
     1801 atgcctactt acataaaatg gaatgttatt taaagagaac tttgattata ttttcagaag
     1861 cttttttatc catatcgttt aaaacaagaa aatatctatt catagttatt tttatattag
     1921 tatgtcctaa tctttcagag atgattttta tattagttcc agctagaaga agaattatta
     1981 gaatagataa tatagtaagt atttacaaat atgtaggtgt tcttaaattg ataaattatt
     2041 ccattttaat tttatagttt gaattttatg atataataaa aatatataaa ttttgcagtg
     2101 agcgatattt ttgataaagt agggtttaac agttgcaatg taagggattg agggtgtgtg
     2161 ataaatgtta tcaattgcac tactcatggt tcactgcaaa tttgagagag ttgtatgtgt
     2221 gtaagtactg aaaatactta gtttattttg gggttttata ttaactaagt ggtatgtaaa
     2281 tcaaagaagc tccaccccat ctgtttttta ttatagcgtt ttatattaac taagtggtat
     2341 gtaaattgtt ttccatgaac atttcgagct gacttttatt gtgttttata ttaactaagt
     2401 ggtatgtaaa taacttcttg ttttttcttt aaaacacgta cttggtcgtt ttatattaac
     2461 taagtggtat gtaaataaat caatgccaac tataggaacg tcgggattaa ttggttttat
     2521 attaactaag tggtatgtaa atggagtata aggtaaatcg taagcaactc cagaaagagg
     2581 ttttatatta actaagtggt atgtaaatga attacaatat tatctccagc atcaagacta
     2641 ggatgtttta tattaactaa gtggtatgta aatctgatag aaaaagaaga ttatttgaaa
     2701 gttgagacta gttttatatt aactaagtgg tatgtaaata aagattgcaa tagatttcct
     2761 gttaaaatag gtacaggttt tatattaact aagtggtatg taaatactga acctactagc
     2821 attgtagggt tgaagtctac aagttttata ttaactaagt ggtatgtaaa ttctttttca
     2881 aattgcatag ttggttatac ttattataag ttttatatta actaagtggt atgtaaataa
     2941 atatgtaagt tttaatttaa aatgatattc aactgtttta tattaactaa gtggtatgta
     3001 aataatattt agagatggcg tagagtgtta aaagtttcag ttttatatta actaagtggt
     3061 atgtaaatga aataataaat agcattgtcg aatggtttgc aagccgtttt atattaacta
     3121 agtggtatgt aaattatagc taattattag attcaatttt aatttcgtta agttttatat
     3181 taactaagtg gtatgtaaat attgcaacac ttcatcagtt gataaatata gtatattgtt
     3241 ttatattaac taagtggtat gtaaatttat acatatttgt agctccttgc tgaactgttg
     3301 cagttttata ttaactaagt ggtatgtaaa ttggttaaat ctccaacaga acatttatct
     3361 aaattacaag ttttatatta actaagtggt atgtaaatct tgttaatgca aataaacaac
     3421 atagcactat taatagtttt atattaacta tgcggtatgt aaatagggtt tctgataaaa
     3481 tcttcaaaca tgtaaaatat gtgttttata ttaactatga ggtatgtaaa tcttatactt
     3541 agttagaact atatatcgac acaaatatgc tttatattaa ctatatggta tataaattgc
     3601 aatttttatt cgttgtccaa tctctttgaa atttgtttta tattaactaa gtggtatgta
     3661 aatttgcaac aagtataggt aaaatacccc aataatttat acagcatttt ctcctttaaa
     3721 atataattat tttttagcat ttgtagtaaa taattaccag ataacattga ctttagtttt
     3781 aatgattaaa atataaaagt agaataatta taaaaagtat tgaaaaattt ataaatatat
     3841 ataataaaac ttaatgacaa gatattagat ataaaaaata attaccttat aaatagattg
     3901 aaatttatga atattcatac tataatttaa atataaggag atgccatttg aaaataaaaa
     3961 ttaaaaaata tttaatgcta ctacaatagg aactagaact acacttaata aatatacaga
     4021 aattagattt ggctcaatat aaaatacaaa tatagaattt aggtgttttt tatgaaaaaa
     4081 attttatatg ctttatatag tttcattgtt attatagcta attttagatt aaaagaaaaa
     4141 aattataact ttattttatt agcaatcttt tttatattgc tgttaattca aaatggagtt
     4201 ttaaaaacag gttatcaaaa tagagctaca ttttatcaag ataattattt taatggagag
     4261 gataaaaatg ataagataaa atttatgact ataaagattt ttatattttt gtcattacca
     4321 ttatgtttta atatactatt caattattta acctcttaaa ttatatttag atataggagt
     4381 cttatgataa aagtaagctt atgtgttatt tgtagtaaat ataaagtgca tatagtgata
     4441 aaacaaaagt ttcatataaa tgaagaaaaa aatataaaat aatttattta actacttaaa
     4501 aataaactaa aagggataat aaaatagctt ttaggttatg gtaataaagg tatttaaaaa
     4561 gagtgcataa gcactccaat tgtgagaaat acatacacaa atcattatta caacaatgaa
     4621 aaatgtacat ataagagacg ttttgtattt gttttaagtg ataatatttt aatactaact
     4681 aaataattat cacaatagta aaaaagaaaa aggagtattt tgtactccat ttgtcaaaaa
     4741 tataaaactt ttatataagc ttattataac ataattgata aaagtgtaaa gatatataat
     4801 gaatttataa agaaaaataa aataaaaaag ataaatccta atcaaaggat ttatcttttt
     4861 gtatagaaaa taattattct attattaaat ggcatggcta aactggataa taatttatta
     4921 ttactgcttt caatgttttt tctccttgat tatggtatgt atgaattgat tcagctgaaa
     4981 aacaaataga gtcattttct ctaagttgat aaatagagtc atttacttct aattttaatt
     5041 gaccttctat aatcataata tattcctgtg atttttcaga atgaccaaca gatgtataac
     5101 tatgaccttc ttctaattcc atttgaaata attcgaagtt tctagttggt gtattgggat
     5161 aataacaata aagacgataa tctttatttt ctgaaacttg tacatctata tcagtttttg
     5221 atacaataaa agtttcattt tgaggttgtt ccagtattgc agtatatgga acatttagtc
     5281 cacttgcaat tttccaaatt gtgtttactg ttgggtttga gtctcccttt tcaatttgag
     5341 aaagcattac tttacttacg ccagataatt cagcaagttg acctagactt aagttacgtt
     5401 cattacgtaa tctatttaaa tttttagcaa taacagtatt aatactcata gtaactcctt
     5461 aaaatgtaaa ttattgacaa atataattta cgaatgtata atttatttaa cattatttat
     5521 aatttacaaa tgtataatat aatgaacgtt aaatacactg tacatccgta atataaatta
     5581 tactgcataa agagttgttt ttcaacggat gatagttgag agattaaggg ggaattgtaa
     5641 tgcgtgtact taataatgtt acagaggcta taggcaatac tcatatgtta catttatcca
     5701 aaatagcaga tgaatttgga gttcaaggta atatttatgc aaagatggaa tacttaaatc
     5761 cgggatttag taaaaaggac cgtgtagcat tacaaatgat taccgaagca gaaaatgcag
     5821 gtttattagt tccaggtcaa gcagttgtgg aattaacaag tggtaatact ggaacaggac
     5881 tagcaatagc ttgtgcatgt aaaggatata aatttatagc gtgtatgtca aaaggaaatt
     5941 ctatggaaag agcaagaatg atgaaagctt taggtgctga agtagttctt gtagaccaaa
     6001 tgcctaattc agttcatgga caggtatctg gtgaagattt ggcacttgta gaaattgagg
     6061 ctcaaaaaat agcaaaagaa agaaatgcat ttagagcaga ccaatttaat ttagaagctt
     6121 gtaatcatgc acatgaaaag tatacagcag aagaaatgtg ggaacaattg gatggaaata
     6181 ttgatgtatt tgtagatttt cttggaagtg gtagtacttt tgcaggatgt tcaaaaacac
     6241 ttaaaaaaca taattcttct atcaaatgtt atgttgttga acctgaaaca gcagcaattt
     6301 attcaggtaa agaaataact gaccaagggc ataaaataca aggtggagga tattctatgg
     6361 atttgccatt agtagacaag aaacttattg atggttatat tcaagttaca gacgaggagg
     6421 caactgatgt agcaagaaaa ttagctaaat tagaaggtgt atttgcagga ttttcttcag
     6481 gggcaaatgt atgtgcagca attaagttgt taaagagcag tgaaaaagga aaaaatataa
     6541 ttttaactct taatgatagt ggtttaaaat atttaagtac tgatttatat gaagaattgt
     6601 aataatagca caatagttat gcaatgtttt ttaaattaag tatatagatt taaattataa
     6661 aaagtatctc aatgtaattt ttgaaagtta taaaggagat acttttttat tttgtaaata
     6721 tggagtatcc tacttataag tattaagcta tatagatatt gatgattagc tatgcaataa
     6781 aaaagagtat gtgtttttgc atttatacat cataacttgg aataatacat attaatgttc
     6841 taaatgtatt taaaatatat gataaaatta gaacaaatag atacaaggag ataaaaatgc
     6901 aaaagagaat tttaagaaat tttatattta cgggtaaaaa tattttaaat aaacttgttt
     6961 ttataataaa atataatttt agtacattaa ttttatttga attatttcat aaaggattag
     7021 ccttattttt tatatggcca tctattagat atatatttga tattttaata aaaagtttac
     7081 atatagtcta cctaaatatg gataatttta taaaagtttt gaccaatccc atgtcaatag
     7141 ttctgataat actatcagtt ataatactag ctttttatgc attttttgaa tttacctctg
     7201 taattatttg tttaaataaa tcgataaaat atgaaaaaat agggttattt gaactcttta
     7261 aaatatcatt tgagaactct ataaaattgt tatatcctaa aaatatacta ttatttatat
     7321 ttgtgatatt aataattcca ttagtaaata cagttttaat ttcagggttt ataggaaaaa
     7381 tacaaatacc agagtacata ctagattata taaagtctga tataatttta aatataatct
     7441 atatgatttt tcttttaata atatatattt cggttattag atggattttt agcattcatg
     7501 agataacttt aaatacagaa aattttaaaa gagcaagaaa agaaagtgtt aatcttataa
     7561 agggaaagat tataagaaca attatttatt cattaatatt atctttagta gtagctatta
     7621 ttggatatgc gatttatcat agtggaatta tatttatagg catatggact aaatattgta
     7681 ctgatatgga atttttgaag aatgtattta taaatagatg tattgcattt gaagaatatt
     7741 ttagattgat tttatcaata ttcattttta tattggacat tggatttatc tcagcaactt
     7801 attatcaata taaaggagta agtatttcta aaaataatat taaaaaagag aaaaaatcta
     7861 tatcaaaaat tgtttttaat ttagtattaa tattattgat ttcttatata gagtcagttg
     7921 cattttcttc acatataaat ggtatgttta atacgtcatt ttcattttat acaacagcaa
     7981 ttgctcatag agcaggagct gaaatggctc cagagaatac tttggcagca ataaaagaag
     8041 cttcacatgc taaagctgat tatgcagaaa tagatgttca agaagctaaa gatggagaac
     8101 ttattgtact tcatgattca aactttaaga gaactacagg agtagataaa aatgtttggg
     8161 atgtaaatta taatgaagta aagacatatg atgcgggaag cttttattat tatggaaaag
     8221 gttattatga tgaaaagttt gttggggaaa agataccaac actcaaagaa atgataaaat
     8281 attctaaagg taaggtgaaa ttattaatag aaataaaact taatggacat gaaaagggag
     8341 acgtagtaaa aaaagttgtt cagttaatta aagaaaataa ttttgaaaat caatgtatag
     8401 ttgcatctat ggataaaact atattacaaa aagtaaaaaa actggatgag aatttattga
     8461 catgctattt tatggcaatt gcatatggtg atttttcaaa gttaaattat gttgatatgt
     8521 atggaattga atcaactttt gttaataaaa cagtagtaga aaagattcat aaaatgaaca
     8581 aaaaaatctt cgtttggact gttaatagtg acagtttaat tgagaaaatg cttgacctaa
     8641 atgtagatag tattattaca gataatccat accttataga gagtgcaatt tattggaaga
     8701 aaaatggatt tattagtcaa gtgtcagatt atttatttta aatattctat aattgtatta
     8761 tccagtaaaa gagatattat taaaatcaat aatatctctt tttaacataa ataaggttgt
     8821 taaattaagg ttattcttat aaaaattgtg cttatcagct ataaacaagg aataaaagtg
     8881 aaaaaattgc tctgagatta ttacagttaa aagagtttta agatgacaga gagatagatt
     8941 gtcaactgta tatttaataa atcttgttat ttattaaatt ttatataagt aaaatatata
     9001 aattaataaa tcttatgcta gaatatatat gaaaaacaat ataaatttgg aggattaaaa
     9061 acatgacaga gcgagaaaaa atgttggcag gagaacttta cgattgtggt gatattgagt
     9121 tgttaactca atggcataaa gcaaaagacc tagtaagaga ttataaccaa acagattcct
     9181 cggatttgga aaaaaaagaa aaaatattaa atgagttact tggtggtaag ggtaaaaact
     9241 tatggattac tgcaccgtat tatgtagatt atggaaataa tatttatttt ggaaataatt
     9301 gtgaagtcaa tatgaattgt acgtttttag atgataataa aattatcatt ggggataatg
     9361 cactaatcgc accaaacgta caaatatata ctgcatttca tccaactaat gctggtgata
     9421 gatttggtaa tgccaaagaa gatggttcat ttgaattttg taaaactcaa acagctccag
     9481 ttactattgg agataatgtt tggattggcg ggggtgctat tatcatgcca ggtgttacta
     9541 ttggagataa tgtagttata ggtgcaggaa gtattgttac aaaagatatt ccaagtaata
     9601 tgattgcata cggaaatcca tgccgtatta ttcgagaaaa taaataaagt taaattttct
     9661 tgcaaaatct caaaaaacac ctttcttact ttatacatag ggtattttct aatactttca
     9721 catccatatt catttgttaa atttttgtgg aatgtagttt ttatcacttc tatcttacat
     9781 ttccaccatt tttttataaa agtcattcct ttatatattt atttataata gtatatattc
     9841 tatttgatgt ttgaataagc acttattttt aagtaaaata cta
//
LOCUS       DAMJXI010000104         9864 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.111, whole genome shotgun sequence.
ACCESSION   DAMJXI010000104 DAMJXI010000000
VERSION     DAMJXI010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9864
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.111"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(74..1693)
                     /locus_tag="PC465_003442"
     CDS             complement(74..1693)
                     /locus_tag="PC465_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2650715.1"
                     /translation="MLRQATQNLITALYPRLSHEDELQGESNSISNQKRILETFAKQN
                     GFANLRWYTDDGYSGANFQRPGFQAMLADIEAGKVGTVIVKDMSRLGRNYLQVGFYTE
                     MLFPQKGVRFIAVNDNVDSANGGMDNDFTPLRNLFNEWLVRDTSKKIKAVKRAKGMSG
                     KPVTSKPVYGYLMDEDENYIVDEETAPVVKQIYQLCLAGNGPTKIARMLTEQQIPTPG
                     TLEYRRTGSTRRYHPGYECKWATNTVVHILENREYTGCLVNFKTEKPSYKTKHSIENP
                     IEKQAIFPNHHEPIIDTETWERVQELRKQRKRPNRYDEVGLFSGMLFCADCGHVMYQQ
                     RYQNKTRKQDCYICGSYKKRTRDCTAHFIRTDLLTAGVLSNLRQVTEYAAKHESRFVK
                     LLIQQNEIGGKRKTAVATKQLEQAQERISEVSRIIKRLYEDNVNGKISDERFMELSAD
                     YEQEQRELKDRAAALQEELDKSQAATVNAEKFMGIVRKHLAFEELTPTLLREMIEKIV
                     VHECSYDENGTRRQDIEIYYSFVGKIDLPET"
     gene            complement(1805..1993)
                     /locus_tag="PC465_003443"
     CDS             complement(1805..1993)
                     /locus_tag="PC465_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002571011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-encoded TnpW family protein"
                     /protein_id="HDF2650716.1"
                     /translation="MADNKQHDTRTARRPDCVTEIRMGNSVLVVSGYFKKDTTTTAAD
                     KMARVLEAEAAATQKPAI"
     gene            complement(2008..2850)
                     /locus_tag="PC465_003444"
     CDS             complement(2008..2850)
                     /locus_tag="PC465_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015518395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2650717.1"
                     /translation="MKNEINAVLENMTATTPEPEDYTGEDGLLYCGKCRKPKEAYFAP
                     DKAAIFGRDRHPAECDCQRAAREEREAAEKRRRHLDTVEELKRRGFTDPTMRDWTFEN
                     DNGRNPQAGIARRYVEHWEDMRTDNIGCLFWGGVGTGKSYLAGCIANALMEKEIPVHM
                     TNFALILNDLAASFEGRNEYISRLCRYPLLILDDFGMERGTEYGLEQVFNVIDSRYRS
                     GKPLIVTTNLTLDDLRNPEDTAHSRIYDRLLSMCVPVRFTGENFRQETAQRKMESMKK
                     LITD"
     gene            complement(2847..3641)
                     /locus_tag="PC465_003445"
     CDS             complement(2847..3641)
                     /locus_tag="PC465_003445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006356266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HDF2650718.1"
                     /translation="MRDKLPKSTRTQGGDTIADYIMADTPLPLFLPYPRFLLKMEISQ
                     TAKLLYSLLLDRSTLSQKNKWQDDKGRIYIIYPIAEIAEILDKGSTTIKGALNELDAA
                     GLLERERGGFSAPNRLYVKVPRVPQVQFSDQLMAGNPTLTEPENRPTDGQKTDLMMVG
                     KPSPNQTTINNLTENQTKGVSGEPPAPYGRYQNIFLSQTEYNELQAEYPDRLERFIEE
                     MSRYLAASGKSYQNYAAALRIWAGNDKKGAPKKGIPDYSCKEGESL"
     gene            complement(3714..4100)
                     /locus_tag="PC465_003446"
     CDS             complement(3714..4100)
                     /locus_tag="PC465_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009259636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HDF2650719.1"
                     /translation="MSDKLPRMDYRQHRRARRLVHECCNYDEGNCLLLDDGEPCVCVQ
                     SISLSLMCRWFRVAVLPLDGELAAALLYRGSRKRCAVCGAAFVPKSNRGKYCPDCAGR
                     MKKIKAAERKRKQRHKCHALEPFKPA"
     gene            complement(4090..5706)
                     /locus_tag="PC465_003447"
     CDS             complement(4090..5706)
                     /locus_tag="PC465_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDF2650720.1"
                     /translation="MATLKHINSKNADYGAAEQYLLFEHDEFTMKPVLDETGRLIPRE
                     DYRLSTLNCGGEDFAVACMRANLRYEKNQRREDVKSHHYIISFDPRDGPDNGLTVDRA
                     QELGEKFCAEHFPGHQALVCTHPDGHNHSGNIHVHIVINSLRIEEVPFLPYMDRPADT
                     KAGCKHRCTDAALRYFKSEVMEMCHREGLYQIDLLNGSKNRVTDREYWAQKKGQAALD
                     KQNAPMIAGGITPRQTKFETNKEKLRQTIRAALSAATSFEDFSSLLLREGVAVKESRG
                     RLSYLTPDRTKPITARKLGDDFDRAAVLAVLEQNAARAAEKAAAIPEYQRHGKTGIQP
                     TKAPQTAPNVQRLVDIEQKKAEGKGRGYERWATMHNLKQMAATLNVYQEYGFTSPEQL
                     EAAVDTAYQDMRQTSGELKALETKLQGKKELQQQVLAYAKTKPARDGLKAQKSEKARA
                     AYRQANESDFIIAEAAARYFKAHGITKLPARKALQAEIEQLVSKKSGLYNTYHEQKQR
                     YTELQTVKRNIDQILRREEPRRRKEQSHER"
     gene            complement(5678..6076)
                     /gene="mobC"
                     /locus_tag="PC465_003448"
     CDS             complement(5678..6076)
                     /gene="mobC"
                     /locus_tag="PC465_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HDF2650721.1"
                     /translation="MPKRYNTPHRSRVVKTRLSEDEYADFTARLAPYGISQSEFLRQA
                     IRRTAIRPIIHVSAVNDELLSAVGKLTAEYGKIGGNLNQIARYLNEYGAPYNALSGEV
                     RAAIADLAALKYEVLQKVGDAVGNTQAYQL"
     gene            complement(6588..7022)
                     /locus_tag="PC465_003449"
     CDS             complement(6588..7022)
                     /locus_tag="PC465_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002605002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2650722.1"
                     /translation="MIKKAETNDLEILAKLAVMMWQNHSVSELINEFSEIMANGKSQF
                     FLKYENDIPIGFAQCQLRYDYVEGTSTSPVGYLEGIFVQEGYRNKGYAKELLAKCEAW
                     AKENGCHEFASDCEIDNMNSFHFHKAMNFTEANRIICFTKTL"
     gene            complement(7139..8047)
                     /locus_tag="PC465_003450"
                     /pseudo
     CDS             complement(7139..8047)
                     /locus_tag="PC465_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009248860.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(8044..8376)
                     /locus_tag="PC465_003451"
     CDS             complement(8044..8376)
                     /locus_tag="PC465_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009215075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2650723.1"
                     /translation="MARKYDHEYKVQAVKLAKEIGGAKAAKELGIPEGTIHTWLKAVR
                     AGKLDIGEGSHTPTSAMSLAEEITMLRKRVKEQDKEIRRLKEENEFLEEASAFFAASR
                     RKSAKTRE"
     gene            complement(8476..8673)
                     /locus_tag="PC465_003452"
     CDS             complement(8476..8673)
                     /locus_tag="PC465_003452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002571019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2650724.1"
                     /translation="MSKLLPYETIVKAHEGDPEAVDAVLAHYSRYIRYFSKINGQGNA
                     EVEDYVKQRLIASQFKFRFDR"
     gene            complement(8670..9089)
                     /locus_tag="PC465_003453"
     CDS             complement(8670..9089)
                     /locus_tag="PC465_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016281639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2650725.1"
                     /translation="MTEEEAYKVHIQYTFNAFCKVVIRHAAIDIILKLRRRWEREVSL
                     DYLMNEKFVQLAEPEQLEEYLFTACGQTAVLYHAELAAALALLPEQTQEEIFRYYFLR
                     QPQRVIGAHIGRSRSTAGRHIQLALQRLREEMEVRRP"
     gene            complement(9250..9651)
                     /locus_tag="PC465_003454"
     CDS             complement(9250..9651)
                     /locus_tag="PC465_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004079988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2650726.1"
                     /translation="MKFNEKLMSIRKAKGLSQEELGMELQVSRQTISKWESGQSYPDF
                     QRLVMLSDYFDMTLDELVKDIDVQDVRDKNLTDEKVASIYLDVENVKNKSRKFVKIFC
                     YAGVILLGIVILAFILHLFFPDIEWLWGSTQ"
BASE COUNT         1995 a         2593 c         2545 g         2731 t
ORIGIN      
        1 agaagtaata gaagtgtaaa aaattttgcc gttcctatcc ggcactcgcg cgttgtgtcg
       61 gataggtcgg gcgttaggtt tcgggcaagt caatcttgcc gacaaagctg taataaatct
      121 caatgtcctg cctgcgggtg ccgttctcgt catagctgca ctcatgcacg acgattttct
      181 caatcatttc ccgcaagagg gtgggggtaa gttcctcaaa ggcaaggtgc tttcggacga
      241 tacccataaa cttttccgcg ttgacggtgg cggcctgcga cttgtccagt tcctcctgca
      301 aagcggcggc gcggtctttc agttcccgct gttcctgctc atagtctgcc gacagttcca
      361 tgaaacgctc gtcgctgatt ttgccgttca cattgtcctc atacagccgc ttgataatgc
      421 ggctcacttc ggaaatgcgc tcctgcgcct gttcaagctg cttggtggct acggcggtct
      481 ttcttttgcc gccgatctcg ttctgctgga taagcagctt cacaaagcgg ctctcatgct
      541 tggcggcgta ttccgtcact tgccggagat tggagaggac accggcggtc aacaggtcgg
      601 tgcggataaa gtgcgccgta cagtcgcggg tgcgcttctt gtagctgccg cagatgtaac
      661 agtcctgctt gcgggttttg ttctgatacc gctgctggta catcacatgg ccgcagtcgg
      721 cgcagaacag cataccggag aacagcccca cttcatcgta gcggttcggg cgtttgcgct
      781 gcttgcgtaa ctcctgcacg cgctcccatg tttccgtgtc gataatcggc tcatggtggt
      841 tcgggaaaat ggcctgcttc tcgatggggt tctctatact gtgcttggtc ttgtaagaag
      901 gcttctccgt cttgaagttt accagacagc cggtgtactc acggttttcg aggatatgaa
      961 caacggtgtt cgtcgcccac ttgcactcat agccggggtg gtagcggcgg gtgctgcccg
     1021 tcctgcggta ttccagcgtc cccggcgtgg ggatttgctg ctccgtaagc atacgggcaa
     1081 tcttggtcgg gccgttcccg gcaaggcaaa gctggtatat ctgcttgact accggcgcgg
     1141 tttcctcgtc aacgatatag ttttcgtcct cgtccatgag gtagccatag accggcttgc
     1201 tggtaacggg cttgccgctc atgccttttg ctctcttaac tgccttgatt ttcttgctcg
     1261 tatctctcac cagccattcg ttgaacagat ttcgcagagg ggtaaaatcg ttgtccatgc
     1321 cgccgtttgc gctgtccaca ttgtcgttga cagcgataaa acgcacgccc ttttggggga
     1381 acagcatttc cgtgtaaaat cccacctgca agtagtttcg ccctaaccgg ctcatgtcct
     1441 tgacaatgac cgtacccact ttcccggctt caatgtctgc aagcatggct tgaaaaccgg
     1501 gcctttgaaa gttcgcgccg gaatagccgt cgtcggtgta ccagcgaagg ttggcaaagc
     1561 cattttgttt tgcaaaggtt tcgagtatcc ttttttggtt cgatatggaa ttactctcgc
     1621 cttgcaattc gtcctcatgg gacaatctcg gataaagggc ggtaatgagg ttttgggtgg
     1681 cttgtcttaa cataaaatcc tccgtttccg acagccagcc ccactattcc gtggtttcat
     1741 tgtaccacgg aacagggctg gttgtatagc ggcaaaagtg tcaaatctgc ttctttacag
     1801 cttgtcaaat cgccggtttt tgtgtagcag cggcttccgc ttccagtacc cgcgccattt
     1861 tgtcggcggc ggtggttgtg gtgtctttct tgaaatagcc ggacacgaca aggacggaat
     1921 tgcccatgcg gatttccgtc acgcagtcgg ggcggcgggc ggtgcgggtg tcgtgctgct
     1981 tgttatctgc cataggcaat actcctttca gtcggtaatc agtttcttca tgctctccat
     2041 tttccgctgc gcggtttcct gccggaaatt ctcgccagta aagcgtaccg ggacgcacat
     2101 ggaaagcagc cggtcataaa tccgggaatg ggcggtgtcc tccgggtttc gcaggtcatc
     2161 cagcgtgagg ttggtcgtga cgatcagcgg cttgccgctg cggtaacggc tgtcaatcac
     2221 attgaaaacc tgttccagcc catactcggt gccgcgctcc atgccgaagt cgtcaaggat
     2281 aagcagcgga tagcggcaaa ggcgggaaat gtattcgttc ctgccctcaa agctggcggc
     2341 aaggtcattg aggataaggg caaagttcgt catgtggacg gggatttctt tctccatgag
     2401 ggcgtttgcg atacagcctg caaggtagct tttcccggtt cccacgccgc cccagaacag
     2461 gcagccgata ttgtcggttc gcatatcctc ccaatgctcc acataccggc gggcaatccc
     2521 ggcctgcggg ttcctgccgt tgtcgttctc aaaagtccag tcccgcatgg tggggtcggt
     2581 aaagccccgg cgtttcagtt cttccacggt gtcaaggtgc ctgcgccgct tctcggcggc
     2641 ctcccgttcc tcgcgggcgg ctctctggca gtcgcactct gccgggtggc ggtcacggcc
     2701 aaagatagcg gccttatccg gcgcaaaata ggcttctttc ggtttgcggc acttgccgca
     2761 gtacagcaaa ccgtcctcgc cggtgtagtc ctccggctcc ggggtggtgg ccgtcatatt
     2821 ctccaaaaca gcgttgattt cgttcttcat aaactctcgc cctccttgca tgagtagtca
     2881 gggatgccct ttttcggggc gccctttttg tcgttccccg cccatatccg cagggcggcg
     2941 gcataattct ggtagctttt cccgctggcg gcaaggtagc ggctcatttc ctcgatgaac
     3001 cgttccagcc tgtcggggta ctctgcctgc aactcgttgt attcggtctg tgacagaaaa
     3061 atattctggt atcggccata gggcgcgggc ggctccccac tcactccctt tgtttggttc
     3121 tctgtaaggt tgtttatagt agtttggtta ggggacggtt ttccgaccat cataaggtcg
     3181 gttttctgac catcagtagg tcggttttcc ggctctgtga gggtcggatt tccggccatc
     3241 agttggtcgg aaaactgtac ttgtggcact cgaggtactt tgacatatag acggttcggt
     3301 gcggagaagc cgccccgttc ccgttccagc agccccgccg cgtccagttc attcagcgcc
     3361 ccctttatgg tggtgctgcc tttatccagt atttcggcta tctccgcgat gggatagata
     3421 atataaatcc tgcccttgtc gtcctgccac ttgtttttct gtgagagggt tgagcggtct
     3481 aacagaagcg aatacagcag cttggcggtc tgggaaatct ccattttcag caggaaacgg
     3541 ggataaggca gaaagagagg cagcggcgtg tctgccatga tataatcagc gatagtatca
     3601 cctccctgtg ttcgggttga ttttggcagt ttgtcacgca ttaggacggc gtttccggtg
     3661 gaaaaggata aatgtatcgc gcaccctttg acacccacga aaaaagcctt gatttatgcg
     3721 ggtttgaaag gctctaaagc gtgacattta tgcctttgtt tccgctttct ctcggcggcc
     3781 ttgattttct tcatgcgtcc ggcgcagtcg gggcagtatt tcccccggtt ggatttgggg
     3841 acaaaagccg ccccgcagac ggcgcagcgt tttcggctcc cccggtacaa gagggctgcg
     3901 gccagttccc cgtcaagggg caggacagcc acacggaacc agcggcacat gagggaaagg
     3961 gaaatgctct ggacgcatac gcaaggctcc ccgtcgtcta acagcaggca gttcccctcg
     4021 tcgtagttac agcactcatg caccagccgc cgcgcccgcc ggtgctggcg gtagtccatg
     4081 cggggcagct tatcgctcat ggctctgctc ctttctgcgg cggggttcct cccggcgcaa
     4141 aatctggtcg atattccgct tgacggtctg taactccgtg taccgctgct tctgttcgtg
     4201 gtaggtgtta tacaggccgg atttcttgga aacaagctgc tcgatctcgg cctgcaacgc
     4261 tttccgggcg ggcagcttgg taatgccatg cgccttgaaa taccgggcag cggcttcggc
     4321 tatgataaaa tcgctctcgt ttgcctgccg gtatgcggcg cgggctttct cggatttctg
     4381 cgctttcagc ccgtcgcggg cgggcttggt cttggcgtaa gcaagtacct gttgctgcaa
     4441 ctcctttttc ccttgtagct tcgtttccag tgctttcagt tcgccgctgg tctggcgcat
     4501 atcctgatag gcggtatcaa cggcggcttc taactgctcc ggggaagtga agccgtattc
     4561 ctgatacaca ttcagcgtcg cggccatttg tttgaggttg tgcatggtcg cccagcgttc
     4621 atagccccgg cctttgccct cggctttctt ctgctcaatg tccacaagcc gttgcacatt
     4681 cggcgcggtt tgaggggctt ttgtgggctg tatgccggtt ttcccatgcc gctggtattc
     4741 gggtatggct gcggcctttt ctgcggctct ggcggcgttc tgctccaaaa cggcaaggac
     4801 agcggcgcgg tcaaaatcgt cgcccagctt gcgggcggta atgggctttg tcctgtccgg
     4861 cgtgaggtaa ctaagccgcc cccggctctc cttgacggcc acgccctccc gcagcagcag
     4921 agaggaaaag tcctcgaatg aggtcgccgc agacagcgcg gcgcgtatgg tctgccgcag
     4981 cttctccttg ttcgtttcaa acttggtctg ccggggcgtg ataccgcctg caatcatggg
     5041 ggcgttctgc ttgtccagcg cggcctgtcc ctttttctgc gcccaatact cccggtctgt
     5101 gacgcggttc ttgctgccgt tcaagaggtc gatttggtaa agcccctccc ggtggcacat
     5161 ctccatgact tcggacttga agtagcgcaa ggccgcgtcg gtacagcggt gcttgcaacc
     5221 ggctttcgta tcggctggcc tgtccatgta gggcaggaac gggacttcct ctatccgcag
     5281 gctgttaatg acgatatgca catggatatt gccgctgtgg ttatggccgt ccgggtgggt
     5341 gcatacaagg gcctggtggc cggggaaatg ctcggcgcaa aacttctcgc ccaactcctg
     5401 cgcccggtct acggtcaaac cgttgtccgg gccgtcccgt gggtcaaagc tgatgatata
     5461 gtggtggctt ttcacatctt cccgccgctg gttcttctca tagcggagat ttgcccgcat
     5521 acaggcaacg gcaaaatcct ccccgccgca gttcagcgtg gacagccggt agtcctcgcg
     5581 ggggataagc ctgccggttt catcaaggac gggcttcatg gtaaactcgt catgctcaaa
     5641 cagcaggtac tgttcggcgg ctccgtagtc ggcgttttta gagttgatat gcttgagtgt
     5701 tgccaactgc gtcacctact ttctgtaaga cttcatactt gagggcggca aggtcggcta
     5761 tggcggcgcg tacctcgccg gacagcgcgt tgtagggtgc gccgtactcg ttcagatacc
     5821 gggctatctg attgaggttg ccgccgattt tgccgtactc ggctgtgagt ttcccgacag
     5881 cggaaagcag ctcgtcattg accgctgaca catggataat ggggcgtatg gcggtgcgcc
     5941 gtatcgcctg ccggagaaat tcggactggc tgataccata gggcgcaagc cgcgctgtga
     6001 agtcggcgta ttcatcttcg gacagccggg ttttcacaac gcggctgcgg tggggtgtgt
     6061 tgtatcgctt cggcatgggc tgtaaacctc ctttcactta tcacaaaaaa taggctggtc
     6121 tgttaggtat ttccggggca gttctcgcaa aaaagcggcc tgccggacgg aaatattttt
     6181 gcggcgcaag ccgccatagc agggtttggg gaaggcactc cccaacaagt ttcccgcgag
     6241 gggcaaaacc gcagaattgc ggattttggc accgtggtag aaacttgctc tttgtagctg
     6301 caatctccgg cgtatacggg ctttcttctt ttccgctaat ataacgcttg aaaagggctt
     6361 tgctgcccgc tgtacggggg aaaacggaag atttcttttt cctaccgttc cggcaagaga
     6421 aaaagggtat atttccccgt tcactctaaa taccaccgcc gttcccgttt tgacaaaaat
     6481 gggcgcaaaa aagcagtaaa tctttttcaa gacttactgc tcgttgtgcc gttgcggggc
     6541 ggcgggtatt tggttttcaa tgggaaatca gtcagatgaa ctgggcttta tagtgtctta
     6601 gtaaaacaga taattctatt tgcttctgta aaattcatag ccttatgaaa atggaaacta
     6661 ttcatattat ctatttcaca atcgctggca aactcatggc aaccgttttc tttcgcccat
     6721 gcttcgcact tggctaacaa ttctttggca tatcctttat tgcgataacc ttcttgcaca
     6781 aaaatcccct ctaaatatcc aaccggagag gtacttgtac cttccacata atcatatctt
     6841 aattgacatt gcgcaaaacc aataggtatg tcattttcat atttcaaaaa aaattgtgat
     6901 tttccattgg ccataatttc tgaaaattca ttgattagtt cactaacgga atggttctgc
     6961 cacatcatca cagctaattt tgcaagtatt tctaaatcgt tagtttccgc cttttttatc
     7021 atacatacgc tctcctttgc aaatttcact ttattgtttc atttgataac ttcattctac
     7081 catgcagcta tgatattgtc aagattagtt gacacatttt tctcaaggat atcactgact
     7141 atgcagccac ctccaaagcc tcatagtact gcctgcgttt taccatggga ggaaggccgc
     7201 cattggcaga gcagatcctc cggttgttcc agtagctgag aaagtatctc cagataagta
     7261 cctttagttc ttctacttcc atctgctttg tgtcataacg gtcataaaga agctccgtct
     7321 tcattctggc ccacatgctc tcgcagcgtg cattatcatg gcagcgccct ccggcactgt
     7381 tcatgctttg atggatatga tgctcccgga tggtctgacg gtaggactcg ctggtatact
     7441 gtgtcccacg gtcactgtgg atgatagcgc cttccaacgc aggataggca gtcagggcgt
     7501 tttccaatgt atggatacat agatcggctt tcatatttgt ttccattgcc agaccgagga
     7561 cactaagatc aaagcagtca aaaatcgcag atacatacag tttcccattg gatgccggaa
     7621 tctccgtgat atccgtaata catttttcta atggggtatc agaacggaaa tcccgtttta
     7681 gcagatcatc cgatttcatg gcttcacgat cagcctttgt gatcccgttg ggttttctct
     7741 taggtcgatg gctaaggcca atctgatcca taactcggta tacggttctc tcactgggaa
     7801 tatgcactcc ttccggctgt ttcagcaaca atgcctggta catccggatt cgaccataag
     7861 tatcgttaca ttcatcttca ctgacgattt ctttcatggc atctgccaaa tcctggtact
     7921 tccagggacg gtctttattt gcgagatatt tatagaagcc ttggcggctg accccaagca
     7981 ttctgcagta aaactagatt ttcccggtaa tcctgccgtc ttctgtcttc agggccagaa
     8041 agatcattct ctggtttttg ccgacttccg acggctggcg gcgaaaaaag cactggcttc
     8101 ctccaggaat tcgttttctt ccttcaggcg acggatttcc ttatcctgtt cctttacccg
     8161 tttgcgcagc atggtaattt cttctgccag gctcattgcg ctggtgggag tatgggagcc
     8221 ttctccgata tccagcttac cggctctaac agctttcagc caggtatgga tggttccttc
     8281 tgggattcct aattctttag cagccttagc gccgccgatt tccttggcaa gttttactgc
     8341 ctgtactttg tattcatggt catatttacg tgccactttg aatgcctcct tattctcttg
     8401 gttttattat gaaatccttg agaataagct gtcaactttt tttataccac accactatga
     8461 atttttctat gccagctatc ggtcaaaccg aaatttgaat tgactggcaa tgagccgctg
     8521 cttcacatag tcctccacct cggcattgcc ctgtccgttt atcttggaaa agtagcggat
     8581 atatctggag tagtgagcga gaacagcgtc caccgcctcg gggtcgccct catgtgcctt
     8641 gacgattgtt tcatagggga gaagtttact catggtcgcc gcacctccat ttcttcccgg
     8701 agccgctgca aggcaagctg gatatgccgc cccgctgtgc tgcgtgaccg gccaatgtgc
     8761 gcgccgatca ctcgctgcgg ctggcgcagg aaatagtaac ggaaaatttc ttcctgcgtc
     8821 tgctccggca agagggcaag ggcggcagca agttccgcat ggtacagaac agcggtctgg
     8881 ccgcaggcag taaaaagata ttcttcaagc tgctccggct cggcaagctg gacaaacttc
     8941 tcattcatca gatagtcaag ggaaacttcc cgttcccacc tccggcgcag cttcaagatt
     9001 atatctatgg cggcgtgacg aatgacaacc ttgcaaaagg cgttaaaggt gtactggata
     9061 tgcactttgt aggcttcttc ttcggtcatg gaaattcccc ctctctgata atagtgcggg
     9121 gcggcagcac tccttgctgt cgccccttga ttgcctatca gcaaaggcgg gcggggctgt
     9181 caacggcggc gcgtatgcgc cgtttatctt gaccgttgac tggctcggct ggctttgcta
     9241 aatgattcgt tattgagtac ttccccaaag ccattctatg tcggggaaaa acaaatgtag
     9301 aatgaaggcc aaaataacta ttcccaacaa tatgacacca gcataacaaa agatttttac
     9361 aaattttctg gacttgtttt ttacattttc gacatctaaa taaatagatg ccactttctc
     9421 atcagttaaa tttttatcgc gcacatcttg aacatcaatg tcttttacca actcatccaa
     9481 agtcatatca aagtagtcac tcaacataac taatctttga aaatccgggt aagattgtcc
     9541 agattcccat ttagaaatgg tttgccttga aacctgaagt tccattccca attcctcttg
     9601 cgataagcct ttcgcttttc taatggacat aagtttctca ttaaacttca cttgcaaaat
     9661 cctccttgcg tttgttgtat caagtatata gttttcgggt tttactggca agcaagaagt
     9721 gttggcaatt tgtcaattcg ctgtaacatc ttgaaattca agcgttttga aagcataggt
     9781 aaacctttca aaacatgagt gtagctattt gttgacacat atatttggaa taatgggctg
     9841 ctgtctatca aattcttgtg tgtt
//
LOCUS       DAMJXI010000105         9844 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.112, whole genome shotgun sequence.
ACCESSION   DAMJXI010000105 DAMJXI010000000
VERSION     DAMJXI010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9844
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.112"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            530..1438
                     /gene="trxB"
                     /locus_tag="PC465_003455"
     CDS             530..1438
                     /gene="trxB"
                     /locus_tag="PC465_003455"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDF2650727.1"
                     /translation="MVDIIVIGAGPAGLTSAIYAMRAGLSVTVFEKNIYGGQVASTSE
                     VENYPAVQKISGVEFSNNIYNQAVAQGVDIQFDEVEEINLEGKVKVVKTSSGEHKAKA
                     VILANGVERRKLGCAGEQEFTGRGVSYCATCDGAFFKDKEVAIVGGGNTALEDALFLA
                     NNCTKVYLIHRRDSFRGEEVLEKSVKARENIEILYSHGVEKIEGEKTVSKIEVKNLKT
                     EEKRTIDVSGIFIAIGLKPNNKMFENVLDLDEGGYIISDESCTTSVEGVYVAGDSRTK
                     FLRQIITAASDGAIAAVQAANYINVE"
     gene            complement(1528..3351)
                     /gene="typA"
                     /locus_tag="PC465_003456"
     CDS             complement(1528..3351)
                     /gene="typA"
                     /locus_tag="PC465_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HDF2650728.1"
                     /translation="MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCV
                     MDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVD
                     ASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
                     EFPIIYGIAKQGIAKLEMDDDSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDD
                     YVGRLGIGRIYKGTLKNNTQVAICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIV
                     VIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLK
                     DRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMH
                     KEDGKLMEPIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLL
                     GYRSEFINATRGEGTLVRSFEKFEEFKGEIPSRGNGVLIAQGPGVTMGYSLNALSDRA
                     VMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPPRIFTLE
                     EALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK"
     gene            3563..3805
                     /locus_tag="PC465_003457"
     CDS             3563..3805
                     /locus_tag="PC465_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650729.1"
                     /translation="MLEVTKIIIKYFASESDTFVKEEVCNFEELLKWSHKFIEGKKIE
                     DVLYIKSKENYKVNVIKSLEIKELEIVRKQQIPPYM"
     gene            3953..4144
                     /locus_tag="PC465_003458"
     CDS             3953..4144
                     /locus_tag="PC465_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HDF2650730.1"
                     /translation="MIRVCPNCSNVDVNKLKTLVGEENVKTGCIGQCRAFKKEAVGII
                     DNELEIKETEAEFFEACKE"
     gene            4428..6929
                     /locus_tag="PC465_003459"
     CDS             4428..6929
                     /locus_tag="PC465_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HDF2650731.1"
                     /translation="MSSNKVVESYKITGMTCAACAKAVERVTKKMDGVYDQSVNIATE
                     KLKIEYDNSKVNFDDIKQVVEKAGYGIIKEESNKKIDMKIDGMTCAACAKAVERVVKK
                     LDGVESISVNIATDKANIDYDPSKVKLSQIKAAIEKAGYKPIEEVRNKVDVDEDKLRK
                     EREMKSLFVKFIVAIVFAVPLFYIAMGPMIIKPIGPWPLPEIINPMTNTFNYALIQLI
                     LVIPVMIAGYKFYINGFKSLFSLSPNMDSLVAIGTLAAFLYSLYTTLQIANGQIQGMH
                     HHQLYYESAGIIIALILLGKYLESKSKGKTSEAIKKLMGLQPKTAIVLVDGKEVETPI
                     EEVEIGDILLVKPGTKIPVDGVVIEGYTSVDESMLTGESIPVEKNVGSKVTGASINKN
                     GVIKFKAEKIGGDTALAQIIKLVEDAQGTKAPIAKLADTVSGYFVPIVIAIAVVASLL
                     WFLIGGKDIVFVLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKGGEALES
                     AHKVNTVIFDKTGTITEGKPKVTDIVLNNNVKEEYLIKIASSAEKGSEHPLGEAIVKY
                     GEEKNIKFEKVDNFKAIPGAGIQVTINDESILLGNRKLMNDNNIKLGDLEEKSNILAS
                     QGKTPMYIAVDGNLSGIIAVADVVKESSKKAIEILHDMGIKVAMVTGDNAKTANAIAN
                     QVGIDMVLAEVLPEDKSKEVEKLQNQGKFVAMVGDGINDAPALAKADIGIAIGSGTDV
                     AIESADIVLMKSDLIDVPTAIKLSHETIKNIKQNLFWAFGYNTIGIPVAAGILYVFGG
                     PLLNPMIAAEAMSLSSVSVVSNALRLKNFKAYKRD"
     gene            7089..7757
                     /locus_tag="PC465_003460"
     CDS             7089..7757
                     /locus_tag="PC465_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2650732.1"
                     /translation="MNSSILVIEDDSNIQELISEFLSAEGYQVDTANDGLEGIQKFKQ
                     GSYDLVILDIMMPNLDGYGVCKMIRKSSSVPIIFLTALNDEGDQLKGFDLECDDYITK
                     PFSFNLLIKRVEAILRRSNKTINDKFIVFEKLKLDLNTYIAEIDGEPIELTLKEFNIL
                     KALIEKYPQVITREGLLDSIWGYDYYGDTRIVDAHIKNIRKKISLPYIKTVKGIGYTL
                     EKDI"
     gene            7741..9018
                     /locus_tag="PC465_003461"
     CDS             7741..9018
                     /locus_tag="PC465_003461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HDF2650733.1"
                     /translation="MRRIFDKWEKLSIKYKLFSITTSLLIALALIIYLILYFLLPSYY
                     HEYKIESLQESLKSLVDSSIHFDTYTLEERLYYMAKDQNLAILLKDNQGKIVYGKNEV
                     VILRYSKYMINSLEDEYRTSIPIYTKDAKDGPYTLELVMPLQPIDEANEVIRKLMPYI
                     ISIAILIAIIGAYIYSIVITKPLINIIESEREQEYRRKDFVATISHELKTPITIISGQ
                     IEGMIYSVGKYKDRDTYLKKSYECTQELKDLVNEMIEVSKSEILEKDLKLVSINISEL
                     LNRLVKRQVFLIEEKHMKTILKIEENLEIKADQERITKAINNIINNAIKYSPEESELI
                     IRLYDKNKRISKKTSNQRVVLEIENTGVTIEKRYLEEIFNPFYRIEKSRSRKTGGSGL
                     GLYIVSQIFKSHGFDYSIKNKENSVVFTVEFKN"
     gene            9419..9640
                     /locus_tag="PC465_003462"
     CDS             9419..9640
                     /locus_tag="PC465_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650734.1"
                     /translation="MDRLKRDMKNMKEDLKEGVKKTAYVMKNTAEDLKDDAQGAMVNL
                     EIKKDEMMERYEQKKFSKELEKQMKNEMK"
BASE COUNT         3922 a         1109 c         1665 g         3148 t
ORIGIN      
        1 ctttaatttg aaaaatgtaa ttatatggta tatcatataa atataagtaa atagtgctaa
       61 tatttaaact attaatcata attggttcaa caaaagtata tagttaataa tgtttaattt
      121 gaagaaattg ttagtgtgaa attacatata tattcaaatt aaattcataa atatttcaca
      181 taataatagt atactgtaaa caaaaggagg tattaaatat gggaatagta cttataacag
      241 cagcattagt tttggttatg tatggacttt caattctatc atatatatca gaaagcaata
      301 tattagaaga cactgtaaat gataaccaat aaggttttga attatataaa taagtgagaa
      361 ctgtaaataa aagttaattt ttatttgcag tttttttata tatatgtaaa ataaagttaa
      421 ttaataaaaa ataatgtttt gtttatagta tatatggata ataatagtaa agtataagaa
      481 tgatgagaat aatatataag aaataataat ataaagagag gtaaacgtta tggtagatat
      541 cattgtaatt ggtgctggac cagcaggttt aacttcagca atttatgcta tgagagcagg
      601 gttaagcgtt acagtatttg aaaaaaatat ttatggaggt caagttgcaa gtacctctga
      661 ggtagaaaat tatccagcag ttcaaaagat ttctggggta gaattttcta ataatatata
      721 caatcaagca gttgctcaag gtgttgatat tcagtttgat gaggttgaag agataaattt
      781 agagggaaaa gtaaaggttg taaaaacttc ttcaggtgaa cataaagcaa aggctgttat
      841 tcttgcaaat ggagttgaaa gacgtaaatt aggttgtgca ggggaacaag aatttacagg
      901 tagaggagta tcttactgtg caacatgtga tggagccttt tttaaagata aagaagttgc
      961 tatagtaggt ggaggaaata ctgcactaga agatgcttta tttttagcta ataattgtac
     1021 aaaagtgtat ttaattcaca gaagagatag ttttagaggt gaagaagtgt tggagaaatc
     1081 tgtgaaagca agagagaata ttgagatact ttacagtcat ggtgtagaaa aaatagaagg
     1141 agaaaagact gtatcgaaaa tagaagtaaa aaacttaaag actgaagaaa aaagaactat
     1201 agatgttagt ggtattttta ttgctatagg tcttaaacct aataataaaa tgtttgaaaa
     1261 tgttcttgat ttggatgaag gtggatatat aatttcagat gagtcttgta caacatcagt
     1321 agaaggtgta tatgtagcag gagatagtag aactaagttt ttacgtcaaa taataacagc
     1381 agcatcagat ggagctattg cagccgttca agcagctaat tatataaatg ttgaataata
     1441 taaatttcaa ataaaaatag ccatataaac tgaaataatt tttcagtact atatggctat
     1501 tttgttaatt agaggtaaat gtacgtttta tttaccttgt ctagatttgt tatatcttaa
     1561 tctatcatgt tcatttaaga atctttttct aagtcttata gaatcaggtg taatttcaac
     1621 taattcatca tcttctataa actctagtgc ttcttcaaga gtaaatattc taggaggaga
     1681 taattttata gcatcatctg aaccagaagc acgtacgtta ctcattttct tgtttttaca
     1741 agggttgact accatatcat cttttctgga attcatacca attatcatac cttcgtaaac
     1801 ttctacacca gggtctacaa acattacagc tctatcactt aaggcattaa gagaataccc
     1861 catagtaaca ccaggtcctt gtgctattaa aacaccattt cctcttgaag gtatttctcc
     1921 tttaaattct tcaaattttt caaatgaacg aactaaagta ccttctccac gagtagcgtt
     1981 tataaattca cttcgatatc ctaaaagacc acgagtaggt gctaagaact ctatttttac
     2041 atagtctcct tctattgaca tagattccat catacctttt ctcatgttta attcatttat
     2101 aatagtacca gagtaaactt caggacagtt tacaacaact ctttctattg gttccattag
     2161 ttttccatct tctttatgca ttaaaacttc aggtttagaa acaccaactt cataaccttc
     2221 acgtctcata ttttcaagta gtatagataa gtgaagctct ccacgtccag aaactttgta
     2281 tccatcagta gtatcaagag gttcaacttt aagaccaaca tttacttcaa gttccttttc
     2341 aagtctatct ttcaaatgtc tagttgtaac gaattttcca ctttttccaa cgaatggaga
     2401 gtcgtttact aagaagttca tagaaagagt aggctcttct atttttatca tttccatagg
     2461 tagtggacta tctaaatcgc atatagtttc acctatagat atatcaggaa taccagctat
     2521 aacaactatt tctccactag tagcttcatc aacttcaact tgttttaaac cttcatacac
     2581 agaaagtttt gatacttttc ctttagatac aacagaatct tctctacata tagcaacttg
     2641 tgtattgttt ttaagagtac ctttgtaaat tctacctata ccaagtctac ctacataatc
     2701 atcatatgca agagctgata tttggaactg tagaggttca ttatcgtaat taggataagc
     2761 ttcaacgtga tttacaatag ttttaaatag aggagaaagg tcttcactat catcatccat
     2821 ttcaagttta gcaatacctt gtttagcaat accatatatt ataggaaatt cgcattgctc
     2881 atctgttgca tttaagtcta caaataaatc gaaaacttca ttaactactt cttccgctct
     2941 ctggtctttt ttatcaatct tgtttataaa taatattggt tttaaaccga actctaaaga
     3001 tttttgtaaa acgaatctag tttgaggcat tgggccttca ctagcatcaa ctaatagaat
     3061 aactgtgtca acagttttca taacacgttc aacttcagaa gaaaagtcac tgtgtcctgg
     3121 agtatcaact atgtttattt tgtaatcttc atagtttatt gcacagtttt ttgaatatat
     3181 agttatgcct ctttcttttt caaggtcgtt actgtccata acgcagtctt taactacttc
     3241 gttctttcta aaaacaccgc tttgagaaag gaaagcatca accaatgttg attttccagc
     3301 gtcaacgtgg gctataactg cgatatttat aattttatgt ttttgtgaca tttttgttgc
     3361 tcccttcgat taaaataact tattaattat agcacaatat attattaggt acaaggagga
     3421 atatattaaa ttgtattaat atagtttaaa ttggataaaa ctgttagttt tgcatctgaa
     3481 aattattctg tttaaaaaaa ttttttagac aaataataac cttaatagat aaaaagatta
     3541 ataaaagagt aaaggatgat atatgttgga agtaaccaaa ataataatta aatattttgc
     3601 aagtgaaagt gatacttttg taaaagaaga agtttgtaat tttgaagaac ttcttaagtg
     3661 gtctcataaa tttattgaag gtaaaaagat agaagatgtt ttgtatataa agtctaaaga
     3721 aaactataaa gtaaatgtga ttaagtcttt agaaattaag gaattggaaa tagtgagaaa
     3781 acaacagata ccaccgtaca tgtagtatta ataatatata aaattaatat gtaatactcg
     3841 caataggata taaatggtat atatggtaat aatttatatt aaaaaaactt ttataaagtt
     3901 tatatttggg tataaaagta ttaattagac attaattagg aggaacttaa atatgataag
     3961 agtatgtcca aactgttcaa atgtggatgt aaataagcta aaaactttgg ttggagaaga
     4021 aaatgtaaag actggttgta taggtcagtg tagagcattt aaaaaagaag ctgttggaat
     4081 aatagacaat gagcttgaaa taaaggaaac agaagcagag ttttttgaag catgtaaaga
     4141 ataaatttta aataaaatat aataaataga gcatctaaat tgtataagta ttaaacaatt
     4201 tagatgctct atttttatat atacatttaa ttatgagtat acttttctat taaatacaaa
     4261 taaatataac taatacattt atttattaaa aaaatattga tttaatatac ctataggggg
     4321 tataataaaa atatagattt ctaaataagt aatttatcaa tattacatat caaaataaaa
     4381 cgttacaaat tagctgaaaa tatattgaaa gaaaggaaga ttttattatg agttcaaata
     4441 aagtggtaga aagttataaa attacaggta tgacatgtgc agcttgtgca aaggcagtag
     4501 agagagtaac taagaagatg gatggagtat atgaccaaag tgtaaatata gctactgaaa
     4561 aacttaaaat agaatatgat aattctaagg ttaattttga tgatataaag caggttgtag
     4621 aaaaagcagg atatggaatt ataaaggaag aaagtaataa aaaaattgat atgaaaattg
     4681 atggaatgac atgtgcagct tgtgcaaaag ctgtagagag agtggtaaaa aaattggatg
     4741 gagtagaaag tattagtgtg aatattgcaa cagataaagc taatatagac tatgacccat
     4801 caaaagtaaa attatctcaa ataaaagcag ctattgaaaa agctggatat aaaccaatag
     4861 aagaggtaag aaataaggtt gatgtggatg aagataaatt gagaaaagaa agagaaatga
     4921 agtctttatt tgttaaattt atagttgcaa tagtatttgc agtacctctg ttttatatag
     4981 caatgggacc tatgataata aagcctatag ggccatggcc tttgccagaa attataaatc
     5041 ctatgacaaa tacttttaat tatgcattaa ttcagttaat tttagtaata ccagtaatga
     5101 tagctggtta taaattttat ataaatgggt ttaaatcact tttttcttta agccctaata
     5161 tggattcttt agttgcaata ggaacattag ccgcattttt atatagtcta tatacgacac
     5221 tacaaatagc caatggacaa attcaaggta tgcaccatca tcagttgtat tatgaaagtg
     5281 caggaataat aatagcactt atcttacttg gtaaatattt agaatcaaaa tcaaaaggaa
     5341 aaacatcaga agcaattaaa aagcttatgg ggctacaacc taaaactgca atagtgttag
     5401 ttgatggtaa agaagttgaa actcctatag aagaagtaga gataggagat atactattag
     5461 taaaaccagg aactaaaata cccgtggatg gagttgtaat agaaggatat acatcagttg
     5521 atgaatcaat gcttacaggt gaaagtatac cagtagaaaa gaatgttgga agtaaggtga
     5581 caggagctag tattaataaa aatggtgtta ttaagtttaa ggctgaaaaa attggtggag
     5641 atactgctct tgcccaaata ataaagttag ttgaagatgc acaaggtaca aaagcaccta
     5701 ttgctaaact tgccgatact gtatctggat attttgtacc aatagtaatt gcaatagctg
     5761 tagttgcatc attattgtgg tttttaatag gaggaaaaga tatagtattt gtacttacta
     5821 tatttatatc agtacttgta attgcttgtc cttgtgcatt aggattagca acaccaactg
     5881 ctataatggt tgggactgga aagggcgcag aaaatggaat cttgataaaa ggtggagagg
     5941 cactagaatc tgcacataaa gtaaatacag tgatatttga taaaacaggt actataacag
     6001 aaggaaagcc aaaagtaaca gatatagtat taaataataa tgtaaaagaa gaatatctta
     6061 tcaagattgc ttcaagtgca gaaaaaggtt cagagcatcc tcttggagaa gcaatagtta
     6121 agtatggaga agagaagaat ataaaatttg aaaaagttga taattttaaa gccataccag
     6181 gtgctggtat acaagttact attaatgatg aaagtatatt acttggaaat agaaagctta
     6241 tgaatgacaa taatataaag cttggggatt tagaagaaaa atcaaatata ttggcaagcc
     6301 aaggtaaaac acctatgtat atagctgtag atggaaattt atcaggtata atagcagttg
     6361 cagatgtagt caaagaaagt agtaaaaaag caatagaaat acttcatgat atgggaataa
     6421 aagttgcaat ggtaactgga gataatgcga aaactgcaaa tgctatagca aatcaagtag
     6481 gtatagatat ggttttggca gaggttttac cagaagataa gtcaaaagaa gttgaaaaac
     6541 tacaaaatca aggaaagttt gttgcaatgg taggggatgg aataaatgat gccccagctc
     6601 ttgcaaaagc agatataggg atagcaatag gaagtggaac ggatgtagcc attgaatctg
     6661 cggatatagt acttatgaag agtgatttaa ttgatgttcc aacagcaatt aaacttagtc
     6721 atgaaactat aaaaaatata aaacaaaacc tattttgggc atttggatat aatacaattg
     6781 gtatacctgt agcagcagga atattatatg tatttggagg acctttatta aacccaatga
     6841 ttgcagcaga agcaatgagc ttaagttcag tttcagtcgt atcaaatgca cttagactta
     6901 aaaacttcaa ggcatataag agagattaga ttaataaatt aaataaaatg tatccaaaag
     6961 agctatcttt aaattaaaag gattaattta caaattaaga tagctctttt ttcatgtaaa
     7021 attcacaaca ataagataaa atataagtaa tatacgaaat tttaaataaa atagaaagga
     7081 ttgatagaat gaattcgtca atacttgtaa ttgaagatga ttcaaatata caagagttaa
     7141 tatcagaatt tttaagtgca gaaggttatc aagttgatac agcaaatgat gggttggaag
     7201 gtatacaaaa gtttaagcaa ggaagttatg atttagtcat attagatata atgatgccaa
     7261 acttagatgg ttatggagtt tgtaaaatga taagaaagtc atcgagcgtt ccaattatat
     7321 ttttaactgc tttaaatgat gaaggagacc aacttaaagg gtttgactta gaatgtgatg
     7381 attatataac aaaaccattt tcatttaatc ttcttataaa aagagtagaa gcaattttaa
     7441 ggcgaagtaa caagactata aatgacaaat ttatagtttt tgaaaaatta aaattagatt
     7501 taaacacata tattgcagag atagatggag aacctataga acttacacta aaagagttta
     7561 atatattaaa agctttgata gaaaagtatc cacaagttat aactagggaa ggtcttttgg
     7621 atagtatatg gggttatgac tattatggag atactaggat tgttgatgca catataaaaa
     7681 atataagaaa aaaaatatca ttaccatata ttaaaactgt aaaaggaata ggatatacac
     7741 ttgagaagga tatttgataa gtgggaaaag ttaagtataa agtataagtt attttcaata
     7801 acgacatcat tattaatagc attagcttta ataatatatc taattttata ttttttattg
     7861 ccatcatatt atcatgagta taaaattgag tctcttcaag aaagtttgaa atctttagta
     7921 gatagttcaa ttcatttcga tacatatact ttagaagaaa gactttatta tatggctaaa
     7981 gaccaaaatt tggctatttt attaaaagat aaccaaggta aaattgtata tggtaagaat
     8041 gaagtagtta ttttaagata tagtaagtac atgattaata gtcttgagga tgagtataga
     8101 acttctatac ctatatatac taaagatgca aaagatggtc catatacttt agaactcgtt
     8161 atgccattac aaccaattga cgaagcaaac gaagttataa gaaaactaat gccatacatc
     8221 atatcaatag caatattgat agcgattatt ggagcatata tatattcaat tgtaataaca
     8281 aagcctctta taaacataat agagagtgag agagaacagg aatatagaag gaaggatttt
     8341 gttgctacaa tatcacatga actaaaaact ccaataacca taataagtgg tcaaattgaa
     8401 ggtatgattt atagtgtagg taagtataag gatagggata cttatctgaa aaaatcgtat
     8461 gagtgtacac aagaattaaa agatttagta aatgaaatga tagaggtttc aaaatcagaa
     8521 atacttgaaa aagatttgaa attggtatca ataaatataa gtgaattatt aaatagactt
     8581 gtaaagagac aagtattttt aatagaagaa aaacatatga aaactatttt aaaaatagaa
     8641 gaaaatttgg aaattaaggc agaccaagag agaataacta aggcaatcaa taatataata
     8701 aataatgcca taaaatattc tcctgaagaa tcagagctta taattagact ctatgataaa
     8761 aataaacgaa taagtaaaaa gacttctaat caaagagtgg ttttagaaat tgaaaatact
     8821 ggtgtaacta tcgagaaacg ttatttagaa gaaatattta atccatttta tagaatagaa
     8881 aaatctcgtt caagaaaaac tggaggaagt ggacttggac tttatatagt cagccaaatt
     8941 tttaaaagtc atgggtttga ttatagcata aaaaacaaag aaaactctgt agtattcaca
     9001 gtagaattta aaaattaatt acttattata aagaatatat aactttcaat aatagttcat
     9061 tttaaaatca caaaaaattc ataatgaaac tgtattatat aaatataaag aagcttaaaa
     9121 ccataaaata caccaactat aatgatgaga tttccttaca tcctccatat aagtcatcat
     9181 tatagtaacc caacaattaa gttactatga atttaaaaaa taacaccgag catataatct
     9241 atgcttagtg ttatttttat tttgaaataa aaaatattta atttattgaa atgtatagat
     9301 ttagatagtt taaactatat ttaagactta aaaattataa ttgatattac aaataaatat
     9361 atgtactttg ggaaaaataa atataggaag tattatattt acagaggagg tagttttgat
     9421 ggatagatta aaaagagata tgaaaaatat gaaagaagat ttaaaagaag gtgttaaaaa
     9481 gacagcttat gttatgaaaa atacagctga agatttgaaa gatgatgcac aaggtgctat
     9541 ggtaaactta gaaataaaaa aagatgaaat gatggaaaga tatgaacaaa agaaattttc
     9601 taaagaatta gagaagcaaa tgaagaatga aatgaaataa gcttttattt atgaataaca
     9661 aattattgta ttcatataaa aagtagccag taatattaaa tagtttattt aaggaaatag
     9721 actttctaaa aataactgta ttagatttag aaagtctatt tcaaattagt tttataaata
     9781 gacataagga taaagtagat gttatagaac tagattttaa aaaatagata ctaaggataa
     9841 aata
//
LOCUS       DAMJXI010000106         9530 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.113, whole genome shotgun sequence.
ACCESSION   DAMJXI010000106 DAMJXI010000000
VERSION     DAMJXI010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9530
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.113"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            113..1873
                     /gene="prdR"
                     /locus_tag="PC465_003463"
     CDS             113..1873
                     /gene="prdR"
                     /locus_tag="PC465_003463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator
                     PrdR"
                     /protein_id="HDF2650735.1"
                     /translation="MFSIPEVKKVEEVMDTKFTTIDEDTRIEDAIKEMIKSNTKTLMV
                     IDSSDQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILK
                     NIGILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVI
                     LWNKFMEERYDIKSEDIVGRPMNEFLENTISEKVLNSKVGMSDLYFTDKKENMYALVH
                     ANPIFYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGK
                     SYKLEKSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPN
                     ELFESEFFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEK
                     EIRRVGGDTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKED
                     IGLLVHSFLEEICKQNNKPVLTISKDVIDIFQNYRWKGNIRELKNTIENIVVLSQNSK
                     IDVDDVPSYMMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILN
                     IPRTTLYYKIDQYKIDVSKI"
     gene            2302..4182
                     /gene="prdA"
                     /locus_tag="PC465_003464"
     CDS             2302..4182
                     /gene="prdA"
                     /locus_tag="PC465_003464"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="HDF2650736.1"
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLED
                     SGLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAP
                     VSEAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAA
                     EVAPKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVV
                     DMKLEIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQI
                     GEFGSSEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQ
                     EIREALKKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLG
                     AQPNVDLGNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDL
                     VGVVFVGSPQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMR
                     GIPVVGVSFSAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAML
                     KNAIEGVEVKAPERKWNPNVKLNNIEAIEKFTGEKIVLEENEQSLPMSKKRREIYEKD
                     EN"
     gene            4263..4547
                     /locus_tag="PC465_003465"
     CDS             4263..4547
                     /locus_tag="PC465_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650737.1"
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLI
                     TDYELKIGQEVGFMLSYPEVLSPEPNQEYVENIRREKEKQAEMQSKQEEK"
     gene            4585..5310
                     /gene="prdB"
                     /locus_tag="PC465_003466"
     CDS             4585..5310
                     /gene="prdB"
                     /locus_tag="PC465_003466"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:5035..5037,aa:Sec)
                     /transl_table=11
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="HDF2650738.1"
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVH
                     LKSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAE
                     GFIKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAGUGTCHRTAVI
                     VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPHNIEMQTHILRDTL
                     EQLVAIPSAGKIVPLPYEYKAHV"
     gene            5390..6148
                     /gene="prdD"
                     /locus_tag="PC465_003467"
     CDS             5390..6148
                     /gene="prdD"
                     /locus_tag="PC465_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="HDF2650739.1"
                     /translation="MEEKIMRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKE
                     REELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGAD
                     EDGNQMHEFGSSEGILKDQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRA
                     CDDFIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKE
                     PSGFEGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     gene            6163..6630
                     /locus_tag="PC465_003468"
     CDS             6163..6630
                     /locus_tag="PC465_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HDF2650740.1"
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNE
                     NKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQ
                     AKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     gene            6648..7130
                     /locus_tag="PC465_003469"
     CDS             6648..7130
                     /locus_tag="PC465_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HDF2650741.1"
                     /translation="MSFVGISTSMKNTSLHIFRDPLLDLIDNDSDIDLLGVVVVGTSE
                     HNEWKTFLATRLGRWIESLRPDGVIITLDMAGNQHIDFTNAIAEFVKSDIPTVGLTIM
                     GADGLVITNPYLDKATIIDYKKTTGYIETEVVGDNHMDEVDVKKALAFLKLKMRKDAK
                     "
     gene            7150..8157
                     /locus_tag="PC465_003470"
     CDS             7150..8157
                     /locus_tag="PC465_003470"
                     /EC_number="5.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="HDF2650742.1"
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEEN
                     LDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAA
                     IETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPG
                     VGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLA
                     HIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGE
                     KFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFIL
                     K"
     gene            8277..9158
                     /locus_tag="PC465_003471"
     CDS             8277..9158
                     /locus_tag="PC465_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HDF2650743.1"
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVT
                     GFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIP
                     VDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWINVLP
                     GGGNELGLTGVKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGS
                     CALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIA
                     YTSATMIMAANKNKKTA"
BASE COUNT         3754 a         1161 c         1881 g         2734 t
ORIGIN      
        1 aattacttaa taaattttaa taataattat ttaataaata attattataa tatgctagaa
       61 taaatatata taaataagtt ttgatgaggt actactataa aggggggact ttatgttttc
      121 gataccagaa gtaaaaaaag tagaagaggt aatggataca aaatttacaa ctatagacga
      181 agacacaaga attgaagatg caataaaaga aatgataaaa agcaacacaa aaactctaat
      241 ggtaatagat tcatctgacc aattaaaagg cattatatcc atgacggata tacataatct
      301 ttatgagatg cataaaaagt atgaaggtca accagtaaaa cttataatga agaaggatgt
      361 aatatatgtc aacgaaggtt taaccttaga tgaatgtaga gatataatga tattaaaaaa
      421 tatagggatt cttcctgttc ttagagataa taaaattatt ggagttctaa aacaagagca
      481 cattagggac tatctatata tgcatttaga agattatgga ttaactttga agtatattat
      541 aggtcaaatt aaagaaggaa tttgtgctat aaataacgaa ggtgttgtta tcttgtggaa
      601 taagtttatg gaggaaaggt atgatataaa gtctgaagat atagttggtc gaccgatgaa
      661 tgaatttttg gaaaatacta tttcagaaaa agtactaaat agtaaagttg gaatgagtga
      721 cttgtatttt acagataaaa aagaaaatat gtatgcatta gttcatgcaa atcctatatt
      781 ttataaagaa gaatttatcg gtgttgtatg tacagaagtt gatgttacag aagctaagat
      841 attagctctt gaacttgaaa aagtaaatga tacattaaaa tatctaaaga acgaagtcaa
      901 aaatttatct aaaggtagtt ttgataagat tttaggtaaa agttataaat tggaaaaatc
      961 gaaagcgatt gcaaaacaag tggctagaac aaatagtagc atatttattt ggggcgaaag
     1021 tggtacaggt aaagaagtat ttgcaagagc tattcatgat tatagtgaga gaaaaggtca
     1081 atttatacct gttaactgta gtgccatacc aaatgagtta tttgaaagtg agttttttgg
     1141 gtatgaatca ggtgcgttta caggagcaag taaaaagggt cgaataggta tatttgaact
     1201 tgcaaaagat ggaactgtat ttttagatga aattgccgat ttacctctta gtatgcaagc
     1261 aaagttgctt agagtattac aggaaaaaga aataagaaga gttggtggag ataccacaat
     1321 aaaaataaat cctagaataa tatcagctac caataaagat ttgagtaaaa tggtaaaggc
     1381 agaaaaattt agagaagatt tatactatag attaaatgtt gttgaaataa agattcctcc
     1441 acttagagag agaaaagaag acataggatt attggttcat agctttttag aggagatatg
     1501 taaacaaaat aataagcctg ttcttacaat tagcaaagat gtaatagata tatttcagaa
     1561 ttatagatgg aaaggtaata ttagagaatt aaaaaatacg attgaaaata ttgttgtatt
     1621 gtcacaaaat tctaaaatag atgtggatga tgtaccaagt tatatgatgg attctacaaa
     1681 taatagtact gaagaagaag agtatccttt agatttaacg aaggcaactc aaaaaattga
     1741 aataaagaat ataaccaagg cacttaaaat gtctaatgga aataaagcta aagcagctaa
     1801 gatattaaat atacccagaa caactttgta ttataagata gaccaataca aaatagatgt
     1861 gtctaaaata tgacacatga ctaaattttg acaaaatgat aaactttaat ttaaaaccta
     1921 gtaaagccaa cgcttgtata agtgttgtgt atatagatgt gttaaaaaaa atgaaaaagt
     1981 gttgattaat tgacactttt tttgtttgag aaaatgttta caaatacaaa aaataacata
     2041 ttttaaataa atatttatat aatatttggc taaaaatagc gatagatgaa gaatctatta
     2101 tagaaaaaat ctttttgtta ataagttggc ataggaattg cttataatat aaagtgactt
     2161 taagtgagaa aaaaataata ttaatcataa caaattatgt aggttttaat ttacttaatt
     2221 tctcagttaa ggggttacct gttgaggaat tgagatttaa aataataaat aagaaaataa
     2281 tgtaaggagg tattttatac tatgtcaata actttagaaa cagctcaagc ccatgcaaat
     2341 gacccagcag tttgttgttg tagatttgaa gcgggaacaa ttatagcgcc agaaaactta
     2401 gaagatccag caatatttgc agacttagag gattctggat tattaacaat accagaaaat
     2461 ggattaacta taggtcaagt actaggagct aagttaaaag aaactttaga tgcactttct
     2521 ccaatgacta cagataacgt agaaggatac aaagcaggag aggctaaaga agaagtagta
     2581 gaagaaacag tagaagaagc agctccagta tcagaagcag cagtagttcc agtaagcaca
     2641 ggagttgcag gtgaaacagt taaaatacac ataggtgaag gtaagaacat aagcttagag
     2701 atacctttat cagtagctgg tcaagcagga gttgctgctc cagtagcaaa cgttgctgct
     2761 ccagtggcaa gtgcagcagc agaagtagct ccaaaagttg aagaaaagaa acttttaaga
     2821 agcttaacta aaaaacactt taaaatagat aaagttgaat ttgctgatga aactaaaata
     2881 gaaggaacta ctttatacat cagaaacgca gaagaaatat gtaaagaagc taatgaaact
     2941 caagagttag ttgtagatat gaagttagaa ataataactc ctgataaata tgaaacttac
     3001 agtgaagctg tattagatat acaaccaatc gctactaaag aagaaggcga attaggttca
     3061 ggtataacta gagttataga tggagctgta atggtattaa ctggtacaga tgaagatgga
     3121 gttcaaatag gtgaatttgg ttcttcagaa ggtgagttaa atactactat aatgtggggt
     3181 agaccaggtg ctgctgacaa aggtgaaata ttcatcaaag gtcaagtaac aataaaagca
     3241 ggaactaaca tggaaagacc aggaccttta gctgctcacc gtgcatttga ctatgtaact
     3301 caagaaataa gagaagcatt aaagaaagtt gacaactctt tagtagttga tgaagaagta
     3361 atagagcaat acagaagaga aggtaaaaag aaagttgttg ttataaaaga aataatggga
     3421 caaggtgcaa tgcatgataa cctaatatta ccagttgagc cagttggtac attaggagct
     3481 caaccaaacg ttgacttagg aaacatgcca gttgtattat ctccacttga agtattagat
     3541 ggtggtatcc atgcattaac ttgtatagga cctgcatcaa aagaaatgtc aagacattac
     3601 tggagagagc cattagtaat aagagctatg gaagacgaag aaatagattt agtaggtgtt
     3661 gtatttgttg gttctccaca agtaaatgct gagaaattct atgtatctaa gagattaggt
     3721 atgttagttg aagctatgga agttgatgga gctgtagtaa ctactgaagg tttcggaaac
     3781 aaccatatag atttcgcatc tcacatagag caaataggta tgagaggtat accagtagtt
     3841 ggtgtaagtt tctcagctgt tcaaggtgct ctagttgttg gtaataaata catgactcac
     3901 atggtagaca acaataagtc taagcaaggt atagagaatg aaatattatc taacaacact
     3961 ttagctccag aagatgctgt tagaataatg gctatgctta aaaatgctat agaaggtgta
     4021 gaagttaaag ctcctgaaag aaaatggaat ccaaatgtta aattaaataa catagaagct
     4081 atagaaaaat ttacaggaga aaaaatagta ttagaagaga atgagcaatc tctaccaatg
     4141 agtaagaaga gaagagaaat atacgaaaaa gacgaaaact aaaatttaga tactaactaa
     4201 gatttagaca ataacataaa tttagatcca agtttaaaac agtatagaga ggtagaatta
     4261 taatggatag gttaaaatat atctcatcag agacttttta tgaaggtatt atagttgaca
     4321 tcaaaggtgg tggagtgact atagacctaa aaggtagact tggacaattt aaaataccta
     4381 atagaatgct tataactgac tacgaactta agataggtca agaagttgga ttcatgctaa
     4441 gctatcctga ggtattaagt ccagagccta atcaagagta tgtagaaaat attaggagag
     4501 aaaaagaaaa acaagcagaa atgcaatcaa aacaagaaga aaaataataa ataatcgttt
     4561 gaaaatagaa gggagaggaa atatatgagc cttacaacag tacaaggact tcaatctgaa
     4621 atattcgttc caataacacc tcctccagtt tggactcctg taactaaaga attaaaagat
     4681 atgactatag ctttagctac agcagctggt gttcatttaa aatctgacaa gagatttaat
     4741 ctagcaggag atactacatt tagagctata cctaatacag ctacagttga tgaaatgatg
     4801 gtatcacatg gtggatatga caatggagat gtaaacaaag atataaactg tatgttccct
     4861 atagatagat tacatgaatt agctgcagaa ggatttatca aaggagtagc tcctatgcac
     4921 tatgcattca tgggtggtgg aggaaaccaa catgtcttca ctgaagaaac tggtcctgct
     4981 atcgctgcta aacttaagga agagggagta gacggtgtag ttatgacagc tggctgaggt
     5041 acttgccata gaactgccgt gatcgtgcag agagcaatag aggaagctgg aatacctaca
     5101 ataataatag cagctcttcc tccagtagtt agacaaaacg gaactcctag agcagttgct
     5161 ccattagttc caatgggtgc taatgctggt gaaccacata atatagaaat gcaaacacat
     5221 atattaagag atacattaga gcaattagtt gcaataccat ctgctggtaa gatagttcca
     5281 ttaccatacg aatataaagc tcacgtttaa aatgtaattt atatttgaaa atatagaacc
     5341 cttctcctac acggttagga gaggggtttt aagaacaaag gtggatatta tggaagaaaa
     5401 aataatgaga agacttgtta taaaaccgtt tcatatgaat gaagttaatt tcggttcaaa
     5461 aacttctata aagaaagatg tacttacaat agatttatca agtatagatg aaataaaaga
     5521 aagagaagag ttaataacag acataaaagt agacattata aaacctggag attatgacag
     5581 agaaattaat actattatgg acattatacc aatatcaaca aaagttttag gcagactggg
     5641 agagggtatt acacatactt taacgggtgt atatgtaatg ttaactggtg cagatgaaga
     5701 tggaaatcaa atgcatgaat ttggttcttc agaaggaatt ttgaaagacc aaatggtatt
     5761 tgggagatat ggaactccat cagttgaaga ttatataatc catgtagatg taactttaaa
     5821 gggaggttta ccttttgaaa gaacacttcc acttgcagca ttcagagcat gtgatgattt
     5881 tatacaagaa ataagagcgt ctttgaaaat ggaagacgga agaaatgcta ctcaagttcg
     5941 tgaatatttt gacaaaattc gaccaaatgc aaaaaaggtt gtcatagtaa aacaaatagc
     6001 aggtcaaggt gctatgtatg acaatcagtt attctcaaag gaacctagtg gatttgaagg
     6061 aggaacatca attatagata tgggaaatgt acctatgatt atatctccta acgaatacag
     6121 agatggtgcc cttagagcta tgacttaaga gaggtggata ttatgggaat aggaccttca
     6181 acaaaagaaa catctcttca tcactttaga gacccacttt tagacatagt tgaaagtgat
     6241 aaggatgtag atttacttgg agtaatagta gtaggaactc cagatggaaa tgaaaataaa
     6301 acctttgtgg gacaaagaac ggccgcttgg ctggaagcca tgagagtaga tggagctata
     6361 gtttcatcag atggttgggg aaactcacat gttgactacg ctaacacatt tgaggaaata
     6421 ggaaaaagag atatacctgt agttggagtt acatttaatg ggactcaagc taagtttgtt
     6481 gtaagcaatc aatatatgga taccatagtt gatatgaaca aatcaaaaga aggtattgag
     6541 acagaagtag ttggagaaaa caacacaaat gaaatagatg ctaaaaaagc tttggcattt
     6601 ttaaaactta aaatgagaaa acatggataa aaaatttaag taagggaatg agttttgtgg
     6661 gaatttctac atcaatgaaa aacacatcac ttcatatatt tagagacccg ttactagatt
     6721 tgatagataa tgattctgac atagacttgt taggagtggt tgtagttggg acatcagagc
     6781 acaatgaatg gaaaacattt ttagcaacta gacttggaag atggattgaa tcattgcgac
     6841 ctgatggagt gattataact ttagatatgg caggaaacca acatattgat tttacaaatg
     6901 ctatagcaga gtttgtaaaa tcagatatac ctacagtagg tcttactatt atgggagcag
     6961 atggattagt aattaccaat ccatatttgg ataaagctac cataattgat tataaaaaga
     7021 caacaggcta catagaaaca gaagtagttg gagacaatca catggatgaa gttgatgtta
     7081 aaaaagcatt ggctttccta aaattaaaaa tgcgtaaaga cgcaaaataa acctaagggg
     7141 gaatttgata tgaaatttag cagaagtata caagctatag actctcatac agcaggtgaa
     7201 gcaactagaa tagttgtagg tggaatacct aacataaaag gaaattctat gcctgagaaa
     7261 aaagaatatt tagaggaaaa tctagattat ttaagaactg ctataatgtt agagccaaga
     7321 ggacataatg atatgtttgg ttctgtaatg actcaacctt gttgcccaga tgctgacttt
     7381 ggaataatct tcatggatgg tggcggatac cttaacatgt gtggccatgg tacaatagga
     7441 gctatgacag cagctataga aacaggtgta gttccagcag tagagcctgt aactcatgta
     7501 gttatggaag ctccagcagg aataataaga ggagacgtta cagttgtaga tggaaaagct
     7561 aaagaagtat cattcttaaa cgtaccagct ttcttatata aagaaggtgt tgaagttgac
     7621 ttaccaggtg ttggaactgt taaatttgac atatcatttg gtggaagctt ctttgctata
     7681 atacatgcaa gtcaattagg tttaaaaatc gaacctcaaa atgctggtaa attaactgaa
     7741 ctagctatga aacttagaga tataataaat gagaaaatag aaatacaaca tccaacttta
     7801 gctcatataa aaactgtaga cttagttgaa atatatgatg agccaactca tccagaagct
     7861 acttacaaaa atgtagttat atttggtcaa ggtcaagttg acagatctcc atgtggaact
     7921 ggaacaagtg ctaaattagc tactttacat gctaaaggtg aattaaaagt aggagaaaaa
     7981 ttcgtatatg aaagtatatt aggaacttta ttcaaaggtg aaatagttga agaaactaaa
     8041 gttgcagatt tcaatgctgt agtacctaaa ataactggtt ctgcttatat aactggattt
     8101 aatcattttg taatagatga agaagaccca cttaaacatg gatttattct taaataagta
     8161 ataaataaat taggaaatta aaatagaata gtagccactt gtcggttgct attctatagc
     8221 ttttaggcta taagattcag aatatatgaa aaaataaaaa aataggagga tggattatgg
     8281 tagcaatctt aaaggcatta tatgtagtat tcgcagcaat ctttgcagtt gtgtttggta
     8341 aagacgtagc taaagcaaac aaagagggga aactagaaga acaaagtact ccaaaagttg
     8401 ctgtaacagg atttataaca gacttctttg atacattagg aatagggtca tttgctccaa
     8461 caatagcaat gtcaaaggct ttaaagttaa atataccaga taaaaaaatg cctggtacat
     8521 taaacgtagc acatactatt ccagttgtta cagaagcatt catatttaca tcaatcatac
     8581 cagttgatgg tgttacttta gtatctatgg ttgtagcagc agcagttggt tcatatatag
     8641 gtgcaggaat aatagctaag atggacgaga gaaaaataca acttgttatg ggtgtaactt
     8701 tagcattaac agcaatatta atgttattag gtcatccttg gattaacgta ttaccaggtg
     8761 gaggaaatga attaggtctt actggtgtta aattagtaat aggtgtaata ggtaacttta
     8821 tactaggagc tttaatgaca gctggtatag gtttatatgc tccaggtatg gcaatggttt
     8881 atttcttagg aatgtctgca aaagttgcat tcccaatagt tatgggttct tgtgcattat
     8941 taatgccagt tgcaagtatg aaattcataa aagaagatgc atatactaaa aaagcatcag
     9001 ttataatagc tatatgtggt ttaataggag ttttcgtagc tgcatatata gtaaaaactc
     9061 taccaatgga tatattaaaa gcattagtaa tagtagttat agcttatact tctgctacaa
     9121 tgataatggc tgcaaataaa aacaaaaaga ctgcttagtt aaagactact tagtgtttat
     9181 taaatattac agctaataat aaagattata aactgcttta aaatattgaa ttaatatttt
     9241 agggcagttt tttatttact aaattaatat aaagcaatta acatgccaat tatgtaatat
     9301 atatagtgat ttagtagatt taatgtaaaa aacgttgtat ttttaaagaa taaagcataa
     9361 tttaaagcta aatatttaaa ttttataatc aataagttca ataaatgttc atatattaat
     9421 acagattaat aaaaatataa cctgtaataa gtctaatata acttataatt aagaaaaata
     9481 agtttataat gactcaatat tcatctgaat tatttgaata aatttaattc
//
LOCUS       DAMJXI010000107         9511 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.114, whole genome shotgun sequence.
ACCESSION   DAMJXI010000107 DAMJXI010000000
VERSION     DAMJXI010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9511
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.114"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(146..799)
                     /locus_tag="PC465_003472"
     CDS             complement(146..799)
                     /locus_tag="PC465_003472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2650744.1"
                     /translation="MKVDPLTTQVYDYISKKIQNGEYEANQRITESEICKSIGVSRTP
                     AREALTRLAGENLLEKIPNKGFVVKEFQEKEKLDTYSVIGVLDALAGSSALQNLTESD
                     LVKMEELTEMMAVSIKYKNYNSYLKLSNEFHDIYITKSDNQVLVNLLNSLRYNFMSKS
                     YTSDNEDELYKMLTYSNNQHIEVVKSMRENDLENVERVLREHWKTIPMEEMKKEKLL"
     gene            complement(1044..2909)
                     /locus_tag="PC465_003473"
     CDS             complement(1044..2909)
                     /locus_tag="PC465_003473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HDF2650745.1"
                     /translation="MQSVIEYNSWDKNFKAPFGALKFDEELTICVKVNEGYNIKSISL
                     EINREEEMRTITLNEELDNDKLGKCFCGKIEKFDGTGVYFYYFKVDVEMDGQIKTLFY
                     GKNRDNGYSCEYNYSDINKYQITVYKDFKVPTWYKEGILYHIFVDRFNNGNRSGKVDS
                     PKKNSFIYGNWEDTPMYIKDSQGDVIRWDFHGGNLRGIINKLGYLKKLGVSILYLSPI
                     FEASSNHKYDTGDYKKIDPMFGDEDTFKELIDKAKEKGISIVLDGVFSHTGADSKYFN
                     MYGNYNSLGAYQSKESPYYSWYMFEEFPQKYKSWWDVKTLPNINELEHSYMDYIIYDN
                     DSVINKWVNMGIKGWRLDVADELPTKFIRELKKELKKADDDSILIGEVWEDASNKISY
                     GQRRSYLLGEELDSVMGYPFRNNMFSFLKGEINSYELCNRYMQIKENYPKESFRSNLN
                     LIGTHDVTRAKTELNDDVDLVKLAVAIQMTFEGVPYIYYGDEAGLCGGVDPDNRRTYP
                     WKNEDEDMLNFYRDVIKIRNKNKLLSSGNTEFIYTNNDSVFSFIRVNENNDRMLILVN
                     RSENVESISLCIESSFIEEIPIKYSLKNANSTIQIENNELKVDLDSKSFRIFRVN"
     gene            complement(2914..5334)
                     /locus_tag="PC465_003474"
     CDS             complement(2914..5334)
                     /locus_tag="PC465_003474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HDF2650746.1"
                     /translation="MVTISKKKFKQKFEVKMYSLYAQSIKEATDEQLLNVLCSLLKDE
                     IAKKWVATKLDKKKEVYYFSLEFLIGRQLKSNLLNLNIEEEVREGLSELGINLDDLIE
                     AEVDPALGNGGLGRLAACFLDSMASLNISGQGYGIRYKYGLFEQKFVNGYQVEVPDNW
                     LTEGRYAWETVRPNEATMVKFGGEVELIKEGSHLKVIHKNYLPVMAMPYDIPIIGYQN
                     QCINTLRLFKSEIPKRDFGELTSNALNYSGSYEEALKHKYYTEEISQVLYPDDSNYAG
                     KLLRLKQEYFFVSAGIQDIIRKYKKNKLNINNLFDKVAIHINDTHPTLCIPELMRILL
                     DEENLSWDEAWEITKKTVSYTNHTIMSEAMEKWPVSMIKELLPRIYMIIEEINRRYVE
                     ELNNKGYEQDRIKRMSIIDCDNINMANLCIVTSHSVNGVAKLHTHILETEVLKDFYQD
                     EPNKFNNKTNGIAHRRWLISSNPQLSNLITDLIGDSWKKDTLQLKNIEKFKNDSSVLQ
                     RLDDIKYNNKANLAKFIKDKYDLNVDPSSIFDVQVKRLHAYKRQLLNIFNVLHMYHEL
                     LDNPNLNLDPRTFIFGAKAAPGYYLAKCIIKFINSVASTINNDVRVKDKLKVVFLENY
                     GVSLAEIIIPAANVSEQISTTTKEASGTSNMKFMMNGAITLATLDGANVEICEQVGKE
                     NMFLFGLSAEQVLNYNKYGGYSSLDLYHSNMDIKRVVDDLINGFIPNLGEEGRSIYNS
                     LTTYNDEYFVLRDFENYGQAQADINRLYRDKEKWNKMSLVNIANSGFFSSDRTISEYA
                     KDIWFKRV"
     gene            complement(5348..6790)
                     /gene="glgA"
                     /locus_tag="PC465_003475"
     CDS             complement(5348..6790)
                     /gene="glgA"
                     /locus_tag="PC465_003475"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011053260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HDF2650747.1"
                     /translation="MKVFYVTAECWPFAKTGGLGDVSYALPKELKKEGVDVRVIMPKY
                     STIPSYLKDQLKEIAVFSVRVGWRNQYCGLLEMELDGVKFYFIDNEFYFRREDERKSI
                     YGYGDDAERYTFFTDAVLEAISRIDFYPDVIHINDWHTGMLPLILKERYATLEGYKNI
                     KTMYTIHNLQYQGVFDKHVLYDILDLPQKYFDNGDIEYYGSINFMKAGINFADKIITV
                     SPTYANEIQTSFYGEQLDGLLRKESGKLKGILNGIDYDLNDPAKDKDIFVHYDVDSID
                     KKVENKLRLQDILGLKKDSSIPLIGIVSRLVSQKGFDLIAYMMPELMREDLQIVVLGT
                     GEHQYQSMFNYYDSNFSDKVSARITFNASLAQQIYAASDMFLMPSLFEPCGIGQMLAM
                     RYGSLPIVRETGGLRDTVTPYNKFTGEGNGFSFKNYNAHEMFFCLKNAIKVFKDKEKW
                     IKLVENAMKTDNSWKKSAKEYIETYRDICD"
     gene            complement(6819..7949)
                     /gene="glgD"
                     /locus_tag="PC465_003476"
     CDS             complement(6819..7949)
                     /gene="glgD"
                     /locus_tag="PC465_003476"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HDF2650748.1"
                     /translation="MRNECLGIINLNKKGDPAINKLNYGRPIASTPIAGRYRIIDFAL
                     SNMINSGITKVGIFAKEKYRSLTDHIGSGKDWDLSRKKGGLSIFSPENTKYRNTYSHR
                     EGDIYTILANLDYIEKSEEEYILIAPSYMLCNLNYSQALEYHKKSHNDITIIYKNVNN
                     ANKDFAGNLTLNLDSNNRVINVGNNLGKFPRANICMETYIMKREDFVECIYNIVNKGN
                     YCYLEEFIIEEAENMKIGAYEYTGYLKCVNSVESYFEMSKDLLNLEVADELLYSERKI
                     FTKEKNESPTIYTDSAKVENSFIASGCLIEGTVKDSIIFRKVNVEKGTVIENSIVMQN
                     CVIKSNAKLYNAILDKNTSVSNGKELRGDEKYPLVVEKNTNI"
     gene            complement(7951..9111)
                     /locus_tag="PC465_003477"
     CDS             complement(7951..9111)
                     /locus_tag="PC465_003477"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HDF2650749.1"
                     /translation="MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLS
                     NCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGT
                     AHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEA
                     SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDD
                     FGKNLIPKMLEDNVGMYAYPFKGYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIY
                     TNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNV
                     VIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL"
BASE COUNT         3015 a         1732 c          921 g         3843 t
ORIGIN      
        1 ttgatttata tatgttaatt taaatacatt attctatcgt agtgccttag agtttttatt
       61 tgtatttaaa gttaaattta ttcttgtttt tcctttaata tttaatagta aaacaacaaa
      121 attataaaaa aaataaagag aaactttata aaagcttctc ttttttcatc tcttccatag
      181 gtatcgtttt ccaatgttct ctcaaaactc tttcaacatt ttctaaatca ttctccctca
      241 tagattttac tacttcaata tgttgattat tgctgtatgt caacatttta tataactcat
      301 cttcattatc actagtatat gactttgaca taaaattata tcttaaagag ttcaatagat
      361 ttactaacac ctgattatct gatttagtta tgtatatatc gtgaaattca ttacttaatt
      421 ttaaatagct attgtaattt ttatacttta tagagaccgc catcatttcc gttaattctt
      481 ccatttttac taggtctgat tcagttaaat tttgtaatgc tgaagaaccg gctaacgcat
      541 ccaatactcc aattacggaa taggtgtcta atttctcctt ttcctgaaat tcttttacta
      601 caaatccctt attaggtatt ttttctagta aattttcacc tgctaaccta gttaatgctt
      661 ctctcgctgg tgttctacta actccgatag atttacaaat ctcagattca gtaattctct
      721 gattagcttc atattctcca ttttggattt tctttgatat atagtcatat acttgagttg
      781 taagtggatc taccttcata agacgttcct ccatattaag attataaaag ttaaatctcc
      841 ctacaacttt ggtagagagt tcagttttat cttactaatt tatataatat cacaattatg
      901 atatttttta tacttctttg taatattttg aaatactaaa attcttatga taatttatac
      961 aaaaaaagta gaaaaagttt tgataaaaca aaactctttc cacattcacc ttattttcta
     1021 tttatttttc taaaaaaaga tatttaattt actctaaaaa ttctaaatga tttagagtct
     1081 aaatctactt tcaactcatt attttcaatt tgtatagtac tatttgcatt tttaagacta
     1141 tactttatag gtatttcctc aataaaacta ctctctatac ataatgatat actttccaca
     1201 ttttcacttc tatttactaa aattaacatt ctatcattat tttcattaac tctaataaaa
     1261 gaaaatacag aatcattatt agtatatata aattctgtat ttccagaact taaaagttta
     1321 ttcttatttc taatttttat aacatctcta taaaaattaa gcatatcttc gtcttcattt
     1381 ttccatggat aagttcttct attatctggg tcaacacctc cacaaagacc tgcttcatct
     1441 ccataatata tatatggtac tccttcaaat gtcatctgta tagctacagc aagcttcact
     1501 aaatctacat catcatttaa ttccgtttta gctcttgtaa catcatgtgt tccaattaaa
     1561 tttaaattag acctaaatga ttcttttgga taattttctt taatctgcat atatctatta
     1621 caaagttcat atgaattaat ttctcctttt aagaaagaaa acatgttatt tctaaaagga
     1681 taacccataa cagaatctaa ttcttcacct aataaataac ttcttctctg accatagcta
     1741 atcttatttg atgcatcttc ccatacttca cctataagaa ttgagtcatc atctgccttt
     1801 tttaattcct tttttaactc tcttataaac ttagttggta attcgtctgc aacatctagt
     1861 ctccagccct taatacccat atttacccat ttatttataa cgctatcatt gtcatatatt
     1921 atataatcca tatagctatg ttctaattca tttatatttg gcaatgtctt aacatcccac
     1981 caacttttat atttttgagg aaattcttca aacatatacc atgaataata tggagattct
     2041 ttagattgat atgcccctaa actattatag tttccataca tattaaaata tttactatct
     2101 gctccagtat gactaaaaac tccatctaat actattgata tacctttttc ttttgcttta
     2161 tcaataagtt ctttaaatgt atcttcatcc ccaaacattg ggtcaatttt tttatagtca
     2221 cctgtatcat acttatgatt actagaggct tcaaatatag ggcttagata tagtatactt
     2281 acacctaatt tttttaaata tccaagttta ttgattatcc ctcttaaatt tccaccatgg
     2341 aaatcccatc ttataacatc cccttgacta tcctttatgt acataggtgt atcttcccaa
     2401 tttccatata tgaaactatt ttttttagga ctatcaacct taccactacg atttccatta
     2461 ttgaatctat ctacaaatat atgataaagt attccttctt tgtaccatgt tggtacttta
     2521 aaatctttat aaacagtgat ttgatattta ttaatatcac tataattata ttcacaagaa
     2581 tatccattat ctctgttttt tccataaaat aaagtcttta tctgaccatc catttcaaca
     2641 tcaactttaa agtaataaaa ataaacacct gtaccatcaa acttttcaat cttaccacaa
     2701 aagcactttc caagtttatc attatctaat tcttcattta aagttattgt tctcatttct
     2761 tcttctctat ttatttctag ggaaatagac ttgatattgt atccctcatt tactttaaca
     2821 caaatggtca attcctcatc aaattttaaa gctccaaacg gagccttaaa atttttatcc
     2881 caagagttat attctattac actttgcatt taatcacacc cttttaaacc aaatgtcttt
     2941 tgcatactca gaaattgttc tatcagaaga aaaaaatcca gagttagcta tattaactaa
     3001 agacatttta ttccattttt ctttatctct atataacctg tttatatctg cttgagcttg
     3061 accataattt tcaaaatctc tcaatacaaa atactcatca ttgtaagtag tgagtgaatt
     3121 ataaatactt cttccttctt cgccaagatt aggaataaat ccatttatta aatcatctac
     3181 tacccttttt atatccatat tagaatgata taggtcaagt gaagaatatc caccatattt
     3241 attataattt agtacttgtt ctgcactaag tccaaataaa aacatatttt ctttaccaac
     3301 ctgttcacat atctctacat ttgcaccgtc aagtgtagcc aaagttatag caccattcat
     3361 cataaacttc atattacttg ttccagatgc ttccttagtt gtagttgaaa tttgctcact
     3421 aacatttgct gctggtatta ttatttctgc taatgatact ccataattct ctaaaaatac
     3481 tacttttaac ttgtccttta ctctaacatc attatttata gtacttgcaa cagaatttat
     3541 aaatttaatt atacatttag ccaaataata tcctggtgct gcttttgcgc caaatataaa
     3601 agttcttggg tcaagattca aattaggatt atcaagtaat tcatgataca tatgaagtac
     3661 attaaatata ttcagtaact gtcttttata cgcatgcaat ctcttaactt gaacatcaaa
     3721 tatcgaactt gggtctacat ttaaatcgta tttatctttt ataaactttg ctagatttgc
     3781 tttattattg tattttatat catcaagtct ttgtaaaaca gaggaatcat ttttaaattt
     3841 ttcaatattt tttaattgta atgtatcttt cttccatgaa tcaccaatta aatctgtaat
     3901 taaattgcta agttgaggat ttgaacttat aagccatcgc ctatgtgcaa ttccattagt
     3961 cttattatta aatttatttg gttcatcttg atagaaatct tttaatacct ctgtttcaag
     4021 aatatgagta tgaagcttag caactccatt tacactatga cttgtgacaa tacataagtt
     4081 tgccatattg atattgtcac agtctattat actcattctt tttattctat cctgctcata
     4141 tcctttatta tttaattcct ctacatatct tctatttatt tcttctatta tcatataaat
     4201 tcttggtaat agttctttaa tcatacttac aggccatttt tccattgctt ctgacattat
     4261 agtatgatta gtataggaca ctgttttttt agttatttcc catgcttcat cccaagataa
     4321 attttcttca tcaagcaaaa ttctcataag ttctggtatg cataaggtag gatgtgtatc
     4381 atttatatga attgctacct tatcgaataa attattaata tttaatttgt tctttttata
     4441 ttttcttatt atatcttgta tccctgcact tacaaaaaag tattcttgtt tcaacctcaa
     4501 caacttacct gcataatttg aatcatcagg atataatacc tgtgatattt cctcagtata
     4561 atacttatgt tttaaagcct cttcatagct accagaataa tttagagcat ttgaagtaag
     4621 ttcaccaaaa tctctctttg gtatttcact cttaaacaat cttaaagtat ttatacattg
     4681 gttttggtat ccgattattg gtatatcata aggcattgcc attacaggaa ggtagttttt
     4741 atgaattact tttaaatgac taccttcctt gattaattct acctcaccac caaacttcac
     4801 cattgttgct tcatttggtc ttacagtttc ccatgcatat cgtccttctg taagccagtt
     4861 atcaggcact tctacctgat aaccatttac aaatttttgt tcaaacagac catatttata
     4921 ccttattcca tatccttgac cacttatgtt caaagatgcc atagaatcta aaaagcaagc
     4981 tgctaatcta ccaagtccac catttcctaa ggctgggtct acttcagctt caattaaatc
     5041 atccaagttg attcctaatt cagatagacc ttctctaact tcttcttcaa tatttaaatt
     5101 taataaatta gattttaact gtctccctat taaaaattct aaactaaaat aataaacttc
     5161 ttttttctta tctaactttg tagcaaccca tttttttgct atctcatctt tcaatagact
     5221 acataataca tttaacaatt gttcatcagt agcttccttg atagattgtg catataagct
     5281 atacattttt acttcaaatt tttgcttgaa tttctttttg cttattgtta ccaaaaaaac
     5341 cactccttta atcacatatg tctctatatg tttctatata ctccttagct gattttttcc
     5401 aactattatc tgttttcatt gcattttcaa ctaatttaat ccatttttct ttgtccttaa
     5461 atactttgat tgcatttttc aaacagaaaa acatctcatg agcattgtaa tttttaaaac
     5521 taaatccatt gccttctcca gtaaatttat tataaggtgt tactgtatct ctaagccctc
     5581 cagtctctct aactattggt aaagaaccat atctcatagc taacatttga cctataccac
     5641 aaggctcaaa taatgatggc attaagaaca tatcacttgc agcatatatc tgttgagcca
     5701 atgatgcatt aaaagtaatt ctagctgata ctttatctga aaaattagaa tcgtaatagt
     5761 tgaacattga ttgatattga tgttctccag ttcctaaaac gacaatctgt aaatcttctc
     5821 tcataagttc tggcatcatg tatgctatta aatcaaatcc tttttgagaa actaatctcg
     5881 aaactatacc tatcaacgga atagatgaat ctttttttag tcccaatata tcttgtaatc
     5941 tcaatttatt ttctactttt ttgtcaattg agtctacatc ataatgaaca aatatatctt
     6001 tatcttttgc agggtcattt aaatcataat ctataccatt taatatacct tttaattttc
     6061 ctgactcttt tctaagtaat ccatctaatt gttcgccata aaaagatgtt tgtatttcat
     6121 ttgcataagt agggctaaca gttataattt tatctgcaaa atttatacca gctttcataa
     6181 aatttattga gccataatac tctatatctc cattatcaaa gtatttttgt ggtaaatcca
     6241 atatatcata taaaacatgc ttatcaaata caccttgata ttggagatta tgtatagtat
     6301 acatagtttt tatattttta tacccctcaa gggttgcata tctttctttt agaattaatg
     6361 gtaacatccc tgtatgccaa tcatttatat gtattacatc tggataaaaa tcaattctac
     6421 ttatagcttc taaaactgca tctgtaaaga aagtatatct ttctgcatca tctccatatc
     6481 catagatact ctttctttca tcttctcttc taaaataaaa ttcattatct ataaagtaaa
     6541 attttacacc atctaattcc atttctaaaa gaccacagta ttgatttctc catccaacac
     6601 gtacactaaa cacagctatt tcttttagtt gatcttttaa ataacttggt atagttgaat
     6661 atttgggcat tattaccctt acatctacac cttctttttt taattcttta ggcaatgcat
     6721 aagaaacatc tcctaatcct ccagtttttg caaagggcca acactctgct gttacataaa
     6781 aaaccttcat tagtcattcc cccttctaaa aaatttattt atatatttgt attcttttcc
     6841 actacaagag gatatttttc atctcctctt aattctttcc catttgatac actcgtattt
     6901 ttatctaata ttgcattata tagttttgca tttgacttta ttacacaatt ttgcattact
     6961 attgagttct ctataactgt tcctttttca acatttacct ttctaaatat gatactatct
     7021 tttacagtac cttctattaa acaaccagat gctataaagc tattttctac tttagcacta
     7081 tctgtataaa ttgtaggtga ttcattcttt tcttttgtaa atatctttct ttcagaatat
     7141 aataattcat ctgcaacttc taaatttaat aaatctttgc tcatttcaaa atatgattca
     7201 acagaattta cacattttag atatcctgta tattcatagg ctcctatttt catgttttct
     7261 gcttcttcaa taataaattc ttctaaataa caataattgc ctttatttac aatgttatat
     7321 atacattcaa caaaatcttc acgcttcata atatatgtct ccatacatat gtttgctcta
     7381 gggaacttac ctaaattatt tcctacattt attaccctat tgttactatc taaatttaga
     7441 gttaagttac cagcaaaatc tttatttgca ttatttacat ttttatatat tatagttata
     7501 tcattatgag attttttatg gtattccaat gcttgagaat aatttaaatt gcatagcata
     7561 tagcttggag ctattaaaat atattcttct tcactctttt ctatataatc tagattagct
     7621 aagatagtat atatatcacc ttctctatgt gagtaagtat ttctatactt agtgttttct
     7681 ggactaaaaa ttgataggcc accttttttt ctacttaaat cccaatcttt accactacct
     7741 atatggtctg ttaatgatct gtatttttct tttgcgaata ttccaacttt agtgattcct
     7801 gaatttatca tattagataa agcaaagtct attattctat atcttccagc tattggtgta
     7861 gatgctattg gtcttccata gttaagtttg tttattgctg ggtctccttt tttgtttaaa
     7921 tttattatcc ctaaacattc atttctcatc ttaaagacct ccttctatta atacgcatct
     7981 aggttcgata ttttcatact cagaaactac atttatttca ttatttacat tctttatctg
     8041 aacattatca tttatagttg cacactcacc tatcatagct ttttctatag ttacattttc
     8101 acctattaca acatttggca ttattactga atcaattact ttacttcctt ttccaacaac
     8161 aactccatgt gataatacag agttacctac ttcacctaaa attctacaac catcagctat
     8221 cattgatcta tgaacatttg catttttacc tatatattgt ggaggcattg ccatagtatt
     8281 tgtatatatc ttccatttag ggtctgctaa atcaagtgtt tctggagatt ttattatatc
     8341 catattagca tcccatagac tttgtatagt tcctacatct ctccagtatc ctttaaatgg
     8401 ataagcatac attccaacat tatcttctaa cattttaggt attaaatttt ttccaaaatc
     8461 atcataattt atttctggat ttttttctgc ttccttaaaa taatttctca acattttcca
     8521 atcaaatatg tatactccca tagatgccaa attgctctta ggttcacttg gtttttcttc
     8581 aaattcatag atacttgaat cttcatttgt attcattatc ccaaatcttg aagcttcatc
     8641 ccaaggaact tcaatcactg ctattgtagc tttagagcct ttttccttat gaaattttaa
     8701 cattttgcta taatccatct tgtatatatg gtcaccagat aatatcaata catattctgg
     8761 attataggta tctacaaagt ccatattttg atatatcgca tgtgctgtac cattatacca
     8821 atttccttct ttttcattca taaatggttg taaaacatag acaccaccat ttattctgtc
     8881 caaatcccaa tgacttccca ttcctatatg tgaatttaat atcaacggtc tatattgagt
     8941 taaaacacct acagtatcaa taccagagtt tgaacaattg cttaacacaa aatctataat
     9001 tctatactta cctccaaatg atacagctgg tttggcaatt ctttttgtaa aaacacctaa
     9061 tcttgaacct tgccctcctg ccaaaatcat agctaacatc tcttttttca tttaatgaca
     9121 ctcccctcat ctagtaatta atatttataa ttgcattttt acttttataa actttatcag
     9181 tcaataaatg tcgtgtataa atgttgctta aataatacct taataaaaat aaaataatat
     9241 caactataca attgatataa tgtatacccc ataatgaact taccgacgta tacattattt
     9301 tccataagca ctatagtatt tattaatatt caattatcgg ttaaaaaata atacaaattt
     9361 tattttataa atataaaaac attttttata aatctcttgt gtcatatgaa catgcttatt
     9421 ttttaatttg ttaaattcgt aatagcaaaa tataatctaa tatttgttaa ataattatcc
     9481 aaggaaaatc aagtaattat taatcaactt t
//
LOCUS       DAMJXI010000108         9191 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.115, whole genome shotgun sequence.
ACCESSION   DAMJXI010000108 DAMJXI010000000
VERSION     DAMJXI010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9191
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.115"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            393..1598
                     /locus_tag="PC465_003478"
     CDS             393..1598
                     /locus_tag="PC465_003478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDF2650750.1"
                     /translation="MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDS
                     LKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFK
                     KLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTEHFYKHYTNTINVPPLIS
                     VLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVEPSKIRTFGIPVEKSFLSHRDKD
                     IVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTDRDFQILVITGKNESLKEKIE
                     KKLMSRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPG
                     QEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNIKSIRKSNSAQNIA
                     NLILNIISG"
     gene            complement(1669..1890)
                     /locus_tag="PC465_003479"
     CDS             complement(1669..1890)
                     /locus_tag="PC465_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650751.1"
                     /translation="MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTK
                     KNVRNKNAEFRNNYKNYQYDYEEDFYEPI"
     gene            complement(2031..2630)
                     /gene="recR"
                     /locus_tag="PC465_003480"
     CDS             complement(2031..2630)
                     /gene="recR"
                     /locus_tag="PC465_003480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012634696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HDF2650752.1"
                     /translation="MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEAL
                     SKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFK
                     GQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARL
                     VKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI"
     gene            complement(2643..2993)
                     /locus_tag="PC465_003481"
     CDS             complement(2643..2993)
                     /locus_tag="PC465_003481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HDF2650753.1"
                     /translation="MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVE
                     ASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQ
                     MSKVTGGMNIPGLF"
     gene            complement(3052..4689)
                     /gene="dnaX"
                     /locus_tag="PC465_003482"
     CDS             complement(3052..4689)
                     /gene="dnaX"
                     /locus_tag="PC465_003482"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HDF2650754.1"
                     /translation="MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCG
                     TRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDD
                     IRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHK
                     IPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALS
                     ILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKD
                     IRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILS
                     ITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGN
                     NKEKEYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEV
                     KSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKD
                     INLEVKEKKDIGEEILKNIVSEEILEIKDSIDENESK"
     gene            complement(4766..5030)
                     /gene="ffs"
                     /locus_tag="PC465_003483"
     ncRNA           complement(4766..5030)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="PC465_003483"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            complement(5068..5159)
                     /locus_tag="PC465_003484"
     tRNA            complement(5068..5159)
                     /locus_tag="PC465_003484"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5123..5125),aa:Ser,seq:gga)
     gene            complement(5160..5615)
                     /locus_tag="PC465_003485"
     CDS             complement(5160..5615)
                     /locus_tag="PC465_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HDF2650755.1"
                     /translation="MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTE
                     TLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTR
                     HVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD"
     gene            complement(5936..7207)
                     /gene="serS"
                     /locus_tag="PC465_003486"
     CDS             complement(5936..7207)
                     /gene="serS"
                     /locus_tag="PC465_003486"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDF2650756.1"
                     /translation="MLDIKRIRENLDDIKKAMERRGEREFDLDAVVELDNKRREILQE
                     VEVMKNELNVNSKKIPQLIKEGKDVTEEKARLKELSDKIKGIDEKVKEVEAKMEYTLM
                     RIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEHKAHWDIGTGLGILDFERAGKITG
                     SRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDM
                     FKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFK
                     YDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRC
                     LAAILENYQQADGSVVVPEELRPYMGVDVIK"
     misc_binding    complement(7333..7538)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7666..8547)
                     /locus_tag="PC465_003487"
     CDS             complement(7666..8547)
                     /locus_tag="PC465_003487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HDF2650757.1"
                     /translation="MNFLSLAKTASTNSNITKRTLENMLDNFSDNIPNIIYAIIVFVI
                     GIYISKIVRRMVSKFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGIIGIQTTSVVA
                     VLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLK
                     TPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDVVKSILNEIFTNEKR
                     ILNDPKPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENDIKVPFVP
                     SSLLFNNTGNLNTMDKR"
     gene            complement(8559..9068)
                     /locus_tag="PC465_003488"
     CDS             complement(8559..9068)
                     /locus_tag="PC465_003488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HDF2650758.1"
                     /translation="MNSNERRSKLIDILKESKHPVKGGTLAELLNVSRQVIVQDIALI
                     RARGFEIIATPQGYIIYNQPYFTKQIKCKNHKDSKEIYDELKIIVDLGGIIKDVIVNH
                     PTYGQITAELNIYSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIEAIKEETIEAIVK
                     ELKDNGILS"
BASE COUNT         2941 a         1600 c          975 g         3675 t
ORIGIN      
        1 ttcctttttt caaggacaag taatactata tcatctttat ctattctagt caatataatt
       61 ttttactttt tttatttttt ttatttatca tgtattcttt atatttaatt tttaaaactt
      121 aatgctaagt aaacctgttt atttcataaa actaatatat attctatgct ctattttcct
      181 ttttattcta tatttaaatt ttttatttac aagaatattt ttaatataac atatttgata
      241 aaattaattt acatttcttt cacttgtaat ttttgcaatc ttgtattaga ttaatattaa
      301 aaataattta tcaataacct tattcacaaa gacagttttt atatatcaaa atataatata
      361 aatactatgc tacattttag gaggatttta ttatgagcaa aaaagtatta ataatgtctg
      421 cttccactgg tggtgggcat aatagggctg ctctagctat taaagaagaa cttacttcca
      481 aaacacttga tggagagcca attgaatgtg aaataataga tagtttgaaa ttagttaata
      541 atacaatgga taaaataatt tcaagaggat acgaaaaatc tgctatatat actcccaaag
      601 cctatggaag tgtatataga ttatctgaaa caaatctttt gtcaaaaaat gaatttaaag
      661 ataatctact aataacattc atggctaaaa aatttaaaaa gcttattaga agcgaaaaac
      721 cagacttgat tataggaacg catccttttc caatgattgc tctaagtaca ttgaaaaaaa
      781 actttaattt acataataat gaatcaaatg cttacacaga gcatttttat aaacattata
      841 caaataccat taatgttcct ccgcttattt ctgtattaac cgattatact actcattcta
      901 catggataca aaatgaaatt gattactata ttgttggtca tgaatatgta aaagaattat
      961 tggtgtttga tggagttgaa ccgagtaaaa ttagaacatt tggaatccct gttgaaaaat
     1021 cttttctctc tcacagagat aaagatattg ttctttctga gttgaattta tctcctgata
     1081 aattaactgt tttacttatg gggggtagct ttggggctgg aaatataaaa gagacacttg
     1141 atgaattact ggatactgat agagactttc aaatacttgt aattactggt aagaatgaaa
     1201 gcctaaaaga aaaaatcgaa aaaaaactta tgtctcgtta tcatgataaa aatgtatgtg
     1261 ttcttggata cactgataag atgaatgata ttttagcttc tatagatgta ttagtaagca
     1321 aacctggtgg acttactaca actgaggctc ttttaaaaga tgtacctatg atagttcctt
     1381 attatatacc aggtcaggaa gaagagaatc ttgatttctt atctaattgt ggtgcagcac
     1441 ttagaactac aaaaaaatat aacttgtcaa tattactaaa agttttaata gatgacccta
     1501 gcagattaga aatgctaaaa agaaatatta aatcaataag aaagtcaaat tcagcccaaa
     1561 atatagctaa tttaatttta aatataattt ctggttgata aaataaataa aatccctata
     1621 gtatatatat tatctattag ggatttttta ttttctaatt atttaatatt aaattggttc
     1681 ataaaagtct tcttcataat catactgata atttttataa ttatttctaa attcagcatt
     1741 tttatttcgt acattttttt tagttttttt cttattagaa aaacttatat cctcaaaatc
     1801 atcatattta ggtttatctt ttgatttcat ttttttaact cttttttctt tcattgcatt
     1861 atgttcttct aagttcataa ttggtttcat gttgcacccc tatcaaaatt tttaaatgat
     1921 ttatacaaca aattatacaa tacagaagaa atttattcaa taaatctaaa tcaaaattaa
     1981 tttgaattta actcaaaaaa ttacaaaaat cgaggtatta acctcgattt ttatatttct
     2041 cttctgcctt ctagtgcttt tgatattgtg acctcatctg catactctaa atcgcctcca
     2101 acaggaagac catgagctat ccgagtgact ttgattccca ttggttttac taacctagca
     2161 atatacatgg ctgtagcttc accttcaata gtaggatttg ttgccattat tatttctttg
     2221 acttcctgat tgccaagtct ttggataagt tcctttattt ttaacatatc tggtccaatt
     2281 ccatccattg gagaaattac tccatttaat acatgatact gtcctttaaa ctctctcgtt
     2341 ctctccatag ctgctacatc tcttggatct tccacaacac atataacact tgaatctcta
     2401 cttttatttg aacacatgct acatgggtct gtatctgtta tattacaaca aattgagcaa
     2461 tatcttattt ctctttttgc atctataatc gctttagata aagcttccac atcattagta
     2521 ttcatattaa taatatgaaa agccaatctt tgagcagtct ttcttcctac tccaggaagc
     2581 tttgaaaatt cctctataag tctcgttatg ggacctgtat aaacttgcat aaataccacc
     2641 tactagaata acccaggtat attcatacct ccagttacct tactcatttg acttgcttgt
     2701 atatcatcaa tatttctcaa tgcttgattt actgcactta aaactaaatc ttgtagcatt
     2761 tctatatcat ctggatcaac tacttctggc ttgatagtta tatctataac ttctttttta
     2821 ccattaactt ttacagtaac tgctcctcca ccaactgaag cttctacttc tttactttct
     2881 aactcttgtt gagctttttg catattttct tgcatttttt gagcctgctt taacaagttg
     2941 ttcatatttc caccaccagg catcattccg cctccaaaac cttttttagc cataaacact
     3001 attcctccta aacttatttt cattttatta ttatatcata atagtatttt attatttact
     3061 ctcattttca tcaatactat cttttatttc taatatctct tcactcacta tgttctttaa
     3121 tatttcctca ccaatgtcct ttttctcttt aacttcaaga tttatatctt taacttctga
     3181 tgtcagtact atttttacat taaaacttct atttaaaaca tctcttattg ttttttctaa
     3241 ataatttatt gtatcttgag agctcagtct agtttttgca aaatcaaatt tatcatcaaa
     3301 tataacatac aacatattag aatatacatt aaaacttttt acttcactta agagtgcgta
     3361 tattggcatt tttttatctt ttttaatttg tttaagtata ttcttccaag atgactctat
     3421 aagtataacg tcctcatttt ttacatcttc ataaactaca ttttcttgtt ttacatctat
     3481 ttctctatcg acctcatact ctttttcttt attattccca attttttcag acttaaagtt
     3541 ccccagttca atcatttttt ctaagttctc aactcttttt ataagagctt ctttactttc
     3601 atcaaacatt ggttgagcaa ttttcattat ggttatttcc actaaaaccc ttggatttga
     3661 agatgacttt atatcatcct gagttattga taatatattt aaaatcctta ttaaatcatt
     3721 tatatctata tttttagact gaattttaag ttgttctata gtttcttctg gtaatgaaat
     3781 tatttcatcc aattctgatg aaaccttaca taccattaaa tttctaaaat gatcaattaa
     3841 gtcatttata agatttctta tatctttgcc ccataagaca aattcattta atatctcaag
     3901 agacttttta gtgtcctgct ctacaataca ttgagacaat tcaaataatt gttctatatt
     3961 tacgcttccc attaattcaa caacatcttt ataatctatc ttactttctc caaaagacat
     4021 acattggtct aatatactaa gtgcatctct aagagctcct tgagaatttc tagctattaa
     4081 attaagagct ttatcatcta tatcaattcc ttcatcttca caaatctttt tcattctaag
     4141 ggtcatatct ttaactgtaa ctcttttaaa atcgtatctt tggcatcttg ataaaatggt
     4201 tgcaggtatt ttgtgaggct ctgtagttgc taatataaaa attacatatg atggaggttc
     4261 ctctaaggtc tttaataatg cattaaaagc tccttgagac aacatatgaa cttcatctat
     4321 tatatatact ttatatttag cattggctgg agaatatttc acactttctc taagctctct
     4381 tatatcatct acactattat ttgaagctgc atctatttct acaacatcca ttgtattatc
     4441 ttttaataca gattcgcata tctcacactc attacacggt tcttcattta ttttattcaa
     4501 acagtttact gctcttgaaa aaatctttgc agtagatgtt ttaccagtac ctcttgttcc
     4561 acaaaacaaa taagcatgtc ctatattatc actatatatt tgattcttta aagtcttaat
     4621 aatatgatct tgaccaataa catcttcaaa tttttgtggt ctatatgctc tatataatgc
     4681 tttatgcatc tttttacctc tctttagcaa aattaataaa aaaatccctc attatctaag
     4741 ggattagtct tttatatatt aaatgctgta caccatctat cgacttaatt ccataggcgt
     4801 taccaaaaca gttagctcaa cttaggcacc cccacggcac acaaaagtga tcacttaccg
     4861 ctgcttcctt ccggatctga cggggttcat gagctttcat tgcgcaggac ctaagcatca
     4921 acaccactta tttagggcgg ccctacagaa aataagcctt tagatggaat tcaatcctgc
     4981 tatagcggat tgcaggttac agggcaccgc tacctcccca tctagtacag caaaattaca
     5041 accatattta attactttca ttgtttctgg cggagagagt gggatttgaa cccacgatac
     5101 agttttaccc atatactcgc tttccaggcg agcgccttcg accactcgac catctctcct
     5161 taatctcttt ttctcaatgc cttaaaaaat tcttgcaata tgatcgagca ttcttcttgc
     5221 aaaacatcaa aagctacttt tacattatta ttattaaaat aatctaattt aaactcatgc
     5281 tgtttttcta tatatgaatt ttttacatgt cttgtcccta ttataagctt ttttattcta
     5341 gaattaacta ttgcgccact acacattatg caaggttcca ttgtaacata taaatcacaa
     5401 tcagtcaacc tccaaccacc taatttttct gatgcttgtt ttatcgctaa aatttctgca
     5461 tgtgccgtag agtcttttaa cgtttctgta aggttatgag ctctagctat tatttgatta
     5521 tctttaacta taatagcacc tattggtgtt tcttttttat tatatgcttt atatgcttct
     5581 tttaatgctt ctttcatata aaatgaactt tccataattc ctcccaaaac ttataacaaa
     5641 cttatcttat cataattcat tttataattc aacttaattt tattttgttt atttaattat
     5701 tactatatat agctatattt tttttaaatt agttctaaaa taatttttag atattcatac
     5761 aagagtgttt tataaaaata tttagtgttt tatgatgaaa attctgctgt gtaaattaac
     5821 ataaaaaaac tatgaaatta atatttataa caatttcata gtttttttat ttattgttta
     5881 ctcataatat attctcttca tcaaagcata ctctacatat acaattaata taaatttatt
     5941 ttataacatc aacacccata taaggtctta attcttctgg aactactaca gaaccatctg
     6001 cctgctgata attttctaat atagcagcca aacatcttcc tatcgctaat ccagaaccat
     6061 ttaatgtatg aacatattct gcttttgatt ttttatccct tttaaatctt attcctgctc
     6121 ttcttgcttg gaaatcttca aaatttgaac aagaagatat ttctacatat ctattgtagc
     6181 ttggcatcca aacttctaaa tcatatttaa atgcagctgt aaatcccaaa tctcctgtac
     6241 atatttttac aactctatat ggaagaccta acatttgtaa catagtttca gcatcatgag
     6301 ttaatgattc taattcatta taagaatctt ctggtttaac aaatttaact aattcaactt
     6361 tattaaattg atgttgtcta actaaacctc ttgtatctct tcctgctgaa cctgcttcag
     6421 atctaaaaca aggagtatat gcacagtatt taattggaag ctctgcaaca tctaatattt
     6481 cattagcatg tatattagta acaggaactt cagctgttgg tattaagaaa tactctaatc
     6541 cttctatttt aaacatatct tcttcaaatt taggaagttg accagtccct ataaaactat
     6601 ttctattggc cataaatgga ggtaagactt ccgtatagcc atgcttagct gtatgagtat
     6661 ttaaaaagaa attcattaaa gatctttcta atctagctcc taatccccta tataaagtaa
     6721 accttgaccc agttattttc cctgctcttt caaaatctaa aatacctaga cctgtaccta
     6781 tatcccaatg cgctttatgc tcaaaatcaa atttagtagg ttctccccaa gttcttattt
     6841 gaacattgtc ttcatctgtt tcaccttgtg gtacctctgg atgaggaaca tttggtattc
     6901 tcattaatgt atattccatt tttgcttcta cttcttttac tttctcatca atacctttta
     6961 tcttatctga taactctttc aatcttgcct tttcttctgt tacatctttt ccttctttta
     7021 ttaattgagg tattttttta gaatttacat ttaactcatt tttcataact tcaacttctt
     7081 gaagtatttc tcttctttta ttatctaatt ccactacagc atcaaggtca aattctcttt
     7141 cacctcttct ttccatagct tttttgatat catctagatt ttctcttatt cttttaatat
     7201 ctaacatatt aattcctcct aataattttg ataatataag ttataattcc aacttaattt
     7261 acaaacatta tacttgtaaa ctcttagttt aaacaaattt taaaaataaa aaaagacctc
     7321 cgtttaccct ataaaaggga cgaaaatctt ttatccgcgt tgccacccta attgactata
     7381 ctaaaatgta taatcctctc agacctataa cgtaggtaaa cgtctagctt taactagaag
     7441 ctctagagta gattcaaaaa ccattgtaat gagttttcac catccactca ttctctgaat
     7501 acaatctgtt ttttactatt ttccttcaca gctttttaac taattgtttt atttgataat
     7561 cattatatta tatatattaa catctttcaa tactattatt caaatttttt tagaattttc
     7621 tttaattttt tatattaaat tcattttttc tatttaatta agaccttatc ttttatccat
     7681 tgtatttaga ttacctgtat tattaaataa taatgaagaa ggaacaaatg gaacttttat
     7741 atcattctca tcaaatttat tttttacctt ttccattaca tcaaagtata catcccagta
     7801 atcatcagtt tttacccaag gtctagcaac tatttgcatg gtgttatttc ctatagagtt
     7861 taaacctatt ataggctttg gatcatttaa tattcttttt tcgtttgtaa aaatttcatt
     7921 taatatagac ttaactacat ctatatcact atcatatgaa atattatatg aaaaatctat
     7981 tcttcttttg ttttgatgtg tgtaattaat tatattatta cttgtcagtt gaaaattagg
     8041 tataattata gttttattat ctggtgtctt aagaacagtg ctaaatattt gtatgtcaga
     8101 aactgtacct tctacacctg aaccttgaat ataatcacct atattaaatg gcttaaaaaa
     8161 taaaataatc ataccagagc ctaaatttga taatatttct ttaaaagcta aacctatact
     8221 aaatccagca gctcctaaca cagctacaac tgatgtagtt tgtatcccta taatacctaa
     8281 gcttatcaat gatataatag ataacataga tatatatatt ccatatacaa taaaattatt
     8341 tacaccttta ctcattccat atttgattag aaactttgaa accatccttc ttactatttt
     8401 agatatataa atacctatca caaatacaat tattgcatat ataatatttg gtatattatc
     8461 actaaaatta tcgagcatat tttctaaagt tctcttagtt atattgctat ttgttgaggc
     8521 agtcttagcc aatgataaaa aattcattca actcctcctt atgataatat tccgttgtcc
     8581 tttaactctt ttactatagc ttctatagtt tcttctttta ttgcctcaat tgtatgaata
     8641 tggctacatt ctgtcagaac cgataattgt ttaaattcat ttgtctcaac tttcttcata
     8701 aagttgtcta tatccatttt agaataaata ttaagttctg cagttatctg accatatgtt
     8761 ggatgattta caatgacatc ttttataata ccacctaaat ctacaattat ctttaattca
     8821 tcataaattt ctttagaatc cttatgattt ttacacttta tttgttttgt aaaatacggt
     8881 tgattatata ttatatatcc ttgaggtgta gctattattt caaatcctct agctcttata
     8941 agggctatat cttgaactat tacttgccta cttacattta atagttcagc tagtgttcca
     9001 ccttttacag gatgcttaga ttcttttaaa atatctatta atttacttct tctttcatta
     9061 gaattcatat tacaccttct ttccaaataa aaactttacc tatactatat aattttatat
     9121 tttatcttat tataaatcaa tattgacttt atattctatt taatcttaac ttttataata
     9181 aataaaaaag a
//
LOCUS       DAMJXI010000109         8959 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.116, whole genome shotgun sequence.
ACCESSION   DAMJXI010000109 DAMJXI010000000
VERSION     DAMJXI010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8959
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.116"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(333..1229)
                     /locus_tag="PC465_003489"
     CDS             complement(333..1229)
                     /locus_tag="PC465_003489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2650759.1"
                     /translation="MKDKNTYFNRKGQENFIDIFLKDDIKKGANFKRHWHEHLQIYYF
                     IDGIAYLECGLDNFKVVPGNIVIANSNELHYLESLSDNLKFYSIRIEPTFLFSNQVDL
                     LQTKYLAPLALNHIVFNNLIQNDSLILKCITTILDEYHNKEVGYELSIKANIYQLIVL
                     LLRSHIDKIYSEDEFIKRKYSLEKFECIFDLIEEKYMDKITLKELASRVNLSAHHFCR
                     TFKQITGKTTIDFINGIRLDKAIYYLKETDLNMTEIAMRCGFDSINYFSRLFKRNYNI
                     SPTKYRNEHREVSNVILKEDMK"
     gene            1371..2798
                     /locus_tag="PC465_003490"
     CDS             1371..2798
                     /locus_tag="PC465_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2650760.1"
                     /translation="MTNSFKKDDNRKKITVLFVVIAMTFMATLDSSIINVALPVLASK
                     LNVSLASIEWVIASYSIIICSTLLFFGRLGDIIGKSRVFQVGTILFTSASLLCGLSNS
                     LTLLIVCRFIQGIGASAYMANNHGIITELFPKESRGKALGILVTAVAIGNMVGPSVGG
                     FILSIFDWNVIFFINIPIGLIVIFLNTKFLPNSKKSSENMDKTGAILQFLGTTLFFSA
                     LISAQQTGLLNPYILIALLLSIIFIILFLILEKKHPQPLLDLEIFRSFKFSLNLICAL
                     TSFICIASSSILIPFYLQSTMKLPPIQAGLFMILSPLILAIFSPIFGNISDKIKSEKI
                     ILIGLLVMSFGFFLMSRLKESSALILFVIYISIISIGQAIFQPANNALIMSSCSRSKL
                     GVVGSINSLVRNLGQVIGITISTTLLYNFMSIKAGYRVNDYVINNDKIFVFGMRNVYI
                     IVTLVCLIGAILIGFYLFKYNKNEQ"
     gene            complement(2994..5588)
                     /gene="clpB"
                     /locus_tag="PC465_003491"
     CDS             complement(2994..5588)
                     /gene="clpB"
                     /locus_tag="PC465_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HDF2650761.1"
                     /translation="MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDG
                     LIPNIIEKMNISIDSLRNTVNFEIDKLPKVYGEGADSQGVSATRKINEVLIKAESISK
                     EFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNDFLNILSQVRGSQRVETQDPE
                     GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKT
                     AIVEGLAERIVRGDVPEGLKDKIVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDG
                     KIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATTFDEYRKYIEKDKAL
                     ERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSHRYIQDRFLP
                     DKAIDLIDEAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQ
                     KEIAELKSKNDEMTAKYEKEKSQILDIKNLKAQLDEAKGKAEKYEREYDFNKAAEVKY
                     GEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVEGEREKL
                     LKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKT
                     LARNLFDSEDNIIRIDMSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVIL
                     FDEIEKAHEDVFNMFLQILDDGRLTDNKGKTVDFKNTLIIMTSNIGSNYLLEAGGNIT
                     ETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDIT
                     IEVTNSAKDVMVREGYDPVYGARPLKRYIGNTLETIIAKKLIAGDVYNGCTIVIDGKD
                     ENIEVLVK"
     gene            complement(5625..6221)
                     /locus_tag="PC465_003492"
     CDS             complement(5625..6221)
                     /locus_tag="PC465_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650762.1"
                     /translation="MSLKLDRNVLQWFDYVFENEKTSLRHYNFNCTLKEISSTSLNKV
                     AFILEKNNSKYWKLYFEIPAEVTLKLKQNIHPLFREYIYEQISLYNNNQIYNFVNSNI
                     LKVFNNIAIYQYNILENLYTIDFKKSFIDKCQYLLIGEKRLIDEDLYLIAKSKEVFDF
                     FNSDGTFNLTLSFDIQKNENLLDSLLELRKSIIINERI"
     gene            complement(6238..6642)
                     /locus_tag="PC465_003493"
     CDS             complement(6238..6642)
                     /locus_tag="PC465_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication/maintenance protein RepL"
                     /protein_id="HDF2650763.1"
                     /translation="MDKTLKKDLNQEYTESKSLVMNKSKYMNVCFKNYIKVVEGMYTK
                     KDLIPLKLINSMDKNNKIRKTLYELSCEFEYPKTSLSSLFTELKKMDFLQRVKNGEYM
                     INPHIVYKGSRADKESLLAEYNQIKRPNKVSK"
     gene            7009..7383
                     /locus_tag="PC465_003494"
     CDS             7009..7383
                     /locus_tag="PC465_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2650764.1"
                     /translation="MNIVISNSSGKPIYEQITTQIKSMIISGELPEGSALPSMRLLAK
                     ELRISVITTKRAYSDLERDGFIETVTGKGSFVSSKNMDFVKEEQFRLIEEYLQKAVDT
                     AKSSDITYDELKDILFLLYKGE"
     gene            7380..8243
                     /locus_tag="PC465_003495"
     CDS             7380..8243
                     /locus_tag="PC465_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2650765.1"
                     /translation="MISMDAITIKNLNKTYKDFSLQDISFSVPKGSVMGFVGENGAGK
                     TTTLKAILNLISYDSGNIEIFGLDSKKNEKEIKEQIGVVFEGSNFHENLNTDHVSKIM
                     SKIYKNWNDTLFKDYLKKLRVPDNKLIKEFSKGNKMKLSIAVALSHKPKLLILDEATS
                     SLDPIVREEILDIFLDFIQDEEHSIILSSHITSDLDKIADYITFIHKGKIVFSENKDE
                     LIDTMGVLKCKPSDFDNLSREDYSYYRKSQFGYEVLLKDKHRFISRHPNCIVDNTSIE
                     EIMLFYVRGDK"
     gene            8243..8881
                     /locus_tag="PC465_003496"
     CDS             8243..8881
                     /locus_tag="PC465_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HDF2650766.1"
                     /translation="MKGLILKDLLNLKGNIKFILLFIIMFGFMSSLGDGNVNNFIGVI
                     IVLCTTMIVSTFSYDDLNKWDSYVLTMPINRNDIVLSKYLTMLIFSFIGVLVSLIVSV
                     TIGYFKNTLILNETLLINALILSISVCFGSLILPLIYKFGIERARLLMILCFLVPTLA
                     LLVFKSILENISSPISIEIILNTLVYSLPFVAILLFVISYFISSKIYSKKEV"
BASE COUNT         3002 a         1318 c         1028 g         3611 t
ORIGIN      
        1 gatttaaatt ttctataaaa atcatactat tttagctgtt tacttgctta tttaatagtt
       61 ttatttcttt gattaaatat ctttcagaat ctaagccaga tgtctcaaaa aaattgattt
      121 ataatataat cattttttct gctattctta tttttccagt tttagtttca tattaaaata
      181 tacttttcat agacactgca ttctttcata ctcattttca catttaacta tacaagtagt
      241 cttactcatt tatgtactat actttattaa tatttattaa gaaaaactca aagatttaaa
      301 aatatatatt ttctataaag tatatttatg aattatttca tatcttcttt taaaataaca
      361 ttactaactt ctctatgttc atttctatac ttagttggag atatattata attcctttta
      421 aataagcgac taaaataatt tatgctatca aagccacatc tcatagcaat ttctgtcata
      481 tttaaatctg tttcctttaa ataatatata gctttatcaa gcctgattcc atttataaaa
      541 tcgattgtag tcttacctgt tatttgctta aatgttctac aaaagtgatg tgcactcaag
      601 ttcacacgac tagcaagttc ttttaatgta attttatcca tatatttttc ttctatcaaa
      661 tcaaagatac attcaaattt ttccaaagaa tactttcttt ttataaattc atcttcagaa
      721 tatattttat caatatgact tcttaataag agtactatta attgatagat attagctttt
      781 atagataact catatccaac ttctttattg tgatattcat caagtatagt tgtaatacat
      841 tttaaaatca gagaatcatt ttgaattaaa ttattaaata caatatgatt taaagccaat
      901 ggtgctaagt acttggtttg taacaaatca acttgattac taaaaaggaa tgtgggttca
      961 atacgaatac tatagaattt taaattatct gataagcttt ctaaataatg taattcatta
     1021 ctgtttgcta ttacaatatt tccaggcact accttaaaat tatccaatcc acattcaaga
     1081 tatgctatac catcaataaa ataatatatt tgtagatgct catgccaatg tcttttaaag
     1141 tttgctcctt ttttaatgtc atcctttaaa aaaatatcta taaagttttc ttgacctttc
     1201 ctgttaaaat atgtattttt atccttcatt attccccctt catcaaaata gtgctaatta
     1261 taagcaatat agttattgta ttcattattt catatcgcta ttatataaaa tgtaactatc
     1321 attgtaaaca ttaacataat gccagtcatt ataataagga ggtaataaaa atgacaaact
     1381 cttttaaaaa agatgataat agaaaaaaaa tcacagtttt atttgtagtc attgccatga
     1441 cttttatggc aacattagat tctagtatta taaatgttgc tctcccagtt cttgcaagca
     1501 aactaaatgt atctctagca tctattgaat gggtaatagc aagttactca attattattt
     1561 gttcaacact attatttttt ggaagacttg gagatattat tggtaaatca agagtatttc
     1621 aagtaggtac tattctcttt acatcagctt cattactatg tggattaagt aattctttaa
     1681 ctttacttat agtttgccgc tttattcaag gaataggcgc ttctgcctac atggcaaaca
     1741 atcatggaat tatcacagaa ctatttccaa aagaaagcag aggaaaagcc ctagggattt
     1801 tagttactgc agttgctatt ggaaatatgg ttggaccatc tgtgggagga tttattttgt
     1861 caatatttga ttggaatgtt atatttttta taaatattcc aatcggtctt attgtaatct
     1921 ttttaaatac aaaatttctt cctaatagta aaaaatcttc agaaaatatg gataaaactg
     1981 gtgctatact tcaattttta ggaacaacat tattttttag tgctctaatt agtgctcaac
     2041 aaacaggatt actaaatcca tatatattaa ttgcactatt attatcaatt atttttatta
     2101 tattattttt gatattagaa aaaaaacatc ctcaaccgct tcttgacctt gaaattttta
     2161 gaagttttaa attttcattg aatttaattt gtgctcttac atcattcatt tgtattgcat
     2221 catcaagtat tttaattcca ttttatttac aaagtactat gaaacttccc cctattcaag
     2281 caggtttatt tatgatacta tcacctttga ttttagccat tttttcacct atatttggga
     2341 atatatcaga taaaattaag tcagaaaaaa ttattttaat tggtcttctc gttatgagtt
     2401 ttggattctt tctaatgtca agattgaaag aaagttctgc ccttatttta tttgtaattt
     2461 atatatcgat aatatcaata ggacaagcta tatttcaacc tgctaacaat gctttgataa
     2521 tgtcaagctg ttctagaagt aagctaggag ttgtaggaag cataaattcc cttgtaagaa
     2581 atttaggaca agttataggt attactattt ctacaacact tttatataat tttatgagta
     2641 ttaaagctgg atatagggtc aatgattatg tgattaataa tgataaaata tttgtatttg
     2701 gaatgagaaa tgtttatatt attgttacac ttgtttgctt aataggtgca atattaattg
     2761 gcttttattt atttaaatat aataaaaatg aacaatagtt tttataatta tattcaaatt
     2821 atgattatat tataagaaat ttactaaaat acttcctttg agttaaattt aatttggaca
     2881 tattgactta aaaatgtttt attaatttga taaaatattt cttttcctat agtttataaa
     2941 taaaaatcag ctgagcaaaa tatttagtat attatgctca actgattcct ttattattta
     3001 actaaaactt caatattttc atcttttcca tctataacta tagtacatcc attatacaca
     3061 tctccagcaa taagtttctt tgcaattata gtttctaatg tatttcctat atatctctta
     3121 agaggtcttg ctccatatac agggtcatat ccttctctca ccataacatc ttttgctgaa
     3181 tttgtaactt caatagtaat atctttttct tttaatctat tttttaaatc tttcataaat
     3241 atatctataa ttttcttgat attttcttgg tctaaaggct taaacattat aatatcatct
     3301 actctgttta aaaactcagg tttaaatcta tgcttcattt cattcattac taaattgtta
     3361 gtagtctctg ttatatttcc tcctgcttct aatagataat tacttcctat attagaagtc
     3421 attattataa gagtattttt aaagtctact gtcttacctt tattatcagt aagtctacca
     3481 tcatctaata tctgtaagaa catgttaaat acatcctcat gtgctttttc tatctcatca
     3541 aatagtatta cagaataagg agcacgtcta actgcttctg taagttgacc accctcttca
     3601 tatcccacgt accctggagg aggtccaact agtcttgata cagcatgttt ttccatgtat
     3661 tcagacatat ctattcttat tatattatct tcactatcga ataaatttct agcaagagtt
     3721 tttgcaagtt cagttttacc aacacctgta gggcctaaga aaataaatga accaattggt
     3781 tttctttcat cttttaatcc tgctcttgca cgtattactg catttgaaac tgctgtaact
     3841 gcttcatctt gtccaataac tcttttatga agttcatctt ctagtttaag taatttttct
     3901 ctttctcctt caactagttt agttactggt atacctgtcc attttgatac aatgctagat
     3961 atttcttctt cagtaacttc ttcttttaaa agagaatttt cagaaccatc attcatattt
     4021 tcttcgtact gctttatttg ttcttctaac ttaggtattt caccatattt aacctctgct
     4081 gctttgttga aatcatattc tctttcatac ttttcagctt tacctttagc ttcgtctaat
     4141 tgagccttta agtttttaat atctaatatt tgactctttt ctttttcata ttttgctgtc
     4201 atttcatcat ttttagattt taactctgct atttcttttt gaatatcatc caatcttgat
     4261 ttacttttat catcattttc tttaagtaat gcttctcttt cagtttctaa tgtaaataac
     4321 tttcttctaa caacatctaa ttctgttggc aatgaatcta tttcactacg aatcatagct
     4381 ccagcttcat caattaaatc aattgcttta tctggtaaaa atctatcttg tatatatcta
     4441 tgagaaagtt ttgctgctgc tacaatagca ttatcatgta ttcttactcc atgatgtatc
     4501 tcaaatcttt cttttaaacc tctaagtata gatattgtat cttcaacagt aggttcttct
     4561 gcaattacag gctgaaaacg tctttcaaga gccttatctt tttctatata ctttctatat
     4621 tcatcaaaag tagttgcacc aatacagttc aattcacctc ttgcaagcat aggtttaata
     4681 agattacctg catccattga accttctgtt ttaccagctc caacaatagt atgaatctca
     4741 tctataaaca gtataatttt tccatcagaa ctttgaactt cttttaaaac tgcctttaat
     4801 ctttcttcaa attcacctct atattttgca ccagcaatta aagctcccat atcaagtgag
     4861 aatacaatct tatcttttaa accttctggg acatctcctc ttactattct ctctgctaac
     4921 ccttctacaa ttgcagtttt acctacacct ggctcaccaa tcaatacagg attatttttt
     4981 gttcttcttg ataaaattct tataatcctt cttatttctt catctctccc aattacaggg
     5041 tctaatttat ttttcttggc taaatctact aaatttgttc catatctagc aagtgcatca
     5101 tatgtgcctt ctgggtcttg tgtttctact ctttgactac ctctcacttg tgataaaata
     5161 tttaaaaagt cattcttatt tatattatat tgttttaata ttttaccaac agctgatttt
     5221 gattctgttt ccatcattgc aagcataaca tgctctacac ttatatatga atctttaaat
     5281 tctttagaaa tactctctgc ctttataagc acctcattta tttttctagt agctgatact
     5341 ccttgtgagt cagcaccttc tccatatact tttggaagct tatcaatttc aaagtttaca
     5401 gtatttctca aagaatcaat tgatatattc attttttcga ttatatttgg tatcaatcca
     5461 tcctcttgat taataagtgc tgagaaaaga tgaattacat ctacttgttg gttatgattt
     5521 tttactgctt cgttataagc ctcatttaaa cttttttgaa ctcttaaagt cattttttct
     5581 acgtccatat aaatccctcc attttaatat tatatccaaa taaattaaat tctctcattt
     5641 ataattattg attttctaag ctctaaaaga ctatcaagta aattctcgtt tttttgtata
     5701 tcgaaactca atgttaaatt aaatgttcca tctgaattaa aaaaatcgaa tacttctttt
     5761 gattttgcta ttaaatacaa gtcttcatct ataagtcttt tttcacctat taataaatac
     5821 tgacatttat ctataaaact ctttttaaaa tcaatagtgt atagattttc taaaatatta
     5881 tattgataaa tagcaatatt attaaacact tttaatatgt ttgaatttac aaaattgtaa
     5941 atttgattat tgttatacag tgatatttgt tcgtatatat attccctaaa taaaggatga
     6001 atgttttgct taagttttaa agtaacttca gctggtattt caaaataaag cttccagtac
     6061 ttagagttat ttttttctaa aataaaagct actttgttca aactggtaga actaatctcc
     6121 tttagtgtac aattaaaatt atagtgtctc aaactagttt tttcattctc aaatacatag
     6181 tcaaaccact gtagaacatt tctatcaagt tttaaactca tataaaaacc ttcttcctta
     6241 tttactaacc ttattaggtc tttttatctg attatattct gctaataaac tttctttatc
     6301 agctctacta cctttatata ctatatgtgg atttatcata tactcaccat ttttcactct
     6361 ttgtaaaaaa tccatttttt tcagctccgt aaacaatgaa gataaagaag tttttggata
     6421 ttcaaattca caagataatt catataatgt ttttctaatc ttattatttt tatccataga
     6481 gtttattaat tttaatggaa ttaaatcctt cttagtatac attccttcta ctactttaat
     6541 ataattctta aaacaaacat tcatatactt acttttattc ataactaaac ttttgctctc
     6601 tgtatattcc tgatttaaat ccttttttaa tgtcttatcc aaattaaata tctcttctca
     6661 ctctccttat ctctaattga taatataaat atattacaaa aaaatatgta tgtcaaaact
     6721 aaaaatgcaa aaagttcacc ttataagcaa acttttattt agctataagc taaactttat
     6781 tattttttta atttagtatt tccaatttat tggcaggatt tttgaacaat atttataaat
     6841 tttttaaaaa aatttaaatc tatttaatat ggcagacttt cataaaatac attacattta
     6901 ttaaatgtat aatattggca attagttttt tctaaaatca gttgacatat tatatatata
     6961 tttatataat gtgtatatac tatatataca atttaaggag gtgtcttatt gaatatagtt
     7021 attagtaatt cgagtgggaa gccaatatat gaacagatta ctacacaaat taaaagtatg
     7081 attataagtg gagagttacc agaaggctca gctcttccaa gtatgagact attggcaaaa
     7141 gaacttagaa taagtgtaat tactacaaaa cgagcatata gcgatttaga acgagacgga
     7201 tttattgaga cagttactgg taaaggcagt tttgtatcta gtaaaaacat ggattttgtc
     7261 aaagaagaac aatttcgttt aattgaagaa tacctacaaa aagcagttga tacagcaaaa
     7321 agtagtgata ttacatatga cgaattaaaa gatattttat ttttattata taaaggagaa
     7381 tgataagtat ggatgcaata actataaaaa atttaaataa aacttataaa gattttagcc
     7441 tacaagatat atctttttca gtaccaaaag ggagtgtaat gggatttgta ggtgaaaatg
     7501 gtgcaggaaa aacaactaca ttaaaagcaa ttttaaattt aatatcttat gatagtggaa
     7561 atatagaaat ctttggtctt gatagtaaaa aaaatgaaaa agaaattaaa gagcaaattg
     7621 gggttgtatt tgagggaagc aactttcatg aaaatttaaa cactgaccat gtttcaaaaa
     7681 tcatgagtaa aatctataaa aattggaatg acaccttatt taaagactac ttaaaaaaat
     7741 tgagagtacc agacaataaa ttaattaagg agttttcaaa ggggaataag atgaaactta
     7801 gtattgctgt agccttatct cataaaccaa aattattaat actagatgag gcaactagtt
     7861 cacttgaccc tatcgttcgt gaagaaatac tagatatatt tttagatttt atacaagatg
     7921 aagaacactc tattatctta tcttcacata ttacaagtga tttagataag atagcagact
     7981 atattacatt tatacataaa ggaaaaattg tatttagtga aaataaggat gaattaattg
     8041 atactatggg agttttaaaa tgtaaaccta gtgattttga taacctttca agagaggatt
     8101 attcatatta tcgtaaaagc caatttggat atgaagtact tcttaaagat aaacatagat
     8161 ttatctcaag acatccaaac tgtattgttg ataatacgtc tatagaagaa attatgttat
     8221 tttatgtgag aggtgataaa taatgaaagg tctaatttta aaagatttac ttaatttgaa
     8281 aggaaatata aagtttatac ttttattcat cattatgttt ggctttatgt cttctttagg
     8341 agatggaaat gttaataact ttataggtgt tattatagtt ttatgtacta caatgattgt
     8401 ttcaacattt tcatatgatg atttgaataa atgggatagt tatgtactta caatgcctat
     8461 taatcgcaat gatattgtat taagtaaata tttaactatg ttaatattta gctttatagg
     8521 tgttcttgtt tcacttattg ttagtgtaac tattggttat tttaaaaata cacttatatt
     8581 aaatgaaaca ctacttatta atgcactaat cttatcaatt tcagtatgtt ttggtagcct
     8641 tattctacca cttatttata aatttggtat agaaagagct cgtttattaa tgattttatg
     8701 ctttttagtt ccaacactag ctttattagt ttttaaaagt attttagaaa atattagttc
     8761 acctatttct atagaaatta tacttaatac actagtatat tctcttccat ttgttgctat
     8821 tttactattt gtgatttcat attttatatc atcaaaaatc tatagtaaaa aagaagtata
     8881 aaatatacta tatatatttc tgtatttaag tatttaaata aaatactatc gagtttattt
     8941 tggtagtatt ttatttttc
//
LOCUS       DAMJXI010000110         8909 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.117, whole genome shotgun sequence.
ACCESSION   DAMJXI010000110 DAMJXI010000000
VERSION     DAMJXI010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8909
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.117"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(70..678)
                     /locus_tag="PC465_003497"
     CDS             complement(70..678)
                     /locus_tag="PC465_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HDF2650767.1"
                     /translation="MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGV
                     NDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEP
                     ITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISD
                     FYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE"
     gene            complement(787..3525)
                     /locus_tag="PC465_003498"
     CDS             complement(787..3525)
                     /locus_tag="PC465_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HDF2650768.1"
                     /translation="MESKGTLSKNKVYILANGLFLVIALLNINLYTVSINMYRIILLW
                     IFGYSIVYISSFKTDEFINILKVGCLVLVFVSILGVVNLKIQKFQIVLLNLSIINMST
                     FIYLTISKVKKLRISPILIFYSAFVILDYFIRNIFSDINWNMIIILINICISMFNLLY
                     LLNKLDSNIEHYKLIKDLTYFVFFTTIICFVAISKINIVDSDRLIGVIYLLLCNHTYY
                     VYVYSLNNRVVYPYYELDSINKKLSKKSEQLGKINLAIEKDMIIQRTLKNYIDQRKEL
                     LRQALDTIPNVWIVTDYDFNISYTNNKFKDEFSKDMNNYYKILTFIKEDEKVAEKLKK
                     FDNDISIIDKLVELNDKIYLLSLSNNKDESNYLISLNDITNEIKIDEEIRNINKDYEN
                     IILNIPSPILVRSAEGGIKKNKVISINKKYEKSFKCVSSDLVDMTLEQYFETFNIDFF
                     DNREFKRLNLTQEKKAEIVSYNDTANCIVNFVMSDSEGEEHVEEVRVGDYWSDNKLFK
                     LLTFRDITKEINILRTVNEQKIIYEKLLDVIPEAIFLEDLSTSRVLYTNRAFRELFGI
                     SSDVLGVTTQKYRNILVKKYINNLNIGEREKSIHIVNENNHIKEVKMISRTLYFGQKR
                     SRVRIIKDLSVQRESERLKKALIKQRQYDQMKMEFYANISHELKTPLNNIYSSVQLIE
                     NLYKKGKIIDFQDILKEHIKITKQNMFRLLRLIDNIINISQVKSDIYKIKAVNFDIID
                     ITERIVTSISSYAKSKGIDLIFDTDEETVMVGLDPESIERIILNILSNAIKFTLEGGE
                     ILVGIYKKDETVEIIIKDTGVGIDKEKLNDIFNRFKQIENSGISNEFGSGIGLCLTKS
                     LIEIQNGKIYIDSKVGEGTNVKVIFPIKEVVEEVYDNSNYNDNIEKFEIEFFDIYK"
     gene            complement(3673..4464)
                     /locus_tag="PC465_003499"
     CDS             complement(3673..4464)
                     /locus_tag="PC465_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2650769.1"
                     /translation="MKLKKLLSVALVSAIAISAVGCSNKEDKKILVGASSNPHAKILE
                     VAKPLLKEKGYDLEVKIFDDYVLPNTALDEGSLDANFFQHIPFLEETVKEKGYKLTYT
                     SKVHIEPMGFYSEKVKSLDELKDGAVIAVPNDATNGARALKLLAKNKLIEVKDGELIT
                     KKDITKNPKNIVIKEMNAEQLPTVLKDVDGAVINSNYALTANLNPTKDAIVIESSDSP
                     YVNIIACRENNKDSDKIKALSEAMNSKEVKKFIQDEYKGSIVPAF"
     gene            complement(4500..5156)
                     /locus_tag="PC465_003500"
     CDS             complement(4500..5156)
                     /locus_tag="PC465_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2650770.1"
                     /translation="MNSLIDFLTTLFPNALLQTLYMVIVPTIVATILGFILAIILVVT
                     KPDGLKPNSTINSALGFIVNIFRSFPFMILIVAMIPITRLIVGTSIGETAAIVPITIG
                     AAPFIARIIESSLNEVDKGLIEAAKSFGATKRQIVFKVMIKEAMPSIVSGITLSIISI
                     LGYTAMAGAVGAGGLGNIALIYGYQRFDTAVMVYTVIALIILVQIIQGVGNLAYKKLK
                     "
     gene            complement(5149..6114)
                     /locus_tag="PC465_003501"
     CDS             complement(5149..6114)
                     /locus_tag="PC465_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HDF2650771.1"
                     /translation="MISIKNVNKYYGKIQVLKDVSIEIESGEIFGIIGHSGAGKSTLL
                     RCINGLEEYQEGSVLVSDKEVKSLNEKQMRDLRKELGMIFQHFSLLERKTVFDNVALP
                     LECFGYSKAEIKKRVLELLEVVGISEKKNDKPRNLSGGQKQRVAIARALALNPQVLLC
                     DEATSALDPNTTKSILSLLEDINKKLGITIIVVTHQMEVIKQICGRVAIMENGEVLEV
                     GDTEEIFLRNTKGLRKLIGEESIILPKGTNIKILFPKDISNEAIITTMARELNIDVSI
                     IFGKLEQFKDDILGSLIINISDKSGEQVKQYLTSKGIRWEEMINE"
     regulatory      complement(6220..6326)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(6616..7560)
                     /locus_tag="PC465_003502"
     CDS             complement(6616..7560)
                     /locus_tag="PC465_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HDF2650772.1"
                     /translation="MSRAERLIELMITINAKRSFTAGELAEEFSVSKRTILRDLQVLE
                     SIGFPLYSKVGAAGGYHVLKERILPPIAFSESEVKSIFFAYQSLEYYNDLPFEQETIS
                     VLKKFLNCIPNDIQYNIENIRRKFVFWTPDRHCSTPLLKELFNIVMNESTIKIEYSSK
                     QKNSVRTIVPIGLYAMNGLWYCPAYCIKSESIKEFRVDRIVKILSIENLSSKKYKVLS
                     SIHDYLKNMEVGTDYHIKINLTDEGVKRCETEFLLARGLKILSKGGYIDMYIPKSTLN
                     WVAEYFLTFGKNATIIEPIELKHLIKSKVLELYNHHCI"
     gene            7671..8138
                     /locus_tag="PC465_003503"
     CDS             7671..8138
                     /locus_tag="PC465_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650773.1"
                     /translation="MENNTIKADDIINYCLSNLDDVLLMNSWGERAIYYNPNGILKRG
                     VYVLTIKEKDSNHDKGSLVSRPNVYRVNIGLKKETFIEMFGYIPKRPGVGQIVDMDFD
                     FTKLDTIMPHPIYSWMGWICVLSPTEKTFENFKTLIGESYNFAKQKFKKRKNK"
     gene            complement(8308..8907)
                     /locus_tag="PC465_003504"
     CDS             complement(8308..8907)
                     /locus_tag="PC465_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650774.1"
                     /translation="MKLKRTLFVGLALVLAIGITACTKNNEKPSENTGKNPNESVNNN
                     EGYMNYYSTSYNDYIAGLNRYSIYDTPESINNQFKDKEYPGNEKYLSDVKAAYKDSRD
                     KIQSFVTSLKKDGKTEDTELKKMNDDLIAEGERLVKDIDKRIEKLDKVSDEDMKKGQN
                     DFIKLVHGTEDVGNDIGSGFRKMIKDMNDRLGITGNNKK"
BASE COUNT         2895 a         1484 c          861 g         3669 t
ORIGIN      
        1 ctataaaaaa ataagataca tacctataaa ataccttcct atagatacat atcttaccta
       61 tataaaaact tattctatat aaaaacgcca taaaaaatct tttgcttctt ctgcataatc
      121 tatatttata cgtttactag tttttatatc taactcatcc ttactaaata ctttttttcc
      181 tttatcatca taataaaaat cacttatata taattcttca cccattatac tcttactatt
      241 tagacttcta tctattttta aagctttgca aagttttcct ggtccgttag taatattttt
      301 tacttgatat ttactcaact cagtgtaagc tttgttgtat ctattcatag atatctcatc
      361 taaagaagtt ataggctcta cccctcttat taatacacac tctggcacat tttctatatt
      421 tgcagataaa ttcaagcaat tatacatacc ataaattaaa taaacatata tatgtccacc
      481 atctaaatat aatggcttag ttctatctgt ctttttattg ccatatacat gtgctccttt
      541 atcatttaca cccatgtatg cttctgtctc tatgattttg gtaacaatta ctttattttc
      601 atatttcctt attagatatt tacctaatat tgatttggct aaatcaattc cattttttct
      661 aaaaaaatcc ttttccaaaa tttcacctca taaaatttat ttaaaacgca tcaaatacaa
      721 ctaaagtaat aaataaaatt aactcttatt aatgtgatat atataaacaa taaatttaga
      781 catttattat ttatatatat caaaaaattc tatctcaaac ttttcaatat tatcattgta
      841 atttgaatta tcatatactt cttcaacaac ctctttaatt gggaatataa cttttacatt
      901 agttccttct cctaccttac tatctatgta aatcttccca ttttgaattt caatcaatga
      961 ttttgtaagg cataaaccta taccacttcc aaattcattt gatataccac tgttttcaat
     1021 ttgtttaaat cgattaaata tatcatttaa tttttctttg tctatgccca ctccagtatc
     1081 ttttataatt atctctactg tttcgtcttt tttatatata cctacaagga tttctcctcc
     1141 ttctaaagta aattttatag catttgataa tatatttagt attattcttt ctatcgattc
     1201 tgggtcaagc cctaccataa cagtttcttc atctgtatca aaaattaaat ctattccttt
     1261 agacttagca taactactaa tagatgtaac tattctttct gttatgtcaa taatatcaaa
     1321 attaactgct ttaatcttat atatgtctga cttaacttga gaaatattta ttatattatc
     1381 tattaatctc aataatctaa acatattttg tttagttatt tttatatgtt cttttagtat
     1441 atcctgaaaa tcaattattt ttcctttttt ataaaggttt tcaataagtt gaactgaact
     1501 atatatatta tttaaaggtg tcttaagttc atgagatata ttagcataaa actccatctt
     1561 catttggtca tactgtcttt gttttattaa tgctttttta agtctttcag actctctttg
     1621 cacacttaaa tctttaataa ttctcactct acttcttttc tgtccaaagt ataatgttct
     1681 tgatatcatt tttacttctt taatgtgatt attttcattt actatatgga tactcttctc
     1741 tctttctcct atatttaaat tgtttatgta tttttttact aatatatttc tatatttttg
     1801 tgttgtaact cctaatacat cactagaaat tccgaacaac tctctaaatg ctctatttgt
     1861 atatagtact cttgatgtac ttaaatcctc aagaaaaata gcctctggta taacatccag
     1921 taatttttca tatattattt tttgttcatt tactgttcta agaatattta tctctttagt
     1981 tatatctcta aatgtaagca atttaaagag tttattatct gaccaatagt ctccaactct
     2041 aacttcttca acatgctctt caccttctga gtcagacatc acaaaattaa ctatacagtt
     2101 tgctgtgtca ttgtaactta ctatttcagc tttcttttct tgtgttagat ttaatctttt
     2161 aaactcccta ttgtcaaaga aatctatgtt aaaagtttca aaatattgtt ctaatgtcat
     2221 atcgactaaa tcacttgaaa cacatttaaa actcttttca tattttttat ttatacttat
     2281 taccttattc ttctttatgc caccttcagc acttcttaca agtataggag atggaatatt
     2341 tagtataatg ttttcatagt ctttatttat atttcttatt tcttcatcta ttttgatttc
     2401 atttgtaata tcatttaaac ttattaagta attgctttca tctttattat tacttaaact
     2461 taacaaataa attttatcat ttaactctac cagtttatca attatactta tatcgttatc
     2521 aaatttcttc aatttttcag caactttttc atcttccttt ataaaagtta atattttata
     2581 ataattattc atatcctttg aaaattcatc tttaaattta ttatttgtgt aacttatatt
     2641 aaaatcatag tctgttacta tccatacatt tggtattgta tccagagctt gtctaagtaa
     2701 ttcttttctc tggtctatgt agttttttaa tgttctttgt ataatcatat ccttttctat
     2761 tgctaaattt atctttccta attgctctga ctttttactt aattttttat tgattgaatc
     2821 aagttcataa tatggataca ctactctatt attaagactg tatacatata cataataagt
     2881 atggttacat aatagtaaat atattactcc tattaatcta tctgaatcta ctatattaat
     2941 cttagaaatt gctacaaaac atataatagt tgtaaaaaaa acaaaatatg ttaaatcttt
     3001 tattaactta tagtgctcaa tgttactatc aagtttattc aacaaatata gtaaattaaa
     3061 catagatata caaatattaa ttaatataat aatcatattc cagttaatat cactaaaaat
     3121 atttcttata aagtaatcta atatcacaaa agcactataa aaaattagta ttgggcttat
     3181 tcttagtttt tttactttag aaatggttaa gtatataaaa gtagacatat taattatgct
     3241 taagttaagc aatacaattt ggaatttttg aatttttaaa tttactactc ctaaaatact
     3301 tacaaaaact aatacaagac accctacttt caatatattt ataaattcat ccgttttaaa
     3361 gctacttata taaactatag aatatccaaa tatccaaagt aaaattattc tatacatatt
     3421 tatagaaact gtatacaaat ttatatttaa aagtgcaata accaaaaata acccattagc
     3481 tagtatatag accttattct tacttaaagt tcctttagat tccatattcc ccaccacttc
     3541 ttcattttta tatagtttta cctataaata tgttaccaca attcttccaa aaaatttgtc
     3601 actttctagt tataaaaaaa aatgagtaaa tatttttaat tttactcatt ttgtagattt
     3661 tgtatattca gtttaaaaag ctggaactat acttccttta tattcatctt gtataaattt
     3721 tttaacttct ttactattca tagcctctga taaagcctta atcttatcac tatctttatt
     3781 attttctcta caagctatta tatttacata tggagaatca cttgattcta ttactattgc
     3841 atccttagta ggatttaagt tagctgttaa agcataatta gaatttatta ctgctccgtc
     3901 aacatctttt aatactgttg gtaattgctc tgcattcatt tcttttatta ctatattttt
     3961 aggattttta gttatatctt ttttagttat aagctctcca tcttttactt ctatcaattt
     4021 attttttgct aataatttaa gtgctctagc tccattagtt gcatcatttg gcacagctat
     4081 aacagctcca tcttttaatt catctaatga cttaactttt tctgaataga atcccattgg
     4141 ctctatatga actttagatg tataagtaag tttatatcct ttctccttca cagtttcctc
     4201 taaaaatgga atatgttgaa agaagttagc atccaaagac ccttcatcta aagctgtatt
     4261 tggaagtaca taatcatcaa atatttttac ttctaaatca tatccttttt cttttaacaa
     4321 aggttttgca acttccaata tctttgcatg tggatttgat gaagctccta ctagtatttt
     4381 tttatcctct ttgtttgaac aacctactgc tgatattgct attgctgaca ccaatgctac
     4441 tgataataat ttctttaatt tcatttttac tccccctctt taaaatgttt ataattaatt
     4501 tattttagtt tcttataagc cagatttcct actccctgga ttatctgaac taatattata
     4561 agtgctatta cagtatatac cattactgct gtatcaaatc tttgatatcc ataaataagt
     4621 gctatattac ctaatcctcc agctcctact gcacctgcca tagctgtata accaagtata
     4681 gatattattg ataatgtaat tccagatact attgaaggca tagcttcctt tatcataact
     4741 ttaaatacta tttgtctttt tgtagctcca aaagattttg ctgcttctat caatccttta
     4801 tcaacttcat ttaatgagct ttctataatt ctagcgataa acggtgctgc cccaatagtt
     4861 attggcacta ttgcagcagt ttcccctata cttgttccaa cgattaatct agttattgga
     4921 atcattgcaa ctataagtat cataaatggg aaacttctaa atatatttac tataaatcct
     4981 aatgcactat ttattgtgct atttggtttt aatccatctg gttttgtaac tactaatatg
     5041 attgctaata taaatcctaa tattgttgcc actatagttg gtactataac catatacaaa
     5101 gtttgtaaca atgcatttgg aaatagtgtt gttaaaaagt caattaaact attcatttat
     5161 catttcctcc catcttatgc ccttactagt tagatattgt tttacttgct ctccactttt
     5221 atctgaaatg tttataataa gtgaacctaa aatatcatct ttaaattgtt ctaatttccc
     5281 aaatattata gacacatcta tatttagttc tcttgccata gtcgtaataa tagcttcatt
     5341 agaaatatct ttagggaata gtatctttat atttgttcct tttggcaata ttatactttc
     5401 ttcacctatt aattttctaa gtcctttagt atttcttaag aatatttctt ctgtatctcc
     5461 tacctctaat acttctccat tttccattat tgctactctt ccacaaatct gctttataac
     5521 ttccatttga tgagttacaa ctattattgt tattcccaat tttttattta tatcttcaag
     5581 caatgaaaga attgactttg tagtatttgg gtctaatgct gaagtcgctt catcacaaag
     5641 aagtacttgt ggatttagtg ctaaagctct agcaattgca accctttgtt tttgtccgcc
     5701 acttagattt ctgggtttat catttttctt ttcagatatt ccaactactt ctaataactc
     5761 taaaactctt tttttaattt ctgcctttga gtatccaaaa cattctaatg gcaatgctac
     5821 attatcaaat acagtttttc tttcaagcaa tgaaaagtgt tgaaaaatca ttcctaactc
     5881 ttttcttaaa tctctcattt gcttttcatt caatgacttt acttctttat cagaaacaag
     5941 tacactgcct tcttggtatt cttctaatcc gtttatacat ctcagtagtg ttgatttccc
     6001 tgcaccacta tgacctatta ttccaaaaat ttctccagat tctatttcaa tacttacatc
     6061 tttaagcact tgaatctttc cataatactt attaacattt tttatgctaa tcataaaatt
     6121 tcctcccata tattctgctc agtttttatg tttatcctct cttatgtatt acaacaaaat
     6181 aaaagcccga gtataaactc aggcttagaa agctatttat actcatctat caactatatt
     6241 agttgcagga tttagcacca atgtatataa aatatactgg ttgccgggtt tcaaagggcc
     6301 agtccctcca ccactcttga taagacgtta tttaatttaa ttctattatc atttgttgct
     6361 atgttatata tgatatattc attaatagta tttgtcaata aatttattta aattttttat
     6421 tttttattat cgttaattaa ctatttttaa ttagttttct agctcctaac actttatatt
     6481 ttaatgtcta tataactata gaacatcatt ataagaaata aattaaataa catcaatcta
     6541 tctaaatcat ctgtaaagta aattaagaaa attaacattt tatccaaact ctatcctact
     6601 attaaataaa ataatttaaa tacaatgatg attatatagc tctagtactt tagactttat
     6661 caaatgttta agttctatag gttctattat tgtagcattt ttcccaaaag ttaaaaaata
     6721 ttcagccacc cagttaagtg tagattttgg tatatacata tctatgtatc cacctttaga
     6781 caagattttc aaccctcttg ccaacaaaaa ttctgtttca caacgtttta ctccctcatc
     6841 tgtcaaatta attttaatat gataatctgt acctacttcc atattcttaa gataatcatg
     6901 tatagaagat aaaaccttat atttcttact tgataagttt tctatactca aaatcttcac
     6961 aattctgtct acacgaaatt ccttaataga ttctgatttt atacagtaag ctggacaata
     7021 ccaaagtcca ttcatggcat acaaaccaat aggaacaatg gtacgtacac tatttttttg
     7081 ctttgatgaa tattcaattt taattgtaga ttcattcatt actatattaa acaattcttt
     7141 caataatggt gttgaacagt gcctatctgg tgtccaaaaa acaaatttac gccttatatt
     7201 ctcaatatta tattgaatat catttggtat acaatttaaa aattttttta aaacagaaat
     7261 agtttcttgc tcaaatggca aatcattata atattctagt gactgatatg caaagaatat
     7321 agattttacc tcactttctg aaaatgcaat cggtggaagt atacgctctt taagtacatg
     7381 atatccacca gccgctccaa cttttgaata taatggaaat ccaatactct ccagcacctg
     7441 taaatctctt agtatagtac gttttgatac agaaaattct tctgctaatt ctcctgctgt
     7501 aaaacttctt tttgcattta ttgttatcat cagttcaatt aaacgctcag ctcttgacat
     7561 atttatactc ctaatttaaa tatagtgaca ataattgtca ctattatatg ataagatatt
     7621 cttacattta aatcaataat aatagtaaag aaagaaggga ctgatacttt atggaaaata
     7681 atactattaa ggctgatgat attatcaatt attgtctatc aaacttagat gatgttttat
     7741 taatgaatag ttggggggaa cgagcaattt attacaatcc taatggtatt ttaaaacgag
     7801 gagtatatgt tcttaccatt aaagaaaaag acagtaatca tgataaaggt tcgttagtta
     7861 gtcgtccaaa tgtataccgt gtgaatatag gattaaaaaa agaaactttt attgaaatgt
     7921 ttggatatat tccaaagcgt ccaggtgtag gtcaaatagt tgatatggat tttgatttta
     7981 caaaattgga cacaatcatg ccacatccta tctactcatg gatgggatgg atatgcgtcc
     8041 taagccctac tgaaaagaca tttgagaact ttaaaacttt aataggagaa tcttacaatt
     8101 ttgcaaaaca aaaatttaaa aagagaaaaa acaagtaaaa acatatgaaa ataatcccta
     8161 aataaatcat aataaaaata ttaaggttac aagataaaaa ttaatatctt aataacatgc
     8221 aaaaaagcga agccaaaaaa tgtattattt ataaggcttc gctatatctc aaataattta
     8281 tttcaaattt caaaactatt tattctatta tttcttatta tttcctgtta ttcctaatct
     8341 atcattcata tcttttatca tttttctaaa accactacct atatcatttc caacatcttc
     8401 agttccatga actaatttta taaagtcatt ttgacctttt ttcatatctt catcagatac
     8461 cttatctaat ttttctattc tcttatctat atcttttact aatctttccc cttcagcgat
     8521 taggtcatca ttcattttct ttaactctgt atcttctgtt ttaccgtctt ttttaagaga
     8581 tgttacaaat gattgtattt tatctctact atctttatat gcagccttta catcacttag
     8641 atatttttca tttcctggat attctttatc tttaaactga ttatttatac tttctggagt
     8701 atcataaata gaatatctat ttagacctgc tatataatca ttatagcttg ttgaataata
     8761 attcatatat ccttcattat tatttacaga ttcattagga ttttttcctg tattttcact
     8821 tggtttttca ttatttttag tacatgcagt tatacctata gctaatacta gtgctaatcc
     8881 tacaaataaa gttcttttta atttcattt
//
LOCUS       DAMJXI010000111         8860 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.118, whole genome shotgun sequence.
ACCESSION   DAMJXI010000111 DAMJXI010000000
VERSION     DAMJXI010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8860
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.118"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            92..658
                     /locus_tag="PC465_003505"
     CDS             92..658
                     /locus_tag="PC465_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HDF2650775.1"
                     /translation="MRKLEEILEYNKSFVENKEYEQYVTSKHPNKKIVVLSCMDTRLT
                     ELLPKAMNLKNGDVKLIKNAGATIMHPFGSIMRSVLVAIYEFDVDEVMVVGHHGCGMC
                     NVDTDKLLGKILDRGISNDVILTLRSAGIDTKQWLHGFDSAEESVKDSIDLIKGHPLI
                     PDGIIVHGLIISPETGKLDVVVNGYEDK"
     gene            963..1424
                     /locus_tag="PC465_003506"
     CDS             963..1424
                     /locus_tag="PC465_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2650776.1"
                     /translation="MNSNSEEKLNDVFLQLMRIYFIRTHFYFDKLGLYHGQPQILFSL
                     KMKDGQSQKELADKRKVKASTTTVMIKRMEKAGLVERKQDEKDQRVSRIFLTDKGLEI
                     CNKVEEFNKELEREFFLGFSEEEKIVLRRLLMQVRDNLKAGCHKHEDEKYF"
     gene            1492..3738
                     /locus_tag="PC465_003507"
     CDS             1492..3738
                     /locus_tag="PC465_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011009877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2650777.1"
                     /translation="MFKLIKYLKKSALSIVIIVCLLVIQAVCDLSLPEYTSNIVNVGI
                     QQGGVENSVPSVIRESELNKITLFMDKSSKDKVLDNYTLLNKKDYVKYKDKYPGLKDE
                     SLYELNTKDKDTIDDLNVIFGKAILIVSGLEGDSKEVKAMKAQLMSKLPPQATQSGDV
                     DIFKLLSAMPKEQLDTLTKEMSKGFESMPESMITQSSVSYVRSEYEKIGIDTEKTQNN
                     YILFTGAKMLGIAMISMVATITVGFLAARVAASVGRNLRSGVFRKVMSFSNTEMNEFS
                     TASLITRSTNDIQQIQMLMVMLLRIVFYAPIMAIGGVIKVLNTNTSMAWIIAVAVVAI
                     LSLIVVLFSVVMPKFKLVQKLVDKLNLVSREIITGIPVIRAFSTEKHEEERFDKANKN
                     LTKTNLFVNRVMTCMMPAMMLIMNLITVLIVWRGAYSVDSGAMQVGDMMAFIQYTMQI
                     IMSFLMISMVSIMLPRASVSATRIDEVLVSDISIKDPEKSEAQEFKEDKKGLVEFKNV
                     SFMYPDAEEPILTNISFTAKPGETTAFIGSTGSGKSTLINLIPRFFDVTEGEILLGGV
                     NIKNVSQHDLREKIGYVPQKGVLFSGTIESNLKYGRKDATDEEMRTAAEIAQATEFID
                     SKPEAFKTEISQGGTNVSGGQKQRLSIARAIAKNPEVYIFDDSFSALDLKTDAALRKA
                     LKSKTAESTVLIVAQRISTILNAEQIIVLNEGEIVGIGTHKELLKNCEVYEQIALSQL
                     SKEELANE"
     gene            3731..5563
                     /locus_tag="PC465_003508"
     CDS             3731..5563
                     /locus_tag="PC465_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2650778.1"
                     /translation="MSRMGRGPMGKSMGAGQKANDFKGTMRKLIAYLSKFKISIILVI
                     VFAIGSASFSIVGPKILGKATTKIFEGLVSKVSGGNVGIDFNAIGKILTFLLFLYLIS
                     ALFSFIQGFIMSGISQKVSYNLRKEISAKLDRLPMKYFDTKTHGEILSRITNDIDTLN
                     QSLNQSMTQLITSVTTMIGVLIMMLSISGIMTLVAVLILPISMFVISRIIKKSQKYFR
                     YQQEYLGNVNGQVEETYSGQTIVKAFNREDEVIEEFDKLNDSLYNSAWKSQFLSGIMQ
                     PLMMFIGNLGYVMVSILGGWLAIKKTIEVGDIQSFIQYVRNFTQPMTQIAQVANLLQS
                     TAAASERVFEFLEEEEEVQIVENAVSIDGLEGKIDFENVNFGYNPNKTIINDFSVNVK
                     PGQKVAIVGPTGAGKTTIVKLLMRFYDVNSGSILIDGHNIKDFNRSELREMFGMVLQD
                     TWLFSGSIMENIRYGKLNATDEEVIEAAKSAHVHRFIKTLPDGYKMKLNEETSNVSQG
                     QKQLLTIARAILADPKILILDEATSSVDTRTEVLIQKAMDNLMEGRTSFVIAHRLSTI
                     RDADMILVMNEGDIVEQGNHEELLKKGGFYANLYNSQFEEDEAM"
     gene            6282..7559
                     /gene="hflX"
                     /locus_tag="PC465_003509"
     CDS             6282..7559
                     /gene="hflX"
                     /locus_tag="PC465_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDF2650779.1"
                     /translation="MDMAKKGITVGLNINNKSEDFNELMIELENLCSACDIDVVGSIT
                     QNAKQVNRAFYIGTGKVEEILNLIKKENIEIVIFYNELSTSQLKNLEEKLNCEIIDRT
                     ALILDIFAQRAKTREAKLQVEVASLKYMLPRLIGSNENLGRQSGGVGTKNRGSGEKKL
                     ELDRRRIEEKITSLNRELDDLKFQRETQRSMRRKSNLPNVALVGYTNAGKSSIMNKLV
                     DIFKNSEEKKVFEKNMLFATLETSVRNIVLANNKEFLLSDTVGFVSNLPHDLVKAFRS
                     TLEEACEADVLLHVIDISNPSYKSHIKVTEDTLKQIGADGIPMIHVYNKIDLIDVEVL
                     DRILDSIDKEGIFVSVKKDINIDKMIKCICDSIFKDYVRCKFLIPYDKGHVVSYFNEN
                     TSIINTEYREDGAILDVECSNIEYNKYKKYALE"
     gene            7792..8289
                     /locus_tag="PC465_003510"
     CDS             7792..8289
                     /locus_tag="PC465_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2650780.1"
                     /translation="MDAESLMKKYMVDDDSRKQAIFASIFVMQNKLQTTCDKLDPELT
                     MKQWLLLAIADSVDETLTLTKLGELMGCSRQNVKKLAIALEKKGFIEIEQNEKDSRAI
                     CLVTKDRVEEYSKKVRGMQEKVLQLLFEDFTEKEVEQLFFGIMKLSIGIENVKNYVEN
                     NDVGE"
     gene            8339..>8860
                     /locus_tag="PC465_003511"
     CDS             8339..>8860
                     /locus_tag="PC465_003511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDF2650781.1"
                     /translation="MKNVVVIYKSKYGSTKKYAKWLSELLSCDIFETKNINIEKVMKY
                     DTIILGGGLYACNIAGISFLKKNYKELQKKNLVVFGVGAAPYDDEVIKKLREVNFKDE
                     LNKIPCFYCRGAWDETKMSFIDYTLCSFFKKSIAKKERQGLKPAEAPLLSGEAFDWCN
                     KENLTPILDYIREL"
BASE COUNT         3514 a          892 c         1609 g         2845 t
ORIGIN      
        1 ttaataaata taaattaaat tatatgtgta tatattgtac tttaatagtg atataataat
       61 aaaaaaattt ttaaagaggg tgatattaca tatgagaaaa cttgaagaga tattagaata
      121 taataaatca tttgtagaga acaaagaata tgaacaatat gtgacatcaa aacatccaaa
      181 taaaaaaata gtagtcttat cttgtatgga tacaagatta actgagcttt tgcctaaggc
      241 tatgaatttg aaaaatggag atgtgaaact aataaaaaat gcaggagcta ctataatgca
      301 tccttttgga agtattatga gaagtgtttt agttgcaatt tacgaatttg atgtagatga
      361 ggttatggtt gtagggcatc atggatgtgg tatgtgtaat gttgatacgg ataagttact
      421 tggtaaaatt ttagatagag gaatatctaa tgatgtaata cttacacttc gtagtgctgg
      481 aattgataca aaacaatggt tacatggatt cgattctgca gaagaatctg taaaagatag
      541 tattgattta ataaaagggc atcctttaat tccagatggt attattgtac atggtctaat
      601 tatatcacct gaaactggga agttagatgt tgttgtaaat ggatatgaag ataagtagag
      661 tatcataatg ttatataatc aagatactgt tgaatatgat gttgtttcaa aatttatttt
      721 gggacaactt ttttatttaa aaatatatga aaaggtttat tttaagcttt acaataaaaa
      781 atataagtag ctgactaatt aaaaatctta ctattattta ttaaaattat aactatatga
      841 tataaaaata tttaataaat gaaatttata tgaatttttt ataaatatat tgaaaaaatg
      901 catgcagtat agtaaaataa tacttagctg actaagtaat ataaaaaata aggagggcaa
      961 gtatgaatag caattctgaa gaaaaattaa atgatgtttt cttgcaatta atgcgaatat
     1021 attttataag aactcatttt tattttgata aattaggctt atatcatggt caaccccaaa
     1081 tacttttttc tttaaagatg aaagatgggc aaagtcaaaa agaattagca gataaaagga
     1141 aagtaaaagc atctacaact acagttatga taaagaggat ggaaaaagct ggacttgtgg
     1201 aaagaaaaca agatgaaaag gaccaaagag tatctaggat ttttttgaca gacaaaggtt
     1261 tagaaatatg taataaagtt gaagaattta acaaggaatt ggaaagagag ttttttttag
     1321 gatttagtga agaagaaaaa atagtactta gaagacttct aatgcaagta cgagataatt
     1381 taaaagcagg atgtcataag catgaagatg aaaaatattt ttaaagttta aaataatgtt
     1441 tttcaattta atgttattag actaattaat attacagaag ggaagaaatg tatgtttaaa
     1501 ttaattaaat atttaaagaa atcggcatta tcaatagtaa taatagtctg tctattggta
     1561 attcaagcgg tatgtgacct ttctttacca gaatacacat ccaatatagt aaatgtaggt
     1621 atacaacaag gtggagtaga aaactctgtt ccatctgtga ttagagagag tgaattaaat
     1681 aaaattactt tatttatgga taaaagtagt aaggataaag tactagataa ttatactttg
     1741 ctgaataaaa aggattatgt taagtataaa gataagtacc caggtctaaa agatgaatct
     1801 ctttatgagt taaatactaa agacaaagac actatagatg atttaaatgt tatttttggt
     1861 aaagctattt taatagtatc agggcttgag ggcgatagta aagaggtaaa agctatgaaa
     1921 gctcagttaa tgagtaaact tccaccacaa gctactcaaa gtggagatgt tgatatattt
     1981 aaattgttat cagcaatgcc aaaggaacag ttagatacat tgactaaaga gatgagcaaa
     2041 ggctttgaaa gtatgccaga gagtatgata acacaaagct ctgtttcata tgtaaggtca
     2101 gaatatgaga aaataggtat tgatacagaa aaaactcaaa ataattatat attatttact
     2161 ggtgctaaaa tgcttggtat agcaatgatt agtatggtag ctacaataac agtaggattt
     2221 ttagcagcaa gagtagccgc aagtgtaggt agaaatttaa gaagtggagt atttagaaaa
     2281 gttatgtcat tttcaaatac tgaaatgaat gaattttcta cagcttcatt aattactcgt
     2341 agtacaaatg atattcaaca gatacaaatg ttgatggtta tgttgcttag aatagtattc
     2401 tatgcaccta taatggctat aggtggagtg ataaaggttt taaacacaaa tacttcaatg
     2461 gcctggatta tagcagtagc agtagttgct atcttatcat taattgtagt gttattctca
     2521 gtggttatgc ctaagtttaa actggttcaa aagcttgttg ataagttaaa cttagtaagc
     2581 cgtgaaataa ttactggtat tccagttatc agagctttta gtactgaaaa acatgaagaa
     2641 gaaagatttg ataaagcaaa taaaaattta actaaaacaa atctttttgt aaatagagtt
     2701 atgacatgta tgatgcctgc tatgatgctt ataatgaacc ttatcacagt tcttatagtt
     2761 tggagaggtg catacagtgt tgattctgga gcaatgcaag ttggagatat gatggcattt
     2821 atacaatata caatgcaaat aataatgtca ttcttaatga tatcaatggt atctattatg
     2881 cttccaagag catccgtttc agctacacgt atagatgaag tattagtgtc agatataagc
     2941 ataaaagacc cagaaaaatc agaggcacaa gagtttaagg aagataaaaa gggtcttgtt
     3001 gaatttaaaa atgtttcgtt catgtatcca gacgcagaag aacctatatt aacaaatata
     3061 tcttttacag caaagccagg agaaacaact gcctttatag gaagtactgg tagtggtaag
     3121 tcaactctta taaatttaat tcctcgtttc tttgatgtta ctgaaggaga aatattactt
     3181 ggtggagtta atataaaaaa tgtttctcaa catgatttaa gggaaaaaat tggatatgta
     3241 cctcaaaagg gagtattgtt ttctggtact atagaatcca acttaaaata tggtagaaaa
     3301 gacgcaacag atgaagaaat gagaacagca gctgaaatag ctcaagctac agaatttata
     3361 gattctaaac cggaagcttt taaaactgaa atttctcaag gtggaacaaa tgtatctgga
     3421 ggtcaaaaac aaagactttc tattgcaaga gcaatagcaa aaaatccaga agtttatata
     3481 tttgatgata gtttttcagc acttgactta aaaactgatg cagctcttcg taaggcttta
     3541 aaatcaaaaa ctgctgaaag tacagttcta atagttgcac aaagaattag tactatctta
     3601 aatgcagaac agataattgt tttaaatgag ggagaaatag ttggaatagg aacacataaa
     3661 gagcttctaa aaaattgcga agtttatgag caaatagctt tatcacaact ttcaaaggag
     3721 gagctagcta atgagtagaa tgggaagagg tcctatggga aaatctatgg gagcaggaca
     3781 aaaagcaaat gactttaaag ggactatgcg aaaactaatt gcatatttat ctaaatttaa
     3841 aatatcaata attctagtaa ttgtatttgc tattggtagt gcgtcgtttt ctatagtagg
     3901 tccaaaaatt ttaggaaagg caactacaaa gatatttgaa gggctagtga gtaaagtttc
     3961 tggaggaaac gtaggtatag attttaatgc aattggaaaa atcttaacct ttttactttt
     4021 cctttatttg ataagtgcac tgttctcttt tatacaagga tttataatga gtggaatttc
     4081 tcaaaaagta tcctataatt taagaaaaga gatttcagca aaattggata gattgccaat
     4141 gaagtatttt gatactaaga cacatggtga aatattatcg agaattacga atgatataga
     4201 tactttaaat caaagtttaa atcaaagtat gacacagctt ataacatcag taacaactat
     4261 gataggtgtt ttgataatga tgttatctat aagtggaatt atgacattag tggcagtttt
     4321 aatattacca atatcaatgt ttgtaatttc aagaataata aagaaatcac aaaaatactt
     4381 tagatatcaa caagaatatt taggaaatgt aaatggtcaa gttgaagaaa cttacagtgg
     4441 ccaaacaata gtaaaagcat ttaatcgtga agatgaagta attgaggagt ttgataaatt
     4501 aaatgatagc ctgtataatt cagcgtggaa atctcaattt ttatcaggta taatgcaacc
     4561 acttatgatg tttattggaa acttgggata tgtaatggta tcaatcttag gaggttggct
     4621 tgcaattaag aaaacaattg aggttggtga catacagtca tttatacaat atgtaagaaa
     4681 ctttacacag ccaatgactc agattgcaca ggttgccaat ttattgcaat caacagcagc
     4741 agcttctgaa agagtatttg agtttttaga agaggaagaa gaagtccaaa ttgttgaaaa
     4801 tgcagtttca atagatggtt tagaaggtaa aattgatttt gaaaatgtca actttggata
     4861 taacccaaac aagactataa taaatgattt ctcagtaaat gttaaacctg gtcaaaaagt
     4921 tgctattgtt ggacctacag gagcaggtaa aactacaata gttaaactgt taatgagatt
     4981 ttatgatgtt aatagcggtt caatactgat tgatggtcat aatattaaag attttaatcg
     5041 tagtgagctt agagaaatgt ttggtatggt tcttcaagat acatggttat ttagtggttc
     5101 aattatggaa aatataagat atggtaagtt gaatgctaca gatgaagaag ttatagaggc
     5161 tgctaaatct gcacatgttc atagatttat taagacatta ccagatggat ataagatgaa
     5221 attaaatgaa gaaacaagta atgtttctca aggtcaaaaa caattattga ctatagctcg
     5281 tgctatttta gctgatccta aaattttaat attagatgaa gctacaagtt ctgtcgatac
     5341 tagaacagaa gtattgattc aaaaagctat ggataatctt atggaaggta gaacaagttt
     5401 tgttatagcc cacagattat caactatacg tgatgctgat atgattcttg taatgaatga
     5461 aggagatata gttgaacaag gaaatcatga ggaacttcta aagaaaggcg gattctatgc
     5521 caatctttac aattctcaat ttgaagaaga tgaagcaatg taacaaaaaa ctatcttagc
     5581 atagacatgt aattaataag ataaaataaa tgagggtgcc ttaaaatgaa ctttttaatt
     5641 cataaggcac tcttttgtgt atgaaataaa atgtattttt atcattttaa caatgaaaaa
     5701 gaggattctc tatattttga gatagccaca taattttatg tctttacaaa gtgtttattt
     5761 tattataata tgtagtaagg aaaatgttgg aggtgattat caaaatgtat atttaatttt
     5821 attctttaaa ttttattata aatagaattt aattttaata gttgatgatt atattgaagt
     5881 atatgttttt attactttta ttaatcatgc aaataactac ttaaatttaa gaatagggtt
     5941 aaatataaaa tgataattac atataagtta attaaactaa tgtattttta atatatattt
     6001 agaattttaa tccttcttat gatataagta gcttgttttg tattacttag atttgtaagg
     6061 agttttttta ttgaaaaaac tgcataatat atttgggagg aggtgtaaga aagtgatttt
     6121 ttatataaga ttgagaaaat aatgcacgat tatggttatt ataatagtaa ataagaagtg
     6181 tcatttaagg ataagataaa aagcaaaatt cttgatgaat ttaattatag agccataatc
     6241 tcgtgctata gattaaataa aaaatagcag ataaggagaa tatggatatg gcgaaaaaag
     6301 gaataacagt aggattaaac ataaataata aatctgagga ctttaatgaa ctaatgattg
     6361 aacttgaaaa cttatgttca gcatgtgata ttgatgttgt agggagtata actcaaaatg
     6421 caaagcaggt taatagagca ttttacattg ggacaggtaa agttgaggaa atattaaact
     6481 taataaagaa agaaaatata gagatagtta tattttacaa tgaactttct acatcacaac
     6541 taaaaaatct tgaagaaaag cttaattgtg aaattataga tagaacggca ttgatacttg
     6601 atatatttgc acaaagggca aaaactagag aagctaaact tcaagtagaa gtagcaagtt
     6661 taaaatatat gttaccaaga cttataggtt caaatgaaaa tttaggacgt caaagtggtg
     6721 gagttggtac taaaaataga ggttctggtg agaaaaaatt agaacttgac cgtagaagaa
     6781 tagaagaaaa gataacatct ttaaataggg agttggatga tttaaaattc caaagagaaa
     6841 ctcaaagaag tatgagaaga aaatcaaatc ttccaaatgt agctctagtc gggtatacaa
     6901 atgctggtaa atcttcaata atgaataaac tagtagatat atttaaaaac tctgaagaaa
     6961 agaaagtgtt tgagaaaaac atgttatttg ctacacttga aacttctgtc agaaatatag
     7021 ttcttgcaaa taacaaagaa tttttattat ctgatactgt tggttttgta agtaatctac
     7081 cacatgactt agtaaaagca tttaggtcaa cattagaaga agcatgtgag gcagacgtac
     7141 tgttacatgt tattgatatt tcaaatccaa gctataaaag tcatattaaa gtgacagaag
     7201 atactttaaa acaaataggt gcagatggta tacctatgat acatgtgtat aataaaattg
     7261 atttaataga tgtagaagta ttggatagaa ttttagatag tatcgataaa gaaggtatat
     7321 ttgtttcagt taaaaaagat ataaatatag ataaaatgat aaaatgtatt tgtgatagca
     7381 tatttaaaga ttatgtaaga tgtaagttct taattccata tgataaaggt catgtagttt
     7441 cttattttaa cgaaaatacg agcattataa atacagaata cagagaagat ggagctattt
     7501 tagatgtaga atgtagcaat atagaatata ataagtataa aaagtatgct ttagagtaaa
     7561 ttttgaaaaa cttattatag cctaaaatat atttaattta taatttatta taaattgatt
     7621 gtaaatatga ttttatgaaa cggtatagcc ataatgctat gccgttttgc catttataat
     7681 aaaaataaat ttattgacac aatagtaact aattactata atataaagta actaattact
     7741 atttaaaatt atcaaaaaat taaaatctaa gataaagaga agtgtataat aatggatgca
     7801 gaaagtttaa tgaaaaaata tatggtagat gatgatagta gaaaacaagc tatatttgca
     7861 agtatatttg taatgcaaaa taaacttcaa actacatgtg ataaattaga cccagaatta
     7921 acaatgaaac aatggttact tttagctatt gcggactctg tagatgaaac tcttacatta
     7981 accaaacttg gagaattaat ggggtgttca agacaaaatg taaaaaaact agctattgct
     8041 ttagaaaaga aaggttttat agaaattgag caaaatgaaa aagattcaag agctatctgt
     8101 cttgtgacaa aagatagagt ggaagagtat tctaaaaaag taagaggtat gcaggaaaaa
     8161 gtattacagc ttttatttga agattttaca gagaaagaag tggaacagtt attttttgga
     8221 attatgaaat taagtatagg aattgaaaat gtgaaaaatt atgtagaaaa taatgacgtt
     8281 ggagaataag caagtatcaa atcaactttg tatgacatca gagagggggg taatttatat
     8341 gaaaaatgta gtagtgattt ataagagtaa gtatggttca acaaaaaaat atgctaaatg
     8401 gctttcagaa ttattgtctt gtgatatttt tgaaactaag aatattaata tagaaaaggt
     8461 tatgaagtat gatacgatta ttttaggagg aggtctttat gcttgtaata tagcgggaat
     8521 ttctttctta aaaaaaaatt ataaagaatt gcagaaaaaa aatttagtag tatttggcgt
     8581 aggagctgct ccatatgatg atgaagtaat aaagaaatta agagaagtaa attttaagga
     8641 tgaattaaac aaaattcctt gcttttattg tcgtggggca tgggatgaga caaaaatgtc
     8701 ttttatagat tatactcttt gtagtttttt taaaaaatct atagctaaaa aagaacgtca
     8761 aggtcttaaa ccagcagaag cacctttatt gtctggagaa gcatttgatt ggtgtaataa
     8821 agaaaattta actccaatac ttgattatat aagagaactt
//
LOCUS       DAMJXI010000112         8575 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.119, whole genome shotgun sequence.
ACCESSION   DAMJXI010000112 DAMJXI010000000
VERSION     DAMJXI010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8575
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.119"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            237..1223
                     /locus_tag="PC465_003512"
     CDS             237..1223
                     /locus_tag="PC465_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2650782.1"
                     /translation="MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEY
                     GYEPNAFAQSLRAKKTYFIGIITPCLDSFVKSKIMMAIDEELKELKYTSLIINTNRKI
                     RSEIDSISKLASLKVDGIILIGTEITKEHKNEIEKLDIPIVVVGQKVDGINSIVNDDY
                     GAGYKMGQYIANKGYKNIVYLGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQ
                     ETSIQRSGEMLESENPDIIICATDNIAIATMKEINKRGKSIPQDISVAGFGGYDVLSI
                     ISPKLTTIKFENKNAGKVAANTIVNLIQERKEPLLKEIKFELIEGESTINKN"
     gene            1392..1540
                     /locus_tag="PC465_003513"
                     /pseudo
     CDS             1392..1540
                     /locus_tag="PC465_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423822.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIB"
     gene            1559..3040
                     /locus_tag="PC465_003514"
     CDS             1559..3040
                     /locus_tag="PC465_003514"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HDF2650783.1"
                     /translation="MYKEPKYRTILESTKEELNKLRNISLNDKYKPLFHIHPQHGLLN
                     DPNGLAYYNGKYHVFYQWYPYDATHGMKHWAYVSSDDFVNWNREDVALIPIESYESHG
                     AYSGNAIEVDGKLHMYYTGNIKYSAEDRYAYQNLAIMNKDGKITKYENNPIVSEIPKG
                     YTGHVRDPKVFKRKDKYFMLLGAQTSDKKGVIIVYESKNSIDWNFKGELNVKNIDEDF
                     GYMWECPDYINIDEKDILIFSPQGVEPKGFDYQNIYNVVYAIGNMDLDNLTFEIDTMK
                     ELEKGFDFYAPQTFIKDSQIILFAWAGMGEVLYPTDKNKWAHCLTVPRKLNIKNNKLL
                     QMPVDELIKLRYDETSGQNTIKNNINIIENNENLYELNINIKNIDSNKFGLELFSSQD
                     EGVKLEFNKLGNIVTLDRSNFKKVFGVEYGTNRKEYINIDENTNIKVLADRSILEIFI
                     NDGEVVFTSRIFAKENSNQIRVYSDKIVEYEYTKFKLKQGIEL"
     gene            3066..4037
                     /locus_tag="PC465_003515"
     CDS             3066..4037
                     /locus_tag="PC465_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HDF2650784.1"
                     /translation="MKKVISIGEALIDFIPNQNGGKLKNVSEFRRVAGGAPANVSAVV
                     AKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYVLRTSKANTGLAFVSLKEDGNRD
                     FSFYRNPSADMLLEADEVKKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSI
                     ISFDPNIRLPLWDSEQSCKKAISEFLPFAHIVKISDEELEFITGENDIEKSLHKLFVG
                     NVELVLYTKGKDGVDAYTKKVKGMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLN
                     DIKEMKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEITEFIKNL"
     gene            complement(4293..4895)
                     /locus_tag="PC465_003516"
     CDS             complement(4293..4895)
                     /locus_tag="PC465_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2650785.1"
                     /translation="MEVCILMGSPKKKGNTAAILKPFIEELENYNSNIEVIWLYDCKI
                     EPCIACKKCQDNLFDFGCYCKDDVQKIFKKILMCDLIVFATPIYSWYCTSPMKALLDR
                     LVYGMNKYYGNEKGPALWAGKPVALITTCGYRPEKGADIWENGMKRYCKHSQLKYIGM
                     LVERDLGKPNFMNKEKEEDSRQFAKQIYYILDNSIEVDNC"
     gene            5176..6387
                     /locus_tag="PC465_003517"
     CDS             5176..6387
                     /locus_tag="PC465_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HDF2650786.1"
                     /translation="MYSNEDYKFIEENAPCYIYDETNIIEKCKELKNNILGFDFLYSI
                     KTNPYNKIVKSIAEQGFGADASSTNEVMISSKCGVSKDDIYYSSPGKTEIDIETVLDK
                     CIIIADSITEIELINKISKKHNQKVKIGIRINPDFTMDDDSAKSSKFGIDIEDMSSVF
                     KMLSMCDYVSVVGIHIHIKSQVLDFEKLGHYYEKCFFIALNLNKSKYINIEFINFGSG
                     LGVAYDNLRENPLNLKELSKLTQKIAFTNSNTLKSRLLIESGRFIVCKSGNYYVKIVD
                     IKVSRGKKYLIVKNGLNGFMRPIISNLIENITCGVELEGQEPLYTSNHAFSLSVLNNL
                     KEEEYVNVVGNLCTSLDVIANNIKLKKANIGDLISISNAGSYSYSLSPLLFSSYEFPK
                     QYYKRKDGYIE"
     gene            6455..6652
                     /locus_tag="PC465_003518"
     CDS             6455..6652
                     /locus_tag="PC465_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HDF2650787.1"
                     /translation="MELWKRNLFVCWIGMFFSSIGMSQIAPILPLYIKQLGVTDVSLI
                     QQYSGIIFGCTFVVAAIFSPI"
     gene            6686..7657
                     /locus_tag="PC465_003519"
     CDS             6686..7657
                     /locus_tag="PC465_003519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2650788.1"
                     /translation="MLLRASIGMGIVIFTMAFVQNVYQLLGLRILQGVFTGYATACTT
                     LIATQTDKNHSGWALGTLATASTTGSLIGPTVGGYIESILGLKSTFIITGGLLFVSFI
                     ISILFVVDNFKPKEIKESISIPKEQLNILPNKFLIASIFVTTFITQLALYSIEPIVTI
                     YISQLTNFASNVALIAGLTFSASGLANLLAAQKLGKMSDKIGPQKVLLISLLWAGIIF
                     IPQAFVKTAWQLMLLRFLLGLSVAGLNPSVNSLLKKIAPEEYVGKIFGYNASAQYIGC
                     SSGAFLGGQISAHLGIRTVFFSTSLLLFMNALWMYKFTGLFIKDKTK"
     gene            7844..8221
                     /locus_tag="PC465_003520"
     CDS             7844..8221
                     /locus_tag="PC465_003520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2650789.1"
                     /translation="MTISKIPQAELKVMKFIWEKNDTVTSKETIEAMERKYGWKQTTT
                     LTLLSRLVKKHFLSAEKIDRYTHYTIVVGHKEYLSVETKDFLSNIHDNSLQSLISALH
                     DDEVVDKDMLDLFESHFKNLEEE"
BASE COUNT         3490 a          899 c         1359 g         2827 t
ORIGIN      
        1 ttatattata aataaattag agtatttatc aattcatagt agataaaatt gaaattaaat
       61 ataacaacaa aaaatgaaaa ttacaattaa tttaatgtta aagactcaat tatttggatg
      121 tggaatggat agtacaagta gtatataaaa agtattgact ggacaaataa ctatatttta
      181 ttttaaatat ataatataat gtaataaaat atatcaaatg tagaaggtga taacctatga
      241 aaaaaataac aataaatgat attgctaact tggcaggagt atctaaaagt actgtatcaa
      301 gatatctaaa caataaagat atcagtgatt ctactaaaga gaaaataaag acaataatag
      361 atgaatatgg atatgagccg aatgcatttg ctcaaagttt gagagctaaa aaaacatact
      421 ttattggtat tataacaccg tgtttagatt cttttgtaaa atctaaaatt atgatggcaa
      481 tagatgaaga actcaaagaa ttaaaatata catcactaat tattaatact aatagaaaaa
      541 taaggtcaga aatagatagt atatcaaagt tagctagtct aaaagttgat ggaataatac
      601 taattggtac cgaaataact aaagaacata agaatgaaat tgaaaagtta gatataccga
      661 tagttgtagt tggacaaaaa gttgatggta tcaatagcat agtgaatgat gattatggag
      721 caggatataa aatgggtcaa tatattgcta ataaaggtta caaaaacatt gtatatttag
      781 gtgttgatga aagtgatata tcagttggtt taaatagaaa aaatggagta cttaatgggt
      841 taaaagataa agggtatgat gcaaaagtat tttatactga ctttgaccaa gaaacgtcta
      901 tacaaagaag tggagaaatg ctagaaagtg aaaatccaga tataataata tgtgcaactg
      961 ataatatagc aatagcaaca atgaaagaaa tcaataagag aggtaaaagt ataccacaag
     1021 atatatctgt agctggattt gggggatatg atgtattgtc tattataagc cctaaactta
     1081 caacaataaa gtttgaaaat aaaaatgcag gtaaagtagc agcaaatacg atagtaaact
     1141 taatacaaga aagaaaagaa ccactattaa aggagattaa atttgaatta atagaaggtg
     1201 aaagtacaat aaataaaaat taagatacac attacatata ttagtaatgt gtattttttt
     1261 actaaaaaaa ctataattct aaaaattagg aaaacttttt tgaaagaaat attgcatctg
     1321 aaataaattt atgctaatct ttaattaaac cggtttcgaa accggtttaa ttaaaccgat
     1381 agaatagcaa aatgagtgca aaaataactg attgtaacaa agtatcaaag taattattgg
     1441 agtacatagg aataaacaaa atataaaaga tgtagcacat tgtgtaataa gactaagaat
     1501 tgttttagat agcaataata aagcaaatat aaaattataa aagaaaagga ataaaaatat
     1561 gtacaaagag cctaaatata gaaccatatt agaatcgaca aaagaagaat taaataaatt
     1621 aagaaatata tctttaaatg ataaatataa accactattt catatacatc cacaacatgg
     1681 actacttaat gacccaaatg gattagcata ttataatggt aagtatcatg tattttatca
     1741 atggtatcca tatgatgcaa ctcatggaat gaagcattgg gcttatgtaa gttctgatga
     1801 ttttgtaaac tggaatagag aagatgtagc attaatacca atcgaaagtt atgaatctca
     1861 tggagcatat tcaggtaatg cgatagaggt agatggaaaa ttgcatatgt attatacagg
     1921 gaatataaaa tatagtgcag aagatagata tgcatatcaa aacttagcta taatgaacaa
     1981 ggatggtaaa ataactaaat atgaaaataa tccaatagta agtgaaatac caaaaggata
     2041 tacaggacat gtaagagacc caaaagtatt taaaagaaag gataaatact ttatgttact
     2101 tggagcacaa acaagtgata aaaaaggagt tataatagta tatgaatcta aaaactctat
     2161 agattggaat tttaaaggag aattaaatgt aaaaaacata gatgaagatt ttggttacat
     2221 gtgggaatgt ccagattata ttaatataga tgaaaaagat atattaatat tttcaccaca
     2281 aggagtagaa cctaaaggat ttgattatca aaatatatat aatgtagtat atgctattgg
     2341 taatatggat ttagataatt taacatttga aatagataca atgaaagaac tggaaaaagg
     2401 atttgatttc tatgctccac aaacatttat aaaggactca caaataatac tatttgcatg
     2461 ggctggaatg ggagaagttt tataccctac agataaaaac aaatgggcac attgtctaac
     2521 tgttccaaga aaattaaata taaaaaataa taagctattg caaatgcctg tagatgaatt
     2581 aattaaatta agatatgatg aaacaagtgg gcaaaatact ataaagaata atatcaatat
     2641 tatagaaaat aatgaaaatt tatatgagct taatattaat ataaaaaata ttgacagcaa
     2701 taaatttggg ctggaattat tttcatcaca agatgaaggt gtaaaattag aatttaacaa
     2761 attaggaaac attgtaactt tagacagaag caactttaaa aaagttttcg gtgttgaata
     2821 tggaacaaat agaaaagaat atataaatat tgatgaaaat actaatatca aagtactagc
     2881 ggatagaagt attttagaaa tttttataaa tgatggagaa gtagtattta ctagtagaat
     2941 atttgctaaa gaaaattcta atcaaataag ggtttatagt gataaaatag tagagtatga
     3001 gtatactaaa tttaaattaa agcaaggtat tgaattataa aaacacatta taaggggtag
     3061 aaaagatgaa aaaagtaatt agcataggag aagctttaat agactttata ccgaatcaaa
     3121 atggtggtaa attaaaaaat gtatcagaat ttagaagagt agcaggagga gctccagcaa
     3181 atgttagtgc tgttgtagca aagcttggag gaaaatcgag ttttatatct aagttaggaa
     3241 aagatgcatt tggtgattat ataatagatg tattaaatga agtaaatgta aatactgatt
     3301 atgtattgag aacaagtaaa gcaaatacag gacttgcttt tgtatcatta aaagaagatg
     3361 gtaatcgtga tttctcattt tatagaaatc caagtgcaga tatgctttta gaagctgatg
     3421 aagttaaaaa agagtggttt aataattgtc atatcctaca tttttgttca gtagatttaa
     3481 tagatagtcc aatgaaatta gcacataaaa aagcaataga atacgcactt gaaagtaata
     3541 gtataataag ctttgaccct aatataagat tacctttatg ggatagtgag caatcttgta
     3601 aaaaggcaat atcagaattt ttaccttttg ctcatattgt taagatatct gatgaagaat
     3661 tagaatttat aacaggagaa aatgatatag aaaaatcatt acataaactc tttgtgggga
     3721 atgttgaact agtattatat acaaaaggaa aagatggagt agatgcatac actaaaaaag
     3781 taaaaggtat gtgtaaaggg gttaaagtaa atgcaataga tacaaccgga gcaggagatt
     3841 cttatatagg ttcattttta tacaccttat tgtataaaca aataacattg aatgatataa
     3901 aagaaatgaa acaagaaacg ttaaatgagt atttagaatt ttctaattat tatgcagctc
     3961 gtagtacaac tattaaaggt gcgataagtt catatgcaac aaaggaagaa ataactgaat
     4021 ttataaaaaa tttatagtag gaatgagtaa taggttttga aggaagtaac atgtaaagag
     4081 tttttaagga tgtttactat gaaaataatt aacatataaa aagcaataaa gaggctgtct
     4141 caaaatagag ataagcctct ttatcattgt tgaaatgata aaaaatattt taattattgt
     4201 tactttttag aagaatatat atcttatttt aaataagcaa attatgtaag atttatttat
     4261 attatcaata ctttacttgg agtattatgt ctttagcagt tatctacttc aattgaatta
     4321 tctaaaatat aataaatttg ttttgcaaat tgacgagaat cttcttcttt ttctttattc
     4381 ataaaattag gtttacctaa atcacgttca acaagcattc ctatatattt taactgtgaa
     4441 tgcttacagt agcgcttcat accattttcc caaatatcag cacccttttc aggtctatat
     4501 ccacatgttg taataagtgc tactggtttt cctgcccata gagcggggcc tttctcatta
     4561 ccatagtatt tattcattcc atacaccaat ctgtcaagta gtgctttcat tggagaagtg
     4621 cagtaccaag aataaattgg agtagcaaaa acaattaaat cacacataag aattttcttg
     4681 aaaattttct gaacatcatc tttacaataa catccaaaat caaataagtt atcctgacac
     4741 tttttacaag caatacatgg ctctatttta caatcatata accatattac ttcaatattt
     4801 gaattataat tttctaattc ctcaataaaa ggttttaaaa tagcagcagt attacctttt
     4861 ttcttaggac ttcccataag aatgcatact tccatattga tacctccaca gtattttaaa
     4921 atagttttta gtgcttaata tagttttagg atactatgag aatacgttaa caacaataca
     4981 ctttgtatat ttgtaataaa attgaaacaa attgttttat caataaaagt tggaatgtat
     5041 ctataattaa aaatatttta ggtatgtttt tacatatatg tgtgtagtta actatggtaa
     5101 tttattgtaa aattatctta taggattata attgcttaat ttatgattat atttaaaatc
     5161 ttggaggtaa aaaatatgta ctcaaatgaa gactataaat ttatagaaga aaatgcacca
     5221 tgttatatat atgatgagac taatataatt gaaaaatgta aggaattgaa aaataatatt
     5281 ttaggttttg attttttata ttctataaaa acaaatccat ataacaaaat tgtaaaaagc
     5341 attgcagagc aaggttttgg agcagatgct tcttcaacta atgaagttat gatttcatca
     5401 aaatgtggag tttctaaaga tgatatttat tattcatcac caggcaaaac agagattgat
     5461 atagaaactg ttttagataa atgcataatt attgcagata gtattacaga aatagaactt
     5521 ataaataaga tatctaaaaa gcataatcag aaagttaaaa taggaataag aataaatcct
     5581 gattttacta tggatgatga tagtgctaaa tcaagcaaat ttggtataga tatagaagat
     5641 atgagcagtg tttttaagat gttaagtatg tgtgattatg tatctgtagt tggtattcat
     5701 atacatatta aatctcaggt attggatttt gaaaagttag gacattatta tgaaaaatgt
     5761 ttttttatag ctttaaattt aaataaaagt aagtatatta atattgaatt tataaatttt
     5821 ggtagtggac ttggagtagc ttatgataat cttagagaaa atccacttaa tcttaaagag
     5881 ctttcaaaat taactcaaaa gattgctttt actaattcaa acacactaaa atcaagactt
     5941 cttattgaat caggacgttt catagtttgt aaatcaggta attattatgt taaaattgta
     6001 gatattaaag tatcaagagg gaaaaaatat cttattgtaa aaaatggact taatggattt
     6061 atgagaccta ttatttctaa tttaattgaa aatattactt gtggagtaga attagaaggt
     6121 caagagccat tatatacatc aaatcatgcc ttttctcttt cagtattaaa taatttaaaa
     6181 gaagaagagt atgtaaatgt tgttgggaat ctctgtacat cattagatgt aattgcaaat
     6241 aatattaaat tgaaaaaagc aaacatagga gatttgattt caattagtaa tgctggaagt
     6301 tactcctatt ctttatcacc actattattt tcgagttatg aatttcctaa acaatattat
     6361 aaaagaaaag atggatatat tgagtaaaca atagcataaa ttaataaact tagtattatt
     6421 gaaaaaattt aaaatgcagg gggtgtaatt ctatatggaa ttgtggaaaa gaaatttatt
     6481 tgtatgttgg ataggtatgt tttttagttc tatagggatg agccaaatag cacctatact
     6541 tccattatat attaaacagt tgggggtaac tgatgttagt ttaatacaac agtattcagg
     6601 tataattttt ggatgtacct ttgtagtagc agcaatcttt tcgccaattt gagggaaagc
     6661 tgctgataaa tatggaagaa aatcaatgct tttacgtgca agtattggga tgggaatagt
     6721 tatatttacc atggcgtttg ttcaaaatgt ctatcagtta ttaggattaa gaatacttca
     6781 aggagttttt acgggttatg ctactgcatg tactactctt attgcaacac agacagataa
     6841 aaatcattca ggatgggctt tgggtactct tgcaactgca tcaactactg gctcattaat
     6901 tggtccaaca gtaggaggat atatagaatc aatcttaggt cttaaaagta catttattat
     6961 aacaggagga ttgttgtttg tatcatttat catctctatt ttatttgtag tagataattt
     7021 taaacctaaa gaaataaaag aatcaatttc tatacctaaa gaacaattaa atatattgcc
     7081 aaataaattt ttaattgcat ctatttttgt aaccacattc attactcaac tagctttata
     7141 ctctatagaa ccaattgtaa ccatatatat atcacaactt acaaattttg catcaaatgt
     7201 agctttaata gctggattga cattttctgc atcaggatta gcaaatttat tagcagctca
     7261 aaaacttgga aaaatgtcag ataaaatagg ccctcaaaaa gtattgttaa tttcactttt
     7321 atgggctggg attatattta taccacaagc ttttgtaaaa actgcatggc aactgatgtt
     7381 gttgagattt ttattagggt tgtcagttgc agggcttaat ccttctgtta acagcttgct
     7441 taaaaaaatt gcaccagaag aatatgtggg aaaaatattt ggatataatg catctgccca
     7501 gtatataggc tgttcatcag gagcattttt agggggacaa atatcagcac atttaggtat
     7561 tagaacagta tttttttcaa caagtttatt gttgtttatg aatgcacttt ggatgtataa
     7621 atttactgga ttgtttatta aagataagac taaataatca tactatttac atttctaatt
     7681 ttatgatgta aaataaatat tttttatgta atttatcata aaattatata aaaaataacc
     7741 ctatggtaaa aattggaaaa tattattatc gacaaaatct ttgacttaaa aactatattg
     7801 cgatagtatt aatttaataa aagtttgaga ggggcgtaag gttatgacaa tttcaaaaat
     7861 accacaagca gaattaaaag ttatgaagtt tatttgggaa aaaaatgata cagtaacatc
     7921 aaaagaaact attgaagcta tggaacgaaa atatggttgg aaacaaacaa ctacattgac
     7981 acttttatca agacttgtta aaaaacattt tttaagtgca gaaaaaatag atagatacac
     8041 tcattataca atagttgttg gacataagga gtatttaagt gttgagacaa aagatttttt
     8101 aagcaatata cacgacaatt ctttacagag tttaatttca gcactacatg atgatgaagt
     8161 tgttgataaa gatatgttgg atttatttga aagtcatttt aaaaatttag aagaagagta
     8221 attatatcag gatagaactc taagaattta attaatctat ggctgaaaac cataaatggt
     8281 attatttaat cagctactca ctattcataa agtaatatta aataggttct ctaattagta
     8341 aaatgcctaa aataattgga atagggagta tcaagttaaa tgataccact tatttaaata
     8401 agaaatgatt tttaaaattt aaaataattt tataacttgt caatattcat taatctaaag
     8461 tattatttct atttaaccat atcaaaatat attttactat ttttaattat tacaatataa
     8521 acctgtcttt tgttattata ggtaaactaa aagtaagaaa tgatttttat atttt
//
LOCUS       DAMJXI010000113         8355 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.120, whole genome shotgun sequence.
ACCESSION   DAMJXI010000113 DAMJXI010000000
VERSION     DAMJXI010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8355
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.120"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(81..1757)
                     /gene="bclA2"
                     /locus_tag="PC465_003521"
     CDS             complement(81..1757)
                     /gene="bclA2"
                     /locus_tag="PC465_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA2"
                     /protein_id="HDF2650790.1"
                     /translation="MSDISGPSLYQDVGPTGPTGATGPTGPTGPRGATGATGANGITG
                     PTGNTGATGANGITGPTGNMGATGPNGTTGSTGPTGNTGATGANGITGPTGNTGATGA
                     NGITGPTGNKGATGANGITGSTGPTGNTGATGANGITGPTGNTGATGATGPTGLTGAT
                     GATGANGITGPTGNTGATGANGVTGATGPTGNTGATGPTGSIGATGATGTTGATGPIG
                     ATGPTGADGEVGPTGAVGATGPDGLVGPTGPTGPTGATGANGLVGPTGPTGATGANGL
                     VGPTGATGATGVAGAIGPTGAVGATGPTGADGAVGPTGATGATGVNGATGPTGAVGAT
                     GANGVAGPIGPTGPTGANGVAGATGATGATGANGATGPTGAVGATGANGVAGAIGPTG
                     PTGANGATGATGATGATGANGATGPTGATGATGVLAANNAQFTVSSSSLVNNTLVTFN
                     SSFINGTNITFPTSSTINLAVGGIYNVSFGIRATLSLAGFMSITTNFNGVAQNNFIAK
                     AVNTLTSSDVSVSLSFLVDARAAAVTLSFTFGSGTTGTSAAGYVSVYRIQ"
     gene            complement(2115..2654)
                     /gene="hpt"
                     /locus_tag="PC465_003522"
     CDS             complement(2115..2654)
                     /gene="hpt"
                     /locus_tag="PC465_003522"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDF2650791.1"
                     /translation="MDIETKKWEVLYSEEKIKDKLRELGAIIEKDYKDKNLMVVSLLK
                     GSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGKVKVVSDVTTDIAGYDVLVVDDI
                     TDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFD
                     FGDYYRNVPYIFNVTDEDR"
     gene            complement(2982..4289)
                     /locus_tag="PC465_003523"
     CDS             complement(2982..4289)
                     /locus_tag="PC465_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HDF2650792.1"
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIV
                     ENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIA
                     EDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNE
                     PKVSASNDVAEKAESLMDTVTIQELIKNVEGIDFKDIEFLLDGVKMNEEMAEYGLKQK
                     TGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTA
                     ILPIVAYNKKFPQSDERLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGIS
                     WLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVP
                     PLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     gene            complement(4714..6489)
                     /locus_tag="PC465_003524"
     CDS             complement(4714..6489)
                     /locus_tag="PC465_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2650793.1"
                     /translation="MMIMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKELFRIAGTGV
                     YIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDICRECYKSGACVEFAEVCCPIICD
                     GDSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKL
                     ETLLNNMDKAVVSIDVDGKVDKYNSKFKELFNIKDSITGKNIFVELDFIKKPSINNFK
                     KDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIK
                     LENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIA
                     VNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSK
                     LLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLEKMVQNGTFREDLYYRLNVIPIKLP
                     SLRERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYS
                     VNMSSSSIITMNVIPQKIKNTSVEELEVKSDRIIPLDELEKIEIIKALNKYKDYKKDK
                     ELTAKALGISRATLYRKIEKYNIIS"
     gene            complement(6486..6623)
                     /locus_tag="PC465_003525"
     CDS             complement(6486..6623)
                     /locus_tag="PC465_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650794.1"
                     /translation="MEINYELIIIVMLFVILMSIQFTLNKIYLILKEIRQILMLKKNK
                     E"
     gene            complement(6701..7270)
                     /locus_tag="PC465_003526"
     CDS             complement(6701..7270)
                     /locus_tag="PC465_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF2650795.1"
                     /translation="MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIG
                     NLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVD
                     QFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHE
                     VFNIFSRLNFDGMIKESNKLKYIYVGKRR"
     gene            complement(7454..8089)
                     /locus_tag="PC465_003527"
     CDS             complement(7454..8089)
                     /locus_tag="PC465_003527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2650796.1"
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSD
                     SFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDE
                     ENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFA
                     KNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
BASE COUNT         2392 a         1665 c          958 g         3340 t
ORIGIN      
        1 taaacctatt aaatattatt ctatttattg gtatgtggaa ttatattgtt tattatttta
       61 tagtcttttc atcatataaa ctattgtatt ctataaactg atacatatcc agctgcagaa
      121 gtacctgtcg tgcctgaacc aaatgtaaaa cttaaagtaa cagctgctgc tctagcatca
      181 actaaaaagc ttaaacttac acttacatct gatgaagtaa gtgtatttac tgcttttgca
      241 ataaagttat tttgagctac tccattaaag ttagtagtaa ttgacataaa tcctgcaagt
      301 gaaagtgtgg cacgtatacc gaaagataca ttgtatatcc ctccaactgc aagatttata
      361 gtactacttg ttggaaaagt tatattagtt ccatttataa atgatgaatt aaatgtcact
      421 aatgtattat tcactaaact tgaagaggac actgtaaatt gtgcattgtt tgctgctaac
      481 actcctgttg ctcctgtcgc ccctgttgga cctgttgctc catttgctcc ggttgctccg
      541 gtcgcccctg ttgctcctgt cgctccattt gctccggttg ggcctgttgg tcctatcgct
      601 cctgctactc catttgctcc cgttgctcct actgctccgg ttgggcctgt tgctccattt
      661 gcacctgttg ctcctgtcgc tcctgttgct cctgctactc catttgctcc ggttggaccg
      721 gttggaccta ttggacctgc tactccattc gctccggttg ctcctactgc tcccgttggg
      781 cctgttgctc catttacacc tgttgctcct gtcgctcctg ttggacctac tgctccatct
      841 gctcccgttg ggcctgttgc tcctactgct ccggttggac ctattgcccc agctactcct
      901 gttgctcctg tcgctcctgt tggacctacc aaaccatttg ctccggttgc tcccgttggg
      961 cctgttgggc ctaccaaacc atttgctccg gttgctcccg ttgggcctgt tgggcctgtt
     1021 ggacctacca agccatctgg acctgttgct cctactgctc ctgttggacc tacctctcca
     1081 tctgctcctg ttggacctgt tgctcctatt gggcctgttg ccccagttgt tcctgttgct
     1141 ccagtcgctc ctatacttcc tgttggacct gttgctcctg tatttcctgt tgggcctgta
     1201 gcacctgtta ctccatttgc tccggttgct cctgtatttc ctgttggacc tgttattcca
     1261 tttgctccgg ttgctccggt tgctccagtt agtccggttg gacctgttgc tcctgttgct
     1321 cctgtattcc ctgttggtcc tgttattcca tttgctccag tcgctcctgt atttcctgtt
     1381 ggtcctgtag agcctgttat tccatttgct ccggttgctc ctttgtttcc tgttggtcct
     1441 gttattccat ttgctccggt tgctcctgta ttccctgtcg gacctgttat tccattcgct
     1501 ccagtcgctc ctgtatttcc tgttggtcct gtagaacctg ttgttccatt tggtccagtc
     1561 gctcccatat ttcctgttgg acccgttatt ccattcgctc cagttgctcc cgtatttcct
     1621 gttggtcctg ttattccatt tgctccggtc gctccggttg cacctctagg ccccgtcggt
     1681 cctgttggac cagtagcacc tgttggccct gttggaccta catcttgata taaacttgga
     1741 cctgaaatat cactcatata attaatcctc cttttttaaa gttagagtaa tactctataa
     1801 atattgagta ttaccctata taattatatg aatcgacaat ttcttatgtg ataatgtatc
     1861 tatttgctta tatcaacata tatgctttga ttcttgaatt tcattacttt tttgtaaaat
     1921 cttttacaat tattaataca attaaaaaac tcatttccca tcaattattt aaaatttttt
     1981 tattatgtta taaaaaatag ataattaaat tgcataaaat taatttaata ctactttaat
     2041 tactttttaa ataaaaaaac ctcaacacga ttaataaaaa tcatattaag gcatccacaa
     2101 aattatataa ttgcttatct atcttcatca gtaacattga atatataagg aacatttcta
     2161 taataatcac caaaatcaaa cccatatcca accacaaact tatcttctat ttcaaatcca
     2221 caataatctg gcactaaatc gacttttctt ctgcttggtt tatccaaaag aacacagcat
     2281 tttaaactag caggattttt agcttttaaa tgttttaaca caaaatccat agtaagtgca
     2341 gaatcagtaa tatcgtctac aaccaaaaca tcatatcctg ctatatcagt agtcacatct
     2401 gaaactactt taacctttcc agtactttct tcattgtttc cataactaga tgtagtcata
     2461 aaattaactc taagtggtaa gtttatattt ctaactaagt ctgcacaaaa tataaagcta
     2521 ccttttaata gagaaactac cataagattt ttatctttat aatctttttc tataattgct
     2581 cctaattccc ttaatttatc tttaattttt tcttctgaat acaatacttc ccattttttt
     2641 gtttctatat ccataaaaag acctccaatt gtaataatcc ttcttaattt tataagagat
     2701 tgctcacttt ttcaatactc ttattcaata ttagtcaata ttattgagtt tttatgttca
     2761 ttcaacaatt attaacaatg tatcttatat tttaagtagt tcatatatcc acactaaatt
     2821 acatactata tattttagac aaaaaaagaa aaaacttgca ctaacaagtt ttttctatta
     2881 tacataaatt tatacataat catattttat tagagggtac taattaaatt tatttatgct
     2941 atttttgtta tccctcataa tacaaaacat attataaagt actagtcaac tttattcata
     3001 tcattcatta catttaagat tatctcatct gttatagaca tacctttgtc acttactcta
     3061 cctaagtttt gtatactttg ctcaacactt gaaccaacta taccatttag tggtggtaca
     3121 aaacaatctt gcttagctat tatagcactt tgtatagctg cagatgctgc agaagataat
     3181 tttaatgcac aaccagcttt cgcaccgtca catatcattc cacttaagtc agctatcata
     3241 ttttctatag ctccttctat ttgcttttca gtaccattca taagccaaga gataccagca
     3301 gttgctccag tagaagcagc aacaccacat ccacatacag cagataatct tcctgtatag
     3361 ttcttaatat aaccagttac tagatgagat atagctaaag cttttgctag tctttcatca
     3421 gattgtggga attttttatt ataagcaacg attggaagaa ttgctgttaa tccatgattt
     3481 ccacttccat ttgaactcat aacaggcatt tttacccctg ccattcttgc atccgaagct
     3541 ccagcagtta acatcattgc ataatttata acatcattac ctaaaagacc ttcttctata
     3601 gactttttaa ttccatatcc gacaccaata ccagtttttt gttttaatcc atattcagcc
     3661 atctcttcat tcatttttac tccatctagt aaaaattcta tatctttaaa atcaattcct
     3721 tctacatttt ttattaattc ttgtatagtt actgtatcca ttaaactttc agctttttct
     3781 gccacatcat ttgaagctga tacttttggt tcattgtcta ataatacttc tccatctttt
     3841 tctaagaacg taaaattatc atgtttagtt cttattctca ctttagcaat atgatttttt
     3901 ccttttaaca caacttctat aaatactttc tctcttgtat cagcaggtgt tattgatagt
     3961 ggagtattat ccatataatc ctcagctatt ttaacttcct cttttgttag agtttctaac
     4021 acacttaatc cattttcaga atgtccacct actataccta gagctgctgc aatttttaat
     4081 cctaatcttt cagtacctgg tatacctacg cacataccat ttttatagat actaggacta
     4141 actaacatac gattttcaac tatttcttct cctaataatt cctttgcctt tgcacatgct
     4201 agagctaagg ctactggttc agtacaccct actgctggtt taacttctgc ctttaacatt
     4261 tccactaatt cttttcttat atctctcatt atatataaac ctcccaatta agtttagatt
     4321 tagtactcaa ataattaatt aaataatttc ttatctatat ttatagcaaa atacatgcca
     4381 tattttttat atctttttat atttttagtc ttatattcta taaccattgg tatgactgct
     4441 tctatttatg tatttttttt atttacatag agtatttata ttctttaaaa tggataaaca
     4501 tatgacaatt tcgcaaaaag acaaaaaaaa gtctcaaaat gagattctat atcattttga
     4561 gacggctcaa atgtattatt ttttaactta taaaaaccat tttttaattc ataaaaaaag
     4621 attctgcaaa acacttatag tataagttta aagctttctt taaagttatg aatttagaaa
     4681 aatttaaatt ttatatagct ttttattata ttactatgaa attatattgt atttttcaat
     4741 ttttctatat aatgtagctc ttgatattcc aagtgcttta gctgttaatt ctttatcttt
     4801 tttataatct ttgtacttat ttaaagcttt tattatctca atcttctcta gttcatcaag
     4861 tggaattatc ctatcgcttt taacttctaa ctcttctaca gaggtattct taattttttg
     4921 aggaattaca ttcattgtga ttattgaaga agaagacata ttcacactat attcaataat
     4981 attctgcaac tctcttatat tccctggcca cttatattcc atcatagcat caacaaccct
     5041 gctatctatg tcaataacat ttttatctaa tttttttgaa tactctttaa ccatatgctt
     5101 gattataagt gggatatctt cttttctctc tcttaaactt ggtaatttta taggtataac
     5161 atttaatcta tagtataaat cttctctaaa agtgccattt tgaaccattt tttctaaatc
     5221 tttatttgta gcagcaataa ttcttacatc tattgaaaca tttgatttac ttccaatttt
     5281 attaagttcc ttttcttgta atactctcaa taactttgac tgtaaatgca aactcatatc
     5341 tcctatttca tctaaaaata tacttccctt atgagctact tcaaacattc caagctttcc
     5401 acctttttta gctccagtaa aagctccctc ttcatatcca aataattcac tctctaataa
     5461 attatccggt atagcagcac agtttacagc tataaaagga ttatctactc tattgctatg
     5521 gttgtgtatg gctcttgcaa atagctcctt acccgttcca ctttccccag taataagtac
     5581 tgttgatgtt gatttagaag ctattagggc ttccttttta gaatttctta tagctacact
     5641 ttctccaatt atgttttcca attttattct ataatcttta ttcatcttat tgtagttttt
     5701 tatagcatct cttttatcta taaaatcaat aacatatccc tttaactcat tttttaatac
     5761 tattttattg atattgtata ttcccttcga atcatatcca tatcttttat aaaaaaaact
     5821 acaggatttg tccttcttaa agttatttat agaaggtttc tttataaaat ctaattcgac
     5881 aaatatgttt ttgccagtta tactatcttt tatattgaaa agctctttaa attttgaatt
     5941 atatttatca acttttccat ccacatcaat agacacaaca gctttgtcca tattgtttaa
     6001 tagtgtctct aattttttct tttctaattc aagctcataa gttttaattt gtgcttttaa
     6061 tttattagat attaggtctg ccattttgcc taaaaagttt ataagaccac ttttattatt
     6121 ttctataatt tgtgcttgtt cttttgtaaa ggctataagg cctataacac catgagaatc
     6181 gccatcacat ataataggac aacacacctc tgcaaactct acacaagccc cacttttata
     6241 gcattcccta catatatcac tactctttgg gtcatcaatt agtattgtaa tctgttctgt
     6301 aagtgatttt ttaaaagccg tatatttatc tactttctca cctattttgt ctatatatac
     6361 tcctgtacct gcaatcctaa ataactcctt atttactata gttacatcta tattgagtac
     6421 tgatactata gcttcagcta tattttgaat atcagatttt atatattcta aacctatcat
     6481 aatcatcatt ccttattttt ctttaacata agtatttgtc ttatttcttt aagaatcaag
     6541 tatatcttat ttaaagtaaa ttggattgac atcaggatta caaagagcat aacaattatt
     6601 attaactcat aatttatttc catctaaaca tctccttata acaaaagact aggcttaacc
     6661 tagtctttta tattatatcc atatttatat tttaactcat ttatcttctt tttcccacat
     6721 aaatatattt taatttattt gactctttaa tcataccatc aaagtttaat cttgaaaata
     6781 tattaaatac ttcatgtgga tagtgaatct ttgcaacaga accacaaaat ttatgtttaa
     6841 gatagtttaa cttaactttt aaattcttta aatttaaatc ctctaatata acctctccat
     6901 tgccctttaa cactctttgt atttcagatg aagctttttc acaatctgta ataacattaa
     6961 attggtcaac tattattatc ttgttgaact gattatcatc aaatggtaga aactctaact
     7021 tacctttaac tacattgcaa ttttcattat acactagaga ataacagaca tcttcataat
     7081 tactattctc cagtatagtt acagaagttc caagacctct caatctcttg cctaggtttc
     7141 ctatatgacc aacaagcaat attttatcac ctacattata ctcaattgta tccaaaaaac
     7201 attctaattc atcagatgta tatttagctt taaccggctg tttatttatc tgacataata
     7261 tgcttttcac aatgcttcac ctcttcattt cctcaattat aaattatgta cagattacat
     7321 tataataaat ggcgagcaac tattcaagag atatttcatt agtatttttt taaacaatct
     7381 ttatacattt taatatgata ttataccaaa tttattagga ttttattcat aaaaatcagt
     7441 ctatttttca tgtttattca ttgttatttt catccaattt ttttattttc gatatggata
     7501 cttcatatgc catttttttg accacattat tttcatctat ttttttctca tattctctac
     7561 tttgaaccct accccaaagc tgtattctat caccaacctt tagattcttt gcaaatttag
     7621 catttctacc ccaaactatt gatggtatat aatcagattt attataaggt ctgtttatag
     7681 caactaataa atcggttatt tcccttccta aaggtgtctt cctatacaca ggttccttac
     7741 atacatatcc atctaaaaat atactattag ggtctttatt ttcctcgtct atgcttttta
     7801 tttctctgac aaacactgta agcactaatc tatttttatt atttaatgtt ttgttatatg
     7861 atcttaattg gcctacgaca ttgactaaat tttgtttatc aaggtcaata tcttggagaa
     7921 gtctttctga tacagtcatt ggaagtatat caaaagaatc gcttagtctg tttattttta
     7981 ttttcatatt ataaaatttt tctccaaata tctcatggct aaattctagc ttattgtcta
     8041 actcccctct taagtttact acgttattct catctttaac agctatcata ttttatccct
     8101 ccacaattgt taattcttat atttctggta tcagcttata taataaatat atttataagg
     8161 gatgtatttt attacaaatc tttgattgct gtttaaaagt ttttatttag ttataaattt
     8221 catttaatat ttcactttta taattataaa attattatct ttttgtacca catatactaa
     8281 ttaaactacc tatttcagtt ttatattaat tataaaaatc ctattatata gttaataagt
     8341 catatataac ttaaa
//
LOCUS       DAMJXI010000114         8140 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.121, whole genome shotgun sequence.
ACCESSION   DAMJXI010000114 DAMJXI010000000
VERSION     DAMJXI010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8140
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.121"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            164..1477
                     /locus_tag="PC465_003528"
     CDS             164..1477
                     /locus_tag="PC465_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008790773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2650797.1"
                     /translation="MKKDMLRNSLLYIKRKKKKSIIVLFILTAILISLYTCLSINKFS
                     NNVESIIYRAANSSFILKSKNSQELIDTKEVEGIKNLDRINEYNLEYETLAQLKGDDV
                     FGGEQKVEISNLNSEYENLLKIFGVRDSSLSNDFTSEVFKIVEGRHIGKDDKNKIIVH
                     EELAKQNQYELGDKVSIKQIKQYDPDDEDINSNIGLENEYEIVGIFSGKKQESYTGFS
                     SDYSENMAFIDYSSSQKISGIDSNYEKLNQATYFVNSPENMGKVISSIKNMNINWSNI
                     DLEKNTKIFDDISTTVGSIKGIIQIITYSIIVGGCIVLSLILILWLRERIYEIGILLS
                     IGIGKREIIGQFILELVFISIPSLFISTLIGNLVTRKILSEIILKEKIISTLSNASNK
                     IFGSENIFIICQSYGLLILIILLSVLITSGIILMKKPKEILSKMS"
     gene            1490..2140
                     /locus_tag="PC465_003529"
     CDS             1490..2140
                     /locus_tag="PC465_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008790772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2650798.1"
                     /translation="MSILNMKNVSYNYKNSKEKILRDVNANFELGKFYAIVGKSGVGK
                     STFLSLLAGLDVPVKGEIQFEGVDISKKGYSHHRRKQVSLVFQNYNLIDYLTPMENVR
                     LVNKKANKEILLELGLDESQINRNVMKLSGGQQQRVAIARALVSEAPIILADEPTGNL
                     DESTALEIIEMLNKLAKSRNKCVIVVTHSKEVAKAADYILEIKNKNLKEVNFKKNS"
     gene            2164..3540
                     /locus_tag="PC465_003530"
     CDS             2164..3540
                     /locus_tag="PC465_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2650799.1"
                     /translation="MLKNALSYITRKKLKSIIIFAIILIMATLSLVSISIKNATNNAS
                     KETFKNITNSFSMQINRRVNPGTARGAGNVKGKDIKKIADSKEIEGYIKRINGVGDLV
                     DHDIIETEETKRNQSAERKKSFKNAVMVTGVNDSSKEDKFVSGAFKLVEGNHLKTGDK
                     GKILIHKDLATKNNLKVGDKMKIKSNLFDADNEKQANETIEVEIIGLFEGKNKSGVYY
                     SQEFYENNVVTDIDTAARLYGNTEDTAIYQDATFFVKGDIDLDAVIKKMKSLDIDWKS
                     YDLIKSSSNYPALQQSISGIYKVADKLFLGSLIFAGVVLSLLLLLWINARKKEIGIML
                     ALGITKAKIMGQFIMELMIIGSFAFAGSFFLASYTGKTIANKVLNSVTSDIAKKMASD
                     ASSANLGAGVEVDGFNKTLTSLNININSLDMVYVVIFGVGIMLIALLIASNKMLRKHP
                     KELLTDIE"
     gene            3587..4243
                     /locus_tag="PC465_003531"
     CDS             3587..4243
                     /locus_tag="PC465_003531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2650800.1"
                     /translation="MNILVVEDEDMILEGICEYLGEHEYYCIAASDGQEAIEKFKNNE
                     IHLVLLDIMLPKLNGIEVLQYIRKTSKIPVLMLTAFNDDDYKIKAFSGLCDGYIEKPF
                     SLSLLETRINALLKRHYSNYSIFNYKDCQVNFTSYKATYKGEDVSVNAKELKILELLL
                     KNENIVLTRNQIIDGVWKEDESIPYDRVVDVYIKELRKKLGLDCIKTIRNVGYKITIK
                     "
     gene            4240..5568
                     /locus_tag="PC465_003532"
     CDS             4240..5568
                     /locus_tag="PC465_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008790769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2650801.1"
                     /translation="MKKIKLFPKIFLYTFAIMSFLIIISHLLIYFIFPITYLENRKDS
                     IKNTADILAESIDGLDKSFINKYLELFSKNNEVKVFIKNGAIDNEVNLENKIDINLDS
                     ENNSVIIEERSVKTREDENLVLYFVSSKDMKREAKNISLSFLPYTLIVSFIFSIAISY
                     FYTKIIVSPIVEITKVTNNMMKLEKDALLKVKSYDEIGSLKNQINTLYIRLLGVIDDL
                     DKKNKEIIELEKMKVEFLRSTSHELKTPLASLRIILENMKYNVGKYKDRDKYLSVSIE
                     TIDKLTKMTVEILKVSSFQELKDDKELLNINQEVKTILEDYMVLSNNKNIEINNFLDE
                     EEIYMSKLALRKVLANLVSNAVKYSYANGKINIGVKNNYFFIENSCEPLNEKQIKESF
                     DLFSGVEDKSSNGLGLFIVKNILLNYGINYKFEKSDIGMIFYFKLPNIYS"
     gene            6183..7349
                     /locus_tag="PC465_003533"
     CDS             6183..7349
                     /locus_tag="PC465_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008790768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF2650802.1"
                     /translation="MNDMKFIETLKQKRKACDYSQSRLAQELQISRQNLNEIENGKTK
                     AGKEMKHILLHYLDYCNCTQPFTLTIDYLRVRFPTTDALEIIKNVLAMKSEYFIHEDY
                     GMYGYEEQYVYGDISVNVSKDSSMGVLLELRGMGCRNLEYVLQARGIDWYSFLSCCID
                     CQGVFKRIDLAVNDMGGLLDIEILRERYYANKVWKRSRTHEAVDSGKLSGTHGDTAKT
                     FYIGSKNSSIYFCLYEKEKEQKSKGIKTDIKNRFEIRLKNEKAGQTIEQLVFSRNPEQ
                     TIASLILTQIDFPDYILWDIFLDNVTTSLPFIMTPVAVNMDKTKRWLERQVMPSLLMI
                     KEIEKKTGANYLEEIDRHTKLTEKQELKIKQMTTDIANMIEKDTTVPQGNDGIF"
BASE COUNT         3278 a          898 c         1453 g         2511 t
ORIGIN      
        1 aataacctgt gttttcctgc ttgcaaatag aaatacagta aaaagatact tcacattaga
       61 atagaggtat cttttttttg ctttataaaa aataaaaaga aataaaaaat aagatttcat
      121 aaatatttca taaaagcaat ttatactata gatgatagga ggtatgaaaa aggatatgct
      181 aagaaattca ttattgtata ttaaaagaaa gaagaaaaaa tctataattg tattatttat
      241 actaacagca attttaataa gtctttatac atgtttatct ataaataagt ttagtaataa
      301 tgtggagagt attatttata gagcagccaa ttcttcattt attctaaaga gtaaaaacag
      361 ccaagagttg attgatacaa aggaagttga aggtataaag aacttagata gaattaatga
      421 gtataatctt gaatatgaaa cacttgcaca attaaaaggt gatgatgttt ttggtggcga
      481 gcaaaaagtt gaaatatcaa atttaaattc tgaatatgaa aatcttttaa agatttttgg
      541 agtaagagat tctagtttaa gtaatgattt tacaagtgaa gtatttaaaa tagtagaagg
      601 aagacatata ggaaaagatg ataaaaataa gataatagtt catgaggagt tagctaaaca
      661 aaatcaatat gaattaggtg ataaagtttc aataaaacaa attaaacaat acgatcctga
      721 tgatgaagat attaactcta atattggatt agaaaatgag tatgaaatag ttggtatttt
      781 ttctgggaag aaacaagaaa gttatactgg attttcttcc gattacagtg aaaatatggc
      841 ctttattgac tatagttcaa gtcaaaaaat atctggtata gattctaatt atgaaaaact
      901 aaatcaagca acgtattttg tgaatagtcc agaaaatatg ggcaaggtaa tttcgagtat
      961 aaaaaatatg aatattaatt ggtccaatat tgatcttgaa aagaatacaa agatctttga
     1021 tgatatatca actactgtag gatcaattaa aggaataata caaataatta catattcaat
     1081 tatagtagga ggttgtatag tgctttcttt aatattgata ctatggctaa gagagagaat
     1141 ttatgaaata ggaatattat tatcaatagg aataggaaag cgtgaaatta tagggcaatt
     1201 tatattggag ttagttttta tatctatccc aagtttattt atttcaactt taataggaaa
     1261 tttagtaaca agaaaaatat taagtgaaat tatattaaaa gaaaaaatta taagtacttt
     1321 aagtaatgca tctaataaga tatttggaag tgaaaatatt tttattattt gtcaaagcta
     1381 tgggttatta attttaataa tattattatc agttttaatc acttcaggaa taatattgat
     1441 gaaaaagcca aaagaaattt tatcaaaaat gagttaagga gtaaaaaaaa tgagtatatt
     1501 aaatatgaaa aatgttagtt ataattataa aaattcaaaa gagaaaatct taagagatgt
     1561 aaatgcaaat tttgaattag ggaaatttta tgccatagta ggaaaatctg gagtaggaaa
     1621 atccactttt ttatcactat tagcagggtt ggatgttccg gtaaaggggg aaatacaatt
     1681 tgaaggtgtc gatatatcta aaaagggata tagtcatcac agaagaaaac aggtttcttt
     1741 agtatttcag aactataatt taattgacta tttaacacct atggaaaatg ttaggttggt
     1801 aaataaaaaa gctaataaag aaatattact agaattagga ttagatgaaa gtcaaattaa
     1861 tagaaatgta atgaagttgt ctggaggaca gcaacaaaga gttgcgatag caagggcgct
     1921 tgtatctgaa gcacctataa ttttagcaga tgagccaaca ggaaatcttg atgaaagtac
     1981 agcacttgaa ataattgaaa tgcttaataa attagcaaaa tcaagaaata aatgtgtaat
     2041 agtagtaact catagtaaag aagtagcaaa ggcagcagat tatattttag aaataaaaaa
     2101 taaaaattta aaagaagtta attttaagaa aaatagttag tttaataaag gagataataa
     2161 taaatgttaa aaaatgcatt atcatatata acaagaaaaa aacttaagtc aataattatt
     2221 tttgcaatta tattaataat ggcaacactt agtttagtaa gtatatctat aaagaatgca
     2281 actaataacg catcaaaaga gacgtttaaa aatataacaa atagtttttc aatgcagata
     2341 aatagaaggg ttaaccctgg aacagcaaga ggtgcaggaa atgtaaaagg gaaagacatt
     2401 aaaaagatag ctgattcaaa agagatagaa ggttatatta aaagaataaa tggtgttgga
     2461 gatcttgtag atcatgatat aattgaaaca gaagaaacaa agagaaacca aagtgctgaa
     2521 agaaaaaaaa gttttaaaaa tgcagtaatg gttacaggag ttaatgattc atctaaagaa
     2581 gataaatttg tatcaggtgc ctttaagctt gtagaaggaa atcatttaaa aacgggtgat
     2641 aaaggaaaaa ttttaataca taaagattta gctacgaaaa ataatctaaa agttggagat
     2701 aagatgaaga taaaatcaaa tctttttgac gcagataatg aaaaacaagc taatgaaact
     2761 atagaagtag aaataattgg attatttgaa ggaaagaata aatcaggtgt ttattattca
     2821 caagaatttt acgaaaataa tgtagttaca gatattgata ctgctgctag gttatatggg
     2881 aatactgaag atacagctat ttatcaggac gcaactttct ttgtaaaagg agatatagat
     2941 ctagatgctg taataaaaaa gatgaagagt ttagatattg attggaaatc atacgattta
     3001 ataaagagct caagtaatta tccagcatta caacaatcta tttctggtat atataaagta
     3061 gcagataaat tatttttagg tagtttaatt tttgcaggag tagtcttaag tttactatta
     3121 ttattgtgga taaatgcaag aaaaaaggaa ataggaatta tgttagcatt gggaataaca
     3181 aaggctaaaa taatgggaca attcattatg gaattaatga taataggatc ctttgcattt
     3241 gctggatcat tcttcttggc tagctataca ggcaaaacaa ttgcaaataa agtactaaac
     3301 agtgttacat cagatattgc aaaaaaaatg gcatcagatg catcttcagc aaatcttgga
     3361 gccggagttg aagttgatgg atttaataaa actctaacaa gccttaatat aaatataaat
     3421 tctttagata tggtttatgt agttatattt ggtgtaggaa taatgttaat agcacttctt
     3481 atagcatcta ataaaatgct aagaaaacat ccaaaagaat tattaacaga tattgaatag
     3541 aaatacagat ttagctgttt tatattgtag aaaggaaagt taaaagatga atatactagt
     3601 agtagaggat gaggatatga ttctagaagg gatatgtgaa tatttaggtg aacatgaata
     3661 ttattgtatt gctgcatcag atggacaaga agcgatagaa aaatttaaaa acaatgaaat
     3721 tcacttggtt ttattagata ttatgttacc taaattaaat ggaatagaag ttttacaata
     3781 tatacggaaa actagtaaaa ttccagtttt gatgttaaca gcttttaatg atgatgatta
     3841 taaaattaaa gctttttcag gactttgtga tggatatatt gaaaaacctt tttcactttc
     3901 tttgcttgaa acaagaatta atgccttgtt gaaaagacat tattccaatt attcaatttt
     3961 caactacaaa gattgtcaag ttaattttac aagttataag gcaacatata agggagaaga
     4021 tgtatctgtt aatgcaaaag aacttaaaat actggagctt cttttaaaga atgaaaatat
     4081 agtgttaacg agaaatcaga ttatagatgg cgtttggaag gaagatgaat cgattccata
     4141 tgatagagta gtagatgttt atataaaaga acttagaaaa aaattaggat tggattgtat
     4201 aaaaactata agaaatgtag ggtataagat aacgataaaa tgaaaaagat aaaattattt
     4261 cctaagatat ttttatatac atttgctatt atgtcatttt taataataat tagtcacctt
     4321 ctaatttatt ttatatttcc aattacatat ttggagaata gaaaagatag tataaaaaat
     4381 actgcagata ttttagcgga aagtatagat ggattagata agtcttttat taataaatat
     4441 ttagaactgt tttctaaaaa taatgaagtt aaagttttta ttaaaaatgg agctatagac
     4501 aatgaagtaa atttagaaaa caaaatagat ataaatcttg atagtgaaaa taattcagtt
     4561 attatagaag agagaagtgt aaaaactaga gaagatgaaa atttagtttt atattttgta
     4621 tcttcaaagg atatgaaaag ggaggctaaa aatattagct tatcattttt accatatact
     4681 ttaattgtta gttttatttt ttctattgct atttcatatt tttatacaaa aataatagta
     4741 tctccaatag ttgaaataac aaaagtaaca aataatatga tgaaactaga aaaagatgca
     4801 ttactaaaag taaaatctta tgatgaaata ggaagtttaa aaaatcaaat taacacatta
     4861 tatattagat tgctaggggt tatagatgat ctagacaaaa agaataaaga aattatagaa
     4921 cttgaaaaaa tgaaagttga atttctaaga agtacatcac atgaacttaa aacacctctt
     4981 gcaagtttaa gaattatttt agagaatatg aaatataatg ttggtaagta taaagataga
     5041 gataaatatc ttagtgtatc tattgaaact attgataaat tgacaaaaat gacagttgaa
     5101 atattgaaag tatcttcttt ccaagagtta aaagacgata aagaactttt aaatatcaat
     5161 caagaggtta aaactatttt agaagattat atggttttat caaacaataa aaatattgaa
     5221 ataaataact ttttagatga agaagaaatt tatatgtcta aacttgcact aagaaaggtt
     5281 ttagcaaact tagttagtaa tgcagtaaag tattcgtatg caaatggtaa gataaatata
     5341 ggagtaaaaa ataattattt ttttatagaa aactcatgtg aacctttaaa tgaaaaacag
     5401 ataaaagaat catttgattt attttctgga gttgaagata agagtagtaa tggattaggc
     5461 ctttttattg taaaaaatat attacttaac tatggaatca attataaatt cgagaaaagt
     5521 gatataggca tgattttcta ttttaaatta cctaatatat attcataaaa atgaaatagg
     5581 ctttttaaag atttacttaa aattcaaaaa gttgtatata tttattactt tcgactggga
     5641 tatagaactt ccaaatatat attgaaaggt atcaagaaat ccggagtttt gacgataatg
     5701 tattgaataa caattacgat tcgtttgcag taacaaaaga aagaagttga aaatatgaag
     5761 acagaatttt tatcaagcta tattacatta ttcagtagtc taaattccag tttatacgga
     5821 agataaactt aaaatatcac aaatagacga agtgatccag acacggtggc ggtcgaagac
     5881 atagagccac gccagctatg ctggcgagtg tatggattac ttcggaggta ggcaagcttt
     5941 agcgagccga tataaaagcc cccgttatct aacagggggg tactcttaca aaagacaaga
     6001 gcaaaaacaa atacaaaact gctgatatgc aacgatttat aaggttataa gaacttattt
     6061 cacttcacac cctattcttt ctacccgaca ggtctaaaac agcatatcaa tagcaaataa
     6121 ttataagata caaggtgtat gctcctatga gtatatgcct tttttgattg gaggaataaa
     6181 gcatgaatga tatgaaattt attgaaacat taaagcaaaa gagaaaagcc tgtgattatt
     6241 cgcaatcacg actggcacag gaactacaaa tcagcaggca gaacttaaat gaaattgaaa
     6301 acggaaaaac aaaagccggt aaagaaatga agcatatact tttacattat cttgattatt
     6361 gtaattgtac tcagcctttc actttaacga ttgactacct gcgtgttcgt tttcccacca
     6421 cagacgcatt ggaaattata aaaaatgtac tggcaatgaa gagcgaatat tttattcatg
     6481 aagattacgg aatgtatggc tatgaagaac agtatgtcta tggggatatt agtgtaaatg
     6541 tttctaaaga tagttctatg ggtgttttat tggaattaag aggtatgggg tgtcggaact
     6601 tggaatatgt tttacaggca agagggatag actggtattc ctttttaagc tgttgtatag
     6661 attgtcaagg tgtttttaaa cgcatagatt tagcggtcaa tgatatgggc ggattgctgg
     6721 atatagaaat tctaagggaa cgctattatg ccaacaaggt atggaaacgt tcaagaaccc
     6781 atgaagcagt agacagcggg aaattatcgg gtacacatgg agatactgca aaaacttttt
     6841 atatcggttc aaagaatagt tctatttact tttgcctgta tgaaaaagaa aaggaacaaa
     6901 aaagcaaagg cataaaaaca gacattaaga accgctttga aattcggcta aaaaatgaaa
     6961 aagcaggaca aacgatagaa caacttgttt tttcaagaaa tcccgaacag accatagcaa
     7021 gccttatcct cacacagata gattttcccg attatatttt atgggatata tttttggata
     7081 atgtaactac ctcacttcct tttattatga cgcctgttgc tgtcaatatg gataaaacaa
     7141 aacgctggtt agaaagacag gtcatgccct ctttattgat gataaaagag attgaaaaga
     7201 aaacaggagc aaattatctg gaagaaatcg acagacatac aaaactaaca gaaaagcagg
     7261 aattaaaaat taaacaaatg acaacagaca tagcaaatat gattgagaaa gataccactg
     7321 ttcctcaagg gaatgacggt attttttaat ttctttaaaa aatctgcaac aaaacggcta
     7381 cttgcgtaca gatatggtgc gaggaaagga aatctgactt tttttgaaaa caggtcatca
     7441 aatcggtggt tgctgtccct atatgatgtg aaagaagaaa cgtttttcaa tttcaactta
     7501 acaatccgta gttgccgttc cctatatgga gcaaagaaaa tcttttattc cacagttggc
     7561 agttacggcg ttgcatgggt agttaggggg gggaaaagaa aatcagattt tttcatcatc
     7621 aacttagcag aatgacactt tctttcccta tatggtacag gaaaagaaaa aagtttggaa
     7681 gattggttac gcttctgttc ttttccaacg cggtatatag gaaagatgat tttcttcttt
     7741 cgtgttcttt gacaactgaa taaagcagtt caatacgttt gacagacagc gagccgttga
     7801 aacagatacg ccatgacctt ttccctgcta aagtgagcga accttatctg tgttcctgta
     7861 agaaacttgt cctttcctac cgccatgacc tgtcctgtct gataatgata ctcccgtaca
     7921 gccacagctt gagcgttcag agcgtcgcac gcaatgggta cggctacata agaactatgc
     7981 agaggtggaa ctcctgtggg ctatgacaaa agccgttgaa ttgcttagaa aagattttta
     8041 cagaaagggg gtatgtgtta ttgctgatat tgtaaaaaca aggcaggtaa agacgaataa
     8101 taagcgtggc attggcaaca gaggaaaaac aaaaattgtt
//
LOCUS       DAMJXI010000115         7808 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.122, whole genome shotgun sequence.
ACCESSION   DAMJXI010000115 DAMJXI010000000
VERSION     DAMJXI010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7808
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.122"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            295..816
                     /locus_tag="PC465_003534"
     CDS             295..816
                     /locus_tag="PC465_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2650803.1"
                     /translation="MDIAKLILNPARLRILQYIRLHGSVRTSDIVKYLNDIPRATVYH
                     HVKILEENNMIEVIKENRVRGTIEKVYALKEYTTSMEGETFVALSTAFYVGLMQEMNE
                     YFSRKEQDHKKDNVFFSSALLYMSDNEYENLLKSIADLLKPYIEQKPKSNLKLRKLSI
                     ISSPPVADNDKTK"
     gene            850..1626
                     /locus_tag="PC465_003535"
     CDS             850..1626
                     /locus_tag="PC465_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2650804.1"
                     /translation="MKFHEFGNKNRPHIMLIHGGGNAWWNYLRQAEVLSNKYHVILPT
                     LDGHGEEYETTYISTEDTADKLISYIDENCSGHLFALCGVSLGGQIVMELLSRKPNIT
                     KKAIIDGSICYPRPLMARFCIAGIRFFGGLLFSEKACRFQIAMMPKLLPENMQYPDEI
                     KAYYMTDMPHVRKETFYNMYRTYMMNYTLKENVKKTTAQVMYWYGEKEMKCVKKSAKL
                     FQSYVPSCEIYEAKSYNHGYLSLYLPNEWLEIAEPFFQKE"
     gene            1969..2922
                     /locus_tag="PC465_003536"
     CDS             1969..2922
                     /locus_tag="PC465_003536"
                     /EC_number="3.4.24.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPR endopeptidase"
                     /protein_id="HDF2650805.1"
                     /translation="MISVRTDLALEASEMCEKSQEGSSIPGVKIETKELENCIVTKVE
                     VIDRQGAEIMNKDIGKYITLESNLMKFDDDESREEMISYLKEELVDIFGQDKNKKTLV
                     IGLGNRNITSDALGPKSVSKTLVTRHLFKNYNKDYDDDFTEVSALSPGVMGVTGIETS
                     EIVKSLVEKVKPDRVVAIDALASRKMERVNSTIQISTAGISPGGGVGNTRKSLTKETL
                     GVDVIAIGVPTVVDAATLTIDVLDMAIDNLIAQSEETESFYEMLKKLKEEEKYHLIKD
                     SLDPYDKNLIVTPKDIDDTIENLSIIISEGLNRSLHPGRLV"
     gene            2940..3959
                     /locus_tag="PC465_003537"
     CDS             2940..3959
                     /locus_tag="PC465_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein P"
                     /protein_id="HDF2650806.1"
                     /translation="MFKKCIKVVTLTFILVCILPGKSLALNQDDFLKFLVNSSYPEAK
                     VEGNDTENKKNNKNKETSKENKEESKEENTKSKDASKVDNKKESEKEYIKLYVGKENV
                     PDIESKNSDTTETNTTSSSDYKDDLRVTKENPRILIYHTHGCETYSNSPDGNYHSRDK
                     KNSVMEVGSALTSALDSKGWGVVHTTKYHDYPSYNNSYASSLKTIQSILPKYNSVDIA
                     IDLHRDARDLTNPATKEKDHLKYTTMINGERVSKFFFVVGGKNTNRKQLRALAEDITA
                     FAEKKYPGLVSPIVEKDYARFNQFAVKNHMLVEIGNNATSVEESKATTKYLAEILDEY
                     FKQKN"
     gene            3990..4241
                     /locus_tag="PC465_003538"
     CDS             3990..4241
                     /locus_tag="PC465_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650807.1"
                     /translation="MSRLEKNIESKSKLRKYKYIMRILFLITMIICTSVCVFIVDSNA
                     KSMLGMKQYDFPSIKFDITKFDFDIPNFDIHEIIKKFNK"
     gene            4523..6328
                     /gene="lepA"
                     /locus_tag="PC465_003539"
     CDS             4523..6328
                     /gene="lepA"
                     /locus_tag="PC465_003539"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HDF2650808.1"
                     /translation="MDNKQSRTRNFSIIAHIDHGKSTLADRLIQQTGLVSERDMKSQL
                     LDNMDLERERGITIKLQNIRLMYKAKDGNEYYLNLIDTPGHVDFNYEVSRSLAACEGA
                     LLVVDAAQGVEAQTLANVYLAIDQDLEILPIINKIDLPSARPEEVKNEIEDLIGLDSS
                     EAPLISAKTGLNIEDVLEDIVKNVPPPKGDNEAPLKALIFDSYYDAYKGVVAYVRVFE
                     GTVKKGMTIKMMNTNKKFEVTEVGVMAPGQTELSELSAGDVGYIAASIKDIRSCRVGD
                     TITDSNNPTEEPLPGYKKATPMVYCGIYPGEGEKYENVRDALEKLQVNDAALEYEAET
                     SAALGFGFRCGFLGLLHMEIMQERLEREFNLDIITTAPSVIYRVTKMDGEVVMIQNPA
                     NLPEPSEIKMIEEPIVKGDIIVPKDYVGVVMELCQERRGNMLNMEYIDERRVMLHYDL
                     PLNEVVYDFFDALKSRTRGYGSLDYEVKGYVASTLVKLDILINKEQVDALSFIVHETR
                     AFPRGKAMCEKLKGEIPRHQFAIPIQAAVGNKVIARETISALRKDVLAKCYGGDISRK
                     KKLLEKQKEGKKRMRQIGSVEVPQKAFMSVLKLDE"
     gene            6477..>7808
                     /locus_tag="PC465_003540"
     CDS             6477..>7808
                     /locus_tag="PC465_003540"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HDF2650809.1"
                     /translation="MINIEIPKKVDYIIKELEKNGYEAYIVGGCVRDCLLERVPNDWD
                     ITTSARPEVVVELFEKTIPTGIQHGTVTVMIEHEPFEVTTYRIDGNYSDGRHPDSIEF
                     TNNIVKDLSRRDFTINSIAYNSKTGLVDPFNGYEDIQNKYIHCVGNPVDRFEEDALRM
                     LRAVRFSAQLNFKIAEGTKQSIHKKADLIKNVSIERIQTEFNKILVSDSSKLNLLKST
                     GLLKFIIPEICELEDVTQHNPYHIYDVQKHTLIATEAIEDELYLKLTMLFHDLGKKVT
                     KTTDKNGVDHFYTHSRESVKIAKKILKRLKYDNYTINKVLILIQYHDYRIEPKRKIIK
                     KLLNKLEDVGLFEDLIKVNWADTLAKNPKYAKQKILNLIECEKEFKHIINQKECFNLK
                     DLAINGKDLISIGIKPGKDIGYILNKMLEIVINNPELNEKEILKEKALNIYT"
BASE COUNT         3130 a          878 c         1390 g         2410 t
ORIGIN      
        1 agaaattact catttttgta aatttaatga aaaattataa aaatataaat ttatatgctt
       61 aattaagata atttttccaa taatcaagat aatttttttc attagtatgt atgatagatg
      121 catcaaacaa tataactaat atgttagaag gttatatgta attaatctca gtgtttatat
      181 agaatagcat ttgtagcatt tattatagtt gtaattacta cttatatcat agacttgaat
      241 agtctaaaaa aatagactat aatattttta tagactaaag aaagggctga taagatggac
      301 atagcaaaac taattttaaa tcctgcaagg cttcgtatct tacaatatat tcgacttcat
      361 ggcagtgttc gtacatctga tattgtaaag tatttaaatg atattcctcg tgcaacagtt
      421 tatcaccatg taaaaatttt agaagagaac aatatgattg aagtaattaa agaaaatcgt
      481 gtgcgtggta ctattgaaaa ggtttatgca ctaaaggaat atacaacatc tatggaagga
      541 gagaccttcg ttgcactttc tacagcattt tatgtaggtc tgatgcagga aatgaatgaa
      601 tactttagca gaaaagagca agaccataaa aaggataatg tatttttctc ttcagcatta
      661 ctatatatga gtgataatga atatgaaaat cttcttaaaa gtatagctga tttattgaaa
      721 ccatatatag aacaaaagcc taaatcaaat ctaaaactta gaaaactttc aattatatct
      781 tctccacctg tagctgataa tgataaaaca aaataacatg caacccattt ttataaaagg
      841 aggttatata tgaaatttca tgagtttgga aataaaaaca gaccacatat tatgttgatt
      901 catgggggag ggaatgcatg gtggaactat ttgcgacaag cagaagtttt gtctaacaaa
      961 tatcatgtga tacttcctac attggatggt catggagaag aatatgaaac aacatacatt
     1021 tctacagagg atacagcaga taagttgata tcatatatag atgaaaattg cagtggacat
     1081 cttttcgctt tgtgtggggt atcacttggt ggtcaaattg tcatggaact tttatctcga
     1141 aaacctaata ttactaaaaa agcaattatt gatggtagta tttgctaccc aagacctctt
     1201 atggcaaggt tttgtattgc tggtattcga ttttttggag gacttttgtt tagtgagaag
     1261 gcttgtcgct ttcaaattgc tatgatgcca aaattgttac ctgaaaatat gcaatatcca
     1321 gatgaaataa aagcatatta tatgacagat atgccacatg taagaaaaga aacattctat
     1381 aatatgtatc gtacttatat gatgaactat acacttaaag agaatgttaa aaaaaccaca
     1441 gcacaagtaa tgtactggta tggagaaaaa gaaatgaagt gtgtcaaaaa atctgcaaaa
     1501 ctgtttcagt cttatgtgcc ctcttgtgag atttatgaag ctaagagcta taatcatggg
     1561 tatttatcac tttatcttcc aaatgaatgg ttggaaattg cagaaccatt tttccaaaag
     1621 gaataaaggt gttaggtgat tattgtataa ttattgctgt tttttaatat agtaaataaa
     1681 ttaggtataa atataaaaaa gttattttag ttaatatatt agtgaaagct taataggaaa
     1741 attataaata gattaaaggt agcgcctata taaatagttg ctaccttttt ctgtttgtaa
     1801 ataaatgata gataagaagg tttactgaca aatcactgac taaacccaat tttcttacat
     1861 tgaaagcctt aattttactt gttttaaata aatttacaat ttcttgttat aaaatactaa
     1921 attttgttaa caattataat tagcatttaa tttatactgg aggtttatat gattagtgta
     1981 agaacagatt tagctttaga agctagtgaa atgtgtgaaa agtctcaaga aggaagtagt
     2041 attcctggtg taaaaataga aactaaagaa ttagaaaatt gcattgtaac taaagttgaa
     2101 gtaatagaca ggcaaggcgc agagataatg aataaagata taggaaagta tataactctg
     2161 gaaagtaatc ttatgaagtt tgatgatgat gagtcaagag aagaaatgat aagttattta
     2221 aaagaggagt tagtagatat atttggccaa gacaaaaata aaaaaaccct ggtaattggt
     2281 cttggaaata gaaatattac ttctgatgcg ttaggaccaa agagtgtatc aaaaacactt
     2341 gtaactagac atctttttaa aaattataat aaagactatg atgatgattt cactgaggta
     2401 tcagctttaa gcccaggagt tatgggtgtt actggaatag aaactagtga aatagtaaaa
     2461 tcattggttg agaaggttaa gccagataga gtagtagcaa tagatgcatt ggcttcaaga
     2521 aaaatggaga gagtaaactc tactatacag atatcaacag caggaatatc acctggtgga
     2581 ggtgttggca atactagaaa atctctaact aaagaaactt taggcgtgga tgttattgca
     2641 ataggcgttc caacggtagt tgatgcagca actcttacaa tagatgtctt agatatggca
     2701 atagacaatt taatagctca atcagaagaa acagaaagtt tttatgaaat gttgaaaaaa
     2761 cttaaagaag aagaaaaata tcatctaata aaagattcgt tagacccata tgacaagaac
     2821 ttaatagtaa caccaaagga tatagatgat acaatcgaaa atctatctat aataataagt
     2881 gaaggcttaa ataggtcttt acatccaggt agattggtat aaaataagga ggagcaatta
     2941 tgtttaaaaa atgcattaaa gtagtaacct tgacttttat attagtatgc attttaccag
     3001 gaaaatcatt agctttgaat caagatgatt ttttaaagtt tttagtaaat tcatcttatc
     3061 cagaagctaa agtcgaagga aatgatacag aaaataaaaa gaataataaa aataaagaaa
     3121 caagtaagga aaataaggaa gaaagtaaag aagaaaacac taaatctaaa gatgcaagta
     3181 aagtcgataa taaaaaagag agtgaaaaag aatatataaa actttatgtt ggtaaagaaa
     3241 atgttccaga tattgagtca aaaaattcag acacaactga aactaacaca acatctagtt
     3301 cagattataa ggatgattta agagtaacca aagaaaatcc aagaattttg atatatcata
     3361 ctcatggatg tgagacttat tcaaattcac ctgatggaaa ttatcattca agagataaga
     3421 aaaattcagt aatggaagta ggaagtgcat taactagtgc tttagatagc aaaggatggg
     3481 gtgtagtcca tactactaaa taccatgact atccatctta taataactct tatgcaagta
     3541 gcttaaaaac aatacaaagt atattaccta aatataactc agtggatata gcgatagact
     3601 tacatagaga tgctagggat ttaactaatc cagccactaa ggaaaaagac catttaaaat
     3661 atacaactat gataaatgga gagagagtat caaagttctt ctttgttgta ggaggtaaaa
     3721 atacaaatag aaaacaactt agagctttag cagaagatat aactgctttt gctgagaaaa
     3781 agtatcctgg tctagtatct ccaatagtag aaaaagacta tgctagattc aatcagtttg
     3841 cagttaagaa tcatatgtta gtagaaatag ggaataacgc aacaagtgta gaagaatcta
     3901 aggctactac aaagtattta gccgagattt tggatgaata ttttaaacaa aaaaattaga
     3961 gctttaagtt ataattagga gcatgctaaa tgagccgatt agaaaaaaat atagaaagta
     4021 aaagtaaact aagaaaatac aagtatatta tgagaatctt atttttgatt actatgatta
     4081 tatgtacatc agtttgtgta tttatagtgg acagtaatgc aaaaagtatg ctaggaatga
     4141 aacaatatga ttttccaagt attaaatttg atataacaaa atttgatttt gacataccaa
     4201 attttgatat acatgaaatc ataaaaaaat ttaataagta gtaataagtg aataaggttt
     4261 attgattaaa ataagcctta ttttagttat atatttttaa tgtataaaat aaaaattcat
     4321 taactgtatt ttataggatt tactttaagt ttacgatatt atataatatt tagtgttaga
     4381 cttgataatc cacatataat gtggataatt ttgtttagtg ccaattagtt tatattcaaa
     4441 aattttaaat ttggtatata aagagttttt agataatgta aaataataac tataagaata
     4501 atcaagagga gggaatttta aggtggacaa taaacaaagt agaactagaa attttagtat
     4561 aattgcacat atagaccatg gaaagtctac cttagctgat agattaatac aacaaactgg
     4621 gcttgttagt gaaagagaca tgaaaagtca attacttgac aatatggacc ttgaaagaga
     4681 aagaggaatc actataaagc ttcaaaacat aagattaatg tataaagcga aggatggaaa
     4741 tgaatattat ttaaatctta tagatacacc tggacatgta gactttaact atgaggtatc
     4801 aagaagttta gctgcatgtg aaggagcact attagtagtt gatgcagctc aaggtgttga
     4861 ggcacaaact ttagccaatg tttatcttgc tatagaccaa gatttagaaa tattaccaat
     4921 aataaataaa atagatttac caagtgcaag accagaggaa gtaaaaaatg aaatagaaga
     4981 tttaataggg cttgattcaa gtgaagctcc tcttatttca gctaaaactg gtttaaacat
     5041 agaagatgtt ttagaagata ttgtaaaaaa tgttcctcca cctaaaggag ataatgaagc
     5101 tccattaaag gcattaatat tcgattctta ctatgatgct tacaaaggtg ttgtagctta
     5161 tgttagagta tttgaaggaa ctgttaaaaa gggtatgaca ataaaaatga tgaataccaa
     5221 taaaaagttt gaggtaactg aagttggtgt catggctcca ggtcaaactg aacttagtga
     5281 attatcagca ggtgatgttg gttatattgc tgctagtata aaagatataa gaagttgtcg
     5341 tgttggtgat acaataacag attcaaataa tcctacagaa gaacctttac caggatacaa
     5401 aaaagctact ccaatggtat attgtggtat atatccagga gaaggagaaa agtatgagaa
     5461 tgttagagat gctcttgaaa agcttcaagt aaatgatgct gcacttgaat atgaagctga
     5521 gacttcagca gcactaggat ttggttttag atgtggtttc ttaggtcttt tacatatgga
     5581 gataatgcaa gaaagacttg agagagaatt taaccttgat ataattacta cagctccatc
     5641 tgttatatat agagttacaa aaatggatgg agaggttgta atgatacaaa atcctgcaaa
     5701 cttaccagaa ccatctgaga taaagatgat agaagagcct atagtaaaag gagatataat
     5761 agttcctaaa gactatgtgg gtgttgttat ggagctttgc caggaaagac gtggaaatat
     5821 gttaaatatg gaatatatag atgagagaag agtaatgctt cactatgacc ttcctctcaa
     5881 tgaagttgtt tacgatttct ttgatgcttt aaaatcgaga actagaggtt atggttctct
     5941 tgattatgag gttaaaggtt atgtagcatc tacacttgta aaacttgata tattaatcaa
     6001 taaagagcaa gtggatgcac ttagttttat tgtccatgag acacgtgctt tccctagagg
     6061 aaaggcaatg tgtgagaaat taaaaggaga aattccaaga catcagtttg ctataccaat
     6121 acaagctgct gttggtaata aggttattgc aagagaaaca ataagtgctc taagaaaaga
     6181 tgttcttgct aaatgttatg gtggagatat atctcgtaag aagaaacttc ttgaaaaaca
     6241 aaaagaaggt aagaagcgta tgagacaaat tggttctgtt gaagttcctc aaaaagcatt
     6301 tatgtctgtg cttaaattag atgagtaaat ccttataaat ttagataaag atatttaaaa
     6361 gctagagtga ttttagaatt atttctaaat tagtctagct tttttatggt atattttaag
     6421 taaactcata gagaatataa gtaagaatat taaagaagaa taaaaaggtg atatttatga
     6481 ttaatataga aattcctaaa aaagtagact atataattaa agaattagaa aagaatggtt
     6541 atgaagctta tatagttgga ggatgtgtta gagattgttt attagaaaga gttccaaacg
     6601 attgggatat aacaactagt gctagaccag aagtggtagt agaattattt gaaaaaacaa
     6661 ttccaactgg tatacaacat gggactgtaa cagttatgat tgaacatgaa ccatttgaag
     6721 tgacaactta tagaattgat ggaaattata gtgatggtag acatccagat tcaatagaat
     6781 ttacaaataa catagttaag gacttgtcaa gaagagattt tactatcaat tcaattgcat
     6841 acaattcaaa gacaggatta gtcgacccat ttaatggcta tgaagatata caaaataagt
     6901 atatacattg tgttggaaat ccagtagata gatttgaaga agatgcactt agaatgctta
     6961 gagcagttag attttcagca caactcaatt ttaaaatagc tgaaggtact aagcaaagta
     7021 ttcataaaaa agcagatttg ataaaaaatg tttctattga aagaatccag acagagttta
     7081 ataaaatatt agtatctgat tcatctaaat taaacttatt aaaatcaaca ggtttgttga
     7141 aatttataat tcctgaaata tgtgaattag aagatgttac tcaacacaat ccatatcaca
     7201 tctatgatgt acaaaaacat actttaatag ctacagaagc aattgaagat gaactgtatt
     7261 taaaacttac aatgttgttt catgatttag gtaaaaaagt aactaaaaca actgataaaa
     7321 atggtgttga ccatttttat actcatagta gagaatctgt aaagattgca aagaagattt
     7381 tgaaaagact taagtatgat aattatacta ttaataaagt tttaatatta atacaatatc
     7441 atgattatag aatagaacct aaaaggaaga taattaaaaa gttattaaat aaacttgaag
     7501 atgttggatt atttgaagat ttaataaaag ttaattgggc tgatacactt gcaaaaaatc
     7561 caaagtatgc aaaacaaaag atattaaatc ttattgagtg tgaaaaagaa tttaaacata
     7621 taataaatca aaaggagtgc tttaatctta aagatttagc tattaatgga aaagatttga
     7681 tatctatagg tataaaacca ggtaaagata taggatatat tttaaataag atgcttgaaa
     7741 tagtcataaa taatccagag ttaaatgaaa aagaaatact aaaagaaaaa gcattaaata
     7801 tatataca
//
LOCUS       DAMJXI010000116         7711 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.123, whole genome shotgun sequence.
ACCESSION   DAMJXI010000116 DAMJXI010000000
VERSION     DAMJXI010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7711
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.123"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            321..1622
                     /locus_tag="PC465_003541"
     CDS             321..1622
                     /locus_tag="PC465_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2650810.1"
                     /translation="MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIF
                     KIMKELKKENIVIDVATVKSKIDRKSLAIKTSDVTNLITWGQNFGLDGHIKILKENLA
                     RRSINQNCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLE
                     NKKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFI
                     SREMTSEQVFMRNICRVTGVSTRNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKID
                     TISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSRELKNMTLDFNIPVIQ
                     LSQLNDEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVR
                     ASEYRGIKMVDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY"
     gene            1698..1973
                     /locus_tag="PC465_003542"
     CDS             1698..1973
                     /locus_tag="PC465_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2650811.1"
                     /translation="MLELTKIIELLEEHKIEVSIPKELHKYSLLEYLELCQQSGGTYF
                     YIKTLEGALKEARNELMIKLFNGKNYMELARMFEMSVINVRHIVRKK"
     gene            3306..3536
                     /locus_tag="PC465_003543"
     CDS             3306..3536
                     /locus_tag="PC465_003543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2650812.1"
                     /translation="MSNKKKKYANILANECVACGSCIKACPRSAISVPCGISAKINRD
                     LCVGCGICEKICPASVIEIITILKEEEGKCHE"
     gene            3529..4110
                     /locus_tag="PC465_003544"
     CDS             3529..4110
                     /locus_tag="PC465_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2650813.1"
                     /translation="MNNKKHWYDYLWIFSSIYLILGFVNIIFAWIGLICFFVPLAISI
                     VKGNKAYCNKYCGRGQLFNLLGNKLKLSRNRDIPKFIRSKWFRYGFLTFFMVMFANML
                     FSTYLVFEGSRNFKEVVTLLWTIKMPWQWAYHGTLVSPWVVQFAFGFYSVMLTSTVLG
                     LITMILFKPRSWCVYCPMGTMTQMICKAKSKSV"
     gene            complement(4688..5365)
                     /locus_tag="PC465_003545"
     CDS             complement(4688..5365)
                     /locus_tag="PC465_003545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF2650814.1"
                     /translation="MISQNEIDILTHSLPFWDKLTDLQKELLISSANTSHYKKGNPVH
                     CGDSDCIGILIIKSGTVRTYILSDEGREVTLFRLDDGDVCILSASCILKTITFDVYVD
                     AETDCDIIQISSSVFAKLSTENIHAELFSYKLATERFSDVMWAIQQILFMSFDKRLAS
                     FLIDEIAKNGSSTINMTHEQIAKYMGSAREVVSRMLKYFAREGIVSLSRGGIKVLDKD
                     KLRSLTL"
     gene            complement(5554..6918)
                     /locus_tag="PC465_003546"
     CDS             complement(5554..6918)
                     /locus_tag="PC465_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2650815.1"
                     /translation="MKESNKRIELLGSAPISKALLSMGLPTMIGMMITALYNLVDAYF
                     VGGLGTSQMGAISVAFPLGQLVVGLGLLFGNGAASYIARLLGHGDNEKAGKVVSTSIY
                     SSIIVGTLVIIVIMIFLNPILKLLGATKSIMPYAISYASIYVVSSIFNIFNVTMTNIV
                     TSEGAAKTTMCAMLLGALLNMILDPIFIYTFGLGVRGASIATAISQIASTLVYVGYIL
                     SKKSIFSFRINECCFSKEIFSEILKIGIPTLIFQLLTSLAITLTNMEATKYGDSVIAG
                     MGAVTRITSLGSLIVFGFIKGFQPIAGYNFGSKNYDRLHIAIKTSILWTTVFCVVLGL
                     ILILFPKSIISQFTSGDILLIENGSKALRANGFSFMLFGFYTVYSTLFLALGKAKEGG
                     FLGMCRQGVCFIPIILIIPVFYGLNGILYAQPIADLMAAIIAGFMSIRLHKELNLLKI
                     NGMH"
     gene            7046..7567
                     /locus_tag="PC465_003547"
     CDS             7046..7567
                     /locus_tag="PC465_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF2650816.1"
                     /translation="MATIDLIVLGIVKQQPKSAYDIQKAVEYRNISRWVKISTPSIYK
                     KVIQLEQKGYIESKTVKNGKMPEKAVYSLTELGETHFLDLMFDTSSKPINILLDFNAV
                     IVNLNSLTPEKQKLCLNNIEENVQELKKTIEENISIKTEVPETAKAVLEQQLVLAQAL
                     ETWINSLKDNMGN"
BASE COUNT         3006 a          871 c         1328 g         2506 t
ORIGIN      
        1 acgatatatt aataattggc agtaagttat atcaaataag atattactat caagtagtga
       61 attatattga acaatatatt aataattggt agtaaagtat atcaaataag atattgctat
      121 tatgtagtaa attatataaa acaatgtatc agaataaata gtatattaat aatttgtagt
      181 atatcatgac gaataataca gtcataacaa atagtgagtc ataacaaata atgtatttat
      241 aattgataat gtatttataa ttgataatgt atttaaaaat caaaatataa aaacttataa
      301 ggaaagagag attaatttat atgggtaaat caaaagatgt tgaaatagag aagtctattt
      361 taggcacaat tcttttagac aataaattaa gctataagct agatgaatta aatgaaaaca
      421 tgtttatgaa tgatatatgt cttgagatat ttaaaattat gaaagaactt aaaaaagaaa
      481 acatagtgat tgatgtggcc actgtgaaat caaagataga tagaaaatct ctagcaataa
      541 aaacaagtga tgtgactaat ctaattactt ggggtcagaa ttttggtctt gatggtcata
      601 ttaaaatttt aaaagaaaat ttagctagaa gaagcataaa tcaaaattgc caaaaccttt
      661 tacacagcct aaaccttgga gaaaatatcg atacttgtat ttacaaattt gaaagtaata
      721 taaaggagat tttggacaag gatacttatg aaaatgatga tgtaaatagt atagcaggga
      781 aggtgcttga ttttttagaa aacaaaaaag atattggatt taaatttggt ataaaattac
      841 ttgataccac tataggaggt ctttttaaag gagagctaac cacaatagca gctaaatcgg
      901 gggttgggaa gactgctttg gcacttcaaa taatgttaaa ttcatttaag caaggtaaaa
      961 aaactttatt tataagtaga gaaatgacca gtgagcaagt atttatgaga aatatatgca
     1021 gagtaactgg tgtaagtaca aggaatatga aatctaaaga aatagatgaa aatgattgga
     1081 aacttattgt aaatgctata ggtgatttaa gcgaaaataa cttaatttat atcaatgata
     1141 agatagatac aattagtgca attagaaaga ggataaggca ggtaaagcca gatttattaa
     1201 tagtggatta tgtgcaactc cttacatctc agaaaagcat ggataagaga gaaagggaag
     1261 tagctacttt ttcgagagaa cttaaaaata tgactttaga ttttaatata cctgtaatcc
     1321 aattaagtca gttaaatgat gaaatgaaag attcaagacc ttatggagat agacctatga
     1381 gagatagcaa agccatctac cacgatagca acaatgtggt ttatatacat caattaaagg
     1441 ggagtgatta tgaagaagca gtgagagata ttggagaaag tgaggaggca gttagagcat
     1501 cagaatacag gggaattaag atggttgatt taatagttgc gaagtgtaga gatggacaga
     1561 ctaggcataa gcatttttgt tactttgggg ataagttaca ttttcaagaa ctaaattatt
     1621 aggtcaataa agtagtaata acaagcttat taaaagtcgg ggaatagcaa atagattata
     1681 aaatatgagg tgaaaatatg ttggaattaa caaaaattat agaattactt gaagaacaca
     1741 agatagaagt aagtattcca aaggagttac ataagtatag tttattggaa taccttgaat
     1801 tgtgtcaaca aagtggggga acatattttt atattaaaac actggaaggg gctttaaaag
     1861 aggctagaaa tgagcttatg attaaattgt ttaatgggaa aaattatatg gaattagcga
     1921 ggatgtttga aatgagtgtt attaatgtca ggcatattgt tagaaaaaaa tagatatttt
     1981 tggagaatac aagtgtgata tacttctgaa atagaagtta ttatagttga aataaaattg
     2041 tggttaataa attaaagttg tgtataagtt taagattata gaggagtata agtgtgatta
     2101 acagcatgat tttgtgaata aaattgagga tatatatgag ttaaatgtgt gattaataag
     2161 gtaaggttgt gtataagatt atgagtattt aaaaggaggg gctataatta atagtgtaga
     2221 gttgtgtgtt tgcttaagat tatataataa tttaatagat taaactatac taataaggta
     2281 aaatcgtgtg tttagttaaa gcttattata aaatcttgat atgtgattaa tgatgcaata
     2341 tgtgaataaa gttaagatta taatagattt aacctgtggc taatagaata aaattgtgaa
     2401 taaagttaag attataatag gtttaatctg tgactaatag agtaagagtg taaatagaga
     2461 taaacttcaa tatgagctta acctatgatt aatagagtaa gagtgtaaat agagataaac
     2521 ttcaatatgg gtttaacttg tgattaatag agtagggtgt aactaaagat aaacttcaat
     2581 atgagtttaa cttgtgatta atagagtaag gtgcaactaa agataaactt caatatgagc
     2641 ttaacctatg attaatagag taagagtgta actaaagata aacttcaata tgggtttaac
     2701 ttgtggttaa tagagtaaga gtgtaaatag agataaactt caatatgggc ttaacttgtg
     2761 attaatagag taagagtgta actaaagata aacttcaata tgagcttaac ctatgattaa
     2821 tagagtaaga atgtaaatag agataaactt caatatgagt ttaacttgtg gctaatagag
     2881 taagagtgta aatagagata aacttcaata tgggtttaac ctgtggttaa tagagtaggg
     2941 tgtaactaaa gataaacttc aatatgagtt taacttgtgg ctaatagaat aagattgtga
     3001 ataaagttat agttttagat gggtattaac ctgttactaa tagaatatga ttaggtgtaa
     3061 aattatagag ctgtataaga aaatattata gatatattaa atattagata ataaatattt
     3121 atatagatac acaaaagaaa aggcgatatg aagctaaact taatgacttc atatcgtttt
     3181 ttatttgaaa ctcctttgta tttagagtgt gatttttaat attgaggttt tatgtgatta
     3241 agtcacagat aaaaagtaag tatcttgata taattcttat agattaataa tatagggagg
     3301 ttattatgtc taataaaaaa aagaagtatg caaatatttt agcaaatgag tgcgttgctt
     3361 gtggtagctg tataaaagca tgtccaagaa gtgctatctc agttccatgt ggcattagtg
     3421 caaaaattaa tagagattta tgtgttggat gtgggatttg tgaaaagata tgtccagcat
     3481 ctgtaattga gattataaca atattaaaag aggaagaagg taagtgtcat gaataataaa
     3541 aaacattggt atgactattt atggattttt tcttcaatat atttgatatt gggatttgta
     3601 aatattattt tcgcttggat tgggctaatt tgtttctttg ttccactagc tatttctatt
     3661 gttaagggaa ataaagctta ctgtaataag tattgtggaa gagggcaact gtttaatttg
     3721 cttggaaata aattgaagct gtcaagaaat agagatattc ctaaatttat tagaagtaag
     3781 tggtttagat atgggttttt gacatttttt atggtaatgt ttgctaatat gcttttttca
     3841 acttatttag tgtttgaagg aagtagaaat tttaaagaag tagtgacttt gttgtggact
     3901 ataaaaatgc cttggcaatg ggcgtatcat ggaactttag tttcaccttg ggtggtacag
     3961 tttgcatttg gtttttatag tgttatgctt acatcaactg ttcttggttt gattactatg
     4021 atattgttta aacctcgttc atggtgtgtt tattgcccta tgggtactat gactcagatg
     4081 atatgtaagg caaagagtaa gtctgtatag aaaggcctta tgtgatattt acagttttgt
     4141 tcaagtagag atgagtagta ggtttgaata tatatgacaa atatatgagt ataggggcat
     4201 agatttagtt tgtgtaaggc aaactgattt atgcttcttt tttatgtctt agattattgg
     4261 ctaagtagaa acaatgaatt tagatattaa gaattattca gttatttgaa gaaaatagaa
     4321 taataattaa cattatatga atggatattc attacatata agcagttaat agcaagattt
     4381 atttaatatg aaataggtca agtatttaaa ctaaataagg tcatgacaat taatataagt
     4441 atagatataa aaagattaga agttataact tataaaaggt attctatata agtagtatgt
     4501 ggaaaatagt caaattaact tattagaaac aaaaaatata cataaaaaat aaatgtaaat
     4561 atcaaataag atactatata aaaatagata taagtatctt ttttattatt gaaattatga
     4621 aaatatattt tattttacac aaaaaagagt gcctcatgaa ctaaaaagtt cattttgaga
     4681 cacactttta cagtgtcaaa gaacgaagtt tatccttatc caatactttt ataccaccac
     4741 gagataaaga cacaatacct tctctagcaa aatatttcaa cattctcgat acaacttctc
     4801 tggcactacc catatactta gcaatttgct catgagtcat atttatagtg ctactgccat
     4861 ttttagctat ctcatcaatt aaaaaagatg ccaaacgctt atcaaaactc ataaaaagaa
     4921 tttgttgtat agcccacata acatcagaaa aacgttcggt agctaattta tatgaaaata
     4981 actctgcatg aatattttct gtagataatt ttgcaaaaac agaggaacta atctgtataa
     5041 tatcgcagtc cgtttcagca tctacataga catcaaaagt tattgttttt agaatacagg
     5101 aagctgataa aatacataca tctccatcat caagtcggaa cagtgtaacc tctcgacctt
     5161 catctgaaag tatgtatgta cgcactgttc cagactttat aatcaaaata ccaatacagt
     5221 cactatcacc acaatgtact ggattccctt ttttgtaatg cgaggtattt gctgaagaaa
     5281 ttaataattc tttttgtaag tcagtaagtt tatcccaaaa aggcaagcta tgtgtaagta
     5341 tatcaatttc attttgtgaa atcatacaat atctcctttc ttaaattgtt ataatcccat
     5401 gatacaagtg aatagataaa ttgacaagta gtttgttaag aggattattt agtcagatag
     5461 taatagtatg atttatgtag aaaaaatatg ataatatgta ttcttgctat taatgagaaa
     5521 gtaatatgtt ttgatgatag taggtttgta taactaatgc ataccgttta tttttaaaag
     5581 attaagttcc ttatgtaacc ttatagacat aaaaccagca attatagcag ccatcaaatc
     5641 ggctattggt tgtgcatata agataccatt taacccatag aatacaggaa taatcaaaat
     5701 tatagggata aaacagacac cttgtctaca catacctaaa aatccacctt cctttgcttt
     5761 tcctagtgcg aggaataatg tagaatacac tgtatagaat ccaaatagca taaatgaaaa
     5821 cccatttgcc ctaagagctt tactaccatt ttctattaat aaaatgtcac cacttgtaaa
     5881 ttgtgaaatt atagattttg ggaagagtat caatataaga ccaagcacta cacaaaatac
     5941 tgtagtccat aatatggaag tttttattgc tatatgtaat ctatcgtagt tctttgaacc
     6001 aaaattataa ccagcaattg gttggaaacc ttttataaaa ccaaatacaa taagactacc
     6061 taaagatgtt attcgtgtta cagcacccat tccagctatc acagaatcac catactttgt
     6121 agcctccata ttagttaatg taatggcaag actagtcaat aattgaaata ttaaggtagg
     6181 tatgccaatt tttaggattt ctgaaaaaat ttcttttgaa aaacagcatt cgttaattct
     6241 aaaactaaat atacttttct tgcttaaaat atatcctaca taaacaagtg ttgaagcaat
     6301 ctgtgagata gctgttgcaa tagaagcacc ccttaccccc agaccaaaag tataaatgaa
     6361 tatcgggtct aaaatcatat taagcaaagc acctaataac atagcacaca tagttgtttt
     6421 agcagctcct tcacttgtga caatattagt catagtgaca ttgaatatat taaaaataga
     6481 tgacacgaca taaatgctag cataagatat tgcataaggc ataatacttt ttgtagctcc
     6541 taacaatttt aaaattggat tgagaaaaat cataatcaca ataataacta atgtacccac
     6601 tataatacta ctgtaaatag atgtacttac cacttttcct gctttttcat tatcaccatg
     6661 ccctaaaagt ctggcaatat atgaagcagc tccatttcca aacaataatc ctaatcccac
     6721 aacaagctga cctaatggaa atgcaacgga tatagctccc atttgacttg ttccaagtcc
     6781 acccacaaag tatgcatcaa ccaaattgta taatgcagtt atcatcatac ctatcatggt
     6841 aggtaatccc atagataaca atgcttttga gattggggca gaccctaata attcaattct
     6901 tttgttactt tctttcatac ttaacactcc ccttctattg acattaagtc taaattataa
     6961 tactataaat tatagtaagt atggaaaata gtactataat ttatagtatt tgtcaatagt
     7021 aagaaaacta aaggagatga tttttatggc tacaatagat ttaattgtat tgggaatagt
     7081 aaagcaacaa cccaagagtg cttatgatat tcaaaaggca gtggaataca ggaatatatc
     7141 acgttgggtt aaaataagta caccatcaat ttataaaaaa gtaattcaat tagaacaaaa
     7201 gggatatatt gaaagtaaaa ctgtgaagaa tggaaaaatg ccagaaaaag cagtttattc
     7261 attaactgaa ttaggtgaga cacatttttt agatttaatg tttgatacat ctagcaaacc
     7321 aataaatatt cttttagatt ttaatgctgt tatagtaaat ttaaatagcc ttacaccaga
     7381 aaaacagaaa ttatgtctca ataatattga agagaatgtt caagagttaa agaaaactat
     7441 tgaggaaaat ataagtataa agacagaagt accagagaca gcaaaagcag tgttggagca
     7501 acagttggtg ctagcacaag cattggaaac ctggataaat tctttaaaag ataatatggg
     7561 aaattagaat tagagaagct aacttaataa tcattaaaca aaaaccagca tatttaataa
     7621 tgagatatta gaaaaaataa aacaaatgat ataaactgaa aagtatattt aaaataaagc
     7681 tcacttaatt gagggagaat gttaaacttt t
//
LOCUS       DAMJXI010000117         7704 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.124, whole genome shotgun sequence.
ACCESSION   DAMJXI010000117 DAMJXI010000000
VERSION     DAMJXI010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7704
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.124"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(255..920)
                     /locus_tag="PC465_003548"
     CDS             complement(255..920)
                     /locus_tag="PC465_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HDF2650817.1"
                     /translation="MKKDTSHIIKRAEHFQVILIGEGLMVGAVAGLIVLLYRILLGQA
                     GTWLSQILKFVEGSTIKIIAWFAVLAVLAWIVSKLVDWEPMISGSGIPQLEGEMTGKI
                     KQVWWRVLPTKFIGGFLSLMGGLALGREGPSIQLGAMVGKGISRALDRGKTEEKFLLT
                     CGASAGLSAAFHAPLAGVMFSLEEVHKNFSVSVLISVMTASLTADYISANFLGMESVF
                     QFD"
     gene            complement(1080..1616)
                     /locus_tag="PC465_003549"
     CDS             complement(1080..1616)
                     /locus_tag="PC465_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HDF2650818.1"
                     /translation="MIGLKCGMVKLLEHQMIWDKSAKDVIILLKSIWDKTAIDIQHIG
                     STSIPSISAKPIIDIVVGVASLEEAKLYLERLEQCGIVFRGQDVPKQLLFAMGDFEKN
                     TRTHHIHVVEWNSVAWNNYINFRDYLNTFTDKAKLYDSHKQKLALQFEDNRKIYTQRK
                     QELINILLEEARLWRINT"
     gene            complement(1689..2102)
                     /locus_tag="PC465_003550"
     CDS             complement(1689..2102)
                     /locus_tag="PC465_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HDF2650819.1"
                     /translation="MKMPKESIDTIMFAPCGMNCMVCYKHCYHKKPCAGCLNGDTGKP
                     EHCRKCKIKDCVCQKGLFYCFECFNFPCKLIKNLEKSYNKRYQASLMENSKFVQQYGL
                     EKFMQKQKERYTCSKCGGIIFIHDRECSECQEKVK"
     gene            2595..3233
                     /locus_tag="PC465_003551"
     CDS             2595..3233
                     /locus_tag="PC465_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="HDF2650820.1"
                     /translation="MDEKILELLQEMQGNISNMQGSISGIEGTISDMQSNINGIEGTI
                     SDMQSNINGIEGTISSMQGNINGIENTISGMQGTIGDMQGSISGMNGTISDMQGSISS
                     MDGTINSMQDSITDMQVEIKEVNSRLDNMEPDIKDLKTGQVETSSRLDTIQSDVTEIK
                     SDVKINRNTLDTVIKHTSSLVKDTSDIKNDLNNIEIVTSKNSNDIAKLKSVK"
     gene            complement(3841..4020)
                     /locus_tag="PC465_003552"
     CDS             complement(3841..4020)
                     /locus_tag="PC465_003552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2650821.1"
                     /translation="MLQTGKQGADKKYLDNMFFVKGYVEELLFLDNSYDIVFSCIVFH
                     HCTNVQNIFCIFWKW"
     gene            complement(4246..4779)
                     /locus_tag="PC465_003553"
     CDS             complement(4246..4779)
                     /locus_tag="PC465_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDF2650822.1"
                     /translation="MQYISYYHSPIGNILLASDNIGLTGLWFENQKYYAYNLDQEHQE
                     KELPIFEQTKKWLDIYFSGKEPNFTPSLHMVGTPFQITVWKILQQIPYGKTITYGEIA
                     YKVAQQKGISKMSAQAIGGAVGHNGISIIVPCHRVVGTNGSLTGYAGGIDRKIKLLSL
                     EKVSVQHYFIPKKGSAL"
     gene            5415..5734
                     /locus_tag="PC465_003554"
                     /pseudo
     CDS             5415..5734
                     /locus_tag="PC465_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429539.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(6364..6936)
                     /locus_tag="PC465_003555"
     CDS             complement(6364..6936)
                     /locus_tag="PC465_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF2650823.1"
                     /translation="MWIYQKTLEHPVNIRQADPRMAKYIMTQLGGPNGELAAATRYLQ
                     QRYTMPTGKSRALLTDIGTEEMAHVEIISSVLYQLIGNCTPEELKAAGLGSNYANFGH
                     GLQPVDSNGVNFTTSYINVFGDSVTDLHEDMAAEQKALATYYQLINLTDDPDLKDILR
                     FLGEREVVHYQRFGEALMDVYEFTECKHQF"
     gene            complement(6998..7261)
                     /locus_tag="PC465_003556"
     CDS             complement(6998..7261)
                     /locus_tag="PC465_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HDF2650824.1"
                     /translation="MSLNRRELLERISEYQFACIELNLYLDNNPRDKKALDSYNRYCD
                     KFTQAVCDYESKYGALTNFGYESSEYPWSWISEPWPWDKSFYK"
     gene            complement(7261..7482)
                     /locus_tag="PC465_003557"
     CDS             complement(7261..7482)
                     /locus_tag="PC465_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HDF2650825.1"
                     /translation="MGYLKEDKQDYCCEFARPYINRQIYDDTYNPKTALKRGTLFPEL
                     DLIESNNYNDWLYANPKNRVRAKKGGNMY"
BASE COUNT         2689 a         1310 c          918 g         2787 t
ORIGIN      
        1 ttacctgctg attgcccatt ttaaagtact taggatttaa ccttatacca tctaaccaat
       61 tttttctact ttcgtaactt tcacacttag gtttatttca tccttatgtt ttagtttggt
      121 tagctttagg ggtttccagc aattcaagta gtattggata ggttctatcc tatctctaca
      181 tataggtttc cctatatgct gactatttta gctactaact catgactaaa gtcacaagtg
      241 tgcgtagcta ttttttaatc aaactggaat acagactcca ttcctaggaa attggctgaa
      301 atatagtctg ctgtcaaaga tgctgtcatc acagaaatta aaacagatac tgaaaagttt
      361 ttatggactt cttcaagtga aaacataaca cccgccagtg gtgcatgaaa ggctgctgat
      421 aatccagcac ttgccccaca ggttaacagg aatttttcct ctgtcttccc tcggtcaaga
      481 gctctagaaa tacctttacc taccatagca ccaagctgaa tggaaggacc ttcccttccc
      541 aaagcaagac cacccatgag tgataagaat cctccaataa attttgttgg caacactcgc
      601 caccatactt gttttatttt ccctgtcatt tccccctcaa gctgagggat accacttcca
      661 gaaatcattg gctcccagtc caccaacttt gatacaatcc atgcaagtac tgcaagtact
      721 gcaaaccaag ctattatttt tattgtagaa ccttctacaa attttaaaat ttggctaagc
      781 caagtaccag cctgccctaa aagtatcctg tataaaagca caatcaaacc agccacagcc
      841 ccaaccataa gtccttcacc aatcaaaatt acctgaaagt gctctgcccg tttgataata
      901 tgagatgtat cctttttcat actattcctc cttcatccaa taattctaca caatctgaat
      961 ctccaatgac taaagtcatg agtgtgtaca gatatttttt aatcaacaaa aatagatttt
     1021 tacttactaa atataagaaa ataattgctc aatttctcaa taaatgtgaa tttattcttt
     1081 taggtattta ttctccacag tcgtgcttct tccagcaaaa tatttattaa ttcttgcttt
     1141 ctctgtgtat agattttacg attgtcctca aactgtaatg ctaatttttg tttatgacta
     1201 tcatagagtt ttgctttgtc tgtaaaagta tttagataat ctcgaaaatt gatataatta
     1261 ttccatgcaa cactattcca ttcaacaaca tgaatatggt gagtacgagt atttttctca
     1321 aaatctccca tagcaaaaag taattgtttt ggtacatcct gacctcgaaa aacgattcca
     1381 cattgctcta acctttcgag gtataattta gcttcctcta aagaagcaac acctacaaca
     1441 atatcaataa taggctttgc gctaatactg ggaatagaag tgcttccaat gtgttgaata
     1501 tcaatagcag tcttatccca tatacttttc aataatataa tgacatcttt tgcactttta
     1561 tcccatatca tctgatgttc caataattta accataccac attttaaacc tatcactata
     1621 taccacctca atataatcca cctttatata tattacaatt ttttctatct tgataaacag
     1681 tgatttagct atttcacttt ttcttgacac tcgctacatt ctctatcatg aataaatata
     1741 attcctccac atttagaaca agtatatctc tccttctgct tttgcataaa cttctctaaa
     1801 ccgtactgct gaacaaattt actattttcc ataaggcttg cttgatatct cttgttataa
     1861 cttttttcaa gattttttat gagtttacaa ggaaaattga aacattcaaa acaataaaac
     1921 aacccttttt gacagacaca atcctttatt ttacacttac ggcagtgttc tggctttcct
     1981 gtatcgccat tcaaacaacc agcacatggc tttttgtgat aacaatgctt atagcaaacc
     2041 atacaattca ttccacaagg agcaaacata atcgtatcaa tactctcttt tggcattttc
     2101 ataacatttt actcctttca aaaatccaat ttgtcgaatt gttatatatt catattgtaa
     2161 cataaaaaat agctaaaaaa ttcatgcact ttcattgcca ataaattttc aaggaaatat
     2221 gaaagtttaa aactaagaat aaaaagagat aaaaaggaag ctactaatca aaatattcaa
     2281 atacaagtaa tcaatataaa taacttaagg tatatttaaa agtatatgat attaccagca
     2341 gttttaaata caaatataac cacacatgcc tcaaaaacac ttattacagt atcttagaaa
     2401 cttagacaat acataagatt cattaataaa aaagttctca atatagtcat taataaaaac
     2461 gttctcaata tagatatatt taaccatgtt ttgaatagca gataattata tgattaaaaa
     2521 ttaaatatga catagcgttt gtggaatata acacctaaat tatgttataa taataaaaca
     2581 ggagtgtgat agtgatggat gaaaaaatat tagagttatt acaggaaatg caaggtaata
     2641 ttagtaatat gcaaggtagt atcagtggta tcgaaggcac tattagcgat atgcaaagca
     2701 atatcaatgg tatcgaaggc actattagcg atatgcaaag caatatcaat ggtatcgaag
     2761 gcactattag tagtatgcaa ggcaatatca atggtatcga aaacactatt agtggtatgc
     2821 aaggcactat tggcgatatg caaggtagta tcagtggtat gaatggcact attagcgata
     2881 tgcaaggcag tatcagtagt atggatggca ctattaatag tatgcaagac agtattactg
     2941 atatgcaagt tgaaattaaa gaagtcaata gtaggttaga caatatggaa cctgatatta
     3001 aagacttaaa aactggacaa gttgaaacta gtagtagact tgatactatt cagagtgatg
     3061 ttacagaaat taagtcagat gtaaaaatta acagaaatac attagataca gtgattaaac
     3121 atacctcttc attagtaaaa gatacatcag atattaaaaa tgatttaaat aatatagaga
     3181 tagtcacatc taagaattcg aatgatattg ctaaattaaa atcagttaaa taatatacta
     3241 tagtaaaaaa tacctgaaaa tttcacatac ttctttaaag ttataccaaa ttttatacag
     3301 aaatactgat tatccgacaa cacactttac ttataaataa tttattaaaa aaatactcat
     3361 tttatcctaa aattaacacg actaaatgag tcttgatata ataataaaaa ataagggaga
     3421 ttggacacta aaaagttgtg tatctccctt atatcctata atatagttat ataatttttc
     3481 agcctaaaat aaaagtccat ctttgattaa aacacatccc cttatcactt ataaaaggat
     3541 aaaatcttgt tttcattttt ccatttatat cttcttgctt aagagtaata attttttctt
     3601 ttgatacttt aagtgtttgg ttaaatttaa ccaatcgact aagttttgtt caacatctat
     3661 ttttcatatt ttccaatact taatctattt tttataaata attctttcat ttctaactca
     3721 cttacatttt ttacataaaa cgaagcatat aaatttcaac cttatcttgt atggttctta
     3781 atacttaatg agtagcttaa gtatcaaaca ttataaattt tccccttaca tttaacactc
     3841 ttaccatttc caaaatatac aaaatatatt ttgaacattt gtacaatgat gaaatacaat
     3901 acatgaaaat acaatatcat aactgttgtc taaaaataga agttcttcaa cataaccttt
     3961 cacaaaaaac atattatcta aatatttttt gtctgctcct tgttttcctg tttgtagcat
     4021 ataaattact gcatctaaac atataactac tcacacgaaa aatgaaaata aacttccaaa
     4081 atacaagctc taaaaactac ctctaaagtt gtataatgtt tactaggaat aaggttgtat
     4141 aacatatagt ttaaataatc attttttaaa attgcaagtt attgctttca aaattagatg
     4201 tttgtatatc aaataaatga ttaagaattt ctaaatttaa tggctttata atgcactccc
     4261 tttctttggg ataaaataat gttgcacaga tactttttct aaagataaca attttatttt
     4321 tctatcaatt ccaccagcat acccagtcaa actcccattt gttcctacaa cacgatgaca
     4381 tggaacaata atagagattc cattatgccc tactgcacca ccgattgctt gtgctgacat
     4441 tttagatatt cctttttgtt gagcaacttt atatgcaatt tctccataag tgattgtttt
     4501 accatatggt atttgttgta aaattttcca cactgtaatc tgaaaaggag tacctaccat
     4561 atggagtgat ggtgtaaaat tgggttcttt tcccgaaaaa taaatatcta accatttctt
     4621 tgtctgctcg aaaattggca attctttttc ttgatgttct tggtcaagat tataagcata
     4681 atacttttga ttctcaaacc aaagaccagt taacccaata ttatctgatg ctaaaagaat
     4741 atttccaatt ggactatggt aatagctaat atattgcata caattcctcc ttatattctg
     4801 aaaacttcac tcaaatcatt agacacttct tttctatcta ccattatgta aaaacatact
     4861 aatataattt ccttctaact acactttcgt tataatatct atcctcatat catattagtt
     4921 ttatatttac ctgcatctgt tcatcctttt ttccctttcc ttttgatgaa tataaaattc
     4981 atacatttaa gcttcctact gtattaactt ttatagaagt gtatattata attttatcac
     5041 taaatagacc aaaaaaatat cgatataaca tcaagtaata tcataatact ttcaaatggg
     5101 aaaagtaaga ataggctgta aaaaagaaaa gtatttttat gttagaaatc cagtaaaatc
     5161 gttagtaaat agaataacag aaaacgaaca attcgctatt tatcatttta cacataaata
     5221 taattggcgc aataaagtgt tttctattct acaacgatta ataaggttag aaaaaagtaa
     5281 aaatgaactg tatatgtatg aagcattagt ttctgtttct ttcctttggc ttattatgat
     5341 aaaaaatatt gttttgccac caataaaaca caaaaatata attaatatcc atatgcaaaa
     5401 aattttacgt tatattgaaa aatactattg ttttacatta tattgaaggg tactattgtg
     5461 aaaacttaat tttggagtac tatcaagcag tgataatatc aataaatcag agtgttccag
     5521 aggatttgaa ctaagtttaa atactatacc ttgtaaatat tttactgagt tttgtttact
     5581 aaaagcaact caatttctaa aaggcacaaa tgagctaata agtgacattg ctataaaagt
     5641 tgtttttcat caaataatct attttagtaa atgttttaaa gaaaaaacgg gatattctcc
     5701 aaaagtgtac agaaatataa aaaaagagat atgatttttt atttcttttg attatccaaa
     5761 gagtaaataa aaaatattgt aaaaaactta ctaacaacgg caatgctttg aactatggta
     5821 atactttgaa cttttgattg gacttttttt gctaaaataa tatatttaaa tagcaaagta
     5881 atctgtttaa tcaataaaaa ataagagata aaagaaatca actaaaactt ttacctctta
     5941 ttttgatagt ttattagagc taatatttac actcttttta tttttgatac ttcattaaaa
     6001 atgatgctta ttctcttttc atttttaata cttcattaga acttatgctt attctctttt
     6061 catttttaat acttcattag aacttatgct tattctcttt tcacttttaa ttcttcatta
     6121 gaacttattc ttactctcca ttcactttta attcttcatt agaacttatt cttactctcc
     6181 attcactttt aattcttcat tagaacttat tcttactctc cattcacttt taattcttca
     6241 ttaaaaatga tgcttattct ccattcactt ttgatacttc attaaaaatg atgcttattc
     6301 tctgttcact tttaattctt tattaaaact gatgcttact ctccattcac ttttaattat
     6361 tcattaaaac tgatgcttgc actctgtaaa ctcataaaca tccattaatg cttcaccaaa
     6421 tctttgatag tgaactactt ccctctcacc caaaaatctc aatatatctt tcaaatcagg
     6481 gtcatcagtt aaatttatta attgatagta cgtagccaat gctttttgtt cagcagccat
     6541 atcctcatgt aaatcagtta ccgaatcgcc aaagacatta atataacttg tagtaaagtt
     6601 tactccatta gaatctactg gctgaagacc atgtccaaaa ttagcataat tactaccaag
     6661 tccagcagcc ttaagctctt ctggagtaca attgcctatt aattgatata acactgaaga
     6721 aattatctca acatgagcca tttcctctgt acctatatca gttaaaagtg cacgagattt
     6781 tccagttggc atagtatatc tttgttgaag atatctagtt gcagctgcca actcaccatt
     6841 aggtcctccc aactgagtca tgatatattt tgccattcta gggtctgctt gtcttatgtt
     6901 aactggatgt tccagtgttt tttgataaat ccacatatta tcttactcct ccttaatata
     6961 tatttaataa taaatctaat tttaaagttt aataatttta tttataaaat gatttgtccc
     7021 atggccaagg ttcagatatc catgaccaag gatattcact tgattcatat ccaaaattag
     7081 ttaatgctcc atatttagat tcataatcac acacagcttg tgtaaattta tcgcagtatc
     7141 tgttgtatga atcaagagct ttcttatccc ttggattgtt atctaaatat aaatttaatt
     7201 ctatacaggc aaattgatat tctgaaattc tctctaaaag ttctcttcta tttaatgaca
     7261 ttagtacatg ttaccccctt ttttagctct aactctattt ttaggatttg catatagcca
     7321 atcattatag ttatttgact ctattaaatc taattcagga aataaagtac ctctttttaa
     7381 tgctgttttt ggattgtatg tgtcatcata aatttgacga ttgatgtatg gtctagcaaa
     7441 ttcacaacaa tagtcttgtt tatcctcttt taaatatccc attaattatc ctccttaatt
     7501 tttagaattt taaaatagca ttatttttaa aaattgtata ctggttctat attataactg
     7561 gtagttttaa taggtcttta ataagattaa atgattaaat aagtatcttt ttttcttatt
     7621 ttacctctaa aatttttcta attaatcttt cataaatatc tattttaaat aaataatata
     7681 gagtttatac aattttttat agct
//
LOCUS       DAMJXI010000118         7371 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.125, whole genome shotgun sequence.
ACCESSION   DAMJXI010000118 DAMJXI010000000
VERSION     DAMJXI010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7371
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.125"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            648..1157
                     /locus_tag="PC465_003558"
     CDS             648..1157
                     /locus_tag="PC465_003558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009528606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HDF2650826.1"
                     /translation="MSKELAINEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLD
                     LVQISPNANPPVCKIMDYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTK
                     ANNAIKFLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNN
                     MVVIIDPKK"
     gene            1185..1379
                     /gene="rpmI"
                     /locus_tag="PC465_003559"
     CDS             1185..1379
                     /gene="rpmI"
                     /locus_tag="PC465_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HDF2650827.1"
                     /translation="MPKMKTHRGAAKRLKKTGTGKLKRAKAFKKHILTKKSAKTKMNL
                     RKSTLVSDGDAKRIAQLLPY"
     gene            1435..1791
                     /gene="rplT"
                     /locus_tag="PC465_003560"
     CDS             1435..1791
                     /gene="rplT"
                     /locus_tag="PC465_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HDF2650828.1"
                     /translation="MARVKKAMNARKKHKKILKLAKGFRGSRSKLYRPANTFVMKALK
                     NAYIGRKLKKRDFRKLWIQRINAAARMNGISYSRLMNGLKLSGVEVNRKMLSEMAIQD
                     PEGFAKLAEVAKAKLA"
     gene            2101..2646
                     /locus_tag="PC465_003561"
     CDS             2101..2646
                     /locus_tag="PC465_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650829.1"
                     /translation="MNEKLMDCFVNPIKCKLLIEIFSNNRTTAKQLGEKFQDISKATL
                     YRYLNKMLKDDIIKVVEENKIRGTVEKVYAMKLDIADDVNKIIDENSGEEYAQLFTQY
                     MMGFLREFYEYAERKEKDILKDGSGFSVCPVYASIDEIVEVSKKIASILEPLRNNSHE
                     EGRRMHSIGVIITPPKEDEGK"
     gene            2633..2806
                     /locus_tag="PC465_003562"
     CDS             2633..2806
                     /locus_tag="PC465_003562"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650830.1"
                     /translation="MKGNKSDLHGVEPIYTENRFMIYICIQSKVSLLGLYFIVPFHPM
                     TWSGTMKFFNFSY"
     gene            3081..5006
                     /locus_tag="PC465_003563"
     CDS             3081..5006
                     /locus_tag="PC465_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2650831.1"
                     /translation="MKIKFVIMPLVIFLMVLFVGCQSTKDTEVKAKDTEIKILGTGDL
                     HSILTDSMVSYINEEREKNKNLLMVDAGDFYGTQSREMWEWSSGKKLINIKRNGRAEY
                     DDIIKSSKDEVPIVKDMAKLKYDAVVLGDNEFISNDKQSLDKLVSDFKNNNMPLVSAN
                     IYEQSGENYVQPYVMKNIKTDEGNVKVGILGLTIKEVGETLGLEDFEKDKKARELGEQ
                     ADYKGKLYANDLVEDAKKWIKVMEKESPDIIVAVVHSGEEPKTDRNPGNRIKELATTV
                     DGIDAIVAGHTHEKIDEHKYKNKSGDEVIVTQPGWHGDRVSEINFKLNKENGKWDIKE
                     KSSKLKIIDKEVSIVATADLHSHFSDELTVDLVNERSNPIEPVVVDAGDFLDPQTDEM
                     TQWYKEWKSIRDNNSDKTISRCPMVMDMNQGMYDAVVLGNHEFVSEKDEFWSDERLLD
                     AVIEDFEQVAISVLSANIYRQSGKNYVKPYIIKDVETSEGNVKVGILGLTIKEVGKGL
                     KNVNLQEQFQYKDKLYANDLVEDAKKWVKVMKKKKPDIIVAVVHSGEEPKNPKHPGNR
                     IKELATTVDGIDAIVASHTHEKIDEHEYKNKSGEKVIVTQPGEHGKYYSKITFKVNKE
                     KGSWTINDKFSKTIEVE"
     gene            5407..7311
                     /locus_tag="PC465_003564"
     CDS             5407..7311
                     /locus_tag="PC465_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2650832.1"
                     /translation="MKIKFIIVASIIFLIVLLVGCQSTKDTEINVLATSDLHSIIPDN
                     LISYVEEERKYDENLLMVDAGDFFDMQSGEMNKWFTGQKLVRFKDGIPEYKKIAEPRE
                     GEVPLAKKMAKLKYDAVTFGNHEFVSNDKQSLDKLVSDFKNNNIPLVSANVYEQSGEN
                     YVKPYVMKNINTDKGTVKVGILGLTIKEVGERSRFKSFEQDKKARELGEQPQYKGKLY
                     ANDLVEDANKWVNVMEKKEKPDIIVAIVHSGEEPKNPKNPGNRIKELATTVEGIDAIV
                     AGHTHEKIEQHTYKNNSGEEVIVTQPGAHGNSISKINFKLDKKNDKWFIKDKYSELKV
                     FGKEVNIITTSGLNPKFSDEMAVNLFNERDRDVQPIFIDTGDFLNTNTKEMTKWAKEW
                     QYNENKGIYKKINEWPIVYLGYDAVVLGSHEFTEDKETFEEKKSTLDYIIENFEEMKI
                     PVLSANIYDESGENYVKPYIIHNVETREGNIKVGVLGLTTTDKDEEDLSNSSLSKDSK
                     TSKIPEETGKLYTNNLVKDASEWVKVMQKESPDVIVAVVHSDNNSTLKNPSSEVKKLA
                     MSVDGIDAIVVGHTKNKVEEHIYKNKSGDEVIVTQSGEDCYLKISLELRKENGKWNII
                     NKYSKAIKMK"
BASE COUNT         3092 a          720 c         1395 g         2164 t
ORIGIN      
        1 ttatgtagta tagtagcata ttagaatata atgtaggact tgttatgtag tatagtaaca
       61 tattagaata taatgtagga tttgttatgt agtatagtag catattagaa tataatgtag
      121 gacttgttat gtagtatagt aacatattag aatataatgt aggatttgtt atgtagtata
      181 atagtatatt agagtacaat atagaatttg ttatgtagta tagtagtata ttagaataca
      241 atatagaatt tgttgggtag tatagtgtta tattagaata caatatagga tttgttatgt
      301 agaatatata gagtcatgta gaatatacat atataaaagg attttgggta taaatttaaa
      361 aattaatagc aaaatgagta gtatagacat ataatgagta gtaggaagta attaaatttt
      421 tcctaaacaa aaaaaatagt tgcaaataat ttgattaagt gatatagtaa ataaggtaag
      481 aataaaacaa agaagaagtc cgcttctcac cttacgccgg aggttagtaa ggtaaatata
      541 agttaaagct taattttaat ttaagtttgt ttaaatttgg taacttatat tgcggatgat
      601 tacgtcatcc gctttttatt ttataaaaat tttggaggtg tcctacaatt agcaaagaat
      661 tagcaatcaa tgaacaaata aaagataagg aaataagagt cctttcacca acaggtgaac
      721 aacttggagt aatgcctact aaagaagctc aagcaatggc taatagcaaa aacttagatt
      781 tggttcaaat ctcgccgaat gcaaatccac cagtatgtaa gataatggat tatggaaagt
      841 ttagatatga gcaagcgaga aaagagaaag aagctaagaa aaaacaaaaa actatagttg
      901 taaaagaagt aagacttaga ccaggtattg aacaaaatga tttaaatacg aaagctaata
      961 atgctataaa gttccttaaa aaaggggata aagtcaaagt tgaacttaga tttagaggaa
     1021 gagaattagg acataaagac ataggtaaag aagttatgct taagttttta gatataataa
     1081 aagagtttgg agaaccaaca aaagcccctg catttgaggg taataatatg gttgtaatta
     1141 tagatccaaa aaaatagatg attaactgag aggaggaatt tgtcatgcct aaaatgaaaa
     1201 ctcatagagg tgcagcaaag agattaaaga aaacaggaac tggaaagtta aagagagcta
     1261 aagcttttaa aaaacatata ttaactaaaa aatctgcaaa aactaaaatg aacttaagaa
     1321 aatcaacttt agtaagtgat ggagatgcta agagaatagc acaattatta ccatactaag
     1381 atacagattg taaataataa ctatagaaga gggatataaa aggaggtcat aacgatggca
     1441 agagttaaaa aagctatgaa cgctcgtaaa aagcataaga aaatattaaa acttgcaaaa
     1501 ggattcagag gatctagaag caaattatat agaccagcaa atacattcgt aatgaaagca
     1561 ttaaaaaatg cttatatagg aagaaagtta aagaagagag acttcagaaa actttggata
     1621 caaagaataa atgcagctgc tagaatgaat ggaatatctt attcaagatt aatgaatgga
     1681 ttaaaattat ctggtgttga agttaacaga aaaatgttat ctgaaatggc tatacaagac
     1741 ccagaaggat ttgcaaaatt agcagaagtt gctaaagcaa aattagctta gtattgaatc
     1801 atgagatgta aagtctttga gttatgtaaa taattcaagg acttttttat tttttgaaaa
     1861 atacttatta gtgtcatgta caaccaattt tataatgata aataaaataa gcaatacaat
     1921 agaattttat gagatttatt ataagaattg ttacaattat ttatgatagc tataaaaagt
     1981 catagtaaaa atgatattga tgtatgttga tatatgtata aagctttcaa tcaatcttga
     2041 attaatatta tcaacatgat aatattatct tattaataat ataaataagg gggagataat
     2101 atgaatgaaa aactaatgga ttgttttgta aacccaatta aatgcaagtt attgattgaa
     2161 attttttcaa ataatcgaac tacagctaaa caattaggag aaaagtttca agatatatca
     2221 aaggcaacac tttatcgtta ccttaataaa atgttgaaag atgatattat aaaagtggtt
     2281 gaagaaaata aaataagggg aactgttgaa aaagtatatg ctatgaagtt agatatagct
     2341 gatgatgtga acaaaattat agatgagaac tctggagaag aatatgctca actgtttact
     2401 caatatatga tgggattttt aagagaattt tatgaatacg ctgaaagaaa ggaaaaggat
     2461 atcctaaaag atggttcagg attttctgtc tgtccagtat atgctagtat tgatgagata
     2521 gttgaagtga gtaaaaaaat tgctagtata ctagaacctc taagaaataa ctcacatgaa
     2581 gaaggtagaa gaatgcattc tataggagtg ataattactc cacctaaaga ggatgaaggg
     2641 aaataaatct gatttacatg gggtagagcc aatttataca gagaatcgtt ttatgattta
     2701 catatgtatc cagagcaaag tatctctgct tggattgtac ttcattgtac catttcatcc
     2761 aatgacttgg agtggtacaa tgaagttttt taatttttca tattaatgct aaagaaatga
     2821 actttagacc acatatgcaa ttaggttgca ttatacaatt agaccacata tacaaaataa
     2881 aaatcagtat ttttatagca gataaattga ctgttattct tcttaaaaat catctattag
     2941 ttattgttag catattgaaa gaaattatag taatctattg aataaatgaa tattgcccat
     3001 aatcatataa actgctatag tttaaaataa agcaggacgt taaattttat agtaatctaa
     3061 aaatttaaga gggggatttt atgaaaataa aatttgttat tatgccattg gtgatatttt
     3121 taatggtatt atttgtgggg tgtcaaagta caaaagatac agaagttaaa gcaaaagata
     3181 cagaaattaa aatattaggg acaggtgatt tacattcaat tttgacagac tctatggttt
     3241 catatataaa tgaggaaagg gaaaagaata aaaatctgct tatggtagat gcgggagatt
     3301 tctatggtac acaaagtaga gaaatgtggg aatggtcttc tggaaaaaag ttaattaata
     3361 ttaaaagaaa tggtagagca gagtatgatg acataattaa gagtagtaaa gatgaagtac
     3421 ctatagttaa agatatggca aagttgaaat atgatgctgt agttttggga gataatgaat
     3481 ttatttcaaa tgataagcaa agtcttgata aactggtttc tgattttaaa aataataata
     3541 tgccattggt atcagcaaat atatatgaac aatctggaga aaattatgta caaccatatg
     3601 taatgaaaaa tattaagaca gatgagggca atgtaaaagt tggaatacta ggtcttacta
     3661 taaaagaagt aggggaaacc cttggtcttg aggattttga aaaggataaa aaagctagag
     3721 agcttggaga acaagctgat tacaaaggaa aattatatgc aaatgattta gtagaagatg
     3781 caaagaaatg gataaaagtt atggaaaaag aaagtccaga cataatagtt gcagttgtac
     3841 actcagggga agaacctaaa acagatagaa atccaggaaa tagaataaaa gagttagcaa
     3901 ctacagtgga tggaatagat gcaattgtag ctggtcatac tcatgaaaaa atagatgaac
     3961 acaaatataa aaataaatct ggagatgaag taattgttac acaaccaggt tggcatggag
     4021 atagagtatc agagattaat ttcaaattaa ataaagagaa tggaaagtgg gacataaagg
     4081 aaaagtctag taaattaaaa ataattgata aagaagtaag tatagttgct actgcagatt
     4141 tacattcaca tttctctgat gaattaacag ttgaccttgt taatgaacgt agtaacccaa
     4201 ttgaacctgt tgtagtagat gcaggcgact tcttagaccc tcaaacagat gaaatgactc
     4261 aatggtataa agagtggaaa agtataagag ataataatag tgataaaacg attagtagat
     4321 gcccaatggt catggatatg aatcagggaa tgtatgatgc agtagtactt ggaaatcatg
     4381 aatttgtatc tgaaaaagat gaattttggt cagatgaacg ccttttagat gctgttatag
     4441 aggattttga acaggtggca atttctgtgt tatcggcaaa tatatatagg caatctggta
     4501 aaaattatgt taaaccatat attataaaag atgtggagac gagtgaaggt aatgtaaaag
     4561 taggaatatt gggacttact ataaaagaag taggtaaagg tcttaaaaat gtaaacttac
     4621 aagagcaatt tcaatataag gataaattgt atgcaaatga tttagtggaa gatgcaaaga
     4681 aatgggtaaa agttatgaaa aagaaaaaac cagatataat agttgcagtt gtacattcag
     4741 gagaagaacc aaaaaatcca aaacatccag gaaatagaat aaaagaacta gcaactacag
     4801 tagatggtat tgatgcaatt gttgctagtc atactcatga aaaaatagat gagcatgaat
     4861 ataaaaataa gtctggagaa aaagttatag tgacacaacc aggtgagcat ggtaaatatt
     4921 attctaaaat tacctttaaa gtaaataaag aaaagggttc gtggactatt aatgataaat
     4981 tcagtaaaac aattgaggtt gaataacttt ataaaattta tagataaagt aaattatctg
     5041 atattgacat gatatataag ataaagtttc taatattggt ataatgcata atgtgaaata
     5101 ttttaataat aagagaataa acaagacaaa taaaaatatt ttaacatgta agatatagta
     5161 tgaactatta tactaatgct tactttataa tttgaacatg ttagaataag tcttatttga
     5221 aaattttagt gtattagagt aagtattatt ttactagtaa aaaatattga gaactatatg
     5281 tagatttgct taaaaaggaa tttacatata gttcttttcg tataataaat agtacaatct
     5341 tatatggtaa agataaagtg tgatattaaa ttttattatc atccaaaatc taaggaggag
     5401 tctcttatga aaataaaatt tattatagta gcatcaataa tatttttaat agtattactt
     5461 gtggggtgtc aaagcactaa agatacagaa atcaatgtac tcgccacaag tgatttacat
     5521 tcaattattc cagataattt aatttcctat gtagaagagg agagaaaata tgatgagaat
     5581 ctacttatgg tagatgcagg agattttttt gacatgcaaa gtggtgagat gaataagtgg
     5641 tttactggtc aaaaattagt aagatttaaa gatgggatac cagagtacaa aaaaatagct
     5701 gaaccacgtg aaggagaagt tccattggct aaaaaaatgg caaagctgaa gtatgatgca
     5761 gttacatttg ggaatcatga atttgtatct aatgacaagc agagccttga taaattggtt
     5821 tctgatttta aaaataacaa tataccatta gtatcagcaa acgtatatga acaatctgga
     5881 gaaaactacg taaagccata tgtaatgaaa aatataaata ctgacaaggg aactgtaaag
     5941 gttggtatac ttggtctgac tataaaagaa gtaggggaac gttcaaggtt taaaagtttt
     6001 gaacaagata aaaaggctag agaacttggg gaacaacctc aatacaaagg gaaattatat
     6061 gcaaatgatt tagtagaaga tgcaaataag tgggtaaatg ttatggaaaa aaaagaaaag
     6121 ccagatataa tagttgccat tgtacattca ggtgaagagc caaaaaatcc taaaaatcca
     6181 ggaaatagaa taaaagaact agcaacaact gtagagggaa tagatgctat tgtagcaggt
     6241 catacacatg aaaaaataga acagcataca tataaaaata attctggtga agaagtaata
     6301 gtaacacagc ctggagctca tggtaatagt atatcaaaga ttaattttaa gttggataag
     6361 aagaatgata agtggtttat aaaagacaaa tatagtgaat taaaggtttt tggaaaggaa
     6421 gtaaatataa ttacaacttc tggtctgaat ccaaaatttt cagatgaaat ggcagttaat
     6481 ttgtttaatg aaagagatag agatgttcaa cctatcttta tagatactgg agatttttta
     6541 aatactaata caaaagaaat gactaagtgg gctaaagagt ggcaatacaa tgaaaataaa
     6601 ggcatctata aaaaaataaa tgaatggcca attgtatatc ttggttatga tgctgtagta
     6661 cttggtagcc atgaatttac agaggataaa gagacttttg aggaaaaaaa atctacattg
     6721 gattatatta tagaaaactt tgaagaaatg aagataccag tattatcagc taatatatat
     6781 gatgaatctg gagaaaatta tgtaaaacct tatataattc ataatgtaga aactagggaa
     6841 ggaaatataa aggttggagt attaggtctt actactactg ataaggatga agaagactta
     6901 agtaactcaa gcttaagcaa agactcaaag acttcgaaaa ttcctgaaga aacaggaaag
     6961 ttatatacta ataatctagt aaaagatgca agcgaatggg taaaagttat gcaaaaggaa
     7021 agtcctgatg tgattgttgc agttgtacat tcagataata atagtactct aaaaaatcca
     7081 agtagtgaag tcaaaaaact tgcaatgtca gtagatggaa tagatgctat tgttgtaggt
     7141 catacgaaaa ataaggtaga agaacatatt tacaaaaata agtctgggga tgaggttata
     7201 gtaacacaat ctggagaaga ttgttattta aaaataagtc ttgaactaag aaaagaaaat
     7261 ggcaagtgga atatcataaa caaatatagt aaagcaataa aaatgaagtg aatttattga
     7321 tatataaacc attattaaca ctgattttta taatataata aatactgatt c
//
LOCUS       DAMJXI010000119         7288 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.126, whole genome shotgun sequence.
ACCESSION   DAMJXI010000119 DAMJXI010000000
VERSION     DAMJXI010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7288
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.126"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            148..1473
                     /gene="cdeA"
                     /locus_tag="PC465_003565"
     CDS             148..1473
                     /gene="cdeA"
                     /locus_tag="PC465_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter CdeA"
                     /protein_id="HDF2650833.1"
                     /translation="MENLFTRKFTTFEFLKFVSPAIISMIFISLYTIIDGIFVSTLVG
                     SDALASINIVLPIINLVCGFGIMMATGGGAIVSIRMGENRQDEANSTFSFIVLFSLIV
                     GILFTVISYFFIKEISILLGATDKLLPYCITYGKVMILCTPFYILKFIFEYFARTDGN
                     SKFSLFLSVIGGVTNIILDYVFIKYFGMGLLGAAVATAIGIILTCVLGIIYFLSNKST
                     LKLRKPKTDFRLIRDTMINGSSEMVTELSTGITTFLFNVVALKLAGENGLAALTIVLY
                     AHFLMTSVYLGFAAGVSPLISYNFGAENSDKLKETFKHSLKFIFVSSLLVFIIALVFA
                     PFIVRVFVSPDNTVFKLALQGLKIFAFAFLFVGINIFASGFFTAFHNGKISAIISFSR
                     AFVFIIIGIIILPPMLNMTGLWLTVPFAEVITIFISILFIKKYKCRYKY"
     gene            complement(1568..2362)
                     /locus_tag="PC465_003566"
     CDS             complement(1568..2362)
                     /locus_tag="PC465_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2650834.1"
                     /translation="MNELKPYIKFFNKNTKLYIIIFMIVGIVMNILPVFILKIFGEAS
                     KTNLSTIVNPILTYITILLFVYGVNIANKDFSGALSIRADRKSCIKAIVIDLIILSFV
                     ISILGIVLIFLSKLFIEIITGYSIELSVLLKRDMIWTSISALIDPSTSSMPLTYLNYF
                     VQICINEICIGFIGVLLGAFTYRVRKVTSITILIGLPILMVIYIVNFATKNMHKMLLY
                     LEKIIYSFQNPFILFGTKVGIIVICIIFIILLLRKAPIKEYANDLL"
     gene            complement(2363..3238)
                     /locus_tag="PC465_003567"
     CDS             complement(2363..3238)
                     /locus_tag="PC465_003567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2650835.1"
                     /translation="MSSSIKIENLSHSFKKQNIFNNMSLSFEKNKIYGLLGKNGAGKT
                     TLLNIMVNQLIQNEGEIEILGKNPKEDIKVLEEVCIVREKEFYSPDFKVGQIFEFSSS
                     FYKSYDKGLEKELCKYFDLNTKKKYKQLSRGMKTILSNIIGICSNSAITIFDEPTIGL
                     DAVNRQEFYNIILDSYIKNPRTIIISTHLIDEIDDLLEHVIILNEGKIIIDEEIDVIK
                     QKAHYITGNKEELEKLECIKNIKPKKAFGNAVAYFYYGDFSESDEKILKNSNIDVGYI
                     GLQDMFVNMTKKEEL"
     gene            complement(3242..3610)
                     /locus_tag="PC465_003568"
     CDS             complement(3242..3610)
                     /locus_tag="PC465_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2650836.1"
                     /translation="MKLVLNNEEPIFIQIARAIEDEILSNGIKEEEQVPSTTELSKLY
                     KINPATVLKGINILVDKNILYKKRGIGMFVSDGAKTIIKEARKENFKHNFVKNLLQEA
                     NKLEINREELVDIIINFKED"
     gene            complement(3793..4452)
                     /gene="deoC"
                     /locus_tag="PC465_003569"
     CDS             complement(3793..4452)
                     /gene="deoC"
                     /locus_tag="PC465_003569"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HDF2650837.1"
                     /translation="MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYV
                     KRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDAIENGADEVDMVVNISDIKNKDY
                     DNIGKEIKEIKKAIEDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGG
                     ATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTD
                     Y"
     gene            complement(4488..5675)
                     /gene="murJ"
                     /locus_tag="PC465_003570"
     CDS             complement(4488..5675)
                     /gene="murJ"
                     /locus_tag="PC465_003570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HDF2650838.1"
                     /translation="MKQEPCDFSHGRFRTGIIFIGITSVMSAFLQIKENFIVVGFGSI
                     PYNIVIIISIMLSTIFGPYILPIGAVVAMVVQLLFYMFFVKKTNYKYLYYLNFKDDSL
                     IKLLALLSPVFIGVAVNQVNSLVDTTLASTLVKGSIPALTYADRLNGFVTGTFTASIV
                     SVMYPMLSKLSAENNQKKFTSSVKSSINMIIISMIPISVASIFFATPVVRIIFERGAF
                     DARATQMTATALIFYAVGMTAFGLRDILGKVFYSLQDTKTPMVNGIISVGVNIVLDLV
                     LIKPMAHGGLALATSSSSIACILLLFLNLKRKVGYFGQDKIIKATLKSVVASLIMGVL
                     SYFTYKFIFGILGVGTFNEFVSLAISVIVGGGIYTLLMTIFKVEEVDMILNIAKRKLH
                     LKK"
     gene            complement(5752..6870)
                     /locus_tag="PC465_003571"
     CDS             complement(5752..6870)
                     /locus_tag="PC465_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2650839.1"
                     /translation="MIAVKKAYKFRLYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KNDKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALKDLDNAYKKFFKEKAGFPKF
                     KSKKINRFSYKTNFTNGNIMYCGQHIKLPKLGMVKIRDKQVPQGRILNATISKEPSGR
                     YYVSLCCTDVDIEAFENTNNHIGLDLGIKEFCISSCGEFIENPKYLKKSLNKLAKLQR
                     ELSRKTIGSLNRNKARLKVARLQEHIANQRKDFLQKLSTKLIKENDIICIEDLQVKNM
                     IRKRKLSRLISDVSWSEFIRQLEYKANWHGRQIVKVGKFFASSQICNKCGYKNEEVKN
                     LNIREWICPSCNETHDRDINASRNILKEGLRLITIQNK"
BASE COUNT         2375 a         1156 c          807 g         2950 t
ORIGIN      
        1 agtttattaa ttagcattat actaatttat cttaatatga ttttttgttg attttaagct
       61 gtttatcgta taaataaaat ttttcttgac tatatagtta ctatatagct tattatatat
      121 agagagtaat aaaaggaggt aaaatttatg gaaaatttat ttacaagaaa attcactact
      181 tttgaatttc taaaatttgt ttctcctgca attatatcca tgatatttat atctttgtac
      241 acaataatag atggcatctt tgtatcgaca ttagttggtt ctgatgctct tgctagtata
      301 aatattgtac tacctataat taaccttgtt tgtggatttg gaataatgat ggcaactggt
      361 ggaggtgcta tcgtttctat acgtatgggt gaaaatagac aggatgaagc caactctaca
      421 ttttctttta tagttttgtt ttcattgatt gttgggattt tattcacagt aatctcatat
      481 ttctttatca aagaaatatc tattttgctt ggtgcaacag ataagttatt accatattgt
      541 ataacttatg gtaaagttat gattttatgt acaccatttt atattttaaa atttatattt
      601 gagtactttg caagaactga tggaaattct aaatttagtt tatttctatc agtcattggt
      661 ggtgtaacaa atataatatt ggattatgta tttattaaat attttggaat gggtctttta
      721 ggagctgcag ttgcaactgc tataggtatt attttaactt gtgttttagg tattatttac
      781 ttcttatcta ataaatctac actaaaatta agaaaaccaa aaaccgattt tagacttata
      841 agagatacta tgataaacgg ttcttctgaa atggttacag aattatctac aggaattaca
      901 acattcttat ttaatgtagt agctttaaaa ttagcaggag aaaatggact tgctgctctt
      961 actatagtat tgtatgctca ttttttaatg acatcagtct atctaggatt cgctgctgga
     1021 gtgtctccat taataagcta taattttggt gctgaaaaca gtgataaatt aaaagaaaca
     1081 tttaaacatt ctctaaaatt tatatttgtt tcttctcttt tagtgtttat tattgcttta
     1141 gtatttgcac catttattgt tagggtcttt gtaagtccag ataacacagt atttaaacta
     1201 gccttacaag gattaaaaat atttgcattt gcttttttgt ttgttggtat aaatatattt
     1261 gcatcaggat tttttacagc atttcacaat ggaaaaattt cagctattat atcttttagt
     1321 cgtgcctttg tttttataat cataggaatc ataattcttc ctcctatgtt aaacatgact
     1381 ggattatggc ttacagttcc atttgctgag gttataacca tatttatatc tattctattt
     1441 ataaaaaaat ataaatgtag atataagtat taaaaattaa tacttaaaat caacatttat
     1501 taaaactaat aaacctgctt taaaatacaa atttacaaat ttgattttta agcaggtttt
     1561 attttagtta taataagtca tttgcatact ctttaattgg tgcttttcta agtaataaaa
     1621 ttataaatat tatgcaaata actataattc ctacctttgt tccaaataaa ataaaaggat
     1681 tctgaaatga ataaataatt ttttctaaat acagtagcat tttatgcata tttttagttg
     1741 caaaattaac tatataaatt accattaata tcggtaatcc tatcaatata gtaatactag
     1801 taacttttct aactctatat gtaaaagctc caagtaacac tcctataaaa cctatacata
     1861 tttcatttat acatatttgt acaaaataat ttaaataagt tagtggcata cttgatgttg
     1921 aaggatctat cagtgctgat atagatgtcc aaatcatatc tctctttagt aaaactgata
     1981 gttctatact gtaacctgtt ataatttcta taaataactt cgataaaaaa atcaaaacta
     2041 tacctaaaat agaaatcaca aagcttaaaa taattaaatc tatgacaata gcttttatac
     2101 aactttttct atctgctctt atacttaaag ctcctgaaaa gtctttattt gctatattta
     2161 ctccatacac aaatagcagt atagttatat atgttaaaat aggattcaca atcgtggata
     2221 aattagtttt agatgcttct ccaaaaatct tgagaataaa cactggcaaa atattcataa
     2281 caattcccac aatcataaat ataattatat acaatttagt atttttatta aaaaatttta
     2341 tatatggctt taattcattc aattacaatt cctccttctt agtcatgtta acaaacatat
     2401 cttgtagccc tatgtatcct acatcaatat ttgaattttt aagtattttt tcatcacttt
     2461 cactaaaatc accatagtaa aaataagcaa ctgcatttcc aaatgccttt ttaggtttta
     2521 tattttttat acattctaat ttttctaact cttctttatt tccagtaata taatgagctt
     2581 tttgttttat gacatcaatt tcttcatcta taataatttt tccctcattt aatattatta
     2641 catgctccag taaatcatct atttcatcaa tcaaatgagt tgatattatt attgtccttg
     2701 gattttttat ataactatct aaaattatgt tataaaactc ttgtctattt actgcatcca
     2761 aaccaattgt tggctcatca aatatggtga tagctgaatt agaacaaata cctattatat
     2821 ttgaaagtat agttttcata cctcttgaca gttgtttata ctttttttta gtatttaaat
     2881 caaaatattt gcataattct ttttctaagc ctttatcata acttttataa aaactagaag
     2941 aaaattcaaa tatctgacct actttaaaat ctggactata aaattctttt tccctgacaa
     3001 tacaaacttc ttccaaaact tttatatctt cttttgggtt ctttcctaat atttctatct
     3061 caccttcatt ttgaattaac tgatttacca ttatatttaa taatgttgtt tttccagctc
     3121 cattcttacc taataaacca tatatcttat ttttttcaaa gcttagagac atattattaa
     3181 aaatattttg cttcttaaaa ctgtgagata aattttctat cttaatagaa ctactcatat
     3241 attaatcctc cttgaaatta attataatat caaccaattc ttctctattt atttctaatt
     3301 tgttagcttc ttgaagtagg ttttttacaa aattatgttt aaaattttct tttctagctt
     3361 cttttataat agtttttgca ccatctgata caaacatccc tatccccctc ttcttatata
     3421 aaatattttt atcaaccaat atatttatac cttttaatac tgtagctgga ttaattttat
     3481 aaagctttga aagctctgtt gttgatggaa cctgttcttc ttcttttatt ccatttgata
     3541 gtatctcatc ttcaattgct cgtgctatct gaataaatat aggttcttca ttatttaata
     3601 ctaatttcat aggttcctcc tttctccatc agttagttac tcaactaatt aactatataa
     3661 cttataatat cttgaaaaat attttctgtc aatactaaat aaaaaacaga gggaaaattc
     3721 cctctgtttt ttgttcttta tatttataat taaattttaa tttttgtaat cctatcccat
     3781 aagttaaaaa ctttaataat ctgttgtatc ttcatttttt aatattttac atattgagct
     3841 agttcctaac ctttctgctc ctgcctctat aaatttttct gcatcagaaa ttgatttaac
     3901 tccccctgca gcttttattt ttacattttt tccaacatgc tctttcataa gctttatatc
     3961 ttctaaagta gctccacctg ttcccattcc agtagatgtt tttataaaat ctgaacctga
     4021 cattgttact atttcacaca tttttatttt ttcatcttca tctaaataac atgtctctat
     4081 aatgactttt aatactttat cttctatagc tttttttatt tcttttattt cttttcctat
     4141 attatcataa tctttatttt ttatatctga aatgtttaca accatatcaa cttcatctgc
     4201 tccattttca atagcatctt ttgcttcaaa tacttttgta gcagtagttt gatatcccaa
     4261 agggaaccct atcactgtac atatctttat tttacctttt agatattctg atgctctttt
     4321 cacatatgat ggtggtatgc aaactgatgc tacactcata tctacagctt catcacataa
     4381 aattttaata tcttcccatg tagttgtagc ttttaaaata gtatggtcta ctgtttttaa
     4441 tatatgtttc ataaaatcct cctaaattta taattaatat aattagatta cttttttaaa
     4501 tgcaattttc tctttgcaat attcagtatc atatcaacct cttcaacttt aaaaatagtc
     4561 attagtagtg tataaattcc acctccaact ataactgaaa tagctagtga tacaaactca
     4621 ttaaatgttc ctactcccaa aattccaaat ataaatttat acgtaaagta tgataaaaca
     4681 cccataatta aagatgcaac taccgatttc aaagttgctt ttattatttt atcttgtcca
     4741 aaatatccaa cttttctctt taggttcaag aagagtaaca atatacatgc aattgatgat
     4801 gaactagttg caagagcaag accaccatga gccattggtt ttattaaaac taagtccaat
     4861 actatattta cccctacaga tataatccca tttaccatag gtgtttttgt gtcttgtaat
     4921 gaataaaaaa cctttcccaa aatatctctt aagccaaatg cagtcatacc aactgcataa
     4981 aaaattaagg cagttgctgt catttgggtt gccctcgcat caaaagcacc tctctcaaaa
     5041 atgattctaa caacaggagt tgcaaaaaaa atagaagcaa ctgaaatagg aatcatagaa
     5101 attattatca tatttatact agatttaact gaactagtaa acttcttttg attattttct
     5161 gcacttaact tagataacat aggatacata acagatacta ttgaagctgt aaatgtccct
     5221 gtaacaaaac catttaatct atctgcataa gtaagtgctg gaatgcttcc tttaactaat
     5281 gttgaggcta aagttgtatc taccaatgag ttcacttgat taacagcaac acctataaat
     5341 actggtgaaa gtaatgctag taatttaata aggctatcat ctttaaagtt taagtagtat
     5401 aagtatttgt agttcgtttt tttaacaaaa aacatgtaaa agagcagttg aactaccata
     5461 gcaaccacag caccaattgg aagtatgtat ggtccaaata tggtacttaa cattattgaa
     5521 ataattatta ctatattata gggtatactt ccaaatccaa ctacaataaa gttctcttta
     5581 atttgtaaaa atgctgacat aacacttgta atacctatga atattattcc tgttctgaac
     5641 ctcccatgac taaagtcaca gggttcctgc ttcatagaat tttgcatact aaaatatgtc
     5701 ttactaattc tccacaggct atccccgtag ttcctacggt tcttacatac gttatttatt
     5761 ttgaattgtt attagtctta atccttcttt taatatattt ctacttgcat ttatatctct
     5821 atcgtgagtt tcattacaac taggacaaat ccattctctt atatttaagt tcttaacttc
     5881 ctcgttttta tacccacatt tattgcatat ttgtgaactt gcaaagaatt tacctacctt
     5941 tacaatttgt ctaccatgcc aattagcctt gtattctaat tgacgaataa actctgacca
     6001 tgatacatca gaaattaagc gagatagttt acgtttccta atcatattct ttacttgtaa
     6061 atcttctatg caaataatat cgttctcttt tattaattta gtagatagtt tttgtagaaa
     6121 atcctttctt tgattggcta tatgttcttg aagtcttgca acttttaatc ttgctttatt
     6181 tctatttaaa ctaccgattg tttttctcga taattctctt tgtaatttag caagtttgtt
     6241 taatgacttc ttaagatact taggattttc tataaattct ccacaacttg agatacaaaa
     6301 ttctttaatt cccaaatcta aacctatatg attattagta ttttcaaatg cttcaatatc
     6361 tacatcagta cagcataatg atacataata tctaccactt ggttctttag atatagtagc
     6421 attaagtatt ctaccttgag gtacttgttt atcccttatc ttaaccatac caagtttagg
     6481 tagttttata tgttgaccac aatacataat gtttccattt gtaaagttag ttttatatga
     6541 aaatctatta attttctttg atttaaattt aggaaatcct gctttttctt taaagaattt
     6601 tttatatgca ttatctaaat cttttaaggc gttttgtagt gaaaatttgt caggttcttt
     6661 aagccacttt aattcttttt ttaaattggt caaatcagaa ctacactgtt tataagtaaa
     6721 agtttcttta tcgtttttat aaacatctat tcttttagca agatacttat tatatacaaa
     6781 tctacaacat ccaaaagttt tgttaattaa ctcttgttgc tttttatttg gatacagtct
     6841 aaacttataa gcttttttca ctgctatcac ctcactttaa ttgttttttg atacactttt
     6901 taatgatttt atcacatttt atcacattta atatattata taatgctgtg gtaaacaatt
     6961 tattaatcac ctataataat gttaacaaat gtaattattt aaaacaatta tttagaaggt
     7021 tttatattta attttaaata acatatttaa gaaccgtaag tcttaacttt tatcattttt
     7081 gaggttgtcg ttcacataag ttcgctacta cctatgcagt tctcttatga acttcttaca
     7141 ctttcatgta agcacagact atatcttatc cttcagcatt atccgttaag gtctacccac
     7201 ttccactacc aatagcttgt agtgtacttc cctcaagagg aatagtcgtt gaagtttctc
     7261 ctattcggag tttacctgct gattgccc
//
LOCUS       DAMJXI010000120         7213 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.127, whole genome shotgun sequence.
ACCESSION   DAMJXI010000120 DAMJXI010000000
VERSION     DAMJXI010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7213
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.127"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            242..1069
                     /locus_tag="PC465_003572"
     CDS             242..1069
                     /locus_tag="PC465_003572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HDF2650840.1"
                     /translation="MDLSKKVKILENASDGKSEFEILEFEKLEGASSPLMAMGLYFAR
                     EAGLKARQIKIKLNNSSIKTEAGALYYYKGNISSETKIGGVGGLFKKGISGALTNESM
                     MKPVYKGTGEVYLEPSFRHYLFMSLDNDSIIVDKGLFYCCSDTIEVKAFTQKNFSSAL
                     LGGEGFFQIELSGTGVIVLECVVPQSEIVEYELKNGEELKVDGNFAIARTSGVNFSVT
                     KSDKSLIGSALNGEGFLNTFTGNGTVWLAPTQVMYEKLSFGAMPTNDNMNNKVSKQK"
     gene            2091..2555
                     /locus_tag="PC465_003573"
     CDS             2091..2555
                     /locus_tag="PC465_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2650841.1"
                     /translation="MNLNKVKFTEEHAIEVTNWKYEGKYSIYNLPPWEEIKKKNFSLA
                     KEDKRKNFISFINDNKELIGFISLLDEGSSVFFGIGMKPNYCGMGIGKEIIGLGLQEC
                     RNKYSTKPIVLNVRTWNMRALKCYESQGFKIVETKVQKTHLGDGEFFVMRYQ"
     gene            complement(2822..3466)
                     /locus_tag="PC465_003574"
     CDS             complement(2822..3466)
                     /locus_tag="PC465_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2650842.1"
                     /translation="MFGQSFQNCLVLIKENFKLSTLTNLICSIILLCMIPLIQGVANL
                     DRISTAICLENYVAIIGGVMLVPVFSLEQSKEIDEIVSSKALSQVIVQLIRILMSIIG
                     IVVLIIGFVNVLIYLGCNFPVVEYIIGSFASAMFIGSLGMFFSNLFNNTIIGYMISIG
                     YLILNMMTKGKYVGKFFIMSMSQGSFDEKYWLILGSVVLIIASLLIKPVKRKIR"
     gene            complement(3396..4685)
                     /locus_tag="PC465_003575"
     CDS             complement(3396..4685)
                     /locus_tag="PC465_003575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2650843.1"
                     /translation="MNLFIKECKNILKSMIYYIFIVVLVFFYISQLGSSVSNDVSKNI
                     PNDGNPLVAPQKVENIEEYYSVHNQYPYGQKESMKTEKVIPNATINLIREYQKNTYTT
                     YPTGVVKYIKLDQNKTKTIEKYIEEITGKSISEINSLWKTDESIKIDYSKVSLERFEE
                     IMQRVDDILGGGSAYAFDKLQRFGVVPVTYDEAMKNYNYTIQKDKVSNGYARIFCDYI
                     GIVLSIFPVFVAVFMSLKDKRSRMREIIYSKQVSSCKIVLSRYFALVFMMILPVLILG
                     MKDLLPLIFFAKDKGISIDNLAFIKYTLWWILPTLMIVTAVGMSITILTDTPVAIIVQ
                     LIWWFYSINSTGLKGDYSTMGLMIRHNSVLNGDIIIQNFNQIIINRIVISLGALVLVL
                     LAIFLYEQKRRGNLDVWAKFSKLFSSNKRKLQIKHFN"
     gene            complement(4682..5554)
                     /locus_tag="PC465_003576"
     CDS             complement(4682..5554)
                     /locus_tag="PC465_003576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2650844.1"
                     /translation="MEMKIAVSNLSKRFGKKQALDNINLEIDSGMFGLLGRNGAGKTT
                     FMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFSMYPNMTVYKAMDYLAVL
                     SDIPLRKRRKIIAKLLSKVNLTNYQNVKVKSLSGGMNRRLGIAQSLIHNPRVLIVDEP
                     TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILNSGKVIYNGSTEA
                     LAKLAEEKVYSIEVDKKDIENIKSRFIVIGMLTHGGKAILRIISDDKPFETAVNCNPT
                     IEDGYMLIMGGDNI"
     gene            complement(6083..6574)
                     /locus_tag="PC465_003577"
     CDS             complement(6083..6574)
                     /locus_tag="PC465_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HDF2650845.1"
                     /translation="MGMIGCYTKISEENVFKLQQSEENLQDFVFEDANENSTINIDKA
                     WHAIHFTLTGCPFGGDDDNIFSKLVLSGNILMEIDGEFPVMLITANDVKKLSKAMNSL
                     EEQAFRKRFNINEMLENNIYPVMNDESEDDFFEYVWANLIELKKFIQEASNDGLAVIF
                     FIM"
BASE COUNT         2644 a          969 c          840 g         2760 t
ORIGIN      
        1 aaataatttt aacatgccca taaaatataa tacccacgaa tgataaataa tactcaaaat
       61 gtctattgaa ataactatac atccttaaat aacttaactt aaatctaaac atttcaaaaa
      121 cttcttaaaa atatgtaaaa atttgatgat aaagtagcga ttttttcaaa aaaaatgtaa
      181 tatagagtta tatcttataa tattttagag ataaatttta tcatagtggg gagaaatttg
      241 tatggattta agcaaaaaag taaaaatttt agaaaatgca tcagatggca aaagcgaatt
      301 tgagatatta gaatttgaaa aacttgaggg agcttctagc ccattaatgg caatgggatt
      361 atattttgct agagaagctg gtttgaaagc tagacaaatt aagataaaat taaataattc
      421 atcaataaaa acagaagctg gtgcattata ctattataaa ggaaatatat cttctgaaac
      481 taagattggt ggtgttggag gtctttttaa aaaaggaata tcaggagcac ttactaatga
      541 atcaatgatg aaacctgtat acaaaggtac tggagaagtt tatttggaac cttcttttag
      601 acattattta tttatgagtc ttgataatga ttctataatt gttgataaag gattattcta
      661 ttgttgctct gatacaatag aagtaaaagc atttacacaa aagaacttct catctgcttt
      721 acttggtggt gaaggcttct tccaaataga attaagtggt actggtgtaa tcgttctgga
      781 atgtgttgta cctcaaagtg aaattgtaga gtatgaattg aaaaatggtg aagaattaaa
      841 ggtagatggt aactttgcaa tagcaagaac atctggtgtt aatttttctg ttacaaaatc
      901 agataaatct ttaattggtt ctgctttaaa tggtgaaggt ttcttaaata catttactgg
      961 taatggtaca gtttggctag ctccaactca agtaatgtat gaaaaactaa gttttggagc
     1021 aatgcctact aatgataata tgaataataa agtttctaag caaaaatagt tgttttataa
     1081 atatttatta aatcattatt gattttataa agtcactata aattttatta gattattatt
     1141 ataaaatcag agtgtggaaa tgtttatgtg tattctttaa ataaaaattt ccacattctg
     1201 taaggttatt atacttgata tataaaattc aatttaggaa catagtctaa catttataaa
     1261 catattaagg taatgatttc tcttggtaat tattctcata tcttattctt tgattatatt
     1321 tatcttattc ctagccctta tgtcatatta tatttcttat cttattactt ataattagca
     1381 ttaacttatc taaaatcttg tattttttta atagtaaagt ttacatctat attaaaaagt
     1441 ttacatctat attaatttca taaaacaatc aaggtagtca agagattcaa ctttatttga
     1501 ttttaaaaat ttaagtgaat ttgttcttat acacaccttt ttaaaattat atctgtagaa
     1561 aatatcattt agagctataa ttaaattaac ttattaaatt ttagaaaatt tattaaaaaa
     1621 tataagttaa attaatattt ttaaagattc tttttgtaac tactagaata ctaatttagt
     1681 agttattgta tctctaaagt ttaagcatgg atagatatac atttgataat ttgcctataa
     1741 tttacctact acttggagta ttggagcaaa tacaatatat taataataag ttcctaaagc
     1801 caataaatta actaatacac ataaagatat tgatgttgat tatacaacta taagaaacgg
     1861 atttaacaga atttaatcaa gctaagaaat tatatatatc gtgatgtttt tgaattagaa
     1921 ggtaattcaa aattagttta tagtcttctg tgaatccaat aaaaagtaca gggtacaaga
     1981 attgttagta aaatttttaa agattttatg gataaatata aatagtttta cttattttct
     2041 aaaactttaa aataccatta attaccttaa atattttaat aggaggacat atgaatttaa
     2101 ataaagttaa atttactgaa gaacatgcta ttgaagttac taattggaaa tatgaaggta
     2161 aatattcaat atacaatcta cctccatggg aggaaattaa aaagaagaat ttttcactag
     2221 caaaagaaga taaaagaaaa aattttataa gttttataaa tgacaataaa gaattgatag
     2281 gttttataag cttattagat gaaggaagct ctgtattctt tggtattggt atgaaaccga
     2341 attattgcgg aatgggaatt ggtaaagaaa taattggcct aggattacaa gaatgtagaa
     2401 ataaatatag tactaaacca attgtattaa atgtaagaac ctggaacatg agagctttaa
     2461 aatgttatga gtctcaagga tttaaaatag ttgagactaa ggtacagaaa acgcatttag
     2521 gagatggaga attttttgtt atgaggtatc aatagtttat aacaatagtc ttattgttaa
     2581 tacaacaatt aaaataaaaa aatacatatg tgtaggtcat agcaataagt gtctttgaaa
     2641 tataaatttg agagcttttg ataaaatttg gtatacatat atattttata ctacggatat
     2701 ataaatctat ctacatacat aaagagattg taagtaggtt tgtgtatata aaaatagatt
     2761 tatatttcat aaatgtacct tttatttgta ttacctttat tttatctaag ctctcatttt
     2821 attatctaat cttccttttt actggtttta ttaagagaga tgcaattatc aacacaacac
     2881 ttccaagtat cagccaatat ttctcatcaa aactaccttg actcatagac attataaaaa
     2941 attttccaac atacttgcct ttagtcatca tatttaaaat taaatatcct atagatatca
     3001 tataacctat gattgtatta ttaaataaat ttgagaaaaa cattcctaaa cttcctataa
     3061 acatagctga tgcgaaactt ccaataatat actcaactac tggaaaatta catccaagat
     3121 atattaaaac atttacaaaa cctatgatta ataccactat acctataatt gacatcagta
     3181 tcctaattaa ttgtacaata acttgagata atgcttttga agatactatc tcatcaattt
     3241 cttttgattg ctctagcgaa aatacaggta ccaacattac tccccctatt attgcaacat
     3301 aattttctaa acatatagct gttgaaattc tgtctaaatt agctactcct tgtattagag
     3361 gaatcataca tagcaatata attgaacata ttaaattagt taaagtgctt aatttgaagt
     3421 tttcttttat tagaactaaa cagttttgaa aactttgccc aaacatcaag attccccctt
     3481 cttttttgct catataagaa tatagctaac aaaacaagca ccaatgctcc caagcttatc
     3541 acaattctat taattataat ttgattgaag ttttgtataa taatatctcc atttaataca
     3601 ctattatgtc ttatcattag ccccattgtt gaataatcac ctttgagtcc tgtagaattt
     3661 atactgtaaa accaccaaat taattgcaca ataattgcta ctggtgtatc tgttaatata
     3721 gtaatactca ttcctacagc ggtaactatc ataagagttg gtagtatcca ccataatgta
     3781 tattttataa atgctaagtt atcaatagat atacctttat ctttagcaaa gaaaatcaaa
     3841 ggaagtaaat ctttcatacc taaaattaat acaggcaata tcatcataaa gacaagtgca
     3901 aaatatcttg ataaaactat tttgcatgaa gatacttgtt ttgaataaat aatctctctc
     3961 attcttgaac gcttatcttt aagtgacata aaaactgcca caaatactgg aaatatactt
     4021 aaaactatac ctatataatc gcaaaaaatt cttgcatacc cattactaac tttatctttt
     4081 tgtattgtat agttgtaatt cttcatagct tcatcatagg taactggaac tactccaaat
     4141 ctttgtaact tgtcaaaagc atatgcagac cctcctccta aaatgtcgtc tactctttgc
     4201 attatttctt caaatctttc aagagatact ttagaataat ctatttttat actttcatca
     4261 gttttccaaa gtgaatttat ttcgctaata cttttaccag ttatttcttc tatatatttt
     4321 tctatggtct tcgttttatt ttggtctaat tttatatact taactacccc tgttggatac
     4381 gttgtatatg tgtttttttg atattctcta attaggttta tagttgcatt tggaatgacc
     4441 ttttctgttt tcatagattc tttttgacca tatggatatt gattgtgtac agaataatat
     4501 tcctcaatat tctctacttt ttgtggagca actaatggat ttccatcatt aggaatattt
     4561 ttacttacat catttgaaac tgaacttcca agttgagaaa tatagaaaaa aactaaaact
     4621 acaataaaaa tataatatat catactcttt aatatatttt tacattcttt tataaataga
     4681 ttcatatatt atctcctccc attataagca tatagccatc ttcaatagtt ggattacaat
     4741 ttactgctgt ctcaaaaggt ttatcatctg atataatcct aagtatagcc tttccaccat
     4801 gagtcaacat tcctataact ataaatctac tttttatatt ttcaatatct tttttatcta
     4861 cttcaatact atatactttc tcttcagcta gttttgctaa tgcttctgtt gagccattgt
     4921 atatgacttt tccactattc aatatagcta cgttttcaca tgtagcttct atatctccaa
     4981 caatatgtgt agataaaata acgattctat catttgcaat ttcgcatagt aaatttctaa
     5041 atcttatacg ttcttctggg tcaagacctg ctgtcggctc atctactatt aaaactctgg
     5101 gattatgaat taatgattgt gctatcccaa gccttctatt catacctcca gataaagatt
     5161 ttactttcac attttgataa ttagtaaggt ttactttgct taataacttt gctataattt
     5221 ttcttctttt tcttagtggt atatccgata aaactgctaa ataatccatt gctttatata
     5281 ctgtcatgtt aggatacatt gaaaagtctt gtggcaaata accaaccata tttctaattt
     5341 ccttagtatt ctcaatagga actccacaca tatgtattga accttctgtt tttgataata
     5401 aagtggctaa aattctcata aatgtggttt ttcctgctcc atttcttcct aaaagaccaa
     5461 acataccact gtcgatttca agatttatat tatcaagtgc ttgttttttc ccaaatcttt
     5521 tgctaagatt ggatactgct attttcattt ccatatataa atacaccccc agaaacaatt
     5581 ttatagaatt ttatttttat aaatttttac tgtattttca taataaattc taaaacttaa
     5641 gatattattt ataaatttct aaattttttc taaagatttt aatttttctg tttttaatta
     5701 aattaaagta tctttgtttc tgaaattttt taagtttatg aagttataat ttaatatata
     5761 tttattttat ttgtgagtct atttttatat ataatgaaaa atgtgataag tatccaaaag
     5821 aattactgga tataataaga tagggtattt agccttttaa gataaataaa aatatctgca
     5881 actatatatt gcaaaaattt aaaactaatt tatatatgct aatataaata tttataaaga
     5941 cataagacaa atttacctac agatttaaat ttaacttata tattttaaaa ggctaatata
     6001 atatgtattt tcttctatac aatcaaaagg cttcatatct aagatatgtg atgacactaa
     6061 tattcacaat ttttagtaat tatcacatta taaaaaatat tacagctagt ccatcattag
     6121 atgcttcttg tataaacttt ttaagctcaa ttagatttgc ccatacatat tcaaaaaaat
     6181 catcttcact ctcatcattc ataacaggat aaatattatt ttctaacatc tcattaatat
     6241 taaatctttt tctaaatgct tgttcttcca aactgttcat tgcttttgat agttttttta
     6301 catcatttgc tgtaatcaac atgacaggaa attctccatc aatttccata agtatgtttc
     6361 cacttagtac taatttgcta aatatattat catcatctcc accaaaagga caacctgtca
     6421 aagtaaagtg aatggcatgc catgctttat caatattgat agtactattt tcgttggcat
     6481 cttcaaaaac aaaatcttgt aaattttctt ctgattgctg taatttaaaa acattctctt
     6541 cacttatttt agtataacat cctatcatcc ccataattac attcctccta agtagcgttt
     6601 ttttaattgt aacttataat taaacttagt tacaataaaa tatattgaga aaagtattat
     6661 ttcatcttaa atttaaatac ctatattatc aactaaaatt ctgtgtttat agcgtaagta
     6721 ttattatttt ttcctaaaaa ttaaatgaat cagaagttct ataggcaata ttgactataa
     6781 ataaggacta ttacttttaa aaaaaattta agaaattata ctgtagaatc atgctctact
     6841 tattagcttc aaataaaaaa taaatcatgt tctcaaatta aataataaat aacaataaat
     6901 ttaaatttta aactataaga gtttctgaag tgttaataag cataccaata attatatgtg
     6961 taagaatttg atttaataga tataaataat ttttacatta attataaata tattaaccta
     7021 ttgttataaa ttctaaaaaa gaaaagttat cttaaataaa aaataagtgt atcttaaatt
     7081 ttaaatgata cacttatttt tatattgaaa ttatattttt taatatctat tcttaattag
     7141 gtatttttaa attatctgtt tacattaaat atttcttaat tacttatctt tcagctagct
     7201 ttttctatta aat
//
LOCUS       DAMJXI010000121         7110 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.128, whole genome shotgun sequence.
ACCESSION   DAMJXI010000121 DAMJXI010000000
VERSION     DAMJXI010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7110
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.128"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            24..1094
                     /locus_tag="PC465_003578"
     CDS             24..1094
                     /locus_tag="PC465_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2650846.1"
                     /translation="MPLLADFFNVSIDKLLNYKIDLSEEEVMKIYKELESGFARIEID
                     LSTEEPKEEFRQDLESVKKLSNMYIEKYPKSYLLKLRICSLYQMYSYKFGKSELNDRV
                     KETTNILEDIVRNTDDIQIKETALIILSNAYCMLEDYEKAELYLNMIHKSIGDTSVNL
                     AMIYLKQNRLEEAEILLQNKLFSNVFNISMDCKGIINVYKNQYKELKKKLENRNFNKN
                     AIEREMEYIKNKLLGYANLSLEIKKMLSEDKGAFFSMYMDYMELSLIFLFFNMKEEAK
                     KALYSLKEILEKYPIHENLDVSQMRFFDKVESKNLYTFNIYTNLLIVLNDDSYNELRE
                     EPIFKDVIEKILDMEKMLKNKE"
     gene            complement(1513..2034)
                     /locus_tag="PC465_003579"
     CDS             complement(1513..2034)
                     /locus_tag="PC465_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2650847.1"
                     /translation="MKFERLRTSENKLYYKAMELYKISFPFHEQRKSSLQEEILKNKE
                     YQFNLIYNKNQFVGIILCWETDDFIYVEHFCIFPEMRNNRYGQRALELLNKKGKTIIL
                     EIDLPIDEISIYRKAFYERVKYKTNNYEHIHPPYHEKFNGHNLIVMSYPEKLSKMEYD
                     KFNHYLRNNVMSF"
     gene            2390..3187
                     /locus_tag="PC465_003580"
     CDS             2390..3187
                     /locus_tag="PC465_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HDF2650848.1"
                     /translation="MEKREKRIIISSLLSVSILMGLVSIYSILNKEDIILTVKGQEQK
                     VSSFKKTVEELLDEQGVKYNSEDKINPSLDTELKDDMKIKVVKVTKSKKEEIEKIPFD
                     TKHVNDSNLLKGKSKVYQEGQEGEKKLVYNLTYHDGKLVKKVLSKEVISKEPTTKIIK
                     YGTKEKVLIASRGANIRGGKHMKVVATAYAGDTITSTGTTPRWGVIAVDPRVIPYGTK
                     VYIPKLGMTFVAEDCGGAIKGNRIDIFMNSEGKASNWGRKSIDIYLH"
     gene            3297..3887
                     /locus_tag="PC465_003581"
     CDS             3297..3887
                     /locus_tag="PC465_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HDF2650849.1"
                     /translation="MKIVCLGDSLTYGFGVSRSNSWTNIVNKETRLEIVNKGINGDTT
                     SGMLARFNEDVVKNSPDIVFIMGGTNDFIAGAGNKIINSNIMAMVHQSYSKNIIPIIG
                     IPLKPDIPNVREDWSCFTDFNIVSQNLESYSYWIKKFCMTFNTNFVDFYSEYNKNMEL
                     EGYKKLYFDGLHPTKEGHRIMAYIFINSINKYIEEL"
     gene            3953..5650
                     /locus_tag="PC465_003582"
     CDS             3953..5650
                     /locus_tag="PC465_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HDF2650850.1"
                     /translation="MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEF
                     GTAGLRGIIEAGTNRINKYTVRRATFGLANYILENTTKEETSRGVVIAHDNRHKSRQF
                     CIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
                     EDGAQVMPEIANAITEKVNSIHDYSTIPTLTEANKNLVVLLDESQDTKFIEAVKSQII
                     RKDLVKNVGKSFKIVYTPLCGTGNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYP
                     NPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEYALLTGNQIGGMLTH
                     YIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQ
                     NKNRSYVFGYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGMSLYDGLIELYKK
                     YGFFKEQTISLTLKGIEGVEKIKEIISYFRENQIDYINSIKVVDKKDYKNGIDNLPKS
                     DVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDMVEKLK"
     gene            5864..6703
                     /locus_tag="PC465_003583"
     CDS             5864..6703
                     /locus_tag="PC465_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HDF2650851.1"
                     /translation="MFGIDKKLIEYIIAKSNYSELSSKSAEVSFFLMLSIFPFLIFTI
                     SSIAYIPILHLNKYIALFRNMMPEGAFAVLSSIIVSAIDNRNLKFLAVSFVLTMWTFS
                     RAVKALIKGMNRAYKVKETRSFFKILSISFLFTIMLLVLIFLSMIFLVYGEKIGYFIF
                     NLVGLDEIFIKIWDILRYTVGIITIIVIFTLLYKYTPNKKLTIKESAPGAIFATFAWF
                     LVSFLYSYYTNYYANYEVIYGSIAEIIVLMTWMYFSSWSIVIGYEVNSRLYFRKIRHE
                     MLK"
BASE COUNT         2842 a          694 c         1161 g         2413 t
ORIGIN      
        1 attcttaccc agatatagaa ttattgcctt tattagcaga cttttttaat gtgtctattg
       61 ataagctttt aaattacaag attgatttaa gtgaagaaga agtaatgaaa atttataaag
      121 aattagaatc aggctttgct agaattgaaa ttgatttatc aacagaagaa ccaaaagaag
      181 aatttagaca agacttagaa tctgtaaaaa agctttccaa tatgtatata gagaagtatc
      241 ctaaaagcta tttattgaag ctaaggatat gttcgctgta tcagatgtat tcatataaat
      301 ttggtaagag tgaacttaat gacagagtaa aagaaacaac gaatattctt gaagatatag
      361 tgagaaatac agatgatatc caaataaaag aaacagctct tattatatta tcaaacgcat
      421 attgtatgtt ggaggattat gaaaaggcag agttgtattt aaatatgata cataagtcaa
      481 taggggatac aagtgttaat ttagctatga tatatttaaa gcaaaataga cttgaagaag
      541 cagaaatatt gcttcaaaat aaattgttta gtaatgtatt taatataagc atggattgta
      601 agggaataat taatgtatac aaaaatcaat acaaggaatt aaagaaaaaa ttggagaata
      661 gaaattttaa taaaaatgca attgagagag aaatggagta tataaaaaat aagttgctgg
      721 ggtatgcaaa tctttcttta gaaataaaaa aaatgctcag tgaagataaa ggtgcatttt
      781 ttagtatgta tatggattat atggaattat ctctaatttt tttatttttt aacatgaaag
      841 aagaagcaaa aaaagcctta tatagtctaa aagaaatatt agaaaaatat cctatacatg
      901 aaaatttgga tgtaagtcaa atgagatttt ttgataaggt agagtctaaa aatttatata
      961 cttttaatat atatacaaac ttgttaattg tacttaatga tgatagttat aatgagctta
     1021 gagaagaacc aatttttaag gatgtaattg aaaagatttt agatatggaa aaaatgttga
     1081 aaaataaaga ataagtaaaa atttaatata ggacttaaag attaatcaaa ttaaaagaaa
     1141 gtgtttcaaa ataaaaattt gaatcacctt ttttgtctgt cttaaacagt tatttagaaa
     1201 aatagaggtt tcaaaataga aatctgaatt atctgtatta ttacacaaaa atagaaacct
     1261 aaatttataa aaatagaata aagtttgtta tataaaatgt aattttgtct ataaaatctc
     1321 acctgttttc taactttaag cgtgaaaaag agaatgtatc atgaattttt tagttcatga
     1381 tgcatccttc tttgtatgaa atccaatata tctttattat ttaaacaatg gaaaagagtc
     1441 ttatttctat tttgagacat ctcttttatt taattatgaa gttttataca gttcaataaa
     1501 taggaattat atttagaaac tcatgacatt atttcttaga tagtgattaa atttatcata
     1561 ttccatttta gataactttt ctgggtaaga cattacaatc aggttatgcc cattaaattt
     1621 ttcatggtat ggtggatgaa tgtgttcata attatttgtc ttatatttta ctctttcata
     1681 gaacgccttg cgataaattg aaatctcatc aattggaagg tcaatttcta aaataatagt
     1741 ttttcctttc ttatttaaaa gctctaacgc tctttgtcca tatctattat tgcgcatttc
     1801 tggaaaaatg cagaaatgtt ctacatagat aaagtcatct gtttcccaac ataaaattat
     1861 gccgacaaac tggtttttat tataaattaa attgaattga tattctttat ttttcaaaat
     1921 ttcttcttgc aaagaagatt ttctttgttc atgaaatggg aaactaattt tatataattc
     1981 catagccttg taatataatt tattttcact ggttcttaac cgttcaaatt tcactttact
     2041 cctcctaatc acgaaaattc caatttattt atgagttcat tttaccatag tcagtatttg
     2101 catacaatgt gttttaagtt gagtgtcatt tctttctttt atttatgttt atatctcata
     2161 gactaagaga taattactta agacataact aaaaactatt atattaagct ttgataatct
     2221 aaaaacagta tatttatgga cttttctagg tctaaaagta atcttaataa ttttagaagt
     2281 tacaaaaaag ttacataaat ttggaaagct ataatataca tatataatat aaggttaaaa
     2341 ctgtaatgaa taatattaat ttaaaatttg aacatggaag gagattatta tggagaaaag
     2401 agaaaagagg ataataatat catctttatt aagtgtatca attttaatgg gtttggtaag
     2461 tatatattct atattaaata aagaagacat aattttaact gttaagggtc aagagcaaaa
     2521 agtatcttcc tttaagaaaa cagttgagga acttttggat gaacagggtg taaagtataa
     2581 ttctgaagat aagattaatc caagtttaga tacagaacta aaagatgata tgaaaataaa
     2641 agttgttaag gtaactaaaa gtaaaaaaga agagattgaa aaaattccat ttgatacaaa
     2701 gcatgtaaat gatagtaatt tgttaaaagg aaaatctaaa gtttatcaag aaggtcaaga
     2761 aggagaaaaa aaactagtct ataatttaac ttaccatgat ggaaagttag tcaaaaaagt
     2821 cttatcaaaa gaagtaatat ctaaggagcc aactacaaaa attataaaat atggaactaa
     2881 agaaaaagta ctaatagcat caagaggagc aaatataaga ggaggcaaac atatgaaagt
     2941 ggttgccact gcatatgcag gagatacaat aacatctact ggtacaactc caagatgggg
     3001 tgttattgca gttgacccac gtgtaatacc atatggaaca aaagtatata tacctaaact
     3061 gggtatgact tttgtagcag aagattgtgg aggtgcaatt aaaggtaata gaatagacat
     3121 ttttatgaac agtgaaggaa aagcttcaaa ttggggaagg aaaagtatag atatatatct
     3181 acattaaatt agtgaataga ataactttac ttgaaggaca aaaaagtata aaatatgaat
     3241 taactaaact gttagattat tcttaaaaca taaaaatata tctaaggggg gataagatga
     3301 aaatagtctg cttaggagac agtttaacgt atggatttgg ggtatcacga agtaattcat
     3361 ggacaaacat tgtaaataaa gagactcgat tagaaatagt aaataagggt ataaatggtg
     3421 atacaacaag tggtatgtta gctaggttta atgaagatgt tgtaaaaaac tctcctgata
     3481 tagtttttat aatgggtggc accaatgatt ttattgctgg tgcgggaaat aaaattatta
     3541 attctaatat aatggctatg gtgcatcagt catattcaaa aaatattata cctataatag
     3601 gtataccatt aaaaccagat attccaaatg ttagggaaga ttggagttgt tttactgatt
     3661 ttaatatagt atctcaaaac ttagaatcat atagttattg gataaaaaaa ttttgtatga
     3721 catttaatac taatttcgta gatttttatt cagaatataa taaaaatatg gaactagaag
     3781 gatataaaaa attatatttt gatgggttac atccaaccaa agagggtcat agaataatgg
     3841 catacatttt tattaattca attaataagt atatagaaga gttatagatt acattaaaat
     3901 gcttgtttat gcgtcagttg caataaatac atacagtaga gaggggttta ttatggatta
     3961 tactaaaact tatgaagagt ggataaaggg ttcatatttt gatgaagata caaagctaga
     4021 gttggagaat ataaaaaata atgaaaaaga aatagaggat agattctata aggatttaga
     4081 atttgggact gcgggtctta gaggaataat tgaagcagga acgaatagaa taaataagta
     4141 cacagttaga agagctactt ttggattggc aaactatata ttagaaaaca caacaaaaga
     4201 agaaacaagt agaggagtag taatagctca tgataataga cacaagtcta gacaattctg
     4261 tatagaatct gcaaatactt tggcagcatg tggtataaaa gcatatatat ttgatagttt
     4321 gagaactact ccagaattat cttttgctgt tagaagctta aatgcaatcg ctggtatagt
     4381 cataacagca agccataatc ctccagaata taatggatat aaggtatact gggaagatgg
     4441 agcacaagtt atgccagaga ttgcaaatgc aataacagag aaagtaaata gtatacatga
     4501 ttatagtaca ataccaacct taacggaagc taataaaaat ttggtagttt tgttggacga
     4561 atcacaagat actaaattta tagaagcagt aaaaagccaa attataagaa aagatttagt
     4621 taaaaatgta ggtaaaagct ttaagatagt ttatacacct ctttgtggaa cagggaatgt
     4681 tccaataaga agagcattga aagaagttgg ttttgaaaat ataattgtag ttccagaaga
     4741 agaaaatcca gacccaaatt ttgcagggct tgattatcca aatccagaag agaaaaaagc
     4801 tttaaataga ggtatattac tcgcaaaaga aaaaggagca gaccttgtaa tagcaactga
     4861 cccagattgt gatagagtag gtgtagcagt aaaaactact acaggtgagt atgctttact
     4921 tacaggaaat caaattggtg gtatgctgac acattatata atagaaggat taaaagaaaa
     4981 taataaatta aaagaaaatc ctacaataat aaaaaccata gttacatcag aatttggagc
     5041 agatatagct aaagcaaata atgttgatgt attaaatgtt cttacaggtt ttaaatttat
     5101 tggtgaaaaa ataaaattat ttgaacaaaa taaaaataga agttatgtat ttggatatga
     5161 agaaagttat ggttacttag ttgggactca tgctagagat aaagatggtg tagtttcttc
     5221 attgttaata tctgaaatgg cagcatttta ctattcaaaa ggtatgagtt tatatgatgg
     5281 tttaatagaa ctttataaaa agtatggatt tttcaaagaa cagactatat ctttgacttt
     5341 aaaaggtata gaaggtgtag aaaagataaa agaaataata tcttatttta gagaaaatca
     5401 aattgattat ataaatagta ttaaagtagt tgataaaaaa gattataaaa atggtataga
     5461 taatcttcct aaatctgatg ttttaaaata ctttttggaa gatgaatctt gggtagctat
     5521 aagaccatct ggaacagaac caaaacttaa attttacata gctgtaaaag gagctagtga
     5581 tattgaagca gataaaaaga ttcaaggttt gaaaaagtat atagatgaca tggtcgaaaa
     5641 attaaaataa aatattatta ttttataaga taattttgta ataatattta tttagctgaa
     5701 aattataatt tactttcatt gagtagaata tggaaatgtt agtagaattg ttattttcag
     5761 cttttatttg tgttattttt acttaaataa ttatattata gaatgaatct gagtataatt
     5821 aatattgtat aatgaaatta atttgataga aaaggggata tttatgtttg gtatagataa
     5881 gaaattgatt gaatatataa ttgcaaaatc caattacagt gaattaagtt caaagtcagc
     5941 agaagtatct ttcttcttaa tgttgtccat atttcctttt ttaatattta caataagttc
     6001 tatagcttat ataccgattc ttcatttaaa taagtatata gctttgttta gaaatatgat
     6061 gccagaaggt gcttttgctg tgttatcttc aatcatagtt tctgcaatag acaatagaaa
     6121 cctgaaattt ttagcagtca gttttgtact tactatgtgg acattttcaa gagcagtaaa
     6181 agctcttatt aaaggaatga atagagccta taaagttaaa gaaactaggt ctttttttaa
     6241 aattttatct atatcatttt tatttacaat aatgcttttg gtccttattt ttttatctat
     6301 gatattttta gtttacgggg aaaaaatagg ttattttatt tttaatcttg taggattgga
     6361 tgagatattt ataaaaatat gggatattct aagatacact gtaggtataa taacaataat
     6421 agtgatattt acacttttat ataaatacac tccaaataaa aagttaacta ttaaagaatc
     6481 tgcgccaggt gctatttttg ctacttttgc ttggttttta gtatcatttt tatattctta
     6541 ttatacaaat tactatgcta actatgaagt aatctatgga agtatagctg aaataattgt
     6601 acttatgacc tggatgtatt ttagtagttg gtctatcgtt attggctatg aggtaaattc
     6661 aagattgtat tttagaaaga taagacatga aatgttaaag taaagtattt aaaataaaag
     6721 agagtattta gtattataaa tgtaattgaa ttaataaaga aatattgaca tttaagttaa
     6781 aaagtctaga atttttctgg gcttttttta tttttagtat aacttgacaa attttattta
     6841 atgggatagt tttaatttat aatcatcttt aaaaagatga ctattgataa gtaagagata
     6901 aaattggtaa gtatcaaaaa atatactaaa taaaaattat agtcctaatg agttaatttc
     6961 tgtattttca aataatgcag tatttagtca tgtgttttta tatgtgcctg tatttctaat
     7021 taccaatata ttagaataag ctactgtaat tagatttaga aaaaagcgac ataaataatt
     7081 ataaacaaat aataaattac ataaaattaa
//
LOCUS       DAMJXI010000122         6693 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.129, whole genome shotgun sequence.
ACCESSION   DAMJXI010000122 DAMJXI010000000
VERSION     DAMJXI010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6693
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.129"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            364..1638
                     /locus_tag="PC465_003584"
     CDS             364..1638
                     /locus_tag="PC465_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HDF2650852.1"
                     /translation="MQFMDVSKYIEGANLKVKTKNGETVKRIYFNNSATPLVLKNVID
                     NLNCEIPWLTYINAPGIISEKNTLKYENVRSTILKLIDGDEEKDSVIYVKNATEGINF
                     LAKFFKDENPDKFVITTAMEHMANYLPFKVNFPTKVVGITEKGELDLCQLENIFKNYA
                     GNVPLVTVTGASNVTGITTPIYEIARIAHKYGAKILVDIVQVIQHKPFSMMPHECDEH
                     IDFVVFSAHKCYSPLNGGALVGPKKFFEKFNPVLYGSGSTKFVNDNKILYANVPQRFE
                     AGYPEYFGTLAMGKALNTLNKIGLNRISKYERELFLYAKEEMSKIPNIIIYGDKSNNV
                     IIPNISFNISNMYYKDVAKYLVDNFGIETGAGVVGADIYVQKLLGINPKEAYVRFMRE
                     NPVGLVRISLGMYNTFDEVDSFIHAIKTLAFK"
     gene            complement(1845..2162)
                     /gene="trxA"
                     /locus_tag="PC465_003585"
     CDS             complement(1845..2162)
                     /gene="trxA"
                     /locus_tag="PC465_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HDF2650853.1"
                     /translation="MVKIINNNEFINEVENKDGLVVVDFFATWCGPCKMLSPIYEALG
                     NEMVEKANFLKVDIDQSIELAQKFEVSTVPTMLIFKDGKPVDRLIGFMPKENLKNKIE
                     SYM"
     gene            2429..3181
                     /locus_tag="PC465_003586"
     CDS             2429..3181
                     /locus_tag="PC465_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HDF2650854.1"
                     /translation="MDNIINELQNIGFTKYESQIYISLLKESPLTGYEISKLSGVPQS
                     KVYENITKLLNNNIIINVGTDPIKYIPINPNELLKNKKKEFDNSMDNLKNSLQILNKS
                     KSVEYVLNIKGEKNILKKAIEMIKNAKQEIIISCPYEEILELKKELLIAYKKNINIEI
                     LLLENKSLKGLDNIHIHGGNKTTLENKMLYKGIILIVDNDEILTGNLSEGSEAISIWT
                     KNSNILYIGVQYIKHEIYISEQIKGGYKNEQN"
     gene            3168..4049
                     /locus_tag="PC465_003587"
     CDS             3168..4049
                     /locus_tag="PC465_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HDF2650855.1"
                     /translation="MNKIKIKQVDAFTTIPFGGNPAGVVTDASNISDEIKQNVAKEMN
                     LSETAFVSESNIADFKVQFFTPGLEVDLCGHATIGTFHALLEEGKLNTNKSIFYQETK
                     AGVLSVELKKINNENIFMMEQNTPEFENLDNCRKELAQMIGVHEDRLLEYPIIKVNTG
                     LWWLVFGLKSLDDLKNISPDLNKIKKFSGDNNIIGITPFCIETIDKKCDYHLRSIAPY
                     VGVTEDPVCGTGNACVSSYIVHHNILDKTSFIGEQGNFINRPGKVYVNITRENNDITS
                     VKIGGSAYTVLSGEIMY"
     gene            complement(4275..5630)
                     /locus_tag="PC465_003588"
     CDS             complement(4275..5630)
                     /locus_tag="PC465_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDF2650856.1"
                     /translation="MSSTVKKKGKFPMGFYICSTTFSFERAAYYASKYLIYIFLTTAI
                     VHGGLGIDKGQAAIMQANLVAFTYLAPIIGGYISDRWIGARYTIPIGMLIMGVGYYLG
                     SIATTVSMVNAMIILVSIGTAFFKGNVSAVNGQLFDSQEELDTAFSVQYSFVNIGSFI
                     GTIAVGILYLKTFAKNGVLGFSQCFFIAAVLCVIGAIWFIYGWRFLGNAGKRPFKEGV
                     VAEKIEEKDKSPLTSMDKKRIWAIILISFFSVIFWVFWYLTYLAVYDYGAAFVNMNVG
                     GFDVPLAWFDSLNSLVCIVLGPVLGALWFKLASRPQGDMSLFKKTGLGLIFLGLAFLM
                     LVGAEFSRGVGAPETAKASILWIIMFGILLSLGEMLFSPLGNSFVSKYAPKKLLGVLM
                     GVWTFATFIAGKGYGYIYAFTLKFDMIKVYTIIPVILFVAAILLFLSDKTLSRLVEDD
                     K"
BASE COUNT         2581 a          948 c          838 g         2326 t
ORIGIN      
        1 attatgttct aatcaatttc tttactattt ttacaacttt attagtcata ttcataatta
       61 tttctaatta gtgtttaaca ttttatgtaa aatttataaa aaaatgtata taaattaaaa
      121 taagtgacta tactaaaaat atgatacgga taaacaataa gttcaaccta tctcccccaa
      181 aatcaagtga gctacagttt cccccaactg tagctcattt tcgtgtaatt taataaacat
      241 ctcaacaaga attaattaac gaaacccctt ataaaaacat aacatatatt aaacaagctc
      301 ttgattaaaa cttgagcttt tttaataaaa aacagaatag tttattagat aaggggtttt
      361 tttatgcaat tcatggatgt atctaaatac attgaaggtg caaatcttaa agttaaaact
      421 aaaaatggtg aaactgttaa aagaatatat tttaacaact ctgccactcc attagtttta
      481 aaaaacgtaa tagataactt aaactgtgag attccttggc ttacttatat taatgctcca
      541 ggaataatct cagaaaaaaa tactttaaaa tatgaaaatg tacgctctac tatcctcaaa
      601 cttattgatg gagacgaaga aaaggattct gttatttatg tcaaaaatgc tacagaagga
      661 ataaacttct tagcaaaatt ttttaaagat gaaaatccag ataaatttgt tattaccaca
      721 gcaatggagc atatggctaa ttacctgcct tttaaagtta attttcctac aaaagttgtt
      781 ggaattacag aaaaaggaga acttgattta tgtcaattag agaatatatt taaaaattat
      841 gctggtaatg tacctctcgt tacagttaca ggagctagta atgtcacagg tataaccact
      901 cctatatatg aaatagcaag aatagctcat aagtatggtg caaagatatt ggtggatatt
      961 gtgcaagtaa ttcagcataa acctttttca atgatgccac atgaatgtga tgagcatata
     1021 gattttgttg tttttagtgc tcataaatgt tattctccac taaatggagg agctctggta
     1081 ggacctaaaa aattctttga aaaatttaat cctgtactat atggctcagg ttctaccaaa
     1141 tttgtaaatg ataacaaaat actatatgca aacgtacccc aacgttttga agcaggatac
     1201 ccagagtatt ttggaactct tgcaatggga aaagcactga acactttaaa taaaattggt
     1261 ctaaacagaa tttcaaaata cgaaagagaa ttatttttat atgctaaaga agaaatgagt
     1321 aaaataccta atataataat atatggagat aaatcaaata atgtaattat cccaaatata
     1381 tcttttaata taagtaatat gtattacaaa gatgtagcaa aatatttagt tgataacttt
     1441 ggaatagaaa ctggagctgg agtagtaggt gcagatattt atgtacaaaa attattaggt
     1501 ataaatccaa aagaggcata cgtcagattt atgagggaaa atcctgtagg tcttgttagg
     1561 ataagcttag gaatgtacaa tacttttgat gaggtggata gctttataca tgctattaaa
     1621 actttggctt ttaaataagc tttttctatt cttttttatc aataaataga gagtagtttt
     1681 gttttcacaa aaaagcaaat tatatcaaca gtcaatttca ttagcaatta gacactcatt
     1741 tgtaactata caaactattt tacactatac aaacaaaaaa ctcattacaa tgagtttttt
     1801 tgtttatata tgagatttat tttaattact tcaatttact ttaattacat atatgattca
     1861 attttgtttt ttaaattctc cttaggcata aaacctatta atctatctac aggttttcca
     1921 tccttaaata ttagcatagt tggtactgta gatacttcaa atttctgagc taattctata
     1981 ctttggtcta tgtccacctt caagaagttt gctttttcaa ccatctcatt tcctaaagct
     2041 tcatatattg gtgatagcat cttacaaggt ccacaccaag tcgcaaagaa atctacaact
     2101 actaaaccat ctttattttc tacttcattt ataaattcat tattatttat tatttttacc
     2161 ataatataca tctcctttat tatcttcttg atattaatat actacgccct atataacagt
     2221 tcaattaggc acttttttgt aaccgcctat ttttaatagg tttaatatta tgataaatag
     2281 atttataaga ttaaatattt ataagactaa atatttctaa tatattttat ttttttctta
     2341 atatagttga cattttttcc cttaaattat aaaatcaaat taataactac ataggtagtt
     2401 actaatcttt tatcaaagga gtttctatat ggataatata attaatgaat tacaaaatat
     2461 aggatttact aaatacgaat ctcaaatata catatcatta ttaaaggaaa gccctttaac
     2521 aggatatgaa ataagtaaat tatcaggtgt accacaatca aaagtctatg aaaatataac
     2581 aaagctatta aacaataata taattatcaa tgttggaact gaccctatta agtacatacc
     2641 aataaaccct aatgaattat taaaaaataa gaaaaaagaa tttgacaatt ctatggataa
     2701 tctaaagaat agcttacaga tattaaataa aagtaaaagt gtagaatatg ttttaaacat
     2761 aaaaggagaa aaaaatatat taaaaaaagc aatagaaatg ataaaaaatg caaaacaaga
     2821 aattataatt tcttgccctt atgaagaaat tcttgaatta aaaaaagaac tcctaattgc
     2881 ttacaaaaaa aatattaata ttgaaatact acttttagaa aacaaaagtc tgaaaggtct
     2941 tgataatatt catattcatg gaggtaataa aactacactt gaaaataaaa tgctttacaa
     3001 aggaattatt ttgattgtag ataatgatga aatattgaca ggaaacttat cagaaggcag
     3061 tgaggccatt tcaatttgga caaaaaactc taacatttta tatattggag ttcaatacat
     3121 aaaacatgaa atttatattt cagaacaaat aaaaggaggt tataaaaatg aacaaaatta
     3181 agattaaaca agttgatgct tttacaacta taccttttgg tggaaatcct gctggtgtcg
     3241 ttactgatgc ctctaacatt tctgatgaaa ttaagcagaa tgtggctaaa gaaatgaatt
     3301 tatcagaaac tgcatttgtt tcagagtcaa atattgcaga ttttaaagta caatttttca
     3361 caccaggttt agaagttgat ttatgtggtc atgcaacaat aggtactttc catgcacttt
     3421 tggaagaagg gaagcttaat actaataaga gtatatttta tcaagaaaca aaagctggtg
     3481 tattatctgt agagcttaag aaaataaata atgaaaatat atttatgatg gaacagaata
     3541 cacctgaatt tgaaaattta gataattgca gaaaagaact tgcacaaatg ataggtgtgc
     3601 atgaagatag acttcttgaa tatcctatta taaaggtaaa tactggactt tggtggcttg
     3661 tatttggtct aaaatcttta gatgatttaa aaaatatctc tccagattta aataaaatca
     3721 aaaaatttag tggtgataat aatataattg gtataactcc attttgtata gaaactatag
     3781 ataaaaagtg tgactaccat ttaagatcta tagcaccata tgttggagtt acagaagacc
     3841 ctgtatgtgg aactgggaac gcttgcgtat catcttatat agtacatcac aatattttag
     3901 ataaaactag ttttattggt gagcaaggta actttataaa cagacctgga aaggtatatg
     3961 taaatataac tagagaaaac aatgacataa cttctgtaaa aattggagga agtgcttata
     4021 ctgttttaag tggtgaaatt atgtattaat cccataccta ataaaaacaa ataaaaatac
     4081 tagctaacta aagctagtat ttttatttgt tatttttatt taataatcat actctaacaa
     4141 atattataat tatatatatc ataatattgt atttagaagt aaaattttat ttttattatt
     4201 aattagttat aaatcaatct aatacaacat aattacagta gattaaccta taaaacataa
     4261 taattgctta ctaattattt atcatcctca acaagtctac ttaatgtctt atcagataag
     4321 aataataata tcgctgcaac aaatagtatt actggaatta tagtatatac tttaatcata
     4381 tcaaatttaa gagtaaatgc atatatatat ccatatcctt taccagctat aaaagtagca
     4441 aatgtccata ctcccataag aacacctaga agcttcttag gtgcatactt acttacaaaa
     4501 gagttaccaa gtggtgagaa taacatttca ccaagactta aaagaatacc aaacatgatt
     4561 atccatagta tactagcttt agcagtttca ggagctccaa ctcctcttga aaattctgca
     4621 ccaacaagca ttaagaatgc aagacctaag aatattaatc caagacctgt ctttttaaat
     4681 aaactcatat ctccttgtgg tctactagca agtttaaacc ataatgctcc aagaactggt
     4741 cctaatacta tacatacaag tgaatttaat gagtcaaacc aagcaagagg aacatcaaat
     4801 cctccaacat tcatgtttac aaatgctgca ccataatcat aaactgcaag ataagttaga
     4861 taccagaata cccagaaaat tacagagaag aatgatataa gtataatagc ccaaattctc
     4921 ttcttatcca tgcttgtaag aggagactta tctttttctt caattttttc agcaactaca
     4981 ccttctttaa aaggtctctt tcctgcattc ccaaggaatc tccatccata tatgaaccat
     5041 attgcaccta ttacacaaag tacagctgct ataaagaaac attgagaaaa tccaagtaca
     5101 ccattttttg caaatgtttt aaggtaaaga ataccaactg ctatagtacc aataaaagaa
     5161 cctatattaa caaaagaata ctgtactgaa aatgctgtat caagttcttc ttgactatca
     5221 aaaagctgtc catttaccgc agatacgtta cctttaaaga atgcagtacc aattgaaact
     5281 aagattatca ttgcatttac catagaaact gtagttgcaa tagaaccaag atagtatcct
     5341 actcccatga taagcatacc tataggtata gtatatctag ctcctatcca tctatctgat
     5401 atatatcccc caattatagg tgcaaggtat gtgaatgcaa caaggttggc ttgcattata
     5461 gcagcttgtc ctttatctat tccaagacca ccatgaacta tagctgttgt aaggaatata
     5521 tatattaagt actttgaagc ataatatgct gctctttcaa atgagaaagt tgttgagcag
     5581 atataaaatc ccataggaaa tttacccttc ttttttactg ttgagctcat aattttaaat
     5641 cctttcttaa ttgtattttt attttttacg ttttgtccaa attctttctt ttatgaaaga
     5701 tataatatta ttattttgta aaacaatttg taattattat taagataatt gcgcatttat
     5761 ttgtagagta catattctca tggaataaaa ttaatacact tcttaatcat aaatttaaat
     5821 tatataaatt cactattttc agatatagtt ataaattaat atattctcat ctaataccat
     5881 gaaaaaacct tcgccatatg caattcttat tttttacgtg atagtatttt acaaactaaa
     5941 atcccccttt tgtagcaact tatgtaatta cattttagtg cttttttaaa ggagtctcga
     6001 ataaagcaac atatattttg ttcaaataat gtttttattt attttttaaa tttatatatt
     6061 acttcaccca accaattctc aacttaaata actaaactac tatctattca cagattaggc
     6121 ttatttctta cacattagtt tataataaac actgtgaatc taaacataaa aactgttatt
     6181 ttaaagtaat tacccatata ttcgctttga tactatttat tgaggttata ctctttatgt
     6241 ataatatatt atttataaaa tacctcaaaa tatattattc ataaaatacc tcaaactgaa
     6301 aactttttca cgaatattta tttttcacct cccctttttt atttcaccat gtaaatcgta
     6361 ccataaatat gcacttatat gcaagaaaaa aatctattaa tcgacagtaa ataattagaa
     6421 aaattcaaat tatatttatc aagtatatta tataaaatat ttcctatgaa aatataaatt
     6481 aaattaatgt tcagaattgt ttttagatat gaaatcttga tttttttatt actttactta
     6541 tttgctcaaa tatatttttg tatgcagtat ataataatca aattatacac ttcttataac
     6601 tgcattgatt tgaaaataat attaataatt aatagaataa aaaatttaaa ttaaatttaa
     6661 aaaaatttgt taagttgatt gaatactttt tta
//
LOCUS       DAMJXI010000123         6692 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.130, whole genome shotgun sequence.
ACCESSION   DAMJXI010000123 DAMJXI010000000
VERSION     DAMJXI010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6692
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.130"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     misc_binding    365..603
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            667..2586
                     /gene="thrS"
                     /locus_tag="PC465_003589"
     CDS             667..2586
                     /gene="thrS"
                     /locus_tag="PC465_003589"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HDF2650857.1"
                     /translation="MIKVALKDGSIKEFENAISVMDVAKSISEGLARNVVAASVNGEV
                     VGLDHIIDTDCDLNLFKFEDKEGKEVFRHTSAHILAQAIKRLYPEAKLAIGPSIENGF
                     YYDIDLDHRLVPEDLEKIEAEMKKIAKEDLKIERFELPRNEALELMKEQGEDYKVELI
                     SDLPESEIISFYKQGDFTDLCRGPHLPSTKKVKAVKLQSVAGAYWRGDENNKMLQRIY
                     GTSFEKNKDLEEYLHLLEEAKKRDHRKLGKELGLFMIPEEGPGFPMFLPKGMELKNEL
                     LKFWREIHRKAGYIEIESPIILNRKLWETSGHWYHYKENMYTVKIDDEDYAIKPMNCP
                     GGLIYYNSQLHSYRDFPMRVAELGRVHRHELSGALQGLMRVRAFTQDDSHIFMLPEQI
                     KDEIKGVANLIDGIYKTFGFEYNLELSTRPENSMGSDEEWEAAENGLREALEELGLPY
                     TINEGDGAFYGPKIDFHLKDCLGRTWQCGTIQLDMQLPRQFDNTYIGQDGEKHRPVMI
                     HRVAFGSIERFIGILIEHYAGKFPVWLSPTQVKILPISDKFMDYANEVKKELFDKGIR
                     VELDDRAEKIGFKIREAQLEKVPYMLIVGEKEVADNNVSVRSRDKGEIGSIKLDEFIA
                     SISKEIESRESIIQD"
     gene            3354..4445
                     /locus_tag="PC465_003590"
     CDS             3354..4445
                     /locus_tag="PC465_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDF2650858.1"
                     /translation="MIEKVEEKSKIIKTSKEYKRTIIEEKDKEWTKKLNDILSRSSFS
                     NDELDKIKALIPKEILTNENVGEVVTEDGYAKPEYDEVFKSLFTLNNEYDLLVNFIND
                     ILKDAPYANRNIKPFTQIKRIIRVETDPTINYIGEKRPRLDILAEDEENNHINIEMQR
                     AFENDYLERAEYYLSRVHGRKLEEGKEYKEIGKTIGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIYSSKTALYFIELPKIHKSDYIVNRIMLWGKLISNPSSLDVRVIAKNDSIIK
                     KALDRLKELGSNEEYLLNLKRGAYIMNKSRNFKEEIERETAIRVAKEKDYKIIIMLKK
                     NGFKLDDILNKFNDFDLSEDEIKEVYENN"
     gene            5111..6451
                     /locus_tag="PC465_003591"
     CDS             5111..6451
                     /locus_tag="PC465_003591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2650859.1"
                     /translation="MIKSSLFWNIFIAISFMIEWFLCKKMLDYTSEKRISNKKINFCM
                     VGIIVFADIIYFFDVPPNIRVIISMIITIAFYKISYDVRFIKSVLISLIYWMLLIATD
                     ALSISLTVWLNSINDMSSMGTGDIYRIESIILGKILLIVSLLLYRALKIKLNIEINKR
                     TLFYIVIPIVANIASFFVIFEYIFNPGSGSLIHNFQFVMISVVLLISSITLVLIAKKL
                     QQYNTLVVENNMIKNTLKYENEYYEDIEKKYLKTRLLSHDMKNHILCINAMIKKGIDV
                     TSYLNNLQVEIQSNDLLFNTGNFILDAILSEKKEVCDKNDIELKIGINFSCCEAVELV
                     DICHIFSNILDNAIEACNKIDSGNRVICVKGDVMQNFYLIRVENTKMNKIITKNGDIL
                     TDKKGSLHGLGIKSVKNSVNKYGGNVVIEYDDKKFVVKIAIPLRNVKKAVNHVI"
BASE COUNT         2648 a          608 c         1153 g         2283 t
ORIGIN      
        1 ttatttgatt gtgttactta ttaatagtat ttaagtattt actgtactac ttattaacta
       61 tattaagtat tgattgtatt taagtataca aaacctaaaa agagtacaaa aattagaagt
      121 tagttttaat aaaaattagt tttagtattt atctagtcat atctatcatg catgtggata
      181 cgttttaaaa attttaaatt tatgaaaata ttataatatc actataaatc aagagattaa
      241 tttaatataa aaatataaga atattggttt acagctgatt gagatgaaaa ataatgggta
      301 attaatatat tacattaatg ttgattgatg tataactatc tgttataatg aaaatatatt
      361 aaaaatcata gtgttgaaga ggaagagtag agtagaaacc attctcagag aatttgggtc
      421 tatggctgag agcccatgta ataggtctat ttgaaaacta ccttggagct gagcttatta
      481 gcagtatttg tatttgtact atacgtgaaa gtgctcgggt gacgacctta tagtcatcaa
      541 gagggttgta tatacttgta tacgccaact tgggtggaac cgcgaattaa tatcgtccca
      601 aacatatttg gggcgatttt ttattacaaa aaatctaaaa attatttcaa taaggaggaa
      661 aaaataatga ttaaagttgc tttaaaagat ggctcaataa aagaatttga aaatgctatt
      721 tctgttatgg atgtagctaa atccattagt gaaggattag ctagaaatgt ggtagcagcg
      781 tctgtgaacg gagaggttgt aggtctggac cacattatag atactgattg tgacttgaat
      841 ttatttaagt ttgaagataa agaaggtaag gaagttttta gacatacatc agcgcatata
      901 ttagctcaag ctataaaaag actttaccca gaagcaaagc ttgctatagg accaagtata
      961 gaaaatggat tctactatga tatagattta gaccatagat tagttccaga ggacctagag
     1021 aaaatagaag ctgaaatgaa aaaaatagct aaagaagatt taaaaataga aagatttgaa
     1081 cttcctagaa atgaagcttt agagcttatg aaagaacaag gagaagacta taaggtagaa
     1141 cttatatctg atttacctga aagtgaaata atatctttct acaagcaagg tgattttact
     1201 gatttatgta gaggaccaca tttaccatct actaaaaagg taaaagctgt taaattacaa
     1261 agtgtagcag gtgcatattg gcgtggtgac gaaaataata agatgcttca aagaatatat
     1321 ggaacttctt ttgagaaaaa caaagactta gaagagtact tacatttact agaagaagct
     1381 aaaaagagag accacagaaa attaggtaaa gaattaggat tatttatgat acctgaagaa
     1441 ggtccaggat tccctatgtt tttaccaaaa ggtatggaac ttaaaaatga attattaaaa
     1501 ttctggagag aaatacacag aaaagctgga tatattgaga tagaatctcc aatcatatta
     1561 aatagaaaat tatgggagac ttcaggacac tggtatcatt acaaagaaaa tatgtataca
     1621 gttaaaatag atgatgagga ttatgctata aaacctatga actgtcctgg tggattaatt
     1681 tactataact ctcaactaca ttcatataga gatttcccaa tgagagttgc agagcttggt
     1741 agagttcata gacatgagtt atctggtgca ttacaaggat taatgagagt tagagcattt
     1801 actcaagacg attcacatat attcatgtta ccagagcaaa ttaaggacga aataaaagga
     1861 gtagctaact taatagatgg tatctacaaa acttttggat ttgaatataa tttagaatta
     1921 tctacaagac cagagaactc tatgggaagc gacgaagagt gggaagcagc agaaaatgga
     1981 ttaagagaag ctttagaaga gttaggtcta ccatatacta ttaatgaggg tgatggagca
     2041 ttctatggtc ctaagataga cttccatcta aaagattgtt taggaagaac ttggcaatgt
     2101 ggtactatcc aattagatat gcaacttcca agacaatttg ataatactta tattggtcaa
     2161 gatggtgaaa agcatagacc agttatgatt catagggttg cttttggtag tatagaaaga
     2221 tttataggta tattaataga gcattatgct ggtaaattcc cagtttggtt atctccaact
     2281 caagttaaga tacttcctat atctgataaa tttatggatt atgcaaatga agttaagaaa
     2341 gagttatttg ataagggtat aagagttgaa ttagatgata gagctgaaaa aattggattt
     2401 aagataagag aagctcagct tgaaaaagtg ccatacatgt taatagtagg tgaaaaagaa
     2461 gtagctgata ataatgtttc tgttagatca agagataaag gtgaaatagg tagtattaaa
     2521 ttagatgaat ttatagctag tatttcaaaa gaaattgaat caagagaaag tattattcaa
     2581 gactaatata tattatttta gtagctaaga tattgttata taagataagt ttaatcaata
     2641 tgttgatatg ttgatgcata gtgattaaat ttatgaaaag atgagtataa ttagaggtac
     2701 agttaatcat atttttatga ttaatgtacc tctagttttt tgtatggtag atttattaat
     2761 aaatatatca tagaagtgtt ttgaacaagg aaatatttat gtgcattctt taaataaaag
     2821 tttatttttt gagtgataat taagtgcttg ttggtaaggt tatggctgta aaaatcataa
     2881 ctttattttc atatttgttc cattttcata aaaattatta tacctttaag aaaatttctt
     2941 aatcctcttg aaatatttcc tttttagtct aaagttaaat ttctttcttc aaaatgaata
     3001 tttaaatgaa ctaaaattta agtacatttt ctaatcttat gagtctattt ttcatagata
     3061 attgccctat aatagaagaa tctatgttgg tgctatgtgg tgacaataac agcattgtca
     3121 gtgattaatt aatgctttat aaatgattaa ttagtgtttt atgttatttt tggacttacc
     3181 ctctatacat agattaattt atttaacttt agatagagag agaatgtcaa gtacatacac
     3241 agacattaga gtttaagaaa gtgtttatgg agcaagaact tttaaaagag gtagtgactt
     3301 agtttaattt caagaaatga taaatacaaa agaggaaaaa gagaggtgtt gaaatgatag
     3361 aaaaagtaga agaaaaatct aagattatta aaacatcaaa agaatataag cgaactataa
     3421 ttgaagaaaa agataaagaa tggaccaaaa aattaaatga tatacttagt agaagtagtt
     3481 tttctaatga tgaattagat aaaatcaagg cgttaattcc aaaagagatt ttgactaatg
     3541 aaaatgttgg agaagttgtg actgaagatg gatatgctaa gcccgagtat gatgaggtat
     3601 ttaaatcatt gttcacttta aataatgaat atgatttact tgtaaatttt ataaatgata
     3661 tcctaaaaga tgctccatat gctaacagga atatcaaacc gttcactcaa ataaagagaa
     3721 taattagagt tgaaactgac ccaacaatta attacattgg agagaaaaga cctagacttg
     3781 atattttggc tgaagatgaa gaaaataatc atataaatat tgagatgcaa agagcttttg
     3841 agaacgatta tttggaaaga gctgaatatt atcttagtcg tgtacatggt agaaagttag
     3901 aagaaggtaa agagtataaa gaaattggaa aaactattgg aatacatata ctaaatcatg
     3961 taaaatataa tcacatagaa gattatgtaa attgcctgag attaacaatg gacgggcatc
     4021 cagatattta ttctagtaaa actgcattat attttataga gcttccaaaa attcataaat
     4081 ctgactatat agtaaataga attatgctat ggggaaaact tattagtaat ccttctagct
     4141 tagatgtaag agttatagct aagaatgatt ctattattaa aaaagcactt gatagattaa
     4201 aagaattagg tagcaatgaa gaatatttat taaatctgaa aagaggtgct tatatcatga
     4261 ataaaagtag aaattttaaa gaagagattg aaagagagac agcaattaga gttgcaaaag
     4321 aaaaagatta taaaataatt ataatgttga aaaaaaatgg ttttaaatta gatgacatat
     4381 taaataaatt taatgatttt gacttaagtg aagatgagat aaaagaagta tatgaaaata
     4441 attgatgata aaaagtgaac ttatataagt ttgctgaatc ggagtctgga aatatttatg
     4501 tgtatttttt aatgaataaa aatttatttt aaaaacaata atttagaggt acagttaatt
     4561 atatttttat gatactgtac ttctagtttt ttctattgta gatttattat ttactaataa
     4621 atctacaata gaagtgcttt tgttgtaaga atcattttat ctaatgattg ttttttataa
     4681 tagttaaatt tccatttgta gtgtttaaat ataaatctat aacagcattt ctataaatgt
     4741 tataaatcac tataatgatt caactcaaag ttactgctta aagaagcaga gattttatca
     4801 aggtatatca tggaaaaaaa tattttattg taatatttat aagattttat tatggaaata
     4861 atgtaaaaac tttataaata atatatttta tacctagtta tagataaatt tatatagtta
     4921 ttattaaaaa aagcaataaa aagtttaatt caatttagca aatttagtga tataattaaa
     4981 aaagaaaaga aatatggact tatttggaat aattttgaca atctatttac tacacgtgta
     5041 gagtcgtata taattaaatt atacataaaa tataaaaaaa taatttagta atacgttagg
     5101 agaaagtatt atgataaagt caagcttatt ttggaatatt ttcattgcga tatcctttat
     5161 gatagaatgg tttctttgta agaaaatgct agattataca agtgagaaaa ggatttctaa
     5221 caaaaaaata aacttttgta tggtaggtat tattgttttt gctgacataa tatatttttt
     5281 tgatgtacct ccaaatataa gagtaattat atctatgata attactattg cattttataa
     5341 aatctcatat gatgtgaggt ttataaagtc tgtattaata tccttaattt attggatgtt
     5401 actaatcgcc acagatgctt tgagtatatc tttaacagtt tggcttaatt ctataaatga
     5461 catgagtagt atggggacgg gagatatata cagaattgag tctataatat tgggaaagat
     5521 acttttgatt gtgtctttgc ttttatatag agccttaaag ataaaactta atatagaaat
     5581 aaataaaagg acattatttt atatagttat tcctatagtc gctaatatag catctttttt
     5641 tgtaattttt gaatacatat ttaatccagg gtctggtagc ttaatacata atttccaatt
     5701 cgttatgatt tctgttgtat tgcttatatc aagtatcact ttagttttaa ttgctaaaaa
     5761 attacagcaa tataatactt tagttgtaga aaacaatatg attaaaaata ctttgaagta
     5821 tgaaaatgag tattatgaag atatagaaaa gaaatattta aaaactagat tactaagtca
     5881 tgatatgaaa aatcacatat tgtgtataaa tgctatgatt aaaaaaggta ttgatgttac
     5941 ttcttattta aataatttgc aggtagaaat tcagagtaat gacttgttat ttaatactgg
     6001 taattttata ttagatgcta tattaagtga aaagaaagag gtttgtgata agaatgatat
     6061 agaactaaaa ataggaataa attttagttg ttgtgaagct gttgaattag tggatatatg
     6121 tcatatattt tcaaatattt tagacaatgc aattgaggca tgtaataaaa ttgatagtgg
     6181 aaatagagtt atttgtgtta aaggtgatgt tatgcaaaat ttttatttaa taagagttga
     6241 aaatactaag atgaataaga ttattactaa aaatggagat attttgacag acaaaaaagg
     6301 ttctcttcat ggacttggaa taaaaagtgt aaaaaactct gtaaataagt atggtggtaa
     6361 tgttgtaatt gaatatgatg ataaaaaatt tgtagttaaa attgctattc cacttagaaa
     6421 tgtgaagaaa gcagttaatc atgtgattta aatgtatata aatttgatgt gtagaaattt
     6481 aatatataag aattaatgta taaaagtgat gcatagaagt ttaatatata agaattaatg
     6541 tataaaagtg atgtatagaa gtttaatata taggaattta ataagtataa aagtgatgca
     6601 tagaaattta atatataaga atttaatatg tataaatgtg gtgcatagaa gtttaatgta
     6661 aaaatttggt gtataagaat ttaatatata ta
//
LOCUS       DAMJXI010000124         6615 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.131, whole genome shotgun sequence.
ACCESSION   DAMJXI010000124 DAMJXI010000000
VERSION     DAMJXI010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6615
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.131"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(21..734)
                     /locus_tag="PC465_003592"
     CDS             complement(21..734)
                     /locus_tag="PC465_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2140 domain-containing protein"
                     /protein_id="HDF2650860.1"
                     /translation="MGKVAKILLSLIVIVLVLAGIVVYILTPKERYDVSSQNNKIIDE
                     EYLSKGSYINSMEVVKNPLRMVGKISVSEEEFKNLIYTLMQKHGINELENNFVEMKNG
                     KIKVAGPYKVFGLVNSQYELELRPTLKDGNLVVSLENVKIGKFKLSDKMLEKILSNYN
                     KKVPFEVNGNKITLEKSYLYPITLKNISIKKGNVDLDMEVEIDLKSQINGALGYLKDS
                     GKVQDILNHLINLKKTSVG"
     gene            1026..2690
                     /locus_tag="PC465_003593"
     CDS             1026..2690
                     /locus_tag="PC465_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HDF2650861.1"
                     /translation="MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHA
                     KSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYF
                     DEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
                     NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIED
                     AIEGITHSICTLEFEDQRPLYDWFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLV
                     DEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENL
                     QPKAPLTMGVLRPLKLIITNYPEDKIEMLEIENNAKDESQGKRLVPFSRELYIEQDDF
                     MEEPVKKYFRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGR
                     KVKSTIHWVDAKSAIPCEFRLFEPLILDDIPENEGKHFLEQINPNSLEILQGFVEPTQ
                     IKDAKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPGK"
     gene            complement(2797..3696)
                     /locus_tag="PC465_003594"
     CDS             complement(2797..3696)
                     /locus_tag="PC465_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HDF2650862.1"
                     /translation="MKKVKLIYNPNSGEKKILSNLDTIIELYQEKNYLLIPYRLTIKE
                     PVKNAFKEVDSSYEHILIAGGDGTVDLVVNAMKELDIKIPIGILPTGTANDFSNALQI
                     SFDIKEAINEIINSKPKKIDIGKVNNKYFINVASAGMFTDVSQRINTDLKNSFGRISY
                     YIKGIEEALYMRKFKIKVSSEEMYYDGDMYLMLIFNGKTAGNINLAYKAEIDDGYLDV
                     IIFKGMPIPKSIPVLISVLRGDYLDQYNGNEILYFKTKKVHIECEDSLITDIDGEKGP
                     DFPLNIECIKDGIEVMGICSEKS"
     gene            complement(3723..4361)
                     /locus_tag="PC465_003595"
     CDS             complement(3723..4361)
                     /locus_tag="PC465_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003356606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HDF2650863.1"
                     /translation="MDQNLNWLNEKRIEKTIKSLENNNMKGYLVSNKEELLKKIEEIV
                     KAGSLVGCGGSMTLFETGVIDFIREKYNFLDRYAKDIKPEEMKEIYRKSFSADAYFTS
                     TNAITEDGELYNLDGNGNRVAAMIYGPDKVIVIAGVNKIVKDVDEAIKRTKTIAAPAN
                     CKRLSTNTGCKTTGICIDCSSPGRICCSYTLIKRQLTPERIHVIFLNEDFGY"
     gene            complement(4698..5696)
                     /locus_tag="PC465_003596"
     CDS             complement(4698..5696)
                     /locus_tag="PC465_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4003 domain-containing protein"
                     /protein_id="HDF2650864.1"
                     /translation="MEQSFINGKVNLLIENYKALNEVKGSWQMGLIQHSCALAFTLKN
                     KRISPRLVEERIELIKKNTGLFSNFRGYNMFYMATLLSFESNPESSFKMILDIYKELK
                     SEKFWGDTYLPLTASIVYENREKMDYLTCISKMKIIYDYMRKKHPFLTSSDDYCNIAL
                     IAIHSKNLDEDLEYIEKCYEFLNENGFYKGNDLQALSQILLFSDDRTMLKCKKTIELK
                     KAFKENDCKMNYYGYPIIGAISLLDYREDEIIEEIKNVSNKLKEEKGFGNWSLGKSNR
                     VMISSAIVASIYADLIRNENNIGSITNNIFLNIVVAIQIACVMAATSAAIASSSSN"
     gene            complement(5794..6369)
                     /locus_tag="PC465_003597"
     CDS             complement(5794..6369)
                     /locus_tag="PC465_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650865.1"
                     /translation="MKLKEALITCVVCSVCLTPLLVNGETKIDADHCKESIVNIDTIV
                     KSGKSFNSKYNQGMEDYKNSDEYKLKVQKEKLQNQLGIKIKKLVPITFEVSYYTSLNQ
                     ENGYGAITATGDDLEDGFVANNHLSFGTKIIVDGKLKTVMDRGSSKYFSNSNAIDVFV
                     PKWSNESESEYYDRVNNMGRHYKKGYIIVEE"
BASE COUNT         2246 a         1047 c          728 g         2594 t
ORIGIN      
        1 aatataagtt ttctatattt ttaaccaaca gatgttttct tcaaattaat cagatgattt
       61 agtatatctt gaacctttcc agagtccttt aaatatccta atgccccatt tatttgtgat
      121 tttaaatcta tttctacttc catatccaaa tcaacatttc ctttttttat agatatattt
      181 ttaagtgtta ttggataaag ataacttttt tccaaagtaa tcttatttcc attaacctca
      241 aatggaactt ttttattgta gttacttaat attttttcta gcattttatc acttagttta
      301 aattttccaa ttttcacatt ctcaagactt acaactaagt ttccatcctt taaagtaggt
      361 ctcaattcaa gttcatattg actatttacc aaaccaaata ccttatatgg tcctgctacc
      421 tttattttac catttttcat ttcaacaaaa ttattttcaa gttcattaat tccatgcttc
      481 tgcatcaatg tatatattaa atttttaaac tcttcctctg aaacagatat ttttccaacc
      541 attctaagtg gattttttac tacctccata gaatttatat atgagccttt tgataaatat
      601 tcttcatcta tgattttatt attttgtgaa ctaacatcat atctttcttt tggtgtcaag
      661 atatatacaa caattcctgc aagtactaaa acaataacaa ttaaacttaa caaaatcttt
      721 gcaacctttc ccataatcgt ctcctttaca aatctgtcat cagatttaaa ataaatttag
      781 ataactaact tcacataata ttcttaacaa tatacatact ataatacagt cttttaaaaa
      841 ttaattcaac caatctaatg ttttgtaaat aaactgtaaa aacatgtttt tagtataaaa
      901 gttaatattt tgcataatac tcttaattac acctttattt ttttctaatc ttggattaaa
      961 attaatatta tgcaatacag tgtagtgttc tgtattataa tcaaattaaa taggaggtat
     1021 agaatatgtc aaatgaaacg aactcatcta actttataaa gaatattatt ataaacgact
     1081 tagaaacagg aaaacatgac agtatcataa ctcgttttcc acctgagcca aacggatatt
     1141 tacatattgg tcatgcaaaa agtatatgtc ttaattttgg attagctaag gagtttaatg
     1201 gaaaagctaa tttaagattt gatgatacaa acccattaaa agaggatgtt gaatatgtag
     1261 agtccataaa agaagatgta aagtggttag gatttgattg gaacgagtta aattttgcat
     1321 ctaactactt tgatgaaatg tataagagag ctttaatact aataaaaaag ggtaaagctt
     1381 atgtatgtga tttgacacaa gaggaaatga gagaatatcg tggtactcta actgaaccag
     1441 gaaaagaaag tcctcataga aacagaacta ttgaagaaaa ccttgattta tttgaaagaa
     1501 tgaaaaatgg tgaatttaaa gatggtgaaa aaacattaag agccaaaata gatatgtctt
     1561 ctccaaatat aaaccttaga gacccaatta tatatagaat atctcattca acacaccata
     1621 atacaggaga taaatggtgc atatatccta tgtatgcttt tgctcatcca attgaagatg
     1681 caattgaagg aataactcac tctatatgta ctttagagtt tgaagaccaa agacctcttt
     1741 atgattggtt tgttaaagaa tgtgagatgg aaaatatacc tagacaaata gaatttgcta
     1801 gacttaatat aaataatact gtcatgagta aaaggaaatt aaaacaactt gtagatgagg
     1861 gtattgttga tggttgggat gaccctcgtg ttcctacaat atccggaatc agacgtaagg
     1921 gatatactgc agaagcattg cgcaatttct gtagtgaaat aggggtatca aaagttaact
     1981 ctacggtaga tagtcaaatg cttgattatt tcctaagaga aaacttacaa ccaaaggctc
     2041 ctcttactat gggagtttta agacctttaa aacttattat aactaattac ccagaagata
     2101 agattgagat gcttgaaata gagaataatg ctaaagatga atctcaagga aagagattag
     2161 ttcctttctc tagagaattg tatatagaac aagatgattt tatggaagaa cctgttaaga
     2221 aatattttag atttttccca ggaaatgaag tccgtttaaa aggtgcttat tttgtaaaat
     2281 gtactgatgt aattaaggat gaaaatggaa atgtagttga aatacatggt acttatgacc
     2341 ctgaaactaa gagtggctct ggctttacag gacgtaaggt aaaatctaca atacattggg
     2401 ttgatgctaa atcagctata ccatgtgaat ttagattatt tgaaccatta attcttgatg
     2461 atatacctga aaatgaaggt aaacatttct tagaacaaat aaatcctaat tcattggaaa
     2521 tattacaagg ttttgttgaa cctacacaga taaaagatgc taaacctttt gataaattcc
     2581 agtttgttag aaatggattc tttagtatag ataataaata tacaactgat gaaaaatttg
     2641 tatttaatag aatagttcct ctaaaaagtt cttttaaacc aggtaaatag tcttacaatc
     2701 aaaaaatgaa gacttaaaat ataaattact tctactataa ataaacttag ttagaagtaa
     2761 ttttttattt gagtcttcat catttacttt aaatgattaa cttttttcac tacagattcc
     2821 catgacttct attccatctt ttatgcattc tatgttaaga ggaaaatctg gtcctttttc
     2881 tccgtcaata tctgttataa gtgaatcttc acattctata tgcacctttt tagttttaaa
     2941 gtatagtatt tcatttccat tatattgatc taaataatca cctctaagca cacttatcaa
     3001 aactggtatt gattttggta ttggcattcc tttaaaaata attacatcca aatatccatc
     3061 atctatttca gccttatatg ctagatttat atttcctgct gttttgccat taaaaatcaa
     3121 cataagatac atatctccat cataatacat ttcctcagaa gatactttta tcttaaattt
     3181 cctcatatac aatgcttctt ctattccctt tatataataa gaaattcttc caaatgaatt
     3241 ttttaagtct gtgtttatcc tttgtgatac atccgtaaac ataccagcac ttgcaacatt
     3301 tataaagtac ttattattga ctttccctat gtctattttc tttggttttg aatttatgat
     3361 ttcatttata gcttctttta tatcaaatga aatttgaaga gcatttgaaa aatcatttgc
     3421 agttcctgta ggcaaaattc caattggaat ttttatgtct aattctttca ttgcatttac
     3481 tactaaatct acagtaccat caccaccagc tatcaatatg tgttcataag aactatcaac
     3541 ttccttaaat gcattcttta caggttcttt aatagttaat ctatagggta tcaataaata
     3601 atttttttct tgatataatt ctatgatagt gtctaaattt gataatatct ttttttcacc
     3661 tgaattagga ttgtatataa gttttacttt tttcattatt tctccttact cattttattc
     3721 ttttagtatc caaaatcttc atttaaaaaa atcacatgta ttctttctgg tgttaattgt
     3781 ctttttataa gtgtataact acagcatatt cttcctggac ttgaacagtc tatacatata
     3841 ccagtagtct tacatccagt atttgtactt aatcttttac aattggctgg agcagctatt
     3901 gtttttgttc tttttatagc ttcatctaca tctttaacta ttttatttac tcctgctata
     3961 actattactt tatcaggtcc atatatcata gcagcaaccc tattcccatt cccatctaaa
     4021 ttgtaaagtt ctccatcctc tgttatcgca ttagtacttg taaaataagc atctgcagaa
     4081 aatgactttc tatatatttc tttcatttct tctggtttga tatcttttgc atatctatca
     4141 agaaaattat atttttctct tataaaatca atcactcctg tttcaaataa ggtcatagaa
     4201 cctccacatc ctactagaga acctgcttta actatttctt caattttttt aagaagctct
     4261 tctttgttac ttactaaata ccctttcata ttattgtttt ccaaagattt tattgttttt
     4321 tctattcttt tttcattaag ccaatttaaa ttttgatcca ttttaacttc ccccttattt
     4381 ttaatatgta cttaattatt tataaacttt attttcttta taagtttatt ttagtacatc
     4441 taaaaaaaaa tacaatataa aacttaaata gttttacata attttttcca aaataactta
     4501 ctcaatcaaa aaaggaaagt agatgtacta ttctactttc cctatattgt atgtagtatt
     4561 tattgcctaa aatctatata ttaattatat gtttcatatt atataatatc acagttaatt
     4621 aaaatgtaat actatcttct ttttaaacat ataaattgta ttattaaatt taatatatcc
     4681 aacttcaata aatcttatta atttgatgaa gaagatgcta tagctgcact tgttgctgcc
     4741 attacacatg caatttgaat agcaacaaca atatttaaaa atatattatt agttatagag
     4801 cctatattat tctcatttcg tatcaaatct gcataaattg aagctacaat agcagaacta
     4861 atcattactc tattactttt tcctaaagac caatttccaa agcctttttc ttctttaagt
     4921 ttatttgaaa cattttttat ctcttctatt atttcatctt ctctataatc taataatgaa
     4981 attgctccta ttattggata tccataataa ttcattttac aatcattttc tttaaatgct
     5041 tttttaagtt caatagtctt tttacattta agcatagttc tatcatcact aaataaaaga
     5101 atttgggata atgcttgtaa atcatttcct ttataaaaac cattttcatt tagaaattca
     5161 taacattttt ctatgtattc taaatcttca tctaaatttt ttgaatgaat tgcaataagt
     5221 gctatattac aatagtcatc actagaagtt agaaatggat gttttttcct catataatca
     5281 tatattattt tcatttttga tatacatgta agataatcca ttttctctct attttcataa
     5341 actattgatg ctgtaagtgg taaatatgta tcgccccaaa acttttcact tttaagttct
     5401 ttgtatatat ctaaaatcat cttaaaacta ctttctggat ttgattcaaa cgaaagtagt
     5461 gttgccatat aaaacatatt atatcctcta aaattagaga ataatccagt atttttttta
     5521 ataagctcta ttcgttcttc cactaatcta ggacttattc tcttgttctt aagggtaaat
     5581 gcaagtgcac aactatgttg tatcaatccc atttgccaag aacctttaac ttcatttaat
     5641 gctttgtaat tttctattaa taagtttact tttccattta taaacgattg ttccatattg
     5701 ccctcctagt aatatatctc attgtactaa tagttttata tttattatat atatattaaa
     5761 tactacaatc aatacatatt acttcaaaga acatcattct tcaacaataa tgtagccttt
     5821 tttgtaatgt cttcccatat tattgactct atcatagtac tctgattcac tttcattact
     5881 ccatttgggc acaaatacat ctattgcatt agaattacta aaatacttac tagaccccct
     5941 atccataaca gtttttaatt ttccatctac aataatctta gttccaaaac ttaagtgatt
     6001 gtttgctaca aaaccatctt ctaaatcatc tcctgtagca gttatcgctc catatccatt
     6061 ttcttgatta agacttgtgt aataactaac ttcaaaagtt ataggtacta acttctttat
     6121 tttaatacct aactgatttt gtagtttctc cttttgtact ttcaacttat actcatcact
     6181 atttttataa tcttccatac cttgattata cttggaatta aagcttttac ctgactttac
     6241 tatagtatct atatttacta tagattcttt acaatgatct gcatctattt ttgtttctcc
     6301 atttaccaat aatggagtta aacatacact acatacaaca catgtaatca atgcttcttt
     6361 aagcttcata aattcccccc ttattatttt gatatattag catatttaat attatatgtc
     6421 tacatttaga tttaaatacc acacccattt gctttaagaa gttgtcttat atttaattca
     6481 ccttaaacac ttataaatcc tctatcttag aatcatatag aataaagctt ttatctttaa
     6541 atatttttta ttaatctttt aaaatctaaa actactttat ctaattttct cttttttaga
     6601 atttaagaat taaaa
//
LOCUS       DAMJXI010000125         6408 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.132, whole genome shotgun sequence.
ACCESSION   DAMJXI010000125 DAMJXI010000000
VERSION     DAMJXI010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6408
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.132"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            293..1237
                     /locus_tag="PC465_003598"
     CDS             293..1237
                     /locus_tag="PC465_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HDF2650866.1"
                     /translation="MKFLRIEDEVIYSKKRYKLKREIDKLFLDEEYFQIEPQLFEEYD
                     EFTTINNKIPEESMVKVVNGKVMVLRADITTSIIKSLVPRWEDGLKLKLFYNSSIYKN
                     KNTVGIKEIRQIGCEYLGEASVEADREVVKLALKILEKYNNNFILEVGSSKYIHGLLE
                     ELNLNKNCENQIKNLLYTKNTHELKVYIEELKIKREVKELLSNILSLQGNLYNVIEKS
                     NKFYCNNKMKQALEELKQVNNLIEECNFLDKARFDLSMITMLDYYEGIMFRGYYPNSY
                     KEILSGGRYDSLTKEYGKEIPAIGFTLSVDELMKYVYK"
     gene            1259..1885
                     /locus_tag="PC465_003599"
     CDS             1259..1885
                     /locus_tag="PC465_003599"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HDF2650867.1"
                     /translation="MDYLTIALAKGRIEGESFKKFKKMGLGDSIDTDTRKLIFKDEEN
                     KIIYIHVKPSDVVTYVEKGVADLGIAGKDTILENETDVYEIYDLGFGKCKFAVAGLKG
                     DSIYREDEYLKVATKYPNIAKKYFKEKGQKIEIIKLNGSVELAPIVGLSDVIVDIVET
                     GNTLKANGLEILEDICNISARIISNRASYRFKYEQIQNIIRLFEELDN"
     gene            1919..2968
                     /gene="hisC"
                     /locus_tag="PC465_003600"
     CDS             1919..2968
                     /gene="hisC"
                     /locus_tag="PC465_003600"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HDF2650868.1"
                     /translation="MREKESIRELRGYEPNHVNCKVKLDANEGSKRLFKYLIKEISDS
                     DIDLNLYPEDSYSDLKESIIDYINISGVNKKNLLVGNGSSEIIDLIIHTFVDKDEVIL
                     SFSPSFSMYSIYSQINGSKFIGVESDENLVINIDNVIEKVKENNPKIVIVCNPNNPTG
                     TILKREEIIKLLDSTNSLVVLDEAYMDFGEESMLSDVFKYDNLIVLRTLSKAFGLAGI
                     RTGYMLSNSSLINSVEKVRPPYNLNSLSDFIATRALRNKDVVKAYIKEVKEEREVLYE
                     EMIGMGIKAYKSQANFILFYSEIENLSQKLIDRGVLIRKFGGKLENYYRVTIGDKEEN
                     SMFVGAIRDILKKEK"
     gene            2971..3549
                     /gene="hisB"
                     /locus_tag="PC465_003601"
     CDS             2971..3549
                     /gene="hisB"
                     /locus_tag="PC465_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HDF2650869.1"
                     /translation="MRIWKVERNTLETQILVELNIDGSGKAEIDTGIGFLDHMLTLMS
                     FHGKFDLKVICKGDTYVDDHHSVEDIGIAIGEAFKNALGDKKGIRRYSNIYIPMDESL
                     SMVAIDISNRPYLVFNAKFDTQMIGSMSTQCFKEFFRAFVNESRVTLHINLLYGENDH
                     HKIESIFKAFARALKEGSEIVSNEIASSKGVL"
     gene            3551..4156
                     /gene="hisH"
                     /locus_tag="PC465_003602"
     CDS             3551..4156
                     /gene="hisH"
                     /locus_tag="PC465_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HDF2650870.1"
                     /translation="MNIIVDYGLGNIDSVSRGFRKAGIETKISSDIDEIKQADSLILP
                     GVGAFRDSISALDKLGLIPIIKEHVSKGKFMIGICLGMQLLYEKSYEYGEYEGLGLIK
                     GSIDKLDISLKVPHMGWNNLKFNKANDDILKYINEDDYVYFVHSYYANSSNEELIAFS
                     EYEKKIPAIVRKGNVYGIQFHPEKSGEVGLNILRAYGEMIK"
     gene            4153..4875
                     /gene="hisA"
                     /locus_tag="PC465_003603"
     CDS             4153..4875
                     /gene="hisA"
                     /locus_tag="PC465_003603"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HDF2650871.1"
                     /translation="MIIFPAIDIKDNKCVRLTQGEFDKVNVYYDNPLEVAYKWKNEGA
                     EYIHIVDLNGARSEFGVNTKIIEDIANNIDIPIQVGGGVRDKEKVKSLINAGVTRVIL
                     GSIAIENLNLVEELVNEYKEKIVVSIDAKDGKVAVRGWEVVSNVDSLTLCKQLEKIGV
                     QTIVYTDISKDGMLQGPNFDIYERIAKETSLNVIASGGVTSIEDVKRLKAMNLYGAII
                     GKALYDKKIDFKEAQQLCLLGE"
     gene            4857..5615
                     /gene="hisF"
                     /locus_tag="PC465_003604"
     CDS             4857..5615
                     /gene="hisF"
                     /locus_tag="PC465_003604"
                     /EC_number="4.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HDF2650872.1"
                     /translation="MLTRRIIPCLDVRNGRVVKGKKFKDIVDVDSPEVLGKFYSDCGA
                     DELVFYDITASNEERKTSLEFVTKVAENINIPFCVGGGVNKLEDFTDILRKGADKVSI
                     NSSAVKNPELIREASLKFGAQCVVLSIDAKKNEEGSWSVYVKGGREKTNLDAIEWAVK
                     GVELGAGEIVVNSMDEDGMKNGYDIELLSKITSLVNVPVIASGGAGKKEDFYEAVNKS
                     NVDGILAASVFHFGEIKINDLKKYLKDMGVEVRL"
     gene            5643..6311
                     /locus_tag="PC465_003605"
     CDS             5643..6311
                     /locus_tag="PC465_003605"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HDF2650873.1"
                     /translation="MDNKCNNVYSDEVEKFIRSIKFDDKGLVPVVVQEVVSKDVLMLA
                     CMNKDAIKKTLKDKVACYFSRSRQELWVKGETSGNTQKVVKMSYDCDVDTILLFVEQT
                     GVACHTGNYSCFYRDLFDDSSKMELEVQTNILKELYDLINERKNNPVEGSYTNYLFEK
                     GIDKILKKVGEESSEVIIASKNTDKSELIYEISDLVYHTLVLMIEKGVEIDEIKKELL
                     KRRK"
BASE COUNT         2617 a          537 c         1262 g         1992 t
ORIGIN      
        1 gtaaatttag aatattaata aaaattattt gggaggaaat tatcatggtg agattaaata
       61 tagtaaaatt aaatacaaaa ttaaatcatc accatcatca tagattaaag ggattgtaat
      121 atgaaattaa ttcatagaca caagccctgt ttttagtgta attggtcttg tatctatgat
      181 gggaagtaat tttaagagaa aattatagcc atataggtat aaagcctata tggctttttt
      241 attgttttaa atttgcaaat ataagagtaa atttaatgaa gagggtgaga atgtgaaatt
      301 tttgaggatt gaagatgagg ttatttattc taaaaaaaga tataaattaa aaagggaaat
      361 agataaactt tttttggatg aagaatattt tcaaatagaa ccacaattat ttgaagaata
      421 tgatgaattt acaactataa ataataaaat tccagaagaa tctatggtaa aggttgtaaa
      481 tggaaaagta atggtactta gagctgatat aactacaagt ataataaaaa gccttgtacc
      541 aagatgggaa gatggtttaa agcttaagct tttttataat tcatcaatat ataaaaataa
      601 aaatacagtt ggaataaaag agataagaca aataggttgt gagtatctag gagaagcctc
      661 tgtagaagca gatagagaag tagtgaaatt agctcttaag atacttgaaa aatacaataa
      721 taattttatt ctagaggttg ggagtagcaa gtatattcat ggtttgttag aagaattaaa
      781 tttaaataag aattgtgaaa atcaaattaa aaatttacta tatacgaaga acactcatga
      841 actaaaagta tatattgaag aattaaaaat taagcgtgaa gtaaaagagt tattatcaaa
      901 tattttaagt ttacaaggga atttatataa tgttattgaa aaatcaaaca agttctattg
      961 taataataag atgaagcaag ctcttgaaga attaaagcaa gtaaataatt taattgagga
     1021 atgtaatttt ttagataagg ctagatttga tttatcaatg attactatgc ttgactatta
     1081 tgaaggaatt atgtttagag gatactaccc aaactcatat aaagaaattc ttagtggcgg
     1141 aagatatgat tctttaacta aagagtatgg aaaagaaatt ccagccattg gatttacact
     1201 aagtgttgat gagttaatga agtatgtata taagtaaagt ttataaggag ggattgtttt
     1261 ggattatttg actatagcac tagcaaaagg acgaattgaa ggggaatcat ttaaaaaatt
     1321 taaaaaaatg ggtctaggag atagtataga cacagatacg agaaaactaa tttttaaaga
     1381 tgaagaaaat aaaattatat atatacatgt aaagccatca gatgtagtta catatgttga
     1441 aaaaggagtc gctgacctcg gtatagcagg taaagatact attttagaaa atgagacaga
     1501 tgtatatgaa atatatgatt taggttttgg aaagtgtaaa tttgctgtag caggattaaa
     1561 gggagatagc atatatagag aagatgaata tttaaaagtg gcaacaaagt atcccaatat
     1621 agcaaaaaag tattttaaag agaaaggtca aaaaattgaa ataataaaat taaatggttc
     1681 tgtagaacta gctccaatag tagggttgtc agatgtaatt gtagatatag ttgagactgg
     1741 caatacactt aaagcaaatg gtcttgaaat attagaagac atatgtaata taagtgctag
     1801 aattatatca aatagagcta gctatagatt taaatatgaa caaattcaga atataattcg
     1861 tttatttgaa gaacttgata attaaaatat aattgagctt tataaggagg gatttaagtt
     1921 gagagaaaaa gaaagcataa gagagttaag gggatatgaa ccaaatcacg taaactgtaa
     1981 agtaaaactt gatgcaaatg aaggaagtaa gaggttgttt aaatacctta ttaaagaaat
     2041 ttcagatagt gatatagatt taaatttata tcctgaagat tcttatagtg atttgaaaga
     2101 atctataata gattacataa atatttctgg agtaaataag aaaaatcttc tagtaggaaa
     2161 cggttcaagt gaaataattg atttaataat acatactttt gtagataaag atgaagtaat
     2221 attgagtttc tctccaagtt ttagtatgta ttctatatat agtcagataa atgggtctaa
     2281 atttataggt gttgaaagtg atgaaaattt agttataaat atagataatg tgattgaaaa
     2341 agtaaaggag aataatccta aaatagtaat tgtatgtaat cctaataatc caacgggaac
     2401 aatattaaag agggaagaga taataaagct tttagattca actaatagtc tagtggtttt
     2461 agatgaagca tatatggatt ttggagaaga aagcatgtta agtgatgttt ttaagtatga
     2521 taatctaata gttcttagaa ctttatcaaa ggcatttgga ttggctggaa taagaacagg
     2581 atatatgtta tctaatagta gtttaataaa ttctgttgag aaagtaagac ctccatataa
     2641 tttaaattca ttatcagact ttattgctac aagagcactt agaaataaag atgtggtaaa
     2701 ggcttatata aaggaagtaa aagaggaaag agaagtttta tatgaagaaa tgattggtat
     2761 gggaattaaa gcatacaaat cacaagcaaa ttttatatta ttttattctg aaatcgaaaa
     2821 tttatcacaa aaacttattg atagaggtgt tttaataaga aaatttggtg gaaagttaga
     2881 aaattattac agagttacaa ttggtgataa agaagaaaat tctatgtttg ttggagctat
     2941 aagagatatt ttgaaaaagg agaaataggt atgagaattt ggaaggtaga aagaaatact
     3001 cttgaaacac agattttagt agaattaaat attgatggtt ctggtaaagc tgaaatagat
     3061 actggaatag gatttttaga ccatatgctt accttaatgt catttcatgg caagttcgat
     3121 ttaaaagtga tttgtaaggg tgatacatat gtagatgacc accatagtgt agaagatata
     3181 ggtatagcta taggtgaagc atttaaaaat gcactaggtg acaaaaaagg aatacgaaga
     3241 tattctaata tctatatacc tatggatgaa tctctatcaa tggtagcaat agatataagc
     3301 aatagacctt atcttgtatt taatgctaaa tttgataccc aaatgattgg tagtatgagt
     3361 actcaatgct ttaaagaatt ttttagagct tttgtaaatg aatcgagagt aacattacat
     3421 atcaatctct tatatgggga aaatgaccat cataagatag aaagtatttt taaagcattt
     3481 gcaagagctt taaaagaggg tagtgaaata gtttctaatg agatagcatc ttcaaagggg
     3541 gttttgtaga atgaatataa tagtagacta tggtcttgga aatatagatt ctgtgtctag
     3601 gggttttaga aaagctggaa tagaaactaa aatttctagt gatatagatg aaataaaaca
     3661 ggcagattca cttatacttc caggtgttgg agcttttaga gattctataa gtgccttaga
     3721 taaactagga ttgataccaa taataaagga gcatgtttct aagggtaaat ttatgatagg
     3781 tatatgtcta ggaatgcaat tactttatga aaaaagttat gagtatggag aatatgaagg
     3841 attaggactt ataaaaggaa gtattgataa actggatata agtttaaaag tgccacatat
     3901 gggatggaat aatctaaaat ttaataaggc aaatgatgat atacttaaat atataaatga
     3961 agatgattat gtatacttcg ttcactcata ttatgcaaat tcatcaaatg aagaactaat
     4021 tgcattttca gaatatgaaa agaaaatccc tgctattgtt agaaaaggca atgtatatgg
     4081 tatacaattt catcctgaaa aaagtggaga agtagggtta aatatattaa gagcatatgg
     4141 ggagatgata aaatgataat atttccagca atagatataa aagataataa gtgtgtaaga
     4201 ctcacacaag gagaatttga caaagtaaat gtatattatg ataatccatt agaagtagca
     4261 tataaatgga aaaatgaagg agcagaatat atacatatag tagatttaaa tggtgctaga
     4321 agtgaatttg gtgtaaatac aaaaataatt gaggacatag caaacaatat agatatacct
     4381 attcaagttg gcggtggagt tagggataag gaaaaagtca aaagtttaat aaatgctggt
     4441 gttactagag taatattagg cagtatagcg attgaaaatt tgaatttagt tgaagaattg
     4501 gtcaatgaat ataaagagaa aattgtagtt tctatagatg ctaaagatgg aaaagtagca
     4561 gttaggggat gggaagttgt aagcaatgta gactcattaa cattatgtaa acaacttgaa
     4621 aagataggtg tacaaactat tgtttataca gatatatcaa aagatgggat gttgcaaggt
     4681 ccaaattttg acatatatga aagaatagca aaggaaacat cactaaatgt tattgcttct
     4741 ggaggtgtaa cttctataga agacgtaaaa agactaaaag ctatgaactt atatggtgca
     4801 ataataggta aagcgcttta tgataaaaag atagacttta aggaggcaca acaattatgc
     4861 ttactaggag aataatacct tgtctagatg tgagaaatgg aagagttgta aaggggaaaa
     4921 aatttaaaga tatagtagat gttgatagtc cagaagtact tggaaaattt tatagtgatt
     4981 gtggtgcaga tgaacttgta ttctatgata taactgcatc aaatgaagag agaaagacat
     5041 ctttagaatt tgtgacaaaa gttgcagaaa atataaatat accattttgt gttggtggag
     5101 gagtaaataa attagaagat ttcactgata ttttaagaaa aggtgctgat aaagtttcta
     5161 taaattcatc agcagtcaaa aatcctgaat taataaggga agcttcatta aaatttggag
     5221 cacaatgtgt tgttttatcg atagatgcaa agaaaaatga agagggttca tggagcgtat
     5281 acgtaaaagg tggaagagaa aaaactaatc tggatgcaat tgaatgggct gttaaaggtg
     5341 tagaacttgg agcaggagaa atcgttgtaa atagtatgga tgaagatgga atgaaaaatg
     5401 gatatgatat agaattatta tcaaagataa cttctttagt aaatgtacct gtcatagcat
     5461 ctggaggcgc tggaaaaaag gaagattttt atgaggcggt taataaatcc aatgtagatg
     5521 gaattttagc agcatctgtt tttcattttg gcgagataaa aataaacgat ttaaagaaat
     5581 atttaaaaga catgggtgta gaagtaagat tataagttaa atactaaaag gagattagaa
     5641 atatggataa taagtgtaac aatgtataca gtgatgaagt agagaaattt ataagaagta
     5701 taaagtttga tgataaaggg ttagtccctg ttgttgttca agaggtagtt agcaaagatg
     5761 tactgatgtt agcatgtatg aataaagatg ctataaagaa aaccttaaaa gataaagtag
     5821 cttgctattt tagtagaagt agacaagaac tttgggttaa aggtgagaca tctggtaata
     5881 ctcaaaaagt agttaagatg tcttatgatt gtgatgtaga tactatacta ctttttgttg
     5941 aacaaactgg tgtagcttgt catacaggca attattcttg tttttacaga gacttgtttg
     6001 atgatagttc aaaaatggag cttgaagtac aaacaaatat attgaaagaa ttatatgatt
     6061 taatcaatga aagaaaaaat aatccagttg aaggttctta tactaattat ctttttgaaa
     6121 aaggaataga taagattctt aaaaaagtag gtgaagagag tagtgaggta attatagcat
     6181 caaaaaatac tgataaaagt gaacttattt acgaaattag cgatttagta tatcatacat
     6241 tggttttaat gatagaaaaa ggtgttgaaa ttgatgaaat aaaaaaagaa ttacttaaaa
     6301 gaagaaaata gaataagata gattaatggg taataagaaa atataccact tttaataaaa
     6361 agtggtatat tttttatttt atattttgat ttatagaata atatttaa
//
LOCUS       DAMJXI010000126         6383 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.133, whole genome shotgun sequence.
ACCESSION   DAMJXI010000126 DAMJXI010000000
VERSION     DAMJXI010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6383
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.133"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            153..1439
                     /locus_tag="PC465_003606"
     CDS             153..1439
                     /locus_tag="PC465_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HDF2650874.1"
                     /translation="MRLELGKIFIKDIQFGDVTEVKDGVLFINKQEMLQEIGGDEHIK
                     SIDIELARPGESVRITPVKDVIEPRVKVEGNGGIFPGIMSKVDTVGEGKTHALKGVAV
                     VTTGKIVGFQEGIIDMTGEGAKYTPFSKLNNVVVIAEPIDGLKQYAHEKAVRMIGFKA
                     AMYLGEVARNLTPDEVSVYETKPLLESIKEYPELPKVGYVYMLQTQGLLHDTYVYGVD
                     AKQIVPTLLYPTELMDGAIVSGNCVSACDKNPSYVHINNGVVEDLYARHGKDINFVGV
                     IITNENVYLADKERSSNWTSKLCKYLGLDAVIVSQEGFGNPDTDLIMNCKKIEMQGVK
                     TVIVTDEYAGRDGGSQSLADADVRADAVVTGGNANQVVVLPKLDKVIGHLEVVDVIAG
                     GSDGSLRADGTIEVEIQAITGATNETGFGHLTAKGY"
     gene            1551..2024
                     /locus_tag="PC465_003607"
     CDS             1551..2024
                     /locus_tag="PC465_003607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:1683..1685,aa:Sec)
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     selenoprotein A"
                     /protein_id="HDF2650875.1"
                     /translation="MSLLSNKKVLIIGDRDGIPGPAIEECVKTVEGAEVVFSSTECFV
                     UTAAGAMDLENQNRVKDAADKFGAENVVILLGAAEAEAAGLAAETVTAGDPTFAGPLA
                     GVALGLSVYHVVEEPIKSLFDESVYEDQISMMEMVLEVEEIEEEMSGIREEFCKF"
     gene            2056..3366
                     /gene="grdB"
                     /locus_tag="PC465_003608"
     CDS             2056..3366
                     /gene="grdB"
                     /locus_tag="PC465_003608"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:3103..3105,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HDF2650876.1"
                     /translation="MGKLKAVHYINQFFAGIGGEEKADTKPHVAETLPPISLQLDKLL
                     GEDIEIVGTVVCGDSYFNENIDSASEEVLSMVKGFEPQLFIAGPAFNAGRYGVAAGTI
                     TKVVKDALNIPALTGMYVENPGADMFKKDVYVVETSDSAAGMRKALPKIAKLAVKLAN
                     GEEIGTPKDEGYIARGIRVNYFHEDRGSKRAVDMLVKKIKGEPFETEYPMPNFDRVDP
                     SKAVKDLSKCKIALVTSGGIVPKGNPDRIESSSASKYGTYSIAGVMDLTEETYETAHG
                     GYDPVYANLDADRVLPVDVLRDLEKEGVIGKLHETFYTTVGNGTSVANSKKYASEIGA
                     ALVADGVDAVILTSTUGTCTRCGATMVKEIEKTGLPVVHMCTVVPISLTVGANRIVPT
                     IAIPHPLGNPALDPTEEKALRRGLVEKALNALTTEVDGQTVFEK"
     gene            3623..5155
                     /locus_tag="PC465_003609"
     CDS             3623..5155
                     /locus_tag="PC465_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014520415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III family protein"
                     /protein_id="HDF2650877.1"
                     /translation="MTYPVLKGAGYVLIHTPDMIVQNGSTCTVERATNPDSEFLKEVS
                     NHIRSYEDVVNYMPNQVYIGNRRPEELRDLPMPWCEQKIEGTRNGKFGEIMPQDEFIA
                     LMQISDAFDLVKLSQEFIDEVKPKIENNYPEIAPFVGKLKGDDIEEGKELVATHIAEG
                     LYHDGKFVGYVKRAHDVDVNLNAHTMFENLVVKASGVLSAIQMLRHSKIDPAEIDYVI
                     ECSEEACGDINQRGGGNFAKSIAEIAGLQNATGSDTRGFCAAPTHALIQAAALVKAGI
                     HKNVMVVAGGASAKLGMNAKDHVKKGLPVLEDVVGGFAVLVSENDGVNPVIRTDLTGK
                     HTVGTGSSPQAVMTALITSGLDRANLKITDVDVYSVEMQNPDITKPAGAGDVPEANYK
                     MIGALAVKRGDLEKKELKDFVSNKGLPGWAPTQGHIPSGAPYIGFLIDDLTTGNRNRA
                     MIVGKGSLFLGRMTNLFDGVSFIAERNTGVTEETSGISKDEIKKIIAESMKKLALDML
                     EE"
     gene            5166..6311
                     /locus_tag="PC465_003610"
     CDS             5166..6311
                     /locus_tag="PC465_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine reductase"
                     /protein_id="HDF2650878.1"
                     /translation="MSKKVIADVFLEVANAIESGEFGKKVKIGVTTLGSEHGVENMVN
                     GAQLAKSNLFDIVLIGPKVETDLEVVEVNDEKEMHAKMEELLDSGYIDACVTMHYNFP
                     IGVSTVGRVITPAKGKEMILATTTGTSATNRIEAMVRNAIYGIATAKSMGNKCPKVGI
                     LNVDGARQVEKCLKELKDNGYDMEFADSIRADGGCVMRGNDLLVGAPDVMVTDTLSGN
                     IFMKVFSSYTTGGDYEAQGFGYGPGVGEDYDRKVLIVSRASGSPVVANALKYAYDVVK
                     GDISNVARNEFAKVKKAKFDDIISSLTKKEVKAEKVEVKMPDKEIVTRQIAGVDIMDL
                     EDAVSELWKNGIYAESGMGCTGPIVLVNEAKGDLAVETLVKAGYTAK"
BASE COUNT         2450 a          768 c         1330 g         1835 t
ORIGIN      
        1 ttacaataaa tattttttag taataaaata aagatttaag gcataaaaac acaataatat
       61 atctttaaaa aaataagata aattgtaaaa tgatataatt ttgagaaaaa ctcaaatgca
      121 tatacacaaa ttaaataaca ggaggtgcaa gtatgcgtct tgaattaggg aaaatcttta
      181 taaaagatat tcaatttggt gatgtaacag aagtaaaaga tggagtatta ttcatcaata
      241 agcaagagat gctacaagaa attggtggag atgagcatat taaatctata gatatagaat
      301 tagctcgtcc aggtgaaagc gtaagaataa cacctgtaaa agatgttatt gagccaagag
      361 taaaagttga aggtaatggg ggaatcttcc ctggtatcat gtctaaagtt gacactgtag
      421 gagaaggaaa aactcatgct ttaaaaggtg tagctgttgt aactactgga aaaatagtag
      481 gtttccaaga aggtataata gacatgactg gagaaggagc taagtacact ccattttcta
      541 aattaaataa tgtagtagta atagctgaac ctattgatgg tttaaaacaa tacgctcatg
      601 aaaaagctgt tagaatgata ggattcaaag cagcaatgta cttaggagaa gtagcaagaa
      661 atcttactcc agatgaagtt tcagtatatg aaactaaacc tcttcttgaa tcaataaaag
      721 aatatccaga gcttccaaaa gtaggatatg tttacatgct tcagactcaa ggtttattac
      781 atgatactta tgtatatgga gtagatgcaa aacaaatagt accaacttta ttatatccaa
      841 cagaattaat ggacggagca attgtaagtg gtaactgtgt ttctgcatgt gacaaaaacc
      901 caagttatgt tcatataaac aatggggttg ttgaagactt atatgcaaga catggtaaag
      961 atataaactt tgtaggtgta attataacta atgaaaatgt ttatctagca gataaagaaa
     1021 gatcttcaaa ctggacttct aaattatgta aatatttagg attagatgca gttatagttt
     1081 cacaagaagg ttttggaaat cctgatactg accttataat gaactgtaag aagatagaaa
     1141 tgcaaggtgt taaaacagtt atagttacag atgaatatgc tggacgtgat ggaggttctc
     1201 aatcacttgc agatgcagat gtaagagctg atgctgttgt aacaggtgga aatgccaacc
     1261 aagttgtagt tcttcctaag ttagataaag ttattggaca tttagaagta gtagatgtaa
     1321 tagctggtgg ttctgatgga agtttaagag ctgatggaac tattgaagtt gaaatccaag
     1381 ctataacagg tgcaactaat gaaacaggat ttggtcattt aactgctaaa ggatattaag
     1441 aagtatttta ttaaacgatt gagtaatgtt aataaaacat attatagata attataataa
     1501 gtgttataga tatataaaaa tatattagaa atataataag gaggattatt atgagtttac
     1561 ttagtaataa aaaggttctt ataataggtg accgtgatgg tataccagga cctgcgatag
     1621 aagaatgtgt aaaaacagta gaaggagcag aggttgtttt ctcatctaca gaatgctttg
     1681 tctgaacagc tgctggggct atggacttag aaaatcaaaa cagagttaaa gatgctgctg
     1741 ataaattcgg agctgaaaat gttgtgattt tactaggtgc tgctgaagcc gaagctgcag
     1801 gtcttgcagc cgaaacagta actgctggag atccaacttt cgctggacca cttgctggag
     1861 ttgccttagg attaagtgtt taccacgttg ttgaggaacc aataaaatca ttatttgatg
     1921 aaagtgtata tgaggaccaa ataagtatga tggaaatggt tttagaagtt gaagaaatag
     1981 aagaagaaat gtctggtata agagaagaat tttgtaaatt ttaatgccta aaagcaaaag
     2041 gggtgaaact aagagatggg aaaactaaaa gcagtacatt atattaatca gttctttgct
     2101 ggtataggtg gagaagaaaa agctgatact aagccacatg tggcagaaac tttacctcca
     2161 ataagtttac aacttgataa attattaggt gaagatattg aaatagttgg aacagtagtt
     2221 tgtggagata gctatttcaa tgaaaatata gatagtgcaa gtgaagaagt tttatcaatg
     2281 gtaaaaggtt ttgaaccaca acttttcata gctggtcctg catttaatgc tggtagatat
     2341 ggggttgctg ctggaacaat aactaaagtt gtaaaagatg ctttgaatat accagcttta
     2401 acaggtatgt atgttgaaaa tccaggagca gatatgttca aaaaggatgt ttatgtagta
     2461 gaaacttctg attctgcagc aggtatgaga aaggcacttc ctaagatagc taaacttgca
     2521 gtaaaacttg ctaatggaga agaaattgga actcctaaag atgaaggata catagctaga
     2581 ggaataagag ttaactactt ccatgaagac agaggttcta agagagctgt tgacatgtta
     2641 gttaagaaaa taaaaggtga accatttgaa actgaatacc caatgccaaa ctttgataga
     2701 gttgacccaa gtaaagctgt aaaagattta tcaaaatgta aaatagcttt agttacttct
     2761 ggtggtatag ttccaaaagg aaatccagat agaatagagt cttcttcagc ttctaaatat
     2821 ggaacttatt ctatagcagg agttatggat ttaacagaag agacttatga aactgcacat
     2881 ggtggatatg acccagtgta tgcaaattta gatgcagata gagtattacc tgttgatgtt
     2941 cttagagatt tagaaaaaga aggtgtaatt ggaaaattac atgagacttt ctatacaact
     3001 gtaggtaatg gtacatctgt tgcaaactct aaaaaatatg cttctgaaat tggagcagca
     3061 ttagtggctg atggtgtaga tgcagtaata ttaacttcta catgaggtac ttgtactcgt
     3121 tgcggtgcaa cgatggtaaa agaaatagaa aaaactggac ttccagtagt tcatatgtgt
     3181 acagtagtac ctatttcatt aacagtaggg gctaatagaa tagttccaac tatagcaata
     3241 cctcatccac ttggaaatcc agcgcttgac cctacagaag aaaaagccct aagaagaggc
     3301 cttgtagaaa aagcattaaa tgctttaact acagaagtag atggtcaaac agtatttgaa
     3361 aaataaaaat aacacacaca tatattatat agataaaaat ataaacacac actaaaaata
     3421 aaaaataact atacacaaaa aaaataatat agatttcatg aatggataaa ttggagttat
     3481 tcattcatga aatcttaaaa aatgccaaaa tacataaaca ataatagaat caaatataca
     3541 ataaaataca atgattagag cttttaataa gtttaataag attaaaaaat aagtgttcat
     3601 aaaatttatg gaggtgcaca aaatgactta tccagtttta aaaggggcag gctatgtact
     3661 tattcatact ccagatatga tagtgcaaaa tggaagtact tgtacagttg aaagagcaac
     3721 aaatccagat tcagaatttt taaaagaagt aagtaatcat ataagaagtt atgaagatgt
     3781 agttaactac atgccaaatc aagtttatat aggaaataga agaccagaag aattaagaga
     3841 tttaccaatg ccatggtgtg aacaaaagat tgagggaact agaaatggta agtttggaga
     3901 aataatgcct caagatgagt tcatagcttt aatgcaaata agtgatgcat ttgatttagt
     3961 aaaattatca caagaattta ttgatgaagt aaagccaaaa atcgaaaata actaccctga
     4021 aattgcacca tttgtaggta aattaaaggg tgatgatata gaagaaggta aagaattagt
     4081 agcaacacac atagctgaag gattatacca tgatggaaaa tttgttggtt atgtaaaaag
     4141 agcacatgat gtagatgtta acttaaatgc ccatacaatg tttgaaaatc tagtagtaaa
     4201 agcatctgga gttttatctg ctattcaaat gctaagacat agcaaaatag accctgctga
     4261 aatagattat gttattgagt gttcagaaga agcttgtgga gatataaacc aaagaggtgg
     4321 aggaaacttt gctaaatcaa tagctgagat agcaggactt caaaatgcaa ctggttctga
     4381 cacaagagga ttttgtgcag caccaactca tgcattaatt caagcagcag ctttagtaaa
     4441 agctggtata cataaaaatg taatggtagt agcaggtgga gcaagtgcta aacttggaat
     4501 gaatgctaaa gaccatgtta aaaaaggtct tcctgtactt gaagatgttg ttggaggatt
     4561 tgcagtactt gtatctgaaa atgatggtgt aaatccagtt ataagaactg atttaacagg
     4621 taagcatact gttggaactg gttcttcacc acaagcagtt atgacagcac ttataacttc
     4681 aggtcttgat agagctaatt taaaaataac agatgttgat gtgtattcag ttgaaatgca
     4741 aaacccagat ataactaagc cagcaggagc aggagatgtt ccagaagcaa actacaaaat
     4801 gataggggca cttgctgtta aacgtggaga cttagaaaag aaagaattga aagattttgt
     4861 ttctaacaaa ggattaccag gatgggcacc aactcaagga catataccat caggagctcc
     4921 ttatatagga tttttaatag atgatttaac tacaggaaat agaaatagag ctatgatagt
     4981 tggaaaaggt agtttattct taggaagaat gactaactta tttgatggag tatcttttat
     5041 agctgaaaga aatacaggtg ttactgaaga gacttcagga atatctaagg atgaaattaa
     5101 gaagataata gctgaatcta tgaaaaaact agcattagat atgttagaag aataggggtg
     5161 aggatatgtc aaaaaaagta atcgcagatg tattcttaga agtagctaat gcaatagaaa
     5221 gcggcgaatt tggcaaaaaa gtaaaaattg gtgttactac acttggaagt gaacatggtg
     5281 tagaaaacat ggttaatggt gcacaattag caaaatctaa tttatttgat attgtgctta
     5341 ttggaccaaa agtggaaact gaccttgaag tagttgaagt taatgatgaa aaagaaatgc
     5401 atgcaaaaat ggaagaatta ttagattcag gatatattga tgcttgtgtt actatgcatt
     5461 ataattttcc aataggtgta tctacagtag gtagagtaat aactccagca aaaggaaaag
     5521 aaatgatact tgcaacaaca acaggaacaa gtgctactaa tagaatagag gcaatggtaa
     5581 gaaatgccat ttatggtatt gctacagcta aatcaatggg taacaaatgc ccaaaagttg
     5641 gaatacttaa tgttgatgga gcaagacaag ttgagaagtg cttaaaagaa ttaaaagata
     5701 atggatatga catggagttt gcggattcaa ttagagcaga tggtggatgt gtaatgagag
     5761 gtaatgattt acttgtaggt gcacctgatg ttatggttac tgatacatta tctggaaata
     5821 tatttatgaa agtattttct tcatatacta caggtggaga ttatgaagct caaggctttg
     5881 gatacggacc tggagttgga gaagactatg atagaaaggt acttatagta tcaagagcat
     5941 caggttctcc ggtagtagca aatgctttaa aatacgctta tgatgttgta aagggagata
     6001 taagtaatgt tgcaagaaat gaatttgcaa aggttaaaaa agcaaaattt gatgacatta
     6061 tatcctctct tactaaaaaa gaagttaaag ctgaaaaagt agaagttaaa atgccagata
     6121 aggaaattgt tactcgtcaa atagctggtg ttgatataat ggatttagaa gatgcagtat
     6181 ctgagttatg gaaaaacgga atctatgctg aaagtggtat gggttgtaca ggtccaatag
     6241 ttttagtaaa tgaagctaaa ggagacttag cagttgaaac tttagttaaa gctggatata
     6301 ctgcaaaata agtacatttt ttatatgtaa ataagaacat atagttataa ttttattgat
     6361 tataattata tgttcttttt att
//
LOCUS       DAMJXI010000127         5976 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.134, whole genome shotgun sequence.
ACCESSION   DAMJXI010000127 DAMJXI010000000
VERSION     DAMJXI010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5976
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.134"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            134..700
                     /locus_tag="PC465_003611"
     CDS             134..700
                     /locus_tag="PC465_003611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2650879.1"
                     /translation="MSVSLQKGQRVSLVKDNNPVKNLVVGLGWDMNKLGKKNYDLDAF
                     AIALTNQDKMNVRGDLVYFGNLKHPSKAIIHTGDNLTGKGEGDDEQIIVNLEDIPEYV
                     HKIVFGVSIYKAKKRDQDFGQMNNSFIRLIDSNSKQELFKYNLQEDFSGKVTVLAGEI
                     YRRNEEWKFNALGIGQNEELRELINTYK"
     gene            740..1321
                     /locus_tag="PC465_003612"
     CDS             740..1321
                     /locus_tag="PC465_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2650880.1"
                     /translation="MGITLAKGQKVSLTKSNPGLKKVIVGLGWDINKYDGGFDFDLDA
                     SAFLTGTDGKVTNDGDFIFYNNLKHASGAVEYMGDNRTGVGDGDDEQINVDLSKIPQN
                     IAKISFSVTINEAITRRQNFGQVENSYIRIYNEETNEELIKYELGEDFSIETAIVVAE
                     LYRHNGEWKFNALGSGFEDGLAGLCKNFGVNIG"
     gene            complement(1378..2295)
                     /locus_tag="PC465_003613"
     CDS             complement(1378..2295)
                     /locus_tag="PC465_003613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2650881.1"
                     /translation="MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYG
                     VKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTC
                     VISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
                     DNLVLICSHKHEFYKRDSIKVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWS
                     CYNSEAILRAVVDNFGIAVISELLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFF
                     TENISAFFDISVEYGKKQARKKSRSVNSL"
     gene            2425..4056
                     /locus_tag="PC465_003614"
     CDS             2425..4056
                     /locus_tag="PC465_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2650882.1"
                     /translation="MKVLIIGGVAAGTKTAAKIKREMGDNCSVTILNKGDDISYAGCG
                     LPYYVGKIIEDKSSLIVNTPESFSKLTGAEVRCGVEVTSIDRNAKQVTLKTLSTGEKE
                     NLSYDKLVIATGADPIKPPIPGIDLPGVFFMRTPNDAIKLRDSIENGIKRAVVIGGGF
                     IGLEIAENLSAMGIRVSVVDMAEHVMPGFDTDFAEYVENHMADKGIMIFTGDQVVGIE
                     GENKVEKLRTKNRAIKTDLVVMSVGIRPNTGFLKDTGLEFAPNNTIIADEYMLTNDKD
                     IYVVGDCAFVKNSLTNKPTWSPMGSSANHEGRICAQNISGKSKTYNGVLGTTVVKLPE
                     LNAGKTGLSKEIAEKEGYNVCSVTIATDDKAHYYPGASNFIIRMVAEKNTRKLLGVQV
                     MGPGAVDKIVDIAATAITLGADLYSLESMDLAYAPPFSTAIHPFVVAVNVLQNKLNGE
                     LDSVLLDEIEDFDSWTKLDVSKAPSIPSLRYIPVGEINGEIEGLAKDEKILLICAKGK
                     NSYMAQNRLRRFGYTNTKVLEGGTLFYPNLKVMEE"
     gene            4059..5006
                     /locus_tag="PC465_003615"
     CDS             4059..5006
                     /locus_tag="PC465_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013378669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HDF2650883.1"
                     /translation="MSNVTAEQKKEVKGRGFLPSRDGEHFAARIITVNGVINASQAKK
                     IAEAAEKFGNGQLAFTTRLTVELPGVKFEDIEALSEFIASENLITGGTGSRVRPVVAC
                     KGTVCVHGLADTQALAAEIHEEFYKNWYDVKLPHKFKIGVGGCPNNCIKPDLNDLGIV
                     GQRVPDYDSELCVGCKKCAVVEFCPVKAAKLTDKGKLEIDSNLCNNCGKCIESCNFDS
                     IEEKESGYKVYIGGKWGKSVRPGTQIDRLFSKEELMTLIEKAILLFREQGNTGERFGI
                     TIDRIGADKFIEMLLSDEVLERKEEILEALLHLTGGAVC"
     gene            complement(5291..5554)
                     /locus_tag="PC465_003616"
     CDS             complement(5291..5554)
                     /locus_tag="PC465_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1883 domain-containing protein"
                     /protein_id="HDF2650884.1"
                     /translation="MEYSYSKMNLKKGDIVEVNLEKQANVILLDHINYVKFKNQRNYD
                     YYGGFAKKNPCRMRVPNTGTWYLVVNQDGNSGIVNFSINTIQN"
     gene            complement(5653..5898)
                     /locus_tag="PC465_003617"
     CDS             complement(5653..5898)
                     /locus_tag="PC465_003617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650885.1"
                     /translation="MFIDEELEGYILTCKISEDFKNIPEYSDEEFYVTVYKDESSDSG
                     YYALLENKEERVVWDGEVVANNIFNNLWIVVNKVKTG"
BASE COUNT         2150 a          817 c          983 g         2026 t
ORIGIN      
        1 tattcatgta gttatataat aaataattta taaatatagc caacttagcc taaatacgta
       61 tataatatag ctaatatggt tcttatactt gataccatca ataaaactaa aaatataaaa
      121 aggagaactt aaaatgagtg ttagtttaca aaaaggacaa agagttagct tagtaaaaga
      181 taataatcct gtaaaaaatc tagtagtagg cttaggatgg gatatgaata aattgggtaa
      241 aaaaaattat gacctagatg catttgcaat agcattgact aaccaagata aaatgaatgt
      301 tagaggtgac ttggtttatt ttggaaatct taaacaccct tctaaagcta ttatacacac
      361 tggagataac ttaactggaa aaggtgaagg tgatgatgaa caaataattg ttaatttaga
      421 agacatacct gaatatgtac ataaaatagt ttttggagtt tctatataca aagctaaaaa
      481 aagagaccag gattttggtc aaatgaacaa ctcttttata agattaattg attcaaattc
      541 caagcaagaa ttatttaaat ataatcttca agaagacttt tctggtaaag taacagtttt
      601 ggcaggagaa atttatcgta gaaatgaaga atggaaattt aatgctttag gaattggtca
      661 aaatgaagag cttcgtgaat taattaatac atataagtaa taattacaat aaaaaattta
      721 taatgaggag ttggtttaaa tgggtataac tttagcaaaa ggacaaaaag taagtttaac
      781 aaaaagtaac cctggtctaa aaaaagtaat agtaggacta ggatgggata ttaataaata
      841 tgatggtggc tttgatttcg atttagatgc ctctgcattt ttaactggaa ctgatggaaa
      901 agtaacgaat gatggagact ttatattcta taataattta aaacacgctt ctggagctgt
      961 tgaatatatg ggtgataata gaacaggtgt tggtgatggt gatgatgaac aaataaatgt
     1021 agacttatct aaaatacctc aaaatattgc taaaatatca tttagtgtta ctataaacga
     1081 agcaattaca agaagacaaa atttcggaca agttgaaaat tcatatataa gaatatataa
     1141 tgaagaaact aatgaggaac ttattaaata tgaattgggt gaagatttta gcatagaaac
     1201 agcaatagtt gtggcagaac tatatagaca taatggagag tggaaattta atgctttagg
     1261 ttctggattt gaggatggac ttgcaggatt gtgtaaaaat tttggcgtta atataggcta
     1321 atatatctaa ataaaaataa gagtatattt atatactctt atttttattt agatatatta
     1381 taaactgttt acacttctac tcttctttct cgcttgtttt ttcccatatt ctactgaaat
     1441 atcaaaaaat gctgaaatat tttctgtaaa aaacttgctt ctatgatatg caatatcaaa
     1501 tgtcctatgt aaattaatac cttcaatatc acaagcccac aaaagatgct tttttaaata
     1561 atcctcaata agtaattcgg atataactgc aatgccaaaa ttatctacaa ctgctcttaa
     1621 tatagcttca gagttataac atgaccatct aatattcatt gggattttta attcttttaa
     1681 ttgcttttct aattgtgctc ttgtaccact tcctaattca cgcataatta atggttgatt
     1741 tgaaagttct gaaactttta tagagtctct tttgtagaac tcatgcttgt gtgaacatat
     1801 aagtacaaga ttatcattaa taatgctttt tgtaacaata tctgggtgct taatttttcc
     1861 ttctacaatc gcaatatcta attcactatt aagtaatttt tttgcaatca gtcttgtatc
     1921 ttctacaaat acttcaggtt ctataagagg atttaccttg tataattcta acattattgg
     1981 acttattaca catgtaccaa cagttactgt tgccccaact cttatacgga tattttttgc
     2041 acaatgcttc atacaatcat tcatttcttc atttacagct aaaagatgcc tcccatatcc
     2101 aagaagtttt ttccctgcct cagttaaata taattttttt gaaattctat caaatagctt
     2161 aacaccatac tctttttcta tttctgaaat agcttggcta actgatgact gggtaatata
     2221 catatttctt gctacttcac tcattttacc acattcagca accttaacaa agatttcaag
     2281 actacgaatt gtcatattat cacaacctta gcaaacatta gtaaatgctt atgattttat
     2341 taatatttta gtattttaca aatatattgt caagaagtat aattttatta tagagttata
     2401 aagtagattg gagtgtgata tattgtgaaa gtattaatta taggtggagt tgctgctgga
     2461 acaaaaactg ctgcaaaaat aaaacgtgaa atgggtgata attgctctgt tacaatacta
     2521 aataaaggtg atgatatttc ttatgcaggt tgtggtcttc catattacgt tggtaagata
     2581 attgaagata aatcatcttt aatcgtaaat acacctgaaa gtttttctaa actaacagga
     2641 gcagaagttc gttgtggagt tgaagttaca tctattgata gaaatgcaaa acaagtaact
     2701 ttgaaaacgc tttcaacagg agaaaaagaa aatctaagct atgacaaact tgtaattgct
     2761 acaggggcag acccaataaa accaccaata cctggaatag atttacctgg agtattcttt
     2821 atgcgtactc caaatgatgc tataaaacta agagattcta ttgaaaacgg tattaagaga
     2881 gctgttgtta ttggtggagg tttcattggt cttgaaattg ctgaaaatct ttctgcaatg
     2941 ggtatacgtg taagtgttgt tgatatggct gaacatgtta tgcctggatt tgatactgat
     3001 tttgctgaat acgttgaaaa tcatatggct gataaaggca taatgatttt tacaggtgac
     3061 caggttgtag gtattgaagg tgaaaataaa gttgaaaaac ttcgtactaa aaatagagct
     3121 attaaaacag atttagtggt tatgtcagtt ggaatccgtc ctaacacagg ttttctaaaa
     3181 gacacaggtt tagaatttgc ccctaataat acaattattg cagatgaata tatgcttaca
     3241 aatgacaaag atatatacgt agttggagac tgtgcttttg taaaaaattc tttaacaaat
     3301 aaacctacat ggtcacctat ggggtcatct gcaaatcatg agggtagaat ttgcgcacaa
     3361 aatatatctg gaaaatctaa aacttacaat ggtgttcttg gaacaacagt agtaaaatta
     3421 cctgagctca atgcaggaaa aacaggtcta agtaaagaaa tagctgaaaa agaaggttat
     3481 aatgtttgct ctgtaaccat agctactgat gataaagctc attattatcc aggtgcatct
     3541 aattttatta taagaatggt tgctgaaaaa aatactagaa aattattagg tgttcaagtt
     3601 atgggacctg gagcggttga taaaatagta gatatcgctg ctactgcaat aactttaggc
     3661 gctgaccttt attcattaga aagtatggac cttgcatatg caccaccttt ttcaacagct
     3721 attcaccctt ttgtagtggc agtaaatgtt ttacaaaata aacttaatgg agaacttgat
     3781 agtgttttac ttgacgaaat tgaggatttt gacagttgga ctaaacttga tgtttcaaaa
     3841 gctccttcta ttcctagttt acgttatatt cctgttggtg aaattaatgg agaaattgaa
     3901 ggccttgcta aggatgaaaa aattcttctt atatgtgcta aaggtaaaaa tagctatatg
     3961 gcgcaaaatc gcttaagacg ctttggctat acaaatacga aagttcttga aggtggaaca
     4021 ctattttatc caaatcttaa ggtaatggag gagtaaatat gagtaatgtt acagcagaac
     4081 aaaaaaagga agtaaaaggt agaggttttc taccaagcag ggatggagaa cattttgcag
     4141 cacgtataat aactgtaaat ggtgtaataa atgcatcaca agcaaaaaaa attgcagaag
     4201 ctgctgaaaa attcggaaac ggtcagttag catttactac tagactaaca gtagaattac
     4261 ctggtgtaaa atttgaagat attgaagctc taagtgaatt tattgctagc gaaaatctaa
     4321 taacaggtgg aactggatca agggttcgtc ctgttgtggc ttgtaaaggt actgtttgtg
     4381 ttcatggtct agctgataca caggcacttg ctgctgaaat acacgaagaa ttttacaaaa
     4441 attggtatga tgtaaaacta cctcataagt tcaaaattgg tgttggtgga tgccctaata
     4501 actgtattaa acctgaccta aatgatcttg gaattgttgg tcaacgtgta cctgactatg
     4561 attcagagct ttgtgttggt tgtaaaaaat gtgctgttgt agagttctgt cctgttaaag
     4621 cagctaaatt aacagataaa ggtaaacttg aaatagatag taatctatgt aataactgtg
     4681 gtaagtgtat agaaagttgt aattttgata gtattgaaga aaaagaatct ggttataaag
     4741 tctatatagg agggaaatgg ggaaaatcag ttcgtcctgg aacacagatt gatagattat
     4801 tttcaaaaga ggaacttatg actttaattg aaaaagcaat tcttttattt agagaacagg
     4861 gtaacacagg tgaacgtttt ggaataacta tcgatagaat cggtgctgat aaatttatag
     4921 aaatgctttt atcagatgaa gttttggaaa gaaaagaaga gatactagag gctcttttac
     4981 accttacagg tggagctgta tgctaacaat aaatatttta attgtacaga taacctatgg
     5041 aaaaaatttt agttaagaat aattaaaatt ctatatatga tatatgataa atgaggctat
     5101 ctcaaaacac agatacgcct ctttttcatt gttgaaatga taaagtatat ttgagttcat
     5161 ataaaaaaga gtgtctcgtg aattataaaa ttcattttga ggcacccaca ttattttata
     5221 ataattgctt attaatttta ttttaactat ataaaaagta caaaaagtaa gaatatccaa
     5281 tattctaaaa ttaattttga attgtattga ttgaaaagtt tactattcca ctatttccat
     5341 cttgatttac tactagatac catgttccag tattaggaac tctcattcta catggatttt
     5401 tctttgcaaa tccaccatag taatcataat ttctttgatt tttaaatttc acataattta
     5461 tatggtctaa caatattaca ttggcttgtt tctctaaatt tacctctaca atatcccctt
     5521 tttttaagtt catcttacta taactatatt ccattgaatt actcctccag tatcgaataa
     5581 tctttgttat ttactcatct caaatatgta aaaattcatt taaaatatta caaatactat
     5641 ataattagac tattatccag ttttaacctt atttactaca atccaaaggt tattaaaaat
     5701 attattggca acaacttctc catcccatac aactctttct tctttatttt ctaataaagc
     5761 atagtaccca gagtcagaac tttcatcttt atagactgta acataaaact cttcatcact
     5821 atattcaggt atatttttaa agtcttcaga tattttacat gttaatatat aaccttctaa
     5881 ttcttcatct ataaacaaag caattcctcc aatctctata tttttactaa ttataccata
     5941 ttatgtcata aactttttat tttattacaa atttct
//
LOCUS       DAMJXI010000128         5923 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.135, whole genome shotgun sequence.
ACCESSION   DAMJXI010000128 DAMJXI010000000
VERSION     DAMJXI010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5923
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.135"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(129..536)
                     /locus_tag="PC465_003618"
     CDS             complement(129..536)
                     /locus_tag="PC465_003618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650886.1"
                     /translation="MSKVAKATFYLMIVTIISKILGMGRELVLSSIYGTGLYTESYLT
                     AMNIPNIIFAAIGTAIVTTFIPMYQDISSKQGEKQALKFLNNVLNIIVGICIVVAILG
                     VIFSKQLVSIFAIGFEGERFLLTVKFTKILIKK"
     gene            complement(1010..1894)
                     /locus_tag="PC465_003619"
     CDS             complement(1010..1894)
                     /locus_tag="PC465_003619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2650887.1"
                     /translation="MDTKKENNYENYICVGSSNVSNAMKMYLKEIEEYKMLSAGEEVE
                     LAKEIINSSSVAKEKFINSNYRLVVSIAKRYKRDSIDMLDLIQAGNIGLIKAVEKYDY
                     KKGYKFSTYATWWIKQSITRYIDDCENTIRIPIHLHQRINFVKKKKQELLNVLLREPT
                     IDEIADACGLEVDKVLELLRRDKNVVSLDTPLKEDEDSSLVEFIPSDADFKDVVIHEV
                     EQHNLKEKIEELLTGLGEQEQQVLRMRFGIDDDDPKTLEQIGKVFGVTRERIRQIEAK
                     AIRKLRHPSKLKQLKHFY"
     gene            complement(2185..2661)
                     /locus_tag="PC465_003620"
     CDS             complement(2185..2661)
                     /locus_tag="PC465_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HDF2650888.1"
                     /translation="MSKELVKDRVIKYLIEDLLVPQDMIDTNVELAEFEEGAEGILDI
                     VVNVKDEEDYYAPVMIVQCLDEDVELEGEVLQKQIEFLEEVDNITMSGRLVLTNGDAM
                     MYADWRGEEYDTEAALPTYDIMVKEFHEMEQQAKDLEEHHHHDENCGCGCNHHHEN"
     gene            2928..4103
                     /locus_tag="PC465_003621"
     CDS             2928..4103
                     /locus_tag="PC465_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HDF2650889.1"
                     /translation="MKFKKQISSIVVSTMLVLGSMNLSYADGTNVVTLGANLSESQKQ
                     QMLNYFGVKKDQVLVLDVTNAEERQYLQGVATEGQLGKVTISCSYVEPTKKGNGINVK
                     TANLTWVTSSMIASTLTTAGLEDANVIAAAPYPVSGTGALTGIMKAFEDASGKKLDET
                     KKEIASEELVVTGDLGDDIGQEKATGVMNDIKTEIVKNGTKDTNQIANTINNVVNNYN
                     ITITPEQKEQIKGVMKKIADQNYDYNSMKNTLDNVSDNVNEQLKKLGESVKGSGILDT
                     IGGWFSGIGDWFSGLFSGGDKKDLGILNNTNDESLGSDAVINSTEGVQINPQNNTNSN
                     NDSDTNSSKNDTSSNNENNDSSQTNENNTTNNSENQSNNNDSVGFFEKIKNWLSGLF"
     gene            complement(4184..4987)
                     /gene="proC"
                     /locus_tag="PC465_003622"
     CDS             complement(4184..4987)
                     /gene="proC"
                     /locus_tag="PC465_003622"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDF2650890.1"
                     /translation="MKKIGFIGAGNMASAMIGGIVNSKLVEPNMVIASAYSQGTLDRI
                     DANFGINTTKDSKEVTRTSDIVIVAVKPDIYDDILEEIKDFIDDNKIIVTIAAGKSIK
                     DIESIIGEDKKIVRTMPNTPALVNEAMSSLSINKNINKEDLEAVTEVFNSFGNTEVVP
                     EYLIEAVIGASGSAPAYVFLFIEAIADAAVIAGMPRPQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPGGTTIEAVKVLEEEGFRASVIKAICACIEKSKKMSE"
     gene            complement(5027..5611)
                     /locus_tag="PC465_003623"
     CDS             complement(5027..5611)
                     /locus_tag="PC465_003623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2650891.1"
                     /translation="MNKDIGAKIKQLRTQKQMTLKDMSEKTNLSIGFLSQLERGLTSV
                     ATDSLGKIASVLDVELTYFFMKPKEHKRAVLRSYEKEVFDVENSTFIHYHLSSSLKEK
                     TMLPRLIEILPSKSSEEICCYVHEGEEFVYVLEGTLTVFLGDEQIEMYPGDTIHYNSE
                     KNNHNWVNYTNKVVKILVVSIPNPFEKSDAVKEA"
BASE COUNT         1970 a         1011 c          670 g         2272 t
ORIGIN      
        1 ttagctttag gggtttccag caattcaagt agtattggat aggttctatc ctatctctac
       61 atataggttt ccctatatgc tgactatttt agctactaac tcatgactaa agtcacgagt
      121 gtgcgtagct attttttaat caatatttta gtaaatttta cggtaagtaa aaacctctct
      181 ccttcaaatc ctatagcaaa tatacttaca agttgctttg agaaaataac tcctaatata
      241 gctacaacta tgcatatacc aactattata tttaaaacat tgtttaaaaa ctttagtgct
      301 tgcttttcac cttgtttact acttatatct tgatacattg gaataaaagt agtaactata
      361 gcagtaccta ttgctgcaaa tataatattt ggtatattca tagctgttaa ataactctct
      421 gtatataagc ctgtaccata aattgatgat aatactaatt ctctacccat tccaagaatc
      481 ttagagatta tagtaactat catcaaataa aaagttgctt tagctacctt gctcatttta
      541 tcactccact tctaacatac ctctttttaa tcaagtaaaa tttagctcat tagatataat
      601 tctatcaact aatttgcctt gcttagccct atcaaaatat aattaacacc tatttcttaa
      661 tatatcacaa actacattat tcttcatatt tttttatttc tccaataagt tttacatttt
      721 tcctatataa attgtatagc ttcaattata ttcaaagaaa tggagttgct acccgataac
      781 tttaaaagta aaaaacagat tttattatct ttttaaacta tattctaaca tattttgtcc
      841 atattgagaa attttactaa actattatgt actttattaa ataaataaaa taacagcaca
      901 cctataaaat acaagtgtgc tgttcataaa cagattttat aaaaaaataa ttcctaagta
      961 gagattaaca tgctttctca tactctcata tataatgtgt ctaaaaatat taataaaaat
     1021 gctttaattg ttttaactta cttggatgtc ttaattttct tattgcttta gcttctatct
     1081 gtcttattcg ttctctggta actccaaata cctttccaat ctgttctagt gttttagggt
     1141 catcatcatc aattccaaat ctcattctta aaacttgctg ttcttgctct ccaagacctg
     1201 taagtagttc ttctatcttt tcttttaaat tatgctgttc aacttcgtgt attacaacat
     1261 ctttaaaatc agcatctgat ggtataaatt caactaaact actatcctca tcttctttta
     1321 atggagtatc caaagataca acatttttat ctcttcttaa taattccaac actttgtcaa
     1381 cttctaagcc acatgcatct gcaatctcat ctatagttgg ctctcttaat aacacattta
     1441 aaagttcttg tttctttttc tttacaaaat ttattctctg atgaagatgt ataggtatcc
     1501 taatagtatt ttcgcaatcg tcgatatatc ttgttatact ttgttttatc caccaagttg
     1561 cataagtgct aaatttgtat ccttttttat aatcgtactt ttctacagct tttataagtc
     1621 ctatatttcc tgcttgaatt aaatccaaca tatcaatact atctctttta tatctctttg
     1681 ctatgctcac taccaaccta taatttgaat ttataaattt ttcttttgct actgaagatg
     1741 agttgattat ttccttagcc agctctacct cttctcctgc tgacaacatt ttgtattcct
     1801 ctatttcctt taaatacatt ttcatcgcat ttgatacatt tgatgaaccc acacaaatat
     1861 aattttcata attattttct tttttagtat ccataatcaa accccttcta ttcatagaat
     1921 ttgctaaaac aaaaataaat aatttaaacc tacataatct acaattacat aatatcccat
     1981 tctttaaatg aattgttttg tatattatgt atacaaattt ataaaaacta tacctataat
     2041 attattctac ttctaacagc aatatcctcc ttatatatat aatttatttt attatatgtt
     2101 gttatattct tagttttttg aatgatatat gtctaaaaaa agactgttta ctaaacagtc
     2161 tttttttata tatatgctca atatttaatt ttcatgatga tgattacatc cacatccaca
     2221 attttcatca tggtgatgat gttcttctaa atcttttgcc tgttgttcca tttcatgaaa
     2281 ctcttttacc attatatcat aagttggaag agctgcctca gtatcgtatt cttcccctct
     2341 ccaatcagcg tacatcatag catctccatt agttaaaacc aatctacctg acatagttat
     2401 attatccact tcttctaaaa attctatttg tttttgtaaa acttctcctt ctaactccac
     2461 atcttcatct aaacattgca ctatcattac aggtgcataa taatcttctt catctttaac
     2521 atttacaaca atatctaaaa ttccttctgc accttcttca aattctgcca actcaacatt
     2581 tgtatcaatc atatcttgag gtactaataa atcttctatt aaatatttta ttactctatc
     2641 ttttactaat tcttttgaca tttatttttc tccttccgat tctataacat tatcataatc
     2701 atttctatat tatagtatac tacattaatt gttttttcaa tctcttacaa aaattatttt
     2761 tttattatct tccttatatt ccctttttta ttacaaagtt gtaatcgcat tgatttaaaa
     2821 aatagtttat atttagtata atagaaatgt agcacatatt tttattcaat atattaataa
     2881 aaaaatagat tgaaaatgta atgtatgtta aatctaggag gaatattatg aagtttaaaa
     2941 aacaaattag ttctattgtt gtgtctacta tgcttgtact tgggagtatg aacctttctt
     3001 atgcagacgg tacaaatgta gttacacttg gagctaactt atcagagtct caaaagcagc
     3061 aaatgcttaa ttactttgga gtaaaaaaag accaagtctt agttttagat gtaacaaatg
     3121 cagaagaaag acagtattta caaggtgttg caacagaggg tcaacttgga aaagttacta
     3181 tctcttgctc atacgttgaa cctactaaaa aaggaaatgg aattaatgtt aaaacagcaa
     3241 acttaacttg ggtaactagt tcaatgattg cttcaaccct tacaacagct ggtcttgaag
     3301 atgcaaatgt tattgctgct gctccatatc ctgtaagtgg tactggagca ttgacaggaa
     3361 tcatgaaagc atttgaggat gcttcaggaa agaaacttga tgaaactaag aaagaaattg
     3421 cttctgaaga attggtagtt acaggtgact taggagatga tatagggcaa gaaaaagcaa
     3481 caggtgtaat gaatgatata aaaacagaaa ttgtaaagaa tggtacaaaa gataccaatc
     3541 aaatagcaaa tacaataaat aatgttgtaa ataattacaa tattactatt acaccagaac
     3601 aaaaagaaca aattaaaggt gtaatgaaaa aaatagctga ccaaaattac gattacaata
     3661 gcatgaaaaa tacactagat aatgtatcag ataatgtaaa tgaacaatta aagaaattag
     3721 gtgaaagtgt taagggttct ggtatactag atactattgg tggatggttt agtggaatag
     3781 gagactggtt ctctggttta ttctcaggcg gagataaaaa agatttggga atcttaaata
     3841 acactaatga tgagtctctt ggctctgatg ctgtaataaa ttctacagaa ggtgttcaaa
     3901 taaatccaca aaataatact aattctaaca atgatagtga tacaaatagc tcaaaaaatg
     3961 atacttcaag taataatgaa aataacgata gttctcaaac aaatgaaaac aacacaacaa
     4021 ataattcaga aaatcaatca aataataatg actcagttgg tttctttgaa aaaataaaaa
     4081 attggctttc aggcttattt tagaaattaa acaaataaaa agaattgcct aaaatggaaa
     4141 ttttctataa aaggcaattc tctttattta caataaattt ttattactca ctcatttttt
     4201 tagatttttc tatacatgca catattgctt ttatcacaga agctctaaaa ccttcttctt
     4261 caagtacttt aactgcttct atagtagttc caccaggtga acataccata tcttttaatt
     4321 caccaggatg ttttcctgtc tcaagtacca tttttgcaga acccataaca gcctgtgatg
     4381 caaacttata tgcttgtggt cttggcattc ctgcaattac tgctgcatct gctatagctt
     4441 ctataaataa aaatacatat gctggtgcag aaccacttgc accaattaca gcttctataa
     4501 gatactctgg tactacctca gtatttccaa aagaattaaa tacttctgta actgcttcta
     4561 agtcttcttt gtttatattt ttatttatag aaagagaaga catggcttca tttacaagag
     4621 ctggagtatt tggcatagtt ctaactattt ttttatcttc tcctataata gactctatat
     4681 cttttataga ttttcctgct gctattgtaa ctataatttt attgtcatct ataaagtctt
     4741 ttatctcttc caaaatatca tcatatatat ctggtttaac agctacaatt actatatcag
     4801 aggttctagt tacttccttc gagtcttttg tagtatttat tccaaaattt gcatctattc
     4861 tatcgagagt tccttgacta tatgctgatg ctataaccat attaggttca actaattttg
     4921 aatttactat tccccctatc atagcgcttg ccatatttcc tgcacctatg aatccaattt
     4981 ttttcacttt agtacctcct tattgactaa tagtaatcgt taaaatttaa gcttctttaa
     5041 ctgcatcaga cttttcaaat ggatttggta tacttactac caaaattttc actaccttat
     5101 tagtatagtt gacccaatta tgattgttct tttcactatt atagtgtatt gtgtctcctg
     5161 gatacatttc tatttgttca tctcccaaaa acactgtaag agtaccctct aatacataca
     5221 caaactcctc accttcatgt acgtaacaac aaatttcctc actactctta cttggaagaa
     5281 tttcaattaa tcttggtagc attgtttttt cctttaaact agatgataaa tgataatgta
     5341 taaatgttga gttttctaca tcaaatactt ctttttcata acttcttaat acagctcttt
     5401 tatgctcttt tggcttcata aaaaagtaag ttaattctac atctagtaca cttgctattt
     5461 ttcctaagga atctgttgcc acacttgtta atcctctttc aagttgtgat aaaaaaccaa
     5521 ttgacaagtt tgttttttca ctcatatcct tcaacgtcat ttgcttttga gttctgagtt
     5581 gctttatttt tgctcctatg tccttattca aaaccatcac ccctaaataa ttttaatttt
     5641 ttcataatat aaatacaaaa atataaatat aggtactgaa cctatcttta tttcatttaa
     5701 aaaaattttt ataagtatta ctataattta tcaatctttt tttgtctaca tttttacgat
     5761 tatttacgat ttatttttca catatgtata tttaatcttg ccaactaaat atacattttt
     5821 tataagcatt tactctttat ataataaaac ttaagttgtt catgtagtct tcttctggtt
     5881 taattattaa aatttcaaat tatattatta tttctacaca tta
//
LOCUS       DAMJXI010000129         5761 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.136, whole genome shotgun sequence.
ACCESSION   DAMJXI010000129 DAMJXI010000000
VERSION     DAMJXI010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5761
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.136"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            329..475
                     /locus_tag="PC465_003624"
     CDS             329..475
                     /locus_tag="PC465_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650892.1"
                     /translation="MTAYIASLKEYYSFIETQIGDFIKKYGEDVVELCLHRVMILLCE
                     CGLA"
     gene            1307..2221
                     /locus_tag="PC465_003625"
     CDS             1307..2221
                     /locus_tag="PC465_003625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2935 domain-containing protein"
                     /protein_id="HDF2650893.1"
                     /translation="MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTNKNYNLAMEA
                     DHYKKQFEDLLSYTVSASNGIIRPDILYSEELVTTLTSVAEQKTEEFTGIEINKNITT
                     RELNLQSGVNPQVGQDLVNYVAQLNSDAIRLLDGLINFKERVLDGVLSCTIFTSNYPL
                     LLEHIIHEANLYRSYVVDLENKIDIESKNAKEIELFWDHIMMEHALFMRGLLDPSEGE
                     LINTSNDFAIKFNELIEKTNEMTDSNIKNITEETLNETVEFKDFKEAGASGIEQCKIK
                     SIILPLLADHVLREANHYIRILESYKNM"
     gene            2611..3258
                     /locus_tag="PC465_003626"
     CDS             2611..3258
                     /locus_tag="PC465_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HDF2650894.1"
                     /translation="MIRQTPLEKRYDKLGPHIVTALKKRYFDAYYCKTRNEALQQILD
                     LIPQNHVVSWGGSETLKEMGVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFL
                     MSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASP
                     AVVQRFQDVNTPCYINGSCIDCTSPESICAYMVTTRISRPAKKIKVILVGENLGL"
     gene            complement(3425..3994)
                     /locus_tag="PC465_003627"
     CDS             complement(3425..3994)
                     /locus_tag="PC465_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2650895.1"
                     /translation="MKKFIICIIMFAISVLVLAGCTNDNKIKNEVDSMFNSIKTQDAD
                     TVDKYFPKSGLGNLIYEDKEGFKMYSKNMTWEISDIKNNKDKVTVDLKINNTDMVSIL
                     KKNPPKLGEMMPNPTMKDIDSAKKKEFNITLELVKSGDNYVCKVNQESAMKLLNVITG
                     GGIDYLADYNKDYYKQLDEEQKNYENKNS"
     gene            complement(3999..4898)
                     /locus_tag="PC465_003628"
     CDS             complement(3999..4898)
                     /locus_tag="PC465_003628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2650896.1"
                     /translation="MKLLSKVNNNIRLITQVAFTALTNGYVNGFLEGTIYGGESKKLC
                     VPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPF
                     GLVQDLLHKVPFPVKIKKVYGDKYLKYLKYIVLIMFVIILPVAIVNVAGGGNPWFCKW
                     ICPSGTLLGGIPLILGNENLRESIGFLFSWKLSILLLILLMSIITYRPFCKYICPLGA
                     IYGFFNPISIYRFKIDKDKCTNCTACQTKCKLDIPIYKDVNSPDCIRCGECIKVCPQN
                     AITTTFSKDKKENNICAKKYRGI"
     gene            complement(4909..5058)
                     /locus_tag="PC465_003629"
     CDS             complement(4909..5058)
                     /locus_tag="PC465_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650897.1"
                     /translation="MSNFIKDNKKGISIIAISIIFIALGTYRGETNTVLTKAIMICLE
                     CIGIG"
     gene            complement(5051..5635)
                     /locus_tag="PC465_003630"
     CDS             complement(5051..5635)
                     /locus_tag="PC465_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HDF2650898.1"
                     /translation="MKRFFIVVLGCIFVLGMISGCSKKESKPVEKNKNNSEWFSNLDT
                     EDVDGNKVTKEIFSNKELTLINVWTTWCGPCVGEMPELEALSKEYESNNSNVAIKGLV
                     VEVDKTDMRTGLSNEEKNLVKDIMKKSDATYQQLTVSEELKKTDFKRVMEFPTTYFVD
                     KKGNFVGEKVVGANSKEDWKKIIDERLKMVKANE"
BASE COUNT         2116 a          863 c          662 g         2120 t
ORIGIN      
        1 taaattcctt aaaagtatga ttaattataa ttatataagt atattcttat tacacttata
       61 ttaatttata ttaaatatct actaactcaa atattcataa ttaaacttta aactggataa
      121 attttctttt aagaatgaaa gtttatccag ttttgcgatt ataataacca gttttacata
      181 tccacttgta aaatatatct aagcaatata tcatactata tagatttatg agtgaaataa
      241 tatctgctat ttactgaata tttttatttt tcgtttttta gggggattag ttgtctttaa
      301 agataagatt gatgaatgtg ttcatataat gactgcatat attgctagtt taaaagaata
      361 ctattcattc atagaaactc aaattggtga ttttattaaa aaatatggag aagatgttgt
      421 agagttatgt ctccatagag tgatgattct actatgcgaa tgtggtttgg cataaaatta
      481 aatgtattaa aatgggtaag aagaatccta tataatattc ttcttaccca ttttaatata
      541 tcaatttcat agcttatcgt ttaaaatatt ttacatccat tactagacaa ctttacattc
      601 tctttttaat tctagtatat ttaaatcatt ttagttgctc cttatttatt cttattactt
      661 gttttatttt ataaataaaa taattcttct taataatgtt ttttattgat attcctatca
      721 cacatccaat tatttatcat tgtcttgaaa ttgtttgcat acttaattta atccaattga
      781 aacaccccag catagaatcc cctgtaaaat agaagttgga ttaaatccta acatctatac
      841 agaaaatact actccaagca caagcaatat aatggaatat atttatcact taatttttta
      901 tactttttaa atcccatacc taaaacatta agtgcagcta ttagaattaa taattgttgt
      961 ggtataaaat tatgcttgct tcatatttat tcattttttg ctataaaagt tcttgtttta
     1021 caaaaaacat ttgttttgta tcaaaataat acttataaat tacataattc tcataaaaat
     1081 ttctagtatt acttgtactc ttaataaata atagccaaca agtaccttaa atcattatat
     1141 ctatatctaa taagaaacac agtaagataa ttttttcgcc cataacttaa taaaaactgt
     1201 tgatattagt agcaattgaa tttagttaat ttatttataa tatacataaa tttaaatatt
     1261 acgaataaag tattataaat aggatacttt ctaaagggag gaaattatga tagataatca
     1321 aaaatatgtt attttatcac tagaattaca tttatttttt tcaagaatta tgaaagagca
     1381 tgctcttttt ttagaagcag gattcacaaa taaaaattat aatcttgcta tggaagctga
     1441 ccactataaa aagcaatttg aagatttatt atcatacact gttagtgcta gtaatggtat
     1501 aattagacct gatatattat attcagaaga gcttgtaact actctcacat cagttgcaga
     1561 acaaaaaaca gaagagttta cagggataga aataaacaaa aacatcacta caagagaatt
     1621 aaatctacaa agtggtgtaa acccacaagt tggtcaagac ttagtgaact atgtagctca
     1681 acttaactct gatgcaataa gattacttga tgggcttatt aattttaaag aaagagtctt
     1741 agatggtgta ctatcatgta ctatatttac atcaaactac cctctacttc ttgaacatat
     1801 aatacatgaa gcaaatttat atcgttctta tgtagttgac cttgaaaata aaatagatat
     1861 tgagtcaaaa aacgctaaag aaatagaatt attctgggac catattatga tggaacatgc
     1921 tctgtttatg agaggattac tagacccctc agaaggtgaa ctaataaata cttcaaatga
     1981 ttttgctata aaatttaatg aattaattga aaaaacaaac gaaatgactg attctaatat
     2041 caagaacatt acagaagaaa ctctaaatga aactgttgag tttaaagatt ttaaagaagc
     2101 aggagcatca ggaatagaac agtgtaagat aaaatctata atattaccac ttttagcaga
     2161 ccatgtttta agagaggcaa atcattatat tagaatattg gagagttata aaaacatgta
     2221 attaaaaatt acttttaaaa taatctttgc atatttagat aaaataaagg tacagttaac
     2281 tgtaccttta ttttttataa acttataaaa tttaaacaag ttattcataa aataaaataa
     2341 taatcatcta taacccacaa ctttatttta tattaaataa aaagtattag tgattatgtt
     2401 ttataggtat ttctttattc agttatttat taaaaactaa tagtaaatct tatactaatc
     2461 gcatatttat gttataacta tattgtaact attttcgtaa tcttaggaaa aggttactta
     2521 taaaattaac cttatacaat aatatatcgt ataatcttaa ttagcataat agttacaata
     2581 ttaaaattta aatatgggag tgattttagt atgataagac aaacaccatt agagaaacga
     2641 tatgacaagc taggtcctca tattgtaaca gcactcaaaa aacgttattt tgatgcttat
     2701 tactgtaaaa ctagaaatga agctttgcaa caaattttag atttaattcc tcaaaatcat
     2761 gtagtatcat ggggaggatc tgaaacactt aaagaaatgg gcgtacaaac tgctgttaga
     2821 gagaaaggat ttaaagttat tgatagagat ttagcaaaaa ctccagaaga aagaactgaa
     2881 attatgcgtc aagcacttct atgcgatact tttttgatga gtagcaatgc aattagtgaa
     2941 gatggacaac tctttaatat tgatggaaat ggcaatcgtg tagctgcaat gatatttggt
     3001 ccaaaaaatg ttatagttgt agctggtatg aataaaattg taaaaaacat tgatgatgca
     3061 atacaaagaa ctagaacaat tgcatctcca gcagttgttc agcgttttca agatgtcaat
     3121 acaccatgct atattaatgg aagttgtata gattgcacaa gtcctgaaag catttgtgca
     3181 tacatggtta ctacaagaat cagtcgtcca gcaaaaaaaa taaaggtaat attggtagga
     3241 gaaaatcttg gtctataaaa tatacataca tgtaaatagc tctataaata ataaaatcat
     3301 atgaaataac ttatttctaa aagtggtaga ataaaagctt ctacaagact ttcattctac
     3361 cacttttata ttcttttaat ttgtgtttct atattattaa ttgctccgat tttcatatat
     3421 attactaact atttttattt tcataatttt tttgttcttc atcaagctgt ttataataat
     3481 ctttattata gtcagctaga taatctatac cacctcctgt aatcacattt aataatttca
     3541 ttgcagattc ttgattaact ttacaaacat aattatcacc agatttaaca agctctaatg
     3601 taatattaaa ttcttttttc tttgcagaat caatatcttt catagttgga tttggcatca
     3661 tttctcctag tttaggagga ttctttttta aaatagaaac catatcagta ttgttaattt
     3721 ttaaatctac agtcacttta tccttattat tctttatatc tgaaatttcc caagtcatat
     3781 ttttagaata cattttaaat ccttctttat cttcgtatat aagattacct aaccctgatt
     3841 ttgggaaata cttatcaaca gtatctgcat cttgtgtttt tattgaatta aacatactat
     3901 ccacttcatt ttttatctta ttatcattag tacaaccagc taacaccagt actgatattg
     3961 caaacattat aatacatata ataaatttct tcattaaatt atatccccct atactttttt
     4021 gcacaaatat tattctcttt tttatctttt gaaaaagttg tagtaattgc attttgtgga
     4081 caaactttta tacattcacc acacctaata cagtctggac tatttacatc tttatatatt
     4141 ggtatatcaa gcttacattt tgtttgacat gctgtacaat ttgtacattt atctttatca
     4201 attttaaatc tatatattga aataggatta aaaaaaccat agattgctcc taaagggcat
     4261 atatacttgc aaaatggcct ataagtaatg attgacatca ataatatcaa tagcaaaata
     4321 cttaacttcc agctaaataa aaatcctatt gattctctta aattctcatt tcctaaaata
     4381 agtggtattc ctcccaaaag tgttcctgaa gggcaaatcc atttacaaaa ccaaggattt
     4441 ccaccccctg ctacatttac aatagcaact ggcaaaataa ttacaaacat tattaagact
     4501 atatacttta gatattttag atatttatca ccataaactt tttttatctt tactggaaag
     4561 ggtactttat gtagtaaatc ttgtacaagt ccaaagggac aaagccaacc acaaacaaat
     4621 ctgccaaaaa aagcaccaaa tgccattaaa aaaccaacaa cataaaatga gaatttatac
     4681 tctctgcttg ataaaactgc ttgtaatgaa cctattggac atgctccaag tgcacctgga
     4741 catgaataac aattcaatcc aggtacacat aattttttac tttctcctcc atatatagtt
     4801 ccttctaaaa atccatttac atatccattt gttaatgctg taaatgcaac ttgagtaata
     4861 agtcttatat tattatttac tttagataat aacttcattc ctcttctcct aaccaatacc
     4921 aatacactca agacaaatca taattgcttt agttaatact gtatttgttt ctccacgata
     4981 tgtacctaat gcaataaata taatactaat tgcaataata gaaatgcctt ttttattatc
     5041 tttaataaaa ttactcattg gcttttacca tttttagtct ttcatctata atttttttcc
     5101 aatcttcctt actatttgca cctacaacct tctcacccac aaagtttcct ttcttgtcta
     5161 caaaataagt tgttggaaac tccataactc ttttaaaatc agttttttta agttcttcag
     5221 atacagtcaa ttgttggtaa gttgcatctg actttttcat aatgtcttta actaaatttt
     5281 tctcttcatt tgaaagacca gttctcatat cagttttatc aacttctaca actaatccct
     5341 ttatagctac attggaatta ttactctcat attcttttga taatgcttca agctctggca
     5401 tttcacccac acatggtcca caccaagtag tccagacatt aataagagta agttctttat
     5461 ttgaaaatat ctcttttgtt accttatttc catcaacatc ctccgtatct aaattactaa
     5521 accattcact attattcttg tttttttcta ctggcttaga ttcttttttg ctacatccag
     5581 aaatcatacc taaaacaaaa atacatccta aaactactat gaaaaacctt ttcatatctc
     5641 acactcctag aatttatata gtatataaaa tcgctgcttg aaataaaaat aacttatctt
     5701 ctatattaaa gtaattatat ttaataaata agagctaatt taaaaaaaga tatacagtta
     5761 a
//
LOCUS       DAMJXI010000130         5719 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.137, whole genome shotgun sequence.
ACCESSION   DAMJXI010000130 DAMJXI010000000
VERSION     DAMJXI010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5719
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.137"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            83..1195
                     /locus_tag="PC465_003631"
     CDS             83..1195
                     /locus_tag="PC465_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2650899.1"
                     /translation="MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRL
                     NEVKESLYNDGFLVPSEITVSEFLLDFLNKYSENISLATYNNYVSICKNYINPSIGKY
                     KIQDLHPVHIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDSIEAPR
                     YKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTI
                     TVNKITSRINGSVILKEPKTESSVRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNN
                     LLFFNKKCEPIAEDVMSKKFKRFLEKNELPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN"
     gene            complement(1403..1879)
                     /locus_tag="PC465_003632"
     CDS             complement(1403..1879)
                     /locus_tag="PC465_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650900.1"
                     /translation="MVKKRLVAVVISLAMISVGNFSYAHSGGHNSSGGHHNKNKSELT
                     RYYCGGHSAHQHNKGFCPYASTKENSGVTISSVHNEKNHKNYFAEKGYNKGYEDGCKG
                     LYNLSVTEAKSDNLYEKEILKSSYEKGYLIGYNEYKAKKVDDVMKKMLDIPMLASI"
     gene            complement(2078..3703)
                     /locus_tag="PC465_003633"
     CDS             complement(2078..3703)
                     /locus_tag="PC465_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2650901.1"
                     /translation="MLQVTGVGLRFGDKELFKDVNLKFTKGNCYGIIGANGAGKSTFL
                     KILSGEIEPNTGSISITDKERMSVLKQDHFEYEEETVLNVVIRGHERLWNIMKEKDAL
                     YMKEDFNEEDGIKAAELEGEFAELDGWDAETNAEKILMGLGITKDMHYKQMKELVGGE
                     KVKVLLAQSLFGKPEILLMDEPTNHLDFKSINWLNNFIMDLEESIVIIVSHDRHFLNQ
                     ICTNIVDVDFGKIQMYVGNYDFWYESSQLALQLAKDQNKKTEEKIAQLKEFIARFSSN
                     ASKAKQATSRKKQLEKLEVEDIQPSRRRYPYVGFTPAREIGNEVLEVHNLTKTIDGVK
                     VLDNVSFRLDRDDKVVFMGDEIATTALFNIVMGELEPDSGEYKWGVTTSQDYLPKNHN
                     KFFDGVEYSLVDWLRQFSEEKSESFIRGFLGRMLFSGEEALKEAQVISGGEKVRCMLS
                     KLMLSNANVLVLDDPTNHLDLESITSVNKGLEKFPGVLLFTSHDHEFISTIANRIIEI
                     TPNGIMDRKMDFDEYLESKEIQDQLAKMYGKDK"
     gene            complement(4041..5060)
                     /locus_tag="PC465_003634"
     CDS             complement(4041..5060)
                     /locus_tag="PC465_003634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HDF2650902.1"
                     /translation="MKLIKTIDAVGQVLCHDITQIIPGEFKGRKFKKGHIVKEEDIPV
                     LLSLGKDNLYVWEKSEGMVHENEGALFLKELTAGENLDFSEIKEGKIDFIAACDGLLK
                     IDVDALFDLNCVGEIMMATLHNNFIVNKGLKVAGTRVIPLVIDEKKLEDAKKVVGNRK
                     IVNVVPFKPKKVGIVTTGNEVFYSRIVDKFGPVIEEKVKGFGCEVIGQTICPDDKEII
                     KSAIKEFISQGAELICCTGGMSVDPDDVTPTAIKETGADLVTYGSPILPGAMFLLAYY
                     GEVPIMGIPGCAMYHKTTVFDIVLSRVLIDEKLDKYDIARYGHGGLCMNCDVCTYPAC
                     NFAKI"
     gene            complement(5057..5626)
                     /gene="mocA"
                     /locus_tag="PC465_003635"
     CDS             complement(5057..5626)
                     /gene="mocA"
                     /locus_tag="PC465_003635"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HDF2650903.1"
                     /translation="MINAVIMASGFARRMGANKLLLNYKGCSIIEHVFREVSKIDFHQ
                     VVVVSQYEEVLLLCNKYGFEYIDNKNANIGQSESIKLGVLNSSKCDGYMFFVGDQPFI
                     DNLYIDKIINTFKLDRDFIVIPRYKDMCGNPVIFPYSKKEELLALKEDEKGKTILKNS
                     SKIKYVEVPKEMLFDIDTKMDYERIGGKL"
BASE COUNT         1947 a          967 c          593 g         2212 t
ORIGIN      
        1 tgtatgcaac tctatttcaa aattattttg tgatatatat atgttataat aaatgtataa
       61 aattttgatt ggtgggttat atatgaatgc atttattaga aaaagaaata aaaactatgt
      121 tgtttacctg gaatttgaag atgaaaagac aggtaaaaga aaacaaaaaa atatgggtac
      181 ttttgataaa aaaagggaag caagtaaaag actaaatgag gtaaaagaaa gcttatataa
      241 tgatggtttt ttagtaccaa gcgaaattac agtgtcagaa tttctattag attttctaaa
      301 taaatatagt gaaaatatat ctttagctac atataataat tatgttagta tttgtaagaa
      361 ttacattaat ccatctattg gaaaatataa aatacaagac ttacatccag ttcacataca
      421 aaactacata gataaactat cttataaact aaatcctcaa tcaattaaga ttcatataaa
      481 tatattgaaa cttgcaataa aaagagctta tagactcaaa ttaataaaag aaaatgttat
      541 ggatagtata gaggctccaa gatataaaaa atttaaaaat gagatttatg atagagaaca
      601 aatgataaaa ttattagatt tagcaaaaaa tacagaaatg gaattaccta ttaatttggc
      661 tattggatta ggtcttagaa tttcagaagt tttaggtcta acttgggata atattgattt
      721 tgaagaaaat acaataacag taaataagat aacttcccga attaatggtt ctgttattct
      781 caaagagcca aagacagaaa gctctgttag aaaaatatct tctcccaaag aattaatgtc
      841 tttattaaaa gaatataaaa taaaacagaa taaaaattta ttaaaatctt ccattagaaa
      901 taataataat ttgttgtttt tcaataagaa atgtgaacct attgctgaag atgttatgag
      961 taaaaaattt aaaagatttt tagaaaagaa tgaattacct catattagat tccatgattt
     1021 aagacactca catgttactt tacttataaa ttctaaagta cctataaagg ttatatccga
     1081 gagagtagga cactcaaata taagtactac tctaagcgtt tattctcatg tacttaaaga
     1141 aatggataaa gaggcttctg acaaaatttc tgaaagttta tttaatgcta attaatatta
     1201 atttatctta gctttaaatt agcttagctt attgagatag attcattaat attaaatgta
     1261 tctatctcaa attaataact acttaaataa tctgttttat tttaatttat cgcctcagtt
     1321 attatacttt tttacgaaaa attatacttt acaataaaaa agatattccc ttatagaaaa
     1381 tatcttttta aatactatat tattatatac ttgctaacat tggaatatct aacatcttct
     1441 tcattacatc atctactttt tttgctttat attcattgta tccaattaaa tatccttttt
     1501 catatgaact ttttaaaatc tctttttcat ataaattatc agatttggct tctgtgacac
     1561 ttaaattata aagcccttta cacccatctt cataaccttt attataccct ttttctgcaa
     1621 aatagttttt atgatttttt tcgttatgta ctgaagatat tgttactcca gaattttctt
     1681 ttgtactagc ataaggacaa aaacctttat tgtgttgatg tgctgaatgt cctccacaat
     1741 aataacgtgt taactctgat ttatttttat tatgatgacc tcctgatgaa ttatgccctc
     1801 ctgagtgagc atatgaaaaa ttccctacac taatcatagc taaactaatt actacagcta
     1861 ctaacctttt cttaaccata atctattccc cccaaaatgt tatatatttt tattatatca
     1921 tctactatat tatatttaaa ttcttaatat acaaaatatt actctattct gctaataaac
     1981 atgtttaaac aacataaaaa acctcctaat atttgattaa aaatttacac actcatgcat
     2041 agcatgtctc aaatattaaa aggttttata ctaataatta tttatctttt ccatacattt
     2101 tagctaattg gtcttgtatc tctttacttt ctaaatactc atcaaagtcc atttttctat
     2161 ccattattcc atttggagtt atctctataa ttctatttgc tatagtagat ataaattcat
     2221 ggtcatgaga agtaaataaa agcactcctg ggaacttttc aagtccttta tttacagaag
     2281 ttatactttc taggtctaag tggttagtag ggtcatctaa tacaagtaca tttgcatttg
     2341 aaagcattag cttactaagc atacatctaa ccttttctcc tccagatata acttgagctt
     2401 cttttaatgc ttcttcacct gagaataaca ttctacctaa aaatcctctt ataaaacttt
     2461 cacttttttc ttcagagaac tgtctaagcc agtcaaccaa agaatattct actccgtcaa
     2521 aaaacttatt atgatttttt ggaagataat cttgagaagt agttactccc catttatact
     2581 ctccactgtc tggttcaagt tctcccataa ctatgttgaa aagtgcagta gtagctattt
     2641 catctcccat aaatactact ttatcatctc tatccaatct aaatgacaca ttatcaagaa
     2701 ccttaacccc atctatagtt ttagttaaat tgtgtacttc taaaacttca ttcccaattt
     2761 ctcttgcagg tgtaaatcct acatatggat atcttcttct tgatggttgt atatcttcaa
     2821 cttctaattt ctctaactgt ttctttcttg atgttgcttg tttagccttt gaagcattag
     2881 aactaaatct agctataaat tcctttaatt gagctatctt ttcttcagtc tttttatttt
     2941 ggtccttagc caattgtaaa gccaattgac ttgactcata ccagaaatca tagtttccaa
     3001 cgtacatttg tattttacca aaatctacgt caactatatt agtacatatt tgatttagga
     3061 aatgtctatc atgtgatact attataacta tagattcttc taaatccatt ataaaattat
     3121 ttaaccagtt tattgattta aaatctaagt ggtttgtagg ttcgtccatt aatagtattt
     3181 caggcttacc aaaaagtgat tgtgctaaca ataccttaac cttttcccca ccaactagtt
     3241 ccttcatttg tttgtaatgc atatctttcg ttatgccaag gcccataagt attttctcag
     3301 cattagtttc tgcatcccat ccgtcaagct ctgcaaactc accttcaagt tcggcagctt
     3361 ttatcccatc ttcttcatta aagtcttcct tcatatacaa tgcatctttt tctttcatta
     3421 tgttccaaag tctctcatga cctcttataa caacatttaa aacagtttct tcttcatatt
     3481 caaagtggtc ctgttttaaa actgacattc tttctttatc agttatagat atactacctg
     3541 tattaggctc tatttctcct gataatattt ttaaaaaagt agattttccc gcaccattag
     3601 ctcctattat tccatagcaa ttacctttag tgaattttaa gttaacatct ttaaatagtt
     3661 ccttatcacc aaatctaagt ccaacacctg taacttgtaa cattaatata ttttcctttc
     3721 tttttgctca taatttattt tatcataaaa ctttgataac atttttatta tatattatca
     3781 cgtaaatagt atatttttta tactaaattt gtgaaatatt tattaaaata atactaaaaa
     3841 ttgtaaattt ataaaaatta acaatctctt atattatact tataaagaaa tcaaattgca
     3901 actttattca ttcttttaca cattgaaaat aagttattat aatttctaaa taaatatgct
     3961 tttcttaaaa catcattcta gctgttttgt ttcatattta aaaagagtac ttaatttgta
     4021 aatactcttt tttaataact ttatatttta gcaaaattac atgcaggata agtacataca
     4081 tcacagttca tacaaaggcc accatgacca tatctagcta tatcatactt atcaagcttt
     4141 tcatcaatta aaaccctaga taaaactata tcaaatactg tagttttgtg atacattgcg
     4201 catcctggta tacccataat tggaacttct ccataataag caagtaaaaa catagctcct
     4261 ggtaatattg gtgaaccata tgtcactaaa tcagctccag tttcttttat agctgttggt
     4321 gtaacatcat ctgggtctac actcatccca ccagtacaac agataagttc tgctccttga
     4381 cttataaatt cttttattgc actctttata atctctttat catctgggca tatagtctgt
     4441 cctataactt cacaaccaaa gccttttact ttttcttcta ttacgggtcc aaatttatca
     4501 acaattctgc tataaaacac ttcatttcct gtagtaacaa ttcctacttt cttaggttta
     4561 aaaggtacta catttactat ttttctatta ccaactactt tttttgcatc ttctaatttt
     4621 ttctcatcta taaccaaagg tatcactctt gttccagcta cttttaaacc tttatttact
     4681 ataaaattat tatgaagagt agccatcatt atttctccaa cacaattcaa atcaaaaagt
     4741 gcatcaacat ctatctttaa tagaccatca catgctgcta taaaatctat tttcccttct
     4801 tttatttcac taaaatctaa attttctcca gcagttagtt cttttaaaaa caatgcgcct
     4861 tcattttcat gaaccattcc ttctgacttt tcccatacat acaaattatc tttaccaaga
     4921 gataataaca ctggaatatc ttcttctttt actatgtggc cttttttaaa ttttcttcct
     4981 ttaaattctc caggtattat ttgagttatg tcgtgacata aaacttgtcc aacagcatct
     5041 atagttttta ttagcttcat aatttacccc caattctctc atagtccatt tttgtatcga
     5101 tatcaaataa catttcttta ggaacttcta catactttat ttttgatgaa ttttttaaaa
     5161 tggttttacc tttttcatct tctttaagtg ccaacaattc ttctttcttg ctatatggga
     5221 atatgactgg atttccacac atatctttgt atcttggaat tactataaaa tctctatcta
     5281 atttaaaagt atttataatt ttatctatat ataagttatc aataaatggc tggtctccta
     5341 caaagaacat ataaccatca cattttgagc tatttaaaac tcctaatttt atagattcac
     5401 tttgacctat atttgcattt ttattatcta tatattcaaa accatattta ttacacaata
     5461 acaaaacctc ttcatattga cttactacta caacttgatg aaaatcaatc ttgctaactt
     5521 ctctaaatac atgttctatt atagaacagc ctttataatt taataaaagt ttatttgctc
     5581 ccattcttct ggcaaagcct gatgccatta tcactgcatt tatcatatat atcatccttg
     5641 gtatttataa tatattgata gttctatgat ttttataata tctctattga tattatctat
     5701 atatataata tcatataaa
//
LOCUS       DAMJXI010000131         5566 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.138, whole genome shotgun sequence.
ACCESSION   DAMJXI010000131 DAMJXI010000000
VERSION     DAMJXI010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5566
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.138"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            478..957
                     /locus_tag="PC465_003636"
     CDS             478..957
                     /locus_tag="PC465_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2650904.1"
                     /translation="MDKTTFTNNILESEQTLYRVSKSILGNDQDCEDAINNAILKAYE
                     KLDSLKEEQYFKTWLIRIVINECNSLRRKRLKSLSFEDVFKNKKIDEKDDYSDLYTAI
                     QSLPKKIKIPIVLYYIEGYSVDEVKEILDIPQGTVKSRLSRGRRLLKTKLENTEVII"
     gene            954..1733
                     /locus_tag="PC465_003637"
     CDS             954..1733
                     /locus_tag="PC465_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650905.1"
                     /translation="MNKNILNNSFPEVPESFHNSLSKTLNSLPEREENYKMINNKTHK
                     LPFRKGLVATLAITLILSTTALAVGHIYSLVGKSSTKATYTSIPTTEQVKKDFNFTPN
                     IVSEFSNGYKFKGAYTVNKKAFDKENNVLGKSKALSFEYKNGNDEISLDTANDVLGKS
                     SDNLKVVDTYKDINISYEAFAQKFVPEGYKMTEQDKIDEKSGKYTFSVGPNNESDKVE
                     VNKFKFLTWKQDGVYYSFTVQDSNLSMNDLVKMAHEVIDAK"
     gene            complement(1983..2483)
                     /locus_tag="PC465_003638"
     CDS             complement(1983..2483)
                     /locus_tag="PC465_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2650906.1"
                     /translation="MIEGIKFIKAEEKYIYSYWQTFDKIAKERKYLAMDEAFPFEETV
                     EFIKNIINKNLPQLFIIDLESDNCIGWCDVLPKTEKVGYLGMGILKEYREKGIGSSLL
                     KQIIDLSKEYGYEKIELDVFKSNSRAIHVYKSLGFVEVNTISSGFTWNDRPVKEEVIQ
                     MELTLI"
     gene            complement(3095..3802)
                     /locus_tag="PC465_003639"
     CDS             complement(3095..3802)
                     /locus_tag="PC465_003639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF2650907.1"
                     /translation="MIFTKSNKYDKDFLMKNMMGPNCIKILEELTSKIKLEKGMRILD
                     LGCGKGISSIFLAKEFDATVFATDLWIEPTENYKRFKEFKLDDKIFPIQAEAHELPYA
                     EGFFDAVISIDSYHYFGNKEGFLDNHISPLVKEGGILAMAMPGLKEDFVDCIPDELIP
                     FWQDNMNFHSITWWNKLWSESESVIVEKCEALNCHDEAWKDWINCDNSYAINDKKMME
                     VENGKYFNTISLIARTK"
     gene            complement(4606..5475)
                     /locus_tag="PC465_003640"
     CDS             complement(4606..5475)
                     /locus_tag="PC465_003640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HDF2650908.1"
                     /translation="MVIIKAIELYKKLDLEFNIKNINDDWSFMNFENDFITSEFRKKY
                     IGLVLDNAQNINKVYTTTFPDKEIIKQVIDKDEKDILIFSHHAMGYIASDEGFPFHDI
                     PLSYMEEMKNRRISFYVLHSPLDNYSDYSTSVSFAKAMGLEIVKPFCKYDDKIEVGVI
                     CKTSLKSIEEIKELIKKSVGHDVKLYDYGDSVLKDGLVAIAAGGGSYPFVAREVAELG
                     INLYITGFTKPLKHFEPVLEFHQIAKDNLINVIGATHYSTEKFACMGMVDYFKNLGLE
                     SEFLQGKYYLEDL"
BASE COUNT         2058 a          827 c          575 g         2106 t
ORIGIN      
        1 gtttatttat gttcatctct atctaaaata atgacatttc taactcttaa ttctcattta
       61 agtttcattg ttttttctta aaagcctact tttagtcaag atactgttat ctttactcat
      121 tatttaaaaa acttatttta aatctgtaca tgaagtaaat aatccaaaag cattgttatt
      181 ctaactactc aacattaaat acttactatt ttctaattta ctcaatataa acacttacta
      241 taaaactaaa tatataaatg gcttctaaag tttaatatat ctacatggct ttatatatga
      301 ggggaaaata ctagaaaaaa atatattata gaatatttgt atagaatagg caaaactttc
      361 aaacttaaat ttatcaaata atcataaaaa aagtgaacca tctatagtaa aattttatct
      421 aataagtgaa aggcaaaaaa gtagcgctac gatttgcata gaagggaagg aacttagttg
      481 gataaaacta catttacaaa caatatactt gaatcagaac agactttgta tcgagtatct
      541 aagtctattc taggaaacga ccaagactgt gaagatgcca tcaacaatgc tattttaaaa
      601 gcatatgaaa agttggattc tcttaaggaa gaacaatact ttaaaacatg gctgattaga
      661 atagtcataa atgaatgtaa ttcattaaga cgcaaacgat taaaatctct atcatttgaa
      721 gatgtcttca aaaacaaaaa aattgatgaa aaagatgact atagcgattt gtatactgct
      781 attcaaagtc tacctaaaaa aattaaaatt ccaatagtcc tttactatat tgaaggttat
      841 tcagtagatg aagttaagga aatattagat atacctcaag gaactgtaaa aagtagatta
      901 tcaagaggaa gaagattatt aaaaactaaa ttagaaaaca cggaggtaat catatgaata
      961 aaaatatatt aaataattcg tttccagaag ttccagaaag ttttcataat agtttaagca
     1021 aaacactaaa tagtttacca gaaagagagg aaaattataa aatgattaat aataaaacac
     1081 acaaattacc atttagaaaa ggcttagttg caactttagc cattactttg atattgagca
     1141 caacagccct tgcagtagga catatatata gtttagttgg aaaatcaagt actaaggcta
     1201 cctatacatc tatcccaact acagaacaag taaaaaaaga ctttaacttt acccctaata
     1261 tagtttctga atttagtaat ggatataaat ttaaaggagc atatactgta aataaaaaag
     1321 catttgacaa agaaaataat gttttaggaa aatcaaaagc acttagtttt gaatataaaa
     1381 atggcaatga tgaaatatct cttgacacag caaatgatgt acttgggaag agttctgaca
     1441 atctaaaagt tgtagatact tacaaagata ttaatatttc ttatgaagca ttcgcacaaa
     1501 agtttgtacc agaaggttat aaaatgacag aacaggataa aattgatgaa aaatcaggca
     1561 aatacacatt tagtgtgggg ccaaataatg aatcagacaa agttgaagtt aataaattta
     1621 agtttttgac atggaaacaa gatggagttt actattcttt tacagttcaa gactcaaatt
     1681 tatctatgaa tgacttagtt aaaatggctc atgaagtaat agatgcaaaa taaacataag
     1741 taataataag ttgtttatga gtttattatt tatgacttta atttttttat tagtaaacat
     1801 ggttgtatct tccatcttta tattttcttt aaatttaata tataaaattt tagatattta
     1861 gctaccttca aaagaaccat tattaaaaag cccttaaaaa tatttctttt atatggaatt
     1921 ttaagggctt taactttatt ttatacaagt gtatatggaa ttttaaagac tttaacttta
     1981 ttttatataa gtgtaagctc catttgaatt acttcttctt ttacaggtct atcattccat
     2041 gtaaaaccac tagatattgt atttacctct acaaacccta aagatttata aacatgaata
     2101 gctctactat tacttttaaa tacatcaagc tcaatttttt catacccata ttcttttgat
     2161 aaatcaataa tttgttttaa aagactactt ccgatacctt tttccctata ctctttaaga
     2221 atacccatgc ctagataacc aactttttca gttttaggta aaacgtcaca ccaaccaata
     2281 cagttatctg attctaaatc aattataaac agttgtggta agtttttatt tataatattt
     2341 tttataaatt caactgtttc ttcaaaagga aaggcttcat ccatagctag atatttcctc
     2401 tcttttgcta ttttatcaaa agtttgccaa tacgaataaa tatacttttc ttctgccttt
     2461 ataaatttta tgccttctat caacttaaca tttccccttt ttaatttttg attgtagtta
     2521 acttatttta tatgattcta ttttataatg ctatataaat tactatatat tagcttaaaa
     2581 tatctttgta tatttctata aaattaaaac caatatatct atctcttgta tctctattaa
     2641 aataattttt aatagtataa taaatatagc tctttaatct tttgagtata tatacttaat
     2701 cattttgaaa tttgatttaa agtataataa aatatataaa aaaatatata aaatggtact
     2761 ataaaatttt tagtcttcat caataccttt tttgctttca ttgttaaagc tattttttct
     2821 attagtttat ttcttataaa acaaacattt agtattaaaa tatatatcac acaatagtat
     2881 ttgcaattta actttaaaaa aataaaaata cccaactgac ctaagcaact cgattgggta
     2941 taaataatct aaaaaatcat ttttgtataa actctttatt taacttacat ttttatttac
     3001 cttctacttt aattcaactt atatttctat gcttcttata ctctcattca acttatattt
     3061 ctacttatct tatactttta taaattcatc acaattattt agttctcgct atcaaagaaa
     3121 ttgtattaaa atactttcca ttctctactt ccatcatttt tttgtcattt atagcatatg
     3181 aattatcaca atttatccaa tccttccaag cttcatcatg acaatttaaa gcttcacatt
     3241 tctctacaat cacagactcc gattcagacc aaagtttatt ccaccatgta attgaatgga
     3301 agttcatatt atcttgccaa aatggaatga gttcatctgg tatacaatcc acgaaatctt
     3361 cttttaatcc aggcattgcc atagcaagta ttcctccctc ttttacaaga ggtgatatat
     3421 gattgtctaa aaatccttct ttgtttccaa agtagtgata agaatcgata cttatcaccg
     3481 catcaaagaa accttctgca taaggtagtt catgtgcctc tgcctgtatt ggaaatattt
     3541 tatcatccaa tttaaactct ttaaatcttt tatagttttc agttggttct atccataaat
     3601 ctgttgcaaa tacagtagca tcaaattcct ttgctaaaaa tatcgaagat atacccttac
     3661 cacaacctaa gtctaaaata cgcattccct tttctagttt tatcttactt gttaattctt
     3721 ccaatatttt tatacaatta ggtcccatca tatttttcat gagaaagtcc ttatcgtatt
     3781 tattactttt tgtaaatatc attctatctt tcctttccct atcagttatt atttattaaa
     3841 ttttatacgt ttgatttttt attttttata tgcttcttat attgagcaat ctctttttta
     3901 ttcattcttt aacagacaat tttaatgtgt aattttatcc actctgtgat agtaacttta
     3961 atgaataatc ttatctactg tgatagttaa ctttgatggg taattttatc tactccacag
     4021 caatcgcttt aatgagtaat cttatccact ctatgatagt tattttagtg agtaatttta
     4081 tctactctac agtaatcgct ttaatgagta atcttatcca ctctataata gtcactttaa
     4141 tgagtaatca taatttttat atcattttag atacttactc taataagaag tcattttcta
     4201 atacttaata agttttaatt acttccactt taacctatat actaattaac ttatttaatt
     4261 tagtgcatat ttgacacttt accttttatt ataccattta ttatcataaa tataataatt
     4321 ctattttttt aaaataaata tttataataa tctaaaataa atatttataa attctaatca
     4381 atcctaaata ataatctaaa atacatcaaa aaataaacta aaaaatatcg aaaaataatt
     4441 taaaagacat caaaactaaa tcttctaatc agcaattaaa agtctatttt cttagtttaa
     4501 aaaataaaga tagatttttt caaaacactg gataaatagg taaaaaaata aacagttagt
     4561 aaaataaatt tttactaact gtttattttt attgtttaat atgtcctata aatcctctaa
     4621 gtaatatttt ccttgcaaaa attctgattc taaacctaga tttttaaaat aatcgaccat
     4681 gcccatacac gcaaattttt ctgtagaata atgagtagca cctataacat taattaaatt
     4741 atcttttgct atttgatgaa actctaatac tggttcaaaa tgttttaaag gcttagtaaa
     4801 cccagtaata tatagattta taccaagttc agcaacttct cttgctacaa atggataact
     4861 tcctccccct gctgcaatag caactaaacc atcttttaat acagaatctc cataatcata
     4921 caatttcaca tcatgaccaa cagatttttt aattaattcc ttaatctctt ctattgattt
     4981 tagtgatgtt ttacatataa ctcctacctc aattttatcg tcatatttac aaaatggttt
     5041 gactatttct aaacccatag cttttgcaaa actaacagaa gttgaatagt cactatagtt
     5101 gtctagtgga gaatgtaata cataaaaaga aattctacga tttttcatct cttccatata
     5161 agatagtggt atgtcgtgaa atggaaaacc ttcatctgat gctatgtatc ccattgcatg
     5221 atgtgaaaaa attaaaatat ctttttcatc tttatctata acctgcttaa ttatttcttt
     5281 atcaggaaaa gtagttgtgt atactttatt aatattttga gcattatcta atactaatcc
     5341 tatgtatttt tttctaaatt ctgaagtgat aaaatcattt tcaaaattca taaaactcca
     5401 atcatcatta atatttttaa tattaaattc taaatctaat tttttataaa gttcaattgc
     5461 cttaataata accactcctt tataataata ttgaattact acatattaat atagaaattt
     5521 cacgataata aactttatac gtttaagtat tcctacttaa aattaa
//
LOCUS       DAMJXI010000132         5546 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.139, whole genome shotgun sequence.
ACCESSION   DAMJXI010000132 DAMJXI010000000
VERSION     DAMJXI010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5546
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.139"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(1..125)
                     /locus_tag="PC465_003641"
                     /pseudo
     CDS             complement(1..125)
                     /locus_tag="PC465_003641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
     gene            complement(792..1958)
                     /locus_tag="PC465_003642"
     CDS             complement(792..1958)
                     /locus_tag="PC465_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008790768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF2650909.1"
                     /translation="MNDMKFIETLKQKRKDCDYSQSRLAQELQISRQNLNEIENGKTK
                     ASKEMKHILLHYLDYCNCTQPFTLTIDYLRVRFLTTDALEIIKNVLAMKSEYFIHEDY
                     GMYGYEEQYVYGDISVNASKDSSMGVLLELRGMGCRNLEYVLQARGIDWYYFLRCCID
                     YQGVFKRIDLAVNDMGGLLDIEILRERYYANKVWKRSRTHEAVDSGKLSGTHGDTAKT
                     FYIGSKNSSIYFCLYEKEKEQKSKGIKTNIKNRFEIRLKNGKAEQTIEQLVFTRNPEQ
                     TIASLILTQIDFPDYILWDIFLDNVTTSLPFIMTPVAVNMEKTKRWLERQVMPSLLMI
                     KEIEKKTGANYLEEIDRHTRLTEKQELKIKQMTTDIADMIEKDTAVPQGNDGIF"
     gene            complement(2341..2871)
                     /locus_tag="PC465_003643"
     CDS             complement(2341..2871)
                     /locus_tag="PC465_003643"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650910.1"
                     /translation="MEKILENTLLLMILPWIFVWGILCILEKRKRKNEDGNKDEKSYV
                     IQNDNMFFPFFSLGMFLFSFCLFYTVFFTEFDISEVISVSVFVIFFAILTLDSAIWRV
                     IVDGDIIKYRSFYGITRTYNFNDITKGVYTKKGSLKIYIEGKRIFTFYDNLEFSLFEN
                     QMRKRKIPLEYKRKEK"
     gene            complement(3302..3613)
                     /locus_tag="PC465_003644"
     CDS             complement(3302..3613)
                     /locus_tag="PC465_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF2650911.1"
                     /translation="MIRNPYLPLTETTFYILLVLTAPAHGYAIIQEIDKLSEGSVKVA
                     AGTMYGAIENLLKLNWIEEIPSREKRRRVYKITDLGEEVLRLEIDRLGSLIKLSSDFG
                     Y"
     gene            4171..5343
                     /locus_tag="PC465_003645"
     CDS             4171..5343
                     /locus_tag="PC465_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HDF2650912.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT         1770 a         1062 c          824 g         1890 t
ORIGIN      
        1 aacaatcttt gtttttcctc tgttgccaat gccacgctta ttatttgtct tttcctgcct
       61 tgtttttaca atatcagcaa taacacatac cccctttctg taaaaatctt ttctaagcaa
      121 ttcaacggct tttgtcatag cccacaggag ttccacctct gcatagttct tatgtagccg
      181 tacccattgc gtgcgacgct ctgaacgctc aagctgtggc tgtacgggag tatcattatc
      241 agacaggaca ggtcatggcg ataaaagaga acaaatcttt tacaggaaca caaataagtt
      301 gtcgctcgct tttgcagggg aaaggtcatg gcgtatctgt ttcaacggct cgctgtctgt
      361 caaacgtatt gaactgcttt attcagttgt caaagaacat gaaagaagaa aatcgtcttt
      421 cctatatacc gcgttggaaa agagcagaag cgtaaccaat cttcaaaact tttctctttt
      481 cctgcaccat atagggaaag aaagtgtcat tctgctaagt tggtgatgaa aaaatctgat
      541 tttcttttca caccctaact acccatgcaa cactattact accaactatg gaatgaaaga
      601 ttttctttgc tccatatagg gaatggaaac tacggattgt taagttgaaa ttgaaaatcg
      661 tttcttcttt cacatcatat agggacagca accaccgatt taatgacctg ttttcaaaaa
      721 aagtcagatt tcctttcctt gcaccatatc tgtacgcaag taaccgtttt gttgcagatt
      781 ttttgaagaa attaaaaaat accgtcattc ccttgtggaa cagcggtatc tttctcaatc
      841 atatctgcta tgtctgttgt catttgttta atttttaatt cctgcttttc tgttagtctt
      901 gtatgtctgt cgatttcttc cagataattt gctcctgttt tcttttcaat ctcttttatc
      961 atcaataaag agggcatgac ctgtctttct aaccagcgtt ttgttttctc catattgaca
     1021 gcaacaggcg tcataataaa cggaagtgag gtcgttacat tatctaaaaa tatatcccat
     1081 aaaatataat cgggaaaatc tatctgtgtg aggataaggc ttgctatggt ctgttcggga
     1141 tttcttgtaa aaacaagttg ttctatcgtt tgttctgctt ttccattttt taaacgaatt
     1201 tcaaagcggt tcttaatgtt tgtttttata cctttgcttt tttgttcctt ttctttttca
     1261 tacaggcaaa agtagatgga actattcttt gaaccgatat aaaaggtttt tgcagtatct
     1321 ccatgtgtac ccgataattt cccgctgtct actgcttcat gggttcttga acgtttccat
     1381 accttgttgg cataatagcg ttcccttaga atttctatat ccagcagtcc gcccatatca
     1441 ttgaccgcta aatctatgcg tttaaaaaca ccttgataat ctatacaaca tcttaaaaag
     1501 taataccagt ctatccctct tgcctgtaaa acatattcca agttccgaca ccccatacct
     1561 cttaattcca ataaaacacc catagaacta tctttagaag catttacact aatatcccca
     1621 tagacatact gttcttcata gccatacatt ccgtaatctt catggataaa atattcgctc
     1681 ttcattgcca gtacattttt tataatttcc aatgcgtctg tggtgagaaa acgaacacgc
     1741 aggtagtcaa tcgttaaagt gaaaggctga gtacaattac aataatcaag ataatgtaga
     1801 agtatatgtt tcatttcttt actggctttt gtttttccgt tttcaatttc atttaagttc
     1861 tgcctgctga tttgcaattc ctgtgccagt cgtgattgcg aataatcaca gtcttttctc
     1921 ttttgcttta atgtttcaat aaatttcata tcattcatgc tttattcctc caatcaaaaa
     1981 aggcatatac tcatagaagc atacgccttg tatcttatca ttatttgcta ttgatatgct
     2041 gttttagacc tgtcggatcg aaaaaatagg atgtgaagtg aaataagttc ttataacctt
     2101 gtaaatcgtt gcatatcagc agttttgtat ttgtttttgc tcttgtcttt tgtaatagta
     2161 cccccctgtt agataacgag ggcttaatct tcgctcgcca caggctcgct cacagacgaa
     2221 gtgaaccagc cacttgcaag acatggcaga aaaatctgaa agatttccct gccaccgtgt
     2281 ctggatcact ccgtctttaa agtggtaata ttattaaact aattctgaac aatttcctta
     2341 ttatttttct ttgcgtttat attctaaagg aatttttctt tttctcattt gattttcaaa
     2401 taaagaaaat tctaaattat cataaaatgt aaaaattctt ttcccctcaa tatatatttt
     2461 taaagaacct ttcttagtat aaactccttt ggtaatatca ttaaaattat atgtcctagt
     2521 aatcccataa aatgaacggt atttgattat atcaccatct acaattactc tccagattgc
     2581 actatctaat gttaaaatag caaaaaatat gacaaagaca gaaactgata ttacttccga
     2641 tatatcaaat tcagtaaaaa acaccgtata aaaaaggcaa aatgaaaata aaaacatacc
     2701 taacgaaaaa aagggaaaga acatattatc attttgtata acatagcttt tttcatcttt
     2761 atttccgtct tcatttttcc gttttctctt ttctaagata catagtattc cccagacaaa
     2821 tatccaaggc agtatcatga gtaataatgt gttttctaat atcttttcca tatatctctc
     2881 cacgttttcc aaaattgata aatatattat agcacttacc tcatttcagt tcattacttt
     2941 tctgctatct gtcagaatat tttttatccc atgccttatc aagagtgcaa gcattgctta
     3001 cgcaacaagc tcttgacaat tcatgctcta aaaaatgata gataatcaag cagaaaaaag
     3061 aacaaattat gctgtgttac agcaacaaaa agacatctca tatcttgtat gaaatacctt
     3121 ttttcttttt tatgcgattt ttctttatcg tatcaaggtt ctttcaatcg tagtaaatta
     3181 gtggtaaatt tcttttgtat tttcattcct attacttaaa gtacttgtgt ttatgcagat
     3241 aatcagattt ttaatctttt tttataatag aaaattctaa attttttcat gttatcccct
     3301 cctaatatcc aaaatcagaa gatagcttaa tcaaacttcc tagacgatct atttctagtc
     3361 ttaaaacttc ttctcccaga tcagtaattt tgtaaactct tcttcttttt tccctacttg
     3421 gaatttcttc tatccaatta agtttaagta aattttcaat cgctccgtac atagttccag
     3481 cagctacctt aactgatccc tcacttaact tatcaatttc ttgaataata gcatatccat
     3541 gagcaggtgc agttaaaact aacagaatat aaaaagttgt ttcagttaaa ggtaaatatg
     3601 gatttctaat catataaaga cactcctctt aatatacagt cctattgtat aaagtgttac
     3661 tatatacata gtaactgtat acataaaaaa agtcaagtat tagaaaaaag ttcaaaagat
     3721 caagtgtgcg cttcgctccc actcccctcg acgttttagt agcctttccc tcacttcgtt
     3781 cagtccaagc caactaaaag ttttcgggat acattctcct tctcttccta ataatcaatt
     3841 aaaattttaa tctttatatt tctgctaatc actcaggaaa cagtacagaa aaacaaacac
     3901 gtatcataga tataaatgta atggcatagt gcgggtttta ttttcagcct gtatcatagc
     3961 taaacaaatc gagttgtgtg tccgtttttg ggcgttctgc tagcttgttt aaagtctctt
     4021 gaatgaatgt atgttctaag tcaaaaaact ctgacagcgc ctttatatag ataaagtccg
     4081 tataattgtg taaaagtaaa aaggccatat aacagtcctt ttacggtaca atgtttttaa
     4141 cgacaaaaac atacccagga ggacttttac atgacccaag tacattttac actgaaaagc
     4201 gaagagattc aaagcattat tgaatattct gtaaaggatg acgtttctaa aaatatttta
     4261 acaacggtat ttaatcaact aatggaaaat caacgaacag aatatattca agcaaaagaa
     4321 tatgaacgaa cagaaaaccg acaaagtcaa cgaaatggct attatgagcg cagctttacg
     4381 acacgtgtag gcacgctaga attaaaagta cccagaacac gtgatggcca tttttcaccc
     4441 acagtgtttg aacgttatca acgaaacgaa aaagccctca tggcttcaat gttggaaatg
     4501 tatgtatcag gcgtttcaac tcgtaaagta tcaaaaattg tggaagaact ttgtggtaaa
     4561 tccgtctcta agtccttcgt ttctagctta acagaacagc tagaacctat ggttaacgag
     4621 tggcagaatc gtttattatc agaaaaaaat tatccttact taatgaccga tgtactctat
     4681 ataaaagtac gagaagaaaa tcgagtactc tcaaaaagct gtcatatagc gattggaata
     4741 accaaagatg gcgaccgtga aattatcggc ttcatgattc aaagtggcga aagcgaagag
     4801 acctggacaa cattttttga atacctaaaa gaacgcggtt tacaaggtac ggaactcgtt
     4861 atttctgatg cgcacaaagg attagtctct gccattagaa aatccttcac caacgtaagt
     4921 tggcaaagat gccaagttca cttcctaaga aatatcttta ccaccattcc taaaaaaaat
     4981 tcaaaatctt tcagagaagc tgttaaagga atttttaagt tcacagatat taacttagcg
     5041 cgtgaggcta aaaatcgatt gattcatgat tatatcgatc aaccaaaata ttcaaaagct
     5101 tgcgcatcat tggatgatgg attcgaagac gcctttcaat ataccgtaca aggaaattcc
     5161 cacaatcgac taaagagtac caatctaatt gaacgactga atcaagaagt acgcagaaga
     5221 gaaaagatta ttcgcatctt ccccaatcaa acatcagcca atcgcttaat tggagccgtt
     5281 cttatggacc tacatgatga atggatttat tcttcaagaa aatacatcaa ttttgataag
     5341 tagaaatggt aaaaacattg tatagcattt tacacaggag tctggacttg actcacttcc
     5401 tttattattt ttcatttttt taaactattt aatactaatg tcttttataa tagcttttca
     5461 tatattatat aatcaatctt tataagtcct tttataaatt tcttttctac cattttcgat
     5521 aaattcctgt ttaatatttt taattc
//
LOCUS       DAMJXI010000133         5518 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.140, whole genome shotgun sequence.
ACCESSION   DAMJXI010000133 DAMJXI010000000
VERSION     DAMJXI010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5518
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.140"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            <1..107
                     /locus_tag="PC465_003646"
     CDS             <1..107
                     /locus_tag="PC465_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2650913.1"
                     /translation="EWICPSCNETHDRDINASINILKEGLRLITIQNK"
     gene            234..1136
                     /locus_tag="PC465_003647"
     CDS             234..1136
                     /locus_tag="PC465_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HDF2650914.1"
                     /translation="MLPQDYYGLIVILGVILGVMGAFYNWFTLYVQSLYKKIPKIGTF
                     GKLLIPFIMAGILGIVMPDVLGSGHNLVEELTSHEYIFGMVVLIFVIRFIFSAVSFGS
                     GAPGGIFFPLLVLGAFIGGIFGMVGVKVFGMNPDYVNNFVLLAMAGYFTAIVRAPLTG
                     IILIFEMTGSVSQMLSLSVISIVAYIVATLMKSKPIYESLLERLLEKNGEPVHKERGE
                     KILDQFSVMFGSPVANKAIQDVQWPENCLLVAIQRGGEEIIPRGKTILRPSDVIVTMT
                     DERDSGAVYDKMENLCKEHTAHIF"
     gene            1748..2761
                     /locus_tag="PC465_003648"
     CDS             1748..2761
                     /locus_tag="PC465_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HDF2650915.1"
                     /translation="MVSSFLNDIFRTILVSCIFIVILLVFRITLFKIFSKKFNYYIWL
                     IVIIKLSLPFMNYTFIFNESKYNGNINKISLGNFNSISIVYSTVLVSVWIAITIFYLV
                     YTLLKYIKLKNMINDLSYDVEDDKIKNLYENLLKELKINKKIRLKYSYEVESPVFFNS
                     CVILPPCDYTLKELNWIFRHELMHFKSKDLYIKYLVIFLKCVYWFNPFVYIMEKFIDL
                     DCEFYCDERVLKNCTIEEKQDYALTIISAMRKGSNSSNKFVAGLHKESDIKKRVFSMF
                     NEKYRNGILIAVILCLLSSITYFKIDLITTKSIFYPLSKQTPIENRTNSKPTYQINVY
                     IDN"
     gene            3113..3682
                     /locus_tag="PC465_003649"
     CDS             3113..3682
                     /locus_tag="PC465_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HDF2650916.1"
                     /translation="MKKKLEDMTLEELWNLFPIFLTTHKECWKNWFKEEQYRLTGILP
                     MQKIVRISHIGSTSVSTIYAKPIVDILIEIIPDYNMKDIKDLIESNGYICMSESSSRL
                     SLNKGYTVDGFEERVFHLHIRYVGDNDELFFRDYLIDHPDVAKEYEKLKLDLWKKYEH
                     NRDAYTDSKLDFVREFTEKAKVLYSNRYN"
     gene            complement(4018..5355)
                     /locus_tag="PC465_003650"
     CDS             complement(4018..5355)
                     /locus_tag="PC465_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2650917.1"
                     /translation="MGIYSLISTSINFILILINIFIAFFLYKLTSYFIDFRNHWIFKI
                     ILILGYSIISQMIIWLSDPVNILFTLFGYFILLIICSKSKLIPIISVVMILYPIIIGL
                     NFLFINNPIYEELIHSKEYILILSIVQIISALIKLLFWFLIHIFLKNRLVNIKQYLSN
                     KIWIFIDMVCISSFLSILIAIILPPTNLIPMGSNKNIILGNLPYGTYLIILSAILANI
                     GVILLLQPLIENVKMKIEKQANHLKEKYYNLLENQQIQIRKMRHDMNNHFQMIESYLE
                     IEDIAGAKKYFNQLKIGIGTLSGKQFCKNQALNSILNLRHTSLEENGVDVHFNIDIDN
                     HLGIEPIDLCTIFSNSLDNAIEASLKIPDLSNRKVVLKARCEKEYFSYLLTNNKVNPI
                     NRKQELFISDKKDSNSHGYGIENIREIVNKYNGKLDISYTESEFSLFLYIRLF"
BASE COUNT         2047 a          549 c          912 g         2010 t
ORIGIN      
        1 gagaatggat ttgtcctagt tgtaatgaaa ctcacgatag agatataaat gcaagtataa
       61 atatattaaa agaaggatta agactaataa caattcaaaa taaataactt atgtaagaac
      121 cgtaggaact acggggatag cctgtggaga attagtaaga catatgttag tatgcaaaat
      181 tctatgaagc aggaaccctg tgactttagt catgggaggt tcagattgga aatgtgttgc
      241 cacaagatta ttatggatta atagtgattt taggtgttat tcttggagtt atgggggcat
      301 tttacaactg gtttactcta tatgtgcagt ctttatacaa gaagattcct aaaattggta
      361 cctttggaaa actgttgatt ccatttataa tggctggtat tcttgggatt gttatgcctg
      421 atgttctggg gagtggacac aatttagttg aagaacttac aagtcatgaa tatatttttg
      481 gaatggttgt tttgattttt gttatacgtt ttatattttc ggctgttagt tttgggtcag
      541 gtgcaccagg gggaatattt tttccattgc ttgttttagg agcatttata ggtggaatat
      601 ttggtatggt aggtgttaaa gtttttggaa tgaatcccga ttatgtaaat aactttgtgc
      661 ttttggctat ggcaggatat tttacagcta ttgtgcgtgc ccctttgact ggtatcatat
      721 taatttttga aatgacaggt tctgttagtc aaatgctttc actatcagta atttcaattg
      781 tggcatatat tgtggctaca cttatgaagt ctaaacctat ttatgaaagt cttcttgaga
      841 ggttacttga aaaaaatgga gaacctgtac ataaagagag gggcgaaaag atactagacc
      901 agttctctgt tatgtttggc tctcctgttg cgaacaaggc aattcaggat gtacagtggc
      961 ctgaaaattg tcttttggta gcaattcaaa gaggtggaga agaaattatt cctaggggta
     1021 agacaattct tagaccaagt gatgtaattg tgactatgac agatgagaga gatagtggtg
     1081 ctgtgtatga taaaatggaa aatttgtgta aagaacatac ggcacatatt ttttagggat
     1141 aatgatgaat gtttaataat gatagaatat ttaatgaaga tttgattaaa aaattggtaa
     1201 tttgaaagag agttaaggaa ttaatataag aaaatgaaaa tgtgatatct tagatgtaaa
     1261 agagtttgaa gaaaataatt gtatatattt gttaatgaga ttatatggac taatggtata
     1321 tttatactgt gctaaaagtt gcactattgt atgaggaatg ggaataaagg gtttgaaaaa
     1381 ataggtagaa gatttttcag atattcttat tgggatattt taattaatat attttaattg
     1441 cgatattttg ggaagaatag aatttattta taaatgaaaa taattaaaag gggttaaggt
     1501 tgtattagcc ccttttgctt atagagtttg gaaatggtat cttgatagta gttgtttcat
     1561 gcttattata ttttattaca tattttaaaa ttgaccttat tactcctaaa tcattgttat
     1621 atcaactttt aaaacacttt caagacaatc gcctattgaa aacaaagtta attaaaaacc
     1681 tacatatcag tttagtattc gtgtagatga ttatataaat ataaaagtat aagaaaggtg
     1741 agtatctgtg gttagttcat ttttaaatga tatctttaga acaattttag taagttgtat
     1801 ttttatagtt attttattag tctttagaat aactttattt aagattttca gtaaaaaatt
     1861 taattactat atatggctta ttgtgattat taagctatca ttaccattta tgaattatac
     1921 ttttatattt aatgagtcaa aatataatgg taatattaat aagataagtt taggcaattt
     1981 taatagtatt tctattgtat atagtactgt tttagtctct gtttggattg ctattacgat
     2041 attttattta gtttatactt tattgaaata tattaagctt aaaaatatga taaatgattt
     2101 gtcttatgat gttgaggatg ataagataaa aaatctttat gaaaatttat taaaagagct
     2161 taagataaat aaaaaaatac ggcttaaata ttcatatgaa gttgaaagtc cagtattttt
     2221 taattcgtgt gtcattttac caccatgtga ttatacattg aaagagttaa actggatatt
     2281 taggcatgag ttgatgcatt ttaagagtaa agacctttat attaagtatt tggtgatatt
     2341 tttaaaatgt gtttattggt ttaatccttt tgtgtatata atggagaagt ttatagattt
     2401 ggattgtgaa ttttattgtg atgaaagagt tttgaagaat tgtacgatag aagagaagca
     2461 ggattatgca ttgacaataa ttagtgcaat gagaaaaggt tcaaatagtt caaataaatt
     2521 tgtggctgga ttacataagg agtcagatat taaaaaaaga gtgtttagta tgtttaatga
     2581 aaagtacaga aatggtattt tgatagcagt tattttatgt ttattatctt ctattacata
     2641 ttttaaaatt gatttaatta ctactaaatc aatattttat ccactttcaa aacaaacacc
     2701 tattgaaaac agaactaatt caaaacctac atatcagatt aatgtttata tagataatta
     2761 aaaaatacaa agtttaacaa gagattaata taaataattt taataagtat ctttcacata
     2821 tgttaaattt actttaatta tattaaagcc aatgaattat tctttagaag ctccaatgcc
     2881 agtaaataca ggtaaagaaa aaattactac aattgtagat taaaaatgtt ctaatattta
     2941 aaaaaatgca aaagtgtaag aagggtaaaa atctattata atacattaaa aactaaattt
     3001 agaaaaattt acataattag aaaaatgatt tgataaaaaa taaagttaaa tattaactaa
     3061 gtaaatttga aaaagaaaaa atataaagta caaatttaaa aggaggtaac taatgaaaaa
     3121 gaagttggaa gatatgactt tagaggagtt atggaacttg tttcctatat ttttgactac
     3181 tcacaaagaa tgttggaaaa attggtttaa agaagaacaa tatagactaa ctggaatatt
     3241 gccaatgcaa aaaattgtta gaataagtca tattggaagt acttctgtga gtacgattta
     3301 tgccaagccc attgttgaca tactgattga gataattcct gattataata tgaaagatat
     3361 taaagatttg attgagtcga atggatatat ttgtatgtct gagagcagta gtaggctttc
     3421 acttaataaa gggtatacag tagatggatt tgaagaacga gtttttcatt tgcatataag
     3481 gtatgtaggt gataatgatg agttgttttt tagagattac ttaattgacc acccagatgt
     3541 tgcaaaggag tatgaaaaac ttaagttgga cctttggaag aagtatgagc ataatcgtga
     3601 tgcttataca gatagtaaac tagattttgt tagggagttt actgaaaagg caaaggtgtt
     3661 gtattctaat agatataatt agaaataggt acaattagat atttatctta tatattgtat
     3721 tatatttttt aagaaagtaa ttaatagaaa aagggcttgt ttcaaaatgg agagataaat
     3781 ccctttttca ttgttgaaag gataaaaata tatttgattt catgtaaaaa agagtgcctc
     3841 atcaactaaa aagtttattt tgagacacac acatttttac taaggtaaat aaaatatcac
     3901 atttgattaa attttaagtt aatgaatata tgtgtaaata tttaattata agttattata
     3961 attttacata gtatcaaaca atctaatttg tattatataa gataatctaa ttttagacta
     4021 aaataatcta atataaagaa ataaagaaaa ttcactctca gtataagaga tatccaattt
     4081 tccattgtac ttattaacaa tttctctaat attctcaata ccatatccgt gagaattact
     4141 atctttttta tctgaaataa atagttcttg ttttctattg ataggattta ccttgttgtt
     4201 tgtcaataaa tagctaaaat actccttctc acaacgtgcc tttaatacca cttttctatt
     4261 tgacaaatca ggaattttca aagatgcttc tatagcgtta tctaaagaat ttgaaaaaat
     4321 agtacataaa tctataggtt ctatacccaa gtgattgtct atatctatat taaagtgcac
     4381 atcaacacca ttttcttcta aacttgtatg acgaagattt aaaattgagt taagagcttg
     4441 gtttttgcaa aattgttttc cactaagagt acctatacct atttttaact gattaaaata
     4501 ctttttagct ccagcaatat cttcaatttc taaatacgat tcaatcattt gaaagtgatt
     4561 attcatatca tgtcgcattt tgcgtatttg aatttgttga ttttctagta agttatagta
     4621 tttttctttt aggtgatttg cttgtttttc tatcttcatc tttacatttt caatcaatgg
     4681 ctgtaaaaga agtatcacac cgatatttgc cagaattgct gacaagatga ttagataagt
     4741 gccataaggt aagttgccta agataatatt cttattacta cccataggga ttaaattagt
     4801 aggtggcaga ataatagcaa ttaatattga taaaaatgaa gatatacata ccatatcaat
     4861 aaaaatccat attttatttg ataagtattg ttttatattg accaatctat tctttaggaa
     4921 aatatgtatt aaaaaccaaa ataataattt aattagagca gaaattatct ggactattga
     4981 aagtattaaa atatactctt ttgagtgtat aagttcctca tatatagggt tgtttataaa
     5041 aagaaaatta agcccaatta taataggata aagtatcatg acaactgata ttataggaat
     5101 taatttgctt ttgctacata ttataagtag tataaaatat ccaaatagtg taaacaaaat
     5161 atttacgggg tcggaaagcc atattatcat ttgactaata atagagtagc ccaaaatcaa
     5221 tatgattttg aaaatccaat gattcctaaa gtctataaaa taggaagtca acttataaag
     5281 aaaaaaggct atgaaaatat tgattaatat tagaataaaa tttatgcttg tagagattaa
     5341 agaataaatg cccatttaat atacctttct attaattaag attctggaaa ctaagtttta
     5401 aaaaattaaa tcttaaaaat taaaattctg gaaattagat ttcaaagaat tgattttgaa
     5461 aaataaaatt ctagaaatta agcttcaaaa aattgagttt taaaagattg aaatttta
//
LOCUS       DAMJXI010000134         5445 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.141, whole genome shotgun sequence.
ACCESSION   DAMJXI010000134 DAMJXI010000000
VERSION     DAMJXI010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5445
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.141"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(204..1388)
                     /locus_tag="PC465_003651"
     CDS             complement(204..1388)
                     /locus_tag="PC465_003651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2650918.1"
                     /translation="MLSKRLNFITPSYTIGISSKVKEMESNGVKVINLSIGEPDFNVP
                     NNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSI
                     TNTLLALTDEGDEVLLPKPYWVSYPEMIKLVNAVPVFIDTKKENGFKLTKEELEKSIT
                     DKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIAS
                     LSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIA
                     YGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFE
                     YKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKI
                     MA"
     gene            1761..4112
                     /locus_tag="PC465_003652"
     CDS             1761..4112
                     /locus_tag="PC465_003652"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HDF2650919.1"
                     /translation="MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLS
                     EQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNS
                     KTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
                     SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAA
                     IAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNI
                     VYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKT
                     YQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETP
                     IFPILIFKVKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPD
                     TEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEE
                     LDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDNLGPEDTLKEVIKQGTLT
                     IGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATDKYKLNFSLMGTPAE
                     GLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGH
                     ITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVC
                     GRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR"
     gene            4134..4673
                     /gene="nrdG"
                     /locus_tag="PC465_003653"
     CDS             4134..4673
                     /gene="nrdG"
                     /locus_tag="PC465_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HDF2650920.1"
                     /translation="MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDL
                     CGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEEIAREAKINGLDVWSYTGF
                     TFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLK
                     YKKVFLVEQYMKDDLSIAE"
BASE COUNT         2136 a          613 c          866 g         1830 t
ORIGIN      
        1 ttataataaa tttagaattt aacttatata gtttaatttg ataatttgat gaaaaaaata
       61 aaagacttac tgatttttaa atctataggt cttttatttt ttatctaaca tttaaattaa
      121 gttgttgaat atatcttata ttacttacct tatatattaa ttaccattaa tacattatat
      181 ctaattacta ttcatctaaa ttactatgcc attattttat atacaaattc ttttaattta
      241 tctaatccag ataagaaagt attttcactg caagcatagg atatacgaat atatttatcc
      301 ataccaaatg ctatgccagg aacaactgca acattatatt cttctaaaaa ttgattacaa
      361 aattctatag aaaaactatc tttatattca aatttctcag atactttaga aagatctata
      421 aatatataga atgcgccatt tggattcaca tatcctacat tatcaataga gtctagtttt
      481 gatttaatta aatctcttct tgatttatat gttttaacca tattgtctat gtcaattgag
      541 caatctttca aggctccata ggctatgtat tgtgctgtta gacttgggtg agatataaga
      601 tgtccttgta tagaactcat tgctttagca atcgttttat tagatgcagt atatcctaat
      661 cttaatccag tcattgcagc tgacttagaa aaaccattta tagttattgt tatatcttta
      721 gcttcttcgc ttaatgatgc aattgatgta aattcaccag tgtagcatat tttttcatat
      781 atttcatctg ctaaaatata tattttattt tgtatgcata catctactat ttctattaat
      841 tcatcttttg tataaacact accagtagga tttgaaggat tgtttattac aagaattttt
      901 gttttatctg ttatagattt ttcaagttct tcttttgtta acttaaatcc attttctttt
      961 ttagtatcaa taaaaactgg aacagcatta actaacttaa tcatttcagg ataactaacc
     1021 caataaggct ttggtaataa gacttcatct ccttcgtctg ttaaagctag taaagtattt
     1081 gttattgagt tttttgctcc acttgataca actatttcgt ctattgaata gttacagtta
     1141 ttttcttcaa taagtttttt acagatttcc tctctaagta tttttaatcc tggaactaaa
     1201 tcatatttag tgtaatcttt atttaaagaa tcaataccat aagattttgc gttattaggt
     1261 acattaaaat cgggttctcc tatactaaga tttattactt taactccatt actttccatt
     1321 tctttaactt tagaactaat acctattgtg taggatggtg ttataaagtt tagtcttttt
     1381 gataacataa aatgcctcct tttaaattat tatttatatt atacgacaaa tttaaagaat
     1441 ttacataagg aaatttgtag atatatacat taatatatat aatagcctac actttttgcc
     1501 taaaattagt gtaaaaaaaa gagaaaaaaa ttttaacttt caaagttgtt agaaacgctg
     1561 ctgttcaaaa tatccacata gtatttgcaa tgatttgcgc aagtttgact attatgtaca
     1621 aatttggtaa tcttaatata gcaattatta agataatccc tttaacttag ttgaagggga
     1681 tttttttaga cttaacatac tacatatagt ggtatgggga ttaataaaat acaatatata
     1741 gtaacaggag gtttttttaa ttggttgaat tcgtaaaaaa aagagatgga agagtaattc
     1801 catttaatga agatagaata acaagagcta tatttttagc agcaacgaat gttgcagaaa
     1861 gagaaggaat agtacctgat tataaattat ctgagcaatt aactcaagaa gtaataaagt
     1921 ttttaaatca taaatactca gaatcagttc caagtgttga agatatacaa gattctgtag
     1981 ttaaggttct tatagaaact ggccatgcaa aaactagtga agaatatata atatacagaa
     2041 ctgaaagaag tagaataaga aattcaaaaa caaggttgat gaaggcaata gaggaaatta
     2101 cctttgaaga tgcagaagat gctgatataa aaagagaaaa tgcaaatatt aatggtaata
     2161 cagcaatggg aactatgtta caatatggaa gcactgtatc taaagaattt tgtaaaacac
     2221 atatattaaa accagagcat tcttttgctc atgataatgg agatatacac atacatgata
     2281 tggatttttt aaatatggga acattaactt gttgtcaaat agatgttaaa aaactattca
     2341 atggtggatt ttcaacagga catggctttt taagagagcc acaagatata ataagttatg
     2401 gtgcattagc tgcaattgct atacaaagca atcaaaacga tcaacatgga ggtcaaagta
     2461 taccattttt cgattatgga ttggctgaag gtgtatataa gacatttaag aaattctaca
     2521 taggaaattt agctaaagca ttgaagttat ttaaaggaat tgaaaataat gatgtgataa
     2581 agaacatagt atataataca gagaaagaaa caaatcaaaa agttggtctt aagagagatg
     2641 aattgtatct aaacttagaa aaagagaaat taatacagac ttttgatata gatgatgaac
     2701 ttgtaaataa gatgcaaaac tttgcatttg aagaatcgta tagagaaact gataaaaaaa
     2761 catatcaatc tatggaagca tttatacaca atctaaacac aatgcactct agagcaggtg
     2821 cacaggtacc attttcaagt gtaaacttcg gaacagatac ttctgaagaa ggaagaatgg
     2881 taactaagaa tcttctatta tctcaagaaa gaggtttagg taatggagag acaccaattt
     2941 ttccaatttt aatatttaag gtcaaagaag gcataaattt aaatcctgaa gaccctaatt
     3001 atgatttatt taaattatca tgcagagtat cagctaaaag actattccct aattttagct
     3061 ttttagatgc gccttttaat gcaaaatatt ataaaaaagg tgaaccagat acagaggcta
     3121 catatatggg ttgtagaaca agagtactta gtaatgtgtg tggttcagaa acagttagtg
     3181 gtagaggaaa catatctttt actacagtaa atttaccaag attgggtata aaacatggta
     3241 ttataaataa tgaaaaggct aatttagatg gtttctttga agaattagat gagaagataa
     3301 acttaattat agaacaatta ttggagcgcc ttgaggttca aggaaataaa aagatgaaga
     3361 attttccatt cttaatgggg caaggtgtat ggaaaggttc tgataattta ggaccagaag
     3421 atacactaaa agaagtaata aaacaaggaa cattgacaat tggatttata ggtttagcag
     3481 agtgccttat tgctcttata ggtaaacatc atggagaaag taaagaagct caagaattag
     3541 gattaaaaat agtgtcacat atgagacata aaatggatga agcaacggac aaatataaat
     3601 taaatttctc cttaatgggt actccagcag aaggtctttc aggtaggttt actaaaatag
     3661 ataaaaaagt ttatggagaa attaaaggta tcacagataa agaatattat actaattcat
     3721 tccatgtacc agtttattac aatataagtg catatgataa aattgagata gaagctccat
     3781 accatgaatt gactaatgca ggtcatataa catatgtaga gttagatgga gatccatctg
     3841 ataatttaga agcttttgaa actgttataa aagctatgaa agatttgggt ataggatatg
     3901 gaagtataaa tcatcctgta gatagagacc caatatgcgg tttttcaggt gtaataacaa
     3961 gtaatatatg ccctgtatgt ggaagaaatg aagatgaaag tgacatcaaa ttcgaaagaa
     4021 taagaagaat aacaggatac ttagttggta cagttgatag atttaataat gctaaaaaag
     4081 cagaagtaag agatagagta aaacatagat agttttattt gggggaataa gttatgaaaa
     4141 taagaatgtc atctactata agttatgaca gcatagttga tggaccagga ttaagaatgg
     4201 taatatggac tcaaggatgt attcataatt gtaaagagtg ccataatcct cagacacatg
     4261 atttatgtgg aggattttat atggatacag aagaaattat aaataaagtc aaatcattga
     4321 aattacaaaa aggcattacg ctatcaggag gagaaccatt tttacaacca gaaccattag
     4381 aagaaatagc aagagaagct aaaataaatg ggttagatgt atggtcatat actggattta
     4441 cgtttgaaca actgttagat aaaaaaaata gagcgtattt taaaaattta aatttactaa
     4501 agcaaattga tattttagtg gatggaaaat ttatagctga aaaaaaagat ataagcttaa
     4561 agtttagagg gtcatcaaat caaaggataa ttgatgttca aaaaagtttg aaatataaaa
     4621 aagtgttttt ggttgagcaa tatatgaagg atgatttatc tatagcagaa taaaatataa
     4681 ataaacagga ttaaatatat gcatatattt aatcctgttt attttcatat aatatttcaa
     4741 gcttgtataa tgtaacaatt aaaccaaaag actcattgta tatttgaaat taagtttttt
     4801 atagtttata ggtgttttat gtggattacg aatgatatag tatcgataca ttatttaata
     4861 gattcttatg ccaagaaaca attaatttat agaaattctt aattgttaca atataaatat
     4921 ctagataagt tataagatac tgataaataa tttataaagt ttattaatct aatattgtgt
     4981 gtgaatatta agtggtcaag tagtctaaaa aatgaaaaag atttaaaaaa gtgttttaac
     5041 taaacacata agtgttaaat tcatgtataa gtataggtta gatacataag aaataattat
     5101 gtaatatcta tctttgtaaa aaaatattaa attttgtaat ttgtggataa atatgtttat
     5161 aatgtggata atatttaatg taataagtta aagcaatatg aatcaactgt ttataatgtg
     5221 gataatatta taaatgtatg aataattgca gtatttaaaa acaaaaaaag ttaaaaaagt
     5281 tgttgactct aaaagaaaaa gttggtatag taatacttgt cctcaagaaa agggcaaaca
     5341 aataaagcac aaagaacttt gaaaattaaa cagtaggtta atttataaaa caagaaacaa
     5401 accataaagc cagatatttt gataacaata gtatctgagc ctgat
//
LOCUS       DAMJXI010000135         5400 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.142, whole genome shotgun sequence.
ACCESSION   DAMJXI010000135 DAMJXI010000000
VERSION     DAMJXI010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5400
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.142"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            374..1900
                     /locus_tag="PC465_003654"
     CDS             374..1900
                     /locus_tag="PC465_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2650921.1"
                     /translation="MNESYWFLNSSPKEYNKLGENIKTDCLIVGGGITGLTTAYLLAK
                     EGKKVVLVEADKIGYGTSGRNTGKVTCQHDIFYSKIEKKYGLDKAKSYYNANNEALNL
                     VKQIIEENNIKCDFKRETSFVFTEKEDTIKNIKDEYRTCKKIGINCEYHETIENIPLD
                     IKGAISFTNQGQFNPKKYIDGLAKAAVNLGLKIYENTPVVDLEKGKICRVKTREDNII
                     EAENVIISSHSPWYDGLNFYFAKEYAERAYLMVAVLENKLADGMFISIDDPSITFRQY
                     NDGSENLLIFGGGDHKVGQGGTEKEIFDDLEHYGKEVFKVKDFKGKWSAQDNMSFDNV
                     PYIGYINKREDNIYVATGFSKWGITNGTAAGIIIKDLIINNNSDYKDTFNPSRLGSYF
                     SKDFIKENANVAINYVSGKLKIGSGDMPKNNGEGKIVNIDGKRYGVYKDDNGDFYIVD
                     TTCTHLGCELNFNSEEKTWDCPCHGSRFDYKGNILEGPALKPLKLYGHGDNDVNPKLL
                     "
     gene            1928..2485
                     /locus_tag="PC465_003655"
     CDS             1928..2485
                     /locus_tag="PC465_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650922.1"
                     /translation="MNKLLKPITILLYIVYILSAVFFVANKEYGSLGLVAISLVGTFI
                     LSFINKQTERLLSKELYIMLALFIMFSSLLGTCFNFYDINYYDDFLHLWSGIISCIVA
                     FSIIKYFYTQREISKMSKVFLVIFLFMFSMGVASLWEIGEFLMDTFVGTTTQAGGLED
                     TMIDMVDALIGTIITIPFIVKKSNI"
     gene            3007..4050
                     /locus_tag="PC465_003656"
     CDS             3007..4050
                     /locus_tag="PC465_003656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650923.1"
                     /translation="MLKKWFGIVKKRQKSESVKEEGEVILKNEKILSEEKLIDEEGVV
                     VNIDNEILTKVEVVNDDNEIEEKIIEEDWLISENTIKLDDKEAIINDKNIELCKKEVQ
                     VEGEKIDLNKFEGLDQNENYNLEKNVIEEKEVSECLTEEDLEYIKEIKIKRGKSIKAI
                     NLYTKEEWVFDTHIQCSKKLKVPLGYIRENLKYGYMDYFGDAINYLSEVLNIDEYCKS
                     EWSYLDNSKSPSEIFNILNNKIFSIRLSNEKRNEILTNDKIEALKMNYRFECIDEEYD
                     EYFKKYKSIIKRGGKKKVELVNKKGDILEIFKSLEECAIYLQKEKNEVIQMLKYGDTK
                     VGRNFIRYSLRSI"
     gene            4161..5303
                     /locus_tag="PC465_003657"
     CDS             4161..5303
                     /locus_tag="PC465_003657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2650924.1"
                     /translation="MSEEKNPKENTLDESKNSDNVNSKKDDVSDEKNTDNKVKKREIK
                     LNNKTLKAIVAIVAVGAICLGGGYIFGKEAGRKLPATSKHYNSSEVVATIGDKKITGE
                     MLRKRMEPLFYLNAKTTMTDDEIRSYESNMIETMITSDILSSEAAKEKISITNDQLDA
                     QYNNLMSSIESAMGMTKEEFLKQFDLTEKYIKDDMKKELVASKYLNEKSKVTDKEAEN
                     YYNKNKSNYLQVRASHILIKTVDDKGKQVSSSKKAELKKEAEEILKKAQAGEDFATLA
                     KKYSEDSSAESGGDLGFFGKGQMVESFEKAAFALKKGEVSNKLVESDYGYHIIKKTDE
                     KYQPFEEVKSDLVSSLTSEKQNLLIQNLKEKYNVKITDKYQMKAKE"
BASE COUNT         2285 a          446 c          942 g         1727 t
ORIGIN      
        1 caattaattt atataaaata aatttttaag taaatatttt tatagagaga ttgctatatt
       61 acatatcaga aaaatattaa actaactaaa tcaataaaaa agttggtggc taacagttta
      121 taattgttag cacaacatca tcttatgtat tgaaatctaa aatatcctca tttttactta
      181 gcataaatac tattaattaa gaaaataata tagaaattat aaatatatat aagtttagtc
      241 tggtgtataa aacaagaaaa ctaagtgatt tttaatttag ctttttatta agcttatttt
      301 ttatactatt tataataaat aaactccatg atgggaaaac tattactatt taatatgtaa
      361 aggagtattt taaatgaatg aatcatattg gtttttaaac tcaagtccaa aagaatataa
      421 caaattaggt gaaaatataa aaacagattg tcttatagta ggtggtggaa taactggatt
      481 gacaactgca tatttattag caaaagaagg taaaaaagta gtgcttgttg aggctgataa
      541 aataggatat ggaacttctg gaaggaatac tggtaaggta acttgtcagc atgatatatt
      601 ttactctaag atagagaaaa aatatggatt agataaagca aaatcatatt ataatgcaaa
      661 taatgaagct ttaaatttag ttaaacaaat aatagaagaa aacaatataa aatgtgattt
      721 taaaagggaa acttcttttg tatttacaga aaaagaggat actataaaga atattaaaga
      781 tgaatatcgt acatgtaaaa aaataggaat aaattgtgag tatcatgaaa ctatagaaaa
      841 tattccatta gatataaagg gggctattag ttttactaat caaggtcaat ttaacccaaa
      901 gaagtatatt gatggattgg caaaagcagc agtaaattta gggctaaaaa tatatgaaaa
      961 tacaccagta gtagaccttg aaaaaggaaa aatatgtagg gttaaaacaa gagaagataa
     1021 tataatagaa gctgagaatg ttataatttc atctcatagt ccatggtatg atggattgaa
     1081 tttttatttt gcaaaagaat atgcagagcg tgcttattta atggttgcag ttttggaaaa
     1141 taaattagca gatggtatgt ttataagtat agatgaccca tcaataactt ttagacaata
     1201 taatgatgga agtgaaaatt tactgatttt tggaggagga gaccataaag ttggtcaggg
     1261 aggaactgag aaagaaatat ttgatgattt agagcattat ggtaaagaag tctttaaggt
     1321 aaaagatttt aaggggaaat ggtctgctca agataatatg agttttgaca atgttcctta
     1381 tattggttat atcaacaaaa gagaagacaa tatttatgta gctacagggt tctctaaatg
     1441 gggaattact aatggaactg ctgctggaat aataataaaa gatttaataa taaataataa
     1501 ttctgattat aaagatactt ttaatccatc cagactaggt agctactttt caaaagattt
     1561 tataaaggaa aatgcaaacg tagcaataaa ttatgtaagt ggaaaattaa aaataggtag
     1621 tggagatatg cctaaaaata atggagaagg aaagattgtt aatattgatg gaaaaagata
     1681 tggtgtatat aaggatgata atggagattt ttatattgta gacactacat gtactcattt
     1741 aggatgtgaa cttaatttta acagtgaaga aaaaacatgg gactgtccat gtcatggttc
     1801 tagatttgac tataagggaa atatacttga aggaccagct cttaagccat taaaacttta
     1861 tggacatggt gataatgatg ttaatcctaa gttattataa aattattttt aggaaggtaa
     1921 agtgtatatg aataaacttt taaagccaat aactatacta ttgtatatag tttatatttt
     1981 atctgccgta ttttttgtag caaacaaaga atatggaagt ctaggtctag tagcaattag
     2041 tttagttggt actttcattt tgagttttat aaataagcaa actgaaagat tattgagtaa
     2101 agaattatat ataatgcttg ctttatttat aatgttttca tcattgttag gtacttgttt
     2161 taatttttat gatataaatt attatgatga ttttttgcat ttatggtcag gtataatatc
     2221 ttgtattgtg gctttttcta taattaaata cttttataca caaagagaga taagtaaaat
     2281 gagtaaagtg tttttagtta tatttttatt tatgtttagt atgggagtag cgagtttatg
     2341 ggaaataggt gaatttttaa tggatacttt tgttgggact actacacagg ccggagggtt
     2401 agaagatact atgattgata tggtagatgc tttaataggt acaattataa ctattccttt
     2461 tatagtaaaa aaatctaata tatagtttta aattttttat attaattata atggatttaa
     2521 ttaatcatgt tgagtttcaa ggtctatatg attaattaaa tccatttttg ttatttataa
     2581 ttattattga atatattttt acatataaga tataaggtga tagatagaaa ttgttggatt
     2641 atgtaaataa ttaatatata ataccattat gggcaataaa tacaaatcaa atgataatat
     2701 agtctattta tgtaaatgtt aaattgtatc ctaagtataa tagtaagttt tttgatagtg
     2761 gtgtagaaag taaaaatcta ctagcctaaa ttgatgtatg gattagttta ggaacagtaa
     2821 ttgcatatct taagtttgat gtcatgttgg gctactagaa ataggtcatc tttttcactt
     2881 gaatatcttt tctttaaaca tggggagtat catatcaaaa acatatgaaa attaagtgat
     2941 ttatgagaac agtaatattt tatatgatag tatagaatag taataaagta ttaggaggaa
     3001 cattgagtgt taaaaaagtg gtttggtatt gtgaaaaaaa gacaaaaaag tgagtcagta
     3061 aaagaagaag gtgaagtaat attaaaaaac gaaaaaatat tatctgaaga aaagttgata
     3121 gatgaagaag gagttgtagt taatattgat aatgaaatat taactaaagt agaagtagta
     3181 aatgatgaca atgaaataga agaaaaaata atagaagaag attggttaat tagtgaaaat
     3241 accataaaat tagatgataa agaagcaatt attaatgata aaaacataga attatgtaaa
     3301 aaagaagttc aagttgaagg tgaaaaaata gatttaaata agtttgaagg acttgaccaa
     3361 aatgaaaatt ataatctaga aaaaaatgtt attgaagaaa aagaagtaag tgaatgtttg
     3421 acagaagaag atttagagta cataaaagaa attaaaataa aaagaggaaa aagtataaaa
     3481 gctataaact tgtatactaa agaagagtgg gtttttgaca ctcatataca gtgtagtaaa
     3541 aaactcaaag ttccattagg gtacataaga gaaaatttaa aatatggata tatggattac
     3601 tttggagatg caataaatta tttaagtgaa gtattaaata tagatgaata ctgcaaaagt
     3661 gaatggagct atctcgataa tagcaaatct ccatctgaga tatttaatat tctaaacaat
     3721 aaaatattta gtataaggct ttctaatgaa aaaagaaatg aaattttgac aaatgataaa
     3781 attgaagcat taaaaatgaa ttatagattt gaatgtattg atgaagaata tgatgaatat
     3841 tttaaaaaat ataagtctat aatcaaaaga ggtggaaaga aaaaagttga attagtaaat
     3901 aaaaaaggtg acattttaga aatatttaag tctttagaag aatgtgccat ttatttgcaa
     3961 aaggaaaaga atgaagttat acaaatgtta aaatatggag atacaaaagt aggaagaaac
     4021 tttataaggt atagtttgag aagtatttaa tttcatttta aattcataag agtttcattt
     4081 ctgattcaca catttaatat tattttaatg taaaataata aaggtgaagt attgtacaat
     4141 taaaattaag gagggtatta atgtctgaag aaaaaaatcc aaaagaaaat acattagatg
     4201 aatctaaaaa ttcagataat gtaaattcta aaaaagatga tgtgtcagat gaaaaaaata
     4261 ctgataacaa agttaaaaaa agggaaataa agctaaacaa caaaacactt aaagctattg
     4321 tagcaattgt tgcagtagga gctatatgtt taggtggagg ctatattttt ggcaaagaag
     4381 ctggaagaaa attgcctgct acttcaaaac actataatag cagtgaggta gtagctacta
     4441 ttggggataa aaaaataaca ggtgaaatgt taagaaagag aatggagcca ttattttatt
     4501 taaatgcaaa aactactatg actgatgacg aaatacgttc atatgaatca aatatgattg
     4561 aaactatgat tacatctgat atattatcct ctgaagcagc aaaagagaaa ataagtataa
     4621 ctaatgacca actagatgct cagtataata atttaatgag tagtatagaa tcagcaatgg
     4681 gaatgactaa agaagagttt ttaaaacagt ttgatttgac tgaaaaatat ataaaagatg
     4741 atatgaaaaa agagctagta gcatcaaaat atttaaatga aaaatcaaaa gttactgata
     4801 aagaagcaga gaactattac aataaaaaca agagcaatta tttacaagtt agagcttcac
     4861 atattttaat aaaaactgtt gatgataaag gtaagcaagt tagtagtagc aaaaaagctg
     4921 aacttaagaa agaagctgaa gaaatactta aaaaagccca agctggggaa gattttgcta
     4981 ctctagctaa aaaatactct gaagatagta gtgcagaatc aggtggagat ttaggtttct
     5041 ttggtaaagg tcagatggtg gaatcttttg aaaaagcagc ctttgcattg aagaagggag
     5101 aggtatctaa caaacttgta gaaagtgatt atggatatca tataattaag aaaactgatg
     5161 aaaaatatca gccatttgaa gaggtaaaat cagatttagt aagcagttta acatcagaaa
     5221 aacaaaacct acttatacaa aatctaaaag aaaaatataa tgttaaaatt acagataaat
     5281 atcaaatgaa agctaaagaa tagataaagt caatttatta aaaaaaagaa aaattaactg
     5341 tatggataaa agctattttt actctcaata tagagagtat aaaatagctt ttattatttt
//
LOCUS       DAMJXI010000136         5393 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.143, whole genome shotgun sequence.
ACCESSION   DAMJXI010000136 DAMJXI010000000
VERSION     DAMJXI010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5393
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.143"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            253..1716
                     /locus_tag="PC465_003658"
     CDS             253..1716
                     /locus_tag="PC465_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HDF2650925.1"
                     /translation="MTDLVNTINGIVWSPVLVAMCLCIGLYFSLKLKLFQIRDVKEMF
                     TLLLEGDSSHVGISSFQGFATSMAGRIGTGNIAGVAVAIAMGGPGALVWMCIMATLGS
                     ATAFVESTLAQIYKDEHDGQYRGGPPYYFEKGLGWKKCSVLFSIVAIISYTFFMPGTQ
                     SNTLYLAMNQAFGFSKMTIAVASSIALAIIIFGGIKRIGLFAEKVVPIMGGAYLIMTL
                     VIIITNISLVPEAIVTMFKSAFGFGSVFGGMLGSAISWGVKRGIYSNEAGEGSGTYGA
                     AAAEVSHPAKQGLVQAFSVYVDTLLICMATGIMIVITGMYNVTGVCTALPGVEPGPQY
                     VQSAINTLHPQLGDIFIAIVLLLFTFTTLLAFSYMMETNVSYLVTRIKAEKHEKYIIN
                     VCRFMLIACAAMCCFIEPLTSWALGDICIGVLTYINLIAIFTLKKPAIKAYYDYIRQK
                     KMGIKRSDRTFNPIELDIRNAEFWENRYLKEDKHELN"
     gene            1772..2908
                     /locus_tag="PC465_003659"
     CDS             1772..2908
                     /locus_tag="PC465_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2650926.1"
                     /translation="MKERIIQVADSKKEKILGLCQSLYDEPEIALQEYKSAKKISEFL
                     REEGFDVEENLAGMATAFKATKKNGDGPKIAFIAEYDALPGNGHACGHHLIASMGVGA
                     GIALSSILDTYKGEVSIIGTPAEETGDGKPYLIEHGVFDGYDAAMMIHPNSKTCVTPE
                     IIAIGGLDFIFTGKASHAGAKPYNGINALDAVVLLYNNINALRQQLVDGTRIHGIILE
                     AGTAANVIPDMGKVRLEIRAKEQNYFDEVVEKVKNCARGAAIATGCELEFYHFEPTCQ
                     GLNENKVLVDIFTKIMEEFGIYEDEQVMLGSTDMGNLSQIMPCIHPLMKFSENGEELH
                     TKEFLEASINSYAKDRVIDGIKILALTGFNLFENPELLKKMKEE"
     gene            3144..4259
                     /locus_tag="PC465_003660"
     CDS             3144..4259
                     /locus_tag="PC465_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HDF2650927.1"
                     /translation="METLEVRNIELSGTNYEIGYRLGELVANMPEIIEGQINKSNLVS
                     KKEEKEMIELFDKYCPGLNEELQGFADAIQVNCNQILYYTMTYLKPGCSQVALAPELT
                     ENGHVLFARNFDFSHNMEDFVLCKTKVNGKYAHIGTTIMQFGRGEGMNECGLGVSQSS
                     CGIPVGNSDGLRKPAIVGLQFWAVIRYLLENCKDVDEALEYLKDMPIAYNINLLLADK
                     SGNIALVETLDGKKEVNIINSLESKREYFLHSTNHTHIDKLHKLDPQSMKNSIHRYKL
                     IKEYINKSKKIGEKELMNLLSSKYPNGLFCNYYNDFFGTLKSIVMDLNIGKFNILWGG
                     LENKWESYYLKNDIKSITQRININIEKAPSDFFDFIE"
     gene            4411..5280
                     /locus_tag="PC465_003661"
     CDS             4411..5280
                     /locus_tag="PC465_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2650928.1"
                     /translation="MDYLKYFEKAVMYIENNLHENITVNDVAKETGYSYYHLTRLFKS
                     MFGESVGSYIKKRRLVSSTKELLYSDKKVIDIAIGSGFESSEAFSRAFKSIYKVSPIE
                     YRKNRIDVFVGKKKKLELDFMRHLVGNITIKPVIKEIEKIKVIGIKDKVILENNSLPD
                     LWEKFRKVHHIVPNTLPSKRVFGICEAISEIHLVSESMEFNEIIGLEVNSYDVIPNSF
                     VSKTIKEGKYAIFTHTGNLDNLDKTYEYIWGTWFLSSKEELDIRDDFEVYDERFLGPS
                     NVNSQIDIYIPIK"
BASE COUNT         2085 a          547 c          999 g         1762 t
ORIGIN      
        1 tatatgtatt ccaatttata ttgtttgatt attattcaaa cacacgtcgt taaaaatttt
       61 ataaatttat gtttagatat gattaatact cttgatttta gaaataaata tttgtagatt
      121 gtagattaaa gataatataa ataaatagaa ggtagatttt ttagatatat taatataaag
      181 attatataaa atattgaaat atagctgttt aaattattgt ctataaatat aaaatgaatg
      241 gtggtgagtt aagtgaccga tttagttaac accattaatg gaattgtttg gtcacccgta
      301 ttagttgcaa tgtgtttgtg tataggatta tatttttcat tgaaattaaa actttttcaa
      361 ataagagatg taaaagaaat gtttactctc ttgcttgaag gagatagttc tcatgttggt
      421 atatcatcat ttcaaggttt tgctacatct atggctggaa gaatagggac tggaaatata
      481 gctggtgtag ctgtagcaat agcaatggga ggtccaggag cattagtatg gatgtgtata
      541 atggctacat taggttcagc aactgcattt gtagaatcta ctttagctca aatatataaa
      601 gatgagcatg atgggcagta tagaggagga cctccatatt attttgaaaa aggtcttggg
      661 tggaaaaagt gttcagtttt attttcaata gttgcaataa taagttatac attttttatg
      721 cctggtacac aatcaaacac tttatatcta gcaatgaatc aagcatttgg attttcaaaa
      781 atgacaatag cagtagcatc ttctattgca ttagcgataa taatttttgg aggaattaaa
      841 aggattggtt tatttgctga aaaagtagta cctataatgg gtggagcata ccttattatg
      901 acattagtaa taattataac aaatattagt ttagttccag aggctattgt aacaatgttt
      961 aaatctgcat ttggatttgg ttcagttttt ggaggaatgc taggttcagc aatatcttgg
     1021 ggagtaaaaa gaggtatata ctcaaatgaa gcaggagaag gttctgggac ttatggtgcg
     1081 gcagcagcag aagtaagtca tccagccaaa caaggattag ttcaagcatt ttctgtttat
     1141 gtagacacat tattaatatg tatggctaca ggtattatga ttgtaataac aggaatgtat
     1201 aatgttacag gtgtttgcac agcactacca ggtgtagaac cgggaccaca atatgtacag
     1261 agtgcaataa atacattaca tccacaatta ggtgatattt ttatagcaat agttttatta
     1321 ttatttacat ttacaacttt attagccttc tcatatatga tggagactaa tgtatcttac
     1381 ttagtaacta gaattaaagc agaaaaacat gaaaagtaca taattaatgt ctgtagattt
     1441 atgcttatag catgtgcagc aatgtgttgt tttatagaac cacttacaag ctgggcatta
     1501 ggtgatatat gtataggtgt attaacatat ataaatttaa ttgccatctt tacactaaaa
     1561 aaaccagcta taaaggcata ttatgattat ataagacaga agaagatggg aataaaaagg
     1621 agtgatagaa cttttaaccc tatagagtta gatataagaa atgctgagtt ttgggaaaat
     1681 agatacttaa aagaggataa gcatgagtta aattaaagtt ataataaaat ataaaaatta
     1741 ctaaataaat ttagtgggag gtaagattgg tatgaaagaa agaataatac aagtggctga
     1801 ttcaaagaaa gaaaaaattc tagggctatg tcaatcttta tatgatgaac cagaaattgc
     1861 tttgcaagaa tataaatctg ctaaaaaaat atcagaattt ctaagagaag agggttttga
     1921 tgttgaggaa aacttggcag gtatggctac agcttttaaa gcaaccaaga aaaatggaga
     1981 tggtcctaaa atagcattta tagcagaata tgatgctctt ccaggcaatg gacatgcatg
     2041 tggacatcat ttaattgcat ctatgggagt tggagctgga atagctcttt caagtatact
     2101 ggatacttac aagggagaag taagtataat tggaacacct gctgaagaaa ctggagatgg
     2161 aaagccttac ttgatagaac atggtgtatt tgatggctat gatgcagcaa tgatgataca
     2221 tccaaattca aaaacttgtg taacacctga aattatagca ataggaggtc tagatttcat
     2281 atttactgga aaagcatctc atgcaggagc taagccatat aacggaataa atgctttaga
     2341 tgcagtagta ctactatata ataatataaa tgcactaaga caacaattag tagatggaac
     2401 gagaatacat ggtattatat tagaagcagg aactgctgca aatgtaatac ctgatatggg
     2461 aaaagtaaga ttagagataa gggcaaaaga acaaaattac tttgatgaag tagtagaaaa
     2521 agtgaaaaat tgtgctagag gtgctgcaat agccactgga tgtgaacttg aattttatca
     2581 ctttgaacca acttgccaag gattaaatga aaataaagtt ttggtagata tatttacaaa
     2641 gattatggag gaatttggaa tatatgaaga tgaacaagta atgttaggtt caacagatat
     2701 gggaaattta agtcaaataa tgccatgtat acatcctttg atgaagtttt ctgaaaatgg
     2761 agaagaacta catacaaaag aatttttgga ggcttctata aattcatatg caaaagatag
     2821 agtaattgat ggtataaaaa tattagcttt aacaggattt aatttatttg aaaatccaga
     2881 attattgaaa aaaatgaagg aagagtagaa cttagactat ttttaattat actctttaaa
     2941 ataagaagag tgtctcaaaa tgaacttttt agtttatgag acactctttt ttgtatgaaa
     3001 ttaaatatat ttttattatt ttaaacatga aaaagaggct tatctgtttt tatatgacct
     3061 tttttaactt gtagcacaaa atatcatgaa tgattacaat tcgaatgata aaatcgatta
     3121 taagatatat aggaggggta catatggaaa ctttagaagt aagaaatatt gaattgagtg
     3181 gtacaaatta tgagatagga tacagactag gagaattggt tgctaatatg ccagagataa
     3241 tagaaggtca gattaataaa tctaatctgg taagcaaaaa agaagaaaaa gagatgatag
     3301 agttgtttga taaatattgt ccaggtctta atgaagaatt gcaaggtttt gctgatgcaa
     3361 ttcaagtgaa ttgtaatcaa attttatatt atactatgac ttatcttaaa ccaggttgta
     3421 gtcaagttgc attagcacca gaattaactg aaaatgggca tgtactattt gcacgtaatt
     3481 tcgatttctc acacaatatg gaggattttg ttttatgtaa aactaaggta aatggaaaat
     3541 atgcacatat aggtactacc attatgcaat ttggaagagg tgaaggtatg aatgaatgtg
     3601 gcttaggtgt aagtcagtca tcatgtggta ttcctgtagg caattcagat ggtttaagaa
     3661 aaccagcaat tgtaggttta cagttttggg ctgttattag atatttgtta gaaaattgca
     3721 aagatgtaga tgaagcatta gaatatttaa aagatatgcc aattgcatac aatattaatt
     3781 tattgcttgc agataagtct ggaaacattg cacttgtgga gactttagat gggaaaaaag
     3841 aagtaaatat aatcaacagt ttagaaagta aaagagaata ttttttacac tctactaatc
     3901 atacacatat tgataaactt cataaattag atccacaatc aatgaaaaat tctattcata
     3961 gatataaatt aattaaagaa tatataaata agtctaaaaa aattggagag aaagagttaa
     4021 tgaatttatt gtcttcaaaa tatccaaatg gcttattttg taattactat aatgattttt
     4081 ttggaacttt aaaaagtata gttatggatt taaatatagg aaagtttaat attttatggg
     4141 gtggactaga gaataaatgg gagagctact atttaaaaaa tgacattaaa tctataacac
     4201 agaggataaa cataaatatt gaaaaagcac catctgactt ttttgatttc attgaataaa
     4261 aaatgtattc aattattcta aataattagg atatataaat caactaaaag tttttattta
     4321 tcgtattgaa ttagttataa tattttagta tagtaaaaaa tagtgctatt ttacatattt
     4381 aaagagttta agtaaaagag aggtgccata ttggattact taaagtattt tgaaaaagct
     4441 gtaatgtata ttgagaataa tttacatgaa aatataactg taaatgatgt ggcaaaagaa
     4501 actggatatt cttattatca tttaacacgc ttatttaagt ctatgtttgg tgagagtgta
     4561 ggaagttata taaaaaaaag acgattagta agtagtacaa aagaactttt atatagtgat
     4621 aaaaaagtga tagatatagc tattggtagt ggatttgaat cttcagaagc atttagcaga
     4681 gcatttaaat ctatatacaa ggttagccct atagaatata gaaaaaatag aattgatgta
     4741 tttgttggta aaaagaaaaa attagagtta gattttatga gacatcttgt tggaaatata
     4801 acgattaaac cagttataaa agaaatagaa aaaataaagg taataggtat aaaggataaa
     4861 gtaattttag aaaataattc attacctgac ttgtgggaga aattcagaaa agtacatcat
     4921 attgtcccaa atactttgcc atcaaagaga gtttttggaa tctgtgaagc aatctctgaa
     4981 atacacctag ttagtgaaag tatggaattt aatgagataa taggacttga agttaatagt
     5041 tatgatgtga ttccaaattc atttgtttca aaaactatta aggaaggaaa gtatgctata
     5101 tttactcata ctggtaactt agataattta gacaaaactt atgaatatat atggggtact
     5161 tggtttttaa gttcaaaaga agaacttgat ataagagatg attttgaagt atatgatgaa
     5221 cgatttttag gtcctagtaa tgtgaactca caaattgata tttatatacc tataaaataa
     5281 tctataagaa aactaaaaaa taatttgatt aagaaataga tgttcgtaaa agagcatcta
     5341 ttttttattt ttataagatt tagataattt taataataaa agaaataaaa ata
//
LOCUS       DAMJXI010000137         5312 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.144, whole genome shotgun sequence.
ACCESSION   DAMJXI010000137 DAMJXI010000000
VERSION     DAMJXI010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5312
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.144"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            593..1900
                     /locus_tag="PC465_003662"
     CDS             593..1900
                     /locus_tag="PC465_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650929.1"
                     /translation="MKEIADAITSEYLSYGINEDISIYEGRFCIYLDKKYRCNGKIYY
                     KMTPPISISFKADIGCVEEIDNEDDNLALDYDNAILEVHGYKIISITINTLSEFSVEG
                     YINDDCIKSKNSYVEYVDFNIINLDKIPGKLIKYNDKVYAGRIEFDINDYVVTIDKRY
                     DYRKELKSELKSKSGAIITHIGRIRRKDGRIFRTNNTINLLDRISTALSFMCGRYVGF
                     CLAKGYRSGNEVYRIWNENQISPFRYVPTWSDTLSNYHNMEKYISLMCKKLEDFYYGS
                     AIKSVVDWYIESLGSATMENNIISVQIALETLSYVILVEQNKILTDEVFDCNLASKNI
                     RLLLDTCKIPYGKHELNIFDNIIKNKFDDGVDLVIYLRNSIVHPSRKTHRAVLEVEDI
                     WNIISIGTRYIELVLLFILGYRGEYSNRLVERCYGEVEVVPWN"
     misc_binding    1986..2248
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            2374..3177
                     /locus_tag="PC465_003663"
     CDS             2374..3177
                     /locus_tag="PC465_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2650930.1"
                     /translation="MKNILKKVGIFTIMLGLLGGVVGCSKPNNEKDKDASKESKKEVV
                     VGFDNTFVPMGFLDEKGDTVGFDVDLAKETFKRLGMEVKFQPIDWSMKETELNDSKTV
                     DVLWNGYSITDERKKIVSYTEPYLQNKQIIVTLSDSKINSKADLKDKEVGTQQGSTAL
                     DAVEKDKDFMNSLKGGAPVLYDTYDKALRDLEIGRTSAVVGDEVLIRYYMGQKGEDKY
                     KVLKDDFGLEDYVVATSKENPELCEKINETLKEMKKDGTFDKIYDKWFK"
     gene            3215..3826
                     /locus_tag="PC465_003664"
     CDS             3215..3826
                     /locus_tag="PC465_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF2650931.1"
                     /translation="MLQGLEIVIAMFCITLIVSIPLGIGVAFLRLSKNKLVSGITQCY
                     ILIMRGTPLLLQMIVIFYGLPLLGIVFDRFTAGVVAFFLNYAAYFAEIFRGGIQSIDR
                     GQYEASKVLGFDKFTMYKRVIFPQVFKRILAPISNEVITLVKDTSLVYILGLNDILRI
                     SQIAMNREASLLPLFEAGAIYLIFVAILTKGFELLEKKYSYYR"
     gene            3858..4529
                     /locus_tag="PC465_003665"
     CDS             3858..4529
                     /locus_tag="PC465_003665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDF2650932.1"
                     /translation="MLKIKNLNKSFKKNRVLKDISFELEEGQIGVLLGKSGAGKTTIL
                     RCINGLEEFDSGEIIIDNEVIKNKRDMAKIRGKIGMVFQNFNLFPHMTVLENIIESPV
                     NVFKVPRKEAEERARELLRLVDLEDKLNSYPFELSGGQQQRVAIARSCALMPKVLCFD
                     EPTSALDIDTIQRVVNIMNRLKDKGMTILIITHDVVFSNNVADKIISIKDGIVENVQI
                     KEKIV"
     gene            4828..5190
                     /locus_tag="PC465_003666"
     CDS             4828..5190
                     /locus_tag="PC465_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HDF2650933.1"
                     /translation="MIKLYGYTKCSTVKKAKNWLKENNLEFEDIDMVQNPPSKEELKS
                     IYKTSGYDIKKFFNTSGMKYRELGLKDIVKTESDDKLLEILVSDGMLIKRPLLLDGKN
                     VLLGFKEDVWKSTLLKED"
BASE COUNT         2162 a          463 c          930 g         1757 t
ORIGIN      
        1 agataataaa acaacaatgg tgctaattta tatgtataaa ttaattatga aaaatttata
       61 taagtaaaat atattaacat aaaggtaaaa ttttgtatac taaaagggaa tatttacagt
      121 ttaatggcag ttttaaaata ataaattaaa gctgtcattt ttatttaaaa atttttagaa
      181 aaagtacaat agtgttaatg tgtgaattag ataaggtgta tataatagtt tagatgatat
      241 gatataaaat atgttgtaaa ttaaatgttt tctttgacaa tatatacaca aggatgataa
      301 tatctatatg aataaaagat agtgtgtaat ttgataatat gtaattataa cattatgata
      361 taattacaat aaagtatgta ataatctgta gaaatttcaa gctagttatc taagtcggat
      421 aactaaatct aaacggaata cataatgtat taaataaatg atgatactaa aatgatacta
      481 tttttataga aatttattga ggtatataat taatgaaaat aatatattaa attatataaa
      541 ttaaattata taatatattg agttttacat aaaagcaaag gtgggaataa aaatgaaaga
      601 aattgctgat gctataacat cagagtattt aagctatggt atcaatgaag atattagtat
      661 ctatgaaggt agattttgca tatatttaga taaaaaatat agatgtaatg ggaaaattta
      721 ttataaaatg acacctccaa tatctataag ttttaaagca gacataggtt gtgttgaaga
      781 gatagacaat gaagatgaca atttagcttt agattatgat aatgctattc ttgaagttca
      841 tggatataaa attatttcta taacaataaa tactttaagt gaatttagtg tagaaggtta
      901 tatcaatgat gactgcataa aatctaagaa ctcctatgtt gaatatgtag attttaatat
      961 aataaactta gataaaatac ctggaaaact cattaaatac aatgataagg tatacgcagg
     1021 tagaattgaa tttgatataa atgattatgt tgtaactata gacaagcgat atgattatag
     1081 aaaagaatta aaatcagaat taaagtctaa atctggagca ataataactc atataggtag
     1141 gattagaaga aaagatggta gaatttttag aacaaataat acaataaatc ttttagatag
     1201 gatatcaaca gctttgagtt ttatgtgtgg aagatatgta gggttttgtt tggccaaagg
     1261 gtatagaagt ggtaatgaag tttatagaat atggaatgaa aatcaaatat ctccttttag
     1321 atatgtacca acatggtcag atacactttc aaattatcat aatatggaaa aatatataag
     1381 ccttatgtgt aaaaagctag aagattttta ttatggttct gctataaaga gtgttgttga
     1441 ttggtacata gaatctcttg gaagtgctac catggaaaac aatataatat ctgtacaaat
     1501 tgcacttgaa actttgtcat atgtaattct agtggaacaa aataagatac ttacagatga
     1561 agtatttgac tgtaatttgg catctaaaaa tataagactc ttacttgata catgtaagat
     1621 accatatggt aaacatgaat taaatatatt tgataatata ataaaaaata aatttgatga
     1681 tggagtggat ttagttattt atttaagaaa tagcatagtt catccaagta gaaagactca
     1741 tagagctgtg ttagaggttg aagatatttg gaatataatt tcaataggaa cgagatatat
     1801 tgaacttgtt ttactcttta ttttaggtta tagaggagaa tattcaaaca gattagtaga
     1861 aagatgttat ggtgaagtgg aagttgtacc ttggaactag atttttatat ttattttaaa
     1921 atatatattg acatatattg ccttatgcta taaaatcaat atcataataa taattcagaa
     1981 taacattaaa tgctaagaaa agaaatagta aaagtagtta atcttaaaca gagagtttcc
     2041 gattggtgag aggagcaata gattttactt tgaacacatc tttgagcagg actctgaaag
     2101 agtagaaata ctttattagg agatttccgg aatccttgca cccgttatag tgctagagta
     2161 taataatttt attgtactta aagaggttag tgtcgtgagg cattaatgaa cagaggtgga
     2221 accacgagag ttaactcccg tcctctagca gaagctagag gcgggagttt tttaatataa
     2281 ttttttaagc gcgcagagaa ttatattgca atagatacac tttttaaaaa ataatcaaaa
     2341 tattttaaaa attaaaagac gagggagaat attatgaaaa atatattaaa aaaagtagga
     2401 atatttacaa ttatgttagg tttattaggt ggagttgtag gttgttcaaa accaaataat
     2461 gaaaaagata aggatgcttc aaaggaatct aaaaaagaag tagttgtagg gtttgataat
     2521 acgtttgtac caatgggatt tttagatgaa aagggagata cagtaggatt tgacgtagac
     2581 ttagctaaag aaacatttaa aagacttgga atggaagtta agtttcagcc tatagattgg
     2641 tcaatgaagg aaactgaatt aaatgattca aaaactgtag atgtattatg gaatggatat
     2701 tctataacag acgaaagaaa gaaaatagta tcatatacag aaccatattt acaaaataaa
     2761 cagataatag ttactctaag tgactcaaaa ataaattcaa aagctgattt aaaagataaa
     2821 gaagttggaa cacaacaagg ttcaacagca cttgatgcag tggaaaagga taaagatttt
     2881 atgaatagtt taaaaggtgg agcaccagtt ctttatgata cttatgataa agcacttaga
     2941 gatttagaga taggtagaac tagtgcagtt gttggtgatg aagttttaat tagatactat
     3001 atgggacaaa agggtgaaga caaatacaag gtattaaaag acgattttgg attagaagat
     3061 tatgttgtag caacttctaa agaaaatcca gaactttgtg agaaaataaa tgaaacatta
     3121 aaagaaatga aaaaagatgg aacttttgac aaaatttatg ataagtggtt taaatagaag
     3181 ataagttagc agttaagaag ggggcactaa aggcatgtta caaggtttag agatagttat
     3241 agcaatgttt tgtataacat tgatagtatc aattccattg gggattggag ttgcattttt
     3301 aagattatca aagaataaat tagtaagtgg tattacacaa tgttatatat tgataatgag
     3361 aggtacacct ttacttttgc aaatgatagt catattttac ggattacctc ttttaggaat
     3421 tgtatttgac agatttacag ctggagtagt agctttcttc ttaaattatg cagcatattt
     3481 tgcagaaata tttagaggtg gaatacagtc aatcgataga ggacaatatg aagcttcaaa
     3541 agtactagga tttgataagt ttactatgta taagagagta atctttccac aagtttttaa
     3601 aagaatacta gcacctattt caaatgaagt aatcacatta gtaaaagata catctttagt
     3661 atatatatta ggattaaatg atattttaag aatatctcaa atagcaatga acagggaagc
     3721 aagtctgtta ccattatttg aggcaggagc gatatatctt atatttgtag ctatacttac
     3781 taagggattt gaattacttg aaaaaaaata ttcttattat agataaagtt acaatattat
     3841 aggaggaggt tttttatatg ttgaaaatca aaaacttaaa taaatcattt aaaaaaaata
     3901 gagtacttaa agatatttct tttgagttag aagaaggtca gattggagtt ttacttggta
     3961 agtctggtgc aggaaagacc acaatattaa ggtgtataaa tggtcttgaa gaatttgata
     4021 gtggagagat tataatagat aatgaggtaa taaaaaataa gagagatatg gcaaaaatac
     4081 gaggaaaaat aggtatggtt tttcaaaatt tcaacttatt tcctcatatg acagtccttg
     4141 aaaatataat tgaatcccca gttaatgttt ttaaagttcc tagaaaagag gctgaagaga
     4201 gggctagaga acttttaaga ttagttgatt tagaagataa attaaattct tatccatttg
     4261 aattgtcagg aggacagcaa cagagagttg ctatagctag gtcatgtgca ttgatgccaa
     4321 aagtcctttg ttttgatgaa cctacttctg cacttgatat tgatactatt caaagagtag
     4381 tcaatataat gaacagactt aaagacaaag gtatgacaat attaataatt acacatgatg
     4441 ttgtcttctc aaataatgtt gcagataaaa ttataagtat aaaagatggt atagtagaaa
     4501 atgttcaaat aaaagaaaaa attgtttaga gttttataaa tataaactag ggtagaattt
     4561 tataatataa ataaagggca agtaaaatca aatatactat gcccttttgt tatctcaaaa
     4621 tttaatctta tattttatgt ttaagttaca ttataattta taataaaaat aaaaggacta
     4681 tttaaatata taatgtgaat aaatgtttaa taatttgaaa tatgataatt ttttatgttg
     4741 aaagcttata atgattatga tataaattgg ttatagtata caatttatgg gtataacagt
     4801 aaaaaattag aaaggaattt ttataaaatg attaaattat atggatatac aaaatgctct
     4861 actgttaaaa aagctaaaaa ttggcttaag gaaaataatt tagaatttga agatatagat
     4921 atggttcaaa atcctcctag taaagaggag ttaaaatcaa tttataagac tagtggatat
     4981 gatataaaga aattttttaa tacaagtggt atgaaatata gagaattggg tcttaaagat
     5041 attgtaaaaa ctgaatctga tgataaactt ttagaaatat tggtaagtga tggtatgctt
     5101 attaaaagac cattactttt ggatggtaaa aatgtattat tgggctttaa agaagatgta
     5161 tggaaaagta ctttgctaaa agaagattag aaagagatag gtgtgttgat taaaattatt
     5221 aattaataca cctataaatt tatgtattaa atctaatttt tataaatatt aattagcaaa
     5281 ttcaaatcaa aaaaattcat atcagcaaac at
//
LOCUS       DAMJXI010000138         5273 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.145, whole genome shotgun sequence.
ACCESSION   DAMJXI010000138 DAMJXI010000000
VERSION     DAMJXI010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5273
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.145"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(286..486)
                     /locus_tag="PC465_003667"
     CDS             complement(286..486)
                     /locus_tag="PC465_003667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF2650934.1"
                     /translation="MNNGIVKWFNNEKGFGFISMESGDDVFAHFSAIQTSGFKSLEEG
                     QKVSFDIVKGARGPQAENITIL"
     gene            complement(711..887)
                     /locus_tag="PC465_003668"
     CDS             complement(711..887)
                     /locus_tag="PC465_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650935.1"
                     /translation="MFRDKMDKCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGEKVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(941..1030)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(1210..1410)
                     /locus_tag="PC465_003669"
     CDS             complement(1210..1410)
                     /locus_tag="PC465_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2650936.1"
                     /translation="MPKFTCNLKKYRQLKELTQEQLAEKVGVRRETIMRLEAGKYNPS
                     LKLAIDISKIVDTPIDELFIFD"
     gene            complement(1412..1762)
                     /locus_tag="PC465_003670"
     CDS             complement(1412..1762)
                     /locus_tag="PC465_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3796 domain-containing protein"
                     /protein_id="HDF2650937.1"
                     /translation="MIQKKFFMGFCGFLGFLSLRYFSSGNVADLTYIGFFAFFSNFII
                     AKINGDKADERYVQDEKAAMAFTGQLAIIELFILWCITIVSRNIELMCVLLSITYAIT
                     LNVYAIKLYILEEK"
     gene            1924..2113
                     /locus_tag="PC465_003671"
                     /pseudo
     CDS             1924..2113
                     /locus_tag="PC465_003671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890498.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2590..2760)
                     /locus_tag="PC465_003672"
     CDS             complement(2590..2760)
                     /locus_tag="PC465_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650938.1"
                     /translation="MHVYQPKTSEYLLNTYAKSYLSSIVFLFDYITKNESRYAFFIID
                     FPFLSLDIFYKF"
     gene            complement(3149..3637)
                     /locus_tag="PC465_003673"
     CDS             complement(3149..3637)
                     /locus_tag="PC465_003673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2650939.1"
                     /translation="MKNKKGFTLVELLVVIAIIGILAIVALPALFKNIEKAKIAKLEA
                     DISAIKSASLSYYADESKYTEGNIIWWTKKDGKITVNSGIGDEDPLAHKIENLGMPYN
                     GSYTLVSSNGSEEYLELNIIIDGEISKSGLDKLEEDYGSSITIPNDKNMIITFLSNKS
                     DN"
     gene            4441..4815
                     /locus_tag="PC465_003674"
     CDS             4441..4815
                     /locus_tag="PC465_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2650940.1"
                     /translation="MKEEILIEKLLRAELIVMEYLWKKDTLMPKKEIVKEIKQIYGWH
                     KSTIKILLKRLVAKRYLARYIINSQSHYKIIDSKEYYTFKKKVLKSSKSIKIMRSLTT
                     THKNVSKEKLDLLDEYYRNLKE"
     gene            4920..5273
                     /locus_tag="PC465_003675"
                     /pseudo
     CDS             4920..5273
                     /locus_tag="PC465_003675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
BASE COUNT         2123 a          642 c          608 g         1900 t
ORIGIN      
        1 atcagaattg aatacaaaag aaagagtatg tatttatgag atagttgaaa attttgatgt
       61 gccacaacta aaattattat attactatat attctaatta aaagagtact tgtaggttta
      121 agtacatact ttataaatat atttttgtca gatttatttt ataaaaagta tttagactaa
      181 gtattatttt taagtatttt tttgttgaag ttattttttc cttttttaca aaatgcgtaa
      241 ataaaaaaaa gactcttaaa agagtctttc cgaaaaatct atatattata atatagttat
      301 attttctgct tgaggacctc tagcgccttt aactatatca aagcttactt tttgaccttc
      361 ttctaatgat ttaaatcctg aagtttgtat agctgagaaa tgagcaaata cgtcatctcc
      421 actttccatt gatataaatc caaatccttt ttcattatta aaccatttta ctattccatt
      481 attcattaaa aatactccta ttaacctata tcaagatata cttgatttac ttgtgtatta
      541 ccacaaatac tattgtatca tagattaaca taaatgtcta tttaattata atttttagtt
      601 aacattttta tttattctta atatgaaaat aaatttaaac attttatatt accaatatat
      661 taatgtaaat gtagataaaa ctaaaaaggg ttttctagaa aaaaatctgt ctaattatac
      721 ttacttacca ataccatcac ttgatgcaag caagattcca caactttttc tccgtactct
      781 aatataaaat catctaactg tgtatctata aaatcacaat aatcatatga actaccaata
      841 taagcagtta acatatgtgt acatttatcc attttatctc taaacataat gtatttatcc
      901 ccctaaaaaa ctttcatgaa aaacaaaaag aaaatatctt tttggcaact ggctgacata
      961 acttatttta taagcgttag tccctatagc tttgcgtcac taaatttctc tagttttgcc
     1021 gatttagttt tattctacag attaataata caatagaatt agttattatt caacatatct
     1081 agctgaaaaa ttaataaatt tatatatgaa cgttaaatta tctgaaaaaa taaaaagccc
     1141 ctctgtcagg agtgacttaa aaattgaatt taagtttgta tttaaaacac atttttaata
     1201 atgcaaaaac taatcaaaaa taaacaattc atcaataggt gtatctacta tttttgatat
     1261 atctattgct aatttcaaag aaggattata ctttcctgct tctaaacgca taatggtttc
     1321 tcttctaact cctacttttt ctgctaattg ttcttgagtt aattctttta attgtctata
     1381 tttttttagg ttacaagtga atttaggcat attatttttc ctctaaaata taaagtttta
     1441 tagcataaac atttaaagtg attgcatatg taattgatag taaaacacac attaattcta
     1501 tattcctaga cactatagta atacaccata aaatgaataa ttctataata gcaagctgtc
     1561 ctgtaaatgc catagctgct ttttcatctt gtacatacct ttcatctgct ttatcaccat
     1621 ttatttttgc tataataaag tttgagaaaa aagcaaaaaa tccaatatat gtaaggtcag
     1681 caacattgcc agatgaaaaa tatctaagac ttaaaaatcc aaggaaacca caaaaaccca
     1741 taaaaaattt tttctgaatc attttttatc ctccttagta attttaaaag agatatattt
     1801 atatctttat gatacaaata tatctctttt atattctttt gtcaatagaa aatcagtatt
     1861 atacaatatt tgtactgcac cataattgtt agagcaaaaa tctactgctt gagatgttta
     1921 tgtatgacta aatatgattt taatttcaaa ttaaaagtag ctaaatttta tttgaataga
     1981 gaaggaagag atattttaat agtaaaacaa tatggagttt ataaccattc tcaagttgaa
     2041 agatgggtta atatattagg agagtgtgca ctaaaaataa aaaaaatttt ctatactata
     2101 tggttcaagt tagatgttat aaactatatg atgataacta aatatagtgt acaataaatc
     2161 gctaagtatt ttggaataaa caatagcaca gttatagcaa catgaaaata aaaattttta
     2221 catagtggtg ttgatgcctt ttctaaaatg aaaggaagac cataatgaat aaaaacaaaa
     2281 acactaaaga aaaaataaat taacaagaga acaagaatta gaatatgaaa ataaattttt
     2341 aaaagatgag cttgagtttt taaaaaagat gtgtgtctca gggaagccac attaaaaaac
     2401 agtggtatca ttattaatca aaagaaagtt agatgtatta tcaaaaaatt agaacttaaa
     2461 tgcatagcat tttttcataa atcacataaa tataactcct ataaaggtat aattggaaaa
     2521 gtaaaaaata ataaaacaaa tagaagattt aaaacatcaa tagcatatca gaaaataaca
     2581 aatgatatgc tagaatttat aaaatatatc taatgataaa aatggaaaat caattataaa
     2641 aaaggcatat ctcgattcat tttttgttat atagtcaaat aagaatacta tagatgaaag
     2701 atacgatttt gcatatgtat taagtaagta ttctgatgtt tttggttgat acacatgcaa
     2761 taaagaagtt gtgtttgcag ataaattagc aaaactatag tataagttgc aacaataaag
     2821 aaaatgaaaa ttatcatact aaagcataag gcatgttaca attttattag ataggacatt
     2881 aacatacact aaagtacttt ttattataaa gagtacttat ttttttgaaa ttcattaatg
     2941 tataaactat caagaatatt actcaacata atttaaaaac aacttgaata ggtattttta
     3001 aattatgtga tataataaaa aatagaagtg tatgccaata cacttctgta gttataacta
     3061 agcattctat tcttgaggag tgcttttttc atttttataa ccaactcttt ttactttaac
     3121 aataattatc agacctatat atttattttt aattgtctga tttattagat aaaaaagtta
     3181 ttatcatatt tttatcattt ggtattgtta ttgaactacc ataatcttct tctaatttat
     3241 ctagaccact tttacttatt tctccatcta taattatgtt taattctaag tattcttcac
     3301 taccattaga tgacactaaa gtgtacgaac cattataagg catgcctaaa ttttctattt
     3361 tatgtgccaa agggtcttca tcaccaatac cagagtttac tgttattttt ccatcttttt
     3421 tagtccacca tattatgttt ccttcagtat attttgattc atctgcatag tagctaagag
     3481 acgcactttt tattgcactt atatcagctt caagtttagc tatctttgct ttttctatat
     3541 ttttaaataa tgctggaagt gctactattg ccaatattcc tattatagca attactacta
     3601 ataattccac tagagtaaat ccttttttat ttttcattta tttcccctcc atataaaatt
     3661 aataatatat aaatttttat tttgttgatt tctactttct atattttacc atatatagac
     3721 aaaaaaatca ctttctatga caaatatact attattttac aatttatgga aatgatttaa
     3781 aatgacattt cttgttagaa aagatataag aaatggatta aaataaagaa aactacagtc
     3841 atatcaatgt caataatatt atttaaaagc agatgaaaat aaaaagagga ctcagaaaat
     3901 aatgtctatt taattatact tacttaccaa taccataact tgatataaac aagattatac
     3961 tacatttttt tatgctctag tataaaatca tctaactgtg tatctataaa atcaaaataa
     4021 ttatatgaac tatcagtata ataagtcaaa atatgtatac atgaatacat attttaaaag
     4081 atatatatta ttacatacct aaaaaacttt cataaaaaca aaaataaaat atgcttttag
     4141 taacttgtta acataactta taatttattt tataagcatt agcctatata gctttgtgct
     4201 actaaatctc tttgattcta acgatttagt gctattctac aactaaaata atacaataga
     4261 gctatttatt gtttggtagc attgtttgta aattaaacaa atttatacat atgaatatta
     4321 ttttacattc aaaaaaacag actaaatatg tagaatattt ggtaaaactt acctctagtt
     4381 tttgtcttaa aaagctccta ttattaactt aagttagaag aattaaggaa gtgacataaa
     4441 ttgaaagaag aaatattaat agaaaaatta ttaagagcag aattaatagt aatggagtat
     4501 ttatggaaaa aagacactct aatgcctaaa aaagaaattg taaaagaaat aaaacagatt
     4561 tatggatggc ataaaagtac aataaaaata ctactaaaaa ggctagttgc taaaaggtat
     4621 ttggctagat atattataaa ttctcaatct cattataaaa taatagatag taaagaatat
     4681 tatactttta agaaaaaggt actaaaatct agtaaaagca taaaaataat gcgttcactt
     4741 accactacac ataaaaatgt aagtaaagag aagttagacc tattagatga gtattataga
     4801 aacttaaaag aatgatatag taaaaatcga atgtaattat ttaccttaat tcttttgttt
     4861 gtaaaacttt attgatacag aatttaacat atacataaat tggtaaagga atgtatacta
     4921 tgaaaattag taaattacca gaagcggaat taaaagttat gagatatatt tgggaatcag
     4981 aaaaggtatt aatatcaaga gaaatcacca agtctatgga acaaaaatat gaatggaaag
     5041 atacaactat atttacagta ttaaaaagat tactaaagaa gagagttttt agaagcggag
     5101 aaaatagata agtgtacaca ctataatgta ttagtaaaaa aaataatatc agagatttta
     5161 aacaaaagaa tttttaaaga atacacataa aaattcaata ttaagtttaa tgtcagcact
     5221 atgtagtaag gatgatgaag tagatggtga tattttaaat ttattagaag aat
//
LOCUS       DAMJXI010000139         5190 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.147, whole genome shotgun sequence.
ACCESSION   DAMJXI010000139 DAMJXI010000000
VERSION     DAMJXI010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5190
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.147"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            60..1064
                     /locus_tag="PC465_003676"
     CDS             60..1064
                     /locus_tag="PC465_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2650941.1"
                     /translation="MRFKRILILMLTVAMIAGMLVGCANNPSNNPSSSKDNKSDISDK
                     SNSKKSVSMILDIEGTNNEAMNNSALLALNNAQKKLNIDTNKVESDDSSTFSNSIDIL
                     CNDNYDLIIAVGARFAKPLEMVAKKYPKQQFAIIDYEYDKQPSNITSISYEDNKSGYL
                     AGLIAGKMTESDKVGFIGGIKSSSRDKFESGFREGVKFSNSSIKDISVEYADVFKDSK
                     SVESIAKKMMDNGVDIIFSTTEDDSKAVIDAVRAKNKKVIATNKDQHELAPENVISSI
                     VKDFENPTYNLIQSFVKGNYKGGKVIENTVKSGSTGLAQNSSQNIPPDVLEYVNKNNK
                     "
     gene            1190..2302
                     /locus_tag="PC465_003677"
     CDS             1190..2302
                     /locus_tag="PC465_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2650942.1"
                     /translation="MKIKRILMACFVVVFTIFILAICNFDFGFDKVNKNNSNIDSAES
                     KQNESKSLPTSAEKDKSNSKSKNKEDDTEDDSYVRKTIGVLLDTENLNNESYNNNVLS
                     ALKRADEDFDVRIKLEKPKTSKSFKESIEKLHKYEPDLIIAVGARFAEPIKEAATKYP
                     KQQFAIVDYTYKVQPANVISVSFQDNVTGYLAGLIAGKMTDTGKVGFIGGVEGSSRDK
                     YESGFRKGLKTSNKDAELLVKYSNIFENPESARTIAKEMRDSDRDVVFSATEDDSKRA
                     IQVARENGGKVIAINKDQYDMAPDNVISSIIKDVEQPVYELIKNVAKDGFKGSKVMEF
                     KIKDGELGLTSKSSRNIPPDVLEYIKKEYNKVKDTY"
     gene            2791..3552
                     /locus_tag="PC465_003678"
     CDS             2791..3552
                     /locus_tag="PC465_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650943.1"
                     /translation="MEFTREPFILDDDLCLALVDKRISYLMENELKLRNIEIIKTIEC
                     KELYESIKYHPDICICNLGKGDIIVAPNVYNQYKELLSRYKFNIIKGEANLLNRYPYD
                     IPYNIAIVGDYAIHNFKYTDKAILDYIENNKLKKINIEQGYSKCSICIVDRTSIITSD
                     KGIWKSMKNTEIECLLIEKGHINLFEMNYGFIGGCTGLISKDKLAFCGDVKKHPDYER
                     IKSFVESKNKEIVTLSCENLLDIGSIVPLMTRKER"
     gene            3555..4373
                     /locus_tag="PC465_003679"
     CDS             3555..4373
                     /locus_tag="PC465_003679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sporulation protein YtxC"
                     /protein_id="HDF2650944.1"
                     /translation="MVEKDNISSMKFLRNNNVNDRLIYTNDIVEVVIDSAKQEVLNKK
                     ILNGTKAEQRALNIDEISTEITSMIISIMKEKLLKEYILKCYGRTYPEDKNNIYIYSL
                     NIFAKKEIFMRETVFTRVRNYIEENDFINVEGFIRFRMREFMKYISAIGDIAVEEYLI
                     KKDQDEFIRVLKYFIDTQEEKIDLLKVHIMEDNTFVLYDKNGNKIDSIDDEEIINMVI
                     RENLNYEDFLISTLLTLCPKKIEILDLLNNNCSKEIIDTVEAIFENKVSIIMEN"
     gene            4553..5155
                     /locus_tag="PC465_003680"
     CDS             4553..5155
                     /locus_tag="PC465_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 family protein"
                     /protein_id="HDF2650945.1"
                     /translation="MDNLIRILILAVIGGFIGYVTNVVAIRLIFRPIKPIKIPILNIE
                     IVGLIPKRRAEIAANVGEIIQEEFLSMDEILANIITDEDKEEVVRYIKARVKIIIHEK
                     VSFIPSGIKNMIQDYLGEIIESEVKQSIDELSKNIINKANERIDIQKMVEDKINELDL
                     YELEEIIIRIAKKELKHIEFLGLVLGFLIGIAQGLITMFI"
BASE COUNT         2178 a          477 c          930 g         1605 t
ORIGIN      
        1 taggatgtaa aaataaatag gatataaaaa tatcgtaaat gtatgaggag tgaaatttaa
       61 tgcgtttcaa aagaatattg atattgatgt taactgtagc aatgatagct ggaatgttgg
      121 ttgggtgtgc taataaccca agcaataatc ctagctctag caaagataat aaaagtgata
      181 taagcgataa aagtaattca aaaaaatctg tatcaatgat actagatatt gaaggaacaa
      241 ataatgaagc tatgaataat tcagctttat tagcattaaa caatgctcaa aagaaactta
      301 atatagatac aaacaaagtg gaatcagatg attcctcaac tttttctaat agtatagata
      361 ttttatgtaa tgacaattac gatttaatta tagctgtagg agctagattt gcaaaaccat
      421 tggagatggt agccaagaaa tatccaaagc aacaatttgc aattatagac tatgagtatg
      481 acaagcaacc ttctaatata acttcaattt cttatgaaga taataaatct ggatatctag
      541 ctggattaat tgctggaaaa atgactgaaa gcgataaggt tggttttata ggaggaataa
      601 agagctctag tagggataaa tttgaatcag gttttagaga gggtgttaaa ttttctaata
      661 gtagtataaa ggatatttca gttgagtatg cagatgtttt taaagatagc aaatcagtag
      721 aatctatagc taaaaaaatg atggataatg gagtggatat tattttttct actactgaag
      781 atgattcaaa agctgtaata gatgcagtaa gggcaaaaaa taaaaaagtt atagcaacga
      841 ataaagacca acatgagtta gctccagaaa atgttataag ttctattgta aaagattttg
      901 agaatcctac ttataatctg atacaaagtt ttgtaaaagg aaattataaa ggcggaaaag
      961 ttatagaaaa cacagttaag tctggaagta ctgggcttgc ccaaaatagt tctcaaaata
     1021 ttcctccaga tgtgttagaa tatgttaata agaacaataa ataatctact ataatatcca
     1081 agaatactta tgactttagt tatgaggtga attggatgtt ataatagaca tatatagaaa
     1141 gacatatgca gaggtaggtc agacctatct aaatcaggga gtgaattttg tgaaaataaa
     1201 aaggatattg atggcttgct ttgtagtagt ttttacaatt tttatattag ctatatgtaa
     1261 ttttgatttt ggatttgata aagtaaataa gaataattct aatatagata gtgctgaatc
     1321 gaaacagaat gagtctaaaa gtttgccaac ttcagcagaa aaggataaat caaatagcaa
     1381 aagtaagaat aaagaagatg acacagaaga tgattcatat gtaagaaaaa ctattggagt
     1441 attgttagat accgaaaact taaataacga atcatataat aacaatgtac tatcagcctt
     1501 aaaaagggct gacgaagatt ttgatgttag gataaaactt gaaaaaccaa agacttctaa
     1561 aagttttaaa gagagtatag aaaaactgca taagtatgaa ccagatttga taatagcagt
     1621 tggagccaga tttgcagagc caattaaaga agctgctact aaatatccca aacagcaatt
     1681 tgcaatagtt gactatactt ataaagttca gccagctaat gtaatttctg tatcatttca
     1741 agataatgtt actggatatt tagcaggact tattgcaggt aaaatgactg atactgggaa
     1801 agtcggtttt ataggaggag ttgagggttc tagtagagat aagtatgaat ctggatttag
     1861 aaaggggctt aaaacttcaa ataaagatgc tgagttacta gttaagtatt caaatatatt
     1921 tgaaaaccct gaatcagcta gaactattgc aaaggaaatg agagattctg atagagatgt
     1981 tgtattttca gctacagaag atgatagtaa aagagctatt caggtagcaa gagaaaatgg
     2041 tggtaaagtt atagctatta ataaagacca atacgatatg gctccagata atgtaataag
     2101 ttcaattata aaagatgtag aacaacctgt atatgaactg ataaagaacg ttgcaaaaga
     2161 tggttttaag ggaagtaaag taatggaatt taaaataaaa gatggagaac ttggcttgac
     2221 ttcaaagagc agtagaaata taccaccaga tgttttggaa tacataaaaa aagagtataa
     2281 caaagtgaaa gatacatatt aattattgag tagaagatta taaaaatata ctgattaagt
     2341 ttagattggt gataaaagga tatatttatt aaatttgtgc taactgtaca aaatatattg
     2401 attaagttta gattagtgat aaaaagatat atttattaaa tttgtgttaa cagtatggaa
     2461 tatactgatt aagtttagat tggtgataaa aggatatatt tattaaattt agtctaactg
     2521 tacaaaatat attgattgag tttagattag caataaaaag atatatttat taaatttgtg
     2581 ctaactgtac aaaatatatt gattaagttt agattagtga taaaaggata tatttattaa
     2641 atttgtgcta actgtacaaa actatactaa ttaagcttag attaactata taaaattata
     2701 acaataagtg tgtgggcaga aaaattctgc tacacacttt atttatattc acataaaaaa
     2761 tttatcaaaa aaaagaaaaa ggagtaaaaa atggaattta caagagaacc atttatacta
     2821 gatgacgatt tgtgtctagc tttggtggac aaaagaatta gttatctaat ggaaaatgaa
     2881 ttaaaattaa gaaatataga gataataaaa acaatagaat gtaaagaatt atatgaaagc
     2941 ataaaatatc acccggatat atgtatttgt aatttaggaa aaggagatat aattgttgcg
     3001 ccgaatgtat ataatcaata caaagagtta ttaagtagat ataaatttaa tataattaag
     3061 ggagaagcta atttattaaa tagataccct tatgatatac cttacaatat tgcgatagtt
     3121 ggtgactatg ctatacacaa ttttaagtat actgacaaag caatattaga ttatattgaa
     3181 aataataaac ttaaaaagat aaatatagag cagggctatt ctaaatgctc aatctgtata
     3241 gtagatagaa cgtctataat aacatcagat aaaggtattt ggaaaagtat gaagaataca
     3301 gaaatagagt gtttattgat agaaaaaggt cacataaatt tatttgagat gaattatgga
     3361 tttataggtg gatgtacagg gttgatttct aaggataaac tagctttttg tggagatgtt
     3421 aaaaaacatc ctgactatga acgtataaaa agttttgtag aaagtaaaaa caaggagata
     3481 gttacactta gctgtgaaaa tttactagat ataggttcta tagttcctct catgacaaga
     3541 aaggagcgat aactttggtt gagaaggata atatttcttc catgaaattt ttgaggaata
     3601 ataatgtaaa cgatagatta atatatacga atgacattgt agaagtagtg atagattctg
     3661 caaagcaaga agtgttaaat aaaaaaatac ttaatggtac taaagctgaa caaagagctt
     3721 taaatattga tgagatatca acggaaataa ctagtatgat aataagtata atgaaagaga
     3781 aacttttgaa agaatacatt ctaaaatgct atgggcgtac atatcctgaa gataaaaata
     3841 atatatacat atattcactg aacatatttg ctaaaaaaga gatttttatg agagaaacag
     3901 tatttactag ggtgagaaat tatatagaag aaaatgattt tataaatgta gaaggtttta
     3961 ttagatttag aatgagagaa tttatgaaat atatttctgc tataggtgat attgcagttg
     4021 aggagtattt aataaagaaa gaccaagatg aatttataag agttttaaaa tactttatag
     4081 atactcaaga agaaaagatt gatttgctta aagttcatat aatggaagat aatacatttg
     4141 ttttatacga taaaaatgga aataagatag acagtataga tgatgaagaa attataaata
     4201 tggtaataag agaaaattta aattatgagg actttttaat aagtacctta ttaactctat
     4261 gtcccaaaaa aatagaaata ttggatttgt taaataataa ttgctcaaag gaaattatag
     4321 atactgtaga agcaattttt gaaaataaag ttagtataat tatggaaaac tagaatctaa
     4381 gcatataaaa gctatccata taaaattaaa aaaattcttt ttaaatcgac acaaaagact
     4441 tataattgta tataaagcta tagtataact agaattatta agtataaaga atatctactt
     4501 gattaataca atatagctgg caaatataca attgataagg agtaatttta taatggataa
     4561 tttaattagg atactgatat tagctgttat tggtggattt ataggttatg ttacgaatgt
     4621 agttgctata agactgatat ttagaccaat aaagcctatt aaaataccta ttttaaatat
     4681 agaaatagta ggtcttatac caaagagaag agcagaaata gcagcaaatg taggagaaat
     4741 aattcaagaa gaatttcttt ctatggacga aatacttgca aatatcatta ctgacgaaga
     4801 taaggaagaa gttgtaagat acataaaagc aagggtaaaa attataatac atgagaaagt
     4861 ttcatttatc ccgagtggta taaaaaacat gatacaagat tatctaggag agataattga
     4921 gtctgaagtt aagcaaagta tagatgaatt gagtaaaaat ataataaata aagcaaatga
     4981 acgtatagat atacaaaaaa tggtcgaaga taagattaat gaactagatt tatatgaatt
     5041 ggaagagata ataataagaa tagctaagaa agaattaaaa catatagagt ttttggggct
     5101 tgtcttaggg tttttaatag gtatagctca agggttaatt actatgttta tttaaatata
     5161 tgagaagtag catttattta agtactaatt
//
LOCUS       DAMJXI010000140         5115 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.148, whole genome shotgun sequence.
ACCESSION   DAMJXI010000140 DAMJXI010000000
VERSION     DAMJXI010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5115
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.148"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(478..2613)
                     /gene="rnr"
                     /locus_tag="PC465_003681"
     CDS             complement(478..2613)
                     /gene="rnr"
                     /locus_tag="PC465_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HDF2650946.1"
                     /translation="MIPGLKESLLGLINESAYNPLKKEELAEIFDIHSSEMPMFYNFL
                     NELEEDGYICFTKKGKIVSPNQMGYFVGKFVSHKKGFGFVESDVEYTQDLFISSDNIN
                     GAMHNDRVMAEIVVPATEEKRAEGRIVKVIKREITRIVGTFQSSKTFGFVTPDNKKFT
                     KDIYIPKKHFSGAVDNDKVVCEITVWPQEDRKPEGKIIEILGQKGERGVEIDSIIREH
                     GLPEEFPKKVLQEAEAVAVEIPQEEIKRRRDLRDLNIFTIDGDDAKDLDDAISIEVLP
                     NGNFKLGVHIADVTHYVREKNKLDKEALKRATSVYLVDKVIPMLPKTLSNGVCSLNPF
                     EDKLTLSIFMEIDHKGNVVKHEICESVINSKARMTYTEVSDILEKDDEKLKKTFEHVV
                     EDFKNAEILARILMSRREKRGAIDFNFPEAKIILNGKGEVVDIKPYERRISNKIIEEF
                     MLISNETIAEHFYWMGIPFVYRIHETPSLEKMEELSKFISTFGYIIKGDKEEVHPKAL
                     QGIIEKIKGKKEEGAISTIMLRSLKQAKYSPECSGHFGLAAKFYCHFTSPIRRYPDLQ
                     IHRIIKESLNNKISGKRQEQLTTIVDYASVQSSEKERKAELAERDVHDFYKALYMKDK
                     VGQEFEGVVSSVTSFGIFVELDNTIEGLIRLANMNDDYYIYDESSYSVLGERTKKSYK
                     IGDLVKIKVESVNVDFKEIDFEIVEKIEE"
     gene            3209..3823
                     /locus_tag="PC465_003682"
     CDS             3209..3823
                     /locus_tag="PC465_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDF2650947.1"
                     /translation="MEEVIAKIITIENGFKEIENIAKKIVKNNDSKKCYYLSIYLYRS
                     EYYQVRELAVFILGFISVTISEALLFLKDNVSKDENWRVQEILAKSFDYYCSEVGYEK
                     ALPVIKEWLNSDSPNIKRAVTEGLRIWTSRDYFKSNPDVAISLLSSLKEDDSEYLRKS
                     VGNALRDISKKYPDLVKKELDSWDISNKKVEFVYKLASKCILAK"
     gene            3841..4203
                     /locus_tag="PC465_003683"
     CDS             3841..4203
                     /locus_tag="PC465_003683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2650948.1"
                     /translation="MKLRDEYTCPLELTHDMIKGKWKSIILWRLRIGPTSLSKLEKEI
                     NGINQKMLLEQLKELIEFGLVDKKTYEGYPLKVEYSLTPIRGKQILDALAIMQDIGIS
                     FMLDNGMEDILKEKGVLK"
     gene            4309..4806
                     /locus_tag="PC465_003684"
     CDS             4309..4806
                     /locus_tag="PC465_003684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HDF2650949.1"
                     /translation="MKVTSTGIVNGVIEDKYGKRGTQFNEGGMPTYSLPLKFEDAPKN
                     TVSFAVFLEDKDSVPVCGFAWIHWLAVNITKDELNENESVTATDFVQGTTSWHGKLGG
                     LDRLEASVYGGMAPPDRPHVYEIHVFALDTILDLEKGFYMNEFFKAIEGHVLDTFTLK
                     GSYSN"
BASE COUNT         1677 a          777 c          614 g         2047 t
ORIGIN      
        1 ttcaattagc cacttctatt aagcatttct caattactta tttttcaatt agccacttct
       61 attaagcatt tctcaattac ttatttttca attagccact tctattaagc atttcttaat
      121 tacttatttt tcaattagtc acttctatta aacatttctt aattatttat ttttcaatta
      181 gccacttcta ttaaacattt cttaattatt tatttttcag ttggcttttt ctattaaatg
      241 tttcttaatt acttatcttt cagttagctc tttctattaa acatttctca attacttatt
      301 tttcaattag ctactttcat taaatatttc ttaattattt atctttcagt taactatttc
      361 cattagatat ttctcaatta cctattttta tcatttattt tatagagtat tgtgcactat
      421 atatttatac atatcataaa tactacaact tgttatctct tattttagct gttttatcta
      481 ctcctctatt ttttcaacta tctcaaagtc aatttcttta aaatctacat taacactttc
      541 aacctttatc ttaacaaggt ctcctatctt atatgacttc ttagttcttt ctcctaaaac
      601 actataagaa ctctcatcat aaatatagta atcatcattc atatttgcaa gtcttatcaa
      661 cccttctata gtattatcta actcaacaaa tattccaaat gaagttacgc tagatacaac
      721 accctcaaat tcttgaccaa ctttatcctt catataaaga gccttataga aatcatgtac
      781 atctctttca gctaactctg cctttctttc tttctcggat gattgaacag atgcataatc
      841 cactatagta gtaagctgtt cttgtctttt tccacttatt ttattattta aagattcttt
      901 tattattcta tgaatttgaa ggtcaggata tcttcttatt ggtgaagtaa agtgacagta
      961 gaatttagct gctaatccaa aatgtccact acattctggt gagtacttag cttgttttaa
     1021 agaacgaagc attatagtac tgatagctcc ttcttctttt ttgcccttta ttttctctat
     1081 tataccttgt aatgcttttg gatgtacttc ctctttatca ccttttatta tatatccaaa
     1141 tgtagatata aacttactca attcttccat tttttccaaa gatggtgtct catgtattct
     1201 atacacaaac ggtattccca tccagtaaaa atgttcggca attgtctcat tacttataag
     1261 cataaattct tctattatct tattagatat tcttctttca tatggcttta tatctacaac
     1321 ttcgcctttt ccatttagaa ttatctttgc ctctgggaaa ttgaagtcta tagctcctct
     1381 tttttccctt cttgacataa gaatcctagc taaaatttca gcatttttaa aatcttcaac
     1441 aacatgttca aaagtctttt taagtttttc atcatccttt tctaatatat cagatacttc
     1501 tgtataagtc attctagctt ttgaatttat tacagattca catatttcat gtttaaccac
     1561 atttccttta tggtctattt ccataaatat agaaagagtt aacttatctt caaatggatt
     1621 taagctacat actccatttg aaagagtttt tggcaacatt ggaattactt tatctactaa
     1681 ataaactgat gtagctcttt ttaaggcttc cttgtcaagt ttatttttct ctcttacata
     1741 atgtgtaaca tcagctatgt gaactcctag tttgaagttt ccattaggta atacttctat
     1801 tgatatggca tcatctaagt cttttgcgtc atctccatct atagtaaata tgtttaaatc
     1861 tcttaaatct cttcttcttt ttatctcttc ttgaggaatc tcaacagcta cagcttctgc
     1921 ttcttgcaat actttctttg gaaattcttc tggaagacca tgttctctta ttatagaatc
     1981 tatttctacg cctctttcac ctttttgacc tagtatctct ataattttgc cttctggttt
     2041 tctatcctct tgtggccata ctgtaatttc acatactacc ttatcattat ctactgctcc
     2101 actaaaatgt tttttaggta tatatatatc tttagtaaat ttcttgttgt ctggtgttac
     2161 aaatccaaaa gttttacttg attggaaggt acctactatt ctagttattt ctctctttat
     2221 tacttttact attcttcctt ctgctctctt ttcttcagtt gcaggtacta ctatttctgc
     2281 cataactcta tcattatgca tagcaccatt tatattgtca cttgagataa ataaatcctg
     2341 tgtatattca acatcagatt ctacaaatcc aaaacccttt ttgtgtgata caaattttcc
     2401 aacaaagtat cccatttgat tgggagatac tatttttcct tttttagtaa agcagatata
     2461 accatcttct tctaattcat ttaaaaaatt ataaaacatt ggcatttctg atgaatgtat
     2521 atcaaatatt tctgctaatt cttctttttt tagaggatta tatgcacttt catttattaa
     2581 tcctagcaaa ctttctttaa gtcctggtat catttttccc tcctgtttta cttttcatta
     2641 tattattatt tatattgtct tttatatttc ttcagacaaa acatttttta cttatcacat
     2701 aattttctat atttccttat tattattaca agttaaaatt acttatttat atttttgatt
     2761 taatgtaagc tttgtcatac taacttcaaa caaattatga tgttttataa attatttgta
     2821 aatatcatta taattactta agttattctt tatcataatt gcttaaatta ctctttatca
     2881 cctaattata caccatcaaa taggattggt aaaatattca tctcatataa gtattactat
     2941 ataataattt attctattag tatactcaaa tcatgtaaaa tttatataac tcaattaatt
     3001 ttttaaatac aactttataa tataaaactt ataataaaag taaatttata tgttaaatga
     3061 ggttgatttt ttattatttt ttatttatgc tagtactaaa gacttgcaaa cgttttttga
     3121 caagtcttta ttttgtctaa attaaacaaa cttttttaca aataaataca taaaatttaa
     3181 actaatctat ttattggagg agataaaatt ggaagaagta attgcaaaaa ttattactat
     3241 agaaaatgga ttcaaagaaa ttgaaaacat tgctaaaaaa attgtaaaaa ataatgactc
     3301 aaaaaagtgt tattatctat caatctactt atataggtca gaatattatc aagtaagaga
     3361 attggctgtg tttatacttg gttttatatc agtaactatt tctgaagctt tgttattttt
     3421 aaaagataat gtgagtaaag atgaaaactg gagagtacaa gaaatactag ctaaatcatt
     3481 tgattattat tgcagtgaag taggatatga aaaggctctt cctgttataa aagaatggct
     3541 taattctgat agtccaaaca taaaaagggc tgtgacagaa ggtcttcgaa tttggactag
     3601 tagagactat tttaaatcta atcctgacgt tgctatatca ctactttcta gtttaaaaga
     3661 agatgatagc gaatacttga gaaagtctgt aggtaatgct cttagagata taagtaaaaa
     3721 atatccagat ttagtaaaaa aagaattaga ttcatgggat atatcaaata aaaaagttga
     3781 gtttgtatat aagcttgctt caaaatgtat cttggcaaag taaaatggag gtgaacttat
     3841 ttgaaacttc gtgatgagta tacttgccca ttagaactaa cacatgatat gataaaaggc
     3901 aaatggaaat ctattatatt atggagatta cgtataggac caacttcctt atcaaaactt
     3961 gaaaaggaaa tcaatggtat taatcaaaag atgttacttg aacaacttaa agaattaatt
     4021 gaatttggtc ttgtagataa aaagacatat gaaggttacc cacttaaagt tgaatactca
     4081 cttacaccta ttcgagggaa acaaatattg gatgctttgg ctataatgca agatatagga
     4141 attagcttta tgttggataa tggtatggaa gatattctta aggaaaaagg tgttttaaag
     4201 taaatagata cccacaaaaa agtaagtaat ttaccattat tttcaactgg tatataatta
     4261 aattatagat atattctatt aatttattat aataggaggt aaattattat gaaagtaact
     4321 agtacaggta tagtaaatgg tgttatagaa gataaatacg gtaaaagagg aactcagttc
     4381 aatgaaggtg gtatgcctac atattcacta cctctaaagt ttgaagatgc tccaaagaat
     4441 acagtatcct ttgctgtatt tttagaagat aaagactctg ttcctgtatg tgggtttgca
     4501 tggatacatt ggttagctgt aaatataaca aaagatgagt taaatgaaaa tgaaagtgta
     4561 acagctactg attttgtaca agggactact agttggcatg gtaaactagg aggtcttgac
     4621 agattagagg ccagtgtata tggtggaatg gctcctccag acagacctca tgtctatgaa
     4681 atacatgtat ttgcacttga tactatcctt gaccttgaaa aaggattcta tatgaatgaa
     4741 tttttcaaag ctattgaagg gcatgtttta gatacattta cactaaaagg aagttattct
     4801 aattaattag gttgactata gctaatcatt aattaaatgc tacatttaat tgatgattag
     4861 cttaattgtt attagaatat tttctgcact ttatcttaat atatatttta gttgactggt
     4921 attttaattt ctattagatt attatcaatt tatataaatt gattttaact taaaacttac
     4981 ttatctattt caatttctat tagaattatt attagactca ttaaaataaa agcattaata
     5041 taactaataa tatatgttaa attcattaac tctacatgaa gttttataat ctaaatgaaa
     5101 tacaataatc tgcat
//
LOCUS       DAMJXI010000141         4964 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.149, whole genome shotgun sequence.
ACCESSION   DAMJXI010000141 DAMJXI010000000
VERSION     DAMJXI010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4964
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.149"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     misc_binding    232..463
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            571..2052
                     /locus_tag="PC465_003685"
     CDS             571..2052
                     /locus_tag="PC465_003685"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HDF2650950.1"
                     /translation="MYYSSTRGTEEKVTASQAIIKGISSDGGLYVPSEFPNVKNELIN
                     LVNLTYSQIAFFVLSKFLCDFTEDEIKNCIENAYDEKFDCSSIAPLNKVNDTYFLELY
                     HGPTLAFKDMALTIMPHLLKTSIKKDNLEKDVVILTATSGDTGKAALEGFKDIDKIKI
                     IVFFPEDGVSPVQKLQMKTQTGKNTYVVGIKGNFDDAQSGVKKIFSDKEFNQKLLDNN
                     YILSSANSINIGRLLPQVAYYFYSYMKLVSNSEINLNDKINFVVPTGNFGNILAGYYA
                     KQMGLPINKLICASNDNNVLYDFFKTGVYDKNRTLKLTTSPSMDILISSNLERLLFEI
                     SNRNTDIVNKLLSDLSDKGVYKISDDMEKNLASFYGEYSNEEEVKSTINNVFKNYNYL
                     IDTHTAVAYNCYEKYKKETSDNTKTVIVSTASPFKFSEDVLKSIDCDFKDLDDFAIID
                     RLSSISKIDIPKPIKNLKNAEILHKDIYEKDELKLAIKKFLKV"
     gene            2062..2955
                     /locus_tag="PC465_003686"
     CDS             2062..2955
                     /locus_tag="PC465_003686"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HDF2650951.1"
                     /translation="MLEIIVPATSANIGPGFDCLGIALNIYNKFYVEEIESGLEIEGC
                     EDAYKNENNLVYTSMKYFFDRVKPEKIPAGIKIKIQSEVPICRGLGSSASCIVAGVIA
                     ANALSGANLDKNQLLNIASEIEGHPDNVAPAILGNMIVSVTDNENIHYDIIKIPEELK
                     FCAMIPNFKLSTEKARGVLPKEIPYSDGVFNVSRVALLISALLNKNFDLLKVACQDKL
                     HQDYRGTLIENYNDIVEKSEQLNSIGVFLSGAGPTIMSLIKENDDSFVDNMKNYLQKL
                     KSDWEIKELCCDSNGAVLNII"
     gene            3079..4140
                     /locus_tag="PC465_003687"
     CDS             3079..4140
                     /locus_tag="PC465_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitronate monooxygenase"
                     /protein_id="HDF2650952.1"
                     /translation="MIIKELIIRDLVAKVPIIQGGMGVGISRSSLAGAVAKLGGVGVI
                     SGVQIGYDEEDFETNTINANLRAIKKHISKAKEISNGGIIGINFMVAMKEYETYVKEA
                     VKAGVDLIISGAGLPNKLPSLVKGSNVKIAPIVSTAKAANVILKMWDRKEKTTADLIV
                     VEGPKAGGHLGYSNEELDNIDSIDYDKEFVEILKVANTYGEKFGRNIPVVAAGGITSS
                     SDVKKYIDMGASGVQVGTRFVATYECDAHENFKMAYINASEEDVHIVKSPVGLPGRAI
                     RNKFIEEVKINRPEIKKCYNCLIPCNPKETPYCISQALINAVKGDVENSLLFCGNDAY
                     KIDKLSTVEDVINELISEL"
     gene            complement(4295..4807)
                     /locus_tag="PC465_003688"
     CDS             complement(4295..4807)
                     /locus_tag="PC465_003688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HDF2650953.1"
                     /translation="MSDFKEILAEEIKNNPFGLIGKDWTLITAENEGKVNTMTASWGG
                     LGVMWGKDVAFVVIRPQRYTKEFIDNTDKFSLTFFDEDFRKELSYCGKVSGREEDKIS
                     QIGFNIEHLNDTPYFKESKMAIICKKMYSQKLEPQCFIAEGIDGRWYPQKDYHTLYIA
                     EITNVLVKED"
BASE COUNT         1852 a          609 c          765 g         1738 t
ORIGIN      
        1 taatattaca gatatttaat agttatcttt taattacttt cattaaaaac agcttcatca
       61 ctatgaaaat ctaggttttt aaacttttaa aaaagttaaa aaaatatttt tctaatactc
      121 aatttgatta caattttttt acaatttaaa aaatattttt tccaaatttt tatattaata
      181 cttgactttg tctgttttat aaactagaat aattaataat attaagaata ttgaaaggca
      241 ttgattagga agagtaaatc tgaatcgatt accagagaag gaaactacta gctgaaatgt
      301 ttccctaatt agaaggattg aaaactacct aggagcttct atccgaagtt atcttaatga
      361 ttttagtagg aatagacgtt tttattactt gcgttaaagt atcaagtgga ttttttaaaa
      421 tcaatttggg tggaaccgcg ggaaacagat tctcgtccct tttttaggga tgagggtctt
      481 tttttattac ctaaattcag tttttaaaat attctgtatc taatttaatt agctaattaa
      541 aaatttaaaa tatatggagg attataaaaa atgtattatt caagtacgag aggcaccgaa
      601 gaaaaagtaa ctgcatcaca agcaataata aaaggaatat caagtgatgg tggtctttat
      661 gttccaagtg aatttcccaa tgtaaaaaat gaacttataa atttagtaaa tttaacgtat
      721 tctcagatag cattttttgt acttagtaaa tttttatgtg attttactga agatgaaatt
      781 aaaaattgta tagaaaatgc atatgatgaa aagtttgatt gtagtagtat agctccatta
      841 aataaagtaa atgatactta tttcttagaa ctatatcacg gtccaacttt agcatttaaa
      901 gatatggcac ttactataat gcctcatctt cttaaaacat ctataaagaa agataattta
      961 gagaaagatg ttgtgattct tactgctaca tctggagata caggtaaagc tgcacttgag
     1021 ggatttaaag atatagataa aataaagata attgtattct tcccagaaga tggtgtaagc
     1081 ccagtacaaa aacttcaaat gaaaactcaa actggaaaaa atacatatgt agttggtata
     1141 aaaggaaatt ttgatgatgc acaatcaggt gtaaagaaga ttttttctga taaagaattt
     1201 aatcaaaaac tattggataa taattatata ttatcttctg caaattcaat taatatagga
     1261 agacttcttc cacaagttgc atactatttt tattcatata tgaaattagt tagcaatagt
     1321 gagataaatt taaatgataa aataaatttt gttgtcccaa ctggtaattt tggtaatatt
     1381 ctagctggat attatgccaa acaaatgggt cttccaataa acaaattgat atgtgcatca
     1441 aatgataata atgttcttta tgatttcttt aaaactggtg tatatgataa aaatagaaca
     1501 ttgaaattaa ctacttctcc ttctatggat atattaattt caagtaattt agaacgatta
     1561 ctgtttgaaa tatcaaatag aaatactgat attgtaaata agcttttatc agaccttagt
     1621 gataaaggag tctacaaaat aagtgatgat atggaaaaaa atttagcctc attctatgga
     1681 gaatattcaa atgaagaaga agttaaaagc acgataaaca atgtgtttaa aaattataat
     1741 tatttgatag atactcatac tgctgttgca tacaattgtt atgaaaaata taaaaaagaa
     1801 acttctgata acacaaaaac tgttattgta agtactgcaa gtccattcaa gttttctgaa
     1861 gatgttctaa agtctataga ttgtgatttt aaagaccttg atgactttgc tataattgat
     1921 agattatcaa gtatttctaa aatagatatt ccaaaaccta ttaaaaatct taaaaatgca
     1981 gaaatactac ataaagatat ttatgaaaaa gatgaattaa aactagctat aaaaaaattc
     2041 ttaaaggtat aggtgattat tatgttagag attatagttc ctgcaacaag tgctaatata
     2101 ggtccaggat ttgattgtct tggaattgcg ttaaatatat acaataaatt ttatgttgaa
     2161 gaaattgaaa gtggtcttga aatagaaggt tgtgaagatg cttacaaaaa cgaaaacaac
     2221 ttagtttata catctatgaa gtactttttt gatagagtta aaccagaaaa aatacctgct
     2281 ggtatcaaaa taaaaatcca aagtgaagta cctatatgta gaggtcttgg cagtagtgcc
     2341 tcttgtatag tagctggagt tatagctgca aatgctctat caggtgctaa tttagataaa
     2401 aatcaattac taaatatagc ttcagaaata gaaggtcacc cagataatgt tgctcctgct
     2461 attttaggaa atatgattgt atctgttact gataatgaga acatacatta tgatattata
     2521 aaaattcctg aagaacttaa attttgtgca atgataccta attttaagtt atcaacagaa
     2581 aaagctagag gtgttttacc aaaggaaata ccatattctg atggggtatt caatgttagt
     2641 agagttgctt tactaatatc tgccttacta aacaaaaact ttgacctact taaagtagct
     2701 tgtcaagaca aattgcatca agattataga ggaactctaa ttgagaacta caatgatatt
     2761 gttgaaaaat ctgaacaatt aaatagtatt ggagtatttt taagtggagc tggacctact
     2821 ataatgtctt taataaaaga aaatgatgat agttttgtgg ataatatgaa aaattaccta
     2881 caaaaactaa aatctgattg ggaaataaaa gagttatgtt gcgattctaa tggagctgtt
     2941 ttaaatataa tataattatc gtcttctata caaaatataa ctactctttt attataattt
     3001 gtagtataat aattaggact aggtaataat attaagtatt ataatctagt tctttaaaca
     3061 tgtttacatt gaggagggat tatcataaaa gagttaataa ttagagattt agttgcaaaa
     3121 gttcctataa ttcaaggtgg aatgggcgtt ggtatatcta ggtcatcact agctggtgca
     3181 gttgctaagc ttggtggtgt tggtgtaatt tctggagttc aaattggata tgatgaggaa
     3241 gattttgaaa ctaatactat aaatgcaaat ttaagagcta taaaaaaaca tatttctaag
     3301 gccaaagaaa tctcaaatgg tggtattatt ggtattaatt ttatggtagc tatgaaagaa
     3361 tatgaaacat acgtaaagga agctgttaaa gctggtgtag accttataat atctggagct
     3421 ggattaccta ataagctacc atcattagta aagggaagta atgtaaaaat agcacccata
     3481 gtttcaactg caaaagctgc taatgtaatt ttaaaaatgt gggatagaaa agagaaaact
     3541 actgctgact taatagttgt tgaaggtcca aaagctggtg gtcaccttgg atactctaac
     3601 gaggaacttg ataacataga ttctatagac tatgataagg aatttgttga aattttaaag
     3661 gttgcaaata cttatggaga aaaatttggt agaaacatac cagtagttgc tgctggtggt
     3721 ataacttcta gtagtgatgt taaaaaatat atagatatgg gtgcaagtgg tgtacaagtt
     3781 ggtacaagat ttgttgctac ttacgaatgt gatgcccatg agaactttaa aatggcatac
     3841 ataaatgcta gtgaagaaga tgttcatata gttaaaagtc ctgtaggtct tcctggacgc
     3901 gccataagaa acaaatttat agaagaagtt aaaataaatc gtccagaaat aaagaagtgc
     3961 tataattgtt tgattccttg taatccaaaa gaaactcctt actgtatttc tcaagctcta
     4021 atcaatgcag ttaaaggaga tgttgaaaat tcacttttat tttgtggaaa tgatgcctat
     4081 aaaattgata aattaagtac tgttgaagat gttatcaatg aattgatttc tgaattataa
     4141 tttaaagaaa actaaattaa gattttatca agctaaggag tttaaatacg ttatttatta
     4201 atctttataa acatatttat gtccttagct tttttgtgtc aatttacttt tatggaaatt
     4261 ttaatttaat tagaaatagt attaaccttt ataactaatc ttcttttaca agtacattgg
     4321 ttatttcagc tatatataaa gtatgataat ctttttgtgg ataccatctt ccatctatac
     4381 cttcagcaat aaaacattga ggttcaagtt tctgactata catttttttg catataatag
     4441 ccattttaga ttctttaaaa taaggtgtat catttaagtg ttctatatta aatccaatct
     4501 gtgatatctt atcctcttct ctaccagata cttttccaca atatgaaagc tctttacgaa
     4561 aatcttcatc aaaaaatgta agagaaaatt tatctgtatt atctataaat tccttagtat
     4621 aacgctgtgg tcttattact acaaaagcaa catcttttcc ccacataact ccaagccctc
     4681 cccagctagc agtcattgta ttcactttac cttcattttc tgctgttata agtgtccaat
     4741 ctttacctat caatccaaat ggattatttt taatctcttc tgccaaaatt tctttaaaat
     4801 cactcatatc tctaataacc tctcattctc ttatatttat attcctttta ttttcgtgat
     4861 aaattataaa tgaagtctag ttttgaaaat aaaatacttt tttaaatata ttattgcaaa
     4921 taagtaaata tatatataca ctcttatttt ttaatatatt taat
//
LOCUS       DAMJXI010000142         4719 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.151, whole genome shotgun sequence.
ACCESSION   DAMJXI010000142 DAMJXI010000000
VERSION     DAMJXI010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4719
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.151"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(1..765)
                     /locus_tag="PC465_003689"
     CDS             complement(1..765)
                     /locus_tag="PC465_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDF2650954.1"
                     /translation="MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIE
                     KISSIRRIYGGAVLARETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDIST
                     INILLAKLLAESNKKVTLVTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTI
                     EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFD
                     GNFKFAHLEDISSIITEKTPTPDIVDILSEFNVNVL"
     gene            1039..1713
                     /gene="fsa"
                     /locus_tag="PC465_003690"
     CDS             1039..1713
                     /gene="fsa"
                     /locus_tag="PC465_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDF2650955.1"
                     /translation="MQLILDTGNVEEIKELCTCLPIDGVTTNPSIVSKEKKNFKQLIN
                     EIGEIIGEDMPIHAQVLSTKYEEILEEALYISSLRKNIYVKIPVTQDGLRAIKDLHRK
                     GVKITATAIFTAHQGFLAAKAGANYIAPYVNRLDNISGDGVAMVSELIKIIDTYKMDT
                     KVLAASFKNAQQVIELMQHGVHSVTVPYDICKSMMNHPLTDWSVDKFIEDWENTFGKG
                     SKTNNI"
     gene            complement(1835..3229)
                     /locus_tag="PC465_003691"
     CDS             complement(1835..3229)
                     /locus_tag="PC465_003691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HDF2650956.1"
                     /translation="MGIILKPKQFYMTVIATIILYFSLNYSFNIKFSICLSFLTILIW
                     AVDSVEKTFVALFFVILAFIFNIAPIKVILQFLFTENFYIIILAYIITNAVTKTGVAK
                     IISEKLILNTVNTPKKMILLSYILGILLIFFIPQPFPRVILVSAFYKEFLKEQQITED
                     SKSILLFSIFTASTFTSMFFVNGDTLLNYVVLELGNCNINWGQWAFYMSVPTIITCFI
                     TYFLFTFVFKKELHSIKFISNENLEGNKLHFSYSNLKKEFNLLNKEQKHVFLCLGIMF
                     FMFLTQFIHNINTLIIMSICVLLLLLRKIVGFSTLKEINWKVLIFFIAAFSIGGVLKY
                     SGVVDIMGNYLIKFIPNSSEIISILFLITLTIILNICLGSAVTTSSVVIPLLGSLHIL
                     KENSVTLCLFVYIIVSIQYILPFHHATIMVGHGENLYNSKVIFKYGLTLIPLTYFIII
                     CITFPWWKFIGLET"
     gene            complement(3307..4653)
                     /locus_tag="PC465_003692"
     CDS             complement(3307..4653)
                     /locus_tag="PC465_003692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2650957.1"
                     /translation="MKDLTTGHEGKSIFFFAMPMLIGSLFQQLYNTADSIIVGRFIGK
                     EAMAAVSGANPIMFLLVAALMGVSLGFSILVSQFYGSGDLKKVKATIDTTYILLFIGS
                     ILISILGIVFGGPMLKLMNTPESVFAQSKLYLTIIFSGILFSAGYNSVSAILRGLGDS
                     VTPLYFLIIATILNIVLDLTFIVVLRMGVEGVALATIMAQAVSFIISIIYLNKKHEVL
                     KFKIKGIVYDNKIFKDGLRLGLPSGVQQMLFSIGNMALQFLVNSYGTSAMAAFGAGLR
                     IENFISLPIMNLGSAVSTFVAQNIGAGENERVKKGIRESIKMTLVLAVTVIALILLFR
                     ENLIALFNTDKDVIKIGSSYLFIIGPFFLFIGTSFVLSSAMKGAGDSMFALISSIVSL
                     WLGRLPASYMLSKFFGTDGIWMGIPFGWTLGLIVTVIYYKKGHWKTKAIVNHRINE"
BASE COUNT         1819 a          667 c          623 g         1610 t
ORIGIN      
        1 ttataaaaca tttacattaa attctgataa aatatctact atatcaggag taggcgtttt
       61 ttctgtaatt atagaactaa tatcttctaa atgagcaaac ttgaaatttc catcaaattt
      121 aaacttttta tcttccataa ctataaatac ttttttactt gaatttatta tagccttctt
      181 cgtaagacca tcttcaattt caaaagttgt aagtgaagag ttgaatacat ctactccaca
      241 acttcccata aaagtcttat caaacttata tttcgatata aactctatag ttggagtacc
      301 gacaaaaccg tctaaactga gatttaataa acctccagtg gaaattatat ttaaattatt
      361 tggttttgaa gtaactacat ttagtatatc cagcatattt gtaacaagtg ttactttttt
      421 attactttca gctaacaact tcgcaagcaa gatgttaatt gtagagatat ctaaaaatat
      481 agtttctcta tcttcaatta aattaaatgc tttttctgct attattttct ttgttggaat
      541 attaatttct tttctgtctt ttgtatcctg attttctagt gtttctctag ctagtacagc
      601 tcctccataa attcttctta ttgaagaaat cttttctata ttttttaaat cttttcttat
      661 acaatcttct gtaacattaa atttagaact gagctctttg acagtaactc taccttcttt
      721 ttttaggata tttaatatag cttggattct ttcttctgca aacattttct acctcttttc
      781 gcaatatagt attatagtaa atattataag ataaaataca atatatcaac tattttaaca
      841 tgaaatacaa aattaattta atataaaaag tatgtttttt ctaactatat atttagaatt
      901 tagtaaataa aaaaattata aaactaagaa ggaaaagtaa aacaataata aaaaataaaa
      961 aacaataagc aaaatgttga aaataatacc aaatcaatat ataataagaa taaagaaaga
     1021 ttaaaggggg atattttaat gcaactaatc ttagatacag gtaatgtgga ggagattaag
     1081 gagttatgta cttgtttacc aatagatggt gtaactacaa atccaagtat tgtttcaaaa
     1141 gaaaaaaaga attttaagca acttataaat gaaattggtg agattatagg tgaggatatg
     1201 cctatacatg ctcaagtgtt aagtacaaag tatgaagaaa tattagaaga agcattatat
     1261 ataagtagtt tgagaaaaaa tatatatgta aaaatacctg taacacaaga tggtttaaga
     1321 gctataaaag accttcacag aaaaggtgta aaaataactg ctactgcaat attcactgct
     1381 catcaaggtt ttttagctgc aaaggctgga gcaaattata ttgcacctta tgtaaatagg
     1441 cttgataata tatctggtga tggagtagct atggtttcag aacttataaa aataatagat
     1501 acttataaaa tggatacaaa agtacttgca gccagtttta aaaatgcaca acaagttata
     1561 gaattaatgc aacatggggt gcatagtgtt acagtaccat atgatatttg taaatctatg
     1621 atgaatcatc cattaactga ttggagtgta gataagttta tagaggattg ggagaatact
     1681 tttggaaaag gaagtaaaac aaataatatt tagtattatg gtaaaagagt agttttgtcc
     1741 aatttcacaa gaacttatat aaaaagatga aaatatgaat tttcttttta ataatttcgt
     1801 tattatctta agttaattca tattttcatc ttttttaggt ttctagtcct ataaatttcc
     1861 accaagggaa tgttatacat attattataa agtaggttaa aggaatcaaa gttaaaccgt
     1921 atttgaaaat aaccttgcta ttatacagat tttcaccatg accaaccatt attgtagcat
     1981 gatgaaatgg taatatgtac tgtatgctta ctataatgta gacaaataga cataaagtaa
     2041 cactattttc ctttagtata tgtaaacttc caagtaatgg tattactaca gatgatgtag
     2101 tgacagcact tccaagacat atattcaaga ttattgtgag agttatcaaa aacaatattg
     2161 aaataatttc tgaagagttt ggtataaact ttatcaaata atttcccatt atatctacaa
     2221 ctccagagta ctttaacact cctccaattg aaaatgctgc tataaaaaaa ataaggacct
     2281 tccaatttat ttcttttaaa gtactaaatc caactatttt tcttagtaat aaaagaagta
     2341 cacaaattga cattataatt aatgtgttta tgttatgtat gaactgagtt aaaaacataa
     2401 aaaacattat tcctaggcat aaaaatacgt gtttttgttc tttgtttagc aaattaaatt
     2461 ctttttttaa attagaatat gaaaaatgaa gtttattacc ctcaagattt tcattagaaa
     2521 taaattttat tgaatgcaat tcttttttaa agacaaaggt aaataaaaaa taagttataa
     2581 aacaagtaat tatagttgga acagacatat aaaaagccca ttgaccccaa tttatattac
     2641 aatttccaag ttctagtaca acataattta gaagagtgtc tccatttaca aaaaacattg
     2701 atgtaaaggt agatgctgta aatatactaa ataaaagtat agattttgaa tcttcagtta
     2761 tctgttgttc ttttaaaaac tccttgtaaa aagcagatac aagaataacc cttggaaatg
     2821 gttgtgggat aaaaaatatt aaaagtatac ctaaaatata cgataaaaga atcatttttt
     2881 taggggtatt tacagtattt aaaattaact tctcagaaat aatttttgcg acacctgttt
     2941 ttgtaactgc attagtaatt atgtatgcaa gaattattat gtaaaaattt tctgtaaata
     3001 aaaactgtaa aataaccttt attggtgcaa tgttaaatat aaacgctaga attacaaaaa
     3061 acaatgcaac aaaagttttt tcaactgagt ctacagccca tatcaagata gttaaaaaag
     3121 ataagcatat agaaaatttt atgttgaaac tgtaattaag agagaagtag agaattatgg
     3181 tagctataac agtcatataa aattgttttg gcttaagaat aatacccatt tttatattca
     3241 cctccataat ttattatatc ataatggagg tgaatacaat gaatgtgaat acattttata
     3301 aaaagattat tcattgattc tatgatttac aatagcttta gttttccaat gtcctttctt
     3361 atagtagata actgtaacaa taagacctaa agtccaacca aaaggaatac ccatccaaat
     3421 tccgtctgtt ccaaaaaatt tagaaagcat ataagaagct ggaagtcttc caagccataa
     3481 agatactatt gagcttataa gtgcaaacat ggaatcacca gcacctttca ttgcacttga
     3541 aagtacaaaa gaagttccaa taaataagaa gaatggtcct attataaata agtaagaaga
     3601 gccaatttta atgacatctt tatcagtatt gaatagagca attagatttt ccctaaatag
     3661 caaaattaaa gcaataactg taactgctaa aactaaggtc atttttatag attctcgaat
     3721 gcctttttta actctttcat tttctccagc acctatgttt tgagcaacaa aagtagaaac
     3781 agcagaacca agattcataa taggtaagct tataaaattt tctatcctaa gaccagcacc
     3841 aaaagctgcc atagcagatg taccataact attaactaaa aattgaagag ccatatttcc
     3901 aattgaaaac aacatttgtt gaactccact tggaagtcct aatctaagtc catctttaaa
     3961 tattttgtta tcatatacaa ttcccttgat tttaaattta agcacttcat gttttttatt
     4021 taaataaatt atacttatta taaatgatac tgcctgagcc attatagtgg caagtgcaac
     4081 gccctcaaca cccattctta gcacgacaat aaaagttaag tctaaaacta tatttagaat
     4141 tgtggctatt atcagaaaat aaagtggagt tactgaatct ccaagtcctc taagtattgc
     4201 acttactgaa ttatatccag cagaaaataa tattccacta aatattatag taagatacaa
     4261 ttttgattga gcaaaaacgg attctggtgt attcataagc ttaagcatgg ggccaccaaa
     4321 tactattcca agaatactta ttaatataga accaataaat aaaagtatat atgtagtatc
     4381 aatagtagct tttacctttt ttaaatctcc tgagccataa aattgtgaca ctaaaataga
     4441 aaatccaagg ctaacaccca taagcgctgc caccaataaa aacattatag ggttagctcc
     4501 agagactgcc gccattgctt cttttccaat aaatctacca actattatac tgtcagctgt
     4561 attgtatagt tgttgaaata aactaccaat aagcataggc atggcaaaaa agaatatgga
     4621 ctttccctca tgacctgtag ttaaatcttt caccttattc ctccaaataa aaaaattatt
     4681 aatttattat agtataatct taacataaac tttatatcc
//
LOCUS       DAMJXI010000143         4650 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.152, whole genome shotgun sequence.
ACCESSION   DAMJXI010000143 DAMJXI010000000
VERSION     DAMJXI010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4650
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.152"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            227..1039
                     /locus_tag="PC465_003693"
     CDS             227..1039
                     /locus_tag="PC465_003693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HDF2650958.1"
                     /translation="MADCNSCPSKGNCNSQSNCSIENNPNNKFGKIIGVMSGKGGVGK
                     STVTALLANKLNKMGYKVGILDSDITGPSIPRLMGVKNVKAYSDGSYIYPVENSNNIK
                     VMSINLMIDDENEPVVWRGPLLGGVVKQFYTDVLWEELDYLLIDMPPGTGDVALTVMQ
                     SIPISGIVMVSVPQDLVSMIVSKAVNMAKKMNINVLGVIENMSYIQCPDCSKKIKLFE
                     GESTEKFLDDLDLELLGELPMTKEIIDITHNGVTEISDDLDSILTNVVEKIK"
     gene            complement(1128..1319)
                     /locus_tag="PC465_003694"
     CDS             complement(1128..1319)
                     /locus_tag="PC465_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650959.1"
                     /translation="MERLMELIERKFLKDVELLELEDIENVIECKMTQPYNAHYNEYL
                     VKVKNGDEVEEYFVYLKHR"
     gene            1622..1828
                     /locus_tag="PC465_003695"
     CDS             1622..1828
                     /locus_tag="PC465_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2650960.1"
                     /translation="MFKKKSGYTFTNFLSKVRVEKSKKYILKKDLSTLDVAVLIGFNS
                     QNYYSIIFKKFNNFTPIEYKNIYN"
     gene            2137..3756
                     /locus_tag="PC465_003696"
     CDS             2137..3756
                     /locus_tag="PC465_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HDF2650961.1"
                     /translation="MNIVISLIGGLGLFLYGMSLMGEGLQKSAGDKLKKIIELLTSNV
                     VMGVLVGTVVTGIIQSSSATTVMVVGFVNAGIMNLSQAIGVIMGANIGTTVTAQLVSF
                     NLEGIAPIALGIGILFYLFTSNQKTKHLSEILIGFGILFTGMEFMKDAVAPLAEYKAF
                     TDALLYFSKNPVLGILAGFAITGIVQSSSASMGMLIALASQGILPLSSALPILYGDNI
                     GTCVTSLLSSVGASRNARRAAVMHLSFNVIGTIIFMLVLNKPISAIVTHFDPTDTARQ
                     IANAHTLFNLTNVIILLPFSKYIVKLANRLIPIKETESEIVNNTKYLDERMFSTPSIA
                     LGNTVQEVVRMGHKATNSLEHSIAGFLNKSNEDINKAFESEKVVNKLQKDILNYLLKL
                     SKEPLRDDERFRTDLLFNTVNDIERVSDHAENIAELAMSVKEMNISFSDSAIREIYEI
                     YNKTITNFKDALIVLDVKDFELANKVLEVENEVNYLEKTFRNSHMIRLNNGSCTIDAG
                     VLYLDLLTNLERISDHSTNIVKQVLKLKQKI"
     gene            4130..4324
                     /locus_tag="PC465_003697"
     CDS             4130..4324
                     /locus_tag="PC465_003697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2650962.1"
                     /translation="MINYMVEIIYSEKISEVENMLKIENIQYEFTSRDGFIFFGFYDM
                     TDAYRFETLCSDEKIRFKRI"
BASE COUNT         1743 a          537 c          632 g         1738 t
ORIGIN      
        1 tttctatata tttatatgac taagttctat aactaaattg aaataatcac tttttcaaga
       61 atgttataat ttttttattg tattcttttt gctatagtct atgaataaat caatagaaaa
      121 tcttctaagt tgcttttaaa taatgacttt atggttcaat tgtactaaaa tagtatatgt
      181 aggttacaaa taatctaata aatattaaag tttggaggta atagatatgg cagattgtaa
      241 ttcatgtcca tcaaagggaa attgtaatag tcaatcaaat tgttctattg aaaataaccc
      301 taacaataaa tttggaaaaa taattggtgt tatgagtggg aagggtggag ttggaaaatc
      361 aactgtaact gctttacttg ctaataagct aaacaaaatg ggatataagg ttggtatatt
      421 agactcagat ataactggac caagtattcc tagacttatg ggtgtaaaaa atgtaaaagc
      481 ttattctgat ggctcttata tttaccctgt agaaaactca aataacataa aagtaatgtc
      541 tataaacctt atgatagatg atgaaaatga acctgttgtt tggagaggac ctttacttgg
      601 aggggttgta aagcaatttt atactgatgt actttgggaa gaattagact atttattaat
      661 agatatgcct cctggtactg gagatgttgc cttaacagtt atgcaatcta ttcctataag
      721 tggaatagtt atggtttcag tacctcaaga tttggtatct atgattgtat caaaagctgt
      781 taatatggct aaaaaaatga acataaatgt ccttggagtt attgaaaata tgagttatat
      841 ccaatgtcct gattgttcta aaaaaatcaa gttatttgaa ggagaatcta ctgaaaagtt
      901 tttagatgat ttagacttag aacttttagg agaacttcct atgactaaag aaattataga
      961 tattactcat aatggagtta cagaaattag tgatgattta gattcaatat tgactaatgt
     1021 tgttgaaaaa attaaataaa taaaaatttt ataattttat atttatcaaa aaaagaggct
     1081 tgtatttatt ttataatcat acaaataaat ataaacctct tttatgttta tctatgtttt
     1141 aaatacacaa aatattcttc tacttcatct ccatttttta cttttactaa atattcatta
     1201 taatgagcat tatatggctg tgtcattttg cattctatta cattttctat gtcttctaat
     1261 tctaaaagtt ctacatcctt taaaaatttt ctttctatga gttccattaa tctttccata
     1321 atatatcctc acttccccta taattaagat aaactatata tcctcttaat acagagttta
     1381 tcttaattat attatatcca atatattaca gtttctaaca tcattcataa attattttaa
     1441 caaatagaga ttgatttttt aataaatatg ccttgataaa atgaaacata gaccaactct
     1501 tagttttatg taaagaaaac ttaaagaaaa ctatagatta tattcacaaa aattactcag
     1561 aagatataac agtaagtaat atatgtaatg aattacaact taataaaagt tgtttttttc
     1621 tttgtttaag aaaaaaagtg gatatacttt tactaatttt ttaagtaaag ttagagttga
     1681 aaaaagcaaa aagtatatat taaaaaaaga cttgtctact ttagacgttg ctgtactaat
     1741 tggattcaat agtcaaaatt actatagtat aatttttaaa aagtttaata actttacacc
     1801 aattgaatat aaaaatattt ataactaaaa aatatcattc taaaaagatg ttattttttt
     1861 acatattttt tacaattata gttaattctt tgttaaattg attgtacata aaatactaaa
     1921 aatctaagtt caagtattta aattgctata tatcataaat tttctaaaat taacaacaac
     1981 ttaaaaattt aacattctct taacgtatac ttaacaaaac attaatattt ttattgacaa
     2041 aatttgttat tctatattat ggaaacaata aattttagtt aataaagttt ataattcaga
     2101 taaaaaaatt attaatttct taagggagga aatatcgtga atatagtaat tagccttatc
     2161 ggtggacttg gactttttct ttacggaatg agtttaatgg gagaaggttt acaaaaatca
     2221 gcaggagaca aattaaaaaa aattattgaa ctcttaacaa gtaatgttgt tatgggtgta
     2281 ctggtgggta cagtcgttac aggtattata caaagttcaa gtgctactac tgttatggtt
     2341 gtaggatttg taaatgcagg tataatgaat ctaagtcaag ctattggtgt aataatgggg
     2401 gcaaatatag gtactacagt tactgctcaa ttagtttcat ttaatcttga aggaattgca
     2461 ccaattgctt taggtatagg tattttattc tatttattta catcaaatca aaaaacaaag
     2521 catttatctg agatacttat aggtttcggt atattattta caggaatgga gtttatgaaa
     2581 gatgcagtag ctccacttgc tgaatacaaa gcattcactg atgcactttt atattttagt
     2641 aaaaatcctg tattaggtat attggcagga tttgccataa ctggtattgt tcaaagttca
     2701 agtgcatcta tgggtatgtt aatagcacta gcttctcaag gaatacttcc tctatcatct
     2761 gctttaccta ttctttatgg agataatata ggtacttgtg ttacttcact tttatcaagt
     2821 gttggtgcaa gtagaaatgc tcgacgtgca gctgtaatgc atttaagttt taatgtaatt
     2881 ggtacaataa tatttatgct tgttttaaat aaacctatat cagccatagt tactcatttt
     2941 gacccaactg atacagctag acaaatagca aatgcacata ctttatttaa tcttacaaat
     3001 gttataatat tattaccatt ttctaaatac atagttaaat tagcaaatag acttatacct
     3061 attaaagaaa ctgaatcaga aatagtaaat aatactaagt acttagatga aaggatgttt
     3121 agcactccat ctatagcact tggtaatact gtacaagaag ttgtaagaat gggtcataaa
     3181 gctacaaact ctttggaaca ttcaattgca ggatttttaa ataagagcaa tgaagatatt
     3241 aataaagctt ttgagtcaga aaaagttgtc aataagttac agaaagatat attgaactat
     3301 ttgttaaaac tttctaaaga acctcttaga gatgatgaac gctttagaac agatttgctt
     3361 tttaatactg taaatgacat tgaaagagtc tctgaccatg cagaaaatat agctgaattg
     3421 gccatgagtg ttaaggaaat gaacattagt ttttctgata gtgcgataag agaaatatac
     3481 gaaatataca ataagacaat tactaatttt aaggatgcct taatagtttt agatgttaaa
     3541 gattttgagt tagcaaataa agttttagaa gttgaaaatg aagtaaatta tttagaaaaa
     3601 acttttagaa attcacatat gattagacta aataatggaa gttgtacaat tgatgctggt
     3661 gtactttatc ttgacttact tactaatcta gaaagaattt ctgaccactc aacaaatata
     3721 gtaaaacaag tactaaaact taaacaaaaa atatagtgat tatttttata tataatctta
     3781 atcaatgaga agtaagaagc tatagataat gcttatatca tttatggctt cttatttttt
     3841 atgtaatact caaattttta tagtattctc ttattattaa acagtttctg cctagaatat
     3901 tccatatata tatgacttct ttcataaaac ttgaactgcc cataaataaa gtcacaagta
     3961 tacataacta ttttttaatc aattataacc aatatttgtt ttatttatct tcattttaat
     4021 tcttcattca ataatgtaat aagattattt tttatttgga tactattata tcatctaaat
     4081 atgttattat atatttggat attttcatat taataggagg gattctacaa tgataaatta
     4141 tatggtagaa attatatata gcgaaaaaat aagcgaagta gaaaacatgt tgaaaattga
     4201 aaatatacaa tatgaattta cttctcgtga tggctttata ttttttggtt tttatgatat
     4261 gacagacgca tatagatttg agactttatg ttcagatgaa aaaattcgat ttaaaagaat
     4321 ataatagata aaaaagtaca tatttctaaa ctatttgttt ttcaaattta ggttgtgttt
     4381 taatgtagtg ttgatattat aaacaatttt aataataaaa aagtagggac attatattaa
     4441 tatgctccta ctttttactc atacttatta atattattta tcaaaattac cctacaaact
     4501 ggaatttatc attctttcat aattttaaac tatcatattt aaaatatata aaattctaca
     4561 tgatttttgt ataaacataa tatcaaccat tatccaattt aaaaatattt tttagtaatt
     4621 tccatttcat tttctcttaa catattaatt
//
LOCUS       DAMJXI010000144         4508 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.153, whole genome shotgun sequence.
ACCESSION   DAMJXI010000144 DAMJXI010000000
VERSION     DAMJXI010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4508
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.153"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            105..773
                     /locus_tag="PC465_003698"
     CDS             105..773
                     /locus_tag="PC465_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650963.1"
                     /translation="MENITSYFTTILCVFICLSSVFIFTQLARVFINKKKINQKIKSR
                     NGFRYDRDFIEARREEIHIKDNNNNKNKSNNKKLKGEKVFKYDNGDLYKGEFVDGKKN
                     GFGIYIFSSKEKYEGLWKDDKMHGIGKYTYRDGSIYTGEFKYGLKNGLGKLTYPNNDI
                     YKGYFLDNKKNGKGVLYKNDGNKQAGIWEDDEQCKSLDFKDLNNNKINNVYQNRLNNN
                     KLKV"
     gene            932..1438
                     /locus_tag="PC465_003699"
     CDS             932..1438
                     /locus_tag="PC465_003699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HDF2650964.1"
                     /translation="MKEYVVVDLETTGLDPYKGCEIIEIGITEIKNEQIVKNYSRLIK
                     PKGIISSFITELTHISNEMVENEEPLELVLPRFRKYIGDRTIIAHNAKFDLKFLNYYL
                     RMLDLEPINNYICTVELLKKCKSYKGKNKKLETACAYYNIENINAHRADSDTLATAKL
                     FLKIKDEY"
     gene            1566..2582
                     /locus_tag="PC465_003700"
     CDS             1566..2582
                     /locus_tag="PC465_003700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HDF2650965.1"
                     /translation="MGYYNDNDNNKIRRKKISNNKDSNKKSKHSYTLANKKNKSPNTS
                     SSKRMSEKVDSQNLIKRDRDSFTRDNVRPLNTDYNQRERRRVEYKQREKKLKSKKRKK
                     QKRIRIVRALLSIMLVALIIFSVAGAIFTVSAIKGSPEVTKKLIRSKYISSEVVSIKQ
                     MPNDLKHAIVSIEDERFYKHKGVDVISLVRSVLNNVFTDTTQGASTIDMQVSKNLLTS
                     NDKTMKRKIRDMYNAKQMNKIMTKDEILEAYLNNMYLGKNAYGAAKGAEVYFGKKVSE
                     LNLAECAMLAGMTNNPARYIDHGEAKKRQVIVLYKMHQLGYITDKEYRIAKADDTPFK
                     SEID"
     gene            2935..3639
                     /locus_tag="PC465_003701"
     CDS             2935..3639
                     /locus_tag="PC465_003701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HDF2650966.1"
                     /translation="MKKFVIEDAFWNLFPSAKIGVVICNDIDNSIKDEDYKKIILKGE
                     EEALKYLGDSEFSNNQVIKVWREAFKKFKTKKGARSSIEALLKRVHNGNNIGTINPLV
                     DIYNFISLKYALPCGGEDIDKFIGDIRLTRAIGNEEFIPLGTDENSFPYEGEIIYKDD
                     GGAICRCWNWREAVRTMLTEDTNNAFLCIELVDESRFKEFENALNELAKIVQEKLGGN
                     CKISILDIDNKEVSVD"
     gene            3934..4413
                     /locus_tag="PC465_003702"
     CDS             3934..4413
                     /locus_tag="PC465_003702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HDF2650967.1"
                     /translation="MSNKLIKNLLSGILQILFFLLGLVIVAGGFKSFMYLCFSGEATL
                     QGTIYGILMFILGVSYFIIIKSLIEVLGSSEYSLFVKENVKRFRIIGYLLLLNSLIEF
                     ISTFGTTGKGMRFLDLGFGFYFTVPVFVYFITSLMSFVIADGFVKAIKIKEDNDLTI"
BASE COUNT         1891 a          375 c          766 g         1476 t
ORIGIN      
        1 agttaatttt attcaatata gtactataaa agtataaata acatttaata aaaatatata
       61 ttatattagg tattttaaat aaatttttta aagggtgatt ttttatggaa aatataacta
      121 gttattttac aacaatacta tgtgtattta tatgcttatc atctgtattt atatttactc
      181 aactagctag agtatttatt aataagaaga agattaatca aaaaattaaa tcaagaaacg
      241 gatttaggta tgatagagat tttattgaag ccagaagaga agaaatacat ataaaggata
      301 acaataataa taaaaataag agtaacaata agaaattaaa gggagaaaaa gtatttaaat
      361 acgataatgg tgatttatat aaaggtgagt ttgttgatgg aaagaaaaat ggatttggaa
      421 tatatatttt ttcaagtaag gaaaagtatg aaggattatg gaaagatgac aagatgcatg
      481 gaataggaaa atatacttat agagatggtt caatatatac aggtgaattt aaatacggat
      541 taaaaaatgg tttgggaaaa ttaacatatc ccaataatga catttataag ggatattttt
      601 tagataataa gaaaaatggt aagggtgtat tatataaaaa tgatggaaat aaacaagcag
      661 gaatatggga agatgatgaa caatgtaaaa gtttagattt taaagattta aataataata
      721 aaataaataa tgtttatcaa aatagattaa ataacaataa attaaaagtt taattattct
      781 aataaaaaaa tctttattta tgatggaata taggatatat ctatgttgta atttgtaaaa
      841 tcttcctata tcatataaaa ttaagtattg attagtctat tacataaata tagaatataa
      901 atatatccat ttaataataa ggagaagaga tatgaaagag tatgtagttg tggatttaga
      961 aactacagga ttagatccat ataaaggttg tgaaataata gaaataggaa taacagaaat
     1021 aaaaaatgaa caaattgtaa aaaactattc aaggttgata aaacctaagg ggataatttc
     1081 ttcatttata acagaattga cacatataag taatgaaatg gtagaaaatg aagaaccact
     1141 agaattagtt ttacctagat ttagaaaata cataggtgat agaactataa ttgcacacaa
     1201 tgcgaaattt gatttaaaat ttttaaatta ctatcttaga atgttagatt tagaaccaat
     1261 aaacaattat atatgtacag tagagttatt aaaaaaatgt aaaagttata aaggaaaaaa
     1321 caagaaactt gaaacagctt gtgcttatta caacatagag aatataaatg ctcatagagc
     1381 tgacagtgat acattagcaa ctgcaaaact atttttgaaa ataaaagatg aatattaatt
     1441 ataaatatag agaaaattag tgaaaatatc ctttataaaa ttgaccctta agcttacaat
     1501 tttgttcttt gatttatttt gtagaacaat gtataatgta ccttatatga agaagggaga
     1561 ctaaaatggg ttattacaat gataatgata ataataaaat aagacgtaaa aaaattagta
     1621 acaacaaaga tagtaataaa aaatctaaac attcttatac tttggcaaat aaaaaaaata
     1681 aaagtcctaa tacaagttcc agtaaaagaa tgagtgaaaa agtagattca cagaatctta
     1741 taaaaagaga tagagatagt tttacaagag ataatgtaag acctttaaat acagattaca
     1801 atcaaagaga aagaagaaga gtcgagtata aacaaagaga gaaaaaatta aaaagtaaaa
     1861 aaagaaaaaa acaaaaaagg attagaatag ttagggcatt attatctatt atgttagttg
     1921 cactaattat attttcagtg gcaggtgcaa tatttacagt ttcagctata aaagggtcac
     1981 cagaagttac taaaaagtta attaggtcta aatatataag tagtgaggtt gtaagtataa
     2041 aacaaatgcc aaatgattta aaacatgcaa tagtttccat agaagatgag agattttata
     2101 agcataaagg agtagatgtt atttctctag ttaggtcagt attaaacaat gtgtttacag
     2161 atacaacaca aggtgcaagt actatagata tgcaagtttc aaaaaacctg cttactagta
     2221 atgataaaac tatgaagcgg aaaataaggg atatgtataa tgctaagcag atgaataaga
     2281 ttatgactaa ggatgaaatt cttgaagcat atttaaataa tatgtatcta ggtaaaaatg
     2341 catatggagc tgcaaaggga gctgaagtct actttggtaa aaaggttagt gaattaaatt
     2401 tagctgagtg tgctatgtta gctggtatga caaataatcc tgcaaggtat attgaccatg
     2461 gagaggctaa gaagagacaa gtgattgtgt tgtataagat gcatcagctt ggttatataa
     2521 ctgataagga gtatagaata gcaaaagctg atgacactcc atttaaatca gaaattgatt
     2581 aaaattgtaa gaatatagta tttcaatagt ttaaacaaac gaaaatgtaa taaaaaaggt
     2641 gatttgccac ccatttgcca ccataattat aatttaatag caaattgttt taatgtacaa
     2701 atccgataat ataatattgt tttaaatact acattatgct aaaatttaat tgtattttgt
     2761 aaattaaaaa acttataatt tagttttcta gggttccgca ttttataatg gtcaggtcca
     2821 agagaaaacg cacaattgtt gtgtacacgg aaggataaaa gcctgggaga tatttaataa
     2881 tatttctata ggctttttta tttttacata ttttaaattt gaggaggttt tctaatgaaa
     2941 aaatttgtta ttgaggatgc attttggaat ctatttccta gtgcaaaaat tggagttgtt
     3001 atttgtaatg atatagataa ctctataaaa gatgaagact ataagaaaat aattttgaag
     3061 ggagaagaag aagcattaaa atacttgggg gactcagaat ttagcaacaa ccaagtgatt
     3121 aaagtatgga gagaagcatt taaaaaattt aaaacgaaaa aaggagcaag gtcttctatt
     3181 gaagcattat taaaaagagt tcataatgga aataatatag gaactattaa ccctttagtg
     3241 gatatctaca attttatctc attaaaatat gcattacctt gtggagggga ggatatagat
     3301 aaatttatag gagatattag gctaactaga gcaattggta atgaggagtt tatcccacta
     3361 gggacagatg aaaattcatt tccatatgaa ggagaaataa tttataaaga tgatggtgga
     3421 gcaatttgta gatgttggaa ttggcgtgaa gcagtgagaa caatgcttac tgaagatact
     3481 aacaatgcct ttttatgcat tgaattagta gatgaaagta gatttaaaga atttgaaaat
     3541 gctttaaatg aattagctaa aatagttcaa gaaaaattgg gtgggaattg taaaatttca
     3601 attttagata ttgataataa agaggtatca gtggattaat atggaggtgc tgttgtaatg
     3661 gactattcta gttataaaga tacttatatt tagggtaaga aggtctattt tagatataac
     3721 gattatcaaa ggatataata tagaaaataa aaatgtagaa tataaaaagc ctttaaaata
     3781 agaaaaaaat gtattttaaa ggcttttatt atactctttt ttatttgcat aattaacaat
     3841 aaaaatatat tgttaattat aatattttta ttgaaaaacg atataatata atgtattata
     3901 ctatatataa aatattttaa aggagttggc atgatgtcta ataaacttat aaaaaattta
     3961 ctaagtggta tattacaaat tttatttttt cttttaggat tagtaattgt tgcaggagga
     4021 tttaaaagtt ttatgtacct ctgttttagt ggagaagcaa ctctacaagg tactatttat
     4081 ggaatattaa tgtttatttt aggtgtatca tattttatca ttataaaatc attgatagaa
     4141 gtattaggta gttctgaata tagcctattt gtaaaagaga atgtaaaaag atttaggatt
     4201 attggatatc ttttgctttt aaactctcta attgagttta tttcaacttt tggtactact
     4261 ggaaaaggaa tgagatttct agatttagga tttggatttt attttactgt tccagtattt
     4321 gtatatttta taacttctct gatgagtttt gtaattgcag atggatttgt aaaggcaata
     4381 aagataaaag aggataatga tttaactatt taggtgtgac actttaatat ataggagata
     4441 aataacccga aaagagtgat taactagtaa tttaaaatat attagggtat aatacataaa
     4501 ctataatg
//
LOCUS       DAMJXI010000145         4446 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.154, whole genome shotgun sequence.
ACCESSION   DAMJXI010000145 DAMJXI010000000
VERSION     DAMJXI010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4446
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.154"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            276..1751
                     /locus_tag="PC465_003703"
     CDS             276..1751
                     /locus_tag="PC465_003703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HDF2650968.1"
                     /translation="MDSEFANVVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGV
                     AILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQA
                     IHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKV
                     RTEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLP
                     PSAISLGADMVAVSIHKTGGALTQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMA
                     SIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKL
                     CINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIA
                     KIYRKESTLNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIP
                     IIAPGELITEEIMEYIIFLKNSNAYLTDVQDKNLDRILVIK"
     gene            1838..2251
                     /gene="speD"
                     /locus_tag="PC465_003704"
     CDS             1838..2251
                     /gene="speD"
                     /locus_tag="PC465_003704"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HDF2650969.1"
                     /translation="MKFETLGRHILVEYYNCDENVLKDPRLIENFMNDSALNAKATIV
                     DSVFHHFNPWGVSGAVIIAESHLTIHTWPEYGYAAADFFTCGDIDPWKSFELLEQLLK
                     SERSESTEIPRGLTTKIKKYSKKDLGKITHKPEAV"
     gene            2281..3132
                     /gene="speE"
                     /locus_tag="PC465_003705"
     CDS             2281..3132
                     /gene="speE"
                     /locus_tag="PC465_003705"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HDF2650970.1"
                     /translation="MELWYTEEWTENVRFSIKVNKHLFEGKSQFQRIDVFDSDEFGKF
                     LTIDGLMMVTYKDEFIYHEMITHVPMATNLNIKKVLVIGGGDGGTVRELSRYPQIEKI
                     DMVEIDKMVVDVSKEYMDICSCKLDDKRVSLYFEDGVNFVKCAHDKSYDLIIVDSTDP
                     IGPGEGLFSTDFYKDCYRILTDDGILVNQSESPYFDFNAKEMKRANKKLKQIFPISEV
                     YQAHIPTYPSGHWLFGFASKKLNPVKNQDRNGWEKLSLKTKYYNSDIHLGSFMLPQYV
                     KEMLDEE"
     gene            3122..4000
                     /gene="speB"
                     /locus_tag="PC465_003706"
     CDS             3122..4000
                     /gene="speB"
                     /locus_tag="PC465_003706"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HDF2650971.1"
                     /translation="MKNNFYHMNTFMSMDKNYEESNLIVFGVGFDGTTSNRPGARFAS
                     SSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSK
                     VPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
                     VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDV
                     LDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIA
                     CKILRELCLIISDKIK"
     gene            complement(4180..4380)
                     /locus_tag="PC465_003707"
     CDS             complement(4180..4380)
                     /locus_tag="PC465_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF2650972.1"
                     /translation="MKNGIVKWFNNEKGFGFISVEGEDDVFVHFSAIQNDGYKTLEEG
                     EKVSFDITQGNRGPQAENVNRI"
BASE COUNT         1769 a          498 c          759 g         1420 t
ORIGIN      
        1 aaaagtaaaa aaaccaaaat aataaaaaat aagaaagttt ataaatacta agttttaaaa
       61 aaattaatat aaacaacaaa aaattaaaaa gtttataaat attgatatag ctaatgtata
      121 tgtttttgag taacttcaaa aaaacacttg taaaaatgct gagatgttaa tataataaat
      181 atcatgagtt taataaaagt aaaaataaaa aatagaaata ataaataata aatattaaaa
      241 atatttgaat atagagagga gatgaatttg aaatcatgga tagcgagttt gcaaatgtag
      301 ttgaattaag ctatgagtgt gctccattat tagagtcgtt aaaggaatac tcagagaaag
      361 atatagcttg ttttgatgtg cctggacatg taaaaaatag aggtgtagct atattaaata
      421 aatatctagg tgaaagtctc atgaaaatgg atataaattc atcaccaact atggataatg
      481 tatctgcgcc aaatgggatt ataaaaaatg cacaagattt gttagcacaa gcatatatgg
      541 ctgatgaggc attctttata acgaatggca caactcaagc aatacatgca atgattttga
      601 gtgttataaa accaggtgaa aaagtattac ttccaagaaa catacataaa tcagtaataa
      661 atgcgttaat actttgtgga ggaataccaa tatttataca accagaattt gatgaaaaac
      721 taggtataag tttaaatatt actcttgaaa aagttagaac agagatagaa aaagattgta
      781 atataaaagc attatttttc cttaatccaa cttactatgg agtttgtgca gaccttgaga
      841 gtattataga actatgccat aaaaataatg ttttagtgtt agttgatgaa gctcatggtg
      901 cacattttcc atttcattta gatttacctc cttctgcaat aagtttggga gctgatatgg
      961 tagctgtaag tatacataaa actggaggag cattgacaca atcttcagca ctcttattga
     1021 atagagataa tgtaagtttt gaaaaggttc ttcaatcaat caatatgcta caatcaacat
     1081 cagcatctta tttgcttatg gcaagtatag atggtgctag agttaatcta gttgagaatg
     1141 gtgaaaagca actgtcaaaa gcattaaatc tatctaggta tgcaaaatct aaattaaaca
     1201 aaattgatgg aataaaagtt ttatctacag aaatattgaa acaaaaaggt gttaaattta
     1261 tagatgaaac aaaattgtgt ataaatgtaa aagaattaaa tttgactgga tttgaagtat
     1321 acgatttatt atataaaaat ttttcaattc aagtagaatt gggagattca tataatatac
     1381 tggcacttgt gtccattgga acaaataaat cagatataga tagattagta aaggcacttt
     1441 ctataattgc aaagatttat agaaaagaat caacattaaa tgaatttaat atggttcaaa
     1501 taaatccaat tattaaactt aatccaagag aagcttttta tgcaccaaag gaaagtgtag
     1561 aaatcaattc atgtatagat agaatttgtg gagaatcaat aatggcatat ccaccaggta
     1621 taccgattat tgctccagga gaattgataa cagaagaaat tatggagtat attattttct
     1681 taaaaaatag caatgcgtat cttacagatg tacaagataa aaacttagat agaatactag
     1741 taataaaata aattacttta ttttgcaagg gcaagtattt gttaagtaga gtttatcaaa
     1801 tagaacttat taaaagtata aaggagttgg ggttgaaatg aaatttgaaa cactaggaag
     1861 acatatacta gtagaatact ataattgtga tgaaaacgta cttaaagacc cacgtcttat
     1921 agaaaatttt atgaatgatt cagcattaaa tgcaaaagcg acaattgtgg attctgtatt
     1981 ccaccatttt aatccttggg gggtttcagg agctgttata attgctgaat ctcatttgac
     2041 aatacataca tggcctgaat atggttatgc agcagcagat ttttttactt gtggtgatat
     2101 agacccatgg aaaagttttg aattattaga gcaactttta aagtctgaaa gaagcgagtc
     2161 tacagaaatt ccaagaggct taactacaaa aattaaaaaa tattcaaaaa aagatttagg
     2221 taagattact cataaaccag aagcagtata aaacatacaa gagaaagtga ggattattat
     2281 atggaacttt ggtatacaga agaatggaca gaaaatgtaa gattttctat aaaagtaaat
     2341 aaacatctat ttgaaggaaa gtctcaattt caaaggatag atgtatttga tagtgatgaa
     2401 tttggaaaat ttctaacaat agatggatta atgatggtaa catataaaga tgaatttata
     2461 taccatgaga tgataactca tgttcctatg gctacaaatt taaacataaa gaaagtatta
     2521 gtcataggtg gaggtgatgg aggtacagta agagaattaa gccgttatcc tcaaatagaa
     2581 aagattgaca tggttgaaat agataaaatg gttgtagatg tatctaagga gtatatggat
     2641 atatgctcat gtaaattaga tgataaaaga gtgagtttat attttgaaga tggtgttaat
     2701 tttgttaagt gtgcacatga taaatcatat gacctgataa tagtagattc aactgaccca
     2761 ataggaccag gcgaagggct tttctcaact gatttttata aggattgtta tagaatactg
     2821 actgatgatg gaattttagt aaatcaaagt gaaagtccgt attttgactt taatgctaaa
     2881 gagatgaaaa gagctaataa aaaattaaaa cagatatttc caatatcaga agtttatcaa
     2941 gcacatatac caacatatcc atctggtcac tggttgtttg gatttgcttc aaaaaaactt
     3001 aatccagtaa aaaatcaaga tagaaatgga tgggagaaat taagtttaaa aactaaatat
     3061 tataatagtg atatacattt aggttcgttt atgttacctc aatacgtgaa ggagatgcta
     3121 gatgaagaat aatttctatc atatgaacac ttttatgagt atggacaaaa attatgaaga
     3181 atctaatctt atagtatttg gtgttggatt tgatggaact acttctaaca gacctggggc
     3241 tagatttgca agtagctcta tgagaaaaga attttacggt cttgagacat atagtccttt
     3301 tttagatttg gatttagagg attataatat atgtgattat ggagatttag aaattagtgt
     3361 tggaagtaca gaacaagtct taaaagaaat ctatcaagag acatataaga ttgttagaga
     3421 ttcaaaggta ccctttatga ttggaggaga gcatttagtt acattaccag cctttaaagc
     3481 agtacatgaa aagtacaatg atatatatgt aattcatttt gatgcccata ctgatttgag
     3541 ggaagaatat aataatagta aaaattctca tgcaacagta attaaaagaa tatgggatat
     3601 tgtaggtgat aataaaatat ttcaatttgg tataaggtct gggacaaaag aagaatttaa
     3661 atttgctaca gaagaaaaac acacatacat ggaaatagga ggaatagata cgtttgaaaa
     3721 tatagttaat atgctaaatg gaaagaatat ttatctaact atagatttag atgtattgga
     3781 tgcatctgtg tttccaggaa caggtacacc agaacctggt ggtgtaaatt atagagagtt
     3841 tcaagagatt tttaagatta taaaaaactc taatataaat atagttggtt gtgacattgt
     3901 agagttaagc cctgattacg atacaacagg tgtatcgaca gttatagctt gtaaaatctt
     3961 aagagagtta tgcttaataa tatctgataa aattaaatag agtattttat ataaatagta
     4021 tatattataa tataagaagt tattttaaaa aagttagttt aagtttgacg cttttctaaa
     4081 gtaacttctt atttttgtaa ttaaaaataa atataataaa caacaaaaaa gagccctcga
     4141 tagctccttt tctaaaatat atatatttaa attaaataat tatattctat ttacgttttc
     4201 agcttgaggt cctctattac cttgagttat atcaaagcta accttttcgc cttcttctaa
     4261 agttttgtat ccatcatttt gtatagctga gaaatgtacg aaaacatcat cttctccctc
     4321 tacagatatg aacccaaatc ctttttcatt gttaaaccat tttactattc cgtttttcat
     4381 tataagaaaa cctccgcatt attaaaaaat acaaactaaa aaaataagtc tgttctatta
     4441 atataa
//
LOCUS       DAMJXI010000146         4435 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.155, whole genome shotgun sequence.
ACCESSION   DAMJXI010000146 DAMJXI010000000
VERSION     DAMJXI010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4435
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.155"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            45..344
                     /locus_tag="PC465_003708"
     CDS             45..344
                     /locus_tag="PC465_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650973.1"
                     /translation="MKWIKWYSITCICIFIVVAFYMFIFPNKIETIDTSSAYSFVEKK
                     VPNSAVYQGYKKNPVDGTTTIYYSYDNSTHIVRLSHPEDYSRKINWDKVSNIRFD"
     gene            685..2340
                     /gene="ilvD"
                     /locus_tag="PC465_003709"
     CDS             685..2340
                     /gene="ilvD"
                     /locus_tag="PC465_003709"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020457899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HDF2650974.1"
                     /translation="MRSDIKKGIEGAPKRALMYGMGLTKEEIERPLIGIVNAQNEVIP
                     GHLHLDEIAEAAKNGVRMSGGLPLEFPAIGVCDGIAMGHVGMNYSLASRELIADSIEA
                     MAMAHGFDALVLIPNCDKIVPGMLMAAARLNIPSIVVSGGPMLPGKKNGKVYDFNSAM
                     EGVGACKDGIVSEEELEALAMNSCPGCGSCSGLFTANSMNCLTEALGMGIPYNGTAAS
                     HSGERKRIAKYAGMYVMELLKNDIKPRDILTIDAFKNAIAVDMAMAGSTNTVLHLPAI
                     AYESGIELNLDFFDEISEKTPCLTKLSPSGKHHIEDLHMAGGIPAIMNELSKINGINL
                     DCKTVTGKTIRENIRNCEIENEEVIHTLKNPYSNQGGLAILKGNLALNGAVVKKSAVA
                     EEMLVHEGPARVFNSEEEAVNAIFGKKINKGDVIVIRYEGPKGGPGMKEMLSPTSAVA
                     GMGLDKHVALLTDGRFSGATRGASIGHISPEAMEGGLIGLVEEGDIISINIPDKKLEL
                     KVDEVEIENRKLKFKPLEPKIKHGYLSRYAKLVTSANTGAVLK"
     gene            2684..3313
                     /locus_tag="PC465_003710"
     CDS             2684..3313
                     /locus_tag="PC465_003710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2650975.1"
                     /translation="MNREEKSKNSKEKIIQSAFSLFSSKGYDSTSTQDIINLSGLSRG
                     AMYHHFKTKEDILRSVTKELYSQMNNFLEYLVADDTLTANEKIIELVVHSANDYTRRK
                     MVHCSWLEKIPFALIEEVRNLNNVVAPNIAKIIKQGVENKEFSCEYPEELAEMLVFSI
                     DILLDPVLFKREYSEVCNRLDFLLFMLKKMDIPLIDEYGIQKFKDLFKQ"
     gene            3339..4151
                     /locus_tag="PC465_003711"
     CDS             3339..4151
                     /locus_tag="PC465_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2650976.1"
                     /translation="MFYNAKSCQMMIGSNTVNYIEFGSGKKTLIILPGLGDGLFPLHG
                     KIQAIAFAFRYKQFAKDYKVYVFSRKNQITEKYSTRDMAKDQADIMKKLGIMKAEVMG
                     VSQGGMIAQYLAIDYPELVEKLVLAVTSSKQNDTIQNVICSWIDMAKKQNYNDLMIDT
                     AKKSYSERYLKKYQLFIPFLGKVGKPKDFKRFIIQATSCIEHNAFSELNKITCPTLII
                     GGANDKIVGNNASFHLAEKIKKSEIFIYEGLGHATYEEAQDFNERVLEFLNK"
BASE COUNT         1719 a          497 c          805 g         1414 t
ORIGIN      
        1 atggaaataa taatagtata ttttggtaaa gtaggaggaa ttttatgaaa tggattaaat
       61 ggtatagtat tacatgcata tgtattttta tagtagtagc tttttatatg tttatatttc
      121 ctaataaaat agaaactatt gatacttcat ctgcatatag ctttgttgaa aagaaagtac
      181 caaatagtgc tgtgtatcaa ggatacaaaa agaatccagt tgatggtact actacaattt
      241 attacagcta tgataattca actcatatag ttagattatc acatccagaa gactattcaa
      301 ggaagattaa ttgggataaa gtttcaaaca tcagatttga ttaatcttta atatttataa
      361 aagtctatat atctaaggca aatatattac taaggcaaat atattattaa tcttattcat
      421 agttgagcac tttctattat agaagtgctt cttctgattt atatcataaa atattactca
      481 acaatttgta aaatatatta gtttataaaa tatatttaaa agataatatt atataatacg
      541 attgtgtaag atattgataa aaaatcgtaa taaattttca ttagtatatg ctaatatttt
      601 tttacaattt tcgtaattaa ttaatagaaa aatatattat aataatatta tgaaaattta
      661 aaaaagtaag aaagaggtaa tattatgaga agtgatataa aaaaaggaat agaaggagct
      721 ccaaagagag cgttaatgta tggaatgggt cttactaaag aagaaattga aagaccatta
      781 ataggtatag taaatgcaca aaatgaggtg attcctggtc atctgcatct tgatgaaata
      841 gcagaagctg caaaaaatgg agtaagaatg agtggtggtt tgccattaga atttcctgct
      901 ataggggtat gtgatggtat agctatgggg catgtaggaa tgaattattc cctggcttca
      961 agagaattaa tagcagattc aatagaagct atggctatgg cacatggttt tgatgctttg
     1021 gtacttatac ctaattgtga caagatagtg ccaggtatgt taatggctgc tgcaagactt
     1081 aatataccaa gtattgttgt gagtggaggg cctatgcttc caggtaaaaa aaatggaaaa
     1141 gtatatgatt ttaactctgc aatggagggt gttggagcat gtaaagatgg aatagtaagt
     1201 gaagaagaat tagaagcgtt agccatgaac tcttgtcctg gatgtggttc atgttctggt
     1261 cttttcacag caaatagcat gaattgttta acagaagctt taggcatggg gataccatat
     1321 aatggtactg ctgcgtcaca ttctggagaa agaaaaagga tagcaaaata tgcaggtatg
     1381 tatgttatgg agttacttaa gaacgacata aaacctagag atattttaac aatagatgct
     1441 tttaaaaatg ctatagctgt ggatatggca atggctggtt ctacaaatac agtacttcac
     1501 ttacctgcaa tagcttatga atcaggaata gagcttaact tagatttttt tgatgaaata
     1561 agtgaaaaaa ctccttgttt aacaaaatta agtccaagtg gaaaacatca tattgaagat
     1621 ttacatatgg caggaggaat accagctata atgaacgagc tttcaaagat aaatggaata
     1681 aatttagatt gcaaaaccgt aacaggcaag actataaggg aaaatataag aaattgtgaa
     1741 atagaaaatg aagaagtaat acatacatta aagaatccat atagtaacca aggtgggctt
     1801 gcaatattga aaggaaatct tgctctaaat ggagctgttg taaaaaagtc agcagttgca
     1861 gaagaaatgt tagttcatga aggaccagca agagttttta attcagaaga agaagctgta
     1921 aatgctattt ttggtaaaaa aataaacaaa ggtgatgtta tagttataag atatgaaggt
     1981 ccaaagggtg gtccaggaat gaaagaaatg ctatctccta catcagcagt tgcaggaatg
     2041 ggacttgata agcatgtagc acttcttact gatggtcgtt tttcaggggc aactagagga
     2101 gcatctatag gccatatttc tccagaagct atggaaggtg gtttaatcgg actagttgaa
     2161 gaaggagata taatttctat aaacatacca gacaaaaaat tagagttaaa agtagatgaa
     2221 gttgaaatag aaaatagaaa attaaaattt aaacctttag aaccgaaaat aaagcatgga
     2281 tacttaagta gatatgctaa attggtaaca tcagcaaata caggagcagt tttaaaatag
     2341 tagactatat ttatgtaaat tagaaaaagt taagaaaata ttaattggat atcttaggtg
     2401 ttatatcact aatgaggtat cctttttatt ttgtatgaaa aacacagcaa aatcttgatt
     2461 atctttgaaa acaatacatc tctattataa ggaatacgag tacagcatag agatgtatct
     2521 tttagacctt gttgaggtaa tacaactttt taaaagtttg atgtggaatg cttttcattc
     2581 catctgaact atgaagaaat tgaaagtcag ttaattcttg acataataaa tattaaaatg
     2641 tataataaaa aacaaacaga cagtctgttt ttaggaggga aatatgaata gagaagaaaa
     2701 aagtaaaaat agtaaagaaa aaattatcca atcagcattt tcactatttt cgtctaaagg
     2761 atatgattca acatctacac aagatattat caatttatct ggtctatcta gaggtgcaat
     2821 gtatcatcac tttaaaacta aagaagatat actgagaagt gtcacaaaag aactttactc
     2881 acaaatgaat aattttttag agtatcttgt tgctgatgac acccttacag caaatgaaaa
     2941 aataatagaa ttggttgttc atagtgcgaa tgattacaca cgtagaaaaa tggtacattg
     3001 tagctggtta gaaaaaatcc cattcgcttt aatagaggaa gttcgtaatc tcaacaatgt
     3061 agttgcaccc aatattgcta agataattaa acaaggtgtt gaaaataaag aattttcttg
     3121 tgaatatcca gaggaattag ctgaaatgct cgtttttagt attgatattt tacttgaccc
     3181 tgtattattt aaacgtgaat acagtgaagt atgtaatagg ttggattttt tattattcat
     3241 gttaaaaaaa atggatattc ctctaattga tgagtacggt attcaaaaat ttaaagattt
     3301 atttaaacaa tgataatagg aaaagtgagg aatagactat gttttataat gcaaaaagct
     3361 gtcaaatgat gataggaagt aatacagtga attatattga atttggtagt ggtaagaaga
     3421 cactaattat tttaccagga ttaggagatg gtttatttcc tttacatgga aaaatacagg
     3481 cgattgcttt tgcttttaga tataagcaat ttgcaaaaga ttataaggtt tatgtattta
     3541 gtagaaaaaa tcaaattaca gaaaaatatt ccacaaggga tatggctaaa gaccaagcag
     3601 atataatgaa aaaacttgga attatgaaag cagaagtaat gggtgtttct caaggtggaa
     3661 tgatagctca atatctggca attgattatc ctgagttagt tgagaaactt gtgttggcag
     3721 ttacttcttc aaagcaaaat gatactatcc aaaatgttat ttgtagctgg attgatatgg
     3781 cgaagaagca gaattacaat gatttaatga ttgacacagc aaagaaatcc tattctgaaa
     3841 gatatttaaa aaaataccaa ttatttattc cttttttagg aaaagtaggt aaaccaaagg
     3901 attttaaacg atttattatt caagcgacct cttgcataga acataatgct ttttccgaat
     3961 taaataaaat aacatgtcca accttaatta taggaggtgc taatgataaa attgttggaa
     4021 ataatgcttc ttttcattta gcagaaaaaa ttaaaaaaag cgaaatattt atctatgagg
     4081 gattgggaca cgctacatat gaagaagcac aggattttaa tgaaagagtt ttagagtttt
     4141 taaataagta aacacctttg ttaaaaatat acatatgaag attggaaatt taatgttaaa
     4201 aatagaaaca tgaaaatatg cttaactggt atttttacta ttcataacca atttttgata
     4261 cattatctac tataaataca aatatagctt caatgtgatt atatattgtt gtattggtaa
     4321 agcacttata caaacagagg aattttgtaa attcatatta tacccacatt tgttaactta
     4381 tgaaaatata atcaaaattt ttatgagctt tttatataaa aaatataatg tttgt
//
LOCUS       DAMJXI010000147         4305 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.156, whole genome shotgun sequence.
ACCESSION   DAMJXI010000147 DAMJXI010000000
VERSION     DAMJXI010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4305
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.156"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(255..1298)
                     /locus_tag="PC465_003712"
     CDS             complement(255..1298)
                     /locus_tag="PC465_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HDF2650977.1"
                     /translation="MGTKIVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVA
                     ETGVHFLIPFLDKMAYVIDLREIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVF
                     EIANPIAAIENLTATTLRNIIGELDLDETLTSRDIINVKMRTILDEATDKWGIKVNRV
                     ELKNIMPPQDIQVAMEKQMRAERERREAILQAEGNKSAAILQAEGEKQSAILTAEAKK
                     EAMVRVAEGEKESAILVAEGEAEAIRQTAIAKAQGEAEMIKRTQMATAEGLKLVFSAM
                     KEADIDNNILALKSMEALEKMAEGKSTKLVLPSEAVNFLGTFKGIKEVMSDDNKEVLD
                     IKEVLNDNESLKK"
     gene            complement(1319..1765)
                     /locus_tag="PC465_003713"
     CDS             complement(1319..1765)
                     /locus_tag="PC465_003713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HDF2650978.1"
                     /translation="MKLIWLIVAVLFGIAEMLTPSLTLIWFSVGAVILIFLSSFIESI
                     FLQILIFAVISIAMLVVATKKIVKKDKGYKSNTNLQAMMSKKGIVTEEISPNNTGLVV
                     VEHETWTAISIDGEKIEKGSTVEVLKIEWVKLVVKKVDATVNVTNQ"
     gene            complement(1939..3519)
                     /locus_tag="PC465_003714"
     CDS             complement(1939..3519)
                     /locus_tag="PC465_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HDF2650979.1"
                     /translation="MLIGTSKLSRNVDTACVEEVGIPMIVLMENAVISAMKNMDIDMY
                     NSYTVVCGVGNNGGDGLGIARHLNTYGKEVNVFLVGNLEKLSECSKINYNVLLNMGIN
                     IININKNDLSEKNYGDENEVDKIIKVEKQNIIKNKNLTIFKDRVSKSDVVVDAIFGTG
                     LKRDITGIFKEVIDIVNDNSKNTYSIDIPSGIDSDNGNVLGTCIRANKTISFEFYKRG
                     FLNYDTSTLIGDVVVEKIGVPDFITRKYHDEEFITDKTFVKNNIRRRDKHGFKSDFGK
                     VSIVAGSKGFYGASFIATESAVKSGSGLVTLISSEDVQEKVSIRLTEAMTLNFEEERL
                     NKLLNSSDAIGFGPGMGDNSQTFDKLLKIVENSNCPIVLDADGLNVMKDRCYKFLEWK
                     NRFVITPHLGEMARLTGDSIGYIREHRVDVAKEFAQKYNLVVLLKGYQTVITDGKKTY
                     INPTGNSCMATGGMGDCLLGMITSFIGQGMDILEATVSGAYIHGYIGDKLSKAMYTVN
                     ATDLISNISLTMKELLDI"
BASE COUNT         1402 a          757 c          403 g         1743 t
ORIGIN      
        1 ataaatagac taactaaaac catgcttatt tgctatatgt tttatataat attatataac
       61 actttttaca ttagtaaagg ataaattgta taaagattct gttaatttat ttttataatt
      121 tcatctttct aataaaaaca aagaagaaga cttaaaaatt tataagtcct cttcttttca
      181 acgtgcattt ttgtgctata tttaattaat tcgaccttta atttccatat ccttcctatg
      241 ataacaaaac tcttttattt ttttaatgat tcattatcat ttaaaacttc ttttatatca
      301 agtacttctt tgttatcatc actcataact tcctttattc ctttgaatgt tcctaggaaa
      361 ttaactgctt ctgaaggtaa aaccagtttt gttgacttac cttcagccat tttttcaaga
      421 gcttccatag attttaatgc tagaatatta ttgtctatat cagcctcttt cattgctgaa
      481 aaaactaatt ttaaaccttc tgctgttgcc atttgagttc tttttatcat ttcagcttca
      541 ccttgtgcct tagcaatagc tgtctgtctt atagcttcag cttcaccttc tgccactaat
      601 atagcagatt ctttttcacc ttctgctaca cgtaccatag cttctttttt ggcttctgct
      661 gttaatatag cagattgttt ttcaccttca gcttgaagta ttgcagctga cttattacct
      721 tctgcttgaa gtattgcctc tcttctttct ctttctgctc tcatttgttt ttccattgca
      781 acttgaatat cctgaggagg cattatattt tttaactcta ctctatttac ttttataccc
      841 catttatctg ttgcttcatc aaggatagtt ctcattttta catttattat atctcttgat
      901 gttaatgttt catctaaatc aagttcacca attatatttc ttagtgttgt agctgttaaa
      961 ttttcaatag cagctattgg attagctatc tcaaacacat atctaactgg gtctgtaact
     1021 ttataatata caactgtatc aatctgcata gttacattat ctttagttat aactggttga
     1081 ggtggaaaat ctattacaat ttctctaagg tcaattacat atgccatttt atctaaaaat
     1141 ggtattaaga aatgtacacc tgtttcagct actttttgaa acttaccaag tctcattatt
     1201 atacctactt tagattgttt tataactctt atacaagtta aacttattgc tacgactact
     1261 actattaata caatacttaa aacaatttta gtacccatac tataaatcct cctttattct
     1321 attggtttgt cacattaact gtggcgtcta cttttttaac aactaatttt acccattcaa
     1381 tttttaatac ttctactgta gaaccttttt ctatcttttc accatctata gaaatagccg
     1441 tccatgtttc atgttcaact acaactagac ctgtgttatt tggagaaatc tcttctgtaa
     1501 caataccttt tttagacatc attgcttgta aattagtgtt agatttatag cctttatctt
     1561 tttttactat ttttttagta gctacgacta acattgctat agaaattact gcaaatatta
     1621 aaatttgtaa gaaaatactc tctataaagc tacttaaaaa tataagtatt acagctccta
     1681 cactaaacca tatcaatgtt aagcttggtg ttaacatttc tgctattcca aataagactg
     1741 ctactatcaa ccatattaac ttcatactat ctaccctctt ttcatatgaa ttataaaacc
     1801 ctatataaat tatatgttta tacaatgttt ttgaatataa atttaaatta caaaacaata
     1861 aaataaataa attaattaat agtattatat caacatactt tgttaaaatt gttacaaagt
     1921 agtatcaaat atcaccaatt atatatccaa caactctttc attgttaatg aaatgttact
     1981 tattaaatcc gtagcattta ccgtatacat tgctttgctc aatttatctc ctatatagcc
     2041 atgtatatat gctccactaa ctgtagcttc caatatatcc ataccttgac ctataaatga
     2101 agtaatcatt ccaagcaaac aatcacccat tccaccagtt gccatacagc tatttcctgt
     2161 aggatttata tatgtttttt taccatctgt tatgacagtt tgataacctt ttaaaagcac
     2221 caccagatta tatttttgag caaattcttt tgcaacatct actctatgtt ctcttatata
     2281 cccaattgaa tctcctgtca acctggccat ttctcccaaa tgaggtgtaa ttacaaatct
     2341 atttttccat tctaaaaact tataacatct gtccttcata acgttcaatc catctgcatc
     2401 taatactatt gggcaattag aattttctac tatcttaagt aatttatcaa atgtttgact
     2461 attatctccc atacctggac caaaaccaat tgcatcacta gaattaagta atttatttaa
     2521 tctttcttct tcaaaattta aagtcattgc ttctgtaagt ctaatagata ccttttcttg
     2581 cacatcttca ctactaatta atgttacaag tccactccca ctcttaacag cagattcagt
     2641 tgctatgaaa cttgcaccat aaaatccttt tgaacctgca actatagata cttttccaaa
     2701 atcactttta aaaccatgct tatctcttct tctaatatta ttttttacaa aagtcttatc
     2761 agttatgaac tcttcatcat ggtattttct tgtaataaaa tctggaacac ctatcttttc
     2821 tacaactaca tcacctataa gtgtgctagt gtcatagttt agaaaacctc ttttataaaa
     2881 ctcaaagcta atcgttttgt ttgctctaat acaagttcct aatacatttc cattatcgct
     2941 atctatacct gaaggaatat ctatagaata tgtattttta ctattatcgt ttactatgtc
     3001 aataacttct ttaaaaatac cagttatatc acgttttaat ccagtcccaa atatagcatc
     3061 tactacaaca tcacttttag atactctatc tttaaaaatt gttaaatttt tattttttat
     3121 aatattttgt ttctcaactt taataatttt atctacttca ttttcatctc cataattttt
     3181 ttcacttaaa tcatttttat taatatttat aatattaatt cccatattta aaagtacatt
     3241 gtaatttatt ttagagcatt cacttagttt ttcaagatta cctactaaaa atacgtttac
     3301 ttcttttcca tatgtattta gatgtcttgc tattccaaga ccatctcctc cattatttcc
     3361 aacaccacat acaactgtgt aactattata catgtctata tccatatttt tcattgcaga
     3421 tataaccgca ttttccatca atacaatcat tggaatccct acttcttcta cacatgcagt
     3481 atcaacattt ctgcttaatt tagatgtacc tattagcata aattatcact cctataaagt
     3541 taaagacttc ttaaatactt accaaaaata tctattgaaa tctttttaat cccataaata
     3601 tcataaataa aatcactaaa actaagagtt ttgaaataat ttaaaataac aaaaaatttt
     3661 gaattaaaac aattatttaa tttattatac catataattt aagttattat gttgatttaa
     3721 aacctattta cactaattat ctaaatatct ctttattttt ataatctttt atgacttatt
     3781 tatatttttc atttttataa aaaaacaata attaagaata taactatatt ctacatgtaa
     3841 aaattttttt atttaaactc aattttctga taatttgata atttttcaaa atttatagtt
     3901 gacttttatt ttttactgta ttaaactaat tactatacaa aacagaaaac aaaattttca
     3961 aaattattaa attaaaagga gaggtaaata tgaagacttt attaaacaaa caagtacgat
     4021 tttttagtag ccaatttagt tagggtttgt acctaagtta agacaaattg tcataacata
     4081 gatacaagcc ccttaggatt atgattttta aggattgtat ctatgttggc tatagtaatt
     4141 gttgttaaag tttttatttt atcatcataa tatagagcca catggattat actgtgtggc
     4201 ttattcgaat ttttgccata cagttatata tactgtgtgg tttttttata tcaaaatcat
     4261 tttttaaaac caaatttaaa aaaccattta aaatattttc aaagg
//
LOCUS       DAMJXI010000148         4155 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.157, whole genome shotgun sequence.
ACCESSION   DAMJXI010000148 DAMJXI010000000
VERSION     DAMJXI010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4155
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.157"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(261..1121)
                     /locus_tag="PC465_003715"
     CDS             complement(261..1121)
                     /locus_tag="PC465_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2650980.1"
                     /translation="MLLKKDRITFSEILILIVGCILMAISLNLFFNPHAIAAGGITGL
                     GVVLNSLFGVELWIVNLLLNVPLFIFAYKILSKKDCFKTVLGIIFLTIALKLTANMAT
                     LDITNDMYLAIISGSILMGVGQGLIFRINGSTGGTDLMALLLNKYFPTFSIPVLMGIV
                     DCVVVVLSGIVNRQVEIALYSTVALYILVKVSDLLIEGFNYSKSFTIISDLSKDISKK
                     IMEDLDRGATILKGEGAYTGENKNVLLVVVEKKEVVELKKLVKNVDPNAFIIITDIHE
                     ALGNGFKKIE"
     gene            1270..2160
                     /locus_tag="PC465_003716"
     CDS             1270..2160
                     /locus_tag="PC465_003716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2650981.1"
                     /translation="MAKLTLEHIKGNTYYIPLPTIVGVYVDGKDAILIDSGNNKDTAR
                     QVLRLLEEHNLIPKLIINTHSNADHIGGNAYLKNQTKCKIATTKIEGYFTENPILESA
                     FLYGGYPSKALKNKFLLAKESEVDYIIPPNGKIVDTELEAISLPGHYFEMIGVRTPDN
                     VLFVADSLTPENIITKYHFFFLLDIDSQFKTLEKLRMLEADFFVPSHSVKTTDIKSLI
                     NINKKKMEEIIDNIKKVCYEPVMIDEVIEKMCDLYNVKLDANQYVLVGSTIRSYITYL
                     YENNMVEYIFDGGKMMIKAV"
     gene            2378..4132
                     /locus_tag="PC465_003717"
     CDS             2378..4132
                     /locus_tag="PC465_003717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp23"
                     /protein_id="HDF2650982.1"
                     /translation="MYIMNKKFKKFSKKLSILILVLTMFLFNNLTANAQIKEDSIIGI
                     DRYETAGLIADRQTYDTVILVNGDKNLSDGLSSSGLAGAINAPILLTKKSEIPKATLN
                     RLDNKSLNVVKKVYIIGGYNTIENSVEKDIKRKGIQVERINGNNRIETSYNVAKKINE
                     VSSVKEVMLTNGFVGEADAMSIAPVVAKNKGAIILTDGKSVPFKTEGLNVYAIGGKSA
                     INEDLVNETKAIRIGGNDRFETNKKVMEKFYNGATDFYITNGYQLVDALTLSPLAKEK
                     PIVLVADGSNKGILKGAKSITKVGGIDANIYKQCLDMIKYNNMDMTPNILKHLTSVEG
                     NEVSEILIESDNLGVVVEKTNTNKFEFDYVSVTNEKNCTFSVYKENSSNNIKNGKLVV
                     SAKKKIDKKDSDLQDMNGDNMINANKDRMVNVIKIGVPDKMYSNFKVDVESGSVELYN
                     IKGGATVDVNDGIANIVDNNVTNPFNINTNSGISGVTAETISSEIKFRANNGIVNVTA
                     TNINGNISLFGSDNKGTFDGIFKLNLKKEPSNLHLKLIGNGINKLPEGWSKNYILGNG
                     QPIIEVKNNGINNISIGE"
BASE COUNT         1696 a          437 c          646 g         1376 t
ORIGIN      
        1 tttgtagttt tataatattt aaatttgtat ttgattgtta taaagtaaag taagtaataa
       61 agttagactc aataattcta aaatttctaa gcatactatc taaatgagaa cggatttgga
      121 aatacttgta taaaacaata attgatacat ttaattttta tcttaaaaac aacaattata
      181 atatataaat agcaagtata atataacata taaaaagttg aatttgtata tgttaattat
      241 acttgctatt tatttgttag ttattctatt tttttaaatc cattacctaa agcttcatgt
      301 atatctgtaa ttataataaa agcattaggg tcgacatttt ttactaattt tttcaattcg
      361 acaacttctt tcttttcaac tactactaaa agtacatttt tattttctcc agtatatgca
      421 ccttctcctt ttagaatagt tgcacctcta tctaaatctt ccattatttt tttacttata
      481 tcttttgaaa ggtcagatat aatagtgaat gatttggaat aattaaatcc ttcaataagc
      541 aagtcactaa cttttactaa aatgtataaa gccacagttg aataaagtgc aatttcaacc
      601 tgtctattta ctatacctga taaaacaact acaacgcagt ctacaatacc cattaaaaca
      661 ggtatactaa atgtaggaaa atatttattt agtaggagtg ccattaaatc agttccacct
      721 gtagagccat ttattctaaa aataagtcct tgaccaactc ccattaaaat agaaccagat
      781 ataattgcaa gatacatatc atttgttata tctaatgtag ccatatttgc agtaagctta
      841 agtgctatgg taagaaaaat tattcctaaa accgttttaa aacaatcttt ttttgaaagt
      901 attttgtaag caaatatgaa taatggaaca tttaaaagta aattgacaat ccaaagttct
      961 acaccgaata atgaatttaa aacaactcca agtcctgtta taccaccagc agcgattgca
     1021 tgtggattaa aaaataagtt aagagaaatg gccattaata tacagcctac aattaatatt
     1081 aaaatttctg aaaaagttat tctatctttt ttcaataaca tcactcctta tatatagatt
     1141 ataatatata ttatatagtt tttccaattt ttaataaaag aaataaaaat atattataaa
     1201 aacaatttga ttggaatttt cagaaaatta atgctataat taaaagtaaa tttaaaggga
     1261 ggttataaaa tggctaaatt aactctagaa catataaaag gaaatacata ttatattcca
     1321 ctccctacaa tagtaggtgt atacgtagat ggtaaagatg caattttaat tgacagtgga
     1381 aataataagg atacagctag acaagtttta agattattag aagaacataa tttaattcct
     1441 aaattaataa taaacactca ttcaaatgca gaccatatag gaggaaatgc atatttgaag
     1501 aatcaaacaa aatgcaagat tgctacgact aaaattgaag gatattttac agaaaatcca
     1561 atattagaat cagcattttt atatggtggc tatccaagta aagcactgaa gaataaattt
     1621 ttattagcaa aggaaagtga agttgattat attatacctc caaatggcaa aattgtagat
     1681 acagaacttg aagcgatttc tcttccaggt cattattttg aaatgattgg tgttagaact
     1741 ccagataatg ttttgtttgt tgcagatagt cttacaccag agaatataat tactaaatat
     1801 cattttttct tcctactgga tatagattca cagtttaaga cactagaaaa attgagaatg
     1861 ttagaggctg atttctttgt tccaagtcac tctgtcaaaa ctacagatat aaaaagtttg
     1921 attaatatta ataagaagaa gatggaagaa ataatagata atattaaaaa ggtttgttat
     1981 gagccagtta tgattgatga agttattgaa aaaatgtgtg atttgtacaa tgtcaagctt
     2041 gatgctaatc aatatgtgtt ggttggaagt acaatacgtt cttatataac ttatttatat
     2101 gagaataata tggttgaata tatatttgat ggtggtaaga tgatgataaa agctgtgtaa
     2161 atagtaataa ttttcaaatt atatgatgaa attgttttag tatgactgtt atttgaaaag
     2221 taatataaaa aaatttatat aaataagcta agatgattga tataaagtta ctgataattt
     2281 taaggtaata tatacgttac tataatatta tgttattatt tgtaaataag gggataattt
     2341 ataagcaaat taaagacctt aatttacagg aggaatagtg tatattatga ataaaaaatt
     2401 caaaaaattc agtaaaaaac taagtatatt aattttagtt ttgactatgt ttctttttaa
     2461 taatttaact gcaaatgcac agattaaaga agattcaata ataggaattg atagatatga
     2521 aacagcagga cttatagcag atagacaaac ttatgatact gtaatattag ttaatggaga
     2581 taaaaattta tctgatgggc tttcatcaag tggattagct ggagctatta acgcaccaat
     2641 acttttgact aaaaaaagtg aaataccaaa agctacttta aatagactag ataataagag
     2701 tttaaatgtt gtaaaaaaag tatatataat tggtggttat aatactattg aaaattcagt
     2761 agaaaaagat ataaaaagaa aaggtattca agtggaaaga ataaatggta acaatagaat
     2821 tgaaactagt tataatgtag ctaaaaaaat aaatgaagta agtagtgtaa aagaggtaat
     2881 gcttacaaat ggatttgtag gagaggctga tgctatgagt atagcacctg tagttgcaaa
     2941 aaataaagga gctataatac ttacagatgg gaaatcagtt ccatttaaga ctgaaggttt
     3001 aaatgtttac gctataggtg gcaaatctgc gataaatgag gatttagtaa atgaaactaa
     3061 agcaattaga atcggaggaa atgatagatt tgagaccaat aaaaaggtaa tggaaaagtt
     3121 ttataatgga gctacagatt tttatataac aaatggatat caattagtag atgcactaac
     3181 attatctcct ttagccaaag aaaaaccaat cgttttagtt gctgatggaa gtaataaagg
     3241 tattttaaaa ggagctaaaa gtataacaaa agttggaggt attgatgcca atatatataa
     3301 acagtgttta gatatgatta aatataataa tatggatatg actccaaata ttttaaaaca
     3361 cttaacttca gttgaaggaa atgaagtttc tgaaatactt atagaatcag ataatttagg
     3421 tgtggttgtt gaaaagacga ataccaataa atttgagttt gattacgtaa gtgtaactaa
     3481 tgaaaaaaat tgtacttttt ctgtatataa agaaaattct tctaataata taaaaaatgg
     3541 aaagctagtt gtaagtgcta agaaaaaaat agataagaaa gatagtgatt tgcaagatat
     3601 gaatggcgac aatatgataa atgcaaataa agataggatg gtaaatgtga taaaaattgg
     3661 agttcccgat aaaatgtatt ctaattttaa agtagatgtt gaaagtggtt cagtagaact
     3721 ttataatatt aaaggaggag ctactgttga tgtcaatgac gggattgcta acattgttga
     3781 taacaatgta acaaatcctt tcaatataaa tactaatagt gggatttcag gtgtaacagc
     3841 tgaaactata tcatctgaaa taaaatttag agcaaacaat ggaattgtaa atgtaacagc
     3901 tacgaatata aatggcaata taagtttatt tggaagcgat aataaaggta cctttgatgg
     3961 aatatttaaa ttaaatctga aaaaagaacc atcaaattta cacttgaagt taattggaaa
     4021 tgggataaat aaattgccag aaggttggtc taaaaattat attttaggaa atggacaacc
     4081 aattattgaa gttaaaaata atggcataaa taatatatca attggagaat aaaaacatat
     4141 gaaaataaag tttat
//
LOCUS       DAMJXI010000149         4134 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.158, whole genome shotgun sequence.
ACCESSION   DAMJXI010000149 DAMJXI010000000
VERSION     DAMJXI010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4134
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.158"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            169..1572
                     /locus_tag="PC465_003718"
     CDS             169..1572
                     /locus_tag="PC465_003718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2650983.1"
                     /translation="MEKKKIGLWSLVFMNVSALYGIRWIAKSTASSFGLGLGAIPMWL
                     LFSFIYFVPGALICAELASTYQKGDGGLYDWVKEAFGEKYGFLVSWLNWTAKIFWYSS
                     FLTFLAVNVSYTIGNPALADNKMFVLILSLIIFWALSLIATKGISFTKIFTNTGALGS
                     TIPSAILIIFSFVAVFVLKKHDIASTYTIASMTPKLNMDAFVAISAIMFGLAGAETAA
                     NFITEIDKPEKNFPKAILISAGIVASLYVLGSIAITMIIPPDQITASKGVLDALSAVC
                     ASLGIGSWLVQLIAFGIAFSVLGAIVLYIASPIKMLFGSVKKGIFPDSLVEVNEHKIP
                     SKAVILQAIIVTIILLVTTLMPSVDAIYNVLVTMTALTALFPYVLLYASYIKLRKERP
                     DEIRPYTMAKSTSTCLGLAKMVLVVTVVGILLSAAPVMPTFAENVIYEIEMIGGGLLV
                     ILSGLWLWNRYEKKTAK"
     misc_binding    1663..1903
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1946..2644
                     /locus_tag="PC465_003719"
     CDS             1946..2644
                     /locus_tag="PC465_003719"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HDF2650984.1"
                     /translation="MNVIGIIGAMDEEVSILVDLMDIRETIKKASLEFYKGILEGKNV
                     VLVKCGIGKVNSALCAQILISEFKVDAIVNTGVAGALNEKLDVNDIVISTDAIQYDVD
                     TTAFGDPKGVIPRMKTSVFKADERLIDAAYKSSVEEVKTHKVLKGRVVTGDKFINSKE
                     LKEELVNDFGGYCGEMEGGAIAHVCYLNNTPFVIIRAMSDKADGSADVTYDVFVHDAA
                     NNSKDIVLNMLKSI"
     gene            2667..3668
                     /gene="trpS"
                     /locus_tag="PC465_003720"
     CDS             2667..3668
                     /gene="trpS"
                     /locus_tag="PC465_003720"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HDF2650985.1"
                     /translation="MSEKKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVD
                     LHAITVPQDPKVLRANTIELLAQYIACGLDPEKNTIFIQSHVKEHVELMWVLNTMTYM
                     GELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD
                     LANRFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIK
                     RKIKRSVTDSLGVVKYNDEQPGIKNLIDIYSNLSKKSVEEIVNMYEGKGYGIFKEDVA
                     EVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKTLRKVYKKVGFIERRY"
BASE COUNT         1557 a          458 c          734 g         1385 t
ORIGIN      
        1 ttatcatttt taataagatt tgatttcaaa gtatttaagg tttattatta aaactgtttt
       61 tgaatatgca aatattttga aaaatatcag tttaataata atgaatctat tttattaatt
      121 ttgaaattaa atttaaaata attaatagag aggggaaatt aaattaggat ggaaaagaaa
      181 aaaataggcc tatggagttt ggtatttatg aatgtatcag ctttatatgg tataagatgg
      241 atagctaaat ctacagcatc aagctttggt ttaggattag gtgcaatacc tatgtggtta
      301 ttattctcat ttatatactt tgtaccagga gctttaattt gtgctgaatt agcttctaca
      361 tatcaaaaag gtgatggagg tctttacgat tgggttaagg aagcctttgg agaaaagtat
      421 ggatttttag tttcttggtt aaactggaca gctaaaatat tttggtattc ttcattttta
      481 actttcttag cagtaaatgt ttcttataca ataggaaatc cagcccttgc tgataataag
      541 atgtttgtac ttatattatc tttaataata ttctgggcat tatctcttat agcaactaaa
      601 ggaataagtt ttacaaaaat atttactaat acaggtgcat taggttcaac aataccaagt
      661 gctatactta taatattttc atttgtagca gtatttgtgt tgaaaaaaca tgatatagct
      721 tctacataca caatagcttc aatgactcca aaacttaata tggatgcatt tgttgctata
      781 tcagctataa tgtttggttt agcaggagca gagactgctg ctaacttcat aacagaaata
      841 gataagcctg aaaagaactt ccctaaggca atattaatat cagctggaat agtagcttca
      901 ttatatgtat taggttcaat tgcaataaca atgataatac caccagacca aattactgct
      961 tctaaaggtg tattagatgc actttctgct gtttgtgcgt ctttaggaat tggttcttgg
     1021 ttggttcaat taatagcttt tggtatagct ttttcagtat taggagcaat agttctttac
     1081 atagcatcac caataaaaat gttatttggt agtgttaaaa aaggaatatt tccagatagt
     1141 ttagtagagg taaatgaaca caagatacct tctaaagcag ttatacttca agcaataata
     1201 gttactataa tactattggt gactacatta atgccttctg ttgatgctat atacaatgtt
     1261 cttgtaacta tgacagcatt aactgcatta ttcccatatg tattgttata tgcttcttat
     1321 attaaactaa gaaaagagag accagatgaa attagacctt atactatggc aaaatcaaca
     1381 agtacttgcc taggtttagc aaaaatggtt ttagttgtaa ctgtagtggg tatattatta
     1441 tctgcagcac cagttatgcc tacatttgct gaaaatgtta tatatgagat agagatgatt
     1501 ggtggaggtc ttctagttat attatctggt ctatggttat ggaatagata tgaaaagaaa
     1561 acagctaaat aaaatgtatt ttaaaaattt cttttggata ttataatata tagttgacaa
     1621 tttatagtgt aaggaatatt ataaaataaa gaaattaata aattaaatcc tgagataaga
     1681 aatagtaaat aaatatattt ttgcacagag aattaaggat gctgagaact taataaaaag
     1741 tatttattga atgggtcttt gaggagtaaa atgaaatgta atttaagatt acagagtatt
     1801 tgatatcgtg tatgcacgtt atagcatata ttaagatata tatattcaat tttgagtgta
     1861 tataaattta ggtggtacca cggaaaatat atccgtccta ttgatttagg acggattttt
     1921 taatatagaa aatttaggag gaaaaatgaa cgtaatagga attataggtg caatggatga
     1981 agaagttagt attttagttg atttaatgga tattagagag actataaaaa aagctagctt
     2041 agaattttat aagggaattt tggaaggtaa gaatgtagta ttagtaaagt gtggcatagg
     2101 taaggttaac tctgctcttt gtgcccagat actaataagc gaatttaagg ttgatgctat
     2161 tgttaataca ggtgttgcag gagctttaaa cgaaaaactt gatgttaatg atatagtaat
     2221 atcaactgat gctatacagt atgatgtaga cactacagca tttggagacc ctaagggagt
     2281 tataccaaga atgaagactt ctgtatttaa agcagatgaa agacttatag atgctgctta
     2341 caaatcttct gtggaagaag taaagactca taaagtatta aaaggaagag tagttacagg
     2401 agataaattt ataaattcta aagaattaaa agaagaatta gtaaatgatt ttggtggata
     2461 ttgtggagaa atggaaggtg gagctatagc tcatgtatgc tatttaaata atactccatt
     2521 tgtaataata agagcaatgt ctgataaggc agatggaagt gctgatgtta cttatgatgt
     2581 atttgtacat gatgctgcca ataactctaa agacatagtt ttaaatatgt taaaatcaat
     2641 ataaatatat aaggaggtac aaaaaaatga gtgaaaaaaa agttatattt agtggagcac
     2701 agccatcagg caaaatgact ttaggaaatt atttaggagc tataaaaaac tggactgaac
     2761 ttcaagacaa ttatgattgt tattatagta tagttgattt acatgcaata acagtacctc
     2821 aagaccctaa agttttaaga gccaatacta tagaattact tgctcaatat atagcttgtg
     2881 gattagaccc agaaaaaaat actatattta tacaatcaca tgtcaaagag catgttgaac
     2941 ttatgtgggt attgaatact atgacttata tgggtgaatt aagtagaatg actcaattca
     3001 aagataaatc acaaaagagt gaagcaaatc taaatgcagg tttattcaca tatccagttc
     3061 ttatggctgc tgacatattg ttgtatcaaa ctgacctagt tccagttgga gatgaccaaa
     3121 aacaacattt agaattagct cgtgatttag caaatagatt taataataga ttttcaccta
     3181 cttttgtagt tccagaagga tactacccaa aaggtggagc aagagtgatg agtttgcaag
     3241 agccaactaa aaaaatgagt aaatccgatt caaatgaaaa tgcatttata ctattagcag
     3301 atgattcaga ttctataaag agaaagataa aaagaagtgt tactgattct ttaggtgttg
     3361 taaaatacaa tgatgaacaa ccaggtatta aaaatctaat tgatatatat tctaatttaa
     3421 gtaaaaagag tgtagaagag attgtaaaca tgtatgaagg aaagggttat ggcatattta
     3481 aagaagatgt ggctgaagta gtatcagaag ctttaagacc tataagagaa aaatatgttg
     3541 accttcttaa taataaagat tatttagaaa aaatatatag tatgggagca gaaaaagccg
     3601 aaaaacaagc tagaaaaact cttagaaaag tttataaaaa agttggattt atagagagaa
     3661 gatactaatt attagctatc tttacttgat aaataaattt taaagttatt aaaaaggtat
     3721 atgatatgaa agagagagtc tcaaagtgaa cttttgttca tgaggcactc ttttttgtat
     3781 gaaataaaat atattttaat catttcaaca atgaaaaaga ggattatctc tattttgaga
     3841 cagcatcttt tgataataaa aaaagatgag cttttgctca tctcaaaggg gttagattat
     3901 tcttactttg gggaaagtag aataaaggta aaagttaact gatgtcaact ttgtcttttt
     3961 tgcatatcac tactgagcat aaaaaaatca gaaaaccata gccttctgaa acaacttcta
     4021 acatacattg tattttatac ccaatatgta atttatgagt taattttaac tcttataatg
     4081 aaaattgtca ataatatatc aaaaaaatat tttttaaatt tatataatta aatg
//
LOCUS       DAMJXI010000150         3990 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.159, whole genome shotgun sequence.
ACCESSION   DAMJXI010000150 DAMJXI010000000
VERSION     DAMJXI010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3990
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.159"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(216..599)
                     /locus_tag="PC465_003721"
                     /pseudo
     CDS             complement(216..599)
                     /locus_tag="PC465_003721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     regulatory      840..937
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            992..1168
                     /locus_tag="PC465_003722"
     CDS             992..1168
                     /locus_tag="PC465_003722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650986.1"
                     /translation="MFGNKMDKCTHVLTAYISSSYDYCNFLDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            1394..1594
                     /locus_tag="PC465_003723"
     CDS             1394..1594
                     /locus_tag="PC465_003723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF2650987.1"
                     /translation="MNNGIVKWFNNEKGFGFISMEGRDDVFAHFSAIQTSGFKSLEEG
                     QQVSFDIVKGARGPQAENITIL"
     gene            2465..3310
                     /locus_tag="PC465_003724"
     CDS             2465..3310
                     /locus_tag="PC465_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2650988.1"
                     /translation="MNIIKSITLLLTLLIVILMTGCSPRESASEVAKKYIDKMNSGDY
                     ETAYSLLSKDSKKKISIENLEEFQNILVSTKRIISYKIGKEKIIKKYKHDGKEYKNVV
                     KLEETFNIKNLLYKKDDSLKVNRYFVVENNKYKLLLYESFKKEFGINSMDLAQLKLND
                     FGLKYFKEVDLILKKAIAINPTDSKLYYAQACNYMNFDGFPGYSDTTYNALDSINKSL
                     KYLDKNDSDYKKNASNIYNLKGVILMFHKRFDEAQQYLNKALYFNKDNEDPKYNLNTI
                     KKHLN"
     gene            complement(3534..3698)
                     /locus_tag="PC465_003725"
     CDS             complement(3534..3698)
                     /locus_tag="PC465_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2650989.1"
                     /translation="MFGKPKESVRFLDFNDVAEKFGEKKAVAIFDAIAGKKSKEHIIK
                     DIEKLVKNEV"
BASE COUNT         1510 a          493 c          456 g         1531 t
ORIGIN      
        1 agacagtaat ttatctatag tgttacttat attttatata tatggctatt tttcaacatt
       61 ttacaatata tataacattt atttttttaa cttttgtcag taaaatgtca gcaaaacact
      121 ttatccacaa tttttatata agttttccac aacttatcac caatattatc cacataaaaa
      181 aggtagcact tatattatta gctacctttt atttattaat ctttatattt ccagcttttt
      241 atccaacttc ctatttctat tattttttct tcagttattt cttctccatc atgtaatttt
      301 gaaattaatt ctgataaagg attgttatgt aaacctctaa aaactctttt tccctctatt
      361 ttgagatatt ctctctcttt tattaatact gtatagtgta catgcctccc aattctctat
      421 gatattaaaa aacctttttt ggttaatcta gctaaaagta taattgtagt tgtatgcttc
      481 caaccatatg ttttttctat ttcatctgca acatcttttg atattacagt tttataacca
      541 gtattccata tgcatttcat aatttttaat tctgtatctg gtaatttttt atttagcata
      601 atatattcct tctttcaatt tatgtcactt cttcttatgt cacttcttca aatttatcta
      661 gcttaaatta taataggagc tttttagaac aaaaactata tttaattttt accaggtact
      721 ctacgtgttt agtctgtttt taagtgtaaa ataatgttca tatctataaa tttatttaac
      781 tttcaaacaa tcctgttgaa taataactaa ttctattgta ttattttagt tgtagaataa
      841 aactaaatcg gcaaaactag agaaatttag tgacgcaaag ctatagggac taagacttat
      901 ataaatatct tatgagttat gtcagccagt tgccaaagag atagtgttct ttttgttttt
      961 atgaaagttt tttaggggga taataattta tatgtttgga aataaaatgg ataaatgtac
     1021 acatgtattg actgcttata ttagcagttc gtatgattat tgtaattttt tagatacaca
     1081 gttagatgat tttatattag agtacggaga aaatgtagta gagtcttgtt tacaccaagt
     1141 aatggtattg gtaagtaagt ataattagat agacattgat ttctagaaaa ccctttttag
     1201 ttttatctac atttatatta atatatagca atgtaaaacg tttaaatata tttttaatat
     1261 taagaataat taaaatgtta actaaaaaat ataattaagt agacatttct attaatctat
     1321 gatacaatag tatttgtggt aatacacaat taaatcaagt atatcttgat ataggttaat
     1381 aggagtattt ttaatgaata atggaatagt gaaatggttt aataatgaaa aaggattcgg
     1441 ttttatatca atggaaggta gagatgatgt gtttgctcat ttctcagcta tacaaacttc
     1501 aggatttaaa tcattagaag aaggtcaaca agtaagcttt gatatagtta aaggtgctag
     1561 aggtcctcaa gcagaaaata taactatatt ataatatata gatttttcgg gaaagactct
     1621 ttttagagtc tttttttatt gttaatatat gtaagataat cattggtgaa gtaaataagg
     1681 tatattgagt aatgttcttg atagtttata tgctaatgaa tttcaaaaaa ataagcactc
     1741 ctataaaaag agtgctctta atgtaaatat aaaccttcat tggtccagcc taataccccg
     1801 tattctccaa gttctaacta ttttttatat acattatcac tttcatccat atctaacaca
     1861 attatttctt ctttagaatc aatttgtaaa atatgaggac tgtgtgttgt gacaattatt
     1921 tgtgttttta ggagaattgt ttttaatgta ataaaaattt tacataccac atagttgata
     1981 taaaacccaa aataaactta gcatctccaa tgtttacaca tatacaatgc tcttaaaatt
     2041 gcagtgaacg cgcaatagtg caattgataa tacttatcat atattctcaa taccttatat
     2101 ttcaactgct aaacctcaat ttatcacaaa tatcgctcac tgcaaaattt ctatattttt
     2161 attatatcat agcatataat taatattttc aattaatttt tacatttaat tatgtttaaa
     2221 ttctataata atgcaacttt aatgtttctt tctggaacta atataaaaac tatttcagaa
     2281 agattaggtc atgcagatat aaaaataact atgaatagct actctcagtt tttagaagag
     2341 atggacagag aagcatttga aaatttgagc aaaatactat ttattatatt ttaaagaaga
     2401 tgacttattc aatatttgat gctagaatat aattaataaa aatttaatta taggtgattg
     2461 tattatgaat attattaaaa gcataacttt actcttaaca ttattaattg tgatattaat
     2521 gacaggctgt tccccaagag aaagtgctag tgaagttgca aaaaaatata ttgataagat
     2581 gaactctggt gactatgaaa cagcatatag tttattaagt aaagatagta aaaaaaaaat
     2641 tagtatagaa aatcttgaag aatttcaaaa tattttagtt agtacaaaaa gaataattag
     2701 ttataaaata ggtaaagaaa aaatcataaa aaaatataaa catgatggaa aagaatataa
     2761 aaatgttgtt aaattagaag aaacttttaa tataaaaaac cttctttata aaaaagatga
     2821 ttctctaaaa gtaaatagat attttgtagt tgaaaataac aaatacaagc tattattgta
     2881 tgaaagtttc aaaaaagaat ttggtattaa tagtatggac cttgctcaac ttaagcttaa
     2941 tgattttgga ctaaaatact ttaaagaagt tgaccttata ctaaaaaaag ctattgctat
     3001 taatcctact gattcaaagc tttattatgc ccaagcatgt aattatatga attttgatgg
     3061 atttcctggt tattcagata caacatataa tgctttagat tcaattaata aatctttaaa
     3121 gtatttagat aaaaatgatt ctgactacaa aaaaaatgca agtaatatat ataacttaaa
     3181 aggagttatt cttatgtttc acaaaagatt tgatgaagca caacaatatt taaataaagc
     3241 cttatacttt aacaaagata atgaagaccc aaaatataat ctaaatacaa taaaaaaaca
     3301 tctaaactag atatttaatt tttgaattta taaaatattt ttttatgtat aattcagcac
     3361 tgaatcataa tctctactaa actaattaca agtttaaatt ataaagactt atttctatat
     3421 aaatattact ctataacaat aagtttctta tttaaatttt aaaatattat ctaaaaatca
     3481 taaaaaagaa ggtataaaga gctaccctca agctcaatat accttataaa tatctaaact
     3541 tcatttttta ctaatttttc tatatctttg ataatatgtt ctttagattt ttttccagct
     3601 atggcatcaa aaattgcaac agcctttttc tctccaaact tttctgctac atcattaaag
     3661 tctaaaaatc taacactttc ttttggttta ccaaacatat aacacctctc atacattttt
     3721 atatatttat tataacttct atagacttat ttttcaccaa taaacgttag acaaattagt
     3781 ccctttattt ttttaaacta gctttacctt caaaattctt aacaaaaaca gtttattcta
     3841 ctctataaat aaaaatagac aatttaattt gtaggaaact gataatagaa tacagtaaat
     3901 aaaactttgt ttaatctatc tgaaaaagtt atctattaaa actgctatga atttataaag
     3961 aatattctag ttcataaaaa tacaaatatg
//
LOCUS       DAMJXI010000151         3985 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.160, whole genome shotgun sequence.
ACCESSION   DAMJXI010000151 DAMJXI010000000
VERSION     DAMJXI010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3985
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.160"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(226..1476)
                     /locus_tag="PC465_003726"
     CDS             complement(226..1476)
                     /locus_tag="PC465_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 domain-containing protein"
                     /protein_id="HDF2650990.1"
                     /translation="MATIKPFKAIRPNKYIVDKVAALPYDVMNSKEARRIAEGNPYSF
                     LHIDKSEIDLDENIDLYDEKVYLKARENLDEFRKQEILVKDDKECIYIYKQIMDGRAQ
                     VGIVACISVDESLNGTIKKHEYTRPEKEIDRTKHIKYCDANTGTILVTYKHQRMIDDI
                     INDFMDNNEPLYDFITDDKIEHTVWKIDNDDIIDNLVDKFEKLDYLYIADGHHRTASA
                     ENVAKEMRAKNPNYTGKEEFNYFIAMIAPDENLMVLDYNRVIKDLNGLSEEEFINKIK
                     ENFELEEIEGKEKYKPDKKGTFGMYLGDKWYKMKANKNLLEIEDPVDSLDISILQDYV
                     IDAILGIDNPRVDKRIDFIGGIRGLEELEKRVNEDMKVAFAMYPTSIEDLIRVADANK
                     IMPAKSTWFEPKVRCGLFLHEINE"
     gene            complement(1508..2449)
                     /locus_tag="PC465_003727"
     CDS             complement(1508..2449)
                     /locus_tag="PC465_003727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HDF2650991.1"
                     /translation="MYNILVTDGIEKEAARKLRELDFNVIEQFYEKDVLGDKLKDVDV
                     LVVRSATKVTKDVIDKALEGKKLKLIVRGGVGLDNIDVKYAQANGIKVMNTPNASSIS
                     VAELTIGQLFVLARFINTANVTMRDGKWEKKKYKGTEINGKTLGLIGFGRIAKEVAKR
                     AELLGMNVIYTDIMGEAQGFNNYKFCDMEEVLENADFLSLHIPFDKNKGAVITEKEIN
                     KMKKGAYLINCARGGLVDEKDLLKALDEGKLSAAAIDVYEQEPTLNLDLVNHPRVSPT
                     PHIGASTVEAQERIGDEIVNVIQDFFLDFNNLIGVAL"
     gene            complement(2689..3765)
                     /locus_tag="PC465_003728"
     CDS             complement(2689..3765)
                     /locus_tag="PC465_003728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HDF2650992.1"
                     /translation="MSKKLFIPGPIDVKEEVLQKMATPMIGHRGKDASMLQKSISEKM
                     QKLFYTNNTILLSTSSGTGLMEGSIRSCTSKKAAVFSCGSFGDRWYKMAVANNVPADI
                     FKVELGEATTPEMVDKVLSTGEYDLITVTHNETSTGIRNPIEEIGEVVKKYEDVIYCV
                     DTVSSAGGIKVEVDKIGIDICITSVQKALGLPPGMSICTFSQKAIDRAKQVPFRGVYL
                     DLLAMYEYLIKKNYQYPSTPSLSHMFALDFQLDNILDEGLDNRFNRHEDMANLVRNWA
                     KKHFQIFTNENHLSNTLTVIENTQGISVSNLNSKLQERGFQIANGYGDLKEKTFRISH
                     MGDYTVEDVQELLDNIDDILGFNK"
BASE COUNT         1201 a          726 c          420 g         1638 t
ORIGIN      
        1 aatacacatt taaaacctta taaatataca aatacaatta tatgaatttt catcctcaat
       61 tatagcatag aatatgacta tctatatcct aaaattatcc atttctaaaa aaaaggtaac
      121 tattattaag aatatcaact tatagaattt atattccaca tacgattttc aatcaaaaaa
      181 acaagggcta aaaagtgaat tgtgcacttt ttagcccttt attaattatt catttatttc
      241 atgtaagaat agaccacatc ttactttagg ttcaaaccat gttgacttag ctggcattat
      301 cttatttgca tctgctactc ttattaaatc ttcaatacta gtaggataca ttgcaaatgc
      361 tactttcata tcttcattaa ctcttttttc taattcttca agacctctaa ttccaccgat
      421 aaaatcaatt cttttatcta ctctaggatt atcaattcct aaaatagcat caataacata
      481 gtcttgtaat atagaaatgt ctaatgaatc aacagggtct tctatttcta ataaattttt
      541 atttgctttc attttatacc acttatcacc taggtacatt ccgaaagttc cttttttgtc
      601 aggtttatat ttttcttttc cttctatttc ttctagttca aaattttctt ttattttatt
      661 tataaattct tcctcgctta aaccatttaa gtctttgata accctattat aatccaaaac
      721 cattaaattc tcatctggtg caatcattgc tatgaagtaa ttaaattctt cttttccagt
      781 ataatttgga tttttagctc tcatttcttt ggctacattt tctgctgaag ctgtcctatg
      841 atgaccatct gcaatgtata gataatctaa tttttcaaat ttatctacta ggttatctat
      901 tatatcatca ttatcaatct tccatactgt atgctctatc ttgtcatctg ttatgaaatc
      961 atataaaggt tcattattat ccataaaatc attgattata tcatctatca tcctttgatg
     1021 tttgtaagtt acaagtatag ttcccgtatt agcatcacag tattttatgt gtttagttct
     1081 atcaatttcc ttttctggtc gagtgtactc atgttttttt attgttccat tcaagctttc
     1141 atcaactgat atacatgcta ctataccaac ttgagctcta ccatccatga tttgtttata
     1201 tatatatata cactctttgt catcttttac tagaatttct tgttttcgaa actcatctaa
     1261 attttctcgc gcttttaaat aaactttttc atcatataaa tctatatttt catctaaatc
     1321 aatttctgat ttatctatat gcaaaaatga atatggattc ccttctgcaa ttcttctagc
     1381 ttctttacta ttcataacat cgtaaggaag tgctgctact ttatctacta tatatttatt
     1441 tggtctaatc gccttaaatg gtttaatcgt tgccattact aatttcctcc taattataca
     1501 aaatatttta taatgctacc cctattagat tgttgaagtc aagaaagaaa tcttgaatca
     1561 catttactat ttcgtctcct attctttctt gagcttctac tgtagatgcc ccaatatgag
     1621 gtgtaggaga aactcttgga tgatttacta agtctaaatt taatgtaggt tcttgttcat
     1681 aaacatctat agcagctgct gataatttac cttcatctaa tgcttttagt aaatcttttt
     1741 catcaactaa accgcctctt gcacagttta ttaaataagc ccctttcttc atcttattta
     1801 tttctttttc agttattact gcccccttat tcttatcaaa tggtatgtgt aaagataaga
     1861 aatctgcatt ttctaaaact tcttccatat cacagaattt ataattgtta aagccttgcg
     1921 cctcacccat tatgtcagta tatataacat tcatacctaa taattctgct ctctttgcaa
     1981 cttcttttgc aattcttcca aaacctataa gtccaagtgt ctttccatta atttctgtac
     2041 ctttatactt tttcttctcc cattttccat ctctcatagt tacatttgca gtatttatga
     2101 atcttgcaag aacaaataat tgacctattg taagttctgc aacagatata ctgcttgcat
     2161 ttggagtatt cataactttt atgccattag cttgagcata tttaacatct atattatcca
     2221 gacctactcc acctcttact atcaacttca actttttacc ctctaatgct ttatctatta
     2281 catctttagt aactttagta gctgaacgta ctacaagtac atcaacatct ttaagtttat
     2341 ctcctaaaac atctttttca taaaactgct ctatcacatt aaaatctaac tctctcaatt
     2401 ttctcgctgc ttctttctct attccatcag taactaatat attatacata acaaactcct
     2461 ccaattttta ttcacttaat ttttccaatt tttatttttt aaagtatttt catcaataaa
     2521 aaactttact taattcaact ttctgtttat ataattttca aaatattttt ttattaaagt
     2581 catatcaaat ttttctattg tttgttaaaa atttaatatg taatttttat aaaatattat
     2641 ttattatata ttctaaattt atcttaaaac atacatattt ttacaatatt atttattaaa
     2701 acctaatata tcatcaatat tatctaataa ttcttgtaca tcttcgacag tatagtcacc
     2761 catatgtgaa attctaaaag ttttttcttt taaatctcca tagccatttg ctatttggaa
     2821 tcctcgttct tgtaattttg aatttaaatt tgatacacta ataccttgag tattttctat
     2881 aacagtaagt gtattggata agtgattttc attggtaaaa atttggaagt gttttttagc
     2941 ccagtttcta actaagtttg ccatgtcttc atgtctgttg aatctgttat ctaggccttc
     3001 atctaatata ttatctaatt ggaaatctaa agcgaacatg tgagaaagag atggtgttga
     3061 agggtattgg tagtttttct tgattaagta ttcatacatt gctaacaaat caagatatac
     3121 tcctctaaaa ggtacttgct tagctctatc gattgctttt tgagaaaatg tgcaaataga
     3181 cattcctggt ggtaatccca gtgctttttg tactgatgtt atacaaatat ctattccaat
     3241 cttatcaacc tcgactttta ttccaccggc tgaacttaca gtatctacac agtagattac
     3301 atcttcatac tttttaacaa cttctccaat ttcttctatt ggatttctta ttccagttga
     3361 agtttcattg tgagttacag ttattaaatc gtattctccg gtagaaagca ccttatcaac
     3421 catttctggc gttgttgcct ctcctaattc aactttaaat atatccgctg ggacattatt
     3481 agccactgcc attttgtacc atctatcacc aaaggatcca caggaaaata ctgctgcctt
     3541 tttggatgta caggaacgaa tggagccttc cattaaacca gttccggatg acgtggataa
     3601 aagtatcgtg ttgtttgtat agaatagttt ttgcatcttt tcacttatac tcttttggag
     3661 catagatgca tcttttcctc tatgtcctat cattggtgta gccatctttt gcaagacttc
     3721 ttctttaaca tcaataggac caggaataaa taatttctta ctcattataa ttcccccctt
     3781 tttagtttgt aatatggata gcgtttttac tgtccttatt tttaataact ataatatcaa
     3841 gctgaattaa ctatgtcaac ataaaattta ttttttatat ataatttatt ttatatattt
     3901 tatgaaaaca ttcattttct accttttcat aagtctgaat tttctgaatt attctctcaa
     3961 aaaaaatata ctttttatct atata
//
LOCUS       DAMJXI010000152         3381 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.162, whole genome shotgun sequence.
ACCESSION   DAMJXI010000152 DAMJXI010000000
VERSION     DAMJXI010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3381
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.162"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(93..458)
                     /locus_tag="PC465_003729"
                     /pseudo
     CDS             complement(93..458)
                     /locus_tag="PC465_003729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423610.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
     gene            complement(479..1558)
                     /locus_tag="PC465_003730"
     CDS             complement(479..1558)
                     /locus_tag="PC465_003730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF917 domain-containing protein"
                     /protein_id="HDF2650993.1"
                     /translation="MRFLTEESVDKIAVGAAVLGTGGGGDPYVGKLVAKQAIKKYGPV
                     KVISLDELDDDALVVPVSGMGSPVITIEKLLSEVELTTPLEIMEKLLNRKVDVIIPIE
                     IGGINSLMPIAVAAKKGLPILDADSMGRAFPEAQMVTFYLEGYEASPAVMSDEKGNSA
                     ILYPVDGIWSERLARTLTVEMGGSSSISDYNLSGAQVKKAAIGNTLTIAETIGGFLLE
                     NKSDSKGAVENILKELRGYKLFEGKVIDIKRELKGGFTRGHAFFAGINEYDGEYSILF
                     QNENLIAKKGDTPLCITPDLIAVLDLETGFPITTERIKYGSRVMVVAFPCNEKWRTEK
                     GIETVGPGYFGYDVEYKTVEELQGK"
     gene            complement(1612..2901)
                     /locus_tag="PC465_003731"
     CDS             complement(1612..2901)
                     /locus_tag="PC465_003731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HDF2650994.1"
                     /translation="MEEEKINYALEQIPENQKRGWVAMFSVLVAIGVDLSSVILGAEL
                     AQSMPMKQAILSVIVGSFFSAILYTTCSLVGSSTSLSTSMITKYVFGEAGAKIFSLVI
                     GVSLLGWFGVQVGFFAQNAQIIIKDIFNLDVSMQILSLIGGLLMMSTAIYGYKAMEKL
                     SVYSVPFLLVLMMLTIFLAFRANGISVDDNMKSTMTFAGGVSLSMSIIIVGAIVSPDI
                     SRWAKSRRDCALSSFLGIQFGNAFMIIVSIVLVKCMGTSDIMRIFITLGIAIPGIIVL
                     TLAQWTTNTSNVYSASLSIALVLKKAPEKVLTIVLGIIATLLAVFGIYEGFIGFLNLL
                     GIVIAPVGGVYTAEYYIVKQELKGFDKGVLYKPIVKRSIVSWIIGILITYLSTYGFIT
                     LTTIAPLDGFIAGFVVQSIIGKVLCSTKNKQEIDKAV"
     misc_binding    complement(3064..3275)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT         1115 a          679 c          370 g         1217 t
ORIGIN      
        1 tatcctatct ctacatatag gtttccctat atgctgacta ttttagctac taactcatga
       61 ctaaagtcac gagtgtgcgt agctattttt taatcaaact catatccacc agataccaat
      121 attgaatcta attctatttt ttctcttaag tcttctggcc aatctataaa tggaagaatg
      181 gcagtagtgg ctggctttcc tattcttatc atagccacat tattaagtct ttttctttct
      241 acaatagcat ttgtacaatg agttgtacca agcatagcat attttattaa tgaatggtca
      301 atcttacttt catctataac tttttttaag gcattgtaaa caccagtttc aacatctttt
      361 gtagttgcca ccttaactga atgaattact tttaattccc catccagtat acaagcatct
      421 gtatttgttc ctccaacgtc aattcctaca cgatacatca aaatttcctc ctaaactttt
      481 attttccttg taattcttct actgttttat attccacatc atatccaaag tatccaggtc
      541 caactgtctc aattcctttt tctgttctcc acttttcatt acaaggaaaa gctactacca
      601 taacacgaga gccatatttt attctctctg tagttattgg aaatccagtt tctaaatcta
      661 atactgctat taaatctggt gtaatacaaa gtggtgtatc accttttttg gcaattaaat
      721 tctcattttg gaataatata gaatactctc catcatactc attaatccca gcaaaaaagg
      781 catgtcctct agtaaatcca cctttcaact ctctcttaat atcaattact tttccttcaa
      841 ataacttgta tccacgcaat tcttttagta tattctcaac agcacctttt gaatcagatt
      901 tattttcaag taaaaaccct cctatagttt cagctattgt aagagtatta cctatagcag
      961 cttttttaac ttgagctcca cttaaattat agtcactaat agaagaactt cctcccattt
     1021 ctacagttaa agttctagct aatctttctg accaaattcc atccacagga taaaggatgg
     1081 cagaattacc tttttcatca gacattacgg caggagatgc ctcatatcct tcaagataaa
     1141 aagttaccat ttgagcttca gggaaagctc tacccataga atctgcatct aagataggaa
     1201 gtcctttttt agcagcaact gctataggca taagtgagtt tatccctcct atttctatag
     1261 gaattataac atccactttt ctatttaata atttctccat tatttctaaa ggggtagtta
     1321 actcaacttc tgaaagtaat ttttctattg taattacagg agaacccata ccagatactg
     1381 gaactaccaa agcatcatca tcaagttcat ctaaacttat tacttttaca ggaccatact
     1441 ttttaatggc ttgttttgca accaatttac ctacatatgg gtcacctcca cctccagttc
     1501 caagcactgc tgcaccaact gctattttat ctacactttc ttctgttaaa aatctcatgt
     1561 tactttctcc tcatatttct aatttatttt atactttata aacaaatttc tttatactgc
     1621 tttgtctatt tcttgcttat tttttgttga acaaagcact tttccaataa tagattgtac
     1681 tacaaaccct gctataaaac catctaaagg tgctatagta gtaagagtta taaatccata
     1741 tgttgaaagg taagttatta atataccaat tatccaagac actattgaac gtttaactat
     1801 tggtttatat aatactcctt tatcaaagcc tttaagttct tgctttacta tgtaatattc
     1861 tgctgtatat acaccaccaa caggtgcaat tacaattcca agtaaattta aaaatcctat
     1921 aaaaccttca tatattccaa atacagccaa taatgttgct ataataccaa ggactatagt
     1981 taatactttc tcaggagcct tcttaagtac aagagctata cttaatgatg ctgaatatac
     2041 attacttgta tttgtagtcc attgtgctaa tgtaagtact attatacctg gtatagcaat
     2101 tcctaatgta ataaaaattc tcataatatc tgaagttccc atacatttta ctaatactat
     2161 cgaaactatt atcataaaag catttccaaa ttgtattccc aaaaagcttg aaagagcaca
     2221 gtctcttcta cttttagccc aacgacttat atcaggagat acaattgcac caactattat
     2281 tatactcatt gacagagaaa ctccacctgc aaatgtcata gtagatttca tattatcatc
     2341 aactgaaatt ccatttgctc taaaagctaa gaatatagtt agcatcataa gaactaataa
     2401 aaatggtact gaatacacac tcaacttctc cattgcctta tatccataaa ttgcagtact
     2461 catcatcaag agaccaccta ttaggcttaa aatctgcata cttacatcta aattaaatat
     2521 atcttttatt attatctgtg cattttgagc aaagaaacct acttgaactc caaaccaacc
     2581 taatagagaa acccctataa ctagagaaaa tatttttgct ccagcttctc caaatacata
     2641 ctttgttatc atagatgtag ataaacttgt agatgaacca accaaagagc atgtagtata
     2701 caaaattgca gaaaaaaatg aaccaacaat tactgacaat attgcttgtt tcattggcat
     2761 actctgtgcc aactcagcgc ctaaaataac agatgataaa tccacaccta ttgctactaa
     2821 aactgaaaac atagctaccc aaccacgttt ttgattctct ggaatctgtt ccagagcata
     2881 gttaattttt tcttcttcca ttttcatccc tccatttaaa tcgtaaaact actgacctta
     2941 gcatatttta caattttcta atttataaat ttattaacta tcatattttt ataattttca
     3001 tttaatatat agttttaaat tttctgaaat aagtttataa taaaaaacgc ctcttggaaa
     3061 aatccaagag acgaatataa atccgtgtta ccactcttat tagtaaaaat taattttact
     3121 cactcatttt cttaaggcga attaaaccac tattctaaca taattacaat agtattctcc
     3181 aaagtccttt tcacataaat tccaatatta gttctcagcc aaatctaact ctctgtaaaa
     3241 ttcctttatg ctactttctt cttctacgaa tatataatat tgatttgtag ttaatttatg
     3301 atttatatca taatatatat gcaatatttt gtcaacttaa aaagtcaatt acttgcattt
     3361 tttaatttta tatgtaaatt t
//
LOCUS       DAMJXI010000153         3321 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.163, whole genome shotgun sequence.
ACCESSION   DAMJXI010000153 DAMJXI010000000
VERSION     DAMJXI010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3321
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.163"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(56..628)
                     /locus_tag="PC465_003732"
     CDS             complement(56..628)
                     /locus_tag="PC465_003732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000265278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF2650995.1"
                     /translation="MWIYQKTIQHPVNIKTCDPRMAKFLITQFGGPNGELAASLRYLS
                     QRYTMPTGNMRALLTDIGTEELAHVELICTMVYQLTSDASPEELKAAGLGSNYAQNGY
                     GIYPTDSNGVPFDVRPIAVMSNPVTDLHEDMAAEQKALATYYQLINLTDDVDVIDVLK
                     FLGQREIIHYQRFGEALMDAYELEESQKMF"
     gene            complement(657..923)
                     /locus_tag="PC465_003733"
     CDS             complement(657..923)
                     /locus_tag="PC465_003733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HDF2650996.1"
                     /translation="MKDSSRAELMRKVQETSFACVDMNLYLDNHPDDKNAINTYNSLC
                     NQFAQARYAYENKYGPLTNFGYAPSRCPWQWADQPWPWDREFNY"
     gene            complement(923..1132)
                     /locus_tag="PC465_003734"
     CDS             complement(923..1132)
                     /locus_tag="PC465_003734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HDF2650997.1"
                     /translation="MENKTRDIKKNCGPSLARPYINNQIFTEMYCLSDALKFGTIFPE
                     LNLLESEMYNKELYAKPKKYRGGRR"
     gene            1401..2261
                     /locus_tag="PC465_003735"
     CDS             1401..2261
                     /locus_tag="PC465_003735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HDF2650998.1"
                     /translation="MSELSGKGCEIIVPFEERLPVRDIEKSIIKKYRKNLWSKFMKAI
                     RDYKLVEEGDKIAVAISGGKDSILMAKMFQELKKHGQVNFDVEFIAMDPGYHANIRQL
                     LIDNCEYLNIPIHLFDSRIFEIADEIAKDYPCYMCARMRRGALYSKAEELGCNKLALG
                     HHYDDVIETTMLNLLCAGNFKTMLPKLNSTNFEGIKIIRPLYYIREEHIIRFIQNSGI
                     WPLNCACMVAAKKTGNKRYEIKDLIKSLESNFKNVEKSIFKAAENVNLDSVLGWQKDG
                     EKHSFLENFE"
     gene            2309..>3321
                     /locus_tag="PC465_003736"
     CDS             2309..>3321
                     /locus_tag="PC465_003736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HDF2650999.1"
                     /translation="MKRVYIDFEMNMPNSKSKRAVFNSDIIAIGAVMYDEKTKNIDKF
                     KSLIRPVSNEELYPHIQELTHISSEELKSAPSYEEVMRKFKKWLGIFSDIKGIYTFGN
                     LDLTCFNNTDMRSAKKNNHPRFVNNIRDLFVDIKEKYINCGMRCMNYISLKNLLEFVN
                     LEFSGDAHDPLNDAYNLFILDEAITNNVDIQNLLIIRDIIRPPFNDINSNLDNCFNKF
                     KESLYKKEGNYNIVDFSVEIIKTVRMYLLTIIDVNIQNLEIMKDISKKMDTIDKLKDI
                     EEGYFYLLEDVYFDMKDVLEDLMLYRMNEDEYKYEIKNIIKMFDEDLDNEKIYINKCN
                     NLNV"
BASE COUNT         1286 a          377 c          541 g         1117 t
ORIGIN      
        1 aacacaacag taaattataa attatcaaat aataatagtt atacaaataa aaattttaga
       61 acattttttg agattcttct aactcgtaag catccattaa agcttcacca aatctttgat
      121 agtgaattat ttctctttga cctaagaatt ttaatacatc tataacatca acgtcatctg
      181 ttaggtttat aagttgataa taagttgcaa gtgctttttg ttcagctgcc atatcctcat
      241 gtaaatcggt tacgggattt gacataactg ctataggtct tacatcaaat ggaacaccat
      301 ttgaatctgt tggataaatt ccatatccat tttgagcata gtttgaacca agacctgcag
      361 cttttaactc ttctgggctt gcatcagaag ttaactgata aaccatagta catataagct
      421 caacgtgagc tagttcttct gtaccaatat ctgttaaaag tgcacgcata ttaccagtag
      481 gcattgtata tctttggctt aaatatctta aagatgcagc aagttctcca tttggcccac
      541 caaattgagt tataagaaat ttagccattc tagggtcaca agtttttata ttaactgggt
      601 gttgtatagt tttctgatat atccacatga attttcaatc ctccaatact tgatgtctaa
      661 taattaaatt ctctgtccca aggccaaggt tggtcagccc attgccaagg gcatctactt
      721 ggagcatacc caaagttagt taaaggaccg tatttatttt cgtaagcata tctagcttgc
      781 gcaaattgat tacataatga attataagtg ttgatagcat ttttatcatc agggtgattg
      841 tctaaatata agttcatatc aacacatgca aaagatgttt cctgaacttt tctcataagt
      901 tcagctctag atgagtcttt cattatcttc tacctcctct atattttttt ggcttagcat
      961 ataattcttt gttgtacatt tcagactcta gtaagtttag ttctggaaat atagttccaa
     1021 attttaatgc atcagaaagg cagtacattt ctgtgaaaat ttgattatta atgtatggtc
     1081 tagccaaaga tggaccacaa ttttttttga tatctctagt cttattttcc aagatgaaaa
     1141 cctccttgtt gtaaatagat aggtaactct atctagtgta taatattcaa tcatttaaaa
     1201 atcgttacta ataataaaat attaaatgag aaaaataaaa aagataataa aagaaagagg
     1261 ttatttatgt tattataagt ttatgtgtta ttgtaaacta taaattattt agtaaaatta
     1321 aagtaaaaat tatagtattt tgtggatgaa ggtagacttt tttgtaaaat attattaaca
     1381 taaatatacg aggtgattag atgagtgaac tatcaggaaa aggctgtgaa attatagttc
     1441 cttttgagga aagacttcca gtaagagata tagaaaaaag tataataaaa aaatatagga
     1501 aaaatttatg gtctaagttt atgaaggcaa taagagatta taaattggtt gaagaaggtg
     1561 ataagatagc tgtagcgatt tctggtggaa aagacagtat tcttatggct aaaatgtttc
     1621 aagagttaaa aaaacatgga caagttaatt ttgatgttga atttattgct atggaccctg
     1681 gatatcatgc aaatataaga caattactta tagataattg tgagtatcta aatataccaa
     1741 tacatttatt tgattcaagg atatttgaga tagcagatga aatagcaaaa gattatccat
     1801 gctatatgtg tgcaagaatg aggagaggag cattatattc aaaggcagaa gaattagggt
     1861 gtaacaaact tgcattaggt catcattatg acgatgtaat agagacaaca atgcttaact
     1921 tattatgtgc tggaaatttt aaaacaatgc ttcctaaact taattctact aattttgaag
     1981 gtataaaaat tataagacca ctttattata taagagaaga acatattata agatttattc
     2041 aaaatagtgg tatatggcca ttaaattgtg catgtatggt tgctgctaaa aaaacaggta
     2101 ataaaagata tgagataaaa gacttaataa agagtttaga atcaaatttt aaaaatgtag
     2161 aaaaatctat atttaaggcg gcagaaaatg taaatcttga ttcagtactt ggttggcaaa
     2221 aagatggaga gaaacattct ttcttagaaa attttgaata aaaatagtta aaaagaatca
     2281 ctataaacaa ttggaaaggg tgtttatatt gaaaagagta tatatagatt ttgaaatgaa
     2341 tatgccaaat tctaaatcaa aaagagcagt atttaattct gatataattg caatcggagc
     2401 agttatgtat gatgaaaaaa caaaaaatat tgataaattt aaatctttaa taagaccagt
     2461 aagtaatgag gagttgtatc ctcatataca agaattaaca catatatctt ctgaagaatt
     2521 gaagagtgca ccaagttatg aagaggtcat gagaaagttt aaaaaatggc ttggcatatt
     2581 ttctgatatt aaaggaatat atacttttgg taatttggat ttgacatgtt tcaataacac
     2641 agatatgaga agtgctaaaa aaaataacca tccaaggttt gtaaataaca ttagagattt
     2701 atttgtagat ataaaagaaa aatatataaa ttgtggtatg agatgtatga actatatatc
     2761 attgaaaaat ttacttgaat ttgttaactt agagtttagt ggagatgccc atgacccatt
     2821 aaatgatgca tataatttat ttattttgga tgaggcaatc acaaataatg tagatataca
     2881 aaatctttta ataatacgtg acataataag accaccattt aacgatataa attctaattt
     2941 agataattgt tttaacaaat ttaaggagtc attatataaa aaagaaggaa attataatat
     3001 tgtagatttt tctgttgaaa taataaaaac tgtgagaatg tacttattaa caatcataga
     3061 tgtaaatata caaaatttag aaattatgaa agatataagt aaaaaaatgg atactataga
     3121 taaattgaaa gatatagagg aaggctattt ttatttatta gaagatgtgt acttcgatat
     3181 gaaagatgta ctagaagatt taatgcttta tagaatgaat gaagatgagt acaagtatga
     3241 gataaaaaat ataataaaaa tgtttgatga agacttagat aatgaaaaaa tatatataaa
     3301 taaatgtaat aacttaaatg t
//
LOCUS       DAMJXI010000154         3311 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.164, whole genome shotgun sequence.
ACCESSION   DAMJXI010000154 DAMJXI010000000
VERSION     DAMJXI010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3311
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.164"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            101..1270
                     /locus_tag="PC465_003737"
     CDS             101..1270
                     /locus_tag="PC465_003737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HDF2651000.1"
                     /translation="MNKLCKDEVVEFCNRIKGKVESVAISGVFAPVNKQQEEEVAKWV
                     REILGDIPISLSNEIGNIGILERENGAILNSALSQVGKAVSLGFEKALKDLGIDAQIY
                     FSQNDGTLMNLEYTMKYPIFTIGCGITNSIRGASFLSKVKNAIVLDVGGTTSDLGVLY
                     NGFPRESSIPVTIGGVHTNFRMPDVLTIGLAGGTCVKGEKDNIKIGPESVGYRITEDA
                     IIFGGDTLTLSDVVTKLDMAFEDRKSNVENLDKEYCNEVYKKVILKLEDAVDQMKTSQ
                     DDVELVLTGGGSIIVPEKLKGISNVIRPPHYTAANAIGAALGQISGDVEKVYSLDKMS
                     REDAIEDAKKEAVNKALKAGAKEDTIEVLNIEDVPLAYLPGNALLIKVKVVGDLI"
     gene            complement(1433..1975)
                     /locus_tag="PC465_003738"
     CDS             complement(1433..1975)
                     /locus_tag="PC465_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HDF2651001.1"
                     /translation="MKSYIALLRGINISGKNKIIMSELKASFVELGYSEVSTYLNSGN
                     VVFLSDVDDSKVISNTIRLMIKKQFELEIPVFIISQEELKDILNNAPNWWGDNNKEIY
                     DNLIFMFPDLSYDEFYDEVGNPKEEYEKVYHYKNAIFWSFSRKDYKKTNWWSKTASSN
                     VSDKITIRTANTVRKIVGMR"
     gene            complement(2123..2407)
                     /locus_tag="PC465_003739"
     CDS             complement(2123..2407)
                     /locus_tag="PC465_003739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2651002.1"
                     /translation="MAKNTKQTTVHIDETLLKEVKRIGINENKSISQIINESIIDYIL
                     VYRENEDKEKNEHDKNLNETINEFKKEEEKRMQAKSAARAIAEAKKRVLY"
     gene            complement(2470..3234)
                     /locus_tag="PC465_003740"
     CDS             complement(2470..3234)
                     /locus_tag="PC465_003740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HDF2651003.1"
                     /translation="MNNYLKFATYQLIGFTSSIPRLIKIKKNPDKFSLKEKFEFMQKQ
                     AKKSLDIVNIELNIIGKETLPKEPLLFVVNHSSMLDSFILTASVERPIGCVIADEPVW
                     RNIPIFKEWAKLLRCVYVNRKNNREGIKSITQASQNILTGQSMAVFPEGDLTWIKEPN
                     SLVSEFRSGALKIAYKAKCPIVPLVIKNSKDTYEGYQPIGKINSVPVEVEFLEPIYDH
                     IENPRLKSSVLGENIKNKMINTIENFRKSNKTFKEF"
BASE COUNT         1111 a          457 c          494 g         1249 t
ORIGIN      
        1 gggatagcct gtggagaatt agtaagacat attttagtat gcaaaattct gtgaagcagg
       61 aaccctgtga ctttagtcat gggaggttca gggtagaaag ataaataaac tttgtaaaga
      121 tgaagttgta gagttttgca atagaataaa aggtaaagtg gaaagtgttg caataagtgg
      181 agtatttgct ccagtaaata aacaacaaga agaagaagtt gcaaaatggg ttagagaaat
      241 tttaggggat attcctatat ctttatcaaa tgaaataggt aatataggta tattagaaag
      301 agaaaatgga gctattttaa attctgcatt gtctcaagta ggtaaagctg tatctttagg
      361 atttgaaaaa gcacttaaag acttaggtat agatgctcaa atatatttca gtcaaaatga
      421 tggaacatta atgaatttag agtatacaat gaaataccca atttttacaa ttggatgtgg
      481 aataacaaat tctataagag gagcttcctt cttatcaaaa gtaaaaaatg caatagtatt
      541 agatgttggt ggaactacaa gcgacttggg tgtactatat aatggattcc ctagagaatc
      601 atctattcca gttacaattg gaggagtaca tacaaacttt agaatgccag atgttttaac
      661 tattggtctt gctggtggta catgtgtaaa aggcgaaaaa gataatataa agataggtcc
      721 tgaaagtgtg ggatatagaa taactgaaga tgcaataata tttggtggag acactctaac
      781 tttatcagat gttgttacaa aattagatat ggcgtttgaa gatagaaaaa gcaatgttga
      841 aaacttagat aaagagtatt gtaatgaggt atataagaag gttattttaa aattagaaga
      901 tgctgtagac caaatgaaga ctagtcaaga tgatgttgaa ttggttttaa ctggtggagg
      961 aagtataatt gttcctgaaa aactaaaagg cataagcaat gttataagac ctcctcatta
     1021 tactgctgca aatgctattg gtgcagcttt aggacaaata agtggagatg tagaaaaagt
     1081 atacagttta gataaaatgt cgagagaaga tgccatagaa gatgcaaaaa aagaggctgt
     1141 aaataaagct ctaaaagctg gtgctaaaga agatactata gaagtattaa atatagaaga
     1201 tgttccactt gcataccttc ctggtaatgc acttcttata aaagtaaaag ttgttggtga
     1261 tttaatttaa agaataaata taagtatttc cagaattata taaatatttc tggactcatt
     1321 tttaaactta ttttatcaat aaaaacagca taacttttga ctatattctt ataagtttcc
     1381 gaacagccga tatataccta ttttttgagg tttatcggct gtttgttatc ttttatcgca
     1441 ttccaactat ttttcttacc gtatttgctg tacgaattgt aatcttatca cttacatttg
     1501 aactggcagt ctttgaccac caatttgtct ttttataatc tttacgacta aaagaccaaa
     1561 agatagcatt tttataatga tatacttttt catactcttc tttaggattt ccaacctcat
     1621 cataaaactc gtcataagat aagtcaggaa acataaaaat aagattatca tatatttctt
     1681 tgttgttatc tccccaccaa ttaggagcat tatttagtat atcttttaac tcttcttgtg
     1741 aaataataaa aactggtatt tccaattcaa actgtttttt tatcattaat cttattgtat
     1801 ttgagataac cttgctgtca tctacatcac ttaaaaagac aacattacca ctattaaggt
     1861 atgtagaaac ttctgaataa ccaagttcta caaagcttgc ttttaattca gacataatta
     1921 tcttgttctt accacttata ttgatacctc ttaataatgc gatataactt ttcatataat
     1981 aatttcacct ctaaatattc acatttttct atgtagtaca aactggaatt tgcatctttt
     2041 ataattcttt caaaacttct tcatatgtaa tttttttaat ataaaaaaat cggtgcttaa
     2101 tttgtaccga tttttgtttt tcttagtaaa gaactcgttt ttttgcttct gctatagctc
     2161 tagcagcact ttttgcttgc attctttttt cttcttcttt tttaaattca tttattgttt
     2221 catttagatt cttatcatgt tcattttttt ctttatcttc gttttctctg tatactaata
     2281 tataatctat tattgattcg tttattatct gagatatact tttattttca ttaattccta
     2341 ttctcttaac ttccttaagt agagtctcat caatatgaac cgttgtttgc tttgtatttt
     2401 ttgccacctt aatcacctct taaaaaaaat tctaacatta aaattttttt tagtcaataa
     2461 attttaatat taaaattctt taaatgtttt atttgatttt ctaaaatttt ctattgtatt
     2521 tatcatctta ttttttatat tttcacctag tacagaagac tttagtctag gattttcgat
     2581 atggtcataa attggttcta aaaattcgac ttcgacagga acagagttaa ttttaccaat
     2641 aggttggtat ccttcataag tatcttttga attttttatt actagtggaa caatagggca
     2701 ttttgcttta tatgctatct ttaaagctcc acttctaaac tccgaaacca atgaatttgg
     2761 ttctttaatc catgttaaat ctccttctgg aaacactgcc atactttgac ctgtaagtat
     2821 attttgagag gcttgggtta tactctttat accctcacga ttgttttttc tgtttacata
     2881 tacacatctt agtaattttg cccattcttt aaatataggt atatttctcc aaactggttc
     2941 atctgcaatt acacatccaa ttggtctttc tacacttgct gttagtatga agctgtcaag
     3001 catactagaa tgatttacaa caaatagaag tggttctttt ggcagtgttt ccttaccaat
     3061 tatattaagc tctatgttca ctatatctaa agatttttta gcttgttttt gcataaattc
     3121 aaatttttcc tttaagctaa atttatcagg attcttttta attttaataa gcctaggtat
     3181 agaagatgta aaacctataa gttgatatgt agcaaatttt aagtaattat tcataaaatt
     3241 atctccttaa aataaaatta tttattactg taaagatttt aacataaaat aaaatttaag
     3301 tctattttaa t
//
LOCUS       DAMJXI010000155         3060 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.165, whole genome shotgun sequence.
ACCESSION   DAMJXI010000155 DAMJXI010000000
VERSION     DAMJXI010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3060
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.165"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            168..1061
                     /locus_tag="PC465_003741"
     CDS             168..1061
                     /locus_tag="PC465_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDF2651004.1"
                     /translation="MKNKKFIVIILIISILIGVLVKEYSSREIKKDDINVSKYIKYAD
                     LASKNNAQVNWKYVASIVAVLNKNNLKNVKDSQIQEVSDLFVKNFSKNNKINKLSDIL
                     DELEFSNRQKRLVDNYIDNLKDYGIKPERLKSDTKYMKFIDEIKTEAIQNYKDYKILP
                     SITIAQAIIESSWGKSTLAKQYNNLFGIKADAYWKGKSVTLETKEHLDTIIDDKFRIY
                     DDKNESIKDHAKFLATNKRYKNNGVFDAKTYIYQAKALEKAGYSTAKDENGNSIYAAR
                     LIELIQQYNLQLIDSEIQSEM"
     gene            1504..1994
                     /locus_tag="PC465_003742"
                     /pseudo
     CDS             1504..1994
                     /locus_tag="PC465_003742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861486.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2022..2969
                     /locus_tag="PC465_003743"
     CDS             2022..2969
                     /locus_tag="PC465_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651005.1"
                     /translation="MRITKTTFNDVFSNDANGSIIKVEKYVDKKCASVFEILTYTIIV
                     TNTSRYKTGNIFFKDYISKYIEFINNTVKVNGIIKRGLDPQKGFYIGRIDASCKKIIS
                     FKSVVLPNSAHRIIKNSANIYYYYKCNLDKFPTRISIESNRVYTNVNKIVFKQLNISN
                     TLKAPKNLRDILKVNVNSKIFDVKPMKNLINKGSNLKLCNLIVFGCIEVEIDYSCKNR
                     SNFKTVNKSNDIKKDKYYKNDIQNNNENINDCKKQISFGDNKVKKITKTFGFSCFICS
                     PVGIIYEDMKNINIKIEHTSINELNPEELFVNTSLLLYY"
BASE COUNT         1339 a          262 c          430 g         1029 t
ORIGIN      
        1 attttaacta ttttgtgtga tagaaaacta tatattataa caatagtagt gcttttaatt
       61 aaatatattt cataaatctt cataaaatct tcaaaatttc gtaaagaata tgtcacaaaa
      121 gtaaggtata ttatattcag cagatagtat aagggaggac aatatttatg aagaataaaa
      181 aattcattgt tataatactg ataatatcaa ttttaatagg tgtattagtg aaggaatatt
      241 catctagaga gataaaaaag gatgatataa atgtcagtaa gtatataaaa tatgctgatt
      301 tagcaagtaa aaataatgca caagttaact ggaagtatgt agcttccatt gttgctgtgt
      361 taaataaaaa taacttaaaa aacgttaagg attcacagat acaagaagta tcagatttat
      421 ttgttaagaa tttttctaaa aataataaaa taaataagtt aagtgatatt ttggatgagt
      481 tagaatttag taatagacaa aaaagattgg ttgataatta tatagacaat cttaaggatt
      541 atggtataaa accagaaaga ttgaagtctg atacaaaata tatgaagttt attgatgaaa
      601 ttaaaacaga agcaatacaa aattataagg attataaaat acttccatct ataactattg
      661 cacaagctat aatagaatct agctggggca agtcaacttt ggcaaaacaa tataacaatc
      721 tatttggtat aaaggctgac gcttattgga aaggtaagtc agtgacttta gaaacgaaag
      781 aacatttaga tacaattata gatgataaat ttagaatata tgatgataaa aatgaatcta
      841 taaaagacca tgcaaaattt ttagccacaa ataaaaggta taaaaacaat ggtgtatttg
      901 atgcaaaaac gtatatatat caagctaaag cattagaaaa ggcaggttat agtactgcga
      961 aggatgaaaa tggcaatagt atatatgcag ctcgtctaat agaattaatt caacagtata
     1021 atcttcaatt aatagacagt gaaattcaaa gtgaaatgta actttgatta aatttttatt
     1081 gataaggcta tgatttttaa aatcatagcc ttattttgac atgtttttac ttttaattat
     1141 taaatcgata tcattatctt tcaaaattta ctttatactg taaattaaat tatttaagtt
     1201 aaaacttgga attatttata aaaggattat ttactttatc taaattctgc acttaaagaa
     1261 catcttttcc cttaagactg accgttagtc tataaaaatt ataattactt ataaaaaagt
     1321 gaatagagag atatatatat aattttcaga aagactttta cttgtaaatt gaaattaatg
     1381 aagtaaaaaa ggattctttc ttaaaagtaa ataacaacta gatagtgaat aataaaaaat
     1441 ggtaatttga aataattttt atgaatagta ttaatatata gatacaggga gattgatgcg
     1501 attatgtatg aaaataataa ggtaatatac aaccttgaaa gatgtgaaaa actagaaaag
     1561 actctttatt tatctcaatt taatacatat aaaaatttta aattagcttc taaaaaaact
     1621 gtaataaatt cattagagac atatgtttac aatatgaata ttaacaatat aagtcttgtt
     1681 gatactatag aatgtatatc attagaagat gaacaactta caggaaagaa gttgatttta
     1741 gttggtgata tagatattga tgcaatatta gattatgcag gaaataaaag aaatagaaat
     1801 tctagtaaaa aaatacattt aaattaaaaa taccctttag tacatttata caaatgccta
     1861 gaaagataga aaataaagat aaaattaatt taaagtatct tatacaagat attacttcat
     1921 ctattttaga tgataattta tttattagtg ttactgcaat tataagttat gaaaatagtt
     1981 ccaagataga gtaatcttta aattatagaa aggtggatgc aatgagaata acgaaaacta
     2041 cttttaatga tgtattttca aatgatgcaa atggaagtat tataaaagta gaaaaatatg
     2101 ttgataaaaa atgtgcatct gtatttgaga ttttgaccta cactattatt gttacaaata
     2161 caagtaggta caaaactgga aatatatttt tcaaagatta tatttctaaa tatatagagt
     2221 ttataaataa tactgtaaaa gttaatggca ttataaaacg tggattagac ccacagaaag
     2281 gtttttacat agggagaata gatgcaagtt gtaaaaaaat aatatctttt aagagtgtag
     2341 ttttaccaaa ttctgcacat aggattataa agaatagtgc taatatatac tattattata
     2401 agtgtaatct agataaattc ccaacaagaa tatcaataga aagtaataga gtttatacta
     2461 atgtaaataa aattgtattc aaacaattga atataagtaa tactttaaaa gctcctaaaa
     2521 atctaagaga tatattaaaa gtaaatgtaa atagtaaaat atttgatgtt aaacctatga
     2581 aaaatcttat aaacaaaggt agtaatttga aattatgtaa cttgatagtt tttgggtgta
     2641 tagaagttga aatagactat agttgtaaaa ataggagtaa ttttaaaaca gtaaataagt
     2701 ctaatgacat taaaaaagat aagtattata aaaatgatat acaaaataac aatgaaaata
     2761 taaacgattg taaaaagcaa ataagttttg gtgataataa ggtaaaaaaa ataacaaaaa
     2821 cttttggatt ttcttgtttc atttgttctc cagttggaat tatttatgaa gatatgaaaa
     2881 atataaatat aaaaattgaa catacatcaa taaatgaatt aaatccagaa gaattatttg
     2941 taaatacatc acttttattg tattattaag tattttaaag ctaaaactta aacttattaa
     3001 aatagcattt ggttaaagga aaatagatat tgatatattt atcatagata taaatgatta
//
LOCUS       DAMJXI010000156         3001 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.166, whole genome shotgun sequence.
ACCESSION   DAMJXI010000156 DAMJXI010000000
VERSION     DAMJXI010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3001
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.166"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     regulatory      82..175
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            258..743
                     /locus_tag="PC465_003744"
     CDS             258..743
                     /locus_tag="PC465_003744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF2651006.1"
                     /translation="MISELMLKNFRKSSINFKTKIKLNLREKPDINSLKLKSIPEGKI
                     VKLKCVDGIWAEVESNYDKGWLLYKYLERLSNAKNNSNDTIKNRKKNYIGNIRTNGLS
                     LELRNDRTLESKVITTIPDGFKVEVCYSVGKWARVNINKNEKRYSGYVYNQYIEEHLS
                     L"
     gene            1099..1497
                     /locus_tag="PC465_003745"
     CDS             1099..1497
                     /locus_tag="PC465_003745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651007.1"
                     /translation="MNKKKKLIGIAISFLLIISIINPLQVEAEAIIESSVYISSIKEN
                     YTYDNTKFKTIKSKSRHKSRKYNKSKVKLKKRSIRTKKYGYQTINKYKRQNARRHNIL
                     TKLILSIIVIFLVIVLVVLIFIKRKKKKFY"
     misc_binding    1933..2196
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            2347..2898
                     /locus_tag="PC465_003746"
     CDS             2347..2898
                     /locus_tag="PC465_003746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan transporter"
                     /protein_id="HDF2651008.1"
                     /translation="MKTNTKKLTLNAILLAMGLLIHQITPAIGLPMKPDVPLAMLFVI
                     LVLNRDDYKTCLIAGIVTGIFTALTSSFPGGQIPNVIDKTLTANIVFLLMNISYNMPF
                     IKKLAKKTQDTVVVAIIMPIGTLVSGTIFLLAAQAIVGLPGASFTALFLAVVLPAVLI
                     NLVAGIFLFKIVSLSIRRVSYQA"
BASE COUNT         1294 a          265 c          441 g         1001 t
ORIGIN      
        1 ttaattaaaa atttaattta tatttaaata atataaaatt tgaggtaata ttatttttta
       61 attgttcaaa ttatgttatt attcagatat aggcaatatt agataaatct aatgacgcaa
      121 aactataggg actaaaatct ttatgtaata aaggtcatgt cagccagttg ccaaaaagat
      181 aataattctt tttgttaaaa gtatttttag agttatatat tttaataact taatatttgg
      241 caagaggagg gcttaagatg atatctgaat taatgttaaa aaattttcgc aaatctagca
      301 tcaattttaa gactaaaatt aaattgaatt taagagaaaa accagacata aatagtttga
      361 aattaaaaag tataccagaa ggtaaaattg ttaagttaaa gtgtgtagat ggaatatggg
      421 cagaagttga gagtaattat gacaaaggtt ggttacttta taaatattta gaaagattaa
      481 gtaatgctaa aaacaatagt aatgatacaa taaaaaatag aaaaaagaat tacataggaa
      541 atataagaac aaatggatta agtttagaac ttagaaatga tagaacatta gaatctaaag
      601 ttataactac aatccctgat ggttttaaag ttgaagtatg ttatagcgtt ggaaaatggg
      661 caagagttaa tatcaataaa aatgaaaaac gatattctgg atatgtatat aatcaataca
      721 tagaagagca tttaagttta taatacgata ctagcaagct ttaaatatat taataaatca
      781 caaaaaagaa tcccattaat gggattcttt tttgtagaaa cattataaca gaactaaaga
      841 gaataaatta actaatttat ttttattata aagtaattat aaatggtaaa tttaattgaa
      901 agtagattta acttatactt tatacaccaa gtatcataaa ttaatactac tttgaaaaat
      961 cttaaaaaaa gtaaaagtta tgataataaa aataatatta aagataataa gatatataag
     1021 aaacttgaaa aaatttgtaa tttttagtta tatatatatt ataatgaact agttaaaaat
     1081 ttttatgagg gggaaaatat gaataagaag aaaaaattga ttgggatagc tatatctttt
     1141 ctacttataa tcagcattat aaatccatta caagtagaag cagaagctat tattgagtct
     1201 agtgtataca tttcttcaat aaaagagaat tatacatatg ataatactaa atttaaaact
     1261 attaaatcta aaagtagaca taaaagtagg aaatataata aaagtaaagt aaagttgaaa
     1321 aaacgaagta taagaactaa aaagtatgga tatcaaacta taaataaata taaaagacaa
     1381 aacgcaagaa gacataatat cctaacaaaa ttaatattgt ccataatagt catatttttg
     1441 gttatagttt tagtagtgct aatatttatt aaaagaaaga agaaaaaatt ttactaaaaa
     1501 taattaaaag aatatcattt ttttaatcat tggtatctat ttaataatat gatgtaatta
     1561 aaatggagta atattctgtt tcaaaggagg catataaata caggaatgag tattaaatga
     1621 tggttaatta agtaaattta ttgataaatg tacttaatta actttgaaga atttaattcc
     1681 tcatgaatca aaatataaaa ttacatcaac agttattcac aaaattaata taagaagaat
     1741 tagagccaaa gagcagacta ttagaccatt aaagtaatta ttcatagaat tttgtatatg
     1801 aaaagaaatg tatagtataa tttacttttt ttataaaaaa tagattacaa aatatatttt
     1861 ttataaaaag gtattgacat tttttagaaa aaagaatatc attattttaa caacaaaatt
     1921 caatacaata aattaaatcc tatgacaagg aagagtagtt aaatttaggt tcagtataga
     1981 gagctgagga tggtggaatc ttagcaagaa aaaatttgat gaatggccct tagaggaata
     2041 aattgaaatc atagttttga gagtagactt tatcgtcagt cgcacgttat agcgaataag
     2101 gtatgtaagt acctgataat gagatgtatg aaaattgaat tttatattaa tttttatata
     2161 atttaggtgg caacgcggat aatctccgtc ctattagttt aggacggagt tttttatttt
     2221 actgaaaatt taaaagatag aaggtggtga gaaagatgtt atgaatttca aaagctaaag
     2281 atgatgatat agtaggttgg caaaaaaata aattgaaaat taaaaaaata ggaggaagta
     2341 caaaaaatga aaacaaatac aaaaaaatta actttaaatg caatactttt agcgatggga
     2401 ttattaatac atcaaatcac accagctata ggattaccaa tgaagccaga tgtaccacta
     2461 gcaatgttat ttgtaatatt ggttttaaat agagatgatt ataaaacttg tttgatagcg
     2521 ggtatagtaa caggaatatt tacagcactt acatcaagtt ttccgggagg tcaaattcct
     2581 aatgtaatag ataaaactct tacagcaaat atagtatttt tattaatgaa tattagttat
     2641 aatatgcctt ttataaaaaa attagctaag aaaacacaag atactgtagt agttgcaata
     2701 ataatgccaa taggaactct tgtaagtgga actatctttt tattagcagc tcaagctata
     2761 gttggtcttc caggggcttc atttacagct ttattcttag cagtagtatt accagctgtt
     2821 ttaataaatc tagttgcagg aatattttta ttcaagattg ttagtctatc aataagaaga
     2881 gttagttatc aagcttaaac acgaaataat attttacttt ataaagcatt ataataacta
     2941 aataacataa gaataaagta gattataact attttattct tatgttgttt aaagatttgg
     3001 t
//
LOCUS       DAMJXI010000157         2986 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.167, whole genome shotgun sequence.
ACCESSION   DAMJXI010000157 DAMJXI010000000
VERSION     DAMJXI010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2986
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.167"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            110..1219
                     /locus_tag="PC465_003747"
     CDS             110..1219
                     /locus_tag="PC465_003747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2651009.1"
                     /translation="MDFKSLGISENTINILKKSGITTPTPIQKESIKLIKEGKDVIAE
                     AQTGTGKTLAFLLPIFENISLDINDIQVLILSPTRELAIQITEEAMKLKESKDVSILA
                     AYGGKDIGSQIKKLKGNIHMIIATPGRLLDHLNRKTIDLSKLKTFVLDEADQMLLMGF
                     KNEVEAILKETSNKKQTLCFSATINSQVKKLAYRYTKNPVVVSIQKEEITLNNIKQEV
                     VETTDRKKLDALCKVLDEDNPFMAIIFCRTKRRVDNLEEALAIRGYNCQKLHSDIAQS
                     KRERIMKSFRNLDIQYLIATDVASRGLDISGVSHIYNYDLPETPEDYIHRIGRTGRAG
                     EEGYTCAFIDPKNERMLSEIETAIESKISRRIIEL"
     gene            complement(1596..2780)
                     /locus_tag="PC465_003748"
     CDS             complement(1596..2780)
                     /locus_tag="PC465_003748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651010.1"
                     /translation="MQKSVKKAKVTGSMLAIFGVASVLFSSHAGGGFATGNQETQYYV
                     QYGWTAPLMAILAMIILTATMREVIIMYNNNNCRNYKDLFCELWRPYPKLEIIWEIYY
                     YLMVLIAVSAVIAGAAAVFQSIGVNYFVAVFIIGVVLLVFTIFGAMLVSKAATAMTIA
                     ILVCTLTIFIVGIKAKVPEITEILSNRTSFTPGYIKPILNTFIYAGFQSVVIPTLAGC
                     SRPLLKNSKEATKAMIISFVMNAIALGLAVTMLMGWYREIIAAGQTTLPTLYVAGQSG
                     NHTIYIIYNVALFLCLMSTGVTTIFGLVNRFEDHKALSFLSSRMKRRVFTACAIMVVS
                     MLISLTGLSNIVKYGYGYCGYLGLFTIVIPFLTLGHYKNKKFAKENPEAKWPAELNEN
                     VN"
BASE COUNT         1138 a          447 c          407 g          994 t
ORIGIN      
        1 ttttaagcta tataaataat aattaaaaaa tttactaaaa atacttataa atatgatatt
       61 attaattggt taataaaaaa gaaaattttt catgaaaggt aagataacaa tggatttcaa
      121 aagcttaggg attagtgaaa atacaataaa tattctaaaa aaatcaggaa taacaacacc
      181 tacacctata caaaaagaaa gtattaaact aataaaagaa ggaaaagatg taatagcaga
      241 agctcaaact ggaacaggaa aaacactagc ttttttactt ccgatatttg aaaatatatc
      301 attagatata aatgatatac aagtacttat actttctcct acaagagaac tagctattca
      361 aataacagaa gaagctatga aacttaaaga atctaaagat gtaagtattc ttgcagcata
      421 tggaggaaaa gatattggtt ctcaaataaa gaaactaaaa ggaaatattc atatgattat
      481 agctacacca ggtaggcttt tagaccatct aaatagaaaa acaatagacc ttagtaagtt
      541 gaagactttt gttttagatg aagcagacca aatgttgctt atgggattta aaaatgaagt
      601 ggaagctatt ttaaaagaga cttcaaacaa aaagcaaaca ctatgctttt ctgcaactat
      661 aaattctcaa gtaaaaaaat tagcttatag atacacaaaa aatcctgttg tagtttctat
      721 tcaaaaagaa gaaatcactc ttaacaatat aaaacaagaa gtagtagaaa ctacagatag
      781 aaaaaaatta gatgccttat gtaaggtact agatgaagat aatcctttta tggcaataat
      841 attttgtaga actaagagaa gggttgacaa tcttgaagaa gctcttgcta taagaggata
      901 taattgtcaa aaacttcata gtgatattgc tcaatcaaaa cgagaaagaa taatgaaatc
      961 atttagaaat ttagatatac aatacttaat agctacagat gtagcttctc gtggtcttga
     1021 tatatctgga gtaagtcata tatataatta cgatttacca gaaacaccag aagactacat
     1081 ccaccgtatt ggtagaactg gtagagctgg tgaagaaggc tatacatgtg cttttattga
     1141 ccctaaaaat gaacgaatgt taagtgaaat agagacggct atagaatcta aaattagtag
     1201 aagaattata gaattataat ttatagattg cttaaaatac caatgccaca caaacactgt
     1261 aatatataga aagctacaga aaacatgtat caatctatac tttgctgtta tactatttta
     1321 tattaaagaa aaaagaggct atccaaagta ggattagtct cttttattgt caaaataatg
     1381 aaaatatatt tgacttcata taaaaaagag tgccttataa actaaaagtc cattttgaga
     1441 caccctcttt ttatctttta ttcttagttt tatattgctt gtttatagtt gtttaatatt
     1501 agattttgca aataatctta ataaacatgc agatatatta tctatagtat tcttatctat
     1561 agtattctct ttagcaatat tttttgctac tacatctaat ttacattttc atttaattcc
     1621 gctggccatt tagcttctgg attttccttt gcaaacttct tattcttata atgtcctagt
     1681 gtaaggaatg gaattactat agtgaataga ccaagataac cacaatatcc atatccatat
     1741 ttaacaatat tacttaatcc tgtaagtgat ataagcattg acactaccat tattgcacaa
     1801 gctgtaaata cccttctttt cattcttgaa gaaaggaaag aaagtgcttt atggtcttca
     1861 aatctattta caagaccaaa tatagtagtt actcctgtag acattaaaca aaggaataat
     1921 gcaacattat aaattatgta tatagtatga tttccagatt gacctgcaac ataaagagta
     1981 gggagtgttg tttgcccagc agcaataatt tctctatacc atcccattag catagttaca
     2041 gcaagtccta atgcaattgc attcataaca aatgaaatta tcattgcctt agtagcttct
     2101 tttgagttct taagaagtgg tcttgaacat cctgcaagtg taggtataac aaccgattga
     2161 aaacctgcat aaataaaagt attaagtatt ggcttgatat agccaggtgt gaaactcgtt
     2221 ctatttgata atatttcagt tatttctggt actttagctt ttataccaac aataaaaata
     2281 gtaagagtac atactagaat agctattgtc attgctgtag ctgctttaga tacaagcata
     2341 gcaccaaata tagtaaagac aagaagtaca actccaataa taaatacagc tacaaaataa
     2401 tttactccta tactttgaaa tactgctgct gcacctgcta taacagcact tacagctatt
     2461 aaaaccatta gatagtaata tatctcccat attatttcaa gttttggata tggtctccaa
     2521 agctcacaaa ataaatcctt ataattccta caattgttat tattatacat tatgataact
     2581 tctctcatgg tagcagtaag tataatcatt gctaaaattg ccataagtgg tgctgtccat
     2641 ccatactgca catagtactg agtttcttga ttccctgtag caaatcctcc tcctgcatgt
     2701 gaactaaaaa gaacgcttgc aacaccaaaa atagctaaca tagagcccgt tacttttgct
     2761 ttctttacac ttttttgcat gaaatcatcc tccctaaaat gatattgaaa gtttttattt
     2821 taacacttta ttgataaaac aataacattt ttgctcatta aattcaacta tatttttcca
     2881 atgactttac attttcaact tatttccacc tttatattaa atatttttta tatatttatt
     2941 ttatttttta aatagtattc aaattcactt tgttttttaa ttttat
//
LOCUS       DAMJXI010000158         2882 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.168, whole genome shotgun sequence.
ACCESSION   DAMJXI010000158 DAMJXI010000000
VERSION     DAMJXI010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2882
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.168"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            295..1218
                     /locus_tag="PC465_003749"
     CDS             295..1218
                     /locus_tag="PC465_003749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HDF2651011.1"
                     /translation="MGSGKVGTSLANYFLSKGYCVSGFYGRNQLSLLESTNLTKTKIY
                     SNLKDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSKKAG
                     ALIYSIHPIFAFSNKNTNIKKMKDICFSIESDNEQDDLVIQNFIDDLGNQFFIRDKDT
                     SATYHLANVLVSNLVLSLLDIGVSYFIKLGLSEEESLKAISPLVKKNIENILDNGFTK
                     ALTGPVSRGDITPIRKHLSVLDKKDEDIYKILSLNILKIIALGNDNSLKGIKNITIEN
                     AIENLISKSEKYKEIYKLLGGKNDEKYHTDF"
     gene            1193..2020
                     /gene="panB"
                     /locus_tag="PC465_003750"
     CDS             1193..2020
                     /gene="panB"
                     /locus_tag="PC465_003750"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HDF2651012.1"
                     /translation="MKNTIQTFKNAKYEGKKLSMLTAYDYSIAKIMDECDINGILIGD
                     SLGMVIKGEENTLSVTIDEIIYHTKAVKNGVKNALIVSDMPFLSYHVSIEDAVKNAGR
                     LIKEGGAHAVKLEGGSNVIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKVQGNTSET
                     ARQLIEDAKLIEKAGAFSIVLEGVPTKIAEMVTNSISIPTIGIGAGINCDGQILVYQD
                     MLGMFGDFVPKFVKQYANIGDIMKDSIKNYILEVNTGAFPQEKHSFSINESELEKLY"
     gene            2039..>2882
                     /locus_tag="PC465_003751"
     CDS             2039..>2882
                     /locus_tag="PC465_003751"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HDF2651013.1"
                     /translation="MLVKEIKLLRNIIKDWRKHGYSIGLVTTMGFLHEGHQSLIKKAI
                     KENDKVVVSVFVNPTQFGPNEDFNSYPRDIDKDFKYCMDSGATVVFNPSPEEMYLKGN
                     CTTINVSGLTDFLCGAKRPVHFGGVCLVVSKFLNIVTPDKAYFGEKDAQQLAVIKRMV
                     KDLNIDTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNKSLSLAKEELVKGNLN
                     PENIKELITAKINSEHLAKIDYVEIVDSETLQPVKQIEHSILVAIAVFIGKTRLIDNF
                     TFELN"
BASE COUNT         1150 a          339 c          461 g          932 t
ORIGIN      
        1 atcataattt ttctaataga cttaatcact tttaatatat atagtaaaac aaaaaactta
       61 tattttataa atatcataat ttttttactg atattttatt atataaattt tatagaatta
      121 attgtcaatt ttttatgaaa atggtaagat atttatggat ggtatcttgt tataagaact
      181 atactttaaa tgtttttaat tattttgtct tatgtaactc atatcctcag gaatgagatt
      241 agaaattaag atgttgtatc acaaagtgga ggtgatacta ttaaaatagg ctttattggt
      301 tctggaaaag ttggaacatc tttggcaaat tattttttat caaaaggtta ttgtgtttca
      361 ggcttttatg gaaggaatca attatcttta ttagaatcaa caaatttaac aaaaacaaag
      421 atttacagca atttgaaaga tataatttat gaaaacgata tattatttat tacaacatca
      481 gatgattcta ttgaaattat agacaaaaaa ctttccaaat ttaatttaaa acataaatac
      541 atttgccaca caagtggctc tttaaaatct agtatattgt tctgttcaaa aaaagcaggt
      601 gcattaattt attctatcca tcctatattt gcattttcca ataaaaatac caacataaaa
      661 aaaatgaaag acatttgttt ttccatagaa agtgataatg aacaagatga tttagttatt
      721 caaaatttca tagatgattt gggaaaccaa ttttttataa gagataagga tacttcagcc
      781 acttatcatt tagctaatgt tttagtttca aatttagtat tatctttact agatatagga
      841 gtaagttact ttattaaatt aggtttatct gaagaggaat ctttaaaagc tatcagtcct
      901 ttagtaaaaa aaaatataga aaatatactt gataatggct ttactaaagc tcttactggt
      961 cctgtttctc gtggagatat aacaccaata agaaaacatc tatctgtatt ggataaaaaa
     1021 gatgaggata tttacaaaat actatcctta aacatactaa aaataattgc cttaggaaat
     1081 gacaattcat taaaaggtat aaaaaatatt actatagaaa atgcaatcga aaatttaata
     1141 agtaaatctg aaaaatacaa agaaatttac aaacttttag gaggaaaaaa cgatgaaaaa
     1201 taccatacag acttttaaga atgctaaata tgaaggaaaa aaactatcta tgcttactgc
     1261 ttatgactac tcaattgcaa aaataatgga tgagtgtgat ataaatggta ttttaatagg
     1321 agattcatta ggaatggtta taaaaggtga agaaaacact ctatctgtta ccatagacga
     1381 aattatatat catacaaaag ctgtaaaaaa tggtgttaaa aatgccttaa tcgtaagtga
     1441 tatgcctttt ctatcttacc atgtttctat agaagatgca gttaaaaacg ccggtagact
     1501 tataaaagaa ggaggagctc atgctgtaaa gttagaaggt ggctcaaacg ttataaagca
     1561 aatagaaagc attgtaaatg ctcaaatacc tgtaatgggg catttaggat taactcctca
     1621 atcagtaaat tcatttggtg ggtttaaggt tcaaggaaat accagtgaaa cagcaagaca
     1681 acttattgaa gatgctaaat taatagaaaa agcaggtgca ttctctattg tccttgaagg
     1741 agtgcctacg aaaatagctg agatggtaac taattctatt tcaattccta caataggtat
     1801 aggggcagga attaactgtg atggacaaat tttagtttat caagatatgt tgggaatgtt
     1861 tggagatttt gttcctaagt ttgtaaagca gtatgcaaat ataggagata taatgaaaga
     1921 ttcaattaaa aattacatcc tagaagttaa tacaggtgca tttccacaag aaaaacacag
     1981 cttttcaata aatgaatctg agttagaaaa attatactaa tattaaggat ggtacaaaat
     2041 gcttgtaaaa gaaattaaat tactaagaaa tataatcaaa gattggagaa aacatggcta
     2101 ttctataggg cttgttacaa caatgggatt tttacatgaa ggacaccaaa gtcttataaa
     2161 aaaagctata aaagaaaatg ataaagtagt agtgagtgta tttgtaaatc caactcaatt
     2221 tggaccaaat gaagatttta atagctatcc aagagatata gataaagatt ttaaatattg
     2281 tatggatagt ggagcaacag tagtctttaa cccatcacca gaagaaatgt atttaaaagg
     2341 taattgtact accattaatg tttctggact tacagatttt ctttgtggag ctaaaagacc
     2401 tgttcatttt ggaggtgtct gcctagttgt ttcaaagttt ctaaatatag taacacctga
     2461 taaagcttat tttggagaga aggatgccca acaattagct gtaattaaaa gaatggtcaa
     2521 ggatttaaac atagatacag aaataatagg ctgtcctata attcgtgaaa atgatggatt
     2581 agcaaaaagt tcgagaaata catatctctc tgaggaagaa cgaaaatctg ctctaatatt
     2641 aaataagagc ttaagtttag caaaagaaga attagtaaaa ggcaatctaa atccagagaa
     2701 tataaaagaa ttaataacag ctaaaataaa ttctgaacac ttagcaaaaa tagactatgt
     2761 tgaaattgta gatagtgaga cattacaacc tgttaagcaa atagaacatt ctatacttgt
     2821 ggcaattgct gtgtttatag gaaaaaccag actaattgat aattttacat ttgagttaaa
     2881 ta
//
LOCUS       DAMJXI010000159         2877 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.169, whole genome shotgun sequence.
ACCESSION   DAMJXI010000159 DAMJXI010000000
VERSION     DAMJXI010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2877
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.169"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            70..2427
                     /locus_tag="PC465_003752"
     CDS             70..2427
                     /locus_tag="PC465_003752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HDF2651014.1"
                     /translation="MDKVNLERYSCDINVGLNKNQLQSRIDDNLINAFDNGKTKTYKQ
                     IFKDNIFTLFNLINIVLVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLS
                     VIVSNKVSVIREKEKKEIDVQELVLDDIMILKTGNQICADSKVLNGKLEVNESLVTGE
                     SDIIIKNKGDFLYSGSFVVSGEAFVRVENIGKDNYANKIANDAKISKKHNSQLRNSLN
                     AILKIVGIIIIPLGIILFAKQHFGNGDSIATSVVGTVAAVNGMIPEGLTLLTSIALAV
                     GTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDIVMLEEVDINEIMG
                     NICNSLKDDNATLNAIRDKYNVLDTYKAKNLIPFSSERKYSGVTFENKGTYLLGAFEF
                     IFKEKNKKLRIEVERYSKKGNRVIVLAHSDSYMEDNNIPEDIKPLAFILILDKIRDEA
                     KETLEFFYNEGVDIKIISGDNPITVSEVARKAGLKTASNFIDATTLKNDSDIYKAVDK
                     YSVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNV
                     SNLVLLDSNFASMPKVVMEGRKVINNIQRASSLFLVKTIFSFFLSLLTLFFFSRQYPF
                     VPIQLSLIGAVTVGIPSFFLALEANKSRISGNFLLNILKNALPGALCVTVNVIIVYNI
                     VEYLGYSSSVFSTMCAILTGVCGLLILRQQCLPFNKERLFLIVSMTIAFVIGILFLGG
                     LFSFVALSRELILITMVLAILMPIMIKVMLFVLDEILETIVPDLN"
     gene            complement(2513..2830)
                     /locus_tag="PC465_003753"
     CDS             complement(2513..2830)
                     /locus_tag="PC465_003753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HDF2651015.1"
                     /translation="MSEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEY
                     TFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSY
                     IAD"
BASE COUNT         1074 a          326 c          476 g         1001 t
ORIGIN      
        1 aaattgagaa ttttataata tatttgtaga tttgagtata aaaaagtgct aagttgaaag
       61 gagtaaaata tggataaggt taatttagaa aggtatagtt gtgatataaa tgttggttta
      121 aataaaaatc aacttcaaag tagaatagat gataatttaa ttaatgcatt tgataatgga
      181 aaaaccaaaa catataaaca aatttttaaa gacaatatat ttacactttt taatctcata
      241 aatattgttt tagtctgttt attagtttca gttggttctt ttaaaaatac cttatttata
      301 tttattgctg taattaatac tattatagga gtaatacaag agataagagc taaaagatta
      361 ttggacaatc tatctgttat agtttcaaat aaggtatctg tcataagaga aaaagagaaa
      421 aaagagattg atgtacaaga attagtatta gatgatatta tgattttaaa aacaggtaat
      481 caaatttgtg cagattcaaa agttttaaat ggaaaattag aggtaaatga gtccttggtt
      541 acaggtgaat ctgatattat tataaaaaat aaaggcgatt ttttatattc tggaagtttt
      601 gtagtttctg gagaagcttt tgtaagagtt gaaaatatag gaaaagataa ctatgcaaat
      661 aagatagcta atgatgcaaa gatttctaaa aaacataatt ctcaacttag aaattcatta
      721 aatgcaatat taaaaattgt aggtataata ataattcctc taggaattat attgtttgca
      781 aaacaacatt ttggaaatgg agattctata gctacatctg tagtaggtac agtggcagct
      841 gtaaatggta tgataccaga gggattaaca ttacttacga gcattgctct agctgtagga
      901 actataaaac ttgctagtca taaaacttta gtgcaagaac tgtactgtgt agagactctt
      961 gctagagttg atacactatg tcttgataag acaggtacaa ttacagaagg taaaatgcaa
     1021 gttgatgata tagtaatgtt ggaagaagtg gatattaatg aaataatggg gaatatatgt
     1081 aattctctca aagatgataa tgcaacacta aatgcaataa gagataagta taatgtttta
     1141 gatacgtata aagctaagaa tttaatacca ttttcttcag aaagaaaata cagtggggtt
     1201 acctttgaaa ataaaggtac atatttatta ggtgcatttg agtttatatt taaggaaaaa
     1261 aataaaaaac ttaggataga agttgaaaga tattctaaaa aaggaaacag agtaatagtt
     1321 ttagctcata gtgattctta tatggaagat aataatattc ctgaagatat aaagccacta
     1381 gcttttatat tgatattgga taaaattaga gatgaagcta aggaaacttt agaatttttt
     1441 tacaatgaag gtgtagatat aaaaattata tctggtgaca atcctataac agtaagtgag
     1501 gtagctagaa aagcaggtct taaaacagct agtaatttta ttgatgcaac aacacttaaa
     1561 aatgatagtg atatatacaa agcagttgat aaatacagtg tttttggaag ggtaagccca
     1621 caacagaaaa aacaaatgat tttagcatta aaaaaacaaa atcatacagt agctatgact
     1681 ggagatggtg taaatgatgt gctagcactt aaagaagcgg attgtagcat tgccatggca
     1741 tctgggagtg atgttactaa gaatgtgtct aatttagtct tattagattc aaactttgca
     1801 tcaatgccaa aggttgttat ggagggaaga aaagtaatta ataacattca aagagcatct
     1861 tctttgtttt tagtaaagac aattttttca ttcttcttgt cgttattaac attattcttc
     1921 ttcagtagac agtatccatt tgttcctata caattatcac tcattggggc tgtaacagtg
     1981 ggtataccat cattcttctt agctcttgaa gcaaacaaaa gtagaatttc aggaaatttt
     2041 ttactcaata tattaaaaaa tgctttacca ggagcactat gtgtgacagt aaatgtaatt
     2101 attgtttaca atatagttga atatttaggt tatagttcaa gtgtattttc cacaatgtgt
     2161 gctatattaa ctggtgtatg tggtctttta atattaagac aacaatgttt gccatttaat
     2221 aaagaaagat tatttttaat agtaagtatg actattgcat ttgttattgg gattctattt
     2281 ttaggtggat tattctcatt tgtagcattg agtagagaat taattctcat aactatggta
     2341 ttagcaatat taatgccaat tatgataaaa gttatgttat ttgtcttaga tgagatatta
     2401 gagacaattg ttccagattt aaattaattt taaaatgata taaataagag cagttttagt
     2461 tgaactgctc tttttagatg tgtttaattt tatgtaagaa tatgtatttt tattaatcag
     2521 ctatatatga gcaacagtag tcaacaactt cattaacctt taagtcaaaa cttgaatcac
     2581 taggaacatt aaatttttgc ccttctttat aagttacaaa ctcattgctt ccaggcagtt
     2641 ttacatccat acttccagca agcatctcca ttatttcttc ttctctagta gaaaaagtgt
     2701 attctcctgg caacattaat cctaaagttt ttctttctcc attaggcagt attattactc
     2761 tgctacttac cttaccatca aaataaacgt ttgccttctt tactgcagta acattcttaa
     2821 attcactcat tagataaaac ctccaaaatt atttgtacat atatattata taaaaat
//
LOCUS       DAMJXI010000160         2731 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.170, whole genome shotgun sequence.
ACCESSION   DAMJXI010000160 DAMJXI010000000
VERSION     DAMJXI010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2731
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.170"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(798..1835)
                     /locus_tag="PC465_003754"
     CDS             complement(798..1835)
                     /locus_tag="PC465_003754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2651016.1"
                     /translation="MIKSKKILSLIIAGVLGVSMLTGCSQNDGSNASNENKETDSKKQ
                     KNIGISQLVEHPSLDKAKKGFIKALEDKGYKDGDNIKIDFQNAQNDMPTTQSIASKFV
                     SDKKDLIYAISTPSAQAAYNSTKDIPIIMTAVTDPVEAGLVKSLEKPGGNVSGTSDYL
                     SIDKTLELVKTLTPKAKKIGVIYNTSEVNSKIQVDSLHDYAKKNNYEVFEKGISSSSE
                     VNQAISSLVGKIDVLYVPTDNLIVSSMPIVSKVANENKIPIIASEEGSVSSGALACCG
                     IDYEKLGYKAGELAIEVLEGKSVGDIPVTTLDETEIIINEDTLKALDMQKLSADNIKY
                     IKSDENAKSAK"
     gene            complement(1932..2687)
                     /locus_tag="PC465_003755"
     CDS             complement(1932..2687)
                     /locus_tag="PC465_003755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003399531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2651017.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQITLDSTTITNLAEYKRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLKKCLRHKTNDLEHLLEGISLDLKKYLDIKVQYLSGGQRQSLSLIM
                     SSLASPKVLLLDEHTAALDPKTSNEVIELTDKIVREKNITTLMVTHNLKHALQYGDRL
                     IMLHKGEVVLDVKDKEKEDLTVEEILEKFEYAV"
BASE COUNT          897 a          407 c          348 g         1079 t
ORIGIN      
        1 cctttgaaaa tatttttata attttaatta tttgctaatt ttgtgtataa aaaaaccaca
       61 tagtgtacaa aactatgtgg taaaaacacg aataagccac atagtttaat ctatgtggct
      121 cttatatagt taaatgaaaa ctttataaac aatatagcca acatagatac aatcccaaaa
      181 ttttagtagt cttaaggggt ctgtatctat gttaaaacgt aggtacaaac cctaaaaata
      241 gtggctataa taataataat attttctatt gtttaataaa gtattcataa ttatctctcc
      301 cttttaatat tttaattagt cagaaaatta tatgtattct cgacttgtta taaattataa
      361 attatacaat aataaaagtc aactgctaaa tttaattaaa atactaaata atgtatactc
      421 agaatacttt taaattaatg tattgtttgc aaaaaaacgt tatcctaagt tataagtgaa
      481 tgtggaaatt ttatcaaaat atttactaaa tatggaataa ctagacatgt atatcaatca
      541 aatatcataa aaaaaagctg tctggagaat attaaaattc ttttggacag ctcaagtagt
      601 gattagaaag ttatataact ttcataatca gtcgtcaata tagacgactt ttatggaaaa
      661 tgaataactt tatatgcaat attcaaattg ctacaataag cacaattttc aaagggttag
      721 ggtggataag agtacttatt atataaagtt ttcatattac ctacttcata ttacctattt
      781 tttgaaatta ataggtttta ttttgcagat tttgcatttt catctgactt tatatacttt
      841 atattatctg ctgataactt ttgcatgtca agtgctttta gtgtatcttc gttaattatt
      901 atttcagttt catctaatgt agtaactggt atatcgccaa cagattttcc ttctaatact
      961 tcaatagcaa gttctccagc cttataacct agtttttcat aatctattcc acaacaagct
     1021 aaagcaccag aagatacaga accttcttca gaggctatta taggaatctt gttttcatta
     1081 gcaactttag aaactattgg catagaagaa actattaaat tgtcagtagg gacatataaa
     1141 acatctattt tgccaactaa actagaaata gcttggttaa cttcacttga agagctgatt
     1201 cctttttcaa atacttcata attatttttc ttagcataat catgtagaga atcaacttgg
     1261 atttttgaat taacttcact agtattgtat ataaccccta ttttctttgc ttttggagtc
     1321 aatgttttaa ccaattctaa tgttttatca attgaaagat aatcagatgt accagaaaca
     1381 tttccacctg gtttttcaag agatttaaca agtccagctt ctacagggtc tgtaacagca
     1441 gtcattatta tcggaatatc tttagtagaa ttataagctg cttgtgcaga tggagtagat
     1501 atagcatata tcaaatcttt tttgtcggat acaaacttac tagcaatact ttgtgtagta
     1561 ggcatatcat tttgtgcatt ttggaaatct atttttatat tatctccatc tttatagcct
     1621 ttatcttcga gtgctttgat gaatcctttc tttgctttat ccagagatgg atgttccact
     1681 aattgactaa tacctatatt tttttgtttt ttgctatctg tttctttatt ttcatttgaa
     1741 gcattggagc catcattttg agaacatcca gtaagcattg atacaccaag tactcctgct
     1801 ataattaaac ttaatatttt tttacttttt atcattttat tttcctccct taaaatttat
     1861 taattatatt tgttcatata ttcatatgat agattataaa tatttctgat taaaactaag
     1921 attttaattt cttatactgc atattcaaat ttttctaaga tttcttcaac tgttaaatct
     1981 tctttttctt tatcttttac atctaataca acttcaccct tatgaagcat tatcaaccta
     2041 tctccatatt gaagagcgtg tttcaagttg tgagtaacca taagtgtagt tatatttttt
     2101 tctcttacga ttttatctgt taactctatt acttcatttg atgtttttgg gtcaagtgct
     2161 gctgtatgtt cgtctagtaa taagacctta ggacttgcta agctagacat aattagtgat
     2221 agtgattgtc tttgacctcc tgaaagatat tgtactttaa tatctaaata tttttttaaa
     2281 tccaaagaaa ttccttcaag taagtgttcc aagtcattcg ttttatgacg aagacatttt
     2341 tttaagttca ataatttccc tttattaagt gctagagata aattttctct aaccgtcata
     2401 gaaggacaag ttccaaggct tgggtcttga aaaactctac ttactatttg agttctttta
     2461 tactcagcta aatttgttat agtagtacta tctaaagtaa tttgaccaga agattctttt
     2521 ataagcccag atattatatt taataaagta gatttaccag ttccattact acctatgata
     2581 cttacaaatt caccatcttc tatatcgatt gataaatttt caaagatagt attaggttca
     2641 ccatatggat tagggaaact ctttgaaaga tttttaattt gtaacatcta caacacctct
     2701 tttttctgat ttatttttgg tactagcttt g
//
LOCUS       DAMJXI010000161         2717 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.171, whole genome shotgun sequence.
ACCESSION   DAMJXI010000161 DAMJXI010000000
VERSION     DAMJXI010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2717
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.171"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            373..2184
                     /locus_tag="PC465_003756"
     CDS             373..2184
                     /locus_tag="PC465_003756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF2651018.1"
                     /translation="MKKKYDFLIYSAIWLVIIILFIFSLYHSIEHIKIISHTGTIRSE
                     TQKVVKQELNNERNDDLIKRLDNILIKLRTGNGENGFQRCDNKEFQQKLNQMDSMWES
                     MKKEIIKVRNGASGDKLYKLSEEYSVLSNQIVFISEKHSNAKLYSFATALFIYLIFST
                     ISLLIWEYYNKKRFKRIFYTDNLTKIKNQVAFENRAIEILHNASNKEYVLLNIDIDNF
                     KYINDTHGYEYGDKVLIIVAAVLSKTFNIKETCARIGSDNFVILAKYRDSLLEDIREM
                     LTNAIISELDMNVTQTISYCIGAYLVEIDNLGYKSINSIMDKANIAHKVSKTRGISST
                     VWYNENLLKQLQIENSIYNYMYKAIENEEFHMYLQPKFQISSLNVVSAEALVRWFSPE
                     LGFLSPDEFIPLFEKSGFIIELDFYMLKKACSFVRKTFMKKNQYTYPIAVNFSRVTIY
                     QNSFYQRFLDTVKEYEIPFKYIEIEVTESAFNEISQPVISILEELKKLGFLISMDDFG
                     SGYSSLSLLCSLSINGLKLDKSLLKETFNREKVYSIIQCIIEMSHRIGMSVVCEGIET
                     KKDLEFLNTVKCDVGQGFYFSKPIEEKEFFNKYVTKK"
     gene            complement(2272..2502)
                     /locus_tag="PC465_003757"
     CDS             complement(2272..2502)
                     /locus_tag="PC465_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003171502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651019.1"
                     /translation="MKDYIQKRESLYIETKKYYEEKGLKIERHALGSEDGEYVELTNY
                     SILYLLDIEAVEIREQSKNIEEFLYKYKKRFK"
BASE COUNT         1027 a          278 c          401 g         1011 t
ORIGIN      
        1 aaattgtagg taaatagtat tttaattatt tattaaaata tagattatgt atatgccaaa
       61 tttaaaaaga gacataaaga cattatacaa atatattatt ggggtgatat tttataagaa
      121 aagaagtgat gcagtaaatt aattgagcaa tttaaaaatg atttaatgat agtgttgatg
      181 aatgtttaaa aagaaatttt agaaaaacgt atattgctgt ttgtgttgga ggtgatgaat
      241 ttgtataatt tataggatat aaatgattaa actatttaag ataaatacat atcactgtaa
      301 aatattgata atcatttttt ataagagatt gattatttgc aaattatata tattacaaat
      361 gaggtaacaa taatgaagaa aaaatatgat tttttaattt attctgctat ttggctagtt
      421 attattattc tttttatatt ttctctatat catagtatag agcatattaa aattataagt
      481 cacactggta ctattcgcag tgaaactcaa aaggttgtta agcaagaatt gaataatgaa
      541 agaaatgatg acttgataaa acgactggat aatattctga taaagctaag aacaggtaat
      601 ggagaaaatg gatttcaaag atgtgataat aaagaatttc aacaaaaact aaatcaaatg
      661 gattctatgt gggaatctat gaagaaagaa attataaaag ttagaaatgg tgcttcaggt
      721 gataaattat ataaattgag tgaagagtat tctgtgttgt ctaatcaaat tgtttttata
      781 tctgaaaaac actctaatgc aaaattgtat tcttttgcta ctgcactatt tatttatctt
      841 atattctcaa caataagtct tttaatttgg gaatattata ataaaaaaag gtttaaaaga
      901 atattttata ctgataattt aacaaaaata aaaaatcagg ttgcatttga aaacagagcg
      961 attgaaattt tgcacaatgc atctaacaaa gagtatgtac tgctaaatat tgatattgac
     1021 aattttaaat atattaatga tacacatgga tatgaatatg gagataaagt tctaataata
     1081 gttgcagctg tactttctaa aacttttaat atcaaagaaa cttgtgcaag aattggttca
     1141 gataattttg taatacttgc aaaatataga gattctcttt tagaggatat tcgggaaatg
     1201 ctaactaatg ctataatctc tgaattagat atgaatgtaa ctcaaactat atcttattgt
     1261 ataggagcgt acttagttga aattgataat ttaggttata aatccatcaa ttctataatg
     1321 gataaggcaa atattgcaca caaggtaagt aaaacaagag gaatttcctc cacagtatgg
     1381 tataatgaaa atctgttaaa acagttacaa atagaaaata gtatttataa ttatatgtat
     1441 aaagcgatag aaaatgaaga atttcatatg tatttgcaac ctaaatttca aatatcttct
     1501 ttaaatgttg tgagcgcaga agctcttgta agatggtttt ctccagaact tggtttttta
     1561 tcaccagatg aatttattcc attgtttgaa aaaagtggat ttattattga attggacttt
     1621 tatatgttaa aaaaagcgtg ttcatttgta agaaaaacgt ttatgaaaaa aaatcaatat
     1681 acatatccga ttgcagttaa tttttcaagg gttactattt accaaaatag tttttatcaa
     1741 aggtttttag atactgttaa agaatatgaa attcctttta agtatataga gatagaggta
     1801 actgaaagtg cttttaatga aatatctcaa ccagttattt cgattttaga ggagcttaaa
     1861 aagttaggat ttttaatttc aatggatgat tttggatcag gatactcttc attaagtctt
     1921 ttatgttctc tatctattaa tggattgaag ttagataaaa gcttacttaa agaaacattt
     1981 aaccgggaga aagtatatag tattattcag tgtattattg aaatgtcaca tcgtataggc
     2041 atgtctgttg tatgtgaagg tattgaaact aaaaaagact tggaattttt aaatacagtt
     2101 aaatgtgatg taggacaagg gttttatttt tctaaaccga tagaagaaaa agaatttttt
     2161 aacaaatatg taactaaaaa ataatataat tatttttatc agtctataca ttgagtcatt
     2221 ttatatctcg ttaaatgact caatgtattg ttatgtattt taaaatataa attatttaaa
     2281 acgttttttg tacttatata gaaattcttc tatatttttt gattgttctc ttatttcaac
     2341 tgcttctata tctagtaaat aaagtataga ataatttgta agttcaacat attcaccatc
     2401 ttctgaaccg agtgcatgtc tctcaatttt taatcctttt tcttcataat atttttttgt
     2461 ttctatatat agtgattctc gcttttgtat gtagtctttc acttcattat ttggaaagtt
     2521 atatgaatcc actaatgttt cgccatttat aaaagttttc tcggtagcaa ctttttcatc
     2581 ccaacaatgg atttcttccc aagtaaaaaa tatctcagtt ccatctggaa tgaatgaaaa
     2641 cctggtaata atatataaat aattattgaa atttacttca taatattcag gaatatcttc
     2701 aaattccata tagtaat
//
LOCUS       DAMJXI010000162         2708 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.172, whole genome shotgun sequence.
ACCESSION   DAMJXI010000162 DAMJXI010000000
VERSION     DAMJXI010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2708
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.172"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            200..1798
                     /locus_tag="PC465_003758"
     CDS             200..1798
                     /locus_tag="PC465_003758"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HDF2651020.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPEILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDIKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VVSVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEIMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYQMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDIDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLILSVTDIIKEGSYLIYKAEDSLIANAFGVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
     gene            complement(2033..>2708)
                     /locus_tag="PC465_003759"
     CDS             complement(2033..>2708)
                     /locus_tag="PC465_003759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HDF2651021.1"
                     /translation="GATGPTGNTGVTGEIGPTGATGPTGNTGVTGEIGLTGATGPTGN
                     TGATGSIGPTGVTGPTGATGVTGPTGPTGATGNSSQPVANFLVNAPSPQTLNNGDAIT
                     GWQTIIGNSSSITVDANGTFTVQENGVYYISVSVALQPGSSSINQYSFAILFPILGGK
                     DLAGLTTEPGGGGVLSGYFAGFLFGGTTFTINNFSSTTVGIRNGQSAGTAATLTIFRI
                     ADTVMT"
BASE COUNT          937 a          396 c          419 g          956 t
ORIGIN      
        1 atttaattcg atatttgatt gggtaaaagt atatataata ataattttta tattaaattt
       61 gtagtattta tgtaagaaat aaattttata taatattttt tcactaaatt tttttctttt
      121 tacaacaaat actcactacc ttttgatata atatttttat caattattat tatattcaag
      181 ttttgaaagg agtattaaaa tgagtttatt agttttcgga cataaaaatc cagatacaga
      241 ttcaatatgt tctgcaattt cattagcaca tttaaagaac aaactaggaa taaaagcaac
      301 agcttatgct ttaggagata tcagaaaaga agctaaatat gccttggatt actttaaggt
      361 agatgcacct gaaattttag ataatgttag aatacaagtt agagatttaa attatgataa
      421 agtagtacct ttaacaccaa cttcatctat attagaggcc tataacctta tggatgaaaa
      481 aaatgttaaa acactacctg taacttatga tgatggaact tttgctggta tcattactat
      541 gaaagaaata gctaaaaatc tacttcatca acactttaca actatacaca catcactatc
      601 aaacatttgt aaaaacctta atggtactat tcttgtggac tgtggtgaag atataaaagg
      661 tagagtagtc actttatcat ttggaatgga gactctaata gagactttaa aagaaggaga
      721 catagctatt gttggagata gatatgatag tattgaatat gctattgata caaaagttaa
      781 acttttaata cttactaatc atacagagat ttcaaaagat ttgctagctc ttgctaagat
      841 aaatggagtg tctgttgttt ctgttgaaag tgacaattat aaaacttcta atgtaataaa
      901 tcaatgtagt ttcttagact ctatagaagc tacagaaaat ttaattacat tcaaagaaga
      961 tgattatatg gatgaaataa aagagattat gctagaaaca aacttcagat cttatccaat
     1021 attagatgat gataataagt ttttaggttt agtttcaaaa ggtcatctat taaacccatc
     1081 taaaaagaat gttgttttag ttgaccataa cgaatatgct caaagtgctg atggaattga
     1141 acaagcaaac atagttgaaa taattgacca tcataaactt ggtggtattt ctactgatgt
     1201 tcctatgtca tttagagtta tgcctgttgg atgcaatagt actataattt atcaaatgta
     1261 caaagaaaat aatgttgaga taccttatga aatagccggg cttcttttat ctgctatatt
     1321 atcagataca ttattattta agtctccaac aacaactgat atagataaga aagcttgtga
     1381 agaattaagt aaaatagcaa aagtagacat ggaaaaatac gctatggata tgtttaaatg
     1441 cggtacttct ttagatgaat atactataga agaaatagta aatatggact ttaaagaatt
     1501 taatatgagt ggacatagag ttggtattgg acaagtattt accttagaca tagactctat
     1561 atttgctaaa aaagatgagt ttttatctta tataaattcg actgattatg ataaattaat
     1621 tctttcagtt acagatataa tcaaagaagg ttcttattta atctataaag cagaagatag
     1681 cttaattgct aacgcatttg gtgttgaagg tgttcaaggc acatttgcac caggtgttgt
     1741 atcaagaaaa aaacaattag tccctaattt aactactgca atcaaaaatt ttaaataata
     1801 taaaattttt aaataacgaa aactgtctca aatctatatt tgagacagtt ttttattata
     1861 tatatattga taataaagtt aaataaaaat ccataaattt aaaattttta tgaatatatt
     1921 ttattattat tgttatttta ttcattctaa aataggtaaa actcaatata taaaaatact
     1981 tttgtcattt aaataaagcc taaatagttt ttaagattat tttagacacg ttttaagtca
     2041 taacagtatc agctattcta aatatcgtca aagtagccgc agttcctgct gattgcccat
     2101 ttcgtatccc tactgttgta gatgaaaaat tatttattgt aaaagtagtc ccaccaaata
     2161 aaaaaccagc aaaatatcca gaaagtactc ctccgcctcc tggctcagta gtaagccctg
     2221 ccaaatcttt tcctcctaaa attgggaata ggatagcgaa agaatattga tttatacttg
     2281 atgaacctgg ttgtaatgct actgaaactg atatataata cacaccattt tcttgtactg
     2341 taaacgtacc atttgcatct actgttatac ttgaactatt tcctattatt gtttgccaac
     2401 ctgttatagc atctccatta tttagtgttt gtggagatgg tgcatttacg aggaagttag
     2461 caactggctg agaggaattg cctgttgctc ctgttggacc tgttgggcct gttactcctg
     2521 tcgctcctgt tggtcctgtt actcccgttg gccctatact tcctgtcgct cctgtatttc
     2581 ctgttgggcc tgttgctccc gttagtccta tttctcctgt cactcctgta tttcctgtcg
     2641 gacccgttgc tcccgttggt cctatttctc ctgttactcc tgtatttcct gttgggcctg
     2701 ttgctccc
//
LOCUS       DAMJXI010000163         2591 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.173, whole genome shotgun sequence.
ACCESSION   DAMJXI010000163 DAMJXI010000000
VERSION     DAMJXI010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2591
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.173"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            <1..372
                     /locus_tag="PC465_003760"
     CDS             <1..372
                     /locus_tag="PC465_003760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4368 domain-containing protein"
                     /protein_id="HDF2651022.1"
                     /translation="LKKAENRQNEIDRLFAKMYEDRACEKITERNFIMLSGKYQKEQI
                     ELEQQITNLREELSKMEQDMIGAERWIELIKEYSVPKELTAPLLNAMIEKILIHEATT
                     NEENERIQEIEIYYRFIGKVD"
     gene            401..724
                     /locus_tag="PC465_003761"
                     /pseudo
     CDS             401..724
                     /locus_tag="PC465_003761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861830.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
     gene            756..1943
                     /locus_tag="PC465_003762"
     CDS             756..1943
                     /locus_tag="PC465_003762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HDF2651023.1"
                     /translation="MSKIVFFSIPAYGHTNPTIEVVRELVDRGNEVLYYSFNEFKDKI
                     EGAGAKFICCDKYLPELLPGDEKKIGKDFPGLIEMIVDTTISLDEKVCRELKDFNPDC
                     IVSDSLSFWGKLFAQKLNIPYVCSTTTFAFNKHTAKLMKQNFIEIIRMIFGVRRINKK
                     IKLLQRKGYEVKNFISIVSNDNDTDTIVYTSKEFQPMVETFSSKYSFVGPSVSKLIIE
                     PKERKRKLIYISLGTINNKNVSFYKNCINAFKDSDVDVIMSVGRSTNIKSLGNIPNNF
                     EVKNSVEQIAILQKTDVFVTHSGMNSVNESLYYGVPMVLFPQHSEQRMVAKRVVHLGT
                     GIMLKEDKSESIKKAVFQVINDNEYKENATKLSKSFYNAGGSKKAADVILQIICNSRQ
                     VDI"
     gene            2135..2539
                     /locus_tag="PC465_003763"
     CDS             2135..2539
                     /locus_tag="PC465_003763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HDF2651024.1"
                     /translation="MKKYKVIFIVLIIGIISVTGFVVYKNYIKPWKDAETYIDKYMVK
                     QDISKDNIKSITKEKAKKASYEGILYKVYYKGDPRYEYQYFYSDNYYALYVNKVMLQI
                     YDMENNNKLLRSNEELKSVKYPPIYLKYKPDK"
BASE COUNT         1044 a          264 c          481 g          802 t
ORIGIN      
        1 ttgaagaaag ccgagaaccg acaaaatgag attgaccgct tgtttgcgaa aatgtacgaa
       61 gatagagcct gtgagaagat aacggaacga aacttcatca tgctgtcggg gaaatatcag
      121 aaagaacaga tagaactgga acagcagata accaacctaa gagaagaatt aagtaaaatg
      181 gaacaggata tgataggtgc tgaaaggtgg attgagttaa tcaaggagta ttccgtacca
      241 aaggaactga cagcaccgtt attaaatgca atgatagaaa aaatccttat tcacgaagca
      301 acaacgaatg aggagaacga aagaatacag gaaatagaga tatattaccg atttattgga
      361 aaagtagact gataaagagg gttcatatct ttaactaagg gaaactggag aatctattcc
      421 tgatataggt agttgcatta aacttgcaaa attgtacaat gtcaaactag atgacttagt
      481 taatcattca gaagaaaaaa caggtattat agtacctcct aaaggaaagt ttttctttgg
      541 agcagttgta gttggtgaac gtggtcagat tgtcattcca aaagaagcaa gagaagtatt
      601 taatataaat gcaggagata aattattggt acttggagat gaggaaagag gattaggaat
      661 tgttcatcaa cgtgatttga taaattttat aggtcatgtg ggagtagtac gtaaagaaga
      721 atgatttaaa aaaattataa aaggaggtat gaaatatgag taaaatagta ttttttagca
      781 ttcctgcata tggtcatact aatcctacta ttgaagtagt tcgtgaatta gtggatagag
      841 gaaatgaggt attgtattat tcttttaatg aatttaaaga taaaattgaa ggtgctggag
      901 caaaatttat ttgttgtgat aaataccttc cagaattact ccctggagat gagaaaaaaa
      961 ttggtaagga ttttcctgga ttaattgaga tgatagtaga tactactatt tctttagatg
     1021 aaaaagtttg tagagaactt aaagatttta atccagattg cattgtatca gattcattaa
     1081 gtttttgggg aaagttattt gcacaaaaac ttaatattcc atatgtatgc tctacaacaa
     1141 cttttgcatt taataaacat acagcaaagt tgatgaaaca aaactttata gaaattatac
     1201 gtatgatttt tggtgtaaga cgcattaata aaaaaataaa gcttttacaa agaaaagggt
     1261 atgaagtaaa aaattttatt tctatagttt ctaatgataa tgatacggat accattgtat
     1321 atacatcaaa agaatttcaa ccaatggtag aaaccttctc tagtaagtat tcatttgtag
     1381 gtccatcagt atcaaagttg attattgaac ctaaagagag aaaaagaaag ctaatatata
     1441 tttcgcttgg tacaattaat aataaaaatg ttagctttta taaaaactgt ataaatgcat
     1501 ttaaagattc tgatgttgat gtgattatgt ctgttggtag aagtactaat attaaaagtt
     1561 taggaaatat accaaataat tttgaggtta aaaatagtgt tgaacagatt gctatacttc
     1621 aaaaaactga tgtgtttgtt actcattctg ggatgaatag tgttaatgaa agtttatatt
     1681 atggagtacc tatggtatta tttcctcaac attcggagca gagaatggta gctaagagag
     1741 ttgttcattt gggaacagga attatgttaa aagaggataa gtcagaaagt attaaaaaag
     1801 cagtatttca agttataaat gacaatgaat ataaagaaaa tgcaactaaa ctatcaaaaa
     1861 gcttttataa tgcaggaggc tcaaaaaaag cagcagatgt aatattacag attatatgta
     1921 atagtagaca agttgacata taatagattt gttaaaaata tatatacata catgtaattt
     1981 aatcaaagta ctgacagtgg ggtcttttaa cctaccagtt ggggcatata tattgatgct
     2041 aaatatgagg gatgttatat tttaataaaa aagataacat ccttttttta gtgcattata
     2101 tcgagtttta aataataaat gaaggaggat taatatgaaa aaatataaag ttatttttat
     2161 agtattaatt ataggtatta taagtgtaac agggtttgtt gtatataaaa actacattaa
     2221 accatggaaa gatgctgaaa catatattga taagtatatg gtaaagcaag atatttcaaa
     2281 agataatata aaaagtatta caaaagaaaa agccaagaag gcaagttacg aaggaatact
     2341 atacaaagtg tattacaaag gtgaccctcg atatgagtat caatattttt atagtgataa
     2401 ttattatgct ctatatgtaa ataaagtaat gttacaaatt tatgatatgg aaaataataa
     2461 taaactttta agaagtaatg aggaattaaa aagtgtaaag tatccaccaa tatatcttaa
     2521 atataagcca gataaatgat ttatgacaaa atagaatgat ttttattaaa atttatttaa
     2581 aaatatcact a
//
LOCUS       DAMJXI010000164         2512 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.174, whole genome shotgun sequence.
ACCESSION   DAMJXI010000164 DAMJXI010000000
VERSION     DAMJXI010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2512
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.174"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            381..2276
                     /locus_tag="PC465_003764"
     CDS             381..2276
                     /locus_tag="PC465_003764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp8"
                     /protein_id="HDF2651025.1"
                     /translation="MLSNKKRSMAIVMAGATVMSAAAPIFADNTVTENVDKNYTVSAK
                     DSAKLIEEVRKALEVKFEDTKAGANVNDRVYDIKVDNVNLTNATQLQNKINSLTEGQS
                     LKVTIQDKGHQVLGGKVVDYKIENYKTAQEIVDAVNAYNATLAEDSDNKLTATIKSTN
                     TVEVKRAKDSANVITLNVGDQHLDFSKVITSEEGTFEGYEKSYSDIDSKELHTITVKN
                     ADLQDISAEELFDGIRLTTLGREIVNKVKNGYALTFENEAILTQEQEDSDDKDKPEKS
                     SFDIVLSKANEKPETISVSSKNHKLVRDLHKVLTDVKGGKELKVEVLSGDSRFTTAVE
                     VSKERFKDGEAEAIILVGEDAIVDGLASAPLASQKNAPILLSKKDSLPSEIEAEILRV
                     LGSNLSSKKIYIVGGESKVSKETEEKLSKLGLSKVERVSGEDRFETSLEIAKQLKDTF
                     KTAFVVGGNGEADAMSISARAAQFGAPIIVTGNELDANAEKLLKGKELEIVGGENSVS
                     KEVEDKLVDIDLNNKVERLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVD
                     ALTAAPLAASSKAPIVLTTEELSKSQEEVVELRLKNATKLVQIGEGIAKNAIEKIAEK
                     INLFTKN"
BASE COUNT         1094 a          247 c          454 g          717 t
ORIGIN      
        1 aactctaatt tatgatgatt tttataatat gttatatatt ttaatatatg gagatagata
       61 ttaatttagt gatatatatt taagtaataa gagtaaagca aaaattagtg catagtagta
      121 tataaaaatg gagtttgaat acttttgtta gtatatgatt gtttagtaga aaatcactat
      181 aaaataggga tttctatctt tgagcataat tatagagagc taagtagggg gaaggggttc
      241 aagaagatat tattagtgtt tgtgttagta aattatgtaa acacataaaa tatattgaaa
      301 aataatatta tatataatat tatttatgtg tgggaaatac gaatataaaa aataaaaaat
      361 aatattcgga ggacataaat atgttaagca acaaaaagag aagtatggca atagtaatgg
      421 caggtgctac agttatgagt gcagcagcac caatattcgc agacaatact gtgacagaaa
      481 atgttgataa aaattacaca gtaagtgcga aagattctgc taaactaatc gaagaggtta
      541 gaaaagcatt agaagttaag tttgaagata caaaagcagg agcaaatgta aatgatagag
      601 tttacgatat aaaagtagac aatgtaaact taactaatgc aactcaatta caaaataaga
      661 taaactcttt aacagaaggg caaagtttaa aagttactat tcaagataaa ggacatcaag
      721 tgttaggtgg aaaagtagtt gactataaaa ttgaaaacta caaaactgct caagaaatag
      781 tagatgcagt taatgcttac aatgcaactt tagcagaaga ttctgataac aagttaacag
      841 caactataaa atctacaaat acagttgaag taaaaagagc aaaagattca gcaaatgtta
      901 ttacattaaa tgtaggagac caacatttag atttctcaaa agtgataaca tcagaagaag
      961 gtacttttga aggttatgaa aagagttata gtgacataga ttcaaaagaa ttacatacga
     1021 taacagttaa aaacgcagat ttacaagaca tatcagcaga agaattattt gatggaatta
     1081 gattaactac attaggaaga gaaatagtta ataaagttaa aaatggatat gctttaacat
     1141 ttgaaaatga agcaatcctt actcaagaac aagaagatag tgatgataaa gataaaccag
     1201 aaaaatcaag ctttgatata gttttaagca aggcaaatga aaagccagaa acaataagtg
     1261 tttcaagtaa aaaccataag ttagttagag acttacacaa agtattaact gatgtaaaag
     1321 gtggaaaaga attaaaagta gaagttttat ctggtgattc aagatttaca acagcagtag
     1381 aagttagtaa agagagattc aaagatggag aagcagaagc tataatttta gttggagaag
     1441 atgctatagt tgatggatta gcatcagcac cacttgcctc tcaaaaaaat gcaccaatat
     1501 tattatctaa aaaagattca ctaccatcag aaatagaagc tgaaatatta agagtacttg
     1561 gaagtaatct atcttctaag aaaatatata tagtaggtgg agaatctaaa gtatcaaaag
     1621 aaactgaaga aaaactttct aaattaggtt taagtaaagt tgagagagtt tctggagaag
     1681 atagatttga aacttcttta gaaatagcaa aacaattaaa agatacattt aagactgctt
     1741 ttgtagtagg tggaaatgga gaagctgatg ctatgagtat atcagctaga gctgctcaat
     1801 ttggtgctcc aataatagtt acaggtaacg aattagatgc aaatgctgaa aaattattaa
     1861 aaggaaaaga attagaaata gtgggtggag aaaattctgt atcaaaagaa gttgaagaca
     1921 aattagttga tatagattta aataataaag ttgaaagatt agctggagaa aatagaaaag
     1981 atactaatgc taaagtaatc aataaatact atgcaggtgc aactaaagca tatgtagcaa
     2041 aagatggtta tgtaggtgga aatggacaat tagttgatgc acttacagca gcaccacttg
     2101 cagctagttc aaaggctcca atagtattaa ctacagaaga actttctaaa tcacaagaag
     2161 aagtagttga gttaagactt aagaatgcta ctaagttagt acaaataggt gaaggaatag
     2221 ctaaaaacgc tattgaaaaa atagcagaaa aaataaactt atttactaag aactaataag
     2281 atataggaat taatattaaa agtttattta gataatatat gattatacaa tgcgttaata
     2341 tgtaagacat agtgtagata ttataaaata tacaaataac aagataaaat aataaaaata
     2401 aggtgtctca tttagaatta gattgagata ccttatttta ttttttgatt ataatgttga
     2461 gaaattcata ttgcaaaaat tattataaaa agatacttct tataatgatt aa
//
LOCUS       DAMJXI010000165         2424 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.175, whole genome shotgun sequence.
ACCESSION   DAMJXI010000165 DAMJXI010000000
VERSION     DAMJXI010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2424
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.175"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(144..1436)
                     /gene="brnQ"
                     /locus_tag="PC465_003765"
     CDS             complement(144..1436)
                     /gene="brnQ"
                     /locus_tag="PC465_003765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDF2651026.1"
                     /translation="MGEKQINFKDVIVIGFALFAMFFGAGNLIFPPYLGVLSGSSWLV
                     AFIGFLFADGGLALLAVIAATKFNGDTSKMFSRAGKGLSIALGCAMVICIGPLLAIPR
                     TAATTYEMGILPTIGSGISPVIFSIVFFALVLVLTIRPSKVVDIVGSILTPALLIALA
                     VLIVKGIVSPLGEIRDSSLIQNVFAEGITQGYQTMDALAASVFASIIIMSVIAKGYTG
                     EKEKMKATISAGVIAVIGMALVYGGLCYLGATVSQQYGQDVQQTALIVAITAALLGTT
                     GKILLAIIVALACLTTAIGLSSAAGQYFSTLTDGKLKYEHIVIVVCVFSAIISNFGVS
                     TIIQFSSPILSMVYPATITLVILALFSNKIKNNNVFKCAAYMALLVSVLTVATSFGVK
                     IPLVNSLPFASLGFNWIVPVVIAGIIGNFIPSKSSKTA"
BASE COUNT          816 a          389 c          252 g          967 t
ORIGIN      
        1 ctccaaaaat aaatttttaa atttatcaaa taggattaat aatgttcttt tatctacaat
       61 aatttaataa ttcttttaaa tataaaaagg aattgcctat ataatttaaa ggcaattcca
      121 taattatcaa ttagttttta ttattatgca gttttactgc ttttagatgg aataaagttt
      181 cctattattc ctgctattac aactggaact atccagttaa atcctaatga agcaaatggt
      241 aagctattaa ctagaggaat ttttacacca aaacttgttg caactgttaa tacacttact
      301 aataatgcca tgtatgcagc acatttgaac acgttgttat ttttaatttt attactaaat
      361 aatgctagta taactagagt tatagttgct ggatatacca tacttagtat aggagaagag
      421 aattgtatta ttgtacttac tccaaagttt gatatgattg cactaaatac acaaactact
      481 ataactatat gctcatactt taattttcca tctgtaagtg ttgagaaata ttgaccagct
      541 gctgaagaaa gacctatagc tgttgttaaa catgctaatg caactataat agccaataaa
      601 attttacctg tagttccaag taaagctgct gttattgcaa ctattaaagc tgtttgttga
      661 acatcttgtc catattgttg agacacagtt gctccaagat aacataatcc accataaact
      721 aatgccattc ctattactgc aattacacct gcacttattg tggctttcat cttttctttc
      781 tcacctgtat aacctttagc tattactgac atgattataa ttgatgcaaa tacactagct
      841 gccaatgcat ccattgtttg ataaccttga gttatacctt ctgcaaatac attttgtatt
      901 aaagaactgt ctcttatttc tcctaatgga gatacgatac ctttaactat taatactgcc
      961 aaagctataa gtaaagctgg agttaatatt gacccaacta tatctacaac ttttgatggt
     1021 cttattgtta aaaccaatac tagagcaaag aatactatag agaatattac tgggcttatt
     1081 ccagaaccta ttgtaggtaa tatacccatt tcataagttg ttgctgctgt tctaggtatt
     1141 gctaaaagtg gccctataca gattaccatt gcacatccta atgcaatact taatcctttg
     1201 cctgctcttg agaacatctt cgatgtgtct ccattgaact tagttgctgc tataactgct
     1261 aataatgcca aaccaccatc tgcaaaaagg aatcctatga aagctactag ccaactactt
     1321 ccagataaaa ctcctagata tggagggaag attaagttcc ctgcaccaaa aaacattgca
     1381 aatagtgcaa atccaattac aattacatct ttaaaattga tttgtttctc acccatttaa
     1441 agcaccccca tttgaatttt actacctttt actaaaaaat aagtccaatc tcttaattaa
     1501 atgaaaacct tttgacgaga ttttatttaa ttatacattt ttgacttaaa tttgtcaatt
     1561 atgtttcata atttataaaa tcttcacaat atttaataca actttcttaa ttaaacaaaa
     1621 tcaacctgta tactttaaac atagttggtt ttttgttttt tctctaattt ttcttgataa
     1681 aattaactat tccgaataat taaaatatta agacttttta gattattcga tttattatta
     1741 agttgtattg ctttatatac tgtatatatc actctccttt tttacattca tataatcttt
     1801 ttaattcaat ttaaatttta aatattttgt gtttattata taatctgaaa aaaaagcagt
     1861 caatagcatt tttaattttt ttaattttca aaattatgat tcttaaaaaa tcgttttcct
     1921 tttatcataa cacctattta cgttaattct tgtagtattt tgtatttatt ttgctaaatt
     1981 gacagttaac tttattcaat ttttattcta cttgcataga tttgcctctt gttttttact
     2041 cttaaaacca ttttttctga aaattcctta ttatgattta tcaacttatt tttcttcata
     2101 acaattactc tctaacttcc aacttactta aactttgcag ttgctagtat tcacgtttac
     2161 atacttatat gtcataatta actaaaaatt cttaatatat ctctcaatga aaacaattta
     2221 ctcatttatt taatacattt atataatcat atgtcttaaa ttttgtttta ttattttatt
     2281 attgtcacaa ttttatttat attatatttt tgtaaaaatc atttaatatg tatacttaaa
     2341 tttataaaat tactctaaaa ttctttttta atctctatta ttgttaaaaa ataaaccata
     2401 tatttttttg atattttctt atac
//
LOCUS       DAMJXI010000166         2284 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.176, whole genome shotgun sequence.
ACCESSION   DAMJXI010000166 DAMJXI010000000
VERSION     DAMJXI010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2284
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.176"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(117..1684)
                     /locus_tag="PC465_003766"
                     /pseudo
     CDS             complement(117..1684)
                     /locus_tag="PC465_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021426623.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iota toxin protein Ib"
     gene            complement(2020..2202)
                     /locus_tag="PC465_003767"
     CDS             complement(2020..2202)
                     /locus_tag="PC465_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651027.1"
                     /translation="MKKFRKHKSISNCISILLILYLTLGSLLPNNIYAQDLQSYSGKV
                     CNTTYKAPIERSEGFF"
BASE COUNT          713 a          310 c          256 g         1005 t
ORIGIN      
        1 gaatatatta gaagaagata atatttaaat aaaaaatacc ttataaagtt aattttttaa
       61 tactttataa ggtaaataca tattgtattg tggggataaa tttaaatcat ttgatactaa
      121 tcaacactaa gaaccaataa ctctctatca tcttgagtaa ttgtatatat tcttaatttc
      181 ttgtatgtca taatattttc tccacctgta aaataactcc taagattaac acaatcagtt
      241 ttaggttgat ttgtatctcc taaataatta cgcaattctt tatctttagt ttcaatatct
      301 ttaaatccaa aatattgtaa agtagcttca actctatatt tttggacata atcgagagct
      361 tctttattag tttatgttgg tgtaaaatac ataccattta tataagcctt tattgtactt
      421 ggattaaatt taaaatctgc agaatatatt ttatgtgtaa ctattatttc ttgaacagtt
      481 ggaattttaa cttctggttc atcaagtatt tcaggagtac tatttagctc tgtaatagat
      541 aagttatcta agtatattgt atcactatca attaatgcta tatttatatt agaagaatct
      601 ttttcagtag tttcaaattc ataactaaat tttgtatatc cttgttctag taccaaataa
      661 tccgtttttt cttcttttac ttttatattt acaattattg aattatatgt taaaggattt
      721 tttgaatttt actaaaaaca taacgtttat aaggttttag ttcagacata ggtattttaa
      781 tcttcgtctc accatttaat ctatttgctg agccttttaa accatcttga tttgtagtat
      841 taacattact ccatatacta gggtaattat tgtaatcatc aaaattagta aagtaagttg
      901 gtgtttttat aagtatattc attcctcttt caagtttaac attacatatt tgtttatcag
      961 acaaagtttt taaactgtct ttaatcttat tgcctatatt atcatcaaat atgagttcaa
     1021 cacaactttc atctattggt atattattaa aatataacaa accatctttt ttagtagtgc
     1081 caaaagtttt ttcaattgct tctccaattg taagttcagg tgttttatct tctgggacct
     1141 gtaaactttt agcagtaatt cttcttttgt aagattcatt ttctgtatct aatataatag
     1201 atacagaaat actgtcaatt tgacctatat cgtcttacca actatttcat tctgttacta
     1261 tttgtccaga accatttttt gtaccaaaat ttccacttac ttgtgttgtt tctaatttaa
     1321 tttgctttcc atcatctaat ttttttaatt aattataatt tataggaatc agtctagaac
     1381 taaattgata cattgtgtta agagccatag gtgaaaatcc ttttttgaga taagtatttc
     1441 caggagatag attattgcca atttgatttt cttgtgcttt gatagttgat aatgcatctc
     1501 catctaacac taaatttgtt gttggtgtca ctttgtacat aggtgcagta cctgtgttgt
     1561 agtatctaat atttgcattt atatatgcag attctccttt gtttatactt aatccagtat
     1621 ttcatgatta tccattgcta ttttgaacag cagttgaatt atctgttgta tggtaataat
     1681 ttgtcttgta tagtttcttt aaactcatta aatttttcta atgaaatttc gttttgattt
     1741 tttgttctta ttactttatt aaatgcaaat ttttctggag attcaaaata atatacatac
     1801 ataggtttat ctattttatt ttttgatata gcatttcgaa gttctctata ttctttttct
     1861 caagaatttg cttctatttg ataatcataa aaataatttc ttgtctgaga atatttgctt
     1921 atctctatag aatctttttt atatgatcct aatacttctt tttcagattt ttcaagtttt
     1981 tgatcttttc tttctcattc tttagccttt tctttatctt taaaaaaatc cttctgatct
     2041 ttctatagga gccttgtaag tagtattaca aacttttcca ctatagcttt gtaaatcttg
     2101 tgcataaatg ttattaggta acaaactacc taaagttaga tataatatca acaatataga
     2161 tatacaatta ctaatacttt tatgtttcct aaattttttc atttattctc cctacaaata
     2221 ttagtttagt taacttttga attttaattt atttagatta tataatctaa ataagaattt
     2281 ttta
//
LOCUS       DAMJXI010000167         2217 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.177, whole genome shotgun sequence.
ACCESSION   DAMJXI010000167 DAMJXI010000000
VERSION     DAMJXI010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2217
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.177"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            173..2197
                     /locus_tag="PC465_003768"
     CDS             173..2197
                     /locus_tag="PC465_003768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2651028.1"
                     /translation="MDKKKLILITYDKLNSDHYKEELTNFFGDEIIIETQNILDGIKE
                     NLEGDVVLSLSPLTSNFLIKHFKEDIEIIHGTKALSKLGYEKMMKLPPGTKSLLMTTN
                     KTSAFEMATYLYKIGINHIDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGW
                     RKISLDTYMSLLVVLKLKNEKFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTID
                     EIGDGLIFFNTFNKVTFVNKSLLNMLGLDEKLIKSPSLMEYMPNSFLDKITKNLNIDN
                     MIIYIDEIDKKFILSKKPFYLYKNIEGCLITLKDVNNIEILEQKIRSDSVKRGYVAKY
                     KFNNIIGNSSIIKDCIKKAKKMALTDNPILITGETGTGKEAFTQSIHNHSNRKNKPFV
                     AINCASLPSELLESELFGYEDGSFTGAKKGGKKGLFELAHTGTIFLDEIGDMPHDLQV
                     KLLRVLQEKEIRKIGGTSIIPIDVRILAATNKDLEKLIIENKFRMDLFYRISMFTLDL
                     PPLRKRLEDIPLLLESFLKELPYKNIKLDKSLLEALNSYTWMGNIRELRNCIEYMAYM
                     GSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLNQYDKNICISILKSLHMKPMGRTKL
                     MKFMEYNVTEYEVRNMLEYLTRNGYLISSKGRKGSSITEKGIKIIENNII"
BASE COUNT          941 a          261 c          305 g          710 t
ORIGIN      
        1 tttccttatc ttgcaaaaat aattttaaaa taggttttta taggataaaa tcctaaaaaa
       61 acctattatt taatcaaata tataaattta tactactatt tgttgtataa tataacttgc
      121 cttatacttt aaatacttta aaaataaata ctattttgtt aggagaaata aaatggataa
      181 aaagaagtta atccttataa catatgataa attgaatagt gaccactaca aagaagaatt
      241 aacaaacttt tttggagacg aaataatcat agaaacacaa aatatacttg atggaataaa
      301 agaaaattta gagggagatg tagtgctttc tctatcacct ttaactagta attttttaat
      361 aaaacatttt aaggaagata ttgaaattat tcatggaacg aaagcacttt caaaacttgg
      421 atatgaaaaa atgatgaaac tacctccagg tacaaaatcg ttacttatga caaccaataa
      481 aacttcagca tttgagatgg ctacttatct atataaaatt ggtataaatc atatagattt
      541 tgtaccgaca tatccagatt gtgatgaaat atatgattta gatacagcta taacaccagg
      601 tcagattaga tttataccaa aatacataaa aaatattgtt gatttaggtt ggagaaaaat
      661 ctcattagat acatatatgt cattattagt agtattaaaa ctaaaaaatg agaaatttat
      721 agaaaaacta tacaaattgt ccaaagagac actaagtcat gatttcttaa atacatcatt
      781 agataatata tctaaattaa aaactatact ttacatgacc attgatgaaa taggtgatgg
      841 tctaatattt ttcaacacct ttaacaaggt tacttttgta aataagtctt tacttaatat
      901 gttgggacta gatgaaaaac ttataaaatc accttcctta atggaatata tgccaaatag
      961 tttcttagat aaaattacaa agaacttaaa tatcgataat atgattatat acatagacga
     1021 aatagataaa aaattcatac tttctaaaaa accattttat ctttataaaa atatagaggg
     1081 ttgcttaatt acattgaaag atgtaaacaa tatagaaata ttagaacaaa aaataagaag
     1141 tgattctgtc aaaagaggtt atgtagctaa atataaattt aataatatta ttggaaatag
     1201 ttctattata aaagattgta ttaaaaaggc aaaaaaaatg gctcttacag ataatcctat
     1261 attaataaca ggtgaaacag gaacaggtaa agaagccttt actcagtcaa tacacaatca
     1321 ttcaaataga aaaaataaac cttttgtagc aataaattgt gcttcattac caagtgaatt
     1381 acttgaaagt gaactatttg gatatgaaga tggttctttt actggagcaa aaaaaggtgg
     1441 aaaaaaagga ttattcgaat tagctcacac tggcactata tttttagatg agataggaga
     1501 tatgccacat gatttacagg ttaaactttt aagagtctta caagaaaaag aaattagaaa
     1561 aattggtggt acaagtatta ttccaattga tgtgagaata ttagctgcca caaataaaga
     1621 tttagagaaa ttaattatag aaaataaatt taggatggat ttattttata ggataagtat
     1681 gttcacttta gatttacctc ctcttagaaa gagattagaa gatatacctc ttcttttaga
     1741 atcattttta aaagaacttc cctataaaaa cataaaactc gataagagtc ttttagaagc
     1801 tttaaattca tacacttgga tggggaatat tagagaactg agaaattgta ttgaatatat
     1861 ggcttacatg ggttccaatt atcttacaat aaatgattta cctcaaaaca tatcttcaaa
     1921 attaaataat aatcatatgt caagtaatat gtccatattc aatgatttaa accaatatga
     1981 caaaaacata tgcatttcta tcctaaaatc attgcacatg aaaccaatgg ggaggacaaa
     2041 gttaatgaaa tttatggaat ataatgtcac agaatacgaa gtaagaaata tgctagaata
     2101 tttgacacgc aatggatact taatttctag taaaggaaga aaaggctcat caataactga
     2161 gaaaggcata aaaataatag aaaataatat aatttaaacc tatagtaatt catcttt
//
LOCUS       DAMJXI010000168         1937 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.178, whole genome shotgun sequence.
ACCESSION   DAMJXI010000168 DAMJXI010000000
VERSION     DAMJXI010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1937
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.178"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            117..401
                     /locus_tag="PC465_003769"
     CDS             117..401
                     /locus_tag="PC465_003769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651029.1"
                     /translation="MLVYNKSFYPNDIFPRLDFSKIKKQLKLIDNDLSDFGSICIIEK
                     EHYTISVNSIGEINVYYDLEYENKVYRIVYEIEKLFKSQVGRFSISTYRN"
     gene            complement(558..731)
                     /locus_tag="PC465_003770"
     CDS             complement(558..731)
                     /locus_tag="PC465_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase"
                     /protein_id="HDF2651030.1"
                     /translation="MKRKLSTYFKGYILGLCIAFLLFTFILKKLIIENIIGIIIGTGI
                     AFLLIYLFNKKRK"
     gene            complement(1172..1387)
                     /locus_tag="PC465_003771"
     CDS             complement(1172..1387)
                     /locus_tag="PC465_003771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2651031.1"
                     /translation="MAIVVNLDVMMAKRKISLKDLAEKIDITNANLSILKTGKAKAIR
                     FTTLNEICKALDCQPGDILEYVEDEND"
     gene            complement(1398..1865)
                     /locus_tag="PC465_003772"
     CDS             complement(1398..1865)
                     /locus_tag="PC465_003772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HDF2651032.1"
                     /translation="MITKFFSNILSVFLYFLLSLLGVAGIIFLCMIPMFLYDFSSDKV
                     IALIARILYFFDYFIVILFLIFIINSTKYSPFVLENVKRFKVMGCCLLINTIIECING
                     YNLNTNNIRIFGTDSGGISPLMVISFIFALMCFVIAETFDKAIKIKEDNDLTI"
BASE COUNT          787 a          205 c          237 g          708 t
ORIGIN      
        1 aataaatttg tattttgttt tatataaagt aatttgaaga atatggaaaa acttgattag
       61 tacattatta attagggtat aaaatggtgt aaatagaatg ataaggggtg gatgaaatgc
      121 ttgtatataa taaaagtttt tatcctaatg acatatttcc aagattagat ttttcaaaaa
      181 taaaaaaaca gttaaaattg atagataatg acctgtcaga ttttggaagc atatgtataa
      241 tagaaaaaga acattataca ataagtgtaa acagtatagg tgaaataaat gtgtattatg
      301 atttagagta cgaaaataag gtgtatagaa tagtttatga gattgaaaag ttatttaaat
      361 ctcaagttgg aaggtttagc atatctacat acagaaattg ataattaaaa aagtagaaat
      421 taaaaaactt aatactaaag atatagataa atatatgagg taacagctag agagagttgt
      481 tacccttttt aaatactaag tatatattat tcttattaat tttttgtaaa ttcactaaaa
      541 gaccttttta tagaatatta ttttcttttt ttattaaata ggtaaatcag taaaaatgca
      601 attccagttc caattattat tccaatgata ttttctataa ttaatttttt taatataaaa
      661 gtaaataata aaaatgctat acataaacct aaaatatatc ctttaaaata ggttgaaagt
      721 tttcttttca tataatcacc aacttgtatc agatttagtt tacttaatta gagtataaca
      781 gtgttgtaac ttcaaagagt atctaaaaga ttacaaatgt tagataaaat catcaataat
      841 gtaatttata acacgtagct ataaactatg caataatata aatggaggta taagtaaatg
      901 aaaaagttcc atgttttgct aacagtttaa acaaatatta ggtagaaaag aatgtatata
      961 ggaatctgtg gtaaaattat caatttaaaa gtatgattta gtgtgataca gttcttatag
     1021 gtaatggata acaaatagat aaaggaacag tttctttctt agaacatatt ttgttatgac
     1081 tttaaacaaa gttaatatta atgtcaataa tatagtaaaa gaataaaaat catatagtat
     1141 aataaaaaag agtgtttcta aacactcttt tttaatcatt ttcatcttct acatattcaa
     1201 gtatatcacc tggctgacag tctaaagctt tgcaaatttc gtttagagtg gtaaatctaa
     1261 tagcttttgc ttttccagtt tttaaaattg ataaatttgc atttgtaata tctatttttt
     1321 ctgccaaatc tttaagtgat attttccttt ttgccatcat tacatctagg ttaactacta
     1381 ttgccataac atcacctcta tattgttaaa tcattatctt cttttatttt tatagcttta
     1441 tcaaatgttt ctgcaattac aaagcacatt agtgcaaata taaaagagat aaccataagt
     1501 ggtgagatac cgccactatc agttccaaaa attcttatat tattagtatt taaattataa
     1561 ccatttatac attcaattat agtgtttatc aataaacaac atcccattac cttaaacctt
     1621 tttacatttt caagtacgaa tggggaatac ttagtactat taattataaa tatcaagaat
     1681 aagatgacta taaagtagtc aaaaaaatat agtattcttg caattaaagc gattactttg
     1741 tcagaactaa aatcatataa aaacataggt atcatacata agaatattat accagcaact
     1801 cctaaaagtg ataatagaaa atatagaaat actgataata tattactaaa aaattttgta
     1861 atcataaaat atcatctcct ttatataaag tatattattg attataatat ataatttatt
     1921 gaatttcaat aataaat
//
LOCUS       DAMJXI010000169         1891 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.179, whole genome shotgun sequence.
ACCESSION   DAMJXI010000169 DAMJXI010000000
VERSION     DAMJXI010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1891
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.179"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            85..201
                     /gene="rrf"
                     /locus_tag="PC465_003773"
     rRNA            85..201
                     /gene="rrf"
                     /locus_tag="PC465_003773"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            208..282
                     /locus_tag="PC465_003774"
     tRNA            208..282
                     /locus_tag="PC465_003774"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:240..242,aa:Asn,seq:gtt)
     gene            287..361
                     /locus_tag="PC465_003775"
     tRNA            287..361
                     /locus_tag="PC465_003775"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:320..322,aa:Glu,seq:ttc)
     gene            367..442
                     /locus_tag="PC465_003776"
     tRNA            367..442
                     /locus_tag="PC465_003776"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:400..402,aa:Val,seq:tac)
     gene            448..524
                     /locus_tag="PC465_003777"
     tRNA            448..524
                     /locus_tag="PC465_003777"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:482..484,aa:Asp,seq:gtc)
     gene            535..609
                     /locus_tag="PC465_003778"
     tRNA            535..609
                     /locus_tag="PC465_003778"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:567..569,aa:Thr,seq:tgt)
     gene            624..708
                     /locus_tag="PC465_003779"
     tRNA            624..708
                     /locus_tag="PC465_003779"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:658..660,aa:Tyr,seq:gta)
     gene            718..791
                     /locus_tag="PC465_003780"
     tRNA            718..791
                     /locus_tag="PC465_003780"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:750..752,aa:Gly,seq:tcc)
     gene            802..878
                     /locus_tag="PC465_003781"
     tRNA            802..878
                     /locus_tag="PC465_003781"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:836..838,aa:Arg,seq:tct)
     gene            888..963
                     /locus_tag="PC465_003782"
     tRNA            888..963
                     /locus_tag="PC465_003782"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:921..923,aa:Gln,seq:ttg)
     gene            975..1050
                     /locus_tag="PC465_003783"
     tRNA            975..1050
                     /locus_tag="PC465_003783"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1008..1010,aa:Lys,seq:ttt)
     gene            1053..1141
                     /locus_tag="PC465_003784"
     tRNA            1053..1141
                     /locus_tag="PC465_003784"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1087..1089,aa:Ser,seq:tga)
     gene            1159..1249
                     /locus_tag="PC465_003785"
     tRNA            1159..1249
                     /locus_tag="PC465_003785"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1193..1195,aa:Ser,seq:gct)
     gene            1258..1334
                     /locus_tag="PC465_003786"
     tRNA            1258..1334
                     /locus_tag="PC465_003786"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1292..1294,aa:Pro,seq:tgg)
     gene            1420..1495
                     /locus_tag="PC465_003787"
     tRNA            1420..1495
                     /locus_tag="PC465_003787"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1453..1455,aa:Trp,seq:cca)
     gene            1556..1632
                     /locus_tag="PC465_003788"
     tRNA            1556..1632
                     /locus_tag="PC465_003788"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1590..1592,aa:Pro,seq:tgg)
     gene            1639..1715
                     /locus_tag="PC465_003789"
     tRNA            1639..1715
                     /locus_tag="PC465_003789"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1673..1675,aa:Ile,seq:gat)
     gene            1719..1794
                     /locus_tag="PC465_003790"
     tRNA            1719..1794
                     /locus_tag="PC465_003790"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1752..1754,aa:Phe,seq:gaa)
     gene            1802..1878
                     /locus_tag="PC465_003791"
     tRNA            1802..1878
                     /locus_tag="PC465_003791"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1836..1838,aa:Met,seq:cat)
BASE COUNT          475 a          440 c          516 g          460 t
ORIGIN      
        1 taactctaaa aaaaaataaa aaaagtattg acaaaaatag taaaaaatgt taatattata
       61 cttgtcctag caacaagaaa aaaatgtggt tataatagcg gagaagatac acctgtttcc
      121 attccgaaca cagaagttaa gttctctagc gctgatggta cttggtggga aactacctgg
      181 gagagtagga catagccacg tgaatgttcc aaggtagctc aacggtggag caaccggctg
      241 ttaaccggta ggctgtgggt tcgagcccca cccttggagc cattatggct cgttggtcaa
      301 gaggttaaga caccgccctt tcacggcggt aacaggggtt caattcccct acgagtcacc
      361 atttgtggga tcatagctca gctgggagag cacctgcctt acaagcaggg ggtcacaggt
      421 tcgagccctg ttggtcccac catttgcggc ctggtagttc agttggttag aatgccagcc
      481 tgtcacgctg gaggtcgagg gttcgagccc cttccaggtc gccaaaataa aaatgctggt
      541 gtggctcaac ggtagagcag ctgacttgta atcagcaggt tgtaggttcg attcctatca
      601 ccagctccat gtaaaactaa tacggaggat ttcccgagcg gccaaagggg gcagactgta
      661 aatctgttgt catcgacttc ggtggttcga atccaccatc ctccaccaat taaatatgcg
      721 ggtgtagctc aatggtagag ttctggcctt ccaagccagc tgtgagggtt cgatcccctt
      781 cacccgctcc aaagaaagcg tgggtgcata gctcagctgg atagagcaac gcccttctaa
      841 ggcgtgtgtc cggggttcga atccctgtgc gctcaccaca tatatattgg ggattagcca
      901 agtcggtaag gcacatgact ttgactcatg tatgcgtagg ttcgagtcct gcatccccag
      961 ccaaataaaa atatggtcta ttagctcagt cggtagagca cctgactttt aatcagggtg
     1021 tcccgcgttc gagtcgcgga tagatcacca atggagaggt gtccgagtgg tttaaggagc
     1081 tggtcttgaa aaccagtgac ttcgaaaggg gccgtgggtt cgaatcccac cctctccgcc
     1141 aaaaaaatga ctgaatttgg agaagtactc aagtggctca agaggatccc ctgctaaggg
     1201 attaggctgg gtaaccggtg cgagggttcg aatccctcct tctccgccat tcaaaaacga
     1261 ggtgtagcgc agtttggtag cgcacatggt ttgggaccat ggggccgggg gttcgagtcc
     1321 cttcacctcg accaacttaa gcttttagtt cagttggtta gagtgcccaa ctcatggcta
     1381 gtaattctag ggtttgagtc catgaaggtt attcttcata ggggtgtagc tcagttggta
     1441 gagcgtcggt ctccaaaacc gtgcgccggg ggttcgagtc cctccacccc tgccaaataa
     1501 aaaggacttg aaaaaagttg gattttagag tagtataaga tagtaaataa gatttcgagg
     1561 tgtagcgcag tttggtagcg cacatggttt gggaccatgg ggccgggggt tcgagtccct
     1621 tcacctcgac caagaaaagg gcctatagct caggtggtta gagcgcacgc ctgataagcg
     1681 tgaggtcgct ggttcgagtc cagctaggcc caccatttgc ccagatagct cagtcggtag
     1741 agcaggggac tgaaaatccc cgtgtcggtg gttcgattcc gcctctgggc accaggaata
     1801 cggcggtata gcttagttgg ctagagcgtt cggttcatac ccgaaaggtc ataggttcga
     1861 ctcctattac cgctaccatc taactatatc a
//
LOCUS       DAMJXI010000170         1838 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.180, whole genome shotgun sequence.
ACCESSION   DAMJXI010000170 DAMJXI010000000
VERSION     DAMJXI010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1838
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.180"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(301..1629)
                     /locus_tag="PC465_003792"
     CDS             complement(301..1629)
                     /locus_tag="PC465_003792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2651033.1"
                     /translation="MGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPG
                     LGILAWLIAGIITITAGLTAAEVSVAIPKTGGMMVYIKEIYGEKLGFLTGWMQIVLFY
                     PGMMAALGVIFGEQASALIGSPSLLLPIAIGIIVIVAGLNMLGSKTGGVIQTVSTICK
                     LIPLILIMVVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAG
                     EMKNPGKDLPKAIIGGLSVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSM
                     GGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPKYGIFSKLNSAQVPANAIAL
                     VSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIV
                     PIIAIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGVKR"
BASE COUNT          674 a          330 c          210 g          624 t
ORIGIN      
        1 agaaagattt aattttcata aaagctatgt ataatatttg ttgtacagat accacttagt
       61 ttgataaaaa acactttaaa ataaagtatt ttaaaataaa taatttttta gatgtttaat
      121 tttataatca aaaaactaaa aataaaatga ataccttaaa ataaactttt tagttcatgg
      181 aacgctcttt ttttgtaaaa ttaaacatat ctttacaatt ttaacaataa aaaagagact
      241 tatctctatt tgagacagtc tcttttattt taattatgaa gcatttgtaa actacttggt
      301 ttatcttttt actcctctag tcatataagc atacactggt aagcctatag ctgttattac
      361 aagacctcct atagatatca tagtagtttt catacctgca aaacacaatt gattaactac
      421 aacaaatata ccacttgcta tagctattat aggaacaata ggatataatg gaactttata
      481 ctctcttggt atatttggat gagtctttct aagtttcata acccctataa aagttaatac
      541 atagaatatc caagtagcaa atacagctaa gtcagttaat aaattaaatt gacctgacaa
      601 agcatatata gatgcaataa cagatactaa tgctattgca tttgctggaa cttgagcaga
      661 atttaattta gaaaatatac catactttgg taaagtctta tctgtagcta aagtatatgc
      721 cacccttgaa ccagttagta aaaatccatt taatgctcca aacactgaaa ttaatatacc
      781 tacagatatt atttttccac ccattgaacc aaatataact tcagcaactg ctgatgcagg
      841 agaagcataa tttgctaatt cattagctgg taatacccaa agatacgcta aatttattat
      901 aaaataaaca gccataacaa ctgataatcc acctattata gcttttggaa ggtcttttcc
      961 aggattcttc atttctccag ctaaagtacc aacattcatc catccatcaa aagcaaataa
     1021 tatagcaatt aaaacttgac ctagtacact acccaggctt aatccttcac caaccatagg
     1081 tgtaagtatt ggattatttc caccaccttt aataaatcca acaaccatta ttaaaataag
     1141 tggtattaac ttacaaattg tagaaacagt ttgtatgact cctccagttt ttgaacctaa
     1201 catattaagc cctgcaacta ttactataat tccaattgct attggaagta aaagtgatgg
     1261 actaccaatt agtgctgatg cttgttctcc aaatataaca cctaatgctg ccatcatccc
     1321 tggataaaat aatacaattt gcatccatcc agttaaaaaa cctaattttt ctccataaat
     1381 ttcttttata tataccatca ttccaccagt ttttggtatc gcaactgata cctctgcagc
     1441 tgtaagacca gctgttatag ttatgattcc agctattaac catgccaata taccaagacc
     1501 tggagctcct ccagttaatg tatagactgc ttgtggttta aaaaatacgc ccgctcctat
     1561 aacggaacca acaacagttg ataatgctgc tgatacgcca agagtctttt tcagttcatt
     1621 acttcccatt tttttcctcc tcattaatcc tatttaattt taatttcata gttaaataag
     1681 catatattat gccaatatat agaaaaatag ctttattatt tattaaaata aaataaactc
     1741 tacttagctt tcgtaatctt ttatttttag ctatgtttaa atataaaaaa attataaaaa
     1801 ccaaaaatcc aaatataata atacttctaa gtaaatgt
//
LOCUS       DAMJXI010000171         1836 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.181, whole genome shotgun sequence.
ACCESSION   DAMJXI010000171 DAMJXI010000000
VERSION     DAMJXI010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1836
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.181"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            158..1207
                     /locus_tag="PC465_003793"
     CDS             158..1207
                     /locus_tag="PC465_003793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2651034.1"
                     /translation="MFKKIVAIASSIIVSTICLTGCDFNSNDKKGESSSSKNLDKVTI
                     AEVTHSVFYAPQYAAITKGFFEDEGIKIDLINTQGADKTMAALISGEANVGLMGPEAS
                     IYVYNQNKNDYAVNFAQLTKRDGSFLVARKKMPNFSYNDLKGTEILGGRKGGVPLMTF
                     EYVLKEKGLTIGENLKVGNVNVRTDVQFGVMAGAFAGGEGDFTTAFEPTATAMEKEGS
                     GYIVTSIGKDSGEIPFTAYSTTRSYMKNNKDLIQRFTNAVYKGQLWIQQASSKEVAKA
                     MQPFFEDISLEDLTTVVDRYKSIDAWSQNPVLKEEGLKKLMTVMKEAKELDKEAPYKD
                     IVNTEFANNAIKNIK"
     gene            complement(1356..1703)
                     /locus_tag="PC465_003794"
     CDS             complement(1356..1703)
                     /locus_tag="PC465_003794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDF2651035.1"
                     /translation="MHENKKNLLDGSLAQYNDTAVPKIPVFAGNDITSEVYYFKPNQV
                     LNAHRHPNGEQIFVFLKGEGKMKLGEHECDVKNGDTVFVPTGEWHEITNGSNEEMVAV
                     QITKINAGAEYRG"
BASE COUNT          681 a          249 c          281 g          625 t
ORIGIN      
        1 atccaatatt acacattact aaaaaaacta aacataaaac tgaaaattat tattaagttt
       61 ttgtagaaat attataagca tagatacatt tttgtaacaa ctacaataaa tttttaatac
      121 tatatactat tcgtatgtct tatgggaggt atttattatg tttaaaaaaa tagtcgcaat
      181 agcaagctct atcattgtaa gtacaatatg tctaactgga tgtgatttta actctaatga
      241 caaaaaaggt gaatcttctt cgtctaaaaa tctggataaa gtaactatag cagaagttac
      301 tcactctgtt ttttatgctc cacagtatgc tgctattacg aaaggattct ttgaagatga
      361 aggtataaag attgacctta taaataccca aggtgcagat aaaactatgg cagctttgat
      421 ttcaggtgaa gcaaacgtag gtttaatggg tcctgaagca tctatatatg tatataatca
      481 aaacaaaaac gattatgcag tgaactttgc tcaattgaca aaaagagatg gtagttttct
      541 agttgctagg aaaaaaatgc ctaatttctc ttacaatgat ttaaaaggaa ccgaaatatt
      601 aggtggtaga aaaggtggag ttccactaat gacttttgaa tatgttctaa aagaaaaagg
      661 tcttactatt ggagaaaatc taaaagtagg caatgttaat gtaagaactg atgtacaatt
      721 tggtgtaatg gctggagctt ttgcaggtgg agagggtgac tttacaacag catttgaacc
      781 tacagcaaca gcaatggaaa aagaaggtag tggatatata gttacatcta taggaaaaga
      841 ttctggagaa atacctttta cagcatactc tactacgaga tcatacatga aaaacaataa
      901 agatttaatt caaagattta caaatgctgt ttataaaggt caattatgga ttcaacaagc
      961 atctagcaaa gaagtagcta aggctatgca acctttcttt gaagatatat ctttagaaga
     1021 tttaacaaca gttgtagata gatataaatc aatagatgca tggtctcaaa atcctgtatt
     1081 aaaagaggaa ggtttgaaga aattgatgac tgttatgaaa gaagctaaag aactagataa
     1141 ggaagcacct tataaagata tcgtaaatac tgagtttgca aacaatgcta taaaaaatat
     1201 taaataaaat atattagttt tagctagata ttttcttttt ttataatgaa aattaacaaa
     1261 aatataaaaa gagcctttta aaagactctt tttatatttg agattaaagt ttatataata
     1321 aaatagatat taaagtacta actgtactta tatatctatc ctctgtattc tgctccagca
     1381 ttaatttttg taatttgaac ggctaccatt tcttcattgc ttccattagt aatttcatgc
     1441 cactctcctg ttggtacaaa tacagtatct ccgtttttta catcacattc atgctcacca
     1501 agtttcattt taccttctcc ttttaggaac acaaatattt gttcaccatt agggtgtcta
     1561 tgagcattaa gaacttgatt aggtttaaaa taataaactt ctgaagttat atcgttacca
     1621 gcaaatactg gtatttttgg aactgctgta tcattatatt gagctaagct tccgtctaat
     1681 agattctttt tattttcatg catactagaa atacctcttt tctatattag atttactatt
     1741 attataccaa tataagaaaa tagtattctc actttacaca ataggaataa aattctttta
     1801 tttttaaata taagtataat actattttta tagtta
//
LOCUS       DAMJXI010000172         1741 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.182, whole genome shotgun sequence.
ACCESSION   DAMJXI010000172 DAMJXI010000000
VERSION     DAMJXI010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1741
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.182"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            1..1228
                     /gene="aph(2'')-I"
                     /locus_tag="PC465_003795"
                     /pseudo
     CDS             1..1228
                     /gene="aph(2'')-I"
                     /locus_tag="PC465_003795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="APH(2'')-Ia/If/Ih family aminoglycoside
                     O-phosphotransferase"
     gene            1212..1604
                     /locus_tag="PC465_003796"
     CDS             1212..1604
                     /locus_tag="PC465_003796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2651036.1"
                     /translation="MKLLFIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            1605..>1741
                     /locus_tag="PC465_003797"
     CDS             1605..>1741
                     /locus_tag="PC465_003797"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
                     /protein_id="HDF2651037.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     S"
BASE COUNT          717 a          133 c          298 g          593 t
ORIGIN      
        1 aaaaaaacat tatacagagc cttgggaaga tgaagttttt agagtaatta ttgaatataa
       61 caatgttcct attggatatg gacaaatata taaaatgtat gatgagttat atactgatta
      121 tcattatcca aaaactgatg agatagtcta tggtatggat caatttatag gagagccaaa
      181 ttattggagt aaaggaattg gtacaagata tattaaattg atttttgaat ttttgaaaaa
      241 agaaagaaat gctaatgcag ttattttaga ccctcataaa aataatccaa gagcaataag
      301 ggcataccaa aaatctggtt ttagaattat tgaagatttg ccagaacatg aattacacga
      361 gggcaaaaaa gaagattgtt atttaatgga atatagatat gatgataatg ccacaaatgt
      421 taaggcaatg aaatatttaa ttgagcatta ctttgataat ttcaaagtag atagtattga
      481 aataatcggt agtggttatg atagtgtggc atatttagtt aataatgaat acatttttaa
      541 aacaaaattt agtactaata agaaaaaagg ttatgcaaaa gaaaaagcaa tatataattt
      601 tttaaataca aatttagaaa ctaatgtaaa aattcctaat attgaatatt cgtatattag
      661 tgatgaatta tctatactag gttataaaga aattaaagga acttttttaa caccagaaat
      721 ttattctact atgtcagaag aagaacaaaa tttgttaaaa cgagatattg ccagtttttt
      781 aagacaaatg cacggtttag attatacaga tattagtgaa tgtactattg ataataaaca
      841 aaatgtatta gaagagtata tattgttgcg tgaaactatt tataatgatt taactgatat
      901 agaaaaagat tatatagaaa gttttatgga aagactaaat gcaacaacag tttttgaggg
      961 taaaaagtgt ttatgccata atgattttag ttgtaatcat ctattgttag atggcaataa
     1021 tagattaact ggaataattg attttggaga ttctggaatt atagatgaat attgtgattt
     1081 tatatactta cttgaagata gtgaagaaga aataggaaca aattttggag aagatatatt
     1141 aagaatgtat ggaaatatag atattgagaa agcaaaagaa tatcaagata tagttgaaga
     1201 atattatcct attgaaacta ttgtttattg atgataatat ggtttttgat attgataatt
     1261 taaaaggatt tcttaatgat accagttcat ttgggtttat agctaaagaa aataataaaa
     1321 ttataggatt tgcatattgc tatacacttt taagacctga tggaaaaaca atgttttatt
     1381 tacactcaat aggaatgtta cctaactatc aagacaaagg ttatggttca aaattattat
     1441 cttttattaa ggaatattct aaagagattg gttgttctga aatgttttta ataactgata
     1501 aaggtaatcc tagagcttgc catgtatatg aaaaattagg tggtaaaaat gattataaag
     1561 atgaaatagt atatgtatat gattatgaaa aaggtgataa ataaatgaat atagttgaaa
     1621 atgaaatatg tataagaact ttaatagatg atgattttcc tttgatgtta aaatggttaa
     1681 ctgatgaaag agtattagaa ttttatgatg gtagagataa aaaatataca ttagaatcat
     1741 t
//
LOCUS       DAMJXI010000173         1523 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.183, whole genome shotgun sequence.
ACCESSION   DAMJXI010000173 DAMJXI010000000
VERSION     DAMJXI010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1523
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.183"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            152..433
                     /locus_tag="PC465_003798"
     CDS             152..433
                     /locus_tag="PC465_003798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651038.1"
                     /translation="MASKQTPRNNLEKFLRIRVLSHTGDKIHIKLPVNFAKRMIENNA
                     LDLFNGKDDIVDGKKVTEILVKAFDYDLTGEVVHLERKNGDIIKVSIVQ"
     gene            697..951
                     /locus_tag="PC465_003799"
     CDS             697..951
                     /locus_tag="PC465_003799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651039.1"
                     /translation="MENKDFKLTICIFAFVIGVVVLFCCIGLGEFSAEHIIQQNGGIM
                     DTDQYNIYLDQSISQYRNFGSILALLGGIGILFDKYIRKY"
     gene            996..1319
                     /locus_tag="PC465_003800"
     CDS             996..1319
                     /locus_tag="PC465_003800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651040.1"
                     /translation="MATEIFTVKITPLEAQKMIKENLDADLVFSDSYNLGDDKFILIT
                     TFEKYYARNNSDAGLIVVYENTTGKTVIKATSTGSAIGILKIDWGAGGNLLKRVKNIL
                     ADYII"
BASE COUNT          651 a          109 c          238 g          525 t
ORIGIN      
        1 agatatttat taaataaata tattaaagaa gaaggaatat aaaacaagat tagaaaataa
       61 tagtgttact ttcataataa atacatataa agatattttt aagaataaaa tttattatta
      121 aataaaaaat aaaggagagt gatttaatag catggcatca aaacaaacac caagaaacaa
      181 tttagaaaag tttttaagaa taagagtctt atcacataca ggcgataaaa tacatataaa
      241 gttacctgta aattttgcaa agagaatgat tgagaataat gctttggatt tatttaatgg
      301 aaaagatgat atagtagatg gtaaaaaagt tactgaaata ttagttaaag catttgacta
      361 tgatttaact ggagaagtag ttcacttgga gagaaaaaat ggagacatta ttaaagtttc
      421 aattgtacaa tagaattatt ttatatgaat tttatttttg aatagttata aataattaga
      481 aatttgtaaa aaagtataat atattattag taatggtaca gaatacacat ttataattta
      541 tagatgtgta ttttttgttt aaaaaattta aatatataaa actataaagg ttacaatttt
      601 ggaaatagat gtaaatatat gttgtattgt ataataagag taatataaaa tctagtaaaa
      661 ataatcaaat aaatttagct tatgagaggg ataactatgg aaaataagga ttttaaatta
      721 acaatatgta tatttgcttt tgtaattgga gtagtagtat tattctgttg tataggttta
      781 ggtgaattta gtgcagagca tattattcaa caaaatggtg gaatcatgga tactgaccaa
      841 tataatattt atctagacca atctatttct caatatagaa attttggttc tatattagct
      901 ctgttaggag gaatagggat attgtttgat aaatatatca gaaaatacta gagattatgt
      961 tttgtctaaa ataaattctt atgaggagat aaaaaatggc aacagaaata tttactgtaa
     1021 aaattacacc cttagaggca caaaaaatga taaaagaaaa tcttgatgca gatttagttt
     1081 ttagtgattc ttataattta ggagatgata aatttatact aattacaact tttgagaagt
     1141 attatgcaag aaataatagt gatgcaggat taatagtagt ttatgaaaat accacaggaa
     1201 aaacagttat taaagctact tcaacaggca gtgcaattgg aattttaaaa attgattggg
     1261 gtgcaggtgg aaatttactt aaaagagtaa aaaacatact tgctgattat attatttaat
     1321 tattttatct aactgataat atgtcaagaa aatctcgtaa aagaggttaa gaacattttt
     1381 ataatatata gataaataag aatttgaagg taaagttttt aaggtataaa gaaaaataat
     1441 ataataaaac gaattggctt tataattctt tataaggcaa agagcacatt tctttatata
     1501 attgttggat attaaataat atg
//
LOCUS       DAMJXI010000174         1398 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.184, whole genome shotgun sequence.
ACCESSION   DAMJXI010000174 DAMJXI010000000
VERSION     DAMJXI010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1398
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.184"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            129..938
                     /locus_tag="PC465_003801"
     CDS             129..938
                     /locus_tag="PC465_003801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2651041.1"
                     /translation="MNKIINNILNTCKQYTYILPHKLLRQYIAHYTISIPDTSIKENL
                     TLIPDASGCMIFKFDKKGIESAFWGATTKTTIVKNDIENVLFRVFVEFRPGGVYYLTG
                     LSQRESTDLKISLEDFNTLFSLEVNSIFERTSTIKELVEQLDMLFLSYLLKSNIVDMT
                     IPILENARKQNSIMSVKNISQISCYSERHLNRIFNNSLGMSVKSYLRLLRINLVLQEI
                     QNNKIPFATLAQDIGYYDQSHFINDFKSICGVNPTTYIKNLSDFYNEKYKF"
     gene            980..1246
                     /locus_tag="PC465_003802"
     CDS             980..1246
                     /locus_tag="PC465_003802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HDF2651042.1"
                     /translation="MIESRCGILCYECGYKEKVNCKGCTEIEKPFWGEQCPVKSCCED
                     KNLTHCGLCDTFPCEMLNQFAYDKEQGDDGKRISQCKKWAVLAL"
BASE COUNT          553 a          159 c          193 g          493 t
ORIGIN      
        1 actttacaat tattgtatct aaatttaaca aaatatctta ttagaatatt tcaattaaaa
       61 caaaactggt ttattatata aaaaataaat tagtatactt attttttata tatcaggagg
      121 atatacttat gaataaaata atcaataaca ttttaaatac ctgcaaacag tatacatata
      181 ttttgccaca taaattgtta agacagtata tagcacacta tacaatatct attccagata
      241 caagtattaa agaaaatctt acattaatac ctgatgctag tggatgtatg atatttaaat
      301 ttgacaaaaa aggtatagaa agcgcattct ggggagccac aacaaaaact actattgtaa
      361 aaaatgatat agaaaatgta ctttttagag tattcgttga gtttcgccca ggtggagtat
      421 attatttgac aggtctttct caaagagaat ctacagattt aaaaatttca cttgaagatt
      481 ttaacacatt atttagctta gaggttaatt ccatttttga aagaacaagt actataaagg
      541 aattagtaga acaattagat atgttattct tatcatactt attgaaatca aatatagtag
      601 atatgactat accaattctt gaaaatgcta gaaaacaaaa ctctattatg tctgttaaaa
      661 acatttcaca aattagttgt tatagtgaac gacatttaaa tagaattttt aataattctc
      721 ttggtatgag tgttaaatca taccttagat tacttcgtat aaaccttgta ttacaagaaa
      781 tacaaaataa taaaatacca tttgcaactt tagcacaaga tattggttat tacgaccaat
      841 ctcattttat aaatgatttt aaatctattt gtggtgttaa tccaacaacc tatataaaaa
      901 atttgtccga tttttacaat gaaaagtata aattttgata tacaatcata taaaatttat
      961 atttaaggag tgacttaaaa tgatagaatc aagatgtgga attttatgtt atgaatgtgg
     1021 atacaaggaa aaagtcaatt gtaaaggttg tacagagatt gagaaaccat tttggggtga
     1081 acaatgtcct gtaaaatctt gttgtgaaga taaaaacctt acacattgtg gtctatgtga
     1141 tacatttcca tgtgaaatgc ttaatcaatt tgcatatgac aaagaacaag gtgatgatgg
     1201 caaaagaatt tctcagtgca aaaaatgggc tgtactagcc ttataatata ctctcttgtt
     1261 ataaaataag tttttgtaag gtaaattttt taaactgttg tagaaatttc tgcaacagtt
     1321 tttataatta aatttaaagg ttatttaatt aaattaatag aatagtaatt tattgataaa
     1381 atctgattac taaaattg
//
LOCUS       DAMJXI010000175         1337 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.185, whole genome shotgun sequence.
ACCESSION   DAMJXI010000175 DAMJXI010000000
VERSION     DAMJXI010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1337
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.185"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            27..101
                     /locus_tag="PC465_003803"
     tRNA            27..101
                     /locus_tag="PC465_003803"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..200
                     /locus_tag="PC465_003804"
     tRNA            116..200
                     /locus_tag="PC465_003804"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            210..293
                     /locus_tag="PC465_003805"
     tRNA            210..293
                     /locus_tag="PC465_003805"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:244..246,aa:Leu,seq:tag)
     gene            323..399
                     /locus_tag="PC465_003806"
     tRNA            323..399
                     /locus_tag="PC465_003806"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:357..359,aa:Arg,seq:tct)
     gene            407..482
                     /locus_tag="PC465_003807"
     tRNA            407..482
                     /locus_tag="PC465_003807"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:440..442,aa:Gln,seq:ttg)
     gene            571..659
                     /locus_tag="PC465_003808"
     tRNA            571..659
                     /locus_tag="PC465_003808"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:605..607,aa:Ser,seq:tga)
     gene            663..738
                     /locus_tag="PC465_003809"
     tRNA            663..738
                     /locus_tag="PC465_003809"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:696..698,aa:Phe,seq:gaa)
     gene            745..818
                     /locus_tag="PC465_003810"
     tRNA            745..818
                     /locus_tag="PC465_003810"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:779..781,aa:Met,seq:cat)
     gene            833..909
                     /locus_tag="PC465_003811"
     tRNA            833..909
                     /locus_tag="PC465_003811"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:867..869,aa:Ile,seq:cat)
     gene            933..1009
                     /locus_tag="PC465_003812"
     tRNA            933..1009
                     /locus_tag="PC465_003812"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:967..969,aa:Pro,seq:tgg)
     gene            1017..1093
                     /locus_tag="PC465_003813"
     tRNA            1017..1093
                     /locus_tag="PC465_003813"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1051..1053,aa:His,seq:gtg)
     gene            1102..1177
                     /locus_tag="PC465_003814"
     tRNA            1102..1177
                     /locus_tag="PC465_003814"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1135..1137,aa:Lys,seq:ttt)
     gene            1185..1258
                     /locus_tag="PC465_003815"
     tRNA            1185..1258
                     /locus_tag="PC465_003815"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1217..1219,aa:Cys,seq:gca)
     gene            1265..1336
                     /locus_tag="PC465_003816"
     tRNA            1265..1336
                     /locus_tag="PC465_003816"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1297..1299,aa:Asn,seq:gtt)
BASE COUNT          321 a          309 c          355 g          352 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atgtaaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccacca aaaaaatgcg cggatgtggc ggaattggca gacgcactag
      241 acttaggatc tagcgccatt ggcgtggggg ttcgactccc ttcatccgca ccatttttgt
      301 ttgatataca tatataaatt gtgggtgcat agctcagctg gatagagcaa cgcccttcta
      361 aggcgtgtgt ccggggttcg aatccctgtg cgctcaccac atatattggg gattagccaa
      421 gtcggtaagg cacatgactt tgactcatgt atgcgtaggt tcgagtcctg catccccagc
      481 caaatgatgt attactaagc tatatttgaa ttatttttat tttaaatata gttaggttca
      541 attttagaat aagtttaagt atccgaatgt ggagaggtgt ccgagtggtt taaggagctg
      601 gtcttgaaaa ccagtgactt cgaaaggggc cgtgggttcg aatcccaccc tctccgccaa
      661 atgcccagat agctcagtcg gtagagcagg ggactgaaaa tccccgtgtc ggtggttcga
      721 ttccgcctct gggcaccaaa atatggcggt atagcttagt tggctagagc gttcggttca
      781 tacccgaaag gtcataggtt cgactcctat taccgctact aaaatttaat gtgggccatt
      841 agctcagttg gttagagcgc ccggctcata accggtaggt ctggggttcg agtccctgat
      901 ggcccaccac attaaattaa ttaatataaa ttcgaggtgt agcgcagttt ggtagcgcac
      961 atggtttggg accatggggc cgggggttcg agtcccttca cctcgaccaa tataaggtgg
     1021 gtatagctca gttggttaga gcgccagatt gtggctctgg aggtcgtgag ttcgactctc
     1081 attatccacc ccaattcata tggtctatta gctcagtcgg tagagcacct gacttttaat
     1141 cagggtgtcc cgcgttcgag tcgcggatag atcaccaaaa aggtggcgac atagccaagt
     1201 ggtaaggcag tggactgcaa ctccttgatc cccagttcga atctgggtgt cgcctccaaa
     1261 atattccaag gtagctcaac ggtggagcaa ccggctgtta accggtaggc tgtgggttcg
     1321 agccccaccc ttggagc
//
LOCUS       DAMJXI010000176         1311 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.186, whole genome shotgun sequence.
ACCESSION   DAMJXI010000176 DAMJXI010000000
VERSION     DAMJXI010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1311
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.186"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            55..171
                     /gene="rrf"
                     /locus_tag="PC465_003817"
     rRNA            55..171
                     /gene="rrf"
                     /locus_tag="PC465_003817"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            179..253
                     /locus_tag="PC465_003818"
     tRNA            179..253
                     /locus_tag="PC465_003818"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:211..213,aa:Asn,seq:gtt)
     gene            259..344
                     /locus_tag="PC465_003819"
     tRNA            259..344
                     /locus_tag="PC465_003819"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:293..295,aa:Leu,seq:taa)
     gene            360..435
                     /locus_tag="PC465_003820"
     tRNA            360..435
                     /locus_tag="PC465_003820"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:393..395,aa:Met,seq:cat)
     gene            443..517
                     /locus_tag="PC465_003821"
     tRNA            443..517
                     /locus_tag="PC465_003821"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:476..478,aa:Glu,seq:ttc)
     gene            532..605
                     /locus_tag="PC465_003822"
     tRNA            532..605
                     /locus_tag="PC465_003822"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:564..566,aa:Gly,seq:tcc)
     gene            611..686
                     /locus_tag="PC465_003823"
     tRNA            611..686
                     /locus_tag="PC465_003823"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:644..646,aa:Val,seq:tac)
     gene            692..768
                     /locus_tag="PC465_003824"
     tRNA            692..768
                     /locus_tag="PC465_003824"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:726..728,aa:Asp,seq:gtc)
     gene            779..853
                     /locus_tag="PC465_003825"
     tRNA            779..853
                     /locus_tag="PC465_003825"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:811..813,aa:Gly,seq:gcc)
     gene            863..936
                     /locus_tag="PC465_003826"
     tRNA            863..936
                     /locus_tag="PC465_003826"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:897..899,aa:Arg,seq:tct)
BASE COUNT          389 a          264 c          299 g          359 t
ORIGIN      
        1 ctaggttcta taaacttatt aaaaacttaa tagaaatatt aagcataaag attatgtggt
       61 tacaatagca gagaggatac acctgttccc attccgaaca cagaagttaa gctctctagc
      121 gctgatggta cttggtggga aactgcctgg gagagtagga cgtagccacg ttaaatgttc
      181 caaggtagct caacggtgga gcaaccggct gttaaccggt aggctgtggg ttcgagcccc
      241 acccttggag ccaaaaaagc cgaagtggcg gaactggcag acgcacagga cttaaaatcc
      301 tgcgggactt acctctcgta ccggttcgat tccggtcttc ggcacttata aaacaatatc
      361 gcggggtgga gcagttggca gctcgtcggg ctcataaccc gaaggtcgta ggttcaagtc
      421 ctgcctccgc aaccattaaa acggctcgtt ggtcaagagg ttaagacacc gccctttcac
      481 ggcggtaaca ggggttcaat tcccctacga gtcaccaatt caattaaata tgcgggtgta
      541 gctcaatggt agagttctgg ccttccaagc cagctgtgag ggttcgatcc ccttcacccg
      601 ctccaaaaat gggaccatag ctcagctggg agagcacctg ccttacaagc agggggtcac
      661 aggttcgagc cctgttggtc ccaccattcg cggcctggta gttcagttgg ttagaatgcc
      721 agcctgtcac gctggaggtc gagggttcga gccccttcca ggtcgccaaa ttaaataagc
      781 gggaatagtt cagtggtaga gcgcaacctt gccaaggttg aagtcgcgag ttcgaatctc
      841 gtttcccgct ccataataac ttgggtgcat agctcagctg gatagagcaa cgcccttcta
      901 aggcgtgtgt ccggggttcg aatccctgtg cgctcattaa gaaaagttta ctataaatta
      961 tagtaaactt ttatattgtt taaaaagaca caggaaacat gtatattacc tgtgtctttt
     1021 tatttataaa ctttaaacta tgtaaaaatt acagtatatt ctaatagagt tacagtatat
     1081 tcattaatat tgtaaacata cggagggtaa tgtataatag tctacaagat gtttatgaag
     1141 gcatcagtta aatataataa atataactaa ttagtaagag ttatatacat tatattgtat
     1201 actttatggt atttatatat tgaaataact tatgaagtta tttataaaga gattcatgag
     1261 catatttttg tctaaacaat aagtataaga aattataaaa aattagagac t
//
LOCUS       DAMJXI010000177         1251 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.187, whole genome shotgun sequence.
ACCESSION   DAMJXI010000177 DAMJXI010000000
VERSION     DAMJXI010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1251
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.187"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            10..273
                     /locus_tag="PC465_003827"
     CDS             10..273
                     /locus_tag="PC465_003827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651043.1"
                     /translation="MIKNTKQITVEVNEILLQEMSKITNDENNILTDLINESIVNYIL
                     ENKKHNIENKDLEEVIKFYKKENTEKPKSAARAIAEAKTHTLY"
     gene            complement(710..1087)
                     /locus_tag="PC465_003828"
     CDS             complement(710..1087)
                     /locus_tag="PC465_003828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2651044.1"
                     /translation="MTITKIPPAELKVMKFIWSSDFTVASKDVIEAMEKLYNWKQTTT
                     LTLLSRLVNKQFLSARKIDRHTHYTVLIGEEEYLHFETKTFLDNMHGSSIESFMKSLF
                     KKGVNEEELNSVEKWVKDIKKDE"
BASE COUNT          519 a          169 c          105 g          458 t
ORIGIN      
        1 gtggttgata tgataaaaaa tacaaaacaa attacagtag aagttaatga aattttatta
       61 caagaaatgt ctaagataac taatgacgaa aataatattt tgacagattt gataaatgaa
      121 tcaattgtaa attatattct tgaaaacaaa aaacataata ttgaaaataa agatttagaa
      181 gaagtgatta aattttacaa aaaagaaaat actgaaaaac ctaaaagtgc agcaagagct
      241 atagctgaag caaaaactca tactctgtat taatcaaata aaaaagttcc taaaaactag
      301 gaactttttt atattaataa ttattaatat atctcaatat ttatctcaaa tctatcaata
      361 taagcatgtt taatacaatc tattgtatac ttatcttacc ctagaaataa tcaaaacaaa
      421 aataaaatta tgccctttat atctaaaaca attaatttac atgattaata tacaaaaatt
      481 ctgactttta aattcgtata caatatcaaa ctaaaataat attaatgaca aacccaatat
      541 aaattaaatt caaacaggtt tgattttaca tcaaacttat tgtattaata ttaaataaca
      601 agacaaaaat atttataaaa atcacaaatt ttacataaaa ctttatattt gattcattta
      661 actaattatt gtaaaaacta tttattttat gataattaac tacaccaaat tattcatctt
      721 ttttaatatc cttaacccat ttttcaacag agttcaattc ttcttcattt accccctttt
      781 tgaacaagga tttcataaaa ctctcaatag aacttccatg catattatct aaaaaagttt
      841 ttgtttcaaa atgtaaatac tcttcttctc caataagaac tgtataatgt gtatgtctat
      901 caatttttct tgcacttaag aattgcttat ttactaatct tgataaaagt gttagtgttg
      961 tagtttgctt ccaattatat agtttttcca tagcttcaat gacatctttt gatgctactg
     1021 taaaatctga actccaaata aatttcatga cttttaattc tgctggtggt atcttagtaa
     1081 tagtcatatg attttacact cctctcaaac ttctacataa ttaaatacta tattaataga
     1141 cttttcgagt caaaggtttt atttaaaata tctcatccaa atttattaat acaaaaaatt
     1201 tatattttta ttcaaaatta aacacacaat ctattaatat aaagataaat a
//
LOCUS       DAMJXI010000178         1248 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.188, whole genome shotgun sequence.
ACCESSION   DAMJXI010000178 DAMJXI010000000
VERSION     DAMJXI010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1248
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.188"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            116..1156
                     /locus_tag="PC465_003829"
     CDS             116..1156
                     /locus_tag="PC465_003829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HDF2651045.1"
                     /translation="MNLNLTNTINLMKKYLDIPSPAGYTENAVLEIKKDFENLGLDTI
                     LTKKGALIATLPGEDDSNQITISAHMDTLGAIVKEISSDGTLKYHKVGGGCWAAIEGE
                     NCTVITRKGKKIRGSVVFKYASTHIYGQTKAATERNEETMIIRLDEKVFTKQDVLDLG
                     ISVGDFVCLDHRFEATESGFIKSRYIDNKSAVAMVLEICRYFKENNLTPKHTTNFYIS
                     NYEEIGHGVSKCLPEKTKEFVAIDIAPTGPSQTSSEHGVTIVAKDNLSLYDFNLRNKL
                     VDVAEDNNLDYAVDVFTFYGSDASEAIRWGEDVQIACVGPGTNNSHHYERTHIEAIEN
                     TLKLLINYMLKE"
BASE COUNT          479 a          145 c          198 g          426 t
ORIGIN      
        1 ttttatatac ttttttttta aatatgttta gattctattc ttttaatttt agttttcaga
       61 acatttgtat ttatgttata atttgtataa atatatttat ttaggaggaa acaatatgaa
      121 tttaaattta actaatacta taaatttaat gaaaaaatat ttggacattc caagcccagc
      181 tggatatact gaaaatgcag ttttagaaat caaaaaagat tttgaaaatt taggtcttga
      241 cactattctt acaaaaaaag gtgcacttat agctactctt cctggtgaag atgattcaaa
      301 tcaaataaca atatctgcac atatggatac acttggagct atagtaaaag aaatatcatc
      361 tgatggtact cttaaatacc ataaagttgg tggtggatgt tgggcagcta tagagggaga
      421 aaactgtact gttataacta gaaaaggtaa aaaaatcaga ggaagtgttg tatttaagta
      481 tgcttctact catatatatg gtcaaacaaa agctgccact gaaagaaatg aagaaacaat
      541 gattattaga cttgatgaaa aagtatttac aaagcaagat gtattagatt taggaataag
      601 tgttggggat tttgtatgcc tagaccatag atttgaggct acagaatctg gttttataaa
      661 atctagatat atagataata aatcagctgt agcaatggtt cttgaaatat gtagatattt
      721 taaagaaaac aatttaacac ctaagcatac tactaacttt tatataagta attatgaaga
      781 aattggacat ggtgtttcta aatgtttacc tgaaaaaaca aaagaatttg tagcaataga
      841 tatagcacct actggaccaa gtcaaacatc tagtgaacat ggtgtaacta tagttgcaaa
      901 agataattta tcattatatg attttaattt aagaaacaag cttgtcgatg ttgcagaaga
      961 caataattta gactacgctg tcgatgtatt tactttctat ggttcagatg cttcagaagc
     1021 tattcgttgg ggagaagatg ttcaaatagc atgtgttggt cctggaacaa acaatagtca
     1081 ccattatgaa agaacacata tagaagctat tgaaaataca ctaaaattac ttataaatta
     1141 tatgcttaaa gaataattaa ttatatattt taccaaagtc aattcttaac aaataattaa
     1201 ctttaatttt tatttttata caaaaattgg tttttctata gacttaat
//
LOCUS       DAMJXI010000179         1233 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.189, whole genome shotgun sequence.
ACCESSION   DAMJXI010000179 DAMJXI010000000
VERSION     DAMJXI010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1233
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.189"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            260..1233
                     /locus_tag="PC465_003830"
                     /pseudo
     CDS             260..1233
                     /locus_tag="PC465_003830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          538 a          129 c          191 g          375 t
ORIGIN      
        1 catgaaagtg taagaagttc ataagagaac tgcataggta gtagcgagct tatgtgaacg
       61 acaacctcaa aaatgataaa agttaagact tacggttctt aaatatgtta tttaaaatta
      121 aatataaaac cttctaaata attgttttaa ataattacat ttgttaatat tatgataggt
      181 ggttaataaa ttgttcacca cagcattata taatatatta aaatcattaa aaagtgtatc
      241 aaaaaacaat taaagtgagg tgatagcagt gaaaaaagct tataagttta gactgtatcc
      301 aaataaaaag caacaagagt taattaacaa aacttttgga tgttgtagat ttgtatataa
      361 taagtatctt gctaaaagaa tagatgttta taaaaacaat aaagaaactt ttacttataa
      421 acagtgtagt tctgatttga ccaatttaaa aaaagaatta aaatggctta aagaacctga
      481 caaattttca ctacaaaacg ccttaaaaga tttagataat gcatataaaa aattctttaa
      541 agaaaaagca ggatttccta aatttaaatc aaagaaaatt aatagatttt catataaaac
      601 taactttaca aatggaaaca ttatgtattg tggtcaacat ataaaactac ctaaacttgg
      661 tatggttaag gtaagggata aacaagtacc taaagggaga atacttaatg ctactatatc
      721 taaagagcca agtggtagat attgaagcat ttgaaaatac taataatcag ataggtttag
      781 atttaggaat taaagaattt tgtatctcaa gttgtggaga atttatagaa aatcctaagt
      841 atcttaagaa gtcattaaac aaacttgcta aattacaaag agaattatcg agaaaaacaa
      901 tcggtagttt aaatagaaat aaagcaagat taaaagttgc aagatttcaa gaacatatag
      961 ctaatcaaag aaatgatttt ctacaaaaac tatctactaa attaataaaa gagaatgata
     1021 ttatttgcat agaagattta caagtaaaga atatgattag aaatcgtaaa ctatctcgct
     1081 taatttcaga tgtatcatgg tcagaattta ttcgtcaatt agaatacaag gctaattggt
     1141 atggtagaca aattgtaaag gtaggtaaat tctttgcaag ttcacaaata tgcaataaat
     1201 gtgggtataa aaacgaggaa gtgaaggact taa
//
LOCUS       DAMJXI010000180         1232 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.190, whole genome shotgun sequence.
ACCESSION   DAMJXI010000180 DAMJXI010000000
VERSION     DAMJXI010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1232
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.190"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            39..296
                     /locus_tag="PC465_003831"
     CDS             39..296
                     /locus_tag="PC465_003831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651046.1"
                     /translation="MIIIRSQDKTNLMQINQIKIDGSQVYAVFESKIDTVKIGDYENN
                     TRAIQVLDNIQNFIENGTKYDYITSNKVRYNVNKIFQMPAK"
     gene            complement(406..1086)
                     /locus_tag="PC465_003832"
     CDS             complement(406..1086)
                     /locus_tag="PC465_003832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDF2651047.1"
                     /translation="MIWTFYSFICVILPCLIYQIVVIKRKNLKVEKNVMIHLVWVYIF
                     LLYIYLALSKAGIGSIWDIGRYSGLFRIDEINLIPFDSVGILTYILNIIMFMPLGFLL
                     PLIWKNFRNIINVSLTGLGFSLAIELCQLFNLRATDIDDLMMNTLGAVLGYLIWVGVN
                     NLFNLIKKKDIFPSIYKNIIQDEIAITIDDDISEKITSLYKNEAIIYLILAVLGEFLL
                     FNWSIIPY"
BASE COUNT          511 a          148 c          135 g          438 t
ORIGIN      
        1 tagaaattaa aatgaattaa gtaaatggag gaattgatat gataataatt agaagtcaag
       61 ataaaactaa tttaatgcag ataaaccaaa ttaaaataga tggtagtcaa gtttatgcag
      121 tatttgaaag taaaattgat actgtaaaaa taggagatta tgaaaataat acaagagcta
      181 tacaagtgtt ggacaatata caaaacttca ttgaaaatgg aacaaaatat gattatataa
      241 catcaaataa agtcagatac aatgttaata aaatatttca gatgccagct aaatagtgag
      301 tgtgcatttt aatttaataa ctaaagccca ctttcttttg tagtatgaaa gagggcttta
      361 catatttgta aatatcgaag tacacttgtt ttatcaataa attatttaat aaggtataat
      421 ggaccaatta aacaataaaa attctcctaa aacagcaagt attaaatata taatagcttc
      481 atttttgtaa agagaggtaa ttttttcgct tatgtcatca tcaattgtaa tagcaatttc
      541 atcttgaata atatttttat atatagatgg gaaaatatct tttttcttta taagattaaa
      601 taaattattt acacctaccc atatcaaata tcctaaaaca gcacctaatg tgttcatcat
      661 taaatcatca atatctgtag ctcttaagtt aaacaattga caaagttcaa ttgctaatga
      721 aaaacctaat ccagttaatg aaacattgat aatatttcta aaatttttcc aaattaaagg
      781 tagtaaaaat cctaaaggca taaacataat tatatttaaa atatatgtta agatgccaac
      841 tgagtcaaaa ggtattagat ttatttcatc aattctaaaa agcccactat accttcctat
      901 atcccatatg ctaccaattc cagctttact aagtgctaga tagatatata ataaaaaaat
      961 atatacccat actaaatgta tcattacatt cttttcaact ttcaaatttt ttcgttttat
     1021 aacgactatt tggtatatta agcatggtaa tataacgcaa ataaatgaat aaaatgtcca
     1081 tatcatttta ttttgtcccc tttcaaattt atgtttttag ttttataagt actatcttta
     1141 tattaaactg taagttttaa aaatctttta ataaaatctt aaaaatttat taatttataa
     1201 aaatatatta ttaagattaa aaatatatat aa
//
LOCUS       DAMJXI010000181         1213 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.191, whole genome shotgun sequence.
ACCESSION   DAMJXI010000181 DAMJXI010000000
VERSION     DAMJXI010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1213
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.191"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            297..977
                     /locus_tag="PC465_003833"
     CDS             297..977
                     /locus_tag="PC465_003833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2651048.1"
                     /translation="MQIDVLIIDGDKNSSQELKNFLEGKGINVYLAYNCKDAIIKIFS
                     KKFDLIFLEIILVDGDGWDFCKKIRNITTCPIIHITYINENQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRRDLFLNNNKNNIKLEDYNRASGVIKLENKMIKLTPTENRLL
                     NYFIENAEKTLTIKEIYEHVWMNEYLDDNYSVVVAVSGLRKKIEKDYKNPQKIITIRE
                     VGYYFNKI"
BASE COUNT          546 a           76 c          184 g          407 t
ORIGIN      
        1 ataaaaaata tagctttgaa ttatataatt gtatatgctt atctttatac agtaaataaa
       61 aaatcaaatg aaataccaaa taaagtgtat atcttaaaat aacttactag agatacaagg
      121 atgctatgtg aattttgaag tgtgcagttt agataataaa tatatataaa taataaagaa
      181 aatggattta tagtatttaa aatttcttat aagggtaaaa aatgctatta gaaaatgtac
      241 taaaaatatt tttccaattc tttatagaaa aataatgata tttaggagag attgtaatgc
      301 aaattgatgt attgataatt gatggagata agaatagttc tcaagagctg aaaaattttt
      361 tagaaggaaa ggggataaat gtctatttag catataattg taaagatgct attataaaaa
      421 tatttagcaa gaaatttgac ttaatatttt tagagataat tttagttgat ggtgatggtt
      481 gggatttttg taaaaaaatt agaaatataa ctacttgccc aattattcat ataacttata
      541 taaatgaaaa tcaaagtatt ttaaatgctt taaattctgg aggagatgat tatttaataa
      601 agcctttaaa tttagaaata ttatatgcga aagtgaaagc tattttaaga agaagagatt
      661 tatttttaaa taataataaa aataatataa aactagaaga ttataataga gctagtggag
      721 taataaagtt agaaaataaa atgataaagt taactccaac agaaaataga ttattaaatt
      781 actttataga gaatgctgaa aagactctaa ctattaagga gatatatgaa catgtatgga
      841 tgaatgagta tttagatgat aattatagtg tagtggttgc tgtgagtgga ttaagaaaga
      901 aaatagagaa agattataaa aatcctcaaa aaattataac gataagagaa gtagggtatt
      961 actttaacaa gatataaagc tttataaaca gaatgaatga taaggcatag ataatatgtt
     1021 agtatattac aagagttttt gttctaacga tatatttgta aaattagatt taatttactt
     1081 aattaaatta tagcagtaga ataaatataa aaaatgtctg aaatattata gacatcagta
     1141 aaatatataa aactataata taagtcgtaa taataaaaca aatgaatatt aattaataaa
     1201 aagatagtag cta
//
LOCUS       DAMJXI010000182         1148 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.192, whole genome shotgun sequence.
ACCESSION   DAMJXI010000182 DAMJXI010000000
VERSION     DAMJXI010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1148
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.192"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(278..1024)
                     /gene="cdtR"
                     /locus_tag="PC465_003834"
     CDS             complement(278..1024)
                     /gene="cdtR"
                     /locus_tag="PC465_003834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family response regulator CdtR"
                     /protein_id="HDF2651049.1"
                     /translation="MDILIFDNDVCFGMKLKEKINNILIKEGFDNDVVRLYHNANLLL
                     KELTEKNKVRIYFIVVDAKYKISNELCDGLWIAQKIRESDYISPIIFLTNHIEMILGI
                     FDYRLEVMDFILKHDMEIAESKIKACIKIAHKRYIKEKNYRSNFFTIYSDFSLWKISF
                     DEVIYFETSTIPHKIKLVTTSRIFEFYKSLKSLPDLDACFIRVHKSFVVNKYHIVSLD
                     LKKNNIKMSNGHICRISNTYRNILKNIIKT"
BASE COUNT          428 a          140 c          120 g          460 t
ORIGIN      
        1 aacataaaaa tatgtattta tatgatatgt cagtacaaaa taacaactga atattttaaa
       61 gagactattt cgtactttta tgatttaatg agctatctta tcgaatcata atctaggaac
      121 aattgttata atatctaata gtagttatat atgatatagt cagtatgtgt tttttcacaa
      181 tatgattatt atatagagga ttcttaggga ttactctttt tgtataaaaa agagatggtt
      241 caaattttta tcttgagaca tctccttttt ctatttatta tgttttaata atattcttta
      301 aaatatttct atatgtatta gatatacgac atatatggcc attactcatt ttaatattat
      361 ttttctttag gtcgagagaa acaatatgat atttattaac tacaaaagat ttatgtacac
      421 ggataaagca tgcatctaaa tctggtaaag actttaaact tttatagaat tcaaatattc
      481 tagaagtagt cactaatttt attttatgtg gaatagtgct tgtttcaaaa tatataactt
      541 catcaaatga aattttccat agtgagaaat ctgaatagat agtaaaaaaa ttagagcgat
      601 aatttttttc tttaatgtat cttttgtgag caattttaat acaagctttt attttacttt
      661 cagcaatttc catatcatgt tttagtataa agtccataac ttctaaccta taatcgaaga
      721 tccctaaaat catttctata tgatttgtaa gaaatatgat tggactaata taatctgatt
      781 ctctaatttt ttgtgctatc cataatccat cacataattc attacttatc ttatattttg
      841 cgtctacaac tataaaatat attcttactt tatttttttc agtaagctct tttaataaca
      901 aatttgcatt atgatataat cttacaacat cattatcaaa accttctttt attaaaatat
      961 tatttatttt ttcttttagt ttcattccaa aacaaacatc attatcaaag attaatatat
     1021 ccactaaata ccctcctata aaaaattcaa aagtaaaaaa acaaaagtat tttatagaaa
     1081 atacataaaa taacactagg agataaataa gattaaggat agttagaatt aaggtatatt
     1141 tatgcttg
//
LOCUS       DAMJXI010000183         1141 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.193, whole genome shotgun sequence.
ACCESSION   DAMJXI010000183 DAMJXI010000000
VERSION     DAMJXI010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1141
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.193"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(190..900)
                     /locus_tag="PC465_003835"
     CDS             complement(190..900)
                     /locus_tag="PC465_003835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2651050.1"
                     /translation="MTSICICDDEKQQRNMLNKIITREMDLWGYPYQIKEYSNGESLV
                     YNLEHENYYIDIIFLDIELGKSNGVDIAKTIRKHSKDTIIIFVTGFSDYVFHGYDVGA
                     LNYILKPYKTEKICKVLKEALKKLEQWKENFITVQIGTNLCKINTKDILYFKSELRKL
                     TVVTFDKTLEYYGKLNDMETVLPSNFIRTHQRYIVNLNHVDSITQTYAKVQNEKIPIS
                     RKKYQEVVGKFTRYMLES"
BASE COUNT          412 a          152 c          121 g          456 t
ORIGIN      
        1 aaactgagct ttaaaaaatt aagtttgaaa aaaactctaa aaactaagct tcaaaaaatt
       61 aaattttgaa agattgaaat tctagaaatt aatcttcaaa aaattaaatt tgaaaaaaca
      121 aaactctaaa aactaagctt taaaaaatta agtttcaaaa ataaaattct agagattgaa
      181 cttcaaaaat taagattcta acatatacct tgtaaatttt cctacaacct cttgatattt
      241 tttacggctt ataggaattt tttcattctg aactttggca taagtttgag ttatactatc
      301 tacatggttt agattgacaa tatacctttg atgcgtacgt ataaaattag agggaagaac
      361 agtttccata tcatttaatt ttccgtagta ttctaatgtt ttatcaaagg taactacagt
      421 taattttctt agctcacttt taaagtagag gatatctttt gtattaattt tacaaagatt
      481 agttccaatc tgaactgtaa taaagttttc tttccattgt tctaattttt ttagtgcttc
      541 ttttaatact ttacatattt tttcagtttt ataaggtttt aagatgtagt tcaaagctcc
      601 tacatcatat ccatgaaata catagtcaga aaaacctgtg acaaagatga ttatagtatc
      661 ctttgaatgt tttcgtatag tttttgctat gtcaacgcca ttactttttc caagttcaat
      721 atctaaaaaa ataatatcta tgtaataatt ttcgtgttct agattgtata ctagactttc
      781 tccatttgaa tattctttta tttggtaggg gtagccccac aaatccattt ctcttgtaat
      841 gattttattc agcatgtttc tttgttgttt ttcatcatca caaatacaaa tcgaagtcaa
      901 ttttttatct cctttcaaat tttatattta tatagttaag tatataatat attttgctac
      961 ctagatatat aaaatgaaat aacaattata tccagatagc aaaataaaat tttttatatt
     1021 agtatactta cacttaaaac tattctatta aacttattct gaagtgctaa tgattttctt
     1081 attaaaaaat ctaacaatct ttcttattat aaaatacaaa tgcttttatt attataaaaa
     1141 g
//
LOCUS       DAMJXI010000184         1112 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.194, whole genome shotgun sequence.
ACCESSION   DAMJXI010000184 DAMJXI010000000
VERSION     DAMJXI010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1112
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.194"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            <1..>1112
                     /locus_tag="PC465_003836"
     rRNA            <1..>1112
                     /locus_tag="PC465_003836"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          293 a          249 c          332 g          238 t
ORIGIN      
        1 ttagtagcga agtagctgat ttcacactgt caagaaaagt ctctatcgag gttaaaggta
       61 cccgtaccgc aaaccgacac aggtgggtga ggagagtatc ctaaggccag cgagagaact
      121 gttgttaagg aactcggcaa aatgaccccg taacttaggg ataaggggtg ccaccatcag
      181 gtggccgcag agaataggcc caagcgactg tttaccaaaa acataggttt ctgctaagtc
      241 gcaagacgat gtataggagc tgacgcctgc ccggtgctgg aaggttaagg ggatctgtta
      301 gagcaatcga agcagtgaac ttaagcccca gtaaacggcg gccgtaacta taacggtcct
      361 aaggtagcga aattccttgt cgggtaagtt ccgacccgca cgaaaggcgt aacgatttgg
      421 gcactgtctc aacaacagac tcggtgaaat tgtaattccg gtgaagatgc cggatacctg
      481 cgacaggacg gaaagacccc atggagcttt actgtagctt gacattgggt cttggtacta
      541 catgtacagg ataggtggga ggctttgaaa ccaggacgcc agttttggcg gagccatcct
      601 tgggatacca cccttgtagt actgggactc taaccatagg ccatgaatct ggtcttggga
      661 cactgtcagg tgggcagttt gactggggcg gtcgcctccc aaaaggtaac ggaggcgctc
      721 aaaggttctc tcagtacggt cggaaatcgt acgtagagtg taaaggcaaa agagagcttg
      781 attgcaagac atacaggtcg agcaaggatg aaaatcggac ttagtgatcc ggtggttctg
      841 cgtggaaggg ccatcgctca acggataaaa gctaccctgg ggataacagg cttatctccc
      901 ccaagagtcc acatcgacgg ggaggtttgg cacctcgatg tcggctcatc acatcctggg
      961 gctgtagtag gtcccaaggg ttgggctgtt cgcccattaa agtggtacgc gagctgggtt
     1021 cagaacgtcg tgagacagtt cggtccctat ccgtcgcagg cgtaggaaat ttgagaagac
     1081 ctgtccttag tacgagagga ccgggatgga cg
//
LOCUS       DAMJXI010000185         1078 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.195, whole genome shotgun sequence.
ACCESSION   DAMJXI010000185 DAMJXI010000000
VERSION     DAMJXI010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1078
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.195"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            216..356
                     /locus_tag="PC465_003837"
     CDS             216..356
                     /locus_tag="PC465_003837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651051.1"
                     /translation="MEKSNTTVTKKEKIEDIGMKLEHLLSEDITFYELLLEILYKEKE
                     EN"
     gene            complement(353..724)
                     /locus_tag="PC465_003838"
     CDS             complement(353..724)
                     /locus_tag="PC465_003838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2651052.1"
                     /translation="MESLGDRIANLRKELDINQKELATKVGITEASLSRYENNLREPK
                     SEIIVRLAKALETSTDYLLGVNDNTKISKEDKLIIENLSVSEKTKKLLEKIYSLEKED
                     REAIEKMIDNAYLKRFLKEEN"
BASE COUNT          409 a          111 c          131 g          427 t
ORIGIN      
        1 ctacaataat agattttttt gttattatta cgagtttttt attgcaactg tagaataaaa
       61 gtattattat ataattaaga taattatcta gggaaatttt ggataatcaa aatatatttt
      121 ataaaatcaa aatacaatta cataaacttt attaaaaatt tgttgggaat ttctgactaa
      181 cattaagaac gtaagtttgt tgggggatgg tatatgtgga aaagtcaaac actactgtta
      241 caaaaaaaga aaaaattgaa gatataggaa tgaaattaga acatttattg agtgaagata
      301 ttacttttta tgaattatta cttgagattt tgtataaaga aaaagaagag aattaattct
      361 cttctttaag gaatcttttt aaataggcat tatcaatcat tttttctata gcttctctat
      421 cttctttttc aagagaatat attttttcta agagcttttt tgttttttca cttactgata
      481 agttctctat gattaattta tcttctttgc ttatttttgt attatcattt acgcctaata
      541 aataatctgt tgatgtttct aatgcttttg ctaatctaac tattatttca cttttaggtt
      601 ctcttaaatt attttcataa cgtgacaagc tagcctcagt tataccgact ttagtagcaa
      661 gttctttttg atttatatct aattcttttc gtagatttgc tattctatct cctaaacttt
      721 ccatatgtac atcactcctt accgaaatta taagttattt tgataaaaag taaaataaaa
      781 ttaccaaaaa tataaaaaaa aaaggttaaa ataataaaat atattgaaaa ttaccatttg
      841 tatatgtata atatgaatta tacaaatggt aatttgatga gaggtggtat gttgaaataa
      901 gaaactgaat taattaataa atatatagaa agttttgaaa acccttaatt gagatataaa
      961 caatatgtac aaaatttttt gcaagtaaaa ttaccaaatg tataaaataa atcagtagca
     1021 tagataattt tatgctttaa tacattagat tatctaattt agttataatg gtcaaaaa
//
LOCUS       DAMJXI010000186         1054 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.196, whole genome shotgun sequence.
ACCESSION   DAMJXI010000186 DAMJXI010000000
VERSION     DAMJXI010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1054
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.196"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            120..872
                     /gene="cwlD"
                     /locus_tag="PC465_003839"
     CDS             120..872
                     /gene="cwlD"
                     /locus_tag="PC465_003839"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase CwlD"
                     /protein_id="HDF2651053.1"
                     /translation="MEYYGVFISIHIQGDVVRKYIKHIIFSFAMICLVVVSIFEIKNI
                     SEDVIKYMPVTNKTIILDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGL
                     VILTREDDSSLYKEENNKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYG
                     AQTFYPKDKQDSKALSKCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGF
                     LSNEKECKLLTDETYQEKIAWAIYIGIQKYLS"
BASE COUNT          467 a          110 c          162 g          315 t
ORIGIN      
        1 tagataaaca tagtgaatta aataggggca gaaatataat atcattacat aataatatat
       61 taataccaat aaataaagat atatcaatat taaaaaaatt taaatgtttg tactaatata
      121 tggaatatta tggtgttttt ataagtatac atatacaggg tgatgttgtg agaaagtaca
      181 taaaacatat aatttttagt tttgcaatga tatgtctagt agtagtatcc atatttgaaa
      241 ttaaaaatat ttctgaagat gttatcaagt atatgccagt aacaaacaaa actataattt
      301 tagatgctgg tcatggaggc attgatccag gtgcattaaa taaggataag agtacatctg
      361 aaaaggatat taacctagca ataacactta agcttagaga gcttatagaa tcaagtggtg
      421 gccttgtaat attaactcga gaagatgaca gtagccttta taaagaagaa aataataaaa
      481 ctacaagaca aaaatataat gagaatttga aaaatagaaa agaaataata tctaattcta
      541 atgccaatat gtttgtctct atacatctta atgcatttga acaatcaaaa tactatggag
      601 ctcaaacttt ttatcctaaa gacaaacaag acagtaaagc attatcgaag tgtattcaag
      661 aagaacttaa aagagtagta gataagacaa acaacagaga agtcaaacca agggatgata
      721 tatatctttt gaaagaaaat aatattccat cagtactgat agaatgtggt tttttatcaa
      781 atgaaaaaga gtgtaaactc ttaactgatg aaacatatca agaaaaaata gcatgggcaa
      841 tctacatagg aatacaaaaa tatttaagtt gaaataacta taaaaatagg tctaaatatg
      901 taaatagctt gtattaaagc agttaaaatg cattaatata ggctattttt attttgacaa
      961 aaaaatattt aaaataaaag ttaaaaagtt gttgacttag aataatatag atgatattat
     1021 atatgagtgc ccaaaaggag caccaaaata agac
//
LOCUS       DAMJXI010000187          917 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.197, whole genome shotgun sequence.
ACCESSION   DAMJXI010000187 DAMJXI010000000
VERSION     DAMJXI010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..917
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.197"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            255..761
                     /locus_tag="PC465_003840"
     CDS             255..761
                     /locus_tag="PC465_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HDF2651054.1"
                     /translation="MGFREVKIEELQFNPFTKIGKEWLLITAGDSEKFNTMTASWGGV
                     GVYWGKNVVTTYIRPQRYTKEFVDSNDTFTVAFFDETYREALNICGTISGRDINKIEK
                     AGLTPYFVDDTVAFEEANMIIVCKKLYHGNMPPENFDAKENDKKWYPEKDYHTMYISE
                     IIKVLVKE"
BASE COUNT          364 a           89 c          141 g          323 t
ORIGIN      
        1 ttactttcta cattttttta ttgtatattg ctttaggttt aaaaatatat tatatacttt
       61 ataatcaata tattttatct atattttaca cttataaaat atgaaaacta cttattgcga
      121 aagtaattga tttgttgtat tataatttac atgaattatg taggacaatc aaaagtcagt
      181 attataagag tacatatatt caaattttta acaattaatt tatataatta aaaaatgaag
      241 ggtaggatga agtcatgggt tttagagaag taaaaattga ggaattacag tttaatccat
      301 ttactaagat tggcaaagaa tggttactta taacagctgg tgattcagaa aagtttaaca
      361 caatgactgc tagctggggt ggtgttggag tctattgggg taaaaatgtt gttacaactt
      421 acataagacc acagagatat acaaaagaat ttgtagatag taatgataca tttacagttg
      481 ccttctttga tgaaacgtat agagaagctt taaatatttg tggcactatt tctggtagag
      541 atataaataa aatagaaaaa gcaggactta caccatattt tgtggatgat acggtagctt
      601 ttgaagaagc taatatgatt atagtatgta aaaagctata tcatggtaat atgccaccag
      661 aaaactttga tgctaaagaa aatgataaaa aatggtatcc agagaaagat taccatacta
      721 tgtacatttc agaaattata aaagttcttg taaaagaata attataataa aaaatatatg
      781 aaaagaactt attataagta aatgactgtg ctttcttatc tgatatctaa gtagatgcta
      841 gtaactaaat aaatattaat tttaaataaa tactattata aaaaagatga actatattta
      901 ctatagttca tcttttt
//
LOCUS       DAMJXI010000188          813 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.198, whole genome shotgun sequence.
ACCESSION   DAMJXI010000188 DAMJXI010000000
VERSION     DAMJXI010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..813
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.198"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            <1..>813
                     /locus_tag="PC465_003841"
     CDS             <1..>813
                     /locus_tag="PC465_003841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2651055.1"
                     /translation="ISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGASIVAF
                     SLTNGISPVVATLMAILCGCTAGLVTGILHIKFKISNLLSGILVMGMLYSINLRIMGK
                     SNIPLFSFKHLFNGEISPIVLALAFVFICKVLLDLFLKTGLGYTLKGVGDNSQMIKSL
                     GINIGSIKILGLMISNGLIALSGSLMAQFLGFSDVNMGIGTLVLGIASIIIGITLFKK
                     FTFIKDTTAIIVGSFIYQFTIYFAMSLGMLSTDLKLITAIVIIAFLATGNLN"
BASE COUNT          244 a          120 c          131 g          318 t
ORIGIN      
        1 ttatatctgt aatgacgcaa agtttaattt tatcgattat ggcactgggg gtttatataa
       61 cttacaaaat cttagatttt ccagatatgt ctgctgatgg tagctacaca atgggtgctt
      121 ctattgtagc attttctctt actaatggta tttctcctgt agtagcaact ttaatggcta
      181 tcttatgtgg ttgtactgct ggtcttgtta cagggattct tcacattaag tttaagatat
      241 ctaatttact ttctggtatt ttagttatgg gaatgctata ctctatcaat ttaagaataa
      301 tgggaaaatc aaatattcct ctatttagct ttaaacactt attcaatggg gaaatatctc
      361 ctatagtttt agccttagct tttgtattca tctgtaaagt ccttttagat ttattcctaa
      421 aaacaggtct tggatacact ttaaaaggtg ttggtgataa ctctcaaatg attaaatccc
      481 taggtataaa tataggttct ataaaaatac taggacttat gatttcaaat ggacttatag
      541 ctttatctgg tagtcttatg gctcagttct tgggattctc agatgtaaat atgggtatag
      601 gaactttagt tcttggaatt gcctctatca taattggtat tacactattt aagaaattta
      661 cttttatcaa agatactact gcaataattg ttggctcttt tatataccaa ttcactatat
      721 actttgcaat gagtttagga atgttatcaa ctgacttaaa actaataact gccatagtta
      781 taatagcttt cctagctact ggtaacttaa ata
//
LOCUS       DAMJXI010000189          753 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.199, whole genome shotgun sequence.
ACCESSION   DAMJXI010000189 DAMJXI010000000
VERSION     DAMJXI010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..753
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.199"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            <1..>753
                     /locus_tag="PC465_003842"
     rRNA            <1..>753
                     /locus_tag="PC465_003842"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          207 a          156 c          227 g          163 t
ORIGIN      
        1 tttaactgag cgttcagtta cttgacgtag acccgaaacc gggcgaccta cccatgagca
       61 ggatgaagcg aaagtaaaat ttcgtggagg tccgaaccca cgagcgttga aaagctcggg
      121 gatgacttgt gggtagcggt gaaattccaa tcgagcccgg agatagctgg ttctccccga
      181 aatagcttta gggctagcct caaggtgaga gatacggagg tagagcactg aatgtcctag
      241 ggggtattgc acctaccgaa gactatcaaa ctccgaatgc cgtcatctta tacttgggag
      301 tcagactgtg ggtgataaga ttcatagtcg aaagggcaac agcccagatc gtcagctaag
      361 gtccctaaat gtaagttaag tggtaaagga tgtgggattg cacagacaac caggatgttg
      421 gcttagaagc agccactcat tcaaagagtg cgtaatagct cactggtcga gtgatcctgc
      481 gccgaagatt tccggggcta aaacttacta ccgaagctac ggcatcagta atgatgggta
      541 ggggagcttc ccatacgggt tgaagcatga ccgtaaggac atgtggacag tatgggagtg
      601 agaatgttgg catgagtagc gagatgtggg tgagaatccc acaggccgta aacccaaggt
      661 ttccagggga aggttcgtcc gccctgggtt agtcgggacc taagctgagg ccgaaaggcg
      721 taggtgatgg acaacaggtt gatattcctg tac
//
LOCUS       DAMJXI010000190          737 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.200, whole genome shotgun sequence.
ACCESSION   DAMJXI010000190 DAMJXI010000000
VERSION     DAMJXI010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..737
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.200"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            <1..>737
                     /locus_tag="PC465_003843"
     CDS             <1..>737
                     /locus_tag="PC465_003843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2651056.1"
                     /translation="YIDDGWSGTNFERPSFQRMIEDIEAGKINCVVTKDLSRLGRNYI
                     MTGQYTELYFPSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKT
                     KFAEGAYYGAYAPLGYKKHPDIKGKLLVDEETKWIVEKIFSLAYQGYGSAKITKVLRE
                     EKVPTASWLNFTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNRQSTV
                     SFKSKKKVRKPESEWFRVENTHEPIID"
BASE COUNT          264 a          125 c          172 g          176 t
ORIGIN      
        1 tatattgatg acggctggtc gggaacaaat tttgaaagac cgagtttcca gagaatgatt
       61 gaagatatag aggcaggaaa aatcaactgt gttgtaacga aagacctttc ccgacttggc
      121 agaaattata ttatgacagg acaatataca gaattgtatt ttcccagcca taatgtccgt
      181 tacatagcga ttgacgacgg tgtagacagc gaaaaaggcg aaagtgagat tgcaccattt
      241 aaaaatatca ttaatgaatg ggtggcaaga gatacaagcc gtaaagtgaa atcggcattt
      301 aagacaaaat ttgcagaggg tgcgtattat ggggcttatg ctccgttagg atataagaaa
      361 caccccgaca tcaaaggaaa actgctggtt gatgaggaaa caaaatggat tgttgaaaaa
      421 atcttctccc tagcctatca aggttacggt agtgcaaaaa tcacaaaggt actgcgagaa
      481 gaaaaagttc cgacagcgtc ttggctgaat ttcacaaggt acggtacttt tgcacacatc
      541 tttgagggaa agcccgaaag caagcgttat gagtggacga ttgctcatgt caaggcaatc
      601 ttaaaaagtg aagtctatat cggaaacagc gttcataatc gacaatcaac agtttcattc
      661 aagagcaaga aaaaagtgcg taagcccgaa agtgaatggt ttcgagtaga aaatacccat
      721 gaaccgatta ttgacaa
//
LOCUS       DAMJXI010000191          737 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.201, whole genome shotgun sequence.
ACCESSION   DAMJXI010000191 DAMJXI010000000
VERSION     DAMJXI010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..737
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.201"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            <1..>737
                     /locus_tag="PC465_003844"
     CDS             <1..>737
                     /locus_tag="PC465_003844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2651057.1"
                     /translation="YIDDGWSGTNFERPSFQRMIEDIEAGKINCVVTKDLSRLGRNYI
                     MTGQYTELYFPSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKT
                     KFAEGAYYGAYAPLGYKKHPDIKGKLLVDEETKWIVEKIFSLAYQGYGSAKITKVLRE
                     EKVPTASWLNFTRYGTFAHIFEGKPDSKRYEWTIAHVKAILKSEVYIGNSVHNRQSTV
                     SFKSKKKVRKPESEWFRVENTHEPIID"
BASE COUNT          262 a          127 c          172 g          176 t
ORIGIN      
        1 tatattgatg acggctggtc gggaacaaat tttgaaagac cgagtttcca gagaatgatt
       61 gaagatatag aggcaggaaa aatcaactgt gttgtaacga aagacctttc ccgacttggc
      121 agaaattata ttatgacagg acaatataca gaattgtatt ttcccagcca taatgtccgt
      181 tacatagcga ttgacgacgg tgtagacagc gaaaaaggcg aaagtgagat tgcaccattt
      241 aagaatatca tcaatgaatg ggtggcaaga gatacaagcc gtaaagtgaa atcggcattt
      301 aagacaaaat ttgcagaggg tgcgtattat ggggcttatg ctccgttagg atataaaaaa
      361 caccccgaca tcaaaggaaa actgctggtt gatgaggaaa caaaatggat tgttgaaaaa
      421 atcttctccc tagcctatca aggttacggt agtgccaaaa tcacaaaggt actgcgagaa
      481 gaaaaagttc cgacagcgtc ttggctgaat ttcacaaggt acggtacttt tgcacacatc
      541 tttgagggaa agcccgacag caagcgttat gagtggacga ttgctcatgt taaggcaatt
      601 ttaaaaagtg aagtctatat cggaaacagc gttcataatc gacaatcaac agtttcattc
      661 aagagcaaga aaaaagtgcg taagcccgaa agtgaatggt ttcgagtaga aaatacccac
      721 gaaccgatta ttgacaa
//
LOCUS       DAMJXI010000192          712 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.202, whole genome shotgun sequence.
ACCESSION   DAMJXI010000192 DAMJXI010000000
VERSION     DAMJXI010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..712
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.202"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            97..>712
                     /locus_tag="PC465_003845"
     CDS             97..>712
                     /locus_tag="PC465_003845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF2651058.1"
                     /translation="MLNETRKKQLTEVCQDLIRNASYSGQEENVVKAIEENFALLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEARIVDGKIYGRG
                     TSDMKGQVSAMMAAVSYFAEDTNKDFEGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGINAVYKMA"
BASE COUNT          292 a           73 c          153 g          194 t
ORIGIN      
        1 aaaatcaata gattaagtga aatgctaata aattaaaaaa gtgaaatatc aaaataaaac
       61 gtcaacaaac taaaaattat atgggggaat atcaaaatgt taaatgaaac aagaaaaaaa
      121 caattaactg aagtatgcca agacttaata agaaatgcta gttattcagg tcaagaagaa
      181 aacgtagtaa aagctataga agaaaatttt gctttactag gttttgatag ttggtcaaga
      241 gatagatatg gaaatatagt aggatgtata aaaggaaata aaccaggtaa aaaaatatta
      301 tttgacgggc atatagatac agttccagtt ccagatgcaa gtaaatggag tgttcctcct
      361 tttgaagcga gaatagtaga tgggaaaata tatggtagag gaacttctga tatgaagggg
      421 caagtaagtg ctatgatggc tgctgtttca tattttgcag aagatactaa caaagacttt
      481 gaaggtgaat tgtatgtagc aggtgttgtt catgaagaaa tatttgaagg tgtttcagct
      541 agagagataa gtaaggctgt tcaacctgat tatgttgtaa taggtgaatc ttcagaatta
      601 aacctaaaga taggtcaaag aggtagagga gaaatagtag tagaaacttt tggtaaacca
      661 gctcactctg ctaatccaga aaaaggtata aatgcagttt ataaaatggc ta
//
LOCUS       DAMJXI010000193          666 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.203, whole genome shotgun sequence.
ACCESSION   DAMJXI010000193 DAMJXI010000000
VERSION     DAMJXI010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..666
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.203"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            108..578
                     /locus_tag="PC465_003846"
     CDS             108..578
                     /locus_tag="PC465_003846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HDF2651059.1"
                     /translation="MKYQVSLLAVKDIEVSKKFYKELFEQEIELDLGKNVTFKGGFAI
                     QEDFAWLTGINPDTVIQKSNNMELYFEVDDFDEFIEKLNYYKDVEFVHKPLKHEWQQR
                     VVRIYDPDKHIIEIGESMEVIARRYLSEGYSVEETSKIIQHPIEFVKQCENSKE"
BASE COUNT          288 a           55 c          123 g          200 t
ORIGIN      
        1 taaaaaagta aaaataaagg attaataaaa ggtactgaag agatagagaa aaaaatgtta
       61 atagaagata ctgaaaaaat agaaataaaa aattaggagg aaaatttatg aaatatcagg
      121 tttcattatt agcagtgaag gatattgaag tatcaaaaaa attttacaaa gaattatttg
      181 agcaagaaat tgaattggac ttaggtaaaa atgtaacatt taaaggagga tttgctatac
      241 aagaagactt cgcatggctt acagggatta atccagatac agttatacaa aaatcaaata
      301 atatggaact ttattttgag gttgatgatt ttgacgaatt tattgaaaaa ctcaattatt
      361 ataaagatgt agagtttgtc cataagccac taaaacatga atggcaacaa agagtagtgc
      421 gtatttatga cccagataag catattattg agataggaga gtctatggaa gttatagcta
      481 gaagatattt atctgaggga tattctgtag aagaaacttc taaaataatt caacatccaa
      541 ttgaatttgt aaagcagtgt gaaaatagta aggaatgatt gtttaaatta taattattta
      601 gtagaaatta attgtggtag aactaattca agataatata taggactagt atttgacaaa
      661 tgtcat
//
LOCUS       DAMJXI010000194          664 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.204, whole genome shotgun sequence.
ACCESSION   DAMJXI010000194 DAMJXI010000000
VERSION     DAMJXI010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..664
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.204"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(<1..>664)
                     /locus_tag="PC465_003847"
     rRNA            complement(<1..>664)
                     /locus_tag="PC465_003847"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          152 a          191 c          151 g          170 t
ORIGIN      
        1 gatccagccg caccttccga tacggctacc ttgttacgac ttcaccccag ttattgattc
       61 caccttcgac gacttcttcc aaaaggttag ataatcggct tcgggcgtct ccaactcccg
      121 tggtgtgacg ggcggtgtgt acaagacccg ggaacgcatt caccgcagca ttctgatctg
      181 cgattactag taactccagc ttcatgtagg cgagtttcag cctacaatcc gaactgagag
      241 tagctttaag ggattagctc caccttacgg cttggcaacc ctctgtacta cccattgtag
      301 cacgtgtgta gccctaagca taaggggcat gatgatttga cgtcatcccc accttcctcc
      361 aggttatccc tggcagtctc tctagagtgc ccaacttaat gatggcaact aaagacaagg
      421 gttgcgctcg ttgcgggact taacccaaca tctcacgaca cgagctgacg acaaccatgc
      481 accacctgtc accaatgtcc ccgaagggaa ctctccgatt aaggagatgt cattgggatg
      541 tcaagcttag gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc cgctacttgt
      601 gcgggtcccc gtcaattcct ttgagtttca ctcttgcgag cgtacttccc aggcggagta
      661 ctta
//
LOCUS       DAMJXI010000195          643 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.205, whole genome shotgun sequence.
ACCESSION   DAMJXI010000195 DAMJXI010000000
VERSION     DAMJXI010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..643
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.205"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            39..>643
                     /locus_tag="PC465_003848"
     CDS             39..>643
                     /locus_tag="PC465_003848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF2651060.1"
                     /translation="MLDAFITIVSSIIEIWSCKKVFDYTSQSKTDLKKLNMYFLFSVF
                     LIISSLYINIGANSRILICIFVMFVFYKSNYKVNIYKCLVISFFYWLILIGINGLSML
                     LVATVSNLDNMNVLLSGSLYRYEAIFLGKLMLGILLYVYKASFKNFKISKKEIYICIP
                     MIANLLSFFVLYDYIINLVKISPERRTAFLVIVLLLILSNIS"
BASE COUNT          227 a           56 c           84 g          276 t
ORIGIN      
        1 ataaaaaata taatttaatc atttttgagg atattattat gttagatgca tttataacaa
       61 ttgtttcttc tattatagaa atatggtcat gtaaaaaagt ttttgattat actagtcagt
      121 caaagaccga cttaaaaaaa ctaaatatgt attttctctt ttctgttttt ctcattattt
      181 cttctttata tataaatata ggagctaata gtagaatatt gatatgtata tttgtaatgt
      241 tcgttttcta taagtctaac tataaggtta atatatataa atgtctggta atctcatttt
      301 tttattggtt aatattaata ggtataaatg gattaagtat gttattagta gcaacagtaa
      361 gcaatttgga taatatgaat gttttactta gtggcagttt atatagatat gaagcaatat
      421 tcttgggaaa gctaatgtta ggtatattac tttatgttta taaggcttct tttaaaaatt
      481 ttaaaataag taaaaaagag atatacatat gtattcctat gatagcaaat ttattgtcat
      541 tttttgtact ttatgattat attattaatc ttgtaaaaat ctctcctgaa agaagaactg
      601 cttttttagt aatagtttta ctattaatat tatctaacat ttc
//
LOCUS       DAMJXI010000196          631 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.206, whole genome shotgun sequence.
ACCESSION   DAMJXI010000196 DAMJXI010000000
VERSION     DAMJXI010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..631
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.206"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            223..>631
                     /locus_tag="PC465_003849"
     CDS             223..>631
                     /locus_tag="PC465_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2651061.1"
                     /translation="MIFTIIFYKKGRLCLLNLQSKWVNFLKPTYVSDEIKRKKLQVII
                     FFSITYGLSYSLGLLAICFNHLIDSEILAQFMMILPLSSVSIAKFYTEGRNNDKYNFY
                     SSVILFFIIYFFIFIIESLKLISINQFQLMYLML"
BASE COUNT          257 a           48 c           74 g          252 t
ORIGIN      
        1 aaatatattg taatattaaa aaaataatag taaactgatt gcataaaaat gatttttata
       61 taaaatttaa gcagaagaat aaatttctaa cgaaattgga tatttcttct gtaaatacat
      121 attcaaaaaa agaattataa gagtttagtc agcagtcgtg taagtaataa ggactttata
      181 aatatagaaa tataatgata tgagtataag tagaaaaatt ttatgatttt tacaattatt
      241 ttttataaaa aagggaggtt atgtttgttg aatttacaat caaaatgggt aaacttttta
      301 aagccaacat atgtcagtga tgaaataaaa agaaaaaaac tacaagttat aatatttttt
      361 tctataactt atggtttatc ttattcacta ggtttattag caatatgttt taatcattta
      421 atagattcag aaattttagc tcaatttatg atgatattgc cattatcttc agtttctatt
      481 gcaaaatttt acacagaggg aagaaataat gataaatata atttttattc atcagtaata
      541 ttatttttta ttatttactt ttttatattt attattgaat cattaaagtt aataagtatt
      601 aatcaatttc aattaatgta tcttatgtta a
//
LOCUS       DAMJXI010000197          621 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.207, whole genome shotgun sequence.
ACCESSION   DAMJXI010000197 DAMJXI010000000
VERSION     DAMJXI010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..621
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.207"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
BASE COUNT          247 a           45 c           73 g          256 t
ORIGIN      
        1 tactaaaaat aagaatgtat aaggtggtaa atttatataa aaaagaatat gagttgtaaa
       61 atattaaata atattgtact aattggaata attttaactt tattatagat tattttaata
      121 ccattagtac tgatggtgta ttttaaaatt ggtataagca ttacaaatac gaatatgcca
      181 actgtaatat gtaatataag tagctatata catatgtgct gtcccatata ttgtatcatt
      241 gtttatatta aaaagattat gtaaattggt atcaatcaat aaatcatttt cagaagaaat
      301 acctaaaaac ttaaaaaata cctatatgtg tatttagtta gatttgatat ttttacattt
      361 aattttatag tgacaatatt atattatttt tatgatgtct atttatatgc aattactata
      421 atatcagaac ttatagtatc atttgtttca ttatcaataa ggttttttac tttagttttg
      481 tcaattttat taaaaaaagt tattgatata aaagataaga aggataaaac tatatgacgg
      541 atttcaaaca taagagtgga tatttatata atagatattt tatagttaat tttattagat
      601 tttatttaat actgtaatat t
//
LOCUS       DAMJXI010000198          602 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.208, whole genome shotgun sequence.
ACCESSION   DAMJXI010000198 DAMJXI010000000
VERSION     DAMJXI010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..602
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.208"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            <1..>602
                     /locus_tag="PC465_003850"
     rRNA            <1..>602
                     /locus_tag="PC465_003850"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          163 a          125 c          196 g          118 t
ORIGIN      
        1 cttgaatatc aaaggtgagc cagtacagga tggacccgcg tctgattagc tagttggtaa
       61 ggtaacggct taccaaggcg acgatcagta gccgacctga gagggtgatc ggccacattg
      121 gaactgagac acggtccaaa ctcctacggg aggcagcagt ggggaatatt gcacaatggg
      181 cgaaagcctg atgcagcaac gccgcgtgag tgatgaaggc cttcgggtcg taaaactctg
      241 tcctcaagga agataatgac ggtacttgag gaggaagccc cggctaacta cgtgccagca
      301 gccgcggtaa tacgtagggg gctagcgtta tccggattta ctgggcgtaa agggtgcgta
      361 ggcggtcttt caagtcagga gtgaaaggct acggctcaac cgtagtaagc tcttgaaact
      421 gggagacttg agtgcaggag aggagagtgg aattcctagt gtagcggtga aatgcgtaga
      481 tattaggagg aacaccagtt gcgaaggcgg ctctctggac tgtaactgac gctgaggcac
      541 gaaagcgtgg ggagcaaaca ggattagata ccctggtagt ccacgctgta aacgatgagt
      601 ac
//
LOCUS       DAMJXI010000199          529 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.209, whole genome shotgun sequence.
ACCESSION   DAMJXI010000199 DAMJXI010000000
VERSION     DAMJXI010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..529
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.209"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(<1..>529)
                     /locus_tag="PC465_003851"
     CDS             complement(<1..>529)
                     /locus_tag="PC465_003851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2651062.1"
                     /translation="YKITSLYIFKNFKIGILLFFYFLFSQIIFGLIISDNQFDYKNFL
                     NYILLPIISLVYIYPFLCEEYGWRSFLQSILFDRFGKKIGIVMVGTCWSLWHLPLQFT
                     LYSPQTPIIGAIAHLIYGIGLSIFLGYVYMKTKNIWFCSIMHVLINSLGLIFNDSEII
                     INYHSIIQRLIFILL"
BASE COUNT          234 a           69 c           53 g          173 t
ORIGIN      
        1 aataatagta taaatatcaa tctttgtata atactatggt aattaataat tatttcagaa
       61 tcattgaaaa ttaatcctaa gctattaatt agaacatgca ttatagagca aaaccatatg
      121 ttcttagttt tcatataaac ataacctaaa aatatagaaa gtccaatacc atatatcaaa
      181 tgggctatag ctccaattat tggagtttga ggactatata gtgtaaattg taaaggtaag
      241 tgccataaac tccaacaagt gcctaccatt acaataccta tttttttgcc aaatctatca
      301 aataaaatac tttgcaaaaa agatctccaa ccatactctt cacataaaaa aggataaatg
      361 tatactaatg atattatagg aagaagaata taattcaaga aattcttata atcaaattga
      421 ttatcactta ttattaatcc aaaaataatt tgagaaaata aaaagtaaaa aaatagcaaa
      481 atacctatct taaaattttt aaaaatatat aaacttgtta ttttataag
//
LOCUS       DAMJXI010000200          442 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.210, whole genome shotgun sequence.
ACCESSION   DAMJXI010000200 DAMJXI010000000
VERSION     DAMJXI010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.210"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(96..332)
                     /locus_tag="PC465_003852"
     CDS             complement(96..332)
                     /locus_tag="PC465_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651063.1"
                     /translation="MNNMENKKNFLRKIVKLRSIFLSIFGVFLFITATTGIQTVDRYV
                     PTWLYITLGVSATISLVLYVISFILKINIKDSKM"
BASE COUNT          160 a           56 c           38 g          188 t
ORIGIN      
        1 tctatttatt ttgttatttt attatttatt ttgatattaa aaaagaataa ttttgattta
       61 tcaaaattat tcttttactg gaagtttatg aagtactaca ttttactatc ttttatattt
      121 atttttaaaa taaaggaaat aacgtataaa actaatgata tagttgctga cactcccaat
      181 gttatatata accatgttgg aacatatcta tcaacagttt gaatacctgt agttgctgta
      241 ataaataaaa acacaccaaa tatgcttaga aatatgcttc ttaattttac tatttttctt
      301 aaaaaatttt tcttattttc catgttattc atatccatcc caccttttta aataatagca
      361 acaacttcca gatgtatata ataatatcag atttaatcta taaattatag tatttaatat
      421 tttatttaaa gcctagctac tg
//
LOCUS       DAMJXI010000201          391 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.211, whole genome shotgun sequence.
ACCESSION   DAMJXI010000201 DAMJXI010000000
VERSION     DAMJXI010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..391
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.211"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            154..270
                     /gene="rrf"
                     /locus_tag="PC465_003853"
     rRNA            154..270
                     /gene="rrf"
                     /locus_tag="PC465_003853"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            276..364
                     /locus_tag="PC465_003854"
     tRNA            276..364
                     /locus_tag="PC465_003854"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:310..312,aa:Leu,seq:taa)
BASE COUNT          131 a           69 c           83 g          108 t
ORIGIN      
        1 taactctata tttttaaact tgtcaaaact tatggatttt taatagtttt ataaggcaaa
       61 aaatcgaata aaaaaagtat tgacacaata agacaaagat gttattataa tacttgtctt
      121 agaaaaaaag ttaaatgaaa atttagacaa taatctggtt ataatagcag agaggataca
      181 cctgttccca ttccgaacac agaagttaag ctctctagcg ctgatggtac ttggtgggaa
      241 actgcctggg agagtaggac atagccaggt gatgtgccga agtggcggaa ctggcagacg
      301 cacaggactt aaaatcctgc gggacttacc tctcgtaccg gttcgattcc ggtcttcggc
      361 accacaaatt attgtgggcc attagctcag t
//
LOCUS       DAMJXI010000202          364 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.212, whole genome shotgun sequence.
ACCESSION   DAMJXI010000202 DAMJXI010000000
VERSION     DAMJXI010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.212"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            168..284
                     /gene="rrf"
                     /locus_tag="PC465_003855"
     rRNA            168..284
                     /gene="rrf"
                     /locus_tag="PC465_003855"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            291..362
                     /locus_tag="PC465_003856"
     tRNA            291..362
                     /locus_tag="PC465_003856"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:323..325,aa:Asn,seq:gtt)
BASE COUNT          117 a           61 c           78 g          108 t
ORIGIN      
        1 attcattaag atatatgtgc agtttttaga gtgttaactc tatgtaaagt actaacttca
       61 attgatgaag tatatatcgt aaaaacaatt actatttagt acttcaaaac tattgacatt
      121 taaaaataaa gatgttaata taatacttgt cttataaata ggcaatatgt ggttataata
      181 gcaaagagga tacacctgtt cccattccga acacagaagt taagctcttt agcgctgatg
      241 gtacttggtg ggaaactgcc tgggagagta ggacgtagcc acgtgaatat tccaaggtag
      301 ctcaatggtg gagcaaccgg ctgttaaccg gtaggctgtg ggttcgagcc ccacccttgg
      361 agcc
//
LOCUS       DAMJXI010000203          317 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.213, whole genome shotgun sequence.
ACCESSION   DAMJXI010000203 DAMJXI010000000
VERSION     DAMJXI010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.213"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            <1..>317
                     /locus_tag="PC465_003857"
     CDS             <1..>317
                     /locus_tag="PC465_003857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2651064.1"
                     /translation="EQIKSRRRQTKEKATPIFAGLVKCADCGWSMRFATNKANKTPYS
                     YYACSYYGQFGKGTCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKVLNKIQKAGNAE
                     RIR"
BASE COUNT          103 a           51 c           88 g           75 t
ORIGIN      
        1 gaacagataa aatcaaggcg tagacagaca aaggaaaaag caacgccgat atttgcaggg
       61 cttgtcaagt gtgcggattg tggctggtct atgcggtttg cgacaaataa ggcaaataaa
      121 acgccataca gttattatgc ttgcagttac tacgggcagt ttggcaaagg tacttgttct
      181 atgcactata tccgttatga tgtgttgtat caagccgtat tggaacgatt gcagtattgg
      241 gctaaggcag tacagcagga cgaagaaaag gtgttgaata agatacaaaa ggctggcaat
      301 gcagagcgaa tacggga
//
LOCUS       DAMJXI010000204          315 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.214, whole genome shotgun sequence.
ACCESSION   DAMJXI010000204 DAMJXI010000000
VERSION     DAMJXI010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.214"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(<1..268)
                     /locus_tag="PC465_003858"
     rRNA            complement(<1..268)
                     /locus_tag="PC465_003858"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           77 a           82 c           53 g          103 t
ORIGIN      
        1 ggctaatccg cgttcgctcg ccgctactta cggaatcgaa tttctttctc ttccttcagg
       61 tacttagatg tttcagttcc ctgagttccc ctcattaagc tatgtattca cttaatgata
      121 cttagacatt actctaagtg agtttcctca ttcggaaatc ttcggatcaa agtttacgtg
      181 caactccccg aagcttatcg cagcttatca cgtccttcat cggctcctag tgccaaggca
      241 tccgccctgc acccttaata acttgaccag ttaaaaaggt ttgatagatt agaagctatc
      301 aacttcgata atttt
//
LOCUS       DAMJXI010000205          310 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.215, whole genome shotgun sequence.
ACCESSION   DAMJXI010000205 DAMJXI010000000
VERSION     DAMJXI010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..310
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.215"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            <1..>310
                     /locus_tag="PC465_003859"
     CDS             <1..>310
                     /locus_tag="PC465_003859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4368 domain-containing protein"
                     /protein_id="HDF2651065.1"
                     /translation="LKKAENRQNEIDRLFAKMYEDRACEKITERNFIMLSGKYQKEQI
                     ELEQQITNLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEKILIHEATT
                     N"
BASE COUNT          129 a           47 c           71 g           63 t
ORIGIN      
        1 ttgaagaaag ccgagaaccg tcaaaatgaa attgaccgct tgtttgcgaa aatgtacgaa
       61 gatagagcct gtgagaagat aacggaacga aacttcatca tgctgtcggg aaaatatcag
      121 aaagaacaga tagaactgga acagcagata accaacctaa gagaagaatt aagtaaaatg
      181 gaacaggata tgataggtgc tgaaaagtgg attgagttaa tcaaggagta ttccgtacca
      241 aaggaactga cagcaccgtt attaaatgca atgatagaaa aaatccttat tcatgaagca
      301 acaacgaatg
//
LOCUS       DAMJXI010000206          301 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.216, whole genome shotgun sequence.
ACCESSION   DAMJXI010000206 DAMJXI010000000
VERSION     DAMJXI010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.216"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            <1..68
                     /locus_tag="PC465_003860"
     CDS             <1..68
                     /locus_tag="PC465_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
                     /protein_id="HDF2651066.1"
                     /translation="GKTMGELLTDVMLEKAKQTIA"
BASE COUNT          117 a           46 c           67 g           71 t
ORIGIN      
        1 agggaaagac aatgggagaa cttctgacag atgttatgct ggaaaaagca aagcagacaa
       61 tcgcataaaa tcggtgcagt tgtaagaaat agattgaatg acaaaaagta cccgtgttat
      121 actttacttg caagcaggta ttgtaaacac gggttagtta taaaggagga taactgacaa
      181 tgaaacaaca gatttacaat actgcacttt atcttaggtt aagccgagat gatgaattac
      241 agggcgaaag ttccagcatt accacacaaa gaagtatgtt gcgtctatat gcaaaagaac
      301 a
//
LOCUS       DAMJXI010000207          257 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.denovo.217, whole genome shotgun sequence.
ACCESSION   DAMJXI010000207 DAMJXI010000000
VERSION     DAMJXI010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..257
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.denovo.217"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            <1..>257
                     /gene="tuf"
                     /locus_tag="PC465_003861"
     CDS             <1..>257
                     /gene="tuf"
                     /locus_tag="PC465_003861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011793521.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDF2651067.1"
                     /translation="MITGAAQMDGAILVCSATDGPMPQTREHILLSRQVGVPYIVVFL
                     NKCDMVDDEELLELVEMEVRDLLTEYDFPGDDTPIVRGSAL"
BASE COUNT          101 a           34 c           57 g           65 t
ORIGIN      
        1 atgataacag gagcagcaca aatggacgga gcaatattag tttgttcagc aacagatgga
       61 ccaatgccac aaacaagaga gcatatacta ttatcaagac aagttggagt accatatata
      121 gtagtattct taaacaaatg tgacatggta gatgatgaag agttattaga gttagtagag
      181 atggaagtaa gagatttatt aacagaatat gatttcccag gagatgacac tccaatagta
      241 agaggttcag cattaat
//
LOCUS       DAMJXI010000208        56113 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.guided.018, whole genome shotgun sequence.
ACCESSION   DAMJXI010000208 DAMJXI010000000
VERSION     DAMJXI010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 56113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56113
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.guided.018"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            <1..128
                     /locus_tag="PC465_003862"
     CDS             <1..128
                     /locus_tag="PC465_003862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651068.1"
                     /translation="TLLLLLYRTSVKSQGIKQLMAGGGIVLIGIKLIPLLANALK"
     gene            139..1002
                     /locus_tag="PC465_003863"
     CDS             139..1002
                     /locus_tag="PC465_003863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651069.1"
                     /translation="MFGIFDKLTEFFKDMLLGGIKANLESMFLDINDKVGVIATDVGK
                     TPMGWNGEVYNFIKKINDNVIVPIAGLIITAVLCIELINMVMQKNNMHDTDTFEFFKY
                     IIKMFIAVYLASHAFEFSMAVFDVAQNLVNKAAGVITTSATVSGDQIVAMVDTLKEKD
                     VGALIMILVETSLVRIAIQCISLTITLIVYGRMFEIYVYSSVSSIPFATMGNKEWGQI
                     GTNYIKGLFALGLQGLFLMVCLGIYTVLIRTVQVTDIHASLFSILGYALLLGLMMFKS
                     GTVAKSIMNTH"
     gene            1012..1302
                     /locus_tag="PC465_003864"
     CDS             1012..1302
                     /locus_tag="PC465_003864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651070.1"
                     /translation="MLKKKNCALLGLGILLGGTYEILKEKKRNEEIRNLKRRINRLGR
                     CHNEFVMYQGEYNDRNEEKQEELEERISYLEEETTSNYDHILELSKKEVEGD"
     gene            1304..1714
                     /locus_tag="PC465_003865"
     CDS             1304..1714
                     /locus_tag="PC465_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012797153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HDF2651071.1"
                     /translation="MAYVPIPKDLDKIKTKVAFNLTKRQLIGFSVAGVIGIPTYLFMK
                     KYLPNDVSIIVMLIVTLPIFFITLYEKDTLTFEKYFKFFYLHKFYQPTKRIRKEAYLE
                     AKKKANQRLKSKGKTIKKRPKGSKKAKNKERSNK"
     gene            1605..4028
                     /locus_tag="PC465_003866"
     CDS             1605..4028
                     /locus_tag="PC465_003866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002836672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2651072.1"
                     /translation="MKQRKKQISDLNLREKQLKKDRKEVRRLKTKKDPTNSLLSVILK
                     KEKKRFTVEDTIPYIRMLPEGICQLDEKNYSKTISFQDINYQLALEEDRDLIFNQFAN
                     FLNSFDPSVHIELSYVNQLGRNRELQDAIKIADKGDFYDDVRKEFREMLKLQLAKGNN
                     GLKKMKYITFTTEADNLEQARAKLNRLEVDILSNFKSMGVRAESLDGEERLRLVHDML
                     NPDKNFDFSYKDLKKKESTKSHITPNIFNFAPANNFKFGKFIGAVSHFQILASELSDR
                     MLSEFLDIDDNIYVAFHIDVVEQAEAIKLIKRKNTDLDRMKIEEQKKAVRAGYDMDII
                     PSDINTFGADVKSMLSDLQNRDERLFVVTIVMMNFARTNQKLENTIAQISSIANRHNC
                     QVKRLSHQQEQGLVSVLPLGVNQVEIKRFLTSSSTAVFMPFTTEELFIDSANSLYYGL
                     NALSQNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMANAILVTDDDVIICDPEGEY
                     SNLVKQFNGEVIKVSAKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGSGL
                     TAAEKSVIDRCLPKIYQKYFEDPKPENMPILGDLYYMLLSQEEGVGRKLATEMEIYVK
                     GSLNVFNNRSNVDLNRQLLCFDIKELGTQLKKIGMLVIQDQVWNKVSLNRGNKSTRYY
                     IDEFHLLLKDPQTASYSVEIWKRFRKWGGIPTGITQNVKDLLTSQEIENIFDNTDFVL
                     MLNQASGDRDILAKKLKISPYQLNYITNSNAGEGLLFFGNTIVPFIDKFPKDTMLYKL
                     MTTKPEEAK"
     gene            4036..6615
                     /locus_tag="PC465_003867"
     CDS             4036..6615
                     /locus_tag="PC465_003867"
                     /inference="COORDINATES: protein motif:HMM:NF013073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2651073.1"
                     /translation="MDKKLKKDFQKKIIRNRDAPEKNIDSKLVHSDDYTNKIIKTKDR
                     FGDKISEKESKLIHENVLAKDQKQDKLKDFQKAKNKERIRKEVLDNKDKAGETKQTNL
                     EMRTDESFKLDEDLDVDFKKVNFDSENSRNINSNKLTTDDISAKAQPISNKKASSKRQ
                     VLKNYEDKLIHSKDKFQDKINEKESKRIHTSEDKPIEAKKSKRIYRKDKLVKDEVSKN
                     ESNTNINKKQKQKLYQEKKFRDKEKISKEIDKENKLSEVDTDKTFDNSELKDNNKEFI
                     KDEKETSLKPSEQKKVNKKKTYYKRKNYESDKFTRKKIDDLKNESKKVTRKDSKKAQD
                     VKDFISDKKIGELEKSKSKLKDNILKNKTKGSLSSGVLLSGAKSSELVRDYLSSGSDN
                     TGVESGEKAANVSSKLQHGIRKYKLDKKKKSLKKLSKLDKKIRKRKSKLEFKSGLEDL
                     KKSESYIKKNRFKKFYQRKQMKSMIAKKHETRLVDRVKKAILSLGKASKELIVRKSKM
                     VLFLVIGLGLMLSIMIGGGSVGMSGLSNSVNSVMTTTYLSQDTILSEVNQEFSSMEYD
                     LQSQIESVKTSHPGYDEYIINKEGEIGHNTHELLSYITSRCGEVKSASEVKGILKDLF
                     DKMYKLDFKEEIEIRTRTVARTRYDSRGNPYTSYEKEEYEYKKLIVTLKKKEMDEVVR
                     EIFKDYPDNVVHYEALLEAKGNMGDVFGSGNWDLGEIVDNPNFGNPGLAFDSATAKAL
                     FNEAEKHIGKRYVFGASGPSNFDCSGFVCWSFTKSGVKRMPRTTAWRIYKDYCNPVSP
                     SEAQPGDIIFFHSTYNSGTPISHVGIYAGNGMMIHAGDPIQYTSINSKYWKSHFYGFG
                     RPR"
     gene            6630..6869
                     /locus_tag="PC465_003868"
     CDS             6630..6869
                     /locus_tag="PC465_003868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001080402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651074.1"
                     /translation="MNRKLISIRNKKKKIEEKLKDLNAKYKEICDEEIQVENEEIIVT
                     LRRNNISLEELMEKINDRKREEKLKEKENIHNEEI"
     gene            6856..9207
                     /locus_tag="PC465_003869"
     CDS             6856..9207
                     /locus_tag="PC465_003869"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019450.1,HMM:NF024702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat protein"
                     /protein_id="HDF2651075.1"
                     /translation="MKKFNTNRLRAFFMALLLVLTSTVHTSAFAKSDVTWTEDDFMYS
                     SEGNIIAFSDKGLEKKEKTNILVFPEGTKSINGNYSLSHSNDELRYKREFGRGKHWDK
                     VIIPDSVKHLGYAAFYEASIDQVKLSNSLTYLGGLAFFNCGLREVTLPDTLVNIEHNA
                     FERNNLQEIIIPKSVKTIEQYAFSRNKLHTIKVLGNPNINSKGVFHNQDVEYRPKQNP
                     FYENHFGFNGNQGFKSIPNGLRFENGEFVFDKNVDSVELEFDYNNDMYQGKMTIYNPN
                     KYSVDTQTDLTGQDIDEKDNKIDDLTKNIKDLENQIKDLNDKKQEDQSKIDELKAKLE
                     SCKDNGEKLKQEKAKLEEEIRDKDNKIAQLNKEIEELKNSNNDELIAEITQLKDELKR
                     LQDENAKLKEDYSSTKWELEAEKEKTDKNENKVKEMQEKLESLEGELAKKTKEIEDKD
                     NKIKGLEKALDEKDNKIKDLESKRKETENSKSECCKKIEELQKAIDSLKESSENTKKE
                     LEEKIKGLEEKQKAYEEEIKKLKEELDKKIEEAKKLIEEANKKAKEELEKQTKDDKDK
                     NLNQDLSKKLDELLKLQKENKEKKEDKKSQDKKWDELLKADDKNILNQFDLNKMKKQE
                     EQQNKKQVKDEKEFAVFQVDKNFYNIINKDGKTTVYMDVKTYVDQGRTMIPVRYIAYT
                     LGFNVEYDNSTREAIFSNKENNILAKKTLRLNIDTGVMKDSDGKVYNSDVKPVIINGR
                     IHASISNIAKAFGASHGDIKDGKNQTIEWDNARKAVYVFKNVK"
     gene            9222..10085
                     /locus_tag="PC465_003870"
     CDS             9222..10085
                     /locus_tag="PC465_003870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HDF2651076.1"
                     /translation="MNKSIKRGVAIALLLFTFTVPATTFAMTNEGQIESQNESIYEPQ
                     KEEFEKMLKDDVFTPSKEEIPYQDVPRIPGNTSEATKPSNNPPKKTPLVKGGNTKAVN
                     SLATQENKARGSVIENVDRNGKDITPSGDTEKDKENPVDVRQFLTFQTKSGKTMHLIV
                     DHSSNQDNVRLLTEVGEQDLLNMIESEDKNTIKVEEPKKEEVKKEEPAVVPVKEEKKS
                     GIGSFLIVALVIGGVIGAGYYFKVVKAKEDKMLEDFEEDDEYISESEDESDNEESHEE
                     SLDEDDEDELL"
     gene            10149..11870
                     /locus_tag="PC465_003871"
     CDS             10149..11870
                     /locus_tag="PC465_003871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HDF2651077.1"
                     /translation="MKLVIAEKPSVAVTIAKVIGSRTRKNGYYEGNGYIVSWCVGHLI
                     QMASPERHDEKWKKWSIENLPIIPEEYIYEVSKSTKKQYGILKKLLNDKNIDTVINAC
                     DAGREGELIFRLVYNQAKCKKKIKRLWISSMENKAIEDGFRNLKEGENFEDLYRSASA
                     RAIADWLVGMNLSRLYSCIYKETYSVGRVQTPTLYLIAKRDSEINLFKKKKYYTVDLS
                     YKGLKLVSDRIDRIEVAEQLLNLLEDEIVITEVEDKEISTKPDKPYDLTTLQREANKY
                     FGYSANDTLNLAQALYEKKLITYPRTDSRYLTDDMVTTMKELLEGLEEDFKINESNFK
                     SIFNSSKVTDHYAIIPTISGIGKAKDLTDKESKIYNLIKDKLLASCSDNLKESSRKIR
                     YEYDKFNFNASGKTIIDEGYTKYLKSYGKEKQKNELPDIKTGDKIKLTSKNISEKFTK
                     APSHYNEDTLLKTMENAGVESLDKAIEVERKGLGTPATRAGIIENLIHKDLIRRDKKN
                     LLVTEKGNRLVSIVEDKFKSAETTSEWEMKLAKISSGEVDKEDFLREIEDSIKELVDR
                     YKNNLNE"
     gene            11863..12813
                     /gene="dcm"
                     /locus_tag="PC465_003872"
     CDS             11863..12813
                     /gene="dcm"
                     /locus_tag="PC465_003872"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002836657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HDF2651078.1"
                     /translation="MNKVKILELFGGIGAIRKAFINLKIPYEVVDYVEIDKACVKSYN
                     ALYGEDYKAKSVVGYKAPNEKIDLVMHGSPCQDFSRIGKKQGGAKNSGTRSSLLFETI
                     RIIKEMKDKPKWIIWENVKGVLDRNMRDSFFIYLKELESLGYESKYKILNAMDFGIPQ
                     KRERIFVVSCLGANNFSFNKLERKETRPLSEFFEKDVSELYTMTQPYMLKFLNKGIDN
                     SFRGRLKVIKDFSYTISTKQMRVPNSGIIDIGNGQYRYLTERECLRLMGFDDSDINKL
                     EEAHPRRKNCTSSKLYKQAGNSIVVDILMAIIKEIHRMEV"
     gene            17309..18319
                     /locus_tag="PC465_003873"
                     /pseudo
     CDS             17309..18319
                     /locus_tag="PC465_003873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989360.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            18391..20514
                     /locus_tag="PC465_003874"
     CDS             18391..20514
                     /locus_tag="PC465_003874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004611674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2651079.1"
                     /translation="MSRTSRITALYERLSRDDDLTGESNSITNQKKYLEDYARRNGFE
                     NIRHFTDDGFSGVNFNRPGFQSLIKEVEAGNVETLIVKDMSRLGRNYLQVGFYTEVLF
                     PQKNVRFLAINNSIDSNNASDNDFAPFLNIMNEWYAKDTSNKIKAIFDARMKDGKRCS
                     GSIPYGYNRLPSDKQTLVVDPVASEVVKRIFTLANDGKSTRAIAEILTEEKVLTPAAY
                     AKEYHPEQYNGNKFTNPYLWAMSTIRNILGRQEYLGHTVLRKSVSTNFKLHKRKSTDE
                     EEQYVFPNTHEPIISQELWDSVQKRRSRVNRASAWGTHSNRLSGYLYCADCGRRMTLQ
                     THYSKKDGSVQYSYRCGGYASRVNSCTSHSISTDNVEALILSSVKRFSRFVLNDEQAF
                     ALELQSLWNEKQEEKPKHNQSELQRCQKRYDELSTLVRGLYENLMSGLLPERQYKQLM
                     KQYDDEQAELETKMETMKTELAEEKVSSVDIKHFISLIRKCKNPTEISDTMFNELVDK
                     IVVYEAEGVGKARTQKVDIYFNYVGQVDIAYTEEELAEIETQKEQEEQQRLARQRKRE
                     KAYREKRKAQKIAENGGEIVKTKVCPHCNKEFIPTSNRQVFCSKECCYQARQDKKKTD
                     REAERGNHYYRQRVCAVCGNSYWPTHSQQKFCSEECQRVNHNKKTLEFYHHKKEKEKL
                     QCKDLSQTKERVSDMNLSGTITTPA"
     gene            20439..20810
                     /locus_tag="PC465_003875"
     CDS             20439..20810
                     /locus_tag="PC465_003875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HDF2651080.1"
                     /translation="MQRFITDERTGIRYELIGDYYYPCLTAEEKPLLSRYGRMRERYL
                     KEHKRVLYYTLMTSGKLYEHLAEIDTSACDMAEYLIKEMARKQGVTEQLKAVDMMRWI
                     GLMNNIRACVDEIVLNDIVYS"
     gene            20992..21615
                     /locus_tag="PC465_003876"
     CDS             20992..21615
                     /locus_tag="PC465_003876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-11 chloramphenicol O-acetyltransferase
                     CatP"
                     /protein_id="HDF2651081.1"
                     /translation="MVFEKIDKNSWNRKEYFDHYFASVPCTYSMTVKVDITQIKEKGM
                     KLYPAMLYYIAMIVNRHSEFRTAINQDGELGIYDEMIPSYTIFHNDTETFSSLWTECK
                     SDFKSFLADYESDTQRYGNNHRMEGKPNAPENIFNVSMIPWSTFDGFNLNLQKGYDYL
                     IPIFTMGKYYKEDNKIILPLAIQVHHAVCDGFHICRFVNELQELINS"
     gene            21864..22886
                     /locus_tag="PC465_003877"
     CDS             21864..22886
                     /locus_tag="PC465_003877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2651082.1"
                     /translation="MKLNENEMNFSVPLEIIKASEIEPKEVKWLWYPYIPFGKVTLLQ
                     GDPGDGKSKLMLSIAALLSKGEPIPFTETEENEPMTIIYQTTEDDADDTVVPRFNSAG
                     GDGENLIFIKEDEKTLSFGDNRIREAIEKYNAKLLILDPLSSYIGENCSMNNANETRA
                     EFNHLIAVAKDTGCAIVIIAHMNKMKDNNPLYRTNGSIDIAGAARSILAITRTPNKEA
                     PAERYLVQVKSNLAPTGSAILFEVAEKGVNFISEMEMTAEEAFLSLAPQIGRPNEKEM
                     KAKSFLIEMLQGGEMLSSDCEEKLEAAGFKKSTIKKAKKNAGVISKKKGFLWYWSLPM
                     SDIPRE"
     gene            23067..24332
                     /locus_tag="PC465_003878"
     CDS             23067..24332
                     /locus_tag="PC465_003878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004611677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HDF2651083.1"
                     /translation="MAKNNKADMSCARVKKYTASDVSKAERHNERKNETYENMNVIEE
                     RIPYNVHFKKPFAPTYMEQLKQMETDGMVSLRGLRKDATLFNEIVIDVNTMYFERNGG
                     YEYAKQFYEEAFHFIEEKFGADNVISAVMHADEINVAATEELGKEVYHYHLHAMVLPV
                     VEKEILWSKRCKDEKLRGTVKEVVHQISHSKKWKSDIPLTDEKGNPLLRKNGKPMFRA
                     SYSILQDELFNHMTEQGFKGFQRGEYGSTAEHLTSLQYQIKQDKERLEKLQKRIQREQ
                     IKYEPARNVSKTYNEIDRMGQKTITGKMAISKEDYSELTALAKEGITSRAEISELEQS
                     ANYYRQKYFDSANALERMKTKYDELKEKCRPFLQALEHFPEVAKLFTEKVKQLFSFKE
                     AQERAEKEAREKERQERIKARRNKRGMER"
     gene            24452..24640
                     /locus_tag="PC465_003879"
     CDS             24452..24640
                     /locus_tag="PC465_003879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004611678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2651084.1"
                     /translation="MKEQKHSYSQCIGKTTFIVNVKQSESAKKPLNTVFQDICKHEVL
                     GDFFTDKSFNLENPQKVS"
     gene            24642..25430
                     /locus_tag="PC465_003880"
                     /pseudo
     CDS             24642..25430
                     /locus_tag="PC465_003880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989360.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
     gene            26007..27677
                     /gene="ltrA"
                     /locus_tag="PC465_003881"
     CDS             26007..27677
                     /gene="ltrA"
                     /locus_tag="PC465_003881"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019034340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HDF2651085.1"
                     /translation="MNSKMCATTNRAKNWESIDFSLAESYVKKLQMRIVKAWKMSKYG
                     KVKSLQHLLTTSFYAKALAIKRVTENQGKKTSGVDGELWLTPQAKYKAIEKLNLRGYK
                     PKPLKRVYIPKKNGKKRPLSIPTMTDRAMQTLYKFALEPIAETTADPNSYGFRAKRCT
                     QDAIEQCFTSLNKKKSAKWVLEGDIKGCFDNISHEWIMNNIPMNKSLLKLWLECGYIE
                     KQRLFPTETGSPQGSPISPVISNMVLDGLEKAIKEKYHKRTVNKKAYFPKVNFVRYAD
                     DFIVTGESAELLENGVKPIIVKFLEERGLELSEEKTLITHINDGFDFLGVNIRMYKDK
                     LLTKPSEKNFKAIVDKIRQIIKDNPSMKQEILIRKLNPIIIGWINYQKYNVSSKAFEK
                     LDYEIYKCLWNWCVRRHPKKSRKWIAKKYFHTIGNRTWTFSVATGDRMENGEKYYLRL
                     KYATDTDIKRFTKIQAEANPFDENWQIYFEEREELKIRNELKGRTVINRLYKTQNGIC
                     PVCGEKITLDTDFRVHQTTQNNITLKTLVHPWCHRKLHINDKENTLAL"
     gene            27811..29139
                     /locus_tag="PC465_003882"
     CDS             27811..29139
                     /locus_tag="PC465_003882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HDF2651086.1"
                     /translation="MTSKTPVRVAEDVDEASLSYSEIKALATGNPLIKEKMDLDNEVT
                     KLKMLEANYKSNKYKLEDKVNKIYPQSILKTEMEIQAVKEDIASVEKLGEGDSKFTSI
                     SLGANKILDKKEAGEKLLEEIKKVKINDSKVIGKYRNLDLQVSYNFMTNNHTFKLLGK
                     AEYFGEFSNSTDGNITRLDNAIEKMPSRLERLNQNLENYEESLENAKVELTKPFEKAD
                     ELRDKTLRLAEINKLLDMGEVEELENQSPLLEDLKRAIVDYTNYEFSESNSYEDFDKL
                     YPDLSHIGLAYTETPDGKHSIQYEVNLEEKTWSQYVDDVAIRTESFVEEDMSNSQAIK
                     DMTEAIKMSSFDDLVSVDEEDLKQALGLEIDDDGNFYDPLAKDLDNDGIPDRYDNDFK
                     DSDYFESTYDVEDNLHAREEKPSILGQISKFKSEGEKDKNQEKNEKGQER"
     gene            29183..29839
                     /locus_tag="PC465_003883"
     CDS             29183..29839
                     /locus_tag="PC465_003883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF2651087.1"
                     /translation="MEYKDIRENLEEMMNDNYKDFIKAIVSIEKGINDEKALEEVYVL
                     YMNNDTTGLLSDDFDYMIDDMKEQGKIVENVSDIEEKDDLINLVGNIAGKVENLEREN
                     ANGEKFKVSNFSIVSKDDDGNKIYTNCSAYGDKTKDIENLKQGDFVKIFGQVKTSIDN
                     NGKEHKNVRILSSKLLKAKEQVKSQDKDKKSILGQIKSFKTDDKAKSNKKDHSKGTER
                     "
     gene            30397..31023
                     /locus_tag="PC465_003884"
     CDS             30397..31023
                     /locus_tag="PC465_003884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006309255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2651088.1"
                     /translation="MIIYSKFNNLKPEKQKQIINAAIKEFVRNGFEKASTNEIVKRAN
                     ISKGSLFNYFNSKKDLYLYLIEYSSKAIVNLNEEIDLSETDLFKRIERVALQKFYVQQ
                     KYPQAFEFLASTKQEESVEVKDIIKQRLNPIYNQAINKLYKDIDYSKFREGVDIEKAI
                     EILNWTMFGVGEKGLKELFTFDDIGRFGEKYLEEWNVYAELLKYSFYK"
     gene            31108..31989
                     /locus_tag="PC465_003885"
     CDS             31108..31989
                     /locus_tag="PC465_003885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000129978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2651089.1"
                     /translation="MTDIVKVQGLQKKFGKFQALRDVSFTIKSGEVVGFIGPNGAGKS
                     TTIRALLGIIKRDAGIAEIFGKDVWKDSLEIHKRISYVPGDVALWGSLTGGEIIDLFI
                     KLHGSGDKEKRDYLIKRFELDPKKKAKGYSKGNRQKVGLIAALSVDSDLYIFDEPTSG
                     LDPLMEQVFQEEVEKIKASGKAILLSSHILSEVERLADKVVIIRQGEIVETGTLDELR
                     HLTRSTVTLVTSGDVSKMAFVDGVHDFVQNDSQATFSVDNQYLNSILIEASKLGVTRF
                     ESIPPTLEDLFMRHYES"
     gene            31979..33628
                     /locus_tag="PC465_003886"
     CDS             31979..33628
                     /locus_tag="PC465_003886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000644977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HDF2651090.1"
                     /translation="MKAKPWEGGKIIMKEKFARWNILFLQYLKRDWKKIIIWVLGLGM
                     FSAGFVPAFKEIAKGQGLVGMFETLQNPAMISMVGPTPVETGADYTLGAMYAHEMLLF
                     CGLFAMIMSILHVIGHTRKEEDLGLTELLRSFQIGRQANSLAAIAEIVFINGILALFI
                     AVVMISFGADTISIFGSVLYGASIGMAGIIGAGIALIMAQIMPTSSAATGSSLGIVGL
                     LYIVRAGTDVSNVDLSMMNPLGWTYLTFPFTDNNWFPLIFALIFSIIVVFIAFSLEGG
                     RDMGAGYLPQREGRESAKQSLLSVRGLFININKGVIISWLIAYVVMGAAYGSIYGDMQ
                     TFLESNEMMKQMFSHTGFSIEESFTGTVMMVLIGLVSILPIAIVNKLFSEERRLHLSQ
                     IYATKVTRSQLYWTSIGLSILSGLLGVLLAAGSLGGTAISAMGNSGEMDIVDFFAAGF
                     NLFPTVLFFIGLAALALGWAPKLGKIVYIYLTFSFLLNYFSGLIDLPEWFLNTAIQSW
                     MPQMPMDDFEASVFLTVTIISIALIVIGFLGYSRRDMNEGA"
     gene            34173..34304
                     /locus_tag="PC465_003887"
     CDS             34173..34304
                     /locus_tag="PC465_003887"
                     /inference="COORDINATES: protein motif:HMM:NF033690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="erythromycin resistance leader peptide"
                     /protein_id="HDF2651091.1"
                     /translation="MYMYCSSRYYFISFIMKKIKGGKGMGMFSIFVIERFNYQSNQK"
     gene            34362..35093
                     /gene="erm(A)"
                     /locus_tag="PC465_003888"
     CDS             34362..35093
                     /gene="erm(A)"
                     /locus_tag="PC465_003888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000810833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(A)"
                     /protein_id="HDF2651092.1"
                     /translation="MKQKNPKNTQNFITSKKHVKEILKYTNINKQDKIIEIGSGKGHF
                     TKELVEMSQRVNAIEIDEGLCHATKKAVEPFQNIKVIHEDILKFSFPKNTDYKIFGNI
                     PYNISTDIVKKIAFDSQAKYSYLIVERGFAKRLQNTQRALGLLLMVEMDIKILKKVPR
                     AYFHPKPNVDSVLIVLERHKPFILKKDYKKYRFFVYKWVNREYHVLFTKNQLRQVLKH
                     ANVTDLDKLSNEQFLSVFNSYKLFQ"
     gene            35310..35834
                     /locus_tag="PC465_003889"
     CDS             35310..35834
                     /locus_tag="PC465_003889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HDF2651093.1"
                     /translation="MQLIREDFSLPFLKQLKQVLRKECASLPMDLKCLLGAHIKPLEQ
                     SIDRVEGLSEILRRSNPKMALCHTDIHNWNLMQRDEQLVLIDWEGLKLAPVKADLMFF
                     VDKPYYDVFMNIYLKLHKDFLINTDALLFYHIRRKLEDIWEFIEQLLYDNQEDKERNE
                     TIKVLDGELNNLVF"
     gene            35880..36269
                     /locus_tag="PC465_003890"
     CDS             35880..36269
                     /locus_tag="PC465_003890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019117958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDF2651094.1"
                     /translation="MNKQELYQIAFSIINHKKLRNFGTSGHVACALETNSGNIFTGIC
                     IDLPCSIGLCAEQSAIAEMVKNNETAIKRIIAVFEDGSILPPCGRCREFIAQIDNQNI
                     ETQIVLPEMEEVLLKDLLPERWDGKWN"
     gene            36260..36952
                     /locus_tag="PC465_003891"
     CDS             36260..36952
                     /locus_tag="PC465_003891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019108018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2651095.1"
                     /translation="MELKKITSRVFYYPHQPETDRPMLAYLNGDKIALAIDAGNSADH
                     VDEFYKSLEIENLKKPDFTVITHWHWDHTFGMHKIHGLSIAHHKTNEFLKQERAKLSD
                     SAYIKFLINDDECLAREYVDNKRIIAVLSDIQFEKELTLNLGGITAMIFHTVSPHSED
                     TVLIYIPEEKILFLGDSTSEDFYNDGYMDKEKLMSLTNLIESFDCKYCILSHAEPLTK
                     SDLLDYLKSILK"
     gene            complement(37838..39169)
                     /locus_tag="PC465_003892"
     CDS             complement(37838..39169)
                     /locus_tag="PC465_003892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDF2651096.1"
                     /translation="MAITKIHPIKSTLNLAIDYITKSEKTDEKILVSSFKCHPSTAHI
                     QFMKTREDNDTKGTVLARHLIQSFLPGEVDPIKAHEIGMELCKKILKENYEFVLATHI
                     DRGHIHNHIIFNNVNYKTGKCYQSNKKSYHKIRYQSDELCKANKLSVIDKYYEAYKRK
                     YKTAGKSWYEYDQNKKGNSWKSKLQFDIDRVINKSNSWEEFLENMKSLDYEIKFGKHI
                     AFRHKDKKRFTRAKTIGEDYTEEKIKERIDLAIINKANPIKKRVGNVIDISTNEKAQS
                     SKGYEVWARKHNIKTMADSIIKLREQGINSITQLDDLIKKSADDRQDLLDKIKKFETE
                     MKSLSKDMENIYTINKYREIYKYHKKNPEDKQFEEEYYSELSVYKIAAKEILENYNKL
                     PNTKEILSKLDKLQEKKNTLMQEYSLNKEQFSDLVQYRKNYENYYGKEVER"
     gene            complement(39171..39527)
                     /gene="mobC"
                     /locus_tag="PC465_003893"
     CDS             complement(39171..39527)
                     /gene="mobC"
                     /locus_tag="PC465_003893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004026808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HDF2651097.1"
                     /translation="MDNRKRNNQLKIYLTDEEKEIFEKKMKLANCKTMSHFLRKCVLE
                     KEIYVVDLEPFRNLQWLLSNATNNINQIAKATNTTGVIYKNEIESMNKQIEKLSKEIW
                     QIHSLLLNKSKESSGD"
     gene            complement(39698..40771)
                     /locus_tag="PC465_003894"
     CDS             complement(39698..40771)
                     /locus_tag="PC465_003894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence RhuM family protein"
                     /protein_id="HDF2651098.1"
                     /translation="MSREMDKNKDENQKKKELQIRSSAAEYLTFVAANGDDQEAIEIR
                     YEDENIWLTQKMMAALYDVSVSAINQHLKKIFDDNELDENSVIKKYLITANDGKSYNT
                     KHYNLQAIIAVGFKVNNERAVQFRKWANQIVKDFTIKGWAMDDERLKNSGTKLTKDYF
                     EKLLVKIREIRLSERRFYQKITDIYATSLDYDPSAKATKRFFAAIQNKLHYAIHGKTA
                     AELIVDRANHKTKNMGLTTWEGSPDSKIHKYDVVVAKNYLNEEELNQMQRIVSSYLDM
                     AELQAERHIPMTMEDWEKRLNGFLQLWDKEILNDAGKVSAALAKKHAESEFEKYRIIQ
                     DRLYKSDFDKFLELENDTKKLEE"
     gene            complement(40764..41246)
                     /locus_tag="PC465_003895"
     CDS             complement(40764..41246)
                     /locus_tag="PC465_003895"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651099.1"
                     /translation="MGIFIAGYFLLILSGIVFYYLITTYSVKISAFLIDFIVVGLGFY
                     ISIKDKLDSKLAIPLSITVVIIYGILLVLINRKLPKVSRFLNYIIAFIGSSVALWLAL
                     DFITNTLAAFKIIGQTYHQLPITKSMMINSFIHYVIVFLISIPVFKGRMKFILGGNYE
                     "
     gene            complement(41255..41803)
                     /locus_tag="PC465_003896"
     CDS             complement(41255..41803)
                     /locus_tag="PC465_003896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004818771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HDF2651100.1"
                     /translation="MSMNRYIYDKVNRLIKKYKTRDPIELIEALNINLVYLPETKILL
                     GMYHYIQRNRFIFISSNTNFNRKTILAHELGHDQLHRDYCMSGGAFHDQTVLNPTNKF
                     ETEANIFAAHLLISDEDILDNINDQVCDYEIAGQLGVDINLLNLKISELAKMGKFNKP
                     VNVNIPQGDFLKNYRPEHDDYY"
     gene            complement(41812..42213)
                     /locus_tag="PC465_003897"
     CDS             complement(41812..42213)
                     /locus_tag="PC465_003897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2651101.1"
                     /translation="MAFADRLKDFREKEKLSQADFAKMIGISTRTLVHYEDGERYPRD
                     VEVYKKIAEVMDCDYNYLLEESDEFLNRVYNMGGKRELEKARALTEGLSSLFAGGEIS
                     DEDKDAAFEAITRAYWEAKRENKKYGRKKKD"
     gene            42408..42923
                     /locus_tag="PC465_003898"
     CDS             42408..42923
                     /locus_tag="PC465_003898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651102.1"
                     /translation="MYADSDLKFEEISSAAKLILSLYRQVTWAVDSRANFMMFESKEN
                     YGSTSESAYLYLSTFAPERVEEKFNNRVSNVMDSKLILLIIYDACVRLKVYPEYGEIY
                     HKIIYNYYISEKKITDEACMRSVSLERTVYYQRKKEAIALVGVIIWGYTLPTAISQLK
                     DGRSIEEIMNI"
     gene            43193..43603
                     /locus_tag="PC465_003899"
     CDS             43193..43603
                     /locus_tag="PC465_003899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2651103.1"
                     /translation="MDKEYYLFVEGKKVVVSKEVYLAYHSELNKEKYQMRRDRLNNCF
                     FFCSYDHDGNFEENLEDLEFDVEKIIETKEMIEEVRRAIYKLNPVERDLIESLFYKEE
                     TIREVAAKLNISHPAVIKRRNKVLEKLKEMLEDF"
     gene            44141..44278
                     /locus_tag="PC465_003900"
     CDS             44141..44278
                     /locus_tag="PC465_003900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012797125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651104.1"
                     /translation="MKAIKIYSMRVAMLCRLYDLKLINDKEYAKIKNRIENDYKKRDR
                     K"
     gene            44334..46088
                     /locus_tag="PC465_003901"
     CDS             44334..46088
                     /locus_tag="PC465_003901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007790003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2651105.1"
                     /translation="MNTKVKLIKASNTGARNRNALRLDLKRVAAYCRVSTDSKDQLES
                     YKSQVDYYTNLIKNNKNWTLAGIYADEATTGTTATKRADFMRLISDCQNGDIDMIITK
                     SISRFARNTLDTLKYVRLLKENNVGVVFEEENIDTLTMDGELLLTILSSVAQQEVENT
                     SAHVKKGLKMKMEKGELIGFQGCLGYDYDPITKSISINEEEAKIVRYIFKRYLEGNGG
                     SVIGRELEEQGYLTPRGKTKWSDTTVLGVIKNEKYIGDILMGKTFTVDPITKRRLANF
                     GESDKYHIENHHEPIISKEDFEKAQEIRLRRAQNRNTIANKDRKREKLSRQYAFSSML
                     ECGFCGEILSRRTWHTSSIYKKINWQCVKSTKKGKKYCPHSKGIQEAAIEKAFVESYR
                     QLCHADSTVIDDFLKIVEEEINDNTLVKDLKKLENQLNRIISQERKLVDLHLEDSIDE
                     EVYAKKYKKLTKQKEELLDEKKTLELTIKDEDSIKERLKQFKKVLENKEIIEEFNRTV
                     FESIVDKVVVGRIDKDGTVHPYDLTFYFKTGVKDSQDSNNFKDKRKNAKDNDINKLCS
                     YKNDEDKKLCSQSKDNAL"
     gene            46627..47661
                     /locus_tag="PC465_003902"
     CDS             46627..47661
                     /locus_tag="PC465_003902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHYH domain-containing protein"
                     /protein_id="HDF2651106.1"
                     /translation="MFKKKLIAVAMSITMISVGSFSYAHSGRTDSSGGHRDNKNKSGL
                     GSYHYHCGGYPAHLHNNGGCPYTGGGSSSGTTTSVNNEEKQKRSVGEKGYNQGYEDGY
                     KGNYSSSNYSGDYSDTYESKYSEGYEKGKAKLEEEEKVAKETGYNLGLTGAKSNNTYE
                     KEVLKNAYDTGYSTGYNEYKTKKIEEYKAKGIEDSNKDKEKMTFEENIDSEFIDAYNN
                     AYDEIQEQLKNDYTTQGFESAIKGERFDTSTIGNVKYANWFKEGYDNGKVKLPKAKES
                     VYNQGYNEEDFSIPDEMKSIETKLKGVYDEGLEKREEEKSRNATYGVGAGIAAVVAGV
                     VYKKKKRKKI"
     gene            47748..47951
                     /locus_tag="PC465_003903"
     CDS             47748..47951
                     /locus_tag="PC465_003903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4236 domain-containing protein"
                     /protein_id="HDF2651107.1"
                     /translation="MGFNFRKSINLGGGLKLNLGKKSVGISAGVKGARVSVNSKGRKS
                     ATLSIPGTGISYTKTSTKKRKPK"
     gene            48122..49009
                     /locus_tag="PC465_003904"
     CDS             48122..49009
                     /locus_tag="PC465_003904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF2651108.1"
                     /translation="MKLSKTLLAIGMSVSLLIASCPTSNALSSINSIKGTNKYETAGL
                     IADKQNYDIAILINSENGLSDGLSASGLSGAKNAPILLTKKDTIPSETLKRLEKVKEV
                     YLIGGKNSIGASVQKILSDKKISINRISGTDRIDTSHKVAKEIGRVSTVKKVILTNAF
                     KGEPDAMSVASIAVRDKSPIVLTDGNTTSFATDGLETYAIGGKVSMSDKLINETKATR
                     IGGVDRYDTNKQIINKFYNGSKEFYIASGTDLVYSLVGSTIAQKTPIVLVGNGSNKSI
                     LKNASKITAIGNIDDVVIK"
     gene            49542..49682
                     /locus_tag="PC465_003905"
     CDS             49542..49682
                     /locus_tag="PC465_003905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651109.1"
                     /translation="MENLMMSIITGVIASYIYDKLKSHSERPTKSGWELNIKFQKSKS
                     SK"
     gene            complement(50346..50666)
                     /gene="rhaM"
                     /locus_tag="PC465_003906"
     CDS             complement(50346..50666)
                     /gene="rhaM"
                     /locus_tag="PC465_003906"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HDF2651110.1"
                     /translation="MNTIRKCFKMKLFKGFENEYKKRHDELWSEMIDMIHEYGGSNYS
                     IFLDEETNYLYGYIELKDAKLWDKSSETAICKKWWNYMSDIMETNEDNSPVSIELKSM
                     FYLK"
     gene            50852..51133
                     /locus_tag="PC465_003907"
     CDS             50852..51133
                     /locus_tag="PC465_003907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651111.1"
                     /translation="MKDETLEDILKQKTQAERYILEYIVTKNVKKLDNKKIVSILHTI
                     LCWEEINGTIVLTDKNILSLDEDIIISKHRRFIDIPKHKHNFIEFHLMS"
     gene            51257..52228
                     /locus_tag="PC465_003908"
     CDS             51257..52228
                     /locus_tag="PC465_003908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2651112.1"
                     /translation="MRQYIHDKLREITEEEKNILEGNYIIDKSIYTDNSQFIIDSNKL
                     LNIDELIHIRKHTRFAQFPKHKHNYIEFNYVYRGKLVQTIDEYKINLKQGELIFLNQH
                     VIHEIEASDEEDIIINFIIKPEFFDYIISLLENDNKIMNFLMTTLYTNYNLGEYIYFK
                     VSEKEEIQDIIEKIIIELYEPSVVNKVKIKLLVGLLLVELVKNSEDVENHAVDNYEKM
                     MIIEILKYIDKDYKKGSLSEIASNLNQGDYKISKLVKKHLGYTFKDLVQEKRLSKACE
                     LLVSTNLSIAEIIENVGYENLTYFYKIFKNKYGITPKEYKKNIKNSQ"
     gene            52435..53829
                     /gene="rhaB"
                     /locus_tag="PC465_003909"
     CDS             52435..53829
                     /gene="rhaB"
                     /locus_tag="PC465_003909"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HDF2651113.1"
                     /translation="MRYYLAIDIGASSGRHIISYINNGKLEIEEVYRFKNNLIKKDGH
                     FCWDISKLFSEIKNGIKKCIKINKIPVSVAIDTWAVDFVLLDEKDNILGNCVSYRDNR
                     TDGIMEEAFKIIDKKELYLKTGIQFQKFNTIYQLLAIKNQQPDLLEKAKSFLMIPDYF
                     NFLLTGKKVTEYTNATTTQLVNTTTNNWDEEIINKLGFDKMLFAKIKTPKTILGSLKK
                     ELVEELGCDLEVILPVTHDTGSAFMSTPVKNRSILLSSGTWSLLGVELERPKCKLEAL
                     DYNFTNEGGYEYRYRFLKNIMGLWMIQEARKCYDSKHSFTELVEHARLSEGFKSIVDV
                     NDDRFLNPENMVQEIIKYCIETNQTEPQTVGEVAYCIFNSLAKSYSKSINEIEKIIEE
                     KLETISVFGGGCQNELLNELIAKESGKKVLAGPVEATALGNIVCQLIAKNELNDLEQA
                     RDIIRNSFDIIQYN"
     gene            53850..55106
                     /gene="rhaA"
                     /locus_tag="PC465_003910"
     CDS             53850..55106
                     /gene="rhaA"
                     /locus_tag="PC465_003910"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HDF2651114.1"
                     /translation="MELKQRYEVAKKEYEKWGINVEEVLRVLSKVKISIHCWQGDDVT
                     GFEGNQQRLSGGIASTGNYPGKARNPQELRRDLDKALSLIPGKHKVNLHAIYAETGGS
                     FVDRDELKPEYFENWVKWAKERGLGLDFNPTIFSHPKSSDGLTLSHPDKKIRDFWIKH
                     CIASRKIGEYFGKELGQTCLTNIWIPDGYKDIPSDRLGPRRRLKESLEEILKVEINRE
                     YNLDCVESKVFGLGVESYTVGSNEFYLNFASKNNIISLLDTGHYHPTELVSDKLSSML
                     LFSDKVALHVSRPVRWDSDHVVILDDELKEIAKEIVRNDALDKVIIGLDFFDASINRI
                     AAWVIGTRNMIKALLSAMLMPHEELRKLQDEGDFTKRLAIMEEFKTYPMGDIWNYYCK
                     INNVAVKEDWIEVVKEYELTELLNRK"
     gene            55117..55932
                     /gene="rhaD"
                     /locus_tag="PC465_003911"
     CDS             55117..55932
                     /gene="rhaD"
                     /locus_tag="PC465_003911"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HDF2651115.1"
                     /translation="MSIMEMNFIKDFMKITYDAWLKGWHERNGGNITYRLTPEEISGI
                     KEFITEEIEYIPIGVTVENLANEYFLVTGSGKFMRNISINTVQNVGIVKIDEKGENYA
                     IVWGLDKAKPTSEFPSHLMSHSIKKDKTNGLHRVIMHSHTTNLIALTFILPLEGKVFT
                     RELWEMATECPAVFPEGIGIVPWMVPGGIEIAKATQNLMEKHNIVIWAHHGTFCSGET
                     LDLTFGLMDTVEKSAEILVKVISMGGKKQTITGDNFRDLSKNFKVSISEDYLY"
BASE COUNT        21727 a         7363 c        10482 g        16541 t
ORIGIN      
        1 ttacacttct attacttctt tatcgcacat cagtaaaatc tcaaggtatt aagcagctta
       61 tggctggtgg aggaattgtg ctaatcggta tcaaattaat tccactactt gcaaatgctt
      121 taaaatagga gaaagtctat gtttggtatc tttgacaagc taacagaatt ttttaaggat
      181 atgctactcg gaggtatcaa agcaaatctt gagtccatgt tcttagatat aaatgacaag
      241 gtaggagtta ttgcaactga tgttgggaaa acaccaatgg gttggaatgg agaagtgtat
      301 aacttcataa aaaaaattaa tgataatgtg atcgttccaa tagcaggtct tatcataaca
      361 gcagtattat gtattgaact cataaatatg gttatgcaaa agaataatat gcatgataca
      421 gatacttttg agtttttcaa atatattata aagatgttta tagcagtcta ccttgcaagc
      481 catgcctttg aattttcaat ggcagtcttt gatgtggcac aaaatcttgt aaacaaagcg
      541 gcaggggtaa tcactacttc tgccactgtt tcaggagatc agatagttgc aatggttgat
      601 acattaaaag aaaaagatgt tggtgcatta ataatgatat tagttgaaac aagccttgta
      661 aggattgcaa ttcaatgtat atctttaact attaccttaa tagtatatgg gcgtatgttt
      721 gaaatatatg tctactcatc agtatcatcc ataccatttg cgactatggg aaataaagaa
      781 tggggtcaga ttggaacaaa ttatatcaag ggactttttg ccttgggact acaaggtttg
      841 tttttgatgg tatgtttagg tatctacacc gttttaataa ggacggtaca ggttacagat
      901 attcacgcaa gcttgtttag tatattagga tatgctctac tacttggact tatgatgttt
      961 aagagtggaa cagttgcaaa aagtattatg aatacgcact aggaggaata aatgttaaaa
     1021 aagaaaaatt gtgctttatt gggacttgga attttattgg gaggaactta tgaaatctta
     1081 aaagagaaaa aaagaaatga agagattaga aatttaaaga ggagaataaa cagactcgga
     1141 agatgtcaca atgaatttgt tatgtatcaa ggagaataca atgacagaaa tgaagaaaaa
     1201 caagaagaat tagaagaaag aattagctac ctagaagaag aaacaacatc taattatgac
     1261 catatacttg aactttccaa aaaagaagta gagggagatt aaaatggcgt atgtaccaat
     1321 accaaaagat ttggataaga ttaaaacaaa ggttgccttt aacttaacca aaagacaact
     1381 tataggtttt tctgtggcag gagtaattgg cataccaacc tatttattta tgaagaaata
     1441 tctacctaat gatgtttcaa tcattgtaat gctaatagta accctgccaa tcttttttat
     1501 aaccttatat gaaaaagata ccttaacttt tgaaaaatat tttaaatttt tctatcttca
     1561 taaattttat caaccaacta agagaataag aaaggaggca taccttgaag caaagaaaaa
     1621 agcaaatcag cgacttaaat ctaagggaaa aacaattaaa aaaagaccga aaggaagtaa
     1681 gaaggctaaa aacaaagaaa gatccaacaa atagtcttct aagtgtaatt ttaaagaaag
     1741 agaaaaagag atttactgtt gaggatacta ttccctatat aagaatgtta ccagagggca
     1801 tatgccagtt agatgaaaaa aattattcaa agacaatttc atttcaagat ataaattacc
     1861 agttggcatt ggaagaagat agagatttaa tctttaacca atttgccaac tttttaaatt
     1921 cttttgatcc aagtgtccac attgaacttt catatgtaaa tcaattagga aggaatagag
     1981 aactacaaga tgcaattaaa attgctgata agggagactt ctatgatgat gtaagaaaag
     2041 agtttaggga gatgttaaag cttcaacttg caaagggcaa taacggactt aaaaagatga
     2101 agtatataac ctttacaaca gaagccgaca acctagagca agcaagagcg aagttaaata
     2161 gacttgaagt agatatttta tctaacttta aatctatggg agtaagagca gagagccttg
     2221 atggcgaaga aagactaaga cttgttcacg atatgttaaa tccagacaag aactttgatt
     2281 tttcatataa agatttgaag aagaaagagt ctacaaaatc acatataact cccaatatct
     2341 ttaattttgc accagcaaat aattttaaat ttggcaaatt cattggagca gtaagtcatt
     2401 ttcaaatact tgcaagtgag ttatcagaca gaatgttatc tgagttttta gatattgatg
     2461 acaatattta tgtagctttt catatagatg tagttgaaca agcagaagct attaaactca
     2521 ttaagagaaa aaacacagat ctggacagaa tgaaaattga agaacaaaag aaagcagttc
     2581 gtgctggata tgatatggat attattcctt cagatataaa tacttttggg gctgatgtta
     2641 agtccatgtt atctgactta caaaatagag atgagaggct ctttgtagtt accattgtaa
     2701 tgatgaattt tgctagaact aatcaaaaat tagaaaatac aattgctcaa atttcatcaa
     2761 ttgcaaacag acataattgt caggtaaaaa gattatctca ccaacaagag caaggacttg
     2821 tttctgtctt acctttagga gttaaccaag tcgagataaa aagattttta acttcatcat
     2881 caacagcagt atttatgcct tttacaacag aagagctatt tattgattcg gcaaattctt
     2941 tgtactatgg attaaatgcc cttagccaaa acttgattat ggcagatagg aagaaactta
     3001 agaaccctaa cggattaata ttaggaacac caggttctgg taaatctttc tcggcaaaga
     3061 gagagatggc aaatgcaatt cttgtaacag atgacgatgt aattatttgt gatcctgaag
     3121 gcgagtattc aaaccttgta aaacaattta atggagaagt tattaaagtt tcagcaaagt
     3181 caaaggacta tctaaatcca ctagatatta atatgaacta tggagatggg gacgcacctt
     3241 taaaggataa ggcaaacttc ataatgtcta tgcttgaact tgtagtagga ggatctggtc
     3301 ttactgctgc agaaaaatct gttatagata ggtgcttacc aaagatatat caaaaatatt
     3361 ttgaagaccc aaaaccagaa aatatgccta tattaggaga tttatactat atgctcttat
     3421 ctcaagaaga gggagttggt agaaaactag caacagaaat ggaaatttat gttaagggaa
     3481 gtcttaatgt atttaataat aggtcaaatg ttgacctaaa taggcaactt ctttgctttg
     3541 atataaaaga gctgggaaca caacttaaaa aaataggtat gcttgtaatt caagaccaag
     3601 tttggaacaa ggtttccctt aatagaggaa acaagtctac aagatactat atagatgagt
     3661 tccacctttt attaaaagac ccacaaactg cttcatattc agtagaaatc tggaaaagat
     3721 ttagaaaatg gggtggtatt ccaacaggta taactcaaaa cgtaaaagac cttttaacaa
     3781 gtcaggaaat agaaaatatc tttgacaata cagactttgt tctaatgtta aatcaagcat
     3841 ctggagatag agatattctt gctaagaaat taaaaatatc gccttatcag cttaattata
     3901 taactaattc aaacgcaggt gagggactct tattcttcgg aaatactatt gttccattta
     3961 ttgataaatt ccctaaagac accatgctat ataagctaat gacaacaaaa ccagaagaag
     4021 ctaagtaggt gtgatatgga taaaaaacta aaaaaagatt ttcaaaagaa aattatacga
     4081 aatagggacg ctcctgaaaa gaatattgat agtaaacttg ttcattcaga tgattatacc
     4141 aataagataa ttaaaactaa ggataggttc ggagataaaa tttcagaaaa agaatctaaa
     4201 cttattcatg agaatgtatt agctaaagat caaaaacaag ataaactaaa agattttcag
     4261 aaggctaaaa acaaggaaag aatcagaaaa gaagttttag ataataagga taaggctgga
     4321 gaaacaaaac aaactaatct tgaaatgagg acagatgaaa gctttaaact tgatgaagac
     4381 ttagatgtag attttaaaaa ggtaaatttt gatagtgaaa acagtagaaa tattaattct
     4441 aataaactaa caacagatga tatttcagct aaggctcaac caataagcaa taagaaggca
     4501 tcaagtaaaa gacaagttct caaaaattac gaggataaac ttatccatag taaggataaa
     4561 ttccaagaca aaatcaacga gaaagagtct aagcgaattc atacaagtga agataaacct
     4621 atcgaagcaa agaaaagtaa gagaatatac agaaaagata agcttgttaa agatgaagta
     4681 agcaagaacg agagtaatac taatatcaat aaaaagcaaa agcagaagct ttatcaagaa
     4741 aagaagttta gagataagga aaaaatttct aaagagatag ataaagaaaa taagctaagc
     4801 gaagttgata cagataagac ttttgacaat tctgagctta aagacaataa taaagaattt
     4861 ataaaagatg aaaaggaaac aagccttaaa ccttcagaac aaaagaaagt taataaaaag
     4921 aagacttact ataagagaaa aaattatgaa agtgataaat tcactcgaaa gaaaatcgat
     4981 gacttaaaaa atgaatctaa gaaagttaca agaaaagatt ctaagaaggc acaagatgtt
     5041 aaagacttta tctcagataa aaagattgga gagcttgaaa agtctaaaag caagctaaag
     5101 gataatattt taaagaataa aactaaagga agtctatctt ctggggtttt attatctgga
     5161 gctaagtctt cagaattagt gagagattat ttaagttcag gatctgataa tactggtgta
     5221 gaatctggag aaaaggccgc taatgtaagc tctaaactcc agcatggaat aaggaagtat
     5281 aagttagaca aaaagaaaaa gtccttaaaa aagctatcta aacttgataa gaaaataaga
     5341 aagagaaaaa gcaagttgga atttaaaagt ggcttggaag atttaaaaaa gtcagaatca
     5401 tatataaaga aaaatagatt taagaagttt taccagagaa aacaaatgaa gagcatgata
     5461 gctaaaaagc acgaaacaag acttgtagat agagttaaaa aagctatttt aagtttaggt
     5521 aaggcttcta aagagctaat cgtaagaaaa agtaagatgg ttctatttct agtaataggg
     5581 ctaggtctta tgctatcaat catgattggt ggtggaagtg ttggtatgag tggattaagt
     5641 aactctgtta actcagtaat gacaacaaca tacctatcac aagacacaat tctaagtgaa
     5701 gtaaatcaag aattttcatc aatggaatat gacctacaat cacaaatcga aagtgtaaaa
     5761 acaagtcatc ctggatatga cgaatatatt ataaacaaag aaggagaaat tggtcataat
     5821 acccatgaac ttttatccta tataacttca agatgtggag aagtaaaatc agcatctgaa
     5881 gtaaaaggaa ttttaaaaga tcttttcgat aaaatgtata agcttgattt taaagaagaa
     5941 attgaaatta gaacaagaac agtagcaaga actagatatg atagtcgtgg caatccttat
     6001 actagctatg aaaaagaaga gtacgaatat aaaaagttaa ttgtaacttt aaagaaaaaa
     6061 gaaatggatg aagttgttag ggaaatattt aaagattatc cagacaatgt agttcattat
     6121 gaagctcttc ttgaagctaa gggaaatatg ggagatgttt ttggatcagg taattgggac
     6181 ttaggagaaa tagtagacaa tccaaacttt ggaaatcctg gtcttgcttt tgattccgct
     6241 actgccaagg ctctttttaa tgaagcagaa aaacatatag gcaaaagata tgtgtttgga
     6301 gcaagtggac catctaactt tgactgttca ggttttgtat gttggtcatt tactaagtct
     6361 ggtgtaaaga gaatgccaag aacaactgca tggaggatat acaaagacta ttgtaatcca
     6421 gtaagtccaa gtgaagccca acctggggat attatatttt tccactcaac atataacagt
     6481 ggaacaccaa tatctcacgt aggaatatac gcaggtaacg gaatgatgat tcacgcagga
     6541 gatccaattc aatacacgtc aataaattca aaatattgga aatcacattt ttatggtttt
     6601 ggaagaccaa gatagaaggg agatattatg tgaacagaaa acttataagt attaggaaca
     6661 aaaagaaaaa aatagaagag aaattaaaag atttaaatgc aaaatacaag gaaatttgcg
     6721 atgaagaaat acaagttgaa aatgaagaaa taattgtaac tcttaggagg aacaatatta
     6781 gcttggaaga attaatggag aaaatcaatg atagaaaaag agaagaaaaa ttaaaagaaa
     6841 aggagaacat tcataatgaa gaaatttaat acgaacagac taagagcctt ttttatggct
     6901 cttttattag ttttaacatc aactgtgcat acaagtgcat ttgcaaagtc tgatgttact
     6961 tggacggaag atgattttat gtattcctct gagggaaata taattgcctt tagtgataaa
     7021 ggcttagaaa agaaagagaa gacaaatatt ctagtatttc ctgaaggaac gaagtctata
     7081 aatggaaatt attctttaag tcattcaaac gatgaactta gatataaaag agaatttgga
     7141 cgtggcaaac attgggataa agtaattatt cctgattctg ttaagcattt aggttatgct
     7201 gccttttacg aagcaagtat agatcaggta aaactatcaa atagcttaac ttatcttggt
     7261 ggtttagcat ttttcaattg tggacttaga gaagtgactt tacctgatac tttggtaaat
     7321 attgaacata atgcttttga aagaaataac ctccaagaaa taattatacc gaagtctgtg
     7381 aagacaattg aacagtatgc tttttcaaga aataaattgc acactataaa agttttaggt
     7441 aatccaaata ttaacagtaa gggagttttc cataatcaag atgttgaata tagaccaaaa
     7501 caaaatccat tttacgaaaa tcattttggt ttcaacggaa atcaagggtt caaatctatt
     7561 cctaatggat taaggtttga aaatggagag tttgtctttg ataagaatgt agatagtgta
     7621 gaacttgaat ttgattataa caatgatatg tatcaaggaa agatgactat ttacaatcca
     7681 aataaatatt ccgttgatac tcaaacagat ctaacaggac aagatattga tgaaaaagat
     7741 aacaagattg atgatttaac taaaaacatt aaagatttag agaatcagat caaagactta
     7801 aatgataaga aacaagaaga ccaatcaaag atagatgaat taaaggcaaa gttagaatct
     7861 tgcaaagata atggagagaa actaaaacaa gaaaaggcta agttagaaga agagattaga
     7921 gataaagaca ataagattgc tcaattgaat aaagaaattg aggaactcaa aaattctaac
     7981 aatgatgaac taatagcaga aattactcag cttaaagatg aattaaaaag attacaagat
     8041 gaaaatgcaa aactaaaaga agattattca tctacaaaat gggagttaga agctgagaaa
     8101 gaaaagaccg ataaaaacga aaataaagtc aaagaaatgc aagaaaagct cgagtcttta
     8161 gaaggagaac ttgcaaagaa gactaaagaa attgaggata aagataataa aattaagggt
     8221 ttggaaaaag ctcttgatga aaaagataat aagataaaag accttgagtc taaaaggaaa
     8281 gagacagaaa attctaagtc agaatgctgt aagaaaattg aagagcttca aaaggctatt
     8341 gatagtttaa aagaatcttc tgaaaataca aaaaaagaat tagaagagaa aattaaagga
     8401 ctagaagaaa aacaaaaagc ttatgaagaa gaaattaaaa agttaaaaga agaattagat
     8461 aagaaaattg aagaagcaaa gaagttaatc gaggaagcaa ataaaaaagc gaaagaagaa
     8521 cttgaaaaac aaactaaaga tgataaagat aaaaatctaa atcaagacct atctaaaaaa
     8581 ttagatgaac ttctaaaact ccaaaaagaa aacaaagaaa agaaagaaga taagaaatct
     8641 caagataaga agtgggatga acttttgaaa gctgatgaca agaacattct aaatcaattt
     8701 gatcttaaca agatgaaaaa gcaagaggaa caacaaaaca aaaagcaagt taaagatgaa
     8761 aaagaatttg cagttttcca agtagataaa aacttttata acattatcaa caaagatggt
     8821 aagacaacag tctatatgga tgtaaaaact tatgtagacc aaggaagaac tatgattcca
     8881 gtaagatata ttgcttatac tctaggtttt aatgttgagt atgacaactc tactcgtgaa
     8941 gctattttct caaataaaga gaataatatc ttagctaaaa agacattaag actaaatatt
     9001 gatactggtg tcatgaaaga ttcagatgga aaagtctaca attcagatgt taagccagtg
     9061 attataaatg gaagaattca tgcttcaatt tcaaatattg ctaaagcttt cggagcaagt
     9121 catggagata ttaaagatgg taaaaaccaa acaatagaat gggacaatgc tagaaaagca
     9181 gtctatgtat ttaaaaatgt aaaataagaa aggatagaaa aatgaataag agcattaaac
     9241 gaggagtagc catagcgtta ctccttttta catttacagt accagcaact acatttgcga
     9301 tgacaaatga agggcaaata gaaagtcaaa acgaatcaat ctatgaacca caaaaagaag
     9361 aatttgaaaa aatgttgaaa gatgatgttt ttacaccatc aaaagaagag attccttatc
     9421 aagatgttcc gagaatacca ggaaatacaa gtgaagcaac caagccttca aataatcctc
     9481 ctaagaaaac accacttgta aaaggtggta atacaaaggc agtaaatagt ctagcaacac
     9541 aggaaaataa ggcaagaggt tcagtaattg aaaacgtaga taggaatgga aaagatatta
     9601 caccaagtgg agacacagaa aaagataaag aaaatccagt agatgtaaga caattcttaa
     9661 catttcaaac taaaagtgga aaaactatgc acctaatagt ggatcactca tcaaaccaag
     9721 ataatgtaag gctattgaca gaagtaggag agcaagacct acttaatatg attgagtcag
     9781 aagataaaaa cactataaag gttgaagagc ctaagaaaga agaagtaaaa aaagaagaac
     9841 ctgctgttgt tccagtaaaa gaagaaaaga aaagcgggat aggttcattt ctaattgttg
     9901 cacttgtaat tggaggagtt ataggagcag gatactattt taaggtagtt aaagcaaaag
     9961 aagataaaat gttggaagac tttgaagaag atgatgagta tattagtgag tcagaagatg
    10021 agtctgacaa tgaagaaagt catgaagaat ctttagatga agatgatgaa gatgaactat
    10081 tataataatt tttaaaagct tgagcgagag agaaatcttt cgctcttttt taatttatgg
    10141 aggtatgaat gaagttagta atagcagaaa aaccaagtgt agcagttaca attgcaaaag
    10201 taattggatc aagaacaaga aaaaacggat attatgaggg gaatggatac attgtttctt
    10261 ggtgtgtcgg tcatttaatt caaatggcaa gtccagaaag acacgatgaa aaatggaaga
    10321 aatggtcaat agaaaatctt ccaataattc cagaagaata tatttatgaa gtatctaaaa
    10381 gcactaaaaa acaatatgga attttgaaaa aacttttaaa tgataagaac atcgacacag
    10441 ttataaatgc ttgtgatgct ggtagagagg gagaacttat ttttagactt gtatataatc
    10501 aagctaaatg taagaagaag attaaaagac tttggatatc ttcaatggaa aacaaagcta
    10561 ttgaggatgg ctttagaaat cttaaagaag gggaaaactt tgaagactta tatagatcgg
    10621 caagtgcaag agctattgca gattggctgg taggaatgaa tttaagtagg ctttattctt
    10681 gcatttacaa ggaaacatat tctgttggta gagtacaaac cccaacccta tatttaatag
    10741 ctaaaaggga tagtgaaata aacctattta agaagaaaaa atattataca gttgatctat
    10801 cttataaagg attgaaactt gtatcggata ggattgatag aattgaagtt gcagagcaac
    10861 tattaaatct gctagaagat gaaatagtta ttacagaggt agaagataaa gaaataagca
    10921 caaaaccaga taagccttat gatctcacga ccttacaaag agaagcaaat aaatattttg
    10981 gatattcagc aaatgacact ttaaacctgg cacaagcttt gtatgaaaaa aagctaatca
    11041 catacccaag aacagatagt aggtatttaa ccgatgatat ggttactact atgaaagaat
    11101 tattggaagg acttgaagaa gattttaaaa tcaatgaatc aaactttaag tctattttta
    11161 attcatctaa agttacagac cactatgcaa ttattcctac tatatcaggt attggaaaag
    11221 ccaaagattt aactgataaa gaaagtaaaa tctataatct aattaaggat aaattacttg
    11281 cttcatgttc ggataactta aaggaatcta gtagaaaaat cagatatgaa tatgataaat
    11341 ttaacttcaa tgcaagtggc aagactataa tcgatgaagg ttataccaag tatctaaaga
    11401 gctatggaaa agaaaaacaa aaaaatgaat taccagatat aaagactgga gataaaatta
    11461 agctaacttc taaaaatata tcggagaaat tcaccaaagc cccaagtcat tataatgaag
    11521 atacactttt aaagactatg gagaatgcag gagtagaatc tttggataaa gctatagaag
    11581 tagaaagaaa aggcttagga acaccagcta caagagcagg aattatcgaa aatcttatcc
    11641 ataaggatct tataagaaga gataagaaaa atctacttgt aacagaaaaa ggcaatagac
    11701 ttgtatcgat tgtagaggat aagtttaaat cagcagaaac aacatctgaa tgggaaatga
    11761 aacttgcaaa gattagctct ggcgaagttg ataaagaaga ctttttaaga gaaatagaag
    11821 atagtataaa ggagcttgta gataggtaca agaataatct aaatgaataa ggtaaaaata
    11881 ttagagcttt tcggcggcat aggtgctatt agaaaggctt ttattaattt aaagatacct
    11941 tatgaagttg ttgattatgt agaaatagat aaggcttgtg ttaaatcata caacgcactt
    12001 tatggagaag attataaagc aaaatcagta gtaggatata aagctcctaa tgagaagata
    12061 gacttagtta tgcatggaag tccttgccaa gacttttcaa gaataggaaa aaagcaggga
    12121 ggagcaaaga attcaggaac tagatcaagc ttactatttg aaacaattag aataattaaa
    12181 gaaatgaaag acaaacctaa atggataatt tgggaaaatg taaagggagt ccttgataga
    12241 aatatgaggg actccttttt tatttatcta aaagagctag agagcctagg atatgaaagc
    12301 aagtataaaa tcttaaatgc aatggacttt gggatacctc aaaaaaggga gaggatattt
    12361 gttgtttcat gtcttggagc aaataacttt tcttttaata aattggagag gaaagaaaca
    12421 agaccactaa gtgaattttt tgaaaaggat gtaagtgaac tttatacaat gacccaacct
    12481 tatatgctga aatttttaaa taaaggtata gataacagtt ttagagggcg actaaaagtg
    12541 attaaagatt tttcttatac tatttctaca aaacagatga gagtacctaa ttctggaata
    12601 atagatattg gaaatggtca gtataggtat ttaacagaaa gagaatgttt aagactaatg
    12661 ggttttgatg acagtgatat taacaaacta gaagaagcac atccaagaag aaaaaattgc
    12721 acttcaagta aactatataa gcaggccggc aattctattg tggtcgatat tttaatggct
    12781 attataaaag aaattcatag aatggaggta taaaatgcaa gtaaatgatt ttaagaatat
    12841 acaagaagct ataaaatatg aagtgttaca agatgaaaaa gaatatttaa aactcttaaa
    12901 ggttgtaggt aacaatcaaa aatatgattt ttctagccaa ctaagtatat ataacaaaga
    12961 acctgaagct agagcttgtg cgacttttga aatgtggaaa aaatattttg gcagagttgt
    13021 tatgagaggt caaaagggca ttccaatttt agttggaagt gatataaaca aaaaagtttc
    13081 atatattttt gatattagtc agaccacatc aatggatagg aatattaatg aggttagctt
    13141 atggcaattt gaccacgaaa accataacga ggctttaaaa gaaataataa ataattcttc
    13201 atttgaagct agtgattcac tcaatgaaaa tatattttct ttgagtcgaa tttatggaga
    13261 tgaatatatt aacttggctc ttgctgattt aaggatagat atagaggata gacttagttt
    13321 tgaaaagttt atgagggact caatatccta tgcggtagct aataggttta atacagccta
    13381 ccctatggat atggaaaatt taaaaaataa tttttctagg attaatacaa tttctttaga
    13441 gcagataggt cttgtaatat caagggttag tgaagatatt atagatagaa caatagaaaa
    13501 atctaaggaa atggatcgag ctaggctgct gacagaaagg gctggtggcg actataatag
    13561 agatatagaa aatataaatg aagatagagg aggtcaagat gatttatata gacgagatga
    13621 taggtcaaga agtagagatg gacgagtttt cacagatgga agcgacagaa gaaatagcaa
    13681 tgaagatcga agagaaaacc ttggacatga tggagaagga tctggaattt atggagagat
    13741 ttccgaatcc aacatacgca gttctaagac tgtcttacct ggtagggagc gaagacatgg
    13801 agaactggaa gaaacttcag aaaatgtacg aggagaaaac acttttgaac cacctgaagg
    13861 aaattcagaa tcaggcagtg gactttatca agagagagaa agtcaagatg atgaaagcac
    13921 aaggattgac agagaaaatg atgagaggga atccagagga ataccaagga cagatgaaca
    13981 acttgatggc aacagtgaag aagatggcaa tcaaggaata cgtggaagct tagaaaatga
    14041 aataagtcca gaaaaggaag ctgatgaagc ttcttttttt gatggcaaaa acactgaaaa
    14101 tagaaaagat tactggattg tagaatttaa tgaaaatcac gaattagttc ccgattatag
    14161 tgggcagata gtaactaaag acttaatcaa tatcctaaga caaaaggata ttgatattaa
    14221 agaccataat caaactcatg gagaaaatga atttggagaa atgactgatg attatatcgg
    14281 atatttcaaa ttctattttg accactatgt agacggcgaa gttgtcgaac actataggat
    14341 tgaccttggt gatggtgtag aagtaaatga gcgtgaattt tcatatttag aagaacaagt
    14401 tgcaataagc gaggaaaaat ctttacaaga agaagtaaag gaaaatatag agcctaaatt
    14461 taagataggg gatcaggtta gatataaaga taaggacttt accattacag attttgatgc
    14521 actaagtgga ggacttaaaa ctgtaaccat cagagataat atggaatata tgggaggtat
    14581 gattaggggt tcggaagtaa ttccatatag aaacgattca taccttgaag aaatctttga
    14641 aaatctaagt caaacatcag aaaaaatagc agtaaaagtt ggaaaagaat ttattttaga
    14701 agatgagaat gcttttcgta gaattaactt aattgaaact ggaactaaag tagaaattaa
    14761 tggggatgaa attcctttat ataaaggcga aacatttgaa gaaagtagaa aaattgatga
    14821 cctttttgat agtggagatt atgaaatata caagttatct gagcatgaaa atcaaattga
    14881 aagacaagta gagcaagaaa gttttattga taactacaat ccagaaattg accaaatgat
    14941 ggataggtat gatgtcccaa gacaagcagc cgaaaactta ttgaggggta aagaagattt
    15001 aaagaatcta ggctatgaac ctaataagga aaagttaagt tttgctagaa attacgactt
    15061 aaaaaatcat atctactcag aatacctaac accatcagaa agactagata aaaatataaa
    15121 agctattaaa atgctaaaaa gacttgaaaa tgaaaatagg agtccaaggg agtatgaaca
    15181 agcctatctt gctgactatc taggctgggg tggtcttgcc gatgtcttcg atgaagaaaa
    15241 aggaggtcaa tggcttgaag caagaaatat tttaaaagaa aatctaacaa atgaagagta
    15301 tttgaatgct aaagagtcta ctctaacatc cttttataca cctagagagg taatggatgg
    15361 aatatataag actctaacag atattggttt taagactggg aatatccttg aaccatctgc
    15421 aggagtcgga aatttcattg gtaatatgcc aaatgaaatg aaagcgtcta aaatctatgg
    15481 agtagaaaaa gatagcctaa gcggaagaat agccagagaa ctttatcctg aagctaatat
    15541 tcaaattaaa ggttttgaag aaacaaactt ctcaaacaat ttctttgatt tagtaattgg
    15601 aaatgttccc tttggagatt ttaaagttaa cgatcgtgaa tataacagaa ataattttct
    15661 gatccacgat tatttttttg caaagtcaat agataaggta agaaatggag gaattattgc
    15721 cttcataact tcatctggaa ctatggataa aaaagatgaa tctgttagaa aatatattaa
    15781 tgcaagatgt gagtttttgg gagctatgag gcttcctaat actacattta aaggacttgc
    15841 tggtacagaa gttacttcag atattatttt tctaaagaag agagattcag ttatagaaag
    15901 agatgacgat tggattcatc tagcaactga taacaaaggg ctgacctaca acaaatattt
    15961 tgtagataat cctcaaatgg ttttagggga tatgaaagaa gtatctggta gatttggaaa
    16021 taccattact tgtgatgaaa aagaagacga aaatttaaaa gatttaatgg atcttgcaag
    16081 taaggaaata tcttcaaatt caaaatatga agaggttgag ctattggaag atgaagaatt
    16141 aagtcttcca gcaacagatg atgttaagaa tttttcttac accattattg atgaagaggt
    16201 ctacctaaga gaaaactcag tcttaataaa gcaaaatata tcagataaaa acaaagaaaa
    16261 gataaaagat tatcttgatg taatgaatgc tttgaaagat gtaatagaaa agcaaaagga
    16321 tgatttttca gacgaggaaa taaaagagtc acaagcaaag ttaaacgaag tctatgataa
    16381 ttttacaaag aaacatggct ttattaactc cttatcaaac actagagcct taaaggaaga
    16441 ctcaaacttt cctttagttt catcaataga aatacttgat gatgaggata atttcaaagc
    16501 taagagtgat atattctcaa aaagaacaat aacaaaggca aaagtagtag accatgtaga
    16561 tacttccctt gaagctttag tcttatctgt ttcacaaaag ggatatgtag attttgaata
    16621 tatggaatct atcacaagta aagataggga gaccttaatt ggtgaacttg agggcgagat
    16681 atttttagat attaaggata cagacctaat aaataacaga atgccctttg aaaactttaa
    16741 taatgacgat ccatttcatt tttcatatgt atcggctgat gaatatttaa gtggaaacat
    16801 tagagaaaag attggttacc tcaattcata catcggagaa attgaaaatg taatagattt
    16861 agcaccttat gaaaagaaag acacattatt aaacgagtta ggcaaactta aatatcaaag
    16921 agaaaaatta caagaagtta tgcctgaaga actcactgct tctgatataa atgtaagatt
    16981 aggagcaacc tggatacctc agaaagatat agaagacttt acttttaatc ttttaaaaac
    17041 accaggttat gataggtgga atataaatgt taggttctca ccacatacaa gtgaatggaa
    17101 cattgaaggt aaaagtattg actcaactaa tgaccttgct aacatgactt atggtacaag
    17161 tagagtaaat gcatataagc taattgaaaa tgctcttaat ctaaaagata caaaggtatt
    17221 tgaccaagta ataaatgatg atggttctaa gacttctgta ttaaacaaaa aagaaactat
    17281 gcttgcaagt caaaagcagg aactgattaa agaagaattt aagaattgga tatttgaaga
    17341 tcctgataga agatataggc tagagaagat ttataatgaa aaattcaatt caattagaaa
    17401 tagagaattt gatggttcta acttaacttt tgatggaatg aatactgaaa ttagacttcg
    17461 agaacatcaa aaaaatgcaa tagctaggac tctttatggt ggaaatacac tacttgccca
    17521 tgtagtagga gcaggaaaaa cttttgaaat ggtagcttct gctatggaat ctaaaaagtt
    17581 aggacttgca agtaaatcat tatttgtagt tcctaaccat ctaactactc aaattggtag
    17641 ggagtttatg caattatatc cgtcagcaaa tattatggtg gccgataaaa aagacttcca
    17701 acctaaaaat agaaaaagat ttattggcag gattgcaacg ggagaatatg atgcagttat
    17761 tataggacac tctcaatttg aaaaaatacc aatgtctaag gaataccagg taaggcatat
    17821 acaagatcaa atagatgata tagtttcctt tattgatgag aacaaaagaa atagaggaga
    17881 aaatttcaca gtaaaacaac tggaaaagac aaagaagaaa ctcttggtaa gacttgaaaa
    17941 actaaatgat gactttaaaa aagatgatgt aataaccttt gaagaactag gagtagataa
    18001 gttatttata gacgaagctc ataattacaa aaacttgttt ttgcatacaa agatgagaaa
    18061 tgttgcgggt atcggtcaga gtgaagcctt taagtcttcg gatatgtata tgaaatgtag
    18121 gtatatggac gaaatgacag atggaaaggg agttgtattt gctactggta caccaatatc
    18181 aaattcaatg acagagcttt ataccatgca aagatacctt caatatgacg atttaaaggc
    18241 aagaggatta gaacattttg acgcttgggc ttctaccttt ggagaaacag aaaacacctt
    18301 tgaattatct ccagagggct atactttaat aggacaaaaa aattaactgt cctaaattga
    18361 aaaaatacat acggaaagga ggataagaaa atgtcaagga cttcaagaat tacagcactt
    18421 tacgagcgtt tgtcaagaga tgatgacctt actggcgaga gtaattctat taccaatcaa
    18481 aagaaatacc tcgaagatta tgcccgtagg aatggttttg agaacattcg ccattttacc
    18541 gatgacggat tttcgggtgt aaatttcaat cgccctggct ttcaatctct gataaaagaa
    18601 gttgaagcag gaaatgtaga aaccttgatt gttaaggata tgagccgatt ggggcgaaat
    18661 tatctgcaag taggttttta tacggaagtt ctgtttccac agaaaaatgt ccgtttcctt
    18721 gcaattaaca acagtattga cagtaacaac gcttcggata atgactttgc tccgtttttg
    18781 aatattatga acgaatggta tgccaaagac acaagcaaca aaatcaaggc tatattcgat
    18841 gcccgtatga aagacggaaa gcgttgtagc ggttctatcc cttatgggta taaccgactg
    18901 ccgagcgaca aacaaacgct tgtggttgac cctgtggctt cggaagtggt aaagcgtatc
    18961 tttactcttg ccaatgatgg caaaagtaca agggcaatcg cagaaatact gaccgaagaa
    19021 aaagttttaa cccctgcggc atacgcaaag gaataccacc ccgaacagta caacggcaac
    19081 aagttcacaa acccttatct ttgggcaatg tcaacgataa gaaatatttt aggcaggcag
    19141 gaatatctcg gtcacaccgt tttgcgaaag tcggtaagca caaatttcaa acttcacaag
    19201 agaaaaagca cagacgaaga agaacagtat gtatttccga atacacacga gcctatcata
    19261 tcgcaggaac tttgggacag cgttcaaaaa cgcagaagca gagtaaatcg tgcctcggct
    19321 tggggaacgc acagcaaccg tttaagcgga tatttgtact gtgccgattg cggaagaaga
    19381 atgactttgc agacacatta cagcaaaaaa gacggttctg tgcagtattc ttaccgttgc
    19441 ggtgggtatg caagcagagt gaacagttgt accagtcatt cgattagtac cgataatgtt
    19501 gaagccttga tattatcatc tgtcaaacgc ttttcaaggt ttgttctgaa tgatgaacaa
    19561 gcatttgctt tggaactgca atctctttgg aatgaaaaac aggaggaaaa gccgaaacac
    19621 aatcaatcgg aactgcaacg ctgtcagaaa cgctatgacg aactctctac ccttgttcgt
    19681 ggcttgtatg aaaatcttat gtcgggatta ctgcccgaaa gacagtataa gcaactgatg
    19741 aaacagtatg atgacgagca ggcagagttg gaaacgaaaa tggaaacgat gaaaacagaa
    19801 cttgccgaag aaaaagtaag ttccgttgat attaagcatt tcatttcgct gatacgcaag
    19861 tgtaaaaatc ctacggaaat ctccgataca atgtttaatg aacttgttga taagatagtg
    19921 gtttatgaag cagagggtgt gggaaaagca cgaacacaaa aggtcgatat ttattttaac
    19981 tatgtcggtc aagtggatat tgcctatacc gaagaagaac ttgccgagat agaaacacag
    20041 aaagagcagg aggaacagca acgcttggca agacagcgca agcgtgaaaa agcctaccga
    20101 gaaaagcgaa aggcacagaa aatcgctgaa aacggtggcg aaatcgttaa gacaaaggtt
    20161 tgccctcatt gcaacaaaga gtttatcccg acaagcaacc gacaggtgtt ctgttccaaa
    20221 gagtgctgct atcaagcaag gcaagacaaa aagaaaacag accgagaagc agaacgagga
    20281 aatcactatt accgacagcg tgtatgtgct gtgtgcggca attcctattg gcctacacac
    20341 agccaacaga aattctgctc cgaagaatgt caaagggtaa atcacaataa gaaaacattg
    20401 gaattttacc accataaaaa agaaaaggag aagctgcaat gcaaagattt atcacagacg
    20461 aaagaacggg tatccgatat gaacttatcg gggactatta ctacccctgc ttaaccgcag
    20521 aagaaaaacc tttgctttca aggtacggaa gaatgcgaga gcgatatttg aaagaacaca
    20581 agcgagtttt atattacact ctgatgacaa gtggaaagtt atatgaacac cttgccgaga
    20641 ttgacacttc ggcttgtgat atggctgaat atctcataaa ggaaatggca agaaagcaag
    20701 gcgttaccga gcaattaaag gctgtggata tgatgagatg gataggattg atgaacaata
    20761 tcagagcttg cgtagatgaa atcgtattaa acgatattgt gtattcataa cggaatacta
    20821 tccgaaagag aactgctgtc aagtgatggc agtttttctt tttcggcaag tgttcaagaa
    20881 gttattaagt cgggagtgca gtcgaagtgg gcaagttgaa aaattcacaa aaatgtggta
    20941 taatatcttt gttcattaga gcgataaact tgaatttgag agggaactta gatggtattt
    21001 gaaaaaattg ataaaaatag ttggaacaga aaagagtatt ttgaccacta ctttgcaagt
    21061 gtaccttgta catacagcat gaccgttaaa gtggatatca cacaaataaa ggaaaaggga
    21121 atgaaactat atcctgcaat gctttattat attgcaatga ttgtaaaccg ccattcagag
    21181 tttaggacgg caatcaatca agatggtgaa ttggggatat atgatgagat gataccaagc
    21241 tatacaatat ttcacaatga tactgaaaca ttttccagcc tttggactga gtgtaagtct
    21301 gactttaaat catttttagc agattatgaa agtgatacgc aacggtatgg aaacaatcat
    21361 agaatggaag gaaagccaaa tgctccggaa aacattttta atgtatctat gataccgtgg
    21421 tcaaccttcg atggctttaa tctgaatttg cagaaaggat atgattattt gattcctatt
    21481 tttactatgg ggaaatatta taaagaagat aacaaaatta tacttccttt ggcaattcaa
    21541 gttcatcacg cagtatgtga cggatttcac atttgccgtt ttgtaaacga attgcaggaa
    21601 ttgataaata gttaacttca ggtttgtctg taactaaaaa caagtattta agcaaaaaca
    21661 tcgtagaaat acggtgtttt ttgttaccct aaaatctaca attttataca taaccacagg
    21721 ttagtacaaa gaccttgtgt ttctttttga aaggcttaaa acaaggattt ttccttgatt
    21781 taagccccga aaagcaacac aaccaaggtt ttagtatcaa tctgtggttt ttatattttc
    21841 agagaaaagg agaacaagaa aaaatgaaac taaatgaaaa cgaaatgaat ttcagcgtac
    21901 ctcttgaaat catcaaggca agtgaaatcg agccgaaaga agtaaagtgg ctgtggtatc
    21961 cgtatattcc gtttggcaaa gttacgctat tgcagggaga tccgggcgat gggaaaagca
    22021 agttaatgct ttccatcgcc gccctgctct caaagggcga acctatcccc tttaccgaaa
    22081 cggaagaaaa tgagcctatg actatcatct atcagacaac ggaagatgac gcagacgata
    22141 ccgtagtacc ccgcttcaat tctgccggcg gagacggaga aaatcttatc ttcatcaagg
    22201 aagatgaaaa gactttatct ttcggagata accgcattcg tgaagcgatt gaaaagtaca
    22261 atgcaaagct tctaattctt gacccgttga gttcgtatat cggagagaat tgctctatga
    22321 ataatgccaa cgaaacacga gcggagttta accatctgat agcggttgca aaagatacgg
    22381 gttgtgcgat tgtcattatc gctcatatga acaagatgaa agataataat ccactctacc
    22441 gcaccaacgg ctcgattgac attgcgggtg ctgcaagaag cattcttgca atcacacgca
    22501 caccgaacaa ggaagcacct gcggaaagat atttggtgca agtgaaatca aatcttgctc
    22561 cgacaggttc ggcaattctt tttgaggttg ccgagaaagg tgtgaacttc atttccgaaa
    22621 tggaaatgac agccgaagaa gcgtttttat ctcttgcccc acaaataggc agaccgaatg
    22681 aaaaagagat gaaagcaaaa tcatttctca ttgaaatgtt gcagggcgga gaaatgcttt
    22741 cttcggattg tgaagaaaaa cttgaagccg cagggttcaa gaaatcgacc atcaaaaagg
    22801 caaagaaaaa cgcaggagtt atctccaaga agaaaggttt tctttggtat tggtctttgc
    22861 cgatgagcga tataccgaga gaataaaaac agaatgcctg tcggtgggac agtctgtttt
    22921 tgtgattgag gtatcaaagg aggtcaaggg ggaacaccct tgcccacgac atctttgcag
    22981 acgaagtctg aaagtgtcat agtgggttac acacattcaa agaatgttgt gtaatggctt
    23041 cgccctgccg agaaaggaga gcaaaaatgg cgaaaaacaa caaggcggat atgagttgtg
    23101 caagggttaa aaagtacacc gcttctgatg tgagcaaggc agaaaggcac aacgaacgca
    23161 agaatgaaac ctatgaaaat atgaatgtga ttgaggaacg cataccctat aatgtgcatt
    23221 tcaaaaagcc ttttgccccg acctatatgg aacaattaaa gcagatggaa actgacggta
    23281 tggtgtcgct tcgagggctg aggaaagacg caacgctgtt caatgagatt gtgattgatg
    23341 tgaacacaat gtacttcgag cgtaacggcg gctacgaata tgcaaagcag ttttacgaag
    23401 aagcattcca ttttatcgag gaaaaattcg gtgctgataa tgtcatatcg gctgttatgc
    23461 acgctgatga aatcaatgta gcggcaaccg aggaacttgg aaaagaggtt taccactatc
    23521 atcttcacgc tatggttttg cctgtggtgg agaaagaaat cctatggagc aagcgttgca
    23581 aagatgaaaa actgcgagga acggttaagg aagttgttca tcaaatcagc cattcaaaga
    23641 aatggaaatc ggatattccg ctgaccgacg aaaaaggcaa tccgcttctc agaaagaacg
    23701 gaaaaccgat gttccgagct tcatacagta ttctgcaaga tgaattgttt aaccatatga
    23761 cggagcaagg cttcaaaggc tttcagcgtg gcgaatatgg aagtacagcg gaacatctta
    23821 cttccctaca atatcaaatc aagcaggaca aggaacgatt agagaagttg cagaagcgta
    23881 ttcagcgtga acagataaag tatgagcctg cccgtaatgt ttccaaaacc tataacgaga
    23941 ttgaccgtat ggggcagaaa acaatcacgg gtaaaatggc aatctccaaa gaggattatt
    24001 ctgagcttac tgcccttgct aaagagggca ttaccagtcg tgcggaaatc agcgaattag
    24061 aacagagtgc aaactattac cgacagaaat attttgacag tgcaaacgca cttgaaagaa
    24121 tgaaaaccaa atacgacgaa ctgaaagaaa agtgcagacc ttttcttcaa gcgttggagc
    24181 atttccccga agttgctaaa ctttttaccg agaaagtgaa gcaacttttt tcttttaagg
    24241 aagcgcagga acgagccgaa aaagaagcaa gggaaaaaga acgacaggag cgtatcaagg
    24301 ctcgaagaaa caagcgtggt atggaaagat aaccttttcc attatactca cgacttaatg
    24361 acttgttgat atattgaaaa tctgcggttg atgggtgttc taatgtgaat acccatcaat
    24421 caaaatttta tgaaagagag gaacggacta tatgaaagaa cagaaacatt cttattcaca
    24481 atgcattgga aagacaacat tcatcgtaaa tgtaaagcag tctgaaagtg ccaaaaagcc
    24541 tttgaatacg gtgtttcaag acatctgcaa gcacgaggtt ttgggcgatt tctttacgga
    24601 caaatcgttt aatttagaaa atccacaaaa agtatcttga caaactcgac cccgaaggaa
    24661 ctgggtatag acaaaagaca agattttcaa agttctataa cttgccagaa ctgatgagca
    24721 tgtttaaaga agtagcagat ataaagactt cagatatgtt aaatttgcca gtgccagaag
    24781 caaattttga agttattaaa acaaaaccta ctgaggaaca aaaagaaata ttagaagcta
    24841 tttcagaaag agcagacgca gttagaaaca accaagtcga accaacagaa gataacatgc
    24901 taaagattac aaatgatggt aaaaaacttg cccttgacca aagattaata aatccattac
    24961 ttccagatga tcctaattca aaggtaaatg tatgtgttaa aaatatcttt tcaatctggg
    25021 ataagacaaa agaagattca tcgactcaat tagtattttc ggatatgtcc acaccaaaag
    25081 gagatggaga atttaatatt tatgatgata ttagaaataa gctagtgaat atgggaatac
    25141 ctaaagaaga aatagccttt atccacgaag cagatacaga caaacaaaaa gatgaactat
    25201 tctccaaggt aagaagagga gaagtaagag tattattagg ctctacacaa aaaatgggag
    25261 caggtacaaa tgtacaaaat aaactaatag ccttacatga tttagatgtc ccttggagac
    25321 catctgacct agagcaaaga agtggtagaa ttgttcgtca aggtaatgaa aatgataagg
    25381 taaatatatt tagatatgta actgagaata ccttcgatgc gtatttgtgg gtgcgacatg
    25441 aagtcgctta atttaactgt ttggcatgat gaccaaacca actattccgt tagttgagcc
    25501 gagtatcgac tgcacttaag tgtggtaagc cgatattaaa gtagccctac ttgaggtaaa
    25561 accgtgagga aataccgaaa ctgccagcaa caaagtggtt agggagcgag gcttgataat
    25621 atggctaaca tatgtgaact actgataaat gtcgttaagg cgaacaggct aaagttgctg
    25681 ataagcctga accaaaatgg tgtgtagtcg gataatcctt tccacagtgg gattacacgg
    25741 acaaaaagac taccggcaga gaggtagagc ctaagttatc aatgttaatt aagtgaaaca
    25801 tggtaagcct gtactattgc caaaaggcaa ggcaaatcgt aagaaatgct gataatggtg
    25861 caggtaaagg agaatggaaa aagcgaatgc catcttgtaa tgagatggat aggggttcaa
    25921 aatttgccct aacttgaaag agtgcagact tccatttggt ttttaatcac aagagaactt
    25981 gtagaatttt tgaaaggaga aagcaaatga acagtaaaat gtgtgctact actaacagag
    26041 ctaaaaactg ggaaagtata gacttttctc tagcagaaag ctatgttaaa aaactacaaa
    26101 tgcgtattgt gaaagcgtgg aaaatgagta aatatggaaa ggtaaaatct ttacagcatt
    26161 tactcacaac ttcattttat gcaaaagcct tggctattaa gagggtaact gaaaaccaag
    26221 gcaagaaaac aagtggtgta gatggcgaat tatggctaac accacaggca aagtataagg
    26281 cgatagaaaa gttaaattta agaggatata aacctaaacc tcttaaaaga gtgtatatac
    26341 caaagaaaaa tggtaagaaa agacccctca gcattcccac aatgacagat agggcaatgc
    26401 aaacactata taaatttgca cttgaaccca tagcagaaac tactgctgac cctaattctt
    26461 atggatttag ggcaaaaaga tgtacacaag acgctatcga gcagtgcttt acatcactta
    26521 ataaaaagaa atctgcaaaa tgggtacttg agggagatat aaaaggttgc tttgataata
    26581 ttagccacga atggataatg aataatattc caatgaacaa gtcgttattg aaactttggc
    26641 ttgaatgcgg atatatagaa aagcaaagat tatttcctac agaaactgga agcccacaag
    26701 gttcaccaat atcacctgta atatctaata tggtattgga tgggttagaa aaagcaatca
    26761 aagaaaaata tcataaaaga acagtaaata agaaagcata tttcccaaaa gttaattttg
    26821 taagatatgc agatgatttt atcgttacag gagaaagtgc ggaattgctt gaaaatggtg
    26881 ttaagccaat cattgtaaaa tttttagaag aaagagggtt agaactgtct gaggaaaaga
    26941 cactcataac gcacataaat gacggtttcg actttcttgg agttaatatt aggatgtata
    27001 aagataagtt actaacaaaa ccatccgaaa agaacttcaa ggctattgtt gataaaataa
    27061 ggcaaatcat aaaggataat ccgtcaatga aacaagaaat tctgattaga aaattaaatc
    27121 caattattat aggttggata aactatcaga aatataatgt ttcatcaaaa gcgtttgaaa
    27181 aacttgatta tgaaatatat aaatgcctgt ggaactggtg tgttcgtaga catcctaaga
    27241 aaagtagaaa atggatagct aaaaagtatt tccatacgat tggaaataga acttggactt
    27301 ttagtgtagc aactggagac agaatggaaa atggcgagaa atactatctt cgtcttaaat
    27361 atgctacaga tactgatatt aagagattta ccaagataca agctgaagca aatccatttg
    27421 atgaaaattg gcaaatatac tttgaagaaa gagaagagtt aaaaatacga aacgaactta
    27481 aagggcgtac agttataaat agactgtata aaacgcaaaa cggaatatgc cctgtttgtg
    27541 gagagaaaat aactctggat acagacttta gagtacatca aacaactcaa aacaatatta
    27601 cccttaaaac attagtacac ccttggtgtc atagaaaatt gcatataaat gataaagaaa
    27661 atacgctggc tctttaatta gggcttataa aaacttgagc cgtgtgaggg gaaactctca
    27721 tgcacggttc ttagagggga aagggatagt aatatccccg acctactcga ccagacgata
    27781 gagaataagc aaaaattcat ttctcaaatt atgacttcaa aaactccagt aagagttgca
    27841 gaagatgttg atgaagcaag tctatcttat tcagaaatta aggctttagc tacgggtaat
    27901 cctctaatta aagaaaaaat ggatttagat aacgaagtta caaagctaaa aatgcttgaa
    27961 gcaaactaca agtctaataa atataagctt gaagacaagg taaataaaat ttatcctcaa
    28021 agtattttaa aaactgaaat ggaaatacaa gcagttaaag aagatattgc aagtgttgag
    28081 aaattaggag aaggagatag caaattcact tcaatcagcc ttggtgcaaa taaaatttta
    28141 gataagaaag aagctggaga gaagctatta gaagaaataa aaaaggtaaa gataaatgat
    28201 agcaaggtta ttggtaaata taggaattta gacttacaag tttcatataa ctttatgact
    28261 aataatcaca cctttaaact tctaggaaaa gcagaatact tcggagagtt ttcaaactct
    28321 actgatggta atataacaag gcttgataat gccattgaaa aaatgccttc aagacttgaa
    28381 agattaaatc aaaatcttga aaactatgaa gaatctttag aaaatgctaa agtagaatta
    28441 actaaaccat ttgaaaaagc agatgagtta agggataaga cactaagatt agctgaaatt
    28501 aataaacttt tagatatggg agaagtggaa gaattagaaa accaatcacc actattagaa
    28561 gatttaaaaa gggcgatagt tgattatact aactacgagt tttcagaatc taatagttat
    28621 gaagactttg acaaactata ccctgattta agccatatag gacttgccta tacagaaaca
    28681 ccagatggta agcactctat tcaatatgag gtaaatttgg aagaaaaaac atggagtcag
    28741 tatgtagatg atgtagctat tagaacagaa tcttttgtag aagaagatat gtctaactca
    28801 caagctatta aagatatgac tgaagccata aagatgtcaa gttttgatga tctggtatca
    28861 gtagatgaag aagatttaaa acaagcctta ggcttagaaa tagatgatga tggaaacttc
    28921 tatgatccac tagcaaaaga tcttgataat gatggaatac cagataggta tgacaatgat
    28981 tttaaagaca gtgattactt tgaatcaact tatgatgtag aggataatct tcacgcaagg
    29041 gaagagaaac catcaatatt gggacaaata tcaaaattta aatcagaagg agaaaaagat
    29101 aaaaatcaag aaaaaaacga aaaaggacaa gaaaggtaga ggggagcgaa aggctctcct
    29161 tatttagtac aaggaggaaa ttatggaata caaagatatt agagaaaatt tagaagaaat
    29221 gatgaatgat aattacaagg attttataaa agcaattgtg agcatagaaa aaggcattaa
    29281 tgatgaaaag gcacttgaag aagtctatgt tttatatatg aacaatgaca caacaggttt
    29341 actaagtgat gactttgact atatgattga tgatatgaaa gaacaaggaa agatagttga
    29401 aaatgtcagt gatattgaag aaaaagacga tcttataaat ctcgtgggta atatagctgg
    29461 aaaagtagaa aatcttgaaa gagaaaatgc taatggagaa aaattcaagg taagcaattt
    29521 ttcaattgtt tcaaaagatg acgatgggaa taaaatttat accaattgtt cagcatatgg
    29581 agataagaca aaagatatag agaatctaaa acaaggagat tttgtaaaga tatttggtca
    29641 agtaaaaaca agcattgata acaacggaaa ggaacataaa aatgttcgta ttttatcttc
    29701 taagctttta aaagcaaaag aacaagtaaa gagtcaagat aaagataaaa agtccatatt
    29761 agggcaaata aaaagcttta agacagatga caaagctaag tcaaataaga aagaccacag
    29821 caaaggtaca gagagataaa tatcggcagt ctacggactg cctttatttt ttatatgtat
    29881 ataggttgta taatgacgta ataggggaaa ggtgttttaa atatatttca tatatttttt
    29941 gaccactcta ctgtatcttc catccgataa cttttctccc tagacatatc cataatatgg
    30001 gccctatgag caagtctatc aacgatagcc ccagtaagca tagaatcttt aaaaacctac
    30061 tcccatcttt caaagttcaa attcattgtt aaaattattg attccttatc aattctagat
    30121 gataagagtt taaggaatct cacatcctat cttatcaaat gaaacataat caggctttga
    30181 ggtgaattta cgtaaagagc aatgctaaag cttaaaaaat acctatctaa caaaggtgaa
    30241 tttttatttt tatcatatta tgtagatgga tgtaaatgaa tattattttt aagtatatgt
    30301 tatttttaat tgcttcattt catattgact ggatcggtca attttgatat actctaaatg
    30361 actagttggg tcatcggttt ataaagaaag gtggttttga tcatttattc aaaatttaat
    30421 aacttaaaac cagaaaaaca aaagcaaatt attaacgcag ctataaaaga atttgttcga
    30481 aatggttttg aaaaagcatc tactaacgaa attgtaaaaa gagctaatat ttcaaaaggc
    30541 tcgctgttta actattttaa cagtaaaaag gatctttact tgtacttgat tgagtatagt
    30601 agtaaagcaa tcgtgaatct aaatgaagaa attgatttgt ctgaaactga tttatttaaa
    30661 agaatcgaaa gagttgcttt acaaaagttc tatgttcaac aaaagtaccc acaggcattt
    30721 gaattcttgg catcaactaa acaagaggag tctgtagaag taaaggatat cattaaacaa
    30781 aggctcaatc caatctataa tcaagccata aataaattat ataaagacat tgattactct
    30841 aaattcaggg aaggagttga tattgaaaaa gcaattgaga ttttgaattg gacgatgttt
    30901 ggtgtaggag agaaaggact aaaggaattg tttacctttg atgatattgg tagatttgga
    30961 gagaaatatc tagaagagtg gaacgtttat gccgaattac tgaaatacag cttttataaa
    31021 taaaactaaa ttaaaggtgt attgaaatga aaatataata gctttagatt tttatctaaa
    31081 aaaattttaa aggagtgtgt ctatattatg accgatatag taaaagtaca aggattacaa
    31141 aaaaagtttg gtaaatttca agcattgcgt gacgtttcgt tcacgataaa atcgggggaa
    31201 gtggttgggt ttattggtcc taatggtgct gggaaatcta caactattcg tgccctatta
    31261 ggaattataa aacgtgatgc tggtattgcc gagatattcg gtaaggatgt ttggaaggat
    31321 agccttgaaa ttcataagcg aatttcttat gtccctggag atgttgccct ttggggatct
    31381 ttaacgggag gagaaattat cgatctcttc attaaattac atggtagtgg agataaagaa
    31441 aagcgcgatt atttaattaa acgttttgaa ttagacccta agaaaaaagc caaaggatat
    31501 tcaaaaggaa atcgtcaaaa agttggattg attgcagcat tatctgttga ttctgattta
    31561 tatatttttg atgaaccaac atctggtctt gatcctctaa tggaacaagt tttccaagaa
    31621 gaagttgaaa aaattaaagc atctggtaaa gctattttat tgtcctccca tattttaagt
    31681 gaggtagaac gattagcaga taaggttgta attatacgcc aaggtgaaat tgttgaaact
    31741 ggaacccttg atgaattacg acatttaact aggtcaactg tcactttagt gacaagtgga
    31801 gatgtatcaa aaatggcttt tgtagatgga gtacatgatt ttgttcaaaa tgatagccaa
    31861 gcaacattct ctgtcgataa tcaatatctc aatagtattt taattgaagc tagcaaatta
    31921 ggtgtcacaa ggtttgaatc tataccgcca acacttgaag atttgtttat gcgtcattat
    31981 gaaagctaaa ccgtgggaag gtggaaaaat tattatgaaa gaaaaatttg ctcgttggaa
    32041 catattgttt ttacagtatt taaaacgaga ttggaaaaaa attattatat gggtattggg
    32101 acttggcatg ttttcggctg gatttgttcc agctttcaaa gaaatagcaa aagggcaagg
    32161 tttagtcggc atgttcgaaa ctttgcaaaa ccctgcaatg atatctatgg tagggccgac
    32221 cccagttgaa acaggagctg attatacctt aggagcaatg tatgcacatg aaatgttgtt
    32281 gttttgtggt ttgtttgcga tgataatgtc tattttacac gtgataggtc atactcgtaa
    32341 agaagaagat cttggcctta ctgagctact gcgttccttt caaataggtc gtcaggcaaa
    32401 ttctcttgca gcaatagcag agatagtctt tatcaatggt atactagcac tttttattgc
    32461 agtagtaatg ataagtttcg gtgccgatac gatttctatt tttggttccg tgttatacgg
    32521 ggcatcaatt ggaatggcag ggattattgg tgctgggatt gctctaataa tggcacaaat
    32581 tatgcccacg tcatcggctg caacaggatc atcattagga attgtaggct tactatacat
    32641 tgttcgtgct ggaacagatg tctccaatgt tgacttatct atgatgaatc ctttgggctg
    32701 gacatattta acttttcctt ttacagataa taattggttt ccacttattt ttgctttaat
    32761 tttcagtata atagtggtgt tcatagcttt ttcacttgaa ggtggccgcg atatgggggc
    32821 tggatattta ccgcaaagag aagggcgtga aagtgcaaag cagtctttgc tgtccgtccg
    32881 aggattattt ataaatatta ataaaggtgt cattattagt tggttaatcg catatgttgt
    32941 tatgggtgct gcctatggtt cgatttatgg agatatgcag acattcctag aaagtaatga
    33001 aatgatgaaa caaatgtttt ctcatacagg attttctatt gaagaatcat tcacaggcac
    33061 agttatgatg gttttgattg gtttagtttc cattctacca attgcgattg taaataaact
    33121 cttttctgaa gaaagacgat tacacttaag tcagatttat gcaacaaaag taacccgcag
    33181 tcaattatat tggactagta tagggttatc gatattaagc ggattattag gagttttatt
    33241 agcagcaggt agtcttggag gtactgctat ctctgcgatg gggaatagcg gagagatgga
    33301 tatagttgac ttttttgctg ctggctttaa ccttttccct actgttttat tctttatagg
    33361 tctggcagcg ttagctcttg gatgggcacc gaaactaggt aaaatagtgt atatttatct
    33421 tacattctct tttttattaa attattttag cggcttaata gacctcccgg aatggttttt
    33481 aaatactgct atacaaagtt ggatgcctca aatgccaatg gatgattttg aagcatcagt
    33541 ttttcttaca gttactataa ttagcattgc tttaatagta ataggttttt tggggtatag
    33601 tagaagggat atgaatgaag gagcttaaat tgattgaata gtaaatagtg taatctaatg
    33661 atttaaattc ttgtgttgta ggttttaaca ttagtcgatg aaagcaatta aattttatta
    33721 ttacagtttc atatatttga taaggataga agtattctaa actagaatta tatttcgatt
    33781 cttttggcga ccattagaaa gctagtcgtt atgttctcac gaacgtacaa attagtcgat
    33841 atgttcccat atacaacatt ttcgctaaaa atcataaata catcaattct atcaactcgt
    33901 cccacgttga agcagcaatt ctgatgacgt attgtggttt ggacaaggaa taataggagt
    33961 caaccacaac atgtagtggt ttgagtacga aaattgggtc aaaaataggc taaaaaatac
    34021 cgttttttga cccttttaaa tagggcattt gacagatgac atttgatgtt tcgggattaa
    34081 aaatccatag ggtgaggtag attagcacag aactttattg aatagagaaa ttaaaagtga
    34141 tataatcagt tgcataagga ggagttaaat atgtgtacat gtattgcagt agtagatatt
    34201 actttatctc atttataatg aaaaaaatta aaggaggtaa aggtatgggt atgttttcta
    34261 tatttgttat tgagagattt aattatcaat caaaccaaaa ataattggtt ataatgagct
    34321 cttaagatta gttcattata accggcaagg agaaggttat aatgaaacag aaaaacccga
    34381 aaaatacgca aaatttcatt acatctaaaa agcatgtaaa ggaaatatta aaatatacga
    34441 atatcaataa acaagataaa ataatagaaa ttgggtcagg aaaaggacat tttaccaagg
    34501 aacttgtgga aatgagtcaa cgggtgaatg ctatagagat tgatgaaggt ttatgtcatg
    34561 ccacgaaaaa agcagttgaa ccttttcaga atataaaagt tattcatgag gatattttga
    34621 agtttagctt tcctaaaaat acagactata aaatatttgg taatattccc tacaatatta
    34681 gtactgatat tgtaaaaaag attgcttttg atagtcaagc gaaatatagc taccttattg
    34741 tagagagggg atttgctaaa aggttgcaaa atacccaacg agctttaggt ttgctgttaa
    34801 tggtggaaat ggatataaaa attcttaaaa aagtgccacg agcatatttt caccctaagc
    34861 ctaatgtaga ttctgtattg attgtacttg aaaggcataa accatttatt ttaaagaagg
    34921 actacaaaaa gtatagattt ttcgtttata aatgggtaaa cagggaatat catgttcttt
    34981 ttactaaaaa tcaattaaga caggtgctga agcatgcgaa tgttactgat cttgataaat
    35041 tatccaatga acaatttttg tctgttttca atagttacaa attatttcaa taaattaaaa
    35101 ataattaagc gttctctaac tttaagagaa cgcttaatct tattacattg aaaaatgcat
    35161 tctattattt tcaattatta tgatataaca taactatcat tttacttatt tgcatatttg
    35221 cacgaaaata tagttatcga cgactattct gataatagca actaatatag tcaatgataa
    35281 ctcaaaattt attgatatag taggtatatg tgcaactaat tagggaagat tttagcttgc
    35341 catttctgaa acagctaaaa caagtattgc gtaaagaatg cgccagtctt cccatggact
    35401 taaaatgctt gcttggggca cacataaaac cccttgaaca atctattgac agagttgaag
    35461 gactgtcgga gattctaaga cgaagtaatc ctaaaatggc cctatgccat acagatattc
    35521 ataattggaa cttgatgcaa cgggatgagc agttagttct aattgactgg gaaggcttga
    35581 aattggctcc agtaaaagct gatctcatgt tttttgttga taagccatat tatgatgtat
    35641 ttatgaacat atacctgaaa ttacacaaag attttttaat caatacggat gctttgttat
    35701 tctatcatat tagacgtaaa ctagaagata tatgggagtt tattgaacaa cttttatatg
    35761 acaatcaaga ggataaggaa agaaatgaaa ctataaaagt tcttgatggt gaactgaata
    35821 acttagtgtt ttgaaaaaag aataacgtat tattaagcta aataatattg gagaagaaaa
    35881 tgaataaaca agaattatat caaattgctt tcagtataat taatcataaa aagttacgga
    35941 actttggaac ttcagggcat gttgcgtgcg cgttggagac aaatagcggt aacatcttta
    36001 caggaatatg cattgacttg ccctgttcta ttggcttatg cgctgaacag tcagctattg
    36061 ctgaaatggt aaagaacaat gaaactgcaa tcaaaaggat tatcgctgta tttgaagatg
    36121 ggagtatact tccaccatgt ggaaggtgca gagagtttat tgcacagata gataatcaaa
    36181 atatagagac ccaaattgta ttacctgaaa tggaagaagt gttgctgaaa gatttattac
    36241 cagaaaggtg ggatggcaaa tggaactgaa aaagataact agcagggttt tttattatcc
    36301 acatcaacca gaaactgata ggcctatgtt ggcatactta aatggagata aaattgcact
    36361 tgccattgat gcaggaaatt cagcagacca tgttgatgaa ttttataaat ccctagaaat
    36421 cgagaaccta aagaagccag attttactgt catcactcat tggcactggg accatacctt
    36481 tggaatgcat aaaattcacg gattgtccat tgcacaccat aaaaccaacg agtttttgaa
    36541 acaggaaaga gccaaactat ctgacagtgc atatataaaa tttttgataa atgatgatga
    36601 gtgcctagct agagaatatg tagataataa aagaattatt gccgttctat cggatatcca
    36661 atttgaaaaa gagcttaccc ttaatctcgg tggaataacc gcaatgattt ttcatacggt
    36721 ttcaccccat tcggaagata cggtgcttat ctatattcct gaggaaaaaa tattgttctt
    36781 gggagattca acaagcgagg atttctacaa tgatgggtat atggataaag aaaaattaat
    36841 gtcattaaca aatttgatag aaagtttcga ctgtaagtat tgtattttaa gtcatgcaga
    36901 gcctctaact aaatcagatt tattagatta cttaaaatcc attctaaaat aataatccat
    36961 gaggtgtatt gatatgttcc cgtctaccga tagccccaaa aacgcagtgg atatgttccc
    37021 gagaacggac acactcaaat gacattcatt ctatcctctc aagccatgtg gagacggtgg
    37081 tattgatgtc aaggaaaata agataatagg ctataaaagt gttgaaatta atggtttttg
    37141 gggttttaga agaaatccta aaagccattt ttctatttag ataaatatct taattataat
    37201 taaagaataa attgaggatc aagaacctca atattatata gaaaatagcc acgaagcgat
    37261 cataccaaaa gaaatcttca tgcaagtcta agaagaaatg gatagacgag ctaatatggt
    37321 aagtggcaaa gggaaaagaa gaatctattc cagtaaatac tccctttcaa gtattgtcta
    37381 ctgctctata tgtggggata tttacaggag aatagcatgg aataatagag gaaagaaaaa
    37441 aacaagttat ttatagtgtt aaattaccaa cactcttatt acttcctatg taatgtttac
    37501 agttctagta tcataacttg ttcaattaga ggatttaaac agctttttgt gggctgtttt
    37561 ttcttttata aaaaatgata taataaatta tgagatgcgt atttattgct tattctcaca
    37621 tgcttgtctg tccaattatt ggactagtag gtttaatact tggggtaagg gaaaaagata
    37681 ggttttttat ggcattaaat gtccttttta tcttattact tcctatagca atgtttgcta
    37741 gtcatctagt aggatctctt taagtaagat aataagttta gaataaaaat ttgtaaataa
    37801 ttttaaaaaa gctataagtt tatccactta tagctttcta tctctccact tcctttccat
    37861 aataattttc atagtttttt ctatactgaa caaggtcaga aaattgttct ttattcaaag
    37921 aatactcttg cataagggtg ttcttttttt cttgcagttt atcgagcttg gatagtattt
    37981 cttttgtatt tggtagctta ttataatttt ctaagatttc tttagcggct attttataga
    38041 cggaaagttc gctataatac tcctcttcaa attgcttatc ttcaggattt ttcttgtggt
    38101 atttatatat ttcacgatac ttatttatag tataaatatt ttccatatct ttggataaac
    38161 tcttcatctc agtttcaaat ttttttattt tatctaataa gtcttgtcta tcatcagcag
    38221 attttttgat cagatcatcg agctgggtaa tggaattaat gccttgttct cttaatttaa
    38281 ttattgaatc tgccattgtt ttgatattgt gttttcttgc ccagacttcg taacctttag
    38341 aggattgtgc tttttcatta gtagatatat caataacatt tcctactcgt tttttaatag
    38401 gattagcttt atttattata gctaaatcta ttctttcttt gatcttttct tcagtataat
    38461 cttctccgat agtcttagct cttgtaaatc ttttcttatc tttatgacga aaagcaatgt
    38521 gtttaccaaa cttaatttca taatcaagag atttcatatt ttctaaaaat tcttcccacg
    38581 agttagactt attaatcact ctatctatat caaattgcag tttagacttc caagaatttc
    38641 ctttcttgtt ttggtcatat tcgtaccaag atttaccagc agttttatat tttctcttgt
    38701 aagcttcata gtatttatca atgactgaaa gcttatttgc tttacataat tcatcacttt
    38761 gatacctgat tttgtggtaa gattttttgt tagattggta gcatttgcca gtcttgtaat
    38821 taacattatt aaaaataata tggttatgga tatgccctct atctatatga gttgcaagaa
    38881 caaattcata attttctttt aaaattttct tacataattc cattccaatt tcgtgagctt
    38941 ttataggatc aacctctcct ggtagaaaag attgaattaa atgtctagcc aaaactgtac
    39001 ctttagtatc attatcttct cgtgttttca taaattgaat atgggcagta gatggatgac
    39061 atttgaatga agataccaag attttttcat cagttttttc actcttagtt atatagtcta
    39121 ttgccaaatt tagagttgat tttataggat gtatttttgt aattgccata ctaatcacca
    39181 gaactttctt ttgatttatt aagaagtagg gaatggatct gccatatttc tttagataat
    39241 ttttctatct gcttattcat tgattcaatt tcatttttgt aaataacacc agttgtatta
    39301 gtcgcttttg caatctggtt tatattattt gttgcatttg aaagtagcca ttgtaggttt
    39361 ctgaatggtt ctaaatccac tacataaatt tctttttcta atacacattt cctaagaaag
    39421 tgggacatag ttttacaatt agcaagtttc attttctttt caaatatttc tttttcttca
    39481 tctgttaaat atatttttag ttgattattt ctttttctat tatccatagt atatctcctt
    39541 atcataaaat attggggtct tagggttctc cctaacaagg taaaattgat aaaaaaaaga
    39601 agcagtccat aaaggttctg cttcatcaat ttttcgtgag tgggtactca cttactgtgc
    39661 ttgctattaa agttataagc attaagcgta tattaagtta ttcttctaat tttttagtat
    39721 cattttctag ttctaagaac ttatcaaaat cacttttgta aagtctatct tgtataattc
    39781 tatatttttc aaactcactc tctgcgtgct ttttagcaag agctgcagac acttttcctg
    39841 catcgtttaa gatttcttta tcccataatt gtaaaaatcc atttaatctt ttttcccaat
    39901 cttccatagt catagggata tgcctttctg cttgtagttc tgccatgtcc aaatatgatg
    39961 aaacaattct ttgcatttga tttaattctt cttcatttag ataatttttt gcaacaacta
    40021 catcatattt atgaattttt gaatctggag atccttccca agtagtaagt cccatatttt
    40081 tagttttgtg gttggctcta tctacaatta attcagctgc agtttttcca tgaattgcat
    40141 agtgcaattt gttttgaata gctgcaaaaa atctttttgt tgcttttgca gatggatcat
    40201 agtctaaaga agtggcataa atatctgtga ttttttgata gaatcttctt tcagataatc
    40261 gaatctcacg aatttttaca agtaattttt cgaaataatc cttggtaagt tttgtgccag
    40321 aattcttgag tctttcatca tccattgccc aacctttaat tgtaaaatct tttacaattt
    40381 ggtttgccca ctttctaaat tggacagcac gttcgttatt tactttaaac cctactgcaa
    40441 taattgcttg taggttatag tgttttgtat tatatgattt tccgtcgttt gcagttatta
    40501 agtatttctt aataactgaa ttttcgtcta gttcgttatc gtcaaatatt ttttttagat
    40561 gctgatttat tgccgataca cttacatcat aaagagctgc catcattttt tgagttagcc
    40621 aaatattctc atcttcatat ctaatttcga tagcttcttg atcatcacca tttgctgcaa
    40681 caaaagtcaa gtattcagca gcagaggacc taatttgaag ttcttttttt ttctgatttt
    40741 cgtctttatt tttatccatt tctctactca taatttcctc caagtataaa tttcattcta
    40801 cctttaaaca ctggaatact aatcaagaat acaattacat aatgtataaa ggaatttatc
    40861 atcatacttt ttgttattgg taattgatga taagtttgac ctattatttt aaaagcggct
    40921 agagtgtttg ttataaaatc aagtgccaac catagggcga ctgatgagcc tataaaagca
    40981 attatatagt ttaaaaatct gctaaccttt ggtagctttc gatttattaa aactagcaat
    41041 attccataaa ttattactac tgtaattgaa aggggaatag ctaatttgct atctagttta
    41101 tcttttatgg atatgtaaaa tcctaaacct acaactataa aatcaattaa aaatgctgaa
    41161 atttttacag agtaggtagt gatgagataa tagaaaacta ttccagaaag gattaataaa
    41221 aaatatcctg caataaaaat tcccatagag tctcctaata ataatcatca tgttcagggc
    41281 gataattttt aagaaaatct ccctgaggta tattaacatt aactggttta ttaaacttgc
    41341 ccatttttgc taactcagaa atttttaaat ttagtaaatt tatatctacg cctaactgtc
    41401 cagcgatttc ataatcacaa acttgatcat tgatattatc taggatatct tcatcactta
    41461 ttaataaatg agctgcaaaa atattagctt cagtttcaaa tttatttgta gggtttagca
    41521 ctgtttggtc atggaaagct ccgccactca tacaataatc tctgtgaagt tgatcgtgac
    41581 ctaattcatg tgctaatata gtctttctat taaaatttgt gttgctactg ataaaaataa
    41641 atctgttcct ttgaatataa tggtacattc ctaaaagtat ttttgtttca ggtagatata
    41701 ccaggttaat attcaaagct tctattaatt cgataggatc tcgtgtctta tattttttta
    41761 taagtcgatt aaccttatca tatatatagc gattcatgct cataaaatca cctaatcttt
    41821 tttcttacga ccgtatttct tgttttctct tttagcctcc caataagcac gagtaatagc
    41881 ttcaaaagca gcatctttgt cttcgtcaga aatttctcca ccagcaaata aagagcttag
    41941 accttctgtt aatgctctag ctttttctaa ttctcttttg ccacccatgt tataaactct
    42001 atttaaaaac tcgtcacttt cttctaaaag ataattgtaa tcacagtcca taacttcagc
    42061 tatttttttg taaacctcga catctcttgg gtatctttct ccgtcttcat aatgtacaag
    42121 agttcttgta cttattccta tcatttttgc aaaatctgct tgacttaatt tttctttttc
    42181 acgaaaatcc tttaatctat ccgcaaaagc cataacttta acctcctgta ctaatgtgca
    42241 tttataactt ttaatacgaa caatagtgct tgaattattt ttcaatttga gatataatac
    42301 aaactgaact tatattcata ttatagcaca aacattcaag tttgtaaata agttgtattg
    42361 gggtgattag attgagaata agtaaaactt taaagaatat aatgaacatg tatgcagata
    42421 gcgacttgaa atttgaagaa attagttcag ctgcaaaact cattttaagt ttatatagac
    42481 aagttacttg ggcagtagat agcagggcaa attttatgat gtttgagagt aaagaaaact
    42541 atgggtcaac ttcagaatct gcttacttgt atctttctac atttgctcca gaaagagttg
    42601 aagaaaagtt taataataga gtttccaatg taatggatag taagcttata cttttaataa
    42661 tttatgatgc ctgtgttagg ttaaaagttt atccagaata tggagaaatc tatcataaga
    42721 ttatttataa ctactacatt tctgaaaaaa agattactga tgaagcttgt atgagaagtg
    42781 tatctttaga gagaactgtt tattatcaaa gaaagaagga agcaattgca ttggttggtg
    42841 taataatttg gggatatact ttaccgactg ctattagcca acttaaagat ggtcgtagca
    42901 ttgaagaaat aatgaacatc taaggactta atttatgacg aacttattgc gtactatttc
    42961 cgaatgaaaa aagtaccata tacgaatttt atgtgtactt aagtgcatat ataatatcca
    43021 tgatgggtga tttgcaccta aatttaatat tggcatttat tgactgaaag aatttatttt
    43081 ctttcggtct ttttttatgc ccaggagagt atatgcatag aattagaagc cctccttgtg
    43141 tgaatttcat ttttatataa cagaaattca agtcaacaag gaggaaaaat taatggacaa
    43201 agaatattat ttatttgtag aagggaagaa agtagttgtt agcaaagagg tatatcttgc
    43261 ttatcatagt gaattgaata aagagaaata tcaaatgaga agagacaggt taaataactg
    43321 tttctttttt tgttcctatg atcatgatgg taattttgaa gaaaatttag aagatctgga
    43381 atttgatgtt gaaaaaatta tcgaaacaaa ggaaatgatt gaagaagtaa gaagagctat
    43441 ttataaactc aatcctgttg aaagagacct aatagaaagc cttttttata aagaagaaac
    43501 aattagagaa gtagctgcta aactgaatat ttctcatcca gccgttatta aaaggcgtaa
    43561 taaagtctta gaaaaactaa aggaaatgtt ggaagacttt tagatgacaa ttgccaagag
    43621 ggtctaattt tcactgttac ttatacagtg ggaattggac ctttttattt aaccaaattt
    43681 atttttgaaa attggttacc aagaaagact tcttttcact gttaagtata agagggtaat
    43741 tttaaacaat tttgtttcat caagataagt attttctgat ggtcaaaatt taaaaagatt
    43801 aataactctc gataaatttt gaaccttaac aattgaatag accaagacaa gacgttaatc
    43861 atttttggag cgtgataacc tatccgccaa gatctttctg ctgaataatt cggcaaaaca
    43921 agtactgcta agctaaaagc aagggaagaa gaaagggagc gataagtaag agtttgaata
    43981 tagggaggga taccctattc gctatgaaga aaatgaggat aatgatactt ctaaggttga
    44041 agccggctca tcctgaacag aggcggaggt gagattccta tgttgctaat ccaaggcact
    44101 tgtcaatgtc aaaaaactta aatttacata ggaggttatt atgaaagcaa taaagattta
    44161 tagcatgaga gttgctatgt tgtgtaggct ttatgatctt aaattaatta atgataagga
    44221 atatgcaaaa ataaaaaata gaatagaaaa tgattataag aagagagata gaaagtagtt
    44281 aatcttgtga tataataaca ctgtagaaag atacaaaatg ggaaggaggt aaaatgaata
    44341 ctaaagtaaa attaataaaa gcttcaaata caggagctag aaatagaaat gcactacgtt
    44401 tagatttaaa acgtgttgca gcatattgtc gagtaagtac agatagtaaa gaccaacttg
    44461 aatcatataa atcgcaagtt gattattaca caaatctaat aaaaaataat aagaactgga
    44521 ctctggctgg tatatatgca gatgaagcaa caacaggaac aactgctact aaaagagcag
    44581 atttcatgag actaattagt gattgtcaaa atggagatat agacatgata attactaaat
    44641 ctatatcaag atttgctaga aacacattag atactttgaa atatgtaagg cttctaaagg
    44701 aaaataatgt tggtgtagta tttgaagaag aaaatataga tactttgaca atggatggag
    44761 agctattact aacaatatta agttcagtag ctcaacaaga agtagaaaat acctcagccc
    44821 atgtaaaaaa aggactgaaa atgaaaatgg aaaaagggga acttattggt tttcaaggtt
    44881 gccttggata cgactatgac cctataacaa aaagtatctc tataaatgaa gaagaagcca
    44941 aaattgttag atatatcttt aaaagatatt tagaaggcaa tggtggttcg gtcattggta
    45001 gggaactaga agaacaagga tatctcaccc ctagaggtaa aacaaaatgg tctgatacta
    45061 cagtgttagg ggtaattaag aatgaaaagt atattggcga tatactaatg ggaaaaactt
    45121 ttacagttga tccaataaca aaaagaagac tagcaaattt tggagaatct gataaatacc
    45181 acattgaaaa tcatcacgag ccaattatat caaaagaaga ttttgaaaaa gcacaggaga
    45241 ttagactcag gagagcacaa aatagaaaca ccattgctaa taaggatagg aagagagaaa
    45301 aactatcaag gcaatacgct ttttcaagta tgttagaatg tggattttgt ggagagatac
    45361 tttcaagaag aacatggcat acaagttcaa tttataaaaa aattaactgg caatgtgtaa
    45421 agtcaacaaa aaaaggtaaa aaatattgcc ctcattcaaa gggaatacaa gaagcagcaa
    45481 tagaaaaagc atttgttgaa agctataggc aattatgcca tgcagattca acagtaatag
    45541 atgacttttt aaaaattgtt gaagaagaaa taaatgataa tacgttagtc aaagatttga
    45601 aaaagttaga aaaccaatta aacagaatca ttagtcaaga aagaaagtta gttgatcttc
    45661 atttagaaga tagtatagac gaagaagttt atgctaaaaa gtataaaaaa cttacaaagc
    45721 aaaaagaaga attactcgat gaaaagaaaa cattggaact aacgataaaa gatgaagact
    45781 ctattaaaga aagattaaag caatttaaaa aggtcttaga gaataaagaa attatagagg
    45841 aatttaacag aacagtattt gaaagcatag ttgataaagt cgtggtggga agaattgaca
    45901 aagacggaac agttcatcct tatgacttaa cattttactt caaaacagga gttaaagata
    45961 gtcaagattc taataacttt aaagataaaa gaaaaaatgc caaagacaat gacattaata
    46021 aattgtgttc ctacaagaat gacgaggata aaaaattatg ttcccaatca aaagacaacg
    46081 cattgtgaga ctgtagttaa acttattaga gaataacagg gtttcagact tttatagtgt
    46141 gtcttaaaag tagatttgct accataatta tttttgggtg gcaaatttat tctacaatga
    46201 tttcaaaaat atttaccgtc tggtttctca tgttattagt tacatgtaaa tatgtatcca
    46261 tagttgttga agttttagca tgtccgagta tatgctggat atcttttata ttagtaccat
    46321 tttctaataa catagtatca gggtttttaa aataaagtgt gtattcttct aaagtagtga
    46381 taattaaaat atcaaatatc actatacaaa ggaaagtgca cgctttttat gtttaacaaa
    46441 aacgaaatat taaaaaactt attgaagaat atgatgtcaa aacaactaca gatattcaag
    46501 atatgctaaa agatttattt acaaatacaa ttcatcaaat atttacattg tcgaatttta
    46561 acggtttaaa cataatatat tgactgatat aataaaatca tagaatattt tagggggaaa
    46621 tagattatgt ttaagaaaaa gttaatagct gttgcaatga gtataactat gattagtgta
    46681 gggagctttt cgtatgctca ttcaggaaga actgattcat caggaggtca tcgtgataat
    46741 aaaaataaat ctggattagg aagttatcac tatcattgtg gtggttatcc agctcattta
    46801 cataataatg gtggttgtcc ttatactgga ggaggaagca gttctggaac aacaacttcg
    46861 gttaataatg aagaaaagca aaagaggtct gttggagaaa aaggatataa tcaagggtat
    46921 gaagatggat ataaaggaaa ttatagttca tcaaattata gtggagatta tagtgataca
    46981 tatgaatcaa agtactcaga aggatatgaa aaaggtaagg ctaaattaga agaggaagaa
    47041 aaggtggcta aagagactgg atataattta gggcttacag gtgctaaatc taataataca
    47101 tatgaaaaag aagttttaaa aaatgcttat gataccggat attcaaccgg atacaatgaa
    47161 tataagacta aaaagataga agaatataaa gctaaaggga tagaggatag caataaagat
    47221 aaagaaaaaa tgacatttga agaaaacata gattctgaat ttatagatgc ttataataat
    47281 gcttatgacg aaatacaaga acaattaaaa aatgattaca ctactcaagg atttgagagt
    47341 gctatcaaag gagaaagatt tgacacatca actataggta atgttaaata tgctaattgg
    47401 tttaaagaag gatatgataa tggtaaggtt aagttaccta aagcaaaaga aagtgtatat
    47461 aatcaaggtt acaatgaaga agattttagt ataccagatg aaatgaagtc tattgaaact
    47521 aagttaaaag gtgtatatga tgaaggttta gaaaaaagag aggaagagaa aagtagaaat
    47581 gctacttatg gggttggagc tggaatagca gctgtagttg ctggagtagt atataagaag
    47641 aaaaaacgta aaaagatata gatgctagat ataccaatga tgacaagtgt ataacaaata
    47701 taattttaag tataaatatt taaaatatag aagggaaggt tatatctatg ggatttaact
    47761 ttaggaaaag cataaatcta ggaggaggac tcaaattaaa tttaggtaag aagagtgtag
    47821 gtataagtgc tggtgttaaa ggtgctagag tgtcagttaa ttcaaaagga agaaaatcag
    47881 ctacattgag tatacctgga actggaatat catatacaaa aactagtaca aagaaacgta
    47941 aacctaaata aatatttgat atactaagaa atagactgtt acaaatagtc tattttttag
    48001 tatatagatt taaaaagtga caaaattttg aaatataaac taatttcata aaggaaaata
    48061 ttcttttatg taaaattata atatttaagt aatattataa aatttatagg aggatttcat
    48121 tatgaaatta agcaaaacac tattggcaat agggatgtct gtttcattat tgattgctag
    48181 ttgtccaaca tcaaacgctc ttagttctat taattcaata aaaggtacaa ataagtatga
    48241 aacagcaggt ttaatagcag ataaacaaaa ttatgatatt gcaatactta ttaattctga
    48301 aaatggatta tctgatggat tgtcagcaag tggattgtca ggagctaaaa atgccccaat
    48361 attgttaact aagaaagata caatcccttc agaaacatta aaaagattag aaaaggtaaa
    48421 agaagtatat ctaattggag gaaaaaattc gataggagca tcagttcaga aaatattaag
    48481 tgataaaaaa ataagcataa atagaataag tggaactgat agaatagata caagtcataa
    48541 agttgcaaaa gaaataggaa gagtaagtac ggttaaaaaa gtaatattaa ctaatgcttt
    48601 taaaggcgaa ccagatgcta tgagtgttgc ttctatagca gttagagata aatctccaat
    48661 agtattaact gatggaaata ctacaagttt tgctacagat ggattagaaa cttatgcaat
    48721 tggtggaaaa gtcagtatga gtgataagtt aataaatgaa actaaagcaa caagaatagg
    48781 tggagtagat agatacgata caaataaaca aataataaat aaattttata atggctcaaa
    48841 agaattttac atagcaagtg ggactgattt agtttattct ttagttggtt ctacaattgc
    48901 acaaaaaaca cctatagtgt tagttggaaa tggaagtaat aagagtatat taaaaaatgc
    48961 aagtaaaata actgctattg gaaatattga tgatgttgtt ataaaataat gtttaaatat
    49021 aactaataat gttggggatt caaatacagg tattgtaaaa gatactaatt caaataatac
    49081 gaacaaacca agtaatgagc ctagctctaa taatcctgga ttaactgata aaagtacagt
    49141 atatgtaact cctaatggaa aatcatatca tctaacaaaa aattgttcta cactaaaaag
    49201 aagtaaaaca ataaataaag taacattaaa acaagctaag tcacaaggta aaatagaccc
    49261 ttgtaatgtt tgtgtaaaat aatgtattag ccaaatatat attaaaaaag acaattaatt
    49321 aagattgtct tttttattga agaaatataa atttatatta tgtattatta aaaagaaaat
    49381 tattaattat aaaaaataat aataaagacg ataagtatta aaattttatg tttccaatat
    49441 ttatgatata attaatatgg caaggaataa atatttgaaa aagctatgag tggtgtttcc
    49501 atggaagttt cttcactttc ttatgagagg aggtgaaaac tatggaaaat ctaatgatga
    49561 gtattataac tggtgttata gccagttaca tttacgataa attaaagagc cactctgagc
    49621 gaccaactaa gagtggctgg gaacttaata taaagttcca gaaaagtaaa tcttcaaaat
    49681 aatttgttga aggaaacatc actcaaagtt aagtaaaata tgtttccttg cttttattat
    49741 atcacaaact aaaaatatta acacaaaatt ttgtgaatat atacttatta ttgttctaaa
    49801 aaaatatgta aataattgat ttgatttcat agaattattg ttgtaatgtt tagttaaata
    49861 tacacaatct caattaaaga agataagtac tataaattca tatcaaaaaa atatataaac
    49921 ttttaagtta taattttata aaaagtcttt tagtatcatt atttcaagag gaattaacat
    49981 atgaaaaaat aacttcatta gaaaagtgga taaaaaactg gtaagaagat gactaaagat
    50041 tacatatact attacttaaa ttaaaaattt aatataaaca acacaagata tatcaattat
    50101 tctaaagtta agtagtctta ctgaatcatc tttgggaata attgtttcaa tgtctagtag
    50161 aaataccact tgtttataac atctttagct actataatcg aaatatgttt ttagtttttc
    50221 acagaacaat tatcacatag actagaggtt tttaggaatc acttatcttt tttatacaaa
    50281 aaggagataa ttcaaatttt tattttgata tatccccatt ttgtgattta taataatttt
    50341 tgtccttatt ttaaataaaa catagattta agttctatag atacagggct attatcctca
    50401 ttagtttcca ttatatcaga catataattc caccattttt tgcagattgc tgtctctgaa
    50461 cttttatccc atagtttggc atctttaagt tctatatatc catataaata attagtttct
    50521 tcatctagaa aaatagaata gttactacca ccatattcat gaatcatatc tatcatctca
    50581 gaccataatt catcatgacg tttcttgtat tcattttcaa atcctttaaa aagcttcatc
    50641 ttgaaacatt tgcgtattgt attcataaaa aaatacctcc taaattttaa gtatttacct
    50701 ataaatgtat tttaaaacaa aaaaaggtat ttttaaatgt cataatttaa cattattact
    50761 gtcaaaaact aatatgatac aattagataa agaatatttg taatataatt taaaactgta
    50821 ataaagtata gctaaatctg gggggatata aatgaaagat gaaacgctag aggatatact
    50881 taaacaaaaa acacaagcag aaaggtacat cttagaatac atagttacta agaatgtaaa
    50941 aaaactagat aataaaaaaa tagtgtctat attgcatact attttatgtt gggaagaaat
    51001 aaatggaact atagtactaa cagataaaaa tatactttct ttagatgaag acattataat
    51061 atctaaacat cgtagattta tagatatacc caaacataaa cataacttta tagagtttca
    51121 tctaatgagt taatatataa ttttttatca ggaactatac acaaaggaaa aagatgtgat
    51181 aattattata tatttaatgc taaaaataat tttaaattga aacaactagt agttgaacta
    51241 actaaggagg tagctcatga gacaatatat tcatgataag ttgagggaaa taacagaaga
    51301 agaaaaaaat atattagaag gaaattatat aatagataaa agtatttata ctgataattc
    51361 tcaatttata atagatagca acaaattatt gaatatagat gagttgatac atataagaaa
    51421 acatacaaga tttgcacaat ttccaaaaca taagcataat tatatagaat ttaattatgt
    51481 ttatagagga aagttagtac aaactataga tgaatataaa attaatttaa aacaaggaga
    51541 attaatattt ttaaatcagc atgttattca tgaaatagaa gctagtgacg aagaagatat
    51601 aataattaat tttataataa aaccagagtt ttttgattat attatatctt tgttggaaaa
    51661 tgataataaa ataatgaact ttttaatgac tacattatat actaattata atcttggaga
    51721 atatatatat tttaaagtat ctgagaaaga agagattcaa gatataatag aaaaaattat
    51781 aatagaattg tatgaaccaa gtgtggttaa taaggtaaag attaaattat tagtaggatt
    51841 attattagta gaattagtta aaaattctga agatgtagaa aatcatgcag tagataatta
    51901 tgaaaagatg atgattatag aaatactaaa atatattgat aaggactaca agaaaggtag
    51961 tttatctgaa attgcaagta atttgaatca aggtgattat aaaataagta aactagtaaa
    52021 aaaacatctt ggatatactt ttaaagattt agtgcaagaa aaaaggttaa gtaaagcatg
    52081 tgaattatta gtatctacta atttatcaat agctgaaatt atagaaaatg taggttatga
    52141 aaatttaact tatttttata aaatatttaa aaataagtat ggtattacac caaaagaata
    52201 caaaaaaaat ataaaaaata gtcaatagta aaattagaat ctataaaata gattcttttt
    52261 tattattaaa taaaccattt taatagctct gaagatatta tattttgaaa attattattg
    52321 agaataaagt tatattgcaa attaggttaa taaatatgac aaatttagat attaaatgaa
    52381 tatactaaca tcttgtataa ttcaattaat aaataaatct aaggaggaaa agtcttgaga
    52441 tactatttag caattgatat aggggcatct agtggaagac atattatctc ttatataaat
    52501 aatggaaagt tggaaataga agaagtatat agatttaaga ataatttgat taaaaaagat
    52561 ggtcattttt gttgggatat atcaaagcta ttttctgaaa taaaaaatgg gataaaaaaa
    52621 tgtataaaaa taaataaaat tccagtaagt gtggctatag acacatgggc tgtagatttt
    52681 gtgttacttg atgaaaaaga caatatatta ggtaactgtg tatcatacag agataataga
    52741 actgatggaa ttatggaaga agcctttaaa ataattgata aaaaggaact atatttaaaa
    52801 acgggaatac aatttcaaaa gtttaatact atatatcaat tattagcaat aaaaaatcaa
    52861 cagccagatt tattagaaaa ggcaaaaagc tttctaatga ttcctgatta ttttaacttt
    52921 ttattaactg ggaaaaaagt tacagaatat acaaatgcaa caactacaca attagtaaat
    52981 acaacaacaa ataattggga tgaagaaata ataaataaac ttggatttga caagatgtta
    53041 tttgctaaaa taaaaactcc caaaacaata ctaggtagtt taaagaaaga attagtagaa
    53101 gagttaggat gtgatttaga agtcatttta ccagttactc atgatacagg ttcagctttc
    53161 atgtctactc ctgtaaaaaa tagaagcatt ttattgagtt caggaacatg gtctttatta
    53221 ggagtagagt tagaaagacc aaagtgcaaa ttagaggctt tagattataa ttttactaat
    53281 gaaggtggat atgaatatag atatagattt ttaaaaaata taatgggttt atggatgata
    53341 caagaagcta gaaagtgtta tgacagtaag cactctttta cagaactagt agagcatgca
    53401 agactatcag aaggatttaa atcaatagta gatgtaaatg atgatagatt tttaaatcct
    53461 gaaaatatgg tacaagaaat aataaaatac tgtatagaaa ctaatcaaac agaaccacaa
    53521 acagttggag aagtagcata ttgtattttt aacagtttag caaaaagtta tagtaaatct
    53581 ataaatgaaa tagaaaaaat catagaagaa aaattagaaa ctataagtgt atttggtgga
    53641 ggatgtcaaa atgaactgtt aaatgagctt atagcaaaag aaagtggtaa aaaggtatta
    53701 gcaggacctg ttgaagctac agcattaggt aatatagtat gtcaattaat tgctaagaat
    53761 gagctaaatg atttagaaca ggcgagagat ataataagaa attcatttga tataattcaa
    53821 tataattaat ctgaaaaagg agataagtga tggaattaaa gcaaaggtat gaagtagcta
    53881 aaaaagaata tgaaaaatgg ggaataaatg tagaggaagt attaagagtt ttatctaaag
    53941 ttaaaatatc tattcattgt tggcaaggtg atgatgtaac agggtttgaa ggaaatcaac
    54001 aaagactatc aggaggaatt gcatctacag gaaattatcc tggaaaggct agaaatcctc
    54061 aggagttaag acgagatttg gataaggctt taagtttaat accagggaaa cataaagtta
    54121 acttacatgc tatatatgca gaaactggtg gaagctttgt ggatagagat gagctaaaac
    54181 cagagtattt tgaaaattgg gtaaaatggg ctaaagaaag aggattggga ttagatttta
    54241 acccaacaat attctctcat ccaaaatcaa gtgatgggtt aacattgtca cacccagata
    54301 aaaaaatacg tgatttttgg ataaagcatt gcatagcttc tagaaaaata ggcgaatact
    54361 ttggaaagga gcttggtcag acttgtttaa caaacatatg gataccagat ggatacaaag
    54421 atataccaag tgatagatta ggtcctagaa gacgcttaaa ggaatcacta gaagaaatat
    54481 taaaggtaga gataaacaga gaatataatt tagattgtgt cgaatcaaaa gtttttggat
    54541 taggtgtaga atcttataca gttgggtcaa atgagtttta cttaaatttt gctagtaaaa
    54601 acaacataat ttcattatta gatacagggc actatcatcc tacagaactt gtttcagata
    54661 aattatcatc aatgctatta ttttcagata aagttgcact tcatgtaagt cgtccagtgc
    54721 gttgggatag tgaccatgta gttatattag atgatgaact aaaagaaata gccaaggaaa
    54781 tagtaagaaa tgatgctttg gataaagtaa taataggact agacttcttt gatgcaagta
    54841 taaatcgtat agcagcatgg gtaattggaa ctagaaatat gataaaagca ttgttatcag
    54901 ctatgttaat gcctcatgaa gaattaagaa aattacaaga cgaaggcgat tttacaaaaa
    54961 gattggctat aatggaagag ttcaaaacat atccaatggg agacatatgg aactattatt
    55021 gtaaaattaa taatgttgct gttaaagaag attggataga agtagtaaaa gagtacgaat
    55081 taacagaatt attaaataga aagtaggtaa gggtatatgt ctataatgga aatgaacttt
    55141 atcaaagatt ttatgaaaat aacttatgat gcttggttaa agggatggca tgagcgtaat
    55201 ggggggaata taacgtatag attaacacct gaagaaatat ctggaataaa agaatttata
    55261 acagaagaaa tagaatatat tccaattggt gtaacagtcg aaaatttagc taatgaatat
    55321 ttcttagtta caggaagtgg caaattcatg agaaatattt ctataaatac tgttcaaaat
    55381 gtaggaattg ttaaaataga tgaaaaaggt gaaaattatg caatagtttg gggattagat
    55441 aaggctaaac caacaagtga atttccatct cacttaatga gtcattctat aaaaaaagac
    55501 aaaacaaatg gattacatag agtaataatg cattcacata caactaatct catagcatta
    55561 acttttatac tgcctcttga gggtaaagta tttacaagag aattatggga gatggctaca
    55621 gaatgtccag ctgtatttcc agaaggaatt ggaatcgtac cttggatggt gccaggtggg
    55681 atagagatag caaaagctac acaaaatcta atggaaaaac ataacatagt aatctgggct
    55741 catcatggaa cgttctgctc aggagaaact ttggacttaa catttggtct tatggataca
    55801 gtagaaaaat cggctgagat attagtaaaa gtaatatcta tgggagggaa aaaacaaaca
    55861 ataacaggag ataactttag agacttatca aaaaatttta aggtttcaat atcagaggat
    55921 tatttgtact agataagata aaagataaac aaagctatga taacttatta tgtacaatta
    55981 ataaaacact atgagagagg aggtgattaa aagatataga aagtaaattc acttaagaaa
    56041 atagtttaag aataaactgg agtttataat aaaatattca acaatatatt tatatatata
    56101 aatatattgt tga
//
LOCUS       DAMJXI010000209        43074 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.guided.031, whole genome shotgun sequence.
ACCESSION   DAMJXI010000209 DAMJXI010000000
VERSION     DAMJXI010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 43074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43074
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.guided.031"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            246..863
                     /locus_tag="PC465_003912"
     CDS             246..863
                     /locus_tag="PC465_003912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDF2651116.1"
                     /translation="MCKKTYLLVVSMLIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIMTPQQAMEIALKEQNG
                     IVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            971..3502
                     /locus_tag="PC465_003913"
     CDS             971..3502
                     /locus_tag="PC465_003913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HDF2651117.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNIKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            3936..4637
                     /locus_tag="PC465_003914"
     CDS             3936..4637
                     /locus_tag="PC465_003914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HDF2651118.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            4687..5769
                     /locus_tag="PC465_003915"
     CDS             4687..5769
                     /locus_tag="PC465_003915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2651119.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFMNHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIVGNL"
     gene            6030..7130
                     /gene="vanG"
                     /locus_tag="PC465_003916"
     CDS             6030..7130
                     /gene="vanG"
                     /locus_tag="PC465_003916"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HDF2651120.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNNDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            7127..7933
                     /locus_tag="PC465_003917"
     CDS             7127..7933
                     /locus_tag="PC465_003917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2651121.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            7951..10089
                     /gene="vanT"
                     /locus_tag="PC465_003918"
     CDS             7951..10089
                     /gene="vanT"
                     /locus_tag="PC465_003918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HDF2651122.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGVKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            10403..11023
                     /locus_tag="PC465_003919"
     CDS             10403..11023
                     /locus_tag="PC465_003919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDF2651123.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(11189..11725)
                     /locus_tag="PC465_003920"
     CDS             complement(11189..11725)
                     /locus_tag="PC465_003920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDF2651124.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(11838..12512)
                     /locus_tag="PC465_003921"
     CDS             complement(11838..12512)
                     /locus_tag="PC465_003921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HDF2651125.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            12715..14589
                     /gene="asnB"
                     /locus_tag="PC465_003922"
     CDS             12715..14589
                     /gene="asnB"
                     /locus_tag="PC465_003922"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HDF2651126.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            complement(14681..16117)
                     /locus_tag="PC465_003923"
     CDS             complement(14681..16117)
                     /locus_tag="PC465_003923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDF2651127.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKGSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYDSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIVFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWM
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVNRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESNLVKIFANNFIEIVN"
     gene            16446..17024
                     /locus_tag="PC465_003924"
     CDS             16446..17024
                     /locus_tag="PC465_003924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2651128.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            17063..17641
                     /locus_tag="PC465_003925"
     CDS             17063..17641
                     /locus_tag="PC465_003925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2651129.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            17727..18356
                     /locus_tag="PC465_003926"
     CDS             17727..18356
                     /locus_tag="PC465_003926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2651130.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            18346..21105
                     /locus_tag="PC465_003927"
     CDS             18346..21105
                     /locus_tag="PC465_003927"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HDF2651131.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGRDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     PKKTA"
     gene            21192..22754
                     /locus_tag="PC465_003928"
     CDS             21192..22754
                     /locus_tag="PC465_003928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HDF2651132.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAMDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGAIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDVHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            22755..23891
                     /locus_tag="PC465_003929"
     CDS             22755..23891
                     /locus_tag="PC465_003929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HDF2651133.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            23955..25031
                     /locus_tag="PC465_003930"
     CDS             23955..25031
                     /locus_tag="PC465_003930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HDF2651134.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNSHFITGILIPKANSELIENCIEALDSMNLQDMYVI
                     PIVETKEFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFADALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            25009..26247
                     /locus_tag="PC465_003931"
     CDS             25009..26247
                     /locus_tag="PC465_003931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HDF2651135.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGIRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELDCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMASKESLKNEKEKILFLGTEEFMYIPMLFAKEKENKYDIYYHST
                     TRSPIINIDKNNYPIKSKFMLKSFYNIDIQNYIYNIDKHNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            26301..27389
                     /locus_tag="PC465_003932"
     CDS             26301..27389
                     /locus_tag="PC465_003932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HDF2651136.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYIRSKYNISLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNVKFKKYFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLIGKNDFHGAKFYRHLKDKDESMNYIKTIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFIL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDI"
     gene            27417..28208
                     /locus_tag="PC465_003933"
     CDS             27417..28208
                     /locus_tag="PC465_003933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HDF2651137.1"
                     /translation="MIVFSDLDRSIIYSNKFLNADSKYTNIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKSDYEPIESMIHKFKDYLNVDGITNFKVAEDTFFYIVVDLSRFNLDSIKEYTNI
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAVGDSIMDYGMLNISNK
                     SYVLKHGDINKNEIENSFISSSFNGMSGTEEILSNILDENCLLNI"
     gene            complement(28323..28877)
                     /locus_tag="PC465_003934"
     CDS             complement(28323..28877)
                     /locus_tag="PC465_003934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDF2651138.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIVVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTQKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDEVCISVWAMTPPSF"
     gene            29073..30275
                     /locus_tag="PC465_003935"
     CDS             29073..30275
                     /locus_tag="PC465_003935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HDF2651139.1"
                     /translation="MKSFVSPDNIWVLWAVVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGITEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            30351..31331
                     /locus_tag="PC465_003936"
     CDS             30351..31331
                     /locus_tag="PC465_003936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HDF2651140.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISENKINILIGLE
                     GLSHIGRNIDLLDYFYKEVGARHASLTWNEQNELATGCLGDENRGLTEIGKKAVNKME
                     KLGMIVDVSHLNEKSFWDLMSVASKPVIASHSNARSLCDAKRNLTDNQLKEISNTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NASVPSVDGLESTHTAQNIVVELENRGYKKKDIELISSGNFYRLFKYILK"
     gene            31579..32532
                     /locus_tag="PC465_003937"
     CDS             31579..32532
                     /locus_tag="PC465_003937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDF2651141.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RIPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFTFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRANIWYTGLLGAIFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            32522..33478
                     /locus_tag="PC465_003938"
     CDS             32522..33478
                     /locus_tag="PC465_003938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDF2651142.1"
                     /translation="MKLSLNQKIYFVSILLFISIALFIIYGIDMNHLEYALSQRIPKI
                     FAMVLGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAMMIGASLLLYKMLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKAVKKMIILIAILVSISTALIGPMTFLGLLLANITREIFKTYKHTYLISGSMLIGM
                     ITLIIGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            33475..34230
                     /locus_tag="PC465_003939"
     CDS             33475..34230
                     /locus_tag="PC465_003939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2651143.1"
                     /translation="MIEIKNIFKRYKNKNVVDDVSFSIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRSLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVEKVG
                     RTDEIVNEKVLEDIYEMNFNIKNINGNRICIYF"
     gene            34322..35287
                     /locus_tag="PC465_003940"
     CDS             34322..35287
                     /locus_tag="PC465_003940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2651144.1"
                     /translation="MNKKAAIVAAVAIIGLVTVFALGGSKKNESKTSENSNNTIKITH
                     NLGETDVKLNPKKVVVFDYSALDTMDALGVAENLVGLPKASLPASLEKYKDDKYADLG
                     GLKEPDLEGIKSANPDLIIINGRQEDFYEQLSKIAPTISTSKDDKKYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFENKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDVKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
     gene            35765..37624
                     /locus_tag="PC465_003941"
     CDS             35765..37624
                     /locus_tag="PC465_003941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2651145.1"
                     /translation="MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVR
                     GASQRLTKLEMNHQPNDELIEYIDEILQELITGHGDYGLVITDCNEYNEDLLLLEKKW
                     EDLNIEIKKVRMKEQNNQLLSISEEFFSLANDTVFKIENFSKEKSNYLMTLIIIISII
                     GILACIILILQYSKKMVRLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICIHKDK
                     KFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRC
                     YVDKEDLVVRQRDVDNELINITNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANF
                     AQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHSQKI
                     NCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFV
                     QISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQKHLLEIIHDLH
                     ENGFTCSLDDFGKGYSSLSVLKDLPFDVLKLDSMFFKASLDKDKEKIVIKNIVHMLKE
                     LNITTVAEGIECKEQVEFLRDIGCDLVQGFVFYKPMPILEFEKILDKEFVYNS"
     gene            complement(37916..38515)
                     /locus_tag="PC465_003942"
     CDS             complement(37916..38515)
                     /locus_tag="PC465_003942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2651146.1"
                     /translation="MAIELKKGQKINLTKKENSNLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNTQGENLRIN
                     GNKIKDIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(38618..39415)
                     /locus_tag="PC465_003943"
     CDS             complement(38618..39415)
                     /locus_tag="PC465_003943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2651147.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(39528..39633)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(39725..40711)
                     /locus_tag="PC465_003944"
     CDS             complement(39725..40711)
                     /locus_tag="PC465_003944"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HDF2651148.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYLSKTNTDNTNYCLSEHD
                     IKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVAFVENKLIGIRHEENALRNTLDSIEINDYFLGADTDILVSGILGVK"
     gene            41195..42925
                     /locus_tag="PC465_003945"
     CDS             41195..42925
                     /locus_tag="PC465_003945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HDF2651149.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKK
                     VDEAEIELVE"
BASE COUNT        16593 a         4669 c         7276 g        14536 t
ORIGIN      
        1 caaaatgaac tttttagttc atgaggcact ctttttgtac gaaataaaat atatttttat
       61 tatttcaaca atgaaaaaga ggcttgtttc cattttgaga cagtataatt tttatgtaac
      121 tttaatttta gtaaatataa agttttaaaa ttgataaaat aggaggaatt tttaatataa
      181 aagggtaaat aaagggttta gagggcataa tatagaataa attaatatat ttaaggaggg
      241 tttttatgtg taaaaaaacg tatttattag tggtaagtat gcttatagcg ggtttattaa
      301 ctgcatgtag tgggagtcca actaaggatt caggacaagc acaagataat acaaaaaagg
      361 aggcaaatgc atcaaataac gctttaaaag atgaaaaaaa taatgaaaat ttaatggaac
      421 aagattttaa agtgccatac acagatgcaa taaacatatt taaagataaa tataaggatg
      481 ctgatatagt agatttaagt cttgagagag atttaaataa atttgtttat actgtggaag
      541 gtgtagatga taataatgaa tataagatga aaattgatgc taatacaaaa gatgtattag
      601 aagataaaac agaaaagttg gattcagaag atttaaatgg agttgctaga aaagaaaaat
      661 tagatttaaa tgacataatg acacctcaac aagctatgga aattgcatta aaagaacaaa
      721 atggaatagt taaagaatgg agtttagaca aagatttaga tgttactttt tataaaataa
      781 gaatagataa agataaaaat gaatatgaca taaaagtaga ttctaaaaag ggaactgtat
      841 tgaaggtaga aaaagaagat tagaagattt aaactatctt taaaataatt tcttttttga
      901 ataaattttg tttaaaatat aacaagcagg gtataaagag actaaataac tattttagga
      961 ggagtacggt atgtcattga aatcactaaa aataaaagaa aatttatatt gggtaggttc
     1021 gcttgaccct gatttaagag tatttgacat aattatgtat acaccttatg gaactactta
     1081 taattcatat gtattaaaag gaacagaaaa aacagtttta tttgagacag ttaaagataa
     1141 gcattttgac aattatattg aaagattaaa tgatttaaat atagattttg aaaaaataga
     1201 ctatattgtt gtaagtcata ctgaaccaga ccatgcagga agcgttgaaa agcttttgga
     1261 tttagctaaa aatgcaaaag tagtagcttc agaaacagca attaaatatc ttaaggaaat
     1321 cgtaaacaaa gactttgaat atgttgcagt tacagatgga gatacattat caattgggga
     1381 caaaacttta gaatttttct ctgtacctat gcttcattgg ccagatacca tatacacata
     1441 tataaaagag gataaaactc ttgtaacatg tgattcattt ggtagtcact atagtaatga
     1501 taagatagta aatacacttg atgaaaatga agaaaaggat tacttggatg ctttaagata
     1561 ctattatgat tgtataatgg gtccatttaa accatctatg gtaactgcta tagaaaagat
     1621 aaaagattta gatatagata ctgtatgtcc aggtcatggt ccagtattaa ctgaaaatcc
     1681 tagaaaaatt atagaccttt attacaactg gagtgtaaat gaacaaataa agttagaaaa
     1741 agaagttaca atttgttatg tttctgcaca tggatataca aagattatgg cagaagctat
     1801 aaaagcatat attgaaaaaa atagcaacta taaagtaaat ttatttgatg taatagagca
     1861 taagcaagaa gatattttgg caaaaatagc agtatcacaa ggtgtattat ttggaacacc
     1921 aacaatatta ggagatgcgt taaagcctat atgggatata ttaatatcgt taaacccagt
     1981 tcttcatggt ggaaaagttg cttcagtatt tggttcatat ggatggagtg gagaaggtat
     2041 agaaaatgct atggagagaa taagtcagct tagaatgaca gcagtaaaac cttttgctgt
     2101 taactttaaa ccatcaaatg aagagattga taaattacat tcttatacag gtaaattcct
     2161 agataagtta aattctactt ttggaagtaa aaagaaaact aagaaattta aatgtgtaat
     2221 ttgtaatgaa gtttttgaag gtgatagtgc tcctagtgta tgccctgtat gtggagctaa
     2281 ggaagaccaa tttatagaag ttgaagaaga tgaagttact tttagaaaag atactgatga
     2341 atatttcgta atagtaggaa atggagcagc tggtttttat gcagcagatg ctataagaaa
     2401 aagaaataaa acttgtaaga taactatgat ttctaatgaa gatgagttga cttactatag
     2461 acctgcactt tctgatggta taaatgaaga acttggttca gatttctaca tggaagataa
     2521 agattggtat gataaaaata atatagtagt aatattagga acgaatgtag ataaattaga
     2581 tgaagtgaat aaaactatta tagtgaatga tggagctatt aaatttgata agcttgtaat
     2641 agctacagga agtagaaact ttataccacc aattaagggt catgatttag aaaatgtgtt
     2701 tactcttaga aatataaaag atttatatag tgtaaaagaa gcactagaaa aatctaagaa
     2761 agttgtagtg attggtggcg gtttattggg acttgaagct gcatgggaat ttagactaaa
     2821 aggattagaa gtagtagtag ttgaagccat ggatagcata ctatcaaaac aacttgataa
     2881 agaaggtagt aaaatattag aacaatgtgt aagagataca ggaatagatg taagattggg
     2941 tgtagcagtt gatggtattg aaggtgatgg aaaagctcaa aaagttgtat ttaaagatgg
     3001 agatagtgtt gactgtgata tggtagtatt ttcaattggt gtaagagcaa acactcaaat
     3061 ggttcaggat acatctgtaa aaattgatag aggtattgtt gtagataaga cattacagac
     3121 aaatattaaa gatatatatg cttgtggaga tgttgcacaa gtgggaaata ttagtttagc
     3181 aatatggcca tcttcagtag aaatgggaaa aatagcaggg gcaaatgcaa gtggagataa
     3241 tttgacattt gaaagtgaag tatatccagt ttcattagat gcaatgaatg taaaagtatt
     3301 tagtattggt aatatacaaa attttgataa agaaatttca tcaaaagatg aaggtcaaag
     3361 aatatataaa aaattattta tgaaagatgg ttcattagtt ggagctatac ttataaatga
     3421 tttaagctgt actgttaaat tgataagatt aatatctgaa aaaggtgatt ttgaggatat
     3481 tatgaaggct gatatactat aatttaaata cattaaaata aaaaggagtt gtctcaaaat
     3541 tgattttttt ctaatcaaat tttaaattca actccttttt tgaattttta tataaaataa
     3601 catggaaatt ttagtaatgt ctgtggttac atacataggt ttaattattt tttatatgga
     3661 ttgtctctgg tataataaat tgaattgtgt ttgactgata gatattttta ttgaaagtta
     3721 atacctgtta tgcgataata aggacgtgtt aggggagttt ttataataac aattaatctc
     3781 agtttttgtg ttccaatggt agcatcaaca cattctgatg tagtagttct tttcttataa
     3841 aaattagtta caaatatgct tgtaattatt tgatatgtaa atttaccaat attataaatg
     3901 atgacctcga taataaggag agtgaaaaat aatctatgaa cgaaaatatt ttgattgtgg
     3961 atgatgaaaa agaaatagca gatttaattg aagtatattt aaaaaatgaa ggttttacag
     4021 tatacaagtt ttatacaggt aaggaagctc tagaatgtat tgaatctaaa aatttggata
     4081 tggctatttt agatattatg cttcctgata ttgatggatt tcatatttgc cagaaaattc
     4141 gagaaaaata ctattatcct atcattatgt taacagctaa aattgaagat atagacaaga
     4201 taatgggttt aaccataggt gctgatgatt atataacaaa gccatttaac cctttggaag
     4261 ttgttgcaag agtaaagaca caattaagaa gatatatgcg atataataat tcttatgaac
     4321 aacagtcgat aattgttaat gagtatgata ttaaaggatt gattatcaat aaagaaacac
     4381 ataaatgtag tttatttggg aaagaagtag cattaacacc gattgaattt tctattcttt
     4441 ggtatttatg tgaacatcaa ggaaaagtgg ttccttctga agaattgttt gaagctgtat
     4501 ggggagaaaa atatcttgat aataataaca cagttatggc tcatataggg cgattacgtg
     4561 aaaaaattca tgaaccttct aaaaacccga aatttataaa aactgtatgg ggagtaggtt
     4621 atacaattga aaagtaaaaa tattaaagtc aatcctgact ttactcaagt gagaaataaa
     4681 atttttatga gaacagcttt aatggcattt atagccatta ttttcatatg gattttatat
     4741 tcttttatat tgtatggtaa gttttctatc tggatagtat cattttttga aaatgctttt
     4801 cgtatggaat ataaagctgc attgaattta tatcagcaga ttttccgtaa tagcatggag
     4861 ctcttcatga tactagctat ggtgattgtg ttttttataa tattccgtgt ttatttaaat
     4921 tggtttacaa aatattttag tgaaataaat caaggtattg actctcttat caaagaagat
     4981 gttggagaag tggctttatc tccagagtta ttggcaatag aaaagaaaat aaactcaatt
     5041 aaacatatac ttgaacaacg taaatttgag acacaaatgg cagaacaacg taagaatgaa
     5101 cttattgttt atcttgcaca tgatttaaaa acaccactta catcagttat agggtatctg
     5161 acactacttc gagatgaaag tcagatttct gaagaactgc gaaaaaaata tttatctatt
     5221 tcgttggata aggcagagcg tcttgaagat ttaattaatg aattctttga aattacaagg
     5281 tttaatttat caaatatatc acttgaatac agtacagtaa gcttaactcg tatgcttgaa
     5341 caactaacat atgagtttaa acctactttg atgagtaaga atttaaaata tacactgaat
     5401 gttacaccaa atatgatgat aaggtgtgat gttaataaaa tgcaacgtgt atttgataac
     5461 ttattacgaa atgctgttta ttatagtttt gaagatacta ctattgaaat aacagctgta
     5521 caggaggatg attatataaa gcttaaattt atgaatcata gcaatacgat tccagaggaa
     5581 aaacttgagc gtatttttga acaattttac aggttggata catctcgtaa ttcaaacagt
     5641 ggtagagctg ggttgggact tgctatagct aaagaaatag tggagcttca taacgggaca
     5701 ataacagctc atagcgagaa caatataatt acctttaagg ttattattcc gattgtagga
     5761 aatttgtaag aatttaagta taaaaaaata ggaaattctt taggataaat aaataaagag
     5821 cactcttgtt attgatataa ttactgtatc aaaacaagag tgcttttatt ttgatacagt
     5881 aattatatca atagaaaaat gtgaaaatat attatgtgga acagatgcaa ttgtaagtga
     5941 aggttgattg gatttgaaat agaaaaagta ttttaacatg tttctgtaga ttgtataaaa
     6001 ataaataaat caacaaagga gaatcaaaga tgaataataa aaaaattgca gttatatttg
     6061 gtggaaactc aacagaatat gatgtatcat tacaatcagc ttttgcagta cttgagaatt
     6121 tgaatacgga aaaatatgat attataccaa ttggaattac aagggagggt aattggtatc
     6181 attatattgg agattataat aatatccaga ataacacttg gtttgaaagg gatactgata
     6241 taattccagt tattgtttcg cagaaccgtg tcaaaaatgg tattattgaa tttttaattc
     6301 ctgatgctgt ttctcagaat catattccaa atagtgctat tgaatcatgt gaaaatgata
     6361 ttaaatacac taaacttgat tttgtgtttc ctgtattgca tggaaaaaat ggagaagatg
     6421 gaacagtgca ggggttattt gaattggcag gtatacaggt tattggatgt ggtactcttt
     6481 cttcagcatt atgtatggac aaagacaaat cacataaact tgttcattca gaaggtatta
     6541 aagtaccaaa atcaatatta ctaaaatact cagataaatt taatgtggct gaactgtcaa
     6601 aagacttaac ttatccatta tttataaaac ctgtgcgtgc aggttcatca tttggtatta
     6661 gtaaaattta taaaaaagaa gagttacaag tagcagtaga cttggctttt gaacatgata
     6721 atgaagtaat aattgaggaa aatattgatg gttttgaggt agggtgtgca gttttaggaa
     6781 acaatgactt acttgttgga agagtagatg aaatagaatt gtcaaaagga ttttttgatt
     6841 atacagaaaa atatacattg aaaagttcaa aaattcatat gccagctaga attgatttgg
     6901 attgtgagaa aagaatacaa gagacagcaa aaattattta tagaactctt ggatgttctg
     6961 gatttgctag agtagatatg tttttaactc catctggtga aattattttt aatgaagtca
     7021 atacaattcc tggctttact tctcatagtc gttatccaaa tatgatgaaa ggtattggac
     7081 tgtcttttga agaaatattg gacaagataa ttgaggtgta cataaaatga tgaataatat
     7141 tttattagat aaaaataaag aagataaaat gacaaatact atcttattga ctaaagataa
     7201 agtttatgat gggaatctaa ttctagtaaa tgctttttta ccagttaaaa catctgaaga
     7261 tatagattta attcctgtag atacaaggtt tccaagtatt cttatgaaac gtgaagctac
     7321 aaacatttta caaaatattt taaaaagtat atgtggaata aatgaaatag tacctgtaag
     7381 tggatatcgt actgcagagg aacaacaaga tatatattca agttctctgc gtgacaatgg
     7441 aaaagacttt actaaaaagt ttgtagcact tccaaatcac agtgaacatc agacagggct
     7501 tgctattgat ttagggttaa agaaagaagt tatagatttt atctgccctg aatttcctta
     7561 taatggtatt tgtaatgagt ttcgtaaggc agcactacat tatggtttta tagagcgtta
     7621 tcagtgtaaa aaagaagaaa taacaggaat atctcaagaa ccatggcatt ttcgttatgt
     7681 gggatatccg cattctgaga ttatcaataa aatgaatctc gctcttgaag aatatataga
     7741 atatattaag agattttcgt atacaaattg tttaaaaata gaagataaag aaaaaattat
     7801 agaaatcttt tatgtgccta ttcatactaa agaagaagtg agaatctcta tacctgaaca
     7861 atgtgtatat caaatatcgg gtaacaataa ggatggtttt attgtgacat tttggagaaa
     7921 tagaaaggac taagaaatgg aggaacaaga atgattagga ataaatctta tgcagggctt
     7981 gattatttta ggattatagc tgcattactt ataattgcaa ttcatacatc tccattatta
     8041 tcatatagta aaatggctga ctttgtgtta actagtataa ttgctcgtat tgctgtgcca
     8101 ttctttttta tgctatcagg cttttttcta atttcaacat ataattataa ttgtaataaa
     8161 ctgaaatctt ttctaaaaaa tgtattattt atttacggga tagctattgt aatttatatt
     8221 cccttaaata tttacactgg atatttttcc atgaataatt tagtgcccaa tattattaag
     8281 gacattgtat ttgatgggac tttatatcat ttatggtatc ttcctgcatc aattattggt
     8341 gcaagtattg catactttct tgtaaaaaaa ctaggtttaa agtactcact agtaatcact
     8401 attgttattt atgtaattgg tatgtttggt gatagttatt atggtttttt agaaaaaata
     8461 ccactattaa agaatttata tgggtatatt tttgaagtat cagattatac acgaaatggc
     8521 atattttttg cacctgtatt tttcatactt ggtggaataa tatctaataa atctaattat
     8581 atgtcaacta aaaatagctt gattggattt cttatatcat tcttacttat gttatgtgag
     8641 ggaatgtttt tacataaact aggggtacag cgtcatgata gcatgtatat tatgttattg
     8701 ccatgtatgt atttcttatt tacagcctta acatttttga aaggttctcg agctaggtta
     8761 ttgcgaacat catcattaat tatttatatt atacatccta tgatgattgt tgttattcgt
     8821 atgttttcta aaatattcgg aatacaaact gtcttggttg acaatagcct tattcattat
     8881 atagtggtaa gtatagcatc ttttatagct tctataatta ttatattgat tcttaaacct
     8941 ctaaaaaaag acttgaaagg agaacataag gtaaatacca atagagcttg gattgaaatt
     9001 gatttaaata atttggaaca taatgtaaag atgatacaaa aagctatgcc agaagattgt
     9061 gaattgatgg cagttgtaaa agctaatgcc tatggtcata gtgcttttga agtagcgact
     9121 tgtgcaaacc aaataggtgt aaaagcattt gcagtagcaa caatagatga ggggattgat
     9181 ttacgtcgat atggaatact aggagaaata ttgattcttg gatatactaa cccaataagg
     9241 gcaaaggaac ttcataaata caatcttaca cagagtgtta ttgaccttaa tcatgctatc
     9301 tctttaaaca aacagaaata caacataaaa tcacacatta aaattgatac aggtatgcac
     9361 agactgggtt ttgatgttaa tgatgtgagg tcaattttaa aggcatttaa attaaaatac
     9421 ttagatatat gtggcatatt tacacacttg tgtgtttcag atagtctgaa agatgaagat
     9481 gtagacttta caaataaaca aattgaatgt ttttataagt taattgattt tctgttaaaa
     9541 aaaggtgtaa aaattcctaa agtacatatt caaagtagtt atggtttttt taattatccc
     9601 aatcttaagt gtaattatgt aagaattgga attgcattat acgggatatt aagttctcca
     9661 aatgatacga ctaaattgca acttgattta cgacctgttt tatccttaaa atcacaagta
     9721 attcttatta gaaaaataca aaaagatgat agttttggat atggaagagt ctttattgca
     9781 agcagagata gcgtaattgc tatattatct attggctatg ccgatggtat acctagaaat
     9841 ttatcctgtg gaaaaagtta cgtaataata aatggttgta gagcagcaat agtgggtcga
     9901 atttgcatgg accaacttgc tgttgatatt acagatatac ctaatgtaga agttggtaat
     9961 acggcaataa taataggaag agataattta tctgaattat ctgcttctga agttgcaaat
    10021 aactcgtgta gtatatcaaa tgaattattg agcagagtag gaaggaggtt aaatgttata
    10081 aagaagtaac tcaattaaat agtaatattt gttgtactgt gtaatttatt ttaatctgac
    10141 tagacatttt tagtaatatt atgtctaata tatatttttt ataacttaca tgacaattta
    10201 agctataaaa aggtgatgtt tcagattttt attttgaaac atcacctttt ttgttataat
    10261 atataataaa ataattatac cttaactgta aacttatata gattatttac tttttaatat
    10321 tagattcatt ttttgagatt ggtatataat aaacatatag agtatataat aatagttaaa
    10381 gttaaaaaag gggaaaagca atatgcagta tatacaagaa ttacttgatt tgactcaaaa
    10441 ttattgggtg ttagccacaa taatcggctt attaagtgca tttatagaaa gctttatacc
    10501 agccttacca cttgttgcta tagttacagc aaatgctgca atacaaggat tatttattgg
    10561 atgtttgtta tcatggattg gctcaggact tgggacaact tcattattct tattaataag
    10621 cagatttaat gatagtaagc tttttaataa gttgagaaat agtaaaactg aaaaagcaat
    10681 aagttggatg gataaacagg gatttaagtt attatttata gcgtatgcct gtccatttat
    10741 gcccggttgt ttagttacta tcgcatcagc ttttggtaaa aaagatttaa aagattttgt
    10801 gccagcaatg ttggcaggaa aatttgtaat gtttatagtt ataagttacg tggcaagtga
    10861 tatagaaggt tttataacaa gtcctttaaa gatagcatca tttatattat tggtgttttt
    10921 gtcatggaag attggaaata gagtaaataa aaatcttgaa aatcataatt atgatttcca
    10981 tcataaaaaa catcacaatg ataaagatga taaaatgatt tagcttgtac gaaataaaac
    11041 gtatcttaaa atgatttagt actaaattat tttaagatac gttttatttt ttgtattaag
    11101 gtacaaaatt tttagttctt ttgtaaacta aaatatataa aacttattta tacttagttc
    11161 aaaatattgt tatttatttt ttctacaact ataataaaat ataaaattga tatccaatca
    11221 aaaaaataac tatgaaattt aatagcttag atatgaattt ttctgttttt gagttagttt
    11281 ttataggtag taaagaaatg tttatggtaa tgggataaaa caattcaata ccttctttag
    11341 taataaggtc aagacacaag tgagatagat atcctattat aaacccactg gacaaacatg
    11401 agaaaactat attattgtta gtgaagattg tcagagattt aaaaaaacta taaataagta
    11461 ataaggcaat tagactgtga gtaaaccctc tatgtctaaa cctacttcca aataatttgt
    11521 atattaacat aaatttttta cttatgtaag aacctctcat atctatatct ggaaataaag
    11581 aacctaaata tgcaaaataa atataaatta taattaatac tattttatat gcaatatcgt
    11641 atttaactag gtatagattg tttataaagg ggagtatcaa aagtgcgaat atataacctc
    11701 ccctttcatg tgtttctttt atcatataaa aatcctcctg aatcgtcact ataaacatta
    11761 tattggtaaa tttagactat cttttattat attatatagc aaacataagt ttttttcaaa
    11821 aggattttaa tatttaatta atcttgagat tttaaatttt tgtaattttc taaagcacca
    11881 ttccaattta ctacattaaa ccagttgtca atgtattcat ttcttctatt ttgatatttt
    11941 aaatagtaag catgctccca aacatcaagt cctattatag gagttaggtt tttacttaca
    12001 gggctatcct gatttggagt agtcataata gataatttcc catctttagt agctacaagc
    12061 caagcccaac cagaaccaaa gacatctaaa gcagattttt ggaactcttg cttaaatttt
    12121 tcaaaagaac caaagtctct atcaatagct tcttttaaag attcagaagg tatggttttt
    12181 tctggtgtca ttatatcaaa aaagaattta tgattataag ctccacctgc attatttctt
    12241 acagttgtag caatatcttt aggtaaagaa tctaaatttt gcaataattc acataaagaa
    12301 taattataaa gctcaggata tttttcaaga gcagcattta atttatcaac ataagcttga
    12361 taatgcttat catgatgcag tttcattgtt tctttatcta tataaggttc aagtgcatca
    12421 tatgcataag gtaatggttt aaccttaaat ttgttatttt caggtgtaaa agcaaatgaa
    12481 gttatgcact gtgagattat aaataaagac ataataactg gtattaatat ttttttcttc
    12541 ataaaaatca cctcctaata tagtatttct agaaataaaa aaaatatgaa atattaacag
    12601 ataatttata agaatttaat agcaatttca ttttaaattg aataagtttt aaagccaaag
    12661 acaaaactat gaaatataga ataagactaa aggacagaaa ggaattttga ttatatggac
    12721 ggcaatattt caatttatta taaaggtgat atatctaaaa aagaagatat taaatttaaa
    12781 ataaaagaat ctgtaaataa tacaagactt tctagtagaa tagagtataa ggatgaggaa
    12841 aaaacttttg attttgaaag atttaatgta attgatgcta tttatggaaa taaaccattt
    12901 gaaaaagatg gaaaagttat tgtttttaat ggaaatatat ataactatca tgaaataaaa
    12961 gaagaattaa ttaaaaaagg acacaatttt actacaaatg atgatattga agtcttattg
    13021 gcatcttata tagaatttgg taagaattgt gtacataaga ttaaaggaat gttcaacttt
    13081 ataatctatg atagagaaaa tgaaagtata tttggagcaa gagatttatt tgggataaaa
    13141 ccactctatt atataaataa ggaaaatgca ataatttttt cctcagagta taagttttta
    13201 cttgaatata tgaaaaattt aaatataaat gaaagaagct tacaaagtta tttttcattt
    13261 caatatgtac ttcctgaaga tactatgata caaggaataa ggctgatacc agcaggtcac
    13321 tattttaggg tagaaaatgg tatactatct ttaaagagat ataataaact tgagtttaga
    13381 agtagtacaa aattttttta tactaaaaat cacttaggca atagagatgt gaacgaggat
    13441 gatataagaa atatagtagt agattcaata gtaactcata tggaagagga gaaagaaatt
    13501 ggaacatttt tgtctggtgg aatagattca tctattataa ctactgtggc ttcacaaatt
    13561 aatccaaata taaaatcttt ttctgcaggc tttagtgtca aaggatatag tgaattagaa
    13621 gtagcaaaga aaacagctga taagttaggt atagaaaata tccagattaa tataacacaa
    13681 gatgaatata taaaatcatt accgaatgta atttattctt tggatgaccc tatagcagac
    13741 ccttcagaag taggtcttta tttcttaatt aaagaggcag gtaaacatgt taaagtagca
    13801 ttgtctggag aaggagcaga tgaattattt ggaggatata atatatataa agagtatagt
    13861 actatgaaat cagttgtcaa ttcacctact tatattaaaa gtatattagg aagagtttca
    13921 gaacttatgc caaacataaa aggaagaaat tatctttata gagctacaac accattagaa
    13981 aaaagatata taggaaatgc aaaagttttt gaaaacagcg aagtaaaaag attctttttt
    14041 aagtataagg aaaagaatat atatgaatac ctgttgtcta atttgtatag agatgcacaa
    14101 aaaaataatt acgattatat aagtaaaatg caacatatag atgtgaatac atggcttcaa
    14161 ggcgatatac ttcaaaaaat tagcaaactt tctacagctg agcaggttga acttagagta
    14221 ccatttttat ataaagatgt atttgatgta gcaaaaaatt taagaatgga gcaaaaaata
    14281 aataagaata atacaaaagt tttacttaga gaggcgttta gagaaatagt cccagaacat
    14341 gttgttcaaa ggaaaaaatt aggatttcca actccaataa gagtttggtt aaaagattct
    14401 ctaggggata ttgtaaagga aactatttat aattcaaatg tagatgaatt tatagataaa
    14461 aaatatgcaa taaaactttt agatacgcat cttaaaggtc atagagataa ttcgagaaaa
    14521 atatggacta tatttacatt ttgtctatgg catcaattat ttattgagca taaaaatgtc
    14581 gagtattaat acttttttca atattaatca gagggcaaaa gcatgcaatg ttttcaccct
    14641 cctgattatt atggaatagg ataagtagaa ctttgattga ttagtttact atctcaataa
    14701 aattattggc aaatattttg acaagattac tttcaacagc taaatttaag ttttgtccat
    14761 catcatatcc agcggaaatc aatcctagta agtttccaaa catatctaaa agagctcctc
    14821 ctgaactacc actagagatt ggagctgtaa attgtatcat ttgaaccgtt tcaaaatcac
    14881 gaaaagctga aataattcca tctgaaactg tattaaaaag acctaaaggg cttccaattg
    14941 caactatttt ttgacctctc acaggttttt tactgacttt aacaggtatt ggcttgcatt
    15001 ttctattaac ctttatcaca gctaaatcat aatctgaatg gtattttata atttggtaag
    15061 atgtataaac tttatcatca ttttcaaatc taactaaaaa tgaataccca tcattgacta
    15121 catgaagatt cgtaagtata taaccttcat tatttattac tactccagaa ccgctcttaa
    15181 acggtttatt ttcgttattg cacacaacaa tcataacaac agaagctgat aactttgcaa
    15241 ggtcttcata agaaagttct acttcctcat cttgtacaat ttttttagat gttagatttg
    15301 tgttattaag tgtattttta gagttaggtt tattcgtagt aggagaagtc ttattggtat
    15361 tttcactgta atttatattt gtaatatgcc tttcaaaagg tatttctaat atatttggag
    15421 tcttcctaga aagttcaaat agagtagaaa attttgaaca ttcaggatat aaatcaagaa
    15481 tatctttatt tggatttata tataaaatat cacacccaag ttgtgataaa aaatataaga
    15541 aaaaaagttc ttgcctttta atatttccaa agtatactat ctttggtgaa atagtagtct
    15601 tcaccttgtt ataaaataat ttaggtagaa aatagtccat ccaacacaaa agtttaactg
    15661 caaagttttt gatgatagag gatgtacaat ttggcatact tgtggaaaat aaatctaaag
    15721 tatttttaaa tacaatcttt ttagtccaat ttaaggtgtc attttctatt ttacatggaa
    15781 agtcgatatt atataaatcc caactgttaa acttagaact atcataaata ttaaaaattt
    15841 taagcatctt atctgtttgt tctttgtcaa aatttatttt tagattgttt aatctaatat
    15901 agggaattgt aggattatta aaaaaataag tatctatatt tttaattttt tctatgtatt
    15961 tatcaattga atcatcaaca cctatatatc ttgtaaagta gacttcttta atatatgaag
    16021 aacccttatt tttataggta gtatcagata taaattcaat tagaggttca gtagactttt
    16081 ttattgaaat ctttaatggt ttaatagtac aaatcatatt ttttctccta taataagatg
    16141 atataatcta ttataaaaca acttaaaaca atatagtaca ataattttgt agtttcaaaa
    16201 taaaatatgt acttgtttat ataaatgata tataattaca tattaaacat agcttttata
    16261 catttaataa agtatgtaaa atctatgtaa aaagtaagaa atataaacat ttttttaatt
    16321 atattttaaa aatatcaagc aagttttctt cacaaatgaa taaaaaatgt tataatatga
    16381 ttaaagaaaa agataaataa ttagcaagat ttgtttagct aaaattaaca agggagcgat
    16441 aaattatggg tataacatta tcaaaaggcc aaaaggttga tttaactaaa ggaaatccag
    16501 gtcttaaaaa tattttagta ggtttaggat gggatactaa caagtatgat ggtggatttg
    16561 actttgattt agatacagca gcatttttaa caggagcaag tggaagtgtt actaatgatg
    16621 gagattttgt attttacaac aatttaaaac atacatctgg agcagttgag catctaggag
    16681 ataacagaac tggcgaaggt gatggagatg atgaacaaat agttgttgat ttatctaaga
    16741 ttcctggaga aataagcaag atttctttta ctgttacaat tcatgatgca acagaaagaa
    16801 gacaaaattt tggacaagta agtaattctt atataagaat agtagataaa gacacaaatg
    16861 aagagttaat aaagtatgaa ttaggagaag attttagtat agaaacagct atagtagtag
    16921 ctgaaatata taagcacaat ggagaatgga agtttaatgc actaggttct ggctttgaag
    16981 gtggtcttgc tgcattatgt ggaaactttg gaataaactt ataatttcaa ctataacaat
    17041 aaactaaagg gggatatttt ccatggctat agtattaaaa aaaggacaaa aaatcgattt
    17101 aactaaggga aatccaggtc ttaaaaatat aaaacttgga ctaggatggg atacaaattc
    17161 atttgatagt ggctatgatt atgatttaga tgtaagtgtt ttcatggttg gagaatctca
    17221 aagagttgaa aaagatgaag attttatatt ctacaataac ttaaaacatc catctggagc
    17281 agttgaacac ttaggtgata atagaactgg tgaaggtgat ggagatgatg aggaaatatt
    17341 agtgaattta gagacaatgc caaagcatat acaaaagata gctgtaacag ttacaatata
    17401 tgaggctgct gaaagaagac aaaattttgg acaagtaagc aactcatata taagagtatt
    17461 aaattctgaa aatgatgaag aaatattaag atatgactta ggtgaagaat ttagtataga
    17521 aactgcaatt acagtatgtg agatatataa gtataatgga gaatggaagt ttagtgcagt
    17581 tggagcagga tttgaaggtg gcttagaagc actttgtaga aactatggct taaatgttta
    17641 atttaagcaa tataatatat taaatataaa taacctatac aaataatgta taggttatat
    17701 tatataaaat tttgtggagg tttagtatgt cgattaattt atcaaaaggt gataaaatag
    17761 atttaaaaaa atctaaccca ggactgagta acatacttgt aggtctagga tgggaccctg
    17821 tgcaacaatc tggaggaggt ttttttaaat cgttatttgg tggaggacaa gctgatatag
    17881 attgtgatgc atctgtattt atgcttaatc aagaaggtaa attaagtgga ataaaagatt
    17941 taatttattt tggaaatcta aaaagtgcct gtaaatcagt tttgcataca ggagacaatc
    18001 taactggtga gggtacaggt gatgatgaac aaatcctagt taatttggat aaagttccat
    18061 caaatattca taaattattg tttgtagtaa atatatacaa ttgtgtagat agaaaacaac
    18121 actttggaat gatagaaaat gcctatataa gagttgaaga ccaaggtaat aagaaagaga
    18181 tagcaaaata caatctatct gataattatt ctgaaaaaac tactcttata gtaggagcta
    18241 tatatagaaa agatggaagt tggcaattta aagcaattgg tgaaggaaca aaagatgcgg
    18301 gtcttaaaga agtaatgcaa aatttagaca ggattgagtg tgcatatgga atttaataat
    18361 gatatcaaat attataatgt agataaagaa gaagttacaa aagacttatc tgttaatcct
    18421 gaaaaaggtt tatcagaatc agaagtcaag actagaagag aaaaatatgg tttgaatgaa
    18481 tttactccaa aagaagaggg tagtttttgg gatgatttaa aggaaagttt aagtgaacca
    18541 atgatagtta tcttgattat tgcagcagta gtaagtgcag taattgggga aactcatgat
    18601 gcaataggga ttgtaggtgc tatagcaata ggtatagcaa taggtatgat tacagaaggt
    18661 cgttctaaga aagcagcaga ggctctttct aagttgactg aaaacataga agtaaaagta
    18721 ttgagagatg gggaagtaca tcaaatttct aagagtgaat tggtaccagg tgatatagta
    18781 tatattgaaa ctggtgacat ggtacctgct gatggtagac ttatagaaag tataaacctt
    18841 aaaattagag aagatatgtt aacaggagaa tctgatgacg tatctaaaaa gtgtgatgta
    18901 gtagtttcta tggaagagat agaatctaaa ggagcagtag tagtacagga gccaatacct
    18961 gcaaaacaga taaatatggt gtttggtggt acacttgtag cttatggtag aggagctcta
    19021 gttgtaactt caattggaga taatagtgaa atgggtaaaa ttgctcaaaa cttatcagaa
    19081 acagatgagc aaactccact tcagataaaa cttggaaatt taggtggttt gatagccaaa
    19141 gtttctagtg cagtagcagg attactattt atatttatgg ttttccaaat gataagtaag
    19201 aatgtattaa atgtagatat gtctggaata ttaccgtttt tagaatcaat agacccagtt
    19261 aaaacagcat ttacagtatg tgttgcgttg atagttgcag cagtgccaga aggtcttcca
    19321 actatgataa atatgacact tgcaataaca atgcaaaaaa tggctaaaat aaatgcatta
    19381 gttaccaaaa aagaagcttg tgaaacgata ggttctgttt ctgtaatatg ttcagataaa
    19441 actggtacat taactgaaaa tagaatgact gtagaagttg catatgttga tggcagatat
    19501 attgaaagtt cagaagagga aataaatagt tattttgaag aaaactgtat gataaactct
    19561 acagctgatg tagagcacaa tgatggtgat attaagtatt taggaagtgc tactgaatgt
    19621 gcattgcttt tatattacaa aaacgtagat tatagacaag ttagaaaaaa ttctaatata
    19681 gtagctcaaa atccttttac ttcagattca aagagaatga cttctgttat aggtcgagat
    19741 aatcatcatg tgctattatc aaaaggagca ccagaagtat tacttgaatt atgttcacat
    19801 attcaaagag gaaaagacat agttccatta actgaaaata taaaacatga gattttagaa
    19861 gaaataaaga aattgcaaat aaaatcaatg agaactttag ggtttgcata taaagaaatc
    19921 tcacaagctg aagaagaagc agcagtaact gctgaaagtg atgctatgaa tgtaagtgca
    19981 atggaaaaca atttagtatt tagtggtttt gttggtataa gagacccact tagaaaagat
    20041 gttatagagt ctgtaaatac agcaaataaa gctggtgttt ctgtaaaaat gcttacagga
    20101 gataatataa atacagcaag agctataggt gaagagttag gcctattaaa aaataatatg
    20161 agagtggttg aagcttcata tatagatact ttagatgatg aagaattaaa acaagagata
    20221 caaagtattt caatcgtggc aagaagtaaa ccagatagta aaatgagaat agtttcagct
    20281 ctgcaaaaga gcggagatgt tgttgcagta acaggtgatg gtataaatga tgctccagca
    20341 ctttcaaaag cagatgttgg tatagcaatg ggtatatctg gtacagaggt atctaaaaac
    20401 gcagcagaca taattttaac tgatgatagt tttagtacca ttgtaaaagg tattaaatgg
    20461 ggtagaggaa tttatgataa cttccaaaga ttcgttcaat tccaattaac tgtaaatgta
    20521 attgcatttt tagtggctat aatatctcaa gttatgggac aagagatgcc atttactaca
    20581 atacaattat tatgggtaaa catcattatg gatggaccac cagcactagc attaggttta
    20641 gagccagtta gggaccatgt gttaaacaga aaacctgttg atagaaaagc caatataatt
    20701 tctaagtcaa tggtgtatac aatagtatta aatgcatttt atataacagc aatactaatg
    20761 ttacaatcta catttaattt cttaggagtt gatgaagcgc ataagggaac agtaatgttt
    20821 gcgttatttg cttttagtgc actgtttaat gcatttaact gtagagagtt taatgcagat
    20881 agtatcttcc ctaattttac acataacaaa ttagcactac aaataatagt gttgacagga
    20941 attgcacaag taatatttac tcagctattc caagatttct ttaactctgt agcaatggat
    21001 tttatgacat gggtaaaagt tttatgtgta gcagcaagtg taattgtggt taatgaagtt
    21061 gtaaaatgta taataagact ggtaaaacca aaaaagactg cttaaaacaa attttttaga
    21121 agaaaacaga ctgactcaaa atatgaattt tgggtcagtt ctgaataaac atttaaattg
    21181 ggaggatagt tatgggtgac tcaaaggtat ttgaaaaaat attctccagc caatcagata
    21241 gaggaaatta cactccttca aagggatatc taagttattt tatttcgtat attggtttag
    21301 aagatgaagt tttgtacaat ctcgagatat ttaaaacaaa acaaaatatt gatagcaaaa
    21361 aagatattgc tttatttact gatgttatag caaatcctag tgattttgat attataaatt
    21421 attttaaaag tggacttcaa aaatatagaa ctagcatgga agatgtagat ataaatattt
    21481 tgggatttga agagattgat tataaaataa agcaagcaat ggatagagtg ttaaaagaag
    21541 aggaaaaaga atttactaat gatagagtta aacaaaattt tatagtgaaa ataatggcat
    21601 ggataaaaat ttatatcggt gctttagata taaataaaaa tgaagctcca aaagtaatat
    21661 tttatggaga tataaaaaaa catgaagttt atttactctt aatattatac ttggcaggtt
    21721 ttgatgtttt atatcttaat ccaaattcaa agagtaatat agatatttta aaatcagaaa
    21781 gatacaatat agagtttgaa gaagccaaca taatagaaga aaaaatttct tttgaagaaa
    21841 gggttatttt aggggaaaaa atagataaaa gttctgtaaa aaaagctttt actgttgggg
    21901 cagaagcatc aaagcgtata agtgaggaat tgttaaatga tgcaggattt ataaaacctt
    21961 ggcaactcca agatagaaaa ataaaaaatc tacttctaag ttcaactgtt gatgaaatat
    22021 caatatactg gaatcaacca cttaaattaa gaccaggatt taagtttaat gatgctattg
    22081 tagaagctcc aaattttctt tctaagatta atggaatata taacgataag aatgaatata
    22141 ttaagttttt agatttatta agagattcgg aaagttcaac atttattgaa tttaatggag
    22201 atgtagatag attttcaaaa gcttttacaa gagaagcttt tagtttatcc tttttattgg
    22261 attcaaaagg tgcaatagat aaaaactctg ttttaaataa taaagattat tccatatcaa
    22321 cactagcatt gaatcaacaa attatgattt tagagaaagt ggaagagttg ttagaaggaa
    22381 gtatgttttt gaatggttta agtggagaag acaagataaa aggtctattt acagtacttc
    22441 acatggataa gaaatttgtt catatgatga acaatttcga ttactcactt ataaacccaa
    22501 aattgattat atacatgtac aagagtattg tatttgataa agaaatagtt tttcttatgc
    22561 ttttacttag taagattgga tttgatatta tcatattatg tccaggagga gaaaacaata
    22621 tagagaatgt tataaataac caattgattg atgtacacag attggataaa atggtatatg
    22681 accttaaatt aaattcgctt gaaaatgata tacctttact taaaaaaatt tttggaaaga
    22741 ggagacgatt ttagatgggg ataaatataa atagtttttc aaaagataag aactctgtag
    22801 aggttactga gaatttgcct acagcagttc aagaagaaaa cttcgatata atggaatata
    22861 caaataataa aaaaaatgaa ctgagaaagt ctaaggaagt tgaggcattg acatctctta
    22921 tagaagtaga aaatccagat acgattttac agtttggtag gaaagcatct gaaggagtag
    22981 caagagtttc tgatagcctt ttaaatacaa taaaattaaa tagaaatgaa gaaaattcta
    23041 aaatgctggt tcatttaact aaaataatgg ataagtttga tttagacgat tttcaagaaa
    23101 ctaaggaacc aaatttcgtt caaaaacttt tcaaaaaagc taataatgcc attgaaatga
    23161 tgtttcaaaa gtatgaaaca ttgggaggag aagttgagaa aattcaaatt gagcttgagc
    23221 aatacgaaag agatatagca ctttctaata agcaaatagg tgctatgtta aatgaaaact
    23281 ttgagtttta taatgaactt caaaaatata ttgttgctgg agaaatggca atagaagaaa
    23341 tggataatga aatactacct ttctttaaac aaaaatcaga gactagtgga gatcaaatgg
    23401 atgttgtcaa ttatcaagaa ctattaaaag tttatgatat gttaaatcaa agagtctatg
    23461 atttaaggat agcagaaaat atagctatcc aaacaatacc tatgcttaga ggtatgcaac
    23521 ataataatta tggtttaatt agaaaaataa atagtgcatt tgtcgtaact ttaccagtat
    23581 ttaaacaatg tttatctcaa gctatattac ttaaaaagca agaattacaa gcaaaatctc
    23641 taaaagcact tgatgacaaa actaatgaat tattgcttag aaatgcacaa aatgtaagta
    23701 ctcaaagtgc acaaatagct agaatggctg gaacaagttc tgttcaaata gaaacattgg
    23761 aaaaaatgta caatactatc aaatctggta tagatgaaac tatgagaata gaagaaaaca
    23821 atagagcttt aattaaggat aatacaaaga gattggaaga attaaatacg actataattt
    23881 ataataagta gtattatatt aagggctaat ttgtataaag ttggcccttt ctatgtatat
    23941 gaggaggcta gacattgaaa tatttcgatt atatctgcaa agatgattta gagagaattt
    24001 ttttgaagga gccagaagat tttagtgcta agactgaaaa agatgtgttg aaatatgcac
    24061 tgggcgcttt tttatacgtt ccagctactc aatataatat gatttataag agtattatag
    24121 gggatgttaa gggagttaga ccattagcta tttgtttaga agatgctgtt ggagtaaatg
    24181 gagagttaga ggctatagag aatcttagat taattttaaa aaatattagc aatgaaagta
    24241 taactaataa agatggaata ccactaattt ttgtaagaat aaaagatgtg gagcaactgt
    24301 tgagaattaa agagattata attaaaaata gtcattttat aacaggaata ttaattccta
    24361 aagcaaattc ggagttaatt gaaaattgta tagaagcttt agattctatg aatcttcaag
    24421 atatgtatgt tattccgata gtagagacaa aagaatttat atataatgaa aaaaaagaac
    24481 ttagttttac taatttgtac aatgctattt taagacataa gtcaagaata ttaagcatta
    24541 gagtaggcat aactgatata ttagggatgt atggtataag gagagataaa aacttctcta
    24601 tatataataa tttgatttgt tcttcattta tattagatat aatcacatat cttcaaagac
    24661 cagagttaga tatacctata agtggtggag tatcagaatt ttttgatatg acgaataagg
    24721 atataagaaa taagtatata gaagaaatat tattggataa atatcatgga ttaattggaa
    24781 agaccgtaat tcatccaatg caaattcaaa ttgtacaagc gctatctaca gtatcatatg
    24841 aagattttgc tgatgctttg gatatactgg atagtacaga cagtaagtat ggtgtgagca
    24901 agggtgtatt aggagagaga atgaatgaaa caaatccaca ttttttatgg gctaaaaaaa
    24961 cattgattct atctaaaata tatggtgtat taaataaagg agtagactat gaagaattgc
    25021 ttaaatttta attgtgagat tgacattatt gataatccat tgaatttaga actaaatgat
    25081 tttttagacg taggaataag aaataatagc aaaagacgtt ttttgtttat ctcaaagaaa
    25141 ctcggtaaac atttagcatg taagccaagt gagatggata atttgggaaa attaatggct
    25201 acaatttata atgaaaaaaa taaggaagaa tcaaatggta ctgttatagc ttttgctgaa
    25261 actggtacag ctgttgggca tagttttttt gattacttat gtggagatta tgaatttatt
    25321 catactacta gagagcagtt tgacgagtta gaaaatctgg aatttttaga ggaacattcc
    25381 catgcaacag accagaattt atactttggt atgcttaaca actttaaatt tggagatgag
    25441 ataatattgg ttgatgatga gattaccaca gccaatacat gcatgaatat aattaggaaa
    25501 attcaaagca tttatcctaa aaagaaatac actatatgct caatactcaa ttgggtaagt
    25561 gatgaaaatt taagtaaagt tactcgttta gaaagagagc tagattgtaa gatagatttt
    25621 gtatacttat ttaaaggaaa ctttaaattt tatatagatg aagatattat ttcaaattac
    25681 aacgataatt atagtattac taaattagag actatttcaa gtgataaagt aaatttagta
    25741 gtaaatcata tttatgttga tttagaagat tatattggaa ataagaaata tgtaaaatat
    25801 acaggaagat ttggaattaa tagaagagaa caatttagat taaaagaaat cgttaagaga
    25861 gaaagtaaaa aaataactat ggccagtaaa gaatctttaa aaaatgaaaa agaaaagatt
    25921 ctatttttag gtactgaaga atttatgtat atacctatgc tgtttgcaaa agaaaaagaa
    25981 aataaatatg atatatacta tcattcaaca acaagaagtc caattattaa tattgataag
    26041 aataattatc ctattaaaag taaatttatg ctaaagagtt tttataatat agatattcaa
    26101 aattatattt acaatataga taaacataat ttttctaagt gttatttatt tgtagagctg
    26161 aataaaagtg aaaattctta tctagaattt attgatataa ttaaaaaaac aagtataaaa
    26221 gaattaacta tagtatgttg tagctaaagt gttttaacag gataaaatat atcacgattt
    26281 taagatagga gttgagtcat atgagagatt ttagcacgta ttctaaagat gatgttattt
    26341 ttttattaaa agatatatca aatttaattg aagaagaagg aaataaagaa agagaattaa
    26401 aaatacaaaa tggtagacat tattcagaaa tgataccaat agagtatgaa gttagtgaag
    26461 attatctgaa tttatatcat gagaaactaa gagaaaataa agataaactt gcattttcta
    26521 taggagttat gtgtgaaaaa ataattaaaa aaaatggaaa tgatgtagta ctagtttcac
    26581 ttgctagagc aggaacacct attggtattt tggcaaaaag atatataaga agcaagtata
    26641 atataagttt acctcactat acaatctcta taataagaga taagggaata gatatgaatg
    26701 caattgaata tatagtaaag aatcatccga gctcaaaaat tcaattttta gatggatgga
    26761 ctggtaaggg aactatatca aaagaacttg aaaaagcatg tgatgaactt aatgttaaat
    26821 ttaaaaaata ttttgactca acacttgctg tattagctga ccctgctgga tattcaggac
    26881 tttatggaat tagagaagat ttcttaatac caagtgcatg tttaaattca accgtttctg
    26941 gtttagtaag tagaactgta ctaagagagg atttaattgg taaaaatgac tttcatggag
    27001 ctaagtttta tagacattta aaagataaag atgaatctat gaactatatc aaaactatag
    27061 aagaatgttt taaaaatcaa tttaagaata tatctgatga agttgaaaac tgggaaagtg
    27121 acattataac aagagatgga tactttgatg ttttaaatat aaaagaaaag tataacataa
    27181 cagatattaa ctttatcaaa ccaggtgtag gggaaacgac aagggtttta cttagaagag
    27241 ttccgtataa gattcttgtt aaagacttaa atgataaatc tttagaccat atattcatat
    27301 tagctaagga gaaaaatgtt gaagttgaac aaatggattt aaaagcctat aaatgttgtg
    27361 gaataataaa aaatatgaaa gatatttagg aaatatatta gacaggagaa tattgaatga
    27421 ttgttttttc agatttagac aggagtatca tttactccaa taaattttta aatgctgata
    27481 gtaaatatac taatatagaa atttataggg aaaaagaaat atcttatata tctttagata
    27541 ctataaattt aataaagcaa atacaatatt atggtatgtt tatacctaca actactagaa
    27601 cagtggagca atttaagcgt atagaattta ataaatatgg gatttatttt ccttggagta
    27661 taacttcaaa tggaggagtt atacttaaag ataatgaaat attgaaatca tggagtgaaa
    27721 aaatagataa actaaaatct gattatgagc ccattgaaag tatgattcat aaatttaaag
    27781 actatttgaa tgtagatgga ataactaatt ttaaagttgc agaagataca tttttttata
    27841 tagttgttga tttatcaaga tttaatttgg attcaatcaa agaatataca aatatattgg
    27901 aatcaaaaaa ttggaagttt tatgtgagtg gcagaaaaat atattttata ccaaaagaaa
    27961 tttcaaaaga aaatgctata aaatacttga ctaaagaatt aggaatagaa tatttttatg
    28021 cagttggaga ttctattatg gactatggta tgcttaatat ctcaaataaa tcctatgtat
    28081 tgaagcatgg tgatataaat aaaaatgaaa tagaaaattc atttatatca agttctttca
    28141 atggaatgag tggaactgaa gagatactat ctaacatttt agacgagaac tgcctactta
    28201 acatataatg actgatatat aaataataaa ctagaaaaat ctgaaataaa ttatagtaaa
    28261 gtttatcata ctaatttatt tcagattttt atcaatttat atttaagtaa gaactcaata
    28321 tgttaaaatg aaggtggagt cattgcccag actgagatac atacctcatc atcataattt
    28381 tcatacacat gtggtatagt actgttaaaa taaaaactat ctccttcctc caatagatat
    28441 tccttatttc caagtgttat cttcatttta ccttttatta tatagccaca ttcttctcct
    28501 tcgtgtgtca caaattcact gtttttttgt gtatgaccat ctagcgtaac aagtataaat
    28561 tctatttttt tcccagataa attaggaaca agaagttcat aaaattttgt agaatcatta
    28621 gttactattt tttttcgatt atttttcttt actactatat cagagtcttc tcttccaatc
    28681 tcttcaaaaa aataacctat atttatatca agagcttttg atattttcca cattgctaca
    28741 atagatggaa caaccatatt acgctcaatt tgacttatta agcctgtact taaatctgaa
    28801 ttttttgcta aagtagagat acttatattt ttagattttc taagagatct aattttgctt
    28861 ccaacatcta tattcattag atacaaaccc cctcagacat gattataaca tataatttat
    28921 aaagattaat aaaataaaaa aaaagtttta caatacaagt attttttatg ctatattgaa
    28981 ttttctgaaa agatgcatta taatagtatt aatattcaat atattgaata ttgataacga
    29041 tattttaatt taatgaaatg gaggtaatta agatgaagag ttttgtaagt cctgataata
    29101 tttgggtatt atgggcagtt gtaactggat gggcagcatt tagtatttat ttggaacaaa
    29161 agtacaattg ggcatcaaaa gtgtcgggag caataatagc tcttgtagga gcaatgttat
    29221 tatcaaatct aaatattata ccagtagagt ctgttgtata tgaccaagta tggggatatg
    29281 ttgttccttt agccatagct ttattgttat atcaatgtaa cattaaaaag atatggaaag
    29341 aaagtggaag attgctcatt atatttcttg taggttctgt aggaactgta cttggagcta
    29401 tgattggatt tttggcatta aaaaatgtag taccagattt aaatattgtt gcagctatga
    29461 tgacaggttc ttatataggt ggaaatgtaa actttgctgc tatgtcaggc gcgtttgatg
    29521 cgccaggaga attagtatca gcaacagttg tagcagataa tcttttaatg gcattatatt
    29581 tctttgtctt aatagctata ccatcaattg gattttttag aaaacatttt aaacatccac
    29641 atgtagatga aatggaaagt ataggtataa ctgaaggaga aacagtagca gcaaattatt
    29701 ggggaagaaa agaaatatct ttaaaagata tagcaatagc cattggtagt gcttttataa
    29761 ttgtcgcagt atctgtagaa ctatcaactt ggtttaaagc tataatacca ttatcaaatc
    29821 cttttttagc aatgttaaat actttatttg gaaatcaata tctaataata actactttga
    29881 ctatgttgtt tgccacattt atgcctaatt tctttggtga tataaaagga gcacaggaat
    29941 tgggtacatt tttaatatat atattctttg ttgtagtagg tgttcctgct tcaataacat
    30001 taataattca aaaatcacca ttactacttt tatactgcgg aataatggta ctaataaaca
    30061 tgctagttac atttatagtt gcaaaaatat ttaagtttag tttagaagaa gctattcttg
    30121 catctaatgc aaatattggt ggtcctacaa cagcagcagc tatggcaata tcaaaaggat
    30181 ggtctaagct agtagggcca atacttatag ttggaacatt tggatacata gtcggtaatt
    30241 attttggtct tttagtagga aatattttga tataatttta cgtgaaaaaa agttgttttt
    30301 tagaaagatt tttatttatt agaaagattt ttatttaatt ggaggttgtt atgattttcg
    30361 atggacattc agatacttgg gcagatgtaa caataagaag gcttaacggg gaaaaagatg
    30421 tatttagaag aatccatctt gataatttta aaagagcaaa tatagaagga gctatttttg
    30481 taatatggat agacccacca tatgataaag agcctgaaaa aagagttaaa caaattataa
    30541 gctctataaa agatgaaatt gaagatatga aagatgttgt aaacatagta aaaaaatatt
    30601 cagatataga taaaggtata agtgaaaaca aaataaatat tttaattggt cttgaaggat
    30661 taagccatat tggaagaaat atagatttac tagattattt ttataaagaa gttggtgcaa
    30721 gacatgcatc attaacttgg aatgaacaga atgaacttgc tacaggatgt ttaggggatg
    30781 aaaatcgtgg tttaactgaa ataggtaaaa aagcagtcaa taaaatggaa aaattgggca
    30841 tgatagtaga tgtgtcacat ttaaatgaaa aatcattttg ggatttaatg tctgttgcaa
    30901 gtaagccagt tatagcttct cattctaatg ctaggagttt atgtgatgct aaaagaaatc
    30961 ttacagataa tcaattaaaa gaaatttcaa atacaggtgg attagttgga ataaatagtt
    31021 ttagaggatt tactaatagt aatcctaaga agcaagattt aatacatttg gttgaccata
    31081 tagactatat ggtaaatctt ataggtatag aacatgtatc ttttggtttt gattttagcg
    31141 attacttagg gaaagagact ataggttctt ttactggaaa tgctagtgtg ccaagtgtag
    31201 atggtcttga aagcacacat acagcacaga acatagtagt agagcttgaa aatagaggtt
    31261 ataaaaagaa agatatagag ttaatctcta gtggtaattt ttataggctc tttaaatata
    31321 tactaaaata atataataaa gaacttaaat ttataaaata gtatatttat acaaataata
    31381 tctacatatt taaattggcg ttcataattt attaaattaa attttaatgt tactagaagt
    31441 ttcaattcta gtaacatttt ttatgttaaa aacagatata gatatgtatt gacaatgata
    31501 attattattg ataaactata aaagtgaaaa tgataataat tttcatttta attaataaaa
    31561 gatttttaag gagggagaat gaagaaaagg tatttagtca taggaataat aattttgtct
    31621 tatttttctt tatttatagg agctgaagat ataaatataa tgcatatatt tgccaaaaat
    31681 cagcataaac ttatgatatt tatcatgagt agaataccaa gattaataag tatattgatt
    31741 gctggtgtag gaatgagcat agcaggtctt ataatgcaac agataagtaa gaataaattt
    31801 gtatcaccta caacaggtgc tacaatagat gcagcacaat ttgggatagt aatatgtatg
    31861 cttttagtac caactgcctc tatttttaca aagacaataa tagcatttgt attttctctt
    31921 gtagggactt ttacgtttat gaaaataata gggaagttac aatttaaaaa tataatcttt
    31981 gtaccattag taggtataat gtttggaaat ataataggtt ctatgacgga ttttatcgcg
    32041 tataaatacg atttgagtca aaatgttagt tcttggatgc aaggtgactt ttctatgata
    32101 cttaaaggaa attatgagat attatatatc acaatacccc ttataatatt agcatatatt
    32161 tatgcaaata aatttactgt tgttggtatg ggtatggatt ttgcgacaaa cttaggtctt
    32221 agttacaaaa gaattgtcaa tataggtctg ataatagtag cacttgttac agtatgtgta
    32281 gtcgttacag ctggtaatat cccttttata ggtctaatag ttccaaatat cgtatccttg
    32341 tatatgggtg ataatataag agcaaacata tggtatactg gtttacttgg agcgatattt
    32401 gtacttatat gtgatatttt tggaagaatt attatttatc catatgaaat atctataggg
    32461 cttacagttg gagttatagg aagtatacta ttcctttatt taatattaag gaggaatgta
    32521 aatgaagctt agtctcaatc aaaaaattta ctttgtaagt atattactat tcatatcaat
    32581 agcacttttt ataatttatg gaatagacat gaatcattta gaatatgcat tatcacaaag
    32641 aataccaaaa atatttgcta tggtattagg tggaggatgt atagcattta ctactgtagt
    32701 gtttcaaaca attacaaaca atcaaatatt aacaccaagt gtactaggtt tagattcatt
    32761 gtatgtaatg attcaaacta taatagtatt catatttggt tcaagcagta gtctgattat
    32821 aaatgaaaat tataatttta ttattaatgt agctatgatg attggagctt cattgttatt
    32881 atataagatg ttatttgaaa aaaataaaaa taatattttc tttttaatcc tagtaggaat
    32941 gatatttgga accttattta aaagtgcaac aacatttatt caggtaatga tagacccgaa
    33001 tgaattttta gctttacaaa ctagtataat ggcaagttta aacaatataa acactaatgt
    33061 attgttaata gcatttataa taattattgc cataatacct tttatatatg atgaaataaa
    33121 gtatttagat gtattgtcgt taggtaaaga acaagcaatt aatttaggtg tagattttga
    33181 taaagcagtt aaaaaaatga taatattaat agcaatttta gtctcaatat caacagcact
    33241 tattggacct atgacatttt taggactttt acttgctaat ataacaagag aaatttttaa
    33301 aacatataag catacatact tgatttcggg ttctatgttg atagggatga ttacattgat
    33361 aataggtcaa ttttttatac aacatgtatt taagtttgat acaactttaa gtgtagtaat
    33421 aaattttata ggaggaattt actttattca attactatta aagggggcaa atagatgata
    33481 gagataaaaa atatatttaa aagatataag aataaaaatg ttgtagatga tgtctctttt
    33541 agtatagaaa agggaaagat aacatctttt ataggaccaa atggagctgg aaaaagtaca
    33601 gtactatcaa tagttacaag acttatagga ggtgatggtg gagaagtaat aatagaagga
    33661 aaaagcttga ctaattatag caataaagaa ttagcaaaaa aaatagctat tcttaaacaa
    33721 tctaacaata taactttaaa gcttacaata agagaattag ttggatttgg aagatttcca
    33781 tatagtgaag gtaatctaac taaagaggat gaaaattata ttgatgaagc aatagaatat
    33841 atgaagttga ctgatataca acataagtat ttagatgaat tgagtggagg tcaaagacaa
    33901 agagcttata tagcaatggt aatagctcaa gatacagagt acatattact tgatgaacca
    33961 ctgaacaatt tggatatgaa ccattccgta cagatgatga aggtacttag aagtctttgt
    34021 gatgagttag ataagactat agtattagta atgcatgata taaattttgc atcatgttat
    34081 tcagataata tagttgcatt aaaaaatgga aaagttgaaa aagtaggtcg tacagatgag
    34141 atagtaaatg aaaaagtttt agaagatatt tatgagatga attttaacat taagaatata
    34201 aatggaaatc gaatctgtat ttatttttaa aatattgtat atgaaaataa acttgctata
    34261 taatttttta taaagttttt aaattaaaat aaagattaat aggagagagg aaaatattga
    34321 tatgaataaa aaagcagcaa tagtagcagc agtagctatt ataggattag tgacagtgtt
    34381 tgcattaggt ggaagtaaaa agaatgaatc aaaaacatca gaaaattcaa ataataccat
    34441 aaagataact cataacttgg gagaaacaga tgtaaaatta aatcctaaaa aagtagtagt
    34501 atttgattat tcggctttag atacaatgga tgcattaggt gtagctgaga atttagtagg
    34561 acttccaaaa gcgagtttac cagcatcttt agaaaaatat aaggatgaca agtatgcaga
    34621 tttaggagga ttaaaagaac cagatttaga aggtataaag tcggcaaatc cagatttaat
    34681 tataataaat ggaagacaag aagattttta tgagcaattg tcaaaaatag caccaacaat
    34741 aagtacaagt aaagatgata agaagtactt agaatctgtt aaaaataata tagacaaaat
    34801 agcaaaaata tttggagtag aagaaaaagc aaatcaagaa tttagtaaaa ttgaaaagaa
    34861 aatagaaact ttgaataaaa aagtaacaga taaaaattta aatgctttaa ctataatggt
    34921 aaatgaaggt aatttaagtg tatttggtga agaatcaaga tttagtatat tatacaatag
    34981 ttttggattt gaaaataaag ataaaaatat aaaagaatca agtcatggac aaaatattac
    35041 ttttgaatat atagctaaac aaaatccaga agttatgttc gttatagata gaggaatagc
    35101 tactggcagt gatgtaaaag aaagctcaac tgcaaaatct gttttgaaca atgatataat
    35161 aaaatctatg gatgcatata agaatgataa tataatatat ttagattcac caacatggta
    35221 tgtaaatgat ggtggtctaa catctttaaa taaaatgata gatgatgctt caaaagcggt
    35281 aaattaataa tccaatataa ccaaaatgta ttttttataa aatgattatc aaataaacta
    35341 ggagttttta agaactccta gtttattttt tgcataaaaa agatatagtt taaacaataa
    35401 tattatctat aataagataa atctattcaa aatctaataa aatatgaagt tatactagac
    35461 aaaaagaata actcttaaat ataattaagt tatataataa tatataatta taatgatata
    35521 attttaatag gtggtttgta attaaaaagt ttataaatta cattaagagt aataatctat
    35581 aagaacttat atattagaaa aaattttgta tatatagagg actctaaaga tgaactatgt
    35641 aaaacaaggt ttatatattc taattgtata gaaaatttat tgtaaacgca tgtatattat
    35701 tagaaaaaat agtttgaagg tattcaataa acataaaaaa caatataggg gataaaggtg
    35761 ttttatgaag agatttttga ggagaattat cttagtttta tttattttgt tgatttttat
    35821 aagttttatt tctattaaat taattcataa tgttggagat tatggaaaat tgattaatta
    35881 tgttgggatt gttcgtggag ctagccaacg tctaactaaa ctagagatga atcatcaacc
    35941 aaatgatgaa ttaatagaat atattgatga aatcctacag gagttgatta cagggcatgg
    36001 agattatggt ttagtaatca ctgattgtaa tgaatacaat gaggacttac ttttattaga
    36061 aaaaaagtgg gaagatttaa atattgaaat taaaaaagta agaatgaaag aacagaataa
    36121 ccagttatta agtataagtg aagagttttt ttctcttgca aatgatacag tgtttaaaat
    36181 agaaaacttt tctaaagaaa aaagtaatta cttaatgact ttaataataa ttatatctat
    36241 tataggtata ttagcatgta tcatattgat tttacaatat agtaaaaaaa tggttagact
    36301 ggaaaaatta aatgtagatt taaaaaatat tgcatataaa gatgaactaa caggagtaaa
    36361 tactatagaa aaatttaaat tggatgcaaa tcaaaatatt tgtatacata aggataagaa
    36421 atttgctgta ttctatattg attttgaaaa ctttaaatac attaatgata tatttggata
    36481 tgattatggt gacatgatac tgaaaagata tgctaatctt atgatgaatg acatagggaa
    36541 atatgaaata tttgcaagag aaattgcaga tagatttgtt gcgttaagat gctatgtaga
    36601 taaggaagat ttagtggtaa gacaacgaga tgtagacaat gaactaatta atataacaaa
    36661 tgaaattaaa aataaacata gtattactgt tgttagtgga atttgttgta ttgaagatgt
    36721 aaatgaaaaa ttaagtatag atggtttaat aaatagagca aattttgcac aaaaaactgt
    36781 taagaataaa ccaggtacta attatgcttt ttataatgac agtattcgta aaaaaatgat
    36841 tgaagaaaat actatcaaga gtagaataca tgaagctatt gaaaaaagag aatttatagt
    36901 ttatttacag cctaaagtta atttacatag tcaaaaaata aattgtgcag aagctttagt
    36961 tcgttggctt actccggata aaggtattat atctccagca atatttattc cagtacttga
    37021 gaagaatttt tttattgcct tagtagataa gtatgttttt gaggaggttt gtaaatggat
    37081 tagaaagagg ttagatgaaa ataaaccttt tgttcagata tcagttaatg tttcaagaat
    37141 acaattttat aacactaaat ttgtagaaac ttattccaat atacaaaata aatacaggat
    37201 acctaaaaat actatagaaa ttgaatttac agagagtgtt gcttttgaga atcaaaaaca
    37261 tcttttggaa attatacatg atttgcatga aaatggattt acttgttctt tagatgattt
    37321 tggaaaaggt tattcgtctt taagtgtttt aaaagattta ccatttgatg ttttaaagct
    37381 tgattctatg tttttcaagg ctagtttaga taaagataaa gagaaaatag taataaaaaa
    37441 tattgtacat atgttaaaag aacttaatat cacaactgtt gctgagggca ttgaatgcaa
    37501 ggaacaagtt gaatttctta gggatattgg gtgtgattta gttcagggat ttgtatttta
    37561 taaaccaatg ccaatattag aatttgaaaa aatattggat aaagagtttg tttataatag
    37621 ctaaaatgta ctttataaaa tatgaactaa ttaagtaaaa ttattttgta ctgaataaat
    37681 ttttacttta tttacagaat aatgattatt tacagaaaag cgcgaaaagt gtattccttt
    37741 aagtgtggga tggatagcac aaatagagga gaaaaaatat tggccatata agaatgcata
    37801 ataatataaa tatttgaaag gtcagcatta tataaaaatt aaaaagaaaa taaataattt
    37861 ttctataaaa aagagactat gagaaaattt actcatagtc tcctaaataa tgtatttatt
    37921 ttcttcctgc aacccatttt aatccccaat gaaattcagt atccatttct ctatgacctt
    37981 tgaagtattt aactactttt tcaacactga atgtctcatc atttacattt tctatcaatg
    38041 ctattgaaca catattatag ccatttttat gttcatcaag tttgacaact aagtctgaat
    38101 cttgtttttg tttgattgtt acaattccat cagcttcaga ccagttagct acaccttcgt
    38161 atataaaagc ataaataagt attcttttta tatcttttat tttattacca tttattctta
    38221 aattttctcc ttgtgtatta cttcctgttc tgtcatctcc atctaattga gcaaaaggtg
    38281 gattgtctaa actaccaaag gcatttccta atgcttgaac agcacctttt acaccatttt
    38341 tcatctcaaa taggcaaccc aaatctaaat ctatattact gcttcttaaa gagccaaaaa
    38401 aacccttttt ttgtactttt tgattccaat ttaaattaac taagatttca cctaaattgc
    38461 tattttcctt ttttgtaagg tttatttttt gtcccttttt taattctata gccatagtaa
    38521 tcttcctcca caaacataga tttatttaaa tggtagcact taataagtca atattcaaca
    38581 agattagaat aataatatta aaattatact aaatatacta aaaagtagga atcacaatac
    38641 ctttgtattt ttcttcaatt aagcttcttg ctttatctga tgtaagaaca tcttgtagaa
    38701 ctttaatctt ttcactgtct ttatcttcag ttctaaatgc taaaagattt gcatactcgt
    38761 catttatagg agctgtataa attccgtttt tcttggcatc aagaccagca ggtacagcat
    38821 aagtagtatc tataaatgca gcagtcacat ctggaagaga agatggaatt tgagcaatat
    38881 ctaactcttt gaattgtatt ccctttggat tttctattat gtccttagga ctaactaatc
    38941 catccccttt aggtaacgtt aaaagtccaa tactttcaag gtatctaagg ttcttagaac
    39001 aagaagatgg gttattgctt attgcaattg tatctccttt tttaaattca tcaacagatt
    39061 ttatcttata agagtaaagt attgctgggc atacatatag ttttttacca gccattattt
    39121 tgtaaccttt ggccttaaca gcttctttta gataaggttc atgttgaaat agatttgcat
    39181 caatttcacc attatttaaa gcttcgtttg gaagtatgta atcatcaaag tttttaactt
    39241 ctaaagtata tcctttttct ttaataagtg gttttaattc ttctaataac tctcctcctg
    39301 gaactaaagt agcaccaaca acaatttttt tatcatcttt agctttagaa catccaacca
    39361 cagctaaagt tagtactaga cataataaca aacataataa ttttttgaat ttcatataaa
    39421 ttccctcctg aatataattg attagttaaa aataaaatac cattctttat cacactgcaa
    39481 aataaaaata agcctgagtt taaactcagg ctttaaaagc taatttagac tcatctttca
    39541 gtataatact gcaggattta gcaccaatgt atataaaaat atactggttg ctgggtttca
    39601 tagggccagt cccttcacca ctctggataa gaagtatcaa tttttaatta tgttataaat
    39661 attatcatga ttttttacgt ctgtaaacat aattttataa atattttaaa atctttaatg
    39721 tattttattt aacacctaaa attccagaaa ctagaatatc agtatcagca cctaagaaat
    39781 agtcatttat ttcaatagaa tccagagtat ttctcaaagc attttcttca tgccttatac
    39841 caataagttt attttctaca aatgcaacat cacattttcc aaaaaaatct ccaaaaaatt
    39901 ttatactagt tattatgcct ttatcaacat ttaaattaaa ctcaacattt ccaccagaat
    39961 attttaattc atttgaaaga gtatattttg gtgaattacc aaaattccaa tcccaagttt
    40021 cgtattttga tttagtaagc ttttctattt gttttatatc atgctcactc aaacaataat
    40081 tagtattatc agtatttgtt ttagaaagat aatccattat agcatcttta aattctaata
    40141 tgtccatttt tgaatgtaaa tgttcactta tattggttac acgagatttt acagatttta
    40201 ttccttttcc ttcaaatttt ataggtttaa cctttaatgc ttttgagagg tcatttattt
    40261 cagatgaaaa taaaagagtc ccatgatgca ttactttgtt tttgtagttg tattgagcat
    40321 ttccagaaaa tttcttgcca tctataagaa ggtcatttct tccagaaaat tcggcattga
    40381 catctagtgt tttaagtaaa tctattatgg gctgagtgaa tcttctaaaa tcactaaaat
    40441 tattattgtt acaagctata aatgtaaaat ttatatttcc caaatcatga aatacagctc
    40501 caccaccaga ctgtctccta acgacaggta tagaatattc ttttatatat tctaaattta
    40561 tttcagaaag tgtgttttgg ttttttccaa caattataga aggttcattc ctccataaaa
    40621 taaataagtc ttcatcaaaa ttttttagaa gatattcttc cattgctaaa ttaaaataag
    40681 ggtttgtttt ttcattataa attaataaca ttaaagtagt tcctccatag aattgataaa
    40741 atttttatta tgaatacaat taattttata attcgacaat aatataaaaa ctcctttaaa
    40801 ttagaaattt taaaaactac cttgcaaagt ttaaataaat aatatatact caaaatatgt
    40861 ttaataaaag tgaatagaag ggtagaggcg caataatcta tcagtactaa taaggagtta
    40921 agcacagaga gttattagga aaggagatat tgccgaagtt ttataatcga tgctttaaga
    40981 ttatattgct gggggtacat agaaaatatg tacaactgtc acaggtttat ttgtggtgag
    41041 ctatcattta aggaattata ttatatttat ttttactatt gttgatatat tgtaatgttt
    41101 aagccttgag tgtttaccac tcaaggcttt tttagtttta ttgtaacata ataccccgta
    41161 cagttcacaa aattaaaagg agagggagat ttatatgagg aacaaaaaaa ttaatattat
    41221 ttttctgacg acaatcatgt tcataatgtc aacagtaatg gtttttgcag aagaagatat
    41281 agacactatt gcactagcca atgcagaaaa atttgggatt ttaactttaa taccaccatt
    41341 agttgctata atactcgcat ttataactaa aaacgtaata atttctttac ttataggtat
    41401 tctttctggt agttttataa ttaaagctag tggtattaat gtttttgcga catttataca
    41461 ggcattttta gatttagtag acagagcttt agtatcttta gcagaccctt ggaatgcggg
    41521 gataatatta caggttttgg caattggagg agtaataaat cttgttgcta aaatgggagg
    41581 agctaaagct atagctgaag cacttgctaa aagagcaaag tcagcaaaag ggacacagct
    41641 tataacatgg tttttggggc ttttagtatt ctttgatgat tatgccaatt cactaatagt
    41701 aggtcctatg atgagacctg ttgcagataa aatgaaaata tcgagagaaa agctagcatt
    41761 tataatagat gccacagcag caccagttgc tggtttagct ataatatcta catggatagg
    41821 tcttgaggtt ggtttaatac atgatgcttt tgaaagtata agtatagatg tagatgcatt
    41881 tggtatattt ttaaatacaa taccatttag attttacaat atattaatat tagctttcat
    41941 tgtaatatca gcattattat taaaagaatt tggtccaatg agaaaagctg agataaaatc
    42001 tagaagtaga aaaattagta tagaccttga tgaaggcgta gaagagttgg atgatttagc
    42061 tccaaaaaat ggagtaaaat tgagtgtatg gaatgctata atcccaatag gaacattgat
    42121 aatagttgca ttagcatcat tttattatag tggatataca tctataatgg gaggagacga
    42181 taaggctctg atacaactat ttacaaattc tccatattct tttgaagcaa taaaagaagc
    42241 atttagtgca tctgatgcat ctagagcatt attccagtct gcacttgttg caagtttagt
    42301 tgctattata atggctgtag taaaaaagat ttttacaata tcagaagcaa ttgatgtttg
    42361 gatagatgga atgaaaagtt tagtaatcac tggtgtaata ttaatacttg catggtcatt
    42421 aagttcagta ataaaagagt taggtacagc taaattttta atacacctat tatcaggttc
    42481 actaccacca ttcttattac caagtttaat atttggttta ggagcaataa tatcttttgc
    42541 tactggaaca gcttatggaa caatgggtat acttatgcca cttgcaattc cattagcata
    42601 ctcattaaat cctgatatgt cttatgtaat agtaagtact agtgcagttt taacaggtgc
    42661 aatatttgga gaccattgtt ctccaatttc agatacaaca atactttctt caatgggagc
    42721 tggctgtaat catatagacc atgttaacac tcaaatgcca tatgctatat ttacagcagt
    42781 aatcactatt gtatttggat atataccagc tggacttgga ttgccaatat atatagtatt
    42841 accagtggca atagctgcta tatttgtagg tattcaaata attggtaaga aagttgatga
    42901 agcggaaata gaacttgtag aataaagata taaataagtt tcacctttta ttatcattat
    42961 tttgttagtt tttagataat tttaaaaagt tattgaaaat aatggcgaaa tatagtaaaa
    43021 taaaagagtg ataagcggat gtggcggaat tggcagacgc actagactta ggat
//
LOCUS       DAMJXI010000210        19092 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.guided.068, whole genome shotgun sequence.
ACCESSION   DAMJXI010000210 DAMJXI010000000
VERSION     DAMJXI010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19092
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.guided.068"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            278..1231
                     /gene="blaCDD"
                     /locus_tag="PC465_003946"
     CDS             278..1231
                     /gene="blaCDD"
                     /locus_tag="PC465_003946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HDF2651150.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNNKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKCVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            1575..2258
                     /locus_tag="PC465_003947"
     CDS             1575..2258
                     /locus_tag="PC465_003947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2651151.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTYGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            2255..4915
                     /locus_tag="PC465_003948"
     CDS             2255..4915
                     /locus_tag="PC465_003948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2651152.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWDSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAPKSKGESFKKISETTLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKISASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYDTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(5096..6277)
                     /locus_tag="PC465_003949"
     CDS             complement(5096..6277)
                     /locus_tag="PC465_003949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2651153.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTLWSKNFFYFLVISFGI
                     ISTMATVVYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGAKFIIKFY
                     T"
     gene            complement(6277..6939)
                     /locus_tag="PC465_003950"
     CDS             complement(6277..6939)
                     /locus_tag="PC465_003950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2651154.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DN"
     gene            complement(7077..7715)
                     /locus_tag="PC465_003951"
     CDS             complement(7077..7715)
                     /locus_tag="PC465_003951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2651155.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVIGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            7894..8499
                     /locus_tag="PC465_003952"
     CDS             7894..8499
                     /locus_tag="PC465_003952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2651156.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMMKSIRELDNLKYEWICMSHGTPCIK"
     gene            9003..9752
                     /locus_tag="PC465_003953"
     CDS             9003..9752
                     /locus_tag="PC465_003953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2651157.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KSDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            9749..10513
                     /locus_tag="PC465_003954"
     CDS             9749..10513
                     /locus_tag="PC465_003954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2651158.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVIDDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            10612..11433
                     /locus_tag="PC465_003955"
     CDS             10612..11433
                     /locus_tag="PC465_003955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2651159.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKKREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            11447..13111
                     /locus_tag="PC465_003956"
     CDS             11447..13111
                     /locus_tag="PC465_003956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDF2651160.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDEGYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESEDVIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVCLKPFHAVLLKAR"
     gene            13116..14990
                     /locus_tag="PC465_003957"
     CDS             13116..14990
                     /locus_tag="PC465_003957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2651161.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMIKDRETINDKK
                     VEKVNEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVFSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDVA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
     gene            complement(15201..15860)
                     /locus_tag="PC465_003958"
     CDS             complement(15201..15860)
                     /locus_tag="PC465_003958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloramphenicol acetyltransferase CAT"
                     /protein_id="HDF2651162.1"
                     /translation="MNKQKFHKINLQNWERYTHFYYFSKMTNVGFNLTIEIDITNLLK
                     ETKKRNIKFYPAYLYTITTCLNRYRELKIAYDEDELGYWNTLTPLYAIFHDDNKTFSS
                     IWTEYDENFSIFYENYLADVKEYGKNHGFLAKPNPPRNCYTVSCLPWISFKSFTVHNH
                     GLENYFFPTIEAGKYYQKDEKILLPLSITVHHATTDGYHVSCFIDYIQKMCFNTKIWL
                     H"
     gene            complement(15853..16431)
                     /locus_tag="PC465_003959"
     CDS             complement(15853..16431)
                     /locus_tag="PC465_003959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HDF2651163.1"
                     /translation="MPTKGEQTKQFIIDTSIMLFSEKGYSNVTMKDICEACNLSRGGL
                     YRHFNSPKEIFISILNTHKYYSQNLLDKGIKENISAKHMLEYFFQQQKADINGKYCGF
                     DFAIHEFAFVEKDQRDYMNKRYSSAITMLSNLIDYGQSKSEFKKCDSKSVAIHIMFLF
                     DSMKTSASILKLTNKDIDNQINIIKDMVILYE"
     gene            16792..18879
                     /locus_tag="PC465_003960"
     CDS             16792..18879
                     /locus_tag="PC465_003960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HDF2651164.1"
                     /translation="MIKVVYMRKNKKTRKMIIFGFLMCLLIVIIVFLAKFILDGLNKN
                     KPDEVFKQYMSFANKKQYEKMYDLLDEKSKSENKKEDFVLRNKKIYEGIDAHDISIKI
                     NDIKKNKNNDKVINYDSKMDTLAGEISFSNEVLLTRDRQKNYKIKWQSNVIFPELEED
                     NTVRVSKLKGKRGRILDRNGVMIAGQGLASMIGLVPGKMSDNIEDLKKLSTLLNVSVE
                     QIEKKLNASWVKENSMVPIKTIEKIKENTDGTVKEEDKELQESLLSIPGVKISNTEVR
                     VYPFGEKTGHLTGYVQNVNADILKEKEGKRYNDNSIIGKIGLENLLEDRIRGIDGYEI
                     IIADRYGDKKETLVTEPKVDGEDVKLTIDSKLQSKLYDQMKNDKGCAVVMNPKTGEVL
                     SLVSSPSYNPNEFILGMSEDRWNELNKNENKPMYNRFKARLCPGSSFKPVTAGIGITT
                     GKINPNENFGHSSLSWQKDSSWGSYKVTTLKDYGNTANMKNALIYSDNIYFAKAALKI
                     GEDVLAKELLKLGFDESMPFEFGLSSSKFGTDNKFETEIQLADTGYGQGKLLVNPVHT
                     ASIYSAFVNDGDMIKPHLEFKKAEFWKKGVFSKEAVKIIRDDLLQVVESPDGTGHSAM
                     IKGISIAGKTGTAEIKASKDDVTGTELGWFNAFTVDENSDKQYIVIAMIEDVKSRGGS
                     HYVIPIVKSVFED"
BASE COUNT         7165 a         2186 c         3185 g         6556 t
ORIGIN      
        1 attgtaatat ttaaatatta caatagtaag ttttaaatgt ggaatcaatt attatatcac
       61 aaattaaaag gaggacagga tgttattaat agttacttaa ttatcttcgc aataggttta
      121 atcaacataa ttgtactagg tgaagaaaat ataagagata cagctattca tttagtcttg
      181 tttcttataa gtagaaccta gattggagta tattacaaat aatgtctact attttaatag
      241 taggttataa atttaaatat gggagatgat ataaattatg aaaagaaaaa agaattttat
      301 ttggatagct atcttattgg ttggtgtagt tatggtaatg tattatgtag ggaaaaaaca
      361 taacgatata aatcaaaaaa ctgataagaa ttatataaaa tctgaattaa ataagtctga
      421 attaaataaa tccaaaattg aaaacaataa taaaaacaaa aaagaaaaaa ttaatatggt
      481 tgactatagt gattgttttg aaggtattag tggaggagct attttttata atactaaaaa
      541 taaagaatat aatatatata acaaagaatt aattgaaaca agaaggtcac catgttctac
      601 ttttaaaata gtttcaactt taattggttt agaaaaaggg gtaataaact caaaagaatc
      661 agttatggga tatgatggta cagagtatcc aaataaaaat tggaataaaa atcttagttt
      721 agaagaggca tttaaggagt cttgtgtttg gtactacaaa aaattgatag ataaagttga
      781 tgctaaatct gtccaaaaca ttttagatga tttaaagtat gggaattgcg atattagcga
      841 atgggaagga gatttaaaaa atggaaaggg acatttaaat ggattttggt tagaatcttc
      901 attacaaata tctccaaaag aacaagtgca aacaatggca aaaatatttg agggagatac
      961 aaactttaaa aaagagcata ttaatatttt aagagatatt atgaaaatag atgtaaatga
     1021 taaaaacata aatgtatatg gaaaaactgg aacaggattt gatgaaaaaa ataaatgtgt
     1081 ggatgcatgg tttgttggta tgctagagcg tgaaggtgac acctattatt ttgctattaa
     1141 atcagatgat tccaataaag aaattacagg gccaaaggta aaggaaattg caattaatat
     1201 aattaagaaa tattatagtg taagggaata aacttaattt tatttgtaaa tattatttac
     1261 ctatagtctg taatatttat taaataattt tactaaattg agtctatata gagcaaaact
     1321 cctttagtac ataaaatact tgctattgat tattaaattg aatacctata gatttaaagt
     1381 taataccttt taaagactat gtaatatatt aaaagtataa ataaaatata ttgcatagtt
     1441 tttgttttat attataattt taaataatgt gcaaaaacta aacaatattt ttaatagtaa
     1501 tttatatttg tattcatgtc actataatgt cattttaggt tgctaaaatt taaccataaa
     1561 ggagatgatt gtatatggaa atattaaaat gtgaaaatct cacaaaaata tatggttcaa
     1621 atcaaaccag agtgacagcc cttaataatg taaatttatc agttcaaaaa ggtgattttg
     1681 tatccattgt aggagcatct ggttctggca aatctacatt gctacatctg cttgggggag
     1741 tagatagacc tacatatgga aagatttatg ttgaagatac agaaatatca agtttaaagg
     1801 aagaagctct tgcagttttt agacgtagaa aagtaggtct tatttatcaa ttttataatc
     1861 ttatacctac tcttgatgtt agaaaaaata tattattacc catgttactt gataaaagaa
     1921 aggtggatga ggatagattc tctgagattg tatctatatt gggattatct gatagattaa
     1981 accatcttcc aagtcaactt tcaggtggac aacaacaaag ggtatctata gctagaagtt
     2041 taatttatag accagctatt ttattagcag atgagccaac tggtaatctc gatagaaaaa
     2101 attcagaaga aattgtagat ttgttaaact tatcaaataa acgatttaat cagacaatac
     2161 ttcttattac tcatgatgag aaaatagcac tagaggcaaa tcgtattgta actatggaag
     2221 atggagtgat tgtctctgaa aaggtggtga agaaatgaat attcttcaag aatacacctt
     2281 agactttgta cgacgcaata aacgtagtag tatagctata atgttagcta tattacttac
     2341 tacaaccatg atgtcttctt tgtgtggact gttgtatacc atgtggacag attttataag
     2401 actttcaatt gagaaagaag gtaactggca tggtgaattg tttgactata cttatggaag
     2461 tgacttacca ttaattgaaa atttttcttc agttgatgat gtaatggtaa aaggacaatg
     2521 gtatgtaggc aaaattaatg atgagaaaag agattatata atttatagaa atgctacatc
     2581 agagtattgg gattctatgc cagaaaagga tactataata gagggtcgtc gaccaaataa
     2641 tgctaatgaa attgcattat caaaacaata ttttgagaat aatccaagtg taaaaattgg
     2701 tgataaaatt actctcccaa taggagatag aatcctaaat ggaaagcctc ttgaacccat
     2761 agccccaaaa tcgaaagggg aaagttttaa aaaaatttca gagactacat tgacaatagt
     2821 aggaaaggta gatgtttcta cttcatcagt aatacctgca tatacagctc ttggatatct
     2881 tgataaaaca agtataaaac ctaatgatag tataactgtg tacttgcgat ttaaaaatat
     2941 aagagacacg tataaggaac ttccaaaact tgctaaatca ttggggtgga agactaatga
     3001 atatggaaaa tacaatctta aatacaatag taattatctt ttaaagatgt tagtcttttc
     3061 accagaacag aaagcatcta tgagtagtat atcaaaattt tcaactccta ttatgtatct
     3121 tacaatagca atttttacag tagccgtgtt tgtaatggtg atttacaacg cgttttcact
     3181 gtctgcaaat gctagactta ctcagttagg gatattatct agtgttggtg catcaccaaa
     3241 acaaattaaa aggtctgtag tgtttgaagg atttttactg acaattatac cattaccaat
     3301 aggtttattt ttaggatggt tattgtgtaa taggcttata gtttatgtta attcagttaa
     3361 ttatcatact gatgttccag aagtggtatt tacttatggt attcctgctt ttctgccagc
     3421 agttttactt acaatagtaa cagtctggat ttctgcactt ataccagcac gaaaagtatc
     3481 aaagatatct cctatagaag caatacgaca aggagatagt gttaaaatca aaaagtcgca
     3541 taaatattca ttaggaaaga tatttggaat agaaggagaa cttgcatcaa acgcactacg
     3601 tgctcgtaaa aaatcttatc gtactgcaac aatatcttta acattatctt ttttattact
     3661 tacatgtttt ttgcatataa ttgcaaatca agaaggagca aaagctgttt atggaagtga
     3721 taattataag gaccaaagag atatagcagt ttatttggaa aatagtgaac ctgtagagtc
     3781 tgctttcatt gaaaaattag ataatacaga aggtgtaaaa agttcactat attatcaaaa
     3841 aatatctgct tccacttggc tgactgaaaa agatgcatca aaagaacttg cgaaaaatgg
     3901 aggatttaaa agtatagttt catctaaaaa atactctcct atagaacgtg atggcaagtt
     3961 tcgtataatt tcaaatataa ttgggcttga tgataagagt tttacagaat attgtaggca
     4021 aatttctgta gacccaaagt tattttatga tacaaaaaat ccaacctcaa ttgtatataa
     4081 taaggaggaa gatattaatc gtagtacacg tagaaataaa gtatatatag attatttaaa
     4141 tctttcaata ggagataaca ttaaattaaa tgaaaaagta tatgacgaag ataaagggga
     4201 ttatacttac aacatgaaag tgggagctat tacaagcaca cttcctaaaa tagtagatac
     4261 tagttcaaaa tatacattaa tgcaaatagt gccaatgtct atggtgcagg aaatatctaa
     4321 aaattatgat gaagtaagta ggttacgttc aaataggctg ataggagtat ttaaagtaaa
     4381 taatcgtgag gacattccta gagtaagaga aaaattagag tccatttata ataaagacta
     4441 tggttcagga gattatagta ttgaggatgt tttagaaagt gaaaaacaaa aggctagtgg
     4501 aataaagacc atgaatttaa tagtaggctt tattacaggt ttattggcta tgattggatt
     4561 atcaaatgta cttgctacag tgtcaggaaa tattagaagt agacgacaag agtttgctat
     4621 gttgcgttct gttggattat ctccagaagg cataaaaaag atgcttattt tggaaggttt
     4681 attcttagga attacaccat tactacttag tattcctgtg caaataggaa tagtgtatgc
     4741 ttttctacgt ataaatgaaa tatattttat agagtattta ccatttgcac ctatatctac
     4801 aataataggt tttactatat tgatactttt tattgtaata gcatcatata tgacaggata
     4861 caagcagttg aagaatgaaa atatagtaga atctataaaa aatgaaacaa tataaacaaa
     4921 atctatttga acttatttaa aggtttcgat ttaagactac ttacaagtat agggatagtt
     4981 aatttgtttg tttaataaaa ccttaaatgt aaatagaagt atattactaa aacaatagat
     5041 aacatagaat atagatatag ctggattata ggtattttac ctataatcca gcattttatg
     5101 tgtaaaattt aattatgaat tttgcaccac cattatggca attttctgca tgtagagtac
     5161 cattttgacg ttctataata gactttgata gagcaagccc tataccaata ctgtccttac
     5221 tagcattttt accacgataa aatctattaa aaatatatgg aagttcttcc tgagcaaacc
     5281 ccttaccatt atcttctatg ataatctcaa catatagagg attttgacta taataagcaa
     5341 ctatatatcc accatcttct atatgctcac tacaattttt aagaatattt aaaagagctt
     5401 ctaaagtcca attaatatcg atttcaaatt ctaccgaagg agaagcctcg atagtaaatg
     5461 tctgatgttt ttctcttaaa gaaccttcta taggctcaat tgcataagta agaagagaat
     5521 gtacatctat aagtttgctt tcaaatatta aagtacttgc atccaatttt gataatgtaa
     5581 gtaaagatga aactagtctc tcaagtcttg agatttgatt tgtaagcctg ttaatataat
     5641 ctatttcttc atctggacaa ttttctgaaa gtaattgtgc cataagtgac atagaagtaa
     5701 ttggagtctt aagttgatga gcaatatctg caagattatc tgaaagagtt tgtctttctt
     5761 ttaaagcaaa ttcttttgaa caacgaagtt ccccaactgt tttatatatc tcatcttcaa
     5821 ggtgagaaaa ttcatcttca catcgtaaaa gtacagactc ttttcctaaa ttcacttctt
     5881 ctaagtattg agtaagattg tttattctac tcagtttttg cttatttgtt ctatgtttga
     5941 ttatatatac aactgtagcc attgttgaaa ttataccaaa cgatatcact agaaaataaa
     6001 aaaagttttt actccaaagt gtacttttag aatatccatg ttttgataaa atttcatttc
     6061 ctgttttaaa atccttatca ctagaatttt tcagtgattt tagtatactt tctgtagact
     6121 taggattgta ctcatatgat gcaccaagag ccttagacag tacattgtat tcattaaaag
     6181 aagttatagt tgttagaatt acactcaata aaaaagttac aattaagcag aatattataa
     6241 aaacaactgt actgttgata tttcttggag ttttcactag ttgtcctcca ttctatatcc
     6301 tatgcctctt aatgttttta tacaaggtgg attttttaat ttttctctaa gacgttttat
     6361 tgtaacagta agagtgttat catttacgaa attaccatct acatcccaga gcatttctag
     6421 taactttgta cgagtcatag ctctattttt attttccata agacttagaa gaagtttata
     6481 ttctcctgct gtcaaaggta cttcaacatt atctaaatat gctttgactt caaccttatt
     6541 caagcttata ttttcacatg taatagtatt gttagtattt gaatgagttc ttctaagaac
     6601 tgcattaatt ctggattgaa gtactgagag caaaaacggt ttaaccacat agtcatctgc
     6661 acccatatct aatccacgta taatgtcttt ttcatcatca cggactgtca aaaatatcac
     6721 tggagtatct tctatacttt taacatattg gcaaaactcg tatccaatac catcaggtag
     6781 atttaaatca agcagaatta aatcaatagt tttatcaaaa ttttttttag cttcagcaat
     6841 cgtattataa caacatacag tgtgattttt cttttcaagg gaagttttta ttccaaatgt
     6901 aattgtatca tcatcttcta aaagaagtat tttagccatt tacttttaat cctttcagta
     6961 atttagttat tccattaact aagttattag ttttatgttt aatatttttt atattagaga
     7021 tagaaaaaat tatcatttaa atttaagtat ataaacttta atttataaac ttaggtttat
     7081 gctttaattg aatctattaa aagagcaaga gttgtttcaa taaatttttc ctcatctata
     7141 ttaaagttgt tcaggtatga ttttcctatt acagatagta aattaaaaaa tcctgtaagt
     7201 gtaaatattg atgaatacat aagagtaggt atttcaatat catgcctaat acttctatca
     7261 ttttttccaa tttcaaacat tccttgtatt tcatcaaaca taaatttatt aaaagaaaaa
     7321 aacttttctt taaacagcat atcagtatcc gatttttcag agtttacaat accaatcatt
     7381 cccataaggc ataatagaga aggttctaca gagtaaaatt tatgaaaagc aaagtatgaa
     7441 agttttattt tttcaaaccc tgttttgcct tttgcacttt ctattttaac attatcccaa
     7501 agtcttttat atcctcttaa gacaacagca aagaataaat cttctttaca tgaaaagtac
     7561 ttgtatatgg tgcgtttagt atattcaact tcttttgcta attcattcat agttgtatta
     7621 tcaaatccat taagacaaaa taatttttct gccttatcaa taatctcatt ttctctttgt
     7681 attttttctt tatctctttt tgataattct gacatataaa ttattccttt ctattgataa
     7741 aaaagtatac tgatggtata cttatgtaaa tataatactt gtatacctat agtatacttt
     7801 aataaaaaat aaaattaata tcaagtatta taactattta taactttatt aattaattat
     7861 ataggtaaaa taccaaataa ggggaattta tttatgaaga taaaagaaaa tgtattaatg
     7921 ttagatagta ctcgtggctc aaattgtttt attgtgtttg ataaagaaat tattcttata
     7981 gacacaggtc ttccttttat ggggaaaaat ataattaaag aattaaaaac acttggtatt
     8041 aaacttacag atattaagca tattttatta actcatcatg atgttgacca tatatctaat
     8101 attaaattat tgaaagaaaa aacaggagca aaagtatggg ctcatgtaga ggatatacct
     8161 tttattatag gagagaagga tagacctggg tttaagaagt ttattggaaa ggcaatttcc
     8221 agaaggctca ttaaggatgt tgaaccttat ggagagaata tgcagattgg gaatataaaa
     8281 attatccata ctcctggtca tactccaggg catgtctgca tgatttttga agatgtatta
     8341 tttgcaggtg atttagtcaa aaataagaat ggaaatatag ttccttatcc taatccatgg
     8401 aattgggatt ataaaaagat gatgaaatct ataagagaat tggataattt aaaatatgaa
     8461 tggatatgta tgtctcatgg aactccttgt attaaataat aaaaattaac atggattaat
     8521 agaggcgtag ttgcttgtat gtatgataat aatttacagc ttctttttaa tatatcatgt
     8581 atatttgtag ctgtaagcat atttataaca atacttacaa ttttgtattt taacatctat
     8641 aataatagtt ttagctttgt taactatgaa atttacttaa agaagtaaat attcaagtag
     8701 tagtaattat taaataagat aaaaaataaa tggcagatga attaaagtaa tttctaccat
     8761 ggaaaatact tttgagttag aaaaaactct attttagagt atgaagagat gaagcttccg
     8821 aagaaagcaa tatctaaagt acatgttcga aaggataagt actttttggt gcctgctttt
     8881 agcaggttat ttttatttta ataaaaataa aatcaaatga ttattttatc cttattattt
     8941 aaaactcttc cctagaaaaa gcaactaatg tatattaaaa taatatttag ggagtggaaa
     9001 aaatgagatt agaatcgtta gttaaccaaa attatgataa tttaaatgaa aatgataaaa
     9061 ttattattaa acaaatattg atttgtcaaa gagaataccg taatttttcg tgtgaaaaaa
     9121 ttgcaaatga atgtaatgtt tctagagcta ctttattaag gctttgtaga aaaattggat
     9181 tagattcatt ctctgattta aagtatttac ttaaaaataa tcaactagaa tttgttaata
     9241 atgataataa ttttcatgat gtttgcgaga attatcgact attaatgaat gaattacaaa
     9301 aaatatcatt tcaagatatt tgtaaaataa tatatgatgc agaaacaatt tatatttatg
     9361 ggacaggtaa tgaacagaaa agtttagctc aagaaataaa gagaatattt ctttcagtag
     9421 gtaaatgtgt tattgactta tttgatatag gtgaaattga atttatgaga gaatcatttc
     9481 aaaaaagtga tttatttatt attatttctt tatctggaga aacaaaagca ggaattgaaa
     9541 ttgcaaaatt tatcaacaat catatacata cgatttcttt aactaggctt gataataata
     9601 caattgcaac actttgtgag tataatctgt atgttgaaac tcaaaaactt gatacattac
     9661 aagctatatc ttatgaagtc gtaggagcat tttatgctct attagatttg cttcatatga
     9721 attacataga gtatagaagg agaaaagaat gaaaattgaa ggacttttca ataaatatta
     9781 taattcattt acagcaaatg ataagtatat ctgtgagtgt attcttaatc ataaagaaga
     9841 ttgtattaaa ctttctatag atgaatttgc agacaaatac catatatcta caagtgcact
     9901 ttctcgtttt gctcaaaaac tacaattacc tggatatagt gaattaagag ttattatacg
     9961 cttaaatgaa acagaagtag aatataaaaa tcaaagtaaa caccaattaa tggattgtta
    10021 taataaggtg atagatgata tagagaagaa ggattgttcg attatgtttg aaagaatgaa
    10081 aaaggcaaat cgtataatcg tctttggaga aggttattct caggaaagag ttgctaaaga
    10141 gatgaaaagg attttcttac caacagggaa aattatatat gatgtttatg gttatgatat
    10201 gattcaggca cttaatcatt ttataaaaac agatgatatg attttcttta tttcattgaa
    10261 tggagatgca tctacaatta ttgattttgc taaagaaatg agaatgaaag gaatttatat
    10321 ggtttctatt acaaaaatga taagtaatcc tttagcaaga ttatgtgatg aaaacctgta
    10381 tattcaatct atatctattt ctgtagataa acaactggac tacgatgtaa caacacctta
    10441 ttttatttta attgaactgc tttatattaa atacaagatg tatttagaaa gtgaacatat
    10501 tccccgaaaa tgaaaatttg tgctaaaaat gaacatattt tttaaaagat atcaaaatat
    10561 tgatatcttt ttttttgaat gctattatga ttttgatagt aagaaaggaa gatgaaattg
    10621 tacaaattat taatacttga tatagatggt acgcttagag atgaggtata tggaatccca
    10681 gaatctgcaa agcatgctat acgtttatgt caaaagaatc attgtagtgt tgttatttgt
    10741 actggaagaa gtatgggtac aatacaagat gatgttttat cattaggagt tgatggatat
    10801 attgcaggag gaggtaatta cattcaatat catggtgaat tactttataa tcaatctttt
    10861 aatcaaagat tgataaagga agttgtttgt ttattaaaaa agagggaagt tgctttttcg
    10921 attgagagtc aggaaaaagt tttcatgaat caaaaagcca aagaaatatt tgaaacaatg
    10981 aatcagttga aaggaactaa ttcttgtata aataaacaac atatccaaga aaaaataaca
    11041 tatgaaaata acattgaaga gtataagtca caagatatac ataaaatttg tttatggtca
    11101 aatgaaaagg tatttgacga agtgaaagat atactacaag ataaaatgga attagcacag
    11161 agagatattt ctagtcagta ttatgaaatt attcaaaaag attttcataa gggcaaagca
    11221 attaagagat tacaagaaag attaggagta actcaaaaag aaaccatatg ttttggtgat
    11281 ggtcaaaatg acattgtcat gtttcaagca tcagacgtta caattgcaat gaaaaatagt
    11341 catcaacaac ttaaagatat agcgacatct atatgtgagg acatattcga taatggaatt
    11401 tataaagaat taaaaagaag aaatatcata taaaaaggag taatttatgg aaaagaaatg
    11461 gtggcaaaaa gaaatcgttt atcaaattta tccaagaagc tttcaagata gtaataatga
    11521 tggaattgga gatttacagg gaattatttc tcgtttagat tatttaaaag atttaggtat
    11581 tacatcattg tggttatgtc caatttttaa atcacctatg gacgataatg ggtatgatat
    11641 tagtgattat ttggatattg caagtgaatt tggaagtatg gaagatttaa aagagttaat
    11701 taaagaaagt aaagatagag gaatcaaaat tatattagat ttagttctta accatacaag
    11761 tgatgaacat ccttggtttc aagaagcatt aaaaaatcca gaaagtcctt atcatgatta
    11821 ttatattttt aaaaaaggaa acgatttacc aaataactgg aggtctgttt ttggtggaag
    11881 tgtttgggaa aaggtagaga atagagacga atattatttt cattcttttg gtaaaaaaca
    11941 acctgacctt aattgggaaa atccaatatt aagaagtgaa ctttaccaaa tgattaatac
    12001 ctggtctcaa atgggagtgg caggatttag agttgatgct attacattca tcaaaaagaa
    12061 tttaagtttt caaagtttag aaagtgatgg tgttgatggt cttgttaaat gtacaaaaac
    12121 agttagaaat cagcctggaa tagaaaaaat gctttatgaa ttaaaagaaa atacgtttaa
    12181 aaaatatgat tgtatgactg ttgctgaagc agcaggtatt agctatgacc agttaggtga
    12241 ttttattgga gaagatggtt tcttttcaat ggtctttgac tttaaacatg ctgacttaga
    12301 tgttgcttct ggtagtgagt ggtttaaaag aatttcatgg acaattccag atttaagaaa
    12361 atgcatttta gatagtcaaa tgtatgttca ggaacatgga tgggcagcta attttattga
    12421 aaatcatgac caaccaagag ctacaacaaa gtatcttttg caatacgaaa ggaatgatga
    12481 tgcagtaaaa atgttgggag caatgtattt ctttttaaga ggaaccccat ttatttatca
    12541 ggggcaggaa ttaggaatga caaattttaa aagagatacc ataaatgatt ttaatgattt
    12601 atctagcatt gaccaatact atcgttcaat agatgaaggt tactcagaag aagaagcgtt
    12661 agaatttgtg aatttaagaa gccgagataa tgcaagaacg ccatttccat gggcagataa
    12721 agaaaatgca ggtttttcag atacaacacc atggttaaag gttattgaaa attataaaga
    12781 tattaatgca cagagtcaga ttaacaattc agagagtatt ttagaatttt ataaaaagat
    12841 gataaagttg agacaagata gtgagtattc tgattgtttg atttatggtt caatagaacc
    12901 tattgatata gaaagtgaag atgttattgc gtatagaagg caattagatt tggtagttat
    12961 tgattgttat tataattttt ctgataaacc tgtagaaata agagtagaag aaaaatatga
    13021 tattgtattc caaaatttag atgatataaa tctattaaat aaaacagtgt gtttgaaacc
    13081 atttcatgca gtattattga aagcgaggta gaaaaatgaa taaatataat aaaatagcaa
    13141 atgagcttat taaaattatt ggtgaagata atattatttc tattacacat tgtgcaacaa
    13201 gactaagggt gatgattaaa gatagggaaa ctattaatga taagaaagtg gaaaaggtca
    13261 atgaggttaa aggtgttttc tttacttctg gacagtatca aattatttta ggaacaggaa
    13321 tagttaataa agtttatgca gaagttgaaa aaatgggatt aaaaacttta tcaaaaaaag
    13381 aacaagatga attagttaaa aataatgaaa ctggatttaa gaaagttatg agaactctag
    13441 cagatatatt tgttcctatt attccagtta ttgcagcaac aggattattc ttgggattaa
    13501 agggttgttt gtttaatgat aatgtacttg gattatttgg aatgtcttct gcaaatattc
    13561 cattgtatat tcagacactt gtttcggttc ttacagaaac agcatttgct tttttaccag
    13621 caattattgt atggtcagca tttaaagtat ttggaggaac acctgttatt ggacttgtta
    13681 ttggacttat gttagtttcc ccaatacttc ctaatgcata ttctgttgct gacccatcaa
    13741 atgaaattga agcaattatg gcatttggat ttattcctat tgtaggttgt caaggaagtg
    13801 ttttaacagc tattgttaca gcatttattg gagctaatct tgaaaaatgg ttccgtaaac
    13861 atatgcctaa tgtattagac cttattttca caccattctt tgttatgcta ataacaatgt
    13921 tagttatttt attaggtgta ggccctataa tgcatacaat agaattaaaa atggttgata
    13981 tcatcagctt attgattgat ttgcctttag gaattggagg atttattatt ggatttacat
    14041 atccattagc tgttattact ggcttacatc atacttatgt aatgattgaa acatcactat
    14101 tagcaaatac aggatttaat gcccttatta ctctttgtgc aatgtatgga tttgcgaata
    14161 ttggaacatg tctagcattt atgaaaaaat ctaaaaataa tcaagttaaa caaactgcag
    14221 ttggagcaat gctatctcaa ctttttggta taagtgagcc tgttttattt gggattcagc
    14281 ttcgatataa tttaaagcct ttgattatta tgtgtgcatc ttcaggttta ggagcagcaa
    14341 tattatcaat tttacatatt caatctaatt catatggatt agcagtttta ccttcttatt
    14401 taatgtatat ctatgatgga tataatttaa tcacatactt attagtatca atatttgtgg
    14461 ttgcattctg ctttattgta acatgtttat ttggagtgcc taaagaagct ataaatgaag
    14521 atgaagacga agaattagtg tttaatgaaa ataatgaaaa ctttgtgtct ccagctaagg
    14581 ggaaaattgt tgcattagaa aatgtaccag atgaaacatt ttctaaaaaa atgttaggtg
    14641 atggttttgc tattgatatt atagatggaa aaattgtttc tcctatttca ggtaaattag
    14701 aaacagtatt ttcaagtgga catgcatttg ggattaaagg aactaatgga gaagtattaa
    14761 ttcatgttgg aattgataca gttgcattaa atggagatgg ctttgatgtt gctgttaaac
    14821 aaggagatat ggttaaacag ggagacgttc ttgttaatgt tgatttaaag agaatacacg
    14881 aattaggaaa gtctacttta acaatggtat tgtttccaga tggtaagaag gtaaatattt
    14941 tggatataaa caaggatgta aaaataggtc aaagaatatg tgttgagtag taggtgatat
    15001 gtaatgacta caaaagaaga ttatcaagag taattcaatc tttttaaagt atgagaaata
    15061 attcatttca tattaactat tggtaagttc aaagtataag aaataattca tctcatatta
    15121 actattgtaa gtaaaaaaga gctttctcat agcaaattta atttgctcat gcgacagttc
    15181 tttttatatt gtataaattt ttagtgtagc catatcttag tattaaagca cattttttgt
    15241 atgtaatcaa taaaacaact tacatggtat ccatcagtag ttgcgtgatg cactgttata
    15301 gaaagaggaa gaagtatttt ttcatctttt tgatagtatt tacctgcttc aattgtaggg
    15361 aaaaaataat tttcaagacc atgattatgt acagtaaaac tcttaaagct aatccatgga
    15421 aggcaggaaa cagtatagca gtttcttggc ggatttggtt ttgctagaaa accatgattt
    15481 tttccatatt ctttaacatc agctaaataa ttttcataga atattgagaa attttcatca
    15541 tattctgtcc atattgatga gaaagtctta ttatcatcat gaaaaatcgc ataaagtggc
    15601 gttaacgtgt tccaatatcc gagttcatct tcatcatatg cgatttttag ttctctatat
    15661 cgatttaagc aagtagttat tgtatataaa tacgctggat aaaatttaat atttcttttt
    15721 ttcgtttcct taagcaaatt agtaatatct atttctatag tcaaattaaa ccctacattt
    15781 gtcatttttg aaaagtagta aaaatgtgta tatcgttccc agttttgtaa attaatttta
    15841 tggaattttt gtttattcat ataaaatcac catgtccttt ataatattta tttgattatc
    15901 aatgtcttta tttgtaagtt tcaaaatgga agcagatgtt ttcatgctat caaataagaa
    15961 cattatgtgt attgcaactg atttagaatc acatttttta aattcacttt tagattgtcc
    16021 ataatcgatt aaatttgaaa gcattgtgat agctgaactg tatcttttat tcatataatc
    16081 acgttggtct ttttctacaa aagcaaattc gtgtattgca aaatcaaatc cacaatattt
    16141 gccatttatg tcagcctttt gttgttggaa aaaatattct agcatatgct tagctgatat
    16201 attttccttg atacctttat ccaacaaatt ttgagagtag tatttatgag tgtttaatat
    16261 actgataaaa atttcttttg gtgaattaaa gtgtctatat aggccaccac ggcttaaatt
    16321 acatgcttca catatatctt tcattgtcac attactatat cctttttcag aaaatagcat
    16381 tattgatgta tcaatgataa attgtttagt ttgttctcct tttgttggca tatgttttaa
    16441 cctccttttt aacgacataa gtgtcacttt taattatgag acacttgtgt cgttttgtca
    16501 agttaaagtt atatactata aaataattac aatagaataa ggttaattta taaaatagtt
    16561 gaagaataca aaagaatata atggaactga tttattttta agttgatgta aaaaataatt
    16621 aaataatgat aatattattg acttttaaaa cttacatgtg taatatataa gttactatca
    16681 attatactgc ttacatattt ttatgagata cttaaaaaca taataaaaac atagattagt
    16741 tatgtctata agagtatttt aaccttaaag cttacgtatg taatatatta aatgataaag
    16801 gtggtttata tgagaaaaaa taaaaaaaca agaaaaatga taatttttgg ttttctaatg
    16861 tgtctgctta tagttattat tgttttttta gcaaaattca tactagatgg actcaataaa
    16921 aacaaaccag atgaagtgtt taagcagtat atgtcttttg caaataaaaa acaatatgag
    16981 aaaatgtatg atttattaga tgaaaagagc aagtctgaaa ataaaaaaga agattttgtt
    17041 ttaagaaata aaaaaatcta tgaaggaatt gatgcacacg atataagtat taagattaat
    17101 gatattaaaa aaaataaaaa taatgataaa gtaataaact atgattctaa gatggatact
    17161 ttagcaggtg aaatttcatt ttcaaatgaa gtactattaa ctagagatag acagaaaaat
    17221 tataaaataa aatggcagtc aaacgtcata tttccagaac ttgaagaaga taatactgta
    17281 agggtatcaa agctgaaagg taagagagga cgtatcctgg ataggaacgg tgtaatgatt
    17341 gctggtcaag gtcttgcatc tatgatagga ttagttcctg gaaaaatgag tgataatata
    17401 gaagacttaa aaaaattatc tactttattg aatgtatcag ttgaacaaat tgaaaagaaa
    17461 ttaaatgcat cttgggtaaa agaaaattca atggtaccta taaaaactat tgaaaaaata
    17521 aaagaaaata cagatggtac tgtaaaagaa gaagataagg aactacaaga gtcacttctt
    17581 agtattcctg gagttaaaat atctaataca gaggttagag tatatccatt tggtgaaaaa
    17641 accggtcatt taactggtta tgttcaaaat gtaaatgcag atatactaaa ggaaaaagag
    17701 ggtaagaggt acaacgataa tagtataatt ggtaagattg gtttagaaaa tttactggaa
    17761 gatagaatac gtggtattga tggatatgag attataatag ctgatagata tggtgacaag
    17821 aaagaaactt tagtaactga gccaaaggta gatggagaag atgtaaagct aactatagat
    17881 tcaaaactac agagtaaact atatgaccaa atgaaaaatg ataaaggttg tgcagtagtt
    17941 atgaatccta aaacaggaga ggttttatca cttgtaagta gtccgtcgta caatccaaat
    18001 gagtttatat tgggaatgtc agaagataga tggaatgaac tcaataaaaa tgaaaataaa
    18061 ccaatgtaca atagatttaa agcacgatta tgtcctgggt cttcttttaa accagttact
    18121 gctggtattg gtataacaac aggaaagatt aatccaaatg aaaactttgg acacagcagt
    18181 ctaagttggc aaaaagattc tagttgggga agttataagg taaccacgtt aaaagattat
    18241 ggaaatactg caaatatgaa aaatgctttg atttattctg acaatattta ttttgctaag
    18301 gcagccttaa aaataggtga agatgtatta gcaaaagagt tgctgaagct tggatttgat
    18361 gaaagtatgc catttgaatt tggattgtct tcttcaaaat ttggcactga caataaattt
    18421 gagactgaaa tacaattagc agatactggc tatggacaag gtaagcttct tgtaaatcca
    18481 gtacatacgg catcaatata ttcagctttt gtaaatgatg gagacatgat aaaaccccat
    18541 cttgaattta aaaaggctga attttggaag aaaggtgtgt tttctaaaga ggctgtaaaa
    18601 attattcgtg atgacttact tcaagttgtt gaaagccctg atggtacagg tcatagtgct
    18661 atgattaaag gaattagcat tgctgggaaa actggtacag cagaaattaa agcatcaaaa
    18721 gatgatgtta cagggacaga acttggatgg tttaatgctt ttactgtaga tgaaaatagt
    18781 gataaacaat atatagtaat tgctatgatt gaagatgtaa agagtcgtgg gggaagtcat
    18841 tatgttattc ctattgttaa atcagtgttt gaagattaaa tttactcaat ttggaaatta
    18901 atcttactca gttgagaata atattttaga taaattgttt ttagacttct tagtaaactc
    18961 taaaataatt aaagaggttg tttcaaaata gagatagacc tcttttttat tgttgaaatg
    19021 atgaaaatat atttaacttc atacaaaaaa ttaaatagtg gcaacaattg aggatgtgag
    19081 ggagagttgc ca
//
LOCUS       DAMJXI010000211        18285 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.guided.075, whole genome shotgun sequence.
ACCESSION   DAMJXI010000211 DAMJXI010000000
VERSION     DAMJXI010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18285
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.guided.075"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(<1..658)
                     /gene="bclA1"
                     /locus_tag="PC465_003961"
     CDS             complement(<1..658)
                     /gene="bclA1"
                     /locus_tag="PC465_003961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA1"
                     /protein_id="HDF2651165.1"
                     /translation="MRNIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFFKVRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYYNLRTITWND
                     RVSMENIRGYLPVGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNYPYQILEFTS
                     SRGCNKPYILVTFEDRIIDNCYPKCECLPIRITGPMGPRGATGSTGPTGVTGPTGSTG
                     A"
     gene            complement(1336..1860)
                     /locus_tag="PC465_003962"
     CDS             complement(1336..1860)
                     /locus_tag="PC465_003962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2651166.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQVMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(1925..2677)
                     /locus_tag="PC465_003963"
     CDS             complement(1925..2677)
                     /locus_tag="PC465_003963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF2651167.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(2708..4006)
                     /locus_tag="PC465_003964"
     CDS             complement(2708..4006)
                     /locus_tag="PC465_003964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HDF2651168.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEDIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMDDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINVSQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(4023..6287)
                     /locus_tag="PC465_003965"
     CDS             complement(4023..6287)
                     /locus_tag="PC465_003965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HDF2651169.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(6542..7360)
                     /locus_tag="PC465_003966"
     CDS             complement(6542..7360)
                     /locus_tag="PC465_003966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF2651170.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(7353..8051)
                     /gene="cbiQ"
                     /locus_tag="PC465_003967"
     CDS             complement(7353..8051)
                     /gene="cbiQ"
                     /locus_tag="PC465_003967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HDF2651171.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(8054..8338)
                     /locus_tag="PC465_003968"
     CDS             complement(8054..8338)
                     /locus_tag="PC465_003968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2651172.1"
                     /translation="MSAKTKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEI
                     TKINPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(8328..9080)
                     /locus_tag="PC465_003969"
     CDS             complement(8328..9080)
                     /locus_tag="PC465_003969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HDF2651173.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAIPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(9262..9454)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(9586..11358)
                     /locus_tag="PC465_003970"
     CDS             complement(9586..11358)
                     /locus_tag="PC465_003970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HDF2651174.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(11372..12301)
                     /locus_tag="PC465_003971"
     CDS             complement(11372..12301)
                     /locus_tag="PC465_003971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2651175.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            12529..12717
                     /locus_tag="PC465_003972"
     CDS             12529..12717
                     /locus_tag="PC465_003972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2651176.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRTKRRKEVQYE"
     gene            12710..13411
                     /locus_tag="PC465_003973"
     CDS             12710..13411
                     /locus_tag="PC465_003973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2651177.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHCGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDCIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            13413..14336
                     /locus_tag="PC465_003974"
     CDS             13413..14336
                     /locus_tag="PC465_003974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2651178.1"
                     /translation="MNTSVYLLLILVLSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            14493..15416
                     /locus_tag="PC465_003975"
     CDS             14493..15416
                     /locus_tag="PC465_003975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2651179.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVIVISSQLCNDTLEDYFKKITGGEGIA"
     gene            15409..16146
                     /locus_tag="PC465_003976"
     CDS             15409..16146
                     /locus_tag="PC465_003976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2651180.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPTKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANIALGRRK"
     gene            16157..16930
                     /locus_tag="PC465_003977"
     CDS             16157..16930
                     /locus_tag="PC465_003977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2651181.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYIDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETNLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIISLLLCACLSAFILKGLKHNEKN"
     gene            complement(17471..18079)
                     /locus_tag="PC465_003978"
     CDS             complement(17471..18079)
                     /locus_tag="PC465_003978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDF2651182.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFAISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
BASE COUNT         5929 a         3134 c         2268 g         6954 t
ORIGIN      
        1 tcgctcctgt acttccggtt gggcctgtta ctcccgttgg tcctgtactt cctgtcgctc
       61 ctcttggtcc cattggacct gtaattctaa ttggaagaca ctcacattta ggataacaat
      121 tatctataat tctatcttca aatgttacaa gtatatacgg tttgttacaa cctctactag
      181 atgtaaattc aagaatctga taagggtaat ttaaagataa agctaaccca taattaggat
      241 atttattcat tgcccatgct tttatagttc ctgtaatatt taaacaaata tagttggatg
      301 tatcacttat cccaactggt aaatatcccc taatattttc catagacact ctatcattcc
      361 atgttatagt tcgtaaatta taatattcac ttattctttt aatttcaata tctacttttt
      421 ctttaaaaat atgattctta tttgaatcaa tatgaataaa taactctgct tttaatatac
      481 ttttgtcttt taatatatct ggtattctca ctttaaaaaa agtaatcaac ttttctttta
      541 caaaactatt tgaacattta cttcctatta agcaataatc taaattacta aagtttttat
      601 ctggatattt tttagatata aaagtatcat catttaaata aagtataata tttctcattt
      661 ataatccctc cattttgggt ctatatcata ctatgtttaa aatacatgct tagttacaat
      721 ataattaaaa tttatagtat taaattttta tataataatg ctgatttcta caaaaaaaga
      781 acatgtcatt agaaatttct aatagcatgt tctttttcat tattatatat tacactttaa
      841 attattcctt gactggctta gctggtgtaa actaaaccag tctttctaaa atattaagca
      901 cttttttctt attatgtttt ttaggattta ttgtctatat tattgtaaac caaagttata
      961 aaattgtaaa tagaatatat taccataaca atatcttttt ataagtaaaa attataaaaa
     1021 accttatttt tattaaatag aataaataaa ataagtttaa aaaatactga aataagtgtt
     1081 ttccacatat tttatatatt tatttaatac attattattt aaaaataaat atataaacaa
     1141 tcataataaa atttttttaa taaaacttta ttttttagtt aaaatcatac aatatataga
     1201 tttccacaat acaaataaat taaaaagtga aatgtatttg tctaaaaaca taataacatt
     1261 tcactttatc ctcattttta agtaatatat atttttaatt tttatttata actaaatcta
     1321 gtttttatat aaattttagt ttttttctac atctgagtaa tctattccaa aagtttctac
     1381 agtaacagat ttcataactt gtggagtttg tggcttatca gctgaatctg ttctaactga
     1441 tgctatttca tcaactgtat ccataccttc tatcactcta ccaaaacctg catactgacc
     1501 atctaagtgt ggtgagtttt tatgcattat gaaaaattga gaaccagctg aattaggtgc
     1561 catagttcta gccattgata tgactcctct ttcatgtttt aaattgttag taaatccatt
     1621 accactaaat tcacctttta ttgagtgacc tggaccaccc attcctgtac catttgggca
     1681 tcctccttgt atcataaatc ctggtattac tctatgaaat attattccat tgtaatatcc
     1741 ttcatttact aatgatacaa agtttttaac tgtatttgga gctatatttg gatataactc
     1801 aattttgatt tcttttccat tttccatttc tatagttact ataggatttt tattttccat
     1861 aatttattac cttccttttc attagttaaa ttacataatt acatttatta tattatactc
     1921 taaattaaag tctatcaagt atattttttc ctatttcata tccttcttga taaatagttt
     1981 tacaaaactc atcatcaaag ttaagcgtgt ctttaggagc aaattgagta ttaggtctaa
     2041 ctactattat tttatcttca tcatatactt ttttaatatc ttctggcaac tcataattat
     2101 attttgtgga tattaaaata attttatcca cattatcccc aattaatggt tcaattaatg
     2161 cactcctaat taaacctcca tctaatttga aaccatcata aattccttct tgcacatctt
     2221 tcacaaattg ttctttaaat ccaagagttg cgtttggatt tgatggtaac aacccactgt
     2281 atgaaatgct gataatggct tcattacgag gcatttttga tacgtcaaca atcttttctg
     2341 atactacttt attatcaact tcaacataat taacataaaa gttcatttct tctatattac
     2401 tatcatctag ttcccttagg ttgtctatag caggagaatt atccacagta ttatttacta
     2461 tttttacatt tccattctgg atatctttta tatttgtcca cattttctcc aagttatcaa
     2521 cattccctgt gtacaaataa tatccattta ttgctcctat tgatgtccct gaaatcgaat
     2581 aaaatttatt tattcctcca tcatacaagg ctttaactac tcctgcttga taagcccctt
     2641 ttgctcctcc accttctaaa cataatccta atttcatagt ctcatctcca aattgtttat
     2701 cttatattta tatttcaaaa aacttactaa atgttttata tatactatag tggtcctcaa
     2761 catttcctaa ttctcttata gaatgcattg ctaaaattgg acttcccaca tccacagatg
     2821 gtatatctat atgagtagaa gatattggac ctatagtact tcctcctctt tcatctgacc
     2881 tattaacaaa ttcttgatac tcaacattag cttctctaca tatattttta taaatagcta
     2941 tagaatatcc atcactagta tatgcctgac taacatttat ctttataacc ggaccttttc
     3001 ccattattgg tttattagtt gggtcatgct tttctggaat gtttggatga atagcatgag
     3061 ctaaatctga tgatatcata aaagatgaat aaatagactc aaagaatccc tctctatcct
     3121 tacccattga tatgcaaatt ctctccaata tatttaacaa catgtttgaa tctgcacctt
     3181 gtttagtaga gctaccaact tcttcattgt caaatacagc cattacattt acaccatgtt
     3241 gacctttagt attaacaaga gcattcaaac tagcatgtac cattgcaaga ttatcttgtc
     3301 tcccaataga tataaattca tcattagccc ctattaaact tcctttttca aattcatata
     3361 aaaataaatc aaaatctata atatcgtcca tatttacatc taagttagat gctatttgct
     3421 ttataagaaa attatctttt tctaatgtat catttaacat cccaactaaa ggtaacatat
     3481 ctttttgctt attatatgaa tgaccatcat ttatacttct atttaaatgt attgctagat
     3541 ttggtattat acaaattggc tttttaaagt ctataagcct ttcatttggt tttaatatac
     3601 tatcaccttt taaaactact ctaccagcta tcccaagagg tctatccaac catgtactta
     3661 atattgctcc tccatagcat tctgtattta acttcaaata agatttttca gcttctattt
     3721 ctgcatttgg tttaatacta aatgtaggag aatctgaatg agagcctatt attctaaatc
     3781 catctctttc tatatcttct gaatttacta caaaagctac tatagctgat aaattcttag
     3841 taacataata ctttccacca actcttagat tccatctttg attcaaaact aattcttcaa
     3901 atccattttt atctaagatt tccttagtac tctcgactgc atgaaaagac gacggactat
     3961 catatatgaa gtctattaag tttttagcaa agtttatact atccattcct catttacctc
     4021 cattataaaa tatttagtgt tgtatattct ttatttattt ttttaattcc ctgttggtca
     4081 aaagctatag taacatctgt accaattata gaaaccactg tcccaacccc aaatttagga
     4141 tgatgtacct tagaaccaag ttttatatca tctggattag tttctttatt agaatctttt
     4201 attgtagcat taactttatc tgcaacttta gatttgctta tagtactcat atacttttta
     4261 gtatatttat ctaacatatt ataacttgct ttagaatagc ttagttcttt ttttactttg
     4321 tacaatcttt ctatacattc ttctggcagt tcttccataa atcttgaagc tattgcaaca
     4381 tttgttttac catataatgt tctcttctct gtcaatgaca tatatagctc ttctttagct
     4441 ctagttatac caacataaca aagtcttctc tcttcttcta tttgtgaatc actcatagat
     4501 tttatagctc ttgatatagg aaataaccct tcttccatac ctgttaaaaa cacaacaggg
     4561 aactctaaac ctttggatgt atgaattgtc ataagcgaaa ccctatcatt gtcttcttca
     4621 tcatttgatt cagatgtaag tgctatactt gttaggaatg tctctaagtc tttattttca
     4681 taagtatcat cattactact ttcaaactcc aaagctatag aaataaattc tctcaaatta
     4741 tcaattctgt cttgagcttc ttcacctttg cctgttaaat ctttttcatt tttatttctt
     4801 atctctacaa gctcgtccat atatcctgta gtatccaaga ctttttctat aagtttgcta
     4861 acaggataaa cttcttttat agttctaaga gtccctataa tatcaacaaa tccacttata
     4921 cttgcccttg ccttagtaga tatatctgaa tttgtttcta tatcaattaa tactgagtat
     4981 atactttcct gttttaagtt agctctatct tcaatttttt ctatagttct aagccctata
     5041 cctcttctag gaacatttat aatccttttt atagatatat catcttgtgg attttgaata
     5101 actcttaaat acgccaacaa atcctttatt tcttttctct catagaattt tgtaccacca
     5161 tatatattgt atggaatttg acttctattt aaagcgtcct ctacaggtct tgcctgtgca
     5221 tttgctctat aaagtactgc aaaatcctta taaggtctat tttcttttct agctatttgt
     5281 gcaattgaat cagcaatgaa atcagcctct tctatttcgc taccagttaa ttgtatcttt
     5341 ataagttctc cttctttttt ttcactccaa agcttttttc tttttctttc tatattatta
     5401 gatatgactt tattagctgc atctaatatc acttgtgtag acctataatt ttgttctaac
     5461 tttacaacat gtacattgtc ataatctttc tcaaattcaa gtatgtttct tatatctgca
     5521 cctctccatc cataaatact ttggtcatca tctccaacaa cacaaatatt ttgatgttct
     5581 cttgctaata attttatcaa ttcatattga gctttacttg tatcttggta ctcatctacc
     5641 attatgtatc taaatctact tctgtaatat gctaacactt catcattagc cttgaaaagt
     5701 tctacagttt taagtattaa atcatcaaag tcaagtgcac tatttctttt taaacggtct
     5761 tgatatagcg cataaatatc tgcaatctta accattctat tatctgccat attgatatct
     5821 ttaaactgct ttggagtata aagtttgtct tttgctcctg aaattgcact tataactgct
     5881 tttggttcaa acactttatc acttaaattt aattctttta gacagtcttt aaccaatgta
     5941 acttggtctg ctgaatcata aattacaaaa cttctattgt aaccaatctt atttatatct
     6001 tttcttagta tacgaacaca gcaagaatgg aatgtactta tccacatatc cttagtttca
     6061 ggacctatat tttgttcaac tctctctctc atttcatttg cagctttgtt tgtaaatgtt
     6121 atagccaata tatttggtgc ttgtacacct ttatcttcta taagatatgc tattcttgtt
     6181 gttaatacct tagttttacc tgaaccagca ccagccagta taagtactgg accttcagtc
     6241 ttttctactg cttctctttg agcaggattt aatgtatcta aattcatatt tctcctcctg
     6301 ttaacagcca taaatatatt ttaatctaaa atatgaatta cttcaaatta taattatgta
     6361 ttatattaat agattatttc caatatatta caattaaata acatttttcc atataattta
     6421 tttcattgtt taataaaaaa aataacctta tgatttgggg aatcataagg cacctttaag
     6481 gggtctaggt taagggttat tatatataaa tctatttttt taaaataggt ttagggctta
     6541 attatttatt tgtattaagt tctctttcct tccaatactt atacaaatct tcttctttct
     6601 taaataaggg taaattcata tttctatgta cttttactaa ccatggggat tctagaccag
     6661 cttgtataat attattttca tttataaaca cattttctgc ctttccttca tcaatcaaaa
     6721 tccccttatc caatacatat atgtaatcac atatttcata cattaaattc atatcatgac
     6781 tggatattac tatttttata ttatttttat ttaatccctt tattatatct acaatagacc
     6841 tagtacttac tgggtctaaa ccagctgtag gttcatcaag taatacaatt tcattttcca
     6901 ttgctataac tgatgctatt gccactcttt ttttctgtcc atagctaaga aaatgtactg
     6961 gcctgtctat aaaatctatt ccattaacag ctactagagc tttgtttatt ctctctttaa
     7021 ttgttttttc atccatacca atgtttctca ttgcaaaggc tatatcatca tatacttttg
     7081 aataaaaaat ttgtttttct gggtcttgga acacaatacc tacatttttt ctaaggttgt
     7141 ataaacttct cttatcatat tttaactttt cttctttaaa aagaatttct ccagatgtag
     7201 gctttaatat acccattaaa ttcataaata atgttgattt tcctgaacca tttgaaccta
     7261 ttatacctat aacatttccc tttgaaaaat ccatattaat gtttaatagt gcattggtat
     7321 ttttttcata ttgatacgtt aaattattta ttttaaacat cattatcccc tactatgtga
     7381 aatttaccat catacaattt tatgtctaat gatatacaca tatcatcata ccttgtcata
     7441 agtcttttgt acagcatact tccaagaata cctaaggatt tatatgaagt ttttaaattt
     7501 atatatccaa atcttagctc ttgtgacttg tatatttctg aaaattcttc taaaaatatg
     7561 aatataaacc tatatattaa cattgataac tcgacaaaag tgtcaggtaa atgaagtttt
     7621 ttaaaaaaga atattaattg attaaaaggt gttgtaagta tacaaaaata cacacaagtc
     7681 aaacaagaca tcgctctaaa taacacatga atagacatgt caatagacgc ctttgatatt
     7741 cctacattaa aactaaaaaa ttcaaaacta tataataaat ctgctttatt aaaagatata
     7801 tttacaagag ttattcctat actaagaaat aaaaagtaca ttggtattct aagtaatttt
     7861 aaataatttt ttaaatctat tccagccaca caaacaacca aaatactcat taaaatcata
     7921 attccactta aaataaatat attttgtatt accatagaag caatcagaaa aattactcct
     7981 atggctactt ttttgtttgg atttacttta ctcaatctat ttgtatatgc atatttatca
     8041 attataagca tgattaactt ctctttcctt tttgaagacc taatatgtat cctattacac
     8101 cagcccctaa agctgcttgt gcagagaata ataaactttc tatttctcca cttggtggct
     8161 catatggact gctaaaccat ggtttgtaat ttggatttat cttagtaatt tcactttcag
     8221 cttgaccatc tgctcctcca tattcagcac ctgagttgac aagtaatggg aatataataa
     8281 gagctactac taataaaagt aataatatgt tagtttttgt ttttgtttta gcactcatta
     8341 gctttaactc ctttatcatt attttctagt atgctttttt ctccgttttc tgtaattaaa
     8401 ttatatacaa ttacagtaag tataccttct gctattgcta ttggtatttg agtcataaag
     8461 aaaattccta aaaatttaat tgctgaagcc attaccccac ctgatgggtc tgggaaagcc
     8521 agtgctaatt gtattgaagt tattgtatat gtggctaagt ctcctattgc tgctgcaaga
     8581 aatactggaa tagcattatt tccatctttt ttctttaaag ccttaaatat taggaatgat
     8641 acgattggcc ctattatcgc cattgaaaaa gcattagctc ctaaagtagt tattcctcca
     8701 tgtgctaata acaatgcttg gaatattaaa actatagttc caagaacaaa cattacgctt
     8761 ggtccaaaca ttattgctcc aagacctaca ccagtaggat gtgaacaact tcctgttact
     8821 gaaggtattt ttagtgctga taatacaaac acaaatgctc cacataaagc taataatact
     8881 ttctttttag ggtcttgctt tactatttta cctattgatt ttaatccgaa taagaaaaat
     8941 ggtataaata taactcccca tgctatagac cattttactg gtaagtaacc ttccattata
     9001 tgcattgcat ttgatgtaac tggagttaaa atgattaaca taagtgcagc tataacccct
     9061 aatttaatat tctgtttcat cttagtatcc ctctctccct ttctaataat taaaacataa
     9121 taatacatgt ctgatttatt taataaaata aaaaagccta actcgatggt taggcttcta
     9181 attttccaca atctaaatac aaacacataa aacaaacata tctgtataat tattataaga
     9241 aactttctcc atccccgaag aaattacttt aatattttag gcaggtctcc tgacttagct
     9301 tcatcctact cctcttcctt cccatgagat ataaaaaata tcatcatagt ggctaacaaa
     9361 agtttcgtct gcatcacagt agcgggggct gtaaaggaat ttaacctttt tccctattaa
     9421 tcttgcttaa agaacctata atattatata tttaattttt aaattattct taaatcattt
     9481 tctatataaa tcattgtata ccttttctgt gaaaatttct acatttttta taaattttat
     9541 tcatttttat atttttatgt atataaattc ttttttgtaa gtttattaat ttctaattat
     9601 cttctttaaa tacattgaaa ctacatcaga aaatctagtt atatctcttg aatatataaa
     9661 atcatttcca tatattaatc tttcagcttc aagttctgat tcttttcctg taaatactcc
     9721 taatactaat atattttgct ttctagcttt tctcacttca ttggctgtat ctctcaaacc
     9781 aactataccc ctataagcct tttctcctct taatgttctc tcactacttt ttcctatctt
     9841 tacatcattt ggtcttccat cgctgagaac tatcaggatt ttattttctt catctctatt
     9901 tattagacca ctacatatag attttattgc caaaccatct ctattattac cagcacaaaa
     9961 atattcaaat atattttcac tattttttat actatcatca taatctttaa atctttttaa
    10021 tattgtatag tctaaaaaac tagaaaatcc catcactcta tttggtatgc caacttctgt
    10081 tagagcattt gcaattatgt aagcttgaat tgccacattt ccctgatttc tactttgaga
    10141 gccacttgca tccaataata tatcaataac gtatttccct ttttcatttt ctatatcttt
    10201 ataaaatatt ttattattat tacttctacc aactctccaa gctctatttg ctaatatagt
    10261 accacaatca gaatatactc tacttttagc attttcttct attaaaattc ttgacagact
    10321 ttcttttaat ctctttattt gctgtctata cattctagca tgttctctaa attttcctaa
    10381 attattttct ttttgtcttg ttacatattt tagttgaaat acattattac actcacttct
    10441 aagaactcca tctgtaaagt gtattctaca accttcatga acatttctac aattttgtgt
    10501 ctcaattttt ttaatttcac ctttactcaa ataagttttt ccataataat gttctatttt
    10561 tgaatatatc ttatttgcag tgtcttcatc aacatatata actcggtctg ctgaattgct
    10621 acatttagaa tcatcaaaat cccctacacc ttctacaagc atggatgaag atattgaatc
    10681 tatatcactt tcaataatat tttcttcttc atcactataa agttcttcat acatgaaatc
    10741 agcaaatgta tcaaaattta cttctacact ttctacatta ttttcatcaa taagactatt
    10801 ttcttctcca tttaatatgt attcaaaata agttaaatat ataacatcta atgcttttaa
    10861 aatctccata atatcttgat tggtatctat atttcttata tcattaacta ttcttctagt
    10921 catactatct aatgctgggt gcttgtccat actataaagt acaaatgtgt atttaatttt
    10981 atccataata ttatcattgt gtattttggt aaaacgtgaa acaatatctt tataagcatt
    11041 tcttcttatg tcttctatcc ctggcctatc tttaatgacc ttttcttcaa ctattgtatt
    11101 taatatgact tgaattagac ccagtataat atctttgttg tatccttttc ttattctatt
    11161 tgtaagatat tttttaacta tatcccaatc tacatacttt cttctagcac ctgcaattat
    11221 tgcgaaatat agacctattt cttttgaaga gtaatctttt tctgatatat ctatactttc
    11281 attgtaatca ccagctattg tccatgatag gttattagct ctattttcaa attcataatc
    11341 atcatatatc catttcataa tctcacctat attaaatatg acttattgga aacacatcta
    11401 tactctccca tttattaggt attctagttt taattacatc tccaaccatt tctttctcat
    11461 atacatcaaa agtctttcct gtaagtccca tattaattgc aagagttggt tttaatcctc
    11521 ttcttatagt cttaagagat gccataagac cacgtaaatc aatagcttta ctagatatct
    11581 ctccattttg agacttcaat tgtaaatcta aaaatattcc tgcaaagtgt attaattttt
    11641 cttcatcagc atctgaaaat tcatttttta aaatcatcat taacttatct tcttctatag
    11701 gaggaatatc tattaccata aatctagata ccagtgcttc attaagttct tttgttcctg
    11761 catattcata attcatagtc ccaataaatc ttgttgctgg atgtagattg actctctcat
    11821 acccaggtac atcaattatt cttctatagt ctaaagctga atgtaccaca actatagcat
    11881 cattttttgc catattaatt tcatcaaata ccccaaaacc tccattaata gcacactcat
    11941 aaactgagcc tcttctaagt ttaacttcat tgtctataaa tgtatctgta cctataagtg
    12001 ttgaactgtc tgtatttata tgaaatgatg tattccactg aggtctatta aatatttccc
    12061 ctagattatc agcaagtaag ttttttcctg ttgcctttgg tcccgataat aatatatttt
    12121 cttcttctaa aatagctgct atacacatag acaagatatc tttaccataa aaataagttt
    12181 tagactttgt tactctgtat tctaaatctt tttctaatcc ataataattt ctaaaataca
    12241 gtacatcttc aataagtttt tcatctaccc cttgcaccct tagattatct attatatcca
    12301 tatttttacc ccttttatat aaatagtatt tgtttcattt cttatcacca ttttagcata
    12361 aaaggatata agctaaaatt gattttttaa tctccccatt ttaagtaaaa ccatgcacca
    12421 ttttatcact acaaaattaa gagtactact tactgatatt tcttgatttt gttcgtctat
    12481 acgtatataa tatatgctga taaattatga ggaaaggatg attgaaatat ggaatatatg
    12541 tcttgcccag aagtagcaaa aaaatggggt atttctgaaa gaagagtaca aaaactatgt
    12601 gaagaaagtc gcataccagg agtttcaaaa ctcgggtata tgtggctgat accaaagaac
    12661 gcagaaaagc ctgttgatgg tagaacaaaa agaagaaagg aagtacaata tgaatagcgt
    12721 tttaattata gatgatgaca aagaactttg tgctcttatg aaaaaatgtg ttgagcaaga
    12781 aaatttatct gctattactg cacattgtgg tgcagaaggt ctacatttgg tcgataaaaa
    12841 tagacacaca ctctctcttg taattttgga cataatgatg ccagatatag acggttttca
    12901 agttctgaaa aaaattagag aaacaagtaa tattccagta attatgctta ctgctaaaaa
    12961 tgacgaggat gataaagttt ccggactacg tttaggtgct gacgattacc taacaaaacc
    13021 gttcagcata aacgaactta tggctcgtgt caattctctt attcgtcggt atactatgtt
    13081 aaaccctgct tttataacag acacagattg cataataata aatggcatga ttattgacaa
    13141 gacaaaccga attgtttctg tcaataatat tcctgttcaa cttacaagca aagaatttga
    13201 tttacttgct tttctggctt ctaataaggg acgggtgttt accaaaaaac agatttatac
    13261 acaagtatgg gaagaagaat atgcttttga cgatagtaac atcatgtctt tcatcagtaa
    13321 attgagaaaa aagattgaac cagaccccaa ccatccattt tatattttga cagttcgtgg
    13381 tgtcggttat cgttttaata aggaggctta acatgaatac aagtgtctat ctgcttttga
    13441 tattggttct tagcctgatt attatagcgt accttgtttc tgtcctgcta cgtgtccgaa
    13501 tacaacttac acttataaaa gatgctttag aggatataaa aaatggaaac cttaatcgac
    13561 gtattttaac agatgaaaac gacattacaa aacaaatttg ctatgatatt aacgaaatag
    13621 caatcaatag ccaatttcaa cttattcagc aaaaacaatc agaacaagcc tacaaacagc
    13681 taatgacaag tctctcccat gatgtaaaaa ctccacttgc ttctttggtc ggttatttgg
    13741 aagcagtaga aagtaaaatt gttgtaggag aggaaaaaga cgagtatatc catgttgcgt
    13801 ctaataaggc tcattactta aagaattttg tagaaaatct atttgaatgg gtaaaattgg
    13861 attctaagga acaagttttt cattttgata tttttgactt gaatgaatta tcccgtaata
    13921 ttatatctga ttggatacct gttttagaaa gcagtcattt tgaatatgaa tttgatatac
    13981 cagaaataga gtacttctta cgtatagacg caaatgcata tacccgtatc attaataacc
    14041 tattacaaaa tattattacc catagtagtg gcaacaaaat gacattgaga atttttgaaa
    14101 acaaagagca agctcaaatt ataataacag ataatgggaa aggtatatct tcagacaatc
    14161 tcccacatat ttttgaaagg ttgtaccaat gcgaccattc acgagcttca aagggaaatg
    14221 gtttaggctt ggcgattgca aaggaactta ttaacgctca taagggaaat attaccgcca
    14281 acagcactcc cggtatggga acagaattta caatattgct tcctaaagcc ctgtaaaagt
    14341 acgaggcttt cttactctaa aacaagataa aagcaagatt atggcaaggt tttggcaagg
    14401 ttcatgtttt ataattctaa ttgtagttga ttttgacgtt gtatcaacta tcttttgtag
    14461 aaacaaattt attaaaagtg aggaaattat atatgaatga ttttgtgatt gaaacaaagc
    14521 aacttacaaa aatttatggg aatcaaacag tagttgacaa agtcaatctc catgtaaaaa
    14581 aaggccgaat atatggtctg ttaggacgca acggagctgg gaaaaccaca attatgaaaa
    14641 tgattttagg attgacttca atcacgtatg gcgaggtaga tgtatttgga gagaatatta
    14701 agggacgtga aaaacaggta tatccccgta tcggtgcaat tatcgaaacg ccaggatttt
    14761 atcctaatct gacaggaacg gagaacttgg agatttttgc aaaactgcgt ggtacagccg
    14821 cccctaattc tgtaaaaaga gcattggaaa ttgtaggctt accttataaa aataaaaagc
    14881 tgtttagtaa atattcactt ggcatgaaac agcgacttgg tattgccaac gctatcctgc
    14941 atgacccaga actgttagtt ttagatgagc caaccaatgg tcttgaccct attggtattg
    15001 cggagatgag aaagtttatt agggacttga gcgttgagca tggaaagaca attcttattt
    15061 ccagtcatat tctttcagaa atctcattgt tggctgatga tattggaatt atcgaccacg
    15121 gtgttctttt ggaagaaagt agtatgagtg aactagaaaa gaaaaacagt aaatatatcc
    15181 tgctacaagt ttcagatatt ccgaagacat cacttatttt agagcgtcaa tttaacacga
    15241 aggattattc cgttcaagat gactacacgt tacaccttta taacactaat ctggatatgg
    15301 gtgaaatcaa taaagcactt gtaatgcaga atgtaattgt tattagttct caactttgta
    15361 atgatacttt agaggactac tttaaaaaaa tcacaggagg agagggcatt gcttaaactt
    15421 attcaaacag aatttcttaa actgcgtcgt aggaaactta tttggctgat gttgttgtct
    15481 gctctcatta tgccgttttt cgcactacta tacttcaatt attttggtaa aacaggtgtt
    15541 gagccaacaa agttttataa atggtctgca tttggttata cactttggat tattttgccc
    15601 gttgttttgg gtatattttg caccatgctt atacacgaag aaaaccagta tgatatgctc
    15661 aaacagcttt ggattgtacc tattagtaaa atgggatact tttttagtaa atttttcgtt
    15721 gttttgattt actctatttg ttttatgctg attacagccg ttgcttctgt gttatttagt
    15781 gtactttctg gatatgtcgt atttagctgg gcaagcattt tatatttgtt gaaaaaatgt
    15841 ctagaaattg gtgtaatcac tgcttttgta atgttgccga ttttggcaat cgctacatct
    15901 caaaaaggat acattctccc aatttgtatc acattggtat atgccttttc cggttttgtt
    15961 ataatgacaa taaatatgta tttacaccct ttatccagta tgggagttat tatcatgaga
    16021 aataaagaca ttccaggtct tatattttca caggaaatta atgtcccatt agcatttctt
    16081 tgtatttgta tttggagtat tgtatcagta ttgtttgcaa acattgcact aggaagaaga
    16141 aagtgaggtg tagataatgt ggaaattact ttgggctgaa tgtcaaaaaa ttcgtcgttc
    16201 aaaaattgtt tggattacag tttttgcatc cattatgata gcagtcatag tttttgcagg
    16261 agggcaggat gtatataatg acccagattt acattatggc ttaaagagcg tttatgacgg
    16321 ttcacggtat atagacaatg caggttggta tatagacgca gtacaacctt ggtcaacttt
    16381 ttttgttctt cctgctgtca ttgccttatt aggaagctat attatttgtc gtgaagaaga
    16441 ggaggacact attaaatccc tgcgtcttat tcccataaat gaaacaaatt taaccatagc
    16501 aaaaatgatt attactttta tattcagtat acttctttat ttgttactct ttactataac
    16561 atttttgact gaatccgttt tacatttttc cgatttatcg acaaaactgg ttttaagttg
    16621 catgaaagag tattttcttg atggcatagg tgtattcttt gcaatttctc ccattattgc
    16681 cttggtatcg cgcatgaaaa aaggatattg gcttgcatta gtattcacag aagtttattc
    16741 tattgctgga ctatttgcgg gtatgtcaaa tgtcttacaa accttttttc ctattgcggc
    16801 aatatttaat atttctggat actatataac tactggagaa aaaattatgg ggagtatcat
    16861 aagtttatta ctttgtgcct gcctttctgc atttatactg aaagggctaa aacacaatga
    16921 aaaaaattga aatatgtata tcaaaatgaa aaagataaaa aaactgatta ttctaattgt
    16981 attcttgttt ctttttggca tgttacactg ttatactgaa tggaaattca acaatgaccc
    17041 acctaaaggg gtaatagaaa gaataaatga gtggactgat aagattggac tggattagta
    17101 acttatgtta attatagtga atgtaatatt agcaagttat tgtttcgtat tttaatacta
    17161 taactttaaa tatttggttt taatcttcca aacgaatata aaaaaactgt cacagaggca
    17221 acatattttt gaatatttat aaagtggtag ttttgatttt caaagctgcc gccttttctt
    17281 ctatataagc aaacttatcc tcaacaaagt gtaaaacatg gtacatttta agaaaaaagt
    17341 accacagaca caagcaataa aagaaacgcc gagaacctac aaaaacgtag tgcttatgca
    17401 gatttacgac gccttctatt ttctcaaccg tcttaatgac cttgtacaaa agaaattttt
    17461 ctaatatttt ttataatctt atcttgtgat gttttttatg tataaatgac ttaataacaa
    17521 atccaataaa aattatggat attggtataa ttagaacgag gaatttataa tcattataat
    17581 gtgacattat tcttacccaa ctctcagaaa aaatatatcc tatactgatt aatgaagtat
    17641 tccatatggt tattcccacg atagatgata ttgcaaaagt tataatattt tgacctgcta
    17701 tacctgctat aaaagatatg tatgttctac ataaagggat taatctacat acacaaacag
    17761 aaatagaaga gtatttatta aaataatctt gagatgcaaa tattcctttc tttgcctttg
    17821 gacatatctc tattatttta tttatgatag atttacctcc ccaatttccc actgtataac
    17881 aaaatatcga accaagtata cctgcaatta tacttaaaat taaaattgtc agaaatccaa
    17941 aatgatttct tgcagcaatt gctccacata aaggtaaaac aacttcgcta ggtaatggaa
    18001 aacaagcata ctcaatcata attaatacaa atacagagat taatccatat tgtaaaataa
    18061 aactattgat tacagacact tacttatcta tctcctttct tatttaaagg ttttaagggt
    18121 acatattcta aggattctca ccctatattt aaagaatcaa tctctttaaa ctattatatg
    18181 tatttacaca aagcatttat aacatacttt aaaaatagta ccttaaaata agaaacttaa
    18241 taaataaaaa aagattacgt ggctacgtcc tactctccca ggcag
//
LOCUS       DAMJXI010000212        16486 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.guided.082, whole genome shotgun sequence.
ACCESSION   DAMJXI010000212 DAMJXI010000000
VERSION     DAMJXI010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16486
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.guided.082"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(116..808)
                     /locus_tag="PC465_003979"
     CDS             complement(116..808)
                     /locus_tag="PC465_003979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDF2651183.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIEELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMMAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(834..2021)
                     /locus_tag="PC465_003980"
     CDS             complement(834..2021)
                     /locus_tag="PC465_003980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2651184.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRLPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSIFYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            2357..4234
                     /locus_tag="PC465_003981"
     CDS             2357..4234
                     /locus_tag="PC465_003981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2651185.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKKVYDEVIKIVPQSNNVGKKNESQENQGIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEIIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSSIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKAGYDVTTPVIVNNTFDFGQVVSCKSSYVSTNDNIISLVLAG
                     N"
     gene            4544..5950
                     /locus_tag="PC465_003982"
     CDS             4544..5950
                     /locus_tag="PC465_003982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF2651186.1"
                     /translation="MNTGFPKDFLLGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLEFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHSFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEILDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            5978..6826
                     /locus_tag="PC465_003983"
     CDS             5978..6826
                     /locus_tag="PC465_003983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2651187.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            7487..8179
                     /locus_tag="PC465_003984"
     CDS             7487..8179
                     /locus_tag="PC465_003984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2651188.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            8176..9111
                     /locus_tag="PC465_003985"
     CDS             8176..9111
                     /locus_tag="PC465_003985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2651189.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIYKRLKDIEEIL
                     ADVQIGDENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQVSVESEIGKYTVFTVSLPLI"
     gene            9259..10182
                     /locus_tag="PC465_003986"
     CDS             9259..10182
                     /locus_tag="PC465_003986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2651190.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            10166..10936
                     /locus_tag="PC465_003987"
     CDS             10166..10936
                     /locus_tag="PC465_003987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2651191.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVPKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPILSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            10946..11728
                     /locus_tag="PC465_003988"
     CDS             10946..11728
                     /locus_tag="PC465_003988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2651192.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVTLVVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            12105..12641
                     /locus_tag="PC465_003989"
     CDS             12105..12641
                     /locus_tag="PC465_003989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HDF2651193.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            12673..13062
                     /locus_tag="PC465_003990"
     CDS             12673..13062
                     /locus_tag="PC465_003990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDF2651194.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            13099..13485
                     /locus_tag="PC465_003991"
     CDS             13099..13485
                     /locus_tag="PC465_003991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HDF2651195.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            13612..15054
                     /locus_tag="PC465_003992"
     CDS             13612..15054
                     /locus_tag="PC465_003992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF2651196.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVEDESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            15351..16166
                     /locus_tag="PC465_003993"
     CDS             15351..16166
                     /locus_tag="PC465_003993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2651197.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINDFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKKVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEMRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
BASE COUNT         5975 a         2036 c         2992 g         5483 t
ORIGIN      
        1 tgaaatgatg aaaatatatt tgatttcata caaaaaagag tacctcataa ctaaaaagtt
       61 cactttgaga cactccattt ttatatgtta gttgcattta aggtaaaata taagtttaat
      121 catgttgaaa taactgaatt acatcttcta aatgattgta cattgatgta taacctaagt
      181 aagagtcttt actatcaaat gccatcatta tcttgttatg gtggctaatc atatccttga
      241 gagaatttct atatttaaaa ccgaagtatt ggttagaaga aactgtttta ggtattaact
      301 cataatattt tataaaaatt ggattatgag aagctaaaat tatctctttg tgaaattgca
      361 agtcagcatc ataacattct tctatcaaac catgagaaac cttatccaat tcctctattg
      421 actttaggta agtatatttt attttttgaa gttctttaga tgtagcattt aaaattgcta
      481 gtttagtagc ttcgctttcg ataagttgtc ttgctcttaa agattctaca taaaattctt
      541 gtatgttatg atttttatag atttcaccat catcaaatag gtcaactttt ttaaatcctt
      601 caactatagg acttgaataa ggcacagctc taagtattcc ttccttacag agtatattta
      661 tggcatttct tacaggtatt ctacttatgt taaataggtc agcaatcttt ctctcacttg
      721 gtaatttact attaatttta aaagttccat ttagaatgtt taatttaata taatcaataa
      781 ttttttcagt ggcatttaag cttttcataa aaactcctaa acatataatt tttttatgat
      841 tgtattatat catagttaag agttaaatct acttttttat aatatgtata agacaggata
      901 gaggccaaaa tagctataat agccaagata aagtatccat attgtattga agtatattcc
      961 gatattttac caactatcat tggaaataca gacattccta tagcataaat tgcttgaaaa
     1021 aaacccattg cagtagattt ctgatgtttt ggtacatttt tcatagactc gctagtaagg
     1081 taagaaagga gtatacctgt agatatacct ggtagtactt gtagtacaaa tattatatta
     1141 atatttttta ttgttgggac taaaaagcaa taggctgaaa ctaaaataaa aactaaagga
     1201 atccaaaatt ttggtccata cttagtacaa aatttagtag aagcaaagcc agaagaagca
     1261 acagcacaca ccatgtaaaa tatagaagat agacctatga gggtagaact agaacctaag
     1321 tttttaagaa tttgagtagt aaatgacatt gttgtagaca tttgaatacc ctgttgaatt
     1381 aatgccataa aggaaaaaaa tacaagtctt ttatccttgc agatagataa atatttttta
     1441 attgatattt tttcaggtat tttttttgaa ttatgatttt ttatatttaa ggctagaatc
     1501 gttccaataa ctgaagacaa tacactcatg atacataagg ctgtcattcc taatttttca
     1561 taaaataaag tactcataac aaatccaatc aacattccta gattgtttac caatattatc
     1621 gtacttgtag ctttttgttg atgttctgta gaaaaaaagt tggtatagtg aaccatgtaa
     1681 gaaatccaag ttgatgatga tattccagat aaaatgttag ctataagaaa accattgcct
     1741 ccaggagaaa agactcttat aagagatgct aaaccagcaa agaaaattcc agacagtata
     1801 aatattttat gtttatttat agaatcagca aatactccaa caggaagcct taataaacat
     1861 tgtgatattc catatgcacc tattattata ccaatcatat ttgtagatac attacatgca
     1921 cttaaatatg gattttggaa aggtatatat acatattgtg aaaaccagaa aaatgtaaca
     1981 atagaaagta aaagtaattt ttgattagat atttttttca tattatcctc catatggtat
     2041 ttttataatg caaataatat accatttaga ttttttaatc aagtactttc tctattaaaa
     2101 aaaatttaaa tatataatta ttatttacaa aaaaattata ctttatagtt gaattaagaa
     2161 aacgcttatg atactataaa gttaacaaat ttgaatatat aacagtagac gtgttactgg
     2221 taatgcaggc aagatcgaat caatttttat agattatcta tagagtacta tgggtataat
     2281 ctatttattt ggttcgattt ttttgtttaa ttggccataa aacaaaaagc ctatagttga
     2341 aaatggagga ttttttatgg attataaaaa tatagctcaa gaaattctac taaatgtagg
     2401 aggaaaagag aatgtaaatg aagtgactca ttgtatgaca agacttagat ttaaagtcaa
     2461 aagcgcttct aaagtgaata aggataaatt atctaaaact gaaggagtaa taactgttgt
     2521 tgagagtatg ggtcaaatac aagttgtaat tggaaataaa gtaaaaaaag tatatgacga
     2581 ggttataaaa attgtacctc aatcaaataa cgtaggtaaa aagaatgaaa gtcaagaaaa
     2641 ccaaggtata attaattcta tattatcagc agtagctggt atatttacac ctacaatacc
     2701 tgctatagca ggggttggta tgattaaagg tattttatca gttcttgcta tgtattatat
     2761 gaataaaaat ggagtagata taaaagaaac gcaaagctat attatcttaa atgctatggc
     2821 tgattctata ttctatttta tgcctattat actaggatat actgcggcta aagtatttaa
     2881 tgcaaataaa ataatatcta tggtattagg agctacactt tgttatccaa cttttactgc
     2941 tttgatggca ggtgaagaat ctgttagatt tttaggattg gcagtaacaa aagctacgta
     3001 tacatcatct gttattccaa taattattgc tatatgggct ctttcatacg ttgaaaaagt
     3061 attagaaaag tatatacctg agataattaa aataataatg gttccaactt tatcattggt
     3121 tgtaatgtta cctgcaacat tatttttatt tggaccaatc ggaatttata taggaaatgt
     3181 cataaacttt tcttataagt atatttatga attaagccca gcattgtgtg gagcatttgt
     3241 aggtgggtta tggtgtgtgt tggttatatt tggtgctcat agagcattat taccaatagg
     3301 tataagtgat gttgctcaaa caggaagaca gaatctattg gcgtttgcag gagctgcaaa
     3361 cttttcacaa gcaggggctg ctctaggagt attctttaaa actaaaaatc aaggactaaa
     3421 aacaatttct atgtctgcaa ctataacagc tttatttggt ataactgaac ctgcaatata
     3481 cggtgccaat cttagattaa aaaaacctat ggtatgtgcc gtaatatgtg gtgcatttgg
     3541 aggtgcgata atgggaatgg gtggagctta tggtaatgca tttgcaaacc aaggtgtttt
     3601 aactatacct gtatatgctg aagcaggtgc attaggtttc ttaagttatc taggtggttg
     3661 tgctatagca ttttttggtt cagctatttc aacttatcta gttggatttg aagatttgga
     3721 agagtcttct aataaggaaa attcatctat aaaagtagaa acgaaggatg gtgttattga
     3781 tataacttca cctgtagagg gcgaatgtat agaattgtca gaagtaaagg atgatgtatt
     3841 tgcttcaaaa gctatgggag aaggtatagc tgtgttacct acaaaaggag taataacagc
     3901 ccctactgat tgtgaagtag cttctttatt tccaacatta catgcaatag gattaaaatt
     3961 agataatgga gcagaaatgt taatacatgt tggaatcaat acagtagagt taaatggtaa
     4021 atactttaca aaacatgtta atcaaggaga tttagtgaaa aaaggtgata aacttatatc
     4081 ctttgatata gataaaataa aaaaggctgg ttatgatgta actacgccag ttatagtaaa
     4141 caatacattt gattttgggc aagtagtttc ttgtaaatct agttatgttt caaccaatga
     4201 taatataatt tcattagtat tagctggtaa ttaagttaat ttgactagag ataagtaaat
     4261 tgatttaaaa ggaaataagt aaatcaacaa ttaaatacat ctaaaagtaa gtttattgca
     4321 atgaattgtt aaagaaaata attaatatgg agtaaatcta ttgcaatgaa gtaacaaaga
     4381 aaataattaa tatagagtaa gtttattgta atgaattgtt aaagaaaata attaatatag
     4441 ggtaaatcta tctcaatgaa ataacaaaga aaagagttaa tatagagtga acttattgca
     4501 atgaatcaac aaagaaaata attaataaaa aggagaaata tttatgaata caggatttcc
     4561 aaaagacttt ttattgggag catcatcttc tgcatttcaa gtggaaggag cttgggataa
     4621 agacaataaa ggaaaaaccg tagccgacta taattctttt aaaaagtctc atttacaggc
     4681 agatactaaa gtcgcatcag acttttacca taattatgaa gaagatattg aattaatgaa
     4741 agaattaggg atgaaaacat atcgtttttc aatttcatgg gcaagaataa taccagatgg
     4801 tgaaggagag ataaaccaga aaggtttaga attttataat aagataatag acaaactaat
     4861 agagtgtgat attgagccat tcgtaacttt ataccatttt gaccttccat ttaaattagt
     4921 agagaaatat aatggttggg aaagtagaga aactgtctat gcttttgaaa gatttgctaa
     4981 aatatgcttt aagcattttg gagatagggt aaagtattgg caacctcata atgaacagaa
     5041 tttaattgtt agagtggagg agagaattaa tatatatgat gaaacagatt catggaagat
     5101 agataaaatg cgtgctcaga tggattataa tctttgctta gcacatgcat tagcagtcaa
     5161 tgcatgtcat gagatgataa aagaaagtaa aattggagca gcagtatcat catctgtaac
     5221 atatcctctt acttctaagc cagaagatgt atatgcagct agaatgaatg ataattttaa
     5281 agtgtactat atgcttgata tgcatcatta tggagaatat ccagggtatt atatgaagta
     5341 tcttgaaaaa agaaatatag ttcctcacat ggaagatggg gataaagaga tacttaaaaa
     5401 agctaaaatg gattttatag ctgtaaatta ttataggaca aattgtgcag aagctttacc
     5461 tgaagattca caacattcat ttggattaag agaaggaact gttgatttta gtatgtatgg
     5521 actatttaaa atgtcaatga atcctaactt agaggcctct gagtatggag cagcaataga
     5581 cccatcaggt cttagagttg ccttaaatga atattggcaa agatatcact tacctgttat
     5641 aataacagaa aatggtctag gagctaaaga tatattagaa gatggaaaaa ttcatgatga
     5701 ctatcgtata gactatttaa gaagtcatat aaatgcatgt aaactagcta ttgaagatgg
     5761 tgtagagatg attggatatt gtccatggtc atttacagac cttttaagtt cttctcaagg
     5821 ttttaataag cgttatggac ttgtttatat aaatagaact gaccatgaaa ttttagattt
     5881 aaaaagaatc aagaaagata gtttttactg gtataaagaa gttatagaga acaatggaat
     5941 agtaaaataa acataaatat atattgaggg ttttagtatg tacattacaa aggtattaaa
     6001 taattcgttg ctacttgcaa aggatgataa tgatgaagaa ataatattga tggggaaagg
     6061 cattggccat aattataagg ccgggtctga gttaaataaa aaagatatag aaaagatttt
     6121 tgttcttcat gatgaaaata taaaaaagag tattatacaa ttggcaacag aaatagatgc
     6181 agaatatttt ggtatagctc aaatgataat tgcatatgga atagaaaaat ataacttaaa
     6241 acttatgaac catatatatt tggccttaac tgaccacatt gcctttgcag tgagacgttt
     6301 taaagaaggt ataatgattg aaaatcacta tttgttcgaa atcaaggaat ttaatccaaa
     6361 agagtatgat ataggaaaat atgctattac tgtttttaag gaggttcttg gtttagacct
     6421 accagaagaa gagattggta atatagcagg ccattttata aatgcacaac aagataatcc
     6481 ttatagtgat agaaataaga gaagtgctaa aattgtaaat gctattttgc aaatagttca
     6541 ttatcacttt tctattgtat ataataaaga gtcattttat tataggagat ttgtaatgca
     6601 tctaaaggcc ttttcacaaa gatttctggc taatgaacca tcaagagaaa aaatagattt
     6661 tatatatgag caagttcaaa aaaattgtaa ggaagagtat gaatgtgtga aaaaggtagg
     6721 agcttatatg tataaggaat actccagaga attaccaaga caagaggagt tatatttgat
     6781 gattcatatt cataagattt taggagaatt atgcgaaaat agttagaata tcttaatatg
     6841 ctagtaatat tataaaaaat taaaaattaa ctgcacttta aatatgaata attgcattac
     6901 ttaagggggt tgtcttaaaa ttgatttttt taattaaatt tgaagctcaa ctcctttttt
     6961 aaacctttat atcattacaa ctttaatgtt tatacgcctg tactttagat gtatatctac
     7021 tttttacatt tctcaacatg caaacctacc attttttgca gtatgttaat tgaaataaac
     7081 cattgagtta accctaaatt tattctggac ttataggaat agttccaaag atactttaaa
     7141 atattttctg gaataattgc ttatttcaca tatgttttat tgtgatgttt tgatttaata
     7201 aattcttcaa ctctgtatat agtaaatgta ttatcatgtt tgttttattc aagcacactt
     7261 ataatacgct tgattttttc acaatgatga aatatactaa tgggtgttat aggtataaga
     7321 atcgcattac acttgaagaa gtaagtgata aatgagatat aaatcctcat atgataaact
     7381 actatttcat tgaggaacat attctaagtg atgtcaagat actacaatat gactaaattc
     7441 ctagtgataa aaaagtctac gaatgagtgt agaaagggga actaagatga ataaagtttt
     7501 aattatagat gatgataaag atctttgtat tttgttaaaa aagagtattt caattgaaca
     7561 gattgaagca aactattgcc attctgggag agatggactg gttgaacttt caaaacaaga
     7621 ttatcagtta gtagttctag acgtgatgat gccaggtatg gatggttttg aaactatgga
     7681 acaaatacga aaatatagca gtattcccat cttaatgctg acatcaaaaa gcgataatta
     7741 cagcaaagtg catggattgc gagctggtgc agatgactat ctaaccaaac catttgaaat
     7801 tacagaattt actgctcgtg tactgtcttt aatccgacgt tacacccgtt ttaatccaaa
     7861 aaatgaggag ccacagcaac tttctttcaa aggtttgttg attgaccttg accagcatac
     7921 agttactacc aatggcgaac ctatgttgct tccacccaag gaatttggtg tacttcttta
     7981 ctgtgcaagg catcagggta agattttgac aaaacagcag atttatgaag ccgtgtgggg
     8041 tgagccatat gtatatgatg acagcaatat catggctatt atcagtcgcc taagaaaaaa
     8101 aattgaacta gacccatcat ctcccatcta tttgcaaaca ataaaaggaa ttgggtatca
     8161 attcaacacg gaggtatgaa aatggatgaa caaacgataa ttcttttctt actcttgctg
     8221 tcgattggtc tactttttct ttccatattt gctttttcca agcttgggca tatttacaag
     8281 cgcctaaaag atatagagga gatactggct gatgtacaaa ttggagacga aaatcgtaaa
     8341 atactaatta agccatgtga tgttatggct ccattggttt atcagcttaa tgagattgtc
     8401 tacgattatg aaaataagtt actttctctg aaaaagtcgg ataaagctag caaacaactt
     8461 atgacaagtt tatctcatga tgttcgtaca ccattaacaa ctctgattgg ttatctggat
     8521 gctgtacaca gtggtatagt tatcgaacaa gagcgggagg aataccttga aatcgctagg
     8581 cgtagagcct acgacctcaa ggattacatt gatgttcttt ttgactggtt tcggttgaac
     8641 tctgatgaat ttacgctgtc aatagaatct gtggaaattg cagagttgtc acgcaatatt
     8701 ttgaaagact ggattcctat attccatgaa aagaaactga attttgaaat tgatattcca
     8761 gaaaatcgac taatggtaaa cctcgaccca gatggatatt cccgtgtggt caataatctg
     8821 gttcaaaatg ttcttgctca cagtaaggct cggcaaatca aaattaccat gagtgaggat
     8881 tccagaatgg tattactccg tgttgaggat gatggtgttg ggattgccag agaaaattta
     8941 ccacatattt ttgagcgact gtataagtgt gataaaggac gttcagaaaa aggaagtggt
     9001 cttggtctat ctattgtcag tcaaatggtg gagcgaatgg gtggtcaggt ttccgtagaa
     9061 agtgagattg gaaagtatac cgtatttaca gtgagcttac cattaatata aaattgtttt
     9121 tcccccatgt gacatgtata cacaggggga ttttttgtaa gttataaagt tgcaaggtta
     9181 atacaaggtt gttgcaaggt taatgtaaga ttgaggtggt atgataactt taataaacaa
     9241 aggaggcttt tattatttat gaataattta attattgaaa caaaaaatct cactaagcaa
     9301 tatggtgctc aaaagagcgt ttctaatttg aatattcacg ttcagaaagg tcgcatttac
     9361 ggattgctag gaagaaacgg tgcgggtaag acgacaacta tgaaaatgtt attgggtcta
     9421 acaaaaccaa ctactggaga aattaaaata tttggtcagg acattcacaa taacgagaag
     9481 aagcttcttc ctcgaattgg atgtttgatt gaatcaccag ggttttatcc taatctgaca
     9541 ggaacagaaa atctcaaaat ctttgcaagg cttagaggaa taccaaaaaa aaatgcagta
     9601 gaatcagcac tggatgtagt cggtttgcca aacaatgaca aaaagttatt ttctcaatac
     9661 tctcttggta tgaaacagag gttggcgatt gctcttgcca ttatgcatga cccacaactg
     9721 ttgattttgg acgagcctat caatggactt gatcctattg gtattgcaga agtaagaaca
     9781 tttattcgtg atctctgcac agaacgaggt aaaactattt tgatttccag tcacattctt
     9841 tctgaaattg ccttgttggc agatgacatt ggcattattg accatggtat tttgttggag
     9901 gaagaaagtc ttgcccaatt agaagaaaaa aacagtaaat acatacattt tgctgtatct
     9961 gatgcagcac aggcagcaag gcttctggaa acccaactta acctgaaaaa tttcaaagta
    10021 gcagataatt acaatattat gctatatgat acagatgttt ctgttgcaga aataaatcgt
    10081 gctttcattc taaacaacat tgaggtatca gaatctcatt tatgcgaaga tactcttgaa
    10141 gattacttca agaaagtaac agggggtgaa ggaattgctt gatataattt catgtgaatt
    10201 ttcaaaactc aagcggttaa aatttatact gatttctatt ttaggtgctt gcttatttcc
    10261 aattcccgca acaattttga ttgcaaagga taacttgccc tttgagcaat tgttcaaatt
    10321 agttgtcaat tttggatatt ttttgctatt accaattgta ttaagtattg ttgctagcca
    10381 actatttttt atagaaagag ataatgatgt attaaaaaat cttgcaacag tgccagtgcc
    10441 aaaaggaaaa ctggctctgg caaaattggc tgtgttgctg tttatatcat tgttctactc
    10501 tgttgcaggg ttaggagcta ctatcattgg aggtttcatt gttggaatag tagagggggt
    10561 tgctgtaaaa ttaggaatga gcattgcttt tggaattatg ttttttgtta ctgtacttcc
    10621 tgttgtggta ctcattgtat atttcaatcg cagctatatt ttttctatta tactttcttt
    10681 tgtatatgct attttcaatt ttagtatatc cttaaatatt atcaattttg aaccaaataa
    10741 cccaatatta agtgtattac ctgctcctgt tataatgcgt tggtggatgg cattttgggg
    10801 agatcccact ggcgaataca cggcacttag acagccatat ttgctctcaa ctcctgcttg
    10861 tgtaggtatt ttatgtttga taaccattat agcagtcctg ctgatttgta tgatatacaa
    10921 aaagcaggag aattaggagg tatctatgct tgatataatt actacagaat ttcaaaaaat
    10981 aaaaagatat aatattctat ggattggtgt tgttgctgtt ctgttttcag cactattggc
    11041 agtttttcag gttgtaagtt cacacggcag tgaccctcta acgtatgaga gctttgcaaa
    11101 cggagttatc tggaataatt tcagtcttag ttttccattt gggattacac ttattggagg
    11161 atatcttatt aaccgtgaat atacagacca aaccttaaaa aacatcctaa ctgttcctat
    11221 ttcattacgc aaattgctag tgggaaaatt aattgcagtt ggaggaatta ctgtattgtt
    11281 aagtcttttc agcttcttat gcacatttat tttggggttg ttattttgta atatcaatat
    11341 atctgttaca ctcgttgtaa aatccttagt tcagattttg tctgttaatc tgtattgtta
    11401 tgttgctgtt ttgccgatta ttgcttattt tggtcgtaaa caaaatgcat ttctgacagg
    11461 tgtagggatt gcatttgtat acggtttttg tggtgtgttt gttgctggaa gaaatctgac
    11521 agacttttat ccaatcacag caggtcttgg tctagttgga tacaacaatg gtgctggtac
    11581 tgtttatcag ccacttatcg gtgctatgac tttgattgta attctaatct tgacaactat
    11641 tctacttgta tttacaccta attatgataa agttatgacc atatctaaga aaaaagggat
    11701 aaagcataaa aagtattctc ataaataaca taaatattgt ttctattatt taagttgcta
    11761 gacagtgaaa agaaaaaatc tgtcgtacag tggctatatg ctcatgtatt caagaagcta
    11821 cagttttgat ttttcataac tgtagcttct ttttgtattt attaaatcac gactatcata
    11881 atacttgcaa taggtatagc gacaagagag agtactgtca tatgtgtttt atatattaca
    11941 ttaagtatat tctaaaatat atgttttaaa taatatattt gaaaatagga atatttaaat
    12001 aaaaaaaata atattatata tagttgacaa aaattggcaa atgagatact atataaatat
    12061 agaaatagta atcattacta ttattaaaaa gggaggaatt aattatgaac ttaaaaggaa
    12121 ctaaaacaga aaagaattta atggcaggat ttgcaggaga gtcagaagca agaaataaat
    12181 atacatacta cgcttcaaaa gcaagaaaag aaggttataa tcaaatagct gctatatttg
    12241 aagaaactgc taacaatgaa aaggaacatg ctaaattatg gtttaaactt ttacatgatg
    12301 gtatgccttc aacagaggaa aatttaaagg atgcagcagc aggtgaaaac tatgaatgga
    12361 ctgatatgta tgcaaaattt gctaaagaag ctagagaaga aggatttgac aagatagctt
    12421 atttatttga agctgttgga aaaatagaga aagagcatga agaaagatac ttaaagcttt
    12481 tagaaaactt aaatgaagga aaaatattta aaagagatga agaagttgtt tggcaatgtc
    12541 aaaactgtgg tcatgtgtat gtaggtactg aagcaccaga aaaatgccca gtatgtgacc
    12601 atccaaaagc atatttcaat ataaaagctg aaaattatta aaaattatca ttattaaaaa
    12661 ggaatgttaa ctatgaaatt ttctaaacaa cgagaactga ttttaaatga aatattaaat
    12721 aatccggttc atcctactgc ggattaccta tatgaaaact taaaaaaaga taatccaaat
    12781 ttaagcttag gaactgtgta tagaaattta gctcagctaa cggaacatgg ctttataaga
    12841 aaggttagta ttccagggta tccagataga tttgatggtc gaatagataa tcactatcat
    12901 atcatatgtg aagtatgtgg agaggtatac gatttagaat ccgaagttct taataattta
    12961 caagaattaa tatctgagga gacagacata aaaataacat cttataacat aagttttaaa
    13021 gggatttgta ataattgtaa aaggtgtagc caagtaggtt agttttcaaa ttctaaaaat
    13081 aattaatgag gtgagtttat gtgtagtgaa caaaaatttt ttatatgtga gacttgtgga
    13141 aaccttgtag gaatgataca aagtggtggt gtacctattt tctgttgtgg aaaacctatg
    13201 aaggaacttg ttcctaatac aacagatgca gcagttgaaa aacatgtacc tgtaattgaa
    13261 gtggatggaa ataatgttac tgttaaagta agtagcacaa ctcatccaat gactaaagaa
    13321 catcatatag catgggtgta tcttatgact gaacaaggtg gtcaacgcaa atgtctagca
    13381 gtagatggag aacctgtagt taaatttgct ttgaatgatg atgataaagt gatttctgcc
    13441 tatgcttact gtaatttaca tggattatgg aaggctgaac tgtaatattt aaataaattg
    13501 agtcaaaaag gaggctataa atgtattttc atacaaatag cctcctataa atttatataa
    13561 attcaagttt taattttgtt taatgtcaat ataatataag gagaaaataa tatgtcaatt
    13621 tataaatgta gtgtttgtgg atatatttat gatgaatcta agaatgataa aacatgggat
    13681 gaattaagtg aagattggga atgccctgta tgtacaaaag gtcgtagtta ttttggaaag
    13741 ataagtactg tttactatga agaagatgaa aagatagcag aagacatagt tgaagatgaa
    13801 tctaaattaa atactgaaaa agagggagat ttaaattact taagtacata tttaagaaga
    13861 gatgatgaag ttgagaaaca tatggatata attcacgaaa tggctgttac aggaaaatct
    13921 ataatagaac ctatgagaac taaactacca gtaatttctt gggatgatat tttaattatg
    13981 ggtgctcaat taaatccatt acctttaaat gagcatgatg aagtaaatac aacaacaata
    14041 ataggaaaaa aagcaaagaa acctatgatt atagaaaatc cagtttatat ttcccacatg
    14101 tcatttggag ctttgtctaa agaactaaaa atagctttag caaagggtgc agcccaaaat
    14161 aagacagcta tgtgtagtgg tgaaggaggt atattaccag aagagaagga agcttcatac
    14221 aagtatattt ttgagtatgt accaaataaa tatagtgtaa ctgaagaaaa tcttaaaaat
    14281 tctgatgcta tagagataaa aattggtcaa ggaacaaaac ctggtatggg aggtcatctt
    14341 cctggcgaaa aagtaactga agaaatagca aaagtaagaa ataagcctgt aggtcaagat
    14401 gtaataagtc catcttgttt tgaggaaata caatccaaag aagatttaaa gaaacttgta
    14461 gatgaactta gagaagtttc agaagggcgt ccaataggtg ttaaaatttc agcaggtcat
    14521 attgaaaaag atatggaatt tatagcttat gctaaacctg attttgtaac tattgatggt
    14581 cgtggtggag ctactggagc aagtccaaag ttgcttaaag atgcaacttc aattccaaca
    14641 atatttgctc tttatcgtgc tagaaaatac atagatacac atggattaga tatagatttg
    14701 gttataacag gtgggcttcg tatatctact gattttgcta aggcaattgc tatgggtgct
    14761 gatgcagttg ctattgcaag ttctgctctt atggcagcgg cgtgtcaaca atatcgtata
    14821 tgtggttctg gtaagtgtcc tgtaggagta gctactcagg atgaggaatt gagaaaaaga
    14881 ttacatatag aaaacagtgc taatagagtg gcaaactttt taaatgtaag tttagaagaa
    14941 cttaagactt ttgctagaat ttctggtcat aaagatatac atgatttaag tgttgatgat
    15001 ttatatactg ttaactctga aatatcaaat tatacaaaca tacagcatgt atagattgaa
    15061 gtttgaaact attagatttt agatagctat aaaagtaaat gataaatata ttttataaaa
    15121 gagagtgtct taaaatgaac tttttagttc ataagtcact ctttttttga tgaagccaaa
    15181 tatatttatc attttagcaa tgaaaaagaa tcttatctct ttattttgag atagactcct
    15241 tctatttatg aaaattaaag atattaaatt gtaaaatatt ctgtgatgtc gtactattaa
    15301 actaaagatt ctgtacttta aagtaaataa aaatttaagg agtgattatt atggaaagat
    15361 tgaagataca agttttagtt gacaataata cttatattga tagatacttt gttggagaac
    15421 cagcagtaag ctattatatt gagattgatg gaaataggat tttgtttgac tcagggtatt
    15481 cagatgtatt catatcaaac gctgaaaaat taaatataga tttaggaaat ttaactcatg
    15541 ttgttttttc tcatgggcat aatgaccata caagaggtat ccagtttcta gaaaataggt
    15601 atgatttatc tacagttgaa cttatttcac atcctaactg ttttatacct agaaaacatg
    15661 gagagaaaag cataggagct ccattttctg ctgaggaaat taaaaatatt tttatgtata
    15721 atcctaagga taagccattt aatctaagta agaattgtgt gtttttaggt gaaatacctt
    15781 ctataaatga ttttgaaaaa agagctaaaa ttggtaaatg taaaatagga gatttgtggg
    15841 aagatgatta tgttttagat gattctgcta tagtttgtaa aactgataaa ggtattttta
    15901 ttgttacagg atgttctcat agtggaattt gtaatatagt agagtatgct aaaaaggtat
    15961 gtggagatga tagagttatt ggtatactag gtggttttca tctttttgaa ttgaataata
    16021 ggttagatag tacaatacaa tatttggata aagaagaaat gagaatgttg tacccttgtc
    16081 actgtgtttc ttttaaggta aaagcgaaga tgaatgaaat attgaatata aatgaagttg
    16141 gagtagggct gaccataagt atatagtatt tgaaagtata taagatttaa gttgaaggtt
    16201 aaaaagatat tttctataga aaatatcttt tttgttacgt ttattttaag agaaatcaat
    16261 atacttttat atgaaatatt gtaaaaaaat ttatttttaa tgagaatata ttttcattaa
    16321 taaacaattt tattatgtat taataatgtt agaataaata taaataaatc aaagttactt
    16381 acattacagt atattttttc acaaaatata ttgatttatt cttttaaagt ttgataattc
    16441 caatgaatgt aataaaagaa ggaattttat actatacgat tattat
//
LOCUS       DAMJXI010000213        11163 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.guided.102, whole genome shotgun sequence.
ACCESSION   DAMJXI010000213 DAMJXI010000000
VERSION     DAMJXI010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11163
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.guided.102"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            283..621
                     /locus_tag="PC465_003994"
     CDS             283..621
                     /locus_tag="PC465_003994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2651198.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
     gene            643..960
                     /locus_tag="PC465_003995"
     CDS             643..960
                     /locus_tag="PC465_003995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2651199.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            1110..1787
                     /locus_tag="PC465_003996"
     CDS             1110..1787
                     /locus_tag="PC465_003996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651200.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(2115..2882)
                     /locus_tag="PC465_003997"
     CDS             complement(2115..2882)
                     /locus_tag="PC465_003997"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDF2651201.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(3554..4369)
                     /locus_tag="PC465_003998"
     CDS             complement(3554..4369)
                     /locus_tag="PC465_003998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF2651202.1"
                     /translation="MVKLSDAKSWAIRMSEDGCAYKSIGNYKRSLKASFFMAIQDDCI
                     RKNPFNFQLSDVLEDTTEPKIALTPEQEMGLLSFMESDKTYCKYYDDVVILLETGLRI
                     SELCGLTLELDMKNKAIMVDHQLLSDTKIGYYVEVPKTTQGKREIPMTERAYQSFERI
                     VERRKNAKAEPIIVDGYQNFLFLKQDGLPKQATHYQSMLRALVKKYNKTHEDKLPKIT
                     PYIFMHTLCTNMANKGMSPNILQYIMGHKNITMTLGYYAHGSFSSARAEMERL"
     gene            4605..5168
                     /locus_tag="PC465_003999"
                     /pseudo
     CDS             4605..5168
                     /locus_tag="PC465_003999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729092.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            5256..5876
                     /locus_tag="PC465_004000"
     CDS             5256..5876
                     /locus_tag="PC465_004000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF2651203.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            6032..6814
                     /locus_tag="PC465_004001"
     CDS             6032..6814
                     /locus_tag="PC465_004001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HDF2651204.1"
                     /translation="MTKTQQKMIQNVLEFSKRDSRIIGLAISGSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDSPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYACTKIGRR
                     ELFETIDFLSFLRQSVLAPLIQLLLGKLPRGVRKIELDAPQYIEALEKTVANHEYKSC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            6939..7865
                     /locus_tag="PC465_004002"
     CDS             6939..7865
                     /locus_tag="PC465_004002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651205.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESNLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKISVKQGNETVEIADG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            7879..8328
                     /locus_tag="PC465_004003"
     CDS             7879..8328
                     /locus_tag="PC465_004003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2651206.1"
                     /translation="MELIEWNYAYITELVEFANDKEIANNLRDNFPHPYREQNARDFI
                     SFCLATPDVKQLSYAIFYQERAIGSISLTFEEDTSINKNAELGYWLARNYWGKGIATN
                     AIKEICKIAFEKYNLNKIHANVYSYNRGSSKVLEKCGFKIEEYCHNS"
     gene            8688..9092
                     /locus_tag="PC465_004004"
                     /pseudo
     CDS             8688..9092
                     /locus_tag="PC465_004004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897392.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
     gene            9096..9326
                     /locus_tag="PC465_004005"
     CDS             9096..9326
                     /locus_tag="PC465_004005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2651207.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINGILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            9716..9919
                     /locus_tag="PC465_004006"
     CDS             9716..9919
                     /locus_tag="PC465_004006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDF2651208.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDVI"
     gene            9997..10350
                     /locus_tag="PC465_004007"
     CDS             9997..10350
                     /locus_tag="PC465_004007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HDF2651209.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKPQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNVLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            10422..11054
                     /locus_tag="PC465_004008"
     CDS             10422..11054
                     /locus_tag="PC465_004008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HDF2651210.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
BASE COUNT         4124 a         1575 c         1741 g         3723 t
ORIGIN      
        1 attctacata tctaatatgt aattacaata aaaaatgcta taattaacat attattaatt
       61 cgttttatta ttgtagtatg gctatgaaat tatgaaaata tttctctaat taaaaatatg
      121 atttatccat atttgtttat tgtagataca gactatacaa aaataaatag cacttatttc
      181 agtataaaaa catatatagt ctatatttag actaaaaaag tataaatagt ctatataaaa
      241 caacttaaac tatgaatata atctaaagtg gagggataat aattggcaaa tataggaaaa
      301 ataataggag atagaataaa agtctataga acaaaattgg gatatagtca agagtttcta
      361 gcagaaaagg caggtttaca tccaacatat attggtcaga ttgaaagagc tgagacaaat
      421 acatctatca atattataat gaaaattgct actgctttag acataccact tgaattgtta
      481 tttgcaaata ttattacaac agaaggcgtt gataactctg tacctttaga atgttatgaa
      541 atgattaata aattaactga aaaagaacaa attgcaatgc tagagttaat aaagtgcatc
      601 attaaataca aagaaatata agtgagggaa atagtaacaa taatgaatta tataggtaaa
      661 agacttaaag aagaacggaa aaaagcaaat ttaacttcaa aagaatttgc aaatatggtt
      721 ggagtatcgc cttggtatat aactcaaatc gaaagtggta aaaagaatcc aagtcttaaa
      781 acattcataa aatttgtaaa tatattaaat atttctgcag atgttcttat aaaagatatt
      841 acttccactg gaaaaacata tttagaaaat gatataaatg aagagttaaa agacttaaat
      901 tcaagagaac taaatctgat atcacagatt atagacatca taaaaaagaa taaaatataa
      961 ttctttatat tttatataaa aaaaaaggtt atttgaaata aataaccttt ttttgtcttt
     1021 ttgtgttaac attgtcttat agtgctaatg agtactatta gaccatgttc tatggcctta
     1081 ttttaatata aaacgattgg agataggcta tgattgtgat tgaaggtagc gataaattta
     1141 agattgcaaa agaatatatt gatgtagaat atactctttt tagcaaagta acttttaggt
     1201 atgaaaagtt gaaatttaaa gataatgctg aattggaaaa aattaagatg tttaaatata
     1261 aaaatggcta catccctaat aaattaaacc tttcttttgg atatggattc tcttcttata
     1321 aaaagcaaat aattagagaa actgtagata ctttaagatt gacagaaatt ttttcaagcg
     1381 agaacataga agatattaaa tttataaaag atggtacaaa aaaattagaa attagcatag
     1441 agaaagttgt gaaatttaaa cgtcgaaaaa aaagaaatta tgtttgttgc tattgccctg
     1501 atatgtatag agacataaaa ctcgacaaag aatctatcaa taagatatac aacagaaaaa
     1561 taaaaataga aagagaagtt aatatttttg aagatgagga tgttataata aacaagaaag
     1621 tattgaagtt tccaaagtct tggacaaaga atatgcaaaa atattggtta agtgaaaata
     1681 agtatcccat acattctact gtaattgatg atgatagata taaatgttgt aatgtacaat
     1741 atacaaaaaa tagagtgata atattatatt acatatataa ccattaatat acataattac
     1801 aaaaaaataa tgacaaatat acataataca aatatatctt ctactttaga taaaacagtt
     1861 attatgaaaa cttactatct ataaataata gaaatgctag tataccatct ataatctaat
     1921 gtctagtagg ttttaatggc atattttaaa tatgccatag ttgatttata agattttcta
     1981 tatcactttc aaaatacaca ctaaatagtt gcttttcaga tataattgcc caatttaaat
     2041 tttactatct gaaaagtttt ttatatttaa tttatatctt caaaaatacc gtctaatatt
     2101 tctatataat taatttaatt aatactctta tgtaatagat taagtactga atttaactct
     2161 ttaaatgata tttgccctgg tgctgaaaca ctttttgcag ctccaaaagt caatgcagaa
     2221 ccaaatattt caccacacaa tctacttata acacccattc ctgacattga cattgttatt
     2281 attggtctat ctgcataaat tttaaacatt tcatttgtag cttcaagtag cactaacaca
     2341 tctttttcat tttgcggcat aacagctatt ttgggtaaat ctgcgcccaa ttcctgcatt
     2401 ctacataaac gagatacaat ctcttctttt tttggagttt tattaaaatc atgattagat
     2461 ataattactt tcacttcttt tttatgagca aaattaacta cttcatctat gacctcatct
     2521 cccataaata actctacatc tattaaatct actaaacctg tattagaaat ttctttattc
     2581 aaagtagtat aataatctct tgatattaat ttttctcccc cttctactac acttctaaat
     2641 gtgaataata aagggatatc atgtatataa cttcttaatt catagagaac ttccttaact
     2701 tctttaatat tttctacatt ctcaaaaaaa tcaactcgcc actctataat atccaaacat
     2761 gcatctttta actctttagc ctcttttata atatcttttt tatttttccc aataattggt
     2821 acacaaattt taggtctacc ttctccaata gtaatatttt ttacttgaac ttttcttttc
     2881 atattctcct ccataatcag aaattctata ggactttaaa ttctattttc tgcacaattt
     2941 aattatacat taaaaatact atacattata aaaatactaa tttaaaaata atttttattc
     3001 taattcttaa aacaatccca catattttag aaaaggtact ctataatata caaacacttc
     3061 ttttttacct aaatttattt taacatccta taattttcat aatattcttt aaattttatt
     3121 catataaaca atattattct ggatgctaat agaattaatc tataaatcat agtataatta
     3181 tgcagaaata actcgaattt cactacttat gaagagattg aatattaatg aatctaaatc
     3241 atttgcatta tttaagagtt ttgactaaag ttgaacacca tacaaaagta gctactcaat
     3301 tgtttatacc ccaaccaagc ttaagtaatg ttatatagat tctcgaaaaa gaatttagta
     3361 tctttttatt tgaaaaactt atattaaatt tgattatctt ttcataagtt ggtaaatgtc
     3421 gatatatcct gtatctacaa ggagtatcga cattttcttt ttggaagata ctttgcataa
     3481 gttggcattt aaccgtataa gaatgccatc aaaagtagta aataagtagt aaactctagt
     3541 catactacta ggcttataac cgttccattt cagctctcgc agaactaaat gaaccatgtg
     3601 cataatagcc aagcgtcata gtaatgtttt tatgccccat aatatattgc aatatattag
     3661 gactcattcc tttgttagcc atatttgtac agagtgtatg cataaagata tatggcgtaa
     3721 tctttggtag cttgtcctca tgggtcttgt tatacttctt gactaacgct cttaacatgc
     3781 tttgataatg agttgcttgt tttggtaatc catcttgttt aagaaatagg aagttctggt
     3841 aaccatcaac aatgattggt tctgctttag cgttcttacg ccgttcaacg atacgttcaa
     3901 atgattgata agctctttca gtcattggaa tttctcgctt accctgtgtg gtctttggaa
     3961 cttctacata atagccaatc ttagtatcac tcaacaattg atggtctacc ataatggctt
     4021 tatttttcat atccaattct aaagtcaaac cgcataattc agaaatgcgt agtcctgttt
     4081 ctaagaggat aacaacatca tcataatatt tacaataagt cttatcgctc tccataaagg
     4141 ataataagcc catttcctgt tctggtgtta gagcgatttt tggttctgtt gtatcttcca
     4201 aaacatcact taactgaaaa ttaaatggat tctttctaat acagtcgtct tgaattgcca
     4261 tgaaaaacga cgctttcagt gagcgcttat aattgccaat ggatttataa gcacacccat
     4321 cttcactcat tcggatagcc cagcttttag cgtctgataa tttaaccata tcaatgcttt
     4381 ttgcacctag tgggtcattg atagtatcta tattttgatt tataatttat acattttttt
     4441 aaaaacagac ttttaactgt aaagaatcta tgtataaact tagctatgtt gtccgtgtat
     4501 ctacaaagga tcttgacgag ctaaaaaggc attgtgatga agtcaaagac ttttacgacg
     4561 acttatcaat caagctcgtg catccctttg gggatatgtt gggattgcat ggcgaattta
     4621 ttcctgtcag caaacgttac atcaatgatt atattcaata tgtcacttcg gattttttgg
     4681 ctggacttgg ttttggagcg acacaaaccc ttggcgaaca tgaggatatc tatgttagct
     4741 acaatctgga cactggaaag aatgtctatc taaaacctgc ccttgctagt caaggggtaa
     4801 agggttctat taccaatgcg ttagcgtctg cgtttatcgg ttcattgggt ggtggtaaat
     4861 tattcagtaa caatatgctt gtttactatg cggtactatt cggcggatag gcggtcatag
     4921 ttgaccctaa agcaaaacgc ggcaaatgga aagaaacgct accagaaata gcccatgaga
     4981 taaacattgt caatttaacc agtgatgatg aaaacaaagg attgcttgac cattacgtca
     5041 ttttgagccg taaaaaggat tctgaaagtt tagcgattga tatcctaaca tttcttactg
     5101 gtatctccag tcgtgacagt gataagtttt tgcagaaaaa tgacaactgg aaaataataa
     5161 tggaatagtt tctatgtaaa tatattttta ctatcttacc taactaattg aaagatgata
     5221 taatttaatc aaagatttgg taaggaggga tgaatatgca tttaattgat tttatgaatg
     5281 aagatattaa aaagaagctt gttaaaaaaa cgtataaaaa gaaagagact attctttttg
     5341 ctgagcaaga aaatgaatat gtaattctta tgattgacgg tattgcagaa gcattcatct
     5401 taaatgtgaa aggaaacatc tcaacgattc atctttatag aagtggtagt ttttttggag
     5461 aaatggaaca atttaatgat gggaaaaaac ccgttgaaat tgtcgctttc acagattgta
     5521 atgtatataa acttcataga gatgattttt taaactggtt aaggggagat tttgaagcta
     5581 caaaatttct gattcgagaa atatctagta aattagttgt aaatgctgaa ttaattgaag
     5641 aattatcatc tttaagtgtt aaagaacgac ttctgaggtg tatatcctta cactattata
     5701 gaagtgaatt aaatctgctt accaaaaaac agcttgctag cgaagtaaac gctccaatta
     5761 gaagcattaa tcgtgctata aatgaatgtg tacaagaaca tctaattgct tatgaaaaca
     5821 aaagatttag tgtaattaat cagcgagagg tattaaagaa tcttcctaca acataagtat
     5881 aatttcaaaa aagtattgaa taataattat tcaatgcttt tttatttcgg gtcaagtgac
     5941 ctattttttt ttatttcttc attatataat actcctatgc ataattatgt tggattgata
     6001 gctaataaaa gacagtgaga ggtgttatat tatgactaaa acacaacaga aaatgataca
     6061 aaacgtatta gaattttcaa aaagagatag taggataata ggacttgcaa ttagcggttc
     6121 ttatatcaca aaatcgttag atgaatattc tgatttggat tttctgattg tagcagatga
     6181 taaatcctat gaagaagtta tcgaagagag attacttatt gtggaacagt ttggaacatt
     6241 agtttctgct tttactggcg aacatgttgg agaacctcga ttgataattt ccctctatga
     6301 ttcccctgtt cttcatgttg attttaagtt tacaacctta gatggtttac tagatagggt
     6361 tgaagattca gctattctct atgaagaaaa caactgcata acagaaattt attctaaaaa
     6421 agaagcatac ttcccaactc cagacttaca gtggattgaa gatagatttt ggatttgggt
     6481 tcattacgct tgcactaaga ttggacgtag agaactattt gaaacaattg attttttatc
     6541 ttttttaaga caatcagtac ttgccccatt aatacaactt ctcttaggta aattacctcg
     6601 tggagttaga aaaattgaat tggacgcacc ccaatatatt gaagcattag aaaagacggt
     6661 tgctaaccat gaatataaaa gctgtgttaa tgcattgcag gctactatca acctgtatct
     6721 tgagttaaga gaggaattat cacaaagtcc tattgtccga aaggttgaag ctgaaagggt
     6781 tgcattacag tattttcaag atttaatcaa ataaacccaa agtaaaaaaa tattgaatag
     6841 taaatattca gtgttttttc atttttggtc aaatgaccta gattagttgt tgtaacaatt
     6901 ctataattat tttgaaagta acagtatgga ggataactat gagtgatatt ttaagtagaa
     6961 ttacaaataa aattggggat aagaatatag ttgataagtt atcagctcta tcaaaatcag
     7021 atttgaactc acttctatta gaagtgtttg atagacaagc aaatacttta actgcaactg
     7081 atattctaaa gtcataccaa ctaaatagat ttactatccc tagcggtata gatccagaag
     7141 aaattcatgc tttggaatca aatttattga gaaaagcatt caatatggat atcaagacga
     7201 ttatgctttc tccctctgcc ccattaggta gctgtagcgt ttttggctcc gtagatcaat
     7261 ataacgtagt aagtgctcta cgagggacag aaacacttgc agacccctca aatatgttgg
     7321 caataattat tgctgataaa ttaaaaagaa aagaagaaaa taataccata cctatccaca
     7381 tggctactac tgctagggta ataagagcac aaaattttgt aggtaaaggt ttatattcac
     7441 attttggctt atattgtatg gtttcatctg gtatagatac agggtcttac acttgtgaaa
     7501 aaatgttgtt agaaaagcac ttaaactatt ataaagatat attaagtgaa atagaaaatg
     7561 ttcgtttctc tattattcta cgcaaaagaa acggatacaa agataatgac ggatttttcg
     7621 acagaatggt tgaaactatc aaacttattt ttcctaatat agagttatca attcataatg
     7681 atgatgttga taataattat tataaaggta tcaatttcaa aatatcggtc aaacaaggaa
     7741 atgaaaccgt tgaaatagct gacggtggat ttgttgactg gacttatcaa atgcttggaa
     7801 ataaaaaaga acgctgtttg ataagtggta ttggcttaga aagatttctt gtagctgttt
     7861 cataaaagga gaagaaaaat ggaacttata gagtggaatt atgcttatat taccgagtta
     7921 gttgagtttg cgaatgataa agaaattgca aacaatcttc gtgacaactt cccccaccct
     7981 tatagggagc aaaacgctag agattttatt agtttttgtt tggcaactcc agatgttaaa
     8041 caacttagct atgctatttt ttatcaagaa agggctattg gaagtatcag cctaacattt
     8101 gaagaagata cctctattaa taaaaatgct gaattaggtt actggcttgc taggaactat
     8161 tggggcaaag ggatagcaac aaatgcaata aaagaaatat gcaaaattgc ctttgaaaaa
     8221 tacaacctta acaaaattca tgctaatgta tattcctaca atagagggtc aagtaaagta
     8281 ttggaaaaat gtggttttaa gattgaagaa tactgtcaca attcataata aagaatagaa
     8341 acatgattga ttgccatgta tatagtttaa ttcgaccgca atagcattta ttagaattaa
     8401 cctacttttt aataacagaa taagtttttc ccctctatta atttcttatg catctttgta
     8461 tttttatgaa aagctagcca atgcatattt ccatacatca atatggtggt ggcttacaac
     8521 caatataaat taaatacgtt ttaaagaata cacatttttg ccctataggc agagtgtgta
     8581 tttttttctc ttttttttga aatttatcga agatttaatt ccctcccacc gtgataggag
     8641 taagcaaggt tatttaactc cttgcgatgg aaagagggtg aaatcttatg gttgatgaaa
     8701 agacaattga acatcaattc gacagtttct gtaaaacagt tttgcgtaac tatgctagag
     8761 atatttatga cgaaaataaa cgcagaaatg attatttggt atctctcgaa tctttgtcac
     8821 ttgcagaatt aagtaaattg agtattttag atgattatga ttctaactac atctgtatgg
     8881 tttcttacga ctacaacata cgaattgaag atgtattaat ggcacaagca atcggaaaac
     8941 ttacaaaaag aaaacaagat ataattctac tttcattctt tctcaacatg acaaatgctg
     9001 acatagcaac attgatggat ttagcagaaa ataccataca ttatcacaaa acaaatgcac
     9061 taaaagagtt gaaagaactc atggaggaac atgaaatgaa acctactaaa gaagtattac
     9121 cttttacaat tattttactt gctgtacatg gcgatgtaaa tgcaataaac ggaatactta
     9181 aacattttga acactatatc attcgtcttt cacagaaaac tttatttgat gaatacggaa
     9241 atccctatat tcatgtagaa gaagaaacaa agcgaatgct aggaacaaaa ctaatcactg
     9301 ctattttgag atttaatttg tcttaatctc gccctctctc catgtatcaa gctatttggt
     9361 acatggagaa tcactaatta tttgtctata aaagcccaca agctattgtg attttttata
     9421 ggcaaatcaa tgccgactgt tctttgacaa ctgaataaag tagatagata cgtttgtgat
     9481 acagatagcc aacaaatact atacgccatg accttaatca agagagctac tatatagtga
     9541 tttgtgaata acctttggaa cggttgtttt gccgtaacct gtaccacagt ataatgatac
     9601 acctgtatga cacggttctg cccataagaa tgggattggt tgaaatacca atggagctta
     9661 ccaaagccat ctatctactt ctgaactacg aacatagaaa ggagtgatac attctatgaa
     9721 caatactgat gtacctattt gggaaaaata taccttgacg attgaagaag cgtcaaaata
     9781 ctttcgtatt ggagagaaaa aattacgtaa acttgctgat gaaaaccttg attctggctg
     9841 ggtcattatg aatagcaatc gcattcaaat aaagagaaaa caatttgaga aaatcgttga
     9901 tacacttgac gttatctaat gaaattgagc cttatatgtt ataatattca tatgacgtat
     9961 caagctcaat tcggttattg agaggagctt cttatcatgt caactgaaaa aagacgagat
    10021 aataaagata gaattttaag aactggagag agccagagaa aagatggaag atacgcatat
    10081 aagtatgtat attcatttgg taaaccacaa tttgtttact cttggaaact tgtacctact
    10141 gataaacccc caaagggaaa acgtgatgat atatcattaa gggataagga aaaagcaata
    10201 caaaatgacc ttgatgatag cattgacact attggtaaga aaatgacagt ttgtcagtta
    10261 tacgctaaaa agaatgtact aagaaagaat atccgactta acactaaaaa aggacgccat
    10321 tatcttatga agattcttaa caaggagtga ttctgtgaag agatgtattg tagtagtgga
    10381 atagtcaaaa acataatata tattaaagga gagatttaaa tatgactatt ccaagttcaa
    10441 ataaggtata tccaagaagt aatgattatc aaactgtata tcttaaaaat gtaataacaa
    10501 gggaaaatat agaagttgga gattacacaa tatataatga cttttataat gacccaagag
    10561 attttgagaa aaacaatgta ttgtatcatt accctataaa caatgataaa ttaataattg
    10621 gtaagttttg ctcaatagca tgtaatgcaa aatttctaat gactagtgga aatcactcaa
    10681 tgaaatcaaa atccacatat acttttccca tcttttatga agaatggaaa ctcgatatca
    10741 accatataac ggacgcttgg gacaataagg gtaacattat aattggaaat gatgtgtgga
    10801 taggttatga ttctataatt atgtcaggtg taaatattgg tgatggtgca attattggaa
    10861 caagagcagt agttactaat gacgtcccac cgtattctat tgttggagga gtacctgcaa
    10921 aaattataaa aaagagattt aataatgata caatttcaaa attattagaa attaaatggt
    10981 gggattggcc atataaaaaa attcaatcaa acattaagca tattcaatca ggaaatattg
    11041 ataaattagt ttaatatttt ataatttatt tatattaaac tttactttaa taatcatttt
    11101 ataagagctt tttcaaaatt tgtatattat tttaatatat ataaatttaa tacaacatta
    11161 aat
//
LOCUS       DAMJXI010000214         9906 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.guided.109, whole genome shotgun sequence.
ACCESSION   DAMJXI010000214 DAMJXI010000000
VERSION     DAMJXI010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9906
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.guided.109"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            235..636
                     /locus_tag="PC465_004009"
     CDS             235..636
                     /locus_tag="PC465_004009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004079988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2651211.1"
                     /translation="MKFNEKLMSIRKAKGLSQEELGMELQVSRQTISKWESGQSYPDF
                     QRLVMLSDYFDMTLDELVKDIDVQDVRDKNLTDEKVASIYLDVENVKNKSRKFVKIFC
                     YAGVILLGIVILAFILHLFFPDIEWLWGSTQ"
     gene            797..1216
                     /locus_tag="PC465_004010"
     CDS             797..1216
                     /locus_tag="PC465_004010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016281639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2651212.1"
                     /translation="MTEEEAYKVHIQYTFNAFCKVVIRHAAIDIILKLRRRWEREVSL
                     DYLMNEKFVQLAEPEQLEEYLFTACGQTAVLYHAELAAALALLPEQTQEEIFRYYFLR
                     QPQRVIGAHIGRSRSTAGRHIQLALQRLREEMEVRRP"
     gene            1213..1410
                     /locus_tag="PC465_004011"
     CDS             1213..1410
                     /locus_tag="PC465_004011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002571019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2651213.1"
                     /translation="MSKLLPYETIVKAHEGDPEAVDAVLAHYSRYIRYFSKINGQGNA
                     EVEDYVKQRLIASQFKFRFDR"
     gene            1510..1842
                     /locus_tag="PC465_004012"
     CDS             1510..1842
                     /locus_tag="PC465_004012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009215075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2651214.1"
                     /translation="MARKYDHEYKVQAVKLAKEIGGAKAAKELGIPEGTIHTWLKAVR
                     AGKLDIGEGSHTPTSAMSLAEEITMLRKRVKEQDKEIRRLKEENEFLEEASAFFAASR
                     RKSAKTRE"
     gene            1839..2747
                     /locus_tag="PC465_004013"
                     /pseudo
     CDS             1839..2747
                     /locus_tag="PC465_004013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009248860.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            2864..3298
                     /locus_tag="PC465_004014"
     CDS             2864..3298
                     /locus_tag="PC465_004014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002605002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2651215.1"
                     /translation="MIKKAETNDLEILAKLAVMMWQNHSVSELINEFSEIMANGKSQF
                     FLKYENDIPIGFAQCQLRYDYVEGTSTSPVGYLEGIFVQEGYRNKGYAKELLAKCEAW
                     AKENGCHEFASDCEIDNMNSFHFHKAMNFTEANRIICFTKTL"
     gene            3810..4208
                     /gene="mobC"
                     /locus_tag="PC465_004015"
     CDS             3810..4208
                     /gene="mobC"
                     /locus_tag="PC465_004015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HDF2651216.1"
                     /translation="MPKRYNTPHRSRVVKTRLSEDEYADFTARLAPYGISQSEFLRQA
                     IRRTAIRPIIHVSAVNDELLSAVGKLTAEYGKIGGNLNQIARYLNEYGAPYNALSGEV
                     RAAIADLAALKYEVLQKVGDAVGNTQAYQL"
     gene            4180..5796
                     /locus_tag="PC465_004016"
     CDS             4180..5796
                     /locus_tag="PC465_004016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDF2651217.1"
                     /translation="MATLKHINSKNADYGAAEQYLLFEHDEFTMKPVLDETGRLIPRE
                     DYRLSTLNCGGEDFAVACMRANLRYEKNQRREDVKSHHYIISFDPRDGPDNGLTVDRA
                     QELGEKFCAEHFPGHQALVCTHPDGHNHSGNIHVHIVINSLRIEEVPFLPYMDRPADT
                     KAGCKHRCTDAALRYFKSEVMEMCHREGLYQIDLLNGSKNRVTDREYWAQKKGQAALD
                     KQNAPMIAGGITPRQTKFETNKEKLRQTIRAALSAATSFEDFSSLLLREGVAVKESRG
                     RLSYLTPDRTKPITARKLGDDFDRAAVLAVLEQNAARAAEKAAAIPEYQRHGKTGIQP
                     TKAPQTAPNVQRLVDIEQKKAEGKGRGYERWATMHNLKQMAATLNVYQEYGFTSPEQL
                     EAAVDTAYQDMRQTSGELKALETKLQGKKELQQQVLAYAKTKPARDGLKAQKSEKARA
                     AYRQANESDFIIAEAAARYFKAHGITKLPARKALQAEIEQLVSKKSGLYNTYHEQKQR
                     YTELQTVKRNIDQILRREEPRRRKEQSHER"
     gene            5786..6172
                     /locus_tag="PC465_004017"
     CDS             5786..6172
                     /locus_tag="PC465_004017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009259636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HDF2651218.1"
                     /translation="MSDKLPRMDYRQHRRARRLVHECCNYDEGNCLLLDDGEPCVCVQ
                     SISLSLMCRWFRVAVLPLDGELAAALLYRGSRKRCAVCGAAFVPKSNRGKYCPDCAGR
                     MKKIKAAERKRKQRHKCHALEPFKPA"
     gene            6245..7039
                     /locus_tag="PC465_004018"
     CDS             6245..7039
                     /locus_tag="PC465_004018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006356266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HDF2651219.1"
                     /translation="MRDKLPKSTRTQGGDTIADYIMADTPLPLFLPYPRFLLKMEISQ
                     TAKLLYSLLLDRSTLSQKNKWQDDKGRIYIIYPIAEIAEILDKGSTTIKGALNELDAA
                     GLLERERGGFSAPNRLYVKVPRVPQVQFSDQLMAGNPTLTEPENRPTDGQKTDLMMVG
                     KPSPNQTTINNLTENQTKGVSGEPPAPYGRYQNIFLSQTEYNELQAEYPDRLERFIEE
                     MSRYLAASGKSYQNYAAALRIWAGNDKKGAPKKGIPDYSCKEGESL"
     gene            7036..7878
                     /locus_tag="PC465_004019"
     CDS             7036..7878
                     /locus_tag="PC465_004019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015518395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2651220.1"
                     /translation="MKNEINAVLENMTATTPEPEDYTGEDGLLYCGKCRKPKEAYFAP
                     DKAAIFGRDRHPAECDCQRAAREEREAAEKRRRHLDTVEELKRRGFTDPTMRDWTFEN
                     DNGRNPQAGIARRYVEHWEDMRTDNIGCLFWGGVGTGKSYLAGCIANALMEKEIPVHM
                     TNFALILNDLAASFEGRNEYISRLCRYPLLILDDFGMERGTEYGLEQVFNVIDSRYRS
                     GKPLIVTTNLTLDDLRNPEDTAHSRIYDRLLSMCVPVRFTGENFRQETAQRKMESMKK
                     LITD"
     gene            7893..8081
                     /locus_tag="PC465_004020"
     CDS             7893..8081
                     /locus_tag="PC465_004020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002571011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-encoded TnpW family protein"
                     /protein_id="HDF2651221.1"
                     /translation="MADNKQHDTRTARRPDCVTEIRMGNSVLVVSGYFKKDTTTTAAD
                     KMARVLEAEAAATQKPAI"
     gene            8193..9812
                     /locus_tag="PC465_004021"
     CDS             8193..9812
                     /locus_tag="PC465_004021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2651222.1"
                     /translation="MLRQATQNLITALYPRLSHEDELQGESNSISNQKRILETFAKQN
                     GFANLRWYTDDGYSGANFQRPGFQAMLADIEAGKVGTVIVKDMSRLGRNYLQVGFYTE
                     MLFPQKGVRFIAVNDNVDSANGGMDNDFTPLRNLFNEWLVRDTSKKIKAVKRAKGMSG
                     KPVTSKPVYGYLMDEDENYIVDEETAPVVKQIYQLCLAGNGPTKIARMLTEQQIPTPG
                     TLEYRRTGSTRRYHPGYECKWATNTVVHILENREYTGCLVNFKTEKPSYKTKHSIENP
                     IEKQAIFPNHHEPIIDTETWERVQELRKQRKRPNRYDEVGLFSGMLFCADCGHVMYQQ
                     RYQNKTRKQDCYICGSYKKRTRDCTAHFIRTDLLTAGVLSNLRQVTEYAAKHESRFVK
                     LLIQQNEIGGKRKTAVATKQLEQAQERISEVSRIIKRLYEDNVNGKISDERFMELSAD
                     YEQEQRELKDRAAALQEELDKSQAATVNAEKFMGIVRKHLAFEELTPTLLREMIEKIV
                     VHECSYDENGTRRQDIEIYYSFVGKIDLPET"
BASE COUNT         2746 a         2554 c         2599 g         2007 t
ORIGIN      
        1 aatgctcatg tgccataaag taacacacaa gaatttgata gacagcagcc cattattcca
       61 aatatatgtg tcaacaaata gctacactca tgttttgaaa ggtttaccta tgctttcaaa
      121 acgcttgaat ttcaagatgt tacagcgaat tgacaaattg ccaacacttc ttgcttgcca
      181 gtaaaacccg aaaactatat acttgataca acaaacgcaa ggaggatttt gcaagtgaag
      241 tttaatgaga aacttatgtc cattagaaaa gcgaaaggct tatcgcaaga ggaattggga
      301 atggaacttc aggtttcaag gcaaaccatt tctaaatggg aatctggaca atcttacccg
      361 gattttcaaa gattagttat gttgagtgac tactttgata tgactttgga tgagttggta
      421 aaagacattg atgttcaaga tgtgcgcgat aaaaatttaa ctgatgagaa agtggcatct
      481 atttatttag atgtcgaaaa tgtaaaaaac aagtccagaa aatttgtaaa aatcttttgt
      541 tatgctggtg tcatattgtt gggaatagtt attttggcct tcattctaca tttgtttttc
      601 cccgacatag aatggctttg gggaagtact caataacgaa tcatttagca aagccagccg
      661 agccagtcaa cggtcaagat aaacggcgca tacgcgccgc cgttgacagc cccgcccgcc
      721 tttgctgata ggcaatcaag gggcgacagc aaggagtgct gccgccccgc actattatca
      781 gagaggggga atttccatga ccgaagaaga agcctacaaa gtgcatatcc agtacacctt
      841 taacgccttt tgcaaggttg tcattcgtca cgccgccata gatataatct tgaagctgcg
      901 ccggaggtgg gaacgggaag tttcccttga ctatctgatg aatgagaagt ttgtccagct
      961 tgccgagccg gagcagcttg aagaatatct ttttactgcc tgcggccaga ccgctgttct
     1021 gtaccatgcg gaacttgctg ccgcccttgc cctcttgccg gagcagacgc aggaagaaat
     1081 tttccgttac tatttcctgc gccagccgca gcgagtgatc ggcgcgcaca ttggccggtc
     1141 acgcagcaca gcggggcggc atatccagct tgccttgcag cggctccggg aagaaatgga
     1201 ggtgcggcga ccatgagtaa acttctcccc tatgaaacaa tcgtcaaggc acatgagggc
     1261 gaccccgagg cggtggacgc tgttctcgct cactactcca gatatatccg ctacttttcc
     1321 aagataaacg gacagggcaa tgccgaggtg gaggactatg tgaagcagcg gctcattgcc
     1381 agtcaattca aatttcggtt tgaccgatag ctggcataga aaaattcata gtggtgtggt
     1441 ataaaaaaag ttgacagctt attctcaagg atttcataat aaaaccaaga gaataaggag
     1501 gcattcaaag tggcacgtaa atatgaccat gaatacaaag tacaggcagt aaaacttgcc
     1561 aaggaaatcg gcggcgctaa ggctgctaaa gaattaggaa tcccagaagg aaccatccat
     1621 acctggctga aagctgttag agccggtaag ctggatatcg gagaaggctc ccatactccc
     1681 accagcgcaa tgagcctggc agaagaaatt accatgctgc gcaaacgggt aaaggaacag
     1741 gataaggaaa tccgtcgcct gaaggaagaa aacgaattcc tggaggaagc cagtgctttt
     1801 ttcgccgcca gccgtcggaa gtcggcaaaa accagagaat gatctttctg gccctgaaga
     1861 cagaagacgg caggattacc gggaaaatct agttttactg cagaatgctt ggggtcagcc
     1921 gccaaggctt ctataaatat ctcgcaaata aagaccgtcc ctggaagtac caggatttgg
     1981 cagatgccat gaaagaaatc gtcagtgaag atgaatgtaa cgatacttat ggtcgaatcc
     2041 ggatgtacca ggcattgttg ctgaaacagc cggaaggagt gcatattccc agtgagagaa
     2101 ccgtataccg agttatggat cagattggcc ttagccatcg acctaagaga aaacccaacg
     2161 ggatcacaaa ggctgatcgt gaagccatga aatcggatga tctgctaaaa cgggatttcc
     2221 gttctgatac cccattagaa aaatgtatta cggatatcac ggagattccg gcatccaatg
     2281 ggaaactgta tgtatctgcg atttttgact gctttgatct tagtgtcctc ggtctggcaa
     2341 tggaaacaaa tatgaaagcc gatctatgta tccatacatt ggaaaacgcc ctgactgcct
     2401 atcctgcgtt ggaaggcgct atcatccaca gtgaccgtgg gacacagtat accagcgagt
     2461 cctaccgtca gaccatccgg gagcatcata tccatcaaag catgaacagt gccggagggc
     2521 gctgccatga taatgcacgc tgcgagagca tgtgggccag aatgaagacg gagcttcttt
     2581 atgaccgtta tgacacaaag cagatggaag tagaagaact aaaggtactt atctggagat
     2641 actttctcag ctactggaac aaccggagga tctgctctgc caatggcggc cttcctccca
     2701 tggtaaaacg caggcagtac tatgaggctt tggaggtggc tgcatagtca gtgatatcct
     2761 tgagaaaaat gtgtcaacta atcttgacaa tatcatagct gcatggtaga atgaagttat
     2821 caaatgaaac aataaagtga aatttgcaaa ggagagcgta tgtatgataa aaaaggcgga
     2881 aactaacgat ttagaaatac ttgcaaaatt agctgtgatg atgtggcaga accattccgt
     2941 tagtgaacta atcaatgaat tttcagaaat tatggccaat ggaaaatcac aatttttttt
     3001 gaaatatgaa aatgacatac ctattggttt tgcgcaatgt caattaagat atgattatgt
     3061 ggaaggtaca agtacctctc cggttggata tttagagggg atttttgtgc aagaaggtta
     3121 tcgcaataaa ggatatgcca aagaattgtt agccaagtgc gaagcatggg cgaaagaaaa
     3181 cggttgccat gagtttgcca gcgattgtga aatagataat atgaatagtt tccattttca
     3241 taaggctatg aattttacag aagcaaatag aattatctgt tttactaaga cactataaag
     3301 cccagttcat ctgactgatt tcccattgaa aaccaaatac ccgccgcccc gcaacggcac
     3361 aacgagcagt aagtcttgaa aaagatttac tgcttttttg cgcccatttt tgtcaaaacg
     3421 ggaacggcgg tggtatttag agtgaacggg gaaatatacc ctttttctct tgccggaacg
     3481 gtaggaaaaa gaaatcttcc gttttccccc gtacagcggg cagcaaagcc cttttcaagc
     3541 gttatattag cggaaaagaa gaaagcccgt atacgccgga gattgcagct acaaagagca
     3601 agtttctacc acggtgccaa aatccgcaat tctgcggttt tgcccctcgc gggaaacttg
     3661 ttggggagtg ccttccccaa accctgctat ggcggcttgc gccgcaaaaa tatttccgtc
     3721 cggcaggccg cttttttgcg agaactgccc cggaaatacc taacagacca gcctattttt
     3781 tgtgataagt gaaaggaggt ttacagccca tgccgaagcg atacaacaca ccccaccgca
     3841 gccgcgttgt gaaaacccgg ctgtccgaag atgaatacgc cgacttcaca gcgcggcttg
     3901 cgccctatgg tatcagccag tccgaatttc tccggcaggc gatacggcgc accgccatac
     3961 gccccattat ccatgtgtca gcggtcaatg acgagctgct ttccgctgtc gggaaactca
     4021 cagccgagta cggcaaaatc ggcggcaacc tcaatcagat agcccggtat ctgaacgagt
     4081 acggcgcacc ctacaacgcg ctgtccggcg aggtacgcgc cgccatagcc gaccttgccg
     4141 ccctcaagta tgaagtctta cagaaagtag gtgacgcagt tggcaacact caagcatatc
     4201 aactctaaaa acgccgacta cggagccgcc gaacagtacc tgctgtttga gcatgacgag
     4261 tttaccatga agcccgtcct tgatgaaacc ggcaggctta tcccccgcga ggactaccgg
     4321 ctgtccacgc tgaactgcgg cggggaggat tttgccgttg cctgtatgcg ggcaaatctc
     4381 cgctatgaga agaaccagcg gcgggaagat gtgaaaagcc accactatat catcagcttt
     4441 gacccacggg acggcccgga caacggtttg accgtagacc gggcgcagga gttgggcgag
     4501 aagttttgcg ccgagcattt ccccggccac caggcccttg tatgcaccca cccggacggc
     4561 cataaccaca gcggcaatat ccatgtgcat atcgtcatta acagcctgcg gatagaggaa
     4621 gtcccgttcc tgccctacat ggacaggcca gccgatacga aagccggttg caagcaccgc
     4681 tgtaccgacg cggccttgcg ctacttcaag tccgaagtca tggagatgtg ccaccgggag
     4741 gggctttacc aaatcgacct cttgaacggc agcaagaacc gcgtcacaga ccgggagtat
     4801 tgggcgcaga aaaagggaca ggccgcgctg gacaagcaga acgcccccat gattgcaggc
     4861 ggtatcacgc cccggcagac caagtttgaa acgaacaagg agaagctgcg gcagaccata
     4921 cgcgccgcgc tgtctgcggc gacctcattc gaggactttt cctctctgct gctgcgggag
     4981 ggcgtggccg tcaaggagag ccgggggcgg cttagttacc tcacgccgga caggacaaag
     5041 cccattaccg cccgcaagct gggcgacgat tttgaccgcg ccgctgtcct tgccgttttg
     5101 gagcagaacg ccgccagagc cgcagaaaag gccgcagcca tacccgaata ccagcggcat
     5161 gggaaaaccg gcatacagcc cacaaaagcc cctcaaaccg cgccgaatgt gcaacggctt
     5221 gtggacattg agcagaagaa agccgagggc aaaggccggg gctatgaacg ctgggcgacc
     5281 atgcacaacc tcaaacaaat ggccgcgacg ctgaatgtgt atcaggaata cggcttcact
     5341 tccccggagc agttagaagc cgccgttgat accgcctatc aggatatgcg ccagaccagc
     5401 ggcgaactga aagcactgga aacgaagcta caagggaaaa aggagttgca gcaacaggta
     5461 cttgcttacg ccaagaccaa gcccgcccgc gacgggctga aagcgcagaa atccgagaaa
     5521 gcccgcgccg cataccggca ggcaaacgag agcgatttta tcatagccga agccgctgcc
     5581 cggtatttca aggcgcatgg cattaccaag ctgcccgccc ggaaagcgtt gcaggccgag
     5641 atcgagcagc ttgtttccaa gaaatccggc ctgtataaca cctaccacga acagaagcag
     5701 cggtacacgg agttacagac cgtcaagcgg aatatcgacc agattttgcg ccgggaggaa
     5761 ccccgccgca gaaaggagca gagccatgag cgataagctg ccccgcatgg actaccgcca
     5821 gcaccggcgg gcgcggcggc tggtgcatga gtgctgtaac tacgacgagg ggaactgcct
     5881 gctgttagac gacggggagc cttgcgtatg cgtccagagc atttcccttt ccctcatgtg
     5941 ccgctggttc cgtgtggctg tcctgcccct tgacggggaa ctggccgcag ccctcttgta
     6001 ccgggggagc cgaaaacgct gcgccgtctg cggggcggct tttgtcccca aatccaaccg
     6061 ggggaaatac tgccccgact gcgccggacg catgaagaaa atcaaggccg ccgagagaaa
     6121 gcggaaacaa aggcataaat gtcacgcttt agagcctttc aaacccgcat aaatcaaggc
     6181 ttttttcgtg ggtgtcaaag ggtgcgcgat acatttatcc ttttccaccg gaaacgccgt
     6241 cctaatgcgt gacaaactgc caaaatcaac ccgaacacag ggaggtgata ctatcgctga
     6301 ttatatcatg gcagacacgc cgctgcctct ctttctgcct tatccccgtt tcctgctgaa
     6361 aatggagatt tcccagaccg ccaagctgct gtattcgctt ctgttagacc gctcaaccct
     6421 ctcacagaaa aacaagtggc aggacgacaa gggcaggatt tatattatct atcccatcgc
     6481 ggagatagcc gaaatactgg ataaaggcag caccaccata aagggggcgc tgaatgaact
     6541 ggacgcggcg gggctgctgg aacgggaacg gggcggcttc tccgcaccga accgtctata
     6601 tgtcaaagta cctcgagtgc cacaagtaca gttttccgac caactgatgg ccggaaatcc
     6661 gaccctcaca gagccggaaa accgacctac tgatggtcag aaaaccgacc ttatgatggt
     6721 cggaaaaccg tcccctaacc aaactactat aaacaacctt acagagaacc aaacaaaggg
     6781 agtgagtggg gagccgcccg cgccctatgg ccgataccag aatatttttc tgtcacagac
     6841 cgaatacaac gagttgcagg cagagtaccc cgacaggctg gaacggttca tcgaggaaat
     6901 gagccgctac cttgccgcca gcgggaaaag ctaccagaat tatgccgccg ccctgcggat
     6961 atgggcgggg aacgacaaaa agggcgcccc gaaaaagggc atccctgact actcatgcaa
     7021 ggagggcgag agtttatgaa gaacgaaatc aacgctgttt tggagaatat gacggccacc
     7081 accccggagc cggaggacta caccggcgag gacggtttgc tgtactgcgg caagtgccgc
     7141 aaaccgaaag aagcctattt tgcgccggat aaggccgcta tctttggccg tgaccgccac
     7201 ccggcagagt gcgactgcca gagagccgcc cgcgaggaac gggaggccgc cgagaagcgg
     7261 cgcaggcacc ttgacaccgt ggaagaactg aaacgccggg gctttaccga ccccaccatg
     7321 cgggactgga cttttgagaa cgacaacggc aggaacccgc aggccgggat tgcccgccgg
     7381 tatgtggagc attgggagga tatgcgaacc gacaatatcg gctgcctgtt ctggggcggc
     7441 gtgggaaccg ggaaaagcta ccttgcaggc tgtatcgcaa acgccctcat ggagaaagaa
     7501 atccccgtcc acatgacgaa ctttgccctt atcctcaatg accttgccgc cagctttgag
     7561 ggcaggaacg aatacatttc ccgcctttgc cgctatccgc tgcttatcct tgacgacttc
     7621 ggcatggagc gcggcaccga gtatgggctg gaacaggttt tcaatgtgat tgacagccgt
     7681 taccgcagcg gcaagccgct gatcgtcacg accaacctca cgctggatga cctgcgaaac
     7741 ccggaggaca ccgcccattc ccggatttat gaccggctgc tttccatgtg cgtcccggta
     7801 cgctttactg gcgagaattt ccggcaggaa accgcgcagc ggaaaatgga gagcatgaag
     7861 aaactgatta ccgactgaaa ggagtattgc ctatggcaga taacaagcag cacgacaccc
     7921 gcaccgcccg ccgccccgac tgcgtgacgg aaatccgcat gggcaattcc gtccttgtcg
     7981 tgtccggcta tttcaagaaa gacaccacaa ccaccgccgc cgacaaaatg gcgcgggtac
     8041 tggaagcgga agccgctgct acacaaaaac cggcgatttg acaagctgta aagaagcaga
     8101 tttgacactt ttgccgctat acaaccagcc ctgttccgtg gtacaatgaa accacggaat
     8161 agtggggctg gctgtcggaa acggaggatt ttatgttaag acaagccacc caaaacctca
     8221 ttaccgccct ttatccgaga ttgtcccatg aggacgaatt gcaaggcgag agtaattcca
     8281 tatcgaacca aaaaaggata ctcgaaacct ttgcaaaaca aaatggcttt gccaaccttc
     8341 gctggtacac cgacgacggc tattccggcg cgaactttca aaggcccggt tttcaagcca
     8401 tgcttgcaga cattgaagcc gggaaagtgg gtacggtcat tgtcaaggac atgagccggt
     8461 tagggcgaaa ctacttgcag gtgggatttt acacggaaat gctgttcccc caaaagggcg
     8521 tgcgttttat cgctgtcaac gacaatgtgg acagcgcaaa cggcggcatg gacaacgatt
     8581 ttacccctct gcgaaatctg ttcaacgaat ggctggtgag agatacgagc aagaaaatca
     8641 aggcagttaa gagagcaaaa ggcatgagcg gcaagcccgt taccagcaag ccggtctatg
     8701 gctacctcat ggacgaggac gaaaactata tcgttgacga ggaaaccgcg ccggtagtca
     8761 agcagatata ccagctttgc cttgccggga acggcccgac caagattgcc cgtatgctta
     8821 cggagcagca aatccccacg ccggggacgc tggaataccg caggacgggc agcacccgcc
     8881 gctaccaccc cggctatgag tgcaagtggg cgacgaacac cgttgttcat atcctcgaaa
     8941 accgtgagta caccggctgt ctggtaaact tcaagacgga gaagccttct tacaagacca
     9001 agcacagtat agagaacccc atcgagaagc aggccatttt cccgaaccac catgagccga
     9061 ttatcgacac ggaaacatgg gagcgcgtgc aggagttacg caagcagcgc aaacgcccga
     9121 accgctacga tgaagtgggg ctgttctccg gtatgctgtt ctgcgccgac tgcggccatg
     9181 tgatgtacca gcagcggtat cagaacaaaa cccgcaagca ggactgttac atctgcggca
     9241 gctacaagaa gcgcacccgc gactgtacgg cgcactttat ccgcaccgac ctgttgaccg
     9301 ccggtgtcct ctccaatctc cggcaagtga cggaatacgc cgccaagcat gagagccgct
     9361 ttgtgaagct gcttatccag cagaacgaga tcggcggcaa aagaaagacc gccgtagcca
     9421 ccaagcagct tgaacaggcg caggagcgca tttccgaagt gagccgcatt atcaagcggc
     9481 tgtatgagga caatgtgaac ggcaaaatca gcgacgagcg tttcatggaa ctgtcggcag
     9541 actatgagca ggaacagcgg gaactgaaag accgcgccgc cgctttgcag gaggaactgg
     9601 acaagtcgca ggccgccacc gtcaacgcgg aaaagtttat gggtatcgtc cgaaagcacc
     9661 ttgcctttga ggaacttacc cccaccctct tgcgggaaat gattgagaaa atcgtcgtgc
     9721 atgagtgcag ctatgacgag aacggcaccc gcaggcagga cattgagatt tattacagct
     9781 ttgtcggcaa gattgacttg cccgaaacct aacgcccgac ctatccgaca caacgcgcga
     9841 gtgccggata ggaacggcaa aattttttac acttctatta cttctttatc gcacatcagt
     9901 aaaatc
//
LOCUS       DAMJXI010000215         5213 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.guided.146, whole genome shotgun sequence.
ACCESSION   DAMJXI010000215 DAMJXI010000000
VERSION     DAMJXI010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5213
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.guided.146"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            24..416
                     /locus_tag="PC465_004022"
     CDS             24..416
                     /locus_tag="PC465_004022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2651223.1"
                     /translation="MKLLFIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            417..1856
                     /locus_tag="PC465_004023"
     CDS             417..1856
                     /locus_tag="PC465_004023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HDF2651224.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
     gene            complement(1986..3158)
                     /locus_tag="PC465_004024"
     CDS             complement(1986..3158)
                     /locus_tag="PC465_004024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HDF2651225.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
     gene            3716..4027
                     /locus_tag="PC465_004025"
     CDS             3716..4027
                     /locus_tag="PC465_004025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF2651226.1"
                     /translation="MIRNPYLPLTETTFYILLVLTAPAHGYAIIQEIDKLSEGSVKVA
                     AGTMYGAIENLLKLNWIEEIPSREKRRRVYKITDLGEEVLRLEIDRLGSLIKLSSDFG
                     Y"
     gene            4458..4988
                     /locus_tag="PC465_004026"
     CDS             4458..4988
                     /locus_tag="PC465_004026"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651227.1"
                     /translation="MEKILENTLLLMILPWIFVWGILCILEKRKRKNEDGNKDEKSYV
                     IQNDNMFFPFFSLGMFLFSFCLFYTVFFTEFDISEVISVSVFVIFFAILTLDSAIWRV
                     IVDGDIIKYRSFYGITRTYNFNDITKGVYTKKGSLKIYIEGKRIFTFYDNLEFSLFEN
                     QMRKRKIPLEYKRKEK"
BASE COUNT         1873 a          621 c          934 g         1785 t
ORIGIN      
        1 tatagttgaa gaatattatc ctattgaaac tattgtttat tgatgataat atggtttttg
       61 atattgataa tttaaaagga tttcttaatg ataccagttc atttgggttt atagctaaag
      121 aaaataataa aattatagga tttgcatatt gctatacact tttaagacct gatggaaaaa
      181 caatgtttta tttacactca ataggaatgt tacctaacta tcaagacaaa ggttatggtt
      241 caaaattatt atcttttatt aaggaatatt ctaaagagat tggttgttct gaaatgtttt
      301 taataactga taaaggtaat cctagagctt gccatgtata tgaaaaatta ggtggtaaaa
      361 atgattataa agatgaaata gtatatgtat atgattatga aaaaggtgat aaataaatga
      421 atatagttga aaatgaaata tgtataagaa ctttaataga tgatgatttt cctttgatgt
      481 taaaatggtt aactgatgaa agagtattag aattttatga tggtagagat aaaaaatata
      541 cattagaatc attaaaaaaa cattatacag agccttggga agatgaagtt tttagagtaa
      601 ttattgaata taacaatgtt cctattggat atggacaaat atataaaatg tatgatgagt
      661 tatatactga ttatcattat ccaaaaactg atgagatagt ctatggtatg gatcaattta
      721 taggagagcc aaattattgg agtaaaggaa ttggtacaag atatattaaa ttgatttttg
      781 aatttttgaa aaaagaaaga aatgctaatg cagttatttt agaccctcat aaaaataatc
      841 caagagcaat aagggcatac caaaaatctg gttttagaat tattgaagat ttgccagaac
      901 atgaattaca cgagggcaaa aaagaagatt gttatttaat ggaatataga tatgatgata
      961 atgccacaaa tgttaaggca atgaaatatt taattgagca ttactttgat aatttcaaag
     1021 tagatagtat tgaaataatc ggtagtggtt atgatagtgt ggcatattta gttaataatg
     1081 aatacatttt taaaacaaaa tttagtacta ataagaaaaa aggttatgca aaagaaaaag
     1141 caatatataa ttttttaaat acaaatttag aaactaatgt aaaaattcct aatattgaat
     1201 attcgtatat tagtgatgaa ttatctatac taggttataa agaaattaaa ggaacttttt
     1261 taacaccaga aatttattct actatgtcag aagaagaaca aaatttgtta aaacgagata
     1321 ttgccagttt tttaagacaa atgcacggtt tagattatac agatattagt gaatgtacta
     1381 ttgataataa acaaaatgta ttagaagagt atatattgtt gcgtgaaact atttataatg
     1441 atttaactga tatagaaaaa gattatatag aaagttttat ggaaagacta aatgcaacaa
     1501 cagtttttga gggtaaaaag tgtttatgcc ataatgattt tagttgtaat catctattgt
     1561 tagatggcaa taatagatta actggaataa ttgattttgg agattctgga attatagatg
     1621 aatattgtga ttttatatac ttacttgaag atagtgaaga agaaatagga acaaattttg
     1681 gagaagatat attaagaatg tatggaaata tagatattga gaaagcaaaa gaatatcaag
     1741 atatagttga agaatattat cctattgaaa ctattgttta tggaattaaa aatattaaac
     1801 aggaatttat cgaaaatggt agaaaagaaa tttataaaag gacttataaa gattgattat
     1861 ataatatatg aaaagctatt ataaaagaca ttagtattaa atagtttaaa aaaatgaaaa
     1921 ataataaagg aagtgagtca agtccagact cctgtgtaaa atgctataca atgtttttac
     1981 catttctact tatcaaaatt gatgtatttt cttgaagaat aaatccattc atcatgtagg
     2041 tccataagaa cggctccaat taagcgattg gctgatgttt gattggggaa gatgcgaata
     2101 atcttttctc ttctgcgtac ttcttgattc agtcgttcaa ttagattggt actctttagt
     2161 cgattgtggg aatttccttg tacggtatat tgaaaggcgt cttcgaatcc atcatccaat
     2221 gatgcgcaag cttttgaata ttttggttga tcgatataat catgaatcaa tcgattttta
     2281 gcctcacgcg ctaagttaat atctgtgaac ttaaaaattc ctttaacagc ttctctgaaa
     2341 gattttgaat tttttttagg aatggtggta aagatatttc ttaggaagtg aacttggcat
     2401 ctttgccaac ttacgttggt gaaggatttt ctaatggcag agactaatcc tttgtgcgca
     2461 tcagaaataa cgagttccgt accttgtaaa ccgcgttctt ttaggtattc aaaaaatgtt
     2521 gtccaggtct cttcgctttc gccactttga atcatgaagc cgataatttc acggtcgcca
     2581 tctttggtta ttccaatcgc tatatgacag ctttttgaga gtactcgatt ttcttctcgt
     2641 acttttatat agagtacatc ggtcattaag taaggataat ttttttctga taataaacga
     2701 ttctgccact cgttaaccat aggttctagc tgttctgtta agctagaaac gaaggactta
     2761 gagacggatt taccacaaag ttcttccaca atttttgata ctttacgagt tgaaacgcct
     2821 gatacataca tttccaacat tgaagccatg agggcttttt cgtttcgttg ataacgttca
     2881 aacactgtgg gtgaaaaatg gccatcacgt gttctgggta cttttaattc tagcgtgcct
     2941 acacgtgtcg taaagctgcg ctcataatag ccatttcgtt gactttgtcg gttttctgtt
     3001 cgttcatatt cttttgcttg aatatattct gttcgttgat tttccattag ttgattaaat
     3061 accgttgtta aaatattttt agaaacgtca tcctttacag aatattcaat aatgctttga
     3121 atctcttcgc ttttcagtgt aaaatgtact tgggtcatgt aaaagtcctc ctgggtatgt
     3181 ttttgtcgtt aaaaacattg taccgtaaaa ggactgttat atggcctttt tacttttaca
     3241 caattatacg gactttatct atataaaggc gctgtcagag ttttttgact tagaacatac
     3301 attcattcaa gagactttaa acaagctagc agaacgccca aaaacggaca cacaactcga
     3361 tttgtttagc tatgatacag gctgaaaata aaacccgcac tatgccatta catttatatc
     3421 tatgatacgt gtttgttttt ctgtactgtt tcctgagtga ttagcagaaa tataaagatt
     3481 aaaattttaa ttgattatta ggaagagaag gagaatgtat cccgaaaact tttagttggc
     3541 ttggactgaa cgaagtgagg gaaaggctac taaaacgtcg aggggagtgg gagcgaagcg
     3601 cacacttgat cttttgaact tttttctaat acttgacttt ttttatgtat acagttacta
     3661 tgtatatagt aacactttat acaataggac tgtatattaa gaggagtgtc tttatatgat
     3721 tagaaatcca tatttacctt taactgaaac aactttttat attctgttag ttttaactgc
     3781 acctgctcat ggatatgcta ttattcaaga aattgataag ttaagtgagg gatcagttaa
     3841 ggtagctgct ggaactatgt acggagcgat tgaaaattta cttaaactta attggataga
     3901 agaaattcca agtagggaaa aaagaagaag agtttacaaa attactgatc tgggagaaga
     3961 agttttaaga ctagaaatag atcgtctagg aagtttgatt aagctatctt ctgattttgg
     4021 atattaggag gggataacat gaaaaaattt agaattttct attataaaaa aagattaaaa
     4081 atctgattat ctgcataaac acaagtactt taagtaatag gaatgaaaat acaaaagaaa
     4141 tttaccacta atttactacg attgaaagaa ccttgatacg ataaagaaaa atcgcataaa
     4201 aaagaaaaaa ggtatttcat acaagatatg agatgtcttt ttgttgctgt aacacagcat
     4261 aatttgttct tttttctgct tgattatcta tcatttttta gagcatgaat tgtcaagagc
     4321 ttgttgcgta agcaatgctt gcactcttga taaggcatgg gataaaaaat attctgacag
     4381 atagcagaaa agtaatgaac tgaaatgagg taagtgctat aatatattta tcaattttgg
     4441 aaaacgtgga gagatatatg gaaaagatat tagaaaacac attattactc atgatactgc
     4501 cttggatatt tgtctgggga atactatgta tcttagaaaa gagaaaacgg aaaaatgaag
     4561 acggaaataa agatgaaaaa agctatgtta tacaaaatga taatatgttc tttccctttt
     4621 tttcgttagg tatgttttta ttttcatttt gcctttttta tacggtgttt tttactgaat
     4681 ttgatatatc ggaagtaata tcagtttctg tctttgtcat attttttgct attttaacat
     4741 tagatagtgc aatctggaga gtaattgtag atggtgatat aatcaaatac cgttcatttt
     4801 atgggattac taggacatat aattttaatg atattaccaa aggagtttat actaagaaag
     4861 gttctttaaa aatatatatt gaggggaaaa gaatttttac attttatgat aatttagaat
     4921 tttctttatt tgaaaatcaa atgagaaaaa gaaaaattcc tttagaatat aaacgcaaag
     4981 aaaaataata aggaaattgt tcagaattag tttaataata ttaccacttt aaagacggag
     5041 tgatccagac acggtggcag ggaaatcttt cagatttttc tgccatgtct tgcaagtggc
     5101 tggttcactt cgtctgtgag cgagcctgtg gcgagcgaag attaagccct cgttatctaa
     5161 caggggggta ctattacaaa agacaagagc aaaaacaaat acaaaactgc tga
//
LOCUS       DAMJXI010000216         4960 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.guided.150, whole genome shotgun sequence.
ACCESSION   DAMJXI010000216 DAMJXI010000000
VERSION     DAMJXI010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4960
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.guided.150"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            <1..542
                     /locus_tag="PC465_004027"
     CDS             <1..542
                     /locus_tag="PC465_004027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2651228.1"
                     /translation="IGINMQSLSKIERGLNYPAYDTLEKIMEVLDVTPNELLSGEWKY
                     INQAEKEVCQFLRAEERLNTELKHGHYDNFFDSEEEWLEYELEKLREYITDYINGNNI
                     QAGDLYPIKEFIQHLKFQRLLDRYDDLYSMDMFGESIEGHKYKTPFQFVKRINPNSKE
                     DMELLREVLGNNHFDDEDE"
     gene            775..996
                     /locus_tag="PC465_004028"
     CDS             775..996
                     /locus_tag="PC465_004028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2651229.1"
                     /translation="MAKKNKYSFDSKIHVYRATKRMSQQELADLVGVSRQTIIQLERN
                     RYNPSMLLAYSIAKVFDVTIEDLFDFRED"
     gene            999..1340
                     /locus_tag="PC465_004029"
     CDS             999..1340
                     /locus_tag="PC465_004029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009269613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651230.1"
                     /translation="MLSLYEFLWNVFNSKTVLIIGAWASLSLTLILIVMFVRKQNRDE
                     RGWKIKGKASAIAFIYFIIMANLLAKAVGAMVPDTLEVGYVFCANVIQWLYDTMIFIE
                     IIAILILNKIE"
     gene            1678..2727
                     /gene="cfr(B)"
                     /locus_tag="PC465_004030"
     CDS             1678..2727
                     /gene="cfr(B)"
                     /locus_tag="PC465_004030"
                     /EC_number="2.1.1.224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(8))-methyltransferase
                     Cfr(B)"
                     /protein_id="HDF2651231.1"
                     /translation="MQQKNKYIRIQEFLKQNKFPNYRMKQITNAIFPGRINNFNEITV
                     LPKSLRDMLIEEFGESILNIVPLKAQQSTQVSKVLFGISGDEKIETVNMKYKAGWESF
                     CISSQCGCNFGCKFCATGDIGLKRNLTSDEITDQILYFHLQGHSIDSISFMGMGEALA
                     NVQVFDALNVLTDPALFALSPRRLSISTIGIIPNIKKLTQNYPQVNLTFSLHSPFNEQ
                     RSELMPINERYPLSDVMDTLDEHIRVTSRKVYIAYIMLHGVNDSIEHAKEVVNLLRGR
                     YRSGNLYHVNIIRYNPTVSSRMRFEEANEKCLVNFYKELKSAGIKVTIRSQFGIDIDA
                     ACGQLYGNYQKTNSQ"
     gene            3541..4008
                     /locus_tag="PC465_004031"
     CDS             3541..4008
                     /locus_tag="PC465_004031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2651232.1"
                     /translation="MATEKKVYKVINEAGLKALENKCIIVKYAPHNLSAKILEFFNSE
                     FYVLQLCEHEIVLIPFNLMTLNMTLKKEELLVIPYSRIKSIEISEDLLNYIISITTDT
                     DIIRLSTQQKELSNLRTSGSLTSKKAGITLENWHKDNLDITLEALKKIDTNSN"
     gene            4191..4610
                     /locus_tag="PC465_004032"
     CDS             4191..4610
                     /locus_tag="PC465_004032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009269612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase subunit sigma-70"
                     /protein_id="HDF2651233.1"
                     /translation="MNTSSFKDIVRLQFNSLMMIIIKGRVKYHKKQIMKRSKNEVLFC
                     EMSETERLEQGTVDTYIYDYVSFQVFHFTICVTDEKLATALNMLSKKQRSTILLRYFQ
                     GMNDREISELYHVSRSAIFSRRSRGLKKLKMLLSERK"
     gene            4616..4855
                     /locus_tag="PC465_004033"
     CDS             4616..4855
                     /locus_tag="PC465_004033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2651234.1"
                     /translation="MSKDYGYPSFELICRASSGDEVAIREILKFYDAYISKLCLRPFY
                     HCESGKIIMQVDEELKGEVYTDMMKAILKFEIRVK"
BASE COUNT         1806 a          649 c          967 g         1538 t
ORIGIN      
        1 aaatcggtat caatatgcag agcctttcca agattgaacg aggattgaat tatcctgcct
       61 atgatacgct ggaaaagata atggaagtgc tggacgtaac gcccaatgaa ctgttgtcgg
      121 gggaatggaa atatatcaat caggctgaaa aggaagtctg tcagtttcta agagccgaag
      181 aacgcctaaa tacagaactg aaacacgggc attatgacaa cttttttgat agtgaggaag
      241 aatggctgga atatgagtta gaaaagttac gggaatatat taccgactac atcaacggaa
      301 ataacataca ggcaggcgac ctttacccaa ttaaagaatt tatccagcat ttgaagtttc
      361 aaagattgtt agaccgatat gatgatttat acagcatgga tatgtttggg gaaagcatag
      421 agggacataa gtataaaaca ccttttcaat tcgtgaaacg gataaacccc aactcaaaag
      481 aagatatgga actgttacgg gaagtattag ggaataacca ttttgatgat gaggacgagt
      541 aatctttttc ctcttgtgag aagatacagc aaacaaaaag cccgatcaag agtgcaaagc
      601 accaccaatg gtggcaaagc tcttgacagg gctttttctg ttctgtgttg ggtaatcaag
      661 agggaaaaag ggatagttgc acgattttct cataaggtat taaaaacagc cacacaaaat
      721 gtaagaaata tgttataatc ggaaatggaa aattacgata aaggcggtgt atgagtggca
      781 aagaaaaata aatattcgtt tgatagcaaa attcatgttt accgagcgac aaaacgaatg
      841 agccagcagg aactcgctga ccttgtaggc gtatcacgac aaacgattat acagcttgag
      901 agaaatcgtt ataatccctc tatgttgttg gcatacagta ttgcgaaagt gtttgatgta
      961 acgattgaag atttatttga ttttagggag gattgactgt gttatcatta tacgaatttt
     1021 tatggaatgt atttaacagt aaaactgttt tgataattgg tgcatgggca agtttgtcac
     1081 ttacattgat attgattgta atgtttgtac gaaaacaaaa tcgagatgaa cgtgggtgga
     1141 aaattaaagg aaaagctagt gcgattgcct ttatctattt tataattatg gcaaatttac
     1201 ttgcaaaagc agttggagca atggtgcctg atactttgga agtaggttat gttttttgtg
     1261 ccaatgtaat ccaatggctt tatgatacga tgatatttat tgagattatt gcaattttaa
     1321 ttttaaataa aattgaataa ataaaagatt tcttgttttt catctaaatg ttaacggtaa
     1381 acggtgcagg ttagtttaac tacatttata tccaaaattg tttgtttttc aaattacatg
     1441 tatttttttg agtttacata gggaaagatt tatggtatac tatttaacac ttatattgac
     1501 aagaaagagg tgaaagcaat gttaactgtt tttagaattt tgtttggtaa aaatgcaaaa
     1561 gttggtaatc tttctctacg tattaatatc atgcagagag aaaatgttca actttttgtg
     1621 tccaaagtat tgacataggt ccaaacaaac cagagttata tggaaggatg agaaaacatg
     1681 caacaaaaaa ataagtatat aagaattcaa gagttcttga agcagaataa atttcctaat
     1741 tatagaatga aacaaattac aaatgctata ttcccaggga gaataaataa tttcaacgaa
     1801 ataacggttc ttcctaaatc actaagagat atgttaattg aggagtttgg agaatcgatt
     1861 ttaaatattg ttcctttaaa agcacaacaa tctacacaag tttcaaaagt cttatttgga
     1921 atttcaggag acgaaaaaat agaaacggta aatatgaaat ataaagctgg ttgggagtca
     1981 ttttgtatat catcgcagtg cggttgtaat tttggttgta aattttgtgc aactggagat
     2041 ataggtttaa aacgtaactt aacttcagat gaaattactg accagatttt gtactttcac
     2101 ttacaagggc attcaattga cagtatttct tttatgggaa tgggagaagc attagcgaat
     2161 gtacaagttt ttgatgcttt aaatgtactt acagatcctg cgttgtttgc tttaagtccg
     2221 cgtaggttat ctatatccac tataggaatt attccaaaca ttaaaaaatt gactcaaaac
     2281 tatccgcagg tcaacctgac attttcatta cattctcctt ttaatgaaca gcgaagtgag
     2341 ttaatgccaa ttaatgaacg ctacccatta tcagatgtga tggatacatt agatgagcat
     2401 atacgagtaa cctcaagaaa agtttatatt gcttatatta tgttgcacgg agttaatgat
     2461 tctattgaac atgcgaaaga agtcgtaaac cttttaagag gtagatatag gagtgggaac
     2521 ttgtatcatg tgaacatcat tagatataac ccgactgtta gttcacggat gcggtttgaa
     2581 gaagcaaatg agaaatgtct tgtcaacttt tataaagaat taaagtcagc aggaattaaa
     2641 gttaccatta gaagtcaatt tggcattgat atagacgctg cttgcggtca attgtatgga
     2701 aactatcaaa aaaccaatag ccagtaactt gaggtgagag tgatgtttag aacgtgggaa
     2761 gtaccctaat aatttattta gtaacgataa ataaacttat taggatattt atgataaaag
     2821 gaatcttaga aagaaaaata ggcatcactc aagtggagct aaaaagtcgt ttgtaaaaat
     2881 tgaaactgca attaaattat tgaatgtgaa aaatggtgat gattagtgtt aaacaaaaaa
     2941 ataatttcag tcaaagtatc agtagagatc atgtagtcat tacggatttt tggacgttga
     3001 ctgacaataa tgaaattcaa ctaccgtcca acatggaaat tatatgcaat aattatttga
     3061 agagtttgaa attgatgtat cagaagatta ctctaaacag tagttggaaa aatttgtcat
     3121 gcgagaattg cggatgcagt gaattattga taatcaggtg gaagacagta gtgtatccaa
     3181 tgaagagatg aacacgaata ccaaaaatca cttaaaataa ggtggatatg caaaaggaat
     3241 acaatcgtgt tatccttgat atgaaaagca agaaaagaaa tgggaaacat ttgttctcaa
     3301 tttaaaaagg caacgtcaat tgaaatattt ataatttcgc ttatctaaaa ggccttagag
     3361 catattttaa tgaacaaaat tgaaaggact gaacctataa taatgattca ctaatccata
     3421 aactatttta aataaatgag agcaagaatt tttttgcttc taaatgtaag aaatacttta
     3481 cttttagaat gaaatagtat aaaataaggg cgaatataaa aactcaagga ggaatgtatt
     3541 atggcaacag aaaaaaaggt ctataaggtt ataaatgagg ctggattgaa agcacttgaa
     3601 aacaaatgta ttattgtaaa atacgctccg cataatttga gtgcaaagat tctcgaattt
     3661 ttcaattcgg aattttatgt actacaactt tgtgagcatg aaattgtgtt aataccattc
     3721 aatcttatga cattgaatat gacgttaaaa aaagaagaac ttttagtaat tccatattct
     3781 cgaattaaaa gtattgagat ttcagaagat ttattgaatt atatcatttc aattacaaca
     3841 gatacagata ttattcgact atcaacacag caaaaagagc taagcaattt acgaacttct
     3901 ggcagtttga catcaaaaaa agctggaatc actttagaaa attggcataa agacaattta
     3961 gatataactt tagaagcgtt aaagaagata gatactaata gtaattaaaa catcttactt
     4021 ttatttttca atataaaggc tcgtgcaaaa caatatgttt tgtgcgggct ttttttcata
     4081 gacactttct tttctgatac gaaaccaaag gtatagacgg tatttctatt ttccgtattg
     4141 aaatattccg tttgtatatt tcagtttttg cagaaagggg gggtgaactt atgaatacat
     4201 cttctttcaa ggatattgtc agattgcagt ttaattcttt gatgatgatt atcattaagg
     4261 gcagggtaaa atatcataaa aagcagatta tgaaacgctc taaaaatgaa gttctgtttt
     4321 gcgaaatgtc agaaacagaa cggcttgaac agggaacagt tgatacatac atttatgatt
     4381 atgtatcgtt tcaagttttt cattttacga tttgtgtaac agatgaaaaa ctcgctacag
     4441 ctttaaatat gctatcgaaa aaacagcgta gtacgatttt attacgttat tttcaaggca
     4501 tgaatgacag agaaatttca gaattgtacc atgtatcacg ttctgctatt tttagcagaa
     4561 gaagtagagg actaaagaag ttaaaaatgc ttttaagcga aaggaagtaa aaagaatgag
     4621 caaagattat ggctatccct cttttgaatt gatttgcaga gcgtcaagcg gagatgaggt
     4681 ggcaatcaga gaaattttga agttttatga cgcttatatt tctaaattat gcttgcgacc
     4741 gttttaccac tgtgaaagtg gtaaaatcat tatgcaggtt gatgaagaac taaaaggaga
     4801 agtttataca gatatgatga aagcaatctt gaaatttgaa atacgagtga agtaatcaac
     4861 tgtataaaag aaaattggga gatacacagt tatttgtgct atctcccata gtggttttac
     4921 tgtcatatca aggctcattc aatcgtggta aattcgtggt
//
LOCUS       DAMJXI010000217         3384 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain L,15.7104308 isolate JH451
            SAMN32366264-rid16588653.guided.161, whole genome shotgun sequence.
ACCESSION   DAMJXI010000217 DAMJXI010000000
VERSION     DAMJXI010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366264
            Sequence Read Archive: SRR22862979
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560835.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560835.1
            Genome Coverage       :: 222x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:33:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,036
            CDSs (total)                      :: 3,954
            Genes (coding)                    :: 3,895
            CDSs (with protein)               :: 3,895
            Genes (RNA)                       :: 82
            rRNAs                             :: 4, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 25 of 59
            Pseudo Genes (incomplete)         :: 28 of 59
            Pseudo Genes (internal stop)      :: 19 of 59
            Pseudo Genes (multiple problems)  :: 9 of 59
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3384
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366264-rid16588653.guided.161"
                     /strain="L,15.7104308"
                     /isolate="JH451"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Bulgaria"
                     /collection_date="2015"
     gene            complement(60..477)
                     /locus_tag="PC465_004034"
                     /pseudo
     CDS             complement(60..477)
                     /locus_tag="PC465_004034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003505402.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            692..1213
                     /locus_tag="PC465_004035"
     CDS             692..1213
                     /locus_tag="PC465_004035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003505403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2651235.1"
                     /translation="MNPKIYLITGLMASGKSTVSDLLAKSIEKCVHLRGDVFRKMIIS
                     GRENMSATPSAEAVRQLYLRYKLTADAAKSYFDNGFSVVIQDNYYGDELNRMINYLHK
                     YPVEVIVLCPDVETIKERERYREKTGYSGFTVETLYDTFMQTTPRIGFWLDNSNQTPQ
                     QTAETILNARKSV"
     gene            1406..3325
                     /gene="tet(32)"
                     /locus_tag="PC465_004036"
     CDS             1406..3325
                     /gene="tet(32)"
                     /locus_tag="PC465_004036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003505402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(32)"
                     /protein_id="HDF2651236.1"
                     /translation="MKIINIGILAHVDAGKTTLTESLLYTSGAIAEQGNVDKGTTRTD
                     TMILERQRGITIQTAVTSFCWNDYKINIVDTPGHMDFLTEAYRSLSVLDGAVLVISAK
                     DGVQAQTRILFHALQKMDIPTIIFINKIDQNGIDLRRVYQSIKDKLTSDMIVMQEVSL
                     SPKITMTDISDLDKWDMIISGSDELLERYVAEDSLDIQELQYEKCKRTRCCSLFPVYH
                     GSAKDNLGTEKLIEAITETFITETDDIQSELCGYVFKVEYTERKKRLSYLRLYHGTLH
                     LRDTLLLSKKEKIKITEMCIPSNGEIVPVDHACPGEIVILADDTLKLNDILGNEKLLP
                     HKTRIDNPMPLLRTTVEPQKPEQREALLNALAEIADTDPLLHFDIDTVTHEIILSFLG
                     KVQLEVICSLLEEKYHVGVAMKEPSVIYLERPQKKASCTIHIEVPPNPFWASIGLTVT
                     PLPVGSGTQYKSEVSLGYLNQSFQNAVMEGVRYGMEQGLYGWGVTDCQICFDYGVYYS
                     PVSTPADFRFLAPVVLEQALKKAGTQLLEPYLSFTLFAPQEYLSRAYNDAPKYCAIIE
                     STRLEKDEVIFKGEIPARCIGEYRNDLNFYTNGRSVCITELKGYQETSGEPVFQPRRP
                     NSRLDKIRHMFQKIM"
BASE COUNT         1073 a          654 c          700 g          957 t
ORIGIN      
        1 tgattttatc aatgatattt cgcaatagcc agcaatgaac acttgcattg cgcaagacat
       61 tacattatct tctgaaacat atggcgaacc ttatctaacc gactatttgg gcggcaaggt
      121 tgtactacag gttcctctga agtttcctga taccctttca attctgccaa gcaaacgctt
      181 cttccatttg tatagaaatt caaatcactt ttatattccc cgatccgccg agctggtatt
      241 tctccagtta aaattgcctc attattttat aacgaagttg tttcaattac cgcatcatat
      301 ttcacagcat catgataagt tcgtgaaaga tattcctgtg gcgcaaatag ggtaaaagaa
      361 agatagggtt ctaaaacttg tgttcccgct tttttatacc tgttccaaca caacaggcgc
      421 aagaaggcgg aaatctgccg gagtactgac cgggccgtaa taaacaccat attcaaagct
      481 gaaccaaaga ccaaaaaata agcattgtgg gaaaatttaa acttttggat tttcctacaa
      541 tgccgactac ggcggaatcc ctcccactcc ttataccttt ctttccgtat acattgaatt
      601 tgtatttagt aactgctata atgtccctat tcaaattaaa aatgtgttga attagttaca
      661 tgtacatatt ttttgtaccg gaggaagtga aatgaatcca aaaatttatc tcattacagg
      721 cttaatggct tctggaaaat ctacagtttc cgatttactg gcaaaatcaa tagaaaaatg
      781 cgtccatctt cgtggtgatg tgttccgaaa aatgattatt tcaggcagag aaaatatgtc
      841 agctacccca tcagcggaag cagtccgcca gctgtacctt cgatacaaat tgactgctga
      901 tgcggcaaag tcatactttg ataacggctt ttctgtagtg atccaagata actactacgg
      961 tgatgaatta aaccgaatga taaattatct gcataaatac cctgttgagg ttatcgttct
     1021 ttgtccagat gtggaaacaa taaaagaaag ggaacgatac agggagaaaa caggctattc
     1081 cggctttacg gtcgaaacct tatacgatac atttatgcag acaacaccac ggatcggctt
     1141 ttggctggac aattccaacc aaacaccaca gcagacagca gaaaccattc tgaacgccag
     1201 aaagtcggta tgattgttac atataagggg aagaaaaatt tcttttaggt actttctttc
     1261 ctaaaactaa tgtgatataa tagcatcatt ccaaaaaagg agtaaaaaat atgcggcaag
     1321 gtattcttaa ataaaactat agtaaaagta ttttactgct ggggattttt atgccctttt
     1381 ggggctgtaa aaggaggaca atcacatgaa aataatcaat attggaattc tcgcccatgt
     1441 agacgcagga aaaacaacat tgacggaaag cctgctgtac accagtggag cgattgcgga
     1501 acaaggaaac gtggataaag gaactacaag aacagacact atgattttgg aacggcaacg
     1561 gggaattact attcagacag cggttacttc tttttgctgg aatgattata aaatcaatat
     1621 tgtggacact cccggccata tggatttttt aaccgaagca taccgctctt tatctgtcct
     1681 tgacggagct gttttagtca tttcggcaaa agacggcgta caggcacaaa cccgtatatt
     1741 attccatgcg cttcagaaaa tggacatccc gacaattatc tttataaata agatagacca
     1801 aaatgggatc gacctgcggc gtgtttacca aagcattaaa gataaactta ccagtgatat
     1861 gattgtcatg caggaggttt ccctgtcgcc aaagataacc atgaccgata tttctgattt
     1921 ggacaaatgg gatatgatta tttccggaag cgatgaacta ttagaacgat atgttgcaga
     1981 ggattctttg gatatacagg aattacaata tgaaaagtgc aaaagaacca gatgctgctc
     2041 tttgtttcct gtttatcatg ggagtgcaaa agacaattta ggaacagaaa aactgattga
     2101 agcgattaca gaaactttca ttacagaaac agacgatatt cagtctgaat tatgtggata
     2161 tgtttttaag gttgagtata cagagcggaa aaaacggctt tcttatttac gcctgtatca
     2221 tgggacgctc catttacggg ataccctgct gctgtcaaaa aaggaaaaaa taaagattac
     2281 agaaatgtgt attccgtcaa atggtgaaat cgtcccggtt gaccatgcct gtccgggaga
     2341 aattgttatt ttagctgatg atactttgaa actgaacgac attctgggaa atgaaaaact
     2401 cctgcctcac aaaacacgga ttgataatcc catgccatta cttcggacaa cggtagagcc
     2461 gcaaaagccg gagcaaaggg aagccctgtt aaatgccctc gcagagattg ctgatacaga
     2521 ccctcttttg cattttgaca ttgatactgt tacacatgag attatattat cttttttggg
     2581 aaaagtacag ttagaagtta tttgttcgct attagaagaa aaatatcatg tgggcgtggc
     2641 tatgaaagag ccttcggtta tttatctgga aagaccgcaa aaaaaagcga gctgcacgat
     2701 tcatattgaa gtgccgccga atccgttttg ggcatctatt ggtctgactg taacaccgct
     2761 tcctgttgga agcggaacac aatataaaag cgaggtatct ctcggctatt taaaccaaag
     2821 ttttcaaaat gccgtcatgg agggtgtgcg ttatggaatg gagcagggct tatatggctg
     2881 gggagtgaca gactgccaaa tttgttttga ttatggagtt tattacagcc cggtcagcac
     2941 ccccgctgat tttcgttttc ttgcgcctgt cgtgttggag caggcattga aaaaagcagg
     3001 aacacaactg ttggaaccat acctttcctt tacccttttt gcaccgcagg aatatctttc
     3061 acgggcttat aatgacgcac caaagtattg cgcaatcatt gaatcaacca gacttgaaaa
     3121 agatgaagtt atttttaagg gggaaatccc tgcccgttgt atcggtgaat atagaaatga
     3181 tttgaatttt tatacaaatg gaagaagtgt ctgcattaca gaattaaaag ggtatcagga
     3241 aacttccggc gagcctgtgt ttcagccacg ccgcccgaac agccgtttag acaagatccg
     3301 gcatatgttt cagaagataa tgtaacatct tgcgcaatgc aaacgttcat tgctggctat
     3361 tgcgaaatat cattgataaa atca
//
